Legend,,,,,,,,,,,,,,,,,,,,,,,
Supplemental File 3 contains all the the FisherΥs exact test conducted with the MedDRA and DrugBank mappings. ,,,,,,,,,,,,,,,,,,,,,,,
_ΚΚΚΚΚ Drug - Drug Bank ID,,drug,adverse_event,a,b,c,d,p-value,ROR,conf_1,conf_2,BH,comb,neg_log_p,logROR,color,pt_id,pt_term,soc_id,soc_term,soc_short,drug_name,drug_id
_ΚΚΚΚΚ Adverse_event - MedDRA preferred term id,1,DB00005,10004146,87,127995,27,42392,0.828968482,1.067195743,0.685967484,1.710363543,0.910150159,DB0000510004146_,0.094145683,0.065034407,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,etanercept,DB00005
_ΚΚΚΚΚ a - the number of female patients with target drug-adverse event pairs,2,DB00005,10005724,86,127996,12,42407,0.003194473,2.374539545,1.291599813,4.773815609,0.01424321,DB0000510005724_,4.251474998,0.864803543,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,etanercept,DB00005
"_ΚΚΚΚΚ b - the number of female patients with the drug but not the same adverse event,",3,DB00005,10006784,467,127615,116,42303,0.005322084,1.334511693,1.086439005,1.650427053,0.02150019,DB0000510006784_,3.839693492,0.288565452,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,etanercept,DB00005
"_ΚΚΚΚΚ c - the number of male patients with target drug-adverse event pairs,",4,DB00005,10013538,305,127777,85,42334,0.177260047,1.188818724,0.931668159,1.530716083,0.320346546,DB0000510013538_,1.138351913,0.172960145,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,etanercept,DB00005
_ΚΚΚΚΚ d - the number of male patients with the drug but not the same adverse event.,5,DB00005,10016256,4710,123372,1133,41286,4.60857196795254e-24,1.3911244,1.30224297,1.487093764,6.63760625630863e-22,DB0000510016256_,48.76412065,0.330112341,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
_ΚΚΚΚΚ p-value - raw p-values from Fisher's exact test,6,DB00005,10016322,1982,126100,557,41862,0.000519388,1.181276034,1.074007286,1.300854389,0.003185651,DB0000510016322_,5.749098517,0.166595239,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
_ΚΚΚΚΚ ROR- the reporting odds ratio,7,DB00005,10017577,1787,126295,510,41909,0.002793205,1.162716893,1.052494746,1.286254379,0.012750401,DB0000510017577_,4.362192559,0.150759416,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
_ΚΚΚΚΚ conf_1 - lower boundary of the confidence interval 95%,9,DB00005,10039073,4938,123144,1215,41204,2.97999953444155e-22,1.359850399,1.275550429,1.450531454,3.86811297594055e-20,DB0000510039073_,44.69893507,0.307374693,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
_ΚΚΚΚΚ conf_2- upper boundary of the confidence interval 95%,10,DB00005,10044034,282,127800,89,42330,0.718690064,1.049454037,0.823962402,1.347731201,0.833900649,DB0000510044034_,0.18164101,0.048270064,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
_ΚΚΚΚΚ BH - BH adjusted p-value from the raw p-values from Fisher's exact test,11,DB00005,10046571,1612,126470,126,42293,1.31137354295801e-82,4.278426103,3.56577743,5.171712474,1.86321370684602e-79,DB0000510046571_,181.2819196,1.453585209,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,etanercept,DB00005
_ΚΚΚΚΚ comb- Drug Bank ID and MedDRA id ,13,DB00412,10003658,96,968,156,1230,0.080938477,0.782023854,0.591578396,1.029791315,0.179958371,DB0041210003658_,1.715029724,-0.245870036,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
_ΚΚΚΚΚ neg_log_p - negative log BH adjusted p-value,14,DB00412,10028596,418,646,641,745,0.000635668,0.752137394,0.637259366,0.887310951,0.003781922,DB0041210028596_,5.577522982,-0.284836267,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
_ΚΚΚΚΚ logROR - log reporting odds ratio,15,DB00005,10022061,12207,115875,1646,40773,0,2.609513859,2.475177253,2.752315401,0,DB0000510022061_,Inf,0.959163943,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
_ΚΚΚΚΚ color - color for plotting ,16,DB00005,10022075,956,127126,141,42278,5.9602729223439e-23,2.254987792,1.886933941,2.711383703,8.05479556626269e-21,DB0000510022075_,46.26801932,0.813144559,NA,10022075,Injection site induration,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
_ΚΚΚΚΚ pt_id - MedDRA preferred term id,17,DB00005,10022093,6995,121087,898,41521,3.22947699246371e-207,2.670875048,2.489196474,2.869020695,2.82956009156362e-203,DB0000510022093_,466.3846526,0.982406152,NA,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
_ΚΚΚΚΚ pt_term - MedDRA preferred term ,18,DB00005,10022095,5878,122204,853,41566,2.48404070961518e-141,2.343886422,2.179120454,2.523430662,1.18714563731336e-137,DB0000510022095_,315.2826059,0.851810416,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
_ΚΚΚΚΚ soc_id - MedDRA system organ class term id,19,DB00005,10022107,1951,126131,181,42238,2.43649052902789e-85,3.609722167,3.096893873,4.228807529,3.767244326794e-82,DB0000510022107_,187.4856338,1.283630807,female,10022107,Injection site urticaria,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
_ΚΚΚΚΚ soc_term - MedDRA system organ class term ,20,DB00005,10022112,2898,125184,311,42108,5.93699431460244e-108,3.134542283,2.785984272,3.536373815,1.20041458122558e-104,DB0000510022112_,239.2861827,1.142483161,female,10022112,Injection site warmth,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
_ΚΚΚΚΚ soc_short - MedDRA system organ class short term,21,DB00005,10033371,7553,120529,2325,40094,0.00142597,1.080647045,1.030026876,1.13409005,0.007372467,DB0000510033371_,4.91000293,0.077559977,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
_ΚΚΚΚΚ drug_name - drug name ,22,DB00005,10047899,892,127190,181,42238,2.52512983126826e-10,1.636511476,1.392854204,1.931617607,7.74481185704624e-09,DB0000510047899_,18.67624266,0.492566827,NA,10047899,Weight increased,10022891,Investigations,Inv,etanercept,DB00005
_ΚΚΚΚΚ drug_id - Drug Bank ID,23,DB00005,10051572,1229,126853,186,42233,8.18152345708811e-28,2.19995616,1.883267284,2.581711409,1.5697178399238e-25,DB0000510051572_,57.11373144,0.788437433,NA,10051572,Injection site discolouration,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,24,DB00254,10000081,118,5817,37,3351,0.000974875,1.837086216,1.256728125,2.741816297,0.005395216,DB0025410000081_,5.222242587,0.608180738,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,doxycycline,DB00254
,25,DB01240,10000081,248,5503,52,1524,0.073113993,1.320731759,0.970254306,1.827005198,0.166709354,DB0124010000081_,1.791503375,0.278185946,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,26,DB00254,10012735,311,5624,150,3238,0.082403539,1.193651952,0.974317926,1.467457372,0.182367351,DB0025410012735_,1.701732216,0.177017475,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,doxycycline,DB00254
,27,DB01240,10012735,1327,4424,283,1293,1.08917916102888e-05,1.370408712,1.186565362,1.586284885,0.000116758,DB0124010012735_,9.0554067,0.315109025,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,28,DB00254,10013700,1119,4816,181,3207,6.78348269378529e-83,4.11615472,3.491867295,4.873478095,1.01887910060655e-79,DB0025410013700_,181.8855192,1.414919407,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,doxycycline,DB00254
,29,DB01240,10013700,43,5708,12,1564,1,0.981839979,0.507118582,2.050538584,1,DB0124010013700_,0,-0.018326939,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,epoprostenol,DB01240
,32,DB00254,10028813,410,5525,134,3254,2.01719647086022e-09,1.801931407,1.471634035,2.217493178,5.26795918892807e-08,DB0025410028813_,16.75903771,0.588859094,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,doxycycline,DB00254
,33,DB01240,10028813,1225,4526,230,1346,1.56854767650114e-09,1.583848115,1.356368557,1.854984909,4.1899670403285e-08,DB0124010028813_,16.98798788,0.459857402,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,34,DB00254,10035664,210,5725,162,3226,0.003530547,0.730503211,0.5894736,0.906485312,0.015425602,DB0025410035664_,4.171726673,-0.314021652,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,doxycycline,DB00254
,35,DB01240,10035664,542,5209,120,1456,0.025675875,1.262429501,1.024837911,1.564804143,0.074990404,DB0124010035664_,2.590395117,0.23303804,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,36,DB00254,10047700,247,5688,73,3315,1.60803805648086e-07,1.971826933,1.507219807,2.606017937,2.79268452689788e-06,DB0025410047700_,12.78850723,0.67896049,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,doxycycline,DB00254
,37,DB01240,10047700,671,5080,116,1460,5.13488559746658e-07,1.662394504,1.350715459,2.059924465,7.93943928996524e-06,DB0124010047700_,11.7436679,0.508259035,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,38,DB00451,10005483,198,47073,113,15306,4.50292461116973e-06,0.569746117,0.449588493,0.724922883,5.39960645093962e-05,DB0045110005483_,9.826599394,-0.562564426,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,levothyroxine,DB00451
,39,DB00455,10005483,30,9371,22,5096,0.309541314,0.741593136,0.41319827,1.350730166,0.476992141,DB0045510005483_,0.740255265,-0.29895452,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,loratadine,DB00455
,40,DB00695,10005483,220,27829,249,20279,2.43027023080317e-06,0.643850683,0.534083944,0.775711581,3.14059257702366e-05,DB0069510005483_,10.36851396,-0.440288439,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,furosemide,DB00695
,41,DB01118,10005483,23,3040,52,4657,0.124342834,0.677607324,0.394909614,1.129691348,0.247602378,DB0111810005483_,1.395931135,-0.389187327,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,amiodarone,DB01118
,43,DB00451,10013573,1797,45474,450,14969,1.80429456220415e-07,1.314488924,1.182797536,1.463306984,3.09064076686453e-06,DB0045110013573_,12.68713212,0.27344794,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,44,DB00455,10013573,357,9044,154,4964,0.01418369,1.272384832,1.046893504,1.552193942,0.047077288,DB0045510013573_,3.055964596,0.24089296,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,45,DB00695,10013573,1188,26861,696,19832,1.71338333923191e-06,1.260228209,1.144562042,1.388337848,2.31370568053998e-05,DB0069510013573_,10.67407504,0.231292823,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,46,DB01118,10013573,83,2980,173,4536,0.022654026,0.730307887,0.552911257,0.95834534,0.068091604,DB0111810013573_,2.686901366,-0.31428907,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,amiodarone,DB01118
,47,DB08893,10013573,77,2008,45,1013,0.436126555,0.863273773,0.585062932,1.28661001,0.604715224,DB0889310013573_,0.502997635,-0.147023405,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,mirabegron,DB08893
,48,DB00451,10039101,305,46966,54,15365,1.16458675296331e-05,1.84769198,1.378870634,2.517561238,0.000124007,DB0045110039101_,8.995171404,0.613937282,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,49,DB00455,10039101,77,9324,31,5087,0.15849249,1.355126456,0.88106859,2.13095037,0.295490662,DB0045510039101_,1.219118045,0.303894775,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,50,DB00695,10039101,213,27836,71,20457,1.6696928847841e-09,2.20467995,1.676850341,2.928239872,4.43311893702526e-08,DB0069510039101_,16.93157736,0.790582351,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,53,DB00451,10074903,258,47013,54,15365,0.002371832,1.561439397,1.159921779,2.135984496,0.011181252,DB0045110074903_,4.493516845,0.445608086,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,54,DB00455,10074903,39,9362,16,5102,0.39712647,1.328344619,0.724569789,2.548895312,0.566753679,DB0045510074903_,0.567830498,0.28393352,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,55,DB00695,10074903,119,27930,34,20494,2.57394893154787e-07,2.568093566,1.740558788,3.880870359,4.25778777002742e-06,DB0069510074903_,12.36676084,0.943163821,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,57,DB08893,10074903,91,1994,37,1021,0.253755771,1.259282054,0.843474724,1.913323051,0.414271013,DB0889310074903_,0.881234898,0.23054176,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,mirabegron,DB08893
,60,DB01062,10013709,307,4179,101,1644,0.138198474,1.19571881,0.944675821,1.523495141,0.267236583,DB0106210013709_,1.319620932,0.178747519,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,63,DB01062,10041349,59,4427,18,1727,0.44348754,1.278612017,0.741123109,2.310450663,0.611598636,DB0106210041349_,0.491679036,0.245775128,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,68,DB00559,10000059,113,9546,42,3264,0.643444191,0.919934495,0.638668919,1.347276865,0.779818831,DB0055910000059_,0.248693655,-0.083452813,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,71,DB00559,10035664,733,8926,214,3092,0.033221771,1.186489326,1.011727694,1.395848941,0.091771711,DB0055910035664_,2.388451184,0.170998801,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,bosentan,DB00559
,73,DB00559,10047700,433,9226,98,3208,0.000107339,1.536342006,1.226284244,1.940211253,0.000847777,DB0055910047700_,7.072892447,0.42940427,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,74,DB06403,10037400,436,21035,160,6501,0.071428849,0.842157408,0.699479704,1.018105458,0.163738482,DB0640310037400_,1.809484746,-0.171788337,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,75,DB06403,10039710,88,21383,7,6654,4.97132223351719e-05,3.911949725,1.819786779,10.01912007,0.000439526,DB0640310039710_,7.729812727,1.364035901,female,10039710,Scleroderma,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,78,DB06403,10061818,147,21324,40,6621,0.491001563,1.141063206,0.798699717,1.663618161,0.654195868,DB0640310061818_,0.42434848,0.131960465,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,79,DB00005,10003239,7720,120362,2642,39777,0.13345882,0.965664803,0.922453412,1.011137392,0.260611797,DB0000510003239_,1.344723347,-0.0349385,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,80,DB00005,10022086,14440,113642,3136,39283,2.01847971463492e-122,1.59168016,1.528629451,1.657702108,5.30557392991788e-119,DB0000510022086_,272.3388681,0.464790163,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,81,DB00005,10033425,5525,122557,1589,40830,3.14591228514187e-07,1.158371322,1.09408975,1.226954232,5.10119089543208e-06,DB0000510033425_,12.18603654,0.147014986,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,82,DB00005,10053425,6691,121391,1065,41354,1.62089975785085e-134,2.140287317,2.003976719,2.287468134,6.08647859072993e-131,DB0000510053425_,299.8325775,0.76094008,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,86,DB00005,10007559,172,127910,53,42366,0.699837284,1.074892977,0.785628724,1.491902839,0.819622255,DB0000510007559_,0.19891171,0.072221101,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,etanercept,DB00005
,87,DB00005,10007882,438,127644,145,42274,1,1.000412354,0.827013148,1.215967323,1,DB0000510007882_,0,0.000412269,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,etanercept,DB00005
,88,DB00005,10022052,5216,122866,819,41600,2.57568195059486e-107,2.156366105,2.001174733,2.325875767,5.014948153436e-104,DB0000510022052_,237.8564266,0.768424446,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,89,DB00005,10051085,78,128004,25,42394,1,1.033337717,0.651158729,1.692954047,1,DB0000510051085_,0,0.032794066,NA,10051085,Endodontic procedure,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,91,DB00363,10010305,41,4587,52,6836,0.458313224,1.175020942,0.759411097,1.807416402,0.625675864,DB0036310010305_,0.468922831,0.16128597,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,92,DB00567,10010305,42,4477,26,2055,0.239010428,0.741496026,0.442778193,1.263514857,0.396751266,DB0056710010305_,0.924445728,-0.299085476,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,cephalexin,DB00567
,93,DB00363,10019063,34,4594,52,6836,1,0.972941779,0.611203552,1.530614013,1,DB0036310019063_,0,-0.027431035,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,95,DB00363,10021789,28,4600,35,6853,0.520437495,1.191800826,0.697348895,2.019630712,0.679534029,DB0036310021789_,0.386347966,0.175465462,NA,10021789,Infection,10021881,Infections and infestations,Infec,clozapine,DB00363
,96,DB00567,10021789,77,4442,30,2051,0.46441247,1.185060146,0.765173638,1.878546237,0.631509662,DB0056710021789_,0.459642038,0.169793529,NA,10021789,Infection,10021881,Infections and infestations,Infec,cephalexin,DB00567
,97,DB00363,10048294,41,4587,71,6817,0.498022988,0.858239994,0.568467139,1.280628151,0.660081963,DB0036310048294_,0.415391266,-0.152871506,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,103,DB00005,10012378,808,127274,212,42207,0.002260724,1.263910791,1.084770994,1.477923415,0.010751426,DB0000510012378_,4.532716842,0.234210716,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,104,DB00005,10013774,338,127744,48,42371,1.85212174078357e-09,2.335746827,1.722108788,3.230592523,4.86830199564962e-08,DB0000510013774_,16.83793553,0.84833168,NA,10013774,Dry eye,10015919,Eye disorders,Eye,etanercept,DB00005
,105,DB00005,10062244,427,127655,119,42300,0.101707187,1.18899913,0.967915855,1.469847614,0.213485599,DB0000510062244_,1.544185901,0.173111886,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,107,DB00363,10061920,100,4528,118,6770,0.093988461,1.267028288,0.958209505,1.672705361,0.20173002,DB0036310061920_,1.600825009,0.236674228,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,108,DB00203,10003549,603,13275,270,8668,2.78823320926047e-07,1.458245628,1.257813454,1.693959369,4.57625413084055e-06,DB0020310003549_,12.29462977,0.377234088,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,109,DB00374,10003549,730,16986,212,5512,0.175422504,1.117384041,0.954618205,1.312190265,0.317942121,DB0037410003549_,1.145885921,0.110990275,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,110,DB00203,10017918,53,13825,24,8914,0.16163098,1.423854232,0.862967123,2.413697737,0.299608717,DB0020310017918_,1.205277932,0.353367443,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,sildenafil,DB00203
,111,DB00374,10017918,66,17650,18,5706,0.61117175,1.185370662,0.694696836,2.12355227,0.753242376,DB0037410017918_,0.283368222,0.170055521,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,treprostinil,DB00374
,112,DB00203,10020772,136,13742,106,8832,0.145374807,0.824611644,0.634024815,1.074849375,0.277580764,DB0020310020772_,1.281643346,-0.192842738,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,sildenafil,DB00203
,113,DB00374,10020772,115,17601,34,5690,0.702581662,1.093432542,0.739116431,1.655946383,0.821576595,DB0037410020772_,0.196530108,0.089321869,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,treprostinil,DB00374
,116,DB00203,10002034,372,13506,152,8786,9.47941687933724e-07,1.59204344,1.312176529,1.939326117,1.36641882464151e-05,DB0020310002034_,11.20073214,0.465018373,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,sildenafil,DB00203
,117,DB00559,10002034,231,9428,45,3261,0.000268741,1.775543083,1.281882394,2.507613538,0.001844106,DB0055910002034_,6.29576058,0.574106339,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,bosentan,DB00559
,118,DB00203,10003239,450,13428,193,8745,1.01877367737601e-06,1.518433348,1.277104552,1.810783046,1.45377123288971e-05,DB0020310003239_,11.13876443,0.417679111,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,119,DB00559,10003239,157,9502,31,3275,0.004005986,1.745574444,1.178797084,2.66123052,0.017100666,DB0055910003239_,4.068637864,0.557083696,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,bosentan,DB00559
,120,DB00203,10003658,260,13618,136,8802,0.048468449,1.235640233,0.998537872,1.53470262,0.122204322,DB0020310003658_,2.102060866,0.211589243,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,sildenafil,DB00203
,121,DB00559,10003658,248,9411,79,3227,0.607508001,1.076428412,0.829610951,1.409373696,0.750427549,DB0055910003658_,0.287112169,0.073648535,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,bosentan,DB00559
,122,DB00203,10017955,145,13733,107,8831,0.299248816,0.871430904,0.673123142,1.13108928,0.465251889,DB0020310017955_,0.765176323,-0.137618701,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,123,DB00559,10017955,125,9534,32,3274,0.166519301,1.341366644,0.901508807,2.049083045,0.30615604,DB0055910017955_,1.183660373,0.293688978,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,125,DB06228,10042361,89,15823,194,15882,5.06298399432632e-10,0.460486469,0.353823213,0.595405539,1.48444544663544e-08,DB0622810042361_,18.02563948,-0.775471807,NA,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,128,DB01164,10008190,114,6410,90,7846,0.002240738,1.550363472,1.163237681,2.071572055,0.010668925,DB0116410008190_,4.540419981,0.438489401,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,calcium chloride,DB01164
,130,DB01164,10020919,448,6076,558,7378,0.717927842,0.974908808,0.85499166,1.111199148,0.833478562,DB0116410020919_,0.182147298,-0.025411342,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,calcium chloride,DB01164
,131,DB01164,10016807,81,6443,133,7803,0.031990887,0.737592561,0.551387872,0.981615783,0.089090478,DB0116410016807_,2.418102819,-0.304363693,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,calcium chloride,DB01164
,142,DB00316,10008111,83,65391,72,36881,0.009233916,0.650147751,0.468343352,0.904502851,0.033397109,DB0031610008111_,3.399285951,-0.430555632,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,144,DB00381,10008111,55,29305,36,22851,0.459731488,1.191302507,0.768294265,1.867792207,0.627176482,DB0038110008111_,0.466527308,0.175047252,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,146,DB00999,10008111,23,21407,36,12203,0.000188925,0.364207388,0.205969588,0.63198884,0.0013735,DB0099910008111_,6.590393216,-1.010031827,male,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,147,DB06228,10008111,220,15692,298,15778,0.000880263,0.742310614,0.619872439,0.88785688,0.004960914,DB0622810008111_,5.306165303,-0.297987506,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,148,DB00316,10008190,472,65002,297,36656,0.141720895,0.896201637,0.773002524,1.040339221,0.272155889,DB0031610008190_,1.301380255,-0.10958985,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,149,DB00335,10008190,92,8374,64,5401,0.680289523,0.927153807,0.665317946,1.2987807,0.80660187,DB0033510008190_,0.214925079,-0.075635808,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,150,DB00381,10008190,327,29033,284,22603,0.189385302,0.896406448,0.761555518,1.05563786,0.335761006,DB0038110008190_,1.091355664,-0.109361344,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,151,DB00588,10008190,145,16379,92,8376,0.112778682,0.806013814,0.615566153,1.059809108,0.230246199,DB0058810008190_,1.468606112,-0.215654398,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,152,DB00999,10008190,198,21232,147,12092,0.018004047,0.767129476,0.615809404,0.957315253,0.056858312,DB0099910008190_,2.867192862,-0.265099683,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,153,DB06228,10008190,474,15438,431,15645,0.112960292,1.114509904,0.97425278,1.275255805,0.230524943,DB0622810008190_,1.467396208,0.10841476,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,154,DB00316,10008479,926,64548,493,36460,0.303094637,1.060961902,0.94936628,1.186798603,0.469535437,DB0031610008479_,0.756011505,0.059175951,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,155,DB00335,10008479,111,8355,73,5392,0.939447252,0.98129832,0.722296063,1.339953901,0.978949994,DB0033510008479_,0.021274716,-0.018878767,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,156,DB00381,10008479,506,28854,308,22579,0.000547132,1.285570848,1.112359959,1.487678247,0.003324403,DB0038110008479_,5.706465107,0.251202859,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,157,DB00588,10008479,318,16206,122,8346,0.006011495,1.342358084,1.084211674,1.670697732,0.023702415,DB0058810008479_,3.742178329,0.294427832,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,158,DB00999,10008479,264,21166,141,12098,0.533265448,1.070191501,0.867898042,1.324161918,0.690027927,DB0099910008479_,0.371023208,0.067837605,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,159,DB06228,10008479,222,15690,153,15923,0.000266423,1.472501938,1.191612461,1.823531651,0.001831791,DB0622810008479_,6.302461306,0.386962953,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,160,DB00316,10040752,80,65394,55,36898,0.281857635,0.820727066,0.57485959,1.179163589,0.445819469,DB0031610040752_,0.807841187,-0.197564665,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,162,DB00381,10040752,20,29340,41,22846,0.000257109,0.37984179,0.210765107,0.663586205,0.001777982,DB0038110040752_,6.332276326,-0.968000456,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,amlodipine,DB00381
,166,DB00559,10011906,1238,8421,517,2789,5.41150228879731e-05,0.793070819,0.708815774,0.888213519,0.00047217,DB0055910011906_,7.658170588,-0.231842756,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,171,DB00374,10037400,642,17074,217,5507,0.571091587,0.954233066,0.814299007,1.121554585,0.721453007,DB0037410037400_,0.326488035,-0.046847333,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,172,DB00559,10037400,273,9386,113,3193,0.085752598,0.821857988,0.655142535,1.036510813,0.187943554,DB0055910037400_,1.671613605,-0.196187663,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,173,DB00820,10037400,424,11491,127,5689,4.56215753248826e-07,1.652832718,1.348866349,2.036791156,7.1442544379776e-06,DB0082010037400_,11.8492021,0.502490615,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,174,DB08932,10037400,740,18703,273,6324,0.238325599,0.916531221,0.794272399,1.060010467,0.395966523,DB0893210037400_,0.92642561,-0.087159147,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,175,DB00374,10061818,308,17408,94,5630,0.681882564,1.059680419,0.836802346,1.352386109,0.807573361,DB0037410061818_,0.213721378,0.057967371,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,176,DB00559,10061818,154,9505,62,3244,0.271298227,0.847767792,0.625524574,1.160836734,0.434054044,DB0055910061818_,0.834586228,-0.16514851,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,177,DB00820,10061818,186,11729,93,5723,0.847288155,0.975854296,0.755199614,1.268220444,0.923436059,DB0082010061818_,0.079653719,-0.02444199,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,178,DB08932,10061818,387,19056,144,6453,0.338424502,0.910071324,0.748071689,1.112131755,0.507487124,DB0893210061818_,0.678283941,-0.094232305,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,179,DB00203,10007554,262,13616,138,8800,0.055860128,1.226998643,0.992831741,1.521811982,0.13583269,DB0020310007554_,1.99633137,0.20457106,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,sildenafil,DB00203
,180,DB00559,10007554,164,9495,75,3231,0.042784212,0.744106713,0.561094939,0.994423047,0.111278746,DB0055910007554_,2.195716997,-0.295570823,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,bosentan,DB00559
,181,DB00682,10007554,222,19237,144,16220,0.015198685,1.299870988,1.048084744,1.616290003,0.049834397,DB0068210007554_,2.999049832,0.262265019,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,warfarin,DB00682
,182,DB00203,10007882,161,13717,68,8870,0.003350982,1.530993796,1.14465358,2.066622072,0.014786062,DB0020310007882_,4.214070278,0.425917064,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,sildenafil,DB00203
,183,DB00559,10007882,124,9535,28,3278,0.048858844,1.522384264,1.001544457,2.388508826,0.12284229,DB0055910007882_,2.096853944,0.420277701,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,bosentan,DB00559
,184,DB00682,10007882,223,19236,159,16205,0.12127325,1.181516411,0.958621232,1.458979851,0.243268393,DB0068210007882_,1.413589948,0.166798708,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,warfarin,DB00682
,185,DB00203,10012174,253,13625,98,8840,9.72625377540241e-06,1.674944157,1.319296924,2.14049338,0.000106103,DB0020310012174_,9.151102577,0.515779826,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,sildenafil,DB00203
,186,DB00559,10012174,183,9476,49,3257,0.128809833,1.283615111,0.929362501,1.802080673,0.253929392,DB0055910012174_,1.370699033,0.249680402,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,bosentan,DB00559
,187,DB00682,10012174,323,19136,192,16172,0.000123153,1.421702459,1.183968318,1.71086845,0.000953063,DB0068210012174_,6.955829079,0.351855068,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,188,DB00203,10016173,632,13246,244,8694,1.03661390141719e-12,1.700010643,1.460467525,1.983702396,4.64180517866284e-11,DB0020310016173_,23.79333269,0.530634512,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,189,DB00559,10016173,570,9089,112,3194,6.56756752359557e-09,1.788379181,1.451745762,2.219030371,1.53447566540186e-07,DB0055910016173_,15.68990691,0.581309724,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,bosentan,DB00559
,190,DB00682,10016173,899,18560,743,15621,0.722657827,1.018362226,0.920866401,1.126446297,0.836750997,DB0068210016173_,0.178228747,0.018195676,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,191,DB00203,10016807,952,12926,358,8580,2.75881408612417e-20,1.765083585,1.556566953,2.004998576,2.91812588546373e-18,DB0020310016807_,40.37559008,0.568198046,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,sildenafil,DB00203
,192,DB00559,10016807,390,9269,156,3150,0.097760051,0.849641427,0.700618927,1.034253677,0.207520529,DB0055910016807_,1.572525009,-0.162940869,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,bosentan,DB00559
,193,DB00682,10016807,714,18745,286,16078,4.75296803989359e-29,2.14119718,1.861104321,2.468839211,9.83714684477188e-27,DB0068210016807_,59.8836318,0.761365103,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,194,DB00203,10018852,40,13838,14,8924,0.0505126,1.842496117,0.980680777,3.668661468,0.125940118,DB0020310018852_,2.071948739,0.611121238,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,sildenafil,DB00203
,196,DB00682,10018852,137,19322,232,16132,3.37868746949673e-11,0.493040283,0.395823778,0.612250077,1.1912649246911e-09,DB0068210018852_,20.54825013,-0.707164397,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,warfarin,DB00682
,197,DB00203,10018884,226,13652,120,8818,0.085644884,1.216433696,0.968970614,1.533402334,0.187754443,DB0020310018884_,1.672620323,0.195923378,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,sildenafil,DB00203
,198,DB00559,10018884,133,9526,39,3267,0.428631111,1.169550798,0.81101519,1.720981421,0.597189057,DB0055910018884_,0.515521537,0.156619742,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,bosentan,DB00559
,199,DB00682,10018884,387,19072,470,15894,5.73323800010597e-08,0.686213766,0.597268664,0.788041073,1.09258634629831e-06,DB0068210018884_,13.72696288,-0.376566087,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,warfarin,DB00682
,200,DB00203,10035664,1085,12793,424,8514,1.54992200188147e-20,1.702997766,1.51555772,1.916184321,1.71535578187177e-18,DB0020310035664_,40.90691116,0.53239009,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sildenafil,DB00203
,201,DB00682,10035664,1171,18288,704,15660,2.85733662682419e-13,1.424309261,1.292899714,1.569937754,1.38315088832549e-11,DB0068210035664_,25.00407187,0.353686967,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,warfarin,DB00682
,202,DB00203,10038435,190,13688,115,8823,0.636742031,1.064962612,0.839028635,1.35662786,0.774232199,DB0020310038435_,0.255883452,0.062939693,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,sildenafil,DB00203
,203,DB00559,10038435,115,9544,41,3265,0.853364083,0.959548586,0.6647729,1.409458978,0.92844119,DB0055910038435_,0.074248239,-0.041292328,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,bosentan,DB00559
,204,DB00682,10038435,224,19235,164,16200,0.182918322,1.150335964,0.935185401,1.417352614,0.327565614,DB0068210038435_,1.116066894,0.140054042,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,warfarin,DB00682
,205,DB00203,10046571,297,13581,72,8866,4.23930693850444e-16,2.692763972,2.072070398,3.538922777,2.95570776866284e-14,DB0020310046571_,31.15245316,0.990568165,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,206,DB00559,10046571,258,9401,32,3274,8.25011039552705e-10,2.807890373,1.934983221,4.200584338,2.33427504570967e-08,DB0055910046571_,17.57297937,1.032433444,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,bosentan,DB00559
,207,DB00682,10046571,504,18955,177,16187,1.47731601077949e-26,2.431494571,2.042072707,2.906024841,2.55468758837756e-24,DB0068210046571_,54.32411229,0.888506118,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,208,DB00203,10066152,233,13645,82,8856,9.18865900845275e-07,1.844141754,1.425820239,2.405409709,1.32997743412544e-05,DB0020310066152_,11.22776349,0.612013995,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,209,DB00559,10066152,187,9472,38,3268,0.002522572,1.697864824,1.189656539,2.479979387,0.011740737,DB0055910066152_,4.444690686,0.529371476,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,bosentan,DB00559
,210,DB00682,10066152,190,19269,98,16266,6.49032043209741e-05,1.636598334,1.274735037,2.11234772,0.000550347,DB0068210066152_,7.504961426,0.492619901,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,211,DB01240,10002034,194,5557,37,1539,0.041626259,1.452017235,1.012195032,2.133601852,0.10897328,DB0124010002034_,2.216652566,0.372953786,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,epoprostenol,DB01240
,212,DB06228,10002034,351,15561,360,15716,0.849655198,0.984710474,0.846171361,1.145826573,0.925344391,DB0622810002034_,0.077589296,-0.015407616,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,rivaroxaban,DB06228
,213,DB01240,10018884,121,5630,31,1545,0.841831147,1.07110656,0.713609442,1.651734766,0.91939469,DB0124010018884_,0.084039771,0.068692282,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,epoprostenol,DB01240
,214,DB06228,10018884,363,15549,289,15787,0.002297229,1.275267852,1.087882365,1.49600845,0.010885643,DB0622810018884_,4.520310481,0.243156237,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,rivaroxaban,DB06228
,215,DB01240,10066152,137,5614,29,1547,0.215135612,1.30173723,0.863086409,2.024421726,0.367579275,DB0124010066152_,1.000816269,0.263699703,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,epoprostenol,DB01240
,216,DB06228,10066152,67,15845,31,16045,0.000236365,2.188508232,1.40877857,3.468624471,0.001656098,DB0622810066152_,6.40329091,0.783220139,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,rivaroxaban,DB06228
,221,DB01164,10028596,101,6423,188,7748,0.000417719,0.648080524,0.502580466,0.831704554,0.002655641,DB0116410028596_,5.931069323,-0.433740325,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,calcium chloride,DB01164
,222,DB01164,10034674,519,6005,665,7271,0.360678033,0.944977706,0.836620551,1.067046234,0.530595892,DB0116410034674_,0.63375458,-0.056593943,NA,10034674,Peritonitis,10021881,Infections and infestations,Infec,calcium chloride,DB01164
,225,DB01012,10011906,335,10297,308,8377,0.135741063,0.884861328,0.753658016,1.039198977,0.263721684,DB0101210011906_,1.33286096,-0.122324337,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,226,DB06210,10011906,177,1283,192,869,3.79055262976658e-05,0.624541671,0.497083025,0.784251531,0.000348617,DB0621010011906_,7.961537289,-0.470737225,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,eltrombopag,DB06210
,228,DB00264,10017822,42,29565,20,24872,0.040566149,1.766633961,1.014037131,3.177326131,0.106772264,DB0026410017822_,2.237057087,0.569076019,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,229,DB00788,10017822,30,9326,31,5030,0.014755451,0.52196173,0.304867099,0.892595738,0.048678635,DB0078810017822_,3.022515057,-0.650161007,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,243,DB00635,10061273,48,33005,31,23763,0.73231614,1.114839771,0.694980723,1.812360242,0.844436487,DB0063510061273_,0.169085753,0.108710691,NA,10061273,Malnutrition,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,249,DB00338,10061818,338,33336,284,21988,0.003001358,0.785014699,0.667797699,0.923282116,0.013515625,DB0033810061818_,4.30390885,-0.242052837,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,250,DB00381,10061818,295,29065,283,22604,0.012839269,0.810689465,0.685664552,0.958582532,0.043456113,DB0038110061818_,3.13600374,-0.209870202,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,251,DB01268,10061818,161,1982,300,2830,0.009789569,0.766318424,0.623344068,0.939461111,0.034992702,DB0126810061818_,3.352615757,-0.266157498,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,252,DB00215,10033295,154,10949,96,5180,0.040514815,0.758919945,0.583085531,0.991977204,0.106674538,DB0021510033295_,2.237972779,-0.275858982,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,253,DB00316,10033295,853,64621,467,36486,0.603733267,1.031300466,0.919489542,1.157817279,0.747337482,DB0031610033295_,0.291238412,0.030820595,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,254,DB00338,10033295,115,33559,92,22180,0.176972709,0.826165813,0.622247474,1.099449157,0.320003279,DB0033810033295_,1.139424037,-0.190959784,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,255,DB00788,10033295,69,9287,72,4989,0.000119938,0.514828493,0.363923059,0.727831884,0.000931063,DB0078810033295_,6.979183845,-0.663921458,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,256,DB01156,10033295,361,13261,222,6106,0.00096654,0.748733411,0.629956867,0.89153556,0.005356985,DB0115610033295_,5.229353987,-0.289372285,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,257,DB00215,10070863,933,10170,605,4671,6.64419021229477e-10,0.708293268,0.634991209,0.790529617,1.90761922152013e-08,DB0021510070863_,17.77482476,-0.344897051,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,258,DB00316,10070863,3602,61872,1862,35091,0.001521185,1.097162545,1.035581377,1.162675571,0.007782863,DB0031610070863_,4.855831039,0.092727343,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,259,DB00338,10070863,236,33438,221,22051,0.000214189,0.704239456,0.583211151,0.850595633,0.001525733,DB0033810070863_,6.485280584,-0.350636844,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,260,DB00788,10070863,218,9138,166,4895,0.00092533,0.703464826,0.570451108,0.868804236,0.005167812,DB0078810070863_,5.265305795,-0.351737402,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,261,DB01156,10070863,1002,12620,697,5631,2.97751074610943e-17,0.641455292,0.578815402,0.711163807,2.37163242307534e-15,DB0115610070863_,33.67519789,-0.444015791,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,277,DB00051,10002855,290,25441,92,11328,0.004420753,1.403581321,1.105218284,1.79629158,0.018513421,DB0005110002855_,3.989259325,0.339027057,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,adalimumab,DB00051
,278,DB00811,10002855,77,2721,73,4083,0.006872978,1.582619585,1.129575283,2.219125272,0.026419453,DB0081110002855_,3.633654671,0.459081439,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ribavirin,DB00811
,279,DB08934,10002855,84,4405,51,6153,2.46302413483812e-06,2.300483981,1.601660691,3.332383583,3.1751147319382e-05,DB0893410002855_,10.3575817,0.833119527,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,sofosbuvir,DB08934
,280,DB00051,10019211,927,24804,266,11154,4.43027779129704e-11,1.56711968,1.363333547,1.806155197,1.5362777274966e-09,DB0005110019211_,20.29390341,0.449239336,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,281,DB00811,10019211,220,2578,273,3883,0.040542797,1.213748991,1.004458785,1.46543685,0.106732176,DB0081110019211_,2.237432606,0.193713909,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ribavirin,DB00811
,282,DB08934,10019211,880,3609,920,5284,9.44972129538485e-11,1.400385517,1.263357077,1.552267228,3.08937716727849e-09,DB0893410019211_,19.59529633,0.336747568,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sofosbuvir,DB08934
,283,DB00051,10028411,200,25531,82,11338,0.560669419,1.083136779,0.832760178,1.419662803,0.71325117,DB0005110028411_,0.337921649,0.079861256,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,284,DB00811,10028411,55,2743,62,4094,0.153525384,1.323940657,0.900753974,1.941573164,0.28887324,DB0081110028411_,1.241767302,0.280612636,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ribavirin,DB00811
,285,DB08934,10028411,66,4423,57,6147,0.009869223,1.609110334,1.109265299,2.34043522,0.035193668,DB0893410028411_,3.346889109,0.475681439,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sofosbuvir,DB08934
,286,DB01164,10000060,221,6303,338,7598,0.007162685,0.78819768,0.66001009,0.939781297,0.027281724,DB0116410000060_,3.60153824,-0.238006357,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,calcium chloride,DB01164
,288,DB00005,10022437,899,127183,256,42163,0.034173299,1.164181485,1.011653077,1.343516157,0.093762543,DB0000510022437_,2.366989829,0.152018252,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,289,DB00005,10048959,3166,124916,872,41547,7.83192349353603e-07,1.207572504,1.119066387,1.304169845,1.15490664251105e-05,DB0000510048959_,11.36890595,0.188612149,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,290,DB00005,10050778,157,127925,26,42393,0.000575721,2.000958144,1.315399214,3.158882646,0.003471627,DB0000510050778_,5.663131984,0.693626138,NA,10050778,Walking aid user,10041244,Social circumstances,SocCi,etanercept,DB00005
,300,DB00563,10037844,1288,45358,299,15049,1.45225472609323e-08,1.429174343,1.257481762,1.628507652,3.14565434489992e-07,DB0056310037844_,14.97207372,0.357096895,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,301,DB00682,10037844,422,19037,292,16072,0.009844297,1.220107934,1.046881386,1.423487074,0.035126225,DB0068210037844_,3.348807286,0.198939325,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,304,DB00563,10040943,97,46549,25,15323,0.295436431,1.27720364,0.815568023,2.070583369,0.461315032,DB0056310040943_,0.773674102,0.244673032,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,305,DB00682,10040943,55,19404,40,16324,0.53648866,1.156740913,0.755434563,1.785171429,0.692783318,DB0068210040943_,0.367038002,0.145606493,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,307,DB00682,10051714,164,19295,78,16286,2.32773128457654e-05,1.774642914,1.346081116,2.356649685,0.000227333,DB0068210051714_,8.389096625,0.573599227,NA,10051714,Calciphylaxis,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,308,DB00563,10003549,506,46140,177,15171,0.47594281,0.939965214,0.789729111,1.122978827,0.641432955,DB0056310003549_,0.444050613,-0.06191241,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,309,DB00563,10016256,1999,44647,525,14823,1.9366336741631e-06,1.264127599,1.145559712,1.396819155,2.5735296322233e-05,DB0056310016256_,10.56764711,0.234382239,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,310,DB00563,10027417,31,46615,23,15325,0.004075743,0.443108519,0.250038617,0.79606163,0.017347732,DB0056310027417_,4.054293517,-0.813940575,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,311,DB00563,10028813,2884,43762,690,14658,1.7434191449347e-15,1.399933473,1.285187325,1.526686191,1.14136418990308e-13,DB0056310028813_,29.801382,0.336424716,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,312,DB00563,10033661,264,46382,246,15102,1.4657878137292e-30,0.349453991,0.292303318,0.417863587,3.39455794571559e-28,DB0056310033661_,63.25020906,-1.051383369,male,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,methotrexate,DB00563
,313,DB00563,10038435,156,46490,117,15231,7.94206925808232e-11,0.43682782,0.341268849,0.560410179,2.63582437435219e-09,DB0056310038435_,19.75406985,-0.828216165,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,methotrexate,DB00563
,314,DB00563,10043071,133,46513,109,15239,7.08859899731366e-12,0.399773592,0.307791511,0.520202855,2.78125056955695e-10,DB0056310043071_,22.00295026,-0.916856913,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,methotrexate,DB00563
,315,DB00563,10043554,189,46457,230,15118,1.1488107650429e-39,0.267422871,0.219240526,0.325878102,4.44066043516952e-37,DB0056310043554_,83.70484533,-1.318924085,male,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,methotrexate,DB00563
,316,DB00563,10047700,1062,45584,353,14995,0.876211049,0.989655022,0.875269493,1.121078683,0.947006884,DB0056310047700_,0.054448917,-0.01039886,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,317,DB00563,10060795,557,46089,182,15166,0.965813329,1.007065849,0.849478781,1.198390041,1,DB0056310060795_,0,0.007041002,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,methotrexate,DB00563
,318,DB00563,10070863,280,46366,218,15130,1.61577256817584e-20,0.419127374,0.349548561,0.503123651,1.76960758143759e-18,DB0056310070863_,40.87577386,-0.86958041,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,319,DB00722,10050953,27,25376,35,25997,0.376084011,0.79031218,0.459935712,1.344313691,0.545851365,DB0072210050953_,0.605408566,-0.235327247,NA,10050953,Lower gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,321,DB01076,10050953,34,25713,38,25545,0.638787418,0.888893423,0.542606134,1.450811599,0.775884443,DB0107610050953_,0.253751683,-0.117777935,NA,10050953,Lower gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,322,DB06228,10050953,163,15749,190,15886,0.181216969,0.865362137,0.696797883,1.073771028,0.325394544,DB0622810050953_,1.122716852,-0.144607204,NA,10050953,Lower gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,324,DB00316,10019075,51,65423,35,36918,0.370969172,0.822273414,0.524349637,1.302988396,0.540636764,DB0031610019075_,0.615007641,-0.195682319,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,325,DB00451,10019075,57,47214,21,15398,0.601069407,0.885202412,0.528230538,1.537853463,0.745334479,DB0045110019075_,0.293922197,-0.121938946,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,331,DB00316,10028813,4192,61282,1584,35369,8.04794442443154e-47,1.527404171,1.439102881,1.621691565,4.23080438392366e-44,DB0031610028813_,99.87135196,0.423569674,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,332,DB00451,10028813,3252,44019,635,14784,7.75416359048277e-38,1.720012392,1.575989261,1.879423647,2.79202999966904e-35,DB0045110028813_,79.56370933,0.542331496,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,333,DB00635,10028813,1850,31203,806,22988,5.57181447836294e-36,1.690973586,1.553162596,1.842392599,1.8193185535872e-33,DB0063510028813_,75.38684606,0.525304449,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,334,DB00722,10028813,1579,23824,1010,25022,5.63075038038316e-34,1.641950426,1.51331983,1.782221116,1.60874210596056e-31,DB0072210028813_,70.90468531,0.495884819,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,335,DB00813,10028813,617,9955,290,9878,3.15320324243059e-26,2.111043709,1.827954743,2.442637653,5.2959710688363e-24,DB0081310028813_,53.59509588,0.747182474,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,336,DB00999,10028813,1415,20015,475,11764,9.53559104173087e-27,1.750873696,1.572907505,1.951673006,1.67654187646753e-24,DB0099910028813_,54.74530897,0.560114918,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,337,DB08895,10028813,1203,26911,161,6485,1.65611398653505e-13,1.800544623,1.522691158,2.14068289,8.26014347933088e-12,DB0889510028813_,25.51957916,0.588089187,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,338,DB00374,10040070,84,17632,37,5687,0.136672669,0.732260401,0.49119576,1.110517658,0.26505634,DB0037410040070_,1.327812872,-0.311619089,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,treprostinil,DB00374
,339,DB06403,10040070,54,21417,21,6640,0.413867194,0.797237397,0.473203361,1.390746183,0.583203731,DB0640310040070_,0.539218701,-0.226602782,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,340,DB00005,10002855,860,127222,198,42221,1.99368115013648e-06,1.441416531,1.233190704,1.691554737,2.64066057099206e-05,DB0000510002855_,10.54189636,0.365626332,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,341,DB00005,10016825,133,127949,47,42372,0.730038961,0.937115766,0.667165155,1.336604883,0.842888988,DB0000510016825_,0.170920016,-0.064948455,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,etanercept,DB00005
,342,DB00005,10023232,2782,125300,846,41573,0.028274595,1.091054784,1.0090242,1.180642674,0.080870265,DB0000510023232_,2.514909075,0.08714492,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,353,DB00997,10016288,477,4854,528,2986,3.15663391574198e-18,0.555765866,0.485940565,0.635531506,2.77498737375512e-16,DB0099710016288_,35.82071529,-0.587408178,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,doxorubicin,DB00997
,361,DB00997,10018884,57,5274,32,3482,0.514332654,1.175961238,0.748073923,1.878161502,0.674292815,DB0099710018884_,0.394090818,0.162085888,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,doxorubicin,DB00997
,369,DB00997,10025197,25,5306,33,3481,0.009958058,0.49703912,0.282845529,0.863378694,0.035445536,DB0099710025197_,3.339757969,-0.699086543,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,doxorubicin,DB00997
,385,DB00997,10043071,64,5267,46,3468,0.69516161,0.916099654,0.615847986,1.372140508,0.816560818,DB0099710043071_,0.202653883,-0.087630127,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,doxorubicin,DB00997
,389,DB00997,10047895,71,5260,53,3461,0.518052972,0.881466497,0.607208355,1.286406942,0.677438866,DB0099710047895_,0.389435965,-0.126168284,NA,10047895,Weight decreased,10022891,Investigations,Inv,doxorubicin,DB00997
,395,DB00060,10016256,559,8949,119,2346,0.044945981,1.231428637,1.003058318,1.52175123,0.115473083,DB0006010016256_,2.158717827,0.208174989,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,396,DB00060,10028334,164,9344,39,2426,0.662542316,1.091777126,0.763529685,1.595213478,0.794259089,DB0006010028334_,0.230345562,0.08780676,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,397,DB00398,10008479,20,707,35,1503,0.558734476,1.214657892,0.659371707,2.180997269,0.711616228,DB0039810008479_,0.340216518,0.194462467,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,sorafenib,DB00398
,414,DB00541,10070863,47,3087,63,4234,0.922717596,1.023231091,0.683914169,1.521561686,0.966145438,DB0054110070863_,0.034440899,0.022965357,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,vincristine,DB00541
,415,DB00635,10070863,242,32811,278,23516,9.56353257822724e-08,0.623918857,0.522526209,0.74453052,1.73603213963193e-06,DB0063510070863_,13.26390843,-0.471734956,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,422,DB06605,10028596,85,13988,91,12942,0.363902785,0.864223649,0.634712436,1.175724728,0.533488648,DB0660510028596_,0.628317487,-0.14592369,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,apixaban,DB06605
,423,DB00005,10001760,1359,126723,95,42324,4.29436472518403e-76,4.777856058,3.877317057,5.947917914,5.50621350251035e-73,DB0000510001760_,166.3828346,1.563991923,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,427,DB00005,10019974,880,127202,218,42201,8.61173667069776e-05,1.339209952,1.152847534,1.561150388,0.000702217,DB0000510019974_,7.261268754,0.292079852,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,etanercept,DB00005
,428,DB00005,10067152,235,127847,46,42373,0.000689641,1.693129552,1.229825498,2.376427137,0.004042644,DB0000510067152_,5.510856371,0.526578622,NA,10067152,Oral herpes,10021881,Infections and infestations,Infec,etanercept,DB00005
,429,DB00482,10000087,117,8142,29,3042,0.04903857,1.507376319,0.994247939,2.353873445,0.123179773,DB0048210000087_,2.094110418,0.410370603,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,celecoxib,DB00482
,430,DB00482,10013709,734,7525,224,2847,0.006963159,1.239686872,1.059150694,1.455299707,0.026684157,DB0048210013709_,3.623685253,0.214858825,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,431,DB00482,10016256,411,7848,148,2923,0.769731448,1.03433328,0.850770334,1.262786638,0.873904099,DB0048210016256_,0.134784636,0.033757045,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,432,DB00482,10022004,50,8209,16,3055,0.678129867,1.162957206,0.650156093,2.191363133,0.805000469,DB0048210022004_,0.216912419,0.150966076,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,433,DB00482,10028813,432,7827,127,2944,0.016746867,1.27939423,1.042400603,1.579111594,0.053727744,DB0048210028813_,2.92382577,0.246386708,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,celecoxib,DB00482
,434,DB00482,10037087,177,8082,39,3032,0.001959299,1.702592933,1.194679669,2.480610421,0.009575194,DB0048210037087_,4.64857953,0.532152344,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,celecoxib,DB00482
,435,DB00482,10037844,287,7972,78,2993,0.011874482,1.381339647,1.067936222,1.804247358,0.040832126,DB0048210037844_,3.19828611,0.323053787,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,celecoxib,DB00482
,436,DB00482,10053762,217,8042,64,3007,0.103028317,1.267751191,0.951941196,1.708275413,0.215535781,DB0048210053762_,1.534628345,0.237244615,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,celecoxib,DB00482
,437,DB00374,10000060,330,17386,113,5611,0.577114761,0.942485837,0.757253323,1.180094271,0.726263298,DB0037410000060_,0.319842661,-0.059234387,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,438,DB00374,10013968,3650,14066,1130,4594,0.162677878,1.054958514,0.978657227,1.137712665,0.300956365,DB0037410013968_,1.200789992,0.053501443,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,439,DB00374,10016256,1335,16381,391,5333,0.0806943,1.111560209,0.988035989,1.25263509,0.179508741,DB0037410016256_,1.717531373,0.105764622,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,441,DB00374,10038687,117,17599,66,5658,0.000502541,0.569939894,0.417278873,0.784043297,0.003103689,DB0037410038687_,5.775163839,-0.562224372,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,442,DB00374,10055798,119,17597,38,5686,1,1.011887587,0.696062303,1.500944071,1,DB0037410055798_,0,0.011817485,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,treprostinil,DB00374
,443,DB00526,10008479,28,1570,44,1850,0.282077739,0.749917313,0.447296787,1.238310908,0.446073662,DB0052610008479_,0.807271179,-0.287792328,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,oxaliplatin,DB00526
,444,DB00544,10008479,47,2388,59,2594,0.492490634,0.865354496,0.574580096,1.296979268,0.655382559,DB0054410008479_,0.422536154,-0.144616033,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,fluorouracil,DB00544
,445,DB00650,10008479,32,2099,37,1977,0.466445651,0.814638616,0.489207896,1.349942837,0.633177056,DB0065010008479_,0.457005186,-0.20501068,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,leucovorin,DB00650
,451,DB05259,10000087,53,11217,17,2711,0.292525297,0.75351087,0.428643111,1.390536468,0.458130154,DB0525910000087_,0.780601956,-0.283011836,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,glatiramer,DB05259
,453,DB05259,10048959,93,11177,23,2705,0.906468467,0.97858194,0.61326425,1.622313902,0.958224861,DB0525910048959_,0.042672809,-0.021650755,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,454,DB00005,10003285,1035,127047,333,42086,0.660346841,1.029615324,0.908652437,1.169025704,0.792639361,DB0000510003285_,0.232386939,0.029185261,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,455,DB00005,10016326,133,127949,37,42382,0.375661206,1.190673141,0.821562702,1.764045158,0.545493733,DB0000510016326_,0.606063962,0.174518812,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,456,DB00005,10019211,4784,123298,1095,41324,3.39716915255542e-31,1.464225842,1.36958434,1.566541635,8.22991623731975e-29,DB0000510019211_,64.66719186,0.381326667,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,457,DB00005,10022000,1781,126301,596,41823,0.829764509,0.989523212,0.900766181,1.08823034,0.91066932,DB0000510022000_,0.093575433,-0.010532056,NA,10022000,Influenza,10021881,Infections and infestations,Infec,etanercept,DB00005
,458,DB00005,10022004,587,127495,195,42224,0.966943265,0.996941578,0.846082023,1.178822627,1,DB0000510022004_,0,-0.003063108,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,459,DB00005,10028810,4067,124015,1424,40995,0.068055621,0.944101989,0.887657154,1.004568259,0.157787951,DB0000510028810_,1.846503227,-0.057521079,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,etanercept,DB00005
,460,DB00005,10068319,1400,126682,356,42063,5.23282910272018e-06,1.305743788,1.160888045,1.471796154,6.15826787396463e-05,DB0000510068319_,9.695129916,0.266772831,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,461,DB00005,10013786,449,127633,121,42298,0.046490966,1.229744735,1.003614376,1.516444241,0.118481195,DB0000510013786_,2.133001024,0.206806616,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,462,DB00005,10037087,1913,126169,537,41882,0.000586615,1.182533542,1.073295673,1.304562057,0.003528415,DB0000510037087_,5.646906635,0.167659206,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,463,DB00005,10037153,3647,124435,2439,39980,2.62505891779198e-155,0.480413859,0.455724215,0.506544588,1.5333260812036e-151,DB0000510037153_,347.2629098,-0.733107341,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,465,DB00374,10011906,1385,16331,605,5119,2.30548993379238e-10,0.71758512,0.648388326,0.794864491,7.11648110980168e-09,DB0037410011906_,18.76085246,-0.331863704,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,466,DB00820,10011906,1041,10874,564,5252,0.03910285,0.891480923,0.799605642,0.994636241,0.103841019,DB0082010011906_,2.264894214,-0.11487124,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,471,DB00060,10022061,150,9358,35,2430,0.646847399,1.112865039,0.763636105,1.661898859,0.782237168,DB0006010022061_,0.2455973,0.106937806,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,472,DB00068,10046571,61,2173,11,654,0.154426812,1.668681926,0.863762334,3.538687605,0.290038852,DB0006810046571_,1.237740394,0.512034049,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,interferon beta-1b,DB00068
,474,DB00068,10022437,49,2185,8,657,0.113675909,1.841300303,0.859128039,4.52578111,0.23164903,DB0006810022437_,1.462531853,0.610472009,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,interferon beta-1b,DB00068
,476,DB01137,10003549,201,7571,174,5419,0.071224414,0.826839892,0.669464225,1.021990421,0.163404465,DB0113710003549_,1.811526772,-0.190144204,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,479,DB01137,10033775,89,7683,51,5542,0.197584737,1.258774603,0.88074844,1.815920446,0.346057852,DB0113710033775_,1.061149317,0.230138711,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,481,DB00005,10042209,749,127333,150,42269,3.59689747712191e-09,1.657499551,1.388756326,1.989438993,8.91088126165405e-08,DB0000510042209_,16.2334076,0.505310172,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,482,DB00005,10067723,313,127769,217,42202,5.27988449164439e-16,0.476411354,0.399260335,0.569333706,3.64735253253279e-14,DB0000510067723_,30.94218973,-0.741473609,NA,10067723,Skin plaque,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,483,DB00005,10067868,109,127973,27,42392,0.197147506,1.33728021,0.870802819,2.121057538,0.345594864,DB0000510067868_,1.062488104,0.290637858,NA,10067868,Skin mass,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,484,DB00060,10022004,744,8764,176,2289,0.269936146,1.104078221,0.92929841,1.317152165,0.432572572,DB0006010022004_,0.838005171,0.099010798,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,487,DB08908,10035664,188,10485,90,3189,0.000744952,0.635356358,0.489999765,0.828881124,0.004310164,DB0890810035664_,5.44677937,-0.453569244,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,dimethyl fumarate,DB08908
,488,DB00005,10013709,12014,116068,4060,38359,0.242245777,0.977948778,0.941942184,1.015475313,0.400505095,DB0000510013709_,0.91502879,-0.022297984,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,492,DB00331,10005483,103,24843,165,20587,1.33762297441387e-07,0.517313929,0.400175335,0.666142602,2.36843515543743e-06,DB0033110005483_,12.95328109,-0.659105377,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,metformin,DB00331
,496,DB00005,10003246,1511,126571,537,41882,0.157379391,0.931065874,0.842684854,1.029977785,0.294041106,DB0000510003246_,1.224035704,-0.071425248,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,497,DB00005,10028391,1443,126639,506,41913,0.268446627,0.943832689,0.851817313,1.047153839,0.430942554,DB0000510028391_,0.841780483,-0.057806364,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,498,DB00005,10028836,714,127368,259,42160,0.206308468,0.912502849,0.790123333,1.05648278,0.356836623,DB0000510028836_,1.030477241,-0.091564072,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,499,DB00005,10061218,776,127306,201,42218,0.001596798,1.28029515,1.094519875,1.50329463,0.008084721,DB0000510061218_,4.817779324,0.247090637,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,500,DB00005,10028813,3142,124940,592,41827,1.53632215637221e-41,1.776883315,1.625683582,1.944428719,6.40987744130849e-39,DB0000510028813_,87.94297848,0.574860883,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,501,DB00005,10054266,585,127497,212,42207,0.267487263,0.913482224,0.77903414,1.074449978,0.429795481,DB0000510054266_,0.844445808,-0.090491363,NA,10054266,Injection site discomfort,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,502,DB00005,10043248,71,128011,21,42398,0.718327402,1.119789495,0.679978637,1.919180477,0.833618427,DB0000510043248_,0.181979503,0.113140717,NA,10043248,Tendon rupture,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,503,DB00295,10002034,164,14499,133,9469,0.073112943,0.805316448,0.635773788,1.021576792,0.166709354,DB0029510002034_,1.791503375,-0.216519976,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,morphine,DB00295
,504,DB00635,10002034,559,32494,432,23362,0.269498302,0.930327092,0.81816188,1.058458359,0.432055313,DB0063510002034_,0.83920166,-0.072219043,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,505,DB00682,10002034,536,18923,629,15735,8.77484176514363e-09,0.708597262,0.629035183,0.797982666,1.9986717140104e-07,DB0068210002034_,15.42561283,-0.344467951,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,warfarin,DB00682
,506,DB00295,10009887,44,14619,30,9572,0.905412704,0.960293655,0.589800083,1.583264776,0.957832006,DB0029510009887_,0.043082876,-0.040516151,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,507,DB00635,10009887,162,32891,172,23622,0.000440929,0.676452822,0.542033619,0.84385254,0.002780855,DB0063510009887_,5.884996833,-0.390892572,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,508,DB00682,10009887,38,19421,24,16340,0.308033213,1.332136529,0.778270766,2.322600245,0.47525331,DB0068210009887_,0.743907333,0.286784066,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,515,DB00635,10018852,37,33016,40,23754,0.08267833,0.665527134,0.413733917,1.067976668,0.18286002,DB0063510018852_,1.699034335,-0.407175869,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,prednisone,DB00635
,517,DB00295,10047895,194,14469,150,9452,0.133723515,0.844892055,0.678100715,1.054376488,0.260942828,DB0029510047895_,1.343453946,-0.168546405,NA,10047895,Weight decreased,10022891,Investigations,Inv,morphine,DB00295
,518,DB00635,10047895,557,32496,480,23314,0.003826715,0.832538793,0.73467704,0.943714542,0.016458348,DB0063510047895_,4.106922455,-0.183275461,NA,10047895,Weight decreased,10022891,Investigations,Inv,prednisone,DB00635
,519,DB00682,10047895,504,18955,315,16049,2.74859300196207e-05,1.354689349,1.172552,1.566982532,0.000262668,DB0068210047895_,8.244620599,0.303572165,NA,10047895,Weight decreased,10022891,Investigations,Inv,warfarin,DB00682
,520,DB01240,10047895,453,5298,104,1472,0.096233677,1.210173174,0.967752042,1.524350727,0.205067062,DB0124010047895_,1.584418224,0.190763468,NA,10047895,Weight decreased,10022891,Investigations,Inv,epoprostenol,DB01240
,521,DB00722,10067482,77,25326,39,25993,0.000260373,2.026317288,1.360773923,3.061224241,0.001796303,DB0072210067482_,6.322024615,0.706220002,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,522,DB01076,10067482,70,25677,81,25502,0.370465305,0.858311016,0.614021281,1.197274793,0.540142031,DB0107610067482_,0.615923153,-0.152788756,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,523,DB01255,10067482,79,2054,74,1504,0.155505087,0.781764454,0.557902331,1.096390103,0.291481938,DB0125510067482_,1.232777239,-0.246201793,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,lisdexamfetamine,DB01255
,524,DB00722,10069327,136,25267,125,25907,0.385550161,1.115555594,0.867980992,1.434702549,0.555660053,DB0072210069327_,0.587598588,0.109352572,NA,10069327,Product quality issue,10077536,Product issues,Prod,lisinopril,DB00722
,525,DB01076,10069327,126,25621,135,25448,0.576598877,0.927058467,0.720885628,1.191426894,0.72583997,DB0107610069327_,0.320425716,-0.075738645,NA,10069327,Product quality issue,10077536,Product issues,Prod,atorvastatin,DB01076
,526,DB01255,10069327,283,1850,234,1344,0.179600645,0.878646946,0.725806355,1.064318644,0.323369268,DB0125510069327_,1.128960364,-0.129372116,NA,10069327,Product quality issue,10077536,Product issues,Prod,lisdexamfetamine,DB01255
,530,DB00230,10002855,540,19134,152,8499,3.95023138744248e-07,1.577995731,1.313196948,1.905311446,6.25652304530304e-06,DB0023010002855_,11.98188595,0.456155517,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,531,DB05676,10002855,422,46707,211,25118,0.402650657,1.075561349,0.908924317,1.275866673,0.572430771,DB0567610002855_,0.557863475,0.072842711,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,534,DB00230,10012378,509,19165,157,8494,6.09997757149721e-05,1.436886357,1.196837239,1.732805799,0.000523125,DB0023010012378_,7.555689506,0.36247852,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,535,DB05676,10012378,1626,45503,852,24477,0.548459864,1.026595557,0.942940969,1.118245304,0.702872554,DB0567610012378_,0.352579693,0.026248043,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,538,DB00230,10037162,57,19617,12,8639,0.017925525,2.091774477,1.109075567,4.285646727,0.056696038,DB0023010037162_,2.87005094,0.738012738,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,539,DB05676,10037162,1716,45413,709,24620,1.26387692536917e-09,1.312131359,1.199817555,1.436077119,3.44616234266894e-08,DB0567610037162_,17.1834195,0.271652807,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,540,DB00005,10013573,1641,126441,447,41972,0.000198695,1.21862474,1.096282879,1.356743007,0.001432449,DB0000510013573_,6.548369984,0.19772296,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,541,DB00005,10050256,181,127901,64,42355,0.657390817,0.936540799,0.700448691,1.26607822,0.790589419,DB0000510050256_,0.234976512,-0.065562193,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,543,DB00230,10048959,541,19133,201,8450,0.039396737,1.188685813,1.007027834,1.407589124,0.104437494,DB0023010048959_,2.259166535,0.172848338,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,544,DB00108,10046735,87,10107,16,3279,0.037648244,1.763938807,1.025669958,3.226869063,0.100905894,DB0010810046735_,2.293566943,0.567549267,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,natalizumab,DB00108
,545,DB00126,10003988,263,9908,113,5832,0.005745296,1.369937145,1.092078361,1.727489553,0.022872411,DB0012610003988_,3.777823858,0.314764859,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,546,DB00316,10003988,1498,63976,727,36226,0.000691321,1.166786275,1.066119898,1.277804384,0.004049782,DB0031610003988_,5.509092238,0.154253196,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,547,DB00327,10003988,161,5977,110,4152,0.950114388,1.01673307,0.790169242,1.312162611,0.988407804,DB0032710003988_,0.011659909,0.016594615,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydromorphone,DB00327
,548,DB00404,10003988,439,19453,129,9733,4.54309480254095e-08,1.702659393,1.393889489,2.091627475,8.84557384331769e-07,DB0040410003988_,13.93817845,0.532191378,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,549,DB00425,10003988,269,12426,140,7344,0.234596586,1.135618014,0.920382576,1.4060392,0.391449575,DB0042510003988_,0.937898573,0.127177009,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,550,DB00497,10003988,456,18811,295,16080,0.000211997,1.321334847,1.137046518,1.537334779,0.001512581,DB0049710003988_,6.493937532,0.278642473,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,551,DB00737,10003988,82,2719,25,907,0.820675058,1.094110895,0.686855455,1.799113888,0.904519726,DB0073710003988_,0.100351166,0.089942065,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,meclizine,DB00737
,552,DB00813,10003988,216,10356,121,10047,1.17901122197423e-06,1.731805087,1.377429873,2.185714005,1.65635007854584e-05,DB0081310003988_,11.00830903,0.549164268,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fentanyl,DB00813
,553,DB00996,10003988,826,38127,372,22053,6.25096998210248e-05,1.284317106,1.133677657,1.45710067,0.000533463,DB0099610003988_,7.536119979,0.250227142,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,554,DB01050,10003988,405,17703,170,9201,0.020752599,1.23815735,1.030708627,1.492666966,0.063635332,DB0105010003988_,2.754586421,0.213624266,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,555,DB01234,10003988,694,30931,571,32317,2.92564661022417e-05,1.269864863,1.133863149,1.422660431,0.000277569,DB0123410003988_,8.18943932,0.238910488,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,556,DB08910,10003988,275,16469,276,17212,0.667533947,1.041340962,0.87671158,1.236846146,0.798095511,DB0891010003988_,0.225527001,0.040509269,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pomalidomide,DB08910
,557,DB00126,10006002,56,10115,15,5930,0.006265138,2.188599658,1.219559298,4.170804484,0.024513121,DB0012610006002_,3.708546773,0.783261914,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,558,DB00316,10006002,336,65138,132,36821,0.000347406,1.438881296,1.172521506,1.774190658,0.002280328,DB0031610006002_,6.083435975,0.363865934,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,560,DB00404,10006002,101,19791,30,9832,0.011915882,1.672504755,1.102218741,2.607114345,0.040936995,DB0040410006002_,3.195721097,0.514322356,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,561,DB00425,10006002,74,12621,23,7461,0.005966831,1.901928142,1.176286095,3.185555356,0.023561653,DB0042510006002_,3.748134778,0.642868183,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,562,DB00497,10006002,116,19151,76,16299,0.081421401,1.299002978,0.963642118,1.759688142,0.180749253,DB0049710006002_,1.710644553,0.26159703,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,564,DB00813,10006002,36,10536,29,10139,0.535006551,1.194592194,0.711604912,2.021472102,0.691531912,DB0081310006002_,0.36884598,0.177804867,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fentanyl,DB00813
,565,DB00996,10006002,137,38816,78,22347,1,1.011193855,0.759864452,1.35371396,1,DB0099610006002_,0,0.011131668,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,566,DB01050,10006002,80,18028,37,9334,0.625605219,1.119449114,0.748543287,1.702086753,0.76522501,DB0105010006002_,0.267585358,0.112836702,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,567,DB01234,10006002,190,31435,120,32768,1.78003016170723e-05,1.65044968,1.305684554,2.092961474,0.000180197,DB0123410006002_,8.621461106,0.501047784,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,568,DB08910,10006002,74,16670,51,17437,0.02470891,1.51771278,1.047439365,2.214183229,0.072855875,DB0891010006002_,2.619272108,0.417204452,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pomalidomide,DB08910
,569,DB00126,10008479,149,10022,72,5873,0.206287137,1.21265957,0.907538871,1.6330243,0.356833102,DB0012610008479_,1.030487107,0.192815939,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,570,DB00327,10008479,80,6058,61,4201,0.60533636,0.909469306,0.642009201,1.293817079,0.748483687,DB0032710008479_,0.289705869,-0.09489403,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,571,DB00404,10008479,271,19621,112,9750,0.11299489,1.202330201,0.959902138,1.514298589,0.2305508,DB0040410008479_,1.467284052,0.184261508,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,572,DB00425,10008479,179,12516,81,7403,0.052342072,1.307087387,0.998199134,1.72389662,0.129424343,DB0042510008479_,2.044658789,0.267801293,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,573,DB00497,10008479,227,19040,199,16176,0.769272367,0.969109216,0.796669222,1.179716843,0.873663127,DB0049710008479_,0.135060416,-0.031377963,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,574,DB00737,10008479,68,2733,9,923,0.004961007,2.551377299,1.261203469,5.841173384,0.020338464,DB0073710008479_,3.895241384,0.93663333,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,meclizine,DB00737
,575,DB00813,10008479,109,10463,58,10110,0.00023804,1.815845786,1.307028845,2.545239738,0.00166606,DB0081310008479_,6.397293575,0.596551357,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,576,DB00996,10008479,499,38454,232,22193,0.00680615,1.241359173,1.059190758,1.458203799,0.026210483,DB0099610008479_,3.641595851,0.216206886,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,577,DB01050,10008479,227,17881,123,9248,0.691343794,0.95450639,0.761937027,1.200399611,0.813901179,DB0105010008479_,0.205916323,-0.046560941,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,578,DB01234,10008479,286,31339,284,32604,0.584616931,1.047708471,0.885266231,1.23994839,0.732355822,DB0123410008479_,0.311488787,0.04660537,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,579,DB08910,10008479,97,16647,121,17367,0.197077406,0.836330497,0.633013629,1.102496515,0.345506545,DB0891010008479_,1.062743692,-0.178731413,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,580,DB00126,10013968,460,9711,222,5723,0.016711316,1.221089908,1.034565339,1.444669457,0.053659849,DB0012610013968_,2.925090254,0.199743827,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,581,DB00316,10013968,2463,63011,1334,35619,0.221503552,1.04369846,0.974744948,1.117885755,0.375374455,DB0031610013968_,0.979831204,0.042770616,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,582,DB00327,10013968,236,5902,149,4113,0.369609832,1.103803709,0.891693087,1.369718399,0.539238721,DB0032710013968_,0.617596909,0.098762133,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydromorphone,DB00327
,583,DB00404,10013968,812,19080,308,9554,3.88892399474936e-05,1.320122461,1.153651918,1.513602232,0.000356169,DB0040410013968_,7.940106549,0.277724506,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,584,DB00425,10013968,504,12191,258,7226,0.061077878,1.15792197,0.991685338,1.354515947,0.145432741,DB0042510013968_,1.928041561,0.146626994,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,585,DB00497,10013968,613,18654,519,15856,0.951691467,1.00395621,0.889962472,1.132860114,0.989813911,DB0049710013968_,0.010238322,0.003948404,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,586,DB00737,10013968,161,2640,34,898,0.013444438,1.610585098,1.09723925,2.424453892,0.045057638,DB0073710013968_,3.099812758,0.476597528,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,meclizine,DB00737
,587,DB00813,10013968,282,10290,199,9969,0.000741164,1.372853126,1.138480131,1.657939502,0.00429108,DB0081310013968_,5.451216823,0.316891148,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,588,DB00996,10013968,1399,37554,656,21769,8.49173447834842e-06,1.236181686,1.124181527,1.360484832,9.41397050878905e-05,DB0099610013968_,9.270730655,0.212027343,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,589,DB01050,10013968,576,17532,269,9102,0.161476215,1.111677547,0.957964514,1.292529593,0.29944986,DB0105010013968_,1.205808287,0.105870178,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,590,DB01234,10013968,1050,30575,999,31889,0.041024819,1.096213152,1.002865228,1.198317844,0.107706523,DB0123410013968_,2.228345129,0.091861651,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,591,DB08910,10013968,481,16263,532,16956,0.371724692,0.942643045,0.829992662,1.070456059,0.541392633,DB0891010013968_,0.61361051,-0.059067599,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,592,DB00126,10016256,897,9274,436,5509,0.000901166,1.222080179,1.08337646,1.380073038,0.005056496,DB0012610016256_,5.287081612,0.200554472,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,593,DB00316,10016256,4101,61373,2061,34892,8.68620606654446e-06,1.131278292,1.070889416,1.195244341,9.60121641964344e-05,DB0031610016256_,9.251035664,0.123348225,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,594,DB00327,10016256,311,5827,175,4087,0.023326798,1.246443824,1.027753862,1.515465098,0.069636386,DB0032710016256_,2.664468056,0.220294556,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,595,DB00404,10016256,1398,18494,487,9375,1.3221415563197e-12,1.455168851,1.307629032,1.621424723,5.85058019433587e-11,DB0040410016256_,23.56189519,0.375121943,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,596,DB00425,10016256,875,11820,495,6989,0.451557056,1.045204499,0.931259754,1.174028084,0.619215937,DB0042510016256_,0.479301218,0.044212559,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,597,DB00497,10016256,1113,18154,826,15549,0.002498389,1.154099595,1.0510985,1.267560284,0.011652942,DB0049710016256_,4.452196583,0.143320468,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,598,DB00737,10016256,247,2554,48,884,0.000252356,1.780853535,1.28921062,2.503152832,0.001749886,DB0073710016256_,6.348204455,0.577092763,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,meclizine,DB00737
,599,DB00813,10016256,428,10144,291,9877,2.90306733015535e-06,1.432046489,1.227746606,1.672183474,3.68351532707098e-05,DB0081310016256_,10.20905792,0.359104532,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,600,DB00996,10016256,2463,36490,1164,21261,8.26489328209393e-09,1.232850016,1.147043186,1.325761018,1.89400802022527e-07,DB0099610016256_,15.47940042,0.209328575,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,601,DB01050,10016256,1078,17030,515,8856,0.127338244,1.088521693,0.975977454,1.21518651,0.251897328,DB0105010016256_,1.378733702,0.084820531,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,602,DB01234,10016256,2486,29139,2247,30641,5.71049898570083e-07,1.163388405,1.095986348,1.235031552,8.71916734470789e-06,DB0123410016256_,11.64998681,0.151336786,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,603,DB08910,10016256,934,15810,1012,16476,0.413853847,0.961794103,0.87667789,1.055142192,0.583200556,DB0891010016256_,0.539224145,-0.038954881,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,604,DB00126,10028813,674,9497,206,5739,1.53737999664044e-18,1.977080416,1.682926482,2.330395935,1.38866093510976e-16,DB0012610028813_,36.51302156,0.681621219,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,605,DB00327,10028813,511,5627,262,4000,2.83907465653424e-05,1.38640093,1.185481014,1.624248774,0.000270332,DB0032710028813_,8.21586068,0.32671113,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,hydromorphone,DB00327
,606,DB00404,10028813,1284,18608,360,9502,7.46814688840337e-25,1.821250085,1.614703917,2.058169684,1.12816230437749e-22,DB0040410028813_,50.53628202,0.599523125,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,607,DB00425,10028813,875,11820,320,7164,9.32926033649903e-15,1.657239705,1.451354883,1.895891709,5.53543133058413e-13,DB0042510028813_,28.22243672,0.50515339,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,608,DB00497,10028813,1257,18010,751,15624,1.91598427551411e-15,1.452004402,1.3220734,1.595501854,1.24196415984928e-13,DB0049710028813_,29.71691208,0.372944948,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,609,DB00737,10028813,222,2579,54,878,0.030290848,1.399421183,1.024115658,1.940110815,0.085314218,DB0073710028813_,2.461414161,0.33605871,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,meclizine,DB00737
,610,DB00996,10028813,2271,36682,795,21630,1.4379809124785e-37,1.684416556,1.550279107,1.831605861,5.10774706547263e-35,DB0099610028813_,78.95971984,0.521419246,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,611,DB01050,10028813,1205,16903,400,8971,3.16995110202871e-16,1.598810511,1.422411194,1.799971856,2.24588045058827e-14,DB0105010028813_,31.42709367,0.469259922,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,612,DB01234,10028813,1619,30006,949,31939,4.21061105581728e-48,1.815874498,1.67239216,1.972593371,2.35480662983313e-45,DB0123410028813_,102.7598706,0.596567169,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,613,DB08910,10028813,393,16351,207,17281,1.86547548228159e-16,2.006480058,1.68896423,2.389294174,1.35640451042245e-14,DB0891010028813_,31.93135385,0.696381972,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,614,DB00126,10033425,303,9868,108,5837,4.75986619885179e-06,1.65945843,1.324533214,2.09196645,5.66507054728636e-05,DB0012610033425_,9.778606117,0.506491302,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,615,DB00316,10033425,1525,63949,614,36339,3.52411210607466e-13,1.411364591,1.283092023,1.553834827,1.67962441900585e-11,DB0031610033425_,24.80986581,0.344557032,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,616,DB00327,10033425,118,6020,62,4200,0.078596086,1.327795919,0.965642115,1.840926694,0.175970879,DB0032710033425_,1.737436758,0.283520364,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,hydromorphone,DB00327
,617,DB00404,10033425,451,19441,138,9724,2.1256488958438e-07,1.634621276,1.345727307,1.995721754,3.58273044099098e-06,DB0040410033425_,12.53938536,0.491411142,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,618,DB00425,10033425,287,12408,110,7374,7.92986425868181e-05,1.550534621,1.237900979,1.953521423,0.000654021,DB0042510033425_,7.332371148,0.438599788,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,619,DB00497,10033425,388,18879,225,16150,3.63320262478038e-06,1.475152591,1.246758653,1.748738193,4.47091437230114e-05,DB0049710033425_,10.01533252,0.388761436,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,620,DB00737,10033425,80,2721,19,913,0.196560078,1.412638651,0.842850122,2.481927217,0.34480657,DB0073710033425_,1.064771685,0.345459339,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,meclizine,DB00737
,621,DB00813,10033425,135,10437,65,10103,2.30106777943506e-06,2.010383298,1.482728865,2.74965028,2.99423596942824e-05,DB0081310033425_,10.41623637,0.6983254,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,fentanyl,DB00813
,622,DB00996,10033425,1025,37928,407,22018,6.11154308063601e-11,1.461991014,1.300486855,1.645913076,2.06613388906132e-09,DB0099610033425_,19.99758666,0.379799215,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,623,DB01050,10033425,470,17638,172,9199,6.1315459010311e-05,1.425132904,1.191931468,1.710317829,0.000525147,DB0105010033425_,7.551831902,0.354265076,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,624,DB01234,10033425,449,31176,315,32573,6.53085867037531e-08,1.489250223,1.285457761,1.727004686,1.2314463425453e-06,DB0123410033425_,13.60732119,0.398272787,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,625,DB08910,10033425,160,16584,110,17378,0.000747026,1.524156396,1.1870286,1.962966131,0.004321208,DB0891010033425_,5.444220201,0.421441074,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,pomalidomide,DB08910
,626,DB00126,10039117,33,10138,17,5928,0.769661747,1.135078471,0.613725043,2.174723032,0.873852947,DB0012610039117_,0.134843171,0.126701786,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,ascorbic acid,DB00126
,627,DB00316,10039117,119,65355,95,36858,0.012552542,0.706470482,0.534780675,0.935403491,0.042685417,DB0031610039117_,3.153897936,-0.347473858,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,629,DB00404,10039117,38,19854,21,9841,0.679896693,0.896931065,0.512900125,1.60958395,0.806402301,DB0040410039117_,0.215172529,-0.108776271,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,631,DB00497,10039117,40,19227,63,16312,0.002068082,0.538676353,0.352879804,0.813735528,0.009998077,DB0049710039117_,4.60536251,-0.618640347,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,634,DB00996,10039117,54,38899,65,22360,7.79868149156006e-05,0.477541422,0.326448809,0.696110074,0.000644415,DB0099610039117_,7.347167964,-0.739104375,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,636,DB01234,10039117,65,31560,100,32788,0.015413214,0.675298483,0.486199004,0.932413509,0.050361904,DB0123410039117_,2.988520255,-0.392600489,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,637,DB08910,10039117,39,16705,63,17425,0.036781179,0.64574024,0.421400955,0.978476141,0.099137949,DB0891010039117_,2.311242976,-0.437357961,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pomalidomide,DB08910
,639,DB00316,10050819,114,65360,73,36880,0.402553287,0.881177436,0.650951737,1.199251555,0.572354256,DB0031610050819_,0.55799715,-0.12649627,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,643,DB00497,10050819,40,19227,29,16346,0.547118607,1.172626808,0.708672874,1.962175755,0.701769553,DB0049710050819_,0.3541502,0.159246368,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,646,DB00996,10050819,58,38895,28,22397,0.501901941,1.192760774,0.747178352,1.945859543,0.6632893,DB0099610050819_,0.410544035,0.176270598,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,648,DB01234,10050819,88,31537,60,32828,0.013274399,1.526686305,1.086806947,2.157275473,0.044607206,DB0123410050819_,3.10985986,0.423099573,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,651,DB00758,10017788,9,8291,119,9955,1.80791005467891e-21,0.090800092,0.040530733,0.178439465,2.19320790551296e-19,DB0075810017788_,42.9637515,-2.399094983,male,10017788,Gastric haemorrhage,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,653,DB00758,10022972,13,8287,39,10035,0.003208913,0.403673332,0.197570802,0.773121403,0.014289922,DB0075810022972_,4.24820073,-0.907149312,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,clopidogrel,DB00758
,654,DB00065,10000087,33,9431,17,4940,1,1.016796078,0.549701628,1.948410909,1,DB0006510000087_,0,0.016656584,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,infliximab,DB00065
,655,DB00338,10000087,587,33087,254,22018,6.50058482878783e-09,1.537875685,1.323749185,1.790659686,1.52288656171736e-07,DB0033810000087_,15.69748806,0.430402039,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,661,DB00338,10041466,90,33584,35,22237,0.007733122,1.702603811,1.139966165,2.594189092,0.029000585,DB0033810041466_,3.54043928,0.532158733,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,675,DB01164,10008479,78,6446,115,7821,0.190753032,0.822952641,0.608072045,1.10885042,0.337502925,DB0116410008479_,1.086181103,-0.194856624,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,676,DB01164,10013968,161,6363,217,7719,0.320342365,0.900076817,0.727416043,1.111837863,0.488523966,DB0116410013968_,0.716366749,-0.105275167,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium chloride,DB01164
,678,DB01164,10012735,93,6431,78,7858,0.016364791,1.456818782,1.064565259,1.998096371,0.052736902,DB0116410012735_,2.942439833,0.376255142,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,calcium chloride,DB01164
,680,DB00374,10007559,315,17401,104,5620,0.863339481,0.978226303,0.779658944,1.235678753,0.936909221,DB0037410007559_,0.065168884,-0.022014242,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,treprostinil,DB00374
,682,DB00213,10008190,167,18728,144,13277,0.093494377,0.822181783,0.653216971,1.035950341,0.20089124,DB0021310008190_,1.604991614,-0.195793761,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,683,DB00264,10008190,362,29245,314,24578,0.697730479,0.968878386,0.829845372,1.13171457,0.818249967,DB0026410008190_,0.200587406,-0.031616179,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,684,DB00295,10008190,77,14586,53,9549,0.78783577,0.951142619,0.661065248,1.377521889,0.885095921,DB0029510008190_,0.122059255,-0.05009126,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,morphine,DB00295
,685,DB00338,10008190,283,33391,212,22060,0.181043834,0.881919248,0.734837188,1.059690866,0.325161405,DB0033810008190_,1.123433588,-0.125654783,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,686,DB00374,10008190,80,17636,42,5682,0.01457189,0.613694433,0.416779284,0.915241203,0.048166768,DB0037410008190_,3.033085959,-0.488258142,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,689,DB00682,10008190,251,19208,227,16137,0.432245691,0.928954103,0.772230514,1.117969867,0.600680852,DB0068210008190_,0.509691513,-0.073695946,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,690,DB00695,10008190,305,27744,236,20292,0.540127813,0.945262936,0.79408867,1.126233538,0.695721888,DB0069510008190_,0.362805284,-0.056292151,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,691,DB00761,10008190,166,15141,93,8532,1,1.005822496,0.774555465,1.312772501,1,DB0076110008190_,0,0.00580561,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,692,DB00787,10008190,112,16888,132,17116,0.248007706,0.85994452,0.661841746,1.115680056,0.407388498,DB0078710008190_,0.897988008,-0.150887403,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,694,DB01104,10008190,120,15343,51,7235,0.565555629,1.109522098,0.79218275,1.573439994,0.717141672,DB0110410008190_,0.332481868,0.10392938,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,695,DB01202,10008190,79,6635,85,5633,0.134653262,0.789073317,0.572158906,1.087082945,0.262136054,DB0120210008190_,1.33889162,-0.236896038,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,696,DB01234,10008190,232,31393,231,32657,0.641205544,1.044781989,0.866407879,1.259841495,0.777959881,DB0123410008190_,0.251080323,0.043808241,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,697,DB01373,10008190,127,22593,74,7307,9.95760509032342e-05,0.555078222,0.412964343,0.75064709,0.000794101,DB0137310008190_,7.138300053,-0.588646234,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,calcium,DB01373
,698,DB08910,10008190,124,16620,136,17352,0.70900978,0.951908748,0.739485404,1.224477539,0.826334951,DB0891010008190_,0.190755078,-0.049286101,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,699,DB00204,10016256,63,901,40,1003,0.006284944,1.752795355,1.148146156,2.702880598,0.02457964,DB0020410016256_,3.705836808,0.561211859,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dofetilide,DB00204
,700,DB00213,10016256,1300,17595,742,12679,7.62462522605904e-07,1.262501121,1.149379521,1.3875248,1.12813551402737e-05,DB0021310016256_,11.39235918,0.23309477,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,701,DB00264,10016256,1930,27677,1419,23473,7.56072120952217e-05,1.153514733,1.074155,1.238941043,0.000627217,DB0026410016256_,7.374218737,0.142813571,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,702,DB00295,10016256,566,14097,356,9246,0.55952296,1.042785031,0.909247783,1.197145321,0.712223589,DB0029510016256_,0.339363387,0.041895048,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,703,DB00338,10016256,2392,31282,1432,20840,0.001951087,1.112839985,1.039388453,1.19171228,0.009543931,DB0033810016256_,4.651849856,0.106915293,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,704,DB00567,10016256,265,4254,107,1974,0.250853608,1.149207877,0.908630799,1.461686247,0.410693683,DB0056710016256_,0.889907638,0.139072902,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,705,DB00620,10016256,307,4521,146,2986,0.001502681,1.388747055,1.130262529,1.712425805,0.007705419,DB0062010016256_,4.865831431,0.328401942,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,706,DB00682,10016256,1399,18060,902,15462,9.46488957016784e-11,1.327867488,1.217008815,1.44940753,3.09241295651786e-09,DB0068210016256_,19.59431416,0.283574263,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,707,DB00695,10016256,2080,25969,1228,19300,4.9220858093153e-10,1.258822934,1.169606423,1.355192537,1.44636138063558e-08,DB0069510016256_,18.05162973,0.230177105,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,708,DB00761,10016256,1138,14169,550,8075,0.002092782,1.179138879,1.060145931,1.312704833,0.010099842,DB0076110016256_,4.59523554,0.164784408,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,709,DB00787,10016256,1219,15781,1125,16123,0.018552397,1.107034184,1.016983111,1.20510094,0.058233789,DB0078710016256_,2.843289527,0.101684533,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,710,DB00878,10016256,68,1118,42,878,0.238045887,1.271344232,0.843541915,1.935158643,0.3955518,DB0087810016256_,0.927473527,0.240074791,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,chlorhexidine,DB00878
,711,DB01104,10016256,993,14470,419,6867,0.051931922,1.124700545,0.998638664,1.268341152,0.128679352,DB0110410016256_,2.050431613,0.117516818,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,712,DB01202,10016256,341,6373,220,5498,0.00097741,1.337154434,1.120908024,1.59768565,0.00540811,DB0120210016256_,5.219855669,0.2905438,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,713,DB01373,10016256,1639,21081,536,6845,0.89707014,0.992879337,0.89658719,1.100807535,0.956338178,DB0137310016256_,0.044643686,-0.007146136,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,714,DB00811,10018884,116,2682,149,4007,0.250279341,1.163110369,0.899896638,1.500401777,0.410034436,DB0081110018884_,0.891514134,0.151097769,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ribavirin,DB00811
,715,DB00864,10018884,38,6831,48,8344,0.913769733,0.967010584,0.613973139,1.513419266,0.961391243,DB0086410018884_,0.039373832,-0.033545838,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,tacrolimus,DB00864
,716,DB01015,10018884,89,9798,88,9293,0.82085427,0.959225371,0.7053106,1.304771703,0.904598656,DB0101510018884_,0.100263907,-0.041629225,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,717,DB08934,10018884,39,4450,47,6157,0.583613589,1.148072015,0.729834246,1.796945085,0.731569611,DB0893410018884_,0.312562901,0.138084027,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,sofosbuvir,DB08934
,719,DB00497,10012735,867,18400,595,15780,4.07879447846221e-05,1.24964904,1.122044512,1.392468724,0.000370921,DB0049710012735_,7.899522324,0.222862744,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,720,DB00497,10019211,646,18621,314,16061,3.77157755268539e-17,1.774451579,1.545588958,2.040547419,2.95487081884756e-15,DB0049710019211_,33.45532146,0.573491405,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,721,DB00497,10028836,78,19189,42,16333,0.016905183,1.580710394,1.07212568,2.359791119,0.05416954,DB0049710028836_,2.915636522,0.457874362,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,722,DB00497,10037660,423,18844,380,15995,0.430977442,0.944892146,0.819346922,1.089952636,0.599393743,DB0049710037660_,0.511836562,-0.05668449,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,729,DB00996,10000381,73,38880,41,22384,0.922833622,1.02506328,0.689672442,1.542141319,0.96624768,DB0099610000381_,0.03433508,0.024754347,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,730,DB00327,10013573,161,5977,102,4160,0.485221499,1.09860425,0.849118502,1.426673077,0.649308748,DB0032710013573_,0.431846946,0.094040511,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,731,DB00996,10013573,1364,37589,666,21759,0.000365952,1.185582897,1.07818297,1.304539582,0.002380657,DB0099610013573_,6.040378724,0.170234549,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,734,DB00327,10024855,61,6077,30,4232,0.133939755,1.415958965,0.898624902,2.275340779,0.261230723,DB0032710024855_,1.342351266,0.347807015,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,735,DB00996,10024855,289,38664,151,22274,0.345456085,1.102597217,0.901829105,1.352394219,0.514873735,DB0099610024855_,0.663833582,0.097668503,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,738,DB00327,10045555,64,6074,55,4207,0.260911132,0.805986363,0.551996588,1.180168335,0.422397702,DB0032710045555_,0.861807986,-0.215688455,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,739,DB00996,10045555,120,38833,64,22361,0.646214845,1.079678318,0.790279606,1.486852581,0.781673134,DB0099610045555_,0.246318613,0.076663143,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,740,DB01255,10033295,31,2102,28,1550,0.507211596,0.816449216,0.471664972,1.419063874,0.667838341,DB0125510033295_,0.403709139,-0.202790565,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lisdexamfetamine,DB01255
,741,DB00254,10013710,60,5875,47,3341,0.106230615,0.726024732,0.486080198,1.089928803,0.220548007,DB0025410013710_,1.511639888,-0.320171199,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,742,DB00537,10013710,105,7452,135,4163,2.47434355179786e-10,0.43452722,0.332477119,0.566615111,7.60235187130413e-09,DB0053710013710_,18.69480818,-0.83349669,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,743,DB01611,10013710,71,11842,35,2326,3.09984214338553e-05,0.398490543,0.261549678,0.617197403,0.000292093,DB0161110013710_,8.13843821,-0.920071512,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,753,DB00537,10028813,446,7111,172,4126,6.09779691840177e-06,1.504494484,1.253499591,1.812153684,7.03293514700265e-05,DB0053710028813_,9.562321329,0.408456951,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ciprofloxacin,DB00537
,754,DB01611,10028813,659,11254,90,2271,0.000477923,1.477540572,1.177995316,1.871450885,0.002976475,DB0161110028813_,5.817015491,0.39037893,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,755,DB00537,10047700,289,7268,80,4218,1.0621018924693e-09,2.096401777,1.626193569,2.728326393,2.93712238227833e-08,DB0053710047700_,17.34325042,0.740222435,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ciprofloxacin,DB00537
,756,DB01611,10047700,318,11595,34,2327,0.000262296,1.876956513,1.311264044,2.76610904,0.001807193,DB0161110047700_,6.315980384,0.629651589,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,759,DB01611,10060795,79,11834,24,2337,0.081907782,0.650068304,0.406244287,1.076092013,0.181560639,DB0161110060795_,1.706165583,-0.430677839,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,hydroxychloroquine,DB01611
,763,DB00005,10066797,179,127903,27,42392,4.79272840201935e-05,2.197453987,1.460412485,3.427320114,0.000426101,DB0000510066797_,7.760833314,0.787299411,NA,10066797,Injection site recall reaction,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,764,DB00813,10021097,231,10341,265,9903,0.050549569,0.834785461,0.695197213,1.001896876,0.126006019,DB0081310021097_,2.071425607,-0.18058052,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,fentanyl,DB00813
,765,DB00635,10012174,334,32719,286,23508,0.033229495,0.839072396,0.713697628,0.986966326,0.091771711,DB0063510012174_,2.388451184,-0.175458288,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,768,DB00635,10047700,905,32148,506,23288,3.33190132164116e-06,1.295609252,1.159201026,1.449269076,4.14897790522731e-05,DB0063510047700_,10.09006345,0.258981049,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,771,DB01101,10047700,413,7176,166,3742,0.005246512,1.29735116,1.076026338,1.569789359,0.021261883,DB0110110047700_,3.850839341,0.260324617,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,774,DB00512,10013968,152,4585,172,4926,0.651590828,0.949435337,0.755379235,1.192497131,0.785978498,DB0051210013968_,0.240825843,-0.051887853,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vancomycin,DB00512
,775,DB09153,10013968,403,7396,284,5415,0.662794904,1.038937217,0.886642756,1.21858698,0.794417715,DB0915310013968_,0.230145866,0.038198284,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,776,DB00512,10020751,49,4688,28,5070,0.008060753,1.89246152,1.163892485,3.132715358,0.029972684,DB0051210020751_,3.507468859,0.637878373,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,vancomycin,DB00512
,777,DB09153,10020751,68,7731,31,5668,0.031544898,1.608147129,1.035512787,2.548581387,0.088119202,DB0915310020751_,2.429064809,0.475082665,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,sodium chloride,DB09153
,778,DB00480,10070863,691,66737,936,66726,1.48831468321466e-09,0.738130626,0.667663037,0.815720644,3.98983696566011e-08,DB0048010070863_,17.03693037,-0.303634471,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,779,DB01234,10070863,558,31067,780,32108,6.76676913903778e-08,0.739361814,0.661277373,0.826238829,1.27046090585434e-06,DB0123410070863_,13.57613081,-0.301967878,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,780,DB01229,10011906,901,4840,488,2221,0.007524448,0.847270947,0.749502635,0.958479949,0.02836771,DB0122910011906_,3.56250377,-0.165734746,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,789,DB00412,10000891,42,1022,85,1301,0.01668636,0.629124981,0.420011126,0.930117978,0.053599042,DB0041210000891_,2.92622408,-0.463425343,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,790,DB00412,10007559,514,550,590,796,0.004728657,1.260711406,1.070170091,1.485352722,0.019556724,DB0041210007559_,3.934436101,0.23167617,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,793,DB00480,10062355,1107,66321,1211,66451,0.038044489,0.915928839,0.842851906,0.995233596,0.101708645,DB0048010062355_,2.285642974,-0.087816604,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,794,DB00005,10012735,1869,126213,486,41933,1.08291745153545e-06,1.277674529,1.154976175,1.415551307,1.53488731267778e-05,DB0000510012735_,11.0844685,0.245041652,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,795,DB00222,10012735,232,2974,158,2970,0.000303437,1.466282621,1.184836125,1.818242462,0.002035912,DB0022210012735_,6.196811581,0.382730369,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,glimepiride,DB00222
,796,DB00331,10012735,1778,23168,1097,19655,5.46258712657521e-16,1.375008984,1.271545237,1.487389547,3.7636724147321e-14,DB0033110012735_,30.91079612,0.318460265,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,797,DB00338,10012735,2333,31341,1246,21026,2.28619299816565e-10,1.256141428,1.169499468,1.349640117,7.06140810302985e-09,DB0033810012735_,18.76862136,0.228044664,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,798,DB00451,10012735,3049,44222,857,14562,6.05086015028769e-05,1.171537076,1.083136819,1.268125534,0.000519591,DB0045110012735_,7.562468255,0.158316627,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,799,DB00641,10012735,857,13267,589,11886,1.37651614333025e-06,1.303536665,1.168869543,1.454396337,1.90882230690771e-05,DB0064110012735_,10.86643901,0.265081082,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,800,DB00678,10012735,1019,14580,605,10119,0.003212961,1.168933912,1.052619856,1.298943788,0.014304316,DB0067810012735_,4.24719395,0.156092147,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,801,DB00695,10012735,1975,26074,1007,19521,1.36421717912836e-22,1.468344156,1.357226498,1.589300225,1.80193208811e-20,DB0069510012735_,45.46284239,0.384135342,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,802,DB00863,10012735,706,9967,288,5552,1.15688786746129e-05,1.365492443,1.184120246,1.577754931,0.000123287,DB0086310012735_,9.000993646,0.311515127,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,803,DB00996,10012735,1950,37003,910,21515,6.92315161596763e-08,1.245908558,1.148979764,1.351792652,1.29750474314231e-06,DB0099610012735_,13.55506757,0.219865029,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,804,DB01203,10012735,46,653,27,478,0.394473579,1.246896048,0.746768494,2.11805357,0.56439615,DB0120310012735_,0.57199888,0.220657301,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,nadolol,DB01203
,805,DB00374,10065154,82,17634,36,5688,0.132337717,0.734727616,0.490205311,1.1208998,0.259088261,DB0037410065154_,1.350586501,-0.308255439,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,treprostinil,DB00374
,807,DB00820,10053377,65,11850,14,5802,0.003699687,2.273147344,1.261287005,4.39010456,0.016020803,DB0082010053377_,4.13386723,0.821165366,NA,10053377,Central venous catheterisation,10042613,Surgical and medical procedures,Surg,tadalafil,DB00820
,808,DB01240,10053377,148,5603,35,1541,0.46679916,1.162964446,0.796145902,1.740385899,0.633395242,DB0124010053377_,0.456660657,0.150972302,NA,10053377,Central venous catheterisation,10042613,Surgical and medical procedures,Surg,epoprostenol,DB01240
,809,DB06403,10053377,78,21393,23,6638,0.906932985,1.052247619,0.653191216,1.757547872,0.95853111,DB0640310053377_,0.04235326,0.050928466,NA,10053377,Central venous catheterisation,10042613,Surgical and medical procedures,Surg,ambrisentan,DB06403
,810,DB00820,10064687,251,11664,66,5750,2.24021272660364e-06,1.874719672,1.421477571,2.502236798,2.92833572837492e-05,DB0082010064687_,10.43849121,0.62845914,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,tadalafil,DB00820
,811,DB01240,10064687,415,5336,105,1471,0.471943374,1.089558163,0.870302224,1.373618249,0.638049507,DB0124010064687_,0.449339402,0.085772259,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,812,DB06403,10064687,225,21246,70,6591,1,0.997145764,0.758181533,1.325293199,1,DB0640310064687_,0,-0.002858317,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,820,DB08827,10070592,35,1127,27,555,0.099217133,0.638529704,0.371267285,1.108941247,0.209648486,DB0882710070592_,1.562323027,-0.448587082,NA,10070592,Product used for unknown indication,10042613,Surgical and medical procedures,Surg,lomitapide,DB08827
,821,DB00820,10000087,296,11619,93,5723,0.000126699,1.567666063,1.234962413,2.005414436,0.000976764,DB0082010000087_,6.931265709,0.449587929,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,822,DB01240,10000087,237,5514,49,1527,0.066695768,1.339381541,0.975501459,1.87098122,0.155388962,DB0124010000087_,1.861823875,0.292207971,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,823,DB06403,10000087,409,21062,84,6577,0.000334694,1.520391885,1.197467706,1.949649885,0.002209576,DB0640310000087_,6.114954687,0.418968121,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,824,DB00820,10021789,190,11725,53,5763,0.000189802,1.761979928,1.290978076,2.440738278,0.001379107,DB0082010021789_,6.586318994,0.566438136,NA,10021789,Infection,10021881,Infections and infestations,Infec,tadalafil,DB00820
,825,DB01240,10021789,145,5606,41,1535,0.85663629,0.96836779,0.676971514,1.411952939,0.931153356,DB0124010021789_,0.071331293,-0.032143315,NA,10021789,Infection,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,826,DB06403,10021789,165,21306,59,6602,0.344199401,0.866601736,0.639143671,1.188936292,0.513524875,DB0640310021789_,0.666456808,-0.143175766,NA,10021789,Infection,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,833,DB01050,10037377,130,17978,54,9317,0.185015836,1.24757297,0.900775531,1.748758874,0.330163363,DB0105010037377_,1.108167707,0.22120004,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,841,DB00682,10025082,122,19337,52,16312,2.38657397098125e-05,1.979060764,1.418329741,2.79547207,0.000232069,DB0068210025082_,8.368477145,0.68262237,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,842,DB00820,10025082,122,11793,40,5776,0.028619418,1.493803866,1.035812378,2.195081038,0.081652167,DB0082010025082_,2.505286924,0.401325797,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,843,DB01240,10025082,74,5677,15,1561,0.362832988,1.356453039,0.769048839,2.55221168,0.532350828,DB0124010025082_,0.630452555,0.304873233,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,844,DB08932,10025082,243,19200,89,6508,0.525889005,0.925465973,0.721796478,1.195563935,0.683832616,DB0893210025082_,0.380042105,-0.077457914,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,845,DB00682,10025127,66,19393,34,16330,0.020528178,1.634553979,1.064404889,2.5516366,0.063090694,DB0068210025127_,2.763182001,0.491369972,NA,10025127,Lung transplant,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,846,DB00820,10025127,76,11839,40,5776,0.692422185,0.926975829,0.623196801,1.397426706,0.81469638,DB0082010025127_,0.204939775,-0.075827788,NA,10025127,Lung transplant,10042613,Surgical and medical procedures,Surg,tadalafil,DB00820
,847,DB01240,10025127,143,5608,44,1532,0.47231536,0.887835826,0.625961264,1.281020089,0.638342763,DB0124010025127_,0.448879893,-0.118968433,NA,10025127,Lung transplant,10042613,Surgical and medical procedures,Surg,epoprostenol,DB01240
,848,DB08932,10025127,176,19267,75,6522,0.108297141,0.794361668,0.60198472,1.056874176,0.223516184,DB0893210025127_,1.498271458,-0.23021642,NA,10025127,Lung transplant,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,850,DB00820,10057925,49,11866,22,5794,0.801035011,1.087538566,0.644563559,1.890777233,0.892358774,DB0082010057925_,0.113887015,0.083916947,NA,10057925,Transplant evaluation,10022891,Investigations,Inv,tadalafil,DB00820
,851,DB01240,10057925,81,5670,19,1557,0.624367753,1.170650891,0.701037694,2.050458297,0.764203597,DB0124010057925_,0.268921037,0.157559911,NA,10057925,Transplant evaluation,10022891,Investigations,Inv,epoprostenol,DB01240
,852,DB08932,10057925,75,19368,34,6563,0.184648418,0.747489755,0.4916544,1.157539743,0.329731559,DB0893210057925_,1.109476414,-0.291034679,NA,10057925,Transplant evaluation,10022891,Investigations,Inv,macitentan,DB08932
,859,DB00203,10025482,1014,12864,335,8603,2.65609398463873e-30,2.024191092,1.781677516,2.304159417,6.0974175009807e-28,DB0020310025482_,62.66451728,0.70517016,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,860,DB00559,10025482,529,9130,112,3194,7.82041224664787e-07,1.65232858,1.339457662,2.052737239,1.15353274917587e-05,DB0055910025482_,11.37009628,0.502185554,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,861,DB00203,10028813,1521,12357,397,8541,1.39352285296254e-72,2.647940305,2.361162985,2.975099188,1.70366270651722e-69,DB0020310028813_,158.3455909,0.973782094,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,862,DB00559,10028813,592,9067,103,3203,3.04515993490751e-12,2.030288653,1.637580615,2.53778029,1.26249256922782e-10,DB0055910028813_,22.79276293,0.708177976,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,863,DB00203,10042772,462,13416,195,8743,2.99588443253613e-07,1.543961591,1.30023073,1.838873583,4.8820100625674e-06,DB0020310042772_,12.22995352,0.434351575,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,864,DB00559,10042772,313,9346,82,3224,0.029913608,1.316690703,1.025772461,1.706085899,0.084527971,DB0055910042772_,2.470672782,0.275121546,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,bosentan,DB00559
,865,DB00203,10047700,874,13004,242,8696,4.39903321334095e-37,2.415011724,2.086595185,2.803250569,1.52142878964035e-34,DB0020310047700_,77.86824328,0.881704142,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,868,DB00540,10010264,52,2431,20,1071,0.698608554,1.145405388,0.668315603,2.036086072,0.8188048,DB0054010010264_,0.199909563,0.135758625,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,nortriptyline,DB00540
,869,DB01104,10010264,302,15161,138,7148,0.796527658,1.031741811,0.839073546,1.273842178,0.889807667,DB0110410010264_,0.116749944,0.031248453,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,871,DB00540,10013573,77,2406,29,1062,0.521485287,1.171921933,0.7503971,1.875321305,0.680312093,DB0054010013573_,0.385203626,0.158645079,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,nortriptyline,DB00540
,872,DB01104,10013573,526,14937,203,7083,0.01383474,1.228651869,1.040341208,1.455559635,0.046112875,DB0110410013573_,3.076663078,0.205917527,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,875,DB01104,10013710,189,15274,162,7124,3.40522502847357e-08,0.544137516,0.437923919,0.676766992,6.80397870569577e-07,DB0110410013710_,14.20058811,-0.608553277,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,878,DB01104,10019063,144,15319,122,7164,2.31959473090847e-06,0.551971565,0.429947617,0.709629085,3.0153584323407e-05,DB0110410019063_,10.40920676,-0.594258746,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,881,DB01104,10042772,103,15360,48,7238,1,1.011171724,0.710337551,1.457338158,1,DB0110410042772_,0,0.011109781,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,884,DB01104,10061024,56,15407,21,7265,0.394815737,1.257391816,0.748754867,2.188010099,0.564682319,DB0110410061024_,0.571491974,0.229039588,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,sertraline,DB01104
,886,DB00186,10013700,382,16519,131,9877,2.03827854965215e-08,1.743510575,1.423671968,2.146248509,4.26052896044587e-07,DB0018610013700_,14.66870233,0.555900652,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,lorazepam,DB00186
,887,DB00230,10013700,1553,18121,412,8239,7.57640379078702e-23,1.713795283,1.531520749,1.921009295,1.0186484585209e-20,DB0023010013700_,46.03322515,0.538710375,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,pregabalin,DB00230
,888,DB00338,10013700,571,33103,181,22091,5.36979341491516e-20,2.105223131,1.776400708,2.504506842,5.54597327744774e-18,DB0033810013700_,39.73345955,0.744421462,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,omeprazole,DB00338
,889,DB00343,10013700,254,8482,71,5024,4.56521655066441e-09,2.118872427,1.618707805,2.803919359,1.10698078444847e-07,DB0034310013700_,16.01645936,0.750884073,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,diltiazem,DB00343
,890,DB00571,10013700,186,4937,37,2572,9.020701753085e-09,2.618621666,1.825536664,3.847523956,2.04940651231721e-07,DB0057110013700_,15.40054541,0.962648098,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,propranolol,DB00571
,891,DB00924,10013700,476,9686,89,4162,1.41917859238655e-14,2.298018728,1.823393039,2.923924778,8.18050642563168e-13,DB0092410013700_,27.83185215,0.832047329,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,cyclobenzaprine,DB00924
,892,DB00950,10013700,124,4594,21,2035,9.73851272878573e-06,2.615326785,1.63246301,4.387404692,0.000106187,DB0095010013700_,9.150304413,0.961389055,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,fexofenadine,DB00950
,893,DB00186,10013968,738,16163,332,9676,1.73453424006007e-05,1.330718055,1.164529633,1.523154805,0.000176155,DB0018610013968_,8.644147161,0.285718688,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,894,DB00230,10013968,570,19104,217,8434,0.070944419,1.159628089,0.98789912,1.365113951,0.162966953,DB0023010013968_,1.814207844,0.148099341,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,895,DB00338,10013968,1636,32038,930,21342,0.000157316,1.171814866,1.078520119,1.273833447,0.001175229,DB0033810013968_,6.746292203,0.158553714,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,896,DB00343,10013968,851,7885,348,4747,2.97807655198196e-09,1.472162895,1.291167565,1.681200591,7.52542486700559e-08,DB0034310013968_,16.40239347,0.386732677,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,897,DB00571,10013968,141,4982,51,2558,0.036643949,1.419473189,1.019675145,2.003064782,0.098874526,DB0057110013968_,2.313903643,0.350285809,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,propranolol,DB00571
,898,DB00924,10013968,389,9773,142,4109,0.159993533,1.15176154,0.94455819,1.410783982,0.297455793,DB0092410013968_,1.212489659,0.141292544,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,899,DB00950,10013968,230,4488,87,1969,0.26056458,1.159813781,0.896972985,1.510780748,0.422018608,DB0095010013968_,0.86270587,0.148259458,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fexofenadine,DB00950
,900,DB00175,10012735,520,7611,322,5784,0.005096188,1.22723453,1.061335965,1.420709416,0.020770913,DB0017510012735_,3.874201688,0.204763288,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,901,DB00193,10012735,1061,18259,384,8318,0.000146075,1.258658604,1.115666719,1.422391186,0.001101584,DB0019310012735_,6.811005811,0.230046554,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,902,DB00268,10012735,133,2842,42,1503,0.003380871,1.674525173,1.168254108,2.443081963,0.014897936,DB0026810012735_,4.206532593,0.515529646,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ropinirole,DB00268
,903,DB00404,10012735,1046,18846,347,9515,9.71362092352994e-12,1.521899604,1.343075935,1.727700082,3.71919192971572e-10,DB0040410012735_,21.71234451,0.419959294,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,904,DB01067,10012735,278,4083,235,4588,0.001952732,1.329244275,1.10745926,1.596535885,0.009549316,DB0106710012735_,4.6512858,0.284610567,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,glipizide,DB01067
,905,DB01104,10012735,801,14662,299,6987,0.000389536,1.276641303,1.11290888,1.467424149,0.002508623,DB0110410012735_,5.988021439,0.244232647,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,906,DB05676,10012735,8785,38344,4690,20639,0.688806853,1.008231364,0.969210498,1.048857946,0.81240636,DB0567610012735_,0.207754621,0.008197671,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,907,DB00175,10013573,275,7856,195,5911,0.538318173,1.061111474,0.877160876,1.285487179,0.694259025,DB0017510013573_,0.364910153,0.05931692,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,908,DB00193,10013573,592,18728,235,8467,0.100932879,1.138904638,0.975305678,1.333334951,0.212199218,DB0019310013573_,1.550229738,0.130066956,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,909,DB00268,10013573,117,2858,71,1474,0.307352896,0.849930398,0.623030957,1.166154459,0.474477432,DB0026810013573_,0.745541223,-0.162600817,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ropinirole,DB00268
,910,DB00331,10013573,806,24140,615,20137,0.104394916,1.093278745,0.981412723,1.218273831,0.217587157,DB0033110013573_,1.525155788,0.089181204,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,metformin,DB00331
,911,DB00404,10013573,668,19224,203,9659,1.38681383797255e-10,1.653339316,1.408091361,1.947971665,4.41579669668184e-09,DB0040410013573_,19.23807757,0.502797071,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,912,DB01067,10013573,143,4218,147,4676,0.550357192,1.078390184,0.847279576,1.37232792,0.704616791,DB0106710013573_,0.350101182,0.075469358,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,glipizide,DB01067
,913,DB05676,10013573,702,46427,370,24959,0.771600817,1.019980938,0.897144888,1.161076763,0.875014307,DB0567610013573_,0.133515042,0.019783939,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,914,DB00175,10016256,555,7576,393,5713,0.359393201,1.064950187,0.929815165,1.22050825,0.529120357,DB0017510016256_,0.636539354,0.062928025,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,915,DB00193,10016256,1207,18113,492,8210,0.054806717,1.111965745,0.997126793,1.241413291,0.133996331,DB0019310016256_,2.009942857,0.10612939,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,916,DB00268,10016256,203,2772,107,1438,0.901351764,0.98418391,0.767906088,1.266945,0.956927891,DB0026810016256_,0.044027239,-0.015942499,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,917,DB00331,10016256,1414,23532,1021,19731,0.000406202,1.161214063,1.0682432,1.262593465,0.002596352,DB0033110016256_,5.953647871,0.149466064,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,918,DB00451,10016256,3650,43621,1127,14292,0.096826319,1.061123116,0.989592778,1.138428122,0.20601261,DB0045110016256_,1.579817896,0.059327891,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,919,DB01067,10016256,226,4135,256,4567,0.814824486,0.975042195,0.807581466,1.176652445,0.900608932,DB0106710016256_,0.104684153,-0.025274532,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,920,DB05676,10016256,1156,45973,639,24690,0.564388751,0.971550927,0.88021043,1.073168022,0.716214856,DB0567610016256_,0.333775079,-0.028861591,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,921,DB00175,10019211,360,7771,149,5957,1.34944140313469e-10,1.852017662,1.521161064,2.263838558,4.30461981570331e-09,DB0017510019211_,19.26357702,0.616275673,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,922,DB00193,10019211,994,18326,208,8494,2.02506360824436e-28,2.214913964,1.901175766,2.59023873,4.03248461687143e-26,DB0019310019211_,58.4728297,0.79521356,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,923,DB00268,10019211,171,2804,38,1507,2.00798801442702e-07,2.418102252,1.682524128,3.553742376,3.40515902962672e-06,DB0026810019211_,12.59021891,0.882983039,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ropinirole,DB00268
,924,DB00331,10019211,1035,23911,446,20306,2.46747657682497e-34,1.970718494,1.759057906,2.210444825,7.246661656072e-32,DB0033110019211_,71.70218207,0.678398194,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,metformin,DB00331
,925,DB00404,10019211,1073,18819,246,9616,5.91055804197024e-33,2.228701224,1.934181545,2.576024778,1.58529610339988e-30,DB0040410019211_,68.61678158,0.801419005,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,926,DB00451,10019211,2638,44633,436,14983,8.10273768501002e-48,2.031095428,1.831434556,2.256782304,4.48379915895765e-45,DB0045110019211_,102.1158585,0.708575267,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,927,DB01067,10019211,179,4182,88,4735,8.88439875374183e-11,2.302873601,1.768031537,3.017771219,2.90817461073604e-09,DB0106710019211_,19.65574023,0.834157735,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,glipizide,DB01067
,928,DB01104,10019211,765,14698,188,7098,5.68186473783258e-18,1.9650325,1.668740701,2.323276712,4.90469013576122e-16,DB0110410019211_,35.25116957,0.675508785,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,929,DB05676,10019211,6485,40644,2680,22649,2.19585944682889e-35,1.348421749,1.285165856,1.415055578,6.87121018570205e-33,DB0567610019211_,74.05796782,0.298934834,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,930,DB00175,10028813,480,7651,246,5860,4.30674017486367e-07,1.494420402,1.27393305,1.756542989,6.75836808933085e-06,DB0017510028813_,11.9047291,0.40173844,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,931,DB00193,10028813,1250,18070,360,8342,1.72301035422837e-15,1.602923307,1.420255977,1.81251568,1.12940965488511e-13,DB0019310028813_,29.81191114,0.471829029,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,932,DB00268,10028813,230,2745,69,1476,2.17214454669221e-05,1.792136932,1.352854099,2.398857268,0.00021432,DB0026810028813_,8.448040833,0.583408724,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ropinirole,DB00268
,933,DB00331,10028813,1717,23229,884,19868,4.18420645336024e-34,1.661250809,1.52746179,1.807707947,1.20321022610238e-31,DB0033110028813_,71.19514471,0.507570818,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,934,DB01067,10028813,247,4114,164,4659,1.72006045183321e-07,1.705497879,1.387840105,2.100267665,2.96567982790659e-06,DB0106710028813_,12.72840427,0.533857079,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,glipizide,DB01067
,935,DB01104,10028813,933,14530,294,6992,2.30673079914439e-10,1.527082618,1.333737961,1.752404801,7.11648110980168e-09,DB0110410028813_,18.76085246,0.42335913,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,936,DB05676,10028813,8764,38365,3087,22242,9.46962029029366e-114,1.64588953,1.574434442,1.720891911,2.07424141108641e-110,DB0567610028813_,252.5547647,0.498280986,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,937,DB00175,10046571,196,7935,83,6023,5.62299766018606e-06,1.792356029,1.376503524,2.351087137,6.5485375940625e-05,DB0017510046571_,9.633683708,0.583530972,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,pravastatin,DB00175
,938,DB00193,10046571,420,18900,90,8612,4.78512314158195e-12,2.126370418,1.687172255,2.70460579,1.93801173769617e-10,DB0019310046571_,22.36418836,0.754416497,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,tramadol,DB00193
,939,DB00268,10046571,97,2878,28,1517,0.005323624,1.825813096,1.182275964,2.902224237,0.021503107,DB0026810046571_,3.839557859,0.60202542,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ropinirole,DB00268
,940,DB00331,10046571,562,24384,210,20542,1.17351644427998e-25,2.254420737,1.918466506,2.657501528,1.88659814910698e-23,DB0033110046571_,52.32468185,0.812893061,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,metformin,DB00331
,941,DB00404,10046571,376,19516,73,9789,6.26144323372594e-16,2.583450107,2.00331874,3.370580257,4.26378330047892e-14,DB0040410046571_,30.78603444,0.949125756,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,alprazolam,DB00404
,942,DB00451,10046571,1124,46147,162,15257,3.63867500268374e-27,2.294003483,1.941817702,2.724397391,6.57337267666956e-25,DB0045110046571_,55.68160028,0.830298537,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,943,DB01067,10046571,116,4245,64,4759,5.05462533668184e-06,2.031790872,1.480341659,2.810101766,5.98202732889159e-05,DB0106710046571_,9.724165936,0.708917607,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,glipizide,DB01067
,944,DB01104,10046571,293,15170,96,7190,0.001467655,1.44654885,1.142933267,1.844372497,0.007554552,DB0110410046571_,4.885604968,0.369180616,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,sertraline,DB01104
,945,DB05676,10046571,328,46801,60,25269,9.85491864466476e-18,2.951543459,2.234631632,3.955895682,8.23645585294159e-16,DB0567610046571_,34.73279135,1.08232824,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,apremilast,DB05676
,946,DB00175,10047895,156,7975,158,5948,0.007930604,0.73641489,0.584892874,0.927126615,0.029582903,DB0017510047895_,3.520558672,-0.305961609,NA,10047895,Weight decreased,10022891,Investigations,Inv,pravastatin,DB00175
,947,DB00193,10047895,330,18990,157,8545,0.586889074,0.94580729,0.77839909,1.153233376,0.734012767,DB0019310047895_,0.309228856,-0.055716441,NA,10047895,Weight decreased,10022891,Investigations,Inv,tramadol,DB00193
,948,DB00268,10047895,72,2903,25,1520,0.083599447,1.507829455,0.940347003,2.491873967,0.184435985,DB0026810047895_,1.690452842,0.41067117,NA,10047895,Weight decreased,10022891,Investigations,Inv,ropinirole,DB00268
,949,DB00331,10047895,592,24354,568,20184,0.014305087,0.86379862,0.76738175,0.972399973,0.047413051,DB0033110047895_,3.04885775,-0.146415616,NA,10047895,Weight decreased,10022891,Investigations,Inv,metformin,DB00331
,950,DB00404,10047895,423,19469,197,9665,0.490382199,1.065935614,0.896367569,1.271087398,0.653631932,DB0040410047895_,0.425210881,0.063852925,NA,10047895,Weight decreased,10022891,Investigations,Inv,alprazolam,DB00404
,951,DB00451,10047895,1064,46207,392,15027,0.039095543,0.882730602,0.784243484,0.99512204,0.103832105,DB0045110047895_,2.264980059,-0.124735219,NA,10047895,Weight decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,952,DB01067,10047895,103,4258,122,4701,0.63634268,0.932081511,0.707590318,1.225920483,0.773934265,DB0106710047895_,0.256268337,-0.07033501,NA,10047895,Weight decreased,10022891,Investigations,Inv,glipizide,DB01067
,953,DB01104,10047895,269,15194,145,7141,0.201950714,0.871922402,0.708398417,1.076714714,0.351361474,DB0110410047895_,1.045939745,-0.137054847,NA,10047895,Weight decreased,10022891,Investigations,Inv,sertraline,DB01104
,954,DB05676,10047895,1469,45660,879,24450,0.010712172,0.894907542,0.821371396,0.975424131,0.037607778,DB0567610047895_,3.280544398,-0.111034871,NA,10047895,Weight decreased,10022891,Investigations,Inv,apremilast,DB05676
,964,DB06228,10037394,38,15874,38,16038,1,1.010331872,0.626862009,1.628384655,1,DB0622810037394_,0,0.010278863,NA,10037394,Pulmonary haemorrhage,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,965,DB00182,10012174,52,5142,10,2842,0.001187301,2.873742636,1.441944366,6.35217686,0.006350875,DB0018210012174_,5.059162623,1.055615234,female,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,amphetamine,DB00182
,967,DB09072,10012174,72,6399,21,2514,0.248372623,1.346918245,0.816747208,2.311724942,0.407723857,DB0907210012174_,0.897165155,0.297819201,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,sodium oxybate,DB09072
,968,DB00182,10013573,176,5018,50,2802,1.48630287079216e-05,1.965382432,1.422892179,2.757224716,0.000153748,DB0018210013573_,8.780192993,0.675686848,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,969,DB00422,10013573,113,3322,58,2891,0.001063285,1.695362889,1.219466348,2.378323426,0.005793135,DB0042210013573_,5.15108171,0.527896811,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,methylphenidate,DB00422
,970,DB09072,10013573,352,6119,83,2452,9.03996318528256e-06,1.699345807,1.327755661,2.195573032,9.94622990059238e-05,DB0907210013573_,9.21573189,0.530243358,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,973,DB09072,10014928,67,6404,20,2515,0.337868847,1.315556415,0.786520046,2.29426549,0.506972036,DB0907210014928_,0.679299434,0.274259705,NA,10014928,Enuresis,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,974,DB00182,10016173,134,5060,45,2807,0.003373352,1.651805937,1.166260241,2.377609971,0.014866049,DB0018210016173_,4.208675274,0.501869197,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,amphetamine,DB00182
,975,DB00422,10016173,118,3317,59,2890,0.00054684,1.742386127,1.258813036,2.43391968,0.003323011,DB0042210016173_,5.706883891,0.555255511,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,methylphenidate,DB00422
,976,DB09072,10016173,232,6239,74,2461,0.120928168,1.236621145,0.943789904,1.636040648,0.242798525,DB0907210016173_,1.415523296,0.212382777,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium oxybate,DB09072
,985,DB09072,10050584,50,6421,7,2528,0.007145692,2.811751374,1.266562907,7.361572894,0.02723476,DB0907210050584_,3.603261186,1.033807554,female,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium oxybate,DB09072
,999,DB00374,10021789,203,17513,66,5658,0.943206798,0.993698374,0.747949504,1.334783357,0.982141215,DB0037410021789_,0.018020177,-0.006321565,NA,10021789,Infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,1001,DB00374,10040047,324,17392,110,5614,0.651992444,0.950767547,0.761867643,1.193924443,0.786255656,DB0037410040047_,0.240473278,-0.050485676,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,treprostinil,DB00374
,1003,DB00374,10058080,91,17625,24,5700,0.446115615,1.226225086,0.77412884,2.013210661,0.613982718,DB0037410058080_,0.487788497,0.203940414,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,1005,DB00480,10035226,2266,65162,2774,64888,7.55707918499289e-13,0.813439002,0.76836526,0.861073652,3.44259664432475e-11,DB0048010035226_,24.09221,-0.206484338,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,1006,DB00820,10042772,435,11480,140,5676,7.49545659250599e-06,1.536214686,1.263410643,1.877138502,8.42858081428963e-05,DB0082010042772_,9.381297057,0.429321395,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,1007,DB06403,10042772,513,20958,157,6504,0.926712274,1.014026836,0.844477177,1.223034511,0.968977151,DB0640310042772_,0.031514247,0.01392937,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,1008,DB00047,10011906,225,9060,430,8088,1.0064147291928e-20,0.467134829,0.39466277,0.551768433,1.14270458560833e-18,DB0004710011906_,41.31313378,-0.761137349,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,1013,DB00294,10069327,2082,12289,11,157,0.002597988,2.41798337,1.311903008,4.951609791,0.01202044,DB0029410069327_,4.421146784,0.882933875,NA,10069327,Product quality issue,10077536,Product issues,Prod,etonogestrel,DB00294
,1017,DB00169,10003988,1044,37647,354,17821,4.53225712118353e-08,1.396045796,1.234624757,1.581429001,8.82774201039711e-07,DB0016910003988_,13.94019639,0.333643809,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,1018,DB00852,10003988,40,1126,10,461,0.204192368,1.637213141,0.796158569,3.70318692,0.354086411,DB0085210003988_,1.038214296,0.492995492,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pseudoephedrine,DB00852
,1020,DB01065,10003988,79,4252,40,3011,0.091342229,1.39850864,0.941432972,2.106385685,0.197430308,DB0106510003988_,1.622369627,0.335406412,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,melatonin,DB01065
,1021,DB08908,10003988,115,10558,41,3238,0.394318011,0.860255588,0.595994606,1.263499645,0.564231412,DB0890810003988_,0.572290807,-0.150525739,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,dimethyl fumarate,DB08908
,1022,DB00012,10002034,117,1529,92,1221,0.942510201,1.015557378,0.75797481,1.363934277,0.981590848,DB0001210002034_,0.018580709,0.015437603,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,darbepoetin alfa,DB00012
,1023,DB00016,10002034,165,2597,149,2141,0.447047386,0.912957396,0.721555244,1.155893459,0.614814417,DB0001610002034_,0.486434818,-0.091066063,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,erythropoietin,DB00016
,1030,DB00012,10013709,49,1597,45,1268,0.527212367,0.864610142,0.560911104,1.335418902,0.684879755,DB0001210013709_,0.378511996,-0.145476577,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,darbepoetin alfa,DB00012
,1031,DB00016,10013709,85,2677,89,2201,0.121543193,0.785279082,0.573194197,1.075278694,0.243642542,DB0001610013709_,1.412053121,-0.241716105,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,1032,DB00012,10016256,226,1420,136,1177,0.005634319,1.377241292,1.092508213,1.740925636,0.022517574,DB0001210016256_,3.793459192,0.320082434,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,darbepoetin alfa,DB00012
,1033,DB00016,10016256,242,2520,163,2127,0.032919052,1.253068688,1.014285531,1.55112575,0.091105874,DB0001610016256_,2.395732999,0.225595493,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,1037,DB00016,10020772,64,2698,35,2255,0.052263362,1.528199427,0.992684067,2.387394837,0.129275158,DB0001610020772_,2.045812137,0.424090197,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,erythropoietin,DB00016
,1043,DB00016,10038435,46,2716,51,2239,0.150815563,0.74360296,0.486067546,1.134803824,0.285060013,DB0001610038435_,1.255055551,-0.296248043,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,erythropoietin,DB00016
,1044,DB00012,10043554,38,1608,22,1291,0.239840306,1.386607643,0.794882603,2.474590415,0.397678754,DB0001210043554_,0.922110751,0.32686022,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,darbepoetin alfa,DB00012
,1045,DB00016,10043554,43,2719,42,2248,0.444666902,0.846489838,0.538121599,1.332389938,0.612726771,DB0001610043554_,0.489836167,-0.166657082,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,erythropoietin,DB00016
,1052,DB00381,10003598,26,29334,30,22857,0.17728096,0.675319755,0.383514756,1.181769379,0.320351302,DB0038110003598_,1.138337067,-0.392568989,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,1054,DB00695,10003598,53,27996,33,20495,0.512862597,1.175724818,0.746985421,1.875349488,0.672986539,DB0069510003598_,0.39602995,0.161884824,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,1057,DB00012,10011906,350,1296,253,1060,0.183204144,1.131436212,0.940589863,1.36223165,0.32792107,DB0001210011906_,1.114982339,0.12348781,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,darbepoetin alfa,DB00012
,1058,DB00196,10011906,171,4912,203,3082,1.99827952486719e-09,0.528564519,0.426533792,0.654429592,5.22894746750961e-08,DB0019610011906_,16.76647074,-0.637590402,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,1059,DB00285,10011906,309,10642,202,3516,8.07396763396266e-13,0.50540322,0.420137607,0.609069,3.6685261756043e-11,DB0028510011906_,24.02864603,-0.682398713,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,1060,DB00381,10011906,1223,28137,1255,21632,2.56245560766964e-12,0.749218619,0.690513292,0.812861608,1.07939335973712e-10,DB0038110011906_,22.94945175,-0.288724457,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,1061,DB00425,10011906,500,12195,416,7068,1.41923808065959e-07,0.696650718,0.60838468,0.797958027,2.49446158142009e-06,DB0042510011906_,12.90143765,-0.361471116,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,1062,DB00695,10011906,1668,26381,1747,18781,2.18897509296591e-27,0.679740696,0.633585176,0.729198712,4.03769896972695e-25,DB0069510011906_,56.16895236,-0.386043883,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,1063,DB00829,10011906,374,7678,338,4116,2.40376538005700e-11,0.593174153,0.508149065,0.692671403,8.64196540016539e-10,DB0082910011906_,20.8692209,-0.522267242,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,1064,DB09140,10011906,262,3479,138,1660,0.375255434,0.905910455,0.728033843,1.130978478,0.545145443,DB0914010011906_,0.606702652,-0.098814813,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,1066,DB00196,10035598,35,5048,33,3252,0.134258546,0.683309515,0.41148609,1.136937958,0.261658328,DB0019610035598_,1.340715716,-0.380807352,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluconazole,DB00196
,1068,DB00374,10035598,177,17539,52,5672,0.588815776,1.100776838,0.802599563,1.532318569,0.735599937,DB0037410035598_,0.307068872,0.096016147,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,1069,DB00381,10035598,164,29196,178,22709,0.002181314,0.71664877,0.575649518,0.891694898,0.010448444,DB0038110035598_,4.561302245,-0.333169419,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,1070,DB00425,10035598,60,12635,44,7440,0.265181399,0.802984813,0.534568779,1.214442257,0.42714055,DB0042510035598_,0.850642163,-0.219419478,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,1071,DB00695,10035598,344,27705,279,20249,0.205809872,0.901158375,0.766467905,1.060262049,0.35619624,DB0069510035598_,1.032273464,-0.10407426,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,1073,DB09140,10035598,99,3642,41,1757,0.464842205,1.164840691,0.797829101,1.727827404,0.631757386,DB0914010035598_,0.459249842,0.152584332,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,1075,DB00196,10038695,54,5029,64,3221,0.001153887,0.540468959,0.368080805,0.79099308,0.006200005,DB0019610038695_,5.083205118,-0.615318074,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluconazole,DB00196
,1076,DB00285,10038695,62,10889,10,3708,0.028708823,2.111293552,1.07315645,4.623715448,0.081853136,DB0028510038695_,2.502828656,0.747300817,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,venlafaxine,DB00285
,1077,DB00374,10038695,313,17403,156,5568,1.31180413571136e-05,0.641954331,0.526770065,0.784875511,0.00013784,DB0037410038695_,8.88941419,-0.443238114,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,1078,DB00381,10038695,239,29121,205,22682,0.313598524,0.908071922,0.749718802,1.100689964,0.481072526,DB0038110038695_,0.731737238,-0.096431694,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,1079,DB00425,10038695,73,12622,64,7420,0.021009417,0.670570439,0.472130333,0.954352558,0.064272872,DB0042510038695_,2.744617627,-0.399626527,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,1080,DB00695,10038695,415,27634,335,20193,0.180089723,0.905235847,0.781041417,1.049795288,0.323920715,DB0069510038695_,1.127256501,-0.099559765,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,1081,DB00829,10038695,74,7978,34,4420,0.419700234,1.205764296,0.791686691,1.870285572,0.588646319,DB0082910038695_,0.529929753,0.187113636,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diazepam,DB00829
,1082,DB09140,10038695,162,3579,78,1720,1,0.998130336,0.752323448,1.333406081,1,DB0914010038695_,0,-0.001871414,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,1083,DB00108,10046571,446,9748,138,3157,0.693670882,1.046649759,0.859033338,1.281663182,0.815581461,DB0010810046571_,0.203853972,0.045594357,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,natalizumab,DB00108
,1085,DB08868,10016256,1081,8121,245,2266,0.004991201,1.231112916,1.062135526,1.431076355,0.020442789,DB0886810016256_,3.890125058,0.20791857,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,1086,DB08868,10017577,303,8899,115,2396,0.002878349,0.709421769,0.567678949,0.891426024,0.013068037,DB0886810017577_,4.337585926,-0.343305051,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,1088,DB08868,10025482,270,8932,50,2461,0.010430114,1.48777278,1.092833711,2.061226213,0.036804343,DB0886810025482_,3.302139429,0.397280223,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,1090,DB08868,10037660,215,8987,71,2440,0.165595267,0.822169145,0.623419774,1.095117323,0.30493706,DB0886810037660_,1.187649883,-0.195809133,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,1091,DB08868,10040984,40,9162,13,2498,0.614342853,0.83891698,0.438730433,1.712320114,0.755840897,DB0886810040984_,0.279924379,-0.175643528,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,fingolimod,DB08868
,1092,DB08868,10044565,157,9045,43,2468,1,0.996249013,0.70465628,1.43491503,1,DB0886810044565_,0,-0.00375804,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,1094,DB08868,10048393,647,8555,173,2338,0.825533612,1.022080255,0.85730243,1.223424774,0.907781329,DB0886810048393_,0.096751757,0.021840016,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,1095,DB00335,10013709,423,8043,235,5230,0.059948311,1.170415229,0.991653806,1.384027161,0.143373036,DB0033510013709_,1.942305404,0.157358583,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,1096,DB00590,10013709,29,747,87,1865,0.461795498,0.832281283,0.522310544,1.292593118,0.628981197,DB0059010013709_,0.463653916,-0.183584814,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,doxazosin,DB00590
,1098,DB00335,10042209,47,8419,7,5458,3.35817538331589e-05,4.352481408,1.953105414,11.42208912,0.000313402,DB0033510042209_,8.068024224,1.470746121,female,10042209,Stress,10037175,Psychiatric disorders,Psych,atenolol,DB00335
,1101,DB00335,10047895,192,8274,113,5352,0.441478829,1.099076719,0.864307202,1.402850305,0.609724202,DB0033510047895_,0.494748552,0.094470481,NA,10047895,Weight decreased,10022891,Investigations,Inv,atenolol,DB00335
,1102,DB00590,10047895,13,763,46,1906,0.309089392,0.706020736,0.34789659,1.338357988,0.476449371,DB0059010047895_,0.741393813,-0.348110672,NA,10047895,Weight decreased,10022891,Investigations,Inv,doxazosin,DB00590
,1104,DB00335,10047899,155,8311,61,5404,0.000731935,1.652146802,1.218352394,2.264605915,0.004245126,DB0033510047899_,5.461983893,0.502075535,NA,10047899,Weight increased,10022891,Investigations,Inv,atenolol,DB00335
,1107,DB06605,10055798,331,13742,392,12641,0.000890248,0.776746359,0.667611453,0.903304152,0.005006993,DB0660510055798_,5.296919816,-0.252641418,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,apixaban,DB06605
,1109,DB06643,10058467,45,52376,10,7505,0.218311216,0.644817284,0.320185781,1.435617382,0.371507854,DB0664310058467_,0.990185274,-0.438788283,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,denosumab,DB06643
,1114,DB00363,10035664,87,4541,140,6748,0.584954109,0.923446063,0.696450074,1.218809295,0.732568728,DB0036310035664_,0.311198116,-0.079642886,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,clozapine,DB00363
,1116,DB00363,10047700,45,4583,60,6828,0.617384186,1.117377382,0.74046246,1.675637305,0.758403707,DB0036310047700_,0.27653944,0.110984316,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,clozapine,DB00363
,1120,DB00451,10025409,47,47224,9,15410,0.162726645,1.704023575,0.825382715,3.95600264,0.300993623,DB0045110025409_,1.200666201,0.532992263,NA,10025409,Macular degeneration,10015919,Eye disorders,Eye,levothyroxine,DB00451
,1126,DB00451,10047531,75,47196,20,15399,0.475564893,1.223531709,0.738877335,2.116767544,0.64116317,DB0045110047531_,0.444471299,0.20174152,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,levothyroxine,DB00451
,1127,DB00999,10047531,49,21381,15,12224,0.036661645,1.867593994,1.029498517,3.587404111,0.098901968,DB0099910047531_,2.31362614,0.624650968,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,hydrochlorothiazide,DB00999
,1130,DB00060,10011906,289,9219,158,2307,1.68507406743779e-13,0.457756935,0.373662628,0.562352466,8.38073261354821e-12,DB0006010011906_,25.50508578,-0.781416945,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,1142,DB06196,10019860,391,649,122,161,0.098728414,0.795207839,0.603977774,1.048417755,0.208926525,DB0619610019860_,1.565772644,-0.229151765,NA,10019860,Hereditary angioedema,10010331,"Congenital, familial and genetic disorders",Cong,icatibant,DB06196
,1143,DB06404,10019860,1505,1564,453,447,0.495301004,0.949516789,0.816069467,1.104806692,0.657591013,DB0640410019860_,0.419172102,-0.051802067,NA,10019860,Hereditary angioedema,10010331,"Congenital, familial and genetic disorders",Cong,human c1-esterase inhibitor,DB06404
,1152,DB01255,10051076,47,2086,43,1535,0.331920702,0.804363295,0.51753838,1.2529003,0.500733162,DB0125510051076_,0.691681931,-0.217704253,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lisdexamfetamine,DB01255
,1154,DB06196,10051076,62,978,14,269,0.567556961,1.217905393,0.661547037,2.393576814,0.718708614,DB0619610051076_,0.330299268,0.197132493,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,icatibant,DB06196
,1155,DB06404,10051076,181,2888,41,859,0.137441435,1.312977182,0.922208176,1.907282485,0.266144698,DB0640410051076_,1.323715141,0.272297217,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,human c1-esterase inhibitor,DB06404
,1156,DB08896,10016256,210,613,239,801,0.209954159,1.148047674,0.922106713,1.428797908,0.361085161,DB0889610016256_,1.018641445,0.138062825,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,regorafenib,DB08896
,1157,DB00295,10019211,390,14273,148,9454,4.34810224318162e-09,1.745391503,1.438133818,2.127422785,1.05872966616053e-07,DB0029510019211_,16.06102589,0.556978888,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,morphine,DB00295
,1158,DB08896,10019211,73,750,54,986,0.002161956,1.77664157,1.215963095,2.609233318,0.01037368,DB0889610019211_,4.568483422,0.574724824,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,regorafenib,DB08896
,1160,DB08896,10033553,73,750,82,958,0.448451336,1.137057311,0.805727887,1.602255236,0.616164939,DB0889610033553_,0.484240593,0.128443619,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,regorafenib,DB08896
,1161,DB00295,10048294,127,14536,135,9467,9.93699980508977e-05,0.612717851,0.476363406,0.787710674,0.000792818,DB0029510048294_,7.139916297,-0.489850724,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,morphine,DB00295
,1163,DB00203,10021097,675,13203,336,8602,7.5279175307964e-05,1.30883861,1.143271938,1.500599771,0.00062489,DB0020310021097_,7.37793546,0.269140187,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sildenafil,DB00203
,1164,DB00722,10021097,428,24975,669,25363,3.59271642369226e-12,0.649708911,0.573410852,0.735563256,1.47208965232659e-10,DB0072210021097_,22.63916801,-0.431230846,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,lisinopril,DB00722
,1186,DB06643,10027452,69,52352,36,7479,7.38352699417001e-09,0.273800019,0.180325532,0.422192069,1.7076639422944e-07,DB0664310027452_,15.58296933,-1.295357296,male,10027452,Metastases to bone,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,denosumab,DB06643
,1190,DB06643,10003658,96,52325,19,7496,0.203384862,0.723838828,0.438961369,1.25517237,0.353114111,DB0664310003658_,1.040964012,-0.323186525,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,denosumab,DB06643
,1191,DB06643,10007559,80,52341,28,7487,0.000190928,0.408705508,0.262571952,0.653456427,0.001385764,DB0664310007559_,6.581503877,-0.894760412,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,denosumab,DB06643
,1194,DB00060,10008190,162,9346,36,2429,0.426321302,1.169521727,0.808325835,1.733286402,0.594980111,DB0006010008190_,0.5192273,0.156594885,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,1195,DB00060,10008531,193,9315,51,2414,0.87319677,0.980712728,0.714403605,1.367453353,0.944720193,DB0006010008531_,0.056866487,-0.019475698,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,1200,DB00060,10044565,173,9335,37,2428,0.302546793,1.21610502,0.845944668,1.789921183,0.468894013,DB0006010044565_,0.75737852,0.195653145,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,1201,DB00060,10046543,57,9451,8,2457,0.122548724,1.852189933,0.877731172,4.501979828,0.245088124,DB0006010046543_,1.406137444,0.616368686,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,interferon beta-1a,DB00060
,1202,DB00060,10050584,130,9378,13,2452,0.000349823,2.614526844,1.473147463,5.05052428,0.002293616,DB0006010050584_,6.077625574,0.961083142,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,interferon beta-1a,DB00060
,1203,DB00060,10051290,140,9368,39,2426,0.709397903,0.929619686,0.64579009,1.365993384,0.826585273,DB0006010051290_,0.190452193,-0.072979717,NA,10051290,Central nervous system lesion,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,1205,DB00060,10020937,287,9221,69,2396,0.595103935,1.080775635,0.824910469,1.432483792,0.740779832,DB0006010020937_,0.30005182,0.077678964,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,1206,DB00060,10033371,392,9116,85,2380,0.133095543,1.204015933,0.94565614,1.547519375,0.260056966,DB0006010033371_,1.346854571,0.18566258,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,1208,DB00005,10011224,2742,125340,717,41702,6.39471277535979e-09,1.272362077,1.170616726,1.384367469,1.50142943546523e-07,DB0000510011224_,15.71167804,0.240875076,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,1209,DB00005,10025482,4242,123840,1004,41415,1.16495537248495e-23,1.412933606,1.317496497,1.516495405,1.64186873811083e-21,DB0000510025482_,47.85845189,0.345668114,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,1210,DB00005,10036790,431,127651,180,42239,0.009882208,0.792307054,0.664044014,0.948477303,0.035225754,DB0000510036790_,3.345977805,-0.232806268,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,1211,DB00005,10039101,914,127168,263,42156,0.045868449,1.152048437,1.002871503,1.327069311,0.117235723,DB0000510039101_,2.143568642,0.141541607,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,1212,DB00005,10052251,550,127532,182,42237,1,1.000841252,0.844575982,1.190529175,1,DB0000510052251_,0,0.000840898,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,1214,DB01255,10016256,131,2002,67,1511,0.011887244,1.475543572,1.082229485,2.027225378,0.040862644,DB0125510016256_,3.197538979,0.389026446,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lisdexamfetamine,DB01255
,1216,DB01255,10027175,35,2098,15,1563,0.083651859,1.738070373,0.921099691,3.43776209,0.184510752,DB0125510027175_,1.690047542,0.552775517,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,lisdexamfetamine,DB01255
,1218,DB01255,10033371,50,2083,23,1555,0.05639223,1.622664277,0.96708731,2.798931308,0.136797541,DB0125510033371_,1.989253251,0.484069414,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,lisdexamfetamine,DB01255
,1231,DB00005,10002198,94,127988,14,42405,0.003530929,2.224418892,1.261944393,4.224998905,0.015425991,DB0000510002198_,4.171701452,0.799495709,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,etanercept,DB00005
,1232,DB01060,10002198,56,8531,34,5047,0.913152321,0.974398367,0.624260995,1.54132436,0.961104948,DB0106010002198_,0.039671669,-0.025935058,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,amoxicillin,DB01060
,1233,DB00005,10025169,36,128046,21,42398,0.045407455,0.567629783,0.322481862,1.023461237,0.116357296,DB0000510025169_,2.151089682,-0.566285864,NA,10025169,Lyme disease,10021881,Infections and infestations,Infec,etanercept,DB00005
,1235,DB00005,10034839,344,127738,64,42355,9.15027216964456e-06,1.782138503,1.36112404,2.365865815,0.000100534,DB0000510034839_,9.205015348,0.577814049,NA,10034839,Pharyngitis streptococcal,10021881,Infections and infestations,Infec,etanercept,DB00005
,1237,DB00005,10005911,78,128004,14,42405,0.030054267,1.845598369,1.036815635,3.531595401,0.084825562,DB0000510005911_,2.46715834,0.612803544,NA,10005911,Body temperature increased,10022891,Investigations,Inv,etanercept,DB00005
,1242,DB00005,10008469,373,127709,99,42320,0.048672082,1.248517024,0.997534324,1.5749118,0.122568593,DB0000510008469_,2.099084462,0.221956466,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,1243,DB00126,10008469,70,10101,29,5916,0.143073801,1.413692323,0.903714367,2.263828235,0.274143086,DB0012610008469_,1.294105099,0.34620495,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,1244,DB00153,10008469,50,7373,21,3418,0.798303332,1.1037571,0.649776552,1.937966551,0.891009846,DB0015310008469_,0.115399801,0.098719905,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,1245,DB00193,10008469,108,19212,29,8673,0.012203276,1.681184102,1.106075303,2.630203172,0.041709004,DB0019310008469_,3.177038245,0.519498368,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,1246,DB00586,10008469,49,7060,13,2792,0.257151661,1.490613262,0.794789768,2.999802022,0.418016748,DB0058610008469_,0.872233781,0.39918762,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,1247,DB00126,10011224,239,9932,118,5827,0.13439827,1.18832316,0.946809726,1.497944326,0.261814164,DB0012610011224_,1.340120323,0.172543204,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,1248,DB00153,10011224,184,7239,68,3371,0.115007765,1.259990501,0.946045256,1.694860459,0.233624104,DB0015310011224_,1.454041848,0.231104182,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,1249,DB00193,10011224,319,19001,88,8614,2.39762307557871e-05,1.643347568,1.292151239,2.108317192,0.000232896,DB0019310011224_,8.364920699,0.496735361,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,1250,DB00586,10011224,127,6982,36,2769,0.079669633,1.398987387,0.956775926,2.091807448,0.177874485,DB0058610011224_,1.726677117,0.33574868,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diclofenac,DB00586
,1251,DB00126,10022000,127,10044,65,5880,0.408297775,1.143844558,0.840203014,1.569897775,0.577693824,DB0012610022000_,0.548711266,0.134395008,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,1252,DB00153,10022000,93,7330,51,3388,0.322783451,0.842881212,0.591184928,1.213527887,0.491149556,DB0015310022000_,0.711006603,-0.170929242,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ergocalciferol,DB00153
,1253,DB00193,10022000,183,19137,67,8635,0.149829872,1.23240541,0.925604017,1.657838173,0.283686525,DB0019310022000_,1.259885437,0.208967878,NA,10022000,Influenza,10021881,Infections and infestations,Infec,tramadol,DB00193
,1254,DB00586,10022000,84,7025,30,2775,0.6770459,1.106036987,0.719276207,1.742997923,0.804145929,DB0058610022000_,0.217974522,0.100783345,NA,10022000,Influenza,10021881,Infections and infestations,Infec,diclofenac,DB00586
,1255,DB00126,10022061,93,10078,11,5934,2.05948382000276e-09,4.977351992,2.654437997,10.32662234,5.37039010007664e-08,DB0012610022061_,16.73978019,1.604898021,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,1256,DB00153,10022061,122,7301,12,3427,4.67140419968163e-10,4.772097377,2.630050852,9.504075543,1.37731754782537e-08,DB0015310022061_,18.10054294,1.56278591,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,1257,DB00193,10022061,152,19168,19,8683,1.13399077866793e-09,3.623489127,2.240475177,6.189660561,3.11636706810356e-08,DB0019310022061_,17.28401282,1.287437409,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,1258,DB00586,10022061,81,7028,6,2799,9.45653553518251e-07,5.376169234,2.361664697,15.10003903,1.3634944407146e-05,DB0058610022061_,11.20287462,1.681976082,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,1259,DB00126,10022095,76,10095,13,5932,4.31115880920917e-06,3.435086374,1.89149286,6.751385852,5.18265764006691e-05,DB0012610022095_,9.867607482,1.234042071,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,1260,DB00153,10022095,81,7342,11,3428,1.41366447615129e-05,3.437641239,1.820038408,7.168183696,0.000147307,DB0015310022095_,8.822992252,1.23478555,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,1261,DB00193,10022095,79,19241,20,8682,0.021750663,1.78230193,1.07952845,3.076596277,0.066052356,DB0019310022095_,2.717307576,0.577905748,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,1263,DB00126,10022437,240,9931,110,5835,0.033284453,1.281918047,1.016253678,1.625334803,0.091875311,DB0012610022437_,2.387322935,0.248357431,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ascorbic acid,DB00126
,1264,DB00153,10022437,134,7289,63,3376,0.938431922,0.985142921,0.722789679,1.354959492,0.978144719,DB0015310022437_,0.022097646,-0.01496855,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ergocalciferol,DB00153
,1265,DB00193,10022437,375,18945,141,8561,0.068000549,1.201802347,0.985892549,1.471631612,0.157708953,DB0019310022437_,1.847004015,0.183822386,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,1266,DB00586,10022437,150,6959,55,2750,0.695394101,1.077732208,0.783626412,1.500829474,0.81661725,DB0058610022437_,0.202584776,0.074859026,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,diclofenac,DB00586
,1267,DB00153,10033425,258,7165,47,3392,7.47450089460758e-11,2.598540723,1.892560048,3.636106754,2.49323928952741e-09,DB0015310033425_,19.80968305,0.954950027,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,1268,DB00193,10033425,505,18815,190,8512,0.034181972,1.202418879,1.013611638,1.431146452,0.09377655,DB0019310033425_,2.366840454,0.18433526,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,1269,DB00586,10033425,247,6862,76,2729,0.059337505,1.292453862,0.99155789,1.700888812,0.142255228,DB0058610033425_,1.950132453,0.25654263,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,1270,DB00005,10046306,1148,126934,273,42146,4.14598520085439e-07,1.396204659,1.221946095,1.599846559,6.53732579510843e-06,DB0000510046306_,11.93798238,0.333757598,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,1271,DB00126,10046306,110,10061,40,5905,0.008404899,1.613983954,1.112732812,2.383159475,0.030982788,DB0012610046306_,3.474323451,0.478705628,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,1272,DB00153,10046306,71,7352,28,3411,0.51587033,1.176428754,0.748285859,1.896393534,0.675584257,DB0015310046306_,0.392177396,0.16248337,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,ergocalciferol,DB00153
,1273,DB00193,10046306,151,19169,41,8661,0.003652494,1.664004676,1.170213205,2.413481266,0.015855624,DB0019310046306_,4.144231004,0.509227153,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,tramadol,DB00193
,1274,DB00586,10046306,63,7046,17,2788,0.172199163,1.466373808,0.845644886,2.677996434,0.313729027,DB0058610046306_,1.159225637,0.382792556,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,diclofenac,DB00586
,1276,DB00115,10022086,212,18213,43,10429,1.20178329618974e-11,2.823019344,2.024060303,4.018906951,4.54516171803557e-10,DB0011510022086_,21.51178762,1.037807002,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,1278,DB00126,10022086,114,10057,28,5917,1.04558552663692e-05,2.395293318,1.570610676,3.767800166,0.000112821,DB0012610022086_,9.089707339,0.873505694,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,1279,DB00158,10022086,485,16330,86,8018,9.73241653738006e-22,2.768904227,2.193664415,3.529978637,1.20953460371175e-19,DB0015810022086_,43.55888111,1.018451656,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,1280,DB00169,10022086,426,38265,74,18101,1.45681721244793e-18,2.72315295,2.121736295,3.536817163,1.32499793872643e-16,DB0016910022086_,36.55995058,1.001790382,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,1282,DB00316,10022086,467,65007,120,36833,1.91560385213616e-16,2.2050019,1.799740534,2.718969048,1.38518974562308e-14,DB0031610022086_,31.91035417,0.790728371,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,1283,DB00341,10022086,142,11263,40,5028,0.00959905,1.584741729,1.106911146,2.314575453,0.034464011,DB0034110022086_,3.367839657,0.460421447,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,1284,DB00482,10022086,116,8143,22,3049,0.002657189,1.974200749,1.241089337,3.277944996,0.01224585,DB0048210022086_,4.40256818,0.680163632,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,1285,DB00563,10022086,1447,45199,231,15117,3.69063136868429e-29,2.095100331,1.819822525,2.420631576,7.76065964206932e-27,DB0056310022086_,60.12073017,0.739601443,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,1286,DB00635,10022086,579,32474,116,23678,2.71454319900387e-46,3.639284225,2.97432181,4.484823414,1.37214938434263e-43,DB0063510022086_,98.69478059,1.291787021,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,1287,DB01098,10022086,77,8072,40,7169,0.006758798,1.709589823,1.150508994,2.575095043,0.026062496,DB0109810022086_,3.647257936,0.536253472,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,1288,DB00043,10002198,403,6010,90,2210,1.51277920351146e-05,1.646487009,1.299831968,2.103882225,0.000156119,DB0004310002198_,8.764894735,0.498643933,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,omalizumab,DB00043
,1291,DB00588,10002198,107,16417,25,8443,0.000199781,2.201074454,1.412333078,3.555058309,0.001438892,DB0058810002198_,6.543882146,0.788945629,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,fluticasone propionate,DB00588
,1292,DB00635,10002198,157,32896,56,23738,2.64552615542145e-06,2.023041181,1.481555757,2.797668037,3.38861704090648e-05,DB0063510002198_,10.29250358,0.704601914,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,prednisone,DB00635
,1293,DB00668,10002198,151,9940,52,4251,0.189903041,1.241836661,0.898557183,1.740159808,0.336383951,DB0066810002198_,1.089502061,0.216591462,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,epinephrine,DB00668
,1296,DB00863,10002198,100,10573,48,5792,0.490220523,1.141250693,0.799864974,1.648085922,0.653503053,DB0086310002198_,0.425408074,0.13212476,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,ranitidine,DB00863
,1297,DB00950,10002198,53,4665,15,2041,0.146313704,1.545792909,0.855975547,2.960043129,0.278800402,DB0095010002198_,1.277259159,0.435536988,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,fexofenadine,DB00950
,1299,DB01075,10002198,177,19771,89,11008,0.479780396,1.107303653,0.852608916,1.446702446,0.644617806,DB0107510002198_,0.439097686,0.101927918,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,diphenhydramine,DB01075
,1300,DB01222,10002198,72,9202,18,5387,0.000635852,2.341543068,1.380217033,4.17649926,0.003782329,DB0122210002198_,5.57741526,0.850810143,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,budesonide,DB01222
,1301,DB00169,10008469,276,38415,93,18082,0.005050244,1.39693877,1.099722365,1.787758089,0.020625493,DB0016910008469_,3.881227455,0.33428325,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,1302,DB00338,10008469,285,33389,108,22164,3.52438653000365e-07,1.751704363,1.397972192,2.208166737,5.64696738440389e-06,DB0033810008469_,12.0843919,0.560589235,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,1303,DB00588,10008469,240,16284,83,8385,0.00167336,1.488910585,1.153691135,1.937610135,0.008403625,DB0058810008469_,4.779092157,0.398044702,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,1304,DB00635,10008469,287,32766,88,23706,9.80002061317631e-14,2.35951964,1.850971521,3.033285315,5.02977389969945e-12,DB0063510008469_,26.01564608,0.858458056,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,1306,DB01409,10008469,100,5931,37,3929,0.002035107,1.790308524,1.213605027,2.692299568,0.009862331,DB0140910008469_,4.619032752,0.582387965,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,1308,DB00169,10008479,539,38152,197,17978,0.002176739,1.289225431,1.092040329,1.527120256,0.01043128,DB0016910008479_,4.56294625,0.254041597,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,1309,DB00338,10008479,544,33130,291,21981,0.003104377,1.240298521,1.072627172,1.436452099,0.01391317,DB0033810008479_,4.274919395,0.215352093,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,1310,DB00635,10008479,512,32541,236,23558,6.50456109530123e-09,1.570585551,1.342241852,1.842117961,1.5231393175055e-07,DB0063510008479_,15.69732211,0.451448512,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,1311,DB00715,10008479,72,4771,17,2270,0.008228842,2.014944357,1.172191396,3.656041116,0.030472683,DB0071510008479_,3.49092462,0.70059158,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,1312,DB01409,10008479,135,5896,70,3896,0.112450013,1.274344295,0.945030432,1.731264716,0.229760084,DB0140910008479_,1.470719628,0.242431768,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,1314,DB00169,10074903,155,38536,45,18130,0.003796651,1.620492249,1.155474389,2.312710419,0.016353131,DB0016910074903_,4.113335891,0.482729961,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,1315,DB00338,10074903,140,33534,74,22198,0.123949399,1.252330185,0.937786182,1.684010323,0.247005068,DB0033810074903_,1.398346426,0.225005964,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,1316,DB00588,10074903,79,16445,30,8438,0.187137611,1.351175452,0.876449934,2.133305608,0.332925202,DB0058810074903_,1.099837434,0.300974919,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,1317,DB00635,10074903,138,32915,45,23749,1.24928764346649e-06,2.212629678,1.569380838,3.172154503,1.74482070714753e-05,DB0063510074903_,10.95627366,0.794181708,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,1321,DB00215,10037153,120,10983,43,5233,0.129089938,1.32968645,0.929716667,1.933473716,0.254300308,DB0021510037153_,1.369239394,0.284943163,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,citalopram,DB00215
,1322,DB00321,10037153,81,7366,21,2829,0.119548423,1.481396728,0.905519622,2.526393457,0.240671719,DB0032110037153_,1.424321437,0.392985378,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,amitriptyline,DB00321
,1323,DB00425,10037153,115,12580,52,7432,0.126175741,1.306513756,0.932478765,1.851956979,0.250379689,DB0042510037153_,1.384776756,0.267362335,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,zolpidem,DB00425
,1324,DB00451,10037153,605,46666,132,15287,1.33657600275738e-05,1.501374404,1.240658454,1.828189171,0.000140107,DB0045110037153_,8.87310215,0.406380958,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,1326,DB00005,10043414,1014,127068,531,41888,5.67851096594591e-17,0.629503847,0.565845279,0.700925618,4.33894362615954e-15,DB0000510043414_,33.07114548,-0.462823314,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,1327,DB00215,10043414,36,11067,16,5260,0.882864464,1.069390166,0.577908874,2.066035917,0.951043643,DB0021510043414_,0.050195326,0.067088548,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,1329,DB00425,10043414,37,12658,18,7466,0.577063928,1.212361343,0.672423035,2.263925112,0.726231208,DB0042510043414_,0.319886846,0.192569981,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,1330,DB00451,10043414,136,47135,25,15394,0.007592993,1.776578936,1.153129453,2.842850519,0.028566782,DB0045110043414_,3.555510704,0.574689569,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,1334,DB00203,10030124,629,13249,252,8686,2.47468135303704e-11,1.636353725,1.407990052,1.906217968,8.86802990655469e-10,DB0020310030124_,20.84339827,0.492470428,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,1335,DB00559,10030124,267,9392,82,3224,0.418396367,1.117712385,0.866559937,1.454485711,0.587413124,DB0055910030124_,0.532026918,0.111284083,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,1336,DB00203,10037423,285,13593,100,8838,4.87653948278993e-08,1.852983465,1.46803496,2.35487239,9.45279058297443e-07,DB0020310037423_,13.87178565,0.616797024,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,1337,DB00559,10037423,167,9492,49,3257,0.38643384,1.169429025,0.843570262,1.646873371,0.556585851,DB0055910037423_,0.585933851,0.156515617,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,1340,DB00005,10020751,1609,126473,304,42115,1.11069809096227e-21,1.762372968,1.557375264,1.999971848,1.37710845853506e-19,DB0000510020751_,43.42913079,0.566661178,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,etanercept,DB00005
,1341,DB00115,10013709,742,17683,360,10112,0.012665053,1.178674772,1.035280016,1.343721785,0.042974366,DB0011510013709_,3.147151478,0.164390733,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,1342,DB00121,10013709,177,4046,24,444,0.335720436,0.809357767,0.519738771,1.311548918,0.504901254,DB0012110013709_,0.683392405,-0.211514226,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,1343,DB00169,10013709,1484,37207,598,17577,0.001223776,1.172319582,1.063558964,1.293418642,0.006497101,DB0016910013709_,5.036399182,0.158984335,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,1344,DB00115,10033371,802,17623,279,10193,1.21514689952655e-13,1.662588829,1.445760665,1.916326515,6.14824566969306e-12,DB0011510033371_,25.81485433,0.508375923,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,1345,DB00121,10033371,205,4018,14,454,0.082059709,1.654368916,0.953175255,3.106723176,0.18179934,DB0012110033371_,1.704851725,0.503419616,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,1346,DB00169,10033371,1632,37059,456,17719,1.95701590276217e-25,1.711185045,1.539093319,1.905610924,3.09880500024721e-23,DB0016910033371_,51.82844059,0.53718614,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,1347,DB00115,10061218,46,18379,11,10461,0.008193576,2.380151485,1.213786061,5.098733061,0.030389184,DB0011510061218_,3.493668511,0.867164135,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,1349,DB00169,10061218,100,38591,24,18151,0.001981299,1.959741121,1.244726827,3.201657549,0.009652199,DB0016910061218_,4.640569564,0.672812384,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,1352,DB00722,10031009,64,25339,41,25991,0.018914742,1.601116159,1.06475889,2.431868799,0.059148653,DB0072210031009_,2.827701469,0.470700986,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,1354,DB00722,10047895,533,24870,508,25524,0.246606274,1.076773225,0.950554652,1.219900414,0.405698382,DB0072210047895_,0.902145297,0.073968814,NA,10047895,Weight decreased,10022891,Investigations,Inv,lisinopril,DB00722
,1355,DB08877,10047895,45,3244,74,3155,0.005464607,0.591475735,0.39765821,0.871312803,0.021961193,DB0887710047895_,3.818478342,-0.525134619,NA,10047895,Weight decreased,10022891,Investigations,Inv,ruxolitinib,DB08877
,1356,DB00722,10047899,369,25034,233,25799,3.92912803251504e-09,1.632059091,1.380155261,1.933116438,9.65825065159413e-08,DB0072210047899_,16.1528682,0.489842463,NA,10047899,Weight increased,10022891,Investigations,Inv,lisinopril,DB00722
,1357,DB08877,10047899,171,3118,79,3150,6.67140553295659e-09,2.186530412,1.657029148,2.905855424,1.55597066933242e-07,DB0887710047899_,15.67599608,0.782316001,NA,10047899,Weight increased,10022891,Investigations,Inv,ruxolitinib,DB08877
,1358,DB00722,10050584,195,25208,137,25895,0.000630524,1.462129852,1.168255304,1.834070124,0.003754718,DB0072210050584_,5.584742149,0.379894175,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,1359,DB08877,10050584,125,3164,70,3159,0.000108994,1.782725631,1.314171231,2.434534026,0.000858526,DB0887710050584_,7.060293139,0.578143446,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,ruxolitinib,DB08877
,1360,DB00222,10028813,206,3000,121,3007,3.93575646024549e-06,1.706297372,1.348520613,2.166545305,4.7883063437886e-05,DB0022210028813_,9.946748698,0.534325744,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,glimepiride,DB00222
,1361,DB01268,10028813,336,1807,390,2740,0.000974021,1.306284942,1.112183147,1.533828586,0.005391057,DB0126810028813_,5.223013725,0.267187186,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,1364,DB00331,10040829,96,24850,45,20707,0.001233444,1.77763719,1.234542315,2.593804133,0.006541781,DB0033110040829_,5.029545803,0.575285061,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,1365,DB00999,10040829,119,21311,36,12203,0.000560331,1.892776681,1.293092873,2.831976758,0.003391271,DB0099910040829_,5.686550415,0.638044895,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,1366,DB01268,10040829,52,2091,53,3077,0.070520279,1.443645124,0.961386221,2.16703228,0.162221636,DB0126810040829_,1.818791755,0.367171251,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,sunitinib,DB01268
,1371,DB00715,10071404,35,4808,54,2233,2.98669411444976e-08,0.301078601,0.190365255,0.470721677,6.03422404291406e-07,DB0071510071404_,14.32064838,-1.200383916,male,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,paroxetine,DB00715
,1373,DB00451,10005830,50,47221,8,15411,0.065934463,2.039609182,0.959181745,4.98248755,0.154038517,DB0045110005830_,1.870552598,0.712758212,NA,10005830,Blood thyroid stimulating hormone abnormal,10022891,Investigations,Inv,levothyroxine,DB00451
,1376,DB00005,10024264,170,127912,69,42350,0.155158525,0.815706968,0.613009172,1.0956503,0.291006961,DB0000510024264_,1.234408093,-0.203700097,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,1377,DB00451,10024264,237,47034,86,15333,0.399892901,0.898379357,0.698622107,1.164477063,0.569773683,DB0045110024264_,0.562516045,-0.107162854,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,1378,DB00005,10047895,733,127349,246,42173,0.852987775,0.986751302,0.852529459,1.145233593,0.928147027,DB0000510047895_,0.074565124,-0.013337245,NA,10047895,Weight decreased,10022891,Investigations,Inv,etanercept,DB00005
,1379,DB01080,10013709,180,1879,177,1935,0.698552562,1.047264807,0.837881088,1.309002457,0.818775683,DB0108010013709_,0.199945124,0.04618182,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,vigabatrin,DB01080
,1380,DB00559,10009033,161,9498,53,3253,0.874372714,1.040428574,0.756264688,1.451095952,0.945583789,DB0055910009033_,0.055952776,0.039632719,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,1387,DB00650,10013968,80,2051,71,1943,0.740268805,1.067439727,0.760768113,1.500114476,0.850770212,DB0065010013968_,0.161613208,0.065263003,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,leucovorin,DB00650
,1392,DB00853,10037660,27,1794,30,2236,0.688883425,1.12170619,0.639064069,1.960221755,0.812447693,DB0085310037660_,0.207703745,0.11485091,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,temozolomide,DB00853
,1393,DB00853,10047700,94,1727,109,2157,0.612858177,1.077085706,0.802490399,1.443481759,0.75468941,DB0085310047700_,0.281448992,0.074258974,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,temozolomide,DB00853
,1396,DB01175,10001488,18,10706,38,4854,2.10068857690416e-08,0.214788693,0.115261113,0.38615686,4.3840094675606e-07,DB0117510001488_,14.64013194,-1.53810056,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,1397,DB01224,10001488,51,8057,117,5800,7.07182607445498e-13,0.313815203,0.220864357,0.440432779,3.22993828613465e-11,DB0122410001488_,24.15597299,-1.158950993,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,1398,DB01175,10013573,359,10365,163,4729,1,1.004862702,0.829956316,1.220713791,1,DB0117510013573_,0,0.004850917,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,1399,DB01224,10013573,212,7896,127,5790,0.075118349,1.224044485,0.975088816,1.541584581,0.170031071,DB0122410013573_,1.771774087,0.202160528,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,1400,DB01175,10016256,766,9958,315,4577,0.110264028,1.117708725,0.974333336,1.28445841,0.226425635,DB0117510016256_,1.485338709,0.111280808,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,1401,DB01224,10016256,305,7803,164,5753,0.001213125,1.371130383,1.126798931,1.673214337,0.00645878,DB0122410016256_,5.042314771,0.315635497,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,1402,DB01175,10020765,35,10689,18,4874,0.658980216,0.88664658,0.488135156,1.664763589,0.791741981,DB0117510020765_,0.233519722,-0.12030882,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,1403,DB01224,10020765,27,8081,30,5887,0.138634053,0.655681991,0.374577537,1.142512926,0.267871362,DB0122410020765_,1.317248407,-0.422079377,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,1406,DB01175,10024264,58,10666,37,4855,0.120098836,0.713535583,0.46372382,1.110357281,0.241511582,DB0117510024264_,1.420837847,-0.337522972,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,1407,DB01224,10024264,55,8053,55,5862,0.100005344,0.727954325,0.490909076,1.079431506,0.210788659,DB0122410024264_,1.556899261,-0.317516973,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,1408,DB01175,10027175,141,10583,51,4841,0.159374047,1.264612018,0.910181827,1.781480191,0.296648587,DB0117510027175_,1.215207048,0.23476537,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,1409,DB01224,10027175,86,8022,59,5858,0.736008414,1.064427671,0.754013105,1.511499723,0.847504322,DB0122410027175_,0.16545934,0.062437257,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,1410,DB01175,10027599,110,10614,24,4868,0.000509233,2.10201238,1.340222157,3.423972788,0.003134337,DB0117510027599_,5.765337503,0.742895162,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,1411,DB01224,10027599,46,8062,15,5902,0.005925492,2.24489521,1.229425438,4.333300986,0.023437146,DB0122410027599_,3.753433093,0.808658843,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,1412,DB01175,10040984,48,10676,22,4870,1,0.995265785,0.588496182,1.733340471,1,DB0117510040984_,0,-0.004745457,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,1413,DB01224,10040984,31,8077,39,5878,0.028264006,0.578500294,0.348544951,0.952655636,0.080848776,DB0122410040984_,2.515174838,-0.547316223,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,1414,DB01175,10047899,222,10502,69,4823,0.004902759,1.47753937,1.120382461,1.969413475,0.020146802,DB0117510047899_,3.904709713,0.390378116,NA,10047899,Weight increased,10022891,Investigations,Inv,escitalopram,DB01175
,1415,DB01224,10047899,162,7946,93,5824,0.06365741,1.276724464,0.981006196,1.669687975,0.150059192,DB0122410047899_,1.896725452,0.244297786,NA,10047899,Weight increased,10022891,Investigations,Inv,quetiapine,DB01224
,1416,DB01175,10053762,339,10385,170,4722,0.307851455,0.906723365,0.749453077,1.100255326,0.47502961,DB0117510053762_,0.74437814,-0.097917875,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,1417,DB01224,10053762,232,7876,205,5712,0.04369295,0.820777351,0.675047975,0.998456068,0.112961079,DB0122410053762_,2.180711957,-0.197503399,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,1418,DB01175,10074903,41,10683,27,4865,0.149414576,0.691536257,0.414729778,1.17050077,0.283165372,DB0117510074903_,1.2617242,-0.368839697,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,1419,DB01224,10074903,89,8019,77,5840,0.269774761,0.841781008,0.612216533,1.159572699,0.43235349,DB0122410074903_,0.838511762,-0.172235384,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,1420,DB01240,10013968,1593,4158,425,1151,0.588517947,1.037568141,0.91397496,1.179168286,0.735420107,DB0124010013968_,0.307313368,0.036879649,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,1421,DB06403,10013968,3858,17613,1151,5510,0.205927704,1.048589155,0.974888526,1.12837574,0.356375527,DB0640310013968_,1.031770252,0.047445599,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,1422,DB08931,10013968,1722,4855,554,1892,0.000589124,1.2112703,1.084456367,1.354116085,0.003541886,DB0893110013968_,5.643096058,0.191669643,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,1423,DB08931,10021789,78,6499,25,2421,0.577916928,1.162235457,0.730453189,1.908581988,0.726775705,DB0893110021789_,0.31913737,0.150345269,NA,10021789,Infection,10021881,Infections and infestations,Infec,riociguat,DB08931
,1424,DB01240,10037660,335,5416,98,1478,0.547010213,0.932857199,0.73694029,1.189423047,0.701715523,DB0124010037660_,0.354227194,-0.069503145,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,1425,DB06403,10037660,425,21046,100,6561,0.011074771,1.32489269,1.061216901,1.667345767,0.038600659,DB0640310037660_,3.254485932,0.281331468,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,1426,DB08931,10037660,218,6359,57,2389,0.015758644,1.436726671,1.064496828,1.966265919,0.051245324,DB0893110037660_,2.971130907,0.362367381,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,1428,DB08934,10017885,29,4460,37,6167,0.802750173,1.083756727,0.64181757,1.814026858,0.893313651,DB0893410017885_,0.112817527,0.080433456,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,sofosbuvir,DB08934
,1429,DB01164,10048959,52,6472,83,7853,0.139428489,0.760205505,0.526044177,1.089912947,0.269041098,DB0116410048959_,1.312891129,-0.274166481,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,1430,DB05259,10020751,220,11050,38,2690,0.056526576,1.409343102,0.992402775,2.050227716,0.136997008,DB0525910020751_,1.987796194,0.34312371,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,glatiramer,DB05259
,1431,DB00059,10016288,186,641,232,875,0.434558274,1.094344934,0.874143516,1.368896779,0.603065612,DB0005910016288_,0.505729279,0.090155951,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,pegaspargase,DB00059
,1432,DB00531,10016288,583,6669,747,5769,1.241383734438e-11,0.675158002,0.601376781,0.75777219,4.6714060786976e-10,DB0053110016288_,21.48439082,-0.392808539,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,cyclophosphamide,DB00531
,1433,DB00541,10016288,402,2732,678,3619,0.000360524,0.78545056,0.685758463,0.898828968,0.002351169,DB0054110016288_,6.05284276,-0.241497764,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,vincristine,DB00541
,1434,DB00563,10016288,305,46341,518,14830,3.66467064032553e-120,0.188433817,0.162837917,0.217769337,9.17389216961492e-117,DB0056310016288_,267.1860942,-1.669008437,male,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,methotrexate,DB00563
,1435,DB00694,10016288,97,537,123,648,0.768170766,0.951647391,0.703971982,1.283970794,0.872806717,DB0069410016288_,0.136041149,-0.049560701,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,daunorubicin,DB00694
,1436,DB00987,10016288,384,1720,626,2302,0.006680955,0.821015238,0.710512235,0.947952603,0.025817246,DB0098710016288_,3.656712568,-0.19721361,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,cytarabine,DB00987
,1437,DB01234,10016288,385,31240,473,32415,0.014649901,0.844571017,0.735664311,0.969122026,0.048391157,DB0123410016288_,3.02843818,-0.168926453,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,dexamethasone,DB01234
,1448,DB00285,10003549,234,10717,88,3630,0.400389363,0.900667424,0.699827027,1.167781549,0.570219596,DB0028510003549_,0.561733736,-0.104619209,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,1451,DB01202,10003549,137,6577,121,5597,0.800761763,0.963512863,0.746955011,1.244198956,0.892281272,DB0120210003549_,0.113973868,-0.037169441,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,1468,DB00285,10013968,310,10641,88,3630,0.144062186,1.201698456,0.942447957,1.545341088,0.275635068,DB0028510013968_,1.288677507,0.183735936,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,venlafaxine,DB00285
,1471,DB01202,10013968,155,6559,88,5630,0.002193156,1.511835203,1.153403421,1.991914998,0.010488921,DB0120210013968_,4.557435721,0.413324279,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levetiracetam,DB01202
,1488,DB00285,10040979,40,10911,23,3695,0.057632877,0.588979314,0.343668889,1.032048156,0.139005338,DB0028510040979_,1.973242944,-0.529364216,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,venlafaxine,DB00285
,1498,DB00285,10041349,180,10771,75,3643,0.146070819,0.811730097,0.614991991,1.080354583,0.278515214,DB0028510041349_,1.278282594,-0.208587387,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,1499,DB00313,10041349,43,1196,37,1480,0.111738174,1.437918872,0.898435712,2.311321446,0.228670033,DB0031310041349_,1.475475221,0.363196841,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,valproic acid,DB00313
,1501,DB01202,10041349,137,6577,124,5594,0.660504765,0.939738208,0.729611571,1.211276936,0.792756519,DB0120210041349_,0.232239143,-0.062153945,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,1513,DB00480,10007559,392,67036,490,67172,0.001172536,0.801625984,0.699800929,0.917772248,0.006280843,DB0048010007559_,5.070251086,-0.221113134,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,1514,DB00264,10011906,1349,28258,1477,23415,5.88229792768457e-13,0.756815003,0.701005331,0.817023968,2.71256493033665e-11,DB0026410011906_,24.33054137,-0.278636437,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,1515,DB00316,10011906,3512,61962,2617,34336,3.66665006827966e-28,0.743685729,0.705553928,0.783924819,7.16564290295396e-26,DB0031610011906_,57.89791463,-0.29613674,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,1516,DB00421,10011906,433,8470,400,4852,3.93444342285048e-11,0.620156693,0.537555025,0.715517657,1.37157619853614e-09,DB0042110011906_,20.40730525,-0.477783103,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,1517,DB00451,10011906,1490,45781,934,14485,5.10180362261192e-54,0.504731817,0.463792906,0.549534465,3.62434887082039e-51,DB0045110011906_,116.1441651,-0.683728046,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,1518,DB00480,10011906,3145,64283,4453,63209,5.95909078810649e-53,0.694471758,0.6623898,0.728029497,3.8203585698873e-50,DB0048010011906_,113.7889104,-0.364603784,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,1520,DB00904,10011906,1295,21774,1125,13331,1.67722649561995e-16,0.704788252,0.648257153,0.766257519,1.22460828992696e-14,DB0090410011906_,32.03357027,-0.349857873,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,1521,DB00451,10013709,2408,44863,586,14833,2.32119976707371e-11,1.358587966,1.238383835,1.492355502,8.35218834736927e-10,DB0045110013709_,20.90332735,0.3064459,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,1523,DB01273,10028813,246,1794,66,1209,1.06717254725874e-11,2.511187409,1.886482497,3.380797763,4.06236501154179e-10,DB0127310028813_,21.62408561,0.920755713,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,varenicline,DB01273
,1528,DB00334,10021113,50,2799,23,2789,0.002014859,2.165852918,1.293113432,3.729577632,0.009785768,DB0033410021113_,4.62682623,0.772814241,NA,10021113,Hypothermia,10018065,General disorders and administration site conditions,Genrl,olanzapine,DB00334
,1529,DB00734,10021113,27,4023,35,4867,0.799730331,0.933258735,0.542314964,1.590008146,0.891736807,DB0073410021113_,0.11458425,-0.069072801,NA,10021113,Hypothermia,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,1532,DB00916,10016173,73,5250,38,2393,0.536587767,0.875657472,0.581920921,1.336510938,0.692877258,DB0091610016173_,0.366902412,-0.132780278,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,metronidazole,DB00916
,1534,DB00916,10070863,52,5271,73,2358,3.36729108342974e-10,0.3187155,0.218183142,0.462798994,1.01559662797419e-08,DB0091610070863_,18.40520449,-1.143456423,male,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,metronidazole,DB00916
,1536,DB00451,10060795,191,47080,53,15366,0.332861515,1.176195723,0.862996029,1.627267104,0.501865082,DB0045110060795_,0.689423956,0.162285267,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,levothyroxine,DB00451
,1537,DB00641,10060795,45,14079,45,12430,0.597348545,0.882880175,0.570456725,1.366401797,0.742483875,DB0064110060795_,0.297754126,-0.124565789,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,simvastatin,DB00641
,1540,DB01261,10003239,104,3677,79,3224,0.367939781,1.154246827,0.849769934,1.572928156,0.537666391,DB0126110003239_,0.620517003,0.143448034,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sitagliptin,DB01261
,1541,DB01261,10017577,40,3741,28,3275,0.394178651,1.250579964,0.750646278,2.109969648,0.564108774,DB0126110017577_,0.572508185,0.223607415,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,1555,DB00563,10003239,2301,44345,609,14739,6.52865055258991e-07,1.255787995,1.145741219,1.378029881,9.80883565446275e-06,DB0056310003239_,11.53222698,0.22776326,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,1556,DB00005,10015150,1468,126614,390,42029,8.07790072304635e-05,1.249468019,1.116112235,1.4014275,0.000664874,DB0000510015150_,7.315912497,0.222717876,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,1557,DB00563,10015150,310,46336,67,15281,0.001468934,1.525827548,1.167576392,2.019392455,0.007558173,DB0056310015150_,4.885125825,0.422536918,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,1558,DB00563,10023232,935,45711,250,15098,0.003093341,1.235281633,1.071889158,1.427808002,0.01387043,DB0056310023232_,4.277996023,0.211298987,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,1559,DB00563,10028391,375,46271,108,15240,0.24418298,1.143620426,0.920127037,1.431199691,0.402719977,DB0056310028391_,0.909513805,0.134199043,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,1560,DB00563,10033425,1336,45310,328,15020,8.25975601658416e-07,1.350202887,1.193965971,1.530383507,1.21120048477498e-05,DB0056310033425_,11.32131346,0.300254868,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,1561,DB01075,10022061,144,19804,22,11075,9.63113936065237e-11,3.66029408,2.325204429,6.02672853,3.14477637384779e-09,DB0107510022061_,19.57752305,1.297543494,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,1562,DB01075,10022093,92,19856,9,11088,8.69722010488933e-10,5.708822212,2.877993246,12.88219525,2.44810620070791e-08,DB0107510022093_,17.525366,1.742012735,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,1568,DB00627,10028411,23,1306,38,1561,0.243762146,0.723522129,0.409253072,1.253281636,0.402152079,DB0062710028411_,0.910924955,-0.323624148,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,niacin,DB00627
,1569,DB01039,10028411,55,2918,35,3016,0.025778066,1.624063695,1.04063306,2.565054041,0.075201136,DB0103910028411_,2.587588937,0.484931462,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fenofibrate,DB01039
,1571,DB00175,10005483,48,8083,39,6067,0.745012127,0.923805845,0.591982777,1.449633979,0.854428367,DB0017510005483_,0.15732261,-0.079253354,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,pravastatin,DB00175
,1572,DB00722,10005483,144,25259,213,25819,0.000656489,0.691052688,0.554983193,0.858429318,0.003884259,DB0072210005483_,5.550823103,-0.369539209,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,lisinopril,DB00722
,1574,DB01268,10005483,7,2136,51,3079,2.54477878311488e-06,0.197895937,0.075611218,0.439091967,3.27168062187208e-05,DB0126810005483_,10.32762166,-1.620013958,male,10005483,Blood creatinine increased,10022891,Investigations,Inv,sunitinib,DB01268
,1575,DB13961,10005483,36,9421,29,6385,0.52730036,0.841347712,0.501050436,1.424067354,0.684888569,DB1396110005483_,0.378499127,-0.172750254,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,fish oil,DB13961
,1576,DB00175,10005750,68,8063,40,6066,0.241859403,1.278930689,0.851698482,1.943052993,0.400004681,DB0017510005750_,0.916279029,0.246024329,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,pravastatin,DB00175
,1577,DB00451,10005750,483,46788,144,15275,0.351687054,1.095041294,0.906422306,1.329587912,0.521406565,DB0045110005750_,0.651225186,0.090792074,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,levothyroxine,DB00451
,1578,DB00722,10005750,347,25056,304,25728,0.04849188,1.172055918,1.000876852,1.373087173,0.122247069,DB0072210005750_,2.101711124,0.158759402,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,lisinopril,DB00722
,1580,DB01268,10005750,106,2037,152,2978,0.896675427,1.019523532,0.782764219,1.324024921,0.956301489,DB0126810005750_,0.044682051,0.019335393,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,sunitinib,DB01268
,1581,DB13961,10005750,96,9361,62,6352,0.807143731,1.05067652,0.754296806,1.472639693,0.895803955,DB1396110005750_,0.11003369,0.049434261,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,fish oil,DB13961
,1582,DB00175,10013950,52,8079,36,6070,0.746666249,1.085270587,0.695056825,1.711254015,0.855634762,DB0017510013950_,0.155911674,0.081829345,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,1583,DB00451,10013950,334,46937,123,15296,0.252353648,0.884906728,0.716946636,1.098115663,0.412468714,DB0045110013950_,0.88559492,-0.122273032,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,1584,DB00722,10013950,148,25255,183,25849,0.09790145,0.827769053,0.661500685,1.03447096,0.207728415,DB0072210013950_,1.571523751,-0.189021085,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,1586,DB01268,10013950,21,2122,38,3092,0.505563377,0.805282939,0.447619051,1.411955213,0.666419265,DB0126810013950_,0.405836279,-0.216561586,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,1587,DB13961,10013950,55,9402,27,6387,0.177128834,1.38377904,0.857047908,2.284154353,0.320189568,DB1396110013950_,1.13884206,0.324818191,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,1588,DB00175,10013968,355,7776,247,5859,0.354854055,1.082942696,0.914660378,1.283728093,0.524660382,DB0017510013968_,0.645004117,0.079682055,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,1589,DB00451,10013968,2140,45131,596,14823,0.000432747,1.179303555,1.074338147,1.295962906,0.00273695,DB0045110013968_,5.90091101,0.164924057,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,1590,DB00722,10013968,1055,24348,937,25095,0.001169952,1.160473,1.059834664,1.270792534,0.006272579,DB0072210013968_,5.071567653,0.148827681,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,1592,DB01268,10013968,65,2078,105,3025,0.52679025,0.901158826,0.647587527,1.246262728,0.684513519,DB0126810013968_,0.379046884,-0.10407376,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sunitinib,DB01268
,1593,DB13961,10013968,384,9073,230,6184,0.131222281,1.137900248,0.960665152,1.350256563,0.257545466,DB1396110013968_,1.356559008,0.129184676,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,1594,DB00722,10016256,1595,23808,1286,24746,4.02671954153817e-11,1.289133909,1.194494787,1.391532178,1.40188507482557e-09,DB0072210016256_,20.38544802,0.253970605,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,1596,DB01268,10016256,441,1702,595,2535,0.168787874,1.103903717,0.959411583,1.269607055,0.309234631,DB0126810016256_,1.173654965,0.098852731,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,1597,DB13961,10016256,754,8703,481,5933,0.277240496,1.068650273,0.947265293,1.206350755,0.440784644,DB1396110016256_,0.819198858,0.066396426,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,1598,DB00175,10021097,117,8014,115,5991,0.044595641,0.760590309,0.581604151,0.994814212,0.114763699,DB0017510021097_,2.164880052,-0.273660424,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,pravastatin,DB00175
,1599,DB00451,10021097,699,46572,351,15068,8.5383248300723e-11,0.64432407,0.56519245,0.735576045,2.80537335198063e-09,DB0045110021097_,19.6917292,-0.439553466,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,1601,DB01268,10021097,33,2110,34,3096,0.168521341,1.42401581,0.851931898,2.377855635,0.308967723,DB0126810021097_,1.174518462,0.353480915,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sunitinib,DB01268
,1602,DB13961,10021097,98,9359,115,6299,5.79534836499095e-05,0.573586589,0.432699777,0.759053388,0.000500841,DB1396110021097_,7.599222256,-0.55584637,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,fish oil,DB13961
,1603,DB00175,10043554,42,8089,43,6063,0.154461772,0.732130435,0.466312388,1.148677385,0.290064134,DB0017510043554_,1.237653228,-0.31179659,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,pravastatin,DB00175
,1604,DB00451,10043554,226,47045,121,15298,1.92788203572612e-05,0.607363028,0.484521921,0.764456915,0.000193377,DB0045110043554_,8.55087016,-0.498628598,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,levothyroxine,DB00451
,1605,DB00722,10043554,113,25290,144,25888,0.091123469,0.803282431,0.6218712,1.035529259,0.197053097,DB0072210043554_,1.624282058,-0.219048907,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,lisinopril,DB00722
,1607,DB01268,10043554,46,2097,56,3074,0.36113282,1.204084616,0.793741467,1.818602563,0.531055804,DB0126810043554_,0.632888171,0.185719623,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,sunitinib,DB01268
,1608,DB13961,10043554,38,9419,40,6374,0.063501838,0.642916834,0.400890195,1.029503597,0.149787291,DB1396110043554_,1.898539055,-0.441739903,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,fish oil,DB13961
,1613,DB01268,10050513,26,2117,63,3067,0.029213485,0.597952262,0.36210395,0.961828116,0.082959858,DB0126810050513_,2.489398421,-0.514244357,NA,10050513,Metastatic renal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sunitinib,DB01268
,1615,DB00175,10061428,129,8002,114,5992,0.214267508,0.847353706,0.651971646,1.102470584,0.366608393,DB0017510061428_,1.003461048,-0.165637073,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,pravastatin,DB00175
,1616,DB00451,10061428,867,46404,329,15090,0.019319941,0.856979878,0.752904249,0.977210248,0.060165232,DB0045110061428_,2.81066064,-0.15434084,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,1617,DB00722,10061428,443,24960,430,25602,0.432389628,1.05675413,0.922237673,1.210926781,0.600812189,DB0072210061428_,0.50947289,0.055202069,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,1619,DB01268,10061428,167,1976,255,2875,0.679412279,0.952857295,0.772608169,1.172865499,0.806064173,DB0126810061428_,0.21559192,-0.048290129,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,sunitinib,DB01268
,1620,DB13961,10061428,151,9306,141,6273,0.006670417,0.721917355,0.56868109,0.916869419,0.025783652,DB1396110061428_,3.658014645,-0.325844613,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,fish oil,DB13961
,1621,DB00175,10061818,62,8069,57,6049,0.266335153,0.815435043,0.558909591,1.191550497,0.42847382,DB0017510061818_,0.847525641,-0.204033514,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,1622,DB00451,10061818,399,46872,187,15232,6.06920605274502e-05,0.693390141,0.580807997,0.830215111,0.000520911,DB0045110061818_,7.559930809,-0.366162465,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,1623,DB00722,10061818,210,25193,242,25790,0.219386602,0.888334612,0.734240086,1.074043714,0.372758683,DB0072210061818_,0.98682403,-0.118406792,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,1625,DB13961,10061818,78,9379,63,6351,0.302208987,0.838391704,0.592838275,1.189683906,0.468550046,DB1396110061818_,0.75811236,-0.176269861,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,1629,DB00412,10011078,391,673,663,723,4.24653494191042e-08,0.633690356,0.536243501,0.748347618,8.32054945569254e-07,DB0041210011078_,13.99936736,-0.456194841,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,1631,DB00448,10013700,178,4967,36,3088,1.4927078657599e-11,3.073608496,2.131660202,4.542254138,5.53006712494699e-10,DB0044810013700_,21.31565098,1.122852277,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,lansoprazole,DB00448
,1632,DB00451,10013700,752,46519,136,15283,1.52345519913309e-11,1.816476858,1.510001024,2.199125377,5.64000280411455e-10,DB0045110013700_,21.29596637,0.596898833,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,levothyroxine,DB00451
,1633,DB00451,10022437,952,46319,217,15202,7.57020630167873e-07,1.439813872,1.239703713,1.678304983,1.12039905765555e-05,DB0045110022437_,11.39924054,0.36451385,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,1634,DB00005,10040943,256,127826,81,42338,0.752792483,1.046837608,0.81212913,1.361539532,0.860759979,DB0000510040943_,0.149939583,0.045773818,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,1635,DB00005,10048592,682,127400,208,42211,0.312212156,1.086367688,0.928424769,1.275516074,0.479701682,DB0000510048592_,0.734590864,0.082839736,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,1636,DB00005,10058112,61,128021,20,42399,1,1.010124451,0.600938787,1.767617067,1,DB0000510058112_,0,0.010073542,NA,10058112,Chondrolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,1637,DB00297,10013709,396,1276,109,770,3.83055840587449e-12,2.191659853,1.734444513,2.786123982,1.56588223481199e-10,DB0029710013709_,22.57740154,0.784659181,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,bupivacaine,DB00297
,1640,DB06290,10053762,109,253,196,477,0.774988429,1.048436612,0.784022303,1.398535481,0.877323349,DB0629010053762_,0.130879655,0.047300114,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,simeprevir,DB06290
,1641,DB08934,10053762,124,4365,211,5993,0.063510922,0.806878333,0.638830213,1.01563991,0.149801202,DB0893410053762_,1.898446187,-0.214582386,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sofosbuvir,DB08934
,1642,DB00203,10009033,177,13701,102,8836,0.387982073,1.119139195,0.870852828,1.444410538,0.558020782,DB0020310009033_,0.583359074,0.112559814,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,1643,DB00374,10009033,134,17582,66,5658,0.006206311,0.653377904,0.482258006,0.892616929,0.024313716,DB0037410009033_,3.716714648,-0.425599598,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,1644,DB00682,10009033,168,19291,108,16256,0.029002854,1.310812632,1.022271747,1.686708383,0.082482016,DB0068210009033_,2.495175001,0.270647275,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,1645,DB06403,10009033,110,21361,36,6625,0.7700306,0.947661205,0.644426411,1.423400427,0.874025881,DB0640310009033_,0.134645292,-0.053758219,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,1646,DB00222,10003549,114,3092,105,3023,0.680295106,1.061501339,0.803068392,1.404118591,0.80660187,DB0022210003549_,0.214925079,0.059684264,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,1647,DB00451,10003549,1516,45755,617,14802,3.58260434184462e-06,0.794867107,0.722009453,0.875915561,4.41588535171798e-05,DB0045110003549_,10.02771712,-0.229580339,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,1649,DB00451,10016326,101,47170,20,15399,0.044025532,1.648542067,1.012882839,2.81398373,0.113635892,DB0045110016326_,2.174755874,0.499891302,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,1650,DB00115,10003549,723,17702,461,10011,0.051764818,0.886943619,0.785970745,1.001613212,0.12834999,DB0011510003549_,2.052994449,-0.119973862,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,1651,DB00126,10003549,369,9802,265,5680,0.010368443,0.806912188,0.684799633,0.951757318,0.036641927,DB0012610003549_,3.306562143,-0.21454043,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,1652,DB00169,10003549,1242,37449,650,17525,0.024035381,0.894188868,0.811182128,0.986390964,0.071309893,DB0016910003549_,2.640720208,-0.111838264,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,1653,DB00343,10003549,349,8387,164,4931,0.01970779,1.25110355,1.032682873,1.520771402,0.06109078,DB0034310003549_,2.795394332,0.224026002,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,1654,DB00542,10003549,36,1650,54,1370,0.007052836,0.553648553,0.350467013,0.865494685,0.026953008,DB0054210003549_,3.613660359,-0.591225174,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,benazepril,DB00542
,1655,DB00695,10003549,1103,26946,816,19712,0.813648,0.988828476,0.900756239,1.085886555,0.899925844,DB0069510003549_,0.105442915,-0.011234394,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,1656,DB01098,10003549,244,7905,241,6968,0.229389797,0.892447393,0.741634603,1.074011431,0.385161508,DB0109810003549_,0.954092532,-0.113787711,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,1657,DB01136,10003549,329,9555,368,10747,0.969221815,1.005552301,0.861713728,1.173079509,1,DB0113610003549_,0,0.005536944,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,1658,DB06228,10003549,333,15579,213,15863,1.24219143060394e-07,1.591846603,1.334402037,1.90230915,2.21518896106513e-06,DB0622810003549_,13.02017285,0.464894728,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,1659,DB14513,10003549,261,6916,137,3427,0.587936348,0.944021191,0.761507573,1.174406787,0.73493791,DB1451310003549_,0.307969259,-0.057606665,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,1662,DB00169,10008796,56,38635,22,18153,0.544193422,1.195984696,0.718394456,2.057724341,0.699245917,DB0016910008796_,0.357752786,0.178969859,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,1665,DB00695,10008796,48,28001,31,20497,0.649006384,1.133395259,0.706538436,1.842786901,0.783913462,DB0069510008796_,0.243456645,0.125217782,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,1670,DB00115,10012735,1351,17074,582,9890,4.59762553749165e-09,1.344586971,1.215259737,1.48904941,1.11381186408265e-07,DB0011510012735_,16.01030741,0.296086881,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,1671,DB00126,10012735,702,9469,341,5604,0.003875019,1.218322128,1.064347626,1.396632523,0.016625297,DB0012610012735_,4.09682981,0.197474607,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,1672,DB00169,10012735,2517,36174,994,17181,1.42059073686911e-06,1.202644373,1.114527718,1.298516946,1.96217695841328e-05,DB0016910012735_,10.83887092,0.184522776,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,1673,DB00343,10012735,552,8184,256,4839,0.001797151,1.274903073,1.092485645,1.490819455,0.008906969,DB0034310012735_,4.72092126,0.242870155,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,1674,DB00542,10012735,111,1575,65,1359,0.015728132,1.473309886,1.065321578,2.05120249,0.051161927,DB0054210012735_,2.972759636,0.387511493,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,benazepril,DB00542
,1675,DB01098,10012735,509,7640,380,6829,0.010383112,1.197270892,1.041935693,1.376629653,0.036681486,DB0109810012735_,3.30548311,0.18004471,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,1676,DB01136,10012735,628,9256,505,10610,8.19036663709947e-09,1.425440002,1.261536316,1.61122886,1.87938705417861e-07,DB0113610012735_,15.48714996,0.354480539,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,1677,DB06228,10012735,628,15284,364,15712,3.44238197858335e-18,1.773542635,1.55322152,2.02752036,3.02113556951798e-16,DB0622810012735_,35.73572871,0.572979035,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,1678,DB14513,10012735,567,6610,206,3358,5.14470166021748e-05,1.398241366,1.183405673,1.65700269,0.000452723,DB1451310012735_,7.700229189,0.335215279,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,1679,DB00115,10016256,1671,16754,865,9607,0.019511637,1.10773627,1.015869553,1.208470664,0.060648899,DB0011510016256_,2.802653793,0.102318537,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,1680,DB00169,10016256,3208,35483,1346,16829,0.000267559,1.130401662,1.05750581,1.208737621,0.001838155,DB0016910016256_,6.298992929,0.122573023,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,1681,DB00343,10016256,606,8130,271,4824,0.000144801,1.326817898,1.142618411,1.543747128,0.001094647,DB0034310016256_,6.817323113,0.282783518,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,1682,DB00542,10016256,96,1590,81,1343,1,1.001071174,0.730093595,1.375297879,1,DB0054210016256_,0,0.0010706,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,benazepril,DB00542
,1683,DB01098,10016256,514,7635,458,6751,0.920669239,0.992331185,0.869399315,1.132860658,0.964846239,DB0109810016256_,0.035786528,-0.007698372,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,1684,DB01136,10016256,683,9201,656,10459,0.002963398,1.183497991,1.057758373,1.324271713,0.013367585,DB0113610016256_,4.3149225,0.168474453,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,1685,DB06228,10016256,632,15280,432,15644,1.45797594336104e-10,1.497785085,1.320416739,1.700273279,4.62836928396677e-09,DB0622810016256_,19.19106124,0.403987407,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,1686,DB14513,10016256,640,6537,259,3305,0.003463134,1.249253624,1.072961257,1.457752117,0.015195143,DB1451310016256_,4.18677945,0.222546273,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,1687,DB00115,10020937,347,18078,114,10358,1.1643421311094e-07,1.743982492,1.405356468,2.177426069,2.08550139122389e-06,DB0011510020937_,13.08050126,0.556171286,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,1688,DB00126,10020937,159,10012,57,5888,0.001073747,1.640425706,1.202712106,2.265009184,0.005840944,DB0012610020937_,5.142862843,0.494955785,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,1689,DB00169,10020937,668,38023,170,18005,3.45848065662249e-14,1.860672646,1.568500062,2.217147967,1.88602000123075e-12,DB0016910020937_,26.99655233,0.62093806,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,1690,DB00343,10020937,67,8669,38,5057,0.91949741,1.028524955,0.679662599,1.576770884,0.964382416,DB0034310020937_,0.036267366,0.028125693,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,1692,DB00695,10020937,309,27740,138,20390,8.33052251759236e-07,1.645828613,1.341134147,2.02807721,1.2206626553605e-05,DB0069510020937_,11.31353159,0.498243973,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,1693,DB01098,10020937,94,8055,50,7159,0.003241985,1.670817483,1.171462979,2.407975535,0.014410009,DB0109810020937_,4.239832253,0.513313018,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,1694,DB01136,10020937,93,9791,80,11035,0.078937621,1.310178509,0.959940819,1.791567286,0.176555085,DB0113610020937_,1.734122354,0.270163394,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,1695,DB06228,10020937,89,15823,65,16011,0.052225367,1.385479213,0.994220968,1.9395354,0.129211574,DB0622810020937_,2.046304107,0.326046082,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,1696,DB14513,10020937,105,7072,31,3533,0.010025205,1.692036228,1.121464911,2.619488907,0.035641107,DB1451310020937_,3.334255628,0.525932672,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,1697,DB00115,10024264,70,18355,53,10419,0.132190508,0.749738997,0.516794834,1.093267156,0.258923769,DB0011510024264_,1.351221591,-0.288030137,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,1698,DB00126,10024264,35,10136,39,5906,0.007429791,0.522921199,0.321263892,0.848269651,0.028079375,DB0012610024264_,3.572719974,-0.648324497,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,1699,DB00169,10024264,142,38549,77,18098,0.310075019,0.865806403,0.651139194,1.158645842,0.477515128,DB0016910024264_,0.739159437,-0.144093948,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,1700,DB00343,10024264,44,8692,24,5071,0.899829748,1.069586808,0.635448885,1.841279962,0.956571579,DB0034310024264_,0.044399659,0.067272413,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,1702,DB00695,10024264,161,27888,110,20418,0.621895049,1.07160392,0.835081036,1.379302766,0.762110651,DB0069510024264_,0.271663522,0.069156517,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,1703,DB01098,10024264,38,8111,19,7190,0.045594507,1.77283117,0.995930502,3.258838578,0.116717143,DB0109810024264_,2.148001853,0.5725778,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,1704,DB01136,10024264,47,9837,42,11073,0.288747228,1.259635273,0.812228118,1.959086367,0.45379497,DB0113610024264_,0.790109791,0.230822213,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,1705,DB06228,10024264,40,15872,36,16040,0.647039978,1.122867244,0.697333931,1.813965915,0.782313016,DB0622810024264_,0.245500343,0.115885453,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,1707,DB00115,10033775,281,18144,92,10380,1.66799090797398e-06,1.747329378,1.374235648,2.238859545,2.26228797812674e-05,DB0011510033775_,10.69654878,0.558088552,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,1708,DB00126,10033775,128,10043,52,5893,0.029325807,1.444342261,1.036807482,2.03751148,0.083215895,DB0012610033775_,2.486316906,0.367654035,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,1709,DB00169,10033775,548,38143,136,18039,1.68991057096797e-12,1.905613451,1.57518902,2.318483892,7.32387458497824e-11,DB0016910033775_,23.33729652,0.644803978,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,1710,DB00343,10033775,48,8688,24,5071,0.624481128,1.16737526,0.700125588,1.995037571,0.764285619,DB0034310033775_,0.268813712,0.154757861,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,1712,DB00695,10033775,256,27793,92,20436,1.07223012564105e-09,2.045988038,1.605019426,2.627456952,2.9604589130751e-08,DB0069510033775_,17.33533645,0.715880821,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,1713,DB01098,10033775,90,8059,49,7160,0.006133296,1.631786319,1.137989291,2.364123172,0.024083309,DB0109810033775_,3.726236233,0.489675316,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,1714,DB01136,10033775,79,9805,54,11061,0.005119682,1.650309256,1.151557616,2.380490349,0.020855609,DB0113610033775_,3.870132366,0.500962698,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,1715,DB06228,10033775,97,15815,65,16011,0.011494302,1.510774391,1.091290441,2.103238615,0.039808648,DB0622810033775_,3.223671095,0.412622361,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,1716,DB14513,10033775,97,7080,23,3541,0.00084457,2.109164218,1.325106611,3.489224704,0.004788032,DB1451310033775_,5.341635708,0.746291764,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,1717,DB00115,10054112,137,18288,81,10391,0.777622881,0.961032891,0.724114887,1.282361548,0.878753974,DB0011510054112_,0.129250314,-0.039746645,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,cyanocobalamin,DB00115
,1718,DB00126,10054112,91,10080,45,5900,0.373547604,1.183666287,0.818064365,1.734199753,0.543310024,DB0012610054112_,0.610075175,0.168616644,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,ascorbic acid,DB00126
,1719,DB00169,10054112,327,38364,206,17969,0.00107276,0.743479456,0.622038149,0.890298009,0.005836178,DB0016910054112_,5.143679222,-0.296414145,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,cholecalciferol,DB00169
,1720,DB00343,10054112,170,8566,55,5040,8.72872581353678e-05,1.818532548,1.331510818,2.517071627,0.000710434,DB0034310054112_,7.249634953,0.598029884,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,diltiazem,DB00343
,1722,DB00695,10054112,525,27524,285,20243,3.62781251398399e-05,1.354798494,1.16921177,1.572327163,0.00033541,DB0069510054112_,8.00015701,0.303652731,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,furosemide,DB00695
,1723,DB01098,10054112,70,8079,49,7160,0.230737329,1.266047968,0.865073751,1.865634037,0.386769383,DB0109810054112_,0.949926674,0.235900212,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,rosuvastatin,DB01098
,1724,DB01136,10054112,128,9756,130,10985,0.415315157,1.108644987,0.860321988,1.428418015,0.584554693,DB0113610054112_,0.536904929,0.103138537,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,carvedilol,DB01136
,1725,DB06228,10054112,255,15657,166,15910,7.56871304298139e-06,1.560935543,1.277130004,1.912006699,8.50186420234042e-05,DB0622810054112_,9.372640008,0.445285349,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,rivaroxaban,DB06228
,1726,DB14513,10054112,57,7120,31,3533,0.733215546,0.912392671,0.578012157,1.464943954,0.84519551,DB1451310054112_,0.168187305,-0.091684821,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,magnesium,DB14513
,1727,DB00115,10005483,76,18349,45,10427,0.849873217,0.95975104,0.654712843,1.421318209,0.925562657,DB0011510005483_,0.077353449,-0.041081362,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,1728,DB00213,10005483,118,18777,98,13323,0.267762821,0.854349354,0.647390672,1.129537285,0.430138778,DB0021310005483_,0.843647384,-0.157415089,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,pantoprazole,DB00213
,1729,DB00264,10005483,178,29429,215,24677,0.000362952,0.694233575,0.565530014,0.851388035,0.002364069,DB0026410005483_,6.047371121,-0.364946812,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,metoprolol,DB00264
,1730,DB00316,10005483,228,65246,262,36691,5.3606582028891e-15,0.489364806,0.407787517,0.586976085,3.26925524043944e-13,DB0031610005483_,28.74904401,-0.714647044,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,acetaminophen,DB00316
,1731,DB06228,10005483,52,15860,75,16001,0.050414173,0.69950811,0.481083274,1.010393787,0.125792519,DB0622810005483_,2.073121402,-0.357377891,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,rivaroxaban,DB06228
,1733,DB00213,10009802,24,18871,31,13390,0.028410589,0.549356019,0.308349781,0.967526941,0.081184142,DB0021310009802_,2.51103535,-0.599008561,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,pantoprazole,DB00213
,1734,DB00264,10009802,52,29555,73,24819,0.00514114,0.598195928,0.410738289,0.865837728,0.020917089,DB0026410009802_,3.867188792,-0.51383694,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,metoprolol,DB00264
,1735,DB00316,10009802,239,65235,170,36783,0.023104959,0.792728537,0.648212107,0.971167832,0.069162264,DB0031610009802_,2.671299884,-0.23227444,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,1736,DB00451,10009802,34,47237,33,15386,1.26297071840118e-05,0.335596968,0.201605252,0.559218364,0.000133242,DB0045110009802_,8.923345311,-1.091844338,male,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,levothyroxine,DB00451
,1737,DB06228,10009802,45,15867,58,16018,0.236782011,0.783253486,0.518245481,1.177127118,0.394086947,DB0622810009802_,0.931183716,-0.244298898,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,rivaroxaban,DB06228
,1744,DB00115,10021097,255,18170,196,10276,0.001555531,0.735819528,0.607402866,0.892406482,0.007920794,DB0011510021097_,4.838263782,-0.306770396,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,cyanocobalamin,DB00115
,1745,DB00213,10021097,381,18514,321,13100,0.024658149,0.839837848,0.7207708,0.979027109,0.072759255,DB0021310021097_,2.62059916,-0.174546443,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,pantoprazole,DB00213
,1746,DB00264,10021097,705,28902,757,24135,2.40981733558953e-06,0.777709103,0.69985709,0.864116655,3.11569349070196e-05,DB0026410021097_,10.37647371,-0.251402728,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,1747,DB00316,10021097,1086,64388,795,36158,2.40896354165398e-08,0.767138542,0.698741769,0.842465504,4.9681919727246e-07,DB0031610021097_,14.51503967,-0.265087866,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,1748,DB06228,10021097,286,15626,205,15871,0.000155454,1.416973671,1.178503263,1.706154003,0.001163139,DB0622810021097_,6.756633017,0.34852338,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,rivaroxaban,DB06228
,1750,DB00213,10023676,31,18864,26,13395,0.590990875,0.846645009,0.486219517,1.485309107,0.73746193,DB0021310023676_,0.304540812,-0.166473788,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,1751,DB00264,10023676,57,29550,50,24842,0.846387018,0.958353781,0.643748541,1.430819647,0.922855717,DB0026410023676_,0.080282377,-0.042538278,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,1752,DB00316,10023676,61,65413,54,36899,0.019298078,0.637189126,0.434434141,0.936919399,0.060114953,DB0031610023676_,2.811496671,-0.450688767,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,1753,DB00451,10023676,55,47216,53,15366,3.68466562901681e-08,0.337750266,0.227231073,0.502343539,7.30954234405335e-07,DB0045110023676_,14.12891499,-1.085448513,male,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,1755,DB00115,10035528,248,18177,220,10252,1.84194606619312e-06,0.635773177,0.527227152,0.767144833,2.46452289895069e-05,DB0011510035528_,10.61092723,-0.452913419,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,1756,DB00213,10035528,211,18684,170,13251,0.229118627,0.880268227,0.714924466,1.085157786,0.3848537,DB0021310035528_,0.954892018,-0.127528615,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,1757,DB00264,10035528,311,29296,292,24600,0.175138253,0.894346044,0.759168057,1.053826671,0.317658638,DB0026410035528_,1.146777938,-0.111662505,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,metoprolol,DB00264
,1758,DB00316,10035528,529,64945,432,36521,1.59112521658352e-08,0.688633932,0.604886615,0.784246158,3.40905474889733e-07,DB0031610035528_,14.8916606,-0.373045452,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,1759,DB00451,10035528,435,46836,194,15225,0.000394907,0.728899257,0.613392458,0.868676838,0.00253514,DB0045110035528_,5.977506389,-0.31621975,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,1760,DB06228,10035528,99,15813,106,15970,0.726175732,0.943215481,0.709229044,1.253566246,0.839676629,DB0622810035528_,0.174738427,-0.058460517,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,rivaroxaban,DB06228
,1762,DB00213,10038687,52,18843,34,13387,0.743376718,1.086585568,0.69147339,1.727714782,0.853241502,DB0021310038687_,0.15871265,0.083040273,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,1763,DB00264,10038687,66,29541,51,24841,0.710412859,1.088251649,0.743414277,1.601030665,0.827254491,DB0026410038687_,0.189642904,0.084572417,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,1764,DB00316,10038687,128,65346,89,36864,0.137316264,0.811354678,0.614036846,1.075990012,0.265980693,DB0031610038687_,1.324331557,-0.209049986,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,1765,DB00451,10038687,79,47192,52,15367,0.000145202,0.494689215,0.344084316,0.716526922,0.001096894,DB0045110038687_,6.815273108,-0.703825561,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,1767,DB00115,10047943,45,18380,39,10433,0.053958287,0.654995264,0.416746587,1.033448166,0.132420855,DB0011510047943_,2.021770132,-0.423127274,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,1768,DB00213,10047943,54,18841,47,13374,0.313358201,0.815565616,0.54099606,1.233365174,0.480908945,DB0021310047943_,0.73207733,-0.2038734,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,pantoprazole,DB00213
,1769,DB00264,10047943,82,29525,74,24818,0.687685575,0.931464183,0.671594025,1.293724846,0.811687484,DB0026410047943_,0.208639884,-0.07099754,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,metoprolol,DB00264
,1770,DB00316,10047943,149,65325,98,36855,0.259390707,0.85779007,0.660083163,1.118831078,0.42049306,DB0031610047943_,0.866327303,-0.153395884,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,acetaminophen,DB00316
,1771,DB00451,10047943,149,47122,39,15380,0.235740832,1.246953449,0.870923727,1.823645025,0.392876476,DB0045110047943_,0.934260028,0.220703335,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,levothyroxine,DB00451
,1773,DB00115,10060795,82,18343,34,10438,0.122732028,1.372389178,0.908957743,2.113307821,0.245326313,DB0011510060795_,1.405166065,0.316553147,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,1774,DB00213,10060795,70,18825,34,13387,0.072815983,1.464070706,0.958076891,2.276600964,0.166232284,DB0021310060795_,1.794369165,0.381220711,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,pantoprazole,DB00213
,1775,DB00264,10060795,120,29487,66,24826,0.005057714,1.530766942,1.123795029,2.100818234,0.020648198,DB0026410060795_,3.880127239,0.425768879,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,metoprolol,DB00264
,1776,DB00316,10060795,221,65253,126,36827,0.955358929,0.989888913,0.791500869,1.242454123,0.993161739,DB0031610060795_,0.006861749,-0.010162551,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,acetaminophen,DB00316
,1777,DB06228,10060795,44,15868,55,16021,0.314760983,0.807720506,0.5304068,1.223668595,0.482337566,DB0622810060795_,0.729111065,-0.213539188,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,rivaroxaban,DB06228
,1778,DB00115,10064355,75,18350,59,10413,0.071192373,0.721387554,0.505605281,1.033363366,0.1633745,DB0011510064355_,1.81171017,-0.326578763,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,1779,DB00213,10064355,74,18821,51,13370,0.927625173,1.03074443,0.711336695,1.503859094,0.969603836,DB0021310064355_,0.030867707,0.030281288,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,1780,DB00264,10064355,144,29463,104,24788,0.250365412,1.164909739,0.898408485,1.514726083,0.410098764,DB0026410064355_,0.891357261,0.152643607,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,1781,DB00316,10064355,241,65233,134,36819,0.914282211,1.015119016,0.818149232,1.263894894,0.961631513,DB0031610064355_,0.039123944,0.015005863,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,1782,DB00451,10064355,256,47015,81,15338,0.849256263,1.031081546,0.799547965,1.341583335,0.924967604,DB0045110064355_,0.077996565,0.030608296,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,1783,DB06228,10064355,228,15684,204,15872,0.208135641,1.131038973,0.931004677,1.374824597,0.358955798,DB0622810064355_,1.024556022,0.123136655,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,1784,DB14512,10013709,217,4627,106,2306,0.903889181,1.020264302,0.800536003,1.306631067,0.95743432,DB1451210013709_,0.043498156,0.020061713,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,1785,DB06228,10038460,20,15892,31,16045,0.160726538,0.651384628,0.351715646,1.180370555,0.298522968,DB0622810038460_,1.208908405,-0.428654985,NA,10038460,Renal haemorrhage,10038359,Renal and urinary disorders,Renal,rivaroxaban,DB06228
,1789,DB00476,10012378,711,16546,198,5979,0.001249403,1.297559023,1.1037312,1.530990206,0.006609753,DB0047610012378_,5.019208952,0.260484825,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,1790,DB00537,10012378,118,7439,46,4252,0.027325055,1.466187654,1.032185102,2.113504867,0.078706819,DB0053710012378_,2.54202548,0.3826656,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ciprofloxacin,DB00537
,1792,DB01062,10012378,100,4386,23,1722,0.019534494,1.706892828,1.072046425,2.825051785,0.060692455,DB0106210012378_,2.801935882,0.534674658,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,oxybutynin,DB01062
,1793,DB01273,10012378,97,1943,73,1202,0.225303945,0.822073986,0.595105353,1.139635894,0.380158826,DB0127310012378_,0.967166151,-0.19592488,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,varenicline,DB01273
,1810,DB00060,10060891,100,9408,28,2437,0.741496462,0.925119343,0.601616574,1.465135998,0.851752846,DB0006010060891_,0.160458881,-0.07783253,NA,10060891,General symptom,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,1811,DB08908,10060891,77,10596,25,3254,0.81483327,0.945857442,0.594418863,1.553177484,0.900608932,DB0890810060891_,0.104684153,-0.055663417,NA,10060891,General symptom,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,1813,DB00181,10012373,48,9808,64,5807,2.0775471406659e-05,0.444069634,0.298471254,0.656834774,0.000206459,DB0018110012373_,8.485410157,-0.811773897,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,1814,DB00327,10012373,41,6097,20,4242,0.239700129,1.42624365,0.815321108,2.573481366,0.397516634,DB0032710012373_,0.9225185,0.35504417,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,1825,DB00181,10064355,41,9815,35,5836,0.122828492,0.696571283,0.432253654,1.12792732,0.245451545,DB0018110064355_,1.404655722,-0.361585146,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,1833,DB00060,10057668,137,9371,44,2421,0.22805478,0.804424342,0.567090103,1.160565642,0.383446549,DB0006010057668_,0.958555046,-0.217628361,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,1834,DB08908,10057668,119,10554,44,3235,0.306501137,0.828988449,0.580602255,1.202623375,0.473500977,DB0890810057668_,0.747601302,-0.187549057,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,1853,DB00019,10002034,113,18899,43,9486,0.126202039,1.319052076,0.919861397,1.922033221,0.250422421,DB0001910002034_,1.384606101,0.276913354,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,pegfilgrastim,DB00019
,1854,DB00099,10002034,79,2306,64,1891,1,1.012228221,0.714465247,1.438679894,1,DB0009910002034_,0,0.01215406,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,filgrastim,DB00099
,1855,DB00316,10002034,997,64477,646,36307,0.00604916,0.86906316,0.785697019,0.961792872,0.023816981,DB0031610002034_,3.737356484,-0.140339475,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,1856,DB00377,10002034,74,1045,36,687,0.15940613,1.351140918,0.88416503,2.097024748,0.296668429,DB0037710002034_,1.215140164,0.30094936,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,palonosetron,DB00377
,1857,DB00399,10002034,194,6798,100,4898,0.006988937,1.397742449,1.089253294,1.802585587,0.026757586,DB0039910002034_,3.620937264,0.334858399,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,zoledronic acid,DB00399
,1858,DB00425,10002034,192,12503,113,7371,1,1.001693674,0.788400114,1.277560955,1,DB0042510002034_,0,0.001692242,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,zolpidem,DB00425
,1859,DB00531,10002034,247,7005,204,6312,0.388139808,1.090964975,0.899723197,1.324065996,0.558110222,DB0053110002034_,0.583198806,0.087062603,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,cyclophosphamide,DB00531
,1860,DB00581,10002034,61,2052,59,2010,1,1.012734803,0.692393122,1.482193979,1,DB0058110002034_,0,0.012654398,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,lactulose,DB00581
,1861,DB00889,10002034,40,740,21,496,0.422818619,1.276470277,0.724825801,2.308052492,0.591741203,DB0088910002034_,0.524685897,0.244098672,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,granisetron,DB00889
,1863,DB00996,10002034,447,38506,260,22165,0.90621502,0.989628952,0.846644754,1.158650947,0.958144782,DB0099610002034_,0.042756383,-0.010425202,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,gabapentin,DB00996
,1864,DB01075,10002034,267,19681,156,10941,0.645778542,0.951477827,0.776918925,1.168494803,0.781415075,DB0107510002034_,0.246648804,-0.049738896,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,diphenhydramine,DB01075
,1865,DB01101,10002034,95,7494,24,3884,0.001227183,2.051417251,1.297256631,3.363530129,0.006511862,DB0110110002034_,5.034129879,0.718530896,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,capecitabine,DB01101
,1866,DB01229,10002034,377,5364,97,2612,8.83750846638282e-09,1.89245071,1.502305552,2.402650059,2.01120268431924e-07,DB0122910002034_,15.41936276,0.637872661,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,paclitaxel,DB01229
,1867,DB01234,10002034,691,30934,569,32319,3.2011878121059e-05,1.268775245,1.132629978,1.421750163,0.000300458,DB0123410002034_,8.110203071,0.238052062,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,dexamethasone,DB01234
,1868,DB01248,10002034,81,2619,66,1308,0.004364592,0.612994481,0.434299851,0.867896427,0.018324943,DB0124810002034_,3.999492146,-0.489399347,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,docetaxel,DB01248
,1869,DB01590,10002034,105,4633,45,2822,0.050546422,1.421190358,0.989810026,2.069401096,0.126006019,DB0159010002034_,2.071425607,0.3514948,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,everolimus,DB01590
,1873,DB00316,10003246,357,65117,114,36839,3.58884281571842e-08,1.771635042,1.430369904,2.207976523,7.12752046929797e-07,DB0031610003246_,14.15413224,0.571902873,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,1875,DB00399,10003246,46,6946,18,4980,0.03028097,1.832135403,1.040500839,3.361513319,0.085295536,DB0039910003246_,2.461633155,0.605482173,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,1876,DB00425,10003246,51,12644,35,7449,0.503106453,0.858463227,0.546946311,1.361445194,0.664263267,DB0042510003246_,0.409076722,-0.152611434,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,1881,DB00996,10003246,207,38746,61,22364,1.57446213509054e-06,1.958656545,1.464840268,2.651997748,2.1509738680278e-05,DB0099610003246_,10.74700476,0.672258802,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,1882,DB01075,10003246,58,19890,20,11077,0.075290573,1.615024117,0.956433883,2.836487984,0.170318232,DB0107510003246_,1.770086637,0.479349889,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,1885,DB01234,10003246,91,31534,56,32832,0.002139112,1.691862045,1.199261377,2.405088762,0.010279382,DB0123410003246_,4.577615123,0.525829724,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,1889,DB00019,10008479,91,18921,37,9492,0.302507586,1.233782736,0.832556948,1.861970641,0.468851121,DB0001910008479_,0.757470001,0.210084845,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,1890,DB00099,10008479,41,2344,24,1931,0.209649074,1.407223526,0.826980527,2.444093479,0.360749299,DB0009910008479_,1.019572024,0.341618633,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,filgrastim,DB00099
,1891,DB00377,10008479,43,1076,23,700,0.521659948,1.216115744,0.709567757,2.134145435,0.680376182,DB0037710008479_,0.385109425,0.195661963,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,palonosetron,DB00377
,1892,DB00399,10008479,109,6883,41,4957,0.00031166,1.914518001,1.322846845,2.818429344,0.002082618,DB0039910008479_,6.174129312,0.649465895,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,1893,DB00531,10008479,72,7180,47,6469,0.096776425,1.38018155,0.941002441,2.041163651,0.20594813,DB0053110008479_,1.580130937,0.322215048,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,1894,DB00581,10008479,37,2076,32,2037,0.628930252,1.134493719,0.684669148,1.889056707,0.768064287,DB0058110008479_,0.263881842,0.126186489,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,lactulose,DB00581
,1897,DB01075,10008479,347,19601,161,10936,0.055708185,1.202454612,0.993121739,1.460994071,0.135554497,DB0107510008479_,1.998381529,0.184364977,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,1898,DB01101,10008479,109,7480,33,3875,0.005693317,1.711055687,1.147268007,2.613447913,0.022698141,DB0110110008479_,3.785472263,0.537110541,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,1899,DB01229,10008479,83,5658,39,2670,1,1.004296289,0.676478948,1.513867525,1,DB0122910008479_,0,0.004287086,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,1900,DB01248,10008479,47,2653,24,1350,1,0.996513853,0.59420965,1.711588168,1,DB0124810008479_,0,-0.003492237,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,1901,DB01590,10008479,37,4701,25,2842,0.693964512,0.894752898,0.52316506,1.554146434,0.815769362,DB0159010008479_,0.203623609,-0.111207691,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,1903,DB00019,10013573,132,18880,47,9482,0.04659131,1.410487014,1.002980017,2.013886672,0.118673635,DB0001910013573_,2.131378118,0.343935045,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pegfilgrastim,DB00019
,1904,DB00099,10013573,45,2340,33,1922,0.647721592,1.119992705,0.695875218,1.819577104,0.78282977,DB0009910013573_,0.244840014,0.113322171,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,filgrastim,DB00099
,1905,DB00316,10013573,1905,63569,879,36074,4.52577901136075e-07,1.229814033,1.133600653,1.335118358,7.08939817125252e-06,DB0031610013573_,11.85691011,0.206862965,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,1906,DB00377,10013573,62,1057,32,691,0.329474056,1.266456464,0.804216062,2.028112128,0.498143547,DB0037710013573_,0.696866997,0.236222815,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,palonosetron,DB00377
,1907,DB00399,10013573,242,6750,104,4894,6.83388127257022e-06,1.687029381,1.331014791,2.150469625,7.77949628624982e-05,DB0039910013573_,9.461433874,0.52296922,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,zoledronic acid,DB00399
,1908,DB00425,10013573,427,12268,203,7281,0.010544769,1.248344264,1.051078837,1.486592655,0.037131658,DB0042510013573_,3.293285356,0.221818084,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,1909,DB00531,10013573,113,7139,80,6436,0.110109561,1.273382418,0.945878819,1.721062684,0.226217744,DB0053110013573_,1.486257273,0.241676681,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,1910,DB00581,10013573,53,2060,60,2009,0.446930456,0.861495997,0.580775612,1.274764649,0.614734015,DB0058110013573_,0.486565601,-0.14908487,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lactulose,DB00581
,1911,DB00889,10013573,34,746,16,501,0.302719725,1.426734315,0.756824296,2.799482575,0.469052995,DB0088910013573_,0.757039521,0.355388137,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,granisetron,DB00889
,1913,DB01075,10013573,526,19422,243,10854,0.014770595,1.209727972,1.035172028,1.416801703,0.048719423,DB0107510013573_,3.021677503,0.190395518,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,1914,DB01101,10013573,132,7457,61,3847,0.539897328,1.11633789,0.815922021,1.542096145,0.695552748,DB0110110013573_,0.363048429,0.110053587,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,capecitabine,DB01101
,1915,DB01229,10013573,120,5621,55,2654,0.934792858,1.030190403,0.739978145,1.44953839,0.975176325,DB0122910013573_,0.025136978,0.029743643,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,paclitaxel,DB01229
,1916,DB01234,10013573,801,30824,678,32210,7.00564902007532e-05,1.234531255,1.111722364,1.371173758,0.000587286,DB0123410013573_,7.439998855,0.210691348,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,1917,DB01248,10013573,75,2625,24,1350,0.052105761,1.606970631,0.997690219,2.674646582,0.128970285,DB0124810013573_,2.048173252,0.474350811,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,docetaxel,DB01248
,1918,DB01590,10013573,75,4663,61,2806,0.089791673,0.739915297,0.518882658,1.058620449,0.194886597,DB0159010013573_,1.635337446,-0.301219563,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,everolimus,DB01590
,1920,DB00019,10015090,46,18966,11,9518,0.024160453,2.098578285,1.070145855,4.494964891,0.071600148,DB0001910015090_,2.63665814,0.741260108,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pegfilgrastim,DB00019
,1921,DB00099,10015090,30,2355,20,1935,0.567891664,1.232424504,0.674690523,2.297616786,0.718941958,DB0009910015090_,0.329974651,0.20898337,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,filgrastim,DB00099
,1922,DB00316,10015090,326,65148,213,36740,0.096323169,0.863136651,0.723686928,1.031226794,0.205213885,DB0031610015090_,1.5837025,-0.147182256,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,1923,DB00377,10015090,39,1080,14,709,0.062818416,1.828212604,0.962658666,3.673077248,0.148674776,DB0037710015090_,1.905994068,0.60333877,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,palonosetron,DB00377
,1924,DB00399,10015090,48,6944,38,4960,0.661438143,0.902264566,0.576279923,1.421626093,0.793514449,DB0039910015090_,0.23128353,-0.102847491,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zoledronic acid,DB00399
,1925,DB00425,10015090,53,12642,47,7437,0.048103253,0.663416793,0.438910595,1.005337881,0.121541287,DB0042510015090_,2.107501262,-0.410351839,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,1926,DB00531,10015090,53,7199,42,6474,0.60646053,1.134809502,0.741594034,1.74640754,0.749362558,DB0053110015090_,0.288532356,0.126464797,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclophosphamide,DB00531
,1930,DB00996,10015090,143,38810,84,22341,0.89029025,0.979967068,0.742937378,1.299450537,0.954589293,DB0099610015090_,0.04647409,-0.020236311,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,1931,DB01075,10015090,132,19816,60,11037,0.199906561,1.225292069,0.895624234,1.693177614,0.348884135,DB0107510015090_,1.053015402,0.203179239,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,1932,DB01101,10015090,46,7543,24,3884,1,0.986915368,0.58902953,1.693090419,1,DB0110110015090_,0,-0.01317099,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,capecitabine,DB01101
,1933,DB01229,10015090,74,5667,28,2681,0.338523212,1.250243792,0.797275203,2.011614768,0.50757723,DB0122910015090_,0.678106403,0.223338566,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,paclitaxel,DB01229
,1934,DB01234,10015090,185,31440,148,32740,0.01804206,1.301675953,1.042373144,1.627830213,0.056941291,DB0123410015090_,2.865734526,0.263652629,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,1935,DB01248,10015090,43,2657,9,1365,0.011532517,2.45407104,1.175525483,5.742881289,0.03990682,DB0124810015090_,3.221208041,0.897748295,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docetaxel,DB01248
,1936,DB01590,10015090,88,4650,62,2805,0.350783539,0.856214466,0.609440971,1.209157999,0.520517051,DB0159010015090_,0.652932632,-0.15523439,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,everolimus,DB01590
,1940,DB00316,10017533,166,65308,38,36915,6.9545474351037e-08,2.469203815,1.726519701,3.61265615,1.30292430029723e-06,DB0031610017533_,13.55089936,0.903895757,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,1948,DB00996,10017533,90,38863,20,22405,3.8770052503468e-05,2.594259185,1.584265635,4.449128076,0.000355325,DB0099610017533_,7.942478941,0.953300998,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,1949,DB01075,10017533,65,19883,11,11086,5.70489355082796e-05,3.294576401,1.724365669,6.927639123,0.000494242,DB0107510017533_,7.612484587,1.192277602,female,10017533,Fungal infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,1952,DB01234,10017533,67,31558,45,32843,0.023186455,1.54949368,1.045999532,2.314579107,0.069323319,DB0123410017533_,2.668973934,0.43792822,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,1956,DB00019,10019211,152,18860,52,9477,0.016947033,1.468804332,1.064363661,2.05530062,0.054252057,DB0001910019211_,2.914114377,0.38444869,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pegfilgrastim,DB00019
,1957,DB00099,10019211,68,2317,22,1933,6.06047398781346e-05,2.578045891,1.567066638,4.397219135,0.000520247,DB0009910019211_,7.561207315,0.947031705,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,filgrastim,DB00099
,1958,DB00316,10019211,3327,62147,979,35974,1.03494671410157e-82,1.967139236,1.828963668,2.117114409,1.51130968778665e-79,DB0031610019211_,181.4912457,0.676580323,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,1959,DB00377,10019211,55,1064,33,690,0.823111546,1.080796698,0.68151684,1.737276274,0.906103528,DB0037710019211_,0.09860171,0.077698452,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,palonosetron,DB00377
,1960,DB00399,10019211,270,6722,65,4933,2.04895271209542e-18,3.048017876,2.31085063,4.070603064,1.83186129379007e-16,DB0039910019211_,36.23602894,1.114491503,female,10019211,Headache,10029205,Nervous system disorders,Nerv,zoledronic acid,DB00399
,1961,DB00425,10019211,625,12070,218,7266,1.68677557963389e-12,1.725838282,1.472629864,2.028504121,7.31631949021071e-11,DB0042510019211_,23.33832862,0.545712893,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,1962,DB00531,10019211,185,7067,121,6395,0.006424439,1.383504239,1.091337157,1.759095055,0.025000574,DB0053110019211_,3.688856497,0.324619584,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,1963,DB00581,10019211,85,2028,39,2030,5.1123808645384e-05,2.181257317,1.468226445,3.290957498,0.000450634,DB0058110019211_,7.704856029,0.779901461,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lactulose,DB00581
,1964,DB00889,10019211,49,731,28,489,0.55041855,1.17049311,0.710059311,1.962891845,0.704634236,DB0088910019211_,0.350076426,0.157425122,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,granisetron,DB00889
,1966,DB00996,10019211,1639,37314,499,21926,1.69420019139272e-40,1.93001589,1.742419563,2.140742711,6.74728061072085e-38,DB0099610019211_,85.58909398,0.657528236,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,1967,DB01075,10019211,1226,18722,383,10714,4.76845313691456e-26,1.831819212,1.6277348,2.064984251,7.88294281155969e-24,DB0107510019211_,53.19734094,0.605309578,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,1968,DB01101,10019211,157,7432,32,3876,1.60648129593627e-07,2.558568178,1.73669438,3.876858184,2.79182551164858e-06,DB0110110019211_,12.78881487,0.939447796,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,capecitabine,DB01101
,1969,DB01229,10019211,124,5617,25,2684,2.70851297360262e-05,2.369860033,1.528367731,3.812483758,0.00025912,DB0122910019211_,8.258218672,0.862830896,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,paclitaxel,DB01229
,1970,DB01234,10019211,702,30923,386,32502,3.87950987872451e-25,1.911483675,1.684199714,2.171980026,5.98081625585183e-23,DB0123410019211_,51.17090008,0.647879734,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,1971,DB01248,10019211,88,2612,29,1345,0.037516353,1.56239097,1.010631022,2.479537978,0.10060882,DB0124810019211_,2.296515349,0.446217321,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,docetaxel,DB01248
,1972,DB01590,10019211,164,4574,91,2776,0.511888235,1.09377173,0.837581381,1.43561283,0.672160972,DB0159010019211_,0.397257426,0.089632026,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,everolimus,DB01590
,1976,DB00316,10024384,111,65363,73,36880,0.318317596,0.857951756,0.632653912,1.169467017,0.486310841,DB0031610024384_,0.720907269,-0.153207409,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,1980,DB00531,10024384,51,7201,38,6478,0.396051187,1.207336689,0.776695639,1.891356016,0.565679805,DB0053110024384_,0.569727076,0.18841685,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,cyclophosphamide,DB00531
,1984,DB00996,10024384,54,38899,34,22391,0.739801313,0.914221209,0.584263052,1.448736299,0.85036307,DB0099610024384_,0.162091879,-0.089682714,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,gabapentin,DB00996
,1985,DB01075,10024384,40,19908,25,11072,0.69783474,0.889860141,0.526454777,1.531320963,0.818262715,DB0107510024384_,0.200571827,-0.116690973,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,diphenhydramine,DB01075
,1987,DB01229,10024384,40,5701,18,2691,1,1.048932532,0.586387677,1.94763507,1,DB0122910024384_,0,0.047773011,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,paclitaxel,DB01229
,1988,DB01234,10024384,96,31529,88,32800,0.416909014,1.134882908,0.840544744,1.533866133,0.586073629,DB0123410024384_,0.534309851,0.126529481,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,dexamethasone,DB01234
,1994,DB00316,10027457,55,65419,15,36938,0.012171621,2.070320701,1.153041516,3.94639996,0.04162517,DB0031610027457_,3.179050235,0.727703523,NA,10027457,Metastases to liver,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,2004,DB01101,10027457,63,7526,18,3890,0.025133025,1.808977853,1.055808088,3.251285274,0.073783612,DB0110110027457_,2.606618637,0.592761964,NA,10027457,Metastases to liver,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,capecitabine,DB01101
,2005,DB01229,10027457,71,5670,11,2698,0.000181635,3.070998227,1.613479467,6.439124953,0.00132988,DB0122910027457_,6.622666408,1.122002664,female,10027457,Metastases to liver,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,paclitaxel,DB01229
,2006,DB01234,10027457,50,31575,16,32872,1.11726163972557e-05,3.253507927,1.821671218,6.122189272,0.000119452,DB0123410027457_,9.032597712,1.179733776,female,10027457,Metastases to liver,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,2008,DB01590,10027457,45,4693,11,2856,0.005197132,2.489325476,1.265090778,5.346176754,0.021105695,DB0159010027457_,3.858212377,0.912011781,NA,10027457,Metastases to liver,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,everolimus,DB01590
,2012,DB00316,10028116,78,65396,52,36901,0.361501425,0.846413899,0.588228646,1.226716183,0.53139082,DB0031610028116_,0.632257521,-0.166746797,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,2016,DB00531,10028116,95,7157,188,6328,7.51445750125702e-11,0.446810687,0.344553445,0.576275348,2.50339056299798e-09,DB0053110028116_,19.8056198,-0.805620294,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,2021,DB01075,10028116,44,19904,31,11066,0.335026015,0.789138821,0.486862787,1.29339637,0.50419564,DB0107510028116_,0.684790912,-0.236813028,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,2022,DB01101,10028116,58,7531,42,3866,0.090856543,0.708900493,0.467463348,1.083172159,0.196597178,DB0110110028116_,1.626598425,-0.344040111,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,2023,DB01229,10028116,52,5689,28,2681,0.550136278,0.875219345,0.541246877,1.442713147,0.704490316,DB0122910028116_,0.350280694,-0.133280744,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,2024,DB01234,10028116,80,31545,121,32767,0.008916039,0.686775922,0.510951786,0.918851803,0.032473063,DB0123410028116_,3.427344374,-0.375747209,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,2025,DB01248,10028116,50,2650,36,1338,0.108023548,0.701297918,0.445406517,1.114057515,0.223082886,DB0124810028116_,1.500211893,-0.354822493,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,2026,DB01590,10028116,51,4687,9,2858,0.00014556,3.454914702,1.681342224,7.995430718,0.001098649,DB0159010028116_,6.813674154,1.239797769,female,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,2028,DB00019,10028813,296,18716,117,9412,0.031039705,1.27229349,1.022166771,1.592012786,0.086999403,DB0001910028813_,2.441854027,0.24082117,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pegfilgrastim,DB00019
,2029,DB00099,10028813,166,2219,73,1882,3.41056614881677e-06,1.928339506,1.445156646,2.593526091,4.2246338935744e-05,DB0009910028813_,10.07199286,0.656659273,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,filgrastim,DB00099
,2030,DB00377,10028813,248,871,114,609,0.000760768,1.520716102,1.183805234,1.96148435,0.00438478,DB0037710028813_,5.429615739,0.419181343,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,palonosetron,DB00377
,2031,DB00399,10028813,498,6494,146,4852,2.47477294616866e-25,2.548261672,2.106605392,3.097738039,3.87198850535971e-23,DB0039910028813_,51.60568894,0.935411429,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,2032,DB00531,10028813,409,6843,258,6258,4.62216982924174e-06,1.449704053,1.232676398,1.707271164,5.52621032347597e-05,DB0053110028813_,9.803423178,0.371359434,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,2033,DB00581,10028813,139,1974,118,1951,0.246882345,1.164197576,0.896806452,1.513285678,0.405987416,DB0058110028813_,0.901433115,0.152032074,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lactulose,DB00581
,2034,DB00889,10028813,174,606,84,433,0.008495239,1.479637885,1.100390705,2.00024808,0.031250067,DB0088910028813_,3.465733758,0.391797386,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,granisetron,DB00889
,2036,DB01075,10028813,1346,18602,480,10617,7.74707988711053e-19,1.600440273,1.437012582,1.784849119,7.22099272456384e-17,DB0107510028813_,37.16695414,0.470278762,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,2037,DB01101,10028813,719,6870,311,3597,0.007149864,1.210405274,1.051600393,1.395639064,0.027242758,DB0110110028813_,3.602967546,0.190955241,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,2038,DB01229,10028813,543,5198,170,2539,5.67931718437503e-07,1.560112501,1.301945541,1.876752262,8.68416824847573e-06,DB0122910028813_,11.65400893,0.444757935,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,paclitaxel,DB01229
,2039,DB01248,10028813,289,2411,98,1276,0.000188582,1.560560021,1.223751271,2.003189403,0.001371765,DB0124810028813_,6.591657339,0.445044744,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,docetaxel,DB01248
,2040,DB01590,10028813,324,4414,162,2705,0.042144227,1.225595863,1.005453315,1.498542607,0.109977109,DB0159010028813_,2.207483037,0.203427145,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,everolimus,DB01590
,2042,DB00019,10029354,245,18767,101,9428,0.096637939,1.218585767,0.96132881,1.554260563,0.205720042,DB0001910029354_,1.581239053,0.197690979,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,pegfilgrastim,DB00019
,2043,DB00099,10029354,152,2233,119,1836,0.705772377,1.050221033,0.813955203,1.357514782,0.823674283,DB0009910029354_,0.193980115,0.04900065,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,filgrastim,DB00099
,2044,DB00316,10029354,424,65050,357,36596,3.4670940828362e-08,0.668198155,0.578698758,0.771814897,6.91183678174816e-07,DB0031610029354_,14.18486023,-0.40317051,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,2045,DB00377,10029354,66,1053,33,690,0.244738256,1.310353761,0.840016229,2.078444077,0.403496522,DB0037710029354_,0.90758741,0.270297148,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,palonosetron,DB00377
,2046,DB00399,10029354,165,6827,106,4892,0.417974523,1.115433715,0.866110873,1.441566731,0.587008994,DB0039910029354_,0.532715137,0.109243311,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,zoledronic acid,DB00399
,2047,DB00425,10029354,85,12610,61,7423,0.263570793,0.820281339,0.582681727,1.160674447,0.425406546,DB0042510029354_,0.854709988,-0.198107901,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,zolpidem,DB00425
,2048,DB00531,10029354,356,6896,353,6163,0.189157653,0.901309121,0.772554549,1.051541197,0.33548186,DB0053110029354_,1.092187392,-0.103906994,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,cyclophosphamide,DB00531
,2049,DB00581,10029354,22,2091,33,2036,0.135320753,0.649201723,0.35926607,1.151878489,0.263133419,DB0058110029354_,1.335094079,-0.43201179,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,lactulose,DB00581
,2052,DB00996,10029354,234,38719,165,22260,0.047467099,0.815342676,0.664694581,1.001957482,0.120338802,DB0099610029354_,2.117444164,-0.204146793,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,gabapentin,DB00996
,2053,DB01075,10029354,167,19781,115,10982,0.080534719,0.806235839,0.631227443,1.032696429,0.179288141,DB0107510029354_,1.71876104,-0.215378975,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,diphenhydramine,DB01075
,2054,DB01101,10029354,95,7494,45,3863,0.719649516,1.088222897,0.753818297,1.591571672,0.834534998,DB0110110029354_,0.180880598,0.084545996,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,capecitabine,DB01101
,2055,DB01229,10029354,249,5492,111,2598,0.64446866,1.061166158,0.840773271,1.346135596,0.780476932,DB0122910029354_,0.247850094,0.059368452,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,paclitaxel,DB01229
,2056,DB01234,10029354,641,30984,616,32272,0.162715211,1.083819331,0.967761097,1.213898593,0.300983063,DB0123410029354_,1.200701286,0.08049122,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,dexamethasone,DB01234
,2057,DB01248,10029354,115,2585,61,1313,0.807001952,0.957593344,0.690742979,1.338330913,0.895703333,DB0124810029354_,0.110146023,-0.043332076,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,docetaxel,DB01248
,2058,DB01590,10029354,42,4696,9,2858,0.003291173,2.8398078,1.35997841,6.645367009,0.014585818,DB0159010029354_,4.227705617,1.043736374,female,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,everolimus,DB01590
,2078,DB00019,10033425,158,18854,45,9484,0.000559235,1.766138338,1.259758397,2.520163897,0.003386058,DB0001910033425_,5.68808888,0.568795433,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,pegfilgrastim,DB00019
,2079,DB00099,10033425,40,2345,22,1933,0.156889254,1.498601135,0.866080167,2.657311468,0.293326507,DB0009910033425_,1.226468932,0.404532096,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,filgrastim,DB00099
,2080,DB00377,10033425,42,1077,28,695,0.901219479,0.967963873,0.579904299,1.637950015,0.956927891,DB0037710033425_,0.044027239,-0.032560514,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,palonosetron,DB00377
,2081,DB00399,10033425,275,6717,70,4928,1.81170354549137e-17,2.881937769,2.203279827,3.812340329,1.47660861064312e-15,DB0039910033425_,34.14902842,1.058462904,female,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,2082,DB00531,10033425,83,7169,27,6489,1.1027768711757e-06,2.782129273,1.780552865,4.47531453,1.55967124341422e-05,DB0053110033425_,11.06845041,1.02321656,female,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclophosphamide,DB00531
,2083,DB00581,10033425,50,2063,32,2037,0.058468152,1.54264156,0.965956802,2.495631895,0.140639247,DB0058110033425_,1.961557196,0.433496245,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,lactulose,DB00581
,2086,DB01075,10033425,353,19595,142,10955,0.00091839,1.389789557,1.138928252,1.703234605,0.005137787,DB0107510033425_,5.271132931,0.329152338,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,2087,DB01101,10033425,230,7359,84,3824,0.006467569,1.422771099,1.099936697,1.855064266,0.025136781,DB0110110033425_,3.683423141,0.352606448,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,capecitabine,DB01101
,2088,DB01229,10033425,106,5635,32,2677,0.026930365,1.573580556,1.047759274,2.422285575,0.07786005,DB0122910033425_,2.552842289,0.453353632,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,paclitaxel,DB01229
,2089,DB01248,10033425,69,2631,19,1355,0.016207525,1.870055101,1.106748974,3.305759983,0.052361702,DB0124810033425_,2.949579842,0.625967896,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,docetaxel,DB01248
,2090,DB01590,10033425,79,4659,46,2821,0.853052711,1.039868994,0.711641575,1.53482446,0.928180234,DB0159010033425_,0.074529347,0.039094738,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,everolimus,DB01590
,2094,DB00316,10040882,93,65381,65,36888,0.185647936,0.807255167,0.581584987,1.126205196,0.330987994,DB0031610040882_,1.105673176,-0.214115469,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,2102,DB00996,10040882,62,38891,38,22387,0.756175229,0.939194658,0.617065216,1.44631159,0.863332214,DB0099610040882_,0.146955709,-0.062732518,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,2106,DB01234,10040882,55,31570,43,32845,0.188436902,1.330715783,0.876455424,2.032372543,0.33454216,DB0123410040882_,1.094992367,0.28571698,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,2112,DB00316,10047340,246,65228,66,36887,1.52559724182595e-08,2.107788605,1.599812758,2.810406112,3.28287544014696e-07,DB0031610047340_,14.92937595,0.745639343,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,acetaminophen,DB00316
,2115,DB00425,10047340,64,12631,17,7467,0.002519152,2.225479273,1.28653739,4.056945451,0.011729362,DB0042510047340_,4.445659992,0.799972296,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,zolpidem,DB00425
,2120,DB00996,10047340,172,38781,40,22385,2.58726827723701e-08,2.481990711,1.750075122,3.596334038,5.29252017756463e-07,DB0099610047340_,14.45180111,0.909060944,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,gabapentin,DB00996
,2121,DB01075,10047340,61,19887,15,11082,0.003708693,2.266089235,1.271713432,4.295235648,0.016046582,DB0107510047340_,4.132259403,0.818055542,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,diphenhydramine,DB01075
,2124,DB01234,10047340,59,31566,41,32847,0.056650823,1.497403742,0.988083097,2.288818462,0.137206119,DB0123410047340_,1.986270965,0.403732769,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,dexamethasone,DB01234
,2128,DB00019,10047700,183,18829,65,9464,0.017739861,1.415077481,1.059532162,1.91029259,0.056244165,DB0001910047700_,2.878052975,0.347184286,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pegfilgrastim,DB00019
,2129,DB00099,10047700,100,2285,48,1907,0.00179468,1.738476764,1.213270042,2.520420783,0.008899758,DB0009910047700_,4.721731154,0.553009307,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,filgrastim,DB00099
,2130,DB00316,10047700,2392,63082,985,35968,6.97702917937778e-18,1.384632073,1.283613505,1.494526801,5.944609788653e-16,DB0031610047700_,35.0588766,0.325434453,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,2131,DB00377,10047700,144,975,70,653,0.037338274,1.377523628,1.009750811,1.892708746,0.100259121,DB0037710047700_,2.29999723,0.320287415,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,palonosetron,DB00377
,2132,DB00399,10047700,262,6730,79,4919,5.1782526309847e-13,2.423822723,1.872505741,3.166860287,2.4047768622868e-11,DB0039910047700_,24.4509789,0.885345931,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,2133,DB00425,10047700,437,12258,148,7336,9.84249718239662e-10,1.767044683,1.459786912,2.148658726,2.73622462653935e-08,DB0042510047700_,17.41410165,0.569308481,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,2134,DB00531,10047700,255,6997,233,6283,0.853654314,0.982740055,0.816823468,1.1828435,0.928660858,DB0053110047700_,0.074011668,-0.017410634,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,2135,DB00581,10047700,92,2021,87,1982,0.819197094,1.037065855,0.759825194,1.416325658,0.903627158,DB0058110047700_,0.10133844,0.036395432,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lactulose,DB00581
,2136,DB00889,10047700,109,671,53,464,0.048781831,1.421774926,0.992021683,2.05727909,0.122771403,DB0088910047700_,2.097431165,0.351906039,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,granisetron,DB00889
,2138,DB00996,10047700,1138,37815,418,22007,2.66249765769643e-16,1.584380189,1.413340716,1.778869308,1.90173236229757e-14,DB0099610047700_,31.59342606,0.460193283,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,2139,DB01075,10047700,733,19215,315,10782,8.21682545289403e-05,1.305716042,1.140183752,1.497977688,0.000674514,DB0107510047700_,7.301518709,0.266751581,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,2140,DB01229,10047700,357,5384,109,2600,2.69910628563898e-05,1.581569186,1.265914416,1.98856002,0.000258314,DB0122910047700_,8.261333692,0.45841751,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,paclitaxel,DB01229
,2141,DB01234,10047700,860,30765,567,32321,7.80216228415308e-18,1.593443768,1.4297894,1.776911683,6.58362233190895e-16,DB0123410047700_,34.95677639,0.465897566,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,2142,DB01248,10047700,184,2516,71,1303,0.040288255,1.34203317,1.006357091,1.805572048,0.106225693,DB0124810047700_,2.242189268,0.294185755,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,docetaxel,DB01248
,2143,DB01590,10047700,175,4563,97,2770,0.524135754,1.095208229,0.845688258,1.425063125,0.682244697,DB0159010047700_,0.382366892,0.090944509,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,everolimus,DB01590
,2147,DB00316,10051398,219,65255,336,36617,1.39052912405366e-31,0.365743957,0.306941766,0.435155137,3.43193033105639e-29,DB0031610051398_,65.54184482,-1.005821761,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,2149,DB00399,10051398,63,6929,62,4936,0.082809695,0.723889157,0.500591822,1.047029727,0.183081237,DB0039910051398_,1.697825308,-0.323116996,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,zoledronic acid,DB00399
,2150,DB00425,10051398,45,12650,59,7425,5.81901709251208e-05,0.44769184,0.296487985,0.671976148,0.000502638,DB0042510051398_,7.595639539,-0.80365014,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,zolpidem,DB00425
,2151,DB00531,10051398,134,7118,142,6374,0.180302737,0.84503885,0.660654246,1.080401125,0.324224221,DB0053110051398_,1.126319961,-0.168372676,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyclophosphamide,DB00531
,2155,DB00996,10051398,100,38853,101,22324,9.10585057867646e-05,0.568920673,0.426887275,0.758023179,0.000736227,DB0099610051398_,7.213972544,-0.56401427,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,gabapentin,DB00996
,2156,DB01075,10051398,50,19898,46,11051,0.014156222,0.603658802,0.396042492,0.922048545,0.047020903,DB0107510051398_,3.057163036,-0.504746138,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,diphenhydramine,DB01075
,2157,DB01101,10051398,108,7481,22,3886,1.56022647012294e-05,2.549845002,1.598111316,4.244021226,0.00016026,DB0110110051398_,8.738712604,0.936032574,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,capecitabine,DB01101
,2158,DB01229,10051398,111,5630,53,2656,0.932843909,0.988023662,0.703587511,1.402451035,0.97356821,DB0122910051398_,0.02678739,-0.012048633,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,paclitaxel,DB01229
,2159,DB01234,10051398,143,31482,165,32723,0.391526837,0.900839082,0.714618749,1.134465383,0.56136822,DB0123410051398_,0.577378224,-0.104428637,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,2160,DB01248,10051398,47,2653,46,1328,0.001747653,0.511521295,0.331400204,0.789933971,0.00869773,DB0124810051398_,4.744693215,-0.670366063,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,docetaxel,DB01248
,2161,DB01590,10051398,253,4485,134,2733,0.215655049,1.15053254,0.924192194,1.437194396,0.368233021,DB0159010051398_,0.999039332,0.140224913,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,everolimus,DB01590
,2183,DB00316,10056342,103,65371,50,36903,0.400671694,1.162883165,0.821556662,1.665062036,0.570533057,DB0031610056342_,0.561184167,0.150902409,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,2191,DB00996,10056342,60,38893,29,22396,0.50889182,1.191351152,0.75249678,1.925884879,0.669437756,DB0099610056342_,0.401317089,0.175088085,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,2195,DB01234,10056342,41,31584,32,32856,0.242298547,1.332839343,0.818812695,2.187184654,0.400531894,DB0123410056342_,0.914961879,0.287311511,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,2217,DB01164,10035664,139,6385,173,7763,0.863124443,0.976870463,0.773751125,1.231470497,0.936733871,DB0116410035664_,0.06535606,-0.023401223,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,calcium chloride,DB01164
,2218,DB00678,10025482,521,15078,178,10546,1.37767810686294e-17,2.047141105,1.720223769,2.44518973,1.13340435176502e-15,DB0067810025482_,34.41355059,0.716444237,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,2222,DB00820,10013968,2565,9350,807,5009,1.44057373609346e-35,1.702707728,1.561056002,1.85848527,4.64607124579345e-33,DB0082010013968_,74.4492861,0.532219765,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,2225,DB01202,10001497,78,6636,89,5629,0.060678046,0.743434924,0.540240107,1.021299227,0.144661572,DB0120210001497_,1.933358249,-0.296474044,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,2226,DB01234,10001497,44,31581,69,32819,0.037849188,0.662685913,0.443221772,0.981518325,0.101351459,DB0123410001497_,2.289161013,-0.411454137,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,2227,DB01202,10022998,69,6645,45,5673,0.186137757,1.309014474,0.884735505,1.953735128,0.331607925,DB0120210022998_,1.103801958,0.269274545,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,2228,DB01234,10022998,47,31578,67,32821,0.11064178,0.729111199,0.491010407,1.074904583,0.227044984,DB0123410022998_,1.482607114,-0.315929023,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,2229,DB00188,10033661,77,7809,108,8720,0.138610602,0.796149287,0.585494168,1.078254315,0.267846329,DB0018810033661_,1.317341864,-0.227968564,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,bortezomib,DB00188
,2230,DB00399,10033661,61,6931,75,4923,0.001582536,0.577741462,0.404329852,0.822700871,0.008024607,DB0039910033661_,4.825242527,-0.548628808,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,zoledronic acid,DB00399
,2231,DB00480,10033661,479,66949,565,67097,0.009048482,0.849663705,0.750339882,0.961826463,0.032868899,DB0048010033661_,3.415228383,-0.162914649,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,lenalidomide,DB00480
,2232,DB00695,10033661,167,27882,145,20383,0.135119933,0.841968764,0.669473028,1.059944215,0.262840144,DB0069510033661_,1.336209249,-0.172012363,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,furosemide,DB00695
,2233,DB01234,10033661,292,31333,397,32491,0.000482458,0.762704687,0.652939477,0.890093258,0.003001519,DB0123410033661_,5.808636657,-0.270884365,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,dexamethasone,DB01234
,2234,DB00005,10046735,1071,127011,185,42234,1.37291161118616e-18,1.925139066,1.644824166,2.263307708,1.25084858578954e-16,DB0000510046735_,36.6175393,0.654998207,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,2236,DB00476,10002855,1561,15696,487,5690,0.005385727,1.161960411,1.044086883,1.294817342,0.021703654,DB0047610002855_,3.830274633,0.150108588,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,2237,DB00476,10013573,1812,15445,622,5555,0.35579633,1.047761908,0.951076344,1.155396025,0.525473046,DB0047610013573_,0.643456382,0.046656373,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,2238,DB00476,10019211,2019,15238,504,5673,3.13591329106436e-15,1.491364183,1.345476262,1.655317685,1.97905116099944e-13,DB0047610019211_,29.25098869,0.39969126,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,2240,DB00008,10002034,178,1347,161,1515,0.065625588,1.243390954,0.98618537,1.568594854,0.153521589,DB0000810002034_,1.873914076,0.217842287,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,peginterferon alfa-2a,DB00008
,2241,DB00811,10002034,288,2510,365,3791,0.036069622,1.191697048,1.009160447,1.40633105,0.097660454,DB0081110002034_,2.326258569,0.175378382,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ribavirin,DB00811
,2243,DB00008,10013968,74,1451,72,1604,0.497599944,1.136104789,0.803480175,1.607117709,0.659693569,DB0000810013968_,0.415979842,0.12760556,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,peginterferon alfa-2a,DB00008
,2244,DB00811,10013968,138,2660,148,4008,0.005519639,1.404857445,1.099971216,1.793323932,0.022140043,DB0081110013968_,3.810367416,0.339935835,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ribavirin,DB00811
,2246,DB00008,10037844,144,1381,133,1543,0.131452427,1.209639432,0.938055722,1.560716738,0.257815989,DB0000810037844_,1.355509169,0.190322325,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,peginterferon alfa-2a,DB00008
,2247,DB00811,10037844,203,2595,229,3927,0.003297057,1.341397965,1.097630387,1.638429331,0.014605395,DB0081110037844_,4.226364269,0.293712328,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ribavirin,DB00811
,2249,DB00008,10043554,33,1492,46,1630,0.306448104,0.783805751,0.482685383,1.260278101,0.473474704,DB0000810043554_,0.747656791,-0.243594056,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,peginterferon alfa-2a,DB00008
,2250,DB00811,10043554,41,2757,60,4096,1,1.015211843,0.663259998,1.540362243,1,DB0081110043554_,0,0.015097303,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,ribavirin,DB00811
,2255,DB00331,10018358,39,24907,52,20700,0.026772511,0.623333219,0.400490221,0.962927262,0.07749941,DB0033110018358_,2.557484951,-0.472674041,NA,10018358,Glomerular filtration rate decreased,10022891,Investigations,Inv,metformin,DB00331
,2256,DB00381,10018358,28,29332,30,22857,0.235388477,0.727313506,0.418565621,1.26016986,0.392500784,DB0038110018358_,0.935216743,-0.318397661,NA,10018358,Glomerular filtration rate decreased,10022891,Investigations,Inv,amlodipine,DB00381
,2258,DB01076,10018358,24,25723,43,25540,0.020088888,0.554178535,0.321537941,0.934219644,0.061973728,DB0107610018358_,2.781044721,-0.590268378,NA,10018358,Glomerular filtration rate decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,2261,DB00331,10061822,123,24823,70,20682,0.01111889,1.463999271,1.082294445,1.993639847,0.03873559,DB0033110061822_,3.250996457,0.381171918,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,2262,DB00381,10061822,235,29125,137,22750,0.006379321,1.339861427,1.079949564,1.667705026,0.024865492,DB0038110061822_,3.694274309,0.292566196,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,2263,DB00999,10061822,170,21260,51,12188,2.35603799016057e-05,1.910908666,1.388763515,2.669432669,0.000229651,DB0099910061822_,8.378949134,0.64757887,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,2264,DB01076,10061822,204,25543,171,25412,0.108012108,1.186858746,0.963063993,1.464077096,0.223068023,DB0107610061822_,1.500278517,0.171310108,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,2269,DB00188,10011906,189,7697,300,8528,0.000131565,0.698034493,0.577198865,0.842472815,0.001007778,DB0018810011906_,6.900006968,-0.359486761,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,2270,DB00264,10013709,1076,28531,859,24033,0.254927311,1.055153376,0.962100724,1.157429221,0.415628605,DB0026410013709_,0.877963193,0.053686137,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,2271,DB00635,10013709,2421,30632,1378,22416,3.9062674226506e-13,1.285659714,1.20014716,1.377605747,1.85002232800668e-11,DB0063510013709_,24.71323831,0.251271983,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,2272,DB00758,10013709,302,7998,311,9763,0.03908707,1.185340702,1.005534078,1.39717062,0.103814846,DB0075810013709_,2.265146292,0.170030245,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,2274,DB01076,10013709,1027,24720,929,24654,0.035887508,1.102529718,1.006130879,1.208321561,0.097312958,DB0107610013709_,2.329823123,0.097607283,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,2275,DB08899,10013709,19,230,533,7600,0.515134582,1.177884612,0.690639289,1.900830085,0.674980527,DB0889910013709_,0.393071437,0.163720128,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,enzalutamide,DB08899
,2276,DB00264,10061818,294,29313,279,24613,0.151774945,0.884807648,0.747847348,1.046991155,0.286407797,DB0026410061818_,1.25033862,-0.122385004,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,2277,DB00635,10061818,267,32786,379,23415,6.55937252799601e-18,0.503125604,0.42818478,0.590532104,5.59782814605114e-16,DB0063510061818_,35.1189828,-0.686915431,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,2278,DB00758,10061818,42,8258,59,10015,0.48453482,0.863331371,0.566324351,1.305790429,0.648694768,DB0075810061818_,0.432792984,-0.146956686,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,2280,DB01076,10061818,198,25549,252,25331,0.009160897,0.779016015,0.642844637,0.942913008,0.033190101,DB0107610061818_,3.4055036,-0.249723675,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,2282,DB00398,10011906,59,668,151,1387,0.214407899,0.811330077,0.581624418,1.120138197,0.366753107,DB0039810011906_,1.00306639,-0.209080307,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sorafenib,DB00398
,2285,DB00451,10025482,1643,45628,307,15112,5.6978825214885e-22,1.772576231,1.565959538,2.011663706,7.25272842989468e-20,DB0045110025482_,44.07032413,0.572433986,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,2286,DB00451,10000059,679,46592,152,15267,1.37818054716037e-05,1.463712531,1.224691546,1.75865728,0.00014398,DB0045110000059_,8.845833184,0.380976038,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,2288,DB00451,10017885,364,46907,87,15332,0.008362229,1.367524231,1.07872664,1.749765562,0.030842796,DB0045110017885_,3.478852058,0.313001974,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,2289,DB06643,10011906,4170,48251,874,6641,9.0452374213099e-25,0.656683598,0.607621625,0.710284792,1.35087537283597e-22,DB0664310011906_,50.35611924,-0.420552963,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,2290,DB08932,10011906,2610,16833,1316,5281,9.0275537709681e-36,0.622225663,0.578032808,0.669990475,2.92949692431971e-33,DB0893210011906_,74.91047736,-0.47445245,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,2291,DB00005,10006451,1674,126408,304,42115,4.87747691629311e-25,1.834705816,1.621769655,2.080840511,7.45374888050956e-23,DB0000510006451_,50.95074003,0.60688415,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,etanercept,DB00005
,2292,DB00005,10014011,564,127518,113,42306,3.44527996427882e-07,1.655820889,1.350302268,2.045618875,5.53202100556315e-06,DB0000510014011_,12.10495735,0.504296891,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,2293,DB00005,10022094,2476,125606,391,42028,2.06590611819864e-50,2.118952551,1.902472201,2.364914982,1.24832970843336e-47,DB0000510022094_,107.9996929,0.750921887,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,2295,DB00005,10010264,2888,125194,1000,41419,0.22259083,0.955458811,0.888042583,1.02861054,0.376710985,DB0000510010264_,0.976277004,-0.045563624,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,2297,DB00005,10016334,517,127565,130,42289,0.004683899,1.318370961,1.085373141,1.610992034,0.019406729,DB0000510016334_,3.942135435,0.276396854,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,2298,DB00005,10052904,2109,125973,770,41649,0.020012384,0.905540832,0.832805626,0.985482103,0.06179085,DB0000510052904_,2.783999976,-0.09922291,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,2299,DB00451,10021114,292,46979,90,15329,0.676741083,1.058624921,0.832500792,1.357253452,0.803963008,DB0045110021114_,0.218202021,0.056970822,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,levothyroxine,DB00451
,2300,DB00028,10000081,103,13355,32,5583,0.155473844,1.345520729,0.895976805,2.071036435,0.291454552,DB0002810000081_,1.232871196,0.296781097,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,human immunoglobulin g,DB00028
,2301,DB00047,10000081,133,9152,91,8427,0.03119269,1.345733183,1.021265571,1.779890159,0.087330228,DB0004710000081_,2.438058617,0.296938982,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,2302,DB00158,10000081,239,16576,87,8017,0.023695802,1.328673798,1.033715162,1.720930219,0.07052929,DB0015810000081_,2.651727196,0.284181301,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,2303,DB00169,10000081,584,38107,225,17950,0.010921978,1.222586823,1.045400869,1.433747283,0.03820403,DB0016910000081_,3.264814282,0.200968961,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,2304,DB00316,10000081,1159,64315,536,36417,0.000105309,1.224405042,1.10331357,1.360006828,0.000834376,DB0031610000081_,7.088825972,0.202455046,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,2305,DB00399,10000081,87,6905,38,4960,0.01049555,1.644506061,1.109032935,2.479532196,0.036995511,DB0039910000081_,3.296958696,0.497440073,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,2308,DB00836,10000081,188,5347,99,3976,0.006280518,1.412027521,1.097118647,1.826456899,0.024564155,DB0083610000081_,3.706466995,0.34502663,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,2309,DB00868,10000081,37,2947,20,1626,1,1.020729049,0.575108519,1.86264566,1,DB0086810000081_,0,0.020517126,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,benzonatate,DB00868
,2310,DB00959,10000081,147,7931,69,4933,0.056726786,1.325074949,0.986540255,1.79453916,0.137317639,DB0095910000081_,1.985458506,0.281469023,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,2311,DB01075,10000081,319,19629,134,10963,0.005653302,1.329576342,1.081745422,1.641550512,0.022576275,DB0107510000081_,3.790855686,0.284860351,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,2312,DB01306,10000081,76,4132,44,3822,0.016341344,1.597587996,1.08485433,2.37803231,0.052683949,DB0130610000081_,2.943444443,0.468494989,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,insulin aspart,DB01306
,2313,DB01377,10000081,98,3698,38,2632,0.001445927,1.835360518,1.245403313,2.753943099,0.007460972,DB0137710000081_,4.89806955,0.60724093,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,magnesium oxide,DB01377
,2314,DB01592,10000081,95,6181,42,3025,0.647029779,1.10696713,0.759981355,1.636436396,0.782313016,DB0159210000081_,0.245500343,0.10162396,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,2315,DB08895,10000081,305,27809,58,6588,0.13967919,1.24576667,0.936854053,1.681671597,0.269359864,DB0889510000081_,1.311707009,0.21975114,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,2318,DB00028,10012735,327,13131,127,5488,0.531739927,1.076114026,0.871843415,1.334808063,0.688613291,DB0002810012735_,0.373075426,0.073356428,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,human immunoglobulin g,DB00028
,2319,DB00047,10012735,428,8857,330,8188,0.015708666,1.198991532,1.032867972,1.392854797,0.051117583,DB0004710012735_,2.97362676,0.181480813,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,2320,DB00158,10012735,935,15880,414,7690,0.143196432,1.093676784,0.969930339,1.234796345,0.274328066,DB0015810012735_,1.293430569,0.089545216,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,2321,DB00316,10012735,3237,62237,1503,35450,1.03515706552395e-10,1.226697742,1.151959162,1.306798627,3.36704520583203e-09,DB0031610012735_,19.50923027,0.204325796,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,2322,DB00399,10012735,586,6406,272,4726,4.58453179361464e-10,1.589345837,1.367228749,1.850995725,1.35322198983898e-08,DB0039910012735_,18.11819234,0.463322508,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,2324,DB00698,10012735,164,2984,11,418,0.016369204,2.088129072,1.124292453,4.302060889,0.052744863,DB0069810012735_,2.942288895,0.736268484,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,nitrofurantoin,DB00698
,2325,DB00836,10012735,974,4561,538,3537,4.24213936361295e-09,1.403896765,1.250849296,1.576745989,1.03532621330145e-07,DB0083610012735_,16.08337909,0.339251774,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,2326,DB00868,10012735,178,2806,67,1579,0.005992829,1.49487179,1.114527746,2.024589467,0.023641229,DB0086810012735_,3.744763088,0.402040444,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,benzonatate,DB00868
,2327,DB00959,10012735,381,7697,192,4810,0.017575624,1.240037455,1.035810651,1.48841681,0.05586158,DB0095910012735_,2.884878429,0.215141584,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,2328,DB01075,10012735,850,19098,392,10705,0.001667246,1.215384601,1.074480082,1.376682517,0.008376866,DB0107510012735_,4.782281471,0.19506057,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,2329,DB01306,10012735,232,3976,170,3696,0.021258153,1.268560054,1.0308863,1.563542281,0.064893465,DB0130610012735_,2.735008355,0.237882442,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,insulin aspart,DB01306
,2330,DB01377,10012735,285,3511,150,2520,0.002902951,1.363648692,1.10745591,1.684366509,0.01315204,DB0137710012735_,4.331178368,0.310163969,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,magnesium oxide,DB01377
,2331,DB01592,10012735,429,5847,216,2851,0.728147693,0.968462432,0.815226378,1.152898341,0.841426135,DB0159210012735_,0.172657047,-0.032045586,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,2332,DB08895,10012735,1112,27002,223,6423,0.023065381,1.186148952,1.023603991,1.379383372,0.069063455,DB0889510012735_,2.672729563,0.170711885,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,2335,DB00028,10013709,215,13243,147,5468,5.04463503832553e-06,0.603915024,0.486156393,0.751842833,5.97154838920903e-05,DB0002810013709_,9.72591921,-0.50432178,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,2336,DB00047,10013709,379,8906,359,8159,0.678933254,0.967153175,0.832272116,1.124110898,0.805653035,DB0004710013709_,0.216102106,-0.033398393,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,2337,DB00158,10013709,1021,15794,387,7717,2.77716940929298e-05,1.289070258,1.141858647,1.457428361,0.000265158,DB0015810013709_,8.235186046,0.253921228,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,2338,DB00316,10013709,2485,62989,1216,35737,3.07502827546249e-05,1.15946329,1.080790186,1.244281563,0.000289859,DB0031610013709_,8.146116751,0.147957217,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,2339,DB00399,10013709,124,6868,75,4923,0.276846482,1.185082238,0.880425672,1.604378433,0.440319666,DB0039910013709_,0.820254302,0.169812171,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,2341,DB00698,10013709,120,3028,18,411,0.688316159,0.904885063,0.541730003,1.595809651,0.812082689,DB0069810013709_,0.20815311,-0.099947346,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,nitrofurantoin,DB00698
,2342,DB00836,10013709,150,5385,121,3954,0.454868336,0.910251749,0.708974728,1.170572304,0.622442055,DB0083610013709_,0.474104739,-0.09403407,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,2343,DB00868,10013709,62,2922,32,1614,0.827945444,1.070191043,0.684435567,1.702442642,0.909558014,DB0086810013709_,0.094796497,0.067837177,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,benzonatate,DB00868
,2344,DB00959,10013709,580,7498,345,4657,0.550933712,1.044167718,0.907641552,1.202546353,0.704994529,DB0095910013709_,0.349565236,0.043220126,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,2345,DB01075,10013709,510,19438,247,10850,0.071227189,1.152548007,0.986269055,1.349645232,0.163404465,DB0107510013709_,1.811526772,0.14197515,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,2346,DB01306,10013709,150,4058,147,3719,0.594481426,0.935197288,0.736527367,1.187510109,0.740390177,DB0130610013709_,0.300577966,-0.066997769,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,2347,DB01377,10013709,90,3706,59,2611,0.736474252,1.074714647,0.762258636,1.52483003,0.847817883,DB0137710013709_,0.165089427,0.072055182,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,2348,DB01592,10013709,224,6052,86,2981,0.056427268,1.282966098,0.992094464,1.671465014,0.13686359,DB0159210013709_,1.988770542,0.249174661,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,2349,DB08895,10013709,5421,22693,1383,5263,0.005079452,0.909082458,0.850506769,0.972069119,0.020712597,DB0889510013709_,3.877013237,-0.095319476,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,2352,DB00028,10016256,831,12627,240,5375,1.21727342033491e-07,1.473872307,1.270454119,1.714802216,2.17512113212121e-06,DB0002810016256_,13.0384262,0.38789316,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,2353,DB00047,10016256,405,8880,353,8165,0.480388634,1.054944661,0.909389642,1.224210386,0.645173606,DB0004710016256_,0.438235842,0.053488312,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,2354,DB00158,10016256,1070,15745,465,7639,0.055818501,1.116420767,0.996835309,1.2517851,0.135760943,DB0015810016256_,1.996859712,0.110127824,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,2355,DB00399,10016256,739,6253,479,4519,0.080567387,1.114927706,0.986157597,1.261402536,0.179338085,DB0039910016256_,1.718482514,0.108789565,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,2357,DB00698,10016256,205,2943,27,402,1,1.037107553,0.68143421,1.634056403,1,DB0069810016256_,0,0.03643564,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,nitrofurantoin,DB00698
,2358,DB00836,10016256,470,5065,276,3799,0.002013859,1.277224645,1.091791798,1.496279716,0.009783624,DB0083610016256_,4.627045361,0.244689477,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,2359,DB00868,10016256,230,2754,113,1533,0.319065641,1.132989947,0.892514897,1.44456825,0.487170512,DB0086810016256_,0.719141089,0.124860109,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,benzonatate,DB00868
,2360,DB00959,10016256,479,7599,232,4770,0.001491666,1.295987776,1.100844517,1.529037013,0.007654909,DB0095910016256_,4.872408077,0.259273166,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,2361,DB01075,10016256,1370,18578,617,10480,5.96879000775891e-06,1.252521854,1.134685161,1.383764163,6.89928079832643e-05,DB0107510016256_,9.581508291,0.225159002,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,2362,DB01306,10016256,227,3981,186,3680,0.24499706,1.128137125,0.920310449,1.384260421,0.403748128,DB0130610016256_,0.906964041,0.12056771,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,2363,DB01377,10016256,302,3494,171,2499,0.019830314,1.263102111,1.036039506,1.543705185,0.061347836,DB0137710016256_,2.791195385,0.233570688,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,2364,DB01592,10016256,514,5762,244,2823,0.716618298,1.032072165,0.878450599,1.214994547,0.832470586,DB0159210016256_,0.183357389,0.031568592,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,2365,DB08895,10016256,1676,26438,313,6333,6.41273737263888e-05,1.282641822,1.132485405,1.456332749,0.000544529,DB0889510016256_,7.515590248,0.248921875,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,2370,DB00158,10021519,58,16757,17,8087,0.083120577,1.646502194,0.944799426,3.018202761,0.183637266,DB0015810021519_,1.694792847,0.498653156,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,2371,DB00169,10021519,134,38557,37,18138,0.003080166,1.703670165,1.175597554,2.523959124,0.013828577,DB0016910021519_,4.281018006,0.532784844,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,2372,DB00316,10021519,108,65366,51,36902,0.321642271,1.195472863,0.849041184,1.702802438,0.489915224,DB0031610021519_,0.713522915,0.178541809,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,2383,DB08895,10021519,70,28044,17,6629,0.891711407,0.973322013,0.566285357,1.76548384,0.955005127,DB0889510021519_,0.04603857,-0.027040303,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,2406,DB00158,10061225,44,16771,10,8094,0.028747184,2.123467238,1.052223494,4.734961097,0.081923319,DB0015810061225_,2.501971607,0.753050242,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,2407,DB00169,10061225,98,38593,33,18142,0.110464196,1.396032515,0.931922948,2.139761787,0.226763484,DB0016910061225_,1.483847723,0.333634296,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,2408,DB00316,10061225,137,65337,59,36894,0.086842122,1.311191266,0.959277813,1.811371814,0.189793396,DB0031610061225_,1.661819187,0.270936087,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,2419,DB08895,10061225,86,28028,22,6624,0.713846943,0.923844031,0.572498775,1.551431446,0.83029176,DB0889510061225_,0.185978122,-0.079212019,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,2441,DB06292,10046571,72,1285,34,1199,0.00101857,1.975413679,1.28562721,3.088315437,0.005588793,DB0629210046571_,5.186991847,0.680777834,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,dapagliflozin,DB06292
,2444,DB01080,10047571,32,2027,51,2061,0.058804609,0.638046818,0.395034663,1.016835323,0.141228878,DB0108010047571_,1.957373456,-0.449343616,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,vigabatrin,DB01080
,2445,DB00005,10022067,2478,125604,875,41544,0.102235568,0.93668934,0.866138931,1.013703669,0.214340179,DB0000510022067_,1.540190903,-0.065403599,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,2446,DB00060,10028596,111,9397,59,2406,2.0644466218676e-05,0.481723675,0.346994224,0.674578135,0.000205312,DB0006010028596_,8.490979456,-0.730384617,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,interferon beta-1a,DB00060
,2448,DB00316,10028596,264,65210,313,36640,6.32686797284192e-19,0.473910221,0.40059529,0.560369635,5.91821084221173e-17,DB0031610028596_,37.3659124,-0.746737382,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,2451,DB00761,10028596,107,15200,106,8519,4.02547552638971e-05,0.565792109,0.427827429,0.748252078,0.000366694,DB0076110028596_,7.910982179,-0.569528566,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,2454,DB01136,10028596,147,9737,201,10914,0.073871902,0.819755997,0.656916237,1.021019617,0.167962624,DB0113610028596_,1.784013803,-0.198748547,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,carvedilol,DB01136
,2455,DB01224,10028596,24,8084,30,5887,0.053052147,0.582618731,0.325575392,1.032042091,0.130734138,DB0122410028596_,2.034589497,-0.540222284,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,quetiapine,DB01224
,2457,DB00060,10061822,316,9192,59,2406,0.01928987,1.401862031,1.05456381,1.890950184,0.06009605,DB0006010061822_,2.811811171,0.337801375,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,2459,DB00316,10061822,374,65100,201,36752,0.601379667,1.05045332,0.882166298,1.253741573,0.745643272,DB0031610061822_,0.29350798,0.049221805,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,2462,DB00761,10061822,105,15202,45,8580,0.125529673,1.316917584,0.919345175,1.913321789,0.249398901,DB0076110061822_,1.388701654,0.275293842,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,2463,DB00829,10061822,43,8009,22,4432,0.796851432,1.081602439,0.631921781,1.901121844,0.89005462,DB0082910061822_,0.116472448,0.078443681,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,2465,DB01136,10061822,70,9814,49,11066,0.012579549,1.610765766,1.101081146,2.372784365,0.042751946,DB0113610061822_,3.152340563,0.476709697,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,2466,DB01224,10061822,43,8065,13,5904,0.004063754,2.421239445,1.276545893,4.912485977,0.017310718,DB0122410061822_,4.05642943,0.884279577,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,2467,DB06637,10061822,45,6117,12,2007,0.643934186,1.230346284,0.638518441,2.56064178,0.780197279,DB0663710061822_,0.24820847,0.207295662,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,2478,DB14726,10013709,42,1975,32,2816,0.008609023,1.871099141,1.148811844,3.074088654,0.031591255,DB1472610013709_,3.454874947,0.626526034,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dabigatran,DB14726
,2480,DB00343,10006093,118,8618,117,4978,5.20512281961182e-05,0.582617468,0.446159091,0.76076845,0.000457002,DB0034310006093_,7.690822528,-0.540224452,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,diltiazem,DB00343
,2485,DB00177,10021097,122,4678,91,2759,0.098482925,0.79073455,0.595212135,1.0535227,0.208625377,DB0017710021097_,1.567215088,-0.234792955,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,valsartan,DB00177
,2486,DB00343,10021097,353,8383,241,4854,0.055772679,0.848138308,0.71512643,1.007163077,0.135663971,DB0034310021097_,1.997574254,-0.164711558,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,diltiazem,DB00343
,2488,DB00177,10024855,39,4761,20,2830,0.685579319,1.159113781,0.658290885,2.101954054,0.810162856,DB0017710024855_,0.210519995,0.147655731,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,valsartan,DB00177
,2489,DB00343,10024855,78,8658,41,5054,0.633852654,1.110532741,0.750175797,1.665546673,0.772335297,DB0034310024855_,0.258336501,0.104839847,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,2491,DB00177,10033295,16,4784,35,2815,6.68778195486225e-06,0.269039508,0.138773853,0.500121847,7.63301557462241e-05,DB0017710033295_,9.480442472,-1.312897041,male,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,valsartan,DB00177
,2492,DB00343,10033295,69,8667,32,5063,0.301893273,1.259619473,0.815631866,1.98299812,0.468243831,DB0034310033295_,0.758766112,0.230809669,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,2495,DB00068,10048393,175,2059,56,609,0.624862848,0.924313637,0.670532339,1.289815707,0.764509819,DB0006810048393_,0.26852041,-0.078703831,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,interferon beta-1b,DB00068
,2496,DB00060,10012601,74,9434,28,2437,0.086195632,0.682730185,0.435402268,1.098296135,0.188686421,DB0006010012601_,1.667668791,-0.381655541,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,interferon beta-1a,DB00060
,2497,DB00060,10020772,164,9344,43,2422,0.930996239,0.988591699,0.700488733,1.421745392,0.972103284,DB0006010020772_,0.028293221,-0.011473875,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,interferon beta-1a,DB00060
,2501,DB00068,10022004,202,2032,68,597,0.362011186,0.872816756,0.649350675,1.184304533,0.531735413,DB0006810022004_,0.631609256,-0.136029647,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,2505,DB01164,10033371,76,6448,57,7879,0.006446089,1.629160766,1.138548578,2.342533932,0.025068122,DB0116410033371_,3.686158263,0.488065015,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,2506,DB01164,10062070,587,5937,815,7121,0.010175502,0.863891208,0.771294336,0.967195675,0.036058384,DB0116410062070_,3.322615877,-0.146308435,NA,10062070,Peritonitis bacterial,10021881,Infections and infestations,Infec,calcium chloride,DB01164
,2507,DB00068,10008531,96,2138,34,631,0.393010711,0.833358158,0.551981185,1.284548701,0.562989075,DB0006810008531_,0.574495056,-0.182291767,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,2508,DB00068,10028334,47,2187,15,650,0.762259968,0.931275961,0.507649312,1.80535102,0.868285351,DB0006810028334_,0.141234873,-0.071199632,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1b,DB00068
,2509,DB00068,10022095,119,2115,19,646,0.006965407,1.91272936,1.161289162,3.315110336,0.026686755,DB0006810022095_,3.623587913,0.648531206,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,2510,DB00425,10022095,42,12653,13,7471,0.04925908,1.907559471,1.003698747,3.875845273,0.123606197,DB0042510022095_,2.090654599,0.645824661,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,2511,DB00788,10022095,71,9285,10,5051,5.78412127684098e-06,3.862094488,1.979726178,8.407260967,6.71238974665629e-05,DB0078810022095_,9.60897043,1.35120965,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,2512,DB00999,10022095,108,21322,22,12217,1.45873343646868e-06,2.812710097,1.76510056,4.676774004,2.00905467003297e-05,DB0099910022095_,10.81526117,1.034148466,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,2513,DB01104,10022095,90,15373,27,7259,0.037152771,1.573942887,1.012947472,2.520190198,0.09988346,DB0110410022095_,2.303751171,0.453583864,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,2514,DB00787,10012735,1234,15766,803,16445,1.8886991112065e-24,1.602884444,1.461390309,1.758775781,2.78901438977882e-22,DB0078710012735_,49.63118378,0.471804784,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,2515,DB00829,10012735,324,7728,128,4326,0.000941429,1.416911985,1.147112107,1.758517081,0.005240462,DB0082910012735_,5.2513457,0.348479845,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,diazepam,DB00829
,2520,DB00398,10042128,21,706,30,1508,0.172919752,1.494926355,0.807284201,2.721119613,0.31468797,DB0039810042128_,1.156173703,0.402076945,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,sorafenib,DB00398
,2521,DB00068,10022061,190,2044,44,621,0.123679725,1.31179328,0.92802896,1.888145254,0.246636945,DB0006810022061_,1.399837884,0.271395117,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,2522,DB00068,10022086,202,2032,56,609,0.698089969,1.081048439,0.788461714,1.501478222,0.818434203,DB0006810022086_,0.200362273,0.077931347,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,2523,DB00983,10064385,70,3431,34,1706,1,1.023707179,0.667283178,1.597640603,1,DB0098310064385_,0,0.023430528,NA,10064385,Circumstance or information capable of leading to medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,formoterol,DB00983
,2524,DB00983,10067482,654,2847,355,1385,0.136975721,0.896236323,0.774107923,1.038638875,0.265467784,DB0098310067482_,1.326261786,-0.109551147,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,formoterol,DB00983
,2525,DB00983,10069327,1003,2498,492,1248,0.795016014,1.018490834,0.894982395,1.159794047,0.88896907,DB0098310069327_,0.117692836,0.018321957,NA,10069327,Product quality issue,10077536,Product issues,Prod,formoterol,DB00983
,2526,DB00005,10020642,463,127619,138,42281,0.298389974,1.111555511,0.916912935,1.354676221,0.46438204,DB0000510020642_,0.767047704,0.105760395,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,2527,DB00005,10050858,74,128008,22,42397,0.724003537,1.114054344,0.684195894,1.88388941,0.837791459,DB0000510050858_,0.176986066,0.108005923,NA,10050858,Corrective lens user,10041244,Social circumstances,SocCi,etanercept,DB00005
,2528,DB00285,10013700,860,10091,179,3539,1.05659179822876e-10,1.68491515,1.425857156,1.999687038,3.42870560696826e-09,DB0028510013700_,19.49108302,0.521715207,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,venlafaxine,DB00285
,2529,DB00584,10013700,84,1997,35,1839,7.69815494356792e-05,2.209580264,1.464735524,3.396543462,0.000636909,DB0058410013700_,7.358883704,0.792802572,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,enalapril,DB00584
,2530,DB00635,10013700,896,32157,197,23597,1.48274656712626e-64,3.337391646,2.854539924,3.917881981,1.47071673648731e-61,DB0063510013700_,140.0719408,1.205189558,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,prednisone,DB00635
,2531,DB00843,10013700,39,2155,15,2158,0.001409203,2.603203628,1.398042106,5.098383913,0.007297262,DB0084310013700_,4.920256067,0.956742851,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,donepezil,DB00843
,2532,DB01039,10013700,132,2841,62,2989,1.10167552732349e-07,2.239664695,1.636352688,3.093312212,1.98067997508194e-06,DB0103910013700_,13.13207035,0.806326165,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,fenofibrate,DB01039
,2533,DB01067,10013700,143,4218,75,4748,6.39578810946674e-08,2.146082807,1.60644316,2.886415494,1.20857865174215e-06,DB0106710013700_,13.62606556,0.76364423,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,glipizide,DB01067
,2534,DB01098,10013700,375,7774,167,7042,1.04506462855444e-14,2.033973751,1.6854385,2.462785721,6.12099627711955e-13,DB0109810013700_,28.12188134,0.709991392,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,rosuvastatin,DB01098
,2535,DB00230,10028813,1073,18601,254,8397,7.26411054481925e-22,1.906975007,1.657532457,2.200525033,9.0922450319321e-20,DB0023010028813_,43.84428,0.645518221,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,2536,DB00285,10028813,713,10238,160,3558,4.95306266648069e-07,1.548677808,1.297030358,1.857908276,7.68770311121612e-06,DB0028510028813_,11.7758885,0.43740154,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,2537,DB00584,10028813,130,1951,74,1800,0.001160199,1.620588721,1.199737407,2.202354931,0.006230153,DB0058410028813_,5.078354461,0.482789491,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,enalapril,DB00584
,2538,DB00843,10028813,91,2103,77,2096,0.307352575,1.177838918,0.854436391,1.627124248,0.474477432,DB0084310028813_,0.745541223,0.163681334,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,donepezil,DB00843
,2539,DB01039,10028813,222,2751,138,2913,1.55383659983659e-06,1.703262494,1.361967993,2.135974288,2.12555789886572e-05,DB0103910028813_,10.75889116,0.532545526,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fenofibrate,DB01039
,2540,DB01098,10028813,529,7620,286,6923,2.7211308799899e-12,1.680399212,1.44700413,1.954564074,1.13983944510812e-10,DB0109810028813_,22.89496352,0.519031391,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,2541,DB00230,10047700,548,19126,127,8524,3.05522667462333e-12,1.923035512,1.579874386,2.355286568,1.26520347318746e-10,DB0023010047700_,22.79061797,0.653904933,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,2542,DB00285,10047700,345,10606,82,3636,0.002730754,1.442294839,1.127051186,1.863907134,0.012518707,DB0028510047700_,4.380531198,0.366235483,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,2543,DB00584,10047700,73,2008,42,1832,0.017955204,1.585565005,1.064106993,2.389257502,0.056748937,DB0058410047700_,2.869118346,0.460940814,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,enalapril,DB00584
,2544,DB00843,10047700,70,2124,57,2116,0.280530138,1.223386098,0.845330762,1.776871275,0.444377777,DB0084310047700_,0.81108023,0.201622504,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,donepezil,DB00843
,2545,DB01039,10047700,98,2875,50,3001,3.89151838169179e-05,2.045648691,1.434710594,2.948116872,0.000356344,DB0103910047700_,7.93961385,0.715714947,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,fenofibrate,DB01039
,2546,DB01067,10047700,134,4227,72,4751,4.22542266546855e-07,2.091674316,1.554303426,2.834287364,6.64067173463921e-06,DB0106710047700_,11.92229743,0.737964853,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,glipizide,DB01067
,2547,DB01098,10047700,237,7912,117,7092,1.08241923816423e-07,1.815628132,1.445294121,2.291029484,1.95072949435358e-06,DB0109810047700_,13.14730716,0.596431486,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,2549,DB00115,10001760,290,18135,33,10439,1.01635699408915e-26,5.057830905,3.518139181,7.494802721,1.77507930828127e-24,DB0011510001760_,54.68819713,1.620937716,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,2552,DB00451,10001760,771,46500,57,15362,3.98328075942803e-41,4.468663114,3.409843027,5.959709071,1.63594585564946e-38,DB0045110001760_,87.00601239,1.497089284,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,2553,DB00115,10010774,462,17963,283,10189,0.315652996,0.925997718,0.795270144,1.079689584,0.483293374,DB0011510010774_,0.727131411,-0.076883509,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,2556,DB00451,10010774,1004,46267,342,15077,0.481638247,0.956643466,0.844114221,1.086239219,0.646224617,DB0045110010774_,0.436608132,-0.044324511,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,2557,DB00115,10015967,52,18373,12,10460,0.003796289,2.466956162,1.298826761,5.079722929,0.01635291,DB0011510015967_,4.113349397,0.902985068,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,cyanocobalamin,DB00115
,2560,DB00451,10015967,140,47131,24,15395,0.002590329,1.90530161,1.229152292,3.074565996,0.011996976,DB0045110015967_,4.42310066,0.644640321,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,levothyroxine,DB00451
,2564,DB00451,10027091,48,47223,21,15398,0.264044305,0.745306602,0.437647754,1.31090401,0.425935411,DB0045110027091_,0.853467562,-0.293959598,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,2565,DB00115,10028334,404,18021,151,10321,6.28925397986987e-06,1.532290569,1.265814286,1.862754555,7.23945876334046e-05,DB0011510028334_,9.533379018,0.42676372,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,2568,DB00451,10028334,850,46421,195,15224,4.09265617393677e-06,1.429508992,1.220720078,1.680741784,4.95282999686593e-05,DB0045110028334_,9.912966335,0.357331023,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,2571,DB00451,10033775,529,46742,96,15323,1.83443012932259e-08,1.806322954,1.449677018,2.271176725,3.87293140154572e-07,DB0045110033775_,14.76408396,0.591293262,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,2572,DB00115,10047899,337,18088,125,10347,2.6078285379386e-05,1.542188733,1.250488434,1.911871912,0.000250445,DB0011510047899_,8.292271564,0.433202663,NA,10047899,Weight increased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,2575,DB00451,10047899,975,46296,213,15206,3.31635862717801e-08,1.503422867,1.293474081,1.753927931,6.63650449298622e-07,DB0045110047899_,14.22551026,0.40774442,NA,10047899,Weight increased,10022891,Investigations,Inv,levothyroxine,DB00451
,2576,DB00115,10048959,439,17986,176,10296,6.50388445478077e-05,1.427843568,1.193967693,1.713433189,0.000551289,DB0011510048959_,7.503252064,0.356165312,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,2579,DB00451,10048959,972,46299,224,15195,1.19305971389585e-06,1.424083918,1.228821731,1.656174214,1.67474363576782e-05,DB0045110048959_,10.99726536,0.353528743,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,2580,DB00108,10012601,53,10141,21,3274,0.417495213,0.814806367,0.482351293,1.424469597,0.586562773,DB0010810012601_,0.533475588,-0.20480478,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,natalizumab,DB00108
,2586,DB00559,10034474,60,9599,19,3287,0.897000735,1.081355744,0.63526885,1.921783181,0.956338178,DB0055910034474_,0.044643686,0.078215573,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,bosentan,DB00559
,2587,DB00820,10034474,103,11812,34,5782,0.054570796,1.482873039,0.996127763,2.257416181,0.133587275,DB0082010034474_,2.01300027,0.393981448,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,tadalafil,DB00820
,2590,DB00559,10064911,422,9237,157,3149,0.35451412,0.916333821,0.757585699,1.112740099,0.524363591,DB0055910064911_,0.645569959,-0.087374547,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,2591,DB00820,10064911,657,11258,199,5617,4.0254538138266e-10,1.647191561,1.398774115,1.946448661,1.202375607914e-08,DB0082010064911_,18.23638147,0.499071753,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,2592,DB06643,10013573,453,51968,99,7416,0.00028196,0.6529835,0.523527255,0.821166741,0.001920028,DB0664310013573_,6.255415731,-0.426203419,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,2593,DB06643,10016334,86,52335,6,7509,0.083729792,2.056517755,0.906702735,5.760913736,0.184649516,DB0664310016334_,1.689295757,0.721014142,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,2594,DB06643,10024264,66,52355,10,7505,0.861989205,0.946086346,0.48318617,2.064929743,0.935727247,DB0664310024264_,0.066431247,-0.05542144,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,2595,DB06643,10025482,512,51909,64,7451,0.342620886,1.148354101,0.883099433,1.515166616,0.511943097,DB0664310025482_,0.669541799,0.1383297,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,2596,DB06643,10028813,692,51729,135,7380,0.001475602,0.73130442,0.606303761,0.8875049,0.007586037,DB0664310028813_,4.881446002,-0.312925462,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,2599,DB08895,10001760,679,27435,35,6611,4.34197723958285e-29,4.67471028,3.32369954,6.774557859,9.05784696368533e-27,DB0889510001760_,59.96616606,1.542167189,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,2602,DB01229,10037377,112,5629,59,2650,0.508037943,0.893694116,0.64399203,1.251059211,0.668691904,DB0122910037377_,0.402431856,-0.112391714,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,paclitaxel,DB01229
,2603,DB01234,10037377,361,31264,482,32406,0.000306142,0.776325378,0.67482401,0.892466398,0.00205148,DB0123410037377_,6.189193713,-0.253183545,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,2605,DB00349,10013709,102,920,78,866,0.210428903,1.230804596,0.893764052,1.700076624,0.361712305,DB0034910013709_,1.016906121,0.207668099,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,clobazam,DB00349
,2606,DB00776,10013709,162,1743,159,1180,0.001866579,0.689864332,0.543834141,0.875123,0.009196442,DB0077610013709_,4.688938624,-0.371260321,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,oxcarbazepine,DB00776
,2608,DB01104,10013709,808,14655,367,6919,0.563452972,1.039447951,0.91453942,1.183100438,0.715372717,DB0110410013709_,0.334951589,0.038689756,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,2610,DB00349,10013752,53,969,54,890,0.619939322,0.901512041,0.598354757,1.35778238,0.760529501,DB0034910013752_,0.273740377,-0.103681879,NA,10013752,Drug withdrawal convulsions,10029205,Nervous system disorders,Nerv,clobazam,DB00349
,2613,DB01080,10013752,106,1953,101,2011,0.617909784,1.080630182,0.808973842,1.444282845,0.758853874,DB0108010013752_,0.275946044,0.077544373,NA,10013752,Drug withdrawal convulsions,10029205,Nervous system disorders,Nerv,vigabatrin,DB01080
,2620,DB01104,10018100,42,15421,18,7268,0.783536762,1.099705302,0.61895924,2.031129339,0.882171087,DB0110410018100_,0.125369266,0.095042237,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,2627,DB00005,10011781,433,127649,26,42393,1.17970992791104e-27,5.53087817,3.722270255,8.566629159,2.23889353466728e-25,DB0000510011781_,56.75864554,1.710346604,female,10011781,Cystitis,10021881,Infections and infestations,Infec,etanercept,DB00005
,2628,DB00072,10002034,109,3614,14,321,0.185591782,0.691613581,0.3893061,1.322386461,0.330910323,DB0007210002034_,1.105907867,-0.368727888,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,trastuzumab,DB00072
,2629,DB00997,10002034,226,5105,118,3396,0.037544606,1.274050288,1.010798784,1.612538148,0.100658912,DB0099710002034_,2.296017588,0.242201029,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,doxorubicin,DB00997
,2631,DB00072,10012735,454,3269,28,307,0.042049222,1.522579175,1.01776502,2.35878364,0.109796236,DB0007210012735_,2.209129029,0.420405723,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,trastuzumab,DB00072
,2632,DB00531,10012735,304,6948,224,6292,0.023338166,1.228987374,1.02718021,1.47218062,0.069654105,DB0053110012735_,2.664213638,0.206190557,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,2633,DB00997,10012735,206,5125,110,3404,0.069794335,1.243823763,0.977873776,1.588983933,0.160946097,DB0099710012735_,1.826685769,0.218190315,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,doxorubicin,DB00997
,2634,DB01229,10012735,353,5388,114,2595,0.000233075,1.491284204,1.197496429,1.868261844,0.001637191,DB0122910012735_,6.414773587,0.399637631,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,paclitaxel,DB01229
,2635,DB01234,10012735,2242,29383,1465,31423,4.61030782293257e-47,1.636597651,1.528646307,1.752524499,2.49859672424294e-44,DB0123410012735_,100.3980148,0.492619484,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,2643,DB00072,10016256,345,3378,26,309,0.428041557,1.213738162,0.79804554,1.916672118,0.596541572,DB0007210016256_,0.516606346,0.193704988,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,trastuzumab,DB00072
,2644,DB00531,10016256,409,6843,271,6245,6.75518276804741e-05,1.377299952,1.173793325,1.618123035,0.000569559,DB0053110016256_,7.470648402,0.320125026,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,2645,DB00997,10016256,347,4984,123,3391,3.20936943230078e-10,1.919295429,1.550490796,2.388518914,9.71310023350903e-09,DB0099710016256_,18.44979032,0.651958155,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,2646,DB01229,10016256,498,5243,152,2557,4.62406784226182e-07,1.59776974,1.321218055,1.940796753,7.22932493339722e-06,DB0122910016256_,11.8373649,0.468608744,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,2649,DB00997,10019211,100,5231,49,3465,0.091397557,1.351785884,0.948393626,1.949001649,0.197506266,DB0099710019211_,1.621984966,0.301426595,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,doxorubicin,DB00997
,2652,DB00531,10020635,30,7222,40,6476,0.118296043,0.672553281,0.403978363,1.108647848,0.238671438,DB0053110020635_,1.43266741,-0.396673942,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,cyclophosphamide,DB00531
,2654,DB01229,10020635,40,5701,22,2687,0.585597203,0.856973556,0.496079503,1.517153876,0.733042313,DB0122910020635_,0.310551854,-0.154348217,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,paclitaxel,DB01229
,2655,DB01234,10020635,119,31506,149,32739,0.141637684,0.829916927,0.64629233,1.063756888,0.272065662,DB0123410020635_,1.301711836,-0.186429672,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,2657,DB00072,10028813,320,3403,20,315,0.100049967,1.480918893,0.926231661,2.49357351,0.210848939,DB0007210028813_,1.556613331,0.392662769,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,trastuzumab,DB00072
,2658,DB00997,10028813,394,4937,150,3364,1.14331479406526e-09,1.789653421,1.471272707,2.185886373,3.13859314485694e-08,DB0099710028813_,17.27690609,0.582021981,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,doxorubicin,DB00997
,2661,DB00997,10029354,315,5016,209,3305,0.963298908,0.993066038,0.826384094,1.195245166,1,DB0099710029354_,0,-0.006958113,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,doxorubicin,DB00997
,2663,DB00005,10042609,1119,126963,386,42033,0.491001371,0.959742809,0.853659682,1.080806967,0.654195868,DB0000510042609_,0.42434848,-0.041089937,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,2668,DB00480,10000880,74,67354,101,67561,0.04896824,0.73492936,0.53689774,1.002049855,0.12305848,DB0048010000880_,2.095095586,-0.307980893,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,2670,DB00480,10016288,186,67242,250,67412,0.002488309,0.745885131,0.613410144,0.905655834,0.011622414,DB0048010016288_,4.454819835,-0.293183671,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,lenalidomide,DB00480
,2671,DB00480,10040047,557,66871,703,66959,5.08892793640728e-05,0.793364484,0.708226848,0.888398512,0.000448792,DB0048010040047_,7.708950916,-0.231472536,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,2672,DB00480,10043554,425,67003,602,67060,3.95356762450143e-08,0.706585632,0.622292645,0.801722001,7.79299025197002e-07,DB0048010043554_,14.06487101,-0.347310878,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,lenalidomide,DB00480
,2673,DB00480,10003983,150,67278,218,67444,0.00045762,0.689776295,0.556326949,0.853367112,0.002868036,DB0048010003983_,5.854127903,-0.371387944,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,2674,DB00480,10007739,495,66933,395,67267,0.000674725,1.259412852,1.100682987,1.441779142,0.003973373,DB0048010007739_,5.528140045,0.230645622,NA,10007739,Cataract,10015919,Eye disorders,Eye,lenalidomide,DB00480
,2675,DB00451,10033557,531,46740,52,15367,2.27333695168042e-22,3.357386888,2.520451428,4.556388931,2.96549189949974e-20,DB0045110033557_,44.96465894,1.21116296,female,10033557,Palpitations,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,2676,DB00451,10044565,577,46694,138,15281,0.000763966,1.36829203,1.133426667,1.661350083,0.0044008,DB0045110044565_,5.42596892,0.313563269,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,2677,DB00451,10047700,1517,45754,349,15070,7.68045637519272e-10,1.431630048,1.271633157,1.615331566,2.18131600023707e-08,DB0045110047700_,17.64075238,0.358813689,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,2678,DB06403,10011906,1562,19909,703,5958,6.86578828531001e-17,0.664942033,0.605037848,0.731256321,5.20078516078887e-15,DB0640310011906_,32.88996679,-0.408055411,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,2679,DB00115,10012378,391,18034,126,10346,6.62846438862959e-09,1.780238882,1.450507135,2.196911153,1.54732847651091e-07,DB0011510012378_,15.68156577,0.576747559,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,2680,DB00169,10012378,794,37897,242,17933,8.42495350403963e-10,1.552566155,1.341241019,1.802375499,2.37607191903092e-08,DB0016910012378_,17.55523207,0.439909146,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,2681,DB00316,10012378,1079,64395,398,36555,6.33247491449724e-14,1.538973478,1.369572216,1.73205144,3.3289820625512e-12,DB0031610012378_,26.42835455,0.431115622,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,2682,DB00480,10012378,236,67192,227,67435,0.67528538,1.043420551,0.865616685,1.257895342,0.803143649,DB0048010012378_,0.219221691,0.042504308,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,2684,DB00695,10012378,339,27710,144,20384,1.79924061828332e-08,1.731743782,1.419604852,2.121305217,3.80781317645547e-07,DB0069510012378_,14.7810406,0.549128867,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,2685,DB00761,10012378,205,15102,77,8548,0.00217717,1.506905725,1.152491,1.987374917,0.010432395,DB0076110012378_,4.562839445,0.41005836,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,potassium chloride,DB00761
,2686,DB11089,10012378,150,10025,86,8321,0.006859511,1.447686683,1.101373011,1.912982948,0.026385051,DB1108910012378_,3.634957663,0.369966892,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,docusate,DB11089
,2687,DB14513,10012378,130,7047,40,3524,0.006641266,1.625163199,1.129430911,2.383939581,0.025695985,DB1451310012378_,3.661420508,0.485608241,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,magnesium,DB14513
,2688,DB00115,10015090,127,18298,51,10421,0.034794281,1.418189527,1.0161604,2.005087218,0.09503612,DB0011510015090_,2.353498247,0.349381077,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,2689,DB00169,10015090,229,38462,120,18055,0.328222832,0.895824673,0.714616787,1.127639293,0.496823331,DB0016910015090_,0.699520786,-0.110010563,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,2690,DB00480,10015090,197,67231,210,67452,0.551661377,0.94115626,0.770708501,1.149012011,0.705616511,DB0048010015090_,0.348683375,-0.060646096,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,2692,DB00695,10015090,297,27752,186,20342,0.095758364,1.170400743,0.970234562,1.414817717,0.204418793,DB0069510015090_,1.587584481,0.157346206,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,2693,DB00761,10015090,153,15154,89,8536,0.840071046,0.968317805,0.739801469,1.273863559,0.918178197,DB0076110015090_,0.085363793,-0.032194935,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,2694,DB11089,10015090,72,10103,45,8362,0.162025806,1.324258408,0.898927074,1.969263964,0.300066816,DB1108910015090_,1.203750108,0.280852611,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,2695,DB14513,10015090,46,7131,15,3549,0.173537247,1.526181953,0.835399553,2.947266073,0.315509405,DB1451310015090_,1.153566789,0.422769161,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium,DB14513
,2696,DB00115,10016173,753,17672,396,10076,0.210346248,1.084189843,0.956279832,1.230622014,0.361605699,DB0011510016173_,1.017200889,0.08083302,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,2697,DB00169,10016173,1503,37188,657,17518,0.120546645,1.077640895,0.980818307,1.18496135,0.24216199,DB0016910016173_,1.418148397,0.074774295,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,2698,DB00316,10016173,1892,63582,972,35981,0.016049718,1.101536558,1.017866378,1.192603458,0.051944447,DB0031610016173_,2.957580452,0.096706076,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,2699,DB00480,10016173,1720,65708,1408,66254,9.51988996477086e-09,1.231737298,1.146294522,1.323700199,2.15251877612045e-07,DB0048010016173_,15.35145697,0.20842561,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,2700,DB00524,10016173,86,1491,62,1282,0.311060598,1.192588998,0.842647346,1.695865926,0.478561769,DB0052410016173_,0.736969988,0.176126572,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,metolazone,DB00524
,2701,DB00695,10016173,1127,26922,763,19765,0.091763945,1.084418582,0.986461903,1.19251605,0.198075881,DB0069510016173_,1.619105084,0.081043974,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,2702,DB00761,10016173,616,14691,321,8304,0.252199297,1.084711925,0.943640149,1.248670609,0.412318987,DB0076110016173_,0.88595799,0.081314445,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,2703,DB11089,10016173,360,9815,327,8080,0.211478297,0.906313442,0.77579144,1.05907749,0.363148039,DB1108910016173_,1.012944707,-0.09837007,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,2704,DB14513,10016173,246,6931,93,3471,0.022261373,1.324666078,1.035515944,1.706300437,0.067217791,DB1451310016173_,2.699817321,0.281160411,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium,DB14513
,2706,DB00169,10019022,58,38633,23,18152,0.551953597,1.184840354,0.719342819,2.013393334,0.705801382,DB0016910019022_,0.34842141,0.169608043,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,2707,DB00316,10019022,89,65385,56,36897,0.54500645,0.896843597,0.634716373,1.276587952,0.699866541,DB0031610019022_,0.356865617,-0.108873795,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,2708,DB00480,10019022,77,67351,52,67610,0.027630792,1.486451483,1.031967214,2.156105992,0.079416492,DB0048010019022_,2.533049231,0.396391724,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,2710,DB00695,10019022,56,27993,29,20499,0.152787059,1.414066451,0.887370236,2.29778245,0.2878446,DB0069510019022_,1.245334528,0.346469561,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,2711,DB00761,10019022,42,15265,15,8610,0.131276906,1.579270504,0.85742557,3.06775877,0.257585359,DB0076110019022_,1.356404124,0.456963034,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,2714,DB00115,10028813,1229,17196,379,10093,4.07493499300921e-29,1.903249002,1.690338388,2.146865871,8.53463476424281e-27,DB0011510028813_,60.02566495,0.643562427,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,2715,DB00169,10028813,2488,36203,620,17555,3.53901248651949e-53,1.945853368,1.77786935,2.132144536,2.32557358020412e-50,DB0016910028813_,114.2852879,0.66570063,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,2716,DB00480,10028813,2009,65419,1157,66505,3.18256063257433e-54,1.765192166,1.639863945,1.900783026,2.29187962266346e-51,DB0048010028813_,116.6024675,0.56825956,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,2717,DB00524,10028813,146,1431,62,1282,1.08870720521357e-06,2.109124511,1.540744357,2.915049942,1.54184638410768e-05,DB0052410028813_,11.07994482,0.746272938,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,metolazone,DB00524
,2718,DB00695,10028813,1879,26170,720,19808,3.80604444753562e-56,1.975238623,1.807991687,2.159709779,2.89976458850648e-53,DB0069510028813_,120.9723804,0.680689213,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,2719,DB00761,10028813,1062,14245,326,8299,4.54500361654953e-25,1.897835597,1.669699846,2.16175611,6.96591370618102e-23,DB0076110028813_,51.01842835,0.640714077,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,2720,DB11089,10028813,731,9444,353,8054,2.6982936287126e-18,1.76597164,1.547645178,2.017993917,2.38803528722932e-16,DB1108910028813_,35.97089052,0.568701043,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,2721,DB14513,10028813,522,6655,123,3441,2.94818418933992e-16,2.194186936,1.79129581,2.704459709,2.0972400924709e-14,DB1451310028813_,31.49556906,0.785811561,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,2722,DB00316,10033371,2910,62564,1077,35876,2.55121705896729e-35,1.549368785,1.442514777,1.665120792,7.84312753157372e-33,DB0031610033371_,73.92567039,0.437847613,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,2723,DB00480,10033371,959,66469,747,66915,1.78250078928768e-07,1.292409819,1.172571493,1.424910753,3.06128933331766e-06,DB0048010033371_,12.69667438,0.256508552,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,2724,DB00524,10033371,79,1498,33,1311,0.00031966,2.094523587,1.368483522,3.270165309,0.002125006,DB0052410033371_,6.153980767,0.739326123,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,2725,DB00695,10033371,1063,26986,437,20091,1.66219560113907e-26,1.810951761,1.616050898,2.032032874,2.86497123776659e-24,DB0069510033371_,54.20948392,0.593852542,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,2726,DB00761,10033371,567,14740,205,8420,1.25026331905187e-08,1.579922602,1.341175264,1.866959152,2.75351247099106e-07,DB0076110033371_,15.10521829,0.45737586,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,2727,DB11089,10033371,399,9776,219,8188,6.09960505071456e-07,1.525929815,1.287303258,1.812520002,9.23283148620974e-06,DB1108910033371_,11.59274479,0.422603939,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,2728,DB14513,10033371,328,6849,89,3475,7.18913277251242e-08,1.869771867,1.469399043,2.399493779,1.3425673529342e-06,DB1451310033371_,13.52092684,0.625816427,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,2729,DB00115,10033425,573,17852,193,10279,4.63262192254586e-11,1.709438491,1.446906504,2.02662524,1.5990606334093e-09,DB0011510033425_,20.25384948,0.536164949,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,2730,DB00169,10033425,1232,37459,286,17889,3.61636830547446e-31,2.057167033,1.805043119,2.350733633,8.7207560467336e-29,DB0016910033425_,64.60926176,0.72132981,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,2731,DB00480,10033425,783,66645,594,67068,2.20947158221903e-07,1.326541083,1.190168786,1.47919824,3.70973877602218e-06,DB0048010033425_,12.50454909,0.282574865,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,2732,DB00524,10033425,60,1517,30,1314,0.017660936,1.732046914,1.092093722,2.799565699,0.056048018,DB0052410033425_,2.881546492,0.549303897,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,metolazone,DB00524
,2733,DB00695,10033425,860,27189,388,20140,2.56837477584032e-16,1.641829198,1.452592722,1.858257258,1.8369994825296e-14,DB0069510033425_,31.62805778,0.495810985,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,2734,DB00761,10033425,409,14898,173,8452,0.001210169,1.34123099,1.117738682,1.61487165,0.006446305,DB0076110033425_,5.044248244,0.293587841,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,2735,DB11089,10033425,239,9936,132,8275,0.000144952,1.507891009,1.211556501,1.883336939,0.001095478,DB1108910033425_,6.816564738,0.410711992,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,2736,DB14513,10033425,225,6952,49,3515,1.1903926877449e-08,2.321522053,1.692950303,3.239175622,2.63268588955615e-07,DB1451310033425_,15.15009108,0.842223028,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,2737,DB00115,10042458,92,18333,25,10447,0.000679093,2.096985775,1.334540728,3.408568029,0.00399194,DB0011510042458_,5.523478039,0.740500968,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,2738,DB00169,10042458,143,38548,49,18126,0.062495683,1.372300748,0.98511819,1.940117117,0.148094061,DB0016910042458_,1.90990766,0.316488709,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,2739,DB00316,10042458,309,65165,149,36804,0.118705054,1.171234963,0.959806151,1.434475997,0.239276254,DB0031610042458_,1.430136519,0.158058716,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,2742,DB00695,10042458,44,28005,26,20502,0.399978386,1.238904695,0.74587903,2.096649313,0.569864593,DB0069510042458_,0.562356503,0.214227679,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,2743,DB00761,10042458,35,15272,18,8607,0.886251936,1.095857421,0.603623048,2.056672554,0.952702357,DB0076110042458_,0.048452746,0.09153709,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,potassium chloride,DB00761
,2744,DB11089,10042458,37,10138,32,8375,0.903756757,0.955158051,0.578380228,1.585331393,0.957417047,DB1108910042458_,0.043516196,-0.045878453,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,docusate,DB11089
,2746,DB00115,10061011,35,18390,17,10455,0.666236215,1.170444989,0.63804139,2.229109158,0.797015242,DB0011510061011_,0.226881476,0.157384009,NA,10061011,Bladder disorder,10038359,Renal and urinary disorders,Renal,cyanocobalamin,DB00115
,2747,DB00169,10061011,51,38640,24,18151,1,0.998211079,0.60299662,1.696204593,1,DB0016910061011_,0,-0.001790523,NA,10061011,Bladder disorder,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,2748,DB00316,10061011,37,65437,16,36937,0.395181679,1.305336278,0.708360558,2.513490621,0.564978732,DB0031610061011_,0.570967192,0.266460692,NA,10061011,Bladder disorder,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,2749,DB00480,10061011,50,67378,42,67620,0.406015032,1.194748849,0.776687047,1.845916473,0.575594904,DB0048010061011_,0.552351157,0.177935995,NA,10061011,Bladder disorder,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,2765,DB00169,10063541,31,38660,24,18151,0.081313069,0.606440309,0.344394649,1.080201502,0.180566878,DB0016910063541_,1.711654054,-0.500148974,NA,10063541,Bowel movement irregularity,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,2766,DB00316,10063541,32,65442,22,36931,0.480996369,0.820858545,0.462300687,1.482959261,0.64564165,DB0031610063541_,0.43751065,-0.19740448,NA,10063541,Bowel movement irregularity,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,2767,DB00480,10063541,31,67397,32,67630,1,0.972093678,0.573619853,1.645364869,1,DB0048010063541_,0,-0.028303103,NA,10063541,Bowel movement irregularity,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,2774,DB00169,10072005,39,38652,11,18164,0.171138775,1.666126121,0.836599959,3.607877941,0.312398535,DB0016910072005_,1.16347555,0.510501244,NA,10072005,Spinal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,2775,DB00316,10072005,57,65417,30,36923,0.823639805,1.072413602,0.677529831,1.729021082,0.906495228,DB0031610072005_,0.098169513,0.069911811,NA,10072005,Spinal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,2784,DB00367,10002855,741,22059,6,461,0.011509506,2.580894537,1.171020175,7.092810306,0.039850801,DB0036710002855_,3.222612774,0.948136059,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,levonorgestrel,DB00367
,2786,DB00367,10013709,1531,21269,14,453,0.000665324,2.32909469,1.369333747,4.305494234,0.0039303,DB0036710013709_,5.539039597,0.845479647,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,levonorgestrel,DB00367
,2788,DB00367,10033371,1385,21415,7,460,2.57937631103972e-06,4.249876437,2.040361605,10.65336459,3.31049347342183e-05,DB0036710033371_,10.3158282,1.446889909,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,levonorgestrel,DB00367
,2794,DB00374,10007882,187,17529,49,5675,0.19632514,1.235515199,0.896373401,1.731359455,0.344578412,DB0037410007882_,1.065433602,0.211488049,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,treprostinil,DB00374
,2797,DB01240,10003445,151,5600,65,1511,0.003121439,0.626861346,0.462921583,0.85673427,0.013976156,DB0124010003445_,4.270402516,-0.467029901,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,2798,DB09140,10003445,47,3694,20,1778,0.69556849,1.131073342,0.654988565,2.021628624,0.816771327,DB0914010003445_,0.202396117,0.123167042,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,oxygen,DB09140
,2799,DB01240,10008469,173,5578,28,1548,0.006855024,1.714512985,1.140258307,2.666520369,0.026369723,DB0124010008469_,3.635538775,0.539129066,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,2800,DB09140,10008469,122,3619,31,1767,0.000837464,1.9213253,1.280423009,2.961847968,0.004754887,DB0914010008469_,5.348582335,0.653015208,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,2801,DB01240,10010774,154,5597,40,1536,0.859390727,1.056525202,0.738140003,1.543245734,0.933395696,DB0124010010774_,0.068926056,0.054985412,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,2802,DB09140,10010774,119,3622,36,1762,0.011672055,1.60793245,1.093907951,2.414816535,0.040275759,DB0914010010774_,3.212005493,0.474949161,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,oxygen,DB09140
,2803,DB09140,10013968,1162,2579,449,1349,2.87668238951778e-06,1.353617969,1.189905252,1.541252693,3.65459625947195e-05,DB0914010013968_,10.21693984,0.302780985,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,2804,DB01240,10013971,638,5113,146,1430,0.038439149,1.222116629,1.009310895,1.487178538,0.102518699,DB0124010013971_,2.277710066,0.200584298,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,2805,DB09140,10013971,275,3466,82,1716,5.31062062799617e-05,1.660240294,1.28353584,2.166280803,0.000464989,DB0914010013971_,7.673497056,0.506962347,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,2806,DB01240,10016256,677,5074,139,1437,0.000817135,1.379266905,1.136360107,1.68327172,0.004659293,DB0124010016256_,5.368891477,0.32155213,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,2807,DB09140,10016256,496,3245,155,1643,3.51114070607034e-07,1.620082651,1.336395527,1.972116871,5.63089282849657e-06,DB0914010016256_,12.08724254,0.482477167,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,2808,DB01240,10016766,43,5708,10,1566,0.73881599,1.17968551,0.582048294,2.638914363,0.849736707,DB0124010016766_,0.162828734,0.165247886,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,2810,DB01240,10016807,551,5200,174,1402,0.086663379,0.853830038,0.711163828,1.028727716,0.189497289,DB0124010016807_,1.663380561,-0.158023123,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,epoprostenol,DB01240
,2811,DB09140,10016807,277,3464,94,1704,0.002313944,1.44949323,1.134411087,1.865279129,0.010953002,DB0914010016807_,4.514141715,0.371213999,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,oxygen,DB09140
,2814,DB01240,10028411,213,5538,49,1527,0.283994672,1.198555492,0.870007034,1.679146387,0.448511427,DB0124010028411_,0.801821119,0.181117075,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,epoprostenol,DB01240
,2815,DB09140,10028411,103,3638,37,1761,0.143216131,1.347465078,0.912829418,2.027569444,0.274335812,DB0914010028411_,1.293402333,0.298225107,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,oxygen,DB09140
,2816,DB01240,10033425,480,5271,145,1431,0.285257628,0.898711072,0.737743932,1.099803997,0.449843818,DB0124010033425_,0.798854828,-0.106793684,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,epoprostenol,DB01240
,2817,DB09140,10033425,209,3532,63,1735,0.000683357,1.629481061,1.216149792,2.208644918,0.004011621,DB0914010033425_,5.518559938,0.488261596,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,oxygen,DB09140
,2820,DB00682,10019303,246,19213,102,16262,4.96810058838441e-10,2.04125122,1.612500031,2.599806959,1.4586093978209e-08,DB0068210019303_,18.04319723,0.713562963,NA,10019303,Heart rate increased,10022891,Investigations,Inv,warfarin,DB00682
,2821,DB06403,10019303,260,21211,57,6604,0.016591984,1.420144507,1.061068355,1.929140293,0.05333174,DB0640310019303_,2.93122362,0.350758632,NA,10019303,Heart rate increased,10022891,Investigations,Inv,ambrisentan,DB06403
,2822,DB00682,10038669,33,19426,22,16342,0.419473004,1.261856123,0.71359054,2.272826753,0.588423413,DB0068210038669_,0.5303085,0.23258375,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,2843,DB00213,10010264,406,18489,181,13240,8.97899380173525e-08,1.606256666,1.342886367,1.927299967,1.64011710964983e-06,DB0021310010264_,13.32074291,0.47390642,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,2844,DB00421,10010264,320,8583,111,5141,4.75847708815692e-07,1.726710225,1.383116497,2.168820498,7.4251451624936e-06,DB0042110010264_,11.81063832,0.546217994,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,2845,DB00588,10010264,333,16191,125,8343,0.002362291,1.372706055,1.11233657,1.702803882,0.011143425,DB0058810010264_,4.496905653,0.316784015,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,2846,DB00695,10010264,717,27332,335,20193,2.602298592757e-12,1.581244994,1.385132143,1.807994105,1.09442269616988e-10,DB0069510010264_,22.93562392,0.458212507,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,2847,DB00811,10010264,16,2782,34,4122,0.250334668,0.697290593,0.358665243,1.301118465,0.410086024,DB0081110010264_,0.891388328,-0.360553036,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,2850,DB08934,10010264,29,4460,37,6167,0.802750173,1.083756727,0.64181757,1.814026858,0.893313651,DB0893410010264_,0.112817527,0.080433456,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,2851,DB00213,10053762,396,18499,278,13143,0.905695378,1.012037685,0.864480841,1.186048867,0.957861963,DB0021310053762_,0.0430516,0.011965808,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,2852,DB00421,10053762,274,8629,137,5115,0.119974517,1.185565755,0.95925671,1.470603163,0.24135391,DB0042110053762_,1.421490916,0.170220091,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,spironolactone,DB00421
,2853,DB00588,10053762,401,16123,195,8273,0.569181426,1.055182001,0.88509901,1.261308975,0.720158549,DB0058810053762_,0.328283885,0.053713264,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,2854,DB00695,10053762,567,27482,484,20044,0.012613789,0.854430331,0.754460328,0.967965098,0.042847436,DB0069510053762_,3.150109484,-0.157320311,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,2855,DB00811,10053762,38,2760,55,4101,0.915491291,1.026609674,0.658575553,1.585511024,0.962143444,DB0081110053762_,0.03859173,0.026261794,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ribavirin,DB00811
,2857,DB00213,10066901,31,18864,21,13400,0.889203056,1.048613483,0.583315185,1.920910614,0.953968782,DB0021310066901_,0.047124331,0.047468799,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,2860,DB00695,10066901,37,28012,34,20494,0.338991535,0.796178998,0.485966332,1.308063113,0.508057234,DB0069510066901_,0.677161171,-0.227931247,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,2861,DB00811,10066901,31,2767,148,4008,3.6679784237549e-11,0.303449401,0.19844825,0.450842708,1.28662972396154e-09,DB0081110066901_,20.47123965,-1.192540402,male,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,2864,DB08934,10066901,58,4431,198,6006,5.79290603520536e-11,0.397087873,0.290304033,0.536061293,1.96472948561771e-09,DB0893410066901_,20.04791127,-0.92359768,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,2870,DB00404,10046543,58,19834,23,9839,0.409024725,1.250906264,0.759222759,2.126281978,0.578411024,DB0040410046543_,0.547470549,0.2238683,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,alprazolam,DB00404
,2874,DB00497,10046543,36,19231,27,16348,0.704675953,1.133430505,0.668878843,1.942071282,0.822904333,DB0049710046543_,0.194915327,0.125248879,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,oxycodone,DB00497
,2876,DB00635,10046543,51,33002,35,23759,0.912995165,1.04904104,0.668835159,1.662635801,0.961085319,DB0063510046543_,0.039692092,0.047876451,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,2878,DB00706,10046543,7,1068,56,15869,0.117923215,1.857143798,0.71232939,4.098155931,0.238056273,DB0070610046543_,1.435248193,0.619039715,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,tamsulosin,DB00706
,2883,DB00996,10046543,123,38830,54,22371,0.100875994,1.312282943,0.945111256,1.843086839,0.212126425,DB0099610046543_,1.550572836,0.271768325,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,2890,DB00108,10016256,388,9806,94,3201,0.00955695,1.347351912,1.06886534,1.712529853,0.034345697,DB0010810016256_,3.371278527,0.298141119,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,2892,DB00108,10025482,480,9714,123,3172,0.017532214,1.274261771,1.038730768,1.572788886,0.055740458,DB0010810025482_,2.887049047,0.242367008,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,2893,DB00108,10033371,237,9957,54,3241,0.018843822,1.428515542,1.055967537,1.962524583,0.058972479,DB0010810033371_,2.830684404,0.356635822,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,2894,DB00108,10048393,948,9246,265,3030,0.029829804,1.172312538,1.015491854,1.356743622,0.084341031,DB0010810048393_,2.472886807,0.158978326,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,2897,DB00374,10010264,604,17112,215,5509,0.214392665,0.904413715,0.770390316,1.064895974,0.366749208,DB0037410010264_,1.003077021,-0.100468374,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,2898,DB06403,10010264,383,21088,144,6517,0.049328313,0.821947333,0.675441881,1.004676131,0.123756297,DB0640310010264_,2.089440997,-0.196078958,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,2899,DB00374,10013573,1454,16262,375,5349,3.9159219227557e-05,1.275321977,1.132808544,1.438477669,0.000358267,DB0037410013573_,7.934233024,0.243198678,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,2900,DB06403,10013573,1352,20119,362,6299,0.009872212,1.16930892,1.036790038,1.321307883,0.03519955,DB0640310013573_,3.346721975,0.156412907,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,2901,DB00374,10022611,57,17659,11,5713,0.121423646,1.676318592,0.869355826,3.548063024,0.243477174,DB0037410022611_,1.412732081,0.516600075,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,2902,DB06403,10022611,34,21437,18,6643,0.07207897,0.585351252,0.321175427,1.101670556,0.164912366,DB0640310022611_,1.802341062,-0.535543181,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,2903,DB00374,10042772,620,17096,198,5526,0.901180136,1.012147345,0.858528173,1.197344517,0.956927891,DB0037410042772_,0.044027239,0.012074158,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,2904,DB00374,10049414,149,17567,54,5670,0.460898691,0.890580773,0.647243232,1.241424736,0.628242907,DB0037410049414_,0.464828392,-0.115881475,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,2905,DB06403,10049414,105,21366,42,6619,0.172944815,0.774485776,0.536056093,1.137007257,0.314719516,DB0640310049414_,1.156073463,-0.255555984,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,2906,DB00374,10064911,1141,16575,366,5358,0.925925316,1.007753036,0.891330081,1.14136417,0.968423967,DB0037410064911_,0.032085305,0.007723135,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,2907,DB06403,10064911,619,20852,188,6473,0.833634605,1.022100257,0.864621713,1.212714531,0.913612642,DB0640310064911_,0.090348603,0.021859586,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,2909,DB00682,10011906,1291,18168,959,15405,0.00274115,1.141459314,1.046241871,1.245708881,0.012561214,DB0068210011906_,4.377141445,0.132307544,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,2910,DB00374,10022086,139,17577,29,5695,0.030346635,1.552909934,1.033689727,2.406942431,0.085430148,DB0037410022086_,2.460056218,0.440130548,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,2913,DB00060,10046735,57,9451,13,2452,0.767940299,1.137547224,0.613995352,2.269101616,0.872651885,DB0006010046735_,0.13621856,0.128874387,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,interferon beta-1a,DB00060
,2914,DB05259,10046735,358,10912,59,2669,0.004662372,1.484088733,1.120193622,1.995970603,0.019325151,DB0525910046735_,3.946347864,0.394800936,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,glatiramer,DB05259
,2915,DB00060,10048393,783,8725,196,2269,0.680033829,1.038921343,0.880960547,1.229557578,0.806455783,DB0006010048393_,0.215106209,0.038183005,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,2916,DB05259,10048393,782,10488,171,2557,0.219479374,1.11492355,0.938167511,1.330842619,0.372850897,DB0525910048393_,0.98657668,0.108785838,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,2917,DB00425,10013709,701,11994,304,7180,3.65462922008162e-06,1.380377778,1.200875166,1.58959191,4.49097377512133e-05,DB0042510013709_,10.01085591,0.322357214,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,2918,DB00433,10013709,137,7519,106,5914,0.948038077,1.016566757,0.781255062,1.325744047,0.986490909,DB0043310013709_,0.013601169,0.016431025,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,2919,DB00497,10013709,729,18538,542,15833,0.017345636,1.148753129,1.024360701,1.288833346,0.055283287,DB0049710013709_,2.895284641,0.138677119,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,2920,DB00722,10013709,1142,24261,955,25077,2.23715608258279e-06,1.236023581,1.131172035,1.350854371,2.92555460849197e-05,DB0072210013709_,10.43944139,0.211899437,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,2921,DB00788,10013709,658,8698,257,4804,3.19380053964526e-06,1.414055089,1.216907591,1.646912832,4.00233836398454e-05,DB0078810013709_,10.12604668,0.346461526,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,2922,DB00814,10013709,601,7686,217,3198,0.086410675,1.152349331,0.979441511,1.359597252,0.189054818,DB0081410013709_,1.665718265,0.141802755,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,2923,DB01234,10013709,593,31032,609,32279,0.838493671,1.01285722,0.902034145,1.137232856,0.917064293,DB0123410013709_,0.086577697,0.012775267,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,2924,DB11089,10013709,261,9914,201,8206,0.477786347,1.074817745,0.888626332,1.301456012,0.643108056,DB1108910013709_,0.441442519,0.072151108,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,2925,DB00433,10051398,106,7550,131,5889,0.000570914,0.631177045,0.482735955,0.823615519,0.003447446,DB0043310051398_,5.670121755,-0.460168878,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prochlorperazine,DB00433
,2926,DB00497,10051398,109,19158,221,16154,1.26215169463173e-14,0.415884417,0.327219674,0.525981048,7.32354465637858e-13,DB0049710051398_,27.94251176,-0.8773479,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,oxycodone,DB00497
,2927,DB00635,10051398,87,32966,301,23493,8.90682057188052e-47,0.205985502,0.160261591,0.262465352,4.59050546533097e-44,DB0063510051398_,99.78975395,-1.579949493,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,2928,DB00722,10051398,73,25330,159,25873,3.50398612584614e-08,0.468970458,0.350278026,0.622865838,6.97744509983832e-07,DB0072210051398_,14.17541283,-0.757215501,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lisinopril,DB00722
,2931,DB08899,10051398,8,241,1507,6626,5.64387257045589e-13,0.145970125,0.062183501,0.293161675,2.60719139744171e-11,DB0889910051398_,24.37016247,-1.924353302,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,enzalutamide,DB08899
,2932,DB11089,10051398,83,10092,130,8277,4.13697152810412e-06,0.523662613,0.392087878,0.69609272,5.00185357020316e-05,DB1108910051398_,9.903116907,-0.646907671,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,docusate,DB11089
,2933,DB00758,10016256,441,7859,513,9561,0.504220951,1.045842795,0.915479994,1.194343372,0.665344538,DB0075810016256_,0.40745027,0.044823063,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,2934,DB00795,10016256,218,4351,48,1455,0.008834124,1.518598741,1.099777598,2.133768058,0.032235019,DB0079510016256_,3.434701869,0.417788029,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,2935,DB00814,10016256,511,7776,200,3215,0.551307744,1.056363522,0.890511797,1.25685293,0.705370135,DB0081410016256_,0.3490326,0.05483237,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,2936,DB00973,10016256,238,3613,183,2838,0.839584797,1.021574072,0.833546729,1.253538366,0.917802954,DB0097310016256_,0.085772558,0.021344646,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,2937,DB01076,10016256,1580,24167,1369,24214,0.000136915,1.156367231,1.072585634,1.246825114,0.001042986,DB0107610016256_,6.865667839,0.145283393,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,2938,DB00193,10018884,148,19172,98,8604,0.003571156,0.677753757,0.520844323,0.885192309,0.015574063,DB0019310018884_,4.162148404,-0.388971247,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,tramadol,DB00193
,2939,DB00758,10018884,148,8152,204,9870,0.256136662,0.878399723,0.704506101,1.093103616,0.416927926,DB0075810018884_,0.874841912,-0.129653524,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,clopidogrel,DB00758
,2941,DB00814,10018884,49,8238,34,3381,0.021129538,0.591509818,0.373467927,0.946636213,0.064565208,DB0081410018884_,2.74007959,-0.525076996,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,meloxicam,DB00814
,2942,DB00959,10018884,73,8005,33,4969,0.133727615,1.373113413,0.896976369,2.142367945,0.260942828,DB0095910018884_,1.343453946,0.317080726,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,methylprednisolone,DB00959
,2943,DB00973,10018884,31,3820,22,2999,0.781990024,1.106266828,0.618749526,2.009791225,0.881245376,DB0097310018884_,0.126419172,0.100991129,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ezetimibe,DB00973
,2944,DB00996,10018884,307,38646,196,22229,0.264569289,0.900947646,0.750093956,1.084197833,0.426520516,DB0099610018884_,0.852094809,-0.104308129,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,gabapentin,DB00996
,2945,DB01076,10018884,265,25482,305,25278,0.084101991,0.861900017,0.727626436,1.020440709,0.185237208,DB0107610018884_,1.686118068,-0.148616005,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,2946,DB08895,10018884,64,28050,25,6621,0.041635924,0.604281148,0.37489091,1.002331676,0.108993156,DB0889510018884_,2.216470192,-0.503715713,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,tofacitinib,DB08895
,2947,DB00193,10053762,439,18881,154,8548,0.007063985,1.290519983,1.069748617,1.56372293,0.026974191,DB0019310053762_,3.612874746,0.255045225,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,2948,DB00758,10053762,197,8103,216,9858,0.31728108,1.109564705,0.907938433,1.355344188,0.48510051,DB0075810053762_,0.723399172,0.10396778,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,2949,DB00795,10053762,76,4493,48,1455,0.000484707,0.512780984,0.350833629,0.755973087,0.003013728,DB0079510053762_,5.804577519,-0.667906457,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sulfasalazine,DB00795
,2950,DB00814,10053762,235,8052,77,3338,0.07739868,1.26515022,0.970826028,1.663991627,0.17393445,DB0081410053762_,1.749076774,0.235190866,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,meloxicam,DB00814
,2951,DB00959,10053762,417,7661,245,4757,0.511697343,1.056863091,0.896587171,1.247826012,0.672039768,DB0095910053762_,0.397437761,0.055305173,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,methylprednisolone,DB00959
,2952,DB00973,10053762,120,3731,75,2946,0.124435781,1.263317598,0.934830105,1.716276994,0.247721779,DB0097310053762_,1.395449021,0.233741275,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ezetimibe,DB00973
,2953,DB00996,10053762,1143,37810,581,21844,0.012924486,1.136590199,1.02617939,1.259859578,0.043675562,DB0099610053762_,3.13096655,0.128032726,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,2954,DB01076,10053762,609,25138,505,25078,0.002441284,1.203056091,1.066006159,1.358206102,0.011446514,DB0107610053762_,4.470070033,0.184865062,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,2955,DB08895,10053762,628,27486,202,6444,0.00017059,0.728881455,0.61955305,0.860408161,0.001261129,DB0889510053762_,6.675747629,-0.316244173,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,2956,DB00193,10062237,68,19252,39,8663,0.249348023,0.78461648,0.521235221,1.19584014,0.408763427,DB0019310062237_,0.894618708,-0.242560241,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,tramadol,DB00193
,2957,DB00758,10062237,32,8268,42,10032,0.815198609,0.924441178,0.564305231,1.501308566,0.900844843,DB0075810062237_,0.104422242,-0.078565856,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,clopidogrel,DB00758
,2960,DB00959,10062237,40,8038,42,4960,0.016731316,0.587732751,0.37088612,0.930034135,0.053695932,DB0095910062237_,2.92441803,-0.53148294,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,methylprednisolone,DB00959
,2962,DB00996,10062237,111,38842,101,22324,0.000977726,0.631678097,0.477780872,0.835850915,0.005408296,DB0099610062237_,5.219821193,-0.459375355,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,2963,DB01076,10062237,115,25632,119,25464,0.793347622,0.960041804,0.7360089,1.251903708,0.887941952,DB0107610062237_,0.118848907,-0.040778449,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,2964,DB08895,10062237,61,28053,21,6625,0.158051873,0.685998079,0.411488374,1.18702897,0.294846948,DB0889510062237_,1.221298879,-0.376880452,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,tofacitinib,DB08895
,2966,DB00193,10002034,265,19055,134,8568,0.275989941,0.889234804,0.718521193,1.104676653,0.439354122,DB0019310002034_,0.822449534,-0.117393957,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,tramadol,DB00193
,2967,DB00213,10002034,414,18481,289,13132,0.846620359,1.017906999,0.872289584,1.189083742,0.922995277,DB0021310002034_,0.080131162,0.017748558,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,pantoprazole,DB00213
,2968,DB00741,10002034,80,4014,76,3098,0.220909295,0.812447373,0.583881182,1.131271271,0.374571076,DB0074110002034_,0.981973705,-0.207704139,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,hydrocortisone,DB00741
,2969,DB00860,10002034,32,1851,33,1463,0.314022151,0.766499424,0.453950899,1.292765281,0.481581858,DB0086010002034_,0.730679057,-0.265921332,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,prednisolone,DB00860
,2970,DB00987,10002034,78,2026,128,2800,0.249284951,0.842208699,0.62343727,1.131714693,0.408698266,DB0098710002034_,0.894778132,-0.171727435,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,cytarabine,DB00987
,2971,DB01060,10002034,99,8488,80,5001,0.042660732,0.729154058,0.536384808,0.993745824,0.111034492,DB0106010002034_,2.197914388,-0.315870241,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,amoxicillin,DB01060
,2973,DB01137,10002034,169,7603,109,5484,0.389960233,1.1183631,0.871531545,1.439879207,0.559877094,DB0113710002034_,0.580037994,0.111866098,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,levofloxacin,DB01137
,2976,DB00193,10003658,160,19160,109,8593,0.001132381,0.65833689,0.512134627,0.848858165,0.006101303,DB0019310003658_,5.099252855,-0.418038488,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,tramadol,DB00193
,2977,DB00213,10003658,216,18679,230,13191,1.94675862407092e-05,0.663231348,0.547478675,0.803161896,0.000195119,DB0021310003658_,8.541902904,-0.410631409,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,2978,DB00741,10003658,26,4068,46,3128,0.000715837,0.434658407,0.257313433,0.719907243,0.004169698,DB0074110003658_,5.479911569,-0.833194827,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,hydrocortisone,DB00741
,2981,DB01060,10003658,45,8542,58,5023,8.52125098016397e-05,0.456255696,0.301566607,0.686410964,0.000696107,DB0106010003658_,7.270007687,-0.78470189,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,amoxicillin,DB01060
,2983,DB01137,10003658,74,7698,86,5507,0.002746196,0.615597245,0.444047209,0.851625992,0.012576665,DB0113710003658_,4.375912131,-0.485162352,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,levofloxacin,DB01137
,3005,DB00099,10021097,34,2351,37,1918,0.23172126,0.749731309,0.454582752,1.233027971,0.387997953,DB0009910021097_,0.946755214,-0.288040391,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,filgrastim,DB00099
,3006,DB00193,10021097,242,19078,162,8540,0.00011493,0.668697452,0.544850607,0.822426363,0.000898287,DB0019310021097_,7.015020388,-0.40242356,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,tramadol,DB00193
,3007,DB00741,10021097,119,3975,121,3053,0.03418017,0.755392089,0.57888115,0.985589269,0.093776502,DB0074110021097_,2.366840966,-0.280518342,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,hydrocortisone,DB00741
,3009,DB00987,10021097,130,1974,149,2779,0.104369502,1.228223624,0.95621343,1.576084394,0.217562344,DB0098710021097_,1.525269832,0.205568918,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,cytarabine,DB00987
,3010,DB01060,10021097,83,8504,80,5001,0.001890973,0.610179748,0.442424604,0.841849843,0.009291378,DB0106010021097_,4.678668391,-0.494001696,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,amoxicillin,DB01060
,3011,DB01073,10021097,69,996,109,1541,0.936791625,0.979419353,0.706015336,1.351307245,0.976854361,DB0107310021097_,0.023417706,-0.02079538,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,fludarabine,DB01073
,3012,DB01137,10021097,116,7656,144,5449,1.06317911789119e-05,0.57337613,0.443912329,0.739255183,0.000114476,DB0113710021097_,9.07514163,-0.556213355,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,levofloxacin,DB01137
,3013,DB01263,10021097,17,607,39,826,0.096770051,0.593363165,0.311604555,1.08579226,0.205942903,DB0126310021097_,1.58015632,-0.521948648,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,posaconazole,DB01263
,3014,DB00213,10028813,1320,17575,557,12864,1.01360847816661e-27,1.734568615,1.565588125,1.923610889,1.9306303513485e-25,DB0021310028813_,56.90678077,0.550758746,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,3015,DB00741,10028813,277,3817,141,3033,2.35921724108629e-05,1.560932055,1.262457521,1.936675109,0.000229887,DB0074110028813_,8.377922562,0.445283114,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,hydrocortisone,DB00741
,3016,DB00860,10028813,86,1797,39,1457,0.003175515,1.787611375,1.202554931,2.698890946,0.014173613,DB0086010028813_,4.256373285,0.580880301,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,prednisolone,DB00860
,3017,DB00987,10028813,119,1985,147,2781,0.338194031,1.134117879,0.876794262,1.464549682,0.507257274,DB0098710028813_,0.678736959,0.12585515,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cytarabine,DB00987
,3018,DB01060,10028813,466,8121,178,4903,2.04131115001859e-07,1.580535365,1.321941204,1.896177949,3.45498155687305e-06,DB0106010028813_,12.57569344,0.457763628,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,3019,DB01073,10028813,47,1018,57,1593,0.219490521,1.29015772,0.850570483,1.949110529,0.372850897,DB0107310028813_,0.98657668,0.254764475,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fludarabine,DB01073
,3020,DB01137,10028813,415,7357,208,5385,1.00335232793659e-05,1.460350686,1.228619107,1.739901857,0.000108934,DB0113710028813_,9.124768686,0.378676603,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,3022,DB00099,10035664,82,2303,101,1854,0.006140435,0.653668504,0.479170375,0.889533119,0.02410414,DB0009910035664_,3.725371663,-0.42515493,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,filgrastim,DB00099
,3023,DB00193,10035664,579,18741,332,8370,0.00041131,0.778862172,0.67767827,0.896340664,0.002621871,DB0019310035664_,5.943867135,-0.249921178,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,tramadol,DB00193
,3024,DB00213,10035664,882,18013,668,12753,0.204854475,0.93480178,0.842217211,1.037901537,0.354892066,DB0021310035664_,1.035941575,-0.067420772,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,3025,DB00741,10035664,137,3957,136,3038,0.040039532,0.77343269,0.602615547,0.992703905,0.105762145,DB0074110035664_,2.24656262,-0.256916633,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,hydrocortisone,DB00741
,3026,DB00860,10035664,59,1824,71,1425,0.018925382,0.649302358,0.448490382,0.937123179,0.05916081,DB0086010035664_,2.827495944,-0.431856788,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,prednisolone,DB00860
,3027,DB00987,10035664,76,2028,110,2818,0.820501948,0.960052792,0.702975482,1.305506555,0.90436707,DB0098710035664_,0.10051995,-0.040767005,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cytarabine,DB00987
,3028,DB01060,10035664,293,8294,257,4824,3.28763513573641e-06,0.663146124,0.556761974,0.790165942,4.09987988442498e-05,DB0106010035664_,10.10196779,-0.410759915,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,3029,DB01073,10035664,43,1022,72,1578,0.697697888,0.922143764,0.611626332,1.376214832,0.818237054,DB0107310035664_,0.200603187,-0.081054141,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,fludarabine,DB01073
,3030,DB01137,10035664,502,7270,475,5118,9.96844799242179e-06,0.744033046,0.651620434,0.849596835,0.000108295,DB0113710035664_,9.130648127,-0.295669829,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,levofloxacin,DB01137
,3031,DB01263,10035664,30,594,57,808,0.178797075,0.716088268,0.438398733,1.149317834,0.322392805,DB0126310035664_,1.131984586,-0.33395184,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,posaconazole,DB01263
,3032,DB00099,10037660,126,2259,119,1836,0.261597354,0.860589616,0.659299069,1.123878343,0.423210603,DB0009910037660_,0.859885345,-0.150137525,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,filgrastim,DB00099
,3033,DB00193,10037660,318,19002,195,8507,0.000736577,0.730071138,0.607773117,0.878768038,0.004267339,DB0019310037660_,5.456764805,-0.3146133,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,3034,DB00213,10037660,433,18462,343,13078,0.130634073,0.894249242,0.772906051,1.035265116,0.256668904,DB0021310037660_,1.359968335,-0.111770749,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,3035,DB00741,10037660,131,3963,159,3015,0.00010564,0.626865051,0.491106431,0.798993538,0.000836564,DB0074110037660_,7.086207254,-0.467023992,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,3036,DB00860,10037660,75,1808,99,1397,0.000715545,0.585466649,0.424176157,0.805249127,0.004168463,DB0086010037660_,5.480207918,-0.535346059,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,prednisolone,DB00860
,3037,DB00987,10037660,186,1918,256,2672,0.91961121,1.012187234,0.825803744,1.238917068,0.964404362,DB0098710037660_,0.03624461,0.012113568,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,cytarabine,DB00987
,3038,DB01060,10037660,220,8367,161,4920,0.040951041,0.803536244,0.650632607,0.993995452,0.107564516,DB0106010037660_,2.229664461,-0.218732987,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,3039,DB01073,10037660,167,898,252,1398,0.785740041,1.031691889,0.828362414,1.282633462,0.883734037,DB0107310037660_,0.123599125,0.031200065,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,fludarabine,DB01073
,3040,DB01137,10037660,254,7518,291,5302,3.40939953255227e-08,0.615609478,0.516227541,0.733743124,6.80973151315626e-07,DB0113710037660_,14.19974296,-0.485142481,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,3041,DB01263,10037660,27,597,43,822,0.620527932,0.864652976,0.507566574,1.449945813,0.761056234,DB0126310037660_,0.273048029,-0.145427036,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,posaconazole,DB01263
,3046,DB00987,10038687,24,2080,39,2889,0.608130539,0.854775792,0.490072154,1.462631562,0.750956786,DB0098710038687_,0.286407171,-0.156916076,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cytarabine,DB00987
,3049,DB01137,10038687,28,7744,35,5558,0.029619874,0.574211402,0.336030192,0.972792086,0.083869255,DB0113710038687_,2.478496182,-0.554757655,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,3051,DB00099,10040047,52,2333,60,1895,0.068154647,0.70402289,0.473637174,1.043525719,0.157982705,DB0009910040047_,1.845269713,-0.350944409,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,filgrastim,DB00099
,3052,DB00193,10040047,165,19155,134,8568,5.74686738253782e-07,0.550819916,0.435213364,0.698115849,8.76705798897311e-06,DB0019310040047_,11.64450927,-0.596347354,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,tramadol,DB00193
,3053,DB00213,10040047,249,18646,284,13137,4.3610334069134e-08,0.617744475,0.518188881,0.73603736,8.53217440273307e-07,DB0021310040047_,13.97425141,-0.481680378,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,3054,DB00741,10040047,83,4011,94,3080,0.011280554,0.678076177,0.496608282,0.924429829,0.039176767,DB0074110040047_,3.239671378,-0.388495641,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,hydrocortisone,DB00741
,3055,DB00860,10040047,32,1851,44,1452,0.01903996,0.570608024,0.348288873,0.925638185,0.059462407,DB0086010040047_,2.822410978,-0.561052778,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,prednisolone,DB00860
,3056,DB00987,10040047,122,1982,187,2741,0.405104947,0.90223283,0.70694177,1.148284306,0.574785217,DB0098710040047_,0.553758843,-0.102882666,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,cytarabine,DB00987
,3057,DB01060,10040047,65,8522,89,4992,2.14212617655185e-07,0.427839397,0.305242979,0.59695976,3.60587810122737e-06,DB0106010040047_,12.53294524,-0.849007395,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,3058,DB01073,10040047,30,1035,55,1595,0.499113241,0.840652398,0.516362438,1.345167998,0.660983036,DB0107310040047_,0.414027104,-0.173577025,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,fludarabine,DB01073
,3059,DB01137,10040047,135,7637,158,5435,2.63047337721647e-05,0.60810774,0.478383806,0.772151102,0.000252343,DB0113710040047_,8.28472113,-0.497403209,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,levofloxacin,DB01137
,3060,DB01263,10040047,21,603,32,833,0.778209795,0.906595857,0.491633137,1.639713426,0.879072925,DB0126310040047_,0.128887421,-0.09805851,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,posaconazole,DB01263
,3061,DB00099,10043554,68,2317,65,1890,0.377232083,0.853391511,0.594958547,1.224982996,0.547124941,DB0009910043554_,0.603078092,-0.158536855,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,filgrastim,DB00099
,3062,DB00193,10043554,77,19243,62,8640,0.000868099,0.557661593,0.3935266,0.7929673,0.004904457,DB0019310043554_,5.317610876,-0.584002965,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,tramadol,DB00193
,3063,DB00213,10043554,125,18770,151,13270,1.19052359113328e-05,0.585272228,0.457524225,0.747559619,0.000126436,DB0021310043554_,8.975774224,-0.535678193,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,pantoprazole,DB00213
,3064,DB00741,10043554,36,4058,44,3130,0.041779705,0.63112796,0.393654784,1.00589863,0.109282471,DB0074110043554_,2.21381927,-0.460246648,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,hydrocortisone,DB00741
,3066,DB00987,10043554,106,1998,163,2765,0.445934367,0.89993876,0.693088896,1.164679085,0.61378923,DB0098710043554_,0.488103683,-0.105428563,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,cytarabine,DB00987
,3067,DB01060,10043554,31,8556,53,5028,2.00096656742041e-06,0.343751963,0.212979473,0.546248186,2.64840461983645e-05,DB0106010043554_,10.53896804,-1.06783492,male,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,amoxicillin,DB01060
,3068,DB01073,10043554,38,1027,61,1589,0.916676245,0.963854895,0.620378527,1.481014997,0.962849812,DB0107310043554_,0.037857838,-0.03681452,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,fludarabine,DB01073
,3069,DB01137,10043554,69,7703,88,5505,0.000327,0.560394029,0.402049038,0.778397534,0.00216558,DB0113710043554_,6.135066993,-0.57911512,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,levofloxacin,DB01137
,3094,DB00073,10005734,31,7375,46,6361,0.021521382,0.581285271,0.355849247,0.93787433,0.065507444,DB0007310005734_,2.725591487,-0.542513643,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,rituximab,DB00073
,3095,DB00169,10005734,142,38549,68,18107,0.882409009,0.980873068,0.729198323,1.330430352,0.950859822,DB0016910005734_,0.050388628,-0.019312218,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,3096,DB00186,10005734,60,16841,25,9983,0.14524717,1.422652871,0.877944584,2.369593803,0.277397505,DB0018610005734_,1.282303765,0.352523347,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,lorazepam,DB00186
,3097,DB00213,10005734,68,18827,55,13366,0.521237022,0.877746967,0.605675561,1.276965121,0.680071236,DB0021310005734_,0.385557728,-0.13039692,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,3098,DB00316,10005734,188,65286,135,36818,0.036539223,0.785369344,0.6259727,0.987483943,0.098650215,DB0031610005734_,2.316174871,-0.24160117,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,3099,DB00437,10005734,21,6900,55,11491,0.095694783,0.635880527,0.364923241,1.069704016,0.20432455,DB0043710005734_,1.588045619,-0.452744584,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,allopurinol,DB00437
,3101,DB00722,10005734,110,25293,103,25929,0.536817776,1.094799918,0.828667072,1.447442735,0.693055097,DB0072210005734_,0.366645778,0.090571623,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,lisinopril,DB00722
,3102,DB00758,10005734,30,8270,67,10007,0.005484173,0.541830657,0.33964959,0.846107975,0.022026358,DB0075810005734_,3.815515453,-0.612801767,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,clopidogrel,DB00758
,3103,DB00904,10005734,77,22992,46,14410,0.852975264,1.049111006,0.718373417,1.547196807,0.928147027,DB0090410005734_,0.074565124,0.047943145,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,ondansetron,DB00904
,3104,DB01136,10005734,62,9822,96,11019,0.05458102,0.724553286,0.517156134,1.008766222,0.133593641,DB0113610005734_,2.012952619,-0.322199972,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,carvedilol,DB01136
,3106,DB11089,10005734,37,10138,33,8374,0.810159045,0.926131444,0.562919634,1.529550379,0.897832552,DB1108910005734_,0.107771696,-0.076739106,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,docusate,DB11089
,3107,DB00073,10019303,37,7369,17,6390,0.02889463,1.887229783,1.035263274,3.577832288,0.082245422,DB0007310019303_,2.498047554,0.635110031,NA,10019303,Heart rate increased,10022891,Investigations,Inv,rituximab,DB00073
,3108,DB00169,10019303,188,38503,73,18102,0.18325906,1.210760872,0.918771432,1.610113762,0.327966539,DB0016910019303_,1.11484369,0.191248982,NA,10019303,Heart rate increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,3109,DB00186,10019303,96,16805,47,9961,0.298954464,1.210651491,0.844738212,1.756452109,0.464916464,DB0018610019303_,0.765897537,0.191158637,NA,10019303,Heart rate increased,10022891,Investigations,Inv,lorazepam,DB00186
,3110,DB00213,10019303,100,18795,56,13365,0.166331119,1.269799785,0.905833158,1.795613669,0.305907665,DB0021310019303_,1.184471972,0.238859239,NA,10019303,Heart rate increased,10022891,Investigations,Inv,pantoprazole,DB00213
,3111,DB00316,10019303,320,65154,127,36826,0.000647485,1.42415819,1.155510842,1.763945478,0.003837895,DB0031610019303_,5.562831172,0.353580895,NA,10019303,Heart rate increased,10022891,Investigations,Inv,acetaminophen,DB00316
,3112,DB00437,10019303,34,6887,40,11506,0.148590841,1.420009089,0.870956054,2.303355192,0.282031285,DB0043710019303_,1.265737274,0.350663273,NA,10019303,Heart rate increased,10022891,Investigations,Inv,allopurinol,DB00437
,3114,DB00722,10019303,134,25269,83,25949,0.000293112,1.657876068,1.25078756,2.208300995,0.001980539,DB0072210019303_,6.224386074,0.505537306,NA,10019303,Heart rate increased,10022891,Investigations,Inv,lisinopril,DB00722
,3115,DB00758,10019303,47,8253,31,10043,0.008467561,1.844876411,1.146605325,3.006705575,0.031167041,DB0075810019303_,3.468394121,0.612412289,NA,10019303,Heart rate increased,10022891,Investigations,Inv,clopidogrel,DB00758
,3116,DB00904,10019303,126,22943,62,14394,0.132767605,1.274972256,0.932746206,1.7585845,0.259657477,DB0090410019303_,1.348391913,0.242924418,NA,10019303,Heart rate increased,10022891,Investigations,Inv,ondansetron,DB00904
,3117,DB01136,10019303,58,9826,39,11076,0.014067357,1.676310499,1.096999509,2.586403773,0.046775519,DB0113610019303_,3.062395305,0.516595247,NA,10019303,Heart rate increased,10022891,Investigations,Inv,carvedilol,DB01136
,3118,DB11089,10019303,52,10123,32,8375,0.226671885,1.344378346,0.848414772,2.160321401,0.381780757,DB1108910019303_,0.96290877,0.29593171,NA,10019303,Heart rate increased,10022891,Investigations,Inv,docusate,DB11089
,3119,DB00073,10021036,27,7379,34,6373,0.157521681,0.685878322,0.397576537,1.172555097,0.294202441,DB0007310021036_,1.223487172,-0.37705504,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,rituximab,DB00073
,3120,DB00169,10021036,130,38561,66,18109,0.592268995,0.925011465,0.682308709,1.264291003,0.738465935,DB0016910021036_,0.303180305,-0.077949147,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,3121,DB00186,10021036,107,16794,71,9937,0.483905362,0.891722583,0.653784195,1.222608957,0.648157992,DB0018610021036_,0.433620798,-0.114600201,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,lorazepam,DB00186
,3122,DB00213,10021036,74,18821,84,13337,0.003474938,0.624287415,0.45011772,0.864332647,0.015232009,DB0021310021036_,4.184356195,-0.471144416,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,3123,DB00316,10021036,213,65261,159,36794,0.00801234,0.755298305,0.611867607,0.933820913,0.029817156,DB0031610021036_,3.512671349,-0.280642502,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,3124,DB00437,10021036,41,6880,56,11490,0.344627654,1.222693733,0.79586559,1.864559394,0.514020967,DB0043710021036_,0.665491222,0.201056402,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,allopurinol,DB00437
,3126,DB00722,10021036,96,25307,115,25917,0.270018253,0.854907574,0.644703139,1.131482762,0.432677768,DB0072210021036_,0.837762012,-0.156761916,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,3127,DB00758,10021036,17,8283,41,10033,0.016880533,0.502261862,0.267338715,0.904544672,0.054103744,DB0075810021036_,2.916851896,-0.688633658,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,clopidogrel,DB00758
,3128,DB00904,10021036,142,22927,115,14341,0.045964145,0.772383298,0.599152676,0.997359086,0.117417517,DB0090410021036_,2.142019171,-0.258274352,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,3129,DB01136,10021036,30,9854,39,11076,0.629319699,0.864629892,0.518288228,1.429372066,0.768361395,DB0113610021036_,0.26349509,-0.145453734,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,carvedilol,DB01136
,3131,DB11089,10021036,78,10097,75,8332,0.36995569,0.85821225,0.616096817,1.196109382,0.539607511,DB1108910021036_,0.616913235,-0.152903832,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,3132,DB00073,10028813,370,7036,244,6163,0.000787909,1.328215249,1.122716103,1.573499482,0.004516944,DB0007310028813_,5.39991963,0.283836123,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,rituximab,DB00073
,3133,DB00186,10028813,1462,15439,487,9521,1.76902140083092e-32,1.851275384,1.664329644,2.061978725,4.58115542077248e-30,DB0018610028813_,67.55560155,0.615874799,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,3134,DB00437,10028813,418,6503,410,11136,8.60473024751321e-15,1.745716956,1.514506815,2.012564743,5.11708901710146e-13,DB0043710028813_,28.30102048,0.557165334,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,3136,DB00758,10028813,438,7862,337,9737,1.17852009880188e-10,1.609600603,1.388879319,1.866680649,3.79392538848836e-09,DB0075810028813_,19.38986463,0.475986076,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,3137,DB00904,10028813,2685,20384,1121,13335,7.49966205467582e-35,1.566883049,1.455855619,1.687192382,2.27894355037172e-32,DB0090410028813_,72.859011,0.449088327,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,3138,DB01136,10028813,560,9324,384,10731,1.27897885377448e-14,1.678334556,1.466804676,1.921854869,7.41300091983731e-13,DB0113610028813_,27.93037087,0.517801966,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,3144,DB00316,10037596,50,65424,16,36937,0.053672848,1.764298401,0.987945579,3.319714761,0.13188736,DB0031610037596_,2.025807054,0.567753105,NA,10037596,Pyelonephritis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,3157,DB00316,10052238,44,65430,20,36933,0.515231251,1.241863914,0.716548787,2.22451818,0.675066841,DB0031610052238_,0.392943569,0.216613407,NA,10052238,Escherichia urinary tract infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,3166,DB00363,10001497,38,4590,59,6829,0.917262057,0.958243137,0.618958839,1.467692288,0.963253422,DB0036310001497_,0.037438743,-0.042653737,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,3169,DB08815,10026749,39,1415,20,683,0.888104868,0.941264331,0.531111628,1.717113688,0.953646495,DB0881510026749_,0.047462226,-0.060531275,NA,10026749,Mania,10037175,Psychiatric disorders,Psych,lurasidone,DB08815
,3170,DB00363,10028813,52,4576,68,6820,0.512668405,1.139689546,0.777061674,1.663123989,0.672851533,DB0036310028813_,0.396230578,0.130755898,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,clozapine,DB00363
,3171,DB08815,10028813,64,1390,31,672,1,0.998097766,0.633353625,1.602343904,1,DB0881510028813_,0,-0.001904046,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lurasidone,DB08815
,3172,DB08815,10047700,44,1410,18,685,0.585252822,1.187437834,0.666346955,2.20072641,0.732792639,DB0881510047700_,0.310892511,0.171797905,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lurasidone,DB08815
,3174,DB06589,10011906,250,1780,369,2284,0.117060243,0.869366391,0.728723902,1.036010826,0.236705016,DB0658910011906_,1.440940573,-0.139990619,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pazopanib,DB06589
,3179,DB00497,10035664,631,18636,711,15664,1.47453492228355e-07,0.745961887,0.667645326,0.833341897,2.58301569025146e-06,DB0049710035664_,12.86655297,-0.29308077,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,oxycodone,DB00497
,3180,DB00497,10047700,736,18531,438,15937,1.37236591532293e-09,1.445126259,1.279637693,1.633446439,3.71308678170491e-08,DB0049710047700_,17.1088172,0.368196695,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,3183,DB00158,10002034,309,16506,162,7942,0.398603374,0.917770558,0.754909056,1.119084606,0.568438871,DB0015810002034_,0.564861498,-0.085807857,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,folic acid,DB00158
,3184,DB00169,10002034,643,38048,320,17855,0.402971208,0.942952642,0.822340491,1.082953519,0.572716115,DB0016910002034_,0.557365121,-0.058739218,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,3185,DB00335,10002034,144,8322,102,5363,0.469394853,0.90980013,0.699362057,1.187144921,0.635735861,DB0033510002034_,0.452972115,-0.094530341,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,atenolol,DB00335
,3187,DB00433,10002034,234,7422,161,5859,0.198541902,1.147316724,0.931814848,1.415443162,0.347309589,DB0043310002034_,1.057538708,0.137425933,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,prochlorperazine,DB00433
,3188,DB00451,10002034,745,46526,254,15165,0.529271088,0.956022493,0.827002905,1.108064336,0.686570156,DB0045110002034_,0.376046865,-0.044973838,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,levothyroxine,DB00451
,3189,DB00512,10002034,94,4643,77,5021,0.075970031,1.320123068,0.963637176,1.813109649,0.171426953,DB0051210002034_,1.763598032,0.277724966,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,vancomycin,DB00512
,3190,DB00653,10002034,42,1050,23,799,0.251290151,1.389331109,0.809012724,2.441445933,0.411229088,DB0065310002034_,0.888604827,0.328822415,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,magnesium sulfate,DB00653
,3191,DB00761,10002034,480,14827,257,8368,0.508035362,1.05408925,0.90177537,1.234309698,0.668691904,DB0076110002034_,0.402431856,0.052677124,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,potassium chloride,DB00761
,3192,DB00863,10002034,175,10498,104,5736,0.527774875,0.919412181,0.715596605,1.186127459,0.685267862,DB0086310002034_,0.377945478,-0.084020747,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ranitidine,DB00863
,3193,DB00904,10002034,626,22443,334,14122,0.01702999,1.179308871,1.029243143,1.353231779,0.054466543,DB0090410002034_,2.910168663,0.164928564,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ondansetron,DB00904
,3194,DB00916,10002034,97,5226,23,2408,0.003814553,1.94311538,1.219684685,3.217280589,0.016412757,DB0091610002034_,4.109696358,0.664292551,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,metronidazole,DB00916
,3195,DB00959,10002034,136,7942,96,4906,0.340060452,0.875127895,0.667246244,1.151497226,0.509214059,DB0095910002034_,0.674886803,-0.133385238,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,methylprednisolone,DB00959
,3196,DB00999,10002034,331,21099,179,12060,0.577922861,1.05696749,0.877307737,1.276799935,0.726775705,DB0099910002034_,0.31913737,0.055403949,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,hydrochlorothiazide,DB00999
,3197,DB01015,10002034,174,9713,223,9158,0.002731296,0.735699953,0.598615528,0.902988037,0.012519334,DB0101510002034_,4.380481144,-0.306932916,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,sulfamethoxazole,DB01015
,3198,DB01050,10002034,180,17928,149,9222,2.38617555696349e-05,0.621403606,0.4965901,0.778528491,0.000232069,DB0105010002034_,8.368477145,-0.475774479,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ibuprofen,DB01050
,3199,DB01225,10002034,156,4888,173,4467,0.092028997,0.82408691,0.656829838,1.033230615,0.198464304,DB0122510002034_,1.617146022,-0.193479282,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,enoxaparin,DB01225
,3200,DB01373,10002034,377,22343,121,7260,0.958118712,1.012399639,0.821317801,1.255198045,0.99577519,DB0137310002034_,0.004233759,0.012323393,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,calcium,DB01373
,3201,DB06186,10002034,47,2162,45,3601,0.009100715,1.739366551,1.126688791,2.688395109,0.03301985,DB0618610002034_,3.410646397,0.553520996,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ipilimumab,DB06186
,3202,DB09035,10002034,97,4629,83,6607,0.000752702,1.667937056,1.228229565,2.269441988,0.004345438,DB0903510002034_,5.438628727,0.511587567,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,nivolumab,DB09035
,3203,DB09153,10002034,117,7682,92,5607,0.621493015,0.928232803,0.69872715,1.236173821,0.761777794,DB0915310002034_,0.272100374,-0.074472712,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,sodium chloride,DB09153
,3230,DB00158,10037660,345,16470,155,7949,0.499633515,1.074247822,0.884466848,1.309484305,0.661372159,DB0015810037660_,0.413438574,0.071620716,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,3231,DB00169,10037660,790,37901,434,17741,0.008443155,0.852063378,0.75589024,0.96145136,0.031095463,DB0016910037660_,3.470693369,-0.160094368,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,3232,DB00316,10037660,1450,64024,1021,35932,5.53648383235723e-08,0.797057311,0.734427974,0.865246405,1.06107530100992e-06,DB0031610037660_,13.75622773,-0.226828695,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,3233,DB00335,10037660,112,8354,88,5377,0.166406279,0.819202135,0.612719929,1.098138145,0.305991048,DB0033510037660_,1.184199433,-0.199424419,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,3234,DB00355,10037660,42,1751,43,1220,0.093358734,0.680643541,0.43119997,1.073620224,0.200706198,DB0035510037660_,1.605913141,-0.384716545,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,aztreonam,DB00355
,3235,DB00433,10037660,297,7359,233,5787,1,1.002386348,0.838521377,1.199362341,1,DB0043310037660_,0,0.002383506,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,3236,DB00451,10037660,898,46373,334,15085,0.041494679,0.874620576,0.769429303,0.996032746,0.108731695,DB0045110037660_,2.218871944,-0.133965114,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,3237,DB00512,10037660,230,4507,290,4808,0.071199708,0.846086071,0.705067074,1.014414649,0.163384202,DB0051210037660_,1.811650786,-0.167134186,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,3238,DB00635,10037660,984,32069,772,23022,0.072855232,0.915032425,0.830600688,1.008295901,0.166290358,DB0063510037660_,1.794019872,-0.088795777,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,3239,DB00653,10037660,56,1036,46,776,0.681504518,0.911913348,0.599175489,1.3937346,0.807434868,DB0065310037660_,0.213892886,-0.092210306,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,magnesium sulfate,DB00653
,3240,DB00761,10037660,442,14865,263,8362,0.473918796,0.945394385,0.807781511,1.108209333,0.63973683,DB0076110037660_,0.44669839,-0.0561531,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,3241,DB00863,10037660,307,10366,177,5663,0.595628461,0.947549938,0.782620489,1.149990404,0.74122358,DB0086310037660_,0.299452972,-0.053875638,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,3242,DB00904,10037660,800,22269,607,13849,0.000314212,0.819644672,0.735032512,0.914288601,0.002096476,DB0090410037660_,6.167497644,-0.19888436,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,3243,DB00916,10037660,126,5197,114,2317,1.28007195520673e-07,0.492799097,0.377562057,0.643766697,2.27584792644719e-06,DB0091610037660_,12.99315786,-0.7076537,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,3244,DB00959,10037660,266,7812,190,4812,0.128554621,0.862379914,0.710608835,1.048116229,0.253587859,DB0095910037660_,1.372044932,-0.14805937,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,3245,DB00999,10037660,355,21075,208,12031,0.790967394,0.974298984,0.817521163,1.163569075,0.886724158,DB0099910037660_,0.120221329,-0.026037058,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,3246,DB01015,10037660,368,9519,447,8934,0.00033897,0.772685034,0.669210347,0.891737401,0.002233321,DB0101510037660_,6.104265656,-0.257883773,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,3247,DB01050,10037660,384,17724,243,9128,0.013463446,0.813861019,0.689819014,0.96160016,0.045104449,DB0105010037660_,3.098774386,-0.205965666,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,3248,DB01075,10037660,661,19287,413,10684,0.060251918,0.886592645,0.781000084,1.007316041,0.143920988,DB0107510037660_,1.938490825,-0.120369652,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,3249,DB01225,10037660,181,4863,187,4453,0.264196566,0.886321267,0.715464085,1.097777914,0.426102576,DB0122510037660_,0.853075172,-0.120675791,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,3250,DB01373,10037660,363,22357,148,7233,0.022363328,0.793509543,0.652411824,0.969097891,0.067437627,DB0137310037660_,2.69655215,-0.231289713,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,3251,DB06186,10037660,86,2123,150,3496,0.731875806,0.944126232,0.711636167,1.246165464,0.844169453,DB0618610037660_,0.169402031,-0.057495401,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ipilimumab,DB06186
,3252,DB09035,10037660,148,4578,232,6458,0.340565493,0.899886142,0.724605331,1.114812536,0.509767033,DB0903510037660_,0.673801456,-0.105487032,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,nivolumab,DB09035
,3253,DB09153,10037660,276,7523,261,5438,0.002417452,0.764417006,0.640672896,0.91222632,0.011357058,DB0915310037660_,4.477915914,-0.26864182,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,3255,DB00169,10046274,38,38653,31,18144,0.02731369,0.575398561,0.348520094,0.956699383,0.078687018,DB0016910046274_,2.542277091,-0.552692329,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,3256,DB00213,10046274,45,18850,67,13354,0.000106842,0.475819808,0.318475716,0.705108753,0.000844616,DB0021310046274_,7.076628512,-0.74271605,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,3257,DB00316,10046274,71,65403,75,36878,0.000186722,0.533771073,0.380236764,0.748709701,0.001361816,DB0031610046274_,6.598935833,-0.627788234,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,3261,DB00451,10046274,45,47226,27,15392,0.013656695,0.54322559,0.329719624,0.910798519,0.045646775,DB0045110046274_,3.086822325,-0.610230594,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,3263,DB00635,10046274,23,33030,41,23753,0.000510357,0.40342113,0.23100067,0.688513291,0.003139783,DB0063510046274_,5.763601704,-0.907774275,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,3265,DB00761,10046274,28,15279,32,8593,0.006756073,0.492109294,0.285284823,0.844386777,0.026053996,DB0076110046274_,3.647584137,-0.709054444,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,3270,DB00999,10046274,27,21403,33,12206,0.0043406,0.466607389,0.26975232,0.800661166,0.018247726,DB0099910046274_,4.003714814,-0.762267083,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,3272,DB01050,10046274,23,18085,43,9328,3.17332943348539e-07,0.275892124,0.158618765,0.468435356,5.13930771159355e-06,DB0105010046274_,12.17859217,-1.287745346,male,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,3282,DB00213,10050953,27,18868,30,13391,0.105912221,0.638771598,0.365184652,1.112290956,0.22004527,DB0021310050953_,1.513921983,-0.448208326,NA,10050953,Lower gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,3283,DB00316,10050953,52,65422,47,36906,0.021023466,0.624108678,0.412455667,0.946709643,0.064308368,DB0031610050953_,2.744065515,-0.471430762,NA,10050953,Lower gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,3287,DB00451,10050953,43,47228,17,15402,0.548185664,0.824875372,0.460623288,1.543215692,0.70266837,DB0045110050953_,0.352870233,-0.192522968,NA,10050953,Lower gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,3332,DB00363,10039626,53,4575,101,6787,0.159432591,0.778485677,0.546236366,1.098526452,0.296696802,DB0036310039626_,1.215044529,-0.250404686,NA,10039626,Schizophrenia,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,3333,DB00188,10003549,224,7662,270,8558,0.410681049,0.92662372,0.770623254,1.113455315,0.580082292,DB0018810003549_,0.544585303,-0.076207707,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,3334,DB00188,10007559,69,7817,86,8742,0.518852424,0.897285783,0.643036929,1.24814145,0.678070698,DB0018810007559_,0.388503722,-0.108380869,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,bortezomib,DB00188
,3335,DB00188,10020772,46,7840,29,8799,0.014837264,1.780154957,1.093586848,2.941588204,0.048887182,DB0018810020772_,3.018240048,0.576700415,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,bortezomib,DB00188
,3336,DB00188,10035664,372,7514,525,8303,0.000448973,0.782987212,0.681179556,0.899273191,0.002822927,DB0018810035664_,5.869981007,-0.244638915,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,bortezomib,DB00188
,3340,DB00811,10022004,63,2735,92,4064,0.934084515,1.017537502,0.72371934,1.422880959,0.974650132,DB0081110022004_,0.025676711,0.017385495,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,3341,DB00186,10000081,377,16524,158,9850,0.000205525,1.42232808,1.176058618,1.726585218,0.001474001,DB0018610000081_,6.519775008,0.352295022,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,3342,DB00295,10000081,235,14428,134,9468,0.217252128,1.150873373,0.925329533,1.436010372,0.370205693,DB0029510000081_,0.993696501,0.140521109,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,3343,DB00327,10000081,200,5938,85,4177,8.82459376998693e-05,1.65506203,1.273624876,2.166030265,0.000717348,DB0032710000081_,7.239949603,0.503838488,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,hydromorphone,DB00327
,3344,DB00557,10000081,102,5885,40,3027,0.153725125,1.311603651,0.898960522,1.946381977,0.289114547,DB0055710000081_,1.240932314,0.271250549,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,hydroxyzine,DB00557
,3345,DB00572,10000081,102,2800,56,2070,0.085602827,1.34647713,0.957462455,1.91005238,0.187732145,DB0057210000081_,1.672739091,0.297491648,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,atropine,DB00572
,3346,DB00588,10000081,286,16238,95,8373,0.000161437,1.552329207,1.224700012,1.982174975,0.001201408,DB0058810000081_,6.724261239,0.439756517,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,3347,DB00646,10000081,86,3367,35,1965,0.085585236,1.43391209,0.953267559,2.198306565,0.187701955,DB0064610000081_,1.672899918,0.360406436,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,nystatin,DB00646
,3348,DB00889,10000081,48,732,27,490,0.544163292,1.189869986,0.716550038,2.012220359,0.699241384,DB0088910000081_,0.357759268,0.173844045,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,granisetron,DB00889
,3350,DB00996,10000081,472,38481,230,22195,0.036739561,1.183681175,1.008003744,1.393031246,0.099046087,DB0099610000081_,2.312170009,0.168629222,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,3351,DB06589,10000081,48,1982,42,2611,0.06730195,1.505391323,0.969788728,2.3448149,0.156500478,DB0658910000081_,1.854696214,0.40905288,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,pazopanib,DB06589
,3352,DB09153,10000081,141,7658,84,5615,0.152771408,1.230743227,0.930621572,1.636035229,0.287825517,DB0915310000081_,1.245400828,0.207618237,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,3353,DB14512,10000081,56,4788,25,2387,0.722505592,1.116703137,0.683407278,1.872734853,0.836639156,DB1451210000081_,0.178362417,0.110380717,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,mometasone furoate,DB14512
,3354,DB00186,10003549,522,16379,271,9737,0.079591526,1.145111889,0.984683467,1.33389315,0.177745393,DB0018610003549_,1.727403131,0.135502352,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,3355,DB00295,10003549,270,14393,221,9381,0.013463554,0.796302977,0.662798496,0.957452655,0.045104449,DB0029510003549_,3.098774386,-0.227775541,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,3356,DB00327,10003549,162,5976,87,4175,0.050558756,1.300860372,0.993237679,1.713331,0.126019336,DB0032710003549_,2.071319923,0.26302587,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,3357,DB00557,10003549,140,5847,67,3000,0.710377177,1.072112278,0.792869527,1.461805614,0.827231264,DB0055710003549_,0.189670981,0.069630794,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,3358,DB00572,10003549,134,2768,84,2042,0.262686129,1.176790332,0.883602176,1.574570349,0.424447819,DB0057210003549_,0.856966205,0.162790674,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,atropine,DB00572
,3359,DB00588,10003549,442,16082,223,8245,0.868148113,1.016173508,0.861159256,1.201774245,0.941078569,DB0058810003549_,0.060728648,0.01604411,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,3360,DB00646,10003549,128,3325,64,1936,0.360447702,1.164513845,0.85123533,1.606327517,0.530331254,DB0064610003549_,0.634253461,0.1523037,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,3361,DB00889,10003549,82,698,47,470,0.448697993,1.174631204,0.794449859,1.752964395,0.616307993,DB0088910003549_,0.484008452,0.16095423,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,granisetron,DB00889
,3362,DB00905,10003549,40,2678,26,899,0.014311533,0.516538489,0.305614986,0.887031847,0.047431426,DB0090510003549_,3.048470272,-0.660605474,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,bimatoprost,DB00905
,3363,DB00996,10003549,1025,37928,598,21827,0.79396346,0.986404079,0.88965363,1.094431502,0.888340089,DB0099610003549_,0.118400626,-0.013689192,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,3364,DB06589,10003549,45,1985,72,2581,0.299593103,0.812693379,0.544520649,1.201726386,0.465592852,DB0658910003549_,0.764443735,-0.207401389,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pazopanib,DB06589
,3365,DB09153,10003549,162,7637,104,5595,0.316043205,1.141151744,0.884339153,1.477911053,0.483713998,DB0915310003549_,0.72626146,0.132038055,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,3366,DB14512,10003549,78,4766,49,2363,0.216559859,0.789286951,0.543166512,1.156521961,0.369362114,DB1451210003549_,0.995977778,-0.236625334,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,3380,DB00186,10003997,31,16870,23,9985,0.402190362,0.797768885,0.450044774,1.433582204,0.572008423,DB0018610003997_,0.558601563,-0.225936341,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,lorazepam,DB00186
,3393,DB00186,10010305,254,16647,214,9794,0.00016186,0.698336717,0.578829052,0.843048807,0.001203195,DB0018610010305_,6.722774504,-0.359053889,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,3394,DB00295,10010305,206,14457,188,9414,0.001044223,0.713545008,0.581659396,0.875746356,0.00571226,DB0029510010305_,5.165140603,-0.337509764,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,morphine,DB00295
,3395,DB00327,10010305,109,6029,100,4162,0.046481761,0.752491381,0.566603044,1.000214951,0.118463479,DB0032710010305_,2.133150559,-0.284365736,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,hydromorphone,DB00327
,3396,DB00557,10010305,92,5895,44,3023,0.784297182,1.072230772,0.738637988,1.577099748,0.882804532,DB0055710010305_,0.124651471,0.069741312,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,hydroxyzine,DB00557
,3397,DB00572,10010305,43,2859,27,2099,0.545303035,1.169184296,0.703606072,1.9745926,0.700089885,DB0057210010305_,0.356546544,0.156306323,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,atropine,DB00572
,3398,DB00588,10010305,162,16362,69,8399,0.209013179,1.205159446,0.902653867,1.623626484,0.36006284,DB0058810010305_,1.021476706,0.186611879,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,3399,DB00646,10010305,44,3409,23,1977,0.798841091,1.109436489,0.653329539,1.930901271,0.891356522,DB0064610010305_,0.115010795,0.103852218,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,nystatin,DB00646
,3402,DB00996,10010305,461,38492,333,22092,0.001607848,0.794566685,0.687879263,0.918513911,0.008129708,DB0099610010305_,4.812230323,-0.229958363,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,3404,DB09153,10010305,66,7733,67,5632,0.063639001,0.717465588,0.50194696,1.025227578,0.150029251,DB0915310010305_,1.896924997,-0.332030293,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,sodium chloride,DB09153
,3415,DB00996,10013578,32,38921,22,22403,0.572164168,0.837249644,0.471497829,1.512729821,0.722194297,DB0099610013578_,0.325461066,-0.177632993,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,3419,DB00186,10013971,88,16813,37,9971,0.094553785,1.410487002,0.949635277,2.132571755,0.202564108,DB0018610013971_,1.596698858,0.343935036,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,3420,DB00295,10013971,37,14626,24,9578,1,1.009577515,0.587626859,1.765142549,1,DB0029510013971_,0,0.009531942,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,3424,DB00588,10013971,129,16395,65,8403,0.939448426,1.017183111,0.748335052,1.394163466,0.978949994,DB0058810013971_,0.021274716,0.017037151,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,3428,DB00996,10013971,154,38799,63,22362,0.023613894,1.408860226,1.043870107,1.920995012,0.070329298,DB0099610013971_,2.654566816,0.342781027,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,3430,DB09153,10013971,38,7761,22,5677,0.432945134,1.263439707,0.727549432,2.245425192,0.601398486,DB0915310013971_,0.508497525,0.233837928,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,3432,DB00186,10016165,32,16869,42,9966,0.000672069,0.450132272,0.274834882,0.730811643,0.003961283,DB0018610016165_,5.531187359,-0.798213803,NA,10016165,Failure to thrive,10027433,Metabolism and nutrition disorders,Metab,lorazepam,DB00186
,3445,DB00186,10016256,1353,15548,593,9415,1.21535911377338e-10,1.381604024,1.249224205,1.529301348,3.89581881774797e-09,DB0018610016256_,19.36336196,0.32324516,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,3446,DB00557,10016256,350,5637,139,2928,0.00916901,1.307871419,1.065835953,1.611794502,0.033212627,DB0055710016256_,3.40482515,0.268400945,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,3447,DB00572,10016256,250,2652,183,1943,1,1.000894088,0.81626392,1.2290247,1,DB0057210016256_,0,0.000893689,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,atropine,DB00572
,3448,DB00588,10016256,1111,15413,496,7972,0.008217863,1.15856398,1.037576531,1.2949426,0.030438459,DB0058810016256_,3.492048363,0.14718129,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,3449,DB00646,10016256,258,3195,111,1889,0.006130095,1.374147279,1.087448639,1.745296637,0.024076804,DB0064610016256_,3.726506378,0.317833378,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,3450,DB00889,10016256,161,619,99,418,0.524578661,1.098075462,0.823485759,1.469066279,0.682702881,DB0088910016256_,0.381695534,0.093559067,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,granisetron,DB00889
,3451,DB00905,10016256,66,2652,43,882,0.00109097,0.51055458,0.339745414,0.774194693,0.005916877,DB0090510016256_,5.129946578,-0.672257733,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,bimatoprost,DB00905
,3452,DB06589,10016256,217,1813,295,2358,0.670712968,0.956717669,0.790648462,1.156440429,0.800240139,DB0658910016256_,0.222843423,-0.044246948,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pazopanib,DB06589
,3453,DB09153,10016256,422,7377,221,5478,3.48248940235706e-05,1.41791719,1.197432259,1.682562833,0.000323396,DB0915310016256_,8.036633022,0.349189027,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,3454,DB14512,10016256,214,4630,102,2310,0.760211315,1.046749868,0.818428265,1.345777951,0.866700271,DB1451210016256_,0.143062071,0.04569,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,3455,DB00186,10016807,93,16808,35,9973,0.021725226,1.576585751,1.057360512,2.398808498,0.065999758,DB0018610016807_,2.71810421,0.455261592,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,lorazepam,DB00186
,3456,DB00295,10016807,44,14619,44,9558,0.049351259,0.653837378,0.420250676,1.01725608,0.123807954,DB0029510016807_,2.089023671,-0.424896617,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,morphine,DB00295
,3460,DB00588,10016807,163,16361,66,8402,0.107099825,1.268318843,0.946019394,1.716957791,0.221767678,DB0058810016807_,1.50612494,0.237692278,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,fluticasone propionate,DB00588
,3464,DB00996,10016807,226,38727,110,22315,0.155657466,1.18388675,0.937925169,1.501594633,0.291642775,DB0099610016807_,1.232225599,0.168802881,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,3469,DB00295,10020646,18,14645,32,9570,0.000692736,0.367588661,0.194183227,0.675399716,0.00405536,DB0029510020646_,5.507715777,-1.000790736,male,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,morphine,DB00295
,3477,DB00996,10020646,70,38883,66,22359,0.004260982,0.609918073,0.429274895,0.867383014,0.01798762,DB0099610020646_,4.01807155,-0.494430637,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,3479,DB09153,10020646,34,7765,27,5672,0.795450411,0.919841309,0.538030441,1.587032425,0.889265654,DB0915310020646_,0.117359265,-0.083554115,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,sodium chloride,DB09153
,3481,DB00186,10038435,109,16792,85,9923,0.062142693,0.757813741,0.564773417,1.019635468,0.147440599,DB0018610038435_,1.914329901,-0.277317648,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,lorazepam,DB00186
,3482,DB00295,10038435,64,14599,58,9544,0.077773464,0.721397159,0.497202912,1.048532377,0.174582648,DB0029510038435_,1.745357024,-0.326565449,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,morphine,DB00295
,3483,DB00327,10038435,65,6073,39,4223,0.485006104,1.15890659,0.765895029,1.774318813,0.649146658,DB0032710038435_,0.432096612,0.147476966,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,hydromorphone,DB00327
,3484,DB00557,10038435,40,5947,26,3041,0.361662053,0.786734998,0.467419172,1.345464981,0.531460778,DB0055710038435_,0.632125878,-0.239863811,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,hydroxyzine,DB00557
,3485,DB00572,10038435,31,2871,25,2101,0.78594923,0.9074515,0.516823838,1.608193484,0.883823038,DB0057210038435_,0.12349842,-0.097115158,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,atropine,DB00572
,3486,DB00588,10038435,105,16419,61,8407,0.459136479,0.881370746,0.636105608,1.23043514,0.626498187,DB0058810038435_,0.467609399,-0.126276917,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,fluticasone propionate,DB00588
,3490,DB00996,10038435,245,38708,207,22218,5.5591824823103e-05,0.679391859,0.561859247,0.822089663,0.000483451,DB0099610038435_,7.634560272,-0.386557205,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,3492,DB09153,10038435,39,7760,37,5662,0.294530404,0.769101945,0.477094085,1.24179524,0.460392594,DB0915310038435_,0.775675689,-0.26253175,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,sodium chloride,DB09153
,3494,DB00186,10061428,375,16526,206,9802,0.409708199,1.079726618,0.906798533,1.288518363,0.57915943,DB0018610061428_,0.546177485,0.076707878,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,lorazepam,DB00186
,3495,DB00295,10061428,177,14486,169,9433,0.000471253,0.682034708,0.548335519,0.848525354,0.00293981,DB0029510061428_,5.82941025,-0.382674731,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,morphine,DB00295
,3496,DB00327,10061428,103,6035,75,4187,0.758938744,0.952829268,0.698802334,1.304175046,0.865568244,DB0032710061428_,0.144369058,-0.048319544,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,hydromorphone,DB00327
,3497,DB00557,10061428,85,5902,54,3013,0.240164344,0.803610035,0.562988328,1.155550742,0.398040277,DB0055710061428_,0.92120208,-0.218641159,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,hydroxyzine,DB00557
,3498,DB00572,10061428,83,2819,57,2069,0.729233157,1.068732147,0.749864149,1.532283335,0.842274653,DB0057210061428_,0.171649126,0.066473037,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,atropine,DB00572
,3499,DB00588,10061428,260,16264,149,8319,0.269277226,0.892554646,0.725627906,1.101119051,0.431806235,DB0058810061428_,0.839778322,-0.11366754,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,fluticasone propionate,DB00588
,3500,DB00646,10061428,71,3382,47,1953,0.499387227,0.87237336,0.592336279,1.295125178,0.661195983,DB0064610061428_,0.413704988,-0.136537781,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,nystatin,DB00646
,3501,DB00889,10061428,80,700,33,484,0.015779735,1.675554855,1.083938753,2.639759871,0.051301218,DB0088910061428_,2.97004079,0.516144367,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,granisetron,DB00889
,3503,DB00996,10061428,573,38380,332,22093,0.944557835,0.993495349,0.865441788,1.141938041,0.983216946,DB0099610061428_,0.016925486,-0.006525898,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,3504,DB06589,10061428,89,1941,140,2513,0.171644276,0.823089421,0.619564712,1.088884243,0.312960826,DB0658910061428_,1.161677252,-0.194690431,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,pazopanib,DB06589
,3505,DB09153,10061428,99,7700,65,5634,0.525248425,1.114442584,0.805208245,1.551225877,0.683354609,DB0915310061428_,0.380741361,0.108354355,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,sodium chloride,DB09153
,3506,DB14512,10061428,53,4791,21,2391,0.456789641,1.259452424,0.74488051,2.203651132,0.624163217,DB1451210061428_,0.471343379,0.230677043,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,mometasone furoate,DB14512
,3507,DB00186,10067973,30,16871,20,9988,0.663760127,0.888039645,0.487580583,1.650712238,0.795203843,DB0018610067973_,0.229156791,-0.118738892,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,lorazepam,DB00186
,3516,DB00996,10067973,30,38923,25,22400,0.206774183,0.690624825,0.392500931,1.224968624,0.357416855,DB0099610067973_,1.028852516,-0.370158548,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,gabapentin,DB00996
,3520,DB00051,10000087,231,25500,88,11332,0.246834941,1.166515539,0.907788808,1.510262808,0.405934833,DB0005110000087_,0.901562642,0.154021133,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,3522,DB00051,10019909,30,25701,31,11389,0.001202174,0.428846108,0.250642434,0.732794438,0.006413467,DB0005110019909_,5.049355319,-0.846657147,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,3523,DB00051,10037153,838,24893,455,10965,0.00052248,0.811295328,0.721289542,0.913380477,0.003201746,DB0005110037153_,5.744058963,-0.209123138,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,3524,DB00051,10040753,301,25430,87,11333,0.000311769,1.541846437,1.209450114,1.982654744,0.002082817,DB0005110040753_,6.174034209,0.432980683,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,adalimumab,DB00051
,3526,DB00126,10027599,67,10104,15,5930,0.000324753,2.621324156,1.480071776,4.946249644,0.002152596,DB0012610027599_,6.141080541,0.963679593,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,3527,DB00169,10027599,289,38402,44,18131,2.6588615869748e-15,3.101030445,2.251023055,4.363788664,1.69631497120467e-13,DB0016910027599_,29.40514797,1.131734458,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,3528,DB00537,10027599,60,7497,9,4289,2.35554286413802e-05,3.813636679,1.878334401,8.752831436,0.000229651,DB0053710027599_,8.378949134,1.338583243,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,3530,DB00005,10003983,201,127881,83,42336,0.098942797,0.801711669,0.617650339,1.048525628,0.209263173,DB0000510003983_,1.564162616,-0.221006251,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,3531,DB00005,10039203,258,127824,112,42307,0.018768258,0.762434116,0.608283746,0.960747688,0.058770985,DB0000510039203_,2.83410699,-0.27123918,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,3532,DB00005,10040753,3274,124808,750,41669,1.4020348248078e-21,1.45738718,1.34472891,1.5810878,1.72207875561089e-19,DB0000510040753_,43.20558463,0.37664523,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,etanercept,DB00005
,3533,DB00635,10003239,1390,31663,532,23262,3.32730766243206e-39,1.919507568,1.733227526,2.128298107,1.25839254542484e-36,DB0063510003239_,82.6632282,0.652068678,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,3534,DB00635,10019974,272,32781,108,23686,6.45532860408015e-08,1.819735896,1.450014152,2.297316989,1.21807833710156e-06,DB0063510019974_,13.61823607,0.598691378,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,prednisone,DB00635
,3535,DB00005,10037660,1619,126463,490,41929,0.080349434,1.095471984,0.98893237,1.215139941,0.179004523,DB0000510037660_,1.720344203,0.091185306,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,3536,DB00005,10048334,1956,126126,627,41792,0.491485315,1.033706813,0.943614519,1.13355477,0.654608133,DB0000510048334_,0.423718493,0.033151189,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,3537,DB00635,10048334,228,32825,68,23726,9.43874256188445e-12,2.423455119,1.839988204,3.227753913,3.6218590983815e-10,DB0063510048334_,21.73886347,0.885194257,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,3538,DB00005,10049187,162,127920,25,42394,0.000129972,2.14739013,1.403510637,3.416929353,0.000997186,DB0000510049187_,6.910573398,0.764253212,NA,10049187,Red blood cell sedimentation rate increased,10022891,Investigations,Inv,etanercept,DB00005
,3539,DB00635,10049187,51,33002,12,23782,0.000169073,3.062549844,1.610353006,6.312226642,0.001250799,DB0063510049187_,6.683973063,1.119247851,female,10049187,Red blood cell sedimentation rate increased,10022891,Investigations,Inv,prednisone,DB00635
,3540,DB00005,10057962,49,128033,19,42400,0.574917412,0.854083035,0.49366418,1.5363665,0.724521356,DB0000510057962_,0.322244041,-0.157726859,NA,10057962,Rheumatoid factor increased,10022891,Investigations,Inv,etanercept,DB00005
,3542,DB00005,10062519,85,127997,15,42404,0.02054279,1.877201634,1.076481834,3.500940934,0.06313191,DB0000510062519_,2.762528937,0.629782175,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,3543,DB00635,10062519,40,33013,20,23774,0.192674089,1.440270753,0.822096732,2.601193541,0.340002977,DB0063510062519_,1.078800907,0.364831119,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,3544,DB00005,10063743,68,128014,17,42402,0.379179375,1.324900934,0.76985149,2.405531922,0.549191639,DB0000510063743_,0.59930783,0.28133769,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,etanercept,DB00005
,3545,DB00635,10063743,75,32978,52,23742,0.857581897,1.038370677,0.719121408,1.509344906,0.931775585,DB0063510063743_,0.070663282,0.037652827,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,3546,DB00005,10000081,417,127665,115,42304,0.087561341,1.201560426,0.974905635,1.49066132,0.191087206,DB0000510000081_,1.655025379,0.183621067,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,3547,DB00795,10000081,54,4515,16,1487,0.781903494,1.111524916,0.62442935,2.087250846,0.881222599,DB0079510000081_,0.126445019,0.10573287,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,sulfasalazine,DB00795
,3548,DB00374,10064684,304,17412,82,5642,0.151738465,1.201265695,0.936511195,1.555456143,0.286372321,DB0037410064684_,1.250462492,0.183375747,NA,10064684,Device dislocation,10077536,Product issues,Prod,treprostinil,DB00374
,3549,DB00559,10064684,56,9603,20,3286,0.895043241,0.958117669,0.565025892,1.688399977,0.955980885,DB0055910064684_,0.04501736,-0.042784681,NA,10064684,Device dislocation,10077536,Product issues,Prod,bosentan,DB00559
,3550,DB00820,10064684,156,11759,31,5785,6.32343252623427e-07,2.475581874,1.672931116,3.772118672,9.54341387352716e-06,DB0082010064684_,11.55965929,0.906475469,NA,10064684,Device dislocation,10077536,Product issues,Prod,tadalafil,DB00820
,3551,DB00374,10011224,1234,16482,325,5399,0.000627862,1.243730468,1.095431928,1.415202166,0.003741411,DB0037410011224_,5.588292362,0.218115306,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,3552,DB00820,10011224,752,11163,209,5607,1.0038225912177e-14,1.807206649,1.542905049,2.123868591,5.90940130126704e-13,DB0082010011224_,28.15706169,0.591782366,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,3553,DB06403,10011224,831,20640,199,6462,0.000673681,1.3073628,1.115740429,1.537772952,0.003968556,DB0640310011224_,5.529352889,0.268011978,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,3557,DB00381,10006784,120,29240,77,22810,0.195478018,1.215728521,0.905120249,1.641277231,0.343642302,DB0038110006784_,1.068153982,0.195343503,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,3558,DB00404,10006784,129,19763,29,9833,4.16471827861439e-05,2.213170072,1.46895956,3.437714502,0.000377677,DB0040410006784_,7.881471759,0.79442591,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,3559,DB00641,10006784,65,14059,41,12434,0.097452052,1.402101435,0.933386647,2.127916286,0.207050655,DB0064110006784_,1.574791806,0.337972136,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,3560,DB00722,10006784,125,25278,86,25946,0.004580966,1.491878203,1.123985556,1.987980973,0.019040275,DB0072210006784_,3.961198783,0.400035865,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,3561,DB00788,10006784,47,9309,21,5040,0.525324154,1.211681713,0.709283502,2.136647393,0.683402394,DB0078810006784_,0.380671436,0.19200924,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,3562,DB00996,10006784,234,38719,105,22320,0.036229429,1.284693358,1.015594537,1.634063875,0.097987401,DB0099610006784_,2.322916373,0.250520058,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,3564,DB01175,10006784,50,10674,6,4886,0.000437408,3.813887579,1.633170273,10.89325623,0.002761445,DB0117510006784_,5.892001034,1.338649031,female,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,3565,DB00381,10013036,35,29325,20,22867,0.280077615,1.364602541,0.766003195,2.495300391,0.443926261,DB0038110013036_,0.81209681,0.310863207,NA,10013036,Diplopia,10015919,Eye disorders,Eye,amlodipine,DB00381
,3570,DB00996,10013036,78,38875,46,22379,0.925703882,0.976115073,0.669293402,1.438034165,0.968288692,DB0099610013036_,0.032225001,-0.024174796,NA,10013036,Diplopia,10015919,Eye disorders,Eye,gabapentin,DB00996
,3573,DB00381,10013573,1158,28202,671,22216,3.58491723233473e-10,1.359467522,1.233038335,1.499743468,1.07690913659335e-08,DB0038110013573_,18.34658572,0.307093095,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,3574,DB00641,10013573,514,13610,367,12108,0.001575689,1.245968806,1.085145511,1.431682107,0.008001908,DB0064110013573_,4.828075287,0.219913385,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,3575,DB00722,10013573,792,24611,771,25261,0.304271111,1.054389207,0.952129342,1.167629508,0.470927761,DB0072210013573_,0.753050571,0.052961649,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,3576,DB00788,10013573,330,9026,140,4921,0.014002908,1.285114691,1.048072962,1.582338019,0.046599536,DB0078810013573_,3.066164698,0.250847968,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,3577,DB01062,10013573,153,4333,59,1686,1,1.009040404,0.738351406,1.394293017,1,DB0106210013573_,0,0.008999784,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,3578,DB00381,10013700,1147,28213,457,22430,1.5154256881252e-37,1.995331505,1.786235058,2.231992194,5.34670660568737e-35,DB0038110013700_,78.91399747,0.690810205,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,amlodipine,DB00381
,3579,DB00404,10013700,497,19395,115,9747,1.6512548938175e-15,2.171849248,1.767035762,2.68786699,1.08372621433191e-13,DB0040410013700_,29.85320091,0.775578993,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,alprazolam,DB00404
,3580,DB00641,10013700,596,13528,284,12191,4.46606344134535e-19,1.891131562,1.635568852,2.190760815,4.26874463839136e-17,DB0064110013700_,37.69262679,0.63717536,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,simvastatin,DB00641
,3581,DB00722,10013700,1217,24186,566,25466,3.21754939841978e-60,2.263946495,2.044185077,2.509664618,2.72817051411174e-57,DB0072210013700_,130.2437191,0.817109527,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,lisinopril,DB00722
,3582,DB00788,10013700,753,8603,170,4891,1.31062152153266e-30,2.518070774,2.121058315,3.002980126,3.05529719426097e-28,DB0078810013700_,63.35550573,0.923493043,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,naproxen,DB00788
,3583,DB00996,10013700,3707,35246,1316,21109,2.62275924901957e-59,1.687019589,1.580063797,1.801995162,2.18854688445966e-56,DB0099610013700_,128.1615274,0.522963415,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,gabapentin,DB00996
,3584,DB01062,10013700,124,4362,22,1723,0.000252432,2.226140966,1.401114341,3.693534147,0.001750014,DB0106210013700_,6.348131298,0.800269578,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,oxybutynin,DB01062
,3585,DB01175,10013700,258,10466,69,4823,3.88594350933e-05,1.723032755,1.313254066,2.286395664,0.000356016,DB0117510013700_,7.940533859,0.544085968,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,escitalopram,DB01175
,3586,DB00381,10023232,347,29013,175,22712,1.57773397732217e-06,1.552207639,1.289461779,1.873977359,2.15488374091521e-05,DB0038110023232_,10.74518869,0.439678201,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,3587,DB00404,10023232,150,19742,34,9828,1.30371843035237e-05,2.196222426,1.503876658,3.290802459,0.000137073,DB0040410023232_,8.89499725,0.786738806,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,3588,DB00641,10023232,97,14027,60,12415,0.030294516,1.430854574,1.025527296,2.010419409,0.085317897,DB0064110023232_,2.461371039,0.35827187,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,3589,DB00722,10023232,209,25194,141,25891,0.000108171,1.523255086,1.223508138,1.901112354,0.000853065,DB0072210023232_,7.06667525,0.420849549,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,3590,DB00788,10023232,123,9233,35,5026,0.000545595,1.912929556,1.302494242,2.874991994,0.003317364,DB0078810023232_,5.70858491,0.648635866,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,3591,DB00996,10023232,299,38654,107,22318,1.32771775944766e-05,1.613410445,1.288743711,2.032660598,0.00013929,DB0099610023232_,8.878953848,0.478350227,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,3593,DB01175,10023232,70,10654,11,4881,0.000280562,2.915264736,1.531780791,6.112346434,0.001911748,DB0117510023232_,6.259737024,1.069960634,female,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,3594,DB00381,10030124,485,28875,309,22578,0.00548814,1.227283177,1.060742526,1.421600143,0.022035555,DB0038110030124_,3.815097995,0.204802927,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,3595,DB00404,10030124,209,19683,70,9792,0.003963353,1.485329986,1.126680385,1.978241668,0.016954467,DB0040410030124_,4.077223923,0.39563696,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,3596,DB00641,10030124,189,13935,153,12322,0.445301673,1.092269767,0.876667647,1.362750085,0.613309841,DB0064110030124_,0.48888502,0.088257886,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,3597,DB00722,10030124,288,25115,223,25809,0.001580621,1.327154883,1.109427667,1.589233128,0.008018262,DB0072210030124_,4.826033561,0.283037465,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,3598,DB00788,10030124,75,9281,42,5019,0.846379484,0.965714538,0.652209142,1.44684233,0.922855717,DB0078810030124_,0.080282377,-0.034886998,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,3599,DB00996,10030124,376,38577,202,22223,0.435060903,1.072292241,0.900624996,1.279694029,0.603492313,DB0099610030124_,0.505021977,0.069798638,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,3600,DB01062,10030124,40,4446,26,1719,0.052427546,0.594884975,0.352971138,1.018676173,0.129577627,DB0106210030124_,2.043475144,-0.519387211,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,3601,DB01175,10030124,80,10644,30,4862,0.40947437,1.218053551,0.790330795,1.922806096,0.578875589,DB0117510030124_,0.546667697,0.197254135,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,3607,DB00996,10040030,38,38915,20,22405,0.786685317,1.093919284,0.620557345,1.98474061,0.88426195,DB0099610040030_,0.123001937,0.08976692,NA,10040030,Sensory loss,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,3610,DB00381,10042674,285,29075,149,22738,6.48309519108082e-05,1.495846857,1.221740427,1.837591177,0.00054997,DB0038110042674_,7.505647105,0.402692506,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,3611,DB00404,10042674,130,19762,29,9833,3.11810262655654e-05,2.230438871,1.480935077,3.463604169,0.000293614,DB0040410042674_,8.133245577,0.802198369,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,3612,DB00641,10042674,108,14016,37,12438,1.52142805816622e-07,2.590079816,1.76652947,3.875063939,2.65895854447467e-06,DB0064110042674_,12.83757604,0.951688692,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,3613,DB00722,10042674,207,25196,123,25909,1.35084015716358e-06,1.73052002,1.376811076,2.182730518,1.87569115325118e-05,DB0072210042674_,10.88394826,0.548421953,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,3614,DB00788,10042674,95,9261,23,5038,0.000298525,2.246852792,1.410836263,3.718810403,0.002009662,DB0078810042674_,6.209788575,0.809530478,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,3615,DB00996,10042674,347,38606,130,22295,2.03132725302951e-05,1.541472406,1.255657611,1.901888825,0.00020244,DB0099610042674_,8.505069131,0.432738068,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,3617,DB01175,10042674,71,10653,9,4883,4.79612425541397e-05,3.615477383,1.799252394,8.237162341,0.000426331,DB0117510042674_,7.760294127,1.285223903,female,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,3618,DB00381,10047513,283,29077,142,22745,1.19277888388814e-05,1.558942368,1.268958474,1.922245822,0.00012665,DB0038110047513_,8.974083645,0.444007622,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,amlodipine,DB00381
,3619,DB00404,10047513,170,19722,49,9813,0.000523502,1.726221015,1.248315675,2.425583505,0.003206397,DB0040410047513_,5.742607425,0.545934635,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,alprazolam,DB00404
,3620,DB00641,10047513,131,13993,76,12399,0.003265532,1.52730355,1.141381086,2.055990552,0.014496623,DB0064110047513_,4.233839524,0.423503795,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,simvastatin,DB00641
,3621,DB00722,10047513,218,25185,170,25862,0.007971964,1.316812295,1.071748466,1.620173124,0.029705566,DB0072210047513_,3.51642083,0.275213888,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,lisinopril,DB00722
,3622,DB00788,10047513,84,9272,36,5025,0.250741757,1.264577883,0.844815422,1.927085041,0.410561707,DB0078810047513_,0.890229039,0.234738377,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,naproxen,DB00788
,3623,DB00996,10047513,344,38609,151,22274,0.004909949,1.314284145,1.081490341,1.60338216,0.020173195,DB0099610047513_,3.903400518,0.273292141,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,gabapentin,DB00996
,3624,DB01062,10047513,53,4433,19,1726,0.895006687,1.086073671,0.630310264,1.948578074,0.955976233,DB0106210047513_,0.045022227,0.082569056,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,oxybutynin,DB01062
,3625,DB01175,10047513,92,10632,28,4864,0.06060639,1.503134859,0.973848119,2.387468704,0.144539216,DB0117510047513_,1.934204414,0.407552833,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,escitalopram,DB01175
,3626,DB00264,10002855,386,29221,197,24695,5.36733156914759e-09,1.655883831,1.389993768,1.9776459,1.27964000267614e-07,DB0026410002855_,15.87151686,0.504334903,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,3627,DB01098,10002855,116,8033,58,7151,0.000307875,1.780334757,1.285910358,2.488256665,0.002061256,DB0109810002855_,6.18443966,0.576801413,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,rosuvastatin,DB01098
,3629,DB00264,10012378,362,29245,199,24693,9.03048350647201e-07,1.535936396,1.287314162,1.836875515,1.30924577478002e-05,DB0026410012378_,11.24347424,0.429140225,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,3630,DB01098,10012378,124,8025,74,7135,0.007855261,1.489794886,1.106106281,2.018441022,0.029347672,DB0109810012378_,3.528542061,0.39863845,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,rosuvastatin,DB01098
,3632,DB00264,10020772,514,29093,340,24552,0.000530524,1.275792685,1.109033243,1.468998639,0.003239049,DB0026410020772_,5.732475393,0.243567699,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,3633,DB01098,10020772,123,8026,94,7115,0.304306493,1.15997492,0.877822578,1.536926151,0.470968656,DB0109810020772_,0.752963735,0.148398384,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,rosuvastatin,DB01098
,3635,DB00264,10029223,55,29552,29,24863,0.047930133,1.595609398,0.999590056,2.596163603,0.121226226,DB0026410029223_,2.110096842,0.467255731,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,3638,DB00264,10044565,296,29311,206,24686,0.038343186,1.210159885,1.008726138,1.454031368,0.102325055,DB0026410044565_,2.279600714,0.190752487,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,3639,DB01098,10044565,76,8073,68,7141,1,0.988617959,0.702157108,1.394326529,1,DB0109810044565_,0,-0.011447312,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,3645,DB00398,10073071,17,710,51,1487,0.235828745,0.698225677,0.375230369,1.239845642,0.392972898,DB0039810073071_,0.934014632,-0.359212909,NA,10073071,Hepatocellular carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sorafenib,DB00398
,3686,DB00635,10025102,42,33011,42,23752,0.149931748,0.71953286,0.457645008,1.131248968,0.283828303,DB0063510025102_,1.259385791,-0.329153083,NA,10025102,Lung infiltration,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,3714,DB00635,10061354,22,33031,51,23743,2.00854186410964e-06,0.310080765,0.179021454,0.520718996,2.6569966229553e-05,DB0063510061354_,10.53572907,-1.170922484,male,10061354,Pneumonia fungal,10021881,Infections and infestations,Infec,prednisone,DB00635
,3718,DB00864,10061354,18,6851,37,8355,0.077253832,0.59330573,0.317666735,1.069983968,0.173675759,DB0086410061354_,1.750565172,-0.522045447,NA,10061354,Pneumonia fungal,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,3730,DB00188,10002034,161,7725,155,8673,0.190697072,1.166165942,0.927423515,1.466723378,0.337437984,DB0018810002034_,1.086373538,0.153721395,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,bortezomib,DB00188
,3731,DB00338,10002034,592,33082,440,21832,0.062696816,0.887917798,0.782565269,1.007990634,0.148480565,DB0033810002034_,1.907301201,-0.118876111,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,omeprazole,DB00338
,3732,DB00437,10002034,217,6704,263,11283,0.000477287,1.388589681,1.151734618,1.672843631,0.002972863,DB0043710002034_,5.818229655,0.328288614,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,allopurinol,DB00437
,3733,DB00480,10002034,993,66435,873,66789,0.004134431,1.143516046,1.042396178,1.254593907,0.017549132,DB0048010002034_,4.04275078,0.134107766,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,lenalidomide,DB00480
,3734,DB00787,10002034,302,16698,231,17017,0.001215611,1.332319058,1.117285818,1.590471421,0.006468084,DB0078710002034_,5.040875395,0.286921077,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,acyclovir,DB00787
,3735,DB00813,10002034,161,10411,90,10078,2.55694092990363e-05,1.731616141,1.327642631,2.270251924,0.000246111,DB0081310002034_,8.309728247,0.549055158,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,fentanyl,DB00813
,3736,DB00169,10011906,788,37903,800,17375,1.46291135226902e-53,0.451531027,0.408019134,0.499670701,9.85964740881822e-51,DB0016910011906_,115.1433893,-0.79511119,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,3737,DB00338,10011906,1203,32471,1169,21103,1.68151999848268e-21,0.668829375,0.615412044,0.726866137,2.05098622552748e-19,DB0033810011906_,43.030796,-0.402226297,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,3738,DB00437,10011906,406,6515,823,10723,0.000880487,0.811967701,0.716288687,0.919299506,0.004961472,DB0043710011906_,5.306052711,-0.208294716,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,3739,DB00531,10011906,336,6916,270,6246,0.169764303,1.123874631,0.951075301,1.329025591,0.310654455,DB0053110011906_,1.169074062,0.116782207,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,3740,DB00761,10011906,824,14483,622,8003,1.78964041814767e-08,0.732067855,0.656491172,0.816631845,3.79054781555291e-07,DB0076110011906_,14.7855851,-0.311882071,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,3741,DB00787,10011906,603,16397,871,16377,6.95211671356748e-12,0.691474529,0.620819171,0.769775427,2.74173125005433e-10,DB0078710011906_,22.01726137,-0.368928962,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,3742,DB00813,10011906,1001,9571,910,9258,0.203129103,1.064053227,0.967270585,1.170539657,0.352763271,DB0081310011906_,1.041958069,0.062085415,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,3743,DB01234,10011906,1872,29753,2168,30720,0.000445779,0.891534192,0.835908955,0.950823254,0.002807213,DB0123410011906_,5.875563053,-0.114811489,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,3744,DB00169,10038695,189,38502,146,18029,9.43090847049608e-06,0.606172486,0.485484966,0.758124364,0.000103288,DB0016910038695_,9.177988431,-0.500590702,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,3745,DB00188,10038695,33,7853,65,8763,0.008070106,0.566544034,0.360493573,0.875259664,0.029996851,DB0018810038695_,3.50666286,-0.568200472,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bortezomib,DB00188
,3746,DB00316,10038695,445,65029,338,36615,4.53350612006181e-05,0.741326474,0.641721682,0.856940061,0.000406423,DB0031610038695_,7.808116197,-0.299314165,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,3747,DB00338,10038695,231,33443,191,22081,0.024583778,0.798543216,0.655845633,0.973146076,0.072576472,DB0033810038695_,2.623114491,-0.224966191,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,3748,DB00437,10038695,93,6828,136,11410,0.336481839,1.14269707,0.866647499,1.501232845,0.505525715,DB0043710038695_,0.682156371,0.133391319,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,3749,DB00480,10038695,141,67287,198,67464,0.002288399,0.713999231,0.571012551,0.890860687,0.010858484,DB0048010038695_,4.522808577,-0.336873394,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,3750,DB00531,10038695,114,7138,135,6381,0.029416096,0.754908812,0.581722281,0.978254272,0.083413569,DB0053110038695_,2.483944287,-0.281158316,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclophosphamide,DB00531
,3751,DB00761,10038695,242,15065,145,8480,0.557451849,0.939454004,0.760164214,1.164352858,0.710533501,DB0076110038695_,0.341739181,-0.062456419,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,3752,DB00787,10038695,122,16878,150,17098,0.113929553,0.8239408,0.642778562,1.054425823,0.232061551,DB0078710038695_,1.460752635,-0.193656597,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,3753,DB00813,10038695,126,10446,129,10039,0.659179288,0.938662721,0.727330926,1.21127108,0.79180136,DB0081310038695_,0.233444727,-0.063299054,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,3754,DB01234,10038695,174,31451,303,32585,3.84877358788937e-08,0.594970802,0.490577069,0.719739637,7.60639201185504e-07,DB0123410038695_,14.0891067,-0.519242947,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,3757,DB00316,10040560,64,65410,45,36908,0.27272079,0.802512743,0.539475444,1.202743591,0.435627357,DB0031610040560_,0.830968086,-0.220007544,NA,10040560,Shock,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,3765,DB01234,10040560,37,31588,37,32851,0.907664181,1.039995402,0.641120539,1.687108324,0.958771936,DB0123410040560_,0.042102046,0.039216292,NA,10040560,Shock,10047065,Vascular disorders,Vasc,dexamethasone,DB01234
,3766,DB00169,10043554,196,38495,163,18012,1.06539297469066e-07,0.56266809,0.454400753,0.697446772,1.92202157445052e-06,DB0016910043554_,13.16213302,-0.575065364,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,3767,DB00188,10043554,118,7768,204,8624,0.000122763,0.642191098,0.50643954,0.811309984,0.000950763,DB0018810043554_,6.958245621,-0.442869358,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,bortezomib,DB00188
,3768,DB00316,10043554,426,65048,385,36568,2.54130158532521e-11,0.622010725,0.540351372,0.716264612,9.08817852656778e-10,DB0031610043554_,20.81887642,-0.474797944,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,3769,DB00338,10043554,186,33488,183,22089,0.000145835,0.670445368,0.543305984,0.82735969,0.001100252,DB0033810043554_,6.81221611,-0.39981306,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,omeprazole,DB00338
,3770,DB00437,10043554,85,6836,160,11386,0.388095501,0.884834269,0.670809055,1.160363761,0.558077042,DB0043710043554_,0.583258258,-0.122354918,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,allopurinol,DB00437
,3771,DB00531,10043554,180,7072,240,6276,4.53449421361555e-05,0.665608598,0.543874738,0.813396209,0.000406442,DB0053110043554_,7.808068784,-0.407053472,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,cyclophosphamide,DB00531
,3772,DB00761,10043554,156,15151,126,8499,0.002714975,0.694552353,0.544799734,0.886803829,0.0124591,DB0076110043554_,4.385303965,-0.364487737,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,potassium chloride,DB00761
,3773,DB00787,10043554,202,16798,245,17003,0.06323264,0.834557243,0.688390185,1.010847065,0.149352559,DB0078710043554_,1.901445603,-0.180853942,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,acyclovir,DB00787
,3774,DB00813,10043554,63,10509,49,10119,0.297272152,1.237985355,0.837869637,1.838578681,0.463190879,DB0081310043554_,0.769616045,0.213485344,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,fentanyl,DB00813
,3775,DB01234,10043554,380,31245,498,32390,0.000668988,0.791019417,0.689676326,0.906669772,0.003947547,DB0123410043554_,5.534660841,-0.234432764,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,dexamethasone,DB01234
,3776,DB00273,10000081,125,8356,17,2176,0.008848629,1.91465172,1.145982468,3.398809466,0.032274506,DB0027310000081_,3.433477659,0.649535736,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,topiramate,DB00273
,3780,DB00273,10012174,54,8427,16,2177,0.655830168,0.871872562,0.490420142,1.635503987,0.789436402,DB0027310012174_,0.236436003,-0.13711201,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,topiramate,DB00273
,3782,DB00273,10028813,520,7961,59,2134,1.24401998234384e-11,2.362505827,1.793691047,3.160826435,4.67797785921426e-10,DB0027310028813_,21.48298499,0.859722847,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,topiramate,DB00273
,3783,DB00953,10028813,141,1556,25,207,0.212075066,0.750431451,0.474257379,1.228623894,0.363863781,DB0095310028813_,1.01097571,-0.28710697,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,rizatriptan,DB00953
,3786,DB00273,10047700,263,8218,38,2155,0.000369648,1.814768721,1.283178296,2.630943712,0.002401338,DB0027310047700_,6.031729248,0.595958033,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,topiramate,DB00273
,3787,DB00953,10047700,64,1633,8,224,1,1.097339457,0.515562869,2.685896486,1,DB0095310047700_,0,0.092888574,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,rizatriptan,DB00953
,3792,DB01060,10025197,38,8549,19,5062,0.585586725,1.184254931,0.665128744,2.177230235,0.733042313,DB0106010025197_,0.310551854,0.169113826,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,amoxicillin,DB01060
,3798,DB01060,10073508,40,8547,28,5053,0.52994367,0.844591033,0.507532249,1.42336717,0.687116507,DB0106010073508_,0.375251414,-0.168902754,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,amoxicillin,DB01060
,3799,DB01137,10033425,169,7603,90,5503,0.021866368,1.359091315,1.043632839,1.779663014,0.066311794,DB0113710033425_,2.713387503,0.306816325,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,3800,DB09053,10033425,37,2248,47,4005,0.137066937,1.402394588,0.883390259,2.211888718,0.26559561,DB0905310033425_,1.32578039,0.338181196,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ibrutinib,DB09053
,3801,DB00264,10003658,668,28939,715,24177,5.56046318983257e-06,0.780537441,0.700360179,0.869792851,6.48576769224536e-05,DB0026410003658_,9.643315275,-0.24777257,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,metoprolol,DB00264
,3802,DB00437,10003658,113,6808,212,11334,0.325967184,0.887360712,0.698482235,1.122522746,0.494473582,DB0043710003658_,0.704261554,-0.119503714,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,allopurinol,DB00437
,3804,DB00678,10003658,180,15419,159,10565,0.022444053,0.775707575,0.622245309,0.967712728,0.067607372,DB0067810003658_,2.694038253,-0.253979666,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,losartan,DB00678
,3805,DB00695,10003658,543,27506,487,20041,0.001020896,0.812395435,0.716512274,0.921267845,0.005599804,DB0069510003658_,5.185023664,-0.207768069,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,furosemide,DB00695
,3806,DB00727,10003658,70,3773,103,4070,0.054162225,0.733138971,0.531478169,1.006349545,0.132760207,DB0072710003658_,2.019210736,-0.310420002,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,nitroglycerin,DB00727
,3807,DB00758,10003658,122,8178,136,9938,0.528812051,1.090110573,0.845115901,1.404877408,0.686168703,DB0075810003658_,0.376631759,0.086279134,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,3808,DB00924,10003658,55,10107,49,4202,0.000140382,0.466677017,0.311155432,0.701675937,0.001065839,DB0092410003658_,6.843992867,-0.762117872,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,cyclobenzaprine,DB00924
,3809,DB00973,10003658,39,3812,49,2972,0.030248993,0.620586424,0.395632486,0.967581819,0.085232866,DB0097310003658_,2.462368167,-0.477090403,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ezetimibe,DB00973
,3811,DB14500,10003658,117,7692,75,3998,0.167771085,0.810856864,0.600014275,1.101403954,0.307876075,DB1450010003658_,1.178057932,-0.209663734,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,potassium,DB14500
,3824,DB00193,10010305,199,19121,145,8557,1.32053379091727e-05,0.614191364,0.492602512,0.767307527,0.000138619,DB0019310010305_,8.883780442,-0.487448732,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,3825,DB00213,10010305,214,18681,163,13258,0.52822498,0.93176249,0.755461512,1.150941874,0.685665996,DB0021310010305_,0.377364656,-0.070677336,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,3826,DB00264,10010305,307,29300,319,24573,0.007737651,0.80712671,0.687136051,0.947951385,0.029012171,DB0026410010305_,3.540039837,-0.21427461,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,3827,DB00437,10010305,86,6835,145,11401,1,0.989316001,0.747378411,1.302968439,1,DB0043710010305_,0,-0.010741483,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,allopurinol,DB00437
,3829,DB00678,10010305,146,15453,105,10619,0.747045134,0.955538047,0.737516272,1.241465469,0.856012962,DB0067810010305_,0.15546976,-0.045480697,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,losartan,DB00678
,3830,DB00695,10010305,353,27696,235,20293,0.274847165,1.100641666,0.929581235,1.304988147,0.438078815,DB0069510010305_,0.825356442,0.095893343,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,3831,DB00727,10010305,51,3792,62,4111,0.570405298,0.891796935,0.601663757,1.316691534,0.720960612,DB0072710010305_,0.327170772,-0.114516823,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,nitroglycerin,DB00727
,3832,DB00758,10010305,100,8200,127,9947,0.78845896,0.955150251,0.726262149,1.253343898,0.885444006,DB0075810010305_,0.121666058,-0.04588662,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,clopidogrel,DB00758
,3833,DB00924,10010305,131,10031,57,4194,0.809349331,0.960906428,0.697330242,1.338463415,0.897266799,DB0092410010305_,0.108402026,-0.039878244,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,3834,DB00973,10010305,39,3812,36,2985,0.485149758,0.8483309,0.523895149,1.377106195,0.649262328,DB0097310010305_,0.43191844,-0.164484507,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ezetimibe,DB00973
,3836,DB14500,10010305,101,7708,44,4029,0.334020539,1.199798118,0.832289683,1.754512089,0.50306431,DB1450010010305_,0.687037264,0.182153308,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,potassium,DB14500
,3837,DB00193,10024378,34,19286,18,8684,0.55261323,0.850537482,0.466725339,1.600633902,0.706404316,DB0019310024378_,0.347567519,-0.161886797,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,tramadol,DB00193
,3838,DB00213,10024378,38,18857,27,13394,1,0.999667089,0.594185088,1.703524247,1,DB0021310024378_,0,-0.000332967,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,pantoprazole,DB00213
,3839,DB00264,10024378,44,29563,56,24836,0.04410305,0.660094267,0.434209584,0.997844047,0.113782577,DB0026410024378_,2.173465869,-0.415372625,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,metoprolol,DB00264
,3840,DB00437,10024378,18,6903,36,11510,0.575747507,0.833673346,0.445324921,1.508420688,0.725180897,DB0043710024378_,0.321334142,-0.181913624,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,allopurinol,DB00437
,3843,DB00695,10024378,69,27980,58,20470,0.472028563,0.870349218,0.604618947,1.256706616,0.638119205,DB0069510024378_,0.449230171,-0.138860747,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,furosemide,DB00695
,3864,DB00213,10063743,59,18836,37,13384,0.604594174,1.13308044,0.738262164,1.759276847,0.747842343,DB0021310063743_,0.290563095,0.124939977,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,3865,DB00264,10063743,71,29536,53,24839,0.528819419,1.126565478,0.777906748,1.640346524,0.686168703,DB0026410063743_,0.376631759,0.119173604,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,3869,DB00695,10063743,86,27963,66,20462,0.805301627,0.953526743,0.683486045,1.335392551,0.894590507,DB0069510063743_,0.1113892,-0.047587807,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,3879,DB00273,10020772,93,8388,20,2173,0.558004363,1.204609648,0.735192188,2.067250748,0.710996397,DB0027310020772_,0.341087917,0.186155571,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,topiramate,DB00273
,3881,DB00722,10020772,533,24870,417,25615,3.11821442760419e-05,1.316454345,1.154528309,1.50191375,0.000293614,DB0072210020772_,8.133245577,0.27494202,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,lisinopril,DB00722
,3891,DB00016,10062355,32,2730,38,2252,0.146892156,0.69471756,0.418677093,1.146118107,0.279635003,DB0001610062355_,1.274270086,-0.364249905,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,3892,DB00181,10028334,359,9497,325,5546,2.80207299131108e-08,0.645113069,0.551570381,0.754693779,5.68745085533682e-07,DB0018110028334_,14.37983351,-0.438329676,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,3893,DB00213,10028334,294,18601,181,13240,0.133405474,1.156132793,0.956116887,1.40111383,0.260536659,DB0021310028334_,1.345011702,0.145080636,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,3894,DB00230,10028334,406,19268,133,8518,0.002505455,1.349543972,1.104917015,1.656855845,0.011679682,DB0023010028334_,4.449904557,0.299766737,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,3895,DB00295,10028334,133,14530,109,9493,0.085836513,0.797208481,0.613321788,1.038036912,0.188088261,DB0029510028334_,1.670843953,-0.226639052,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,3899,DB00490,10028334,65,4005,24,1552,0.905572397,1.049499242,0.645431599,1.759786296,0.957861963,DB0049010028334_,0.0430516,0.048313138,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,buspirone,DB00490
,3900,DB00641,10028334,242,13882,159,12316,0.003427996,1.350299401,1.09919558,1.662506412,0.015073322,DB0064110028334_,4.194828847,0.300326346,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,3901,DB00695,10028334,435,27614,218,20310,3.51679627454955e-06,1.467606082,1.24310623,1.736644987,4.34189713839995e-05,DB0069510028334_,10.04461408,0.383632558,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,3902,DB00706,10028334,14,1061,211,15714,1,0.982691819,0.526246183,1.693563719,1,DB0070610028334_,0,-0.017459718,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,tamsulosin,DB00706
,3903,DB00737,10028334,56,2745,14,918,0.403171307,1.337587851,0.730615996,2.614774814,0.572931978,DB0073710028334_,0.556988282,0.290867881,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,meclizine,DB00737
,3904,DB00761,10028334,264,15043,107,8518,0.003813344,1.397067859,1.110035119,1.768583819,0.016410241,DB0076110028334_,4.109849666,0.334375654,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,3905,DB00863,10028334,190,10483,66,5774,0.001202032,1.585584787,1.189996954,2.135308787,0.006413467,DB0086310028334_,5.049355319,0.46095329,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,3906,DB00956,10028334,105,5709,40,3427,0.015177963,1.575662546,1.082076667,2.334514408,0.049775766,DB0095610028334_,3.000227043,0.454675848,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocodone,DB00956
,3908,DB01062,10028334,63,4423,29,1716,0.482726645,0.84288094,0.532745568,1.36239767,0.647024291,DB0106210028334_,0.435371441,-0.170929564,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,oxybutynin,DB01062
,3909,DB01069,10028334,109,6591,38,2357,1,1.025782616,0.700811179,1.530442811,1,DB0106910028334_,0,0.025455849,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,promethazine,DB01069
,3910,DB01104,10028334,181,15282,73,7213,0.279459008,1.170264388,0.885699997,1.559919452,0.443305975,DB0110410028334_,0.813495058,0.157229696,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,3913,DB11089,10028334,159,10016,124,8283,0.673661836,1.060409784,0.831605636,1.354672198,0.802138219,DB1108910028334_,0.220474343,0.058655423,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,3914,DB14512,10067482,838,4006,526,1886,4.99183620524684e-06,0.750105871,0.662849386,0.849223349,5.91304257119933e-05,DB1451210067482_,9.735764949,-0.287540921,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,3915,DB14512,10069327,1219,3625,626,1786,0.474426791,0.959431765,0.85676476,1.074916519,0.640077413,DB1451210069327_,0.446166152,-0.041414081,NA,10069327,Product quality issue,10077536,Product issues,Prod,mometasone furoate,DB14512
,3927,DB01012,10040047,32,10600,30,8655,0.610655139,0.870951073,0.512107431,1.485005191,0.752793844,DB0101210040047_,0.283963869,-0.138169477,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,cinacalcet,DB01012
,3930,DB00480,10061024,494,66934,749,66913,5.80384090015963e-13,0.659344826,0.587029141,0.740045106,2.67873499667596e-11,DB0048010061024_,24.34309136,-0.416508624,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,3938,DB06703,10047700,128,647,98,313,0.003087604,0.632096476,0.465489336,0.859888655,0.013849431,DB0670310047700_,4.279511095,-0.458713244,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,gadobutrol,DB06703
,3939,DB09140,10047700,226,3515,64,1734,7.96543226476064e-05,1.74185763,1.305825785,2.350886236,0.000656645,DB0914010047700_,7.328366405,0.554952147,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,oxygen,DB09140
,3940,DB00068,10012378,100,2134,30,635,1,0.991880193,0.646751614,1.56096429,1,DB0006810012378_,0,-0.008152952,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,interferon beta-1b,DB00068
,3941,DB00068,10033371,114,2120,35,630,0.841993506,0.967933589,0.649942731,1.472735611,0.919495598,DB0006810033371_,0.083930022,-0.032591801,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,3956,DB00316,10007632,66,65408,39,36914,0.839157179,0.955092265,0.633233848,1.457903718,0.917579984,DB0031610007632_,0.086015527,-0.045947331,NA,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,3961,DB00316,10043089,67,65407,58,36895,0.01950543,0.651586137,0.451513355,0.9428758,0.060635116,DB0031610043089_,2.802881078,-0.428345678,NA,10043089,Tachypnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,3963,DB00316,10044640,37,65437,19,36934,0.78247423,1.099145495,0.615989824,2.023685643,0.881639846,DB0031610044640_,0.125971644,0.094533056,NA,10044640,Tricuspid valve incompetence,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,3973,DB00316,10071404,85,65389,67,36886,0.042558585,0.715678191,0.513329888,1.001242949,0.110828346,DB0031610071404_,2.199772703,-0.334524667,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,3975,DB00316,10033645,171,65303,125,36828,0.029091452,0.771511129,0.608783872,0.97993238,0.082702663,DB0031610033645_,2.492503479,-0.259404182,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,3976,DB08882,10033645,52,945,70,923,0.093018919,0.725683381,0.490977811,1.066943298,0.200122961,DB0888210033645_,1.608823294,-0.320641473,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,linagliptin,DB08882
,3979,DB00005,10003986,61,128021,32,42387,0.040733127,0.631150376,0.404919663,1.000842482,0.10710451,DB0000510003986_,2.233950189,-0.460211131,NA,10003986,Back injury,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,3980,DB00005,10003988,2098,125984,764,41655,0.024702454,0.907944164,0.834767378,0.988382368,0.072853184,DB0000510003988_,2.61930904,-0.096572396,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,3981,DB00005,10029223,156,127926,54,42365,0.810625406,0.956704703,0.697731708,1.32939487,0.89818901,DB0000510029223_,0.107374754,-0.0442605,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,3982,DB00005,10049088,88,127994,8,42411,4.76057296408342e-05,3.6449506,1.770774145,8.706466582,0.000423601,DB0000510049088_,7.766719183,1.293342813,female,10049088,Osteopenia,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,3983,DB00005,10050296,219,127863,88,42331,0.128631485,0.82388192,0.640347794,1.067816448,0.253672851,DB0000510050296_,1.371709831,-0.19372806,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,3985,DB00921,10010305,44,5801,40,4863,0.742160822,0.922142447,0.586096774,1.454689182,0.852236662,DB0092110010305_,0.159891018,-0.081055569,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,3986,DB00005,10022998,102,127980,39,42380,0.43661876,0.866094573,0.593282975,1.287116227,0.605190187,DB0000510022998_,0.502212512,-0.14376117,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,3987,DB00005,10028334,833,127249,251,42168,0.192379111,1.099763652,0.953448624,1.272116848,0.339620384,DB0000510028334_,1.079926803,0.095095295,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,3988,DB00005,10062556,374,127708,92,42327,0.009933386,1.347338833,1.069563542,1.712022365,0.035369689,DB0000510062556_,3.341900059,0.298131412,NA,10062556,Grip strength decreased,10022891,Investigations,Inv,etanercept,DB00005
,3989,DB00005,10061194,299,127783,50,42369,1.61642828687325e-06,1.982664993,1.465419628,2.732033572,2.2014413223038e-05,DB0000510061194_,10.72381317,0.684441896,NA,10061194,Hand deformity,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,3992,DB00005,10020772,525,127557,153,42266,0.167825231,1.13698236,0.947533628,1.370881683,0.30793551,DB0000510020772_,1.177864901,0.1283777,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,etanercept,DB00005
,3994,DB06228,10051055,437,15475,577,15499,1.85098818365715e-05,0.758549419,0.667001437,0.862197491,0.000186688,DB0622810051055_,8.586071128,-0.276347328,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,rivaroxaban,DB06228
,3995,DB06228,10066901,49,15863,73,16003,0.036820184,0.677168368,0.461302935,0.986561532,0.099219171,DB0622810066901_,2.31042403,-0.38983534,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,3996,DB00338,10013709,1384,32290,834,21438,0.030101398,1.101779404,1.008528163,1.204123192,0.084921675,DB0033810013709_,2.466025921,0.096926513,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,3997,DB01175,10013709,570,10154,228,4664,0.091996404,1.148295732,0.979132809,1.350213228,0.198432605,DB0117510013709_,1.617305759,0.138278871,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,3998,DB00338,10067482,102,33572,61,22211,0.575194653,1.106289663,0.797388225,1.545970369,0.7246849,DB0033810067482_,0.322018339,0.10101177,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,3999,DB01175,10067482,43,10681,23,4869,0.594831586,0.85227437,0.50168533,1.483335461,0.74054655,DB0117510067482_,0.300366784,-0.159846774,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,4005,DB00563,10022052,510,46136,84,15264,2.21126184631768e-10,2.008815396,1.590707688,2.563258726,6.8339820847102e-09,DB0056310022052_,18.8013583,0.697545193,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,4006,DB00563,10022061,858,45788,83,15265,1.57187233716008e-36,3.446400733,2.746221495,4.37459577,5.26326934805767e-34,DB0056310022061_,76.62714078,1.237330421,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,4007,DB00563,10022093,557,46089,43,15305,1.7637863933291e-29,4.301565612,3.149571056,6.013862509,3.76919718281752e-27,DB0056310022093_,60.84293548,1.458979052,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,4008,DB00563,10022107,165,46481,13,15335,2.63325248513785e-09,4.187472076,2.381182475,8.03401627,6.73298069765063e-08,DB0056310022107_,16.5136628,1.432097229,female,10022107,Injection site urticaria,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,4009,DB00563,10029223,43,46603,17,15331,0.549357516,0.832079865,0.464648081,1.55671202,0.703696994,DB0056310029223_,0.351407422,-0.183826851,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,4010,DB00005,10040844,358,127724,189,42230,3.96010521946979e-07,0.626284034,0.523449833,0.751273335,6.26678902430846e-06,DB0000510040844_,11.98024645,-0.467951283,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,4011,DB00563,10040844,74,46572,30,15318,0.362586016,0.811301878,0.524015956,1.285358662,0.53220767,DB0056310040844_,0.630721509,-0.209115064,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,4012,DB00563,10053425,538,46108,62,15286,3.34219997964736e-19,2.876891747,2.207119324,3.807094533,3.22976935533202e-17,DB0056310053425_,37.97153585,1.056710457,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,4013,DB00480,10007882,321,67107,301,67361,0.399027481,1.070514318,0.91147452,1.257480455,0.568910354,DB0048010007882_,0.564032407,0.068139204,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,4014,DB01234,10007882,203,31422,200,32688,0.617277629,1.055917403,0.863735238,1.290875567,0.758352821,DB0123410007882_,0.276606538,0.054409966,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,4017,DB00005,10013968,1429,126653,392,42027,0.000798316,1.209641094,1.080378829,1.356885625,0.004566643,DB0000510013968_,5.388976876,0.190323699,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,4018,DB00005,10016338,58,128024,19,42400,1,1.010996425,0.593264833,1.797868331,1,DB0000510016338_,0,0.010936404,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,4030,DB00264,10037884,116,29491,91,24801,0.625557358,1.072023952,0.807219303,1.427265246,0.765189527,DB0026410037884_,0.267631728,0.069548406,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,4032,DB00316,10037884,228,65246,98,36855,0.024198625,1.314169324,1.032330179,1.683327476,0.071689024,DB0031610037884_,2.63541763,0.273204774,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,4033,DB00381,10037884,127,29233,83,22804,0.236094786,1.19360776,0.89755568,1.594541621,0.393354131,DB0038110037884_,0.933044976,0.176980452,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,4035,DB00924,10037884,38,10124,16,4235,1,0.99349358,0.54022304,1.910695881,1,DB0092410037884_,0,-0.006527679,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,cyclobenzaprine,DB00924
,4037,DB01098,10037884,34,8115,19,7190,0.12887022,1.585446354,0.878144926,2.945154808,0.253962644,DB0109810037884_,1.370568094,0.460865979,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,rosuvastatin,DB01098
,4039,DB06228,10037884,55,15857,43,16033,0.22512439,1.293252323,0.851479151,1.975670281,0.379977819,DB0622810037884_,0.967642398,0.257160226,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,rivaroxaban,DB06228
,4040,DB06724,10037884,46,7883,13,3906,0.072601222,1.753221027,0.929993082,3.541618329,0.165840195,DB0672410037884_,1.796730635,0.561454683,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,calcium carbonate,DB06724
,4062,DB00005,10011906,404,127678,306,42113,2.72492541624464e-26,0.435470269,0.374278071,0.507092248,4.6060877534399e-24,DB0000510011906_,53.73466338,-0.831328753,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,4063,DB00065,10028411,52,9412,32,4925,0.490153179,0.850329376,0.536361905,1.3669803,0.653479563,DB0006510028411_,0.42544402,-0.162131503,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,infliximab,DB00065
,4065,DB01098,10028411,235,7914,250,6959,0.041865262,0.826580663,0.68669577,0.994677318,0.109453648,DB0109810028411_,2.212254121,-0.190457771,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,4066,DB01104,10028411,158,15305,60,7226,0.165847263,1.243242614,0.916749876,1.705132579,0.305294159,DB0110410028411_,1.186479511,0.217722978,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,4067,DB00065,10050551,90,9374,26,4931,0.005874134,1.820802555,1.163962934,2.939987184,0.023281306,DB0006510050551_,3.760104549,0.599277368,NA,10050551,Lupus-like syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,infliximab,DB00065
,4071,DB00188,10070863,225,7661,328,8500,0.002076752,0.761114717,0.637597113,0.90727439,0.010032611,DB0018810070863_,4.601914412,-0.272971188,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,bortezomib,DB00188
,4073,DB00404,10055798,59,19833,36,9826,0.327296315,0.811989359,0.527164316,1.266353221,0.495720629,DB0040410055798_,0.70174276,-0.208268043,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,alprazolam,DB00404
,4076,DB00996,10055798,107,38846,87,22338,0.020360335,0.707261802,0.527701115,0.950094454,0.062673781,DB0099610055798_,2.769812087,-0.346354382,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,gabapentin,DB00996
,4079,DB00060,10041466,59,9449,20,2445,0.327388253,0.763353603,0.451949265,1.341198895,0.495817022,DB0006010041466_,0.701548328,-0.270033917,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,4080,DB00060,10048334,147,9361,55,2410,0.022260262,0.688120981,0.499800516,0.959149799,0.067217791,DB0006010048334_,2.699817321,-0.373790613,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,4081,DB00060,10061623,172,9336,54,2411,0.213343772,0.822580825,0.600479455,1.142406625,0.365456095,DB0006010061623_,1.006609131,-0.195308534,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,4082,DB00005,10023424,268,127814,27,42392,7.51211545098713e-12,3.29222428,2.211856433,5.08993232,2.92961357016612e-10,DB0000510023424_,21.9509804,1.191563409,female,10023424,Kidney infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,4083,DB00318,10013700,2688,1595,327,1512,1.2777925747084e-242,7.788637677,6.799367781,8.942393774,1.34347111304841e-238,DB0031810013700_,547.7199955,2.052665964,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,codeine,DB00318
,4084,DB00331,10013700,658,24288,264,20488,6.56938578726685e-26,2.102385812,1.81762662,2.437595475,1.07586483126672e-23,DB0033110013700_,52.88633231,0.743072801,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,metformin,DB00331
,4085,DB00472,10013700,311,10448,66,4246,5.94855305669164e-07,1.914904496,1.460179911,2.543235126,9.03540693990983e-06,DB0047210013700_,11.61435959,0.64966775,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,fluoxetine,DB00472
,4086,DB01118,10013700,120,2943,109,4600,6.29937955434747e-05,1.720582359,1.310754158,2.260856572,0.000536898,DB0111810013700_,7.529703341,0.542662814,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,amiodarone,DB01118
,4087,DB01156,10013700,475,13147,91,6237,1.02768118655543e-17,2.476194269,1.97064795,3.140494569,8.54829113563593e-16,DB0115610013700_,34.69563009,0.906722813,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,bupropion,DB01156
,4088,DB00005,10013700,2755,125327,408,42011,1.68177963380802e-63,2.263592982,2.037978194,2.519139312,1.60747555180523e-60,DB0000510013700_,137.6804406,0.816953366,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,etanercept,DB00005
,4089,DB00563,10013700,4063,42583,700,14648,1.88000020459804e-69,1.996579801,1.838110162,2.171101086,2.14851327729824e-66,DB0056310013700_,151.20584,0.691435617,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,methotrexate,DB00563
,4090,DB00005,10060795,506,127576,195,42224,0.072749947,0.858852827,0.726347571,1.018781171,0.166114959,DB0000510060795_,1.795075204,-0.152157702,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,etanercept,DB00005
,4091,DB00005,10014020,276,127806,29,42390,1.10291142809437e-11,3.156728946,2.148617192,4.80341177,4.18628547111344e-10,DB0000510014020_,21.59403711,1.149536348,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,etanercept,DB00005
,4092,DB00005,10047340,224,127858,43,42376,0.000645585,1.726442134,1.240984213,2.452442653,0.003830509,DB0000510047340_,5.564757596,0.546062721,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,etanercept,DB00005
,4093,DB00005,10003549,1192,126890,392,42027,0.930206301,1.007143873,0.897264967,1.132386162,0.971490489,DB0000510003549_,0.0289238,0.007118476,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,4094,DB00005,10020765,103,127979,33,42386,0.92121754,1.033746399,0.692304467,1.580276198,0.965093784,DB0000510020765_,0.035529997,0.033189484,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,4095,DB00005,10024855,225,127857,57,42362,0.073026952,1.307840001,0.973886254,1.781562625,0.166573822,DB0000510024855_,1.79231669,0.268376922,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,4097,DB00169,10037377,240,38451,172,18003,3.31347611252749e-05,0.653308169,0.534445836,0.799971886,0.00030967,DB0016910037377_,8.080002975,-0.425706332,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,4098,DB00264,10037377,226,29381,204,24688,0.466337429,0.93090274,0.766303798,1.131363144,0.633093464,DB0026410037377_,0.457137215,-0.071600475,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,4099,DB00285,10037377,57,10894,22,3696,0.604842,0.879039133,0.528178746,1.512289973,0.748052492,DB0028510037377_,0.290282127,-0.128925863,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,venlafaxine,DB00285
,4101,DB00695,10037377,197,27852,179,20349,0.036111521,0.804090342,0.652852164,0.99086927,0.097748965,DB0069510037377_,2.325352665,-0.218043651,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,4102,DB00761,10037377,157,15150,90,8535,0.894180576,0.982754341,0.752556236,1.289872722,0.955860142,DB0076110037377_,0.045143671,-0.017396098,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,4104,DB00996,10037377,213,38740,191,22234,9.83039926245211e-06,0.640070172,0.523618965,0.782776584,0.000107005,DB0099610037377_,9.142637961,-0.446177465,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,4105,DB01104,10037377,85,15378,37,7249,0.770498793,1.082912303,0.727135369,1.640923543,0.874236414,DB0110410037377_,0.134404443,0.079653988,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,4107,DB00497,10013700,939,18328,287,16088,7.25090410349755e-62,2.871640151,2.50901722,3.295039306,6.57206946070459e-59,DB0049710013700_,133.9696917,1.054883348,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,oxycodone,DB00497
,4108,DB01142,10013700,108,1632,7,777,3.70718087928546e-11,7.342434429,3.421466279,18.78054135,1.29837774033335e-09,DB0114210013700_,20.46215024,1.993670454,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,doxepin,DB01142
,4109,DB00497,10019063,99,19168,75,16300,0.49272093,1.12247222,0.822504106,1.537330972,0.655556268,DB0049710019063_,0.422271139,0.115533592,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,4114,DB00451,10013946,398,46873,79,15340,2.3603573603201e-05,1.648691312,1.291260136,2.128046675,0.000229955,DB0045110013946_,8.377624757,0.499981829,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,4117,DB00451,10013971,233,47038,67,15352,0.382905141,1.13499973,0.860947598,1.513525252,0.552980733,DB0045110013971_,0.592432119,0.126632413,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,4120,DB00451,10017853,86,47185,22,15397,0.370720714,1.275566456,0.790839573,2.14122049,0.54042093,DB0045110017853_,0.615406943,0.243390359,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,4134,DB00451,10027599,365,46906,41,15378,1.51321366483148e-13,2.918727443,2.108309037,4.138202836,7.56894789345298e-12,DB0045110027599_,25.60696704,1.071147714,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,4143,DB00451,10053762,1428,45843,417,15002,0.04514665,1.120642016,1.002488159,1.254792661,0.115867381,DB0045110053762_,2.155309008,0.11390175,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,4144,DB00783,10053762,639,16075,23,350,0.02861608,0.604934701,0.393146688,0.97416923,0.081650994,DB0078310053762_,2.505301283,-0.502634759,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,estradiol,DB00783
,4146,DB00451,10061224,143,47128,29,15390,0.016661642,1.610203806,1.073942635,2.491672166,0.053532729,DB0045110061224_,2.927462062,0.476360758,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,4164,DB00404,10012378,530,19362,180,9682,5.91942778579758e-06,1.472356253,1.238674592,1.756609434,6.84824645025041e-05,DB0040410012378_,9.588932838,0.386864011,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,4165,DB00451,10012378,814,46457,161,15258,8.74704002177571e-10,1.660440588,1.399126857,1.980784651,2.46030975893392e-08,DB0045110012378_,17.52039348,0.507082982,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,4167,DB00706,10012378,19,1056,151,15774,0.015953246,1.879544409,1.096430667,3.053222308,0.051718187,DB0070610012378_,2.961945785,0.631029412,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,tamsulosin,DB00706
,4169,DB00904,10012378,386,22683,117,14339,2.81643991587663e-13,2.085502542,1.68968364,2.590070335,1.36586943152799e-11,DB0090410012378_,25.01664485,0.735009854,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,4170,DB01076,10012378,343,25404,231,25352,3.69251750361873e-06,1.481790091,1.24927884,1.760156423,4.53012007386783e-05,DB0107610012378_,10.00217702,0.393250878,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,4171,DB01104,10012378,443,15020,209,7077,1,0.998693139,0.843220981,1.185909476,1,DB0110410012378_,0,-0.001307716,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,4186,DB00264,10018836,90,29517,72,24820,0.812794424,1.051099689,0.76204107,1.454233938,0.899360195,DB0026410018836_,0.106071663,0.049836939,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,4187,DB00316,10018836,139,65335,105,36848,0.027430905,0.746632962,0.575084033,0.971670448,0.07895547,DB0031610018836_,2.538871258,-0.292181563,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,4188,DB00404,10018836,38,19854,24,9838,0.347477834,0.784598877,0.458307729,1.368158679,0.516978256,DB0040410018836_,0.659754463,-0.242582677,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,4189,DB00451,10018836,105,47166,40,15379,0.386598952,0.855938703,0.589117415,1.265450276,0.556716894,DB0045110018836_,0.585698438,-0.155556515,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,4193,DB00904,10018836,68,23001,50,14406,0.395065834,0.851804683,0.582211219,1.253674662,0.564932429,DB0090410018836_,0.57104915,-0.160398024,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,4194,DB01076,10018836,83,25664,86,25497,0.817392094,0.958824725,0.700183541,1.312434831,0.902386086,DB0107610018836_,0.102712817,-0.042046989,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,4215,DB01255,10013968,41,2092,15,1563,0.019844012,2.041779936,1.101799755,3.986173173,0.061371908,DB0125510013968_,2.790803071,0.713821945,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisdexamfetamine,DB01255
,4223,DB08908,10028245,470,10203,201,3078,8.56558275054023e-05,0.705430835,0.593711589,0.840520845,0.000699104,DB0890810028245_,7.26571149,-0.348946549,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,4224,DB14726,10013968,99,1918,80,2768,0.000190056,1.785655548,1.308505936,2.443088375,0.001380196,DB1472610013968_,6.585529627,0.579785602,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dabigatran,DB14726
,4225,DB14726,10028813,63,1954,58,2790,0.019237631,1.550749848,1.062850949,2.266108559,0.059965744,DB1472610028813_,2.813981817,0.438738587,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dabigatran,DB14726
,4227,DB14726,10047700,46,1971,45,2803,0.085501129,1.453580353,0.938459366,2.252831313,0.187540966,DB1472610047700_,1.673757971,0.374029722,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dabigatran,DB14726
,4231,DB00374,10033318,636,17080,237,5487,0.059119519,0.862124139,0.739071517,1.008201305,0.14184808,DB0037410033318_,1.952998653,-0.148356006,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,treprostinil,DB00374
,4232,DB00374,10003997,69,17647,20,5704,0.804670857,1.115129661,0.669078166,1.938975077,0.894419007,DB0037410003997_,0.111580926,0.108970686,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,treprostinil,DB00374
,4233,DB00374,10021097,896,16820,295,5429,0.781844412,0.980347203,0.855379762,1.126054713,0.881222599,DB0037410021097_,0.126445019,-0.019848481,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,treprostinil,DB00374
,4234,DB00374,10046306,158,17558,33,5691,0.02208082,1.551804687,1.05959102,2.335177389,0.066819522,DB0037410046306_,2.705760001,0.439418568,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,4236,DB08908,10027599,73,10600,8,3271,0.002333786,2.815778926,1.354181464,6.77382792,0.011033018,DB0890810027599_,4.506862909,1.035238929,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,4241,DB00682,10042772,419,19040,215,16149,1.38154657189467e-09,1.652901633,1.396951031,1.960218916,3.73216358090971e-08,DB0068210042772_,17.10369263,0.502532309,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,4248,DB00005,10038435,115,127967,64,42355,0.001286889,0.594738804,0.434309229,0.820698846,0.006771269,DB0000510038435_,4.99506678,-0.519632956,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,etanercept,DB00005
,4249,DB01373,10012735,1303,21417,376,7005,0.038185917,1.133452361,1.006513121,1.278731474,0.101977833,DB0137310012735_,2.282999814,0.125268162,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,4252,DB08899,10016256,11,238,1122,7011,2.90210926971587e-06,0.288830786,0.141782346,0.528511755,3.68333858785523e-05,DB0889910016256_,10.2091059,-1.241914278,male,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,enzalutamide,DB08899
,4256,DB00207,10015150,52,9028,12,5443,0.001687095,2.612413061,1.374666275,5.381605191,0.008458804,DB0020710015150_,4.772547478,0.960274339,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,azithromycin,DB00207
,4257,DB09153,10015150,73,7726,34,5665,0.030406009,1.574253411,1.032730335,2.443466042,0.085556062,DB0915310015150_,2.458583427,0.453781135,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,sodium chloride,DB09153
,4258,DB00207,10020751,81,8999,41,5414,0.398916477,1.188598638,0.805343989,1.778176705,0.568783271,DB0020710020751_,0.564255812,0.172774998,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,azithromycin,DB00207
,4262,DB09153,10022086,60,7739,14,5685,2.72184833371762e-05,3.147967597,1.736476263,6.105535104,0.000260254,DB0915310022086_,8.253853056,1.146757037,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,4263,DB00451,10061623,267,47004,106,15313,0.091202706,0.820584153,0.652381635,1.038431458,0.197167671,DB0045110061623_,1.623700792,-0.197738811,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,4264,DB00451,10061822,320,46951,77,15342,0.016386774,1.357964913,1.055082381,1.766304589,0.052788326,DB0045110061822_,2.941465205,0.305987192,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,4265,DB00451,10069326,164,47107,25,15394,0.000176085,2.143572819,1.401184987,3.410539333,0.001295382,DB0045110069326_,6.648949746,0.762473979,NA,10069326,Product substitution issue,10077536,Product issues,Prod,levothyroxine,DB00451
,4267,DB08816,10017955,57,1094,75,1827,0.198795174,1.269091932,0.875734249,1.831019843,0.34759071,DB0881610017955_,1.056729613,0.238301631,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ticagrelor,DB08816
,4271,DB00327,10008531,66,6072,38,4224,0.369099872,1.20820297,0.79697151,1.855075791,0.538718981,DB0032710008531_,0.618561214,0.189134107,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,4272,DB00338,10008531,306,33368,175,22097,0.134349317,1.15789876,0.957744811,1.403538926,0.261777004,DB0033810008531_,1.340262267,0.146606949,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,4273,DB00404,10008531,196,19696,51,9811,1.69930381809721e-05,1.914311536,1.398853628,2.661763806,0.000172991,DB0040410008531_,8.662272675,0.649358047,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,4274,DB00471,10008531,141,14048,43,5422,0.186705968,1.2655653,0.892330878,1.82748227,0.332367097,DB0047110008531_,1.101515206,0.2355189,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,4275,DB00497,10008531,135,19132,132,16243,0.267299695,0.868296568,0.677347627,1.113291359,0.429591715,DB0049710008531_,0.844920022,-0.141221954,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,4276,DB00512,10008531,58,4679,52,5046,0.339291941,1.202845441,0.811038709,1.787892049,0.508363324,DB0051210008531_,0.676558882,0.184689951,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,4277,DB00588,10008531,176,16348,66,8402,0.028990938,1.370510333,1.025871991,1.8496909,0.08246151,DB0058810008531_,2.495423637,0.315183176,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,4278,DB00874,10008531,41,3294,19,1957,0.421648944,1.281973026,0.724999009,2.345626815,0.590716716,DB0087410008531_,0.526418706,0.248400318,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,4279,DB01069,10008531,79,6621,21,2374,0.254109934,1.348786536,0.822883923,2.303944972,0.414694664,DB0106910008531_,0.880212778,0.299205326,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,4280,DB01075,10008531,323,19625,257,10840,2.11008715717346e-05,0.694244889,0.586430492,0.822455688,0.00020906,DB0107510008531_,8.472888853,-0.364930515,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,4281,DB11089,10008531,101,10074,73,8334,0.400577991,1.144572473,0.837392598,1.57094721,0.570440595,DB1108910008531_,0.561346244,0.135031182,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,4283,DB00327,10037660,162,5976,111,4151,0.950308588,1.013756981,0.788628695,1.306968164,0.988576679,DB0032710037660_,0.011489068,0.013663213,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,4284,DB00338,10037660,720,32954,528,21744,0.069841719,0.899769915,0.801968958,1.009950079,0.160994335,DB0033810037660_,1.826386102,-0.105616199,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,4285,DB00404,10037660,351,19541,149,9713,0.113923802,1.170899227,0.962415504,1.430212712,0.232058829,DB0040410037660_,1.460764368,0.157772023,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,4286,DB00471,10037660,323,13866,121,5344,0.830389642,1.028820983,0.830219593,1.281662838,0.911043983,DB0047110037660_,0.093164103,0.02841347,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,4287,DB00588,10037660,412,16112,219,8249,0.670184324,0.963197704,0.813751369,1.142474847,0.799881713,DB0058810037660_,0.223291421,-0.037496588,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,4288,DB00874,10037660,90,3245,49,1927,0.657538406,1.090715701,0.758060747,1.585375815,0.790692277,DB0087410037660_,0.234846417,0.086834087,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,4289,DB01069,10037660,192,6508,70,2325,0.886895972,0.979894448,0.738316884,1.313014723,0.95298528,DB0106910037660_,0.048155821,-0.020310419,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,4290,DB11089,10037660,304,9871,258,8149,0.763321664,0.972733231,0.819129707,1.155868673,0.86898133,DB1108910037660_,0.140433638,-0.027645406,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,4336,DB00091,10015967,44,5466,10,2660,0.028287607,2.141066222,1.059544249,4.779353703,0.080898677,DB0009110015967_,2.514557804,0.76130394,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,cyclosporine,DB00091
,4338,DB00169,10015967,112,38579,21,18154,3.42352812460978e-05,2.509653679,1.564324802,4.214115561,0.00031854,DB0016910015967_,8.051763761,0.920144767,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,4339,DB00641,10015967,44,14080,15,12460,0.000949867,2.595627464,1.416172293,5.023749822,0.005279604,DB0064110015967_,5.243904112,0.953828285,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,simvastatin,DB00641
,4340,DB00678,10015967,39,15560,13,10711,0.023169727,2.065040555,1.078434334,4.218331094,0.069296954,DB0067810015967_,2.669354334,0.725149866,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,losartan,DB00678
,4341,DB01373,10015967,63,22657,9,7372,0.01878562,2.27741952,1.125944108,5.212303936,0.058818345,DB0137310015967_,2.833301476,0.823043013,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,calcium,DB01373
,4344,DB00091,10019211,261,5249,62,2608,5.64941478275684e-08,2.091440375,1.573219806,2.816686096,1.07878581594452e-06,DB0009110019211_,13.73967439,0.737853003,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cyclosporine,DB00091
,4345,DB00115,10019211,955,17470,257,10215,7.31445512466395e-31,2.172721384,1.886996858,2.508741072,1.73207615271885e-28,DB0011510019211_,63.92306183,0.775980476,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,4346,DB00126,10019211,564,9607,151,5794,1.62780405584087e-20,2.252535841,1.873059747,2.722005974,1.77538712065466e-18,DB0012610019211_,40.87251318,0.812056622,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,4347,DB00169,10019211,2069,36622,465,17710,6.40763710034984e-56,2.151684561,1.941607968,2.388249749,4.81213546236273e-53,DB0016910019211_,120.465869,0.766251052,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,4348,DB00641,10019211,646,13478,241,12234,2.86728082895773e-34,2.432860649,2.090840701,2.838785509,8.37405295435044e-32,DB0064110019211_,71.55758498,0.889067787,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,4349,DB00678,10019211,738,14861,273,10451,1.95230215880793e-20,1.901038393,1.648501617,2.197405598,2.1031255018142e-18,DB0067810019211_,40.7031071,0.64240026,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,losartan,DB00678
,4350,DB01373,10019211,953,21767,153,7228,5.92157245867411e-19,2.068351634,1.738177303,2.474697964,5.55887614558033e-17,DB0137310019211_,37.42855063,0.726751978,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,calcium,DB01373
,4352,DB13961,10019211,523,8934,180,6234,4.64048643131033e-17,2.027349756,1.702689521,2.422606359,3.57698492219918e-15,DB1396110019211_,33.26425615,0.706729401,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,4354,DB00115,10033433,76,18349,22,10450,0.004273202,1.967366369,1.209787573,3.323756502,0.018023284,DB0011510033433_,4.016090819,0.67669578,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,4355,DB00126,10033433,46,10125,12,5933,0.009455863,2.246136407,1.169736384,4.66258839,0.034035548,DB0012610033433_,3.380349778,0.809211588,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,4356,DB00169,10033433,160,38531,31,18144,1.1079161679392e-06,2.430386171,1.645616884,3.697000965,1.56609714838837e-05,DB0016910033433_,11.06433883,0.888050163,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,4357,DB00451,10033433,185,47086,25,15394,5.78353542399926e-06,2.419405252,1.587553227,3.837089529,6.71238974665629e-05,DB0045110033433_,9.60897043,0.883521746,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,4358,DB00641,10033433,60,14064,15,12460,2.03116062621709e-06,3.543500429,1.986148133,6.723444745,2.68556625050887e-05,DB0064110033433_,10.52503387,1.26511506,female,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,4359,DB00678,10033433,48,15551,21,10703,0.086558936,1.573118613,0.92340813,2.767662054,0.18930041,DB0067810033433_,1.664420055,0.453060027,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,4360,DB01373,10033433,141,22579,20,7361,0.000209868,2.298166789,1.431873405,3.880333449,0.001500237,DB0137310033433_,6.502132086,0.832111757,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,4366,DB00169,10047531,51,38640,19,18156,0.44265305,1.26120716,0.731678443,2.2628154,0.610688121,DB0016910047531_,0.49316889,0.232069326,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,4395,DB00451,10027951,77,47194,24,15395,0.908338033,1.046609868,0.65422832,1.731681777,0.958996855,DB0045110027951_,0.041867483,0.045556244,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,4396,DB00422,10001488,37,3398,103,2846,4.36652087530655e-11,0.300921694,0.200148307,0.443672493,1.5161691044575e-09,DB0042210001488_,20.30707901,-1.200905202,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,methylphenidate,DB00422
,4397,DB00472,10001488,27,10732,48,4264,2.01568803597259e-10,0.223518026,0.133912733,0.366026619,6.27010177817036e-09,DB0047210001488_,18.88747325,-1.498263214,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,4400,DB00184,10035664,35,1259,24,958,0.79030839,1.109663357,0.636706225,1.9639652,0.886410114,DB0018410035664_,0.120575553,0.104056688,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,nicotine,DB00184
,4401,DB00231,10035664,123,3173,107,2032,0.027125671,0.736222471,0.560004941,0.969081485,0.078291233,DB0023110035664_,2.547319651,-0.306222936,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,temazepam,DB00231
,4402,DB00316,10035664,2063,63411,1452,35501,7.46686580627897e-11,0.795458418,0.742485514,0.852323414,2.49227387578467e-09,DB0031610035664_,19.81007034,-0.228836704,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,4403,DB00338,10035664,1295,32379,1059,21213,1.89455445559872e-07,0.80115919,0.736709693,0.871346094,3.23576113485461e-06,DB0033810035664_,12.64124638,-0.221695613,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,omeprazole,DB00338
,4404,DB00904,10035664,1008,22061,794,13662,8.85206036309678e-07,0.786209756,0.713909823,0.86604424,1.28763921773104e-05,DB0090410035664_,11.26011499,-0.240531657,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ondansetron,DB00904
,4406,DB08934,10035664,44,4445,48,6156,0.288727505,1.269476626,0.82218607,1.956025709,0.45377754,DB0893410035664_,0.790148201,0.23860471,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sofosbuvir,DB08934
,4407,DB11089,10035664,512,9663,475,7932,0.065696133,0.884810997,0.776613324,1.008191053,0.153637195,DB1108910035664_,1.873161335,-0.12238122,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,docusate,DB11089
,4410,DB00338,10038687,65,33609,51,22221,0.392985366,0.8426651,0.574790822,1.241221339,0.562968108,DB0033810038687_,0.574532298,-0.171185672,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,4411,DB00904,10038687,58,23011,57,14399,0.01637069,0.636752509,0.43380104,0.934926708,0.052746211,DB0090410038687_,2.942263334,-0.451374224,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,4414,DB11089,10038687,33,10142,28,8379,1,0.973691865,0.570023413,1.674002722,1,DB1108910038687_,0,-0.026660386,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,4417,DB00316,10048709,53,65421,43,36910,0.088391416,0.695429393,0.45621176,1.065364658,0.192546999,DB0031610048709_,1.647415007,-0.363225793,NA,10048709,Urosepsis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,4419,DB00904,10048709,31,23038,22,14434,0.67325662,0.882843585,0.494735933,1.600912296,0.801782854,DB0090410048709_,0.220917464,-0.124607234,NA,10048709,Urosepsis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,4424,DB00231,10053762,76,3220,44,2095,0.571840745,1.123804742,0.761878713,1.675292836,0.721961933,DB0023110053762_,0.325782865,0.116720019,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,temazepam,DB00231
,4425,DB00316,10053762,1763,63711,940,36013,0.155428234,1.060159661,0.9778518,1.149892367,0.291400222,DB0031610053762_,1.233057622,0.058419521,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,4426,DB00338,10053762,873,32801,504,21768,0.014157407,1.149474523,1.027537859,1.287068026,0.047021411,DB0033810053762_,3.057152219,0.139304902,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,4427,DB00904,10053762,629,22440,393,14063,0.974015491,1.003028316,0.881246529,1.142705037,1,DB0090410053762_,0,0.00302374,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,4428,DB11089,10053762,233,9942,185,8222,0.69125548,1.041574189,0.853074186,1.273106619,0.813815434,DB1108910053762_,0.206021679,0.040733212,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,4429,DB06228,10030124,204,15708,118,15958,9.55060547801047e-07,1.756286016,1.391698562,2.224778652,1.37517208978091e-05,DB0622810030124_,11.19434659,0.563201361,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,4431,DB08896,10003549,79,744,105,935,0.754743832,0.945546611,0.685774829,1.299706154,0.862297247,DB0889610003549_,0.148155234,-0.055992095,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,regorafenib,DB08896
,4433,DB08896,10029331,52,771,80,960,0.27559361,0.809430091,0.552186136,1.178144454,0.43887203,DB0889610029331_,0.823547412,-0.21142487,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,regorafenib,DB08896
,4437,DB00451,10035664,1544,45727,656,14763,1.37121312074285e-08,0.759884282,0.691777367,0.83541179,2.9885851474897e-07,DB0045110035664_,15.02329557,-0.274589117,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,4438,DB01080,10035664,86,1973,113,1999,0.081225674,0.771141362,0.571549284,1.037450866,0.180455899,DB0108010035664_,1.712268855,-0.259883573,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,vigabatrin,DB01080
,4440,DB01080,10038687,28,2031,30,2082,0.8954478,0.956767643,0.548665321,1.663813304,0.95615204,DB0108010038687_,0.044838341,-0.044194714,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vigabatrin,DB01080
,4441,DB01046,10013968,38,847,12,316,0.745480216,1.181259908,0.594964198,2.515845784,0.854760084,DB0104610013968_,0.156934453,0.166581588,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lubiprostone,DB01046
,4442,DB00448,10053762,156,4989,92,3032,0.84217176,1.030508746,0.788065573,1.353822796,0.919652051,DB0044810053762_,0.083759886,0.030052608,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lansoprazole,DB00448
,4443,DB01033,10053762,60,1122,65,1239,0.92703526,1.019329526,0.698608993,1.485237048,0.969199204,DB0103310053762_,0.031285111,0.019145084,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,mercaptopurine,DB01033
,4444,DB00448,10067482,34,5111,41,3083,0.003773185,0.50025492,0.307227609,0.809891937,0.016272052,DB0044810067482_,4.118306229,-0.692637471,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,4446,DB00310,10021036,25,919,33,748,0.081005851,0.616795478,0.34828243,1.079918272,0.180054863,DB0031010021036_,1.714493679,-0.483217788,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,chlorthalidone,DB00310
,4447,DB00363,10029354,754,3874,1208,5680,0.085615637,0.915130357,0.827078868,1.012206013,0.187743368,DB0036310029354_,1.672679311,-0.088688757,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,clozapine,DB00363
,4448,DB00181,10043414,121,9735,152,5719,6.0776084705991e-10,0.467671723,0.364392433,0.599165829,1.75549383131536e-08,DB0018110043414_,17.85793054,-0.759988675,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,4449,DB00181,10059650,96,9760,141,5730,3.75429852850004e-12,0.399743231,0.304482671,0.522939759,1.53590251862449e-10,DB0018110059650_,22.59673276,-0.916932861,NA,10059650,Implant site infection,10021881,Infections and infestations,Infec,baclofen,DB00181
,4451,DB00005,10067255,212,127870,35,42384,4.66102272659643e-05,2.007584199,1.398952659,2.959659752,0.000416081,DB0000510067255_,7.784631161,0.696932108,NA,10067255,Injection site macule,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,4453,DB00285,10038435,42,10909,15,3703,0.878935773,0.950444114,0.515646947,1.847376483,0.9491127,DB0028510038435_,0.05222773,-0.050825915,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,venlafaxine,DB00285
,4458,DB01234,10062355,510,31115,661,32227,0.000158155,0.799136812,0.709788677,0.899297463,0.00118049,DB0123410062355_,6.741825339,-0.224223119,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,4459,DB08910,10062355,245,16499,291,17197,0.138813533,0.877546344,0.736350252,1.045185167,0.268120198,DB0891010062355_,1.316319898,-0.130625511,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,4460,DB00682,10015090,377,19082,301,16063,0.508374831,1.054344419,0.90232209,1.232755166,0.668934342,DB0068210015090_,0.402069367,0.05291917,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,4461,DB00682,10022595,690,18769,1204,15160,6.2282588383114e-58,0.462899131,0.419878955,0.509991283,4.96090253227319e-55,DB0068210022595_,125.0405924,-0.770246108,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,warfarin,DB00682
,4462,DB00316,10003549,1770,63704,1089,35864,0.024336155,0.91503682,0.847085591,0.988810402,0.072036467,DB0031610003549_,2.630582798,-0.088790974,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,4463,DB01075,10003549,449,19499,279,10818,0.1476544,0.892852939,0.765772154,1.04246823,0.280740418,DB0107510003549_,1.270324815,-0.113333393,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,4465,DB01075,10006002,89,19859,36,11061,0.112184528,1.376956524,0.924462038,2.089974925,0.229333513,DB0107510006002_,1.472577947,0.319875646,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,4468,DB00316,10036018,164,65310,78,36875,0.22791082,1.187109687,0.90094506,1.57564089,0.383302572,DB0031610036018_,0.958930597,0.171521518,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,4469,DB01075,10036018,44,19904,18,11079,0.291430416,1.36061807,0.769829827,2.502977883,0.456906348,DB0107510036018_,0.783276836,0.307939059,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,diphenhydramine,DB01075
,4471,DB00316,10044390,165,65309,91,36862,0.896411195,1.023407631,0.78731974,1.337309565,0.956301489,DB0031610044390_,0.044682051,0.023137874,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,4472,DB01075,10044390,42,19906,21,11076,0.792694227,1.112840172,0.643995695,1.979130311,0.887600067,DB0107510044390_,0.119234013,0.106915461,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,4480,DB14512,10013968,356,4488,158,2254,0.224701408,1.131602627,0.92900884,1.383073494,0.379410067,DB1451210013968_,0.969137688,0.123634882,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mometasone furoate,DB14512
,4483,DB14726,10037377,29,1988,44,2804,0.811514647,0.929623996,0.558815648,1.525408176,0.898700758,DB1472610037377_,0.106805161,-0.07297508,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dabigatran,DB14726
,4484,DB14726,10051055,26,1991,47,2801,0.339476977,0.778286367,0.461010595,1.287720825,0.508572133,DB1472610051055_,0.67614822,-0.250660742,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,dabigatran,DB14726
,4485,DB00203,10019211,2009,11869,676,8262,3.15461075508669e-59,2.068632047,1.886450565,2.270490741,2.5513521137678e-56,DB0020310019211_,128.0081417,0.726887542,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,4487,DB00956,10042674,45,5769,16,3451,0.083831673,1.682341441,0.931085588,3.193857441,0.184804421,DB0095610042674_,1.688457196,0.520186538,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,4488,DB00264,10007559,421,29186,402,24490,0.066800627,0.878763151,0.763857024,1.011081771,0.155571212,DB0026410007559_,1.860651698,-0.12923987,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,metoprolol,DB00264
,4489,DB00331,10007559,261,24685,289,20463,0.000769217,0.748660351,0.630189228,0.889080596,0.004425714,DB0033110007559_,5.420323668,-0.289469869,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,metformin,DB00331
,4490,DB01592,10007559,75,6201,43,3024,0.430048997,0.850601244,0.575463107,1.271292127,0.598524293,DB0159210007559_,0.513288165,-0.161811834,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,iron,DB01592
,4491,DB00264,10007636,32,29575,49,24843,0.009815947,0.54858445,0.33989724,0.874249068,0.035048856,DB0026410007636_,3.351012291,-0.600414045,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,metoprolol,DB00264
,4492,DB00331,10007636,24,24922,46,20706,0.000700734,0.433483055,0.252979569,0.725317848,0.004095794,DB0033110007636_,5.497794773,-0.835902572,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,metformin,DB00331
,4493,DB00412,10007636,52,1012,66,1320,0.92426189,1.027667273,0.693705394,1.515683659,0.967261512,DB0041210007636_,0.033286383,0.02729145,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,4499,DB00264,10028596,325,29282,485,24407,3.5454434934512e-16,0.558554943,0.48332967,0.644839726,2.49176423062473e-14,DB0026410028596_,31.32320032,-0.582402289,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,metoprolol,DB00264
,4500,DB00331,10028596,264,24682,399,20353,1.68288643447908e-14,0.545620935,0.464738047,0.639754534,9.61623259353971e-13,DB0033110028596_,27.67015364,-0.605830803,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,metformin,DB00331
,4501,DB01592,10028596,32,6244,30,3037,0.013793001,0.518832422,0.30471573,0.885700588,0.046005842,DB0159210028596_,3.078986886,-0.656174335,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,iron,DB01592
,4502,DB00264,10061024,235,29372,270,24622,0.000455596,0.729625415,0.609427058,0.873035448,0.002857052,DB0026410061024_,5.857964799,-0.315224007,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,metoprolol,DB00264
,4503,DB00331,10061024,115,24831,146,20606,0.000732908,0.653662805,0.507059727,0.840979676,0.004248892,DB0033110061024_,5.461096927,-0.425163649,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,metformin,DB00331
,4504,DB00412,10061024,68,996,94,1292,0.74310098,0.938401001,0.668930184,1.310951695,0.852980884,DB0041210061024_,0.159018143,-0.063577915,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,4505,DB01592,10061024,42,6234,26,3041,0.364709635,0.788043054,0.47100575,1.341497579,0.534352466,DB0159210061024_,0.626699609,-0.238202553,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,iron,DB01592
,4507,DB00412,10003210,24,1040,38,1348,0.516971921,0.818689839,0.466636318,1.410717733,0.676622364,DB0041210003210_,0.390641969,-0.200049974,NA,10003210,Arteriosclerosis,10047065,Vascular disorders,Vasc,rosiglitazone,DB00412
,4509,DB00412,10003211,34,1030,96,1290,3.69226919643703e-05,0.443716067,0.288323391,0.668765308,0.000340411,DB0041210003211_,7.985355613,-0.812570409,NA,10003211,Arteriosclerosis coronary artery,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,4510,DB00412,10008190,135,929,186,1200,0.629059112,0.937538304,0.733233712,1.196596164,0.768168119,DB0041210008190_,0.263746664,-0.064497664,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,rosiglitazone,DB00412
,4511,DB00412,10011906,29,1035,35,1351,0.798862929,1.081510605,0.633159385,1.834753722,0.891356522,DB0041210011906_,0.115010795,0.078358772,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,rosiglitazone,DB00412
,4512,DB00264,10044390,105,29502,92,24800,0.774944136,0.959387392,0.717851168,1.284088859,0.877323349,DB0026410044390_,0.130879655,-0.041460332,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,4513,DB00412,10044390,50,1014,69,1317,0.776772919,0.941181463,0.634455228,1.387982916,0.878377873,DB0041210044390_,0.129678399,-0.060619317,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,rosiglitazone,DB00412
,4515,DB00695,10013710,196,27853,182,20346,0.021400678,0.786678983,0.639076392,0.968706131,0.065226903,DB0069510013710_,2.72988327,-0.239935013,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,4518,DB00005,10066901,1680,126402,477,41942,0.00262783,1.168649965,1.054375953,1.297224488,0.012136405,DB0000510066901_,4.411545645,0.155849206,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,4519,DB00073,10003549,233,7173,206,6201,0.845794928,0.977795257,0.804596036,1.189003205,0.922477996,DB0007310003549_,0.080691756,-0.022454979,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,4520,DB00073,10005483,46,7360,46,6361,0.529564222,0.864276762,0.560839052,1.331869543,0.686844744,DB0007310005483_,0.375647004,-0.145862235,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,rituximab,DB00073
,4521,DB00073,10016256,401,7005,330,6077,0.493067234,1.054183726,0.905205685,1.228266515,0.655851033,DB0007310016256_,0.4218216,0.052766748,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,4522,DB00073,10018364,39,7367,29,6378,0.545402864,1.164274779,0.700780421,1.954536145,0.700149656,DB0007310018364_,0.356461172,0.152098386,NA,10018364,Glomerulonephritis,10038359,Renal and urinary disorders,Renal,rituximab,DB00073
,4523,DB00073,10018867,43,7363,38,6369,1,0.978813325,0.616996912,1.558248613,1,DB0007310018867_,0,-0.021414334,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,rituximab,DB00073
,4524,DB00073,10018884,69,7337,79,6328,0.097245999,0.753323563,0.536388132,1.055872761,0.206704762,DB0007310018884_,1.576463777,-0.283260444,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,rituximab,DB00073
,4525,DB00073,10037032,35,7371,26,6381,0.607843624,1.165338339,0.680864166,2.01831713,0.750716773,DB0007310037032_,0.286726832,0.153011465,NA,10037032,Proteinuria,10038359,Renal and urinary disorders,Renal,rituximab,DB00073
,4526,DB00073,10037844,309,7097,195,6212,0.00044928,1.386976937,1.151693377,1.673448841,0.002824521,DB0007310037844_,5.869416646,0.327126513,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,rituximab,DB00073
,4528,DB00005,10056871,230,127852,47,42372,0.002132405,1.621755436,1.180492173,2.27010274,0.010258099,DB0000510056871_,4.57968773,0.483509165,NA,10056871,Device failure,10077536,Product issues,Prod,etanercept,DB00005
,4529,DB00005,10023230,765,127317,328,42091,0.000111369,0.771065384,0.676288113,0.88067646,0.000875009,DB0000510023230_,7.041276111,-0.259982105,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,4530,DB00688,10003549,103,6387,69,5309,0.189560819,1.240782752,0.903775005,1.712314479,0.33599286,DB0068810003549_,1.090665369,0.215742432,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,4531,DB00688,10005483,65,6425,111,5267,2.60797285591565e-06,0.480068586,0.347100873,0.659369046,3.34393007403623e-05,DB0068810005483_,10.30577868,-0.733826297,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,mycophenolate mofetil,DB00688
,4532,DB00688,10013968,254,6236,134,5244,1.26202527048905e-05,1.593924012,1.283559966,1.986400382,0.000133195,DB0068810013968_,8.923692736,0.466198908,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolate mofetil,DB00688
,4533,DB00688,10016256,222,6268,144,5234,0.021722875,1.287317,1.035596219,1.604249853,0.065999758,DB0068810016256_,2.71810421,0.252560208,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,4535,DB00688,10018867,31,6459,45,5333,0.015302505,0.56882964,0.34745136,0.920338209,0.050102933,DB0068810018867_,2.993675739,-0.564174292,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,mycophenolate mofetil,DB00688
,4536,DB00688,10037032,42,6448,32,5346,0.814976553,1.088208628,0.669694084,1.783656405,0.90068368,DB0068810037032_,0.104601159,0.084532883,NA,10037032,Proteinuria,10038359,Renal and urinary disorders,Renal,mycophenolate mofetil,DB00688
,4537,DB00688,10061428,77,6413,60,5318,0.730858744,1.064219755,0.747931665,1.520390377,0.843454003,DB0068810061428_,0.170249909,0.062241906,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,mycophenolate mofetil,DB00688
,4538,DB00203,10056520,116,13762,40,8898,0.000505689,1.874980729,1.29720094,2.760475924,0.003116538,DB0020310056520_,5.771032449,0.628598382,NA,10056520,Catheter site infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,4539,DB00374,10056520,106,17610,32,5692,0.842440525,1.070680039,0.714166874,1.645535146,0.919801687,DB0037410056520_,0.08359719,0.068293997,NA,10056520,Catheter site infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,4540,DB00559,10056520,58,9601,25,3281,0.376000745,0.792833783,0.487242317,1.325072254,0.545760648,DB0055910056520_,0.605574773,-0.232141684,NA,10056520,Catheter site infection,10021881,Infections and infestations,Infec,bosentan,DB00559
,4541,DB00682,10056520,119,19340,26,16338,3.34447194506317e-12,3.866257999,2.511309533,6.162783921,1.37897168746644e-10,DB0068210056520_,22.70451286,1.352287114,female,10056520,Catheter site infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,4548,DB00215,10028334,139,10964,39,5237,0.00276405,1.702358352,1.18383262,2.498872121,0.012641912,DB0021510028334_,4.370737653,0.532014556,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,4549,DB00338,10028334,580,33094,299,21973,0.000391927,1.28793753,1.117060195,1.487375171,0.002520629,DB0033810028334_,5.98324694,0.253042125,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,4551,DB00927,10028334,89,7408,57,4959,0.86518478,1.045222591,0.739670323,1.487258956,0.938504919,DB0092710028334_,0.063467181,0.044229869,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,famotidine,DB00927
,4552,DB00950,10028334,79,4639,28,2028,0.396689789,1.233366298,0.789540658,1.978440017,0.56626883,DB0095010028334_,0.568686349,0.209747258,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,fexofenadine,DB00950
,4553,DB00215,10042674,65,11038,14,5262,0.005207803,2.213236753,1.2278963,4.274769057,0.021139231,DB0021510042674_,3.856624676,0.794456038,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,4554,DB00338,10042674,289,33385,85,22187,3.26733432289057e-12,2.259530159,1.767241484,2.914684948,1.3482242178521e-10,DB0033810042674_,22.7270626,0.815156897,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,4556,DB00927,10042674,74,7423,40,4976,0.292067837,1.240113581,0.831609085,1.873567806,0.457536391,DB0092710042674_,0.781898855,0.215202973,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,4557,DB00950,10042674,44,4674,6,2050,0.003152272,3.215756917,1.362454853,9.248473109,0.0140875,DB0095010042674_,4.262467371,1.168062763,female,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,4563,DB00374,10007515,144,17572,63,5661,0.050735805,0.73637682,0.54313972,1.00811362,0.126376749,DB0037410007515_,2.068487761,-0.306013307,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,treprostinil,DB00374
,4564,DB00559,10007515,98,9561,40,3266,0.376584166,0.836892573,0.572482779,1.243940262,0.546421352,DB0055910007515_,0.604364893,-0.178059564,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,bosentan,DB00559
,4565,DB00559,10013968,1598,8061,468,2838,0.001157291,1.202150119,1.074170295,1.347016492,0.006215651,DB0055910013968_,5.080684817,0.184111719,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,4566,DB00559,10038695,181,9478,82,3224,0.037947495,0.750850284,0.573421301,0.990113866,0.101506483,DB0055910038695_,2.287632606,-0.286549003,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,4567,DB00374,10069841,47,17669,14,5710,0.881993873,1.08490649,0.586682445,2.135425747,0.950618512,DB0037410069841_,0.050642441,0.081493799,NA,10069841,Device alarm issue,10077536,Product issues,Prod,treprostinil,DB00374
,4569,DB01362,10020751,51,815,19,571,0.02406127,1.8798258,1.077284383,3.409809091,0.071382672,DB0136210020751_,2.639700133,0.631179113,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,iohexol,DB01362
,4576,DB00169,10013990,95,38596,40,18135,0.644153046,1.115928796,0.763304208,1.658429183,0.780364236,DB0016910013990_,0.247994499,0.109687059,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,4577,DB00181,10013990,47,9809,23,5848,0.460630208,1.218239,0.724215454,2.104406714,0.627974638,DB0018110013990_,0.465255498,0.197406373,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,baclofen,DB00181
,4579,DB00169,10016750,42,38649,16,18159,0.573420124,1.233310866,0.678803983,2.350577649,0.723293325,DB0016910016750_,0.323940434,0.209702314,NA,10016750,Flank pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,4582,DB00169,10018867,50,38641,77,18098,4.16395624127472e-11,0.304138631,0.208573572,0.440019314,1.44774589685061e-09,DB0016910018867_,20.35325804,-1.190271659,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,4585,DB00169,10021789,393,38298,168,18007,0.317044649,1.099883555,0.914959414,1.326846586,0.484839534,DB0016910021789_,0.723937301,0.095204315,NA,10021789,Infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,4586,DB00181,10021789,125,9731,111,5760,0.002236333,0.666623207,0.51095318,0.870545381,0.010652773,DB0018110021789_,4.541935064,-0.4055303,NA,10021789,Infection,10021881,Infections and infestations,Infec,baclofen,DB00181
,4587,DB08868,10021789,54,9148,12,2499,0.651598153,1.229261512,0.648218454,2.528577394,0.785978498,DB0886810021789_,0.240825843,0.206413592,NA,10021789,Infection,10021881,Infections and infestations,Infec,fingolimod,DB08868
,4588,DB00181,10024264,97,9759,88,5783,0.004568615,0.653230782,0.48345775,0.883546668,0.018998166,DB0018110024264_,3.963412813,-0.425824794,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,4590,DB00169,10027566,59,38632,16,18159,0.048021313,1.733296826,0.984011855,3.228122682,0.121392597,DB0016910027566_,2.108725385,0.550025275,NA,10027566,Micturition urgency,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,4592,DB08868,10027566,70,9132,20,2491,0.897336206,0.954718909,0.57269137,1.660582513,0.956338178,DB0886810027566_,0.044643686,-0.046338318,NA,10027566,Micturition urgency,10038359,Renal and urinary disorders,Renal,fingolimod,DB08868
,4593,DB00169,10029148,159,38532,88,18087,0.218786131,0.848139069,0.649217358,1.114025175,0.372039039,DB0016910029148_,0.988756487,-0.164710661,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,4594,DB00181,10029148,45,9811,32,5839,0.478933891,0.836944295,0.519598167,1.362391667,0.644141393,DB0018110029148_,0.439837022,-0.177997764,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,baclofen,DB00181
,4596,DB00181,10037660,242,9614,189,5682,0.005425576,0.756777854,0.621247111,0.922953824,0.021831041,DB0018110037660_,3.824422438,-0.278685525,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,4597,DB00169,10068319,322,38369,66,18109,2.56977190101802e-11,2.302610162,1.761012203,3.050327538,9.18374635190466e-10,DB0016910068319_,20.80841571,0.834043332,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,4598,DB00181,10068319,42,9814,14,5857,0.070965301,1.790339047,0.957472161,3.55264988,0.162993522,DB0018110068319_,1.814044818,0.582405013,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,baclofen,DB00181
,4599,DB08868,10068319,217,8985,53,2458,0.499988999,1.120065168,0.823094378,1.547705087,0.661659451,DB0886810068319_,0.41300428,0.113386869,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fingolimod,DB08868
,4603,DB00108,10057668,146,10048,45,3250,0.865307643,1.049372466,0.744702683,1.50406937,0.938599459,DB0010810057668_,0.063366452,0.048192334,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,4604,DB00060,10022086,291,9217,58,2407,0.069387239,1.310207055,0.981613635,1.774627552,0.160218172,DB0006010022086_,1.831218816,0.270185182,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,4610,DB00316,10011224,1180,64294,578,36375,0.005010298,1.155037253,1.043832315,1.279129229,0.020495384,DB0031610011224_,3.887555606,0.144132597,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,4611,DB00924,10011224,179,9983,55,4196,0.043072403,1.367848725,1.003603198,1.890062831,0.111823608,DB0092410011224_,2.190832578,0.313239232,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,4612,DB01362,10011224,37,829,19,571,0.3337366,1.34104834,0.742940615,2.495273377,0.502838356,DB0136210011224_,0.687486521,0.293451652,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iohexol,DB01362
,4613,DB00316,10046735,682,64792,293,36660,7.54068224707699e-05,1.317002743,1.146106897,1.516401675,0.000625752,DB0031610046735_,7.376557002,0.275358506,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,4614,DB00924,10046735,103,10059,18,4233,0.000272399,2.407890319,1.448187643,4.22867289,0.001864502,DB0092410046735_,6.284761142,0.878750978,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,cyclobenzaprine,DB00924
,4615,DB01362,10046735,201,665,119,471,0.176243328,1.196175599,0.919940702,1.559670605,0.319024576,DB0136210046735_,1.142487139,0.179129467,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,iohexol,DB01362
,4616,DB00864,10053762,667,6202,830,7562,0.722195045,0.979833346,0.878702509,1.09231724,0.836361491,DB0086410053762_,0.178694354,-0.020372777,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tacrolimus,DB00864
,4618,DB00864,10061822,54,6815,25,8367,3.41233338170683e-05,2.651745693,1.620010815,4.451956455,0.000317779,DB0086410061822_,8.054153714,0.975218175,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,4619,DB01222,10016322,154,9120,45,5360,2.14438769836489e-05,2.011217231,1.431699566,2.87478823,0.000212019,DB0122210016322_,8.458835028,0.698740126,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,4620,DB00051,10021789,514,25217,208,11212,0.271497369,1.098720981,0.931947023,1.299106832,0.434293351,DB0005110021789_,0.83403505,0.094146759,NA,10021789,Infection,10021881,Infections and infestations,Infec,adalimumab,DB00051
,4621,DB00051,10035664,469,25262,231,11189,0.199845211,0.899265776,0.765301347,1.059015292,0.348811804,DB0005110035664_,1.053222745,-0.106176653,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,adalimumab,DB00051
,4623,DB06404,10048961,56,3013,22,878,0.273581764,0.741815809,0.442813578,1.283469955,0.436591383,DB0640410048961_,0.828757572,-0.298654303,NA,10048961,Localised oedema,10018065,General disorders and administration site conditions,Genrl,human c1-esterase inhibitor,DB06404
,4624,DB00997,10008479,46,5285,22,3492,0.262694735,1.381493644,0.812678194,2.41596577,0.424448679,DB0099710008479_,0.856964177,0.323165264,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,4625,DB00531,10013968,236,7016,164,6352,0.010985444,1.302806425,1.05973071,1.604737172,0.03837751,DB0053110013968_,3.260283671,0.264520726,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclophosphamide,DB00531
,4626,DB00997,10013968,207,5124,90,3424,0.000709381,1.536851419,1.189467722,1.998782583,0.004139896,DB0099710013968_,5.487084589,0.429735791,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxorubicin,DB00997
,4627,DB01229,10013968,414,5327,166,2543,0.07211221,1.190577784,0.985598524,1.443203519,0.164975847,DB0122910013968_,1.801956198,0.174438722,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,paclitaxel,DB01229
,4650,DB00181,10013754,396,9460,447,5424,2.39142260353489e-21,0.507955322,0.440715206,0.585291816,2.87682119606016e-19,DB0018110013754_,42.69243083,-0.677361785,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,4651,DB00295,10013754,118,14545,133,9469,1.68551456198949e-05,0.577624153,0.446299046,0.746803509,0.00017182,DB0029510013754_,8.66906397,-0.548831876,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,4653,DB00921,10013754,489,5356,592,4311,2.52139185406311e-10,0.664887474,0.584680175,0.755839488,7.73786163269689e-09,DB0092110013754_,18.67714046,-0.408137464,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,4654,DB00924,10013754,58,10104,18,4233,0.313304788,1.349856023,0.782941017,2.437604652,0.480860466,DB0092410013754_,0.732178142,0.299997937,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,4657,DB00295,10021789,83,14580,70,9532,0.13521953,0.775206107,0.556529127,1.082347928,0.262985226,DB0029510021789_,1.335657422,-0.25462634,NA,10021789,Infection,10021881,Infections and infestations,Infec,morphine,DB00295
,4658,DB00736,10021789,103,10488,47,5506,0.48974862,1.150467834,0.805865484,1.66370284,0.653089264,DB0073610021789_,0.426041461,0.140168671,NA,10021789,Infection,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,4660,DB00924,10021789,99,10063,22,4229,0.005006488,1.891063561,1.180381335,3.157695993,0.020486578,DB0092410021789_,3.887985362,0.637139402,NA,10021789,Infection,10021881,Infections and infestations,Infec,cyclobenzaprine,DB00924
,4661,DB00950,10021789,53,4665,15,2041,0.146313704,1.545792909,0.855975547,2.960043129,0.278800402,DB0095010021789_,1.277259159,0.435536988,NA,10021789,Infection,10021881,Infections and infestations,Infec,fexofenadine,DB00950
,4662,DB01098,10021789,64,8085,37,7172,0.044949988,1.534352968,1.006684761,2.369420438,0.115477488,DB0109810021789_,2.158679674,0.428108773,NA,10021789,Infection,10021881,Infections and infestations,Infec,rosuvastatin,DB01098
,4663,DB00181,10028335,400,9456,519,5352,1.02737023079184e-33,0.436235884,0.380281611,0.500170977,2.88817395896936e-31,DB0018110028335_,70.31951343,-0.829572165,NA,10028335,Muscle spasticity,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,4670,DB00295,10043414,37,14626,27,9575,0.701749486,0.897127087,0.53124151,1.533124754,0.820985212,DB0029510043414_,0.197250182,-0.108557747,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,4672,DB00921,10043414,41,5804,25,4878,0.217259986,1.37830314,0.817073148,2.368635871,0.370205693,DB0092110043414_,0.993696501,0.320853134,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,4676,DB00181,10046571,531,9325,235,5636,9.15547614672646e-05,1.365652851,1.164750982,1.604966306,0.000740125,DB0018110046571_,7.208691273,0.311632593,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,baclofen,DB00181
,4677,DB00295,10046571,193,14470,89,9513,0.005773924,1.42564039,1.10184074,1.856572054,0.022962039,DB0029510046571_,3.773912895,0.354621109,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,morphine,DB00295
,4678,DB00736,10046571,264,10327,31,5522,1.59486558271593e-21,4.553037206,3.126549523,6.848161433,1.9498158996134e-19,DB0073610046571_,43.08138181,1.515794528,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,4680,DB00924,10046571,202,9960,38,4213,9.87605880228614e-07,2.248431299,1.580260432,3.275824046,1.41505699437499e-05,DB0092410046571_,11.16575566,0.810232773,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,cyclobenzaprine,DB00924
,4681,DB00950,10046571,115,4603,9,2047,3.44108894902467e-10,5.681788136,2.883065005,12.764985,1.03666502034514e-08,DB0095010046571_,18.38467189,1.737265996,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,fexofenadine,DB00950
,4682,DB01098,10046571,172,7977,69,7140,7.10661074172217e-09,2.230996379,1.674688593,3.000198889,1.64942395890655e-07,DB0109810046571_,15.61766954,0.802448292,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,rosuvastatin,DB01098
,4683,DB00181,10047895,139,9717,68,5803,0.193136604,1.220694824,0.905208759,1.659641586,0.340562549,DB0018110047895_,1.077156473,0.199420224,NA,10047895,Weight decreased,10022891,Investigations,Inv,baclofen,DB00181
,4684,DB00736,10047895,228,10363,143,5410,0.097053184,0.832379983,0.67058082,1.036028915,0.206361668,DB0073610047895_,1.578124979,-0.183466233,NA,10047895,Weight decreased,10022891,Investigations,Inv,esomeprazole,DB00736
,4685,DB00921,10047895,67,5778,48,4855,0.451672101,1.172839701,0.795910293,1.739776047,0.619295333,DB0092110047895_,0.479173007,0.159427903,NA,10047895,Weight decreased,10022891,Investigations,Inv,buprenorphine,DB00921
,4686,DB00924,10047895,178,9984,70,4181,0.725482621,1.064867187,0.801218801,1.428439678,0.839115122,DB0092410047895_,0.175407369,0.062850084,NA,10047895,Weight decreased,10022891,Investigations,Inv,cyclobenzaprine,DB00924
,4687,DB00950,10047895,85,4633,48,2008,0.153333908,0.767509433,0.530356138,1.12193373,0.288647266,DB0095010047895_,1.242549871,-0.264604509,NA,10047895,Weight decreased,10022891,Investigations,Inv,fexofenadine,DB00950
,4688,DB01098,10047895,184,7965,166,7043,0.870974674,0.980122613,0.788283673,1.219405935,0.942937078,DB0109810047895_,0.058755724,-0.0200776,NA,10047895,Weight decreased,10022891,Investigations,Inv,rosuvastatin,DB01098
,4696,DB00181,10063856,80,9776,89,5782,5.61346233875607e-05,0.531645781,0.387401333,0.728653755,0.000487446,DB0018110063856_,7.626331359,-0.631777837,NA,10063856,Implant site extravasation,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,4703,DB00181,10064684,88,9768,47,5824,0.592248318,1.116361212,0.773563547,1.628935222,0.738465935,DB0018110064684_,0.303180305,0.110074478,NA,10064684,Device dislocation,10077536,Product issues,Prod,baclofen,DB00181
,4717,DB00811,10013709,133,2665,281,3875,0.0005227,0.688244599,0.552354281,0.854212225,0.003202229,DB0081110013709_,5.74390829,-0.373610982,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,4718,DB06403,10013709,301,21170,143,6518,3.76668679927478e-05,0.648084477,0.528276418,0.798064673,0.000346664,DB0640310013709_,7.967153293,-0.433734226,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,4719,DB00811,10019744,79,2719,240,3916,3.7995731150558e-09,0.474128152,0.361176049,0.616905675,9.36005429514918e-08,DB0081110019744_,16.18422965,-0.74627763,NA,10019744,Hepatitis C,10021881,Infections and infestations,Infec,ribavirin,DB00811
,4722,DB06403,10040047,220,21251,61,6600,0.480697022,1.12009615,0.838756049,1.515062413,0.645472348,DB0640310040047_,0.437772907,0.11341453,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,4728,DB00030,10013968,103,2103,56,1765,0.0115158,1.543504385,1.09687298,2.191052538,0.039862094,DB0003010013968_,3.222329437,0.434055406,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin human,DB00030
,4733,DB14512,10069293,149,4695,82,2330,0.477974758,0.901780152,0.680834479,1.20126628,0.643286259,DB1451210069293_,0.441165461,-0.103384522,NA,10069293,Product container issue,10077536,Product issues,Prod,mometasone furoate,DB14512
,4735,DB00051,10020751,400,25331,94,11326,4.16009247100559e-09,1.902609813,1.514485706,2.410778552,1.01719098232914e-07,DB0005110020751_,16.10105076,0.643226529,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,adalimumab,DB00051
,4736,DB00051,10037844,1159,24572,422,10998,0.000325141,1.2292269,1.096082562,1.380555847,0.002154898,DB0005110037844_,6.140011795,0.206385435,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,4737,DB08880,10020937,219,3119,37,772,0.034303923,1.464877433,1.02003601,2.15495556,0.094012993,DB0888010020937_,2.364322278,0.381771575,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,teriflunomide,DB08880
,4738,DB00005,10027175,984,127098,281,42138,0.028694722,1.160974161,1.015317832,1.330922051,0.081818168,DB0000510027175_,2.503255963,0.149259447,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,4739,DB00381,10013786,169,29191,93,22794,0.007168983,1.418965597,1.09459148,1.84907348,0.027300281,DB0038110013786_,3.600858277,0.349928153,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,4740,DB00722,10013786,109,25294,83,25949,0.042858714,1.347247199,1.002793113,1.81567174,0.11143944,DB0072210013786_,2.194273972,0.298063399,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,4741,DB00999,10013786,138,21292,53,12186,0.01276232,1.490194588,1.07730889,2.087883053,0.04324579,DB0099910013786_,3.140855388,0.398906707,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,4742,DB01101,10013786,192,7397,44,3864,2.11567049653007e-07,2.279308274,1.631047159,3.247025596,3.57049110762715e-06,DB0110110013786_,12.54280741,0.823872009,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,capecitabine,DB01101
,4743,DB00999,10023232,248,21182,75,12164,4.86753472558968e-07,1.898855455,1.459600599,2.494977689,7.57284109275671e-06,DB0099910023232_,11.79094225,0.641251312,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,4745,DB00381,10029331,338,29022,270,22617,0.773604812,0.975567353,0.828069242,1.150210028,0.876342038,DB0038110029331_,0.13199881,-0.024736076,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,4746,DB00722,10029331,237,25166,243,25789,1,0.999453023,0.831427647,1.201306881,1,DB0072210029331_,0,-0.000547127,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,4747,DB00999,10029331,242,21188,153,12086,0.318120754,0.902233646,0.732895937,1.113455358,0.486109369,DB0099910029331_,0.721321641,-0.102881761,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,4748,DB01101,10029331,206,7383,110,3798,0.763508189,0.963403499,0.757992813,1.229824523,0.869061935,DB0110110029331_,0.140340884,-0.037282953,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,capecitabine,DB01101
,4749,DB00381,10043607,250,29110,207,22680,0.538277321,0.940978127,0.778839367,1.137759694,0.694240401,DB0038110043607_,0.364936979,-0.060835384,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,4750,DB00722,10043607,172,25231,185,25847,0.671020261,0.952414562,0.768735082,1.179499307,0.800371966,DB0072210043607_,0.222678702,-0.048754875,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,lisinopril,DB00722
,4751,DB00999,10043607,147,21283,108,12131,0.049819726,0.775836039,0.600408455,1.005066567,0.12469807,DB0099910043607_,2.081859907,-0.253814071,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,hydrochlorothiazide,DB00999
,4752,DB01101,10043607,48,7541,35,3873,0.130198867,0.704351902,0.44535835,1.12403214,0.256005178,DB0110110043607_,1.362557609,-0.350477187,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,capecitabine,DB01101
,4753,DB00126,10044390,44,10127,22,5923,0.610234392,1.169764602,0.68541338,2.051573214,0.752398667,DB0012610044390_,0.284488953,0.156802534,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,4754,DB00169,10044390,115,38576,53,18122,0.934199032,1.019332562,0.729687164,1.44007713,0.974730929,DB0016910044390_,0.025593817,0.019148062,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,4755,DB00787,10044390,44,16956,35,17213,0.311232298,1.276184765,0.799686521,2.050617129,0.478741863,DB0078710044390_,0.736593734,0.243874975,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,4756,DB01076,10044390,121,25626,130,25453,0.569151914,0.924510738,0.715250257,1.194203727,0.720138542,DB0107610044390_,0.328311666,-0.078490613,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,4757,DB01373,10044390,68,22652,27,7354,0.402767473,0.817630894,0.516048431,1.329709435,0.572519429,DB0137310044390_,0.557708606,-0.201344274,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,calcium,DB01373
,4760,DB00203,10013709,218,13660,721,8217,9.65081374094813e-127,0.181893901,0.155209303,0.212479997,2.67022778085075e-123,DB0020310013709_,282.2358027,-1.704331725,male,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,4761,DB00381,10013709,1075,28285,765,22122,0.049869408,1.099076583,0.999075984,1.209410297,0.124780981,DB0038110013709_,2.081195232,0.094470357,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,4764,DB06700,10013573,120,2105,23,595,0.096614456,1.474534542,0.928083478,2.437630981,0.205706354,DB0670010013573_,1.581305591,0.388342376,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,desvenlafaxine,DB06700
,4765,DB00641,10027599,61,14063,17,12458,6.15555291311727e-06,3.178418124,1.831424837,5.808038557,7.09176893803583e-05,DB0064110027599_,9.553990658,1.156383628,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,4772,DB00412,10035598,118,946,151,1235,0.896358519,1.020187281,0.783005565,1.326888392,0.956301489,DB0041210035598_,0.044682051,0.019986219,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosiglitazone,DB00412
,4774,DB00186,10001052,47,16854,16,9992,0.066734395,1.741480847,0.969092325,3.292219021,0.15544451,DB0018610001052_,1.861466463,0.554735813,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,4795,DB00264,10016173,1019,28588,736,24156,0.001415236,1.169866053,1.061327276,1.28996042,0.007324174,DB0026410016173_,4.916574877,0.156889257,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,4796,DB00381,10016173,906,28454,474,22413,5.01551332336517e-13,1.505574771,1.343849377,1.688370472,2.33539003905498e-11,DB0038110016173_,24.48025711,0.409174733,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,4797,DB00413,10016173,132,2067,66,1141,0.54128274,1.103999274,0.807780667,1.520683562,0.696646762,DB0041310016173_,0.361476795,0.09893929,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,pramipexole,DB00413
,4798,DB00451,10016173,1589,45682,449,14970,0.00603452,1.15971682,1.04197145,1.292766098,0.023771804,DB0045110016173_,3.739255101,0.148175855,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,4799,DB00641,10016173,501,13623,391,12084,0.065329395,1.136571253,0.991480412,1.303636884,0.152994591,DB0064110016173_,1.877352709,0.128016058,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,4800,DB01104,10016173,523,14940,255,7031,0.667180962,0.965246319,0.827131922,1.128610685,0.797782349,DB0110410016173_,0.225919465,-0.035371958,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,4801,DB01156,10016173,365,13257,145,6183,0.111718191,1.174006117,0.963510904,1.436546963,0.228646941,DB0115610016173_,1.475576209,0.160421931,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,4802,DB00264,10018870,28,29579,60,24832,2.34623896990944e-05,0.391778697,0.240715508,0.62353622,0.000228877,DB0026410018870_,8.382326081,-0.937058147,NA,10018870,Blood urine present,10022891,Investigations,Inv,metoprolol,DB00264
,4803,DB00381,10018870,16,29344,46,22841,1.97653200257769e-06,0.27075008,0.143009749,0.487390514,2.61992656014899e-05,DB0038110018870_,10.54977918,-1.306559097,male,10018870,Blood urine present,10022891,Investigations,Inv,amlodipine,DB00381
,4805,DB00451,10018870,48,47223,31,15388,0.003809461,0.504536485,0.314545594,0.820320511,0.016397559,DB0045110018870_,4.110622816,-0.684115122,NA,10018870,Blood urine present,10022891,Investigations,Inv,levothyroxine,DB00451
,4809,DB00264,10022437,474,29133,310,24582,0.000520948,1.290167394,1.114560699,1.495133333,0.003193729,DB0026410022437_,5.746566029,0.254771973,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,4810,DB00381,10022437,505,28855,272,22615,5.65882066867702e-07,1.455104609,1.251843541,1.694258115,8.66290630612554e-06,DB0038110022437_,11.65646029,0.375077794,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,4811,DB00413,10022437,57,2142,38,1169,0.3841769,0.818688821,0.530088813,1.276884614,0.554235619,DB0041310022437_,0.590165378,-0.200051217,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,pramipexole,DB00413
,4812,DB00641,10022437,233,13891,163,12312,0.022372681,1.266948462,1.031115379,1.559711276,0.067454224,DB0064110022437_,2.69630608,0.236611224,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,4813,DB01104,10022437,327,15136,131,7155,0.116922284,1.179957397,0.958637916,1.459273878,0.236498824,DB0110410022437_,1.441812041,0.165478333,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,4814,DB01156,10022437,306,13316,129,6199,0.375947067,1.104272182,0.893942643,1.370383611,0.545743009,DB0115610022437_,0.605607094,0.099186459,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,4815,DB06605,10049414,58,14015,54,12979,1,0.994677591,0.674118518,1.469736026,1,DB0660510049414_,0,-0.005336624,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,4818,DB00051,10028596,103,25628,118,11302,2.4653290331172e-12,0.38495237,0.292364332,0.506197494,1.04098270900378e-10,DB0005110028596_,22.98568575,-0.954635667,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,adalimumab,DB00051
,4820,DB00043,10013968,398,6015,123,2177,0.151122328,1.171090154,0.94839587,1.454166739,0.285424328,DB0004310013968_,1.253778334,0.15793507,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omalizumab,DB00043
,4822,DB00005,10035598,69,128013,27,42392,0.478668185,0.846312605,0.535116485,1.374114737,0.643915824,DB0000510035598_,0.44018727,-0.166866478,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,4823,DB00112,10037660,167,5766,105,3986,0.491562939,1.099499827,0.853205803,1.422089256,0.654645177,DB0011210037660_,0.423661904,0.094855374,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,4824,DB00619,10037660,40,2859,29,2465,0.543975407,1.189188304,0.716658484,1.995305552,0.699068305,DB0061910037660_,0.358006824,0.173270977,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,4834,DB01164,10011906,407,6117,565,7371,0.035555918,0.868037161,0.758838069,0.992311721,0.09659817,DB0116410011906_,2.337195485,-0.141520753,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,4835,DB01164,10025482,85,6439,101,7835,0.882324631,1.024048046,0.756740061,1.382977647,0.950859822,DB0116410025482_,0.050388628,0.023763445,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,4836,DB00181,10016825,122,9734,34,5837,3.93954533095535e-05,2.151590519,1.458488262,3.251260511,0.000359927,DB0018110016825_,7.929609797,0.766207345,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,baclofen,DB00181
,4837,DB00181,10028347,41,9815,29,5842,0.535987965,0.84152206,0.509815472,1.405689089,0.692408889,DB0018110028347_,0.367578618,-0.172543051,NA,10028347,Muscle twitching,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,4838,DB00181,10028813,518,9338,205,5666,2.33249663983333e-07,1.533158734,1.297150316,1.817420445,3.90134738644729e-06,DB0018110028813_,12.45418858,0.427330139,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,baclofen,DB00181
,4839,DB00181,10037087,224,9632,125,5746,0.57604665,1.069026659,0.852911344,1.344784515,0.725422742,DB0018110037087_,0.321000701,0.06674857,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,baclofen,DB00181
,4840,DB00181,10047700,301,9555,143,5728,0.025027862,1.26179253,1.027742127,1.555035022,0.073516638,DB0018110047700_,2.610243534,0.232533353,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,baclofen,DB00181
,4841,DB00635,10003553,403,32650,113,23681,1.23760902923732e-21,2.586613471,2.093111524,3.217905843,1.52725602504709e-19,DB0063510003553_,43.32564409,0.95034948,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,4842,DB01222,10003553,345,8929,107,5298,1.6197986907473e-09,1.913049597,1.531417658,2.405825455,4.3180941771088e-08,DB0122210003553_,16.9578666,0.648698616,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,4843,DB00635,10053762,1221,31832,897,22897,0.637469064,0.979117749,0.896016867,1.070268691,0.774766465,DB0063510053762_,0.25519363,-0.021103369,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,4844,DB01222,10053762,354,8920,182,5223,0.171131565,1.138920756,0.946545591,1.374019445,0.312398535,DB0122210053762_,1.16347555,0.130081109,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,budesonide,DB01222
,4846,DB01222,10064385,45,9229,24,5381,0.802892838,1.093230179,0.651211768,1.878181475,0.893342905,DB0122210064385_,0.11278478,0.089136781,NA,10064385,Circumstance or information capable of leading to medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,budesonide,DB01222
,4847,DB06643,10000059,188,52233,33,7482,0.264267425,0.816053237,0.560944697,1.221042492,0.426177635,DB0664310000059_,0.852899035,-0.203275685,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,4848,DB06643,10003988,1522,50899,159,7356,7.32561474870891e-05,1.383399189,1.171897284,1.642335276,0.000610017,DB0664310003988_,7.402024135,0.324543651,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,4850,DB06643,10013781,113,52308,15,7500,0.893837882,1.080150835,0.627439349,1.994705492,0.95581177,DB0664310013781_,0.045194278,0.077100693,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,4851,DB06643,10017885,168,52253,16,7499,0.145808758,1.506879657,0.900556229,2.698666172,0.278190418,DB0664310017885_,1.279449442,0.41004106,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,4852,DB06643,10020642,82,52339,17,7498,0.170348326,0.691018548,0.406101868,1.243877815,0.311334011,DB0664310020642_,1.166888954,-0.369588614,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,4854,DB06643,10028334,516,51905,50,7465,0.006065674,1.484217333,1.10761612,2.028276688,0.023873063,DB0664310028334_,3.735004536,0.394887585,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,4855,DB06643,10047895,316,52105,93,7422,1.21721682835034e-08,0.484002852,0.382439959,0.617481625,2.6886171708562e-07,DB0664310047895_,15.12906865,-0.72566448,NA,10047895,Weight decreased,10022891,Investigations,Inv,denosumab,DB06643
,4856,DB06643,10060800,135,52286,55,7460,1.65340344428716e-09,0.350215308,0.253877731,0.488825035,4.39208787600687e-08,DB0664310060800_,16.94087603,-1.049207149,male,10060800,Hot flush,10047065,Vascular disorders,Vasc,denosumab,DB06643
,4857,DB06643,10061428,209,52212,102,7413,1.04902834446644e-20,0.290943095,0.228207769,0.372845884,1.1813730445513e-18,DB0664310061428_,41.27985431,-1.234627582,male,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,denosumab,DB06643
,4858,DB06643,10068789,276,52145,16,7499,8.55223776791018e-05,2.480707951,1.499386322,4.403835994,0.00069834,DB0664310068789_,7.266804807,0.908543984,NA,10068789,Bone density abnormal,10022891,Investigations,Inv,denosumab,DB06643
,4860,DB00005,10037867,296,127786,108,42311,0.387712415,0.907471551,0.725413306,1.142275997,0.557709234,DB0000510037867_,0.583917538,-0.097093062,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,4861,DB00694,10021097,64,570,51,720,0.019016081,1.584586436,1.061030815,2.376554642,0.059405478,DB0069410021097_,2.823368843,0.46032345,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,daunorubicin,DB00694
,4864,DB00694,10038695,32,602,35,736,0.706486347,1.117707717,0.661331821,1.883407921,0.824280184,DB0069410038695_,0.193244778,0.111279906,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,daunorubicin,DB00694
,4865,DB00987,10038695,66,2038,121,2807,0.069830169,0.751313598,0.544922731,1.028351171,0.160981709,DB0098710038695_,1.826464529,-0.285932141,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cytarabine,DB00987
,4866,DB00694,10040047,47,587,60,711,0.840133385,0.94882985,0.623318469,1.437348059,0.918209427,DB0069410040047_,0.08532978,-0.05252579,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,daunorubicin,DB00694
,4868,DB00412,10048858,47,1017,104,1282,0.001656511,0.569807228,0.39089673,0.82035899,0.008332485,DB0041210048858_,4.787593542,-0.562457172,NA,10048858,Ischaemic cardiomyopathy,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,4869,DB01261,10028596,30,3751,43,3260,0.044282293,0.606399491,0.366403835,0.991865791,0.1141641,DB0126110028596_,2.170118392,-0.500216284,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,sitagliptin,DB01261
,4871,DB00060,10043607,75,9433,15,2450,0.432286765,1.298601294,0.737768802,2.439134092,0.600722052,DB0006010043607_,0.509622927,0.261287757,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,interferon beta-1a,DB00060
,4872,DB00108,10043607,46,10148,27,3268,0.019224235,0.548691091,0.333393959,0.919429765,0.059934648,DB0010810043607_,2.814500504,-0.600219672,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,natalizumab,DB00108
,4873,DB00108,10016173,456,9738,149,3146,0.92286733,0.988707401,0.816256561,1.203013775,0.966263728,DB0010810016173_,0.034318472,-0.011356844,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,natalizumab,DB00108
,4874,DB06637,10016173,571,5591,178,1841,0.563445571,1.056275926,0.883559055,1.267363131,0.715372717,DB0663710016173_,0.334951589,0.054749445,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,dalfampridine,DB06637
,4875,DB00108,10048334,147,10047,52,3243,0.561417323,0.912478695,0.659073509,1.280568341,0.713805322,DB0010810048334_,0.337145012,-0.091590542,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,natalizumab,DB00108
,4876,DB06637,10048334,104,6058,43,1976,0.209204059,0.788924605,0.545766301,1.157707431,0.360242962,DB0663710048334_,1.020976582,-0.23708452,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,dalfampridine,DB06637
,4880,DB00186,10001497,155,16746,191,9817,1.08411283530926e-11,0.475741443,0.381814978,0.592063592,4.1208829900367e-10,DB0018610001497_,21.60978347,-0.74288076,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,4881,DB00422,10001497,23,3412,94,2855,2.79571107247006e-14,0.204755034,0.123493452,0.326885248,1.54705822189212e-12,DB0042210001497_,27.19466591,-1.585940969,male,10001497,Agitation,10037175,Psychiatric disorders,Psych,methylphenidate,DB00422
,4882,DB00829,10001497,44,8008,61,4393,2.86388686892232e-06,0.395723687,0.261799054,0.593887025,3.64009992019455e-05,DB0082910001497_,10.22091433,-0.927039071,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,4883,DB00996,10001497,154,38799,136,22289,0.000300213,0.650540703,0.512810014,0.825892234,0.002018798,DB0099610001497_,6.205252973,-0.429951411,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,4884,DB00186,10013709,820,16081,448,9560,0.161985889,1.088139933,0.96582716,1.227104272,0.300044182,DB0018610013709_,1.203825541,0.084469755,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,4885,DB00422,10013709,336,3099,367,2582,0.000750647,0.76283368,0.649881097,0.895189058,0.004335474,DB0042210013709_,5.440924218,-0.270715253,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,4886,DB00829,10013709,435,7617,221,4233,0.295408901,1.09386394,0.924017487,1.297753138,0.461307554,DB0082910013709_,0.773690313,0.089716327,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,4887,DB00996,10013709,2136,36817,1017,21408,2.62450772999401e-07,1.221223011,1.130697168,1.319727541,4.33460167658766e-06,DB0099610013709_,12.34888084,0.199852824,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,4891,DB00996,10015535,40,38913,36,22389,0.056295678,0.639323595,0.397122605,1.032498833,0.136632677,DB0099610015535_,1.990459147,-0.447344544,NA,10015535,Euphoric mood,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,4892,DB00186,10041349,262,16639,179,9829,0.13652572,0.864639702,0.711015965,1.05333531,0.264847222,DB0018610041349_,1.328602142,-0.145442388,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,4893,DB00422,10041349,65,3370,75,2874,0.086285501,0.739150362,0.519900893,1.048496666,0.188835968,DB0042210041349_,1.666876534,-0.302253912,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,methylphenidate,DB00422
,4894,DB00829,10041349,153,7899,75,4379,0.403061364,1.130930781,0.850184806,1.515288896,0.572828762,DB0082910041349_,0.557168451,0.123040994,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,4895,DB00996,10041349,737,38216,363,22062,0.013735503,1.172118907,1.031088499,1.334214265,0.045840237,DB0099610041349_,3.082593037,0.158813143,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,4896,DB00186,10042458,160,16741,73,9935,0.06608308,1.300707002,0.979052736,1.741956087,0.154306987,DB0018610042458_,1.868811236,0.262907964,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,4897,DB00422,10042458,104,3331,51,2898,0.000786441,1.773976721,1.252047972,2.54101394,0.004509513,DB0042210042458_,5.401566134,0.573223761,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,methylphenidate,DB00422
,4898,DB00829,10042458,90,7962,47,4407,0.788319698,1.059901247,0.735303907,1.545120874,0.885341847,DB0082910042458_,0.12178144,0.058175741,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,4899,DB00996,10042458,284,38669,127,22298,0.017990189,1.289493601,1.041722844,1.6034823,0.056845839,DB0099610042458_,2.867412251,0.254249584,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,4905,DB00422,10069326,65,3370,94,2855,0.001206759,0.585873466,0.418639731,0.815774934,0.006433356,DB0042210069326_,5.046258911,-0.534651441,NA,10069326,Product substitution issue,10077536,Product issues,Prod,methylphenidate,DB00422
,4907,DB00996,10069326,45,38908,27,22398,0.902709995,0.959465739,0.582394352,1.608590975,0.957245878,DB0099610069326_,0.043694994,-0.041378671,NA,10069326,Product substitution issue,10077536,Product issues,Prod,gabapentin,DB00996
,4908,DB00186,10069327,52,16849,25,9983,0.411330953,1.232422737,0.750523372,2.074013228,0.580708307,DB0018610069327_,0.543506702,0.208981937,NA,10069327,Product quality issue,10077536,Product issues,Prod,lorazepam,DB00186
,4909,DB00422,10069327,65,3370,111,2838,7.27321408029876e-06,0.493203098,0.355895057,0.678762055,8.20499708586493e-05,DB0042210069327_,9.408182096,-0.706834227,NA,10069327,Product quality issue,10077536,Product issues,Prod,methylphenidate,DB00422
,4910,DB00829,10069327,43,8009,23,4431,1,1.034340592,0.608705379,1.800523301,1,DB0082910069327_,0,0.033764115,NA,10069327,Product quality issue,10077536,Product issues,Prod,diazepam,DB00829
,4911,DB00996,10069327,130,38823,64,22361,0.331890158,1.169972128,0.860432807,1.604695751,0.500702107,DB0099610069327_,0.691743951,0.156979927,NA,10069327,Product quality issue,10077536,Product issues,Prod,gabapentin,DB00996
,4912,DB00186,10074903,85,16816,34,9974,0.056993492,1.482793042,0.984528142,2.278809803,0.137760259,DB0018610074903_,1.98224036,0.3939275,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,4913,DB00422,10074903,32,3403,28,2921,1,0.980982186,0.570624286,1.695313607,1,DB0042210074903_,0,-0.019200979,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,methylphenidate,DB00422
,4914,DB00829,10074903,103,7949,67,4387,0.295724062,0.848452156,0.616298478,1.174673215,0.46153111,DB0082910074903_,0.773205816,-0.164341582,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,4915,DB00996,10074903,299,38654,118,22307,0.000418287,1.462289157,1.177002372,1.826505573,0.002658145,DB0099610074903_,5.93012669,0.380003124,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,4916,DB00783,10013709,1215,15499,27,346,1,1.004580686,0.674979857,1.553307003,1,DB0078310013709_,0,0.004570227,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,estradiol,DB00783
,4920,DB00331,10011078,135,24811,248,20504,2.62258468373577e-14,0.449863747,0.361771324,0.557504618,1.45739193260031e-12,DB0033110011078_,27.25437263,-0.798810527,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,metformin,DB00331
,4925,DB00412,10011077,15,1049,37,1349,0.033991871,0.521480838,0.26436448,0.979590556,0.093386604,DB0041210011077_,2.371007371,-0.65108275,NA,10011077,Coronary artery bypass,10042613,Surgical and medical procedures,Surg,rosiglitazone,DB00412
,4926,DB01175,10046735,92,10632,20,4872,0.001472616,2.107814773,1.287379821,3.614828502,0.007574151,DB0117510046735_,4.883013964,0.745651758,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,escitalopram,DB01175
,4929,DB01275,10030095,36,3943,27,3322,0.704065242,1.123302844,0.661662122,1.928223843,0.822564291,DB0127510030095_,0.195328634,0.116273314,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,4930,DB01275,10037087,73,3906,49,3300,0.233956288,1.258619719,0.86173559,1.852077875,0.39076959,DB0127510037087_,0.939637178,0.230015659,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,hydralazine,DB01275
,4932,DB01275,10037844,88,3891,70,3279,0.74722376,1.059419472,0.762376042,1.476791185,0.856161658,DB0127510037844_,0.155296067,0.05772109,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,hydralazine,DB01275
,4941,DB00811,10033295,18,2780,44,4112,0.089982484,0.605143437,0.328375877,1.071588813,0.195155708,DB0081110033295_,1.633957539,-0.502289763,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,ribavirin,DB00811
,4945,DB00331,10035664,594,24352,558,20194,0.038624738,0.882758062,0.783873106,0.994204201,0.102873124,DB0033110035664_,2.274258852,-0.124704111,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,metformin,DB00331
,4947,DB00331,10038435,181,24765,247,20505,3.47335556827167e-07,0.606755546,0.497604681,0.738702456,5.57539854119211e-06,DB0033110038435_,12.09714676,-0.499629294,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,4952,DB00005,10072970,137,127945,36,42383,0.252377333,1.260616111,0.867656329,1.874440769,0.412494602,DB0000510072970_,0.885532159,0.231600578,NA,10072970,Meniscus injury,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,4953,DB01268,10003549,154,1989,236,2894,0.668310413,0.949452028,0.763670102,1.177925071,0.798507747,DB0126810003549_,0.225010609,-0.051870273,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,4954,DB01268,10013781,68,2075,54,3076,0.000739573,1.866457159,1.28055964,2.731959189,0.004282339,DB0126810013781_,5.453256019,0.624042067,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,4955,DB01268,10013786,69,2074,115,3015,0.401215696,0.872275589,0.634111914,1.192452152,0.571048729,DB0126810013786_,0.560280733,-0.136649862,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,sunitinib,DB01268
,4956,DB01268,10053762,46,2097,49,3081,0.139662135,1.37917731,0.898235322,2.114535295,0.269343646,DB0126810053762_,1.31176722,0.321487169,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sunitinib,DB01268
,4957,DB08908,10020751,190,10483,24,3255,6.41910189240796e-06,2.458141339,1.59948492,3.939258784,7.35831195996263e-05,DB0890810020751_,9.517094912,0.899405511,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,dimethyl fumarate,DB08908
,4960,DB00404,10010264,387,19505,100,9762,7.4504469797864e-10,1.936846046,1.548480936,2.441410274,2.12172263124253e-08,DB0040410010264_,17.66845242,0.661060901,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,4961,DB01255,10010264,71,2062,53,1525,1,0.990750189,0.679872209,1.451340422,1,DB0125510010264_,0,-0.009292856,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,lisdexamfetamine,DB01255
,4962,DB06700,10010264,85,2140,8,610,0.001210098,3.02787024,1.458019339,7.280260801,0.006446305,DB0670010010264_,5.044248244,1.107859481,female,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,desvenlafaxine,DB06700
,4967,DB00482,10017577,153,8106,44,3027,0.145323207,1.298456969,0.920469351,1.864568662,0.277512478,DB0048210017577_,1.281889383,0.261176612,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,4968,DB00736,10017577,126,10465,47,5506,0.044435884,1.410460414,0.999724653,2.019369767,0.11447025,DB0073610017577_,2.167440312,0.343916186,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,4969,DB00482,10023232,109,8150,25,3046,0.030944716,1.629512336,1.045055835,2.632997903,0.086807029,DB0048210023232_,2.444067677,0.488280789,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,4970,DB00736,10023232,95,10496,28,5525,0.005660492,1.785911023,1.159419183,2.831919598,0.022596407,DB0073610023232_,3.789964347,0.579928662,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,4971,DB00482,10033371,534,7725,128,2943,2.09122227051133e-06,1.589304049,1.301659934,1.952060005,2.75804201607578e-05,DB0048210033371_,10.49840445,0.463296215,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,4972,DB00736,10033371,428,10163,133,5420,2.97506860028101e-08,1.716152841,1.405306884,2.106814321,6.01535985833742e-07,DB0073610033371_,14.32377948,0.540085065,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,4973,DB00199,10013700,1875,835,211,489,3.1138427934825e-78,5.201256776,4.327659074,6.266091193,4.09236789133437e-75,DB0019910013700_,171.2847582,1.648900284,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,erythromycin,DB00199
,4974,DB00295,10013700,4868,9795,1250,8352,1.14189430742025e-292,3.320523497,3.098833083,3.559519146,3.00146918705413e-288,DB0029510013700_,662.0454049,1.20012245,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,morphine,DB00295
,4975,DB00316,10013700,2701,62773,546,36407,1.12790701732813e-133,2.869043894,2.613586781,3.154328768,3.95293812672933e-130,DB0031610013700_,297.961603,1.053978836,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,acetaminophen,DB00316
,4976,DB00454,10013700,1504,463,234,367,6.17249926433245e-63,5.090838355,4.175249339,6.216993566,5.79443368439208e-60,DB0045410013700_,136.3982078,1.627442523,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,meperidine,DB00454
,4978,DB00537,10013700,1635,5922,286,4012,2.63793123125143e-112,3.872316305,3.39108298,4.434077168,5.54704179307552e-109,DB0053710013700_,249.2685104,1.353852856,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ciprofloxacin,DB00537
,4979,DB00813,10013700,495,10077,158,10010,8.27397396421104e-40,3.112026594,2.590527004,3.754530345,3.22194675035981e-37,DB0081310013700_,84.02566268,1.135274152,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,fentanyl,DB00813
,4981,DB01211,10013700,534,1118,54,733,7.54463036794458e-50,6.479095625,4.808826345,8.874193079,4.45641818475108e-47,DB0121110013700_,106.727154,1.868580937,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,clarithromycin,DB01211
,4984,DB01164,10046571,65,6459,39,7897,0.000478896,2.037599542,1.347421049,3.117509772,0.002980767,DB0116410046571_,5.815574501,0.71177242,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,calcium chloride,DB01164
,4985,DB00243,10021097,47,1207,35,1591,0.012634054,1.76968849,1.110604275,2.84360904,0.042899638,DB0024310021097_,3.148891881,0.570803537,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ranolazine,DB00243
,4986,DB00381,10021097,765,28595,664,22223,0.042591162,0.895379953,0.804668752,0.996477656,0.110897343,DB0038110021097_,2.199150341,-0.110507123,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,4987,DB00993,10003239,93,3156,49,1570,0.786337381,0.9441805,0.657253358,1.370727643,0.884078792,DB0099310003239_,0.12320909,-0.057437923,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,azathioprine,DB00993
,4988,DB06273,10003239,147,4948,33,1377,0.312736494,1.239630765,0.840545891,1.87656403,0.480254652,DB0627310003239_,0.73343879,0.214813565,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tocilizumab,DB06273
,4989,DB00993,10010264,93,3156,23,1596,0.001850279,2.044538249,1.27823892,3.396393021,0.009127257,DB0099310010264_,4.696490086,0.715171969,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,azathioprine,DB00993
,4990,DB06273,10010264,57,5038,24,1386,0.101954907,0.653432514,0.397373389,1.105254257,0.213877473,DB0627310010264_,1.542351984,-0.42551602,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,4994,DB06273,10023232,63,5032,24,1386,0.189828556,0.723062257,0.443476518,1.21487378,0.336297337,DB0627310023232_,1.089759578,-0.324259951,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,tocilizumab,DB06273
,4995,DB00005,10024690,174,127908,64,42355,0.499416449,0.90026565,0.672156226,1.218863299,0.66121802,DB0000510024690_,0.413671659,-0.105065393,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,etanercept,DB00005
,4998,DB00993,10033425,53,3196,16,1603,0.093421215,1.661274623,0.931658615,3.12381385,0.200797138,DB0099310033425_,1.605460146,0.507585153,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,azathioprine,DB00993
,4999,DB06273,10033425,85,5010,16,1394,0.180179334,1.478069342,0.85639706,2.711459551,0.324040492,DB0627310033425_,1.126886797,0.390736738,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,tocilizumab,DB06273
,5002,DB00005,10060933,701,127381,240,42179,0.650168773,0.967158457,0.833742678,1.125021927,0.784884662,DB0000510060933_,0.242218499,-0.033392933,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,5005,DB08908,10002855,110,10563,38,3241,0.558567334,0.888171846,0.60771708,1.32338889,0.7114723,DB0890810002855_,0.340418794,-0.118590034,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,dimethyl fumarate,DB08908
,5006,DB08908,10048393,822,9851,259,3020,0.708922228,0.97296896,0.839938804,1.129841878,0.826298175,DB0890810048393_,0.190799584,-0.027403099,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,5008,DB00722,10022061,174,25229,47,25985,3.06117487732839e-19,3.812602085,2.746992341,5.38310459,2.97460190944831e-17,DB0072210022061_,38.05383636,1.338311918,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,5009,DB00153,10022093,80,7343,7,3432,1.78770541237476e-07,5.341364345,2.472451861,13.72834543,3.06822309920147e-06,DB0015310022093_,12.69441196,1.675481116,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,5011,DB00722,10022093,107,25296,31,26001,1.52717904781964e-11,3.548107101,2.358516176,5.479468649,5.64645776737499e-10,DB0072210022093_,21.29482253,1.26641425,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,5013,DB00722,10022095,106,25297,52,25980,9.59335160252152e-06,2.093457023,1.487839892,2.977513818,0.000104914,DB0072210022095_,9.162367815,0.738816778,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,5016,DB00722,10053425,90,25313,32,26000,5.07025262547018e-08,2.888870547,1.909551021,4.471952505,9.78858540290002e-07,DB0072210053425_,13.8368787,1.060865612,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,5022,DB00065,10060795,53,9411,25,4932,0.720915102,1.111009988,0.677400148,1.868202432,0.835410838,DB0006510060795_,0.179831654,0.1052695,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,infliximab,DB00065
,5024,DB00188,10062355,161,7725,225,8603,0.030276462,0.79689534,0.64528338,0.982341923,0.085287409,DB0018810062355_,2.461728441,-0.227031927,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,5025,DB01234,10035226,1318,30307,1588,31300,5.22646834197609e-05,0.85717156,0.79480983,0.924284673,0.000458767,DB0123410035226_,7.686968523,-0.154117194,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,5026,DB00005,10016766,100,127982,34,42385,0.920377388,0.974055921,0.65402933,1.483184137,0.964788479,DB0000510016766_,0.035846395,-0.026286564,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,5027,DB00005,10023003,101,127981,20,42399,0.034984447,1.672953538,1.028162371,2.855016273,0.095385737,DB0000510023003_,2.349826218,0.51459065,NA,10023003,Irritable bowel syndrome,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,5028,DB00588,10017955,94,16430,97,8371,1.55809236026712e-06,0.493738882,0.36732782,0.663440658,2.13082506189496e-05,DB0058810017955_,10.75641621,-0.70574848,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,5029,DB06228,10017955,1885,14027,2121,13955,0.000280646,0.884174034,0.826933015,0.945340737,0.001912071,DB0622810017955_,6.259568566,-0.123101364,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,5030,DB01222,10047899,159,9115,48,5357,3.12617577342003e-05,1.946715542,1.398850945,2.75273708,0.000294311,DB0122210047899_,8.130874756,0.666143615,NA,10047899,Weight increased,10022891,Investigations,Inv,budesonide,DB01222
,5031,DB01222,10074903,147,9127,70,5335,0.177857478,1.22745449,0.915351552,1.659376711,0.321139194,DB0122210074903_,1.135880623,0.204942505,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,budesonide,DB01222
,5032,DB00480,10035664,3591,63837,4389,63273,1.37705733148979e-19,0.810956328,0.774700469,0.848877165,1.37366041587132e-17,DB0048010035664_,38.82646757,-0.209541076,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,5033,DB00073,10003239,195,7211,95,6312,2.28204006764534e-06,1.796648907,1.395403779,2.326474388,2.97389306782636e-05,DB0007310003239_,10.42305357,0.585923212,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,rituximab,DB00073
,5034,DB00073,10061428,97,7309,104,6303,0.134640933,0.804333676,0.60226969,1.073354501,0.262121759,DB0007310061428_,1.338946155,-0.217741076,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,rituximab,DB00073
,5048,DB00264,10002034,610,28997,477,24415,0.242542609,1.076774479,0.952429776,1.217809475,0.400731188,DB0026410002034_,0.91446443,0.073969979,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,metoprolol,DB00264
,5049,DB00351,10002034,34,632,37,827,0.464015357,1.202294771,0.723106763,1.99362095,0.631247246,DB0035110002034_,0.460057661,0.18423204,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,megestrol acetate,DB00351
,5050,DB00497,10002034,293,18974,257,16118,0.730207489,0.968461362,0.815162535,1.151122391,0.843040535,DB0049710002034_,0.170740238,-0.032046692,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,oxycodone,DB00497
,5052,DB01115,10002034,78,3522,43,2225,0.509984359,1.14596082,0.776676342,1.710492419,0.670531919,DB0111510002034_,0.399683972,0.136243429,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,nifedipine,DB01115
,5053,DB01275,10002034,85,3894,96,3253,0.049360625,0.739702752,0.543730811,1.004869621,0.123825541,DB0127510002034_,2.08888163,-0.301506859,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,hydralazine,DB01275
,5055,DB00264,10005654,51,29556,23,24869,0.013711888,1.865711705,1.119332388,3.199961372,0.045787584,DB0026410005654_,3.083742325,0.623642591,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,metoprolol,DB00264
,5063,DB00264,10005724,162,29445,73,24819,5.2815540255817e-06,1.870484536,1.409703312,2.502242748,6.20449821508e-05,DB0026410005724_,9.687650917,0.626197507,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,metoprolol,DB00264
,5065,DB00497,10005724,75,19192,41,16334,0.024788554,1.556837558,1.049536845,2.338582936,0.07302927,DB0049710005724_,2.616894956,0.442656558,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,oxycodone,DB00497
,5071,DB00264,10018867,69,29538,134,24758,6.85360765551859e-09,0.431601571,0.317857392,0.581566433,1.59492764254366e-07,DB0026410018867_,15.65126728,-0.840252405,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,5073,DB00497,10018867,24,19243,42,16333,0.004293308,0.485029837,0.280812845,0.820031293,0.01809357,DB0049710018867_,4.012198679,-0.723544871,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,oxycodone,DB00497
,5087,DB00264,10038435,289,29318,291,24601,0.029357673,0.833347174,0.705056527,0.984946637,0.083283842,DB0026410038435_,2.485500727,-0.182304948,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,5089,DB00497,10038435,116,19151,143,16232,0.003198635,0.687561198,0.532976705,0.885387554,0.014256014,DB0049710038435_,4.25057641,-0.374604438,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,oxycodone,DB00497
,5090,DB00813,10038435,74,10498,66,10102,0.672264455,1.078880084,0.76277313,1.528821364,0.801035624,DB0081310038435_,0.221849859,0.075923544,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,fentanyl,DB00813
,5092,DB01115,10038435,42,3558,63,2205,1.02538480342478e-05,0.413215387,0.271753238,0.622754124,0.000110983,DB0111510038435_,9.106132853,-0.883786305,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,nifedipine,DB01115
,5093,DB01275,10038435,85,3894,92,3257,0.093226362,0.772806714,0.566412692,1.053432325,0.200470809,DB0127510038435_,1.607086635,-0.257726309,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,hydralazine,DB01275
,5111,DB00563,10011906,228,46418,135,15213,1.30287946884947e-07,0.553532023,0.445063539,0.690591695,2.31080882852283e-06,DB0056310011906_,12.97791295,-0.591435673,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,5112,DB00586,10011906,152,6957,96,2709,0.000340695,0.616570249,0.472477137,0.80783843,0.002242717,DB0058610011906_,6.100067274,-0.483583015,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,5113,DB00783,10051055,361,16353,7,366,0.85734433,1.154223194,0.54887322,2.912146847,0.931595523,DB0078310051055_,0.070856546,0.143427559,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,estradiol,DB00783
,5115,DB01373,10011781,114,22606,17,7364,0.001492788,2.184282553,1.304926219,3.88249456,0.007658423,DB0137310011781_,4.871949178,0.781287424,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,calcium,DB01373
,5119,DB01373,10017533,62,22658,11,7370,0.07526954,1.833231897,0.95646227,3.863298514,0.170285309,DB0137310017533_,1.770279963,0.606080473,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,calcium,DB01373
,5120,DB08895,10017533,154,27960,15,6631,0.000367931,2.434828715,1.429793509,4.459186974,0.002392646,DB0889510017533_,6.035355556,0.889876411,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,5122,DB00016,10011906,409,2353,332,1958,0.779816087,1.025122066,0.873860059,1.203142278,0.880132524,DB0001610011906_,0.127682787,0.024811694,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,5123,DB00635,10011906,849,32204,1181,22613,3.73222167543834e-51,0.504782667,0.460875945,0.552725119,2.28142899392783e-48,DB0063510011906_,109.6992825,-0.683627305,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,5124,DB00863,10011906,380,10293,308,5532,2.14613031998569e-07,0.663081489,0.567003986,0.775963315,3.61030626949272e-06,DB0086310011906_,12.53171795,-0.410857387,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,5125,DB01175,10011906,327,10397,309,4583,2.68228128698618e-20,0.466494287,0.396513422,0.548942594,2.84289369469483e-18,DB0117510011906_,40.40170923,-0.762509504,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,5126,DB01373,10011906,529,22191,348,7033,1.0562069052299e-23,0.481771167,0.418864921,0.554668875,1.50067018940367e-21,DB0137310011906_,47.94837515,-0.730286035,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,5127,DB00016,10018884,186,2576,174,2116,0.248736571,0.878102873,0.704426064,1.094993803,0.408130139,DB0001610018884_,0.896169188,-0.129991524,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,erythropoietin,DB00016
,5128,DB00169,10018884,391,38300,223,17952,0.021095499,0.82185836,0.694704603,0.974111176,0.064483071,DB0016910018884_,2.741352551,-0.196187211,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,5129,DB00480,10018884,1101,66327,910,66752,1.29160798926804e-05,1.21763876,1.113522448,1.331737301,0.000135963,DB0048010018884_,8.903129097,0.196913541,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,5130,DB00635,10018884,276,32777,250,23544,0.008760988,0.793022529,0.665284008,0.945603636,0.032030402,DB0063510018884_,3.441069763,-0.231903648,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,prednisone,DB00635
,5131,DB00863,10018884,108,10565,66,5774,0.474173249,0.894317327,0.651215812,1.236060502,0.639883142,DB0086310018884_,0.44646971,-0.111694615,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ranitidine,DB00863
,5132,DB01175,10018884,90,10634,49,4843,0.313595166,0.836522486,0.583229334,1.212251687,0.481072526,DB0117510018884_,0.731737238,-0.178501878,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,escitalopram,DB01175
,5133,DB01373,10018884,250,22470,73,7308,0.436094572,1.113808886,0.853737217,1.468288251,0.604686826,DB0137310018884_,0.503044597,0.10778557,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,calcium,DB01373
,5134,DB00635,10043554,231,32822,285,23509,8.87872103401591e-10,0.580564995,0.485536195,0.693581435,2.49334596558876e-08,DB0063510043554_,17.50705517,-0.54375352,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,5135,DB00863,10043554,56,10617,78,5762,8.29044345300639e-08,0.389663185,0.270960811,0.557236843,1.52601054735485e-06,DB0086310043554_,13.39285371,-0.942472542,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,ranitidine,DB00863
,5136,DB01175,10043554,58,10666,24,4868,0.722164259,1.102965708,0.673713376,1.85851888,0.836344262,DB0117510043554_,0.178714954,0.09800265,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,escitalopram,DB01175
,5137,DB01373,10043554,103,22617,54,7327,0.005159833,0.61793478,0.439862157,0.876587617,0.020975287,DB0137310043554_,3.86441036,-0.481372361,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,calcium,DB01373
,5138,DB00016,10047942,63,2699,39,2251,0.159885513,1.347170844,0.885779289,2.071717486,0.297307538,DB0001610047942_,1.212988196,0.298006722,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,erythropoietin,DB00016
,5139,DB00169,10047942,714,37977,258,17917,0.000232281,1.305681558,1.129519252,1.513027782,0.001632271,DB0016910047942_,6.417783262,0.266725171,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,5140,DB00480,10047942,2016,65412,1778,65884,5.83650525834554e-05,1.142037994,1.069986015,1.21906533,0.000504066,DB0048010047942_,7.592802997,0.13281438,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,5141,DB00635,10047942,236,32817,184,23610,0.427210005,0.922767273,0.757155607,1.125981273,0.595866112,DB0063510047942_,0.517739282,-0.080378218,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,prednisone,DB00635
,5142,DB00863,10047942,118,10555,85,5755,0.054786674,0.756955427,0.566786316,1.014446133,0.133978484,DB0086310047942_,2.01007606,-0.278450908,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,ranitidine,DB00863
,5143,DB01175,10047942,118,10606,49,4843,0.615450713,1.099626435,0.780288959,1.570202162,0.756846991,DB0117510047942_,0.278594172,0.094970518,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,escitalopram,DB01175
,5144,DB01373,10047942,457,22263,135,7246,0.359244752,1.101781211,0.905617579,1.347628664,0.529035144,DB0137310047942_,0.636700414,0.096928153,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,calcium,DB01373
,5146,DB00115,10013700,244,18181,66,10406,1.27445238548341e-08,2.115930172,1.604206339,2.824196151,2.79624214961865e-07,DB0011510013700_,15.08981922,0.749494513,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,cyanocobalamin,DB00115
,5148,DB00213,10013700,437,18458,135,13286,1.41152245519255e-19,2.329926425,1.914087733,2.850993239,1.40537377783092e-17,DB0021310013700_,38.80364328,0.84583669,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,pantoprazole,DB00213
,5149,DB00836,10013700,54,5481,16,4059,0.000911667,2.499139563,1.406656931,4.684681367,0.005107839,DB0083610013700_,5.276978842,0.915946498,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,loperamide,DB00836
,5150,DB01069,10013700,428,6272,78,2317,1.88597068098553e-09,2.026938237,1.58096349,2.62703802,4.9449116558309e-08,DB0106910013700_,16.82232164,0.706526397,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,promethazine,DB01069
,5151,DB01222,10013700,162,9112,45,5360,2.93939302782781e-06,2.11754729,1.510686484,3.021205924,3.71988183613163e-05,DB0122210013700_,10.19923356,0.75025848,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,budesonide,DB01222
,5152,DB01373,10013700,218,22502,43,7338,0.001852686,1.6531869,1.186215631,2.352131934,0.009137417,DB0137310013700_,4.695377533,0.50270488,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,calcium,DB01373
,5153,DB13961,10013700,148,9309,40,6374,3.1921407785077e-08,2.533290166,1.773048401,3.693868482,6.41724056314148e-07,DB1396110013700_,14.25910744,0.929518919,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,fish oil,DB13961
,5158,DB00316,10028034,69,65405,25,36928,0.067113048,1.558303391,0.973218738,2.571109165,0.156188096,DB0031610028034_,1.856694252,0.44359766,NA,10028034,Mouth ulceration,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,5166,DB00451,10015916,106,47165,18,15401,0.008707913,1.922808808,1.15938107,3.370043306,0.031887363,DB0045110015916_,3.445545479,0.653787038,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,levothyroxine,DB00451
,5177,DB01222,10003549,240,9034,143,5262,0.830178642,0.9775552,0.789143552,1.214507398,0.910907541,DB0122210003549_,0.093313879,-0.022700518,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,5178,DB01222,10044565,90,9184,42,5363,0.240137947,1.25133117,0.856897036,1.853472874,0.398009076,DB0122210044565_,0.921280471,0.224207921,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,5179,DB01222,10061428,137,9137,75,5330,0.719973274,1.065574128,0.796601341,1.434617273,0.834707899,DB0122210061428_,0.180673436,0.063513741,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,budesonide,DB01222
,5184,DB00811,10029354,47,2751,76,4080,0.710782013,0.917174563,0.621458359,1.341453463,0.827537715,DB0081110029354_,0.189300596,-0.086457462,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,ribavirin,DB00811
,5191,DB00193,10043607,133,19187,95,8607,0.000702415,0.628029716,0.478391912,0.827105042,0.004104254,DB0019310043607_,5.495731338,-0.465167795,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,tramadol,DB00193
,5192,DB00425,10043607,69,12626,51,7433,0.219265206,0.796505914,0.545943708,1.168701718,0.372612636,DB0042510043607_,0.987215909,-0.227520725,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,zolpidem,DB00425
,5193,DB00656,10043607,49,11964,38,6581,0.116648934,0.709338453,0.45437366,1.114869769,0.236100353,DB0065610043607_,1.443498342,-0.3434225,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,trazodone,DB00656
,5195,DB00425,10053762,355,12340,182,7302,0.123826095,1.154230093,0.960263221,1.391055095,0.246844557,DB0042510053762_,1.398996466,0.143433536,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,5196,DB00656,10053762,370,11643,180,6439,0.174873944,1.136810157,0.946184959,1.369748,0.317299666,DB0065610053762_,1.147908634,0.128226233,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,5197,DB08901,10053762,42,465,47,533,0.912284125,1.024280456,0.646394016,1.618770658,0.960594091,DB0890110053762_,0.040203341,0.023990372,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ponatinib,DB08901
,5198,DB00273,10027175,154,8327,26,2167,0.040648643,1.541333656,1.00947149,2.440973077,0.106938956,DB0027310027175_,2.235497112,0.432648052,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,5199,DB00776,10027175,34,1871,18,1321,0.394604303,1.333514436,0.728624795,2.519324582,0.564518143,DB0077610027175_,0.571782755,0.28781789,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,oxcarbazepine,DB00776
,5201,DB01015,10027175,59,9828,32,9349,0.011294867,1.753830322,1.120800609,2.790260812,0.039208345,DB0101510027175_,3.238865662,0.561802152,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,5203,DB08908,10027175,274,10399,73,3206,0.304883768,1.157162477,0.887932209,1.524075907,0.471681569,DB0890810027175_,0.751451164,0.145970868,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,5204,DB00331,10003983,33,24913,26,20726,0.896279885,1.055929509,0.612262631,1.838966701,0.956301489,DB0033110003983_,0.044682051,0.05442143,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,5209,DB01276,10028813,165,1852,99,1412,0.070488185,1.270612149,0.974504092,1.66332682,0.162183294,DB0127610028813_,1.819028138,0.239498791,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,exenatide,DB01276
,5210,DB01307,10028813,159,2365,73,1996,1.80550398251155e-05,1.838006883,1.375139569,2.475822863,0.000182494,DB0130710028813_,8.608790997,0.608681769,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,insulin detemir,DB01307
,5211,DB08907,10028813,181,4072,125,3785,0.012131334,1.345890573,1.060834459,1.711839048,0.041506294,DB0890710028813_,3.181910189,0.29705593,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,canagliflozin,DB08907
,5212,DB01276,10047895,81,1936,57,1454,0.726564822,1.067253384,0.745693851,1.536013184,0.840015674,DB0127610047895_,0.174334728,0.065088417,NA,10047895,Weight decreased,10022891,Investigations,Inv,exenatide,DB01276
,5213,DB01307,10047895,50,2474,35,2034,0.51002082,1.174459216,0.744182036,1.871754827,0.670563088,DB0130710047895_,0.39963749,0.1608078,NA,10047895,Weight decreased,10022891,Investigations,Inv,insulin detemir,DB01307
,5214,DB08907,10047895,148,4105,182,3728,0.008118304,0.738536293,0.587682131,0.926886385,0.030148294,DB0890710047895_,3.501626926,-0.303085034,NA,10047895,Weight decreased,10022891,Investigations,Inv,canagliflozin,DB08907
,5215,DB00331,10049803,57,24889,39,20713,0.35777598,1.216308256,0.794987547,1.878371568,0.5274928,DB0033110049803_,0.639620064,0.195820251,NA,10049803,Blood glucose fluctuation,10022891,Investigations,Inv,metformin,DB00331
,5220,DB00331,10061428,414,24532,355,20397,0.68791877,0.969618492,0.838360168,1.121889993,0.811850707,DB0033110061428_,0.208438814,-0.030852592,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,5221,DB01067,10061428,85,4276,96,4727,0.94011125,0.978803297,0.720063361,1.328598497,0.979472459,DB0106710061428_,0.020741159,-0.021424579,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,glipizide,DB01067
,5222,DB01276,10061428,40,1977,16,1495,0.029874106,1.890157849,1.030441107,3.630168232,0.084448122,DB0127610061428_,2.471617872,0.636660344,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,exenatide,DB01276
,5223,DB01307,10061428,57,2467,40,2029,0.471621424,1.171959728,0.765095175,1.810385429,0.637802389,DB0130710061428_,0.449726778,0.158677329,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,insulin detemir,DB01307
,5229,DB00537,10043255,49,7508,25,4273,0.716859115,1.115492949,0.67462148,1.887606321,0.832584753,DB0053710043255_,0.183220257,0.109296414,NA,10043255,Tendonitis,10028395,Musculoskeletal and connective tissue disorders,Musc,ciprofloxacin,DB00537
,5230,DB00381,10002034,532,28828,380,22507,0.200767106,1.093054667,0.955270463,1.251598016,0.349874918,DB0038110002034_,1.050179564,0.088976224,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,amlodipine,DB00381
,5231,DB00678,10002034,249,15350,178,10546,0.691463809,0.961054202,0.7884066,1.173541637,0.813971701,DB0067810002034_,0.205829679,-0.039724469,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,losartan,DB00678
,5232,DB00864,10002034,108,6761,135,8257,0.896638572,0.977014329,0.7498765,1.270486902,0.956301489,DB0086410002034_,0.044682051,-0.023253961,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,tacrolimus,DB00864
,5234,DB00016,10002965,24,2738,50,2240,0.000135007,0.392765028,0.2300668,0.653588087,0.001029645,DB0001610002965_,6.878541079,-0.934543739,NA,10002965,Aplasia pure red cell,10005329,Blood and lymphatic system disorders,Blood,erythropoietin,DB00016
,5245,DB01255,10061428,43,2090,78,1500,8.66763208492283e-07,0.395754844,0.264560575,0.585260453,1.26395955257807e-05,DB0125510061428_,11.27867617,-0.92696034,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,lisdexamfetamine,DB01255
,5246,DB06403,10035664,892,20579,256,6405,0.271925775,1.084471898,0.939954585,1.254636529,0.43477611,DB0640310035664_,0.83292407,0.081093138,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,5248,DB00005,10037162,958,127124,567,41852,1.36225092327386e-26,0.556263652,0.500556737,0.618601392,2.36348287249198e-24,DB0000510037162_,54.40190591,-0.586512902,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,5249,DB00005,10041232,308,127774,79,42340,0.045154032,1.291895695,1.005692878,1.676354149,0.115871692,DB0000510041232_,2.155271807,0.256110671,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,5250,DB00005,10043521,386,127696,98,42321,0.017775821,1.30537376,1.042986362,1.646935437,0.056341187,DB0000510043521_,2.87632944,0.266489406,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,5252,DB00005,10043224,169,127913,36,42383,0.015086825,1.555419738,1.080016906,2.295907154,0.049554163,DB0000510043224_,3.004689014,0.441745437,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,5254,DB00060,10016173,598,8910,132,2333,0.088980828,1.186197831,0.975135902,1.451344713,0.193566256,DB0006010016173_,1.642135419,0.170753092,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,interferon beta-1a,DB00060
,5255,DB05259,10022086,1001,10269,224,2504,0.273729232,1.089655977,0.935337395,1.273503286,0.436786939,DB0525910022086_,0.828309756,0.085862029,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,5256,DB05259,10022095,1163,10107,243,2485,0.027746448,1.176714745,1.016577374,1.366162768,0.079665029,DB0525910022095_,2.529924569,0.162726441,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,5257,DB05259,10028372,138,11132,43,2685,0.156064367,0.774088194,0.544529388,1.120038484,0.292248914,DB0525910028372_,1.230149394,-0.256069466,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,glatiramer,DB05259
,5259,DB00264,10003239,703,28904,370,24522,6.91419232877695e-14,1.611931194,1.417568993,1.835306281,3.62753583556691e-12,DB0026410003239_,26.34246753,0.47743296,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,5260,DB00451,10003239,1437,45834,300,15119,1.12222734408999e-13,1.579973848,1.392263025,1.797825433,5.68905414453334e-12,DB0045110003239_,25.89247711,0.457408295,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,5261,DB00678,10003239,444,15155,192,10532,3.10319881780283e-08,1.60704609,1.35114601,1.917125494,6.25518258634566e-07,DB0067810003239_,14.28468532,0.474397767,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,5262,DB00695,10003239,730,27319,320,20208,2.15488464296589e-15,1.687427757,1.475647073,1.93292594,1.38486901810167e-13,DB0069510003239_,29.60800065,0.523205332,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,5264,DB01275,10003239,88,3891,33,3316,3.05330945605549e-05,2.272287527,1.502694825,3.5107555,0.000288277,DB0127510003239_,8.151589703,0.820787045,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydralazine,DB01275
,5270,DB01275,10018364,38,3941,22,3327,0.192923045,1.458090542,0.838749904,2.593796769,0.340288702,DB0127510018364_,1.077960897,0.377127732,NA,10018364,Glomerulonephritis,10038359,Renal and urinary disorders,Renal,hydralazine,DB01275
,5276,DB01275,10047115,60,3919,34,3315,0.075958144,1.492644547,0.961486249,2.35141842,0.171423289,DB0127510047115_,1.763619409,0.400549411,NA,10047115,Vasculitis,10047065,Vascular disorders,Vasc,hydralazine,DB01275
,5277,DB00264,10047895,578,29029,541,24351,0.073598091,0.896223949,0.794679135,1.010846703,0.167520421,DB0026410047895_,1.786650018,-0.109564955,NA,10047895,Weight decreased,10022891,Investigations,Inv,metoprolol,DB00264
,5278,DB00678,10047895,307,15292,255,10469,0.026812533,0.824224035,0.69445942,0.97884136,0.077585151,DB0067810047895_,2.556379227,-0.193312898,NA,10047895,Weight decreased,10022891,Investigations,Inv,losartan,DB00678
,5279,DB00695,10047895,634,27415,513,20015,0.090281604,0.902278638,0.800703121,1.017127508,0.195699486,DB0069510047895_,1.631175033,-0.102831895,NA,10047895,Weight decreased,10022891,Investigations,Inv,furosemide,DB00695
,5281,DB01275,10047895,70,3909,69,3280,0.346181691,0.851270646,0.599587085,1.208877912,0.515589753,DB0127510047895_,0.662443882,-0.161025168,NA,10047895,Weight decreased,10022891,Investigations,Inv,hydralazine,DB01275
,5287,DB01275,10050551,51,3928,37,3312,0.51956538,1.162193037,0.744282192,1.830303526,0.678751984,DB0127510050551_,0.387499485,0.150308769,NA,10050551,Lupus-like syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,hydralazine,DB01275
,5291,DB01234,10047531,43,31582,28,32860,0.057298567,1.59783599,0.969870674,2.671632745,0.138383133,DB0123410047531_,1.977729115,0.468650208,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,dexamethasone,DB01234
,5297,DB00916,10013700,1220,4103,141,2290,4.76486557807728e-88,4.828327778,4.021298477,5.833284632,7.82778073248509e-85,DB0091610013700_,193.6620539,1.574500192,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,metronidazole,DB00916
,5304,DB00230,10042727,49,19625,14,8637,0.17169804,1.540345905,0.836327213,3.022822896,0.313017268,DB0023010042727_,1.16149692,0.432007005,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,5306,DB00316,10042727,111,65363,32,36921,0.000468308,1.959347426,1.311633507,3.002031543,0.002923866,DB0031610042727_,5.834848614,0.672611472,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,5309,DB00482,10000059,157,8102,53,3018,0.583678838,1.103434369,0.800943808,1.540904956,0.731616512,DB0048210000059_,0.312498792,0.09842747,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,celecoxib,DB00482
,5310,DB00482,10013700,1733,6526,356,2715,1.81985680101752e-32,2.025096202,1.789792049,2.295683424,4.68969960928876e-30,DB0048210013700_,67.53218426,0.705617207,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,celecoxib,DB00482
,5311,DB00482,10017885,66,8193,20,3051,0.466642962,1.228858457,0.734216745,2.144071317,0.633314071,DB0048210017885_,0.456788818,0.206085654,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,celecoxib,DB00482
,5312,DB00482,10047700,190,8069,57,3014,0.168910444,1.245056732,0.918594529,1.709989639,0.30939844,DB0048210047700_,1.173125384,0.219181097,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,celecoxib,DB00482
,5313,DB00480,10035742,37,67391,64,67598,0.009319459,0.579906622,0.375978031,0.882790641,0.033637072,DB0048010035742_,3.392126494,-0.544888185,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,5314,DB08908,10000081,164,10509,39,3240,0.15668987,1.29643813,0.907331658,1.893117768,0.293013179,DB0890810000081_,1.227537693,0.259620604,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,5315,DB08908,10000087,304,10369,57,3222,0.00032432,1.657130911,1.2415384,2.24594676,0.002150197,DB0890810000087_,6.142195595,0.50508774,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,5316,DB08908,10013968,147,10526,45,3234,1,1.003648033,0.712454457,1.43810401,1,DB0890810013968_,0,0.003641395,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dimethyl fumarate,DB08908
,5317,DB08908,10016256,444,10229,137,3142,0.960159541,0.99548685,0.816559851,1.219775768,0.997758151,DB0890810016256_,0.002244366,-0.004523365,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,5318,DB08908,10028813,605,10068,106,3173,7.12098414992339e-09,1.798775737,1.454987049,2.241186013,1.65203061236307e-07,DB0890810028813_,15.61609045,0.587106287,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,5319,DB08908,10047700,424,10249,85,3194,0.000152116,1.55443638,1.224350493,1.99285174,0.001140925,DB0890810047700_,6.775915628,0.441113023,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,5324,DB00654,10013700,106,3710,27,2571,6.79876374075193e-07,2.720239882,1.762883385,4.332099759,1.01855517199011e-05,DB0065410013700_,11.49454034,1.000720068,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,latanoprost,DB00654
,5329,DB00153,10002034,142,7281,79,3360,0.189016732,0.829518275,0.623619398,1.109982929,0.335311115,DB0015310002034_,1.092696476,-0.186910138,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ergocalciferol,DB00153
,5330,DB00268,10002034,38,2937,17,1528,0.669594277,1.162878206,0.638216248,2.204885158,0.799431576,DB0026810002034_,0.223854334,0.150898144,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ropinirole,DB00268
,5331,DB00641,10002034,242,13882,254,12221,0.056385514,0.838764803,0.699225215,1.005952042,0.136787562,DB0064110002034_,1.989326195,-0.175824942,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,simvastatin,DB00641
,5332,DB01041,10002034,44,3001,55,3063,0.361945853,0.816555928,0.534707673,1.240588023,0.531672447,DB0104110002034_,0.631727681,-0.202659871,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,thalidomide,DB01041
,5333,DB01136,10002034,232,9652,223,10892,0.096497147,1.174003375,0.970582025,1.420297622,0.205511871,DB0113610002034_,1.582251478,0.160419596,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,carvedilol,DB01136
,5335,DB08877,10002034,158,3131,202,3027,0.010781823,0.756232848,0.60643552,0.941712156,0.03780938,DB0887710002034_,3.275198051,-0.27940595,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ruxolitinib,DB08877
,5338,DB00213,10005364,61,18834,56,13365,0.188036768,0.772994319,0.528540565,1.132307788,0.334091283,DB0021310005364_,1.09634102,-0.257483579,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,pantoprazole,DB00213
,5340,DB00316,10005364,122,65352,111,36842,0.000360645,0.619587548,0.475024314,0.808911618,0.002351663,DB0031610005364_,6.052632451,-0.478701268,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,acetaminophen,DB00316
,5341,DB00437,10005364,22,6899,46,11500,0.451767519,0.797212847,0.456332307,1.353859593,0.619393853,DB0043710005364_,0.479013936,-0.226633575,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,allopurinol,DB00437
,5342,DB00480,10005364,21,67407,40,67622,0.020397979,0.526680058,0.29500245,0.914870767,0.062767604,DB0048010005364_,2.768316201,-0.641162016,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,lenalidomide,DB00480
,5344,DB00761,10005364,68,15239,43,8582,0.553422096,0.890586712,0.598518155,1.338068998,0.707011279,DB0076110005364_,0.346708661,-0.115874807,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,potassium chloride,DB00761
,5345,DB00996,10005364,45,38908,36,22389,0.165378695,0.719320245,0.453596526,1.148055525,0.304634291,DB0099610005364_,1.188643269,-0.329448617,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,gabapentin,DB00996
,5347,DB01075,10005364,44,19904,24,11073,1,1.019920525,0.606419306,1.754697451,1,DB0107510005364_,0,0.019724708,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,diphenhydramine,DB01075
,5355,DB00316,10005630,27,65447,33,36920,0.00292973,0.461549446,0.266944362,0.791711152,0.013249821,DB0031610005630_,4.32377123,-0.77316609,NA,10005630,Blood lactate dehydrogenase increased,10022891,Investigations,Inv,acetaminophen,DB00316
,5367,DB00153,10013971,40,7383,20,3419,0.781697004,0.926190327,0.527888241,1.674928684,0.881141829,DB0015310013971_,0.126536679,-0.076675529,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,5368,DB00213,10013971,126,18769,57,13364,0.004183566,1.573926543,1.141343908,2.193470847,0.017716295,DB0021310013971_,4.03327042,0.45357348,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,5370,DB00316,10013971,283,65191,136,36817,0.12637471,1.175165427,0.954102543,1.453303117,0.250624894,DB0031610013971_,1.383797904,0.161408926,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,5371,DB00437,10013971,58,6863,50,11496,0.000645656,1.943056244,1.306371861,2.898900261,0.003830509,DB0043710013971_,5.564757596,0.664262117,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,5372,DB00480,10013971,71,67357,81,67581,0.465359449,0.879459573,0.630214116,1.224913193,0.632175984,DB0048010013971_,0.458587468,-0.128447681,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,5373,DB00641,10013971,64,14060,54,12421,0.853507886,1.047035402,0.716837579,1.534223546,0.92855921,DB0064110013971_,0.074121131,0.045962744,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,5374,DB00761,10013971,197,15110,80,8545,0.013943332,1.392573334,1.067087004,1.831682333,0.046415969,DB0076110013971_,3.070111718,0.331153355,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,5376,DB01075,10013971,71,19877,45,11052,0.497924592,0.877283523,0.595047967,1.305365102,0.660040743,DB0107510013971_,0.415453714,-0.130925051,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,5377,DB01136,10013971,69,9815,75,11040,0.867141949,1.034834248,0.73437745,1.4562852,0.940220532,DB0113610013971_,0.061640823,0.034241267,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,5381,DB00153,10015090,42,7381,18,3421,0.889532256,1.081461282,0.60813597,1.998999068,0.954089642,DB0015310015090_,0.046997648,0.078313166,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,5382,DB00213,10015090,115,18780,81,13340,1,1.008493365,0.751664678,1.358446503,1,DB0021310015090_,0,0.008457499,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,5384,DB00437,10015090,75,6846,97,11449,0.097083691,1.293021777,0.942128309,1.768772982,0.206418185,DB0043710015090_,1.577851142,0.256981942,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,5385,DB00641,10015090,90,14034,71,12404,0.526452892,1.120357865,0.810885263,1.552994841,0.684278119,DB0064110015090_,0.379390838,0.113648156,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,5387,DB01136,10015090,77,9807,91,11024,0.756951858,0.951147291,0.692025336,1.304428927,0.864024953,DB0113610015090_,0.14615363,-0.050086348,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,5389,DB08877,10015090,46,3243,49,3180,0.756705931,0.920568239,0.600067191,1.410057182,0.863836772,DB0887710015090_,0.146371449,-0.082764149,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ruxolitinib,DB08877
,5393,DB00316,10024378,138,65336,119,36834,0.000874269,0.653747773,0.507740615,0.842927844,0.004932422,DB0031610024378_,5.31192515,-0.42503367,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,5395,DB00641,10024378,25,14099,30,12445,0.28050403,0.735585354,0.41457035,1.294656946,0.444361734,DB0064110024378_,0.811116333,-0.307088697,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,simvastatin,DB00641
,5396,DB00761,10024378,42,15265,35,8590,0.095798233,0.675311301,0.420551316,1.090371288,0.204478992,DB0076110024378_,1.587290037,-0.392581507,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,potassium chloride,DB00761
,5397,DB00996,10024378,48,38905,43,22382,0.038233022,0.642228149,0.416474784,0.993060401,0.102093257,DB0099610024378_,2.281868596,-0.442811667,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,gabapentin,DB00996
,5399,DB01075,10024378,37,19911,30,11067,0.12701892,0.68555402,0.411838437,1.149654898,0.251469855,DB0107510024378_,1.380432158,-0.377527979,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,diphenhydramine,DB01075
,5403,DB00016,10035528,61,2701,60,2230,0.356225609,0.839412104,0.575295768,1.225151718,0.525910489,DB0001610035528_,0.642624253,-0.175053508,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,erythropoietin,DB00016
,5404,DB00153,10035528,73,7350,59,3380,0.00178074,0.569007227,0.397158862,0.818107228,0.00884147,DB0015310035528_,4.728302181,-0.563862144,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,ergocalciferol,DB00153
,5406,DB00437,10035528,168,6753,256,11290,0.361229462,1.097143846,0.895531391,1.341350778,0.531124707,DB0043710035528_,0.632758431,0.092710299,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,allopurinol,DB00437
,5407,DB00480,10035528,1436,65992,1696,65966,4.34037674900491e-06,0.846366599,0.787681499,0.909299262,5.2153967016043e-05,DB0048010035528_,9.86131031,-0.166802682,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,5408,DB00641,10035528,139,13985,135,12340,0.429813577,0.908522115,0.710812056,1.16151638,0.598297404,DB0064110035528_,0.513667318,-0.095936049,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,simvastatin,DB00641
,5409,DB00761,10035528,215,15092,135,8490,0.340401891,0.895919492,0.717838733,1.12140547,0.509624679,DB0076110035528_,0.674080747,-0.109904723,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,5410,DB00996,10035528,317,38636,241,22184,0.001246823,0.75527107,0.636211956,0.897468377,0.006598096,DB0099610035528_,5.020974169,-0.280678561,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,gabapentin,DB00996
,5411,DB01041,10035528,45,3000,41,3077,0.589441501,1.125709436,0.718461449,1.768195478,0.736206692,DB0104110035528_,0.306244368,0.118413447,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,thalidomide,DB01041
,5412,DB01075,10035528,150,19798,97,11000,0.257271975,0.859203971,0.660378304,1.122176907,0.418141528,DB0107510035528_,0.87193532,-0.151748934,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,diphenhydramine,DB01075
,5413,DB01136,10035528,105,9779,125,10990,0.690536323,0.944009528,0.720179608,1.235458953,0.813314839,DB0113610035528_,0.206636989,-0.05761902,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,carvedilol,DB01136
,5415,DB08877,10035528,156,3133,179,3050,0.145110709,0.848442811,0.676057507,1.063921694,0.277207475,DB0887710035528_,1.282989047,-0.164352597,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,ruxolitinib,DB08877
,5420,DB00316,10041660,41,65433,48,36905,0.000813729,0.481754013,0.309602548,0.746633382,0.004644198,DB0031610041660_,5.372136592,-0.730321641,NA,10041660,Splenomegaly,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,5421,DB00437,10041660,14,6907,37,11509,0.149644652,0.630499594,0.314624855,1.195119997,0.283488985,DB0043710041660_,1.26058201,-0.461242767,NA,10041660,Splenomegaly,10005329,Blood and lymphatic system disorders,Blood,allopurinol,DB00437
,5430,DB08877,10041660,58,3231,82,3147,0.032647917,0.6889712,0.481706128,0.9799491,0.090522205,DB0887710041660_,2.402160095,-0.372555808,NA,10041660,Splenomegaly,10005329,Blood and lymphatic system disorders,Blood,ruxolitinib,DB08877
,5431,DB00016,10050584,41,2721,11,2279,0.000375523,3.121066744,1.571075323,6.749392752,0.002433583,DB0001610050584_,6.01839045,1.138174849,female,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,erythropoietin,DB00016
,5432,DB00153,10050584,101,7322,30,3409,0.029788691,1.567404001,1.03144555,2.446465905,0.084242912,DB0015310050584_,2.474050847,0.449420748,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,ergocalciferol,DB00153
,5433,DB00213,10050584,184,18711,64,13357,2.6075796699013e-07,2.052286235,1.53489114,2.77446565,4.31070639140601e-06,DB0021310050584_,12.35440877,0.718954408,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,5435,DB00316,10050584,541,64933,195,36758,3.25973430883683e-08,1.570533124,1.330235614,1.860526536,6.53812409826602e-07,DB0031610050584_,14.24044536,0.451415131,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,5436,DB00437,10050584,72,6849,72,11474,0.002383548,1.675158877,1.189706901,2.358804104,0.011225867,DB0043710050584_,4.48953458,0.515908013,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,allopurinol,DB00437
,5437,DB00480,10050584,337,67091,203,67459,6.34969827173866e-09,1.669187468,1.397852775,1.997332971,1.49219328629996e-07,DB0048010050584_,15.71784861,0.512336962,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,5438,DB00641,10050584,133,13991,64,12411,4.08939822344808e-05,1.843395598,1.356735397,2.5269955,0.000371808,DB0064110050584_,7.897131668,0.611609305,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,5439,DB00761,10050584,161,15146,53,8572,0.000441951,1.719194177,1.251683467,2.394187885,0.002786441,DB0076110050584_,5.882990044,0.54185568,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,5440,DB00996,10050584,331,38622,90,22335,1.92797617909576e-11,2.126822362,1.678943173,2.717343861,7.0140974211117e-10,DB0099610050584_,21.07792889,0.754629017,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,5442,DB01075,10050584,157,19791,52,11045,0.000838266,1.684951353,1.223015758,2.354331683,0.00475841,DB0107510050584_,5.347841607,0.521736693,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,5443,DB01136,10050584,81,9803,62,11053,0.023118368,1.473000228,1.043910367,2.087232811,0.069190834,DB0113610050584_,2.670886884,0.387301292,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,5445,DB00193,10000081,300,19020,114,8588,0.121057162,1.188201846,0.953092342,1.489711443,0.242955449,DB0019310000081_,1.414877191,0.17244111,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,5446,DB00338,10000081,642,33032,349,21923,0.002876293,1.220863506,1.06876107,1.396475777,0.013063214,DB0033810000081_,4.337955114,0.1995584,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,5447,DB00425,10000081,226,12469,104,7380,0.03843656,1.28615876,1.013262057,1.641519525,0.102517517,DB0042510000081_,2.277721602,0.25166007,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,5448,DB00476,10000081,245,17012,58,6119,0.003801765,1.519281414,1.135188492,2.062611527,0.016369792,DB0047610000081_,4.11231758,0.418237469,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,5449,DB00586,10000081,84,7025,31,2774,0.835154143,1.069977307,0.69922373,1.675845017,0.914685493,DB0058610000081_,0.089174996,0.06763744,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,diclofenac,DB00586
,5451,DB01238,10000081,58,5192,16,3486,0.001146198,2.433656755,1.377492073,4.543280417,0.006168043,DB0123810000081_,5.088373614,0.889394964,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,aripiprazole,DB01238
,5452,DB01611,10000081,128,11785,15,2346,0.053843853,1.698640027,0.989926434,3.129547809,0.13222026,DB0161110000081_,2.023286107,0.529827947,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,5453,DB06643,10000081,165,52256,31,7484,0.160797631,0.762294527,0.51655618,1.158891642,0.298602263,DB0664310000081_,1.208642816,-0.27142228,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,5456,DB00338,10002424,50,33624,64,22208,0.000511151,0.515996149,0.34900903,0.759148639,0.003143564,DB0033810002424_,5.762398172,-0.661655977,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,5464,DB00186,10003239,382,16519,133,9875,3.76189563672253e-08,1.716945615,1.403487659,2.111007713,7.45150164365123e-07,DB0018610003239_,14.10968008,0.540546907,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,5465,DB00193,10003239,579,18741,181,8521,8.27897096901465e-06,1.454428492,1.226214288,1.731757866,9.21697382128547e-05,DB0019310003239_,9.2918787,0.374613035,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,5466,DB00338,10003239,962,32712,382,21890,1.57676422452516e-18,1.685177264,1.493311386,1.904547635,1.4193577959467e-16,DB0033810003239_,36.49115697,0.521870759,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,5467,DB00425,10003239,317,12378,143,7341,0.00719277,1.314686668,1.073395555,1.616627097,0.027362612,DB0042510003239_,3.598577728,0.273598362,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,5468,DB00476,10003239,523,16734,122,6055,8.46480194652114e-06,1.551195029,1.268370237,1.909106148,9.39005356253674e-05,DB0047610003239_,9.273274468,0.43902562,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,5469,DB00586,10003239,297,6812,72,2733,9.63194501704809e-05,1.654890196,1.269975685,2.180275606,0.000771524,DB0058610003239_,7.167142485,0.50373466,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,5470,DB00783,10003239,373,16341,6,367,0.591083601,1.396173281,0.629314125,3.854259309,0.737527093,DB0078310003239_,0.304452455,0.333735123,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,estradiol,DB00783
,5471,DB01238,10003239,76,5174,23,3479,0.000590442,2.22165177,1.374766763,3.720078767,0.003548188,DB0123810003239_,5.64131816,0.79825096,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,aripiprazole,DB01238
,5472,DB01611,10003239,533,11380,79,2282,0.012313147,1.352893478,1.061488046,1.743591932,0.042010783,DB0161110003239_,3.16982896,0.302245616,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,5473,DB06643,10003239,1967,50454,153,7362,8.30920438560745e-16,1.875892733,1.587571922,2.230160028,5.60737964764292e-14,DB0664310003239_,30.51210778,0.62908467,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,5474,DB00186,10003988,361,16540,158,9850,0.001306858,1.360648704,1.123566203,1.653853245,0.006859861,DB0018610003988_,4.982068099,0.307961574,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,5475,DB00193,10003988,436,18884,168,8534,0.083104751,1.172813831,0.977486429,1.412411565,0.183617735,DB0019310003988_,1.694899208,0.159405845,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,5476,DB00338,10003988,779,32895,414,21858,0.000262471,1.250299441,1.106964596,1.413755334,0.001807924,DB0033810003988_,6.315576108,0.223383075,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,5477,DB00476,10003988,389,16868,106,6071,0.011455023,1.320771074,1.060675587,1.656541494,0.0396939,DB0047610003988_,3.226557756,0.278215713,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,5478,DB00586,10003988,166,6943,45,2760,0.02480637,1.466416062,1.045741459,2.093032124,0.073061286,DB0058610003988_,2.61645666,0.382821371,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,5480,DB01238,10003988,58,5192,26,3476,0.093903979,1.493414793,0.923174347,2.476797528,0.20159808,DB0123810003988_,1.601479267,0.401065305,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,aripiprazole,DB01238
,5481,DB01611,10003988,209,11704,27,2334,0.033689789,1.543603422,1.027978153,2.404334029,0.092750574,DB0161110003988_,2.377841384,0.434119568,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,5482,DB00186,10005191,34,16867,21,9987,0.889523281,0.958667236,0.540254388,1.739156559,0.954089642,DB0018610005191_,0.046997648,-0.042211255,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,5483,DB00193,10005191,69,19251,22,8680,0.173767593,1.414162056,0.863575728,2.402122606,0.315860154,DB0019310005191_,1.152455714,0.346537169,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,5484,DB00338,10005191,130,33544,67,22205,0.108503295,1.284403994,0.94881084,1.752354675,0.223786475,DB0033810005191_,1.497062919,0.250294793,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,5485,DB00425,10005191,40,12655,12,7472,0.0432362,1.968066607,1.011449988,4.123577388,0.112141087,DB0042510005191_,2.187997496,0.677051643,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,zolpidem,DB00425
,5486,DB00476,10005191,56,17201,14,6163,0.276926084,1.43311394,0.786669183,2.790078888,0.440404292,DB0047610005191_,0.82006213,0.359849657,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,duloxetine,DB00476
,5490,DB01611,10005191,45,11868,7,2354,0.708369645,1.275076247,0.56986193,3.355477554,0.825838018,DB0161110005191_,0.191356629,0.243005978,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxychloroquine,DB01611
,5491,DB06643,10005191,86,52335,9,7506,0.439537114,1.370471692,0.688901614,3.099886859,0.607910896,DB0664310005191_,0.497726961,0.315154981,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,5502,DB00186,10008479,222,16679,114,9894,0.232947617,1.155204683,0.916226069,1.462968387,0.389480829,DB0018610008479_,0.942940634,0.144277543,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,5503,DB00193,10008479,261,19059,111,8591,0.651895643,1.059888069,0.844306509,1.337717193,0.78617341,DB0019310008479_,0.240577888,0.058163308,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,5504,DB00476,10008479,218,17039,73,6104,0.687906153,1.069800163,0.815729333,1.416697843,0.811850707,DB0047610008479_,0.208438814,0.067471868,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,5505,DB00586,10008479,88,7021,27,2778,0.297490576,1.289535508,0.827501033,2.070048419,0.463407598,DB0058610008479_,0.769148272,0.254282082,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,5507,DB01238,10008479,56,5194,18,3484,0.005825978,2.086684727,1.206041893,3.778676446,0.023125316,DB0123810008479_,3.766827351,0.735576551,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,5508,DB01611,10008479,138,11775,22,2339,0.392117532,1.246003029,0.788806428,2.057575903,0.561985241,DB0161110008479_,0.576279691,0.219940852,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,5509,DB06643,10008479,163,52258,29,7486,0.275166974,0.80517192,0.539516823,1.241122038,0.43846891,DB0664310008479_,0.824466371,-0.21669946,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,5510,DB00186,10011469,62,16839,12,9996,9.64897194140662e-05,3.066930493,1.635786301,6.256257392,0.000772653,DB0018610011469_,7.165680983,1.120677222,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,5512,DB00338,10011469,74,33600,12,22260,2.12421499664413e-07,4.085320014,2.20398606,8.262101537,3.58146191063445e-06,DB0033810011469_,12.53973949,1.407400064,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,5514,DB00476,10011469,158,17099,21,6156,2.1554229244734e-06,2.708837331,1.710366466,4.50208086,2.83064159729119e-05,DB0047610011469_,10.47242207,0.996519514,NA,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,5517,DB01238,10011469,44,5206,14,3488,0.014885524,2.105531536,1.130440736,4.166298678,0.0490124,DB0123810011469_,3.015681946,0.744567947,NA,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,5520,DB00186,10012735,1039,15862,444,9564,1.87714466329694e-09,1.410940235,1.257595061,1.584955179,4.92422629488623e-08,DB0018610012735_,16.82651358,0.344256315,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,5521,DB00425,10012735,695,12000,322,7162,0.00021585,1.288169519,1.123354264,1.479570721,0.00153632,DB0042510012735_,6.478365551,0.253222233,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,5522,DB00476,10012735,1368,15889,456,5721,0.175150006,1.080176646,0.966576479,1.20875041,0.317668995,DB0047610012735_,1.146745335,0.077124588,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,5523,DB00586,10012735,349,6760,128,2677,0.498331099,1.079725521,0.874716052,1.339358665,0.660264011,DB0058610012735_,0.415115508,0.076706862,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,diclofenac,DB00586
,5524,DB00783,10012735,551,16163,11,362,0.882851696,1.121871944,0.614675634,2.281125582,0.951043643,DB0078310012735_,0.050195326,0.114998669,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,estradiol,DB00783
,5525,DB01238,10012735,125,5125,67,3435,0.15705047,1.250420953,0.918939567,1.714170182,0.293551758,DB0123810012735_,1.225701308,0.223480257,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,aripiprazole,DB01238
,5526,DB01611,10012735,487,11426,57,2304,5.91380130815414e-05,1.7227572,1.302097227,2.317172719,0.000509737,DB0161110012735_,7.581615849,0.543926031,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,5527,DB06643,10012735,570,51851,154,7361,3.79552404429117e-11,0.525489267,0.438250906,0.633065128,1.3266668817047e-09,DB0664310012735_,20.44059614,-0.643425513,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,5528,DB00193,10013700,1484,17836,273,8429,2.16103023820607e-53,2.568840519,2.250129083,2.941095984,1.438042526867e-50,DB0019310013700_,114.7659718,0.943454637,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,tramadol,DB00193
,5529,DB00425,10013700,326,12369,100,7384,1.7045340037649e-09,1.946081099,1.547792918,2.464567259,4.5166550021952e-08,DB0042510013700_,16.91290907,0.665817658,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,zolpidem,DB00425
,5530,DB00476,10013700,939,16318,187,5990,1.97747447729155e-15,1.843206655,1.569199311,2.174223965,1.27866953593133e-13,DB0047610013700_,29.6877861,0.611506802,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,duloxetine,DB00476
,5531,DB00586,10013700,594,6515,124,2681,1.30079002154326e-12,1.971156882,1.612764725,2.424592193,5.76581209380514e-11,DB0058610013700_,23.57649001,0.67862062,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,diclofenac,DB00586
,5533,DB01238,10013700,115,5135,35,3467,1.58610109806414e-05,2.218222739,1.503558143,3.346590954,0.000162543,DB0123810013700_,8.724566844,0.796706307,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,aripiprazole,DB01238
,5534,DB01611,10013700,767,11146,58,2303,1.13004892022542e-16,2.732295382,2.081837442,3.646545694,8.40264098108208e-15,DB0161110013700_,32.41023034,1.005142055,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,hydroxychloroquine,DB01611
,5535,DB06643,10013700,190,52231,15,7500,0.020088564,1.818826408,1.07449825,3.315918873,0.061973728,DB0664310013700_,2.781044721,0.598191462,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,denosumab,DB06643
,5536,DB00193,10013968,754,18566,268,8434,0.000644282,1.278005913,1.107535574,1.478287083,0.00382381,DB0019310013968_,5.566507922,0.245300983,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,5537,DB00476,10013968,537,16720,167,6010,0.108238343,1.155824162,0.967229179,1.386938414,0.223412371,DB0047610013968_,1.498736017,0.144813649,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,5538,DB00586,10013968,230,6879,67,2738,0.026094909,1.366255674,1.032559885,1.82819662,0.075937414,DB0058610013968_,2.577845772,0.312073913,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diclofenac,DB00586
,5539,DB00783,10013968,427,16287,11,362,0.616970969,0.862794041,0.471682561,1.757278466,0.758073246,DB0078310013968_,0.276975268,-0.147579271,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,estradiol,DB00783
,5540,DB01238,10013968,106,5144,57,3445,0.197088944,1.245393207,0.891506668,1.755290431,0.34551525,DB0123810013968_,1.062718499,0.219451309,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,aripiprazole,DB01238
,5541,DB01611,10013968,400,11513,70,2291,0.344332055,1.137089457,0.876371628,1.493618703,0.513679052,DB0161110013968_,0.666156621,0.12847189,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxychloroquine,DB01611
,5542,DB06643,10013968,491,51930,120,7395,5.61079099041331e-07,0.582674524,0.475556444,0.718544111,8.60190383103026e-06,DB0664310013968_,11.663527,-0.540126527,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,denosumab,DB06643
,5553,DB00186,10015150,143,16758,46,9962,0.000199068,1.847961805,1.315793759,2.638192945,0.001434351,DB0018610015150_,6.547043063,0.614083305,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,5554,DB00193,10015150,137,19183,45,8657,0.064863372,1.373942808,0.973515874,1.971375193,0.152219432,DB0019310015150_,1.88243217,0.317684568,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,5555,DB00338,10015150,253,33421,127,22145,0.0115139,1.319990338,1.061693491,1.647910655,0.039860765,DB0033810015150_,3.222362784,0.277624417,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,5556,DB00425,10015150,93,12602,23,7461,6.76091270484728e-05,2.393842021,1.502002423,3.964532165,0.000569951,DB0042510015150_,7.469960905,0.872899615,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,zolpidem,DB00425
,5557,DB00476,10015150,117,17140,27,6150,0.036956392,1.554750529,1.014984885,2.461227065,0.099492592,DB0047610015150_,2.30767209,0.441315101,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,duloxetine,DB00476
,5558,DB00586,10015150,61,7048,24,2781,1,1.002890794,0.614669899,1.685533897,1,DB0058610015150_,0,0.002886624,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,diclofenac,DB00586
,5561,DB01611,10015150,94,11819,16,2345,0.69881274,1.165642585,0.680152881,2.126592534,0.81897108,DB0161110015150_,0.199706507,0.15327251,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxychloroquine,DB01611
,5562,DB06643,10015150,235,52186,23,7492,0.089123492,1.466834446,0.953544141,2.361223651,0.193828479,DB0664310015150_,1.640781639,0.383106641,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,5573,DB00186,10018867,33,16868,27,9981,0.22936364,0.723233593,0.421423282,1.251207402,0.3851362,DB0018610018867_,0.954158241,-0.324023021,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,lorazepam,DB00186
,5575,DB00338,10018867,62,33612,100,22172,1.89017039345445e-08,0.408984287,0.292859456,0.567290007,3.97465030335601e-07,DB0033810018867_,14.73815888,-0.894078542,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,5585,DB00338,10018870,35,33639,31,22241,0.25794515,0.746495585,0.446951071,1.252222471,0.418853168,DB0033810018870_,0.870234856,-0.292365577,NA,10018870,Blood urine present,10022891,Investigations,Inv,omeprazole,DB00338
,5593,DB00186,10020751,129,16772,55,9953,0.046286074,1.391845436,1.00653255,1.946847786,0.118061112,DB0018610020751_,2.136552894,0.330630519,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,lorazepam,DB00186
,5594,DB00193,10020751,254,19066,52,8650,2.43097928111387e-08,2.21603404,1.636945824,3.05043971,5.00966604500809e-07,DB0019310020751_,14.5067264,0.79571913,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,tramadol,DB00193
,5595,DB00338,10020751,330,33344,120,22152,5.35794503093665e-09,1.826932085,1.476991212,2.272380158,1.27856182603876e-07,DB0033810020751_,15.87235978,0.602638104,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,omeprazole,DB00338
,5596,DB00425,10020751,102,12593,32,7452,0.001201827,1.886170372,1.255522415,2.903735549,0.006413467,DB0042510020751_,5.049355319,0.634548515,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,zolpidem,DB00425
,5597,DB00476,10020751,150,17107,29,6148,0.001550405,1.858913749,1.241156762,2.873614776,0.007902239,DB0047610020751_,4.840609179,0.619992311,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,duloxetine,DB00476
,5598,DB00586,10020751,97,7012,19,2786,0.003521147,2.028295537,1.228697684,3.520802054,0.015396049,DB0058610020751_,4.173644353,0.707195804,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,diclofenac,DB00586
,5600,DB01238,10020751,47,5203,18,3484,0.042546018,1.74832815,0.994456372,3.204287755,0.110801753,DB0123810020751_,2.200012685,0.558659988,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,aripiprazole,DB01238
,5601,DB01611,10020751,154,11759,18,2343,0.029872541,1.704645684,1.040806546,2.958864874,0.084448122,DB0161110020751_,2.471617872,0.533357279,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,hydroxychloroquine,DB01611
,5602,DB06643,10020751,219,52202,17,7498,0.010326192,1.85033076,1.128543946,3.236479832,0.03651116,DB0664310020751_,3.310137313,0.615364412,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,denosumab,DB06643
,5603,DB00186,10023232,98,16803,33,9975,0.004768214,1.762906966,1.176319214,2.703251482,0.019692436,DB0018610023232_,3.927520673,0.566964132,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,5604,DB00193,10023232,171,19149,59,8643,0.085651551,1.308107747,0.966600536,1.79188025,0.187761229,DB0019310023232_,1.67258418,0.268581625,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,5605,DB00338,10023232,312,33362,121,22151,2.63010017695812e-07,1.712007714,1.382514898,2.131237637,4.34133759410293e-06,DB0033810023232_,12.34732806,0.537666784,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,5606,DB00425,10023232,85,12610,32,7452,0.034231431,1.569702801,1.033000579,2.439019942,0.093873048,DB0042510023232_,2.365811966,0.450886303,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,5607,DB00476,10023232,122,17135,26,6151,0.014677951,1.684454604,1.094727206,2.683719947,0.048465541,DB0047610023232_,3.026902224,0.521441834,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,5608,DB00586,10023232,94,7015,34,2771,0.694145102,1.092077605,0.728557888,1.672095725,0.815847075,DB0058610023232_,0.203528349,0.088081942,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,5611,DB01611,10023232,205,11708,40,2321,1,1.01598286,0.71878006,1.468186672,1,DB0161110023232_,0,0.015856479,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,5612,DB06643,10023232,167,52254,20,7495,0.507527306,1.197642622,0.750561634,2.012712895,0.668168762,DB0664310023232_,0.403214499,0.180355143,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,5623,DB00186,10030095,76,16825,48,9960,0.710830669,0.93729858,0.644026248,1.376009656,0.827557708,DB0018610030095_,0.189276437,-0.064753392,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,5624,DB00193,10030095,109,19211,26,8676,0.002707336,1.893276491,1.224175008,3.029015966,0.012432273,DB0019310030095_,4.387459528,0.638308921,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,5625,DB00338,10030095,235,33439,128,22144,0.076145718,1.215769232,0.975460698,1.521013581,0.171720663,DB0033810030095_,1.761886173,0.195376989,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,5626,DB00425,10030095,92,12603,37,7447,0.05443222,1.469215757,0.99184822,2.216603297,0.133316335,DB0042510030095_,2.015030514,0.38472876,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,5627,DB00476,10030095,73,17184,25,6152,0.908917394,1.045349529,0.655070044,1.720468808,0.95913476,DB0047610030095_,0.041723693,0.044351307,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,5631,DB01611,10030095,72,11841,8,2353,0.131198279,1.78837739,0.859152236,4.305752344,0.257531103,DB0161110030095_,1.356614779,0.581308723,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,5632,DB06643,10030095,39,52382,15,7500,0.002796305,0.372273903,0.200529996,0.727282885,0.012759324,DB0664310030095_,4.361492997,-0.988125397,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,5633,DB00186,10037087,296,16605,95,9913,4.84858980089938e-08,1.860049787,1.46934774,2.372442687,9.40902051802438e-07,DB0018610037087_,13.87642679,0.620603254,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,5634,DB00193,10037087,390,18930,120,8582,0.00016156,1.473384764,1.195760397,1.826323838,0.001201815,DB0019310037087_,6.723922325,0.387562314,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,5635,DB00338,10037087,700,32974,301,21971,1.20460121631971e-10,1.549551467,1.350292593,1.78163609,3.86604920280385e-09,DB0033810037087_,19.37103273,0.437965513,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,5636,DB00425,10037087,219,12476,67,7417,9.36675544719395e-07,1.943160231,1.469278884,2.598778978,1.35240410288104e-05,DB0042510037087_,11.21104164,0.664315633,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,zolpidem,DB00425
,5637,DB00476,10037087,317,16940,62,6115,4.05529032550514e-06,1.845664855,1.399609068,2.46788113,4.9155317595528e-05,DB0047610037087_,9.920525526,0.612839567,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,duloxetine,DB00476
,5638,DB00586,10037087,152,6957,51,2754,0.344925416,1.179791704,0.851018769,1.658916432,0.514345298,DB0058610037087_,0.664860454,0.165337901,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,diclofenac,DB00586
,5640,DB01238,10037087,50,5200,20,3482,0.05069514,1.673943326,0.976746207,2.974117394,0.126287425,DB0123810037087_,2.069194822,0.515182116,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,aripiprazole,DB01238
,5641,DB01611,10037087,233,11680,29,2332,0.014764919,1.604091163,1.084453887,2.454839163,0.048703758,DB0161110037087_,3.021999082,0.472557342,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxychloroquine,DB01611
,5642,DB06643,10037087,557,51864,40,7475,3.85086897525496e-06,2.006946056,1.453613654,2.842795606,4.69698798211492e-05,DB0664310037087_,9.966004017,0.696614191,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,5643,DB00186,10037844,477,16424,217,9791,0.001089544,1.310378802,1.111524693,1.548788759,0.005911324,DB0018610037844_,5.130885452,0.270316257,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,5644,DB00193,10037844,506,18814,181,8521,0.006643465,1.266092199,1.064175871,1.511773249,0.025702602,DB0019310037844_,3.661163064,0.235935148,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,5645,DB00338,10037844,897,32777,549,21723,0.14924316,1.082869673,0.971275371,1.208084661,0.282952716,DB0033810037844_,1.262475478,0.079614622,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,5646,DB00425,10037844,297,12398,151,7333,0.138055248,1.163372767,0.951053997,1.427746572,0.267024508,DB0042510037844_,1.320414833,0.151323344,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,zolpidem,DB00425
,5647,DB00476,10037844,426,16831,112,6065,0.002941008,1.37055383,1.108130764,1.70676729,0.013291678,DB0047610037844_,4.320617137,0.315214913,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,duloxetine,DB00476
,5648,DB00586,10037844,277,6832,101,2704,0.522040955,1.085458402,0.857297186,1.383218532,0.68074845,DB0058610037844_,0.384562425,0.082002389,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,diclofenac,DB00586
,5650,DB01238,10037844,77,5173,48,3454,0.782812192,1.071101277,0.735344474,1.573819935,0.881806742,DB0123810037844_,0.12578236,0.06868735,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,aripiprazole,DB01238
,5651,DB01611,10037844,455,11458,66,2295,0.016098508,1.380800421,1.060141026,1.822904089,0.052073503,DB0161110037844_,2.955099038,0.322663346,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxychloroquine,DB01611
,5652,DB06643,10037844,882,51539,86,7429,0.000347781,1.478296819,1.181917569,1.869435656,0.002281932,DB0664310037844_,6.082732648,0.390890627,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,5653,DB00186,10040829,52,16849,19,9989,0.084441344,1.622520171,0.942613812,2.907909358,0.185791908,DB0018610040829_,1.683128006,0.483980601,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,5654,DB00193,10040829,51,19269,21,8681,0.799448971,1.094105781,0.646064441,1.916229613,0.891654641,DB0019310040829_,0.114676396,0.089937392,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,5655,DB00338,10040829,150,33524,55,22217,0.000107365,1.807393923,1.31799468,2.509990565,0.000847853,DB0033810040829_,7.072803769,0.591885986,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,5656,DB00425,10040829,43,12652,22,7462,0.699867289,1.152787117,0.673896627,2.025226498,0.819622255,DB0042510040829_,0.19891171,0.14218259,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,zolpidem,DB00425
,5657,DB00476,10040829,45,17212,16,6161,1,1.006729135,0.557744334,1.909511626,1,DB0047610040829_,0,0.006706595,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,duloxetine,DB00476
,5662,DB06643,10040829,85,52336,14,7501,0.647489298,0.8701967,0.490923489,1.659880561,0.78269246,DB0664310040829_,0.245015432,-0.139036001,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,5673,DB00186,10042674,92,16809,35,9973,0.026865737,1.559541037,1.045182123,2.374359956,0.07771594,DB0018610042674_,2.554694896,0.444391571,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,5674,DB00193,10042674,180,19140,39,8663,9.64558625110469e-06,2.088932818,1.469283358,3.037090896,0.000105354,DB0019310042674_,9.158185106,0.736653322,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,5675,DB00425,10042674,74,12621,34,7450,0.27175781,1.284731086,0.844092248,1.991250536,0.434617385,DB0042510042674_,0.833289209,0.250549425,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,5676,DB00476,10042674,140,17117,23,6154,0.00022787,2.188426388,1.39977648,3.568781699,0.001607718,DB0047610042674_,6.432939249,0.783182741,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,5677,DB00586,10042674,71,7038,21,2784,0.294995609,1.337321596,0.810305276,2.296544496,0.46087621,DB0058610042674_,0.774625798,0.290668805,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,5679,DB01611,10042674,127,11786,10,2351,0.002421856,2.533214492,1.330518346,5.418757505,0.011371646,DB0161110042674_,4.476632197,0.929489046,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,5680,DB06643,10042674,122,52299,16,7499,0.897379687,1.093340075,0.646427547,1.974359785,0.956338178,DB0664310042674_,0.044643686,0.0892373,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,5681,DB00186,10043071,187,16714,116,9892,0.719937084,0.954101771,0.751725469,1.215092574,0.834684351,DB0018610043071_,0.180701649,-0.046984935,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,lorazepam,DB00186
,5682,DB00193,10043071,93,19227,50,8652,0.319405582,0.837007347,0.586744326,1.206366145,0.487590424,DB0019310043071_,0.718279521,-0.17792243,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,tramadol,DB00193
,5683,DB00338,10043071,177,33497,86,22186,0.019357179,1.363155356,1.047124535,1.785937264,0.060249076,DB0033810043071_,2.809268045,0.309802127,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,omeprazole,DB00338
,5684,DB00425,10043071,75,12620,38,7446,0.494665957,1.164527426,0.777237738,1.770668774,0.657155228,DB0042510043071_,0.419835021,0.152315362,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,zolpidem,DB00425
,5685,DB00476,10043071,98,17159,29,6148,0.419332606,1.210776311,0.792059667,1.903103872,0.588376655,DB0047610043071_,0.530387967,0.191261733,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,duloxetine,DB00476
,5689,DB01611,10043071,57,11856,16,2345,0.208013874,0.704647915,0.398264309,1.317024157,0.358831051,DB0161110043071_,1.02490361,-0.350057012,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,hydroxychloroquine,DB01611
,5701,DB00186,10046735,140,16761,52,9956,0.003406764,1.599198352,1.154247439,2.245405588,0.014994437,DB0018610046735_,4.20007599,0.469502474,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,5702,DB00193,10046735,174,19146,48,8654,0.002148228,1.638475339,1.182851455,2.307473751,0.010316283,DB0019310046735_,4.574031798,0.493766138,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,5703,DB00338,10046735,324,33350,140,22132,1.72301934651417e-05,1.535812578,1.254849237,1.887629853,0.0001751,DB0033810046735_,8.650154455,0.429059608,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,5704,DB00425,10046735,90,12605,29,7455,0.004105506,1.835426215,1.194622826,2.896929696,0.017446161,DB0042510046735_,4.048635639,0.607276724,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,zolpidem,DB00425
,5705,DB00476,10046735,151,17106,23,6154,3.02273372994454e-05,2.36188971,1.514987936,3.842941038,0.000285801,DB0047610046735_,8.160216328,0.859462023,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,duloxetine,DB00476
,5706,DB00586,10046735,92,7017,32,2773,0.616008689,1.136133613,0.750382807,1.760521468,0.757244868,DB0058610046735_,0.278068607,0.12763093,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,diclofenac,DB00586
,5709,DB01611,10046735,140,11773,12,2349,0.002821096,2.327696582,1.288384562,4.620432249,0.012854152,DB0161110046735_,4.354088373,0.844879187,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxychloroquine,DB01611
,5710,DB06643,10046735,278,52143,19,7496,0.000782348,2.103390745,1.32060321,3.548962183,0.004490452,DB0664310046735_,5.405801857,0.743550683,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,5711,DB00186,10047943,48,16853,29,9979,1,0.980052283,0.605115395,1.6129342,1,DB0018610047943_,0,-0.020149359,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,lorazepam,DB00186
,5712,DB00193,10047943,58,19262,19,8683,0.267138137,1.376109726,0.807052643,2.448420585,0.429410832,DB0019310047943_,0.845341167,0.319260479,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,tramadol,DB00193
,5713,DB00338,10047943,114,33560,65,22207,0.359363031,1.160495364,0.847984476,1.599883659,0.529105575,DB0033810047943_,0.636567292,0.148846952,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,omeprazole,DB00338
,5715,DB00476,10047943,55,17202,10,6167,0.047833264,1.971805089,0.994622587,4.341437498,0.121045283,DB0047610047943_,2.111590568,0.678949412,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,duloxetine,DB00476
,5721,DB00186,10048959,261,16640,98,9910,7.27563635280892e-05,1.586088955,1.251012794,2.024381758,0.00060663,DB0018610048959_,7.407591539,0.461271209,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,5722,DB00193,10048959,379,18941,134,8568,0.015956931,1.279363802,1.046122253,1.572514048,0.051726946,DB0019310048959_,2.961776439,0.246362924,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,5723,DB00338,10048959,745,32929,370,21902,4.65154113849535e-06,1.33923668,1.179277013,1.522956173,5.55248677680973e-05,DB0033810048959_,9.79867957,0.29209981,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,5724,DB00425,10048959,190,12505,86,7398,0.044481885,1.307013874,1.006156668,1.70932997,0.114560686,DB0042510048959_,2.166650589,0.26774505,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,5725,DB00476,10048959,287,16970,60,6117,7.95668614856889e-05,1.7242257,1.299238169,2.320878967,0.00065613,DB0047610048959_,7.329151341,0.54477808,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,5726,DB00586,10048959,158,6951,62,2743,1,1.005643404,0.742456527,1.376428464,1,DB0058610048959_,0,0.005627539,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,5728,DB01238,10048959,52,5198,19,3483,0.027837384,1.833740889,1.063894813,3.290509279,0.07986309,DB0123810048959_,2.527441486,0.606358082,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,5729,DB01611,10048959,260,11653,29,2332,0.001773394,1.794106309,1.216165712,2.739750381,0.00880952,DB0161110048959_,4.731922289,0.58450702,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,5730,DB06643,10048959,275,52146,67,7448,0.000207697,0.586249635,0.446841509,0.778506829,0.001486741,DB0664310048959_,6.511168956,-0.534009581,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,5731,DB00186,10050584,131,16770,35,9973,1.12162646824451e-05,2.225787671,1.521437617,3.33422024,0.000119845,DB0018610050584_,9.029308545,0.800110862,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,5732,DB00193,10050584,162,19158,59,8643,0.166162881,1.238698634,0.913066525,1.700387415,0.3056397,DB0019310050584_,1.185348321,0.21406134,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,5733,DB00338,10050584,300,33374,136,22136,0.000222185,1.463086961,1.18994395,1.806499073,0.001574159,DB0033810050584_,6.454034264,0.38054856,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,5734,DB00425,10050584,131,12564,40,7444,0.000168889,1.940332915,1.350746385,2.841849938,0.001249785,DB0042510050584_,6.684783969,0.662859564,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,5735,DB00476,10050584,129,17128,29,6148,0.023145169,1.596579451,1.05935577,2.481172836,0.069255025,DB0047610050584_,2.669959579,0.467863498,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,5736,DB00586,10050584,58,7051,18,2787,0.443265919,1.27357526,0.738142559,2.30124419,0.611421321,DB0058610050584_,0.491968998,0.241828111,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,diclofenac,DB00586
,5739,DB01611,10050584,104,11809,16,2345,0.389063471,1.290730058,0.75677853,2.346079257,0.558964408,DB0161110050584_,0.581669479,0.255207995,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxychloroquine,DB01611
,5740,DB06643,10050584,150,52271,16,7499,0.291784497,1.344967345,0.801036779,2.415108851,0.457206032,DB0664310050584_,0.782621154,0.296369734,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,5741,DB00016,10003239,72,2690,34,2256,0.005658319,1.775791588,1.160529232,2.765576161,0.022589448,DB0001610003239_,3.790272398,0.574246289,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,erythropoietin,DB00016
,5742,DB00126,10003239,332,9839,110,5835,5.82349805239903e-08,1.789865189,1.434745207,2.246953456,1.10800323059941e-06,DB0012610003239_,13.71295105,0.582140303,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,5743,DB00169,10003239,1354,37337,337,17838,4.52304961605814e-29,1.919512383,1.700053262,2.171991291,9.39828926150894e-27,DB0016910003239_,59.92926983,0.652071187,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,5744,DB00404,10003239,502,19390,131,9731,3.43870727361633e-12,1.923106868,1.581058993,2.352730876,1.41560564897424e-10,DB0040410003239_,22.67829347,0.653942039,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,5745,DB00421,10003239,251,8652,72,5180,8.82307843867521e-09,2.087052237,1.596082928,2.757924748,2.00878836518474e-07,DB0042110003239_,15.42056391,0.735752658,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,spironolactone,DB00421
,5746,DB00437,10003239,157,6764,202,11344,0.015312564,1.303454217,1.048965148,1.617426172,0.050126502,DB0043710003239_,2.993205429,0.265017831,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,allopurinol,DB00437
,5748,DB00996,10003239,964,37989,318,22107,1.48586830060429e-19,1.764077623,1.550729028,2.011057741,1.47381314269373e-17,DB0099610003239_,38.75609356,0.56762796,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,5750,DB08877,10003239,74,3215,48,3181,0.027876884,1.525256975,1.042795824,2.24901941,0.079958957,DB0887710003239_,2.526241808,0.422162904,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ruxolitinib,DB08877
,5753,DB00126,10005191,40,10131,23,5922,1,1.016595061,0.593382855,1.78054075,1,DB0012610005191_,0,0.016458868,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,ascorbic acid,DB00126
,5754,DB00169,10005191,141,38550,64,18111,0.880781984,1.035013247,0.764591968,1.41424226,0.950123172,DB0016910005191_,0.051163648,0.034414226,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,5755,DB00264,10005191,102,29505,61,24831,0.040308301,1.407231009,1.014338899,1.966575927,0.106263847,DB0026410005191_,2.24183016,0.34162395,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,5756,DB00404,10005191,93,19799,24,9838,0.003057551,1.925425472,1.217567629,3.156783885,0.013736897,DB0040410005191_,4.287669852,0.655146968,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,5758,DB00437,10005191,31,6890,28,11518,0.021346201,1.850666236,1.073113646,3.205486072,0.065113488,DB0043710005191_,2.731623568,0.615545702,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,5759,DB00695,10005191,135,27914,84,20444,0.244859452,1.177038263,0.889274532,1.565550651,0.403620388,DB0069510005191_,0.907280476,0.163001337,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,5761,DB00996,10005191,129,38824,71,22354,0.825434641,1.046133942,0.776738346,1.418710017,0.90772946,DB0099610005191_,0.096808897,0.045101409,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,5766,DB00126,10006451,150,10021,56,5889,0.003570507,1.57406292,1.148639057,2.183500898,0.015573015,DB0012610006451_,4.162215667,0.453660124,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,5767,DB00169,10006451,472,38219,117,18058,5.0856197112306e-11,1.906083934,1.55237227,2.356040921,1.73830317437837e-09,DB0016910006451_,20.17035639,0.645050841,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,5768,DB00264,10006451,300,29307,138,24754,1.40933213236302e-09,1.836159082,1.494837236,2.264594288,3.79163716470441e-08,DB0026410006451_,17.08788285,0.607675935,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,metoprolol,DB00264
,5769,DB00338,10006451,455,33219,143,22129,1.97916029691047e-16,2.119547667,1.75129553,2.578183871,1.42722162974737e-14,DB0033810006451_,31.88046166,0.751202701,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,omeprazole,DB00338
,5770,DB00404,10006451,210,19682,29,9833,8.20009349946342e-14,3.617545654,2.444032693,5.539891648,4.25546806778669e-12,DB0040410006451_,26.18281636,1.2857958,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,alprazolam,DB00404
,5771,DB00421,10006451,139,8764,37,5215,4.45291700300708e-06,2.23533393,1.543019291,3.311016603,5.34207774641903e-05,DB0042110006451_,9.837310797,0.804390626,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,spironolactone,DB00421
,5772,DB00437,10006451,93,6828,60,11486,6.18051280965894e-09,2.607265013,1.861870401,3.674903433,1.45895625686471e-07,DB0043710006451_,15.74037436,0.958301784,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,allopurinol,DB00437
,5773,DB00695,10006451,396,27653,131,20397,7.60163726822901e-17,2.229649256,1.823991974,2.740174217,5.72518726634382e-15,DB0069510006451_,32.79390114,0.801844289,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,furosemide,DB00695
,5775,DB00996,10006451,400,38553,101,22324,1.75539687465258e-15,2.293223839,1.83801835,2.883743658,1.14777628980704e-13,DB0099610006451_,29.7957798,0.829958617,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,gabapentin,DB00996
,5780,DB00126,10007882,87,10084,53,5892,0.86040835,0.959146067,0.672832242,1.378451325,0.934268331,DB0012610007882_,0.06799159,-0.041711904,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,5781,DB00169,10007882,264,38427,143,18032,0.182241027,0.866325211,0.703574307,1.070291863,0.326685491,DB0016910007882_,1.118757374,-0.143494909,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,5782,DB00264,10007882,206,29401,157,24735,0.369016493,1.103834058,0.891879574,1.36840055,0.538612239,DB0026410007882_,0.618759375,0.098789627,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,metoprolol,DB00264
,5783,DB00338,10007882,220,33454,134,22138,0.479043162,1.086459706,0.871873655,1.357946077,0.64420595,DB0033810007882_,0.439736806,0.082924434,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,omeprazole,DB00338
,5784,DB00404,10007882,89,19803,38,9824,0.508524408,1.161868828,0.785687706,1.747890413,0.669030686,DB0040410007882_,0.401925352,0.150029767,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,alprazolam,DB00404
,5785,DB00421,10007882,123,8780,50,5202,0.026409767,1.45747086,1.039030001,2.071347623,0.076671164,DB0042110007882_,2.568229598,0.376702646,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,spironolactone,DB00421
,5786,DB00437,10007882,68,6853,105,11441,0.636208751,1.081186352,0.783711123,1.483153953,0.773906548,DB0043710007882_,0.256304152,0.078058912,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,allopurinol,DB00437
,5787,DB00695,10007882,318,27731,230,20298,0.896316024,1.01201536,0.850548545,1.20560981,0.956301489,DB0069510007882_,0.044682051,0.011943749,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,furosemide,DB00695
,5789,DB00996,10007882,242,38711,156,22269,0.273062448,0.892399511,0.726200049,1.099234066,0.43604061,DB0099610007882_,0.830019899,-0.113841365,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,gabapentin,DB00996
,5794,DB00126,10008531,121,10050,65,5880,0.646630774,1.089144398,0.797719034,1.498544715,0.782032295,DB0012610008531_,0.245859241,0.085392432,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,5795,DB00169,10008531,388,38303,136,18039,0.002992556,1.343642485,1.10150635,1.647089199,0.013481761,DB0016910008531_,4.30641754,0.295384199,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,5796,DB00264,10008531,207,29400,174,24718,1,1.000179389,0.813031174,1.231632735,1,DB0026410008531_,0,0.000179373,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,5797,DB00421,10008531,87,8816,43,5209,0.362759737,1.195482597,0.818951502,1.768168566,0.532273931,DB0042110008531_,0.630597014,0.178549951,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,5798,DB00437,10008531,58,6863,119,11427,0.212042493,0.81155304,0.58151435,1.12158665,0.363831642,DB0043710008531_,1.011064039,-0.208805534,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,5799,DB00695,10008531,243,27806,144,20384,0.044000169,1.237065219,1.001713968,1.532270184,0.113603893,DB0069510008531_,2.175037502,0.212741815,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,5801,DB00996,10008531,255,38698,143,22282,0.834613514,1.026762686,0.832808134,1.269921206,0.91418995,DB0099610008531_,0.089716907,0.026410829,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,5803,DB08877,10008531,20,3269,38,3191,0.017059455,0.513811965,0.282609107,0.907734367,0.054541138,DB0887710008531_,2.908800044,-0.665897908,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,5805,DB00016,10012174,43,2719,35,2255,1,1.018912435,0.634551715,1.646149275,1,DB0001610012174_,0,0.018735818,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,erythropoietin,DB00016
,5806,DB00126,10012174,152,10019,94,5851,0.689635294,0.944328771,0.723846164,1.23727164,0.812888491,DB0012610012174_,0.207161336,-0.057280899,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ascorbic acid,DB00126
,5807,DB00169,10012174,536,38155,274,17901,0.255038889,0.917787003,0.791087323,1.066655388,0.415741791,DB0016910012174_,0.877690905,-0.085789938,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,5808,DB00264,10012174,487,29120,418,24474,0.762095026,0.979183831,0.856487362,1.11987015,0.868205343,DB0026410012174_,0.141327023,-0.021035879,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,5809,DB00338,10012174,494,33180,323,21949,0.88554795,1.011725844,0.876607804,1.16891533,0.952411128,DB0033810012174_,0.04875848,0.011657629,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,5810,DB00404,10012174,222,19670,87,9775,0.068200359,1.268022356,0.984090959,1.646097167,0.158060788,DB0040410012174_,1.844775587,0.237458486,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,alprazolam,DB00404
,5811,DB00421,10012174,167,8736,115,5137,0.212974679,0.853932391,0.667628035,1.095319869,0.364990347,DB0042110012174_,1.007884372,-0.157903256,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,spironolactone,DB00421
,5812,DB00437,10012174,149,6772,210,11336,0.123052677,1.187687708,0.954113353,1.475456839,0.245806104,DB0043710012174_,1.403212248,0.172008315,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,allopurinol,DB00437
,5813,DB00695,10012174,495,27554,401,20127,0.133115154,0.901688785,0.787809432,1.032478727,0.260085618,DB0069510012174_,1.346744401,-0.103485846,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,5815,DB00996,10012174,451,38502,245,22180,0.47629906,1.060450661,0.904818302,1.245162059,0.641676008,DB0099610012174_,0.443671763,0.05869397,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,5817,DB08877,10012174,25,3264,50,3179,0.003435484,0.48703414,0.28793541,0.804554777,0.01509683,DB0887710012174_,4.193270491,-0.719421055,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ruxolitinib,DB08877
,5820,DB00126,10013911,68,10103,50,5895,0.21476812,0.793571207,0.541919409,1.168957786,0.367154242,DB0012610013911_,1.001973241,-0.231212005,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,5821,DB00169,10013911,243,38448,114,18061,1,1.001312128,0.79774679,1.263004204,1,DB0016910013911_,0,0.001311268,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,5822,DB00264,10013911,155,29452,141,24751,0.52002473,0.923832234,0.730143892,1.16967521,0.679146897,DB0026410013911_,0.386917832,-0.079224789,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,5823,DB00338,10013911,182,33492,150,22122,0.04895763,0.801437297,0.641634118,1.002260393,0.123037699,DB0033810013911_,2.095264471,-0.221348542,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,5824,DB00404,10013911,89,19803,36,9826,0.341228027,1.226648392,0.823492444,1.861903054,0.510380897,DB0040410013911_,0.672597975,0.204285566,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,5825,DB00421,10013911,46,8857,26,5226,0.903238793,1.043919975,0.631030538,1.761507022,0.957348417,DB0042110013911_,0.043587882,0.042982834,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,5826,DB00437,10013911,40,6881,60,11486,0.60571529,1.112813507,0.725797481,1.690042012,0.748782165,DB0043710013911_,0.289307173,0.106891499,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,5827,DB00695,10013911,117,27932,95,20433,0.486058967,0.900935738,0.68094556,1.194507592,0.649960453,DB0069510013911_,0.430843759,-0.104321347,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,5829,DB00996,10013911,137,38816,98,22327,0.10348458,0.804122621,0.615573274,1.053652013,0.216260088,DB0099610013911_,1.531273485,-0.218003508,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,5833,DB00016,10013968,134,2628,104,2186,0.640749597,1.07176544,0.81793517,1.407397224,0.777638893,DB0001610013968_,0.25149301,0.069307232,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,erythropoietin,DB00016
,5834,DB00169,10013968,1506,37185,673,17502,0.281283497,1.053247596,0.959337782,1.157243626,0.445259664,DB0016910013968_,0.809097652,0.051878339,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,5835,DB00264,10013968,1541,28066,1171,23721,0.007592828,1.112215641,1.028143816,1.203399515,0.028566782,DB0026410013968_,3.555510704,0.106354099,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,5836,DB00421,10013968,982,7921,423,4829,7.91396670120381e-09,1.41526464,1.254314375,1.598745041,1.81834453445054e-07,DB0042110013968_,15.52016916,0.347316539,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,5837,DB00437,10013968,410,6511,481,11065,9.72447277468658e-08,1.448498572,1.262053283,1.66209134,1.76220452866347e-06,DB0043710013968_,13.24894496,0.370527552,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,5838,DB00695,10013968,2744,25305,1516,19012,1.4121175188254e-20,1.359887349,1.273155948,1.452930206,1.56613961950741e-18,DB0069510013968_,40.99791792,0.307401865,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,5839,DB00905,10013968,46,2672,18,907,0.663673331,0.867527044,0.490357953,1.598342855,0.795143512,DB0090510013968_,0.229232662,-0.142108593,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bimatoprost,DB00905
,5840,DB01005,10013968,40,1055,45,822,0.117550653,0.692715947,0.436339033,1.09626723,0.237504816,DB0100510013968_,1.437567377,-0.367135253,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxyurea,DB01005
,5841,DB08877,10013968,132,3157,140,3089,0.535893079,0.922577896,0.71789392,1.18506889,0.692354366,DB0887710013968_,0.367657365,-0.080583467,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ruxolitinib,DB08877
,5851,DB00695,10014080,35,28014,23,20505,0.790539718,1.113875198,0.639613072,1.975054251,0.886547197,DB0069510014080_,0.120420915,0.107845105,NA,10014080,Ecchymosis,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,5857,DB00016,10016173,64,2698,44,2246,0.379376945,1.210817001,0.808529345,1.827776545,0.549396602,DB0001610016173_,0.59893469,0.191295339,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,erythropoietin,DB00016
,5858,DB00126,10016173,425,9746,213,5732,0.06540297,1.173544264,0.989798259,1.394574437,0.1531371,DB0012610016173_,1.876421683,0.160028455,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ascorbic acid,DB00126
,5859,DB00338,10016173,1173,32501,589,21683,2.19572554930618e-08,1.328626643,1.200558426,1.471603,4.56317897115817e-07,DB0033810016173_,14.60007613,0.28414581,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,5860,DB00404,10016173,623,19269,200,9662,2.48433726042744e-08,1.561923674,1.327204956,1.844490485,5.10561414310674e-07,DB0040410016173_,14.4877549,0.445918186,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,5861,DB00421,10016173,315,8588,181,5071,0.813030887,1.027621866,0.850277485,1.244866509,0.89954571,DB0042110016173_,0.10586541,0.027247264,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,spironolactone,DB00421
,5862,DB00437,10016173,219,6702,285,11261,0.005860817,1.291092729,1.074782572,1.549348009,0.023239035,DB0043710016173_,3.761921872,0.255488937,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,allopurinol,DB00437
,5863,DB00905,10016173,45,2673,19,906,0.468409852,0.802802623,0.457351127,1.4614217,0.634915581,DB0090510016173_,0.454263232,-0.219646395,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,bimatoprost,DB00905
,5864,DB00996,10016173,1462,37491,689,21736,8.71545178613021e-06,1.230174233,1.121155098,1.350888483,9.62747006507387e-05,DB0099610016173_,9.248304988,0.207155812,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,5866,DB08877,10016173,96,3193,61,3168,0.007522076,1.561333922,1.116530533,2.197525688,0.028364369,DB0887710016173_,3.562621532,0.445540534,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ruxolitinib,DB08877
,5868,DB00421,10016256,667,8236,318,4934,0.001153906,1.256524507,1.092539815,1.447415918,0.006200005,DB0042110016256_,5.083205118,0.228349582,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,5869,DB00437,10016256,467,6454,695,10851,0.052242228,1.129713851,0.99849025,1.27739884,0.129247208,DB0043710016256_,2.046028365,0.121964372,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,5870,DB01005,10016256,69,1026,51,816,0.776094318,1.076007291,0.729227542,1.596279129,0.87794888,DB0100510016256_,0.13016691,0.073257238,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,hydroxyurea,DB01005
,5871,DB08877,10016256,281,3008,284,2945,0.724886764,0.968709931,0.812009739,1.155621782,0.838634345,DB0887710016256_,0.17598049,-0.03179006,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,5873,DB00016,10018838,35,2727,23,2267,0.42730847,1.264987426,0.724239257,2.249471843,0.595890008,DB0001610018838_,0.517699178,0.235062182,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,erythropoietin,DB00016
,5874,DB00126,10018838,36,10135,24,5921,0.687847675,0.876330944,0.508040239,1.537025632,0.811821478,DB0012610018838_,0.208474817,-0.13201147,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,ascorbic acid,DB00126
,5875,DB00169,10018838,102,38589,52,18123,0.665358618,0.921223658,0.653061285,1.313113723,0.796382198,DB0016910018838_,0.22767606,-0.08205243,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,5876,DB00264,10018838,80,29527,63,24829,0.737033972,1.067816601,0.757613926,1.510638712,0.848327581,DB0026410018838_,0.16448842,0.065616004,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,metoprolol,DB00264
,5877,DB00338,10018838,90,33584,54,22218,0.609572779,1.102626582,0.777948746,1.575740014,0.751961715,DB0033810018838_,0.285069867,0.097695135,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,omeprazole,DB00338
,5878,DB00404,10018838,33,19859,18,9844,0.766640494,0.90877937,0.496759618,1.715202474,0.871570485,DB0040410018838_,0.13745854,-0.095652932,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,alprazolam,DB00404
,5879,DB00421,10018838,35,8868,16,5236,0.46863234,1.291562187,0.695463551,2.501595781,0.635095824,DB0042110018838_,0.453979388,0.255852483,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,spironolactone,DB00421
,5880,DB00437,10018838,47,6874,41,11505,0.002691862,1.918609771,1.233615639,2.994309625,0.012377431,DB0043710018838_,4.39188053,0.651600846,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,allopurinol,DB00437
,5881,DB00695,10018838,109,27940,56,20472,0.032861523,1.426161831,1.023556053,2.006308447,0.09098969,DB0069510018838_,2.397009075,0.354986802,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,furosemide,DB00695
,5883,DB00996,10018838,82,38871,47,22378,1,1.004411168,0.693088784,1.470439369,1,DB0099610018838_,0,0.004401467,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,gabapentin,DB00996
,5885,DB08877,10018838,38,3251,39,3190,0.908870468,0.956068848,0.593518312,1.538859366,0.95913476,DB0887710018838_,0.041723693,-0.044925351,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,ruxolitinib,DB08877
,5887,DB00126,10018884,136,10035,113,5832,0.006532806,0.699497048,0.539797462,0.907784822,0.02534251,DB0012610018884_,3.675272054,-0.357393705,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ascorbic acid,DB00126
,5888,DB00264,10018884,385,29222,326,24566,0.939604544,0.992812947,0.853521128,1.155348186,0.979030204,DB0026410018884_,0.021192785,-0.007213005,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,metoprolol,DB00264
,5889,DB00338,10018884,390,33284,265,22007,0.748121042,0.97305691,0.829552511,1.142816974,0.856928275,DB0033810018884_,0.154401057,-0.02731271,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,omeprazole,DB00338
,5890,DB00404,10018884,156,19736,68,9794,0.393277359,1.138444015,0.850057341,1.538455827,0.563186891,DB0040410018884_,0.57414375,0.129662431,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,alprazolam,DB00404
,5891,DB00421,10018884,148,8755,80,5172,0.580430156,1.092889943,0.825171739,1.456352118,0.728953804,DB0042110018884_,0.316144919,0.088825512,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,spironolactone,DB00421
,5892,DB00437,10018884,182,6739,241,11305,0.01932783,1.266825376,1.036718651,1.545932119,0.060179105,DB0043710018884_,2.810430088,0.236514067,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,allopurinol,DB00437
,5893,DB00695,10018884,474,27575,355,20173,0.749683232,0.976790645,0.848401482,1.125446577,0.858175409,DB0069510018884_,0.152946761,-0.023482933,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,furosemide,DB00695
,5895,DB01005,10018884,48,1047,40,827,0.826747457,0.947904297,0.603516403,1.49556877,0.908621952,DB0100510018884_,0.095826166,-0.053501735,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,hydroxyurea,DB01005
,5896,DB08877,10018884,167,3122,161,3068,0.909793918,1.019325789,0.811149005,1.281231353,0.959437782,DB0887710018884_,0.04140781,0.019141418,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ruxolitinib,DB08877
,5899,DB00126,10028391,60,10111,26,5919,0.218729235,1.350903522,0.838468072,2.23300889,0.371978387,DB0012610028391_,0.988919525,0.300773644,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,5900,DB00169,10028391,260,38431,76,18099,0.000167387,1.611125186,1.242446884,2.110122986,0.001239721,DB0016910028391_,6.692868896,0.476932808,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,5901,DB00264,10028391,157,29450,88,24804,0.002451358,1.502620043,1.149535333,1.974770732,0.011487601,DB0026410028391_,4.466487009,0.40721028,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,5902,DB00338,10028391,191,33483,85,22187,0.002026966,1.488968161,1.146647875,1.947071019,0.009830943,DB0033810028391_,4.622220411,0.398083371,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,5903,DB00404,10028391,110,19782,38,9824,0.054286026,1.437547698,0.985047853,2.139048877,0.133014048,DB0040410028391_,2.017300536,0.362938674,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,5904,DB00421,10028391,55,8848,27,5225,0.492072323,1.202956949,0.744864276,1.986063249,0.65501299,DB0042110028391_,0.423100211,0.18478265,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,spironolactone,DB00421
,5905,DB00437,10028391,30,6891,36,11510,0.202686042,1.391846495,0.827190496,2.326579115,0.352154844,DB0043710028391_,1.043684301,0.330631279,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,allopurinol,DB00437
,5906,DB00695,10028391,164,27885,82,20446,0.004374858,1.466438626,1.117525582,1.93693412,0.018357782,DB0069510028391_,3.997701727,0.382836758,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,5908,DB00996,10028391,212,38741,84,22341,0.003609487,1.455411319,1.124647406,1.897924514,0.015703944,DB0099610028391_,4.153843385,0.375288554,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,5912,DB00016,10030124,64,2698,43,2247,0.326390884,1.239521323,0.825574872,1.877063576,0.494919634,DB0001610030124_,0.703359885,0.214725275,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,5913,DB00126,10030124,153,10018,60,5885,0.008057141,1.497942756,1.102316958,2.05805251,0.029961371,DB0012610030124_,3.507846371,0.404092671,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,5914,DB00169,10030124,483,38208,221,17954,0.77594726,1.02700311,0.873154622,1.210914426,0.877822795,DB0016910030124_,0.130310533,0.02664496,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,5915,DB00264,10030124,427,29180,293,24599,0.007461469,1.228543136,1.05525351,1.431805137,0.02817479,DB0026410030124_,3.569327689,0.205829025,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,5916,DB00338,10030124,467,33207,254,22018,0.011481789,1.219054106,1.04302361,1.427379962,0.039770552,DB0033810030124_,3.22462854,0.198075235,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,5917,DB00421,10030124,324,8579,147,5105,0.007568997,1.311517396,1.072512722,1.60984766,0.028496896,DB0042110030124_,3.557960118,0.271184785,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,5918,DB00437,10030124,141,6780,153,11393,0.000255487,1.548487669,1.220533484,1.963666713,0.001768161,DB0043710030124_,6.337815201,0.437278757,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,5919,DB00695,10030124,1012,27037,564,19964,1.03715413643523e-07,1.324913692,1.192081274,1.47367302,1.87236239534342e-06,DB0069510030124_,13.18830961,0.281347319,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,5922,DB08877,10030124,37,3252,41,3188,0.649066203,0.884696006,0.550013839,1.418698917,0.783967703,DB0887710030124_,0.243387455,-0.122511189,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,5924,DB00126,10035528,98,10073,74,5871,0.095730332,0.771904785,0.563941125,1.060361699,0.204367251,DB0012610035528_,1.587836652,-0.258894072,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,ascorbic acid,DB00126
,5925,DB00169,10035528,354,38337,246,17929,2.9092195336387e-06,0.672980838,0.569726883,0.795923845,3.68897143075566e-05,DB0016910035528_,10.20757779,-0.396038423,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,5926,DB00338,10035528,311,33363,304,21968,1.44163543096603e-06,0.673638424,0.572710861,0.792356635,1.98863223841207e-05,DB0033810035528_,10.82547838,-0.395061775,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,omeprazole,DB00338
,5927,DB00404,10035528,133,19759,63,9799,0.819480504,1.046952704,0.769328675,1.437813704,0.903789257,DB0040410035528_,0.101159068,0.045883758,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,alprazolam,DB00404
,5928,DB00421,10035528,100,8803,56,5196,0.802823144,1.054024538,0.751047972,1.492057051,0.893313651,DB0042110035528_,0.112817527,0.05261573,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,spironolactone,DB00421
,5929,DB00695,10035528,322,27727,255,20273,0.351159481,0.923276548,0.780135519,1.093559386,0.520874064,DB0069510035528_,0.652246986,-0.07982647,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,furosemide,DB00695
,5931,DB01005,10035528,32,1063,26,841,1,0.973736069,0.557335784,1.715590817,1,DB0100510035528_,0,-0.026614988,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,hydroxyurea,DB01005
,5933,DB00016,10037660,67,2695,64,2226,0.424541594,0.864718153,0.601687215,1.243692703,0.593350893,DB0001610037660_,0.52196933,-0.14535166,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,5934,DB00126,10037660,206,9965,162,5783,0.004472285,0.73798681,0.596171822,0.914695983,0.018683093,DB0012610037660_,3.980136264,-0.303829327,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,5935,DB00264,10037660,465,29142,462,24430,0.010452032,0.843757256,0.739365405,0.962911523,0.036866818,DB0026410037660_,3.300443362,-0.169890437,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,5936,DB00421,10037660,220,8683,121,5131,0.570516111,1.074412192,0.854339787,1.356393144,0.721031637,DB0042110037660_,0.327072263,0.071773714,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,5937,DB00437,10037660,226,6695,357,11189,0.514624861,1.057984716,0.889115084,1.256934536,0.67450623,DB0043710037660_,0.393774367,0.056365887,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,5938,DB00695,10037660,617,27432,432,20096,0.487072224,1.046299479,0.922453591,1.187581822,0.650956828,DB0069510037660_,0.429311956,0.045259633,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,5940,DB00996,10037660,651,38302,475,21950,8.2106918271304e-05,0.785435353,0.695901189,0.88693866,0.000674282,DB0099610037660_,7.301862054,-0.241517125,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,5941,DB01005,10037660,23,1072,35,832,0.015127723,0.510206112,0.285436644,0.895950504,0.049651272,DB0100510037660_,3.002731269,-0.672940493,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,hydroxyurea,DB01005
,5942,DB08877,10037660,68,3221,145,3084,3.93472263641476e-08,0.449069768,0.330139507,0.605786354,7.76166487791084e-07,DB0887710037660_,14.06889879,-0.800577018,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,5944,DB00016,10038153,38,2724,34,2256,0.811774534,0.925646783,0.565245035,1.521282964,0.89891282,DB0001610038153_,0.106569223,-0.077262561,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,erythropoietin,DB00016
,5945,DB00126,10038153,64,10107,36,5909,0.917360911,1.039367613,0.679529456,1.612054097,0.963310853,DB0012610038153_,0.037379123,0.038612464,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,ascorbic acid,DB00126
,5946,DB00169,10038153,179,38512,94,18081,0.397752684,0.894035643,0.692249478,1.160927956,0.567460004,DB0016910038153_,0.566585009,-0.112009635,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,5947,DB00264,10038153,127,29480,106,24786,1,1.007341852,0.77178586,1.31700518,1,DB0026410038153_,0,0.007315032,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,metoprolol,DB00264
,5948,DB00338,10038153,141,33533,77,22195,0.187960896,1.211995147,0.911209017,1.622407344,0.334005954,DB0033810038153_,1.09659646,0.192267884,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,omeprazole,DB00338
,5949,DB00404,10038153,62,19830,29,9833,0.911247076,1.060122023,0.671277702,1.710413246,0.960120631,DB0040410038153_,0.040696345,0.058384018,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,alprazolam,DB00404
,5950,DB00421,10038153,31,8872,26,5226,0.215883468,0.702363402,0.403066792,1.233029842,0.368449904,DB0042110038153_,0.998450523,-0.353304342,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,spironolactone,DB00421
,5951,DB00437,10038153,42,6879,74,11472,0.847555747,0.946521655,0.631429004,1.402468559,0.923670252,DB0043710038153_,0.079400141,-0.054961429,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,allopurinol,DB00437
,5952,DB00695,10038153,141,27908,102,20426,0.948179373,1.011751009,0.778125303,1.319359313,0.986615527,DB0069510038153_,0.013474852,0.011682502,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,furosemide,DB00695
,5954,DB00996,10038153,126,38827,79,22346,0.56151776,0.917932384,0.687066912,1.232645866,0.713915755,DB0099610038153_,0.336990314,-0.085631547,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,gabapentin,DB00996
,5956,DB08877,10038153,58,3231,52,3177,0.700669867,1.096711026,0.738617423,1.632026535,0.820068904,DB0887710038153_,0.198366913,0.092315724,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,ruxolitinib,DB08877
,5958,DB00016,10047895,87,2675,65,2225,0.562790563,1.113250687,0.793870108,1.567741006,0.714992585,DB0001610047895_,0.335483107,0.107284283,NA,10047895,Weight decreased,10022891,Investigations,Inv,erythropoietin,DB00016
,5959,DB00126,10047895,248,9923,167,5778,0.163980668,0.864721492,0.705821622,1.06148951,0.302736576,DB0012610047895_,1.194892236,-0.145347798,NA,10047895,Weight decreased,10022891,Investigations,Inv,ascorbic acid,DB00126
,5960,DB00169,10047895,888,37803,456,17719,0.123721577,0.912773773,0.813196368,1.025597699,0.246701688,DB0016910047895_,1.399575412,-0.091267213,NA,10047895,Weight decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,5961,DB00338,10047895,742,32932,565,21707,0.010939732,0.865645299,0.773802379,0.968789668,0.038248317,DB0033810047895_,3.263655731,-0.144280039,NA,10047895,Weight decreased,10022891,Investigations,Inv,omeprazole,DB00338
,5962,DB00421,10047895,234,8669,135,5117,0.869947926,1.023123888,0.821859336,1.277769477,0.942182195,DB0042110047895_,0.05955661,0.022860582,NA,10047895,Weight decreased,10022891,Investigations,Inv,spironolactone,DB00421
,5963,DB00437,10047895,135,6786,249,11297,0.365244444,0.902566381,0.724858401,1.11994229,0.534854672,DB0043710047895_,0.625760211,-0.10251304,NA,10047895,Weight decreased,10022891,Investigations,Inv,allopurinol,DB00437
,5965,DB00996,10047895,601,38352,365,22060,0.419099628,0.947108374,0.82930509,1.082803525,0.588164858,DB0099610047895_,0.530747999,-0.054341753,NA,10047895,Weight decreased,10022891,Investigations,Inv,gabapentin,DB00996
,5970,DB00169,10064990,31,38660,24,18151,0.081313069,0.606440309,0.344394649,1.080201502,0.180566878,DB0016910064990_,1.711654054,-0.500148974,NA,10064990,Skin abrasion,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,5996,DB00482,10017944,54,8205,14,3057,0.273634484,1.436996182,0.785805722,2.805763855,0.436649005,DB0048210017944_,0.828625599,0.36255495,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,celecoxib,DB00482
,5997,DB00482,10061822,81,8178,19,3052,0.070752565,1.59100232,0.954315235,2.782475324,0.162606556,DB0048210061822_,1.816421762,0.464364207,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,5998,DB00374,10019301,38,17678,15,5709,0.522486839,0.818116893,0.439267446,1.602259497,0.681010004,DB0037410019301_,0.384178282,-0.200750052,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,treprostinil,DB00374
,5999,DB00559,10019301,39,9620,12,3294,0.872455818,1.112827703,0.57002538,2.33749685,0.944171158,DB0055910019301_,0.057447818,0.106904256,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,bosentan,DB00559
,6002,DB00331,10047700,958,23988,484,20268,1.61943543089737e-20,1.672364019,1.495190977,1.872509445,1.76993182125312e-18,DB0033110047700_,40.87559065,0.514238206,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,6003,DB00497,10016322,279,18988,180,16195,0.003990047,1.321993623,1.090841165,1.605459072,0.017049238,DB0049710016322_,4.071649796,0.279140918,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,6004,DB08900,10011906,53,958,17,420,0.289245092,1.366570298,0.767912704,2.548906692,0.454358776,DB0890010011906_,0.788868137,0.312304169,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,teduglutide,DB08900
,6006,DB00295,10021143,83,14580,97,9505,0.000118296,0.557860944,0.410578093,0.756562662,0.000920621,DB0029510021143_,6.990462013,-0.583645551,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,6008,DB00341,10021143,58,11347,32,5036,0.359385507,0.804456315,0.513045587,1.281923886,0.529120357,DB0034110021143_,0.636539354,-0.217588615,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,6011,DB00451,10021143,225,47046,83,15336,0.353004609,0.883664224,0.683639818,1.15159392,0.522759861,DB0045110021143_,0.648633077,-0.123678125,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,6012,DB00497,10021143,150,19117,123,16252,0.807435103,1.036753391,0.810560961,1.328070082,0.896013834,DB0049710021143_,0.109799426,0.036094091,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,6013,DB00863,10021143,61,10612,41,5799,0.301142296,0.813044571,0.537664559,1.24067838,0.467406273,DB0086310021143_,0.760556435,-0.206969348,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,6014,DB00904,10021143,220,22849,179,14277,0.009676826,0.767980124,0.626847277,0.941829819,0.034669851,DB0090410021143_,3.361884822,-0.263991426,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,6016,DB00996,10021143,156,38797,135,22290,0.000610081,0.663933156,0.523590706,0.842743659,0.003649935,DB0099610021143_,5.613045947,-0.409573804,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,6017,DB01175,10021143,42,10682,34,4858,0.017764171,0.561840441,0.348461497,0.911725359,0.056311049,DB0117510021143_,2.876864503,-0.576537382,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,6020,DB00295,10033425,199,14464,101,9501,0.037501348,1.294219527,1.012081656,1.663577551,0.100594237,DB0029510033425_,2.296660305,0.257907831,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,6021,DB00333,10033425,43,3028,33,3119,0.248238533,1.342121426,0.83044389,2.186920329,0.407618294,DB0033310033425_,0.897424098,0.294251515,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,methadone,DB00333
,6022,DB00341,10033425,259,11146,74,4994,0.00049391,1.568146734,1.203937519,2.063594054,0.003061171,DB0034110033425_,5.788957756,0.449894498,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,6024,DB00422,10033425,62,3373,23,2926,0.000395176,2.338042828,1.423863025,3.964946242,0.002536244,DB0042210033425_,5.97707087,0.849314181,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,methylphenidate,DB00422
,6025,DB00451,10033425,1248,46023,258,15161,1.81267724643199e-12,1.593408366,1.39066857,1.831447036,7.8108559708959e-11,DB0045110033425_,23.27292147,0.465875349,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,6026,DB00863,10033425,254,10419,103,5737,0.009946213,1.357836864,1.073205165,1.728209579,0.035408167,DB0086310033425_,3.340812781,0.305892892,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,6027,DB00904,10033425,473,22596,185,14271,1.7447899010604e-08,1.614754758,1.357651302,1.926956396,3.70450747571669e-07,DB0090410033425_,14.80854534,0.479183092,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,6028,DB00916,10033425,75,5248,28,2403,0.39353921,1.22643327,0.782602737,1.972241892,0.563469776,DB0091610033425_,0.573641584,0.204110176,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,metronidazole,DB00916
,6029,DB01175,10033425,204,10520,39,4853,5.86061248654883e-08,2.412902598,1.703139125,3.498259551,1.11427821559041e-06,DB0117510033425_,13.7073037,0.88083042,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,6032,DB00295,10061818,191,14472,124,9478,0.953830981,1.008787655,0.799272742,1.27702181,0.991769906,DB0029510061818_,0.008264148,0.008749268,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,6034,DB00341,10061818,75,11330,37,5031,0.608150718,0.900096633,0.598468201,1.374984537,0.750956786,DB0034110061818_,0.286407171,-0.105253151,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,6035,DB00351,10061818,34,632,38,826,0.543933367,1.16926311,0.705233164,1.931874461,0.699048456,DB0035110061818_,0.358035218,0.15637373,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,megestrol acetate,DB00351
,6037,DB00497,10061818,278,18989,235,16140,0.96443365,1.005491424,0.841039268,1.202933801,1,DB0049710061818_,0,0.005476401,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,6038,DB00863,10061818,109,10564,77,5763,0.089723582,0.772278492,0.570495187,1.04973292,0.194777862,DB0086310061818_,1.635895536,-0.258410053,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,6039,DB00904,10061818,549,22520,336,14120,0.753126413,1.024470964,0.891289348,1.178911331,0.861080903,DB0090410061818_,0.149566815,0.024176346,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,6041,DB00996,10061818,280,38673,200,22225,0.019751948,0.804581629,0.668129117,0.970287161,0.061187973,DB0099610061818_,2.793804622,-0.217432852,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,6042,DB01175,10061818,74,10650,58,4834,0.00243668,0.579126166,0.404400005,0.832794461,0.011430025,DB0117510061818_,4.47151165,-0.546234923,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,6043,DB08865,10061818,96,1115,92,879,0.219401355,0.822694512,0.602945616,1.123001394,0.372771703,DB0886510061818_,0.986789104,-0.195170336,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,crizotinib,DB08865
,6059,DB06228,10014498,34,15878,38,16038,0.723900716,0.903762359,0.551576453,1.475402049,0.837715468,DB0622810014498_,0.177076773,-0.10118883,NA,10014498,Embolic stroke,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,6061,DB00635,10019717,43,33010,38,23756,0.368761025,0.814361063,0.513890773,1.295175426,0.538403797,DB0063510019717_,0.619146449,-0.205351445,NA,10019717,Hepatitis,10019805,Hepatobiliary disorders,Hepat,prednisone,DB00635
,6071,DB00904,10023126,43,23026,30,14426,0.718225313,0.89800101,0.55015876,1.483276844,0.833604562,DB0090410023126_,0.181996135,-0.107584086,NA,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,ondansetron,DB00904
,6075,DB00327,10021015,53,6085,21,4241,0.032100619,1.758899185,1.041303667,3.075054244,0.089325086,DB0032710021015_,2.415472909,0.56468815,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,hydromorphone,DB00327
,6080,DB00327,10047700,350,5788,173,4089,0.000149539,1.429208474,1.182376329,1.73263536,0.001123518,DB0032710047700_,6.791290593,0.357120777,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,hydromorphone,DB00327
,6087,DB00999,10002198,59,21371,32,12207,0.913172204,1.053142354,0.673284518,1.674902906,0.961104948,DB0099910002198_,0.039671669,0.051778413,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,hydrochlorothiazide,DB00999
,6088,DB01076,10002198,37,25710,40,25543,0.733430118,0.919012136,0.571299198,1.474788972,0.845381756,DB0107610002198_,0.167966972,-0.084455951,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,atorvastatin,DB01076
,6089,DB01229,10002198,31,5710,26,2683,0.032484245,0.560308779,0.321187574,0.984573399,0.090168265,DB0122910002198_,2.406077738,-0.579267257,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,paclitaxel,DB01229
,6092,DB00999,10005734,94,21336,53,12186,1,1.012978206,0.715326408,1.44760216,1,DB0099910005734_,0,0.012894711,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,6093,DB01076,10005734,85,25662,123,25460,0.008150151,0.685625705,0.513497527,0.911859177,0.030249465,DB0107610005734_,3.498276781,-0.37742342,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,6097,DB00999,10024855,134,21296,73,12166,0.77229885,1.048654678,0.781994688,1.415742779,0.875371939,DB0099910024855_,0.133106409,0.047508084,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,6098,DB01076,10024855,158,25589,160,25423,0.866223503,0.981091559,0.781913719,1.230891318,0.939418442,DB0107610024855_,0.062494274,-0.019089492,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,6100,DB14513,10024855,48,7129,27,3537,0.623251687,0.882047299,0.538364291,1.472852068,0.763328313,DB1451310024855_,0.270067048,-0.125509598,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,6101,DB00734,10037844,42,4008,29,4873,0.022372418,1.760703864,1.069048538,2.936598496,0.067454224,DB0073410037844_,2.69630608,0.565713652,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,risperidone,DB00734
,6102,DB00999,10037844,636,20794,290,11949,0.001263084,1.260195514,1.093028208,1.45575789,0.006665147,DB0099910037844_,5.010863305,0.231266879,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,6103,DB01076,10037844,627,25120,570,25013,0.121195405,1.095297174,0.974945579,1.230748643,0.24314935,DB0107610037844_,1.414079414,0.091025718,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,6104,DB01229,10037844,150,5591,41,2668,0.001258474,1.745733705,1.22437423,2.538190632,0.006644368,DB0122910037844_,5.013985648,0.557174929,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,paclitaxel,DB01229
,6105,DB14513,10037844,205,6972,80,3484,0.064615381,1.280527717,0.980915874,1.685033002,0.151779739,DB1451310037844_,1.885324894,0.247272272,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,magnesium,DB14513
,6106,DB01267,10013983,20,2832,37,3678,0.228092119,0.702053202,0.385181553,1.244450052,0.383497064,DB0126710013983_,0.958423313,-0.353746091,NA,10013983,Dystonia,10029205,Nervous system disorders,Nerv,paliperidone,DB01267
,6108,DB06643,10021519,178,52243,20,7495,0.334294423,1.276826284,0.801708514,2.142413477,0.503386436,DB0664310021519_,0.686397142,0.244377533,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,6109,DB06643,10044034,711,51710,96,7419,0.629980913,1.062605819,0.856310719,1.330997291,0.768972244,DB0664310044034_,0.262700404,0.060724211,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,6110,DB06643,10064658,697,51724,246,7269,1.08339242211889e-29,0.398206326,0.343078957,0.463329098,2.34378352390083e-27,DB0664310064658_,61.318031,-0.920785,NA,10064658,Osteonecrosis of jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,6116,DB00374,10012174,313,17403,103,5621,0.862961226,0.981514308,0.781504819,1.241162461,0.936576069,DB0037410012174_,0.065524533,-0.018658687,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,treprostinil,DB00374
,6117,DB00820,10012174,223,11692,88,5728,0.08837034,1.24142012,0.963708156,1.610904788,0.192533002,DB0082010012174_,1.647487703,0.216255983,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,tadalafil,DB00820
,6118,DB00374,10012735,2277,15439,623,5101,7.81889773556996e-05,1.207539478,1.098371682,1.328909639,0.000645882,DB0037410012735_,7.344893371,0.1885848,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,6119,DB00559,10012735,563,9096,151,3155,0.006127573,1.293195024,1.073573252,1.56534461,0.024071625,DB0055910012735_,3.726721508,0.257115919,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,6120,DB00820,10012735,1679,10236,523,5293,5.16280391513244e-23,1.660001334,1.49543055,1.844807891,7.03131092794073e-21,DB0082010012735_,46.40391379,0.506818406,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,6121,DB00374,10016173,531,17185,158,5566,0.368337469,1.088502172,0.907237287,1.311870326,0.538039422,DB0037410016173_,0.619823446,0.084802597,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,6122,DB00820,10016173,440,11475,140,5676,4.24514495961719e-06,1.554548487,1.278876302,1.899026998,5.11265224575202e-05,DB0082010016173_,9.881207165,0.441185141,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,tadalafil,DB00820
,6123,DB00559,10016256,544,9115,156,3150,0.044888651,1.205087624,1.001928649,1.456063725,0.115364831,DB0055910016256_,2.159655727,0.186552281,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,6124,DB00820,10016256,1014,10901,401,5415,0.00017653,1.256045874,1.112627909,1.420069197,0.001297743,DB0082010016256_,6.647128545,0.227968591,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,6125,DB00374,10016825,657,17059,209,5515,0.871958248,1.01627841,0.865782585,1.196771386,0.943737786,DB0037410016825_,0.057906921,0.016147337,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,treprostinil,DB00374
,6126,DB00559,10016825,165,9494,59,3247,0.757508943,0.956456416,0.704362554,1.314144917,0.864441903,DB0055910016825_,0.145671179,-0.044520057,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,bosentan,DB00559
,6127,DB00820,10016825,574,11341,159,5657,1.55513641304159e-11,1.80067949,1.5034905,2.16653512,5.74515258141926e-10,DB0082010016825_,21.27749446,0.588164088,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,tadalafil,DB00820
,6128,DB00374,10019303,322,17394,99,5625,0.688981991,1.051796249,0.83540589,1.333990057,0.81249806,DB0037410019303_,0.207641753,0.050499416,NA,10019303,Heart rate increased,10022891,Investigations,Inv,treprostinil,DB00374
,6129,DB00559,10019303,148,9511,33,3273,0.025228925,1.543256704,1.049901418,2.329542749,0.074003156,DB0055910019303_,2.603647531,0.433894926,NA,10019303,Heart rate increased,10022891,Investigations,Inv,bosentan,DB00559
,6130,DB00820,10019303,241,11674,76,5740,0.00069773,1.559141682,1.197511715,2.049489472,0.00408005,DB0082010019303_,5.501646105,0.444135466,NA,10019303,Heart rate increased,10022891,Investigations,Inv,tadalafil,DB00820
,6131,DB00374,10024855,269,17447,107,5617,0.069456883,0.809376166,0.643216115,1.024486648,0.160329689,DB0037410024855_,1.830523026,-0.211491494,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,6132,DB00559,10024855,149,9510,42,3264,0.277954583,1.217580401,0.857180371,1.762529028,0.441665833,DB0055910024855_,0.817201717,0.196865612,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,bosentan,DB00559
,6133,DB00820,10024855,237,11678,72,5744,0.000295652,1.619015315,1.236217843,2.142300849,0.00199407,DB0082010024855_,6.217577748,0.481818134,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,6134,DB00374,10028813,2239,15477,495,5229,4.38941893858719e-17,1.528176516,1.378694628,1.696154449,3.39340814119895e-15,DB0037410028813_,33.31694163,0.424075205,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,6135,DB00820,10028813,1573,10342,362,5454,3.23186492581977e-48,2.291452409,2.032916589,2.587888936,1.82687246398221e-45,DB0082010028813_,103.0137237,0.829185856,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,6136,DB00374,10048959,527,17189,146,5578,0.101159084,1.17133577,0.9707866,1.420404523,0.212555779,DB0037410048959_,1.548550837,0.158144781,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,6137,DB00559,10048959,227,9432,65,3241,0.221471365,1.199995178,0.904258116,1.611133299,0.375354622,DB0055910048959_,0.97988404,0.182317539,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,6138,DB00820,10048959,472,11443,173,5643,0.000856985,1.345434661,1.124520743,1.615637428,0.00484844,DB0082010048959_,5.329098322,0.296717129,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,6139,DB00374,10050584,108,17608,22,5702,0.051200482,1.589635184,0.997126003,2.644349521,0.127303375,DB0037410050584_,2.061182263,0.463504546,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,6140,DB00559,10050584,75,9584,13,3293,0.019413964,1.982279479,1.090037327,3.899909868,0.060393636,DB0055910050584_,2.806871537,0.684247434,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,bosentan,DB00559
,6141,DB00820,10050584,82,11833,25,5791,0.0387107,1.605173245,1.013759332,2.625515409,0.103065156,DB0082010050584_,2.272393908,0.473231692,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,tadalafil,DB00820
,6142,DB00374,10063829,94,17622,32,5692,0.835240938,0.948825958,0.628433334,1.466762161,0.914705667,DB0037410063829_,0.089152941,-0.052529893,NA,10063829,Device malfunction,10077536,Product issues,Prod,treprostinil,DB00374
,6143,DB00559,10063829,36,9623,18,3288,0.209753082,0.683384848,0.377429502,1.280170282,0.360881018,DB0055910063829_,1.019206964,-0.380697111,NA,10063829,Device malfunction,10077536,Product issues,Prod,bosentan,DB00559
,6144,DB00820,10063829,50,11865,17,5799,0.240341799,1.43746782,0.814148727,2.660911102,0.398231503,DB0082010063829_,0.920721776,0.362883107,NA,10063829,Device malfunction,10077536,Product issues,Prod,tadalafil,DB00820
,6146,DB00005,10042496,46,128036,25,42394,0.053648762,0.6092447,0.366511655,1.03492621,0.131858217,DB0000510042496_,2.026028044,-0.495535286,NA,10042496,Sunburn,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,6154,DB00864,10010185,26,6843,34,8358,0.896707734,0.933994524,0.537662182,1.60501743,0.956301489,DB0086410010185_,0.044682051,-0.068284704,NA,10010185,Complications of transplanted kidney,10022117,"Injury, poisoning and procedural complications",Inj&P,tacrolimus,DB00864
,6165,DB00864,10040047,100,6769,117,8275,0.783524027,1.044878943,0.790359819,1.379195883,0.882171087,DB0086410040047_,0.125369266,0.043901035,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,6166,DB00959,10040047,116,7962,110,4892,0.001443941,0.647978128,0.493579822,0.851031071,0.007452347,DB0095910040047_,4.899226213,-0.433898337,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,6197,DB00005,10058467,78,128004,36,42383,0.104063969,0.717399881,0.477384197,1.096669291,0.217149322,DB0000510058467_,1.527170043,-0.33212188,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,etanercept,DB00005
,6200,DB00338,10058467,42,33632,38,22234,0.170835732,0.730703747,0.459679532,1.164920961,0.311942842,DB0033810058467_,1.164935308,-0.313747173,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,omeprazole,DB00338
,6203,DB00635,10058467,38,33015,38,23756,0.163102695,0.719566836,0.446554972,1.159470289,0.301530057,DB0063510058467_,1.198885578,-0.329105864,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,6205,DB00695,10058467,50,27999,34,20494,0.825210222,1.076418486,0.682276335,1.716973662,0.90753962,DB0069510058467_,0.097018056,0.073639314,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,furosemide,DB00695
,6206,DB01076,10058467,40,25707,34,25549,0.561245895,1.169235119,0.721363023,1.905000074,0.713690929,DB0107610058467_,0.337305283,0.15634979,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,atorvastatin,DB01076
,6209,DB00958,10002034,343,4251,127,2458,2.27173789239621e-05,1.561548527,1.262185423,1.941415328,0.00022285,DB0095810002034_,8.409012111,0.445677974,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,carboplatin,DB00958
,6210,DB00958,10021097,81,4513,70,2515,0.009912191,0.644863722,0.460718686,0.904593527,0.035301396,DB0095810021097_,3.34383278,-0.438716269,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,carboplatin,DB00958
,6211,DB01248,10021097,42,2658,38,1336,0.011657597,0.555601597,0.347809171,0.890170494,0.040236353,DB0124810021097_,3.21298438,-0.587703794,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,docetaxel,DB01248
,6212,DB00958,10042772,62,4532,20,2565,0.027880997,1.754397169,1.042446285,3.074275367,0.07996203,DB0095810042772_,2.526203383,0.562125304,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,carboplatin,DB00958
,6214,DB00213,10038695,195,18700,195,13226,0.000760418,0.707292857,0.576191844,0.868182311,0.004383724,DB0021310038695_,5.429856612,-0.346310474,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,6215,DB00327,10038695,85,6053,67,4195,0.455040455,0.879249064,0.629182705,1.232934526,0.62261463,DB0032710038695_,0.473827522,-0.128687072,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydromorphone,DB00327
,6216,DB00332,10038695,57,2627,61,1595,0.002771332,0.567443824,0.386208995,0.832612374,0.0126675,DB0033210038695_,4.368715657,-0.566613524,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipratropium,DB00332
,6217,DB00368,10038695,26,634,59,739,0.004960951,0.51388592,0.307006064,0.839597377,0.020338464,DB0036810038695_,3.895241384,-0.665753984,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,norepinephrine,DB00368
,6218,DB00572,10038695,35,2867,20,2106,0.412079905,1.285426468,0.719448869,2.357144739,0.581464764,DB0057210038695_,0.542204903,0.251090545,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atropine,DB00572
,6219,DB00601,10038695,30,875,29,882,0.895422243,1.042748383,0.599137607,1.817122697,0.95615204,DB0060110038695_,0.044838341,0.041859903,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,linezolid,DB00601
,6221,DB00668,10038695,39,10052,38,4265,0.00039066,0.435482276,0.270922828,0.700568627,0.002514321,DB0066810038695_,5.985752616,-0.831301181,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,6223,DB00688,10038695,118,6372,146,5232,0.001118299,0.663653999,0.514723791,0.854210726,0.006039253,DB0068810038695_,5.109475021,-0.409994351,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolate mofetil,DB00688
,6224,DB00760,10038695,35,745,47,968,0.909721164,0.967598786,0.599622963,1.54860692,0.959437782,DB0076010038695_,0.04140781,-0.032937755,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,meropenem,DB00760
,6225,DB00818,10038695,44,1376,44,1633,0.44869592,1.186704346,0.758348561,1.857039419,0.616307993,DB0081810038695_,0.484008452,0.171180008,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,propofol,DB00818
,6227,DB00877,10038695,33,1075,32,1399,0.255682482,1.341892715,0.794174554,2.269763365,0.416412161,DB0087710038695_,0.876079738,0.294081091,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sirolimus,DB00877
,6228,DB00887,10038695,56,2285,41,1774,0.836150979,1.0604029,0.692614301,1.635480666,0.915356757,DB0088710038695_,0.088441391,0.05864893,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bumetanide,DB00887
,6229,DB00904,10038695,233,22836,194,14262,0.003681801,0.750112997,0.616591184,0.913337179,0.01596044,DB0090410038695_,4.137642102,-0.287531421,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,6230,DB00927,10038695,81,7416,88,4928,0.001544112,0.611693812,0.445645497,0.838635208,0.007877146,DB0092710038695_,4.843789569,-0.491523429,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,6233,DB01141,10038695,16,382,43,562,0.053973888,0.547733425,0.283665515,1.009599551,0.132443564,DB0114110038695_,2.021598658,-0.60196656,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,micafungin,DB01141
,6237,DB01373,10038695,70,22650,32,7349,0.107659374,0.709763421,0.460465704,1.115636022,0.222671962,DB0137310038695_,1.502055611,-0.342823574,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,6238,DB01413,10038695,50,1170,85,1574,0.212334615,0.791416162,0.541946001,1.145549577,0.364190235,DB0141310038695_,1.010078923,-0.233931329,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cefepime,DB01413
,6240,DB11089,10038695,134,10041,115,8292,0.797743938,0.962238807,0.743086006,1.247703531,0.890712121,DB1108910038695_,0.115734,-0.038492619,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,6241,DB00327,10040047,116,6022,81,4181,1,0.9942884,0.740022945,1.341225512,1,DB0032710040047_,0,-0.005727974,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,hydromorphone,DB00327
,6242,DB00332,10040047,36,2648,30,1626,0.250409802,0.736928582,0.439366084,1.243958123,0.410158695,DB0033210040047_,0.891211134,-0.305264295,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ipratropium,DB00332
,6243,DB00368,10040047,34,626,46,752,0.645186608,0.887983453,0.545379118,1.433462074,0.780932492,DB0036810040047_,0.247266571,-0.11880217,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,norepinephrine,DB00368
,6244,DB00572,10040047,39,2863,44,2082,0.056259021,0.644642548,0.406327929,1.019301781,0.136563977,DB0057210040047_,1.99096208,-0.439059305,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,atropine,DB00572
,6247,DB00668,10040047,75,10016,40,4263,0.260949976,0.798079118,0.535731878,1.204598375,0.42244758,DB0066810040047_,0.861689911,-0.225547541,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,epinephrine,DB00668
,6249,DB00688,10040047,89,6401,82,5296,0.487382978,0.898008863,0.65617612,1.230242925,0.651206587,DB0068810040047_,0.42892835,-0.107575341,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,6250,DB00760,10040047,35,745,45,970,1,1.012672316,0.625069046,1.62899318,1,DB0076010040047_,0,0.012592694,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,meropenem,DB00760
,6251,DB00787,10040047,225,16775,333,16915,1.04230381952068e-05,0.681325716,0.571917573,0.8104685,0.000112558,DB0078710040047_,9.092039672,-0.383714797,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,acyclovir,DB00787
,6255,DB00887,10040047,53,2288,47,1768,0.540658639,0.871404148,0.574175776,1.326045022,0.696167356,DB0088710040047_,0.362165194,-0.137649405,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,bumetanide,DB00887
,6256,DB00904,10040047,391,22678,368,14088,1.80532651265459e-08,0.660074906,0.570094517,0.764315068,3.8191555239538e-07,DB0090410040047_,14.77806632,-0.415401957,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,6257,DB00927,10040047,122,7375,108,4908,0.035160622,0.751788533,0.573927399,0.985792322,0.095741939,DB0092710040047_,2.346098842,-0.285300201,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,famotidine,DB00927
,6260,DB01141,10040047,19,379,34,571,0.665549871,0.842077305,0.446658392,1.544737971,0.796538571,DB0114110040047_,0.227479725,-0.171883458,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,micafungin,DB01141
,6261,DB01190,10040047,34,4900,28,2257,0.027531504,0.559391738,0.328350202,0.960139918,0.079171334,DB0119010040047_,2.536140995,-0.580905267,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,clindamycin,DB01190
,6263,DB01373,10040047,130,22590,74,7307,0.000161761,0.568256405,0.423371245,0.767534944,0.00120303,DB0137310040047_,6.722911665,-0.565182545,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,calcium,DB01373
,6264,DB01413,10040047,70,1150,74,1585,0.14110966,1.303624255,0.918054909,1.849650183,0.271448141,DB0141310040047_,1.303984166,0.265148274,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,cefepime,DB01413
,6266,DB11089,10040047,180,9995,214,8193,0.000274934,0.689497337,0.561086515,0.846508893,0.001879736,DB1108910040047_,6.276623882,-0.371792444,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,docusate,DB11089
,6276,DB00005,10033557,279,127803,50,42369,2.32428165657342e-05,1.84977073,1.364734332,2.552982639,0.000227072,DB0000510033557_,8.390243054,0.615061702,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,etanercept,DB00005
,6277,DB00051,10033557,95,25636,39,11381,0.708779858,1.081403462,0.737042258,1.614055214,0.826231393,DB0005110033557_,0.190880408,0.078259699,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,adalimumab,DB00051
,6278,DB00073,10033557,37,7369,25,6382,0.372920788,1.281745073,0.750275512,2.223934387,0.542627581,DB0007310033557_,0.611332049,0.248222488,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,rituximab,DB00073
,6279,DB00563,10033557,137,46509,25,15323,0.004657655,1.805357957,1.172144662,2.888208506,0.019308644,DB0056310033557_,3.947202427,0.590758886,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,methotrexate,DB00563
,6283,DB00051,10013709,5266,20465,1700,9720,3.782133761282e-38,1.471233844,1.385458444,1.56281938,1.39039700580835e-35,DB0005110013709_,80.26088893,0.386101399,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,6284,DB00588,10013709,716,15808,308,8160,0.00853763,1.199945081,1.045581104,1.379657125,0.031373076,DB0058810013709_,3.461805191,0.18227579,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,6286,DB00115,10022004,132,18293,43,10429,0.00116444,1.750069151,1.230825951,2.532319038,0.006247831,DB0011510022004_,5.075520887,0.559655302,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,6287,DB00390,10008190,47,4098,50,3251,0.151479543,0.745751352,0.488556242,1.13665294,0.285965439,DB0039010008190_,1.25188432,-0.293363042,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,digoxin,DB00390
,6290,DB05812,10016256,9,173,592,7361,0.250494961,0.646911345,0.289339049,1.265677668,0.410259832,DB0581210016256_,0.890964584,-0.435546019,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,abiraterone,DB05812
,6293,DB08910,10011906,1131,15613,1551,15937,3.06649298940945e-13,0.744348978,0.686659172,0.806713704,1.47624117631186e-11,DB0891010011906_,24.93893691,-0.295245297,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,6294,DB08910,10035664,1214,15530,1569,15919,5.86710077872618e-09,0.793129646,0.732872309,0.858162089,1.38934003575511e-07,DB0891010035664_,15.78926681,-0.231768583,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,6295,DB00983,10069293,158,3343,65,1675,0.216568598,1.217850064,0.901008901,1.661937955,0.369362114,DB0098310069293_,0.995977778,0.197087062,NA,10069293,Product container issue,10077536,Product issues,Prod,formoterol,DB00983
,6296,DB14512,10057362,35,4809,22,2390,0.398828931,0.790705805,0.449874336,1.418271973,0.56870472,DB1451210057362_,0.564393925,-0.234829308,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,mometasone furoate,DB14512
,6297,DB00005,10042682,280,127802,55,42364,0.000231278,1.687470742,1.259756809,2.296759944,0.001626529,DB0000510042682_,6.421307159,0.523230806,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,6298,DB00190,10013916,116,3181,121,4553,0.018935378,1.372087908,1.04990462,1.792465825,0.05917798,DB0019010013916_,2.827205767,0.3163336,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,6299,DB00285,10013916,31,10920,21,3697,0.016267057,0.499774294,0.277757782,0.916372845,0.052520288,DB0028510013916_,2.946555755,-0.693598694,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,6300,DB00413,10013916,36,2163,24,1183,0.496436729,0.82044902,0.473588071,1.444942305,0.65859988,DB0041310013916_,0.417639091,-0.197903503,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,pramipexole,DB00413
,6301,DB00190,10030312,13,3284,39,4635,0.016203379,0.470506417,0.230067644,0.902159628,0.052351524,DB0019010030312_,2.949774231,-0.753945682,NA,10030312,On and off phenomenon,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,6305,DB00335,10054112,58,8408,39,5426,0.835508646,0.959766268,0.62770345,1.481556039,0.914862473,DB0033510054112_,0.088981527,-0.041065495,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,atenolol,DB00335
,6306,DB00668,10054112,56,10035,23,4280,1,1.038422519,0.627775137,1.770799334,1,DB0066810054112_,0,0.037702753,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,epinephrine,DB00668
,6307,DB00758,10054112,85,8215,79,9995,0.097665006,1.309054514,0.950846579,1.803895472,0.207410898,DB0075810054112_,1.573053439,0.269305132,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,clopidogrel,DB00758
,6308,DB00927,10054112,98,7399,57,4959,0.410865653,1.152266048,0.821251259,1.629880115,0.580218325,DB0092710054112_,0.544350823,0.14173048,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,famotidine,DB00927
,6309,DB00996,10054112,328,38625,176,22249,0.45785903,1.073509006,0.890452886,1.297662948,0.625169456,DB0099610054112_,0.469732536,0.070932727,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,gabapentin,DB00996
,6310,DB01075,10054112,86,19862,50,11047,0.788766455,0.956658435,0.666861709,1.385238466,0.88555981,DB0107510054112_,0.121535281,-0.044308864,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,diphenhydramine,DB01075
,6312,DB01373,10054112,135,22585,51,7330,0.348046803,0.859136501,0.617431762,1.211544974,0.517575752,DB0137310054112_,0.658599383,-0.151827463,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,calcium,DB01373
,6313,DB01377,10054112,47,3749,32,2638,0.90907206,1.03349022,0.643752502,1.678604946,0.959155407,DB0137710054112_,0.041702166,0.032941637,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,magnesium oxide,DB01377
,6314,DB06404,10054112,52,3017,9,891,0.165182346,1.706081773,0.828902493,3.954027169,0.304379261,DB0640410054112_,1.189480787,0.53419938,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,human c1-esterase inhibitor,DB06404
,6316,DB09153,10054112,194,7605,146,5553,0.781333813,0.970224557,0.776440315,1.214532082,0.880918086,DB0915310054112_,0.126790636,-0.030227733,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,sodium chloride,DB09153
,6317,DB00999,10000060,155,21275,71,12168,0.127204617,1.248625199,0.936060734,1.679273509,0.25173719,DB0099910000060_,1.379369634,0.222043105,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,6318,DB08908,10000060,94,10579,25,3254,0.587666902,1.156526717,0.736024935,1.880214609,0.734656832,DB0890810000060_,0.308351784,0.145421304,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,6319,DB00999,10002855,387,21043,114,12125,5.70040900919648e-11,1.956013378,1.581428538,2.435021728,1.93710731488985e-09,DB0099910002855_,20.06207005,0.670908411,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,6320,DB00999,10003988,505,20925,195,12044,1.78083887567422e-06,1.49058605,1.259099687,1.770410732,2.39067159586807e-05,DB0099910003988_,10.64135114,0.399169364,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,6321,DB00999,10011469,67,21363,7,12232,1.75104440877403e-07,5.48106108,2.517298951,14.16066451,3.01124412232166e-06,DB0099910011469_,12.71315723,1.70129871,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,6323,DB00999,10017577,369,21061,140,12099,2.281593904411e-05,1.514131671,1.241474739,1.855198921,0.000223608,DB0099910017577_,8.405615536,0.41484212,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,6324,DB08908,10017577,289,10384,100,3179,0.302659206,0.884748861,0.699862362,1.126117403,0.469012924,DB0890810017577_,0.757124954,-0.122451447,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,6325,DB00999,10020772,450,20980,215,12024,0.030877737,1.199582296,1.015739135,1.420085224,0.086655375,DB0099910020772_,2.445816233,0.18197341,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,hydrochlorothiazide,DB00999
,6326,DB08908,10020772,77,10596,12,3267,0.023774704,1.978242117,1.068349444,3.999545383,0.070724093,DB0890810020772_,2.648968985,0.682208631,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,dimethyl fumarate,DB08908
,6327,DB00999,10022437,420,21010,155,12084,1.73923992733518e-06,1.558463771,1.291395746,1.888618783,2.34200417469289e-05,DB0099910022437_,10.66191842,0.443700574,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,6328,DB08908,10022437,109,10564,31,3248,0.764276483,1.081060296,0.718078865,1.670815832,0.869785784,DB0890810022437_,0.139508323,0.077942315,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,dimethyl fumarate,DB08908
,6331,DB00999,10033557,195,21235,37,12202,8.4535667788346e-12,3.028296999,2.120441218,4.431881586,3.26527557357336e-10,DB0099910033557_,21.84250677,1.108000415,female,10033557,Palpitations,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,6332,DB08908,10033557,52,10621,6,3273,0.018720343,2.670700116,1.146079362,7.614426942,0.058655885,DB0890810033557_,2.836067372,0.982340654,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,dimethyl fumarate,DB08908
,6333,DB00999,10037087,510,20920,195,12044,8.71121870524268e-07,1.505703669,1.272095759,1.787874583,1.26925933296732e-05,DB0099910037087_,11.27449194,0.409260343,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,6334,DB08908,10037087,340,10333,61,3218,4.49060086634461e-05,1.735695185,1.314254525,2.325665409,0.000403333,DB0890810037087_,7.815747684,0.551408016,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,dimethyl fumarate,DB08908
,6335,DB00999,10038776,36,21394,16,12223,0.471656321,1.285497338,0.695062747,2.482065339,0.637812805,DB0099910038776_,0.449710447,0.251145677,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,6337,DB00999,10060800,100,21330,41,12198,0.079166445,1.394793067,0.959918179,2.059864494,0.177002359,DB0099910060800_,1.73159222,0.332746066,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,hydrochlorothiazide,DB00999
,6338,DB08908,10060800,171,10502,38,3241,0.070567002,1.388686103,0.969938138,2.033955938,0.162300709,DB0890810060800_,1.818304437,0.328358051,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,dimethyl fumarate,DB08908
,6339,DB00999,10061623,140,21290,67,12172,0.246628764,1.194608248,0.885878762,1.624746559,0.40570999,DB0099910061623_,0.902116686,0.177818306,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,6340,DB08908,10061623,53,10620,11,3268,0.300228801,1.482593112,0.764233884,3.151756072,0.466373976,DB0890810061623_,0.762767444,0.393792657,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,6341,DB00999,10074903,114,21316,40,12199,0.007088865,1.631012617,1.12770061,2.402380697,0.027057404,DB0099910074903_,3.609794601,0.489201059,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,6342,DB08908,10074903,50,10623,13,3266,0.657521099,1.18246862,0.631873777,2.375980757,0.790692277,DB0890810074903_,0.234846417,0.167604304,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,dimethyl fumarate,DB08908
,6344,DB00563,10003988,611,46035,186,15162,0.363692113,1.081921823,0.915706494,1.283223377,0.533272169,DB0056310003988_,0.628723349,0.078738926,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,6345,DB00563,10008469,116,46530,29,15319,0.210340495,1.316894612,0.869974449,2.053494016,0.361605699,DB0056310008469_,1.017200889,0.275276398,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,6346,DB00563,10022075,93,46553,11,15337,0.000379533,2.785456978,1.486506935,5.773337305,0.002455825,DB0056310022075_,6.009292365,1.024411945,female,10022075,Injection site induration,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,6347,DB00563,10022094,230,46416,28,15320,2.70515742354609e-08,2.711290034,1.825963513,4.171795171,5.50348783884744e-07,DB0056310022094_,14.41271361,0.997424549,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,6348,DB00563,10022095,755,45891,73,15275,2.61536853053368e-32,3.442616706,2.70260676,4.44237144,6.67426813835706e-30,DB0056310022095_,67.17929323,1.236231853,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,6349,DB00563,10022112,218,46428,18,15330,1.20348283101718e-11,3.998990842,2.47019139,6.877849186,4.54831721255017e-10,DB0056310022112_,21.51109361,1.38604204,female,10022112,Injection site warmth,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,6350,DB00005,10028411,575,127507,225,42194,0.036488931,0.845702639,0.723332205,0.991432832,0.098562487,DB0000510028411_,2.317064544,-0.167587471,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,6351,DB00563,10028411,299,46347,94,15254,0.725361174,1.046932395,0.827049096,1.335444746,0.839011572,DB0056310028411_,0.17553078,0.04586436,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,6352,DB00563,10028836,215,46431,58,15290,0.205612148,1.220693037,0.908952369,1.661925518,0.35596805,DB0056310028836_,1.0329143,0.199418761,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,6353,DB00563,10033371,1905,44741,473,14875,1.04253410495897e-08,1.338983293,1.207990818,1.486528618,2.3371436203707e-07,DB0056310033371_,15.26916614,0.291910589,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,6354,DB00005,10022081,1247,126835,286,42133,6.66223135123791e-09,1.448348316,1.272079612,1.653664678,1.55452064862218e-07,DB0000510022081_,15.67692842,0.370423815,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,6355,DB00005,10000087,735,127347,192,42227,0.002951579,1.269356507,1.081084666,1.496365366,0.013321127,DB0000510000087_,4.318404,0.238510084,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,6356,DB00563,10000087,341,46305,84,15264,0.017711608,1.33816047,1.050330174,1.721187078,0.056174381,DB0056310000087_,2.879294485,0.291295887,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,6357,DB00005,10009866,49,128033,28,42391,0.024528836,0.579417743,0.35698422,0.95756282,0.072448691,DB0000510009866_,2.624876681,-0.545731571,NA,10009866,Cold sweat,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,6359,DB00563,10016322,467,46179,107,15241,0.000547761,1.440424238,1.164196599,1.795803705,0.003327069,DB0056310016322_,5.705663464,0.36493768,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,6360,DB00563,10048959,904,45742,206,15142,7.19169500610576e-07,1.452633383,1.245861013,1.700149086,1.06889286534063e-05,DB0056310048959_,11.44630206,0.373378035,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,6361,DB00005,10061224,395,127687,121,42298,0.475476683,1.081395376,0.87972162,1.337277401,0.641091646,DB0000510061224_,0.444582859,0.078252222,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,6362,DB00563,10061224,89,46557,24,15324,0.4453404,1.220569575,0.770081406,2.004839563,0.613309841,DB0056310061224_,0.48888502,0.199317615,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,6365,DB00682,10000081,372,19087,169,16195,6.25457761777104e-12,1.867630558,1.551053145,2.256323234,2.47966172976036e-10,DB0068210000081_,22.11772878,0.624670546,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,6366,DB06605,10000081,138,13935,90,12943,0.009370093,1.424155846,1.082903327,1.880640109,0.033791987,DB0660510000081_,3.387531562,0.353579249,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,6367,DB00682,10006093,64,19395,69,16295,0.163073113,0.77929306,0.545419877,1.112008648,0.301496572,DB0068210006093_,1.198996632,-0.249368103,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,warfarin,DB00682
,6368,DB06605,10006093,51,14022,33,13000,0.125381357,1.432789908,0.906317486,2.293481218,0.249188988,DB0660510006093_,1.389543681,0.359623528,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,apixaban,DB06605
,6373,DB00207,10001053,47,9033,41,5414,0.097011358,0.687110519,0.44163628,1.072780265,0.206297766,DB0020710001053_,1.578434689,-0.375260127,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,6374,DB00319,10001053,31,1361,27,1826,0.109131144,1.540187769,0.884932384,2.695888476,0.224735979,DB0031910001053_,1.492828992,0.431904337,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,piperacillin,DB00319
,6376,DB00787,10001053,37,16963,28,17220,0.264694601,1.341432655,0.798584088,2.276690022,0.426665708,DB0078710001053_,0.851754459,0.293738189,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,6384,DB00787,10014625,63,16937,83,17165,0.135192728,0.769261971,0.545048076,1.081102363,0.262942829,DB0078710014625_,1.335818651,-0.262323703,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,6392,DB00787,10048294,70,16930,88,17160,0.201885431,0.806267628,0.580025947,1.117122787,0.35126488,DB0078710048294_,1.046214695,-0.215339547,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,acyclovir,DB00787
,6397,DB00207,10059866,11,9069,45,5410,6.68241853775727e-11,0.145838907,0.067987932,0.286709101,2.24900603412228e-09,DB0020710059866_,19.91277748,-1.925252642,male,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,6398,DB00319,10059866,17,1375,41,1812,0.043786172,0.546511634,0.289790627,0.988392344,0.113156969,DB0031910059866_,2.178979322,-0.604199683,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,piperacillin,DB00319
,6400,DB00787,10059866,18,16982,35,17213,0.027101543,0.521293849,0.277820204,0.946127907,0.078238777,DB0078710059866_,2.547989881,-0.651441387,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,6414,DB00425,10069327,55,12640,24,7460,0.243861649,1.352498944,0.822494531,2.286676726,0.402290988,DB0042510069327_,0.910579602,0.301953951,NA,10069327,Product quality issue,10077536,Product issues,Prod,zolpidem,DB00425
,6416,DB00203,10043607,102,13776,63,8875,0.810845446,1.043051321,0.753631772,1.453202934,0.898226748,DB0020310043607_,0.107332739,0.04215038,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,sildenafil,DB00203
,6417,DB00374,10043607,89,17627,32,5692,0.596484856,0.89809509,0.592771704,1.392242455,0.741883949,DB0037410043607_,0.298562451,-0.107479326,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,treprostinil,DB00374
,6418,DB00374,10020751,113,17603,21,5703,0.019848789,1.743206716,1.086232094,2.928149707,0.061379461,DB0037410020751_,2.790680006,0.555726357,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,treprostinil,DB00374
,6420,DB00374,10040880,43,17673,13,5711,1,1.06886667,0.563698282,2.168241838,1,DB0037410040880_,0,0.066598901,NA,10040880,Skin irritation,10040785,Skin and subcutaneous tissue disorders,Skin,treprostinil,DB00374
,6421,DB00811,10022437,139,2659,205,3951,0.955071604,1.007510602,0.801780612,1.263101581,0.992902767,DB0081110022437_,0.007122538,0.007482538,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ribavirin,DB00811
,6422,DB08934,10022437,228,4261,273,5931,0.104715638,1.162467918,0.966340059,1.397413434,0.218059065,DB0893410022437_,1.522989315,0.15054526,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,sofosbuvir,DB08934
,6423,DB00820,10038687,72,11843,38,5778,0.684845211,0.924416102,0.614807839,1.409723595,0.809622937,DB0082010038687_,0.21118665,-0.078592982,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,6424,DB00108,10012174,65,10129,25,3270,0.460826742,0.839356712,0.520894853,1.392235585,0.628177411,DB0010810012174_,0.464932651,-0.175119499,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,natalizumab,DB00108
,6426,DB00108,10028813,204,9990,36,3259,0.000456641,1.848645208,1.288911249,2.719284453,0.002863264,DB0010810028813_,5.855793074,0.614453051,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,natalizumab,DB00108
,6428,DB00108,10047700,138,10056,38,3257,0.426861754,1.176201382,0.814171929,1.735735478,0.59554465,DB0010810047700_,0.518278914,0.162290078,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,natalizumab,DB00108
,6429,DB08931,10013573,962,5615,290,2156,0.000689865,1.273731529,1.105211187,1.470934326,0.004043506,DB0893110013573_,5.510643265,0.241950804,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,6433,DB08908,10041466,50,10623,18,3261,0.56688232,0.852689478,0.488081347,1.555420798,0.71815789,DB0890810041466_,0.331065832,-0.159359832,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,6435,DB00005,10033295,72,128010,39,42380,0.015425765,0.611204542,0.408330512,0.927247611,0.050393517,DB0000510033295_,2.987892734,-0.49232361,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,6437,DB00005,10000059,836,127246,198,42221,1.23261894553657e-05,1.400931667,1.198020787,1.644738087,0.000130362,DB0000510000059_,8.945197567,0.337137492,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,6438,DB00175,10000059,98,8033,70,6036,0.814112305,1.051965787,0.764723595,1.453531559,0.90030679,DB0017510000059_,0.105019696,0.050660592,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,6439,DB00264,10000059,327,29280,222,24670,0.014060034,1.241054162,1.042473276,1.479685302,0.046754127,DB0026410000059_,3.062852743,0.215961149,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,6440,DB00316,10000059,681,64793,311,36642,0.001781613,1.238371423,1.080598515,1.421584301,0.008843301,DB0031610000059_,4.72809503,0.213797148,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,6441,DB00381,10000059,427,28933,227,22660,2.22740121223339e-06,1.473209728,1.249984439,1.739965199,2.91497340620137e-05,DB0038110000059_,10.44306477,0.387443509,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,6443,DB00557,10000059,60,5927,21,3046,0.156559305,1.46828273,0.878304162,2.546525553,0.292810682,DB0055710000059_,1.228229015,0.384093507,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,hydroxyzine,DB00557
,6444,DB00727,10000059,37,3806,35,4138,0.556621897,1.149336952,0.70260113,1.883514272,0.709940392,DB0072710000059_,0.342574267,0.139185213,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,nitroglycerin,DB00727
,6445,DB00829,10000059,83,7969,32,4422,0.095804527,1.43923277,0.944871891,2.240951577,0.204484123,DB0082910000059_,1.587264943,0.364110173,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,diazepam,DB00829
,6446,DB00973,10000059,62,3789,44,2977,0.623566694,1.107137393,0.737857497,1.673445712,0.763571804,DB0097310000059_,0.269748113,0.101777759,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ezetimibe,DB00973
,6448,DB00005,10013710,36,128046,20,42399,0.06459001,0.596024083,0.33586025,1.086784732,0.151733704,DB0000510013710_,1.885628245,-0.517474205,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,6449,DB00175,10013710,40,8091,77,6029,7.07939617679992e-07,0.387114599,0.256997359,0.575324898,1.05518530483236e-05,DB0017510013710_,11.45920907,-0.949034508,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,6450,DB00264,10013710,287,29320,324,24568,0.000272652,0.742246839,0.630419988,0.873574925,0.001865589,DB0026410013710_,6.284178355,-0.298073423,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,6451,DB00316,10013710,322,65152,215,36738,0.058436131,0.844519894,0.708054047,1.008855151,0.140575088,DB0031610013710_,1.962013501,-0.168986986,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,6452,DB00381,10013710,190,29170,240,22647,5.77541204949243e-07,0.614650411,0.505019587,0.747240144,8.80804790953922e-06,DB0038110013710_,11.63984472,-0.48670161,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,6454,DB00557,10013710,67,5920,55,3012,0.011924899,0.619807545,0.426187123,0.904746235,0.040951917,DB0055710013710_,3.19535666,-0.47834626,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,6455,DB00727,10013710,40,3803,48,4125,0.66884924,0.903918115,0.57750496,1.408031172,0.798874778,DB0072710013710_,0.224551069,-0.101016504,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,6456,DB00829,10013710,79,7973,81,4373,0.000117331,0.534943073,0.386484706,0.740233855,0.000915014,DB0082910013710_,6.996571701,-0.625594943,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,6457,DB00973,10013710,20,3831,57,2964,9.33939599793002e-08,0.271518843,0.154157261,0.460083481,1.7000417161052e-06,DB0097310013710_,13.28485777,-1.30372374,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,6460,DB00264,10022052,88,29519,32,24860,2.08783617407848e-05,2.315869844,1.528748388,3.589381806,0.000207207,DB0026410022052_,8.481792266,0.839785359,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,6461,DB00316,10022052,188,65286,44,36909,1.4232557897549e-08,2.415535521,1.731270373,3.436103231,3.08665663644451e-07,DB0031610022052_,14.99100714,0.88192101,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,6462,DB00381,10022052,69,29291,25,22862,0.000782231,2.15415655,1.345160785,3.554531076,0.004490266,DB0038110022052_,5.405843298,0.767399255,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,6469,DB00005,10061364,41,128041,17,42402,0.447951588,0.798674281,0.443821665,1.49955501,0.615714324,DB0000510061364_,0.484972183,-0.224802074,NA,10061364,Skin injury,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,6479,DB00005,10064265,201,127881,94,42325,0.006904712,0.707718005,0.551127513,0.914286694,0.026515882,DB0000510064265_,3.630011417,-0.345709563,NA,10064265,Skin haemorrhage,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,6495,DB00571,10025482,138,4985,39,2570,0.000697039,1.824114167,1.265786964,2.682877107,0.004076919,DB0057110025482_,5.502413697,0.601094481,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,6496,DB00811,10025482,63,2735,75,4081,0.18985131,1.253342653,0.87888484,1.782529691,0.336326315,DB0081110025482_,1.089673416,0.225814105,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,6503,DB00571,10037087,85,5038,24,2585,0.010382874,1.817104621,1.140442968,2.997956215,0.036681486,DB0057110037087_,3.30548311,0.597244367,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,propranolol,DB00571
,6504,DB00811,10037087,103,2695,130,4026,0.221388424,1.183575233,0.900595609,1.552258978,0.375226149,DB0081110037087_,0.98022637,0.168539716,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ribavirin,DB00811
,6512,DB00811,10069327,25,2773,35,4121,0.894950833,1.061496749,0.607539888,1.829401032,0.955976233,DB0081110069327_,0.045022227,0.05967994,NA,10069327,Product quality issue,10077536,Product issues,Prod,ribavirin,DB00811
,6519,DB00559,10039710,66,9593,7,3299,0.001056142,3.242386417,1.486696726,8.385944911,0.005764862,DB0055910039710_,5.155974123,1.176309607,female,10039710,Scleroderma,10028395,Musculoskeletal and connective tissue disorders,Musc,bosentan,DB00559
,6520,DB00108,10011906,494,9700,280,3015,6.04303357019902e-14,0.548433522,0.469919876,0.640973278,3.18958107214219e-12,DB0010810011906_,26.47113153,-0.600689207,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,6527,DB00338,10009802,32,33642,26,22246,0.502488403,0.813864504,0.469772777,1.422281454,0.663697278,DB0033810009802_,0.40992914,-0.205961384,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,omeprazole,DB00338
,6544,DB00126,10017955,82,10089,77,5868,0.002884802,0.619439226,0.447440487,0.858172893,0.013092054,DB0012610017955_,4.335749774,-0.478940684,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,6545,DB00169,10017955,175,38516,160,18015,2.06087245272464e-09,0.511564537,0.410186354,0.638418824,5.37134679423571e-08,DB0016910017955_,16.73960207,-0.670281529,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,6546,DB00175,10017955,95,8036,95,6011,0.054760042,0.748032623,0.555747126,1.006848529,0.133932046,DB0017510017955_,2.010422731,-0.290308688,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,6548,DB00207,10017955,27,9053,30,5425,0.020063715,0.539370474,0.30815365,0.939809903,0.061920248,DB0020710017955_,2.78190804,-0.617352609,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,6549,DB00264,10017955,380,29227,392,24500,0.004512555,0.81261098,0.703086253,0.939143256,0.018813606,DB0026410017955_,3.973174945,-0.207502783,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,6550,DB00316,10017955,405,65069,315,36638,2.13023619755705e-05,0.723965921,0.622914154,0.841933413,0.000210751,DB0031610017955_,8.464832023,-0.323010958,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,6552,DB00338,10017955,254,33420,256,22016,2.11678179251411e-06,0.653644199,0.546811721,0.781257237,2.78755558197561e-05,DB0033810017955_,10.48776039,-0.425192113,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,6553,DB00404,10017955,100,19792,72,9790,0.018219624,0.686995979,0.501891996,0.944432993,0.057389711,DB0040410017955_,2.857890236,-0.37542684,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,6557,DB00646,10017955,32,3421,18,1982,1,1.02997411,0.559280152,1.954332135,1,DB0064610017955_,0,0.029533666,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,nystatin,DB00646
,6559,DB00864,10017955,38,6831,37,8355,0.35271329,1.256132202,0.776545426,2.033536921,0.52247563,DB0086410017955_,0.649176937,0.228037319,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,6561,DB01015,10017955,38,9849,66,9315,0.002999312,0.544561888,0.355018282,0.824705507,0.013507569,DB0101510017955_,4.304505063,-0.607773683,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,6562,DB01104,10017955,80,15383,66,7220,0.000929128,0.568912258,0.405026421,0.801513272,0.005184046,DB0110410017955_,5.262169377,-0.564029061,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,6565,DB01306,10017955,39,4169,44,3822,0.377692847,0.812611654,0.512992303,1.282923971,0.54770382,DB0130610017955_,0.602020613,-0.207501954,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,insulin aspart,DB01306
,6566,DB01592,10017955,81,6195,53,3014,0.096150143,0.743548413,0.517997997,1.075120854,0.204972141,DB0159210017955_,1.584881205,-0.296321401,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,6568,DB11089,10017955,99,10076,101,8306,0.134355022,0.808024348,0.605204876,1.078641576,0.261777824,DB1108910017955_,1.340259133,-0.213163087,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,6569,DB00126,10037377,68,10103,45,5900,0.557369091,0.882476591,0.595849392,1.318107565,0.710479695,DB0012610037377_,0.34181491,-0.125023016,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,6570,DB00175,10037377,44,8087,50,6056,0.046941586,0.65902463,0.428658299,1.00998254,0.119346095,DB0017510037377_,2.125727647,-0.416994371,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,6572,DB00207,10037377,53,9027,42,5413,0.201845809,0.75672678,0.494504477,1.164533541,0.351238558,DB0020710037377_,1.046289635,-0.278753015,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,6573,DB00316,10037377,481,64993,313,36640,0.049372439,0.866349101,0.749392704,1.002681636,0.12384336,DB0031610037377_,2.088737737,-0.143467333,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,6575,DB00338,10037377,238,33436,221,22051,0.000320036,0.710249417,0.588442335,0.857547848,0.002127231,DB0033810037377_,6.15293404,-0.34213908,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,6576,DB00404,10037377,107,19785,66,9796,0.168677431,0.802724202,0.584607832,1.109202362,0.309091401,DB0040410037377_,1.174118251,-0.219744084,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,6582,DB00864,10037377,20,6849,36,8356,0.179483796,0.677813776,0.371416168,1.203915053,0.323225358,DB0086410037377_,1.129405497,-0.388882696,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tacrolimus,DB00864
,6584,DB01015,10037377,73,9814,89,9292,0.114788901,0.776610356,0.561204208,1.071855592,0.233323765,DB0101510037377_,1.455328239,-0.252816526,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,6586,DB01233,10037377,42,3379,16,1710,0.401823267,1.328382502,0.728781992,2.538845673,0.571594576,DB0123310037377_,0.559325323,0.283962038,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoclopramide,DB01233
,6588,DB01592,10037377,32,6244,20,3047,0.378119049,0.780828049,0.432251379,1.443079068,0.548124043,DB0159210037377_,0.601253662,-0.247400321,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iron,DB01592
,6590,DB11089,10037377,119,10056,106,8301,0.590169712,0.926724264,0.706056758,1.217694429,0.73676613,DB1108910037377_,0.305484764,-0.076099208,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,6591,DB00126,10053762,266,9905,127,5818,0.063832489,1.230208591,0.989531211,1.535978278,0.150370763,DB0012610053762_,1.894651281,0.207183741,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ascorbic acid,DB00126
,6592,DB00169,10053762,2744,35947,554,17621,1.32365060960371e-91,2.427928305,2.211170839,2.669518435,2.30756558880655e-88,DB0016910053762_,201.7912951,0.887038344,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,6593,DB00175,10053762,226,7905,135,5971,0.035560514,1.264481614,1.014367321,1.581110366,0.096605665,DB0017510053762_,2.3371179,0.234662247,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,6595,DB00207,10053762,259,8821,218,5237,0.000209792,0.70539548,0.584836829,0.851360285,0.001499897,DB0020710053762_,6.502358518,-0.348996669,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,azithromycin,DB00207
,6596,DB00264,10053762,792,28815,555,24337,0.000883826,1.205254623,1.078479058,1.347673992,0.00497726,DB0026410053762_,5.302875692,0.18669085,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,6598,DB00404,10053762,496,19396,191,9671,0.002403383,1.294841334,1.091529839,1.54090481,0.011304095,DB0040410053762_,4.482590256,0.258388166,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,6600,DB00582,10053762,65,1065,94,1480,0.868443998,0.960951765,0.682485563,1.346358271,0.941341079,DB0058210053762_,0.060449741,-0.039831063,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,voriconazole,DB00582
,6602,DB00646,10053762,88,3365,50,1950,1,1.019907868,0.709329635,1.480346886,1,DB0064610053762_,0,0.019712298,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,nystatin,DB00646
,6603,DB00681,10053762,33,380,74,568,0.075340475,0.666818967,0.419526372,1.041309971,0.170394457,DB0068110053762_,1.769639195,-0.405236684,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,amphotericin b,DB00681
,6604,DB00993,10053762,170,3079,124,1495,0.001094229,0.665711262,0.520560234,0.853225678,0.005930883,DB0099310053762_,5.127582257,-0.406899244,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,azathioprine,DB00993
,6605,DB01015,10053762,214,9673,247,9134,0.033882547,0.818129703,0.676482201,0.988761153,0.093148132,DB0101510053762_,2.373564234,-0.200734394,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sulfamethoxazole,DB01015
,6606,DB01104,10053762,414,15049,242,7044,0.007449093,0.800780122,0.679882769,0.944758624,0.028142209,DB0110410053762_,3.570484734,-0.222168874,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,6607,DB01216,10053762,21,215,162,6953,3.38256057702229e-07,4.190601648,2.474994432,6.785311516,5.4462851312117e-06,DB0121610053762_,12.12057681,1.432844315,female,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,finasteride,DB01216
,6608,DB01233,10053762,120,3301,51,1675,0.323274,1.193868723,0.848619444,1.700196756,0.491710959,DB0123310053762_,0.709864217,0.177199061,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,metoclopramide,DB01233
,6609,DB01306,10053762,104,4104,98,3768,0.886663067,0.974337607,0.729487551,1.302168749,0.952901543,DB0130610053762_,0.048243693,-0.025997416,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin aspart,DB01306
,6610,DB01592,10053762,155,6121,69,2998,0.564622556,1.100236556,0.820351311,1.48826841,0.716402216,DB0159210053762_,0.333513516,0.095525207,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,iron,DB01592
,6611,DB01610,10053762,115,826,137,1081,0.499520838,1.098508803,0.835583381,1.442343149,0.661322919,DB0161010053762_,0.413513027,0.093953626,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,valganciclovir,DB01610
,6614,DB00641,10013968,690,13434,471,12004,9.66148482299222e-06,1.309011674,1.159543195,1.478714139,0.000105484,DB0064110013968_,9.156953644,0.269272405,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,6615,DB00641,10019303,65,14059,26,12449,0.000457174,2.213569077,1.383970078,3.637837184,0.002866264,DB0064110019303_,5.85474591,0.79460618,NA,10019303,Heart rate increased,10022891,Investigations,Inv,simvastatin,DB00641
,6616,DB00641,10031009,35,14089,26,12449,0.523484833,1.189449116,0.695363063,2.058891884,0.681717293,DB0064110031009_,0.383140234,0.173490272,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,6617,DB00641,10069327,68,14056,56,12419,0.719052881,1.072889157,0.741525078,1.557862218,0.83410717,DB0064110069327_,0.181393383,0.070355156,NA,10069327,Product quality issue,10077536,Product issues,Prod,simvastatin,DB00641
,6619,DB00555,10069326,93,6954,59,3427,0.139994848,0.776846385,0.553084946,1.0984415,0.269842069,DB0055510069326_,1.309918419,-0.252512651,NA,10069326,Product substitution issue,10077536,Product issues,Prod,lamotrigine,DB00555
,6620,DB01590,10028034,46,4692,29,2838,0.904843276,0.959463042,0.588494698,1.587677786,0.957667115,DB0159010028034_,0.043255041,-0.041381482,NA,10028034,Mouth ulceration,10017947,Gastrointestinal disorders,Gastr,everolimus,DB01590
,6621,DB00153,10037844,224,7199,89,3350,0.218238663,1.171168906,0.908855339,1.519896714,0.371418855,DB0015310037844_,0.990424864,0.158002315,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ergocalciferol,DB00153
,6622,DB00254,10037844,267,5668,107,3281,0.001436283,1.444400039,1.144951456,1.832605634,0.007419217,DB0025410037844_,4.903681737,0.367694038,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,doxycycline,DB00254
,6623,DB00264,10037844,695,28912,536,24356,0.132397422,1.092348663,0.973226558,1.226490592,0.259116656,DB0026410037844_,1.35047691,0.088330115,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,6624,DB00635,10037844,1005,32048,468,23326,8.01186837894973e-16,1.562987915,1.397375094,1.750288717,5.41367507302554e-14,DB0063510037844_,30.54726313,0.446599319,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,6625,DB00641,10037844,353,13771,271,12204,0.080971671,1.154355503,0.980641922,1.360003552,0.180001724,DB0064110037844_,1.714788852,0.143542182,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,6626,DB00722,10037844,640,24763,589,25443,0.056746147,1.116422534,0.995261769,1.252501062,0.137345531,DB0072210037844_,1.985255406,0.110129407,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,6627,DB00814,10037844,247,8040,79,3336,0.047961942,1.297234836,0.999588776,1.698830693,0.121271671,DB0081410037844_,2.109722036,0.26023495,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,meloxicam,DB00814
,6628,DB00924,10037844,288,9874,96,4155,0.053681126,1.262359059,0.995640864,1.612189695,0.13188736,DB0092410037844_,2.025807054,0.23298224,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cyclobenzaprine,DB00924
,6629,DB01373,10037844,632,22088,159,7222,0.003339073,1.299607941,1.088167931,1.559572485,0.014748365,DB0137310037844_,4.216623033,0.262062635,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,6630,DB00153,10042682,54,7369,8,3431,0.000893562,3.142489883,1.484250211,7.654272265,0.005021866,DB0015310042682_,5.293953623,1.145015442,female,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,6632,DB00264,10042682,118,29489,56,24836,0.000322173,1.774638851,1.280011538,2.486025058,0.002138731,DB0026410042682_,6.147542408,0.573596938,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,6633,DB00635,10042682,187,32866,63,23731,5.05769983823885e-08,2.143193386,1.601970643,2.9005227,9.76793829890581e-07,DB0063510042682_,13.83899023,0.762296953,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,6634,DB00641,10042682,89,14035,26,12449,9.07446710827204e-08,3.035961859,1.94103631,4.90092103,1.65640533292313e-06,DB0064110042682_,13.31086077,1.110528297,female,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,6635,DB00722,10042682,157,25246,143,25889,0.324986476,1.125861759,0.891241456,1.423172319,0.493432825,DB0072210042682_,0.706368549,0.11854875,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,6636,DB00814,10042682,46,8241,9,3406,0.037105779,2.112306065,1.020108925,4.914114093,0.099808166,DB0081410042682_,2.304505278,0.747780273,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,6638,DB01373,10042682,118,22602,16,7365,0.000384906,2.403256922,1.418766047,4.344527808,0.002484285,DB0137310042682_,5.997770586,0.876824868,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,6639,DB06643,10042682,124,52297,14,7501,0.442411678,1.270382069,0.728771173,2.39274591,0.610467266,DB0664310042682_,0.493530605,0.239317697,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,6642,DB00264,10043528,35,29572,21,24871,0.230098281,1.401708877,0.79334713,2.534921329,0.386067491,DB0026410043528_,0.951743078,0.337692118,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,6643,DB00635,10043528,74,32979,23,23771,0.00026852,2.319017172,1.435154523,3.882167937,0.001843316,DB0063510043528_,6.296189213,0.841143463,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,6645,DB00722,10043528,36,25367,26,26006,0.20361694,1.419477501,0.833343177,2.449061355,0.353411997,DB0072210043528_,1.040120773,0.350288847,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,6650,DB00005,10037844,2728,125354,693,41726,1.19838915809321e-10,1.310308374,1.204177145,1.427354592,3.84846170073061e-09,DB0000510037844_,19.37559233,0.270262509,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,6651,DB13961,10037844,293,9164,163,6251,0.041919614,1.226131818,1.006138193,1.498414762,0.109539422,DB1396110037844_,2.211470776,0.20386435,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,fish oil,DB13961
,6652,DB00722,10002198,85,25318,135,25897,0.001454761,0.644037451,0.484778797,0.851579556,0.00749961,DB0072210002198_,4.892904263,-0.4399984,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,lisinopril,DB00722
,6654,DB00722,10007515,149,25254,233,25799,4.72133104406366e-05,0.653294223,0.527865225,0.806458655,0.000420821,DB0072210007515_,7.7733024,-0.42572768,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,lisinopril,DB00722
,6655,DB01164,10007515,142,6382,237,7699,0.002396633,0.722816266,0.581315147,0.896174417,0.011276382,DB0116410007515_,4.485044788,-0.324600216,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,calcium chloride,DB01164
,6656,DB00722,10013887,62,25341,79,25953,0.206551903,0.803768615,0.566605626,1.135744795,0.357126575,DB0072210013887_,1.029665007,-0.218443843,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,6658,DB00722,10033425,614,24789,365,25667,3.19918902802237e-17,1.741741216,1.525795559,1.99061565,2.54050403630115e-15,DB0072210033425_,33.60641389,0.554885312,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,6659,DB01164,10033425,34,6490,31,7905,0.262068768,1.335864306,0.795733943,2.250394309,0.423788956,DB0116410033425_,0.858519694,0.289578502,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium chloride,DB01164
,6660,DB00087,10011906,22,1347,46,701,4.23928178015165e-08,0.249069423,0.141459507,0.426470499,8.30943486885058e-07,DB0008710011906_,14.00070405,-1.390023615,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,alemtuzumab,DB00087
,6661,DB00788,10013946,66,9290,38,5023,0.757867459,0.93909614,0.619737632,1.441215406,0.86477594,DB0078810013946_,0.145284834,-0.062837419,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,6662,DB08908,10013946,83,10590,18,3261,0.196005653,1.419855666,0.843989668,2.51612684,0.344259034,DB0890810013946_,1.066360898,0.350555223,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,6663,DB00788,10061818,60,9296,49,5012,0.034266468,0.660185516,0.444391032,0.985039699,0.093929932,DB0078810061818_,2.365206176,-0.415234398,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,6666,DB00005,10060891,85,127997,26,42393,0.826185988,1.082778353,0.690679301,1.751149603,0.908265772,DB0000510060891_,0.096218242,0.079530287,NA,10060891,General symptom,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,6667,DB00005,10064355,535,127547,222,42197,0.00538482,0.797278083,0.68025881,0.936978352,0.021701931,DB0000510064355_,3.830354039,-0.226551749,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,6685,DB00480,10013710,46,67382,29,67633,0.050017661,1.592100694,0.978998026,2.62857963,0.125026652,DB0048010013710_,2.079228346,0.465054335,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,6695,DB01268,10025482,103,2040,138,2992,0.5026397,1.094665902,0.834357081,1.432555476,0.663781198,DB0126810025482_,0.409802704,0.090449205,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,6699,DB00722,10011224,623,24780,483,25549,3.20012228582394e-06,1.329870586,1.177383632,1.502692694,4.00834950120955e-05,DB0072210011224_,10.1245459,0.285081634,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,6700,DB00722,10047924,96,25307,118,25914,0.19333194,0.833076914,0.629232826,1.100626116,0.340837174,DB0072210047924_,1.076350412,-0.182629307,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,6701,DB00363,10011906,414,4214,662,6226,0.239790577,0.923956819,0.810149661,1.052917962,0.397621381,DB0036310011906_,0.92225503,-0.079089941,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,clozapine,DB00363
,6702,DB00203,10010305,131,13747,84,8854,1,1.004438915,0.756918232,1.339047099,1,DB0020310010305_,0,0.004429093,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,sildenafil,DB00203
,6703,DB00374,10010305,132,17584,36,5688,0.417290775,1.186066257,0.81395169,1.768037462,0.5864404,DB0037410010305_,0.533684235,0.170642165,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,treprostinil,DB00374
,6704,DB08932,10010305,195,19248,57,6540,0.344466353,1.162380351,0.859997275,1.592423799,0.513821076,DB0893210010305_,0.665880176,0.150469929,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,macitentan,DB08932
,6705,DB00203,10013573,1027,12851,385,8553,4.01135498745779e-22,1.7753305,1.572422784,2.007473518,5.15591520026054e-20,DB0020310013573_,44.41155722,0.573986603,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,6706,DB08932,10013573,1584,17859,436,6161,4.55419976701311e-05,1.253290779,1.121989294,1.402147798,0.000407861,DB0893210013573_,7.804584651,0.225772715,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,6707,DB00203,10016334,68,13810,40,8898,0.693339585,1.095348845,0.72983879,1.663218598,0.815319583,DB0020310016334_,0.204175116,0.091072892,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,6708,DB00374,10016334,89,17627,24,5700,0.510087064,1.199141529,0.756038568,1.970795838,0.670606515,DB0037410016334_,0.399572729,0.181605909,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,6709,DB08932,10016334,96,19347,27,6570,0.46677164,1.207408238,0.780051111,1.927323129,0.633390596,DB0893210016334_,0.456667991,0.18847611,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,6713,DB00203,10037660,502,13376,211,8727,6.87442171232817e-08,1.552213829,1.315944804,1.83604126,1.28929129296144e-06,DB0020310037660_,13.56141788,0.439682188,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,6714,DB00374,10037660,538,17178,154,5570,0.192676977,1.132768464,0.942745267,1.367501544,0.340002977,DB0037410037660_,1.078800907,0.124664604,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,6715,DB08932,10037660,679,18764,169,6428,0.000185772,1.376316181,1.158347288,1.642688583,0.001355262,DB0893210037660_,6.603760247,0.319410496,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,6716,DB00203,10040047,250,13628,126,8812,0.025156054,1.282937793,1.029725824,1.604997494,0.07384297,DB0020310040047_,2.605814467,0.249152599,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,sildenafil,DB00203
,6717,DB08932,10040047,361,19082,128,6469,0.67460567,0.956114487,0.77781123,1.181475154,0.802680279,DB0893210040047_,0.219798803,-0.044877617,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,macitentan,DB08932
,6718,DB00203,10048294,54,13824,36,8902,0.913957923,0.965907897,0.621440221,1.51748089,0.961512267,DB0020310048294_,0.039247956,-0.034686794,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,sildenafil,DB00203
,6719,DB00374,10048294,67,17649,30,5694,0.154409255,0.72053919,0.461375763,1.149552969,0.290027673,DB0037410048294_,1.237778937,-0.327755473,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,treprostinil,DB00374
,6720,DB08932,10048294,103,19340,29,6568,0.422534357,1.206176506,0.791354962,1.891457469,0.591524426,DB0893210048294_,0.525052302,0.187455444,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,macitentan,DB08932
,6724,DB00203,10064687,246,13632,85,8853,2.12954302613123e-07,1.879467523,1.460769119,2.438058608,3.58814348986278e-06,DB0020310064687_,12.53787562,0.630988504,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,6725,DB00374,10064687,390,17326,115,5609,0.402445296,1.097872464,0.887453864,1.366767973,0.572262624,DB0037410064687_,0.558157259,0.093374183,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,6726,DB08932,10064687,218,19225,44,6553,0.001003306,1.688685162,1.215150433,2.394193339,0.005518865,DB0893210064687_,5.19958308,0.523950216,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,6727,DB00005,10057880,143,127939,23,42396,0.000610881,2.060164331,1.32021083,3.354839976,0.003653888,DB0000510057880_,5.611963527,0.722785752,NA,10057880,Injection site nodule,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,6728,DB06703,10046735,255,520,105,306,0.009608788,1.428692925,1.085477574,1.887846025,0.034484844,DB0670310046735_,3.367235354,0.356759988,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,gadobutrol,DB06703
,6729,DB00005,10021789,1934,126148,574,41845,0.019972279,1.117652995,1.016982969,1.229761488,0.06169601,DB0000510021789_,2.785536018,0.111230947,NA,10021789,Infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,6732,DB00559,10007559,255,9404,105,3201,0.110798603,0.826640893,0.653647857,1.051572671,0.227278076,DB0055910007559_,1.481581006,-0.190384906,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,bosentan,DB00559
,6733,DB00682,10007559,436,19023,293,16071,0.002646388,1.257128065,1.079934025,1.464942009,0.012202494,DB0068210007559_,4.406114951,0.228829806,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,warfarin,DB00682
,6742,DB00451,10021654,67,47204,19,15400,0.706958204,1.15043317,0.682562141,2.028868547,0.824750993,DB0045110021654_,0.192673765,0.140138541,NA,10021654,Increased appetite,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,6747,DB00331,10029883,44,24902,29,20723,0.348674586,1.262613568,0.772203365,2.093402104,0.518170934,DB0033110029883_,0.657450103,0.233183833,NA,10029883,Obesity,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,6748,DB00451,10029883,53,47218,26,15393,0.089880639,0.664540605,0.408053873,1.107498793,0.195031378,DB0045110029883_,1.634594822,-0.408659296,NA,10029883,Obesity,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,6753,DB00331,10049040,36,24910,30,20722,1,0.9982497,0.597539904,1.678559508,1,DB0033110049040_,0,-0.001751833,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,6754,DB00451,10049040,59,47212,18,15401,0.894993494,1.06923705,0.621684669,1.927013495,0.955976233,DB0045110049040_,0.045022227,0.066945356,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,6766,DB06404,10042674,55,3014,17,883,0.887005234,0.947839561,0.538639524,1.751281717,0.953020806,DB0640410042674_,0.048118544,-0.053570031,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,human c1-esterase inhibitor,DB06404
,6767,DB06404,10048959,55,3014,27,873,0.03219652,0.590113974,0.363368904,0.979284259,0.089520868,DB0640410048959_,2.41328352,-0.527439585,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,human c1-esterase inhibitor,DB06404
,6769,DB00051,10044755,48,25683,28,11392,0.263125903,0.760375241,0.467241675,1.25935347,0.424923704,DB0005110044755_,0.855845647,-0.273943229,NA,10044755,Tuberculosis,10021881,Infections and infestations,Infec,adalimumab,DB00051
,6772,DB00005,10043882,129,127953,55,42364,0.124362663,0.776558631,0.562085015,1.085342913,0.247623104,DB0000510043882_,1.395847429,-0.252883132,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,etanercept,DB00005
,6773,DB01273,10013700,351,1689,158,1117,0.000165877,1.469006903,1.195317532,1.810967955,0.001230443,DB0127310013700_,6.700381377,0.384586597,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,varenicline,DB01273
,6774,DB00230,10030124,185,19489,73,8578,0.455642911,1.115430251,0.845234952,1.48517991,0.623017344,DB0023010030124_,0.473180921,0.109240206,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,6775,DB00441,10007882,32,2242,25,1869,0.893684515,1.067049696,0.610244916,1.885340045,0.955733567,DB0044110007882_,0.0452761,0.064897547,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,gemcitabine,DB00441
,6776,DB00441,10015150,44,2230,20,1874,0.022700814,1.84852546,1.062471179,3.323025456,0.068212735,DB0044110015150_,2.685124,0.614388273,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,gemcitabine,DB00441
,6777,DB00441,10033425,45,2229,19,1875,0.011187147,1.991931288,1.137127075,3.619683854,0.038937255,DB0044110033425_,3.245803781,0.689104664,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,gemcitabine,DB00441
,6779,DB00051,10013968,495,25236,223,11197,0.870248823,0.984876026,0.837802282,1.16064552,0.94234532,DB0005110013968_,0.05938349,-0.015239508,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,6780,DB00051,10016256,963,24768,372,11048,0.02003972,1.154704624,1.021213284,1.3077594,0.06185709,DB0005110016256_,2.782928549,0.143844575,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,6781,DB00051,10028813,1032,24699,266,11154,3.53560206971511e-17,1.752037417,1.52671293,2.016199828,2.78660570921924e-15,DB0005110028813_,33.51395213,0.560779349,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,6782,DB00051,10029410,64,25667,36,11384,0.277651958,0.788527508,0.515896647,1.222101517,0.441278333,DB0005110029410_,0.818079461,-0.237587987,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,6783,DB00051,10037660,299,25432,180,11240,0.001398946,0.734140592,0.607354887,0.889473002,0.007254152,DB0005110037660_,4.926181266,-0.309054727,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,6784,DB00230,10033371,2430,17244,744,7907,5.14902626897559e-21,1.49761827,1.372992721,1.634859948,6.00186942261745e-19,DB0023010033371_,41.95704578,0.403876026,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,6785,DB00230,10053762,823,18851,304,8347,0.008257242,1.198706847,1.046948051,1.375279133,0.030544504,DB0023010053762_,3.488570516,0.181243348,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,6786,DB00983,10003239,67,3434,21,1719,0.067522506,1.596965333,0.961947724,2.755356011,0.156904838,DB0098310003239_,1.852115785,0.468105161,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,formoterol,DB00983
,6787,DB09072,10003239,79,6392,32,2503,0.915443483,0.966723345,0.63176159,1.510963163,0.962143444,DB0907210003239_,0.03859173,-0.03384292,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium oxybate,DB09072
,6788,DB00983,10003549,53,3448,24,1716,0.807540474,1.09901999,0.664035628,1.868327153,0.896111849,DB0098310003549_,0.109690043,0.094418865,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,formoterol,DB00983
,6789,DB09072,10003549,79,6392,33,2502,0.751673215,0.937054554,0.615048872,1.4566171,0.859798101,DB0907210003549_,0.151057684,-0.065013776,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,6792,DB00983,10003988,46,3455,18,1722,0.425319233,1.273702415,0.721759118,2.341356792,0.594102087,DB0098310003988_,0.52070411,0.241927947,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,formoterol,DB00983
,6793,DB09072,10003988,105,6366,60,2475,0.022746964,0.680403709,0.489033667,0.9540167,0.068296755,DB0907210003988_,2.683893023,-0.385068968,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium oxybate,DB09072
,6794,DB00983,10006451,65,3436,20,1720,0.062856869,1.626753631,0.968973846,2.845372954,0.148698838,DB0098310006451_,1.905832237,0.486586392,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,formoterol,DB00983
,6795,DB09072,10006451,74,6397,19,2516,0.104938732,1.531823447,0.913168596,2.691923489,0.218437107,DB0907210006451_,1.521257144,0.426458821,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,sodium oxybate,DB09072
,6800,DB00983,10010264,44,3457,17,1723,0.414314426,1.289984305,0.719767788,2.415604662,0.583599297,DB0098310010264_,0.538540666,0.254630052,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,formoterol,DB00983
,6801,DB09072,10010264,342,6129,137,2398,0.834602442,0.976710691,0.794125653,1.206514053,0.91418995,DB0907210010264_,0.089716907,-0.023564791,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,6804,DB00983,10012378,48,3453,13,1727,0.054833639,1.846496411,0.981434071,3.725346505,0.134052488,DB0098310012378_,2.009523852,0.613290012,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,formoterol,DB00983
,6805,DB09072,10012378,378,6093,169,2366,0.141355,0.868564177,0.717914795,1.05412933,0.271760983,DB0907210012378_,1.302832337,-0.140913802,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,6806,DB00983,10013573,83,3418,31,1709,0.191232872,1.338658378,0.872380336,2.101758145,0.33814706,DB0098310013573_,1.08427439,0.291667902,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,formoterol,DB00983
,6807,DB00983,10013968,470,3031,210,1530,0.176135892,1.129754666,0.946786633,1.351188228,0.318878817,DB0098310013968_,1.142944132,0.122000499,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,formoterol,DB00983
,6808,DB09072,10013968,155,6316,55,2480,0.586831704,1.106554987,0.805510062,1.539448289,0.733958477,DB0907210013968_,0.309302823,0.101251574,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium oxybate,DB09072
,6813,DB00983,10022437,61,3440,7,1733,2.15134056668358e-05,4.388698235,2.000601951,11.39980588,0.000212586,DB0098310022437_,8.456161986,1.479032653,female,10022437,Insomnia,10037175,Psychiatric disorders,Psych,formoterol,DB00983
,6814,DB09072,10022437,329,6142,135,2400,0.633717111,0.952280325,0.772556803,1.178960409,0.772217685,DB0907210022437_,0.258488794,-0.048895828,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,6817,DB00983,10033425,53,3448,14,1726,0.035953194,1.894848677,1.032872742,3.708834354,0.097425022,DB0098310033425_,2.328672198,0.639138981,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,formoterol,DB00983
,6818,DB09072,10033425,71,6400,18,2517,0.09839148,1.551257933,0.912448964,2.771472424,0.208473664,DB0907210033425_,1.567942557,0.439066171,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium oxybate,DB09072
,6820,DB09072,10036018,54,6417,19,2516,0.794039352,1.114327449,0.648497258,1.994889194,0.888406094,DB0907210036018_,0.118326328,0.108251038,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,sodium oxybate,DB09072
,6824,DB09072,10041349,456,6015,196,2339,0.258651964,0.904712955,0.75821308,1.082494936,0.419709656,DB0907210041349_,0.868192101,-0.100137563,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,6825,DB00983,10044565,41,3460,14,1726,0.251120274,1.460801524,0.7775509,2.909668993,0.41102786,DB0098310044565_,0.889094281,0.378985274,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,formoterol,DB00983
,6826,DB09072,10044565,199,6272,43,2492,0.00020396,1.838658567,1.311956712,2.628647493,0.001464575,DB0907210044565_,6.526190109,0.609036266,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,6829,DB00112,10010305,76,5857,78,4013,0.013180369,0.667638147,0.478982028,0.930177068,0.044376329,DB0011210010305_,3.115049082,-0.404008948,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,bevacizumab,DB00112
,6831,DB00112,10012174,161,5772,103,3988,0.568356184,1.079992288,0.835234704,1.401543834,0.719391438,DB0011210012174_,0.329349649,0.0769539,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,bevacizumab,DB00112
,6835,DB00112,10033425,106,5827,57,4034,0.127826146,1.287392559,0.921975497,1.813751778,0.252586847,DB0011210033425_,1.376000141,0.2526189,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,bevacizumab,DB00112
,6836,DB01254,10033425,51,3416,37,3111,0.333800688,1.255264208,0.803645102,1.977416559,0.502877265,DB0125410033425_,0.687409144,0.227346075,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,dasatinib,DB01254
,6837,DB00112,10035664,71,5862,69,4022,0.046110788,0.70604027,0.498410251,1.000618417,0.117706329,DB0011210035664_,2.139562491,-0.348083003,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,bevacizumab,DB00112
,6838,DB01254,10035664,83,3384,63,3085,0.314689789,1.201019243,0.851854409,1.700349038,0.482288341,DB0125410035664_,0.729213125,0.183170565,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,dasatinib,DB01254
,6839,DB01254,10037660,60,3407,82,3066,0.017120529,0.658519566,0.462230969,0.933577099,0.054682922,DB0125410037660_,2.906203824,-0.417761045,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,dasatinib,DB01254
,6842,DB00112,10040047,69,5864,52,4039,0.642421615,0.913965914,0.626967618,1.339368164,0.778894908,DB0011210040047_,0.249879148,-0.089962002,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,bevacizumab,DB00112
,6847,DB00316,10002544,118,65356,26,36927,3.14470678219482e-06,2.564265898,1.665622781,4.087235989,3.94457732140257e-05,DB0031610002544_,10.14058366,0.941672238,NA,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,6849,DB01373,10002544,61,22659,10,7371,0.038736004,1.984191986,1.008283677,4.34654562,0.103106416,DB0137310002544_,2.271993656,0.685211771,NA,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,6850,DB00783,10016256,849,15865,13,360,0.187900564,1.481930463,0.850876028,2.822510011,0.333950866,DB0078310016256_,1.096761405,0.393345604,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,estradiol,DB00783
,6851,DB00783,10037377,564,16150,8,365,0.242367211,1.593326574,0.794548068,3.737090278,0.400579882,DB0078310037377_,0.914842078,0.465824016,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,estradiol,DB00783
,6852,DB01373,10037377,130,22590,68,7313,0.002059432,0.618901781,0.457513885,0.84359733,0.009961753,DB0137310037377_,4.609002225,-0.479808692,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,6853,DB00316,10047899,886,64588,325,36628,7.13934428601644e-12,1.546001235,1.359017109,1.762196547,2.79668650607962e-10,DB0031610047899_,21.9974156,0.435671749,NA,10047899,Weight increased,10022891,Investigations,Inv,acetaminophen,DB00316
,6854,DB01373,10047899,358,22362,75,7306,0.000310647,1.559448362,1.210982286,2.030839138,0.002076908,DB0137310047899_,6.17687506,0.444332145,NA,10047899,Weight increased,10022891,Investigations,Inv,calcium,DB01373
,6855,DB00316,10051055,428,65046,346,36607,8.06679684334859e-07,0.696193593,0.602394631,0.804957859,1.1862140141394e-05,DB0031610051055_,11.34215873,-0.362127507,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,6856,DB01373,10051055,131,22589,101,7280,2.59120820327039e-10,0.418020322,0.319524672,0.54814615,7.93359436493444e-09,DB0137310051055_,18.65215964,-0.872225231,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,calcium,DB01373
,6857,DB00374,10020919,651,17065,214,5510,0.808973859,0.982228654,0.837748672,1.155174044,0.896971703,DB0037410020919_,0.108730963,-0.017931153,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,treprostinil,DB00374
,6858,DB00682,10020919,367,19092,145,16219,6.48227524449292e-16,2.150060002,1.767184722,2.627494021,4.40845031827934e-14,DB0068210020919_,30.75266808,0.765495749,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,6861,DB00374,10039163,469,17247,163,5561,0.424933396,0.927732047,0.772555552,1.11854955,0.593689335,DB0037410039163_,0.521399102,-0.07501233,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,treprostinil,DB00374
,6862,DB00682,10039163,214,19245,87,16277,3.1394673084152e-09,2.080334001,1.612638081,2.70334254,7.90260354492587e-08,DB0068210039163_,16.35348848,0.732528458,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,warfarin,DB00682
,6863,DB00374,10046571,283,17433,37,5687,8.56105635392818e-09,2.495210846,1.76438316,3.621626458,1.95421073610944e-07,DB0037410046571_,15.44810925,0.914373233,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,6864,DB00682,10061818,259,19200,141,16223,2.6296742933321e-05,1.552044686,1.257955982,1.921302351,0.000252312,DB0068210061818_,8.284842457,0.439573214,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,6878,DB00338,10051398,99,33575,191,22081,4.12915750892103e-19,0.340888479,0.2644789,0.437033343,3.96112792416019e-17,DB0033810051398_,37.76741777,-1.076199897,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,omeprazole,DB00338
,6879,DB00904,10051398,237,22832,226,14230,7.31816903617307e-06,0.653613139,0.54171352,0.788746521,8.24686272736588e-05,DB0090410051398_,9.403092612,-0.425239633,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ondansetron,DB00904
,6890,DB06643,10002855,192,52229,33,7482,0.314284188,0.833481822,0.573322085,1.246438698,0.481927479,DB0664310002855_,0.729961635,-0.182143387,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,denosumab,DB06643
,6895,DB00051,10042945,109,25622,17,11403,1.02244909132057e-05,2.853434734,1.701712876,5.079521603,0.000110711,DB0005110042945_,9.108588133,1.048523439,female,10042945,Systemic lupus erythematosus,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,6899,DB00046,10005555,152,5307,106,4586,0.100091598,1.239119273,0.957402533,1.608536864,0.210915423,DB0004610005555_,1.556298067,0.214400864,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,insulin lispro,DB00046
,6900,DB00047,10005555,209,9076,198,8320,0.76339489,0.967623527,0.791011809,1.184063967,0.869021853,DB0004710005555_,0.140387007,-0.032912186,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,insulin glargine,DB00047
,6901,DB00046,10005557,724,4735,603,4089,0.554848631,1.036861041,0.921908627,1.166404271,0.708324581,DB0004610005557_,0.344852843,0.036197919,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,insulin lispro,DB00046
,6902,DB00047,10005557,869,8416,743,7775,0.14322367,1.080466828,0.973818133,1.199087136,0.274340256,DB0004710005557_,1.293386132,0.077393195,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,insulin glargine,DB00047
,6903,DB00864,10021789,52,6817,86,8306,0.085962637,0.736737399,0.511000476,1.053247982,0.18827046,DB0086410021789_,1.669875734,-0.30552376,NA,10021789,Infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,6904,DB01254,10016256,281,3186,275,2873,0.374950174,0.921448653,0.771458853,1.100601278,0.544762199,DB0125410016256_,0.607405912,-0.081808224,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dasatinib,DB01254
,6907,DB00572,10013709,135,2767,126,2000,0.046154768,0.774481296,0.598743098,1.002349631,0.117807154,DB0057210013709_,2.138706276,-0.255561769,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,atropine,DB00572
,6909,DB00091,10013774,118,5392,18,2652,2.51625725406765e-07,3.223923486,1.948670659,5.640151116,4.17460468939353e-06,DB0009110013774_,12.38649089,1.170599092,female,10013774,Dry eye,10015919,Eye disorders,Eye,cyclosporine,DB00091
,6910,DB00193,10013774,58,19262,13,8689,0.020350757,2.012536188,1.089130147,4.006032524,0.062655302,DB0019310013774_,2.770106978,0.699395712,NA,10013774,Dry eye,10015919,Eye disorders,Eye,tramadol,DB00193
,6911,DB00381,10013774,77,29283,28,22859,0.000354303,2.146656596,1.376085729,3.438248083,0.002316633,DB0038110013774_,6.067640649,0.76391156,NA,10013774,Dry eye,10015919,Eye disorders,Eye,amlodipine,DB00381
,6912,DB00563,10013774,165,46481,11,15337,1.94041479563457e-10,4.949439254,2.69404414,10.11233512,6.04668676979901e-09,DB0056310013774_,18.92375536,1.599274288,female,10013774,Dry eye,10015919,Eye disorders,Eye,methotrexate,DB00563
,6913,DB00722,10013774,55,25348,31,26001,0.006931789,1.819866023,1.150859996,2.925385433,0.026594961,DB0072210013774_,3.627033505,0.598762885,NA,10013774,Dry eye,10015919,Eye disorders,Eye,lisinopril,DB00722
,6915,DB00005,10014551,78,128004,11,42408,0.004624991,2.349348444,1.243216546,4.898791015,0.019209588,DB0000510014551_,3.95234573,0.854138032,NA,10014551,Emotional disorder,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,6922,DB00005,10027951,70,128012,15,42404,0.133058405,1.545787461,0.876224307,2.908061112,0.26002306,DB0000510027951_,1.34698496,0.435533464,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,6927,DB00722,10027951,38,25365,20,26012,0.01735109,1.948427225,1.10530065,3.535260813,0.055291677,DB0072210027951_,2.89513288,0.667022496,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,6929,DB00005,10047513,409,127673,131,42288,0.765025729,1.034135257,0.847093155,1.269206672,0.870359749,DB0000510047513_,0.138848648,0.033565577,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,etanercept,DB00005
,6930,DB00091,10047513,165,5345,27,2643,4.74458570639278e-09,3.021500421,1.996832272,4.736088198,1.145718284727e-07,DB0009110047513_,15.98206389,1.105753536,female,10047513,Vision blurred,10015919,Eye disorders,Eye,cyclosporine,DB00091
,6931,DB00193,10047513,131,19189,61,8641,0.814849731,0.96705945,0.707620804,1.334322415,0.900608932,DB0019310047513_,0.104684153,-0.033495307,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,tramadol,DB00193
,6932,DB00563,10047513,132,46514,51,15297,0.3452761,0.851219562,0.611429107,1.200897635,0.514705002,DB0056310047513_,0.664161354,-0.161085179,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,methotrexate,DB00563
,6933,DB01060,10047513,45,8542,24,5057,0.710060436,1.110037691,0.661153203,1.907212825,0.827117597,DB0106010047513_,0.189808397,0.10439397,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,amoxicillin,DB01060
,6934,DB00331,10007625,18,24928,33,20719,0.007015752,0.453361243,0.240271446,0.829181253,0.0268407,DB0033110007625_,3.617835881,-0.791066025,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,metformin,DB00331
,6937,DB00412,10007649,25,1039,36,1350,0.793903048,0.902317419,0.515686428,1.556298456,0.888291402,DB0041210007649_,0.118455435,-0.102788915,NA,10007649,Cardiovascular disorder,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,6939,DB00331,10037423,109,24837,75,20677,0.208222151,1.209905738,0.892904395,1.646889783,0.359069656,DB0033110037423_,1.024238882,0.190542454,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,6940,DB00412,10037423,95,969,101,1285,0.153375141,1.247208271,0.920539371,1.688788839,0.288693872,DB0041210037423_,1.242388419,0.22090767,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosiglitazone,DB00412
,6942,DB00060,10017577,415,9093,109,2356,0.912020087,0.986483861,0.792920885,1.235671955,0.96056931,DB0006010017577_,0.040229139,-0.013608314,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,6943,DB00060,10019465,32,9476,19,2446,0.005251626,0.434773445,0.238573725,0.813339768,0.021271128,DB0006010019465_,3.850404622,-0.832930199,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,6944,DB00415,10037844,56,730,18,524,0.003248436,2.231924585,1.274851826,4.083878914,0.014429059,DB0041510037844_,4.238511097,0.802864256,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ampicillin,DB00415
,6948,DB00654,10030124,34,3782,20,2578,0.677129556,1.158743256,0.646516638,2.129662641,0.804227119,DB0065410030124_,0.217873563,0.147336018,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,6949,DB00706,10030124,14,1061,181,15744,0.555364267,1.147744237,0.612916371,1.985036104,0.708750207,DB0070610030124_,0.344252133,0.137798483,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,6954,DB00706,10050584,10,1065,110,15815,0.34449608,1.349942729,0.627905279,2.587821763,0.513850837,DB0070610050584_,0.665822256,0.300062168,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,tamsulosin,DB00706
,6962,DB00682,10062546,58,19401,45,16319,0.693532732,1.084164958,0.721426164,1.6384778,0.815455507,DB0068210062546_,0.204008417,0.080810067,NA,10062546,Thrombosis in device,10077536,Product issues,Prod,warfarin,DB00682
,6966,DB01240,10062546,67,5684,29,1547,0.04471143,0.62884617,0.399505559,1.012391034,0.11502226,DB0124010062546_,2.162629607,-0.463868615,NA,10062546,Thrombosis in device,10077536,Product issues,Prod,epoprostenol,DB01240
,6968,DB00588,10063829,34,16490,18,8450,0.884540366,0.967897599,0.531160512,1.821596841,0.951918915,DB0058810063829_,0.049275421,-0.032628984,NA,10063829,Device malfunction,10077536,Product issues,Prod,fluticasone propionate,DB00588
,6969,DB00682,10063829,71,19388,27,16337,0.00033064,2.215716558,1.40362992,3.592768318,0.002186109,DB0068210063829_,6.125632028,0.795575854,NA,10063829,Device malfunction,10077536,Product issues,Prod,warfarin,DB00682
,6970,DB00695,10063829,47,28002,36,20492,0.825206488,0.955384081,0.605578873,1.518706765,0.90753962,DB0069510063829_,0.097018056,-0.045641841,NA,10063829,Device malfunction,10077536,Product issues,Prod,furosemide,DB00695
,6972,DB01240,10063829,124,5627,36,1540,0.770420533,0.942678335,0.642696822,1.413211457,0.874236414,DB0124010063829_,0.134404443,-0.059030163,NA,10063829,Device malfunction,10077536,Product issues,Prod,epoprostenol,DB01240
,6973,DB01080,10011906,175,1884,175,1937,0.823333164,1.028131807,0.820858823,1.287722445,0.906247631,DB0108010011906_,0.098442687,0.027743376,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,vigabatrin,DB01080
,6974,DB00559,10020772,91,9568,23,3283,0.234571747,1.357520833,0.849919871,2.252161787,0.391449575,DB0055910020772_,0.937898573,0.305660119,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,bosentan,DB00559
,6975,DB00682,10020772,190,19269,117,16247,0.00804548,1.369232515,1.08074591,1.740754564,0.029924359,DB0068210020772_,3.50908245,0.314250375,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,warfarin,DB00682
,6976,DB00559,10033371,266,9393,75,3231,0.147403357,1.219954231,0.937702289,1.603193906,0.280323933,DB0055910033371_,1.271809441,0.198813342,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,6977,DB00682,10033371,733,18726,316,16048,1.77520037094172e-25,1.987849306,1.736819895,2.27936852,2.8194043353597e-23,DB0068210033371_,51.9229315,0.687053304,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,6978,DB00559,10033557,200,9459,25,3281,1.07182898742682e-07,2.7749478,1.821644078,4.399355895,1.93230623693511e-06,DB0055910033557_,13.15679633,1.020631936,female,10033557,Palpitations,10007541,Cardiac disorders,Card,bosentan,DB00559
,6979,DB00682,10033557,423,19036,88,16276,1.98432819491343e-42,4.109633623,3.256167781,5.236709401,8.48098643956087e-40,DB0068210033557_,89.96557695,1.413333882,female,10033557,Palpitations,10007541,Cardiac disorders,Card,warfarin,DB00682
,6981,DB00196,10013968,189,4894,89,3196,0.012385948,1.386749383,1.067776664,1.812101033,0.042212596,DB0019610013968_,3.165036628,0.326962435,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluconazole,DB00196
,6982,DB00588,10013968,1313,15211,615,7853,0.056978876,1.102227382,0.996867242,1.21970275,0.13774393,DB0058810013968_,1.982358897,0.097333025,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,6983,DB00196,10022000,54,5029,24,3261,0.131057711,1.458924415,0.884524197,2.472946765,0.257308929,DB0019610022000_,1.357477857,0.377699462,NA,10022000,Influenza,10021881,Infections and infestations,Infec,fluconazole,DB00196
,6984,DB00588,10022000,249,16275,100,8368,0.040217136,1.280293652,1.009552943,1.633705144,0.106087351,DB0058810022000_,2.243492458,0.247089467,NA,10022000,Influenza,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,6986,DB00588,10062237,47,16477,30,8438,0.337722991,0.802327193,0.496523893,1.314893269,0.506838187,DB0058810062237_,0.679563485,-0.220238783,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,fluticasone propionate,DB00588
,6988,DB08908,10046735,174,10499,24,3255,6.45983747286797e-05,2.247471348,1.458670642,3.609693126,0.000548351,DB0890810046735_,7.508595314,0.809805739,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,dimethyl fumarate,DB08908
,6989,DB08875,10051398,75,568,183,1060,0.077021738,0.764940548,0.565663108,1.026809034,0.173208378,DB0887510051398_,1.753259915,-0.267957163,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cabozantinib,DB08875
,6990,DB00158,10002855,237,16578,59,8045,1.79277426531248e-06,1.949305564,1.458120538,2.642263617,2.4036251754011e-05,DB0015810002855_,10.63594738,0.667473188,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,folic acid,DB00158
,6991,DB00341,10002855,258,11147,70,4998,0.000134569,1.652524632,1.261453954,2.188852592,0.001026747,DB0034110002855_,6.88135972,0.502304198,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,cetirizine,DB00341
,6992,DB00451,10002855,857,46414,160,15259,5.3325325684196e-12,1.760808013,1.484162317,2.100190486,2.14320517677231e-10,DB0045110002855_,22.26354848,0.565772802,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,6993,DB00563,10002855,315,46331,64,15284,0.000260131,1.623593801,1.23674415,2.160368783,0.001794921,DB0056310002855_,6.322793996,0.484642088,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,6994,DB01076,10002855,320,25427,214,25369,5.74057890825422e-06,1.49189675,1.249737879,1.783821801,6.6706948100558e-05,DB0107610002855_,9.615201441,0.400048297,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,6995,DB01373,10002855,323,22397,75,7306,0.008195881,1.404813292,1.088010337,1.833619138,0.030395586,DB0137310002855_,3.493457862,0.339904406,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,calcium,DB01373
,6996,DB00158,10003239,724,16091,232,7872,1.62004972278553e-08,1.526671935,1.311684419,1.782054756,3.4648500377069e-07,DB0015810003239_,14.8754263,0.423090161,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,6997,DB00341,10003239,337,11068,100,4968,0.000230107,1.512628466,1.203373708,1.915224516,0.001620456,DB0034110003239_,6.425047791,0.413848843,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,6998,DB01076,10003239,718,25029,429,25154,1.20283990139924e-17,1.681989959,1.488385845,1.902542206,9.97370561775367e-16,DB0107610003239_,34.5414093,0.519977592,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,6999,DB01373,10003239,905,21815,131,7250,5.40425842789874e-22,2.29595522,1.905582425,2.78448518,6.89567634841352e-20,DB0137310003239_,44.12080726,0.831148975,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,7007,DB00005,10005750,386,127696,96,42323,0.011257865,1.332629345,1.062827284,1.684851717,0.039126321,DB0000510005750_,3.24095988,0.287153942,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,etanercept,DB00005
,7008,DB00158,10005750,128,16687,57,8047,0.637559103,1.082901012,0.785701668,1.508601789,0.774804246,DB0015810005750_,0.255144868,0.079643562,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,folic acid,DB00158
,7009,DB00341,10005750,111,11294,53,5015,0.67112271,0.929978835,0.663360855,1.317927352,0.800438343,DB0034110005750_,0.222595773,-0.072593451,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,cetirizine,DB00341
,7010,DB00563,10005750,196,46450,34,15314,0.000298294,1.900434254,1.314756084,2.823419454,0.002008518,DB0056310005750_,6.210358126,0.642082415,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,methotrexate,DB00563
,7011,DB01076,10005750,225,25522,198,25385,0.222267269,1.130260424,0.928845711,1.376253429,0.376363793,DB0107610005750_,0.977199068,0.12244807,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,atorvastatin,DB01076
,7012,DB01373,10005750,179,22541,53,7328,0.592227631,1.097963368,0.802997476,1.523226422,0.738465935,DB0137310005750_,0.303180305,0.09345698,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,calcium,DB01373
,7013,DB00005,10010741,107,127975,15,42404,0.000748176,2.363716649,1.370550373,4.370698835,0.004325009,DB0000510010741_,5.443341093,0.860235232,NA,10010741,Conjunctivitis,10021881,Infections and infestations,Infec,etanercept,DB00005
,7017,DB00563,10010741,42,46604,9,15339,0.329065864,1.535912254,0.736745711,3.589551818,0.497669519,DB0056310010741_,0.697819039,0.429124507,NA,10010741,Conjunctivitis,10021881,Infections and infestations,Infec,methotrexate,DB00563
,7020,DB00005,10011878,76,128006,44,42375,0.004142462,0.571797566,0.389329182,0.848966099,0.01757621,DB0000510011878_,4.041209014,-0.558970257,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,etanercept,DB00005
,7023,DB00451,10011878,89,47182,29,15390,1,1.001046571,0.651528392,1.579968819,1,DB0045110011878_,0,0.001046023,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,levothyroxine,DB00451
,7024,DB00563,10011878,39,46607,19,15329,0.170504993,0.675113642,0.380701397,1.237292526,0.311512041,DB0056310011878_,1.166317285,-0.392874244,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,methotrexate,DB00563
,7025,DB01076,10011878,42,25705,30,25553,0.194356086,1.391706981,0.850289033,2.303489457,0.342173458,DB0107610011878_,1.072437483,0.330531038,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,atorvastatin,DB01076
,7026,DB01373,10011878,45,22675,7,7374,0.074803401,2.090432803,0.935296304,5.497284105,0.169515251,DB0137310011878_,1.774812378,0.737371127,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,calcium,DB01373
,7030,DB00451,10013554,49,47222,11,15408,0.296269874,1.453431156,0.745389457,3.100691437,0.462122283,DB0045110013554_,0.771925741,0.373927075,NA,10013554,Diverticulum,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,7034,DB00005,10015958,198,127884,40,42379,0.003348554,1.640299071,1.162788327,2.366072261,0.014780309,DB0000510015958_,4.214459426,0.494878585,NA,10015958,Eye pain,10015919,Eye disorders,Eye,etanercept,DB00005
,7037,DB00451,10015958,143,47128,25,15394,0.002927975,1.868286147,1.215104444,2.984654744,0.013246442,DB0045110015958_,4.324026325,0.625021512,NA,10015958,Eye pain,10015919,Eye disorders,Eye,levothyroxine,DB00451
,7038,DB00563,10015958,52,46594,13,15335,0.471952731,1.316459578,0.706624652,2.636263069,0.638049507,DB0056310015958_,0.449339402,0.274945995,NA,10015958,Eye pain,10015919,Eye disorders,Eye,methotrexate,DB00563
,7039,DB01076,10015958,75,25672,28,25555,3.98649265986508e-06,2.666468578,1.705881679,4.277403117,4.84554726310075e-05,DB0107610015958_,9.934865272,0.980754967,NA,10015958,Eye pain,10015919,Eye disorders,Eye,atorvastatin,DB01076
,7040,DB01373,10015958,55,22665,7,7374,0.016934276,2.556357651,1.160296232,6.657969861,0.054239105,DB0137310015958_,2.914353134,0.938583453,NA,10015958,Eye pain,10015919,Eye disorders,Eye,calcium,DB01373
,7041,DB00341,10016256,807,10598,342,4726,0.466002996,1.052245251,0.921689163,1.203216893,0.632788591,DB0034110016256_,0.457618893,0.050926215,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,7042,DB00158,10016825,72,16743,18,8086,0.01262023,1.931747254,1.139220641,3.443810805,0.042863774,DB0015810016825_,3.149728229,0.658424906,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,folic acid,DB00158
,7043,DB00341,10016825,111,11294,34,5034,0.057713699,1.455149778,0.981467287,2.207745384,0.139174731,DB0034110016825_,1.972025079,0.375108836,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,cetirizine,DB00341
,7044,DB00451,10016825,309,46962,45,15374,3.92099731604437e-08,2.248076984,1.639281737,3.14760764,7.73749357749447e-07,DB0045110016825_,14.07201784,0.810075177,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,7045,DB00563,10016825,83,46563,27,15321,1,1.011489229,0.648011191,1.625447216,1,DB0056310016825_,0,0.011423729,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,methotrexate,DB00563
,7046,DB01076,10016825,117,25630,72,25511,0.001297017,1.617430675,1.195132282,2.201728323,0.006814332,DB0107610016825_,4.988727304,0.480838887,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,atorvastatin,DB01076
,7047,DB01373,10016825,110,22610,23,7358,0.054769169,1.556346202,0.985372152,2.559123695,0.133948138,DB0137310016825_,2.010302582,0.442340896,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,calcium,DB01373
,7055,DB00158,10019211,883,15932,207,7897,2.81685059103187e-24,2.114318727,1.810707305,2.477695271,4.11338432140404e-22,DB0015810019211_,49.24262592,0.748732646,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,7056,DB00341,10019211,762,10643,201,4867,1.83071425855408e-12,1.73357641,1.476367661,2.042828978,7.88211700017918e-11,DB0034110019211_,23.2638395,0.550186564,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,7057,DB00563,10019211,1607,45039,405,14943,6.75186495633745e-07,1.316441589,1.177862611,1.4740048,1.01239458287125e-05,DB0056310019211_,11.50060707,0.27493233,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,7058,DB01076,10019211,1044,24703,553,25030,1.46198061664595e-35,1.91283741,1.721170388,2.127619477,4.68636103762669e-33,DB0107610019211_,74.44065169,0.648587695,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,7065,DB00005,10021114,67,128015,9,42410,0.00745254,2.466378996,1.224405596,5.627144145,0.028149161,DB0000510021114_,3.570237712,0.902751081,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,etanercept,DB00005
,7066,DB00158,10021114,41,16774,10,8094,0.051795917,1.978335608,0.973937812,4.431231175,0.128414985,DB0015810021114_,2.052488191,0.682255889,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,folic acid,DB00158
,7069,DB01076,10021114,57,25690,19,25564,1.47379487269004e-05,2.985416689,1.748932794,5.315757979,0.000152646,DB0107610021114_,8.787387364,1.093739331,female,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,atorvastatin,DB01076
,7070,DB01373,10021114,77,22643,8,7373,0.000573658,3.134111517,1.512541365,7.52123933,0.003461277,DB0137310021114_,5.666117643,1.142345726,female,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,calcium,DB01373
,7071,DB00158,10022061,387,16428,39,8065,1.57995525009519e-30,4.871904108,3.495178055,6.963589358,3.64290559199579e-28,DB0015810022061_,63.179601,1.583484848,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,7072,DB00341,10022061,113,11292,21,5047,7.02239160063926e-05,2.404930755,1.498140604,4.04060932,0.000588314,DB0034110022061_,7.438249491,0.877521111,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,7073,DB00451,10022061,342,46929,27,15392,7.16332054564724e-18,4.154507671,2.803949546,6.399585248,6.08361488020477e-16,DB0045110022061_,35.03576242,1.424193931,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,7074,DB01076,10022061,141,25606,43,25540,2.16104509670923e-13,3.270847996,2.308493785,4.718014696,1.06173963302808e-11,DB0107610022061_,25.2685273,1.185049277,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,7075,DB01373,10022061,164,22556,13,7368,3.69875178706031e-09,4.120827968,2.341987305,7.909636015,9.12023365130208e-08,DB0137310022061_,16.21018532,1.416054106,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,7081,DB00158,10022095,225,16590,30,8074,1.54165117032394e-14,3.649787866,2.483823123,5.540689452,8.85586064245791e-13,DB0015810022095_,27.75252675,1.294669047,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,7082,DB00341,10022095,84,11321,18,5050,0.00347055,2.081598203,1.238847692,3.685364708,0.015221659,DB0034110022095_,4.185035927,0.733135965,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,7083,DB00451,10022095,233,47038,20,15399,7.43971095864821e-12,3.813947007,2.412233267,6.362228872,2.90568800220012e-10,DB0045110022095_,21.95918073,1.338664613,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,7084,DB01076,10022095,73,25674,40,25543,0.002443053,1.815656531,1.217887837,2.741939416,0.011453786,DB0107610022095_,4.469434961,0.596447127,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,7085,DB01373,10022095,120,22600,8,7373,7.9679046563341e-08,4.893498658,2.403597605,11.60001404,1.47282963355655e-06,DB0137310022095_,13.42832509,1.58790752,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,7086,DB00158,10022112,76,16739,8,8096,1.01615333702242e-06,4.595069372,2.215891586,11.03442135,1.45160817737144e-05,DB0015810022112_,11.14025344,1.524983853,female,10022112,Injection site warmth,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,7091,DB00158,10028411,153,16662,63,8041,0.307743347,1.171996126,0.867390824,1.599780625,0.474917592,DB0015810028411_,0.744613982,0.158708386,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,7092,DB00341,10028411,151,11254,60,5008,0.499564994,1.119898482,0.823483478,1.539738336,0.661364722,DB0034110028411_,0.413449818,0.11323804,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,7093,DB00451,10028411,672,46599,140,15279,4.24024907298056e-07,1.573773331,1.308699251,1.903693633,6.65999085051054e-06,DB0045110028411_,11.91939245,0.453476132,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,7094,DB01076,10028411,645,25102,538,25045,0.002440212,1.196156555,1.063685538,1.345507772,0.011443004,DB0107610028411_,4.47037677,0.179113546,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,7095,DB01373,10028411,365,22355,64,7317,1.35946798290489e-06,1.866758512,1.425882348,2.477742355,1.88667454755306e-05,DB0137310028411_,10.87810968,0.624203511,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,7101,DB01076,10028653,25,25722,33,25550,0.295918217,0.752516611,0.428872536,1.305012852,0.461765581,DB0107610028653_,0.772697916,-0.284332208,NA,10028653,Myositis,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,7103,DB00005,10031161,565,127517,116,42303,9.53962066982053e-07,1.61576132,1.320590579,1.991248468,1.37396673592456e-05,DB0000510031161_,11.19522348,0.479806251,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,7104,DB00158,10031161,154,16661,26,8078,3.69502711341627e-08,2.871673497,1.884791795,4.539170615,7.3245692063459e-07,DB0015810031161_,14.12686131,1.05489496,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,7105,DB00341,10031161,50,11355,13,5055,0.099812199,1.712174509,0.915302409,3.438908858,0.210491307,DB0034110031161_,1.558310926,0.537764205,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,7106,DB00451,10031161,208,47063,27,15392,6.31108450662554e-07,2.519598397,1.681676114,3.916589536,9.52939002793795e-06,DB0045110031161_,11.56112985,0.924099523,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,7107,DB00563,10031161,277,46369,57,15291,0.000912842,1.6024906,1.200501876,2.171780307,0.005112731,DB0056310031161_,5.276021528,0.471559044,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,7108,DB01076,10031161,106,25641,44,25539,4.32079757868733e-07,2.399609016,1.672558914,3.494173615,6.77840431845995e-06,DB0107610031161_,11.90176883,0.875305814,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,7109,DB01373,10031161,209,22511,12,7369,6.11970083853471e-14,5.701234685,3.192690193,11.22075953,3.22680715227452e-12,DB0137310031161_,26.45952797,1.740682763,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,7110,DB00158,10037153,320,16495,125,7979,0.046369968,1.238285751,1.002150636,1.53786859,0.118221285,DB0015810037153_,2.135197113,0.213727964,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,7111,DB00341,10037153,137,11268,39,5029,0.013521022,1.567761328,1.089495202,2.302529733,0.045276778,DB0034110037153_,3.094960995,0.449648696,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,cetirizine,DB00341
,7112,DB00563,10037153,677,45969,290,15058,0.000197759,0.764706844,0.664582055,0.881620563,0.001427459,DB0056310037153_,6.551859229,-0.26826273,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,7113,DB01076,10037153,333,25414,279,25304,0.034513973,1.188376863,1.009554196,1.399732762,0.094441627,DB0107610037153_,2.359773337,0.172588396,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,7114,DB01373,10037153,172,22548,27,7354,0.000181101,2.077516309,1.377983447,3.246492958,0.001326711,DB0137310037153_,6.625052549,0.731173098,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,7115,DB00341,10037660,291,11114,179,4889,0.000664032,0.715141953,0.589736261,0.869100764,0.003926235,DB0034110037660_,5.540074428,-0.33527422,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,7116,DB00563,10037660,663,45983,449,14899,8.67415110284067e-31,0.478433276,0.423192342,0.541351643,2.03571483694792e-28,DB0056310037660_,63.76153558,-0.737238521,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,7117,DB01076,10037660,395,25352,430,25153,0.194066949,0.911406122,0.792097427,1.048444729,0.341801779,DB0107610037660_,1.073524303,-0.092766683,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,7135,DB00451,10062060,87,47184,23,15396,0.437861788,1.234243673,0.771870311,2.049115146,0.606352476,DB0045110062060_,0.500293818,0.210458372,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,7137,DB01076,10062060,53,25694,51,25532,0.921911183,1.032670401,0.689359908,1.54818132,0.965493374,DB0107610062060_,0.03511604,0.032148069,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,7138,DB01373,10062060,90,22630,7,7374,1.47419639198017e-05,4.189465482,1.950765911,10.72564128,0.000152646,DB0137310062060_,8.787387364,1.432573156,female,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,calcium,DB01373
,7139,DB08908,10047895,129,10544,54,3225,0.064796108,0.730686284,0.526488267,1.026057696,0.152102317,DB0890810047895_,1.883201846,-0.313771071,NA,10047895,Weight decreased,10022891,Investigations,Inv,dimethyl fumarate,DB08908
,7140,DB00370,10046571,127,4414,51,3612,1.19879036577973e-05,2.037538034,1.456543101,2.88703238,0.000127237,DB0037010046571_,8.969460284,0.711742233,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,mirtazapine,DB00370
,7141,DB00656,10046571,247,11766,64,6555,1.02353464064441e-08,2.150030473,1.624304099,2.88163304,2.29945367772122e-07,DB0065610046571_,15.28542409,0.765482015,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,trazodone,DB00656
,7142,DB00814,10046571,146,8141,36,3379,0.005035734,1.683230491,1.159124937,2.502210069,0.020580622,DB0081410046571_,3.883405305,0.520714858,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,meloxicam,DB00814
,7149,DB00005,10001949,182,127900,60,42359,1,1.0046052,0.746383146,1.368802499,1,DB0000510001949_,0,0.004594628,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,7150,DB00005,10041052,54,128028,25,42394,0.191953693,0.715244032,0.437432543,1.19964098,0.339113676,DB0000510041052_,1.0814199,-0.335131491,NA,10041052,Sluggishness,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,7152,DB00264,10035226,209,29398,241,24651,0.000862626,0.727197066,0.600794335,0.879588208,0.004876681,DB0026410035226_,5.323290499,-0.318557771,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metoprolol,DB00264
,7153,DB00295,10035226,89,14574,144,9458,7.66405261022342e-12,0.401109081,0.304008072,0.526773348,2.98222979807139e-10,DB0029510035226_,21.93317965,-0.913521867,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,morphine,DB00295
,7154,DB00433,10035226,142,7514,133,5887,0.158046603,0.836501653,0.653951858,1.070551955,0.294846948,DB0043310035226_,1.221298879,-0.178526782,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prochlorperazine,DB00433
,7156,DB00060,10013709,437,9071,125,2340,0.336029064,0.901838359,0.733570959,1.115050434,0.505148639,DB0006010013709_,0.682902559,-0.103319977,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,7157,DB00108,10013709,292,9902,99,3196,0.676038954,0.951987905,0.752631551,1.212467328,0.803712608,DB0010810013709_,0.218513526,-0.049202949,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,7158,DB06637,10013709,546,5616,261,1758,2.28530915918526e-07,0.654890079,0.558489771,0.769261931,3.82851187056626e-06,DB0663710013709_,12.47303438,-0.423287876,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,7159,DB08908,10013709,550,10123,176,3103,0.621197004,0.957905279,0.802900015,1.147156427,0.761528748,DB0890810013709_,0.272427355,-0.04300638,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,7160,DB00115,10003239,572,17853,194,10278,7.78355631869217e-11,1.697399186,1.437092833,2.011751494,2.58648265280435e-09,DB0011510003239_,19.77296693,0.529097189,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,7161,DB00641,10003239,351,13773,177,12298,4.19876952844803e-10,1.770634917,1.47125526,2.137093066,1.2457241123411e-08,DB0064110003239_,18.20096377,0.571338193,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,7162,DB00722,10003239,595,24808,374,25658,4.04495282915708e-14,1.645390517,1.441601534,1.879823081,2.17426554426163e-12,DB0072210003239_,26.85433019,0.497977753,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,7163,DB09270,10003239,131,2983,58,2310,0.000418662,1.748876188,1.267812623,2.437454523,0.002659705,DB0927010003239_,5.929540004,0.558973403,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ubidecarenone,DB09270
,7164,DB13961,10003239,340,9117,126,6288,1.24558910008785e-09,1.861020455,1.508585177,2.307636796,3.40335857544793e-08,DB1396110003239_,17.19591798,0.621124969,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,7165,DB00005,10008190,295,127787,172,42247,1.05521144592336e-08,0.567030003,0.468084915,0.688626079,2.36455523069869e-07,DB0000510008190_,15.25750571,-0.567343061,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,7166,DB00115,10008190,152,18273,117,10355,0.015303639,0.736234036,0.573956709,0.946284341,0.050103526,DB0011510008190_,2.993663894,-0.306207227,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,7167,DB00563,10008190,126,46520,66,15282,0.003230006,0.627149322,0.46173751,0.858563347,0.01436682,DB0056310008190_,4.242833927,-0.466570613,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,7168,DB00641,10008190,164,13960,155,12320,0.572588261,0.933788382,0.744049439,1.172304389,0.72264284,DB0064110008190_,0.324840176,-0.068505439,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,7169,DB00722,10008190,286,25117,298,25734,0.867798609,0.983305702,0.832299967,1.161536263,0.940796702,DB0072210008190_,0.061028207,-0.016835218,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,7170,DB01611,10008190,52,11861,19,2342,0.024958052,0.540435093,0.313515575,0.969838455,0.073376479,DB0161110008190_,2.61215185,-0.615380737,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,hydroxychloroquine,DB01611
,7172,DB13961,10008190,74,9383,58,6356,0.423440614,0.864274112,0.603642438,1.242578266,0.592264815,DB1396110008190_,0.523801422,-0.145865301,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,7173,DB00115,10047895,458,17967,304,10168,0.035643431,0.852624337,0.734370388,0.991004505,0.096774178,DB0011510047895_,2.335375079,-0.15943623,NA,10047895,Weight decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,7174,DB00563,10047895,386,46260,163,15185,0.008416581,0.777339611,0.645016451,0.94021972,0.031014977,DB0056310047895_,3.473285046,-0.251877944,NA,10047895,Weight decreased,10022891,Investigations,Inv,methotrexate,DB00563
,7175,DB00641,10047895,289,13835,281,12194,0.25218068,0.906484515,0.765112798,1.074089855,0.412314196,DB0064110047895_,0.885969608,-0.098181331,NA,10047895,Weight decreased,10022891,Investigations,Inv,simvastatin,DB00641
,7176,DB01611,10047895,168,11745,33,2328,1,1.00907908,0.689423038,1.517700975,1,DB0161110047895_,0,0.009038113,NA,10047895,Weight decreased,10022891,Investigations,Inv,hydroxychloroquine,DB01611
,7177,DB09270,10047895,72,3042,64,2304,0.381097213,0.852098769,0.597207078,1.218081097,0.551118882,DB0927010047895_,0.595804736,-0.160052833,NA,10047895,Weight decreased,10022891,Investigations,Inv,ubidecarenone,DB09270
,7178,DB13961,10047895,235,9222,181,6233,0.205604504,0.877538397,0.71780849,1.0741935,0.35596805,DB1396110047895_,1.0329143,-0.130634567,NA,10047895,Weight decreased,10022891,Investigations,Inv,fish oil,DB13961
,7179,DB00005,10048706,339,127743,121,42298,0.482758174,0.927670496,0.751413046,1.151707276,0.647050054,DB0000510048706_,0.435331624,-0.075078678,NA,10048706,Joint range of motion decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,7181,DB00563,10048706,196,46450,56,15292,0.38046067,1.15224489,0.851683782,1.580752795,0.550501415,DB0056310048706_,0.596925753,0.141712117,NA,10048706,Joint range of motion decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,7187,DB00005,10061428,465,127617,124,42295,0.031635377,1.242820968,1.017063274,1.528097152,0.088296882,DB0000510061428_,2.427050481,0.21738377,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,etanercept,DB00005
,7188,DB00115,10061428,358,18067,198,10274,0.789301818,1.028185484,0.860402569,1.231509988,0.885851185,DB0011510061428_,0.121206306,0.027795583,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,cyanocobalamin,DB00115
,7189,DB00563,10061428,233,46413,112,15236,0.001375342,0.682923904,0.542401124,0.864058732,0.007159297,DB0056310061428_,4.939343493,-0.38137184,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,7190,DB00641,10061428,230,13894,257,12218,0.008993683,0.786997433,0.654717813,0.94552524,0.032710523,DB0064110061428_,3.42005845,-0.239530292,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,simvastatin,DB00641
,7191,DB01611,10061428,114,11799,17,2344,0.343654855,1.332170186,0.794606014,2.371058942,0.512901675,DB0161110061428_,0.667671118,0.286809331,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,hydroxychloroquine,DB01611
,7192,DB09270,10061428,60,3054,58,2310,0.189752431,0.782508881,0.533936263,1.147556331,0.336196464,DB0927010061428_,1.090059575,-0.245250007,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ubidecarenone,DB09270
,7193,DB00005,10061762,98,127984,34,42385,0.840365687,0.954557776,0.640136119,1.454958641,0.918366576,DB0000510061762_,0.085158648,-0.046507107,NA,10061762,Chondropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,7201,DB08865,10011906,86,1125,110,861,0.000679002,0.598506911,0.439668398,0.812635539,0.00399194,DB0886510011906_,5.523478039,-0.513317207,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,crizotinib,DB08865
,7206,DB06643,10019303,65,52356,11,7504,0.602032876,0.846937228,0.443249884,1.780547227,0.74618919,DB0664310019303_,0.292776105,-0.166128698,NA,10019303,Heart rate increased,10022891,Investigations,Inv,denosumab,DB06643
,7213,DB00028,10011224,226,13232,121,5494,0.027760768,0.775497199,0.617685779,0.977557994,0.07969682,DB0002810011224_,2.529525591,-0.254250909,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human immunoglobulin g,DB00028
,7214,DB00028,10047924,60,13398,27,5588,0.724880553,0.926844365,0.578657141,1.520320475,0.838634345,DB0002810047924_,0.17598049,-0.075969618,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human immunoglobulin g,DB00028
,7215,DB00028,10051792,334,13124,147,5468,0.577672398,0.946658037,0.775342532,1.160348443,0.726599784,DB0002810051792_,0.319379456,-0.054817352,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,human immunoglobulin g,DB00028
,7216,DB00005,10061623,916,127166,217,42202,5.1372168716455e-06,1.400842139,1.206390854,1.632539727,6.06747901465747e-05,DB0000510061623_,9.709982265,0.337073584,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,7217,DB01590,10011906,323,4415,278,2589,9.02392959589128e-06,0.68139335,0.574296602,0.808783313,9.93274662596325e-05,DB0159010011906_,9.217088426,-0.383615533,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,7219,DB00153,10013573,275,7148,102,3337,0.055218402,1.258581398,0.995306529,1.601730878,0.134712157,DB0015310013573_,2.004614947,0.229985212,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,7220,DB00335,10013573,317,8149,192,5273,0.488240066,1.068350354,0.887117677,1.28917659,0.651821628,DB0033510013573_,0.427984331,0.066115733,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,7221,DB14512,10013573,121,4723,50,2362,0.285865541,1.210197298,0.860151351,1.724698576,0.450536477,DB1451210013573_,0.797316236,0.190783402,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,mometasone furoate,DB14512
,7222,DB00153,10016322,149,7274,40,3399,0.001537975,1.74054109,1.217271035,2.539697405,0.00785375,DB0015310016322_,4.846764211,0.554196036,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,7223,DB00316,10016322,949,64525,345,36608,4.26142434045929e-13,1.560605612,1.377266486,1.771636319,2.00199354403883e-11,DB0031610016322_,24.63429257,0.445073959,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,7224,DB00335,10016322,175,8291,53,5412,3.30391592693707e-07,2.155210222,1.573403901,2.994882658,5.32781779997184e-06,DB0033510016322_,12.14256882,0.76788827,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,7225,DB00641,10016322,227,13897,131,12344,7.70303227189858e-05,1.539150346,1.234140032,1.926053622,0.000637212,DB0064110016322_,7.358407702,0.431230541,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,7226,DB06643,10016322,418,52003,43,7472,0.040210621,1.396734681,1.017866924,1.961142006,0.106080408,DB0664310016322_,2.243557908,0.334137142,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,7227,DB14512,10016322,75,4769,28,2384,0.206950229,1.338977753,0.854293634,2.153366778,0.357591821,DB1451210016322_,1.028363108,0.291906452,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,7228,DB00153,10019211,436,6987,114,3325,6.03424206238593e-09,1.819956303,1.471138753,2.266318599,1.42634939397315e-07,DB0015310019211_,15.76297734,0.598812491,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,7229,DB00335,10019211,411,8055,132,5333,8.90559254068639e-14,2.061346071,1.684842401,2.535340718,4.60341199472845e-12,DB0033510019211_,26.10422335,0.723359202,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,7230,DB06643,10019211,553,51868,65,7450,0.142468671,1.22197804,0.942547444,1.607361397,0.27325251,DB0664310019211_,1.297358965,0.20047089,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,7231,DB14512,10019211,256,4588,76,2336,2.81728042949897e-05,1.714929317,1.315731016,2.256842182,0.000268695,DB1451210019211_,8.221935351,0.539371865,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,mometasone furoate,DB14512
,7232,DB00153,10020642,70,7353,33,3406,0.915627185,0.98257283,0.639348234,1.537930739,0.962215366,DB0015310020642_,0.03851698,-0.01758081,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,ergocalciferol,DB00153
,7233,DB00316,10020642,533,64941,300,36653,1,1.002758848,0.868298632,1.159677321,1,DB0031610020642_,0,0.00275505,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,7234,DB00335,10020642,74,8392,36,5429,0.170825444,1.329764763,0.879999016,2.042379986,0.311934892,DB0033510020642_,1.164960794,0.285002056,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,atenolol,DB00335
,7235,DB00641,10020642,101,14023,65,12410,0.050877536,1.375095121,0.996054432,1.909808537,0.12665177,DB0064110020642_,2.066313924,0.318522907,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,7237,DB00153,10020751,117,7306,19,3420,2.58570316878924e-06,2.882338581,1.762136297,4.967065832,3.31780365104345e-05,DB0015310020751_,10.31362245,1.058601972,female,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ergocalciferol,DB00153
,7238,DB00316,10020751,582,64892,248,36705,0.000181984,1.327407264,1.141456637,1.547236524,0.001331696,DB0031610020751_,6.621301604,0.283227614,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,acetaminophen,DB00316
,7239,DB00335,10020751,85,8381,32,5433,0.007715517,1.721854091,1.132554263,2.67679077,0.02894489,DB0033510020751_,3.542361603,0.54340167,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,atenolol,DB00335
,7240,DB00641,10020751,122,14002,71,12404,0.004714684,1.522176684,1.125708258,2.071514902,0.019511212,DB0064110020751_,3.936766007,0.420141339,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,simvastatin,DB00641
,7241,DB14512,10020751,67,4777,28,2384,0.510788679,1.19412497,0.755335943,1.933784859,0.671136238,DB1451210020751_,0.398783126,0.177413675,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,mometasone furoate,DB14512
,7242,DB00153,10020937,121,7302,36,3403,0.019317515,1.566341869,1.069087228,2.345708384,0.060161674,DB0015310020937_,2.810719773,0.448742881,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,7243,DB00316,10020937,821,64653,289,36664,8.09792708907153e-13,1.610995695,1.406283169,1.849664756,3.6762351215241e-11,DB0031610020937_,24.02654686,0.476852432,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,7244,DB00335,10020937,108,8358,44,5421,0.009443322,1.59196685,1.109428583,2.318819629,0.0340001,DB0033510020937_,3.38139182,0.464970264,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,7245,DB00641,10020937,176,13948,89,12386,1.33499205373833e-05,1.756027472,1.35162817,2.294975162,0.000139969,DB0064110020937_,8.87408851,0.56305414,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,7246,DB06643,10020937,295,52126,41,7474,0.934154936,1.03166211,0.74157146,1.468897762,0.974704265,DB0664310020937_,0.025621172,0.031171201,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,7249,DB00316,10024570,100,65374,32,36921,0.00474205,1.764882942,1.174519607,2.717290888,0.019596696,DB0031610024570_,3.932394287,0.568084366,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,7254,DB00153,10028372,83,7340,41,3398,0.770929746,0.937183732,0.635672242,1.400985447,0.874560905,DB0015310028372_,0.134033341,-0.064875931,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,7255,DB00316,10028372,495,64979,324,36629,0.040723132,0.861223443,0.746699102,0.994380362,0.107088941,DB0031610028372_,2.234095562,-0.149401293,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,7256,DB00335,10028372,91,8375,51,5414,0.437959697,1.153491805,0.808390007,1.661610328,0.606409284,DB0033510028372_,0.500200136,0.142793694,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,7257,DB00641,10028372,144,13980,140,12335,0.43727468,0.907545161,0.713206932,1.155094548,0.605708272,DB0064110028372_,0.501356808,-0.09701195,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,7258,DB06643,10028372,200,52221,54,7461,8.71338827650076e-05,0.529191225,0.389609646,0.729401427,0.000709295,DB0664310028372_,7.251238797,-0.636405429,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,7261,DB00316,10034568,64,65410,29,36924,0.387510627,1.245832276,0.791448611,2.004619546,0.557541016,DB0031610034568_,0.584219207,0.219803801,NA,10034568,Peripheral coldness,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,7266,DB00153,10042674,68,7355,12,3427,0.000988983,2.640143193,1.4152491,5.366116504,0.0054532,DB0015310042674_,5.211552632,0.970833155,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,7267,DB00316,10042674,450,65024,179,36774,5.22747795104238e-05,1.421756384,1.192434155,1.701124485,0.000458779,DB0031610042674_,7.686942328,0.351892998,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,7268,DB00335,10042674,73,8393,25,5440,0.004929834,1.892540751,1.185467051,3.115668804,0.020246491,DB0033510042674_,3.899773779,0.637920239,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,7270,DB00153,10042772,45,7378,30,3409,0.134596586,0.693087352,0.426330144,1.141616215,0.262090823,DB0015310042772_,1.339064184,-0.366599239,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,7271,DB00316,10042772,410,65064,260,36693,0.146234492,0.889313932,0.759061382,1.043417852,0.278726198,DB0031610042772_,1.277525348,-0.117304976,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,7272,DB00335,10042772,52,8414,63,5402,0.000746004,0.529968054,0.359254198,0.778819363,0.004315776,DB0033510042772_,5.445478241,-0.634938549,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,7273,DB00641,10042772,103,14021,108,12367,0.213342579,0.841206406,0.635173628,1.113530287,0.365456095,DB0064110042772_,1.006609131,-0.17291822,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,7274,DB06643,10042772,54,52367,28,7487,3.63502784803593e-07,0.275713014,0.17149355,0.452395682,5.80301894841326e-06,DB0664310042772_,12.05713227,-1.28839476,male,10042772,Syncope,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,7277,DB00316,10057372,64,65410,11,36942,5.48859304707404e-05,3.285931293,1.718778105,6.909740922,0.000478262,DB0031610057372_,7.645352302,1.18965011,female,10057372,Paraesthesia oral,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,7284,DB00433,10033645,30,7626,21,5999,0.77789095,1.123746848,0.621624902,2.067331318,0.878905761,DB0043310033645_,0.129077599,0.116668502,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,7285,DB00722,10033645,123,25280,131,25901,0.801397219,0.961987048,0.745514041,1.240751202,0.892535197,DB0072210033645_,0.11368933,-0.038754292,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,7286,DB00904,10033645,103,22966,76,14380,0.281935499,0.848597547,0.624308704,1.157753488,0.445888965,DB0090410033645_,0.807685316,-0.164170236,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,7288,DB00996,10033645,91,38862,62,22363,0.31372298,0.844616532,0.604687701,1.186489701,0.481207279,DB0099610033645_,0.731457168,-0.168872563,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,7289,DB01067,10033645,40,4321,32,4791,0.192574639,1.385905835,0.847221516,2.283859059,0.339913668,DB0106710033645_,1.079063611,0.326353958,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,glipizide,DB01067
,7291,DB00489,10017955,26,1057,33,1101,0.510131822,0.820750056,0.46795806,1.425804709,0.670606515,DB0048910017955_,0.399572729,-0.197536655,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,sotalol,DB00489
,7292,DB00682,10017955,394,19065,665,15699,7.8506827585141e-30,0.487881312,0.428839833,0.554489951,1.71962663589619e-27,DB0068210017955_,61.62769032,-0.717683115,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,7310,DB00374,10013709,147,17569,59,5665,0.16595848,0.803376097,0.589137129,1.107712126,0.305370574,DB0037410013709_,1.186229243,-0.218932309,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,7312,DB14726,10017955,309,1708,398,2450,0.200557482,1.113635912,0.944633775,1.312063846,0.349706685,DB1472610017955_,1.05066052,0.107630258,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,dabigatran,DB14726
,7314,DB00005,10054107,433,127649,84,42335,2.52688372685248e-06,1.709508824,1.350153921,2.186824723,3.25185501886499e-05,DB0000510054107_,10.33369986,0.536206092,NA,10054107,Nodule,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,7315,DB00363,10042458,56,4572,48,6840,0.004842674,1.74526688,1.163405159,2.627129569,0.019954488,DB0036310042458_,3.914301219,0.556907484,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,7323,DB00515,10012174,109,1761,79,2072,0.001596076,1.623198283,1.195106179,2.212680904,0.008082623,DB0051510012174_,4.818038813,0.484398452,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,cisplatin,DB00515
,7327,DB00515,10021036,41,1829,47,2104,1,1.00350077,0.64042458,1.566847761,1,DB0051510021036_,0,0.003494657,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,cisplatin,DB00515
,7331,DB00515,10038695,34,1836,39,2112,1,1.002848383,0.611299255,1.638019709,1,DB0051510038695_,0,0.002844334,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cisplatin,DB00515
,7339,DB00186,10022000,142,16759,93,9915,0.456305031,0.903342912,0.6897509,1.187728248,0.623693329,DB0018610022000_,0.472096491,-0.10165305,NA,10022000,Influenza,10021881,Infections and infestations,Infec,lorazepam,DB00186
,7340,DB00656,10022000,126,11887,50,6569,0.04807465,1.392580065,0.994542242,1.976019864,0.121480693,DB0065610022000_,2.107999935,0.331158189,NA,10022000,Influenza,10021881,Infections and infestations,Infec,trazodone,DB00656
,7341,DB01234,10022000,349,31276,374,32514,0.708379565,0.97008669,0.835275322,1.126414478,0.825838018,DB0123410022000_,0.191356629,-0.03036984,NA,10022000,Influenza,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,7342,DB08910,10022000,332,16412,387,17101,0.141536547,0.893899529,0.768411595,1.039427786,0.271965593,DB0891010022000_,1.302079717,-0.112161894,NA,10022000,Influenza,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,7343,DB00186,10029366,108,16793,49,9959,0.135871639,1.307106358,0.923409472,1.873231264,0.26391177,DB0018610029366_,1.332140438,0.267815807,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,lorazepam,DB00186
,7345,DB01234,10029366,199,31426,181,32707,0.198381277,1.144260336,0.930279975,1.408156239,0.347155145,DB0123410029366_,1.057983495,0.134758434,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,7346,DB08910,10029366,102,16642,124,17364,0.257296382,0.85827215,0.653294796,1.125456273,0.418168268,DB0891010029366_,0.871871372,-0.152834039,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,pomalidomide,DB08910
,7347,DB00186,10035664,615,16286,420,9588,0.023603648,0.862073733,0.758242667,0.980828494,0.070302763,DB0018610035664_,2.654944171,-0.148414474,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,lorazepam,DB00186
,7348,DB00656,10035664,341,11672,197,6422,0.615144311,0.952393354,0.794664533,1.143921028,0.756553818,DB0065610035664_,0.278981607,-0.048777143,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,trazodone,DB00656
,7349,DB01234,10035664,1570,30055,1994,30894,1.02074206619219e-09,0.809345982,0.755619607,0.866770061,2.83168392716218e-08,DB0123410035664_,17.37980918,-0.211528787,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,7350,DB00186,10047942,280,16621,133,9875,0.035407321,1.250752166,1.012323638,1.551763041,0.096303956,DB0018610047942_,2.340245884,0.223745103,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,lorazepam,DB00186
,7351,DB00656,10047942,94,11919,36,6583,0.065816639,1.442119615,0.971210238,2.183371352,0.153811101,DB0065610047942_,1.872030043,0.366113986,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,trazodone,DB00656
,7352,DB01234,10047942,690,30935,629,32259,0.016680993,1.143926045,1.024097279,1.278004138,0.053585077,DB0123410047942_,2.926484667,0.134466245,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,7353,DB08910,10047942,541,16203,541,16947,0.47732677,1.045933296,0.924874905,1.182833691,0.642719847,DB0891010047942_,0.442046346,0.044909593,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,pomalidomide,DB08910
,7354,DB00005,10049548,278,127804,88,42331,0.762229467,1.04637945,0.820260489,1.34583051,0.868285351,DB0000510049548_,0.141234873,0.045336062,NA,10049548,Knee operation,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,7356,DB00215,10003239,266,10837,70,5206,3.74719651512791e-06,1.825426695,1.394879184,2.415775693,4.5864987380739e-05,DB0021510003239_,9.989808534,0.601813765,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,7357,DB00490,10003239,116,3954,27,1549,0.013952988,1.682965667,1.094211678,2.673288607,0.046442231,DB0049010003239_,3.069546086,0.520557515,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,buspirone,DB00490
,7358,DB00555,10003239,131,6916,21,3465,7.31315616841011e-08,3.125093445,1.95770613,5.227500089,1.36379077606711e-06,DB0055510003239_,13.5052424,1.139464185,female,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lamotrigine,DB00555
,7370,DB00158,10010264,445,16370,145,7959,2.29146596592575e-05,1.492091,1.231831618,1.815881015,0.000224283,DB0015810010264_,8.402602189,0.400178492,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,7371,DB00215,10010264,190,10913,68,5208,0.043910968,1.333449676,1.003640655,1.789554958,0.113418149,DB0021510010264_,2.176673853,0.287769326,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,7372,DB00490,10010264,106,3964,33,1543,0.2929826,1.250263154,0.834659082,1.91711807,0.458559465,DB0049010010264_,0.779665302,0.223354052,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,7373,DB00555,10010264,134,6913,48,3438,0.056324976,1.388322022,0.988701865,1.978251982,0.136684853,DB0055510010264_,1.990077345,0.328095839,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,7375,DB00215,10019211,514,10589,113,5163,5.91563065783178e-16,2.217754389,1.800561591,2.750863062,4.05455937004194e-14,DB0021510019211_,30.83634928,0.796495147,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,7376,DB00490,10019211,216,3854,53,1523,0.001701329,1.610397265,1.179923028,2.231151226,0.0085115,DB0049010019211_,4.766337096,0.476480897,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,buspirone,DB00490
,7377,DB00555,10019211,325,6722,120,3366,0.004630609,1.356143856,1.091941425,1.693299701,0.019222291,DB0055510019211_,3.951684659,0.304645273,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,7384,DB00158,10033425,569,16246,158,7946,8.15564526845967e-11,1.761360573,1.471054653,2.118855841,2.69141413536048e-09,DB0015810033425_,19.73319908,0.566086564,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,7385,DB00215,10033425,230,10873,55,5221,1.02783728721324e-06,2.007951659,1.48742388,2.751449017,1.46431995091599e-05,DB0021510033425_,11.13153453,0.697115127,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,7386,DB00490,10033425,109,3961,18,1558,0.000283659,2.381566304,1.432359313,4.183212557,0.001928456,DB0049010033425_,6.251035594,0.867758382,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,buspirone,DB00490
,7387,DB00555,10033425,88,6959,26,3460,0.020924625,1.682748001,1.073540159,2.721784199,0.064054479,DB0055510033425_,2.74802133,0.520428172,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,lamotrigine,DB00555
,7405,DB00196,10007515,30,5053,48,3237,9.36390512853104e-05,0.400423967,0.244390476,0.646506953,0.000754422,DB0019610007515_,7.189558385,-0.915231375,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,fluconazole,DB00196
,7406,DB00316,10007515,656,64818,492,36461,2.18053738709878e-06,0.750041075,0.665788042,0.845350734,2.86005115867722e-05,DB0031610007515_,10.46208595,-0.287627308,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,7407,DB01118,10007515,88,2975,122,4587,0.474297781,1.112135723,0.832341023,1.481043061,0.639993737,DB0111810007515_,0.446296889,0.106282242,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,amiodarone,DB01118
,7409,DB00381,10051118,62,29298,30,22857,0.034976206,1.612304529,1.026367537,2.584058981,0.095372127,DB0038110051118_,2.349968916,0.47766454,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,7410,DB00404,10051118,51,19841,16,9846,0.119356368,1.58175886,0.886909996,2.973467826,0.240358715,DB0040410051118_,1.425622825,0.45853743,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,7412,DB00722,10051118,60,25343,54,25978,0.512408706,1.138947691,0.774991982,1.677329326,0.672609196,DB0072210051118_,0.396590808,0.130104758,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,7416,DB00559,10003549,360,9299,86,3220,0.001929524,1.449429182,1.138480454,1.862504658,0.009456053,DB0055910003549_,4.661100237,0.371169811,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,7417,DB00203,10011224,870,13008,257,8681,6.83339166930609e-33,2.259058756,1.957917414,2.613428859,1.8143000002799e-30,DB0020310011224_,68.48185307,0.814948247,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,7418,DB00559,10011224,446,9213,140,3166,0.382748317,1.094745687,0.899327456,1.339068229,0.552862869,DB0055910011224_,0.592645285,0.090522087,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,7419,DB00203,10012735,1597,12281,583,8355,2.16440301989561e-37,1.86352088,1.68686385,2.060672926,7.58551111706082e-35,DB0020310012735_,78.56423826,0.622467645,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,7420,DB00203,10044565,124,13754,68,8870,0.299271788,1.17595378,0.866860321,1.606987084,0.465272311,DB0020310044565_,0.76513243,0.162079546,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,7421,DB00559,10044565,49,9610,14,3292,0.663998207,1.198938008,0.650358382,2.354729141,0.795391547,DB0055910044565_,0.228920774,0.181436172,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,bosentan,DB00559
,7422,DB00983,10053762,54,3447,31,1709,0.561674575,0.863672999,0.543062926,1.395440458,0.714028786,DB0098310053762_,0.336832001,-0.146561055,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,formoterol,DB00983
,7423,DB00005,10020937,1076,127006,356,42063,1,1.001009695,0.886670681,1.132218872,1,DB0000510020937_,0,0.001009185,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,7424,DB00005,10027599,689,127393,91,42328,3.78282127885055e-20,2.515829833,2.018718363,3.1665951,3.96141264201541e-18,DB0000510027599_,40.06993098,0.922602702,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,7425,DB00285,10012735,449,10502,120,3598,0.018204993,1.281861775,1.041847585,1.586993688,0.057358699,DB0028510012735_,2.858430769,0.248313533,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,7426,DB01241,10012735,57,886,60,1011,0.703092671,1.083980519,0.732201302,1.60330115,0.821845538,DB0124110012735_,0.196202811,0.080639931,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,gemfibrozil,DB01241
,7427,DB01241,10013700,123,820,83,988,0.000118558,1.784996345,1.318855792,2.425450959,0.000921978,DB0124110013700_,6.988989613,0.579416367,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,gemfibrozil,DB01241
,7428,DB00285,10016256,677,10274,174,3544,0.000639331,1.342066195,1.129310384,1.601690703,0.003799844,DB0028510016256_,5.572795196,0.294210363,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,7429,DB01241,10016256,55,888,62,1009,1,1.007970431,0.680020101,1.49077308,1,DB0124110016256_,0,0.007938835,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,gemfibrozil,DB01241
,7430,DB00285,10037844,215,10736,49,3669,0.010044508,1.499416118,1.092293483,2.094007002,0.035700074,DB0028510037844_,3.332602507,0.405075778,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,venlafaxine,DB00285
,7432,DB01104,10013700,953,14510,223,7063,8.49971412011342e-25,2.080162459,1.790830586,2.424227833,1.27665706084104e-22,DB0110410013700_,50.41262706,0.732445996,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,sertraline,DB01104
,7433,DB01104,10039897,39,15424,31,7255,0.039108912,0.591762937,0.359485503,0.981785766,0.103851871,DB0110410039897_,2.26478971,-0.524649169,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,7436,DB00563,10013968,791,45855,218,15130,0.018614928,1.197206718,1.028037604,1.398908494,0.058391717,DB0056310013968_,2.840581231,0.179991108,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,7438,DB00698,10013968,101,3047,11,418,0.55575443,1.25952433,0.667586109,2.625359511,0.709143678,DB0069810013968_,0.343697125,0.230734134,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nitrofurantoin,DB00698
,7439,DB00787,10013968,478,16522,423,16825,0.039413188,1.150741624,1.005675006,1.317083884,0.104469887,DB0078710013968_,2.25885641,0.140406625,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,7441,DB00999,10013968,861,20569,358,11881,1.74735840118507e-07,1.389171322,1.224011994,1.579098019,3.00781372463323e-06,DB0099910013968_,12.71429708,0.328707398,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,7446,DB00924,10016256,668,9494,199,4052,9.65452264932758e-06,1.432629333,1.215642943,1.694130916,0.00010543,DB0092410016256_,9.157466809,0.35951145,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,7447,DB00999,10016256,1547,19883,721,11518,2.54938396619862e-06,1.242909444,1.133633851,1.363724354,3.27599890254367e-05,DB0099910016256_,10.32630263,0.217454957,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,7448,DB00175,10021143,53,8078,33,6073,0.444807374,1.207412087,0.766332431,1.92772588,0.612888204,DB0017510021143_,0.489572735,0.188479298,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,7449,DB00264,10021143,161,29446,166,24726,0.066219343,0.814420249,0.651141184,1.018460008,0.15455296,DB0026410021143_,1.867218458,-0.20527877,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,7452,DB00563,10021143,81,46565,85,15263,3.21966606017202e-13,0.312356189,0.227393846,0.428812263,1.54291563157013e-11,DB0056310021143_,24.89476213,-1.163611111,male,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,7455,DB00787,10021143,68,16932,85,17163,0.224104128,0.810920619,0.580226826,1.129620261,0.378681303,DB0078710021143_,0.971060317,-0.20958511,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,7457,DB00924,10021143,35,10127,23,4228,0.111235528,0.63534446,0.364451823,1.127688531,0.227908532,DB0092410021143_,1.478810904,-0.453587971,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,7458,DB00997,10021143,41,5290,42,3472,0.054691064,0.640758025,0.40542312,1.01195406,0.133810324,DB0099710021143_,2.011331974,-0.44510339,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxorubicin,DB00997
,7459,DB00999,10021143,55,21375,44,12195,0.095152547,0.713189969,0.470723735,1.086100624,0.203439458,DB0099910021143_,1.592386822,-0.338007457,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,7489,DB00563,10038687,43,46603,45,15303,1.48902616705107e-07,0.313768803,0.20158675,0.487773533,2.60666352320596e-06,DB0056310038687_,12.8574395,-1.159098862,male,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,7492,DB00787,10038687,18,16982,32,17216,0.065063605,0.570263304,0.301254998,1.047526342,0.152539523,DB0078710038687_,1.880331548,-0.561657088,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,7494,DB00996,10038687,58,38895,44,22381,0.18099409,0.7585314,0.503635437,1.149552137,0.325105385,DB0099610038687_,1.123605888,-0.276371084,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,7497,DB00175,10043071,30,8101,20,6086,0.775139154,1.126853368,0.618461229,2.095769537,0.877413689,DB0017510043071_,0.130776688,0.119429118,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,pravastatin,DB00175
,7498,DB00264,10043071,186,29421,130,24762,0.112743447,1.204193049,0.956663884,1.519484069,0.230194774,DB0026410043071_,1.468829483,0.185809674,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,metoprolol,DB00264
,7502,DB00787,10043071,70,16930,75,17173,0.802947379,0.946712448,0.673135461,1.330102743,0.893342905,DB0078710043071_,0.11278478,-0.054759877,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,acyclovir,DB00787
,7503,DB00924,10043071,67,10095,22,4229,0.352687624,1.27575614,0.776789794,2.172338858,0.522452333,DB0092410043071_,0.649221528,0.243539054,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,cyclobenzaprine,DB00924
,7504,DB00996,10043071,174,38779,103,22322,0.851232966,0.97238999,0.757329188,1.253854068,0.926736328,DB0099610043071_,0.07608619,-0.027998331,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,gabapentin,DB00996
,7505,DB00999,10043071,86,21344,53,12186,0.65955961,0.926423239,0.649880587,1.33134434,0.792035804,DB0099910043071_,0.233148681,-0.076424087,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,7532,DB00175,10070863,32,8099,52,6054,0.000538035,0.46002075,0.286185421,0.729210839,0.00327822,DB0017510070863_,5.720454817,-0.776483682,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,7533,DB00264,10070863,717,28890,497,24395,0.000802668,1.218187437,1.083570645,1.370360819,0.004587544,DB0026410070863_,5.384410455,0.197364047,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,7538,DB00787,10070863,64,16936,71,17177,0.606311791,0.914254668,0.641310202,1.301034361,0.749302055,DB0078710070863_,0.288613098,-0.089646117,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,7540,DB00924,10070863,470,9692,244,4007,0.00545176,0.796351427,0.677740357,0.937600873,0.021919621,DB0092410070863_,3.820373103,-0.227714699,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,7541,DB00996,10070863,1214,37739,778,21647,0.018018346,0.895052561,0.816038073,0.982141114,0.056893775,DB0099610070863_,2.866569352,-0.110872835,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,7542,DB00997,10070863,80,5251,40,3474,0.159525506,1.323135353,0.892015687,1.990333304,0.296816588,DB0099710070863_,1.21464088,0.280004187,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,doxorubicin,DB00997
,7543,DB00999,10070863,218,21212,207,12032,1.95284501653298e-07,0.597347744,0.490956696,0.727067701,3.32128963180649e-06,DB0099910070863_,12.61515741,-0.515255849,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,7544,DB08896,10013709,30,793,48,992,0.351597752,0.781943582,0.473597758,1.272871844,0.521337333,DB0889610013709_,0.651357974,-0.245972687,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,regorafenib,DB08896
,7581,DB00060,10022437,131,9377,36,2429,0.772431589,0.942608215,0.64558126,1.407681494,0.875421786,DB0006010022437_,0.133049467,-0.059104549,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,interferon beta-1a,DB00060
,7582,DB00108,10005750,41,10153,9,3286,0.326824529,1.474328019,0.704888776,3.453876751,0.495259353,DB0010810005750_,0.702673707,0.388202306,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,natalizumab,DB00108
,7583,DB00005,10013781,366,127716,78,42341,0.000274758,1.555565962,1.214965317,2.013450711,0.001879021,DB0000510013781_,6.277004248,0.441839442,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,7584,DB00005,10015929,169,127913,29,42390,0.000529028,1.931132419,1.296582928,2.971807657,0.003231961,DB0000510015929_,5.734666346,0.658106576,NA,10015929,Eye infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,7585,DB00005,10038683,143,127939,48,42371,0.933325124,0.986643915,0.706765027,1.398649021,0.973973753,DB0000510038683_,0.026370924,-0.013446079,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,7586,DB00158,10006451,265,16550,48,8056,5.42607045963181e-12,2.687270844,1.967351266,3.739657566,2.17249447115647e-10,DB0015810006451_,22.2499749,0.988526122,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,folic acid,DB00158
,7587,DB00381,10006451,276,29084,119,22768,2.41580094690392e-08,1.815619353,1.458243832,2.272138122,4.98033944230348e-07,DB0038110006451_,14.5125976,0.596426651,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,amlodipine,DB00381
,7588,DB00563,10006451,454,46192,61,15287,2.78996396571011e-13,2.463207985,1.880762045,3.275324742,1.35678451135412e-11,DB0056310006451_,25.02331845,0.901464559,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,methotrexate,DB00563
,7589,DB00635,10006451,530,32523,128,23666,1.9369156717869e-34,3.012898156,2.477759054,3.686419029,5.75274897547105e-32,DB0063510006451_,71.93304515,1.102902458,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,prednisone,DB00635
,7590,DB00678,10006451,184,15415,64,10660,9.3908444668429e-07,1.98810323,1.486567343,2.688380059,1.354394221185e-05,DB0067810006451_,11.20957118,0.687181033,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,losartan,DB00678
,7591,DB00158,10016322,200,16615,65,8039,0.005514201,1.488716011,1.118524077,2.003638065,0.022123295,DB0015810016322_,3.811124171,0.397914011,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,7592,DB00381,10016322,502,28858,229,22658,3.88853721237296e-12,1.721148473,1.467732902,2.02322607,1.58834810609516e-10,DB0038110016322_,22.56315638,0.542991785,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,7593,DB00635,10016322,426,32627,186,23608,4.32452186284178e-09,1.657195625,1.390545289,1.981135848,1.05347597001665e-07,DB0063510016322_,16.06600051,0.505126791,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,7594,DB00678,10016322,287,15312,119,10605,1.58521789527674e-06,1.670339185,1.342308315,2.089221918,2.16398090767847e-05,DB0067810016322_,10.74097593,0.51302671,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,7602,DB00005,10033775,887,127195,256,42163,0.054498918,1.148534162,0.997857542,1.325728683,0.133448605,DB0000510033775_,2.014038858,0.138486488,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,7607,DB00374,10035664,1017,16699,312,5412,0.430166987,1.056401366,0.926116078,1.207644177,0.598630837,DB0037410035664_,0.51311017,0.054868194,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,treprostinil,DB00374
,7608,DB00635,10035664,1362,31691,1029,22765,0.235657445,0.950834604,0.874639788,1.033836367,0.392812223,DB0063510035664_,0.934423584,-0.05041515,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,prednisone,DB00635
,7609,DB00641,10035664,463,13661,448,12027,0.166100346,0.909870448,0.795423631,1.040871293,0.30556744,DB0064110035664_,1.185584771,-0.094453054,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,simvastatin,DB00641
,7610,DB00695,10035664,1595,26454,1125,19403,0.337652893,1.039890881,0.960704257,1.125847843,0.506821591,DB0069510035664_,0.679596229,0.039115786,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,furosemide,DB00695
,7611,DB00820,10035664,907,11008,308,5508,5.34706333506719e-09,1.473442084,1.287957574,1.689083154,1.2765445936625e-07,DB0082010035664_,15.87393876,0.387601217,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,tadalafil,DB00820
,7612,DB00973,10035664,98,3753,99,2922,0.080278562,0.770748418,0.574398117,1.034144401,0.178861793,DB0097310035664_,1.721141879,-0.260393265,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ezetimibe,DB00973
,7613,DB00996,10035664,1307,37646,954,21471,1.7463876900386e-08,0.781395896,0.717040456,0.851699884,3.70640294167659e-07,DB0099610035664_,14.8080338,-0.246673349,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,gabapentin,DB00996
,7614,DB00559,10038687,87,9572,67,3239,9.84915548596072e-07,0.439420588,0.315031585,0.615241974,1.41158697899933e-05,DB0055910038687_,11.16821088,-0.822298265,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,7615,DB00635,10038687,127,32926,88,23706,0.835481537,1.039063117,0.785095437,1.380315295,0.914862473,DB0063510038687_,0.088981527,0.038319458,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,7616,DB00641,10038687,30,14094,31,12444,0.607884946,0.854453793,0.499326692,1.460187817,0.750716773,DB0064110038687_,0.286726832,-0.157292853,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,7617,DB00695,10038687,136,27913,108,20420,0.558851372,0.921224305,0.709821453,1.198024485,0.711730622,DB0069510038687_,0.340055779,-0.082051727,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,7619,DB00451,10040047,410,46861,196,15223,1.53136681268791e-05,0.67954714,0.571201491,0.810643981,0.00015782,DB0045110040047_,8.754055771,-0.386328673,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,7620,DB00559,10040047,153,9506,65,3241,0.158001961,0.802527516,0.594859901,1.093079273,0.294782691,DB0055910040047_,1.221516836,-0.219989137,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,bosentan,DB00559
,7621,DB00635,10040047,473,32580,429,23365,0.000515169,0.790722545,0.691605451,0.904216243,0.003163835,DB0063510040047_,5.755970344,-0.234808137,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,prednisone,DB00635
,7622,DB00641,10040047,107,14017,152,12323,0.000163653,0.618890718,0.478119765,0.798809194,0.001214977,DB0064110040047_,6.713030066,-0.479826568,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,simvastatin,DB00641
,7623,DB00695,10040047,424,27625,410,20118,5.44135557940446e-05,0.753133815,0.655127217,0.865830337,0.000474539,DB0069510040047_,7.653166914,-0.283512357,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,furosemide,DB00695
,7624,DB00820,10040047,204,11711,76,5740,0.046501423,1.315650289,1.004170909,1.738796615,0.118496354,DB0082010040047_,2.132873087,0.27433106,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,tadalafil,DB00820
,7626,DB00996,10040047,376,38577,306,22119,7.23850931207558e-06,0.704565785,0.603664113,0.82276724,8.17813098078258e-05,DB0099610040047_,9.411461827,-0.350173574,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,gabapentin,DB00996
,7628,DB06228,10018867,284,15628,585,15491,8.7621649681665e-25,0.481227907,0.415424368,0.556467755,1.31232767058836e-22,DB0622810018867_,50.38506964,-0.731414301,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,rivaroxaban,DB06228
,7629,DB06228,10029148,32,15880,33,16043,1,0.979648034,0.582905165,1.644536032,1,DB0622810029148_,0,-0.020561921,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,rivaroxaban,DB06228
,7630,DB06228,10055798,504,15408,687,15389,1.92521149020252e-07,0.732730058,0.650438398,0.825014498,3.27959714970663e-06,DB0622810055798_,12.62778996,-0.310977915,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,rivaroxaban,DB06228
,7631,DB00515,10012735,132,1738,77,2074,7.52718979019372e-07,2.045359405,1.520914959,2.76593736,1.11434628913119e-05,DB0051510012735_,11.40465752,0.715573522,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cisplatin,DB00515
,7632,DB00515,10013968,81,1789,95,2056,0.938457013,0.97988555,0.714310477,1.341615295,0.978144719,DB0051510013968_,0.022097646,-0.0203195,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cisplatin,DB00515
,7633,DB00515,10016256,136,1734,119,2032,0.027263955,1.339157192,1.030367102,1.742453503,0.078578187,DB0051510016256_,2.543661137,0.292040455,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cisplatin,DB00515
,7634,DB00515,10021015,65,1805,25,2126,8.98955029769385e-07,3.061572355,1.894222801,5.091622833,1.30475057744275e-05,DB0051510021015_,11.24691357,1.118928625,female,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,cisplatin,DB00515
,7635,DB00515,10028813,268,1602,160,1991,1.56073463629531e-12,2.081366887,1.685500401,2.57608446,6.78642016791104e-11,DB0051510028813_,23.41351244,0.733024835,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cisplatin,DB00515
,7636,DB00515,10037660,115,1755,134,2017,0.947742494,0.986331284,0.755597788,1.285936046,0.9862195,DB0051510037660_,0.013876332,-0.013762993,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,cisplatin,DB00515
,7638,DB00515,10047700,199,1671,123,2028,1.27364259369283e-08,1.963233207,1.545022116,2.502073718,2.7956321983479e-07,DB0051510047700_,15.09003738,0.67459271,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cisplatin,DB00515
,7642,DB00904,10002198,89,22980,53,14403,0.796096976,1.052491509,0.740294617,1.509017558,0.889553383,DB0090410002198_,0.117035759,0.051160219,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,ondansetron,DB00904
,7643,DB00927,10002198,65,7432,31,4985,0.142900492,1.406369603,0.902013456,2.235905662,0.273890874,DB0092710002198_,1.295025522,0.341011634,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,famotidine,DB00927
,7646,DB00904,10003988,540,22529,262,14194,0.000558694,1.298525226,1.11657584,1.513143186,0.003383316,DB0090410003988_,5.688898902,0.261229179,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,7647,DB00927,10003988,182,7315,83,4933,0.003491069,1.478688613,1.131450543,1.945934828,0.01529379,DB0092710003988_,4.180308403,0.391155623,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,famotidine,DB00927
,7648,DB01248,10003988,88,2612,40,1334,0.570315511,1.123566102,0.759921529,1.686360039,0.720916765,DB0124810003988_,0.327231592,0.116507646,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,docetaxel,DB01248
,7650,DB00904,10025482,758,22311,272,14184,1.14189740972413e-16,1.771629494,1.537845552,2.045861336,8.47874955214658e-15,DB0090410025482_,32.40121341,0.571899741,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,7651,DB00927,10025482,218,7279,86,4930,1.82780460051745e-05,1.716779607,1.32791762,2.236011074,0.000184448,DB0092710025482_,8.598142185,0.540450215,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,7652,DB01248,10025482,59,2641,22,1352,0.235728779,1.372794812,0.8244644,2.363490874,0.39287454,DB0124810025482_,0.934264955,0.31684867,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,7659,DB00497,10012601,46,19221,52,16323,0.186764044,0.751250561,0.493760672,1.139751618,0.332447966,DB0049710012601_,1.101271925,-0.286016047,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,7660,DB08910,10012601,33,16711,62,17426,0.007218973,0.55504347,0.352173155,0.860551942,0.027432515,DB0891010012601_,3.596026308,-0.588708843,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,pomalidomide,DB08910
,7662,DB08911,10013968,35,1604,32,1716,0.539396093,1.170065664,0.699851809,1.962265479,0.69521917,DB0891110013968_,0.363528131,0.157059871,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trametinib,DB08911
,7663,DB00497,10016173,548,18719,355,16020,4.86766512801836e-05,1.321076465,1.151843465,1.516712687,0.000432033,DB0049710016173_,7.747008545,0.278446908,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,7664,DB08910,10016173,388,16356,324,17164,0.002747804,1.256677912,1.079770369,1.463338492,0.012582932,DB0891010016173_,4.375413964,0.228471661,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,pomalidomide,DB08910
,7666,DB00497,10018884,168,19099,131,16244,0.484557092,1.090769222,0.861896049,1.382679056,0.648694768,DB0049710018884_,0.432792984,0.086883155,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,oxycodone,DB00497
,7667,DB08910,10018884,177,16567,183,17305,0.957745684,1.010299576,0.816102588,1.250492292,0.995446541,DB0891010018884_,0.004563857,0.010246897,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,pomalidomide,DB08910
,7669,DB00497,10019663,18,19249,35,16340,0.003602606,0.436571988,0.232681129,0.792359696,0.015680495,DB0049710019663_,4.155337707,-0.828801996,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,oxycodone,DB00497
,7672,DB00497,10029331,261,19006,220,16155,0.9632699,1.008402977,0.838466885,1.213619571,1,DB0049710029331_,0,0.008367869,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,7673,DB08910,10029331,415,16329,396,17092,0.200667585,1.096939376,0.951890865,1.264243429,0.349782651,DB0891010029331_,1.050443315,0.092523917,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,7675,DB00497,10035226,205,19062,244,16131,0.000345311,0.710992266,0.586868045,0.860668665,0.002269408,DB0049710035226_,6.088236317,-0.341093727,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,oxycodone,DB00497
,7676,DB08910,10035226,1096,15648,1266,16222,0.011826593,0.897478319,0.824545566,0.976783154,0.040699398,DB0891010035226_,3.201541984,-0.108166316,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pomalidomide,DB08910
,7678,DB00497,10037844,400,18867,319,16056,0.405699421,1.067115296,0.917391473,1.242039419,0.575287097,DB0049710037844_,0.552886063,0.064959023,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,7679,DB08910,10037844,362,16382,341,17147,0.170100471,1.11115303,0.954188252,1.294155736,0.310999957,DB0891010037844_,1.167962506,0.105398242,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,pomalidomide,DB08910
,7680,DB08911,10037844,136,1503,129,1619,0.337142421,1.135586744,0.876551164,1.471698917,0.506301121,DB0891110037844_,0.680623685,0.127149472,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,trametinib,DB08911
,7681,DB00497,10047942,278,18989,183,16192,0.0072826,1.295353693,1.069719312,1.571630411,0.027619061,DB0049710047942_,3.589249125,0.258783779,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,oxycodone,DB00497
,7683,DB00668,10046571,280,9811,26,4277,6.45593521157008e-20,4.694764729,3.130703975,7.326301726,6.59006823441241e-18,DB0066810046571_,39.56096797,1.546448,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,epinephrine,DB00668
,7684,DB01075,10046571,481,19467,77,11020,1.18421800881903e-31,3.536078999,2.771609675,4.563926191,2.93652550583097e-29,DB0107510046571_,65.69774062,1.263018486,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,7687,DB09153,10046571,234,7565,52,5647,2.92618804031359e-18,3.358764337,2.47244096,4.637640634,2.58103532347794e-16,DB0915310046571_,35.89317088,1.211573149,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,7703,DB08882,10013968,36,961,32,961,0.711564498,1.124932871,0.673026754,1.887728222,0.828118609,DB0888210013968_,0.188598887,0.117723364,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,linagliptin,DB08882
,7706,DB00448,10010774,94,5051,60,3064,0.801384729,0.950375156,0.677946018,1.341027827,0.892535197,DB0044810010774_,0.11368933,-0.050898471,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,lansoprazole,DB00448
,7707,DB00741,10010774,86,4008,70,3104,0.806723105,0.951444807,0.683411906,1.328541571,0.895545097,DB0074110010774_,0.110322699,-0.0497736,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,hydrocortisone,DB00741
,7708,DB09020,10010774,103,1851,72,1532,0.311292697,1.183958189,0.860678989,1.635761206,0.478778733,DB0902010010774_,0.736516723,0.168863222,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,bisacodyl,DB09020
,7711,DB00451,10011469,114,47157,7,15412,6.58284213697657e-08,5.32252892,2.500416896,13.54279951,1.23858271703958e-06,DB0045110011469_,13.6015428,1.671948551,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,7715,DB00448,10011906,150,4995,122,3002,0.015636823,0.73898177,0.575385301,0.950506828,0.050937402,DB0044810011906_,2.977157819,-0.302482027,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,7716,DB00741,10011906,138,3956,133,3041,0.070382868,0.797634705,0.620950491,1.024867211,0.161962241,DB0074110011906_,1.820392052,-0.22610455,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,7717,DB09020,10011906,122,1832,120,1484,0.159878189,0.823593016,0.628721595,1.078961254,0.297304435,DB0902010011906_,1.212998631,-0.194078784,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,bisacodyl,DB09020
,7719,DB00448,10037660,119,5026,87,3037,0.190458289,0.826541116,0.619209072,1.106908045,0.337140287,DB0044810037660_,1.087256154,-0.190505616,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,7720,DB09020,10037660,55,1899,46,1558,0.919650526,0.980951937,0.64700993,1.493212494,0.964404362,DB0902010037660_,0.03624461,-0.019231815,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,bisacodyl,DB09020
,7723,DB00451,10040984,154,47117,57,15362,0.423362895,0.880864672,0.645711303,1.216376168,0.59219248,DB0045110040984_,0.523923561,-0.126851272,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,7733,DB00451,10061422,80,47191,40,15379,0.033196967,0.651782062,0.440385859,0.978446017,0.091715606,DB0045110061422_,2.389062734,-0.428045033,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,7740,DB00005,10008479,633,127449,172,42247,0.022034784,1.219921987,1.028759889,1.452949596,0.06671093,DB0000510008479_,2.707386473,0.198786912,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,7741,DB00005,10034972,80,128002,11,42408,0.003419325,2.409622631,1.276787607,5.019645211,0.015040908,DB0000510034972_,4.196981586,0.879470151,NA,10034972,Photosensitivity reaction,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,7743,DB00005,10037884,597,127485,143,42276,0.000396076,1.384411977,1.151295387,1.674038377,0.002541401,DB0000510037884_,5.975039684,0.325275484,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,7745,DB00682,10018867,51,19408,238,16126,7.2642071423936e-38,0.178074555,0.128816841,0.241998575,2.63365082396987e-35,DB0068210018867_,79.62210723,-1.725552967,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,warfarin,DB00682
,7746,DB00820,10038695,208,11707,101,5715,1,1.005338837,0.787144521,1.290933934,1,DB0082010038695_,0,0.005324636,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,7747,DB00555,10002855,203,6844,99,3387,0.950554533,1.014765143,0.791172714,1.308521563,0.988793395,DB0055510002855_,0.011269872,0.0146572,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,7748,DB00624,10002855,14,548,54,4342,0.031028572,2.053833944,1.046318078,3.779830415,0.086986563,DB0062410002855_,2.442001618,0.719708263,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,testosterone,DB00624
,7756,DB00065,10009900,201,9263,156,4801,0.000235563,0.667804517,0.537458902,0.831050007,0.001651362,DB0006510009900_,6.406155059,-0.403759788,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,infliximab,DB00065
,7757,DB00563,10009900,55,46591,42,15306,7.71633579958987e-05,0.430206193,0.282567562,0.659241222,0.000638112,DB0056310009900_,7.356996804,-0.843490666,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,7764,DB00451,10037377,289,46982,140,15279,0.000158949,0.671330624,0.546283411,0.828159233,0.001185577,DB0045110037377_,6.737526096,-0.39849353,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,7765,DB00999,10037377,131,21299,109,12130,0.003761521,0.684493032,0.526289457,0.891675623,0.016233127,DB0099910037377_,4.120701228,-0.379076814,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,7767,DB00412,10003119,20,1044,33,1353,0.483987106,0.785517238,0.424485977,1.419472814,0.648215366,DB0041210003119_,0.433532283,-0.241412876,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,7769,DB00115,10013573,706,17719,352,10120,0.043327733,1.145543397,1.004129,1.308548839,0.112330032,DB0011510013573_,2.186314027,0.135879107,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,7770,DB00169,10013573,1364,37327,524,17651,5.87506628601612e-05,1.23088253,1.11031678,1.366158912,0.00050698,DB0016910013573_,7.587038942,0.207731416,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,7771,DB00989,10013573,53,781,22,856,0.000126094,2.639014681,1.560823516,4.601237653,0.000972818,DB0098910013573_,6.935313557,0.970405621,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,rivastigmine,DB00989
,7772,DB01373,10013573,745,21975,211,7170,0.078781023,1.152022585,0.985044935,1.351951512,0.176279831,DB0137310013573_,1.735682595,0.141519167,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,calcium,DB01373
,7773,DB00989,10016173,64,770,79,799,0.33735432,0.840724005,0.58588557,1.202742166,0.506532521,DB0098910016173_,0.680166751,-0.173491848,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,rivastigmine,DB00989
,7774,DB01373,10016173,941,21779,229,7152,4.89198446444689e-05,1.34937124,1.163656045,1.56988716,0.000433898,DB0137310016173_,7.742699991,0.299638735,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,7775,DB00989,10028813,44,790,21,857,0.002188266,2.271892498,1.308868327,4.060275522,0.010471247,DB0098910028813_,4.559122164,0.820613184,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,rivastigmine,DB00989
,7776,DB01373,10028813,1227,21493,233,7148,4.97252363188002e-16,1.751383619,1.517146828,2.028603442,3.44407862092138e-14,DB0137310028813_,30.99953489,0.560406115,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,7778,DB00169,10031127,31,38660,50,18125,5.39035838978068e-08,0.290663082,0.179413499,0.464202865,1.03609192157503e-06,DB0016910031127_,13.78005469,-1.235590475,male,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,7781,DB08895,10013573,515,27599,84,6562,0.001131459,1.457684846,1.153514261,1.861486241,0.006099342,DB0889510013573_,5.099574435,0.376849455,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,7782,DB08895,10013946,263,27851,35,6611,0.000826832,1.783621267,1.248908733,2.618767798,0.004705702,DB0889510013946_,5.358980389,0.578645717,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,7783,DB08895,10019211,1707,26407,253,6393,6.21110084026465e-14,1.633365941,1.426267305,1.876635474,3.26844415588301e-12,DB0889510019211_,26.44670704,0.49064288,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,7792,DB00190,10010305,180,3117,382,4292,2.90935429939376e-06,0.648866819,0.537170626,0.781531553,3.68897143075566e-05,DB0019010010305_,10.20757779,-0.432527794,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,7793,DB00656,10010305,169,11844,141,6478,0.000315264,0.655544548,0.520012141,0.827486131,0.002101891,DB0065610010305_,6.164917973,-0.422289018,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,7794,DB00682,10010305,196,19263,161,16203,0.831126165,1.024006199,0.826154594,1.270680976,0.911697064,DB0068210010305_,0.09244751,0.023722581,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,7795,DB00843,10010305,88,2106,128,2045,0.004209117,0.667652644,0.499546242,0.889093916,0.017802983,DB0084310010305_,4.028389262,-0.403987234,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,donepezil,DB00843
,7796,DB00989,10010305,49,785,91,787,0.00076131,0.540027845,0.368172095,0.78429717,0.004387253,DB0098910010305_,5.429051983,-0.616134576,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,rivastigmine,DB00989
,7798,DB00264,10014625,110,29497,82,24810,0.425352446,1.128287524,0.839556585,1.521435638,0.594116908,DB0026410014625_,0.520679164,0.120701018,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,7799,DB00656,10014625,82,11931,32,6587,0.11580508,1.414708608,0.928552222,2.203013405,0.234907897,DB0065610014625_,1.44856177,0.346923579,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,7800,DB00682,10014625,41,19418,43,16321,0.325088711,0.801423706,0.509229167,1.259602142,0.493528749,DB0068210014625_,0.706174166,-0.221365501,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,7809,DB00190,10024264,36,3261,49,4625,0.911930185,1.042021709,0.656652262,1.639503657,0.96056931,DB0019010024264_,0.040229139,0.041162777,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,7810,DB00264,10024264,113,29494,118,24774,0.111995512,0.804382115,0.615553109,1.050690469,0.229080739,DB0026410024264_,1.473680764,-0.217680856,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,7811,DB00656,10024264,75,11938,57,6562,0.068249434,0.723293743,0.505008023,1.040731396,0.158132695,DB0065610024264_,1.844320754,-0.323939856,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,7812,DB00682,10024264,110,19349,91,16273,0.943450167,1.016624948,0.762426976,1.358348159,0.982297346,DB0068210024264_,0.01786122,0.016488266,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,7813,DB00843,10024264,36,2158,29,2144,0.453973777,1.233264547,0.732330631,2.093379615,0.62149483,DB0084310024264_,0.475627686,0.209664757,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,donepezil,DB00843
,7822,DB00264,10040741,48,29559,39,24853,0.914497187,1.034827017,0.663832582,1.622170739,0.961752398,DB0026410040741_,0.038998244,0.03423428,NA,10040741,Sinus bradycardia,10007541,Cardiac disorders,Card,metoprolol,DB00264
,7825,DB00843,10040741,38,2156,13,2160,0.000582187,2.927973877,1.520515824,6.007529907,0.003506194,DB0084310040741_,5.653224258,1.074310674,female,10040741,Sinus bradycardia,10007541,Cardiac disorders,Card,donepezil,DB00843
,7834,DB00264,10048294,152,29455,160,24732,0.05248838,0.797677872,0.634206751,1.00290897,0.129673111,DB0026410048294_,2.042738527,-0.226050432,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,7835,DB00656,10048294,80,11933,95,6524,4.2174038693735e-07,0.460408078,0.337099116,0.627532831,6.6320347416382e-06,DB0065610048294_,11.9235989,-0.775642057,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,7836,DB00682,10048294,87,19372,103,16261,0.019368309,0.709027277,0.526352116,0.95325713,0.060273012,DB0068210048294_,2.808870834,-0.34386128,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,7846,DB00656,10070863,679,11334,438,6181,0.008201426,0.845433445,0.745581185,0.959372291,0.030405821,DB0065610070863_,3.493121212,-0.16790583,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,7847,DB00682,10070863,185,19274,213,16151,0.001689161,0.727825296,0.593747386,0.891506989,0.008463334,DB0068210070863_,4.772012116,-0.317694238,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,7848,DB00843,10070863,63,2131,40,2133,0.027975535,1.576306379,1.038928337,2.416354956,0.0801763,DB0084310070863_,2.523527319,0.455084375,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,donepezil,DB00843
,7851,DB00515,10020772,45,1825,23,2128,0.001281584,2.280912972,1.345252698,3.965942916,0.006748084,DB0051510020772_,4.998496711,0.824575789,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,cisplatin,DB00515
,7859,DB00019,10006002,488,18524,148,9381,2.23095575628219e-08,1.669802959,1.384061778,2.024332013,4.62648300227829e-07,DB0001910006002_,14.58629868,0.512705631,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pegfilgrastim,DB00019
,7861,DB00531,10006002,97,7155,32,6484,1.76019821759929e-07,2.746622853,1.822118323,4.240413695,3.02397451958153e-06,DB0053110006002_,12.70893853,1.010372104,female,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclophosphamide,DB00531
,7862,DB01229,10006002,73,5668,14,2695,0.001089545,2.479050507,1.384190954,4.765899129,0.005911324,DB0122910006002_,5.130885452,0.907875627,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,paclitaxel,DB01229
,7867,DB00019,10016256,350,18662,155,9374,0.199049593,1.134221905,0.934565521,1.381660242,0.347896022,DB0001910016256_,1.05585163,0.12594687,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,7868,DB00227,10016256,187,2280,89,1714,0.000512747,1.579362903,1.21057304,2.072901184,0.00315154,DB0022710016256_,5.759863977,0.45702154,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lovastatin,DB00227
,7869,DB00227,10019211,117,2350,36,1767,1.04455474113353e-06,2.44321742,1.65934238,3.674963955,1.48733051845584e-05,DB0022710019211_,11.11594255,0.893315785,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lovastatin,DB00227
,7874,DB00019,10028411,78,18934,30,9499,0.260562304,1.304424055,0.845411067,2.060772034,0.422018608,DB0001910028411_,0.86270587,0.265761606,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pegfilgrastim,DB00019
,7875,DB00227,10028411,55,2412,26,1777,0.069148563,1.558316695,0.956351343,2.599808989,0.159801828,DB0022710028411_,1.833820805,0.443606197,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lovastatin,DB00227
,7876,DB00531,10028411,52,7200,22,6494,0.002298302,2.131683986,1.270559787,3.690281289,0.010889747,DB0053110028411_,4.519933618,0.756912271,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclophosphamide,DB00531
,7877,DB01229,10028411,60,5681,11,2698,0.002008263,2.590213598,1.346495253,5.473178994,0.009760945,DB0122910028411_,4.62936607,0.951740342,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,paclitaxel,DB01229
,7878,DB00019,10029331,80,18932,43,9486,0.702492902,0.932201533,0.63514936,1.384915442,0.821564909,DB0001910029331_,0.196544332,-0.07020625,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,pegfilgrastim,DB00019
,7879,DB00227,10029331,31,2436,20,1783,0.775791499,1.134435989,0.62402257,2.107555653,0.877822795,DB0022710029331_,0.130310533,0.126135601,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,lovastatin,DB00227
,7880,DB00531,10029331,175,7077,150,6366,0.69407777,1.049465818,0.836672084,1.317645777,0.815819199,DB0053110029331_,0.203562519,0.04828129,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,7881,DB01229,10029331,282,5459,81,2628,3.29742905647971e-05,1.675915544,1.298499593,2.182823507,0.000308225,DB0122910029331_,8.084679914,0.516359609,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,paclitaxel,DB01229
,7882,DB00019,10029366,124,18888,45,9484,0.071523977,1.383606356,0.97541627,1.993771421,0.163913662,DB0001910029366_,1.808415442,0.324693392,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,pegfilgrastim,DB00019
,7884,DB00531,10029366,157,7095,168,6348,0.115556954,0.836144819,0.666526164,1.048507587,0.23454033,DB0053110029366_,1.450127724,-0.178953453,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,cyclophosphamide,DB00531
,7885,DB01229,10029366,199,5542,36,2673,4.0495952614952e-09,2.665883728,1.855656902,3.927569202,9.9248122562612e-08,DB0122910029366_,16.12564283,0.980535608,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,paclitaxel,DB01229
,7886,DB00019,10037660,188,18824,118,9411,0.058729333,0.796552119,0.628533235,1.012810416,0.141125431,DB0001910037660_,1.958106206,-0.227462717,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,7888,DB00531,10037660,433,6819,521,5995,3.40175875868773e-06,0.73068803,0.638687037,0.835599535,4.21497371564887e-05,DB0053110037660_,10.07428211,-0.313768682,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,7889,DB01229,10037660,222,5519,140,2569,0.006769095,0.738127067,0.59151852,0.923544912,0.026094546,DB0122910037660_,3.646028965,-0.303639292,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,7894,DB00051,10022052,204,25527,40,11380,4.18063719700428e-07,2.273550402,1.61219198,3.278596289,6.58603828128604e-06,DB0005110022052_,11.93055856,0.821342663,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,7903,DB00099,10011906,220,2165,190,1765,0.602069441,0.94400106,0.765865592,1.164309839,0.746216917,DB0009910011906_,0.292738947,-0.05762799,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,filgrastim,DB00099
,7904,DB00115,10011906,526,17899,601,9871,1.04359758989141e-32,0.482665955,0.427449712,0.544938424,2.74309626502957e-30,DB0011510011906_,68.06846548,-0.728430468,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,7905,DB00588,10011906,416,16108,370,8098,9.54717751455223e-15,0.56522597,0.488881551,0.653691272,5.64550699632609e-13,DB0058810011906_,28.2027462,-0.570529681,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,7906,DB00814,10011906,141,8146,122,3293,2.47217102467832e-09,0.467228285,0.362766336,0.602496592,6.34270525950899e-08,DB0081410011906_,16.57337537,-0.760937308,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,7907,DB00924,10011906,352,9810,247,4004,3.98426966062371e-10,0.581702255,0.49080697,0.690165232,1.19075074507668e-08,DB0092410011906_,18.24609676,-0.541796552,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,7908,DB01041,10011906,250,2795,375,2743,7.44122316965453e-07,0.654313867,0.550472928,0.77675207,1.10224035511056e-05,DB0104110011906_,11.41558067,-0.424168123,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,thalidomide,DB01041
,7909,DB01137,10011906,285,7487,310,5283,3.08763122404243e-07,0.648754771,0.548219693,0.767449461,5.01441993969449e-06,DB0113710011906_,12.20319281,-0.43270049,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,7913,DB00112,10011906,1750,4183,1350,2741,0.000202546,0.849444398,0.778904924,0.926442281,0.001456814,DB0011210011906_,6.531503709,-0.163172792,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,7914,DB00526,10011906,154,1444,179,1715,0.862420823,1.021796493,0.808956153,1.289546811,0.936124851,DB0052610011906_,0.066006423,0.021562346,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,oxaliplatin,DB00526
,7915,DB01101,10011906,780,6809,493,3415,0.00018691,0.793549869,0.702678508,0.896682653,0.001362812,DB0110110011906_,6.598205361,-0.231238894,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,7916,DB00112,10018001,83,5850,54,4037,0.793090246,1.060690025,0.742128749,1.52689353,0.887854389,DB0011210018001_,0.118947526,0.058919664,NA,10018001,Gastrointestinal perforation,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,7919,DB00175,10013709,318,7813,236,5870,0.895599001,1.012360703,0.849765024,1.207369654,0.95615204,DB0017510013709_,0.044838341,0.012284933,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,7920,DB00697,10013709,346,5750,95,1711,0.52136031,1.083752466,0.855375801,1.38367282,0.680181449,DB0069710013709_,0.38539568,0.080429525,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,7921,DB00863,10013709,449,10224,212,5628,0.074186013,1.165872442,0.984647361,1.383753188,0.168508412,DB0086310013709_,1.780769605,0.153469684,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,7922,DB01136,10013709,293,9591,324,10791,0.837931016,1.017469496,0.863637851,1.198313495,0.916610526,DB0113610013709_,0.087072624,0.017318659,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,7923,DB06228,10013709,293,15619,230,15846,0.004121402,1.292413279,1.082169361,1.545014724,0.01750239,DB0622810013709_,4.045417835,0.256511229,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,7924,DB00381,10013968,1606,27754,903,21984,3.94365162298576e-16,1.408754387,1.295076857,1.533067875,2.7568851837814e-14,DB0038110013968_,31.22208982,0.3427059,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,7925,DB00697,10013968,237,5859,45,1761,0.004736717,1.582833431,1.141197206,2.238430385,0.019579999,DB0069710013968_,3.933246717,0.459216552,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tizanidine,DB00697
,7926,DB00863,10013968,551,10122,266,5574,0.091198565,1.140713266,0.979920008,1.330357401,0.197166827,DB0086310013968_,1.623705071,0.131653739,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,7927,DB01136,10013968,661,9223,581,10534,8.2428786956471e-06,1.299387031,1.156463784,1.460298968,9.1826262562019e-05,DB0113610013968_,9.295612217,0.261892639,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,7928,DB06228,10013968,703,15209,406,15670,1.6142223062973e-20,1.783965294,1.573276462,2.025016171,1.76960758143759e-18,DB0622810013968_,40.87577386,0.57883858,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,7929,DB00175,10033425,240,7891,98,6008,1.08792595046683e-07,1.864496479,1.464394271,2.389062941,1.9579687509771e-06,DB0017510033425_,13.14360297,0.622991032,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,7930,DB00381,10033425,811,28549,372,22515,1.52864445968808e-18,1.719307842,1.516936452,1.951570396,1.38314697497078e-16,DB0038110033425_,36.51700017,0.541921792,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,7931,DB00697,10033425,180,5916,44,1762,0.259376453,1.218387394,0.867860308,1.742723784,0.42048292,DB0069710033425_,0.866351418,0.197528176,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,tizanidine,DB00697
,7932,DB01136,10033425,256,9628,151,10964,1.01615252026531e-10,1.930535687,1.569701878,2.381239256,3.3138423070935e-09,DB0113610033425_,19.5251575,0.657797523,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,carvedilol,DB01136
,7933,DB06228,10033425,258,15654,145,15931,6.77456637570687e-09,1.810750034,1.469913989,2.237696822,1.57723186169579e-07,DB0622810033425_,15.66242433,0.593741143,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,rivaroxaban,DB06228
,7934,DB00175,10043607,61,8070,51,6055,0.567019873,0.897437303,0.607571734,1.330391779,0.718223154,DB0017510043607_,0.330974958,-0.108212018,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,pravastatin,DB00175
,7935,DB00316,10043607,461,65013,318,36635,0.006233618,0.816914613,0.706161684,0.945916867,0.024398876,DB0031610043607_,3.713218205,-0.202220702,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,7936,DB00697,10043607,51,6045,18,1788,0.564199343,0.838047977,0.47989721,1.528351566,0.716026349,DB0069710043607_,0.334038313,-0.176679928,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,tizanidine,DB00697
,7937,DB00863,10043607,64,10609,41,5799,0.473597585,0.853262787,0.566842259,1.297247946,0.63951671,DB0086310043607_,0.447042528,-0.158687705,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,ranitidine,DB00863
,7938,DB01136,10043607,90,9794,71,11044,0.026349894,1.429353732,1.03423808,1.98187594,0.076525396,DB0113610043607_,2.570132618,0.357222406,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,carvedilol,DB01136
,7939,DB06228,10043607,340,15572,354,15722,0.70123139,0.969697909,0.831706846,1.130402839,0.820543431,DB0622810043607_,0.197788438,-0.03077069,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,rivaroxaban,DB06228
,7940,DB00175,10048959,189,7942,103,6003,0.008481466,1.386924433,1.082525209,1.785072014,0.031212508,DB0017510048959_,3.466936364,0.327088658,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,7941,DB00316,10048959,1190,64284,487,36466,8.40438461028211e-10,1.38612327,1.245369963,1.544602117,2.3722066928182e-08,DB0031610048959_,17.55686013,0.326510837,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,7942,DB00381,10048959,833,28527,430,22457,9.27242890690436e-13,1.52499312,1.353965013,1.719523023,4.17544629491325e-11,DB0038110048959_,23.89921477,0.421989899,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,7943,DB00697,10048959,128,5968,28,1778,0.149309057,1.361865943,0.895659557,2.13739851,0.283016411,DB0069710048959_,1.262250394,0.308855777,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,7944,DB00863,10048959,209,10464,83,5757,0.013366458,1.385346796,1.06697986,1.812489166,0.044867806,DB0086310048959_,3.104034766,0.325950503,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,7945,DB01136,10048959,230,9654,174,10941,6.72316379641088e-05,1.498014034,1.222477954,1.838360183,0.000567587,DB0113610048959_,7.474115679,0.404140254,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,7946,DB06228,10048959,208,15704,161,15915,0.011860345,1.309268596,1.05937433,1.620532449,0.040796855,DB0622810048959_,3.199150288,0.269468658,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,7948,DB00215,10003549,300,10803,141,5135,0.958811675,1.011341829,0.822797506,1.247879811,0.996475689,DB0021510003549_,0.003530536,0.011277993,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,7949,DB00264,10003549,997,28610,893,23999,0.165604975,0.936544032,0.853386299,1.027877928,0.304944255,DB0026410003549_,1.187626291,-0.065558741,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,7950,DB00268,10003549,98,2877,69,1476,0.055558486,0.728680426,0.526492228,1.013196118,0.135274401,DB0026810003549_,2.000449964,-0.316520016,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,7951,DB00390,10003549,204,3941,152,3149,0.54778655,1.072401481,0.860284098,1.338990673,0.702363754,DB0039010003549_,0.353303841,0.069900508,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,7952,DB14726,10003549,56,1961,59,2789,0.125186549,1.349812139,0.915000816,1.98931391,0.248874323,DB1472610003549_,1.390807236,0.299965427,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,dabigatran,DB14726
,7953,DB00215,10003658,65,11038,53,5223,0.003994099,0.580329351,0.39695133,0.851849863,0.017061003,DB0021510003658_,4.07095992,-0.544159489,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,citalopram,DB00215
,7955,DB00390,10003658,168,3977,146,3155,0.450688744,0.912863471,0.723202859,1.153321481,0.618398434,DB0039010003658_,0.480622313,-0.091168949,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,digoxin,DB00390
,7956,DB00996,10003658,194,38759,202,22223,4.79626452846101e-09,0.550688585,0.449511786,0.674427569,1.15681958487634e-07,DB0099610003658_,15.97242115,-0.59658581,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,gabapentin,DB00996
,7957,DB14726,10003658,75,1942,96,2752,0.527955541,1.107081313,0.80264772,1.52227019,0.685443898,DB1472610003658_,0.377688624,0.101727104,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,dabigatran,DB14726
,7965,DB00264,10016100,63,29544,56,24836,0.782760182,0.945695477,0.64903089,1.381152633,0.881806742,DB0026410016100_,0.12578236,-0.055834668,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,7968,DB00996,10016100,41,38912,36,22389,0.075040085,0.655321884,0.408390932,1.055625014,0.169897811,DB0099610016100_,1.772558132,-0.422628738,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,7971,DB00264,10018830,35,29572,40,24852,0.202363208,0.735350604,0.453358709,1.187757939,0.35175855,DB0026410018830_,1.044810276,-0.307407881,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,7974,DB00996,10018830,36,38917,31,22394,0.100396217,0.668273582,0.40175866,1.117472077,0.211426075,DB0099610018830_,1.553879868,-0.403057636,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,7979,DB00996,10018836,66,38887,46,22379,0.326966521,0.825712218,0.557948251,1.231058708,0.495363844,DB0099610018836_,0.702462748,-0.191508971,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,7980,DB14726,10018836,34,1983,44,2804,0.728854729,1.092630174,0.67461118,1.756074271,0.841941003,DB1472610018836_,0.172045335,0.088587794,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,dabigatran,DB14726
,7981,DB00215,10019063,77,11026,70,5206,0.000119829,0.519374286,0.370169063,0.729767132,0.000930349,DB0021510019063_,6.979950904,-0.655130488,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,7982,DB00264,10019063,141,29466,155,24737,0.022402353,0.763691746,0.603171762,0.966244486,0.06750884,DB0026410019063_,2.695496725,-0.269591045,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,7983,DB00268,10019063,62,2913,101,1444,1.96763135230555e-13,0.304383909,0.216772316,0.424595143,9.71252396156834e-12,DB0026810019063_,25.35760493,-1.189465514,male,10019063,Hallucination,10037175,Psychiatric disorders,Psych,ropinirole,DB00268
,7985,DB00996,10019063,214,38739,186,22239,4.5888327438382e-05,0.660525507,0.539734128,0.808841669,0.000410511,DB0099610019063_,7.798107971,-0.414719538,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,7988,DB00264,10027141,45,29562,44,24848,0.523220869,0.859645622,0.554376707,1.333770535,0.681574891,DB0026410027141_,0.383349143,-0.151235042,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,7992,DB14726,10027141,17,2000,40,2808,0.079266774,0.59676127,0.316263045,1.080417659,0.177185195,DB1472610027141_,1.730559793,-0.516238128,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,dabigatran,DB14726
,7994,DB00264,10042604,57,29550,47,24845,1,1.019668821,0.680558758,1.53420517,1,DB0026410042604_,0,0.019477889,NA,10042604,Supraventricular tachycardia,10007541,Cardiac disorders,Card,metoprolol,DB00264
,7999,DB00215,10048294,44,11059,37,5239,0.011943861,0.563406281,0.355086292,0.898325995,0.041003641,DB0021510048294_,3.194094401,-0.573754276,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,8002,DB00996,10048294,229,38724,207,22218,3.15464870726197e-06,0.634765917,0.523265796,0.770306233,3.95421751408588e-05,DB0099610048294_,10.13814273,-0.454498983,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,8005,DB00264,10049438,69,29538,55,24837,0.787280717,1.05489541,0.729123536,1.532467121,0.884742027,DB0026410049438_,0.122459171,0.053441625,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,8008,DB00996,10049438,75,38878,42,22383,0.923698343,1.028079411,0.695253826,1.538354038,0.966829343,DB0099610049438_,0.03373328,0.027692412,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,8015,DB00471,10002855,278,13911,79,5386,0.016947447,1.362405221,1.05534263,1.775820343,0.054252057,DB0047110002855_,2.914114377,0.309251683,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,montelukast,DB00471
,8016,DB00588,10002855,361,16163,124,8344,8.34473509655223e-05,1.502903772,1.220015798,1.861530349,0.000683413,DB0058810002855_,7.28841138,0.407399085,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,8017,DB00983,10002855,59,3442,21,1719,0.231129442,1.403044082,0.836710876,2.43961632,0.387278472,DB0098310002855_,0.948611279,0.338644221,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,formoterol,DB00983
,8018,DB01222,10002855,148,9126,53,5352,0.001917249,1.637599402,1.186710924,2.289994674,0.00940203,DB0122210002855_,4.666829686,0.49323139,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,budesonide,DB01222
,8019,DB01409,10002855,115,5916,38,3928,0.000117444,2.009223505,1.377952334,2.987701743,0.000915623,DB0140910002855_,6.995905352,0.697748331,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,tiotropium,DB01409
,8020,DB00471,10003553,488,13701,152,5313,0.019666665,1.244952206,1.032672135,1.507810331,0.060999268,DB0047110003553_,2.79689341,0.21909714,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,8021,DB00588,10003553,478,16046,137,8331,2.42547305650575e-10,1.811457484,1.492132342,2.210861827,7.46149145397647e-09,DB0058810003553_,18.71351052,0.594131761,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,8022,DB00983,10003553,162,3339,48,1692,0.000969746,1.71008285,1.224988486,2.425168356,0.005371355,DB0098310003553_,5.226674986,0.53654182,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,formoterol,DB00983
,8023,DB01409,10003553,160,5871,45,3921,6.85168011750346e-08,2.37441219,1.691627155,3.391832993,1.2854847386765e-06,DB0140910003553_,13.56437468,0.864749908,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,8029,DB00471,10010264,261,13928,78,5387,0.050217338,1.29416716,0.999243301,1.692217292,0.125422604,DB0047110010264_,2.076066408,0.257867369,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,8030,DB01222,10010264,206,9068,101,5304,0.151845008,1.193020546,0.933342599,1.532901142,0.286501044,DB0122210010264_,1.250013098,0.176488365,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,8031,DB01409,10010264,109,5922,56,3910,0.148460648,1.285097437,0.920224507,1.811766665,0.281875768,DB0140910010264_,1.266288845,0.250834542,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,8032,DB00471,10013709,639,13550,217,5248,0.109712032,1.140488693,0.972842753,1.341048631,0.225621465,DB0047110013709_,1.488896618,0.131456848,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,8033,DB00983,10013709,143,3358,57,1683,0.168100869,1.257365918,0.913203136,1.75071463,0.308283988,DB0098310013709_,1.176733883,0.229018992,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,formoterol,DB00983
,8034,DB01222,10013709,433,8841,207,5198,0.016875114,1.229802853,1.035912618,1.463698136,0.054089673,DB0122210013709_,2.917112006,0.206853874,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,8035,DB01409,10013709,303,5728,169,3797,0.082714261,1.188443574,0.97679864,1.449768427,0.182924097,DB0140910013709_,1.698683985,0.17264453,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,8046,DB00471,10043071,77,14112,15,5450,0.013803154,1.982427495,1.129310357,3.715635436,0.046028024,DB0047110043071_,3.078504852,0.684322101,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,montelukast,DB00471
,8047,DB00588,10043071,98,16426,36,8432,0.099117679,1.39738748,0.943825808,2.110472855,0.209509791,DB0058810043071_,1.562984808,0.334604407,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,fluticasone propionate,DB00588
,8049,DB01222,10043071,58,9216,26,5379,0.307425616,1.301985615,0.805514732,2.157438653,0.474552638,DB0122210043071_,0.745382734,0.263890496,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,budesonide,DB01222
,8050,DB01409,10043071,36,5995,23,3943,1,1.029465613,0.592590318,1.82255587,1,DB0140910043071_,0,0.029039846,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,tiotropium,DB01409
,8051,DB00471,10044565,128,14061,35,5430,0.078770338,1.412223606,0.963743852,2.118535312,0.176263427,DB0047110044565_,1.735775659,0.345165488,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,8052,DB00588,10044565,170,16354,93,8375,0.601073906,0.936113288,0.721720256,1.220469071,0.745334479,DB0058810044565_,0.293922197,-0.066018775,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,8053,DB01409,10044565,62,5969,27,3939,0.081274473,1.515286848,0.947980131,2.481994389,0.180523429,DB0140910044565_,1.711894708,0.41560476,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,tiotropium,DB01409
,8054,DB00471,10047924,210,13979,64,5401,0.103269561,1.267727276,0.952213119,1.707640684,0.215945936,DB0047110047924_,1.532727199,0.237225751,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,8055,DB00588,10047924,241,16283,76,8392,0.000127857,1.634280417,1.256026422,2.146921719,0.000983958,DB0058810047924_,6.923927299,0.491202595,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,8056,DB00983,10047924,98,3403,38,1702,0.197548041,1.289830392,0.87407207,1.937642829,0.346031604,DB0098310047924_,1.061225168,0.25451073,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,formoterol,DB00983
,8057,DB01222,10047924,147,9127,63,5342,0.043389188,1.365663651,1.007879229,1.868662333,0.112433404,DB0122210047924_,2.185394201,0.311640502,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,8058,DB01409,10047924,109,5922,38,3928,0.000469045,1.90247486,1.300925178,2.836206438,0.00292777,DB0140910047924_,5.83351435,0.643155597,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,8068,DB06228,10044390,79,15833,88,15988,0.535836977,0.906527401,0.659871451,1.243563622,0.692321422,DB0622810044390_,0.367704949,-0.098134022,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,8074,DB00108,10037087,92,10102,17,3278,0.032919081,1.755924369,1.037411494,3.148596485,0.091105874,DB0010810037087_,2.395732999,0.562995424,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,natalizumab,DB00108
,8075,DB00108,10061623,49,10145,7,3288,0.041562388,2.268445309,1.020826474,5.942529084,0.108865706,DB0010810061623_,2.217640208,0.819094711,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,8076,DB00108,10012735,95,10099,22,3273,0.193974257,1.399430918,0.871302497,2.341816037,0.341684315,DB0010810012735_,1.073868024,0.336065667,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,natalizumab,DB00108
,8077,DB00108,10013968,130,10064,44,3251,0.790113076,0.954414312,0.671573021,1.379139577,0.886276712,DB0010810013968_,0.120726061,-0.046657412,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,natalizumab,DB00108
,8078,DB00108,10020751,250,9944,37,3258,1.3670511686498e-06,2.213756051,1.558825585,3.224732987,1.89619735978681e-05,DB0010810020751_,10.87307497,0.794690643,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,natalizumab,DB00108
,8079,DB00108,10037844,103,10091,37,3258,0.554611092,0.89877257,0.610410172,1.349378662,0.70812299,DB0010810037844_,0.345137486,-0.106725257,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,natalizumab,DB00108
,8080,DB00005,10050584,1281,126801,252,42167,1.38970931707829e-15,1.690356551,1.475027745,1.943515487,9.18956211305729e-14,DB0000510050584_,30.01812301,0.524939483,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,8081,DB01268,10012735,444,1699,603,2527,0.193745783,1.095139592,0.952280949,1.258870922,0.341384811,DB0126810012735_,1.07474496,0.090881837,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,8082,DB00177,10003549,156,4644,93,2757,1,0.995832418,0.761915592,1.307457308,1,DB0017710003549_,0,-0.00417629,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,8083,DB00213,10003549,632,18263,430,12991,0.506149462,1.04549299,0.921501254,1.187023342,0.666991131,DB0021310003549_,0.404978529,0.044488535,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,8084,DB00404,10003549,593,19299,235,9627,0.00308038,1.258799005,1.078174782,1.473301684,0.013828577,DB0040410003549_,4.281018006,0.230158096,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,8085,DB00476,10003549,481,16776,199,5978,0.084922226,0.861334113,0.726643702,1.023982463,0.186660595,DB0047610003549_,1.678463313,-0.149272797,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,8086,DB00484,10003549,60,2447,46,1734,0.691018489,0.924308281,0.615752978,1.395344573,0.813682203,DB0048410003549_,0.206185403,-0.078709625,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,brimonidine,DB00484
,8087,DB00654,10003549,89,3727,68,2530,0.510365991,0.888487335,0.637929827,1.242093315,0.670784562,DB0065410003549_,0.399307264,-0.118234886,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,8088,DB00761,10003549,602,14705,362,8263,0.320865547,0.934463321,0.816532684,1.070554729,0.48913286,DB0076110003549_,0.71512113,-0.067782903,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,8089,DB00814,10003549,199,8088,87,3328,0.645076804,0.941193434,0.725502323,1.229318283,0.780833021,DB0081410003549_,0.247393954,-0.060606599,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,8091,DB00999,10003549,654,20776,336,11903,0.114970241,1.115163408,0.974251704,1.278263727,0.233583983,DB0099910003549_,1.454213596,0.109000949,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,8092,DB01060,10003549,180,8407,134,4947,0.044523851,0.790466431,0.626749989,0.99894854,0.114625557,DB0106010003549_,2.166084487,-0.235132089,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,8093,DB01076,10003549,781,24966,823,24760,0.233242118,0.941113216,0.85090057,1.040896418,0.389824446,DB0107610003549_,0.94205878,-0.060691832,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,8094,DB01118,10003549,121,2942,192,4517,0.813428529,0.967591846,0.760507218,1.227248318,0.899777755,DB0111810003549_,0.105607485,-0.032944927,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,8096,DB01377,10003549,159,3637,90,2580,0.100746918,1.253187136,0.956648801,1.64992531,0.212011749,DB0137710003549_,1.551113588,0.225690015,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,8097,DB04861,10003549,71,1894,46,1341,0.702628285,1.092816186,0.738302981,1.631080243,0.821592063,DB0486110003549_,0.196511281,0.088758021,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,nebivolol,DB04861
,8098,DB06605,10003549,403,13670,350,12683,0.3750039,1.068317464,0.921512122,1.238865219,0.54481791,DB0660510003549_,0.607303651,0.066084947,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,8099,DB09020,10003549,96,1858,67,1537,0.333615033,1.185233051,0.851874241,1.656894818,0.502698415,DB0902010003549_,0.687764861,0.169939423,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,bisacodyl,DB09020
,8100,DB09104,10003549,52,998,31,841,0.1437521,1.413284169,0.879746137,2.304183642,0.275151936,DB0910410003549_,1.290431841,0.345916194,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,magnesium hydroxide,DB09104
,8101,DB13867,10003549,125,4425,75,2479,0.654184041,0.933719917,0.692587669,1.265929625,0.78801281,DB1386710003549_,0.238240934,-0.06857876,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,8102,DB00177,10008190,53,4747,39,2811,0.329231771,0.804769478,0.520745047,1.253302352,0.497877462,DB0017710008190_,0.697401293,-0.217199405,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,valsartan,DB00177
,8103,DB00404,10008190,144,19748,74,9788,0.828554073,0.964521889,0.722957921,1.295881185,0.909895047,DB0040410008190_,0.09442602,-0.036122752,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,8104,DB00451,10008190,368,46903,203,15216,5.07319565193272e-09,0.588106896,0.493644425,0.70222777,1.2155783747589e-07,DB0045110008190_,15.92287566,-0.530846552,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,8105,DB00476,10008190,110,17147,47,6130,0.317556268,0.836730231,0.588686845,1.205449588,0.485429863,DB0047610008190_,0.722720464,-0.178253566,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,8107,DB00654,10008190,33,3783,17,2581,0.387678789,1.32433547,0.71502351,2.54086946,0.557691384,DB0065410008190_,0.583949545,0.280910802,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,latanoprost,DB00654
,8108,DB00814,10008190,35,8252,26,3389,0.023924625,0.552904013,0.32288301,0.958031962,0.071065518,DB0081410008190_,2.644153034,-0.592570867,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,8110,DB01060,10008190,56,8531,28,5053,0.498584874,1.18464414,0.738764951,1.939618206,0.66043306,DB0106010008190_,0.414859508,0.169442426,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,amoxicillin,DB01060
,8111,DB01076,10008190,429,25318,383,25200,0.128271743,1.114881129,0.967987818,1.284411774,0.253181855,DB0107610008190_,1.373647253,0.108747789,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,8112,DB01118,10008190,28,3035,49,4660,0.640038991,0.877371909,0.529685117,1.427537755,0.777063504,DB0111810008190_,0.252233202,-0.130824307,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,amiodarone,DB01118
,8114,DB01377,10008190,39,3757,38,2632,0.162696917,0.719044291,0.44666072,1.158411351,0.300970403,DB0137710008190_,1.200743346,-0.329832322,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,magnesium oxide,DB01377
,8116,DB06605,10008190,439,13634,385,12648,0.436173947,1.057814691,0.918372417,1.218747807,0.604751212,DB0660510008190_,0.502938126,0.056205168,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,8117,DB09020,10008190,31,1923,19,1585,0.321164807,1.344689364,0.732775712,2.529823976,0.489451628,DB0902010008190_,0.714469641,0.29616303,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,bisacodyl,DB09020
,8119,DB13867,10008190,33,4517,30,2524,0.064108708,0.614671402,0.362498402,1.046140068,0.150845707,DB1386710008190_,1.891497769,-0.486667459,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,fluticasone,DB13867
,8120,DB01222,10060933,39,9235,15,5390,0.203273443,1.517446901,0.81694641,2.966060494,0.352972632,DB0122210060933_,1.041364754,0.417029252,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,8122,DB01080,10022437,45,2014,45,2067,0.915541182,1.026314986,0.660397264,1.59497942,0.962157407,DB0108010022437_,0.038577217,0.025974704,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,vigabatrin,DB01080
,8124,DB06218,10022437,32,1662,24,1412,0.686456987,1.132715748,0.643166004,2.019975884,0.810835479,DB0621810022437_,0.209690107,0.124618066,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,lacosamide,DB06218
,8126,DB01080,10022998,44,2015,35,2077,0.258822768,1.295739588,0.808616155,2.090220248,0.419934969,DB0108010022998_,0.867655416,0.259081643,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,vigabatrin,DB01080
,8130,DB01080,10047700,69,1990,54,2058,0.143069736,1.32134726,0.906855492,1.93374291,0.274143086,DB0108010047700_,1.294105099,0.278651867,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,vigabatrin,DB01080
,8132,DB06218,10047700,42,1652,25,1411,0.173405399,1.434749912,0.849502492,2.469701486,0.315418908,DB0621810047700_,1.153853658,0.360990557,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lacosamide,DB06218
,8145,DB05812,10013968,8,174,170,7783,0.063202351,2.104629469,0.880138698,4.335160846,0.14931456,DB0581210013968_,1.901700057,0.744139427,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,abiraterone,DB05812
,8146,DB06605,10016173,536,13537,429,12604,0.02168473,1.163297296,1.020240877,1.327017234,0.065920675,DB0660510016173_,2.719303153,0.15125847,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,8147,DB06605,10042316,43,14030,45,12988,0.594138399,0.884591663,0.568207155,1.37549832,0.740138759,DB0660510042316_,0.300917599,-0.122629138,NA,10042316,Subarachnoid haemorrhage,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,8150,DB00230,10047513,347,19327,107,8544,0.000994475,1.433659198,1.14924876,1.800534452,0.00547487,DB0023010047513_,5.207586809,0.360230055,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,pregabalin,DB00230
,8151,DB00921,10013654,222,5623,348,4555,3.62694767870755e-14,0.516806063,0.432758273,0.616203802,1.96971734989314e-12,DB0092110013654_,26.95313106,-0.660087595,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,8154,DB00188,10035226,464,7422,542,8286,0.494082435,0.955737322,0.839140235,1.088260719,0.656731731,DB0018810035226_,0.420479668,-0.045272171,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,bortezomib,DB00188
,8155,DB00213,10002198,55,18840,20,13401,0.009499617,1.956042728,1.153146829,3.44703615,0.034170023,DB0021310002198_,3.376406541,0.670923416,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,pantoprazole,DB00213
,8156,DB00451,10002198,109,47162,15,15404,0.000760641,2.373524381,1.377006019,4.387044734,0.004384528,DB0045110002198_,5.429673259,0.864375931,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,levothyroxine,DB00451
,8158,DB00213,10013950,167,18728,80,13341,0.003474165,1.48702369,1.131374188,1.968183815,0.015229893,DB0021310013950_,4.184495138,0.396776599,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,8160,DB00203,10069802,41,13837,12,8926,0.01582985,2.20395411,1.135608154,4.609136998,0.051422801,DB0020310069802_,2.967673599,0.79025307,NA,10069802,Device related sepsis,10021881,Infections and infestations,Infec,sildenafil,DB00203
,8161,DB00374,10069802,82,17634,18,5706,0.16097232,1.474030972,0.876243505,2.612079347,0.298789453,DB0037410069802_,1.208016125,0.388000806,NA,10069802,Device related sepsis,10021881,Infections and infestations,Infec,treprostinil,DB00374
,8165,DB00338,10030963,36,33638,23,22249,1,1.035275447,0.596756453,1.830380283,1,DB0033810030963_,0,0.034667523,NA,10030963,Oral candidiasis,10021881,Infections and infestations,Infec,omeprazole,DB00338
,8170,DB00051,10053762,345,25386,135,11285,0.232071286,1.136028016,0.927228373,1.398410103,0.388434873,DB0005110053762_,0.94562976,0.127537982,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,8171,DB00455,10053762,275,9126,135,4983,0.345267357,1.112274348,0.899218327,1.38113698,0.514705002,DB0045510053762_,0.664161354,0.106406882,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,8172,DB00641,10053762,325,13799,246,12229,0.068306906,1.17081626,0.987198071,1.390016754,0.15823796,DB0064110053762_,1.8436553,0.157701164,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,8174,DB01222,10005557,60,9214,35,5370,1,0.999100788,0.646903627,1.564412616,1,DB0122210005557_,0,-0.000899616,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,budesonide,DB01222
,8178,DB00316,10064658,43,65431,32,36921,0.231822109,0.758264627,0.468659141,1.238338141,0.388116177,DB0031610064658_,0.946450559,-0.276722842,NA,10064658,Osteonecrosis of jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,8183,DB00175,10003549,254,7877,209,5897,0.339742188,0.909831552,0.752219008,1.101427648,0.508838941,DB0017510003549_,0.675623735,-0.094495804,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,8184,DB00338,10003549,1083,32591,717,21555,0.980481897,0.99898655,0.906706893,1.101116434,1,DB0033810003549_,0,-0.001013964,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,8185,DB00678,10003549,506,15093,339,10385,0.722063865,1.027027832,0.89117493,1.184693496,0.836264841,DB0067810003549_,0.178809921,0.026669031,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,8186,DB00788,10003549,228,9128,120,4941,0.820407832,1.028471965,0.818587321,1.297421724,0.90434181,DB0078810003549_,0.100547881,0.028074172,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,8187,DB00829,10003549,187,7865,83,4371,0.094968585,1.252130321,0.959119697,1.646192689,0.203153551,DB0082910003549_,1.593793178,0.224846357,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,8188,DB01050,10003549,420,17688,220,9151,0.89930068,0.987676294,0.835317579,1.170367149,0.956490275,DB0105010003549_,0.044484657,-0.012400272,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,8189,DB05259,10003549,219,11051,61,2667,0.322272866,0.866417316,0.647411296,1.174285241,0.490614056,DB0525910003549_,0.712097498,-0.143388597,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,8190,DB08908,10003549,270,10403,93,3186,0.346752933,0.889128464,0.69747464,1.141815844,0.51617731,DB0890810003549_,0.661304949,-0.11751355,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,8191,DB00175,10012174,127,8004,98,6008,0.838932719,0.972739519,0.739840598,1.282157278,0.917410875,DB0017510012174_,0.086199842,-0.027638942,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,pravastatin,DB00175
,8192,DB00476,10012174,167,17090,63,6114,0.707400991,0.948328074,0.70459015,1.290145918,0.825089674,DB0047610012174_,0.192263203,-0.053054767,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,duloxetine,DB00476
,8193,DB00557,10012174,74,5913,32,3035,0.47044594,1.186907602,0.772127743,1.86197497,0.63671652,DB0055710012174_,0.451430747,0.171351271,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,hydroxyzine,DB00557
,8194,DB00678,10012174,211,15388,141,10583,0.827168893,1.02917793,0.826395888,1.284840567,0.908952105,DB0067810012174_,0.095462876,0.028760358,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,8195,DB00788,10012174,103,9253,54,5007,0.933028222,1.0321388,0.734108303,1.465341192,0.973721907,DB0078810012174_,0.026629532,0.031633154,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,naproxen,DB00788
,8196,DB00829,10012174,73,7979,37,4417,0.690502181,1.092196929,0.724353493,1.671920487,0.813292847,DB0082910012174_,0.206664029,0.088191199,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,diazepam,DB00829
,8197,DB01050,10012174,172,17936,105,9266,0.181422865,0.846278958,0.659144069,1.090776492,0.325648806,DB0105010012174_,1.12193576,-0.166906236,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ibuprofen,DB01050
,8198,DB05259,10012174,45,11225,8,2720,0.490611487,1.36299616,0.634905065,3.351866913,0.653858433,DB0525910012174_,0.424864415,0.309685335,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,glatiramer,DB05259
,8199,DB08908,10012174,147,10526,35,3244,0.187139808,1.294362345,0.888073731,1.933081539,0.332925202,DB0890810012174_,1.099837434,0.258018176,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,dimethyl fumarate,DB08908
,8200,DB00175,10016173,330,7801,193,5913,0.005214662,1.296003155,1.078222032,1.56112431,0.021157272,DB0017510016173_,3.85577158,0.259285032,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,8201,DB00476,10016173,697,16560,233,5944,0.382394174,1.073726765,0.921551071,1.254547814,0.552477923,DB0047610016173_,0.593341805,0.071135555,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,8202,DB00557,10016173,145,5842,60,3007,0.178962039,1.243835255,0.911418231,1.715525372,0.322612797,DB0055710016173_,1.131302446,0.218199554,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxyzine,DB00557
,8203,DB00678,10016173,522,15077,239,10485,7.94998118933715e-08,1.518864386,1.298086761,1.781248376,1.47003345453202e-06,DB0067810016173_,13.4302254,0.417962941,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,8204,DB00788,10016173,281,9075,111,4950,0.004407442,1.380805854,1.101343425,1.740941358,0.018473865,DB0078810016173_,3.991398244,0.322667281,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,8205,DB00829,10016173,289,7763,98,4356,1.18581074744798e-05,1.654678499,1.307320827,2.109057333,0.000126037,DB0082910016173_,8.978932304,0.50360673,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,8206,DB01050,10016173,438,17670,197,9174,0.098781244,1.154310279,0.971549937,1.375322708,0.208984261,DB0105010016173_,1.565496336,0.143503005,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,8207,DB05259,10016173,668,10602,165,2563,0.821586747,0.978708781,0.819482342,1.174122575,0.904955587,DB0525910016173_,0.099869412,-0.021521146,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,glatiramer,DB05259
,8208,DB08908,10016173,526,10147,154,3125,0.610265327,1.051879243,0.873237489,1.272938337,0.752419162,DB0890810016173_,0.284461714,0.050578319,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,dimethyl fumarate,DB08908
,8209,DB00175,10020772,117,8014,80,6026,0.562126723,1.099725394,0.818773129,1.483333027,0.714413544,DB0017510020772_,0.336293291,0.095060507,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,pravastatin,DB00175
,8210,DB00338,10020772,476,33198,258,22014,0.009816713,1.223394185,1.048120542,1.430538819,0.035049212,DB0033810020772_,3.351002158,0.201629115,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,omeprazole,DB00338
,8211,DB00476,10020772,233,17024,81,6096,0.846879336,1.030056068,0.795199168,1.345687901,0.923105324,DB0047610020772_,0.08001194,0.029613236,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,duloxetine,DB00476
,8212,DB00557,10020772,80,5907,40,3027,1,1.024883649,0.690850268,1.541884513,1,DB0055710020772_,0,0.024579093,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,hydroxyzine,DB00557
,8213,DB00678,10020772,326,15273,203,10521,0.28339471,1.106273974,0.923883625,1.327109466,0.447752229,DB0067810020772_,0.803515259,0.100997588,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,losartan,DB00678
,8214,DB00788,10020772,130,9226,46,5015,0.013527339,1.536140259,1.08755302,2.203650897,0.045286391,DB0078810020772_,3.094748701,0.429272945,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,naproxen,DB00788
,8215,DB00829,10020772,100,7952,37,4417,0.038716718,1.501191168,1.018039159,2.256651549,0.103075957,DB0082910020772_,2.272289116,0.406258905,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,diazepam,DB00829
,8216,DB00996,10020772,403,38550,204,22221,0.138233887,1.138732583,0.959024503,1.35537145,0.267285399,DB0099610020772_,1.31943828,0.129915875,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,gabapentin,DB00996
,8217,DB01050,10020772,222,17886,85,9286,0.018086965,1.355958881,1.050029283,1.764580892,0.05706931,DB0105010020772_,2.863488785,0.304508865,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ibuprofen,DB01050
,8218,DB05259,10020772,63,11207,9,2719,0.177700861,1.698240019,0.838735419,3.889534657,0.320926164,DB0525910020772_,1.1365442,0.529592432,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,glatiramer,DB05259
,8220,DB00338,10021015,170,33504,78,22194,0.007570422,1.443744313,1.097334627,1.913734845,0.02850022,DB0033810021015_,3.557843468,0.367239956,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,8223,DB00678,10021015,45,15554,24,10700,0.329339205,1.289848382,0.768786637,2.214866463,0.497998953,DB0067810021015_,0.697157304,0.254524678,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,8226,DB00996,10021015,124,38829,37,22388,0.000285676,1.932299052,1.328389524,2.871551817,0.001938808,DB0099610021015_,6.245681868,0.658710513,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,8227,DB01050,10021015,86,18022,38,9333,0.448511289,1.171991734,0.790565962,1.766687269,0.616215102,DB0105010021015_,0.484159185,0.158704639,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,ibuprofen,DB01050
,8231,DB00338,10036653,85,33589,50,22222,0.538674872,1.124721242,0.783618863,1.629173614,0.69458005,DB0033810036653_,0.364447861,0.11753522,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,8234,DB00678,10036653,34,15565,28,10696,0.518367865,0.83444678,0.490773816,1.429431804,0.677656446,DB0067810036653_,0.389114836,-0.180986312,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,losartan,DB00678
,8237,DB00996,10036653,56,38897,44,22381,0.145186163,0.732341948,0.48447586,1.113194644,0.277313037,DB0099610036653_,1.282608312,-0.311507733,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,8241,DB00175,10037660,134,7997,118,5988,0.22237535,0.850322993,0.657396139,1.101057866,0.376474048,DB0017510037660_,0.976906164,-0.16213901,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,8242,DB00476,10037660,266,16991,94,6083,0.951972774,1.013103565,0.79630026,1.298204715,0.990021368,DB0047610037660_,0.010028752,0.013018456,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,8243,DB00557,10037660,132,5855,67,3000,1,1.009469216,0.744147411,1.380264561,1,DB0055710037660_,0,0.009424664,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,8244,DB00678,10037660,241,15358,180,10544,0.39584297,0.919214866,0.753407509,1.123140938,0.56547459,DB0067810037660_,0.570089918,-0.084235379,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,8245,DB00788,10037660,170,9186,87,4974,0.692874319,1.058056939,0.810418657,1.389563832,0.814954759,DB0078810037660_,0.204622678,0.05643415,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,8246,DB00829,10037660,153,7899,86,4368,0.891768174,0.983786774,0.748480089,1.300062401,0.955008248,DB0082910037660_,0.046035302,-0.016346099,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,8247,DB05259,10037660,148,11122,52,2676,0.024185597,0.684817932,0.494601547,0.961122309,0.071654467,DB0525910037660_,2.635899785,-0.378602269,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,8248,DB08908,10037660,128,10545,35,3244,0.578233305,1.125050943,0.767077683,1.688996605,0.727026975,DB0890810037660_,0.318791698,0.117828318,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,8260,DB08908,10005169,50,10623,17,3262,0.667781178,0.90313948,0.511219829,1.672743337,0.798191412,DB0890810005169_,0.225406845,-0.101878274,NA,10005169,Blindness,10015919,Eye disorders,Eye,dimethyl fumarate,DB08908
,8262,DB08908,10013573,253,10420,55,3224,0.017330595,1.423204495,1.056451792,1.946876464,0.05524311,DB0890810013573_,2.896011643,0.352911016,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,8263,DB00190,10013395,27,3270,58,4616,0.076664636,0.657167569,0.399197192,1.057159775,0.172656187,DB0019010013395_,1.756453022,-0.419816242,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,8264,DB00264,10013395,53,29554,55,24837,0.288307248,0.809840297,0.544479527,1.203532704,0.453304061,DB0026410013395_,0.791192161,-0.210918215,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,8265,DB00316,10013395,126,65348,66,36887,0.652339863,1.07763164,0.793642635,1.474761937,0.786610866,DB0031610013395_,0.240021605,0.074765707,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,8266,DB00331,10013395,44,24902,47,20705,0.247167151,0.778396064,0.503841605,1.200553475,0.406328637,DB0033110013395_,0.900592997,-0.250519805,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,metformin,DB00331
,8268,DB00904,10013395,47,23022,22,14434,0.268365497,1.339416085,0.79093598,2.334983864,0.430843614,DB0090410013395_,0.842010098,0.292233761,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,8273,DB00190,10017577,148,3149,203,4471,0.781736869,1.035152326,0.82759874,1.292314545,0.881167872,DB0019010017577_,0.126507124,0.03454859,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,8274,DB00264,10017577,367,29240,255,24637,0.018868186,1.212647243,1.029799277,1.429705234,0.059028827,DB0026410017577_,2.829729368,0.192805774,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,8275,DB00316,10017577,867,64607,332,36621,6.17706088482799e-10,1.480232572,1.301930463,1.686021036,1.78128409608013e-08,DB0031610017577_,17.84334624,0.392199219,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,8276,DB00331,10017577,310,24636,189,20563,0.000685919,1.36902843,1.137688512,1.65085531,0.004024414,DB0033110017577_,5.515375932,0.314101313,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,8277,DB00654,10017577,31,3785,28,2570,0.288314145,0.751790936,0.435166113,1.304149901,0.453304061,DB0065410017577_,0.791192161,-0.285297004,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,8278,DB00904,10017577,243,22826,108,14348,0.002871762,1.41429532,1.121770007,1.792694434,0.013048274,DB0090410017577_,4.339099405,0.3466314,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,8279,DB00927,10017577,97,7400,51,4965,0.177096405,1.276088154,0.898219334,1.831694743,0.32016818,DB0092710017577_,1.138908859,0.243799269,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,8280,DB01592,10017577,117,6159,29,3038,0.000679246,1.989928101,1.31229377,3.107964941,0.003992391,DB0159210017577_,5.523365089,0.688098508,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,8281,DB06228,10017577,108,15804,53,16023,1.15119804936126e-05,2.06591615,1.472642086,2.929087419,0.000122731,DB0622810017577_,9.005518475,0.725573784,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,8282,DB09020,10017577,35,1919,19,1585,0.168110654,1.521311289,0.842922523,2.827077667,0.308283988,DB0902010017577_,1.176733883,0.419572653,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,bisacodyl,DB09020
,8283,DB00190,10019211,103,3194,60,4614,1.80996220014308e-08,2.479594506,1.780238835,3.479837127,3.82588310661526e-07,DB0019010019211_,14.77630633,0.908095041,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,8284,DB00264,10019211,1144,28463,487,24405,5.54817554081722e-40,2.014089993,1.807308918,2.247252501,2.17662379239374e-37,DB0026410019211_,84.41787348,0.700167477,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,8285,DB00654,10019211,123,3693,39,2559,1.0319303220209e-05,2.185145623,1.507108736,3.230420249,0.000111554,DB0065410019211_,9.101004234,0.781682473,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,latanoprost,DB00654
,8286,DB00904,10019211,1163,21906,334,14122,2.56877588839631e-42,2.244684219,1.982141997,2.547638669,1.08903668107253e-39,DB0090410019211_,89.7155251,0.808564852,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,8287,DB00927,10019211,403,7094,130,4886,9.43327994574132e-15,2.134992045,1.741606123,2.631220888,5.59084021135988e-13,DB0092710019211_,28.21247663,0.758462921,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,8288,DB01592,10019211,371,5905,66,3001,1.02383690824241e-17,2.856503903,2.184487886,3.784017592,8.52981081874857e-16,DB0159210019211_,34.6977943,1.049598465,female,10019211,Headache,10029205,Nervous system disorders,Nerv,iron,DB01592
,8289,DB06228,10019211,516,15396,237,15839,6.75688690249404e-26,2.239817368,1.913610939,2.627811083,1.10313523125501e-23,DB0622810019211_,52.8613008,0.80639433,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,8290,DB09020,10019211,50,1904,26,1578,0.061959987,1.593604929,0.968144867,2.680300243,0.147080129,DB0902010019211_,1.916777749,0.465998701,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,bisacodyl,DB09020
,8301,DB00203,10021789,180,13698,93,8845,0.091999199,1.249742065,0.966223557,1.625436809,0.198432605,DB0020310021789_,1.617305759,0.222937182,NA,10021789,Infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,8303,DB01164,10069568,52,6472,64,7872,1,0.988257277,0.670891079,1.449881385,1,DB0116410069568_,0,-0.011812214,NA,10069568,Ultrafiltration failure,10017947,Gastrointestinal disorders,Gastr,calcium chloride,DB01164
,8304,DB00682,10011781,108,19351,22,16342,5.37333024076901e-12,4.145521424,2.601869995,6.892446258,2.15795241220189e-10,DB0068210011781_,22.25669112,1.422028577,female,10011781,Cystitis,10021881,Infections and infestations,Infec,warfarin,DB00682
,8305,DB08932,10011781,100,19343,16,6581,0.003625658,2.12648072,1.246169217,3.866126643,0.015763859,DB0893210011781_,4.150035348,0.754468369,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,macitentan,DB08932
,8306,DB08932,10038435,287,19156,111,6486,0.245413072,0.875470075,0.699492595,1.101997438,0.404228763,DB0893210038435_,0.905774317,-0.132994308,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,macitentan,DB08932
,8307,DB00682,10061105,77,19382,32,16332,0.000680187,2.027520584,1.325619209,3.166864938,0.00399703,DB0068210061105_,5.522203752,0.706813659,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,8308,DB08932,10061105,211,19232,102,6495,0.003937287,0.698624162,0.548002785,0.895377281,0.016859426,DB0893210061105_,4.082845345,-0.358642362,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,8309,DB00073,10013968,332,7074,296,6111,0.712547417,0.968924454,0.822751731,1.141510891,0.829078987,DB0007310013968_,0.187439849,-0.031568633,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rituximab,DB00073
,8315,DB00181,10013082,46,9810,34,5837,0.354837268,0.805029166,0.504962196,1.29494427,0.524660382,DB0018110013082_,0.645004117,-0.216876771,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,8319,DB00181,10033371,671,9185,354,5517,0.056981498,1.138549989,0.99505821,1.304301606,0.137743935,DB0018110033371_,1.982358859,0.129755513,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,8320,DB00297,10033371,135,1537,100,779,0.00757997,0.68430413,0.516696647,0.90860565,0.028530038,DB0029710033371_,3.556797765,-0.379352826,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,bupivacaine,DB00297
,8321,DB00327,10033371,378,5760,238,4024,0.236984466,1.10958037,0.936112544,1.317119151,0.394324028,DB0032710033371_,0.930582301,0.103981898,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,8322,DB00575,10033371,242,5002,121,3708,0.000502944,1.48254251,1.181849059,1.867605605,0.003105613,DB0057510033371_,5.774544187,0.393758526,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,8323,DB00181,10033775,192,9664,66,5805,6.96549788242885e-05,1.747382222,1.311893789,2.35248414,0.000584573,DB0018110033775_,7.444629721,0.558118795,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,8325,DB00327,10033775,59,6079,23,4239,0.017659804,1.788674848,1.085988457,3.040212669,0.056047808,DB0032710033775_,2.881550244,0.581475037,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,8326,DB00575,10033775,51,5193,36,3793,0.913491091,1.034742191,0.660779551,1.635677169,0.961296669,DB0057510033775_,0.039472209,0.034152305,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,8327,DB00181,10047571,79,9777,22,5849,0.000910247,2.148131671,1.323559089,3.623917838,0.005100916,DB0018110047571_,5.278335191,0.764598474,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,baclofen,DB00181
,8333,DB00186,10015090,99,16802,57,9951,0.933832596,1.028646645,0.734470987,1.452518444,0.974425955,DB0018610015090_,0.025906746,0.028244001,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,8335,DB00787,10015090,73,16927,81,17167,0.628121473,0.91403164,0.656414165,1.270790852,0.767433143,DB0078710015090_,0.264703914,-0.089890091,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,8336,DB00820,10015090,184,11731,49,5767,7.78280760179919e-05,1.845963933,1.3381792,2.588427326,0.000643204,DB0082010015090_,7.3490483,0.613001598,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,8338,DB01069,10015090,46,6654,11,2384,0.290440828,1.498151767,0.762854534,3.212868241,0.455666537,DB0106910015090_,0.785994016,0.404232193,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,promethazine,DB01069
,8339,DB00186,10061024,61,16840,34,9974,0.832017371,1.062624073,0.686937247,1.668668514,0.912322753,DB0018610061024_,0.091761455,0.06074139,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,lorazepam,DB00186
,8340,DB00316,10061024,256,65218,201,36752,0.000516711,0.717751382,0.594072527,0.86810135,0.003171824,DB0031610061024_,5.753448506,-0.331632035,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,8342,DB00682,10061024,223,19236,165,16199,0.218961744,1.138122205,0.925384987,1.402068505,0.372289495,DB0068210061024_,0.988083516,0.129379716,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,warfarin,DB00682
,8343,DB00761,10061024,106,15201,92,8533,0.002853801,0.646749394,0.483886495,0.865846881,0.012984518,DB0076110061024_,4.343997568,-0.435796394,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,8344,DB00787,10061024,75,16925,144,17104,4.79486372764739e-06,0.526354328,0.392398393,0.701158207,5.70156041986934e-05,DB0078710061024_,9.77218557,-0.641780665,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,acyclovir,DB00787
,8345,DB00820,10061024,141,11774,73,5743,0.714238262,0.942134489,0.703936541,1.269936344,0.830568395,DB0082010061024_,0.185644999,-0.059607245,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,tadalafil,DB00820
,8347,DB01069,10061024,36,6664,18,2377,0.277087892,0.713413997,0.393773955,1.33721648,0.440608302,DB0106910061024_,0.819599002,-0.337693387,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,promethazine,DB01069
,8348,DB08895,10039073,932,27182,195,6451,0.123405721,1.134292736,0.968607238,1.333663688,0.246258684,DB0889510039073_,1.401372736,0.126009317,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,8349,DB08895,10043414,68,28046,13,6633,0.572116163,1.237090587,0.676835217,2.442799445,0.722151044,DB0889510043414_,0.32552096,0.212762322,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,8351,DB01285,10019211,73,1203,10,599,1.97584100727329e-05,3.632938515,1.849973539,7.950406832,0.000197697,DB0128510019211_,8.528775407,1.290041829,female,10019211,Headache,10029205,Nervous system disorders,Nerv,corticotropin,DB01285
,8353,DB01285,10042674,37,1239,16,593,0.881669631,1.106727153,0.595014077,2.149096262,0.950483399,DB0128510042674_,0.050784582,0.101407149,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,corticotropin,DB01285
,8355,DB00678,10037844,447,15152,298,10426,0.705298741,1.032142678,0.887474312,1.201741864,0.823415017,DB0067810037844_,0.194294932,0.031636912,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,8362,DB00678,10037884,79,15520,48,10676,0.527236289,1.132176458,0.780382775,1.657615658,0.684879755,DB0067810037884_,0.378511996,0.12414185,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,8364,DB00254,10050584,58,5877,21,3367,0.077968702,1.58225359,0.943934882,2.749848257,0.174946206,DB0025410050584_,1.743276747,0.458850154,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,doxycycline,DB00254
,8365,DB00678,10050584,132,15467,75,10649,0.201253832,1.211732914,0.90485606,1.632887263,0.350479145,DB0067810050584_,1.048454076,0.192051495,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,8367,DB00813,10038687,35,10537,27,10141,0.445742047,1.247563654,0.733111447,2.144719441,0.613581754,DB0081310038687_,0.488441765,0.221192572,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,8368,DB00412,10002383,46,1018,58,1328,0.919556704,1.034620371,0.680759136,1.564672697,0.964391651,DB0041210002383_,0.03625779,0.034034568,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,8372,DB01136,10002383,21,9863,41,11074,0.041249454,0.575100228,0.322609167,0.996771744,0.108207775,DB0113610002383_,2.223702054,-0.553210945,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,carvedilol,DB01136
,8373,DB00736,10007559,75,10516,55,5498,0.063502175,0.712926323,0.495974668,1.030443384,0.149787291,DB0073610007559_,1.898539055,-0.338377198,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,esomeprazole,DB00736
,8375,DB01098,10007559,83,8066,74,7135,1,0.992160823,0.715230134,1.378514878,1,DB0109810007559_,0,-0.007870065,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,rosuvastatin,DB01098
,8376,DB01136,10007559,260,9624,335,10780,0.09577137,0.869350271,0.734713483,1.027778146,0.204438255,DB0113610007559_,1.587489279,-0.140009162,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,carvedilol,DB01136
,8377,DB00736,10011078,30,10561,30,5523,0.013786578,0.522965866,0.30426791,0.898953694,0.045987336,DB0073610011078_,3.079389216,-0.648239083,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,esomeprazole,DB00736
,8379,DB01098,10011078,30,8119,49,7160,0.008937666,0.539954858,0.330543631,0.868817869,0.032531544,DB0109810011078_,3.425545073,-0.61626974,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,rosuvastatin,DB01098
,8380,DB01136,10011078,30,9854,85,11030,5.13489274368281e-06,0.395097457,0.251233949,0.606014949,6.06609688843608e-05,DB0113610011078_,9.710210083,-0.928622819,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,carvedilol,DB01136
,8381,DB00412,10022116,33,1031,45,1341,0.907761109,0.953841605,0.585091098,1.540709945,0.958771936,DB0041210022116_,0.042102046,-0.047257653,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,rosiglitazone,DB00412
,8386,DB00736,10028596,68,10523,64,5489,0.000869933,0.554217107,0.387478143,0.793622223,0.004912181,DB0073610028596_,5.316037308,-0.59019878,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,esomeprazole,DB00736
,8388,DB01098,10028596,83,8066,131,7078,3.1285345210177e-05,0.556007263,0.416336916,0.73898292,0.00029439,DB0109810028596_,8.130604065,-0.586973921,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,rosuvastatin,DB01098
,8395,DB00331,10002388,20,24926,40,20712,0.001061932,0.415475727,0.230036877,0.727951751,0.005788653,DB0033110002388_,5.151855726,-0.878331085,NA,10002388,Angina unstable,10007541,Cardiac disorders,Card,metformin,DB00331
,8397,DB00412,10002388,41,1023,81,1305,0.024740751,0.645817095,0.428365934,0.96095248,0.072929308,DB0041210002388_,2.61826469,-0.43723895,NA,10002388,Angina unstable,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,8403,DB00335,10011078,18,8448,41,5424,2.99830772327615e-06,0.281899385,0.152244523,0.502415124,3.78896723588046e-05,DB0033510011078_,10.18083198,-1.266205064,male,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,atenolol,DB00335
,8404,DB00451,10011078,54,47217,57,15362,1.38046930531253e-09,0.308232896,0.2083555,0.455535404,3.73117076505295e-08,DB0045110011078_,17.10395868,-1.176899625,male,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,8407,DB00177,10016807,36,4764,24,2826,0.688410866,0.889815071,0.515219054,1.562484194,0.812176199,DB0017710016807_,0.208037969,-0.116741623,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,valsartan,DB00177
,8408,DB00331,10016807,132,24814,97,20655,0.387152779,1.132721038,0.864356918,1.488812008,0.557267673,DB0033110016807_,0.584709593,0.124622737,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,8409,DB00335,10016807,71,8395,33,5432,0.130496103,1.392109666,0.907487255,2.17563045,0.256474508,DB0033510016807_,1.360726002,0.330820342,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,atenolol,DB00335
,8411,DB00451,10016807,400,46871,114,15305,0.217088518,1.145730716,0.927447208,1.424639213,0.370014051,DB0045110016807_,0.994214299,0.136042613,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,8412,DB00455,10016807,59,9342,25,5093,0.305421881,1.286613058,0.792266877,2.146745033,0.472208349,DB0045510016807_,0.750334974,0.25201323,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,loratadine,DB00455
,8413,DB01098,10016807,55,8094,42,7167,0.477429451,1.159533279,0.760892437,1.778435099,0.642759952,DB0109810016807_,0.441983949,0.148017579,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,rosuvastatin,DB01098
,8414,DB01592,10016807,95,6181,27,3040,0.011380985,1.730420627,1.1155627,2.767156234,0.039473405,DB0159210016807_,3.232128116,0.548364516,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,iron,DB01592
,8415,DB00177,10028596,48,4752,45,2805,0.030503373,0.629696618,0.409258591,0.970299075,0.085788697,DB0017710028596_,2.455868018,-0.462517134,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,valsartan,DB00177
,8416,DB00335,10028596,70,8396,62,5403,0.0732113,0.726588376,0.507865639,1.041601655,0.166871229,DB0033510028596_,1.790532849,-0.319395157,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,atenolol,DB00335
,8417,DB00451,10028596,221,47050,147,15272,7.66750684741721e-11,0.487979701,0.393993501,0.605872316,2.5511445251185e-09,DB0045110028596_,19.78672375,-0.717481471,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,8418,DB00455,10028596,36,9365,38,5080,0.004784084,0.513905034,0.316137548,0.834043155,0.019745918,DB0045510028596_,3.92480849,-0.665716789,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,loratadine,DB00455
,8419,DB00177,10030124,77,4723,41,2809,0.631688253,1.116971042,0.752680515,1.678862332,0.770519547,DB0017710030124_,0.260690255,0.110620595,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,8420,DB00331,10030124,229,24717,192,20560,0.960794209,0.99211349,0.814650564,1.209324123,0.998338733,DB0033110030124_,0.001662648,-0.007917773,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,8421,DB00335,10030124,122,8344,63,5402,0.150591791,1.253683141,0.915708423,1.730920615,0.284757154,DB0033510030124_,1.256118555,0.226085731,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,8423,DB00451,10030124,616,46655,180,15239,0.199243534,1.11780295,0.944265371,1.328550194,0.348131504,DB0045110030124_,1.055174985,0.111365107,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,8424,DB00455,10030124,111,9290,50,5068,0.281518684,1.211032248,0.858212056,1.729870101,0.445470989,DB0045510030124_,0.808623154,0.191473093,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,8425,DB01098,10030124,101,8048,57,7152,0.006328653,1.574606474,1.125115241,2.222204894,0.024713807,DB0109810030124_,3.700393217,0.454005383,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,8426,DB01592,10030124,103,6173,38,3029,0.148315446,1.330009061,0.906047254,1.988834688,0.281671377,DB0159210030124_,1.267014217,0.285185755,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,8427,DB08932,10005191,44,19399,13,6584,0.761305672,1.148726576,0.607226577,2.326205991,0.867650712,DB0893210005191_,0.141966051,0.138654004,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,macitentan,DB08932
,8428,DB00005,10066044,76,128006,21,42398,0.556820316,1.198691072,0.731307153,2.047038756,0.710100421,DB0000510066044_,0.342348881,0.181230188,NA,10066044,Injection site papule,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,8429,DB00682,10003445,114,19345,71,16293,0.045998205,1.352304511,0.996037991,1.846667892,0.117487397,DB0068210003445_,2.141424207,0.301810182,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,8430,DB00820,10003445,132,11783,48,5768,0.079604477,1.346184954,0.959022753,1.917395764,0.177755715,DB0082010003445_,1.727345061,0.297274632,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,8433,DB00682,10028813,1564,17895,558,15806,9.49294133225318e-80,2.475439503,2.240639775,2.738255331,1.27959980983731e-76,DB0068210028813_,174.7499197,0.906417957,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,8434,DB00820,10056520,107,11808,17,5799,1.75232610464839e-06,3.090933513,1.840703874,5.507752714,2.35660740141637e-05,DB0082010056520_,10.65570242,1.128473153,female,10056520,Catheter site infection,10021881,Infections and infestations,Infec,tadalafil,DB00820
,8435,DB01240,10056520,230,5521,52,1524,0.209733028,1.220896501,0.894854993,1.692274779,0.360870137,DB0124010056520_,1.019237117,0.199585426,NA,10056520,Catheter site infection,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,8436,DB00682,10069868,86,19373,31,16333,2.37978057641831e-05,2.338751431,1.534003595,3.651752849,0.000231547,DB0068210069868_,8.370725916,0.849617211,NA,10069868,Device issue,10077536,Product issues,Prod,warfarin,DB00682
,8437,DB00820,10069868,78,11837,21,5795,0.013335218,1.818335409,1.110064765,3.104071847,0.044777237,DB0082010069868_,3.106055369,0.597921472,NA,10069868,Device issue,10077536,Product issues,Prod,tadalafil,DB00820
,8438,DB01240,10069868,105,5646,29,1547,1,0.992067317,0.649442033,1.558914111,1,DB0124010069868_,0,-0.007964315,NA,10069868,Device issue,10077536,Product issues,Prod,epoprostenol,DB01240
,8440,DB00222,10007559,47,3159,82,3046,0.001286364,0.552722902,0.376322269,0.803659707,0.006769187,DB0022210007559_,4.99537425,-0.592898485,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,glimepiride,DB00222
,8441,DB00222,10011078,25,3181,61,3067,5.0372244301779e-05,0.395196138,0.237043263,0.640947774,0.000444755,DB0022210011078_,7.717987891,-0.928373086,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,glimepiride,DB00222
,8442,DB00222,10028596,48,3158,82,3046,0.001829878,0.564659949,0.385561198,0.819097913,0.009046144,DB0022210028596_,4.705416678,-0.571531589,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,glimepiride,DB00222
,8445,DB08910,10020937,139,16605,112,17376,0.042501824,1.298682181,1.004297617,1.682472141,0.11070311,DB0891010020937_,2.200903347,0.261350043,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,8447,DB08932,10003239,667,18776,180,6417,0.005545121,1.266407722,1.069835194,1.505192188,0.022225299,DB0893210003239_,3.806524042,0.236184327,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,8448,DB08932,10019211,2817,16626,671,5926,9.28587555892396e-20,1.496345624,1.367875052,1.638560329,9.40575102375015e-18,DB0893210019211_,39.20521036,0.403025885,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,8449,DB08932,10047340,83,19360,19,6578,0.137730014,1.484210539,0.892649711,2.590446508,0.266526791,DB0893210047340_,1.322280511,0.394883007,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,macitentan,DB08932
,8451,DB00316,10020646,110,65364,140,36813,1.46645309401806e-10,0.442512475,0.341409394,0.572354766,4.65247067909049e-09,DB0031610020646_,19.18586743,-0.815286623,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,8453,DB00722,10020646,142,25261,350,25682,1.68023018729029e-20,0.412457594,0.336694072,0.503104488,1.82499382119526e-18,DB0072210020646_,40.84495507,-0.885621881,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,8455,DB00758,10020646,30,8270,38,10036,0.903274204,0.958054986,0.572678797,1.589502906,0.957348417,DB0075810020646_,0.043587882,-0.042850106,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,clopidogrel,DB00758
,8456,DB01115,10020646,20,3580,37,2231,9.03307068383949e-05,0.336920336,0.184781001,0.597458793,0.000732031,DB0111510020646_,7.219687661,-1.087908768,male,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,nifedipine,DB01115
,8458,DB00193,10021036,63,19257,31,8671,0.73773575,0.915086736,0.585816667,1.456794223,0.848898314,DB0019310021036_,0.163815871,-0.088736425,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,tramadol,DB00193
,8466,DB01076,10013950,155,25592,159,25424,0.777544971,0.968436598,0.770614935,1.216802401,0.878740499,DB0107610013950_,0.129265648,-0.032072262,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,8467,DB01098,10013950,45,8104,38,7171,0.912292663,1.047882852,0.664403946,1.660579809,0.960594091,DB0109810013950_,0.040203341,0.046771798,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,8468,DB00203,10007515,129,13749,98,8840,0.219220932,0.846351123,0.644869838,1.113659881,0.372549441,DB0020310007515_,0.987385523,-0.166820967,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,sildenafil,DB00203
,8471,DB00203,10028596,104,13774,81,8857,0.199378764,0.825623614,0.610745719,1.119359886,0.348309904,DB0020310028596_,1.054662668,-0.191616282,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,sildenafil,DB00203
,8472,DB00374,10028596,81,17635,33,5691,0.274260059,0.792116058,0.521769068,1.22754772,0.437408268,DB0037410028596_,0.826888269,-0.23304736,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,treprostinil,DB00374
,8473,DB08877,10011906,210,3079,374,2855,1.67122861663055e-13,0.52070507,0.434226531,0.623095019,8.31974321744963e-12,DB0887710011906_,25.51238972,-0.652571482,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,8474,DB00669,10069327,210,6167,46,1051,0.149716996,0.778047965,0.559033649,1.102649547,0.283585158,DB0066910069327_,1.260242821,-0.250967106,NA,10069327,Product quality issue,10077536,Product issues,Prod,sumatriptan,DB00669
,8476,DB00530,10012735,358,1450,148,1120,1.43262893972944e-09,1.868032767,1.51336381,2.314050069,3.84644041683231e-08,DB0053010012735_,17.07353259,0.624885881,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,erlotinib,DB00530
,8477,DB00530,10028813,181,1627,90,1178,0.005388165,1.455933762,1.111457277,1.917752576,0.021710417,DB0053010028813_,3.829963069,0.375647456,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,erlotinib,DB00530
,8478,DB00530,10047700,96,1712,62,1206,0.619655291,1.090737329,0.777294085,1.539792356,0.760331312,DB0053010047700_,0.274001004,0.086853917,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,erlotinib,DB00530
,8481,DB00530,10037844,363,1445,263,1005,0.682255803,0.959936622,0.800534035,1.152060437,0.807833406,DB0053010037844_,0.213399422,-0.040888016,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,erlotinib,DB00530
,8484,DB00005,10052252,36,128046,15,42404,0.422959059,0.794787066,0.42436817,1.562675538,0.591874723,DB0000510052252_,0.524460282,-0.229681042,NA,10052252,Upper respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,8486,DB00169,10019465,70,38621,25,18150,0.271216679,1.315911106,0.822535457,2.169561324,0.434027292,DB0016910019465_,0.834647863,0.274529282,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,8490,DB01202,10019465,28,6686,33,5685,0.246289675,0.721478037,0.419451404,1.232912705,0.405284923,DB0120210019465_,0.903164946,-0.326453342,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,8497,DB06290,10016256,33,329,34,639,0.016454632,1.883958578,1.108898448,3.197498285,0.052974464,DB0629010016256_,2.937945294,0.63337519,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,simeprevir,DB06290
,8498,DB08934,10016256,1008,3481,1369,4835,0.637499025,1.022709575,0.931469613,1.122683688,0.774784967,DB0893410016256_,0.25516975,0.022455551,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,8499,DB00005,10009944,46,128036,23,42396,0.124235656,0.662253305,0.393196238,1.144839745,0.247407699,DB0000510009944_,1.396717701,-0.41210716,NA,10009944,Colon cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,etanercept,DB00005
,8517,DB00588,10002034,233,16291,145,8323,0.070633377,0.820977263,0.66319287,1.018970618,0.162410734,DB0058810002034_,1.817626756,-0.197259864,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,fluticasone propionate,DB00588
,8518,DB00695,10002034,833,27216,547,19981,0.046549709,1.118058174,1.000902637,1.249570766,0.118592404,DB0069510002034_,2.132062841,0.111593408,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,furosemide,DB00695
,8519,DB00973,10002034,58,3793,27,2994,0.027322007,1.69551059,1.053650314,2.792111507,0.078703159,DB0097310002034_,2.542071981,0.527983929,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ezetimibe,DB00973
,8521,DB00335,10017955,61,8405,55,5410,0.085186872,0.713916777,0.486864019,1.048995448,0.18707803,DB0033510017955_,1.676229477,-0.336988882,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,8522,DB00695,10017955,425,27624,410,20118,6.3794261433839e-05,0.754937235,0.65674924,0.867836208,0.000542489,DB0069510017955_,7.519343547,-0.281120666,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,8523,DB00973,10017955,48,3803,41,2980,0.747336219,0.917387975,0.590274428,1.431610912,0.85627185,DB0097310017955_,0.155167372,-0.086224804,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ezetimibe,DB00973
,8524,DB01050,10017955,142,17966,146,9225,6.5162691184098e-09,0.499401614,0.39305408,0.63447931,1.52452277505475e-07,DB0105010017955_,15.69641422,-0.69434467,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,8528,DB00695,10027141,63,27986,51,20477,0.635330035,0.903851867,0.614612198,1.334819436,0.773400485,DB0069510027141_,0.256958273,-0.101089796,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,8530,DB01050,10027141,14,18094,52,9319,1.23190081025442e-13,0.138673205,0.070922704,0.254100013,6.20316337117577e-12,DB0105010027141_,25.80596173,-1.975635154,male,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,8531,DB06228,10027141,60,15852,106,15970,0.000440851,0.570264496,0.408033762,0.790640696,0.002780841,DB0622810027141_,5.885001758,-0.561654998,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,8533,DB00331,10008190,228,24718,255,20497,0.001097851,0.741443211,0.616788106,0.890851593,0.005944994,DB0033110008190_,5.125205682,-0.299156707,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,metformin,DB00331
,8534,DB00706,10008190,10,1065,169,15756,0.876747886,0.87540857,0.411040002,1.656600246,0.947373433,DB0070610008190_,0.054061931,-0.133064564,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,8537,DB01306,10008190,43,4165,46,3820,0.522419638,0.857369175,0.550964262,1.331844713,0.680971991,DB0130610008190_,0.384234104,-0.153886677,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,insulin aspart,DB01306
,8538,DB00264,10022116,59,29548,43,24849,0.488103849,1.153885591,0.765528131,1.75191096,0.651701995,DB0026410022116_,0.428167884,0.143135022,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,8539,DB00331,10022116,77,24869,40,20712,0.015476269,1.603204802,1.079972516,2.412564158,0.050508286,DB0033110022116_,2.985617884,0.472004627,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,8540,DB00381,10022116,48,29312,29,22858,0.302121721,1.2907245,0.797272431,2.123436174,0.468445118,DB0038110022116_,0.758336329,0.255203689,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,8541,DB00451,10022116,127,47144,25,15394,0.018277056,1.658709459,1.073489747,2.660320481,0.057537867,DB0045110022116_,2.855311987,0.506039866,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,8543,DB01076,10022116,37,25710,45,25538,0.378291679,0.816726211,0.513823891,1.290966,0.548313809,DB0107610022116_,0.600907511,-0.202451355,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,8544,DB01104,10022116,80,15383,17,7269,0.002071451,2.223625873,1.304640651,4.00735238,0.010012521,DB0110410022116_,4.603918885,0.79913914,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,8548,DB00264,10033371,986,28621,502,24390,2.97301398877243e-21,1.673765982,1.499604938,1.870035708,3.5520760315856e-19,DB0026410033371_,42.48158454,0.515076166,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,8549,DB00331,10033371,933,24013,441,20311,2.34290561407708e-24,1.789456556,1.593586972,2.011689067,3.45004336504292e-22,DB0033110033371_,49.41848525,0.581911974,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,8550,DB00381,10033371,1038,28322,442,22445,6.75666371764378e-29,1.861062798,1.6610536,2.087875618,1.39293259465307e-26,DB0038110033371_,59.53580111,0.621147722,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,8551,DB00451,10033371,1932,45339,368,15051,2.38391549331118e-24,1.742875829,1.55574498,1.95666758,3.5006267453455e-22,DB0045110033371_,49.40393002,0.555536524,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,8552,DB00706,10033371,35,1040,358,15567,0.045243377,1.463326748,0.997553508,2.087357128,0.116049979,DB0070610033371_,2.153734329,0.380712438,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,8553,DB01076,10033371,865,24882,516,25067,4.04893901155906e-21,1.688791521,1.510369751,1.889774955,4.75117687137633e-19,DB0107610033371_,42.19072442,0.524013197,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,8554,DB01104,10033371,525,14938,138,7148,8.33498660510274e-11,1.820379678,1.503049764,2.216808375,2.74199152584638e-09,DB0110410033371_,19.71458135,0.599045094,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,8556,DB01276,10033371,36,1981,21,1490,0.418703754,1.289300195,0.729190307,2.33482282,0.587719116,DB0127610033371_,0.531506139,0.254099586,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,8557,DB01306,10033371,134,4074,73,3793,0.000234178,1.70888792,1.270851334,2.313084073,0.001642743,DB0130610033371_,6.411387769,0.53584282,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,8565,DB00213,10006093,48,18847,57,13364,0.009634249,0.597142895,0.397842627,0.892983883,0.03455263,DB0021310006093_,3.365271621,-0.51559884,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,8566,DB00331,10006093,72,24874,101,20651,0.000720833,0.591857889,0.431014241,0.809236327,0.00419555,DB0033110006093_,5.473730878,-0.524488726,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,metformin,DB00331
,8567,DB00381,10006093,191,29169,175,22712,0.125362267,0.849829432,0.688068572,1.05013199,0.249160468,DB0038110006093_,1.389658141,-0.162719618,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,amlodipine,DB00381
,8569,DB00722,10006093,78,25325,165,25867,5.11934740714871e-08,0.482853422,0.363793046,0.636223165,9.87973910403112e-07,DB0072210006093_,13.82760955,-0.728042146,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,lisinopril,DB00722
,8571,DB01104,10006093,44,15419,25,7261,0.441224415,0.828829365,0.495781481,1.41426279,0.609404853,DB0110410006093_,0.495272449,-0.187740977,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,sertraline,DB01104
,8573,DB00381,10007625,46,29314,58,22829,0.017190359,0.617664934,0.409955809,0.92583409,0.054865955,DB0038110007625_,2.902862247,-0.481809147,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,amlodipine,DB00381
,8574,DB00722,10007625,17,25386,33,25999,0.033402607,0.527600145,0.275551265,0.975079258,0.092148145,DB0072210007625_,2.384357727,-0.639416583,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,lisinopril,DB00722
,8577,DB00213,10008479,364,18531,207,13214,0.010110425,1.253901109,1.052742741,1.496712721,0.03588583,DB0021310008479_,3.327412776,0.226259579,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,8578,DB00331,10008479,317,24629,256,20496,0.735688853,1.0304885,0.870308582,1.221055633,0.847284823,DB0033110008479_,0.165718369,0.030032962,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,8579,DB00412,10008479,43,1021,46,1340,0.383740427,1.22673496,0.7836085,1.917236119,0.553743022,DB0041210008479_,0.59105456,0.204356136,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,rosiglitazone,DB00412
,8580,DB00722,10008479,366,25037,338,25694,0.171852819,1.111252468,0.954875002,1.293538188,0.313255989,DB0072210008479_,1.160734567,0.105487728,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,8581,DB01067,10008479,62,4299,59,4764,0.411159308,1.16449103,0.800006854,1.696617685,0.580508268,DB0106710008479_,0.543851235,0.152284108,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,8582,DB01104,10008479,199,15264,83,7203,0.368975229,1.131397895,0.870082881,1.482259449,0.538596873,DB0110410008479_,0.618787905,0.123453944,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,8583,DB00213,10011078,40,18855,43,13378,0.058774522,0.660041279,0.417938773,1.040226371,0.141201748,DB0021310011078_,1.957565578,-0.415452902,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,8584,DB00381,10011078,49,29311,85,22802,6.76886189647866e-06,0.44845907,0.308758715,0.645094321,7.71941216433422e-05,DB0038110011078_,9.469187248,-0.801937862,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,amlodipine,DB00381
,8585,DB00722,10011078,51,25352,122,25910,1.54658137407264e-07,0.427211205,0.301738916,0.597340446,2.69932877938243e-06,DB0072210011078_,12.82250742,-0.850476764,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,lisinopril,DB00722
,8586,DB01067,10011078,23,4338,39,4784,0.125114698,0.650408631,0.370209707,1.11850256,0.248793398,DB0106710011078_,1.391132453,-0.43015445,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,glipizide,DB01067
,8588,DB00213,10021015,110,18785,68,13353,0.4016775,1.149839121,0.841488181,1.580955627,0.571407416,DB0021310021015_,0.55965281,0.139622038,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,8589,DB00331,10021015,102,24844,45,20707,0.000328828,1.889173247,1.317208364,2.747485547,0.002175498,DB0033110021015_,6.130497809,0.636139298,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,8590,DB00381,10021015,127,29233,83,22804,0.236094786,1.19360776,0.89755568,1.594541621,0.393354131,DB0038110021015_,0.933044976,0.176980452,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,8592,DB00722,10021015,97,25306,51,25981,9.62463490834949e-05,1.952655277,1.376617763,2.79873719,0.000771056,DB0072210021015_,7.167749337,0.669190127,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,8594,DB01104,10021015,77,15386,13,7273,0.000166404,2.799749816,1.543152737,5.497565992,0.001233831,DB0110410021015_,6.697631589,1.029530062,female,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,sertraline,DB01104
,8595,DB00331,10021097,347,24599,497,20255,2.86056139593877e-15,0.574909514,0.499139427,0.661588972,1.81398929534983e-13,DB0033110021097_,29.33807776,-0.553542618,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,metformin,DB00331
,8597,DB01067,10021097,52,4309,81,4742,0.054375941,0.706514148,0.487591045,1.01588893,0.133197111,DB0106710021097_,2.01592521,-0.347412052,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,glipizide,DB01067
,8598,DB01104,10021097,183,15280,97,7189,0.366920693,0.887625157,0.689046197,1.14932288,0.536556062,DB0110410021097_,0.622584226,-0.119205746,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sertraline,DB01104
,8599,DB00213,10028596,124,18771,144,13277,6.29418632866893e-05,0.609100771,0.47465366,0.78067014,0.000536542,DB0021310028596_,7.530365944,-0.495771556,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,8600,DB00381,10028596,201,29159,225,22662,0.000188839,0.694301285,0.570667154,0.844224026,0.001373063,DB0038110028596_,6.590711359,-0.364849284,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,amlodipine,DB00381
,8601,DB00722,10028596,218,25185,323,25709,2.17897172354681e-05,0.688973142,0.577002309,0.821429627,0.000214873,DB0072210028596_,8.445465609,-0.37255299,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,lisinopril,DB00722
,8602,DB01067,10028596,34,4327,82,4741,7.36482164537158e-05,0.454362141,0.294597276,0.687075925,0.000612997,DB0106710028596_,7.397151113,-0.788860732,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,glipizide,DB01067
,8603,DB01104,10028596,74,15389,58,7228,0.004788061,0.599261177,0.418727465,0.86126427,0.019757402,DB0110410028596_,3.924227088,-0.512057754,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,sertraline,DB01104
,8604,DB00213,10038435,329,18566,274,13147,0.05001582,0.850271475,0.72097183,1.003394066,0.125026652,DB0021310038435_,2.079228346,-0.162199598,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,8605,DB00381,10038435,296,29064,334,22553,3.22178519105766e-06,0.687706844,0.585482142,0.807410574,4.03260113080717e-05,DB0038110038435_,10.11851386,-0.374392631,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,8606,DB00722,10038435,245,25158,295,25737,0.062826623,0.84962579,0.713609183,1.010836332,0.148680812,DB0072210038435_,1.905953469,-0.162959274,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,8607,DB01067,10038435,47,4314,62,4761,0.385912403,0.836629123,0.558848975,1.245259686,0.556050682,DB0106710038435_,0.586895834,-0.17837441,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,glipizide,DB01067
,8608,DB01104,10038435,84,15379,77,7209,2.88220764610499e-05,0.511367688,0.370366547,0.706953364,0.000274026,DB0110410038435_,8.202287804,-0.670666401,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,sertraline,DB01104
,8609,DB00005,10025082,213,127869,79,42340,0.379266734,0.892754177,0.686374894,1.171241253,0.5492879,DB0000510025082_,0.599132566,-0.113444014,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,8610,DB00005,10061024,205,127877,121,42298,9.34514250048946e-07,0.560405482,0.445323033,0.707696867,1.35076750412629e-05,DB0000510061024_,11.21225251,-0.579094683,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,etanercept,DB00005
,8612,DB00005,10002034,304,127778,74,42345,0.017075369,1.361385579,1.05251812,1.7803426,0.054578473,DB0000510002034_,2.908115742,0.308502989,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,etanercept,DB00005
,8613,DB00065,10002034,62,9402,47,4910,0.067842992,0.688891381,0.463195939,1.030598831,0.157447736,DB0006510002034_,1.848661712,-0.372671668,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,infliximab,DB00065
,8614,DB00207,10002034,142,8938,56,5399,0.00764356,1.531655503,1.114445132,2.130144267,0.028724137,DB0020710002034_,3.550017489,0.426349178,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,azithromycin,DB00207
,8615,DB00065,10003239,320,9144,146,4811,0.165292924,1.153188862,0.942139837,1.416804677,0.30452965,DB0006510003239_,1.188986825,0.142531028,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,infliximab,DB00065
,8616,DB00207,10003239,137,8943,46,5409,0.000391556,1.801274147,1.27874564,2.57806964,0.002518857,DB0020710003239_,5.983949898,0.588494274,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,azithromycin,DB00207
,8617,DB00065,10003988,126,9338,69,4888,0.761855745,0.955880248,0.705627523,1.304071379,0.868007987,DB0006510003988_,0.141554363,-0.045122637,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,infliximab,DB00065
,8618,DB00207,10003988,122,8958,62,5393,0.319207407,1.18467049,0.863905887,1.638472625,0.487344506,DB0020710003988_,0.718784002,0.169464669,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,azithromycin,DB00207
,8619,DB00065,10013700,511,8953,111,4846,1.40856299399732e-20,2.491658134,2.019035895,3.097227681,1.56550013941731e-18,DB0006510013700_,40.99832632,0.912948406,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,infliximab,DB00065
,8620,DB00207,10013700,1561,7519,330,5125,1.36074820720949e-91,3.223772481,2.84545076,3.660736014,2.30756558880655e-88,DB0020710013700_,201.7912951,1.170552252,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,azithromycin,DB00207
,8621,DB00065,10017577,48,9416,21,4936,0.527694132,1.198164003,0.702847692,2.109378134,0.685234831,DB0006510017577_,0.377993681,0.180790388,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,8622,DB00207,10017577,51,9029,20,5435,0.110955064,1.534927482,0.898019185,2.72118975,0.227527996,DB0020710017577_,1.480481991,0.428483137,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,8627,DB00207,10028391,34,9046,19,5436,0.887373824,1.075349264,0.595530529,1.997712247,0.953324525,DB0020710028391_,0.047799903,0.072645506,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,azithromycin,DB00207
,8628,DB00065,10033425,146,9318,38,4919,5.98613800703644e-05,2.028170187,1.408283795,2.984832074,0.00051479,DB0006510033425_,7.571751037,0.707134001,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,infliximab,DB00065
,8629,DB00207,10033425,105,8975,34,5421,0.001437738,1.865253087,1.254133715,2.837381918,0.007426008,DB0020710033425_,4.902766877,0.623396747,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,azithromycin,DB00207
,8632,DB00065,10046735,222,9242,102,4855,0.287075945,1.143319454,0.897898428,1.463852508,0.451890889,DB0006510046735_,0.794314523,0.133935833,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,infliximab,DB00065
,8633,DB00207,10046735,129,8951,49,5406,0.005034742,1.589955183,1.13382884,2.260875485,0.020578165,DB0020710046735_,3.883524694,0.463705829,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,azithromycin,DB00207
,8634,DB00005,10047461,358,127724,93,42326,0.038081907,1.275647611,1.012526854,1.620770919,0.101763433,DB0000510047461_,2.285104443,0.24345398,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,8636,DB00207,10047461,42,9038,24,5431,0.899124809,1.051588495,0.621490708,1.817577602,0.956490275,DB0020710047461_,0.044484657,0.050301873,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,azithromycin,DB00207
,8637,DB00065,10052904,76,9388,31,4926,0.261831525,1.286406485,0.835519594,2.024436212,0.423509532,DB0006510052904_,0.859179258,0.251852661,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,infliximab,DB00065
,8639,DB00571,10006093,84,5039,68,2541,0.005374978,0.622940665,0.445389832,0.873965121,0.021670571,DB0057110006093_,3.831800099,-0.473304006,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,propranolol,DB00571
,8641,DB00188,10012735,630,7256,455,8373,1.21745530459323e-13,1.597699817,1.408102173,1.813918152,6.15400243869866e-12,DB0018810012735_,25.81391844,0.46856498,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,8642,DB00295,10012735,435,14228,287,9315,0.938420952,0.992306842,0.850889883,1.158578846,0.978144719,DB0029510012735_,0.022097646,-0.007722903,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,8643,DB00398,10012735,120,607,243,1295,0.66802489,1.053527164,0.821973174,1.345415211,0.798342817,DB0039810012735_,0.225217179,0.052143739,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sorafenib,DB00398
,8644,DB00904,10012735,1779,21290,858,13598,3.94318909913479e-11,1.32429455,1.216517382,1.442435598,1.37371405527844e-09,DB0090410012735_,20.40574778,0.280879902,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,8652,DB00973,10067482,47,3804,31,2990,0.492255981,1.19166916,0.739341865,1.94550193,0.655169804,DB0097310067482_,0.422860834,0.17535498,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,8653,DB01261,10067482,105,3676,81,3222,0.41318544,1.136177385,0.838742453,1.543776126,0.582615788,DB0126110067482_,0.540227335,0.127669457,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,8654,DB08816,10008479,52,1099,73,1829,0.396431482,1.185409854,0.807605148,1.729708797,0.566027084,DB0881610008479_,0.56911335,0.170088583,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ticagrelor,DB08816
,8656,DB00559,10028810,241,9418,61,3245,0.032506957,1.361208974,1.020820785,1.83899986,0.090212254,DB0055910028810_,2.405590012,0.308373257,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,bosentan,DB00559
,8657,DB01164,10037087,43,6481,39,7897,0.183864002,1.343419408,0.849396685,2.130742047,0.328777529,DB0116410037087_,1.112373959,0.295218161,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,calcium chloride,DB01164
,8659,DB00169,10064658,61,38630,28,18147,1,1.023432516,0.643990708,1.663718994,1,DB0016910064658_,0,0.023162189,NA,10064658,Osteonecrosis of jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,8660,DB00399,10064658,156,6836,116,4882,0.756027055,0.960401395,0.748222417,1.23570052,0.863200536,DB0039910064658_,0.147108244,-0.040403962,NA,10064658,Osteonecrosis of jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,8661,DB01373,10064658,70,22650,19,7362,0.53895684,1.197479351,0.712393121,2.107604008,0.694827012,DB0137310064658_,0.364092368,0.180218807,NA,10064658,Osteonecrosis of jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,8665,DB00363,10029366,67,4561,107,6781,0.697078988,0.930941354,0.673884141,1.278315646,0.817741334,DB0036310029366_,0.20120921,-0.071558996,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,clozapine,DB00363
,8666,DB00363,10047942,52,4576,63,6825,0.293206304,1.231027672,0.834279315,1.809747734,0.458815583,DB0036310047942_,0.77910693,0.207849326,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,clozapine,DB00363
,8667,DB00904,10013709,630,22439,306,14150,0.000206204,1.298278028,1.128850357,1.495627496,0.001477866,DB0090410013709_,6.517156034,0.261038793,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,8668,DB00433,10028813,871,6785,447,5573,4.32871120667814e-15,1.60041833,1.418372576,1.807655833,2.68349467140413e-13,DB0043310028813_,28.94648628,0.470265052,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,8669,DB00433,10047700,530,7126,264,5756,2.05993592495518e-10,1.621551465,1.390463407,1.89452465,6.40016735076206e-09,DB0043310047700_,18.8669417,0.483383385,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,8670,DB00904,10047700,1510,21559,698,13758,3.58859190681757e-12,1.380525055,1.257992251,1.516074235,1.47208965232659e-10,DB0090410047700_,22.63916801,0.322463901,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,8672,DB00904,10049414,32,23037,25,14431,0.416256866,0.801840992,0.460196981,1.411927186,0.585533357,DB0090410049414_,0.535232126,-0.220844955,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,8673,DB00333,10013700,127,2944,31,3121,5.88857640587401e-16,4.341694306,2.902223869,6.677724035,4.04128540021928e-14,DB0033310013700_,30.83962849,1.468264665,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,methadone,DB00333
,8674,DB06703,10028813,121,654,95,316,0.001993354,0.615660089,0.451098919,0.841713908,0.009695653,DB0670310028813_,4.636077608,-0.485060271,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,gadobutrol,DB06703
,8675,DB00005,10013990,115,127967,46,42373,0.274663115,0.827789862,0.583149983,1.192309955,0.437920838,DB0000510013990_,0.82571712,-0.188995947,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,etanercept,DB00005
,8676,DB00005,10029148,259,127823,126,42293,0.000595426,0.680126907,0.547454337,0.848579003,0.003574051,DB0000510029148_,5.634055605,-0.385475871,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,etanercept,DB00005
,8677,DB00005,10052428,213,127869,62,42357,0.402430135,1.138012004,0.85375956,1.535888644,0.572256544,DB0000510052428_,0.558167885,0.129282884,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,8685,DB01164,10021097,299,6225,320,7616,0.10743566,1.143152192,0.969600009,1.347486072,0.222322966,DB0116410021097_,1.503624153,0.133789527,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,calcium chloride,DB01164
,8690,DB00658,10054112,38,1265,33,1363,0.400675479,1.240620706,0.752461562,2.054989244,0.570533057,DB0065810054112_,0.561184167,0.215611823,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,sevelamer,DB00658
,8691,DB00404,10013709,961,18931,345,9517,8.35251528484613e-08,1.400316218,1.233797242,1.592225296,1.53636014179273e-06,DB0040410013709_,13.38609448,0.336698081,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,8692,DB00404,10039203,69,19823,36,9826,0.83560161,0.950068609,0.625621407,1.464910029,0.914871949,DB0040410039203_,0.08897117,-0.051221077,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,8698,DB00153,10007559,70,7353,31,3408,0.914533043,1.046572777,0.675049161,1.656518972,0.961770867,DB0015310007559_,0.038979041,0.045520804,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,ergocalciferol,DB00153
,8699,DB00186,10007559,84,16817,63,9945,0.1708133,0.78850812,0.561418772,1.112230667,0.311934385,DB0018610007559_,1.164962416,-0.237612574,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,lorazepam,DB00186
,8700,DB00370,10007559,38,4503,25,3638,0.44806129,1.227985685,0.720693893,2.126705068,0.615829019,DB0037010007559_,0.484785921,0.205375173,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,mirtazapine,DB00370
,8701,DB00421,10007559,225,8678,174,5078,0.007282876,0.756702657,0.616101959,0.930528013,0.027619061,DB0042110007559_,3.589249125,-0.278784894,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,spironolactone,DB00421
,8702,DB00451,10007559,383,46888,192,15227,2.16432401805053e-06,0.647819059,0.542757519,0.775254482,2.84091170109654e-05,DB0045110007559_,10.46880044,-0.434143852,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,8703,DB00678,10007559,156,15443,129,10595,0.129588454,0.829678766,0.651945317,1.057350271,0.255072077,DB0067810007559_,1.366209119,-0.186716682,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,losartan,DB00678
,8704,DB01060,10007559,45,8542,20,5061,0.306031089,1.333062421,0.770165204,2.385899617,0.472927696,DB0106010007559_,0.748812766,0.287478867,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,amoxicillin,DB01060
,8705,DB00476,10028813,2206,15051,639,5538,3.61172936580302e-07,1.270201169,1.156365593,1.396673004,5.77283711645681e-06,DB0047610028813_,12.0623469,0.239175289,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,8706,DB00557,10028813,445,5542,121,2946,2.22184286768115e-11,1.954841,1.587146753,2.422395009,8.02764807931259e-10,DB0055710028813_,20.94295934,0.67030886,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,hydroxyzine,DB00557
,8707,DB14509,10028813,55,830,28,523,0.416445844,1.237547244,0.760351439,2.054106419,0.58568566,DB1450910028813_,0.53497205,0.213131392,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lithium carbonate,DB14509
,8709,DB01060,10012735,534,8053,286,4795,0.167953117,1.111760785,0.956803294,1.293770072,0.308091819,DB0106010012735_,1.177357427,0.105945051,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,8714,DB00555,10002368,35,7012,29,3457,0.045020753,0.595030923,0.352690533,1.011010671,0.115603039,DB0055510002368_,2.157593037,-0.519141903,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,8715,DB00555,10022998,52,6995,48,3438,0.001894523,0.532463618,0.351907054,0.807193565,0.009303602,DB0055510022998_,4.677353622,-0.630240707,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,8717,DB01267,10053762,313,2539,373,3342,0.222320321,1.104516459,0.939002944,1.298650522,0.376405129,DB0126710053762_,0.977089244,0.099407645,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,paliperidone,DB01267
,8719,DB00497,10033295,335,18932,308,16067,0.31840716,0.923070931,0.787210875,1.082651942,0.486379353,DB0049710033295_,0.720766397,-0.0800492,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,8723,DB00230,10037844,363,19311,136,8515,0.116534555,1.176904026,0.962116417,1.446517002,0.23594152,DB0023010037844_,1.4441713,0.162887283,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,8724,DB00316,10001053,221,65253,194,36759,9.77513367730027e-06,0.64170526,0.526552333,0.782616735,0.000106481,DB0031610001053_,9.147541129,-0.443626177,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,8725,DB00316,10010071,343,65131,150,36803,0.008467926,1.292118971,1.063013338,1.576725126,0.031167041,DB0031610010071_,3.468394121,0.256283484,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,8726,DB00316,10022523,686,64788,334,36619,0.025885226,1.160911026,1.016431294,1.327910855,0.075439977,DB0031610022523_,2.584417943,0.149205064,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,8727,DB00316,10027417,426,65048,211,36742,0.125709974,1.1404164,0.964159033,1.352137544,0.249653332,DB0031610027417_,1.387681997,0.131393459,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,8729,DB00316,10042464,379,65095,157,36796,0.000980167,1.364555597,1.129464466,1.654887315,0.005415385,DB0031610042464_,5.218511244,0.310828806,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,8730,DB00331,10000081,398,24548,293,20459,0.114481252,1.132078805,0.969946489,1.322594763,0.232851482,DB0033110000081_,1.457354443,0.124055593,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,8731,DB01261,10000081,81,3700,81,3222,0.425746841,0.870829029,0.629585329,1.204495745,0.594478244,DB0126110000081_,0.520071159,-0.138309614,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,sitagliptin,DB01261
,8732,DB06655,10000081,103,3585,66,2053,0.516625871,0.893723088,0.646528569,1.242671793,0.676287309,DB0665510000081_,0.39113728,-0.112359296,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,liraglutide,DB06655
,8734,DB00213,10037855,40,18855,23,13398,0.445235024,1.235784185,0.721786751,2.163244165,0.613252423,DB0021310037855_,0.488978645,0.211705737,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,8739,DB00695,10037855,47,28002,34,20494,1,1.011711556,0.636767967,1.622737158,1,DB0069510037855_,0,0.011643507,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,8741,DB00904,10037855,45,23024,22,14434,0.380301061,1.282290421,0.753724562,2.243460251,0.550376511,DB0090410037855_,0.597152669,0.24864787,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,8751,DB08932,10035664,1936,17507,561,6036,0.000491491,1.18979671,1.077542315,1.31526721,0.003050495,DB0893210035664_,5.792451539,0.17378246,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,macitentan,DB08932
,8752,DB00203,10011906,1344,12534,736,8202,0.000196518,1.194938169,1.08669346,1.314709629,0.001420064,DB0020310011906_,6.557053535,0.178094443,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,8753,DB01240,10011906,693,5058,219,1357,0.052577122,0.849014263,0.719547772,1.004458641,0.129861835,DB0124010011906_,2.041284199,-0.163679293,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,8754,DB00203,10020100,72,13806,17,8921,7.1184728240932e-05,2.736584493,1.595175948,4.956878784,0.00059532,DB0020310020100_,7.426411577,1.006710608,female,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,8756,DB00203,10042609,49,13829,23,8915,0.227941714,1.373386925,0.82025536,2.36356062,0.383306472,DB0020310042609_,0.958920422,0.317279897,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,8758,DB00203,10061599,39,13839,14,8924,0.066475575,1.796305975,0.953468769,3.584023148,0.155006474,DB0020310061599_,1.864288394,0.58573232,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,8760,DB06643,10003246,266,52155,17,7498,0.00041344,2.249461043,1.377495608,3.922097018,0.002632834,DB0664310003246_,5.939694462,0.810690651,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,8761,DB06643,10003285,169,52252,16,7499,0.1194506,1.515878052,0.906087236,2.714424126,0.240502415,DB0664310003285_,1.425025147,0.415994843,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,8762,DB06643,10033775,302,52119,40,7475,0.682822241,1.082845891,0.776036662,1.547530136,0.80823104,DB0664310033775_,0.212907321,0.07959266,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,8764,DB00472,10002855,337,10422,121,4191,0.318467371,1.119970775,0.904270593,1.394621722,0.486440704,DB0047210002855_,0.720640267,0.113302591,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,8765,DB01238,10002855,204,5046,134,3368,0.909933491,1.016131063,0.809452279,1.278919085,0.959486584,DB0123810002855_,0.041356946,0.01600234,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,8766,DB00472,10053762,340,10419,159,4153,0.106963174,0.852375436,0.701472627,1.039219477,0.221563262,DB0047210053762_,1.507047122,-0.159728196,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,8767,DB01238,10053762,382,4868,328,3174,0.000503566,0.759393797,0.649005037,0.888877035,0.003108405,DB0123810053762_,5.77364565,-0.275234799,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole,DB01238
,8768,DB09068,10037844,77,2318,13,973,0.001372068,2.485718984,1.363154028,4.901980137,0.007144042,DB0906810037844_,4.941476544,0.910561947,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,vortioxetine,DB09068
,8769,DB00005,10011469,195,127887,18,42401,1.37566479140233e-09,3.591884683,2.213287516,6.189089451,3.72009763806691e-08,DB0000510011469_,17.10693083,1.278677046,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,8770,DB00005,10033546,65,128017,16,42403,0.367606491,1.345600664,0.76959922,2.491979115,0.537300115,DB0000510033546_,0.621198467,0.296840504,NA,10033546,Pallor,10047065,Vascular disorders,Vasc,etanercept,DB00005
,8778,DB00338,10013916,65,33609,17,22255,0.00039462,2.531789623,1.466217767,4.608331352,0.002533918,DB0033810013916_,5.977988482,0.928926413,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,8780,DB00515,10013709,48,1822,60,2091,0.696389275,0.918161334,0.611397898,1.372402397,0.817351734,DB0051510013709_,0.201685758,-0.085382159,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cisplatin,DB00515
,8781,DB00531,10013709,223,7029,221,6295,0.310354239,0.903687396,0.744492305,1.096946906,0.477782662,DB0053110013709_,0.738599332,-0.10127178,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,8782,DB00541,10013709,88,3046,103,4194,0.298727995,1.17633971,0.871345536,1.585330689,0.464720053,DB0054110013709_,0.766320092,0.162407677,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,vincristine,DB00541
,8783,DB00773,10013709,100,2223,99,2728,0.146321154,1.23950822,0.923812193,1.663263595,0.278800402,DB0077310013709_,1.277259159,0.214714704,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,etoposide,DB00773
,8784,DB00958,10013709,100,4494,74,2511,0.078371455,0.755111852,0.551175116,1.038402353,0.175654974,DB0095810013709_,1.739233583,-0.280889393,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,8785,DB00515,10053762,162,1708,173,1978,0.492679867,1.084421891,0.861156677,1.365109655,0.655556268,DB0051510053762_,0.422271139,0.081047026,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cisplatin,DB00515
,8786,DB00531,10053762,405,6847,372,6144,0.767368467,0.976925097,0.842907118,1.132487135,0.872190614,DB0053110053762_,0.136747285,-0.023345296,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclophosphamide,DB00531
,8787,DB00541,10053762,159,2975,195,4102,0.294944819,1.124251695,0.901080602,1.401022105,0.460862239,DB0054110053762_,0.774656112,0.117117654,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,vincristine,DB00541
,8788,DB00773,10053762,207,2116,220,2607,0.155039581,1.159203103,0.945755376,1.420451631,0.290827145,DB0077310053762_,1.235026191,0.147732789,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,etoposide,DB00773
,8789,DB00958,10053762,334,4260,236,2349,0.005533045,0.780427878,0.653498692,0.933028002,0.022181969,DB0095810053762_,3.808475549,-0.247912949,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,carboplatin,DB00958
,8795,DB09068,10028813,437,1958,108,878,7.89728128190738e-08,1.814131538,1.443418171,2.294584592,1.46131670886966e-06,DB0906810028813_,13.43617267,0.595606862,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,vortioxetine,DB09068
,8796,DB09068,10047700,157,2238,64,922,1,1.010623057,0.74290754,1.387831724,1,DB0906810047700_,0,0.010567029,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,vortioxetine,DB09068
,8814,DB00441,10043554,138,2136,95,1799,0.155006672,1.223387796,0.927877148,1.61843943,0.290796544,DB0044110043554_,1.235131418,0.201623892,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,gemcitabine,DB00441
,8815,DB00515,10043554,86,1784,73,2078,0.051862795,1.372108633,0.985985888,1.91364372,0.128544419,DB0051510043554_,2.051480762,0.316348705,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,cisplatin,DB00515
,8818,DB00682,10019909,34,19425,30,16334,0.900303559,0.952969831,0.565714822,1.612885175,0.956698706,DB0068210019909_,0.044266769,-0.048172033,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,8823,DB00370,10001497,51,4490,38,3625,0.748505386,1.083563391,0.696289379,1.69912997,0.857219096,DB0037010001497_,0.154061739,0.080255046,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,mirtazapine,DB00370
,8824,DB01238,10001497,76,5174,97,3405,1.99555849352784e-05,0.51565301,0.375586317,0.705844534,0.000199404,DB0123810001497_,8.520177015,-0.662321201,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,8825,DB09068,10001497,33,2362,17,969,0.436780282,0.796387557,0.428667562,1.532179107,0.605318309,DB0906810001497_,0.502000829,-0.227669331,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,vortioxetine,DB09068
,8827,DB09068,10019211,119,2276,34,952,0.055926131,1.463831819,0.984214403,2.228047001,0.135955455,DB0906810019211_,1.995427981,0.381057531,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,vortioxetine,DB09068
,8836,DB00921,10045555,25,5820,52,4851,0.000124275,0.400755351,0.237911585,0.658719188,0.000960473,DB0092110045555_,6.948084873,-0.914404135,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,buprenorphine,DB00921
,8842,DB01238,10028813,253,4997,90,3412,5.73415584827283e-08,1.919311489,1.496937902,2.47924188,1.09258634629831e-06,DB0123810028813_,13.72696288,0.651966522,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,aripiprazole,DB01238
,8843,DB01238,10047700,145,5105,55,3447,0.00024385,1.78001199,1.292291251,2.481971999,0.001698287,DB0123810047700_,6.378135233,0.5766201,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,aripiprazole,DB01238
,8845,DB00581,10000081,62,2051,68,2001,0.533577687,0.889562796,0.616598652,1.281368678,0.690262052,DB0058110000081_,0.370683968,-0.117025177,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,lactulose,DB00581
,8846,DB01069,10000081,204,6496,43,2352,0.000949181,1.717676131,1.226522401,2.454078597,0.00527635,DB0106910000081_,5.244520786,0.540972291,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,promethazine,DB01069
,8847,DB01234,10000081,377,31248,278,32610,1.2437209991317e-05,1.41520851,1.207893518,1.659752723,0.000131369,DB0123410000081_,8.937499458,0.347276877,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,8849,DB00338,10009887,120,33554,85,22187,0.668130202,0.933506572,0.700790388,1.248145457,0.798390761,DB0033810009887_,0.225157126,-0.068807276,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,8852,DB01234,10009887,129,31496,146,32742,0.506329283,0.918540085,0.718733526,1.172623581,0.667144479,DB0123410009887_,0.404748646,-0.084969734,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,8854,DB00581,10012735,128,1985,116,1953,0.553023272,1.085615791,0.831038956,1.419397951,0.70667072,DB0058110012735_,0.347190464,0.082147375,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lactulose,DB00581
,8855,DB01069,10012735,445,6255,144,2251,0.309678363,1.112089549,0.913614164,1.35993576,0.477119415,DB0106910012735_,0.739988473,0.106240723,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,promethazine,DB01069
,8857,DB00581,10037660,66,2047,71,1998,0.602755927,0.90734932,0.635177543,1.294638518,0.746568874,DB0058110037660_,0.292267404,-0.097227765,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,lactulose,DB00581
,8858,DB01234,10037660,744,30881,896,31992,0.002898789,0.860233471,0.778504466,0.950335252,0.013139208,DB0123410037660_,4.33215452,-0.150551449,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,8859,DB06769,10037660,56,611,91,965,0.929525891,0.971938747,0.673225277,1.393450778,0.970974544,DB0676910037660_,0.029455027,-0.028462494,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,bendamustine,DB06769
,8860,DB00181,10008479,113,9743,40,5831,0.004151474,1.690655092,1.167343241,2.493249965,0.017603081,DB0018110008479_,4.039681341,0.525116082,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,8861,DB00181,10016256,587,9269,221,5650,1.00739623874016e-09,1.619005671,1.379521626,1.905285284,2.79761332649605e-08,DB0018110016256_,17.39191407,0.481812178,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,8862,DB00181,10019211,469,9387,173,5698,1.64969948815223e-08,1.645542116,1.374825507,1.976661571,3.51824349258266e-07,DB0018110019211_,14.86013379,0.498069884,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,8863,DB00181,10041466,58,9798,19,5852,0.024248406,1.823163721,1.068800575,3.245415092,0.071820312,DB0018110041466_,2.633587946,0.6005733,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,8865,DB00181,10070863,276,9580,227,5644,0.000301397,0.716353773,0.59686765,0.860388,0.002025883,DB0018110070863_,6.201749655,-0.333581137,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,8869,DB00531,10020642,39,7213,31,6485,0.633064467,1.131075603,0.686822937,1.877267861,0.771750551,DB0053110020642_,0.259093901,0.123169041,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,cyclophosphamide,DB00531
,8871,DB01229,10020642,39,5702,24,2685,0.342679256,0.765187719,0.447696749,1.333137395,0.511968867,DB0122910020642_,0.669491463,-0.267634092,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,paclitaxel,DB01229
,8872,DB00531,10033371,144,7108,69,6447,1.14729050800134e-05,1.892790725,1.407986846,2.565250237,0.000122364,DB0053110033371_,9.008512895,0.638052314,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,8873,DB00997,10033371,139,5192,33,3481,8.65926347719603e-09,2.823713554,1.915098063,4.272800488,1.97491314965811e-07,DB0099710033371_,15.43757123,1.038052882,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,8874,DB01229,10033371,182,5559,69,2640,0.130734152,1.252578145,0.94052734,1.684219872,0.256798719,DB0122910033371_,1.359462694,0.225203943,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,8875,DB00997,10047700,259,5072,143,3371,0.085204412,1.203729739,0.972891818,1.493996794,0.187082947,DB0099710047700_,1.676203194,0.185424852,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,doxorubicin,DB00997
,8876,DB00531,10050528,69,7183,17,6499,1.71402999044101e-07,3.671848206,2.133401185,6.668551691,2.95819292834812e-06,DB0053110050528_,12.73093197,1.300695134,female,10050528,Ejection fraction decreased,10022891,Investigations,Inv,cyclophosphamide,DB00531
,8877,DB00997,10050528,83,5248,20,3494,1.57717749625756e-05,2.762671436,1.676017879,4.763328848,0.000161843,DB0099710050528_,8.7288832,1.016198123,female,10050528,Ejection fraction decreased,10022891,Investigations,Inv,doxorubicin,DB00997
,8882,DB09068,10037087,146,2249,17,969,5.39542640376787e-09,3.699037147,2.21726158,6.561887284,1.28575505913906e-07,DB0906810037087_,15.86674951,1.308072555,female,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,vortioxetine,DB09068
,8883,DB00047,10013968,393,8892,283,8235,0.001671294,1.286065892,1.097669668,1.508279479,0.008395596,DB0004710013968_,4.780048044,0.251587862,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,8884,DB00331,10013968,876,24070,638,20114,0.00935887,1.147371859,1.033099249,1.274774037,0.033760778,DB0033110013968_,3.388455558,0.137473987,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,8885,DB00341,10013968,583,10822,211,4857,0.008282643,1.240022923,1.053552853,1.463836166,0.030618635,DB0034110013968_,3.486146473,0.215129866,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,8886,DB00370,10013968,164,4377,129,3534,0.857625033,1.026464908,0.806404051,1.308733204,0.931784979,DB0037010013968_,0.0706532,0.026120771,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mirtazapine,DB00370
,8887,DB01306,10013968,224,3984,172,3694,0.071141077,1.207498175,0.980303271,1.489402957,0.163285296,DB0130610013968_,1.812256329,0.188550595,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin aspart,DB01306
,8888,DB08932,10013968,4628,14815,1435,5162,0.000660421,1.123737132,1.050316534,1.202685825,0.003905761,DB0893210013968_,5.545302563,0.116659856,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,8889,DB09068,10013573,90,2305,38,948,0.921075476,0.974090636,0.654242655,1.474726326,0.965021878,DB0906810013573_,0.035604506,-0.026250924,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,vortioxetine,DB09068
,8890,DB01050,10047700,650,17458,274,9097,0.003775904,1.236081234,1.069195486,1.432078979,0.016281106,DB0105010047700_,4.117749968,0.21194608,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,8891,DB01050,10053762,407,17701,190,9181,0.239013079,1.111056038,0.931191377,1.329402839,0.396751266,DB0105010053762_,0.924445728,0.105310949,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,8892,DB00331,10021143,83,24863,70,20682,0.9353779,0.986320859,0.708530348,1.376415204,0.975593044,DB0033110021143_,0.024709743,-0.013773562,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,8904,DB01060,10053762,149,8438,100,4981,0.32184916,0.879567554,0.676428973,1.147730137,0.490156078,DB0106010053762_,0.713031411,-0.128324908,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,amoxicillin,DB01060
,8907,DB01076,10054889,35,25712,43,25540,0.366480009,0.80851348,0.502152024,1.293780132,0.536082852,DB0107610054889_,0.623466556,-0.212557927,NA,10054889,Transaminases increased,10022891,Investigations,Inv,atorvastatin,DB01076
,8910,DB00927,10061818,119,7378,74,4942,0.657249986,1.077164724,0.797248816,1.463351479,0.79052856,DB0092710061818_,0.235053494,0.074332334,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,8912,DB01222,10061818,50,9224,34,5371,0.49734349,0.856317004,0.542194432,1.367247028,0.659519896,DB0122210061818_,0.416243138,-0.15511464,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,8913,DB01590,10061818,212,4526,53,2814,3.67519428898227e-10,2.486693291,1.825248447,3.439901513,1.10276805805821e-08,DB0159010061818_,18.32285731,0.910953833,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,8914,DB01065,10012378,119,4212,45,3006,0.000212267,1.887113155,1.324008447,2.730999872,0.001513891,DB0106510012378_,6.493072385,0.63504823,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,melatonin,DB01065
,8915,DB01238,10012378,237,5013,122,3380,0.017953238,1.309767538,1.043606658,1.650426935,0.056748937,DB0123810012378_,2.869118346,0.26984967,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,8916,DB01065,10042458,48,4283,19,3032,0.03371229,1.788278999,1.029314843,3.228465351,0.092797943,DB0106510042458_,2.377330808,0.581253704,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,melatonin,DB01065
,8917,DB01238,10042458,167,5083,111,3391,1,1.003693257,0.781557159,1.292974116,1,DB0123810042458_,0,0.003686453,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,8919,DB01238,10042464,78,5172,59,3443,0.48248415,0.880093289,0.617739935,1.259602325,0.64686419,DB0123810042464_,0.435618914,-0.127727367,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,8923,DB06605,10012735,755,13318,438,12595,7.40078370445546e-16,1.630128522,1.44344819,1.842615237,5.02011870120288e-14,DB0660510012735_,30.62273772,0.488658859,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,8928,DB00678,10001480,31,15568,31,10693,0.154711357,0.686882351,0.403577543,1.169088696,0.290379751,DB0067810001480_,1.236565727,-0.375592251,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,losartan,DB00678
,8929,DB00682,10001480,25,19434,33,16331,0.088172261,0.636630317,0.362776913,1.104190333,0.192212969,DB0068210001480_,1.649151308,-0.451566141,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,8930,DB00695,10001480,55,27994,63,20465,0.015259239,0.638236781,0.436088104,0.931642753,0.049974996,DB0069510001480_,2.99623248,-0.449045935,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,8931,DB00722,10001480,56,25347,80,25952,0.05888649,0.716715394,0.499826973,1.021589486,0.141373831,DB0072210001480_,1.956347616,-0.333076457,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,8934,DB08828,10001480,58,704,123,1019,0.020928462,0.68266739,0.483385225,0.955225451,0.064062491,DB0882810001480_,2.747896246,-0.381747522,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,vismodegib,DB08828
,8935,DB00421,10010774,186,8717,81,5171,0.021259183,1.362154207,1.041314452,1.79502167,0.064893465,DB0042110010774_,2.735008355,0.309067422,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,8937,DB00678,10010774,301,15298,217,10507,0.588239381,0.952714175,0.79600719,1.1417415,0.735194338,DB0067810010774_,0.307620409,-0.048440342,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,8938,DB00682,10010774,356,19103,244,16120,0.013135275,1.231177687,1.041730166,1.457064897,0.044255682,DB0068210010774_,3.117771519,0.20797118,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,8939,DB00695,10010774,573,27476,429,20099,0.722356743,0.9770457,0.859453208,1.111398325,0.836493468,DB0069510010774_,0.178536567,-0.023221852,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,8940,DB00722,10010774,395,25008,371,25661,0.229692627,1.092474332,0.944696973,1.263617416,0.385571459,DB0072210010774_,0.953028735,0.088445153,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,8942,DB01136,10010774,166,9718,170,10945,0.408679428,1.099754788,0.881008172,1.372567717,0.57808171,DB0113610010774_,0.548040054,0.095087235,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,8943,DB08828,10010774,17,745,55,1087,0.004465823,0.45115546,0.243462226,0.796519174,0.018662026,DB0882810010774_,3.981264495,-0.795943298,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,vismodegib,DB08828
,8944,DB00421,10011224,303,8600,111,5141,8.33824930628882e-06,1.631752989,1.304868097,2.052650277,9.27314927081877e-05,DB0042110011224_,9.285802416,0.48965489,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,8946,DB00678,10011224,382,15217,226,10498,0.072579189,1.166056191,0.984718673,1.383342182,0.16581182,DB0067810011224_,1.796901747,0.153627278,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,8947,DB00682,10011224,737,18722,303,16061,1.91025225768738e-28,2.086528525,1.819741156,2.397325374,3.81832552040402e-26,DB0068210011224_,58.52740044,0.735501692,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,8948,DB00695,10011224,834,27215,404,20124,2.28796187768821e-12,1.5264632,1.351884881,1.725692298,9.73124238754604e-11,DB0069510011224_,23.05309445,0.422953426,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,8950,DB01136,10011224,206,9678,194,10921,0.076723241,1.198222654,0.978115919,1.468318378,0.172741479,DB0113610011224_,1.755959141,0.180839337,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,8953,DB00678,10013911,86,15513,62,10662,0.801515171,0.953371032,0.679129865,1.344935906,0.892609946,DB0067810013911_,0.113605584,-0.04775112,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,losartan,DB00678
,8954,DB00682,10013911,77,19382,65,16299,1,0.996184341,0.706255801,1.408873005,1,DB0068210013911_,0,-0.003822957,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,8955,DB00722,10013911,147,25256,145,25887,0.769296616,1.039132748,0.819892477,1.317126332,0.873663127,DB0072210013911_,0.135060416,0.038386469,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,8956,DB01136,10013911,46,9838,51,11064,1,1.01436347,0.665201,1.54299576,1,DB0113610013911_,0,0.014261292,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,8957,DB08828,10013911,80,682,122,1020,0.939518475,0.980730756,0.718023214,1.333978813,0.978959927,DB0882810013911_,0.02126457,-0.019457316,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,vismodegib,DB08828
,8958,DB00555,10037844,207,6840,95,3391,0.576727513,1.080233683,0.840148022,1.397164539,0.725945429,DB0055510037844_,0.320280434,0.077177391,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,lamotrigine,DB00555
,8961,DB00319,10043554,49,1343,76,1777,0.408434489,0.8531328,0.578994184,1.247131796,0.577839818,DB0031910043554_,0.54845858,-0.158840057,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,piperacillin,DB00319
,8962,DB01118,10043554,34,3029,39,4670,0.229159424,1.344023807,0.821026235,2.190603823,0.384891749,DB0111810043554_,0.954793156,0.295667955,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,amiodarone,DB01118
,8965,DB00319,10070863,39,1353,32,1821,0.039930691,1.640024771,0.995454913,2.719884174,0.105537107,DB0031910070863_,2.248692666,0.494711346,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,piperacillin,DB00319
,8966,DB01118,10070863,121,2942,140,4569,0.020400733,1.342179842,1.038779497,1.732190945,0.062772404,DB0111810070863_,2.768239732,0.29429504,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,amiodarone,DB01118
,8968,DB01592,10011906,203,6073,207,2860,4.16405028075479e-14,0.461870664,0.37669965,0.566251971,2.23371554346203e-12,DB0159210011906_,26.82735475,-0.772470374,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,8969,DB00126,10028735,77,10094,26,5919,0.013798173,1.736554523,1.099068789,2.826330102,0.046014335,DB0012610028735_,3.078802301,0.551902991,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,8970,DB01373,10028735,145,22575,25,7356,0.002262571,1.889781705,1.229132354,3.019041038,0.010756134,DB0137310028735_,4.532279126,0.636461322,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,8971,DB08932,10028735,927,18516,222,6375,9.59015451124626e-07,1.437600909,1.236887709,1.676648452,1.37935546554368e-05,DB0893210028735_,11.19130913,0.362975689,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,8972,DB00316,10000097,46,65428,18,36935,0.195684155,1.442640898,0.820317143,2.644010418,0.34387819,DB0031610000097_,1.067467784,0.366475391,NA,10000097,Abdominal tenderness,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,8981,DB00207,10028334,117,8963,48,5407,0.02370297,1.470403569,1.040399051,2.106575621,0.070542637,DB0020710028334_,2.651537966,0.3855369,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,azithromycin,DB00207
,8987,DB00207,10055798,207,8873,8,5447,1.71838712925292e-32,15.88296057,7.903983323,37.30496624,4.47205996954584e-30,DB0020710055798_,67.57970364,2.765246872,female,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,azithromycin,DB00207
,8997,DB00472,10040108,91,10668,190,4122,1.60772349784845e-42,0.185083595,0.142145438,0.239504615,6.9277069083519e-40,DB0047210040108_,90.16787485,-1.68694769,male,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,8998,DB00996,10040108,81,38872,58,22367,0.217141805,0.803592939,0.566306426,1.146490088,0.370068881,DB0099610040108_,0.994066126,-0.218662432,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,8999,DB01224,10040108,36,8072,47,5870,0.009940615,0.557044316,0.350078016,0.879682038,0.035390634,DB0122410040108_,3.341308057,-0.58511048,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,9002,DB01238,10001540,95,5155,79,3423,0.159332124,0.79852881,0.584286169,1.09383182,0.296614248,DB0123810001540_,1.215322813,-0.224984231,NA,10001540,Akathisia,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,9003,DB00555,10003549,128,6919,73,3413,0.326072701,0.864948408,0.641841069,1.172955604,0.494608359,DB0055510003549_,0.703989024,-0.145085418,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,9004,DB01238,10003549,94,5156,51,3451,0.266451449,1.233603558,0.865630434,1.775529726,0.428595333,DB0123810003549_,0.847242084,0.209939608,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,9005,DB00555,10013496,47,7000,18,3468,0.427785263,1.2936354,0.735931501,2.370258099,0.596354496,DB0055510013496_,0.516919997,0.257456394,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,9006,DB01238,10013496,36,5214,30,3472,0.379132774,0.799108293,0.477540632,1.346023096,0.549154403,DB0123810013496_,0.599375632,-0.224258807,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,9007,DB00555,10013573,294,6753,129,3357,0.268072645,1.132956192,0.914013972,1.410483209,0.430511432,DB0055510013573_,0.842781399,0.124830316,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,9008,DB01238,10013573,155,5095,77,3425,0.035067055,1.353139475,1.019338932,1.808676643,0.095531692,DB0123810013573_,2.348297233,0.302427429,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,9011,DB00555,10016256,345,6702,128,3358,0.004331796,1.350434699,1.094475062,1.674554463,0.018223633,DB0055510016256_,4.005036007,0.30042654,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,9012,DB01238,10016256,224,5026,107,3395,0.003509894,1.414049461,1.113341877,1.805109793,0.015353231,DB0123810016256_,4.17642936,0.346457546,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,9013,DB01238,10019211,186,5064,55,3447,1.51800764319238e-08,2.301746377,1.689613121,3.179293782,3.27055990994358e-07,DB0123810019211_,14.93313445,0.833668129,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,9016,DB00555,10027175,90,6957,52,3434,0.370297256,0.854336622,0.599033282,1.229404294,0.539956916,DB0055510027175_,0.616265928,-0.157429992,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,9017,DB01238,10027175,69,5181,28,3474,0.02815686,1.652278199,1.048369524,2.668885261,0.080593991,DB0123810027175_,2.518331184,0.502155062,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,9018,DB00555,10028411,75,6972,24,3462,0.0677247,1.551682943,0.966578577,2.57492771,0.15723644,DB0055510028411_,1.850004619,0.439340112,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lamotrigine,DB00555
,9019,DB01238,10028411,45,5205,19,3483,0.09689985,1.584782158,0.906567674,2.874181003,0.206110667,DB0123810028411_,1.579342038,0.460446958,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,aripiprazole,DB01238
,9020,DB00555,10028813,359,6688,112,3374,7.72296465879422e-06,1.616988296,1.298804521,2.02562704,8.66032960991493e-05,DB0055510028813_,9.354172682,0.480565343,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lamotrigine,DB00555
,9029,DB00555,10047513,84,6963,36,3450,0.49615365,1.156083838,0.771853206,1.763073165,0.658473513,DB0055510047513_,0.417830982,0.145038292,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,lamotrigine,DB00555
,9030,DB01238,10047513,46,5204,23,3479,0.269637119,1.337004837,0.792240737,2.315519447,0.432211958,DB0123810047513_,0.838839168,0.290431916,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,aripiprazole,DB01238
,9039,DB00065,10012735,180,9284,99,4858,0.702749993,0.951396162,0.738454079,1.231609607,0.821680282,DB0006510012735_,0.196403911,-0.049824729,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,infliximab,DB00065
,9040,DB00437,10012735,442,6479,581,10965,0.00011447,1.287456353,1.130716388,1.465231029,0.000895716,DB0043710012735_,7.017886776,0.252668452,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,9041,DB00860,10012735,108,1775,61,1435,0.031717404,1.431203994,1.027527059,2.008441874,0.088474154,DB0086010012735_,2.425044817,0.358516044,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,prednisolone,DB00860
,9042,DB01033,10012735,60,1122,58,1246,0.508783391,1.14874495,0.779728907,1.693478362,0.66932116,DB0103310012735_,0.401491275,0.138669998,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,mercaptopurine,DB01033
,9043,DB00065,10013709,1730,7734,640,4317,4.91679059063458e-17,1.508799498,1.366812939,1.666915657,3.77336761094394e-15,DB0006510013709_,33.21080853,0.4113143,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,9044,DB00437,10013709,148,6773,305,11241,0.034509026,0.805380389,0.655711942,0.98567237,0.094437247,DB0043710013709_,2.35981972,-0.21644058,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,9045,DB00860,10013709,117,1766,97,1399,0.776255154,0.955510711,0.716895112,1.2758934,0.877982174,DB0086010013709_,0.130128988,-0.045509306,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,prednisolone,DB00860
,9046,DB01033,10013709,51,1131,46,1258,0.350825535,1.23308303,0.804391231,1.894694747,0.520559383,DB0103310013709_,0.652851308,0.209517562,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,mercaptopurine,DB01033
,9048,DB00437,10024384,19,6902,33,11513,1,0.960401822,0.515510979,1.740713843,1,DB0043710024384_,0,-0.040403517,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,allopurinol,DB00437
,9051,DB00065,10037660,126,9338,96,4861,0.006666293,0.683230726,0.51852186,0.902712989,0.025773945,DB0006510037660_,3.658391172,-0.380922664,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,9052,DB01033,10037660,97,1085,136,1168,0.062768198,0.76787946,0.577794172,1.017554034,0.148622834,DB0103310037660_,1.906343498,-0.264122511,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,mercaptopurine,DB01033
,9057,DB08865,10016256,84,1127,50,921,0.088642526,1.372720928,0.944863218,2.011539301,0.192998037,DB0886510016256_,1.645075261,0.316794849,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,crizotinib,DB08865
,9059,DB08865,10047700,104,1107,59,912,0.027091985,1.451960303,1.031578377,2.059264186,0.078219915,DB0886510047700_,2.548230996,0.372914576,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,crizotinib,DB08865
,9060,DB00175,10033645,32,8099,30,6076,0.44062785,0.800248369,0.470352208,1.364841339,0.60894887,DB0017510033645_,0.496020972,-0.222833138,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,9061,DB00203,10033645,38,13840,27,8911,0.7041108,0.906176432,0.538520131,1.54445174,0.822565564,DB0020310033645_,0.195327087,-0.098521255,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,9062,DB00331,10033645,286,24660,252,20500,0.513720839,0.943494207,0.79284159,1.12321485,0.673695227,DB0033110033645_,0.394977456,-0.058165054,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,9063,DB00374,10033645,40,17676,10,5714,0.620716909,1.293028823,0.634923204,2.901272175,0.761218215,DB0037410033645_,0.272835214,0.256987391,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,9067,DB00695,10033645,92,27957,54,20474,0.208782843,1.247682379,0.88168956,1.780778869,0.359869729,DB0069510033645_,1.022013176,0.221287733,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,9068,DB00761,10033645,59,15248,30,8595,0.740203356,1.108580358,0.702139522,1.78388103,0.850732192,DB0076110033645_,0.161657898,0.10308024,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,9073,DB00773,10071066,50,2273,21,2806,1.85793293035134e-05,2.938677066,1.727175793,5.167308765,0.000187218,DB0077310071066_,8.583237832,1.077959502,female,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,etoposide,DB00773
,9075,DB00987,10071066,35,2069,25,2903,0.011805682,1.964093927,1.138518789,3.434731156,0.040638077,DB0098710071066_,3.203049784,0.675031033,NA,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,cytarabine,DB00987
,9076,DB00997,10071066,74,5257,38,3476,0.24344879,1.287590258,0.857234572,1.962148584,0.401786422,DB0099710071066_,0.911834619,0.252772454,NA,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,doxorubicin,DB00997
,9079,DB01238,10047899,291,4959,147,3355,0.005028344,1.339243879,1.089035127,1.652512299,0.020556811,DB0123810047899_,3.884562938,0.292105185,NA,10047899,Weight increased,10022891,Investigations,Inv,aripiprazole,DB01238
,9080,DB00005,10031009,107,127975,29,42390,0.372660286,1.2221414,0.804259826,1.911661065,0.542394619,DB0000510031009_,0.611761463,0.200604566,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,9081,DB00005,10042674,1176,126906,300,42119,3.84232620285353e-05,1.30099855,1.144533429,1.482534812,0.000352577,DB0000510042674_,7.95024288,0.263132085,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,9082,DB00515,10000081,86,1784,40,2111,6.86231199759123e-07,2.543520379,1.71854019,3.820745409,1.02690504330592e-05,DB0051510000081_,11.486376,0.933549098,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,cisplatin,DB00515
,9084,DB00515,10013950,26,1844,52,2099,0.021430494,0.569221897,0.339702712,0.932660182,0.065302636,DB0051510013950_,2.728722874,-0.563484943,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,cisplatin,DB00515
,9087,DB00515,10021027,43,1827,12,2139,1.83318001886729e-06,4.194164723,2.164531484,8.76419333,2.4534183704647e-05,DB0051510021027_,10.61544316,1.433694208,female,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,cisplatin,DB00515
,9088,DB00515,10028116,53,1817,88,2063,0.031749578,0.683878746,0.474036084,0.978562024,0.088535717,DB0051510028116_,2.424349227,-0.379974649,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,cisplatin,DB00515
,9089,DB00515,10033371,70,1800,43,2108,0.001061412,1.906132495,1.27830114,2.870803969,0.005787016,DB0051510033371_,5.15213856,0.645076318,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,cisplatin,DB00515
,9097,DB14726,10002034,126,1891,161,2687,0.387943124,1.112014905,0.867032745,1.423744191,0.557995295,DB1472610002034_,0.583404749,0.106173599,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,dabigatran,DB14726
,9117,DB00047,10016322,126,9159,64,8454,9.89170192868919e-05,1.817141604,1.332524149,2.498967707,0.000789564,DB0004710016322_,7.144029817,0.597264719,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,9118,DB00222,10016322,58,3148,16,3112,9.57705947135651e-07,3.582567565,2.026635164,6.692972242,1.37784897758405e-05,DB0022210016322_,11.19240189,1.27607974,female,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,9119,DB00331,10016322,382,24564,193,20559,6.73994379824856e-09,1.656544407,1.388205919,1.981986859,1.56986639554243e-07,DB0033110016322_,15.66710513,0.50473375,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,9120,DB00471,10016322,228,13961,57,5408,0.0026748,1.549479584,1.152405205,2.113114558,0.012309747,DB0047110016322_,4.397363887,0.437919122,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,9121,DB01238,10016322,106,5144,46,3456,0.01517357,1.548102619,1.082229136,2.244768267,0.049768008,DB0123810016322_,3.000382901,0.437030064,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,9122,DB06700,10016322,130,2095,11,607,8.41660041221832e-06,3.423260263,1.835451763,7.074034222,9.34841926199698e-05,DB0670010016322_,9.277718199,1.23059339,female,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,desvenlafaxine,DB06700
,9123,DB00047,10027175,93,9192,45,8473,0.000306025,1.904937466,1.318942535,2.786883467,0.00205122,DB0004710027175_,6.18932065,0.644449182,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,9124,DB00222,10027175,33,3173,18,3110,0.048837145,1.796760597,0.980342691,3.396647716,0.122805352,DB0022210027175_,2.09715468,0.585985375,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,glimepiride,DB00222
,9125,DB00331,10027175,245,24701,119,20633,7.92472655534342e-07,1.719732134,1.374781265,2.161001988,1.16695483197312e-05,DB0033110027175_,11.35852782,0.542168543,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,metformin,DB00331
,9126,DB00471,10027175,140,14049,32,5433,0.006111759,1.691889094,1.143913641,2.571463036,0.024023866,DB0047110027175_,3.728707533,0.525845712,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,9132,DB01238,10039897,48,5202,42,3460,0.196356397,0.760182856,0.49068291,1.18163233,0.344610261,DB0123810039897_,1.065341178,-0.274196274,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,9135,DB08932,10000060,449,18994,153,6444,0.962201142,0.99562104,0.82502516,1.20676559,0.999741364,DB0893210000060_,0.000258669,-0.004388575,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,9136,DB08932,10030124,1065,18378,335,6262,0.218126335,1.08322325,0.953860986,1.232547029,0.371313432,DB0893210030124_,0.990708742,0.079941087,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,9137,DB08932,10042674,475,18968,144,6453,0.242420273,1.122195917,0.927300465,1.364775266,0.400636121,DB0893210042674_,0.914701693,0.115287406,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,9138,DB00264,10005750,398,29209,249,24643,0.000218532,1.34852037,1.147032615,1.587749714,0.001552884,DB0026410005750_,6.467641317,0.299007969,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,metoprolol,DB00264
,9139,DB00641,10005750,123,14001,102,12373,0.687422601,1.065684045,0.811997058,1.401062546,0.811574878,DB0064110005750_,0.208778625,0.063616889,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,simvastatin,DB00641
,9140,DB00695,10005750,231,27818,123,20405,0.004163823,1.377572179,1.101245298,1.729992891,0.017647431,DB0069510005750_,4.037165069,0.320322659,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,furosemide,DB00695
,9142,DB00264,10013573,1074,28533,773,24119,0.000803446,1.174451598,1.067982235,1.291921454,0.004590997,DB0026410013573_,5.383658063,0.160801314,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,9144,DB00695,10019211,1554,26495,425,20103,1.0272297367781e-87,2.774211021,2.486479554,3.100638734,1.63640809886136e-84,DB0069510019211_,192.9246442,1.02036639,female,10019211,Headache,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,9146,DB00264,10025482,875,28732,440,24452,9.47053169323736e-20,1.692382002,1.505448675,1.904482088,9.574343290644e-18,DB0026410025482_,39.18744473,0.526137005,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,9147,DB00641,10025482,425,13699,235,12240,3.45509008704738e-09,1.615861891,1.371971932,1.906746399,8.60417270848322e-08,DB0064110025482_,16.26843346,0.479868493,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,9148,DB00695,10025482,1078,26971,396,20132,1.4823989784247e-35,2.031901737,1.806431993,2.289184166,4.72301298762342e-33,DB0069510025482_,74.43286113,0.708972171,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,9158,DB00264,10047571,186,29421,92,24800,2.199105937419e-05,1.704174395,1.319657888,2.213536885,0.000216655,DB0026410047571_,8.437205273,0.533080768,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,metoprolol,DB00264
,9159,DB00641,10047571,94,14030,57,12418,0.026986714,1.45961959,1.038389552,2.067528402,0.077992236,DB0064110047571_,2.551145999,0.378175847,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,simvastatin,DB00641
,9160,DB00695,10047571,190,27859,71,20457,5.68886573414396e-07,1.965002056,1.487660472,2.620403365,8.69623936155708e-06,DB0069510047571_,11.65261988,0.675493292,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,furosemide,DB00695
,9162,DB00264,10047700,825,28782,475,24417,1.76383828838587e-11,1.47342313,1.312747741,1.655167482,6.46617704466146e-10,DB0026410047700_,21.15926587,0.387588353,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,9163,DB00641,10047700,424,13700,211,12264,1.8595988425577e-12,1.798804288,1.518567345,2.135853079,7.99992726295077e-11,DB0064110047700_,23.24900357,0.58712216,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,9164,DB00695,10047700,1055,26994,403,20125,1.0538453344145e-31,1.951669745,1.73582485,2.197875502,2.62562318626399e-29,DB0069510047700_,65.80964942,0.668685286,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,9169,DB00008,10019744,21,1504,49,1627,0.003407701,0.463747962,0.262833779,0.792208648,0.014994798,DB0000810019744_,4.200051939,-0.76841406,NA,10019744,Hepatitis C,10021881,Infections and infestations,Infec,peginterferon alfa-2a,DB00008
,9170,DB08934,10019744,98,4391,351,5853,5.060441230551e-20,0.372203,0.293415662,0.468580431,5.24708866844312e-18,DB0893410019744_,39.78885829,-0.988315874,NA,10019744,Hepatitis C,10021881,Infections and infestations,Infec,sofosbuvir,DB08934
,9173,DB00555,10013916,32,7015,18,3468,0.653733123,0.8788957,0.477881894,1.665586829,0.787753851,DB0055510013916_,0.23856961,-0.129089046,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,9174,DB01238,10013916,63,5187,28,3474,0.084738382,1.506872029,0.948971345,2.448492481,0.186318824,DB0123810013916_,1.680295967,0.410035998,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,9181,DB01195,10070863,107,1132,74,670,0.334593103,0.855889795,0.620340673,1.185775842,0.50373903,DB0119510070863_,0.685696943,-0.155613655,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,flecainide,DB01195
,9186,DB00046,10005169,43,5416,25,4667,0.142623341,1.482074478,0.883462949,2.536366159,0.273489295,DB0004610005169_,1.296492799,0.39344278,NA,10005169,Blindness,10015919,Eye disorders,Eye,insulin lispro,DB00046
,9187,DB00030,10005555,77,2129,50,1771,0.204618677,1.280963443,0.880482609,1.877989547,0.354623637,DB0003010005555_,1.03669823,0.247612484,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,insulin human,DB00030
,9188,DB00030,10005557,213,1993,230,1591,0.00282449,0.739353731,0.603545829,0.905358927,0.012865733,DB0003010005557_,4.353187824,-0.301978811,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,insulin human,DB00030
,9189,DB00030,10018484,41,2165,29,1792,0.546783643,1.170170004,0.706563792,1.960954689,0.701476831,DB0003010018484_,0.354567408,0.157149041,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,insulin human,DB00030
,9190,DB00046,10018484,97,5362,77,4615,0.645590774,1.084264132,0.793408367,1.485921919,0.7812598,DB0004610018484_,0.246847534,0.080901538,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,insulin lispro,DB00046
,9191,DB00030,10020772,35,2171,21,1800,0.280080427,1.381740651,0.779088833,2.50742361,0.443926261,DB0003010020772_,0.81209681,0.323344046,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,insulin human,DB00030
,9192,DB00046,10020772,78,5381,52,4640,0.15755469,1.293405605,0.89695984,1.878395247,0.294243137,DB0004610020772_,1.223348856,0.257278744,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,insulin lispro,DB00046
,9200,DB00557,10002757,38,5949,12,3055,0.176843552,1.626103595,0.830358181,3.423230454,0.319847223,DB0055710002757_,1.139911825,0.486186721,NA,10002757,Anticholinergic syndrome,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,9217,DB00813,10038661,39,10533,12,10156,0.000221848,3.133226429,1.606285236,6.576740887,0.001572198,DB0081310038661_,6.455280326,1.142063282,female,10038661,Respiratory acidosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,9227,DB01238,10024264,48,5202,40,3462,0.325248854,0.798644918,0.512754825,1.249822722,0.493629317,DB0123810024264_,0.705970415,-0.22483884,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,9228,DB00363,10067482,43,4585,47,6841,0.160349614,1.364994956,0.879661331,2.113403547,0.297964312,DB0036310067482_,1.210781559,0.311150734,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,clozapine,DB00363
,9229,DB00182,10047899,113,5081,41,2811,0.021495414,1.524701618,1.054378231,2.243020816,0.065447349,DB0018210047899_,2.72650929,0.421798731,NA,10047899,Weight increased,10022891,Investigations,Inv,amphetamine,DB00182
,9230,DB00715,10047899,91,4752,23,2264,0.006057343,1.884861901,1.178669137,3.1302559,0.023843844,DB0071510047899_,3.736229189,0.633854556,NA,10047899,Weight increased,10022891,Investigations,Inv,paroxetine,DB00715
,9231,DB01238,10044565,135,5115,77,3425,0.287366374,1.173921674,0.877694425,1.579526811,0.452260284,DB0123810044565_,0.793497416,0.160350002,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,9257,DB00005,10007697,180,127902,49,42370,0.251120175,1.216900477,0.882791796,1.705230214,0.41102786,DB0000510007697_,0.889094281,0.196307033,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,9259,DB00005,10067268,109,127973,39,42380,0.703568276,0.925552387,0.636546415,1.371062013,0.822205647,DB0000510067268_,0.195764736,-0.077364544,NA,10067268,Post procedural infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,9260,DB01609,10000059,43,1541,24,1319,0.106996912,1.533332836,0.904329978,2.656885016,0.221615683,DB0160910000059_,1.506810557,0.42744369,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,deferasirox,DB01609
,9261,DB08908,10012735,596,10077,132,3147,0.000381639,1.409993202,1.16062072,1.723083074,0.002465621,DB0890810012735_,6.00531165,0.343584883,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,9262,DB08908,10017944,195,10478,40,3239,0.019631317,1.506904645,1.065110254,2.17930581,0.060911193,DB0890810017944_,2.798338324,0.410057643,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,9263,DB00319,10012735,67,1325,44,1809,0.000188819,2.07850381,1.390021022,3.134624002,0.001373063,DB0031910012735_,6.590711359,0.731648313,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,piperacillin,DB00319
,9264,DB01590,10012735,360,4378,348,2519,7.98998389683255e-11,0.595288387,0.50807333,0.69746763,2.65005333411033e-09,DB0159010012735_,19.74868607,-0.518709307,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,everolimus,DB01590
,9268,DB00005,10008531,559,127523,130,42289,0.000202423,1.425929714,1.175829232,1.739961104,0.001456126,DB0000510008531_,6.531975561,0.354824032,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,9269,DB00005,10033433,161,127921,28,42391,0.000972681,1.905350849,1.269654675,2.957933087,0.005385909,DB0000510033433_,5.223969267,0.644666164,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,9270,DB00005,10044565,377,127705,108,42311,0.188870062,1.156542738,0.93115829,1.446409997,0.335131951,DB0000510044565_,1.093230942,0.145435156,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,9271,DB00005,10044755,98,127984,55,42364,0.002593065,0.58980258,0.419654483,0.836369788,0.01200536,DB0000510044755_,4.422402084,-0.527967409,NA,10044755,Tuberculosis,10021881,Infections and infestations,Infec,etanercept,DB00005
,9273,DB01238,10064355,38,5212,35,3467,0.18691278,0.722254245,0.443212257,1.180049277,0.332625771,DB0123810064355_,1.10073723,-0.325378062,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole,DB01238
,9274,DB00678,10021097,294,15305,230,10494,0.138634378,0.87645698,0.733649624,1.04801718,0.267871362,DB0067810021097_,1.317248407,-0.131867658,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,losartan,DB00678
,9275,DB00654,10007739,44,3772,25,2573,0.53807686,1.200497494,0.7167088,2.052355895,0.694101061,DB0065410007739_,0.365137708,0.182736049,NA,10007739,Cataract,10015919,Eye disorders,Eye,latanoprost,DB00654
,9277,DB00654,10047571,65,3751,33,2565,0.178431501,1.346852181,0.869961649,2.121040947,0.321877154,DB0065410047571_,1.133585316,0.297770152,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,latanoprost,DB00654
,9278,DB00177,10007559,55,4745,42,2808,0.244842133,0.774992399,0.507740181,1.190448074,0.403604494,DB0017710007559_,0.907319855,-0.254902057,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,valsartan,DB00177
,9279,DB00437,10007559,111,6810,187,11359,0.951974,0.990089627,0.774132931,1.261457769,0.990021368,DB0043710007559_,0.010028752,-0.009959807,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,allopurinol,DB00437
,9280,DB01067,10007559,71,4290,84,4739,0.68589217,0.933686328,0.669090769,1.299895116,0.810409763,DB0106710007559_,0.210215279,-0.068614735,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,glipizide,DB01067
,9281,DB01076,10007559,305,25442,317,25266,0.600005605,0.955475812,0.812990415,1.122801649,0.744519064,DB0107610007559_,0.295016821,-0.045545831,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,9282,DB01373,10007559,135,22585,59,7322,0.065032713,0.74181586,0.541790523,1.026341902,0.152494301,DB0137310007559_,1.880628055,-0.298654234,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,calcium,DB01373
,9285,DB00412,10028600,62,1002,83,1303,0.931215351,0.971390544,0.680178436,1.381342268,0.972293214,DB0041210028600_,0.02809786,-0.029026684,NA,10028600,Myocardial ischaemia,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,9290,DB00374,10024774,59,17657,18,5706,0.895013491,1.059217225,0.615481764,1.909987627,0.955976233,DB0037410024774_,0.045022227,0.057530168,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,9291,DB00559,10024774,63,9596,13,3293,0.112281865,1.662891711,0.904450111,3.298741408,0.229487875,DB0055910024774_,1.471905084,0.508558082,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,bosentan,DB00559
,9292,DB00682,10024774,77,19382,43,16321,0.034409957,1.507872215,1.024558043,2.245298276,0.094229902,DB0068210024774_,2.362017714,0.410699528,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,9293,DB00682,10064911,531,18928,144,16220,3.28702976420739e-40,3.159672456,2.620495172,3.830346855,1.2992417646946e-37,DB0068210064911_,84.9338676,1.150468369,female,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,9294,DB00575,10047899,107,5137,51,3778,0.011597682,1.542927447,1.092261197,2.204199143,0.040080863,DB0057510047899_,3.216856291,0.433681551,NA,10047899,Weight increased,10022891,Investigations,Inv,clonidine,DB00575
,9296,DB00321,10013710,117,7330,20,2830,0.00034311,2.258449123,1.394437627,3.840753711,0.002257199,DB0032110013710_,6.09363044,0.814678349,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,9297,DB01075,10013710,154,19794,104,10993,0.133472088,0.822391591,0.636381269,1.066275849,0.260627967,DB0107510013710_,1.344661301,-0.19553861,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,9298,DB00321,10022523,58,7389,31,2819,0.152518703,0.713823746,0.45280931,1.144992686,0.28750388,DB0032110022523_,1.246518924,-0.337119202,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,amitriptyline,DB00321
,9299,DB01075,10022523,186,19762,84,11013,0.125681621,1.234017176,0.947633745,1.618080219,0.249615884,DB0107510022523_,1.387832006,0.210274844,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,9300,DB01104,10022523,109,15354,41,7245,0.253533457,1.254422685,0.867506903,1.845210354,0.414044972,DB0110410022523_,0.881780682,0.226675455,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,9301,DB00321,10070863,472,6975,257,2593,3.38647901723966e-06,0.682785795,0.581312503,0.80332814,4.1997452686079e-05,DB0032110070863_,10.07790159,-0.381574092,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,amitriptyline,DB00321
,9302,DB01075,10070863,1134,18814,873,10224,1.53589780738591e-13,0.705929414,0.643594115,0.77445138,7.66782029765216e-12,DB0107510070863_,25.59398873,-0.348240026,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,9303,DB01104,10070863,557,14906,333,6953,0.000563841,0.780265226,0.677870459,0.899099495,0.003409375,DB0110410070863_,5.681226427,-0.248121384,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,9304,DB01222,10016256,591,8683,232,5173,7.98729956868613e-08,1.517610064,1.296323738,1.781153802,1.4750937572942e-06,DB0122210016256_,13.42678901,0.417136771,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,9305,DB00451,10016338,95,47176,12,15407,0.000694073,2.585557404,1.41278305,5.18078748,0.004062282,DB0045110016338_,5.506010441,0.949941115,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,9307,DB01222,10025482,327,8947,95,5310,2.17586692910769e-10,2.042778683,1.616440302,2.601653568,6.72854849783478e-09,DB0122210025482_,18.81690639,0.714310981,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,9308,DB00005,10024774,374,127708,157,42262,0.013718519,0.788323696,0.652346614,0.956315601,0.045801001,DB0000510024774_,3.083449326,-0.237846491,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,9309,DB00005,10031252,84,127998,55,42364,0.000162908,0.505465021,0.355525072,0.723803513,0.0012103,DB0000510031252_,6.716887002,-0.68227644,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,etanercept,DB00005
,9311,DB01238,10060933,61,5189,44,3458,0.689771909,0.923895339,0.615191445,1.397467283,0.812888491,DB0123810060933_,0.207161336,-0.079156483,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,9321,DB01267,10022086,82,2770,69,3646,0.007687745,1.564097251,1.117122576,2.195420198,0.028857793,DB0126710022086_,3.545375192,0.447308821,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,9322,DB00047,10037087,165,9120,97,8421,0.00046393,1.570610203,1.212667794,2.043522782,0.002901166,DB0004710037087_,5.842642613,0.451464208,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,insulin glargine,DB00047
,9323,DB00047,10037844,199,9086,144,8374,0.029034272,1.27363256,1.020453924,1.592746458,0.082557967,DB0004710037844_,2.494254602,0.241873101,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,insulin glargine,DB00047
,9326,DB00005,10022687,52,128030,21,42398,0.419631785,0.819990286,0.485375494,1.433379969,0.588568398,DB0000510022687_,0.530062135,-0.198462786,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,9328,DB00005,10005191,382,127700,90,42329,0.003308512,1.406888103,1.115218229,1.790879938,0.014642911,DB0000510005191_,4.223798944,0.341380246,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,9329,DB00005,10028372,523,127559,113,42306,1.85602331339012e-05,1.534973301,1.249984924,1.898841547,0.000187061,DB0000510028372_,8.584073332,0.428512987,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,9330,DB00005,10049816,99,127983,44,42375,0.120878333,0.74497353,0.517191517,1.088394223,0.24273555,DB0000510049816_,1.415782699,-0.294406591,NA,10049816,Muscle tightness,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,9332,DB01068,10012373,69,13694,24,6816,0.151113783,1.430968301,0.886899575,2.383784391,0.285418444,DB0106810012373_,1.253798951,0.358351349,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,9335,DB01224,10012373,81,8027,32,5885,0.002877377,1.855700878,1.216581621,2.892539556,0.01306608,DB0122410012373_,4.337735687,0.618262457,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,9336,DB01068,10033295,261,13502,133,6707,0.828998367,0.974789328,0.78641669,1.212959385,0.910163405,DB0106810033295_,0.09413113,-0.025533905,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,9337,DB01104,10033295,145,15318,61,7225,0.49978586,1.121166063,0.824657678,1.540171689,0.661507193,DB0110410033295_,0.413234422,0.114369271,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,9339,DB01224,10033295,191,7917,161,5756,0.172324304,0.862528693,0.693715439,1.073545238,0.313908614,DB0122410033295_,1.158653375,-0.147886863,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,9340,DB01068,10070863,876,12887,487,6353,0.042960803,0.886762144,0.789578483,0.996739778,0.111605526,DB0106810070863_,2.192784716,-0.12017849,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,9342,DB01224,10070863,1185,6923,746,5171,0.000673458,1.186462947,1.074097507,1.311104475,0.003967688,DB0122410070863_,5.529571675,0.170976568,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,9343,DB00005,10025197,300,127782,74,42345,0.022768667,1.343432425,1.03825975,1.75744225,0.068343453,DB0000510025197_,2.683209505,0.29522785,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,etanercept,DB00005
,9344,DB00005,10061598,56,128026,15,42404,0.582653825,1.236523788,0.689693953,2.354400061,0.730802176,DB0000510061598_,0.313612477,0.212304046,NA,10061598,Immunodeficiency,10021428,Immune system disorders,Immun,etanercept,DB00005
,9345,DB01267,10001488,31,2821,56,3659,0.157104622,0.718050283,0.446182787,1.136491646,0.29361636,DB0126710001488_,1.225481261,-0.33121568,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,9349,DB00331,10035598,112,24834,130,20622,0.009604678,0.715428002,0.550294692,0.928934011,0.034475388,DB0033110035598_,3.367509606,-0.334874311,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,9354,DB09053,10028411,48,2237,45,4007,0.00219045,1.910506294,1.240887304,2.945826548,0.010480082,DB0905310028411_,4.558278802,0.647368282,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ibrutinib,DB09053
,9355,DB09053,10035528,65,2220,125,3927,0.645474402,0.919840887,0.667738127,1.257210514,0.78117292,DB0905310035528_,0.246958745,-0.083554573,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,ibrutinib,DB09053
,9356,DB09053,10037844,62,2223,111,3941,1,0.990230466,0.71050158,1.369598708,1,DB0905310037844_,0,-0.009817569,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ibrutinib,DB09053
,9357,DB09053,10050584,103,2182,93,3959,2.25705196367762e-06,2.009299366,1.495515273,2.70251627,2.94790612995111e-05,DB0905310050584_,10.43183033,0.697786087,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,ibrutinib,DB09053
,9360,DB00482,10013968,194,8065,103,2968,0.003566588,0.693169156,0.540916521,0.892454021,0.015561087,DB0048210013968_,4.162981907,-0.366481217,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,celecoxib,DB00482
,9362,DB08865,10012735,105,1106,83,888,0.938943152,1.015702452,0.743752844,1.390624398,0.97859321,DB0886510012735_,0.021639238,0.015580444,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,crizotinib,DB08865
,9363,DB08865,10047571,65,1146,33,938,0.028939142,1.611850384,1.034386214,2.553886948,0.082336455,DB0886510047571_,2.496941321,0.477382826,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,crizotinib,DB08865
,9364,DB08865,10058467,34,1177,22,949,0.496411989,1.245955276,0.702513736,2.252458293,0.658588004,DB0886510058467_,0.417657123,0.219902526,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,crizotinib,DB08865
,9365,DB00186,10024264,114,16787,95,9913,0.014500116,0.7086517,0.534354277,0.941561733,0.047962695,DB0018610024264_,3.037331758,-0.344391128,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,9367,DB00563,10046735,364,46282,77,15271,0.000251297,1.55973134,1.215901025,2.022862159,0.001743522,DB0056310046735_,6.351848323,0.444513588,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,9368,DB01104,10013968,623,14840,245,7041,0.014349422,1.206451786,1.036129829,1.408295497,0.047542014,DB0110410013968_,3.046141463,0.187683643,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,9369,DB00316,10016288,277,65197,330,36623,4.2965743533784e-20,0.471506421,0.400254916,0.555126452,4.48156574914886e-18,DB0031610016288_,39.94655919,-0.751822558,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,9370,DB00433,10016288,188,7468,170,5850,0.195369784,0.8662954,0.698193566,1.075523398,0.343486489,DB0043310016288_,1.0686075,-0.143529321,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,prochlorperazine,DB00433
,9371,DB00497,10016288,131,19136,170,16205,0.000245625,0.652574885,0.515065895,0.82525661,0.001709131,DB0049710016288_,6.371770153,-0.426829379,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,oxycodone,DB00497
,9372,DB00526,10016288,30,1568,35,1859,1,1.016215542,0.599686313,1.712509972,1,DB0052610016288_,0,0.016085474,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,oxaliplatin,DB00526
,9373,DB00544,10016288,62,2373,88,2565,0.114936983,0.761592607,0.538497655,1.071591085,0.233525439,DB0054410016288_,1.454464263,-0.272343503,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,fluorouracil,DB00544
,9375,DB00650,10016288,55,2076,89,1925,0.00160523,0.573109842,0.399443726,0.816115692,0.008118032,DB0065010016288_,4.813667506,-0.556677885,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,leucovorin,DB00650
,9377,DB00762,10016288,40,1123,52,1317,0.670692712,0.90217318,0.577342948,1.400645334,0.800234132,DB0076210016288_,0.222850929,-0.102948782,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,irinotecan,DB00762
,9378,DB00904,10016288,323,22746,359,14097,5.68153157925958e-14,0.557639578,0.477579086,0.650852464,3.00783600323944e-12,DB0090410016288_,26.52980023,-0.584042443,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,ondansetron,DB00904
,9379,DB00316,10012174,846,64628,475,36478,0.9540165,1.005280025,0.896674125,1.128050574,0.991923566,DB0031610012174_,0.008109225,0.005266134,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,9380,DB01202,10012174,60,6654,55,5663,0.707744533,0.928453755,0.631965635,1.366328725,0.825353937,DB0120210012174_,0.191942971,-0.074234706,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,levetiracetam,DB01202
,9381,DB09037,10012174,35,2491,40,2795,1,0.981785895,0.603449254,1.590810242,1,DB0903710012174_,0,-0.018382024,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,pembrolizumab,DB09037
,9382,DB00182,10003549,93,5101,52,2800,0.930291881,0.981701241,0.689492066,1.410807602,0.971516672,DB0018210003549_,0.028896849,-0.018468252,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,9384,DB00490,10003549,96,3974,43,1533,0.443762993,0.861265008,0.591968297,1.270816549,0.61180196,DB0049010003549_,0.491346644,-0.149353031,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,9386,DB00182,10022437,130,5064,80,2772,0.421931276,0.889530939,0.665439909,1.195172747,0.590971337,DB0018210022437_,0.525987762,-0.11706099,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,9388,DB00490,10022437,109,3961,46,1530,0.649885429,0.915301538,0.63927884,1.328541345,0.784615544,DB0049010022437_,0.242561434,-0.088501719,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,buspirone,DB00490
,9390,DB00182,10041349,153,5041,86,2766,0.890839813,0.976164681,0.741503428,1.292011458,0.954680373,DB0018210041349_,0.046378682,-0.024123976,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,9391,DB00246,10041349,35,1039,25,676,0.788461191,0.910925376,0.524548819,1.60323461,0.885444006,DB0024610041349_,0.121666058,-0.0932943,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ziprasidone,DB00246
,9392,DB00490,10041349,94,3976,28,1548,0.26136234,1.306968868,0.845229589,2.079534091,0.42291506,DB0049010041349_,0.860583925,0.267710615,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,buspirone,DB00490
,9394,DB00182,10053762,150,5044,84,2768,0.889815499,0.979939647,0.742116511,1.301124231,0.954294357,DB0018210053762_,0.046783105,-0.020264294,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,amphetamine,DB00182
,9395,DB00246,10053762,44,1030,29,672,1,0.989893156,0.598902479,1.658123257,1,DB0024610053762_,0,-0.010158265,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ziprasidone,DB00246
,9396,DB00490,10053762,115,3955,43,1533,0.928348155,1.03665807,0.720378078,1.515677287,0.970147351,DB0049010053762_,0.030307311,0.036002145,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,buspirone,DB00490
,9397,DB06684,10053762,49,698,12,323,0.062796482,1.888583816,0.97349139,3.956389152,0.148663022,DB0668410053762_,1.90607313,0.635827244,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,vilazodone,DB06684
,9398,DB00404,10013754,125,19767,70,9792,0.44535468,0.884600278,0.654307108,1.204133456,0.613309841,DB0040410013754_,0.48888502,-0.1226194,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,9399,DB01068,10013754,136,13627,54,6786,0.16452154,1.254122865,0.907315367,1.754979918,0.303444924,DB0106810013754_,1.192555153,0.226436416,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,9410,DB01075,10019301,35,19913,15,11082,0.461567759,1.29855636,0.690686623,2.560441097,0.628812509,DB0107510019301_,0.463922145,0.261253155,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,diphenhydramine,DB01075
,9411,DB01234,10019301,59,31566,61,32827,1,1.005851588,0.690899354,1.463445567,1,DB0123410019301_,0,0.005834534,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,9412,DB00695,10007559,753,27296,652,19876,0.001474441,0.840970578,0.755005054,0.936896657,0.007582056,DB0069510007559_,4.881970888,-0.173198605,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,furosemide,DB00695
,9413,DB00761,10007559,323,14984,223,8402,0.019037439,0.812199813,0.681166017,0.969756499,0.059458065,DB0076110007559_,2.822484003,-0.208008893,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,9422,DB06643,10054112,150,52271,23,7492,0.73040362,0.934743524,0.59967573,1.520834624,0.84315587,DB0664310054112_,0.170603439,-0.067483094,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,denosumab,DB06643
,9426,DB00186,10011906,1004,15897,727,9281,2.19552596224337e-05,0.80628498,0.729607696,0.891330578,0.000216424,DB0018610011906_,8.438272146,-0.215318026,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,9428,DB00331,10011906,668,24278,898,19854,6.42473898530141e-22,0.608340293,0.548536293,0.674367705,8.11895501099267e-20,DB0033110011906_,43.95750041,-0.497020861,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,9429,DB00722,10011906,829,24574,1101,24931,8.33190275475655e-09,0.763896839,0.696007236,0.838168226,1.90687038666762e-07,DB0072210011906_,15.47263229,-0.269322526,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,9430,DB00983,10011906,41,3460,61,1679,2.97655678375247e-08,0.326234977,0.213108045,0.494927763,6.01605498353969e-07,DB0098310011906_,14.32366392,-1.12013737,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,formoterol,DB00983
,9431,DB01076,10011906,862,24885,1410,24173,5.38288850302708e-33,0.593866752,0.543953722,0.648074946,1.46620957825976e-30,DB0107610011906_,68.69487224,-0.521100309,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,9432,DB01409,10011906,273,5758,296,3670,9.52770033657475e-10,0.587902114,0.494247225,0.699059435,2.65996392296195e-08,DB0140910011906_,17.44236818,-0.531194818,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,9433,DB00046,10005554,85,5374,82,4610,0.48151511,0.88922933,0.647007328,1.222748368,0.64612526,DB0004610005554_,0.436761893,-0.117400113,NA,10005554,Blood glucose abnormal,10022891,Investigations,Inv,insulin lispro,DB00046
,9434,DB00046,10013709,315,5144,271,4421,1,0.998989344,0.842215529,1.185547053,1,DB0004610013709_,0,-0.001011167,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,9436,DB00203,10028735,510,13368,155,8783,1.55490208494219e-18,2.161719019,1.798683599,2.6098465,1.40207894691957e-16,DB0020310028735_,36.50340539,0.770903747,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,9437,DB00030,10011224,67,2139,53,1768,0.85256882,1.044887408,0.713629968,1.536450089,0.927844796,DB0003010011224_,0.074890805,0.043909136,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin human,DB00030
,9438,DB00177,10011224,130,4670,53,2797,0.020075051,1.469001502,1.055551459,2.06941689,0.061951597,DB0017710011224_,2.781401893,0.38458292,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,valsartan,DB00177
,9440,DB00207,10011224,264,8816,172,5283,0.42175032,0.919787672,0.753801464,1.124628394,0.590828075,DB0020710011224_,0.526230209,-0.083612427,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,9442,DB00331,10011224,454,24492,265,20487,3.26292391873584e-06,1.433044869,1.22739594,1.675810095,4.07439217121005e-05,DB0033110011224_,10.10820389,0.35980146,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,9443,DB00381,10011224,683,28677,298,22589,3.54572187981186e-18,1.805341368,1.571564551,2.077808691,3.10147419670065e-16,DB0038110011224_,35.70948394,0.590749698,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,9444,DB00451,10011224,1000,46271,273,15146,0.008499184,1.199011313,1.046395681,1.377552637,0.031262393,DB0045110011224_,3.465339394,0.181497312,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,9445,DB00582,10011224,30,1100,32,1542,0.299399855,1.314054098,0.766382712,2.247668723,0.465416357,DB0058210011224_,0.764822882,0.27311709,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,voriconazole,DB00582
,9446,DB00588,10011224,593,15931,282,8186,0.308708986,1.080527425,0.933674125,1.252739645,0.476034641,DB0058810011224_,0.742264653,0.077449278,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,9448,DB00641,10011224,309,13815,182,12293,1.10972525938746e-05,1.510727031,1.251742265,1.82753889,0.000118718,DB0064110011224_,9.038755654,0.412591013,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,9449,DB01137,10011224,182,7590,132,5461,0.953885246,0.992036518,0.786311083,1.254261774,0.991806713,DB0113710011224_,0.008227037,-0.00799536,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,9451,DB01409,10011224,268,5763,112,3854,2.88498733237801e-05,1.600146633,1.273695741,2.021161566,0.000274157,DB0140910011224_,8.201808755,0.470095271,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,9453,DB00030,10013709,111,2095,113,1708,0.11223353,0.800893495,0.605772465,1.058643592,0.229406923,DB0003010013709_,1.472257895,-0.222027306,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,insulin human,DB00030
,9454,DB00177,10013709,283,4517,167,2683,0.959970907,1.006561275,0.823292642,1.233605949,0.997601569,DB0017710013709_,0.002401312,0.006539843,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,9455,DB00204,10013709,83,881,73,970,0.18282581,1.251701293,0.890407051,1.762684659,0.327460248,DB0020410013709_,1.116388612,0.22450366,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dofetilide,DB00204
,9456,DB00207,10013709,326,8754,204,5251,0.647854564,0.95859457,0.79946851,1.151452065,0.782917966,DB0020710013709_,0.244727358,-0.042287057,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,9458,DB00331,10013709,1093,23853,913,19839,0.92693333,0.995694467,0.909241728,1.090563009,0.969118049,DB0033110013709_,0.031368849,-0.004314829,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,9459,DB00582,10013709,68,1062,123,1451,0.07996618,0.755424789,0.547337673,1.035653919,0.178362809,DB0058210013709_,1.723935551,-0.280475053,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,voriconazole,DB00582
,9460,DB00624,10013709,47,515,306,4090,0.22280446,1.21974097,0.86558802,1.687881426,0.376957726,DB0062410013709_,0.975622231,0.198638516,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,testosterone,DB00624
,9461,DB00641,10013709,614,13510,481,11994,0.044473877,1.133260574,1.001533344,1.282899003,0.114545671,DB0064110013709_,2.166781658,0.125098941,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,9462,DB00682,10013709,396,19063,447,15917,1.63660993679427e-05,0.739715562,0.643413743,0.850153093,0.000167224,DB0068210013709_,8.696178229,-0.301489542,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,9463,DB01137,10013709,220,7552,177,5416,0.2781437,0.891395802,0.725677143,1.096191384,0.441926264,DB0113710013709_,0.816612234,-0.114966728,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,9466,DB00177,10013968,243,4557,122,2728,0.134088929,1.192309021,0.950195062,1.502338088,0.261453767,DB0017710013968_,1.341497812,0.175891781,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,valsartan,DB00177
,9467,DB00204,10013968,77,887,52,991,0.006295039,1.653955542,1.134198935,2.427861514,0.024608134,DB0020410013968_,3.704678249,0.503169717,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dofetilide,DB00204
,9468,DB00207,10013968,367,8713,238,5217,0.345839635,0.923304865,0.779277648,1.095512911,0.515296661,DB0020710013968_,0.663012504,-0.079795801,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,9470,DB00582,10013968,43,1087,43,1531,0.120978721,1.408257394,0.894163864,2.218075211,0.242856904,DB0058210013968_,1.41528288,0.342353049,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,voriconazole,DB00582
,9471,DB00624,10013968,15,547,114,4282,0.888072495,1.030018697,0.554089515,1.787549447,0.953631242,DB0062410013968_,0.047478221,0.029576954,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,testosterone,DB00624
,9472,DB00682,10013968,2448,17011,1092,15272,6.03168607416526e-80,2.012538302,1.867059146,2.170434169,8.34436149786494e-77,DB0068210013968_,175.1774661,0.699396762,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,9473,DB01137,10013968,314,7458,235,5358,0.65874338,0.959913759,0.804999456,1.145907349,0.791600722,DB0113710013968_,0.233698153,-0.040911833,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,9475,DB01409,10013968,818,5213,475,3491,0.020635782,1.15321478,1.020339788,1.304418833,0.063354098,DB0140910013968_,2.75901568,0.142553504,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,9477,DB00338,10011224,821,32853,432,21840,9.07991387186563e-05,1.26338311,1.121648136,1.424598642,0.000734808,DB0033810011224_,7.215901746,0.233793131,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,9478,DB01222,10011224,351,8923,206,5199,0.928703929,0.992769605,0.830550377,1.189046764,0.970364828,DB0122210011224_,0.030083167,-0.007256661,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,9481,DB13867,10011224,130,4420,62,2492,0.321607236,1.182171106,0.863307914,1.633353875,0.489906036,DB1386710011224_,0.71354167,0.167352668,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,9489,DB13867,10053762,103,4447,49,2505,0.348683599,1.184088974,0.831571241,1.705840675,0.518170934,DB1386710053762_,0.657450103,0.16897368,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone,DB13867
,9491,DB06403,10016807,1068,20403,360,6301,0.169471873,0.916180874,0.809462662,1.03877266,0.310195897,DB0640310016807_,1.170551256,-0.087541473,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,ambrisentan,DB06403
,9493,DB06228,10011224,254,15658,145,15931,2.45937382471845e-08,1.782221772,1.445804511,2.203655483,5.05826611758408e-07,DB0622810011224_,14.49707189,0.577860773,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,9494,DB06228,10018964,158,15754,249,15827,1.05131477222878e-05,0.637491039,0.518270209,0.78224429,0.000113369,DB0622810018964_,9.08485841,-0.450215058,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,9495,DB00921,10000087,38,5807,39,4864,0.421845918,0.816151047,0.507232402,1.312170314,0.590908918,DB0092110000087_,0.526093389,-0.203155834,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,buprenorphine,DB00921
,9496,DB00921,10012735,112,5733,80,4823,0.273778857,1.177759355,0.873750185,1.593675634,0.436839607,DB0092110012735_,0.828189183,0.163613782,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,buprenorphine,DB00921
,9497,DB00921,10019211,326,5519,199,4704,0.000269222,1.396230357,1.161758649,1.681284098,0.001846688,DB0092110019211_,6.294361783,0.333776003,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,buprenorphine,DB00921
,9498,DB00921,10020642,151,5694,147,4756,0.194942151,0.8580075,0.676836975,1.087892002,0.342925892,DB0092110020642_,1.070240913,-0.153142439,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,buprenorphine,DB00921
,9499,DB00921,10037844,153,5692,92,4811,0.011276339,1.405593137,1.075024076,1.84612027,0.039167304,DB0092110037844_,3.239912968,0.340459375,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,buprenorphine,DB00921
,9500,DB08899,10011906,7,242,1741,6392,3.69252844748223e-17,0.106213183,0.042184151,0.222798677,2.90158775013663e-15,DB0889910011906_,33.47351831,-2.242307045,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,enzalutamide,DB08899
,9501,DB00005,10016173,1665,126417,361,42058,2.0667690730229e-14,1.534389115,1.367817017,1.725160755,1.16327676840272e-12,DB0000510016173_,27.47978029,0.428132331,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,9502,DB00005,10022116,110,127972,40,42379,0.63658784,0.910675684,0.628739244,1.34290806,0.774089164,DB0000510022116_,0.256068212,-0.093568445,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,9507,DB00213,10002855,306,18589,118,13303,5.16275096989401e-09,1.855765251,1.493999069,2.31763838,1.23534737590955e-07,DB0021310002855_,15.90674344,0.618297145,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,9508,DB00722,10002855,370,25033,193,25839,5.12217954514993e-15,1.978785167,1.656749833,2.369378256,3.14204175832593e-13,DB0072210002855_,28.78873338,0.682483104,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,9509,DB00921,10002855,128,5717,112,4791,0.743644071,0.957729323,0.735109736,1.249269765,0.853436566,DB0092110002855_,0.158484061,-0.043190084,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,9510,DB01224,10002855,216,7892,124,5793,0.03451422,1.278617849,1.017755137,1.612086832,0.094441627,DB0122410002855_,2.359773337,0.245779689,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,9511,DB01306,10002855,50,4158,26,3840,0.020472837,1.775871944,1.082146062,2.97860546,0.062939009,DB0130610002855_,2.765589128,0.574291538,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,insulin aspart,DB01306
,9513,DB00213,10012378,296,18599,123,13298,2.43305898306058e-07,1.720580397,1.387968634,2.143487695,4.05021883278957e-06,DB0021310012378_,12.41673965,0.542661674,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,9514,DB00472,10012378,366,10393,133,4179,0.338843977,1.106514484,0.901794764,1.364281071,0.507927797,DB0047210012378_,0.677415973,0.10121497,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,9515,DB00722,10012378,390,25013,233,25799,2.9845941265585e-11,1.726386452,1.462596677,2.041311536,1.05870521749784e-09,DB0072210012378_,20.66621917,0.546030468,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,9516,DB00921,10012378,69,5776,54,4849,0.716730589,1.072720388,0.738784202,1.564521087,0.83251017,DB0092110012378_,0.183309841,0.07019784,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,9517,DB01224,10012378,198,7910,137,5780,0.654391528,1.056083669,0.842748341,1.326473961,0.788208561,DB0122410012378_,0.237992553,0.054567415,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,9518,DB01306,10012378,61,4147,32,3834,0.009000893,1.762245912,1.127998177,2.800615695,0.03271864,DB0130610012378_,3.41981034,0.566589082,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,insulin aspart,DB01306
,9519,DB01373,10012378,342,22378,73,7308,0.000833701,1.529897038,1.183411405,2.000783224,0.004739045,DB0137310012378_,5.351919688,0.425200437,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,calcium,DB01373
,9521,DB00213,10024264,80,18815,71,13350,0.185389565,0.799494018,0.573002335,1.117397133,0.330695538,DB0021310024264_,1.106557152,-0.223776229,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,9522,DB00472,10024264,66,10693,37,4275,0.101664275,0.713163673,0.46903476,1.099151799,0.213404046,DB0047210024264_,1.544567981,-0.338044329,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,9523,DB00476,10024264,713,16544,262,5915,0.710510114,0.97297684,0.840597503,1.128839219,0.827349415,DB0047610024264_,0.189528164,-0.027395,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,9524,DB00722,10024264,108,25295,113,25919,0.892905281,0.979326972,0.744825764,1.287096519,0.955415161,DB0072210024264_,0.045609309,-0.020889707,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,9525,DB00921,10024264,23,5822,38,4865,0.009718085,0.505810123,0.287266006,0.872439459,0.034790395,DB0092110024264_,3.358413929,-0.681593931,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,buprenorphine,DB00921
,9527,DB01373,10024264,64,22656,43,7338,0.00040949,0.482063823,0.322183637,0.727609049,0.002613756,DB0137310024264_,5.946966963,-0.729678762,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,calcium,DB01373
,9529,DB00213,10027175,195,18700,63,13358,1.16839202908318e-08,2.210958293,1.6547011,2.988905729,2.5872943963312e-07,DB0021310027175_,15.16748296,0.793426038,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,9530,DB00472,10027175,117,10642,44,4268,0.792631766,1.066429871,0.746553439,1.547514844,0.88758728,DB0047210027175_,0.119248419,0.064316501,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,9531,DB00476,10027175,364,16893,98,6079,0.010457647,1.336555371,1.06439146,1.691479824,0.036874273,DB0047610027175_,3.300241193,0.290095686,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,9532,DB00722,10027175,272,25131,176,25856,1.50413181787058e-06,1.590014097,1.309452795,1.934670385,2.06454855523385e-05,DB0072210027175_,10.78801388,0.463742882,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,9533,DB00921,10027175,30,5815,24,4879,0.891900518,1.048802069,0.591878132,1.877258354,0.955030252,DB0092110027175_,0.046012261,0.047648626,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,buprenorphine,DB00921
,9534,DB01306,10027175,33,4175,26,3840,0.602144678,1.167365241,0.675736798,2.036530721,0.746241313,DB0130610027175_,0.292706255,0.154749279,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,insulin aspart,DB01306
,9535,DB01373,10027175,276,22444,72,7309,0.103058859,1.248327095,0.958526843,1.643677882,0.215582517,DB0137310027175_,1.534411533,0.221804331,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,calcium,DB01373
,9536,DB00030,10033371,73,2133,35,1786,0.007878148,1.746170245,1.145572789,2.706565328,0.029416451,DB0003010033371_,3.526201193,0.557424959,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,insulin human,DB00030
,9537,DB00213,10033371,715,18180,279,13142,4.85138048626778e-19,1.852502988,1.607851965,2.138928886,4.58699770077513e-17,DB0021310033371_,37.62072087,0.616537691,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,9538,DB00472,10033371,375,10384,90,4222,4.14196715111076e-06,1.69405993,1.338543373,2.162951803,5.00519960917508e-05,DB0047210033371_,9.902448171,0.527127973,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,9539,DB00476,10033371,1019,16238,237,5940,1.87566037022467e-10,1.572821608,1.359746681,1.825106021,5.8692539084947e-09,DB0047610033371_,18.95353831,0.452871209,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,9540,DB00722,10033371,958,24445,542,25490,3.10938755476751e-30,1.843051142,1.654565231,2.054663277,7.0762122837285e-28,DB0072210033371_,62.51564383,0.611422428,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,9541,DB00921,10033371,228,5617,133,4770,0.000691506,1.455731056,1.166078079,1.823218163,0.004050414,DB0092110033371_,5.508936201,0.375508218,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,9542,DB01224,10033371,205,7903,79,5838,5.39847213569488e-07,1.916800229,1.468203955,2.523092589,8.31276157508729e-06,DB0122410033371_,11.69771868,0.650657248,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,9543,DB01238,10033371,132,5118,50,3452,0.000416069,1.780518731,1.272709403,2.525191637,0.002647069,DB0123810033371_,5.934302191,0.576904744,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,9544,DB01373,10033371,898,21822,174,7207,2.44031918756773e-11,1.704508597,1.444121412,2.02095392,8.75683137818674e-10,DB0137310033371_,20.85601681,0.533276857,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,9545,DB00030,10047899,44,2162,30,1791,0.479727547,1.214927138,0.743271585,2.010459928,0.64460146,DB0003010047899_,0.439123044,0.194684107,NA,10047899,Weight increased,10022891,Investigations,Inv,insulin human,DB00030
,9546,DB00213,10047899,300,18595,128,13293,7.05831837373027e-07,1.675445372,1.356096181,2.079681374,1.05293926477582e-05,DB0021310047899_,11.46133991,0.516079024,NA,10047899,Weight increased,10022891,Investigations,Inv,pantoprazole,DB00213
,9547,DB00472,10047899,184,10575,68,4244,0.62274721,1.085928228,0.81596346,1.459620642,0.762923745,DB0047210047899_,0.270597194,0.082435131,NA,10047899,Weight increased,10022891,Investigations,Inv,fluoxetine,DB00472
,9548,DB00476,10047899,385,16872,80,6097,2.68311653726783e-06,1.739100034,1.3610323,2.245392838,3.43190842735207e-05,DB0047610047899_,10.27980897,0.553367758,NA,10047899,Weight increased,10022891,Investigations,Inv,duloxetine,DB00476
,9549,DB00921,10047899,48,5797,13,4890,9.07674001532096e-05,3.114187762,1.658448983,6.273434273,0.000734664,DB0092110047899_,7.216097401,1.135968368,female,10047899,Weight increased,10022891,Investigations,Inv,buprenorphine,DB00921
,9550,DB01306,10047899,83,4125,44,3822,0.002997026,1.747676511,1.195031854,2.586536777,0.013499585,DB0130610047899_,4.305096328,0.558287198,NA,10047899,Weight increased,10022891,Investigations,Inv,insulin aspart,DB01306
,9554,DB00333,10038678,18,3053,36,3116,0.019860983,0.510373591,0.272212218,0.924951361,0.061409945,DB0033310038678_,2.790183486,-0.67261229,NA,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methadone,DB00333
,9555,DB00497,10038678,79,19188,91,16284,0.05352425,0.736756515,0.537634654,1.007794455,0.131613725,DB0049710038678_,2.027883973,-0.305497815,NA,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,9557,DB00497,10039897,49,19218,65,16310,0.018579949,0.63979215,0.432086746,0.942010276,0.058302867,DB0049710039897_,2.842104016,-0.446611922,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,9559,DB00497,10061422,33,19234,33,16342,0.537860233,0.84964691,0.508032992,1.420995026,0.693940814,DB0049710061422_,0.365368604,-0.162934416,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,9567,DB00921,10013756,29,5816,48,4855,0.003848618,0.50437595,0.306191659,0.817681539,0.016534965,DB0092110013756_,4.102278023,-0.684433357,NA,10013756,Drug withdrawal syndrome neonatal,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,9573,DB00921,10071404,48,5797,63,4840,0.02117159,0.636160255,0.426802395,0.942938601,0.064682424,DB0092110071404_,2.738265762,-0.452304773,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,buprenorphine,DB00921
,9574,DB00367,10053762,308,22492,10,457,0.153512326,0.625827416,0.332671068,1.327149746,0.28887324,DB0036710053762_,1.241767302,-0.468680639,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,levonorgestrel,DB00367
,9576,DB00367,10003239,71,22729,6,461,0.004517691,0.240039533,0.104241109,0.67944891,0.01882789,DB0036710003239_,3.972415975,-1.42695165,male,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,levonorgestrel,DB00367
,9580,DB00210,10020751,47,838,13,336,0.303549136,1.449232416,0.75931972,2.958818714,0.47008714,DB0021010020751_,0.754837197,0.371034048,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,adapalene,DB00210
,9586,DB09072,10039203,47,6424,22,2513,0.502352195,0.835763416,0.49255281,1.459476513,0.663630379,DB0907210039203_,0.410029943,-0.179409701,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium oxybate,DB09072
,9587,DB09072,10050296,37,6434,33,2502,0.00073407,0.436048452,0.264638848,0.721264801,0.004254694,DB0907210050296_,5.459732324,-0.830001913,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium oxybate,DB09072
,9592,DB01590,10003549,126,4612,122,2745,0.000183445,0.614768459,0.473191232,0.798844961,0.001340891,DB0159010003549_,6.614420851,-0.486509572,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,9593,DB01590,10061428,186,4552,158,2709,0.001418851,0.700644538,0.560568663,0.876486779,0.007339272,DB0159010061428_,4.914515626,-0.355754599,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,everolimus,DB01590
,9594,DB00060,10022052,164,9344,26,2439,0.018308588,1.64636728,1.081052891,2.601869636,0.05761643,DB0006010022052_,2.853947504,0.498571212,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,9595,DB00060,10028813,253,9255,36,2429,0.00038153,1.844332352,1.293004513,2.7010417,0.002465223,DB0006010028813_,6.005472861,0.612117343,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,interferon beta-1a,DB00060
,9599,DB00285,10013710,199,10752,89,3629,0.033687958,0.754691963,0.583151551,0.983094297,0.092750389,DB0028510013710_,2.377843384,-0.281445609,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,9600,DB00370,10013710,75,4466,71,3592,0.355728016,0.84963098,0.603986569,1.196174621,0.525445828,DB0037010013710_,0.64350818,-0.162953165,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,9607,DB00285,10024855,95,10856,32,3686,1,1.007997259,0.667584864,1.558411279,1,DB0028510024855_,0,0.007965451,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,9613,DB00285,10070863,604,10347,285,3433,3.76030741321771e-06,0.703173896,0.606455532,0.816725763,4.59826379885682e-05,DB0028510070863_,9.987246668,-0.352151055,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,9614,DB00370,10070863,241,4300,166,3497,0.112944969,1.180666311,0.959823393,1.455061674,0.230513038,DB0037010070863_,1.467447855,0.166078949,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,mirtazapine,DB00370
,9615,DB00295,10020642,97,14566,102,9500,0.001004489,0.620265301,0.464246929,0.828225246,0.005524794,DB0029510020642_,5.198509296,-0.477607987,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,morphine,DB00295
,9616,DB01012,10013573,126,10506,98,8587,0.735891632,1.050876942,0.799324789,1.384872469,0.847406972,DB0101210013573_,0.165574213,0.049624998,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,cinacalcet,DB01012
,9617,DB01012,10028813,570,10062,361,8324,0.000101485,1.306197352,1.139074623,1.499309081,0.000807856,DB0101210028813_,7.121126471,0.267120131,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cinacalcet,DB01012
,9618,DB00005,10028735,745,127337,183,42236,0.000217426,1.350288979,1.146741345,1.596737461,0.001546072,DB0000510028735_,6.472037751,0.300318628,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,9619,DB00005,10052137,87,127995,20,42399,0.147122363,1.440928611,0.878431631,2.474533133,0.279951593,DB0000510052137_,1.273138574,0.365287775,NA,10052137,Ear discomfort,10013993,Ear and labyrinth disorders,Ear,etanercept,DB00005
,9620,DB00005,10070488,129,127953,20,42399,0.000835112,2.137150665,1.328005865,3.615926371,0.004744603,DB0000510070488_,5.350747436,0.759473477,NA,10070488,Upper-airway cough syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,9622,DB00115,10005724,104,18321,32,10440,0.001690559,1.851935771,1.234537545,2.847572622,0.008467289,DB0011510005724_,4.771544861,0.616231455,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,9623,DB00316,10005724,274,65200,98,36855,7.4623817503848e-05,1.580415675,1.249964801,2.012187346,0.000620135,DB0031610005724_,7.385573342,0.457687898,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,9624,DB00338,10005724,174,33500,68,22204,0.000165871,1.695985475,1.273661116,2.280356897,0.001230443,DB0033810005724_,6.700381377,0.528263973,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,omeprazole,DB00338
,9625,DB00343,10005724,59,8677,21,5074,0.048851035,1.642853762,0.982189966,2.85022001,0.122828529,DB0034310005724_,2.096965969,0.496434828,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,diltiazem,DB00343
,9627,DB00433,10005724,49,7607,27,5993,0.164024831,1.429721612,0.875089958,2.382026013,0.302798236,DB0043310005724_,1.194688582,0.357479748,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,prochlorperazine,DB00433
,9628,DB00588,10005724,87,16437,22,8446,0.002202626,2.031955143,1.260081171,3.410267578,0.010523679,DB0058810005724_,4.554127451,0.708998454,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,9630,DB00678,10005724,72,15527,29,10695,0.014609735,1.710087784,1.09616733,2.732385244,0.048282134,DB0067810005724_,3.030693682,0.536544705,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,losartan,DB00678
,9631,DB00996,10005724,166,38787,55,22370,0.000258171,1.740689279,1.275388772,2.40745122,0.001784856,DB0099610005724_,6.32841734,0.554281172,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,gabapentin,DB00996
,9632,DB01076,10005724,121,25626,65,25518,4.80815198205018e-05,1.8536602,1.359507516,2.547249717,0.000427328,DB0107610005724_,7.757958541,0.617162171,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,9633,DB01234,10005724,249,31376,111,32777,1.19595164472299e-14,2.343387347,1.865212487,2.959710105,6.9547763233504e-13,DB0123410005724_,27.99417754,0.851597467,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,9636,DB00091,10016256,283,5227,73,2597,3.1058327251097e-07,1.925980747,1.477285199,2.537872217,5.04242206173617e-06,DB0009110016256_,12.19762402,0.655435317,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,9637,DB00364,10016256,206,2544,95,1305,0.447560021,1.112326003,0.859739478,1.447235225,0.61531017,DB0036410016256_,0.485628796,0.106453321,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sucralfate,DB00364
,9638,DB00433,10016256,761,6895,541,5479,0.060385954,1.117746734,0.994065265,1.257471838,0.144144285,DB0043310016256_,1.936940499,0.111314814,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,9639,DB00654,10016256,178,3638,121,2477,1,1.001608125,0.785949025,1.279875007,1,DB0065410016256_,0,0.001606833,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,9640,DB00678,10016256,1065,14534,674,10050,0.085944789,1.092644267,0.987850044,1.209114774,0.188262742,DB0067810016256_,1.669916726,0.088600691,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,9641,DB08889,10016256,287,2878,328,3557,0.37294421,1.081424235,0.912707761,1.280847797,0.542627581,DB0888910016256_,0.611332049,0.078278908,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,9642,DB11093,10016256,136,1521,54,606,1,1.00343194,0.716008009,1.422252173,1,DB1109310016256_,0,0.003426065,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,calcium citrate,DB11093
,9644,DB00115,10020919,52,18373,27,10445,0.814814145,1.09489111,0.674734251,1.814342181,0.900608932,DB0011510020919_,0.104684153,0.090654915,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,cyanocobalamin,DB00115
,9645,DB00316,10020919,209,65265,107,36846,0.445745557,1.10274966,0.869106784,1.405944292,0.613581754,DB0031610020919_,0.488441765,0.097806752,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,9646,DB00338,10020919,152,33522,87,22185,0.290099264,1.156211872,0.882165764,1.523558485,0.455303111,DB0033810020919_,0.786791904,0.145149033,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,9647,DB00343,10020919,87,8649,40,5055,0.230048423,1.2711965,0.863088025,1.900892596,0.386013243,DB0034310020919_,0.951883601,0.239958583,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,diltiazem,DB00343
,9650,DB00588,10020919,87,16437,36,8432,0.29494387,1.239675253,0.830882634,1.884245016,0.460862239,DB0058810020919_,0.774656112,0.214849452,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,fluticasone propionate,DB00588
,9652,DB00678,10020919,54,15545,27,10697,0.212578647,1.376245417,0.85129762,2.274116659,0.364526044,DB0067810020919_,1.009157278,0.319359079,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,9653,DB00996,10020919,118,38835,58,22367,0.34737181,1.171786763,0.848317699,1.634197088,0.516835141,DB0099610020919_,0.660031332,0.158529732,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,9654,DB01076,10020919,139,25608,109,25474,0.065021885,1.268547578,0.979451866,1.646432156,0.152482512,DB0107610020919_,1.880705365,0.237872606,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,9655,DB01234,10020919,54,31571,54,32834,0.847868396,1.040016956,0.699595711,1.545992031,0.923934364,DB0123410020919_,0.079114244,0.039237017,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,9659,DB00115,10017885,161,18264,52,10420,0.000249005,1.766388443,1.283445087,2.465982586,0.001729218,DB0011510017885_,6.360085715,0.568937034,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,9660,DB00316,10017885,371,65103,147,36806,0.000236214,1.42683152,1.17509952,1.739921991,0.001655338,DB0031610017885_,6.403750054,0.355456265,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,9661,DB00338,10017885,410,33264,190,22082,3.82846630014811e-05,1.432488985,1.202139112,1.711979912,0.00035155,DB0033810017885_,7.95315812,0.35941348,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,9662,DB00343,10017885,62,8674,21,5074,0.029967326,1.726980251,1.036698727,2.98692449,0.084643366,DB0034310017885_,2.469308538,0.546374364,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,9663,DB00364,10017885,49,2701,18,1382,0.244304222,1.39275364,0.793384503,2.550596358,0.402884852,DB0036410017885_,0.909104485,0.331282823,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,sucralfate,DB00364
,9665,DB00588,10017885,162,16362,47,8421,0.000401346,1.773925267,1.273433604,2.512682305,0.0025702,DB0058810017885_,5.963771657,0.573194756,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,9667,DB00678,10017885,121,15478,50,10674,0.002235794,1.668855928,1.189795239,2.371345671,0.010652137,DB0067810017885_,4.541994767,0.512138319,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,9668,DB00996,10017885,198,38755,81,22344,0.008823658,1.409324415,1.0823566,1.849354583,0.03220577,DB0099610017885_,3.435609646,0.343110451,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,9669,DB01076,10017885,160,25587,106,25477,0.001100323,1.502925116,1.167722975,1.940897592,0.005957154,DB0107610017885_,5.123162485,0.407413287,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,9670,DB01234,10017885,131,31494,81,32807,0.000193812,1.684683381,1.266802626,2.25188542,0.001403206,DB0123410017885_,6.568995786,0.521577642,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,9673,DB00091,10021097,55,5455,20,2650,0.32233849,1.335921566,0.786072644,2.358364278,0.490674598,DB0009110021097_,0.711974104,0.289621366,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,cyclosporine,DB00091
,9674,DB00338,10021097,486,33188,398,21874,0.001611455,0.804833957,0.702682573,0.922216741,0.008145594,DB0033810021097_,4.81027817,-0.217119288,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,omeprazole,DB00338
,9675,DB00364,10021097,56,2694,38,1362,0.185232775,0.745131847,0.48209748,1.162570808,0.3304944,DB0036410021097_,1.107165564,-0.2941941,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sucralfate,DB00364
,9676,DB00433,10021097,123,7533,143,5877,0.001430515,0.671082689,0.521691565,0.862181162,0.00739233,DB0043310021097_,4.907312328,-0.398862918,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,prochlorperazine,DB00433
,9677,DB00588,10021097,234,16290,127,8341,0.614317057,0.943431809,0.755612783,1.18231737,0.755840897,DB0058810021097_,0.279924379,-0.058231191,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,fluticasone propionate,DB00588
,9678,DB00654,10021097,39,3777,43,2555,0.031131859,0.613601525,0.38616314,0.972226569,0.087201717,DB0065410021097_,2.439531252,-0.488409543,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,latanoprost,DB00654
,9679,DB00996,10021097,502,38451,384,22041,2.82504675306251e-05,0.749393168,0.654128333,0.859018992,0.000269289,DB0099610021097_,8.219726589,-0.288491509,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,gabapentin,DB00996
,9680,DB01076,10021097,395,25352,548,25035,3.29979398422239e-07,0.711798153,0.623074874,0.812577056,5.32280361308902e-06,DB0107610021097_,12.1435104,-0.3399609,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,atorvastatin,DB01076
,9681,DB01234,10021097,460,31165,590,32298,0.000687519,0.808009567,0.712977823,0.915257651,0.0040329,DB0123410021097_,5.513269556,-0.21318138,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,dexamethasone,DB01234
,9682,DB08889,10021097,21,3144,34,3851,0.342967731,0.756569416,0.416362458,1.34474586,0.512297937,DB0888910021097_,0.668848915,-0.278960991,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,carfilzomib,DB08889
,9684,DB00115,10047513,189,18236,78,10394,0.017797167,1.381069893,1.054197621,1.823853034,0.056381478,DB0011510047513_,2.875614586,0.322858483,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,cyanocobalamin,DB00115
,9685,DB00316,10047513,478,64996,180,36773,2.17389545821406e-06,1.502436345,1.262530776,1.794294648,2.85276296151555e-05,DB0031610047513_,10.46463748,0.407088021,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,acetaminophen,DB00316
,9686,DB00338,10047513,273,33401,134,22138,0.004390028,1.35031247,1.093359027,1.674316622,0.018412695,DB0033810047513_,3.994714908,0.300336025,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,omeprazole,DB00338
,9687,DB00343,10047513,72,8664,32,5063,0.221137204,1.314812166,0.854326711,2.064282741,0.374921237,DB0034310047513_,0.981039308,0.273693816,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,diltiazem,DB00343
,9689,DB00433,10047513,35,7621,33,5987,0.464711107,0.833218308,0.502253096,1.38513239,0.631718105,DB0043310047513_,0.459312021,-0.182459596,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,prochlorperazine,DB00433
,9690,DB00588,10047513,131,16393,61,8407,0.592218595,1.101338661,0.805805213,1.51973943,0.738465935,DB0058810047513_,0.303180305,0.096526404,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,fluticasone propionate,DB00588
,9691,DB00654,10047513,90,3726,54,2544,0.492711772,1.137966228,0.799936498,1.631891036,0.655556268,DB0065410047513_,0.422271139,0.129242659,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,latanoprost,DB00654
,9692,DB00678,10047513,162,15437,70,10654,0.000972219,1.597197917,1.198142641,2.147832724,0.005383918,DB0067810047513_,5.224338832,0.468250792,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,losartan,DB00678
,9693,DB01076,10047513,194,25553,147,25436,0.014366782,1.313674281,1.054015968,1.640169406,0.047584534,DB0107610047513_,3.04524749,0.272828006,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,atorvastatin,DB01076
,9694,DB01234,10047513,243,31382,171,32717,7.74489089277441e-05,1.48148648,1.212432843,1.813500497,0.000640272,DB0123410047513_,7.353617596,0.393045962,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,dexamethasone,DB01234
,9697,DB00005,10039117,89,127993,37,42382,0.256685344,0.796492463,0.537062321,1.202688603,0.417531889,DB0000510039117_,0.873394356,-0.227537612,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,9698,DB00005,10041569,97,127985,33,42386,0.919168039,0.973465682,0.649638543,1.492496035,0.964291834,DB0000510041569_,0.036361298,-0.026892707,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,9701,DB00005,10005483,53,128029,26,42393,0.117151595,0.674977974,0.414597161,1.124626533,0.236864288,DB0000510005483_,1.440267924,-0.39307522,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,etanercept,DB00005
,9702,DB00005,10013911,170,127912,61,42358,0.594167326,0.922867915,0.684833636,1.258000473,0.740157255,DB0000510013911_,0.300892608,-0.080269159,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,9703,DB00005,10038428,135,127947,54,42365,0.239185798,0.827762948,0.599398591,1.157303911,0.396919012,DB0000510038428_,0.924023019,-0.18902846,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,etanercept,DB00005
,9704,DB00982,10012378,288,3076,271,1830,4.12722217799484e-07,0.632330116,0.52836414,0.756843567,6.50969306622229e-06,DB0098210012378_,11.94221825,-0.458343685,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,isotretinoin,DB00982
,9709,DB01202,10018100,132,6582,99,5619,0.351273091,1.138237967,0.86824338,1.49620186,0.521002888,DB0120210018100_,0.651999693,0.129481423,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,9710,DB06218,10018100,65,1629,60,1376,0.647662121,0.915107301,0.629351095,1.332437204,0.78282977,DB0621810018100_,0.244840014,-0.088713951,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,lacosamide,DB06218
,9711,DB00924,10022523,74,10088,21,4230,0.141539027,1.477575325,0.898530668,2.52994066,0.271965593,DB0092410022523_,1.302079717,0.39040245,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,9712,DB01202,10022523,28,6686,30,5688,0.428804954,0.794035612,0.456509697,1.377131129,0.597336278,DB0120210022523_,0.515275045,-0.230626968,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,levetiracetam,DB01202
,9714,DB00924,10042464,70,10092,10,4241,0.000493255,2.941303347,1.506525975,6.407323742,0.003058684,DB0092410042464_,5.789770572,1.078852798,female,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,9715,DB01202,10042464,18,6696,40,5678,0.000504205,0.381613505,0.205682704,0.682075783,0.003111331,DB0120210042464_,5.772704737,-0.96334695,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,9717,DB00924,10045555,45,10117,19,4232,1,0.990724846,0.567054229,1.795778744,1,DB0092410045555_,0,-0.009318436,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,9718,DB01202,10045555,31,6683,32,5686,0.450177549,0.824242884,0.485776345,1.396851952,0.61784236,DB0120210045555_,0.481521935,-0.19329003,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,9725,DB01076,10013700,1934,23813,1031,24552,5.93125079205733e-65,1.93402208,1.788512132,2.092370996,6.11384027722459e-62,DB0107610013700_,140.9497207,0.659601814,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,atorvastatin,DB01076
,9726,DB00776,10013700,68,1837,18,1321,8.21250708910765e-05,2.715860103,1.587566477,4.876981461,0.000674282,DB0077610013700_,7.301862054,0.9991087,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,oxcarbazepine,DB00776
,9727,DB00043,10003553,382,6031,150,2150,0.335018147,0.907881068,0.744668888,1.111201148,0.50419564,DB0004310003553_,0.684790912,-0.096641891,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omalizumab,DB00043
,9731,DB00005,10006825,81,128001,17,42402,0.100949673,1.578318916,0.927450564,2.841335483,0.212217551,DB0000510006825_,1.550143346,0.456360303,NA,10006825,C-reactive protein increased,10022891,Investigations,Inv,etanercept,DB00005
,9734,DB06228,10016173,540,15372,428,15648,0.00015049,1.284321385,1.126959706,1.464367325,0.001130016,DB0622810016173_,6.785523876,0.250230474,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,9741,DB00413,10013573,97,2102,49,1158,0.65921191,1.090548596,0.75955547,1.582848761,0.79180136,DB0041310013573_,0.233444727,0.086680869,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pramipexole,DB00413
,9742,DB00999,10013573,818,20612,394,11845,0.004664075,1.193123222,1.054350699,1.351788815,0.019330685,DB0099910013573_,3.946061561,0.176574426,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,9743,DB00115,10013781,133,18292,44,10428,0.001624739,1.723181445,1.215880705,2.483852461,0.008199392,DB0011510013781_,4.803695277,0.54417226,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,9744,DB00404,10013781,128,19764,37,9825,0.002793349,1.719723898,1.183517433,2.55341405,0.012750401,DB0040410013781_,4.362192559,0.542163754,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,9746,DB00476,10013781,130,17127,28,6149,0.014092091,1.666940647,1.100019759,2.608342961,0.04684591,DB0047610013781_,3.06089157,0.510989999,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,9747,DB00999,10013781,137,21293,55,12184,0.028855346,1.425300737,1.034275323,1.987772656,0.082164747,DB0099910013781_,2.499028935,0.354382835,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,9748,DB00115,10013968,757,17668,423,10049,0.804647708,1.017866798,0.900151243,1.152130184,0.894419007,DB0011510013968_,0.111580926,0.017709063,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,9749,DB00413,10013968,115,2084,39,1168,0.007374117,1.652413894,1.13113355,2.458932058,0.027911103,DB0041310013968_,3.578730703,0.502237185,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pramipexole,DB00413
,9750,DB00404,10015967,52,19840,12,9850,0.015975095,2.15132932,1.132678151,4.430066737,0.051773058,DB0040410015967_,2.96088539,0.766085939,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,alprazolam,DB00404
,9753,DB00999,10015967,62,21368,23,12216,0.089744031,1.541074547,0.940700774,2.607769689,0.194807321,DB0099910015967_,1.635744308,0.432479931,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,hydrochlorothiazide,DB00999
,9754,DB00413,10019211,98,2101,20,1187,8.37656050227498e-06,2.767645926,1.687916904,4.753629886,9.30984747578427e-05,DB0041310019211_,9.281852757,1.017997113,female,10019211,Headache,10029205,Nervous system disorders,Nerv,pramipexole,DB00413
,9755,DB00999,10019211,1054,20376,279,11960,1.74498319046555e-35,2.217370061,1.937532396,2.544286099,5.52613050137192e-33,DB0099910019211_,74.27582023,0.796321836,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,9756,DB00115,10022437,373,18052,195,10277,0.35472147,1.088975812,0.911741691,1.303889896,0.524576957,DB0011510022437_,0.645163137,0.085237632,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,9757,DB00404,10022437,471,19421,208,9654,0.173509186,1.125612469,0.952314038,1.334046922,0.315509405,DB0040410022437_,1.153566789,0.118327304,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,9758,DB00476,10022437,1588,15669,560,5617,0.757922745,1.016549594,0.918111906,1.126689782,0.86479195,DB0047610022437_,0.145266321,0.016414142,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,9759,DB00115,10029410,72,18353,28,10444,0.095393416,1.463284539,0.933015541,2.353837548,0.203854955,DB0011510029410_,1.590346544,0.380683593,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,9760,DB00404,10029410,68,19824,24,9838,0.182711258,1.406079522,0.870752527,2.343665004,0.327325929,DB0040410029410_,1.116798879,0.340805351,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,9762,DB00476,10029410,77,17180,26,6151,0.910775837,1.060319415,0.671258754,1.725389228,0.959816489,DB0047610029410_,0.04101317,0.058570197,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,duloxetine,DB00476
,9763,DB00999,10029410,59,21371,28,12211,0.437417699,1.203940787,0.755147716,1.962188425,0.605850307,DB0099910029410_,0.501122341,0.185600165,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,9765,DB00404,10029412,60,19832,27,9835,0.733052885,1.1020279,0.688360892,1.80692052,0.845100661,DB0040410029412_,0.168299533,0.097152028,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,9767,DB00476,10029412,442,16815,158,6019,1,1.001365548,0.831064762,1.211534189,1,DB0047610029412_,0,0.001364617,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,9768,DB00999,10029412,44,21386,19,12220,0.359359905,1.323235757,0.756257854,2.400975799,0.529105575,DB0099910029412_,0.636567292,0.280080068,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,9774,DB00115,10042682,87,18338,20,10452,0.000107799,2.479272862,1.510546793,4.259787723,0.000850519,DB0011510042682_,7.06966323,0.907965317,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,9775,DB00404,10042682,114,19778,21,9841,5.42795770821197e-06,2.701033508,1.684400669,4.533843706,6.35376835272107e-05,DB0040410042682_,9.663877387,0.99363448,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,9777,DB00476,10042682,72,17185,18,6159,0.188272688,1.43351675,0.845271086,2.556187143,0.334363542,DB0047610042682_,1.095526428,0.360130691,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,9778,DB00999,10042682,116,21314,45,12194,0.026565518,1.474761812,1.036009816,2.131377821,0.077004261,DB0099910042682_,2.563894517,0.388496494,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,9779,DB00019,10000081,91,18921,40,9489,0.516940573,1.14091287,0.777770408,1.700326383,0.676615027,DB0001910000081_,0.390652814,0.131828705,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,pegfilgrastim,DB00019
,9780,DB00526,10000081,93,1505,96,1798,0.33033808,1.157299692,0.85332808,1.569024713,0.499042563,DB0052610000081_,0.69506389,0.14608944,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,oxaliplatin,DB00526
,9781,DB00544,10000081,119,2316,102,2551,0.073450754,1.284976985,0.971902554,1.70135868,0.16727197,DB0054410000081_,1.788134227,0.250740807,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,fluorouracil,DB00544
,9782,DB00650,10000081,91,2040,97,1917,0.412058655,0.881607316,0.650275187,1.194371536,0.581464764,DB0065010000081_,0.542204903,-0.126008543,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,leucovorin,DB00650
,9783,DB00904,10000081,711,22358,332,14124,6.06549815895387e-06,1.352859469,1.183841826,1.548458333,7.0002906304326e-05,DB0090410000081_,9.566973798,0.302220478,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,9784,DB00019,10003988,145,18867,67,9462,0.609467204,1.085353404,0.806167469,1.474043076,0.75189362,DB0001910003988_,0.285160428,0.081905652,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pegfilgrastim,DB00019
,9786,DB00544,10003988,32,2403,42,2611,0.48226863,0.827885518,0.50405701,1.348085295,0.646723684,DB0054410003988_,0.435836148,-0.188880398,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fluorouracil,DB00544
,9787,DB00572,10003988,58,2844,44,2082,0.919416127,0.964986655,0.638120685,1.468335379,0.964382416,DB0057210003988_,0.036267366,-0.035641006,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,atropine,DB00572
,9789,DB00836,10003988,114,5421,54,4021,0.007254467,1.565834013,1.120020245,2.21249828,0.027533561,DB0083610003988_,3.592349621,0.448418597,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,loperamide,DB00836
,9790,DB00019,10013709,89,18923,42,9487,0.781315836,1.062376239,0.727506352,1.57346646,0.880918086,DB0001910013709_,0.126790636,0.060508134,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,9791,DB00526,10013709,33,1565,49,1845,0.369674753,0.794015054,0.491999724,1.267011052,0.539288539,DB0052610013709_,0.617504529,-0.230652858,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,oxaliplatin,DB00526
,9792,DB00544,10013709,77,2358,91,2562,0.637691353,0.919398881,0.66614708,1.266163443,0.774929136,DB0054410013709_,0.254983691,-0.084035212,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fluorouracil,DB00544
,9793,DB00650,10013709,83,2048,61,1953,0.148929348,1.297455092,0.915349809,1.847679664,0.282500391,DB0065010013709_,1.264075343,0.260404724,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,leucovorin,DB00650
,9800,DB00904,10020524,33,23036,25,14431,0.500773541,0.826930991,0.476763947,1.451135785,0.662303985,DB0090410020524_,0.412030636,-0.190034032,NA,10020524,Hydronephrosis,10038359,Renal and urinary disorders,Renal,ondansetron,DB00904
,9808,DB00526,10028813,167,1431,210,1684,0.584237132,0.935830591,0.749798802,1.166727178,0.732054487,DB0052610028813_,0.311900332,-0.066320811,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,oxaliplatin,DB00526
,9809,DB00544,10028813,242,2193,256,2397,0.741117722,1.0332531,0.854787423,1.248631726,0.851502247,DB0054410028813_,0.16075314,0.032712174,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fluorouracil,DB00544
,9810,DB00572,10028813,238,2664,147,1979,0.096074674,1.20269419,0.966770425,1.499919574,0.204869411,DB0057210028813_,1.585382522,0.184564198,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,atropine,DB00572
,9811,DB00650,10028813,217,1914,201,1813,0.836641235,1.022630844,0.831017139,1.258825129,0.915625842,DB0065010028813_,0.088147467,0.022378565,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,leucovorin,DB00650
,9812,DB00836,10028813,454,5081,190,3885,3.19542685615467e-12,1.826909945,1.530769943,2.187039978,1.32062570619537e-10,DB0083610028813_,22.74774529,0.602625985,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,9813,DB00526,10047700,114,1484,143,1751,0.649465787,0.940633098,0.721682326,1.223955929,0.784287431,DB0052610047700_,0.242979705,-0.061202122,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,oxaliplatin,DB00526
,9814,DB00544,10047700,185,2250,196,2457,0.789956758,1.030717486,0.831544867,1.277173364,0.886139185,DB0054410047700_,0.120881248,0.030255148,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,fluorouracil,DB00544
,9815,DB00572,10047700,159,2743,96,2030,0.134566032,1.225684133,0.938978293,1.606710471,0.262053576,DB0057210047700_,1.339206308,0.203499164,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,atropine,DB00572
,9816,DB00650,10047700,164,1967,144,1870,0.515018427,1.082677902,0.852303334,1.376497887,0.674888918,DB0065010047700_,0.393207168,0.079437511,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,leucovorin,DB00650
,9817,DB00836,10047700,287,5248,139,3936,2.98630782503893e-05,1.548490458,1.254645074,1.918262992,0.000282712,DB0083610047700_,8.171080389,0.437280558,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,9818,DB00813,10010305,128,10444,146,10022,0.162023381,0.841296184,0.657201197,1.075823539,0.300066816,DB0081310010305_,1.203750108,-0.172811501,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,fentanyl,DB00813
,9819,DB01067,10010305,40,4321,48,4775,0.74815876,0.920928421,0.588549625,1.434087483,0.856952807,DB0106710010305_,0.15437243,-0.082372964,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,glipizide,DB01067
,9820,DB01590,10010305,37,4701,37,2830,0.030334847,0.602067011,0.37026713,0.978880208,0.085406112,DB0159010010305_,2.460337613,-0.507386527,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,everolimus,DB01590
,9821,DB00327,10011906,342,5796,368,3894,1.65156414461597e-09,0.624423255,0.53430425,0.729559611,4.38941997383526e-08,DB0032710011906_,16.94148365,-0.470926848,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,9822,DB01067,10011906,149,4212,255,4568,1.39066120876809e-05,0.63373408,0.511962868,0.782247684,0.000145169,DB0106710011906_,8.837612643,-0.456125844,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,9823,DB01067,10013968,214,4147,179,4644,0.005253729,1.3387591,1.087566643,1.649544169,0.021276369,DB0106710013968_,3.85015827,0.29174314,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glipizide,DB01067
,9824,DB01590,10013968,200,4538,106,2761,0.278619699,1.147971554,0.898069675,1.473953298,0.442401762,DB0159010013968_,0.815536845,0.137996519,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,everolimus,DB01590
,9826,DB00472,10041349,162,10597,67,4245,0.825273525,0.968579687,0.722550534,1.310624383,0.907590251,DB0047210041349_,0.096962267,-0.031924521,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,9828,DB13867,10041349,46,4504,36,2518,0.133833126,0.714413881,0.45050157,1.140765569,0.261090565,DB1386710041349_,1.34288794,-0.336292819,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,fluticasone,DB13867
,9832,DB00768,10019211,90,1825,17,667,0.013167732,1.934472465,1.133181158,3.493294703,0.044342301,DB0076810019211_,3.115816187,0.659834661,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,olopatadine,DB00768
,9833,DB00950,10019211,299,4419,78,1978,1.85274669449609e-05,1.715724801,1.32499354,2.243376635,0.000186803,DB0095010019211_,8.585457928,0.539835616,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,fexofenadine,DB00950
,9838,DB08908,10010264,50,10623,25,3254,0.054837729,0.61265753,0.371231928,1.035249244,0.134052488,DB0890810010264_,2.009523852,-0.489949177,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,9839,DB00682,10018627,79,19380,82,16282,0.204451401,0.809415392,0.586216622,1.117025312,0.35446514,DB0068210018627_,1.037145274,-0.21144303,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,9841,DB00635,10003988,682,32371,340,23454,1.39055800325805e-08,1.453325812,1.272681655,1.661954568,3.02322722213712e-07,DB0063510003988_,15.01177077,0.373854593,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,9842,DB00635,10033425,986,32067,350,23444,2.40668594569582e-33,2.059553039,1.819074591,2.3362843,6.62405655315337e-31,DB0063510033425_,69.48942993,0.722488988,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,9843,DB00005,10017853,62,128020,15,42404,0.355386314,1.369060185,0.769585704,2.591715561,0.525132201,DB0000510017853_,0.644105237,0.314124508,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,9850,DB00412,10051592,31,1033,49,1337,0.423428131,0.818901904,0.500926209,1.320809061,0.592263113,DB0041210051592_,0.523804295,-0.199790977,NA,10051592,Acute coronary syndrome,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,9854,DB00005,10037855,451,127631,110,42309,0.003319948,1.359107074,1.100803608,1.690239675,0.014684869,DB0000510037855_,4.220937632,0.306827921,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,9855,DB01202,10054112,52,6662,53,5665,0.376936474,0.834315413,0.557009869,1.249153571,0.54683198,DB0120210054112_,0.60361369,-0.181143755,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,levetiracetam,DB01202
,9857,DB00654,10013709,180,3636,117,2481,0.716728256,1.049757921,0.822314875,1.344212711,0.83251017,DB0065410013709_,0.183309841,0.048559586,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,9858,DB00331,10003658,194,24752,274,20478,1.07092900874104e-08,0.585786795,0.484374116,0.707321188,2.39467196892883e-07,DB0033110003658_,15.24484939,-0.534799387,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,metformin,DB00331
,9860,DB00331,10056819,66,24880,53,20699,0.92660578,1.03602235,0.710392988,1.51717122,0.968885072,DB0033110056819_,0.031609279,0.035388716,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,9862,DB00005,10040829,487,127595,153,42266,0.582922834,1.054350057,0.877172236,1.273311314,0.731034934,DB0000510040829_,0.313294031,0.052924518,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,9869,DB00381,10023676,105,29255,117,22770,0.008124201,0.698513719,0.531245976,0.917508626,0.030165933,DB0038110023676_,3.501042054,-0.35880046,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,9871,DB00335,10033295,101,8365,64,5401,0.936221578,1.018941853,0.73622221,1.419063175,0.976376138,DB0033510033295_,0.02390738,0.018764689,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,atenolol,DB00335
,9872,DB00381,10033295,240,29120,230,22657,0.025012588,0.811892185,0.674125159,0.977955367,0.073498124,DB0038110033295_,2.610495392,-0.208387725,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,9874,DB00177,10037423,19,4781,32,2818,0.000231592,0.350015675,0.187056743,0.637963174,0.001628296,DB0017710037423_,6.420221097,-1.04977734,male,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,valsartan,DB00177
,9875,DB00335,10037423,35,8431,53,5412,6.93291375477362e-05,0.423930883,0.268094548,0.66294836,0.000582396,DB0033510037423_,7.448360315,-0.858184848,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atenolol,DB00335
,9876,DB00381,10037423,182,29178,220,22667,1.07050951041118e-05,0.642684699,0.524735664,0.786324503,0.000115132,DB0038110037423_,9.069428359,-0.442101034,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,9878,DB00177,10038435,45,4755,50,2800,0.002604121,0.529999101,0.345286154,0.81151498,0.012043515,DB0017710038435_,4.419228926,-0.634879969,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,valsartan,DB00177
,9879,DB00335,10038435,93,8373,68,5397,0.4651222,0.881557468,0.636623424,1.22599925,0.631951671,DB0033510038435_,0.458942357,-0.126065086,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,atenolol,DB00335
,9886,DB00264,10001551,87,29520,99,24793,0.039174377,0.738078357,0.546647172,0.995053402,0.10397319,DB0026410001551_,2.263622201,-0.303705285,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,metoprolol,DB00264
,9887,DB00425,10001551,39,12656,32,7452,0.176275615,0.71764821,0.437684023,1.184423847,0.319050063,DB0042510001551_,1.142407251,-0.331775789,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,zolpidem,DB00425
,9888,DB00722,10001551,70,25333,71,25961,1,1.01035681,0.715432784,1.42653668,1,DB0072210001551_,0,0.010303546,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,lisinopril,DB00722
,9889,DB00741,10001551,35,4059,23,3151,0.596017245,1.18129758,0.676994776,2.09862459,0.741460234,DB0074110001551_,0.299133748,0.166613479,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,hydrocortisone,DB00741
,9890,DB01076,10001551,96,25651,142,25441,0.002729769,0.670530407,0.51174184,0.875404261,0.012516701,DB0107610001551_,4.380691429,-0.399686228,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,atorvastatin,DB01076
,9891,DB09037,10001551,37,2489,30,2805,0.217908309,1.389820501,0.832709908,2.336939608,0.371074465,DB0903710001551_,0.991352522,0.329174603,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,pembrolizumab,DB09037
,9892,DB00264,10003481,95,29512,85,24807,0.70808377,0.93948903,0.693333172,1.274719501,0.825584719,DB0026410003481_,0.191663393,-0.062419136,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,metoprolol,DB00264
,9893,DB00425,10003481,41,12654,29,7455,0.458938429,0.832940282,0.504755053,1.39098925,0.626333922,DB0042510003481_,0.467871628,-0.18279333,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,zolpidem,DB00425
,9894,DB00722,10003481,78,25325,68,25964,0.362029179,1.175996306,0.838163174,1.653417006,0.531735413,DB0072210003481_,0.631609256,0.162115708,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,lisinopril,DB00722
,9895,DB00741,10003481,34,4060,20,3154,0.338993865,1.320589642,0.737024886,2.426215163,0.508057234,DB0074110003481_,0.677161171,0.278078335,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,hydrocortisone,DB00741
,9896,DB01076,10003481,92,25655,126,25457,0.020832923,0.72453104,0.547343952,0.956087663,0.063814635,DB0107610003481_,2.751772726,-0.322230674,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,atorvastatin,DB01076
,9897,DB09037,10003481,40,2486,28,2807,0.065931778,1.612873046,0.967329649,2.723283452,0.154038517,DB0903710003481_,1.870552598,0.478017089,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,pembrolizumab,DB09037
,9904,DB00196,10013709,206,4877,159,3126,0.089349779,0.830461441,0.66858264,1.033072856,0.194208131,DB0019610013709_,1.638824854,-0.18577378,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,9907,DB00624,10016256,32,530,237,4159,0.766567237,1.059534975,0.700664033,1.556566722,0.871524896,DB0062410016256_,0.137510848,0.057830109,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,testosterone,DB00624
,9908,DB00005,10037876,277,127805,72,42347,0.072057516,1.274729551,0.980079383,1.676368913,0.16488481,DB0000510037876_,1.802508168,0.242734039,NA,10037876,Rash papular,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,9909,DB00005,10041349,393,127689,131,42288,0.959642568,0.993538942,0.813009441,1.220596257,0.997280074,DB0000510041349_,0.002723632,-0.006482021,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,9910,DB00820,10003239,425,11490,158,5658,0.002643305,1.324573052,1.0976857,1.604793302,0.012193625,DB0082010003239_,4.406841999,0.281090183,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,9911,DB00559,10021097,324,9335,83,3223,0.015259628,1.347704235,1.052149432,1.742616432,0.049974996,DB0055910021097_,2.99623248,0.298402578,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,bosentan,DB00559
,9912,DB00820,10021097,606,11309,197,5619,1.93551317208914e-07,1.528380489,1.294980103,1.809957167,3.29501060416858e-06,DB0082010021097_,12.62310117,0.424208671,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,tadalafil,DB00820
,9913,DB00820,10025482,876,11039,226,5590,1.38769943566274e-20,1.962739002,1.687597399,2.28994891,1.54557964688115e-18,DB0082010025482_,41.01113266,0.674340948,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,9914,DB00559,10037660,314,9345,130,3176,0.067416201,0.820884001,0.664236172,1.019131727,0.15672709,DB0055910037660_,1.853249264,-0.197373469,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,9915,DB00820,10037660,418,11497,156,5660,0.003294643,1.319124484,1.091767998,1.600247835,0.014598734,DB0082010037660_,4.226820492,0.276968247,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,9916,DB00007,10012174,13,1934,70,4382,0.002519459,0.420832612,0.213022164,0.76950579,0.011729362,DB0000710012174_,4.445659992,-0.86552012,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,leuprolide,DB00007
,9917,DB00115,10012174,292,18133,188,10284,0.18029157,0.880889199,0.729628583,1.065526805,0.324220157,DB0011510012174_,1.126332498,-0.126823429,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,cyanocobalamin,DB00115
,9918,DB00455,10012174,130,9271,85,5033,0.195572466,0.830301878,0.625444421,1.107096722,0.343739369,DB0045510012174_,1.067871558,-0.185965936,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,loratadine,DB00455
,9920,DB00999,10012174,356,21074,203,12036,1,1.001588074,0.839356199,1.197750344,1,DB0099910012174_,0,0.001586815,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,9921,DB01062,10012174,57,4429,24,1721,0.710630601,0.922881728,0.561523696,1.560224486,0.827428337,DB0106210012174_,0.189432778,-0.080254191,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,oxybutynin,DB01062
,9924,DB13961,10012174,100,9357,93,6321,0.032078832,0.726412155,0.541180212,0.975832461,0.089283364,DB1396110012174_,2.415940106,-0.319637719,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,fish oil,DB13961
,9925,DB00007,10013573,49,1898,129,4323,0.410143818,0.865183373,0.606756325,1.216843348,0.579541462,DB0000710013573_,0.545518072,-0.144813802,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,leuprolide,DB00007
,9926,DB00627,10013573,38,1291,50,1549,0.744593442,0.911940182,0.577930048,1.428723987,0.854143649,DB0062710013573_,0.157655892,-0.092180881,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,niacin,DB00627
,9930,DB13961,10013573,380,9077,214,6200,0.026706869,1.212861886,1.019804345,1.445426289,0.077358537,DB1396110013573_,2.559304342,0.192982762,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,9932,DB00115,10020646,24,18401,32,10440,0.001905409,0.425529667,0.239675954,0.745983127,0.009353569,DB0011510020646_,4.671997291,-0.854420612,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,cyanocobalamin,DB00115
,9935,DB00999,10020646,28,21402,68,12171,1.1643415213783e-11,0.234177833,0.145101248,0.368862161,4.40672669394222e-10,DB0099910020646_,21.54271876,-1.451674483,male,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,9941,DB00007,10020772,28,1919,55,4397,0.548335708,1.166432583,0.710073731,1.877489568,0.702781972,DB0000710020772_,0.352708575,0.153950016,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,leuprolide,DB00007
,9942,DB00115,10020772,248,18177,126,10346,0.329797695,1.120305384,0.899185053,1.401436864,0.498446507,DB0011510020772_,0.696259004,0.113601313,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,cyanocobalamin,DB00115
,9943,DB00455,10020772,134,9267,56,5062,0.108183341,1.307062635,0.948086561,1.822527586,0.223325149,DB0045510020772_,1.499126501,0.267782356,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,loratadine,DB00455
,9945,DB01062,10020772,76,4410,25,1720,0.504220656,1.185629598,0.742961465,1.9518894,0.665344538,DB0106210020772_,0.40745027,0.17027394,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,oxybutynin,DB01062
,9949,DB13961,10020772,124,9333,83,6331,0.943299876,1.013431704,0.75985382,1.357418679,0.98221868,DB1396110020772_,0.017941307,0.013342298,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,fish oil,DB13961
,9951,DB00115,10030124,236,18189,121,10351,0.375579785,1.10995242,0.886512131,1.395552918,0.545420699,DB0011510030124_,0.606197858,0.10431715,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,9953,DB00999,10030124,301,21129,135,12104,0.018499417,1.277277092,1.037825686,1.578618606,0.058095243,DB0099910030124_,2.845671499,0.24473054,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,9957,DB13961,10030124,136,9321,72,6342,0.088229588,1.285177919,0.957048508,1.737929536,0.192309037,DB1396110030124_,1.648651632,0.250897167,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,9959,DB00115,10043071,74,18351,38,10434,0.693769644,1.10724321,0.738448342,1.684516007,0.815624613,DB0011510043071_,0.203801064,0.101873332,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,cyanocobalamin,DB00115
,9960,DB00455,10043071,53,9348,24,5094,0.475986769,1.20334013,0.728959288,2.040952083,0.641432955,DB0045510043071_,0.444050613,0.185101132,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,loratadine,DB00455
,9966,DB13961,10043071,38,9419,21,6393,0.507476463,1.228156815,0.701962883,2.205072078,0.668120151,DB1396110043071_,0.403287255,0.205514521,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,fish oil,DB13961
,9967,DB06616,10012735,320,641,242,561,0.166000362,1.157185103,0.941135802,1.423760902,0.305436947,DB0661610012735_,1.186011914,0.145990421,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,bosutinib,DB06616
,9968,DB06616,10028813,184,777,102,701,0.000272363,1.627021912,1.242635946,2.138856605,0.001864502,DB0661610028813_,6.284761142,0.486751296,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,bosutinib,DB06616
,9971,DB00661,10053762,108,3420,40,1555,0.321621402,1.227558404,0.842110173,1.820807822,0.489906036,DB0066110053762_,0.71354167,0.20502716,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,verapamil,DB00661
,9973,DB01115,10013700,240,3360,83,2185,5.16820571619589e-07,1.880184008,1.450033299,2.45798294,7.98391344403227e-06,DB0111510013700_,11.73808186,0.631369649,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,nifedipine,DB01115
,9974,DB00318,10028813,184,4099,40,1799,2.8845494338367e-05,2.018682965,1.420351038,2.930949702,0.000274157,DB0031810028813_,8.201808755,0.702445301,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,codeine,DB00318
,9975,DB01115,10028813,241,3359,81,2187,1.87320870029337e-07,1.936973902,1.490636135,2.53832479,3.20346718849779e-06,DB0111510028813_,12.65127684,0.661126911,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,nifedipine,DB01115
,9976,DB00318,10047700,135,4148,24,1815,1.437831879155e-05,2.46098113,1.579426397,3.988775514,0.000149529,DB0031810047700_,8.808021363,0.900560104,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,codeine,DB00318
,9977,DB01115,10047700,143,3457,42,2226,3.48841575563556e-06,2.192090841,1.537249255,3.184232114,4.30989462453023e-05,DB0111510047700_,10.05201201,0.78485581,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,nifedipine,DB01115
,9978,DB00422,10013654,47,3388,25,2924,0.056821251,1.622402556,0.975748634,2.757965177,0.137470348,DB0042210013654_,1.984347037,0.48390811,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,methylphenidate,DB00422
,9999,DB00343,10011224,262,8474,83,5012,3.18634182419577e-07,1.866926905,1.449417642,2.425693301,5.15720411631686e-06,DB0034310011224_,12.17511596,0.624293713,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,10002,DB01156,10010071,58,13564,33,6295,0.366923919,0.815712729,0.522546072,1.292718593,0.536556062,DB0115610010071_,0.622584226,-0.203693033,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,10003,DB01156,10022523,289,13333,199,6129,2.15818697751777e-05,0.667591152,0.553928502,0.805844648,0.000213143,DB0115610022523_,8.453548397,-0.40407934,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,10004,DB01156,10035669,27,13595,49,6279,6.20378633933464e-09,0.254520095,0.152801767,0.415689281,1.46313615010687e-07,DB0115610035669_,15.73751347,-1.368375486,male,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,bupropion,DB01156
,10006,DB01156,10040752,62,13560,12,6316,0.003683866,2.406451046,1.283173572,4.909833019,0.015968077,DB0115610040752_,4.137163711,0.878153067,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,bupropion,DB01156
,10007,DB01156,10041962,119,13503,94,6234,0.000147697,0.584470819,0.441464485,0.775714374,0.001111427,DB0115610041962_,6.802110833,-0.537048424,NA,10041962,Status epilepticus,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,10012,DB00402,10011906,44,1308,40,656,0.009323514,0.55182863,0.347526913,0.878510012,0.03364709,DB0040210011906_,3.391828712,-0.594517735,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,eszopiclone,DB00402
,10013,DB00497,10011906,1322,17945,1312,15063,3.7030240982425e-05,0.845802254,0.780624785,0.91644293,0.000341223,DB0049710011906_,7.982973024,-0.167469689,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,10014,DB00697,10011906,155,5941,91,1715,4.00079430360923e-07,0.491729964,0.374951723,0.647951037,6.32546636212743e-06,DB0069710011906_,11.97092679,-0.709825566,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,10015,DB00996,10011906,1411,37542,1148,21277,1.28244115320872e-18,0.696622447,0.642751759,0.755051317,1.17452842202408e-16,DB0099610011906_,36.68049476,-0.361511698,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,10022,DB00227,10003549,83,2384,57,1746,0.728788073,1.066449662,0.747561918,1.530410415,0.841882504,DB0022710003549_,0.172114819,0.064335059,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,lovastatin,DB00227
,10023,DB00341,10003549,264,11141,139,4929,0.101438939,0.840304548,0.679750413,1.042394546,0.21304163,DB0034110003549_,1.546267685,-0.173990896,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,10024,DB00612,10003549,36,1104,25,615,0.417196713,0.802289524,0.463545434,1.408407986,0.586339559,DB0061210003549_,0.533856205,-0.220285734,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,bisoprolol,DB00612
,10026,DB14500,10003549,340,7469,166,3907,0.502891108,1.071400448,0.883570757,1.303121967,0.664033677,DB1450010003549_,0.409422412,0.068966623,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,10027,DB00227,10013573,87,2380,42,1761,0.02381349,1.532533691,1.042788766,2.282927369,0.070811423,DB0022710013573_,2.647734946,0.426922373,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lovastatin,DB00227
,10028,DB00341,10013573,376,11029,155,4913,0.444620965,1.08059798,0.891030256,1.315518167,0.612679532,DB0034110013573_,0.489913266,0.077514573,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,10029,DB00588,10013573,607,15917,233,8235,0.00011302,1.347814706,1.154113366,1.578129104,0.000886256,DB0058810013573_,7.028504924,0.298484544,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,10030,DB00612,10013573,38,1102,25,615,0.593096696,0.848363318,0.493615554,1.481355268,0.739243979,DB0061210013573_,0.302127265,-0.164446294,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,bisoprolol,DB00612
,10032,DB00905,10013573,44,2674,16,909,0.881090826,0.934847187,0.514207146,1.783944326,0.950229659,DB0090510013573_,0.051051578,-0.067372199,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,bimatoprost,DB00905
,10033,DB14500,10013573,319,7490,125,3948,0.005866755,1.345134246,1.086331932,1.67387396,0.023259047,DB1450010013573_,3.761061105,0.29649382,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,potassium,DB14500
,10035,DB00316,10013836,33,65441,23,36930,0.486756286,0.809697795,0.461204252,1.44439155,0.650633831,DB0031610013836_,0.429808266,-0.211094193,NA,10013836,Duodenal ulcer,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,10044,DB00316,10016100,80,65394,52,36901,0.468209315,0.868140621,0.604595863,1.256012793,0.634767993,DB0031610016100_,0.454495712,-0.141401572,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,10055,DB00204,10013700,41,923,12,1031,1.73850637859806e-05,3.814233394,1.952040195,8.021176804,0.000176469,DB0020410013700_,8.642365496,1.338739699,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,dofetilide,DB00204
,10056,DB00413,10013700,61,2138,13,1194,0.000827574,2.61986309,1.416679545,5.219861704,0.004708906,DB0041310013700_,5.358299645,0.963122061,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,pramipexole,DB00413
,10058,DB00575,10013700,132,5112,42,3787,7.90822271653574e-07,2.32802054,1.629173306,3.387021334,1.1648508495609e-05,DB0057510013700_,11.36033241,0.845018353,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,clonidine,DB00575
,10060,DB00804,10013700,106,2894,11,888,0.000195105,2.956368754,1.577682758,6.130126754,0.001411012,DB0080410013700_,6.563447877,1.083961743,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,dicyclomine,DB00804
,10062,DB01224,10013700,160,7948,40,5877,3.86623408322976e-11,2.957460675,2.0764026,4.301296717,1.34958782042091e-09,DB0122410013700_,20.42346661,1.08433102,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,quetiapine,DB01224
,10063,DB00005,10022062,640,127442,244,42175,0.06126372,0.868046646,0.747531783,1.010575067,0.145763013,DB0000510022062_,1.925773176,-0.141509827,NA,10022062,Injection site extravasation,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,10066,DB08895,10033775,299,27815,53,6593,0.056149056,1.33719424,0.994342697,1.828770134,0.136358658,DB0889510033775_,1.992466673,0.290573568,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,10070,DB00334,10033295,64,2785,94,2718,0.012409664,0.664523349,0.473767277,0.927072165,0.042274299,DB0033410033295_,3.163575963,-0.408685264,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,olanzapine,DB00334
,10072,DB00334,10070863,223,2626,210,2602,0.617365177,1.052210966,0.860615028,1.286716488,0.758398078,DB0033410070863_,0.276546862,0.050893632,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,olanzapine,DB00334
,10075,DB00005,10040831,350,127732,143,42276,0.036816943,0.810065232,0.664783115,0.99137765,0.099219084,DB0000510040831_,2.310424904,-0.210640501,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,10076,DB00091,10013709,392,5118,192,2478,0.89084736,0.988518037,0.823959177,1.188991471,0.954680373,DB0009110013709_,0.046378682,-0.01154839,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,10077,DB00254,10013709,221,5714,181,3207,0.000302295,0.685344397,0.55774556,0.842901773,0.00202996,DB0025410013709_,6.19973895,-0.377833798,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,10079,DB00557,10013709,292,5695,106,2961,0.001659325,1.432205555,1.137587623,1.81425889,0.008343447,DB0055710013709_,4.786278886,0.359215602,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,10080,DB00563,10013709,11192,35454,3073,12275,1.2784769381662e-24,1.260930623,1.205401714,1.31929561,1.90395276598858e-22,DB0056310013709_,50.01293992,0.231850038,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,10081,DB00688,10013709,286,6204,211,5167,0.197594982,1.128861754,0.937893276,1.36043016,0.346057852,DB0068810013709_,1.061149317,0.121209828,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,10082,DB00787,10013709,339,16661,345,16903,0.969214428,0.996881042,0.854210368,1.163314519,1,DB0078710013709_,0,-0.003123832,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,10083,DB01611,10013709,2043,9870,357,2004,0.015962223,1.161914942,1.02719211,1.316823146,0.051740761,DB0161110013709_,2.961509395,0.150069456,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,10084,DB00051,10031282,58,25673,6,11414,6.49132458079997e-05,4.29794841,1.858662686,12.1938411,0.000550347,DB0005110031282_,7.504961426,1.458137795,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,10090,DB00563,10031282,96,46550,17,15331,0.016022212,1.859720531,1.102695238,3.324974774,0.051877783,DB0056310031282_,2.958864655,0.620426224,NA,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,10091,DB00635,10031282,121,32932,47,23747,0.000217582,1.856400297,1.314617251,2.659774657,0.001546971,DB0063510031282_,6.471456721,0.618639288,NA,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,10095,DB01611,10031282,51,11862,8,2353,0.724695986,1.264553477,0.594669961,3.089692495,0.838481996,DB0161110031282_,0.17616217,0.234719077,NA,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,10096,DB00051,10043414,144,25587,51,11369,0.185738246,1.254537213,0.90491463,1.763818835,0.331115317,DB0005110043414_,1.105288575,0.22676675,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,10100,DB00497,10043414,37,19230,29,16346,0.805231536,1.084543016,0.648728523,1.829318598,0.894590507,DB0049710043414_,0.1113892,0.081158714,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,10102,DB00563,10043414,220,46426,98,15250,0.013321915,0.737407548,0.578221008,0.946131178,0.044738281,DB0056310043414_,3.106925738,-0.304614557,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,10103,DB00635,10043414,119,32934,79,23715,0.613742199,1.084689253,0.808908679,1.461178644,0.755369411,DB0063510043414_,0.280548363,0.081293543,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,10106,DB00959,10043414,33,8045,42,4960,0.00185573,0.484437339,0.297081272,0.784074422,0.009150432,DB0095910043414_,4.693954201,-0.724767188,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,10107,DB01611,10043414,57,11856,10,2351,0.869197005,1.130267788,0.57102541,2.486251832,0.941834294,DB0161110043414_,0.059925929,0.122454585,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,10116,DB00028,10010264,66,13392,46,5569,0.009032639,0.596665328,0.402771249,0.890458503,0.032818151,DB0002810010264_,3.416773521,-0.516398913,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,10117,DB00959,10010264,190,7888,120,4882,0.859391639,0.979941315,0.773374392,1.245704229,0.933395696,DB0095910010264_,0.068926056,-0.020262592,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,10124,DB00264,10003988,542,29065,390,24502,0.018513478,1.171559669,1.02551386,1.339341045,0.058135926,DB0026410003988_,2.844971455,0.158335911,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,10125,DB01590,10003988,67,4671,56,2811,0.074989469,0.720060964,0.495756135,1.049217052,0.169806853,DB0159010003988_,1.773093647,-0.328419398,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,everolimus,DB01590
,10130,DB00555,10000081,93,6954,21,3465,0.000609637,2.206501531,1.360164842,3.737955532,0.003647693,DB0055510000081_,5.613660244,0.791408243,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,lamotrigine,DB00555
,10132,DB01202,10000081,66,6648,52,5666,0.710994888,1.081769885,0.739328599,1.589935951,0.827675574,DB0120210000081_,0.18913402,0.078598483,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,levetiracetam,DB01202
,10141,DB00252,10012735,44,2188,22,1886,0.04565205,1.72372543,1.006934073,3.031786796,0.116818937,DB0025210012735_,2.147130087,0.544487896,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,phenytoin,DB00252
,10142,DB00555,10012735,180,6867,77,3409,0.314062289,1.160461313,0.880886518,1.540911321,0.481615312,DB0055510012735_,0.730609591,0.14881761,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lamotrigine,DB00555
,10144,DB01202,10012735,213,6501,136,5582,0.007586741,1.344743034,1.076035432,1.685183339,0.028547346,DB0120210012735_,3.556191301,0.296202942,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,levetiracetam,DB01202
,10157,DB00252,10021097,58,2174,22,1886,0.000906046,2.286604644,1.37213236,3.939569104,0.00508008,DB0025210021097_,5.282428311,0.827068029,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,phenytoin,DB00252
,10158,DB00555,10021097,94,6953,44,3442,0.785616321,1.057575133,0.729902623,1.553012577,0.883734037,DB0055510021097_,0.123599125,0.055978677,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,lamotrigine,DB00555
,10159,DB01174,10021097,36,903,23,769,0.352147951,1.332727975,0.760901665,2.377829103,0.521888187,DB0117410021097_,0.650301916,0.287227951,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,phenobarbital,DB01174
,10160,DB01202,10021097,124,6590,120,5598,0.330735243,0.877794863,0.675577262,1.140819122,0.499459934,DB0120210021097_,0.694227895,-0.130342354,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,levetiracetam,DB01202
,10161,DB00252,10028813,69,2163,40,1868,0.051301044,1.48959212,0.989449927,2.269145238,0.127452547,DB0025210028813_,2.060011161,0.398502337,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,phenytoin,DB00252
,10163,DB01202,10028813,309,6405,205,5513,0.005032422,1.297369662,1.079768488,1.561376917,0.020570286,DB0120210028813_,3.883907691,0.260338878,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,levetiracetam,DB01202
,10171,DB01202,10033661,47,6667,31,5687,0.305350778,1.293241056,0.803372162,2.108752995,0.472153228,DB0120210033661_,0.750451711,0.257151514,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,levetiracetam,DB01202
,10172,DB00252,10037660,57,2175,37,1871,0.209323492,1.325127885,0.856651169,2.07182618,0.360369381,DB0025210037660_,1.020625715,0.281508972,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,phenytoin,DB00252
,10173,DB00555,10037660,131,6916,71,3415,0.546121049,0.911074403,0.675284449,1.237716491,0.700746486,DB0055510037660_,0.355609104,-0.093130714,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,10175,DB01202,10037660,162,6552,187,5531,0.00455454,0.731337276,0.587038024,0.910296407,0.018951413,DB0120210037660_,3.965876777,-0.312880536,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,10176,DB00252,10037844,76,2156,41,1867,0.018319447,1.605002377,1.07785248,2.419947243,0.057643703,DB0025210037844_,2.853474259,0.473125237,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,phenytoin,DB00252
,10178,DB01202,10037844,140,6574,102,5616,0.241206247,1.172517962,0.899615622,1.532505698,0.399358334,DB0120210037844_,0.917896185,0.159153541,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,levetiracetam,DB01202
,10184,DB00555,10043071,90,6957,44,3442,1,1.011994771,0.696389596,1.48987751,1,DB0055510043071_,0,0.011923404,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,lamotrigine,DB00555
,10186,DB01202,10043071,96,6618,43,5675,0.000306371,1.914311544,1.320282725,2.815871982,0.002052753,DB0120210043071_,6.188573304,0.649358051,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,levetiracetam,DB01202
,10190,DB01202,10043554,62,6652,54,5664,0.925617742,0.977613702,0.66656141,1.437750472,0.968256387,DB0120210043554_,0.032258365,-0.022640674,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,levetiracetam,DB01202
,10191,DB00252,10047700,62,2170,36,1872,0.064997302,1.485571383,0.964838745,2.317753841,0.152445264,DB0025210047700_,1.88094967,0.395799468,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,phenytoin,DB00252
,10192,DB00555,10047700,216,6831,94,3392,0.326958317,1.141007126,0.888207923,1.474874329,0.495363844,DB0055510047700_,0.702462748,0.131911316,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lamotrigine,DB00555
,10194,DB01202,10047700,212,6502,123,5595,0.000556339,1.483095615,1.178504174,1.873025218,0.003371771,DB0120210047700_,5.692317095,0.394131535,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,levetiracetam,DB01202
,10203,DB00252,10073508,95,2137,35,1873,6.37982468395588e-06,2.378395064,1.589833775,3.63090187,7.32606779457319e-05,DB0025210073508_,9.521486547,0.866425918,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,phenytoin,DB00252
,10204,DB00555,10073508,130,6917,73,3413,0.407432488,0.878713817,0.652647258,1.190678462,0.576908316,DB0055510073508_,0.550071923,-0.129296012,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,lamotrigine,DB00555
,10205,DB01174,10073508,66,873,18,774,2.83719946170685e-06,3.248601997,1.885889717,5.868652414,3.60848133684321e-05,DB0117410073508_,10.22963846,1.178224749,female,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,phenobarbital,DB01174
,10206,DB01202,10073508,101,6613,47,5671,0.000462151,1.842735219,1.288735608,2.668401935,0.002892169,DB0120210073508_,5.845748514,0.611251,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,levetiracetam,DB01202
,10209,DB14509,10070863,112,773,74,477,0.686580068,0.933998683,0.674374279,1.2991563,0.810962639,DB1450910070863_,0.209533294,-0.068280251,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,lithium carbonate,DB14509
,10210,DB00028,10003988,224,13234,73,5542,0.072159309,1.284945919,0.980568639,1.700557437,0.165045895,DB0002810003988_,1.801531693,0.250716631,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,human immunoglobulin g,DB00028
,10211,DB00959,10003988,193,7885,83,4919,0.004782783,1.450582401,1.112948649,1.904374975,0.019744849,DB0095910003988_,3.924862645,0.371965132,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,methylprednisolone,DB00959
,10228,DB00295,10033371,563,14100,354,9248,0.558487651,1.043121814,0.909207062,1.197977512,0.71138804,DB0029510033371_,0.340537232,0.042217961,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,10229,DB00181,10013968,271,9585,141,5730,0.197036477,1.149001112,0.93135349,1.422336615,0.345457831,DB0018110013968_,1.062884695,0.138892967,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,baclofen,DB00181
,10231,DB00181,10033295,252,9604,219,5652,3.79389524864975e-05,0.677226518,0.561053344,0.817853248,0.000348863,DB0018110033295_,7.960830781,-0.38974947,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,10232,DB00181,10033425,264,9592,100,5771,7.47781757816395e-05,1.588303745,1.254059012,2.024633385,0.000621123,DB0018110033425_,7.383981114,0.46266662,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,10233,DB00181,10005734,30,9826,25,5846,0.212176526,0.713979897,0.405454192,1.267405039,0.36399034,DB0018110005734_,1.010627949,-0.336900473,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,baclofen,DB00181
,10234,DB00181,10038687,30,9826,23,5848,0.394103511,0.776317246,0.435526372,1.400857937,0.564047305,DB0018110038687_,0.572617157,-0.25319402,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,baclofen,DB00181
,10235,DB00181,10045555,112,9744,95,5776,0.011314314,0.698890259,0.525866475,0.930398968,0.039268074,DB0018110045555_,3.237343465,-0.358261547,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,10236,DB08890,10012735,201,1746,61,498,0.695165245,0.939852804,0.689479162,1.295365511,0.816560818,DB0889010012735_,0.202653883,-0.062032008,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,linaclotide,DB08890
,10238,DB00230,10003549,457,19217,206,8445,0.765303561,0.974906903,0.823537936,1.157210811,0.870521783,DB0023010003549_,0.138662497,-0.025413297,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,10239,DB00423,10003549,58,2409,35,1005,0.10643829,0.691413681,0.443688308,1.091239102,0.220766868,DB0042310003549_,1.510648029,-0.369016964,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,methocarbamol,DB00423
,10240,DB00425,10003549,354,12341,234,7250,0.179200438,0.888748913,0.749361003,1.055601676,0.322876479,DB0042510003549_,1.130485447,-0.11794052,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,10241,DB00455,10003549,261,9140,144,4974,0.916003807,0.986360717,0.799246891,1.221145571,0.962412714,DB0045510003549_,0.038311904,-0.013733153,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,10243,DB01068,10003549,346,13417,159,6681,0.416547088,1.083583644,0.893342718,1.318928831,0.585771083,DB0106810003549_,0.534826209,0.080273737,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,10244,DB01175,10003549,288,10436,136,4756,0.750176184,0.965096296,0.781981492,1.195804246,0.858608826,DB0117510003549_,0.152441843,-0.035527394,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,10245,DB06700,10003549,58,2167,13,605,0.561075801,1.24551139,0.668949671,2.494903504,0.713574646,DB0670010003549_,0.337468228,0.219546201,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,desvenlafaxine,DB06700
,10246,DB00230,10013887,65,19609,30,8621,0.823921931,0.952566582,0.608599532,1.522299039,0.90669184,DB0023010013887_,0.097952644,-0.048595272,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,10247,DB00316,10013887,123,65351,89,36864,0.073936559,0.779606788,0.588492971,1.036222727,0.168073064,DB0031610013887_,1.783356492,-0.248965604,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,10249,DB00425,10013887,40,12655,19,7465,0.500779737,1.24188344,0.70203208,2.271987343,0.662303985,DB0042510013887_,0.412030636,0.21662913,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,10252,DB00999,10013887,49,21381,38,12201,0.18010312,0.735862894,0.471614642,1.155938885,0.323925589,DB0099910013887_,1.127241454,-0.306711463,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,10253,DB01050,10013887,50,18058,22,9349,0.618801996,1.176613575,0.699012651,2.041812173,0.759701563,DB0105010013887_,0.274829603,0.162640461,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,10254,DB01068,10013887,76,13687,38,6802,1,0.993934941,0.664071663,1.510066359,1,DB0106810013887_,0,-0.006083527,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,10259,DB00230,10019211,999,18675,224,8427,3.89788346135602e-23,2.0124281,1.73512651,2.342076788,5.33624306154911e-21,DB0023010019211_,46.67976509,0.699342003,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,10260,DB00423,10019211,131,2336,20,1020,1.71472802536213e-06,2.859338725,1.76588471,4.862186247,2.31471699290583e-05,DB0042310019211_,10.67363803,1.050590383,female,10019211,Headache,10029205,Nervous system disorders,Nerv,methocarbamol,DB00423
,10261,DB00455,10019211,512,8889,119,4999,3.08093108369512e-20,2.4195203,1.971876413,2.988170627,3.25230014196491e-18,DB0045510019211_,40.26716919,0.883569297,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,10262,DB00783,10019211,988,15726,11,362,0.013537727,2.067599681,1.136607932,4.193129622,0.045309626,DB0078310019211_,3.094235778,0.72638836,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,estradiol,DB00783
,10263,DB01050,10019211,1054,17054,331,9040,3.2141311803583e-17,1.687900698,1.486372386,1.920612534,2.5485200022841e-15,DB0105010019211_,33.6032636,0.523485566,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,10264,DB01068,10019211,747,13016,200,6640,6.70252791896031e-17,1.905323194,1.623113014,2.24472303,5.08444289610019e-15,DB0106810019211_,32.91259093,0.64465165,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,10265,DB01175,10019211,543,10181,154,4738,3.95705801898334e-08,1.640858384,1.364788432,1.982095456,7.79694677878389e-07,DB0117510019211_,14.06436343,0.49521951,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,10266,DB06700,10019211,146,2079,20,598,0.001296988,2.099415728,1.296894019,3.569805697,0.006814332,DB0670010019211_,4.988727304,0.741659081,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,desvenlafaxine,DB06700
,10267,DB13867,10019211,274,4276,93,2461,9.5383415060268e-06,1.695552323,1.328004445,2.180564267,0.000104378,DB1386710019211_,9.167494223,0.528008542,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,fluticasone,DB13867
,10268,DB00230,10020772,231,19443,99,8552,0.857065788,1.026335315,0.806380993,1.31418367,0.931434447,DB0023010020772_,0.071029465,0.025994511,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,pregabalin,DB00230
,10269,DB00316,10020772,836,64638,468,36485,0.907604362,1.008293289,0.89865451,1.132342135,0.958771936,DB0031610020772_,0.042102046,0.008259089,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,10271,DB00425,10020772,168,12527,71,7413,0.018263556,1.400202581,1.05318441,1.877846348,0.057502254,DB0042510020772_,2.855931129,0.336616927,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,zolpidem,DB00425
,10273,DB01068,10020772,152,13611,54,6786,0.037050818,1.403352946,1.020930995,1.954429223,0.099701142,DB0106810020772_,2.305578146,0.338864335,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,clonazepam,DB01068
,10274,DB01175,10020772,108,10616,60,4832,0.241466194,0.819322455,0.590983706,1.145091744,0.399575683,DB0117510020772_,0.917352089,-0.199277554,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,escitalopram,DB01175
,10275,DB01238,10020772,44,5206,25,3477,0.540420577,1.175419912,0.702273913,2.008192503,0.695972984,DB0123810020772_,0.362444435,0.161625456,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,aripiprazole,DB01238
,10277,DB13867,10020772,67,4483,32,2522,0.526985799,1.177885225,0.759676309,1.860709964,0.684700245,DB1386710020772_,0.378774135,0.163720649,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,fluticasone,DB13867
,10279,DB00316,10021015,271,65203,135,36818,0.254637147,1.133535037,0.918291533,1.404594294,0.415348748,DB0031610021015_,0.878636754,0.125341101,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,10281,DB00425,10021015,77,12618,15,7469,1.8061113302605e-05,3.038436358,1.731190824,5.693463349,0.000182507,DB0042510021015_,8.608724356,1.111343027,female,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,zolpidem,DB00425
,10282,DB00455,10021015,38,9363,18,5100,0.676316326,1.149891926,0.639608367,2.142794405,0.80384645,DB0045510021015_,0.21834701,0.139667961,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,loratadine,DB00455
,10284,DB00999,10021015,163,21267,97,12142,0.746599493,0.959423203,0.740870453,1.247943243,0.855579246,DB0099910021015_,0.155976559,-0.041423005,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,10285,DB01068,10021015,40,13723,18,6822,0.781588331,1.104705748,0.618350694,2.048830571,0.881104369,DB0106810021015_,0.126579193,0.099579008,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,clonazepam,DB01068
,10286,DB01175,10021015,43,10681,18,4874,0.890087066,1.090100326,0.614875947,2.010371192,0.954444894,DB0117510021015_,0.046625371,0.086269735,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,escitalopram,DB01175
,10290,DB00230,10048294,76,19598,44,8607,0.163934976,0.75856603,0.516114886,1.127082711,0.302697375,DB0023010048294_,1.195021735,-0.276325431,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,10291,DB00316,10048294,290,65184,273,36680,1.77544156351288e-09,0.597729189,0.504671648,0.708166774,4.687843445197e-08,DB0031610048294_,16.87570809,-0.514617489,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,10293,DB00425,10048294,84,12611,47,7437,0.856068139,1.053975276,0.728033907,1.541835674,0.930627756,DB0042510048294_,0.071895914,0.052568993,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,10294,DB00455,10048294,46,9355,21,5097,0.60838227,1.193423165,0.697051038,2.107991732,0.751034851,DB0045510048294_,0.286303222,0.176825787,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,loratadine,DB00455
,10296,DB00999,10048294,77,21353,60,12179,0.075078871,0.731997611,0.515118114,1.044428337,0.169970986,DB0099910048294_,1.772127529,-0.311978028,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,10297,DB01050,10048294,72,18036,67,9304,0.000613457,0.554340947,0.391514158,0.785862301,0.003666373,DB0105010048294_,5.608552308,-0.589975353,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,10298,DB01068,10048294,93,13670,71,6769,0.007533122,0.64860438,0.47044908,0.897528207,0.028389642,DB0106810048294_,3.561730917,-0.432932332,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,10299,DB01175,10048294,56,10668,34,4858,0.209555415,0.750030604,0.480560072,1.186329756,0.360664589,DB0117510048294_,1.01980687,-0.287641268,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,10300,DB01238,10048294,39,5211,21,3481,0.508913502,1.240547531,0.710652547,2.223812149,0.669437756,DB0123810048294_,0.401317089,0.215552839,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,10322,DB00108,10020100,62,10132,10,3285,0.038530105,2.00996557,1.021625969,4.402562379,0.102709174,DB0010810020100_,2.275853837,0.698117592,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,natalizumab,DB00108
,10331,DB00181,10016173,624,9232,266,5605,1.9942684562738e-06,1.424207128,1.226934148,1.656680341,2.64077311703561e-05,DB0018110016173_,10.54185374,0.353615258,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,10332,DB00295,10016173,265,14398,177,9425,0.844438941,0.980051167,0.805702328,1.194436045,0.921381385,DB0029510016173_,0.08188123,-0.020150498,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,10333,DB00295,10047700,752,13911,340,9262,3.58716220880018e-09,1.472577893,1.290188487,1.683329048,8.89934484741036e-08,DB0029510047700_,16.23470308,0.387014533,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,10334,DB00181,10048031,38,9818,41,5830,0.00986035,0.550403949,0.344055916,0.878475343,0.03516729,DB0018110048031_,3.347638897,-0.597102817,NA,10048031,Wound dehiscence,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,10341,DB00181,10063782,39,9817,26,5845,0.70031164,0.893102691,0.529471167,1.529697386,0.819879108,DB0018110063782_,0.198598379,-0.113053709,NA,10063782,Implant site pain,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,10344,DB00181,10020642,98,9758,99,5772,0.000201443,0.585587116,0.437431232,0.783771769,0.00144967,DB0018110020642_,6.536419081,-0.535140318,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,baclofen,DB00181
,10345,DB00181,10022998,49,9807,51,5820,0.006687351,0.57022776,0.376731411,0.862240013,0.025830568,DB0018110022998_,3.656196691,-0.56171942,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,10346,DB00181,10044565,176,9680,114,5757,0.500435107,0.918188116,0.719592413,1.175345006,0.661999838,DB0018110044565_,0.412489967,-0.08535299,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,10347,DB09072,10042458,245,6226,111,2424,0.206586963,0.859373428,0.680421447,1.0908251,0.357163701,DB0907210042458_,1.029561056,-0.151551727,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,10348,DB09072,10061920,54,6417,22,2513,0.898202231,0.961241703,0.574270307,1.66124354,0.956353692,DB0907210061920_,0.044627464,-0.03952939,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,10349,DB09072,10040979,240,6231,146,2389,2.89519889584698e-05,0.630290908,0.508088031,0.783968682,0.000274979,DB0907210040979_,8.198817604,-0.461573808,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium oxybate,DB09072
,10350,DB00999,10005724,178,21252,53,12186,1.36201865219827e-05,1.9257389,1.40864312,2.67141156,0.000142377,DB0099910005724_,8.857033105,0.655309738,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,10353,DB00999,10005750,335,21095,147,12092,0.007504691,1.306299435,1.071435673,1.598958809,0.028303436,DB0099910005750_,3.564772057,0.267198281,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,10355,DB09072,10005750,174,6297,68,2467,1,1.00248005,0.75011725,1.352532791,1,DB0907210005750_,0,0.00247698,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,sodium oxybate,DB09072
,10356,DB00999,10047895,506,20924,275,11964,0.522374398,1.052084409,0.904982258,1.225133533,0.680961055,DB0099910047895_,0.384250162,0.050773348,NA,10047895,Weight decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,10357,DB01255,10047895,50,2083,39,1539,0.828615827,0.947264311,0.6073078,1.486915339,0.909933448,DB0125510047895_,0.094383816,-0.054177122,NA,10047895,Weight decreased,10022891,Investigations,Inv,lisdexamfetamine,DB01255
,10358,DB09072,10047895,265,6206,83,2452,0.077709077,1.261413155,0.977603969,1.641669548,0.174475365,DB0907210047895_,1.745971722,0.232232644,NA,10047895,Weight decreased,10022891,Investigations,Inv,sodium oxybate,DB09072
,10359,DB00999,10062355,130,21300,66,12173,0.457154064,1.125700727,0.830051653,1.539092103,0.624450168,DB0099910062355_,0.470883748,0.11840571,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,10360,DB01255,10062355,46,2087,37,1541,0.736765851,0.918008434,0.579376953,1.463354265,0.848079282,DB0125510062355_,0.164781155,-0.085548701,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,lisdexamfetamine,DB01255
,10361,DB09072,10062355,275,6196,100,2435,0.557578456,1.080727315,0.852215541,1.379403906,0.710660414,DB0907210062355_,0.341560581,0.077634254,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,10364,DB00331,10003549,596,24350,533,20219,0.226076813,0.928504731,0.823452233,1.04713579,0.38097378,DB0033110003549_,0.965024725,-0.074179803,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,10365,DB00335,10003549,283,8183,175,5290,0.661755109,1.045423209,0.859919495,1.27368367,0.793767907,DB0033510003549_,0.230964169,0.044421788,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,10366,DB00641,10003549,452,13672,425,12050,0.353032308,0.937382278,0.817346302,1.075113012,0.522786153,DB0064110003549_,0.648582785,-0.064664099,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,10368,DB01067,10003549,130,4231,141,4682,0.90177318,1.020265969,0.79464152,1.309091134,0.957082614,DB0106710003549_,0.043865565,0.020063347,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,10370,DB00331,10016173,636,24310,433,20319,0.001096241,1.227677434,1.083254169,1.392404516,0.005938112,DB0033110016173_,5.126364012,0.205124119,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,10371,DB00335,10016173,256,8210,138,5327,0.084337814,1.20361045,0.971878226,1.495735068,0.185624405,DB0033510016173_,1.684029977,0.185325748,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,atenolol,DB00335
,10373,DB01067,10016173,128,4233,115,4708,0.103887827,1.237909288,0.951338754,1.612309584,0.216850628,DB0106710016173_,1.528546511,0.213423899,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,glipizide,DB01067
,10375,DB00115,10016288,81,18344,49,10423,0.715699337,0.939266599,0.650232549,1.369114587,0.831734356,DB0011510016288_,0.184242173,-0.062655922,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,cyanocobalamin,DB00115
,10376,DB00331,10016288,41,24905,69,20683,0.000345002,0.493484585,0.326684429,0.7370667,0.002267946,DB0033110016288_,6.088880679,-0.706263657,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,metformin,DB00331
,10378,DB00641,10016288,26,14098,47,12428,0.003128444,0.487679791,0.28973764,0.804302196,0.014000776,DB0064110016288_,4.268642499,-0.718096255,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,simvastatin,DB00641
,10382,DB00115,10025482,615,17810,206,10266,5.85155183566988e-12,1.720827347,1.464417288,2.028702697,2.33042484849368e-10,DB0011510025482_,22.17980034,0.542805191,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,10383,DB00331,10025482,726,24220,338,20414,5.51168424729879e-20,1.810369017,1.586770405,2.068705749,5.68135766432347e-18,DB0033110025482_,39.70934144,0.593530701,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,10384,DB00335,10025482,259,8207,114,5351,0.000465625,1.481267329,1.180510705,1.868106933,0.002911265,DB0033510025482_,5.83916769,0.392898025,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,10386,DB01067,10025482,117,4244,97,4726,0.037528568,1.343123629,1.013973393,1.782469527,0.100630382,DB0106710025482_,2.296301062,0.294997967,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,10388,DB00335,10033371,330,8136,136,5329,5.33161302752682e-06,1.589262199,1.293579885,1.961171216,6.25771147258507e-05,DB0033510033371_,9.679110926,0.463269883,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,10389,DB00641,10033371,505,13619,281,12194,1.4877116425736e-10,1.609076361,1.384991359,1.872342792,4.71706882087419e-09,DB0064110033371_,19.17207824,0.475660325,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,10391,DB01067,10033371,173,4188,104,4719,4.58529347321951e-07,1.874225797,1.455743678,2.422799106,7.17407374664136e-06,DB0106710033371_,11.8450369,0.628195666,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,10393,DB00115,10033661,67,18358,73,10399,0.000134164,0.519895112,0.367171829,0.735156467,0.001024254,DB0011510033661_,6.883790764,-0.654128195,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,cyanocobalamin,DB00115
,10394,DB00331,10033661,62,24884,60,20692,0.413705646,0.859260776,0.592402185,1.24703862,0.583050936,DB0033110033661_,0.539480727,-0.151682822,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,metformin,DB00331
,10396,DB00641,10033661,47,14077,59,12416,0.0789988,0.702629761,0.468155352,1.049375349,0.176676887,DB0064110033661_,1.73343271,-0.352925182,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,simvastatin,DB00641
,10398,DB01067,10033661,34,4327,32,4791,0.537839336,1.176412977,0.702997718,1.972877219,0.693930885,DB0106710033661_,0.365382913,0.162469958,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,glipizide,DB01067
,10400,DB00115,10039101,111,18314,43,10429,0.03527942,1.469969868,1.024142036,2.143815411,0.096006889,DB0011510039101_,2.343335334,0.385241903,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,10401,DB00331,10039101,115,24831,76,20676,0.126305329,1.259951872,0.934277605,1.707365386,0.250513908,DB0033110039101_,1.38424084,0.231073524,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,10402,DB00335,10039101,49,8417,25,5440,0.403518331,1.266734847,0.76633049,2.143068564,0.573230251,DB0033510039101_,0.556467808,0.236442603,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atenolol,DB00335
,10403,DB00641,10039101,82,14042,51,12424,0.054990707,1.422555953,0.99001461,2.061095682,0.134321227,DB0064110039101_,2.007521131,0.35245522,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,10407,DB00028,10003239,207,13251,62,5553,0.021795077,1.399159835,1.046763715,1.892894807,0.06615666,DB0002810003239_,2.715729716,0.335871939,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,human immunoglobulin g,DB00028
,10410,DB00264,10010264,468,29139,269,24623,4.67444650756988e-07,1.470130258,1.261426784,1.7161282,7.30269399414409e-06,DB0026410010264_,11.82726724,0.385351008,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,10412,DB00641,10010264,251,13873,130,12345,4.62252246249899e-07,1.718069975,1.382647942,2.143124268,7.22932493339722e-06,DB0064110010264_,11.8373649,0.541201553,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,10413,DB00722,10010264,422,24981,275,25757,2.95927365656103e-09,1.582188997,1.354586135,1.85050155,7.48287715850955e-08,DB0072210010264_,16.40806338,0.458809329,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,10414,DB00727,10010264,78,3765,58,4115,0.030212164,1.46976312,1.029732435,2.108066099,0.085151911,DB0072710010264_,2.463318433,0.385101245,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,10415,DB00745,10010264,76,2501,41,1042,0.216315423,0.772331324,0.517664034,1.166726218,0.369007425,DB0074510010264_,0.996938514,-0.258341645,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,modafinil,DB00745
,10416,DB00758,10010264,138,8162,122,9952,0.011923391,1.379181387,1.07117305,1.77749222,0.040949412,DB0075810010264_,3.195417835,0.321490125,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,10418,DB00927,10010264,137,7360,62,4954,0.010543068,1.487282835,1.091483395,2.046085363,0.037130641,DB0092710010264_,3.293312746,0.396950855,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,10419,DB01202,10010264,114,6600,103,5615,0.68046767,0.941646258,0.713214416,1.244423749,0.806696585,DB0120210010264_,0.21480766,-0.060125598,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,10420,DB01233,10010264,58,3363,22,1704,0.283468268,1.335769399,0.801902387,2.300330377,0.44782807,DB0123310010264_,0.803345893,0.289507455,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,10421,DB01306,10010264,83,4125,46,3820,0.005714014,1.670824465,1.148335981,2.457388515,0.022768568,DB0130610010264_,3.782374291,0.513317196,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,10427,DB00641,10012174,171,13953,194,12281,0.017398065,0.775830254,0.626964465,0.959291124,0.055401069,DB0064110012174_,2.893156384,-0.253821528,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,simvastatin,DB00641
,10428,DB00722,10012174,369,25034,417,25615,0.172008049,0.905439426,0.784058028,1.045285095,0.313473728,DB0072210012174_,1.160039726,-0.0993349,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,10429,DB00727,10012174,40,3803,59,4114,0.156148744,0.733438543,0.477084875,1.117316086,0.292313207,DB0072710012174_,1.229929424,-0.310011471,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,nitroglycerin,DB00727
,10431,DB00758,10012174,114,8186,120,9954,0.290330812,1.155168395,0.884500187,1.508010277,0.455561914,DB0075810012174_,0.786223646,0.14424613,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,clopidogrel,DB00758
,10433,DB00927,10012174,139,7358,67,4949,0.026234447,1.395359894,1.032758436,1.901024519,0.076280137,DB0092710012174_,2.573342706,0.33315237,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,famotidine,DB00927
,10434,DB01104,10012174,176,15287,83,7203,1,0.99911121,0.764136732,1.315315015,1,DB0110410012174_,0,-0.000889185,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,sertraline,DB01104
,10435,DB01233,10012174,82,3339,62,1664,0.015635892,0.659150229,0.46556546,0.937251132,0.050937402,DB0123310012174_,2.977157819,-0.416803806,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,metoclopramide,DB01233
,10436,DB01306,10012174,76,4132,62,3804,0.493123785,1.128484108,0.793831621,1.609542291,0.655909657,DB0130610012174_,0.421732218,0.120875235,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,insulin aspart,DB01306
,10452,DB01233,10021518,51,3370,14,1712,0.046495733,1.850417563,1.005364499,3.630664337,0.118487599,DB0123310021518_,2.132946976,0.615411323,NA,10021518,Impaired gastric emptying,10017947,Gastrointestinal disorders,Gastr,metoclopramide,DB01233
,10458,DB00264,10028813,1703,27904,874,24018,2.26748317193306e-35,1.677134336,1.542018356,1.825085129,7.0533485413326e-33,DB0026410028813_,74.03180559,0.517086584,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,10460,DB00641,10028813,834,13290,403,12072,1.40268512895157e-25,1.87976332,1.662660626,2.127992961,2.24814503746903e-23,DB0064110028813_,52.14935169,0.631145875,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,10461,DB00727,10028813,258,3585,161,4012,1.14388503141134e-08,1.79320152,1.459241346,2.208780214,2.54159070588732e-07,DB0072710028813_,15.1853055,0.584002581,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,nitroglycerin,DB00727
,10462,DB00745,10028813,180,2397,57,1026,0.055737853,1.351614849,0.988495911,1.871105226,0.13559808,DB0074510028813_,1.998060064,0.301300062,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,modafinil,DB00745
,10464,DB00927,10028813,586,6911,198,4818,2.58380173607852e-19,2.063149282,1.74553788,2.446489751,2.52472968895256e-17,DB0092710028813_,38.21781258,0.724233593,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,10465,DB01233,10028813,335,3086,150,1576,0.206839823,1.140545251,0.928672664,1.405509867,0.357500506,DB0123310028813_,1.028618502,0.131506439,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,metoclopramide,DB01233
,10466,DB01306,10028813,276,3932,146,3720,1.75402856698548e-08,1.788350392,1.450401981,2.212259217,3.72111710114717e-07,DB0130610028813_,14.80407173,0.581293626,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,insulin aspart,DB01306
,10467,DB09401,10028813,52,708,24,736,0.001338705,2.251207223,1.346242651,3.862408402,0.006999079,DB0940110028813_,4.961976758,0.811466616,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,isosorbide,DB09401
,10471,DB00264,10061428,562,29045,435,24457,0.199356359,1.087905172,0.957021178,1.237251339,0.348282336,DB0026410061428_,1.054741818,0.084253987,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,10473,DB00695,10061428,603,27446,424,20104,0.544160346,1.041734035,0.917248672,1.183923744,0.699241384,DB0069510061428_,0.357759268,0.040886666,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,10474,DB00727,10061428,61,3782,68,4105,0.929289093,0.973670729,0.675621136,1.400570432,0.970841169,DB0072710061428_,0.029592399,-0.026682093,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,nitroglycerin,DB00727
,10476,DB00758,10061428,122,8178,159,9915,0.586828964,0.930252506,0.727303088,1.187501672,0.733958477,DB0075810061428_,0.309302823,-0.072299218,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,clopidogrel,DB00758
,10478,DB00927,10061428,169,7328,92,4924,0.110839559,1.234301725,0.949312672,1.613273573,0.227344347,DB0092710061428_,1.481289466,0.210505405,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,famotidine,DB00927
,10479,DB01104,10061428,227,15236,129,7157,0.096691636,0.826625322,0.661794134,1.036120761,0.205792684,DB0110410061428_,1.580886006,-0.190403743,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,sertraline,DB01104
,10480,DB01202,10061428,111,6603,68,5650,0.034202052,1.39671828,1.021372837,1.921880001,0.093812057,DB0120210061428_,2.366461894,0.334125399,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,levetiracetam,DB01202
,10481,DB01233,10061428,73,3348,64,1662,0.001262822,0.566271779,0.397051562,0.809302142,0.006664645,DB0123310061428_,5.010938623,-0.568681142,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,metoclopramide,DB01233
,10482,DB01306,10061428,72,4136,76,3790,0.407193328,0.868131871,0.618070118,1.218346142,0.576751739,DB0130610061428_,0.550343367,-0.141411651,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,insulin aspart,DB01306
,10487,DB00327,10043414,34,6104,25,4237,0.894558478,0.944040594,0.546005903,1.653160382,0.955948677,DB0032710043414_,0.045051053,-0.057586112,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,10489,DB09072,10020772,201,6270,82,2453,0.737530991,0.9589884,0.734831919,1.260955123,0.848755592,DB0907210020772_,0.163984011,-0.0418763,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,sodium oxybate,DB09072
,10491,DB09072,10042464,135,6336,48,2487,0.618469921,1.103945819,0.785852946,1.573725381,0.759329341,DB0907210042464_,0.275319681,0.09889087,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,10492,DB09072,10053762,328,6143,154,2381,0.060838493,0.825571982,0.675522629,1.012345315,0.144967798,DB0907210053762_,1.931243641,-0.191678821,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium oxybate,DB09072
,10493,DB00381,10012735,1945,27415,1131,21756,3.35444774908574e-16,1.364722858,1.264840576,1.472922617,2.36702440495889e-14,DB0038110012735_,31.37455766,0.310951373,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,10494,DB00571,10012735,215,4908,87,2522,0.071636094,1.269868081,0.980528523,1.656176577,0.164127673,DB0057110012735_,1.807110661,0.238913022,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,propranolol,DB00571
,10495,DB00669,10012735,160,6217,26,1071,0.916349337,1.060126079,0.693315364,1.681049939,0.962639876,DB0066910012735_,0.038075898,0.058387843,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sumatriptan,DB00669
,10496,DB00697,10012735,315,5781,61,1745,0.001313138,1.558603949,1.17485694,2.096612038,0.006888698,DB0069710012735_,4.977873227,0.443790516,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,tizanidine,DB00697
,10497,DB00999,10012735,1425,20005,581,11658,6.32210835379665e-13,1.429287758,1.293352665,1.581086307,2.90518563076128e-11,DB0099910012735_,24.26193873,0.357176249,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,10498,DB01068,10012735,563,13200,226,6614,0.005494638,1.248251886,1.064638986,1.467218263,0.022058276,DB0106810012735_,3.814067425,0.221744081,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,10499,DB01076,10012735,1489,24258,1231,24352,9.16211340419548e-07,1.21426596,1.122804537,1.313294472,1.32704788988609e-05,DB0107610012735_,11.22996862,0.194139746,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,10500,DB09072,10012735,114,6357,36,2499,0.272956154,1.244802484,0.846359201,1.87023542,0.435947032,DB0907210012735_,0.830234528,0.21897687,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sodium oxybate,DB09072
,10501,DB00338,10028813,2447,31227,980,21292,3.36553271115433e-45,1.702505487,1.576974495,1.839076034,1.60841867841257e-42,DB0033810028813_,96.2333224,0.532100982,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,10502,DB00381,10028813,1830,27530,808,22079,7.04225659347825e-46,1.816380629,1.6679366,1.979357154,3.49256065206747e-43,DB0038110028813_,97.76052382,0.596845856,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,10503,DB00571,10028813,268,4855,94,2515,0.001164018,1.476845527,1.157290029,1.89792135,0.006246673,DB0057110028813_,5.075706205,0.389908412,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,propranolol,DB00571
,10504,DB00669,10028813,378,5999,40,1057,0.001716169,1.664942831,1.191063669,2.383673017,0.00857269,DB0066910028813_,4.75917367,0.509790787,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sumatriptan,DB00669
,10505,DB00697,10028813,457,5639,75,1731,2.49039562001742e-07,1.870386468,1.452954496,2.435264597,4.13780334210859e-06,DB0069710028813_,12.3953455,0.626145077,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,tizanidine,DB00697
,10506,DB01068,10028813,819,12944,239,6601,9.76775976732408e-15,1.747496287,1.506386135,2.03324742,5.76308788965462e-13,DB0106810028813_,28.18213279,0.558184071,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,10507,DB01076,10028813,1506,24241,925,24658,5.81801122010687e-33,1.656086079,1.521892779,1.802819164,1.56847615303086e-30,DB0107610028813_,68.62744824,0.504457035,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,10508,DB09072,10028813,514,5957,98,2437,5.0554362737826e-13,2.145524902,1.716058159,2.704887091,2.35189632666152e-11,DB0907210028813_,24.47321407,0.763384232,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sodium oxybate,DB09072
,10509,DB00338,10047700,1271,32403,543,21729,6.72611738415963e-19,1.569626257,1.416339653,1.741258522,6.2804971738059e-17,DB0033810047700_,37.30649744,0.450837538,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,10510,DB00381,10047700,955,28405,422,22465,3.98519952298632e-24,1.789768626,1.592141401,2.014478936,5.77140327612647e-22,DB0038110047700_,48.90395679,0.582086352,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,10511,DB00571,10047700,155,4968,61,2548,0.09300673,1.303208245,0.959067051,1.789605604,0.200104926,DB0057110047700_,1.608913418,0.264829105,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,propranolol,DB00571
,10512,DB00669,10047700,179,6198,21,1076,0.104385933,1.479699076,0.933844849,2.461017696,0.217587157,DB0066910047700_,1.525155788,0.39183874,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sumatriptan,DB00669
,10513,DB00697,10047700,237,5859,27,1779,9.19591689602806e-08,2.665133554,1.778305412,4.143869717,1.67682744094414e-06,DB0069710047700_,13.29860698,0.980254171,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,tizanidine,DB00697
,10514,DB00999,10047700,632,20798,186,12053,2.89259589007408e-17,1.969106068,1.666824827,2.335172502,2.31099948238897e-15,DB0099910047700_,33.70109629,0.677579667,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,10515,DB01068,10047700,395,13368,131,6709,3.50279194300705e-05,1.513244066,1.236022441,1.862415481,0.000325052,DB0106810047700_,8.031526396,0.414255735,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,10516,DB01076,10047700,803,24944,442,25141,6.39136846934058e-25,1.831056209,1.626201083,2.063886763,9.71081619749231e-23,DB0107610047700_,50.6862168,0.604892964,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,10517,DB09072,10047700,244,6227,69,2466,0.014931514,1.400415533,1.063155288,1.864682305,0.049145044,DB0907210047700_,3.012979273,0.336769002,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sodium oxybate,DB09072
,10518,DB00381,10047895,601,28759,486,22401,0.557298365,0.96321711,0.852139797,1.08923719,0.71044122,DB0038110047895_,0.341869065,-0.03747644,NA,10047895,Weight decreased,10022891,Investigations,Inv,amlodipine,DB00381
,10519,DB00555,10047895,90,6957,42,3444,0.780970599,1.060795344,0.725853541,1.572466265,0.880700697,DB0055510047895_,0.127037442,0.059018951,NA,10047895,Weight decreased,10022891,Investigations,Inv,lamotrigine,DB00555
,10520,DB00571,10047895,78,5045,42,2567,0.770934505,0.944960205,0.639197828,1.414251006,0.874560905,DB0057110047895_,0.134033341,-0.056612463,NA,10047895,Weight decreased,10022891,Investigations,Inv,propranolol,DB00571
,10521,DB00669,10047895,70,6307,11,1086,0.875502149,1.095767469,0.574063163,2.302686152,0.94649511,DB0066910047895_,0.054989475,0.091455003,NA,10047895,Weight decreased,10022891,Investigations,Inv,sumatriptan,DB00669
,10522,DB00697,10047895,131,5965,31,1775,0.298118908,1.257428295,0.841304942,1.932122902,0.464045825,DB0069710047895_,0.767771972,0.229068599,NA,10047895,Weight decreased,10022891,Investigations,Inv,tizanidine,DB00697
,10523,DB01068,10047895,283,13480,136,6704,0.793323461,1.034883461,0.838679501,1.281987951,0.887941952,DB0106810047895_,0.118848907,0.034288822,NA,10047895,Weight decreased,10022891,Investigations,Inv,clonazepam,DB01068
,10524,DB01076,10047895,544,25203,584,24999,0.195462673,0.923990367,0.819507873,1.041597963,0.343626818,DB0107610047895_,1.068199043,-0.079053633,NA,10047895,Weight decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,10525,DB00381,10053762,689,28671,455,22432,0.005560833,1.184762762,1.049544303,1.338344736,0.022272988,DB0038110053762_,3.804380632,0.169542554,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,10526,DB00555,10053762,262,6785,123,3363,0.659066453,1.055777308,0.845419727,1.324243263,0.791749239,DB0055510053762_,0.233510554,0.05427728,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lamotrigine,DB00555
,10527,DB00571,10053762,366,4757,146,2463,0.010300329,1.29791534,1.061577727,1.593233701,0.036429513,DB0057110053762_,3.312376031,0.260759393,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,propranolol,DB00571
,10528,DB00669,10053762,141,6236,17,1080,0.173614628,1.43637696,0.861437886,2.5460311,0.315624754,DB0066910053762_,1.153201258,0.362123943,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sumatriptan,DB00669
,10529,DB00697,10053762,177,5919,50,1756,0.810167068,1.050245022,0.75958105,1.474716306,0.897832552,DB0069710053762_,0.107771696,0.049023492,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tizanidine,DB00697
,10530,DB00999,10053762,559,20871,252,11987,0.001475648,1.274029676,1.094080405,1.486791014,0.007586037,DB0099910053762_,4.881446002,0.242184851,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,10531,DB01068,10053762,473,13290,250,6590,0.421659593,0.938173946,0.800798547,1.101193805,0.590716716,DB0106810053762_,0.526418706,-0.063819904,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,10534,DB00181,10021519,38,9818,24,5847,0.895448294,0.942940456,0.55050851,1.645057924,0.95615204,DB0018110021519_,0.044838341,-0.058752142,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,10536,DB01062,10037660,80,4406,41,1704,0.152614579,0.754655208,0.509351649,1.132998154,0.287608501,DB0106210037660_,1.246155097,-0.281494312,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,10540,DB00181,10020852,67,9789,105,5766,2.93193295605979e-10,0.375879532,0.271946803,0.516491885,8.89905978637777e-09,DB0018110020852_,18.53732021,-0.97848658,NA,10020852,Hypertonia,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,10542,DB09072,10002855,456,6015,124,2411,0.000157672,1.473970757,1.198860253,1.822768491,0.001177553,DB0907210002855_,6.74431642,0.387959954,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,10545,DB00472,10013754,75,10684,37,4275,0.295422867,0.811057891,0.539167655,1.239278261,0.461307554,DB0047210013754_,0.773690313,-0.209415845,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,10547,DB00472,10016256,622,10137,196,4116,0.002478576,1.288487075,1.090994487,1.527037604,0.011589321,DB0047210016256_,4.457671228,0.25346872,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,10548,DB09072,10016256,314,6157,124,2411,0.956568089,0.991599698,0.798453678,1.237466041,0.994242249,DB0907210016256_,0.005774391,-0.008435783,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,10549,DB00472,10022000,88,10671,29,4283,0.411536002,1.217916999,0.791119832,1.925517067,0.580977701,DB0047210022000_,0.543042904,0.197142022,NA,10022000,Influenza,10021881,Infections and infestations,Infec,fluoxetine,DB00472
,10550,DB09072,10022000,84,6387,27,2508,0.397225272,1.22160954,0.78137142,1.966084569,0.566863905,DB0907210022000_,0.56763603,0.200169284,NA,10022000,Influenza,10021881,Infections and infestations,Infec,sodium oxybate,DB09072
,10551,DB00472,10022437,213,10546,87,4225,0.897344136,0.980843339,0.75879412,1.276957716,0.956338178,DB0047210022437_,0.044643686,-0.019342527,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,10552,DB00472,10022523,130,10629,86,4226,0.000351775,0.601032757,0.453094213,0.800659303,0.002302963,DB0047210022523_,6.073558821,-0.509105841,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,10553,DB00472,10033775,133,10626,22,4290,3.2970956080041e-05,2.440563131,1.544277667,4.031878034,0.000308225,DB0047210033775_,8.084679914,0.892228804,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,10554,DB09072,10033775,104,6367,21,2514,0.003586798,1.95531602,1.211666009,3.298965113,0.015620739,DB0907210033775_,4.159155796,0.670551827,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,10557,DB00472,10061422,24,10735,42,4270,3.5776133711076e-09,0.227321368,0.131500659,0.384688483,8.87984584131854e-08,DB0047210061422_,16.23689655,-1.481390546,male,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,10560,DB00722,10005724,121,25282,57,25975,5.71269328763094e-07,2.180951084,1.578354183,3.044651242,8.71998507929032e-06,DB0072210005724_,11.64989303,0.779761059,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,lisinopril,DB00722
,10563,DB09072,10019303,54,6417,16,2519,0.353344793,1.324790543,0.745288,2.484697599,0.523116274,DB0907210019303_,0.647951519,0.281254366,NA,10019303,Heart rate increased,10022891,Investigations,Inv,sodium oxybate,DB09072
,10565,DB00722,10020642,204,25199,153,25879,0.003449012,1.369299279,1.104100486,1.701137221,0.015140497,DB0072210020642_,4.190382232,0.314299134,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,10566,DB09072,10020642,114,6357,34,2501,0.167665182,1.319059453,0.889629182,2.001791635,0.307756934,DB0907210020642_,1.178444983,0.276918947,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,sodium oxybate,DB09072
,10569,DB00722,10025256,43,25360,13,26019,4.01978136172379e-05,3.393878461,1.790663172,6.881461213,0.000366302,DB0072210025256_,7.912051092,1.221973356,female,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,lisinopril,DB00722
,10572,DB00722,10029366,53,25350,43,25989,0.262653666,1.263618389,0.828825934,1.936217659,0.42440841,DB0072210029366_,0.857059056,0.233979343,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,lisinopril,DB00722
,10575,DB00722,10040979,71,25332,44,25988,0.008766395,1.655395956,1.120345037,2.470059257,0.032043484,DB0072210040979_,3.440661435,0.504040229,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,10581,DB00181,10048294,163,9693,183,5688,2.81402541183413e-09,0.522690669,0.419490102,0.650849853,7.14999110198745e-08,DB0018110048294_,16.45356963,-0.648765446,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,10582,DB00297,10013754,63,1609,51,828,0.020359493,0.635787004,0.428160425,0.947992755,0.062673781,DB0029710013754_,2.769812087,-0.452891672,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,bupivacaine,DB00297
,10583,DB00327,10013754,125,6013,81,4181,0.667882823,1.073041569,0.802491192,1.441445485,0.798258458,DB0032710013754_,0.225322851,0.070497204,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,10584,DB00575,10013754,74,5170,69,3760,0.147208954,0.780002473,0.552614032,1.102074994,0.280035109,DB0057510013754_,1.272840296,-0.248458189,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,10585,DB00181,10057362,79,9777,84,5787,0.000229946,0.556713777,0.403476253,0.767461154,0.001619544,DB0018110057362_,6.425610586,-0.585704037,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,10589,DB00181,10008164,69,9787,51,5820,0.255876881,0.804571021,0.551279724,1.180937107,0.416634071,DB0018110008164_,0.875546969,-0.217446037,NA,10008164,Cerebrospinal fluid leakage,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,10590,DB00181,10058046,34,9822,18,5853,0.774610603,1.125614552,0.617455701,2.119044695,0.877160077,DB0018110058046_,0.131065775,0.118329155,NA,10058046,Post procedural complication,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,10592,DB00182,10012374,33,5161,22,2830,0.482008463,0.822546921,0.464367566,1.483950613,0.64644076,DB0018210012374_,0.436273718,-0.195349751,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,10596,DB00182,10020772,79,5115,36,2816,0.377939725,1.208061099,0.8024234,1.850207616,0.547894309,DB0018210020772_,0.601672877,0.189016677,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,amphetamine,DB00182
,10598,DB01255,10020772,32,2101,19,1559,0.478626239,1.249656374,0.684170021,2.342862014,0.643908829,DB0125510020772_,0.440198133,0.222868613,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,lisdexamfetamine,DB01255
,10600,DB01255,10022437,75,2058,46,1532,0.349984966,1.213652347,0.824395859,1.803252354,0.519605458,DB0125510022437_,0.654685491,0.193634282,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,lisdexamfetamine,DB01255
,10602,DB01255,10047899,51,2082,25,1553,0.100470074,1.521504029,0.920765074,2.574823259,0.211529571,DB0125510047899_,1.553390475,0.419699338,NA,10047899,Weight increased,10022891,Investigations,Inv,lisdexamfetamine,DB01255
,10603,DB09072,10047899,132,6339,42,2493,0.268387618,1.235978339,0.864423381,1.799238993,0.430865971,DB0907210047899_,0.841958208,0.211862834,NA,10047899,Weight increased,10022891,Investigations,Inv,sodium oxybate,DB09072
,10614,DB00471,10074903,59,14130,13,5452,0.065776102,1.75114176,0.948568414,3.483391652,0.153751049,DB0047110074903_,1.872420551,0.560268009,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,10615,DB01104,10074903,93,15370,53,7233,0.28560597,0.825779989,0.582391619,1.181405344,0.450217573,DB0110410074903_,0.798024317,-0.191426898,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,10616,DB09072,10074903,71,6400,43,2492,0.02729932,0.64295591,0.432854638,0.964923797,0.078662863,DB0907210074903_,2.542584119,-0.441679127,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium oxybate,DB09072
,10617,DB00588,10013911,69,16455,37,8431,0.837353837,0.955501283,0.631335523,1.466981748,0.916179808,DB0058810013911_,0.087542637,-0.045519172,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,10619,DB00588,10019211,1009,15515,256,8212,7.62017127250401e-28,2.086106168,1.812032641,2.408459399,1.46737144247449e-25,DB0058810019211_,57.18115466,0.735299251,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,10620,DB09104,10037660,35,1015,24,848,0.508064142,1.218265942,0.698112884,2.15914226,0.668695696,DB0910410037660_,0.402426186,0.197428489,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,magnesium hydroxide,DB09104
,10623,DB00773,10014625,33,2290,27,2800,0.150614129,1.494284494,0.868450077,2.591900972,0.284771426,DB0077310014625_,1.256068433,0.401647493,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,etoposide,DB00773
,10624,DB00987,10014625,27,2077,36,2892,0.898083505,1.044315442,0.60768603,1.775034958,0.956338178,DB0098710014625_,0.044643686,0.043361591,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,cytarabine,DB00987
,10627,DB00181,10062355,76,9780,55,5816,0.27713197,0.821763295,0.572284481,1.186561296,0.440665064,DB0018110062355_,0.819470185,-0.196302888,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,10631,DB00295,10057362,42,14621,44,9558,0.035210622,0.624034813,0.39863324,0.975628067,0.095863194,DB0029510057362_,2.344833168,-0.471549122,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,10633,DB00338,10010305,352,33322,281,21991,0.019874901,0.826713329,0.704043393,0.971433253,0.061445752,DB0033810010305_,2.789600573,-0.190297284,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,10636,DB09072,10010305,126,6345,59,2476,0.248597456,0.833410832,0.604755294,1.159681254,0.40797018,DB0907210010305_,0.896561196,-0.182228562,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,10637,DB00338,10012378,601,33073,249,22023,1.42142358877941e-10,1.607214699,1.3828097,1.872471436,4.51778948380494e-09,DB0033810012378_,19.21524301,0.47450268,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,10638,DB06700,10012378,135,2090,37,581,1,1.014287386,0.691389499,1.519315454,1,DB0670010012378_,0,0.014186283,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,desvenlafaxine,DB06700
,10639,DB00338,10016322,580,33094,247,22025,2.51302942743702e-09,1.56276578,1.342878255,1.823016505,6.44124607510308e-08,DB0033810016322_,16.55795873,0.446457188,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,10641,DB09072,10016322,404,6067,138,2397,0.167675028,1.156608855,0.945287992,1.421853703,0.307764261,DB0907210016322_,1.178421174,0.145492323,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,10642,DB00338,10022437,602,33072,337,21935,0.0140841,1.184763572,1.03402037,1.359337544,0.046823163,DB0033810022437_,3.061377267,0.169543238,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,10644,DB06700,10022437,83,2142,18,600,0.390146664,1.291510156,0.761752013,2.304053246,0.560030859,DB0670010022437_,0.579763392,0.255812198,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,desvenlafaxine,DB06700
,10646,DB09072,10028334,101,6370,30,2505,0.203276516,1.323869251,0.870623431,2.067678652,0.352972632,DB0907210028334_,1.041364754,0.2805587,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium oxybate,DB09072
,10647,DB00338,10029410,104,33570,58,22214,0.334844482,1.186499624,0.852052624,1.666266855,0.503987586,DB0033810029410_,0.685203643,0.17100748,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,10650,DB00338,10061428,645,33029,451,21821,0.366235448,0.944857783,0.835414923,1.069343717,0.535832499,DB0033810061428_,0.623933669,-0.056720857,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,10653,DB09072,10061428,120,6351,25,2510,0.002766221,1.896908338,1.22150824,3.05506083,0.012649637,DB0907210061428_,4.370126742,0.64022537,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,sodium oxybate,DB09072
,10654,DB00338,10061822,202,33472,123,22149,0.495459893,1.086736232,0.863608072,1.37204494,0.65776874,DB0033810061822_,0.418901869,0.083178922,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,10658,DB00181,10003988,254,9602,138,5733,0.397727131,1.098950942,0.88730309,1.36566582,0.5674477,DB0018110003988_,0.566606692,0.094356036,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,10659,DB00297,10003988,22,1650,31,848,0.000359699,0.364886692,0.19995526,0.65542415,0.002346658,DB0029710003988_,6.054762944,-1.008168407,male,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bupivacaine,DB00297
,10660,DB00575,10003988,91,5153,58,3771,0.451949184,1.148134654,0.814686644,1.629249364,0.619524492,DB0057510003988_,0.478803044,0.138138586,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,clonidine,DB00575
,10661,DB00181,10001854,30,9826,20,5851,0.769901142,0.893200598,0.490217764,1.660988196,0.873962496,DB0018110001854_,0.134717815,-0.112944089,NA,10001854,Altered state of consciousness,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,10663,DB00181,10022004,93,9763,30,5841,0.002644143,1.854596971,1.21548132,2.903988847,0.01219535,DB0018110022004_,4.406700539,0.617667406,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,10664,DB00181,10028411,90,9766,45,5826,0.371831146,1.193147679,0.823937415,1.749276721,0.541493091,DB0018110028411_,0.613424972,0.176594923,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,10665,DB00413,10002855,58,2141,22,1185,0.155669134,1.45902107,0.874210505,2.516703277,0.291654241,DB0041310002855_,1.232186284,0.377765711,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,pramipexole,DB00413
,10666,DB01156,10002855,442,13180,139,6189,3.04530506207852e-05,1.493153362,1.228245679,1.824408185,0.000287573,DB0115610002855_,8.154035079,0.400890234,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,10667,DB00413,10012378,43,2156,21,1186,0.694555875,1.126359086,0.650342689,2.008275657,0.816129157,DB0041310012378_,0.203182656,0.118990383,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,pramipexole,DB00413
,10668,DB01156,10012378,544,13078,190,6138,0.000502371,1.343795884,1.133790252,1.59808216,0.003103002,DB0115610012378_,5.775385275,0.295498358,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,10669,DB01222,10012378,109,9165,43,5362,0.028068827,1.483000397,1.031151517,2.166519613,0.080382321,DB0122210012378_,2.520961021,0.394067331,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,budesonide,DB01222
,10670,DB00472,10013781,51,10708,16,4296,0.420200533,1.278768115,0.71650916,2.40537689,0.58912796,DB0047210013781_,0.529111869,0.245897205,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,10671,DB00722,10013781,144,25259,95,25937,0.000905642,1.556452904,1.19221481,2.039894476,0.005078898,DB0072210013781_,5.282660911,0.442409453,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,10672,DB01156,10013781,81,13541,32,6296,0.478824955,1.176903959,0.771821823,1.833954907,0.644060791,DB0115610013781_,0.439962161,0.162887227,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,10673,DB01222,10013781,45,9229,20,5385,0.367360983,1.312821905,0.758535727,2.349655852,0.537030863,DB0122210013781_,0.621699714,0.272178946,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,10674,DB09072,10013781,64,6407,17,2518,0.172398752,1.479560709,0.85404489,2.700231631,0.314011585,DB0907210013781_,1.158325399,0.391745226,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,sodium oxybate,DB09072
,10675,DB00413,10047899,48,2151,10,1197,0.003287313,2.670480796,1.327901339,5.942299996,0.014573038,DB0041310047899_,4.228582196,0.982258529,NA,10047899,Weight increased,10022891,Investigations,Inv,pramipexole,DB00413
,10676,DB01156,10047899,268,13354,65,6263,7.03133404855583e-07,1.933658732,1.467017106,2.580658001,1.04950945750307e-05,DB0115610047899_,11.46460259,0.659413924,NA,10047899,Weight increased,10022891,Investigations,Inv,bupropion,DB01156
,10677,DB00273,10002855,208,8273,28,2165,0.000580198,1.943863877,1.301901077,3.005337949,0.003495019,DB0027310002855_,5.656416578,0.664677681,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,10679,DB01104,10002855,438,15025,176,7110,0.072256118,1.177627229,0.984058517,1.414131941,0.165217004,DB0110410002855_,1.800495494,0.163501591,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,10680,DB00273,10010305,99,8382,40,2153,0.019712747,0.635759495,0.434728849,0.945322177,0.061102542,DB0027310010305_,2.795201812,-0.452934939,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,10682,DB01104,10010305,202,15261,134,7152,0.002176367,0.706460922,0.564007894,0.887248124,0.010430451,DB0110410010305_,4.563025754,-0.34748739,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,10686,DB00273,10012378,225,8256,33,2160,0.001329745,1.78370245,1.229664437,2.663037292,0.006964006,DB0027310012378_,4.967000419,0.578691232,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,10688,DB00273,10016256,433,8048,77,2116,0.001622944,1.478438009,1.151876458,1.918579254,0.008193427,DB0027310016256_,4.80442309,0.390986131,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,10690,DB00273,10027599,322,8159,40,2153,1.61254485024305e-06,2.124031701,1.520091321,3.03989903,2.19672150239122e-05,DB0027310027599_,10.72595944,0.753316028,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,10692,DB01104,10027599,136,15327,16,7270,7.33687124600237e-10,4.031124775,2.392711878,7.259176322,2.09051122711298e-08,DB0110410027599_,17.6832721,1.394045437,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,10693,DB09072,10027599,167,6304,32,2503,8.36591154892036e-05,2.071961116,1.40830132,3.135756886,0.000684934,DB0907210027599_,7.286188419,0.728495558,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,10694,DB00273,10062355,42,8439,8,2185,0.487656463,1.359271198,0.629225567,3.357180056,0.651422988,DB0027310062355_,0.428596096,0.306948672,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,10696,DB01104,10062355,100,15363,31,7255,0.039079968,1.523323954,1.008095725,2.361380791,0.10380123,DB0110410062355_,2.265277462,0.420894759,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,10697,DB00181,10001497,73,9783,88,5783,8.10182970920805e-06,0.490380415,0.353922823,0.677770432,9.04850622080024e-05,DB0018110001497_,9.310325779,-0.712573832,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,10698,DB00181,10049816,76,9780,71,5800,0.007687909,0.634856808,0.452502936,0.891555343,0.028857793,DB0018110049816_,3.545375192,-0.454355805,NA,10049816,Muscle tightness,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,10699,DB00182,10005750,72,5122,25,2827,0.053975098,1.58948135,0.993434858,2.621814265,0.132443564,DB0018210005750_,2.021598658,0.463407768,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,amphetamine,DB00182
,10700,DB00471,10005750,122,14067,39,5426,0.332172592,1.206607744,0.833868065,1.780415733,0.501027549,DB0047110005750_,0.691094192,0.187812905,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,montelukast,DB00471
,10701,DB00682,10005750,126,19333,79,16285,0.041429738,1.343469262,1.005288434,1.804575156,0.108599418,DB0068210005750_,2.220089234,0.29525527,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,warfarin,DB00682
,10702,DB01156,10005750,98,13524,42,6286,0.715852663,1.084535046,0.747247059,1.598294653,0.831856904,DB0115610005750_,0.184094843,0.081151366,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,bupropion,DB01156
,10703,DB00471,10012174,140,14049,59,5406,0.577853669,0.913084445,0.667805826,1.261850483,0.726758233,DB0047110012174_,0.319161411,-0.090926911,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,montelukast,DB00471
,10704,DB01156,10012174,116,13506,40,6288,0.119648883,1.350179413,0.933837835,1.988134411,0.240855514,DB0115610012174_,1.423558051,0.300237482,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,bupropion,DB01156
,10705,DB00182,10012735,109,5085,57,2795,0.806011683,1.051093324,0.753429734,1.479776153,0.895076663,DB0018210012735_,0.110845907,0.049830883,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,amphetamine,DB00182
,10706,DB00471,10012735,698,13491,236,5229,0.07864011,1.146338453,0.984092482,1.338988823,0.176054449,DB0047110012735_,1.736961963,0.136572909,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,10707,DB00682,10012735,1548,17911,809,15555,6.89591868348865e-31,1.661745999,1.521188876,1.816330913,1.64035495561538e-28,DB0068210012735_,63.97746995,0.507868856,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,10708,DB01156,10012735,506,13116,187,6141,0.006099434,1.266853551,1.066069863,1.510597985,0.023982591,DB0115610012735_,3.730427075,0.236536308,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,10709,DB00471,10053762,396,13793,164,5301,0.443930569,0.928011493,0.769440475,1.123294688,0.611920657,DB0047110053762_,0.49115265,-0.074711162,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,10710,DB00682,10053762,380,19079,289,16075,0.196292616,1.107818597,0.946779098,1.297407742,0.344567344,DB0068210053762_,1.065465726,0.102392854,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,10711,DB01156,10053762,352,13270,172,6156,0.600847174,0.949387136,0.786812921,1.148954395,0.74519395,DB0115610053762_,0.294110759,-0.051938623,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,10717,DB09072,10022035,72,6399,28,2507,1,1.007434649,0.641038897,1.623594294,1,DB0907210022035_,0,0.007407148,NA,10022035,Initial insomnia,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,10719,DB00331,10042458,84,24862,58,20694,0.311125661,1.205473407,0.852000274,1.715753209,0.478619846,DB0033110042458_,0.736848637,0.186872359,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,metformin,DB00331
,10720,DB00722,10042458,81,25322,75,25957,0.574713204,1.107079881,0.798213085,1.537174466,0.724373112,DB0072210042458_,0.322448671,0.101725811,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,10721,DB00736,10042458,50,10541,14,5539,0.034993873,1.876619642,1.020281761,3.679246849,0.095406488,DB0073610042458_,2.349608695,0.629472096,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,esomeprazole,DB00736
,10727,DB00472,10005750,80,10679,25,4287,0.329261378,1.284570386,0.809687219,2.104433075,0.497907912,DB0047210005750_,0.697340135,0.250424332,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,fluoxetine,DB00472
,10728,DB00472,10047513,81,10678,19,4293,0.034547795,1.713927241,1.028688138,2.996214076,0.094523658,DB0047210047513_,2.358905126,0.538787369,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,fluoxetine,DB00472
,10732,DB00108,10053762,68,10126,22,3273,1,0.99905533,0.60878773,1.700086147,1,DB0010810053762_,0,-0.000945117,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,natalizumab,DB00108
,10733,DB00060,10003246,76,9432,18,2447,0.798886243,1.095387898,0.647329452,1.950031033,0.891356522,DB0006010003246_,0.115010795,0.091108545,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,10734,DB00181,10008531,84,9772,55,5816,0.597735659,0.908993975,0.638332688,1.303447943,0.742836704,DB0018110008531_,0.297279038,-0.095416813,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,10735,DB00295,10008531,94,14569,56,9546,0.615726404,1.099859692,0.780923847,1.561474017,0.757025585,DB0029510008531_,0.278358228,0.095182619,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,10736,DB00295,10038687,29,14634,37,9565,0.00774801,0.512296843,0.303674061,0.856667973,0.029029182,DB0029510038687_,3.539453684,-0.66885105,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,10739,DB01202,10024264,68,6646,47,5671,0.301322354,1.2345329,0.837280626,1.833776648,0.467616713,DB0120210024264_,0.760106307,0.21069268,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,10740,DB01202,10033295,108,6606,100,5618,0.574824057,0.918480796,0.691506387,1.220899233,0.724455808,DB0120210033295_,0.322334516,-0.085034283,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,levetiracetam,DB01202
,10744,DB00555,10012378,220,6827,83,3403,0.035027926,1.321215305,1.018235543,1.727759961,0.095459724,DB0055510012378_,2.349050863,0.278551999,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,10745,DB00555,10042458,141,6906,64,3422,0.600248221,1.091661223,0.80439347,1.495173917,0.744697071,DB0055510042458_,0.29477776,0.087700594,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,10750,DB00334,10013709,163,2686,185,2627,0.184449355,0.861751099,0.688922239,1.077168941,0.329465618,DB0033410013709_,1.110283275,-0.148788798,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,olanzapine,DB00334
,10751,DB00334,10016322,42,2807,27,2785,0.089693769,1.543238626,0.926566026,2.610794826,0.19473038,DB0033410016322_,1.636139344,0.433883212,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,olanzapine,DB00334
,10752,DB00334,10017577,38,2811,35,2777,0.814223815,1.072603035,0.657503945,1.754276694,0.900368592,DB0033410017577_,0.104951053,0.070088437,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,olanzapine,DB00334
,10756,DB00334,10033371,54,2795,29,2783,0.007693323,1.853866423,1.155744591,3.029156599,0.028872655,DB0033410033371_,3.544860329,0.617273416,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,olanzapine,DB00334
,10759,DB00334,10044565,55,2794,44,2768,0.311646369,1.238318926,0.814833478,1.891577071,0.479038006,DB0033410044565_,0.73597534,0.213754755,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,olanzapine,DB00334
,10760,DB00334,10047899,72,2777,74,2738,0.866889102,0.95930307,0.680681999,1.351536627,0.94000454,DB0033410047899_,0.061870574,-0.041548227,NA,10047899,Weight increased,10022891,Investigations,Inv,olanzapine,DB00334
,10779,DB00814,10008479,89,8198,36,3379,1,1.018992494,0.683072979,1.548714172,1,DB0081410008479_,0,0.018814388,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,10780,DB09072,10008479,58,6413,24,2511,0.805946513,0.946244561,0.577302886,1.596175681,0.895042106,DB0907210008479_,0.110884516,-0.055254222,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,10784,DB00814,10022437,161,8126,72,3343,0.56078872,0.919935937,0.690364164,1.235884423,0.713366432,DB0081410022437_,0.337760061,-0.083451245,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,meloxicam,DB00814
,10789,DB09072,10037844,58,6413,15,2520,0.190432706,1.519406343,0.847979012,2.892202519,0.337121264,DB0907210037844_,1.087312579,0.418319695,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sodium oxybate,DB09072
,10791,DB00814,10042209,57,8230,15,3400,0.151672283,1.569841533,0.875444519,2.989873817,0.286277894,DB0081410042209_,1.250792282,0.45097468,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,meloxicam,DB00814
,10792,DB09072,10042209,109,6362,35,2500,0.350172165,1.223744432,0.826708565,1.851338915,0.519795305,DB0907210042209_,0.654320188,0.201915365,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,10797,DB00814,10048439,45,8242,7,3408,0.013439343,2.657898019,1.188290333,6.993273889,0.045046306,DB0081410048439_,3.10006429,0.977535592,NA,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,10798,DB09072,10048439,97,6374,8,2527,2.67815524478471e-07,4.806670462,2.340037206,11.46442286,4.40935237138529e-06,DB0907210048439_,12.33178273,1.570004633,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium oxybate,DB09072
,10802,DB09072,10000087,47,6424,19,2516,0.891289016,0.968836143,0.556483814,1.751657119,0.954816394,DB0907210000087_,0.046236214,-0.03165978,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,sodium oxybate,DB09072
,10803,DB06413,10012378,107,1449,37,637,0.260061633,1.271136655,0.856131953,1.923539551,0.421353078,DB0641310012378_,0.864284131,0.239911504,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,armodafinil,DB06413
,10804,DB06413,10012735,43,1513,16,658,0.668059708,1.168697822,0.639547216,2.23943655,0.798342817,DB0641310012735_,0.225217179,0.155890156,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,armodafinil,DB06413
,10808,DB09072,10019133,39,6432,16,2519,0.880853384,0.954614187,0.52019158,1.833197227,0.950123172,DB0907210019133_,0.051163648,-0.046448012,NA,10019133,Hangover,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,10809,DB06413,10041349,64,1492,35,639,0.263759554,0.78320939,0.505078438,1.232037375,0.425619272,DB0641310041349_,0.854210061,-0.244355199,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,armodafinil,DB06413
,10810,DB06413,10047700,56,1500,13,661,0.044786097,1.897780873,1.016361608,3.809844352,0.115163624,DB0641310047700_,2.161401341,0.640685242,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,armodafinil,DB06413
,10813,DB00108,10036807,201,9993,93,3202,0.004799487,0.692550696,0.537120999,0.898324453,0.019802922,DB0010810036807_,3.921925763,-0.367373836,NA,10036807,Progressive multifocal leukoencephalopathy,10021881,Infections and infestations,Infec,natalizumab,DB00108
,10821,DB00181,10022437,187,9669,102,5769,0.499784527,1.093863917,0.852860616,1.409555768,0.661507193,DB0018110022437_,0.413234422,0.089716306,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,10822,DB00656,10002368,32,11981,31,6588,0.025259103,0.567597598,0.33504376,0.962739814,0.074079277,DB0065610002368_,2.602619446,-0.566342566,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,10823,DB01238,10002368,23,5227,43,3459,4.07892798177336e-05,0.354004631,0.203251096,0.601859174,0.000370921,DB0123810002368_,7.899522324,-1.038445284,male,10002368,Anger,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,10825,DB01238,10012239,32,5218,43,3459,0.002856672,0.493351952,0.301511948,0.79984223,0.012993188,DB0123810012239_,4.343330089,-0.706532461,NA,10012239,Delusion,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,10827,DB01238,10033864,29,5221,42,3460,0.001392536,0.457621024,0.274321634,0.75382032,0.00722947,DB0123810033864_,4.929589506,-0.781713895,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,10830,DB00181,10019063,71,9785,75,5796,0.000552721,0.560790634,0.39888782,0.787699839,0.003353711,DB0018110019063_,5.697687835,-0.578407645,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,10831,DB00341,10000081,204,11201,69,4999,0.047433042,1.319422365,0.997416203,1.7634803,0.12026986,DB0034110000081_,2.118017228,0.277194039,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,10834,DB00341,10022116,42,11363,8,5060,0.02147839,2.337751488,1.083213316,5.76939777,0.065399304,DB0034110022116_,2.72724367,0.849189565,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,10849,DB00813,10013754,132,10440,102,10066,0.100223609,1.247741963,0.95485512,1.634352851,0.211113321,DB0081310013754_,1.555360224,0.221335488,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,10854,DB00813,10017413,44,10528,33,10135,0.304872723,1.283543098,0.798151148,2.082480771,0.471678361,DB0081310017413_,0.751457964,0.249624299,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,fentanyl,DB00813
,10855,DB00181,10017577,332,9524,153,5718,0.007538512,1.302745233,1.069345482,1.592759153,0.028403987,DB0018110017577_,3.561225752,0.264473756,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,10857,DB00327,10017577,78,6060,29,4233,0.002984968,1.878650705,1.20990792,2.990614006,0.013452185,DB0032710017577_,4.308613696,0.630553809,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,10858,DB00575,10017577,68,5176,48,3781,0.924696447,1.034856351,0.702907907,1.533987102,0.967584075,DB0057510017577_,0.032952959,0.034262625,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,10859,DB00813,10017577,90,10482,28,10140,2.57558546125723e-08,3.109536152,2.012876242,4.94094157,5.27869503697047e-07,DB0081310017577_,14.45441674,1.134473568,female,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,10860,DB00181,10020772,134,9722,83,5788,0.777818163,0.961198713,0.724103358,1.282134,0.878859624,DB0018110020772_,0.129130094,-0.039574114,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,baclofen,DB00181
,10862,DB00327,10020772,85,6053,49,4213,0.330993297,1.207344732,0.837686453,1.756924938,0.499693229,DB0032710020772_,0.693760911,0.188423512,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,hydromorphone,DB00327
,10863,DB00575,10020772,232,5012,132,3697,0.01981933,1.296402632,1.037882745,1.624718927,0.061334815,DB0057510020772_,2.791407653,0.259593223,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,clonidine,DB00575
,10864,DB00813,10020772,92,10480,95,10073,0.659542173,0.930840942,0.690162084,1.25490415,0.792035804,DB0081310020772_,0.233148681,-0.071666863,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,fentanyl,DB00813
,10868,DB00181,10039897,57,9799,79,5792,1.0680241576391e-06,0.426496385,0.297444477,0.60823885,1.51623089298102e-05,DB0018110039897_,11.09669789,-0.852151388,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,10869,DB00297,10039897,35,1637,17,862,0.883181861,1.084094546,0.58729025,2.076128207,0.951157897,DB0029710039897_,0.050075197,0.080745119,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,bupivacaine,DB00297
,10870,DB00327,10039897,48,6090,56,4206,0.008925696,0.592024098,0.39322153,0.888267427,0.032501479,DB0032710039897_,3.42646968,-0.524207939,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,10871,DB00575,10039897,56,5188,39,3790,0.835523344,1.048970798,0.683085942,1.625223308,0.914862473,DB0057510039897_,0.088981527,0.047809491,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,10872,DB00813,10039897,44,10528,40,10128,0.827477233,1.058224706,0.673181679,1.66786131,0.909224901,DB0081310039897_,0.0951628,0.056592698,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,10873,DB01234,10037844,996,30629,915,31973,0.006122037,1.136285894,1.036262423,1.246087483,0.024055272,DB0123410037844_,3.727401079,0.127764956,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,10876,DB00455,10012378,175,9226,58,5060,0.000689097,1.654752643,1.220427882,2.271873304,0.004039903,DB0045510012378_,5.511534673,0.503651538,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,loratadine,DB00455
,10877,DB01175,10012378,371,10353,144,4748,0.100427666,1.181532755,0.968989595,1.446977176,0.21146835,DB0117510012378_,1.553679939,0.166812541,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,10878,DB00455,10022437,211,9190,75,5043,0.001124502,1.543769374,1.177966393,2.041751894,0.006066816,DB0045510022437_,5.104921368,0.434227071,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,loratadine,DB00455
,10879,DB01175,10022437,233,10491,120,4772,0.270795992,0.883212283,0.703642096,1.113235893,0.433487981,DB0117510022437_,0.835891208,-0.124189696,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,10885,DB09072,10039897,40,6431,15,2520,1,1.044910771,0.563596784,2.040074315,1,DB0907210039897_,0,0.043931495,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,10886,DB00455,10047700,301,9100,111,5007,0.000298263,1.491998445,1.192866619,1.877206155,0.002008518,DB0045510047700_,6.210358126,0.40011646,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,10887,DB01175,10047700,348,10376,105,4787,0.000112019,1.529017652,1.222331169,1.925812616,0.000879591,DB0117510047700_,7.036053534,0.424625471,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,10889,DB00541,10029354,207,2927,311,3986,0.31025767,0.906393117,0.751622194,1.091388248,0.477659319,DB0054110029354_,0.738857523,-0.098282163,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,vincristine,DB00541
,10890,DB00635,10029354,239,32814,286,23508,6.33670920391345e-09,0.598690875,0.501637107,0.713985658,1.4903091553716e-07,DB0063510029354_,15.71911207,-0.513009882,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,10893,DB00541,10037660,233,2901,351,3946,0.256531689,0.902980571,0.756520429,1.076290267,0.417364165,DB0054110037660_,0.873796141,-0.102054242,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,vincristine,DB00541
,10894,DB00997,10037660,237,5094,212,3302,0.001067862,0.724696663,0.596365759,0.881020307,0.005813746,DB0099710037660_,5.14753019,-0.322002108,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,10898,DB00327,10001497,25,6113,55,4207,5.43336905047327e-07,0.312855299,0.186486546,0.511534113,8.36159868218325e-06,DB0032710001497_,11.69186092,-1.162014498,male,10001497,Agitation,10037175,Psychiatric disorders,Psych,hydromorphone,DB00327
,10903,DB00813,10047700,405,10167,216,9952,3.9589865655489e-13,1.835285768,1.548414831,2.180082559,1.87330264402256e-11,DB0081310047700_,24.70073303,0.607200201,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,10908,DB00182,10002855,248,4946,107,2745,0.035625686,1.286271105,1.016151704,1.637051653,0.096740179,DB0018210002855_,2.335726464,0.251747416,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,10909,DB00331,10002855,326,24620,148,20604,2.95281166374406e-10,1.843370442,1.511915832,2.256023111,8.95209395403835e-09,DB0033110002855_,18.53137837,0.611595658,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,metformin,DB00331
,10910,DB00182,10010264,146,5048,47,2805,0.001009947,1.726002091,1.230253696,2.459937465,0.005550167,DB0018210010264_,5.19392729,0.545807804,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,10911,DB00331,10010264,424,24522,197,20555,2.94446330234815e-12,1.804075023,1.51837028,2.149507242,1.22654861968655e-10,DB0033110010264_,22.82164671,0.590048008,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,10912,DB00182,10012378,233,4961,101,2751,0.046829731,1.279223217,1.003601316,1.639955543,0.119136612,DB0018210012378_,2.127484441,0.246253032,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,10913,DB00331,10012378,359,24587,174,20578,1.71827556856188e-09,1.726778305,1.435404783,2.083695666,4.55061695915858e-08,DB0033110012378_,16.90541792,0.546257421,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,metformin,DB00331
,10917,DB00182,10019211,321,4873,99,2753,8.05551570810358e-08,1.831678511,1.450319023,2.329917541,1.48641088373115e-06,DB0018210019211_,13.41914615,0.605232766,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,10918,DB09072,10019211,325,6146,85,2450,0.000485282,1.524132879,1.191014905,1.967976715,0.003016587,DB0907210019211_,5.803629252,0.421425645,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,10927,DB09072,10033664,85,6386,14,2521,0.001492306,2.396629794,1.34974014,4.577570324,0.0076567,DB0907210033664_,4.87217415,0.874063498,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,10932,DB00331,10036018,78,24868,105,20647,0.001324491,0.616782022,0.453862521,0.835173754,0.006942025,DB0033110036018_,4.97016173,-0.483239605,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,10933,DB00182,10042458,142,5052,70,2782,0.467943002,1.117080332,0.82989783,1.515229572,0.634488757,DB0018210042458_,0.454935711,0.110718435,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,10937,DB00182,10047895,112,5082,42,2810,0.033400305,1.474417972,1.022243068,2.161983936,0.092148145,DB0018210047895_,2.384357727,0.388263317,NA,10047895,Weight decreased,10022891,Investigations,Inv,amphetamine,DB00182
,10938,DB00182,10061428,60,5134,44,2808,0.149037557,0.745881487,0.495658027,1.130068513,0.282634262,DB0018210061428_,1.263601578,-0.293188555,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,amphetamine,DB00182
,10939,DB00635,10007882,247,32806,166,23628,0.515356615,1.071686298,0.876091617,1.313594069,0.675163786,DB0063510007882_,0.392799971,0.069233387,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,prednisone,DB00635
,10942,DB00108,10065042,118,10076,50,3245,0.123951121,0.760060302,0.540230648,1.082982631,0.247005068,DB0010810065042_,1.398346426,-0.274357505,NA,10065042,Immune reconstitution inflammatory syndrome,10021428,Immune system disorders,Immun,natalizumab,DB00108
,10943,DB00331,10028600,30,24916,42,20710,0.03251079,0.593723859,0.358676935,0.971777743,0.090213366,DB0033110028600_,2.405577681,-0.521340952,NA,10028600,Myocardial ischaemia,10007541,Cardiac disorders,Card,metformin,DB00331
,10949,DB00316,10001367,53,65421,36,36917,0.439609852,0.830784373,0.533815283,1.306315888,0.607941545,DB0031610001367_,0.497676544,-0.185384996,NA,10001367,Adrenal insufficiency,10014698,Endocrine disorders,Endo,acetaminophen,DB00316
,10950,DB00451,10001367,51,47220,29,15390,0.019097563,0.573178099,0.356333848,0.938201207,0.059589202,DB0045110001367_,2.820280895,-0.556558793,NA,10001367,Adrenal insufficiency,10014698,Endocrine disorders,Endo,levothyroxine,DB00451
,10951,DB06186,10001367,53,2156,98,3548,0.551792623,0.889987851,0.622000955,1.261467974,0.705698533,DB0618610001367_,0.348567139,-0.116547467,NA,10001367,Adrenal insufficiency,10014698,Endocrine disorders,Endo,ipilimumab,DB06186
,10953,DB00285,10007515,219,10732,72,3646,0.838535721,1.033367336,0.786107112,1.371859263,0.917091203,DB0028510007515_,0.086548354,0.032822728,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,venlafaxine,DB00285
,10954,DB00451,10007515,185,47086,130,15289,7.35765600111342e-11,0.462075926,0.366959926,0.583277861,2.45894453896079e-09,DB0045110007515_,19.82353363,-0.772026059,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,10957,DB00285,10011224,137,10814,31,3687,0.040022171,1.50667982,1.012201985,2.307248901,0.105726912,DB0028510011224_,2.246895812,0.409908435,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,venlafaxine,DB00285
,10960,DB00285,10037660,124,10827,39,3679,0.717959834,1.080379377,0.746795486,1.593969077,0.833478562,DB0028510037660_,0.182147298,0.077312254,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,10962,DB00285,10040047,54,10897,37,3681,0.001483584,0.493013045,0.318007644,0.771941134,0.007621619,DB0028510040047_,4.876766496,-0.707219646,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,venlafaxine,DB00285
,10963,DB00316,10040047,667,64807,556,36397,1.3765690724254e-11,0.673776175,0.600689989,0.755932258,5.12871978294849e-10,DB0031610040047_,21.39099486,-0.394857308,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,10964,DB06186,10040047,48,2161,84,3562,0.785705334,0.941895526,0.643801152,1.36459954,0.883734037,DB0618610040047_,0.123599125,-0.059860917,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ipilimumab,DB06186
,10966,DB00285,10068319,46,10905,11,3707,0.360370208,1.421488909,0.724341708,3.046758157,0.530261758,DB0028510068319_,0.634384511,0.35170485,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,venlafaxine,DB00285
,10967,DB00316,10068319,461,65013,131,36822,2.66669470872466e-13,1.993120892,1.637408487,2.439901539,1.30044657548845e-11,DB0031610068319_,25.0657283,0.689701698,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,10968,DB00451,10068319,392,46879,59,15360,1.64837619285179e-09,2.177060395,1.651246517,2.915040012,4.38538139970743e-08,DB0045110068319_,16.94240414,0.777975524,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,10970,DB00331,10003211,14,24932,39,20713,4.21272178113869e-05,0.298236223,0.149528887,0.561663275,0.000381569,DB0033110003211_,7.871218243,-1.209869412,male,10003211,Arteriosclerosis coronary artery,10007541,Cardiac disorders,Card,metformin,DB00331
,10971,DB00331,10048959,428,24518,268,20484,0.000226878,1.334244154,1.14130961,1.562020575,0.001602225,DB0033110048959_,6.436361887,0.288364955,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,10973,DB00321,10003239,181,7266,52,2798,0.064421793,1.340306878,0.976414579,1.867398959,0.151406191,DB0032110003239_,1.887789046,0.292898601,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,amitriptyline,DB00321
,10974,DB00331,10003239,595,24351,323,20429,2.67797150470234e-10,1.545395059,1.345522821,1.777432423,8.18493965129081e-09,DB0033110003239_,18.62097,0.435279579,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,10977,DB01132,10003239,31,1254,24,1506,0.132073082,1.55097347,0.875944308,2.777332521,0.258761252,DB0113210003239_,1.351849448,0.438882779,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pioglitazone,DB01132
,10979,DB14512,10003239,101,4743,37,2375,0.120649186,1.36683073,0.926016828,2.056584062,0.24233094,DB1451210003239_,1.417450967,0.312494724,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,mometasone furoate,DB14512
,10980,DB00126,10003246,81,10090,19,5926,0.000152568,2.50368608,1.503099153,4.375706371,0.001143665,DB0012610003246_,6.773517113,0.917764078,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,10982,DB00331,10003246,123,24823,62,20690,0.00109623,1.653536884,1.208182029,2.283021992,0.005938112,DB0033110003246_,5.126364012,0.50291656,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,10987,DB13961,10003246,89,9368,36,6378,0.007837835,1.683103739,1.129276844,2.556138999,0.029290892,DB1396110003246_,3.530478667,0.520639553,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,10989,DB00126,10005425,41,10130,11,5934,0.020506589,2.183283336,1.101053959,4.714058998,0.063031714,DB0012610005425_,2.764117288,0.780829861,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,ascorbic acid,DB00126
,10991,DB00331,10005425,70,24876,43,20709,0.130066185,1.355203876,0.913583497,2.030975762,0.255811267,DB0033110005425_,1.363315345,0.303951905,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,metformin,DB00331
,10996,DB13961,10005425,72,9385,27,6387,0.007402488,1.814742277,1.149948599,2.941982621,0.028003011,DB1396110005425_,3.575443226,0.595943462,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,fish oil,DB13961
,10998,DB00126,10007739,68,10103,31,5914,0.296034434,1.284028686,0.826949826,2.034478317,0.461894035,DB0012610007739_,0.772419776,0.250002546,NA,10007739,Cataract,10015919,Eye disorders,Eye,ascorbic acid,DB00126
,11000,DB00331,10007739,116,24830,68,20684,0.021451093,1.421028417,1.043842813,1.947422171,0.065346465,DB0033110007739_,2.728051934,0.351380847,NA,10007739,Cataract,10015919,Eye disorders,Eye,metformin,DB00331
,11005,DB13961,10007739,61,9396,35,6379,0.466186215,1.183195307,0.767440542,1.850061529,0.633021034,DB1396110007739_,0.457251629,0.168218666,NA,10007739,Cataract,10015919,Eye disorders,Eye,fish oil,DB13961
,11007,DB00321,10007882,55,7392,19,2831,0.794643466,1.108618417,0.646393049,1.981784584,0.88881717,DB0032110007882_,0.117863723,0.103114571,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,amitriptyline,DB00321
,11008,DB00331,10007882,146,24800,127,20625,0.714978274,0.956053606,0.74797227,1.223442438,0.831098018,DB0033110007882_,0.185007539,-0.044941295,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,metformin,DB00331
,11013,DB13961,10007882,78,9379,44,6370,0.354992518,1.203960733,0.820390343,1.786708581,0.524816689,DB1396110007882_,0.644706241,0.185616732,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,fish oil,DB13961
,11051,DB00321,10016173,273,7174,82,2768,0.053240957,1.284501039,0.995910143,1.671542731,0.131094186,DB0032110016173_,2.031839241,0.250370346,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,amitriptyline,DB00321
,11053,DB01036,10016173,74,1427,23,399,0.705541936,0.899643982,0.548570464,1.52592417,0.823597413,DB0103610016173_,0.194073445,-0.10575617,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,tolterodine,DB01036
,11054,DB01132,10016173,48,1237,44,1486,0.203718165,1.310366393,0.845796053,2.034336979,0.35352191,DB0113210016173_,1.039809816,0.270306788,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,pioglitazone,DB01132
,11056,DB13961,10016173,349,9108,202,6212,0.070087677,1.178337509,0.984963385,1.412612793,0.161396528,DB1396110016173_,1.823891036,0.164104554,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,fish oil,DB13961
,11057,DB14512,10016173,72,4772,32,2380,0.675102056,1.122147338,0.727942507,1.764469512,0.802998282,DB1451210016173_,0.219402704,0.115244116,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,mometasone furoate,DB14512
,11058,DB00126,10016454,68,10103,13,5932,6.56230752976744e-05,3.071073665,1.679713372,6.06636235,0.000555585,DB0012610016454_,7.495488815,1.122027228,female,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,ascorbic acid,DB00126
,11065,DB13961,10016454,68,9389,10,6404,1.57066274803219e-07,4.637753669,2.371871843,10.11331957,2.73456168769381e-06,DB1396110016454_,12.8095394,1.534230126,female,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,fish oil,DB13961
,11078,DB00331,10019022,31,24915,25,20727,1,1.031570268,0.589284211,1.822813976,1,DB0033110019022_,0,0.031082174,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,11085,DB00126,10020751,130,10041,47,5898,0.003721628,1.624654015,1.153480727,2.322748787,0.016089309,DB0012610020751_,4.129600248,0.485294879,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ascorbic acid,DB00126
,11086,DB00321,10020751,72,7375,9,2841,0.000417094,3.081763986,1.533566207,7.020230252,0.002651989,DB0032110020751_,5.93244533,1.125502156,female,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,amitriptyline,DB00321
,11087,DB00331,10020751,227,24719,114,20638,7.01839169390515e-06,1.662462549,1.32068614,2.102226192,7.96023411755326e-05,DB0033110020751_,9.438467054,0.508299966,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,metformin,DB00331
,11092,DB13961,10020751,127,9330,52,6362,0.001653302,1.665322716,1.194983106,2.349843366,0.008318732,DB1396110020751_,4.789245447,0.510018928,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,fish oil,DB13961
,11093,DB00126,10020772,171,10000,62,5883,0.000990055,1.622523033,1.204336808,2.21023086,0.005457969,DB0012610020772_,5.210678519,0.483982365,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ascorbic acid,DB00126
,11094,DB00321,10020772,94,7353,23,2827,0.060721705,1.571300196,0.985125376,2.60398806,0.144728873,DB0032110020772_,1.93289313,0.451903427,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,amitriptyline,DB00321
,11095,DB00331,10020772,344,24602,257,20495,0.201114333,1.11504267,0.944874021,1.317228485,0.350329054,DB0033110020772_,1.048882413,0.108892673,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,metformin,DB00331
,11100,DB14512,10020772,60,4784,20,2392,0.122102115,1.499922142,0.888830243,2.633751398,0.244455335,DB1451210020772_,1.408722666,0.405413201,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,mometasone furoate,DB14512
,11110,DB00126,10031282,54,10117,7,5938,1.29362014140706e-05,4.527375561,2.051999378,11.80192823,0.000136147,DB0012610031282_,8.901772663,1.510142425,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,11173,DB00126,10061428,207,9964,137,5808,0.25891787,0.880740432,0.704517307,1.103834808,0.419998532,DB0012610061428_,0.867504062,-0.126992325,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ascorbic acid,DB00126
,11174,DB00321,10061428,70,7377,36,2814,0.15601699,0.741742707,0.488145918,1.14446715,0.292181011,DB0032110061428_,1.230381767,-0.298752852,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,amitriptyline,DB00321
,11190,DB00331,10062060,46,24900,32,20720,0.495107871,1.19617939,0.745185603,1.941683734,0.657500651,DB0033110062060_,0.419309524,0.179132636,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,11225,DB00108,10044565,94,10100,37,3258,0.307535895,0.819509447,0.553419146,1.2362013,0.474681053,DB0010810044565_,0.745112168,-0.199049353,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,11226,DB00641,10003658,153,13971,175,12300,0.019348592,0.769728259,0.614654476,0.96307655,0.060225915,DB0064110003658_,2.809652534,-0.261717737,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,simvastatin,DB00641
,11228,DB00641,10007559,142,13982,188,12287,0.00024148,0.663770367,0.529237009,0.830977797,0.001685324,DB0064110007559_,6.38579739,-0.409819022,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,simvastatin,DB00641
,11230,DB00641,10011078,26,14098,67,12408,1.07475061341828e-06,0.341553996,0.208238521,0.54497348,1.52495653839134e-05,DB0064110011078_,11.09095955,-1.074249499,male,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,simvastatin,DB00641
,11232,DB00641,10028596,115,14009,150,12325,0.001575305,0.674522913,0.52373348,0.866887144,0.008001334,DB0064110028596_,4.828147055,-0.393749633,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,simvastatin,DB00641
,11233,DB01016,10028596,17,1084,34,1194,0.04740584,0.550875937,0.286871632,1.020587815,0.120224081,DB0101610028596_,2.118397933,-0.596245655,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,glyburide,DB01016
,11241,DB00316,10013916,105,65369,49,36904,0.313566781,1.20970884,0.853750119,1.735135245,0.481072526,DB0031610013916_,0.731737238,0.190379702,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,11244,DB00497,10013916,33,19234,18,16357,0.159182518,1.559082344,0.852364136,2.94209536,0.296388219,DB0049710013916_,1.216085134,0.444097407,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,11247,DB00395,10033295,43,2141,36,700,6.48802161900934e-05,0.390672782,0.242896033,0.631607394,0.000550299,DB0039510033295_,7.505048861,-0.939884945,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,carisoprodol,DB00395
,11248,DB00425,10033295,174,12521,64,7420,0.000916603,1.611106805,1.201228695,2.183967524,0.005128879,DB0042510033295_,5.272868073,0.476921399,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,11249,DB00555,10033295,182,6865,79,3407,0.351288228,1.143317032,0.87030595,1.513377146,0.52101064,DB0055510033295_,0.651984815,0.133933715,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lamotrigine,DB00555
,11250,DB00715,10033295,44,4799,65,2222,2.74048217566586e-09,0.313481026,0.2081111,0.468357877,6.97661733533919e-08,DB0071510033295_,16.47811657,-1.160016443,male,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,paroxetine,DB00715
,11251,DB01069,10033295,78,6622,22,2373,0.362099419,1.27047099,0.781018288,2.147365586,0.531767688,DB0106910033295_,0.631548561,0.23938769,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,promethazine,DB01069
,11252,DB00316,10041349,800,64674,382,36571,0.006695252,1.184255049,1.046275097,1.34218746,0.025857286,DB0031610041349_,3.655162874,0.169113926,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,11253,DB00395,10041349,53,2131,8,728,0.025565858,2.262830972,1.062221666,5.53699948,0.074753721,DB0039510041349_,2.593556285,0.816616672,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,carisoprodol,DB00395
,11254,DB00425,10041349,190,12505,107,7377,0.717037742,1.047529969,0.820753174,1.342772568,0.832718627,DB0042510041349_,0.183059477,0.046434982,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,11255,DB00497,10041349,286,18981,194,16181,0.01453604,1.256745443,1.042352001,1.517847734,0.048069283,DB0049710041349_,3.035111921,0.228525398,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,11256,DB00555,10041349,167,6880,83,3403,1,0.995203189,0.757775169,1.31537625,1,DB0055510041349_,0,-0.004808352,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,11257,DB00715,10041349,79,4764,55,2232,0.031197534,0.672984898,0.469157095,0.971241762,0.087335252,DB0071510041349_,2.438001098,-0.39603239,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,paroxetine,DB00715
,11258,DB01069,10041349,111,6589,39,2356,1,1.017690905,0.698409459,1.510669781,1,DB0106910041349_,0,0.017536242,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,11259,DB00186,10014625,112,16789,47,9961,0.048216087,1.413815941,0.996165417,2.034290153,0.12175031,DB0018610014625_,2.105782969,0.34629239,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,11260,DB00316,10014625,208,65266,174,36779,0.000145388,0.673670885,0.547887716,0.829065118,0.001097759,DB0031610014625_,6.814484127,-0.395013589,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,11263,DB00476,10014625,48,17209,14,6163,0.565678801,1.227843519,0.665289692,2.413258195,0.717238987,DB0047610014625_,0.332346178,0.205259394,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,11266,DB00999,10014625,43,21387,24,12215,1,1.023295029,0.606864457,1.763960338,1,DB0099910014625_,0,0.023027842,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,11267,DB01050,10014625,47,18061,23,9348,0.899879143,1.057659151,0.629037947,1.826060561,0.956571579,DB0105010014625_,0.044399659,0.056058118,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,11270,DB00316,10024690,127,65347,76,36877,0.714646612,0.943019251,0.703977907,1.270515006,0.830822716,DB0031610024690_,0.185338845,-0.058668582,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,acetaminophen,DB00316
,11276,DB00999,10024690,47,21383,18,12221,0.157371581,1.492308118,0.850070902,2.731452042,0.294036964,DB0099910024690_,1.224049792,0.400323994,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,11279,DB00186,10027417,49,16852,27,9981,0.812941477,1.074872799,0.658330766,1.78977374,0.899466113,DB0018610027417_,0.105953899,0.072202328,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,lorazepam,DB00186
,11285,DB00999,10027417,23,21407,61,12178,2.14325258462263e-11,0.214507467,0.126632742,0.351863174,7.7543557036209e-10,DB0099910027417_,20.97759622,-1.539410732,male,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,11286,DB01050,10027417,110,17998,56,9315,1,1.016630521,0.729686999,1.430198115,1,DB0105010027417_,0,0.016493749,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,ibuprofen,DB01050
,11288,DB00186,10033295,150,16751,94,9914,0.689857274,0.94443639,0.724028175,1.237162868,0.812952183,DB0018610033295_,0.207082987,-0.057166942,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,11289,DB00318,10033295,24,4259,30,1809,0.000129212,0.339866179,0.18957246,0.603192226,0.000992491,DB0031810033295_,6.915292291,-1.079203331,male,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,codeine,DB00318
,11290,DB00455,10033295,32,9369,22,5096,0.395262005,0.791188202,0.445141088,1.430758986,0.564978732,DB0045510033295_,0.570967192,-0.23421941,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,11291,DB00476,10033295,113,17144,55,6122,0.064846269,0.733674012,0.526265528,1.033389584,0.152194097,DB0047610033295_,1.882598617,-0.309690475,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,11294,DB00999,10033295,74,21356,97,12142,6.27791853669722e-08,0.433747596,0.315838789,0.593603436,1.18844140249972e-06,DB0099910033295_,13.64286786,-0.835292489,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,11295,DB01050,10033295,254,17854,134,9237,0.871510042,0.980662869,0.791156582,1.220053309,0.943380684,DB0105010033295_,0.058285383,-0.019526539,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,11297,DB00186,10046543,40,16861,25,9983,0.897877725,0.947324911,0.56039025,1.630365903,0.956338178,DB0018610046543_,0.044643686,-0.054113149,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,lorazepam,DB00186
,11298,DB00316,10046543,163,65311,73,36880,0.10360905,1.260897171,0.950758208,1.685868552,0.216423403,DB0031610046543_,1.530518591,0.231823508,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,11301,DB00476,10046543,68,17189,17,6160,0.217264334,1.433415978,0.832235774,2.604447861,0.370205693,DB0047610046543_,0.993696501,0.360060391,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,duloxetine,DB00476
,11303,DB00999,10046543,54,21376,15,12224,0.011797143,2.058640888,1.144408589,3.929420645,0.040616662,DB0099910046543_,3.203576915,0.722046002,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,hydrochlorothiazide,DB00999
,11304,DB01050,10046543,48,18060,20,9351,0.445088704,1.242608649,0.723164502,2.211858528,0.613107231,DB0105010046543_,0.48921543,0.217212919,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,ibuprofen,DB01050
,11306,DB00186,10047700,758,16143,303,9705,1.84068577708674e-09,1.503943031,1.3113868,1.728115285,4.84066289652076e-08,DB0018610047700_,16.84362907,0.408090347,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,11307,DB00476,10047700,1100,16157,296,5881,4.68081597682165e-06,1.352606135,1.184388881,1.548479647,5.58489550389274e-05,DB0047610047700_,9.792859743,0.302033202,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,11309,DB00972,10047700,55,2449,13,1166,0.024898163,2.01399143,1.080901963,4.035260845,0.073261481,DB0097210047700_,2.6137203,0.700118539,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,azelastine,DB00972
,11311,DB00227,10003658,41,2426,41,1762,0.175251455,0.726364149,0.457333136,1.153662665,0.317765287,DB0022710003658_,1.14644226,-0.319703808,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,lovastatin,DB00227
,11312,DB00584,10003658,23,2058,31,1843,0.169563168,0.664499582,0.368551991,1.181950606,0.31034139,DB0058410003658_,1.170082328,-0.40872103,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,enalapril,DB00584
,11313,DB00588,10003658,172,16352,117,8351,0.020557834,0.750812331,0.589259204,0.959338549,0.063159682,DB0058810003658_,2.762089128,-0.28659955,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,fluticasone propionate,DB00588
,11314,DB00227,10007559,21,2446,44,1759,3.74358952337568e-05,0.343307678,0.193159051,0.592274654,0.00034478,DB0022710007559_,7.972603633,-1.069128213,male,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,lovastatin,DB00227
,11315,DB00584,10007559,28,2053,40,1834,0.06579128,0.625408951,0.369927288,1.044010781,0.153772346,DB0058410007559_,1.872282043,-0.469349521,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,enalapril,DB00584
,11316,DB00588,10007559,160,16364,97,8371,0.208041306,0.843809658,0.650693746,1.098966145,0.358851969,DB0058810007559_,1.024845318,-0.169828334,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,fluticasone propionate,DB00588
,11327,DB00316,10019851,325,65149,155,36798,0.086396643,1.184288798,0.974659746,1.444148181,0.189036706,DB0031610019851_,1.66581407,0.169142424,NA,10019851,Hepatotoxicity,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,11328,DB00316,10022524,54,65420,28,36925,0.818180871,1.08855172,0.677338028,1.785102943,0.902944649,DB0031610022524_,0.102094024,0.084848116,NA,10022524,Intentional self-injury,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,11329,DB00181,10000087,89,9767,33,5838,0.01868256,1.612005135,1.068454804,2.485572368,0.058558441,DB0018110000087_,2.837730033,0.47747883,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,baclofen,DB00181
,11330,DB00295,10000087,122,14541,53,9549,0.012836529,1.511611646,1.085182918,2.130456053,0.043452437,DB0029510000087_,3.136088342,0.413176397,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,11333,DB00181,10012735,293,9563,151,5720,0.149019589,1.160650691,0.947754702,1.425927692,0.282629991,DB0018110012735_,1.263616688,0.148980789,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,baclofen,DB00181
,11335,DB00295,10028813,987,13676,491,9111,2.06996613224649e-07,1.339174581,1.196601237,1.500164384,3.5001003400514e-06,DB0029510028813_,12.56271892,0.29205344,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,11336,DB00297,10028813,84,1588,38,841,0.494489188,1.170646705,0.781092943,1.782213977,0.656977775,DB0029710028813_,0.420105089,0.157556335,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,bupivacaine,DB00297
,11338,DB00295,10039101,45,14618,21,9581,0.209802586,1.404462415,0.818856907,2.483680852,0.360930753,DB0029510039101_,1.01906916,0.339654607,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,11340,DB00181,10003549,327,9529,211,5660,0.364525813,0.920528551,0.769386447,1.103224664,0.534143293,DB0018110003549_,0.627091137,-0.082807262,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,11341,DB00321,10003549,145,7302,66,2784,0.243775253,0.837667256,0.619756495,1.142198352,0.402161083,DB0032110003549_,0.910902566,-0.177134327,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,11342,DB00512,10003549,84,4653,72,5026,0.169669872,1.260156844,0.906410523,1.755838041,0.310504253,DB0051210003549_,1.169557682,0.231236193,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,11343,DB01212,10003549,44,1975,44,1897,0.914241837,0.960503526,0.614713653,1.50081459,0.961618514,DB0121210003549_,0.039137462,-0.040297626,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ceftriaxone,DB01212
,11344,DB00321,10008531,53,7394,14,2836,0.272493075,1.451921741,0.792651229,2.83841639,0.435487357,DB0032110008531_,0.831289513,0.372888017,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,11345,DB00451,10008531,424,46847,103,15316,0.007022656,1.345812823,1.081858953,1.687181727,0.026856303,DB0045110008531_,3.617254742,0.29699816,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,11346,DB01068,10008531,114,13649,40,6800,0.058827556,1.419861507,0.981170907,2.092456705,0.141262156,DB0106810008531_,1.957137852,0.350559336,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,11348,DB05259,10008531,312,10958,66,2662,0.356567358,1.148372934,0.874803453,1.52653237,0.526242168,DB0525910008531_,0.641993776,0.1383461,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,11350,DB00264,10009866,31,29576,19,24873,0.320881205,1.372124707,0.750814574,2.571382355,0.48913286,DB0026410009866_,0.71512113,0.31636042,NA,10009866,Cold sweat,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,11352,DB00451,10009866,53,47218,10,15409,0.14181712,1.729506787,0.870529647,3.814451887,0.272285498,DB0045110009866_,1.300904138,0.547836273,NA,10009866,Cold sweat,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,11385,DB00181,10013700,227,9629,65,5806,3.03829966531299e-08,2.105663558,1.588340767,2.824350845,6.12906421356501e-07,DB0018110013700_,14.30505357,0.744630647,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,baclofen,DB00181
,11386,DB00264,10013700,595,29012,256,24636,9.90471802861914e-21,1.973584774,1.700091873,2.29648909,1.12703685446863e-18,DB0026410013700_,41.32693974,0.679851571,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,metoprolol,DB00264
,11387,DB00321,10013700,391,7056,100,2750,0.000156508,1.523842941,1.21463767,1.926266487,0.001169858,DB0032110013700_,6.75087322,0.421235395,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,amitriptyline,DB00321
,11388,DB00512,10013700,601,4136,268,4830,4.17874508060045e-39,2.618581128,2.249848256,3.05388566,1.56911877776547e-36,DB0051210013700_,82.44254917,0.962632617,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,vancomycin,DB00512
,11389,DB01068,10013700,238,13525,50,6790,2.11519499598309e-09,2.389592031,1.75261215,3.314889783,5.50201884902677e-08,DB0106810013700_,16.71556566,0.871122653,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,clonazepam,DB01068
,11390,DB01212,10013700,151,1868,50,1891,8.44766129746223e-13,3.056388806,2.190799797,4.325484132,3.82509521453566e-11,DB0121210013700_,23.98685266,1.11723409,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ceftriaxone,DB01212
,11391,DB05259,10013700,127,11143,20,2708,0.07497425,1.543137588,0.956232802,2.61671299,0.169806853,DB0525910013700_,1.773093647,0.433817739,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,glatiramer,DB05259
,11392,DB00264,10013754,50,29557,29,24863,0.114689312,1.450311674,0.899813749,2.377734393,0.233166415,DB0026410013754_,1.456002854,0.371778481,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,11394,DB00451,10013754,127,47144,33,15386,0.270343145,1.255985994,0.850241838,1.903266488,0.433026787,DB0045110013754_,0.83695569,0.227920917,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,11396,DB00996,10013754,152,38801,105,22320,0.153548282,0.832743766,0.64473568,1.078899423,0.288905983,DB0099610013754_,1.241653963,-0.183029288,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,11399,DB00512,10016173,37,4700,46,5052,0.581553405,0.864601619,0.544230292,1.365193608,0.729874722,DB0051210016173_,0.314882373,-0.145486434,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,vancomycin,DB00512
,11400,DB01068,10016173,517,13246,239,6601,0.365524778,1.077999421,0.920281763,1.265570813,0.535135278,DB0106810016173_,0.625235708,0.075106936,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,11402,DB00321,10017577,124,7323,32,2818,0.047008028,1.491166555,1.001283501,2.279518439,0.119468797,DB0032110017577_,2.124700058,0.399558737,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,11403,DB00451,10017577,692,46579,171,15248,0.000941593,1.324724551,1.117821977,1.577028202,0.005240788,DB0045110017577_,5.251283417,0.281204552,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,11405,DB00996,10017577,634,38319,279,22146,0.000137934,1.313301064,1.137845591,1.518888001,0.001049377,DB0099610017577_,6.85955892,0.272543864,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,11406,DB01068,10017577,272,13491,104,6736,0.023319772,1.305869949,1.035916474,1.656342362,0.069636386,DB0106810017577_,2.664468056,0.266869446,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,11408,DB05259,10017577,262,11008,55,2673,0.351807814,1.156709879,0.859122423,1.581522995,0.521545834,DB0525910017577_,0.65095812,0.145579664,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,11409,DB00321,10019211,363,7084,71,2779,1.87231463516199e-08,2.005548739,1.544905649,2.634507329,3.94657499480617e-07,DB0032110019211_,14.74524754,0.695917709,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,11410,DB00512,10019211,93,4644,50,5048,4.69343314081133e-05,2.021650692,1.415116687,2.917927484,0.000418619,DB0051210019211_,7.778550407,0.703914352,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,vancomycin,DB00512
,11411,DB01212,10019211,49,1970,23,1918,0.004032171,2.073823991,1.234005457,3.581268,0.017195689,DB0121210019211_,4.063096588,0.729394242,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ceftriaxone,DB01212
,11412,DB05259,10019211,384,10886,78,2650,0.169307636,1.198417315,0.933517221,1.554946078,0.309981625,DB0525910019211_,1.171242257,0.181001782,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,11413,DB00264,10020642,203,29404,181,24711,0.572071432,0.942571384,0.767040573,1.158955604,0.722122,DB0026410020642_,0.325561179,-0.059143624,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,11414,DB00321,10020642,59,7388,20,2830,0.705967064,1.129992312,0.66910565,1.985150728,0.823792781,DB0032110020642_,0.19383626,0.12221083,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,amitriptyline,DB00321
,11415,DB00451,10020642,424,46847,104,15315,0.00826589,1.332786742,1.072278996,1.669300968,0.030568966,DB0045110020642_,3.487769956,0.287272045,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,11416,DB00512,10020642,22,4715,41,5057,0.042302081,0.575540253,0.325969065,0.990739402,0.110308551,DB0051210020642_,2.204473835,-0.55244611,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,vancomycin,DB00512
,11417,DB00996,10020642,314,38639,163,22262,0.293871622,1.109904208,0.914972238,1.350407464,0.459581471,DB0099610020642_,0.777439049,0.104273712,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,11418,DB01068,10020642,160,13603,64,6776,0.153591666,1.245263111,0.924871071,1.693806217,0.288929564,DB0106810020642_,1.241572342,0.219346842,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,clonazepam,DB01068
,11420,DB05259,10020642,114,11156,28,2700,0.915413671,0.985376604,0.645477203,1.551335882,0.962143444,DB0525910020642_,0.03859173,-0.014731371,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,glatiramer,DB05259
,11422,DB00264,10023230,47,29560,26,24866,0.099365728,1.520623488,0.922329586,2.558668254,0.209911847,DB0026410023230_,1.561067612,0.41912044,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,11424,DB00451,10023230,108,47163,33,15386,0.844765491,1.067655556,0.71672542,1.629058386,0.921622917,DB0045110023230_,0.081619123,0.065465176,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,11426,DB00996,10023230,76,38877,20,22405,0.001328189,2.189929927,1.3236735,3.785887242,0.006957937,DB0099610023230_,4.967872249,0.783869547,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,11439,DB00264,10028334,414,29193,284,24608,0.008286254,1.228789752,1.052942948,1.435541992,0.030622733,DB0026410028334_,3.486012647,0.206029744,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,11440,DB00321,10028334,127,7320,32,2818,0.031974901,1.527859395,1.027113859,2.333381917,0.08906011,DB0032110028334_,2.418443741,0.423867667,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,amitriptyline,DB00321
,11442,DB00996,10028334,630,38323,271,22154,4.44322984373414e-05,1.343884242,1.162553799,1.556786812,0.000399625,DB0099610028334_,7.824984891,0.295564109,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,11443,DB01068,10028334,245,13518,70,6770,2.22930313967184e-05,1.752804566,1.336442219,2.32407703,0.000219096,DB0106810028334_,8.426000434,0.561217114,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,11445,DB05259,10028334,207,11063,54,2674,0.635921177,0.926535328,0.681522139,1.278370773,0.773708023,DB0525910028334_,0.256560708,-0.076303104,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,glatiramer,DB05259
,11448,DB00451,10028335,34,47237,18,15401,0.106371394,0.615852932,0.338064398,1.158648577,0.220701795,DB0045110028335_,1.510942831,-0.484747091,NA,10028335,Muscle spasticity,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,11450,DB00996,10028335,58,38895,46,22379,0.104080906,0.725492509,0.484012443,1.092980392,0.217167423,DB0099610028335_,1.527086686,-0.320904532,NA,10028335,Muscle spasticity,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,11453,DB05259,10028335,44,11226,9,2719,0.73103915,1.184101564,0.56960113,2.762151016,0.843569972,DB0525910028335_,0.170112426,0.168984314,NA,10028335,Muscle spasticity,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,11454,DB00321,10028813,393,7054,78,2772,1.00526268159089e-08,1.979844186,1.542540648,2.568218588,2.26401117114704e-07,DB0032110028813_,15.30095756,0.683018148,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,amitriptyline,DB00321
,11455,DB00512,10028813,188,4549,96,5002,5.63599732946956e-10,2.153198517,1.66920358,2.792391059,1.63874103766712e-08,DB0051210028813_,17.92675246,0.766954419,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,vancomycin,DB00512
,11456,DB01212,10028813,96,1923,45,1896,3.3654011898414e-05,2.102989425,1.452087934,3.085093864,0.000313909,DB0121210028813_,8.066407264,0.743359868,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ceftriaxone,DB01212
,11457,DB05259,10028813,358,10912,61,2667,0.008520375,1.434359696,1.086791297,1.920502766,0.031327185,DB0525910028813_,3.463269032,0.360718545,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,glatiramer,DB05259
,11461,DB00451,10034972,50,47221,11,15408,0.297264366,1.48312074,0.761884042,3.160342291,0.463190879,DB0045110034972_,0.769616045,0.394148476,NA,10034972,Photosensitivity reaction,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,11463,DB00996,10034972,42,38911,13,22412,0.049921895,1.860843037,0.979639881,3.778713317,0.124864118,DB0099610034972_,2.08052919,0.621029631,NA,10034972,Photosensitivity reaction,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,11467,DB00321,10037660,135,7312,58,2792,0.465092618,0.888780632,0.646563581,1.234811782,0.631951671,DB0032110037660_,0.458942357,-0.117904832,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,11468,DB01068,10037660,261,13502,111,6729,0.182325562,1.171819803,0.933007861,1.479702649,0.326793548,DB0106810037660_,1.118426658,0.158557927,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,11469,DB01212,10037660,120,1899,113,1828,0.892668179,1.022240738,0.777422969,1.344844565,0.9552998,DB0121210037660_,0.045730061,0.02199702,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ceftriaxone,DB01212
,11470,DB00181,10048010,58,9798,54,5817,0.018592465,0.637715443,0.431893473,0.942939702,0.058331694,DB0018110048010_,2.841609699,-0.44986311,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,11471,DB00264,10048010,63,29544,24,24868,0.000748125,2.209451703,1.360577508,3.69912496,0.004325009,DB0026410048010_,5.443341093,0.792744387,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,11472,DB00321,10048010,50,7397,16,2834,0.583461508,1.197247686,0.669213196,2.256170936,0.731448741,DB0032110048010_,0.312728135,0.180025327,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,11473,DB00451,10048010,142,47129,20,15399,0.000158023,2.319681773,1.44630862,3.914392769,0.001179843,DB0045110048010_,6.74237348,0.84143001,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,11475,DB00996,10048010,104,38849,92,22333,0.002903106,0.649883258,0.485890229,0.87031316,0.01315204,DB0099610048010_,4.331178368,-0.430962536,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,11476,DB01068,10048010,127,13636,35,6805,0.001397225,1.810779324,1.2354556,2.716792993,0.007248089,DB0106810048010_,4.927017387,0.593757318,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,11479,DB00181,10052904,153,9703,97,5774,0.644742566,0.938625765,0.72145121,1.226024449,0.780700604,DB0018110052904_,0.247563552,-0.063338426,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,11480,DB00264,10052904,156,29451,99,24793,0.031974214,1.326525374,1.024017915,1.725151092,0.08906011,DB0026410052904_,2.418443741,0.282563023,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,11481,DB00321,10052904,46,7401,7,2843,0.019829026,2.524015207,1.130118291,6.635491865,0.061347836,DB0032110052904_,2.791195385,0.925850969,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,amitriptyline,DB00321
,11482,DB00451,10052904,285,46986,62,15357,0.003233413,1.502373249,1.137294037,2.011993012,0.014377108,DB0045110052904_,4.242118074,0.407046024,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,11484,DB00996,10052904,246,38707,96,22329,0.001063305,1.478226258,1.162355498,1.892576889,0.005793135,DB0099610052904_,5.15108171,0.390842894,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,11485,DB01068,10052904,92,13671,39,6801,0.456721881,1.173510284,0.797691184,1.755436819,0.624103072,DB0106810052904_,0.471439746,0.1599995,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,11487,DB05259,10052904,104,11166,22,2706,0.651465658,1.145609302,0.716439119,1.910329388,0.785872774,DB0525910052904_,0.240960365,0.135936637,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,glatiramer,DB05259
,11507,DB00264,10061218,47,29560,17,24875,0.002338227,2.326427858,1.310953784,4.322967329,0.011050129,DB0026410061218_,4.505313219,0.844333983,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,11509,DB00451,10061218,101,47170,22,15397,0.093258155,1.498498572,0.937457146,2.497628416,0.200530973,DB0045110061218_,1.606786566,0.404463655,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,11511,DB00996,10061218,68,38885,14,22411,0.000194839,2.799317719,1.559152608,5.391685575,0.001409675,DB0099610061218_,6.56439612,1.029375716,female,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,11515,DB00181,10061428,101,9755,54,5817,0.559563251,1.115330509,0.792371113,1.584824643,0.712255105,DB0018110061428_,0.339319138,0.109150782,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,baclofen,DB00181
,11516,DB00512,10061428,59,4678,36,5062,0.007095119,1.773301612,1.14976453,2.769332476,0.027075378,DB0051210061428_,3.609130537,0.572843127,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,vancomycin,DB00512
,11517,DB01068,10061428,202,13561,95,6745,0.709671975,1.057588036,0.82319732,1.366739433,0.826831314,DB0106810061428_,0.190154578,0.055990877,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,clonazepam,DB01068
,11529,DB00264,10062355,202,29405,150,24742,0.259813522,1.133097214,0.912137695,1.410143276,0.421035661,DB0026410062355_,0.865037744,0.124954781,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,11531,DB00451,10062355,322,46949,80,15339,0.027301632,1.315013655,1.025743249,1.702827948,0.078665212,DB0045110062355_,2.542554253,0.27384705,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,11533,DB00996,10062355,233,38720,126,22299,0.583076671,1.064969992,0.853237412,1.334314113,0.731147872,DB0099610062355_,0.313139552,0.062946622,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,11534,DB01068,10062355,95,13668,47,6793,1,1.004574859,0.700139205,1.458781444,1,DB0106810062355_,0,0.004564426,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,11537,DB00005,10058080,345,127737,159,42260,0.00077548,0.717853451,0.592975473,0.872062587,0.004456384,DB0000510058080_,5.4134177,-0.331489838,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,11549,DB00331,10007515,157,24789,183,20569,0.00182101,0.711885349,0.57100598,0.886660605,0.009008235,DB0033110007515_,4.709616167,-0.339838407,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,metformin,DB00331
,11550,DB00335,10007515,45,8421,72,5393,1.34289926335942e-06,0.400289171,0.269073964,0.589956863,1.86565048294939e-05,DB0033510007515_,10.88931569,-0.915568066,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,atenolol,DB00335
,11551,DB00412,10007515,36,1028,57,1329,0.393916255,0.816573362,0.518209939,1.272092195,0.563856056,DB0041210007515_,0.57295628,-0.202638521,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,11552,DB00471,10007515,54,14135,27,5438,0.26503221,0.76943869,0.475720325,1.271861724,0.427018,DB0047110007515_,0.850929113,-0.262094005,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,montelukast,DB00471
,11553,DB00678,10007515,80,15519,67,10657,0.239283044,0.819960207,0.584673721,1.153009196,0.397042788,DB0067810007515_,0.923711227,-0.198499468,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,losartan,DB00678
,11555,DB01076,10007515,157,25590,211,25372,0.003984319,0.737744276,0.595733755,0.912028966,0.017027532,DB0107610007515_,4.072923723,-0.304158024,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,11556,DB00471,10008190,106,14083,41,5424,1,0.995741465,0.687221621,1.467034695,1,DB0047110008190_,0,-0.004267629,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,11557,DB00678,10008190,144,15455,105,10619,0.650561481,0.94230683,0.726730723,1.225180996,0.785075072,DB0067810008190_,0.241975933,-0.059424335,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,losartan,DB00678
,11558,DB01067,10008190,47,4314,60,4763,0.496063266,0.864876549,0.57617423,1.29150225,0.658403502,DB0106710008190_,0.41793731,-0.1451685,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,glipizide,DB01067
,11565,DB00678,10011078,40,15559,46,10678,0.020455408,0.596803017,0.380403473,0.9327998,0.062896314,DB0067810011078_,2.766267722,-0.516168175,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,losartan,DB00678
,11566,DB01076,10011078,84,25663,160,25423,8.86077049637274e-07,0.520099889,0.394272173,0.681884047,1.28854966803407e-05,DB0107610011078_,11.25940817,-0.653734391,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,11567,DB00331,10020919,43,24903,27,20725,0.280347618,1.325391918,0.800232066,2.231410312,0.444192841,DB0033110020919_,0.811496485,0.281708203,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,11569,DB00471,10020919,42,14147,9,5456,0.118324159,1.799758457,0.862771187,4.207900529,0.23870297,DB0047110020919_,1.432535304,0.587652466,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,montelukast,DB00471
,11571,DB00471,10016807,108,14081,35,5430,0.40039026,1.189913959,0.804814103,1.798106248,0.570219596,DB0047110016807_,0.561733736,0.173881001,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,montelukast,DB00471
,11572,DB00678,10016807,125,15474,61,10663,0.029658314,1.412053589,1.030514715,1.95258603,0.083950978,DB0067810016807_,2.477522249,0.345045091,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,11573,DB01067,10016807,41,4320,32,4791,0.157792507,1.420877512,0.871377342,2.335517803,0.294530326,DB0106710016807_,1.222373306,0.351274647,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,glipizide,DB01067
,11574,DB01076,10016807,216,25531,174,25409,0.041909787,1.235439973,1.006349678,1.518510251,0.109519187,DB0107610016807_,2.211655519,0.21142716,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,11581,DB00264,10022523,93,29514,96,24796,0.164884619,0.813895208,0.604990788,1.094541066,0.303969155,DB0026410022523_,1.190829046,-0.205923658,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,11582,DB00273,10022523,53,8428,7,2186,0.107694144,1.963685851,0.888011302,5.127144236,0.222683772,DB0027310022523_,1.502002576,0.674823243,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,topiramate,DB00273
,11584,DB01238,10022523,55,5195,28,3474,0.261582282,1.313516697,0.817081951,2.155180455,0.423210554,DB0123810022523_,0.859885459,0.272708042,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole,DB01238
,11587,DB00316,10073302,117,65357,50,36903,0.106779745,1.321247976,0.940821692,1.879245124,0.22128794,DB0031610073302_,1.508290528,0.278576726,NA,10073302,Exposure via ingestion,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,11592,DB00181,10010264,186,9670,111,5760,1,0.998127428,0.78294883,1.277288735,1,DB0018110010264_,0,-0.001874328,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,11593,DB00181,10013887,46,9810,27,5844,1,1.014927519,0.617036957,1.699883809,1,DB0018110013887_,0,0.0148172,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,11594,DB00181,10016322,171,9685,68,5803,0.004549755,1.506708675,1.128941774,2.030081631,0.018940499,DB0018110016322_,3.966452862,0.409927587,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,11603,DB00181,10061422,31,9825,31,5840,0.047723307,0.594448975,0.349071505,1.012228119,0.120813553,DB0018110061422_,2.113506809,-0.520120394,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,11609,DB00316,10000381,117,65357,63,36890,0.815882595,1.048245373,0.765026662,1.447919643,0.901316495,DB0031610000381_,0.103898813,0.047117693,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,11610,DB00316,10001551,315,65159,269,36684,7.70375327230719e-07,0.659238124,0.558192173,0.779077167,1.13728253166298e-05,DB0031610001551_,11.38428379,-0.416670468,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,acetaminophen,DB00316
,11611,DB00316,10037063,100,65374,50,36903,0.551563028,1.128997457,0.796022495,1.619111597,0.705570419,DB0031610037063_,0.348748698,0.121330033,NA,10037063,Prothrombin time prolonged,10022891,Investigations,Inv,acetaminophen,DB00316
,11615,DB00108,10006451,71,10123,15,3280,0.165079085,1.533585298,0.868744284,2.886900941,0.304247482,DB0010810006451_,1.189913825,0.427608326,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,natalizumab,DB00108
,11616,DB08868,10006451,99,9103,15,2496,0.029170081,1.809568602,1.043478985,3.361044153,0.082864497,DB0886810006451_,2.490548577,0.593088475,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,fingolimod,DB08868
,11617,DB08868,10012735,236,8966,62,2449,0.830385315,1.039719527,0.779907841,1.403605246,0.911043983,DB0886810012735_,0.093164103,0.038950991,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fingolimod,DB08868
,11620,DB08868,10033371,267,8935,76,2435,0.738603574,0.957418819,0.736288211,1.257244066,0.84956218,DB0886810033371_,0.163034144,-0.043514346,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,11623,DB00108,10047895,71,10123,28,3267,0.410757945,0.818349558,0.520589439,1.319099477,0.58013356,DB0010810047895_,0.544496926,-0.200465701,NA,10047895,Weight decreased,10022891,Investigations,Inv,natalizumab,DB00108
,11624,DB08868,10047895,112,9090,38,2473,0.270097759,0.801868989,0.548843975,1.194486317,0.43273526,DB0886810047895_,0.837629148,-0.22081004,NA,10047895,Weight decreased,10022891,Investigations,Inv,fingolimod,DB08868
,11626,DB08868,10047899,143,9059,12,2499,6.77082166439892e-06,3.28713985,1.820630129,6.52152772,7.71941216433422e-05,DB0886810047899_,9.469187248,1.19001784,female,10047899,Weight increased,10022891,Investigations,Inv,fingolimod,DB08868
,11630,DB08868,10060795,143,9059,57,2454,0.018584485,0.679628585,0.494874519,0.944032447,0.058313619,DB0886810060795_,2.841919612,-0.386208828,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,fingolimod,DB08868
,11633,DB00264,10000087,359,29248,198,24694,1.26459735935815e-06,1.530805691,1.282305544,1.831763096,1.76339212682912e-05,DB0026410000087_,10.94568617,0.425794192,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,11634,DB00316,10000087,776,64698,324,36629,3.37567083346601e-06,1.355968624,1.188763625,1.549458711,4.18930632000255e-05,DB0031610000087_,10.0803903,0.30451605,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,11636,DB00497,10000087,237,19030,144,16231,0.001335422,1.403742157,1.135112165,1.740887428,0.006986777,DB0049710000087_,4.963735953,0.33914164,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,11637,DB00641,10000087,180,13944,92,12383,1.31878641145765e-05,1.737452092,1.342454664,2.261531694,0.000138519,DB0064110000087_,8.884505334,0.552419725,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,11638,DB00682,10000087,309,19150,117,16247,1.16189801367638e-14,2.240554211,1.803515187,2.798887,6.79432464727109e-13,DB0068210000087_,28.01751856,0.806723251,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,11639,DB00695,10000087,435,27614,195,20333,4.44478202592227e-09,1.642559861,1.382718869,1.956836814,1.07927109054381e-07,DB0069510000087_,16.04180975,0.496255916,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,11640,DB00722,10000087,327,25076,185,25847,3.73507506408267e-11,1.821880082,1.515337984,2.195824061,1.30727627242894e-09,DB0072210000087_,20.45532005,0.59986898,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,11641,DB00741,10000087,54,4040,27,3147,0.070937184,1.557826665,0.961757745,2.57859252,0.162959613,DB0074110000087_,1.814252881,0.443291686,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,hydrocortisone,DB00741
,11642,DB00788,10000087,147,9209,44,5017,0.000321037,1.820035057,1.289106886,2.615267488,0.002132537,DB0078810000087_,6.150442694,0.598855763,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,11643,DB00864,10000087,43,6826,47,8345,0.597248448,1.118476946,0.721118256,1.730848734,0.742475406,DB0086410000087_,0.297765533,0.11196789,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,11644,DB00956,10000087,69,5745,44,3423,0.769290105,0.934365516,0.629418903,1.399950736,0.873663127,DB0095610000087_,0.135060416,-0.067887572,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,hydrocodone,DB00956
,11645,DB01050,10000087,261,17847,97,9274,0.004951134,1.398188116,1.101785984,1.786359062,0.020317003,DB0105010000087_,3.896297157,0.335177196,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,11648,DB11089,10000087,138,10037,77,8330,0.0057305,1.48737135,1.115660637,1.995195654,0.022820423,DB1108910000087_,3.780099412,0.397010368,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,11649,DB14500,10000087,99,7710,34,4039,0.034489702,1.525321372,1.021585063,2.327878371,0.094389277,DB1450010000087_,2.360327806,0.422205124,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,11671,DB00482,10017955,55,8204,41,3030,0.001100107,0.495461432,0.323929424,0.763261296,0.005956598,DB0048210017955_,5.123255762,-0.702265765,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,celecoxib,DB00482
,11672,DB00497,10017955,80,19187,107,16268,0.002469047,0.633933848,0.468071833,0.855600305,0.011554012,DB0049710017955_,4.460722505,-0.45581067,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,11673,DB00641,10017955,167,13957,201,12274,0.003178301,0.730672097,0.590626697,0.902952742,0.014184846,DB0064110017955_,4.255581081,-0.313790487,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,11674,DB00722,10017955,204,25199,306,25726,2.24076349440433e-05,0.680617261,0.566770446,0.815940394,0.000220181,DB0072210017955_,8.421059758,-0.384755156,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,11676,DB00788,10017955,78,9278,103,4958,2.24558601635096e-09,0.404702647,0.296980058,0.54960836,5.79815603534235e-08,DB0078810017955_,16.6631408,-0.904602687,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,11677,DB00956,10017955,41,5773,33,3434,0.22736303,0.73908485,0.454953769,1.208916549,0.382619197,DB0095610017955_,0.960715049,-0.302342548,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,hydrocodone,DB00956
,11680,DB14500,10017955,71,7738,47,4026,0.206016841,0.78600549,0.534987795,1.164099969,0.356492869,DB1450010017955_,1.031441041,-0.240791501,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,11682,DB00316,10018830,79,65395,56,36897,0.209203702,0.79596559,0.557924497,1.142066899,0.360242962,DB0031610018830_,1.020976582,-0.228199323,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,11687,DB00682,10018830,63,19396,75,16289,0.04855951,0.705455749,0.496188761,1.000197659,0.122358886,DB0068210018830_,2.100796867,-0.348911232,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,11688,DB00695,10018830,73,27976,45,20483,0.401478144,1.187714675,0.807792899,1.76324799,0.571258216,DB0069510018830_,0.559913955,0.17203102,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,11689,DB00722,10018830,30,25373,41,25991,0.237262054,0.749535647,0.451769705,1.230520709,0.394611792,DB0072210018830_,0.929852802,-0.288301402,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,11694,DB01050,10018830,33,18075,37,9334,0.001427562,0.460582294,0.278947879,0.757583581,0.007379245,DB0105010018830_,4.909083939,-0.775263734,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,11700,DB00316,10022437,1065,64409,523,36430,0.008450369,1.151779702,1.035493741,1.28226239,0.031118437,DB0031610022437_,3.469954814,0.141308313,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,11702,DB00482,10022437,147,8112,60,3011,0.528680591,0.909400747,0.667030949,1.253087487,0.686054125,DB0048210022437_,0.376798755,-0.094969416,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,celecoxib,DB00482
,11703,DB00497,10022437,287,18980,242,16133,0.964949909,1.008057962,0.845441268,1.202711704,1,DB0049710022437_,0,0.00802567,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,11704,DB00682,10022437,293,19166,193,16171,0.007825781,1.280891041,1.0631149,1.546068636,0.029259467,DB0068210022437_,3.5315521,0.247555962,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,11705,DB00695,10022437,454,27595,230,20298,3.37236108181818e-06,1.451934769,1.234894963,1.710851533,4.18618706189331e-05,DB0069510022437_,10.08113515,0.372896991,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,11706,DB00722,10022437,429,24974,330,25702,7.67542975915159e-05,1.337882486,1.15508821,1.550735371,0.000635629,DB0072210022437_,7.360895366,0.29108813,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,11707,DB00741,10022437,55,4039,45,3129,0.839272981,0.946884106,0.625032829,1.440919944,0.917649347,DB0074110022437_,0.085939936,-0.054578573,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,hydrocortisone,DB00741
,11708,DB00788,10022437,195,9161,81,4980,0.048189745,1.308674515,1.002495394,1.721442527,0.121701331,DB0078810022437_,2.106185344,0.269014804,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,naproxen,DB00788
,11709,DB00864,10022437,39,6830,49,8343,0.914890372,0.972230786,0.620819231,1.513389346,0.961903265,DB0086410022437_,0.03884139,-0.028162069,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,tacrolimus,DB00864
,11710,DB00956,10022437,160,5654,78,3389,0.153930626,1.229476107,0.928887374,1.63879708,0.289407854,DB0095610022437_,1.239918325,0.206588149,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,hydrocodone,DB00956
,11711,DB01050,10022437,315,17793,158,9213,0.769272487,1.032298667,0.848586206,1.259816367,0.873663127,DB0105010022437_,0.135060416,0.031788031,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,11714,DB11089,10022437,146,10029,114,8293,0.66103026,1.05902627,0.821723711,1.367577223,0.793169926,DB1108910022437_,0.231717798,0.057349873,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,docusate,DB11089
,11715,DB14500,10022437,145,7664,56,4017,0.060682461,1.357111982,0.987931163,1.886552985,0.144661572,DB1450010022437_,1.933358249,0.305358899,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,potassium,DB14500
,11738,DB00316,10019670,50,65424,27,36926,0.905922148,1.045207144,0.641893619,1.736633604,0.957985383,DB0031610019670_,0.042922759,0.044215089,NA,10019670,Hepatic function abnormal,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,11739,DB00316,10010305,666,64808,516,36437,7.78561099148361e-08,0.725695495,0.645432341,0.816267454,1.44319312349187e-06,DB0031610010305_,13.44865245,-0.320624781,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,11741,DB00316,10019063,289,65185,217,36736,0.001586051,0.750577523,0.62690826,0.899641696,0.0080396,DB0031610019063_,4.823376001,-0.286912337,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,11744,DB00316,10043071,445,65029,270,36683,0.348525886,0.929725591,0.797018803,1.086109737,0.518039476,DB0031610043071_,0.657703832,-0.0728658,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,11746,DB00181,10011906,261,9595,196,5675,0.014068641,0.787624814,0.649942735,0.955652437,0.04677683,DB0018110011906_,3.062367291,-0.238733427,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,11747,DB00252,10011906,80,2152,87,1821,0.113734686,0.778157181,0.563334862,1.073794802,0.231745444,DB0025210011906_,1.462115733,-0.250826743,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,phenytoin,DB00252
,11748,DB00273,10011906,171,8310,54,2139,0.210545658,0.815118911,0.594615384,1.132708482,0.361831414,DB0027310011906_,1.016576884,-0.204421274,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,11749,DB00321,10011906,302,7145,159,2691,0.001133147,0.715379338,0.585300279,0.876973168,0.006104064,DB0032110011906_,5.098800573,-0.334942334,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,11750,DB00656,10011906,398,11615,398,6221,1.36203879186655e-17,0.535600823,0.463364549,0.619167438,1.12229434621355e-15,DB0065610011906_,34.42340128,-0.624366129,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,11751,DB00669,10011906,43,6334,20,1077,0.000493878,0.3656226,0.209536749,0.658833765,0.003061171,DB0066910011906_,5.788957756,-1.006153626,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,11752,DB00915,10011906,63,1392,81,970,0.000466297,0.542136202,0.379642277,0.771238844,0.002913877,DB0091510011906_,5.838270716,-0.612238014,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,amantadine,DB00915
,11753,DB01068,10011906,506,13257,389,6451,6.99019654313418e-11,0.632969853,0.551629998,0.726776621,2.343588216024e-09,DB0106810011906_,19.87158266,-0.457332483,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,11754,DB01075,10011906,1073,18875,856,10241,8.83780179869549e-16,0.680092921,0.619081024,0.747324771,5.94121790994145e-14,DB0107510011906_,30.45427715,-0.385525842,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,11755,DB01104,10011906,526,14937,428,6858,2.84075266617955e-17,0.564300286,0.494107753,0.644631938,2.27303451538902e-15,DB0110410011906_,33.71766067,-0.572168747,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,11756,DB01202,10011906,286,6428,317,5401,0.000930798,0.758084988,0.641155084,0.896056493,0.005190625,DB0120210011906_,5.260901092,-0.276959778,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,11759,DB00060,10033775,167,9341,35,2430,0.291917597,1.241231414,0.855362456,1.847079382,0.457382812,DB0006010033775_,0.782234576,0.216103963,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,11774,DB00186,10022523,66,16835,51,9957,0.151782297,0.765425027,0.522622205,1.126615894,0.286407797,DB0018610022523_,1.25033862,-0.267324009,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,11775,DB00555,10022523,129,6918,49,3437,0.126695064,1.307959152,0.931867123,1.861356521,0.251040651,DB0055510022523_,1.382140395,0.268468023,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lamotrigine,DB00555
,11776,DB00203,10003988,398,13480,136,8802,1.73562097967957e-11,1.910833441,1.565897639,2.343380811,6.3671734055656e-10,DB0020310003988_,21.17469529,0.647539504,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,11777,DB00559,10003988,167,9492,31,3275,0.000973134,1.858698495,1.258098743,2.828332163,0.005387852,DB0055910003988_,5.223608578,0.619876509,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bosentan,DB00559
,11778,DB00695,10003988,658,27391,319,20209,5.58828569698214e-10,1.521836143,1.327636363,1.747189476,1.62817512606839e-08,DB0069510003988_,17.93322091,0.419917594,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,11779,DB00863,10003988,263,10410,104,5736,0.00407682,1.39338935,1.103554095,1.769982754,0.01735091,DB0086310003988_,4.054110336,0.33173916,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,11780,DB01098,10003988,175,7974,132,7077,0.166031835,1.176609125,0.93104822,1.489769146,0.305479692,DB0109810003988_,1.185871979,0.162636679,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,11789,DB00203,10008479,794,13084,211,8727,3.94515490670384e-36,2.50982042,2.148332438,2.942298531,1.29622995903388e-33,DB0020310008479_,75.72584805,0.920211205,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,11790,DB00559,10008479,365,9294,82,3224,0.000320577,1.544108761,1.207675632,1.993426926,0.002130291,DB0055910008479_,6.151496791,0.43444689,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,11791,DB00695,10008479,668,27381,337,20191,1.24762503277337e-08,1.461676356,1.278687297,1.673308145,2.7500062043143e-07,DB0069510008479_,15.10649248,0.379583966,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,11792,DB00863,10008479,219,10454,81,5759,0.002256809,1.489408251,1.146748443,1.950509776,0.01073572,DB0086310008479_,4.534178798,0.398378894,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,11793,DB01098,10008479,119,8030,114,7095,0.552173481,0.922327215,0.705873612,1.205606176,0.706031033,DB0109810008479_,0.348096086,-0.080855222,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,11795,DB00497,10010071,70,19197,70,16305,0.350623403,0.849357136,0.600600295,1.201155779,0.52033289,DB0049710010071_,0.653286498,-0.163275526,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,11809,DB00497,10013573,427,18840,319,16056,0.081003321,1.140750031,0.982854023,1.325091213,0.180054863,DB0049710013573_,1.714493679,0.131685968,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,11810,DB00559,10013573,510,9149,116,3190,2.75689421703572e-05,1.532965912,1.245347773,1.899673562,0.000263413,DB0055910013573_,8.24178675,0.427204363,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,bosentan,DB00559
,11811,DB00863,10013573,417,10256,163,5677,0.000167893,1.416056489,1.175173134,1.71275719,0.001243294,DB0086310013573_,6.689991106,0.347875888,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,11812,DB01098,10013573,280,7869,210,6999,0.065941092,1.185905381,0.985098466,1.429337493,0.154047159,DB0109810013573_,1.870496493,0.170506518,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,11814,DB00316,10013774,155,65319,35,36918,1.29384172369588e-07,2.502984752,1.724778055,3.723888006,2.29710433686905e-06,DB0031610013774_,12.98386121,0.917483921,NA,10013774,Dry eye,10015919,Eye disorders,Eye,acetaminophen,DB00316
,11817,DB00695,10013774,98,27951,21,20507,1.29744989090006e-08,3.423706157,2.120038728,5.779269681,2.83969587384111e-07,DB0069510013774_,15.07439869,1.230723636,female,10013774,Dry eye,10015919,Eye disorders,Eye,furosemide,DB00695
,11819,DB00999,10013774,59,21371,19,12220,0.033168389,1.775569565,1.043010443,3.155577621,0.09165592,DB0099910013774_,2.389713715,0.574121253,NA,10013774,Dry eye,10015919,Eye disorders,Eye,hydrochlorothiazide,DB00999
,11821,DB00316,10016807,359,65115,130,36823,8.58989337512617e-06,1.561662909,1.273799107,1.924437318,9.50875331081033e-05,DB0031610016807_,9.260712689,0.445751221,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,11822,DB00497,10016807,101,19166,57,16318,0.013050775,1.508606435,1.078997776,2.127049289,0.044018941,DB0049710016807_,3.123135256,0.411186334,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,11823,DB00695,10016807,755,27294,385,20143,3.06836231029669e-09,1.447236173,1.276585452,1.642751758,7.73639360442671e-08,DB0069510016807_,16.37474511,0.36965565,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,11824,DB00863,10016807,96,10577,21,5819,3.93502373950577e-05,2.514877573,1.554170082,4.25223795,0.000359673,DB0086310016807_,7.930314492,0.922224124,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,ranitidine,DB00863
,11825,DB00999,10016807,129,21301,56,12183,0.091720421,1.317505675,0.954825991,1.838190656,0.198026307,DB0099910016807_,1.619355394,0.275740309,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,11826,DB00203,10019303,291,13587,89,8849,6.88250786506196e-11,2.129407324,1.671223002,2.735616147,2.31338515643419e-09,DB0020310019303_,19.88455395,0.755843689,NA,10019303,Heart rate increased,10022891,Investigations,Inv,sildenafil,DB00203
,11827,DB00497,10019303,72,19195,48,16327,0.199920177,1.275868968,0.872776007,1.879716644,0.348892285,DB0049710019303_,1.052992043,0.24362749,NA,10019303,Heart rate increased,10022891,Investigations,Inv,oxycodone,DB00497
,11828,DB00695,10019303,256,27793,96,20432,5.43911939351142e-09,1.960358426,1.543482574,2.5070216,1.29558000234207e-07,DB0069510019303_,15.85913718,0.673127327,NA,10019303,Heart rate increased,10022891,Investigations,Inv,furosemide,DB00695
,11829,DB00863,10019303,56,10617,32,5808,0.824184208,0.957349399,0.608559155,1.529545843,0.906856118,DB0086310019303_,0.097771477,-0.043586856,NA,10019303,Heart rate increased,10022891,Investigations,Inv,ranitidine,DB00863
,11830,DB00999,10019303,139,21291,35,12204,3.81276504750682e-06,2.276370463,1.560545584,3.401774877,4.65483182878387e-05,DB0099910019303_,9.975019682,0.822582272,NA,10019303,Heart rate increased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,11831,DB01098,10019303,50,8099,20,7189,0.002447121,2.218915497,1.295960371,3.939177113,0.011469787,DB0109810019303_,4.468038945,0.797018562,NA,10019303,Heart rate increased,10022891,Investigations,Inv,rosuvastatin,DB01098
,11832,DB00497,10021097,272,18995,327,16048,1.99031598951686e-05,0.7027667,0.595301615,0.829115888,0.000198956,DB0049710021097_,8.522426298,-0.352730306,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,oxycodone,DB00497
,11833,DB00695,10021097,842,27207,729,19799,0.000806144,0.840524998,0.758963609,0.931022333,0.00460491,DB0069510021097_,5.38063213,-0.173728585,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,furosemide,DB00695
,11834,DB00863,10021097,140,10533,135,5705,2.96809633313902e-06,0.5616839,0.439263572,0.718530112,3.75439904314529e-05,DB0086310021097_,10.18999723,-0.576816043,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ranitidine,DB00863
,11835,DB00999,10021097,300,21130,296,11943,2.77715809879203e-11,0.572893058,0.485463121,0.67604463,9.8979797459998e-10,DB0099910021097_,20.73352026,-0.557056215,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,hydrochlorothiazide,DB00999
,11836,DB01098,10021097,110,8039,123,7086,0.074267329,0.788306734,0.602638236,1.030047478,0.168626744,DB0109810021097_,1.780067625,-0.237868008,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,rosuvastatin,DB01098
,11837,DB00316,10021789,577,64897,279,36674,0.034927654,1.168732785,1.010680127,1.353982372,0.095290196,DB0031610021789_,2.350828347,0.155920072,NA,10021789,Infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,11838,DB00497,10021789,138,19129,114,16261,0.849217457,1.029036045,0.796372785,1.331792306,0.924963467,DB0049710021789_,0.078001038,0.028622485,NA,10021789,Infection,10021881,Infections and infestations,Infec,oxycodone,DB00497
,11839,DB00559,10021789,139,9520,55,3251,0.361663108,0.863072708,0.625533066,1.205033985,0.531460778,DB0055910021789_,0.632125878,-0.147256341,NA,10021789,Infection,10021881,Infections and infestations,Infec,bosentan,DB00559
,11840,DB00695,10021789,307,27742,165,20363,0.001219806,1.365699981,1.125608362,1.661855215,0.006483842,DB0069510021789_,5.038441971,0.311667104,NA,10021789,Infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,11841,DB00863,10021789,117,10556,51,5789,0.194311955,1.258134036,0.896582194,1.787091068,0.342141596,DB0086310021789_,1.072530606,0.229629699,NA,10021789,Infection,10021881,Infections and infestations,Infec,ranitidine,DB00863
,11842,DB00999,10021789,189,21241,78,12161,0.015131056,1.387258696,1.059101937,1.831722934,0.049656008,DB0099910021789_,3.002635892,0.327329639,NA,10021789,Infection,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,11843,DB00203,10028836,96,13782,47,8891,0.143765484,1.317669254,0.919207227,1.91187808,0.275167534,DB0020310028836_,1.290375153,0.27586446,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,11844,DB00316,10028836,378,65096,119,36834,7.02904647704026e-09,1.797367121,1.458389314,2.228544876,1.63358520467731e-07,DB0031610028836_,15.62731854,0.586322884,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,11845,DB00559,10028836,41,9618,11,3295,0.527551126,1.276879901,0.64362688,2.757916837,0.685112715,DB0055910028836_,0.378171907,0.244419525,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bosentan,DB00559
,11846,DB00695,10028836,149,27900,64,20464,0.000283079,1.707601498,1.265033998,2.327666132,0.001926151,DB0069510028836_,6.252231684,0.535089753,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,11847,DB00863,10028836,74,10599,16,5824,0.00034682,2.541248437,1.464651799,4.678990478,0.002277616,DB0086310028836_,6.084625792,0.932655471,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,11848,DB00999,10028836,127,21303,32,12207,1.01648959956781e-05,2.274112711,1.531969397,3.466459371,0.000110179,DB0099910028836_,9.113403433,0.821589959,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,11849,DB01098,10028836,43,8106,32,7177,0.487987322,1.189733322,0.734611736,1.944979886,0.65161659,DB0109810028836_,0.428298943,0.173729183,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,11850,DB00203,10030095,514,13364,187,8751,2.02600492519709e-12,1.799828314,1.516035552,2.144091333,8.66615776384142e-11,DB0020310030095_,23.16901049,0.587691279,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,11851,DB00316,10030095,368,65106,158,36795,0.003568822,1.316308367,1.089006389,1.597016904,0.015568251,DB0031610030095_,4.162521601,0.274831127,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,11852,DB00497,10030095,79,19188,62,16313,0.672510973,1.083303532,0.766464895,1.536970612,0.801148946,DB0049710030095_,0.221708399,0.080015198,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,11853,DB00559,10030095,205,9454,84,3222,0.17203053,0.83171834,0.64002069,1.088933312,0.313492962,DB0055910030095_,1.159978368,-0.184261429,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,11854,DB00695,10030095,581,27468,328,20200,0.000144459,1.302638672,1.134321052,1.497934764,0.001092537,DB0069510030095_,6.819252467,0.264391955,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,11855,DB00863,10030095,69,10604,29,5811,0.245369426,1.303861489,0.832559318,2.089729349,0.404169535,DB0086310030095_,0.905920847,0.265330238,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,11856,DB00999,10030095,129,21301,57,12182,0.108853141,1.294296193,0.939787674,1.801838871,0.224320253,DB0099910030095_,1.494680549,0.257967067,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,11857,DB01098,10030095,41,8108,43,7166,0.44487373,0.842721712,0.535064299,1.325487742,0.612963568,DB0109810030095_,0.489449777,-0.171118492,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,11858,DB01098,10037660,130,8019,97,7112,0.203816974,1.188606131,0.904848163,1.565661154,0.353598415,DB0109810037660_,1.03959343,0.172781302,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,11859,DB00203,10039203,37,13841,39,8899,0.033914458,0.610007609,0.378009702,0.982768731,0.09321777,DB0020310039203_,2.372816912,-0.494283848,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,11860,DB00316,10039203,197,65277,69,36884,0.000531299,1.613217359,1.220090088,2.154864844,0.003242064,DB0031610039203_,5.731545151,0.478230545,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,11861,DB00497,10039203,82,19185,83,16292,0.273471458,0.838979937,0.610256923,1.153275207,0.4364551,DB0049710039203_,0.829069772,-0.175568486,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,11863,DB00695,10039203,75,27974,33,20495,0.014537819,1.665079757,1.091359735,2.590530546,0.048069283,DB0069510039203_,3.035111921,0.509873025,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,11865,DB00999,10039203,59,21371,24,12215,0.171482606,1.405093331,0.860197673,2.363199173,0.312819786,DB0099910039203_,1.162128018,0.340103729,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,11867,DB00497,10040047,234,19033,247,16128,0.018732602,0.802780177,0.667598697,0.965088234,0.058687299,DB0049710040047_,2.835531943,-0.219674354,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,oxycodone,DB00497
,11868,DB00863,10040047,119,10554,65,5775,1,1.001771008,0.732982691,1.379518301,1,DB0086310040047_,0,0.001769442,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ranitidine,DB00863
,11869,DB00999,10040047,180,21250,100,12139,0.851716833,1.028245074,0.799948643,1.32790372,0.927167107,DB0099910040047_,0.075621463,0.027853537,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,11870,DB01098,10040047,52,8097,75,7134,0.007187244,0.610899145,0.419817116,0.8831194,0.027346657,DB0109810040047_,3.599161,-0.492823399,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,rosuvastatin,DB01098
,11872,DB00316,10040872,68,65406,32,36921,0.465948693,1.199505954,0.776911442,1.887828447,0.632731197,DB0031610040872_,0.457709597,0.181909767,NA,10040872,Skin infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,11895,DB01129,10012735,60,852,33,403,0.49300875,0.860116132,0.543426153,1.381506377,0.655851033,DB0112910012735_,0.4218216,-0.150687862,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,rabeprazole,DB01129
,11896,DB01129,10013573,44,868,12,424,0.080688966,1.790396742,0.917634279,3.764078762,0.179508741,DB0112910013573_,1.717531373,0.582437239,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,rabeprazole,DB01129
,11898,DB01129,10019211,68,844,11,425,0.000170196,3.110786186,1.611848314,6.593649141,0.001258574,DB0112910019211_,6.677776144,1.134875487,female,10019211,Headache,10029205,Nervous system disorders,Nerv,rabeprazole,DB01129
,11906,DB00327,10003658,48,6090,44,4218,0.201333008,0.755606383,0.49036638,1.166787726,0.350605414,DB0032710003658_,1.048093866,-0.280234696,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,hydromorphone,DB00327
,11907,DB00813,10003658,58,10514,73,10095,0.136143249,0.762870307,0.530296032,1.093154925,0.264304671,DB0081310003658_,1.330652783,-0.27066724,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,fentanyl,DB00813
,11910,DB00327,10041349,117,6021,78,4184,0.82560025,1.042352569,0.773790496,1.410552355,0.907816628,DB0032710041349_,0.096712873,0.041480244,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,11911,DB00813,10041349,156,10416,107,10061,0.007494743,1.408225553,1.092282936,1.821276362,0.028278091,DB0081310041349_,3.565667955,0.342330439,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,11921,DB08877,10047943,80,3209,97,3132,0.170134282,0.804981225,0.588589713,1.098355586,0.311029323,DB0887710047943_,1.167868084,-0.216936325,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,ruxolitinib,DB08877
,11922,DB08877,10064355,37,3252,23,3206,0.09179076,1.585821273,0.915341393,2.802206547,0.198113079,DB0887710064355_,1.618917305,0.461102426,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,ruxolitinib,DB08877
,11923,DB06228,10018852,170,15742,203,15873,0.106674651,0.844412761,0.683804105,1.041695819,0.221148608,DB0622810018852_,1.508920369,-0.16911385,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,rivaroxaban,DB06228
,11930,DB00788,10068319,65,9291,26,5035,0.225389514,1.3547785,0.846415633,2.227838433,0.380213381,DB0078810068319_,0.967022655,0.303637972,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,naproxen,DB00788
,11931,DB01104,10068319,106,15357,30,7256,0.012572643,1.669423892,1.102862672,2.597212604,0.04273528,DB0110410068319_,3.152730462,0.512478592,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,11932,DB08895,10068319,431,27683,61,6585,8.12608346594741e-05,1.680658406,1.281124947,2.238357434,0.000668108,DB0889510068319_,7.311060832,0.519185625,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,11933,DB14726,10011906,52,1965,79,2769,0.719599676,0.927548435,0.637532296,1.339837946,0.834495609,DB1472610011906_,0.180927798,-0.075210265,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dabigatran,DB14726
,11939,DB00003,10018964,78,2920,71,2522,0.80287499,0.948834595,0.675925163,1.333826228,0.893342905,DB0000310018964_,0.11278478,-0.052520789,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dornase alfa,DB00003
,11940,DB00355,10018964,60,1733,45,1218,0.762861215,0.937124118,0.621419237,1.42185521,0.868699858,DB0035510018964_,0.140757602,-0.064939542,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,aztreonam,DB00355
,11941,DB00684,10018964,58,2734,61,2287,0.226946826,0.795403212,0.543027184,1.163958828,0.38211947,DB0068410018964_,0.96202197,-0.228906109,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tobramycin,DB00684
,11942,DB11065,10018964,45,3141,53,2635,0.102236637,0.712325555,0.466224618,1.084189344,0.214340179,DB1106510018964_,1.540190903,-0.339220232,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pancrelipase amylase,DB11065
,11943,DB00953,10013709,128,1569,11,221,0.136746889,1.638663906,0.867561224,3.419517521,0.26515137,DB0095310013709_,1.32745441,0.493881218,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,rizatriptan,DB00953
,11946,DB08907,10000081,56,4197,38,3872,0.147667016,1.359513437,0.882408049,2.114955524,0.28075425,DB0890710000081_,1.270275547,0.307126869,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,canagliflozin,DB08907
,11950,DB00482,10025482,255,8004,51,3020,1.5498426064655e-05,1.886466006,1.387478208,2.608804897,0.000159349,DB0048210025482_,8.744412785,0.63470524,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,11951,DB00999,10025482,749,20681,206,12033,1.80367602612633e-23,2.115472528,1.807619799,2.484296724,2.52178852908141e-21,DB0099910025482_,47.42931857,0.749278205,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,11952,DB00999,10033371,899,20531,309,11930,5.17795083306845e-16,1.690537594,1.480883117,1.933899889,3.58164309597906e-14,DB0099910033371_,30.96036964,0.525046581,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,11953,DB00207,10000059,110,8970,34,5421,0.000496103,1.955158264,1.318019732,2.967643719,0.003071864,DB0020710000059_,5.785470668,0.670471144,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,11954,DB00207,10028813,460,8620,170,5285,1.21284637058448e-08,1.658944711,1.383512772,1.996626388,2.68008968901328e-07,DB0020710028813_,15.13224539,0.506181684,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,11955,DB00207,10037844,313,8767,134,5321,0.000731823,1.417658768,1.150834422,1.754024306,0.004244945,DB0020710037844_,5.462026407,0.349006756,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,azithromycin,DB00207
,11956,DB00207,10047700,260,8820,109,5346,0.001287486,1.445761299,1.148506266,1.830028551,0.00677373,DB0020710047700_,4.994703317,0.368636033,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,11958,DB00864,10013709,198,6671,251,8141,0.700436518,0.962667972,0.792697045,1.167903845,0.819923573,DB0086410013709_,0.198544146,-0.038046712,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,11961,DB05679,10007882,31,6900,33,4876,0.126157113,0.663875985,0.392635229,1.119838196,0.250361625,DB0567910007882_,1.384848905,-0.409659916,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,ustekinumab,DB05679
,11962,DB00203,10007559,373,13505,188,8750,0.005756636,1.285463138,1.073586817,1.543311517,0.022907151,DB0020310007559_,3.776306156,0.251119072,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,sildenafil,DB00203
,11963,DB01240,10007559,100,5651,27,1549,1,1.015225537,0.655299398,1.622184667,1,DB0124010007559_,0,0.015110792,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,epoprostenol,DB01240
,11964,DB00203,10020919,493,13385,180,8758,7.4204904230291e-12,1.79204723,1.504506602,2.142248261,2.90033592222037e-10,DB0020310020919_,21.96102436,0.58335867,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,sildenafil,DB00203
,11965,DB00559,10020919,193,9466,59,3247,0.46630847,1.122061491,0.831773111,1.532926085,0.633093464,DB0055910020919_,0.457137215,0.115167611,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,bosentan,DB00559
,11966,DB01240,10020919,343,5408,102,1474,0.474968717,0.916547557,0.726888461,1.163557494,0.640583497,DB0124010020919_,0.445375805,-0.087141324,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,epoprostenol,DB01240
,11971,DB00203,10047461,109,13769,67,8871,0.816247289,1.048148903,0.765216988,1.444723935,0.901529928,DB0020310047461_,0.103662039,0.047025659,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,11972,DB00559,10047461,90,9569,53,3253,0.001975334,0.577304788,0.405670963,0.82862338,0.009634034,DB0055910047461_,4.642453254,-0.549384922,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,bosentan,DB00559
,11973,DB00682,10047461,92,19367,34,16330,2.08361728504998e-05,2.281454641,1.523285042,3.490030218,0.000206945,DB0068210047461_,8.48305958,0.82481324,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,11974,DB01240,10047461,48,5703,20,1556,0.136385997,0.654856079,0.380015611,1.168504651,0.264646827,DB0124010047461_,1.32935907,-0.423339795,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,11975,DB09053,10011906,208,2077,409,3643,0.216616589,0.891990316,0.744694457,1.066104118,0.36941329,DB0905310011906_,0.995839234,-0.114300003,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ibrutinib,DB09053
,11980,DB00068,10019211,109,2125,27,638,0.405468915,1.211978197,0.780910275,1.940301341,0.575115367,DB0006810019211_,0.55318462,0.192253898,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,interferon beta-1b,DB00068
,11981,DB08908,10019211,345,10328,76,3203,0.007173211,1.407759036,1.091517124,1.835144707,0.027307335,DB0890810019211_,3.600599921,0.341999104,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,11982,DB00068,10022052,125,2109,16,649,0.000442808,2.403390382,1.410457824,4.367443825,0.00279051,DB0006810022052_,5.881530796,0.8768804,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,11984,DB00068,10013573,65,2169,30,635,0.047034666,0.63442804,0.40157016,1.022617741,0.119513384,DB0006810013573_,2.124326913,-0.45503141,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,interferon beta-1b,DB00068
,11985,DB00068,10028813,78,2156,13,652,0.056309701,1.814065919,0.993393851,3.582180729,0.136654095,DB0006810028813_,1.9903024,0.59557069,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,interferon beta-1b,DB00068
,11989,DB00005,10024968,185,127897,82,42337,0.033257049,0.746824382,0.572664829,0.981083243,0.091828512,DB0000510024968_,2.387832438,-0.291925219,NA,10024968,Lower respiratory tract infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,11990,DB00313,10020575,21,1218,51,1466,0.007846824,0.495733448,0.281562769,0.844404459,0.029320319,DB0031310020575_,3.529474533,-0.701716901,NA,10020575,Hyperammonaemia,10027433,Metabolism and nutrition disorders,Metab,valproic acid,DB00313
,11995,DB00334,10020772,32,2817,41,2771,0.289871965,0.767781041,0.466521356,1.253503572,0.455072842,DB0033410020772_,0.787297781,-0.264250689,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,olanzapine,DB00334
,11997,DB00313,10022523,29,1210,30,1487,0.512088574,1.187883341,0.683776651,2.060860772,0.672340068,DB0031310022523_,0.396991013,0.172173019,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,valproic acid,DB00313
,11998,DB00334,10022523,32,2817,53,2759,0.021347365,0.591400406,0.367748525,0.937582034,0.065113488,DB0033410022523_,2.731623568,-0.525261984,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,olanzapine,DB00334
,12005,DB00313,10035664,26,1213,41,1476,0.322482062,0.771712929,0.450420791,1.300599293,0.490822434,DB0031310035664_,0.711672858,-0.259142651,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,valproic acid,DB00313
,12006,DB00334,10035664,76,2773,82,2730,0.573466448,0.912481499,0.655845496,1.268156781,0.723331142,DB0033410035664_,0.323888151,-0.091587469,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,olanzapine,DB00334
,12017,DB00046,10012671,113,5346,97,4595,1,1.001297701,0.754309029,1.331219046,1,DB0004610012671_,0,0.00129686,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,insulin lispro,DB00046
,12018,DB00046,10020635,59,5400,71,4621,0.062645868,0.711138491,0.493629759,1.021221915,0.148393335,DB0004610020635_,1.907888864,-0.340888084,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,insulin lispro,DB00046
,12025,DB01268,10038389,18,2125,45,3085,0.053129144,0.5807633,0.3154737,1.026787512,0.130880933,DB0126810038389_,2.03346728,-0.543412006,NA,10038389,Renal cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sunitinib,DB01268
,12029,DB00996,10061819,37,38916,14,22411,0.193105057,1.521961983,0.803421668,3.048371024,0.340529765,DB0099610061819_,1.077252742,0.420000281,NA,10061819,Disease recurrence,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,12031,DB00285,10013754,114,10837,40,3678,0.852458843,0.967269964,0.66783916,1.426580853,0.927744314,DB0028510013754_,0.074999108,-0.033277646,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,12041,DB00682,10030124,655,18804,337,16027,3.89197458299126e-14,1.656555526,1.447844503,1.898020111,2.10062734936192e-12,DB0068210030124_,26.88878508,0.504740462,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,12042,DB00820,10030124,509,11406,163,5653,9.02392734569425e-07,1.547625267,1.290932103,1.863170165,1.30865616707075e-05,DB0082010030124_,11.24392468,0.436721671,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,12043,DB01240,10030124,342,5409,94,1482,1,0.996849629,0.785127936,1.275451043,1,DB0124010030124_,0,-0.003155344,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,12045,DB00682,10062244,78,19381,22,16342,1.46494411927732e-06,2.989302724,1.841778113,5.04303055,2.01559747133968e-05,DB0068210062244_,10.8120098,1.095040157,female,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,12046,DB00820,10062244,67,11848,10,5806,0.0001247,3.283100686,1.677624302,7.164310099,0.000963477,DB0082010062244_,6.944962329,1.188788307,female,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,12047,DB01240,10062244,49,5702,8,1568,0.196650769,1.684185819,0.788889713,4.126502554,0.344931131,DB0124010062244_,1.064410502,0.521282253,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,12058,DB00421,10035226,39,8864,38,5214,0.032581459,0.603751574,0.375633461,0.971064986,0.090376072,DB0042110035226_,2.403775732,-0.504592467,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,spironolactone,DB00421
,12059,DB00437,10035226,105,6816,162,11384,0.525034285,1.082523236,0.83702557,1.395087809,0.683156046,DB0043710035226_,0.381031974,0.079294646,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,allopurinol,DB00437
,12061,DB00682,10035226,95,19364,151,16213,8.7401762458309e-07,0.526778728,0.402800925,0.686018588,1.272420562845e-05,DB0068210035226_,11.27200442,-0.64097469,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,warfarin,DB00682
,12062,DB00695,10035226,204,27845,245,20283,1.48889071772606e-07,0.606545227,0.500741009,0.734004298,2.60666352320596e-06,DB0069510035226_,12.8574395,-0.499975984,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,furosemide,DB00695
,12063,DB00722,10035226,110,25293,150,25882,0.02501341,0.75041697,0.580974024,0.966791009,0.073498124,DB0072210035226_,2.610495392,-0.287126267,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lisinopril,DB00722
,12064,DB00787,10035226,486,16514,595,16653,0.001792344,0.823687909,0.727724134,0.931967842,0.008889849,DB0078710035226_,4.722845166,-0.193963572,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acyclovir,DB00787
,12065,DB00904,10035226,248,22821,251,14205,8.82615759696261e-08,0.615044687,0.51327652,0.736909777,1.61669374519974e-06,DB0090410035226_,13.33512739,-0.486060351,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ondansetron,DB00904
,12066,DB00924,10035226,52,10110,38,4213,0.01040113,0.570285095,0.367547102,0.892027118,0.036729187,DB0092410035226_,3.304183544,-0.561618877,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyclobenzaprine,DB00924
,12067,DB01076,10035226,114,25633,188,25395,1.77602856219387e-05,0.600762534,0.471495574,0.762690645,0.000179826,DB0107610035226_,8.623519103,-0.509555541,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,atorvastatin,DB01076
,12086,DB00480,10003285,384,67044,353,67309,0.237365618,1.092098804,0.94230799,1.266051446,0.394756872,DB0048010003285_,0.929485218,0.088101353,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,12087,DB00480,10043607,1665,65763,1906,65756,7.19048442311313e-05,0.873465734,0.816661745,0.934128495,0.000600387,DB0048010043607_,7.417935817,-0.135286379,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,lenalidomide,DB00480
,12089,DB00472,10037377,50,10709,22,4290,0.696530636,0.910459634,0.540539947,1.580894762,0.817444647,DB0047210037377_,0.201572088,-0.093805715,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,12091,DB00472,10051055,31,10728,22,4290,0.046797539,0.563519674,0.315497598,1.022686927,0.119060477,DB0047210051055_,2.128123707,-0.573553032,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,fluoxetine,DB00472
,12092,DB01050,10051055,89,18019,57,9314,0.220490045,0.80711046,0.571772046,1.147240822,0.374053236,DB0105010051055_,0.983357148,-0.214294743,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,ibuprofen,DB01050
,12093,DB00005,10022111,289,127793,62,42357,0.001572566,1.544937481,1.17046485,2.067498745,0.007991071,DB0000510022111_,4.829430487,0.434983444,NA,10022111,Injection site vesicles,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,12095,DB00480,10005956,88,67340,104,67558,0.278778411,0.848895037,0.63158307,1.138826902,0.442634475,DB0048010005956_,0.815010962,-0.163819732,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,12096,DB00186,10002198,51,16850,15,9993,0.015068498,2.016341525,1.115327905,3.863380454,0.049503246,DB0018610002198_,3.00571703,0.701284743,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,lorazepam,DB00186
,12099,DB00338,10002198,100,33574,43,22229,0.016676733,1.53973085,1.066355804,2.256515176,0.053574668,DB0033810002198_,2.92667893,0.431607628,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,omeprazole,DB00338
,12100,DB01234,10002198,63,31562,60,32828,0.65234685,1.092101358,0.75430854,1.582623057,0.786610866,DB0123410002198_,0.240021605,0.088103692,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,dexamethasone,DB01234
,12102,DB00448,10013573,145,5000,70,3054,0.11700013,1.2651729,0.941224278,1.714127136,0.236614664,DB0044810013573_,1.44132235,0.235208793,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lansoprazole,DB00448
,12103,DB00448,10016173,107,5038,54,3070,0.28625709,1.207389445,0.859729322,1.712819544,0.451000546,DB0044810016173_,0.796286729,0.188460545,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,lansoprazole,DB00448
,12111,DB00005,10053156,264,127818,103,42316,0.164394074,0.848582961,0.673106206,1.076495482,0.303288172,DB0000510053156_,1.193071862,-0.164187425,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,12112,DB00005,10061368,88,127994,36,42383,0.298627341,0.809424535,0.54335147,1.228625698,0.46464141,DB0000510061368_,0.766489332,-0.211431735,NA,10061368,Spinal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,12113,DB00047,10012174,138,9147,127,8391,1,0.996805538,0.776123863,1.281068017,1,DB0004710012174_,0,-0.003199575,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,insulin glargine,DB00047
,12114,DB00215,10012174,126,10977,54,5222,0.574714656,1.110007107,0.799405984,1.559346827,0.724373112,DB0021510012174_,0.322448671,0.104366418,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,citalopram,DB00215
,12115,DB00331,10012174,372,24574,305,20447,0.876413609,1.014839022,0.86890284,1.186025021,0.947167391,DB0033110012174_,0.054279442,0.014730001,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,12116,DB00381,10012174,386,28974,275,22612,0.252947756,1.095459136,0.935040483,1.284651751,0.413311272,DB0038110012174_,0.883554284,0.091173577,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,12117,DB00480,10012174,1032,66396,897,66765,0.001547826,1.156893392,1.056167767,1.26740247,0.007892357,DB0048010012174_,4.841860421,0.145738302,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,12118,DB00588,10012174,207,16317,95,8373,0.392146897,1.118106671,0.871525929,1.443184998,0.562012005,DB0058810012174_,0.576232068,0.111636782,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,fluticasone propionate,DB00588
,12120,DB01076,10012174,333,25414,332,25251,0.968886529,0.996578914,0.852563497,1.164929126,1,DB0107610012174_,0,-0.003426951,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,12121,DB01234,10012174,587,31038,556,32332,0.113663786,1.099764674,0.976606723,1.238583629,0.231636891,DB0123410012174_,1.46258426,0.095096224,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,12122,DB00047,10020635,95,9190,97,8421,0.46831579,0.897434833,0.66802652,1.20537707,0.634820023,DB0004710020635_,0.454413749,-0.108214771,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,insulin glargine,DB00047
,12124,DB00331,10020635,121,24825,130,20622,0.042152397,0.77319416,0.598151183,0.998874005,0.109989155,DB0033110020635_,2.20737351,-0.257225085,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,12125,DB00381,10020635,59,29301,119,22768,7.27572984774787e-10,0.385259903,0.276926164,0.530985321,2.07421430637801e-08,DB0038110020635_,17.69109831,-0.953837101,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,12126,DB00480,10020635,33,67395,48,67614,0.119207868,0.689739158,0.428892827,1.097084744,0.240139206,DB0048010020635_,1.426536498,-0.371441785,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,12127,DB00588,10020635,35,16489,28,8440,0.083418514,0.639813503,0.377847238,1.092672655,0.184148453,DB0058810020635_,1.692013037,-0.446578547,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,fluticasone propionate,DB00588
,12129,DB00722,10020635,59,25344,76,25956,0.19661738,0.795067175,0.555788888,1.132506494,0.344890089,DB0072210020635_,1.064529495,-0.229328671,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,12131,DB01076,10020635,71,25676,74,25509,0.803274987,0.95320444,0.678165012,1.338979007,0.893490882,DB0107610020635_,0.112619149,-0.047925876,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,12132,DB01306,10020635,46,4162,47,3819,0.676488936,0.89807704,0.583408337,1.381742631,0.80384645,DB0130610020635_,0.21834701,-0.107499424,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,insulin aspart,DB01306
,12133,DB00047,10038435,105,9180,95,8423,0.943341579,1.014121523,0.759711488,1.355175317,0.982223193,DB0004710038435_,0.017936712,0.014022743,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,insulin glargine,DB00047
,12134,DB00215,10038435,65,11038,40,5236,0.208822219,0.77087934,0.511282773,1.174950164,0.359880149,DB0021510038435_,1.021984222,-0.260223416,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,citalopram,DB00215
,12135,DB00480,10038435,649,66779,862,66800,5.30928546870685e-08,0.753141108,0.678756603,0.835340171,1.02162934513147e-06,DB0048010038435_,13.79411181,-0.283502674,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,12137,DB00788,10038435,64,9292,42,5019,0.358038337,0.823096876,0.548219767,1.247280237,0.527761198,DB0078810038435_,0.639111373,-0.194681374,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,naproxen,DB00788
,12138,DB01076,10038435,251,25496,251,25332,0.964236426,0.993567415,0.830007874,1.189360791,1,DB0107610038435_,0,-0.006453363,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,12139,DB01234,10038435,292,31333,376,32512,0.006426769,0.805821618,0.688630366,0.942223445,0.025007791,DB0123410038435_,3.68856787,-0.215892879,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,dexamethasone,DB01234
,12140,DB01306,10038435,60,4148,54,3812,0.925086281,1.021107992,0.693138174,1.507350675,0.967854515,DB0130610038435_,0.032673498,0.020888304,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,insulin aspart,DB01306
,12143,DB00331,10063743,76,24870,52,20700,0.28730725,1.216473505,0.84331657,1.766761523,0.452180771,DB0033110063743_,0.793673243,0.195956103,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,12144,DB00381,10063743,70,29290,51,22836,0.783328246,1.070125461,0.735044199,1.567282566,0.88207274,DB0038110063743_,0.125480755,0.067775895,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,12145,DB00480,10063743,100,67328,102,67560,0.943905534,0.983768566,0.738927426,1.309487024,0.98267415,DB0048010063743_,0.017477699,-0.016364607,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,12146,DB00588,10063743,35,16489,15,8453,0.654519808,1.196140654,0.636112032,2.35880397,0.788308887,DB0058810063743_,0.237865278,0.179100252,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,fluticasone propionate,DB00588
,12148,DB00722,10063743,71,25332,60,25972,0.294034537,1.213222984,0.847787889,1.741220577,0.459781541,DB0072210063743_,0.777003813,0.193280441,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,12150,DB01076,10063743,72,25675,44,25539,0.011804662,1.627671076,1.102934775,2.426187474,0.040637227,DB0107610063743_,3.203070722,0.487150206,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,12151,DB01234,10063743,82,31543,86,32802,1,0.991545319,0.723363728,1.358315909,1,DB0123410063743_,0,-0.008490624,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,12155,DB00471,10001497,36,14153,22,5443,0.105086654,0.629333645,0.359959867,1.124076737,0.218675746,DB0047110001497_,1.520165257,-0.463093725,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,montelukast,DB00471
,12156,DB00588,10001497,36,16488,30,8438,0.05106743,0.614113337,0.36745439,1.033118388,0.127022229,DB0058810001497_,2.063393176,-0.48757578,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,12157,DB01050,10001497,62,18046,67,9304,3.478516055851e-05,0.477099187,0.331914579,0.684910735,0.000323198,DB0105010001497_,8.037244541,-0.740030871,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,12158,DB01050,10002855,469,17639,123,9248,8.52190866416626e-13,1.999086461,1.632978003,2.462433369,3.85539361854751e-11,DB0105010002855_,23.97896292,0.692690307,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,12159,DB00471,10012378,210,13979,66,5399,0.155540913,1.228863393,0.926009218,1.649044434,0.291497124,DB0047110012378_,1.23272514,0.206089672,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,montelukast,DB00471
,12160,DB00588,10012378,284,16240,105,8363,0.003528473,1.392834914,1.107843965,1.762200783,0.01542167,DB0058810012378_,4.171981597,0.331341176,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,12161,DB01050,10012378,417,17691,118,9253,9.74944899303452e-10,1.848311946,1.500787864,2.290645373,2.71466384302873e-08,DB0105010012378_,17.42201261,0.614272761,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,12164,DB01050,10022523,220,17888,106,9265,0.557365019,1.074982964,0.847596494,1.370398724,0.710479695,DB0105010022523_,0.34181491,0.072304814,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,12167,DB01050,10042464,126,17982,71,9300,0.597600092,0.917824053,0.680049257,1.247021285,0.742743855,DB0105010042464_,0.297404038,-0.08574957,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,12168,DB00864,10064355,33,6836,21,8371,0.019549064,1.924178684,1.079428699,3.502822462,0.060724078,DB0086410064355_,2.801414992,0.654499219,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,tacrolimus,DB00864
,12174,DB00982,10049414,40,3324,21,2080,0.597103907,1.191833244,0.683998886,2.134113351,0.742395301,DB0098210049414_,0.297873427,0.175492663,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,isotretinoin,DB00982
,12176,DB09053,10012735,137,2148,175,3877,0.003651504,1.41287171,1.114339809,1.788601878,0.015852637,DB0905310012735_,4.144419435,0.345624307,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ibrutinib,DB09053
,12177,DB09053,10016256,169,2116,222,3830,0.002752086,1.377777575,1.113190248,1.703037878,0.012600343,DB0905310016256_,4.374031242,0.320471748,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ibrutinib,DB09053
,12179,DB09053,10028334,55,2230,55,3997,0.002587593,1.792107141,1.205954421,2.663467674,0.011987113,DB0905310028334_,4.423923163,0.583392101,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ibrutinib,DB09053
,12182,DB09053,10061428,40,2245,68,3984,0.840199266,1.043861584,0.68564623,1.57098183,0.918252158,DB0905310061428_,0.085283244,0.042926899,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ibrutinib,DB09053
,12186,DB00999,10010305,194,21236,137,12102,0.058127743,0.80700272,0.644332666,1.012970872,0.139922866,DB0099910010305_,1.966663966,-0.21442824,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,12187,DB00999,10021036,164,21266,169,12070,8.2324471561788e-08,0.55081848,0.441033817,0.687691772,1.51586601401163e-06,DB0099910021036_,13.39952366,-0.596349962,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,12188,DB00215,10002855,303,10800,100,5176,0.001178497,1.452124605,1.151662838,1.843778823,0.006307146,DB0021510002855_,5.066071977,0.373027729,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,12190,DB00215,10061428,155,10948,79,5197,0.62207353,0.931376178,0.704316399,1.239837662,0.762258297,DB0021510061428_,0.271469809,-0.071092025,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,citalopram,DB00215
,12193,DB00285,10013573,375,10576,109,3609,0.151599252,1.173988326,0.942709749,1.471790917,0.286181151,DB0028510013573_,1.251130274,0.160406778,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,12194,DB00814,10013573,297,7990,109,3306,0.317272757,1.127405162,0.898675788,1.42278274,0.48510051,DB0081410013573_,0.723399172,0.119918676,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,12195,DB00285,10033557,99,10852,12,3706,0.000173103,2.817411504,1.54046121,5.643318416,0.001277199,DB0028510033557_,6.66308622,1.035818557,female,10033557,Palpitations,10007541,Cardiac disorders,Card,venlafaxine,DB00285
,12196,DB00814,10033557,62,8225,15,3400,0.060144324,1.708542796,0.958874214,3.238707462,0.143737198,DB0081410033557_,1.939768664,0.535640841,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,meloxicam,DB00814
,12199,DB00060,10000087,56,9452,8,2457,0.121718369,1.819506065,0.861242482,4.425897854,0.243874959,DB0006010000087_,1.41109965,0.598565071,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,interferon beta-1a,DB00060
,12200,DB00108,10000087,49,10145,13,3282,0.656617378,1.219358014,0.650438274,2.453198282,0.790020726,DB0010810000087_,0.235696099,0.198324502,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,natalizumab,DB00108
,12201,DB00060,10012735,133,9375,33,2432,0.922983259,1.045529202,0.707499873,1.585027103,0.966306952,DB0006010012735_,0.03427374,0.044523171,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,interferon beta-1a,DB00060
,12202,DB00060,10047942,72,9436,10,2455,0.073351755,1.873133011,0.960221615,4.077784352,0.167097186,DB0006010047942_,1.789179685,0.627612436,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,interferon beta-1a,DB00060
,12204,DB08908,10047942,209,10464,49,3230,0.088379378,1.316566465,0.957888264,1.840524828,0.192544712,DB0890810047942_,1.647426881,0.275027185,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,dimethyl fumarate,DB08908
,12206,DB08908,10056819,127,10546,41,3238,0.783753511,0.951061392,0.662405543,1.390779286,0.882287031,DB0890810056819_,0.125237844,-0.050176663,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,12207,DB00497,10001760,163,19104,49,16326,5.77435359611297e-12,2.842610351,2.052517008,3.999464609,2.30142356745761e-10,DB0049710001760_,22.19232306,1.044722768,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,12211,DB01373,10001760,360,22360,23,7358,6.18434437227324e-22,5.150568929,3.375274878,8.236021422,7.83399960603383e-20,DB0137310001760_,43.99322867,1.63910718,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,12213,DB00497,10003549,472,18795,401,15974,1,1.000407448,0.872351822,1.147638874,1,DB0049710003549_,0,0.000407365,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,12214,DB00868,10003549,91,2893,52,1594,0.859282257,0.964259954,0.674413307,1.391014215,0.933334743,DB0086810003549_,0.068991361,-0.036394359,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,benzonatate,DB00868
,12216,DB01043,10003549,68,1333,82,1328,0.275640566,0.826215273,0.58458856,1.164637622,0.438890978,DB0104310003549_,0.823504239,-0.190899918,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,memantine,DB01043
,12217,DB01373,10003549,672,22048,249,7132,0.07357939,0.873017589,0.751815347,1.016269986,0.16749236,DB0137310003549_,1.786817543,-0.135799576,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,12218,DB08865,10003549,32,1179,18,953,0.250768377,1.436764331,0.776914558,2.736742322,0.410579717,DB0886510003549_,0.890185173,0.362393593,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,crizotinib,DB08865
,12219,DB00497,10005557,82,19185,70,16305,1,0.995576801,0.714318874,1.39078135,1,DB0049710005557_,0,-0.00443301,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,oxycodone,DB00497
,12223,DB01373,10005557,119,22601,47,7334,0.277293169,0.821591775,0.580866585,1.178832206,0.44084138,DB0137310005557_,0.819070151,-0.196511631,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,calcium,DB01373
,12225,DB00868,10013573,105,2879,50,1596,0.395108797,1.164146141,0.818661622,1.674222636,0.564952771,DB0086810013573_,0.571013143,0.151987892,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,benzonatate,DB00868
,12227,DB01043,10013573,54,1347,53,1357,0.921699288,1.026427911,0.683961789,1.540852869,0.965406088,DB0104310013573_,0.03520645,0.026084727,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,memantine,DB01043
,12228,DB08865,10013573,55,1156,34,937,0.232764459,1.311027929,0.831761973,2.092571703,0.389263027,DB0886510013573_,0.943500001,0.270811508,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,crizotinib,DB08865
,12230,DB01043,10016256,90,1311,76,1334,0.262910919,1.204904097,0.869185173,1.673859031,0.424693554,DB0104310016256_,0.85638742,0.186399976,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,memantine,DB01043
,12231,DB00497,10017577,248,19019,146,16229,0.000364799,1.449430576,1.175337148,1.792662795,0.002374037,DB0049710017577_,6.043163503,0.371170773,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,12234,DB01043,10017577,34,1367,54,1356,0.039120815,0.624670404,0.391608736,0.98419965,0.103872713,DB0104310017577_,2.264589042,-0.470531122,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,memantine,DB01043
,12235,DB01373,10017577,372,22348,91,7290,0.014199383,1.333462881,1.055941615,1.698696054,0.047116177,DB0137310017577_,3.055138882,0.287779228,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,12236,DB00497,10024264,109,19158,112,16263,0.175598413,0.826157024,0.628201558,1.086132039,0.318098159,DB0049710024264_,1.145395268,-0.190970422,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,12243,DB01043,10041349,36,1365,51,1359,0.127046894,0.702870578,0.44250099,1.106143068,0.251497669,DB0104310041349_,1.380321557,-0.352582503,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,memantine,DB01043
,12244,DB01373,10041349,211,22509,65,7316,0.778596547,1.055057003,0.79436259,1.417515253,0.879325009,DB0137310041349_,0.128600702,0.053594797,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,calcium,DB01373
,12246,DB00497,10049438,40,19227,36,16339,0.818615692,0.94424743,0.586419615,1.52525391,0.90321487,DB0049710049438_,0.101794803,-0.05736704,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,12250,DB01373,10049438,43,22677,13,7368,1,1.074701798,0.566883409,2.179693741,1,DB0137310049438_,0,0.072043226,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,12252,DB00497,10049848,105,19162,70,16305,0.128170953,1.276344039,0.933607847,1.753909232,0.253077938,DB0049710049848_,1.374057783,0.243999771,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,12256,DB01373,10049848,183,22537,74,7307,0.109670053,0.801793177,0.608009609,1.066495102,0.225579259,DB0137310049848_,1.489083703,-0.220904588,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,calcium,DB01373
,12258,DB00497,10053762,456,18811,375,16000,0.647152771,1.034293307,0.898705772,1.190908855,0.782375614,DB0049710053762_,0.245420329,0.033718398,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,12259,DB00868,10053762,59,2925,34,1612,0.827594637,0.956362198,0.613814856,1.511299584,0.909305899,DB0086810053762_,0.095073719,-0.044618569,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,benzonatate,DB00868
,12261,DB01043,10053762,60,1341,55,1355,0.634789456,1.102255708,0.745448045,1.632575103,0.772957211,DB0104310053762_,0.257531586,0.097358724,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,memantine,DB01043
,12262,DB01373,10053762,3209,19511,332,7049,1.21932220646555e-130,3.491928509,3.107307699,3.934080515,3.77057461140554e-127,DB0137310053762_,291.1010794,1.250454165,female,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,12264,DB00497,10061428,343,18924,300,16075,0.719478423,0.971196695,0.828152772,1.139449488,0.834410216,DB0049710061428_,0.181030132,-0.029226262,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,12265,DB00868,10061428,60,2924,36,1610,0.668429793,0.917711486,0.594289693,1.435086587,0.798549091,DB0086810061428_,0.224958834,-0.085872223,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,benzonatate,DB00868
,12267,DB01043,10061428,44,1357,44,1366,1,1.006630271,0.64289062,1.576244088,1,DB0104310061428_,0,0.006608387,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,memantine,DB01043
,12268,DB01373,10061428,363,22357,158,7223,0.002405458,0.742263889,0.612892766,0.902215371,0.011311829,DB0137310061428_,4.481906324,-0.298050453,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,calcium,DB01373
,12269,DB08865,10061428,42,1169,31,940,0.810881587,1.089421988,0.662930772,1.807651616,0.898226748,DB0886510061428_,0.107332739,0.08564727,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,crizotinib,DB08865
,12278,DB00005,10015915,51,128031,13,42406,0.470659063,1.299374459,0.696477811,2.604619143,0.636922979,DB0000510015915_,0.451106543,0.261882964,NA,10015915,Eye discharge,10015919,Eye disorders,Eye,etanercept,DB00005
,12279,DB00005,10030041,172,127910,36,42383,0.010174903,1.583064243,1.099940808,2.335724956,0.036058384,DB0000510030041_,3.322615877,0.459362363,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,etanercept,DB00005
,12282,DB00868,10013700,125,2859,25,1621,3.35741063307634e-07,2.834365128,1.824590405,4.566541912,5.40910441252907e-06,DB0086810013700_,12.12742702,1.041817972,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,benzonatate,DB00868
,12283,DB01036,10013700,111,1390,10,412,5.87421643142924e-05,3.288789574,1.701993481,7.11485379,0.00050698,DB0103610013700_,7.587038942,1.190519586,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,tolterodine,DB01036
,12304,DB00704,10000081,34,4322,31,5163,0.317743016,1.310145418,0.779915824,2.208281379,0.485658846,DB0070410000081_,0.722248864,0.270138137,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,naltrexone,DB00704
,12305,DB00704,10012735,120,4236,124,5070,0.268654286,1.158254702,0.890486358,1.506130992,0.431079197,DB0070410012735_,0.841463455,0.146914305,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,naltrexone,DB00704
,12306,DB00704,10013754,29,4327,58,5136,0.022889975,0.593515608,0.365635645,0.944199836,0.068639895,DB0070410013754_,2.678881361,-0.521691768,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,12307,DB00704,10016256,294,4062,338,4856,0.64952486,1.039861024,0.881323538,1.226367369,0.784287431,DB0070410016256_,0.242979705,0.039087073,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,12308,DB00704,10020642,49,4307,72,5122,0.271227303,0.809353394,0.549866472,1.18264098,0.434027292,DB0070410020642_,0.834647863,-0.211519629,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,naltrexone,DB00704
,12311,DB00295,10028411,79,14584,37,9565,0.105321103,1.400321492,0.935399219,2.130886732,0.219073571,DB0029510028411_,1.518347667,0.336701847,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,12312,DB00704,10028411,58,4298,60,5134,0.457697658,1.15467272,0.788865199,1.689026256,0.624997815,DB0070410028411_,0.470007125,0.143816944,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,naltrexone,DB00704
,12313,DB00704,10028813,368,3988,349,4845,0.001576281,1.280993251,1.096764071,1.496401917,0.008003969,DB0070410028813_,4.827817706,0.247635754,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,naltrexone,DB00704
,12316,DB00704,10047700,140,4216,132,5062,0.055388725,1.273392285,0.993010833,1.633731113,0.134986106,DB0070410047700_,2.002583427,0.24168443,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,naltrexone,DB00704
,12317,DB00005,10022071,143,127939,7,42412,6.56082090648808e-11,6.77211448,3.202820708,17.1447061,2.20949618868724e-09,DB0000510022071_,19.93050132,1.912813369,female,10022071,Injection site hypersensitivity,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,12318,DB00005,10047571,641,127441,192,42227,0.228278091,1.106209163,0.939675556,1.307140178,0.383748377,DB0000510047571_,0.95776821,0.100939002,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,etanercept,DB00005
,12321,DB01222,10074170,36,9238,19,5386,0.780798369,1.104688724,0.616351265,2.040988763,0.880695395,DB0122210074170_,0.127043462,0.099563598,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,budesonide,DB01222
,12322,DB00158,10003549,390,16425,245,7859,0.001101582,0.761697752,0.646010725,0.899383088,0.005962127,DB0015810003549_,5.122327905,-0.272205453,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,12323,DB00231,10003549,124,3172,74,2065,0.604174593,1.090880094,0.806825821,1.483333447,0.747592288,DB0023110003549_,0.290897519,0.086984796,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,12324,DB00381,10003549,1005,28355,686,22201,0.006602089,1.147039727,1.038221805,1.267848364,0.025561337,DB0038110003549_,3.666674334,0.137184473,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,12325,DB00635,10003549,829,32224,600,23194,0.935075457,0.994487448,0.892993664,1.108039331,0.975328369,DB0063510003549_,0.024981076,-0.005527802,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,12326,DB00656,10003549,328,11685,187,6432,0.708930483,0.965526219,0.802173352,1.164796564,0.826298175,DB0065610003549_,0.190799584,-0.035082022,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,12327,DB00722,10003549,736,24667,690,25342,0.090635852,1.095843744,0.984891425,1.219348956,0.19622782,DB0072210003549_,1.628478947,0.091524609,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,12328,DB01104,10003549,424,15039,207,7079,0.665503466,0.964178587,0.812575442,1.146851799,0.796519299,DB0110410003549_,0.22750392,-0.036478745,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,12329,DB08895,10003549,347,27767,73,6573,0.382615846,1.125225853,0.870627868,1.471117943,0.552737429,DB0889510003549_,0.592872203,0.117983774,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,12330,DB10708,10003549,43,977,12,443,0.17978158,1.624301537,0.831433797,3.417959591,0.323613,DB1070810003549_,1.128206922,0.4850779,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,flax seed,DB10708
,12331,DB00231,10006451,44,3252,11,2128,0.003212926,2.617054279,1.326239598,5.631346641,0.014304316,DB0023110006451_,4.24719395,0.962049364,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,temazepam,DB00231
,12332,DB00327,10006451,40,6098,10,4252,0.002223052,2.78883348,1.368664211,6.261036829,0.010602963,DB0032710006451_,4.546621824,1.025623401,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,hydromorphone,DB00327
,12333,DB00451,10006451,567,46704,105,15314,1.56295583887318e-08,1.770532013,1.434214083,2.203618265,3.35639658699196e-07,DB0045110006451_,14.9072277,0.571280074,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,12334,DB00497,10006451,161,19106,45,16330,8.2603569458217e-13,3.057713198,2.183514775,4.359203394,3.74673826265614e-11,DB0049710006451_,24.00755036,1.117667316,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,oxycodone,DB00497
,12335,DB00656,10006451,124,11889,26,6593,1.17657931637641e-06,2.64463412,1.720002905,4.211881983,1.65381750432909e-05,DB0065610006451_,11.00983921,0.972532727,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,trazodone,DB00656
,12336,DB00722,10006451,239,25164,116,25916,8.44537252583498e-12,2.121873501,1.691543003,2.673908585,3.2645090711996e-10,DB0072210006451_,21.84274154,0.752299425,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,lisinopril,DB00722
,12337,DB00829,10006451,71,7981,13,4441,5.13920088137064e-05,3.038829643,1.666034469,5.991933303,0.000452391,DB0082910006451_,7.700964133,1.111472456,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,diazepam,DB00829
,12338,DB01104,10006451,137,15326,25,7261,1.74287901954081e-06,2.596168355,1.684491524,4.155924514,2.34630345857261e-05,DB0110410006451_,10.66008437,0.954036648,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,sertraline,DB01104
,12339,DB01222,10006451,242,9032,52,5353,6.40475824244507e-13,2.75801926,2.032372635,3.80463732,2.93802915187904e-11,DB0122210006451_,24.25069702,1.014512763,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,budesonide,DB01222
,12340,DB08895,10006451,460,27654,43,6603,4.79383623635578e-11,2.554291041,1.863861393,3.582177815,1.64713706500146e-09,DB0889510006451_,20.22422717,0.937774706,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,12342,DB00158,10010305,103,16712,76,8028,0.005046996,0.651032675,0.478753413,0.888661133,0.020617033,DB0015810010305_,3.881637714,-0.429195446,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,folic acid,DB00158
,12343,DB00231,10010305,44,3252,28,2111,1,1.020072782,0.618840922,1.707272879,1,DB0023110010305_,0,0.01987398,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,temazepam,DB00231
,12344,DB00381,10010305,322,29038,219,22668,0.127338019,1.147757709,0.962831404,1.370235934,0.251897328,DB0038110010305_,1.378733702,0.137810221,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,12345,DB00451,10010305,515,46756,190,15229,0.146758585,0.88286832,0.74531291,1.049305058,0.279411083,DB0045110010305_,1.275071164,-0.124579218,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,12346,DB00497,10010305,261,19006,238,16137,0.442048518,0.931114593,0.777056781,1.116110651,0.610162197,DB0049710010305_,0.49403046,-0.071372924,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,12347,DB00563,10010305,124,46522,80,15268,6.29144557674137e-06,0.508673051,0.380735236,0.682914428,7.24039610265529e-05,DB0056310010305_,9.53324955,-0.675949805,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,12348,DB00635,10010305,231,32822,224,23570,0.001612438,0.740570866,0.613058377,0.894702045,0.008148994,DB0063510010305_,4.809860736,-0.30033395,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,12349,DB00722,10010305,261,25142,255,25777,0.5956403,1.04939748,0.878845047,1.253081426,0.74122358,DB0072210010305_,0.299452972,0.048216171,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,12350,DB00829,10010305,107,7945,63,4391,0.68755176,0.938675122,0.679713385,1.305619508,0.811681829,DB0082910010305_,0.208646852,-0.063285842,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,12351,DB01222,10010305,64,9210,51,5354,0.099157608,0.729543034,0.496265077,1.077252988,0.209573251,DB0122210010305_,1.562681956,-0.315336922,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,budesonide,DB01222
,12352,DB08895,10010305,75,28039,13,6633,0.343622871,1.364772685,0.751165524,2.683140197,0.512893885,DB0889510010305_,0.667686306,0.310987883,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,tofacitinib,DB08895
,12354,DB00231,10012735,206,3090,95,2044,0.004301521,1.434293139,1.111835077,1.861080632,0.018120922,DB0023110012735_,4.010688118,0.360672142,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,temazepam,DB00231
,12355,DB00264,10012735,1841,27766,1248,23644,1.3029180695738e-09,1.256158442,1.16594462,1.353621624,3.53976242467672e-08,DB0026410012735_,17.15662113,0.228058208,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,12356,DB00327,10012735,284,5854,158,4104,0.022964196,1.260103417,1.029302676,1.547017086,0.068823203,DB0032710012735_,2.676214339,0.231193795,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,hydromorphone,DB00327
,12357,DB00563,10012735,1249,45397,431,14917,0.390003206,0.952222037,0.851408407,1.066589222,0.559916665,DB0056310012735_,0.579967318,-0.048957039,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,12358,DB00635,10012735,1662,31391,945,22849,2.23701073618414e-09,1.280144701,1.178989447,1.390618114,5.78169392336284e-08,DB0063510012735_,16.66598404,0.246973119,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,12359,DB00656,10012735,596,11417,271,6348,0.007147555,1.222764434,1.05386972,1.421593815,0.027237911,DB0065610012735_,3.603145495,0.201114225,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,12360,DB00722,10012735,1547,23856,1140,24892,2.83425574317502e-18,1.415930576,1.308079701,1.53303223,2.50414830955817e-16,DB0072210012735_,35.92341281,0.347786966,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,12361,DB01222,10012735,430,8844,214,5191,0.05464797,1.179417913,0.995008058,1.40118459,0.133732604,DB0122210012735_,2.011912965,0.165021023,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,12362,DB10708,10012735,71,949,32,423,1,0.988975982,0.631794082,1.57704866,1,DB1070810012735_,0,-0.011085233,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,flax seed,DB10708
,12363,DB00158,10013952,66,16749,16,8088,0.012628662,1.991891439,1.139715715,3.687976768,0.042884101,DB0015810013952_,3.149254128,0.689084659,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,12365,DB00264,10013952,107,29500,71,24821,0.131726386,1.268003166,0.930166539,1.73759479,0.258207096,DB0026410013952_,1.353993318,0.237443353,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,12367,DB00338,10013952,191,33483,83,22189,0.00125712,1.524983534,1.171888227,1.999106065,0.006639159,DB0033810013952_,5.014770009,0.421983612,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,12368,DB00381,10013952,148,29212,74,22813,0.001759825,1.561876684,1.173099917,2.094776703,0.008752507,DB0038110013952_,4.738415134,0.445888101,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,12369,DB00451,10013952,263,47008,79,15340,0.570964823,1.08637931,0.841222028,1.416308894,0.721390616,DB0045110013952_,0.326574519,0.082850433,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,12370,DB00497,10013952,62,19205,42,16333,0.278939021,1.255425212,0.834542305,1.905181747,0.442812459,DB0049710013952_,0.814608941,0.227474329,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,12371,DB00563,10013952,84,46562,13,15335,0.009115072,2.127924935,1.179127505,4.163404553,0.033065092,DB0056310013952_,3.40927717,0.755147296,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,12372,DB00635,10013952,148,32905,49,23745,7.07485265773073e-07,2.17954992,1.567269882,3.076801518,1.05480715886813e-05,DB0063510013952_,11.4595675,0.779118397,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,12373,DB00656,10013952,41,11972,15,6604,0.208110758,1.507731212,0.816334585,2.934762725,0.358936436,DB0065610013952_,1.024609966,0.410606012,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,12374,DB00695,10013952,144,27905,54,20474,1.35690380847009e-05,1.956504608,1.420915337,2.728723562,0.000142012,DB0069510013952_,8.859601722,0.671159518,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,12375,DB00722,10013952,88,25315,99,25933,0.557998413,0.910605101,0.675055432,1.226615226,0.710996397,DB0072210013952_,0.341087917,-0.093645954,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,12377,DB01104,10013952,49,15414,14,7272,0.105105674,1.651193105,0.896381977,3.240757294,0.21870667,DB0110410013952_,1.520023855,0.50149812,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,12378,DB01222,10013952,64,9210,34,5371,0.752736635,1.097738455,0.712239827,1.718861362,0.860733565,DB0122210013952_,0.149970271,0.093252113,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,12379,DB08895,10013952,90,28024,7,6639,0.001691325,3.045868358,1.418312632,7.79582022,0.008469541,DB0889510013952_,4.771278999,1.113786036,female,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,12381,DB00158,10021036,40,16775,20,8084,0.89081034,0.963835221,0.549910081,1.741348258,0.954680373,DB0015810021036_,0.046378682,-0.036834932,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,folic acid,DB00158
,12383,DB00264,10021036,116,29491,81,24811,0.223147306,1.204830555,0.898877706,1.621469284,0.377404171,DB0026410021036_,0.974438594,0.186338939,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,12385,DB00338,10021036,107,33567,85,22187,0.209947108,0.832061193,0.619671805,1.120166288,0.361084848,DB0033810021036_,1.018642312,-0.183849291,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,12386,DB00381,10021036,112,29248,76,22811,0.377147552,1.149328855,0.850831323,1.559769307,0.547062713,DB0038110021036_,0.603191835,0.139178167,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,12387,DB00451,10021036,186,47085,93,15326,0.001019128,0.65099813,0.504514799,0.844859543,0.005590687,DB0045110021036_,5.186653138,-0.429248509,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,12388,DB00497,10021036,78,19189,75,16300,0.464925334,0.883426826,0.634653122,1.230406177,0.631782164,DB0049710021036_,0.459210621,-0.123946813,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,12389,DB00563,10021036,31,46615,54,15294,4.67374847611581e-14,0.188354522,0.117029071,0.298407864,2.48683155252437e-12,DB0056310021036_,26.72001168,-1.669429335,male,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,12390,DB00635,10021036,87,32966,103,23691,0.000669472,0.607034009,0.450778883,0.815879144,0.003949514,DB0063510021036_,5.534162764,-0.499170461,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,12391,DB00656,10021036,34,11979,39,6580,0.001995274,0.478882503,0.292959093,0.779448264,0.009703624,DB0065610021036_,4.635255839,-0.736300009,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,trazodone,DB00656
,12392,DB00695,10021036,150,27899,124,20404,0.326704999,0.884704299,0.692255833,1.132334193,0.495110317,DB0069510021036_,0.702974679,-0.122501815,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,12394,DB01104,10021036,44,15419,34,7252,0.037921462,0.608667484,0.379915833,0.982870856,0.101482959,DB0110410021036_,2.287864382,-0.496483164,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,sertraline,DB01104
,12398,DB00231,10037660,85,3211,45,2094,0.276732562,1.231745611,0.844557793,1.817376986,0.440189743,DB0023110037660_,0.820549411,0.20843236,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,12399,DB00381,10037660,469,28891,399,22488,0.201878982,0.914932861,0.797952434,1.0494545,0.35126488,DB0038110037660_,1.046214695,-0.088904592,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,12400,DB00656,10037660,198,11815,121,6498,0.376285265,0.899973268,0.71267479,1.140310335,0.54608316,DB0065610037660_,0.604984006,-0.105390219,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,12401,DB00722,10037660,337,25066,370,25662,0.363534046,0.93243987,0.801275634,1.08485264,0.533096734,DB0072210037660_,0.629052382,-0.069950612,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,12402,DB01104,10037660,243,15220,117,7169,0.864411216,0.978267355,0.780012142,1.232695293,0.937820609,DB0110410037660_,0.064196596,-0.021972277,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,12403,DB01222,10037660,213,9061,159,5246,0.019104859,0.775623886,0.626742453,0.961353233,0.059608283,DB0122210037660_,2.819960744,-0.254087559,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,12404,DB08895,10037660,395,27719,84,6562,0.412674575,1.113204751,0.876144145,1.428407485,0.58210047,DB0889510037660_,0.541112217,0.107243019,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,12406,DB00158,10068319,170,16645,31,8073,5.34815122986486e-08,2.65964661,1.80395227,4.040515058,1.02835519441842e-06,DB0015810068319_,13.78754993,0.978193261,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,12408,DB00264,10068319,169,29438,69,24823,1.46048897845408e-07,2.065234013,1.551237694,2.775212503,2.56011689220843e-06,DB0026410068319_,12.87545764,0.725243543,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,12410,DB00338,10068319,277,33397,84,22188,3.08015157913525e-11,2.190804137,1.709316724,2.832858828,1.09112916789178e-09,DB0033810068319_,20.63605274,0.784268662,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,12411,DB00381,10068319,186,29174,83,22804,1.4737048604005e-05,1.751631545,1.344428007,2.298558815,0.000152646,DB0038110068319_,8.787387364,0.560547665,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,12412,DB00497,10068319,94,19173,49,16326,0.005384532,1.633482368,1.143769912,2.358377823,0.021701931,DB0049710068319_,3.830354039,0.490714158,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,12413,DB00563,10068319,265,46381,61,15287,0.010060446,1.431816569,1.079612263,1.925070544,0.035738033,DB0056310068319_,3.331539814,0.358943966,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,12414,DB00635,10068319,297,32756,91,23703,3.44881105688738e-14,2.361657965,1.860199999,3.02272579,1.882699867711e-12,DB0063510068319_,26.99831427,0.8593639,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,12415,DB00656,10068319,64,11949,14,6605,0.000821806,2.526821061,1.40063785,4.883595711,0.004682675,DB0065610068319_,5.36388567,0.926962015,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,12416,DB00695,10068319,224,27825,76,20452,1.08996424184371e-09,2.166329495,1.661838299,2.850364343,3.00311426591845e-08,DB0069510068319_,17.32103091,0.773034258,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,12417,DB00722,10068319,138,25265,85,25947,0.000208773,1.66732682,1.262611953,2.212401613,0.00149363,DB0072210068319_,6.506546128,0.511221638,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,12418,DB00829,10068319,43,8009,11,4443,0.021816745,2.168452875,1.098253161,4.668030017,0.066203319,DB0082910068319_,2.715024676,0.774013952,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diazepam,DB00829
,12419,DB01222,10068319,104,9170,29,5376,0.000270802,2.102350364,1.379374281,3.296491021,0.001855584,DB0122210068319_,6.289555824,0.74305594,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,12421,DB00169,10002855,724,37967,188,17987,1.76007211371417e-14,1.824437433,1.550299303,2.15566171,9.99211566068616e-13,DB0016910002855_,27.63180986,0.601271684,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,12422,DB00316,10002855,1220,64254,375,36578,1.66049718350791e-27,1.852019192,1.647041063,2.086340396,3.10648885896836e-25,DB0031610002855_,56.43113422,0.616276499,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,12423,DB00332,10002855,60,2624,18,1638,0.006441203,2.080473184,1.206564467,3.758016041,0.025052829,DB0033210002855_,3.686768509,0.73259536,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ipratropium,DB00332
,12424,DB00338,10002855,578,33096,208,22064,3.64329899874106e-15,1.852539257,1.576826091,2.183213872,2.27738678197167e-13,DB0033810002855_,29.11057757,0.61655727,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,12425,DB00404,10002855,725,19167,235,9627,3.47509742839937e-09,1.549533479,1.332866931,1.80657149,8.64580557553027e-08,DB0040410002855_,16.26360645,0.437953905,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,12426,DB00863,10002855,199,10474,83,5757,0.0380292,1.31780882,1.012905628,1.727248788,0.101678111,DB0086310002855_,2.285943226,0.275970372,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ranitidine,DB00863
,12427,DB00904,10002855,615,22454,164,14292,5.74613298381343e-26,2.386818994,2.003181372,2.856601363,9.46941100185179e-24,DB0090410002855_,53.01397552,0.869961515,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,12431,DB13961,10002855,169,9288,74,6340,0.00151599,1.55887009,1.177034982,2.081448071,0.007760795,DB1396110002855_,4.85867056,0.443961257,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,fish oil,DB13961
,12434,DB00863,10012378,206,10467,57,5783,1.74658910429768e-06,1.996672092,1.47965894,2.731620879,2.35009442572124e-05,DB0086310012378_,10.65846996,0.691481841,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ranitidine,DB00863
,12438,DB13961,10012378,186,9271,91,6323,0.009466475,1.393988093,1.07676225,1.815289186,0.034067126,DB1396110012378_,3.379422413,0.33216877,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,fish oil,DB13961
,12440,DB00169,10013496,102,38589,43,18132,0.59331355,1.11458082,0.772863498,1.63186628,0.7393565,DB0016910013496_,0.301975066,0.108478388,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,12441,DB00182,10013496,80,5114,47,2805,0.709220441,0.933616317,0.641178542,1.372721289,0.826468108,DB0018210013496_,0.19059395,-0.068689721,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,12442,DB00316,10013496,143,65331,60,36893,0.057012197,1.345885809,0.98864652,1.851703655,0.137799135,DB0031610013496_,1.981958196,0.29705239,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,12444,DB00338,10013496,87,33587,30,22242,0.001698393,1.920412902,1.254648813,3.014523729,0.008499241,DB0033810013496_,4.767778419,0.652540216,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,12445,DB00404,10013496,79,19813,24,9838,0.035690643,1.634428121,1.023139079,2.701498222,0.096859072,DB0040410013496_,2.334498222,0.49129297,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,12448,DB00904,10013496,49,23020,18,14438,0.058800799,1.707336065,0.976576538,3.115460631,0.141228878,DB0090410013496_,1.957373456,0.534934299,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,12450,DB01104,10013496,53,15410,26,7260,0.903951615,0.960375731,0.589420444,1.601318471,0.957442354,DB0110410013496_,0.043489764,-0.040430685,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,12451,DB01224,10013496,40,8068,22,5895,0.304958724,1.328453434,0.769839849,2.349708192,0.471767788,DB0122410013496_,0.751268389,0.284015434,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,12456,DB00169,10013700,476,38215,128,18047,4.53510812732297e-09,1.756160499,1.44067381,2.153431394,1.10018751385957e-07,DB0016910013700_,16.02261502,0.563129892,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,cholecalciferol,DB00169
,12457,DB00182,10013700,49,5145,14,2838,0.033476214,1.930470438,1.046596648,3.793461809,0.092302769,DB0018210013700_,2.382681141,0.657763724,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,amphetamine,DB00182
,12458,DB00332,10013700,60,2624,16,1640,0.001787148,2.343340461,1.327039092,4.374166939,0.008867425,DB0033210013700_,4.725370851,0.851577459,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ipratropium,DB00332
,12459,DB00863,10013700,234,10439,57,5783,4.26006814389134e-09,2.274133691,1.692617231,3.099130018,1.03873739482545e-07,DB0086310013700_,16.08008972,0.821599185,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ranitidine,DB00863
,12460,DB00904,10013700,338,22731,94,14362,1.01384606105088e-13,2.271826256,1.800769416,2.889312207,5.17958089693342e-12,DB0090410013700_,25.98629697,0.820584026,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ondansetron,DB00904
,12516,DB00169,10044565,431,38260,173,18002,0.079467044,1.172198528,0.979470383,1.407866956,0.177535272,DB0016910044565_,1.728585974,0.15888107,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,12517,DB00182,10044565,101,5093,20,2832,5.06500317520353e-06,2.807783951,1.721287302,4.801783817,5.99296009274025e-05,DB0018210044565_,9.722340002,1.032395543,female,10044565,Tremor,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,12518,DB00316,10044565,636,64838,330,36623,0.225594832,1.088606787,0.950944472,1.247997572,0.380381048,DB0031610044565_,0.96658177,0.084898702,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,12520,DB00338,10044565,368,33306,192,22080,0.007136078,1.270632773,1.063411346,1.522175462,0.027210311,DB0033810044565_,3.604159291,0.239515023,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,12521,DB00404,10044565,299,19593,106,9756,0.002430478,1.40453151,1.120178221,1.772325642,0.011405151,DB0040410044565_,4.473690197,0.339703802,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,12522,DB00413,10044565,50,2149,31,1176,0.638398629,0.882668156,0.54946687,1.438019104,0.775609335,DB0041310044565_,0.254106319,-0.124805963,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,pramipexole,DB00413
,12523,DB00863,10044565,105,10568,58,5782,1,0.990480079,0.710845201,1.39186815,1,DB0086310044565_,0,-0.009565525,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,12524,DB00904,10044565,225,22844,114,14342,0.06441021,1.239091861,0.983814649,1.567825992,0.151385735,DB0090410044565_,1.887924165,0.214378741,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,12526,DB01104,10044565,246,15217,128,7158,0.371361873,0.904048125,0.72583632,1.130395443,0.541008758,DB0110410044565_,0.614319811,-0.100872685,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,12527,DB01224,10044565,147,7961,84,5833,0.080516347,1.282196477,0.971881277,1.700784076,0.179277609,DB0122410044565_,1.718819789,0.248574605,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,12530,DB13961,10044565,101,9356,59,6355,0.374214334,1.162727232,0.833736928,1.63422615,0.544053971,DB1396110044565_,0.608706826,0.150768308,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,12531,DB14509,10044565,40,845,26,525,0.897159886,0.955900777,0.561605192,1.652178294,0.956338178,DB1450910044565_,0.044643686,-0.045101161,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,lithium carbonate,DB14509
,12532,DB00169,10048439,114,38577,8,18167,1.58100840722853e-11,6.710862647,3.291984146,15.91841957,5.82435963335695e-10,DB0016910048439_,21.26380187,1.903727504,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,12534,DB00316,10048439,189,65285,15,36938,1.81377442942712e-21,7.129533746,4.213163116,12.99210807,2.19320790551296e-19,DB0031610048439_,42.9637515,1.964245839,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,12536,DB00338,10048439,116,33558,8,22264,3.44095021474517e-17,9.620580426,4.721642512,22.81483172,2.71607736920651e-15,DB0033810048439_,33.5395877,2.263904598,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,12537,DB00404,10048439,88,19804,6,9856,7.7944539679093e-10,7.299288268,3.221321865,20.43177922,2.21130299564486e-08,DB0040410048439_,17.62709881,1.987776846,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,12549,DB01101,10003549,198,7391,96,3812,0.662574675,1.063758759,0.826746221,1.376403791,0.794279768,DB0110110003549_,0.230319527,0.061808635,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,12550,DB01101,10061428,227,7362,107,3801,0.48184506,1.095328626,0.863555704,1.396359577,0.646313885,DB0110110061428_,0.436470004,0.091054433,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,capecitabine,DB01101
,12551,DB00295,10046735,237,14426,66,9536,4.73731373497807e-11,2.373605334,1.797484723,3.171421767,1.6309140998546e-09,DB0029510046735_,20.23412518,0.864410037,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,morphine,DB00295
,12552,DB00443,10013709,143,2003,69,1121,0.336618041,1.159859324,0.855707295,1.584189787,0.505667832,DB0044310013709_,0.681875284,0.148298726,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,betamethasone,DB00443
,12553,DB00798,10013709,45,762,47,597,0.194015485,0.750283195,0.480036588,1.171356366,0.341725927,DB0079810013709_,1.073746247,-0.287304551,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,gentamicin,DB00798
,12554,DB01190,10013709,170,4764,111,2174,0.004829215,0.698921561,0.543920832,0.90096631,0.01991308,DB0119010013709_,3.916378469,-0.358216759,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,clindamycin,DB01190
,12564,DB01267,10005780,205,2647,103,3612,8.12566624213003e-17,2.715473329,2.120835703,3.493924613,6.10237534783965e-15,DB0126710005780_,32.7300983,0.998966277,NA,10005780,Blood prolactin increased,10022891,Investigations,Inv,paliperidone,DB01267
,12566,DB01267,10047899,140,2712,171,3544,0.59794104,1.069863885,0.844605877,1.353474853,0.742956829,DB0126710047899_,0.297117339,0.06753143,NA,10047899,Weight increased,10022891,Investigations,Inv,paliperidone,DB01267
,12567,DB00555,10013709,376,6671,175,3311,0.515189547,1.066393359,0.884457995,1.289558815,0.675029023,DB0055510013709_,0.392999592,0.064282262,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,12568,DB01202,10013709,513,6201,468,5250,0.270770573,0.928057353,0.812716142,1.059925147,0.43347369,DB0120210013709_,0.835924176,-0.074661746,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,12572,DB00736,10013573,345,10246,143,5410,0.017647706,1.273884651,1.042198218,1.563554814,0.05603309,DB0073610013573_,2.881812862,0.242071012,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,12573,DB00950,10013573,160,4558,51,2005,0.048054695,1.380008278,0.996276813,1.939041073,0.121447731,DB0095010013573_,2.108271308,0.322089498,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,fexofenadine,DB00950
,12574,DB00182,10028813,320,4874,89,2763,8.35281868411386e-10,2.038074587,1.598698568,2.620044792,2.35952540689879e-08,DB0018210028813_,17.56222024,0.712005532,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,amphetamine,DB00182
,12575,DB00279,10028813,105,1132,8,208,0.012877827,2.410598937,1.155591268,5.817174309,0.043536165,DB0027910028813_,3.134163298,0.879875238,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,liothyronine,DB00279
,12576,DB00335,10028813,570,7896,202,5263,5.27522719686244e-15,1.880742021,1.592789083,2.227735353,3.22089075190544e-13,DB0033510028813_,28.76394826,0.631666391,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,12577,DB00736,10028813,744,9847,236,5317,7.15686632991966e-13,1.702198076,1.462586362,1.986692346,3.26594151878365e-11,DB0073610028813_,24.14488793,0.531920402,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,12578,DB00950,10028813,316,4402,69,1987,1.31238675377671e-08,2.067023375,1.579305203,2.737440056,2.86869736573977e-07,DB0095010028813_,15.0642376,0.726109589,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fexofenadine,DB00950
,12579,DB00480,10013573,1321,66107,1135,66527,0.000108593,1.171268513,1.080330132,1.269983907,0.000855753,DB0048010013573_,7.063529281,0.158087361,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,12580,DB00480,10061225,111,67317,119,67543,0.644319645,0.935878178,0.71587472,1.222781602,0.780474911,DB0048010061225_,0.247852684,-0.066269962,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,12582,DB00051,10043607,69,25662,48,11372,0.020525827,0.637030072,0.434097792,0.941552309,0.063087156,DB0005110043607_,2.763238083,-0.450938415,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,adalimumab,DB00051
,12584,DB01042,10070863,62,928,62,1266,0.093864222,1.364019714,0.93349724,1.993166199,0.201549813,DB0104210070863_,1.601718716,0.310436012,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,melphalan,DB01042
,12585,DB00557,10013700,325,5662,66,3001,2.34402322565169e-14,2.609725214,1.989514886,3.467108573,1.31090745715435e-12,DB0055710013700_,27.3603015,0.959244934,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,hydroxyzine,DB00557
,12586,DB00005,10003402,35,128047,18,42401,0.151062578,0.643878147,0.354874293,1.207743865,0.285362742,DB0000510003402_,1.25399413,-0.440245783,NA,10003402,Arthropod sting,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,12587,DB00252,10013700,414,1818,143,1765,3.06658973468827e-26,2.810046732,2.29105226,3.461725991,5.16700712668469e-24,DB0025210013700_,53.6197486,1.033201114,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,phenytoin,DB00252
,12588,DB00564,10013700,220,2384,43,1420,5.41043425330362e-13,3.046719129,2.173044391,4.358557452,2.50375465401559e-11,DB0056410013700_,24.41064456,1.114065316,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,carbamazepine,DB00564
,12589,DB00019,10011906,429,18583,376,9153,2.1212690018355e-15,0.561958557,0.487042674,0.648679063,1.3666067576776e-13,DB0001910011906_,29.62127536,-0.576327174,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,12593,DB00319,10010305,21,1371,33,1820,0.581850354,0.844818215,0.462280436,1.511959008,0.730073111,DB0031910010305_,0.314610598,-0.168633806,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,piperacillin,DB00319
,12595,DB00480,10010305,428,67000,393,67269,0.207646654,1.093412631,0.95083843,1.257644746,0.358441736,DB0048010010305_,1.025989155,0.089303659,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,12596,DB00706,10010305,13,1062,273,15652,0.268500064,0.701813621,0.367662684,1.225876161,0.430942554,DB0070610010305_,0.841780483,-0.354087407,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,tamsulosin,DB00706
,12597,DB00787,10010305,183,16817,185,17063,1,1.003659105,0.812724963,1.239382155,1,DB0078710010305_,0,0.003652427,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,acyclovir,DB00787
,12598,DB01015,10010305,87,9800,104,9277,0.110183922,0.791906544,0.587838537,1.064621533,0.226317448,DB0101510010305_,1.485816627,-0.233311894,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,sulfamethoxazole,DB01015
,12599,DB01234,10010305,321,31304,324,32564,0.721725643,1.030625621,0.879709404,1.207340979,0.836020471,DB0123410010305_,0.179102179,0.030166017,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,12600,DB08889,10010305,29,3136,40,3845,0.715540621,0.888944845,0.530203042,1.473881442,0.831586206,DB0888910010305_,0.18442031,-0.117720087,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,carfilzomib,DB08889
,12602,DB14512,10028735,67,4777,28,2384,0.510788679,1.19412497,0.755335943,1.933784859,0.671136238,DB1451210028735_,0.398783126,0.177413675,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mometasone furoate,DB14512
,12609,DB04844,10011906,148,528,92,377,0.375984397,1.148494445,0.849924943,1.557256964,0.545751989,DB0484410011906_,0.60559064,0.138451906,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tetrabenazine,DB04844
,12613,DB00480,10044034,494,66934,439,67223,0.065773432,1.130141709,0.991307371,1.288733574,0.153751049,DB0048010044034_,1.872420551,0.122343031,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,12622,DB00152,10016173,38,793,33,831,0.468273218,1.20655884,0.728746556,2.006770081,0.634789146,DB0015210016173_,0.454462389,0.187772374,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,thiamine,DB00152
,12623,DB00153,10016173,224,7199,100,3339,0.808408761,1.038926065,0.814051335,1.33353523,0.896602219,DB0015310016173_,0.109142972,0.03818755,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ergocalciferol,DB00153
,12624,DB00227,10016173,88,2379,54,1749,0.341967168,1.198025323,0.839044807,1.723884141,0.511195553,DB0022710016173_,0.671003076,0.180674637,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,lovastatin,DB00227
,12625,DB00455,10016173,228,9173,133,4985,0.53955298,0.931621668,0.746805931,1.165958588,0.695339776,DB0045510016173_,0.363354666,-0.070828483,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,12626,DB00722,10016173,751,24652,574,25458,7.4702502855598e-08,1.351125508,1.20865051,1.511029734,1.38963573075683e-06,DB0072210016173_,13.48646891,0.300937955,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,12627,DB01118,10016173,114,2949,147,4562,0.156590777,1.199650054,0.926739755,1.549751548,0.292848707,DB0111810016173_,1.228099163,0.182029893,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,amiodarone,DB01118
,12629,DB00153,10030124,87,7336,38,3401,0.846709149,1.061403037,0.715449804,1.601129977,0.922998542,DB0015310030124_,0.080127624,0.059591653,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,12630,DB00227,10030124,32,2435,23,1780,1,1.017048997,0.574621733,1.82684861,1,DB0022710030124_,0,0.016905294,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,lovastatin,DB00227
,12631,DB00761,10030124,423,14884,228,8397,0.619491369,1.046671908,0.886836975,1.237821313,0.760228331,DB0076110030124_,0.274136455,0.045615519,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,12632,DB01118,10030124,59,3004,64,4645,0.06241097,1.425367187,0.980376222,2.069426676,0.147954477,DB0111810030124_,1.910850639,0.354429456,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,12633,DB06605,10030124,217,13856,146,12887,0.002556247,1.38233842,1.113977465,1.719330745,0.011868046,DB0660510030124_,4.433905726,0.323776572,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,12634,DB00126,10033371,452,9719,148,5797,1.0432139219505e-10,1.821557423,1.505193696,2.214617547,3.38947811353139e-09,DB0012610033371_,19.50258988,0.599691862,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,12636,DB00153,10033371,388,7035,84,3355,5.59681548671826e-12,2.202691019,1.729045977,2.833330031,2.23744935465231e-10,DB0015310033371_,22.22051439,0.789679803,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,12637,DB00227,10033371,112,2355,40,1763,3.81006266741721e-05,2.095774703,1.44020207,3.104143527,0.000350166,DB0022710033371_,7.957103018,0.739923272,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,lovastatin,DB00227
,12638,DB00455,10033371,363,9038,112,5006,2.93899924617067e-08,1.795108901,1.44415879,2.245532619,5.94929497001124e-07,DB0045510033371_,14.33482293,0.585065689,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,12639,DB01118,10033371,50,3013,51,4658,0.040336924,1.515525995,1.002347072,2.290714602,0.106301989,DB0111810033371_,2.241471278,0.41576257,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,12640,DB06605,10033371,360,13713,178,12855,1.56725422364745e-12,1.895876747,1.577180794,2.285600901,6.80913673860714e-11,DB0660510033371_,23.41017067,0.639681395,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,12642,DB00153,10033775,121,7302,30,3409,0.001439459,1.88289902,1.250837007,2.916231385,0.007431243,DB0015310033775_,4.902062199,0.632812621,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,12643,DB00227,10033775,36,2431,16,1787,0.119406308,1.653759364,0.891338609,3.202498993,0.240440862,DB0022710033775_,1.425281114,0.503051099,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,lovastatin,DB00227
,12644,DB00264,10033775,273,29334,123,24769,3.33893839507563e-09,1.87406088,1.508291076,2.339546744,8.33862192062357e-08,DB0026410033775_,16.29978278,0.62810767,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,12645,DB00455,10033775,108,9293,37,5081,0.014219868,1.595887347,1.087489823,2.389272036,0.047163311,DB0045510033775_,3.054139007,0.467429912,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,12646,DB00722,10033775,280,25123,166,25866,1.27026880580374e-08,1.73660075,1.42697061,2.118848078,2.79055708821991e-07,DB0072210033775_,15.0918544,0.55192961,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,12647,DB00761,10033775,144,15163,40,8585,3.84065930020406e-05,2.038194783,1.425470765,2.973449299,0.000352485,DB0076110033775_,7.950502235,0.712064506,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,12649,DB06605,10033775,77,13996,54,12979,0.1359247,1.322296444,0.920959329,1.910338671,0.263995327,DB0660510033775_,1.331823878,0.279369955,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,12681,DB00584,10021097,43,2038,51,1823,0.209482194,0.754247987,0.488150823,1.160595895,0.36058017,DB0058410021097_,1.020040963,-0.28203407,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,enalapril,DB00584
,12684,DB00695,10037400,396,27653,180,20348,5.03501023949111e-08,1.618813577,1.352609343,1.94346643,9.73484693968546e-07,DB0069510037400_,13.84238373,0.481693521,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,12688,DB00584,10053762,58,2023,53,1821,1,0.985069449,0.663129207,1.465884535,1,DB0058410053762_,0,-0.015043133,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,enalapril,DB00584
,12693,DB00175,10011906,228,7903,346,5760,1.60165698052218e-17,0.480293469,0.403148381,0.571386013,1.31151257735282e-15,DB0017510011906_,34.26759528,-0.733357967,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,12694,DB00433,10011906,467,7189,462,5558,0.000321418,0.781513168,0.682399314,0.895006969,0.002134801,DB0043310011906_,6.149381893,-0.246523279,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,12695,DB00758,10011906,291,8009,507,9567,4.05734396576977e-07,0.685634107,0.589711159,0.795990495,6.40909171515975e-06,DB0075810011906_,11.957793,-0.377411166,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,12696,DB00959,10011906,208,7870,204,4798,2.53372317998735e-06,0.621659259,0.508218718,0.760400584,3.25906111015256e-05,DB0095910011906_,10.33148631,-0.475363152,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,12697,DB01136,10011906,535,9349,768,10347,7.64718079901456e-06,0.770989035,0.686655974,0.865193525,8.57900756731104e-05,DB0113610011906_,9.363607226,-0.260081127,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,12698,DB01394,10011906,51,1389,80,1923,0.527970353,0.882643335,0.60440743,1.278958529,0.685443898,DB0139410011906_,0.377688624,-0.124834084,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,colchicine,DB01394
,12699,DB00695,10013709,822,27227,564,19964,0.235626573,1.068675415,0.957335507,1.193562868,0.392785672,DB0069510013709_,0.934491179,0.066419952,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,12701,DB00695,10069327,81,27968,50,20478,0.376182132,1.186136703,0.823250753,1.723749621,0.545949097,DB0069510069327_,0.605229537,0.170701558,NA,10069327,Product quality issue,10077536,Product issues,Prod,furosemide,DB00695
,12703,DB00982,10069327,55,3309,47,2054,0.123105004,0.726449124,0.481147269,1.100562582,0.245834847,DB0098210069327_,1.403095321,-0.319586827,NA,10069327,Product quality issue,10077536,Product issues,Prod,isotretinoin,DB00982
,12704,DB00028,10044390,37,13421,13,5602,0.644707313,1.187980517,0.616643997,2.437551758,0.780675898,DB0002810044390_,0.247595198,0.172254821,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,12706,DB00213,10044390,57,18838,36,13385,0.600165097,1.12503974,0.728006483,1.759137206,0.744646664,DB0021310044390_,0.29484545,0.117818359,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,12707,DB00230,10044390,43,19631,14,8637,0.388569458,1.351261731,0.724669692,2.67594645,0.558529418,DB0023010044390_,0.582447989,0.301038771,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,12712,DB00588,10044390,56,16468,29,8439,1,0.98955255,0.620681668,1.60858887,1,DB0058810044390_,0,-0.010502408,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,12713,DB00641,10044390,59,14065,47,12428,0.626716819,1.109187225,0.742716999,1.664742235,0.766233387,DB0064110044390_,0.266268473,0.103627517,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,12715,DB00695,10044390,106,27943,54,20474,0.030370663,1.438262504,1.026404664,2.035885375,0.085484058,DB0069510044390_,2.459425382,0.363435791,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,12717,DB00758,10044390,94,8206,75,9999,0.006518691,1.527130236,1.113755014,2.100218342,0.025299568,DB0075810044390_,3.676967956,0.423390311,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,12718,DB00761,10044390,61,15246,26,8599,0.263655926,1.323255254,0.822788217,2.183958201,0.425504759,DB0076110044390_,0.854479146,0.280094803,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,12720,DB00996,10044390,103,38850,44,22381,0.103352952,1.348562094,0.938388273,1.966531063,0.216062949,DB0099610044390_,1.532185481,0.299038909,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,12721,DB01068,10044390,38,13725,17,6823,0.775934181,1.111204003,0.611676048,2.101159374,0.877822795,DB0106810044390_,0.130310533,0.105444115,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,12723,DB11089,10044390,41,10134,18,8389,0.025496824,1.88547662,1.058360829,3.489239636,0.074605813,DB1108910044390_,2.595536854,0.634180638,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,docusate,DB11089
,12733,DB00929,10028813,51,1241,6,81,0.167112815,0.555109087,0.228649366,1.63015916,0.306970011,DB0092910028813_,1.181005219,-0.588590632,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,misoprostol,DB00929
,12741,DB01132,10013700,88,1197,45,1485,1.16715140215303e-06,2.425322304,1.660218757,3.584989965,1.64232198102744e-05,DB0113210013700_,11.01681438,0.885964424,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,pioglitazone,DB01132
,12742,DB00874,10013700,136,3199,22,1954,8.25228894908677e-11,3.7751982,2.38489534,6.24545312,2.7181881582299e-09,DB0087410013700_,19.7233003,1.328452885,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,guaifenesin,DB00874
,12745,DB00005,10015688,162,127920,56,42363,0.754544671,0.958018729,0.702781095,1.3228123,0.862125915,DB0000510015688_,0.148353945,-0.042887951,NA,10015688,Exostosis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,12746,DB00005,10033664,90,127992,21,42398,0.154701025,1.419636344,0.875176271,2.40462126,0.290378579,DB0000510033664_,1.236569763,0.350400743,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,12753,DB00186,10006093,80,16821,71,9937,0.014169725,0.665669781,0.47698524,0.930526757,0.047053404,DB0018610006093_,3.056472076,-0.406961556,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,lorazepam,DB00186
,12754,DB01136,10006093,107,9777,128,10987,0.646096397,0.939377304,0.718718367,1.225844107,0.781649463,DB0113610006093_,0.246348896,-0.062538066,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,carvedilol,DB01136
,12759,DB00186,10021097,316,16585,235,9773,0.008546017,0.792396435,0.665881074,0.943924176,0.031393647,DB0018610021097_,3.461149729,-0.232693464,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,lorazepam,DB00186
,12760,DB01136,10021097,372,9512,468,10647,0.104620651,0.889727215,0.772162892,1.024646593,0.217941205,DB0113610021097_,1.523529955,-0.116840363,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,carvedilol,DB01136
,12767,DB00959,10061818,62,8016,53,4949,0.083604899,0.722266893,0.49153329,1.064526536,0.184435985,DB0095910061818_,1.690452842,-0.325360551,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,12768,DB06626,10011906,52,636,146,1306,0.066279059,0.731470898,0.514966134,1.02599113,0.1546786,DB0662610011906_,1.866405866,-0.312697843,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,axitinib,DB06626
,12769,DB01261,10020751,42,3739,20,3283,0.028952672,1.843730447,1.056123692,3.322040273,0.082361579,DB0126110020751_,2.49663622,0.611790936,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,sitagliptin,DB01261
,12770,DB01261,10028810,45,3736,27,3276,0.124147025,1.461375464,0.885078608,2.45543159,0.247296772,DB0126110028810_,1.397166156,0.379378091,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,sitagliptin,DB01261
,12775,DB01164,10042674,56,6468,75,7861,0.597962802,0.907510288,0.629188376,1.302253403,0.742966308,DB0116410042674_,0.297104582,-0.097050376,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,12778,DB00390,10013573,225,3920,128,3173,0.001737917,1.422772687,1.134155562,1.790834398,0.008656649,DB0039010013573_,4.749427608,0.352607564,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,digoxin,DB00390
,12780,DB00390,10013710,56,4089,66,3235,0.034193811,0.671321882,0.460176381,0.976372605,0.09379924,DB0039010013710_,2.366598529,-0.398506552,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,12786,DB00390,10050845,31,4114,32,3269,0.310674901,0.769805301,0.453264751,1.305822312,0.47808016,DB0039010050845_,0.737976863,-0.261617652,NA,10050845,Cardioactive drug level increased,10022891,Investigations,Inv,digoxin,DB00390
,12788,DB00390,10070863,189,3956,146,3155,0.821952598,1.032409857,0.823111953,1.296991794,0.905187868,DB0039010070863_,0.099612768,0.031895737,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,digoxin,DB00390
,12790,DB00215,10022523,120,10983,79,5197,0.026656464,0.718758915,0.535533905,0.969259482,0.077233814,DB0021510022523_,2.56091791,-0.330229284,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,12792,DB00338,10022523,78,33596,35,22237,0.054943218,1.475067969,0.977655744,2.266143566,0.134230178,DB0033810022523_,2.008199203,0.38870407,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,12794,DB00215,10047700,347,10756,103,5173,1.2826950571492e-05,1.620213255,1.293302357,2.044149041,0.000135133,DB0021510047700_,8.909252382,0.482557779,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,12795,DB00776,10047700,72,1833,26,1313,0.002425062,1.983232955,1.242808373,3.255019043,0.011383653,DB0077610047700_,4.475576884,0.684728319,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,oxcarbazepine,DB00776
,12796,DB01065,10047700,182,4149,69,2982,4.40015476497694e-06,1.895608141,1.423168842,2.549102615,5.28415619764747e-05,DB0106510047700_,9.848212518,0.639539706,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,melatonin,DB01065
,12798,DB00338,10048294,154,33520,118,22154,0.238257328,0.862560904,0.673829333,1.106491134,0.395873271,DB0033810048294_,0.926661143,-0.147849519,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,12800,DB01065,10048294,35,4296,36,3015,0.115925076,0.682370747,0.415018971,1.120911509,0.235051538,DB0106510048294_,1.447950477,-0.382182151,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,melatonin,DB01065
,12804,DB08934,10002034,119,4370,147,6057,0.378556762,1.122019321,0.87077545,1.443294254,0.548577032,DB0893410002034_,0.600427567,0.115130027,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,sofosbuvir,DB08934
,12807,DB01164,10007882,22,6502,38,7898,0.196259676,0.703267207,0.395736052,1.221157432,0.34453253,DB0116410007882_,1.065566766,-0.352018365,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,calcium chloride,DB01164
,12808,DB01164,10024774,36,6488,58,7878,0.21202515,0.753682755,0.482328649,1.163583872,0.36381376,DB0116410024774_,1.011113192,-0.282783749,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,calcium chloride,DB01164
,12809,DB06404,10053762,64,3005,23,877,0.436769974,0.812137549,0.493947672,1.379168614,0.605318309,DB0640410053762_,0.502000829,-0.208085558,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,human c1-esterase inhibitor,DB06404
,12811,DB00051,10040047,115,25616,95,11325,1.15391789499099e-05,0.535163695,0.403905425,0.710559113,0.000122996,DB0005110040047_,9.003361418,-0.625182608,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,adalimumab,DB00051
,12812,DB00065,10040047,45,9419,31,4926,0.275503028,0.759211933,0.469279539,1.242702503,0.438791391,DB0006510040047_,0.823731171,-0.275474314,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,infliximab,DB00065
,12815,DB00112,10033371,284,5649,172,3919,0.172443038,1.145449557,0.940230434,1.398741356,0.314059606,DB0011210033371_,1.158172484,0.135797186,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,12816,DB00186,10033371,648,16253,212,9796,2.11055879893306e-15,1.842232868,1.571830146,2.166126738,1.36137516637928e-13,DB0018610033371_,29.62511087,0.610978351,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,12817,DB00273,10033371,330,8151,49,2144,0.000124952,1.771330631,1.303588177,2.452348787,0.000965134,DB0027310033371_,6.943243123,0.571731033,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,12818,DB00544,10033371,69,2366,59,2594,0.179147455,1.282121906,0.888290606,1.855566345,0.32281517,DB0054410033371_,1.130675349,0.248516445,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,fluorouracil,DB00544
,12819,DB00650,10033371,69,2062,42,1972,0.026427612,1.570975267,1.049566733,2.375930343,0.076701792,DB0065010033371_,2.567830206,0.451696616,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,leucovorin,DB00650
,12820,DB00762,10033371,47,1116,36,1333,0.056437326,1.559118792,0.980878091,2.496491614,0.136875357,DB0076210033371_,1.988684571,0.444120785,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,irinotecan,DB00762
,12847,DB01137,10013700,1321,6451,265,5328,2.77718936139611e-114,4.116344265,3.586322654,4.738902124,6.34768890124319e-111,DB0113710013700_,253.7388545,1.414965455,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,levofloxacin,DB01137
,12849,DB01137,10043248,50,7722,63,5530,0.002928762,0.568399758,0.383463007,0.838602736,0.013248391,DB0113710043248_,4.323879204,-0.564930309,NA,10043248,Tendon rupture,10022117,"Injury, poisoning and procedural complications",Inj&P,levofloxacin,DB01137
,12850,DB00635,10061822,238,32815,99,23695,2.27664982425114e-06,1.735883265,1.36669166,2.218737564,2.96907668719628e-05,DB0063510061822_,10.42467444,0.55151637,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,12851,DB01137,10061822,59,7713,27,5566,0.049043084,1.57686023,0.982759306,2.590325053,0.123181792,DB0113710061822_,2.094094028,0.455435674,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,12854,DB01190,10013700,1981,2953,455,1830,1.60461407060573e-67,2.697768735,2.396152029,3.041136814,1.72152166717843e-64,DB0119010013700_,146.8222374,0.992425037,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,clindamycin,DB01190
,12855,DB00480,10000081,374,67054,252,67410,7.83661346046635e-07,1.491994029,1.267857766,1.758100033,1.15527417166774e-05,DB0048010000081_,11.36858777,0.4001135,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,12856,DB00480,10056819,346,67082,239,67423,7.35086258474394e-06,1.455046579,1.229894663,1.723658705,8.28192983454755e-05,DB0048010056819_,9.398849452,0.375037913,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,12857,DB00480,10061822,968,66460,876,66786,0.025910962,1.110441904,1.011767228,1.218906739,0.075494058,DB0048010061822_,2.583701322,0.104758048,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,12858,DB00112,10015150,78,5855,32,4059,0.014365548,1.689718622,1.104009097,2.641149325,0.047583444,DB0011210015150_,3.045270397,0.524562019,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,bevacizumab,DB00112
,12859,DB00112,10037087,52,5881,39,4052,0.748094642,0.918673237,0.593674282,1.432091075,0.856916706,DB0011210037087_,0.154414558,-0.084824783,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,bevacizumab,DB00112
,12862,DB00531,10000880,115,7137,77,6439,0.049163078,1.347409283,0.998804702,1.826070233,0.123418319,DB0053110000880_,2.092175723,0.298183699,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyclophosphamide,DB00531
,12863,DB00541,10000880,52,3082,57,4240,0.242531865,1.255003435,0.842380735,1.866248536,0.400726032,DB0054110000880_,0.914477297,0.22713831,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,vincristine,DB00541
,12864,DB00563,10000880,28,46618,37,15311,4.17025776246645e-08,0.248562034,0.146452973,0.41745257,8.18329416098773e-07,DB0056310000880_,14.01600087,-1.392062829,male,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,methotrexate,DB00563
,12865,DB00773,10000880,52,2271,55,2772,0.492565583,1.153994707,0.771102421,1.725011144,0.655465705,DB0077310000880_,0.422409295,0.143229581,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,etoposide,DB00773
,12868,DB01225,10037437,31,5013,30,4610,0.897989952,0.950246584,0.555424989,1.627816304,0.956338178,DB0122510037437_,0.044643686,-0.051033766,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enoxaparin,DB01225
,12869,DB01225,10043607,142,4902,135,4505,0.807290871,0.966658346,0.755614045,1.237210259,0.895894857,DB0122510043607_,0.10993222,-0.03391016,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,enoxaparin,DB01225
,12871,DB00480,10025482,1108,66320,843,66819,9.33539798482395e-10,1.324235525,1.20890718,1.451044397,2.61043548969253e-08,DB0048010025482_,17.46116368,0.280835331,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,12872,DB00480,10038428,418,67010,472,67190,0.080315336,0.8879733,0.776222146,1.015529067,0.178936142,DB0048010038428_,1.720726287,-0.118813604,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,12875,DB01261,10033645,95,3686,99,3204,0.215658327,0.834137899,0.620184507,1.121392086,0.368233021,DB0126110033645_,0.999039332,-0.181356543,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,sitagliptin,DB01261
,12879,DB00829,10015150,44,8008,15,4439,0.132972132,1.625948525,0.886387985,3.149242413,0.259912437,DB0082910015150_,1.347410486,0.486091353,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,diazepam,DB00829
,12881,DB00829,10019303,54,7998,20,4434,0.143739938,1.49680374,0.880104073,2.643614873,0.275151936,DB0082910019303_,1.290431841,0.403331995,NA,10019303,Heart rate increased,10022891,Investigations,Inv,diazepam,DB00829
,12883,DB00190,10016256,196,3101,211,4463,0.004486135,1.336830122,1.088902908,1.640744331,0.018729044,DB0019010016256_,3.977679804,0.290301231,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,12884,DB00203,10016256,1197,12681,464,8474,2.9338220723148e-23,1.723850488,1.541817212,1.929832851,4.02691974782216e-21,DB0020310016256_,46.9612852,0.544560445,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,12885,DB00448,10016256,273,4872,172,2952,0.725011794,0.961742303,0.787277953,1.177304747,0.838736631,DB0044810016256_,0.17585853,-0.039008741,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,12887,DB00737,10003239,110,2691,15,917,0.000459391,2.498308765,1.441383667,4.639378339,0.002877422,DB0073710003239_,5.850860598,0.915614009,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,meclizine,DB00737
,12888,DB00904,10003239,488,22581,167,14289,1.35705476622553e-12,1.849074786,1.545973663,2.220540399,5.98995542069487e-11,DB0090410003239_,23.53835205,0.614685398,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,12889,DB01156,10003239,275,13347,69,6259,1.44014706912928e-06,1.868929021,1.428047359,2.474487742,1.98710056231303e-05,DB0115610003239_,10.82624889,0.625365551,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,12890,DB00904,10016256,2011,21058,1034,13422,5.86071764524915e-08,1.239621277,1.145903681,1.341579551,1.11427821559041e-06,DB0090410016256_,13.7073037,0.214805911,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,12891,DB01156,10016256,748,12874,258,6070,1.85125581481827e-05,1.36694811,1.180950942,1.586079033,0.000186688,DB0115610016256_,8.586071128,0.312580598,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,12892,DB00737,10030124,43,2758,13,919,0.876748428,1.102135374,0.57859887,2.24438236,0.947373433,DB0073710030124_,0.054061931,0.097249547,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,meclizine,DB00737
,12893,DB00904,10030124,301,22768,163,14293,0.136829865,1.159283331,0.953755926,1.413100776,0.265282907,DB0090410030124_,1.326958449,0.147801996,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,12894,DB01156,10030124,52,13570,23,6305,0.901589152,1.050460034,0.630956884,1.800144559,0.95705878,DB0115610030124_,0.043890468,0.049228195,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,12896,DB00363,10018687,357,4271,596,6292,0.078496036,0.882466506,0.767342059,1.013781013,0.175844233,DB0036310018687_,1.738156717,-0.125034445,NA,10018687,Granulocytopenia,10005329,Blood and lymphatic system disorders,Blood,clozapine,DB00363
,12900,DB01104,10035664,416,15047,196,7090,1,1.000061039,0.839811571,1.194190953,1,DB0110410035664_,0,6.10370189713741e-05,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sertraline,DB01104
,12908,DB00451,10008469,342,46929,53,15366,5.52064963079654e-08,2.112969848,1.577316948,2.879659199,1.05881266359348e-06,DB0045110008469_,13.75836241,0.748094469,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,12909,DB00451,10008479,688,46583,190,15229,0.040199806,1.183794068,1.005588108,1.39900071,0.106073519,DB0045110008479_,2.243622849,0.168724592,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,12910,DB00451,10012174,618,46653,282,15137,4.04286702978735e-06,0.71105353,0.615872034,0.822533752,4.90499699413618e-05,DB0045110012174_,9.922670985,-0.341007563,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,12911,DB00451,10019194,74,47197,7,15412,0.000404035,3.452114252,1.593998962,8.885508634,0.002584583,DB0045110019194_,5.958191159,1.23898687,female,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,12912,DB00451,10020937,601,46670,109,15310,2.08953662495345e-09,1.808669823,1.471375061,2.241025802,5.43796734523776e-08,DB0045110020937_,16.7272754,0.592591671,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,12913,DB00451,10070863,309,46962,125,15294,0.044013072,0.805044688,0.651400988,0.99987793,0.113622553,DB0045110070863_,2.174873267,-0.21685749,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,12916,DB01202,10003239,72,6642,32,5686,0.002048518,1.926021418,1.251383814,3.024120843,0.009915347,DB0120210003239_,4.613671558,0.655456434,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,levetiracetam,DB01202
,12921,DB00005,10020568,75,128007,25,42394,1,0.993554993,0.624367483,1.631277862,1,DB0000510020568_,0,-0.006465866,NA,10020568,Hyperaesthesia,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,12922,DB00005,10040882,151,127931,75,42344,0.005417229,0.666397101,0.501859388,0.891355588,0.021800789,DB0000510040882_,3.825809114,-0.405869538,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,12923,DB00099,10003988,74,2311,45,1910,0.112927495,1.35900723,0.920799619,2.025040261,0.230493804,DB0009910003988_,1.467531299,0.306754455,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,filgrastim,DB00099
,12924,DB00441,10003988,56,2218,45,1849,0.919525949,1.037408502,0.684572621,1.579747702,0.964382416,DB0044110003988_,0.036267366,0.036725778,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,gemcitabine,DB00441
,12925,DB00515,10003988,29,1841,39,2112,0.542144564,0.85308208,0.506571756,1.421832152,0.6973995,DB0051510003988_,0.360396862,-0.158899511,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cisplatin,DB00515
,12926,DB00441,10008479,39,2235,24,1870,0.253461277,1.359519074,0.793973631,2.372666076,0.413983078,DB0044110008479_,0.881930181,0.307131015,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,gemcitabine,DB00441
,12927,DB00515,10008479,24,1846,30,2121,0.785239287,0.919166444,0.512275994,1.632896436,0.88348663,DB0051510008479_,0.12387912,-0.084288058,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,cisplatin,DB00515
,12935,DB00526,10037844,40,1558,33,1861,0.123862724,1.447685324,0.88544959,2.381559533,0.24688097,DB0052610037844_,1.398848963,0.369965953,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,oxaliplatin,DB00526
,12936,DB00544,10037844,51,2384,53,2600,0.843091135,1.049460719,0.697257747,1.578198102,0.920369237,DB0054410037844_,0.082980345,0.048276432,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,fluorouracil,DB00544
,12937,DB00650,10037844,57,2074,34,1980,0.033696481,1.600301737,1.023621438,2.535970823,0.092759283,DB0065010037844_,2.377747497,0.470192197,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,leucovorin,DB00650
,12939,DB00526,10061818,71,1527,92,1802,0.574134231,0.91077292,0.65350058,1.264973762,0.723950889,DB0052610061818_,0.323031722,-0.093461677,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,oxaliplatin,DB00526
,12940,DB00544,10061818,116,2319,105,2548,0.168706237,1.213807103,0.918266363,1.605934427,0.309097726,DB0054410061818_,1.174097787,0.193761787,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,fluorouracil,DB00544
,12941,DB00650,10061818,81,2050,81,1933,0.748648978,0.942913361,0.679850554,1.307866626,0.857346189,DB0065010061818_,0.153913488,-0.058780876,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,leucovorin,DB00650
,12943,DB00047,10017955,68,9217,105,8413,0.00073254,0.591150001,0.428539345,0.81092157,0.004247229,DB0004710017955_,5.461488552,-0.525685485,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,12944,DB00222,10017955,28,3178,48,3080,0.020390838,0.565399124,0.340624357,0.922285512,0.062749304,DB0022210017955_,2.7686078,-0.570223383,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,glimepiride,DB00222
,12945,DB00331,10017955,136,24810,217,20535,1.38341641677337e-09,0.518751104,0.41517716,0.646287232,3.73529537903318e-08,DB0033110017955_,17.10285384,-0.65633108,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,12946,DB00586,10017955,42,7067,25,2780,0.10359154,0.660904484,0.392699047,1.133875171,0.216404024,DB0058610017955_,1.530608137,-0.414145952,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,diclofenac,DB00586
,12947,DB00678,10017955,112,15487,136,10588,8.852031022666e-06,0.563050887,0.433930987,0.729328585,9.7619314214716e-05,DB0067810017955_,9.234435193,-0.574385269,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,12948,DB01136,10017955,156,9728,256,10859,0.000148327,0.680236864,0.552751658,0.834936607,0.001115691,DB0113610017955_,6.798281173,-0.385314212,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,12956,DB01156,10027951,39,13583,18,6310,1,1.006528803,0.561748383,1.87086308,1,DB0115610027951_,0,0.006507583,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,12957,DB00231,10047899,66,3230,24,2115,0.012350926,1.800512522,1.109161598,3.014931683,0.042117811,DB0023110047899_,3.167284569,0.588071359,NA,10047899,Weight increased,10022891,Investigations,Inv,temazepam,DB00231
,12958,DB00246,10047899,32,1042,34,667,0.053475912,0.60266037,0.356257182,1.017238706,0.131513319,DB0024610047899_,2.028647144,-0.506401475,NA,10047899,Weight increased,10022891,Investigations,Inv,ziprasidone,DB00246
,12959,DB00776,10047899,37,1868,25,1314,0.897338699,1.041062622,0.606815582,1.813563967,0.956338178,DB0077610047899_,0.044643686,0.040241943,NA,10047899,Weight increased,10022891,Investigations,Inv,oxcarbazepine,DB00776
,12964,DB00334,10039897,63,2786,96,2716,0.006226631,0.639815698,0.455964871,0.892525183,0.024380603,DB0033410039897_,3.713967422,-0.446575116,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,olanzapine,DB00334
,12966,DB00656,10039897,52,11961,27,6592,0.906311396,1.061426146,0.653864999,1.759524715,0.958165713,DB0065610039897_,0.042734537,0.059613425,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,12995,DB09072,10041347,106,6365,31,2504,0.179711647,1.345099866,0.891397843,2.083184598,0.323498194,DB0907210041347_,1.128561747,0.29646826,NA,10041347,Somnambulism,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,12997,DB06228,10012174,127,15785,84,15992,0.002344437,1.531702168,1.152556369,2.044547009,0.011070428,DB0622810012174_,4.503477839,0.426379645,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,rivaroxaban,DB06228
,12999,DB06228,10017826,35,15877,68,16008,0.00148548,0.518965947,0.334753379,0.79188137,0.007629866,DB0622810017826_,4.875684987,-0.65591701,NA,10017826,Gastric ulcer haemorrhage,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,13000,DB00338,10017944,170,33504,77,22195,0.006104931,1.462559723,1.110338962,1.941328756,0.024002411,DB0033810017944_,3.729601001,0.380188135,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,13001,DB06228,10017944,42,15870,35,16041,0.425740029,1.212920774,0.755572645,1.957898676,0.594478244,DB0622810017944_,0.520071159,0.193031314,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,13002,DB00338,10062237,145,33529,141,22131,0.001289654,0.678802595,0.534241429,0.862586867,0.006782422,DB0033810062237_,4.993421008,-0.387424923,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,13003,DB06228,10062237,32,15880,47,16029,0.114589195,0.687250577,0.424148403,1.100646441,0.233014538,DB0622810062237_,1.45665443,-0.375056312,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,rivaroxaban,DB06228
,13016,DB00169,10013916,70,38621,37,18138,0.603970702,0.88851732,0.588100545,1.362095175,0.747438637,DB0016910013916_,0.291103068,-0.118201138,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,13017,DB00451,10013916,88,47183,17,15402,0.05300171,1.689685939,0.997318285,3.031644598,0.130634342,DB0045110013916_,2.035353143,0.524542677,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,13018,DB00476,10013916,68,17189,18,6159,0.272332084,1.353576447,0.795013494,2.420868145,0.43528983,DB0047610013916_,0.831743195,0.302750309,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,13020,DB00996,10013916,110,38843,49,22376,0.138487113,1.29320668,0.915157109,1.850546523,0.267666735,DB0099610013916_,1.318012598,0.257124933,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,13024,DB00169,10014625,57,38634,53,18122,0.000446268,0.504459098,0.340781642,0.74795442,0.002809619,DB0016910014625_,5.874706351,-0.684268517,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,13025,DB00451,10014625,108,47163,60,15359,0.001197059,0.58619036,0.423411442,0.818122343,0.006396564,DB0045110014625_,5.05199427,-0.534110696,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,13027,DB00996,10014625,115,38838,89,22336,0.041162215,0.743139735,0.55831366,0.991844092,0.108022047,DB0099610014625_,2.225419935,-0.296871183,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,13031,DB00169,10015916,98,38593,24,18151,0.003367541,1.920447303,1.218434326,3.140291312,0.01484293,DB0016910015916_,4.21023161,0.652558129,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,13034,DB00996,10015916,66,38887,30,22395,0.339708585,1.266999455,0.810905998,2.021772578,0.508803108,DB0099610015916_,0.675694158,0.236651471,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,gabapentin,DB00996
,13038,DB00213,10013968,1018,17877,562,12859,7.33679988209712e-07,1.302927244,1.1712713,1.450500764,1.08867805210577e-05,DB0021310013968_,11.4279613,0.264613459,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,13039,DB00424,10013968,47,1147,10,418,0.16721558,1.712345712,0.844119582,3.836315574,0.307135427,DB0042410013968_,1.180466498,0.537864192,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hyoscyamine,DB00424
,13042,DB01362,10066973,34,832,25,565,0.787604077,0.923609171,0.528562349,1.633908995,0.884935161,DB0136210066973_,0.122240901,-0.079466272,NA,10066973,Contrast media allergy,10021428,Immune system disorders,Immun,iohexol,DB01362
,13043,DB00480,10020583,62,67366,79,67583,0.177495244,0.787341413,0.555188205,1.112222627,0.320650342,DB0048010020583_,1.137404025,-0.239093309,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,13044,DB00480,10048294,67,67361,102,67560,0.008690505,0.658808797,0.476564687,0.905597847,0.031830269,DB0048010048294_,3.447337592,-0.417321928,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,13047,DB00722,10024690,39,25364,30,26002,0.278225264,1.33268756,0.806578323,2.222179632,0.44201578,DB0072210024690_,0.816409697,0.287197625,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,lisinopril,DB00722
,13050,DB00811,10010774,35,2763,43,4113,0.417658039,1.211608146,0.750669966,1.943675112,0.586736942,DB0081110010774_,0.533178699,0.191948523,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ribavirin,DB00811
,13051,DB08934,10010774,73,4416,61,6143,0.003579745,1.664612653,1.165816781,2.383901575,0.015599588,DB0893410010774_,4.160510803,0.509592455,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sofosbuvir,DB08934
,13052,DB00811,10012378,121,2677,131,4025,0.012756891,1.388678495,1.070156924,1.800808633,0.043232966,DB0081110012378_,3.14115197,0.328352572,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ribavirin,DB00811
,13053,DB08934,10012378,89,4400,114,6090,0.615459798,1.080553708,0.807271603,1.442571812,0.756846991,DB0893410012378_,0.278594172,0.077473602,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,sofosbuvir,DB08934
,13054,DB00811,10016256,433,2365,588,3568,0.128536787,1.110956034,0.968542875,1.273643588,0.253562193,DB0081110016256_,1.37214615,0.105220937,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,13055,DB00811,10028813,336,2462,297,3859,8.27519489676173e-12,1.773032769,1.499757952,2.096907331,3.20343884921034e-10,DB0081110028813_,21.86162606,0.572691509,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ribavirin,DB00811
,13056,DB08934,10028813,573,3916,478,5726,8.1578857481612e-18,1.75266464,1.539072053,1.996750482,6.85079958116349e-16,DB0893410028813_,34.91699612,0.561137281,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sofosbuvir,DB08934
,13058,DB08934,10047899,34,4455,34,6170,0.217405173,1.384897308,0.833807664,2.300157778,0.370361643,DB0893410047899_,0.993275337,0.325625991,NA,10047899,Weight increased,10022891,Investigations,Inv,sofosbuvir,DB08934
,13063,DB00005,10011732,142,127940,37,42382,0.225540372,1.271328652,0.879904762,1.878790381,0.380313617,DB0000510011732_,0.966759058,0.240062536,NA,10011732,Cyst,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,13065,DB00563,10012378,444,46202,108,15240,0.00404153,1.356048481,1.09564231,1.690753398,0.01722861,DB0056310012378_,4.061183922,0.304574942,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,13066,DB00563,10024690,285,46361,87,15261,0.587662598,1.078338549,0.844742962,1.388193175,0.734656832,DB0056310024690_,0.308351784,0.075421476,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,methotrexate,DB00563
,13072,DB01068,10000059,137,13626,60,6780,0.447454817,1.136121923,0.831646195,1.568022769,0.615213916,DB0106810000059_,0.48578524,0.127620642,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,13073,DB01068,10002855,537,13226,217,6623,0.008303382,1.239143004,1.053415577,1.461600235,0.030677405,DB0106810002855_,3.484228902,0.214420015,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,13074,DB01068,10025482,442,13321,131,6709,4.62880972498094e-08,1.699267055,1.391962804,2.085936325,8.99913192463935e-07,DB0106810025482_,13.92096753,0.530197014,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,13075,DB00005,10066083,68,128014,29,42390,0.242499204,0.776457354,0.495805239,1.244300877,0.400697255,DB0000510066083_,0.914549113,-0.253013559,NA,10066083,Injection site injury,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,13080,DB00028,10040047,76,13382,56,5559,0.001484626,0.563807681,0.393386403,0.812235965,0.007626225,DB0002810040047_,4.876162265,-0.573042076,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,13081,DB00531,10040047,211,7041,262,6254,0.000363737,0.715349976,0.59192336,0.863669603,0.00236859,DB0053110040047_,6.045460395,-0.334983379,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,13088,DB00028,10051055,46,13412,40,5575,0.000817171,0.478031009,0.30567962,0.750376414,0.004659293,DB0002810051055_,5.368891477,-0.738079676,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,human immunoglobulin g,DB00028
,13089,DB00531,10051055,72,7180,72,6444,0.557273723,0.897500661,0.637122467,1.26425529,0.71044122,DB0053110051055_,0.341869065,-0.108141422,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,cyclophosphamide,DB00531
,13093,DB00331,10000891,60,24886,101,20651,1.10481351526139e-05,0.492978229,0.351830067,0.685607157,0.000118283,DB0033110000891_,9.042434088,-0.707290267,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,metformin,DB00331
,13096,DB08908,10028596,58,10615,33,3246,0.006013231,0.537501328,0.344026621,0.852449518,0.023707483,DB0890810028596_,3.74196454,-0.620824049,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,dimethyl fumarate,DB08908
,13097,DB00126,10015090,76,10095,49,5896,0.578355081,0.905883385,0.623403731,1.327055946,0.727110525,DB0012610015090_,0.318676785,-0.098844695,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,13098,DB00338,10015090,194,33480,117,22155,0.450466122,1.097258114,0.867246958,1.393246812,0.618173855,DB0033810015090_,0.480985542,0.092814445,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,13101,DB00722,10015090,129,25274,129,25903,0.85170315,1.024891621,0.796140068,1.319338157,0.927167107,DB0072210015090_,0.075621463,0.024586871,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,13106,DB00316,10018867,104,65370,141,36812,8.53952390613551e-12,0.415360923,0.319126504,0.539123424,3.2960555928454e-10,DB0031610018867_,21.83312445,-0.878607444,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,13109,DB00480,10018867,34,67394,54,67608,0.042170897,0.631634664,0.398676163,0.988132165,0.110023888,DB0048010018867_,2.207057775,-0.459444115,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,13110,DB00706,10018867,7,1068,104,15821,1,0.997074139,0.390203096,2.135705429,1,DB0070610018867_,0,-0.00293015,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,tamsulosin,DB00706
,13111,DB00722,10018867,42,25361,104,25928,4.76325357000241e-07,0.412853688,0.281285261,0.596442701,7.43039288353195e-06,DB0072210018867_,11.80993182,-0.884662014,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,13116,DB00316,10018964,104,65370,92,36861,0.002182604,0.63740566,0.476707485,0.853513532,0.010453447,DB0031610018964_,4.560823488,-0.450348998,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,13117,DB00338,10018964,76,33598,90,22182,0.000178762,0.557540724,0.405155805,0.765517221,0.001311405,DB0033810018964_,6.636656133,-0.58421973,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,13120,DB00480,10018964,57,67371,42,67620,0.13245491,1.36215054,0.898314284,2.080412417,0.25918893,DB0048010018964_,1.350198023,0.30906473,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,13121,DB00682,10018964,149,19310,187,16177,0.00027073,0.667529028,0.534040218,0.833193801,0.001855338,DB0068210018964_,6.289688506,-0.404172401,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,13123,DB00722,10018964,51,25352,55,25977,0.845990374,0.950117534,0.63589678,1.417368624,0.92255718,DB0072210018964_,0.080605921,-0.051169582,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,13128,DB00316,10028533,32,65442,44,36909,0.000112336,0.410179403,0.251731054,0.661777589,0.000881546,DB0031610028533_,7.033832884,-0.891160646,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,13129,DB00338,10028533,26,33648,41,22231,0.000626211,0.418979747,0.245985342,0.701727736,0.003734111,DB0033810028533_,5.590245499,-0.869932698,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,omeprazole,DB00338
,13132,DB00480,10028533,175,67253,269,67393,9.27337023560162e-06,0.65191752,0.535632982,0.79178858,0.000101669,DB0048010028533_,9.193791774,-0.427837228,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,13139,DB00126,10033661,33,10138,40,5905,0.002159291,0.480545032,0.293323871,0.782473714,0.010362033,DB0012610033661_,4.569606872,-0.732834336,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,ascorbic acid,DB00126
,13140,DB00316,10033661,224,65250,220,36733,7.39368421110827e-09,0.573226919,0.473520961,0.693890824,1.70926112127512e-07,DB0031610033661_,15.58203447,-0.556473621,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,13141,DB00338,10033661,129,33545,153,22119,9.35898930373691e-07,0.555973761,0.436109725,0.707801228,1.3520254677039e-05,DB0033810033661_,11.21132165,-0.587034178,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,omeprazole,DB00338
,13143,DB00682,10033661,48,19411,65,16299,0.013620634,0.620086305,0.417643694,0.914975335,0.045537822,DB0068210033661_,3.08921205,-0.477896608,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,warfarin,DB00682
,13145,DB00722,10033661,75,25328,98,25934,0.127471275,0.783622375,0.571964856,1.069995316,0.252035676,DB0072210033661_,1.378184628,-0.243828039,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,lisinopril,DB00722
,13149,DB00126,10038063,34,10137,23,5922,0.584899982,0.8636079,0.493542174,1.537015938,0.732568728,DB0012610038063_,0.311198116,-0.146636433,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,13150,DB00316,10038063,153,65321,107,36846,0.092758655,0.806590179,0.625730543,1.042823702,0.199636554,DB0031610038063_,1.611256794,-0.214939572,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,13151,DB00338,10038063,98,33576,71,22201,0.582005252,0.912667397,0.665273642,1.257402111,0.73018552,DB0033810038063_,0.31445664,-0.091383762,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,13154,DB00480,10038063,95,67333,76,67586,0.146343951,1.254691943,0.918025378,1.719769265,0.278829661,DB0048010038063_,1.277154216,0.226890079,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,13155,DB00682,10038063,129,19330,156,16208,0.00228728,0.693380248,0.544274262,0.882050856,0.010855195,DB0068210038063_,4.523111547,-0.366176732,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,13157,DB00722,10038063,71,25332,116,25916,0.002012764,0.626188473,0.459100533,0.849006156,0.009779208,DB0072210038063_,4.627496821,-0.468103879,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,13166,DB00215,10060933,46,11057,10,5266,0.021436859,2.190703883,1.089386084,4.872988904,0.065306888,DB0021510060933_,2.72865776,0.7842229,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,13167,DB00381,10060933,109,29251,68,22819,0.150274722,1.250464439,0.914825091,1.719561679,0.284354694,DB0038110060933_,1.257532896,0.223515033,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,13169,DB00682,10060933,121,19338,56,16308,0.000147227,1.822125674,1.315920002,2.549940327,0.001108528,DB0068210060933_,6.804722123,0.600003772,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,13170,DB00695,10060933,112,27937,75,20453,0.603774473,1.093307736,0.808359823,1.485702151,0.747337482,DB0069510060933_,0.291238412,0.089207721,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,13171,DB00722,10060933,90,25313,69,25963,0.080220676,1.3378289,0.966336223,1.859009422,0.178777332,DB0072210060933_,1.721614201,0.291048076,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,13172,DB00761,10060933,60,15247,27,8598,0.371532299,1.253167374,0.782638689,2.054915004,0.541187391,DB0076110060933_,0.613989681,0.225674246,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,13174,DB01136,10060933,26,9858,35,11080,0.522406368,0.834949689,0.482280454,1.428442015,0.680971578,DB0113610060933_,0.384234709,-0.180383809,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,13176,DB01261,10060933,56,3725,35,3268,0.138370547,1.403635267,0.901451492,2.212638813,0.267474576,DB0126110060933_,1.318730759,0.33906549,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,13178,DB14726,10008190,62,1955,97,2751,0.566967785,0.899415993,0.639633541,1.256870309,0.718212957,DB1472610008190_,0.330989157,-0.106009623,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,dabigatran,DB14726
,13179,DB00005,10005554,76,128006,19,42400,0.341749537,1.324921227,0.793113934,2.320611823,0.510986419,DB0000510005554_,0.671412266,0.281353007,NA,10005554,Blood glucose abnormal,10022891,Investigations,Inv,etanercept,DB00005
,13183,DB00451,10064658,45,47226,23,15396,0.08995002,0.637844921,0.377742567,1.104905752,0.195125548,DB0045110064658_,1.634112089,-0.449660096,NA,10064658,Osteonecrosis of jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,13191,DB00722,10002424,464,24939,2169,23863,8.56736693617849e-266,0.204721139,0.184509858,0.226765047,1.12596619958726e-261,DB0072210002424_,600.8560678,-1.586106521,male,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,13192,DB00196,10013700,316,4767,38,3247,2.89644835159279e-34,5.663346639,4.023141291,8.175741748,8.4125022012836e-32,DB0019610013700_,71.55300402,1.734014997,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,fluconazole,DB00196
,13193,DB00514,10013700,53,2113,10,1526,1.44910540716085e-05,3.82647813,1.918736845,8.463904972,0.000150493,DB0051410013700_,8.801595107,1.341944832,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,dextromethorphan,DB00514
,13194,DB00480,10019909,64,67364,183,67479,1.78059463851952e-14,0.35030632,0.259245462,0.468189464,1.00977195412051e-12,DB0048010019909_,27.6212966,-1.048947307,male,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,13196,DB01164,10010774,62,6462,72,7864,0.794239605,1.047960785,0.732712515,1.494983294,0.888516684,DB0116410010774_,0.118201854,0.046846167,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,calcium chloride,DB01164
,13197,DB01164,10020772,115,6409,131,7805,0.605888095,1.069054246,0.82300402,1.387087932,0.748919284,DB0116410020772_,0.289124067,0.066774376,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,calcium chloride,DB01164
,13198,DB00512,10062237,43,4694,82,5016,0.002094881,0.56039708,0.377285167,0.822113778,0.010107188,DB0051210062237_,4.594508449,-0.579109676,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,vancomycin,DB00512
,13200,DB00211,10011906,106,1330,171,1460,0.002966992,0.680560554,0.522895013,0.882657404,0.0133815,DB0021110011906_,4.313882102,-0.384838476,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,midodrine,DB00211
,13201,DB01015,10011906,274,9613,383,8998,5.31831182993698e-07,0.669655102,0.569819797,0.786221585,8.19893410263305e-06,DB0101510011906_,11.7115064,-0.400992472,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,13209,DB00254,10006451,93,5842,34,3354,0.025544177,1.570311381,1.047080774,2.405183191,0.074708646,DB0025410006451_,2.594159456,0.451273932,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,doxycycline,DB00254
,13210,DB00341,10006451,186,11219,34,5034,1.97637039140477e-07,2.454560127,1.693023974,3.656114297,3.35804109489815e-06,DB0034110006451_,12.60415276,0.897947571,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,cetirizine,DB00341
,13211,DB00480,10006451,609,66819,400,67262,2.75159630031332e-11,1.532580235,1.348097889,1.743742159,9.82019127681408e-10,DB0048010006451_,20.74141033,0.426952743,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,13212,DB00761,10006451,221,15086,59,8566,5.73321779861743e-08,2.126823937,1.587148226,2.888577593,1.09258634629831e-06,DB0076110006451_,13.72696288,0.754629758,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,13213,DB00787,10006451,204,16796,131,17117,3.59675750745229e-05,1.586982106,1.266709188,1.993983918,0.00033289,DB0078710006451_,8.007698336,0.461834166,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,acyclovir,DB00787
,13214,DB00820,10006451,208,11707,46,5770,1.7133836239705e-07,2.228531592,1.609927062,3.142786477,2.95804850942953e-06,DB0082010006451_,12.73098079,0.801342889,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,tadalafil,DB00820
,13215,DB00254,10008479,60,5875,28,3360,0.435957532,1.225549322,0.768567416,1.997827893,0.604544644,DB0025410008479_,0.503279758,0.20338917,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,13216,DB00341,10008479,185,11220,66,5002,0.129621992,1.249578224,0.936632366,1.684691912,0.255128538,DB0034110008479_,1.365987791,0.222806073,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,13217,DB00480,10008479,443,66985,413,67249,0.287881983,1.076834307,0.939226145,1.234917782,0.452854839,DB0048010008479_,0.792183649,0.074025539,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,13218,DB00761,10008479,341,14966,122,8503,8.18181403642155e-06,1.588009036,1.285360185,1.972639938,9.12426737154605e-05,DB0076110008479_,9.301987857,0.462481053,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,13219,DB00787,10008479,124,16876,131,17117,0.753710801,0.960072602,0.744174358,1.238055394,0.861510193,DB0078710008479_,0.149068391,-0.04074637,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,13220,DB00820,10008479,687,11228,163,5653,1.86888535998746e-19,2.121920921,1.78065293,2.540423018,1.83983714184533e-17,DB0082010008479_,38.53426952,0.752321773,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,13221,DB00254,10013968,228,5707,137,3251,0.657020966,0.948038695,0.760178019,1.185814842,0.790325428,DB0025410013968_,0.235310484,-0.05335996,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxycycline,DB00254
,13222,DB00480,10013968,1318,66110,1371,66291,0.34982887,0.963964876,0.89243001,1.041246105,0.519417718,DB0048010013968_,0.655046868,-0.036700421,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,13223,DB00761,10013968,1213,14094,553,8072,1.50186664972406e-05,1.25623779,1.130798301,1.396843077,0.000155236,DB0076110013968_,8.77056275,0.228121374,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,13230,DB00254,10033371,215,5720,63,3325,9.16337043995909e-07,1.983645965,1.486298663,2.67926258,1.32704788988609e-05,DB0025410033371_,11.22996862,0.684936548,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,13231,DB00341,10033371,470,10935,118,4950,3.65629809465916e-09,1.802969464,1.466108172,2.231670564,9.03674616061269e-08,DB0034110033371_,16.21938157,0.589435008,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,13232,DB00787,10033371,362,16638,266,16982,5.46541951854474e-05,1.389019834,1.180634269,1.635848057,0.000476558,DB0078710033371_,7.648920126,0.328598343,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,13233,DB00820,10033371,714,11201,191,5625,2.15129814064817e-15,1.877225513,1.592624661,2.221080146,1.38425634337667e-13,DB0082010033371_,29.60844315,0.629794896,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,13241,DB00341,10036790,82,11323,28,5040,0.254584716,1.303480539,0.838366381,2.082571929,0.415276112,DB0034110036790_,0.878811649,0.265038025,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,13242,DB00480,10036790,108,67320,99,67563,0.531806206,1.094829267,0.825565039,1.453310531,0.68868216,DB0048010036790_,0.372975421,0.090598431,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,13243,DB00761,10036790,96,15211,34,8591,0.021629455,1.594667875,1.067163363,2.435004061,0.065790551,DB0076110036790_,2.721279047,0.466665485,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,13244,DB00787,10036790,34,16966,35,17213,1,0.985570043,0.59604813,1.627972253,1,DB0078710036790_,0,-0.014535081,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,13245,DB00820,10036790,147,11768,47,5769,0.010978783,1.533231231,1.095303671,2.180744928,0.038359338,DB0082010036790_,3.260757284,0.427377424,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,13248,DB00480,10037368,30,67398,25,67637,0.503610726,1.204251919,0.68455042,2.135839415,0.66474542,DB0048010037368_,0.408351139,0.18585856,NA,10037368,Pulmonary congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,13252,DB00254,10037660,119,5816,92,3296,0.029722877,0.733078241,0.551784469,0.97645579,0.084097505,DB0025410037660_,2.475778384,-0.310502841,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,13253,DB00480,10037660,1029,66399,1138,66524,0.022968707,0.905927028,0.831297897,0.987174648,0.068832796,DB0048010037660_,2.676074964,-0.09879652,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,13254,DB00787,10037660,474,16526,573,16675,0.004270042,0.834689065,0.736030445,0.946200481,0.018012863,DB0078710037660_,4.01666915,-0.180696001,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,13265,DB00813,10069327,188,10384,103,10065,2.73246333393637e-06,1.769113191,1.38160454,2.275650363,3.48993191120104e-05,DB0081310069327_,10.26304324,0.570478399,NA,10069327,Product quality issue,10077536,Product issues,Prod,fentanyl,DB00813
,13272,DB00281,10023683,40,11418,21,5650,0.891676741,0.942542608,0.54208783,1.684284392,0.955005127,DB0028110023683_,0.04603857,-0.059174153,NA,10023683,Lagophthalmos,10015919,Eye disorders,Eye,lidocaine,DB00281
,13280,DB00316,10007739,218,65256,89,36864,0.010368752,1.383716546,1.076171147,1.791730701,0.036641927,DB0031610007739_,3.306562143,0.324773028,NA,10007739,Cataract,10015919,Eye disorders,Eye,acetaminophen,DB00316
,13281,DB00476,10007739,53,17204,18,6159,1,1.054086462,0.607012337,1.913739466,1,DB0047610007739_,0,0.052674479,NA,10007739,Cataract,10015919,Eye disorders,Eye,duloxetine,DB00476
,13282,DB00996,10007739,168,38785,67,22358,0.009902858,1.445443358,1.082192696,1.949598129,0.035278173,DB0099610007739_,3.34449083,0.368416097,NA,10007739,Cataract,10015919,Eye disorders,Eye,gabapentin,DB00996
,13283,DB14513,10007739,45,7132,24,3540,0.798019465,0.930672258,0.554049704,1.599833976,0.890838937,DB1451310007739_,0.115591635,-0.071848096,NA,10007739,Cataract,10015919,Eye disorders,Eye,magnesium,DB14513
,13289,DB00316,10028521,54,65420,24,36929,0.348110994,1.270130981,0.771688843,2.148744631,0.517641924,DB0031610028521_,0.658471543,0.23912003,NA,10028521,Mydriasis,10015919,Eye disorders,Eye,acetaminophen,DB00316
,13294,DB01222,10008469,130,9144,47,5358,0.004627319,1.620684438,1.150462507,2.317446703,0.019213187,DB0122210008469_,3.952158435,0.482848552,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,13295,DB01222,10028810,177,9097,76,5329,0.025270502,1.364263797,1.034641338,1.813299356,0.074100921,DB0122210028810_,2.602327323,0.31061494,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,budesonide,DB01222
,13296,DB00108,10042609,65,10129,20,3275,0.89996285,1.050784753,0.627232369,1.834563299,0.956571579,DB0010810042609_,0.044399659,0.049537269,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,natalizumab,DB00108
,13298,DB00115,10031161,98,18327,18,10454,9.26677228511985e-07,3.105486762,1.864775561,5.46017665,1.34017666857978e-05,DB0011510031161_,11.22012402,1.13317047,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,13299,DB00404,10031161,71,19821,15,9847,0.001765346,2.351444773,1.333467172,4.422378117,0.008771669,DB0040410031161_,4.736228155,0.855029936,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,13302,DB01222,10031161,43,9231,10,5395,0.006291704,2.512969003,1.242175222,5.612929401,0.024598755,DB0122210031161_,3.705059436,0.921464924,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,budesonide,DB01222
,13314,DB00005,10053615,50,128032,18,42401,0.779178429,0.919922256,0.527369767,1.675618152,0.879672513,DB0000510053615_,0.128205585,-0.083466116,NA,10053615,Thermal burn,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,13315,DB00374,10002034,345,17371,84,5640,0.019894754,1.333470546,1.045613982,1.71676856,0.061503511,DB0037410002034_,2.78866101,0.287784977,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,treprostinil,DB00374
,13316,DB00203,10064911,811,13067,286,8652,9.49836747515017e-21,1.877510372,1.634132898,2.161880303,1.08314355351116e-18,DB0020310064911_,41.36666416,0.629946629,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,13317,DB00512,10014950,26,4711,66,5032,0.00013379,0.420841949,0.256052687,0.673090108,0.001021691,DB0051210014950_,6.88629641,-0.865497935,NA,10014950,Eosinophilia,10005329,Blood and lymphatic system disorders,Blood,vancomycin,DB00512
,13318,DB00264,10069327,156,29451,105,24787,0.081180965,1.250423213,0.969535031,1.618112874,0.180390706,DB0026410069327_,1.712630194,0.223482064,NA,10069327,Product quality issue,10077536,Product issues,Prod,metoprolol,DB00264
,13320,DB00620,10020751,69,4759,33,3099,0.154253406,1.361521759,0.884439256,2.134193394,0.289868048,DB0062010020751_,1.238329468,0.308603014,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,triamcinolone,DB00620
,13321,DB00374,10038683,63,17653,20,5704,1,1.017825176,0.606548806,1.778997858,1,DB0037410038683_,0,0.01766817,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,13322,DB00559,10038683,49,9610,24,3282,0.176950118,0.697289698,0.41892526,1.190272147,0.319975704,DB0055910038683_,1.139510211,-0.360554319,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,13323,DB00682,10038683,45,19414,23,16341,0.051695167,1.64680154,0.975102081,2.85297268,0.128237776,DB0068210038683_,2.053869111,0.498834946,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,13324,DB00374,10052251,77,17639,16,5708,0.116017125,1.557261648,0.899857083,2.862045296,0.235201892,DB0037410052251_,1.447311017,0.442928925,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,13326,DB00682,10052251,54,19405,21,16343,0.002340096,2.165578262,1.285870346,3.776664984,0.011055888,DB0068210052251_,4.504792105,0.772687421,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,13328,DB00005,10040849,107,127975,53,42366,0.021724116,0.668346303,0.476426033,0.947533561,0.065999758,DB0000510040849_,2.71810421,-0.402948822,NA,10040849,Skin fissures,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,13329,DB00381,10007559,290,29070,230,22657,0.859038615,0.982711165,0.822954174,1.174569354,0.933127944,DB0038110007559_,0.069212956,-0.017440032,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,amlodipine,DB00381
,13331,DB01132,10007559,49,1236,47,1483,0.298086516,1.250789174,0.814732924,1.922061041,0.464019667,DB0113210007559_,0.767828342,0.223774691,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,pioglitazone,DB01132
,13338,DB00222,10008190,28,3178,58,3070,0.000723063,0.466409637,0.285201322,0.746595442,0.004206663,DB0022210008190_,5.471085579,-0.762690981,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,glimepiride,DB00222
,13345,DB00222,10011906,111,3095,162,2966,0.000813981,0.656674817,0.50827745,0.84588788,0.004645136,DB0022210011906_,5.371934697,-0.420566335,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,13347,DB01132,10011906,25,1260,55,1475,0.008748603,0.532221837,0.315844329,0.874499625,0.0320007,DB0113210011906_,3.441997501,-0.63069489,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pioglitazone,DB01132
,13350,DB00331,10025082,50,24896,37,20715,0.666662492,1.1243818,0.72015613,1.769906109,0.797361892,DB0033110025082_,0.226446636,0.117233374,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,13351,DB00381,10025082,66,29294,58,22829,0.526541632,0.886800132,0.61342311,1.285009081,0.684323279,DB0038110025082_,0.379324843,-0.120135653,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,13359,DB00222,10035598,23,3183,30,3098,0.334816595,0.746230581,0.412958727,1.331987194,0.503974471,DB0022210035598_,0.685229665,-0.292720636,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glimepiride,DB00222
,13364,DB00331,10044390,78,24868,78,20674,0.260035671,0.831355381,0.599196686,1.153460299,0.421330721,DB0033110044390_,0.864337194,-0.184697921,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,metformin,DB00331
,13365,DB00381,10044390,94,29266,72,22815,0.937675485,1.017777484,0.740411265,1.404025826,0.977582109,DB0038110044390_,0.022672992,0.017621313,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,13370,DB00734,10007515,80,3970,51,4851,0.00026956,1.916562443,1.328737001,2.786510617,0.00184852,DB0073410007515_,6.29336984,0.650533187,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,risperidone,DB00734
,13371,DB00734,10012218,53,3997,36,4866,0.007269099,1.792159944,1.149217314,2.823650262,0.027577148,DB0073410012218_,3.590767823,0.583421565,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,13372,DB00734,10021097,70,3980,89,4813,0.809554098,0.951126993,0.683305457,1.319604917,0.897384007,DB0073410021097_,0.108271407,-0.050107689,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,risperidone,DB00734
,13378,DB00736,10008190,77,10514,62,5491,0.012058283,0.6486046,0.457434751,0.922939838,0.041302056,DB0073610008190_,3.186842991,-0.432931993,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,13380,DB00736,10044390,33,10558,20,5533,0.664244638,0.864709835,0.481174873,1.591868768,0.795574151,DB0073610044390_,0.228691223,-0.145361279,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,13384,DB01164,10061024,84,6440,151,7785,0.003596659,0.672492874,0.507657745,0.885806617,0.015655907,DB0116410061024_,4.156906987,-0.396763763,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,calcium chloride,DB01164
,13386,DB00169,10022437,749,37942,293,17882,0.007291486,1.204761888,1.049895107,1.385399901,0.027644125,DB0016910022437_,3.588342067,0.186281944,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,13387,DB00186,10022437,382,16519,172,9836,0.002499516,1.32240748,1.099727574,1.595368776,0.01165613,DB0018610022437_,4.451923098,0.279453924,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,13388,DB00203,10022437,276,13602,130,8808,0.002891772,1.374783132,1.110058001,1.709831309,0.013116518,DB0020310022437_,4.333882907,0.318295996,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,sildenafil,DB00203
,13390,DB00635,10022437,411,32642,258,23536,0.082988269,1.148591161,0.979692902,1.348628187,0.183398911,DB0063510022437_,1.696091655,0.138536114,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,13391,DB00737,10022437,58,2743,15,917,0.415779523,1.292549982,0.718762056,2.468125388,0.585004671,DB0073710022437_,0.536135447,0.256616997,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,meclizine,DB00737
,13392,DB00829,10022437,198,7854,113,4341,0.810509847,0.968445741,0.762403585,1.235129922,0.898079898,DB0082910022437_,0.107496242,-0.032062822,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,13393,DB00959,10022437,156,7922,72,4930,0.039063659,1.348324934,1.010995258,1.812618019,0.103768396,DB0095910022437_,2.265593828,0.298863032,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,methylprednisolone,DB00959
,13394,DB00996,10022437,683,38270,371,22054,0.38371476,1.060907576,0.932501703,1.208473552,0.553731503,DB0099610022437_,0.591075362,0.059124746,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,13395,DB06637,10022437,207,5955,59,1960,0.385505418,1.154739557,0.856626139,1.576753396,0.555644445,DB0663710022437_,0.587626677,0.143874827,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,dalfampridine,DB06637
,13399,DB00727,10019211,166,3677,98,4075,8.73193644459126e-07,1.87705854,1.447523694,2.444804575,1.27192546104783e-05,DB0072710019211_,11.2723936,0.629705945,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,13401,DB00727,10037844,108,3735,67,4106,0.000229886,1.771912704,1.289971264,2.448909,0.001619372,DB0072710037844_,6.425716763,0.572059587,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,nitroglycerin,DB00727
,13404,DB00669,10013700,279,6098,18,1079,3.40196566016705e-06,2.74237513,1.694169915,4.716540073,4.21497371564887e-05,DB0066910013700_,10.07428211,1.008824381,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,sumatriptan,DB00669
,13405,DB00759,10013700,799,195,103,103,6.24428497339064e-18,4.091465495,2.950515204,5.678338168,5.34628763926948e-16,DB0075910013700_,35.16495907,1.408903218,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,tetracycline,DB00759
,13408,DB00404,10010305,281,19611,113,9749,0.059406978,1.236155428,0.988855678,1.553953886,0.142382822,DB0040410010305_,1.94923592,0.212006102,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,13409,DB00472,10010305,128,10631,63,4249,0.197064964,0.812090518,0.594694807,1.118605861,0.345496253,DB0047210010305_,1.06277348,-0.208143469,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,13410,DB00788,10010305,69,9287,46,5015,0.28116183,0.810029281,0.548856105,1.20517668,0.445120684,DB0078810010305_,0.809409834,-0.210684883,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,naproxen,DB00788
,13411,DB01156,10010305,171,13451,82,6246,0.838430745,0.968372012,0.738594784,1.278176052,0.917014548,DB0115610010305_,0.086631942,-0.032138956,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,13412,DB05676,10010305,43,47086,34,25295,0.094867914,0.679387227,0.423138187,1.098839805,0.203012548,DB0567610010305_,1.594487491,-0.386564023,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,13413,DB00338,10019211,1762,31912,643,21629,8.78380155598049e-43,1.857251676,1.693051111,2.039420214,3.88037351090668e-40,DB0033810019211_,90.74747231,0.619097802,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,13414,DB00472,10019211,510,10249,107,4205,4.42223530444445e-11,1.955483621,1.579525419,2.43934677,1.53450105580623e-09,DB0047210019211_,20.29506055,0.670637539,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,13415,DB00788,10019211,530,8826,149,4912,3.23014564572723e-14,1.979542627,1.641729998,2.398334748,1.76884121454042e-12,DB0078810019211_,27.06069646,0.682865822,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,13416,DB01156,10019211,699,12923,180,6148,3.84886890242025e-14,1.847409203,1.561413412,2.194785803,2.07949679548029e-12,DB0115610019211_,26.89889518,0.613784227,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,13417,DB00338,10037153,365,33309,189,22083,0.005968502,1.280340204,1.070279025,1.535645944,0.023564714,DB0033810037153_,3.748004853,0.247125827,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,13418,DB00404,10037153,203,19689,57,9805,8.73490156185617e-05,1.773525764,1.314660913,2.425467804,0.000710826,DB0040410037153_,7.249082494,0.572969522,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,13419,DB00472,10037153,151,10608,33,4279,0.000978035,1.845680309,1.257230798,2.782825994,0.005408839,DB0047210037153_,5.219720729,0.612847941,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,fluoxetine,DB00472
,13420,DB00788,10037153,153,9203,60,5001,0.03574414,1.385665018,1.019419085,1.904267843,0.096979224,DB0078810037153_,2.333258512,0.326180182,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,naproxen,DB00788
,13421,DB01156,10037153,189,13433,52,6276,0.000611368,1.698079303,1.241341552,2.358331174,0.00365597,DB0115610037153_,5.611393886,0.529497791,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,bupropion,DB01156
,13422,DB05676,10037153,6310,40819,3429,21900,0.575758042,0.987283337,0.943932675,1.032750345,0.725180897,DB0567610037153_,0.321334142,-0.012798212,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,13423,DB00338,10046571,821,32853,238,22034,1.87339572739375e-33,2.313532988,1.998143541,2.686788653,5.21081552323225e-31,DB0033810046571_,69.72940151,0.838775788,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,13424,DB00472,10046571,210,10549,29,4283,1.24364462015779e-09,2.939741199,1.984005565,4.505464583,3.39981267195502e-08,DB0047210046571_,17.19696041,1.07832155,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,fluoxetine,DB00472
,13425,DB00788,10046571,194,9162,42,5019,4.97142289932892e-09,2.530202047,1.801113956,3.627948636,1.19391366750901e-07,DB0078810046571_,15.94085894,0.92829916,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,naproxen,DB00788
,13426,DB01156,10046571,203,13419,40,6288,6.9709322050573e-08,2.378004359,1.684898098,3.431800404,1.30552869975013e-06,DB0115610046571_,13.54890247,0.866261631,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,bupropion,DB01156
,13435,DB00332,10053762,59,2625,43,1613,0.410451803,0.8431583,0.556598351,1.286263656,0.579849861,DB0033210053762_,0.544986069,-0.170600557,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ipratropium,DB00332
,13436,DB06285,10053762,90,8760,24,1082,0.002248311,0.463232058,0.291110743,0.763603698,0.010700138,DB0628510053762_,4.537498684,-0.769527146,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,teriparatide,DB06285
,13439,DB00005,10023469,805,127277,257,42162,0.643479483,1.037630969,0.900150048,1.199285821,0.779830794,DB0000510023469_,0.248678314,0.036940201,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,13441,DB08908,10001760,236,10437,7,3272,1.5245617340509e-19,10.56856853,5.042943125,26.60783874,1.50934482785416e-17,DB0890810001760_,38.73227091,2.357884363,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,dimethyl fumarate,DB08908
,13457,DB00531,10014625,67,7185,80,6436,0.096441557,0.750214585,0.533060022,1.053026497,0.205410123,DB0053110014625_,1.582746697,-0.287395999,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,13460,DB00682,10001551,54,19405,33,16331,0.161641667,1.377128165,0.876504742,2.193579113,0.299608717,DB0068210001551_,1.205277932,0.320000291,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,warfarin,DB00682
,13461,DB00316,10003481,301,65173,253,36700,3.70417768450268e-06,0.66998556,0.564613485,0.795410275,4.54068443643761e-05,DB0031610003481_,9.999847707,-0.400499118,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,acetaminophen,DB00316
,13462,DB00682,10003481,65,19394,35,16329,0.034585006,1.563619673,1.020803006,2.431728969,0.094594737,DB0068210003481_,2.358153437,0.447003436,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,warfarin,DB00682
,13463,DB00682,10033295,80,19379,54,16310,0.224425266,1.246854461,0.871352964,1.796216292,0.379065552,DB0068210033295_,0.970046129,0.220623948,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,13464,DB00682,10037063,44,19415,54,16310,0.06747187,0.684517425,0.448766336,1.039058642,0.156807967,DB0068210037063_,1.852733361,-0.379041178,NA,10037063,Prothrombin time prolonged,10022891,Investigations,Inv,warfarin,DB00682
,13470,DB00563,10018867,34,46612,24,15324,0.005589042,0.46573472,0.268110882,0.821179961,0.022364869,DB0056310018867_,3.800263894,-0.764139078,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,methotrexate,DB00563
,13478,DB00404,10040753,242,19650,34,9828,2.05291155470766e-15,3.559758274,2.476891649,5.263338962,1.32581769571231e-13,DB0040410040753_,29.65157681,1.269692642,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,alprazolam,DB00404
,13479,DB00005,10035664,1606,126476,519,41900,0.649496581,1.025152049,0.927394058,1.134668382,0.784287431,DB0000510035664_,0.242979705,0.024840942,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,etanercept,DB00005
,13480,DB00658,10011906,96,1207,123,1273,0.18041048,0.823226169,0.616309917,1.097150522,0.324345232,DB0065810011906_,1.125946799,-0.194524306,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sevelamer,DB00658
,13481,DB06605,10011224,283,13790,150,12883,1.5459402255534e-08,1.762531885,1.438724094,2.166114288,3.32122934700217e-07,DB0660510011224_,14.91776065,0.566751346,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,13482,DB06605,10013968,949,13124,607,12426,1.4928467945352e-13,1.480247132,1.331476579,1.646544161,7.47418628463956e-12,DB0660510013968_,25.61956586,0.392209055,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,13483,DB06605,10037660,168,13905,162,12871,0.739554261,0.959908672,0.767888187,1.200274918,0.85016024,DB0660510037660_,0.16233043,-0.040917132,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,13490,DB00381,10030095,281,29079,145,22742,4.47425852174727e-05,1.515595776,1.235042526,1.866415817,0.000402071,DB0038110030095_,7.818880867,0.415808613,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,13494,DB00051,10003239,1195,24536,476,10944,0.041889458,1.119773105,1.003604525,1.250893667,0.109493279,DB0005110003239_,2.211892113,0.11312608,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,13495,DB05679,10003239,237,6694,126,4783,0.007991864,1.343945165,1.074646477,1.687203393,0.029760736,DB0567910003239_,3.514565324,0.295609441,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ustekinumab,DB05679
,13496,DB00051,10033425,576,25155,207,11213,0.008681384,1.240332308,1.054632758,1.463269602,0.03180598,DB0005110033425_,3.448100956,0.215379334,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,13497,DB05679,10033425,70,6861,35,4874,0.091687742,1.420742221,0.9322495,2.200802788,0.197978928,DB0567910033425_,1.61959468,0.351179426,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ustekinumab,DB05679
,13498,DB00051,10046571,320,25411,47,11373,9.58996724967931e-16,3.047089486,2.236163455,4.236113513,6.41405315923208e-14,DB0005110046571_,30.37769991,1.114186868,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,adalimumab,DB00051
,13499,DB05679,10046571,65,6866,19,4890,0.000335439,2.436305056,1.440572224,4.308861451,0.00221366,DB0567910046571_,6.113107952,0.89048257,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ustekinumab,DB05679
,13513,DB01076,10002388,17,25730,35,25548,0.012359736,0.482287853,0.253302685,0.88450585,0.042144844,DB0107610002388_,3.166642917,-0.729214138,NA,10002388,Angina unstable,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,13516,DB00973,10011078,14,3837,40,2981,1.10497570555369e-05,0.271967325,0.13640547,0.51177674,0.000118283,DB0097310011078_,9.042434088,-1.302073349,male,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,ezetimibe,DB00973
,13517,DB00476,10028596,74,17183,45,6132,0.006404503,0.586858976,0.399286344,0.871039441,0.024940049,DB0047610028596_,3.691280371,-0.532970734,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,duloxetine,DB00476
,13518,DB00973,10028596,35,3816,64,2957,3.66888090068876e-05,0.423821005,0.271572081,0.651740214,0.000338671,DB0097310028596_,7.990481763,-0.85844407,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,ezetimibe,DB00973
,13519,DB01076,10028596,333,25414,440,25143,7.63300991757175e-05,0.748754888,0.646707296,0.866213053,0.000632415,DB0107610028596_,7.365964699,-0.289343602,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,13520,DB00973,10007559,44,3807,53,2968,0.038936295,0.647280534,0.422604651,0.987036729,0.103503288,DB0097310007559_,2.268151899,-0.434975486,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,ezetimibe,DB00973
,13521,DB00331,10037400,65,24881,38,20714,0.092011806,1.424038608,0.939610348,2.185399201,0.198435372,DB0033110037400_,1.617291814,0.353496925,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,13526,DB00193,10014625,83,19237,28,8674,0.217180805,1.336535341,0.860862342,2.132871454,0.370112096,DB0019310014625_,0.993949356,0.290080699,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,13527,DB00381,10014625,58,29302,54,22833,0.390998516,0.836956627,0.567441499,1.236194378,0.560840163,DB0038110014625_,0.578319328,-0.177983029,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,13529,DB00635,10014625,103,32950,98,23696,0.052927905,0.755854188,0.567302228,1.007587946,0.130532216,DB0063510014625_,2.036135215,-0.279906794,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,13530,DB01104,10014625,55,15408,28,7258,0.725006636,0.925289753,0.576342239,1.516309967,0.838736631,DB0110410014625_,0.17585853,-0.077648345,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,13536,DB00264,10022611,37,29570,31,24861,1,1.00347671,0.605587692,1.673208861,1,DB0026410022611_,0,0.003470681,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,13538,DB00316,10022611,78,65396,37,36916,0.437207916,1.189995376,0.794721655,1.811105329,0.605671448,DB0031610022611_,0.501417604,0.173949421,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,13541,DB00635,10022611,127,32926,81,23713,0.438715123,1.129224096,0.847414037,1.511948957,0.60703956,DB0063510022611_,0.499161317,0.121530756,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,13542,DB00695,10022611,88,27961,32,20496,0.000560768,2.015765931,1.330536227,3.12430203,0.003393137,DB0069510022611_,5.68600053,0.700999238,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,13557,DB00186,10038695,172,16729,150,9858,0.000599709,0.675738979,0.538863554,0.848072667,0.003594841,DB0018610038695_,5.628255636,-0.391948404,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,13558,DB00264,10038695,235,29372,224,24668,0.187673014,0.881093088,0.729982893,1.063682123,0.333663909,DB0026410038695_,1.097621053,-0.126591997,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,13559,DB00295,10038695,145,14518,107,9495,0.364769775,0.88628967,0.684678135,1.150288942,0.534387111,DB0029510038695_,0.626634775,-0.120711441,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,13560,DB00331,10038695,122,24824,194,20558,1.13509881767145e-08,0.520809718,0.411470952,0.657060551,2.52527062399443e-07,DB0033110038695_,15.19174742,-0.652370529,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,13561,DB00448,10038695,38,5107,39,3085,0.024289657,0.588648065,0.365570168,0.946966604,0.07192628,DB0044810038695_,2.632113574,-0.529926787,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lansoprazole,DB00448
,13562,DB00635,10038695,388,32665,422,23372,3.61846938609823e-09,0.657877295,0.571069424,0.75770583,8.95166755892631e-08,DB0063510038695_,16.22884091,-0.418736847,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,13564,DB01050,10038695,89,18019,56,9315,0.254295247,0.821607918,0.58101426,1.170333841,0.414894048,DB0105010038695_,0.879732097,-0.196491983,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,13565,DB06228,10038695,100,15812,93,15983,0.613388562,1.086871893,0.810533977,1.45868365,0.755118767,DB0622810038695_,0.280880235,0.083303747,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,13566,DB01050,10003239,543,17565,194,9177,4.68504304279071e-06,1.462328602,1.236413072,1.735279696,5.58740273955326e-05,DB0105010003239_,9.792410912,0.380030098,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,13570,DB01050,10022093,97,18011,13,9358,1.46433319410208e-07,3.876517478,2.162470033,7.545971803,2.56599986713155e-06,DB0105010022093_,12.87316234,1.354937193,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,13571,DB01611,10022093,134,11779,15,2346,0.034468786,1.77916438,1.038560024,3.273792767,0.094351893,DB0161110022093_,2.360723944,0.576143805,NA,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,13572,DB01050,10022094,43,18065,12,9359,0.063467006,1.856392491,0.961112617,3.869249695,0.14971777,DB0105010022094_,1.89900329,0.618635083,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,13573,DB01611,10022094,60,11853,6,2355,0.132886373,1.986750254,0.85986014,5.634601368,0.259793105,DB0161110022094_,1.347869713,0.686500265,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,13574,DB01050,10023230,47,18061,15,9356,0.108343594,1.623109857,0.891170247,3.12697479,0.223550621,DB0105010023230_,1.498117398,0.484343974,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,13575,DB01611,10023230,61,11852,18,2343,0.13085381,0.66996596,0.38984437,1.206923393,0.256985386,DB0161110023230_,1.358736061,-0.400528373,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,13576,DB00005,10034960,70,128012,18,42401,0.38870843,1.288091185,0.758703638,2.298530997,0.558598223,DB0000510034960_,0.582324807,0.253161421,NA,10034960,Photophobia,10015919,Eye disorders,Eye,etanercept,DB00005
,13579,DB01050,10040831,36,18072,19,9352,1,0.980488424,0.54737267,1.810639352,1,DB0105010040831_,0,-0.01970444,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,13581,DB01050,10047513,157,17951,68,9303,0.230432428,1.196502499,0.893635982,1.616581839,0.38644213,DB0105010047513_,0.950773151,0.179402717,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ibuprofen,DB01050
,13582,DB01611,10047513,80,11833,13,2348,0.577157058,1.221079375,0.673642064,2.396670278,0.726267905,DB0161110047513_,0.319836317,0.199735201,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,hydroxychloroquine,DB01611
,13583,DB01050,10048959,287,17821,87,9284,6.06241977479265e-06,1.718532593,1.345630061,2.213242158,6.99827421082234e-05,DB0105010048959_,9.567261888,0.541470783,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,13587,DB01050,10052904,139,17969,47,9324,0.010355874,1.534577957,1.09400557,2.186364808,0.036607091,DB0105010052904_,3.307513313,0.428255397,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,13588,DB01611,10052904,161,11752,27,2334,0.488917233,1.184257386,0.782186523,1.857100127,0.652394317,DB0161110052904_,0.427106119,0.1691159,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,13589,DB08895,10013968,566,27548,119,6527,0.259010267,1.126915567,0.921472888,1.387653321,0.420084558,DB0889510013968_,0.867299259,0.119484314,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,13592,DB00065,10000081,134,9330,63,4894,0.497549233,1.115683191,0.819262973,1.533287398,0.65965961,DB0006510000081_,0.41603132,0.109466944,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,infliximab,DB00065
,13593,DB00563,10000081,380,46266,203,15145,5.71544394990501e-08,0.612772029,0.514885658,0.730975317,1.09020641671446e-06,DB0056310000081_,13.72914351,-0.489762307,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,13598,DB01067,10061024,21,4340,40,4783,0.05279495,0.578624339,0.323569651,1.006854303,0.130301903,DB0106710061024_,2.037901188,-0.547101822,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,glipizide,DB01067
,13610,DB00412,10034474,44,1020,43,1343,0.186727461,1.347105752,0.857231702,2.118293939,0.332394102,DB0041210034474_,1.101433961,0.297958403,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,rosiglitazone,DB00412
,13619,DB00904,10005287,33,23036,23,14433,0.682902693,0.898954697,0.511908656,1.604048548,0.80828987,DB0090410005287_,0.212834535,-0.106522639,NA,10005287,Blood albumin decreased,10022891,Investigations,Inv,ondansetron,DB00904
,13622,DB00136,10005395,57,2035,15,1667,3.40269011462287e-05,3.111880836,1.730728019,5.940726403,0.00031705,DB0013610005395_,8.056452134,1.135227314,female,10005395,Blood calcium decreased,10022891,Investigations,Inv,calcitriol,DB00136
,13624,DB00213,10005395,32,18863,20,13401,0.675865482,1.136658512,0.630173709,2.098086649,0.803554995,DB0021310005395_,0.218709652,0.128092828,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,13626,DB00381,10005395,39,29321,25,22862,0.528842815,1.216349013,0.717521189,2.097851842,0.686168703,DB0038110005395_,0.376631759,0.19585376,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,amlodipine,DB00381
,13629,DB00904,10005395,46,23023,16,14440,0.049184631,1.803167841,1.001539983,3.413419829,0.123456632,DB0090410005395_,2.091865341,0.58954503,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,ondansetron,DB00904
,13634,DB00213,10005425,53,18842,22,13399,0.034482145,1.713130689,1.023649908,2.959660194,0.094378423,DB0021310005425_,2.360442802,0.538322509,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,pantoprazole,DB00213
,13636,DB00381,10005425,66,29294,36,22851,0.089657837,1.430093542,0.938489244,2.211103814,0.194675849,DB0038110005425_,1.636419418,0.357739856,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,amlodipine,DB00381
,13637,DB00641,10005425,54,14070,40,12435,0.409606454,1.193114903,0.777515733,1.84454876,0.579046745,DB0064110005425_,0.546372071,0.176567452,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,simvastatin,DB00641
,13638,DB00722,10005425,83,25320,56,25976,0.017117557,1.520521243,1.069984659,2.174805854,0.054676751,DB0072210005425_,2.906316693,0.419053199,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,lisinopril,DB00722
,13642,DB00136,10005483,24,2068,36,1646,0.018041868,0.530723223,0.301603601,0.918558376,0.056941291,DB0013610005483_,2.865734526,-0.633514632,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,calcitriol,DB00136
,13643,DB00153,10005483,32,7391,25,3414,0.062211702,0.591273435,0.33890474,1.042475916,0.147584349,DB0015310005483_,1.913355407,-0.525476704,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,ergocalciferol,DB00153
,13645,DB00381,10005483,180,29180,202,22685,0.000418818,0.692761109,0.563054982,0.851805635,0.002660267,DB0038110005483_,5.929328706,-0.367070059,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,amlodipine,DB00381
,13646,DB00641,10005483,66,14058,94,12381,0.003166753,0.618387354,0.443972041,0.857042666,0.01414171,DB0064110005483_,4.258626666,-0.480640231,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,simvastatin,DB00641
,13647,DB00904,10005483,147,22922,130,14326,0.004329038,0.70674407,0.553793788,0.902690234,0.01821786,DB0090410005483_,4.005352824,-0.347086673,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,ondansetron,DB00904
,13648,DB01390,10005483,27,1382,34,1483,0.605109038,0.852200818,0.491731467,1.463658705,0.748273008,DB0139010005483_,0.289987383,-0.159933078,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,sodium bicarbonate,DB01390
,13661,DB00153,10005724,42,7381,12,3427,0.144919652,1.624984985,0.83855392,3.394982847,0.276932974,DB0015310005724_,1.283979774,0.485498576,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,ergocalciferol,DB00153
,13662,DB00213,10005724,129,18766,40,13381,1.40006856090598e-06,2.299496064,1.600430696,3.368616206,1.93790427190172e-05,DB0021310005724_,10.85131835,0.832689996,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,13664,DB00381,10005724,153,29207,77,22810,0.001689707,1.551796378,1.171825947,2.069368851,0.008463842,DB0038110005724_,4.771952099,0.439413213,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,amlodipine,DB00381
,13665,DB00641,10005724,66,14058,35,12440,0.016115195,1.668641759,1.090581744,2.592837045,0.052114653,DB0064110005724_,2.954309126,0.512009978,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,simvastatin,DB00641
,13666,DB00904,10005724,140,22929,40,14416,3.45625082694748e-06,2.200483824,1.53765654,3.212760625,4.27370753043966e-05,DB0090410005724_,10.06044374,0.788677256,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,ondansetron,DB00904
,13671,DB00213,10005851,39,18856,31,13390,0.629942658,0.893379839,0.542867373,1.481688758,0.768943403,DB0021310005851_,0.26273791,-0.112743437,NA,10005851,Blood urea increased,10022891,Investigations,Inv,pantoprazole,DB00213
,13673,DB00381,10005851,51,29309,47,22840,0.41648996,0.845610065,0.557442063,1.285206935,0.585706415,DB0038110005851_,0.534936614,-0.167696942,NA,10005851,Blood urea increased,10022891,Investigations,Inv,amlodipine,DB00381
,13675,DB00722,10005851,46,25357,67,25965,0.073258119,0.703037016,0.472051426,1.038990365,0.166941754,DB0072210005851_,1.790110309,-0.352345734,NA,10005851,Blood urea increased,10022891,Investigations,Inv,lisinopril,DB00722
,13676,DB00904,10005851,39,23030,32,14424,0.272892881,0.763338691,0.465769061,1.259280949,0.435875756,DB0090410005851_,0.830398039,-0.270053452,NA,10005851,Blood urea increased,10022891,Investigations,Inv,ondansetron,DB00904
,13679,DB00153,10013911,44,7379,21,3418,0.89426265,0.970499996,0.563845682,1.721152189,0.955897633,DB0015310013911_,0.04510445,-0.029943881,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,13680,DB00213,10013911,90,18805,91,13330,0.01886945,0.701084794,0.517536029,0.949597516,0.059028827,DB0021310013911_,2.829729368,-0.355126438,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,13682,DB00381,10013911,180,29180,169,22718,0.083380999,0.829227875,0.667973103,1.029818738,0.184103228,DB0038110013911_,1.692258659,-0.187260282,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,13683,DB00641,10013911,88,14036,97,12378,0.139371636,0.800061287,0.591995224,1.080026884,0.268975979,DB0064110013911_,1.313133199,-0.223066945,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,13684,DB00904,10013911,173,22896,92,14364,0.20590003,1.179660279,0.910046113,1.537600253,0.356339365,DB0090410013911_,1.03187173,0.165226498,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,13688,DB00153,10013950,71,7352,21,3418,0.071857447,1.571770356,0.952685708,2.698055975,0.164529051,DB0015310013950_,1.804668123,0.452202599,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,13690,DB00381,10013950,166,29194,103,22784,0.073872243,1.257781015,0.977129112,1.62545736,0.167962624,DB0038110013950_,1.784013803,0.229349069,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,13691,DB00641,10013950,105,14019,92,12383,1,1.008115605,0.753869095,1.35007037,1,DB0064110013950_,0,0.00808285,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,13692,DB00904,10013950,191,22878,114,14342,0.723089289,1.050319942,0.827722672,1.337736941,0.837138917,DB0090410013950_,0.177765252,0.049094825,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,13702,DB00904,10016165,61,23008,65,14391,0.00321199,0.587017943,0.406750035,0.846195903,0.014302414,DB0090410016165_,4.247326924,-0.532699892,NA,10016165,Failure to thrive,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,13704,DB00136,10016256,102,1990,84,1598,0.879952777,0.975088284,0.717624572,1.327839388,0.949586729,DB0013610016256_,0.051728412,-0.025227264,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,calcitriol,DB00136
,13705,DB00153,10016256,552,6871,253,3186,0.906001372,1.011681918,0.864920448,1.185733119,0.958049888,DB0015310016256_,0.042855427,0.011614211,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,13706,DB00258,10016256,38,640,31,712,0.218762232,1.363402693,0.815382489,2.295225868,0.372010433,DB0025810016256_,0.98883338,0.309983555,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,calcium acetate,DB00258
,13707,DB00381,10016256,1949,27411,1245,21642,1.26806217363154e-08,1.235984043,1.147994278,1.331054145,2.7869032016825e-07,DB0038110016256_,15.09316464,0.211867449,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,13708,DB00641,10016256,914,13210,769,11706,0.31282103,1.053249906,0.952779959,1.164551789,0.480342375,DB0064110016256_,0.733256149,0.051880533,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,13709,DB01390,10016256,54,1355,66,1451,0.514311865,0.876188902,0.595152896,1.285224339,0.674282377,DB0139010016256_,0.394106298,-0.13217357,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sodium bicarbonate,DB01390
,13710,DB00136,10018884,36,2056,37,1645,0.341561529,0.778530292,0.475780935,1.272802087,0.510763464,DB0013610018884_,0.671848684,-0.250347377,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,calcitriol,DB00136
,13711,DB00153,10018884,85,7338,55,3384,0.054855074,0.712711581,0.500495892,1.02216171,0.13407405,DB0015310018884_,2.009363018,-0.338678455,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ergocalciferol,DB00153
,13712,DB00213,10018884,302,18593,229,13192,0.450779817,0.9356937,0.784225786,1.117565431,0.618454893,DB0021310018884_,0.48053102,-0.066467099,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,13714,DB00381,10018884,333,29027,273,22614,0.537061415,0.950322424,0.806549456,1.120456923,0.693252585,DB0038110018884_,0.366360866,-0.050953958,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,amlodipine,DB00381
,13715,DB00641,10018884,162,13962,122,12353,0.188726024,1.174835604,0.921888349,1.500358398,0.334942341,DB0064110018884_,1.093796878,0.161128226,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,simvastatin,DB00641
,13716,DB00722,10018884,242,25161,215,25817,0.132641474,1.154923373,0.956314758,1.395498635,0.259507343,DB0072210018884_,1.348970282,0.144033998,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,lisinopril,DB00722
,13717,DB00904,10018884,349,22720,175,14281,0.016506187,1.253510002,1.041143767,1.513687287,0.053111166,DB0090410018884_,2.93536809,0.225947618,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ondansetron,DB00904
,13719,DB00136,10020772,42,2050,23,1659,0.16573674,1.477642939,0.864502406,2.585265303,0.305113985,DB0013610020772_,1.18706985,0.390448209,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,calcitriol,DB00136
,13720,DB00153,10020772,120,7303,33,3406,0.006511673,1.695866389,1.142573732,2.580233869,0.025278295,DB0015310020772_,3.677809154,0.528193754,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ergocalciferol,DB00153
,13721,DB00213,10020772,233,18662,157,13264,0.641833243,1.054812628,0.856754224,1.301467323,0.778414931,DB0021310020772_,0.250495567,0.053363147,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,pantoprazole,DB00213
,13723,DB00381,10020772,597,28763,381,22506,0.001992924,1.226059478,1.075063194,1.399590253,0.009695653,DB0038110020772_,4.636077608,0.20380535,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,13724,DB00641,10020772,172,13952,146,12329,0.734800562,1.041046215,0.828956339,1.30876439,0.846669856,DB0064110020772_,0.16644444,0.040226184,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,simvastatin,DB00641
,13725,DB00904,10020772,289,22780,163,14293,0.285192685,1.112466179,0.913874113,1.357926416,0.449777565,DB0090410020772_,0.799002118,0.106579333,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ondansetron,DB00904
,13727,DB00016,10030095,30,2732,20,2270,0.478219899,1.246284921,0.682628664,2.322189458,0.643526854,DB0001610030095_,0.440791522,0.220167063,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,13729,DB00153,10030095,60,7363,23,3416,0.478950062,1.2102418,0.735753892,2.054817778,0.644146663,DB0015310030095_,0.439828842,0.190820175,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,13730,DB00213,10030095,128,18767,70,13351,0.082527684,1.300849825,0.96373925,1.768231505,0.182580606,DB0021310030095_,1.700563527,0.263017762,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,13732,DB00641,10030095,83,14041,55,12420,0.104279371,1.334853025,0.937199973,1.914241978,0.217469554,DB0064110030095_,1.525696419,0.288821192,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,13733,DB00722,10030095,148,25255,111,25921,0.01268001,1.368480467,1.062019255,1.767613694,0.043008459,DB0072210030095_,3.146358454,0.313700976,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,13734,DB00904,10030095,139,22930,55,14401,0.003803791,1.587213433,1.152777162,2.211867798,0.016377175,DB0090410030095_,4.111866679,0.461979921,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,13737,DB00153,10038153,40,7383,18,3421,1,1.029717695,0.575908603,1.911101011,1,DB0015310038153_,0,0.029284682,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,ergocalciferol,DB00153
,13738,DB00213,10038153,89,18806,58,13363,0.675054264,1.090376306,0.773983676,1.54628673,0.802959604,DB0021310038153_,0.219450872,0.086522871,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,13740,DB00381,10038153,113,29247,63,22824,0.033103586,1.399732391,1.019084564,1.937485792,0.091510519,DB0038110038153_,2.391301351,0.336281069,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,amlodipine,DB00381
,13741,DB00641,10038153,47,14077,43,12432,0.915884055,0.965285098,0.624129727,1.496333926,0.96236383,DB0064110038153_,0.038362698,-0.035331783,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,simvastatin,DB00641
,13742,DB00722,10038153,87,25316,72,25960,0.203608602,1.239063638,0.895828923,1.718320748,0.353409193,DB0072210038153_,1.040128707,0.214355963,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,lisinopril,DB00722
,13743,DB00904,10038153,145,22924,74,14382,0.163664203,1.229284018,0.922039761,1.650686297,0.302323594,DB0090410038153_,1.196257331,0.206431901,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,ondansetron,DB00904
,13747,DB00153,10043071,38,7385,18,3421,1,0.977944824,0.543685121,1.823165256,1,DB0015310043071_,0,-0.022302027,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,ergocalciferol,DB00153
,13748,DB00213,10043071,115,18780,90,13331,0.522375488,0.90703548,0.681727856,1.209929806,0.680961055,DB0021310043071_,0.384250162,-0.097573712,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,13750,DB00381,10043071,130,29230,110,22777,0.557434528,0.920914442,0.708449797,1.198888736,0.710528651,DB0038110043071_,0.341746007,-0.082388143,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,amlodipine,DB00381
,13751,DB00641,10043071,40,14084,32,12443,0.723575225,1.104325176,0.676000533,1.817491522,0.837498615,DB0064110043071_,0.177335669,0.099234448,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,simvastatin,DB00641
,13752,DB00722,10043071,97,25306,98,25934,0.942876,1.014360321,0.757706842,1.357843276,0.981842735,DB0072210043071_,0.018324131,0.014258188,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,lisinopril,DB00722
,13753,DB00904,10043071,163,22906,160,14296,5.56263645395928e-05,0.635848748,0.507531692,0.796646837,0.000483672,DB0090410043071_,7.634104568,-0.452794561,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,ondansetron,DB00904
,13755,DB00016,10047700,91,2671,51,2239,0.025910365,1.495603931,1.044884874,2.160992777,0.075494058,DB0001610047700_,2.583701322,0.402530093,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,erythropoietin,DB00016
,13756,DB00136,10047700,89,2003,49,1633,0.029366232,1.480656174,1.026534605,2.157132729,0.083303627,DB0013610047700_,2.485263185,0.392485351,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,calcitriol,DB00136
,13757,DB00153,10047700,278,7145,77,3362,2.76045645845258e-05,1.69875343,1.310672718,2.223633112,0.000263706,DB0015310047700_,8.240677199,0.529894706,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,13758,DB00213,10047700,723,18172,325,13096,1.00750286666657e-12,1.603186875,1.401757306,1.836645727,4.51557307186866e-11,DB0021310047700_,23.82090392,0.471993445,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,13760,DB00722,10047700,850,24553,527,25505,1.32514979884337e-20,1.67541074,1.498954489,1.874070424,1.47904723832688e-18,DB0072210047700_,41.05513355,0.516058353,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,13761,DB01390,10047700,67,1342,41,1476,0.004233457,1.796942847,1.191351611,2.739029798,0.017885788,DB0139010047700_,4.023748867,0.586086802,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sodium bicarbonate,DB01390
,13782,DB00016,10061428,78,2684,65,2225,1,0.994784598,0.702955362,1.411680196,1,DB0001610061428_,0,-0.00522905,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,erythropoietin,DB00016
,13783,DB00136,10061428,30,2062,29,1653,0.510479079,0.829336362,0.478814834,1.438361166,0.670880358,DB0013610061428_,0.399164462,-0.187129462,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,calcitriol,DB00136
,13784,DB00153,10061428,128,7295,75,3364,0.109647943,0.78705369,0.585453976,1.064292504,0.225542605,DB0015310061428_,1.489246201,-0.239458812,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ergocalciferol,DB00153
,13785,DB00213,10061428,382,18513,258,13163,0.543534071,1.052747809,0.895100144,1.239681401,0.698699217,DB0021310061428_,0.358534934,0.051403707,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,13787,DB00381,10061428,625,28735,413,22474,0.008707244,1.183579866,1.042247297,1.345184195,0.031887136,DB0038110061428_,3.445552598,0.16854363,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,13788,DB00904,10061428,633,22436,438,14018,0.111197944,0.902967766,0.796641294,1.024186768,0.227883827,DB0090410061428_,1.478919311,-0.102068422,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,13790,DB00051,10028810,239,25492,96,11324,0.439489911,1.105911564,0.868193557,1.418016835,0.60790361,DB0005110028810_,0.497738946,0.10066994,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,adalimumab,DB00051
,13791,DB00065,10028810,41,9423,17,4940,0.489278317,1.264391649,0.701776608,2.376206441,0.652627654,DB0006510028810_,0.42674852,0.234591097,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,infliximab,DB00065
,13792,DB00051,10040844,77,25654,61,11359,0.000837221,0.558950165,0.393944854,0.796023114,0.004754018,DB0005110040844_,5.348765194,-0.58169496,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,13794,DB01164,10005555,26,6498,34,7902,0.79665291,0.929918769,0.535275572,1.598114809,0.889928676,DB0116410005555_,0.116613959,-0.072658042,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,calcium chloride,DB01164
,13795,DB01164,10016173,117,6407,135,7801,0.701748804,1.055261305,0.814794684,1.364933244,0.820985212,DB0116410016173_,0.197250182,0.053788419,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium chloride,DB01164
,13797,DB00051,10008531,134,25597,67,11353,0.443464687,0.887066799,0.656179061,1.208922939,0.611583163,DB0005110008531_,0.491704334,-0.11983499,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,13799,DB01373,10008531,192,22528,51,7330,0.230684585,1.224919116,0.894234561,1.704547232,0.386728035,DB0137310008531_,0.950033585,0.202874814,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,13801,DB00451,10008796,68,47203,31,15388,0.128814705,0.715092875,0.460966611,1.132091457,0.253929392,DB0045110008796_,1.370699033,-0.33534285,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,13804,DB00051,10012735,698,25033,320,11100,0.629768449,0.967220874,0.844483499,1.109633095,0.768820013,DB0005110012735_,0.262898391,-0.033328398,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,13805,DB00993,10012735,159,3090,67,1552,0.24813641,1.191875299,0.884250509,1.621190117,0.407488789,DB0099310012735_,0.897741859,0.175527948,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,azathioprine,DB00993
,13806,DB00051,10022086,813,24918,244,11176,2.2388689552034e-08,1.494409312,1.291296552,1.734467383,4.63923299073877e-07,DB0005110022086_,14.5835466,0.40173102,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,13807,DB00451,10022086,517,46754,85,15334,2.67268502564685e-10,1.994941088,1.581950831,2.541776438,8.17353413602415e-09,DB0045110022086_,18.62236445,0.69061452,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,13809,DB01373,10022086,223,22497,27,7354,5.16072740671124e-08,2.699915709,1.804373182,4.192158843,9.95594274388292e-07,DB0137310022086_,13.81992602,0.993220554,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,13810,DB00051,10033645,63,25668,38,11382,0.132175557,0.73515386,0.483590947,1.131055415,0.25890413,DB0005110033645_,1.351297441,-0.307675469,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,13812,DB00451,10033645,146,47125,52,15367,0.564002223,0.915552487,0.662508627,1.282691835,0.715879877,DB0045110033645_,0.334242895,-0.088227585,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,13813,DB01373,10033645,47,22673,19,7362,0.394057867,0.803213424,0.462098504,1.45023338,0.56401269,DB0137310033645_,0.572678528,-0.219134817,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,13814,DB00993,10037660,91,3158,73,1546,0.00234273,0.610312577,0.440788512,0.847509418,0.011063359,DB0099310037660_,4.504116632,-0.493784032,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,azathioprine,DB00993
,13815,DB00203,10044390,31,13847,27,8911,0.281480462,0.738895665,0.426424708,1.287637173,0.445423916,DB0020310044390_,0.80872883,-0.302598552,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,13817,DB00682,10044390,76,19383,103,16261,0.001538032,0.619033153,0.453737997,0.841354338,0.00785375,DB0068210044390_,4.846764211,-0.479596449,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,13818,DB00243,10016173,50,1204,52,1574,0.264706048,1.256918546,0.828794621,1.904603433,0.426665708,DB0024310016173_,0.851754459,0.228663127,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ranolazine,DB00243
,13819,DB00661,10016173,96,3432,30,1565,0.079379241,1.45910754,0.954762604,2.288422569,0.177391884,DB0066110016173_,1.729393959,0.377824975,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,verapamil,DB00661
,13820,DB00973,10016173,115,3736,80,2941,0.421363675,1.131565082,0.839643528,1.531282942,0.590435306,DB0097310016173_,0.526895207,0.123601703,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ezetimibe,DB00973
,13822,DB00404,10020100,68,19824,9,9853,2.58582902486873e-05,3.754948321,1.865058952,8.565826445,0.00024865,DB0040410020100_,8.299463708,1.323074522,female,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,13823,DB00476,10020100,53,17204,22,6155,0.599429275,0.861914692,0.514790899,1.489531367,0.744067365,DB0047610020100_,0.295623703,-0.148598979,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,13824,DB00559,10020100,97,9562,13,3293,0.000583127,2.569655066,1.431854133,5.005590361,0.003511053,DB0055910020100_,5.65183922,0.943771674,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,bosentan,DB00559
,13826,DB00695,10020100,120,27929,72,20456,0.188249791,1.220709002,0.903376364,1.659481198,0.334345468,DB0069510020100_,1.095580485,0.199431839,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,13828,DB06228,10020100,40,15872,24,16052,0.045205565,1.685529954,0.991070197,2.924477768,0.115982629,DB0622810020100_,2.154314845,0.522080027,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,13834,DB00537,10017577,81,7476,46,4252,1,1.001500331,0.687552968,1.4742082,1,DB0053710017577_,0,0.001499206,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,13835,DB00537,10028411,97,7460,35,4263,0.022451334,1.583668797,1.06370696,2.406945182,0.067616626,DB0053710028411_,2.693901382,0.459744179,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ciprofloxacin,DB00537
,13839,DB00673,10012735,42,625,20,321,0.890009266,1.078487738,0.607369471,1.973504013,0.954404812,DB0067310012735_,0.046667366,0.075559817,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,aprepitant,DB00673
,13840,DB00673,10013968,68,599,18,323,0.008467884,2.035811565,1.172404439,3.703533282,0.031167041,DB0067310013968_,3.468394121,0.710894543,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,aprepitant,DB00673
,13841,DB00673,10028813,99,568,43,298,0.389171239,1.207664312,0.81178499,1.819771089,0.559069406,DB0067310028813_,0.581481652,0.188688174,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,aprepitant,DB00673
,13843,DB00673,10047700,56,611,22,319,0.31938634,1.328585338,0.781621982,2.329151677,0.487575208,DB0067310047700_,0.718310727,0.28411472,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,aprepitant,DB00673
,13856,DB01285,10012735,48,1228,8,601,0.003296604,2.935147033,1.365058993,7.230201828,0.014605395,DB0128510012735_,4.226364269,1.076757549,female,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,corticotropin,DB01285
,13857,DB01285,10033371,53,1223,14,595,0.045721132,1.84125183,0.997254905,3.623577989,0.11694448,DB0128510033371_,2.146055985,0.610445683,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,corticotropin,DB01285
,13860,DB08932,10012735,2133,17310,557,6040,3.06520505212604e-09,1.336251468,1.210995239,1.476131325,7.73214153504156e-08,DB0893210012735_,16.37529488,0.289868282,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,13861,DB08932,10005483,154,19289,46,6551,0.513735862,1.136993348,0.812089397,1.618869894,0.673695227,DB0893210005483_,0.394977456,0.128387365,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,macitentan,DB08932
,13863,DB00295,10020937,122,14541,66,9536,0.230991089,1.212203245,0.890233775,1.663252076,0.387133023,DB0029510020937_,0.948986917,0.192439568,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,morphine,DB00295
,13864,DB00327,10020937,94,6044,47,4215,0.070025387,1.39472749,0.970249522,2.028678028,0.161335456,DB0032710020937_,1.824269503,0.332699048,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,13865,DB00433,10020937,105,7551,39,5981,3.07298093810299e-05,2.132381873,1.461003844,3.168851268,0.000289718,DB0043310020937_,8.146603443,0.757239605,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,13866,DB00480,10020937,691,66737,480,67182,3.70956663655741e-10,1.449171133,1.287307626,1.632397144,1.11244676602295e-08,DB0048010020937_,18.31411886,0.37099176,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,13867,DB00787,10020937,216,16784,138,17110,1.7855213851539e-05,1.595586966,1.281361965,1.992360368,0.000180614,DB0078710020937_,8.619150921,0.467241672,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,13868,DB01234,10020937,432,31193,256,32632,3.16529294070448e-13,1.765318858,1.507790573,2.07023364,1.51962967938662e-11,DB0123410020937_,24.90996935,0.56833133,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,13869,DB01373,10020937,307,22413,64,7317,0.000816987,1.565927946,1.191145038,2.086300016,0.004659252,DB0137310020937_,5.368900344,0.448478585,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,calcium,DB01373
,13877,DB00497,10007617,446,18821,312,16063,0.007964248,1.220004505,1.051642753,1.416676002,0.029687336,DB0049710007617_,3.517034713,0.198854551,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,oxycodone,DB00497
,13879,DB00497,10022523,85,19182,77,16298,0.693488713,0.9379506,0.680407711,1.294691225,0.815421988,DB0049710022523_,0.204049523,-0.064057997,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,13880,DB00497,10042464,36,19231,49,16326,0.037827414,0.623727982,0.393823141,0.979404141,0.101303471,DB0049710042464_,2.289634602,-0.472040931,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,13884,DB01164,10005724,33,6491,22,7914,0.029632335,1.828737866,1.033532864,3.295909984,0.083890994,DB0116410005724_,2.478237008,0.603626038,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,calcium chloride,DB01164
,13885,DB01164,10007617,18,6506,36,7900,0.09953578,0.607153487,0.324249231,1.098736476,0.210102227,DB0116410007617_,1.560161072,-0.498973659,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,calcium chloride,DB01164
,13895,DB01267,10060933,34,2818,59,3656,0.206087193,0.747672414,0.473876312,1.162938248,0.3565459,DB0126710060933_,1.031292295,-0.290790347,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,13897,DB00374,10019196,72,17644,23,5701,1,1.011484591,0.624276331,1.697065542,1,DB0037410019196_,0,0.011419144,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,13898,DB00559,10019196,72,9587,21,3285,0.553148245,1.174787182,0.712823849,2.015007559,0.706785465,DB0055910019196_,0.347028103,0.161087009,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,bosentan,DB00559
,13899,DB00820,10019196,65,11850,21,5795,0.107156125,1.513630043,0.912215811,2.609765919,0.221849303,DB0082010019196_,1.505756941,0.414510768,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,tadalafil,DB00820
,13901,DB00370,10013700,136,4405,47,3616,1.03196029179296e-07,2.375030347,1.687685994,3.393927787,1.86362598899197e-06,DB0037010013700_,13.19298651,0.865010215,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,mirtazapine,DB00370
,13903,DB01060,10013700,1696,6891,340,4741,2.49193032357338e-105,3.431357162,3.034491072,3.889565781,4.67859918250902e-102,DB0106010013700_,233.3206807,1.232955857,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,amoxicillin,DB01060
,13905,DB00193,10010774,352,18968,160,8542,0.923246185,0.99074254,0.818072021,1.204074461,0.966487155,DB0019310010774_,0.034087271,-0.009300576,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,13906,DB00196,10010774,100,4983,53,3232,0.24360062,1.223733597,0.865834303,1.746564134,0.40198636,DB0019610010774_,0.911337122,0.201906511,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,fluconazole,DB00196
,13907,DB00316,10010774,1284,64190,737,36216,0.708281655,0.982940935,0.896293963,1.078601753,0.825760498,DB0031610010774_,0.191450501,-0.017206247,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,13908,DB00381,10010774,603,28757,369,22518,0.000197822,1.279601571,1.12089803,1.462313362,0.00142772,DB0038110010774_,6.551676273,0.246548757,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,13910,DB00531,10010774,115,7137,96,6420,0.626921696,1.077595701,0.812815172,1.431185017,0.766394753,DB0053110010774_,0.266057898,0.074732357,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,13911,DB00646,10010774,86,3367,50,1950,1,0.996139328,0.691634026,1.448003542,1,DB0064610010774_,0,-0.003868143,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,nystatin,DB00646
,13912,DB00697,10010774,109,5987,26,1780,0.352842857,1.246379702,0.80353983,1.99914849,0.522593931,DB0069710010774_,0.648950539,0.220243111,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,tizanidine,DB00697
,13913,DB01050,10010774,308,17800,133,9238,0.0850226,1.201833617,0.975959386,1.486541929,0.186815543,DB0105010010774_,1.67763355,0.183848405,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,13915,DB08910,10010774,380,16364,327,17161,0.009718413,1.218668362,1.046710564,1.419499715,0.034790395,DB0891010010774_,3.358413929,0.197758756,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,13916,DB00193,10012174,244,19076,97,8605,0.316966466,1.134690924,0.891944278,1.452954264,0.484782006,DB0019310012174_,0.724055961,0.1263603,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,tramadol,DB00193
,13917,DB00196,10012174,72,5011,68,3217,0.028745668,0.679803014,0.479651884,0.964278963,0.081923319,DB0019610012174_,2.501971607,-0.385952207,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,fluconazole,DB00196
,13919,DB00531,10012174,109,7143,96,6420,0.943841809,1.020493031,0.766818706,1.35990443,0.982646728,DB0053110012174_,0.017505605,0.020285874,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,cyclophosphamide,DB00531
,13920,DB00646,10012174,80,3373,43,1957,0.776602566,1.079428187,0.732737729,1.609289324,0.878242845,DB0064610012174_,0.129832135,0.076431444,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,nystatin,DB00646
,13921,DB00697,10012174,71,6025,16,1790,0.369658548,1.318308016,0.756291109,2.436532822,0.539279864,DB0069710012174_,0.617520616,0.276349109,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,tizanidine,DB00697
,13923,DB08910,10012174,172,16572,172,17316,0.704541622,1.044909627,0.839936654,1.299901761,0.8228966,DB0891010012174_,0.194924724,0.043930401,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,pomalidomide,DB08910
,13924,DB00193,10029148,69,19251,35,8667,0.595708514,0.887567943,0.582254733,1.37497769,0.74122358,DB0019310029148_,0.299452972,-0.119270205,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,tramadol,DB00193
,13926,DB00316,10029148,200,65274,126,36827,0.355395728,0.895545019,0.71275226,1.128737148,0.525132201,DB0031610029148_,0.644105237,-0.110322787,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,13927,DB00381,10029148,61,29299,72,22815,0.017992701,0.65974337,0.461032906,0.941443641,0.056846265,DB0038110029148_,2.867404761,-0.415904352,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,13932,DB01050,10029148,60,18048,37,9334,0.392954212,0.838680884,0.54722347,1.300668186,0.562967365,DB0105010029148_,0.574533618,-0.175924997,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,ibuprofen,DB01050
,13935,DB00060,10019211,396,9112,65,2400,0.000326034,1.604555992,1.226557287,2.12771048,0.00216,DB0006010019211_,6.137647217,0.472847078,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,13937,DB01015,10013700,1519,8368,293,9088,7.03837173461473e-203,5.6290035,4.946741584,6.424505355,5.28581717269566e-199,DB0101510013700_,456.5494063,1.727932428,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,sulfamethoxazole,DB01015
,13939,DB00005,10025310,76,128006,38,42381,0.03971917,0.662174149,0.442893873,1.005076289,0.105106049,DB0000510025310_,2.252785451,-0.412226692,NA,10025310,Lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,etanercept,DB00005
,13941,DB00169,10001760,644,38047,52,18123,2.93515177719209e-55,5.899455186,4.440115271,7.9887433,2.14306845731928e-52,DB0016910001760_,118.9721862,1.774860005,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,13942,DB00181,10001760,113,9743,13,5858,1.15281958679012e-11,5.225404397,2.932641526,10.12603417,4.36626265688448e-10,DB0018110001760_,21.55194351,1.653532191,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,baclofen,DB00181
,13943,DB00316,10001760,677,64797,99,36854,7.27638056709626e-49,3.889358988,3.144293773,4.85443216,4.2035090814533e-46,DB0031610001760_,104.4829946,1.35824436,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,13944,DB00476,10001760,172,17085,13,6164,2.24289037640532e-11,4.773380563,2.715740482,9.155284583,8.09257015014602e-10,DB0047610001760_,20.93490455,1.563054767,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,duloxetine,DB00476
,13945,DB00656,10001760,121,11892,16,6603,4.04384467583217e-10,4.198755669,2.480733881,7.586415929,1.20718293360873e-08,DB0065610001760_,18.23239125,1.434788212,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,trazodone,DB00656
,13947,DB01068,10001760,160,13603,8,6832,3.0163986010659e-19,10.04443527,4.972197376,23.67783951,2.936519897371e-17,DB0106810001760_,38.06672141,2.307018776,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,clonazepam,DB01068
,13948,DB00169,10003553,253,38438,33,18142,8.50608849114225e-16,3.618199379,2.509837526,5.372935919,5.7255450957663e-14,DB0016910003553_,30.49125354,1.285976493,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,13949,DB00181,10003553,43,9813,12,5859,0.017272544,2.139387986,1.107150793,4.460494795,0.055081445,DB0018110003553_,2.898942374,0.7605198,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,baclofen,DB00181
,13950,DB00316,10003553,327,65147,46,36907,3.87324149733147e-25,4.027162627,2.949958575,5.610933754,5.98081625585183e-23,DB0031610003553_,51.17090008,1.393062065,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,13951,DB00476,10003553,103,17154,9,6168,1.43510894580287e-06,4.11501332,2.083573093,9.26122083,1.9806688705922e-05,DB0047610003553_,10.82949086,1.414642071,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,13952,DB00656,10003553,63,11950,12,6607,0.000242232,2.902514272,1.549428207,5.917606004,0.001689104,DB0065610003553_,6.383557249,1.065577352,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,13954,DB01068,10003553,79,13684,13,6827,5.0062153945491e-05,3.031668607,1.673352938,5.947680427,0.000442388,DB0106810003553_,7.723322769,1.109113163,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,13956,DB01202,10048294,68,6646,81,5637,0.046853027,0.712077533,0.507083673,0.997318313,0.119184343,DB0120210048294_,2.127083886,-0.339568478,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,13958,DB00115,10002034,352,18073,235,10237,0.056277363,0.848444512,0.715921902,1.006897397,0.136594533,DB0011510002034_,1.990738358,-0.164350592,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,cyanocobalamin,DB00115
,13959,DB00126,10002034,214,9957,129,5816,0.777598456,0.968970917,0.773254371,1.218151569,0.878745262,DB0012610002034_,0.129260228,-0.031520681,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ascorbic acid,DB00126
,13960,DB00332,10002034,60,2624,25,1631,0.113888055,1.49163744,0.916907805,2.493331125,0.232003994,DB0033210002034_,1.461000692,0.39987447,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ipratropium,DB00332
,13962,DB00706,10002034,14,1061,295,15630,0.23670567,0.699108805,0.376167631,1.197376052,0.393993083,DB0070610002034_,0.931421926,-0.357948891,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,tamsulosin,DB00706
,13963,DB00722,10002034,420,24983,403,25629,0.342956257,1.069165034,0.929260719,1.230176994,0.512295355,DB0072210002034_,0.668853955,0.066878002,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,lisinopril,DB00722
,13964,DB00727,10002034,87,3756,97,4076,0.881497514,0.973319909,0.717675069,1.318320606,0.95045981,DB0072710002034_,0.050809401,-0.027042464,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,nitroglycerin,DB00727
,13965,DB00736,10002034,190,10401,92,5461,0.569367635,1.084335502,0.839073606,1.409575945,0.720261201,DB0073610002034_,0.328141353,0.080967359,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,esomeprazole,DB00736
,13966,DB01076,10002034,450,25297,441,25142,0.839389001,1.014157164,0.886318819,1.160478918,0.917718939,DB0107610002034_,0.085864101,0.014057887,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,atorvastatin,DB01076
,13967,DB01118,10002034,80,2983,87,4622,0.024983738,1.424676594,1.034513784,1.960058896,0.073431462,DB0111810002034_,2.611402799,0.353944837,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,amiodarone,DB01118
,13970,DB08908,10002034,52,10621,6,3273,0.018720343,2.670700116,1.146079362,7.614426942,0.058655885,DB0890810002034_,2.836067372,0.982340654,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,dimethyl fumarate,DB08908
,13971,DB00115,10017955,113,18312,96,10376,0.003843666,0.667001687,0.503030777,0.885839987,0.016517741,DB0011510017955_,4.103320247,-0.404962704,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,13972,DB00193,10017955,125,19195,104,8598,5.30354246141965e-06,0.538361415,0.41119521,0.706125428,6.22615514061704e-05,DB0019310017955_,9.684166475,-0.619225169,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,13974,DB00381,10017955,220,29140,254,22633,1.8086190371901e-05,0.672746171,0.558571657,0.809756337,0.000182669,DB0038110017955_,8.607835961,-0.39638718,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,13976,DB00706,10017955,9,1066,174,15751,0.54084413,0.764264333,0.34273764,1.49040119,0.696320923,DB0070610017955_,0.361944629,-0.268841564,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,tamsulosin,DB00706
,13977,DB00727,10017955,83,3760,133,4040,0.004609114,0.670568385,0.501628268,0.892119015,0.019149698,DB0072710017955_,3.955468348,-0.39962959,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,nitroglycerin,DB00727
,13978,DB00736,10017955,84,10507,73,5480,0.001723321,0.600146395,0.432591281,0.834331527,0.008600246,DB0073610017955_,4.755964477,-0.510581661,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,13979,DB00996,10017955,170,38783,153,22272,7.65250868639293e-05,0.638114718,0.509514302,0.799632397,0.000633831,DB0099610017955_,7.363728584,-0.449237203,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,13980,DB01076,10017955,258,25489,345,25238,0.00030531,0.740469134,0.627080262,0.873482517,0.002047475,DB0107610017955_,6.191147792,-0.300471328,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,13981,DB01118,10017955,129,2934,157,4552,0.048429507,1.274713434,0.997132132,1.627253189,0.122136684,DB0111810017955_,2.1026145,0.242721395,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,amiodarone,DB01118
,13985,DB00005,10047942,291,127791,84,42335,0.282073862,1.14765632,0.897144328,1.481368381,0.446073662,DB0000510047942_,0.807271179,0.13772188,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,etanercept,DB00005
,13987,DB00046,10016256,229,5230,173,4519,0.202002533,1.14373163,0.930780825,1.407363896,0.351398847,DB0004610016256_,1.045833384,0.134296276,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,13989,DB00047,10022052,61,9224,29,8489,0.002951143,1.935761761,1.223539992,3.127784097,0.013320303,DB0004710022052_,4.318465885,0.660500924,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,13990,DB00153,10022052,77,7346,12,3427,0.00012693,2.99321771,1.616214993,6.05073592,0.000978181,DB0015310022052_,6.929815673,1.096348966,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,13991,DB00331,10022052,100,24846,30,20722,1.94497677430184e-07,2.779908712,1.831716292,4.333942481,3.30897828560026e-06,DB0033110022052_,12.61887109,1.02241809,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,13993,DB00047,10048865,15,9270,42,8476,8.98634130713765e-05,0.326571694,0.168097675,0.601591115,0.000728918,DB0004710048865_,7.223948878,-1.119105772,male,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,insulin glargine,DB00047
,13995,DB00331,10048865,55,24891,51,20701,0.625617858,0.896897667,0.60120735,1.340170319,0.76522501,DB0033110048865_,0.267585358,-0.108813507,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,metformin,DB00331
,13996,DB00563,10017577,459,46187,125,15223,0.060316557,1.210263352,0.990159125,1.488205892,0.144046394,DB0056310017577_,1.937619852,0.190837982,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,13997,DB01050,10017577,253,17855,93,9278,0.004267717,1.413601167,1.108752823,1.815343807,0.018007376,DB0105010017577_,4.016973822,0.346140468,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,13998,DB00563,10052904,834,45812,229,15119,0.014746606,1.201907807,1.035951477,1.398927069,0.048655563,DB0056310052904_,3.022989129,0.183910133,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,14000,DB00051,10048959,427,25304,147,11273,0.007114701,1.294029743,1.06897795,1.573786321,0.027138284,DB0005110048959_,3.606809843,0.257761181,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,14001,DB00051,10068319,132,25599,49,11371,0.295145664,1.196593131,0.855285162,1.698052449,0.461066432,DB0005110068319_,0.774213143,0.179478462,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,14002,DB00051,10000496,77,25654,42,11378,0.275459947,0.813143558,0.550885189,1.214923592,0.438766325,DB0005110000496_,0.823788298,-0.206847607,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,14003,DB00051,10000081,359,25372,202,11218,0.007443908,0.785760276,0.658534402,0.939674193,0.028126663,DB0005110000081_,3.571037274,-0.241103525,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,14004,DB00115,10000081,303,18122,115,10357,0.000175779,1.505798028,1.209243622,1.885684067,0.001293853,DB0011510000081_,6.650131063,0.409323009,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,14005,DB00213,10000081,405,18490,221,13200,0.001388123,1.308265664,1.105947145,1.550712566,0.00721156,DB0021310000081_,4.932070003,0.26870234,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,14006,DB00497,10000081,351,18916,240,16135,0.008732586,1.247476567,1.054085289,1.478281778,0.031953229,DB0049710000081_,3.443482049,0.221122765,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,14007,DB00635,10000081,549,32504,360,23434,0.175207009,1.099484077,0.959792136,1.260637204,0.317728535,DB0063510000081_,1.146557926,0.094841049,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,14008,DB01373,10000081,245,22475,59,7322,0.037719991,1.352801799,1.013045444,1.831802625,0.101051823,DB0137310000081_,2.29212179,0.302177848,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,14009,DB00051,10022067,114,25617,50,11370,1,1.011972463,0.719099038,1.441917333,1,DB0005110022067_,0,0.01190136,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,14011,DB00169,10022067,65,38626,22,18153,0.206058788,1.388568019,0.844455833,2.366105527,0.356520224,DB0016910022067_,1.031364312,0.328273014,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,14015,DB00635,10022067,97,32956,41,23753,0.00419455,1.705165883,1.171629918,2.521314382,0.01775305,DB0063510022067_,4.031197965,0.533662398,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,14016,DB01373,10022067,47,22673,9,7372,0.16266492,1.697887423,0.8221053,3.942750137,0.300942983,DB0137310022067_,1.200834456,0.529384786,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,14018,DB00186,10022086,87,16814,19,9989,1.89878891703299e-05,2.720199384,1.640759657,4.736657931,0.000190932,DB0018610022086_,8.563592375,1.000705181,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,14019,DB00213,10022086,121,18774,48,13373,0.000535271,1.795589725,1.27428978,2.565703824,0.003264032,DB0021310022086_,5.724792007,0.585333506,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,14020,DB00497,10022086,80,19187,31,16344,0.000119415,2.198160137,1.434541794,3.445603445,0.000927812,DB0049710022086_,6.982680923,0.787620709,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,14021,DB01592,10022086,70,6206,13,3054,0.000577353,2.649564932,1.450507039,5.229591738,0.003479875,DB0159210022086_,5.660758808,0.97439545,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,14022,DB00051,10047895,251,25480,189,11231,5.5539460548548e-08,0.585379197,0.482097334,0.711764868,1.06403405285611e-06,DB0005110047895_,13.75344316,-0.535495442,NA,10047895,Weight decreased,10022891,Investigations,Inv,adalimumab,DB00051
,14023,DB00186,10047895,334,16567,207,9801,0.62117096,0.954575796,0.798735141,1.142943213,0.761528748,DB0018610047895_,0.272427355,-0.046488229,NA,10047895,Weight decreased,10022891,Investigations,Inv,lorazepam,DB00186
,14024,DB00213,10047895,379,18516,288,13133,0.382755262,0.93339317,0.797333635,1.093548295,0.552862869,DB0021310047895_,0.592645285,-0.068928763,NA,10047895,Weight decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,14025,DB00497,10047895,384,18883,301,16074,0.29610386,1.085999113,0.930016491,1.268979767,0.46195928,DB0049710047895_,0.77227853,0.082500405,NA,10047895,Weight decreased,10022891,Investigations,Inv,oxycodone,DB00497
,14026,DB01373,10047895,431,22289,184,7197,0.002061285,0.756353367,0.633628396,0.90566927,0.009968884,DB0137310047895_,4.608286614,-0.279246596,NA,10047895,Weight decreased,10022891,Investigations,Inv,calcium,DB01373
,14027,DB01592,10047895,178,6098,98,2969,0.330024504,0.884352166,0.68445552,1.148102158,0.498658501,DB0159210047895_,0.695833785,-0.122899918,NA,10047895,Weight decreased,10022891,Investigations,Inv,iron,DB01592
,14063,DB01012,10061105,43,10589,34,8651,0.909158413,1.033242219,0.64305308,1.672293802,0.959169515,DB0101210061105_,0.041687457,0.032701644,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,cinacalcet,DB01012
,14076,DB00005,10012374,179,127903,49,42370,0.250892292,1.21013089,0.877643278,1.696066007,0.410744224,DB0000510012374_,0.889784584,0.190728527,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,14079,DB00338,10019860,38,33636,15,22257,0.09316332,1.676293903,0.900578649,3.281151006,0.200368028,DB0033810019860_,1.607599462,0.516585346,NA,10019860,Hereditary angioedema,10010331,"Congenital, familial and genetic disorders",Cong,omeprazole,DB00338
,14081,DB00668,10019860,210,9881,50,4253,9.26931380438561e-05,1.80770705,1.319304028,2.518292659,0.000747603,DB0066810019860_,7.198638077,0.592059219,NA,10019860,Hereditary angioedema,10010331,"Congenital, familial and genetic disorders",Cong,epinephrine,DB00668
,14083,DB01109,10019860,91,4321,19,4251,3.26030150320293e-12,4.710952116,2.844906488,8.197025712,1.34637902610666e-10,DB0110910019860_,22.72843214,1.549890035,female,10019860,Hereditary angioedema,10010331,"Congenital, familial and genetic disorders",Cong,heparin,DB01109
,14092,DB08932,10042609,105,19338,37,6560,0.846711141,0.962674485,0.655311184,1.442441839,0.922998542,DB0893210042609_,0.080127624,-0.038039946,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,14094,DB08908,10061822,256,10417,42,3237,5.72384382052346e-05,1.893874163,1.358890088,2.698001739,0.000495313,DB0890810061822_,7.610321263,0.638624553,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,14095,DB08908,10073085,167,10506,35,3244,0.036647358,1.473236303,1.015978348,2.190979991,0.09887865,DB0890810073085_,2.31386194,0.387461547,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,dimethyl fumarate,DB08908
,14096,DB00682,10022594,135,19324,155,16209,0.009097868,0.730581333,0.575107658,0.927126722,0.033014075,DB0068210022594_,3.410821305,-0.313914715,NA,10022594,International normalised ratio decreased,10022891,Investigations,Inv,warfarin,DB00682
,14099,DB01015,10013687,24,9863,32,9349,0.229071951,0.710930921,0.400387846,1.246541151,0.384799887,DB0101510013687_,0.955031854,-0.341180011,NA,10013687,Drug eruption,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,14101,DB01068,10021789,121,13642,34,6806,0.002618503,1.775453909,1.203414149,2.682993756,0.012097259,DB0106810021789_,4.414776355,0.574056114,NA,10021789,Infection,10021881,Infections and infestations,Infec,clonazepam,DB01068
,14103,DB01202,10021789,44,6670,35,5683,0.821199043,1.071131992,0.670506726,1.722737301,0.904725148,DB0120210021789_,0.100124085,0.068716025,NA,10021789,Infection,10021881,Infections and infestations,Infec,levetiracetam,DB01202
,14104,DB00706,10003549,45,1030,628,15297,0.68592818,1.064217123,0.763236492,1.451916103,0.810411157,DB0070610003549_,0.210213559,0.062239433,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,14105,DB01132,10003549,41,1244,47,1483,0.913534002,1.03993967,0.662225282,1.627369305,0.961302297,DB0113210003549_,0.039466354,0.039162701,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pioglitazone,DB01132
,14106,DB01275,10003549,111,3868,119,3230,0.069234222,0.778949828,0.593327583,1.022008888,0.159949155,DB0127510003549_,1.832899293,-0.249808641,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,14107,DB06643,10003549,554,51867,140,7375,1.2412146988696e-08,0.562676058,0.465843488,0.683348579,2.73702419125733e-07,DB0664310003549_,15.11122438,-0.575051202,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,14108,DB00158,10003988,330,16485,114,7990,0.001791506,1.403015121,1.128588572,1.754622221,0.008887133,DB0015810003988_,4.723150771,0.338623578,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,14109,DB00177,10003988,92,4708,49,2801,0.598023606,1.11704269,0.778800769,1.619076045,0.742999711,DB0017710003988_,0.297059623,0.110684738,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,valsartan,DB00177
,14110,DB00222,10003988,64,3142,49,3079,0.217329327,1.279880731,0.865386977,1.903016658,0.370268432,DB0022210003988_,0.993527044,0.246766895,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,glimepiride,DB00222
,14111,DB00381,10003988,593,28767,333,22554,1.02776843919706e-06,1.396162922,1.217307612,1.603399838,1.46431995091599e-05,DB0038110003988_,11.13153453,0.333727704,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,14112,DB00451,10003988,1007,46264,246,15173,2.90911236322233e-05,1.342500212,1.165235638,1.551543268,0.0002761,DB0045110003988_,8.194745824,0.294533705,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,14113,DB00706,10003988,31,1044,288,15637,0.019264336,1.612144407,1.069592597,2.353870978,0.060038307,DB0070610003988_,2.812772476,0.477565222,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tamsulosin,DB00706
,14115,DB01275,10003988,39,3940,32,3317,1,1.026038662,0.624819898,1.696042867,1,DB0127510003988_,0,0.025705428,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydralazine,DB01275
,14116,DB00158,10008469,84,16731,37,8067,0.697818861,1.094624473,0.734471768,1.659652905,0.818262715,DB0015810008469_,0.200571827,0.090411357,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,14119,DB00381,10008469,189,29171,109,22778,0.011781521,1.353931198,1.06325997,1.731073172,0.040579373,DB0038110008469_,3.2044954,0.303012359,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,14123,DB06643,10008469,63,52358,10,7505,0.723682891,0.903072037,0.459856641,1.975000181,0.837567909,DB0664310008469_,0.177252933,-0.101952953,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,14124,DB00158,10008479,207,16608,98,8006,0.902298524,1.018233026,0.795629767,1.310455967,0.957195726,DB0015810008479_,0.043747388,0.018068798,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,14125,DB00177,10008479,63,4737,41,2809,0.683201369,0.911194616,0.603473657,1.38915185,0.808457376,DB0017710008479_,0.212627322,-0.092998776,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,14126,DB00222,10008479,45,3161,33,3095,0.212578941,1.33509965,0.830698562,2.165960974,0.364526044,DB0022210008479_,1.009157278,0.289005934,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,14127,DB00706,10008479,16,1059,188,15737,0.382701411,1.264680954,0.705560161,2.118157597,0.552820149,DB0070610008479_,0.592722559,0.23481988,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,14129,DB01275,10008479,86,3893,63,3286,0.407410755,1.152212397,0.819910944,1.626655668,0.576908316,DB0127510008479_,0.550071923,0.141683918,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,14130,DB00158,10013700,247,16568,41,8063,1.54797665262772e-12,2.931732161,2.097508169,4.191307536,6.73651760170856e-11,DB0015810013700_,23.42089291,1.075593429,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,folic acid,DB00158
,14131,DB00177,10013700,125,4675,33,2817,9.00991738277477e-06,2.282228582,1.53952784,3.468805748,9.91940014266952e-05,DB0017710013700_,9.218433015,0.825152414,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,valsartan,DB00177
,14132,DB00222,10013700,68,3138,39,3089,0.008203758,1.71621003,1.137215588,2.622070875,0.030407638,DB0022210013700_,3.493061442,0.540118388,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,glimepiride,DB00222
,14133,DB00706,10013700,20,1055,128,15797,0.001718819,2.339434588,1.376866163,3.78420617,0.008583482,DB0070610013700_,4.757915664,0.849909271,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,tamsulosin,DB00706
,14134,DB01275,10013700,86,3893,48,3301,0.022650253,1.519123384,1.051577538,2.216975961,0.068084155,DB0127510013700_,2.68701077,0.418133447,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,hydralazine,DB01275
,14135,DB00158,10013968,610,16205,281,7823,0.536044947,1.047967806,0.905948927,1.214522899,0.692448468,DB0015810013968_,0.367521458,0.046852866,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,14136,DB00222,10013968,153,3053,115,3013,0.033653771,1.312943103,1.018488076,1.696293525,0.09269616,DB0022210013968_,2.378428233,0.272271261,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glimepiride,DB00222
,14137,DB00706,10013968,33,1042,650,15275,0.10837031,0.744283589,0.505092718,1.06285511,0.223575541,DB0070610013968_,1.498005932,-0.295333149,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tamsulosin,DB00706
,14138,DB01132,10013968,55,1230,58,1472,0.563243868,1.134794548,0.763921132,1.684044728,0.715297262,DB0113210013968_,0.335057072,0.126451619,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pioglitazone,DB01132
,14139,DB01275,10013968,255,3724,168,3181,0.011873745,1.296489222,1.056556551,1.594206506,0.040832126,DB0127510013968_,3.19828611,0.259660012,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydralazine,DB01275
,14140,DB00177,10016256,311,4489,162,2688,0.169392595,1.149558298,0.94173401,1.407204501,0.310093976,DB0017710016256_,1.170879878,0.13937778,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,14141,DB00222,10016256,191,3015,176,2952,0.590884545,1.062568201,0.855657706,1.320061618,0.737392162,DB0022210016256_,0.304635423,0.060688809,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,14142,DB00706,10016256,72,1003,1114,14811,0.757230606,0.95440027,0.735004176,1.223401754,0.864255601,DB0070610016256_,0.14588672,-0.046672125,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,14143,DB01132,10016256,53,1232,77,1453,0.279565218,0.811843567,0.556307971,1.177265212,0.443392025,DB0113210016256_,0.813300968,-0.208447609,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pioglitazone,DB01132
,14144,DB01275,10016256,211,3768,169,3180,0.634448433,1.053694663,0.851698846,1.30507532,0.772713667,DB0127510016256_,0.257846716,0.052302715,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,14145,DB06643,10016256,1028,51393,302,7213,3.98061999641605e-25,0.477752137,0.418784967,0.54626848,6.11874833952023e-23,DB0664310016256_,51.14809958,-0.738663224,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,14146,DB00158,10025482,556,16259,150,7954,2.40502099685029e-11,1.813284099,1.508273936,2.190836614,8.64196540016539e-10,DB0015810025482_,20.8692209,0.59513962,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,14147,DB00177,10025482,216,4584,69,2781,2.45764532029283e-06,1.89900858,1.435507703,2.538306945,3.17051323896427e-05,DB0017710025482_,10.35903199,0.64133195,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,14148,DB00222,10025482,106,3100,62,3066,0.001279472,1.690777835,1.219233801,2.361563974,0.006738313,DB0022210025482_,4.999945628,0.52518868,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,14149,DB00381,10025482,990,28370,416,22471,1.50473112364092e-28,1.884928474,1.677046099,2.121632026,3.04245058345396e-26,DB0038110025482_,58.75454911,0.633889875,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,14150,DB00706,10025482,21,1054,319,15606,1,0.974720565,0.592403202,1.523913048,1,DB0070610025482_,0,-0.02560445,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,14152,DB01275,10025482,110,3869,65,3284,0.021340493,1.436354692,1.043617418,1.990347647,0.065100081,DB0127510025482_,2.731829487,0.36210844,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,14153,DB00158,10028391,139,16676,59,8045,0.446612974,1.136559115,0.831350786,1.570475199,0.614378321,DB0015810028391_,0.487144382,0.128005378,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,14156,DB00381,10028391,176,29184,69,22818,5.47451409081872e-07,1.994279974,1.500657328,2.675791009,8.41501125997478e-06,DB0038110028391_,11.68549339,0.69028307,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,14157,DB00451,10028391,292,46979,75,15344,0.068035532,1.271602972,0.98285982,1.66269,0.157762247,DB0045110028391_,1.846666148,0.240278288,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,14161,DB06643,10028391,543,51878,37,7478,1.44694040620804e-06,2.115414078,1.51379389,3.039850951,1.99542647309436e-05,DB0664310028391_,10.82206767,0.749250575,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,14162,DB00158,10028836,97,16718,26,8078,0.006682316,1.802638722,1.158178574,2.898809421,0.025820349,DB0015810028836_,3.656592372,0.589251548,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,14165,DB00381,10028836,158,29202,65,22822,7.20803346516064e-06,1.899659804,1.413743735,2.57788076,8.14720101620071e-05,DB0038110028836_,9.41525103,0.64167482,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,14166,DB00451,10028836,302,46969,63,15356,0.000961474,1.567174669,1.190387541,2.091542958,0.00533453,DB0045110028836_,5.233554459,0.449274424,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,14170,DB06643,10028836,210,52211,18,7497,0.034753126,1.675208055,1.033560364,2.883700074,0.094960992,DB0664310028836_,2.354289084,0.51593737,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,14171,DB00158,10018836,41,16774,23,8081,0.593483972,0.858800127,0.502976668,1.500328243,0.739516282,DB0015810018836_,0.30175898,-0.152219065,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,14174,DB00338,10018836,100,33574,76,22196,0.356142348,0.869882609,0.638755615,1.188704031,0.525838337,DB0033810018836_,0.642761458,-0.139397008,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,14177,DB00563,10018836,39,46607,30,15318,0.000680401,0.427265914,0.258574502,0.712487576,0.003997843,DB0056310018836_,5.522000226,-0.85034871,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,14178,DB00635,10018836,93,32960,75,23719,0.481353867,0.89234423,0.650892555,1.226815505,0.646024325,DB0063510018836_,0.436918121,-0.113903312,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,14185,DB00338,10031252,40,33634,36,22236,0.19726217,0.734591849,0.456298205,1.186441427,0.345688097,DB0033810031252_,1.062218364,-0.308440241,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,omeprazole,DB00338
,14188,DB00563,10031252,52,46594,47,15301,9.98074331278256e-07,0.363332152,0.240039141,0.551241223,1.42811016862542e-05,DB0056310031252_,11.15657346,-1.012437844,male,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,methotrexate,DB00563
,14189,DB00635,10031252,73,32980,55,23739,0.788812689,0.955341693,0.663776403,1.381948083,0.885573892,DB0063510031252_,0.121519379,-0.045686208,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,prednisone,DB00635
,14191,DB00996,10031252,61,38892,57,22368,0.009559592,0.615526002,0.421710076,0.899538737,0.034352843,DB0099610031252_,3.371070493,-0.485278089,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,gabapentin,DB00996
,14194,DB00158,10061818,92,16723,72,8032,0.002499038,0.613714557,0.445399773,0.848450674,0.011654934,DB0015810061818_,4.45202569,-0.488225349,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,14195,DB00196,10061818,52,5031,54,3231,0.015969805,0.618489927,0.413239665,0.924922593,0.051759104,DB0019610061818_,2.96115494,-0.480474373,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,14197,DB00482,10061818,36,8223,27,3044,0.006666318,0.493591429,0.290881934,0.846921676,0.025773945,DB0048210061818_,3.658391172,-0.70604717,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,14198,DB00512,10061818,33,4704,40,5058,0.639660764,0.887096574,0.541075243,1.445398356,0.776711932,DB0051210061818_,0.252685741,-0.119801426,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,14199,DB00563,10061818,110,46536,68,15280,7.85579154791976e-05,0.531180826,0.388821109,0.730082105,0.000648726,DB0056310061818_,7.340500142,-0.632652777,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,14201,DB01137,10061818,71,7701,61,5532,0.32968023,0.836125601,0.584333706,1.199484842,0.498354939,DB0113710061818_,0.696442728,-0.178976437,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,14206,DB01048,10037844,14,451,39,1096,0.759300577,0.872440411,0.433131345,1.661718553,0.86586619,DB0104810037844_,0.144024898,-0.136460924,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,abacavir,DB01048
,14211,DB01609,10011906,99,1485,144,1199,1.53733304283824e-05,0.55521477,0.420526768,0.730703617,0.000158342,DB0160910011906_,8.750755271,-0.588400267,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,deferasirox,DB01609
,14215,DB00811,10047895,86,2712,97,4059,0.066523364,1.326878711,0.976709152,1.800137412,0.155089207,DB0081110047895_,1.863754802,0.28282935,NA,10047895,Weight decreased,10022891,Investigations,Inv,ribavirin,DB00811
,14216,DB08934,10047895,39,4450,68,6136,0.278952249,0.790843592,0.518303205,1.191856987,0.442812459,DB0893410047895_,0.814608941,-0.234655065,NA,10047895,Weight decreased,10022891,Investigations,Inv,sofosbuvir,DB08934
,14218,DB00811,10061428,88,2710,108,4048,0.183907312,1.217066701,0.903891594,1.635110554,0.32882142,DB0081110061428_,1.112240471,0.19644362,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ribavirin,DB00811
,14219,DB08934,10061428,77,4412,108,6096,0.940242551,0.985091812,0.723704672,1.335512574,0.979559074,DB0893410061428_,0.020652733,-0.015020432,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,sofosbuvir,DB08934
,14220,DB01115,10012174,55,3545,25,2243,0.203356963,1.391913225,0.849992025,2.338276843,0.353077335,DB0111510012174_,1.041068168,0.330679222,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,nifedipine,DB01115
,14223,DB01115,10025482,146,3454,33,2235,4.6912004271184e-09,2.862349857,1.942462,4.329727894,1.13439009408286e-07,DB0111510025482_,15.99200051,1.051642916,female,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,14225,DB06404,10028813,54,3015,19,881,0.481922114,0.830504938,0.481412974,1.491990333,0.646365533,DB0640410028813_,0.436390095,-0.185721404,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,human c1-esterase inhibitor,DB06404
,14226,DB01115,10053762,107,3493,53,2215,0.161718173,1.280156425,0.908472462,1.822732623,0.299697689,DB0111510053762_,1.204981017,0.246982278,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,nifedipine,DB01115
,14231,DB00704,10012378,162,4194,202,4992,0.707303164,0.954569123,0.768255119,1.184641898,0.82502224,DB0070410012378_,0.192344936,-0.04649522,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,14232,DB00193,10016173,639,18681,256,8446,0.11436814,1.128516184,0.97237933,1.312727275,0.232684436,DB0019310016173_,1.458072097,0.120903658,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,14233,DB01234,10016173,736,30889,653,32235,0.002836387,1.176215186,1.055886309,1.310462038,0.012913211,DB0123410016173_,4.349504411,0.162301814,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,14234,DB00193,10060820,40,19280,14,8688,0.464488847,1.287445201,0.685313634,2.563500899,0.631531842,DB0019310060820_,0.459606915,0.252659791,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,14235,DB00316,10060820,117,65357,39,36914,0.003451826,1.694407797,1.169881501,2.501910285,0.015149649,DB0031610060820_,4.189777915,0.527333298,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,14237,DB00480,10060820,72,67356,43,67619,0.00672232,1.680939722,1.136306128,2.513029149,0.025938737,DB0048010060820_,3.652017784,0.519352995,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,14241,DB01240,10025482,558,5193,108,1468,0.000365596,1.460433973,1.176301564,1.826525735,0.002378636,DB0124010025482_,6.041228212,0.378733634,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,14242,DB08932,10025482,1532,17911,372,6225,6.88667649134034e-10,1.431350685,1.272338233,1.613216148,1.97185502804881e-08,DB0893210025482_,17.74170601,0.358618533,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,14243,DB01240,10030095,284,5467,78,1498,1,0.997669302,0.768564177,1.307404308,1,DB0124010030095_,0,-0.002333418,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,14244,DB08932,10030095,758,18685,288,6309,0.095231493,0.888692949,0.772500285,1.024485807,0.203566853,DB0893210030095_,1.591760814,-0.118003492,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,14247,DB00921,10053762,134,5711,134,4769,0.153261878,0.835071659,0.650200843,1.072501947,0.288553003,DB0092110053762_,1.242876492,-0.180237739,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,buprenorphine,DB00921
,14248,DB00682,10060321,47,19412,116,16248,6.78115735653941e-11,0.33914233,0.236162779,0.480175789,2.28077698165884e-09,DB0068210060321_,19.89874967,-1.081335406,male,10060321,Anticoagulation drug level below therapeutic,10022891,Investigations,Inv,warfarin,DB00682
,14249,DB00682,10069327,59,19400,51,16313,0.923752874,0.972770975,0.656956401,1.444782444,0.966829343,DB0068210069327_,0.03373328,-0.027606605,NA,10069327,Product quality issue,10077536,Product issues,Prod,warfarin,DB00682
,14250,DB00175,10007559,91,8040,96,6010,0.020984413,0.708607031,0.524950688,0.955911853,0.064207016,DB0017510007559_,2.745642785,-0.344454164,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,pravastatin,DB00175
,14251,DB00178,10007559,23,1414,31,1649,0.680142387,0.865281884,0.479393978,1.540854888,0.806529939,DB0017810007559_,0.215014259,-0.144699948,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,ramipril,DB00178
,14252,DB00316,10007559,391,65083,292,36661,0.000316137,0.754298996,0.646166753,0.881277,0.002106379,DB0031610007559_,6.162784874,-0.281966443,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,14254,DB00175,10011078,24,8107,37,6069,0.006131144,0.485605462,0.277613247,0.834667416,0.024078457,DB0017510011078_,3.726437745,-0.722358792,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,pravastatin,DB00175
,14257,DB00264,10011078,90,29517,146,24746,7.3372386125371e-07,0.516812521,0.392696763,0.677033278,1.08867805210577e-05,DB0026410011078_,11.4279613,-0.660075098,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,metoprolol,DB00264
,14258,DB00316,10011078,81,65393,89,36864,1.90877686092328e-05,0.513046775,0.374854475,0.701361818,0.00019168,DB0031610011078_,8.559684044,-0.667388258,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,14259,DB00437,10011078,14,6907,38,11508,0.15057513,0.613854986,0.306990807,1.160016438,0.284748897,DB0043710011078_,1.256147549,-0.487996557,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,allopurinol,DB00437
,14260,DB00695,10011078,68,27981,119,20409,4.42996618119464e-09,0.416798087,0.304561575,0.56645693,1.07666815601203e-07,DB0069510011078_,16.04422442,-0.875153377,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,furosemide,DB00695
,14261,DB00761,10011078,36,15271,35,8590,0.025225139,0.578559159,0.352821398,0.949694967,0.07399618,DB0076110011078_,2.603741812,-0.547214475,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,14263,DB00175,10028596,53,8078,84,6022,1.74475775716238e-05,0.470383569,0.326479144,0.672466727,0.000177001,DB0017510028596_,8.639355207,-0.754206812,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,pravastatin,DB00175
,14264,DB00178,10028596,13,1424,44,1636,0.000392884,0.339567995,0.167068138,0.645004406,0.002525547,DB0017810028596_,5.981297701,-1.080081071,male,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,ramipril,DB00178
,14265,DB00186,10028596,65,16836,69,9939,0.00085049,0.55615706,0.389763221,0.792763996,0.00481584,DB0018610028596_,5.335844749,-0.586704543,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,lorazepam,DB00186
,14266,DB00437,10028596,44,6877,117,11429,0.00695034,0.625009497,0.430941223,0.892298489,0.026652519,DB0043710028596_,3.6248716,-0.469988434,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,allopurinol,DB00437
,14267,DB00695,10028596,233,27816,294,20234,4.26172361587117e-10,0.57651488,0.482874079,0.687663018,1.26361427234263e-08,DB0069510028596_,18.18670466,-0.550754128,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,furosemide,DB00695
,14268,DB00788,10028596,35,9321,41,5020,0.000992596,0.459772787,0.283907012,0.741011311,0.005467964,DB0078810028596_,5.208848864,-0.777022852,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,naproxen,DB00788
,14269,DB00005,10029174,113,127969,62,42357,0.002076672,0.603265986,0.438648605,0.836329241,0.010032611,DB0000510029174_,4.601914412,-0.505397075,NA,10029174,Nerve compression,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,14271,DB00005,10062262,266,127816,121,42298,0.004645542,0.727498106,0.584472401,0.909860248,0.019269903,DB0000510062262_,3.949210835,-0.318143884,NA,10062262,Spinal operation,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,14276,DB08895,10022004,175,27939,34,6612,0.331805825,1.218086799,0.838873768,1.816491983,0.50061807,DB0889510022004_,0.691911803,0.197281431,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,14277,DB08895,10033371,1953,26161,394,6252,0.002782085,1.184588835,1.058664274,1.32800428,0.012712231,DB0889510033371_,4.365190712,0.169395739,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,14278,DB08895,10048334,126,27988,28,6618,0.837588087,1.064088446,0.701357003,1.666671997,0.916340751,DB0889510048334_,0.087366985,0.062118513,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,14279,DB08895,10056819,142,27972,17,6629,0.006042623,1.979479002,1.192509551,3.495846381,0.023796915,DB0889510056819_,3.738199309,0.68283368,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,14280,DB00982,10042458,109,3255,142,1959,3.43978525730722e-09,0.462040396,0.354318088,0.601206193,8.57348198380208e-08,DB0098210042458_,16.27200679,-0.772102955,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,isotretinoin,DB00982
,14283,DB00331,10014625,60,24886,57,20695,0.515448318,0.875363834,0.598631746,1.281277191,0.675216617,DB0033110014625_,0.392721725,-0.133115668,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,metformin,DB00331
,14284,DB00437,10014625,41,6880,53,11493,0.240022991,1.292226642,0.8371393,1.982191555,0.397868721,DB0043710014625_,0.921633174,0.256366809,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,14286,DB00641,10014625,58,14066,21,12454,0.000262376,2.4452033,1.460828533,4.244509784,0.001807511,DB0064110014625_,6.315804267,0.894128269,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,14287,DB00695,10014625,95,27954,73,20455,0.754951111,0.95229087,0.694115499,1.310966884,0.862429787,DB0069510014625_,0.14800154,-0.048884755,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,14289,DB01202,10014625,65,6649,80,5638,0.029098319,0.688984473,0.487887738,0.969889969,0.082717711,DB0120210014625_,2.492321537,-0.372536544,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,14290,DB01413,10014625,55,1165,61,1598,0.29152386,1.236654244,0.836124068,1.82555814,0.456970191,DB0141310014625_,0.783137117,0.212409543,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,cefepime,DB01413
,14291,DB00186,10041962,36,16865,38,9970,0.015438649,0.560088951,0.344737609,0.90831299,0.050426207,DB0018610041962_,2.987244266,-0.579659668,NA,10041962,Status epilepticus,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,14299,DB01202,10041962,100,6614,90,5628,0.714288594,0.945443139,0.702361853,1.274263308,0.830608551,DB0120210041962_,0.185596652,-0.056101531,NA,10041962,Status epilepticus,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,14321,DB01164,10067442,65,6459,62,7874,0.179471751,1.278032494,0.886993371,1.843060085,0.323225358,DB0116410067442_,1.129405497,0.245321782,NA,10067442,Bloody peritoneal effluent,10017947,Gastrointestinal disorders,Gastr,calcium chloride,DB01164
,14322,DB00559,10055798,87,9572,27,3279,0.746218994,1.103800511,0.708121778,1.77208316,0.85529003,DB0055910055798_,0.156314651,0.098759235,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,bosentan,DB00559
,14327,DB00016,10013573,72,2690,42,2248,0.070701757,1.432504814,0.961484094,2.158040046,0.162521975,DB0001610013573_,1.816942054,0.35942453,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,erythropoietin,DB00016
,14328,DB09053,10013573,59,2226,85,3967,0.219782657,1.236939435,0.868289032,1.752291006,0.373178331,DB0905310013573_,0.985698875,0.212640131,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ibrutinib,DB09053
,14331,DB09053,10037660,84,2201,130,3922,0.34648459,1.151359798,0.860019429,1.534622726,0.515923945,DB0905310037660_,0.661795917,0.140943677,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ibrutinib,DB09053
,14332,DB00073,10013709,663,6743,298,6109,1.08259667502333e-23,2.015537588,1.747484491,2.328738475,1.5340190621557e-21,DB0007310013709_,47.92639582,0.700885953,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,14335,DB00073,10040753,66,7340,38,6369,0.048162432,1.507029371,0.99467951,2.312678389,0.121638195,DB0007310040753_,2.106704257,0.410140409,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,rituximab,DB00073
,14336,DB00073,10047571,38,7368,19,6388,0.061522452,1.733912869,0.973970103,3.187665857,0.146259455,DB0007310047571_,1.922373146,0.550380629,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,rituximab,DB00073
,14337,DB00005,10072005,152,127930,55,42364,0.573660074,0.915168651,0.668020873,1.269875838,0.723493303,DB0000510072005_,0.32366399,-0.088646913,NA,10072005,Spinal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,14339,DB00682,10017788,36,19423,467,15897,3.53586508027578e-115,0.063067057,0.043624506,0.088701863,8.44911033045899e-112,DB0068210017788_,255.7554693,-2.763556726,male,10017788,Gastric haemorrhage,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,14340,DB00537,10055798,31,7526,24,4274,0.262753362,0.733577217,0.416072582,1.308050887,0.42451731,DB0053710055798_,0.856802496,-0.309822415,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,ciprofloxacin,DB00537
,14341,DB00682,10055798,283,19176,707,15657,9.01503272050518e-62,0.326836494,0.283271308,0.376312786,8.03254695113487e-59,DB0068210055798_,133.7690188,-1.118295253,male,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,warfarin,DB00682
,14344,DB00230,10015090,52,19622,13,8638,0.078695315,1.760849439,0.944853752,3.527013347,0.176133034,DB0023010015090_,1.736515696,0.565796328,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,14346,DB00316,10037087,1331,64143,483,36470,5.75893211036666e-18,1.566806777,1.409698862,1.743816644,4.95494371590795e-16,DB0031610037087_,35.24097568,0.449039648,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,14347,DB00588,10037087,406,16118,117,8351,7.80605668317623e-09,1.79786928,1.457564865,2.231645194,1.79590546973556e-07,DB0058810037087_,15.53258632,0.58660223,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,14348,DB00635,10037087,670,32383,242,23552,3.38058219998463e-22,2.013546779,1.734013648,2.344427038,4.35581387875471e-20,DB0063510037087_,44.58019038,0.699897734,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,14349,DB00668,10037087,212,9879,50,4253,7.27797587686329e-05,1.825291833,1.332582413,2.542030536,0.000606729,DB0066810037087_,7.407428627,0.601739883,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,epinephrine,DB00668
,14350,DB00678,10037087,358,15241,176,10548,0.000215842,1.407735941,1.169967555,1.6987525,0.00153632,DB0067810037087_,6.478365551,0.341982698,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,14351,DB01075,10037087,767,19181,342,10755,0.000500926,1.257455527,1.10307985,1.435784607,0.003095532,DB0107510037087_,5.777795651,0.229090256,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,14352,DB01098,10037087,195,7954,110,7099,0.000124479,1.582119301,1.243185554,2.021812871,0.00096191,DB0109810037087_,6.946589779,0.458765278,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,rosuvastatin,DB01098
,14353,DB01109,10037087,70,4342,29,4241,6.71386870147192e-05,2.357578386,1.505494569,3.778579404,0.000566894,DB0110910037087_,7.47533858,0.857634985,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,heparin,DB01109
,14355,DB09153,10037087,117,7682,53,5646,0.003714524,1.622409761,1.160873107,2.293300211,0.016066522,DB0915310037087_,4.131017545,0.483912551,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,sodium chloride,DB09153
,14356,DB00316,10037844,1562,63912,857,36096,0.506667183,1.029383802,0.945517346,1.121237498,0.667372248,DB0031610037844_,0.404407296,0.028960373,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,14357,DB00588,10037844,432,16092,206,8262,0.397126447,1.076695482,0.907959008,1.280090364,0.566753679,DB0058810037844_,0.567830498,0.073896611,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,14358,DB00668,10037844,207,9884,83,4220,0.650808127,1.064804387,0.819319925,1.394396435,0.785277802,DB0066810037844_,0.241717736,0.062791108,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,epinephrine,DB00668
,14359,DB01075,10037844,694,19254,397,10700,0.652669553,0.971455443,0.85551633,1.104316683,0.786855599,DB0107510037844_,0.23971053,-0.028959875,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,14360,DB01098,10037844,249,7900,174,7035,0.015492718,1.274323232,1.042849114,1.559952517,0.050552552,DB0109810037844_,2.984741842,0.242415239,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,rosuvastatin,DB01098
,14361,DB01109,10037844,77,4335,53,4217,0.063063227,1.413222245,0.980522594,2.050310322,0.14906627,DB0110910037844_,1.903364309,0.345872377,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,heparin,DB01109
,14362,DB01211,10037844,58,1594,23,764,0.545678687,1.208546619,0.727571169,2.069434529,0.700401118,DB0121110037844_,0.356102083,0.189418496,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,clarithromycin,DB01211
,14363,DB09153,10037844,129,7670,90,5609,0.782734057,1.04818698,0.792757621,1.390854365,0.881806742,DB0915310037844_,0.12578236,0.047061986,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sodium chloride,DB09153
,14372,DB00668,10037423,50,10041,19,4284,0.79216635,1.122752853,0.649431192,2.019106128,0.88743507,DB0066810037423_,0.119419921,0.115783574,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,14374,DB09153,10037423,45,7754,37,5662,0.654018739,0.888095017,0.561234365,1.41317804,0.78790396,DB0915310037423_,0.238379074,-0.118676541,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,14376,DB00264,10022086,217,29390,95,24797,4.87482195160566e-08,1.927186608,1.506583772,2.480839561,9.45279058297443e-07,DB0026410022086_,13.87178565,0.656061223,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,14377,DB00343,10022086,40,8696,13,5082,0.064735578,1.798103213,0.94103798,3.667716797,0.151987376,DB0034310022086_,1.883957816,0.586732339,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,14379,DB00641,10022086,116,14008,55,12420,0.000109624,1.869947637,1.344072218,2.629190888,0.000862584,DB0064110022086_,7.055578123,0.625910429,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,14380,DB00758,10022086,79,8221,43,10031,1.47136734910853e-05,2.241621245,1.525259774,3.334001593,0.000152473,DB0075810022086_,8.788520071,0.807199374,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,14381,DB00410,10008479,32,1573,23,986,0.675027462,0.872157886,0.491394244,1.570607346,0.802945891,DB0041010008479_,0.21946795,-0.136784809,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,mupirocin,DB00410
,14382,DB00437,10008479,95,6826,116,11430,0.026396519,1.371280133,1.032609185,1.817345829,0.076636938,DB0043710008479_,2.568676105,0.315744707,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,14383,DB01060,10008479,105,8482,47,5034,0.128416534,1.325860198,0.929640504,1.915790889,0.253401044,DB0106010008479_,1.372781891,0.282061455,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,14385,DB00437,10043607,65,6856,108,11438,1,1.004081486,0.725410628,1.380554794,1,DB0043710043607_,0,0.004073179,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,allopurinol,DB00437
,14386,DB01060,10043607,50,8537,44,5037,0.054494973,0.670523265,0.437416994,1.030928935,0.133445161,DB0106010043607_,2.014064664,-0.399696879,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,amoxicillin,DB01060
,14392,DB00065,10037153,203,9261,86,4871,0.10372406,1.241467457,0.957723413,1.62083318,0.216577584,DB0006510037153_,1.52980644,0.216294113,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,infliximab,DB00065
,14393,DB00563,10008531,220,46426,101,15247,0.006395172,0.71536405,0.562281765,0.915316169,0.024914348,DB0056310008531_,3.692311413,-0.334963705,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,14395,DB00635,10008531,340,32713,217,23577,0.167449225,1.12920214,0.948801879,1.346342592,0.307465016,DB0063510008531_,1.179393968,0.121511312,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,14397,DB00916,10008531,42,5281,21,2410,0.785221209,0.912720021,0.527153395,1.626137961,0.88348663,DB0091610008531_,0.12387912,-0.091326104,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,14401,DB01234,10008531,220,31405,241,32647,0.607118173,0.948949263,0.786275589,1.144808079,0.75003413,DB0123410008531_,0.287636566,-0.052399945,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,14402,DB08895,10008531,164,27950,27,6619,0.080030595,1.438415462,0.952365813,2.250960454,0.178452133,DB0889510008531_,1.723434878,0.363542134,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,14405,DB00635,10019211,1671,31382,555,23239,1.06864469246422e-64,2.229502838,2.021064039,2.462491357,1.08035868236239e-61,DB0063510019211_,140.3803976,0.801778618,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,14406,DB00843,10019211,52,2142,26,2147,0.004032772,2.004348488,1.223749613,3.357274949,0.017195912,DB0084310019211_,4.063083597,0.695319064,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,donepezil,DB00843
,14407,DB00916,10019211,175,5148,52,2379,0.005661107,1.55513426,1.130394513,2.170843256,0.022597144,DB0091610019211_,3.789931759,0.441561883,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,metronidazole,DB00916
,14409,DB01112,10019211,49,1096,6,573,0.000126199,4.266894138,1.811086064,12.26376385,0.000973482,DB0111210019211_,6.934631236,1.450886195,female,10019211,Headache,10029205,Nervous system disorders,Nerv,cefuroxime,DB01112
,14410,DB01190,10019211,140,4794,30,2255,3.84057664376931e-05,2.19490167,1.465892666,3.385263251,0.000352485,DB0119010019211_,7.950502235,0.786137248,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,clindamycin,DB01190
,14412,DB00404,10020772,254,19638,104,9758,0.101540689,1.213533354,0.960952168,1.541736499,0.213232172,DB0040410020772_,1.545373697,0.193536231,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,alprazolam,DB00404
,14413,DB00451,10020772,630,46641,213,15206,0.657864834,0.96428926,0.823325544,1.13295888,0.790924263,DB0045110020772_,0.234553064,-0.036363967,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,14414,DB00563,10020772,319,46327,137,15211,0.010389638,0.764532198,0.623365542,0.941765401,0.036698467,DB0056310020772_,3.305020287,-0.268491138,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,methotrexate,DB00563
,14416,DB00635,10020772,440,32613,275,23519,0.067068537,1.153815677,0.9892295,1.347695296,0.156091419,DB0063510020772_,1.857313423,0.14307443,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,prednisone,DB00635
,14417,DB00843,10020772,31,2163,24,2149,0.416091877,1.28323008,0.726286509,2.293167068,0.585350155,DB0084310020772_,0.535545055,0.249380399,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,donepezil,DB00843
,14418,DB00916,10020772,48,5275,17,2414,0.42154559,1.292050131,0.728003174,2.401833558,0.590619964,DB0091610020772_,0.526582507,0.256230206,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,metronidazole,DB00916
,14421,DB01190,10020772,41,4893,21,2264,0.68321338,0.903387179,0.520231125,1.61312016,0.808457376,DB0119010020772_,0.212627322,-0.101604048,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,clindamycin,DB01190
,14422,DB01234,10020772,279,31346,273,32615,0.493978347,1.063380413,0.896023399,1.262053764,0.656664181,DB0123410020772_,0.420582532,0.061452902,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,dexamethasone,DB01234
,14423,DB08895,10020772,277,27837,56,6590,0.326673815,1.170988176,0.874750238,1.591923201,0.495078566,DB0889510020772_,0.70303881,0.157847987,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,tofacitinib,DB08895
,14426,DB00916,10028813,323,5000,83,2348,5.16695565393359e-07,1.827352123,1.423957177,2.366800306,7.98391344403227e-06,DB0091610028813_,11.73808186,0.602867992,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,metronidazole,DB00916
,14427,DB00951,10028813,50,602,27,538,0.044491903,1.654303562,0.999923868,2.789768286,0.114569648,DB0095110028813_,2.166572362,0.503380112,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,isoniazid,DB00951
,14428,DB01112,10028813,47,1098,17,562,0.280402209,1.414817511,0.788830223,2.653814584,0.444252558,DB0111210028813_,0.811362054,0.347000555,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cefuroxime,DB01112
,14429,DB01190,10028813,252,4682,94,2191,0.066551441,1.254456236,0.980401198,1.616195644,0.15514209,DB0119010028813_,1.863413871,0.2267022,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,clindamycin,DB01190
,14431,DB00404,10028836,134,19758,26,9836,1.86441114825732e-06,2.565635157,1.674969172,4.072934681,2.49077748574047e-05,DB0040410028836_,10.60033056,0.942206073,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,14433,DB00635,10028836,184,32869,68,23726,9.93105739328383e-07,1.95316778,1.470477909,2.62053406,1.42216204621338e-05,DB0063510028836_,11.16074718,0.669452557,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,14439,DB01234,10028836,106,31519,57,32831,4.09565656910682e-05,1.93702532,1.390420228,2.722988043,0.000372284,DB0123410028836_,7.895854599,0.661153456,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,14440,DB08895,10028836,266,27848,52,6594,0.223510993,1.211240591,0.895781843,1.66558514,0.377897691,DB0889510028836_,0.97313178,0.191645116,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,14442,DB00404,10047700,599,19293,190,9672,2.00825776956999e-08,1.580459953,1.337708416,1.874016269,4.20111862102245e-07,DB0040410047700_,14.68274482,0.457715914,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,14444,DB00916,10047700,216,5107,56,2375,6.21849247483702e-05,1.79363571,1.325381272,2.461904092,0.000531186,DB0091610047700_,7.540398315,0.584244683,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,metronidazole,DB00916
,14447,DB01190,10047700,162,4772,54,2231,0.037280753,1.402502483,1.020236175,1.953770776,0.100130728,DB0119010047700_,2.301278663,0.338258129,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,clindamycin,DB01190
,14448,DB08895,10047700,453,27661,45,6601,5.72525977797871e-10,2.40229338,1.763682457,3.344539714,1.66102045545442e-08,DB0889510047700_,17.9132486,0.876423856,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,14450,DB00335,10007559,67,8399,56,5409,0.164169842,0.770532672,0.531312964,1.121087912,0.302980817,DB0033510007559_,1.194085784,-0.260673222,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,atenolol,DB00335
,14451,DB01104,10007559,85,15378,57,7229,0.046683612,0.701003618,0.494733637,0.999713671,0.118845397,DB0110410007559_,2.129931812,-0.355242231,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,sertraline,DB01104
,14452,DB00175,10008469,44,8087,17,6089,0.019180362,1.948677537,1.089914543,3.641666926,0.059819152,DB0017510008469_,2.816429394,0.667150956,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,14453,DB00335,10008469,61,8405,38,5427,0.917916042,1.036497918,0.679114262,1.599991487,0.963555238,DB0033510008469_,0.037125462,0.035847644,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,14455,DB00641,10008469,98,14026,55,12420,0.007178495,1.577765392,1.121672074,2.238883616,0.027322145,DB0064110008469_,3.600057748,0.456009537,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,14456,DB01104,10008469,119,15344,30,7256,0.001453569,1.875744811,1.246679074,2.903843354,0.00749452,DB0110410008469_,4.893583138,0.629005813,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,14457,DB00335,10013968,372,8094,210,5255,0.118479936,1.150043597,0.964889299,1.373683699,0.238914086,DB0033510013968_,1.431651263,0.139799852,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atenolol,DB00335
,14458,DB00412,10013968,28,1036,30,1356,0.503264575,1.221514719,0.698397031,2.130452905,0.66441715,DB0041210013968_,0.408845089,0.200091661,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosiglitazone,DB00412
,14461,DB00641,10034474,31,14093,25,12450,0.789459593,1.095401207,0.625581625,1.93622636,0.885865533,DB0064110034474_,0.121190109,0.091120696,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,simvastatin,DB00641
,14464,DB00656,10007515,186,11827,112,6507,0.464311167,0.913701071,0.717451336,1.168043077,0.631450223,DB0065610007515_,0.459736164,-0.090251816,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,trazodone,DB00656
,14465,DB00661,10007515,57,3471,38,1557,0.072838193,0.67291138,0.43654824,1.04755939,0.166258687,DB0066110007515_,1.794210347,-0.396141637,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,verapamil,DB00661
,14466,DB00668,10007515,93,9998,86,4217,3.77490804830408e-07,0.456135306,0.335717018,0.620270092,6.00262904111753e-06,DB0066810007515_,12.02331301,-0.78496579,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,epinephrine,DB00668
,14468,DB01390,10007515,39,1370,51,1466,0.391813129,0.818348012,0.521537262,1.275391559,0.561686788,DB0139010007515_,0.576810901,-0.200467591,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,sodium bicarbonate,DB01390
,14481,DB00656,10010264,244,11769,126,6493,0.583377442,1.068380741,0.856268919,1.338336716,0.731448009,DB0065610010264_,0.312729135,0.066144176,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,14482,DB00661,10010264,57,3471,11,1584,0.007802992,2.364408556,1.223021963,5.013747461,0.029191809,DB0066110010264_,3.533867125,0.860527909,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,verapamil,DB00661
,14483,DB00668,10010264,85,10006,31,4272,0.478079504,1.170631595,0.766333221,1.830798759,0.643387336,DB0066810010264_,0.441008347,0.157543428,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,14485,DB01164,10010264,32,6492,39,7897,1,0.998088492,0.604549676,1.636968753,1,DB0116410010264_,0,-0.001913337,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,14490,DB00656,10038695,86,11927,46,6573,0.927392839,1.030321731,0.711167117,1.509723646,0.969418814,DB0065610038695_,0.031058548,0.029871114,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,14491,DB00661,10038695,38,3490,20,1575,0.570814275,0.857487966,0.484758692,1.560793698,0.721268016,DB0066110038695_,0.326744482,-0.153748134,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,verapamil,DB00661
,14492,DB01164,10038695,29,6495,54,7882,0.076143229,0.651740871,0.399632072,1.043282033,0.171720663,DB0116410038695_,1.761886173,-0.428108233,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium chloride,DB01164
,14493,DB01390,10038695,37,1372,24,1493,0.052388886,1.677320529,0.971333075,2.947191231,0.129494252,DB0139010038695_,2.044118785,0.517197597,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium bicarbonate,DB01390
,14506,DB00987,10000880,49,2055,70,2858,0.92525552,0.973530909,0.658562912,1.42947321,0.967973417,DB0098710000880_,0.032550654,-0.026825704,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cytarabine,DB00987
,14507,DB00997,10000880,107,5224,68,3446,0.876061832,1.037974297,0.756348993,1.432720798,0.946904013,DB0099710000880_,0.05455755,0.037271022,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,doxorubicin,DB00997
,14512,DB00997,10007636,66,5265,38,3476,0.546097189,1.146698907,0.756064203,1.761246351,0.700742839,DB0099710007636_,0.355614307,0.136887299,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,doxorubicin,DB00997
,14514,DB00531,10021789,103,7149,107,6409,0.296842161,0.862985847,0.650503628,1.144397804,0.462683897,DB0053110021789_,0.770711185,-0.147356988,NA,10021789,Infection,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,14516,DB00987,10021789,22,2082,39,2889,0.433568299,0.782790944,0.440641914,1.358004049,0.602073209,DB0098710021789_,0.507376232,-0.244889613,NA,10021789,Infection,10021881,Infections and infestations,Infec,cytarabine,DB00987
,14517,DB00997,10021789,50,5281,36,3478,0.739966655,0.914715033,0.582796133,1.448598929,0.85051593,DB0099710021789_,0.161912138,-0.089142701,NA,10021789,Infection,10021881,Infections and infestations,Infec,doxorubicin,DB00997
,14528,DB00987,10003997,36,2068,64,2864,0.260435356,0.779051804,0.500872597,1.195092989,0.421874301,DB0098710003997_,0.863047874,-0.249677735,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,cytarabine,DB00987
,14537,DB00694,10035664,18,616,35,736,0.12104649,0.614678584,0.324288355,1.1280304,0.242943305,DB0069410035664_,1.414927175,-0.486655775,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,daunorubicin,DB00694
,14544,DB00497,10029148,59,19208,45,16330,0.622921594,1.114634224,0.743055931,1.68221009,0.763084033,DB0049710029148_,0.270387119,0.108526301,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,oxycodone,DB00497
,14547,DB08910,10020100,84,16660,48,17440,0.000851247,1.831887215,1.269201699,2.670784748,0.004819607,DB0891010020100_,5.335062846,0.605346701,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pomalidomide,DB08910
,14548,DB00252,10013709,194,2038,157,1751,0.614687636,1.061662114,0.847262019,1.33185277,0.75615505,DB0025210013709_,0.279508832,0.059835712,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,phenytoin,DB00252
,14551,DB00215,10002034,148,10955,76,5200,0.614348976,0.924362036,0.694881833,1.238065433,0.755840897,DB0021510002034_,0.279924379,-0.07865147,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,citalopram,DB00215
,14553,DB11133,10002034,53,2378,36,1538,0.826976076,0.952207677,0.608713897,1.504623432,0.908778216,DB1113310002034_,0.095654201,-0.04897212,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,omega-3 fatty acids,DB11133
,14554,DB00215,10016173,367,10736,163,5113,0.478824067,1.072282855,0.886458193,1.301563328,0.644060791,DB0021510016173_,0.439962161,0.069789885,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,14555,DB00813,10016173,229,10343,121,10047,4.26626737517436e-08,1.838336952,1.465869749,2.314853973,8.35609820837989e-07,DB0081310016173_,13.99510405,0.608861332,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,14557,DB11133,10016173,83,2348,56,1518,0.85976524,0.958255078,0.670168378,1.378747193,0.933724304,DB1113310016173_,0.068574062,-0.042641276,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,omega-3 fatty acids,DB11133
,14560,DB00451,10039020,72,47199,63,15356,3.04377469224029e-08,0.371830862,0.261344336,0.53025604,6.13775357004495e-07,DB0045110039020_,14.30363684,-0.989316201,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,14562,DB00497,10039020,96,19171,53,16322,0.010688933,1.542118207,1.090724891,2.200858655,0.037546253,DB0049710039020_,3.282181705,0.43315693,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,14563,DB00813,10039020,22,10550,63,10105,3.2234585003178e-06,0.334488152,0.195826494,0.551640447,4.03277518709441e-05,DB0081310039020_,10.11847069,-1.095153819,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,fentanyl,DB00813
,14568,DB08908,10016825,1022,9651,221,3058,3.55509496887213e-07,1.465309913,1.258244853,1.711994051,5.68923417088608e-06,DB0890810016825_,12.07693491,0.382066765,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,dimethyl fumarate,DB08908
,14569,DB00169,10005557,261,38430,147,18028,0.078841304,0.832932591,0.677373896,1.027401693,0.176398722,DB0016910005557_,1.73500838,-0.182802563,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,14570,DB00213,10005557,114,18781,89,13332,0.520562517,0.909270657,0.68240583,1.214760271,0.679679962,DB0021310005557_,0.386133235,-0.095112477,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,pantoprazole,DB00213
,14571,DB00316,10005557,302,65172,174,36779,0.848285796,0.979471689,0.809744855,1.187813669,0.924235944,DB0031610005557_,0.07878789,-0.020741946,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,acetaminophen,DB00316
,14572,DB00341,10005557,72,11333,36,5032,0.601035614,0.888039278,0.586419119,1.366243515,0.745334479,DB0034110005557_,0.293922197,-0.118739305,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,cetirizine,DB00341
,14574,DB00455,10005557,40,9361,28,5090,0.310718618,0.776811915,0.466818477,1.309103184,0.478119592,DB0045510005557_,0.737894386,-0.252557024,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,loratadine,DB00455
,14575,DB00480,10005557,217,67211,237,67425,0.372086094,0.91854716,0.760255832,1.109315726,0.541768895,DB0048010005557_,0.612915761,-0.084962031,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,lenalidomide,DB00480
,14577,DB00787,10005557,58,16942,75,17173,0.165737777,0.783884941,0.546241537,1.119991404,0.305113985,DB0078710005557_,1.18706985,-0.243493029,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,acyclovir,DB00787
,14578,DB00904,10005557,126,22943,84,14372,0.670018108,0.939635039,0.706738839,1.254653607,0.799758272,DB0090410005557_,0.223445757,-0.062263736,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,ondansetron,DB00904
,14579,DB01015,10005557,40,9847,51,9330,0.172310194,0.743149391,0.478173271,1.1478508,0.313904664,DB0101510005557_,1.158665959,-0.296858189,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,14580,DB01234,10005557,193,31432,231,32657,0.157537724,0.868062189,0.712820579,1.05617433,0.294221904,DB0123410005557_,1.22342102,-0.141491921,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,dexamethasone,DB01234
,14581,DB01307,10005557,172,2352,108,1961,0.025646838,1.327754365,1.029645275,1.718109374,0.074927991,DB0130710005557_,2.591227746,0.283489068,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,insulin detemir,DB01307
,14583,DB09153,10005557,43,7756,35,5664,0.647011709,0.897201412,0.560090497,1.446183295,0.782313016,DB0915310005557_,0.245500343,-0.108474902,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,sodium chloride,DB09153
,14584,DB11089,10005557,71,10104,57,8350,0.929068345,1.0293844,0.715281716,1.487219268,0.97064913,DB1108910005557_,0.029790225,0.028960953,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,docusate,DB11089
,14586,DB00213,10000891,50,18845,52,13369,0.056040184,0.682155109,0.452983392,1.026342188,0.136169747,DB0021310000891_,1.993853033,-0.382498214,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,14593,DB00213,10007515,107,18788,120,13301,0.000692356,0.63128101,0.481342105,0.826951399,0.004054038,DB0021310007515_,5.508041843,-0.460004175,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,14597,DB00836,10007515,95,5440,150,3925,2.51643042971128e-09,0.456987927,0.348450981,0.596918615,6.44682006286169e-08,DB0083610007515_,16.55709375,-0.783098307,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,loperamide,DB00836
,14599,DB05676,10023232,212,46917,74,25255,0.001195189,1.542122113,1.17769652,2.03849637,0.006387867,DB0567610023232_,5.053354813,0.433159464,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,14600,DB05676,10048959,328,46801,129,25200,0.0022645,1.369076512,1.11277514,1.692711293,0.010763541,DB0567610048959_,4.531590659,0.314136434,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,14601,DB00316,10013781,312,65162,122,36831,0.000448268,1.445480742,1.168398792,1.797747808,0.002819171,DB0031610013781_,5.871312458,0.368441959,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,14602,DB01050,10013781,89,18019,36,9335,0.220350342,1.280801207,0.859775457,1.943987969,0.373876561,DB0105010013781_,0.983829587,0.247485825,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,14607,DB00455,10002855,209,9192,63,5055,1.61920723633382e-05,1.824317044,1.367213122,2.463408916,0.000165606,DB0045510002855_,8.70589626,0.601205694,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,loratadine,DB00455
,14609,DB00455,10019303,57,9344,21,5097,0.153272907,1.480560992,0.882605273,2.574404465,0.288563432,DB0045510019303_,1.242840348,0.392421065,NA,10019303,Heart rate increased,10022891,Investigations,Inv,loratadine,DB00455
,14610,DB00471,10019303,87,14102,26,5439,0.29248424,1.290540666,0.823530409,2.086824819,0.4580795,DB0047110019303_,0.780712529,0.255061252,NA,10019303,Heart rate increased,10022891,Investigations,Inv,montelukast,DB00471
,14612,DB00455,10021097,146,9255,82,5036,0.834109759,0.968807979,0.732508392,1.288668693,0.913866659,DB0045510021097_,0.090070606,-0.03168885,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,loratadine,DB00455
,14613,DB00471,10021097,149,14040,69,5396,0.223659635,0.829965712,0.618660384,1.122741863,0.378112523,DB0047110021097_,0.972563448,-0.186370889,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,montelukast,DB00471
,14614,DB00783,10021097,82,16632,7,366,0.003320347,0.257816222,0.118508698,0.665976065,0.014685398,DB0078310021097_,4.220901579,-1.355508265,male,10021097,Hypotension,10047065,Vascular disorders,Vasc,estradiol,DB00783
,14619,DB00115,10056819,62,18363,36,10436,0.916485386,0.978757076,0.638438466,1.520706732,0.962707173,DB0011510056819_,0.038005992,-0.021471802,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,14620,DB00169,10056819,139,38552,55,18120,0.316056536,1.187836637,0.862900911,1.655050692,0.483713998,DB0016910056819_,0.72626146,0.172133701,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,14622,DB00635,10056819,87,32966,33,23761,0.001527394,1.900189444,1.258947587,2.930502177,0.007807012,DB0063510056819_,4.852733012,0.641953588,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,14627,DB01373,10056819,76,22644,19,7362,0.340741852,1.300454663,0.777932358,2.279118512,0.509972929,DB0137310056819_,0.673397635,0.262713944,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,14630,DB00335,10000060,66,8400,27,5438,0.043387941,1.582436191,0.995737323,2.579806807,0.112433404,DB0033510000060_,2.185394201,0.458965553,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,14631,DB00381,10000060,233,29127,129,22758,0.001683988,1.411240826,1.132441469,1.765042989,0.008445645,DB0038110000060_,4.774104321,0.344469336,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,14633,DB08877,10000060,58,3231,27,3202,0.000982213,2.128620505,1.322614619,3.505493621,0.005423267,DB0887710000060_,5.217056892,0.75547412,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,ruxolitinib,DB08877
,14634,DB01039,10013573,110,2863,84,2967,0.040862283,1.357018036,1.007264958,1.833627186,0.107368648,DB0103910013573_,2.23148706,0.305289672,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,fenofibrate,DB01039
,14635,DB08877,10013573,176,3113,116,3113,0.0006262,1.51713577,1.186744525,1.94534877,0.003734111,DB0887710013573_,5.590245499,0.416824195,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ruxolitinib,DB08877
,14636,DB00335,10016256,577,7889,337,5128,0.132029388,1.112961085,0.966719595,1.282743825,0.258685287,DB0033510016256_,1.352143065,0.107024108,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,14637,DB01039,10016256,184,2789,174,2877,0.44558543,1.090810025,0.87584072,1.358995767,0.613465694,DB0103910016256_,0.488630935,0.086920562,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,14638,DB00996,10027175,532,38421,210,22215,2.25456527487399e-06,1.464762868,1.245084455,1.728341901,2.9461222097968e-05,DB0099610027175_,10.43243566,0.381693365,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,14640,DB08877,10027175,45,3244,27,3202,0.043847741,1.64495551,0.996040417,2.764389683,0.11326597,DB0887710027175_,2.178016513,0.497713338,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ruxolitinib,DB08877
,14642,DB08877,10041349,40,3249,28,3201,0.180789116,1.407387101,0.844592434,2.375033266,0.324866758,DB0887710041349_,1.124340156,0.341734866,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ruxolitinib,DB08877
,14643,DB00472,10041466,42,10717,13,4299,0.458421608,1.29593891,0.681609096,2.634099878,0.625791326,DB0047210041466_,0.468738309,0.25923546,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,14644,DB00996,10041466,128,38825,64,22361,0.368827412,1.151909102,0.846399649,1.581094492,0.538470813,DB0099610041466_,0.619021985,0.141420655,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,14655,DB00480,10055798,135,67293,179,67483,0.015037419,0.756323314,0.60019041,0.951223436,0.049416584,DB0048010055798_,3.007469199,-0.279286331,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,lenalidomide,DB00480
,14656,DB08910,10013573,411,16333,319,17169,6.05645981764667e-05,1.354329253,1.165346827,1.575113834,0.000519987,DB0891010013573_,7.561706582,0.303306316,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,14657,DB00641,10013710,132,13992,214,12261,2.54915820176015e-08,0.540531507,0.431172034,0.675570841,5.22860892183111e-07,DB0064110013710_,14.46395039,-0.615202351,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,14659,DB00996,10013710,361,38592,279,22146,0.000235561,0.742532135,0.632777617,0.872004208,0.001651362,DB0099610013710_,6.406155059,-0.29768913,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,14660,DB01234,10013710,69,31556,92,32796,0.133505882,0.779476125,0.561852417,1.077143759,0.260636467,DB0123410013710_,1.344628688,-0.24913322,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,14662,DB00381,10037377,163,29197,152,22735,0.111159004,0.835033366,0.664874899,1.049256957,0.22783067,DB0038110037377_,1.479152603,-0.180283595,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,14663,DB00641,10037377,70,14054,96,12379,0.004917224,0.642279287,0.464648892,0.884044318,0.020201505,DB0064110037377_,3.901998161,-0.442732044,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,14664,DB00868,10037377,36,2948,22,1624,0.681713502,0.901466296,0.514123068,1.614447752,0.807536871,DB0086810037377_,0.213766564,-0.103732623,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,benzonatate,DB00868
,14665,DB08910,10037377,80,16664,128,17360,0.00270692,0.651115267,0.485722974,0.868378053,0.012432273,DB0891010037377_,4.387459528,-0.429068591,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,14666,DB00381,10042772,247,29113,188,22699,0.846136015,1.024376587,0.843224806,1.246067379,0.922658584,DB0038110042772_,0.080496012,0.02408422,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,14668,DB00996,10042772,277,38676,176,22249,0.304178181,0.905394287,0.746253324,1.100828713,0.470811653,DB0099610042772_,0.753297152,-0.099384753,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,14669,DB01234,10042772,208,31417,212,32676,0.844857271,1.020452948,0.838161734,1.242268119,0.921659279,DB0123410042772_,0.081579669,0.020246596,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,14670,DB08910,10042772,77,16667,62,17426,0.126963416,1.298477748,0.916631095,1.845807882,0.251411284,DB0891010042772_,1.380665098,0.261192616,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,14671,DB00641,10043607,113,14011,111,12364,0.45967702,0.898353707,0.684345181,1.179444475,0.627130536,DB0064110043607_,0.466600568,-0.107191405,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,simvastatin,DB00641
,14673,DB00996,10043607,282,38671,225,22200,0.000295636,0.719533012,0.601259408,0.861838096,0.00199407,DB0099610043607_,6.217577748,-0.329152872,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,gabapentin,DB00996
,14674,DB01234,10043607,534,31091,648,32240,0.008201303,0.854531427,0.759788053,0.960773753,0.030405821,DB0123410043607_,3.493121212,-0.157201999,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,dexamethasone,DB01234
,14675,DB08910,10043607,264,16480,327,17161,0.037996756,0.840706161,0.711107059,0.993212633,0.101612038,DB0891010043607_,2.286593269,-0.173513073,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,pomalidomide,DB08910
,14676,DB00158,10000087,214,16601,82,8022,0.080443417,1.261045446,0.971834783,1.649615716,0.179153163,DB0015810000087_,1.71951418,0.231941096,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,14677,DB00169,10000087,559,38132,176,17999,1.68860289004983e-06,1.499184344,1.262099782,1.787890041,2.28611521838577e-05,DB0016910000087_,10.6860715,0.404921189,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,14678,DB00213,10000087,320,18575,129,13292,1.86209391775402e-08,1.775058833,1.440603514,2.197559592,3.92660558589366e-07,DB0021310000087_,14.75032032,0.573833568,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,14679,DB00230,10000087,226,19448,54,8597,2.70674934686899e-05,1.850028229,1.367809352,2.540929478,0.000258999,DB0023010000087_,8.258688026,0.615200898,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,14680,DB00476,10000087,216,17041,44,6133,0.000378972,1.766793872,1.270758448,2.505702821,0.002453515,DB0047610000087_,6.010233646,0.569166532,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,14681,DB00635,10000087,374,32679,157,23637,4.61614585948483e-09,1.723018907,1.425127598,2.09120522,1.11778345386051e-07,DB0063510000087_,16.00674799,0.544077931,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,14682,DB00863,10000087,226,10447,76,5764,0.000156982,1.640646528,1.257109682,2.161094599,0.001173071,DB0086310000087_,6.748130245,0.495090389,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,14683,DB00904,10000087,372,22697,150,14306,2.87304955351705e-06,1.563134016,1.288216697,1.904510279,3.6508633074303e-05,DB0090410000087_,10.2179618,0.446692791,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,14685,DB01068,10000087,180,13583,45,6795,1.26289999238921e-05,2.000971003,1.434291102,2.843364925,0.000133242,DB0106810000087_,8.923345311,0.693632564,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,14686,DB01075,10000087,216,19732,75,11022,0.000347477,1.608701443,1.230288048,2.123139074,0.002280508,DB0107510000087_,6.083357067,0.475427296,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,14687,DB01076,10000087,307,25440,218,25365,0.000131803,1.404089841,1.175436673,1.679543028,0.001009303,DB0107610000087_,6.898494991,0.339389293,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,14688,DB01224,10000087,61,8047,37,5880,0.412167366,1.204659412,0.786740074,1.867208113,0.581541062,DB0122410000087_,0.542073696,0.186196881,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,quetiapine,DB01224
,14690,DB00213,10012735,1255,17640,635,12786,3.37483775357538e-13,1.43252028,1.297502102,1.582790765,1.6114007330196e-11,DB0021310012735_,24.8513322,0.359435327,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,14691,DB00230,10012735,722,18952,240,8411,0.00010241,1.335146712,1.14936653,1.555040754,0.000814603,DB0023010012735_,7.112809366,0.289041183,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,14692,DB00953,10012735,62,1635,6,226,0.567643338,1.428104448,0.610363842,4.087413736,0.718752656,DB0095310012735_,0.330237992,0.356348004,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,rizatriptan,DB00953
,14693,DB01224,10012735,210,7898,111,5806,0.005073343,1.39073961,1.096856021,1.771137469,0.020698925,DB0122410012735_,3.877673526,0.329835699,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,quetiapine,DB01224
,14694,DB06723,10012735,82,948,33,577,0.057058672,1.51203951,0.983447703,2.370768595,0.137892447,DB0672310012735_,1.981281266,0.413459409,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,aluminum hydroxide,DB06723
,14696,DB00169,10017822,42,38649,29,18146,0.125844417,0.679970258,0.413522176,1.132294882,0.249835384,DB0016910017822_,1.38695304,-0.385706221,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,14697,DB00213,10017822,45,18850,35,13386,0.733633501,0.913031091,0.573657035,1.463969469,0.845547513,DB0021310017822_,0.167770917,-0.090985345,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,14700,DB00635,10017822,42,33011,33,23761,0.726274179,0.916098987,0.566696482,1.492256877,0.839771992,DB0063510017822_,0.174624862,-0.087630856,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,14702,DB00904,10017822,43,23026,14,14442,0.029704408,1.926377717,1.033322751,3.813970884,0.084054298,DB0090410017822_,2.476292289,0.655641409,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,14706,DB01076,10017822,34,25713,21,25562,0.104701084,1.609515758,0.907352806,2.919225178,0.218051793,DB0107610017822_,1.52302266,0.475933363,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,14710,DB00158,10042209,97,16718,9,8095,7.5914380075502e-09,5.218894732,2.636328594,11.76059165,1.7518959440602e-07,DB0015810042209_,15.55739705,1.652285642,female,10042209,Stress,10037175,Psychiatric disorders,Psych,folic acid,DB00158
,14711,DB00169,10042209,221,38470,32,18143,1.38077498675162e-12,3.256952888,2.240298558,4.8807626,6.0755802074279e-11,DB0016910042209_,23.52415853,1.180792061,female,10042209,Stress,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,14712,DB00213,10042209,75,18820,24,13397,0.000454498,2.224460977,1.387701291,3.686505432,0.002852212,DB0021310042209_,5.859660413,0.799514629,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,14713,DB00230,10042209,178,19496,33,8618,8.34971502901697e-07,2.384273299,1.63577068,3.573359546,1.2223461962557e-05,DB0023010042209_,11.31215334,0.868894381,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,14714,DB00476,10042209,122,17135,11,6166,1.81330696745365e-07,3.99103495,2.151677267,8.21003881,3.10506668661362e-06,DB0047610042209_,12.68247537,1.384050583,female,10042209,Stress,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,14715,DB00635,10042209,121,32932,36,23758,8.64270256903782e-07,2.424733874,1.658475177,3.624465907,1.26102379698673e-05,DB0063510042209_,11.28100154,0.885721776,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,14716,DB00863,10042209,59,10614,13,5827,0.001812262,2.491459795,1.349516938,4.956392763,0.008972555,DB0086310042209_,4.713584798,0.912868802,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,ranitidine,DB00863
,14717,DB00904,10042209,81,22988,11,14445,1.95835898599506e-08,4.626949527,2.452671094,9.63827319,4.10981764046947e-07,DB0090410042209_,14.70471699,1.531897802,female,10042209,Stress,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,14719,DB01068,10042209,93,13670,39,6801,0.404742903,1.186349098,0.807000671,1.773591858,0.574497607,DB0106810042209_,0.554259348,0.170880606,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,14720,DB01075,10042209,54,19894,15,11082,0.016314535,2.005346777,1.114727896,3.828162375,0.052623334,DB0107510042209_,2.944595643,0.695817002,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,14721,DB01076,10042209,117,25630,39,25544,2.909755491643e-10,2.990056303,2.063885787,4.415513963,8.83684842262696e-09,DB0107610042209_,18.54433554,1.095292218,female,10042209,Stress,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,14722,DB01224,10042209,42,8066,18,5899,0.066029496,1.706396138,0.960073067,3.152792012,0.154198862,DB0122410042209_,1.869512197,0.534383625,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,14724,DB08908,10042209,93,10580,12,3267,0.002473849,2.393109266,1.304664198,4.803702444,0.011570305,DB0890810042209_,4.459313346,0.872593468,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,dimethyl fumarate,DB08908
,14725,DB00158,10048393,48,16767,13,8091,0.074326652,1.781704501,0.949448473,3.587089987,0.168740373,DB0015810048393_,1.779394001,0.577570491,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,14726,DB00169,10048393,489,38202,130,18045,1.40533696393523e-09,1.776774386,1.460194424,2.174859502,3.78405892020728e-08,DB0016910048393_,17.08988352,0.574799578,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,14727,DB00213,10048393,84,18811,20,13401,1.88743652173803e-06,2.991958027,1.819365859,5.148614323,2.51642246887568e-05,DB0021310048393_,10.59008723,1.095928031,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,14728,DB00230,10048393,131,19543,29,8622,0.00052743,1.992879125,1.323540267,3.094308188,0.003225196,DB0023010048393_,5.736761561,0.68958039,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,14729,DB00476,10048393,190,17067,34,6143,6.86939294922675e-05,2.011407436,1.388819187,2.992659049,0.000577521,DB0047610048393_,7.456765459,0.698834694,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,14730,DB00635,10048393,135,32918,39,23755,7.84806442799109e-08,2.497927314,1.736967606,3.666478367,1.45374470394465e-06,DB0063510048393_,13.44136778,0.915461314,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,14731,DB00863,10048393,47,10626,16,5824,0.112950073,1.609969859,0.895542575,3.044750977,0.230513038,DB0086310048393_,1.467447855,0.476215458,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,14732,DB00904,10048393,103,22966,19,14437,3.70580611690093e-08,3.407703063,2.074313506,5.89109379,7.34316726594353e-07,DB0090410048393_,14.12432539,1.226038476,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,14734,DB01068,10048393,147,13616,33,6807,1.04395022883491e-05,2.226870765,1.516194388,3.358826434,0.000112668,DB0106810048393_,9.09106729,0.800597356,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,14735,DB01075,10048393,70,19878,13,11084,7.53698178526494e-05,3.002374929,1.645884482,5.919695358,0.000625543,DB0107510048393_,7.37688999,1.099403619,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,14736,DB01076,10048393,108,25639,48,25535,1.71867553852342e-06,2.240980018,1.580099292,3.219097082,2.3172806632515e-05,DB0107610048393_,10.67253109,0.806913278,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,14742,DB00321,10000059,83,7364,23,2827,0.190444987,1.385276161,0.86218191,2.309240817,0.337128093,DB0032110000059_,1.087292322,0.325899514,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,amitriptyline,DB00321
,14743,DB00682,10000059,326,19133,137,16227,1.22725685761749e-12,2.018064678,1.646193826,2.485000045,5.45828198011432e-11,DB0068210000059_,23.63130194,0.702138972,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,14744,DB08877,10000059,60,3229,39,3190,0.043160105,1.519775484,0.995642117,2.343570703,0.111981256,DB0887710000059_,2.18942378,0.418562616,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ruxolitinib,DB08877
,14745,DB00321,10016256,406,7041,136,2714,0.182878808,1.150679891,0.940297419,1.415010664,0.327524014,DB0032110016256_,1.116193902,0.140352977,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,14746,DB00829,10016256,475,7577,172,4282,6.0644304820968e-07,1.56062947,1.302598666,1.876654854,9.19282325385895e-06,DB0082910016256_,11.59708746,0.445089246,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,14747,DB00682,10019211,1548,17911,502,15862,2.30733941408813e-92,2.730601713,2.461982823,3.032754558,4.18264941374528e-89,DB0068210019211_,203.4991284,1.004521993,female,10019211,Headache,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,14748,DB00829,10019211,408,7644,115,4339,6.96954532689152e-12,2.013764737,1.627700705,2.50735248,2.74243261852311e-10,DB0082910019211_,22.01700559,0.700005974,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,14749,DB08877,10019211,187,3102,113,3116,2.54026084451774e-05,1.662196186,1.30174965,2.130116322,0.00024494,DB0887710019211_,8.314495594,0.508139732,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ruxolitinib,DB08877
,14750,DB00321,10037087,134,7313,25,2825,0.00045832,2.070436943,1.340072298,3.320478197,0.002871398,DB0032110037087_,5.852956407,0.727759669,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,amitriptyline,DB00321
,14751,DB00682,10037087,311,19148,145,16219,1.48925337732957e-09,1.816706656,1.48524511,2.230653811,3.99031855485297e-08,DB0068210037087_,17.03680968,0.597025332,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,14752,DB00829,10037087,121,7931,40,4414,0.003676754,1.683499345,1.166198964,2.476064075,0.01594514,DB0082910037087_,4.138601227,0.520874571,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,diazepam,DB00829
,14753,DB08877,10037087,74,3215,42,3187,0.004736892,1.746403052,1.176077,2.623366437,0.019579999,DB0887710037087_,3.933246717,0.557558274,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ruxolitinib,DB08877
,14754,DB00321,10047899,133,7314,35,2815,0.045674425,1.462552133,0.998440759,2.193284808,0.116860638,DB0032110047899_,2.146773183,0.380182946,NA,10047899,Weight increased,10022891,Investigations,Inv,amitriptyline,DB00321
,14755,DB00682,10047899,421,19038,216,16148,1.47807716318365e-09,1.653173805,1.397750886,1.959743061,3.964414105539e-08,DB0068210047899_,17.04332267,0.502696959,NA,10047899,Weight increased,10022891,Investigations,Inv,warfarin,DB00682
,14756,DB00829,10047899,123,7929,44,4410,0.011578098,1.554741575,1.09120323,2.251248341,0.040036126,DB0082910047899_,3.21797307,0.441309342,NA,10047899,Weight increased,10022891,Investigations,Inv,diazepam,DB00829
,14757,DB00264,10024384,34,29573,31,24861,0.80359796,0.922023559,0.549686878,1.551706855,0.893736666,DB0026410024384_,0.112344104,-0.081184504,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,metoprolol,DB00264
,14759,DB00158,10001053,52,16763,35,8069,0.13606246,0.715149726,0.456681442,1.132147059,0.264204319,DB0015810001053_,1.331032541,-0.335263351,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,14761,DB00421,10001053,98,8805,54,5198,0.735913117,1.071371921,0.759451593,1.525309663,0.84741315,DB0042110001053_,0.165566922,0.068939996,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,14770,DB01220,10001946,45,1249,39,1097,1,1.013421615,0.639931244,1.611036659,1,DB0122010001946_,0,0.013332343,NA,10001946,Ammonia increased,10022891,Investigations,Inv,rifaximin,DB01220
,14775,DB00421,10019660,46,8857,54,5198,0.000573741,0.499949493,0.329384325,0.756099698,0.003461277,DB0042110019660_,5.666117643,-0.6932482,NA,10019660,Hepatic encephalopathy,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,14777,DB01220,10019660,61,1233,71,1065,0.106337035,0.742189365,0.51301593,1.071147097,0.220692379,DB0122010019660_,1.510985499,-0.29815086,NA,10019660,Hepatic encephalopathy,10029205,Nervous system disorders,Nerv,rifaximin,DB01220
,14780,DB00158,10021143,66,16749,41,8063,0.214660347,0.774975243,0.516522216,1.174967589,0.367069128,DB0015810021143_,1.002205089,-0.254924195,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,14782,DB00421,10021143,152,8751,58,5194,0.003933683,1.555417356,1.139821092,2.147261063,0.016846737,DB0042110021143_,4.083598314,0.441743906,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,14787,DB00158,10046571,449,16366,95,8009,1.9123777655116e-15,2.312841482,1.846569543,2.921857965,1.24115677941907e-13,DB0015810046571_,29.71756238,0.838476847,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,folic acid,DB00158
,14788,DB00165,10046571,49,2096,19,1347,0.077864569,1.657142606,0.953124371,2.994528734,0.174749846,DB0016510046571_,1.744399782,0.505094797,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,pyridoxine,DB00165
,14789,DB00421,10046571,203,8700,64,5188,4.91270923727159e-06,1.891378118,1.418286416,2.551446213,5.82324970920784e-05,DB0042110046571_,9.75106699,0.637305726,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,spironolactone,DB00421
,14790,DB00811,10046571,37,2761,22,4134,0.000710207,2.517829525,1.443176065,4.491105531,0.004143793,DB0081110046571_,5.486143806,0.923397231,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ribavirin,DB00811
,14792,DB08934,10046571,48,4441,16,6188,1.30272574198554e-07,4.179599474,2.328285169,7.896663099,2.31080882852283e-06,DB0893410046571_,12.97791295,1.430215422,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,sofosbuvir,DB08934
,14816,DB08877,10013709,84,3205,59,3170,0.051506324,1.408101552,0.993545253,2.006645107,0.12782964,DB0887710013709_,2.057056841,0.34224238,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,14818,DB00158,10001760,235,16580,29,8075,3.0189957800473e-16,3.946156558,2.673597384,6.028274904,2.14181657431966e-14,DB0015810001760_,31.47453697,1.372742082,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,14819,DB00641,10001760,184,13940,37,12438,3.53026880913596e-21,4.436818011,3.10034216,6.505237601,4.17987007424048e-19,DB0064110001760_,42.3188366,1.489937455,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,14820,DB01136,10001760,111,9773,21,11094,1.04550512957685e-18,5.999411046,3.736174924,10.08176727,9.64249204593947e-17,DB0113610001760_,36.87776699,1.791661305,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,carvedilol,DB01136
,14821,DB08877,10001760,51,3238,12,3217,7.07481637241774e-07,4.221358871,2.215163583,8.715977003,1.05480715886813e-05,DB0887710001760_,11.4595675,1.440157084,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,ruxolitinib,DB08877
,14822,DB14500,10001760,93,7716,9,4064,2.86948308293142e-09,5.442656459,2.742699686,12.28643005,7.28034390297804e-08,DB1450010001760_,16.43550264,1.694267261,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,potassium,DB14500
,14825,DB00073,10008479,84,7322,67,6340,0.623813022,1.085611511,0.776647762,1.52248344,0.763766695,DB0007310008479_,0.26949291,0.082143433,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,14826,DB00073,10021097,102,7304,159,6248,2.27248700615019e-06,0.548791656,0.422694389,0.709839731,2.96438317402768e-05,DB0007310021097_,10.42625649,-0.600036407,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,rituximab,DB00073
,14830,DB00112,10008479,80,5853,51,4040,0.720618967,1.082743943,0.750819722,1.573735169,0.83523545,DB0011210008479_,0.180041618,0.079498507,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,14831,DB00448,10008479,80,5065,37,3087,0.179461758,1.317745185,0.879407584,2.007254218,0.323225358,DB0044810008479_,1.129405497,0.275922082,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,14832,DB00572,10008479,51,2851,45,2081,0.404150056,0.827277766,0.540794412,1.269236283,0.573848542,DB0057210008479_,0.555389781,-0.189614769,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,atropine,DB00572
,14833,DB01076,10008479,410,25337,395,25188,0.669977623,1.031877425,0.895468823,1.18918056,0.799758272,DB0107610008479_,0.223445757,0.031379886,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,14837,DB00112,10012735,376,5557,254,3837,0.801816517,1.022127981,0.864637799,1.209777036,0.892794236,DB0011210012735_,0.113399143,0.02188671,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,14838,DB00448,10012735,281,4864,125,2999,0.002753764,1.385997656,1.112947162,1.733863961,0.012602537,DB0044810012735_,4.373857099,0.32642021,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lansoprazole,DB00448
,14839,DB00526,10012735,144,1454,158,1736,0.506413435,1.088127966,0.852671547,1.387851508,0.66720519,DB0052610012735_,0.404657649,0.084458757,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,oxaliplatin,DB00526
,14840,DB00544,10012735,244,2191,232,2421,0.123163061,1.162092451,0.957825739,1.410189966,0.245905133,DB0054410012735_,1.402809458,0.150222217,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fluorouracil,DB00544
,14841,DB00572,10012735,428,2474,294,1832,0.370645628,1.078019543,0.915738254,1.270198792,0.540357802,DB0057210012735_,0.615523763,0.075125602,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,atropine,DB00572
,14842,DB00813,10012735,390,10182,177,9991,3.56225874165923e-18,2.161969367,1.801398916,2.602785079,3.11076315696056e-16,DB0081310012735_,35.7064934,0.77101955,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,14844,DB06626,10012735,117,571,223,1229,0.342487098,1.129195775,0.875699637,1.451011309,0.511798139,DB0662610012735_,0.669824991,0.121505676,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,axitinib,DB06626
,14846,DB00112,10020772,370,5563,144,3947,7.26899280914584e-10,1.822930941,1.49291179,2.235435818,2.07341807909277e-08,DB0011210020772_,17.69148225,0.600445613,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,bevacizumab,DB00112
,14847,DB00448,10020772,76,5069,41,3083,0.565799627,1.127415057,0.759118865,1.69559243,0.71730119,DB0044810020772_,0.332259457,0.119927452,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,lansoprazole,DB00448
,14848,DB00526,10020772,36,1562,35,1859,0.402600709,1.224069185,0.743100732,2.018196365,0.572378805,DB0052610020772_,0.55795426,0.202180706,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,oxaliplatin,DB00526
,14849,DB00544,10020772,39,2396,42,2611,1,1.011893825,0.634886886,1.609367813,1,DB0054410020772_,0,0.011823649,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,fluorouracil,DB00544
,14850,DB00572,10020772,42,2860,28,2098,0.71680637,1.100356241,0.663724154,1.849726876,0.83256028,DB0057210020772_,0.183249651,0.095633983,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,atropine,DB00572
,14851,DB01076,10020772,357,25390,301,25282,0.037491058,1.18099632,1.00919057,1.382821427,0.100576899,DB0107610020772_,2.29683268,0.166358422,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,atorvastatin,DB01076
,14853,DB06626,10020772,58,630,91,1361,0.069354246,1.37673176,0.959398617,1.962834185,0.160163095,DB0662610020772_,1.831562637,0.319712401,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,axitinib,DB06626
,14856,DB00381,10040741,42,29318,41,22846,0.320247159,0.79826238,0.506408748,1.259147552,0.488484721,DB0038110040741_,0.716447086,-0.225317938,NA,10040741,Sinus bradycardia,10007541,Cardiac disorders,Card,amlodipine,DB00381
,14869,DB06643,10000060,119,52302,11,7504,0.184839147,1.552121693,0.836333978,3.194820356,0.329960065,DB0664310000060_,1.108783647,0.439622829,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,14874,DB06643,10033371,1323,51098,127,7388,5.44589833390898e-06,1.506176933,1.252441561,1.8245413,6.37051347159758e-05,DB0664310033371_,9.661245391,0.409574608,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,14890,DB00437,10037884,45,6876,47,11499,0.030218184,1.601065511,1.038671237,2.465584698,0.085164312,DB0043710037884_,2.463172805,0.470669352,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,14891,DB00497,10037884,46,19221,41,16334,0.830324844,0.953412732,0.611809162,1.490379063,0.911010917,DB0049710037884_,0.093200398,-0.047707382,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,14895,DB00736,10011906,259,10332,236,5317,8.1401161018666e-10,0.564765691,0.47011972,0.678766906,2.30439366437871e-08,DB0073610011906_,17.58586315,-0.57134434,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,14896,DB13961,10011906,155,9302,272,6142,9.23831245373051e-23,0.376289575,0.306100173,0.461266198,1.23263473526044e-20,DB1396110011906_,45.84254792,-0.977396285,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,14902,DB00005,10047943,125,127957,58,42361,0.039618167,0.713485646,0.51844461,0.991948142,0.10489157,DB0000510047943_,2.254828129,-0.33759296,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,etanercept,DB00005
,14904,DB00646,10002034,113,3340,57,1943,0.419217739,1.153267652,0.827121605,1.622974329,0.588283502,DB0064610002034_,0.530546301,0.14259935,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,nystatin,DB00646
,14906,DB00688,10002034,120,6370,79,5299,0.114350931,1.263571215,0.941004396,1.704633672,0.232658427,DB0068810002034_,1.458183881,0.23394201,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,mycophenolate mofetil,DB00688
,14907,DB00927,10002034,166,7331,88,4928,0.080627538,1.268015843,0.970824376,1.665595386,0.179422127,DB0092710002034_,1.718013996,0.23745335,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,famotidine,DB00927
,14908,DB01306,10002034,74,4134,79,3787,0.369268669,0.858100802,0.614401608,1.197404836,0.538935423,DB0130610002034_,0.618159523,-0.153033701,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,insulin aspart,DB01306
,14909,DB01307,10002034,33,2491,31,2038,0.614094402,0.870956665,0.515123143,1.475976567,0.755669793,DB0130710002034_,0.28015078,-0.138163056,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,insulin detemir,DB01307
,14910,DB01610,10002034,28,913,35,1183,0.89806096,1.036583361,0.602575544,1.768391072,0.956338178,DB0161010002034_,0.044643686,0.035930075,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,valganciclovir,DB01610
,14912,DB00211,10031127,21,1415,63,1568,5.09731437436703e-05,0.369510747,0.212952274,0.6176015,0.000449456,DB0021110031127_,7.707472038,-0.995575454,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,midodrine,DB00211
,14914,DB00687,10031127,20,966,43,1042,0.010450539,0.5018711,0.277583161,0.879028838,0.036864043,DB0068710031127_,3.300518651,-0.689411965,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,fludrocortisone,DB00687
,14918,DB01076,10031127,26,25721,60,25523,0.000212376,0.429980751,0.260373459,0.692182444,0.001514463,DB0107610031127_,6.492694157,-0.844014837,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,atorvastatin,DB01076
,14936,DB00997,10011906,290,5041,127,3387,6.1744285207753e-05,1.534165659,1.235227643,1.914019319,0.000528427,DB0099710011906_,7.545606442,0.427986688,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,14937,DB00997,10013950,32,5299,32,3482,0.096672147,0.657155739,0.38900421,1.110077812,0.205767867,DB0099710013950_,1.581006607,-0.419834243,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,doxorubicin,DB00997
,14941,DB00115,10000087,265,18160,100,10372,0.000357111,1.513514396,1.196480978,1.92709863,0.002332008,DB0011510000087_,6.061025756,0.414434361,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,14943,DB00335,10000087,115,8351,42,5423,0.001276365,1.778001744,1.236414949,2.600178378,0.006723298,DB0033510000087_,5.002176528,0.575490118,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,14944,DB00381,10000087,378,28982,196,22691,2.4913902827619e-06,1.509930326,1.266165998,1.805155306,3.20932093028163e-05,DB0038110000087_,10.3468661,0.412063508,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,14945,DB00451,10000087,698,46573,156,15263,1.03093805518619e-05,1.466302605,1.229710595,1.757435559,0.000111469,DB0045110000087_,9.101760605,0.382743998,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,14946,DB05676,10000087,1203,45926,639,24690,0.823756233,1.012108929,0.917575047,1.11716802,0.906573661,DB0567610000087_,0.098082993,0.012036202,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,14947,DB14513,10000087,106,7071,23,3541,0.00014506,2.307779877,1.456625824,3.804281493,0.00109598,DB1451310000087_,6.816106658,0.83628597,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,14950,DB00169,10011469,96,38595,12,18163,7.15093933084146e-07,3.76440992,2.058187011,7.541975119,1.06464140646371e-05,DB0016910011469_,11.45028743,1.325591121,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,14953,DB00381,10011469,44,29316,7,22880,6.37039145042091e-06,4.905603719,2.191526553,12.91219924,7.3168337021767e-05,DB0038110011469_,9.522747785,1.590378168,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,14954,DB00563,10011469,43,46603,7,15341,0.099495597,2.021999131,0.901618194,5.329383205,0.210099692,DB0056310011469_,1.560173137,0.704086691,NA,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,14955,DB05676,10011469,85,47044,7,25322,1.76689834889309e-09,6.536449266,3.037352807,16.74710496,4.66763046237739e-08,DB0567610011469_,16.8800292,1.877394092,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,14957,DB00115,10012374,62,18363,11,10461,7.83896102747284e-05,3.210801495,1.675337448,6.765478804,0.000647438,DB0011510012374_,7.342487779,1.166520593,female,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,14958,DB00158,10012374,57,16758,17,8087,0.082723127,1.618018608,0.927150756,2.969127266,0.182928312,DB0015810012374_,1.698660941,0.481202319,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,folic acid,DB00158
,14959,DB00169,10012374,127,38564,41,18134,0.038069576,1.456567885,1.016520335,2.126107893,0.101745475,DB0016910012374_,2.285280927,0.376082904,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,14962,DB00381,10012374,63,29297,20,22867,0.000228483,2.458566453,1.466175212,4.29498334,0.00161118,DB0038110012374_,6.430788361,0.899578437,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,14963,DB00451,10012374,129,47142,31,15388,0.141121563,1.358296615,0.911466863,2.081720536,0.271455213,DB0045110012374_,1.303958113,0.306231426,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,14964,DB00563,10012374,76,46570,17,15331,0.185125998,1.47169227,0.861220624,2.657817309,0.330315098,DB0056310012374_,1.107708238,0.386412943,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,14965,DB05676,10012374,129,47000,74,25255,0.658758767,0.93671676,0.698168183,1.264655362,0.791600722,DB0567610012374_,0.233698153,-0.065374326,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,14967,DB00158,10012378,299,16516,78,8026,3.95909582883996e-07,1.862778158,1.445217211,2.425330045,6.26678902430846e-06,DB0015810012378_,11.98024645,0.622069007,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,folic acid,DB00158
,14968,DB00227,10012378,31,2436,26,1777,0.592902998,0.869788997,0.497795905,1.531029352,0.739072644,DB0022710012378_,0.302359063,-0.139504629,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,lovastatin,DB00227
,14969,DB00335,10012378,132,8334,54,5411,0.003998006,1.587048443,1.145707706,2.224773917,0.017072143,DB0033510012378_,4.070307182,0.461875966,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,atenolol,DB00335
,14970,DB00381,10012378,343,29017,147,22740,3.81832053839489e-10,1.828548248,1.501785131,2.23556668,1.14440770070364e-08,DB0038110012378_,18.28579353,0.603522345,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,14971,DB00227,10013709,118,2349,86,1717,1,1.002929836,0.747644968,1.349810177,1,DB0022710013709_,0,0.002925552,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lovastatin,DB00227
,14972,DB05676,10013709,3808,43321,2569,22760,2.25910332291064e-20,0.778787613,0.738647016,0.821100518,2.41875889379658e-18,DB0567610013709_,40.56327712,-0.250016911,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,14973,DB14513,10013709,311,6866,144,3420,0.508465745,1.075770691,0.87617487,1.325746501,0.668983661,DB1451310013709_,0.401995642,0.073037326,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,14974,DB00273,10019211,536,7945,84,2109,4.76096727338442e-06,1.693690076,1.336262498,2.168955269,5.66509845092392e-05,DB0027310019211_,9.778601192,0.526909626,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,14976,DB06724,10016173,332,7597,122,3797,0.004341742,1.360084845,1.097726274,1.694085776,0.018250869,DB0672410016173_,4.003542595,0.307547084,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium carbonate,DB06724
,14977,DB00115,10016454,62,18363,15,10457,0.001862227,2.353705622,1.322416676,4.457426354,0.009176721,DB0011510016454_,4.691085343,0.855990947,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,14978,DB06724,10016454,91,7838,20,3899,0.000514232,2.263256903,1.380962579,3.884557332,0.00315882,DB0672410016454_,5.757556881,0.816804883,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium carbonate,DB06724
,14981,DB01065,10013573,147,4184,84,2967,0.135180135,1.240941355,0.938618388,1.649529572,0.262928064,DB0106510013573_,1.335874806,0.215870249,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,melatonin,DB01065
,14988,DB00285,10022523,119,10832,48,3670,0.324966922,0.840009522,0.594657765,1.202907673,0.493429354,DB0028510022523_,0.706375583,-0.174342051,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,14992,DB01065,10028813,302,4029,112,2939,5.65150716661211e-10,1.966751739,1.569541636,2.478594873,1.64234235350359e-08,DB0106510028813_,17.92455726,0.676383318,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,melatonin,DB01065
,15000,DB00555,10040752,44,7003,19,3467,0.688224673,1.146462224,0.65442502,2.082596133,0.812014935,DB0055510040752_,0.208236546,0.136680874,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,lamotrigine,DB00555
,15002,DB00285,10042464,122,10829,44,3674,0.720127687,0.940713652,0.6599296,1.362778179,0.834794868,DB0028510042464_,0.180569251,-0.061116488,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,15003,DB00555,10042464,65,6982,55,3431,0.004435113,0.580769315,0.398297098,0.849521095,0.018555823,DB0055510042464_,3.986971654,-0.543401649,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,15007,DB00051,10022107,177,25554,26,11394,2.61862637731939e-09,3.035240192,2.002442251,4.778187606,6.70210266093868e-08,DB0005110022107_,16.51825944,1.110290562,female,10022107,Injection site urticaria,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,15008,DB00051,10003658,49,25682,37,11383,0.018641863,0.586987487,0.375025399,0.925845108,0.058461743,DB0005110003658_,2.839382699,-0.532751776,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,adalimumab,DB00051
,15009,DB00524,10003658,71,1506,49,1295,0.262463456,1.245874153,0.846696254,1.845922231,0.4242445,DB0052410003658_,0.857445339,0.219837414,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,metolazone,DB00524
,15010,DB00051,10008479,203,25528,100,11320,0.382368198,0.900179849,0.704297763,1.15674417,0.552455576,DB0005110008479_,0.593382253,-0.105160704,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,15011,DB00524,10008479,82,1495,30,1314,2.67521607760808e-05,2.401615071,1.551873102,3.806907758,0.000256121,DB0052410008479_,8.269860085,0.876141457,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,15012,DB00051,10010305,76,25655,33,11387,1,1.022216062,0.67052769,1.589323154,1,DB0005110010305_,0,0.02197288,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,adalimumab,DB00051
,15014,DB00524,10016256,129,1448,76,1268,0.008771033,1.486166191,1.099057217,2.020788966,0.03205598,DB0052410016256_,3.440271539,0.396199778,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,15015,DB00051,10021097,72,25659,34,11386,0.752724734,0.939693742,0.616341815,1.458470151,0.860733565,DB0005110021097_,0.149970271,-0.062201263,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,adalimumab,DB00051
,15016,DB00524,10021097,113,1464,108,1236,0.399792563,0.883387271,0.664993993,1.174007877,0.569668054,DB0052410021097_,0.56270145,-0.123991589,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,metolazone,DB00524
,15019,DB00559,10002855,105,9554,18,3288,0.004776513,2.007537918,1.20801105,3.523690756,0.019722146,DB0055910002855_,3.926013125,0.696909055,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,bosentan,DB00559
,15020,DB00682,10002855,260,19199,102,16262,1.00923231759915e-11,2.158981022,1.709004262,2.744700146,3.85576620175778e-10,DB0068210002855_,21.67628119,0.769636361,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,15021,DB01240,10002855,145,5606,32,1544,0.308048582,1.247952685,0.842277701,1.899984238,0.475263074,DB0124010002855_,0.743886789,0.221504357,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,epoprostenol,DB01240
,15022,DB00559,10012587,56,9603,8,3298,0.014330109,2.404067704,1.138247095,5.845982753,0.04748401,DB0055910012587_,3.047362262,0.877162179,NA,10012587,Device leakage,10077536,Product issues,Prod,bosentan,DB00559
,15023,DB00682,10012587,130,19329,18,16346,2.42716212849585e-18,6.107359937,3.713783008,10.63638276,2.15170173853334e-16,DB0068210012587_,36.07510245,1.809494591,female,10012587,Device leakage,10077536,Product issues,Prod,warfarin,DB00682
,15024,DB01240,10012587,252,5499,54,1522,0.101927893,1.291577137,0.953528639,1.776457943,0.213863473,DB0124010012587_,1.542417443,0.255864059,NA,10012587,Device leakage,10077536,Product issues,Prod,epoprostenol,DB01240
,15025,DB01240,10064911,539,5212,144,1432,0.806934677,1.028417008,0.845866318,1.256282155,0.895666483,DB0124010064911_,0.110187164,0.028020734,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,15026,DB00355,10011906,156,1637,118,1145,0.562998815,0.924721347,0.714475377,1.199217189,0.715096999,DB0035510011906_,0.335337083,-0.078262834,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,aztreonam,DB00355
,15027,DB00203,10038695,338,13540,165,8773,0.00308861,1.32726242,1.096368854,1.61179923,0.013852763,DB0020310038695_,4.279270604,0.28311849,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,15028,DB08932,10038695,431,19012,186,6411,0.006533036,0.78138643,0.654828035,0.935253397,0.02534251,DB0893210038695_,3.675272054,-0.246685463,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,15029,DB00203,10061818,265,13613,109,8829,5.83938739983454e-05,1.576770209,1.254772011,1.992658102,0.000504224,DB0020310061818_,7.592490216,0.455378583,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,15030,DB08932,10064911,1095,18348,329,6268,0.048332135,1.136986018,1.000806758,1.294356255,0.121937914,DB0893210064911_,2.104243263,0.128380917,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,15031,DB00005,10022079,293,127789,58,42361,0.000198263,1.674535569,1.259501117,2.260206798,0.001430315,DB0000510022079_,6.549860875,0.515535855,NA,10022079,Injection site irritation,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,15039,DB00958,10011906,435,4159,270,2315,0.18628392,0.896799948,0.762059087,1.056723414,0.331784309,DB0095810011906_,1.103270193,-0.108922466,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,15040,DB00958,10051398,121,4473,100,2485,0.004340647,0.672230703,0.509101254,0.88931939,0.018247726,DB0095810051398_,4.003714814,-0.397153689,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,carboplatin,DB00958
,15043,DB00958,10028813,494,4100,156,2429,7.54073148882447e-12,1.875898873,1.552387745,2.276465012,2.93859343489624e-10,DB0095810028813_,21.94791989,0.629087944,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,carboplatin,DB00958
,15044,DB00958,10029354,227,4367,125,2460,0.864528169,1.022979175,0.813988419,1.290316423,0.937889427,DB0095810029354_,0.064123219,0.02271913,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,carboplatin,DB00958
,15045,DB00958,10047700,332,4262,124,2461,4.25734607569836e-05,1.545928692,1.246217424,1.927404935,0.00038508,DB0095810047700_,7.862058617,0.435624825,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,carboplatin,DB00958
,15046,DB00153,10040753,187,7236,32,3407,6.73748078151759e-09,2.751263859,1.878755459,4.147918779,1.56986639554243e-07,DB0015310040753_,15.66710513,1.012060391,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,ergocalciferol,DB00153
,15047,DB00316,10040753,1283,64191,345,36608,2.44783195215409e-39,2.120829833,1.880242798,2.397252131,9.39288508939712e-37,DB0031610040753_,82.95569594,0.751807443,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,15049,DB00476,10040753,270,16987,33,6144,2.90325747658727e-11,2.959374933,2.054055396,4.392141098,1.03194216054221e-09,DB0047610040753_,20.69182322,1.084978075,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,duloxetine,DB00476
,15050,DB00874,10040753,159,3176,45,1931,2.76732147807519e-06,2.147975569,1.525871077,3.076185812,3.52825183403789e-05,DB0087410040753_,10.25212295,0.764525803,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,guaifenesin,DB00874
,15051,DB00656,10036661,6,12007,121,6498,7.99904018926194e-47,0.026839389,0.009664454,0.060181477,4.23080438392366e-44,DB0065610036661_,99.87135196,-3.617884746,male,10036661,Priapism,10038604,Reproductive system and breast disorders,Repro,trazodone,DB00656
,15053,DB00722,10070863,376,25027,452,25580,0.022703182,0.850242804,0.738689714,0.978180137,0.068215951,DB0072210070863_,2.685076857,-0.162233318,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,15055,DB00005,10037888,74,128008,25,42394,0.907764277,0.980299355,0.615443687,1.610735088,0.958771936,DB0000510037888_,0.042102046,-0.019897289,NA,10037888,Rash pustular,10021881,Infections and infestations,Infec,etanercept,DB00005
,15056,DB00404,10013663,74,19818,63,9799,0.001887711,0.580776985,0.409024105,0.826826009,0.009283151,DB0040410013663_,4.679554287,-0.543388443,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,15057,DB00404,10027940,37,19855,14,9848,0.45772853,1.310877935,0.69177218,2.626189079,0.625023736,DB0040410027940_,0.469965653,0.270697092,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,15058,DB06605,10011906,1240,12833,1321,11712,0.000198834,0.856692527,0.788998587,0.930154226,0.001433249,DB0660510011906_,6.547811046,-0.154676203,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,15059,DB00008,10002855,31,1494,29,1647,0.602160101,1.178375344,0.683403901,2.037264657,0.746241313,DB0000810002855_,0.292706255,0.164136663,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,peginterferon alfa-2a,DB00008
,15066,DB00008,10012378,70,1455,82,1594,0.739433811,0.935206268,0.664407314,1.313558583,0.85016024,DB0000810012378_,0.16233043,-0.066988167,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,peginterferon alfa-2a,DB00008
,15089,DB00008,10037660,67,1458,64,1612,0.422732593,1.157395709,0.803015019,1.669410671,0.591668062,DB0000810037660_,0.524809507,0.146172403,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,peginterferon alfa-2a,DB00008
,15090,DB00811,10037660,84,2714,90,4066,0.034241451,1.398182606,1.021795649,1.911722267,0.093885832,DB0081110037660_,2.36567579,0.335173255,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,15096,DB00811,10037884,32,2766,33,4123,0.16178062,1.445319003,0.858263304,2.431151041,0.299771147,DB0081110037884_,1.204735939,0.368330061,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,ribavirin,DB00811
,15120,DB01240,10019211,1347,4404,310,1266,0.001567769,1.249002133,1.085957153,1.439384233,0.007969191,DB0124010019211_,4.832172236,0.222344939,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,epoprostenol,DB01240
,15121,DB00331,10001949,95,24851,43,20709,0.000785017,1.841025275,1.270683692,2.706001965,0.004503801,DB0033110001949_,5.40283366,0.610322631,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,metformin,DB00331
,15126,DB05259,10022093,433,10837,73,2655,0.002915282,1.453133958,1.12724959,1.895563542,0.013196969,DB0525910022093_,4.32776811,0.373722574,NA,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,15127,DB00982,10027940,119,3245,141,1960,1.40828284154531e-07,0.509818246,0.393446055,0.659795615,2.47769173293297e-06,DB0098210027940_,12.90818318,-0.673700996,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,isotretinoin,DB00982
,15130,DB00813,10000087,71,10501,37,10131,0.002612505,1.851243389,1.226050394,2.836868397,0.012078041,DB0081310000087_,4.416366245,0.615857515,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,15131,DB01261,10000087,82,3699,48,3255,0.026495153,1.503188655,1.036629806,2.200628912,0.076842667,DB0126110000087_,2.565995239,0.407588622,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,sitagliptin,DB01261
,15132,DB00413,10012735,99,2100,40,1167,0.103159992,1.375269993,0.936315062,2.053168532,0.215733979,DB0041310012735_,1.533709209,0.31865007,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pramipexole,DB00413
,15133,DB01261,10012735,221,3560,152,3151,0.021753137,1.286858939,1.035978764,1.601806045,0.066056055,DB0126110012735_,2.717251585,0.252204318,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sitagliptin,DB01261
,15145,DB00682,10008479,648,18811,251,16113,2.54233466462866e-28,2.211273771,1.905529472,2.572525335,5.00563795204228e-26,DB0068210008479_,58.25664755,0.793568716,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,15146,DB01240,10008479,480,5271,80,1496,8.30016782051669e-06,1.702870561,1.331335836,2.200760974,9.23861575957151e-05,DB0124010008479_,9.2895334,0.532315392,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,15147,DB00682,10012575,80,19379,12,16352,2.93072648909115e-11,5.625077379,3.047676327,11.34497086,1.04100196980758e-09,DB0068210012575_,20.68308216,1.727234704,female,10012575,Device breakage,10077536,Product issues,Prod,warfarin,DB00682
,15148,DB01240,10012575,152,5599,27,1549,0.034023813,1.557361167,1.024741008,2.450057381,0.09344994,DB0124010012575_,2.370329392,0.442992829,NA,10012575,Device breakage,10077536,Product issues,Prod,epoprostenol,DB01240
,15149,DB00682,10057362,36,19423,33,16331,0.71877623,0.917246937,0.555613399,1.518759121,0.833911611,DB0068210057362_,0.181627864,-0.086378555,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,15154,DB00635,10036495,40,33013,11,23783,0.002754354,2.619616016,1.318874282,5.661881052,0.012603044,DB0063510036495_,4.373816943,0.963027748,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,15157,DB00203,10053762,360,13518,286,8652,0.007833535,0.805655525,0.686192029,0.946571371,0.029278986,DB0020310053762_,3.530885205,-0.216099016,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,15158,DB01611,10053762,489,11424,199,2162,9.09741755335599e-17,0.465071797,0.391000094,0.554767164,6.7933414883512e-15,DB0161110053762_,32.62283346,-0.765563483,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxychloroquine,DB01611
,15197,DB00388,10047513,32,604,29,521,0.895496063,0.951830961,0.549538557,1.6548937,0.95615204,DB0038810047513_,0.044838341,-0.049367822,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,phenylephrine,DB00388
,15198,DB00465,10047513,41,2063,13,870,0.452370922,1.32986275,0.694382889,2.719136184,0.619978606,DB0046510047513_,0.478070308,0.285075741,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ketorolac,DB00465
,15199,DB00586,10047513,77,7032,20,2785,0.112013672,1.52477251,0.920551893,2.63875561,0.229100057,DB0058610047513_,1.473596441,0.421845225,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,diclofenac,DB00586
,15204,DB15566,10047513,61,946,26,636,0.056465324,1.576919302,0.969256662,2.630416083,0.13689905,DB1556610047513_,1.988511489,0.455473135,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,prednisolone acetate,DB15566
,15205,DB00388,10047531,32,604,23,527,0.580106649,1.21373808,0.678745903,2.201744045,0.72869727,DB0038810047531_,0.316496901,0.19370492,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,phenylephrine,DB00388
,15212,DB15566,10047531,35,972,20,642,0.675374763,1.155729143,0.642414535,2.133132804,0.80322693,DB1556610047531_,0.219118002,0.144731438,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,prednisolone acetate,DB15566
,15229,DB00177,10013573,221,4579,108,2742,0.091242462,1.225303832,0.96410701,1.564835615,0.197237395,DB0017710013573_,1.623347225,0.20318884,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,valsartan,DB00177
,15230,DB01611,10003549,208,11705,37,2324,0.602925132,1.116136207,0.781316614,1.63412938,0.746678937,DB0161110003549_,0.292119989,0.109872906,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,15231,DB00635,10012378,466,32587,177,23617,3.77278485531743e-14,1.908032394,1.600112664,2.283461386,2.04469381282513e-12,DB0063510012378_,26.91577306,0.646072551,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,15232,DB01611,10012378,152,11761,27,2334,0.685488524,1.117188801,0.736333946,1.754946504,0.810091981,DB0161110012378_,0.21060748,0.11081553,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,hydroxychloroquine,DB01611
,15233,DB00451,10013786,317,46954,99,15320,0.732111532,1.044773309,0.830533162,1.323814948,0.844367242,DB0045110013786_,0.169167758,0.043799932,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,15234,DB00635,10013786,130,32923,52,23742,0.000280369,1.802817776,1.296917004,2.538252535,0.001910931,DB0063510013786_,6.260164761,0.589350872,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,15235,DB01611,10013786,55,11858,8,2353,0.498371199,1.364187053,0.644938347,3.320949527,0.660264011,DB0161110013786_,0.415115508,0.310558686,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxychloroquine,DB01611
,15236,DB00635,10016173,755,32298,397,23397,2.36640690396441e-07,1.377647721,1.216918297,1.561409379,3.94801684993364e-06,DB0063510016173_,12.44229717,0.320377495,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,15237,DB01611,10016173,225,11688,32,2329,0.075539682,1.401042979,0.961584916,2.103337893,0.170705459,DB0161110016173_,1.767815669,0.337216945,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxychloroquine,DB01611
,15238,DB00635,10016256,1882,31171,1207,22587,0.001255879,1.129815152,1.048374465,1.218014251,0.006634664,DB0063510016256_,5.015447316,0.122054037,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,15239,DB01611,10016256,614,11299,88,2273,0.00294904,1.403568521,1.1154793,1.783618605,0.013314242,DB0161110016256_,4.31892099,0.339017937,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,15240,DB00451,10029216,184,47087,30,15389,0.000173794,2.004366223,1.356795257,3.056906285,0.001281037,DB0045110029216_,6.660085271,0.695327912,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,15241,DB00635,10029216,79,32974,19,23775,2.90144808233467e-06,2.997838462,1.798634152,5.241668713,3.68333858785523e-05,DB0063510029216_,10.2091059,1.097891516,female,10029216,Nervousness,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,15243,DB00451,10047340,223,47048,40,15379,0.000240742,1.822248328,1.296259852,2.62106813,0.001681167,DB0045110047340_,6.388267132,0.600071084,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,levothyroxine,DB00451
,15244,DB00635,10047340,95,32958,29,23765,2.24318092805137e-05,2.362068044,1.543649931,3.715662605,0.000220378,DB0063510047340_,8.420168394,0.859537525,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,prednisone,DB00635
,15249,DB00635,10061428,426,32627,372,23422,0.006693984,0.822086586,0.712926771,0.94830031,0.025854289,DB0063510061428_,3.655278775,-0.195909554,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,15251,DB00425,10028735,66,12629,41,7443,0.841051695,0.948728109,0.632237665,1.438657609,0.918820335,DB0042510028735_,0.084664676,-0.052633024,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,15252,DB00559,10028735,163,9496,36,3270,0.017146108,1.559054796,1.078557578,2.308700402,0.054751315,DB0055910028735_,2.904953883,0.444079737,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,15253,DB00682,10028735,379,19080,109,16255,4.66808348353537e-27,2.962003781,2.385103805,3.703807037,8.34697784794062e-25,DB0068210028735_,55.44272779,1.085865993,female,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,15254,DB01240,10028735,180,5571,34,1542,0.042655851,1.465270553,1.006277015,2.190740263,0.111028537,DB0124010028735_,2.197968018,0.382039903,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,15256,DB00455,10060795,48,9353,25,5093,0.902829269,1.045499192,0.631112379,1.77178289,0.957326661,DB0045510060795_,0.043610607,0.044494467,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,loratadine,DB00455
,15257,DB00471,10060795,58,14131,11,5454,0.030401784,2.035011487,1.056562981,4.303345485,0.08554999,DB0047110060795_,2.458654395,0.710501463,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,montelukast,DB00471
,15258,DB00863,10060795,48,10625,29,5811,0.72027489,0.905250948,0.558671619,1.490502952,0.83489187,DB0086310060795_,0.180453059,-0.099543084,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,ranitidine,DB00863
,15272,DB15566,10015946,49,958,13,649,0.00211784,2.552201146,1.350148001,5.170527248,0.010195501,DB1556610015946_,4.585808775,0.936956181,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,prednisolone acetate,DB15566
,15274,DB00281,10015958,36,11422,15,5656,0.656102779,1.188413896,0.634022341,2.338413538,0.789690754,DB0028110015958_,0.23611386,0.172619558,NA,10015958,Eye pain,10015919,Eye disorders,Eye,lidocaine,DB00281
,15281,DB15566,10015958,43,964,21,641,0.297648952,1.361295184,0.781756162,2.439080632,0.463558151,DB1556610015958_,0.768823441,0.308436588,NA,10015958,Eye pain,10015919,Eye disorders,Eye,prednisolone acetate,DB15566
,15282,DB00218,10019211,58,1384,19,931,0.006216161,2.052896721,1.195558032,3.675548109,0.024348678,DB0021810019211_,3.71527774,0.719251831,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,moxifloxacin,DB00218
,15283,DB00281,10019211,627,10831,177,5494,1.69937354375304e-12,1.79680394,1.513270724,2.142004986,7.35276273210678e-11,DB0028110019211_,23.3333599,0.586009498,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,15285,DB00465,10019211,133,1971,16,867,3.14748894435469e-08,3.655181694,2.153367599,6.621727526,6.33716942951842e-07,DB0046510019211_,14.27166344,1.296145803,female,10019211,Headache,10029205,Nervous system disorders,Nerv,ketorolac,DB00465
,15286,DB00586,10019211,387,6722,99,2706,5.35801601312718e-05,1.573573381,1.252727667,1.991862851,0.000468125,DB0058610019211_,7.666774887,0.453349072,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,15304,DB00218,10047531,41,1401,23,927,0.605140853,1.179389745,0.686053027,2.073645307,0.748294749,DB0021810047531_,0.289958329,0.16499714,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,moxifloxacin,DB00218
,15305,DB00281,10047531,43,11415,21,5650,1,1.013500995,0.587715594,1.799662706,1,DB0028110047531_,0,0.013410668,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,lidocaine,DB00281
,15311,DB01362,10013968,57,809,30,560,0.261012944,1.314961914,0.818917946,2.148780058,0.422522841,DB0136210013968_,0.861511771,0.273807702,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iohexol,DB01362
,15312,DB01362,10037087,132,734,67,523,0.035935996,1.403476816,1.015097354,1.954167932,0.097414289,DB0136210037087_,2.328782376,0.338952598,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,iohexol,DB01362
,15317,DB00544,10011224,28,2407,34,2619,0.702643286,0.896091083,0.52172013,1.527601231,0.821592063,DB0054410011224_,0.196511281,-0.109713216,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluorouracil,DB00544
,15321,DB00526,10037660,49,1549,92,1802,0.007435324,0.619684822,0.425993123,0.892213315,0.028098267,DB0052610037660_,3.572047365,-0.478544282,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,oxaliplatin,DB00526
,15322,DB00544,10037660,74,2361,128,2525,0.001181992,0.618343117,0.455418253,0.834531066,0.006324409,DB0054410037660_,5.063338718,-0.480711771,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,fluorouracil,DB00544
,15323,DB00650,10037660,75,2056,122,1892,0.000136333,0.565800016,0.415657605,0.766002865,0.001038851,DB0065010037660_,6.86963958,-0.569514592,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,leucovorin,DB00650
,15327,DB00005,10044008,46,128036,7,42412,0.055497794,2.176638461,0.976036279,5.715311098,0.13516419,DB0000510044008_,2.001265014,0.777781696,NA,10044008,Tonsillitis,10021881,Infections and infestations,Infec,etanercept,DB00005
,15328,DB00682,10030095,433,19026,187,16177,1.87537593106226e-15,1.968703493,1.652432663,2.352827419,1.21864663406605e-13,DB0068210030095_,29.73586528,0.677375201,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,15329,DB01240,10047899,230,5521,54,1522,0.338124265,1.174142815,0.864423407,1.618971816,0.507224992,DB0124010047899_,0.678800603,0.160538362,NA,10047899,Weight increased,10022891,Investigations,Inv,epoprostenol,DB01240
,15332,DB00005,10013036,54,128028,9,42410,0.057353052,1.987412956,0.97309574,4.579410478,0.138463816,DB0000510013036_,1.977146247,0.686833771,NA,10013036,Diplopia,10015919,Eye disorders,Eye,etanercept,DB00005
,15335,DB00758,10013573,309,7991,378,9696,0.93773362,0.991877873,0.84812523,1.159278481,0.977623329,DB0075810013573_,0.022630827,-0.008155291,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,15336,DB01611,10013573,299,11614,40,2321,0.017652243,1.493798121,1.06777009,2.139897075,0.056037345,DB0161110013573_,2.881736942,0.401321951,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,hydroxychloroquine,DB01611
,15337,DB00005,10013952,389,127693,67,42352,1.23598445483323e-07,1.925554619,1.482272803,2.535226325,2.2063056974731e-06,DB0000510013952_,13.02419107,0.65521404,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,15338,DB00758,10013952,44,8256,34,10040,0.052286071,1.573697734,0.982131663,2.541447297,0.129313077,DB0075810013952_,2.045518865,0.453428095,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,15340,DB00758,10016173,323,7977,342,9732,0.07419694,1.152218311,0.983657639,1.349428703,0.168518669,DB0075810016173_,1.78070874,0.14168905,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,15347,DB00005,10062016,88,127994,28,42391,0.914733264,1.040923568,0.673451887,1.65498277,0.961865977,DB0000510062016_,0.038880155,0.040108366,NA,10062016,Immunosuppression,10021428,Immune system disorders,Immun,etanercept,DB00005
,15350,DB01611,10022052,113,11800,10,2351,0.009983553,2.251299553,1.177821873,4.830025977,0.035521853,DB0161110022052_,3.337607208,0.811507629,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,15354,DB00005,10062352,285,127797,82,42337,0.276874035,1.151407951,0.897461771,1.49101054,0.440348158,DB0000510062352_,0.820189596,0.140985499,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,15355,DB00471,10016825,113,14076,35,5430,0.270666013,1.245435582,0.844506316,1.87814926,0.43334589,DB0047110016825_,0.836219048,0.219485334,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,montelukast,DB00471
,15356,DB00588,10016825,127,16397,34,8434,0.000428849,1.921249513,1.305692005,2.896840433,0.002715888,DB0058810016825_,5.908636345,0.652975762,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,fluticasone propionate,DB00588
,15357,DB00635,10016825,195,32858,71,23723,3.65527761510784e-07,1.982883035,1.503007816,2.641596314,5.83003471560132e-06,DB0063510016825_,12.0524876,0.684551864,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,prednisone,DB00635
,15358,DB00471,10028735,130,14059,33,5432,0.034690399,1.522102417,1.030506812,2.306440269,0.094829925,DB0047110028735_,2.355670255,0.420092548,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,15359,DB00588,10028735,191,16333,70,8398,0.014973672,1.402941817,1.060093414,1.874747874,0.049244038,DB0058810028735_,3.010966983,0.33857133,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,15360,DB00635,10028735,234,32819,92,23702,3.50734097954676e-07,1.836881926,1.436442409,2.365624728,5.62651557201017e-06,DB0063510028735_,12.08802021,0.608069529,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,15361,DB00471,10039101,127,14062,35,5430,0.078650036,1.401093906,0.955757267,2.102402228,0.176061675,DB0047110039101_,1.736920918,0.337253293,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,15362,DB00588,10039101,129,16395,53,8415,0.182115651,1.249217465,0.899608188,1.756220121,0.326529722,DB0058810039101_,1.119234302,0.222517327,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,15363,DB00635,10039101,227,32826,80,23714,9.82743134788374e-09,2.049814205,1.581103649,2.680630598,2.21728783673068e-07,DB0063510039101_,15.3218109,0.717749157,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,15364,DB00005,10047924,185,127897,34,42385,0.000977739,1.803112163,1.245441978,2.682257532,0.005408296,DB0000510047924_,5.219821193,0.589514151,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,15365,DB00635,10047924,233,32820,98,23696,4.24377119112294e-06,1.716567683,1.349225131,2.197609557,5.11216891652917e-05,DB0063510047924_,9.881301705,0.540326764,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,15374,DB00635,10015916,72,32981,30,23764,0.011726561,1.729265007,1.11455085,2.744222266,0.040416005,DB0063510015916_,3.2085294,0.547696467,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,prednisone,DB00635
,15384,DB00005,10060800,291,127791,32,42387,1.1261049422409e-11,3.016412423,2.089540969,4.492780303,4.26815694402339e-10,DB0000510060800_,21.57466882,1.104068186,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,etanercept,DB00005
,15393,DB00341,10028334,191,11214,54,5014,0.00264166,1.58143874,1.161203392,2.185006724,0.012187106,DB0034110028334_,4.407376748,0.458335028,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,15395,DB00404,10028334,338,19554,123,9739,0.002751099,1.368640697,1.108518758,1.698877022,0.012596921,DB0040410028334_,4.374302866,0.313818056,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,15396,DB00624,10028334,6,556,48,4348,1,0.9775216,0.340285707,2.301953698,1,DB0062410028334_,0,-0.02273489,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,testosterone,DB00624
,15400,DB00404,10028411,244,19648,81,9781,0.001352716,1.499561155,1.160332372,1.955115288,0.0070632,DB0040410028411_,4.952857029,0.405172502,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,15403,DB00341,10060800,67,11338,11,5057,0.000833863,2.716548764,1.423734021,5.705409832,0.004739045,DB0034110060800_,5.351919688,0.999362238,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,cetirizine,DB00341
,15404,DB00404,10060800,101,19791,26,9836,0.002353595,1.930590735,1.243385622,3.098564702,0.011104694,DB0040410060800_,4.500387357,0.657826037,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,alprazolam,DB00404
,15413,DB00028,10028334,110,13348,40,5575,0.528974095,1.148566798,0.791921602,1.695799316,0.686278032,DB0002810028334_,0.376472439,0.138514902,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,human immunoglobulin g,DB00028
,15414,DB00028,10033557,54,13404,6,5609,0.000528937,3.766229291,1.620875968,10.71714759,0.003231776,DB0002810033557_,5.734723545,1.326074313,female,10033557,Palpitations,10007541,Cardiac disorders,Card,human immunoglobulin g,DB00028
,15419,DB00188,10000087,64,7822,40,8788,0.004065462,1.797515572,1.190854319,2.742471807,0.017316587,DB0018810000087_,4.05609045,0.586405473,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,15420,DB00480,10000087,562,66866,316,67346,3.85075172592657e-17,1.791228614,1.557127692,2.063343492,2.99458606852011e-15,DB0048010000087_,33.44197038,0.582901761,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,15421,DB00188,10008190,36,7850,54,8774,0.203727957,0.745152535,0.47418199,1.158512448,0.35352191,DB0018810008190_,1.039809816,-0.294166337,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,15422,DB00480,10008190,589,66839,548,67114,0.210970994,1.079209367,0.958610731,1.215229676,0.362454497,DB0048010008190_,1.014856337,0.076228705,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,15423,DB00480,10012735,5090,62338,2920,64742,3.32635906264556e-141,1.810349035,1.727125844,1.897864619,1.45722246602731e-137,DB0048010012735_,315.0776255,0.593519664,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,15426,DB00188,10025482,143,7743,118,8710,0.014679587,1.36317651,1.058641065,1.758069702,0.048467899,DB0018810025482_,3.026853579,0.309817646,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,15427,DB00188,10033371,130,7756,125,8703,0.230051263,1.166970352,0.904026967,1.506895654,0.386013243,DB0018810033371_,0.951883601,0.154410948,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,15428,DB00188,10035528,152,7734,237,8591,0.001191641,0.712434186,0.575891524,0.879190458,0.0063715,DB0018810035528_,5.055920436,-0.339067742,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,bortezomib,DB00188
,15429,DB00188,10037844,320,7566,302,8526,0.030119348,1.194033213,1.013915957,1.406420987,0.084958638,DB0018810037844_,2.465590752,0.177336831,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,bortezomib,DB00188
,15430,DB00480,10037844,2306,65122,2194,65468,0.071181624,1.056655554,0.995218923,1.12188797,0.163364096,DB0048010037844_,1.81177385,0.055108782,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,15431,DB00188,10047895,160,7726,210,8618,0.127036403,0.849878791,0.685879388,1.051474967,0.251489501,DB0018810047895_,1.380354035,-0.162661539,NA,10047895,Weight decreased,10022891,Investigations,Inv,bortezomib,DB00188
,15432,DB00480,10047895,1030,66398,1089,66573,0.228519899,0.948296448,0.869404641,1.034294514,0.3840689,DB0048010047895_,0.956933316,-0.053088117,NA,10047895,Weight decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,15437,DB00005,10018276,56,128026,8,42411,0.0202752,2.318708396,1.099395202,5.633467511,0.062470243,DB0000510018276_,2.773064946,0.841010305,NA,10018276,Gingival bleeding,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,15438,DB08935,10029366,22,510,36,777,0.891041055,0.93108368,0.515365206,1.647758195,0.954769945,DB0893510029366_,0.046284862,-0.071406124,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,obinutuzumab,DB08935
,15439,DB08935,10051792,48,484,72,741,0.922331875,1.020653938,0.680447544,1.520014327,0.965799273,DB0893510051792_,0.034799258,0.020443537,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,obinutuzumab,DB08935
,15442,DB01164,10019909,41,6483,92,7844,0.000835591,0.539237932,0.363183598,0.788540418,0.004746205,DB0116410019909_,5.350410009,-0.617598373,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,15443,DB06228,10013573,443,15469,316,15760,1.69534676768192e-06,1.428247531,1.231337833,1.658195142,2.29297342838258e-05,DB0622810013573_,10.68307605,0.35644819,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,15444,DB00999,10044390,62,21368,35,12204,1,1.01172367,0.657629146,1.578957454,1,DB0099910044390_,0,0.01165548,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,15446,DB06228,10048632,19,15893,59,16017,6.38891832533645e-06,0.324533029,0.182629464,0.55250946,7.33330647080649e-05,DB0622810048632_,9.520498963,-1.125367965,male,10048632,Atrial thrombosis,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,15455,DB00264,10047513,236,29371,150,24742,0.007598579,1.325360234,1.074727121,1.63864311,0.028583706,DB0026410047513_,3.554918431,0.281684297,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,metoprolol,DB00264
,15456,DB00682,10047513,110,19349,84,16280,0.516325677,1.101779716,0.821202712,1.48283604,0.675978504,DB0068210047513_,0.391594002,0.096926796,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,warfarin,DB00682
,15457,DB01373,10047513,172,22548,42,7339,0.110324646,1.332904743,0.94539915,1.917179215,0.226526838,DB0137310047513_,1.484891851,0.287360578,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,calcium,DB01373
,15462,DB00524,10013573,111,1466,64,1280,0.009843776,1.514108635,1.092558701,2.112860818,0.035126225,DB0052410013573_,3.348807286,0.414826906,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,metolazone,DB00524
,15464,DB01062,10013781,87,4399,33,1712,1,1.026029757,0.677059517,1.588164929,1,DB0106210013781_,0,0.025696749,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,oxybutynin,DB01062
,15467,DB00524,10013968,314,1263,155,1189,5.88661333661811e-10,1.906683768,1.542117262,2.364426165,1.70313298352237e-08,DB0052410013968_,17.88821126,0.645365486,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metolazone,DB00524
,15468,DB01062,10013968,144,4342,56,1689,1,1.000263169,0.725738305,1.394841811,1,DB0106210013968_,0,0.000263135,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxybutynin,DB01062
,15469,DB00524,10020919,106,1471,47,1297,8.38902858387557e-05,1.988091265,1.385109293,2.890036092,0.000686719,DB0052410020919_,7.283584715,0.687175015,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,metolazone,DB00524
,15471,DB00524,10021015,36,1541,53,1291,0.009591938,0.569167557,0.359591785,0.891869888,0.034441545,DB0052410021015_,3.368491743,-0.563580412,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,metolazone,DB00524
,15473,DB01062,10021097,52,4434,35,1710,0.015531702,0.573043672,0.364782316,0.909812389,0.050654605,DB0106210021097_,2.982725133,-0.556793348,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,oxybutynin,DB01062
,15476,DB00524,10047895,45,1532,34,1310,0.647717885,1.13168176,0.704202405,1.833707342,0.78282977,DB0052410047895_,0.244840014,0.123704809,NA,10047895,Weight decreased,10022891,Investigations,Inv,metolazone,DB00524
,15477,DB01062,10047895,76,4410,33,1712,0.591450023,0.894080428,0.584362296,1.394712522,0.737822975,DB0106210047895_,0.304051354,-0.111959543,NA,10047895,Weight decreased,10022891,Investigations,Inv,oxybutynin,DB01062
,15479,DB01062,10049848,70,4416,28,1717,0.909859429,0.972036935,0.616413982,1.571107014,0.959437782,DB0106210049848_,0.04140781,-0.028361476,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,15491,DB14726,10055798,48,1969,123,2725,0.000261201,0.540145779,0.376642442,0.764033463,0.001801303,DB1472610055798_,6.319244892,-0.615916215,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,dabigatran,DB14726
,15495,DB01162,10021097,7,266,65,1637,0.38487627,0.662874765,0.253647205,1.466053939,0.554996311,DB0116210021097_,0.588793812,-0.411169198,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,terazosin,DB01162
,15496,DB06700,10002855,128,2097,34,584,0.92185015,1.048460009,0.704575069,1.596747304,0.965486617,DB0670010002855_,0.035123039,0.047322429,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,desvenlafaxine,DB06700
,15498,DB06700,10022998,39,2186,11,607,1,0.984492906,0.490823709,2.144586806,1,DB0670010022998_,0,-0.015628587,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,desvenlafaxine,DB06700
,15499,DB06700,10028813,187,2038,23,595,3.80965277956634e-05,2.373189275,1.517267236,3.873454478,0.000350166,DB0670010028813_,7.957103018,0.864234736,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,desvenlafaxine,DB06700
,15501,DB06700,10042458,100,2125,14,604,0.010622876,2.029726621,1.144588845,3.875259606,0.037349156,DB0670010042458_,3.287444957,0.707901114,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,desvenlafaxine,DB06700
,15502,DB06700,10047700,57,2168,13,605,0.659506291,1.223480289,0.656278452,2.453146895,0.792035804,DB0670010047700_,0.233148681,0.201699494,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,desvenlafaxine,DB06700
,15504,DB00005,10036018,130,127952,37,42382,0.47375424,1.163789932,0.802128326,1.725779206,0.639646096,DB0000510036018_,0.44684023,0.151681862,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,etanercept,DB00005
,15507,DB00335,10016766,33,8433,19,5446,0.776620652,1.121662097,0.618646216,2.090071571,0.878244405,DB0033510016766_,0.129830358,0.1148116,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,15508,DB00497,10016766,63,19204,41,16334,0.200504961,1.306934152,0.867677375,1.98774673,0.349649896,DB0049710016766_,1.050822921,0.267684052,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,15509,DB00695,10016766,101,27948,64,20464,0.38592477,1.15549983,0.836132774,1.607066633,0.556050682,DB0069510016766_,0.586895834,0.144533003,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,15512,DB00996,10016766,88,38865,48,22377,0.789867676,1.055567544,0.734082022,1.534014463,0.886130966,DB0099610016766_,0.120890522,0.054078578,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,15513,DB01373,10016766,81,22639,31,7350,0.441560501,0.848342242,0.553912914,1.329272064,0.609795497,DB0137310016766_,0.494631628,-0.164471137,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,15516,DB11089,10016766,61,10114,30,8377,0.019936705,1.68407467,1.069718074,2.703931599,0.061611462,DB1108910016766_,2.786907349,0.521216256,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,15517,DB00215,10020642,84,11019,40,5236,1,0.99787652,0.675914056,1.495076259,1,DB0021510020642_,0,-0.002125737,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,citalopram,DB00215
,15518,DB00497,10020642,171,19096,168,16207,0.188879262,0.863872311,0.693372137,1.076469532,0.335135103,DB0049710020642_,1.093221537,-0.146330309,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,15519,DB00695,10020642,194,27855,90,20438,0.000287593,1.581574231,1.224751069,2.055324085,0.001949372,DB0069510020642_,6.240247898,0.4584207,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,15520,DB00813,10020642,105,10467,98,10070,0.832841433,1.030795472,0.774105515,1.373604503,0.912990807,DB0081310020642_,0.091029468,0.030330807,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,fentanyl,DB00813
,15521,DB00829,10020642,83,7969,38,4416,0.390597239,1.210320063,0.813467625,1.830115167,0.560453534,DB0082910020642_,0.579008941,0.190884839,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,diazepam,DB00829
,15522,DB01373,10020642,144,22576,43,7338,0.670486092,1.088487244,0.768572779,1.569754358,0.800083838,DB0137310020642_,0.22303876,0.084788882,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,15525,DB11089,10020642,75,10100,72,8335,0.361695363,0.859641553,0.61291123,1.206454583,0.531467719,DB1108910020642_,0.632112818,-0.151239775,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,docusate,DB11089
,15529,DB01270,10014801,78,1180,32,937,0.001573282,1.934970522,1.254414355,3.046467495,0.007993374,DB0127010014801_,4.829142365,0.660092092,NA,10014801,Endophthalmitis,10021881,Infections and infestations,Infec,ranibizumab,DB01270
,15533,DB01270,10047531,101,1157,78,891,1,0.997175537,0.724832432,1.375856884,1,DB0127010047531_,0,-0.002828459,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,ranibizumab,DB01270
,15534,DB00559,10019211,610,9049,132,3174,3.55460185639822e-07,1.620898178,1.334590026,1.980154683,5.68923417088608e-06,DB0055910019211_,12.07693491,0.482980427,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,bosentan,DB00559
,15535,DB00682,10021097,701,18758,480,15884,0.000405821,1.236650894,1.097309854,1.394594806,0.002594434,DB0068210021097_,5.95438691,0.212406834,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,warfarin,DB00682
,15536,DB01240,10021097,467,5284,128,1448,1,0.999790322,0.813087275,1.236069089,1,DB0124010021097_,0,-0.0002097,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,epoprostenol,DB01240
,15544,DB00005,10029410,170,127912,67,42352,0.229261933,0.840083576,0.629504662,1.132210038,0.385008301,DB0000510029410_,0.954490385,-0.174253897,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,15545,DB00413,10028813,156,2043,35,1172,1.33112181923351e-07,2.556300948,1.748374504,3.829137527,2.35771812793482e-06,DB0041310028813_,12.9578163,0.938561271,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pramipexole,DB00413
,15546,DB00413,10047700,58,2141,15,1192,0.006369333,2.152338548,1.197601189,4.107841595,0.024839455,DB0041310047700_,3.695321943,0.766554948,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pramipexole,DB00413
,15548,DB00182,10048393,72,5122,17,2835,0.001102104,2.343998207,1.364192563,4.251743694,0.005963729,DB0018210048393_,5.122059362,0.851858107,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,15549,DB00264,10048393,107,29500,20,24872,1.25695750966333e-12,4.510508162,2.779245796,7.68120152,5.58565141868143e-11,DB0026410048393_,23.60823496,1.506409822,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,15550,DB00285,10048393,79,10872,13,3705,0.011365759,2.070938767,1.14234249,4.064659589,0.039423195,DB0028510048393_,3.233400929,0.728002015,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,15551,DB08880,10048393,223,3115,67,742,0.123955567,0.792869659,0.593314585,1.070632128,0.247005068,DB0888010048393_,1.398346426,-0.232096436,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,teriflunomide,DB08880
,15552,DB08880,10001760,563,2775,47,762,5.7582483990608e-18,3.288465281,2.41035776,4.57754828,4.95494371590795e-16,DB0888010001760_,35.24097568,1.190420976,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,teriflunomide,DB08880
,15553,DB00678,10013700,344,15255,126,10598,2.31445914654529e-10,1.896652428,1.539636556,2.348611914,7.13195295040363e-09,DB0067810013700_,18.75868073,0.640090452,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,losartan,DB00678
,15554,DB00814,10013700,479,7808,94,3321,5.20880104875773e-13,2.16726647,1.727069071,2.743542362,2.41682851838653e-11,DB0081410013700_,24.44597987,0.773466682,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,meloxicam,DB00814
,15555,DB01136,10013700,163,9721,85,11030,3.87924873380465e-09,2.175806424,1.661387155,2.866749194,9.55185507897474e-08,DB0113610013700_,16.16394536,0.777399365,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,carvedilol,DB01136
,15560,DB00007,10028813,100,1847,149,4303,0.000925083,1.563455722,1.193938609,2.040346296,0.005166981,DB0000710028813_,5.265466742,0.446898578,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,leuprolide,DB00007
,15561,DB00007,10047700,50,1897,86,4366,0.109556913,1.338065543,0.920769446,1.926541015,0.225420525,DB0000710047700_,1.48978762,0.291224946,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,leuprolide,DB00007
,15562,DB00007,10047895,10,1937,87,4365,3.36034721330429e-06,0.259030565,0.1197459,0.500946405,4.17620456272829e-05,DB0000710047895_,10.08352263,-1.350809214,male,10047895,Weight decreased,10022891,Investigations,Inv,leuprolide,DB00007
,15563,DB00007,10060800,118,1829,222,4230,0.07925667,1.229218005,0.968093637,1.55467231,0.177170691,DB0000710060800_,1.730641655,0.206378199,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,leuprolide,DB00007
,15564,DB00007,10061428,15,1932,112,4340,7.9579687616253e-07,0.300909893,0.162557209,0.519544917,1.17152175244649e-05,DB0000710061428_,11.35462192,-1.200944417,male,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,leuprolide,DB00007
,15565,DB00203,10000060,284,13594,97,8841,1.6350532110727e-08,1.904093051,1.5045258,2.427108308,3.49267721996459e-07,DB0020310000060_,14.8674271,0.644005806,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,15566,DB00203,10010774,224,13654,121,8817,0.119895508,1.19538816,0.952395828,1.506374043,0.241222659,DB0020310010774_,1.422034875,0.178470953,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,15569,DB00497,10014625,78,19189,53,16322,0.219527337,1.251804774,0.871294163,1.810700019,0.372883499,DB0049710014625_,0.986489243,0.224586329,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,15570,DB00722,10014625,60,25343,44,25988,0.095531502,1.398326403,0.931606077,2.113438215,0.204058798,DB0072210014625_,1.5893471,0.335276095,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,15572,DB00924,10014625,64,10098,10,4241,0.00193458,2.687680594,1.369152183,5.877291531,0.009476413,DB0092410014625_,4.65894937,0.988678589,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,15574,DB01068,10014625,56,13707,36,6804,0.224257138,0.772195988,0.498565349,1.209702979,0.378830262,DB0106810014625_,0.970667033,-0.258516891,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,15576,DB00264,10027091,124,29483,38,24854,7.2317897333289e-09,2.750677964,1.89793682,4.069592127,1.67478055630441e-07,DB0026410027091_,15.60241351,1.011847414,female,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,15578,DB00497,10027091,63,19204,41,16334,0.200504961,1.306934152,0.867677375,1.98774673,0.349649896,DB0049710027091_,1.050822921,0.267684052,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,15579,DB00722,10027091,46,25357,45,25987,0.834607012,1.047635392,0.67901386,1.617199013,0.91418995,DB0072210027091_,0.089716907,0.046535617,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,15584,DB01068,10027091,34,13729,21,6819,0.473741709,0.80418577,0.453086762,1.459281619,0.639645606,DB0106810027091_,0.446840997,-0.217924979,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,15589,DB00030,10020993,70,2136,72,1749,0.198004326,0.796124785,0.561005247,1.129231381,0.346622958,DB0003010020993_,1.059517667,-0.22799934,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,insulin human,DB00030
,15591,DB00115,10020993,37,18388,32,10440,0.102251126,0.656514244,0.397637344,1.089254126,0.21434956,DB0011510020993_,1.54014714,-0.420810889,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,cyanocobalamin,DB00115
,15592,DB00193,10020993,58,19262,26,8676,1,1.004784748,0.622033382,1.664053524,1,DB0019310020993_,0,0.004773338,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,tramadol,DB00193
,15593,DB00213,10020993,44,18851,64,13357,0.000258917,0.487137005,0.323879101,0.726792146,0.0017886,DB0021310020993_,6.326322058,-0.719209872,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,15595,DB00635,10020993,41,33012,33,23761,0.638944639,0.894261032,0.551485597,1.460196224,0.776038407,DB0063510020993_,0.253553266,-0.111757564,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,15604,DB00115,10048294,56,18369,44,10428,0.117844646,0.722553986,0.477752373,1.098770048,0.237968666,DB0011510048294_,1.435616268,-0.32496314,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,15605,DB00193,10048294,79,19241,58,8644,0.005356306,0.611919073,0.430106352,0.875086619,0.021610209,DB0019310048294_,3.834589434,-0.491155238,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,15606,DB00213,10048294,110,18785,90,13331,0.349469777,0.867370992,0.64988172,1.160173593,0.519075133,DB0021310048294_,0.655706642,-0.142288491,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,15607,DB00471,10048294,49,14140,16,5449,0.677611846,1.180151081,0.659069209,2.225288585,0.804591725,DB0047110048294_,0.217420304,0.165642465,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,montelukast,DB00471
,15608,DB00635,10048294,138,32915,135,23659,0.011639118,0.734778136,0.574965241,0.93912546,0.040185765,DB0063510048294_,3.214242449,-0.308186681,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,15610,DB01222,10048294,26,9248,30,5375,0.011946178,0.503725075,0.285839651,0.88226547,0.041008918,DB0122210048294_,3.193965732,-0.685724646,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,budesonide,DB01222
,15613,DB06724,10048294,43,7886,23,3896,0.793348534,0.923648191,0.543457481,1.608125732,0.887941952,DB0672410048294_,0.118848907,-0.079424026,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,calcium carbonate,DB06724
,15616,DB00115,10063743,36,18389,23,10449,0.685150057,0.889394936,0.512533204,1.572920052,0.809887557,DB0011510063743_,0.210859859,-0.117213895,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,cyanocobalamin,DB00115
,15625,DB08880,10013709,175,3163,60,749,0.021749794,0.690736516,0.506459147,0.952655016,0.066052356,DB0888010013709_,2.717307576,-0.369996836,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,teriflunomide,DB08880
,15626,DB01233,10013700,391,3030,58,1668,2.74812761204571e-25,3.710323509,2.790014629,5.009358426,4.26162444145259e-23,DB0123310013700_,51.50980673,1.311119072,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,metoclopramide,DB01233
,15627,DB00374,10025082,173,17543,57,5667,0.87765105,0.980439127,0.721719302,1.34909328,0.948114907,DB0037410025082_,0.053279574,-0.019754719,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,15628,DB06403,10025082,140,21331,59,6602,0.053880719,0.734421871,0.537364512,1.014566633,0.132286074,DB0640310025082_,2.022788473,-0.30867166,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,15629,DB08931,10025082,101,6476,43,2403,0.450537557,0.871593082,0.602218996,1.280224295,0.618232874,DB0893110025082_,0.480890074,-0.137432614,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,15630,DB00115,10007554,46,18379,59,10413,3.7600841548551e-05,0.441740849,0.293498327,0.661248005,0.000346178,DB0011510007554_,7.968557535,-0.817031884,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,cyanocobalamin,DB00115
,15631,DB00213,10007554,68,18827,81,13340,0.001948639,0.5948622,0.424165539,0.832092256,0.009533732,DB0021310007554_,4.652919078,-0.519425496,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,15632,DB00404,10007554,32,19860,24,9838,0.154351189,0.660483645,0.376757277,1.172570022,0.289949687,DB0040410007554_,1.238047863,-0.414782916,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,alprazolam,DB00404
,15634,DB00524,10007554,59,1518,57,1287,0.506871276,0.877614913,0.594571816,1.296269189,0.667540722,DB0052410007554_,0.404154884,-0.130547378,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,metolazone,DB00524
,15636,DB00695,10007554,280,27769,274,20254,0.000623871,0.745359871,0.628086904,0.884563889,0.003721628,DB0069510007554_,5.593594018,-0.293888129,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,furosemide,DB00695
,15638,DB00761,10007554,128,15179,110,8515,0.001376435,0.652750238,0.501265041,0.851299452,0.007164276,DB0076110007554_,4.938648209,-0.426560706,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,15642,DB01136,10007554,84,9800,111,11004,0.279908779,0.849736847,0.63138268,1.140044852,0.443765026,DB0113610007554_,0.812460077,-0.16282857,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,carvedilol,DB01136
,15670,DB06228,10028372,76,15836,55,16021,0.065683161,1.397940157,0.974454754,2.016698104,0.153628928,DB0622810028372_,1.873215143,0.334999836,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,rivaroxaban,DB06228
,15671,DB01136,10013573,396,9488,409,10706,0.221075205,1.092502469,0.946416904,1.261039277,0.374828211,DB0113610013573_,0.981287463,0.088470908,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,15672,DB01136,10037844,226,9658,192,10923,0.004062793,1.331231226,1.091178141,1.625356065,0.017308025,DB0113610037844_,4.056585018,0.286104248,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,carvedilol,DB01136
,15673,DB01136,10037884,40,9844,29,11086,0.071125154,1.553288378,0.938428332,2.600097357,0.163263005,DB0113610037884_,1.81239285,0.440374218,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,carvedilol,DB01136
,15674,DB01136,10057362,27,9857,32,11083,0.896470948,0.948683508,0.546404649,1.635838021,0.956301489,DB0113610057362_,0.044682051,-0.052680037,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,15675,DB08880,10037844,120,3218,29,780,1,1.0029783,0.65829915,1.573255327,1,DB0888010037844_,0,0.002973873,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,teriflunomide,DB08880
,15678,DB00588,10001053,95,16429,57,8411,0.345422569,0.853282085,0.60739021,1.208036871,0.514858196,DB0058810001053_,0.663863763,-0.158665088,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,15685,DB09053,10008479,27,2258,47,4005,1,1.018936487,0.608414669,1.675235067,1,DB0905310008479_,0,0.018759424,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ibrutinib,DB09053
,15689,DB00295,10018884,84,14579,65,9537,0.314311518,0.845386839,0.603619857,1.188562963,0.481939863,DB0029510018884_,0.729935939,-0.167960959,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,morphine,DB00295
,15690,DB00448,10018884,40,5105,31,3093,0.326147739,0.781813046,0.475824564,1.295505903,0.494684248,DB0044810018884_,0.703835603,-0.246139639,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,lansoprazole,DB00448
,15691,DB01222,10018884,78,9196,66,5339,0.02960313,0.686182436,0.487109438,0.969038978,0.083831402,DB0122210018884_,2.478947611,-0.376611745,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,budesonide,DB01222
,15692,DB01409,10018884,74,5957,47,3919,0.925575812,1.035812759,0.707347757,1.529951,0.968231792,DB0140910018884_,0.032283766,0.035186393,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,tiotropium,DB01409
,15696,DB01222,10018964,47,9227,33,5372,0.417500586,0.829219749,0.519428258,1.337782507,0.586562773,DB0122210018964_,0.533475588,-0.187270082,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,15697,DB01409,10018964,34,5997,34,3932,0.082978639,0.655708365,0.394691,1.089233358,0.183385338,DB0140910018964_,1.69616567,-0.422039154,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,15704,DB00295,10040047,173,14490,181,9421,1.08986759979721e-05,0.621468213,0.500741894,0.771016076,0.000116808,DB0029510040047_,9.054978722,-0.475670515,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,morphine,DB00295
,15705,DB00448,10040047,40,5105,37,3087,0.075817436,0.653790583,0.406543183,1.053802375,0.171183532,DB0044810040047_,1.765019012,-0.424968189,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,lansoprazole,DB00448
,15706,DB00682,10040047,325,19134,233,16131,0.065453146,1.17592813,0.98943352,1.399325202,0.153227284,DB0068210040047_,1.875832944,0.162057733,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,warfarin,DB00682
,15707,DB01222,10040047,112,9162,83,5322,0.100157014,0.783862616,0.583627798,1.056331912,0.211015319,DB0122210040047_,1.555824546,-0.243521509,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,budesonide,DB01222
,15708,DB01409,10040047,70,5961,55,3911,0.357610351,0.835054595,0.576773859,1.21423111,0.527322548,DB0140910040047_,0.639942873,-0.180258173,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,tiotropium,DB01409
,15710,DB00448,10046571,91,5054,21,3103,1.89640050985498e-05,2.660245368,1.637207285,4.512739824,0.000190728,DB0044810046571_,8.564659729,0.978418362,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,lansoprazole,DB00448
,15711,DB01222,10046571,202,9072,45,5360,1.54301867906191e-10,2.651999048,1.907908948,3.756686197,4.88065535248404e-09,DB0122210046571_,19.13798633,0.975313713,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,budesonide,DB01222
,15712,DB01409,10046571,108,5923,27,3939,1.2489226477821e-06,2.659896044,1.727613038,4.228560651,1.74482070714753e-05,DB0140910046571_,10.95627366,0.978287041,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,tiotropium,DB01409
,15728,DB00996,10051118,760,38193,382,22043,0.029881499,1.148275517,1.012887337,1.303336245,0.084455398,DB0099610051118_,2.47153172,0.138261266,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,15732,DB08880,10013573,113,3225,17,792,0.071072523,1.632201342,0.968504959,2.917678274,0.163177819,DB0888010013573_,1.812914759,0.48992962,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,teriflunomide,DB08880
,15733,DB00169,10001949,156,38535,62,18113,0.275893628,1.182664687,0.875312577,1.614938491,0.439227401,DB0016910001949_,0.822738001,0.167770102,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,15734,DB00181,10001949,61,9795,32,5839,0.592365815,1.13636936,0.728195028,1.803971886,0.738542854,DB0018110001949_,0.30307615,0.127838409,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,15735,DB00295,10001949,39,14624,24,9578,0.89757941,1.064300763,0.623697437,1.851367845,0.956338178,DB0029510001949_,0.044643686,0.062318023,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,morphine,DB00295
,15748,DB00669,10013709,475,5902,69,1028,0.186405893,1.199024223,0.921066863,1.580451152,0.331967811,DB0066910013709_,1.10271727,0.181508078,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,15753,DB00316,10006093,209,65265,135,36818,0.237573309,0.87336399,0.699782182,1.093017697,0.395003759,DB0031610006093_,0.928859997,-0.135402868,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,15755,DB00390,10006093,59,4086,69,3232,0.03107476,0.67640202,0.468050463,0.974804161,0.08708528,DB0039010006093_,2.44086741,-0.390967675,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,digoxin,DB00390
,15756,DB00472,10006093,67,10692,43,4269,0.019334844,0.622140618,0.417214559,0.936503663,0.060193815,DB0047210006093_,2.810185678,-0.474589138,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,fluoxetine,DB00472
,15757,DB00641,10006093,58,14066,47,12428,0.695780119,1.090298093,0.728759771,1.638781176,0.816873861,DB0064110006093_,0.202270589,0.086451139,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,simvastatin,DB00641
,15758,DB00727,10006093,26,3817,62,4111,0.000532512,0.451719355,0.273611998,0.72654713,0.003249092,DB0072710006093_,5.72937958,-0.794694187,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,nitroglycerin,DB00727
,15763,DB11089,10006093,42,10133,53,8354,0.049034439,0.653348996,0.424699205,0.999373273,0.123179773,DB1108910006093_,2.094110418,-0.425643842,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,docusate,DB11089
,15765,DB00213,10014625,55,18840,62,13359,0.014238791,0.629043234,0.429128695,0.919946784,0.047217134,DB0021310014625_,3.05299845,-0.46355529,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,15769,DB00472,10014625,44,10715,13,4299,0.38038219,1.357887089,0.717474667,2.7506988,0.55043331,DB0047210014625_,0.597049474,0.305929881,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,15771,DB01136,10014625,34,9850,31,11084,0.455604658,1.23416103,0.735400551,2.07818948,0.623013654,DB0113610014625_,0.473186845,0.210391411,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,15775,DB11089,10014625,49,10126,40,8367,1,1.012203764,0.652307982,1.579017176,1,DB1108910014625_,0,0.012129899,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,docusate,DB11089
,15776,DB00030,10028813,111,2095,58,1763,0.003473922,1.610319804,1.153962272,2.266928919,0.015229893,DB0003010028813_,4.184495138,0.476432795,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,insulin human,DB00030
,15777,DB00243,10028813,77,1177,46,1580,1.60614555233021e-05,2.246436091,1.526282515,3.33804759,0.000164399,DB0024310028813_,8.713217175,0.809345001,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ranolazine,DB00243
,15778,DB00370,10028813,245,4296,141,3522,0.001123621,1.424468123,1.147427841,1.773762638,0.006063311,DB0037010028813_,5.105499324,0.353798497,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,mirtazapine,DB00370
,15779,DB00390,10028813,332,3813,113,3188,2.51373608760849e-17,2.456074865,1.967425999,3.084638871,2.02059795299049e-15,DB0039010028813_,33.83538291,0.898564492,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,digoxin,DB00390
,15780,DB00472,10028813,608,10151,146,4166,2.92932476159548e-09,1.709020719,1.418897661,2.069170166,7.4178517686452e-08,DB0047210028813_,16.41679125,0.535920528,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,15781,DB01377,10028813,302,3494,110,2560,2.1755985886865e-10,2.011324258,1.601614529,2.540741824,6.72854849783478e-09,DB0137710028813_,18.81690639,0.69879334,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,magnesium oxide,DB01377
,15782,DB01593,10028813,99,1034,27,671,3.94992274539074e-05,2.378411226,1.521497269,3.830513314,0.000360588,DB0159310028813_,7.927773688,0.866432713,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,zinc,DB01593
,15783,DB06723,10028813,82,948,39,571,0.282319414,1.266235659,0.841644337,1.932453923,0.446367357,DB0672310028813_,0.806612995,0.236048451,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,aluminum hydroxide,DB06723
,15784,DB00030,10047700,72,2134,37,1784,0.01888684,1.62659463,1.073678533,2.500936974,0.059071941,DB0003010047700_,2.828999243,0.486488645,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,insulin human,DB00030
,15785,DB00243,10047700,34,1220,23,1603,0.014972444,1.941850791,1.104528135,3.471817095,0.049243081,DB0024310047700_,3.010986412,0.663641534,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ranolazine,DB00243
,15786,DB00370,10047700,143,4398,90,3573,0.061511359,1.290795657,0.980849999,1.706069573,0.146239694,DB0037010047700_,1.922508263,0.255258816,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,mirtazapine,DB00370
,15787,DB00390,10047700,182,3963,76,3225,7.64843374992114e-07,1.948585809,1.476643779,2.592074421,1.13070349334464e-05,DB0039010047700_,11.39008547,0.667103884,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,digoxin,DB00390
,15788,DB00472,10047700,336,10423,93,4219,0.001123186,1.462429835,1.155585687,1.865695921,0.006062207,DB0047210047700_,5.105681402,0.380099323,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,15789,DB00727,10047700,134,3709,89,4084,0.00023395,1.657723663,1.253660513,2.200729199,0.001641586,DB0072710047700_,6.412092725,0.505445374,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,nitroglycerin,DB00727
,15790,DB01136,10047700,318,9566,182,10933,6.42559608997954e-14,1.996852429,1.655456928,2.414352466,3.37456130319904e-12,DB0113610047700_,26.41475578,0.691572155,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,15791,DB01233,10047700,250,3171,102,1624,0.061438047,1.255152654,0.984994161,1.608805474,0.146105046,DB0123310047700_,1.923429423,0.227257202,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,metoclopramide,DB01233
,15792,DB01377,10047700,194,3602,63,2607,1.35269231772219e-08,2.228455891,1.660957766,3.024061184,2.95066535861642e-07,DB0137710047700_,15.03606496,0.80130892,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,magnesium oxide,DB01377
,15793,DB01593,10047700,44,1089,13,685,0.01783431,2.128191448,1.115808605,4.339620993,0.056461889,DB0159310047700_,2.874189392,0.755272534,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,zinc,DB01593
,15794,DB06723,10047700,61,969,23,587,0.063449039,1.60619506,0.967532051,2.750182838,0.149702256,DB0672310047700_,1.899106916,0.473868065,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,aluminum hydroxide,DB06723
,15795,DB11089,10047700,412,9763,228,8179,6.19964419259368e-07,1.513800377,1.28101518,1.792406636,9.37615924064009e-06,DB1108910047700_,11.57734034,0.414623295,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,15811,DB00213,10070863,103,18792,116,13305,0.000714981,0.628691618,0.476939423,0.827720268,0.004165641,DB0021310070863_,5.480885206,-0.464114416,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,15813,DB00472,10070863,721,10038,297,4015,0.692853139,0.970996376,0.842791094,1.120811294,0.814954759,DB0047210070863_,0.204622678,-0.029432543,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,15814,DB00641,10070863,121,14003,152,12323,0.00409325,0.70056175,0.546406251,0.896564143,0.017403927,DB0064110070863_,4.051059388,-0.355872766,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,15815,DB00727,10070863,53,3790,28,4145,0.001650564,2.069956576,1.282860072,3.406248148,0.00830734,DB0072710070863_,4.790615812,0.727527629,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,nitroglycerin,DB00727
,15816,DB01136,10070863,176,9708,165,10950,0.100707908,1.20311792,0.965548657,1.499644614,0.211955109,DB0113610070863_,1.551380775,0.184916454,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,15817,DB01233,10070863,40,3381,11,1715,0.074270185,1.844336943,0.925855392,3.996279559,0.168626744,DB0123310070863_,1.780067625,0.612119833,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,metoclopramide,DB01233
,15821,DB11089,10070863,49,10126,39,8368,0.914702317,1.038286019,0.667170996,1.625623585,0.961865977,DB1108910070863_,0.038880155,0.037571295,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,15822,DB00046,10057362,114,5345,88,4604,0.476205522,1.115827851,0.835033537,1.495172795,0.641621308,DB0004610057362_,0.443757012,0.109596597,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin lispro,DB00046
,15828,DB01225,10017955,93,4951,103,4537,0.19420919,0.827429618,0.616458943,1.109368705,0.34200647,DB0122510017955_,1.072925625,-0.189431229,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,15831,DB08910,10017955,25,16719,32,17456,0.507953646,0.81569475,0.463244113,1.421255301,0.668631173,DB0891010017955_,0.402522682,-0.203715075,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,15832,DB00626,10013700,415,452,70,376,2.34236169636891e-32,4.925914303,3.672930385,6.673067431,6.0067294818592e-30,DB0062610013700_,67.28467237,1.594509903,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,bacitracin,DB00626
,15846,DB01175,10069326,69,10655,19,4873,0.050145789,1.660832085,0.986523137,2.926715463,0.125304883,DB0117510069326_,2.07700545,0.507318733,NA,10069326,Product substitution issue,10077536,Product issues,Prod,escitalopram,DB01175
,15848,DB00852,10012735,60,1106,24,447,1,1.010394585,0.610920478,1.718981378,1,DB0085210012735_,0,0.010340933,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pseudoephedrine,DB00852
,15849,DB01112,10012735,72,1073,25,554,0.097889112,1.486650169,0.919428236,2.475553041,0.207710619,DB0111210012735_,1.571609421,0.39652538,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cefuroxime,DB01112
,15859,DB00695,10044066,71,27978,8,20520,6.12802702731411e-10,6.508596949,3.129453111,15.65877425,1.76908501277267e-08,DB0069510044066_,17.85021827,1.873123911,female,10044066,Torsade de pointes,10007541,Cardiac disorders,Card,furosemide,DB00695
,15861,DB00502,10048294,28,1366,43,1829,0.628499371,0.871926183,0.51877871,1.444284165,0.767769948,DB0050210048294_,0.264265138,-0.137050511,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,haloperidol,DB00502
,15862,DB00695,10048294,166,27883,149,20379,0.075958419,0.814272339,0.648236643,1.023584061,0.171423289,DB0069510048294_,1.763619409,-0.2054604,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,15863,DB00230,10013709,1743,17931,760,7891,0.855741514,1.009278983,0.922485775,1.104950962,0.930296159,DB0023010013709_,0.072252293,0.009236198,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,15864,DB06643,10013709,315,52106,80,7435,1.67467155315585e-05,0.561849067,0.437740239,0.728296853,0.000170781,DB0664310013709_,8.675129909,-0.576522029,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,15865,DB00773,10043554,96,2227,151,2676,0.049130376,0.763982219,0.581540648,0.999771818,0.123348005,DB0077310043554_,2.092745607,-0.269210764,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,etoposide,DB00773
,15867,DB01164,10064882,108,6416,112,7824,0.246013385,1.175883479,0.892374481,1.548955781,0.404976473,DB0116410064882_,0.903926305,0.162019762,NA,10064882,Procedural pain,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium chloride,DB01164
,15868,DB00051,10012174,126,25605,66,11354,0.273091465,0.846564949,0.623121793,1.159232735,0.4360737,DB0005110012174_,0.829944014,-0.166568354,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,adalimumab,DB00051
,15870,DB08900,10012174,64,947,25,412,0.721455427,1.113662883,0.680270328,1.873403028,0.835799546,DB0890010012174_,0.179366472,0.107654477,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,teduglutide,DB08900
,15872,DB00051,10025482,500,25231,164,11256,0.000579305,1.360150341,1.136261339,1.634848169,0.003491236,DB0005110025482_,5.65749934,0.307595239,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,15873,DB00476,10025482,562,16695,132,6045,5.10877394286634e-06,1.541637774,1.270060796,1.882156872,6.04067130401448e-05,DB0047610025482_,9.714410316,0.432845341,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,15874,DB00669,10025482,147,6230,17,1080,0.119301682,1.498934327,0.900244428,2.653997021,0.240266996,DB0066910025482_,1.426004489,0.404754407,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,15877,DB08908,10020937,215,10458,40,3239,0.00276699,1.664606771,1.180326047,2.400998889,0.012650953,DB0890810020937_,4.370022769,0.509588922,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,15878,DB08908,10028372,180,10493,79,3200,0.009456405,0.694877537,0.528830154,0.91998439,0.034035548,DB0890810028372_,3.380349778,-0.364019655,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,dimethyl fumarate,DB08908
,15879,DB08908,10033775,178,10495,56,3223,0.876502011,0.976135437,0.717122327,1.346340877,0.947243457,DB0890810033775_,0.054199136,-0.024153935,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,15880,DB06285,10047899,160,8690,8,1098,0.006025992,2.526879072,1.247161745,5.971149605,0.023745325,DB0628510047899_,3.740369592,0.926984973,NA,10047899,Weight increased,10022891,Investigations,Inv,teriparatide,DB06285
,15881,DB00005,10018292,41,128041,17,42402,0.447951588,0.798674281,0.443821665,1.49955501,0.615714324,DB0000510018292_,0.484972183,-0.224802074,NA,10018292,Gingivitis,10021881,Infections and infestations,Infec,etanercept,DB00005
,15882,DB00390,10003445,42,4103,22,3279,0.129025786,1.525604186,0.888213448,2.689154363,0.254183459,DB0039010003445_,1.369698995,0.422390519,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,digoxin,DB00390
,15883,DB00695,10003445,182,27867,144,20384,0.499830919,0.92450452,0.738276886,1.159386151,0.66153352,DB0069510003445_,0.413194624,-0.078497339,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,15884,DB00722,10003445,50,25353,42,25990,0.34963469,1.22038021,0.79317892,1.885914704,0.519234668,DB0072210003445_,0.655399345,0.199162458,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,15886,DB14500,10003445,35,7774,16,4057,0.767965229,1.141563185,0.614545292,2.211671916,0.872661351,DB1450010003445_,0.136207713,0.132398538,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,15888,DB00390,10016173,159,3986,131,3170,0.809480207,0.965257009,0.757388977,1.23192643,0.89735512,DB0039010016173_,0.108303598,-0.035360883,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,digoxin,DB00390
,15889,DB01136,10016173,329,9555,340,10775,0.27061138,1.091193044,0.932441919,1.276833471,0.433311207,DB0113610016173_,0.836299085,0.087271634,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,15890,DB14500,10016173,313,7496,159,3914,0.804725026,1.027869316,0.84308705,1.256993531,0.894427482,DB1450010016173_,0.11157145,0.027488034,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium,DB14500
,15891,DB14726,10016173,105,1912,115,2733,0.058543513,1.305009556,0.985363668,1.726881107,0.140762553,DB1472610016173_,1.960680828,0.266210363,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,dabigatran,DB14726
,15893,DB00695,10022116,47,28002,28,20500,0.414739289,1.228860654,0.753503983,2.038655676,0.58396305,DB0069510022116_,0.537917569,0.206087443,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,15894,DB00722,10022116,64,25339,26,26006,3.22183861607795e-05,2.52638354,1.578020354,4.154541213,0.000302126,DB0072210022116_,8.104665108,0.926788849,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,15922,DB00222,10002034,62,3144,51,3077,0.393337118,1.189745515,0.805220457,1.764797112,0.563257124,DB0022210002034_,0.574019052,0.173739431,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,glimepiride,DB00222
,15923,DB00331,10002034,352,24594,280,20472,0.601055674,1.046451919,0.890904185,1.230077221,0.745334479,DB0033110002034_,0.293922197,0.045405318,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,metformin,DB00331
,15924,DB00476,10002034,152,17105,56,6121,0.874399983,0.971303228,0.709475439,1.346190651,0.945593826,DB0047610002034_,0.055942161,-0.029116575,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,duloxetine,DB00476
,15925,DB00489,10002034,30,1053,23,1111,0.268461369,1.375987499,0.76720676,2.497791749,0.430942554,DB0048910002034_,0.841780483,0.319171654,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,sotalol,DB00489
,15926,DB01098,10002034,101,8048,100,7109,0.434496174,0.892165629,0.668563996,1.19063014,0.60302719,DB0109810002034_,0.505792993,-0.114103481,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,rosuvastatin,DB01098
,15928,DB00222,10013573,112,3094,87,3041,0.113000852,1.265254174,0.94316529,1.701979103,0.230554016,DB0022210013573_,1.467270101,0.23527303,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,glimepiride,DB00222
,15929,DB00489,10013573,34,1049,50,1084,0.120827522,0.702801993,0.436941652,1.11846605,0.242652056,DB0048910013573_,1.416126732,-0.352680088,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sotalol,DB00489
,15930,DB00761,10013573,561,14746,264,8361,0.014825239,1.204824196,1.036422614,1.403498478,0.048856927,DB0076110013573_,3.018859108,0.186333661,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,15931,DB14726,10013573,47,1970,77,2771,0.460429255,0.858617092,0.581446254,1.25632692,0.627814648,DB1472610013573_,0.465510303,-0.152432217,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,dabigatran,DB14726
,15933,DB00222,10016173,106,3100,85,3043,0.185976114,1.224087947,0.907270017,1.65562969,0.331426975,DB0022210016173_,1.10434778,0.202196034,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,glimepiride,DB00222
,15934,DB00489,10016173,38,1045,29,1105,0.215064499,1.385369094,0.825336228,2.34753526,0.36750425,DB0048910016173_,1.001020397,0.325966598,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sotalol,DB00489
,15935,DB01098,10016173,227,7922,177,7032,0.206917236,1.138394493,0.92862685,1.397365187,0.35754831,DB0109810016173_,1.028484792,0.12961893,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,rosuvastatin,DB01098
,15947,DB00169,10020993,86,38605,51,18124,0.199069624,0.791688742,0.553227008,1.142944979,0.347897015,DB0016910020993_,1.055848776,-0.233586967,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,15948,DB00222,10020993,96,3110,97,3031,0.826630951,0.964546142,0.716411018,1.298486763,0.908584167,DB0022210020993_,0.095867751,-0.036097607,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,glimepiride,DB00222
,15949,DB00331,10020993,270,24676,286,20466,0.004639573,0.782998011,0.65984545,0.928898963,0.019251903,DB0033110020993_,3.950145363,-0.244625124,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,15950,DB00451,10020993,121,47150,65,15354,0.001538851,0.606200056,0.444565351,0.833060715,0.007857157,DB0045110020993_,4.846330414,-0.500545222,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,15951,DB00476,10020993,41,17216,13,6164,0.759792913,1.12919233,0.592699386,2.298387643,0.866333661,DB0047610020993_,0.143485155,0.121502625,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,duloxetine,DB00476
,15953,DB00761,10020993,42,15265,37,8588,0.059575169,0.638603448,0.400362279,1.02258077,0.142665136,DB0076110020993_,1.947255104,-0.448471599,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,15976,DB00115,10061024,85,18340,84,10388,0.000383047,0.573196462,0.41847918,0.785124993,0.002473502,DB0011510061024_,6.002120438,-0.556526755,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,cyanocobalamin,DB00115
,15977,DB00169,10061024,171,38520,122,18053,0.000528769,0.656896897,0.517342361,0.836218343,0.003231129,DB0016910061024_,5.734923558,-0.420228202,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,15978,DB01373,10061024,114,22606,49,7332,0.100846299,0.754591547,0.534791082,1.078573512,0.212118991,DB0137310061024_,1.550607882,-0.281578673,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,calcium,DB01373
,15980,DB13961,10061024,46,9411,52,6362,0.012876574,0.598052608,0.392742578,0.908058679,0.043534728,DB1396110061024_,3.134196311,-0.514076556,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,fish oil,DB13961
,15986,DB14726,10018867,25,1992,80,2768,0.000182776,0.434308484,0.264480266,0.690867299,0.001336748,DB1472610018867_,6.61751518,-0.834000204,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,dabigatran,DB14726
,15995,DB00472,10071404,108,10651,17,4295,9.17553490120331e-05,2.561609633,1.525673039,4.564149136,0.000741405,DB0047210071404_,7.206963986,0.940635824,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,15996,DB00188,10000081,78,7808,46,8782,0.000548984,1.907082659,1.306376606,2.812218632,0.003333728,DB0018810000081_,5.703664139,0.645574671,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,15997,DB00230,10000081,184,19490,66,8585,0.167747057,1.227982718,0.921041729,1.654495792,0.307864222,DB0023010000081_,1.17809643,0.205372756,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,15998,DB00231,10000081,55,3241,21,2118,0.043690098,1.711392507,1.014869834,2.988729044,0.112961079,DB0023110000081_,2.180711957,0.537307371,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,temazepam,DB00231
,15999,DB00424,10000081,38,1156,18,410,0.354170646,0.748892364,0.411654638,1.410511994,0.524043763,DB0042410000081_,0.646180081,-0.289160013,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,hyoscyamine,DB00424
,16000,DB00451,10000081,707,46564,185,15234,0.006863286,1.250278705,1.060796611,1.47957957,0.026395892,DB0045110000081_,3.634546873,0.223366491,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,16001,DB00695,10000081,442,27607,249,20279,0.000842046,1.303909928,1.112618467,1.530839811,0.004775741,DB0069510000081_,5.344206167,0.265367388,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,16002,DB00829,10000081,114,7938,47,4407,0.097371741,1.346570376,0.948651555,1.937961846,0.206921838,DB0082910000081_,1.575414153,0.297560897,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,diazepam,DB00829
,16003,DB01015,10000081,147,9740,120,9261,0.241415238,1.164746068,0.907336689,1.497583345,0.399535159,DB0101510000081_,0.91745351,0.152503096,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,16007,DB00316,10005654,72,65402,31,36922,0.219343821,1.311191526,0.849301082,2.067771261,0.37269804,DB0031610005654_,0.986986732,0.270936286,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,16009,DB00338,10005654,55,33619,28,22244,0.312495993,1.299662542,0.810027344,2.128623857,0.479955189,DB0033810005654_,0.734062535,0.262104648,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,omeprazole,DB00338
,16011,DB00451,10005654,49,47222,9,15410,0.126946514,1.776601082,0.86336768,4.114891655,0.251396754,DB0045110005654_,1.380722896,0.574702035,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,16012,DB00695,10005654,57,27992,20,20508,0.003703327,2.08797188,1.234985615,3.670509128,0.016031525,DB0069510005654_,4.133198178,0.736193202,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,furosemide,DB00695
,16014,DB00904,10005654,47,23022,22,14434,0.268365497,1.339416085,0.79093598,2.334983864,0.430843614,DB0090410005654_,0.842010098,0.292233761,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,ondansetron,DB00904
,16015,DB00996,10005654,52,38901,19,22406,0.108180758,1.576340832,0.916136746,2.82413967,0.223325149,DB0099610005654_,1.499126501,0.455106232,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,gabapentin,DB00996
,16018,DB00188,10005724,61,7825,36,8792,0.002103111,1.903749787,1.239347683,2.962720818,0.010137587,DB0018810005724_,4.591505288,0.643825513,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,bortezomib,DB00188
,16019,DB00230,10005724,77,19597,19,8632,0.025760432,1.785052945,1.068808645,3.126300726,0.075167958,DB0023010005724_,2.58803023,0.579448076,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,pregabalin,DB00230
,16023,DB00451,10005724,202,47069,38,15381,0.001196546,1.73698449,1.222817162,2.527154252,0.006394471,DB0045110005724_,5.052321556,0.552150558,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,16024,DB00695,10005724,234,27815,95,20433,5.45641662140989e-07,1.809414843,1.418678751,2.323237789,8.39460994403037e-06,DB0069510005724_,11.68792073,0.593003502,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,furosemide,DB00695
,16026,DB01015,10005724,39,9848,13,9368,0.000700945,2.853392875,1.48995019,5.829919196,0.004096117,DB0101510005724_,5.497715878,1.048508769,female,10005724,Blood potassium decreased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,16027,DB01069,10005724,56,6644,8,2387,0.009962963,2.514509611,1.190077354,6.117742354,0.035460595,DB0106910005724_,3.339333197,0.922077799,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,promethazine,DB01069
,16028,DB00188,10010774,244,7642,230,8598,0.061838892,1.193567049,0.990014974,1.439281956,0.146839086,DB0018810010774_,1.918417942,0.176946344,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,16029,DB00230,10010774,267,19407,116,8535,0.955477484,1.012278734,0.809778599,1.271858696,0.9931676,DB0023010010774_,0.006855848,0.012203962,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,16030,DB00231,10010774,88,3208,38,2101,0.033814608,1.516557259,1.021046898,2.290619109,0.093006538,DB0023110010774_,2.375085487,0.416442805,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,temazepam,DB00231
,16031,DB00327,10010774,196,5942,107,4155,0.043814278,1.28085607,1.003353923,1.642357357,0.11320213,DB0032710010774_,2.178580295,0.247528659,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,hydromorphone,DB00327
,16032,DB00338,10010774,731,32943,435,21837,0.079551343,1.113954021,0.986647079,1.258774346,0.17767075,DB0033810010774_,1.727823162,0.107915867,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,16034,DB00497,10010774,475,18792,378,15997,0.347846555,1.069733308,0.930980421,1.229774357,0.517409693,DB0049710010774_,0.658920275,0.067409372,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,16035,DB00829,10010774,145,7907,74,4380,0.618398546,1.085424057,0.812663855,1.460008773,0.759269202,DB0082910010774_,0.275398885,0.081970746,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,diazepam,DB00829
,16036,DB00904,10010774,825,22244,382,14074,4.95550013520888e-07,1.366443025,1.206600322,1.549588772,7.68921611888815e-06,DB0090410010774_,11.77569171,0.312211032,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,16037,DB00996,10010774,618,38335,361,22064,0.840924727,0.985298429,0.862967891,1.126253373,0.918767414,DB0099610010774_,0.084722274,-0.01481071,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,16038,DB01015,10010774,189,9698,148,9233,0.078718967,1.215782154,0.973318105,1.520974058,0.17617847,DB0101510010774_,1.736257763,0.195387618,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,16039,DB01069,10010774,164,6536,39,2356,0.019323821,1.515670388,1.059658047,2.215330205,0.060172218,DB0106910010774_,2.810544532,0.415857841,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,promethazine,DB01069
,16040,DB00188,10020583,17,7869,40,8788,0.01092721,0.474669593,0.25210119,0.857252082,0.038217246,DB0018810020583_,3.264468389,-0.745136312,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,bortezomib,DB00188
,16043,DB00316,10020583,70,65404,57,36896,0.041952978,0.692814826,0.481247732,1.000944051,0.109611519,DB0031610020583_,2.210812813,-0.366992522,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,16045,DB00338,10020583,41,33633,26,22246,0.901294325,1.043033428,0.622742783,1.776590001,0.956927891,DB0033810020583_,0.044027239,0.042133225,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,16047,DB00451,10020583,53,47218,19,15400,0.683527082,0.909768551,0.5296404,1.627871716,0.808682962,DB0045110020583_,0.212348328,-0.094565051,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,16048,DB00497,10020583,33,19234,37,16338,0.280145993,0.757613254,0.458927241,1.245839515,0.443993816,DB0049710020583_,0.811944645,-0.277582243,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,16049,DB00695,10020583,41,28008,31,20497,0.905399231,0.967885025,0.592111574,1.596905436,0.957832006,DB0069510020583_,0.043082876,-0.032641975,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,16051,DB00904,10020583,48,23021,36,14420,0.43300765,0.835189931,0.530630944,1.325202741,0.601453541,DB0090410020583_,0.508405984,-0.180096118,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,16052,DB00996,10020583,35,38918,18,22407,0.776201468,1.119526635,0.616924438,2.100199159,0.877982174,DB0099610020583_,0.130128988,0.112905949,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,16056,DB00230,10024264,83,19591,45,8606,0.250182089,0.810264638,0.556548053,1.193114392,0.409887881,DB0023010024264_,0.891871618,-0.210394371,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,16058,DB00316,10024264,326,65148,227,36726,0.016434422,0.80960239,0.680970732,0.963807964,0.05291945,DB0031610024264_,2.938984341,-0.211212029,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,16059,DB00327,10024264,49,6089,53,4209,0.025929795,0.639121126,0.423485059,0.962784411,0.075536368,DB0032710024264_,2.583141043,-0.447661287,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,16060,DB00338,10024264,128,33546,111,22161,0.039929704,0.761805781,0.58581583,0.991914472,0.105537107,DB0033810024264_,2.248692666,-0.272063636,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,16062,DB00829,10024264,60,7992,34,4420,0.914187483,0.975962737,0.629342818,1.535854638,0.961580583,DB0082910024264_,0.039176908,-0.024330872,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,16063,DB00904,10024264,106,22963,63,14393,0.812230155,1.054604653,0.764393494,1.46532606,0.89905753,DB0090410024264_,0.106408254,0.05316596,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,16064,DB00996,10024264,208,38745,152,22273,0.027981391,0.786670034,0.634694824,0.976804361,0.080186823,DB0099610024264_,2.523396076,-0.239946389,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,16065,DB01015,10024264,40,9847,46,9335,0.388657857,0.82436159,0.525336894,1.288797176,0.558595389,DB0101510024264_,0.58232988,-0.193146023,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,16066,DB01069,10024264,35,6665,31,2364,0.000350411,0.400501108,0.239268521,0.673278751,0.002296038,DB0106910024264_,6.076570442,-0.915038747,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,16067,DB00188,10028813,337,7549,207,8621,2.74306827312777e-12,1.859116864,1.554610899,2.227600873,1.14811384648349e-10,DB0018810028813_,22.88773047,0.620101571,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,16068,DB00231,10028813,239,3057,80,2059,4.44134206052602e-08,2.011937247,1.54551977,2.641873447,8.67637874848952e-07,DB0023110028813_,13.9574914,0.699098063,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,temazepam,DB00231
,16069,DB00424,10028813,92,1102,19,409,0.025067826,1.796545715,1.071175853,3.160333935,0.073604537,DB0042410028813_,2.609048615,0.585865774,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,hyoscyamine,DB00424
,16070,DB00829,10028813,482,7570,143,4311,2.13048781543013e-12,1.919428145,1.583142066,2.338637879,9.09088834879562e-11,DB0082910028813_,23.12116339,0.6520273,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,diazepam,DB00829
,16071,DB01015,10028813,589,9298,349,9032,4.84255259702547e-13,1.639345422,1.428917899,1.882805503,2.25885527973051e-11,DB0101510028813_,24.51357785,0.494297029,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,16072,DB01069,10028813,812,5888,199,2196,2.00236805627596e-07,1.52176982,1.291255726,1.799786117,3.39782081079495e-06,DB0106910028813_,12.59237627,0.419874013,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,promethazine,DB01069
,16073,DB00188,10029331,575,7311,647,8181,0.928888609,0.994473528,0.883317341,1.119431557,0.970519212,DB0018810029331_,0.029924081,-0.0055418,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,16074,DB00230,10029331,369,19305,213,8438,0.001680452,0.757197007,0.636682876,0.90236975,0.00843274,DB0023010029331_,4.775633542,-0.278131812,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,16075,DB00231,10029331,44,3252,39,2100,0.17402779,0.72860462,0.460873417,1.155714067,0.316189982,DB0023110029331_,1.151412038,-0.316624053,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,temazepam,DB00231
,16076,DB00316,10029331,646,64828,487,36466,1.60205136776312e-06,0.74617866,0.661861287,0.841637058,2.18412449178702e-05,DB0031610029331_,10.73171041,-0.292790217,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,16077,DB00327,10029331,64,6074,47,4215,0.771814325,0.944959764,0.63698034,1.410756103,0.875105771,DB0032710029331_,0.133410519,-0.05661293,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,16078,DB00338,10029331,405,33269,305,21967,0.089544524,0.876775781,0.753073112,1.021627208,0.194509559,DB0033810029331_,1.637273971,-0.131503986,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,16080,DB00451,10029331,544,46727,185,15234,0.634209379,0.958676764,0.809055313,1.140098282,0.77253718,DB0045110029331_,0.258075142,-0.042201316,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,16081,DB00695,10029331,301,27748,245,20283,0.222568891,0.898053996,0.75538173,1.06846702,0.376692528,DB0069510029331_,0.976326001,-0.107525083,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,16082,DB00829,10029331,80,7972,50,4404,0.519593598,0.88390648,0.61189189,1.287536562,0.678752465,DB0082910029331_,0.387498777,-0.123404013,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,16083,DB00904,10029331,379,22690,251,14205,0.508961161,0.945309938,0.802658763,1.11483059,0.669437756,DB0090410029331_,0.401317089,-0.056242429,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,16084,DB00996,10029331,600,38353,466,21959,1.22192623470917e-06,0.737213739,0.651319706,0.834793954,1.71206455646752e-05,DB0099610029331_,10.97522548,-0.304877417,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,16085,DB01015,10029331,129,9758,164,9217,0.013270248,0.742990644,0.584246275,0.943249698,0.044596109,DB0101510029331_,3.11010866,-0.297071826,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,16086,DB01069,10029331,72,6628,42,2353,0.013495734,0.608623918,0.409049348,0.915729194,0.045197855,DB0106910029331_,3.096705652,-0.496554743,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,16087,DB00188,10046571,140,7746,61,8767,1.26702000372766e-10,2.597461487,1.906612169,3.574549826,4.05400131442258e-09,DB0018810046571_,19.32356146,0.954534617,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,bortezomib,DB00188
,16088,DB00230,10046571,323,19351,71,8580,1.54594791936738e-08,2.017059652,1.553614304,2.649407056,3.32122934700217e-07,DB0023010046571_,14.91776065,0.701640833,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,pregabalin,DB00230
,16089,DB00231,10046571,89,3207,18,2121,5.99034141961937e-07,3.269470964,1.947736232,5.785478409,9.0962521210107e-06,DB0023110046571_,11.60764808,1.184628187,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,temazepam,DB00231
,16090,DB00316,10046571,1456,64018,408,36545,1.18729081046913e-40,2.037153044,1.822655053,2.280892002,4.80122137741246e-38,DB0031610046571_,85.92936319,0.711553267,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,16091,DB00327,10046571,100,6038,44,4218,0.010392841,1.587602343,1.100439755,2.32299442,0.036707315,DB0032710046571_,3.304779224,0.462224918,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,hydromorphone,DB00327
,16093,DB00497,10046571,326,18941,125,16250,1.51184777077371e-15,2.237357945,1.813029129,2.775178513,9.93472966369675e-14,DB0049710046571_,29.94015464,0.805295681,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,oxycodone,DB00497
,16094,DB00695,10046571,721,27328,268,20260,2.12330755455069e-23,1.994446373,1.729042924,2.306193307,2.94590944313565e-21,DB0069510046571_,47.27386937,0.690366504,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,16095,DB00829,10046571,193,7859,49,4405,2.00557733255246e-07,2.207573881,1.602171645,3.092459665,3.40216845344571e-06,DB0082910046571_,12.59109755,0.791894121,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,diazepam,DB00829
,16096,DB00904,10046571,600,22469,153,14303,3.18996670568149e-27,2.496270494,2.084186215,3.004792345,5.78263964543709e-25,DB0090410046571_,55.80976706,0.914797816,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ondansetron,DB00904
,16097,DB00996,10046571,880,38073,244,22181,2.89984347450107e-27,2.101122162,1.819444349,2.433481043,5.29322123105977e-25,DB0099610046571_,55.89820034,0.742471565,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,16098,DB01015,10046571,278,9609,121,9260,7.89593506224971e-14,2.213978014,1.778536462,2.769679674,4.10580657287382e-12,DB0101510046571_,26.21861891,0.794790904,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,16099,DB01069,10046571,156,6544,19,2376,5.48901146369824e-07,2.981047099,1.840802591,5.096319232,8.43241766939264e-06,DB0106910046571_,11.68342703,1.092274614,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,promethazine,DB01069
,16100,DB00188,10047700,164,7722,122,8706,0.000636795,1.515507248,1.189102128,1.935795591,0.003787343,DB0018810047700_,5.576090659,0.4157502,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,16101,DB00231,10047700,117,3179,30,2109,8.16679888963815e-07,2.586910912,1.712345851,4.019121149,1.19857235518782e-05,DB0023110047700_,11.33179432,0.950464466,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,temazepam,DB00231
,16102,DB00424,10047700,45,1149,14,414,0.763661477,1.158043678,0.616444635,2.309210542,0.869179957,DB0042410047700_,0.14020509,0.146732097,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,hyoscyamine,DB00424
,16103,DB00829,10047700,260,7792,86,4368,1.80235788366237e-05,1.694694609,1.319146143,2.194919876,0.000182246,DB0082910047700_,8.610150406,0.527502553,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,diazepam,DB00829
,16104,DB01015,10047700,348,9539,237,9144,6.38837525359744e-05,1.40752102,1.186842216,1.671448217,0.000542898,DB0101510047700_,7.518588552,0.341830015,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,16105,DB01069,10047700,493,6207,143,2252,0.022167069,1.250776068,1.029508571,1.526996693,0.067011631,DB0106910047700_,2.702889072,0.223764213,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,promethazine,DB01069
,16108,DB00327,10048294,86,6052,86,4176,0.018758808,0.690059502,0.50436107,0.944092375,0.058748393,DB0032710048294_,2.83449148,-0.370977451,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,hydromorphone,DB00327
,16110,DB00451,10048294,220,47051,102,15317,0.004215897,0.702150454,0.552315396,0.897583823,0.017825925,DB0045110048294_,4.02710141,-0.353607576,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,16111,DB00497,10048294,126,19141,135,16240,0.061635116,0.791886619,0.615651939,1.018016441,0.146451449,DB0049710048294_,1.921061309,-0.233337055,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,16112,DB00829,10048294,45,8007,44,4410,0.007523434,0.563283273,0.362771101,0.87521683,0.028365983,DB0082910048294_,3.562564629,-0.573972628,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,16113,DB00904,10048294,142,22927,134,14322,0.000772553,0.66200184,0.518594288,0.845407345,0.004442961,DB0090410048294_,5.416434271,-0.412486944,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,16114,DB01015,10048294,45,9842,68,9313,0.017908536,0.626215165,0.419378753,0.927133514,0.056660517,DB0101510048294_,2.870677662,-0.468061253,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,sulfamethoxazole,DB01015
,16115,DB01069,10048294,58,6642,15,2380,0.288133726,1.38544906,0.773208049,2.637543083,0.453142369,DB0106910048294_,0.791548922,0.326024318,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,promethazine,DB01069
,16119,DB00316,10063743,147,65327,76,36877,0.576737889,1.091868255,0.821994958,1.460351214,0.725945429,DB0031610063743_,0.320280434,0.087890225,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,16121,DB00338,10063743,78,33596,55,22217,0.723438368,0.937843674,0.65538989,1.35004177,0.837386203,DB0033810063743_,0.177469901,-0.064172002,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,16123,DB00451,10063743,101,47170,35,15384,0.765062279,0.941140835,0.634708223,1.425481348,0.870359749,DB0045110063743_,0.138848648,-0.060662486,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,16124,DB00497,10063743,49,19218,49,16326,0.419285134,0.849521739,0.559587947,1.289669022,0.588346666,DB0049710063743_,0.530438937,-0.163081748,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,16126,DB00904,10063743,102,22967,56,14400,0.461363691,1.14203682,0.815854013,1.6128973,0.628664915,DB0090410063743_,0.46415689,0.132813352,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,16127,DB00996,10063743,59,38894,38,22387,0.598747874,0.893683784,0.584365945,1.381522358,0.743572695,DB0099610063743_,0.296288744,-0.112403275,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,16128,DB01015,10063743,37,9850,30,9351,0.542619025,1.170842305,0.703189855,1.964108728,0.697836978,DB0101510063743_,0.359769759,0.157723409,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,sulfamethoxazole,DB01015
,16130,DB00112,10002855,86,5847,42,4049,0.070146629,1.417910859,0.967153765,2.107173155,0.161496379,DB0011210002855_,1.823272561,0.349184562,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,bevacizumab,DB00112
,16132,DB01101,10002855,54,7535,8,3900,0.000229502,3.493404021,1.650241969,8.511218577,0.001617502,DB0110110002855_,6.426872539,1.250876625,female,10002855,Anxiety,10037175,Psychiatric disorders,Psych,capecitabine,DB01101
,16133,DB00530,10011906,276,1532,293,975,5.30873784853264e-08,0.599621863,0.497161452,0.723001144,1.02162934513147e-06,DB0053010011906_,13.79411181,-0.511456051,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,erlotinib,DB00530
,16134,DB00112,10013968,289,5644,174,3917,0.160279626,1.152652927,0.947392756,1.405685099,0.297861281,DB0011210013968_,1.211127401,0.142066178,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bevacizumab,DB00112
,16135,DB00530,10013968,84,1724,57,1211,0.86146227,1.035161458,0.724490993,1.487910733,0.935200238,DB0053010013968_,0.066994615,0.034557412,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,erlotinib,DB00530
,16136,DB01101,10013968,186,7403,49,3859,1.0281388341137e-05,1.978613136,1.433640624,2.775913446,0.000111212,DB0110110013968_,9.104068077,0.682396163,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,capecitabine,DB01101
,16137,DB00530,10033371,55,1753,42,1226,0.676352373,0.915872126,0.597505475,1.41270312,0.80384645,DB0053010033371_,0.21834701,-0.087878525,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,erlotinib,DB00530
,16138,DB01101,10033371,216,7373,73,3835,0.001314585,1.538993622,1.17148375,2.041312313,0.006893432,DB0110110033371_,4.977186235,0.43112871,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,16142,DB00112,10061818,502,5431,331,3760,0.531484762,1.049989898,0.906330905,1.217544879,0.688316761,DB0011210061818_,0.373506139,0.048780544,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,16143,DB00530,10061818,178,1630,168,1100,0.003715436,0.715110741,0.567789065,0.900846509,0.016069146,DB0053010061818_,4.13085427,-0.335317865,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,erlotinib,DB00530
,16144,DB01101,10061818,645,6944,268,3640,0.001960471,1.261527244,1.086047716,1.468424509,0.00957914,DB0110110061818_,4.648167499,0.232323086,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,16148,DB00316,10054889,216,65258,156,36797,0.019980714,0.78076078,0.632235897,0.965933644,0.061711188,DB0031610054889_,2.785290029,-0.247486476,NA,10054889,Transaminases increased,10022891,Investigations,Inv,acetaminophen,DB00316
,16151,DB00073,10000081,118,7288,97,6310,0.730724376,1.05325936,0.796497727,1.395467148,0.843350648,DB0007310000081_,0.170372454,0.051889509,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,rituximab,DB00073
,16152,DB00531,10000081,122,7130,126,6390,0.275778552,0.867772021,0.669309289,1.124744053,0.439057495,DB0053110000081_,0.823124907,-0.141826247,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,16153,DB00541,10000081,101,3033,162,4135,0.227107874,0.850006601,0.653310683,1.10164007,0.382317654,DB0054110000081_,0.96150346,-0.162511163,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,vincristine,DB00541
,16154,DB00773,10000081,43,2280,61,2766,0.48624127,0.855203015,0.56266994,1.289840002,0.650136259,DB0077310000081_,0.430573308,-0.156416394,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,etoposide,DB00773
,16155,DB00987,10000081,65,2039,111,2817,0.186942985,0.809055253,0.583097082,1.114979999,0.332653851,DB0098710000081_,1.100652816,-0.211888066,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,cytarabine,DB00987
,16156,DB00997,10000081,138,5193,88,3426,0.83654311,1.034582276,0.783244786,1.372524119,0.915616725,DB0099710000081_,0.088157424,0.033997748,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,doxorubicin,DB00997
,16158,DB00316,10003598,80,65394,68,36885,0.016151316,0.663612407,0.474127725,0.931013659,0.052208983,DB0031610003598_,2.952500719,-0.410057024,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,16162,DB00635,10003598,58,32995,48,23746,0.491246138,0.869623574,0.582767246,1.303000512,0.654429745,DB0063510003598_,0.423991041,-0.139694835,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,16167,DB00073,10003988,150,7256,84,6323,0.001170403,1.556047811,1.180792027,2.062091022,0.006272616,DB0007310003988_,5.071561834,0.442149152,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,rituximab,DB00073
,16168,DB00531,10003988,129,7123,58,6458,5.87469841703085e-06,2.016388281,1.465245674,2.8038801,6.80248669126237e-05,DB0053110003988_,9.59563723,0.701307931,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclophosphamide,DB00531
,16169,DB00541,10003988,48,3086,29,4268,0.000432385,2.288896774,1.410670149,3.773565729,0.002734986,DB0054110003988_,5.901628848,0.828069943,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,vincristine,DB00541
,16170,DB00773,10003988,34,2289,27,2800,0.119679778,1.540228004,0.899061211,2.66290896,0.240908482,DB0077310003988_,1.423338159,0.43193046,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,etoposide,DB00773
,16171,DB00889,10003988,44,736,19,498,0.114753475,1.566416728,0.883443976,2.876516371,0.233260776,DB0088910003988_,1.455598241,0.448790672,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,granisetron,DB00889
,16173,DB00997,10003988,104,5227,31,3483,3.99717671040487e-05,2.235295877,1.480341791,3.462971587,0.000364369,DB0099710003988_,7.917343575,0.804373603,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,doxorubicin,DB00997
,16177,DB00073,10011906,365,7041,460,5947,2.76599975409786e-08,0.670218712,0.58002134,0.774019127,5.61663419559284e-07,DB0007310011906_,14.39236306,-0.400151184,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,16178,DB00515,10011906,131,1739,123,2028,0.104117231,1.241964538,0.955262087,1.615552536,0.217225972,DB0051510011906_,1.526817122,0.216694431,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cisplatin,DB00515
,16179,DB00541,10011906,64,3070,112,4185,0.122515296,0.778993127,0.561715702,1.072493075,0.245049238,DB0054110011906_,1.406296115,-0.249753056,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,vincristine,DB00541
,16180,DB00773,10011906,86,2237,98,2729,0.651690415,1.070527795,0.787451505,1.453233829,0.786053715,DB0077310011906_,0.24073015,0.068151793,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,etoposide,DB00773
,16181,DB00889,10011906,249,531,167,350,0.903361969,0.982787796,0.769505516,1.256621713,0.957387878,DB0088910011906_,0.043546663,-0.017362056,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,granisetron,DB00889
,16182,DB00987,10011906,31,2073,50,2878,0.570840348,0.86080548,0.529520644,1.379587015,0.721268016,DB0098710011906_,0.326744482,-0.149886723,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cytarabine,DB00987
,16183,DB00541,10013968,69,3065,86,4211,0.565686949,1.102298517,0.788343123,1.536581054,0.717238987,DB0054110013968_,0.332346178,0.09739756,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vincristine,DB00541
,16184,DB00635,10013968,1793,31260,1023,22771,8.40673591158515e-10,1.27671984,1.179394865,1.382622892,2.3722066928182e-08,DB0063510013968_,17.55686013,0.244294164,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,16185,DB00773,10013968,62,2261,92,2735,0.249696638,0.815226023,0.578076271,1.143157685,0.409207316,DB0077310013968_,0.893533366,-0.204289876,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etoposide,DB00773
,16186,DB00889,10013968,67,713,37,480,0.403723029,1.218875876,0.789570669,1.905960201,0.573397082,DB0088910013968_,0.556176814,0.197929021,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,granisetron,DB00889
,16187,DB00987,10013968,58,2046,61,2867,0.132426165,1.332261445,0.90939516,1.950039651,0.259143966,DB0098710013968_,1.350371518,0.286877833,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cytarabine,DB00987
,16188,DB00541,10016256,127,3007,162,4135,0.543880135,1.078018341,0.843585635,1.375212754,0.699014222,DB0054110016256_,0.358084191,0.075124487,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,vincristine,DB00541
,16189,DB00773,10016256,93,2230,94,2733,0.20362762,1.21247247,0.895248323,1.642003442,0.353418864,DB0077310016256_,1.040101343,0.192661638,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,etoposide,DB00773
,16190,DB00987,10016256,49,2055,77,2851,0.523186158,0.882906539,0.601300165,1.285761986,0.681565552,DB0098710016256_,0.383362844,-0.124535929,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cytarabine,DB00987
,16191,DB00073,10025197,54,7352,87,6320,0.000331097,0.533593796,0.372076909,0.759265382,0.002188579,DB0007310025197_,6.12450264,-0.62812041,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,rituximab,DB00073
,16192,DB00316,10025197,148,65326,78,36875,0.677485743,1.071063871,0.808514185,1.428197389,0.80448507,DB0031610025197_,0.217552871,0.068652426,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,16194,DB00531,10025197,32,7220,42,6474,0.128590471,0.683205922,0.416901361,1.109874355,0.253630025,DB0053110025197_,1.371878666,-0.380958968,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,cyclophosphamide,DB00531
,16195,DB00541,10025197,18,3116,39,4258,0.108156858,0.630728848,0.338933429,1.131631568,0.223296785,DB0054110025197_,1.499253517,-0.460879227,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,vincristine,DB00541
,16196,DB00635,10025197,129,32924,89,23705,0.783518726,1.043587891,0.790003248,1.383718392,0.882171087,DB0063510025197_,0.125369266,0.042664671,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,16200,DB00073,10028372,68,7338,60,6347,0.929225052,0.980273452,0.681311097,1.413448277,0.970793557,DB0007310028372_,0.029641442,-0.019923713,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,rituximab,DB00073
,16202,DB00531,10028372,61,7191,60,6456,0.648014369,0.91275848,0.627458642,1.328172123,0.783057084,DB0053110028372_,0.244549681,-0.091283968,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclophosphamide,DB00531
,16203,DB00541,10028372,30,3104,35,4262,0.53008139,1.176884203,0.696326023,1.977926665,0.687176433,DB0054110028372_,0.375164204,0.16287044,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,vincristine,DB00541
,16204,DB00635,10028372,298,32755,238,23556,0.235115623,0.900460393,0.756187089,1.073184962,0.392120437,DB0063510028372_,0.936186248,-0.104849099,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,16207,DB00987,10028372,31,2073,37,2891,0.53790795,1.168405695,0.698507482,1.94253788,0.693968316,DB0098710028372_,0.365328973,0.155640165,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,cytarabine,DB00987
,16208,DB00997,10028372,32,5299,25,3489,0.587387528,0.842806837,0.48299511,1.486197166,0.73446144,DB0099710028372_,0.308617783,-0.171017484,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,doxorubicin,DB00997
,16209,DB00073,10035598,47,7359,79,6328,0.000296969,0.51161602,0.348170983,0.744581552,0.002000728,DB0007310035598_,6.214244342,-0.670180897,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rituximab,DB00073
,16210,DB00316,10035598,338,65136,222,36731,0.085206697,0.858576842,0.722351751,1.022136821,0.187082947,DB0031610035598_,1.676203194,-0.152479095,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,16211,DB00515,10035598,38,1832,35,2116,0.345995506,1.253947767,0.767634155,2.053765879,0.515400067,DB0051510035598_,0.66281185,0.226296789,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cisplatin,DB00515
,16212,DB00531,10035598,110,7142,84,6432,0.27757511,1.179326605,0.877801986,1.589215924,0.44120325,DB0053110035598_,0.818249625,0.164943602,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclophosphamide,DB00531
,16213,DB00541,10035598,47,3087,71,4226,0.63922069,0.906205685,0.611262898,1.332787823,0.776285153,DB0054110035598_,0.253235361,-0.098488973,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vincristine,DB00541
,16214,DB00635,10035598,236,32817,207,23587,0.037703165,0.819444686,0.676469413,0.993191298,0.101017042,DB0063510035598_,2.29246604,-0.19912838,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,16215,DB00773,10035598,38,2285,53,2774,0.526171981,0.870446022,0.55612929,1.350854489,0.684082133,DB0077310035598_,0.379677291,-0.138749529,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etoposide,DB00773
,16217,DB00987,10035598,58,2046,53,2875,0.025391565,1.537576705,1.036300457,2.285523471,0.074355758,DB0098710035598_,2.598894165,0.430207609,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cytarabine,DB00987
,16218,DB00997,10035598,92,5239,51,3463,0.343784057,1.192348378,0.835414742,1.718323615,0.513036247,DB0099710035598_,0.667408779,0.175924789,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxorubicin,DB00997
,16229,DB00073,10046571,141,7265,72,6335,0.00022685,1.707575319,1.273876114,2.305576306,0.001602225,DB0007310046571_,6.436361887,0.535074422,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,rituximab,DB00073
,16230,DB00515,10046571,43,1827,35,2116,0.136429128,1.422772792,0.885228171,2.300838426,0.264691441,DB0051510046571_,1.329190506,0.352607638,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,cisplatin,DB00515
,16231,DB00531,10046571,94,7158,47,6469,0.000888149,1.807406121,1.258160753,2.627318094,0.004998927,DB0053110046571_,5.298531909,0.591892735,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,16233,DB00635,10046571,771,32282,229,23565,7.38141230925427e-37,2.457615104,2.115884759,2.863652939,2.53621467383985e-34,DB0063510046571_,77.35722048,0.89919141,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,16237,DB00997,10046571,56,5275,22,3492,0.036834411,1.68497112,1.010313139,2.903693513,0.099240723,DB0099710046571_,2.310206831,0.521748424,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,doxorubicin,DB00997
,16238,DB00073,10061818,102,7304,121,6286,0.017865453,0.725507426,0.550705163,0.954261624,0.056550268,DB0007310061818_,2.87262534,-0.320883971,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,16239,DB00316,10061818,626,64848,440,36513,0.000469691,0.801089181,0.7075036,0.907658745,0.002931111,DB0031610061818_,5.832373776,-0.221783001,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,16240,DB00515,10061818,58,1812,66,2085,1,1.011186621,0.693986654,1.469982741,1,DB0051510061818_,0,0.011124513,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,cisplatin,DB00515
,16241,DB00531,10061818,199,7053,135,6381,0.01069114,1.333595637,1.063496979,1.67646465,0.037551495,DB0053110061818_,3.282042078,0.287878781,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,16242,DB00541,10061818,65,3069,75,4222,0.301618937,1.192232924,0.838992614,1.690362077,0.467925029,DB0054110061818_,0.75944719,0.175827955,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,vincristine,DB00541
,16243,DB00773,10061818,50,2273,85,2742,0.065364,0.709656636,0.48783919,1.022999147,0.153066305,DB0077310061818_,1.876884083,-0.342974037,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,etoposide,DB00773
,16244,DB00889,10061818,69,711,53,464,0.437198612,0.849726653,0.57366239,1.264210341,0.605671448,DB0088910061818_,0.501417604,-0.162840566,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,granisetron,DB00889
,16245,DB00987,10061818,35,2069,70,2858,0.088777572,0.690721552,0.44482411,1.055299773,0.193212046,DB0098710061818_,1.643967008,-0.3700185,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,cytarabine,DB00987
,16246,DB00997,10061818,192,5139,80,3434,0.00040622,1.603652616,1.22455263,2.116295268,0.002596352,DB0099710061818_,5.953647871,0.472283913,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,16265,DB00999,10001053,45,21385,44,12195,0.014682409,0.583259394,0.376017095,0.905183219,0.048474173,DB0099910001053_,3.026724145,-0.539123261,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,16266,DB01015,10001053,53,9834,50,9331,1,1.005781908,0.669650667,1.512573592,1,DB0101510001053_,0,0.005765256,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,16269,DB01234,10001053,79,31546,74,32814,0.518676099,1.110476452,0.798089631,1.546574118,0.677890822,DB0123410001053_,0.388769033,0.104789159,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,16270,DB01409,10001053,62,5969,45,3921,0.620434757,0.905064389,0.605302395,1.362611829,0.760959712,DB0140910001053_,0.273174864,-0.09974919,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,16271,DB00188,10003658,89,7797,127,8701,0.086161723,0.782050782,0.588555585,1.035431465,0.188627902,DB0018810003658_,1.667978979,-0.245835601,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,bortezomib,DB00188
,16272,DB00196,10003658,34,5049,44,3241,0.002310998,0.496054746,0.306796371,0.795943294,0.01094201,DB0019610003658_,4.515145747,-0.701068983,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,fluconazole,DB00196
,16273,DB00787,10003658,173,16827,277,16971,1.89833006504121e-06,0.629905513,0.517255366,0.765372467,2.52884656908766e-05,DB0078710003658_,10.58516217,-0.46218545,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,acyclovir,DB00787
,16274,DB00868,10003658,33,2951,35,1611,0.007137969,0.514784622,0.308796434,0.856506701,0.02721519,DB0086810003658_,3.603980018,-0.664006675,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,benzonatate,DB00868
,16275,DB00999,10003658,183,21247,165,12074,2.46201850144983e-05,0.630240119,0.50724161,0.78361342,0.000238402,DB0099910003658_,8.341553263,-0.461654391,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,16276,DB01015,10003658,73,9814,119,9262,0.000265278,0.578962363,0.425917421,0.78245631,0.001825348,DB0101510003658_,6.305984776,-0.546517807,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,sulfamethoxazole,DB01015
,16279,DB01234,10003658,349,31276,501,32387,3.00146987335191e-06,0.721358216,0.626818625,0.829374684,3.79205170012281e-05,DB0123410003658_,10.18001825,-0.326619432,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,16280,DB01409,10003658,82,5949,64,3902,0.307358845,0.840402805,0.597065236,1.187393199,0.474477432,DB0140910003658_,0.745541223,-0.173873973,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,tiotropium,DB01409
,16283,DB00588,10009033,320,16204,163,8305,1,1.006189288,0.82903729,1.224929063,1,DB0058810009033_,0,0.006170213,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,16284,DB00787,10009033,32,16968,59,17189,0.006158562,0.549449572,0.345510256,0.859392291,0.02416451,DB0078710009033_,3.722870256,-0.59883828,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,16285,DB00868,10009033,54,2930,24,1622,0.405601174,1.245544589,0.753576802,2.115133413,0.575178812,DB0086810009033_,0.55307431,0.219572855,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,benzonatate,DB00868
,16286,DB00999,10009033,112,21318,52,12187,0.223317619,1.231338239,0.87783852,1.746866271,0.37764362,DB0099910009033_,0.973804333,0.208101577,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,16290,DB01234,10009033,74,31551,110,32778,0.01800126,0.698895807,0.513134107,0.94735385,0.056858312,DB0123410009033_,2.867192862,-0.358253608,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,16291,DB01409,10009033,366,5665,230,3736,0.604472187,1.049447855,0.882719594,1.249563773,0.74780211,DB0140910009033_,0.290616895,0.048264173,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,16292,DB00196,10035664,195,4888,173,3112,0.00219778,0.717670338,0.578844924,0.890366126,0.010503389,DB0019610035664_,4.55605735,-0.331744954,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,fluconazole,DB00196
,16293,DB00588,10035664,890,15634,496,7972,0.128924106,0.914972583,0.816116055,1.026659118,0.254040266,DB0058810035664_,1.370262498,-0.088861178,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,16294,DB00787,10035664,941,16059,1236,16012,6.15317701115154e-10,0.759107744,0.694678894,0.829292208,1.77537055694971e-08,DB0078710035664_,17.84667158,-0.275611556,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,acyclovir,DB00787
,16295,DB00868,10035664,267,2717,179,1467,0.037305878,0.805428513,0.656736531,0.989390047,0.100192602,DB0086810035664_,2.300660925,-0.216380829,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,benzonatate,DB00868
,16296,DB00999,10035664,546,20884,350,11889,0.091086947,0.888094971,0.773614178,1.020540728,0.196990325,DB0099910035664_,1.624600663,-0.118676592,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,16297,DB01015,10035664,383,9504,520,8861,4.54650429065498e-08,0.686725991,0.598280968,0.787678732,8.8489348596717e-07,DB0101510035664_,13.93779855,-0.375819915,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,16299,DB01042,10035664,32,958,59,1269,0.159777685,0.718546527,0.448239895,1.133447183,0.297163362,DB0104210035664_,1.213473253,-0.33052482,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,melphalan,DB01042
,16300,DB01409,10035664,416,5615,302,3664,0.178363065,0.898871462,0.768590773,1.052111677,0.32178683,DB0140910035664_,1.133865972,-0.106615234,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,tiotropium,DB01409
,16301,DB00188,10038435,96,7790,134,8694,0.096882561,0.7995672,0.607574183,1.04891441,0.206098909,DB0018810038435_,1.579399084,-0.223684698,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,bortezomib,DB00188
,16302,DB00196,10038435,47,5036,40,3245,0.224608623,0.757162365,0.484837195,1.187419873,0.379289946,DB0019610038435_,0.969454337,-0.278177564,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,fluconazole,DB00196
,16303,DB00787,10038435,165,16835,210,17038,0.029169011,0.795195622,0.643798934,0.980862027,0.082864497,DB0078710038435_,2.490548577,-0.229167129,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,acyclovir,DB00787
,16305,DB00999,10038435,151,21279,125,12114,0.002498274,0.687742123,0.538386126,0.879724477,0.011652942,DB0099910038435_,4.452196583,-0.374341333,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,hydrochlorothiazide,DB00999
,16306,DB01015,10038435,93,9794,132,9249,0.00307787,0.665358732,0.503903191,0.875558614,0.013822281,DB0101510038435_,4.281473457,-0.407428937,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,sulfamethoxazole,DB01015
,16309,DB01409,10038435,45,5986,29,3937,1,1.020569923,0.624836832,1.69115293,1,DB0140910038435_,0,0.020361219,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,tiotropium,DB01409
,16312,DB11089,10051055,100,10075,107,8300,0.067725028,0.769942284,0.579360503,1.022479411,0.15723644,DB1108910051055_,1.850004619,-0.261439723,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,docusate,DB11089
,16315,DB00285,10024264,34,10917,34,3684,1.54671568774473e-05,0.337490453,0.203225871,0.560473771,0.000159121,DB0028510024264_,8.745845483,-1.086218056,male,10024264,Lethargy,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,16316,DB00285,10043071,60,10891,19,3699,0.89696575,1.07253641,0.630235692,1.905742375,0.956338178,DB0028510043071_,0.044643686,0.07002632,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,venlafaxine,DB00285
,16318,DB00331,10007554,51,24895,76,20676,0.001244522,0.557342783,0.382809783,0.805576152,0.006587911,DB0033110007554_,5.022519032,-0.584574819,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,metformin,DB00331
,16321,DB00331,10040047,234,24712,257,20495,0.002234383,0.755141779,0.629246887,0.905866047,0.010648312,DB0033110040047_,4.54235386,-0.28084976,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,metformin,DB00331
,16323,DB00544,10011906,225,2210,225,2428,0.348035219,1.098621647,0.900861933,1.339798476,0.517575752,DB0054410011906_,0.658599383,0.094056346,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,fluorouracil,DB00544
,16327,DB00112,10053762,1292,4641,986,3105,0.006609863,0.876683321,0.796754334,0.964775568,0.025589548,DB0011210053762_,3.665571279,-0.131609445,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,bevacizumab,DB00112
,16328,DB00544,10053762,180,2255,182,2471,0.478132323,1.083718165,0.869899508,1.350047221,0.643441947,DB0054410053762_,0.440923471,0.080397874,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,fluorouracil,DB00544
,16331,DB01229,10020772,155,5586,21,2688,4.72038717253412e-10,3.551280855,2.237304183,5.914821705,1.3909795608751e-08,DB0122910020772_,18.09067252,1.267308343,female,10020772,Hypertension,10047065,Vascular disorders,Vasc,paclitaxel,DB01229
,16332,DB00112,10027452,68,5865,26,4065,0.010990935,1.812602925,1.135900494,2.973572574,0.03839159,DB0011210027452_,3.259916858,0.594763892,NA,10027452,Metastases to bone,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,bevacizumab,DB00112
,16333,DB01229,10027452,71,5670,11,2698,0.000181635,3.070998227,1.613479467,6.439124953,0.00132988,DB0122910027452_,6.622666408,1.122002664,female,10027452,Metastases to bone,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,paclitaxel,DB01229
,16334,DB00112,10027458,52,5881,21,4070,0.041585755,1.71357986,1.012596142,3.000032318,0.108910633,DB0011210027458_,2.217227617,0.538584668,NA,10027458,Metastases to lung,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,bevacizumab,DB00112
,16345,DB01229,10053762,365,5376,122,2587,0.000550713,1.439635584,1.163079421,1.791683458,0.003341909,DB0122910053762_,5.701213112,0.364390015,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,paclitaxel,DB01229
,16351,DB00531,10003239,94,7158,46,6470,0.000619087,1.846980508,1.282552058,2.692964806,0.003696395,DB0053110003239_,5.600397153,0.613552148,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclophosphamide,DB00531
,16352,DB00541,10003239,30,3104,21,4276,0.021881837,1.967815759,1.087367171,3.623948954,0.066351052,DB0054110003239_,2.712795668,0.676924176,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,vincristine,DB00541
,16353,DB00997,10003239,77,5254,14,3500,7.15401068485752e-07,3.663422872,2.052564588,7.023593782,1.0647971169393e-05,DB0099710003239_,11.45014118,1.298397921,female,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,doxorubicin,DB00997
,16354,DB00541,10028813,149,2985,209,4088,0.869331382,0.976353351,0.781673128,1.217180309,0.941838249,DB0054110028813_,0.059921729,-0.023930718,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,vincristine,DB00541
,16355,DB00073,10029331,54,7352,100,6307,4.25307555291399e-06,0.463267511,0.32577064,0.652585839,5.12103027523336e-05,DB0007310029331_,9.879569821,-0.769450614,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,rituximab,DB00073
,16356,DB00541,10029331,71,3063,115,4182,0.292539265,0.842966052,0.615688936,1.147466209,0.458135458,DB0054110029331_,0.780590378,-0.170828593,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,vincristine,DB00541
,16357,DB00635,10029331,258,32795,217,23577,0.092753549,0.854758869,0.710218069,1.029492537,0.199633738,DB0063510029331_,1.611270899,-0.156935875,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,16358,DB00997,10029331,140,5191,80,3434,0.328832368,1.157621049,0.870239527,1.548828099,0.497465311,DB0099710029331_,0.698229451,0.146367079,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,doxorubicin,DB00997
,16362,DB00635,10040742,66,32987,22,23772,0.001119016,2.161898461,1.31643797,3.68049023,0.00604156,DB0063510040742_,5.109093085,0.770986753,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,16364,DB00073,10046306,35,7371,31,6376,1,0.97662185,0.584179441,1.639826751,1,DB0007310046306_,0,-0.023655754,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,rituximab,DB00073
,16365,DB00531,10046306,39,7213,46,6470,0.231019927,0.760511687,0.48270625,1.192834365,0.387169012,DB0053110046306_,0.948893958,-0.273763799,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,16366,DB00541,10046306,15,3119,40,4257,0.027783381,0.511868735,0.262175975,0.949056544,0.079747331,DB0054110046306_,2.528892011,-0.669687064,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,vincristine,DB00541
,16367,DB00635,10046306,353,32700,122,23672,1.95473203292688e-13,2.094562616,1.698988048,2.596804758,9.66700498315768e-12,DB0063510046306_,25.36230258,0.739344757,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,16369,DB00073,10065553,46,7360,39,6368,1,1.020513494,0.650642017,1.60791769,1,DB0007310065553_,0,0.020305926,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,rituximab,DB00073
,16370,DB00531,10065553,95,7157,76,6440,0.488113265,1.124755833,0.821467059,1.544373054,0.651701995,DB0053110065553_,0.428167884,0.117565974,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,cyclophosphamide,DB00531
,16371,DB00541,10065553,58,3076,64,4233,0.230724532,1.247078286,0.856051613,1.813525418,0.386760265,DB0054110065553_,0.949950249,0.220803445,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,vincristine,DB00541
,16372,DB00635,10065553,74,32979,86,23708,0.002873928,0.618591892,0.446884419,0.854421154,0.013053934,DB0063510065553_,4.338665759,-0.480309526,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,16373,DB00997,10065553,82,5249,57,3457,0.793406511,0.947480019,0.665588172,1.356682404,0.887962622,DB0099710065553_,0.118825629,-0.053949431,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,doxorubicin,DB00997
,16374,DB00186,10002855,533,16368,237,9771,0.000176901,1.34251031,1.147400727,1.574460038,0.001299386,DB0018610002855_,6.645863541,0.294541227,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,16375,DB00490,10002855,184,3886,78,1498,0.481582673,0.90937296,0.689126882,1.209113514,0.646196343,DB0049010002855_,0.436651885,-0.094999971,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,buspirone,DB00490
,16376,DB00656,10002855,362,11651,136,6483,9.58157307720419e-05,1.481063766,1.209817843,1.821700846,0.000768263,DB0065610002855_,7.171377897,0.392760591,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,16377,DB00678,10002855,215,15384,96,10628,0.000312456,1.547184377,1.209186631,1.991705419,0.002086974,DB0067810002855_,6.172040248,0.436436748,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,losartan,DB00678
,16378,DB00736,10002855,214,10377,67,5486,0.000136069,1.688534481,1.275018385,2.260852767,0.001037137,DB0073610002855_,6.871291227,0.523860982,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,esomeprazole,DB00736
,16379,DB01233,10002855,80,3341,17,1709,0.000478135,2.406823568,1.407891479,4.349037695,0.002977345,DB0123310002855_,5.816723298,0.878307857,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,metoclopramide,DB01233
,16381,DB00285,10000081,142,10809,39,3679,0.263848998,1.239249757,0.862225042,1.818436055,0.425711798,DB0028510000081_,0.853992692,0.214506162,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,16382,DB00924,10000081,159,10003,42,4209,0.006347604,1.592887409,1.125070932,2.299337032,0.024776771,DB0092410000081_,3.697848707,0.46554835,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,16388,DB00285,10012378,418,10533,126,3592,0.248063758,1.131320033,0.921347852,1.397006304,0.407443738,DB0028510012378_,0.897852423,0.123385121,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,16389,DB00924,10012378,253,9909,54,4197,1.78717030705679e-06,1.984349462,1.470511525,2.720112886,2.39733460173452e-05,DB0092410012378_,10.63856793,0.685291133,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,16394,DB00285,10027599,115,10836,9,3709,3.65438749437392e-07,4.373467918,2.222051235,9.81714359,5.83003471560132e-06,DB0028510027599_,12.0524876,1.475556268,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,16395,DB00316,10027599,653,64821,101,36852,1.08486352344299e-44,3.675631346,2.975215441,4.580786648,5.09207816316055e-42,DB0031610027599_,95.08088787,1.301724913,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,16396,DB00924,10027599,122,10040,16,4235,7.33504466820089e-07,3.215870068,1.899892399,5.811291082,1.08867805210577e-05,DB0092410027599_,11.4279613,1.168097949,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,16397,DB00783,10028813,1005,15709,13,360,0.045369496,1.77168649,1.018058827,3.371968469,0.116288367,DB0078310028813_,2.151682251,0.571931912,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,estradiol,DB00783
,16398,DB00924,10028813,650,9512,156,4095,1.94955131446867e-11,1.793721797,1.497780344,2.158454249,7.08768413565823e-10,DB0092410028813_,21.06749228,0.584292677,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,16399,DB00285,10030095,39,10912,13,3705,1,1.018607701,0.531539786,2.082135725,1,DB0028510030095_,0,0.018436696,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,16400,DB00924,10030095,63,10099,17,4234,0.111087817,1.553673248,0.89665037,2.835766642,0.227718712,DB0092410030095_,1.479644132,0.440621965,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,16401,DB00924,10037377,61,10101,39,4212,0.046876108,0.652233607,0.428602001,1.003027595,0.119217913,DB0092410037377_,2.126802255,-0.427352488,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,16402,DB00783,10047700,408,16306,6,367,0.393151973,1.530456996,0.690400135,4.222695561,0.563072891,DB0078310047700_,0.574346191,0.425566381,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,estradiol,DB00783
,16403,DB00924,10047700,328,9834,78,4173,1.88972013612587e-06,1.784358012,1.386073493,2.320771297,2.51818979863465e-05,DB0092410047700_,10.58938516,0.579058693,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,16404,DB00285,10047924,43,10908,7,3711,0.072721871,2.089884509,0.930957756,5.511430094,0.166065277,DB0028510047924_,1.795374333,0.737108806,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,venlafaxine,DB00285
,16405,DB00316,10047924,228,65246,104,36849,0.075911381,1.238189848,0.977275267,1.577353229,0.171346557,DB0031610047924_,1.764067126,0.213650513,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,16407,DB00924,10047924,55,10107,13,4238,0.062437017,1.773956103,0.95554073,3.54334356,0.147998647,DB0092410047924_,1.910552146,0.573212139,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,16413,DB00316,10071406,37,65437,13,36940,0.184138069,1.60668165,0.834562539,3.294319951,0.329077315,DB0031610071406_,1.111462557,0.474170965,NA,10071406,Maternal exposure before pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,16418,DB00112,10048294,30,5903,33,4058,0.071385607,0.624998315,0.367566382,1.058894938,0.163675043,DB0011210048294_,1.809872264,-0.470006326,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,bevacizumab,DB00112
,16420,DB00958,10048294,33,4561,23,2562,0.484896633,0.805982305,0.458037785,1.440909376,0.649039236,DB0095810048294_,0.432262109,-0.215693491,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,carboplatin,DB00958
,16423,DB00112,10059282,39,5894,12,4079,0.01435785,2.249016698,1.151936148,4.724854847,0.047560944,DB0011210059282_,3.045743367,0.810493097,NA,10059282,Metastases to central nervous system,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,bevacizumab,DB00112
,16428,DB00958,10061818,209,4385,108,2477,0.473403087,1.093147253,0.857732182,1.399539189,0.639336183,DB0095810061818_,0.447324854,0.089060924,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,16429,DB01248,10061818,173,2527,93,1281,0.687419303,0.943004302,0.72190521,1.238034236,0.811574878,DB0124810061818_,0.208778625,-0.058684434,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,16436,DB00441,10011906,409,1865,257,1637,0.000110144,1.396765427,1.175321875,1.662125947,0.000866159,DB0044110011906_,7.051442394,0.334159154,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,gemcitabine,DB00441
,16442,DB00441,10053762,326,1948,263,1631,0.687979453,1.037831267,0.867817517,1.241958263,0.81188587,DB0044110053762_,0.208395503,0.037133216,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,gemcitabine,DB00441
,16443,DB00530,10053762,111,1697,138,1130,3.14105747020082e-06,0.535699716,0.408653134,0.701012347,3.94094012430685e-05,DB0053010053762_,10.14150616,-0.624181507,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,erlotinib,DB00530
,16444,DB01234,10053762,865,30760,862,32026,0.379802462,1.04479631,0.948382488,1.150999688,0.549912291,DB0123410053762_,0.597996485,0.043821948,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,16448,DB00441,10061818,176,2098,100,1794,0.001412669,1.504826579,1.160712912,1.959312844,0.007311607,DB0044110061818_,4.918292147,0.408677662,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,gemcitabine,DB00441
,16453,DB00958,10033371,155,4439,73,2512,0.207792529,1.20156655,0.899830732,1.616706251,0.358634665,DB0095810033371_,1.025451056,0.183626164,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,16454,DB01101,10053762,285,7304,222,3686,3.07131041958329e-06,0.647874418,0.539212692,0.77922122,3.86912985280358e-05,DB0110110053762_,10.15989583,-0.434058401,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,capecitabine,DB01101
,16455,DB00112,10055798,53,5880,39,4052,0.750544322,0.936497054,0.606447468,1.457437444,0.858974072,DB0011210055798_,0.152016541,-0.065608903,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,bevacizumab,DB00112
,16462,DB01229,10059282,42,5699,23,2686,0.594092662,0.860679976,0.504713718,1.502549595,0.740127997,DB0122910059282_,0.300932139,-0.150032532,NA,10059282,Metastases to central nervous system,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,paclitaxel,DB01229
,16465,DB00073,10000059,72,7334,36,6371,0.006547855,1.737314994,1.147214643,2.673031585,0.025388755,DB0007310000059_,3.67344891,0.552340814,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,rituximab,DB00073
,16467,DB00433,10000059,97,7559,51,5969,0.019608582,1.50184636,1.057366146,2.155239995,0.060860026,DB0043310000059_,2.799178708,0.406695258,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,16468,DB00635,10000059,370,32683,165,23629,1.45790598937701e-07,1.621200089,1.344739256,1.961300326,2.55644155642259e-06,DB0063510000059_,12.87689428,0.483166671,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,16469,DB00695,10000059,357,27692,178,20350,2.27895181816046e-05,1.473853825,1.226634932,1.775985022,0.000223403,DB0069510000059_,8.406532766,0.38788062,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,16470,DB00813,10000059,68,10504,25,10143,1.5657479121199e-05,2.626600677,1.637243144,4.340101153,0.000160764,DB0081310000059_,8.73557068,0.965690492,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,16471,DB01050,10000059,283,17825,102,9269,0.001379181,1.442726876,1.144812239,1.830129827,0.007176437,DB0105010000059_,4.936952293,0.366534987,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,16481,DB00099,10016256,187,2198,127,1828,0.099078833,1.22451992,0.963575074,1.560047494,0.209457284,DB0009910016256_,1.563235457,0.202548865,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,filgrastim,DB00099
,16483,DB00073,10019974,59,7347,36,6371,0.09949861,1.421134577,0.921983013,2.217985026,0.210099692,DB0007310019974_,1.560173137,0.351455551,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,rituximab,DB00073
,16485,DB00433,10019974,30,7626,22,5998,0.888994439,1.072539692,0.597614619,1.953488655,0.953939248,DB0043310019974_,0.047155291,0.07002938,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,16486,DB00682,10019974,89,19370,40,16324,0.000734295,1.875053733,1.276581203,2.797327972,0.004255527,DB0068210019974_,5.459536721,0.628637317,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,warfarin,DB00682
,16487,DB00695,10019974,126,27923,65,20463,0.022728924,1.420564377,1.044349159,1.948105888,0.068258185,DB0069510019974_,2.68445793,0.351054241,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,furosemide,DB00695
,16489,DB01050,10019974,78,18030,22,9349,0.010863251,1.838368553,1.132351358,3.101612375,0.038039107,DB0105010019974_,3.269140526,0.608878523,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,16502,DB00682,10025197,39,19420,19,16345,0.048809718,1.727583883,0.974142478,3.166579394,0.122793302,DB0068210025197_,2.097252811,0.546723833,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,warfarin,DB00682
,16503,DB00695,10025197,58,27991,33,20495,0.288194558,1.286888981,0.825020111,2.037913807,0.453197366,DB0069510025197_,0.791427562,0.252227663,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,furosemide,DB00695
,16505,DB01050,10025197,45,18063,20,9351,0.603299029,1.164777317,0.673381098,2.083648962,0.746988853,DB0105010025197_,0.291705016,0.152529925,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,ibuprofen,DB01050
,16506,DB00073,10030095,39,7367,18,6389,0.032324428,1.878945181,1.048361939,3.492964357,0.089795772,DB0007310030095_,2.410217388,0.630710546,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,16508,DB00433,10030095,53,7603,25,5995,0.038921917,1.67156636,1.01923207,2.810677935,0.103470301,DB0043310030095_,2.268470655,0.513761127,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,16509,DB00635,10030095,249,32804,131,23663,0.003445062,1.371097483,1.104510197,1.708502708,0.015130067,DB0063510030095_,4.191071354,0.315611502,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,16510,DB00813,10030095,45,10527,17,10151,0.000796909,2.5525966,1.431391101,4.760161619,0.004559587,DB0081310030095_,5.390523262,0.937111116,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,16511,DB01050,10030095,57,18051,17,9354,0.04888329,1.737456777,0.995671403,3.188088967,0.122891996,DB0105010030095_,2.096449389,0.552422422,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,16521,DB00073,10043554,116,7290,198,6209,2.71358150843564e-09,0.499015048,0.392318103,0.632366299,6.91483179343003e-08,DB0007310043554_,16.4870121,-0.695119027,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,rituximab,DB00073
,16522,DB00433,10043554,154,7502,109,5911,0.415224575,1.113170246,0.863196112,1.439704178,0.584474146,DB0043310043554_,0.537042732,0.107212022,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,prochlorperazine,DB00433
,16523,DB00682,10043554,114,19345,122,16242,0.066421701,0.784550601,0.60181501,1.022099572,0.154922083,DB0068210043554_,1.86483298,-0.242644208,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,warfarin,DB00682
,16524,DB00695,10043554,201,27848,219,20309,4.53860810523758e-05,0.669357681,0.549455962,0.815017139,0.000406742,DB0069510043554_,7.80733244,-0.401436711,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,furosemide,DB00695
,16525,DB01050,10043554,90,18018,65,9306,0.041542889,0.715112157,0.513510977,1.00066349,0.108830899,DB0105010043554_,2.217959983,-0.335315886,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,ibuprofen,DB01050
,16526,DB00073,10047895,102,7304,114,6293,0.063229356,0.770908492,0.583029928,1.018207062,0.149351512,DB0007310047895_,1.901452611,-0.2601856,NA,10047895,Weight decreased,10022891,Investigations,Inv,rituximab,DB00073
,16527,DB00099,10047895,68,2317,52,1903,0.711085515,1.074039775,0.733498763,1.580464288,0.827730988,DB0009910047895_,0.189067072,0.07142703,NA,10047895,Weight decreased,10022891,Investigations,Inv,filgrastim,DB00099
,16528,DB00433,10047895,202,7454,163,5857,0.83078218,0.973747585,0.785939215,1.207942495,0.911436604,DB0043310047895_,0.092733238,-0.026603162,NA,10047895,Weight decreased,10022891,Investigations,Inv,prochlorperazine,DB00433
,16529,DB00813,10047895,178,10394,128,10040,0.011261107,1.34323976,1.06242098,1.702157014,0.039126321,DB0081310047895_,3.24095988,0.295084427,NA,10047895,Weight decreased,10022891,Investigations,Inv,fentanyl,DB00813
,16530,DB01050,10047895,296,17812,171,9200,0.257537787,0.894075885,0.736845532,1.087556632,0.418431249,DB0105010047895_,0.871242683,-0.111964624,NA,10047895,Weight decreased,10022891,Investigations,Inv,ibuprofen,DB01050
,16540,DB00099,10061428,69,2316,37,1918,0.037671755,1.544237766,1.016159667,2.379920378,0.100958613,DB0009910061428_,2.293044617,0.434530433,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,filgrastim,DB00099
,16541,DB00433,10061428,220,7436,193,5827,0.268338796,0.89325433,0.730569091,1.092892689,0.430839223,DB0043310061428_,0.842020291,-0.112883934,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,prochlorperazine,DB00433
,16542,DB00682,10061428,391,19068,276,16088,0.025300707,1.195259358,1.020437988,1.401538817,0.074164057,DB0068210061428_,2.601475659,0.178363198,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,16543,DB00813,10061428,167,10405,94,10074,2.12494124981211e-05,1.720025779,1.325917155,2.24235438,0.000210294,DB0081310061428_,8.467004107,0.542339278,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,fentanyl,DB00813
,16544,DB01050,10061428,265,17843,138,9233,0.957811073,0.993668023,0.804554413,1.231637209,0.995494822,DB0105010061428_,0.004515357,-0.006352109,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ibuprofen,DB01050
,16546,DB00073,10061819,35,7371,29,6378,0.900539457,1.044313137,0.619338392,1.773341477,0.956698706,DB0007310061819_,0.044266769,0.043359384,NA,10061819,Disease recurrence,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,16549,DB00635,10061819,74,32979,80,23714,0.013875383,0.665151929,0.477986885,0.924506993,0.046224897,DB0063510061819_,3.074236734,-0.4077398,NA,10061819,Disease recurrence,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,16561,DB00099,10000081,51,2334,42,1913,1,0.995257264,0.645453858,1.541956503,1,DB0009910000081_,0,-0.004754018,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,filgrastim,DB00099
,16564,DB00316,10002511,50,65424,8,36945,0.000288091,3.529340541,1.659986988,8.621330336,0.001951419,DB0031610002511_,6.239198561,1.261111038,female,10002511,Anhedonia,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,16568,DB00316,10012575,44,65430,8,36945,0.001325313,3.105534439,1.445916891,7.637177395,0.006945637,DB0031610012575_,4.969641589,1.133185823,female,10012575,Device breakage,10077536,Product issues,Prod,acetaminophen,DB00316
,16572,DB00316,10022116,378,65096,55,36898,6.46900540735487e-28,3.895583697,2.929008889,5.269535057,1.25027799362002e-25,DB0031610022116_,57.3412614,1.359843526,female,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,16575,DB00316,10039580,77,65397,24,36929,0.009408373,1.811701168,1.13273821,2.997272548,0.033899805,DB0031610039580_,3.384346025,0.594266276,NA,10039580,Scar,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,16582,DB00316,10049119,231,65243,42,36911,3.54741159437499e-14,3.11156886,2.23131814,4.433778036,1.93201506234682e-12,DB0031610049119_,26.97245758,1.135127055,female,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,16585,DB00316,10064684,135,65339,16,36937,1.48922357457382e-12,4.769310471,2.832143471,8.584381707,6.50236572386592e-11,DB0031610064684_,23.45626995,1.562201739,female,10064684,Device dislocation,10077536,Product issues,Prod,acetaminophen,DB00316
,16588,DB00316,10064882,93,65381,32,36921,0.015151196,1.641166761,1.087382812,2.535907701,0.049709692,DB0031610064882_,3.00155535,0.495407429,NA,10064882,Procedural pain,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,16598,DB09153,10001053,62,7737,45,5654,1,1.006844106,0.673797555,1.514906816,1,DB0915310001053_,0,0.006820791,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,16603,DB14513,10002034,136,7041,51,3513,0.08523252,1.330485457,0.955011828,1.878452737,0.187123557,DB1451310002034_,1.675986149,0.285543881,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,magnesium,DB14513
,16605,DB00351,10012174,30,636,45,819,0.552551368,0.858575909,0.515902314,1.41104591,0.706384966,DB0035110012174_,0.347594913,-0.152480182,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,megestrol acetate,DB00351
,16608,DB09153,10012174,114,7685,109,5590,0.047254137,0.760781564,0.578557145,1.000834761,0.119931926,DB0915310012174_,2.120830982,-0.273409,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,sodium chloride,DB09153
,16609,DB14513,10012174,115,7062,56,3508,0.934930562,1.02009604,0.732913724,1.434053624,0.975242567,DB1451310012174_,0.025069052,0.01989678,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,magnesium,DB14513
,16611,DB00316,10040070,184,65290,143,36810,0.004645744,0.725465492,0.579676379,0.909410878,0.019269903,DB0031610040070_,3.949210835,-0.320941773,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,16615,DB09153,10040070,43,7756,43,5656,0.154896822,0.72926915,0.465896714,1.141479991,0.290667301,DB0915310040070_,1.235575961,-0.315712411,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,16618,DB00316,10045170,23,65451,37,36916,6.85062781919034e-05,0.350613289,0.198869277,0.605957403,0.000576128,DB0031610045170_,7.459181001,-1.048071403,male,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,16624,DB00257,10046571,41,911,10,612,0.003215838,2.752770072,1.343322262,6.210721582,0.014313486,DB0025710046571_,4.246553142,1.012607704,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,clotrimazole,DB00257
,16627,DB09104,10046571,51,999,25,847,0.025897473,1.729130526,1.04145902,2.939051969,0.075471488,DB0910410046571_,2.584000338,0.547618696,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,magnesium hydroxide,DB09104
,16628,DB14513,10046571,183,6994,50,3514,0.000100287,1.838802554,1.334440377,2.574079657,0.000799648,DB1451310046571_,7.131338479,0.609114574,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,magnesium,DB14513
,16629,DB00264,10016326,59,29548,32,24860,0.045655169,1.551209878,0.991980857,2.466354259,0.116821234,DB0026410016326_,2.147110425,0.439035193,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,16632,DB00695,10016326,67,27982,25,20503,0.003030654,1.963653915,1.223337553,3.246182737,0.013630036,DB0069510016326_,4.295479388,0.67480698,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,16637,DB00264,10016334,78,29529,63,24829,0.865686558,1.04103991,0.736999974,1.475509421,0.938991094,DB0026410016334_,0.062949284,0.040220127,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,16639,DB00695,10016334,105,27944,28,20500,3.59368015692176e-07,2.750929248,1.797855665,4.338452244,5.74573497108811e-06,DB0069510016334_,12.06705272,1.011938763,female,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,16640,DB00787,10016334,39,16961,23,17225,0.041604469,1.722006978,1.002706624,3.021691626,0.108937937,DB0078710016334_,2.216976946,0.543490458,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,16644,DB00787,10028813,794,16206,425,16823,1.54175057099255e-28,1.939311339,1.718127595,2.191299922,3.09350486706406e-26,DB0078710028813_,58.73790771,0.66233293,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,16645,DB01254,10028813,321,3146,166,2982,4.09103814553304e-10,1.83275444,1.50443078,2.239234,1.21850354283667e-08,DB0125410028813_,18.22305724,0.605819994,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dasatinib,DB01254
,16646,DB00285,10047895,162,10789,55,3663,1,1,0.730393534,1.387095929,1,DB0028510047895_,0,0,NA,10047895,Weight decreased,10022891,Investigations,Inv,venlafaxine,DB00285
,16647,DB00787,10047895,270,16730,298,16950,0.330469802,0.917976018,0.774559055,1.087484991,0.499175286,DB0078710047895_,0.694797971,-0.085584013,NA,10047895,Weight decreased,10022891,Investigations,Inv,acyclovir,DB00787
,16648,DB01015,10047895,159,9728,152,9229,0.954455842,0.992394997,0.788032297,1.250116968,0.992309296,DB0101510047895_,0.00772043,-0.007634068,NA,10047895,Weight decreased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,16649,DB01254,10047895,49,3418,47,3101,0.837118816,0.945844531,0.61885946,1.447102491,0.916017987,DB0125410047895_,0.087719278,-0.055677067,NA,10047895,Weight decreased,10022891,Investigations,Inv,dasatinib,DB01254
,16650,DB00285,10061428,159,10792,58,3660,0.637413884,0.929709718,0.682470987,1.281629389,0.774717312,DB0028510061428_,0.255257075,-0.072882873,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,venlafaxine,DB00285
,16651,DB00787,10061428,256,16744,268,16980,0.724891471,0.968681273,0.81186381,1.155594527,0.838634345,DB0078710061428_,0.17598049,-0.031819645,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,acyclovir,DB00787
,16652,DB00924,10061428,133,10029,52,4199,0.745594067,1.070863723,0.769944867,1.508618458,0.85479359,DB0092410061428_,0.156895254,0.068465541,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,cyclobenzaprine,DB00924
,16653,DB01015,10061428,131,9756,137,9244,0.424562799,0.906027281,0.706312137,1.161836071,0.593359431,DB0101510061428_,0.521954941,-0.098685861,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,sulfamethoxazole,DB01015
,16654,DB01254,10061428,61,3406,66,3082,0.325158317,0.836347086,0.578540167,1.207385256,0.493563155,DB0125410061428_,0.706104455,-0.178711577,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,dasatinib,DB01254
,16657,DB00060,10005750,43,9465,13,2452,0.61980955,0.856874134,0.45140754,1.739790638,0.760441282,DB0006010005750_,0.273856379,-0.15446424,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,interferon beta-1a,DB00060
,16659,DB00060,10028245,434,9074,131,2334,0.122141283,0.852147477,0.695472966,1.049735876,0.244499498,DB0006010028245_,1.408542023,-0.159995673,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,16660,DB00060,10037660,211,9297,70,2395,0.073196403,0.776527876,0.587550481,1.036678234,0.166851744,DB0006010037660_,1.790649621,-0.252922737,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,16661,DB00060,10046571,242,9266,58,2407,0.613531708,1.083841613,0.807676809,1.474840872,0.755259615,DB0006010046571_,0.280693728,0.080511779,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,interferon beta-1a,DB00060
,16663,DB00112,10003445,79,5854,33,4058,0.01535095,1.659399213,1.089959344,2.577732717,0.050214639,DB0011210003445_,2.991448686,0.506455617,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,16664,DB00441,10003445,54,2220,25,1869,0.016078984,1.818232935,1.107144907,3.061653709,0.05201995,DB0044110003445_,2.95612798,0.597865115,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,gemcitabine,DB00441
,16666,DB01248,10011906,256,2444,203,1171,7.64839033353688e-07,0.604287599,0.493995768,0.73988357,1.13070349334464e-05,DB0124810011906_,11.39008547,-0.503705036,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,16670,DB00112,10019211,214,5719,127,3964,0.178804781,1.167906132,0.929679003,1.472037452,0.322395641,DB0011210019211_,1.131975789,0.155212515,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,bevacizumab,DB00112
,16683,DB00073,10002034,124,7282,180,6227,6.82506470271827e-06,0.5891142,0.46361461,0.746607242,7.77451032333476e-05,DB0007310002034_,9.46207499,-0.529135226,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,rituximab,DB00073
,16684,DB00524,10002034,78,1499,56,1288,0.330138149,1.196723867,0.830918759,1.7329003,0.498774644,DB0052410002034_,0.695600901,0.179587712,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,metolazone,DB00524
,16687,DB00524,10003549,99,1478,64,1280,0.075894321,1.339512917,0.959225066,1.881428107,0.171315405,DB0052410003549_,1.764248948,0.292306053,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,16690,DB00927,10003549,244,7253,147,4869,0.319504648,1.114299373,0.901318091,1.381405418,0.487727492,DB0092710003549_,0.717998448,0.108225842,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,16697,DB00695,10010968,42,28007,8,20520,0.000136303,3.84641433,1.783478113,9.485886234,0.001038774,DB0069510010968_,6.869714184,1.347141371,female,10010968,Cor pulmonale,10007541,Cardiac disorders,Card,furosemide,DB00695
,16703,DB00524,10011906,139,1438,129,1215,0.479722228,0.910451358,0.702395881,1.180767313,0.64460146,DB0052410011906_,0.439123044,-0.093814805,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,16706,DB00927,10011906,362,7135,321,4695,0.000184475,0.742102219,0.633847402,0.869116638,0.001347489,DB0092710011906_,6.609512707,-0.298268284,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,16707,DB01073,10011906,28,1037,51,1599,0.559086733,0.846633218,0.510477718,1.378339335,0.711840552,DB0107310011906_,0.339901337,-0.166487715,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,fludarabine,DB01073
,16721,DB00927,10013968,466,7031,234,4782,0.000218898,1.354415571,1.149967,1.598533945,0.001554851,DB0092710013968_,6.466375778,0.303370049,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,16722,DB01073,10013968,30,1035,43,1607,0.808168556,1.083215938,0.651596067,1.779990391,0.896477889,DB0107310013968_,0.10928165,0.079934337,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fludarabine,DB01073
,16725,DB00381,10013971,259,29101,116,22771,3.52985685172438e-07,1.747063987,1.397175385,2.195526336,5.65400897913317e-06,DB0038110013971_,12.08314571,0.557936658,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,16726,DB00524,10013971,60,1517,26,1318,0.00290692,2.004511637,1.237359424,3.329721567,0.01316705,DB0052410013971_,4.330037804,0.695400459,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metolazone,DB00524
,16727,DB00635,10013971,203,32850,91,23703,0.000140473,1.609600697,1.250173511,2.085622855,0.001066107,DB0063510013971_,6.843741369,0.475986134,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,16728,DB00695,10013971,408,27641,193,20335,2.97811927554851e-07,1.555209412,1.305959851,1.857245152,4.85908536050854e-06,DB0069510013971_,12.23466034,0.441610207,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,16731,DB00927,10013971,66,7431,28,4988,0.044524517,1.582156768,1.000996312,2.561235797,0.114625557,DB0092710013971_,2.166084487,0.458788959,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,16733,DB01137,10013971,36,7736,25,5568,1,1.036443757,0.604424155,1.803375094,1,DB0113710013971_,0,0.035795389,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,16738,DB00635,10014080,33,33020,29,23765,0.44209881,0.818994215,0.48197729,1.398615413,0.610202658,DB0063510014080_,0.49396415,-0.199678259,NA,10014080,Ecchymosis,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,16744,DB00073,10016173,76,7330,47,6360,0.069820935,1.402999201,0.96099792,2.066956722,0.160981709,DB0007310016173_,1.826464529,0.338612232,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,rituximab,DB00073
,16747,DB00927,10016173,199,7298,119,4897,0.353810964,1.122122715,0.886915124,1.424563112,0.523667247,DB0092710016173_,0.646898822,0.115222173,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,famotidine,DB00927
,16749,DB01137,10016173,150,7622,94,5499,0.295501529,1.151232595,0.881556581,1.509796465,0.461373315,DB0113710016173_,0.773547769,0.14083319,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,levofloxacin,DB01137
,16750,DB00073,10017955,31,7375,39,6368,0.119964904,0.686363087,0.413536876,1.130304672,0.241343805,DB0007310017955_,1.421532784,-0.376348509,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,rituximab,DB00073
,16751,DB00524,10017955,61,1516,49,1295,0.770791403,1.063415831,0.712517043,1.594059673,0.874483718,DB0052410017955_,0.134121604,0.061486209,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,metolazone,DB00524
,16752,DB00635,10017955,187,32866,197,23597,0.000219845,0.68154802,0.554521955,0.837412059,0.001560314,DB0063510017955_,6.462868339,-0.383388568,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,16755,DB00927,10017955,65,7432,62,4954,0.045538063,0.698866937,0.484847962,1.008119755,0.116601042,DB0092710017955_,2.148997067,-0.358294917,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,16757,DB01137,10017955,41,7731,43,5550,0.095643746,0.684531296,0.434528267,1.076887344,0.20424876,DB0113710017955_,1.588416618,-0.379020914,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,16758,DB00073,10021143,41,7365,53,6354,0.061276726,0.667420402,0.432213542,1.024081924,0.145780762,DB0007310021143_,1.925651413,-0.404335144,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rituximab,DB00073
,16760,DB00381,10021143,163,29197,156,22731,0.070060417,0.813480533,0.648641179,1.020502219,0.161354425,DB0038110021143_,1.824151936,-0.206433282,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,16761,DB00524,10021143,49,1528,36,1308,0.509648314,1.165078473,0.737251466,1.856678688,0.670207421,DB0052410021143_,0.400168032,0.152788444,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metolazone,DB00524
,16762,DB00635,10021143,227,32826,181,23613,0.3139589,0.902156346,0.738261041,1.103717189,0.481498902,DB0063510021143_,0.730851329,-0.102967441,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,16763,DB00695,10021143,371,27678,248,20280,0.269252103,1.096136523,0.9298235,1.293906204,0.431779119,DB0069510021143_,0.83984112,0.091791746,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,16766,DB00927,10021143,77,7420,67,4949,0.123628287,0.766557891,0.544140807,1.082193153,0.246562429,DB0092710021143_,1.400140057,-0.265845057,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,16767,DB01073,10021143,52,1013,59,1591,0.111847758,1.384039901,0.926465624,2.062506008,0.228858659,DB0107310021143_,1.474650676,0.325006687,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fludarabine,DB01073
,16768,DB01137,10021143,65,7707,69,5524,0.027457535,0.675233614,0.472778795,0.963381859,0.079014812,DB0113710021143_,2.538119948,-0.392696553,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,16769,DB00073,10024384,73,7333,41,6366,0.029684596,1.545643475,1.038617752,2.328231106,0.084011803,DB0007310024384_,2.476797983,0.435440312,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,rituximab,DB00073
,16771,DB00381,10024384,44,29316,32,22855,0.817553153,1.071977481,0.664316334,1.747151247,0.902479843,DB0038110024384_,0.102608924,0.069505056,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,amlodipine,DB00381
,16773,DB00635,10024384,157,32896,148,23646,0.019818965,0.762534422,0.604888644,0.961672914,0.061334815,DB0063510024384_,2.791407653,-0.271107628,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,16774,DB00695,10024384,42,28007,38,20490,0.365697952,0.808622423,0.508678357,1.289185189,0.535299364,DB0069510024384_,0.62492913,-0.212423191,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,furosemide,DB00695
,16780,DB00073,10028533,35,7371,74,6333,6.93220831625676e-06,0.406392058,0.26339142,0.61638421,7.88118925574433e-05,DB0007310028533_,9.448446652,-0.900436926,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,rituximab,DB00073
,16784,DB00635,10028533,51,33002,64,23730,0.003224942,0.57300992,0.388520414,0.841263258,0.01434915,DB0063510028533_,4.244064593,-0.55685225,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,16785,DB00695,10028533,35,28014,39,20489,0.077201487,0.656388912,0.403563835,1.063871183,0.173572928,DB0069510028533_,1.751157435,-0.421001811,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,furosemide,DB00695
,16802,DB00381,10043554,128,29232,146,22741,0.0018031,0.682051855,0.533329035,0.871271698,0.008933084,DB0038110043554_,4.717993584,-0.382649591,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,amlodipine,DB00381
,16806,DB00927,10043554,73,7424,60,4956,0.247938898,0.812224329,0.568128798,1.164968715,0.407291666,DB0092710043554_,0.898225727,-0.207978709,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,famotidine,DB00927
,16807,DB00222,10046571,83,3123,40,3088,0.000168054,2.0515101,1.385596523,3.081895901,0.00124431,DB0022210046571_,6.689173874,0.718576156,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,glimepiride,DB00222
,16808,DB00381,10046571,669,28691,200,22687,8.09560074203111e-38,2.644899272,2.252952708,3.116077149,2.89514102726922e-35,DB0038110046571_,79.52744443,0.972632982,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,16809,DB00524,10046571,46,1531,27,1317,0.123433936,1.465372239,0.886332886,2.466269565,0.24628694,DB0052410046571_,1.401258002,0.382109298,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,metolazone,DB00524
,16812,DB00927,10046571,218,7279,60,4956,4.76047306518705e-11,2.473622536,1.846444794,3.357333821,1.63781458793772e-09,DB0092710046571_,20.22990305,0.90568369,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,famotidine,DB00927
,16814,DB01137,10046571,158,7614,73,5520,0.001516267,1.569082846,1.178945753,2.104828443,0.007761455,DB0113710046571_,4.858585435,0.450491274,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,levofloxacin,DB01137
,16818,DB00072,10012174,110,3613,15,320,0.134907527,0.649594117,0.371566816,1.214688402,0.26248524,DB0007210012174_,1.337560428,-0.431407546,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,trastuzumab,DB00072
,16819,DB00399,10012174,109,6883,80,4918,0.881880269,0.973516333,0.721047578,1.319090003,0.950593515,DB0039910012174_,0.050668736,-0.026840676,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,zoledronic acid,DB00399
,16820,DB00997,10012174,103,5228,51,3463,0.096793056,1.337734463,0.944563292,1.915266657,0.205966846,DB0099710012174_,1.580040065,0.290977484,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,doxorubicin,DB00997
,16821,DB01229,10012174,199,5542,81,2628,0.268659839,1.164968773,0.891395486,1.534230093,0.431079197,DB0122910012174_,0.841463455,0.152694282,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,paclitaxel,DB01229
,16824,DB00399,10027452,67,6925,18,4980,9.00853224932515e-05,2.67655219,1.56953603,4.793251439,0.000730155,DB0039910027452_,7.222253702,0.98452947,NA,10027452,Metastases to bone,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,zoledronic acid,DB00399
,16845,DB00072,10053762,177,3546,49,286,7.74535467511376e-11,0.291484,0.206132681,0.417978501,2.57541616237021e-09,DB0007210053762_,19.7772547,-1.232770162,male,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,trastuzumab,DB00072
,16846,DB00399,10053762,213,6779,120,4878,0.036903888,1.277219586,1.013194727,1.616113017,0.099392608,DB0039910053762_,2.308677533,0.244685517,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,zoledronic acid,DB00399
,16847,DB00997,10053762,323,5008,263,3251,0.008763615,0.797288954,0.671267108,0.947550582,0.032035548,DB0099710053762_,3.440909111,-0.226538114,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,doxorubicin,DB00997
,16849,DB00072,10061818,229,3494,30,305,0.047603669,0.66641297,0.444946231,1.028621224,0.120580364,DB0007210061818_,2.115438831,-0.405845726,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,trastuzumab,DB00072
,16850,DB00399,10061818,143,6849,63,4935,0.001017232,1.635450542,1.204829558,2.241472489,0.0055832,DB0039910061818_,5.187993221,0.491918327,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,16851,DB01229,10061818,311,5430,89,2620,1.05858602040485e-05,1.685960223,1.321426522,2.168835332,0.000114083,DB0122910061818_,9.078581075,0.522335267,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,16861,DB00112,10027457,74,5859,29,4062,0.008631031,1.768991567,1.134815825,2.825084908,0.031652132,DB0011210027457_,3.452949756,0.570409648,NA,10027457,Metastases to liver,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,bevacizumab,DB00112
,16866,DB00112,10033553,74,5859,16,4075,4.0246742051533e-06,3.216389808,1.852533436,5.927071578,4.88630768972076e-05,DB0011210033553_,9.92648852,1.168259553,female,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,bevacizumab,DB00112
,16868,DB01101,10033553,666,6923,233,3675,6.55325073871417e-08,1.51728206,1.297862065,1.778499779,1.23478276463872e-06,DB0110110033553_,13.6046155,0.416920616,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,capecitabine,DB01101
,16869,DB00112,10038695,39,5894,27,4064,1,0.995965874,0.593245708,1.694676968,1,DB0011210038695_,0,-0.004042285,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bevacizumab,DB00112
,16886,DB00073,10053762,711,6695,509,5898,0.000675794,1.230548867,1.090695267,1.389097015,0.003977439,DB0007310053762_,5.527117175,0.207460303,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,rituximab,DB00073
,16887,DB00860,10053762,125,1758,98,1398,0.944465561,1.014310316,0.764857645,1.348130837,0.983140361,DB0086010053762_,0.01700338,0.01420889,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisolone,DB00860
,16889,DB00762,10061818,108,1055,129,1240,0.945453934,0.984023211,0.744778542,1.298288581,0.984032812,DB0076210061818_,0.016096037,-0.016105794,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,irinotecan,DB00762
,16891,DB00333,10046571,34,3037,29,3123,0.527025123,1.205575331,0.710901231,2.056784175,0.684700245,DB0033310046571_,0.378774135,0.186956907,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,methadone,DB00333
,16900,DB00331,10003445,31,24915,39,20713,0.092666921,0.66082762,0.398506802,1.087259811,0.199488127,DB0033110003445_,1.61200056,-0.41426226,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,16901,DB00531,10003445,30,7222,32,6484,0.52559932,0.841711132,0.493480726,1.432087458,0.683571429,DB0053110003445_,0.380424124,-0.172318398,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,16902,DB00541,10003445,27,3107,48,4249,0.292464634,0.769277922,0.460429122,1.261079569,0.45806244,DB0054110003445_,0.780749772,-0.262302968,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,vincristine,DB00541
,16903,DB00635,10003445,57,32996,55,23739,0.125557618,0.745626032,0.505458954,1.100681764,0.249426141,DB0063510003445_,1.388592437,-0.293531103,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,16904,DB00997,10003445,58,5273,16,3498,0.001168976,2.404528118,1.361028664,4.488914744,0.006268551,DB0099710003445_,5.072210035,0.877353676,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,doxorubicin,DB00997
,16907,DB01073,10016256,40,1025,55,1595,0.593227836,1.131651893,0.727870314,1.746141769,0.739306845,DB0107310016256_,0.302042227,0.123678417,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fludarabine,DB01073
,16909,DB00331,10025197,41,24905,52,20700,0.047339465,0.655350268,0.424125792,1.006610657,0.120084717,DB0033110025197_,2.11955781,-0.422585426,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,metformin,DB00331
,16910,DB00722,10025197,47,25356,33,25999,0.11665969,1.460340996,0.915704088,2.353574579,0.236101373,DB0072210025197_,1.443494021,0.378669968,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,lisinopril,DB00722
,16912,DB00073,10030124,53,7353,66,6341,0.052278593,0.692533188,0.472367433,1.011113283,0.129300664,DB0007310030124_,2.045614858,-0.367399117,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,16914,DB00531,10030124,54,7198,60,6456,0.259911512,0.807239295,0.547466958,1.187781382,0.421168492,DB0053110030124_,0.864722307,-0.214135131,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,16915,DB00541,10030124,22,3112,34,4263,0.686281346,0.886422864,0.492831078,1.563584517,0.810755531,DB0054110030124_,0.209788712,-0.120561169,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,vincristine,DB00541
,16916,DB00635,10030124,393,32660,269,23525,0.526421154,1.052341302,0.898022915,1.234658247,0.684278119,DB0063510030124_,0.379390838,0.051017494,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,16917,DB00997,10030124,54,5277,32,3482,0.659468255,1.113498782,0.704498355,1.785911717,0.792018783,DB0099710030124_,0.233170172,0.107507114,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,16919,DB00073,10037660,286,7120,367,6040,3.05776871636902e-07,0.661112236,0.562248752,0.776777194,4.97206623629815e-06,DB0007310037660_,12.21167506,-0.413831657,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,16921,DB00331,10037660,333,24613,312,20440,0.130323914,0.886354827,0.756345627,1.038873006,0.256193559,DB0033110037660_,1.361822029,-0.120637926,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,16932,DB00531,10061428,101,7151,114,6402,0.098498602,0.793184735,0.599393144,1.04836169,0.208638155,DB0053110061428_,1.567153842,-0.231699128,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,cyclophosphamide,DB00531
,16933,DB00541,10061428,38,3096,85,4212,0.012617351,0.608248443,0.402396561,0.904490315,0.042856764,DB0054110061428_,3.149891791,-0.497171856,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,vincristine,DB00541
,16934,DB00997,10061428,96,5235,75,3439,0.270055899,0.840885223,0.613156794,1.156774583,0.432700302,DB0099710061428_,0.837709935,-0.173300106,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,doxorubicin,DB00997
,16938,DB00112,10061309,42,5891,37,4054,0.301356479,0.781192219,0.489135702,1.25222221,0.46764856,DB0011210061309_,0.760038205,-0.24693404,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,bevacizumab,DB00112
,16939,DB00958,10061309,60,4534,33,2552,1,1.023376455,0.656436033,1.620606893,1,DB0095810061309_,0,0.02310741,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,carboplatin,DB00958
,16944,DB00112,10008190,74,5859,54,4037,0.786192579,0.944236664,0.654304915,1.370223101,0.88396087,DB0011210008190_,0.123342482,-0.057378441,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,bevacizumab,DB00112
,16947,DB00073,10016288,166,7240,338,6069,2.03108339674887e-21,0.411713767,0.338763697,0.49885861,2.44894619649285e-19,DB0007310016288_,42.85345896,-0.88742691,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,rituximab,DB00073
,16952,DB00016,10061818,66,2696,47,2243,0.445527639,1.168266702,0.787974468,1.743899538,0.613446516,DB0001610061818_,0.488662198,0.155521199,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,16955,DB00073,10007882,50,7356,37,6370,0.518165427,1.170202042,0.748741586,1.843806787,0.677510079,DB0007310007882_,0.389330849,0.15717642,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,rituximab,DB00073
,16956,DB01060,10007882,68,8519,48,5033,0.385246331,0.836981093,0.568961585,1.239695376,0.555377602,DB0106010007882_,0.588107033,-0.177953797,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,16957,DB00073,10010305,36,7370,58,6349,0.003463348,0.534732856,0.342172795,0.825595291,0.015195143,DB0007310010305_,4.18677945,-0.625987991,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,rituximab,DB00073
,16958,DB01060,10010305,56,8531,55,5026,0.007684192,0.599907965,0.405322861,0.888195261,0.02884796,DB0106010010305_,3.545715991,-0.510979027,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,amoxicillin,DB01060
,16959,DB00073,10040047,130,7276,209,6198,1.46566420850313e-08,0.52988456,0.421217973,0.664536859,3.17078055312796e-07,DB0007310040047_,14.96411786,-0.635096108,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,rituximab,DB00073
,16960,DB00186,10003553,81,16820,6,10002,8.77784435762032e-11,8.028018382,3.530106457,22.52332166,2.8802094455342e-09,DB0018610003553_,19.66540282,2.082937721,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,16961,DB00203,10003553,69,13809,21,8917,0.001649081,2.121641352,1.284837149,3.643971888,0.008302261,DB0020310003553_,4.791227354,0.752190012,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,16962,DB00338,10003553,237,33437,65,22207,1.57208087277412e-11,2.421524987,1.832270115,3.239202415,5.80367215461627e-10,DB0033810003553_,21.26736008,0.884397502,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,16965,DB00682,10003553,95,19364,26,16338,3.86982322275175e-08,3.082645488,1.979094634,4.960395742,7.63937689898833e-07,DB0068210003553_,14.08477961,1.125788153,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,16966,DB00820,10003553,60,11855,10,5806,0.000766951,2.938363108,1.4909779,6.442676399,0.004416441,DB0082010003553_,5.422421176,1.07785266,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,16972,DB00186,10006451,166,16735,48,9960,4.62776208940348e-06,2.058208046,1.483025215,2.903342982,5.53163831377765e-05,DB0018610006451_,9.802441434,0.721835724,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,lorazepam,DB00186
,16973,DB00203,10006451,233,13645,54,8884,1.1666126018907e-13,2.809155446,2.078830447,3.855471349,5.90836459358326e-12,DB0020310006451_,25.85465204,1.032883885,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,sildenafil,DB00203
,16974,DB00374,10006451,229,17487,25,5699,4.08863393651616e-09,2.985263511,1.968781434,4.715216145,1.00111544500538e-07,DB0037410006451_,16.11698083,1.093688021,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,treprostinil,DB00374
,16975,DB00390,10006451,56,4089,17,3284,0.000211588,2.64522863,1.511270666,4.866093269,0.001510357,DB0039010006451_,6.495409073,0.9727575,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,digoxin,DB00390
,16976,DB00471,10006451,337,13852,55,5410,8.02662551632256e-11,2.392965408,1.791664393,3.248932197,2.65885131312588e-09,DB0047110006451_,19.74537164,0.872533353,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,montelukast,DB00471
,16977,DB00682,10006451,276,19183,81,16283,1.70660420667052e-19,2.89205933,2.247883261,3.756070416,1.68639442001258e-17,DB0068210006451_,38.62135381,1.061968819,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,warfarin,DB00682
,16979,DB01062,10006451,50,4436,11,1734,0.086427027,1.776659685,0.910266202,3.794131713,0.18907579,DB0106210006451_,1.665607337,0.57473502,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,oxybutynin,DB01062
,16980,DB01240,10006451,109,5642,14,1562,0.005322751,2.155230216,1.226676172,4.084142654,0.021501233,DB0124010006451_,3.839645003,0.767897547,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,16981,DB06403,10006451,223,21248,21,6640,1.27433386884768e-09,3.318449938,2.116229181,5.472220992,3.47107417022397e-08,DB0640310006451_,17.17621664,1.199497788,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,16983,DB00186,10013573,568,16333,231,9777,6.0884332405681e-07,1.471871561,1.258258592,1.726233303,9.22123121453947e-06,DB0018610013573_,11.59400199,0.386534761,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,16984,DB00338,10013573,1123,32551,667,21605,0.025542022,1.117517115,1.012875647,1.233617337,0.074708646,DB0033810013573_,2.594159456,0.111109363,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,16985,DB00471,10013573,442,13747,139,5326,0.034404827,1.231943355,1.013106762,1.505647943,0.094220763,DB0047110013573_,2.362114708,0.208592886,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,16986,DB00682,10013573,1048,18411,617,15747,3.54640123642435e-13,1.452749779,1.310925753,1.610981019,1.68871660325026e-11,DB0068210013573_,24.80446719,0.37345816,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,16987,DB00820,10013573,979,10936,298,5518,1.74724871961025e-14,1.657593247,1.448465997,1.90109644,9.93003947999039e-13,DB0082010013573_,27.63804176,0.505366699,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,16988,DB00879,10013573,24,1753,70,3642,0.181819747,0.71235163,0.426844704,1.151584635,0.326216037,DB0087910013573_,1.120195426,-0.339183627,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,emtricitabine,DB00879
,16989,DB01240,10013573,521,5230,105,1471,0.002255106,1.395501372,1.119994394,1.751860478,0.01072859,DB0124010013573_,4.534843121,0.333253757,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,epoprostenol,DB01240
,16990,DB09020,10013573,72,1882,37,1567,0.018807637,1.620026328,1.068540098,2.492526229,0.058869753,DB0902010013573_,2.832427852,0.482442401,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,bisacodyl,DB09020
,16991,DB00203,10013968,2977,10901,1114,7824,2.46318598962437e-69,1.917972312,1.779040628,2.068770643,2.75509973350114e-66,DB0020310013968_,150.9571625,0.651268541,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,16992,DB00390,10013968,497,3648,258,3043,2.40133088521801e-09,1.606774568,1.368833309,1.889350324,6.17602566711891e-08,DB0039010013968_,16.60000578,0.474228796,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,16993,DB00471,10013968,891,13298,320,5145,0.274754377,1.077270383,0.943083916,1.232908735,0.437970757,DB0047110013968_,0.825603136,0.074430418,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,16994,DB00879,10013968,31,1746,31,3681,0.003928004,2.107982339,1.234907995,3.598270148,0.016825161,DB0087910013968_,4.084879862,0.745731253,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,emtricitabine,DB00879
,16995,DB09020,10013968,98,1856,79,1525,0.93831094,1.019270194,0.744001512,1.399997983,0.978108824,DB0902010013968_,0.022134343,0.019086875,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bisacodyl,DB09020
,16996,DB00186,10017577,209,16692,84,9924,0.002330486,1.479242117,1.141549555,1.931405073,0.011019936,DB0018610017577_,4.508049269,0.391529874,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,16997,DB00203,10017577,177,13701,110,8828,0.807789311,1.036790948,0.811327131,1.329677065,0.896255547,DB0020310017577_,0.109529698,0.036130316,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,16998,DB00338,10017577,505,33169,203,22069,5.46326539601422e-10,1.655164588,1.402307355,1.959513334,1.59469107089654e-08,DB0033810017577_,17.95400071,0.503900453,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,16999,DB00374,10017577,173,17543,41,5683,0.078411443,1.366861638,0.966243335,1.973966778,0.175729614,DB0037410017577_,1.738808747,0.312517337,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,17000,DB00390,10017577,55,4090,40,3261,0.679066262,1.096320598,0.714334035,1.695583958,0.805744575,DB0039010017577_,0.215988491,0.091959663,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,17001,DB00471,10017577,168,14021,49,5416,0.093467584,1.3243336,0.956566494,1.862836005,0.200858067,DB0047110017577_,1.605156755,0.28090939,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,17002,DB00682,10017577,204,19255,128,16236,0.009223667,1.343852067,1.070981832,1.69135246,0.033370845,DB0068210017577_,3.400072663,0.295540167,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,17003,DB00820,10017577,151,11764,65,5751,0.422908,1.135653897,0.842160117,1.545953112,0.591819045,DB0082010017577_,0.524554358,0.127208606,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,17005,DB01062,10017577,135,4351,27,1718,0.000964999,1.974075279,1.292875557,3.117275999,0.0053507,DB0106210017577_,5.230527797,0.680100075,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,17006,DB01240,10017577,59,5692,19,1557,0.579021713,0.849417967,0.497472796,1.513551422,0.727772694,DB0124010017577_,0.317766513,-0.163203909,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,17007,DB06403,10017577,165,21306,42,6619,0.285885566,1.220451297,0.864105436,1.758085929,0.450550236,DB0640310017577_,0.797285696,0.199220706,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,17010,DB00338,10028035,58,33616,27,22245,0.149335293,1.421503068,0.885556179,2.335469922,0.283045729,DB0033810028035_,1.262146807,0.35171481,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,17021,DB00186,10047899,274,16627,102,9906,4.16398801955578e-05,1.600395969,1.26863519,2.032019824,0.000377676,DB0018610047899_,7.881474601,0.470251079,NA,10047899,Weight increased,10022891,Investigations,Inv,lorazepam,DB00186
,17022,DB00203,10047899,437,13441,176,8762,4.50802906238437e-08,1.618568794,1.352746674,1.943313404,8.78706295178147e-07,DB0020310047899_,13.94481513,0.481542298,NA,10047899,Weight increased,10022891,Investigations,Inv,sildenafil,DB00203
,17023,DB00338,10047899,605,33069,251,22021,1.31644416460925e-10,1.605068327,1.381733483,1.868870471,4.20701943668743e-09,DB0033810047899_,19.28651141,0.473166327,NA,10047899,Weight increased,10022891,Investigations,Inv,omeprazole,DB00338
,17024,DB00374,10047899,421,17295,135,5589,0.960200815,1.007771687,0.826205305,1.235571074,0.997781317,DB0037410047899_,0.002221148,0.007741643,NA,10047899,Weight increased,10022891,Investigations,Inv,treprostinil,DB00374
,17025,DB00390,10047899,100,4045,43,3258,0.000469777,1.872942829,1.293448809,2.752532119,0.002931296,DB0039010047899_,5.832310756,0.627510899,NA,10047899,Weight increased,10022891,Investigations,Inv,digoxin,DB00390
,17026,DB00471,10047899,236,13953,47,5418,1.2370094690756e-05,1.949723343,1.418106906,2.731165525,0.000130739,DB0047110047899_,8.942307447,0.667687487,NA,10047899,Weight increased,10022891,Investigations,Inv,montelukast,DB00471
,17027,DB00820,10047899,322,11593,112,5704,0.001565732,1.414534425,1.134606341,1.774168432,0.007961941,DB0082010047899_,4.833082527,0.346800448,NA,10047899,Weight increased,10022891,Investigations,Inv,tadalafil,DB00820
,17028,DB00879,10047899,24,1753,44,3668,0.603587598,1.141278935,0.661519588,1.925382163,0.747252903,DB0087910047899_,0.291351593,0.132149507,NA,10047899,Weight increased,10022891,Investigations,Inv,emtricitabine,DB00879
,17029,DB01062,10047899,60,4426,15,1730,0.153773197,1.563436097,0.873906211,2.972918878,0.289176876,DB0106210047899_,1.240716751,0.446886025,NA,10047899,Weight increased,10022891,Investigations,Inv,oxybutynin,DB01062
,17030,DB06403,10047899,472,20999,165,6496,0.186819901,0.884911457,0.737924497,1.065423278,0.332502359,DB0640310047899_,1.101108323,-0.122267687,NA,10047899,Weight increased,10022891,Investigations,Inv,ambrisentan,DB06403
,17046,DB00203,10064685,81,13797,38,8900,0.110052992,1.374994093,0.923335045,2.080312793,0.226136874,DB0020310064685_,1.486614826,0.318449435,NA,10064685,Device occlusion,10077536,Product issues,Prod,sildenafil,DB00203
,17048,DB00374,10064685,87,17629,27,5697,0.91331753,1.041318011,0.668628984,1.670439484,0.961184788,DB0037410064685_,0.039588601,0.040487229,NA,10064685,Device occlusion,10077536,Product issues,Prod,treprostinil,DB00374
,17051,DB00682,10064685,77,19382,50,16314,0.180530251,1.296220613,0.895775597,1.890501121,0.324492414,DB0068210064685_,1.125493122,0.259452809,NA,10064685,Device occlusion,10077536,Product issues,Prod,warfarin,DB00682
,17052,DB00820,10064685,79,11836,23,5793,0.026391964,1.681071796,1.044093826,2.806534041,0.076632177,DB0082010064685_,2.568738228,0.519431564,NA,10064685,Device occlusion,10077536,Product issues,Prod,tadalafil,DB00820
,17055,DB01240,10064685,156,5595,69,1507,0.001234794,0.60900751,0.453100793,0.825531833,0.006548282,DB0124010064685_,5.028552568,-0.495924679,NA,10064685,Device occlusion,10077536,Product issues,Prod,epoprostenol,DB01240
,17056,DB06403,10064685,49,21422,15,6646,1,1.013458483,0.558529602,1.94712415,1,DB0640310064685_,0,0.013368722,NA,10064685,Device occlusion,10077536,Product issues,Prod,ambrisentan,DB06403
,17059,DB00203,10069841,78,13800,28,8910,0.006909146,1.798556228,1.15335788,2.880121835,0.026523575,DB0020310069841_,3.629721333,0.586984248,NA,10069841,Device alarm issue,10077536,Product issues,Prod,sildenafil,DB00203
,17063,DB00682,10069841,75,19384,31,16333,0.000595955,2.038476317,1.324081385,3.207500978,0.003576004,DB0068210069841_,5.633509379,0.712202625,NA,10069841,Device alarm issue,10077536,Product issues,Prod,warfarin,DB00682
,17064,DB00820,10069841,63,11852,17,5799,0.031023781,1.813176372,1.046795773,3.308583175,0.08697777,DB0082010069841_,2.44210271,0.595080209,NA,10069841,Device alarm issue,10077536,Product issues,Prod,tadalafil,DB00820
,17067,DB01240,10069841,189,5562,59,1517,0.387027033,0.873700691,0.645190843,1.19788582,0.557134947,DB0124010069841_,0.584947793,-0.135017421,NA,10069841,Device alarm issue,10077536,Product issues,Prod,epoprostenol,DB01240
,17068,DB06403,10069841,44,21427,18,6643,0.368618252,0.757857827,0.428683253,1.394559285,0.538285042,DB0640310069841_,0.619367041,-0.277259474,NA,10069841,Device alarm issue,10077536,Product issues,Prod,ambrisentan,DB06403
,17071,DB00121,10008479,66,4157,6,462,0.842428209,1.222422288,0.528620999,3.470263083,0.919801687,DB0012110008479_,0.08359719,0.200834373,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,17074,DB00121,10012378,90,4133,12,456,0.504636323,0.827522541,0.446825821,1.674042465,0.665564402,DB0012110012378_,0.407119874,-0.189318932,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,biotin,DB00121
,17075,DB00126,10012378,195,9976,70,5875,0.000311236,1.640496527,1.239800886,2.192010152,0.002080316,DB0012610012378_,6.175235476,0.494998956,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ascorbic acid,DB00126
,17076,DB00341,10012378,213,11192,58,5010,0.000681523,1.643878764,1.221882195,2.241835627,0.00400348,DB0034110012378_,5.520591175,0.497058549,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,cetirizine,DB00341
,17080,DB00126,10013946,98,10073,28,5917,0.000549957,2.055856644,1.337116213,3.254848117,0.003338097,DB0012610013946_,5.702354324,0.72069262,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,17081,DB00169,10013946,318,38373,95,18080,6.78043200625747e-05,1.577149859,1.249500776,2.006405565,0.000571321,DB0016910013946_,7.467558946,0.455619332,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,17082,DB00341,10013946,82,11323,19,5049,0.009085938,1.924372432,1.156064264,3.361465416,0.032975452,DB0034110013946_,3.411991879,0.654599905,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,17083,DB00588,10013946,111,16413,47,8421,0.311574547,1.211679035,0.853208778,1.744485855,0.479025691,DB0058810013946_,0.736001048,0.19200703,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,17084,DB00863,10013946,123,10550,54,5786,0.179989391,1.249239878,0.898515099,1.756721035,0.323839099,DB0086310013946_,1.127508495,0.222535269,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,17086,DB00035,10016256,40,630,30,512,0.804935552,1.083556052,0.647934807,1.829140946,0.894429549,DB0003510016256_,0.111569139,0.080248273,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,desmopressin,DB00035
,17087,DB00121,10016256,396,3827,58,410,0.039415828,0.731518468,0.542964647,0.999362204,0.104471619,DB0012110016256_,2.258839834,-0.312632812,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,17088,DB00863,10016256,776,9897,377,5463,0.051388388,1.136199504,0.998773858,1.29412064,0.127627324,DB0086310016256_,2.058640791,0.127688925,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,17092,DB00126,10017885,101,10070,20,5925,1.0154178766968e-06,2.971148667,1.823847741,5.075234171,1.45160817737144e-05,DB0012610017885_,11.14025344,1.088948635,female,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,17093,DB00169,10017885,333,38358,87,18088,3.07969405073698e-07,1.804909702,1.420434486,2.314081758,5.00462183144492e-06,DB0016910017885_,12.20514871,0.590510564,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,17094,DB00341,10017885,99,11306,22,5046,0.002081382,2.008329507,1.253843647,3.352890604,0.010052148,DB0034110017885_,4.599968937,0.697303286,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,17095,DB00863,10017885,146,10527,81,5759,0.944301198,0.986071331,0.745026847,1.312824662,0.982988732,DB0086310017885_,0.017157622,-0.014026583,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,17097,DB00035,10019211,65,605,35,507,0.045941897,1.555758132,0.997565563,2.460811761,0.117394911,DB0003510019211_,2.142211716,0.441962971,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,desmopressin,DB00035
,17098,DB00121,10019211,272,3951,20,448,0.069212082,1.541965793,0.966511393,2.591784214,0.159912063,DB0012110019211_,1.833131222,0.433058092,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,biotin,DB00121
,17099,DB00863,10019211,649,10024,179,5661,1.49949277819956e-18,2.047509664,1.72675355,2.437464037,1.36145656908378e-16,DB0086310019211_,36.53280635,0.716624257,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,17103,DB00126,10022052,44,10127,11,5934,0.01099759,2.343721917,1.189944137,5.036732601,0.038402078,DB0012610022052_,3.2596437,0.851740229,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,17104,DB00169,10022052,172,38519,29,18146,1.38138550325881e-08,2.794020989,1.876520747,4.298513549,3.00701597955759e-07,DB0016910022052_,15.01714743,1.027481773,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,17105,DB00341,10022052,53,11352,7,5061,0.000693102,3.375078863,1.527764706,8.806363623,0.004057049,DB0034110022052_,5.507299524,1.216418691,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,17106,DB00451,10022052,205,47066,31,15388,1.91844539208804e-05,2.161895772,1.476183415,3.266509405,0.000192545,DB0045110022052_,8.555182945,0.770985509,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,17107,DB00588,10022052,60,16464,10,8458,0.000327923,3.082248185,1.564478624,6.757052923,0.002171419,DB0058810022052_,6.132374194,1.125659261,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,17113,DB00169,10027951,52,38639,28,18147,0.55056054,0.872226676,0.540582553,1.434771448,0.704654224,DB0016910027951_,0.350048059,-0.136705939,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,17119,DB00121,10028372,53,4170,7,461,0.662262706,0.837067799,0.376260962,2.195353964,0.794068754,DB0012110028372_,0.230585229,-0.177850209,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,biotin,DB00121
,17120,DB00126,10028372,94,10077,56,5889,0.932322737,0.980949812,0.696093944,1.393436948,0.973140202,DB0012610028372_,0.027227114,-0.019233981,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,17121,DB00169,10028372,436,38255,193,17982,0.519040312,1.061886775,0.893485299,1.265828999,0.67828252,DB0016910028372_,0.388191382,0.060047302,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,17122,DB00341,10028372,82,11323,35,5033,0.920013968,1.041365015,0.691963614,1.596732353,0.964563326,DB0034110028372_,0.036079792,0.040532367,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,17123,DB00451,10028372,444,46827,137,15282,0.594653084,1.057639636,0.870580363,1.291640989,0.740481451,DB0045110028372_,0.300454695,0.056039667,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,17124,DB00588,10028372,139,16385,52,8416,0.054891518,1.372986942,0.990460756,1.92856814,0.134141274,DB0058810028372_,2.008861748,0.316988616,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,17125,DB00863,10028372,116,10557,53,5787,0.293703088,1.199718274,0.858223958,1.696166031,0.459461599,DB0086310028372_,0.777699911,0.182086758,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,17129,DB00126,10028411,128,10043,60,5885,0.171149308,1.250100848,0.911321653,1.731420212,0.312406914,DB0012610028411_,1.163448728,0.223224226,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,17130,DB00169,10028411,546,38145,172,18003,2.33179188808276e-06,1.498195776,1.258735282,1.79045823,3.02747096953596e-05,DB0016910028411_,10.40519786,0.404261568,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,17131,DB00588,10028411,203,16321,85,8383,0.117880536,1.226631693,0.946327257,1.601621215,0.238015815,DB0058810028411_,1.435418158,0.204271952,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,17132,DB00863,10028411,137,10536,49,5791,0.010714657,1.536709064,1.099480231,2.179006016,0.037611479,DB0086310028411_,3.280445975,0.429643158,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,17135,DB00121,10028813,302,3921,21,447,0.033647314,1.63930086,1.03949992,2.71627382,0.092687031,DB0012110028813_,2.378526719,0.494269846,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,biotin,DB00121
,17136,DB00341,10028813,778,10627,200,4868,1.09188357086557e-13,1.781868615,1.517631946,2.099720484,5.5512881354355e-12,DB0034110028813_,25.91699112,0.577662597,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,17137,DB00588,10028813,1027,15497,278,8190,1.65455692031392e-24,1.952319793,1.703599536,2.243202298,2.45014245918037e-22,DB0058810028813_,49.76072588,0.669018303,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,17138,DB00863,10028813,861,9812,288,5552,1.00134684533338e-14,1.691566962,1.47236954,1.94767822,5.90143538779999e-13,DB0086310028813_,28.1584106,0.525655296,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,17142,DB00126,10028836,59,10112,19,5926,0.024798027,1.819733981,1.068313373,3.235776129,0.073044898,DB0012610028836_,2.61668099,0.598690326,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,17143,DB00169,10028836,265,38426,60,18115,6.21342596703524e-08,2.082106008,1.567076213,2.805253626,1.17665635117811e-06,DB0016910028836_,13.65283374,0.733379885,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,17144,DB00341,10028836,91,11314,13,5055,1.62361859426967e-05,3.127245932,1.738348166,6.103109669,0.000165999,DB0034110028836_,8.703529774,1.140152723,female,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,17145,DB00588,10028836,109,16415,36,8432,0.021901693,1.555272715,1.057133492,2.336868065,0.06639594,DB0058810028836_,2.71211937,0.44165091,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,17148,DB00121,10047700,125,4098,8,460,0.141612849,1.753732975,0.855469368,4.178652291,0.272027897,DB0012110047700_,1.301850655,0.561746645,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,biotin,DB00121
,17149,DB00126,10047700,329,9842,116,5829,9.67821975840387e-07,1.679713563,1.351716063,2.099322233,1.39012025327675e-05,DB0012610047700_,11.18353521,0.518623281,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,17150,DB00169,10047700,1189,37502,317,17858,1.81480966121007e-21,1.786063452,1.574529672,2.030687687,2.19320790551296e-19,DB0016910047700_,42.9637515,0.580014009,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,17151,DB00341,10047700,384,11021,139,4929,0.038308291,1.235490142,1.011921195,1.515617583,0.102247505,DB0034110047700_,2.280358883,0.211467767,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,17152,DB00588,10047700,544,15980,153,8315,3.04147617558378e-12,1.850048346,1.540326441,2.232736896,1.26196055683062e-10,DB0058810047700_,22.79318442,0.615211772,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,17153,DB00863,10047700,486,10187,189,5651,3.82030613894575e-05,1.426410477,1.199388383,1.701943272,0.000350877,DB0086310047700_,7.955073617,0.355161132,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,17158,DB00169,10047924,148,38543,48,18127,0.025871788,1.450109722,1.040119464,2.053437736,0.075409654,DB0016910047924_,2.584819981,0.371639224,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,17159,DB00341,10047924,127,11278,33,5035,0.00444975,1.718084107,1.161712215,2.606373273,0.018607276,DB0034110047924_,3.984202576,0.541209779,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,17160,DB00451,10047924,189,47082,38,15381,0.005318382,1.624764335,1.141250985,2.368288115,0.02149019,DB0045110047924_,3.840158743,0.485362781,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,17161,DB00863,10047924,83,10590,24,5816,0.004401359,1.899240234,1.192092713,3.1324589,0.018452785,DB0086310047924_,3.992539998,0.641453929,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,17174,DB00126,10052904,65,10106,25,5920,0.079613886,1.523017789,0.945691104,2.524452197,0.177765119,DB0012610052904_,1.727292156,0.420693754,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,17175,DB00169,10052904,349,38342,85,18090,8.02799826444777e-09,1.937161252,1.523175513,2.487001533,1.84293392472498e-07,DB0016910052904_,15.50673682,0.661223629,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,17176,DB00341,10052904,73,11332,17,5051,0.015622626,1.913946804,1.116175145,3.465664515,0.050897463,DB0034110052904_,2.977942191,0.6491675,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,17177,DB00588,10052904,84,16440,25,8443,0.014843767,1.725542103,1.09186884,2.817805731,0.048902477,DB0058810052904_,3.017927234,0.545541263,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,17178,DB00863,10052904,69,10604,19,5821,0.006954419,1.993457448,1.184296136,3.512665536,0.026664459,DB0086310052904_,3.624423741,0.689870542,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,17180,DB08865,10028813,180,1031,100,871,0.001578833,1.520366233,1.163780179,1.994484938,0.008013058,DB0886510028813_,4.826682863,0.418951249,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,crizotinib,DB08865
,17182,DB08865,10030124,33,1178,28,943,0.896204611,0.943506135,0.54849279,1.633320194,0.956301489,DB0886510030124_,0.044682051,-0.058152412,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,crizotinib,DB08865
,17185,DB00007,10053762,114,1833,93,4359,7.89608226207996e-14,2.914499137,2.184209991,3.89710772,4.10580657287382e-12,DB0000710053762_,26.21861891,1.069697982,female,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,leuprolide,DB00007
,17203,DB00564,10033425,48,2556,17,1446,0.117375101,1.597177714,0.898119981,2.974110985,0.237250426,DB0056410033425_,1.438639047,0.468238143,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,carbamazepine,DB00564
,17204,DB00927,10033425,176,7321,72,4944,0.000304211,1.650710909,1.244793077,2.208171315,0.002040625,DB0092710033425_,6.194499153,0.501206049,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,famotidine,DB00927
,17205,DB00997,10033425,69,5262,13,3501,3.72333641496807e-06,3.530971546,1.931406527,6.973483255,4.56154265520558e-05,DB0099710033425_,9.995264597,1.261573059,female,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,doxorubicin,DB00997
,17206,DB01015,10033425,118,9769,67,9314,0.000649866,1.679112142,1.231990319,2.304495109,0.003850272,DB0101510033425_,5.559611583,0.518265167,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfamethoxazole,DB01015
,17209,DB00927,10033557,70,7427,16,5000,3.27521922645391e-05,2.945087837,1.690806066,5.439742004,0.000306531,DB0092710033557_,8.090192757,1.080138643,female,10033557,Palpitations,10007541,Cardiac disorders,Card,famotidine,DB00927
,17211,DB01015,10033557,44,9843,23,9358,0.019841025,1.818717394,1.07377638,3.15827936,0.06136628,DB0101510033557_,2.790894777,0.598131524,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,sulfamethoxazole,DB01015
,17213,DB01234,10033557,124,31501,38,32850,1.15372382234806e-12,3.403102735,2.347961613,5.033332142,5.15303834671519e-11,DB0123410033557_,23.68884951,1.224687585,female,10033557,Palpitations,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,17215,DB00564,10037087,37,2567,24,1439,0.592379646,0.864259424,0.50116894,1.516600995,0.738542854,DB0056410037087_,0.30307615,-0.145882296,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,carbamazepine,DB00564
,17216,DB00927,10037087,203,7294,72,4944,1.41815116384151e-06,1.910969249,1.449866005,2.542889901,1.95932212045067e-05,DB0092710037087_,10.84032691,0.647610573,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,famotidine,DB00927
,17217,DB00997,10037087,37,5294,16,3498,0.162233205,1.527909158,0.827754875,2.946662908,0.300385022,DB0099710037087_,1.202690219,0.423900237,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,doxorubicin,DB00997
,17218,DB01015,10037087,211,9676,137,9244,0.000516115,1.471348253,1.178688526,1.841570783,0.003168904,DB0101510037087_,5.754369429,0.386179159,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,17219,DB01229,10037087,71,5670,19,2690,0.030273888,1.772750947,1.053940366,3.122284977,0.085287409,DB0122910037087_,2.461728441,0.572532547,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,paclitaxel,DB01229
,17220,DB01234,10037087,530,31095,354,32534,5.39848215836404e-11,1.566438484,1.365411683,1.798779139,1.8392625214854e-09,DB0123410037087_,20.11390115,0.448804561,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,17228,DB00999,10022116,74,21356,16,12223,0.00016004,2.647020026,1.52646174,4.872069671,0.001192527,DB0099910022116_,6.731680542,0.973434489,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,17229,DB00999,10033425,609,20821,226,12013,9.61543267310921e-09,1.554723634,1.330127441,1.822370575,2.17225309679996e-07,DB0099910033425_,15.34233073,0.441297802,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,17235,DB00999,10048959,519,20911,210,12029,1.50296329641392e-05,1.421668647,1.206801022,1.679551879,0.000155288,DB0099910048959_,8.770225986,0.351831285,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,17238,DB00999,10049438,48,21382,13,12226,0.015838301,2.111178077,1.12531385,4.249322139,0.05144072,DB0099910049438_,2.967325204,0.747246122,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,17240,DB00999,10051055,142,21288,102,12137,0.08232351,0.793734734,0.610479807,1.035002277,0.182220923,DB0099910051055_,1.702535468,-0.231005961,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,hydrochlorothiazide,DB00999
,17241,DB00999,10061284,41,21389,10,12229,0.012776608,2.344089224,1.154190276,5.249823062,0.043280676,DB0099910061284_,3.140049024,0.851896936,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,17246,DB00441,10002034,150,2124,91,1803,0.013690904,1.399121975,1.062660398,1.850174255,0.045737186,DB0044110002034_,3.084843618,0.335844879,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,gemcitabine,DB00441
,17247,DB00537,10002034,104,7453,78,4220,0.073596638,0.754991525,0.556060291,1.028595905,0.167520421,DB0053710002034_,1.786650018,-0.281048755,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ciprofloxacin,DB00537
,17248,DB00788,10002034,107,9249,100,4961,9.29347516651337e-05,0.573926202,0.431890371,0.763275865,0.000749322,DB0078810002034_,7.196341667,-0.555254458,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,naproxen,DB00788
,17249,DB00956,10002034,64,5750,56,3411,0.03668627,0.67801699,0.464971055,0.991062359,0.098944681,DB0095610002034_,2.31319436,-0.388582933,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,hydrocodone,DB00956
,17250,DB00073,10002855,48,7358,36,6371,0.58354771,1.154467952,0.732827172,1.833389683,0.731539361,DB0007310002855_,0.312604251,0.14363959,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,rituximab,DB00073
,17251,DB00333,10002855,53,3018,46,3106,0.418918067,1.185735355,0.781005427,1.806067658,0.587972841,DB0033310002855_,0.53107452,0.170363135,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,methadone,DB00333
,17253,DB00537,10002855,140,7417,48,4250,0.002134801,1.671205429,1.19328379,2.375910103,0.01026681,DB0053710002855_,4.57883891,0.51354518,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ciprofloxacin,DB00537
,17254,DB00788,10002855,204,9152,58,5003,5.74261693282858e-06,1.922643256,1.426657752,2.625868122,6.67158833500107e-05,DB0078810002855_,9.615067502,0.653700935,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,naproxen,DB00788
,17255,DB00956,10002855,150,5664,55,3412,0.001631054,1.642829019,1.194807041,2.28723438,0.008224103,DB0095610002855_,4.80068605,0.496419767,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,hydrocodone,DB00956
,17257,DB00073,10011224,152,7254,149,6258,0.292927196,0.880075334,0.695603017,1.113622232,0.458500051,DB0007310011224_,0.779794877,-0.127747768,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rituximab,DB00073
,17259,DB00441,10011224,68,2206,33,1861,0.011092598,1.738118247,1.125044923,2.733211947,0.038656802,DB0044110011224_,3.253032536,0.552803061,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gemcitabine,DB00441
,17260,DB00537,10011224,121,7436,76,4222,0.501737593,0.903972971,0.671166531,1.223900986,0.663172134,DB0053710011224_,0.410720694,-0.100955818,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ciprofloxacin,DB00537
,17261,DB00788,10011224,172,9184,72,4989,0.067820006,1.297704986,0.977747205,1.73715474,0.157408289,DB0078810011224_,1.848912284,0.260597309,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,naproxen,DB00788
,17262,DB00956,10011224,95,5719,52,3415,0.667723487,1.090917365,0.767740722,1.565035087,0.798169392,DB0095610011224_,0.225434433,0.087018962,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrocodone,DB00956
,17264,DB00333,10011906,273,2798,300,2852,0.404912983,0.927596929,0.777837887,1.105747985,0.574636923,DB0033310011906_,0.554016876,-0.075157984,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,methadone,DB00333
,17265,DB00537,10011906,171,7386,192,4106,5.8829067458647e-11,0.495132965,0.39909072,0.613910378,1.99396781192848e-09,DB0053710011906_,20.03313931,-0.702928936,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,17266,DB00788,10011906,204,9152,215,4846,6.50505562186013e-12,0.502423105,0.411452423,0.613386106,2.57702165818528e-10,DB0078810011906_,22.07921659,-0.688312675,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,17267,DB00956,10011906,325,5489,293,3174,1.3888750701282e-07,0.641461243,0.542669018,0.758357822,2.44846285837155e-06,DB0095610011906_,12.92005014,-0.444006513,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,17268,DB09104,10011906,56,994,96,776,5.65123013145466e-06,0.455582044,0.317253659,0.649194239,6.57850239173099e-05,DB0910410011906_,9.629118346,-0.78617946,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,magnesium hydroxide,DB09104
,17269,DB00333,10013968,70,3001,62,3090,0.428681709,1.162486366,0.810843851,1.670000357,0.597212069,DB0033310013968_,0.515483005,0.150561131,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methadone,DB00333
,17270,DB00441,10013968,144,2130,94,1800,0.060591433,1.294494646,0.983443139,1.710359836,0.144510099,DB0044110013968_,1.934405882,0.258120385,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gemcitabine,DB00441
,17271,DB00537,10013968,232,7325,147,4151,0.302465742,0.894378391,0.721615663,1.111275315,0.468827608,DB0053710013968_,0.757520151,-0.111626338,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ciprofloxacin,DB00537
,17272,DB00788,10013968,259,9097,148,4913,0.598516512,0.945123547,0.766933463,1.168186882,0.743338051,DB0078810013968_,0.296604357,-0.056439622,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,naproxen,DB00788
,17273,DB00956,10013968,197,5617,113,3354,0.765478606,1.040988352,0.818424201,1.329188088,0.87062613,DB0095610013968_,0.138542637,0.0401706,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrocodone,DB00956
,17274,DB09104,10013968,61,989,27,845,0.005851127,1.929673927,1.195404393,3.188656571,0.023209367,DB0910410013968_,3.763199339,0.657351039,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium hydroxide,DB09104
,17275,DB00333,10016256,115,2956,94,3058,0.105413819,1.26556757,0.950556019,1.688436148,0.219226381,DB0033310016256_,1.51765038,0.235520693,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,methadone,DB00333
,17276,DB00441,10016256,254,2020,182,1712,0.104044253,1.182760895,0.96307807,1.454653039,0.217116814,DB0044110016256_,1.527319755,0.167851447,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,gemcitabine,DB00441
,17277,DB00537,10016256,395,7162,208,4090,0.36164967,1.084487088,0.910388209,1.294813261,0.531460778,DB0053710016256_,0.632125878,0.081107145,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,17278,DB00788,10016256,568,8788,275,4786,0.127325337,1.124870827,0.967975209,1.309491983,0.251897328,DB0078810016256_,1.378733702,0.117668208,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,17279,DB00956,10016256,360,5454,183,3284,0.074540876,1.184455849,0.983251615,1.43063472,0.169073386,DB0095610016256_,1.777422423,0.16928347,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,17280,DB09104,10016256,78,972,37,835,0.00363303,1.810433868,1.194844848,2.786178268,0.015789384,DB0910410016256_,4.148417438,0.593566523,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,magnesium hydroxide,DB09104
,17294,DB00073,10021015,37,7369,14,6393,0.007122622,2.292616949,1.209306299,4.59513223,0.027164555,DB0007310021015_,3.605842279,0.829693938,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,rituximab,DB00073
,17300,DB00073,10025310,24,7382,49,6358,0.000377948,0.421877229,0.247265872,0.701812345,0.00244749,DB0007310025310_,6.012692234,-0.863040934,NA,10025310,Lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,rituximab,DB00073
,17307,DB00333,10028813,148,2923,112,3040,0.013405033,1.3742447,1.061966658,1.7822774,0.04496284,DB0033310028813_,3.101918911,0.317904271,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,methadone,DB00333
,17308,DB00441,10028813,269,2005,144,1750,5.52675243047796e-06,1.630277353,1.31277258,2.030795216,6.45504055254891e-05,DB0044110028813_,9.648064158,0.488750155,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,gemcitabine,DB00441
,17309,DB00788,10028813,577,8779,206,4855,6.58651541445752e-08,1.548960035,1.31362704,1.832161251,1.2388304663257e-06,DB0078810028813_,13.6013428,0.437583761,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,17310,DB00956,10028813,382,5432,139,3328,1.26113142303068e-07,1.683637655,1.375997926,2.069451073,2.2458563315963e-06,DB0095610028813_,13.00642367,0.520956723,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,hydrocodone,DB00956
,17311,DB09104,10028813,73,977,38,834,0.018090485,1.639460344,1.080122785,2.522883359,0.057072158,DB0910410028813_,2.863438883,0.494367129,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,magnesium hydroxide,DB09104
,17312,DB00073,10029410,37,7369,42,6365,0.257974883,0.760945164,0.474974745,1.214534805,0.418882493,DB0007310029410_,0.870164844,-0.273193982,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,rituximab,DB00073
,17320,DB00441,10030124,64,2210,43,1851,0.28077351,1.246529412,0.829446627,1.889345965,0.444639819,DB0044110030124_,0.810490721,0.220363219,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,gemcitabine,DB00441
,17321,DB00537,10030124,54,7503,42,4256,0.135736806,0.729351513,0.477361547,1.120968771,0.263721684,DB0053710030124_,1.33286096,-0.315599478,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,17322,DB00956,10030124,48,5766,33,3434,0.564494697,0.866287518,0.543495937,1.396044352,0.71628014,DB0095610030124_,0.333683931,-0.143538418,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,17324,DB00073,10033371,229,7177,100,6307,3.14179977342497e-09,2.012301435,1.580084189,2.577789111,7.90260354492587e-08,DB0007310033371_,16.35348848,0.69927906,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,17325,DB00333,10033371,123,2948,82,3070,0.002190909,1.561953244,1.165943654,2.101482265,0.010480082,DB0033310033371_,4.558278802,0.445937117,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,methadone,DB00333
,17326,DB00441,10033371,124,2150,54,1840,2.97019117509661e-05,1.964893851,1.407113591,2.77472828,0.000281389,DB0044110033371_,8.175771262,0.675438224,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,gemcitabine,DB00441
,17327,DB00537,10033371,287,7270,136,4162,0.079851865,1.208060775,0.978066096,1.498059635,0.178160281,DB0053710033371_,1.72507168,0.189016409,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,17328,DB00788,10033371,507,8849,172,4889,2.4352533781519e-08,1.628513813,1.362141008,1.954424617,5.01454250252429e-07,DB0078810033371_,14.50575346,0.487667828,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,17329,DB00956,10033371,363,5451,144,3323,1.64554788023299e-05,1.536663986,1.257088334,1.886272592,0.000168104,DB0095610033371_,8.690926177,0.429613824,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,17330,DB09104,10033371,33,1017,21,851,0.405754154,1.314745649,0.732061421,2.410490351,0.575333672,DB0910410033371_,0.552805108,0.273643224,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,magnesium hydroxide,DB09104
,17337,DB00073,10047700,198,7208,154,6253,0.330032817,1.115340211,0.896429746,1.389816408,0.498658501,DB0007310047700_,0.695833785,0.109159481,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,rituximab,DB00073
,17338,DB00333,10047700,92,2979,87,3065,0.596035111,1.087966953,0.799005585,1.482406604,0.741464914,DB0033310047700_,0.299127437,0.084310774,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,methadone,DB00333
,17339,DB00441,10047700,185,2089,98,1796,0.000155076,1.622791473,1.25272664,2.11235045,0.001160476,DB0044110047700_,6.758925206,0.484147798,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,gemcitabine,DB00441
,17340,DB00788,10047700,280,9076,119,4942,0.025456692,1.281206358,1.027196112,1.605960159,0.074513269,DB0078810047700_,2.596778068,0.247802102,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,17341,DB00956,10047700,191,5623,77,3390,0.003137887,1.495396123,1.137752277,1.981584213,0.014031877,DB0095610047700_,4.266423645,0.402391137,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,hydrocodone,DB00956
,17342,DB09104,10047700,42,1008,30,842,0.54824289,1.169349373,0.707731418,1.953376625,0.702714408,DB0910410047700_,0.352804718,0.156447503,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,magnesium hydroxide,DB09104
,17346,DB00788,10055798,38,9318,18,5043,0.676889067,1.142533674,0.635501628,2.129158716,0.804024607,DB0078810055798_,0.218125404,0.133248318,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,naproxen,DB00788
,17360,DB00788,10060800,62,9294,15,5046,0.003783382,2.24400419,1.260007613,4.251958898,0.016309341,DB0078810060800_,4.116017266,0.808261855,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,naproxen,DB00788
,17363,DB00073,10066901,176,7230,59,6348,1.43184308488397e-11,2.618843574,1.935740659,3.586761789,5.319575333735e-10,DB0007310066901_,21.35445745,0.962732836,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,17367,DB00788,10066901,37,9319,20,5041,1,1.00075032,0.565257007,1.821782266,1,DB0078810066901_,0,0.000750039,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,17370,DB00073,10035528,100,7306,134,6273,0.000912044,0.640781162,0.488394995,0.838399578,0.005109354,DB0007310035528_,5.276682396,-0.445067281,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,rituximab,DB00073
,17371,DB00073,10008531,179,7227,276,6131,5.62872238727494e-10,0.55022684,0.45187234,0.668656713,1.6375314659604e-08,DB0007310008531_,17.92749084,-0.597424649,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,17372,DB00091,10008531,49,5461,24,2646,1,0.989239301,0.593902894,1.689572407,1,DB0009110008531_,0,-0.010819014,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,17373,DB00531,10008531,71,7181,108,6408,0.000501444,0.586669358,0.427709719,0.800418043,0.003098006,DB0053110008531_,5.776996673,-0.533293893,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,17374,DB00541,10008531,34,3100,68,4229,0.069952567,0.682131403,0.436905052,1.047262779,0.16121198,DB0054110008531_,1.825035135,-0.382532966,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,vincristine,DB00541
,17380,DB00531,10033645,20,7232,54,6462,1.03831974739321e-05,0.33096147,0.187433632,0.562694744,0.000112152,DB0053110033645_,9.095653802,-1.105753316,male,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,17381,DB00541,10033645,20,3114,70,4227,9.07498061553508e-05,0.387882767,0.222964996,0.646757451,0.000734635,DB0054110033645_,7.21613728,-0.947052132,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,vincristine,DB00541
,17386,DB00091,10061428,45,5465,22,2648,1,0.991101402,0.581419381,1.736863186,1,DB0009110061428_,0,-0.008938427,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,cyclosporine,DB00091
,17388,DB00335,10053762,239,8227,128,5337,0.092935588,1.211238613,0.970381848,1.517605857,0.199976417,DB0033510053762_,1.609555836,0.191643483,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,atenolol,DB00335
,17389,DB01270,10053762,96,1162,59,910,0.178899968,1.274111594,0.900570818,1.814928507,0.322534083,DB0127010053762_,1.131546464,0.242249147,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ranibizumab,DB01270
,17390,DB00588,10003988,390,16134,148,8320,0.001471437,1.358873661,1.119586564,1.656445325,0.007569063,DB0058810003988_,4.883686041,0.306656166,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,17392,DB01104,10003988,263,15200,88,7198,0.004676248,1.415265665,1.105761051,1.825935432,0.019378083,DB0110410003988_,3.943612613,0.347317263,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,17405,DB00575,10013709,272,4972,190,3639,0.663518968,1.047773267,0.86289455,1.274191715,0.795012926,DB0057510013709_,0.229396905,0.046667214,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,17411,DB00575,10017885,32,5212,22,3807,0.890590689,1.062447509,0.597372696,1.922454079,0.954671384,DB0057510017885_,0.046388098,0.060575217,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,clonidine,DB00575
,17413,DB01104,10017885,95,15368,35,7251,0.22177315,1.280611658,0.859854882,1.946892183,0.375732847,DB0110410017885_,0.978876901,0.247337821,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,17418,DB00575,10019211,225,5019,109,3720,0.00029366,1.529894494,1.206776821,1.949055153,0.001983414,DB0057510019211_,6.222935699,0.425198775,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,17419,DB00588,10020772,247,16277,87,8381,0.002024653,1.461816826,1.138731273,1.89132067,0.009822442,DB0058810020772_,4.6230855,0.379680064,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,fluticasone propionate,DB00588
,17421,DB01104,10020772,159,15304,71,7215,0.776373895,1.055768991,0.792066273,1.419118707,0.878078691,DB0110410020772_,0.130019064,0.054269403,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,sertraline,DB01104
,17439,DB00588,10029148,59,16465,28,8440,0.820726477,1.080121428,0.677299231,1.760738903,0.904519726,DB0058810029148_,0.100351166,0.077073468,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,fluticasone propionate,DB00588
,17441,DB01104,10029148,52,15411,22,7264,0.710147931,1.114094742,0.664289886,1.92782859,0.827129206,DB0110410029148_,0.189794361,0.108042184,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,sertraline,DB01104
,17443,DB00588,10031161,89,16435,24,8444,0.003775049,1.905228979,1.201533888,3.130432624,0.016278756,DB0058810031161_,4.117894322,0.6446022,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,17445,DB01104,10031161,61,15402,12,7274,0.003594964,2.400660965,1.278794604,4.901523569,0.015654245,DB0110410031161_,4.157013132,0.875744101,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,17446,DB00588,10033371,705,15819,200,8268,3.37836488564497e-15,1.842343821,1.568688662,2.171420921,2.12695379686654e-13,DB0058810033371_,29.1789154,0.611038577,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,17448,DB00575,10033425,113,5131,53,3776,0.006911176,1.568957986,1.1191834,2.223638669,0.026527491,DB0057510033425_,3.629573693,0.450411696,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,clonidine,DB00575
,17449,DB00588,10033425,393,16131,129,8339,5.44304423248817e-06,1.574882402,1.285262568,1.940143728,6.37000969060337e-05,DB0058810033425_,9.661324474,0.454180604,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,17450,DB01104,10033425,291,15172,92,7194,0.000601719,1.499773137,1.180333542,1.920584333,0.003606475,DB0110410033425_,5.625024461,0.405313855,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,17459,DB00575,10048959,123,5121,55,3774,0.00209852,1.648031075,1.186288164,2.314695687,0.010121955,DB0057510048959_,4.593048477,0.499581288,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,17460,DB00588,10048959,330,16194,147,8321,0.156949711,1.15348154,0.945115369,1.413281062,0.29339472,DB0058810048959_,1.22623641,0.142784795,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,17462,DB01104,10048959,235,15228,81,7205,0.015023286,1.372704393,1.060219827,1.792465269,0.049376668,DB0110410048959_,3.008277282,0.316782804,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,17478,DB01104,10058920,39,15424,22,7264,0.494459003,0.834895442,0.48250664,1.479519974,0.656954275,DB0110410058920_,0.42014086,-0.180448781,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,17480,DB00588,10060933,56,16468,24,8444,0.554284868,1.196390537,0.728895321,2.019946121,0.707835484,DB0058810060933_,0.34554358,0.179309138,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,17482,DB01104,10060933,49,15414,24,7262,0.900201289,0.961904765,0.578425496,1.640508909,0.956657329,DB0110410060933_,0.04431002,-0.03883983,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,17519,DB00073,10000087,38,7368,28,6379,0.538686004,1.174960516,0.701431784,1.990163167,0.69458005,DB0007310000087_,0.364447861,0.161234544,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,rituximab,DB00073
,17521,DB00073,10051792,244,7162,174,6233,0.052005613,1.220384639,0.997510745,1.495640482,0.128819363,DB0007310051792_,2.04934414,0.199166087,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,rituximab,DB00073
,17522,DB00207,10010305,58,9022,25,5430,0.173798869,1.396289273,0.858525832,2.33245762,0.315905074,DB0020710010305_,1.152313511,0.333818199,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,azithromycin,DB00207
,17523,DB00502,10010305,38,1356,54,1818,0.831158332,0.943467328,0.602295593,1.464974715,0.911697064,DB0050210010305_,0.09244751,-0.058193544,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,haloperidol,DB00502
,17524,DB00531,10010305,62,7190,90,6426,0.003247111,0.615716182,0.437380638,0.861985194,0.014427029,DB0053110010305_,4.238651785,-0.484969165,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,cyclophosphamide,DB00531
,17525,DB00541,10010305,22,3112,49,4248,0.069360029,0.612914432,0.35211333,1.035533892,0.160169414,DB0054110010305_,1.831523186,-0.489529942,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,vincristine,DB00541
,17526,DB00761,10010305,174,15133,115,8510,0.195455082,0.850868664,0.667408923,1.088102852,0.343624963,DB0076110010305_,1.06820444,-0.161497493,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,potassium chloride,DB00761
,17528,DB01075,10010305,170,19778,118,10979,0.064106504,0.799757455,0.627888823,1.021453198,0.150845707,DB0107510010305_,1.891497769,-0.223446778,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,17529,DB01136,10010305,124,9760,99,11016,0.010402001,1.413676965,1.075113603,1.862824878,0.036729794,DB0113610010305_,3.304167034,0.346194086,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,carvedilol,DB01136
,17530,DB01137,10010305,99,7673,62,5531,0.42186423,1.150976212,0.827916207,1.610820719,0.590908918,DB0113710010305_,0.526093389,0.140610463,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,levofloxacin,DB01137
,17531,DB00404,10011224,334,19558,103,9759,1.2668882130223e-05,1.61801896,1.291757808,2.040968118,0.000133601,DB0040410011224_,8.920649586,0.481202537,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,17533,DB00531,10011224,107,7145,109,6407,0.372174241,0.880266593,0.666302016,1.162712343,0.541837211,DB0053110011224_,0.612789672,-0.127530471,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclophosphamide,DB00531
,17534,DB00541,10011224,42,3092,99,4198,0.002518515,0.576035668,0.390382568,0.837113685,0.011728084,DB0054110011224_,4.44576894,-0.551585697,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vincristine,DB00541
,17535,DB00761,10011224,437,14870,167,8458,1.13817287048198e-05,1.488383156,1.239841658,1.793399636,0.00012149,DB0076110011224_,9.015679893,0.397690401,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,17536,DB00860,10011224,47,1836,55,1441,0.054107972,0.670787227,0.441685608,1.015129719,0.132689093,DB0086010011224_,2.019746533,-0.39930329,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisolone,DB00860
,17537,DB01075,10011224,471,19477,241,10856,0.303726794,1.089317605,0.928985552,1.27989182,0.470279145,DB0107510011224_,0.754428834,0.08555145,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,17539,DB00818,10013968,31,1389,33,1644,0.704903459,1.111813829,0.654869027,1.88320521,0.823063209,DB0081810013968_,0.194722278,0.105992762,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,propofol,DB00818
,17540,DB00860,10013968,77,1806,64,1432,0.79553579,0.953959813,0.670665529,1.360824925,0.889323278,DB0086010013968_,0.117294468,-0.047133733,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisolone,DB00860
,17541,DB01075,10013968,924,19024,477,10620,0.180054851,1.0813819,0.964662169,1.213354382,0.32389418,DB0107510013968_,1.127338421,0.078239761,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,17542,DB00207,10018964,54,9026,55,5400,0.007054455,0.587442092,0.395315215,0.872542493,0.026953008,DB0020710018964_,3.613660359,-0.531977605,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,17543,DB00404,10018964,40,19852,24,9838,0.506413006,0.825965497,0.485587681,1.433228989,0.66720519,DB0040410018964_,0.404657649,-0.191202278,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,17547,DB00761,10018964,67,15240,39,8586,0.919300514,0.967843524,0.642068546,1.476802765,0.964315349,DB0076110018964_,0.036336912,-0.032684853,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,17550,DB01075,10018964,30,19918,29,11068,0.040484203,0.57482093,0.33317411,0.993138542,0.106609955,DB0107510018964_,2.238578382,-0.553696712,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,17551,DB01136,10018964,23,9861,42,11073,0.0624244,0.614942046,0.352740458,1.047027462,0.147975413,DB0113610018964_,1.910709149,-0.486227249,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,17552,DB01137,10018964,32,7740,24,5569,0.892666828,0.959323348,0.546928525,1.704086925,0.9552998,DB0113710018964_,0.045730061,-0.041527089,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,17553,DB00207,10021097,75,9005,74,5381,0.00279676,0.60568003,0.432575387,0.848199254,0.012759324,DB0020710021097_,4.361492997,-0.501403436,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,azithromycin,DB00207
,17554,DB00404,10021097,273,19619,148,9714,0.375864047,0.913323625,0.743830818,1.124989108,0.545667697,DB0040410021097_,0.605745103,-0.090664998,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,alprazolam,DB00404
,17555,DB00502,10021097,44,1350,44,1828,0.18957192,1.353929554,0.86546125,2.118209932,0.336001208,DB0050210021097_,1.090640523,0.303011145,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,haloperidol,DB00502
,17556,DB00531,10021097,180,7072,212,6304,0.007547161,0.756870859,0.615158308,0.930381634,0.028424865,DB0053110021097_,3.560491001,-0.278562636,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,cyclophosphamide,DB00531
,17557,DB00541,10021097,134,3000,144,4153,0.041032618,1.288141665,1.00552926,1.649368294,0.107719586,DB0054110021097_,2.228223855,0.25320061,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,vincristine,DB00541
,17558,DB00761,10021097,405,14902,311,8314,3.83624704826551e-05,0.726575564,0.623627642,0.847091783,0.000352203,DB0076110021097_,7.951302499,-0.319412791,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,potassium chloride,DB00761
,17559,DB00818,10021097,87,1333,124,1553,0.174120988,0.817461685,0.608013582,1.09518805,0.316326514,DB0081810021097_,1.150980326,-0.201551246,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,propofol,DB00818
,17560,DB01075,10021097,292,19656,278,10819,1.65674485152804e-10,0.578118226,0.488045427,0.685001301,5.21839885229652e-09,DB0107510021097_,19.07107522,-0.547976888,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,diphenhydramine,DB01075
,17563,DB00404,10028596,93,19799,74,9788,0.002886632,0.621297017,0.452463592,0.855783264,0.013096596,DB0040410028596_,4.335402947,-0.475946023,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,alprazolam,DB00404
,17569,DB01075,10028596,66,19882,47,11050,0.201746451,0.780479328,0.528388306,1.160750407,0.351145065,DB0107510028596_,1.046555852,-0.247847026,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,17570,DB01137,10028596,34,7738,21,5572,0.681560815,1.165809942,0.656629388,2.116382862,0.807446975,DB0113710028596_,0.213877892,0.153416075,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,levofloxacin,DB01137
,17571,DB00073,10033425,76,7330,45,6362,0.044024627,1.465810574,0.999151122,2.172478154,0.113635892,DB0007310033425_,2.174755874,0.382408382,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,rituximab,DB00073
,17576,DB00207,10035598,41,9039,43,5412,0.012467761,0.570938313,0.36242792,0.898090308,0.042441895,DB0020710035598_,3.15961932,-0.560474108,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,17577,DB00404,10035598,68,19824,50,9812,0.039190404,0.673131666,0.460005454,0.99094287,0.103999978,DB0040410035598_,2.263364594,-0.395814328,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,17579,DB00761,10035598,208,15099,100,8525,0.209647644,1.174405362,0.919356821,1.508357778,0.360749299,DB0076110035598_,1.019572024,0.160761944,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,17582,DB01075,10035598,100,19848,68,11029,0.197719182,0.817183525,0.593992111,1.130003795,0.346227555,DB0107510035598_,1.060659047,-0.201891577,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,17583,DB01136,10035598,80,9804,88,11027,0.938181164,1.022499402,0.744864491,1.401894152,0.978031724,DB0113610035598_,0.022213172,0.022250024,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,17584,DB01137,10035598,44,7728,55,5538,0.007526868,0.573329916,0.376101721,0.8694307,0.02836876,DB0113710035598_,3.562466732,-0.556293958,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,17586,DB00207,10037423,39,9041,19,5436,0.498917804,1.2341123,0.695384452,2.263586885,0.660807461,DB0020710037423_,0.414292765,0.210351926,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,17587,DB00316,10037423,217,65257,142,36811,0.169192305,0.862036119,0.694200148,1.073226288,0.30981363,DB0031610037423_,1.171784356,-0.148458107,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,17588,DB00404,10037423,82,19810,66,9796,0.00377004,0.614372223,0.438451883,0.863731329,0.016259826,DB0040410037423_,4.119057903,-0.487154308,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,17590,DB00531,10037423,50,7202,32,6484,0.149268983,1.40668916,0.883708462,2.268725977,0.282960856,DB0053110037423_,1.262446708,0.34123883,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclophosphamide,DB00531
,17592,DB00761,10037423,153,15154,74,8551,0.297794835,1.166694183,0.877097542,1.563512849,0.463691238,DB0076110037423_,0.768536384,0.154174265,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,17595,DB01075,10037423,73,19875,81,11016,2.11281980609595e-05,0.499521185,0.35867941,0.694659687,0.000209291,DB0107510037423_,8.471783098,-0.694105269,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,17596,DB01136,10037423,113,9771,110,11005,0.281413304,1.156999508,0.880632803,1.520532872,0.445344453,DB0113610037423_,0.808907246,0.145830023,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,17597,DB01137,10037423,43,7729,24,5569,0.384958397,1.290930215,0.764989763,2.226823446,0.555053838,DB0113710037423_,0.588690165,0.255363055,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,17598,DB00207,10037660,232,8848,161,5294,0.154282,0.8621997,0.700020619,1.064004425,0.289884781,DB0020710037660_,1.23827174,-0.148268365,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,17599,DB00502,10037660,21,1373,34,1838,0.582865303,0.826876073,0.453863873,1.473758943,0.730980223,DB0050210037660_,0.313368874,-0.190100446,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,haloperidol,DB00502
,17600,DB00818,10037660,41,1379,42,1635,0.576922354,1.157355341,0.729303315,1.835448653,0.72616023,DB0081810037660_,0.319984586,0.146137524,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,propofol,DB00818
,17601,DB01136,10037660,148,9736,175,10940,0.653727804,0.950288693,0.756928343,1.19177226,0.787753851,DB0113610037660_,0.23856961,-0.050989453,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,17602,DB00073,10043071,62,7344,72,6335,0.097942722,0.7428231,0.519353783,1.059829632,0.207782441,DB0007310043071_,1.571263702,-0.297297352,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,rituximab,DB00073
,17603,DB00207,10043071,31,9049,36,5419,0.007605473,0.515688505,0.308103224,0.858625688,0.028603501,DB0020710043071_,3.554226173,-0.662252369,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,azithromycin,DB00207
,17604,DB00404,10043071,118,19774,53,9809,0.56968743,1.104417934,0.791429491,1.559032951,0.720521308,DB0040410043071_,0.32778029,0.09931844,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,alprazolam,DB00404
,17605,DB00502,10043071,19,1375,41,1831,0.087657108,0.617187631,0.336738156,1.093379891,0.19125681,DB0050210043071_,1.654138197,-0.482582199,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,haloperidol,DB00502
,17606,DB00531,10043071,94,7158,82,6434,0.879356488,1.030397081,0.756531018,1.405754727,0.949348846,DB0053110043071_,0.051978954,0.029944243,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,cyclophosphamide,DB00531
,17607,DB00541,10043071,92,3042,80,4217,0.002899816,1.594059985,1.163975064,2.186949847,0.013140535,DB0054110043071_,4.332053578,0.466284212,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,vincristine,DB00541
,17608,DB00761,10043071,112,15195,65,8560,0.875209608,0.970663321,0.707929618,1.340370506,0.946235791,DB0076110043071_,0.05526349,-0.029775605,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,17609,DB00818,10043071,59,1361,76,1601,0.659049307,0.913266088,0.633585697,1.311020464,0.791749239,DB0081810043071_,0.233510554,-0.090727997,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,propofol,DB00818
,17611,DB01075,10043071,255,19693,129,10968,0.391662551,1.100954609,0.886162913,1.373282659,0.561516862,DB0107510043071_,0.577113476,0.09617763,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,17612,DB01136,10043071,43,9841,23,11092,0.004161387,2.107135339,1.240905467,3.665869799,0.017640628,DB0113610043071_,4.037550624,0.745329366,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,carvedilol,DB01136
,17613,DB01137,10043071,43,7729,63,5530,0.00032862,0.488368373,0.322960335,0.732357111,0.002174668,DB0113710043071_,6.130879447,-0.716685296,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,levofloxacin,DB01137
,17614,DB00316,10055798,242,65232,187,36766,0.00147493,0.729415319,0.599898641,0.887936447,0.007583827,DB0031610055798_,4.881737322,-0.315511999,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,17618,DB00761,10055798,92,15215,45,8580,0.475769911,1.152914586,0.797873324,1.687244964,0.641329886,DB0076110055798_,0.444211312,0.142293159,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,potassium chloride,DB00761
,17621,DB01075,10055798,54,19894,33,11064,0.656001805,0.910064477,0.579138812,1.449822602,0.789587299,DB0107510055798_,0.236244876,-0.094239828,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,diphenhydramine,DB01075
,17622,DB01136,10055798,63,9821,72,11043,0.931357092,0.983873143,0.689501351,1.400881579,0.972402581,DB0113610055798_,0.027985383,-0.01625831,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,carvedilol,DB01136
,17624,DB00073,10012735,235,7171,203,6204,1,1.001529737,0.82386948,1.218317723,1,DB0007310012735_,0,0.001528568,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,rituximab,DB00073
,17633,DB00327,10002855,140,5998,55,4207,0.0002226,1.785283319,1.294551207,2.491641325,0.001576672,DB0032710002855_,6.452438965,0.579577125,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,hydromorphone,DB00327
,17634,DB00433,10002855,102,7554,52,5968,0.011174335,1.549652809,1.097066892,2.211795769,0.038897814,DB0043310002855_,3.246817223,0.438030912,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,prochlorperazine,DB00433
,17635,DB01075,10002855,345,19603,106,10991,1.91159010372959e-08,1.824819407,1.461850307,2.293521024,4.01647848733271e-07,DB0107510002855_,14.72769013,0.601481027,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,17637,DB00327,10008190,43,6095,15,4247,0.022120617,1.997363647,1.086107608,3.875995509,0.066912989,DB0032710008190_,2.704362175,0.691828134,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,17638,DB00433,10008190,54,7602,49,5971,0.486468322,0.865610291,0.576102499,1.303409915,0.650348135,DB0043310008190_,0.430247467,-0.144320483,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,17639,DB01075,10008190,86,19862,67,11030,0.042185076,0.712848868,0.511448917,0.997091115,0.110047115,DB0107510008190_,2.206846684,-0.338485848,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,17644,DB01075,10022116,40,19908,20,11077,0.787887748,1.112828827,0.635001571,2.010382878,0.885095921,DB0107510022116_,0.122059255,0.106905266,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,17646,DB00433,10033371,232,7424,142,5878,0.017431407,1.293548604,1.042182898,1.610032326,0.055470283,DB0043310033371_,2.891907847,0.257389297,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,17647,DB01075,10033371,717,19231,271,10826,1.9731745182159e-08,1.489397537,1.290708851,1.722578554,4.13595631669099e-07,DB0107510033371_,14.69837708,0.398371701,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,17659,DB00112,10061822,48,5885,30,4061,0.729305601,1.104108224,0.68412424,1.808067938,0.842281112,DB0011210061822_,0.171641458,0.099037972,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,17660,DB00072,10013968,212,3511,24,311,0.272098834,0.782498632,0.502351081,1.268439956,0.434990746,DB0007210013968_,0.832430523,-0.245263105,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trastuzumab,DB00072
,17664,DB00072,10035598,55,3668,6,329,0.636267102,0.822244663,0.350892917,2.354903929,0.773906548,DB0007210035598_,0.256304152,-0.195717284,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trastuzumab,DB00072
,17665,DB00112,10035598,88,5845,46,4045,0.132892435,1.323874406,0.914355245,1.939105528,0.259795297,DB0011210035598_,1.347861278,0.280562593,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bevacizumab,DB00112
,17677,DB00112,10003549,255,5678,195,3896,0.280333627,0.897293654,0.738308026,1.091783932,0.444184061,DB0011210003549_,0.811516252,-0.108372098,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,17678,DB00958,10003549,172,4422,98,2487,0.948492228,0.98709354,0.761901565,1.284714385,0.986921529,DB0095810003549_,0.013164747,-0.012990472,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,17679,DB01229,10003549,215,5526,77,2632,0.035155291,1.329898309,1.015985367,1.755970098,0.095732384,DB0122910003549_,2.346198652,0.28510248,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,17680,DB00112,10016256,650,5283,440,3651,0.768978657,1.020920057,0.896509261,1.163345421,0.873452361,DB0011210016256_,0.135301689,0.020704238,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,17681,DB00958,10016256,382,4212,167,2418,0.004734974,1.313100668,1.084165861,1.595590897,0.019576687,DB0095810016256_,3.933415884,0.272391263,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,17685,DB00072,10003549,123,3600,11,324,1,1.006362112,0.535940171,2.090561854,1,DB0007210003549_,0,0.006341959,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,trastuzumab,DB00072
,17686,DB00682,10003549,791,18668,576,15788,0.007251818,1.161398618,1.039629335,1.298011111,0.027527481,DB0068210003549_,3.592570482,0.149624984,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,17687,DB00997,10003549,116,5215,78,3436,0.882390969,0.979850447,0.72656969,1.32735345,0.950859822,DB0099710003549_,0.050388628,-0.020355324,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,17688,DB00072,10011224,102,3621,9,326,1,1.020339664,0.510481923,2.316846181,1,DB0007210011224_,0,0.020135576,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trastuzumab,DB00072
,17689,DB00112,10011224,145,5788,99,3992,1,1.010170108,0.774406874,1.322149086,1,DB0011210011224_,0,0.010118741,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bevacizumab,DB00112
,17690,DB00997,10011224,81,5250,65,3449,0.233778932,0.818689378,0.581625939,1.156168993,0.390547808,DB0099710011224_,0.940204889,-0.200050537,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxorubicin,DB00997
,17692,DB00112,10013573,117,5816,78,4013,0.883060334,1.034989524,0.768241503,1.400748227,0.951117766,DB0011210013573_,0.050117391,0.034391304,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,bevacizumab,DB00112
,17693,DB00343,10013573,402,8334,175,4920,0.000930502,1.356092674,1.128595531,1.634708906,0.005190076,DB0034310013573_,5.261006986,0.304607531,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,17694,DB00997,10013573,82,5249,46,3468,0.413349312,1.177710507,0.808805814,1.73329035,0.58277076,DB0099710013573_,0.539961378,0.163572306,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,doxorubicin,DB00997
,17696,DB00112,10013786,40,5893,34,4057,0.406343412,0.809957711,0.498925542,1.321660025,0.575936187,DB0011210013786_,0.551758411,-0.210773241,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,bevacizumab,DB00112
,17697,DB00316,10013786,305,65169,135,36818,0.019286883,1.27641669,1.038507269,1.575563024,0.060093609,DB0031610013786_,2.811851778,0.244056691,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,17699,DB00682,10013786,74,19385,40,16324,0.023792719,1.557851903,1.045905959,2.35089195,0.070761669,DB0068210013786_,2.648437826,0.443307887,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,17703,DB00316,10019974,295,65179,117,36836,0.000993584,1.424949365,1.145996514,1.781412167,0.005471684,DB0031610019974_,5.208168929,0.35413628,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,17707,DB00112,10030124,101,5832,71,4020,0.937667759,0.98054942,0.714675179,1.351474688,0.977582109,DB0011210030124_,0.022672992,-0.019642232,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,17708,DB00316,10030124,656,64818,369,36584,0.973933807,1.003397532,0.881331851,1.143751193,1,DB0031610030124_,0,0.003391774,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,17709,DB00343,10030124,222,8514,92,5003,0.005335347,1.417919184,1.104157905,1.833087074,0.02154318,DB0034310030124_,3.837695974,0.349190433,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,17711,DB00112,10041349,36,5897,32,4059,0.322484438,0.774384719,0.46668569,1.290151841,0.490822434,DB0011210041349_,0.711672858,-0.255686477,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,bevacizumab,DB00112
,17712,DB00343,10041349,115,8621,42,5053,0.007744924,1.604819342,1.115911987,2.347060959,0.029027414,DB0034310041349_,3.539514579,0.473011191,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,17713,DB00682,10041349,201,19258,113,16251,0.000508007,1.500999787,1.185004039,1.908976816,0.003128987,DB0068210041349_,5.767045816,0.406131411,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,17718,DB00682,10046543,34,19425,18,16346,0.125588451,1.589462548,0.872454161,2.990638174,0.249468539,DB0068210046543_,1.38842247,0.463395939,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,warfarin,DB00682
,17722,DB00316,10060800,299,65175,82,36871,8.32047563738743e-10,2.062803756,1.610033767,2.667905247,2.3529177205888e-08,DB0031610060800_,17.5650246,0.724066104,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,17724,DB00682,10060800,100,19359,25,16339,2.35467848344342e-09,3.375781421,2.159181294,5.466410219,6.0649411011573e-08,DB0068210060800_,16.61815591,1.21662683,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,warfarin,DB00682
,17726,DB00541,10012735,107,3027,129,4168,0.316044758,1.142090489,0.8716258,1.494015883,0.483713998,DB0054110012735_,0.72626146,0.132860345,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,vincristine,DB00541
,17727,DB00675,10012735,69,1285,6,95,0.641736906,0.850296035,0.358138752,2.459195585,0.778362657,DB0067510012735_,0.250562723,-0.162170713,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,tamoxifen,DB00675
,17732,DB00635,10013911,94,32959,78,23716,0.354095264,0.867167443,0.635119521,1.186815945,0.52396172,DB0063510013911_,0.646336651,-0.142523191,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,17743,DB00541,10033371,56,3078,33,4264,8.52082359057655e-05,2.350580813,1.498203914,3.741426581,0.000696107,DB0054110033371_,7.270007687,0.854662452,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,vincristine,DB00541
,17744,DB00635,10033371,1561,31492,558,23236,8.62896972923508e-52,2.064047105,1.869788198,2.281042793,5.40029688887962e-49,DB0063510033371_,111.1402156,0.72466867,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,17747,DB00541,10047700,148,2986,240,4057,0.101828601,0.83786889,0.674250686,1.038504768,0.213680726,DB0054110047700_,1.543272312,-0.176893647,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,vincristine,DB00541
,17750,DB00073,10070863,49,7357,38,6369,0.666701485,1.116275272,0.714872129,1.755054925,0.797390387,DB0007310070863_,0.2264109,0.109997493,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,rituximab,DB00073
,17751,DB00531,10070863,88,7164,68,6448,0.375349769,1.164764597,0.837541096,1.625674694,0.545239831,DB0053110070863_,0.606529524,0.152519004,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclophosphamide,DB00531
,17756,DB00005,10037383,62,128020,37,42382,0.007022895,0.554756948,0.363341657,0.857681223,0.026856303,DB0000510037383_,3.617254742,-0.589225192,NA,10037383,Pulmonary fibrosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,17757,DB00005,10043607,164,127918,91,42328,0.0001147,0.596348658,0.458681456,0.779414799,0.000896972,DB0000510043607_,7.016486224,-0.516929786,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,etanercept,DB00005
,17758,DB00005,10056342,117,127965,30,42389,0.251642192,1.291879799,0.858693863,1.999774525,0.411638688,DB0000510056342_,0.887609285,0.256098366,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,17759,DB00112,10003239,142,5791,67,4024,0.010297073,1.472656447,1.090570699,2.005402151,0.03642045,DB0011210003239_,3.312624842,0.387067877,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,bevacizumab,DB00112
,17761,DB00399,10003239,341,6651,99,4899,9.0800183870103e-18,2.536890269,2.016158272,3.216106839,7.61302339083144e-16,DB0039910003239_,34.8115011,0.930939028,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,17762,DB00441,10003239,53,2221,21,1873,0.003042644,2.127951374,1.25655364,3.728578685,0.013674599,DB0044110003239_,4.292215235,0.755159721,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,gemcitabine,DB00441
,17764,DB00544,10003239,30,2405,24,2629,0.275124355,1.366332616,0.769827954,2.449620126,0.438440867,DB0054410003239_,0.824530329,0.312130228,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fluorouracil,DB00544
,17765,DB00958,10003239,96,4498,29,2556,0.002503349,1.880961103,1.226472232,2.964930736,0.011670958,DB0095810003239_,4.450651743,0.631782871,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,carboplatin,DB00958
,17766,DB01248,10003239,80,2620,29,1345,0.123538408,1.416048139,0.910213716,2.258704682,0.246457975,DB0124810003239_,1.400563787,0.347869991,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,docetaxel,DB01248
,17768,DB00399,10011906,399,6593,321,4677,0.109931334,0.881774894,0.755645127,1.02955302,0.225981314,DB0039910011906_,1.487302963,-0.125818477,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,17770,DB00441,10012735,142,2132,83,1811,0.008802193,1.453122085,1.092230482,1.943232105,0.032141399,DB0044110012735_,3.43761038,0.373714404,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,gemcitabine,DB00441
,17771,DB00958,10012735,353,4241,112,2473,1.421081994198e-08,1.837713767,1.472683912,2.307272035,3.0832142152286e-07,DB0095810012735_,14.99212302,0.608522281,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,carboplatin,DB00958
,17772,DB01248,10012735,316,2384,73,1301,8.89427213210307e-12,2.361855233,1.808229027,3.118102569,3.42543506215867e-10,DB0124810012735_,21.79462244,0.859447426,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,docetaxel,DB01248
,17786,DB00112,10028391,54,5879,32,4059,0.511103498,1.165040911,0.737394847,1.868067571,0.671432414,DB0011210028391_,0.398341917,0.152756203,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bevacizumab,DB00112
,17788,DB00399,10028391,78,6914,38,4960,0.058027047,1.472479918,0.985115393,2.234963634,0.13973806,DB0039910028391_,1.967985611,0.386947998,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,17794,DB00112,10028813,550,5383,297,3794,0.000389316,1.305171149,1.124256011,1.517422687,0.002507822,DB0011210028813_,5.988340775,0.266334181,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,17798,DB00399,10028836,80,6912,23,4975,4.82611828592082e-05,2.503325526,1.555389018,4.178269611,0.000428707,DB0039910028836_,7.754735927,0.917620058,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,17804,DB00112,10029331,139,5794,82,4009,0.268728894,1.172849684,0.883601824,1.565168121,0.43116368,DB0011210029331_,0.841267493,0.159436415,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,bevacizumab,DB00112
,17806,DB00399,10029331,269,6723,188,4810,0.84661112,1.023708593,0.843285551,1.244718081,0.922995277,DB0039910029331_,0.080131162,0.023431909,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,zoledronic acid,DB00399
,17807,DB00441,10029331,51,2223,32,1862,0.22151877,1.334842839,0.837576248,2.15606386,0.375374455,DB0044110029331_,0.979831204,0.288813561,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,gemcitabine,DB00441
,17809,DB00544,10029331,97,2338,106,2547,1,0.996897585,0.7445656,1.333558831,1,DB0054410029331_,0,-0.003107237,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,fluorouracil,DB00544
,17810,DB00958,10029331,154,4440,45,2540,4.72807727042654e-05,1.957590924,1.390615665,2.803595258,0.000421351,DB0095810029331_,7.772044072,0.671714597,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,carboplatin,DB00958
,17811,DB01248,10029331,83,2617,46,1328,0.636990403,0.915640825,0.626997704,1.351342661,0.774381848,DB0124810029331_,0.255690184,-0.088131104,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,docetaxel,DB01248
,17820,DB00112,10047700,380,5553,200,3891,0.001469084,1.331296173,1.11318362,1.595862257,0.007558205,DB0011210047700_,4.885121486,0.286153034,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,17823,DB01248,10053762,213,2487,184,1190,5.02839341360873e-08,0.553964324,0.447093283,0.686839868,9.7292102227976e-07,DB0124810053762_,13.84296293,-0.590654991,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,docetaxel,DB01248
,17831,DB00441,10035664,52,2222,86,1808,5.71091917398778e-05,0.492071715,0.339862265,0.706599357,0.000494601,DB0044110035664_,7.611758468,-0.709130811,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,gemcitabine,DB00441
,17832,DB00530,10035664,47,1761,43,1225,0.231728586,0.760415837,0.488634387,1.185936861,0.387997953,DB0053010035664_,0.946755214,-0.273889842,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,erlotinib,DB00530
,17834,DB00958,10035664,100,4494,115,2470,1.5285090182641e-07,0.477975013,0.360211066,0.633397783,2.67044596510946e-06,DB0095810035664_,12.83326507,-0.738196822,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,carboplatin,DB00958
,17835,DB01248,10035664,27,2673,65,1309,3.1182748317218e-13,0.203513347,0.124214611,0.325123111,1.49842511794895e-11,DB0124810035664_,24.92402139,-1.592023688,male,10035664,Pneumonia,10021881,Infections and infestations,Infec,docetaxel,DB01248
,17846,DB01217,10028813,230,2524,11,257,0.012624415,2.128597781,1.147075477,4.382910877,0.042872447,DB0121710028813_,3.149525912,0.755463444,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,anastrozole,DB01217
,17847,DB00399,10033371,400,6592,153,4845,3.01810200505674e-12,1.921405289,1.584719536,2.339098142,1.25424207435441e-10,DB0039910033371_,22.79931946,0.65305684,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,17848,DB01217,10033371,114,2640,8,260,0.419579145,1.403270192,0.678124289,3.366585468,0.588541854,DB0121710033371_,0.530107235,0.338805364,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,anastrozole,DB01217
,17849,DB01217,10053762,102,2652,28,240,4.97960403940805e-06,0.329830773,0.210261328,0.531668928,5.89988245101828e-05,DB0121710053762_,9.737993038,-1.109175566,male,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,anastrozole,DB01217
,17852,DB00073,10003997,45,7361,42,6365,0.747099612,0.926472163,0.593899711,1.447886547,0.856056728,DB0007310003997_,0.155418634,-0.076371279,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,rituximab,DB00073
,17860,DB00530,10011224,61,1747,40,1228,0.758954398,1.071942151,0.702667118,1.650976677,0.865568244,DB0053010011224_,0.144369058,0.069472098,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,erlotinib,DB00530
,17861,DB00112,10013971,36,5897,36,4055,0.118515679,0.687678712,0.420248823,1.12524131,0.238958664,DB0011210013971_,1.431464694,-0.374433538,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bevacizumab,DB00112
,17865,DB00112,10037844,145,5788,108,3983,0.560039116,0.923910267,0.712742008,1.200601544,0.712690785,DB0011210037844_,0.338707634,-0.079140326,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,bevacizumab,DB00112
,17874,DB00650,10011906,160,1971,164,1850,0.452309728,0.915739402,0.724950422,1.156574646,0.619927062,DB0065010011906_,0.478153449,-0.088023451,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,leucovorin,DB00650
,17878,DB01101,10061822,73,7516,27,3881,0.167649625,1.396059909,0.884998725,2.262730759,0.30774987,DB0110110061822_,1.178467938,0.333653918,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,17892,DB01075,10000059,173,19775,73,11024,0.052517744,1.321120772,0.998274117,1.763340848,0.129739559,DB0107510000059_,2.042226228,0.278480446,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,17896,DB00072,10010774,77,3646,7,328,1,0.989579379,0.452798488,2.564515215,1,DB0007210010774_,0,-0.010475296,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,trastuzumab,DB00072
,17898,DB01075,10010774,344,19604,174,10923,0.309506179,1.101564595,0.913872067,1.331653338,0.476952843,DB0107510010774_,0.740337655,0.096731529,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,17900,DB00072,10011906,338,3385,86,249,7.54178351722548e-17,0.289235965,0.219543003,0.383465558,5.68825766858742e-15,DB0007210011906_,32.8003724,-1.240512437,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,trastuzumab,DB00072
,17905,DB01075,10013781,98,19850,22,11075,3.46651608376833e-05,2.485279237,1.551893998,4.1486217,0.000322254,DB0107510013781_,8.040169881,0.910385022,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,17911,DB00316,10022687,147,65327,66,36887,0.133574323,1.257664921,0.934232619,1.708499516,0.260726346,DB0031610022687_,1.344283905,0.229256764,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,17916,DB01075,10024264,103,19845,48,11049,0.349205286,1.19468864,0.839581609,1.7212485,0.518740906,DB0107510024264_,0.656350739,0.1778856,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,17920,DB00316,10027175,618,64856,242,36711,8.17168176930378e-07,1.445498347,1.243142168,1.685022099,1.19895425791878e-05,DB0031610027175_,11.33147574,0.368454139,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,17921,DB01075,10027175,113,19835,35,11062,0.001884765,1.80054547,1.221709326,2.713691686,0.00927301,DB0107510027175_,4.680647243,0.588089658,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,17932,DB01075,10030095,86,19862,42,11055,0.518760749,1.139700222,0.778633315,1.69123489,0.6779846,DB0107510030095_,0.388630705,0.130765265,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,17934,DB00072,10047700,173,3550,10,325,0.213950687,1.583651231,0.829575718,3.395312614,0.366173578,DB0007210047700_,1.004647802,0.459733086,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,trastuzumab,DB00072
,17938,DB01075,10053762,742,19206,490,10607,0.002939016,0.836316755,0.743257575,0.941652786,0.013287216,DB0107510053762_,4.320952888,-0.178747844,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,17940,DB00072,10061428,91,3632,8,327,1,1.024120392,0.492415533,2.465537517,1,DB0007210061428_,0,0.02383409,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,trastuzumab,DB00072
,17942,DB00316,10061428,1014,64460,661,36292,0.004053257,0.863695322,0.781625008,0.954856734,0.01727294,DB0031610061428_,4.058614147,-0.146535209,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,17943,DB01075,10061428,278,19670,171,10926,0.297981467,0.903042403,0.7426075,1.1006666,0.463889168,DB0107510061428_,0.768109618,-0.101985769,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,diphenhydramine,DB01075
,17945,DB00073,10013573,140,7266,105,6302,0.272429922,1.156423728,0.889368294,1.507476103,0.435400876,DB0007310013573_,0.831488119,0.14533225,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,rituximab,DB00073
,17946,DB00073,10017577,77,7329,30,6377,0.000127037,2.233076763,1.445004986,3.532822291,0.000978511,DB0007310017577_,6.92947876,0.803380349,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,17947,DB00073,10019211,231,7175,120,6287,2.89554526418897e-06,1.686687972,1.343405304,2.126530426,3.67678295986508e-05,DB0007310019211_,10.21088729,0.522766826,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,rituximab,DB00073
,17958,DB01238,10061920,68,5182,87,3415,4.59160043181337e-05,0.515119595,0.368299571,0.717928219,0.000410511,DB0123810061920_,7.798107971,-0.663356182,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,17966,DB00264,10020751,220,29387,127,24765,0.00064649,1.459815908,1.167317341,1.832071253,0.00383416,DB0026410020751_,5.563804782,0.378310338,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,metoprolol,DB00264
,17967,DB01076,10020751,198,25549,132,25451,0.000393005,1.494226978,1.19200006,1.878136599,0.002526015,DB0107610020751_,5.981112258,0.401609002,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,atorvastatin,DB01076
,17969,DB00112,10002034,352,5581,120,3971,1.15526363062391e-12,2.08696658,1.684682577,2.599974474,5.15553557401517e-11,DB0011210002034_,23.68836502,0.735711615,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,bevacizumab,DB00112
,17971,DB00544,10002034,62,2373,83,2570,0.237732881,0.809035529,0.569766459,1.143707772,0.39519408,DB0054410002034_,0.928378294,-0.211912446,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,fluorouracil,DB00544
,17972,DB00563,10002034,357,46289,185,15163,8.84249154251434e-07,0.632131751,0.527298877,0.759841473,1.28660332241898e-05,DB0056310002034_,11.2609198,-0.458657439,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,methotrexate,DB00563
,17983,DB00544,10016256,196,2239,192,2461,0.290403925,1.122024044,0.907118301,1.388011942,0.455649436,DB0054410016256_,0.786031546,0.115134236,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fluorouracil,DB00544
,17984,DB00675,10016256,132,1222,11,90,0.72810045,0.883898556,0.456010831,1.881120397,0.841402489,DB0067510016256_,0.172685149,-0.123412978,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tamoxifen,DB00675
,17985,DB00112,10028372,86,5847,69,4022,0.365251716,0.857367038,0.615614892,1.197742952,0.534854672,DB0011210028372_,0.625760211,-0.15388917,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,bevacizumab,DB00112
,17989,DB00563,10028372,234,46412,101,15247,0.026102305,0.761115763,0.599691668,0.971675738,0.075954731,DB0056310028372_,2.577617762,-0.272969814,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,17991,DB00563,10053762,1046,45600,502,14846,6.050754018959e-12,0.678384182,0.608313809,0.757267441,2.40247838955192e-10,DB0056310053762_,22.14935006,-0.388041511,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,17992,DB00675,10053762,61,1293,7,94,0.321646073,0.633762838,0.278982274,1.688643349,0.489915224,DB0067510053762_,0.713522915,-0.456080467,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tamoxifen,DB00675
,18000,DB00316,10000486,69,65405,40,36913,0.92061317,0.973530895,0.650041838,1.475696474,0.964812755,DB0031610000486_,0.035821232,-0.026825719,NA,10000486,Acidosis,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,18001,DB00316,10002974,23,65451,30,36923,0.002474578,0.432500289,0.239874724,0.770199215,0.011572688,DB0031610002974_,4.459107408,-0.838172285,NA,10002974,Apnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,18002,DB00316,10005470,46,65428,52,36901,0.000683882,0.498909061,0.328024055,0.75667742,0.004013865,DB0031610005470_,5.518000577,-0.695331443,NA,10005470,Blood creatine phosphokinase increased,10022891,Investigations,Inv,acetaminophen,DB00316
,18003,DB00813,10033295,201,10371,327,9841,1.70459264301984e-09,0.583286246,0.485774732,0.699008618,4.5166550021952e-08,DB0081310033295_,16.91290907,-0.539077226,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,18031,DB00783,10013573,404,16310,11,362,0.493457345,0.815172728,0.445399059,1.660998298,0.656120915,DB0078310013573_,0.421410186,-0.204355252,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,estradiol,DB00783
,18044,DB00213,10003239,483,18412,203,13218,8.40545775088252e-11,1.708077201,1.444512793,2.025581007,2.76344536562785e-09,DB0021310003239_,19.70678761,0.535368294,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,18045,DB00158,10003285,121,16694,32,8072,0.001761651,1.828296873,1.228344501,2.793530769,0.008757446,DB0015810003285_,4.737850932,0.603384863,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,18046,DB00213,10003285,66,18829,31,13390,0.062915968,1.514013313,0.973335729,2.402163359,0.148801664,DB0021310003285_,1.905140975,0.414763948,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,18047,DB00563,10003285,301,46345,68,15280,0.004391671,1.459372183,1.117612783,1.929160464,0.018418043,DB0056310003285_,3.994424519,0.378006331,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,18049,DB01611,10003285,75,11838,17,2344,0.575162004,0.87359439,0.509824949,1.581132569,0.7246849,DB0161110003285_,0.322018339,-0.135139096,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,18055,DB00213,10003988,390,18505,206,13215,0.000489003,1.351982788,1.137338116,1.610880736,0.003036844,DB0021310003988_,5.796936372,0.301572247,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,18056,DB00158,10013573,459,16356,188,7916,0.061275365,1.181610275,0.992818772,1.410814524,0.145780762,DB0015810013573_,1.925651413,0.166878148,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,18057,DB00213,10013573,650,18245,354,13067,4.06059904512117e-05,1.315037632,1.151215073,1.504078987,0.000369574,DB0021310013573_,7.903160741,0.273865283,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,18058,DB00563,10013573,656,45990,168,15180,0.003407124,1.288833984,1.085194454,1.537638251,0.014994768,DB0056310013573_,4.200053968,0.253737922,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,18059,DB00213,10019211,915,17980,302,13119,2.62290816122213e-35,2.21059742,1.934990327,2.531074333,8.01664430438647e-33,DB0021310019211_,73.90378815,0.793262805,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,18060,DB01611,10019211,597,11316,66,2295,9.91913868377232e-07,1.834419899,1.414658537,2.412555212,1.42084229047932e-05,DB0161110019211_,11.16167561,0.6067283,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,hydroxychloroquine,DB01611
,18061,DB00158,10023232,283,16532,62,8042,1.27169248701537e-09,2.220349798,1.679159694,2.975803849,3.465675170679e-08,DB0015810023232_,17.17777328,0.79766475,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,18062,DB00213,10023232,156,18739,70,13351,0.001124089,1.587768603,1.189146204,2.138266651,0.00606521,DB0021310023232_,5.105186085,0.462329636,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,18063,DB00158,10033775,168,16647,37,8067,4.12583541216406e-06,2.20024877,1.532011087,3.235511271,4.98953686720646e-05,DB0015810033775_,9.905582372,0.788570431,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,18064,DB00213,10033775,189,18706,70,13351,1.288302851079e-06,1.927019301,1.456075021,2.575161024,1.79406836771452e-05,DB0021310033775_,10.92843959,0.655974405,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,18065,DB00563,10033775,306,46340,67,15281,0.002095603,1.50601224,1.151987774,1.993658041,0.010109743,DB0056310033775_,4.594255635,0.409465257,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,18067,DB01611,10033775,118,11795,15,2346,0.126168183,1.564614621,0.909014426,2.889374718,0.250374142,DB0161110033775_,1.384798912,0.447639545,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,hydroxychloroquine,DB01611
,18068,DB00158,10037377,87,16728,64,8040,0.011337206,0.653358222,0.467165682,0.917963494,0.039337134,DB0015810037377_,3.235586309,-0.425629721,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,18069,DB00213,10037377,154,18741,121,13300,0.424493304,0.903225417,0.706449859,1.156993638,0.593342542,DB0021310037377_,0.521983404,-0.101783126,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,18070,DB00563,10037377,86,46560,79,15269,1.51825294731479e-10,0.357007794,0.259804947,0.49112071,4.81100406511986e-09,DB0056310037377_,19.15236003,-1.029997667,male,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,18071,DB01611,10037377,35,11878,17,2344,0.004089032,0.406331279,0.221185076,0.774794239,0.01739021,DB0161110037377_,4.051847847,-0.900586495,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxychloroquine,DB01611
,18072,DB00158,10050584,194,16621,46,8058,4.26021708816786e-06,2.044575141,1.474192864,2.888023152,5.1284545986944e-05,DB0015810050584_,9.878121099,0.715190013,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,18073,DB00563,10050584,283,46363,52,15296,4.55867627447369e-05,1.795415103,1.331043045,2.46395346,0.000408123,DB0056310050584_,7.803942851,0.58523625,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,18074,DB00213,10061225,34,18861,20,13401,0.581090275,1.207855359,0.675288082,2.215594661,0.729519888,DB0021310061225_,0.315368649,0.188846356,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,18075,DB00563,10061225,63,46583,18,15330,0.699374919,1.151810294,0.673130189,2.067629496,0.819274175,DB0056310061225_,0.199336483,0.141334873,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,18078,DB00402,10002855,54,1298,20,676,0.213364629,1.405942088,0.819940524,2.501245353,0.36546382,DB0040210002855_,1.006587991,0.340707603,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,eszopiclone,DB00402
,18079,DB00425,10002855,351,12344,126,7358,7.03369990659073e-07,1.660465686,1.348004649,2.056155754,1.04956458725369e-05,DB0042510002855_,11.46455007,0.507098097,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,18085,DB00425,10017885,77,12618,37,7447,0.331714222,1.228256086,0.818618849,1.872381351,0.500537233,DB0042510017885_,0.692073291,0.205595347,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,18086,DB01216,10017885,7,229,109,7006,0.101032031,1.964502886,0.762953979,4.25263675,0.212356717,DB0121610017885_,1.54948779,0.675239229,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,finasteride,DB01216
,18087,DB00402,10019211,79,1273,25,671,0.033058575,1.665258447,1.038808861,2.753215759,0.091419741,DB0040210019211_,2.39229384,0.509980335,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,eszopiclone,DB00402
,18088,DB01216,10019211,12,224,216,6899,0.083239558,1.710898468,0.85739827,3.111251449,0.183853769,DB0121610019211_,1.693614569,0.537018653,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,finasteride,DB01216
,18093,DB01216,10020772,8,228,200,6915,0.547770618,1.213121611,0.510329066,2.478213161,0.702363754,DB0121610020772_,0.353303841,0.193196881,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,finasteride,DB01216
,18112,DB00425,10040984,75,12620,33,7451,0.163643997,1.341826683,0.878912425,2.088944053,0.302307514,DB0042510040984_,1.196310521,0.294031882,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,18115,DB00425,10042209,73,12622,25,7459,0.020587469,1.725536406,1.081274451,2.839691301,0.063232854,DB0042510042209_,2.760931264,0.545537962,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,18118,DB00425,10043882,50,12645,31,7453,0.818647339,0.950659561,0.594893466,1.541009151,0.90321487,DB0042510043882_,0.101794803,-0.050599261,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,zolpidem,DB00425
,18121,DB00425,10047895,226,12469,171,7313,0.013622898,0.775158335,0.631292855,0.953159557,0.045542497,DB0042510047895_,3.089109379,-0.254687967,NA,10047895,Weight decreased,10022891,Investigations,Inv,zolpidem,DB00425
,18124,DB00425,10052904,60,12635,26,7458,0.218482426,1.362130209,0.845652864,2.251075474,0.371678893,DB0042510052904_,0.989724988,0.309049804,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,18127,DB00425,10057668,51,12644,32,7452,0.820106982,0.939312665,0.591568961,1.51181578,0.904243317,DB0042510057668_,0.100656799,-0.062606878,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,18140,DB01216,10012378,10,226,581,6534,0.027741797,0.497652526,0.23409559,0.939273262,0.079662766,DB0121610012378_,2.529952978,-0.697853185,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,finasteride,DB01216
,18142,DB01216,10016256,11,225,636,6479,0.019196852,0.498072866,0.243797545,0.914925753,0.059862649,DB0121610016256_,2.815702529,-0.697008895,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,finasteride,DB01216
,18147,DB01216,10028813,13,223,235,6880,0.094482974,1.706545731,0.881251067,3.036782123,0.202476013,DB0121610028813_,1.597133852,0.534471287,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,finasteride,DB01216
,18158,DB00451,10042209,232,47039,30,15389,1.17347923636585e-07,2.530086712,1.724129064,3.836712308,2.10043593652546e-06,DB0045110042209_,13.07336565,0.928253576,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,18160,DB00451,10049119,76,47195,11,15408,0.008465535,2.255477094,1.191767604,4.710347493,0.031166972,DB0045110049119_,3.468396343,0.813361522,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,18162,DB00451,10061284,76,47195,21,15398,0.556485856,1.180756322,0.720177642,2.016780038,0.709865827,DB0045110061284_,0.342679303,0.166155184,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,18165,DB00451,10069868,136,47135,31,15388,0.07211613,1.432206522,0.963358731,2.190619752,0.164975847,DB0045110069868_,1.801956198,0.359216278,NA,10069868,Device issue,10077536,Product issues,Prod,levothyroxine,DB00451
,18173,DB14726,10042361,20,1997,44,2804,0.098513404,0.638287207,0.355227376,1.109957069,0.208656311,DB1472610042361_,1.567066827,-0.448966929,NA,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,dabigatran,DB14726
,18177,DB00761,10012735,1219,14088,510,8115,2.8907916469873e-09,1.376787513,1.236012621,1.535189326,7.33086912118293e-08,DB0076110012735_,16.42858666,0.319752897,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,18178,DB01409,10012735,223,5808,137,3829,0.546389188,1.073111997,0.860027542,1.342828715,0.701067734,DB0140910012735_,0.355150772,0.070562836,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,tiotropium,DB01409
,18179,DB11089,10012735,578,9597,316,8091,9.70351404075921e-10,1.542041891,1.337716136,1.780124662,2.70617365051837e-08,DB1108910012735_,17.42514504,0.433107441,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,18180,DB00193,10047700,632,18688,198,8504,3.88953484802475e-06,1.452469124,1.233573785,1.71622278,4.73975074085909e-05,DB0019310047700_,9.956940917,0.373264952,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,18182,DB00682,10047700,844,18615,345,16019,6.41672860631509e-33,2.105104561,1.851736304,2.397453686,1.71232194331972e-30,DB0068210047700_,68.53970248,0.744365139,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,18183,DB00761,10047700,634,14673,161,8464,8.71537066767099e-23,2.271464395,1.90347298,2.723170444,1.16581943002408e-20,DB0076110047700_,45.89827765,0.820424731,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,18184,DB01409,10047700,155,5876,73,3893,0.016571519,1.406685172,1.05499979,1.890090159,0.05327573,DB0140910047700_,2.932274402,0.341235995,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,tiotropium,DB01409
,18185,DB00559,10043607,62,9597,23,3283,0.709604288,0.92214308,0.562176239,1.562179313,0.826770776,DB0055910043607_,0.190227797,-0.081054883,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,bosentan,DB00559
,18198,DB01101,10003239,95,7494,26,3882,0.003605016,1.892650971,1.213273686,3.049332185,0.015688383,DB0110110003239_,4.154834762,0.637978476,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,capecitabine,DB01101
,18199,DB01234,10003239,419,31206,273,32615,1.04540476389731e-09,1.604073558,1.372857815,1.876657135,2.89551783130041e-08,DB0123410003239_,17.35751678,0.472546368,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,18202,DB00441,10003549,122,2152,79,1815,0.081276557,1.302384528,0.966263614,1.76361325,0.180523429,DB0044110003549_,1.711894708,0.264196837,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,gemcitabine,DB00441
,18203,DB00515,10003549,81,1789,76,2075,0.220759466,1.236102701,0.886643647,1.724871516,0.374425718,DB0051510003549_,0.982361844,0.211963447,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,cisplatin,DB00515
,18204,DB01234,10003549,1111,30514,1078,31810,0.102821237,1.074355177,0.985649047,1.17111829,0.215231043,DB0123410003549_,1.536043208,0.071720646,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,18205,DB01248,10003549,118,2582,62,1312,0.871925536,0.967129637,0.699813626,1.347245166,0.943737786,DB0124810003549_,0.057906921,-0.033422731,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,18209,DB00072,10008531,129,3594,10,325,0.75470069,1.16651079,0.606245952,2.515417985,0.862276239,DB0007210008531_,0.148179597,0.154017062,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,trastuzumab,DB00072
,18210,DB00186,10008531,163,16738,73,9935,0.049631597,1.325331877,0.998475928,1.773575029,0.124327317,DB0018610008531_,2.084837539,0.281662901,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,18213,DB00441,10008531,33,2241,33,1861,0.457825528,0.830472653,0.494698647,1.39412862,0.625139948,DB0044110008531_,0.469779737,-0.185760279,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,gemcitabine,DB00441
,18214,DB00515,10008531,29,1841,34,2117,1,0.980815607,0.574006073,1.665890427,1,DB0051510008531_,0,-0.019370801,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,cisplatin,DB00515
,18216,DB01101,10008531,38,7551,16,3892,0.566115233,1.224089278,0.66549512,2.354668725,0.717539729,DB0110110008531_,0.331926962,0.202197121,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,18217,DB01248,10008531,42,2658,11,1363,0.05609179,1.957647284,0.986623566,4.230054056,0.136238468,DB0124810008531_,1.993348484,0.671743387,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,18218,DB00186,10011224,325,16576,137,9871,0.000665058,1.412663737,1.151595367,1.740481841,0.003930091,DB0018610011224_,5.53909262,0.345477097,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,18221,DB00515,10011224,37,1833,39,2112,0.72855638,1.093097086,0.674770794,1.767947271,0.841772878,DB0051510011224_,0.172245042,0.089015031,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cisplatin,DB00515
,18222,DB00889,10011224,43,737,26,491,0.800720903,1.101759063,0.652020525,1.894075417,0.892281272,DB0088910011224_,0.113973868,0.096908051,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,granisetron,DB00889
,18223,DB01101,10011224,88,7501,22,3886,0.001602324,2.072141739,1.284568662,3.478711105,0.008108102,DB0110110011224_,4.814891492,0.728582729,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,capecitabine,DB01101
,18224,DB01234,10011224,514,31111,450,32438,0.007748478,1.190937179,1.046309943,1.35596022,0.029029182,DB0123410011224_,3.539453684,0.174740543,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,18225,DB01248,10011224,76,2624,28,1346,0.142746093,1.392205794,0.886915079,2.242370552,0.273645801,DB0124810011224_,1.295920707,0.330889391,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docetaxel,DB01248
,18228,DB00441,10013573,44,2230,37,1857,1,0.990281152,0.622047541,1.584278948,1,DB0044110013573_,0,-0.009766385,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,gemcitabine,DB00441
,18229,DB00515,10013573,39,1831,50,2101,0.667696241,0.89505754,0.570484351,1.395287737,0.798169392,DB0051510013573_,0.225434433,-0.110867272,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,cisplatin,DB00515
,18231,DB01248,10013968,156,2544,83,1291,0.725039353,0.953808285,0.719741722,1.271264408,0.838750056,DB0124810013968_,0.175842524,-0.047292587,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docetaxel,DB01248
,18244,DB01101,10016256,615,6974,249,3659,0.000773045,1.29579747,1.11039645,1.515713472,0.004445306,DB0110110016256_,5.415906581,0.259126313,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,18245,DB01248,10016256,253,2447,148,1226,0.164354328,0.856517703,0.688216741,1.068752948,0.303236128,DB0124810016256_,1.193243476,-0.154880292,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,18247,DB00186,10016766,60,16841,35,9973,1,1.015175381,0.657749537,1.588486937,1,DB0018610016766_,0,0.015061387,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,18254,DB01234,10016766,113,31512,107,32781,0.499904945,1.098594252,0.835459079,1.445440126,0.661587412,DB0123410016766_,0.413113162,0.094031409,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,18262,DB01101,10022437,67,7522,23,3885,0.094522141,1.504493342,0.922932672,2.536485162,0.202511674,DB0110110022437_,1.596957744,0.408456192,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,capecitabine,DB01101
,18263,DB01234,10022437,480,31145,440,32448,0.054133526,1.136545888,0.99558999,1.29770024,0.132709665,DB0123410022437_,2.019591508,0.12799374,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,18277,DB00186,10028391,97,16804,35,9973,0.011271614,1.644784826,1.106043759,2.497300097,0.039157012,DB0018610028391_,3.240175764,0.497609571,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,18283,DB01234,10028391,132,31493,79,32809,7.9652886150978e-05,1.740679771,1.306724477,2.331683015,0.000656645,DB0123410028391_,7.328366405,0.55427571,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,18285,DB00186,10028411,198,16703,60,9948,1.95853531893552e-06,1.965371681,1.463763755,2.672342119,2.59869262282788e-05,DB0018610028411_,10.55791698,0.675681378,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,18290,DB00695,10028411,421,27628,150,20378,1.78921020695523e-15,2.070107749,1.712513974,2.513455429,1.16698238932552e-13,DB0069510028411_,29.77918495,0.727600658,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,18292,DB01101,10028411,40,7549,16,3892,0.479759899,1.288925543,0.704783985,2.468620208,0.644617806,DB0110110028411_,0.439097686,0.253808959,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,capecitabine,DB01101
,18293,DB01234,10028411,145,31480,146,32742,0.814236698,1.032973217,0.814719742,1.309556271,0.900368592,DB0123410028411_,0.104951053,0.032441263,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,18294,DB01248,10028411,56,2644,15,1359,0.022704728,1.918638881,1.065479781,3.666870329,0.068216697,DB0124810028411_,2.685065916,0.651616018,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,docetaxel,DB01248
,18298,DB00186,10029331,261,16640,127,9881,0.071964757,1.220301649,0.98190633,1.523072479,0.164708402,DB0018610029331_,1.803578631,0.199098082,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,18301,DB00515,10029331,48,1822,47,2104,0.466642337,1.179293663,0.768059711,1.811573148,0.633314071,DB0051510029331_,0.456788818,0.164915668,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,cisplatin,DB00515
,18303,DB01234,10029331,1016,30609,1015,31873,0.367035669,1.042334903,0.953183483,1.13981315,0.536659763,DB0123410029331_,0.622390974,0.041463295,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,18305,DB00186,10029410,50,16851,18,9990,0.078127003,1.646757156,0.943525979,3.001098599,0.175241564,DB0018610029410_,1.741589893,0.498807994,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,18309,DB00695,10029410,57,27992,37,20491,0.602472369,1.127681856,0.732424201,1.755447693,0.746381968,DB0069510029410_,0.292517788,0.120164071,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,18312,DB01234,10029410,75,31550,85,32803,0.63493244,0.917418828,0.663152388,1.266957218,0.773095503,DB0123410029410_,0.257352689,-0.086191174,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,18316,DB00889,10033371,73,707,30,487,0.021028357,1.675508963,1.062698606,2.698673113,0.064315843,DB0088910033371_,2.743949284,0.516116978,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,granisetron,DB00889
,18317,DB01234,10033371,740,30885,508,32380,2.10743145241637e-13,1.527183777,1.360746216,1.715107237,1.03733774769222e-11,DB0123410033371_,25.29177845,0.423425371,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,18318,DB01248,10033371,155,2545,45,1329,0.000525785,1.798454746,1.273622227,2.582875051,0.003217753,DB0124810033371_,5.739071987,0.586927822,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,18319,DB00072,10037660,133,3590,11,324,1,1.091198834,0.582579734,2.262425051,1,DB0007210037660_,0,0.087276939,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,trastuzumab,DB00072
,18320,DB00186,10037660,467,16434,269,9739,0.727981351,1.028811662,0.881667683,1.202349859,0.841283351,DB0018610037660_,0.172826755,0.02840441,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,18323,DB00441,10037660,124,2150,115,1779,0.42214884,0.892223638,0.681071715,1.169520237,0.591215529,DB0044110037660_,0.525574643,-0.114038463,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,gemcitabine,DB00441
,18324,DB00889,10037660,55,725,33,484,0.735324211,1.112584138,0.69796398,1.797027977,0.847106124,DB0088910037660_,0.165929298,0.106685362,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,granisetron,DB00889
,18325,DB01101,10037660,112,7477,60,3848,0.808070483,0.960690574,0.694159546,1.340737924,0.89647291,DB0110110037660_,0.109287204,-0.040102905,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,18326,DB01248,10037660,98,2602,51,1323,0.929693777,0.97702103,0.684815679,1.408140182,0.971070968,DB0124810037660_,0.029355726,-0.023247102,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,18328,DB00186,10042128,156,16745,54,9954,0.000431949,1.717255379,1.251341899,2.388012464,0.002732884,DB0018610042128_,5.902397734,0.540727306,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,18331,DB00441,10042128,33,2241,21,1873,0.340090918,1.313294199,0.734652479,2.397323428,0.509245174,DB0044110042128_,0.674825701,0.272538636,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,gemcitabine,DB00441
,18333,DB00695,10042128,121,27928,50,20478,0.000467695,1.774419626,1.265631578,2.520479317,0.002920733,DB0069510042128_,5.835920667,0.573473398,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,18335,DB01101,10042128,196,7393,71,3837,0.010647957,1.432702427,1.083462046,1.912655384,0.037422321,DB0110110042128_,3.285487932,0.35956247,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,18336,DB01234,10042128,240,31385,188,32700,0.003577935,1.330072668,1.093630165,1.619525637,0.015593767,DB0123410042128_,4.160883975,0.285233578,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,18337,DB01248,10042128,57,2643,21,1353,0.227156506,1.389386474,0.825256899,2.423682518,0.382364238,DB0124810042128_,0.961381622,0.328862264,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,docetaxel,DB01248
,18339,DB00186,10042682,59,16842,23,9985,0.108486243,1.520799847,0.924341492,2.582141412,0.223765911,DB0018610042682_,1.497154814,0.419236412,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,18344,DB00695,10042682,144,27905,70,20458,0.004426208,1.50813954,1.125148205,2.037698032,0.018528888,DB0069510042682_,3.988424242,0.410876798,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,18347,DB01234,10042682,217,31408,123,32765,4.3671968865232e-08,1.840421273,1.467620986,2.316525731,8.54105432754929e-07,DB0123410042682_,13.97321119,0.609994498,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,18350,DB00186,10043607,94,16807,81,9927,0.014801806,0.685476467,0.503253497,0.935356985,0.048807058,DB0018610043607_,3.019880336,-0.377641111,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,lorazepam,DB00186
,18354,DB00695,10043607,285,27764,184,20344,0.1886467,1.134925051,0.938771437,1.374901208,0.334835472,DB0069510043607_,1.094115995,0.126566614,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,furosemide,DB00695
,18358,DB00186,10046306,120,16781,48,9960,0.020213823,1.483799975,1.052307711,2.121326332,0.062310349,DB0018610046306_,2.775627756,0.394606348,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,lorazepam,DB00186
,18363,DB00695,10046306,196,27853,77,20451,1.91648169499485e-06,1.86896074,1.427942951,2.467050338,2.55126469247606e-05,DB0069510046306_,10.57633627,0.625382523,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,18366,DB01234,10046306,176,31449,138,32750,0.012775265,1.328111205,1.056165787,1.672870888,0.043280676,DB0123410046306_,3.140049024,0.283757787,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,18375,DB00695,10050584,323,27726,106,20422,3.15280891706455e-14,2.244379827,1.795449313,2.824483415,1.72829160344195e-12,DB0069510050584_,27.08388771,0.808429237,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,18378,DB01234,10050584,210,31415,143,32745,9.23830987766322e-05,1.530683657,1.231066096,1.907838442,0.000745675,DB0123410050584_,7.201221074,0.42571447,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,18381,DB00186,10050819,37,16864,15,9993,0.251213701,1.461638092,0.782589728,2.868219231,0.411167978,DB0018610050819_,0.888753443,0.379557788,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,18384,DB00695,10050819,43,28006,25,20503,0.391462163,1.259193643,0.751629992,2.152062021,0.561325586,DB0069510050819_,0.577454175,0.23047155,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,18394,DB00695,10052264,57,27992,9,20519,1.01490853859818e-06,4.642389081,2.281010271,10.66996117,1.45140755914327e-05,DB0069510052264_,11.14039165,1.535229122,female,10052264,Catheter site erythema,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,18405,DB00695,10053156,35,28014,16,20512,0.121041322,1.601680674,0.863171312,3.100150336,0.242942208,DB0069510053156_,1.414931692,0.471053499,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,18408,DB01234,10053156,39,31586,16,32872,0.001121312,2.536772954,1.384941128,4.863412105,0.006052713,DB0123410053156_,5.107248739,0.930892783,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,18412,DB00441,10061428,91,2183,66,1828,0.414246535,1.154529024,0.826364579,1.620269416,0.583550575,DB0044110061428_,0.538624155,0.143692489,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,gemcitabine,DB00441
,18413,DB00515,10061428,45,1825,69,2082,0.128831793,0.74406981,0.496668683,1.105212069,0.253944033,DB0051510061428_,1.37064138,-0.295620417,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,cisplatin,DB00515
,18414,DB01234,10061428,594,31031,625,32263,0.839625097,0.988132184,0.880680882,1.108598623,0.917805277,DB0123410061428_,0.085770028,-0.011938801,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,18415,DB01248,10061428,80,2620,43,1331,0.771965594,0.945158527,0.640398729,1.411532365,0.87516403,DB0124810061428_,0.133343947,-0.056402612,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,docetaxel,DB01248
,18416,DB00186,10061818,318,16583,163,9845,0.140006405,1.158248289,0.954294812,1.410023959,0.269842069,DB0018610061818_,1.309918419,0.146908768,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,18418,DB00695,10061818,371,27678,252,20276,0.36934794,1.078517912,0.915607906,1.272050799,0.539031828,DB0069510061818_,0.61798066,0.075587795,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,18419,DB01234,10061818,461,31164,377,32511,0.000500245,1.275656462,1.109865728,1.466933242,0.003093142,DB0123410061818_,5.778567967,0.243460918,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,18442,DB01156,10040753,180,13442,33,6295,7.11038721609717e-08,2.554307841,1.752360631,3.828381852,1.32927829285287e-06,DB0115610040753_,13.5308744,0.937781283,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,bupropion,DB01156
,18446,DB01156,10057668,50,13572,27,6301,0.540470916,0.859766554,0.527545079,1.429599331,0.696010877,DB0115610057668_,0.362389991,-0.151094376,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,18476,DB00331,10022061,158,24788,43,20709,1.3538112300902e-12,3.069581235,2.177752115,4.409126259,5.98066019881023e-11,DB0033110022061_,23.53990506,1.121541147,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,18478,DB00060,10040047,82,9426,25,2440,0.471680191,0.849039738,0.535533869,1.390312849,0.637828677,DB0006010040047_,0.449685562,-0.163649288,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,interferon beta-1a,DB00060
,18479,DB01067,10040047,63,4298,64,4759,0.655202501,1.08994202,0.755383,1.572267864,0.788896166,DB0106710040047_,0.237120569,0.086124502,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,glipizide,DB01067
,18480,DB00060,10041349,51,9457,13,2452,1,1.017172003,0.544200617,2.042102952,1,DB0006010041349_,0,0.017026231,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,18481,DB00331,10041349,260,24686,207,20545,0.640796633,1.045350106,0.866705258,1.262050721,0.777660072,DB0033110041349_,0.251465776,0.044351859,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,metformin,DB00331
,18482,DB01067,10041349,47,4314,42,4781,0.337810762,1.24015409,0.798651401,1.931247422,0.506942758,DB0106710041349_,0.679357186,0.215235638,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,glipizide,DB01067
,18483,DB00331,10044565,222,24724,174,20578,0.577302082,1.061925823,0.866083705,1.303691655,0.726342542,DB0033110044565_,0.319733555,0.060084074,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,metformin,DB00331
,18484,DB01067,10044565,40,4321,39,4784,0.574224121,1.135522832,0.710544781,1.81600038,0.723994773,DB0106710044565_,0.322971107,0.12709319,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,glipizide,DB01067
,18485,DB00331,10048334,86,24860,37,20715,0.000727384,1.936726054,1.302355353,2.930950569,0.00422462,DB0033110048334_,5.466825912,0.660998946,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,18488,DB00331,10061422,34,24912,31,20721,0.710656588,0.912263811,0.543827533,1.535397112,0.827428337,DB0033110061422_,0.189432778,-0.091826064,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,metformin,DB00331
,18496,DB00073,10015090,30,7376,35,6372,0.261993595,0.740492081,0.438629385,1.243075889,0.42369346,DB0007310015090_,0.858745057,-0.30044034,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rituximab,DB00073
,18498,DB00073,10025482,169,7237,84,6323,1.87992005476471e-05,1.757735013,1.342083332,2.316782907,0.00018918,DB0007310025482_,8.57281399,0.564026056,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,18499,DB00215,10006093,59,11044,27,5249,0.908485075,1.038556757,0.647380803,1.705880632,0.959026229,DB0021510006093_,0.041836854,0.037832015,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,citalopram,DB00215
,18500,DB00338,10006093,68,33606,68,22204,0.017643253,0.660738358,0.464870116,0.939085347,0.056022336,DB0033810006093_,2.882004814,-0.414397345,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,omeprazole,DB00338
,18501,DB08868,10006093,144,9058,55,2456,0.036279169,0.709920964,0.515121819,0.990363454,0.098096694,DB0886810006093_,2.321801614,-0.342601634,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,fingolimod,DB08868
,18502,DB00215,10014387,76,11027,57,5219,0.011549769,0.631067421,0.44102269,0.907435667,0.039960185,DB0021510014387_,3.21987169,-0.460342574,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,citalopram,DB00215
,18503,DB00338,10014387,87,33587,47,22225,0.289347041,1.224850044,0.849054592,1.786567635,0.454493066,DB0033810014387_,0.788572622,0.202818424,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,omeprazole,DB00338
,18504,DB08868,10014387,41,9161,16,2495,0.255724425,0.697921413,0.382480266,1.334668209,0.416462256,DB0886810014387_,0.875959444,-0.359648771,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,fingolimod,DB08868
,18511,DB11089,10035226,132,10043,150,8257,0.007893897,0.723524286,0.567152399,0.922125752,0.029464795,DB1108910035226_,3.52455913,-0.323621165,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,docusate,DB11089
,18516,DB06700,10013754,55,2170,11,607,0.366630457,1.398451806,0.718354031,2.982201241,0.536276102,DB0670010013754_,0.623106135,0.335365772,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,desvenlafaxine,DB06700
,18520,DB00005,10023203,63,128019,18,42401,0.699708083,1.159226755,0.67762704,2.080602798,0.819545349,DB0000510023203_,0.199005545,0.147753192,NA,10023203,Joint destruction,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,18522,DB00136,10035664,58,2034,75,1607,0.005808363,0.61107753,0.423348664,0.878326526,0.023069328,DB0013610035664_,3.76925133,-0.492531438,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,calcitriol,DB00136
,18523,DB00727,10035664,145,3698,168,4005,0.564488396,0.934730743,0.739851956,1.179838881,0.71628014,DB0072710035664_,0.333683931,-0.067496766,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,nitroglycerin,DB00727
,18526,DB00727,10038695,31,3812,47,4126,0.17151999,0.71393635,0.437475749,1.150291339,0.312823575,DB0072710038695_,1.162115907,-0.336961467,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nitroglycerin,DB00727
,18528,DB00186,10003598,39,16862,34,9974,0.114377,0.678529046,0.417032474,1.108814691,0.232693456,DB0018610003598_,1.45803333,-0.387827991,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,18530,DB00338,10003598,48,33626,26,22246,0.476259101,1.221335788,0.742470746,2.051469134,0.641659905,DB0033810003598_,0.443696859,0.199945168,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,18552,DB00316,10062352,157,65317,51,36902,0.000490622,1.739204728,1.26028746,2.43538549,0.00304618,DB0031610062352_,5.793866997,0.553427956,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,18553,DB00338,10062352,84,33590,27,22245,0.00088055,2.060303157,1.321017152,3.308359182,0.004961472,DB0033810062352_,5.306052711,0.722853136,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,18554,DB00381,10062352,48,29312,24,22863,0.075590514,1.559959883,0.936576237,2.663702759,0.170761606,DB0038110062352_,1.767486813,0.444660105,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,18559,DB00635,10062352,113,32940,35,23759,5.18636706440939e-06,2.328653949,1.580741433,3.508138258,6.11316853309421e-05,DB0063510062352_,9.702480245,0.845290396,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,18568,DB00999,10011078,35,21395,58,12181,3.9224486493074e-07,0.343577417,0.219043752,0.531931329,6.21468129879717e-06,DB0099910011078_,11.98859611,-1.068342816,male,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,18574,DB00745,10020772,71,2506,36,1047,0.389671495,0.824057017,0.540463141,1.275712219,0.559590545,DB0074510020772_,0.580549933,-0.193515556,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,modafinil,DB00745
,18575,DB00745,10053762,70,2507,32,1051,0.741413596,0.917082594,0.591390046,1.449591719,0.85171349,DB0074510053762_,0.160505088,-0.086557741,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,modafinil,DB00745
,18576,DB00451,10061024,234,47037,106,15313,0.006503879,0.718676207,0.568476772,0.913527045,0.025255497,DB0045110061024_,3.678711448,-0.330344361,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,18578,DB00999,10061024,95,21335,67,12172,0.190636048,0.808960462,0.58504529,1.123962779,0.337374744,DB0099910061024_,1.086560965,-0.212005236,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,18581,DB00999,10062060,44,21386,19,12220,0.359359905,1.323235757,0.756257854,2.400975799,0.529105575,DB0099910062060_,0.636567292,0.280080068,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,18584,DB00316,10013950,353,65121,191,36762,0.654645042,1.043326676,0.872016859,1.251352663,0.78836941,DB0031610013950_,0.237788505,0.042414335,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,18585,DB00437,10013950,41,6880,66,11480,0.842050163,1.036584942,0.683484193,1.555661264,0.919538368,DB0043710013950_,0.083883508,0.035931601,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,18586,DB00497,10013950,97,19170,85,16290,0.881516479,0.969723082,0.716666498,1.314252863,0.95045981,DB0049710013950_,0.050809401,-0.030744731,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,18587,DB00787,10013950,63,16937,64,17184,1,0.998730615,0.693522702,1.437866955,1,DB0078710013950_,0,-0.001270192,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,18589,DB01075,10013950,125,19823,61,11036,0.443006191,1.140849488,0.832683809,1.577437811,0.611095131,DB0107510013950_,0.492502635,0.13177315,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,18591,DB00437,10016288,120,6801,225,11321,0.312474853,0.887778648,0.703862597,1.115282582,0.479951003,DB0043710016288_,0.734071258,-0.119032838,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,allopurinol,DB00437
,18592,DB00722,10016288,58,25345,85,25947,0.036284255,0.698568068,0.491227778,0.987359921,0.098098154,DB0072210016288_,2.321786731,-0.358722657,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,lisinopril,DB00722
,18593,DB00787,10016288,220,16780,320,16928,3.02608404211621e-05,0.693574428,0.580714182,0.82718733,0.000286014,DB0078710016288_,8.159468218,-0.365896722,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,acyclovir,DB00787
,18594,DB01075,10016288,147,19801,141,10956,4.30403978349274e-06,0.576832059,0.45417594,0.732928487,5.17528296930954e-05,DB0107510016288_,9.869031447,-0.550204113,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,diphenhydramine,DB01075
,18596,DB00437,10025197,17,6904,47,11499,0.091744156,0.602450988,0.324029045,1.069846845,0.198069415,DB0043710025197_,1.619137727,-0.506748965,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,allopurinol,DB00437
,18597,DB00497,10025197,38,19229,25,16350,0.37606756,1.292412015,0.75974702,2.234878467,0.545842558,DB0049710025197_,0.6054247,0.256510251,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,oxycodone,DB00497
,18598,DB00787,10025197,30,16970,31,17217,1,0.981825657,0.573853583,1.677547236,1,DB0078710025197_,0,-0.018341526,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,acyclovir,DB00787
,18599,DB00904,10025197,69,23000,38,14418,0.551906364,1.138287429,0.754914329,1.739622855,0.705792487,DB0090410025197_,0.348434012,0.129524878,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,ondansetron,DB00904
,18600,DB01075,10025197,78,19870,41,11056,0.848114406,1.058551247,0.715744574,1.586155027,0.924068361,DB0107510025197_,0.078969227,0.056901225,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,diphenhydramine,DB01075
,18611,DB00437,10030095,69,6852,77,11469,0.016110876,1.499824454,1.066296931,2.106272166,0.052105371,DB0043710030095_,2.954487249,0.405348071,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,18612,DB00787,10030095,62,16938,44,17204,0.079522576,1.431197817,0.956393211,2.157860892,0.177636117,DB0078710030095_,1.728018107,0.358511728,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,18643,DB06228,10019022,34,15878,50,16026,0.101065154,0.686349533,0.430193684,1.083080568,0.212409353,DB0622810019022_,1.549239956,-0.376368257,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,18645,DB00316,10042033,32,65442,38,36915,0.002524025,0.475015479,0.287248728,0.781002411,0.01174542,DB0031610042033_,4.444291919,-0.744407887,NA,10042033,Stevens-Johnson syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,18650,DB00230,10043607,102,19572,59,8592,0.102699512,0.758926227,0.544914578,1.065422189,0.215070444,DB0023010043607_,1.536789658,-0.275850704,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,pregabalin,DB00230
,18651,DB00399,10043607,79,6913,110,4888,4.8224070663279e-06,0.507828376,0.374538641,0.685920772,5.7278341499516e-05,DB0039910043607_,9.76758799,-0.67761173,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,zoledronic acid,DB00399
,18652,DB00451,10043607,370,46901,131,15288,0.434606836,0.920651906,0.751675361,1.133410179,0.603117083,DB0045110043607_,0.505643933,-0.082673267,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,18653,DB00497,10043607,147,19120,173,16202,0.003994033,0.720044902,0.573355856,0.903268685,0.017061003,DB0049710043607_,4.07095992,-0.328441705,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,oxycodone,DB00497
,18654,DB00230,10048592,52,19622,22,8629,1,1.039411774,0.619863427,1.798368169,1,DB0023010048592_,0,0.038654952,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,18656,DB00451,10048592,61,47210,17,15402,0.692981036,1.170636091,0.674681577,2.138697791,0.815002163,DB0045110048592_,0.204564511,0.157547268,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,18657,DB00480,10048592,98,67330,110,67552,0.445503629,0.893847716,0.673621946,1.184635569,0.613446516,DB0048010048592_,0.488662198,-0.112219858,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,18658,DB00497,10048592,30,19237,27,16348,0.894424683,0.944276477,0.542298305,1.651520962,0.955931269,DB0049710048592_,0.045069263,-0.057336277,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,18659,DB00999,10048592,35,21395,16,12223,0.560458485,1.24975016,0.673379113,2.419209233,0.713103628,DB0099910048592_,0.338128529,0.22294366,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,18660,DB00230,10051055,55,19619,43,8608,0.005741373,0.561239111,0.369400779,0.857548975,0.022860259,DB0023010051055_,3.7783553,-0.577608242,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,pregabalin,DB00230
,18661,DB00399,10051055,92,6900,116,4882,4.73101127892264e-05,0.561191156,0.421041157,0.746166044,0.000421541,DB0039910051055_,7.77159322,-0.577693691,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,zoledronic acid,DB00399
,18662,DB00451,10051055,247,47024,147,15272,1.93880562401165e-08,0.545723851,0.442770337,0.674533499,4.0720340253413e-07,DB0045110051055_,14.71395302,-0.605642198,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,18663,DB00480,10051055,833,66595,1101,66561,1.40037767342851e-09,0.756202732,0.68982531,0.828700067,3.77721161067915e-08,DB0048010051055_,17.09169468,-0.279445775,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,lenalidomide,DB00480
,18664,DB00497,10051055,112,19155,154,16221,9.48803145410133e-05,0.615891213,0.478015218,0.791516769,0.00076197,DB0049710051055_,7.179602869,-0.484684934,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,oxycodone,DB00497
,18665,DB00182,10000081,43,5151,22,2830,0.896548659,1.073839712,0.626861249,1.889041888,0.956301489,DB0018210000081_,0.044682051,0.071240741,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,amphetamine,DB00182
,18667,DB00182,10037844,100,5094,46,2806,0.337687047,1.19742933,0.833650885,1.742473607,0.506838187,DB0018210037844_,0.679563485,0.180177034,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,amphetamine,DB00182
,18687,DB00213,10041101,55,18840,34,13387,0.590544989,1.149400909,0.735755982,1.81922762,0.737112094,DB0021310041101_,0.305015304,0.139240858,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,18688,DB00497,10041101,62,19205,37,16338,0.105695937,1.425507045,0.93326854,2.20477791,0.219678313,DB0049710041101_,1.515591017,0.354527572,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,18694,DB00927,10041101,37,7460,18,4998,0.334422885,1.377132392,0.763406364,2.572641381,0.503526023,DB0092710041101_,0.686119885,0.32000336,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,18699,DB11089,10041101,45,10130,41,8366,0.665286047,0.906441255,0.579767414,1.420775738,0.796331598,DB1108910041101_,0.227739599,-0.098229056,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,18703,DB00203,10005734,165,13713,75,8863,0.011475256,1.421884676,1.074354903,1.896529812,0.03975316,DB0020310005734_,3.225065951,0.351983228,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,sildenafil,DB00203
,18704,DB06403,10005734,170,21301,57,6604,0.638048439,0.924651866,0.680310236,1.272805676,0.775273465,DB0640310005734_,0.254539454,-0.078337974,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,ambrisentan,DB06403
,18705,DB06403,10025482,1102,20369,282,6379,0.002842705,1.223797087,1.069421136,1.404008458,0.012938613,DB0640310025482_,4.34753915,0.201958392,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,18711,DB01267,10013709,199,2653,297,3418,0.131635972,0.863259272,0.712508973,1.044207163,0.25806836,DB0126710013709_,1.354530768,-0.147040202,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,18717,DB00207,10043607,45,9035,44,5411,0.021322235,0.612552033,0.394578122,0.951380579,0.065063263,DB0020710043607_,2.732395203,-0.490121389,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,azithromycin,DB00207
,18719,DB00421,10043607,72,8831,30,5222,0.122602181,1.41914881,0.913617112,2.254461364,0.245161662,DB0042110043607_,1.405837443,0.350057262,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,spironolactone,DB00421
,18720,DB00588,10043607,111,16413,79,8389,0.025778955,0.718137324,0.532685537,0.972104469,0.075201136,DB0058810043607_,2.587588937,-0.331094469,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,fluticasone propionate,DB00588
,18724,DB00588,10056342,54,16470,16,8452,0.057383925,1.731932362,0.975830601,3.244086413,0.138506563,DB0058810056342_,1.976837567,0.549237758,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,18725,DB00695,10056342,52,27997,28,20500,0.213121162,1.359830029,0.842765536,2.237004682,0.365176433,DB0069510056342_,1.007374664,0.307359713,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,18737,DB00316,10002198,190,65284,90,36863,0.19057435,1.19202007,0.922510443,1.549981101,0.337288947,DB0031610002198_,1.086815305,0.175649405,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,acetaminophen,DB00316
,18742,DB00316,10005750,550,64924,267,36686,0.044220352,1.164008236,1.003229787,1.353120166,0.114026778,DB0031610005750_,2.171321963,0.151869424,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,acetaminophen,DB00316
,18743,DB00761,10005750,121,15186,52,8573,0.111786307,1.313612337,0.94053454,1.856968507,0.228741822,DB0076110005750_,1.475161328,0.272780852,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,potassium chloride,DB00761
,18745,DB01075,10005750,200,19748,109,10988,0.905079209,1.020937157,0.803499561,1.302985319,0.957691196,DB0107510005750_,0.043229895,0.020720986,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,diphenhydramine,DB01075
,18749,DB00316,10015967,114,65360,45,36908,0.046961039,1.430537669,1.004493529,2.068177389,0.119378231,DB0031610015967_,2.125458413,0.358050366,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,acetaminophen,DB00316
,18750,DB00761,10015967,39,15268,11,8614,0.03927733,2.000244207,1.004020471,4.332663426,0.104193835,DB0076110015967_,2.261502318,0.693269277,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,potassium chloride,DB00761
,18752,DB01075,10015967,64,19884,25,11072,0.149894964,1.425468234,0.884556662,2.363977959,0.283779107,DB0107510015967_,1.259559136,0.354500345,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,diphenhydramine,DB01075
,18757,DB00761,10037844,370,14937,165,8460,0.01218581,1.270068222,1.05219868,1.538297481,0.041660143,DB0076110037844_,3.178210423,0.239070617,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,potassium chloride,DB00761
,18758,DB00958,10037844,139,4455,44,2541,0.000564442,1.801715742,1.270297939,2.599229666,0.003412227,DB0095810037844_,5.680390068,0.588739401,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,carboplatin,DB00958
,18759,DB01248,10037844,149,2551,36,1338,1.50487103197559e-05,2.170486598,1.489525202,3.236763659,0.000155424,DB0124810037844_,8.769350479,0.774951381,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,docetaxel,DB01248
,18762,DB00761,10042772,192,15115,110,8515,0.90404021,0.983291254,0.772591326,1.256597145,0.957450283,DB0076110042772_,0.043481484,-0.016849912,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,18763,DB01075,10042772,99,19849,58,11039,0.739340124,0.949290691,0.679106007,1.337481353,0.850111774,DB0107510042772_,0.16238744,-0.052040214,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,18766,DB06403,10008479,877,20594,164,6497,1.83552484454257e-10,1.686937702,1.422830673,2.010233531,5.75393804875391e-09,DB0640310008479_,18.97338134,0.522914874,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,18768,DB06403,10016326,60,21411,17,6644,0.893171772,1.095199983,0.630098541,2.003531194,0.955474763,DB0640310016326_,0.045546928,0.090936979,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,18769,DB06403,10019211,2669,18802,591,6070,4.63321616853175e-16,1.45796883,1.326835363,1.603837785,3.22606852953264e-14,DB0640310019211_,31.06492708,0.377044255,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,18770,DB00335,10022998,34,8432,19,5446,0.67392379,1.155798283,0.640071048,2.147255861,0.802250258,DB0033510022998_,0.220334677,0.144791259,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,atenolol,DB00335
,18771,DB00451,10022998,140,47131,41,15378,0.604209247,1.114130993,0.781229839,1.619827821,0.747617571,DB0045110022998_,0.2908637,0.108074723,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,18772,DB00641,10022998,30,14094,51,12424,0.004995153,0.518553072,0.318653234,0.830385316,0.02045612,DB0064110022998_,3.889473177,-0.6567129,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,18775,DB00641,10047899,216,13908,121,12354,4.54644429389436e-05,1.585632003,1.261674256,2.000442087,0.000407305,DB0064110047899_,7.805948257,0.460983068,NA,10047899,Weight increased,10022891,Investigations,Inv,simvastatin,DB00641
,18776,DB06626,10038389,11,677,53,1399,0.009320771,0.42903248,0.200715295,0.83781846,0.033639497,DB0662610038389_,3.392054383,-0.846222653,NA,10038389,Renal cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,axitinib,DB06626
,18778,DB06626,10061818,54,634,182,1270,0.001118359,0.594476515,0.423968097,0.822813888,0.006039253,DB0662610061818_,5.109475021,-0.520074068,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,axitinib,DB06626
,18781,DB00047,10012671,165,9120,117,8401,0.035300782,1.299053372,1.016865199,1.663913171,0.096058912,DB0004710012671_,2.342793607,0.261635824,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,insulin glargine,DB00047
,18782,DB00331,10012671,319,24627,310,20442,0.052876864,0.854167996,0.727415683,1.003080291,0.130448953,DB0033110012671_,2.036773294,-0.157627388,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,18783,DB06655,10012671,49,3639,48,2071,0.010296687,0.581055613,0.380678159,0.887239322,0.03642045,DB0665510012671_,3.312624842,-0.542908808,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,liraglutide,DB06655
,18785,DB00047,10033647,24,9261,35,8483,0.089445371,0.628130347,0.357141375,1.087430324,0.194391797,DB0004710033647_,1.637879585,-0.465007576,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,18786,DB00331,10033647,105,24841,112,20640,0.075377069,0.778962772,0.590736278,1.026502416,0.170455221,DB0033110033647_,1.769282649,-0.249792024,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,18787,DB06655,10033647,83,3605,67,2052,0.039046196,0.705209688,0.50247433,0.992746674,0.103742977,DB0665510033647_,2.265838812,-0.349260091,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,liraglutide,DB06655
,18789,DB00374,10003239,442,17274,125,5599,0.198180392,1.146110391,0.935400136,1.412580727,0.346861872,DB0037410003239_,1.058828642,0.136373941,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,18792,DB00374,10000059,397,17319,136,5588,0.540943202,0.941854717,0.771398763,1.155665597,0.696380256,DB0037410000059_,0.361859423,-0.059904244,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,18793,DB08931,10000059,313,6264,81,2365,0.002542216,1.458938153,1.133615249,1.895236112,0.011812296,DB0893110000059_,4.438614268,0.377708878,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,18800,DB00374,10018884,183,17533,68,5656,0.336813693,0.868177377,0.652649733,1.166303078,0.505894167,DB0037410018884_,0.681427787,-0.141359234,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,treprostinil,DB00374
,18801,DB08931,10018884,188,6389,60,2386,0.311267699,1.170131208,0.867077222,1.598377604,0.4787683,DB0893110018884_,0.736538514,0.157115887,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,riociguat,DB08931
,18802,DB00374,10047895,518,17198,170,5554,0.857072065,0.984031172,0.823648776,1.180342383,0.931434447,DB0037410047895_,0.071029465,-0.016097703,NA,10047895,Weight decreased,10022891,Investigations,Inv,treprostinil,DB00374
,18803,DB00559,10047895,177,9482,52,3254,0.35893326,1.16810267,0.850641799,1.627804865,0.528677528,DB0055910047895_,0.63737662,0.155380783,NA,10047895,Weight decreased,10022891,Investigations,Inv,bosentan,DB00559
,18804,DB08931,10047895,314,6263,117,2329,1,0.998000955,0.800076481,1.251577651,1,DB0893110047895_,0,-0.002001046,NA,10047895,Weight decreased,10022891,Investigations,Inv,riociguat,DB08931
,18805,DB00230,10016338,44,19630,11,8640,0.106414611,1.760539368,0.894174455,3.781439778,0.220748799,DB0023010016338_,1.510729878,0.565620221,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,18806,DB00381,10016338,41,29319,17,22870,0.033229299,1.881236199,1.045157266,3.532721111,0.091771711,DB0038110016338_,2.388451184,0.631929113,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,18807,DB00404,10016338,49,19843,11,9851,0.013346796,2.211395035,1.133785263,4.718902738,0.044810387,DB0040410016338_,3.105315309,0.793623554,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,18808,DB01076,10016338,40,25707,18,25565,0.0053427,2.2099044,1.23768097,4.09652661,0.021565243,DB0107610016338_,3.836672392,0.792949257,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,18809,DB00230,10035664,505,19169,262,8389,0.028822645,0.843551282,0.723497682,0.985278543,0.082094644,DB0023010035664_,2.499882504,-0.170134582,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pregabalin,DB00230
,18810,DB00381,10035664,1060,28300,860,22027,0.385922663,0.95932748,0.874463544,1.05267673,0.556050682,DB0038110035664_,0.586895834,-0.041522782,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,amlodipine,DB00381
,18811,DB00404,10035664,539,19353,255,9607,0.5412425,1.049272774,0.900472489,1.225182741,0.696612026,DB0040410035664_,0.361526657,0.048097328,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,alprazolam,DB00404
,18812,DB01076,10035664,894,24853,988,24595,0.018855648,0.895467291,0.815675326,0.982940498,0.059002464,DB0107610035664_,2.830176066,-0.110409584,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,18813,DB00230,10042682,75,19599,14,8637,0.001736177,2.360757433,1.322359058,4.526891541,0.008650664,DB0023010042682_,4.750119228,0.858982514,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,18814,DB00381,10042682,154,29206,88,22799,0.019418836,1.36608806,1.043947923,1.79696311,0.06040522,DB0038110042682_,2.806679751,0.311951225,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,18815,DB01076,10042682,116,25631,63,25520,8.99472622453224e-05,1.833263667,1.33691681,2.533863948,0.000729486,DB0107610042682_,7.223170524,0.606097803,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,18820,DB00193,10030124,185,19135,80,8622,0.789928958,1.041969031,0.79633962,1.373768551,0.886130966,DB0019310030124_,0.120890522,0.041112222,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,18822,DB00374,10030124,697,17019,231,5493,0.725804091,0.973859537,0.835298758,1.138620184,0.839398667,DB0037410030124_,0.175069516,-0.026488198,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,18824,DB00524,10030124,123,1454,64,1280,0.000823154,1.691581439,1.228247636,2.347761816,0.004688319,DB0052410030124_,5.362681153,0.525663854,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,18825,DB00557,10030124,56,5931,37,3030,0.227370384,0.773262448,0.500243993,1.207854946,0.382619197,DB0055710030124_,0.960715049,-0.25713677,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,18826,DB01222,10030124,138,9136,51,5354,0.004859511,1.585689844,1.140053136,2.235499974,0.020002892,DB0122210030124_,3.911878427,0.461019545,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,18827,DB01377,10030124,60,3736,50,2620,0.380639522,0.841568529,0.56651594,1.254803754,0.550699573,DB0137710030124_,0.596565859,-0.172487832,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,18828,DB06403,10030124,1005,20466,314,6347,0.920726185,0.992594831,0.870785068,1.133858478,0.964867449,DB0640310030124_,0.035764546,-0.007432724,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,18829,DB08931,10030124,621,5956,198,2248,0.047915945,1.18373671,0.999505627,1.406512831,0.121199181,DB0893110030124_,2.110319964,0.168676139,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,18830,DB09140,10030124,269,3472,88,1710,0.001042137,1.505414086,1.17039664,1.951435169,0.005702033,DB0914010030124_,5.166932545,0.409068001,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,18831,DB09153,10030124,72,7727,46,5653,0.51291088,1.145056579,0.778831634,1.698509794,0.673016298,DB0915310030124_,0.395985733,0.13545405,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,18832,DB11089,10030124,186,9989,136,8271,0.28362138,1.132403086,0.901057654,1.426107599,0.448029566,DB1108910030124_,0.802896053,0.124341999,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,18833,DB00193,10062355,111,19209,56,8646,0.502465402,0.892175004,0.640662435,1.254540568,0.663695668,DB0019310062355_,0.409931565,-0.114092972,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,18835,DB00374,10062355,281,17435,63,5661,0.00780569,1.448175429,1.096501961,1.938104539,0.029199826,DB0037410062355_,3.533592544,0.370304439,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,18836,DB00421,10062355,119,8784,36,5216,0.000295186,1.962774684,1.339489057,2.939382125,0.001991779,DB0042110062355_,6.218727078,0.674359127,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,18839,DB00557,10062355,35,5952,20,3047,0.671241994,0.895890138,0.502089073,1.640760785,0.800526126,DB0055710062355_,0.22248611,-0.109937487,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,18840,DB00695,10062355,313,27736,149,20379,1.01946275223564e-05,1.54345081,1.264756071,1.89041174,0.00011041,DB0069510062355_,9.111307182,0.434020696,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,18841,DB00761,10062355,139,15168,66,8559,0.273286582,1.188370812,0.87923417,1.620175722,0.436252752,DB0076110062355_,0.829533497,0.172583303,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,18843,DB01175,10062355,76,10648,24,4868,0.129744928,1.447708255,0.903205223,2.399337346,0.255303596,DB0117510062355_,1.365301869,0.369981792,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,18844,DB01222,10062355,62,9212,33,5372,0.749128808,1.095625158,0.706013676,1.728205579,0.857708841,DB0122210062355_,0.153490583,0.091325121,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,18845,DB01377,10062355,40,3756,17,2653,0.080390486,1.661841319,0.918666571,3.133397382,0.179058039,DB0137710062355_,1.720045283,0.507926216,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,18846,DB06403,10062355,616,20855,149,6512,0.005057688,1.29089472,1.075268653,1.557834117,0.020648198,DB0640310062355_,3.880127239,0.25533556,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,18847,DB08931,10062355,181,6396,55,2391,0.206980751,1.230191805,0.901484715,1.701753313,0.357600064,DB0893110062355_,1.028340056,0.207170096,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,18848,DB09140,10062355,110,3631,36,1762,0.04833164,1.482658399,1.004457219,2.234589185,0.121937914,DB0914010062355_,2.104243263,0.393836692,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,18849,DB09153,10062355,43,7756,29,5670,0.811262716,1.083978948,0.660455956,1.802767056,0.898552306,DB0915310062355_,0.106970359,0.080638482,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,18850,DB11089,10062355,59,10116,45,8362,0.694306766,1.083801787,0.722043328,1.636499799,0.815971973,DB1108910062355_,0.203375271,0.080475033,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,18851,DB00374,10019194,57,17659,11,5713,0.121423646,1.676318592,0.869355826,3.548063024,0.243477174,DB0037410019194_,1.412732081,0.516600075,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,18853,DB00820,10019194,50,11865,9,5807,0.003252777,2.718887997,1.322512813,6.293171123,0.014443658,DB0082010019194_,4.237499843,1.000222972,female,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,18860,DB00374,10061105,61,17655,13,5711,0.221515689,1.517796483,0.824239521,3.013856341,0.375374455,DB0037410061105_,0.979831204,0.417259601,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,treprostinil,DB00374
,18861,DB00559,10061105,76,9583,21,3285,0.415345188,1.240561314,0.755523244,2.12160974,0.58456566,DB0055910061105_,0.53688617,0.21556395,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,bosentan,DB00559
,18862,DB00820,10061105,63,11852,34,5782,0.664747923,0.903966314,0.585806753,1.416839955,0.795939233,DB0082010061105_,0.228232437,-0.100963183,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,tadalafil,DB00820
,18866,DB00193,10013950,116,19204,43,8659,0.302631788,1.216342873,0.849484243,1.770408361,0.468984261,DB0019310013950_,0.757186071,0.195848711,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,18867,DB01222,10013950,68,9206,37,5368,0.76181072,1.071641868,0.706749847,1.647890275,0.867975499,DB0122210013950_,0.141591791,0.069191928,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,18869,DB01222,10047700,271,9003,109,5296,0.000815915,1.46248941,1.163560542,1.848713116,0.004654654,DB0122210047700_,5.3698876,0.380140059,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,18872,DB00030,10016173,64,2142,43,1778,0.325142903,1.235380903,0.821869057,1.87287631,0.493563155,DB0003010016173_,0.706104455,0.211379346,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin human,DB00030
,18875,DB00959,10008479,153,7925,80,4922,0.221633753,1.187747275,0.898292399,1.580609425,0.375532986,DB0095910008479_,0.979408967,0.172058467,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,18876,DB00959,10013968,400,7678,224,4778,0.221214538,1.111259883,0.937339445,1.319932027,0.375040256,DB0095910013968_,0.98072191,0.105494401,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,18878,DB00959,10038687,50,8028,41,4961,0.194275567,0.753644231,0.487879882,1.16998458,0.342100441,DB0095910038687_,1.072650898,-0.282834864,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,18879,DB00169,10007515,111,38580,102,18073,1.38208076395814e-06,0.50977718,0.385824376,0.674128807,1.91603337978058e-05,DB0016910007515_,10.86266836,-0.67378155,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,18880,DB00531,10007515,40,7212,31,6485,0.553612102,1.160239523,0.706874125,1.920690042,0.707165307,DB0053110007515_,0.346490826,0.148626469,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,cyclophosphamide,DB00531
,18882,DB00169,10007559,253,38438,177,17998,6.09937003001008e-05,0.669279677,0.549678636,0.816334142,0.000523125,DB0016910007559_,7.555689506,-0.401553254,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,18883,DB00531,10007559,61,7191,35,6481,0.039692443,1.57072099,1.018586655,2.456338336,0.105040611,DB0053110007559_,2.253408235,0.451534743,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,cyclophosphamide,DB00531
,18884,DB08889,10007559,34,3131,57,3828,0.167839454,0.72931081,0.461116572,1.137872512,0.30793551,DB0888910007559_,1.177864901,-0.315655287,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,carfilzomib,DB08889
,18885,DB00169,10020772,561,38130,210,17965,0.004510788,1.258606189,1.071056827,1.483521796,0.018808066,DB0016910020772_,3.973469438,0.23000491,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,18886,DB00531,10020772,103,7149,93,6423,1,0.995054685,0.742810526,1.334399809,1,DB0053110020772_,0,-0.004957584,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,cyclophosphamide,DB00531
,18887,DB08889,10020772,50,3115,54,3831,0.551629815,1.138732382,0.756991957,1.710143996,0.705593308,DB0888910020772_,0.348716258,0.129915699,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,carfilzomib,DB08889
,18888,DB00169,10029331,508,38183,292,17883,0.005971183,0.814822864,0.70340883,0.945259399,0.023571757,DB0016910029331_,3.747706021,-0.204784534,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,18889,DB08889,10029331,90,3075,108,3777,0.884948248,1.023580704,0.761837884,1.372565959,0.952079302,DB0888910029331_,0.049106947,0.023306974,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,carfilzomib,DB08889
,18890,DB08889,10030124,27,3138,35,3850,0.898248429,0.946458535,0.549713922,1.613334869,0.956353692,DB0888910030124_,0.044627464,-0.055028118,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,18891,DB00531,10037377,86,7166,70,6446,0.57276427,1.105100567,0.795176106,1.540280514,0.722760866,DB0053110037377_,0.324676863,0.099936341,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclophosphamide,DB00531
,18892,DB08889,10037377,28,3137,41,3844,0.543481794,0.836862537,0.497181192,1.389943439,0.698658234,DB0888910037377_,0.358593592,-0.178095455,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carfilzomib,DB08889
,18913,DB00186,10010264,297,16604,159,9849,0.305359285,1.108009929,0.909268726,1.354184949,0.472153228,DB0018610010264_,0.750451711,0.10256555,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,18915,DB00338,10010264,688,32986,260,22012,1.16533770452993e-15,1.765792504,1.527160629,2.046576371,7.74485500975199e-14,DB0033810010264_,30.18916255,0.5685996,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,18916,DB00455,10010264,145,9256,61,5057,0.0914201,1.298691345,0.954518524,1.785083134,0.197532045,DB0045510010264_,1.621854456,0.2613571,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,18917,DB00582,10010264,40,1090,58,1516,0.917006764,0.959199512,0.619711521,1.471923159,0.963062282,DB0058210010264_,0.037637195,-0.041656184,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,voriconazole,DB00582
,18918,DB01234,10010264,102,31523,104,32784,0.88926281,1.020005471,0.768184231,1.354113045,0.953995558,DB0123410010264_,0.047096264,0.019807991,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,18920,DB11089,10010264,164,10011,90,8317,0.001488293,1.513840451,1.161523321,1.983521435,0.007639964,DB1108910010264_,4.874362413,0.414649767,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,18921,DB00186,10033661,108,16793,87,9921,0.037058747,0.733413002,0.54723822,0.985284172,0.099712269,DB0018610033661_,2.305466548,-0.310046295,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,lorazepam,DB00186
,18924,DB00582,10033661,40,1090,26,1548,0.002226126,2.18427743,1.291766125,3.752389591,0.010614734,DB0058210033661_,4.545512284,0.781285078,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,voriconazole,DB00582
,18926,DB11089,10033661,88,10087,85,8322,0.318824129,0.854149875,0.625762999,1.166391558,0.486914894,DB1108910033661_,0.719665927,-0.157648603,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,docusate,DB11089
,18927,DB00186,10035528,228,16673,146,9862,0.451408716,0.923708695,0.745953193,1.146717357,0.619063371,DB0018610035528_,0.479547636,-0.079358522,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,lorazepam,DB00186
,18929,DB00455,10035528,95,9306,57,5061,0.551512585,0.906413056,0.644717559,1.284210462,0.705529192,DB0045510035528_,0.348807131,-0.098260165,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,loratadine,DB00455
,18931,DB01202,10035528,75,6639,47,5671,0.100860879,1.363041027,0.932409127,2.010335082,0.212126425,DB0120210035528_,1.550572836,0.309718253,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,levetiracetam,DB01202
,18932,DB01234,10035528,547,31078,639,32249,0.04618571,0.88828157,0.79013425,0.998375826,0.117857615,DB0123410035528_,2.138278036,-0.118466503,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,18934,DB11089,10035528,159,10016,122,8285,0.54649953,1.078061781,0.844537904,1.378808009,0.701163672,DB1108910035528_,0.355013935,0.075164781,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,docusate,DB11089
,18945,DB00186,10051398,154,16747,135,9873,0.000927996,0.672546461,0.529511529,0.85495497,0.005178849,DB0018610051398_,5.263172407,-0.396684083,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lorazepam,DB00186
,18949,DB00695,10051398,65,27984,155,20373,3.25271238137054e-17,0.30530712,0.224760387,0.41066693,2.57522725735918e-15,DB0069510051398_,33.59283861,-1.186437059,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,furosemide,DB00695
,18950,DB01202,10051398,38,6676,47,5671,0.100954466,0.686825562,0.435090122,1.077869784,0.212219141,DB0120210051398_,1.550135855,-0.375674932,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levetiracetam,DB01202
,18952,DB00186,10053762,542,16359,368,9640,0.039602905,0.867913311,0.757016465,0.995908224,0.104856445,DB0018610053762_,2.255163057,-0.141663441,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,18953,DB00218,10053762,64,1378,67,883,0.007539628,0.612243048,0.423092316,0.885250295,0.028404632,DB0021810053762_,3.561203045,-0.490625938,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,moxifloxacin,DB00218
,18954,DB01202,10053762,366,6348,346,5372,0.152155098,0.895175834,0.767159106,1.044686822,0.286941939,DB0120210053762_,1.248475386,-0.110735117,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,levetiracetam,DB01202
,18955,DB00186,10054889,33,16868,50,9958,3.05390814564675e-05,0.389642531,0.242996248,0.617348003,0.000288281,DB0018610054889_,8.151573225,-0.942525548,NA,10054889,Transaminases increased,10022891,Investigations,Inv,lorazepam,DB00186
,18957,DB00338,10054889,35,33639,29,22243,0.37371199,0.798043606,0.473730038,1.353899275,0.543504006,DB0033810054889_,0.609718202,-0.225592038,NA,10054889,Transaminases increased,10022891,Investigations,Inv,omeprazole,DB00338
,18960,DB00695,10054889,35,28014,37,20491,0.121811897,0.69193437,0.42301744,1.129715844,0.243995102,DB0069510054889_,1.410607128,-0.368264168,NA,10054889,Transaminases increased,10022891,Investigations,Inv,furosemide,DB00695
,18962,DB01234,10054889,36,31589,77,32811,0.000305488,0.485626085,0.317391847,0.730606922,0.002048148,DB0123410054889_,6.190819496,-0.722316325,NA,10054889,Transaminases increased,10022891,Investigations,Inv,dexamethasone,DB01234
,18985,DB00005,10003553,438,127644,66,42353,7.86614310779268e-11,2.202117651,1.696293351,2.89833956,2.61227506744574e-09,DB0000510003553_,19.76304432,0.789419466,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,18988,DB00295,10011224,126,14537,86,9516,0.778085121,0.959105046,0.72242404,1.278341245,0.879072925,DB0029510011224_,0.128887421,-0.041754673,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,18989,DB00479,10011224,66,549,26,373,0.024941619,1.723797435,1.057007495,2.883750703,0.073348747,DB0047910011224_,2.612529861,0.544529668,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amikacin,DB00479
,18993,DB00904,10011224,524,22545,285,14171,0.052923081,1.155710519,0.99692181,1.341812489,0.130532216,DB0090410011224_,2.036135215,0.144715323,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,18994,DB00987,10011224,29,2075,54,2874,0.218159877,0.743871762,0.455006192,1.193808329,0.371334457,DB0098710011224_,0.990652121,-0.295886622,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cytarabine,DB00987
,18996,DB00295,10016288,73,14590,71,9531,0.0206917,0.671686852,0.477250911,0.945681605,0.063478215,DB0029510016288_,2.757058503,-0.397963042,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,morphine,DB00295
,18999,DB00760,10016288,27,753,36,979,1,0.975110792,0.563888109,1.668128505,1,DB0076010016288_,0,-0.025204181,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,meropenem,DB00760
,19000,DB01263,10016288,47,577,46,819,0.08359623,1.44986864,0.930841115,2.259619814,0.184435985,DB0126310016288_,1.690452842,0.371472959,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,posaconazole,DB01263
,19001,DB00316,10018884,537,64937,387,36566,0.00026157,0.781373553,0.683905773,0.893337256,0.001803612,DB0031610018884_,6.317963812,-0.246701943,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,19008,DB00295,10021097,207,14456,216,9386,1.70566032684785e-06,0.622259918,0.51081038,0.757841597,2.30505304324914e-05,DB0029510021097_,10.67782178,-0.474397399,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,morphine,DB00295
,19011,DB00760,10021097,48,732,54,961,0.472446339,1.166865667,0.764520532,1.776552761,0.638474867,DB0076010021097_,0.448672967,0.154321237,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,meropenem,DB00760
,19012,DB00904,10021097,454,22615,358,14098,0.001164471,0.790573999,0.685635402,0.912057628,0.006247831,DB0090410021097_,5.075520887,-0.234996016,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ondansetron,DB00904
,19013,DB00295,10035528,75,14588,97,9505,9.77894529752595e-06,0.503790829,0.367224629,0.688865727,0.000106501,DB0029510035528_,9.147358464,-0.685594119,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,morphine,DB00295
,19018,DB00904,10035528,380,22689,275,14181,0.06839418,0.863666734,0.736499899,1.013826619,0.158391019,DB0090410035528_,1.842688498,-0.14656831,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,ondansetron,DB00904
,19019,DB00987,10035528,49,2055,91,2837,0.099530339,0.74340843,0.511752293,1.06883382,0.210102227,DB0098710035528_,1.560161072,-0.296509681,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,cytarabine,DB00987
,19022,DB00295,10043071,71,14592,68,9534,0.029291133,0.682225748,0.481714328,0.966802904,0.083139943,DB0029510043071_,2.48723003,-0.382394667,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,morphine,DB00295
,19025,DB00694,10043071,35,599,17,754,0.001538998,2.589854434,1.396497506,4.980775719,0.007857157,DB0069410043071_,4.846330414,0.951601671,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,daunorubicin,DB00694
,19027,DB00987,10043071,75,2029,78,2850,0.067630556,1.350507357,0.965145486,1.8887214,0.157079542,DB0098710043071_,1.851002968,0.300480342,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,cytarabine,DB00987
,19029,DB00295,10047942,107,14556,77,9525,0.545264859,0.909323255,0.671330828,1.2366117,0.700076911,DB0029510047942_,0.356565077,-0.095054632,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,morphine,DB00295
,19030,DB00316,10047942,731,64743,405,36548,0.779847308,1.018904087,0.900538209,1.154092754,0.880132524,DB0031610047942_,0.127682787,0.018727625,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,19035,DB00904,10047942,501,22568,274,14182,0.067707134,1.149060989,0.988158711,1.338285749,0.157215727,DB0090410047942_,1.850136361,0.138945077,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,ondansetron,DB00904
,19036,DB00987,10047942,31,2073,56,2872,0.273143482,0.766975394,0.476145988,1.215164762,0.436117019,DB0098710047942_,0.829844679,-0.26530056,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,cytarabine,DB00987
,19038,DB00295,10048959,136,14527,97,9505,0.544766748,0.917371771,0.700866039,1.20455821,0.699674769,DB0029510048959_,0.357139668,-0.086242468,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,19043,DB00904,10048959,397,22672,172,14284,3.59561040989693e-05,1.454178592,1.211352479,1.751595052,0.000332842,DB0090410048959_,8.00784124,0.3744412,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,19046,DB00295,10051055,57,14606,96,9506,9.25968091703621e-09,0.386443268,0.27317368,0.542448813,2.09819580089911e-07,DB0029510051055_,15.37701782,-0.950770205,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,morphine,DB00295
,19051,DB00904,10051055,221,22848,160,14296,0.168980348,0.864255964,0.701176261,1.067191349,0.309468625,DB0090410051055_,1.172898566,-0.1458863,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,ondansetron,DB00904
,19072,DB05259,10028245,267,11003,65,2663,0.944179966,0.994164141,0.752802652,1.329181225,0.982881997,DB0525910028245_,0.01726621,-0.005852955,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,19083,DB00108,10060891,95,10099,29,3266,0.834393536,1.059385636,0.691114088,1.669224023,0.914096571,DB0010810060891_,0.089819056,0.057689152,NA,10060891,General symptom,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,19085,DB00879,10053762,103,1674,136,3576,0.000394231,1.617731616,1.231583586,2.119846006,0.002532245,DB0087910053762_,5.978648923,0.481024931,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,emtricitabine,DB00879
,19090,DB00005,10047700,1343,126739,238,42181,1.27000314620618e-21,1.878142596,1.634301592,2.165684869,1.56356125049318e-19,DB0000510047700_,43.30215069,0.630283307,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,19096,DB01075,10024774,34,19914,21,11076,0.778442122,0.900506425,0.507523723,1.633580425,0.879226159,DB0107510024774_,0.128713123,-0.104797979,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,19100,DB00542,10016173,52,1634,38,1386,0.520732797,1.160673461,0.744362809,1.824368322,0.679801414,DB0054210016173_,0.385954561,0.149000406,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,benazepril,DB00542
,19102,DB00480,10021015,146,67282,82,67580,1.99470963300408e-05,1.788354944,1.35508936,2.373936226,0.000199357,DB0048010021015_,8.520412385,0.581296172,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,19104,DB00542,10033425,50,1636,27,1397,0.063612196,1.581087871,0.965234292,2.641688083,0.149992965,DB0054210033425_,1.897166887,0.458113136,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,benazepril,DB00542
,19107,DB00480,10034568,80,67348,71,67591,0.464586421,1.130824401,0.811019071,1.579508756,0.631602455,DB0048010034568_,0.45949511,0.122946925,NA,10034568,Peripheral coldness,10047065,Vascular disorders,Vasc,lenalidomide,DB00480
,19112,DB00005,10015090,256,127826,80,42339,0.704736085,1.059898778,0.821340892,1.380449186,0.822904333,DB0000510015090_,0.194915327,0.058173411,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,19113,DB00005,10015967,189,127893,25,42394,2.37336069474768e-06,2.506106047,1.645878563,3.971254969,3.07385000549114e-05,DB0000510015967_,10.38999462,0.918730173,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,etanercept,DB00005
,19114,DB00005,10023874,167,127915,16,42403,4.15632492806559e-08,3.460055369,2.068672232,6.19444915,8.16509721481345e-07,DB0000510023874_,14.01822702,1.241284592,female,10023874,Laryngitis,10021881,Infections and infestations,Infec,etanercept,DB00005
,19116,DB00005,10047531,168,127914,51,42368,0.639083426,1.091084897,0.793079308,1.523845775,0.776154316,DB0000510047531_,0.253403918,0.087172519,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,etanercept,DB00005
,19117,DB00005,10042128,270,127812,30,42389,1.16726259218249e-10,2.984967389,2.04235389,4.511386753,3.76460088779346e-09,DB0000510042128_,19.39762399,1.093588822,female,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,19118,DB00563,10042128,419,46227,121,15227,0.210913181,1.14063226,0.928821567,1.409383481,0.362378858,DB0056310042128_,1.015065044,0.131582722,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,19119,DB00563,10022067,226,46420,72,15276,0.840361936,1.032968429,0.788459288,1.367129225,0.918366576,DB0056310022067_,0.085158648,0.032436628,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,19123,DB00169,10005746,46,38645,29,18146,0.21678417,0.744793215,0.457879571,1.229892752,0.369593539,DB0016910005746_,0.995351422,-0.294648662,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,19125,DB00264,10005746,43,29564,26,24866,0.2263327,1.391023444,0.835273373,2.358872776,0.381282767,DB0026410005746_,0.964214008,0.330039767,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,19126,DB00480,10005746,25,67403,34,67628,0.297532301,0.737752915,0.421898112,1.273665829,0.463431396,DB0048010005746_,0.769096918,-0.304146313,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,lenalidomide,DB00480
,19134,DB00012,10016173,45,1601,32,1281,0.643603977,1.125106731,0.694822706,1.840958375,0.779950693,DB0001210016173_,0.248524575,0.117877903,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,darbepoetin alfa,DB00012
,19137,DB00126,10042772,75,10096,60,5885,0.073225531,0.728666256,0.511133102,1.042564214,0.166889194,DB0012610042772_,1.790425197,-0.316539463,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,19139,DB00169,10042772,233,38458,163,18012,0.000118078,0.669484399,0.545257679,0.823632221,0.000919718,DB0016910042772_,6.991443752,-0.401247416,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,19141,DB00264,10042772,267,29340,296,24596,0.001044563,0.756186754,0.637884833,0.896053222,0.005713524,DB0026410042772_,5.164919348,-0.279466905,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,19142,DB00480,10042772,299,67129,290,67372,0.679928907,1.034775263,0.877134104,1.220826808,0.806422314,DB0048010042772_,0.21514771,0.034184266,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,19146,DB00169,10061394,87,38604,27,18148,0.069740925,1.514778043,0.973415392,2.428252045,0.16082999,DB0016910061394_,1.827407437,0.415268922,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,19148,DB00264,10061394,55,29552,27,24865,0.02589979,1.713938275,1.062475558,2.826969974,0.075474056,DB0026410061394_,2.583966308,0.538793807,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,19149,DB00480,10061394,184,67244,99,67563,3.52120559107461e-07,1.867382808,1.454499324,2.409566923,5.64359079032904e-06,DB0048010061394_,12.08499003,0.624537883,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,19150,DB00005,10029331,308,127774,98,42321,0.773911562,1.04099429,0.826511449,1.320784408,0.876603502,DB0000510029331_,0.131700496,0.040176304,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,19151,DB00563,10061218,185,46461,64,15284,0.713450983,0.950908615,0.711557,1.284965031,0.829983363,DB0056310061218_,0.186349623,-0.050337315,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,19152,DB00005,10050819,135,127947,46,42373,0.863552443,0.971928847,0.690624641,1.389820465,0.937043613,DB0000510050819_,0.065025453,-0.02847268,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,19153,DB00005,10020649,46,128036,9,42410,0.161992743,1.692907832,0.818674978,3.934415273,0.300044182,DB0000510020649_,1.203825541,0.526447661,NA,10020649,Hyperkeratosis,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,19154,DB00005,10061159,342,127740,65,42354,1.5582006952547e-05,1.744455426,1.334453143,2.31149851,0.000160083,DB0000510061159_,8.739816425,0.55644243,NA,10061159,Foot deformity,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,19161,DB00091,10037153,86,5424,36,2634,0.496778457,1.160058678,0.775180951,1.767925981,0.658920207,DB0009110037153_,0.417152834,0.148470588,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,cyclosporine,DB00091
,19166,DB00005,10003399,208,127874,66,42353,0.833828477,1.043837667,0.787604532,1.39894589,0.913682907,DB0000510003399_,0.090271697,0.042903986,NA,10003399,Arthropod bite,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,19167,DB00005,10019303,182,127900,41,42378,0.02446312,1.470777203,1.043051307,2.118085007,0.072318601,DB0000510019303_,2.626673907,0.385790971,NA,10019303,Heart rate increased,10022891,Investigations,Inv,etanercept,DB00005
,19169,DB00005,10061520,454,127628,162,42257,0.427349388,0.927876669,0.773544534,1.117543847,0.595908682,DB0000510061520_,0.517667841,-0.074856455,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,19171,DB00563,10025482,1269,45377,255,15093,2.34055481397877e-14,1.655147228,1.443888134,1.903406242,1.3103617313191e-12,DB0056310025482_,27.36071789,0.503889964,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,19172,DB00563,10037087,485,46161,122,15226,0.00703554,1.311251388,1.072109045,1.614070443,0.026898786,DB0056310037087_,3.615674109,0.270981939,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,19173,DB00563,10046571,588,46058,68,15280,8.61221050506814e-21,2.868814672,2.227247354,3.746515489,9.86370166125125e-19,DB0056310046571_,41.46025525,1.053898938,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,19174,DB00005,10064366,234,127848,112,42307,0.001803548,0.691380801,0.549493797,0.874176092,0.008933622,DB0000510064366_,4.717933393,-0.369064521,NA,10064366,Extra dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,19175,DB00215,10015090,39,11064,16,5260,0.667357648,1.15880588,0.632148027,2.223293821,0.797957321,DB0021510015090_,0.225700166,0.147390061,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,19176,DB00656,10015090,39,11974,24,6595,0.693225371,0.895020621,0.524338615,1.557270568,0.815221746,DB0065610015090_,0.204295121,-0.110908521,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,19177,DB00788,10015090,52,9304,28,5033,1,1.004621376,0.621990378,1.654278514,1,DB0078810015090_,0,0.00461073,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,naproxen,DB00788
,19178,DB06228,10015090,545,15367,614,15462,0.059483281,0.893113086,0.792606235,1.00616029,0.142528682,DB0622810015090_,1.948212025,-0.11304207,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,19181,DB06228,10018836,157,15755,177,15899,0.322497044,0.895116314,0.716541953,1.117309706,0.490827411,DB0622810018836_,0.711662718,-0.11080161,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,19182,DB00921,10003051,184,5661,53,4850,8.64218888436664e-14,2.973884717,2.174438938,4.127866074,4.47605782907541e-12,DB0092110003051_,26.13227841,1.089869084,female,10003051,Application site pain,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,19183,DB00921,10048941,142,5703,43,4860,3.22043174732857e-10,2.813815782,1.983111466,4.064985828,9.74097220696564e-09,DB0092110048941_,18.44692491,1.034541492,female,10048941,Application site vesicles,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,19184,DB00921,10069889,355,5490,133,4770,1.76945986070472e-17,2.3188368,1.887115302,2.862940064,1.44441777759701e-15,DB0092110069889_,34.17107008,0.841065681,NA,10069889,Product adhesion issue,10077536,Product issues,Prod,buprenorphine,DB00921
,19191,DB00316,10040880,49,65425,22,36931,0.390308971,1.257279755,0.745809188,2.183881926,0.560141482,DB0031610040880_,0.579565881,0.228950463,NA,10040880,Skin irritation,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,19193,DB00921,10013573,122,5723,104,4799,0.946212075,0.983677613,0.748813415,1.294155888,0.984724409,DB0092110013573_,0.015393465,-0.016457065,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,buprenorphine,DB00921
,19211,DB00115,10061818,173,18252,139,10333,0.002492308,0.704642574,0.559625603,0.888530279,0.011630737,DB0011510061818_,4.454103907,-0.350064592,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,19212,DB00231,10061818,34,3262,24,2115,0.787590933,0.918547013,0.527237191,1.623950975,0.884935161,DB0023110061818_,0.122240901,-0.084962191,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,19213,DB00327,10061818,87,6051,84,4178,0.034005055,0.715160462,0.522329981,0.97958997,0.09341306,DB0032710061818_,2.370724111,-0.33524834,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,19214,DB00581,10061818,41,2072,28,2041,0.146234182,1.442246354,0.866832693,2.431654749,0.278726198,DB0058110061818_,1.277525348,0.366201866,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,lactulose,DB00581
,19215,DB00761,10061818,222,15085,121,8504,0.820796667,1.034297947,0.823735691,1.303790116,0.904559154,DB0076110061818_,0.100307576,0.033722885,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,19216,DB00813,10061818,123,10449,104,10064,0.350263057,1.139107492,0.868868601,1.495767303,0.519886185,DB0081310061818_,0.654145366,0.130245054,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,19218,DB06589,10061818,63,1967,117,2536,0.021434907,0.694277684,0.499849354,0.956855434,0.065306888,DB0658910061818_,2.72865776,-0.364883277,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,pazopanib,DB06589
,19219,DB09140,10061818,95,3646,27,1771,0.014224458,1.708928092,1.099737069,2.73740043,0.047172582,DB0914010061818_,3.05394245,0.535866327,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,19220,DB11089,10061818,175,10000,150,8257,0.736336881,0.963303192,0.768563146,1.208639719,0.847745865,DB1108910061818_,0.165174375,-0.037387076,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,19223,DB00921,10065059,102,5743,38,4865,7.4068551735707e-06,2.273615712,1.549044532,3.39986234,8.34143908471747e-05,DB0092110065059_,9.391689711,0.821371389,NA,10065059,Application site burn,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,19224,DB08877,10028813,158,3131,110,3119,0.00492819,1.43077313,1.108695236,1.851778491,0.02024181,DB0887710028813_,3.900005011,0.358214949,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ruxolitinib,DB08877
,19225,DB08877,10047700,82,3207,79,3150,0.936471195,1.019525921,0.736247593,1.412487747,0.97657834,DB0887710047700_,0.023700306,0.019337736,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ruxolitinib,DB08877
,19226,DB05259,10021789,52,11218,16,2712,0.441750314,0.785716339,0.440774425,1.476719398,0.609894929,DB0525910021789_,0.494468584,-0.241159443,NA,10021789,Infection,10021881,Infections and infestations,Infec,glatiramer,DB05259
,19230,DB09053,10035664,108,2177,263,3789,0.004425519,0.714753462,0.562368476,0.903453009,0.018527478,DB0905310035664_,3.988500365,-0.335817605,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ibrutinib,DB09053
,19232,DB09053,10046571,66,2219,39,4013,2.51570081592361e-08,3.059919845,2.021680214,4.686624874,5.16401374045701e-07,DB0905310046571_,14.47638152,1.118388721,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ibrutinib,DB09053
,19235,DB00996,10027091,66,38887,62,22363,0.005799229,0.612213021,0.426071769,0.880590051,0.023043497,DB0099610027091_,3.770371675,-0.490674984,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,19237,DB00281,10002034,171,11287,85,5586,1,0.995633333,0.761588782,1.309796043,1,DB0028110002034_,0,-0.004376228,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,lidocaine,DB00281
,19238,DB00321,10002034,71,7376,32,2818,0.439510704,0.847707972,0.549683913,1.333188141,0.607910896,DB0032110002034_,0.497726961,-0.165219075,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,amitriptyline,DB00321
,19239,DB00341,10002034,127,11278,53,5015,0.745672042,1.065527721,0.76609373,1.500031889,0.85479359,DB0034110002034_,0.156895254,0.063470189,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,cetirizine,DB00341
,19241,DB01409,10002034,96,5935,72,3894,0.426547278,0.874825139,0.635964552,1.207921024,0.595248079,DB0140910002034_,0.51877702,-0.133731254,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,tiotropium,DB01409
,19242,DB00207,10003658,44,9036,66,5389,2.28377664339934e-06,0.397619067,0.26476079,0.592084466,2.97516746943249e-05,DB0020710003658_,10.42262514,-0.92226085,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,azithromycin,DB00207
,19244,DB00281,10003658,70,11388,85,5586,2.49186542736483e-08,0.403975538,0.289649494,0.561885829,5.11908423276941e-07,DB0028110003658_,14.48512009,-0.906400952,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,lidocaine,DB00281
,19246,DB00341,10003658,75,11330,62,5006,0.000374271,0.534473786,0.376029006,0.76209106,0.00242607,DB0034110003658_,6.021482675,-0.626472594,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,cetirizine,DB00341
,19248,DB00480,10003658,558,66870,736,66926,9.81267811434174e-07,0.758791053,0.678147998,0.848672718,1.40674253741736e-05,DB0048010003658_,11.17164869,-0.276028832,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,19250,DB00761,10003658,285,15022,239,8386,6.11573562437132e-06,0.66567473,0.557385612,0.79562507,7.05064847942287e-05,DB0076110003658_,9.559805869,-0.406954122,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,19251,DB00193,10007559,131,19189,82,8620,0.021062582,0.717645629,0.539805968,0.958852472,0.064412907,DB0019310007559_,2.74244124,-0.331779385,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,tramadol,DB00193
,19252,DB00207,10007559,36,9044,32,5423,0.131242395,0.674620164,0.406762975,1.123360622,0.257549275,DB0020710007559_,1.356544217,-0.393605467,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,azithromycin,DB00207
,19253,DB00215,10007559,70,11033,40,5236,0.357667477,0.830533709,0.55448893,1.259203769,0.527362407,DB0021510007559_,0.639867288,-0.185686761,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,citalopram,DB00215
,19255,DB00281,10007559,43,11415,39,5632,0.006645598,0.54398497,0.343977471,0.862772787,0.02570858,DB0028110007559_,3.660930503,-0.608833661,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,lidocaine,DB00281
,19256,DB00321,10007559,40,7407,15,2835,1,1.020663151,0.550633001,1.992197044,1,DB0032110007559_,0,0.020452564,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,amitriptyline,DB00321
,19257,DB00341,10007559,58,11347,27,5041,0.814849029,0.954336131,0.593914068,1.569489599,0.900608932,DB0034110007559_,0.104684153,-0.046739331,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,cetirizine,DB00341
,19260,DB00813,10007559,48,10524,29,10139,0.051894438,1.594578,0.984431739,2.624795317,0.128598595,DB0081310007559_,2.051059394,0.466609124,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,fentanyl,DB00813
,19261,DB00996,10007559,221,38732,198,22227,6.96737492093157e-06,0.640562268,0.525955145,0.780491055,7.91090495882014e-05,DB0099610007559_,9.444683283,-0.445408944,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,gabapentin,DB00996
,19262,DB01234,10007559,178,31447,237,32651,0.013691321,0.779814955,0.638010588,0.951762022,0.045737186,DB0123410007559_,3.084843618,-0.248698625,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,19263,DB01409,10007559,93,5938,79,3887,0.098681306,0.770633735,0.563171334,1.056701993,0.20886871,DB0140910007559_,1.566049406,-0.26054207,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,tiotropium,DB01409
,19264,DB00193,10009033,108,19212,51,8651,0.796683302,0.953560631,0.676687995,1.359222279,0.889943715,DB0019310009033_,0.11659706,-0.047552269,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,19265,DB00207,10009033,71,9009,41,5414,0.922024262,1.040677481,0.697665219,1.57053773,0.965573327,DB0020710009033_,0.035033233,0.039871925,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,19266,DB00215,10009033,65,11038,33,5243,0.745977998,0.935602219,0.605478232,1.470751262,0.855054056,DB0021510009033_,0.156590589,-0.066564872,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,19268,DB00281,10009033,61,11397,23,5648,0.296435103,1.3143557,0.800717539,2.227607604,0.462325136,DB0028110009033_,0.771486877,0.273346584,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,19269,DB00321,10009033,38,7409,14,2836,1,1.038995672,0.549280595,2.079297773,1,DB0032110009033_,0,0.038254547,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amitriptyline,DB00321
,19270,DB00341,10009033,73,11332,31,5037,0.915223581,1.04670253,0.677844608,1.651239794,0.962130801,DB0034110009033_,0.03860487,0.045644775,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,19272,DB00480,10009033,159,67269,188,67474,0.132395394,0.848324009,0.682273432,1.05370578,0.259116656,DB0048010009033_,1.35047691,-0.16449263,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,19274,DB00641,10009033,117,14007,80,12395,0.085282706,1.294173189,0.964543182,1.743847724,0.187210283,DB0064110009033_,1.675522786,0.257872027,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,19275,DB00695,10009033,348,27701,247,20281,0.738405209,1.031519112,0.872873113,1.220425436,0.849356322,DB0069510009033_,0.163276485,0.031032582,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,19276,DB00761,10009033,174,15133,98,8527,1,1.000417671,0.775454418,1.296816929,1,DB0076110009033_,0,0.000417584,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,19277,DB00813,10009033,36,10536,29,10139,0.535006551,1.194592194,0.711604912,2.021472102,0.691531912,DB0081310009033_,0.36884598,0.177804867,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,19278,DB00996,10009033,210,38743,115,22310,0.686357282,1.051547771,0.833218741,1.33259721,0.810800841,DB0099610009033_,0.209732827,0.050263146,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,19287,DB00480,10019663,25,67403,31,67631,0.50435097,0.809182312,0.45804262,1.416209863,0.665390872,DB0048010019663_,0.407380634,-0.211731033,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,lenalidomide,DB00480
,19291,DB00695,10019663,60,27989,70,20458,0.009661114,0.626530645,0.436041513,0.897807414,0.034625358,DB0069510019663_,3.363168965,-0.467557591,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,furosemide,DB00695
,19295,DB01234,10019663,32,31593,35,32853,0.902895245,0.950735126,0.569718204,1.581599384,0.957326661,DB0123410019663_,0.043610607,-0.050519777,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,dexamethasone,DB01234
,19307,DB00641,10040560,19,14105,32,12443,0.024790262,0.523805977,0.280363705,0.953186441,0.073030207,DB0064110040560_,2.616882126,-0.646633937,NA,10040560,Shock,10047065,Vascular disorders,Vasc,simvastatin,DB00641
,19308,DB00695,10040560,51,27998,23,20505,0.059098677,1.623939618,0.974204097,2.785131008,0.141808576,DB0069510040560_,1.953277184,0.48485506,NA,10040560,Shock,10047065,Vascular disorders,Vasc,furosemide,DB00695
,19309,DB00996,10040560,33,38920,17,22408,0.770402175,1.117637135,0.604744985,2.139857053,0.874236414,DB0099610040560_,0.134404443,0.111216756,NA,10040560,Shock,10047065,Vascular disorders,Vasc,gabapentin,DB00996
,19311,DB00193,10042772,94,19226,65,8637,0.009670843,0.649672769,0.468081202,0.906487746,0.034655502,DB0019310042772_,3.362298787,-0.431286476,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,19312,DB00207,10042772,48,9032,20,5435,0.208935556,1.444163404,0.839962287,2.571771943,0.359992861,DB0020710042772_,1.021671078,0.367530195,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,19313,DB00215,10042772,70,11033,41,5235,0.308117188,0.810128255,0.542477135,1.223667439,0.47535497,DB0021510042772_,0.743693449,-0.210562704,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,19315,DB00281,10042772,95,11363,44,5627,0.786162051,1.069184562,0.739184962,1.567730735,0.883958973,DB0028110042772_,0.123344628,0.066896266,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,19316,DB00321,10042772,50,7397,32,2818,0.025390744,0.595291438,0.3736133,0.960934282,0.074355758,DB0032110042772_,2.598894165,-0.518704182,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,19317,DB00341,10042772,84,11321,31,5037,0.417901054,1.205575295,0.788761588,1.886220239,0.586952855,DB0034110042772_,0.532810778,0.186956876,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,19319,DB00588,10042772,143,16381,62,8406,0.299631605,1.183541026,0.871532295,1.623400314,0.465638922,DB0058810042772_,0.76434479,0.168510815,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,19321,DB00695,10042772,374,27675,297,20231,0.306270218,0.920546864,0.787470477,1.076866016,0.473213772,DB0069510042772_,0.748208044,-0.082787369,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,19322,DB00813,10042772,49,10523,36,10132,0.232808388,1.310516383,0.834270105,2.07625316,0.389322336,DB0081310042772_,0.943347651,0.270421245,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,19323,DB01409,10042772,51,5980,37,3929,0.662523216,0.905637287,0.580358541,1.425349488,0.794254303,DB0140910042772_,0.230351588,-0.099116399,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,tiotropium,DB01409
,19324,DB00193,10051055,132,19188,69,8633,0.320360413,0.86072594,0.637771244,1.170379612,0.488537316,DB0019310051055_,0.716339421,-0.149979129,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,tramadol,DB00193
,19325,DB00207,10051055,52,9028,39,5416,0.328361981,0.799905647,0.517239637,1.246187512,0.496945395,DB0020710051055_,0.699275129,-0.223261499,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,azithromycin,DB00207
,19326,DB00215,10051055,56,11047,30,5246,0.643629201,0.8864552,0.558442208,1.432700955,0.779960887,DB0021510051055_,0.248511505,-0.120524691,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,citalopram,DB00215
,19328,DB00281,10051055,61,11397,38,5633,0.284231247,0.793438453,0.519956318,1.224542769,0.448715681,DB0028110051055_,0.80136582,-0.231379306,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,lidocaine,DB00281
,19329,DB00321,10051055,30,7417,21,2829,0.040189743,0.544946036,0.301210686,1.003198061,0.106064409,DB0032110051055_,2.243708739,-0.607068506,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,amitriptyline,DB00321
,19330,DB00341,10051055,48,11357,27,5041,0.318423935,0.789139117,0.481977878,1.316899302,0.48638849,DB0034110051055_,0.720747612,-0.236812653,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,cetirizine,DB00341
,19332,DB00588,10051055,93,16431,85,8383,0.000126943,0.558203811,0.410941616,0.759106451,0.000978181,DB0058810051055_,6.929815673,-0.58303113,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,fluticasone propionate,DB00588
,19333,DB00641,10051055,88,14036,127,12348,0.0003469,0.609599903,0.458602248,0.807293131,0.002277859,DB0064110051055_,6.084519419,-0.494952434,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,simvastatin,DB00641
,19334,DB00695,10051055,196,27853,177,20351,0.045455441,0.809098345,0.656369954,0.997926749,0.116440529,DB0069510051055_,2.150374619,-0.211834805,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,furosemide,DB00695
,19335,DB00761,10051055,166,15141,99,8526,0.652910366,0.944202071,0.730670069,1.225435376,0.787055674,DB0076110051055_,0.239456291,-0.057415077,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,potassium chloride,DB00761
,19336,DB00813,10051055,55,10517,59,10109,0.574189667,0.896044363,0.608442422,1.317760653,0.723968696,DB0081310051055_,0.323007125,-0.109765355,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,fentanyl,DB00813
,19337,DB00996,10051055,213,38740,209,22216,4.8681785000954e-08,0.584474019,0.48026264,0.711289965,9.44354773985295e-07,DB0099610051055_,13.87276392,-0.537042949,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,gabapentin,DB00996
,19338,DB01234,10051055,458,31167,626,32262,7.48678091661942e-06,0.757339381,0.669197351,0.85661497,8.4224282642132e-05,DB0123410051055_,9.382027286,-0.277943802,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,dexamethasone,DB01234
,19339,DB01409,10051055,30,6001,26,3940,0.33800352,0.757599584,0.432314781,1.335790763,0.507096424,DB0140910051055_,0.679054108,-0.277600286,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,tiotropium,DB01409
,19344,DB00281,10058151,42,11416,9,5662,0.017142669,2.314433099,1.109476463,5.411237256,0.054746986,DB0028110058151_,2.905032966,0.839164776,NA,10058151,Pulseless electrical activity,10007541,Cardiac disorders,Card,lidocaine,DB00281
,19354,DB00813,10058151,43,10529,18,10150,0.002866563,2.302662146,1.299463099,4.245299942,0.013030284,DB0081310058151_,4.340479063,0.834065908,NA,10058151,Pulseless electrical activity,10007541,Cardiac disorders,Card,fentanyl,DB00813
,19359,DB00811,10013911,32,2766,30,4126,0.069619776,1.590975806,0.933922802,2.71712098,0.160635166,DB0081110013911_,1.828619534,0.464347542,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,ribavirin,DB00811
,19368,DB00005,10021688,277,127805,49,42370,2.08052271133594e-05,1.874002529,1.378799142,2.594602141,0.000206676,DB0000510021688_,8.484356931,0.628076533,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,etanercept,DB00005
,19369,DB00005,10049848,253,127829,63,42356,0.043363868,1.330637615,1.005912029,1.783116814,0.112391585,DB0000510049848_,2.185766208,0.285658237,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,19370,DB00480,10029331,1752,65676,1826,65836,0.256278261,0.961801279,0.899470346,1.028456259,0.417093842,DB0048010029331_,0.874444041,-0.038947421,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,19371,DB01041,10029331,157,2888,152,2966,0.640630282,1.060810061,0.838141958,1.342881405,0.77754794,DB0104110029331_,0.251609977,0.059032825,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,thalidomide,DB01041
,19372,DB06626,10016256,72,616,159,1293,0.765846828,0.950521174,0.697549586,1.285741889,0.870935515,DB0662610016256_,0.13818734,-0.050744841,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,axitinib,DB06626
,19373,DB00395,10011906,106,2078,60,676,0.001227035,0.574849689,0.409678683,0.81260522,0.006511832,DB0039510011906_,5.034134412,-0.553646684,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,carisoprodol,DB00395
,19375,DB06196,10034829,64,976,9,274,0.055964743,1.995612209,0.971807172,4.620812843,0.136034309,DB0619610034829_,1.994848154,0.690950875,NA,10034829,Pharyngeal oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,icatibant,DB06196
,19376,DB06404,10034829,138,2931,39,861,0.92683786,1.039458239,0.717305333,1.536416351,0.96908919,DB0640410034829_,0.031398628,0.038699653,NA,10034829,Pharyngeal oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human c1-esterase inhibitor,DB06404
,19378,DB06404,10042682,61,3008,7,893,0.012392825,2.586683475,1.176665249,6.726834475,0.042233296,DB0640410042682_,3.164546354,0.950376543,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,human c1-esterase inhibitor,DB06404
,19399,DB00338,10019303,187,33487,74,22198,0.000134334,1.675108752,1.272486187,2.224698003,0.001025324,DB0033810019303_,6.882746821,0.51587809,NA,10019303,Heart rate increased,10022891,Investigations,Inv,omeprazole,DB00338
,19400,DB00451,10019303,287,46984,59,15360,0.000877003,1.590210123,1.197319869,2.143125785,0.004945723,DB0045110019303_,5.309232146,0.46386616,NA,10019303,Heart rate increased,10022891,Investigations,Inv,levothyroxine,DB00451
,19401,DB00476,10019303,79,17178,29,6148,0.912944811,0.974968039,0.629052607,1.549642837,0.961080181,DB0047610019303_,0.039697439,-0.025350589,NA,10019303,Heart rate increased,10022891,Investigations,Inv,duloxetine,DB00476
,19402,DB00656,10019303,59,11954,30,6589,0.824401775,1.084022715,0.686429145,1.744799331,0.906981582,DB0065610019303_,0.097633136,0.080678857,NA,10019303,Heart rate increased,10022891,Investigations,Inv,trazodone,DB00656
,19405,DB01373,10019303,95,22625,27,7354,0.598695806,1.143647788,0.738526061,1.82626062,0.743533137,DB0137310019303_,0.296341945,0.134222968,NA,10019303,Heart rate increased,10022891,Investigations,Inv,calcium,DB01373
,19427,DB00091,10037660,125,5385,98,2572,0.000369576,0.609241205,0.461892389,0.805497074,0.002401262,DB0009110037660_,6.031760882,-0.495541022,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,19429,DB00737,10037660,49,2752,18,914,0.67213122,0.904124218,0.514251779,1.657887681,0.800970013,DB0073710037660_,0.22193177,-0.100788518,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,meclizine,DB00737
,19430,DB06637,10037660,76,6086,43,1976,0.005121226,0.573896729,0.388304754,0.857812895,0.020857053,DB0663710037660_,3.870063118,-0.555305814,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,19432,DB11365,10037660,71,1574,66,1482,1,1.012876859,0.708496274,1.449620742,1,DB1136510037660_,0,0.012794657,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sennosides,DB11365
,19434,DB00169,10041466,112,38579,54,18121,0.867902695,0.974193933,0.697676077,1.374883724,0.94089014,DB0016910041466_,0.060928894,-0.026144885,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,19436,DB00316,10041466,179,65295,67,36886,0.003428701,1.50923931,1.13345137,2.030075294,0.015073322,DB0031610041466_,4.194828847,0.411605756,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,19438,DB00451,10041466,147,47124,47,15372,1,1.02025831,0.729682975,1.449577648,1,DB0045110041466_,0,0.02005584,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,19439,DB00476,10041466,68,17189,15,6162,0.10384604,1.625023087,0.918681353,3.063639499,0.216780619,DB0047610041466_,1.52886941,0.485522023,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,19440,DB00656,10041466,38,11975,16,6603,0.39635196,1.309568275,0.712364865,2.517497782,0.565971004,DB0065610041466_,0.569212431,0.269697522,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,19499,DB00169,10073085,98,38593,44,18131,0.857238835,1.046372093,0.725732821,1.530027878,0.931519401,DB0016910073085_,0.070938262,0.045329032,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,19501,DB00316,10073085,92,65382,24,36929,0.000446929,2.165122343,1.369037766,3.550241174,0.002813103,DB0031610073085_,5.873467056,0.772476869,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,19503,DB00338,10073085,59,33615,30,22242,0.278579961,1.301275689,0.824637981,2.092880111,0.442378751,DB0033810073085_,0.815588861,0.263345082,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,19504,DB00451,10073085,81,47190,38,15381,0.069804016,0.694766603,0.466810572,1.050617451,0.160959148,DB0045110073085_,1.826604686,-0.364179313,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,19515,DB00230,10010144,238,19436,134,8517,0.023322239,0.778288806,0.626172482,0.970674464,0.069636386,DB0023010010144_,2.664468056,-0.250657607,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,19516,DB00316,10010144,4015,61459,1861,35092,3.01094885331838e-13,1.231827224,1.163848306,1.304179878,1.45216129558667e-11,DB0031610010144_,24.95538303,0.208498615,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,19517,DB00327,10010144,195,5943,89,4173,0.000749227,1.538401043,1.187312682,2.006199824,0.004329651,DB0032710010144_,5.442268267,0.430743593,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,hydromorphone,DB00327
,19519,DB00404,10010144,1909,17983,830,9032,0.000889089,1.155202351,1.060033764,1.259635397,0.005002075,DB0040410010144_,5.297902422,0.144275524,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,19522,DB00722,10010144,553,24850,662,25370,0.006338941,0.85283103,0.759349362,0.95754881,0.024748112,DB0072210010144_,3.699006074,-0.15919384,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,19523,DB00736,10010144,61,10530,28,5525,0.654619652,1.143057673,0.718580065,1.859679654,0.78836755,DB0073610010144_,0.237790863,0.133706841,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,esomeprazole,DB00736
,19524,DB00788,10010144,215,9141,185,4876,3.48499390080589e-06,0.619919094,0.505330397,0.761159051,4.30667911061038e-05,DB0078810010144_,10.05275837,-0.478166304,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,naproxen,DB00788
,19525,DB01050,10010144,629,17479,358,9013,0.150930169,0.905989787,0.79243177,1.037056367,0.285204853,DB0105010010144_,1.254547575,-0.098727245,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,19526,DB01069,10010144,239,6461,48,2347,0.000126991,1.80863409,1.316542607,2.529466246,0.000978301,DB0106910010144_,6.929693028,0.592571914,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,promethazine,DB01069
,19532,DB00115,10033295,50,18375,25,10447,0.632610447,1.137103759,0.68980499,1.919362361,0.771304385,DB0011510033295_,0.259672191,0.128484468,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,19533,DB00230,10033295,194,19480,106,8545,0.077465591,0.802854618,0.62946439,1.02857208,0.174055056,DB0023010033295_,1.748383616,-0.21958163,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,19534,DB00327,10033295,126,6012,87,4175,1,1.005746673,0.756973577,1.341342634,1,DB0032710033295_,0,0.005730224,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,hydromorphone,DB00327
,19536,DB00404,10033295,262,19630,222,9640,5.60150402105185e-09,0.579564063,0.482005733,0.697405164,1.3312435189272e-07,DB0040410033295_,15.83198217,-0.545479074,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,19538,DB00588,10033295,65,16459,33,8435,1,1.009440995,0.653614074,1.586052792,1,DB0058810033295_,0,0.009396707,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,19539,DB00722,10033295,82,25321,157,25875,2.65426888888563e-06,0.533729571,0.403302568,0.701886443,3.3974900289437e-05,DB0072210033295_,10.28988853,-0.62786599,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,19540,DB00736,10033295,43,10548,24,5529,0.797763508,0.939151726,0.556597177,1.619804197,0.890715054,DB0073610033295_,0.115730707,-0.06277823,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,esomeprazole,DB00736
,19544,DB11089,10033295,33,10142,37,8370,0.22901887,0.736079652,0.445676501,1.211002981,0.384734648,DB1108910033295_,0.955201407,-0.306416943,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,19559,DB00480,10028997,59,67369,82,67580,0.063455179,0.721770314,0.507466894,1.021144365,0.149710023,DB0048010028997_,1.899055035,-0.326048315,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,19560,DB00421,10013573,437,8466,216,5036,0.0309748,1.203419532,1.016143143,1.428572911,0.086877514,DB0042110013573_,2.443256037,0.185167115,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,19561,DB00421,10020642,75,8828,20,5232,0.000892972,2.222359789,1.340691088,3.848458596,0.005019087,DB0042110020642_,5.29450727,0.798569599,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,spironolactone,DB00421
,19563,DB00421,10033557,173,8730,30,5222,2.15829105224551e-12,3.449179036,2.326841534,5.274830412,9.20205682210433e-11,DB0042110033557_,23.109009,1.238136242,female,10033557,Palpitations,10007541,Cardiac disorders,Card,spironolactone,DB00421
,19565,DB00421,10037377,74,8829,32,5220,0.157682361,1.367198275,0.890306049,2.142736212,0.294366539,DB0042110037377_,1.222929557,0.312763591,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,19568,DB00108,10051792,42,10152,10,3285,0.423976864,1.358996796,0.670055885,3.041377088,0.59277829,DB0010810051792_,0.522934828,0.306746777,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,natalizumab,DB00108
,19569,DB14512,10011224,231,4613,96,2316,0.133344392,1.208017993,0.942896014,1.557503812,0.260456071,DB1451210011224_,1.345321066,0.188980994,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mometasone furoate,DB14512
,19570,DB14512,10047924,77,4767,38,2374,1,1.009118545,0.67338132,1.535073564,1,DB1451210047924_,0,0.009077222,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mometasone furoate,DB14512
,19572,DB00068,10028372,53,2181,22,643,0.209341697,0.710336856,0.420913432,1.236452797,0.360380148,DB0006810028372_,1.020595838,-0.342015977,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1b,DB00068
,19573,DB00068,10033775,40,2194,12,653,1,0.992102242,0.506615495,2.090145405,1,DB0006810033775_,0,-0.007929111,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,interferon beta-1b,DB00068
,19576,DB01062,10005750,35,4451,17,1728,0.440976685,0.799298322,0.434613606,1.525758991,0.609206747,DB0106210005750_,0.495597583,-0.224021034,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,oxybutynin,DB01062
,19577,DB08893,10005750,76,2009,24,1034,0.040763916,1.629599744,1.010998269,2.714058887,0.10716002,DB0889310005750_,2.233432052,0.488334429,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,mirabegron,DB08893
,19585,DB08908,10005750,45,10628,10,3269,0.426666683,1.384081011,0.686694138,3.084001962,0.5953831,DB0890810005750_,0.518550215,0.325036389,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,dimethyl fumarate,DB08908
,19588,DB00476,10014551,40,17217,11,6166,0.525603102,1.302276008,0.655266481,2.815850397,0.683571429,DB0047610014551_,0.380424124,0.264113509,NA,10014551,Emotional disorder,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,19591,DB00476,10027951,417,16840,137,6040,0.406786312,1.091712689,0.895864498,1.337034943,0.576306791,DB0047610027951_,0.551115137,0.087747737,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,19594,DB00476,10042464,219,17038,82,6095,0.742030232,0.955399325,0.736678564,1.249123368,0.85212393,DB0047610042464_,0.160023304,-0.045625884,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,19598,DB01164,10020100,20,6504,31,7905,0.481334444,0.78414664,0.423133556,1.421804279,0.646014749,DB0116410020100_,0.436932944,-0.243159235,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium chloride,DB01164
,19600,DB00669,10012378,118,6259,14,1083,0.214366686,1.458335366,0.831672379,2.759634102,0.366718408,DB0066910012378_,1.003161006,0.377295625,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,sumatriptan,DB00669
,19601,DB05259,10012378,234,11036,64,2664,0.375474835,0.88257431,0.664450061,1.18662962,0.545332971,DB0525910012378_,0.606358714,-0.124912289,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,glatiramer,DB05259
,19602,DB00178,10016256,94,1343,103,1577,0.658139556,1.071592748,0.793651162,1.445565036,0.7911279,DB0017810016256_,0.23429563,0.069146091,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ramipril,DB00178
,19603,DB00669,10016256,273,6104,36,1061,0.139146233,1.318091691,0.922348578,1.933465431,0.268604909,DB0066910016256_,1.314513721,0.276185002,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,19604,DB05259,10016256,678,10592,174,2554,0.475347088,0.939554292,0.789592899,1.122606425,0.640973591,DB0525910016256_,0.444767023,-0.062349673,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,19605,DB00541,10028533,51,3083,61,4236,0.500177685,1.148718188,0.773703247,1.699339175,0.661779581,DB0054110028533_,0.412822738,0.138646701,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,vincristine,DB00541
,19606,DB00563,10028533,32,46614,24,15324,0.002935262,0.438325559,0.250102325,0.777960207,0.013272554,DB0056310028533_,4.322056964,-0.824793359,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,methotrexate,DB00563
,19608,DB01234,10028533,41,31584,57,32831,0.158370551,0.747703076,0.487805245,1.137076987,0.295314952,DB0123410028533_,1.219712858,-0.290749337,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,19615,DB00051,10047924,48,25683,12,11408,0.091690944,1.776715049,0.92926447,3.676076447,0.197978928,DB0005110047924_,1.61959468,0.574766181,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,19616,DB00028,10037377,76,13382,43,5572,0.129581971,0.735932625,0.499114815,1.097568661,0.255068866,DB0002810037377_,1.366221708,-0.306616706,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human immunoglobulin g,DB00028
,19617,DB00682,10037377,256,19203,239,16125,0.256049514,0.899444414,0.750144166,1.078772308,0.41681406,DB0068210037377_,0.875115055,-0.105978024,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,19625,DB08910,10024855,70,16674,55,17433,0.12737669,1.33064538,0.920756333,1.931419123,0.251924369,DB0891010024855_,1.378626359,0.285664073,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,19626,DB08910,10049848,96,16648,109,17379,0.575416396,0.919432533,0.690834588,1.221955188,0.724854787,DB0891010049848_,0.321783938,-0.083998611,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,19627,DB08910,10061225,31,16713,22,17466,0.171394496,1.472551688,0.825203935,2.670312359,0.312756731,DB0891010061225_,1.162329609,0.386996738,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,pomalidomide,DB08910
,19628,DB00367,10019211,281,22519,7,460,0.525276017,0.820015001,0.389651347,2.070038401,0.683356683,DB0036710019211_,0.380738326,-0.198432644,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,levonorgestrel,DB00367
,19630,DB01097,10039073,404,5861,76,1427,0.048796732,1.294207199,1.003230586,1.687781853,0.122785955,DB0109710039073_,2.097312641,0.257898306,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,19631,DB01611,10039073,573,11340,91,2270,0.047620952,1.26042963,1.003772844,1.59765922,0.120618331,DB0161110039073_,2.115124009,0.231452639,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,19632,DB05259,10024855,90,11180,24,2704,0.636331819,0.906965917,0.571567558,1.491318248,0.773934265,DB0525910024855_,0.256268337,-0.097650408,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,19633,DB00381,10021789,236,29124,147,22740,0.033984233,1.253521944,1.01513808,1.552052919,0.0933705,DB0038110021789_,2.371179826,0.225957144,NA,10021789,Infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,19634,DB00381,10033645,80,29280,94,22793,0.007284621,0.662525338,0.485217389,0.902758414,0.02762009,DB0038110033645_,3.589211882,-0.411696475,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,19637,DB01590,10020772,88,4650,79,2788,0.012095621,0.667936719,0.485423415,0.920283561,0.041394882,DB0159010020772_,3.184598017,-0.403561842,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,everolimus,DB01590
,19641,DB00335,10022437,167,8299,86,5379,0.091117304,1.258586708,0.96227545,1.65611554,0.197047871,DB0033510022437_,1.62430858,0.229989431,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,atenolol,DB00335
,19642,DB01261,10022437,54,3727,55,3248,0.439819924,0.85565372,0.574942667,1.272901396,0.608136413,DB0126110022437_,0.497356058,-0.155889518,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,sitagliptin,DB01261
,19643,DB00335,10043882,35,8431,17,5448,0.394000143,1.330357509,0.724779076,2.535104797,0.563945424,DB0033510043882_,0.572797798,0.28544771,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,atenolol,DB00335
,19645,DB00264,10006093,247,29360,349,24543,2.6694451647105e-10,0.591634016,0.500175345,0.69899731,8.16837789923346e-09,DB0026410006093_,18.62299549,-0.524867052,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,metoprolol,DB00264
,19648,DB00005,10018286,48,128034,13,42406,0.656612963,1.222917812,0.652082793,2.460641889,0.790020726,DB0000510018286_,0.235696099,0.201239653,NA,10018286,Gingival pain,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,19649,DB00005,10023215,159,127923,65,42354,0.163625252,0.809885281,0.603113276,1.098417445,0.302294132,DB0000510023215_,1.19635479,-0.21086267,NA,10023215,Joint effusion,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,19652,DB06769,10016288,30,637,59,997,0.371567233,0.795942749,0.489314163,1.271316215,0.541223281,DB0676910016288_,0.613923366,-0.228228019,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,bendamustine,DB06769
,19656,DB00073,10047942,91,7315,118,6289,0.004060884,0.663046711,0.49769222,0.880943332,0.017301294,DB0007310047942_,4.056973984,-0.410909837,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,rituximab,DB00073
,19658,DB01015,10033661,119,9768,148,9233,0.030763666,0.760029358,0.59094917,0.975782197,0.086409805,DB0101510033661_,2.448654121,-0.274398218,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,sulfamethoxazole,DB01015
,19660,DB01164,10040047,114,6410,172,7764,0.072056234,0.8028064,0.626454105,1.025665732,0.16488481,DB0116410040047_,1.802508168,-0.219641689,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,calcium chloride,DB01164
,19665,DB01080,10041349,66,1993,64,2048,0.789417464,1.059721265,0.73551989,1.527526006,0.885855574,DB0108010041349_,0.12120135,0.058005916,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,vigabatrin,DB01080
,19667,DB00787,10003549,481,16519,485,16763,0.9220459,1.00640178,0.883642099,1.146189214,0.965576752,DB0078710003549_,0.035029685,0.006381376,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,19668,DB00813,10003549,227,10345,159,10009,0.002015833,1.381276495,1.120703573,1.70575462,0.009787782,DB0081310003549_,4.626620416,0.323008068,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,19669,DB00836,10003549,226,5309,158,3917,0.635474876,1.055343961,0.853648949,1.307136333,0.773469339,DB0083610003549_,0.256869249,0.053866743,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,19670,DB00874,10003549,97,3238,71,1905,0.168920396,0.80381478,0.582499636,1.113666588,0.30939844,DB0087410003549_,1.173125384,-0.218386409,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,19671,DB01432,10003549,44,1247,16,654,0.268470898,1.442008063,0.790447511,2.759939633,0.430942554,DB0143210003549_,0.841780483,0.36603663,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,cholestyramine,DB01432
,19672,DB01591,10003549,53,1902,34,622,0.003585117,0.509900569,0.321972148,0.817138811,0.015618595,DB0159110003549_,4.159293117,-0.673539536,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,solifenacin,DB01591
,19673,DB08910,10003549,443,16301,487,17001,0.444396757,0.948697765,0.830722428,1.083222406,0.612450846,DB0891010003549_,0.490286591,-0.052665008,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,19674,DB00230,10016173,909,18765,256,8395,2.98357946721776e-11,1.588508396,1.377859005,1.836352908,1.05870521749784e-09,DB0023010016173_,20.66621917,0.46279546,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,19675,DB00787,10016173,423,16577,334,16914,0.000543612,1.292199778,1.11501286,1.498528443,0.003307219,DB0078710016173_,5.711647599,0.25634602,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,19676,DB00836,10016173,182,5353,104,3971,0.03879042,1.298161694,1.010921072,1.674175691,0.103235577,DB0083610016173_,2.270741743,0.260949182,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,loperamide,DB00836
,19677,DB00874,10016173,114,3221,53,1923,0.143747093,1.2840769,0.914290197,1.823304958,0.275151936,DB0087410016173_,1.290431841,0.250040094,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,guaifenesin,DB00874
,19678,DB01432,10016173,36,1255,15,655,0.550532056,1.25249448,0.663036291,2.481172424,0.704654224,DB0143210016173_,0.350048059,0.225137147,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,cholestyramine,DB01432
,19679,DB01591,10016173,110,1845,32,624,0.550452465,1.162531752,0.768861351,1.800745975,0.704653145,DB0159110016173_,0.35004959,0.150600172,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,solifenacin,DB01591
,19680,DB00215,10016256,711,10392,250,5026,1.90708495929234e-05,1.375450286,1.184336831,1.601340479,0.000191547,DB0021510016256_,8.560379777,0.318781158,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,19681,DB00230,10016256,1047,18627,386,8265,0.002202994,1.203507872,1.066756149,1.359909277,0.010524481,DB0023010016256_,4.554051248,0.185240519,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,19682,DB00874,10016256,217,3118,131,1845,0.863507532,0.980181049,0.779238571,1.236617925,0.937043613,DB0087410016256_,0.065025453,-0.02001798,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,19683,DB01432,10016256,79,1212,47,623,0.438964194,0.864074503,0.586471892,1.284662106,0.607352223,DB0143210016256_,0.498646388,-0.146096284,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cholestyramine,DB01432
,19684,DB01591,10016256,125,1830,46,610,0.584636555,0.905839191,0.632531899,1.315897948,0.732362953,DB0159110016256_,0.31147905,-0.098893482,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,solifenacin,DB01591
,19685,DB06674,10003239,153,4353,40,1450,0.203853409,1.274058565,0.889372695,1.862343303,0.353623946,DB0667410003239_,1.039521229,0.242207526,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,golimumab,DB06674
,19687,DB06674,10003988,56,4450,22,1468,0.509738704,0.839710566,0.502553304,1.449639236,0.670292753,DB0667410003988_,0.400040718,-0.174698011,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,golimumab,DB06674
,19690,DB06674,10052904,47,4459,12,1478,0.544484183,1.298169612,0.675787611,2.696064225,0.699482747,DB0667410052904_,0.35741415,0.260955281,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,golimumab,DB06674
,19697,DB01075,10020642,135,19813,107,10990,0.006962362,0.699874704,0.538370468,0.911603463,0.026684157,DB0107510020642_,3.623685253,-0.356853954,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,19700,DB01075,10043521,149,19799,40,11057,1.73474152764038e-05,2.080227348,1.457428906,3.030405435,0.000176155,DB0107510043521_,8.644147161,0.732477189,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,19701,DB00181,10046735,78,9778,22,5849,0.001222453,2.120724655,1.305570763,3.579965691,0.006492658,DB0018110046735_,5.037083257,0.751757849,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,baclofen,DB00181
,19702,DB01068,10046735,113,13650,28,6812,0.000598697,2.01395322,1.320297124,3.168148331,0.00358959,DB0106810046735_,5.629717214,0.700099567,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,clonazepam,DB01068
,19703,DB01075,10046735,536,19412,271,10826,0.205754437,1.103054907,0.949470643,1.283785272,0.356150196,DB0107510046735_,1.032402739,0.098083519,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,19711,DB01068,10058920,47,13716,18,6822,0.428661935,1.298731895,0.739484638,2.37785139,0.597212069,DB0106810058920_,0.515483005,0.261388323,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,19712,DB01075,10058920,56,19892,12,11085,0.00140078,2.600466362,1.377076713,5.332100346,0.007261513,DB0107510058920_,4.92516709,0.955690799,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,19715,DB01075,10060795,48,19900,18,11079,0.159432908,1.484605098,0.847386282,2.713263803,0.296696802,DB0107510060795_,1.215044529,0.39514881,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,diphenhydramine,DB01075
,19716,DB00853,10011906,190,1631,262,2004,0.269700419,0.891070631,0.726903095,1.090868255,0.432260702,DB0085310011906_,0.838726396,-0.115331583,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,temozolomide,DB00853
,19723,DB00451,10002544,80,47191,16,15403,0.075336564,1.6319198,0.945743705,2.99254048,0.170392942,DB0045110002544_,1.769648086,0.489757113,NA,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,19725,DB00695,10002544,60,27989,8,20520,8.60214789833769e-08,5.498428182,2.617902955,13.31747293,1.5800660902013e-06,DB0069510002544_,13.35804388,1.704462266,female,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,19726,DB00722,10002544,42,25361,15,26017,0.000271066,2.872471876,1.560169273,5.576744184,0.001856913,DB0072210002544_,6.288839733,1.05517294,female,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,19732,DB00046,10003658,56,5403,63,4629,0.140298312,0.761577233,0.520525057,1.111815129,0.270273087,DB0004610003658_,1.308322399,-0.27236369,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,insulin lispro,DB00046
,19733,DB00047,10003658,73,9212,101,8417,0.007490925,0.660417371,0.481148545,0.902731438,0.028267743,DB0004710003658_,3.566033957,-0.414883263,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,insulin glargine,DB00047
,19734,DB00451,10003658,473,46798,226,15193,3.35600628057286e-06,0.679472766,0.578008073,0.800599774,4.17179593685778e-05,DB0045110003658_,10.08457884,-0.386438126,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,19736,DB00722,10003658,250,25153,292,25740,0.130735773,0.876147628,0.736358489,1.041890911,0.256798719,DB0072210003658_,1.359462694,-0.132220677,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,lisinopril,DB00722
,19737,DB01136,10003658,124,9760,187,10928,0.011687268,0.742468457,0.585859137,0.93829497,0.040316005,DB0113610003658_,3.211006736,-0.297774892,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,carvedilol,DB01136
,19739,DB09270,10003658,42,3072,30,2338,0.812042764,1.065496642,0.649016112,1.768835434,0.899039406,DB0927010003658_,0.106428412,0.063441021,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ubidecarenone,DB09270
,19743,DB01136,10005724,52,9832,29,11086,0.002411962,2.021715443,1.258760995,3.305479869,0.011334301,DB0113610005724_,4.479921641,0.70394638,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,carvedilol,DB01136
,19745,DB06643,10005724,45,52376,8,7507,0.53396959,0.806229311,0.375925031,1.981066085,0.690582103,DB0664310005724_,0.370220409,-0.215387072,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,denosumab,DB06643
,19749,DB00047,10013946,42,9243,26,8492,0.115581464,1.48409599,0.888090609,2.523877894,0.234562365,DB0004710013946_,1.450033776,0.394805826,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,19751,DB00695,10013946,198,27851,104,20424,0.005961126,1.396138574,1.094845731,1.78887636,0.023544661,DB0069510013946_,3.748856189,0.333710264,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,19752,DB00722,10013946,162,25241,102,25930,9.61692537741443e-05,1.631562593,1.264890393,2.11270977,0.000770556,DB0072210013946_,7.168398274,0.489538202,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,19753,DB01136,10013946,65,9819,47,11068,0.022455625,1.558849105,1.053594421,2.321667951,0.067622856,DB0113610013946_,2.693809244,0.443947796,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,19755,DB06643,10013946,127,52294,19,7496,0.803119251,0.958129647,0.588520715,1.644913168,0.893441443,DB0664310013946_,0.112674484,-0.042772179,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,19756,DB09270,10013946,32,3082,19,2349,0.47801528,1.283592136,0.703739267,2.4032647,0.643317374,DB0927010013946_,0.441117093,0.249662504,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,ubidecarenone,DB09270
,19757,DB14726,10013946,19,1998,38,2810,0.226059399,0.703252884,0.381748953,1.254820496,0.380956647,DB1472610013946_,0.965069698,-0.352038731,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,dabigatran,DB14726
,19758,DB00046,10015150,34,5425,16,4676,0.046714467,1.831503225,0.982249337,3.557911271,0.118918191,DB0004610015150_,2.129319497,0.605137064,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,insulin lispro,DB00046
,19759,DB00047,10015150,59,9226,34,8484,0.029162957,1.59568591,1.027990337,2.512811998,0.082864497,DB0004710015150_,2.490548577,0.467303681,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,insulin glargine,DB00047
,19760,DB00451,10015150,417,46854,93,15326,0.000642259,1.466638442,1.16795629,1.858142758,0.003813796,DB0045110015150_,5.569130334,0.382973008,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,19761,DB00484,10015150,61,2446,30,1750,0.1066744,1.454632145,0.920536676,2.343609894,0.221148608,DB0048410015150_,1.508920369,0.374753047,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,brimonidine,DB00484
,19762,DB00695,10015150,252,27797,124,20404,0.000236663,1.491736974,1.197478141,1.866302024,0.001657745,DB0069510015150_,6.402297225,0.399941195,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,19763,DB00722,10015150,183,25220,152,25880,0.055167886,1.235446614,0.990159855,1.543303548,0.134635149,DB0072210015150_,2.005186758,0.211432535,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,19764,DB01136,10015150,68,9816,46,11069,0.0081965,1.666901425,1.12877448,2.481422868,0.030395739,DB0113610015150_,3.493452829,0.510966469,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,carvedilol,DB01136
,19766,DB09270,10015150,44,3070,22,2346,0.106122821,1.528222685,0.893624322,2.685181507,0.220395714,DB0927010015150_,1.51233065,0.424105416,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,ubidecarenone,DB09270
,19768,DB00046,10016173,156,5303,129,4563,0.763406851,1.040556161,0.815869328,1.328911899,0.869021853,DB0004610016173_,0.140387007,0.039755341,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin lispro,DB00046
,19769,DB00047,10016173,250,9035,220,8298,0.673736897,1.043677389,0.865009696,1.259874224,0.802138219,DB0004710016173_,0.220474343,0.042750427,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,19770,DB00484,10016173,57,2450,37,1743,0.751060683,1.095985135,0.708544042,1.713513786,0.859340533,DB0048410016173_,0.151590006,0.091653625,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,brimonidine,DB00484
,19772,DB06643,10016173,810,51611,125,7390,0.426117729,0.927829689,0.766399498,1.131149024,0.594791024,DB0664310016173_,0.519545155,-0.074907088,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,19773,DB09270,10016173,116,2998,77,2291,0.374919642,1.151181828,0.850970179,1.56459137,0.544732894,DB0927010016173_,0.607459707,0.140789091,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ubidecarenone,DB09270
,19788,DB00695,10018870,30,28019,44,20484,0.00311603,0.498460725,0.302485936,0.811272841,0.013960262,DB0069510018870_,4.271540397,-0.696230478,NA,10018870,Blood urine present,10022891,Investigations,Inv,furosemide,DB00695
,19789,DB00722,10018870,29,25374,44,25988,0.102257482,0.675047778,0.40715901,1.103735859,0.214349688,DB0072210018870_,1.540146543,-0.392971809,NA,10018870,Blood urine present,10022891,Investigations,Inv,lisinopril,DB00722
,19795,DB00451,10027141,46,47225,19,15400,0.388229227,0.789504789,0.453397917,1.427312878,0.558223529,DB0045110027141_,0.582995807,-0.236349379,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,19797,DB00722,10027141,33,25370,32,26000,0.901372557,1.056880743,0.629700283,1.775810672,0.956927891,DB0072210027141_,0.044027239,0.055321875,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,19802,DB00046,10028813,262,5197,151,4541,5.38735169343762e-05,1.51601742,1.231095511,1.872245572,0.000470297,DB0004610028813_,7.662145353,0.416086778,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,insulin lispro,DB00046
,19803,DB00047,10028813,541,8744,298,8220,1.80571165216567e-13,1.706583019,1.473927098,1.978837272,8.97223644180997e-12,DB0004710028813_,25.43688615,0.534493137,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,19804,DB00484,10028813,64,2443,32,1748,0.115851184,1.430910611,0.917612385,2.271430908,0.234947023,DB0048410028813_,1.448395222,0.358311033,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,brimonidine,DB00484
,19806,DB09270,10028813,208,2906,101,2267,0.000116541,1.606425677,1.252181092,2.07164603,0.000909762,DB0927010028813_,7.002327396,0.474011635,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ubidecarenone,DB09270
,19807,DB00046,10033775,39,5420,20,4672,0.066329072,1.680797566,0.95521005,3.046257491,0.154767835,DB0004610033775_,1.865829122,0.519268423,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,insulin lispro,DB00046
,19808,DB00047,10033775,52,9233,29,8489,0.033784537,1.648562289,1.026269311,2.696010087,0.092945584,DB0004710033775_,2.375741071,0.499903568,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,19811,DB09270,10033775,50,3064,12,2356,8.84075464670914e-05,3.203218177,1.677328666,6.625336823,0.00071848,DB0927010033775_,7.238372222,1.164155985,female,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,ubidecarenone,DB09270
,19813,DB00046,10037087,72,5387,30,4662,0.00062864,2.076806724,1.33634651,3.300447268,0.003745619,DB0004610037087_,5.587168479,0.730831485,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,insulin lispro,DB00046
,19814,DB00451,10037087,1161,46110,212,15207,7.33395856012885e-17,1.806188022,1.556916944,2.103245064,5.53945691818928e-15,DB0045110037087_,32.82687993,0.591218559,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,19815,DB00484,10037087,53,2454,34,1746,0.661978159,1.109092645,0.704278202,1.767746984,0.793904753,DB0048410037087_,0.230791783,0.103542245,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,brimonidine,DB00484
,19816,DB00695,10037087,533,27516,244,20284,4.17197022555767e-10,1.610278316,1.379711922,1.883510136,1.23979917895741e-08,DB0069510037087_,18.20573133,0.476407031,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,19817,DB00722,10037087,507,24896,313,25719,6.83482033076056e-13,1.673326094,1.448948208,1.934854318,3.12984760268365e-11,DB0072210037087_,24.18745171,0.514813319,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,19818,DB01136,10037087,186,9698,138,10977,0.000204548,1.525535917,1.215298035,1.91874081,0.001468197,DB0113610037087_,6.523720292,0.422345769,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,carvedilol,DB01136
,19820,DB09270,10037087,110,3004,33,2335,4.9897251476245e-07,2.590526403,1.734215979,3.962928628,7.73547186701917e-06,DB0927010037087_,11.76969407,0.951861099,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ubidecarenone,DB09270
,19823,DB00047,10038063,31,9254,27,8491,0.895676378,1.053495063,0.607890732,1.836145459,0.95615204,DB0004710038063_,0.044838341,0.052113268,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,19824,DB00451,10038063,152,47119,60,15359,0.230476225,0.825752875,0.608298779,1.133452608,0.386491918,DB0045110038063_,0.950644323,-0.191459733,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,19826,DB00695,10038063,130,27919,111,20417,0.239658198,0.856476062,0.659268333,1.114307106,0.397489634,DB0069510038063_,0.922586422,-0.15492891,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,19827,DB01136,10038063,47,9837,60,11055,0.560604754,0.880331133,0.587253218,1.312786428,0.713227651,DB0113610038063_,0.337954623,-0.127457155,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,19830,DB14726,10038063,71,1946,88,2760,0.413998303,1.144270286,0.82038021,1.591428709,0.583267307,DB1472610038063_,0.539109696,0.134767129,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,dabigatran,DB14726
,19834,DB00695,10042209,91,27958,28,20500,2.39447662337823e-05,2.38297375,1.544591869,3.783333412,0.000232676,DB0069510042209_,8.365864265,0.868349183,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,19835,DB00722,10042209,108,25295,49,25983,1.20621253223731e-06,2.264005117,1.600312026,3.243045901,1.69226356889738e-05,DB0072210042209_,10.98685844,0.81713542,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,19852,DB00046,10047700,165,5294,102,4590,0.008874307,1.402481755,1.085422763,1.819339798,0.032356937,DB0004610047700_,3.430926854,0.338243349,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,insulin lispro,DB00046
,19853,DB00047,10047700,309,8976,184,8334,1.8742397817407e-06,1.559188743,1.291598995,1.886421052,2.50073059203321e-05,DB0004710047700_,10.59634254,0.44416565,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,19855,DB06643,10047700,258,52163,68,7447,2.32823959784087e-05,0.541677558,0.412697803,0.719238942,0.000227333,DB0664310047700_,8.389096625,-0.613084367,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,19856,DB09270,10047700,75,3039,40,2328,0.070744579,1.43623369,0.961885942,2.172692115,0.162602419,DB0927010047700_,1.816447207,0.362024194,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ubidecarenone,DB09270
,19868,DB00563,10039073,1569,45077,369,14979,1.41368423708371e-09,1.412899467,1.25864372,1.589344082,3.8014005290788e-08,DB0056310039073_,17.08531118,0.345643953,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,19869,DB00005,10007739,310,127772,55,42364,6.51183407214341e-06,1.868685457,1.39880045,2.53758959,7.45056309081681e-05,DB0000510007739_,9.504635853,0.62523522,NA,10007739,Cataract,10015919,Eye disorders,Eye,etanercept,DB00005
,19877,DB00381,10040742,43,29317,22,22865,0.132738367,1.524380308,0.891659617,2.676503297,0.259648593,DB0038110040742_,1.348426128,0.421587972,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,19879,DB00695,10040742,57,27992,23,20505,0.016856944,1.815372593,1.100471503,3.088825483,0.054044613,DB0069510040742_,2.917945403,0.596290732,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,19881,DB08910,10070863,116,16628,105,17383,0.311321734,1.154918006,0.878428185,1.519864244,0.478809384,DB0891010070863_,0.736452707,0.144029351,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,pomalidomide,DB08910
,19882,DB00563,10016173,514,46132,128,15220,0.004329539,1.324824701,1.088606275,1.622216392,0.018218512,DB0056310016173_,4.00531705,0.28128015,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,19883,DB00005,10019196,105,127977,30,42389,0.550137653,1.159279,0.766150669,1.802757326,0.704490316,DB0000510019196_,0.350280694,0.14779826,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,19885,DB00563,10040753,730,45916,145,15203,4.64243469660003e-09,1.666855243,1.391636378,2.008036448,1.12331773320021e-07,DB0056310040753_,16.00180908,0.510938763,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,methotrexate,DB00563
,19886,DB00563,10042682,92,46554,19,15329,0.061884299,1.594316278,0.965016985,2.76873936,0.146926997,DB0056310042682_,1.917819432,0.466444978,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,19887,DB00005,10021097,130,127952,51,42368,0.302603513,0.844012517,0.606004726,1.191242439,0.468954267,DB0000510021097_,0.757250026,-0.169587954,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,etanercept,DB00005
,19888,DB00005,10017412,71,128011,23,42396,1,1.022377404,0.630962724,1.715225317,1,DB0000510017412_,0,0.022130703,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,etanercept,DB00005
,19891,DB00207,10072268,62,9018,21,5434,0.022599162,1.778957424,1.067997885,3.076678955,0.067961669,DB0020710072268_,2.688811417,0.576027476,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,azithromycin,DB00207
,19892,DB01060,10072268,49,8538,52,5029,0.003638776,0.555082379,0.367300062,0.837623354,0.015806515,DB0106010072268_,4.147333092,-0.588638745,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,amoxicillin,DB01060
,19893,DB05676,10027599,701,46428,131,25198,2.09840221095112e-35,2.904198485,2.40511251,3.529808087,6.60556911555091e-33,DB0567610027599_,74.09739497,1.066157443,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,19896,DB01024,10013709,74,2137,89,2031,0.150795012,0.790263813,0.56898812,1.094875589,0.285051916,DB0102410013709_,1.255083953,-0.235388449,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,mycophenolic acid,DB01024
,19899,DB00635,10040882,88,32965,64,23730,1,0.989798275,0.708873656,1.388585662,1,DB0063510040882_,0,-0.010254119,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,19911,DB00635,10041834,20,33033,34,23760,0.002151798,0.423109947,0.230717286,0.756635514,0.01033154,DB0063510041834_,4.572553879,-0.860123212,NA,10041834,Squamous cell carcinoma of skin,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,19923,DB00864,10061818,23,6846,44,8348,0.085278222,0.637432312,0.367014559,1.079950248,0.187208256,DB0086410061818_,1.675533613,-0.450307185,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,19940,DB00734,10037660,41,4009,53,4849,0.835111421,0.935663087,0.605464808,1.43688593,0.914659099,DB0073410037660_,0.089203853,-0.066499817,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,19941,DB01156,10037660,164,13458,95,6233,0.092753224,0.799567017,0.616063493,1.042510065,0.199633738,DB0115610037660_,1.611270899,-0.223684926,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,19942,DB01238,10037660,44,5206,36,3466,0.361557394,0.813745575,0.510770529,1.304088269,0.531398798,DB0123810037660_,0.632242507,-0.206107523,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,19952,DB00316,10028334,887,64587,424,36529,0.004550667,1.18321029,1.05191321,1.332441089,0.018942797,DB0031610028334_,3.96633155,0.16823133,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,19953,DB01075,10028334,241,19707,89,11008,0.000785675,1.512548836,1.179963143,1.95348935,0.004506592,DB0107510028334_,5.402214041,0.413796198,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,19954,DB00028,10028813,776,12682,169,5446,8.30976046064022e-17,1.971747823,1.662196462,2.349816184,6.22285053298941e-15,DB0002810028813_,32.71054831,0.678920369,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,human immunoglobulin g,DB00028
,19955,DB00028,10037844,452,13006,315,5300,2.67924099435156e-12,0.584768961,0.503438366,0.679858556,1.12408379148493e-10,DB0002810037844_,22.90888263,-0.536538448,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,human immunoglobulin g,DB00028
,19960,DB00108,10051290,74,10120,26,3269,0.726152093,0.919371919,0.579855726,1.500615477,0.839667763,DB0010810051290_,0.174748985,-0.084064539,NA,10051290,Central nervous system lesion,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,19961,DB05259,10051290,74,11196,30,2698,0.02434213,0.594441424,0.383209425,0.94339052,0.072049196,DB0525910051290_,2.630406119,-0.520133098,NA,10051290,Central nervous system lesion,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,19963,DB01068,10013709,874,12889,436,6404,0.951662774,0.995994419,0.883323249,1.124294982,0.989809117,DB0106810013709_,0.010243166,-0.004013624,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,19964,DB06218,10013709,168,1526,157,1279,0.37785439,0.8968942,0.707946731,1.136667056,0.547800813,DB0621810013709_,0.601843538,-0.108817372,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lacosamide,DB06218
,19966,DB00811,10001551,19,2779,37,4119,0.411895055,0.761152821,0.412564904,1.361219922,0.581328475,DB0081110001551_,0.54243932,-0.272921125,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,ribavirin,DB00811
,19974,DB00008,10016256,179,1346,165,1511,0.086714342,1.217755845,0.967382979,1.533639528,0.189577183,DB0000810016256_,1.662959039,0.197009693,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,peginterferon alfa-2a,DB00008
,19981,DB08934,10037844,137,4352,145,6059,0.023714843,1.315370998,1.030276351,1.678702913,0.070573975,DB0893410037844_,2.651093822,0.274118753,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sofosbuvir,DB08934
,19982,DB00177,10038695,32,4768,30,2820,0.085573504,0.630939176,0.370366112,1.077327539,0.187684055,DB0017710038695_,1.672995288,-0.460545814,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,valsartan,DB00177
,19983,DB06403,10038695,288,21183,116,6545,0.018326998,0.767116161,0.615106752,0.961798841,0.057664009,DB0640310038695_,2.853122058,-0.265117041,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,19985,DB00215,10008531,80,11023,24,5252,0.045766238,1.588153321,0.99433696,2.624695462,0.117025688,DB0021510008531_,2.145361811,0.462571908,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,19986,DB00381,10008531,222,29138,130,22757,0.009604612,1.33371202,1.068574471,1.670271394,0.034475388,DB0038110008531_,3.367509606,0.287966047,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,19987,DB08934,10008531,37,4452,29,6175,0.023886757,1.769505157,1.057232541,2.988337859,0.070969074,DB0893410008531_,2.645511077,0.570699935,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,19989,DB00215,10012378,319,10784,102,5174,0.000318306,1.500469054,1.193812254,1.899031686,0.002117857,DB0021510012378_,6.157350662,0.405777762,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,19991,DB00215,10013573,344,10759,140,5136,0.125789286,1.172934664,0.958105146,1.44211155,0.249754231,DB0021510013573_,1.38727792,0.159508868,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,19992,DB08934,10013573,132,4357,154,6050,0.162394223,1.190177968,0.932895282,1.516731204,0.30056712,DB0893410013573_,1.20208419,0.174102849,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sofosbuvir,DB08934
,19993,DB00381,10019211,1450,27910,512,22375,2.20709300770824e-61,2.270302079,2.048140028,2.519837067,1.90207999041348e-58,DB0038110019211_,132.9069874,0.819912897,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,19995,DB00215,10022052,42,11061,11,5265,0.078204461,1.817383202,0.918629031,3.917436003,0.175340492,DB0021510022052_,1.741025527,0.597397665,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,19996,DB00404,10022052,62,19830,14,9848,0.006810321,2.199272178,1.216774078,4.256343719,0.026220782,DB0040410022052_,3.641202979,0.788126477,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,19999,DB00215,10022061,70,11033,15,5261,0.003407632,2.225171359,1.260035068,4.189941329,0.014994798,DB0021510022061_,4.200051939,0.799833928,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,20000,DB00381,10022061,125,29235,37,22850,2.94621693542576e-08,2.640433802,1.815961544,3.922696717,5.95931605599586e-07,DB0038110022061_,14.33313993,0.970943223,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,20001,DB00404,10022061,109,19783,16,9846,2.74291644657486e-07,3.390472636,1.995221444,6.144624601,4.50609742488876e-06,DB0040410022061_,12.3100791,1.220969332,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,20003,DB00215,10028411,95,11008,28,5248,0.025611291,1.617481588,1.050018651,2.564925283,0.074861582,DB0021510028411_,2.592114448,0.480870364,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,20004,DB00381,10028411,363,28997,209,22678,0.000428722,1.358341541,1.141552559,1.619642056,0.002715737,DB0038110028411_,5.908691774,0.3062645,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,20006,DB00215,10033371,425,10678,108,5168,5.33491382417668e-10,1.904506624,1.534138991,2.381168195,1.55982435893753e-08,DB0021510033371_,17.97610752,0.644222985,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,20007,DB00404,10033371,856,19036,241,9621,1.28373528375451e-16,1.795119267,1.550789775,2.083946689,9.47374438185977e-15,DB0040410033371_,32.29025217,0.585071464,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,20008,DB08934,10033371,95,4394,82,6122,0.001616904,1.614035822,1.185251481,2.201870509,0.008167643,DB0893410033371_,4.807574909,0.478737764,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,20011,DB00169,10003598,33,38658,34,18141,0.001496207,0.455465734,0.273336943,0.758176234,0.007674464,DB0016910003598_,4.869856799,-0.786434793,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,20018,DB00169,10021015,143,38548,60,18115,0.497795515,1.120001727,0.822496151,1.541418302,0.659887341,DB0016910021015_,0.415686155,0.113330228,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,20021,DB00695,10021015,234,27815,141,20387,0.074263183,1.216379533,0.982004425,1.511067399,0.168625412,DB0069510021015_,1.78007552,0.195878851,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,20023,DB01136,10021015,31,9853,28,11087,0.434493103,1.245785381,0.722451076,2.157163622,0.60302719,DB0113610021015_,0.505792993,0.219766159,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,carvedilol,DB01136
,20025,DB11089,10021015,78,10097,48,8359,0.126526935,1.345265084,0.925982588,1.972026854,0.250839875,DB1108910021015_,1.382940491,0.296591082,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,20026,DB00169,10021027,58,38633,21,18154,0.335856546,1.297792673,0.775578886,2.252220514,0.504990889,DB0016910021027_,0.683214891,0.260664878,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,20027,DB00316,10021027,81,65393,38,36915,0.390288966,1.203261649,0.808657237,1.819192049,0.560141482,DB0031610021027_,0.579565881,0.185035911,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,20028,DB00381,10021027,35,29325,26,22861,0.897794896,1.049433895,0.613691616,1.815880838,0.956338178,DB0038110021027_,0.044643686,0.048250871,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,20031,DB00695,10021027,59,27990,27,20501,0.048680371,1.600498928,0.998559649,2.626633997,0.122575298,DB0069510021027_,2.099029756,0.470315411,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,20040,DB00688,10055181,50,6440,69,5309,0.005479114,0.597410407,0.405833939,0.87400109,0.022011084,DB0068810055181_,3.816209142,-0.515150952,NA,10055181,BK virus infection,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,20050,DB00688,10058854,48,6442,96,5282,2.93891083653421e-07,0.409994254,0.283149367,0.586869879,4.80704862092731e-06,DB0068810058854_,12.24542725,-0.891612133,NA,10058854,Cytomegalovirus viraemia,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,20056,DB00635,10005734,80,32973,73,23721,0.162814746,0.788401133,0.566554142,1.098521168,0.301124796,DB0063510005734_,1.200230495,-0.237748267,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,prednisone,DB00635
,20063,DB00635,10048962,26,33027,31,23763,0.060327377,0.603472746,0.344056172,1.050520062,0.144050247,DB0063510048962_,1.937593105,-0.5050544,NA,10048962,Brain oedema,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,20069,DB00451,10005470,32,47239,24,15395,0.002791309,0.434530875,0.247937452,0.771222731,0.0127433,DB0045110005470_,4.362749607,-0.833488278,NA,10005470,Blood creatine phosphokinase increased,10022891,Investigations,Inv,levothyroxine,DB00451
,20082,DB00115,10035664,696,17729,522,9950,1.24146446465586e-06,0.748332029,0.665277736,0.842133523,1.73628442079949e-05,DB0011510035664_,10.96117803,-0.28990851,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,20083,DB00736,10035664,365,10226,224,5329,0.063399475,0.849168422,0.714595535,1.010770995,0.149638108,DB0073610035664_,1.899535514,-0.163497735,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,20084,DB00813,10035664,282,10290,275,9893,0.897467977,0.985890286,0.830063297,1.171084697,0.956338178,DB0081310035664_,0.044643686,-0.014210202,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,fentanyl,DB00813
,20085,DB00956,10035664,151,5663,106,3361,0.191606965,0.845482035,0.652647191,1.098502806,0.338628724,DB0095610035664_,1.082850982,-0.167848358,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,hydrocodone,DB00956
,20087,DB00115,10037377,125,18300,105,10367,0.003726019,0.674446551,0.515508731,0.883752642,0.016100635,DB0011510037377_,4.128896588,-0.393862848,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,20088,DB00736,10037377,77,10514,46,5507,0.50511205,0.876771228,0.599816446,1.294245342,0.666037066,DB0073610037377_,0.406409956,-0.131509179,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,20089,DB00813,10037377,65,10507,56,10112,0.584671258,1.117069834,0.768484642,1.628282913,0.732371522,DB0081310037377_,0.31146735,0.110709037,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,20092,DB00115,10038695,93,18332,61,10411,0.400924032,0.865845839,0.619596909,1.217443363,0.570747843,DB0011510038695_,0.560807772,-0.144048401,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,20093,DB00451,10038695,273,46998,122,15297,0.004819213,0.728336697,0.585750487,0.909971626,0.019876512,DB0045110038695_,3.918216569,-0.316991842,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,20094,DB00736,10038695,69,10522,46,5507,0.202033662,0.785101206,0.532062623,1.167923478,0.351402697,DB0073610038695_,1.045822428,-0.241942644,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,20096,DB00996,10038695,281,38672,205,22220,0.010597743,0.78760708,0.654970946,0.948329674,0.037275749,DB0099610038695_,3.289412336,-0.238755943,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,20098,DB00736,10048294,39,10552,22,5531,0.788084785,0.92920893,0.536869107,1.647152736,0.885191486,DB0073610048294_,0.121951289,-0.073421667,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,esomeprazole,DB00736
,20099,DB00813,10048294,85,10487,81,10087,1,1.009356837,0.734716813,1.387527393,1,DB0081310048294_,0,0.009313333,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,fentanyl,DB00813
,20101,DB05259,10008469,167,11103,34,2694,0.419210009,1.191760856,0.818017038,1.782352768,0.588283502,DB0525910008469_,0.530546301,0.175431924,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,20102,DB05259,10008479,233,11037,44,2684,0.145082765,1.287733588,0.926909756,1.825411565,0.277184219,DB0525910008479_,1.283072945,0.252883764,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,20103,DB05259,10043528,70,11200,7,2721,0.020088213,2.429382783,1.11723338,6.270871057,0.061973728,DB0525910043528_,2.781044721,0.887637226,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glatiramer,DB05259
,20105,DB01015,10020646,89,9798,243,9138,5.86567273880795e-20,0.341601712,0.264390229,0.437993894,5.99919097041117e-18,DB0101510020646_,39.65490705,-1.074109806,male,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,sulfamethoxazole,DB01015
,20118,DB00989,10025482,41,793,21,857,0.006229438,2.109068623,1.205637586,3.791826869,0.02438796,DB0098910025482_,3.713665694,0.746246439,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,rivastigmine,DB00989
,20120,DB00989,10061422,14,820,37,841,0.002503362,0.388249388,0.192409066,0.741879455,0.011670958,DB0098910061422_,4.450651743,-0.946107393,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,rivastigmine,DB00989
,20135,DB00218,10003549,34,1408,29,921,0.299865766,0.766996922,0.450085566,1.314763279,0.465892639,DB0021810003549_,0.763800061,-0.265272491,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,moxifloxacin,DB00218
,20136,DB00218,10028813,78,1364,23,927,0.000362654,2.304055723,1.419271971,3.874628447,0.002362416,DB0021810028813_,6.048070365,0.834670928,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,moxifloxacin,DB00218
,20137,DB00218,10047700,39,1403,27,923,0.898647039,0.950302484,0.562672092,1.626320878,0.95647837,DB0021810047700_,0.044497104,-0.050974941,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,moxifloxacin,DB00218
,20139,DB01015,10001551,65,9822,57,9324,0.71650984,1.082494668,0.745908762,1.574883064,0.832381382,DB0101510001551_,0.183464552,0.079268255,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,20140,DB01015,10003481,60,9827,51,9330,0.569501337,1.116958963,0.755248532,1.657410661,0.720337936,DB0101510003481_,0.328034822,0.110609781,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,20141,DB01015,10024378,34,9853,34,9347,0.90341817,0.948627014,0.571588537,1.574482786,0.957389002,DB0101510024378_,0.043545489,-0.052739588,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,sulfamethoxazole,DB01015
,20143,DB01015,10072268,46,9841,32,9349,0.21160596,1.365606295,0.850275333,2.217907783,0.363355391,DB0101510072268_,1.012373885,0.311598502,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,sulfamethoxazole,DB01015
,20152,DB00316,10044034,178,65296,91,36862,0.484452827,1.104270435,0.852777817,1.438213143,0.648626863,DB0031610044034_,0.432897669,0.099184877,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,20153,DB00331,10044034,56,24890,43,20709,0.762008053,1.083587507,0.714920441,1.652450548,0.868143886,DB0033110044034_,0.141397811,0.080277302,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,20154,DB00476,10044034,38,17219,19,6158,0.230709211,0.715267559,0.401898516,1.314576643,0.386746914,DB0047610044034_,0.949984768,-0.335098598,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,20155,DB00722,10044034,54,25349,56,25976,1,0.988136258,0.666883286,1.463053615,1,DB0072210044034_,0,-0.011934678,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,20157,DB01076,10044034,70,25677,46,25537,0.032179509,1.513422052,1.02816523,2.246494747,0.089492505,DB0107610044034_,2.413600405,0.414373346,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,20160,DB01156,10013709,759,12863,299,6029,0.013188181,1.189767578,1.035669745,1.369553078,0.044394102,DB0115610013709_,3.11464865,0.173757976,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,20161,DB01156,10069326,123,13499,25,6303,5.70223005640011e-05,2.297182953,1.483409554,3.691000937,0.000494174,DB0115610069326_,7.612621923,0.831683569,NA,10069326,Product substitution issue,10077536,Product issues,Prod,bupropion,DB01156
,20163,DB00331,10047571,152,24794,82,20670,0.001529434,1.54532036,1.172943177,2.048308464,0.00781516,DB0033110047571_,4.851689881,0.435231242,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,metformin,DB00331
,20164,DB00175,10012378,120,8011,58,6048,0.005928978,1.561940813,1.130281399,2.179559013,0.023443881,DB0017510012378_,3.753145755,0.445929159,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,pravastatin,DB00175
,20166,DB00333,10012378,44,3027,37,3115,0.373603602,1.223718839,0.769948264,1.954725967,0.543376437,DB0033310012378_,0.609952944,0.201894451,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,methadone,DB00333
,20167,DB00656,10012378,367,11646,140,6479,0.000134975,1.458346856,1.194127086,1.789062528,0.001029546,DB0065610012378_,6.87863781,0.377303504,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,20168,DB00697,10012378,191,5905,38,1768,0.020579111,1.504810461,1.053070176,2.200741401,0.063217662,DB0069710012378_,2.761171551,0.40866695,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,tizanidine,DB00697
,20169,DB00715,10012378,154,4689,71,2216,0.884918379,1.025063216,0.7651975,1.384225618,0.952079302,DB0071510012378_,0.049106947,0.024754285,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,paroxetine,DB00715
,20171,DB11133,10012378,37,2394,18,1556,0.334349042,1.335931369,0.738457527,2.502028526,0.503429259,DB1113310012378_,0.686312075,0.289628703,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,omega-3 fatty acids,DB11133
,20172,DB13867,10012378,57,4493,25,2529,0.354574833,1.283331225,0.786647532,2.149325494,0.524420408,DB1386710012378_,0.64546161,0.249459217,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,fluticasone,DB13867
,20176,DB00230,10061284,66,19608,25,8626,0.570163636,1.161381569,0.722379109,1.922476885,0.720856239,DB0023010061284_,0.327315553,0.149610304,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,20177,DB00316,10061284,114,65360,47,36906,0.071030041,1.369590114,0.966747414,1.967552388,0.163087405,DB0031610061284_,1.813468992,0.314511508,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,20179,DB00338,10061284,52,33622,28,22244,0.42446978,1.22864357,0.761536331,2.021153104,0.593325436,DB0033810061284_,0.522012234,0.205910772,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,20180,DB00635,10061284,38,33015,25,23769,0.798819377,1.09433768,0.643427336,1.892011518,0.891356522,DB0063510061284_,0.115010795,0.090149321,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,20181,DB00656,10061284,57,11956,17,6602,0.027763632,1.851408939,1.060673835,3.398289092,0.079699347,DB0065610061284_,2.529493885,0.615946938,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,20182,DB00695,10061284,37,28012,14,20514,0.033525779,1.935404341,1.021642422,3.876747995,0.092400662,DB0069510061284_,2.381621137,0.660316266,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,20186,DB01156,10061284,56,13566,20,6308,0.387204444,1.301897901,0.768390972,2.2927423,0.557267673,DB0115610061284_,0.584709593,0.263823124,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,20190,DB00182,10027599,90,5104,25,2827,0.001610746,1.99381222,1.264740162,3.250014288,0.008142854,DB0018210027599_,4.810614588,0.690048495,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,20191,DB00182,10069326,77,5117,60,2792,0.047098044,0.700290091,0.491504482,1.001696427,0.119645509,DB0018210069326_,2.123221996,-0.356260614,NA,10069326,Product substitution issue,10077536,Product issues,Prod,amphetamine,DB00182
,20193,DB00480,10012818,77,67351,123,67539,0.001394917,0.627769466,0.465833948,0.841545302,0.007236828,DB0048010012818_,4.928572317,-0.465582273,NA,10012818,Diffuse large B-cell lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,20194,DB00051,10023003,47,25684,11,11409,0.06300137,1.89794461,0.969788731,4.059104987,0.148953543,DB0005110023003_,1.904120817,0.640771516,NA,10023003,Irritable bowel syndrome,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,20197,DB00788,10035664,188,9168,133,4928,0.017940416,0.759842509,0.60352653,0.958712933,0.056722659,DB0078810035664_,2.869581524,-0.274644092,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,naproxen,DB00788
,20198,DB01202,10035664,188,6526,149,5569,0.542281143,1.076737723,0.861131543,1.348222089,0.697538958,DB0120210035664_,0.360196913,0.073935843,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,levetiracetam,DB01202
,20199,DB14512,10035664,146,4698,63,2349,0.371373404,1.158693314,0.852781184,1.589630898,0.541008758,DB1451210035664_,0.614319811,0.147292917,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,mometasone furoate,DB14512
,20200,DB00005,10033318,39,128043,15,42404,0.637102212,0.86106585,0.464001584,1.681572355,0.774461508,DB0000510033318_,0.255587319,-0.149584297,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,etanercept,DB00005
,20201,DB00005,10039227,169,127913,57,42362,0.877943912,0.981913857,0.723103983,1.350493941,0.948285522,DB0000510039227_,0.053099639,-0.018251697,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,20202,DB00005,10060820,238,127844,64,42355,0.143142924,1.232021966,0.931096337,1.650483742,0.27423555,DB0000510060820_,1.293767869,0.208656695,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,20204,DB00571,10019211,249,4874,73,2536,1.32922764395074e-05,1.774642122,1.355561856,2.346980574,0.00013942,DB0057110019211_,8.878016832,0.573598781,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,propranolol,DB00571
,20206,DB01164,10067594,202,6322,314,7622,0.005953639,0.775611605,0.644609579,0.931570162,0.023521929,DB0116410067594_,3.749822134,-0.254103393,NA,10067594,Peritoneal dialysis complication,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium chloride,DB01164
,20207,DB08910,10002034,175,16569,188,17300,0.792136109,0.971914418,0.78563568,1.201905771,0.88743507,DB0891010002034_,0.119419921,-0.028487525,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,pomalidomide,DB08910
,20208,DB08910,10013709,224,16520,279,17209,0.048141268,0.836357913,0.697423286,1.002059425,0.121590587,DB0891010013709_,2.107095725,-0.178698632,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,20209,DB08910,10025482,428,16316,346,17142,0.000359629,1.29960244,1.123383532,1.504329714,0.002346491,DB0891010025482_,6.054834101,0.262058402,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,20210,DB00005,10005425,136,127946,47,42372,0.797660203,0.958279218,0.683022281,1.365493362,0.890637544,DB0000510005425_,0.115817731,-0.042616084,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,etanercept,DB00005
,20212,DB00005,10029216,395,127687,62,42357,3.69650023618989e-09,2.113537063,1.613217912,2.809462354,9.11895905286263e-08,DB0000510029216_,16.21032509,0.748362877,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,20213,DB00455,10001949,43,9358,15,5103,0.167871466,1.563173687,0.850348429,3.03232977,0.307953509,DB0045510001949_,1.177806453,0.446718169,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,20214,DB00722,10001949,94,25309,72,25960,0.062477225,1.339124457,0.974175332,1.847295626,0.148060573,DB0072210001949_,1.910133811,0.29201601,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,20215,DB00736,10001949,49,10542,14,5539,0.045790521,1.838914649,0.998005451,3.60977495,0.117076393,DB0073610001949_,2.144928629,0.609175533,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,20216,DB00788,10001949,41,9315,11,5050,0.040649822,2.020601837,1.018896985,4.362866864,0.106938956,DB0078810001949_,2.235497112,0.703395406,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,20217,DB01098,10001949,35,8114,24,7185,0.362167541,1.291340383,0.745788842,2.271587338,0.531834622,DB0109810001949_,0.631422699,0.255680736,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,20219,DB00555,10013968,148,6899,59,3427,0.179163023,1.245991369,0.912731197,1.719806261,0.322831195,DB0055510013968_,1.130625709,0.219931494,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lamotrigine,DB00555
,20221,DB00555,10046735,70,6977,29,3457,0.453988247,1.195958321,0.763905632,1.916688621,0.621498454,DB0055510046735_,0.475621856,0.178947806,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,lamotrigine,DB00555
,20226,DB00005,10000369,59,128023,30,42389,0.064948058,0.651174437,0.412759537,1.047157125,0.152366071,DB0000510000369_,1.88146929,-0.428977721,NA,10000369,Accident,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,20227,DB00005,10019114,53,128029,19,42400,0.785223474,0.923796136,0.537924226,1.652633071,0.88348663,DB0000510019114_,0.12387912,-0.079263864,NA,10019114,Hand fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,20229,DB00005,10061225,273,127809,94,42325,0.762491759,0.961765698,0.757930503,1.229524413,0.86846911,DB0000510061225_,0.141023261,-0.038984416,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,20230,DB00005,10040742,286,127796,92,42327,0.858234053,1.029636469,0.811094555,1.317237969,0.932350316,DB0000510040742_,0.070046659,0.029205797,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,20231,DB00005,10057392,170,127912,56,42363,1,1.005394471,0.739119571,1.385674359,1,DB0000510057392_,0,0.005379973,NA,10057392,Paranasal sinus hypersecretion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,20235,DB00374,10007554,300,17416,128,5596,0.008940938,0.753088949,0.60888835,0.935695759,0.032541202,DB0037410007554_,3.425248225,-0.283571932,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,treprostinil,DB00374
,20236,DB00820,10007554,235,11680,88,5728,0.031385048,1.309639508,1.018647143,1.696307575,0.087750641,DB0082010007554_,2.433256107,0.269751915,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,tadalafil,DB00820
,20237,DB00820,10007559,242,11673,87,5729,0.012768031,1.365180786,1.06192568,1.768639208,0.043259564,DB0082010007559_,3.140536938,0.311286864,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,tadalafil,DB00820
,20238,DB00820,10010264,570,11345,180,5636,9.21684852102634e-08,1.573107796,1.323892172,1.876352988,1.67947912218494e-06,DB0082010010264_,13.29702686,0.453053151,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,20241,DB00230,10001760,161,19513,16,8635,1.03437316176152e-11,4.453099801,2.657659639,7.984062816,3.94036210969589e-10,DB0023010001760_,21.6545783,1.493600438,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,20243,DB00273,10001760,134,8347,7,2186,2.60018350268717e-07,5.012908752,2.36214331,12.72633523,4.29983160541883e-06,DB0027310001760_,12.3569347,1.612016336,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,topiramate,DB00273
,20245,DB00335,10001760,138,8328,19,5446,4.93830903454705e-14,4.749250898,2.924242267,8.137786593,2.62494343727137e-12,DB0033510001760_,26.66596177,1.5579869,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,atenolol,DB00335
,20246,DB00381,10001760,359,29001,69,22818,1.77985879171625e-34,4.093491227,3.153842447,5.379973308,5.31631685684791e-32,DB0038110001760_,72.01194223,1.409398207,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,20247,DB00455,10001760,109,9292,17,5101,5.18257898778744e-08,3.519605484,2.097299641,6.269637761,9.99443057182633e-07,DB0045510001760_,13.81606766,1.258348905,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,loratadine,DB00455
,20248,DB00471,10001760,165,14024,17,5448,1.07002880720533e-09,3.770566691,2.281549324,6.635430509,2.95593349420832e-08,DB0047110001760_,17.33686624,1.327225306,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,20249,DB00472,10001760,96,10663,13,4299,4.26594439203109e-05,2.976858681,1.658781087,5.800604602,0.000385694,DB0047210001760_,7.860466711,1.090868611,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,fluoxetine,DB00472
,20250,DB00695,10001760,283,27766,47,20481,3.02768135702973e-28,4.441326581,3.250565132,6.187421985,5.93900033354675e-26,DB0069510001760_,58.08567159,1.490953111,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,20251,DB00736,10001760,140,10451,14,5539,3.03942246672279e-13,5.300279661,3.05108939,9.954002213,1.46455031233379e-11,DB0073610001760_,24.94688778,1.667759585,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,esomeprazole,DB00736
,20252,DB00761,10001760,143,15164,23,8602,1.88385474924628e-10,3.526754028,2.258235406,5.746808686,5.88438765109192e-09,DB0076110001760_,18.95096315,1.260377909,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,potassium chloride,DB00761
,20253,DB00904,10001760,285,22784,58,14398,3.53576222725216e-18,3.105097514,2.332225513,4.196043588,3.09791700477743e-16,DB0090410001760_,35.71063154,1.13304512,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,20255,DB01067,10001760,46,4315,10,4813,1.12149656826568e-07,5.129704334,2.549858591,11.4178855,2.01424921741465e-06,DB0106710001760_,13.11526403,1.635048023,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,glipizide,DB01067
,20256,DB01069,10001760,77,6623,11,2384,0.002185767,2.519319303,1.329575906,5.265595246,0.010463211,DB0106910001760_,4.559889916,0.923988747,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,promethazine,DB01069
,20257,DB01075,10001760,175,19773,28,11069,2.99872238433317e-12,3.498656943,2.336527194,5.42189977,1.24717433342084e-10,DB0107510001760_,22.80497047,1.252379164,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,20258,DB01254,10001760,116,3351,19,3129,1.35136964696095e-16,5.699479186,3.479910453,9.832261369,9.93587445324996e-15,DB0125410001760_,32.24262451,1.7403748,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,dasatinib,DB01254
,20259,DB00158,10037884,64,16751,39,8065,0.247651535,0.790126038,0.522010115,1.209661159,0.406934054,DB0015810037884_,0.899104137,-0.235562805,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,20260,DB00230,10037884,48,19626,18,8633,0.688226526,1.172986077,0.669455505,2.144000949,0.812014935,DB0023010037884_,0.208236546,0.1595527,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,20264,DB00335,10037884,34,8432,18,5447,0.570201317,1.220161944,0.66927148,2.297388628,0.720856239,DB0033510037884_,0.327315553,0.198983591,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,atenolol,DB00335
,20265,DB00455,10037884,54,9347,21,5097,0.22544576,1.40219125,0.831885046,2.447111829,0.380232743,DB0045510037884_,0.966971732,0.338036191,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,loratadine,DB00455
,20266,DB00471,10037884,60,14129,23,5442,1,1.0047792,0.611308349,1.704838389,1,DB0047110037884_,0,0.004767816,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,20268,DB00641,10037884,79,14045,40,12435,0.004139939,1.748561041,1.179804581,2.627955239,0.017566922,DB0064110037884_,4.041737589,0.558793187,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,20269,DB00695,10037884,104,27945,68,20460,0.487358182,1.119795596,0.816534664,1.544121005,0.6511988,DB0069510037884_,0.428940306,0.113146165,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,20270,DB00736,10037884,39,10552,26,5527,0.360603058,0.785712116,0.465771033,1.345781169,0.530540614,DB0073610037884_,0.633858767,-0.241164818,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,esomeprazole,DB00736
,20271,DB00761,10037884,56,15251,25,8600,0.355816206,1.263150056,0.77459344,2.114249091,0.525487638,DB0076110037884_,0.643428614,0.233608646,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,potassium chloride,DB00761
,20273,DB00904,10037884,106,22963,47,14409,0.055177835,1.415172098,0.994083527,2.041458391,0.134646929,DB0090410037884_,2.00509927,0.347251148,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,20277,DB01075,10037884,86,19862,43,11054,0.645435901,1.113090328,0.762649077,1.645985646,0.78117292,DB0107510037884_,0.246958745,0.107140227,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,20279,DB00158,10048959,416,16399,140,7964,0.000168549,1.443022735,1.18637913,1.763646379,0.001247798,DB0015810048959_,6.686374535,0.366740035,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,20281,DB00273,10048959,91,8390,18,2175,0.340986228,1.310551776,0.782404249,2.314941281,0.510207946,DB0027310048959_,0.672936898,0.270448251,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,20282,DB00321,10048959,125,7322,32,2818,0.038861068,1.503394219,1.009887126,2.297484926,0.103355576,DB0032110048959_,2.269580037,0.407725364,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,20283,DB00335,10048959,200,8266,105,5360,0.085634708,1.235087922,0.967850382,1.583569335,0.18774727,DB0033510048959_,1.67265853,0.211142159,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,20284,DB00455,10048959,181,9220,69,5049,0.011042366,1.436460374,1.08034452,1.928365734,0.038520051,DB0045510048959_,3.256576356,0.362182014,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,20285,DB00471,10048959,272,13917,66,5399,0.000467239,1.598800582,1.215251099,2.129244533,0.002919186,DB0047110048959_,5.836450405,0.469253712,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,20286,DB00472,10048959,124,10635,45,4267,0.608170868,1.105581437,0.778607636,1.59473709,0.750964028,DB0047210048959_,0.286397528,0.100371384,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,20287,DB00641,10048959,280,13844,184,12291,0.001646946,1.351014479,1.115860732,1.638864832,0.008293098,DB0064110048959_,4.792331663,0.300855776,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,20288,DB00695,10048959,1124,26925,567,19961,8.63281856789669e-14,1.469622641,1.325064931,1.631326856,4.47561412341547e-12,DB0069510048959_,26.13237754,0.385005661,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,20289,DB00736,10048959,204,10387,86,5467,0.092121225,1.24853543,0.963573114,1.629199735,0.19862246,DB0073610048959_,1.616349442,0.221971208,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,20290,DB00761,10048959,472,14835,191,8434,6.80026371753945e-05,1.40491074,1.18242114,1.674496604,0.000572533,DB0076110048959_,7.465439459,0.33997377,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,20291,DB00868,10048959,69,2915,23,1623,0.036192629,1.670155166,1.024101962,2.817484518,0.097927197,DB0086810048959_,2.323530965,0.512916536,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,benzonatate,DB00868
,20292,DB01039,10048959,58,2915,48,3003,0.28185103,1.244763164,0.831466089,1.871089524,0.445819469,DB0103910048959_,0.807841187,0.218945282,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,20293,DB01067,10048959,109,4252,70,4753,0.000355702,1.740493598,1.273529191,2.391996787,0.002325399,DB0106710048959_,6.063863726,0.55416875,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,20294,DB01069,10048959,129,6571,26,2369,0.005644316,1.788706706,1.163226144,2.84878929,0.022549854,DB0106910048959_,3.792026694,0.581492848,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,20295,DB01075,10048959,295,19653,103,10994,3.00180305447208e-05,1.602158109,1.274404612,2.027563388,0.000284026,DB0107510048959_,8.166445149,0.471351538,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,20296,DB01254,10048959,64,3403,38,3110,0.036151719,1.539095021,1.011286852,2.371044886,0.097844376,DB0125410048959_,2.324377067,0.431194595,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,dasatinib,DB01254
,20302,DB01373,10014184,43,22677,9,7372,0.261281207,1.553132063,0.746347579,3.625423351,0.422827552,DB0137310014184_,0.860790861,0.440273578,NA,10014184,Eczema,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,20309,DB00563,10054107,194,46452,45,15303,0.035251561,1.420205417,1.02177094,2.011691641,0.095954775,DB0056310054107_,2.34387829,0.350801521,NA,10054107,Nodule,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,20311,DB01076,10000081,320,25427,259,25324,0.013657945,1.230509148,1.040325449,1.45663536,0.04564805,DB0107610000081_,3.086794379,0.207428025,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,20313,DB01076,10003598,24,25723,45,25538,0.01123898,0.529507252,0.308472091,0.888076604,0.039084024,DB0107610003598_,3.242041487,-0.635808418,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,20317,DB01076,10013538,96,25651,47,25536,5.04596387332825e-05,2.033357778,1.419349557,2.948438094,0.000445451,DB0107610013538_,7.716422362,0.709688504,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,20318,DB01373,10013538,101,22619,13,7368,0.000648039,2.530840208,1.414103855,4.919635645,0.003840744,DB0137310013538_,5.562089189,0.928551346,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,calcium,DB01373
,20321,DB01076,10020028,36,25711,21,25562,0.062667523,1.704323517,0.968163241,3.073670391,0.148420972,DB0107610020028_,1.907702638,0.533168268,NA,10020028,Hiatus hernia,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,20324,DB00188,10021789,52,7834,63,8765,0.708263122,0.923463968,0.626258089,1.356682431,0.825757204,DB0018810021789_,0.19145449,-0.079623496,NA,10021789,Infection,10021881,Infections and infestations,Infec,bortezomib,DB00188
,20325,DB01076,10021789,212,25535,188,25395,0.269481697,1.121473972,0.916410186,1.3732459,0.432055313,DB0107610021789_,0.83920166,0.114643866,NA,10021789,Infection,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,20326,DB01373,10021789,213,22507,81,7300,0.220809713,0.852935235,0.65643607,1.117260608,0.374486776,DB0137310021789_,0.982198787,-0.159071661,NA,10021789,Infection,10021881,Infections and infestations,Infec,calcium,DB01373
,20332,DB01076,10035528,197,25550,251,25332,0.009007984,0.778169861,0.641882727,0.942304625,0.032742151,DB0107610035528_,3.419092007,-0.250810449,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,20333,DB01373,10035528,216,22504,110,7271,0.00016551,0.634458168,0.501193334,0.806933271,0.001228241,DB0137310035528_,6.702172361,-0.454983924,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,calcium,DB01373
,20334,DB05332,10035528,200,829,139,648,0.362098083,1.124624458,0.879291009,1.440994804,0.531767688,DB0533210035528_,0.631548561,0.117449164,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,romiplostim,DB05332
,20335,DB00188,10035598,39,7847,41,8787,0.822746931,1.065131352,0.668412019,1.694955133,0.905872872,DB0018810035598_,0.098856301,0.063098127,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bortezomib,DB00188
,20336,DB01076,10035598,152,25595,158,25425,0.732552627,0.955622386,0.759252378,1.202498314,0.844653601,DB0107610035598_,0.168828676,-0.045392437,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,20337,DB01373,10035598,83,22637,31,7350,0.513160139,0.869354983,0.568604795,1.360342976,0.673225736,DB0137310035598_,0.395674587,-0.140003741,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,20339,DB00188,10040753,69,7817,44,8784,0.0032803,1.762095869,1.188532772,2.636994194,0.014546216,DB0018810040753_,4.230424417,0.566503935,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,bortezomib,DB00188
,20340,DB01076,10040753,265,25482,114,25469,7.01447497940669e-15,2.323468825,1.857141942,2.921844126,4.23232174985732e-13,DB0107610040753_,28.49085549,0.843061252,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,20341,DB01373,10040753,404,22316,57,7324,8.16723687778316e-11,2.326240518,1.75696267,3.130069239,2.69354857380841e-09,DB0137310040753_,19.73240634,0.844253453,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,calcium,DB01373
,20344,DB01076,10041101,32,25715,39,25544,0.407924067,0.815061272,0.494124388,1.335565254,0.577351538,DB0107610041101_,0.549303947,-0.204491988,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,20345,DB01373,10041101,38,22682,13,7368,0.870951996,0.949527008,0.494442363,1.943707098,0.942931945,DB0137310041101_,0.058761168,-0.051791304,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,20357,DB00012,10047895,66,1580,49,1264,0.774109685,1.077547623,0.72750793,1.605115819,0.876749952,DB0001210047895_,0.131533444,0.07468774,NA,10047895,Weight decreased,10022891,Investigations,Inv,darbepoetin alfa,DB00012
,20358,DB00399,10047895,196,6796,134,4864,0.734160334,1.046869618,0.833393752,1.318253147,0.846080515,DB0039910047895_,0.167140753,0.045804395,NA,10047895,Weight decreased,10022891,Investigations,Inv,zoledronic acid,DB00399
,20366,DB01254,10028411,67,3400,41,3107,0.05160763,1.493227141,0.994295695,2.266716018,0.128056882,DB0125410028411_,2.05528072,0.400939644,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,dasatinib,DB01254
,20367,DB01192,10013709,43,725,32,522,0.904539523,0.967507595,0.589154486,1.603082904,0.957573483,DB0119210013709_,0.043352816,-0.033032004,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,oxymorphone,DB01192
,20368,DB01192,10033371,36,732,20,534,0.406673952,1.312849566,0.7304328,2.4222636,0.576242002,DB0119210033371_,0.551227564,0.272200016,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,oxymorphone,DB01192
,20370,DB00338,10007559,309,33365,216,22056,0.530931595,0.945682043,0.791495703,1.131468482,0.687854546,DB0033810007559_,0.374177879,-0.055848873,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,omeprazole,DB00338
,20371,DB00390,10007559,140,4005,134,3167,0.121866023,0.826193518,0.64415331,1.060011717,0.24406632,DB0039010007559_,1.410315287,-0.19092625,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,digoxin,DB00390
,20373,DB00722,10007559,255,25148,247,25785,0.530363819,1.058563005,0.884317938,1.267278046,0.687423901,DB0072210007559_,0.374804145,0.056912332,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,lisinopril,DB00722
,20374,DB01039,10007559,29,2944,52,2999,0.018263508,0.568166479,0.346743834,0.914592632,0.057502254,DB0103910007559_,2.855931129,-0.565340806,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,fenofibrate,DB01039
,20376,DB01175,10007559,64,10660,31,4861,0.824484111,0.94143183,0.60309973,1.498045475,0.907015945,DB0117510007559_,0.097595249,-0.060353339,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,escitalopram,DB01175
,20377,DB08932,10007559,582,18861,191,6406,0.705723648,1.034952803,0.875130209,1.228248559,0.823674283,DB0893210007559_,0.193980115,0.034355825,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,macitentan,DB08932
,20378,DB00121,10010774,114,4109,9,459,0.443869277,1.414850559,0.713134564,3.195185613,0.611877887,DB0012110010774_,0.491222548,0.347023913,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,biotin,DB00121
,20379,DB00264,10010774,491,29116,390,24502,0.413241059,1.059479839,0.924651266,1.214575486,0.582665016,DB0026410010774_,0.540142845,0.057778069,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,20380,DB00390,10010774,75,4070,55,3246,0.657161343,1.087573959,0.755272321,1.574409687,0.790458112,DB0039010010774_,0.235142613,0.08394949,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,digoxin,DB00390
,20381,DB00661,10010774,51,3477,27,1568,0.538039689,0.851860105,0.522031508,1.418514434,0.694087174,DB0066110010774_,0.365157715,-0.160332962,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,verapamil,DB00661
,20382,DB01039,10010774,46,2927,52,2999,0.684028202,0.906400066,0.593978796,1.379216799,0.809039138,DB0103910010774_,0.211907985,-0.098274497,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,fenofibrate,DB01039
,20383,DB01076,10010774,441,25306,432,25151,0.837785804,1.014582036,0.885454587,1.162596173,0.916537983,DB0107610010774_,0.087151769,0.01447674,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,20385,DB01175,10010774,185,10539,76,4816,0.459746489,1.112348452,0.845239135,1.476022679,0.627176482,DB0117510010774_,0.466527308,0.106473503,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,20386,DB08932,10010774,392,19051,120,6477,0.32999297,1.110602708,0.901143825,1.376908492,0.498641288,DB0893210010774_,0.695868303,0.104902848,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,20387,DB00121,10013968,173,4050,20,448,0.806689113,0.956839315,0.59336074,1.622215749,0.895526273,DB0012110013968_,0.110343719,-0.044119806,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,biotin,DB00121
,20388,DB00661,10013968,153,3375,48,1547,0.024093612,1.460954905,1.043591708,2.076927036,0.071457627,DB0066110013968_,2.63865064,0.379090267,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,verapamil,DB00661
,20389,DB01039,10013968,129,2844,91,2960,0.00588935,1.475297657,1.113562234,1.961164571,0.02332754,DB0103910013968_,3.758120625,0.388859771,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fenofibrate,DB01039
,20390,DB01076,10013968,1195,24552,1096,24487,0.051744616,1.087419615,0.999112575,1.183658663,0.128318056,DB0107610013968_,2.053243288,0.083807564,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,20392,DB01175,10013968,401,10323,143,4749,0.009636515,1.290074241,1.059782519,1.577471329,0.034556043,DB0117510013968_,3.365172847,0.254699768,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,20393,DB00390,10016256,326,3819,217,3084,0.034959229,1.213140349,1.011737849,1.456830386,0.095351325,DB0039010016256_,2.350187052,0.193212327,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,20394,DB00661,10016256,166,3362,67,1528,0.469042989,1.126021569,0.837151124,1.528776212,0.635390263,DB0066110016256_,0.453515882,0.118690685,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,verapamil,DB00661
,20396,DB08932,10016256,1823,17620,478,6119,8.70282249578339e-08,1.324385954,1.191757175,1.473903378,1.59688439303083e-06,DB0893210016256_,13.34745608,0.280948921,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,20398,DB00264,10022595,111,29496,142,24750,0.000969641,0.655926316,0.506711193,0.847285034,0.005371342,DB0026410022595_,5.226677541,-0.421706819,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,metoprolol,DB00264
,20399,DB00338,10022595,76,33598,63,22209,0.193524462,0.797434386,0.56321747,1.132379854,0.341089217,DB0033810022595_,1.075611203,-0.226355722,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,omeprazole,DB00338
,20400,DB00390,10022595,35,4110,63,3238,8.31192761004288e-05,0.437731234,0.280232807,0.673923157,0.000681257,DB0039010022595_,7.291571407,-0.826150177,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,digoxin,DB00390
,20401,DB00451,10022595,99,47172,60,15359,0.000285956,0.537258712,0.385786155,0.753641528,0.001939954,DB0045110022595_,6.245091106,-0.621275527,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,levothyroxine,DB00451
,20403,DB00722,10022595,52,25351,105,25927,4.10333903987812e-05,0.506499504,0.355877277,0.713084998,0.000372866,DB0072210022595_,7.894291888,-0.680231935,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,lisinopril,DB00722
,20405,DB01076,10022595,87,25660,103,25480,0.244980572,0.838739037,0.622816778,1.127361032,0.403748128,DB0107610022595_,0.906964041,-0.175855661,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,atorvastatin,DB01076
,20408,DB08932,10022595,80,19363,26,6571,0.911229559,1.044209187,0.662836563,1.695465492,0.960120631,DB0893210022595_,0.040696345,0.04325984,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,macitentan,DB08932
,20409,DB00661,10028813,176,3352,44,1551,0.0001874,1.850637988,1.315342835,2.652090693,0.001365244,DB0066110028813_,6.596422308,0.615530438,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,verapamil,DB00661
,20411,DB01175,10028813,760,9964,218,4674,1.02445032011845e-10,1.635307563,1.399010556,1.917591631,3.33676290759771e-09,DB0117510028813_,19.51826469,0.491830898,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,20412,DB08932,10028813,2239,17204,430,6167,1.7007350513315e-33,1.866469631,1.675593639,2.082665669,4.75572561960091e-31,DB0893210028813_,69.8207886,0.624048749,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,20427,DB00661,10070863,228,3300,130,1465,0.032978386,0.778671009,0.619300945,0.982118241,0.091236383,DB0066110070863_,2.39430152,-0.250166647,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,verapamil,DB00661
,20429,DB01076,10070863,156,25591,172,25411,0.347034183,0.900599593,0.719921638,1.125923603,0.516478979,DB0107610070863_,0.66072069,-0.104694523,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,20431,DB01175,10070863,243,10481,113,4779,0.862465616,0.980533697,0.779072863,1.240220343,0.936154142,DB0117510070863_,0.065975134,-0.019658267,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,20433,DB08932,10013538,70,19373,8,6589,0.001525105,2.976031024,1.429070716,7.166465608,0.007797583,DB0893210013538_,4.853941445,1.090590542,female,10013538,Diverticulitis,10021881,Infections and infestations,Infec,macitentan,DB08932
,20436,DB01012,10008479,35,10597,46,8639,0.033695385,0.620308356,0.387510334,0.985051323,0.092759283,DB0101210008479_,2.377747497,-0.477538577,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,20437,DB01012,10013968,96,10536,67,8618,0.343145253,1.171988732,0.847802829,1.628081803,0.512447526,DB0101210013968_,0.668556962,0.158702077,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cinacalcet,DB01012
,20438,DB01012,10028334,76,10556,58,8627,0.727938495,1.070908624,0.749968186,1.536086504,0.841252317,DB0101210028334_,0.172863643,0.06850747,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,cinacalcet,DB01012
,20439,DB01012,10028596,28,10604,35,8650,0.099493197,0.652606846,0.382080568,1.105155791,0.210099692,DB0101210028596_,1.560173137,-0.426780405,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,cinacalcet,DB01012
,20440,DB01012,10035664,110,10522,77,8608,0.302189929,1.168697909,0.864231688,1.587125462,0.468534317,DB0101210035664_,0.758145931,0.15589023,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cinacalcet,DB01012
,20441,DB00005,10040984,352,127730,106,42313,0.417015445,1.100062017,0.882688961,1.380543201,0.586147482,DB0000510040984_,0.534183846,0.095366558,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,20448,DB01254,10000496,27,3440,32,3116,0.359589792,0.764315107,0.439469425,1.32018939,0.529276386,DB0125410000496_,0.636244515,-0.268775132,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,dasatinib,DB01254
,20449,DB00682,10013952,108,19351,40,16324,4.23948775666291e-06,2.277539924,1.570036426,3.363130536,5.1116942974259e-05,DB0068210013952_,9.881394551,0.82309588,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,20450,DB01098,10013952,47,8102,24,7185,0.031327175,1.736619018,1.039507621,2.972662668,0.087627413,DB0109810013952_,2.434661397,0.55194013,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,20458,DB00264,10035598,219,29388,219,24673,0.074672159,0.839565226,0.692392622,1.018002527,0.169305417,DB0026410035598_,1.776050996,-0.174871109,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,20459,DB00682,10035598,201,19258,116,16248,0.001213783,1.461912158,1.156339712,1.855370035,0.006459666,DB0068210035598_,5.042177622,0.379745276,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,20460,DB01098,10035598,33,8116,39,7170,0.23742315,0.747544733,0.455076718,1.221247176,0.394791555,DB0109810035598_,0.929397362,-0.290961132,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,20461,DB01254,10035598,229,3238,272,2876,0.001819903,0.747826199,0.619970477,0.901425177,0.009003603,DB0125410035598_,4.710130417,-0.290584683,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dasatinib,DB01254
,20462,DB00264,10040844,88,29519,77,24815,0.81468827,0.960721246,0.69915045,1.322544054,0.90059403,DB0026410040844_,0.1047007,-0.040070979,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,20463,DB00381,10040844,107,29253,85,22802,0.941939767,0.981217855,0.730721951,1.32101157,0.981093944,DB0038110040844_,0.019087061,-0.01896077,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,20464,DB00682,10040844,27,19432,34,16330,0.12355396,0.667364594,0.387099748,1.140045697,0.246479647,DB0068210040844_,1.400475857,-0.404418764,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,20465,DB00695,10040844,97,27952,79,20449,0.492071563,0.898266808,0.66014953,1.225414839,0.65501299,DB0069510040844_,0.423100211,-0.107288141,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,20468,DB01254,10034474,39,3428,31,3117,0.631116321,1.143904871,0.693642194,1.901193255,0.76996484,DB0125410034474_,0.261410427,0.134447734,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,dasatinib,DB01254
,20474,DB00635,10013990,94,32959,40,23754,0.004888373,1.693657035,1.157671436,2.518235531,0.020099395,DB0063510013990_,3.907065548,0.526890117,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,20477,DB00864,10037660,222,6647,302,8090,0.227717881,0.894707954,0.746599205,1.070844783,0.383014846,DB0086410037660_,0.959681528,-0.111257922,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,20478,DB01590,10037660,129,4609,72,2795,0.606167103,1.086507412,0.804819172,1.476411576,0.749176081,DB0159010037660_,0.288781234,0.082968343,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,20481,DB01088,10007559,59,1370,15,422,0.577285388,1.211456603,0.670055918,2.32431923,0.726342542,DB0108810007559_,0.319733555,0.19182344,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,iloprost,DB01088
,20483,DB01164,10028334,59,6465,82,7854,0.445358377,0.87411516,0.613636811,1.238616577,0.613309841,DB0116410028334_,0.48888502,-0.13454315,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium chloride,DB01164
,20491,DB00264,10018358,30,29577,37,24855,0.140400253,0.681375783,0.406399869,1.13383774,0.270419919,DB0026410018358_,1.307779271,-0.383641314,NA,10018358,Glomerular filtration rate decreased,10022891,Investigations,Inv,metoprolol,DB00264
,20492,DB00451,10018358,56,47215,20,15399,0.691247188,0.913200945,0.539333554,1.607221418,0.813815434,DB0045110018358_,0.206021679,-0.090799329,NA,10018358,Glomerular filtration rate decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,20495,DB01254,10019211,217,3250,195,2953,0.918959898,1.011124983,0.823996724,1.241390869,0.964243073,DB0125410019211_,0.036411866,0.011063555,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,dasatinib,DB01254
,20497,DB00480,10016256,4001,63427,3615,64047,2.50907509128691e-06,1.117594577,1.066750701,1.170901196,3.23051867619283e-05,DB0048010016256_,10.34028276,0.111178676,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,20498,DB00480,10022437,639,66789,603,67059,0.27883185,1.064012953,0.949946844,1.191845327,0.442671772,DB0048010022437_,0.814926705,0.062047565,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,20503,DB00537,10021789,94,7463,61,4237,0.44921951,0.874883505,0.625697381,1.231004112,0.616834119,DB0053710021789_,0.483155142,-0.133664539,NA,10021789,Infection,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,20505,DB01267,10033864,47,2805,80,3635,0.14868702,0.761373066,0.517602287,1.109102214,0.282177302,DB0126710033864_,1.265219674,-0.27263181,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,20506,DB01267,10049414,77,2775,143,3572,0.010431005,0.693150342,0.516068631,0.925139531,0.036805016,DB0126710049414_,3.302121135,-0.36650836,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,20509,DB00181,10020937,242,9614,99,5772,0.001235938,1.467547546,1.154068733,1.877919245,0.006553029,DB0018110020937_,5.027827922,0.383592672,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,20510,DB00813,10020937,81,10491,43,10125,0.001521272,1.817942973,1.239551601,2.699030909,0.007782863,DB0081310020937_,4.855831039,0.597705627,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,20511,DB00181,10028330,30,9826,28,5843,0.101935527,0.637167135,0.367437794,1.107977246,0.213867055,DB0018110028330_,1.542400697,-0.45072328,NA,10028330,Muscle rigidity,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,20512,DB00813,10028330,37,10535,46,10122,0.271614101,0.772827373,0.486961156,1.219009944,0.43444042,DB0081310028330_,0.833696467,-0.257699576,NA,10028330,Muscle rigidity,10028395,Musculoskeletal and connective tissue disorders,Musc,fentanyl,DB00813
,20513,DB00813,10028334,81,10491,54,10114,0.038085784,1.446065304,1.011131553,2.082377662,0.10176729,DB0081310028334_,2.28506654,0.368846285,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,fentanyl,DB00813
,20515,DB00813,10033371,464,10108,253,9915,4.96736723339388e-14,1.798912742,1.536134249,2.110430755,2.63772217635875e-12,DB0081310033371_,26.66110538,0.58718245,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,20516,DB00813,10044565,77,10495,60,10108,0.230690592,1.235996209,0.869456654,1.764290688,0.386728035,DB0081310044565_,0.950033585,0.211877292,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,20517,DB00181,10056871,76,9780,100,5771,1.62493898932005e-07,0.448480622,0.327741624,0.611595802,2.81924233229554e-06,DB0018110056871_,12.77904239,-0.801889805,NA,10056871,Device failure,10077536,Product issues,Prod,baclofen,DB00181
,20519,DB01068,10016256,869,12894,344,6496,0.000206547,1.272695533,1.117894065,1.451350435,0.001479922,DB0106810016256_,6.515765597,0.241137118,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,20520,DB01068,10020937,188,13575,53,6787,0.000145395,1.773409518,1.299163047,2.456948755,0.001097759,DB0106810020937_,6.814484127,0.572903975,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,20521,DB00060,10033425,238,9270,39,2426,0.006627131,1.596986968,1.130882344,2.308997467,0.02564507,DB0006010033425_,3.663403924,0.468118709,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,20522,DB01068,10033425,287,13476,94,6746,0.000283723,1.528378917,1.204394962,1.954117602,0.001928538,DB0106810033425_,6.250993181,0.424207642,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,20523,DB01068,10041466,65,13698,43,6797,0.15179014,0.750116848,0.501918872,1.131000269,0.286407797,DB0106810041466_,1.25033862,-0.287526288,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,20527,DB00060,10057040,42,9466,9,2456,0.729306409,1.210769164,0.579920494,2.832826653,0.842281112,DB0006010057040_,0.171641458,0.19125583,NA,10057040,Temperature intolerance,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,20530,DB01156,10000059,141,13481,51,6277,0.138544322,1.287238709,0.926890669,1.812608612,0.267747776,DB0115610000059_,1.317709878,0.252499388,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,20545,DB01254,10051398,64,3403,67,3081,0.427373943,0.864858442,0.602046346,1.241446856,0.595927115,DB0125410051398_,0.517636909,-0.145189436,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dasatinib,DB01254
,20547,DB01202,10015037,61,6653,48,5670,0.700493271,1.083086451,0.728554528,1.61811805,0.819935235,DB0120210015037_,0.198529924,0.07981479,NA,10015037,Epilepsy,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,20549,DB06218,10016256,70,1624,47,1389,0.219813358,1.273745353,0.861233012,1.898281528,0.373218404,DB0621810016256_,0.985591496,0.241961658,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lacosamide,DB06218
,20550,DB00555,10018100,95,6952,72,3414,0.0077755,0.647968559,0.470649398,0.895386105,0.029105527,DB0055510018100_,3.536827199,-0.433913105,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,20551,DB00555,10025482,155,6892,47,3439,0.002463578,1.645515381,1.176993039,2.338078466,0.011532528,DB0055510025482_,4.462583747,0.498053637,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,20552,DB01202,10025482,131,6583,65,5653,0.000285461,1.730586201,1.272965633,2.372645968,0.001937596,DB0120210025482_,6.246307438,0.548460196,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,20557,DB01202,10061334,36,6678,39,5679,0.298496859,0.785007733,0.484177065,1.269511829,0.46447939,DB0120210061334_,0.766838093,-0.242061711,NA,10061334,Partial seizures,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,20563,DB00471,10061422,25,14164,32,5433,8.53516079224002e-06,0.299696783,0.170120776,0.522474895,9.45677235009925e-05,DB0047110061422_,9.266194329,-1.204984039,male,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,montelukast,DB00471
,20565,DB01268,10011906,142,2001,237,2893,0.211825933,0.866286322,0.69306863,1.079826547,0.36360075,DB0126810011906_,1.011698855,-0.143539799,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,20567,DB00215,10012735,589,10514,177,5099,1.68108734100939e-08,1.61379109,1.357156417,1.926452697,3.58082502094261e-07,DB0021510012735_,14.84250242,0.478586125,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,20569,DB00338,10017367,45,33629,28,22244,0.904872016,1.063056563,0.648684933,1.770187309,0.957667115,DB0033810017367_,0.043255041,0.061148309,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,20570,DB00451,10017367,61,47210,15,15404,0.354241885,1.326880043,0.744806419,2.514413066,0.524087103,DB0045110017367_,0.646097381,0.282830354,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,20572,DB00722,10017367,31,25372,23,26009,0.276383036,1.381650413,0.779699912,2.482023231,0.439829436,DB0072210017367_,0.821368274,0.323278736,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,20576,DB00682,10018836,110,19349,125,16239,0.021454357,0.738567849,0.565853342,0.962854829,0.065348834,DB0068210018836_,2.728015678,-0.303042307,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,20577,DB00722,10018836,71,25332,59,25973,0.253785095,1.233832777,0.86084819,1.774137454,0.414306019,DB0072210018836_,0.881150401,0.210125403,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,20579,DB11089,10018836,35,10140,25,8382,0.60561849,1.157266517,0.67254675,2.018890251,0.748709264,DB1108910018836_,0.289404537,0.146060773,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,20580,DB00264,10005760,35,29572,16,24876,0.048234605,1.840085179,0.991723578,3.561251906,0.121779521,DB0026410005760_,2.105543077,0.609811864,NA,10005760,Blood pressure systolic increased,10022891,Investigations,Inv,metoprolol,DB00264
,20600,DB00264,10016322,462,29145,231,24661,3.33021537983877e-11,1.692276221,1.440542025,1.992388741,1.17496256723573e-09,DB0026410016322_,20.56202955,0.526074499,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,20603,DB00668,10016322,95,9996,24,4279,0.020428008,1.694393333,1.071767598,2.777599509,0.062841618,DB0066810016322_,2.767137721,0.527324761,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,20604,DB00813,10016322,130,10442,63,10105,4.40061552849546e-06,1.996821899,1.465045052,2.745993431,5.28415619764747e-05,DB0081310016322_,9.848212518,0.691556866,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,20607,DB00264,10019301,102,29505,82,24810,0.82409737,1.045974289,0.774021961,1.417129479,0.906808974,DB0026410019301_,0.097823464,0.044948785,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,metoprolol,DB00264
,20621,DB00264,10028622,22,29585,37,24855,0.012305636,0.4995439,0.280620965,0.869608048,0.041990608,DB0026410028622_,3.170309312,-0.694059797,NA,10028622,Myoclonus,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,20625,DB00813,10028622,18,10554,35,10133,0.013389816,0.49379036,0.263096681,0.896466039,0.044926132,DB0081310028622_,3.102735646,-0.705644224,NA,10028622,Myoclonus,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,20628,DB00264,10040108,26,29581,48,24844,0.000997912,0.45492945,0.270847124,0.748324229,0.005490919,DB0026410040108_,5.204659643,-0.787612927,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,20632,DB00813,10040108,101,10471,235,9933,5.7947538572958e-15,0.407720291,0.319113865,0.517846632,3.52173653500624e-13,DB0081310040108_,28.67465201,-0.8971739,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,20635,DB00264,10041466,65,29542,39,24853,0.114505277,1.402116793,0.928183739,2.143034931,0.232882327,DB0026410041466_,1.457221987,0.33798309,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,20647,DB00264,10061422,34,29573,38,24854,0.238012024,0.751971573,0.459047574,1.227342719,0.395527208,DB0026410061422_,0.9275357,-0.285056757,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,20654,DB01254,10037087,74,3393,29,3119,5.9712463795683e-05,2.345249915,1.503049679,3.749277532,0.000513678,DB0125410037087_,7.573914597,0.85239197,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,dasatinib,DB01254
,20673,DB00987,10062959,31,2073,25,2903,0.041533612,1.736242069,0.988865144,3.077270918,0.10881202,DB0098710062959_,2.21813347,0.551723047,NA,10062959,Neutropenic colitis,10017947,Gastrointestinal disorders,Gastr,cytarabine,DB00987
,20675,DB00476,10013754,1664,15593,583,5594,0.650454695,1.023962362,0.926542829,1.132682763,0.785013507,DB0047610013754_,0.242054356,0.02367977,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,20676,DB00476,10027599,302,16955,48,6129,1.00560511406284e-08,2.274329186,1.670191447,3.156595803,2.26401117114704e-07,DB0047610027599_,15.30095756,0.821685145,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,20677,DB00476,10069326,83,17174,16,6161,0.021709509,1.860995559,1.080094659,3.408218037,0.065973115,DB0047610069326_,2.718507975,0.621111591,NA,10069326,Product substitution issue,10077536,Product issues,Prod,duloxetine,DB00476
,20678,DB01156,10069327,74,13548,29,6299,0.459736669,1.186373339,0.761785618,1.893080941,0.627176482,DB0115610069327_,0.466527308,0.17090104,NA,10069327,Product quality issue,10077536,Product issues,Prod,bupropion,DB01156
,20685,DB01267,10057880,82,2770,47,3668,3.79762925478432e-06,2.310005671,1.588773142,3.392517551,4.63958563616109e-05,DB0126710057880_,9.978300405,0.83724998,NA,10057880,Injection site nodule,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,20687,DB00734,10015832,35,4015,90,4812,8.70443461177311e-05,0.466133238,0.305320758,0.697651178,0.000708676,DB0073410015832_,7.252112042,-0.763283768,NA,10015832,Extrapyramidal disorder,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,20688,DB01267,10015832,49,2803,59,3656,0.696246227,1.083232357,0.723717778,1.615042871,0.817238577,DB0126710015832_,0.20182421,0.079949494,NA,10015832,Extrapyramidal disorder,10029205,Nervous system disorders,Nerv,paliperidone,DB01267
,20690,DB06789,10036590,188,2456,208,60,3.03679578518712e-148,0.022146551,0.015734723,0.030813277,1.59644354427287e-144,DB0678910036590_,331.104475,-3.810073507,male,10036590,Premature baby,10036585,"Pregnancy, puerperium and perinatal conditions",Preg,hydroxyprogesterone caproate,DB06789
,20693,DB01254,10008479,37,3430,40,3108,0.49150608,0.838187324,0.519787672,1.348518195,0.654619205,DB0125410008479_,0.423701579,-0.176513666,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,dasatinib,DB01254
,20694,DB00335,10035664,257,8209,197,5268,0.070505643,0.837203524,0.690347244,1.016497129,0.162202165,DB0033510035664_,1.818911788,-0.177688079,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,atenolol,DB00335
,20695,DB00758,10035664,266,8034,327,9747,0.899896835,0.986899574,0.833975624,1.167086173,0.956571579,DB0075810035664_,0.044399659,-0.013186994,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,clopidogrel,DB00758
,20696,DB00335,10061428,161,8305,111,5354,0.616000439,0.935069686,0.727797127,1.20489421,0.757244868,DB0033510061428_,0.278068607,-0.067134222,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,atenolol,DB00335
,20699,DB08895,10003239,2478,25636,558,6088,0.287856356,1.054577757,0.957511984,1.16298948,0.452845482,DB0889510003239_,0.792204312,0.053140456,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,20701,DB00158,10047513,102,16713,36,8068,0.121074744,1.367770033,0.92604392,2.0616684,0.242965185,DB0015810047513_,1.414837116,0.3131817,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,folic acid,DB00158
,20702,DB08895,10047513,105,28009,23,6623,0.822150239,1.079457224,0.681818416,1.778303802,0.905352611,DB0889510047513_,0.099430786,0.076458344,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,tofacitinib,DB08895
,20704,DB00758,10018836,40,8260,73,10001,0.037172976,0.663454127,0.438980923,0.989874804,0.099907124,DB0075810018836_,2.303514283,-0.410295566,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,20709,DB00153,10011906,179,7244,134,3305,2.59380076710636e-05,0.609479104,0.482575854,0.771242929,0.000249234,DB0015310011906_,8.297116988,-0.495150615,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,20710,DB00213,10011906,723,18172,856,12565,2.64262380298176e-25,0.584041853,0.526841189,0.647249217,4.12233630037838e-23,DB0021310011906_,51.54303707,-0.537782633,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,20711,DB00410,10011906,55,1550,62,947,0.001298144,0.54210428,0.366598999,0.799909132,0.006818209,DB0041010011906_,4.98815842,-0.612296897,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,mupirocin,DB00410
,20712,DB00567,10011906,158,4361,106,1975,0.002859469,0.675078655,0.521330589,0.876973119,0.013004784,DB0056710011906_,4.342437999,-0.39292607,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,20713,DB06228,10011906,490,15422,466,15610,0.35787391,1.06434815,0.93375822,1.213271059,0.527592794,DB0622810011906_,0.639430516,0.062362546,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,20714,DB00338,10022086,299,33375,106,22166,9.33887240502667e-09,1.873378604,1.495143273,2.362353976,2.11522844606744e-07,DB0033810022086_,15.36893283,0.627743541,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,20715,DB00586,10022086,113,6996,27,2778,0.017821389,1.66181544,1.081333706,2.637478456,0.056431178,DB0058610022086_,2.874733473,0.507910643,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,20716,DB00620,10022086,47,4781,14,3118,0.008234583,2.189209863,1.182499714,4.313275244,0.03048965,DB0062010022086_,3.490367993,0.783540685,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,20718,DB00668,10022086,86,10005,36,4267,1,1.018837735,0.681700025,1.550787258,1,DB0066810022086_,0,0.018662502,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,20720,DB00829,10022086,62,7990,20,4434,0.03682075,1.720256502,1.023335007,3.011334327,0.099219171,DB0082910022086_,2.31042403,0.542473409,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,20721,DB01104,10022086,135,15328,50,7236,0.154608088,1.274555193,0.913813556,1.802718592,0.290276686,DB0110410022086_,1.236920723,0.24259725,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,20723,DB01156,10022086,128,13494,49,6279,0.257209442,1.215491804,0.866798637,1.728401801,0.418065744,DB0115610022086_,0.872116577,0.195148772,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,20726,DB00158,10040753,380,16435,89,8015,5.01517134885135e-11,2.082169851,1.646268507,2.657565613,1.71575862913184e-09,DB0015810040753_,20.1834105,0.733410548,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,folic acid,DB00158
,20727,DB00264,10040753,321,29286,100,24792,1.01692367140743e-20,2.717268971,2.163031183,3.438310946,1.14967048184707e-18,DB0026410040753_,41.30705631,0.999627321,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,metoprolol,DB00264
,20728,DB00338,10040753,592,33082,161,22111,2.81475128169038e-27,2.457555146,2.059460224,2.94626787,5.15580051841336e-25,DB0033810040753_,55.92450493,0.899167013,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,omeprazole,DB00338
,20729,DB00586,10040753,139,6970,26,2779,0.000225211,2.131422737,1.391008006,3.384766018,0.001592382,DB0058610040753_,6.44252451,0.756789708,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,diclofenac,DB00586
,20730,DB00620,10040753,107,4721,28,3104,4.54152730046572e-06,2.512274515,1.639635494,3.967210693,5.43969218923406e-05,DB0062010040753_,9.819202989,0.921188524,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,triamcinolone,DB00620
,20731,DB00635,10040753,742,32311,189,23605,1.2876882817388e-44,2.867995954,2.43910092,3.385779933,5.99059937796538e-42,DB0063510040753_,94.91838244,1.053613512,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,prednisone,DB00635
,20733,DB00668,10040753,934,9157,240,4063,2.69906746219385e-14,1.72668922,1.489275307,2.007773636,1.49515254465259e-12,DB0066810040753_,27.22879288,0.546205829,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,epinephrine,DB00668
,20735,DB00829,10040753,84,7968,24,4430,0.003267633,1.945814735,1.221728662,3.208515838,0.014503503,DB0082910040753_,4.233365096,0.665680776,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,diazepam,DB00829
,20736,DB01104,10040753,194,15269,30,7256,1.29534094344052e-10,3.072912089,2.082106311,4.682590814,4.14209692193844e-09,DB0110410040753_,19.30206367,1.122625675,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,sertraline,DB01104
,20741,DB04868,10016256,104,1537,126,1390,0.033775968,0.746529117,0.56424804,0.986011204,0.092929431,DB0486810016256_,2.375914876,-0.292320658,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,nilotinib,DB04868
,20745,DB00335,10029354,57,8409,42,5423,0.53609564,0.875238673,0.576362883,1.338592051,0.692462905,DB0033510029354_,0.367500608,-0.13325866,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,atenolol,DB00335
,20746,DB00381,10029354,175,29185,147,22740,0.535527692,0.927581927,0.740120822,1.163819745,0.692103418,DB0038110029354_,0.368019886,-0.075174157,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,amlodipine,DB00381
,20747,DB00695,10029354,198,27851,184,20344,0.019334773,0.786047438,0.639276705,0.966845452,0.060193815,DB0069510029354_,2.810185678,-0.240738135,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,furosemide,DB00695
,20750,DB00695,10037423,334,27715,201,20327,0.027777997,1.218728281,1.019052154,1.460453365,0.079736229,DB0069510037423_,2.529031234,0.197807923,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,20751,DB01254,10037423,98,3369,81,3067,0.544543095,1.101383992,0.808687488,1.50350205,0.699501176,DB0125410037423_,0.357387803,0.096567564,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dasatinib,DB01254
,20753,DB00335,10037844,221,8245,151,5314,0.590745028,0.94329831,0.761205969,1.17146227,0.737291758,DB0033510037844_,0.304771593,-0.058372704,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,atenolol,DB00335
,20754,DB00381,10037844,784,28576,503,22384,0.000573136,1.220906547,1.088651972,1.370183852,0.003459216,DB0038110037844_,5.666713271,0.199593654,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,20755,DB00695,10037844,701,27348,436,20092,0.006853995,1.181201809,1.045125649,1.336149564,0.026369621,DB0069510037844_,3.635542633,0.166532402,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,20756,DB01254,10037844,194,3273,121,3027,0.000957903,1.482707272,1.16883493,1.886868836,0.005316962,DB0125410037844_,5.236853169,0.393869655,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dasatinib,DB01254
,20757,DB04868,10037844,127,1514,95,1421,0.109467252,1.254631996,0.944339775,1.671358199,0.225280835,DB0486810037844_,1.490407498,0.226842299,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,nilotinib,DB04868
,20764,DB00381,10040882,38,29322,41,22846,0.172974123,0.722144105,0.451827293,1.151587343,0.314754229,DB0038110040882_,1.155963171,-0.325530568,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,20765,DB00695,10040882,57,27992,36,20492,0.529287212,1.159076018,0.750243124,1.812071084,0.686570156,DB0069510040882_,0.376046865,0.147623151,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,20768,DB00335,10043554,35,8431,34,5431,0.107378771,0.663156222,0.401148891,1.097354428,0.222231486,DB0033510043554_,1.50403571,-0.410744688,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,atenolol,DB00335
,20769,DB01254,10043554,20,3447,39,3109,0.005530245,0.462584914,0.255040404,0.814666623,0.022175817,DB0125410043554_,3.80875289,-0.77092514,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,dasatinib,DB01254
,20772,DB00335,10051398,18,8448,33,5432,0.000264819,0.350749442,0.185732247,0.6420083,0.001822432,DB0033510051398_,6.307583249,-1.047683152,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,atenolol,DB00335
,20773,DB00381,10051398,84,29276,165,22722,1.26397050506261e-12,0.395126409,0.29993737,0.517199537,5.61207174418426e-11,DB0038110051398_,23.60351608,-0.928549542,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,amlodipine,DB00381
,20775,DB00335,10061822,61,8405,26,5439,0.078348004,1.518186772,0.943446262,2.506915798,0.175617388,DB0033510061822_,1.739447584,0.417516709,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,20776,DB00695,10061822,186,27863,109,20419,0.066891879,1.250520606,0.981227259,1.60012281,0.155735434,DB0069510061822_,1.859596647,0.22355995,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,20784,DB06228,10018985,220,15692,286,15790,0.004723296,0.774043118,0.645388086,0.927346346,0.019539163,DB0622810018985_,3.935334466,-0.256127698,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,20787,DB01268,10047700,208,1935,170,2960,5.03525129387321e-09,1.871466204,1.508143116,2.324708144,1.20758741112644e-07,DB0126810047700_,15.92947116,0.62672219,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,20788,DB00177,10002855,58,4742,25,2825,0.209121548,1.382061237,0.848706783,2.311332233,0.360182133,DB0017710002855_,1.021145451,0.323576035,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,valsartan,DB00177
,20789,DB00482,10002855,118,8141,48,3023,0.598116887,0.912866255,0.645594165,1.308484298,0.742999711,DB0048210002855_,0.297059623,-0.091165898,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,celecoxib,DB00482
,20790,DB00482,10003988,175,8084,54,3017,0.259746569,1.209435737,0.883951943,1.67788265,0.420953115,DB0048210003988_,0.865233818,0.190153918,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,20795,DB00177,10053762,128,4672,54,2796,0.035914453,1.418507176,1.020540664,1.994728693,0.097360911,DB0017710053762_,2.329330474,0.349605034,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,valsartan,DB00177
,20797,DB06228,10003658,316,15596,295,15781,0.327213806,1.083866013,0.920459056,1.276655585,0.495624219,DB0622810003658_,0.701937263,0.080534291,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,20798,DB06228,10035598,75,15837,59,16017,0.165933464,1.285620837,0.901224009,1.841365115,0.305365942,DB0622810035598_,1.186244412,0.251241743,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,20800,DB06228,10044565,76,15836,41,16035,0.001107189,1.876904168,1.266590456,2.816738078,0.005986928,DB0622810044565_,5.118176853,0.629623701,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,20801,DB00175,10029331,91,8040,92,6014,0.050359668,0.739903899,0.546514114,1.001605867,0.125695932,DB0017510029331_,2.073889524,-0.301234967,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,20802,DB01254,10029331,31,3436,19,3129,0.201245779,1.485708269,0.811307255,2.789577358,0.350478763,DB0125410029331_,1.048455166,0.395891607,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,dasatinib,DB01254
,20803,DB00005,10005557,225,127857,87,42332,0.237869928,0.85628957,0.66551799,1.109992471,0.39535939,DB0000510005557_,0.927960081,-0.155146677,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,etanercept,DB00005
,20804,DB00005,10017553,147,127935,61,42358,0.148315491,0.797868391,0.587992286,1.094112487,0.281671377,DB0000510017553_,1.267014217,-0.225811618,NA,10017553,Furuncle,10021881,Infections and infestations,Infec,etanercept,DB00005
,20805,DB00005,10021519,451,127631,146,42273,0.849588978,1.023137458,0.846819543,1.242094991,0.925291442,DB0000510021519_,0.077646519,0.022873846,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,20806,DB00005,10039509,127,127955,48,42371,0.431694088,0.876158729,0.623799519,1.248416465,0.600136406,DB0000510039509_,0.510598307,-0.132208007,NA,10039509,Scab,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,20811,DB00338,10037884,144,33530,77,22195,0.148055245,1.237901017,0.931779353,1.655416474,0.281319414,DB0033810037884_,1.268264551,0.213417217,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,20814,DB01076,10037884,97,25650,106,25477,0.527003976,0.908933207,0.682511569,1.209280736,0.684700245,DB0107610037884_,0.378774135,-0.095483667,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,20815,DB01373,10037884,125,22595,35,7346,0.462576982,1.161121079,0.791783836,1.742782379,0.629812021,DB0137310037884_,0.462333883,0.149385986,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,20816,DB01254,10006002,59,3408,32,3116,0.019665503,1.685639845,1.075025186,2.686878071,0.060999263,DB0125410006002_,2.7968935,0.522145222,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,dasatinib,DB01254
,20817,DB01254,10013573,79,3388,51,3097,0.062220939,1.415894376,0.979689482,2.062105176,0.147599601,DB0125410013573_,1.913252071,0.347761399,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,dasatinib,DB01254
,20822,DB01373,10074903,82,22638,15,7366,0.043598457,1.778649145,1.01727956,3.323964262,0.112816051,DB0137310074903_,2.181996656,0.575854169,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,20823,DB06643,10074903,57,52364,8,7507,1,1.021453723,0.48468101,2.480349754,1,DB0664310074903_,0,0.021226831,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,20824,DB00246,10013700,107,967,40,661,0.001455555,1.82792258,1.24164925,2.736103372,0.007501814,DB0024610013700_,4.89261038,0.60318012,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ziprasidone,DB00246
,20825,DB00502,10013700,95,1299,61,1811,4.04934901024039e-06,2.170715047,1.544263495,3.070590093,4.9105946359478e-05,DB0050210013700_,9.921530423,0.775056628,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,haloperidol,DB00502
,20827,DB01254,10033371,84,3383,51,3097,0.023378896,1.507718331,1.048335281,2.186883628,0.069747945,DB0125410033371_,2.662867316,0.410597469,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,dasatinib,DB01254
,20828,DB00060,10012174,75,9433,22,2443,0.614114649,0.882889456,0.54148995,1.495000651,0.755676399,DB0006010012174_,0.280142039,-0.124555278,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,interferon beta-1a,DB00060
,20832,DB00060,10047700,163,9345,28,2437,0.046631566,1.518054046,1.009251807,2.361242612,0.118764663,DB0006010047700_,2.130611362,0.417429282,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,interferon beta-1a,DB00060
,20833,DB00060,10048959,102,9406,19,2446,0.213546403,1.395995798,0.847715315,2.418396075,0.365695954,DB0006010048959_,1.005953018,0.333607995,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,20834,DB00108,10048959,69,10125,13,3282,0.071762211,1.720349564,0.941320643,3.397372295,0.164344998,DB0010810048959_,1.805787412,0.542527505,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,20835,DB08908,10048959,78,10595,16,3263,0.144733818,1.501311895,0.867546411,2.759249155,0.276647484,DB0890810048959_,1.285011203,0.406339323,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,20837,DB00108,10061520,83,10111,23,3272,0.57131897,1.167786817,0.727075301,1.945967261,0.72156175,DB0010810061520_,0.326337319,0.155110348,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,20839,DB00727,10030124,50,3793,53,4120,0.921196105,1.024730253,0.680306909,1.541502242,0.965093784,DB0072710030124_,0.035529997,0.02442941,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,20840,DB00758,10030124,105,8195,104,9970,0.142589498,1.228274788,0.926051407,1.629396021,0.273464299,DB0075810030124_,1.296584199,0.205610573,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,20841,DB01076,10030124,309,25438,282,25301,0.301300661,1.089819936,0.923473403,1.286585386,0.467596852,DB0107610030124_,0.760148782,0.086012486,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,20842,DB01136,10030124,183,9701,131,10984,6.38725798182194e-05,1.58164822,1.254765813,1.998300834,0.000542891,DB0113610030124_,7.518601791,0.45846748,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,20843,DB00230,10012267,47,19627,14,8637,0.213369138,1.47734476,0.799070871,2.907170873,0.36546382,DB0023010012267_,1.006587991,0.390246396,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,20845,DB01050,10008469,123,17985,37,9334,0.003286989,1.72525302,1.184962747,2.566002934,0.014573038,DB0105010008469_,4.228582196,0.545373718,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,20846,DB01075,10008469,287,19661,127,10970,0.03018112,1.260917936,1.018282595,1.568433312,0.085091789,DB0107510008469_,2.464024734,0.231839976,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,20848,DB00635,10013082,78,32975,38,23756,0.048118174,1.478754829,0.990801084,2.241320462,0.12156586,DB0063510013082_,2.107299108,0.391200402,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,20850,DB01050,10013082,68,18040,23,9348,0.07717303,1.531993549,0.941854538,2.578017042,0.173516366,DB0105010013082_,1.751483354,0.42656986,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,20851,DB01075,10013082,62,19886,28,11069,0.380398767,1.232467847,0.77641172,2.00192941,0.550435311,DB0107510013082_,0.597045838,0.209018539,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,20853,DB00635,10015150,346,32707,147,23647,3.28323910312184e-08,1.701722757,1.398051863,2.079847734,6.57523351051867e-07,DB0063510015150_,14.23478556,0.531641124,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,20855,DB01050,10015150,146,17962,69,9302,0.563896131,1.095778114,0.816509408,1.482720736,0.715779781,DB0105010015150_,0.334382728,0.091464717,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,20856,DB01075,10015150,289,19659,144,10953,0.289191861,1.118179687,0.911083597,1.377246581,0.454298712,DB0107510015150_,0.789000342,0.111702084,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,20858,DB00879,10037087,13,1764,48,3664,0.073114911,0.562599812,0.278852719,1.058361631,0.166709354,DB0087910037087_,1.791503375,-0.575186717,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,emtricitabine,DB00879
,20859,DB01050,10037087,374,17734,127,9244,2.20733012778125e-05,1.535022469,1.249815778,1.895506232,0.000217221,DB0105010037087_,8.434596267,0.428545019,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,20861,DB00635,10037867,58,32995,34,23760,0.397642909,1.228416567,0.790691396,1.935561275,0.567391757,DB0063510037867_,0.566705284,0.205725996,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,20863,DB01050,10037867,34,18074,17,9354,1,1.035078014,0.562110571,1.976726334,1,DB0105010037867_,0,0.0344768,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,20864,DB01075,10037867,45,19903,25,11072,1,1.001336441,0.600644132,1.705028654,1,DB0107510037867_,0,0.001335549,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,20867,DB01050,10046306,151,17957,65,9306,0.221286949,1.20387242,0.89337951,1.637769463,0.375138823,DB0105010046306_,0.980459126,0.185543378,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,20868,DB01075,10046306,333,19615,116,10981,7.48289665365023e-06,1.607065132,1.295386631,2.005434482,8.41986038275669e-05,DB0107510046306_,9.382332218,0.474409616,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,20870,DB00005,10028596,215,127867,185,42234,2.37334485406328e-20,0.383860198,0.313767959,0.469938791,2.5359093288233e-18,DB0000510028596_,40.51597939,-0.95747686,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,etanercept,DB00005
,20876,DB05259,10011906,92,11178,53,2675,1.38376790521777e-06,0.415437367,0.292297755,0.595694449,1.91786656412598e-05,DB0525910011906_,10.86171206,-0.878423418,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,20877,DB00115,10003658,169,18256,205,10267,2.12416365659427e-13,0.463634767,0.375397477,0.572012468,1.0445957289725e-11,DB0011510003658_,25.28480607,-0.768658177,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,cyanocobalamin,DB00115
,20878,DB00169,10003658,360,38331,300,17875,3.6185712212471e-13,0.559634366,0.478259814,0.655152034,1.71996644756745e-11,DB0016910003658_,24.78613124,-0.580471626,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,20879,DB00175,10003658,98,8033,105,6001,0.012258919,0.69726912,0.522881667,0.92912324,0.041866521,DB0017510003658_,3.173268801,-0.36058383,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,pravastatin,DB00175
,20880,DB00489,10003658,86,997,78,1056,0.372057471,1.167727651,0.838598801,1.627937346,0.541742223,DB0048910003658_,0.612964993,0.155059682,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,sotalol,DB00489
,20881,DB00497,10003658,107,19160,164,16211,1.57206114268867e-06,0.552035416,0.428183072,0.709228928,2.1482519956107e-05,DB0049710003658_,10.74827098,-0.594143075,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,oxycodone,DB00497
,20884,DB01118,10003658,205,2858,241,4468,0.003786717,1.329729777,1.091749828,1.618457107,0.016321039,DB0111810003658_,4.115300293,0.284975747,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,amiodarone,DB01118
,20885,DB06605,10003658,478,13595,435,12598,0.813569756,1.018267017,0.89031122,1.164855325,0.899877168,DB0660510003658_,0.105497005,0.018102179,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,apixaban,DB06605
,20886,DB08889,10003658,21,3144,51,3834,0.008361175,0.502186679,0.286266661,0.851969913,0.030842168,DB0888910003658_,3.47887243,-0.688783358,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,carfilzomib,DB08889
,20887,DB08910,10003658,164,16580,231,17257,0.003287458,0.738954703,0.600482312,0.907667596,0.014573038,DB0891010003658_,4.228582196,-0.302518654,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,pomalidomide,DB08910
,20888,DB00489,10013968,72,1011,57,1077,0.122604148,1.345432055,0.926755792,1.96076833,0.245161662,DB0048910013968_,1.405837443,0.296715192,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sotalol,DB00489
,20890,DB01026,10013968,58,1052,46,1022,0.365773972,1.224797386,0.809042444,1.863310761,0.535380825,DB0102610013968_,0.624776962,0.202775431,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ketoconazole,DB01026
,20891,DB01118,10013968,216,2847,263,4446,0.009139773,1.282506379,1.059630736,1.551094822,0.033127266,DB0111810013968_,3.407398592,0.248816272,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,20892,DB08889,10013968,158,3007,191,3694,0.912129713,1.01621974,0.813230887,1.268492503,0.960588545,DB0888910013968_,0.040209114,0.016089605,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carfilzomib,DB08889
,20893,DB00489,10016256,55,1028,71,1063,0.234446554,0.801103622,0.546869541,1.168393822,0.391359934,DB0048910016256_,0.938127595,-0.221764975,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sotalol,DB00489
,20894,DB01013,10016256,65,952,36,571,0.750859635,1.082914691,0.699743994,1.698569309,0.859185299,DB0101310016256_,0.151770665,0.079656194,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,clobetasol propionate,DB01013
,20895,DB01026,10016256,69,1041,60,1008,0.586469394,1.113489306,0.767456844,1.619247386,0.733679883,DB0102610016256_,0.309682472,0.107498603,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ketoconazole,DB01026
,20896,DB01118,10016256,132,2931,217,4492,0.575226393,0.932259902,0.741312282,1.168906417,0.7246849,DB0111810016256_,0.322018339,-0.070143638,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,20897,DB06605,10016256,730,13343,518,12515,1.91699114803065e-06,1.32179706,1.176239358,1.486169427,2.55129682663219e-05,DB0660510016256_,10.57632368,0.27899222,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,20898,DB00175,10030124,89,8042,80,6026,0.241947696,0.833628486,0.608196794,1.144204534,0.400112944,DB0017510030124_,0.916008413,-0.181967436,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,20900,DB00497,10030124,195,19072,136,16239,0.076407525,1.22083218,0.974703968,1.532632868,0.172163369,DB0049710030124_,1.759311432,0.199532741,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,20903,DB01234,10030124,404,31221,409,32479,0.724101839,1.027581675,0.892564802,1.182990992,0.837868324,DB0123410030124_,0.176894322,0.027208154,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,20904,DB08910,10030124,128,16616,111,17377,0.153584658,1.205957931,0.927076633,1.57078377,0.288929564,DB0891010030124_,1.241572342,0.187274215,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,20906,DB00722,10019211,1042,24361,542,25490,1.36972872097096e-40,2.011564987,1.808693307,2.239170366,5.49668998942315e-38,DB0072210019211_,85.79408744,0.69891302,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,20907,DB00722,10027599,124,25279,39,25993,4.61567510613998e-12,3.269450106,2.263665829,4.815600963,1.87226882970508e-10,DB0072210027599_,22.39869996,1.184621807,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,20908,DB00722,10044565,246,25157,183,25849,0.000963565,1.381224293,1.135132786,1.683165493,0.005344441,DB0072210044565_,5.231698305,0.322970275,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,20909,DB00722,10020751,293,25110,178,25854,2.35101792744008e-08,1.694810406,1.400772774,2.055189514,4.85249361780624e-07,DB0072210020751_,14.53860293,0.52757088,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,lisinopril,DB00722
,20910,DB00169,10011224,887,37804,369,17806,0.050172783,1.132197996,1.00025932,1.283568786,0.125342548,DB0016910011224_,2.076704909,0.124160873,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,20912,DB00437,10011224,132,6789,176,11370,0.05030652,1.256041439,0.992570336,1.586374448,0.125569239,DB0043710011224_,2.074897964,0.22796506,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,20914,DB00451,10051398,155,47116,140,15279,2.00801719724053e-17,0.359036631,0.283632264,0.454853042,1.62903493918109e-15,DB0045110051398_,34.05078862,-1.024330859,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levothyroxine,DB00451
,20915,DB01373,10051398,56,22664,116,7265,1.41810903962037e-32,0.154761141,0.110309044,0.214954742,3.70895483645984e-30,DB0137310051398_,67.76680267,-1.865872377,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,calcium,DB01373
,20919,DB09270,10013968,142,2972,116,2252,0.562897998,0.927590132,0.716084985,1.203497119,0.715048032,DB0927010013968_,0.335405561,-0.075165311,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ubidecarenone,DB09270
,20921,DB00433,10003549,335,7321,241,5779,0.284115895,1.097288463,0.923619699,1.30501715,0.448627635,DB0043310003549_,0.801562056,0.092842103,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,20922,DB00581,10003549,84,2029,68,2001,0.24785178,1.218187753,0.868737599,1.713326171,0.407161278,DB0058110003549_,0.898545911,0.197364306,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,lactulose,DB00581
,20923,DB00904,10003549,863,22206,543,13913,0.955457299,0.995775176,0.89146267,1.113045514,0.9931676,DB0090410003549_,0.006855848,-0.004233774,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,20925,DB11365,10003549,92,1553,56,1492,0.008883991,1.578096929,1.110807542,2.258804801,0.032383262,DB1136510003549_,3.430113588,0.456219646,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sennosides,DB11365
,20926,DB00181,10010774,127,9729,107,5764,0.009515678,0.70323404,0.538233731,0.920152835,0.034216085,DB0018110010774_,3.375059413,-0.352065527,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,baclofen,DB00181
,20927,DB00186,10010774,473,16428,201,9807,5.28914102592525e-05,1.404789414,1.18622495,1.668366285,0.000463494,DB0018610010774_,7.676716783,0.339887408,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,20928,DB00295,10010774,270,14393,195,9407,0.292608106,0.904964316,0.748514374,1.095709398,0.458177945,DB0029510010774_,0.780497644,-0.099859766,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,20929,DB00433,10010774,277,7379,159,5861,0.001202395,1.383713119,1.130884837,1.697679818,0.006413468,DB0043310010774_,5.049355085,0.324770552,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,20930,DB00581,10010774,115,1998,74,1995,0.003678583,1.551549467,1.1405276,2.121445166,0.015949395,DB0058110010774_,4.138334397,0.439254088,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,lactulose,DB00581
,20931,DB01101,10010774,177,7412,69,3839,0.048470191,1.32862068,0.997578238,1.786235223,0.122204322,DB0110110010774_,2.102060866,0.284141321,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,20932,DB01137,10010774,119,7653,84,5509,0.942882797,1.019785029,0.763063932,1.368035238,0.981842735,DB0113710010774_,0.018324131,0.019591849,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,20933,DB01234,10010774,997,30628,796,32092,1.72753155704381e-08,1.312371109,1.192850756,1.444236591,3.66934682641588e-07,DB0123410010774_,14.81808198,0.271835508,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,20935,DB01611,10010774,117,11796,10,2351,0.005664964,2.33177848,1.221414871,4.998291698,0.022610823,DB0161110010774_,3.789326584,0.846631273,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,20936,DB06643,10010774,303,52118,63,7452,0.008844085,0.687688808,0.522098102,0.918127033,0.032264646,DB0664310010774_,3.433783202,-0.374418857,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,20937,DB11365,10010774,105,1540,68,1480,0.015126427,1.483768371,1.073708337,2.061559192,0.049650117,DB1136510010774_,3.002754522,0.394585049,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sennosides,DB11365
,20939,DB00181,10011985,46,9810,56,5815,0.000420269,0.486925832,0.32188824,0.733368755,0.002668622,DB0018110011985_,5.926193112,-0.719643463,NA,10011985,Decubitus ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,baclofen,DB00181
,20953,DB00295,10013968,406,14257,276,9326,0.633770539,0.962216781,0.821880316,1.1278925,0.772253141,DB0029510013968_,0.25844288,-0.03851551,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,20954,DB00433,10013968,323,7333,247,5773,0.76294695,1.029499407,0.866390488,1.224412352,0.868725595,DB0043310013968_,0.140727975,0.029072672,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,20955,DB00581,10013968,124,1989,81,1988,0.004072016,1.529930726,1.138659226,2.064872513,0.017338885,DB0058110013968_,4.054803609,0.425222457,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lactulose,DB00581
,20956,DB00904,10013968,1089,21980,554,13902,4.15448010160496e-05,1.243257345,1.118825217,1.382690103,0.000376878,DB0090410013968_,7.883588032,0.217734826,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,20958,DB11365,10013968,102,1543,54,1494,0.000390155,1.828556906,1.291484029,2.613383105,0.002511686,DB1136510013968_,5.98680092,0.60352708,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sennosides,DB11365
,20973,DB00115,10017577,382,18043,160,10312,0.000976689,1.364498374,1.129708686,1.654152698,0.005404686,DB0011510017577_,5.220488885,0.31078687,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,20974,DB00295,10017577,126,14537,77,9525,0.665762592,1.072193376,0.800152167,1.444567053,0.796678137,DB0029510017577_,0.227304525,0.069706435,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,20975,DB00433,10017577,66,7590,42,5978,0.286623568,1.237661319,0.826770174,1.871099102,0.451388543,DB0043310017577_,0.795426796,0.213223566,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,20976,DB00581,10017577,37,2076,28,2041,0.319054502,1.299065768,0.770510864,2.212740276,0.487167654,DB0058110017577_,0.719146957,0.261645366,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,lactulose,DB00581
,20977,DB01101,10017577,47,7542,22,3886,0.799165226,1.100744081,0.649236973,1.921019903,0.891522704,DB0110110017577_,0.114824375,0.095986388,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,20978,DB01137,10017577,88,7684,43,5550,0.040318337,1.478111366,1.013427847,2.184793365,0.10626553,DB0113710017577_,2.241814316,0.390765168,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,20979,DB01234,10017577,223,31402,216,32672,0.47256816,1.074129702,0.886243499,1.302109462,0.638585923,DB0123410017577_,0.448499043,0.071510754,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,20981,DB01611,10017577,159,11754,27,2334,0.550751772,1.169348146,0.772000821,1.834371637,0.704818102,DB0161110017577_,0.349815521,0.156446453,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,20982,DB06643,10017577,477,51944,49,7466,0.024364946,1.399176493,1.040146637,1.919957755,0.072096431,DB0664310017577_,2.629750738,0.335883845,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,20985,DB11365,10028813,161,1484,64,1484,2.93616946620573e-10,2.514943506,1.853412057,3.44590871,8.90677604376429e-09,DB1136510028813_,18.5364535,0.92225034,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sennosides,DB11365
,20986,DB00181,10030124,82,9774,31,5840,0.031471592,1.580449521,1.032377621,2.475934858,0.087947139,DB0018110030124_,2.431019342,0.457709314,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,20987,DB00186,10030124,197,16704,81,9927,0.004964123,1.445349894,1.109001849,1.898335714,0.020346479,DB0018610030124_,3.894847398,0.368351433,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,20988,DB00295,10030124,111,14552,75,9527,0.880394343,0.968919337,0.715536701,1.318211363,0.949887748,DB0029510030124_,0.051411462,-0.031573914,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,20989,DB00433,10030124,89,7567,76,5944,0.636114733,0.919886767,0.668327645,1.26883085,0.773818154,DB0043310030124_,0.256418376,-0.083504696,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,20990,DB00581,10030124,43,2070,38,2031,0.655310102,1.110227798,0.697562968,1.773241327,0.788963159,DB0058110030124_,0.237035652,0.104565218,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,lactulose,DB00581
,20991,DB01101,10030124,63,7526,15,3893,0.005487604,2.172421349,1.220766622,4.114058638,0.022035086,DB0110110030124_,3.815119286,0.775842375,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,20992,DB01137,10030124,74,7698,65,5528,0.261242176,0.817556582,0.576806451,1.161149603,0.422799304,DB0113710030124_,0.860857671,-0.201435165,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,20994,DB01611,10030124,134,11779,13,2348,0.00989801,2.054615463,1.158947668,3.966226517,0.035265225,DB0161110030124_,3.344857938,0.720088708,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,20995,DB06643,10030124,105,52316,42,7473,2.33354125576658e-07,0.357117357,0.247243273,0.52418458,3.901853174798e-06,DB0664310030124_,12.45405894,-1.029690819,male,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,20996,DB11365,10030124,36,1609,19,1529,0.041104862,1.800199737,1.000521026,3.337866769,0.107887693,DB1136510030124_,2.226664475,0.587897624,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,sennosides,DB11365
,21004,DB00904,10030963,39,23030,21,14435,0.598766767,1.164072869,0.667846515,2.08365847,0.743578591,DB0090410030963_,0.296280814,0.15192495,NA,10030963,Oral candidiasis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,21007,DB01234,10030963,41,31584,41,32847,0.912158399,1.040000472,0.657691219,1.644434744,0.960594091,DB0123410030963_,0.040203341,0.039221167,NA,10030963,Oral candidiasis,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,21012,DB00115,10041466,58,18367,23,10449,0.164730801,1.434602095,0.870677495,2.438507174,0.303770808,DB0011510041466_,1.191481783,0.360887525,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,21013,DB00186,10041466,63,16838,46,9962,0.276578158,0.810303727,0.544844992,1.21305625,0.440014982,DB0018610041466_,0.820946502,-0.210346129,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,21016,DB00497,10041466,46,19221,31,16344,0.3602017,1.261755574,0.782645443,2.059424811,0.530058318,DB0049710041466_,0.634768245,0.232504064,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,21018,DB00904,10041466,85,22984,41,14415,0.199014312,1.30021817,0.885086867,1.937572337,0.347869739,DB0090410041466_,1.055927183,0.262532073,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,21021,DB01234,10041466,49,31576,44,32844,0.53374256,1.158352963,0.754912505,1.782162969,0.690390393,DB0123410041466_,0.370498054,0.146999137,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,21025,DB00581,10047895,54,2059,63,2006,0.349636447,0.835116742,0.566519805,1.227488993,0.519234668,DB0058110047895_,0.655399345,-0.180183754,NA,10047895,Weight decreased,10022891,Investigations,Inv,lactulose,DB00581
,21026,DB00904,10047895,543,22526,361,14095,0.387196074,0.941184,0.820967494,1.079990468,0.557267673,DB0090410047895_,0.584709593,-0.060616622,NA,10047895,Weight decreased,10022891,Investigations,Inv,ondansetron,DB00904
,21027,DB01101,10047895,164,7425,89,3819,0.687588379,0.947783916,0.725524552,1.244850358,0.811687484,DB0110110047895_,0.208639884,-0.05362874,NA,10047895,Weight decreased,10022891,Investigations,Inv,capecitabine,DB01101
,21028,DB01137,10047895,104,7668,107,5486,0.009207499,0.695413501,0.524535422,0.921683921,0.033329078,DB0113710047895_,3.401325053,-0.363248645,NA,10047895,Weight decreased,10022891,Investigations,Inv,levofloxacin,DB01137
,21029,DB01234,10047895,606,31019,664,32224,0.349717707,0.948087978,0.846880279,1.061292298,0.519297269,DB0123410047895_,0.655278787,-0.053307977,NA,10047895,Weight decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,21031,DB11365,10047895,45,1600,34,1514,0.36249352,1.252299724,0.779737867,2.027870848,0.53216466,DB1136510047895_,0.630802325,0.22498164,NA,10047895,Weight decreased,10022891,Investigations,Inv,sennosides,DB11365
,21044,DB00181,10052238,46,9810,6,5865,4.21445005515487e-05,4.583229253,1.950857168,13.14086274,0.00038166,DB0018110052238_,7.870980356,1.522403827,female,10052238,Escherichia urinary tract infection,10021881,Infections and infestations,Infec,baclofen,DB00181
,21069,DB00005,10061521,42,128040,22,42397,0.083387521,0.632146285,0.368870372,1.112050415,0.184103228,DB0000510061521_,1.692258659,-0.458634448,NA,10061521,Intervertebral disc disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,21070,DB00281,10016256,657,10801,248,5423,0.000158121,1.330095691,1.143243767,1.551243582,0.001180406,DB0028110016256_,6.741897003,0.285250888,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,21071,DB00370,10016256,266,4275,191,3472,0.208533709,1.131045873,0.930463527,1.376936842,0.35950079,DB0037010016256_,1.023038905,0.123142756,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,21072,DB00373,10016256,70,1762,54,1233,0.641851457,0.907142774,0.621984257,1.329081163,0.778419062,DB0037310016256_,0.250490259,-0.097455428,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,timolol,DB00373
,21073,DB00377,10016256,242,877,157,566,1,0.994794882,0.788268521,1.257561726,1,DB0037710016256_,0,-0.005218711,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,palonosetron,DB00377
,21074,DB00512,10016256,108,4629,79,5019,0.009540715,1.48219743,1.095435817,2.012873851,0.03429673,DB0051210016256_,3.372705262,0.393525736,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,21075,DB00673,10016256,66,601,30,311,0.650415948,1.13831748,0.71144814,1.856731805,0.785013507,DB0067310016256_,0.242054356,0.129551277,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,aprepitant,DB00673
,21076,DB00916,10016256,189,5134,89,2342,0.792737059,0.968761069,0.745312206,1.266962304,0.887629121,DB0091610016256_,0.11920128,-0.031737272,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,21077,DB01233,10016256,228,3193,110,1616,0.720847411,1.049015558,0.825056073,1.339977639,0.835410838,DB0123310016256_,0.179831654,0.04785216,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,21078,DB11089,10016256,782,9393,537,7870,0.000633398,1.220106684,1.087269052,1.369920008,0.003770127,DB1108910016256_,5.580646697,0.198938301,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,21084,DB00338,10022611,51,33623,35,22237,0.912335978,0.963676687,0.614408566,1.527331004,0.960594091,DB0033810022611_,0.040203341,-0.036999428,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,21088,DB00381,10022611,33,29327,27,22860,0.896730132,0.952678612,0.555318883,1.647671841,0.956305975,DB0038110022611_,0.04467736,-0.048477671,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,21093,DB00761,10022611,49,15258,13,8612,0.011912699,2.127387477,1.135777942,4.277040777,0.040928735,DB0076110022611_,3.195922895,0.75489469,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,21095,DB00904,10022611,39,23030,11,14445,0.019090745,2.223750105,1.116455116,4.816368353,0.059571466,DB0090410022611_,2.820578579,0.799195007,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,21106,DB00153,10029331,79,7344,56,3383,0.015426817,0.649864586,0.454474755,0.934642414,0.050393821,DB0015310029331_,2.987886714,-0.430991266,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,21107,DB00213,10029331,209,18686,158,13263,0.558218589,0.938897182,0.758987297,1.163269571,0.711200407,DB0021310029331_,0.340801022,-0.063049303,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,21108,DB00281,10029331,82,11376,40,5631,1,1.014735439,0.6861847,1.522413928,1,DB0028110029331_,0,0.014627927,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,21111,DB00377,10029331,53,1066,31,692,0.731811702,1.109810098,0.69150145,1.80803976,0.844114034,DB0037710029331_,0.169467683,0.104188918,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,palonosetron,DB00377
,21112,DB00425,10029331,154,12541,139,7345,0.000309993,0.648923684,0.511583172,0.823660129,0.002073326,DB0042510029331_,6.178601,-0.43244016,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,21115,DB00761,10029331,216,15091,150,8475,0.048382276,0.808713788,0.652421577,1.004528614,0.122052703,DB0076110029331_,2.103302339,-0.21231021,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,21116,DB00787,10029331,541,16459,537,16711,0.733546565,1.022877151,0.904275778,1.157042865,0.84546585,DB0078710029331_,0.167867501,0.022619393,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,21117,DB00916,10029331,57,5266,56,2375,5.55742632807475e-05,0.459102642,0.31080671,0.678401692,0.000483378,DB0091610029331_,7.634710784,-0.778481474,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,metronidazole,DB00916
,21118,DB01104,10029331,116,15347,54,7232,1,1.012280965,0.725922574,1.427078145,1,DB0110410029331_,0,0.012206166,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,21119,DB01233,10029331,36,3385,22,1704,0.486062117,0.823787407,0.469967135,1.474918581,0.649960453,DB0123310029331_,0.430843759,-0.193842784,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,metoclopramide,DB01233
,21120,DB01592,10029331,72,6204,48,3019,0.096628164,0.729933136,0.498274378,1.077700115,0.205707564,DB0159210029331_,1.58129971,-0.314802344,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,iron,DB01592
,21122,DB11089,10029331,155,10020,145,8262,0.292683111,0.881423625,0.696894247,1.115363961,0.45826809,DB1108910029331_,0.780300916,-0.126216923,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,docusate,DB11089
,21125,DB00186,10035226,125,16776,142,9866,1.0215904327168e-07,0.517694955,0.403265089,0.663969199,1.84680223686115e-06,DB0018610035226_,13.20205494,-0.658369099,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lorazepam,DB00186
,21126,DB00213,10035226,141,18754,179,13242,2.39936376618554e-07,0.556217499,0.442328916,0.69830191,3.99792561611327e-06,DB0021310035226_,12.42973493,-0.586595876,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pantoprazole,DB00213
,21127,DB00230,10035226,63,19611,58,8593,6.39128887033201e-05,0.475947585,0.327512479,0.692728393,0.000543058,DB0023010035226_,7.518294217,-0.742447546,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pregabalin,DB00230
,21128,DB00281,10035226,56,11402,52,5619,0.001355078,0.530715638,0.356799607,0.790696419,0.007074828,DB0028110035226_,4.951212088,-0.633528923,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lidocaine,DB00281
,21129,DB00316,10035226,405,65069,373,36580,1.21163736666344e-11,0.610375601,0.528691522,0.704929293,4.57584600326848e-10,DB0031610035226_,21.50505933,-0.493680772,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,21130,DB00338,10035226,243,33431,245,22027,3.19560932364777e-06,0.653524476,0.544511987,0.784256638,4.00365067073792e-05,DB0033810035226_,10.12571885,-0.425375293,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,omeprazole,DB00338
,21131,DB00370,10035226,29,4512,44,3619,0.008868308,0.528694977,0.318313613,0.866090087,0.032337307,DB0037010035226_,3.431533692,-0.637343617,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,mirtazapine,DB00370
,21134,DB00381,10035226,210,29150,188,22699,0.171106354,0.869824514,0.710472633,1.065548676,0.312371892,DB0038110035226_,1.163560839,-0.139463795,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,amlodipine,DB00381
,21135,DB00399,10035226,197,6795,192,4806,0.002016202,0.725735049,0.589761567,0.893144656,0.009788671,DB0039910035226_,4.626529567,-0.320570277,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,zoledronic acid,DB00399
,21136,DB00425,10035226,72,12623,96,7388,1.30811558483345e-07,0.438974623,0.318367803,0.603016377,2.31931319712292e-06,DB0042510035226_,12.97423945,-0.823313675,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,zolpidem,DB00425
,21139,DB00761,10035226,180,15127,140,8485,0.004820405,0.721214904,0.574079997,0.907513867,0.019879869,DB0076110035226_,3.918047689,-0.326818122,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,potassium chloride,DB00761
,21141,DB01104,10035226,47,15416,42,7244,0.002925722,0.5258354,0.33907464,0.817943069,0.013239351,DB0110410035226_,4.324561777,-0.642767043,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sertraline,DB01104
,21143,DB01592,10035226,50,6226,37,3030,0.065714793,0.657677857,0.420428464,1.037249927,0.153655057,DB0159210035226_,1.873045078,-0.419040047,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,iron,DB01592
,21144,DB08889,10035226,221,2944,266,3619,0.850236459,1.021321784,0.844811099,1.233783981,0.925881526,DB0888910035226_,0.077008994,0.021097655,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,carfilzomib,DB08889
,21146,DB00136,10037087,57,2035,44,1638,0.919245649,1.0427257,0.68727731,1.591106827,0.964296279,DB0013610037087_,0.036356688,0.04183815,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,calcitriol,DB00136
,21147,DB00153,10037087,205,7218,48,3391,5.61842145663709e-06,2.006315749,1.454796712,2.815320257,6.54465800964794e-05,DB0015310037087_,9.634276319,0.696300079,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ergocalciferol,DB00153
,21148,DB00213,10037087,405,18490,165,13256,4.09607407143637e-10,1.759696338,1.462638415,2.124953795,1.21931264969088e-08,DB0021310037087_,18.22239345,0.565141259,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,21149,DB00230,10037087,362,19312,113,8538,0.001081473,1.41632903,1.141687704,1.768028118,0.005875673,DB0023010037087_,5.136934693,0.348068334,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,21150,DB00281,10037087,198,11260,62,5609,0.001385019,1.590778389,1.188084306,2.155599923,0.007199689,DB0028110037087_,4.933717512,0.464223449,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,lidocaine,DB00281
,21151,DB00370,10037087,54,4487,28,3635,0.057960934,1.562285274,0.970029371,2.567172225,0.139623623,DB0037010037087_,1.968804886,0.446149668,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,mirtazapine,DB00370
,21154,DB00381,10037087,604,28756,315,22572,3.22378245312302e-09,1.505094712,1.309730464,1.732227182,8.08946269979366e-08,DB0038110037087_,16.33011843,0.408855828,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,21155,DB00399,10037087,150,6842,58,4940,3.56895473063283e-05,1.867169074,1.367005542,2.579728127,0.000330608,DB0039910037087_,8.014577653,0.62442342,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,zoledronic acid,DB00399
,21156,DB00512,10037087,130,4607,110,4988,0.066895587,1.279517907,0.981673599,1.670215875,0.155737168,DB0051210037087_,1.859585511,0.246483372,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,vancomycin,DB00512
,21158,DB00761,10037087,287,15020,91,8534,5.94852385596583e-07,1.791897593,1.408575471,2.297688172,9.03540693990983e-06,DB0076110037087_,11.61435959,0.583275166,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,potassium chloride,DB00761
,21159,DB00787,10037087,297,16703,228,17020,0.001518766,1.327337905,1.111666074,1.586491646,0.007773273,DB0078710037087_,4.857063931,0.283175361,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,21160,DB00904,10037087,437,22632,176,14280,3.08431485725807e-07,1.566638408,1.310445589,1.879395684,5.01058195445169e-06,DB0090410037087_,12.20395849,0.448932182,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,21161,DB00916,10037087,105,5218,29,2402,0.014399434,1.666611678,1.092245948,2.616462677,0.04767345,DB0091610037087_,3.043380643,0.51079263,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,metronidazole,DB00916
,21162,DB01104,10037087,294,15169,61,7225,2.76188759352901e-10,2.295540102,1.734344193,3.081030163,8.42672262285665e-09,DB0110410037087_,18.59185792,0.830968155,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,sertraline,DB01104
,21163,DB01233,10037087,75,3346,24,1702,0.052725846,1.589452797,0.987933997,2.642882556,0.130149681,DB0123310037087_,2.039070102,0.463389804,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,metoclopramide,DB01233
,21164,DB01592,10037087,161,6115,39,3028,3.46478814340596e-05,2.044050493,1.428682055,2.987743453,0.000322151,DB0159210037087_,8.040491621,0.714933375,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,iron,DB01592
,21166,DB08910,10037087,224,16520,141,17347,1.93416605517246e-06,1.668143573,1.343701036,2.076653219,2.57090036714073e-05,DB0891010037087_,10.56866929,0.511711375,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,pomalidomide,DB08910
,21168,DB11089,10037087,176,9999,85,8322,3.28009509332482e-05,1.723262659,1.320498066,2.263325755,0.000306823,DB1108910037087_,8.0892391,0.544219389,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,docusate,DB11089
,21198,DB00480,10028372,228,67200,252,67410,0.293290471,0.907599132,0.755117814,1.090345017,0.458891041,DB0048010028372_,0.778942481,-0.096952482,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,21199,DB00480,10038153,462,66966,431,67231,0.282693109,1.076134706,0.941326386,1.230534451,0.446814534,DB0048010038153_,0.805611682,0.073375645,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,21212,DB00213,10000880,27,18868,31,13390,0.082110269,0.618121176,0.354764135,1.070773186,0.181856119,DB0021310000880_,1.704539458,-0.481070763,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pantoprazole,DB00213
,21214,DB00437,10000880,43,6878,66,11480,0.691869298,1.087430948,0.721955476,1.622918562,0.814245817,DB0043710000880_,0.205492973,0.083817986,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,allopurinol,DB00437
,21227,DB00437,10045170,38,6883,76,11470,0.383654208,0.833250512,0.548391739,1.247211608,0.553689719,DB0043710045170_,0.591150823,-0.182420948,NA,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,allopurinol,DB00437
,21237,DB00230,10061024,94,19580,73,8578,0.000367153,0.564164542,0.410658815,0.777611775,0.002387882,DB0023010061024_,6.037348402,-0.572409328,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,pregabalin,DB00230
,21238,DB00335,10061024,51,8415,36,5429,0.741270213,0.913980142,0.584101063,1.443710901,0.851604605,DB0033510061024_,0.160632939,-0.089946434,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,atenolol,DB00335
,21239,DB00381,10061024,163,29197,147,22740,0.206733905,0.863623995,0.686292691,1.087536898,0.357358982,DB0038110061024_,1.02901445,-0.146617796,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,amlodipine,DB00381
,21240,DB00437,10061024,49,6872,115,11431,0.043112726,0.70877292,0.495958056,0.999938965,0.111900662,DB0043710061024_,2.190143752,-0.344220086,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,allopurinol,DB00437
,21242,DB00706,10061024,8,1067,140,15785,0.864496258,0.845362855,0.356984237,1.718521758,0.937874163,DB0070610061024_,0.064139494,-0.167989329,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,tamsulosin,DB00706
,21243,DB00758,10061024,79,8221,119,9955,0.15090472,0.803900369,0.596131786,1.07913779,0.285176921,DB0075810061024_,1.254645518,-0.218279936,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,21246,DB01234,10061024,152,31473,270,32618,8.62506771939946e-08,0.583451693,0.474792912,0.714806454,1.58372270348875e-06,DB0123410061024_,13.35573234,-0.538793619,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,21255,DB00186,10012378,358,16543,140,9868,1.95067285257309e-05,1.525327976,1.249108195,1.871032484,0.000195365,DB0018610012378_,8.540643067,0.422209453,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,21256,DB00421,10012378,125,8778,40,5212,0.00046632,1.855415037,1.287838647,2.724237317,0.002913877,DB0042110012378_,5.838270716,0.618108411,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,spironolactone,DB00421
,21257,DB00425,10012378,310,12385,141,7343,0.010285229,1.303510585,1.062461983,1.605662577,0.03638835,DB0042510012378_,3.313506617,0.265061075,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,21258,DB00437,10012378,52,6869,77,11469,0.523406235,1.127561813,0.776455975,1.626074229,0.681683327,DB0043710012378_,0.383190059,0.120057614,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,allopurinol,DB00437
,21268,DB00186,10022116,55,16846,11,9997,0.000470949,2.967062044,1.535170985,6.289940674,0.002938262,DB0018610022116_,5.829936911,1.087572253,female,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,21270,DB00425,10022116,65,12630,14,7470,0.000248645,2.745884284,1.523800764,5.301563218,0.001727173,DB0042510022116_,6.361269123,1.010103167,female,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,21272,DB00472,10022116,51,10708,12,4300,0.095464166,1.706635112,0.896504716,3.520572251,0.20396469,DB0047210022116_,1.589808388,0.534523661,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,21274,DB00421,10033371,361,8542,94,5158,1.69331878575403e-14,2.318872714,1.838039093,2.949575469,9.66533860663291e-13,DB0042110033371_,27.66506006,0.841081168,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,21275,DB00425,10033371,525,12170,206,7278,2.47303889772421e-07,1.524069391,1.291266666,1.804144243,4.11156403710821e-06,DB0042510033371_,12.40170706,0.421383988,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,21276,DB00437,10033371,184,6737,211,11335,0.000187007,1.467119331,1.194526907,1.800746051,0.001362969,DB0043710033371_,6.598089896,0.383300839,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,21277,DB01017,10033371,59,1410,18,883,0.008224856,2.052113527,1.184243061,3.722595888,0.030460115,DB0101710033371_,3.491337157,0.718870251,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,minocycline,DB01017
,21285,DB00421,10047899,250,8653,105,5147,0.003134489,1.416210788,1.120037616,1.801103288,0.014020256,DB0042110047899_,4.267252164,0.347984846,NA,10047899,Weight increased,10022891,Investigations,Inv,spironolactone,DB00421
,21286,DB00425,10047899,216,12479,64,7420,3.69972878937338e-07,2.00670562,1.509318145,2.699801124,5.89378007446542e-06,DB0042510047899_,12.04161299,0.696494382,NA,10047899,Weight increased,10022891,Investigations,Inv,zolpidem,DB00425
,21287,DB00437,10047899,124,6797,130,11416,0.000242582,1.601935242,1.24001379,2.06884113,0.001690869,DB0043710047899_,6.382512782,0.471212425,NA,10047899,Weight increased,10022891,Investigations,Inv,allopurinol,DB00437
,21290,DB00186,10051055,135,16766,86,9922,0.624827038,0.928980687,0.702813126,1.233523143,0.764509819,DB0018610051055_,0.26852041,-0.07366733,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,lorazepam,DB00186
,21291,DB00421,10051055,73,8830,30,5222,0.10154589,1.439020854,0.927367352,2.284072503,0.213232172,DB0042110051055_,1.545373697,0.36396292,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,spironolactone,DB00421
,21292,DB00425,10051055,78,12617,82,7402,0.00027694,0.558093302,0.403437641,0.771444611,0.001890989,DB0042510051055_,6.270655431,-0.583229122,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,zolpidem,DB00425
,21293,DB00437,10051055,46,6875,122,11424,0.006392949,0.626547547,0.43569837,0.887560169,0.024909378,DB0043710051055_,3.692510923,-0.467530614,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,allopurinol,DB00437
,21300,DB00682,10017626,38,19421,29,16335,0.714544678,1.102093788,0.661639092,1.853727199,0.830796075,DB0068210017626_,0.185370912,0.097211814,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,warfarin,DB00682
,21304,DB00331,10003988,460,24486,273,20479,6.95682636752112e-06,1.40923034,1.209205401,1.644889142,7.90234144642579e-05,DB0033110003988_,9.445766364,0.343043697,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,21306,DB00331,10010774,362,24584,305,20447,0.875553411,0.987154293,0.844324058,1.154755713,0.946510165,DB0033110010774_,0.054973569,-0.012928926,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,21307,DB01276,10010774,30,1987,21,1490,0.887063995,1.071243892,0.590553096,1.977088859,0.953054449,DB0127610010774_,0.048083242,0.068820489,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,exenatide,DB01276
,21308,DB00331,10012680,31,24915,38,20714,0.11622417,0.678249672,0.407906433,1.119822026,0.235467995,DB0033110012680_,1.446180276,-0.388239811,NA,10012680,Diabetic neuropathy,10029205,Nervous system disorders,Nerv,metformin,DB00331
,21310,DB01276,10013573,42,1975,25,1486,0.384933606,1.263957324,0.74881157,2.174527006,0.55504854,DB0127610013573_,0.58869971,0.234247533,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,exenatide,DB01276
,21311,DB01276,10013968,40,1977,25,1486,0.527975647,1.202567776,0.708275879,2.078260153,0.685443898,DB0127610013968_,0.377688624,0.184459084,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,exenatide,DB01276
,21312,DB00331,10017885,194,24752,101,20651,0.000102927,1.602528153,1.25268246,2.060514726,0.00081797,DB0033110017885_,7.108685128,0.471582478,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,21315,DB01276,10020772,31,1986,28,1483,0.508066264,0.826782606,0.477489668,1.437363688,0.668695696,DB0127610020772_,0.402426186,-0.190213489,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,exenatide,DB01276
,21316,DB00331,10024378,54,24892,62,20690,0.092599798,0.723951669,0.492916635,1.060415419,0.199393975,DB0033110024378_,1.612472637,-0.323030644,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,metformin,DB00331
,21320,DB00331,10027457,48,24898,52,20700,0.192333504,0.767448034,0.507183042,1.159135565,0.339579255,DB0033110027457_,1.080047912,-0.26468451,NA,10027457,Metastases to liver,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metformin,DB00331
,21322,DB00331,10033610,59,24887,58,20694,0.402956092,0.845860118,0.578323506,1.23757917,0.572716115,DB0033110033610_,0.557365121,-0.167401278,NA,10033610,Pancreatic carcinoma metastatic,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metformin,DB00331
,21324,DB00331,10037377,132,24814,153,20599,0.005026514,0.71620773,0.562659419,0.910659872,0.020550928,DB0033110037377_,3.884849171,-0.333785029,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,21328,DB00331,10051055,121,24825,162,20590,7.24112119130275e-05,0.619509167,0.485045558,0.789450499,0.000604135,DB0033110051055_,7.411712146,-0.478827781,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,metformin,DB00331
,21338,DB08908,10011906,372,10301,177,3102,2.09720439882441e-06,0.632918956,0.525315643,0.764807418,2.76420587423411e-05,DB0890810011906_,10.49617208,-0.457412897,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,21347,DB08815,10053762,104,1350,58,645,0.383682487,0.856777252,0.606566655,1.219624248,0.5537146,DB0881510053762_,0.591105888,-0.15457731,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lurasidone,DB08815
,21373,DB13961,10037087,238,9219,96,6318,7.98364176063823e-06,1.698974221,1.331938011,2.181277279,8.93358976919437e-05,DB1396110037087_,9.323107161,0.530024669,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,fish oil,DB13961
,21374,DB14513,10037087,184,6993,57,3507,0.001407814,1.618815253,1.193069916,2.225225901,0.007292223,DB1451310037087_,4.920946898,0.481694556,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,magnesium,DB14513
,21378,DB06643,10044016,88,52333,17,7498,0.239961724,0.741663663,0.437602895,1.330942524,0.397842432,DB0664310044016_,0.921699252,-0.298859422,NA,10044016,Tooth abscess,10021881,Infections and infestations,Infec,denosumab,DB06643
,21383,DB06643,10048762,111,52310,18,7497,0.594862264,0.883819798,0.533834622,1.54681496,0.740549143,DB0664310048762_,0.300363282,-0.123502086,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,denosumab,DB06643
,21397,DB06643,10014020,108,52313,7,7508,0.033976242,2.214300962,1.038161867,5.640995111,0.093353423,DB0664310014020_,2.371362738,0.794936761,NA,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,denosumab,DB06643
,21398,DB00381,10028164,59,29301,19,22868,0.000528215,2.4234262,1.42392841,4.306507675,0.003229061,DB0038110028164_,5.735563794,0.885182324,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,amlodipine,DB00381
,21404,DB00421,10028813,716,8187,242,5010,8.9179236442528e-16,1.810474761,1.5558823,2.112221687,5.98742332028569e-14,DB0042110028813_,30.44653015,0.59358911,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,21405,DB00471,10028813,876,13313,192,5273,1.91407807965356e-14,1.807062477,1.538802504,2.13060516,1.08313331159728e-12,DB0047110028813_,27.55116306,0.591702586,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,21412,DB00381,10033433,178,29182,80,22807,3.01394738508104e-05,1.738906156,1.327561379,2.294588462,0.000285072,DB0038110033433_,8.162767538,0.55325627,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,21413,DB00421,10033433,160,8743,28,5224,1.59142503829162e-11,3.414075343,2.271001195,5.308458562,5.85862844978924e-10,DB0042110033433_,21.25793541,1.227906693,female,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,spironolactone,DB00421
,21414,DB00471,10033433,42,14147,9,5456,0.118324159,1.799758457,0.862771187,4.207900529,0.23870297,DB0047110033433_,1.432535304,0.587652466,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,21416,DB00999,10033433,54,21376,8,12231,5.33127863957442e-05,3.862116649,1.825970899,9.399563024,0.000466379,DB0099910033433_,7.670512446,1.351215388,female,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,21417,DB06643,10033433,671,51750,67,7448,0.003579864,1.441366403,1.11862185,1.883877705,0.015599588,DB0664310033433_,4.160510803,0.365591554,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,21424,DB00381,10043224,36,29324,16,22871,0.068544681,1.754839506,0.949012454,3.387750011,0.158683894,DB0038110043224_,1.840841141,0.562377403,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,21442,DB08828,10047895,66,696,117,1025,0.267117955,0.830834482,0.595480311,1.151594858,0.42939152,DB0882810047895_,0.845386143,-0.185324683,NA,10047895,Weight decreased,10022891,Investigations,Inv,vismodegib,DB08828
,21445,DB00060,10013950,44,9464,10,2455,0.866079381,1.141364984,0.564928865,2.547153851,0.939291974,DB0006010013950_,0.062628907,0.132224901,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,interferon beta-1a,DB00060
,21446,DB08908,10013950,73,10600,30,3249,0.198691574,0.745856681,0.480423461,1.184422207,0.347481688,DB0890810013950_,1.057043313,-0.293221814,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,21452,DB00316,10019842,38,65436,28,36925,0.30557628,0.765845167,0.457694479,1.295825038,0.47236371,DB0031610019842_,0.750006019,-0.266775261,NA,10019842,Hepatomegaly,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,21456,DB00316,10059570,114,65360,65,36888,0.938079866,0.989836402,0.723420232,1.364252789,0.97796491,DB0031610059570_,0.022281489,-0.0102156,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,acetaminophen,DB00316
,21470,DB00193,10040979,53,19267,19,8683,0.445354897,1.257085894,0.731585702,2.25013457,0.613309841,DB0019310040979_,0.48888502,0.22879626,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,21471,DB00476,10040979,88,17169,22,6155,0.157824298,1.433920307,0.889679145,2.40586068,0.294553023,DB0047610040979_,1.222296247,0.360412167,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,21472,DB00996,10040979,105,38848,56,22369,0.682473561,1.079647534,0.773021311,1.52186803,0.80796081,DB0099610040979_,0.213241724,0.07663463,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,21473,DB00476,10047895,311,16946,114,6063,0.824233794,0.976058746,0.783434238,1.223129992,0.906883161,DB0047610047895_,0.097741657,-0.024232504,NA,10047895,Weight decreased,10022891,Investigations,Inv,duloxetine,DB00476
,21479,DB09072,10054112,65,6406,32,2503,0.306889482,0.793664541,0.510724272,1.255997957,0.473929847,DB0907210054112_,0.746695971,-0.2310944,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,sodium oxybate,DB09072
,21486,DB00273,10003988,153,8328,22,2171,0.00797141,1.812834555,1.151614118,2.985740447,0.029705566,DB0027310003988_,3.51642083,0.594891673,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,topiramate,DB00273
,21490,DB00316,10010214,47,65427,32,36921,0.413992045,0.828839054,0.517728968,1.342490201,0.583267307,DB0031610010214_,0.539109696,-0.187729287,NA,10010214,Compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,21494,DB00273,10013573,306,8175,51,2142,0.002640201,1.572022754,1.160692716,2.166696629,0.012181444,DB0027310013573_,4.407841485,0.452363168,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,21495,DB00953,10013573,63,1634,6,226,0.4561165,1.452016732,0.621117227,4.153477592,0.623454092,DB0095310013573_,0.472480146,0.37295344,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,rizatriptan,DB00953
,21497,DB00953,10033371,81,1616,6,226,0.175038447,1.887490438,0.817030277,5.3564319,0.317510477,DB0095310033371_,1.147244462,0.635248136,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,rizatriptan,DB00953
,21498,DB06204,10033371,39,773,18,361,1,1.011848713,0.556237451,1.906631108,1,DB0620410033371_,0,0.011779066,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,tapentadol,DB06204
,21500,DB00316,10034835,52,65422,31,36922,0.819677541,0.946680631,0.595360439,1.528382724,0.903936442,DB0031610034835_,0.100996228,-0.054793485,NA,10034835,Pharyngitis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,21523,DB00588,10061818,126,16398,78,8390,0.206559566,0.826527673,0.617479907,1.112161585,0.35712808,DB0058810061818_,1.029660794,-0.19052188,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,21524,DB06228,10061818,103,15809,68,16008,0.007107982,1.533743308,1.117350394,2.116804479,0.02711659,DB0622810061818_,3.607609548,0.427711354,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,21525,DB00374,10025127,114,17602,42,5682,0.455420025,0.876205849,0.609257396,1.281407215,0.622890798,DB0037410025127_,0.47338406,-0.132154229,NA,10025127,Lung transplant,10042613,Surgical and medical procedures,Surg,treprostinil,DB00374
,21526,DB00374,10059168,124,17592,57,5667,0.029749715,0.700796858,0.507364052,0.978056088,0.084164382,DB0037410059168_,2.474983467,-0.355537222,NA,10059168,Oxygen consumption increased,10022891,Investigations,Inv,treprostinil,DB00374
,21531,DB00820,10013709,131,11784,204,5612,2.72485262365945e-26,0.305842672,0.243081562,0.383660569,4.6060877534399e-24,DB0082010013709_,53.73466338,-1.184684453,male,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,21532,DB08868,10013709,268,8934,67,2444,0.543812509,1.094238065,0.830985892,1.458001464,0.698944394,DB0886810013709_,0.35818409,0.09005829,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,21538,DB01062,10028813,218,4268,51,1694,0.000639509,1.696455702,1.238488398,2.361116325,0.003800473,DB0106210028813_,5.572629653,0.528541193,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,oxybutynin,DB01062
,21539,DB08868,10028813,375,8827,76,2435,0.016290032,1.36109463,1.056428244,1.772838085,0.052573876,DB0886810028813_,2.945535944,0.308289251,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fingolimod,DB08868
,21540,DB00996,10033371,1679,37274,655,21770,1.23909046649139e-18,1.49712796,1.364870724,1.643629165,1.13879345845197e-16,DB0099610033371_,36.71139216,0.403548579,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,21541,DB01062,10033371,146,4340,47,1698,0.289622558,1.21530429,0.864765937,1.734878888,0.454776364,DB0106210033371_,0.787949488,0.19499449,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,21542,DB00316,10033775,693,64781,261,36692,9.59174118892825e-09,1.503885291,1.301705703,1.741710135,2.16783247765244e-07,DB0031610033775_,15.34436784,0.408051953,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,21543,DB00820,10033775,77,11838,47,5769,0.249193541,0.798421629,0.547570056,1.174984169,0.408599372,DB0082010033775_,0.895020134,-0.225118464,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,21544,DB00996,10033775,509,38444,208,22217,2.05462202707493e-05,1.414193649,1.200134997,1.671188803,0.00020449,DB0099610033775_,8.494992761,0.346559509,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,21545,DB01062,10033775,57,4429,12,1733,0.058050283,1.858444414,0.982937666,3.815342268,0.139781209,DB0106210033775_,1.96767687,0.619739801,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,21546,DB08868,10033775,305,8897,71,2440,0.250068088,1.178096914,0.903418544,1.553709308,0.409726644,DB0886810033775_,0.892265064,0.163900352,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,21547,DB00820,10047513,111,11804,56,5760,0.868519304,0.967255246,0.694175576,1.360848207,0.941383885,DB0082010047513_,0.060404268,-0.033292862,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,tadalafil,DB00820
,21548,DB08868,10047513,305,8897,96,2415,0.215771548,0.862428331,0.680261764,1.101311937,0.368334657,DB0886810047513_,0.99876336,-0.148003228,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,fingolimod,DB08868
,21549,DB00820,10047700,845,11070,178,5638,6.11172711822002e-30,2.417658708,2.047520911,2.867404583,1.34432424520848e-27,DB0082010047700_,61.87390604,0.882799596,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,21550,DB01062,10047700,116,4370,31,1714,0.062882688,1.467630943,0.97578711,2.266797166,0.148746531,DB0106210047700_,1.905511554,0.383649497,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,oxybutynin,DB01062
,21551,DB08868,10047700,152,9050,41,2470,1,1.011831785,0.710226784,1.470110649,1,DB0886810047700_,0,0.011762336,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,fingolimod,DB08868
,21552,DB06403,10061024,162,21309,40,6621,0.212928251,1.258373965,0.884475778,1.828346364,0.364934573,DB0640310061024_,1.008037193,0.229820384,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,ambrisentan,DB06403
,21554,DB00363,10013968,42,4586,46,6842,0.156603053,1.362137174,0.873233778,2.119864697,0.292861246,DB0036310013968_,1.228056344,0.309054918,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clozapine,DB00363
,21555,DB00559,10017944,74,9585,15,3291,0.066731825,1.693711791,0.961948701,3.182265043,0.15544451,DB0055910017944_,1.861466463,0.526922447,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,21556,DB00682,10017944,104,19355,60,16304,0.022425519,1.460083232,1.051838658,2.042538784,0.067563156,DB0068210017944_,2.694692473,0.378493443,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,21557,DB00682,10019196,111,19348,121,16243,0.047553689,0.770146761,0.589304883,1.005674945,0.120488599,DB0068210019196_,2.116200149,-0.261174184,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,21565,DB08932,10016173,974,18469,285,6312,0.023907326,1.16797408,1.019226333,1.341619378,0.071026172,DB0893210016173_,2.644706853,0.155270692,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,21566,DB08932,10021097,1236,18207,396,6201,0.317612555,1.063029824,0.944936248,1.197784623,0.485487672,DB0893210021097_,0.722601384,0.061123156,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,macitentan,DB08932
,21567,DB08932,10035598,312,19131,97,6500,0.491677436,1.092840522,0.865871721,1.389598845,0.654764485,DB0893210035598_,0.423479674,0.08878029,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,21568,DB00363,10001488,27,4601,44,6844,0.808346977,0.912777172,0.542699375,1.509606906,0.896571526,DB0036310001488_,0.109177206,-0.091263489,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,21569,DB00363,10019070,29,4599,34,6854,0.368101132,1.271117464,0.745954113,2.152998304,0.53781375,DB0036310019070_,0.620242969,0.239896406,NA,10019070,"Hallucination, auditory",10037175,Psychiatric disorders,Psych,clozapine,DB00363
,21582,DB01164,10010305,30,6494,44,7892,0.482802265,0.828608202,0.502371568,1.349847835,0.647065147,DB0116410010305_,0.435308299,-0.188007851,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,calcium chloride,DB01164
,21583,DB01164,10048294,40,6484,54,7882,0.677814066,0.900482159,0.582068531,1.382707329,0.804755555,DB0116410048294_,0.217216706,-0.104824926,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,calcium chloride,DB01164
,21584,DB00374,10003988,428,17288,94,5630,0.000447414,1.482726101,1.180940062,1.877943835,0.002815389,DB0037410003988_,5.872654856,0.393882353,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,21585,DB06403,10003988,366,21105,71,6590,0.000173045,1.609543723,1.243267793,2.109124097,0.001277045,DB0640310003988_,6.663206452,0.475950737,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,21586,DB06403,10012735,1689,19782,395,6266,8.21727578060636e-08,1.354369733,1.208574727,1.520582669,1.51410697034882e-06,DB0640310012735_,13.40068475,0.303336205,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,21587,DB06403,10016256,1344,20127,356,6305,0.00617933,1.182635002,1.047743919,1.337498153,0.024231492,DB0640310016256_,3.720102185,0.167745001,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,21588,DB00374,10016807,996,16720,305,5419,0.406720807,1.058373639,0.92654982,1.211639827,0.57625358,DB0037410016807_,0.551207471,0.056733427,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,treprostinil,DB00374
,21589,DB06403,10016825,664,20807,171,6490,0.028433578,1.211162204,1.019797366,1.444749462,0.081236115,DB0640310016825_,2.510395361,0.191580397,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,ambrisentan,DB06403
,21590,DB00374,10019211,2719,14997,670,5054,4.33951511558973e-12,1.367621344,1.248730161,1.499187442,1.76706668959374e-10,DB0037410019211_,22.45653,0.313072985,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,21591,DB00374,10022004,112,17604,34,5690,0.846758556,1.064717505,0.718703415,1.614388197,0.923031089,DB0037410022004_,0.080092363,0.062709511,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,21592,DB06403,10022004,109,21362,30,6631,0.617626195,1.127820833,0.746231129,1.752365525,0.758594637,DB0640310022004_,0.276287719,0.120287305,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,21593,DB00374,10022437,278,17438,97,5627,0.50544361,0.924806803,0.729876827,1.180044145,0.666365919,DB0037410022437_,0.405916332,-0.078170425,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,treprostinil,DB00374
,21594,DB06403,10022437,277,21194,114,6547,0.011806903,0.750601076,0.600243863,0.943633542,0.04063962,DB0640310022437_,3.203011836,-0.286880958,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ambrisentan,DB06403
,21595,DB00374,10025482,1113,16603,262,5462,1.17171267893262e-06,1.397461883,1.216028023,1.610591247,1.64741737179694e-05,DB0037410025482_,11.01371663,0.334657651,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,21596,DB00374,10028391,132,17584,44,5680,0.860285113,0.969062325,0.683167704,1.397980185,0.934173106,DB0037410028391_,0.06809352,-0.03142635,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,21597,DB06403,10028391,136,21335,22,6639,0.003434124,1.923528207,1.219035443,3.173487638,0.015094641,DB0640310028391_,4.193415517,0.654161108,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,21598,DB00374,10028411,350,17366,101,5623,0.346711318,1.122050329,0.89478886,1.417331954,0.516129977,DB0037410028411_,0.661396653,0.115157663,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,21599,DB06403,10028411,444,21027,145,6516,0.590099543,0.948893567,0.783220679,1.155004487,0.736743033,DB0640310028411_,0.305516113,-0.052458639,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,21600,DB00374,10028810,447,17269,107,5617,0.004296506,1.358778471,1.095561514,1.697733835,0.018105597,DB0037410028810_,4.011534185,0.306586113,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,treprostinil,DB00374
,21601,DB06403,10028810,550,20921,90,6571,1.3957252629704e-09,1.919268404,1.53060239,2.430397065,3.76659533235903e-08,DB0640310028810_,17.09450925,0.651944074,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,21602,DB00374,10033425,839,16877,264,5460,0.719695462,1.028160652,0.891159287,1.189200634,0.83455146,DB0037410033425_,0.180860872,0.027771431,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,21603,DB06403,10033425,763,20708,234,6427,0.909413619,1.01199793,0.870561257,1.179879433,0.959303996,DB0640310033425_,0.041547262,0.011926525,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,21604,DB00374,10043521,228,17488,56,5668,0.070509264,1.319553145,0.979606054,1.803576217,0.162203397,DB0037410043521_,1.818904193,0.277293153,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,21605,DB06403,10043521,124,21347,20,6641,0.004284688,1.928682118,1.195558505,3.269406391,0.018063035,DB0640310043521_,4.013887685,0.656836929,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,21606,DB00374,10068319,274,17442,56,5668,0.001217952,1.589913948,1.186926245,2.16272099,0.006475954,DB0037410068319_,5.039659329,0.463679894,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,21607,DB06403,10068319,202,21269,33,6628,0.000279162,1.907413004,1.313892284,2.849447098,0.001903693,DB0640310068319_,6.263959553,0.645747876,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,21609,DB00341,10012174,171,11234,79,4989,0.782537279,0.961284811,0.730467826,1.27423198,0.881673092,DB0034110012174_,0.125933936,-0.039484544,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,cetirizine,DB00341
,21611,DB00863,10012174,156,10517,100,5740,0.211430969,0.851437609,0.656732616,1.108072148,0.363089283,DB0086310012174_,1.013106516,-0.160829054,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ranitidine,DB00863
,21613,DB00043,10012378,44,6369,7,2293,0.03857416,2.262919035,1.009237404,5.96305131,0.102790125,DB0004310012378_,2.275065992,0.816655588,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,omalizumab,DB00043
,21614,DB00661,10012378,58,3470,13,1582,0.019612779,2.033808352,1.097467239,4.058428989,0.060868045,DB0066110012378_,2.79904696,0.709910071,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,verapamil,DB00661
,21615,DB00745,10012378,141,2436,54,1029,0.573570324,1.102937394,0.793227937,1.552038998,0.723413352,DB0074510012378_,0.323774502,0.097976979,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,modafinil,DB00745
,21616,DB00999,10012378,402,21028,146,12093,1.23704868201663e-06,1.583447025,1.305226274,1.929593212,1.73140706106534e-05,DB0099910012378_,10.96399106,0.459604132,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,21618,DB00043,10012735,78,6335,27,2273,1,1.036554878,0.659535888,1.675265938,1,DB0004310012735_,0,0.035902597,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,omalizumab,DB00043
,21619,DB00341,10012735,637,10768,217,4851,0.000454294,1.322454788,1.127452046,1.555700035,0.002851271,DB0034110012735_,5.859990455,0.279489698,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,21620,DB00588,10012735,926,15598,373,8095,4.74766462774755e-05,1.288402148,1.137734016,1.461303556,0.000422667,DB0058810012735_,7.76892646,0.253402806,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,21621,DB00661,10012735,142,3386,45,1550,0.036214952,1.444413383,1.020216066,2.078914919,0.097958325,DB0066110012735_,2.323213147,0.367703276,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,verapamil,DB00661
,21622,DB00745,10012735,83,2494,32,1051,0.755667109,1.093007808,0.71377354,1.710108184,0.862950453,DB0074510012735_,0.147398002,0.088933353,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,modafinil,DB00745
,21623,DB00043,10013700,58,6355,16,2284,0.4267956,1.302776729,0.737024435,2.433190145,0.595499766,DB0004310013700_,0.518354282,0.264497932,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,omalizumab,DB00043
,21624,DB00341,10013700,260,11145,56,5012,1.36021499666934e-07,2.087851797,1.555613004,2.844753926,2.40438810944543e-06,DB0034110013700_,12.93821511,0.736135689,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,cetirizine,DB00341
,21625,DB00471,10013700,286,13903,56,5409,7.01763473064319e-07,1.986888957,1.484785709,2.70029432,1.04776216356124e-05,DB0047110013700_,11.46626885,0.686570077,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,montelukast,DB00471
,21626,DB00588,10013700,345,16179,94,8374,9.84679312777678e-09,1.899600857,1.505685636,2.416186892,2.22070319488299e-07,DB0058810013700_,15.32027175,0.641643789,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,fluticasone propionate,DB00588
,21627,DB00661,10013700,227,3301,36,1559,2.7771546930649e-11,2.977484747,2.075781549,4.381408414,9.8979797459998e-10,DB0066110013700_,20.73352026,1.091078899,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,verapamil,DB00661
,21628,DB00745,10013700,66,2511,12,1071,0.00539551,2.345429995,1.25045781,4.787410611,0.021730021,DB0074510013700_,3.82906052,0.852468752,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,modafinil,DB00745
,21629,DB00999,10013700,604,20826,171,12068,5.35545894573096e-18,2.046733012,1.721601449,2.443488143,4.63816271461411e-16,DB0099910013700_,35.30704317,0.716244869,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,hydrochlorothiazide,DB00999
,21631,DB00043,10022095,59,6354,14,2286,0.183006546,1.516063449,0.834313044,2.946521588,0.32766807,DB0004310022095_,1.115754166,0.416117139,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,21632,DB00471,10022095,66,14123,9,5456,0.001703472,2.832659867,1.404052332,6.471500757,0.008520604,DB0047110022095_,4.765268044,1.041216153,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,21633,DB00588,10022095,69,16455,16,8452,0.002697872,2.215024968,1.271276046,4.09171971,0.012396394,DB0058810022095_,4.390349642,0.795263676,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,21656,DB00043,10047924,183,6230,69,2231,0.717180329,0.949761578,0.713030605,1.277253221,0.832810627,DB0004310047924_,0.182949001,-0.051544296,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omalizumab,DB00043
,21659,DB00999,10047924,100,21330,30,12209,0.001331995,1.907919432,1.256821013,2.974839208,0.00697093,DB0099910047924_,4.966006613,0.646013345,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,21661,DB08877,10035664,97,3192,170,3059,2.44337532511696e-06,0.546868093,0.419535184,0.709564414,3.15437794432153e-05,DB0887710035664_,10.36413415,-0.603547652,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ruxolitinib,DB08877
,21664,DB00005,10042727,80,128002,20,42399,0.298138629,1.324931375,0.80364286,2.284396405,0.464045825,DB0000510042727_,0.767771972,0.281360666,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,21665,DB00437,10005557,48,6873,89,11457,0.595609982,0.89902416,0.618492704,1.292941181,0.74122358,DB0043710005557_,0.299452972,-0.10644537,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,allopurinol,DB00437
,21666,DB00451,10005557,326,46945,149,15270,0.000888749,0.711678292,0.583984596,0.870578149,0.005001558,DB0045110005557_,5.298005842,-0.340129307,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,levothyroxine,DB00451
,21668,DB00451,10037437,46,47225,17,15402,0.661256253,0.882485027,0.496202998,1.642561377,0.793354286,DB0045110037437_,0.23148539,-0.125013456,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,21669,DB00480,10037437,255,67173,304,67358,0.041988603,0.841128061,0.709096819,0.997120703,0.109681533,DB0048010037437_,2.210174262,-0.173011359,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,21670,DB00437,10038435,134,6787,194,11352,0.205810553,1.155292271,0.918032688,1.450403209,0.35619624,DB0043710038435_,1.032273464,0.14435336,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,allopurinol,DB00437
,21671,DB00451,10038435,311,46960,190,15229,3.55271629855674e-11,0.530853806,0.441320118,0.639809933,1.24843780625085e-09,DB0045110038435_,20.50137282,-0.633268614,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,21672,DB08934,10012735,250,4239,337,5867,0.763477306,1.026754269,0.864062887,1.218802462,0.869056626,DB0893410012735_,0.140346993,0.026402632,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sofosbuvir,DB08934
,21674,DB01164,10013700,68,6456,64,7872,0.159546319,1.295507484,0.90567098,1.855037664,0.2968343,DB0116410013700_,1.214581209,0.258902498,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,calcium chloride,DB01164
,21675,DB00983,10011224,234,3267,100,1640,0.207356522,1.174648904,0.918152427,1.511333058,0.358058481,DB0098310011224_,1.027058952,0.160969297,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,formoterol,DB00983
,21676,DB00983,10025482,104,3397,21,1719,4.52944855086469e-05,2.505710526,1.550317101,4.232887508,0.000406258,DB0098310025482_,7.808522528,0.918572338,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,formoterol,DB00983
,21677,DB00983,10028813,150,3351,37,1703,4.90291599447739e-05,2.060047219,1.421759484,3.052509872,0.000434428,DB0098310028813_,7.741479708,0.722728905,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,formoterol,DB00983
,21679,DB00331,10005557,762,24184,632,20120,0.978208113,1.00308498,0.89996698,1.11828626,1,DB0033110005557_,0,0.003080231,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,metformin,DB00331
,21680,DB00471,10005557,96,14093,36,5429,1,1.027285766,0.692661624,1.553676614,1,DB0047110005557_,0,0.026920146,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,montelukast,DB00471
,21681,DB00588,10005557,107,16417,62,8406,0.463147459,0.883674489,0.639586385,1.229987044,0.630278589,DB0058810005557_,0.461593352,-0.123666509,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,21682,DB01261,10005557,250,3531,180,3123,0.041016196,1.228368502,1.003821217,1.505490054,0.10769261,DB0126110005557_,2.228474318,0.205686868,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,sitagliptin,DB01261
,21683,DB08882,10005557,32,965,46,947,0.106941058,0.682810288,0.416874958,1.106370257,0.221549754,DB0888210005557_,1.50710809,-0.38153822,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,linagliptin,DB08882
,21684,DB00331,10022523,86,24860,222,20530,2.67318911305741e-21,0.319921618,0.246282862,0.412438657,3.20112873971362e-19,DB0033110022523_,42.58561329,-1.139679256,male,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,21690,DB00811,10011906,33,2765,55,4101,0.662158617,0.889900226,0.558235256,1.399038222,0.794021198,DB0081110011906_,0.23064512,-0.116645928,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,21692,DB08934,10011906,59,4430,117,6087,0.025266876,0.692916008,0.496615461,0.957954316,0.07409794,DB0893410011906_,2.602367554,-0.366846487,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,21693,DB00921,10003046,80,5765,22,4881,6.01375042502225e-07,3.078339786,1.897386909,5.192376885,9.12916141621194e-06,DB0092110003046_,11.60403672,1.124390421,female,10003046,Application site irritation,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,21694,DB00921,10003053,350,5495,95,4808,1.7226246507165e-27,3.223033508,2.553387255,4.100914485,3.21128999603427e-25,DB0092110003053_,56.3979546,1.170322999,female,10003053,Application site pruritus,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,21695,DB00921,10003054,177,5668,65,4838,1.85757309740774e-09,2.324068823,1.734915693,3.146317539,4.87775313340284e-08,DB0092110003054_,16.83599605,0.843319453,NA,10003054,Application site rash,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,21705,DB00193,10005557,103,19217,44,8658,0.858186512,1.054667458,0.73345038,1.538784698,0.932317936,DB0019310005557_,0.070081389,0.053225512,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,tramadol,DB00193
,21708,DB01069,10005557,43,6657,15,2380,1,1.024894633,0.556965918,1.989877295,1,DB0106910005557_,0,0.02458981,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,promethazine,DB01069
,21723,DB01069,10017955,45,6655,32,2363,0.003895057,0.499342,0.309601248,0.813994522,0.016696277,DB0106910017955_,4.092569502,-0.694464047,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,promethazine,DB01069
,21724,DB00193,10038435,148,19172,85,8617,0.075606701,0.782561722,0.59460184,1.035561641,0.170790834,DB0019310038435_,1.767315665,-0.245182482,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,tramadol,DB00193
,21727,DB01069,10038435,61,6639,50,2345,1.8670863532982e-05,0.430966041,0.290718674,0.641450483,0.000188068,DB0106910038435_,8.578706547,-0.841725983,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,promethazine,DB01069
,21730,DB01069,10040047,97,6603,50,2345,0.037590324,0.689005399,0.483183466,0.992974538,0.100766065,DB0106910040047_,2.294953634,-0.372506171,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,promethazine,DB01069
,21734,DB00421,10021015,82,8821,29,5223,0.017581347,1.67418379,1.082504455,2.656577338,0.055876393,DB0042110021015_,2.884613299,0.515325757,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,spironolactone,DB00421
,21735,DB00497,10021015,85,19182,50,16325,0.038073172,1.44678108,1.007802026,2.096219721,0.101749106,DB0049710021015_,2.285245245,0.369341144,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,21737,DB00761,10021015,218,15089,119,8506,0.819295958,1.032700859,0.820839403,1.304448172,0.903682015,DB0076110021015_,0.101277733,0.032177563,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,21738,DB00787,10021015,86,16914,32,17216,3.9983912000045e-07,2.735516924,1.802396761,4.245651361,6.32546636212743e-06,DB0078710021015_,11.97092679,1.006320421,female,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,acyclovir,DB00787
,21739,DB01137,10021015,77,7695,30,5563,0.004114157,1.855448969,1.200522942,2.935635685,0.017475857,DB0113710021015_,4.046934929,0.618126698,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,levofloxacin,DB01137
,21753,DB00555,10012374,41,7006,20,3466,1,1.01417952,0.579652485,1.830135257,1,DB0055510012374_,0,0.014079931,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,21754,DB01088,10011906,150,1279,72,365,0.001270209,0.594729429,0.434978216,0.818469263,0.006695566,DB0108810011906_,5.006309698,-0.519648719,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,iloprost,DB01088
,21755,DB00181,10037377,63,9793,45,5826,0.369453482,0.832898278,0.558345783,1.251378766,0.539100385,DB0018110037377_,0.617853482,-0.182843759,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,baclofen,DB00181
,21756,DB00181,10000059,80,9776,33,5838,0.078975729,1.447668588,0.952481338,2.245591528,0.176632804,DB0018110000059_,1.733682254,0.369954392,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,baclofen,DB00181
,21757,DB00370,10000059,36,4505,20,3643,0.224495498,1.455515306,0.818700957,2.658575885,0.379147632,DB0037010000059_,0.96982962,0.37536,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,mirtazapine,DB00370
,21758,DB00575,10000059,59,5185,39,3790,0.681335489,1.105820456,0.723871326,1.706004783,0.807380174,DB0057510000059_,0.213960626,0.100587554,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,clonidine,DB00575
,21759,DB00656,10000059,125,11888,51,6568,0.069149172,1.354120828,0.968849774,1.9169356,0.159801828,DB0065610000059_,1.833820805,0.303152408,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,21760,DB00704,10000059,56,4300,57,5137,0.447386182,1.173670083,0.795103913,1.731889421,0.615151613,DB0070410000059_,0.485886517,0.160135663,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,naltrexone,DB00704
,21761,DB00996,10000059,444,38509,226,22199,0.135583347,1.1325382,0.961879038,1.336405448,0.263566045,DB0099610000059_,1.333451298,0.124461309,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,21762,DB01015,10000059,106,9781,57,9324,0.000498775,1.772700046,1.271240686,2.494186094,0.003085502,DB0101510000059_,5.781040841,0.572503834,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,21763,DB00370,10012735,233,4308,142,3521,0.006701475,1.341040504,1.078469421,1.672213341,0.025871819,DB0037010012735_,3.654600972,0.293445808,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,mirtazapine,DB00370
,21764,DB00575,10012735,255,4989,133,3696,0.001325463,1.420332718,1.14200379,1.772883252,0.00694573,DB0057510012735_,4.969628134,0.350891153,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,clonidine,DB00575
,21765,DB01015,10012735,519,9368,377,9004,5.27002598515023e-05,1.323143513,1.152821336,1.519751059,0.000462204,DB0101510012735_,7.679503526,0.280010355,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,21766,DB00575,10028813,343,4901,151,3678,4.91395539488468e-08,1.70458607,1.396569036,2.088286825,9.5218074127935e-07,DB0057510028813_,13.86451097,0.533322307,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,clonidine,DB00575
,21767,DB00656,10028813,761,11252,256,6363,4.48572031271787e-13,1.680990387,1.452081098,1.950922924,2.10360675146814e-11,DB0065610028813_,24.58478265,0.519383136,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,21770,DB00203,10028334,198,13680,98,8840,0.031079833,1.305570088,1.018182922,1.683213313,0.08708528,DB0020310028334_,2.44086741,0.266639794,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,21771,DB00005,10040952,80,128002,14,42405,0.02329461,1.892945359,1.064954646,3.618028205,0.069579413,DB0000510040952_,2.665286543,0.638134007,NA,10040952,Skin warm,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,21772,DB00982,10019211,190,3174,82,2019,0.00395341,1.473802863,1.124476329,1.945503565,0.016913766,DB0098210019211_,4.079627413,0.387846042,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,isotretinoin,DB00982
,21773,DB00490,10013709,193,3877,102,1474,0.011149355,0.719425432,0.55864285,0.930839577,0.03882114,DB0049010013709_,3.248790339,-0.329302397,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,21774,DB00490,10044565,80,3990,44,1532,0.067888329,0.698156632,0.47492878,1.037955561,0.157532087,DB0049010044565_,1.848126112,-0.359311801,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,buspirone,DB00490
,21776,DB00108,10002855,129,10065,30,3265,0.114115852,1.394828194,0.929531065,2.154818212,0.23230844,DB0010810002855_,1.459689309,0.332771249,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,natalizumab,DB00108
,21777,DB00108,10003549,296,9898,124,3171,0.015317861,0.764765111,0.615556081,0.95464686,0.050137596,DB0010810003549_,2.99298413,-0.268186536,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,21778,DB00108,10019465,43,10151,8,3287,0.190255574,1.740349597,0.807780577,4.290504446,0.336872196,DB0010810019465_,1.088051661,0.554086011,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,21780,DB00115,10037087,468,17957,151,10321,2.42565891094651e-10,1.781346973,1.477276154,2.157951321,7.46149145397647e-09,DB0011510037087_,18.71351052,0.577369804,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,21781,DB00268,10037087,65,2910,28,1517,0.440641998,1.210093181,0.762150183,1.96682954,0.608952415,DB0026810037087_,0.496015151,0.190697366,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ropinirole,DB00268
,21782,DB00404,10037087,373,19519,103,9759,3.26445996283942e-08,1.810553881,1.449809286,2.277771242,6.54510527255791e-07,DB0040410037087_,14.23937817,0.59363281,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,21783,DB00471,10037087,387,13802,91,5374,8.27645496174835e-06,1.655846167,1.311540971,2.108845651,9.21612449352067e-05,DB0047110037087_,9.291970853,0.504312157,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,21784,DB00540,10037087,44,2439,14,1077,0.317348841,1.387728316,0.742563075,2.754160416,0.485150543,DB0054010037087_,0.723296039,0.327668105,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,nortriptyline,DB00540
,21785,DB00567,10037087,114,4405,58,2023,0.560602675,0.90268381,0.649300861,1.266369106,0.713227651,DB0056710037087_,0.337954623,-0.102382942,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,cephalexin,DB00567
,21786,DB00697,10037087,131,5965,21,1785,0.006163075,1.866519324,1.167594479,3.125945453,0.024177319,DB0069710037087_,3.722340329,0.624075373,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,tizanidine,DB00697
,21787,DB00706,10037087,26,1049,229,15696,0.018449846,1.69876312,1.081136791,2.568832499,0.057960343,DB0070610037087_,2.847996238,0.52990041,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,tamsulosin,DB00706
,21788,DB00736,10037087,250,10341,100,5453,0.019735077,1.318287433,1.03878058,1.68348425,0.061157333,DB0073610037087_,2.794305501,0.276333495,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,esomeprazole,DB00736
,21789,DB00745,10037087,43,2534,11,1072,0.175486003,1.653524288,0.834544155,3.569360358,0.317960267,DB0074510037087_,1.145828849,0.502908942,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,modafinil,DB00745
,21792,DB01202,10037087,79,6635,36,5682,0.00180045,1.879155209,1.249710946,2.874665403,0.008921637,DB0120210037087_,4.719275838,0.630822319,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,levetiracetam,DB01202
,21793,DB01609,10000081,46,1538,31,1312,0.354461658,1.26572263,0.780374211,2.078014334,0.524312024,DB0160910000081_,0.645668306,0.235643208,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,deferasirox,DB01609
,21794,DB01609,10012735,179,1405,129,1214,0.146889443,1.198887545,0.937973999,1.535534498,0.279635003,DB0160910012735_,1.274270086,0.181394081,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,deferasirox,DB01609
,21795,DB01609,10028813,92,1492,66,1277,0.324694894,1.192997756,0.852143331,1.677701927,0.49316074,DB0160910028813_,0.706920113,0.176469262,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,deferasirox,DB01609
,21796,DB01609,10047700,51,1533,45,1298,0.91713072,0.959595687,0.625399832,1.47667079,0.96313474,DB0160910047700_,0.03756196,-0.041243243,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,deferasirox,DB01609
,21797,DB00482,10013573,174,8085,76,2995,0.249569471,0.848144832,0.64190881,1.12939342,0.409062672,DB0048210013573_,0.893886903,-0.164703865,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,21798,DB00437,10018627,89,6832,171,11375,0.301981581,0.866541059,0.661843483,1.128164836,0.46829415,DB0043710018627_,0.758658654,-0.143245786,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,allopurinol,DB00437
,21800,DB00437,10047700,204,6717,190,11356,5.80404893402064e-09,1.81506705,1.478752461,2.228876267,1.3762690683873e-07,DB0043710047700_,15.79871939,0.596122409,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,21801,DB01020,10013700,51,1762,36,1842,0.082354121,1.48082127,0.942574351,2.348265802,0.182274308,DB0102010013700_,1.702242539,0.392596846,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,isosorbide mononitrate,DB01020
,21802,DB08895,10035664,607,27507,141,6505,0.887895995,1.018062746,0.844481846,1.234132638,0.953558579,DB0889510035664_,0.04755442,0.017901553,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,21803,DB00363,10061422,23,4605,49,6839,0.184428731,0.697120713,0.404770351,1.168148813,0.329449338,DB0036310061422_,1.11033269,-0.360796694,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,21825,DB00177,10002034,86,4714,59,2791,0.387185588,0.863033538,0.610302312,1.227528339,0.557267673,DB0017710002034_,0.584709593,-0.147301726,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,valsartan,DB00177
,21826,DB00196,10002034,96,4987,60,3225,0.86883084,1.034688739,0.739284893,1.457993786,0.94160196,DB0019610002034_,0.060172642,0.034100646,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,fluconazole,DB00196
,21827,DB00598,10002034,32,1556,35,993,0.031250409,0.583619423,0.34732863,0.977538625,0.087468534,DB0059810002034_,2.436476157,-0.538506181,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,labetalol,DB00598
,21829,DB01039,10002034,51,2922,49,3002,0.762965387,1.069335185,0.705637014,1.621840593,0.868725595,DB0103910002034_,0.140727975,0.067037133,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,fenofibrate,DB01039
,21830,DB01390,10002034,42,1367,41,1476,0.657662862,1.106033005,0.697179618,1.755816826,0.790771864,DB0139010002034_,0.234745768,0.100779745,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,sodium bicarbonate,DB01390
,21834,DB00115,10005425,78,18347,19,10453,0.000439365,2.33886519,1.401592571,4.093100709,0.002772797,DB0011510005425_,5.887898622,0.84966585,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,21837,DB00264,10005425,79,29528,41,24851,0.01295831,1.621616552,1.098001837,2.426980832,0.043765253,DB0026410005425_,3.128915077,0.483423523,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,metoprolol,DB00264
,21838,DB00338,10005425,95,33579,42,22230,0.028931366,1.497416875,1.030594583,2.208532543,0.082318787,DB0033810005425_,2.497155928,0.40374154,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,omeprazole,DB00338
,21842,DB00695,10005425,55,27994,28,20500,0.120726675,1.43843404,0.896480416,2.355994413,0.242468054,DB0069510005425_,1.416885314,0.363555049,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,furosemide,DB00695
,21851,DB00126,10005483,50,10121,55,5890,0.001524475,0.5290591,0.352888211,0.791603329,0.00779512,DB0012610005483_,4.854257418,-0.636655133,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,ascorbic acid,DB00126
,21853,DB00196,10005483,24,5059,31,3254,0.012044112,0.498002796,0.279142153,0.878441583,0.041258892,DB0019610005483_,3.187888617,-0.697149587,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,fluconazole,DB00196
,21854,DB00335,10005483,50,8416,34,5431,0.823302662,0.94901431,0.600845497,1.515290212,0.906247631,DB0033510005483_,0.098442687,-0.052331401,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,atenolol,DB00335
,21855,DB00338,10005483,147,33527,131,22141,0.013927145,0.741069019,0.581204381,0.945740517,0.04637383,DB0033810005483_,3.071019985,-0.299661515,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,omeprazole,DB00338
,21857,DB00646,10005483,32,3421,26,1974,0.217869355,0.710254005,0.408731035,1.244734607,0.371056209,DB0064610005483_,0.991401722,-0.342132619,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,nystatin,DB00646
,21858,DB00864,10005483,78,6791,155,8237,0.000329328,0.610397727,0.457990233,0.808029305,0.002177978,DB0086410005483_,6.129358173,-0.493644522,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,tacrolimus,DB00864
,21860,DB01015,10005483,58,9829,167,9214,5.43842367237939e-15,0.325592035,0.236904849,0.442071015,3.30900384788177e-13,DB0101510005483_,28.73695902,-1.122110107,male,10005483,Blood creatinine increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,21861,DB01590,10005483,29,4709,44,2823,0.000130388,0.395167094,0.237840513,0.647569988,0.000999637,DB0159010005483_,6.908118699,-0.928446581,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,everolimus,DB01590
,21869,DB00264,10005802,53,29554,33,24859,0.193929166,1.350909468,0.858328352,2.154695641,0.341616334,DB0026410005802_,1.074067003,0.300778046,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,metoprolol,DB00264
,21871,DB00338,10005802,59,33615,37,22235,0.835327431,1.054767076,0.687405942,1.63729226,0.914762276,DB0033810005802_,0.089091056,0.053319962,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,omeprazole,DB00338
,21876,DB00695,10005802,84,27965,39,20489,0.017521907,1.578032034,1.066686985,2.371215011,0.055711058,DB0069510005802_,2.887576627,0.456178523,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,furosemide,DB00695
,21890,DB00264,10005839,37,29570,26,24866,0.52817437,1.196688985,0.705148589,2.058827063,0.685617231,DB0026410005839_,0.377435779,0.179558564,NA,10005839,Blood triglycerides increased,10022891,Investigations,Inv,metoprolol,DB00264
,21892,DB00338,10005839,34,33640,25,22247,0.691636447,0.899406381,0.520873674,1.572948825,0.814081634,DB0033810005839_,0.20569463,-0.10602031,NA,10005839,Blood triglycerides increased,10022891,Investigations,Inv,omeprazole,DB00338
,21928,DB00126,10008190,99,10072,58,5887,1,0.997666808,0.713114034,1.406766788,1,DB0012610008190_,0,-0.002335918,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,21929,DB00196,10008190,30,5053,24,3261,0.485007085,0.80672833,0.455047981,1.444699813,0.649146658,DB0019610008190_,0.432096612,-0.214768309,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,fluconazole,DB00196
,21932,DB00688,10008190,32,6458,35,5343,0.269531097,0.756453718,0.452742685,1.259880906,0.432094711,DB0068810008190_,0.839110477,-0.279113927,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,mycophenolate mofetil,DB00688
,21933,DB00864,10008190,23,6846,35,8357,0.430846884,0.802194819,0.452054959,1.398079804,0.59929144,DB0086410008190_,0.512007256,-0.220403784,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,tacrolimus,DB00864
,21935,DB01015,10008190,63,9824,52,9329,0.512687711,1.150483854,0.783306754,1.69621378,0.672851533,DB0101510008190_,0.396230578,0.140182597,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,21936,DB01039,10008190,20,2953,30,3021,0.202660837,0.682064171,0.366236755,1.244600895,0.352136182,DB0103910008190_,1.043737298,-0.382631533,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,fenofibrate,DB01039
,21942,DB00177,10012378,60,4740,34,2816,0.914605155,1.048396547,0.675305011,1.651615126,0.961827462,DB0017710012378_,0.038920198,0.047261899,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,valsartan,DB00177
,21943,DB00196,10012378,88,4995,12,3273,2.67012462367627e-09,4.804524369,2.611475924,9.666959026,6.81400249838162e-08,DB0019610012378_,16.50170106,1.569558051,female,10012378,Depression,10037175,Psychiatric disorders,Psych,fluconazole,DB00196
,21945,DB00641,10012378,197,13927,140,12335,0.048096962,1.246280096,0.997015855,1.56129903,0.121531233,DB0064110012378_,2.107583991,0.220163191,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,21946,DB00646,10012378,61,3392,19,1981,0.018809923,1.874818343,1.101008649,3.333516059,0.058873401,DB0064610012378_,2.832365888,0.628511771,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,nystatin,DB00646
,21947,DB00688,10012378,33,6457,30,5348,0.799914768,0.911080947,0.537917851,1.548672425,0.891818188,DB0068810012378_,0.114492992,-0.09312353,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,mycophenolate mofetil,DB00688
,21948,DB00864,10012378,24,6845,32,8360,0.789004842,0.915976368,0.515743635,1.606516497,0.88567613,DB0086410012378_,0.121403937,-0.087764714,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,tacrolimus,DB00864
,21950,DB01015,10012378,97,9790,48,9333,0.000160366,1.926427807,1.347931102,2.785960497,0.001194448,DB0101510012378_,6.730071013,0.655667411,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,sulfamethoxazole,DB01015
,21951,DB01039,10012378,66,2907,45,3006,0.034860535,1.516501186,1.018865168,2.27533334,0.095155024,DB0103910012378_,2.352247888,0.41640583,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,fenofibrate,DB01039
,21956,DB00126,10013709,379,9792,211,5734,0.572373845,1.051825352,0.883597494,1.25464405,0.722394527,DB0012610013709_,0.325183854,0.050527085,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,21957,DB00598,10013709,75,1513,29,999,0.018038177,1.707284043,1.089415793,2.740249099,0.056939292,DB0059810013709_,2.865769623,0.534903829,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,labetalol,DB00598
,21958,DB00646,10013709,108,3345,62,1938,1,1.00922745,0.727875821,1.40970105,1,DB0064610013709_,0,0.009185137,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,21959,DB00877,10013709,45,1063,39,1392,0.073038842,1.510688689,0.954235599,2.400962574,0.166578312,DB0087710013709_,1.79228974,0.412565632,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sirolimus,DB00877
,21960,DB01015,10013709,229,9658,256,9125,0.07269294,0.845173085,0.702391727,1.016514343,0.166013635,DB0101510013709_,1.795685353,-0.168213838,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,21961,DB01039,10013709,126,2847,134,2917,0.799896396,0.963414201,0.745125355,1.245142113,0.891818188,DB0103910013709_,0.114492992,-0.037271845,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,21962,DB01390,10013709,101,1308,113,1404,0.776788802,0.959408135,0.718319611,1.280119903,0.878377873,DB0139010013709_,0.129678399,-0.04143871,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sodium bicarbonate,DB01390
,21963,DB01590,10013709,160,4578,75,2792,0.06504357,1.301008876,0.978681276,1.742498174,0.152512955,DB0159010013709_,1.880505734,0.263140022,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,21984,DB00177,10016173,149,4651,55,2795,0.001989398,1.627919448,1.182714269,2.26858443,0.009682681,DB0017710016173_,4.637416427,0.487302787,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,valsartan,DB00177
,21985,DB00196,10016173,109,4974,48,3237,0.025774213,1.477755582,1.039820018,2.127229233,0.075195646,DB0019610016173_,2.587661944,0.390524438,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,fluconazole,DB00196
,21986,DB00598,10016173,45,1543,21,1007,0.250608871,1.39830865,0.810199046,2.486884982,0.410433608,DB0059810016173_,0.890541098,0.335263399,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,labetalol,DB00598
,21987,DB00646,10016173,100,3353,50,1950,0.439523576,1.163138516,0.816192478,1.675631067,0.607910896,DB0064610016173_,0.497726961,0.151121969,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,nystatin,DB00646
,21988,DB00688,10016173,76,6414,27,5351,8.80722106135725e-05,2.348092137,1.493267943,3.796318795,0.000716157,DB0068810016173_,7.241610902,0.853603142,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,mycophenolate mofetil,DB00688
,21989,DB00864,10016173,55,6814,45,8347,0.054838273,1.497137076,0.989869272,2.274974798,0.134052488,DB0086410016173_,2.009523852,0.403554668,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,tacrolimus,DB00864
,21991,DB01015,10016173,177,9710,145,9236,0.196079156,1.161091051,0.925137721,1.459100949,0.344353619,DB0101510016173_,1.066086188,0.149360124,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sulfamethoxazole,DB01015
,21992,DB01039,10016173,100,2873,85,2966,0.204557554,1.214511806,0.896083628,1.649178706,0.35457632,DB0103910016173_,1.036831668,0.19434219,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,fenofibrate,DB01039
,21994,DB01590,10016173,45,4693,25,2842,0.804780017,1.090049317,0.652665878,1.859216312,0.894427482,DB0159010016173_,0.11157145,0.08622294,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,everolimus,DB01590
,21998,DB00115,10016970,50,18375,10,10462,0.001131776,2.846708017,1.426052293,6.298800088,0.006100135,DB0011510016970_,5.099444355,1.046163245,female,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,22002,DB00264,10016970,48,29559,9,24883,3.0671827137227e-06,4.489467977,2.178231285,10.41103059,3.86485607047944e-05,DB0026410016970_,10.16100102,1.501734204,female,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,22004,DB00338,10016970,78,33596,6,22266,1.3795072517255e-11,8.616581619,3.783897214,24.19660661,5.13602664470323e-10,DB0033810016970_,21.38957118,2.153688442,female,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,22009,DB00695,10016970,54,27995,17,20511,0.001627921,2.327232557,1.328104838,4.283342682,0.008212243,DB0069510016970_,4.802129164,0.844679818,NA,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,22019,DB00177,10017955,53,4747,57,2793,0.00195855,0.547152113,0.368058784,0.812153162,0.009574205,DB0017710017955_,4.648682809,-0.603028429,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,valsartan,DB00177
,22024,DB01039,10017955,30,2943,50,3001,0.042093749,0.6118771,0.374515561,0.984313865,0.10988521,DB0103910017955_,2.208319004,-0.491223834,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,fenofibrate,DB01039
,22034,DB00264,10019641,32,29575,22,24870,0.496977475,1.223140644,0.688772181,2.210092402,0.659117661,DB0026410019641_,0.416853216,0.20142185,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,metoprolol,DB00264
,22036,DB00338,10019641,42,33632,40,22232,0.11353598,0.694109965,0.439146094,1.0985433,0.231430262,DB0033810019641_,1.463476695,-0.36512488,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,omeprazole,DB00338
,22041,DB00695,10019641,83,27966,88,20440,0.016111334,0.689376826,0.504229748,0.941774765,0.052105371,DB0069510019641_,2.954487249,-0.371967241,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,furosemide,DB00695
,22071,DB00177,10020772,121,4679,58,2792,0.184111867,1.244791983,0.899548914,1.739482895,0.329064049,DB0017710020772_,1.11150287,0.218968434,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,valsartan,DB00177
,22072,DB00196,10020772,60,5023,35,3250,0.673386761,1.109191544,0.717370578,1.738488108,0.801900054,DB0019610020772_,0.2207713,0.103631411,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,fluconazole,DB00196
,22073,DB00335,10020772,165,8301,110,5355,0.803145563,0.967636557,0.753687315,1.246350759,0.893441443,DB0033510020772_,0.112674484,-0.03289872,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,atenolol,DB00335
,22074,DB00598,10020772,65,1523,41,987,0.91951744,1.027408325,0.678426708,1.571477193,0.964382416,DB0059810020772_,0.036267366,0.027039442,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,labetalol,DB00598
,22075,DB00646,10020772,72,3381,36,1964,0.482519995,1.161786029,0.765077491,1.792009809,0.646879252,DB0064610020772_,0.435595629,0.149958501,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,nystatin,DB00646
,22076,DB00688,10020772,107,6383,65,5313,0.05346245,1.370166435,0.995153785,1.898920422,0.131486363,DB0068810020772_,2.028852137,0.314932218,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,mycophenolate mofetil,DB00688
,22077,DB00695,10020772,453,27596,239,20289,3.26168399223515e-05,1.393514395,1.187490964,1.638567775,0.000305481,DB0069510020772_,8.093621562,0.331828898,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,furosemide,DB00695
,22078,DB00864,10020772,109,6760,126,8266,0.692005372,1.05776775,0.809249034,1.380885966,0.814300902,DB0086410020772_,0.205425323,0.056160791,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,tacrolimus,DB00864
,22080,DB01015,10020772,109,9778,90,9291,0.354204073,1.150781805,0.861142194,1.541050068,0.524068717,DB0101510020772_,0.646132463,0.140441542,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,sulfamethoxazole,DB01015
,22081,DB01039,10020772,56,2917,37,3014,0.036702713,1.563717344,1.010746353,2.444759057,0.098968431,DB0103910020772_,2.312954356,0.447065899,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,fenofibrate,DB01039
,22106,DB00115,10024855,183,18242,83,10389,0.095541521,1.255687692,0.962477835,1.64973118,0.204063616,DB0011510024855_,1.589323492,0.227683384,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,22107,DB00126,10024855,74,10097,34,5911,0.271433057,1.274148829,0.836890841,1.97542513,0.434232606,DB0012610024855_,0.834174931,0.242278371,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,22109,DB00264,10024855,198,29409,167,24725,1,0.996792438,0.806584628,1.233052827,1,DB0026410024855_,0,-0.003212717,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,22110,DB00335,10024855,71,8395,40,5425,0.558350262,1.147060743,0.76662889,1.737509464,0.711316449,DB0033510024855_,0.340637872,0.137202795,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,22111,DB00338,10024855,244,33430,141,22131,0.21007105,1.14564038,0.926590948,1.420775924,0.36125074,DB0033810024855_,1.018182991,0.135963765,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,22113,DB00641,10024855,113,14011,88,12387,0.394977261,1.135244516,0.850601953,1.519263758,0.564836501,DB0064110024855_,0.571218969,0.12684806,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,22116,DB00695,10024855,268,27781,156,20372,0.02307024,1.259777124,1.029396331,1.54601324,0.06907407,DB0069510024855_,2.672575869,0.230934819,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,22119,DB01015,10024855,46,9841,38,9343,0.5848114,1.149259139,0.73083396,1.816855874,0.732512158,DB0101510024855_,0.31127534,0.139117508,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,22147,DB00115,10028810,334,18091,127,10345,7.36145093440614e-05,1.503850855,1.220484643,1.862389664,0.000612813,DB0011510028810_,7.397450555,0.408029055,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,22148,DB00126,10028810,232,9939,94,5851,0.002101406,1.452907206,1.135881464,1.870877922,0.010133662,DB0012610028810_,4.591892573,0.373566519,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,22149,DB00177,10028810,68,4732,27,2823,0.087038236,1.502413119,0.946427298,2.447554185,0.190119254,DB0017710028810_,1.660103753,0.407072562,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,valsartan,DB00177
,22150,DB00196,10028810,60,5023,8,3277,6.35089475682535e-07,4.892298637,2.326036959,11.86358824,9.5691182965408e-06,DB0019610028810_,11.55696949,1.587662262,female,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,fluconazole,DB00196
,22151,DB00264,10028810,427,29180,195,24697,2.97494651965778e-13,1.853301985,1.559479029,2.208770563,1.43743509686038e-11,DB0026410028810_,24.96557568,0.616968905,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,metoprolol,DB00264
,22152,DB00335,10028810,102,8364,54,5411,0.249068003,1.221955,0.868589161,1.735764043,0.408482715,DB0033510028810_,0.89530568,0.200452036,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,atenolol,DB00335
,22153,DB00338,10028810,505,33169,239,22033,1.40405738443677e-05,1.403563002,1.199831603,1.645590441,0.000146422,DB0033810028810_,8.829018148,0.339014005,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,omeprazole,DB00338
,22155,DB00641,10028810,208,13916,93,12382,1.87746935467551e-08,1.989961055,1.549056988,2.572487102,3.95585426754675e-07,DB0064110028810_,14.74289908,0.688115068,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,simvastatin,DB00641
,22156,DB00646,10028810,56,3397,19,1981,0.04061151,1.718634261,1.002251313,3.07240658,0.106870256,DB0064610028810_,2.23613974,0.541529941,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,nystatin,DB00646
,22158,DB00695,10028810,472,27577,152,20376,7.47480541752581e-21,2.294342476,1.90525223,2.775580528,8.59847966738144e-19,DB0069510028810_,41.59753136,0.830446299,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,furosemide,DB00695
,22161,DB01015,10028810,106,9781,68,9313,0.011796461,1.484200886,1.082810073,2.046139915,0.040616662,DB0101510028810_,3.203576915,0.394876503,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,22162,DB01039,10028810,52,2921,21,3030,0.000212042,2.568257915,1.515910304,4.500540944,0.001512696,DB0103910028810_,6.493861468,0.943227815,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,fenofibrate,DB01039
,22164,DB01590,10028810,53,4685,32,2835,1,1.002234241,0.632658023,1.610592998,1,DB0159010028810_,0,0.002231749,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,everolimus,DB01590
,22168,DB00177,10035528,33,4767,33,2817,0.039997113,0.591006991,0.352679015,0.990298918,0.105676647,DB0017710035528_,2.247371351,-0.525927433,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,valsartan,DB00177
,22169,DB00196,10035528,75,5008,68,3217,0.046676269,0.708545949,0.501844362,1.001841114,0.118842375,DB0019610035528_,2.129957241,-0.344540369,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,fluconazole,DB00196
,22170,DB00335,10035528,67,8399,63,5402,0.037508395,0.684045986,0.476744445,0.982393335,0.100602874,DB0033510035528_,2.296574454,-0.379730133,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,atenolol,DB00335
,22172,DB00646,10035528,53,3400,30,1970,1,1.02362401,0.63973769,1.665505031,1,DB0064610035528_,0,0.023349282,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,nystatin,DB00646
,22174,DB00864,10035528,36,6833,29,8363,0.104308868,1.519279678,0.904746534,2.571718497,0.217470442,DB0086410035528_,1.525692335,0.418236327,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,tacrolimus,DB00864
,22176,DB01015,10035528,129,9758,182,9199,0.000476005,0.668205796,0.528058917,0.84350623,0.00296558,DB0101510035528_,5.820682684,-0.403159075,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,22177,DB01039,10035528,31,2942,31,3020,1,1.026513692,0.601801237,1.750997246,1,DB0103910035528_,0,0.026168296,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,fenofibrate,DB01039
,22179,DB01590,10035528,44,4694,54,2813,0.000484855,0.488337447,0.319441586,0.743034598,0.003014292,DB0159010035528_,5.804390337,-0.716748621,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,everolimus,DB01590
,22182,DB00012,10037844,53,1593,43,1270,1,0.982643951,0.640071599,1.515918316,1,DB0001210037844_,0,-0.017508431,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,darbepoetin alfa,DB00012
,22183,DB00115,10037844,607,17818,300,10172,0.045437354,1.155110737,1.001986198,1.333752207,0.116405541,DB0011510037844_,2.150675138,0.144196215,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,22184,DB00126,10037844,326,9845,162,5783,0.086579184,1.182089919,0.973247639,1.440148669,0.189336816,DB0012610037844_,1.664227754,0.167283989,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ascorbic acid,DB00126
,22185,DB00177,10037844,152,4648,76,2774,0.237132562,1.193564227,0.896606583,1.600124334,0.394477521,DB0017710037844_,0.930193122,0.17694398,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,valsartan,DB00177
,22186,DB00196,10037844,161,4922,71,3214,0.006303779,1.480648824,1.108943411,1.993515775,0.024638717,DB0019610037844_,3.703436197,0.392480387,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,fluconazole,DB00196
,22188,DB00646,10037844,116,3337,57,1943,0.336133884,1.184953753,0.851199918,1.665351904,0.505257999,DB0064610037844_,0.682686091,0.169703747,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,nystatin,DB00646
,22189,DB00688,10037844,113,6377,71,5307,0.073041595,1.324469638,0.973368694,1.812406944,0.166578312,DB0068810037844_,1.79228974,0.281012106,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,mycophenolate mofetil,DB00688
,22190,DB00864,10037844,121,6748,103,8289,0.006760352,1.442978199,1.09805255,1.899140217,0.026064664,DB0086410037844_,3.647174736,0.366709172,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,tacrolimus,DB00864
,22191,DB01015,10037844,413,9474,406,8975,0.617070014,0.963653223,0.835654612,1.111327041,0.758159502,DB0101510037844_,0.27686149,-0.037023776,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,22192,DB01039,10037844,79,2894,66,2985,0.239126205,1.234561711,0.875278807,1.74605659,0.396870895,DB0103910037844_,0.924144252,0.210716017,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,fenofibrate,DB01039
,22194,DB01590,10037844,256,4482,153,2714,0.916556469,1.013178468,0.821186902,1.253335563,0.962743238,DB0159010037844_,0.03796853,0.013092387,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,everolimus,DB01590
,22197,DB00115,10038435,133,18292,92,10380,0.144493054,0.820367832,0.623462781,1.083354062,0.276318655,DB0011510038435_,1.286200532,-0.198002464,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,cyanocobalamin,DB00115
,22198,DB00126,10038435,73,10098,66,5879,0.010406761,0.643988891,0.454500775,0.913881766,0.036734907,DB0012610038435_,3.304027832,-0.440073803,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,ascorbic acid,DB00126
,22199,DB00338,10038435,392,33282,348,21924,7.01668998995572e-05,0.74204002,0.639995659,0.860659541,0.000587949,DB0033810038435_,7.438871197,-0.298352102,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,22200,DB00598,10038435,30,1558,26,1002,0.271899998,0.742176758,0.421446282,1.314884253,0.434752203,DB0059810038435_,0.832979059,-0.298167846,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,labetalol,DB00598
,22201,DB00641,10038435,122,14002,135,12340,0.078468315,0.796446305,0.617572611,1.026327128,0.1758121,DB0064110038435_,1.738339469,-0.227595566,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,simvastatin,DB00641
,22202,DB00688,10038435,60,6430,62,5316,0.235108107,0.800099084,0.55045585,1.162234551,0.392120343,DB0068810038435_,0.93618649,-0.223019704,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,mycophenolate mofetil,DB00688
,22203,DB00695,10038435,397,27652,355,20173,0.005893906,0.815850458,0.704387634,0.945216767,0.02334383,DB0069510038435_,3.757422582,-0.203524203,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,22204,DB00864,10038435,105,6764,145,8247,0.369604756,0.882925277,0.678687659,1.145357739,0.539238721,DB0086410038435_,0.617596909,-0.124514706,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,tacrolimus,DB00864
,22206,DB01039,10038435,25,2948,41,3010,0.064030596,0.622631524,0.36185867,1.051683952,0.150695635,DB0103910038435_,1.892493136,-0.473800389,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,fenofibrate,DB01039
,22207,DB01390,10038435,46,1363,61,1456,0.280436181,0.805612389,0.533149089,1.210118633,0.444292992,DB0139010038435_,0.811271043,-0.216152559,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,sodium bicarbonate,DB01390
,22208,DB01590,10038435,35,4703,29,2838,0.243440061,0.728345639,0.431447684,1.238150281,0.401786422,DB0159010038435_,0.911834619,-0.316979564,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,everolimus,DB01590
,22276,DB00564,10022437,44,2560,23,1440,0.897964685,1.076075392,0.632896794,1.874969676,0.956338178,DB0056410022437_,0.044643686,0.073320526,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,carbamazepine,DB00564
,22277,DB00564,10041349,31,2573,24,1439,0.258159376,0.722474514,0.408626624,1.291768173,0.419078508,DB0056410041349_,0.869697008,-0.325073135,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,carbamazepine,DB00564
,22278,DB00564,10047899,48,2556,14,1449,0.032030323,1.943376812,1.049476394,3.830567455,0.089166786,DB0056410047899_,2.417246666,0.664427085,NA,10047899,Weight increased,10022891,Investigations,Inv,carbamazepine,DB00564
,22286,DB00555,10026749,46,7001,26,3460,0.6156671,0.874398667,0.528282189,1.476194869,0.757016036,DB0055510026749_,0.278370842,-0.134218867,NA,10026749,Mania,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,22288,DB00215,10042458,99,11004,53,5223,0.486091748,0.886614506,0.627757857,1.264375321,0.649960453,DB0021510042458_,0.430843759,-0.120344995,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,22291,DB06228,10038063,328,15584,427,15649,0.000462814,0.771362319,0.664752539,0.89441707,0.002895753,DB0622810038063_,5.844510257,-0.259597082,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,22292,DB00158,10007554,31,16784,27,8077,0.025042319,0.552510932,0.318919003,0.962901801,0.073541965,DB0015810007554_,2.609899087,-0.59328206,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,folic acid,DB00158
,22293,DB00264,10007554,146,29461,175,24717,0.001615613,0.699954944,0.557601103,0.877544986,0.008162688,DB0026410007554_,4.808181768,-0.356739312,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,metoprolol,DB00264
,22294,DB00381,10007554,103,29257,110,22777,0.022342759,0.728984956,0.551417431,0.963110538,0.067398798,DB0038110007554_,2.697128091,-0.316102184,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,amlodipine,DB00381
,22296,DB01275,10007554,27,3952,37,3312,0.058406112,0.611603879,0.357311548,1.03447862,0.140515735,DB0127510007554_,1.962435804,-0.491670462,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,hydralazine,DB01275
,22298,DB00381,10010264,504,28856,216,22671,2.05513750549574e-14,1.833170087,1.558433813,2.162223217,1.15796976059926e-12,DB0038110010264_,27.48435285,0.606046756,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,22299,DB00443,10010264,38,2108,16,1174,0.392424893,1.322593011,0.716462481,2.552349921,0.562333769,DB0044310010264_,0.575659711,0.279594212,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,betamethasone,DB00443
,22300,DB01275,10010264,61,3918,34,3315,0.061541485,1.517905877,0.979257125,2.388088388,0.14629147,DB0127510010264_,1.922154277,0.417331672,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,22301,DB01373,10010264,338,22382,68,7313,0.000191482,1.623984715,1.246494606,2.142621247,0.001388828,DB0137310010264_,6.579294859,0.48488283,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,22318,DB00563,10006784,112,46534,26,15322,0.114457998,1.418338107,0.918742327,2.265930549,0.232840219,DB0056310006784_,1.457402815,0.349485839,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,22320,DB01234,10013700,230,31395,117,32771,9.90720043139313e-11,2.051935001,1.63454216,2.587491674,3.23290829719638e-09,DB0123410013700_,19.5498837,0.718783251,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,dexamethasone,DB01234
,22322,DB01088,10002034,45,1384,10,427,0.420692405,1.38812012,0.682292532,3.116131715,0.589676035,DB0108810002034_,0.528181986,0.3279504,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,iloprost,DB01088
,22323,DB09140,10002034,162,3579,55,1743,0.021898452,1.434370874,1.044151683,1.995777755,0.066389943,DB0914010002034_,2.712209692,0.360726337,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,oxygen,DB09140
,22324,DB01088,10003549,72,1357,22,415,1,1.000870451,0.60470173,1.716829013,1,DB0108810003549_,0,0.000870073,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,iloprost,DB01088
,22325,DB09140,10003549,247,3494,112,1686,0.641091731,1.064169128,0.841092932,1.352944864,0.777943746,DB0914010003549_,0.251101063,0.062194333,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,22329,DB09140,10007559,132,3609,64,1734,0.938265927,0.990958968,0.725472374,1.365221771,0.978081297,DB0914010007559_,0.022162487,-0.00908215,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,oxygen,DB09140
,22330,DB01088,10013573,104,1325,36,401,0.533504819,0.874380091,0.582543292,1.337539054,0.69022372,DB0108810013573_,0.370739503,-0.134240111,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,iloprost,DB01088
,22331,DB09140,10013573,374,3367,109,1689,7.33955190693419e-07,1.721045265,1.375087521,2.167837729,1.08870718371137e-05,DB0914010013573_,11.42793454,0.542931819,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,oxygen,DB09140
,22332,DB01088,10013968,348,1081,88,349,0.070695362,1.276532658,0.975755921,1.681492874,0.162521975,DB0108810013968_,1.816942054,0.244147541,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iloprost,DB01088
,22333,DB01088,10016256,137,1292,32,405,0.154431758,1.341797705,0.891264095,2.071736451,0.290038852,DB0108810016256_,1.237740394,0.294010286,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,iloprost,DB01088
,22337,DB01088,10028735,45,1384,8,429,0.187220871,1.74305994,0.80504105,4.315476359,0.333035603,DB0108810028735_,1.099505879,0.555642155,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iloprost,DB01088
,22338,DB09140,10028735,196,3545,52,1746,5.27212516296215e-05,1.856253481,1.353007287,2.585299079,0.000462311,DB0914010028735_,7.679272101,0.618560199,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,22339,DB00203,10033318,526,13352,217,8721,9.02129979030014e-09,1.583204863,1.345798787,1.867451121,2.04940651231721e-07,DB0020310033318_,15.40054541,0.459451187,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,sildenafil,DB00203
,22340,DB01088,10033318,52,1377,26,411,0.040319046,0.59713564,0.360881607,1.00966413,0.10626553,DB0108810033318_,2.241814316,-0.515610989,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,iloprost,DB01088
,22341,DB09140,10033318,347,3394,136,1662,0.036958176,1.249331698,1.012515473,1.548281891,0.099492592,DB0914010033318_,2.30767209,0.222608767,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,oxygen,DB09140
,22342,DB00203,10037400,580,13298,248,8690,2.13871251847213e-08,1.528275397,1.311508058,1.78498213,4.45805381031245e-07,DB0020310037400_,14.62338335,0.424139908,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,22343,DB01088,10037400,50,1379,16,421,0.882526579,0.954063459,0.527676532,1.814486136,0.950900231,DB0108810037400_,0.050346132,-0.047025091,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iloprost,DB01088
,22344,DB09140,10037400,203,3538,62,1736,0.001207631,1.606430675,1.195673533,2.183809454,0.006436698,DB0914010037400_,5.045739674,0.474014746,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,22348,DB00203,10055798,136,13742,68,8870,0.097302269,1.29091259,0.956714743,1.755747252,0.206816005,DB0020310055798_,1.575925745,0.255349402,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,sildenafil,DB00203
,22350,DB09140,10055798,34,3707,19,1779,0.658526325,0.858807491,0.474612371,1.598644758,0.79150233,DB0914010055798_,0.233822456,-0.15221049,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,oxygen,DB09140
,22354,DB01164,10021789,50,6474,60,7876,1,1.013800134,0.681267263,1.502928296,1,DB0116410021789_,0,0.013705779,NA,10021789,Infection,10021881,Infections and infestations,Infec,calcium chloride,DB01164
,22357,DB01261,10033647,43,3738,54,3249,0.081315204,0.692168033,0.451306964,1.055803844,0.180566878,DB0126110033647_,1.711654054,-0.367926531,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,sitagliptin,DB01261
,22359,DB00169,10000060,316,38375,108,18067,0.003988372,1.37755414,1.10293234,1.731377596,0.017043468,DB0016910000060_,4.071988273,0.320309564,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,22360,DB00264,10000060,208,29399,144,24748,0.076453737,1.215924239,0.97778854,1.515449992,0.172260114,DB0026410000060_,1.758749656,0.195504478,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,22361,DB00343,10000060,89,8647,31,5064,0.013150432,1.68128448,1.104021474,2.622484024,0.04430107,DB0034310000060_,3.116746448,0.519558073,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,22363,DB00761,10000060,173,15134,88,8537,0.475885701,1.108967048,0.851834144,1.452339898,0.64142018,DB0076110000060_,0.44407053,0.103428995,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,22364,DB00787,10000060,93,16907,80,17168,0.286655672,1.180438841,0.865325516,1.613324771,0.451412057,DB0078710000060_,0.795374706,0.165886269,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,22367,DB01060,10000060,56,8531,33,5048,1,1.004137933,0.640771674,1.596315893,1,DB0106010000060_,0,0.004129395,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,22368,DB01377,10000060,41,3755,17,2653,0.080695274,1.703834591,0.944464712,3.206049743,0.179508741,DB0137710000060_,1.717531373,0.532881353,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,magnesium oxide,DB01377
,22370,DB00343,10008531,69,8667,33,5062,0.40987905,1.221229896,0.794146768,1.912159355,0.57933863,DB0034310008531_,0.54586812,0.199858462,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,22372,DB00761,10008531,155,15152,69,8556,0.107872454,1.268493562,0.947979027,1.712108233,0.222873786,DB0076110008531_,1.501149652,0.237830024,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,22373,DB00787,10008531,101,16899,112,17136,0.536558911,0.914451909,0.691163931,1.208543115,0.692857016,DB0078710008531_,0.366931628,-0.0894304,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,22375,DB00987,10008531,40,2064,62,2866,0.613629617,0.895840943,0.584013493,1.36058866,0.755344767,DB0098710008531_,0.280580989,-0.1099924,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,cytarabine,DB00987
,22376,DB01060,10008531,72,8515,40,5041,0.769508691,1.065627055,0.713017505,1.61278889,0.873773071,DB0106010008531_,0.134934581,0.06356341,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,22380,DB00787,10013573,411,16589,339,16909,0.004447975,1.235765911,1.065879171,1.433444347,0.01860223,DB0078710013573_,3.984473833,0.211690948,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,22381,DB00860,10013573,45,1838,17,1479,0.006672232,2.129552929,1.189339375,3.986427013,0.025787327,DB0086010013573_,3.657872124,0.755912065,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,prednisolone,DB00860
,22382,DB00987,10013573,26,2078,42,2886,0.621044282,0.859798689,0.504349759,1.440583865,0.761476336,DB0098710013573_,0.272496182,-0.151057,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,cytarabine,DB00987
,22383,DB01060,10013573,219,8368,96,4985,0.013160918,1.358960919,1.061402327,1.750599677,0.044327876,DB0106010013573_,3.116141552,0.306720378,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,amoxicillin,DB01060
,22384,DB01377,10013573,123,3673,90,2580,0.777522605,0.959958478,0.721947944,1.280547172,0.878740499,DB0137710013573_,0.129265648,-0.040865248,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,magnesium oxide,DB01377
,22385,DB00009,10016256,48,1303,37,1514,0.076905743,1.507144087,0.954561533,2.396407486,0.173026402,DB0000910016256_,1.754311084,0.410216527,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,alteplase,DB00009
,22387,DB00860,10016256,96,1787,62,1434,0.218473718,1.242442241,0.886291694,1.752371167,0.371678893,DB0086010016256_,0.989724988,0.217078992,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,prednisolone,DB00860
,22388,DB01060,10016256,471,8116,265,4816,0.505413834,1.05467877,0.901418881,1.235947408,0.666355811,DB0106010016256_,0.4059315,0.053236237,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,22389,DB00169,10016288,142,38549,133,18042,1.77301300720837e-08,0.499688976,0.391389686,0.638303757,3.75987469902962e-07,DB0016910016288_,14.79371002,-0.693769422,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,22390,DB00264,10016288,83,29524,147,24745,2.76404899952696e-08,0.473233466,0.356914424,0.6238987,5.61663419559284e-07,DB0026410016288_,14.39236306,-0.748166427,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,metoprolol,DB00264
,22392,DB00761,10016288,130,15177,117,8508,0.000240709,0.622856342,0.480757544,0.807781627,0.001681158,DB0076110016288_,6.38827233,-0.473439377,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,potassium chloride,DB00761
,22393,DB00860,10016288,33,1850,29,1467,0.700476352,0.902376924,0.528500736,1.548333383,0.819933687,DB0086010016288_,0.198531811,-0.102722971,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,prednisolone,DB00860
,22394,DB01060,10016288,40,8547,58,5023,1.23222616553441e-05,0.405330125,0.263551176,0.617929764,0.000130362,DB0106010016288_,8.945197567,-0.903053421,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,amoxicillin,DB01060
,22395,DB01377,10016288,31,3765,49,2621,0.000347094,0.440473682,0.27072783,0.706865873,0.002278848,DB0137710016288_,6.08408538,-0.819904582,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,magnesium oxide,DB01377
,22397,DB00169,10016326,65,38626,22,18153,0.206058788,1.388568019,0.844455833,2.366105527,0.356520224,DB0016910016326_,1.031364312,0.328273014,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,22406,DB00169,10016825,287,38404,92,18083,0.001094426,1.468876697,1.156778183,1.879904632,0.005931335,DB0016910016825_,5.127505981,0.384497957,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,22407,DB00264,10016825,155,29452,81,24811,0.000493766,1.612023176,1.223687455,2.137149325,0.003061002,DB0026410016825_,5.78901295,0.477490021,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,22408,DB00343,10016825,88,8648,33,5062,0.029374849,1.56085279,1.033587459,2.408572915,0.083323574,DB0034310016825_,2.485023765,0.445232332,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,diltiazem,DB00343
,22410,DB00761,10016825,116,15191,38,8587,0.003095564,1.725520665,1.185696223,2.561688651,0.013878032,DB0076110016825_,4.27744812,0.54552884,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,potassium chloride,DB00761
,22411,DB00787,10016825,59,16941,33,17215,0.006360251,1.816752576,1.166386805,2.873840541,0.024809555,DB0078710016825_,3.69652642,0.597050609,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,acyclovir,DB00787
,22416,DB00009,10028813,80,1271,82,1469,0.466723024,1.127545066,0.810343401,1.568424902,0.633373673,DB0000910028813_,0.45669471,0.120042761,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,alteplase,DB00009
,22417,DB00343,10028813,581,8155,166,4929,1.32158313180777e-18,2.11533926,1.770504852,2.538399283,1.20827174328929e-16,DB0034310028813_,36.65217046,0.749215206,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,22418,DB00694,10028813,31,603,30,741,0.361285001,1.2695926,0.734171781,2.19820281,0.5311618,DB0069410028813_,0.632688596,0.238696062,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,daunorubicin,DB00694
,22420,DB00343,10042772,110,8626,79,5016,0.171563979,0.80970426,0.599604112,1.097609465,0.312859664,DB0034310042772_,1.162000546,-0.211086209,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,22422,DB00787,10042772,116,16884,105,17143,0.418253931,1.121704596,0.853187855,1.476201689,0.587244516,DB0078710042772_,0.532313994,0.114849489,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,22425,DB01060,10042772,36,8551,29,5052,0.246711515,0.73345399,0.436691434,1.24173005,0.405776412,DB0106010042772_,0.901952981,-0.30999041,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,amoxicillin,DB01060
,22426,DB01377,10042772,35,3761,26,2644,0.896218593,0.94637697,0.552081053,1.641386638,0.956301489,DB0137710042772_,0.044682051,-0.055114301,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,magnesium oxide,DB01377
,22443,DB00650,10029354,37,2094,93,1921,9.09298758941429e-08,0.365064423,0.241133006,0.542767635,1.65920984927285e-06,DB0065010029354_,13.30916906,-1.00768144,male,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,leucovorin,DB00650
,22449,DB00175,10002034,147,7984,101,6005,0.517715642,1.094703122,0.841977687,1.427872314,0.677263695,DB0017510002034_,0.389694576,0.090483205,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,pravastatin,DB00175
,22450,DB00928,10002034,20,815,55,1231,0.022231083,0.549392263,0.309414103,0.93967258,0.067150541,DB0092810002034_,2.700818304,-0.598942589,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,azacitidine,DB00928
,22451,DB00188,10021143,25,7861,33,8795,0.598915546,0.84759558,0.482751374,1.47088495,0.7436826,DB0018810021143_,0.296140948,-0.165351667,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bortezomib,DB00188
,22452,DB00480,10021143,77,67351,70,67592,0.564370785,1.103926984,0.788100847,1.548566287,0.716209347,DB0048010021143_,0.333782771,0.098873808,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,22453,DB01234,10021143,128,31497,189,32699,0.002307761,0.703100602,0.5570053,0.885105393,0.01092887,DB0123410021143_,4.516347362,-0.352255293,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,22459,DB00982,10013709,85,3279,59,2042,0.543950036,0.89720345,0.632993135,1.278892848,0.699052789,DB0098210013709_,0.358029019,-0.108472631,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,isotretinoin,DB00982
,22479,DB00169,10012218,44,38647,40,18135,0.003166288,0.516158059,0.328548449,0.813099164,0.014140893,DB0016910012218_,4.258684483,-0.661342245,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,22480,DB00186,10012218,136,16765,160,9848,3.29994192520113e-09,0.499304379,0.393757997,0.632423502,8.25692275144328e-08,DB0018610012218_,16.30962877,-0.694539391,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,22482,DB00213,10012218,36,18859,41,13380,0.048303432,0.622978073,0.386603663,0.999816895,0.121900602,DB0021310012218_,2.104549306,-0.473243957,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,22486,DB00512,10012218,19,4718,33,5065,0.096727686,0.618135647,0.331586775,1.121171431,0.205861077,DB0051210012218_,1.580553719,-0.481047352,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,vancomycin,DB00512
,22501,DB00186,10016173,503,16398,222,9786,0.000181888,1.35214915,1.149937865,1.593928929,0.001331175,DB0018610016173_,6.621693148,0.30169529,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,22502,DB00207,10016173,144,8936,54,5401,0.002411068,1.611707142,1.16879963,2.250719999,0.011331112,DB0020710016173_,4.480203023,0.477293954,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,azithromycin,DB00207
,22503,DB00213,10016173,614,18281,347,13074,0.000542526,1.265447316,1.105369862,1.450526066,0.003301379,DB0021310016173_,5.713414961,0.235425669,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,22505,DB00433,10016173,167,7489,135,5885,0.814865206,0.972079271,0.768076156,1.232155162,0.900608932,DB0043310016173_,0.104684153,-0.028317923,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,prochlorperazine,DB00433
,22508,DB00706,10016173,52,1023,641,15284,0.201629224,1.211995583,0.889131351,1.622110716,0.351039852,DB0070610016173_,1.046855525,0.192268243,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,tamsulosin,DB00706
,22510,DB00860,10016173,33,1850,24,1472,0.788989904,1.094056072,0.624185815,1.943773532,0.88567613,DB0086010016173_,0.121403937,0.089891956,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisolone,DB00860
,22511,DB00987,10016173,16,2088,38,2890,0.072244137,0.58283956,0.302544988,1.073889569,0.165203979,DB0098710016173_,1.800574332,-0.539843327,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,cytarabine,DB00987
,22513,DB01275,10016173,105,3874,69,3280,0.106538199,1.288365287,0.938305447,1.778408939,0.220918,DB0127510016173_,1.509963686,0.253374195,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,hydralazine,DB01275
,22515,DB00169,10021097,429,38262,333,17842,1.03081723151502e-11,0.600741586,0.518819235,0.696100356,3.92966365922732e-10,DB0016910021097_,21.65729709,-0.509590411,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,22517,DB00335,10021097,191,8275,140,5325,0.254757512,0.877935197,0.700229985,1.102896597,0.415502987,DB0033510021097_,0.878265475,-0.130182496,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,atenolol,DB00335
,22518,DB00512,10021097,175,4562,207,4891,0.374673025,0.906401635,0.733795656,1.118568439,0.544536523,DB0051210021097_,0.607820262,-0.098272765,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,vancomycin,DB00512
,22519,DB00646,10021097,75,3378,58,1942,0.101087153,0.743462603,0.518165635,1.071249738,0.212447094,DB0064610021097_,1.549062289,-0.296436812,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,nystatin,DB00646
,22521,DB00706,10021097,15,1060,388,15537,0.028994377,0.566699512,0.312913804,0.950852777,0.082466828,DB0070610021097_,2.495359149,-0.567926076,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,tamsulosin,DB00706
,22522,DB00787,10021097,210,16790,295,16953,0.000275727,0.71878516,0.598520742,0.862005717,0.001883933,DB0078710021097_,6.274393841,-0.33019277,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,acyclovir,DB00787
,22523,DB00836,10021097,159,5376,127,3948,0.504267819,0.919423081,0.720794737,1.174669701,0.665378862,DB0083610021097_,0.407398684,-0.084008891,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,loperamide,DB00836
,22524,DB01275,10021097,94,3885,134,3215,6.3312137404277e-05,0.580566162,0.439273815,0.764742724,0.000538999,DB0127510021097_,7.525796771,-0.543751509,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,hydralazine,DB01275
,22525,DB06724,10021097,133,7796,76,3843,0.334868278,0.862673299,0.644164982,1.162312927,0.504008972,DB0672410021097_,0.68516121,-0.147719224,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,calcium carbonate,DB06724
,22527,DB00169,10029354,305,38386,183,17992,0.00970536,0.781218907,0.647657274,0.944341198,0.034751538,DB0016910029354_,3.359531452,-0.246899877,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,22528,DB00186,10029354,207,16694,120,9888,0.908366732,1.02173238,0.810903556,1.292150572,0.959007895,DB0018610029354_,0.041855972,0.021499598,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,lorazepam,DB00186
,22529,DB00207,10029354,48,9032,44,5411,0.051232304,0.653600247,0.424385624,1.008715797,0.127356041,DB0020710029354_,2.06076864,-0.425259358,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,azithromycin,DB00207
,22530,DB00213,10029354,99,18796,162,13259,2.87664140365624e-11,0.431095692,0.331928825,0.5575648,1.02317346813402e-09,DB0021310029354_,20.7003568,-0.841425191,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,pantoprazole,DB00213
,22532,DB00433,10029354,227,7429,156,5864,0.192247148,1.148565701,0.929825609,1.421662271,0.339481978,DB0043310029354_,1.080334417,0.138513947,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,prochlorperazine,DB00433
,22533,DB00512,10029354,68,4669,97,5001,0.083615166,0.750902951,0.541027756,1.037266549,0.184450894,DB0051210029354_,1.690372008,-0.286478862,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,vancomycin,DB00512
,22534,DB00646,10029354,53,3400,46,1954,0.045540817,0.66224174,0.435802299,1.009443351,0.116602413,DB0064610029354_,2.148985314,-0.412124623,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,nystatin,DB00646
,22536,DB00694,10029354,50,584,59,712,0.920263767,1.033191331,0.682906947,1.55816523,0.964711792,DB0069410029354_,0.035925884,0.032652392,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,daunorubicin,DB00694
,22537,DB00706,10029354,7,1068,147,15778,0.503375682,0.703492868,0.277266591,1.491571908,0.664518597,DB0070610029354_,0.408692414,-0.35169754,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,tamsulosin,DB00706
,22539,DB00761,10029354,173,15134,112,8513,0.263945855,0.868884704,0.680044958,1.113837521,0.425828866,DB0076110029354_,0.853717736,-0.140544839,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,potassium chloride,DB00761
,22540,DB00787,10029354,305,16695,352,16896,0.098091196,0.876913182,0.748604328,1.026729745,0.207971533,DB0078710029354_,1.570354069,-0.131347286,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,acyclovir,DB00787
,22541,DB00836,10029354,63,5472,48,4027,0.847600927,0.965892351,0.651472418,1.440137782,0.923700341,DB0083610029354_,0.079367567,-0.034702889,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,loperamide,DB00836
,22542,DB00860,10029354,24,1859,42,1454,0.001624642,0.447040555,0.257659646,0.75944966,0.008199392,DB0086010029354_,4.803695277,-0.805105962,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,prednisolone,DB00860
,22543,DB00987,10029354,142,1962,203,2725,0.82119714,0.971540598,0.772226255,1.219752042,0.904725148,DB0098710029354_,0.100124085,-0.028872222,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,cytarabine,DB00987
,22546,DB06724,10029354,107,7822,63,3856,0.285786476,0.837289585,0.606129104,1.164824288,0.450448087,DB0672410029354_,0.797512443,-0.177585288,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,calcium carbonate,DB06724
,22548,DB00169,10033318,148,38543,61,18114,0.414276747,1.140242298,0.840293979,1.56371301,0.583577497,DB0016910033318_,0.538578022,0.131240782,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,22549,DB00186,10033318,53,16848,48,9960,0.038599415,0.652785342,0.432928132,0.986350033,0.10282615,DB0018610033318_,2.274715579,-0.426506929,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,lorazepam,DB00186
,22550,DB00207,10033318,48,9032,27,5428,0.812352883,1.068401314,0.65252956,1.783089167,0.899071824,DB0020710033318_,0.106392355,0.066163432,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,azithromycin,DB00207
,22551,DB00213,10033318,115,18780,50,13371,0.003301487,1.637528473,1.164214018,2.332230657,0.014619204,DB0021310033318_,4.225419272,0.493188077,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,22555,DB00512,10033318,30,4707,28,5070,0.600687801,1.154038186,0.665161901,2.008017815,0.745049021,DB0051210033318_,0.294305262,0.143267258,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,vancomycin,DB00512
,22561,DB00761,10033318,152,15155,51,8574,0.000933126,1.686133622,1.218966529,2.365968763,0.005201406,DB0076110033318_,5.25882639,0.52243811,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,22568,DB06724,10033318,39,7890,11,3908,0.099688307,1.756025878,0.880831587,3.80624598,0.210297523,DB0672410033318_,1.559231974,0.563053232,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,calcium carbonate,DB06724
,22571,DB00646,10037660,106,3347,97,1903,0.001052659,0.621348951,0.464505855,0.832006833,0.005750028,DB0064610037660_,5.158550547,-0.475862437,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,22572,DB00684,10037660,49,2743,77,2271,0.000534238,0.52693462,0.358930588,0.76720907,0.003258489,DB0068410037660_,5.726491735,-0.6406788,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,tobramycin,DB00684
,22573,DB00694,10037660,57,577,68,703,0.925200981,1.02127195,0.69285856,1.500930544,0.967955253,DB0069410037660_,0.032569419,0.02104886,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,daunorubicin,DB00694
,22574,DB00706,10037660,17,1058,292,15633,0.637190475,0.860246906,0.492368484,1.408378922,0.774499498,DB0070610037660_,0.255538267,-0.150535831,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,22575,DB00760,10037660,44,736,71,944,0.284822928,0.794956995,0.526207654,1.189912651,0.449360503,DB0076010037660_,0.79992981,-0.22946726,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,meropenem,DB00760
,22576,DB00836,10037660,144,5391,99,3976,0.645464936,1.072772861,0.821937812,1.404746303,0.78117292,DB0083610037660_,0.246958745,0.070246755,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,22577,DB01275,10037660,54,3925,63,3286,0.076217199,0.717636905,0.487970244,1.052243121,0.171822897,DB0127510037660_,1.761291,-0.331791542,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,22578,DB06724,10037660,218,7711,123,3796,0.242869785,0.872520062,0.693819756,1.101250773,0.40110787,DB0672410037660_,0.913524886,-0.136369632,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,22580,DB00169,10040047,308,38383,290,17885,3.73172128710327e-17,0.494874764,0.419755984,0.583612584,2.92800877705998e-15,DB0016910040047_,33.4644538,-0.703450551,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,22581,DB00186,10040047,197,16704,200,9808,8.02901961582314e-08,0.5783964,0.471864027,0.708862219,1.48204199860893e-06,DB0018610040047_,13.42208969,-0.547495832,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,lorazepam,DB00186
,22582,DB00207,10040047,64,9016,72,5383,0.000248087,0.530719819,0.372306826,0.755088223,0.00172398,DB0020710040047_,6.363119753,-0.633521045,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,azithromycin,DB00207
,22584,DB00335,10040047,81,8385,53,5412,0.929438397,0.986421803,0.687978143,1.424738491,0.970939263,DB0033510040047_,0.029491364,-0.013671224,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,atenolol,DB00335
,22585,DB00433,10040047,161,7495,155,5865,0.075397884,0.812829301,0.646067527,1.022872028,0.170472959,DB0043310040047_,1.769178592,-0.207234154,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,22586,DB00512,10040047,161,4576,146,4952,0.13160667,1.193325686,0.944333709,1.508943852,0.258039782,DB0051210040047_,1.354641512,0.176744103,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,vancomycin,DB00512
,22587,DB00646,10040047,99,3354,73,1927,0.126383984,0.779220031,0.566955088,1.075062716,0.250624894,DB0064610040047_,1.383797904,-0.24946182,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,nystatin,DB00646
,22589,DB00706,10040047,14,1061,250,15675,0.609347987,0.827332801,0.444235756,1.420953353,0.75180301,DB0070610040047_,0.285280944,-0.189548245,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,tamsulosin,DB00706
,22590,DB00761,10040047,294,15013,202,8423,0.029698335,0.816592006,0.67893391,0.983676339,0.084041637,DB0076110040047_,2.476442925,-0.20261569,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,22591,DB00836,10040047,90,5445,88,3987,0.056058312,0.748904767,0.550324846,1.019413537,0.136196423,DB0083610040047_,1.99365715,-0.28914345,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,loperamide,DB00836
,22592,DB01275,10040047,42,3937,72,3277,0.0001949,0.485586149,0.322772023,0.722449224,0.001409924,DB0127510040047_,6.564219717,-0.722398563,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,hydralazine,DB01275
,22593,DB06724,10040047,101,7828,84,3835,0.000495933,0.589069221,0.435468165,0.798635751,0.003071177,DB0672410040047_,5.785694382,-0.52921158,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,22595,DB00169,10045555,63,38628,40,18135,0.139338396,0.739409263,0.489558043,1.128545242,0.268926481,DB0016910045555_,1.31331724,-0.301903705,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,22596,DB00186,10045555,84,16817,74,9934,0.013196497,0.670573654,0.484211327,0.930233862,0.044407875,DB0018610045555_,3.114338452,-0.399621734,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,22598,DB00213,10045555,50,18845,63,13358,0.002866195,0.562591661,0.379910288,0.829194314,0.013030284,DB0021310045555_,4.340479063,-0.575201206,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,22602,DB00512,10045555,29,4708,53,5045,0.01996947,0.586369997,0.358812545,0.940912095,0.061690959,DB0051210045555_,2.785617885,-0.533804294,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,vancomycin,DB00512
,22608,DB00761,10045555,41,15266,37,8588,0.043984746,0.623358022,0.38954402,1.000684702,0.113575229,DB0076110045555_,2.17528985,-0.472634252,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,22610,DB00836,10045555,25,5510,42,4033,0.001096922,0.435714401,0.254037303,0.73307015,0.005941192,DB0083610045555_,5.125845415,-0.830768294,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,22681,DB00619,10011906,119,2780,168,2326,1.92838243159708e-05,0.592722305,0.461598256,0.759214944,0.00019339,DB0061910011906_,8.550801422,-0.523029278,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,22685,DB00641,10002424,34,14090,43,12432,0.136742972,0.69766953,0.431163826,1.120719942,0.26515137,DB0064110002424_,1.32745441,-0.360009742,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,22686,DB00999,10002424,112,21318,339,11900,5.99589628617693e-64,0.184435309,0.147403713,0.229306561,5.83711606970965e-61,DB0099910002424_,138.6934538,-1.690456506,male,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,22690,DB00575,10037844,117,5127,66,3763,0.096265933,1.301068582,0.951098158,1.792437153,0.205127481,DB0057510037844_,1.584123636,0.263185913,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,clonidine,DB00575
,22692,DB01067,10037844,99,4262,105,4718,0.777071197,1.043748185,0.78245107,1.391401702,0.878512755,DB0106710037844_,0.129524852,0.042818258,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,glipizide,DB01067
,22693,DB04854,10037844,59,722,96,1390,0.336081202,1.183097834,0.829861423,1.675390658,0.505198123,DB0485410037844_,0.682804603,0.168136281,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,febuxostat,DB04854
,22694,DB08882,10037844,31,966,24,969,0.412246125,1.29550623,0.729871463,2.325259786,0.581620966,DB0888210037844_,0.541936305,0.25890153,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,linagliptin,DB08882
,22695,DB08908,10010774,106,10567,44,3235,0.099422173,0.737540898,0.513091509,1.075939978,0.209999726,DB0890810010774_,1.560649054,-0.304433738,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,22703,DB00227,10041349,36,2431,20,1783,0.343448862,1.320112739,0.741116935,2.415444484,0.512754365,DB0022710041349_,0.66795837,0.277717142,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,lovastatin,DB00227
,22704,DB00321,10041349,98,7349,38,2812,0.923405738,0.986801946,0.670210091,1.479448437,0.966615684,DB0032110041349_,0.033954294,-0.013285923,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,22705,DB00451,10041349,582,46689,159,15260,0.048315549,1.196362889,1.00123088,1.436208382,0.121925327,DB0045110041349_,2.104346492,0.179286029,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,22706,DB00722,10041349,283,25120,201,25831,6.78920770642181e-05,1.447792939,1.203027552,1.744983023,0.000571877,DB0072210041349_,7.466586027,0.370040286,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,22710,DB00641,10002855,199,13925,123,12352,0.001634613,1.43510282,1.138884964,1.814318098,0.00824047,DB0064110002855_,4.798697923,0.361236498,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,22711,DB09068,10002855,87,2308,40,946,0.551508089,0.891524147,0.601286708,1.341479553,0.705529192,DB0906810002855_,0.348807131,-0.114822756,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,vortioxetine,DB09068
,22715,DB00641,10042458,30,14094,36,12439,0.219288681,0.735491558,0.437275031,1.228960299,0.372629374,DB0064110042458_,0.98717099,-0.307216217,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,22716,DB00999,10042458,88,21342,45,12194,0.588453939,1.117341832,0.771024644,1.63902102,0.735375082,DB0099910042458_,0.307374594,0.1109525,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,22717,DB09068,10042458,80,2315,45,941,0.088944349,0.722700355,0.491246036,1.07448891,0.193502914,DB0906810042458_,1.642462706,-0.32476059,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,vortioxetine,DB09068
,22720,DB00641,10021015,53,14071,25,12450,0.008794665,1.875724045,1.144483385,3.151803351,0.032120019,DB0064110021015_,3.438275799,0.628994742,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,simvastatin,DB00641
,22721,DB00656,10021015,57,11956,13,6606,0.002486535,2.422513132,1.308988209,4.827803579,0.011616204,DB0065610021015_,4.455354289,0.884805485,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,trazodone,DB00656
,22722,DB00736,10021015,64,10527,15,5538,0.004049541,2.24449234,1.263233267,4.245073874,0.017258564,DB0073610021015_,4.059446798,0.808479366,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,esomeprazole,DB00736
,22724,DB01069,10021015,41,6659,9,2386,0.200756169,1.632312816,0.779939971,3.825678452,0.349867456,DB0106910021015_,1.050200894,0.489997915,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,promethazine,DB01069
,22730,DB00641,10021036,47,14077,46,12429,0.677459127,0.902127746,0.587396833,1.386240218,0.80448507,DB0064110021036_,0.217552871,-0.102999143,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,simvastatin,DB00641
,22731,DB00736,10021036,32,10559,23,5530,0.256883519,0.728703778,0.412817558,1.305444227,0.417781419,DB0073610021036_,0.872796904,-0.31648797,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,esomeprazole,DB00736
,22733,DB00996,10021036,95,38858,60,22365,0.616418714,0.911301966,0.65247037,1.28148047,0.757571754,DB0099610021036_,0.277637021,-0.09288097,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,22734,DB01050,10021036,37,18071,38,9333,0.003248738,0.502870286,0.310795956,0.813068863,0.014429059,DB0105010021036_,4.238511097,-0.687423023,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,ibuprofen,DB01050
,22735,DB01068,10021036,31,13732,20,6820,0.373494467,0.769844123,0.424654381,1.426204699,0.543262801,DB0106810021036_,0.610162097,-0.261567222,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,clonazepam,DB01068
,22737,DB01224,10021036,32,8076,23,5894,1,1.015396869,0.575247874,1.819125818,1,DB0122410021036_,0,0.01527954,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,quetiapine,DB01224
,22739,DB00316,10034829,71,65403,26,36927,0.057529289,1.541805195,0.971184232,2.518461122,0.1387937,DB0031610034829_,1.974766621,0.432953934,NA,10034829,Pharyngeal oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,22740,DB00338,10034829,30,33644,20,22252,1,0.992092614,0.544928173,1.843714243,1,DB0033810034829_,0,-0.007938815,NA,10034829,Pharyngeal oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,22747,DB00996,10034829,43,38910,20,22405,0.513116252,1.238039622,0.712464645,2.222105474,0.67318496,DB0099610034829_,0.395735158,0.213529179,NA,10034829,Pharyngeal oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,22756,DB00316,10034839,72,65402,19,36934,0.002111803,2.139985231,1.276344725,3.758300341,0.010172026,DB0031610034839_,4.588113845,0.760798928,NA,10034839,Pharyngitis streptococcal,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,22757,DB00338,10034839,37,33637,16,22256,0.162778547,1.530058716,0.830241932,2.946767596,0.301068438,DB0033810034839_,1.200417671,0.425306111,NA,10034839,Pharyngitis streptococcal,10021881,Infections and infestations,Infec,omeprazole,DB00338
,22772,DB00230,10042674,232,19442,66,8585,0.001521485,1.552162701,1.174620466,2.075111795,0.007782863,DB0023010042674_,4.855831039,0.439649249,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,22777,DB00252,10010264,52,2180,24,1884,0.010545779,1.872201112,1.128533921,3.188489988,0.037132726,DB0025210010264_,3.293256596,0.627114804,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,phenytoin,DB00252
,22778,DB00776,10010264,42,1863,30,1309,1,0.983682711,0.597674757,1.636919539,1,DB0077610010264_,0,-0.016451882,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,oxcarbazepine,DB00776
,22788,DB00068,10016256,169,2065,37,628,0.08534289,1.388889802,0.956259274,2.063221485,0.187311111,DB0006810016256_,1.674984347,0.328504724,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,22789,DB00091,10000081,67,5443,30,2640,0.827619944,1.083213815,0.692440986,1.730787403,0.9093147,DB0009110000081_,0.09506404,0.079932377,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,cyclosporine,DB00091
,22790,DB00215,10000081,152,10951,35,5241,3.86820398688833e-05,2.078352073,1.428970939,3.098402445,0.000354765,DB0021510000081_,7.944054047,0.731575307,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,22791,DB00051,10022687,113,25618,71,11349,0.024657854,0.705069564,0.51896012,0.963430811,0.072759255,DB0005110022687_,2.62059916,-0.349458808,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,22793,DB00186,10022687,50,16851,20,9988,0.172610864,1.481790291,0.865789235,2.62943764,0.314276365,DB0018610022687_,1.157482537,0.393251013,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,22794,DB00193,10022687,46,19274,13,8689,0.158935242,1.595165827,0.846851147,3.22010874,0.296085108,DB0019310022687_,1.217108339,0.466977698,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,22796,DB00635,10022687,83,32970,47,23747,0.212708576,1.27194405,0.878578447,1.860669597,0.364665074,DB0063510022687_,1.008775952,0.240546478,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,22797,DB00091,10028813,274,5236,90,2580,0.000890454,1.50005785,1.17217545,1.934404049,0.005007613,DB0009110028813_,5.296795969,0.405503674,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cyclosporine,DB00091
,22798,DB00215,10028813,658,10445,174,5102,1.4848508756269e-13,1.84711466,1.555067807,2.203069343,7.4412402794763e-12,DB0021510028813_,25.62398358,0.613624778,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,22799,DB00051,10029148,75,25656,50,11370,0.032132033,0.664763981,0.458336887,0.971389941,0.089393573,DB0005110029148_,2.414706488,-0.408323217,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,adalimumab,DB00051
,22801,DB00186,10029148,49,16852,25,9983,0.630300115,1.161113205,0.702860724,1.963127284,0.769236844,DB0018610029148_,0.262356367,0.149379204,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,lorazepam,DB00186
,22803,DB00635,10029148,106,32947,64,23730,0.276579206,1.19289267,0.866160962,1.654129354,0.440014982,DB0063510029148_,0.820946502,0.176381173,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,22804,DB00051,10047700,432,25299,132,11288,0.000109254,1.460240315,1.197288506,1.79055283,0.000860107,DB0005110047700_,7.058453455,0.378601022,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,22805,DB00091,10047700,131,5379,47,2623,0.075628362,1.359128715,0.963511672,1.945943178,0.170832424,DB0009110047700_,1.767072182,0.306843843,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cyclosporine,DB00091
,22813,DB00996,10008796,36,38917,25,22400,0.506585735,0.82885255,0.483841757,1.440852876,0.667330466,DB0099610008796_,0.404469905,-0.187713005,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,22815,DB00158,10037844,536,16279,199,7905,0.001370809,1.307956458,1.106938285,1.550283408,0.007142038,DB0015810037844_,4.941757085,0.268465964,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,22816,DB00395,10037844,43,2141,15,721,0.879373807,0.965384222,0.522015224,1.882492478,0.949348846,DB0039510037844_,0.051978954,-0.035229099,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,carisoprodol,DB00395
,22817,DB00829,10037844,196,7856,63,4391,0.000102089,1.738840064,1.299476829,2.353879556,0.000812419,DB0082910037844_,7.115494367,0.553218261,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,diazepam,DB00829
,22818,DB00996,10037844,973,37980,465,21960,0.000795168,1.209819102,1.08078916,1.355845662,0.00455161,DB0099610037844_,5.392274248,0.190470846,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,22819,DB08895,10037844,922,27192,198,6448,0.231110882,1.104201333,0.943671639,1.297164175,0.387259716,DB0889510037844_,0.948659711,0.099122298,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,22829,DB00065,10007882,51,9413,32,4925,0.419268927,0.833892109,0.524946077,1.342748951,0.588339628,DB0006510007882_,0.5304509,-0.181651251,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,infliximab,DB00065
,22835,DB00203,10021143,358,13520,169,8769,0.000697564,1.373926895,1.138708325,1.663070049,0.004079538,DB0020310021143_,5.501771568,0.317672987,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,22836,DB00374,10021143,385,17331,160,5564,0.007479531,0.772519387,0.639132381,0.937172195,0.028230827,DB0037410021143_,3.567340758,-0.258098175,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,22837,DB00559,10021143,166,9493,74,3232,0.061447697,0.763754682,0.575556675,1.021618615,0.146121384,DB0055910021143_,1.923317607,-0.269508638,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,22840,DB00480,10003988,888,66540,742,66920,0.000223898,1.203596578,1.089911112,1.32943397,0.001583736,DB0048010003988_,6.447968909,0.185314222,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,22841,DB00555,10061422,40,7007,30,3456,0.096877065,0.657640206,0.398709588,1.095469819,0.206098909,DB0055510061422_,1.579399084,-0.419097297,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,22851,DB00121,10008531,56,4167,10,458,0.149825977,0.615583078,0.308449635,1.362824469,0.283686525,DB0012110008531_,1.259885437,-0.485185365,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,22852,DB00175,10008531,60,8071,40,6066,0.612634271,1.127325753,0.742114203,1.728998201,0.754508226,DB0017510008531_,0.281689099,0.119848238,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,22853,DB00656,10008531,96,11917,44,6575,0.330492621,1.203736424,0.832963625,1.763749447,0.499195412,DB0065610008531_,0.694757653,0.185430406,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,22854,DB01050,10008531,168,17940,85,9286,0.894157554,1.023049138,0.782527161,1.345880132,0.955860142,DB0105010008531_,0.045143671,0.022787519,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,22855,DB06228,10008531,54,15858,38,16038,0.094782863,1.437159417,0.931024884,2.238515208,0.20292169,DB0622810008531_,1.59493514,0.362668538,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,22856,DB13961,10008531,88,9369,56,6358,0.733653505,1.066410375,0.753024997,1.521072731,0.84555203,DB1396110008531_,0.167765575,0.064298219,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,22858,DB00175,10022000,127,8004,51,6055,9.37837054109418e-05,1.883732561,1.348550705,2.665669182,0.000755427,DB0017510022000_,7.188227459,0.633255213,NA,10022000,Influenza,10021881,Infections and infestations,Infec,pravastatin,DB00175
,22859,DB00264,10022000,290,29317,220,24672,0.264234697,1.109297291,0.927001704,1.32900354,0.426151,DB0026410022000_,0.852961535,0.103726743,NA,10022000,Influenza,10021881,Infections and infestations,Infec,metoprolol,DB00264
,22860,DB01050,10022000,168,17940,110,9261,0.056447902,0.788436705,0.615431645,1.013395205,0.136888898,DB0105010022000_,1.988585644,-0.237703149,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,22861,DB01373,10022000,250,22470,94,7287,0.23107159,0.862524771,0.676730907,1.107003859,0.387206676,DB0137310022000_,0.948796682,-0.14789141,NA,10022000,Influenza,10021881,Infections and infestations,Infec,calcium,DB01373
,22862,DB06228,10022000,84,15828,68,16008,0.193202763,1.249330759,0.895911791,1.747629477,0.340656356,DB0622810022000_,1.076881063,0.222608015,NA,10022000,Influenza,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,22863,DB13961,10022000,107,9350,53,6361,0.062588604,1.373450547,0.977619298,1.949845704,0.148277734,DB1396110022000_,1.908668182,0.317326221,NA,10022000,Influenza,10021881,Infections and infestations,Infec,fish oil,DB13961
,22865,DB00175,10023232,79,8052,30,6076,0.001242288,1.986994156,1.28814179,3.138879392,0.006579397,DB0017510023232_,5.023812152,0.686623022,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,22866,DB00264,10023232,248,29359,129,24763,7.45971829003656e-06,1.621507706,1.304549298,2.023406257,8.39557676101952e-05,DB0026410023232_,9.385220474,0.483356399,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,22867,DB00588,10023232,134,16390,55,8413,0.189521484,1.250533481,0.906146865,1.746456519,0.335934466,DB0058810023232_,1.090839179,0.223570245,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,22868,DB00656,10023232,73,11940,25,6594,0.043810737,1.612564288,1.010404169,2.654252152,0.11320213,DB0065610023232_,2.178580295,0.477825637,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,22869,DB01050,10023232,151,17957,72,9299,0.619662064,1.086036971,0.813968237,1.460464045,0.760331312,DB0105010023232_,0.274001004,0.082535264,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,22870,DB01373,10023232,222,22498,61,7320,0.266763723,1.184095079,0.887087428,1.601049956,0.428979503,DB0137310023232_,0.846346139,0.168978837,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,22871,DB06228,10023232,64,15848,46,16030,0.085386326,1.407260891,0.947881123,2.103696572,0.187362742,DB0622810023232_,1.674708743,0.341645185,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,rivaroxaban,DB06228
,22872,DB13961,10023232,118,9339,43,6371,0.000352917,1.871989304,1.30785238,2.72396322,0.002308427,DB1396110023232_,6.071188995,0.627001665,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,22873,DB00175,10028411,166,7965,90,6016,0.012816563,1.393083864,1.068934313,1.82522619,0.043398824,DB0017510028411_,3.13732294,0.331519897,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,22874,DB00264,10028411,311,29296,187,24705,0.000246991,1.402464187,1.165115131,1.691875393,0.001717502,DB0026410028411_,6.366884211,0.338230823,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,22875,DB00656,10028411,135,11878,51,6568,0.020770149,1.46367613,1.051558254,2.064893635,0.063674289,DB0065610028411_,2.753974424,0.380951168,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,22876,DB01050,10028411,192,17916,85,9286,0.25152668,1.1707421,0.901131083,1.531698813,0.41151368,DB0105010028411_,0.887913014,0.157637821,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,22877,DB06228,10028411,135,15777,72,16004,7.22175678368611e-06,1.901928063,1.417194178,2.570504755,8.16095774115174e-05,DB0622810028411_,9.413563933,0.642868141,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,rivaroxaban,DB06228
,22878,DB13961,10028411,136,9321,71,6343,0.074793513,1.303483362,0.969409643,1.765391149,0.16950015,DB1396110028411_,1.774901466,0.26504019,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,22879,DB00121,10028810,82,4141,9,459,1,1.00989901,0.502352531,2.302375158,1,DB0012110028810_,0,0.009850336,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,biotin,DB00121
,22880,DB00175,10028810,133,7998,54,6052,9.95001404374682e-05,1.863607454,1.34601809,2.611613869,0.000793616,DB0017510028810_,7.13891097,0.622514101,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,pravastatin,DB00175
,22881,DB00588,10028810,291,16233,131,8337,0.232856185,1.140844831,0.923443335,1.41554334,0.389362173,DB0058810028810_,0.943245333,0.131769068,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,22882,DB00656,10028810,152,11861,48,6571,0.000596092,1.754285726,1.25857081,2.483874007,0.003576413,DB0065610028810_,5.633394806,0.56206178,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,trazodone,DB00656
,22883,DB01050,10028810,262,17846,114,9257,0.125194626,1.192105018,0.951765707,1.50089675,0.248874323,DB0105010028810_,1.390807236,0.175720667,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,22884,DB01373,10028810,453,22267,108,7273,0.002941546,1.369982228,1.106362729,1.708926588,0.013291823,DB0137310028810_,4.320606245,0.314797767,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,calcium,DB01373
,22885,DB06228,10028810,148,15764,64,16012,3.1447171545618e-09,2.348929183,1.73903439,3.203321902,7.90615881469699e-08,DB0622810028810_,16.35303869,0.853959558,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,22886,DB13961,10028810,195,9262,104,6310,0.049475169,1.277377086,0.999482283,1.640302861,0.12402411,DB1396110028810_,2.087279297,0.244808824,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,fish oil,DB13961
,22887,DB00175,10033371,352,7779,151,5955,2.0298334549419e-09,1.784446926,1.465939378,2.180609961,5.29569949013874e-08,DB0017510033371_,16.75378567,0.579108522,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,22888,DB00656,10033371,522,11491,168,6451,1.6180370334579e-10,1.744287776,1.459063804,2.093835344,5.10259189255441e-09,DB0065610033371_,19.09351721,0.556346321,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,22889,DB01050,10033371,987,17121,296,9075,1.52595228603721e-18,1.767398157,1.54656035,2.024465597,1.38309158063752e-16,DB0105010033371_,36.51704022,0.569508497,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,22890,DB06228,10033371,278,15634,153,15923,5.7233940190502e-10,1.85053362,1.511819784,2.27209251,1.66102045545442e-08,DB0622810033371_,17.9132486,0.615474041,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,22891,DB13961,10033371,418,9039,185,6229,5.51149891562718e-07,1.557006462,1.302324301,1.867123708,8.46449015467488e-06,DB1396110033371_,11.67963077,0.442765043,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,22892,DB00121,10040753,100,4123,7,461,0.324883721,1.597177075,0.740997989,4.099709079,0.493335756,DB0012110040753_,0.70656529,0.468237743,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,biotin,DB00121
,22893,DB00175,10040753,127,8004,34,6072,7.45460567768256e-09,2.833411642,1.924359704,4.274429931,1.72258734275065e-07,DB0017510040753_,15.57426822,1.041481513,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,pravastatin,DB00175
,22894,DB00588,10040753,603,15921,157,8311,4.90441142249377e-16,2.004885286,1.675683847,2.410133136,3.40138401689311e-14,DB0058810040753_,31.01200889,0.695586845,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,22895,DB00656,10040753,169,11844,35,6584,9.24362657017612e-09,2.684041817,1.853635868,3.986579932,2.09546118496834e-07,DB0065610040753_,15.37832199,0.987323799,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,trazodone,DB00656
,22896,DB01050,10040753,311,17797,95,9276,3.12911403679609e-06,1.706250859,1.349850204,2.173373848,3.927830107793e-05,DB0105010040753_,10.14483833,0.534298483,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,22897,DB06228,10040753,91,15821,34,16042,2.03054028959216e-07,2.713891709,1.810405737,4.154283653,3.44028834582779e-06,DB0622810040753_,12.57995527,0.99838366,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,22898,DB13961,10040753,206,9251,63,6351,3.97530782634996e-09,2.244693843,1.68188733,3.03167403,9.76094966983735e-08,DB1396110040753_,16.14229105,0.808569139,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,fish oil,DB13961
,22899,DB00175,10052904,56,8075,25,6081,0.032002691,1.686800263,1.033938422,2.82470721,0.089109189,DB0017510052904_,2.417892819,0.522833399,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,22900,DB00656,10052904,73,11940,23,6596,0.018343401,1.753312049,1.083148163,2.939279228,0.057708712,DB0065610052904_,2.852347125,0.561506599,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,22901,DB01373,10052904,160,22560,27,7354,0.00085019,1.931563429,1.277881159,3.024852262,0.00481547,DB0137310052904_,5.335921595,0.658329742,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,22903,DB13961,10052904,85,9372,34,6380,0.008467178,1.701820841,1.129344216,2.616498494,0.031167041,DB1396110052904_,3.468394121,0.531698761,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,22904,DB00374,10003658,235,17481,77,5647,0.894627119,0.985890637,0.757659378,1.294808221,0.955976233,DB0037410003658_,0.045022227,-0.014209846,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,treprostinil,DB00374
,22905,DB00820,10003658,222,11693,96,5720,0.335195813,1.131217448,0.884492104,1.455755777,0.504400855,DB0082010003658_,0.684383979,0.123294441,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,tadalafil,DB00820
,22906,DB06403,10003658,182,21289,43,6618,0.115205392,1.315729661,0.938056786,1.882090795,0.233961135,DB0640310003658_,1.452600267,0.274391387,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ambrisentan,DB06403
,22910,DB00374,10013971,713,17003,225,5499,0.786023283,1.024871243,0.878161505,1.19965731,0.883876877,DB0037410013971_,0.123437505,0.024566988,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,22911,DB00820,10013971,628,11287,164,5652,1.66584697974905e-14,1.917453936,1.607067993,2.298101572,9.52922477969612e-13,DB0082010013971_,27.67924284,0.650998231,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,22912,DB06403,10013971,541,20930,139,6522,0.044539256,1.212800096,1.002584272,1.47507542,0.114657886,DB0640310013971_,2.165802489,0.192931815,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,22913,DB06403,10021097,733,20738,234,6427,0.700336149,0.970798954,0.834484997,1.132642678,0.819879108,DB0640310021097_,0.198598379,-0.029635882,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ambrisentan,DB06403
,22926,DB00904,10027599,220,22849,44,14412,1.35051407085708e-14,3.153649259,2.271347135,4.467581366,7.79325188857922e-13,DB0090410027599_,27.88034799,1.148560277,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,22929,DB00115,10053762,456,17969,220,10252,0.043020623,1.182599179,1.00272672,1.398013578,0.111725838,DB0011510053762_,2.191707284,0.167714711,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,22930,DB00158,10053762,510,16305,231,7873,0.449485935,1.066046369,0.908561704,1.253794441,0.617086483,DB0015810053762_,0.482746098,0.063956822,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,22931,DB00581,10053762,50,2063,59,2010,0.333392685,0.825725094,0.552009288,1.231016561,0.502420979,DB0058110053762_,0.688316907,-0.191493377,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lactulose,DB00581
,22932,DB00715,10053762,127,4716,62,2225,0.813227481,0.966453471,0.704679696,1.337162804,0.89968788,DB0071510053762_,0.105707376,-0.034122124,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,paroxetine,DB00715
,22933,DB01220,10053762,59,1235,41,1095,0.26089454,1.275767344,0.834525365,1.966428042,0.42238385,DB0122010053762_,0.861840782,0.243547836,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,rifaximin,DB01220
,22940,DB00853,10013709,76,1745,91,2175,0.81190301,1.040975244,0.752228315,1.437212749,0.89899083,DB0085310013709_,0.106482445,0.040158009,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,temozolomide,DB00853
,22945,DB00005,10017533,425,127657,70,42349,5.95409557137864e-09,2.014008793,1.560633826,2.632869047,1.40867148599179e-07,DB0000510017533_,15.7754486,0.70012716,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,22946,DB00904,10007515,168,22901,183,14273,2.51810376071274e-07,0.572192756,0.460771592,0.710165652,4.17460468939353e-06,DB0090410007515_,12.38649089,-0.558279359,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,ondansetron,DB00904
,22950,DB08911,10033371,36,1603,24,1724,0.089421021,1.612985669,0.931502559,2.839632428,0.194346911,DB0891110033371_,1.638110514,0.478086914,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,trametinib,DB08911
,22956,DB00820,10020751,117,11798,27,5789,0.00023088,2.126185966,1.387696568,3.36596459,0.001624594,DB0082010020751_,6.422497491,0.754329748,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,tadalafil,DB00820
,22957,DB08932,10020751,181,19262,29,6568,6.0237259079055e-05,2.128255901,1.430753302,3.271807811,0.000517684,DB0893210020751_,7.566145641,0.755302818,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,macitentan,DB08932
,22958,DB08932,10033775,142,19301,31,6566,0.022679994,1.558210293,1.049365834,2.381025,0.068157965,DB0893210033775_,2.685927253,0.443537915,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,22960,DB00373,10013700,50,1782,8,1279,9.41910848238274e-06,4.484126511,2.099886765,10.9942103,0.00010318,DB0037310013700_,9.179032063,1.500543719,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,timolol,DB00373
,22961,DB00005,10013887,37,128045,20,42399,0.090485359,0.612584973,0.346417404,1.114053646,0.196027303,DB0000510013887_,1.629501328,-0.490067614,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,22968,DB00451,10074902,72,47199,18,15401,0.390767018,1.305179911,0.770051083,2.325950634,0.560630483,DB0045110074902_,0.578693266,0.266340894,NA,10074902,Expired product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,22969,DB00695,10074902,33,28016,17,20511,0.254912081,1.421157582,0.768968471,2.721151181,0.415616664,DB0069510074902_,0.877991925,0.351471738,NA,10074902,Expired product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,22970,DB00722,10074902,35,25368,22,26010,0.084246393,1.631144746,0.930163304,2.919770689,0.185477548,DB0072210074902_,1.684821439,0.489282066,NA,10074902,Expired product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,22971,DB01076,10074902,39,25708,19,25564,0.011905556,2.041095843,1.151086817,3.740443676,0.040912596,DB0107610074902_,3.196317289,0.713486842,NA,10074902,Expired product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,22977,DB01202,10028334,47,6667,26,5692,0.078070886,1.543273999,0.935004794,2.599580289,0.175138109,DB0120210028334_,1.74218042,0.433906133,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,levetiracetam,DB01202
,22979,DB00555,10008531,51,6996,15,3471,0.087289861,1.686802275,0.93199843,3.234927425,0.190581775,DB0055510008531_,1.657673912,0.522834591,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,22980,DB01202,10008531,40,6674,19,5699,0.036058581,1.797620469,1.015757589,3.290206604,0.097643545,DB0120210008531_,2.326431732,0.586463829,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,22981,DB00555,10016322,126,6921,48,3438,0.123381434,1.303973039,0.925622254,1.863070627,0.246228911,DB0055510016322_,1.401493641,0.265415788,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,22982,DB01202,10016322,72,6642,40,5678,0.028681893,1.538697269,1.02953562,2.328939797,0.081790458,DB0120210016322_,2.503594692,0.430936129,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,22984,DB01202,10042772,39,6675,29,5689,0.626579836,1.146160229,0.689789954,1.924494726,0.766137181,DB0120210042772_,0.266394038,0.136417424,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,22985,DB00555,10047571,51,6996,23,3463,0.80447295,1.097589713,0.657448659,1.885045927,0.894353284,DB0055510047571_,0.111654409,0.093116606,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,lamotrigine,DB00555
,22986,DB01202,10047571,49,6665,20,5698,0.00501966,2.094372947,1.220494804,3.724304909,0.020529294,DB0120210047571_,3.88590244,0.739254199,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,levetiracetam,DB01202
,22987,DB00016,10011224,53,2709,50,2240,0.548912886,0.876510017,0.58168911,1.322417301,0.703367387,DB0001610011224_,0.351875924,-0.131807146,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,erythropoietin,DB00016
,22989,DB00016,10035664,90,2672,81,2209,0.585520134,0.918595433,0.669022951,1.262930005,0.733033113,DB0001610035664_,0.310564403,-0.084909479,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,erythropoietin,DB00016
,22990,DB00016,10037844,87,2675,56,2234,0.147442235,1.297382238,0.912200081,1.858065386,0.280387726,DB0001610037844_,1.271581898,0.260348571,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,erythropoietin,DB00016
,22993,DB00005,10033645,68,128014,32,42387,0.105386441,0.703615288,0.455744831,1.107298195,0.219186787,DB0000510033645_,1.517831004,-0.351523538,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,22998,DB00043,10013709,290,6123,138,2162,0.005812572,0.742038074,0.600079393,0.921010938,0.023080816,DB0004310013709_,3.768753469,-0.298354725,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,23002,DB00043,10069327,112,6301,31,2269,0.214318936,1.300955216,0.864469342,2.010250131,0.366660585,DB0004310069327_,1.003318694,0.263098776,NA,10069327,Product quality issue,10077536,Product issues,Prod,omalizumab,DB00043
,23003,DB01409,10069327,327,5704,156,3810,0.000698246,1.400084139,1.148155347,1.712994063,0.004082162,DB0140910069327_,5.501128619,0.336532334,NA,10069327,Product quality issue,10077536,Product issues,Prod,tiotropium,DB01409
,23007,DB00108,10042209,100,10094,17,3278,0.012470479,1.910097848,1.133212992,3.414176555,0.0424484,DB0010810042209_,3.159466047,0.64715447,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,natalizumab,DB00108
,23011,DB00398,10000081,36,691,102,1436,0.132231229,0.733559117,0.481755908,1.095464856,0.258982209,DB0039810000081_,1.350995909,-0.309847089,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,sorafenib,DB00398
,23013,DB00999,10000081,347,21083,137,12102,0.000198576,1.453881403,1.188040661,1.78734915,0.001432076,DB0099910000081_,6.548629987,0.37423681,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,23014,DB00398,10013573,25,702,53,1485,1,0.997823887,0.588930499,1.649976974,1,DB0039810013573_,0,-0.002178485,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sorafenib,DB00398
,23016,DB01069,10013573,218,6482,47,2348,0.001083743,1.680108829,1.216223931,2.362948747,0.005886183,DB0106910013573_,5.135147543,0.518858571,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,23017,DB00398,10015090,20,707,32,1506,0.367068957,1.331200785,0.716092091,2.419381241,0.536678581,DB0039810015090_,0.622355909,0.286081381,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sorafenib,DB00398
,23019,DB00999,10015090,127,21303,62,12177,0.325040725,1.170902208,0.856858003,1.614350805,0.493484403,DB0099910015090_,0.706264025,0.15777457,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,23020,DB00398,10016256,97,630,247,1291,0.102920381,0.804837789,0.617710704,1.042678797,0.215378545,DB0039810016256_,1.535358126,-0.217114526,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sorafenib,DB00398
,23022,DB01069,10016256,493,6207,171,2224,0.748857573,1.033031951,0.86026269,1.244975884,0.857491671,DB0106910016256_,0.153743813,0.03249812,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,23024,DB00425,10016807,75,12620,40,7444,0.629897148,1.105992188,0.742954618,1.668336888,0.768905704,DB0042510016807_,0.262786939,0.10074284,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,zolpidem,DB00425
,23026,DB01069,10016807,45,6655,14,2381,0.767112374,1.149974442,0.618528557,2.27283165,0.871974951,DB0106910016807_,0.136994582,0.139739717,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,promethazine,DB01069
,23027,DB00316,10018092,47,65427,42,36911,0.035360141,0.631290219,0.407384618,0.981195244,0.09618736,DB0031610018092_,2.341457319,-0.459989587,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,23036,DB00999,10018836,43,21387,31,12208,0.334318858,0.79179419,0.487170714,1.300546921,0.50339823,DB0099910018836_,0.686373713,-0.233453782,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,23038,DB00425,10028334,193,12502,106,7378,0.587445375,1.074515035,0.841914994,1.377485502,0.734498831,DB0042510028334_,0.308566875,0.07186943,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,23040,DB00999,10028334,389,21041,168,12071,0.002155575,1.328353435,1.104090927,1.603815783,0.010346838,DB0099910028334_,4.571074308,0.283940157,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,23043,DB00999,10040882,47,21383,27,12212,1,0.994150062,0.606275774,1.660918394,1,DB0099910040882_,0,-0.005867116,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,23045,DB00316,10042128,359,65115,143,36810,0.00032849,1.419193808,1.16543227,1.735808296,0.002174082,DB0031610042128_,6.13114888,0.35008897,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,23046,DB00425,10042128,74,12621,31,7453,0.128259293,1.409614232,0.914186659,2.221031839,0.253176292,DB0042510042128_,1.373669226,0.343316073,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,23048,DB00999,10042128,113,21317,53,12186,0.257693684,1.218764138,0.871267561,1.724000096,0.418549006,DB0099910042128_,0.870961297,0.197837343,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,23050,DB00316,10066152,93,65381,39,36914,0.123764201,1.346345895,0.916806914,2.01081312,0.246749244,DB0031610066152_,1.399382666,0.297394178,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,23057,DB00811,10000087,31,2767,39,4117,0.540554708,1.182649157,0.711594698,1.950391923,0.696067631,DB0081110000087_,0.362308453,0.16775697,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ribavirin,DB00811
,23059,DB00008,10028813,167,1358,86,1590,1.10861992803902e-09,2.273045913,1.723524516,3.01472935,3.05131673387495e-08,DB0000810028813_,17.30510753,0.821120744,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,peginterferon alfa-2a,DB00008
,23061,DB00008,10047700,77,1448,43,1633,0.000253566,2.019024455,1.362690211,3.025606928,0.001756945,DB0000810047700_,6.344178684,0.702614452,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,peginterferon alfa-2a,DB00008
,23062,DB00811,10047700,153,2645,150,4006,0.000247964,1.544702161,1.218352649,1.958809612,0.001723359,DB0081110047700_,6.363480113,0.434831116,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ribavirin,DB00811
,23068,DB00182,10001488,24,5170,44,2808,1.17872754492796e-06,0.296302213,0.171945511,0.499213578,1.65635007854584e-05,DB0018210001488_,11.00830903,-1.216375357,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,23069,DB00186,10001488,67,16834,88,9920,9.66558124665189e-07,0.448667468,0.321229505,0.624223349,1.38889676398028e-05,DB0018610001488_,11.18441573,-0.801473272,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,23071,DB00285,10001488,46,10905,17,3701,0.771999655,0.918334342,0.515775888,1.710959912,0.875164899,DB0028510001488_,0.133342955,-0.085193748,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,23072,DB00338,10001488,31,33643,50,22222,8.84420282462301e-05,0.409528847,0.252817891,0.654001221,0.000718609,DB0033810001488_,7.238193762,-0.892747935,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,23075,DB01156,10001488,21,13601,30,6298,0.000107312,0.324158267,0.176234177,0.585870309,0.00084769,DB0115610001488_,7.072995983,-1.126523404,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,23078,DB00285,10053762,254,10697,103,3615,0.123902785,0.833361831,0.65811848,1.061658408,0.246941251,DB0028510053762_,1.398604819,-0.18228736,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,23084,DB06643,10029410,47,52374,6,7509,1,1.123108771,0.478991266,3.215731607,1,DB0664310029410_,0,0.116100528,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,23088,DB01015,10030124,98,9789,83,9298,0.455866027,1.121492625,0.827392792,1.523177794,0.623273786,DB0101510030124_,0.472769394,0.114660499,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,23090,DB06626,10037844,11,677,39,1413,0.128082647,0.588814478,0.270241578,1.181364726,0.252951078,DB0662610037844_,1.374559178,-0.529644123,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,axitinib,DB06626
,23091,DB01015,10042674,48,9839,37,9344,0.384628307,1.232015189,0.784956953,1.947612089,0.554684391,DB0101510042674_,0.589355993,0.208651194,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,23096,DB00158,10005734,35,16780,22,8082,0.324762996,0.766291076,0.436792322,1.372176749,0.493205186,DB0015810005734_,0.706829993,-0.266193187,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,folic acid,DB00158
,23098,DB06228,10005734,62,15850,53,16023,0.4009144,1.182571997,0.805702619,1.741049458,0.570747843,DB0622810005734_,0.560807772,0.167691725,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,rivaroxaban,DB06228
,23102,DB00158,10022595,36,16779,16,8088,0.882647896,1.084564682,0.586316479,2.094594274,0.950991964,DB0015810022595_,0.050249667,0.081178692,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,folic acid,DB00158
,23103,DB00316,10022595,184,65290,149,36804,0.001110363,0.696143294,0.557580845,0.870210116,0.00600224,DB0031610022595_,5.115622621,-0.362199757,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,acetaminophen,DB00316
,23105,DB06228,10022595,133,15779,184,15892,0.005623321,0.728012549,0.577328123,0.915994836,0.022480456,DB0622810022595_,3.795108982,-0.317436994,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,rivaroxaban,DB06228
,23108,DB11089,10022595,39,10136,32,8375,1,1.007007671,0.614163783,1.661983914,1,DB1108910022595_,0,0.006983231,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,docusate,DB11089
,23110,DB00722,10046274,45,25358,71,25961,0.02536412,0.64888296,0.436270595,0.956321989,0.074300221,DB0072210046274_,2.599641347,-0.432502917,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,23112,DB01076,10046274,31,25716,80,25503,2.32127896107624e-06,0.384278671,0.245166517,0.588748829,3.01605622797276e-05,DB0107610046274_,10.40897537,-0.956387284,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,23113,DB06228,10046274,237,15675,380,15696,1.39635265726026e-08,0.62453277,0.527931946,0.737605616,3.03457045027582e-07,DB0622810046274_,15.00802577,-0.470751477,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,23119,DB00635,10022052,252,32801,48,23746,5.80736128173326e-22,3.800581576,2.780730582,5.291460747,7.37422663238448e-20,DB0063510022052_,44.05371083,1.335154101,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,23120,DB00635,10022093,314,32739,30,23764,7.85621748002224e-43,7.595428021,5.213416289,11.45613791,3.50001146546415e-40,DB0063510022093_,90.85063748,2.02754649,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,23121,DB00635,10037855,97,32956,65,23729,0.690479986,1.074505711,0.7763983,1.495333377,0.813284927,DB0063510037855_,0.206673767,0.071860752,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,23122,DB00005,10043528,77,128005,12,42407,0.013498327,2.12564504,1.149670475,4.292515558,0.045203661,DB0000510043528_,3.096577195,0.754075305,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,23123,DB00635,10053425,270,32783,35,23759,2.94203948736044e-31,5.59067423,3.920215546,8.197537519,7.16032480789529e-29,DB0063510053425_,64.80641235,1.721099894,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,23127,DB00005,10050505,122,127960,69,42350,0.00055577,0.5851833,0.431960114,0.798159013,0.0033691,DB0000510050505_,5.693109628,-0.535830148,NA,10050505,Spinal fusion surgery,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,23128,DB11089,10011906,485,9690,575,7832,1.74029083372527e-09,0.681769646,0.600681095,0.773551875,4.6019662539707e-08,DB1108910011906_,16.89419709,-0.38306344,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,23147,DB00564,10022523,41,2563,28,1435,0.448531825,0.819892116,0.49253659,1.383005425,0.616227211,DB0056410022523_,0.484139534,-0.198582513,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,carbamazepine,DB00564
,23151,DB00005,10013789,67,128015,14,42405,0.123705012,1.58521595,0.882185402,3.05467249,0.246678013,DB0000510013789_,1.399671384,0.460720644,NA,10013789,Dry throat,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,23154,DB00635,10028334,394,32659,180,23614,2.41700858198251e-07,1.58265456,1.32233411,1.900047276,4.02605009996262e-06,DB0063510028334_,12.42272479,0.459103538,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,23163,DB00575,10069326,21,5223,31,3798,0.015823436,0.492630219,0.268610651,0.886745148,0.051408092,DB0057510069326_,2.967959683,-0.70799645,NA,10069326,Product substitution issue,10077536,Product issues,Prod,clonidine,DB00575
,23171,DB01268,10047895,120,2023,199,2931,0.264375902,0.87371598,0.685707624,1.109542974,0.426313339,DB0126810047895_,0.852580665,-0.134999922,NA,10047895,Weight decreased,10022891,Investigations,Inv,sunitinib,DB01268
,23174,DB00230,10043431,132,19542,28,8623,0.000199012,2.080154942,1.374107108,3.252017718,0.001434145,DB0023010043431_,6.547186543,0.732442382,NA,10043431,Thinking abnormal,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,23182,DB00682,10049848,110,19349,98,16266,0.676124982,0.943631683,0.711535813,1.252874568,0.803760353,DB0068210049848_,0.218454123,-0.058019355,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,23183,DB08932,10049848,91,19352,44,6553,0.059035313,0.700341079,0.482932018,1.029056144,0.141672892,DB0893210049848_,1.954234453,-0.356187807,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,23184,DB00682,10061599,41,19418,12,16352,0.000767992,2.87698444,1.482864952,6.01492101,0.004421035,DB0068210061599_,5.421381533,1.056742676,female,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,23185,DB08932,10061599,52,19391,9,6588,0.056398394,1.963039333,0.957834896,4.533533291,0.136806181,DB0893210061599_,1.989190089,0.674493952,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,23198,DB00246,10013968,44,1030,10,691,0.001041374,2.950283525,1.450602594,6.619345911,0.005698454,DB0024610013968_,5.167560334,1.081901276,female,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ziprasidone,DB00246
,23199,DB00734,10013968,72,3978,46,4856,0.000735435,1.910518021,1.298301116,2.836152204,0.004261192,DB0073410013968_,5.458206277,0.64737442,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,risperidone,DB00734
,23200,DB01224,10013968,163,7945,80,5837,0.00314454,1.496858749,1.135999027,1.985767377,0.01405835,DB0122410013968_,4.264538755,0.403368745,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,quetiapine,DB01224
,23203,DB00246,10016256,51,1023,21,680,0.084197242,1.613886227,0.943589605,2.851931389,0.185400394,DB0024610016256_,1.685237501,0.478645076,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ziprasidone,DB00246
,23204,DB00502,10016256,34,1360,30,1842,0.0973775,1.534765494,0.906576182,2.610403668,0.20692571,DB0050210016256_,1.575395437,0.428377597,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,haloperidol,DB00502
,23205,DB00734,10016256,113,3937,85,4817,0.000858223,1.626449838,1.212609503,2.188352246,0.004854922,DB0073410016256_,5.327762269,0.486399626,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,23206,DB01267,10016256,31,2821,44,3671,0.727201446,0.916823399,0.5581556,1.48938764,0.840566843,DB0126710016256_,0.173678801,-0.08684041,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,23207,DB14509,10016256,48,837,16,535,0.025319271,1.916762309,1.056465078,3.65505616,0.074197785,DB1450910016256_,2.601020977,0.650637465,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lithium carbonate,DB14509
,23215,DB00502,10039020,11,1383,46,1826,0.000221379,0.315830555,0.14694401,0.62182549,0.001569298,DB0050210039020_,6.45712658,-1.152549427,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,haloperidol,DB00502
,23216,DB00734,10039020,25,4025,64,4838,0.001202156,0.469573329,0.282761695,0.757845607,0.006413467,DB0073410039020_,5.049355319,-0.755930808,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,risperidone,DB00734
,23217,DB01224,10039020,43,8065,42,5875,0.187023484,0.745825385,0.475325063,1.170957412,0.332774567,DB0122410039020_,1.100289995,-0.293263774,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,quetiapine,DB01224
,23220,DB00502,10041349,31,1363,37,1835,0.622741167,1.127933065,0.672986558,1.878950361,0.762923745,DB0050210041349_,0.270597194,0.120386812,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,haloperidol,DB00502
,23221,DB00734,10041349,70,3980,82,4820,0.869595647,1.033837057,0.738427587,1.444137021,0.942026112,DB0073410041349_,0.059722285,0.033277179,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,23222,DB01224,10041349,169,7939,161,5756,0.015231327,0.761078128,0.607962452,0.953009272,0.049913406,DB0122410041349_,2.997465654,-0.273019262,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,23223,DB01267,10041349,32,2820,30,3685,0.199930959,1.393764796,0.818056819,2.380499663,0.348892285,DB0126710041349_,1.052992043,0.332008572,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,paliperidone,DB01267
,23232,DB00502,10049414,25,1369,34,1838,1,0.987198762,0.561809178,1.713175335,1,DB0050210049414_,0,-0.01288388,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,haloperidol,DB00502
,23233,DB00734,10049414,108,3942,157,4745,0.14955326,0.828043373,0.639580551,1.068821549,0.283346484,DB0073410049414_,1.261084806,-0.188689743,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,23234,DB01224,10049414,40,8068,41,5876,0.142184314,0.710574254,0.447343016,1.127837676,0.272836523,DB0122410049414_,1.298882479,-0.341681827,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,23240,DB00051,10017577,278,25453,92,11328,0.014773218,1.344885403,1.057573249,1.723271651,0.048725019,DB0005110017577_,3.021562644,0.296308807,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,23242,DB00051,10029223,35,25696,15,11405,1,1.035603841,0.550889652,2.041901797,1,DB0005110029223_,0,0.034984678,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,23243,DB00051,10033371,933,24798,270,11150,8.14313639768398e-11,1.553714885,1.352836704,1.789049647,2.68897412328045e-09,DB0005110033371_,19.73410608,0.440648764,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,23245,DB00060,10060800,46,9462,6,2459,0.122142778,1.992290648,0.847385285,5.714943506,0.244499498,DB0006010060800_,1.408542023,0.689285056,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,interferon beta-1a,DB00060
,23247,DB00005,10073317,2271,125811,1055,41364,2.87721410874192e-19,0.707733374,0.657033189,0.762696225,2.80621791644829e-17,DB0000510073317_,38.11210894,-0.345687846,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,23253,DB01175,10012735,611,10113,230,4662,0.010431992,1.224585218,1.046260574,1.437063923,0.036806029,DB0117510012735_,3.302093616,0.202602189,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,23255,DB00404,10013946,141,19751,38,9824,0.000576124,1.845553768,1.280727874,2.717318495,0.003473263,DB0040410013946_,5.662660707,0.612779378,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,23256,DB00996,10013946,166,38787,79,22346,0.183544002,1.210539134,0.92016815,1.6040563,0.328350514,DB0099610013946_,1.113673602,0.191065825,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,23257,DB01175,10013946,63,10661,13,4879,0.006203699,2.217744092,1.206708061,4.397247919,0.024305294,DB0117510013946_,3.717061073,0.796490505,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,23260,DB00996,10018867,41,38912,61,22364,2.37678229699383e-06,0.386300347,0.253405079,0.583534174,3.07752328455581e-05,DB0099610018867_,10.38880032,-0.951140111,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,23263,DB00404,10021036,48,19844,20,9842,0.606241465,1.190299442,0.692741565,2.118549511,0.749250372,DB0040410021036_,0.288682077,0.174204908,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,alprazolam,DB00404
,23264,DB01175,10021036,31,10693,22,4870,0.136757405,0.641770351,0.35938287,1.164621524,0.265152202,DB0117510021036_,1.327451272,-0.443524748,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,escitalopram,DB01175
,23270,DB00065,10028334,48,9416,30,4927,0.473725946,0.837234595,0.519035711,1.370387732,0.639640751,DB0006510028334_,0.446848587,-0.177650968,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,infliximab,DB00065
,23271,DB00169,10028334,821,37870,261,17914,1.15612932538425e-08,1.487979896,1.291420094,1.718980081,2.56771096896704e-07,DB0016910028334_,15.17508082,0.397419426,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,23272,DB01175,10028334,145,10579,41,4851,0.005329215,1.621655473,1.13743203,2.357319516,0.021524035,DB0117510028334_,3.838585068,0.483447524,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,23274,DB00169,10034960,59,38632,13,18162,0.011007043,2.133634764,1.156580755,4.241957487,0.038420869,DB0016910034960_,3.259154512,0.757826987,NA,10034960,Photophobia,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,23276,DB00996,10034960,48,38905,17,22408,0.093688454,1.626247261,0.918252036,3.017247535,0.20125044,DB0099610034960_,1.603205177,0.486275067,NA,10034960,Photophobia,10015919,Eye disorders,Eye,gabapentin,DB00996
,23278,DB00404,10040047,166,19726,85,9777,0.839953963,0.967986442,0.739997953,1.273938883,0.918069315,DB0040410040047_,0.085482385,-0.032537198,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,alprazolam,DB00404
,23279,DB01175,10040047,70,10654,64,4828,7.3251702323891e-05,0.495655713,0.347449715,0.708166468,0.000610017,DB0117510040047_,7.402024135,-0.701873721,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,escitalopram,DB01175
,23280,DB00065,10047700,130,9334,57,4900,0.278427451,1.197242178,0.868652964,1.668021591,0.442236393,DB0006510047700_,0.815910714,0.180020727,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,infliximab,DB00065
,23286,DB00169,10060795,180,38511,57,18118,0.009635063,1.485662924,1.096636847,2.039222725,0.034553192,DB0016910060795_,3.365255354,0.395861086,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,23287,DB00404,10060795,71,19821,17,9845,0.006121904,2.074389024,1.208251102,3.759244629,0.024055272,DB0040410060795_,3.727401079,0.729666664,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,alprazolam,DB00404
,23288,DB00996,10060795,119,38834,43,22382,0.008736053,1.595004803,1.116181729,2.317392136,0.031961466,DB0099610060795_,3.443224292,0.466876747,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,gabapentin,DB00996
,23289,DB01175,10060795,40,10684,18,4874,1,1.013774222,0.567297136,1.880711676,1,DB0117510060795_,0,0.01368022,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,escitalopram,DB01175
,23291,DB00404,10061225,40,19852,22,9840,0.687163921,0.901221213,0.522575702,1.59303287,0.811324139,DB0040410061225_,0.209087626,-0.104004533,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,23292,DB00996,10061225,107,38846,46,22379,0.109960279,1.340041648,0.939708541,1.937542522,0.226010203,DB0099610061225_,1.487175136,0.292700694,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,23295,DB00169,10061428,655,38036,358,17817,0.020798961,0.857046899,0.751346867,0.978835609,0.063742682,DB0016910061428_,2.752900896,-0.154262637,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,23296,DB00404,10061428,344,19548,148,9714,0.147752979,1.15501069,0.948337619,1.412332072,0.280887213,DB0040410061428_,1.269802067,0.144109599,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,alprazolam,DB00404
,23297,DB01175,10061428,178,10546,83,4809,0.892960669,0.977933516,0.747741808,1.287729755,0.955415161,DB0117510061428_,0.045609309,-0.02231359,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,escitalopram,DB01175
,23302,DB00188,10061818,41,7845,48,8780,0.915303557,0.955962209,0.613673556,1.483087477,0.962143444,DB0018810061818_,0.03859173,-0.045036897,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,23304,DB08908,10012601,43,10630,24,3255,0.020800946,0.54866175,0.325007221,0.946756824,0.063742682,DB0890810012601_,2.752900896,-0.600273148,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,dimethyl fumarate,DB08908
,23305,DB08908,10033371,263,10410,64,3215,0.098759086,1.269100003,0.959400593,1.700014316,0.208966196,DB0890810033371_,1.56558278,0.23830799,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,23315,DB08895,10005191,93,28021,23,6623,0.813567309,0.955706034,0.599726387,1.582534428,0.899877168,DB0889510005191_,0.105497005,-0.045304909,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,23316,DB01080,10025482,31,2028,33,2079,0.900406028,0.963017083,0.568055337,1.628824955,0.956698706,DB0108010025482_,0.044266769,-0.037684128,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,vigabatrin,DB01080
,23317,DB00186,10007776,41,16860,78,9930,4.06844380214756e-10,0.309599624,0.206578113,0.457948336,1.21246083151302e-08,DB0018610007776_,18.2280287,-1.172475351,male,10007776,Catatonia,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,23318,DB00334,10007776,32,2817,49,2763,0.05678824,0.640596389,0.395736712,1.024050426,0.13740313,DB0033410007776_,1.984836123,-0.445355678,NA,10007776,Catatonia,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,23322,DB00334,10010264,57,2792,76,2736,0.095134487,0.734999992,0.509854494,1.054535909,0.203409118,DB0033410010264_,1.592535968,-0.30788479,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,olanzapine,DB00334
,23323,DB00564,10010264,51,2553,21,1442,0.265008913,1.371617877,0.806681456,2.410956,0.42699355,DB0056410010264_,0.85098637,0.315990975,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,carbamazepine,DB00564
,23325,DB01068,10010264,285,13478,143,6697,0.917477761,0.99029034,0.805457303,1.2218859,0.963349796,DB0106810010264_,0.037338698,-0.009757107,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,23326,DB01238,10010264,134,5116,80,3422,0.438129342,1.120392604,0.840054896,1.502195061,0.60651638,DB0123810010264_,0.500023544,0.113679163,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,23330,DB01068,10035528,59,13704,45,6795,0.036245422,0.650100889,0.433151073,0.981676673,0.098025612,DB0106810035528_,2.322526488,-0.430627714,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,clonazepam,DB01068
,23332,DB00334,10053762,103,2746,122,2690,0.173768148,0.827074232,0.626454367,1.090197945,0.315860154,DB0033410053762_,1.152455714,-0.189860828,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,olanzapine,DB00334
,23333,DB00564,10053762,73,2531,53,1410,0.157483455,0.767385853,0.527992526,1.121559708,0.294172805,DB0056410053762_,1.223587912,-0.264765537,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,carbamazepine,DB00564
,23334,DB00915,10053762,38,1417,48,1003,0.01018855,0.56051483,0.353435225,0.883404343,0.036099754,DB0091510053762_,3.321469228,-0.578899579,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,amantadine,DB00915
,23335,DB00005,10040880,100,127982,40,42379,0.327928335,0.827810042,0.568247426,1.226541885,0.49644903,DB0000510040880_,0.70027446,-0.188971569,NA,10040880,Skin irritation,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,23337,DB00177,10000081,69,4731,39,2811,0.841684866,1.051214542,0.697722142,1.603857796,0.919292226,DB0017710000081_,0.084151225,0.049946202,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,valsartan,DB00177
,23338,DB00390,10000081,94,4051,34,3267,3.2454138137581e-05,2.229377668,1.486913151,3.414620237,0.000304229,DB0039010000081_,8.097731134,0.801722474,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,digoxin,DB00390
,23339,DB00820,10000081,264,11651,69,5747,1.1688479739876e-06,1.887204279,1.439922814,2.501862414,1.64382926678781e-05,DB0082010000081_,11.01589703,0.635096516,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,23340,DB01136,10000081,115,9769,119,10996,0.553534358,1.08775541,0.833174827,1.41969562,0.70708318,DB0113610000081_,0.346606968,0.084116316,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,23341,DB06616,10000081,48,913,35,768,0.573290317,1.153528948,0.722364758,1.858102265,0.723199001,DB0661610000081_,0.324070852,0.142825895,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,bosutinib,DB06616
,23342,DB13867,10000081,85,4465,26,2528,0.005125114,1.850831413,1.177162004,3.00103831,0.020866421,DB1386710000081_,3.869614078,0.615634951,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,fluticasone,DB13867
,23343,DB00820,10003549,550,11365,203,5613,0.000474322,1.338100222,1.133322771,1.584681568,0.002955795,DB0082010003549_,5.823987662,0.291250863,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,23344,DB06616,10003549,31,930,26,777,1,0.996155842,0.566909013,1.763044285,1,DB0661610003549_,0,-0.003851566,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,bosutinib,DB06616
,23345,DB00115,10006002,111,18314,38,10434,0.006117058,1.664177754,1.14092273,2.475203076,0.024039302,DB0011510006002_,3.728065198,0.50933116,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,23346,DB00158,10006002,66,16749,20,8084,0.082897182,1.59273642,0.952736371,2.775850019,0.183223158,DB0015810006002_,1.697050424,0.465453556,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,23349,DB00820,10006002,64,11851,20,5796,0.081393473,1.564996067,0.933664303,2.733207071,0.180702515,DB0082010006002_,1.710903161,0.447883311,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,23350,DB01136,10006002,42,9842,15,11100,5.15692880358148e-05,3.157732347,1.714346319,6.134171829,0.000453434,DB0113610006002_,7.698660191,1.149854158,female,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,carvedilol,DB01136
,23353,DB00115,10013082,59,18366,25,10447,0.255634294,1.342408686,0.827226916,2.23856774,0.416393842,DB0011510013082_,0.876123732,0.294465528,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,23354,DB00158,10013082,47,16768,23,8081,1,0.984806,0.585644768,1.700435552,1,DB0015810013082_,0,-0.015310611,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,23361,DB06616,10013968,54,907,40,763,0.595320947,1.135581128,0.731556005,1.775338811,0.740962241,DB0661610013968_,0.299805612,0.127144527,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosutinib,DB06616
,23362,DB13867,10013968,300,4250,136,2418,0.034614078,1.254952645,1.014862126,1.558099283,0.094660369,DB1386710013968_,2.357459854,0.227097839,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,23363,DB06616,10016256,112,849,102,701,0.510660414,0.906677281,0.674035228,1.220601874,0.671085118,DB0661610016256_,0.398859298,-0.097968702,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,bosutinib,DB06616
,23364,DB13867,10016256,318,4232,154,2400,0.123958297,1.171054784,0.956496837,1.438299304,0.247005068,DB1386710016256_,1.398346426,0.157904867,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,23365,DB00177,10019211,279,4521,69,2781,7.54057726239133e-13,2.48699149,1.895839904,3.300170346,3.43805851417096e-11,DB0017710019211_,24.0935291,0.911073743,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,valsartan,DB00177
,23366,DB00390,10019211,292,3853,75,3226,1.2560144676699e-22,3.259100756,2.509090047,4.277306806,1.66739092336886e-20,DB0039010019211_,45.54044178,1.181451316,female,10019211,Headache,10029205,Nervous system disorders,Nerv,digoxin,DB00390
,23367,DB00820,10019211,2124,9791,540,5276,6.92364808799322e-54,2.119426783,1.915970123,2.347260324,4.7891602629711e-51,DB0082010019211_,115.8654847,0.751145667,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,23368,DB01136,10019211,374,9510,213,10902,2.30253342677476e-16,2.012791088,1.692622765,2.398472116,1.65135310021213e-14,DB0113610019211_,31.73459629,0.69952236,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,23369,DB06616,10019211,57,904,31,772,0.048529526,1.569830005,0.985004272,2.543457576,0.122311868,DB0661610019211_,2.1011812,0.450967336,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,bosutinib,DB06616
,23370,DB01222,10039101,78,9196,36,5369,0.283567509,1.264989326,0.840569983,1.936301891,0.447957929,DB0122210039101_,0.803055959,0.235063684,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,23372,DB00316,10002383,43,65431,43,36910,0.009401136,0.564138387,0.360836626,0.881851181,0.033882927,DB0031610002383_,3.384844018,-0.572455691,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,23373,DB00331,10002383,36,24910,44,20708,0.092105137,0.680178041,0.425218576,1.081650475,0.198595916,DB0033110002383_,1.61648309,-0.38540069,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,metformin,DB00331
,23384,DB00722,10074903,147,25256,106,25926,0.0055261,1.423564792,1.100716377,1.846361854,0.022160889,DB0072210074903_,3.80942628,0.353164143,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,23391,DB08899,10003239,9,240,210,7923,0.308713785,1.414735454,0.630229561,2.783330854,0.476034641,DB0889910003239_,0.742264653,0.346942555,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,enzalutamide,DB08899
,23393,DB08899,10012735,12,237,348,7785,0.633489705,1.132674664,0.5713495,2.041995428,0.772036715,DB0889910012735_,0.258723172,0.124581795,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,enzalutamide,DB08899
,23399,DB08899,10047700,15,234,152,7981,0.000126544,3.364932077,1.809122265,5.841689933,0.000975714,DB0889910047700_,6.932341113,1.213407778,female,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,enzalutamide,DB08899
,23407,DB00051,10013710,35,25696,15,11405,1,1.035603841,0.550889652,2.041901797,1,DB0005110013710_,0,0.034984678,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,23412,DB00196,10030963,33,5050,17,3268,0.471871154,1.256141501,0.678587849,2.408703127,0.63802126,DB0019610030963_,0.449383673,0.228044722,NA,10030963,Oral candidiasis,10021881,Infections and infestations,Infec,fluconazole,DB00196
,23413,DB00316,10030963,62,65412,24,36929,0.117449611,1.458441362,0.897029725,2.443950657,0.237326921,DB0031610030963_,1.438316673,0.377368305,NA,10030963,Oral candidiasis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,23414,DB00635,10030963,43,33010,29,23765,0.812284141,1.067498412,0.651114137,1.773560084,0.899071824,DB0063510030963_,0.106392355,0.065317979,NA,10030963,Oral candidiasis,10021881,Infections and infestations,Infec,prednisone,DB00635
,23419,DB00051,10062355,164,25567,65,11355,0.472853015,1.120559933,0.83510932,1.518887462,0.638806646,DB0005110062355_,0.448153459,0.113828501,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,23422,DB00316,10062355,393,65081,245,36708,0.230439184,0.904762253,0.768943337,1.0661906,0.38644213,DB0031610062355_,0.950773151,-0.100083073,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,23423,DB00635,10062355,249,32804,117,23677,0.000101243,1.536065328,1.227403175,1.931478089,0.000806541,DB0063510062355_,7.122756086,0.429224165,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,23424,DB00836,10062355,45,5490,29,4046,0.637334021,1.143538126,0.700118412,1.894914087,0.774656066,DB0083610062355_,0.255336134,0.134127075,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,23426,DB08904,10062355,75,11535,15,3544,0.135690604,1.53612281,0.873280545,2.883878724,0.26365927,DB0890410062355_,1.333097652,0.429261586,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,23428,DB00203,10025082,169,13709,79,8859,0.018429529,1.382396081,1.050718055,1.831865354,0.0579206,DB0020310025082_,2.848682178,0.323818284,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,23429,DB00559,10025082,108,9551,44,3262,0.349017148,0.838294388,0.583832461,1.221890232,0.518549345,DB0055910025082_,0.656720087,-0.176385942,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,23457,DB14500,10035226,89,7720,65,4008,0.040243878,0.710858232,0.509295006,0.996780481,0.106141916,DB1450010035226_,2.242978249,-0.341282262,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,potassium,DB14500
,23465,DB00193,10013754,110,19210,38,8664,0.181281468,1.305514939,0.894528755,1.942808805,0.325477007,DB0019310013754_,1.12246346,0.266597552,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,23466,DB00497,10013754,196,19071,202,16173,0.054654123,0.822859301,0.671771095,1.007726037,0.133741434,DB0049710013754_,2.011846937,-0.194970051,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,23468,DB00193,10016322,349,18971,89,8613,5.12341154894578e-07,1.780293675,1.404762862,2.276082296,7.92596683872182e-06,DB0019310016322_,11.74536625,0.576778336,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,23469,DB00788,10016322,159,9197,47,5014,0.000163055,1.844253153,1.321771205,2.616216196,0.001211047,DB0078810016322_,6.716269656,0.6120744,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,23473,DB00497,10047513,115,19152,90,16285,0.574543375,1.086526677,0.816712032,1.44918675,0.724293069,DB0049710047513_,0.322559178,0.082986074,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,oxycodone,DB00497
,23474,DB00788,10047895,182,9174,109,4952,0.419950343,0.901304008,0.705091284,1.156569011,0.58887142,DB0078810047895_,0.529547422,-0.103912666,NA,10047895,Weight decreased,10022891,Investigations,Inv,naproxen,DB00788
,23475,DB00193,10055798,60,19260,33,8669,0.369707173,0.818397712,0.526116964,1.293251361,0.539311264,DB0019310055798_,0.61746239,-0.200406859,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,tramadol,DB00193
,23476,DB00497,10055798,50,19217,60,16315,0.084139223,0.707502942,0.475863754,1.047886559,0.185311448,DB0049710055798_,1.685717366,-0.346013492,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,oxycodone,DB00497
,23477,DB00497,10062355,178,19089,120,16255,0.053928696,1.263104361,0.995466986,1.607306516,0.132367887,DB0049710062355_,2.022170208,0.23357247,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,23478,DB00788,10062355,44,9312,27,5034,0.619162886,0.880978435,0.532824714,1.481468412,0.759996182,DB0078810062355_,0.27444187,-0.126722131,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,23479,DB00046,10007559,74,5385,83,4609,0.106408534,0.763112915,0.548746367,1.059541366,0.220748799,DB0004610007559_,1.510729878,-0.27034927,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,insulin lispro,DB00046
,23480,DB00046,10035598,30,5429,28,4664,0.792473951,0.920463792,0.530565567,1.601484062,0.887531177,DB0004610035598_,0.119311629,-0.082877614,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin lispro,DB00046
,23482,DB00454,10008531,14,1953,37,564,8.08385208551503e-14,0.109392948,0.054221102,0.20891791,4.19928956655657e-12,DB0045410008531_,26.19610576,-2.212808849,male,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,meperidine,DB00454
,23487,DB00338,10003658,336,33338,302,21970,0.00010922,0.733218753,0.625171725,0.860184225,0.000860053,DB0033810003658_,7.058516983,-0.310311186,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,omeprazole,DB00338
,23488,DB00381,10003658,293,29067,278,22609,0.019617468,0.819799418,0.692675384,0.970412439,0.060879,DB0038110003658_,2.798866985,-0.19869558,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,amlodipine,DB00381
,23489,DB00590,10003658,10,766,46,1906,0.09838484,0.541029557,0.242168203,1.093954685,0.208467998,DB0059010003658_,1.567969736,-0.614281367,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,doxazosin,DB00590
,23491,DB00682,10003658,489,18970,383,15981,0.301931855,1.075612668,0.937442666,1.234832366,0.468278285,DB0068210003658_,0.758692534,0.072890423,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,warfarin,DB00682
,23492,DB00736,10003658,88,10503,64,5489,0.048424677,0.718577941,0.513973361,1.009427198,0.122130363,DB0073610003658_,2.102666253,-0.330481102,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,esomeprazole,DB00736
,23493,DB09153,10003658,67,7732,94,5605,3.75679354603308e-05,0.516727536,0.371242101,0.715868926,0.000345936,DB0915310003658_,7.969257914,-0.660239553,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,sodium chloride,DB09153
,23494,DB00215,10003988,199,10904,60,5216,0.001580012,1.586508219,1.180748661,2.15863341,0.008017491,DB0021510003988_,4.826129724,0.461535513,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,23495,DB00437,10003988,131,6790,178,11368,0.075448083,1.232126222,0.973639152,1.556016069,0.170557115,DB0043710003988_,1.768685051,0.208741313,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,allopurinol,DB00437
,23496,DB00524,10003988,49,1528,14,1330,0.000100611,3.045238307,1.645474724,6.000904381,0.000801991,DB0052410003988_,7.128413777,1.11357916,female,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,metolazone,DB00524
,23498,DB00641,10003988,286,13838,185,12290,0.000923333,1.372987836,1.13533394,1.663748987,0.005158852,DB0064110003988_,5.267041218,0.316989267,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,23500,DB00682,10003988,384,19075,212,16152,4.89665345303765e-07,1.533736874,1.291801707,1.824938786,7.61363714954716e-06,DB0068210003988_,11.78556956,0.427707159,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,23501,DB00736,10003988,221,10370,91,5462,0.05398409,1.279171573,0.995315814,1.655113894,0.132453263,DB0073610003988_,2.021525427,0.24621266,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,23502,DB01012,10003988,36,10596,24,8661,0.516201835,1.226062227,0.710951625,2.14987169,0.675917368,DB0101210003988_,0.391684447,0.203807592,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cinacalcet,DB01012
,23503,DB01136,10003988,227,9657,149,10966,2.11863771857707e-07,1.729933686,1.398136863,2.145624617,3.57435124729129e-06,DB0113610003988_,12.54172687,0.548083076,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,carvedilol,DB01136
,23504,DB09153,10003988,124,7675,59,5640,0.006528247,1.544387967,1.121595067,2.147257929,0.02532767,DB0915310003988_,3.675857808,0.434627694,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium chloride,DB09153
,23505,DB00437,10006093,15,6906,55,11491,0.006064802,0.453813165,0.23789207,0.815471176,0.023871417,DB0043710006093_,3.735073459,-0.790069697,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,allopurinol,DB00437
,23512,DB00215,10007617,254,10849,149,5127,0.040289768,0.805634893,0.653646123,0.995737716,0.106225693,DB0021510007617_,2.242189268,-0.216124625,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,citalopram,DB00215
,23513,DB00338,10007617,74,33600,60,22212,0.251229576,0.815331329,0.571915774,1.166397039,0.411181158,DB0033810007617_,0.888721388,-0.20416071,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,omeprazole,DB00338
,23514,DB00381,10007617,124,29236,109,22778,0.389718516,0.886327924,0.679225024,1.157914809,0.559614924,DB0038110007617_,0.580506367,-0.120668279,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,amlodipine,DB00381
,23515,DB00437,10007617,21,6900,30,11516,0.664207599,1.168272541,0.635167426,2.111499013,0.795547914,DB0043710007617_,0.228724202,0.155526197,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,allopurinol,DB00437
,23518,DB00641,10007617,37,14087,42,12433,0.309604473,0.777527753,0.485644243,1.240197402,0.477047515,DB0064110007617_,0.74013918,-0.251635941,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,simvastatin,DB00641
,23520,DB00682,10007617,50,19409,49,16315,0.479966953,0.857749597,0.566382344,1.29961279,0.644804956,DB0068210007617_,0.438807402,-0.153443068,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,warfarin,DB00682
,23523,DB01136,10007617,21,9863,83,11032,1.59422537123271e-08,0.283028189,0.166356751,0.461620131,3.41371910642455e-07,DB0113610007617_,14.89029331,-1.26220878,male,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,carvedilol,DB01136
,23524,DB09153,10007617,21,7778,36,5663,0.001775132,0.424737183,0.235320346,0.748412259,0.008816127,DB0915310007617_,4.731172594,-0.856284695,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,sodium chloride,DB09153
,23525,DB00215,10013968,411,10692,144,5132,0.00120202,1.369942104,1.126925114,1.67296763,0.006413467,DB0021510013968_,5.049355319,0.314768479,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,23526,DB00590,10013968,41,735,79,1873,0.178066205,1.322411381,0.87514857,1.973005232,0.321394645,DB0059010013968_,1.135085488,0.279456874,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxazosin,DB00590
,23527,DB00658,10013968,61,1242,61,1335,0.711601839,1.074826369,0.734640411,1.57261596,0.828143733,DB0065810013968_,0.188568549,0.072159131,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sevelamer,DB00658
,23528,DB00736,10013968,494,10097,234,5319,0.201414704,1.112119623,0.946496777,1.309574923,0.350736063,DB0073610013968_,1.047721297,0.106267765,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,23529,DB00437,10019211,255,6666,219,11327,3.42293188119312e-13,1.978513244,1.640787028,2.387125396,1.63288138833323e-11,DB0043710019211_,24.83808985,0.682345676,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,23530,DB00524,10019211,136,1441,53,1291,2.22106186233784e-07,2.298161048,1.64565768,3.248964206,3.72562929492982e-06,DB0052410019211_,12.50027478,0.832109259,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,metolazone,DB00524
,23531,DB00590,10019211,34,742,39,1913,0.000892969,2.246904236,1.364448405,3.684157753,0.005019087,DB0059010019211_,5.29450727,0.809553374,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,doxazosin,DB00590
,23532,DB00658,10019211,37,1266,23,1373,0.03720419,1.744288055,1.003081154,3.093242178,0.099960353,DB0065810019211_,2.302981641,0.556346481,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sevelamer,DB00658
,23533,DB00736,10019211,546,10045,168,5385,1.59241158811768e-10,1.742228693,1.45806815,2.090441678,5.02781244368446e-09,DB0073610019211_,19.10828085,0.555165152,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,23534,DB01012,10019211,107,10525,62,8623,0.029844225,1.413904165,1.02320725,1.968414661,0.084377267,DB0101210019211_,2.472457263,0.346354789,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cinacalcet,DB01012
,23535,DB09153,10019211,516,7283,195,5504,5.76316422135667e-17,1.999660952,1.686131138,2.379059887,4.39723574915414e-15,DB0915310019211_,33.05780029,0.692977642,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,23536,DB00215,10025482,321,10782,79,5197,2.65724359175997e-08,1.958463852,1.523051541,2.543656216,5.42701226180348e-07,DB0021510025482_,14.4267069,0.672160417,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,23537,DB00338,10025482,1118,32556,482,21790,3.34552219047305e-16,1.552448247,1.39198225,1.733428378,2.36389921442431e-14,DB0033810025482_,31.37587884,0.439833199,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,23538,DB00437,10025482,204,6717,217,11329,4.18248514181877e-06,1.585465641,1.300047234,1.933205162,5.0479346327209e-05,DB0043710025482_,9.893946289,0.460878144,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,23539,DB00524,10025482,85,1492,40,1304,0.001280978,1.85685479,1.250702783,2.797207058,0.006745568,DB0052410025482_,4.998869519,0.618884083,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,23540,DB00590,10025482,26,750,31,1921,0.006866512,2.147579292,1.215786175,3.765737974,0.026402373,DB0059010025482_,3.634301368,0.764341297,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,doxazosin,DB00590
,23541,DB00658,10025482,38,1265,24,1372,0.040128935,1.716903353,0.997184083,3.010383686,0.105929104,DB0065810025482_,2.244985239,0.540522292,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sevelamer,DB00658
,23542,DB00682,10025482,986,18473,344,16020,7.17093454432876e-52,2.485483552,2.19205731,2.823599888,4.54187986741401e-49,DB0068210025482_,111.3133286,0.910467229,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,23543,DB00736,10025482,365,10226,103,5450,3.4776697193726e-09,1.888559561,1.509668494,2.379725015,8.64811244784379e-08,DB0073610025482_,16.26333966,0.635814402,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,23544,DB01012,10025482,435,10197,239,8446,4.22045401330767e-07,1.507508812,1.280974639,1.777399461,6.63484651553781e-06,DB0101210025482_,11.92317502,0.410458495,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,23545,DB01136,10025482,292,9592,236,10879,0.000142005,1.403266906,1.17532324,1.6768342,0.001076455,DB0113610025482_,6.834081984,0.338803022,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,23546,DB09153,10025482,176,7623,92,5607,0.008616964,1.407078526,1.084614647,1.835504825,0.031610501,DB0915310025482_,3.454265914,0.341515587,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,23547,DB00590,10028813,45,731,68,1884,0.007661377,1.705163476,1.131775124,2.548343993,0.028770526,DB0059010028813_,3.548403803,0.533660986,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,doxazosin,DB00590
,23548,DB00658,10028813,105,1198,62,1334,0.000113694,1.885344539,1.350449348,2.650394028,0.000890876,DB0065810028813_,7.023305344,0.634110584,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sevelamer,DB00658
,23549,DB09153,10028813,441,7358,199,5500,3.93144987507344e-09,1.656425937,1.392684101,1.975466359,9.65825065159413e-08,DB0915310028813_,16.1528682,0.504662231,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,23550,DB00215,10028836,72,11031,15,5261,0.002548688,2.289159967,1.298554652,4.304343941,0.011838179,DB0021510028836_,4.436425477,0.828184924,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,23551,DB00338,10028836,172,33502,72,22200,0.001009193,1.582975968,1.19486037,2.115692537,0.005546608,DB0033810028836_,5.194568778,0.459306599,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,23552,DB00437,10028836,22,6899,31,11515,0.571025283,1.184490029,0.652899423,2.114800156,0.72141499,DB0043710028836_,0.326540732,0.169312327,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,allopurinol,DB00437
,23555,DB00641,10028836,65,14059,47,12428,0.298728993,1.222527467,0.826441846,1.820495593,0.464720053,DB0064110028836_,0.766320092,0.20092041,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,23557,DB00682,10028836,98,19361,46,16318,0.001012401,1.795557786,1.251714004,2.608961032,0.00556075,DB0068210028836_,5.19202226,0.585315718,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,23558,DB00736,10028836,70,10521,22,5531,0.036198616,1.672666118,1.022056095,2.840219286,0.097934292,DB0073610028836_,2.323458515,0.514418831,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,23560,DB01136,10028836,35,9849,30,11085,0.319571097,1.313053858,0.782511175,2.215820393,0.487772272,DB0113610028836_,0.717906638,0.272355613,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,carvedilol,DB01136
,23562,DB00215,10035664,269,10834,149,5127,0.137561022,0.854378311,0.694810259,1.053814236,0.266287989,DB0021510035664_,1.323176891,-0.157381196,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,citalopram,DB00215
,23563,DB00437,10035664,368,6553,609,10937,0.918865454,1.008530651,0.880460296,1.154039321,0.964166805,DB0043710035664_,0.036490966,0.00849447,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,allopurinol,DB00437
,23564,DB00524,10035664,126,1451,63,1281,0.000281383,1.76533865,1.281625885,2.451781607,0.001916845,DB0052410035664_,6.257074518,0.568342542,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,metolazone,DB00524
,23565,DB00590,10035664,24,752,81,1871,0.225104978,0.737301271,0.443400561,1.185642298,0.379969455,DB0059010035664_,0.967664412,-0.30475869,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,doxazosin,DB00590
,23566,DB00658,10035664,62,1241,63,1333,0.783876493,1.057090408,0.725665404,1.539304727,0.882368791,DB0065810035664_,0.12514518,0.055520236,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sevelamer,DB00658
,23567,DB01136,10035664,419,9465,432,10683,0.206916371,1.094714369,0.951982745,1.258753481,0.35754831,DB0113610035664_,1.028484792,0.090493479,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,carvedilol,DB01136
,23568,DB09153,10035664,337,7462,311,5388,0.002540179,0.782445326,0.665954361,0.919491435,0.011806463,DB0915310035664_,4.439108179,-0.245331229,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,23569,DB00215,10045555,53,11050,22,5254,0.710348701,1.145445613,0.683972492,1.980054949,0.827231264,DB0021510045555_,0.189670981,0.135793743,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,23570,DB00338,10045555,62,33612,82,22190,3.69841383609514e-05,0.499158601,0.352832715,0.703106444,0.000340858,DB0033810045555_,7.984043498,-0.694831397,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,23571,DB00381,10045555,85,29275,64,22823,0.868881696,1.035419731,0.739428012,1.456073003,0.941621365,DB0038110045555_,0.060152033,0.034806881,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,23575,DB00641,10045555,48,14076,34,12441,0.375488255,1.247769162,0.787007787,1.998273615,0.545332971,DB0064110045555_,0.606358714,0.221357286,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,23577,DB00682,10045555,65,19394,56,16308,0.927283097,0.976014054,0.671754205,1.422065124,0.969361391,DB0068210045555_,0.031117784,-0.024278293,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,23580,DB01136,10045555,66,9818,44,11071,0.007165623,1.691374421,1.13652206,2.538839657,0.027290938,DB0113610045555_,3.601200574,0.525541465,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,23581,DB09153,10045555,31,7768,43,5656,0.006436614,0.524956989,0.319338569,0.853838559,0.025036832,DB0915310045555_,3.687407262,-0.644438946,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,23582,DB00524,10047700,74,1503,34,1310,0.002176227,1.896587064,1.23814454,2.957167335,0.010430451,DB0052410047700_,4.563025754,0.640055989,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,metolazone,DB00524
,23583,DB00590,10047700,26,750,41,1911,0.073522145,1.615495027,0.941539095,2.726720131,0.167391298,DB0059010047700_,1.787421104,0.479641428,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,doxazosin,DB00590
,23584,DB00658,10047700,69,1234,54,1342,0.07968115,1.389430799,0.950480428,2.040001097,0.177886902,DB0065810047700_,1.726607314,0.328894166,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sevelamer,DB00658
,23585,DB00736,10047700,404,10187,129,5424,3.0396652955439e-07,1.6674476,1.36034182,2.054834944,4.945688783248e-06,DB0073610047700_,12.21699431,0.511294074,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,23586,DB01012,10047700,349,10283,265,8420,0.364827598,1.078400979,0.914132396,1.273317536,0.534401384,DB0101210047700_,0.626608066,0.075479369,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cinacalcet,DB01012
,23587,DB09153,10047700,311,7488,155,5544,5.91856573454317e-05,1.485501604,1.21720518,1.8188843,0.000510064,DB0915310047700_,7.580974476,0.395752496,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,23588,DB00215,10068319,53,11050,13,5263,0.033835346,1.94172711,1.043078995,3.886453647,0.093039237,DB0021510068319_,2.374733977,0.66357784,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,23589,DB00437,10068319,50,6871,51,11495,0.013409188,1.640053578,1.086509067,2.474722594,0.044971037,DB0043710068319_,3.101736629,0.494728911,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,23592,DB00641,10068319,100,14024,51,12424,0.001351146,1.737037105,1.226620095,2.486298308,0.007055701,DB0064110068319_,4.953919332,0.552180849,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,23594,DB00682,10068319,190,19269,50,16314,9.52496555705214e-16,3.217023983,2.343159408,4.489227039,6.37869349470358e-14,DB0068210068319_,30.38322801,1.168456703,female,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,23595,DB00736,10068319,85,10506,19,5534,0.000379562,2.356390273,1.418706905,4.109171272,0.002455825,DB0073610068319_,6.009292365,0.857130903,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,23597,DB01136,10068319,44,9840,30,11085,0.035636219,1.652179665,1.014656038,2.724321238,0.096761326,DB0113610068319_,2.335507884,0.502095425,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,23598,DB09153,10068319,52,7747,16,5683,0.001871746,2.383952145,1.338131766,4.478097384,0.009217581,DB0915310068319_,4.686642641,0.868759676,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,23599,DB00005,10017944,414,127668,110,42309,0.042782628,1.24725445,1.008145481,1.553999206,0.111278746,DB0000510017944_,2.195716997,0.220944695,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,23601,DB01050,10028372,159,17949,70,9301,0.263794383,1.177007392,0.882127682,1.584182734,0.425636743,DB0105010028372_,0.854169013,0.162975108,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,23605,DB00005,10018870,74,128008,26,42393,0.817040757,0.94256908,0.595581893,1.535895702,0.902121998,DB0000510018870_,0.103005515,-0.059146068,NA,10018870,Blood urine present,10022891,Investigations,Inv,etanercept,DB00005
,23606,DB01050,10002198,81,18027,22,9349,0.006480929,1.90939059,1.179010552,3.215445251,0.025183119,DB0105010002198_,3.681581385,0.646784128,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,ibuprofen,DB01050
,23607,DB01050,10015967,35,18073,19,9352,0.886160566,0.953212299,0.530197403,1.764978208,0.952648431,DB0105010015967_,0.048509351,-0.047917631,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,ibuprofen,DB01050
,23608,DB01050,10024570,41,18067,25,9346,0.517734404,0.848381256,0.503388314,1.456705205,0.677263695,DB0105010024570_,0.389694576,-0.16442515,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,23609,DB01050,10042682,83,18025,38,9333,0.565296652,1.130929476,0.760917868,1.708342184,0.716865154,DB0105010042682_,0.332867525,0.123039839,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,23610,DB08896,10012735,130,693,138,902,0.126680468,1.225990401,0.937719399,1.60231473,0.251022085,DB0889610012735_,1.382214357,0.203749008,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,regorafenib,DB08896
,23611,DB08896,10042128,38,785,38,1002,0.345529509,1.276255313,0.784091095,2.077324993,0.51493937,DB0889610042128_,0.663706113,0.243930253,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,regorafenib,DB08896
,23612,DB08895,10038428,64,28050,22,6624,0.131248353,0.686990154,0.417103219,1.172285683,0.257549275,DB0889510038428_,1.356544217,-0.375435318,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,tofacitinib,DB08895
,23613,DB00331,10048858,22,24924,38,20714,0.006137371,0.481158796,0.270976421,0.834833269,0.024093914,DB0033110048858_,3.725796005,-0.731557926,NA,10048858,Ischaemic cardiomyopathy,10007541,Cardiac disorders,Card,metformin,DB00331
,23614,DB00115,10007515,58,18367,43,10429,0.213085503,0.76591114,0.507013007,1.1649266,0.365144563,DB0011510007515_,1.007461942,-0.266689121,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,cyanocobalamin,DB00115
,23615,DB00115,10007559,142,18283,109,10363,0.020797427,0.738443946,0.570559729,0.957829801,0.063742682,DB0011510007559_,2.752900896,-0.303210082,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,cyanocobalamin,DB00115
,23617,DB00115,10028596,87,18338,103,10369,4.50093758611517e-07,0.477606587,0.354469544,0.642282027,7.05468959159435e-06,DB0011510028596_,11.86181797,-0.738967925,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,cyanocobalamin,DB00115
,23618,DB00722,10038695,139,25264,194,25838,0.005894757,0.732780611,0.584652221,0.916450434,0.023345439,DB0072210038695_,3.757353649,-0.310908925,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,23624,DB00363,10035669,32,4596,56,6832,0.513242623,0.849468881,0.531421443,1.33691257,0.673249107,DB0036310035669_,0.395639874,-0.163143971,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,clozapine,DB00363
,23625,DB00734,10035669,20,4030,31,4871,0.401522837,0.779818886,0.420561357,1.414901827,0.571306346,DB0073410035669_,0.559829706,-0.248693583,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,risperidone,DB00734
,23627,DB00175,10028735,72,8059,17,6089,2.59541853353385e-06,3.199702413,1.864348832,5.7974057,3.32864484771589e-05,DB0017510028735_,10.3103602,1.16305781,female,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,23630,DB00668,10028735,39,10052,16,4287,1,1.039522446,0.566979879,1.994833846,1,DB0066810028735_,0,0.038761421,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,23631,DB00678,10028735,122,15477,36,10688,2.84125710911632e-06,2.340191078,1.600431959,3.497920733,3.61221006593095e-05,DB0067810028735_,10.22860567,0.850232583,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,23633,DB00999,10028735,107,21323,31,12208,0.000513413,1.976104609,1.313276038,3.052473837,0.003154737,DB0099910028735_,5.758850047,0.681127538,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,23635,DB01075,10028735,102,19846,37,11060,0.026311214,1.536295885,1.044339028,2.304574022,0.07644838,DB0107510028735_,2.571139544,0.42937425,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,23637,DB09153,10028735,46,7753,24,5675,0.184536718,1.402916102,0.837646049,2.40607982,0.329599269,DB0915310028735_,1.109877699,0.338553001,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,23656,DB00060,10042609,47,9461,7,2458,0.235639724,1.744297784,0.782216865,4.579309023,0.392795139,DB0006010042609_,0.934467078,0.556352058,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,interferon beta-1a,DB00060
,23657,DB00425,10016173,410,12285,212,7272,0.118850081,1.144813686,0.964947313,1.361163338,0.239513485,DB0042510016173_,1.429145557,0.135241904,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,23658,DB00425,10024855,109,12586,64,7420,1,1.004066847,0.729705651,1.391326273,1,DB0042510024855_,0,0.0040586,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,23659,DB00425,10045555,60,12635,20,7464,0.027130097,1.772172392,1.052106786,3.106865551,0.078295411,DB0042510045555_,2.547266288,0.572206134,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,23663,DB00433,10013700,343,7313,63,5957,2.28574875610205e-35,4.434432847,3.373444859,5.910918492,7.06834188872264e-33,DB0043310013700_,74.02968214,1.489399726,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,prochlorperazine,DB00433
,23665,DB08868,10013700,43,9159,7,2504,0.229748985,1.679316065,0.747788864,4.430545238,0.385641436,DB0886810013700_,0.952847264,0.518386606,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,fingolimod,DB08868
,23666,DB00811,10003549,112,2686,118,4038,0.009241575,1.426801817,1.0865481,1.87270037,0.033415614,DB0081110003549_,3.398732005,0.355435448,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,23667,DB08934,10003549,90,4399,75,6129,0.001091105,1.671803818,1.213731224,2.308373155,0.005917002,DB0893410003549_,5.129925432,0.513903174,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,23672,DB01076,10067585,43,25704,43,25540,1,0.993619475,0.63549012,1.553493244,1,DB0107610067585_,0,-0.006400967,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,23675,DB00103,10033371,14,380,52,606,0.005426731,0.429659739,0.216801721,0.800024812,0.021834018,DB0010310033371_,3.824286087,-0.844761688,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,agalsidase beta,DB00103
,23677,DB00924,10033371,596,9566,137,4114,9.50996218002154e-12,1.870867022,1.545355634,2.277707671,3.64652597960417e-10,DB0092410033371_,21.732076,0.626401972,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,23678,DB00103,10037660,18,376,61,597,0.005202896,0.468828366,0.256588751,0.818930285,0.021122577,DB0010310037660_,3.857412819,-0.757518535,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,agalsidase beta,DB00103
,23680,DB00924,10037660,187,9975,82,4169,0.73585719,0.953119106,0.729401419,1.254512307,0.847406972,DB0092410037660_,0.165574213,-0.048015403,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,23685,DB06285,10022061,149,8701,12,1094,0.163247918,1.561120646,0.863831673,3.0999395,0.301745475,DB0628510022061_,1.198171416,0.445403926,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,23687,DB06285,10022067,94,8756,7,1099,0.204784285,1.685399248,0.783880803,4.317215843,0.354816453,DB0628510022067_,1.036154658,0.522002478,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,23696,DB00005,10000496,197,127885,78,42341,0.18485963,0.836180071,0.640047147,1.101598556,0.329982384,DB0000510000496_,1.108716009,-0.178911294,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,23697,DB00005,10013082,374,127708,119,42300,0.754280709,1.041015554,0.844485907,1.290889417,0.861880515,DB0000510013082_,0.148638631,0.040196731,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,23699,DB06228,10017788,29,15883,187,15889,1.61712351063936e-29,0.155148849,0.101051265,0.230404562,3.48410585878325e-27,DB0622810017788_,60.92158607,-1.863370309,male,10017788,Gastric haemorrhage,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,23701,DB00169,10046306,318,38373,112,18063,0.008067324,1.336551069,1.073477965,1.674146496,0.029992678,DB0016910046306_,3.50680201,0.290092467,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,23703,DB00316,10046306,536,64938,186,36767,3.72156627091349e-09,1.631582297,1.377681401,1.939221292,9.17218653829922e-08,DB0031610046306_,16.20450504,0.489550279,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,23704,DB00437,10046306,37,6884,56,11490,0.668103847,1.102782067,0.706943537,1.702296404,0.798377415,DB0043710046306_,0.225173842,0.097836139,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,allopurinol,DB00437
,23705,DB00451,10046306,368,46903,72,15347,3.67824686440702e-05,1.672315493,1.295067916,2.185533489,0.000339416,DB0045110046306_,7.988283328,0.514209189,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,23706,DB00668,10046306,285,9806,96,4207,0.046967792,1.273608878,1.004199418,1.626954348,0.119389625,DB0066810046306_,2.125362977,0.241854507,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,epinephrine,DB00668
,23707,DB00682,10046306,144,19315,61,16303,4.07102132754697e-06,1.992460157,1.465999295,2.73617836,4.93118873707705e-05,DB0068210046306_,9.917345383,0.689370135,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,23708,DB00722,10046306,142,25261,85,25947,7.96852024878187e-05,1.715925736,1.30160232,2.273654012,0.000656797,DB0072210046306_,7.328135608,0.539952723,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,lisinopril,DB00722
,23709,DB01076,10046306,152,25595,100,25483,0.001253084,1.513328552,1.167357876,1.969109609,0.006624559,DB0107610046306_,5.016971408,0.414311564,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,23711,DB01373,10046306,155,22565,36,7345,0.076007951,1.401438398,0.968894703,2.076210917,0.171490902,DB0137310046306_,1.763225066,0.337499137,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,calcium,DB01373
,23713,DB09153,10046306,145,7654,78,5621,0.028617454,1.365175135,1.027334311,1.825588705,0.081650994,DB0915310046306_,2.505301283,0.311282725,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,23717,DB08934,10013709,142,4347,413,5791,1.68932264076758e-16,0.458077569,0.374303408,0.557995433,1.2317294205985e-14,DB0893410013709_,32.02777209,-0.780716744,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,23719,DB00005,10020096,393,127689,159,42260,0.034013704,0.818018076,0.678468609,0.99014429,0.093431937,DB0000510020096_,2.370522056,-0.200870845,NA,10020096,Hip arthroplasty,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,23720,DB05259,10010305,39,11231,14,2714,0.222293865,0.673197153,0.356965977,1.344296805,0.376396704,DB0525910010305_,0.977111628,-0.395717045,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,glatiramer,DB05259
,23721,DB00295,10027175,99,14564,55,9547,0.363343247,1.179893853,0.839297594,1.673661479,0.532861533,DB0029510027175_,0.629493677,0.16542448,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,morphine,DB00295
,23722,DB00497,10027175,190,19077,101,16274,0.00011653,1.604758155,1.252938561,2.06558661,0.000909762,DB0049710027175_,7.002327396,0.472973063,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,23723,DB00829,10027175,115,7937,45,4409,0.046431651,1.419572182,0.995401117,2.055019492,0.118370199,DB0082910027175_,2.133938286,0.350355546,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,23724,DB05259,10027175,233,11037,49,2679,0.403639007,1.154188939,0.842379692,1.609289285,0.573344154,DB0525910027175_,0.556269124,0.14339788,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,23725,DB00295,10033295,187,14476,153,9449,0.044225517,0.797804224,0.63978002,0.996027808,0.114034503,DB0029510033295_,2.171254221,-0.225892045,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,23726,DB00829,10033295,125,7927,124,4330,4.70840973917371e-06,0.550645622,0.424837158,0.713836498,5.61272335574517e-05,DB0082910033295_,9.787889417,-0.59666383,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,23729,DB00331,10033295,116,24830,209,20543,7.77312845078763e-12,0.459201174,0.362468164,0.579387208,3.02020223693943e-10,DB0033110033295_,21.92052713,-0.778266877,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,23730,DB00641,10033295,63,14061,54,12421,0.926119342,1.030596683,0.704473684,1.512123067,0.968569089,DB0064110033295_,0.031935463,0.030137939,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,23731,DB00331,10042464,44,24902,78,20674,5.15709269345486e-05,0.468330121,0.315863257,0.686618339,0.000453434,DB0033110042464_,7.698660191,-0.758581845,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,metformin,DB00331
,23732,DB00381,10042464,68,29292,143,22744,2.40570108598464e-12,0.369230583,0.272314328,0.496455684,1.01825850314181e-10,DB0038110042464_,23.00775711,-0.996333945,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,23734,DB00722,10042464,36,25367,61,25971,0.018955941,0.604225133,0.388547822,0.927372295,0.059231683,DB0072210042464_,2.826298702,-0.503808414,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,23735,DB00193,10025482,574,18746,139,8563,2.38207288297341e-12,1.886277916,1.561753771,2.291112246,1.00988364078961e-10,DB0019310025482_,23.01601581,0.634605531,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,23736,DB09072,10025482,212,6259,56,2479,0.007064533,1.49938331,1.10763704,2.058294613,0.026974325,DB0907210025482_,3.612869787,0.405053897,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,23740,DB06366,10011906,52,1686,7,76,0.015763814,0.335180529,0.145041836,0.903997848,0.051255797,DB0636610011906_,2.970926557,-1.093086,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pertuzumab,DB06366
,23742,DB00761,10024690,36,15271,17,8608,0.66772572,1.193642815,0.652896883,2.267791222,0.798169392,DB0076110024690_,0.225434433,0.17700982,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,potassium chloride,DB00761
,23749,DB00335,10003658,88,8378,84,5381,0.011707239,0.672901148,0.492267589,0.9203393,0.040365289,DB0033510003658_,3.209785048,-0.396156842,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,atenolol,DB00335
,23750,DB00404,10003658,128,19764,75,9787,0.261848243,0.845145948,0.629947451,1.140630611,0.423516535,DB0040410003658_,0.859162723,-0.168245947,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,alprazolam,DB00404
,23752,DB00390,10007515,81,4064,72,3229,0.511267641,0.8938691,0.64033019,1.249842791,0.671597698,DB0039010007515_,0.398095781,-0.112195935,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,digoxin,DB00390
,23753,DB00404,10007515,471,19421,375,9487,7.46181118351361e-12,0.61354239,0.533379924,0.706195687,2.91215600532525e-10,DB0040410007515_,21.95695723,-0.488505921,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,alprazolam,DB00404
,23754,DB00641,10007515,65,14059,111,12364,1.89926128522135e-05,0.515003373,0.372861405,0.706416467,0.000190943,DB0064110007515_,8.563534892,-0.663581829,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,simvastatin,DB00641
,23755,DB00715,10007515,56,4787,42,2245,0.028670698,0.625341074,0.410298769,0.959529641,0.08176297,DB0071510007515_,2.503930826,-0.469458059,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,paroxetine,DB00715
,23756,DB00335,10010264,155,8311,63,5402,0.001603964,1.599109366,1.183195002,2.183275956,0.00811319,DB0033510010264_,4.814264136,0.469446828,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,23757,DB00390,10010264,140,4005,56,3245,5.35975610097308e-06,2.025377827,1.470097338,2.823063587,6.28653231209627e-05,DB0039010010264_,9.674515848,0.705756264,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,23758,DB00715,10010264,96,4747,30,2257,0.053582997,1.521383545,0.996982418,2.382856045,0.131715054,DB0071510010264_,2.027114368,0.419620148,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,23761,DB00404,10011703,16,19876,34,9828,5.32657415351332e-07,0.232703173,0.11987122,0.433513848,8.20685824297173e-06,DB0040410011703_,11.71054038,-1.457991571,male,10011703,Cyanosis,10047065,Vascular disorders,Vasc,alprazolam,DB00404
,23773,DB00404,10014387,64,19828,26,9836,0.433492657,1.221050957,0.762460765,2.008648255,0.602015876,DB0040410014387_,0.507471462,0.199711928,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,alprazolam,DB00404
,23776,DB00722,10014387,74,25329,44,25988,0.004132788,1.725545076,1.17198384,2.567210521,0.017545076,DB0072210014387_,4.042981931,0.545542987,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,lisinopril,DB00722
,23779,DB00404,10029216,109,19783,35,9827,0.026178369,1.546968034,1.047486998,2.335446256,0.076142353,DB0040410029216_,2.57515063,0.436296908,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,23780,DB00641,10029216,55,14069,13,12462,2.26438410416529e-06,3.747217912,2.019978697,7.481146527,2.95527984994958e-05,DB0064110029216_,10.42933211,1.321013674,female,10029216,Nervousness,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,23781,DB00715,10029216,32,4811,19,2268,0.452434992,0.794020883,0.435478194,1.486052777,0.62005025,DB0071510029216_,0.477954756,-0.230645516,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,paroxetine,DB00715
,23782,DB00722,10029216,107,25296,40,25992,1.06620918126294e-08,2.748636027,1.894102464,4.059552563,2.38528146838634e-07,DB0072210029216_,15.24877852,1.011104798,female,10029216,Nervousness,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,23806,DB00404,10045555,65,19827,102,9760,1.52463102849798e-13,0.31370718,0.225967306,0.432819663,7.61880733537443e-12,DB0040410045555_,25.60040128,-1.159295276,male,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,23808,DB00722,10045555,70,25333,67,25965,0.732412725,1.07080464,0.754618439,1.52066369,0.844528198,DB0072210045555_,0.168977154,0.068410366,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,23816,DB00404,10049119,71,19821,13,9849,0.000420592,2.713745636,1.488934033,5.346750639,0.002670355,DB0040410049119_,5.925543781,0.998329834,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,23832,DB00390,10061024,32,4113,52,3249,0.001274574,0.486155448,0.302100391,0.77161975,0.006714538,DB0039010061024_,5.003480315,-0.721226854,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,digoxin,DB00390
,23833,DB00404,10061024,76,19816,36,9826,0.919936301,1.046817655,0.694758116,1.603854745,0.964555064,DB0040410061024_,0.036088358,0.045754757,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,alprazolam,DB00404
,23834,DB00641,10061024,60,14064,91,12384,0.001032986,0.580597891,0.411548516,0.813914787,0.005659031,DB0064110061024_,5.174502685,-0.54369686,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,simvastatin,DB00641
,23836,DB00722,10061024,124,25279,162,25870,0.043680089,0.783332702,0.614509241,0.996544398,0.112949448,DB0072210061024_,2.180814927,-0.244197766,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,lisinopril,DB00722
,23847,DB00005,10051062,41,128041,13,42406,1,1.044553475,0.548629712,2.124773964,1,DB0000510051062_,0,0.043589497,NA,10051062,Wrist surgery,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,23848,DB06643,10035664,294,52127,74,7441,3.60581185367795e-05,0.567139718,0.437605103,0.742983562,0.000333552,DB0664310035664_,8.005712165,-0.567149589,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,denosumab,DB06643
,23853,DB00335,10015090,53,8413,36,5429,0.828091707,0.950059298,0.609670328,1.495729064,0.90962391,DB0033510015090_,0.094724051,-0.051230878,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atenolol,DB00335
,23854,DB00451,10015090,244,47027,106,15313,0.0151201,0.749547569,0.593885848,0.951346745,0.049635548,DB0045110015090_,3.003048016,-0.288285495,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,23855,DB00635,10015090,180,32873,95,23699,0.014178339,1.365956605,1.058883373,1.771441096,0.047072793,DB0063510015090_,3.056060095,0.311854993,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,23856,DB00814,10015090,38,8249,12,3403,0.532954506,1.306301234,0.66726817,2.749446342,0.689723823,DB0081410015090_,0.371464018,0.267199658,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,meloxicam,DB00814
,23858,DB01015,10015090,63,9824,44,9337,0.121512696,1.360813768,0.910318413,2.050169015,0.243609277,DB0101510015090_,1.412189662,0.30808288,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,23859,DB11065,10028813,157,3029,79,2609,0.000103815,1.711620265,1.290984819,2.284308888,0.000824153,DB1106510028813_,7.101154456,0.537440445,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pancrelipase amylase,DB11065
,23860,DB11065,10047700,110,3076,52,2636,0.000406489,1.812612251,1.28616172,2.582849409,0.002597439,DB1106510047700_,5.953229281,0.594769038,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pancrelipase amylase,DB11065
,23861,DB09068,10013709,78,2317,46,940,0.055409019,0.688002356,0.467885993,1.0215051,0.135014499,DB0906810013709_,2.002373103,-0.373963016,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,vortioxetine,DB09068
,23862,DB08890,10019211,137,1810,11,548,1.16164376972186e-06,3.7695591,2.022258219,7.787687063,1.63544758902727e-05,DB0889010019211_,11.02100894,1.326958045,female,10019211,Headache,10029205,Nervous system disorders,Nerv,linaclotide,DB08890
,23864,DB00395,10013654,63,2121,54,682,5.91548456255722e-07,0.375287684,0.253962268,0.556143441,8.99297349489974e-06,DB0039510013654_,11.61906701,-0.980062389,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,carisoprodol,DB00395
,23865,DB00497,10013654,973,18294,1294,15081,5.18264690850264e-28,0.619887133,0.568230676,0.676044298,1.00908054807401e-25,DB0049710013654_,57.55558776,-0.47821786,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,23866,DB00153,10022086,161,7262,24,3415,3.58946360723838e-09,3.154375389,2.04154883,5.076882393,8.9008538600246e-08,DB0015310022086_,16.23453353,1.148790502,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,23867,DB00230,10022086,113,19561,21,8630,0.000100525,2.373930256,1.479698203,3.986512081,0.000801429,DB0023010022086_,7.129114465,0.864546918,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,23868,DB00863,10022086,117,10556,20,5820,7.11846287476292e-08,3.22518172,1.993529047,5.479481652,1.33031494250369e-06,DB0086310022086_,13.53009484,1.170989296,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,23869,DB01067,10022086,31,4330,23,4800,0.171471305,1.494048552,0.841919449,2.687680198,0.312810026,DB0106710022086_,1.162159219,0.401489584,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,23871,DB00158,10053425,226,16589,26,8078,1.62941763407556e-16,4.232028757,2.811158607,6.627224784,1.19135584177124e-14,DB0015810053425_,32.06109928,1.44268149,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,23872,DB00186,10053425,48,16853,9,9999,0.000521874,3.164182236,1.534812772,7.338593397,0.003199033,DB0018610053425_,5.744906801,1.151894645,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,23874,DB00316,10053425,212,65262,32,36921,1.27599280838083e-15,3.747950963,2.575520379,5.620579334,8.45888296804289e-14,DB0031610053425_,30.10097417,1.321209281,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,23875,DB00482,10053425,44,8215,9,3062,0.120343175,1.822218682,0.876555505,4.250501125,0.241819466,DB0048210053425_,1.419563838,0.600054815,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,23876,DB00863,10053425,53,10620,11,5829,0.002291586,2.644418238,1.363805689,5.619985578,0.010870663,DB0086310053425_,4.521687591,0.972451093,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,23879,DB01104,10053425,54,15409,10,7276,0.004439995,2.549746238,1.284535912,5.618976458,0.018574128,DB0110410053425_,3.985985628,0.93599384,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,23888,DB00480,10064658,71,67357,83,67579,0.375294791,0.858242797,0.616091072,1.192851028,0.545187552,DB0048010064658_,0.606625411,-0.15286824,NA,10064658,Osteonecrosis of jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,23889,DB01234,10064658,43,31582,45,32843,1,0.993708614,0.638556061,1.544459442,1,DB0123410064658_,0,-0.00631126,NA,10064658,Osteonecrosis of jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,23891,DB00005,10018964,44,128038,22,42397,0.117788968,0.662258581,0.38844358,1.160380523,0.23787661,DB0000510018964_,1.436003183,-0.412099194,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,23892,DB00005,10035759,37,128045,21,42398,0.066573519,0.583401011,0.3326209,1.049132473,0.155179795,DB0000510035759_,1.863170866,-0.538880489,NA,10035759,Pneumothorax,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,23896,DB00175,10000081,120,8011,69,6037,0.076144748,1.310563763,0.964738291,1.792239526,0.171720663,DB0017510000081_,1.761886173,0.270457398,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,23897,DB00381,10000081,426,28934,249,22638,0.000276673,1.338557217,1.140984165,1.573010285,0.001889901,DB0038110000081_,6.271230634,0.29159233,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,23898,DB00722,10000081,361,25042,294,25738,0.003580513,1.262009265,1.077780173,1.478637246,0.015601126,DB0072210000081_,4.160412157,0.232705105,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,23899,DB00169,10005483,159,38532,133,18042,1.46705269981165e-06,0.559803478,0.441484451,0.710643766,2.01786918966767e-05,DB0016910005483_,10.81088337,-0.580169489,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,23900,DB00169,10020947,94,38597,45,18130,0.92753868,0.981204632,0.680447174,1.433415566,0.969532707,DB0016910020947_,0.030941069,-0.018974246,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,23902,DB00331,10020947,36,24910,20,20732,0.178923538,1.498080883,0.843993132,2.732112911,0.322554453,DB0033110020947_,1.131483311,0.404184877,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,23903,DB00338,10020947,63,33611,27,22245,0.066469653,1.544273304,0.969068496,2.522525913,0.154999541,DB0033810020947_,1.864333124,0.434553447,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,23904,DB00381,10020947,36,29324,29,22858,0.901100969,0.967639744,0.576697444,1.636638279,0.956890778,DB0038110020947_,0.044066024,-0.032895426,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,23907,DB00331,10021027,76,24870,23,20729,6.34770655007315e-06,2.75400851,1.707441938,4.603639601,7.29716618106445e-05,DB0033110021027_,9.525439387,1.01305749,female,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,23908,DB00338,10021027,66,33608,57,22215,0.141070056,0.765387083,0.528583057,1.111229689,0.271391818,DB0033810021027_,1.304191679,-0.267373582,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,23909,DB00722,10021027,33,25370,32,26000,0.901372557,1.056880743,0.629700283,1.775810672,0.956927891,DB0072210021027_,0.044027239,0.055321875,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,23918,DB00331,10023676,535,24411,647,20105,8.12956518500509e-11,0.681046548,0.605281831,0.766055819,2.68618002373173e-09,DB0033110023676_,19.73514572,-0.384124622,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,23919,DB00338,10023676,36,33638,16,22256,0.203740789,1.488662441,0.805085591,2.873961325,0.35352191,DB0033810023676_,1.039809816,0.397878026,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,23920,DB00722,10023676,108,25295,197,25835,9.13290631851392e-07,0.559936246,0.438362947,0.712073592,1.32373003905232e-05,DB0072210023676_,11.23247193,-0.579932347,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,23921,DB00169,10027417,26,38665,30,18145,0.000852423,0.406720208,0.230960412,0.711745206,0.004825229,DB0016910027417_,5.333897062,-0.899629779,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,23923,DB00331,10027417,164,24782,260,20492,5.01639911161431e-11,0.521591425,0.42595737,0.637190313,1.71575862913184e-09,DB0033110027417_,20.1834105,-0.650870708,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,23924,DB00338,10027417,55,33619,46,22226,0.263172835,0.790475006,0.524385553,1.196414478,0.424972997,DB0033810027417_,0.855729648,-0.235121241,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,23925,DB00381,10027417,129,29231,77,22810,0.067278595,1.307308221,0.977751762,1.757928158,0.156480838,DB0038110027417_,1.854821718,0.26797023,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,23926,DB00722,10027417,49,25354,85,25947,0.003165707,0.589962775,0.406180155,0.848647703,0.014140644,DB0072210027417_,4.258702085,-0.527695837,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,23927,DB00169,10035669,56,38635,55,18120,0.000137778,0.477527058,0.323077709,0.706116427,0.001048643,DB0016910035669_,6.860258257,-0.739134455,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,23929,DB00331,10035669,17,24929,39,20713,0.000379286,0.362185306,0.192034817,0.655662879,0.002455195,DB0033110035669_,6.009549159,-1.015599302,male,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,metformin,DB00331
,23930,DB00338,10035669,59,33615,64,22208,0.007245794,0.609067895,0.420058245,0.881787495,0.027510574,DB0033810035669_,3.593184829,-0.495825532,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,omeprazole,DB00338
,23931,DB00381,10035669,56,29304,47,22840,0.765733611,0.928668122,0.618648128,1.399492534,0.870859639,DB0038110035669_,0.138274465,-0.074003846,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,amlodipine,DB00381
,23932,DB00722,10035669,27,25376,59,25973,0.001079431,0.468402071,0.285458561,0.750733324,0.005868218,DB0072210035669_,5.138204328,-0.758428226,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,lisinopril,DB00722
,23939,DB00480,10050256,37,67391,37,67625,1,1.003472342,0.618672266,1.627610614,1,DB0048010050256_,0,0.003466328,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,23941,DB08910,10010305,124,16620,100,17388,0.060231553,1.297285319,0.987900421,1.707098586,0.143892731,DB0891010010305_,1.938687181,0.260273865,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,pomalidomide,DB08910
,23942,DB08910,10023547,283,16461,326,17162,0.235615489,0.905079686,0.767925388,1.066146894,0.392779649,DB0891010023547_,0.934506513,-0.099732288,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,pomalidomide,DB08910
,23943,DB00028,10009033,51,13407,15,5600,0.279178259,1.420186773,0.785217237,2.721807208,0.443021042,DB0002810009033_,0.814138012,0.350788393,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human immunoglobulin g,DB00028
,23944,DB01075,10009033,94,19854,43,11054,0.325792227,1.217066438,0.8391212,1.790522516,0.494282752,DB0107510009033_,0.704647554,0.196443404,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,23945,DB01136,10009033,103,9781,69,11046,0.000920376,1.685755512,1.229159993,2.323960508,0.005147798,DB0113610009033_,5.269186172,0.522213838,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,23946,DB09140,10009033,168,3573,82,1716,0.890327652,0.983959478,0.746229368,1.305855248,0.954609926,DB0914010009033_,0.046452476,-0.016170564,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,23953,DB00028,10035664,386,13072,199,5416,0.01460266,0.803696344,0.67349943,0.961301326,0.048262405,DB0002810035664_,3.031102376,-0.218533763,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,23954,DB00281,10035664,392,11066,224,5447,0.081284068,0.861415907,0.72670541,1.023033459,0.180523429,DB0028110035664_,1.711894708,-0.14917784,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,lidocaine,DB00281
,23955,DB01075,10035664,547,19401,364,10733,0.007645042,0.831363087,0.725218371,0.953873602,0.028727653,DB0107510035664_,3.549895098,-0.184688651,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,23956,DB09140,10035664,453,3288,181,1617,0.027150137,1.230747498,1.022774615,1.485662296,0.078331743,DB0914010035664_,2.546802357,0.207621707,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,oxygen,DB09140
,23964,DB00814,10012378,183,8104,66,3349,0.360689114,1.145818585,0.857611424,1.546894054,0.530597344,DB0081410012378_,0.633751842,0.136119303,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,meloxicam,DB00814
,23966,DB00814,10012735,465,7822,140,3275,0.000670838,1.390646909,1.143452126,1.699632247,0.003954913,DB0081410012735_,5.532796687,0.329769041,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,23967,DB01394,10012735,133,1307,137,1866,0.012080407,1.385853986,1.071778721,1.791581425,0.041353584,DB0139410012735_,3.185596195,0.326316546,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,colchicine,DB01394
,23968,DB00814,10047895,153,8134,79,3336,0.108362038,0.794292341,0.599628972,1.059054329,0.223571127,DB0081410047895_,1.498025674,-0.230303698,NA,10047895,Weight decreased,10022891,Investigations,Inv,meloxicam,DB00814
,23969,DB01394,10047895,35,1405,36,1967,0.224162765,1.360967538,0.825319336,2.242280116,0.378721357,DB0139410047895_,0.97095455,0.308195872,NA,10047895,Weight decreased,10022891,Investigations,Inv,colchicine,DB01394
,23972,DB00563,10067482,152,46494,42,15306,0.359356598,1.191396787,0.84119194,1.720121791,0.529105575,DB0056310067482_,0.636567292,0.17512639,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,23976,DB00582,10034551,43,1087,27,1547,0.000860487,2.26587279,1.359106587,3.838217774,0.004867207,DB0058210034551_,5.325235076,0.817960022,NA,10034551,Periostitis,10028395,Musculoskeletal and connective tissue disorders,Musc,voriconazole,DB00582
,23978,DB01307,10003549,69,2455,50,2019,0.515043297,1.1348714,0.773243035,1.675778024,0.674904684,DB0130710003549_,0.393183806,0.126519341,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,insulin detemir,DB01307
,23979,DB01409,10003549,188,5843,115,3851,0.551462345,1.077456803,0.846616164,1.375996011,0.705499257,DB0140910003549_,0.348849561,0.074603452,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,23980,DB08890,10003549,48,1899,19,540,0.234602455,0.718486878,0.410414359,1.305929324,0.391449575,DB0889010003549_,0.937898573,-0.330607836,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,linaclotide,DB08890
,23981,DB00678,10013968,731,14868,438,10286,0.020641366,1.154580947,1.021450261,1.306271239,0.063361436,DB0067810013968_,2.758899868,0.143737462,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,23982,DB01307,10013968,120,2404,66,2003,0.008320173,1.514761943,1.105612668,2.090476969,0.030717853,DB0130710013968_,3.482911251,0.415258293,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin detemir,DB01307
,23983,DB08890,10013968,66,1881,23,536,0.436434715,0.817758767,0.496423539,1.391442276,0.6050308,DB0889010013968_,0.502475913,-0.201187892,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,linaclotide,DB08890
,23984,DB01307,10016256,117,2407,105,1964,0.490293249,0.909224829,0.687720667,1.203239262,0.6535803,DB0130710016256_,0.425289876,-0.095162878,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,insulin detemir,DB01307
,23985,DB01409,10016256,387,5644,170,3796,4.24196228691354e-06,1.531027705,1.268835394,1.853402721,5.11216891652917e-05,DB0140910016256_,9.881301705,0.425939213,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,23986,DB08890,10016256,129,1818,25,534,0.071543251,1.515365577,0.969509462,2.455030801,0.163950685,DB0889010016256_,1.808189597,0.415656715,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,linaclotide,DB08890
,23987,DB00682,10016322,386,19073,171,16193,4.07669891020944e-13,1.916392264,1.594510233,2.311029054,1.92380665807639e-11,DB0068210016322_,24.67413017,0.650444389,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,23988,DB00695,10016322,477,27572,199,20329,5.21504787231563e-12,1.767283076,1.493199815,2.09782303,2.10241615527325e-10,DB0069510016322_,22.2827637,0.569443382,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,23989,DB00996,10016322,699,38254,295,22130,5.19208218691575e-06,1.370747708,1.193354634,1.57754922,6.1185330770267e-05,DB0099610016322_,9.70160309,0.315356363,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,23990,DB01307,10016322,36,2488,18,2051,0.098285508,1.648537414,0.908806673,3.093585067,0.208299503,DB0130710016322_,1.568778315,0.499888479,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,insulin detemir,DB01307
,23991,DB01409,10016322,108,5923,36,3930,0.000283931,1.990412909,1.350334527,2.995452361,0.001928954,DB0140910016322_,6.250777208,0.688342109,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,23994,DB01409,10017955,61,5970,79,3887,5.71267396741328e-05,0.50276567,0.35305051,0.71306607,0.000494672,DB0140910017955_,7.611615977,-0.687631082,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,tiotropium,DB01409
,23996,DB00678,10041349,159,15440,99,10625,0.445703717,1.105227004,0.853485083,1.436979675,0.613576463,DB0067810041349_,0.488450389,0.100050747,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,losartan,DB00678
,23997,DB00695,10041349,314,27735,170,20358,0.001400312,1.355765629,1.120357263,1.645190373,0.007259803,DB0069510041349_,4.925402588,0.304366334,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,23999,DB01409,10041349,54,5977,39,3927,0.670977601,0.909727917,0.590272808,1.413502668,0.800371966,DB0140910041349_,0.222678702,-0.094609717,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,tiotropium,DB01409
,24004,DB00996,10049564,45,38908,15,22410,0.080238634,1.727906896,0.945098281,3.338279802,0.178803145,DB0099610049564_,1.721469826,0.546910789,NA,10049564,Impaired driving ability,10041244,Social circumstances,SocCi,gabapentin,DB00996
,24008,DB00678,10051792,36,15563,20,10704,0.49747026,1.237995879,0.697295754,2.258396947,0.659595353,DB0067810051792_,0.416128734,0.213493846,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,24010,DB00695,10051792,48,28001,37,20491,0.826678511,0.949381593,0.60521163,1.49987778,0.908584167,DB0069510051792_,0.095867751,-0.051944461,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,24011,DB00996,10051792,75,38878,36,22389,0.43005627,1.199708528,0.795781377,1.838920165,0.598524293,DB0099610051792_,0.513288165,0.182078634,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,24015,DB08890,10000060,42,1905,11,548,0.868845879,1.098313006,0.551092401,2.381906552,0.94160196,DB0889010000060_,0.060172642,0.093775371,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,linaclotide,DB08890
,24016,DB00619,10000081,43,2856,35,2459,0.82022545,1.057797898,0.658943323,1.708514903,0.904288487,DB0061910000081_,0.100606847,0.056189292,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,imatinib,DB00619
,24017,DB01254,10000081,41,3426,24,3124,0.104069802,1.557636822,0.916699265,2.701632723,0.217152872,DB0125410000081_,1.527153692,0.443169815,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,dasatinib,DB01254
,24018,DB00619,10012735,261,2638,175,2319,0.007902689,1.311009337,1.069389358,1.61012431,0.029491329,DB0061910012735_,3.523658999,0.270797327,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,imatinib,DB00619
,24019,DB01254,10012735,237,3230,204,2944,0.587334909,1.058908387,0.868400824,1.291948637,0.73446144,DB0125410012735_,0.308617783,0.057238554,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dasatinib,DB01254
,24026,DB00619,10047700,175,2724,92,2402,6.94484762672463e-05,1.677157511,1.287534569,2.196277935,0.000583119,DB0061910047700_,7.447119731,0.517100403,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,imatinib,DB00619
,24027,DB01254,10047700,106,3361,77,3071,0.13389139,1.257797671,0.925037192,1.716729194,0.261164213,DB0125410047700_,1.342605902,0.229362312,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dasatinib,DB01254
,24032,DB00635,10012218,69,32984,48,23746,0.925332711,1.034894876,0.705407385,1.529127524,0.968016012,DB0063510012218_,0.03250665,0.034299852,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,24034,DB00864,10012218,19,6850,32,8360,0.323882293,0.724651154,0.387709479,1.319276705,0.492317016,DB0086410012218_,0.708632429,-0.322064906,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,tacrolimus,DB00864
,24036,DB00635,10042458,84,32969,54,23740,0.546094271,1.120141196,0.786084138,1.607908715,0.700742839,DB0063510042458_,0.355614307,0.113454746,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,24043,DB00331,10006451,247,24699,78,20674,1.2182755530383e-15,2.650477857,2.045482388,3.466802311,8.08645780596256e-14,DB0033110006451_,30.14600052,0.974739947,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,metformin,DB00331
,24044,DB00736,10006451,151,10440,43,5510,0.000243872,1.853294869,1.310627213,2.669393914,0.001698287,DB0073610006451_,6.378135233,0.616965065,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,24045,DB00999,10006451,231,21199,76,12163,1.61912558038223e-05,1.743880848,1.338782218,2.293034354,0.000165606,DB0099910006451_,8.70589626,0.556113002,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,24047,DB01067,10006451,40,4321,28,4795,0.067450416,1.585187381,0.952044268,2.673126936,0.156793493,DB0106710006451_,1.852825669,0.460702622,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,glipizide,DB01067
,24050,DB00264,10035664,1136,28471,1103,23789,0.000526039,0.860554418,0.790008247,0.937422856,0.003218563,DB0026410035664_,5.738820321,-0.150178426,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,metoprolol,DB00264
,24051,DB00761,10035664,945,14362,532,8093,1,1.000955517,0.895913889,1.119155017,1,DB0076110035664_,0,0.000955061,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,24052,DB01020,10035664,67,1746,76,1802,0.609279036,0.909889121,0.640716829,1.289609067,0.751784976,DB0102010035664_,0.285304931,-0.094432532,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,isosorbide mononitrate,DB01020
,24053,DB01067,10035664,127,4234,177,4646,0.046934076,0.787355396,0.619429737,0.998543908,0.119332772,DB0106710035664_,2.125839285,-0.23907555,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,glipizide,DB01067
,24054,DB01591,10035664,56,1899,24,632,0.297568812,0.776628707,0.468992294,1.321772111,0.463474534,DB0159110035664_,0.769003839,-0.252792898,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,solifenacin,DB01591
,24056,DB00480,10013709,803,66625,782,66880,0.561171117,1.030791224,0.932382342,1.139608616,0.713647627,DB0048010013709_,0.337365958,0.030326686,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,24059,DB00060,10011224,52,9456,17,2448,0.374241077,0.791894841,0.449619998,1.463460879,0.544062759,DB0006010011224_,0.608690674,-0.233326673,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,interferon beta-1a,DB00060
,24060,DB00181,10011224,94,9762,53,5818,0.797438316,1.057030528,0.745765807,1.511921596,0.890446532,DB0018110011224_,0.116032221,0.055463588,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,baclofen,DB00181
,24061,DB00215,10011224,177,10926,52,5224,0.001682574,1.627421693,1.186144057,2.26610932,0.00844097,DB0021510011224_,4.774658078,0.486996979,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,24063,DB00999,10011224,458,20972,177,12062,5.38713584684572e-06,1.488218564,1.246655229,1.782922307,6.31301229310477e-05,DB0099910011224_,9.670312518,0.39757981,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,24064,DB00619,10019211,89,2810,38,2456,0.000198007,2.046735005,1.379241205,3.089011046,0.001428747,DB0061910019211_,6.550957591,0.716245843,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,imatinib,DB00619
,24065,DB00264,10067482,113,29494,46,24846,2.01944720861015e-05,2.069327337,1.455868684,2.98368727,0.000201408,DB0026410067482_,8.510176133,0.727223596,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,24066,DB00381,10067482,100,29260,55,22832,0.042357712,1.418742229,1.010512265,2.010007774,0.110398856,DB0038110067482_,2.20365551,0.349770725,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,24067,DB00404,10067482,60,19832,25,9837,0.491305405,1.190414495,0.734655026,1.982729528,0.654468,DB0040410067482_,0.423932587,0.174301561,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,24068,DB00472,10067482,47,10712,12,4300,0.193711684,1.572226331,0.820167198,3.259030959,0.341336167,DB0047210067482_,1.074887459,0.45249266,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,24069,DB00476,10067482,50,17207,26,6151,0.119416444,0.687455943,0.419433796,1.15159365,0.240452064,DB0047610067482_,1.425234529,-0.374757534,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,24070,DB00005,10008629,74,128008,23,42396,0.906500288,1.065585328,0.659594241,1.783577573,0.958224861,DB0000510008629_,0.042672809,0.063524252,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,etanercept,DB00005
,24075,DB00586,10025482,265,6844,43,2762,2.27788963312159e-09,2.486901874,1.790436041,3.528755828,5.87291113355577e-08,DB0058610025482_,16.6503303,0.911037709,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,24076,DB01098,10025482,262,7887,110,7099,5.26131072146862e-12,2.143660602,1.705194683,2.709870438,2.11944141477092e-10,DB0109810025482_,22.27469836,0.762514929,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,24077,DB00586,10061822,68,7041,12,2793,0.008329247,2.247683942,1.204501749,4.569734559,0.030741024,DB0058610061822_,3.482157234,0.809900327,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,24078,DB00678,10061822,80,15519,58,10666,0.794582802,0.948000548,0.667015249,1.354400514,0.888768227,DB0067810061822_,0.11791879,-0.053400198,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,24079,DB01098,10061822,65,8084,68,7141,0.338415241,0.844389493,0.590709107,1.206121856,0.507487124,DB0109810061822_,0.678283941,-0.169141407,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,24081,DB01075,10016825,287,19661,140,10957,0.204080071,1.142473795,0.928874843,1.410424766,0.353923708,DB0107510016825_,1.038673904,0.133195907,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,diphenhydramine,DB01075
,24083,DB01075,10042682,119,19829,49,11048,0.07615067,1.353099292,0.961570669,1.929490093,0.171724464,DB0107510042682_,1.76186404,0.302397733,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,24084,DB00512,10046735,77,4660,71,5027,0.362459991,1.169897479,0.834124136,1.642794654,0.532145159,DB0051210046735_,0.630838972,0.15691612,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,vancomycin,DB00512
,24085,DB01076,10046735,240,25507,144,25439,1.31114933417278e-06,1.662196975,1.345317388,2.059707821,1.82298652466181e-05,DB0107610046735_,10.91244936,0.508140206,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,24088,DB05812,10011906,7,175,1055,6898,4.68922150977161e-05,0.261561933,0.103315973,0.552552044,0.000418314,DB0581210011906_,7.779278477,-1.341084187,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,abiraterone,DB05812
,24090,DB00422,10012378,159,3276,87,2862,0.000527511,1.596507702,1.215440435,2.108485462,0.003225315,DB0042210012378_,5.736724527,0.467818558,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,methylphenidate,DB00422
,24091,DB00584,10012378,31,2050,21,1853,0.330556399,1.334233156,0.739570232,2.452247948,0.499271563,DB0058410012378_,0.694605117,0.288356712,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,enalapril,DB00584
,24092,DB01097,10012378,71,6194,13,1490,0.407884184,1.313755741,0.718852324,2.594592301,0.577319754,DB0109710012378_,0.549359,0.272890013,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,leflunomide,DB01097
,24093,DB00335,10012735,599,7867,280,5185,3.36338852216625e-06,1.409930357,1.215929632,1.637861815,4.1789963273524e-05,DB0033510012735_,10.08285436,0.343540311,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,24095,DB00422,10012735,109,3326,69,2880,0.047335714,1.367809823,0.998143962,1.885062351,0.120080995,DB0042210012735_,2.119588802,0.313210791,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,methylphenidate,DB00422
,24096,DB00472,10012735,481,10278,148,4164,0.003889026,1.316629535,1.088852838,1.59964262,0.016671786,DB0047210012735_,4.09403746,0.275075089,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,24097,DB00584,10012735,136,1945,111,1763,0.430712352,1.110536649,0.850508862,1.452569849,0.599199438,DB0058410012735_,0.512160785,0.104843366,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,enalapril,DB00584
,24098,DB01097,10012735,288,5977,87,1416,0.060348425,0.78427407,0.610404365,1.015800615,0.144093365,DB0109710012735_,1.937293821,-0.242996741,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,leflunomide,DB01097
,24100,DB00422,10028813,226,3209,76,2873,1.63214289581152e-14,2.661742414,2.033491455,3.51659082,9.3465960820056e-13,DB0042210028813_,27.69859399,0.978980951,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,methylphenidate,DB00422
,24101,DB01097,10028813,341,5924,81,1422,1,1.010540757,0.785099345,1.313168742,1,DB0109710028813_,0,0.01048559,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,leflunomide,DB01097
,24102,DB01156,10028813,1022,12600,228,6100,2.31052176636958e-28,2.170002535,1.871684035,2.524305698,4.56632064879882e-26,DB0115610028813_,58.34850465,0.774728336,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,24104,DB00451,10008111,70,47201,44,15375,0.000982039,0.518250489,0.35027797,0.774065277,0.005422878,DB0045110008111_,5.217128635,-0.657296584,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,24107,DB09053,10008111,21,2264,32,4020,0.569574092,1.165212439,0.636920347,2.089711019,0.720412626,DB0905310008111_,0.327931139,0.152903421,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,ibrutinib,DB09053
,24108,DB00451,10055798,214,47057,74,15345,0.680732576,0.943023993,0.720312146,1.246431832,0.806956762,DB0045110055798_,0.214485191,-0.058663554,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,24111,DB09053,10055798,22,2263,65,3987,0.042340917,0.59635353,0.349085604,0.983317838,0.110371499,DB0905310055798_,2.203903341,-0.516921617,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,ibrutinib,DB09053
,24112,DB00316,10002424,65,65409,57,36896,0.017993568,0.643223717,0.443653594,0.934920248,0.056846265,DB0031610002424_,2.867404761,-0.441262688,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,24115,DB00863,10002424,37,10636,24,5816,0.505552683,0.843035033,0.490491199,1.474565643,0.666419265,DB0086310002424_,0.405836279,-0.170746764,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,24116,DB00904,10002424,39,23030,16,14440,0.166902706,1.528315411,0.834237456,2.930614468,0.306705683,DB0090410002424_,1.18186668,0.424166091,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,24118,DB01075,10002424,54,19894,39,11058,0.233283903,0.769658389,0.500098528,1.19418398,0.389869493,DB0107510002424_,0.941943228,-0.261808514,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,24121,DB08890,10000081,65,1882,15,544,0.496732544,1.252455257,0.69961284,2.384332137,0.658892558,DB0889010000081_,0.417194796,0.22510583,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,linaclotide,DB08890
,24123,DB00252,10007515,25,2207,45,1863,0.002350082,0.469043396,0.274480963,0.784855808,0.011090107,DB0025210007515_,4.501701863,-0.757059986,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,phenytoin,DB00252
,24126,DB00252,10033295,42,2190,47,1861,0.236887177,0.759425991,0.486327166,1.182445469,0.394224537,DB0025210033295_,0.930834641,-0.275192406,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,phenytoin,DB00252
,24127,DB00252,10057856,28,2204,34,1874,0.198955424,0.700291182,0.40738432,1.194787466,0.347813064,DB0025210057856_,1.056090115,-0.356259057,NA,10057856,Anticonvulsant drug level increased,10022891,Investigations,Inv,phenytoin,DB00252
,24129,DB00958,10003988,116,4478,33,2552,0.000272422,2.003100188,1.345895895,3.054940107,0.001864502,DB0095810003988_,6.284761142,0.694696074,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,carboplatin,DB00958
,24130,DB01229,10003988,187,5554,45,2664,1.65537702656085e-05,1.993087682,1.427529463,2.834444951,0.00016901,DB0122910003988_,8.685553578,0.689685035,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,paclitaxel,DB01229
,24131,DB00958,10021143,40,4554,39,2546,0.017807265,0.573420657,0.358549184,0.917806783,0.056399428,DB0095810021143_,2.875296257,-0.5561357,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carboplatin,DB00958
,24132,DB01229,10021143,51,5690,43,2666,0.005338886,0.555783854,0.362072619,0.856600605,0.021553159,DB0122910021143_,3.837232876,-0.587375811,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,paclitaxel,DB01229
,24133,DB00958,10037377,75,4519,40,2545,0.844955331,1.055954607,0.707751255,1.596219926,0.921715259,DB0095810037377_,0.081518933,0.054445199,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carboplatin,DB00958
,24134,DB00958,10038695,57,4537,62,2523,0.000332478,0.511284496,0.34925452,0.74735884,0.00219605,DB0095810038695_,6.121095032,-0.6708291,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carboplatin,DB00958
,24135,DB01229,10038695,38,5703,46,2663,1.71105331036858e-05,0.385785834,0.243662087,0.607696556,0.000174086,DB0122910038695_,8.655962948,-0.952472898,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,paclitaxel,DB01229
,24136,DB00958,10048959,33,4561,18,2567,1,1.03182478,0.563056402,1.9505057,1,DB0095810048959_,0,0.031328866,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,24137,DB01229,10048959,40,5701,20,2689,0.889683641,0.943350726,0.537406755,1.706715342,0.954191877,DB0122910048959_,0.046890499,-0.05831714,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,24140,DB01229,10017955,36,5705,19,2690,0.666653348,0.893416264,0.497974992,1.652095262,0.797361892,DB0122910017955_,0.226446636,-0.112702665,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,paclitaxel,DB01229
,24141,DB01229,10018884,77,5664,29,2680,0.345971691,1.256263596,0.807721306,2.002932279,0.515379196,DB0122910018884_,0.662852347,0.228141916,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,paclitaxel,DB01229
,24142,DB01229,10021097,96,5645,88,2621,6.74441105082325e-06,0.506541362,0.373871155,0.687005119,7.69430748571567e-05,DB0122910021097_,9.472444697,-0.680149297,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,paclitaxel,DB01229
,24143,DB00575,10005750,100,5144,88,3741,0.204976546,0.826448175,0.612320012,1.117053532,0.35506844,DB0057510005750_,1.03544472,-0.190618068,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,clonidine,DB00575
,24144,DB00207,10006451,175,8905,63,5392,0.000330576,1.681894036,1.251534136,2.285116003,0.002185957,DB0020710006451_,6.125701514,0.519920561,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,azithromycin,DB00207
,24151,DB00207,10044565,54,9026,24,5431,0.241826833,1.353811707,0.821577008,2.292686773,0.399963399,DB0020710044565_,0.916382239,0.302924101,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,24153,DB00207,10047895,122,8958,112,5343,0.001330181,0.649750509,0.497396698,0.849337678,0.006965593,DB0020710047895_,4.966772498,-0.431166822,NA,10047895,Weight decreased,10022891,Investigations,Inv,azithromycin,DB00207
,24154,DB08890,10047895,47,1900,12,547,0.874225964,1.127534323,0.583829397,2.352178656,0.945463987,DB0889010047895_,0.056079481,0.120033233,NA,10047895,Weight decreased,10022891,Investigations,Inv,linaclotide,DB08890
,24159,DB01203,10016256,51,648,32,473,0.565246396,1.163185237,0.720652963,1.901579726,0.716865154,DB0120310016256_,0.332867525,0.151162136,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,nadolol,DB01203
,24160,DB00338,10027951,58,33616,30,22242,0.326667908,1.279177742,0.809368268,2.06002349,0.495078566,DB0033810027951_,0.70303881,0.246217482,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,24166,DB00338,10034972,38,33636,18,22254,0.275630462,1.396729119,0.777588808,2.600600853,0.438888185,DB0033810034972_,0.823510603,0.33413316,NA,10034972,Photosensitivity reaction,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,24173,DB08904,10001760,209,11401,14,3545,8.03950950772722e-12,4.641633848,2.700534589,8.64940241,3.11909236030421e-10,DB0890410001760_,21.88830888,1.535066427,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,certolizumab pegol,DB08904
,24176,DB08904,10035664,208,11402,66,3493,0.829118194,0.965465884,0.72658396,1.297072045,0.910222971,DB0890410035664_,0.094065686,-0.035144513,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,24177,DB06285,10022437,104,8746,11,1095,0.76461108,1.183732873,0.632363181,2.452205028,0.870053562,DB0628510022437_,0.139200504,0.168672897,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,teriparatide,DB06285
,24178,DB06285,10033425,330,8520,28,1078,0.048244502,1.491143923,1.006547951,2.290883276,0.121792809,DB0628510033425_,2.105433962,0.399543559,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,teriparatide,DB06285
,24183,DB01240,10061818,148,5603,50,1526,0.189448615,0.806193311,0.578187677,1.140166951,0.3358506,DB0124010061818_,1.091088861,-0.215431725,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,24185,DB00987,10029366,42,2062,56,2872,0.836808983,1.044638124,0.680145574,1.593614588,0.915736136,DB0098710029366_,0.088027017,0.043670533,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,cytarabine,DB00987
,24186,DB00869,10015946,68,1237,34,895,0.099522557,1.446816391,0.935756417,2.273856306,0.210102227,DB0086910015946_,1.560161072,0.36936555,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,dorzolamide,DB00869
,24191,DB00563,10014625,64,46582,61,15287,7.89460364763349e-09,0.344333276,0.238504272,0.497479683,1.81468873526932e-07,DB0056310014625_,15.52218169,-1.066145264,male,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,24193,DB00741,10014625,36,4058,32,3142,0.623706055,0.871075564,0.52462049,1.452248534,0.763689088,DB0074110014625_,0.269594526,-0.13802655,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,hydrocortisone,DB00741
,24194,DB00531,10017955,25,7227,38,6478,0.042894325,0.589739407,0.340792347,1.003976404,0.111497948,DB0053110017955_,2.193749091,-0.528074522,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,24195,DB00563,10017955,87,46559,44,15304,0.025219909,0.649937257,0.44705577,0.956948976,0.073984969,DB0056310017955_,2.603893331,-0.430879448,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,24212,DB00563,10043089,30,46616,36,15312,3.73470092280816e-07,0.273736725,0.162784822,0.457261967,5.94228896828162e-06,DB0056310043089_,12.03341615,-1.295588494,male,10043089,Tachypnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,24217,DB00531,10054889,30,7222,61,6455,0.000192584,0.439595436,0.273730645,0.692325839,0.001395857,DB0053110054889_,6.57424661,-0.82190044,NA,10054889,Transaminases increased,10022891,Investigations,Inv,cyclophosphamide,DB00531
,24218,DB00563,10054889,193,46453,107,15241,2.88256309330363e-05,0.591803942,0.464523514,0.757258047,0.000274026,DB0056310054889_,8.202287804,-0.524579879,NA,10054889,Transaminases increased,10022891,Investigations,Inv,methotrexate,DB00563
,24222,DB00987,10054889,19,2085,46,2882,0.042596595,0.570992958,0.314951864,0.99734113,0.110905999,DB0098710054889_,2.199072296,-0.560378403,NA,10054889,Transaminases increased,10022891,Investigations,Inv,cytarabine,DB00987
,24235,DB00531,10074170,38,7214,57,6459,0.013401417,0.596923121,0.384627121,0.917085333,0.04495358,DB0053110074170_,3.102124868,-0.51596695,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,24236,DB00563,10074170,66,46580,42,15306,0.001123402,0.516341534,0.345331097,0.779786543,0.00606275,DB0056310074170_,5.105591857,-0.660986846,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,24239,DB00773,10074170,30,2293,28,2799,0.353333711,1.307784892,0.752597793,2.278873303,0.523114599,DB0077310074170_,0.64795472,0.268334784,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,etoposide,DB00773
,24244,DB00213,10020937,193,18702,94,13327,0.002570653,1.463081207,1.136405418,1.894539609,0.011926505,DB0021310020937_,4.428992086,0.380544628,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,24245,DB00264,10020937,305,29302,160,24732,8.35325395697887e-07,1.60892918,1.323389977,1.962149253,1.22252383217812e-05,DB0026410020937_,11.31200803,0.475568852,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,24246,DB00588,10020937,184,16340,52,8416,7.62548563477798e-05,1.822462675,1.331332016,2.532522739,0.00063219,DB0058810020937_,7.366320325,0.600188705,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,24247,DB00213,10028810,243,18652,115,13306,0.000290765,1.507387002,1.201158287,1.900869826,0.001966509,DB0021310028810_,6.231495348,0.41037769,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,24251,DB00213,10043607,193,18702,129,13292,0.609365156,1.063343246,0.845490057,1.340864551,0.75180301,DB0021310043607_,0.285280944,0.06141795,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,pantoprazole,DB00213
,24252,DB00264,10043607,235,29372,222,24670,0.220260759,0.889102615,0.736334321,1.07384211,0.373774615,DB0026410043607_,0.984102298,-0.117542623,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,24253,DB00958,10029366,237,4357,47,2538,1.89191223329529e-13,2.936956789,2.13103017,4.123223473,9.37397041511155e-12,DB0095810029366_,25.39308437,1.077373939,female,10029366,Neutrophil count decreased,10022891,Investigations,Inv,carboplatin,DB00958
,24259,DB00783,10002034,115,16599,7,366,0.017618727,0.362280708,0.168641737,0.92774641,0.055961361,DB0078310002034_,2.883093804,-1.01533593,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,estradiol,DB00783
,24274,DB01373,10035664,711,22009,362,7019,5.38186692352451e-12,0.626388298,0.549547784,0.714919016,2.1597308715243e-10,DB0137310035664_,22.25586731,-0.467784815,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,calcium,DB01373
,24275,DB00741,10013709,198,3896,115,3059,0.012175083,1.351791162,1.063374254,1.724760873,0.041631594,DB0074110013709_,3.178895918,0.301430499,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,24276,DB00996,10005750,252,38701,141,22284,0.833546321,1.029088536,0.833522531,1.274660072,0.913570529,DB0099610005750_,0.090394699,0.028673494,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,gabapentin,DB00996
,24280,DB00203,10005557,66,13812,42,8896,1,1.012121764,0.676503626,1.529192671,1,DB0020310005557_,0,0.012048884,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,sildenafil,DB00203
,24281,DB00635,10005557,191,32862,177,23617,0.016951707,0.775527319,0.62834287,0.957606422,0.054262389,DB0063510005557_,2.913923947,-0.25421207,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,prednisone,DB00635
,24282,DB00682,10005557,87,19372,77,16287,0.753854344,0.949912847,0.690453633,1.309082302,0.861598714,DB0068210005557_,0.148965646,-0.051385038,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,warfarin,DB00682
,24284,DB08932,10005557,85,19358,31,6566,0.748317515,0.930027293,0.609223654,1.453611013,0.857074656,DB0893210005557_,0.154230251,-0.072541346,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,macitentan,DB08932
,24289,DB08932,10008796,37,19406,14,6583,0.747503203,0.896514814,0.473037127,1.796456077,0.856444509,DB0893210008796_,0.154965752,-0.109240462,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,macitentan,DB08932
,24290,DB00046,10020751,51,5408,17,4675,0.000357642,2.593052577,1.47053185,4.796625808,0.002334685,DB0004610020751_,6.059878406,0.952835783,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,insulin lispro,DB00046
,24291,DB00203,10020751,119,13759,47,8891,0.003967496,1.636076222,1.156670298,2.34738208,0.016968049,DB0020310020751_,4.076423147,0.492300828,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,sildenafil,DB00203
,24292,DB00635,10020751,379,32674,111,23683,3.59702519080674e-19,2.474795579,1.996475459,3.088457864,3.46328963884085e-17,DB0063510020751_,37.90172768,0.906157798,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,prednisone,DB00635
,24293,DB00682,10020751,160,19299,64,16300,1.72456904829456e-07,2.111419638,1.569418378,2.86992666,2.97150425659931e-06,DB0068210020751_,12.72644225,0.747360535,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,warfarin,DB00682
,24296,DB00046,10030124,64,5395,57,4635,0.854918015,0.96462623,0.66290426,1.406762363,0.929630334,DB0004610030124_,0.072968262,-0.036014579,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,24297,DB01088,10030124,82,1347,23,414,0.812543328,1.09571493,0.672736631,1.848242501,0.899195915,DB0108810030124_,0.106254343,0.091407055,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,iloprost,DB01088
,24299,DB00203,10037087,204,13674,84,8854,0.000412312,1.5724841,1.212036451,2.05547829,0.002627621,DB0020310037087_,5.941676245,0.452656599,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,sildenafil,DB00203
,24301,DB01307,10037087,57,2467,22,2047,0.001937773,2.149432217,1.288377479,3.705964769,0.009487633,DB0130710037087_,4.657766118,0.765203722,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,insulin detemir,DB01307
,24302,DB08932,10037087,392,19051,74,6523,8.91758952352318e-07,1.813820305,1.409180207,2.361764669,1.2957370957756e-05,DB0893210037087_,11.25384575,0.595435287,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,macitentan,DB08932
,24303,DB00046,10042674,40,5419,14,4678,0.002488879,2.466161804,1.311618795,4.914119123,0.011623021,DB0004610042674_,4.454767583,0.902663017,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,24304,DB00203,10042674,279,13599,98,8840,6.57744263907019e-08,1.850595307,1.462668132,2.357824579,1.23800988018589e-06,DB0020310042674_,13.6020054,0.615507375,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,24305,DB00635,10042674,363,32690,138,23656,3.08945796829957e-11,1.903473366,1.559345963,2.334525045,1.09295292996977e-09,DB0063510042674_,20.63438269,0.643680305,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,24306,DB00682,10042674,255,19204,110,16254,1.30430769570874e-09,1.962006471,1.561307202,2.479178779,3.5398789655864e-08,DB0068210042674_,17.15658821,0.673967659,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,24310,DB00203,10042682,99,13779,33,8905,0.000651385,1.938763341,1.294275155,2.971624353,0.003857964,DB0020310042682_,5.557615752,0.662050317,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,24311,DB00682,10042682,83,19376,35,16329,0.000410447,1.998433948,1.33033714,3.059369434,0.002618589,DB0068210042682_,5.945119677,0.692363848,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,24314,DB08932,10042682,133,19310,27,6570,0.013529164,1.675883159,1.100544926,2.640123988,0.045289618,DB0893210042682_,3.094677454,0.516340285,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,24315,DB00046,10046571,143,5316,41,4651,1.34301643911313e-11,3.051004862,2.137316119,4.440446268,5.01081435089973e-10,DB0004610046571_,21.41425248,1.115470999,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,insulin lispro,DB00046
,24317,DB01307,10046571,79,2445,19,2050,9.47692993875765e-08,3.485218504,2.083347121,6.11369222,1.72269089516075e-06,DB0130710046571_,13.27162302,1.248530741,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,insulin detemir,DB01307
,24318,DB08932,10046571,524,18919,76,6521,1.22273230478466e-14,2.376272398,1.861901855,3.069250932,7.10265605110824e-13,DB0893210046571_,27.9731374,0.865533041,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,24320,DB00316,10005725,65,65409,55,36898,0.028638982,0.666710463,0.45825667,0.972943681,0.081694128,DB0031610005725_,2.504773154,-0.405399416,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,acetaminophen,DB00316
,24322,DB00316,10005802,90,65384,37,36916,0.115845558,1.373354359,0.926676186,2.072604844,0.234944678,DB0031610005802_,1.448405204,0.317256185,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,24324,DB01268,10020772,136,2007,163,2967,0.089484749,1.233389366,0.967924769,1.569756141,0.194444395,DB0126810020772_,1.637609041,0.209765962,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,sunitinib,DB01268
,24325,DB01268,10030124,31,2112,26,3104,0.041295204,1.752089326,1.003516135,3.08225589,0.108316978,DB0126810030124_,2.222693369,0.560808977,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,24327,DB09068,10016322,79,2316,36,950,0.602763948,0.900173391,0.59488831,1.38510551,0.746568874,DB0906810016322_,0.292267404,-0.105167878,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,vortioxetine,DB09068
,24330,DB01255,10037211,18,2115,38,1540,0.000176272,0.345002422,0.184587665,0.622281369,0.001296435,DB0125510037211_,6.648137452,-1.064203841,male,10037211,Psychomotor hyperactivity,10029205,Nervous system disorders,Nerv,lisdexamfetamine,DB01255
,24331,DB00273,10061422,42,8439,20,2173,0.027104585,0.540786736,0.309762501,0.974406906,0.078240028,DB0027310061422_,2.547973899,-0.614730282,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,24332,DB00635,10061422,30,33023,24,23770,0.78284202,0.89975454,0.50838467,1.608608971,0.881806742,DB0063510061422_,0.12578236,-0.105633287,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,24334,DB00073,10044565,53,7353,62,6345,0.110781777,0.737672867,0.500583748,1.083713626,0.227261298,DB0007310044565_,1.481654832,-0.304254822,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,rituximab,DB00073
,24337,DB00363,10029368,149,4479,213,6675,0.703318755,1.04252996,0.836898807,1.295933758,0.82205276,DB0036310029368_,0.195950701,0.041650413,NA,10029368,Neutrophil count increased,10022891,Investigations,Inv,clozapine,DB00363
,24338,DB00363,10047943,126,4502,184,6704,0.860429284,1.019726151,0.80373367,1.290351112,0.934271764,DB0036310047943_,0.067987915,0.019534111,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,clozapine,DB00363
,24344,DB08868,10020937,382,8820,101,2410,0.820866926,1.033463259,0.823799747,1.306119409,0.904598656,DB0886810020937_,0.100263907,0.032915549,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,24346,DB13961,10020937,130,9327,67,6347,0.067939701,1.320345087,0.97407611,1.803717777,0.157588691,DB1396110020937_,1.847766859,0.277893132,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,24349,DB00480,10017533,76,67352,34,67628,5.31351817696364e-05,2.24444973,1.479130906,3.469621162,0.000465165,DB0048010017533_,7.673118133,0.808460382,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,24358,DB00480,10019974,359,67069,371,67291,0.710587668,0.970851998,0.837034036,1.125953595,0.827403068,DB0048010019974_,0.189463317,-0.029581245,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,24360,DB01068,10019974,46,13717,20,6820,0.695278044,1.143528415,0.662458577,2.042546013,0.816560818,DB0106810019974_,0.202653883,0.134118583,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,clonazepam,DB01068
,24361,DB01104,10019974,66,15397,27,7259,0.579048946,1.152431064,0.725525745,1.877914693,0.727773999,DB0110410019974_,0.31776472,0.141873679,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,sertraline,DB01104
,24365,DB00046,10033371,133,5326,80,4612,0.012240415,1.439571908,1.079580201,1.929814514,0.041816912,DB0004610033371_,3.174454436,0.364345783,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,24367,DB00338,10033371,1416,32258,546,21726,1.70031489732979e-29,1.746656494,1.578890144,1.93437164,3.64838996541335e-27,DB0033810033371_,60.87551155,0.557703386,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,24368,DB01307,10033371,79,2445,44,2025,0.042903404,1.486904374,1.010536004,2.212324989,0.111500491,DB0130710033371_,2.19372628,0.396696357,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,insulin detemir,DB01307
,24370,DB00230,10033645,33,19641,17,8634,0.644981733,0.853341509,0.461542443,1.634424139,0.780792376,DB0023010033645_,0.247446008,-0.158595449,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,24372,DB00338,10033645,121,33553,91,22181,0.361356583,0.879014433,0.663825734,1.167408054,0.531226358,DB0033810033645_,0.632567063,-0.128953962,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,24373,DB00425,10033645,43,12652,28,7456,0.712541767,0.905024314,0.548955435,1.514148276,0.829078987,DB0042510033645_,0.187439849,-0.099793469,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,24374,DB00437,10033645,23,6898,48,11498,0.393267735,0.798698661,0.463255783,1.340428881,0.563186891,DB0043710033645_,0.57414375,-0.22477155,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,24375,DB01076,10033645,121,25626,98,25485,0.136535263,1.227893274,0.93242181,1.620389568,0.264848485,DB0107610033645_,1.328597371,0.205299915,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,24376,DB01104,10033645,32,15431,19,7267,0.453147195,0.793186951,0.435767225,1.482116639,0.620735025,DB0110410033645_,0.476850979,-0.231696333,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,24377,DB01307,10033645,31,2493,25,2044,1,1.016668294,0.578903069,1.802139249,1,DB0130710033645_,0,0.016530902,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,insulin detemir,DB01307
,24378,DB00005,10023547,227,127855,78,42341,0.790912854,0.963770681,0.741868056,1.263429345,0.886704293,DB0000510023547_,0.120243731,-0.036901896,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,etanercept,DB00005
,24379,DB00005,10062237,87,127995,40,42379,0.099663008,0.720141753,0.48973035,1.075282776,0.210252591,DB0000510062237_,1.559445657,-0.328307207,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,etanercept,DB00005
,24383,DB00316,10003445,123,65351,75,36878,0.604571857,0.925464664,0.688678477,1.250711872,0.747842343,DB0031610003445_,0.290563095,-0.077459328,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,24386,DB00230,10011906,307,19367,278,8373,4.22193199073931e-18,0.477434865,0.403777253,0.564806,3.67461862174115e-16,DB0023010011906_,35.53991214,-0.739327537,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,24387,DB00230,10012174,183,19491,70,8581,0.337640599,1.150938566,0.868174099,1.540379308,0.506817609,DB0023010012174_,0.679604085,0.140577754,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,pregabalin,DB00230
,24388,DB00321,10012174,66,7381,23,2827,0.811952155,1.099062215,0.673129502,1.855295279,0.898995888,DB0032110012174_,0.106476818,0.094457284,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,amitriptyline,DB00321
,24390,DB00321,10012735,279,7168,83,2767,0.041900866,1.29752832,1.007832598,1.685310704,0.109506762,DB0032110012735_,2.211768979,0.260461162,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,amitriptyline,DB00321
,24393,DB00321,10047700,205,7242,32,2818,2.03066668006537e-07,2.49257213,1.706444729,3.750148268,3.44028834582779e-06,DB0032110047700_,12.57995527,0.913315161,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,amitriptyline,DB00321
,24399,DB00316,10058467,67,65407,42,36911,0.618229578,0.900240949,0.603015038,1.357681434,0.759105174,DB0031610058467_,0.275614941,-0.105092831,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,24402,DB00682,10043607,318,19141,269,16095,0.966685286,0.994033649,0.841194233,1.175301594,1,DB0068210043607_,0,-0.00598422,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,warfarin,DB00682
,24403,DB00682,10048959,610,18849,315,16049,4.05439185639883e-13,1.64881386,1.434356635,1.898147882,1.91499892085253e-11,DB0068210048959_,24.67871896,0.500056157,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,24404,DB00682,10018985,72,19387,225,16139,4.13947989497521e-26,0.266398053,0.201203146,0.349121653,6.86474631163554e-24,DB0068210018985_,53.33564315,-1.322763649,male,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,24405,DB00682,10042361,109,19350,265,16099,5.89621852609628e-23,0.34222442,0.27098007,0.429784479,7.98876824528045e-21,DB0068210042361_,46.27625037,-1.072288559,male,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,24406,DB00005,10015916,278,127804,69,42350,0.03433822,1.335053884,1.022093134,1.764477995,0.094087366,DB0000510015916_,2.363531499,0.288971653,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,etanercept,DB00005
,24411,DB08890,10025482,81,1866,12,547,0.030031969,1.978140432,1.062901126,4.016554327,0.084784952,DB0889010025482_,2.467637209,0.682157228,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,linaclotide,DB08890
,24417,DB06228,10042609,56,15856,46,16030,0.321867046,1.230740353,0.817852119,1.860359461,0.490166588,DB0622810042609_,0.71300997,0.207615901,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,rivaroxaban,DB06228
,24418,DB06228,10051373,25,15887,39,16037,0.103367046,0.647090158,0.375110256,1.097169178,0.216072434,DB0622810051373_,1.532141586,-0.435269646,NA,10051373,Wound haemorrhage,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,24419,DB06228,10061623,68,15844,61,16015,0.537199259,1.126780532,0.78510451,1.620165126,0.69338113,DB0622810061623_,0.366175459,0.11936448,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,24420,DB01029,10020772,48,1292,16,885,0.013454052,2.054341299,1.137538165,3.902060742,0.045081236,DB0102910020772_,3.099289176,0.719955261,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,irbesartan,DB01029
,24421,DB00065,10003549,49,9415,24,4933,0.90176612,1.069733537,0.642994891,1.825127396,0.957082614,DB0006510003549_,0.043865565,0.067409587,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,24422,DB00065,10008531,63,9401,60,4897,0.001101066,0.546948103,0.377247222,0.793785601,0.005959948,DB0006510008531_,5.122693548,-0.603401358,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,24423,DB00316,10008531,587,64887,433,36520,2.67321871393213e-05,0.763018883,0.672299929,0.866464155,0.000255977,DB0031610008531_,8.270424848,-0.270472499,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,24425,DB00836,10008531,55,5480,33,4042,0.386770521,1.229292225,0.782648425,1.957977112,0.556841931,DB0083610008531_,0.585473866,0.206438577,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,24426,DB00065,10013573,109,9355,43,4914,0.122355427,1.331514099,0.925743967,1.9453596,0.244803988,DB0006510013573_,1.407297437,0.286316715,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,infliximab,DB00065
,24427,DB00836,10013573,196,5339,120,3955,0.118001604,1.209909003,0.955377125,1.537354022,0.23818708,DB0083610013573_,1.434698862,0.190545153,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,24428,DB00316,10013946,392,65082,163,36790,0.000877641,1.359458877,1.12911207,1.642873632,0.004948793,DB0031610013946_,5.308611664,0.307086736,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,24429,DB00836,10013946,51,5484,33,4042,0.581403653,1.139035261,0.719527718,1.825689271,0.729756466,DB0083610013946_,0.315044409,0.130181642,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,24432,DB00065,10022437,36,9428,17,4940,0.773918998,1.109573032,0.606594562,2.108851142,0.876603502,DB0006510022437_,0.131700496,0.103975286,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,infliximab,DB00065
,24433,DB00836,10022437,77,5458,53,4022,0.721792118,1.070597758,0.742966906,1.552738592,0.836058645,DB0083610022437_,0.179056519,0.068217145,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,loperamide,DB00836
,24434,DB00065,10024690,35,9429,21,4936,0.672712742,0.872499946,0.493327489,1.579112403,0.801352991,DB0006510024690_,0.221453741,-0.136392687,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,infliximab,DB00065
,24438,DB00316,10026865,52,65422,33,36920,0.65149014,0.889261328,0.56395504,1.420405636,0.785884274,DB0031610026865_,0.240945732,-0.117364129,NA,10026865,Mass,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,24442,DB00316,10029410,172,65302,98,36855,0.949449943,0.990538406,0.768226575,1.283198934,0.987820288,DB0031610029410_,0.012254493,-0.009506639,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,24446,DB00836,10042128,46,5489,28,4047,0.479307604,1.211242451,0.739721455,2.016104033,0.644364554,DB0083610042128_,0.439490635,0.191646652,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,24448,DB00316,10047571,366,65108,101,36852,1.80851018428724e-11,2.05108254,1.640647531,2.583457359,6.61610162755604e-10,DB0031610047571_,21.13634461,0.718367722,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,acetaminophen,DB00316
,24450,DB00836,10047571,47,5488,13,4062,0.000937953,2.675686391,1.421885511,5.39764681,0.00522388,DB0083610047571_,5.254514873,0.984205942,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,loperamide,DB00836
,24455,DB00005,10016807,121,127961,32,42387,0.303130846,1.252526949,0.84226228,1.912099386,0.469577693,DB0000510016807_,0.755921513,0.22516307,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,etanercept,DB00005
,24456,DB08827,10047895,234,928,165,417,0.000172838,0.637414784,0.503159581,0.808459276,0.001275957,DB0882710047895_,6.664058761,-0.450334684,NA,10047895,Weight decreased,10022891,Investigations,Inv,lomitapide,DB08827
,24473,DB00213,10007559,201,18694,155,13266,0.449255469,0.920245188,0.741650984,1.143590829,0.616834517,DB0021310007559_,0.483154496,-0.083115136,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,24477,DB00635,10007559,200,32853,159,23635,0.361757105,0.904929412,0.730607657,1.1223588,0.531514003,DB0063510007559_,0.632025736,-0.099898336,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,prednisone,DB00635
,24479,DB00927,10007559,56,7441,44,4972,0.473461665,0.850438616,0.561789542,1.294522528,0.639398867,DB0092710007559_,0.447226814,-0.162003044,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,famotidine,DB00927
,24484,DB00588,10011078,32,16492,33,8435,0.005508485,0.495962409,0.295066597,0.832778659,0.02210629,DB0058810011078_,3.811893109,-0.701255143,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,fluticasone propionate,DB00588
,24485,DB00635,10011078,37,33016,45,23749,0.018549413,0.591458429,0.372101713,0.934869221,0.058231377,DB0063510011078_,2.843330952,-0.525163879,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,prednisone,DB00635
,24493,DB00588,10028596,111,16413,66,8402,0.339660525,0.860954826,0.628437461,1.187398066,0.508745621,DB0058810028596_,0.675807149,-0.149713243,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,fluticasone propionate,DB00588
,24494,DB00635,10028596,139,32914,151,23643,0.000517152,0.661259296,0.521039745,0.838666976,0.003173788,DB0063510028596_,5.752829501,-0.413609238,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,prednisone,DB00635
,24496,DB00927,10028596,40,7457,63,4953,1.74716013072863e-05,0.421746197,0.275969931,0.637875506,0.000177211,DB0092710028596_,8.638172202,-0.863351575,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,famotidine,DB00927
,24499,DB08908,10061284,42,10631,15,3264,0.638665861,0.859711585,0.466321282,1.671210092,0.775808496,DB0890810061284_,0.253849572,-0.151158313,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,dimethyl fumarate,DB08908
,24500,DB00563,10001760,1644,45002,61,15287,4.20802760919163e-130,9.154969124,7.083342604,12.03033677,1.22897784119558e-126,DB0056310001760_,289.9195389,2.214296806,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,24501,DB00563,10005911,30,46616,21,15327,0.009162344,0.469698977,0.260007942,0.863477452,0.033193055,DB0056310005911_,3.405414615,-0.755663265,NA,10005911,Body temperature increased,10022891,Investigations,Inv,methotrexate,DB00563
,24502,DB00005,10012174,238,127844,64,42355,0.143142924,1.232021966,0.931096337,1.650483742,0.27423555,DB0000510012174_,1.293767869,0.208656695,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,etanercept,DB00005
,24503,DB00563,10012174,127,46519,94,15254,7.25077803764464e-09,0.443027644,0.336437586,0.585126317,1.67843857965204e-07,DB0056310012174_,15.60023171,-0.814123108,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,24509,DB00563,10020751,417,46229,76,15272,5.65859589051486e-07,1.812499678,1.415510255,2.347883887,8.66290630612554e-06,DB0056310020751_,11.65646029,0.59470693,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,methotrexate,DB00563
,24510,DB00563,10022998,40,46606,27,15321,0.006457637,0.487003411,0.291472654,0.825539508,0.025105604,DB0056310022998_,3.684664204,-0.719484152,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,24511,DB00563,10028735,161,46485,30,15318,0.003173137,1.768360747,1.191463736,2.70730749,0.014165406,DB0056310028735_,4.25695247,0.570052986,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,24512,DB00563,10042209,176,46470,31,15317,0.000882696,1.871223892,1.271413577,2.83860361,0.004971428,DB0056310042209_,5.304048077,0.626592704,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,24513,DB00563,10047571,178,46468,37,15311,0.008948072,1.585080473,1.106753112,2.325307597,0.032562655,DB0056310047571_,3.424589186,0.460635178,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,methotrexate,DB00563
,24515,DB00216,10019211,77,846,12,96,0.363066183,0.728381926,0.376501644,1.524746816,0.532574062,DB0021610019211_,0.630033307,-0.316929745,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,eletriptan,DB00216
,24518,DB01240,10003658,105,5646,32,1544,0.599876037,0.897314125,0.596278663,1.383789497,0.744446148,DB0124010003658_,0.295114763,-0.108349283,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,epoprostenol,DB01240
,24519,DB00820,10007598,50,11865,26,5790,0.807042508,0.938446501,0.572469812,1.572346779,0.895729434,DB0082010007598_,0.110116882,-0.063529429,NA,10007598,Cardiac pacemaker insertion,10042613,Surgical and medical procedures,Surg,tadalafil,DB00820
,24522,DB01240,10016825,738,5013,141,1435,1.7433718832941e-05,1.498243261,1.237194914,1.824088887,0.000176895,DB0124010016825_,8.639956836,0.404293263,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,epoprostenol,DB01240
,24523,DB06228,10016825,79,15833,39,16037,0.000198945,2.051684037,1.380161771,3.095277383,0.001433855,DB0622810016825_,6.547388678,0.718660937,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,rivaroxaban,DB06228
,24524,DB00820,10030095,394,11521,160,5656,0.048000738,1.208874262,1.000550883,1.4660997,0.121352254,DB0082010030095_,2.109057771,0.189689565,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,24525,DB06228,10030095,128,15784,74,16002,9.80593156877197e-05,1.753577872,1.305802967,2.369583848,0.000783781,DB0622810030095_,7.151380373,0.561658199,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,24529,DB00338,10016100,56,33618,41,22231,0.678167192,0.903218398,0.592783425,1.386586535,0.805023016,DB0033810016100_,0.216884411,-0.101790897,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,24530,DB00722,10016100,37,25366,34,25998,0.721916215,1.115346071,0.680805219,1.832440297,0.836155498,DB0072210016100_,0.178940681,0.109164734,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,24532,DB08827,10028813,178,984,50,532,6.18406956574883e-05,1.924048053,1.372093352,2.7369738,0.000529042,DB0882710028813_,7.544442033,0.654431328,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lomitapide,DB08827
,24539,DB00853,10043554,44,1777,42,2224,0.228542545,1.311047234,0.835128155,2.060829793,0.38409468,DB0085310043554_,0.956866195,0.270826233,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,temozolomide,DB00853
,24540,DB05676,10000081,468,46661,250,25079,0.968633354,1.006148313,0.860421527,1.178807119,1,DB0567610000081_,0,0.006129489,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,24541,DB05676,10025482,913,46216,341,24988,3.67100149697004e-09,1.44761602,1.275670628,1.645770669,9.06882277705427e-08,DB0567610025482_,16.21583828,0.369918079,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,24542,DB05676,10028334,530,46599,189,25140,6.81980137513887e-07,1.512865534,1.278085694,1.797042494,1.02141583558704e-05,DB0567610028334_,11.49173573,0.414005557,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,24546,DB05676,10017367,349,46780,247,25082,0.001030207,0.757609292,0.641327452,0.895994685,0.00564616,DB0567610017367_,5.176779523,-0.277587471,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,24548,DB05676,10033371,1153,45976,457,24872,1.47479452469973e-08,1.364868519,1.222230267,1.52604952,3.18498274942008e-07,DB0567610033371_,14.95964878,0.311058101,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,24549,DB05679,10033371,112,6819,52,4857,0.01059554,1.53407502,1.09216929,2.179307127,0.037272989,DB0567910033371_,3.289486377,0.427927606,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,24550,DB05676,10040831,87,47042,41,25288,0.517220993,1.140667872,0.778009915,1.696996364,0.676847247,DB0567610040831_,0.390309664,0.131613943,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,24553,DB00497,10024855,136,19131,122,16253,0.661473031,0.947027295,0.73550379,1.220526066,0.793526116,DB0049710024855_,0.231268828,-0.054427363,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,24555,DB00497,10031127,24,19243,34,16341,0.064180943,0.599445498,0.339935081,1.041489534,0.15097513,DB0049710031127_,1.89064016,-0.511750221,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,oxycodone,DB00497
,24557,DB08875,10053762,91,552,127,1116,0.012223581,1.448401865,1.072944091,1.94961466,0.04177569,DB0887510053762_,3.175440686,0.370460786,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cabozantinib,DB08875
,24558,DB05676,10061428,761,46368,419,24910,0.689159483,0.97570589,0.86401839,1.103038507,0.812512369,DB0567610061428_,0.207624142,-0.024594081,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,apremilast,DB05676
,24561,DB00619,10035598,29,2870,32,2462,0.366681467,0.777457643,0.452359384,1.331066156,0.536320871,DB0061910035598_,0.623022658,-0.251726115,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,imatinib,DB00619
,24562,DB00619,10061822,50,2849,32,2462,0.219485638,1.350177897,0.846339809,2.182187752,0.372850897,DB0061910061822_,0.98657668,0.300236359,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,24572,DB00047,10047895,152,9133,196,8322,0.001636409,0.706664423,0.566741971,0.879794734,0.00824794,DB0004710047895_,4.79779183,-0.347199375,NA,10047895,Weight decreased,10022891,Investigations,Inv,insulin glargine,DB00047
,24573,DB00230,10047895,430,19244,170,8481,0.244304285,1.114726219,0.929423688,1.34182392,0.402884852,DB0023010047895_,0.909104485,0.108608831,NA,10047895,Weight decreased,10022891,Investigations,Inv,pregabalin,DB00230
,24574,DB00395,10047895,48,2136,13,723,0.552808038,1.249682968,0.661754884,2.529130372,0.706536098,DB0039510047895_,0.347380985,0.222889893,NA,10047895,Weight decreased,10022891,Investigations,Inv,carisoprodol,DB00395
,24575,DB01224,10047895,97,8011,74,5843,0.815304563,0.956043634,0.697812891,1.314495846,0.900924052,DB0122410047895_,0.104334318,-0.044951724,NA,10047895,Weight decreased,10022891,Investigations,Inv,quetiapine,DB01224
,24576,DB01306,10047895,66,4142,78,3788,0.130594275,0.773864297,0.547242577,1.091506769,0.256619484,DB0130610047895_,1.360160897,-0.256358747,NA,10047895,Weight decreased,10022891,Investigations,Inv,insulin aspart,DB01306
,24587,DB00047,10061428,117,9168,142,8376,0.024132625,0.752781019,0.583182449,0.970161786,0.071545912,DB0004710061428_,2.637415912,-0.283980904,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,insulin glargine,DB00047
,24588,DB00230,10061428,215,19459,84,8567,0.37722733,1.126844412,0.870543688,1.469954928,0.547124941,DB0023010061428_,0.603078092,0.11942117,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,pregabalin,DB00230
,24590,DB00736,10061428,168,10423,121,5432,0.008566839,0.723572011,0.568011158,0.924051857,0.031454025,DB0073610061428_,3.459228325,-0.323555207,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,esomeprazole,DB00736
,24591,DB01098,10061428,110,8039,115,7094,0.225795596,0.844091795,0.642663387,1.108221468,0.380646308,DB0109810061428_,0.96588466,-0.169494028,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,rosuvastatin,DB01098
,24592,DB01224,10061428,81,8027,70,5847,0.320330135,0.842895899,0.603419027,1.179909993,0.488519486,DB0122410061428_,0.716375918,-0.170911818,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,quetiapine,DB01224
,24595,DB01104,10017944,81,15382,23,7263,0.034553676,1.662844395,1.034723942,2.771898814,0.094529909,DB0110410017944_,2.358839,0.508529627,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,24596,DB00108,10037660,161,10033,48,3247,0.685073991,1.085508735,0.779877925,1.535249205,0.809820555,DB0010810037660_,0.210942593,0.082048758,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,24597,DB01164,10012174,184,6340,258,7678,0.145260606,0.863697207,0.708808039,1.050773165,0.277413087,DB0116410012174_,1.282247595,-0.146533026,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,calcium chloride,DB01164
,24600,DB00005,10022078,246,127836,21,42398,8.98135432345236e-13,3.885230963,2.48537279,6.390453706,4.05626973182037e-11,DB0000510022078_,23.92817226,1.357182432,female,10022078,Injection site inflammation,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,24604,DB00186,10042727,40,16861,11,9997,0.020300883,2.155966091,1.085039151,4.661588266,0.062542044,DB0018610042727_,2.771916245,0.768238925,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,24606,DB00451,10042727,110,47161,16,15403,0.001244036,2.245236602,1.322294702,4.067337405,0.006586002,DB0045110042727_,5.022808825,0.808810906,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,24608,DB01075,10042727,67,19881,29,11068,0.286808772,1.286211404,0.819821514,2.064214899,0.451599041,DB0107510042727_,0.794960571,0.251701001,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,24623,DB06186,10012735,179,2030,280,3366,0.581192353,1.060006489,0.866600128,1.294011999,0.729571902,DB0618610012735_,0.315297352,0.05827503,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ipilimumab,DB06186
,24624,DB06186,10047895,27,2182,51,3595,0.638608527,0.87224123,0.524248199,1.422055878,0.775774702,DB0618610047895_,0.253893133,-0.136689254,NA,10047895,Weight decreased,10022891,Investigations,Inv,ipilimumab,DB06186
,24627,DB08827,10000081,34,1128,19,563,0.767527739,0.893213494,0.490121144,1.673506399,0.872315063,DB0882710000081_,0.136604609,-0.112929651,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,lomitapide,DB08827
,24633,DB14726,10053762,38,1979,35,2813,0.072441609,1.543085107,0.945326521,2.525546066,0.165561925,DB1472610053762_,1.798409985,0.433783729,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,dabigatran,DB14726
,24636,DB14512,10064355,119,4725,63,2349,0.690826195,0.93905676,0.683289984,1.300947159,0.81351044,DB1451210064355_,0.206396518,-0.062879354,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,mometasone furoate,DB14512
,24637,DB00736,10008479,175,10416,86,5467,0.646078184,1.068041154,0.81862352,1.402184463,0.781649463,DB0073610008479_,0.246348896,0.065826274,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,24638,DB08932,10008479,1030,18413,254,6343,1.76357601863703e-06,1.396865198,1.212755541,1.613715959,2.37052394016233e-05,DB0893210008479_,10.64981446,0.334230582,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,24639,DB14513,10008479,101,7076,40,3524,0.242341082,1.257435372,0.86173215,1.86621661,0.400564311,DB1451310008479_,0.914880948,0.229074227,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,24640,DB14726,10008479,33,1984,34,2814,0.212249231,1.376516783,0.823270925,2.299053329,0.364067543,DB1472610008479_,1.010415871,0.319556238,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,dabigatran,DB14726
,24641,DB00736,10012174,136,10455,80,5473,0.427840685,0.889929283,0.668888578,1.190546568,0.596356484,DB0073610012174_,0.516916663,-0.116613277,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,esomeprazole,DB00736
,24642,DB00761,10012174,338,14969,203,8422,0.468934388,0.936795173,0.783139366,1.122806576,0.635342473,DB0076110012174_,0.453591098,-0.06529062,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,24643,DB08932,10012174,386,19057,105,6492,0.046367941,1.252317999,1.004855793,1.572022191,0.118221285,DB0893210012174_,2.135197113,0.224996233,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,macitentan,DB08932
,24645,DB14513,10013968,325,6852,142,3422,0.209037814,1.143034271,0.93140795,1.408246274,0.36006284,DB1451310013968_,1.021476706,0.133686368,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium,DB14513
,24646,DB00169,10013971,184,38507,112,18063,0.033458673,0.770671412,0.605578444,0.984299643,0.092259241,DB0016910013971_,2.383152825,-0.260493181,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,24647,DB00203,10013971,649,13229,218,8720,8.13990457470429e-19,1.962292896,1.676453797,2.303733831,7.57371298216291e-17,DB0020310013971_,37.11926315,0.674113635,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,24648,DB00736,10013971,49,10542,32,5521,0.348917406,0.801966008,0.50273977,1.295493354,0.518430458,DB0073610013971_,0.656949382,-0.220689057,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,24649,DB08932,10013971,1020,18423,320,6277,0.220408355,1.086026097,0.953702449,1.239299752,0.373950854,DB0893210013971_,0.983630897,0.082525252,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,24652,DB00736,10016256,714,9877,329,5224,0.046751689,1.147853473,1.001449603,1.317652807,0.118989896,DB0073610016256_,2.128716695,0.137893653,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,24653,DB14726,10016256,64,1953,73,2775,0.218476761,1.245645385,0.871728423,1.776284092,0.371678893,DB1472610016256_,0.989724988,0.219653777,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dabigatran,DB14726
,24654,DB00169,10035664,1204,37487,886,17289,2.54128035658734e-24,0.626730628,0.573081381,0.685607179,3.72131221018932e-22,DB0016910035664_,49.3427957,-0.467238452,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,24655,DB14513,10035664,275,6902,182,3382,0.002307806,0.740381919,0.608853412,0.90204635,0.01092887,DB1451310035664_,4.516347362,-0.30058912,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,magnesium,DB14513
,24656,DB14726,10035664,73,1944,73,2775,0.040317739,1.4273352,1.01205383,2.013004689,0.10626553,DB1472610035664_,2.241814316,0.355809209,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,dabigatran,DB14726
,24657,DB00169,10037400,124,38567,56,18119,0.872868592,1.040268854,0.75248917,1.453751904,0.944501202,DB0016910037400_,0.05709832,0.039479194,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,24659,DB00761,10037400,180,15127,73,8552,0.017651967,1.393987077,1.054902312,1.858160675,0.056037345,DB0076110037400_,2.881736942,0.332168042,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,24662,DB00169,10058267,32,38659,19,18156,0.452957217,0.791009597,0.434774746,1.477402185,0.620556485,DB0016910058267_,0.477138648,-0.234445178,NA,10058267,Troponin increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,24664,DB00695,10058267,45,28004,32,20496,1,1.029230031,0.639505501,1.674083203,1,DB0069510058267_,0,0.02881098,NA,10058267,Troponin increased,10022891,Investigations,Inv,furosemide,DB00695
,24671,DB00005,10030338,50,128032,8,42411,0.049213124,2.070197545,0.973767084,5.05667907,0.12350267,DB0000510030338_,2.091492504,0.727644035,NA,10030338,Onychomycosis,10021881,Infections and infestations,Infec,etanercept,DB00005
,24672,DB08820,10028813,105,4296,53,3492,0.00461609,1.61026465,1.142927847,2.292028458,0.019175651,DB0882010028813_,3.954113982,0.476398544,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ivacaftor,DB08820
,24673,DB00215,10047895,209,10894,96,5180,0.80488757,1.035158632,0.807175974,1.335415708,0.894427482,DB0021510047895_,0.11157145,0.034554682,NA,10047895,Weight decreased,10022891,Investigations,Inv,citalopram,DB00215
,24674,DB08820,10047895,62,4339,47,3498,0.771913421,1.063474392,0.714199023,1.592683825,0.875159166,DB0882010047895_,0.133349505,0.061541277,NA,10047895,Weight decreased,10022891,Investigations,Inv,ivacaftor,DB08820
,24679,DB08827,10016256,53,1109,30,552,0.633462125,0.879422526,0.54466753,1.443029013,0.772036715,DB0882710016256_,0.258723172,-0.128489807,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lomitapide,DB08827
,24683,DB01050,10005750,155,17953,67,9304,0.227410881,1.198885698,0.893541163,1.623485446,0.382637321,DB0105010005750_,0.960667682,0.18139254,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,ibuprofen,DB01050
,24684,DB01050,10013700,1430,16678,415,8956,3.1619157134374e-29,1.850327426,1.652481351,2.075162335,6.7024963328792e-27,DB0105010013700_,60.26731747,0.61536261,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ibuprofen,DB01050
,24685,DB00005,10039737,167,127915,69,42350,0.131544551,0.801301408,0.601702626,1.077045947,0.25795647,DB0000510039737_,1.354964428,-0.221518114,NA,10039737,Scratch,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,24686,DB00656,10006093,60,11953,50,6569,0.035413168,0.659470283,0.444998213,0.981116887,0.096314877,DB0065610006093_,2.340132489,-0.416318367,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,trazodone,DB00656
,24687,DB01075,10006093,54,19894,48,11049,0.02229403,0.624799786,0.41531441,0.942463215,0.067282689,DB0107510006093_,2.698852304,-0.470324023,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,24688,DB00656,10008479,143,11870,70,6549,0.429319355,1.12710944,0.839617268,1.524951617,0.597831069,DB0065610008479_,0.514447059,0.119656338,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,24689,DB00656,10013573,389,11624,198,6421,0.380847037,1.085259058,0.909672732,1.297918082,0.550878515,DB0065610013573_,0.596240975,0.081818721,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,24690,DB00656,10018884,56,11957,47,6572,0.03844854,0.654873411,0.435931845,0.987745165,0.102538542,DB0065610018884_,2.277516535,-0.423313327,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,trazodone,DB00656
,24691,DB01075,10018884,140,19808,81,11016,0.778476392,0.96125225,0.725191766,1.281155957,0.879245519,DB0107510018884_,0.128691104,-0.039518418,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,diphenhydramine,DB01075
,24692,DB00656,10022523,76,11937,116,6503,1.93026744946467e-12,0.356943093,0.263285708,0.481581993,8.28360488313122e-11,DB0065610022523_,23.21415778,-1.030178912,male,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,24696,DB00656,10041349,235,11778,109,6510,0.139467947,1.191614983,0.943528456,1.512769688,0.269067855,DB0065610041349_,1.312791683,0.175309516,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,24697,DB01075,10041349,260,19688,124,10973,0.16372701,1.168647839,0.938735935,1.46122304,0.302386485,DB0107510041349_,1.19604933,0.155847387,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,24698,DB00190,10001488,28,3269,99,4575,4.51171277240724e-06,0.395866257,0.249834804,0.609112377,5.4064449611454e-05,DB0019010001488_,9.825333712,-0.92667886,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,24700,DB00190,10002855,111,3186,97,4577,0.000451463,1.643793215,1.235621878,2.189939107,0.002837228,DB0019010002855_,5.864927606,0.497006507,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,24702,DB00190,10019063,377,2920,761,3913,9.14627327207771e-10,0.663906424,0.579921689,0.759195389,2.5602746853734e-08,DB0019010019063_,17.48056619,-0.409614067,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,24711,DB00402,10012378,42,1310,14,682,0.197247756,1.561517343,0.828925937,3.118510038,0.345688097,DB0040210012378_,1.062218364,0.445658004,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,eszopiclone,DB00402
,24712,DB00482,10012378,171,8088,38,3033,0.002785128,1.687472728,1.178222213,2.472276683,0.012722815,DB0048210012378_,4.364358424,0.523231982,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,celecoxib,DB00482
,24713,DB00402,10012735,55,1297,20,676,0.21386787,1.433070265,0.837075387,2.546526508,0.36606759,DB0040210012735_,1.004937289,0.359819181,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,eszopiclone,DB00402
,24714,DB00482,10012735,364,7895,125,2946,0.466592448,1.086596742,0.88030598,1.348349112,0.633314071,DB0048210012735_,0.456788818,0.083050556,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,celecoxib,DB00482
,24715,DB00482,10042609,57,8202,14,3057,0.181327827,1.517361109,0.833337767,2.95331597,0.325539927,DB0048210042609_,1.122270161,0.416972714,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,celecoxib,DB00482
,24722,DB00959,10017955,46,8032,42,4960,0.07776899,0.676384999,0.434678369,1.054908791,0.174580059,DB0095910017955_,1.74537185,-0.390992841,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,24727,DB00126,10005557,63,10108,42,5903,0.542906851,0.876000624,0.582718961,1.328792652,0.698118538,DB0012610005557_,0.359366365,-0.132388476,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,ascorbic acid,DB00126
,24728,DB00181,10005557,57,9799,24,5847,0.167537394,1.417117008,0.864343637,2.390608849,0.307586813,DB0018110005557_,1.178997913,0.348624532,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,baclofen,DB00181
,24730,DB00281,10005557,46,11412,22,5649,1,1.034987024,0.609400268,1.808439632,1,DB0028110005557_,0,0.03438889,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,lidocaine,DB00281
,24735,DB00736,10005557,53,10538,42,5511,0.05077373,0.659926443,0.431282651,1.015527073,0.12644725,DB0073610005557_,2.067930053,-0.4156269,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,esomeprazole,DB00736
,24737,DB01104,10005557,61,15402,50,7236,0.004161671,0.573171634,0.387467717,0.851402036,0.017640628,DB0110410005557_,4.037550624,-0.556570072,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,sertraline,DB01104
,24739,DB06228,10005557,48,15864,38,16038,0.281028529,1.276999417,0.816508461,2.009893769,0.444956016,DB0622810005557_,0.809779841,0.24451312,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,rivaroxaban,DB06228
,24741,DB00181,10009346,23,9833,38,5833,8.96966614897383e-05,0.359069683,0.204015873,0.619077658,0.000727903,DB0018110009346_,7.225343214,-1.024238807,male,10009346,Clonus,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,24757,DB00126,10010774,312,9859,160,5785,0.175538328,1.144226705,0.939918995,1.397200964,0.318044111,DB0012610010774_,1.145565192,0.134729042,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,24759,DB00281,10010774,168,11290,81,5590,0.892163019,1.026932184,0.781559766,1.358564679,0.955096007,DB0028110010774_,0.045943412,0.026575896,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,24761,DB00588,10010774,323,16201,159,8309,0.697663941,1.041867361,0.857354634,1.270153976,0.818226695,DB0058810010774_,0.200615848,0.041014643,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,24764,DB00736,10010774,231,10360,94,5459,0.038816792,1.294909632,1.01209845,1.667758676,0.103276696,DB0073610010774_,2.270343525,0.25844091,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,24765,DB01062,10010774,91,4395,46,1699,0.149152864,0.764772041,0.528220264,1.120449788,0.282812121,DB0106210010774_,1.262972485,-0.268177475,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,oxybutynin,DB01062
,24766,DB01104,10010774,235,15228,103,7183,0.55746735,1.076196795,0.848625971,1.372651374,0.710536031,DB0110410010774_,0.341735621,0.07343334,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,24767,DB01225,10010774,95,4949,56,4584,0.008417469,1.57123462,1.114749233,2.232445116,0.031016074,DB0122510010774_,3.473249703,0.451861692,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,24768,DB06228,10010774,175,15737,110,15966,8.09935956012656e-05,1.614025154,1.263036724,2.070029948,0.000666223,DB0622810010774_,7.313885609,0.478731155,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,24769,DB11089,10010774,444,9731,337,8070,0.239923029,1.092650859,0.943229287,1.266554109,0.397790824,DB1108910010774_,0.92182898,0.088606725,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,24770,DB00126,10017577,179,9992,68,5877,0.002173241,1.548232381,1.162463454,2.082289052,0.010420221,DB0012610017577_,4.564007052,0.437113881,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,24772,DB00281,10017577,100,11358,31,5640,0.019927728,1.601786244,1.059645139,2.483679871,0.06158734,DB0028110017577_,2.787298953,0.471119409,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,24774,DB00588,10017577,214,16310,76,8392,0.00496846,1.448790589,1.108613631,1.910552534,0.020356308,DB0058810017577_,3.894364436,0.370729132,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,24776,DB00646,10017577,64,3389,20,1980,0.016035186,1.869382186,1.112550813,3.27173127,0.051903806,DB0064610017577_,2.95836316,0.625607994,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,24778,DB01104,10017577,243,15220,71,7215,0.000247601,1.622412016,1.238680556,2.147845644,0.001721063,DB0110410017577_,6.364813396,0.483913941,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,24779,DB01225,10017577,41,5003,30,4610,0.343615938,1.259279333,0.765908717,2.092360218,0.512893885,DB0122510017577_,0.667686306,0.2305396,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,24780,DB11089,10017577,160,10015,104,8303,0.061549003,1.27545349,0.988443479,1.651671195,0.146302726,DB1108910017577_,1.92207734,0.243301794,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,24797,DB00126,10028334,197,9974,81,5864,0.006938565,1.429870004,1.096134943,1.879557681,0.02661513,DB0012610028334_,3.626275416,0.357583534,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,24799,DB00281,10028334,132,11326,47,5624,0.055104867,1.394562474,0.990948691,1.992482747,0.134537564,DB0028110028334_,2.00591183,0.332580728,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,lidocaine,DB00281
,24801,DB00588,10028334,262,16262,113,8355,0.124139927,1.191198372,0.950252844,1.501114668,0.247292003,DB0058810028334_,1.397185442,0.174959836,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,24803,DB00646,10028334,57,3396,31,1969,0.824168006,1.066077535,0.674121735,1.714684288,0.906856118,DB0064610028334_,0.097771477,0.063986057,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,nystatin,DB00646
,24805,DB00736,10028334,178,10413,86,5467,0.557014803,1.086664911,0.833583109,1.425609092,0.710217516,DB0073610028334_,0.342183995,0.083113291,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,24806,DB00904,10028334,318,22751,156,14300,0.01177695,1.281239397,1.053323092,1.563826155,0.040569941,DB0090410028334_,3.204727865,0.247827888,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,24807,DB01225,10028334,67,4977,33,4607,0.003324949,1.879240519,1.218473115,2.949836202,0.014699568,DB0122510028334_,4.219937146,0.630867716,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,enoxaparin,DB01225
,24808,DB06228,10028334,135,15777,96,15980,0.008214263,1.42432142,1.087219696,1.871875043,0.030429412,DB0622810028334_,3.492345625,0.353695504,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,rivaroxaban,DB06228
,24812,DB00316,10028335,56,65418,59,36894,0.000896306,0.535281917,0.364548855,0.785254954,0.005034063,DB0031610028335_,5.291527887,-0.624961724,NA,10028335,Muscle spasticity,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,24823,DB11089,10028335,20,10155,36,8371,0.004573414,0.457972916,0.251014943,0.813302671,0.019013394,DB1108910028335_,3.96261159,-0.780945231,NA,10028335,Muscle spasticity,10029205,Nervous system disorders,Nerv,docusate,DB11089
,24828,DB00316,10037032,32,65442,29,36924,0.081935527,0.622566418,0.364735148,1.066897268,0.181606824,DB0031610037032_,1.705911235,-0.473904961,NA,10037032,Proteinuria,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,24855,DB06228,10037063,49,15863,43,16033,0.531859207,1.151741,0.748525421,1.777995752,0.688733828,DB0622810037063_,0.372900398,0.141274711,NA,10037063,Prothrombin time prolonged,10022891,Investigations,Inv,rivaroxaban,DB06228
,24894,DB00316,10043414,128,65346,83,36870,0.350894138,0.870139925,0.654809611,1.161594404,0.520617094,DB0031610043414_,0.652740453,-0.139101247,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,24896,DB00588,10043414,47,16477,16,8452,0.182632394,1.5067894,0.838465217,2.848716657,0.327231935,DB0058810043414_,1.117086079,0.409981162,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,24902,DB01104,10043414,55,15408,25,7261,1,1.036723121,0.634649237,1.737815769,1,DB0110410043414_,0,0.036064893,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,24906,DB00126,10046571,325,9846,105,5840,2.81348220004757e-08,1.835825833,1.465171867,2.315665063,5.70840444834043e-07,DB0012610046571_,14.3761561,0.607494425,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,24907,DB00211,10046571,44,1392,34,1597,0.107044501,1.484496521,0.921581075,2.409693026,0.221693206,DB0021110046571_,1.506460807,0.395075671,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,midodrine,DB00211
,24908,DB00281,10046571,291,11167,60,5611,1.25228538292443e-11,2.436835837,1.836354791,3.280065946,4.70569282203984e-10,DB0028110046571_,21.47707792,0.89070041,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,lidocaine,DB00281
,24909,DB00535,10046571,53,1151,6,640,1.92440607258749e-05,4.908352006,2.095837884,14.05352432,0.000193065,DB0053510046571_,8.552483962,1.590938245,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,cefdinir,DB00535
,24910,DB00588,10046571,413,16111,75,8393,1.87258748785761e-20,2.86858393,2.234786951,3.724766218,2.02139474818634e-18,DB0058810046571_,40.74274393,1.053818504,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,24912,DB00646,10046571,142,3311,54,1946,0.006546057,1.54541618,1.116048189,2.16645784,0.025385528,DB0064610046571_,3.673576044,0.435293246,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,nystatin,DB00646
,24913,DB00687,10046571,37,949,33,1052,0.395623105,1.242768376,0.749408872,2.068725279,0.565283394,DB0068710046571_,0.570428091,0.217341452,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,fludrocortisone,DB00687
,24914,DB01062,10046571,285,4201,95,1650,0.194600988,1.178249795,0.924048983,1.513026131,0.342512855,DB0106210046571_,1.071446089,0.164030113,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,oxybutynin,DB01062
,24915,DB01225,10046571,118,4926,52,4588,4.1425953014116e-06,2.113362971,1.508647896,2.995768562,5.00519960917508e-05,DB0122510046571_,9.902448171,0.748280504,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,enoxaparin,DB01225
,24916,DB06228,10046571,207,15705,96,15980,6.28109445607828e-11,2.193943273,1.712372632,2.82770027,2.1193654400259e-09,DB0622810046571_,19.97214911,0.785700506,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,24917,DB11089,10046571,372,9803,176,8231,2.82226301048829e-10,1.774637404,1.475713835,2.140689539,8.59596561189856e-09,DB1108910046571_,18.57197286,0.573596123,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,docusate,DB11089
,24935,DB00126,10051055,72,10099,52,5893,0.262315205,0.807977266,0.556876058,1.179266156,0.424070063,DB0012610051055_,0.857856594,-0.213221357,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,ascorbic acid,DB00126
,24936,DB00181,10051055,41,9815,43,5828,0.012331823,0.566213744,0.359502794,0.89058918,0.042066311,DB0018110051055_,3.168508083,-0.568783632,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,baclofen,DB00181
,24942,DB00736,10051055,56,10535,46,5507,0.027644673,0.636368744,0.422530415,0.962683498,0.079440279,DB0073610051055_,2.532749751,-0.451977097,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,esomeprazole,DB00736
,24944,DB01104,10051055,68,15395,39,7247,0.350016319,0.820798074,0.545158277,1.251234392,0.519607982,DB0110410051055_,0.654680632,-0.19747815,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,sertraline,DB01104
,24945,DB01225,10051055,142,4902,163,4477,0.05450567,0.795657764,0.628456301,1.00644178,0.133458923,DB0122510051055_,2.013961539,-0.22858613,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,enoxaparin,DB01225
,24983,DB00316,10057362,142,65332,89,36864,0.450837433,0.900277737,0.685640801,1.187407151,0.618505803,DB0031610057362_,0.480448705,-0.105051967,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,24985,DB00588,10057362,65,16459,24,8444,0.179524052,1.38944538,0.857368641,2.322623402,0.323260127,DB0058810057362_,1.129297932,0.32890466,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,24990,DB00904,10057362,45,23024,12,14444,0.00617452,2.352490034,1.223408625,4.886999462,0.024216716,DB0090410057362_,3.720712153,0.855474356,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,24992,DB01104,10057362,39,15424,24,7262,0.343639879,0.76507011,0.448287979,1.331090118,0.512893885,DB0110410057362_,0.667686306,-0.267787803,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,24994,DB06228,10057362,36,15876,20,16056,0.032226609,1.820363154,1.025449534,3.320288235,0.089585578,DB0622810057362_,2.412560936,0.599036016,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,24995,DB11089,10057362,31,10144,27,8380,0.895175697,0.948463758,0.547354778,1.653167854,0.956064085,DB1108910057362_,0.044930333,-0.0529117,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,25000,DB00635,10042772,210,32843,134,23660,0.297663787,1.129016854,0.904104405,1.413802103,0.463567522,DB0063510042772_,0.768803227,0.121347214,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,25004,DB00115,10003246,124,18301,33,10439,4.06542795799855e-05,2.143290969,1.448676873,3.252243553,0.000369885,DB0011510003246_,7.902318436,0.762342484,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,25005,DB00153,10003246,66,7357,15,3424,0.011294154,2.047675038,1.154243037,3.869028809,0.039208345,DB0015310003246_,3.238865662,0.716705022,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,25006,DB00338,10003246,236,33438,64,22208,1.2939217402714e-11,2.44902071,1.849701622,3.282889952,4.83794209715986e-10,DB0033810003246_,21.44936149,0.895688234,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,25007,DB01373,10003246,218,22502,28,7353,3.14421043526304e-07,2.544215549,1.710062835,3.921492458,5.10000439931435e-06,DB0137310003246_,12.18626916,0.93382237,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,25008,DB00115,10011781,82,18343,20,10452,0.000393894,2.336152561,1.418382914,4.024898772,0.00253049,DB0011510011781_,5.979342311,0.848505371,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,25010,DB00338,10011781,141,33533,38,22234,1.44987554708567e-07,2.460209239,1.708116617,3.620965625,2.54575676387086e-06,DB0033810011781_,12.8810826,0.900246403,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,omeprazole,DB00338
,25011,DB00115,10015150,188,18237,71,10401,0.002777202,1.510133215,1.142185592,2.01556386,0.012692124,DB0011510015150_,4.366773612,0.412197869,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,25012,DB00153,10015150,89,7334,18,3421,0.000743594,2.306225343,1.37611196,4.074815805,0.004302777,DB0015310015150_,5.448494725,0.835612137,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,ergocalciferol,DB00153
,25013,DB01373,10015150,224,22496,39,7342,0.000167061,1.87439706,1.327934833,2.708982761,0.001238006,DB0137310015150_,6.694253222,0.62828704,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,25014,DB00115,10021789,177,18248,94,10378,0.612081522,1.070891613,0.828229051,1.392001575,0.754004115,DB0011510021789_,0.282357453,0.068491585,NA,10021789,Infection,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,25015,DB00153,10021789,86,7337,47,3392,0.350126827,0.845963424,0.584646055,1.237271109,0.519742681,DB0015310021789_,0.654421434,-0.167279154,NA,10021789,Infection,10021881,Infections and infestations,Infec,ergocalciferol,DB00153
,25016,DB00338,10021789,365,33309,187,22085,0.004468682,1.294150953,1.081150928,1.553292429,0.018671006,DB0033810021789_,3.980783437,0.257854846,NA,10021789,Infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,25017,DB00115,10023230,37,18388,15,10457,0.313137007,1.402743276,0.751076326,2.752548854,0.480701196,DB0011510023230_,0.732509416,0.338429802,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,25019,DB00338,10023230,62,33612,13,22259,4.3896831919335e-05,3.158266003,1.718091154,6.262657897,0.000395757,DB0033810023230_,7.834711304,1.150023144,female,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,25020,DB01373,10023230,51,22669,8,7373,0.049491709,2.073281379,0.976147737,5.06110995,0.124047829,DB0137310023230_,2.087088072,0.72913256,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,25021,DB00115,10028735,116,18309,38,10434,0.002419754,1.73961318,1.195582339,2.582141587,0.011363808,DB0011510028735_,4.477321667,0.553662778,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,25023,DB00338,10028735,231,33443,84,22188,1.09760926911542e-06,1.824484359,1.414580953,2.372375198,1.55329069549946e-05,DB0033810028735_,11.07254976,0.601297404,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,25024,DB00153,10028810,146,7277,50,3389,0.063127719,1.359882576,0.97726417,1.919580805,0.14918358,DB0015310028810_,1.902577648,0.307398355,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ergocalciferol,DB00153
,25025,DB01373,10037087,497,22223,93,7288,2.08135629060769e-07,1.752464363,1.399492772,2.214938515,3.51709740267587e-06,DB0137310037087_,12.55787451,0.561023005,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,25026,DB00115,10038683,50,18375,12,10460,0.005164733,2.371817444,1.24473338,4.895115329,0.020991018,DB0011510038683_,3.863660641,0.863656515,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,25028,DB00338,10038683,63,33611,35,22237,0.469904024,1.190842905,0.775407988,1.855875688,0.636179617,DB0033810038683_,0.452274338,0.17466138,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,25030,DB00115,10043521,52,18373,15,10457,0.021264126,1.97301113,1.093245189,3.775841653,0.064904785,DB0011510043521_,2.734833924,0.679560868,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,25032,DB00338,10043521,116,33558,33,22239,7.08589821150039e-06,2.329459215,1.569928812,3.542552596,8.02813941764172e-05,DB0033810043521_,9.429972668,0.845636144,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,25033,DB01373,10043521,51,22669,11,7370,0.239757833,1.507291001,0.775288402,3.208743875,0.397579625,DB0137310043521_,0.922360049,0.410314,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,25034,DB00005,10052136,41,128041,12,42407,0.873716167,1.131592884,0.583376547,2.365478248,0.945081962,DB0000510052136_,0.056483623,0.123626272,NA,10052136,Ear congestion,10013993,Ear and labyrinth disorders,Ear,etanercept,DB00005
,25039,DB00115,10052904,179,18246,48,10424,9.96914528700842e-07,2.130432963,1.539961203,2.997350561,1.42683900827126e-05,DB0011510052904_,11.15746395,0.756325228,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,25040,DB00153,10052904,60,7363,17,3422,0.084407678,1.640248424,0.942754559,3.003350867,0.185732606,DB0015310052904_,1.683447243,0.494847709,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,25041,DB00338,10052904,215,33459,82,22190,1.30325108618486e-05,1.738857685,1.341426811,2.272173129,0.000137073,DB0033810052904_,8.89499725,0.553228395,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,25047,DB00390,10012735,287,3858,156,3145,6.30054441080242e-05,1.499655452,1.222475536,1.845055024,0.00053691,DB0039010012735_,7.529680556,0.405235383,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,digoxin,DB00390
,25048,DB08827,10012735,300,862,156,426,0.685912504,0.950412392,0.754297085,1.199994539,0.810410849,DB0882710012735_,0.210213939,-0.050859292,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lomitapide,DB08827
,25049,DB00814,10028813,601,7686,149,3266,2.51301206843325e-09,1.713901927,1.423125362,2.074364326,6.44124607510308e-08,DB0081410028813_,16.55795873,0.5387726,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,25050,DB00814,10047700,248,8039,73,3342,0.010568684,1.412326667,1.080090789,1.865442266,0.037198429,DB0081410047700_,3.291488737,0.345238463,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,25051,DB08827,10047700,56,1106,21,561,0.267864619,1.35239925,0.796546479,2.376582052,0.430249718,DB0882710047700_,0.843389499,0.301880238,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lomitapide,DB08827
,25052,DB00390,10047895,117,4028,103,3198,0.449711073,0.901870291,0.683141365,1.192044454,0.617331082,DB0039010047895_,0.4823498,-0.10328457,NA,10047895,Weight decreased,10022891,Investigations,Inv,digoxin,DB00390
,25055,DB00927,10033645,31,7466,24,4992,0.584585377,0.863662068,0.48994092,1.539791625,0.732355822,DB0092710033645_,0.311488787,-0.146573711,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,25057,DB11089,10033645,41,10134,29,8378,0.549409087,1.168803537,0.708271321,1.9520045,0.703745906,DB1108910033645_,0.351337917,0.155980608,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,25059,DB01164,10038435,20,6504,36,7900,0.178991579,0.674817658,0.369754277,1.1986567,0.322654985,DB0116410038435_,1.131171685,-0.393312761,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,calcium chloride,DB01164
,25063,DB00254,10002855,121,5814,15,3373,2.8438992060748e-11,4.679202434,2.721778258,8.633785352,1.01289824704168e-09,DB0025410002855_,20.71045006,1.543127675,female,10002855,Anxiety,10037175,Psychiatric disorders,Psych,doxycycline,DB00254
,25064,DB00295,10002855,219,14444,106,9496,0.010105833,1.35826951,1.07062665,1.731910398,0.035875761,DB0029510002855_,3.327693386,0.30621147,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,morphine,DB00295
,25067,DB00916,10002855,101,5222,12,2419,3.17083407371938e-07,3.897981252,2.131405726,7.810154107,5.1381985012749e-06,DB0091610002855_,12.17880803,1.360458791,female,10002855,Anxiety,10037175,Psychiatric disorders,Psych,metronidazole,DB00916
,25068,DB00254,10012378,97,5838,31,3357,0.003977046,1.799169353,1.186819417,2.796535464,0.017000593,DB0025410012378_,4.074507052,0.587325088,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,doxycycline,DB00254
,25069,DB00295,10012378,168,14495,78,9524,0.012612152,1.415173569,1.074177186,1.878114227,0.042844643,DB0029510012378_,3.15017465,0.347252187,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,morphine,DB00295
,25072,DB00916,10012378,66,5257,16,2415,0.022352093,1.894836885,1.082274149,3.513564239,0.067419215,DB0091610012378_,2.696825208,0.639132758,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,metronidazole,DB00916
,25082,DB00295,10022116,42,14621,14,9588,0.028093693,1.96725126,1.052500028,3.902638817,0.080444765,DB0029510022116_,2.520184483,0.676637269,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,25086,DB01050,10022116,276,17832,15,9356,4.12226104603897e-33,9.653858025,5.74669468,17.49926985,1.12868366244932e-30,DB0105010022116_,68.95650074,2.267357631,female,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,25107,DB01050,10029223,40,18068,17,9354,0.576654586,1.21810454,0.674663303,2.292887008,0.725892715,DB0105010029223_,0.320353051,0.197295994,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,25110,DB00916,10033371,202,5121,36,2395,9.05663237618066e-09,2.623946408,1.826710599,3.865664048,2.05573041457607e-07,DB0091610033371_,15.39746443,0.964679447,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,25124,DB01050,10049119,145,17963,18,9353,1.88164891098341e-11,4.193898546,2.559799938,7.281276387,6.85504388429647e-10,DB0105010049119_,21.10086622,1.433630742,female,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,25139,DB00331,10005555,182,24764,133,20619,0.256804493,1.139359181,0.905369059,1.436894224,0.417678739,DB0033110005555_,0.87304271,0.130465983,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,metformin,DB00331
,25142,DB00331,10011469,65,24881,6,20746,2.11583963986011e-11,9.030206536,3.932182444,25.53372258,7.66044696056791e-10,DB0033110011469_,20.9897806,2.200575239,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,25143,DB00046,10013573,129,5330,96,4596,0.310496078,1.158683482,0.880058107,1.529836562,0.477916275,DB0004610013573_,0.738319719,0.147284431,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,insulin lispro,DB00046
,25144,DB00047,10013573,244,9041,213,8305,0.602086229,1.052297899,0.869833624,1.273827942,0.746220131,DB0004710013573_,0.292734641,0.050976249,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,25147,DB00047,10018484,137,9148,116,8402,0.527017672,1.084684421,0.839287289,1.403880211,0.684700245,DB0004710018484_,0.378774135,0.081289089,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,insulin glargine,DB00047
,25148,DB00331,10018484,243,24703,207,20545,0.812086498,0.976314456,0.806983101,1.182060657,0.89905753,DB0033110018484_,0.106408254,-0.023970555,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,metformin,DB00331
,25152,DB00046,10020993,106,5353,100,4592,0.525444292,0.909315965,0.683266127,1.210856883,0.683491029,DB0004610020993_,0.380541748,-0.095062649,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,insulin lispro,DB00046
,25153,DB00047,10020993,219,9066,228,8290,0.179619668,0.878317768,0.724490874,1.064590567,0.323387991,DB0004710020993_,1.128902467,-0.129746829,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,insulin glargine,DB00047
,25154,DB00046,10025482,170,5289,101,4591,0.002976225,1.460979536,1.131630596,1.894051257,0.013420841,DB0004610025482_,4.310946451,0.379107126,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,25155,DB00047,10025482,260,9025,179,8339,0.002691061,1.342081248,1.10252694,1.636582138,0.01237483,DB0004710025482_,4.392090724,0.294221579,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,25158,DB00331,10036653,40,24906,37,20715,0.648647494,0.899167447,0.560273581,1.446507192,0.783569988,DB0033110036653_,0.243894893,-0.106286003,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,metformin,DB00331
,25159,DB00046,10041349,49,5410,32,4660,0.263191279,1.318931903,0.826311946,2.131914052,0.424989727,DB0004610041349_,0.855690282,0.276822244,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,insulin lispro,DB00046
,25160,DB00047,10041349,81,9204,57,8461,0.124588378,1.306314931,0.918182712,1.869253084,0.247950447,DB0004710041349_,1.394526364,0.267210143,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,25161,DB00331,10042209,116,24830,35,20717,1.62686304215372e-08,2.765137242,1.879469486,4.161588981,3.47800691850431e-07,DB0033110042209_,14.87163625,1.017090269,female,10042209,Stress,10037175,Psychiatric disorders,Psych,metformin,DB00331
,25162,DB00046,10047571,97,5362,55,4637,0.013735121,1.525107471,1.08173562,2.168883293,0.045840237,DB0004610047571_,3.082593037,0.42206488,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,insulin lispro,DB00046
,25163,DB00047,10047571,118,9167,79,8439,0.031287611,1.375022417,1.023736728,1.855158619,0.087549353,DB0004710047571_,2.435552615,0.318470034,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,insulin glargine,DB00047
,25165,DB00108,10001949,55,10139,14,3281,0.484209055,1.271262835,0.696320227,2.478880095,0.648383046,DB0010810001949_,0.433273637,0.240010764,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,25166,DB00108,10027175,217,9977,80,3215,0.306193944,0.874106165,0.671178529,1.147789731,0.473135645,DB0010810027175_,0.748373156,-0.134553441,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,25167,DB00108,10028245,505,9689,158,3137,0.745670078,1.034851498,0.859721855,1.250923418,0.85479359,DB0010810028245_,0.156895254,0.034257936,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,25169,DB00811,10000081,51,2747,60,4096,0.241625806,1.267361019,0.852247609,1.878516345,0.399706367,DB0081110000081_,0.917025083,0.236936801,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ribavirin,DB00811
,25170,DB01220,10000081,48,1246,29,1107,0.130863312,1.470292977,0.90137153,2.436052204,0.256994445,DB0122010000081_,1.358700809,0.385461685,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,rifaximin,DB01220
,25171,DB08934,10000081,45,4444,65,6139,0.846574702,0.956361239,0.637693989,1.423278472,0.922995277,DB0893410000081_,0.080131162,-0.044619573,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,sofosbuvir,DB08934
,25172,DB00811,10003445,23,2775,50,4106,0.149679396,0.68067067,0.395422519,1.139479926,0.283524155,DB0081110003445_,1.260457958,-0.384676687,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,ribavirin,DB00811
,25173,DB01220,10003445,36,1258,44,1092,0.139680792,0.710324529,0.44070602,1.138304027,0.269359864,DB0122010003445_,1.311707009,-0.342033331,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,rifaximin,DB01220
,25174,DB08934,10003445,23,4466,36,6168,0.692791878,0.882409428,0.498431526,1.532723749,0.814936921,DB0893410003445_,0.204644567,-0.125099126,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,sofosbuvir,DB08934
,25175,DB01220,10003549,40,1254,25,1111,0.207599034,1.417340024,0.832931756,2.454556642,0.358390271,DB0122010003549_,1.026132745,0.348781892,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,rifaximin,DB01220
,25195,DB01220,10016256,67,1227,47,1089,0.248961215,1.265079772,0.850155619,1.895505137,0.408388055,DB0122010016256_,0.895537441,0.235135181,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,rifaximin,DB01220
,25203,DB00811,10019641,24,2774,53,4103,0.128161122,0.669814645,0.394434219,1.107242421,0.253068032,DB0081110019641_,1.374096926,-0.400754254,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,ribavirin,DB00811
,25204,DB01220,10019641,48,1246,54,1082,0.223894698,0.771979052,0.507568146,1.171129165,0.37838823,DB0122010019641_,0.971834547,-0.258797864,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,rifaximin,DB01220
,25205,DB08934,10019641,19,4470,50,6154,0.014388747,0.523191232,0.290888287,0.90472683,0.047642277,DB0893410019641_,3.044034742,-0.647808238,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,sofosbuvir,DB08934
,25206,DB00811,10019663,17,2781,35,4121,0.320752365,0.719784582,0.377332558,1.322765624,0.489007361,DB0081110019663_,0.715377737,-0.328803303,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,ribavirin,DB00811
,25207,DB01220,10019663,36,1258,45,1091,0.113532426,0.693910736,0.431441625,1.108996469,0.231430262,DB0122010019663_,1.463476695,-0.365411949,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,rifaximin,DB01220
,25212,DB00811,10023126,31,2767,50,4106,0.819856113,0.920025912,0.566554906,1.472971666,0.90407224,DB0081110023126_,0.100846011,-0.083353444,NA,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,ribavirin,DB00811
,25215,DB01220,10028813,63,1231,55,1081,1,1.005876229,0.682647258,1.485837581,1,DB0122010028813_,0,0.005859031,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,rifaximin,DB01220
,25219,DB00811,10035528,62,2736,85,4071,0.670961678,1.085306131,0.766540102,1.529375524,0.800371966,DB0081110035528_,0.222678702,0.081862095,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,ribavirin,DB00811
,25242,DB00811,10047942,91,2707,76,4080,0.000217882,1.804463751,1.310646134,2.490298063,0.001548681,DB0081110047942_,6.470351914,0.590263457,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,ribavirin,DB00811
,25261,DB00374,10012575,88,17628,19,5705,0.114994728,1.498873234,0.904401721,2.609473926,0.23361219,DB0037410012575_,1.454092847,0.404713649,NA,10012575,Device breakage,10077536,Product issues,Prod,treprostinil,DB00374
,25262,DB06403,10012575,60,21411,13,6648,0.271577664,1.433013923,0.77737967,2.847635787,0.434395357,DB0640310012575_,0.833800199,0.359779865,NA,10012575,Device breakage,10077536,Product issues,Prod,ambrisentan,DB06403
,25263,DB00230,10017577,686,18988,232,8419,0.000404162,1.311084797,1.125468908,1.531533776,0.002585083,DB0023010017577_,5.957997509,0.270854884,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,25265,DB00656,10017577,171,11842,89,6530,0.695655065,1.059484858,0.813766198,1.387262625,0.816830399,DB0065610017577_,0.202323795,0.057782807,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,25266,DB00695,10017577,428,27621,232,20296,0.000188503,1.355575721,1.151449582,1.599105435,0.001371432,DB0069510017577_,6.591899503,0.30422625,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,25267,DB00230,10025082,46,19628,12,8639,0.116764819,1.687162161,0.878985104,3.50072416,0.236253041,DB0023010025082_,1.442851841,0.523047923,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,25268,DB00264,10025082,75,29532,53,24839,0.374498173,1.190213884,0.825846398,1.726015635,0.544376301,DB0026410025082_,0.608114541,0.174133026,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,25272,DB00695,10025082,127,27922,68,20460,0.041704976,1.368518879,1.01095067,1.86637296,0.109135875,DB0069510025082_,2.215161615,0.313729045,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,25273,DB00996,10025082,85,38868,29,22396,0.014632009,1.688867167,1.095971348,2.671759104,0.048338132,DB0099610025082_,3.029534543,0.524057988,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,25274,DB00295,10035664,375,14288,368,9234,2.43401220185666e-08,0.658601425,0.56743271,0.764380577,5.01395068384031e-07,DB0029510035664_,14.50587149,-0.417636745,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,morphine,DB00295
,25285,DB00333,10053762,55,3016,54,3098,0.847074331,1.046219093,0.702944755,1.557713332,0.923260441,DB0033310053762_,0.079843916,0.045182802,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,methadone,DB00333
,25297,DB00924,10022116,74,10088,13,4238,0.002043015,2.391238675,1.3143037,4.705932535,0.009895087,DB0092410022116_,4.615716911,0.871811506,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,25298,DB00333,10024855,27,3044,48,3104,0.020335071,0.573640704,0.343200903,0.940743147,0.062614344,DB0033310024855_,2.770760896,-0.555752029,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,methadone,DB00333
,25300,DB00924,10024855,89,10073,21,4230,0.015588062,1.779659844,1.094874002,3.019866011,0.050806894,DB0092410024855_,2.979723225,0.576422247,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,25301,DB00367,10047700,117,22683,10,457,0.000248837,0.235754997,0.122694447,0.507882996,0.001728283,DB0036710047700_,6.36062689,-1.444962161,male,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,levonorgestrel,DB00367
,25312,DB00338,10028034,41,33633,14,22258,0.037696051,1.938073604,1.034686431,3.850337957,0.101008277,DB0033810028034_,2.292552814,0.661694492,NA,10028034,Mouth ulceration,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,25314,DB00451,10028034,58,47213,9,15410,0.033025245,2.10327703,1.034721167,4.830524757,0.091337182,DB0045110028034_,2.393197325,0.743496619,NA,10028034,Mouth ulceration,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,25317,DB00338,10033553,58,33616,42,22230,0.683033721,0.91321565,0.603179569,1.393042897,0.808418727,DB0033810033553_,0.212675128,-0.090783227,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,25318,DB00381,10033553,62,29298,38,22849,0.267574038,1.272433235,0.835975487,1.959654603,0.429902862,DB0038110033553_,0.844195998,0.240931,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,25319,DB00451,10033553,66,47205,50,15369,1.21581716355853e-05,0.429769107,0.292972799,0.63389746,0.000128888,DB0045110033553_,8.956567544,-0.844507175,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,25321,DB01268,10033553,103,2040,125,3005,0.167964048,1.21373047,0.920043198,1.598272226,0.30810112,DB0126810033553_,1.17732724,0.19369865,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,sunitinib,DB01268
,25324,DB08879,10042945,55,1223,8,105,0.161094623,0.590523834,0.270051466,1.474355698,0.298963686,DB0887910042945_,1.207433165,-0.526745283,NA,10042945,Systemic lupus erythematosus,10028395,Musculoskeletal and connective tissue disorders,Musc,belimumab,DB08879
,25338,DB00030,10013700,36,2170,19,1802,0.133072124,1.57324242,0.875293356,2.914364476,0.260040203,DB0003010013700_,1.346919031,0.453138725,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,insulin human,DB00030
,25339,DB00047,10013700,112,9173,59,8459,0.000502971,1.750485391,1.264115016,2.445428296,0.003105613,DB0004710013700_,5.774544187,0.559893116,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,insulin glargine,DB00047
,25340,DB00656,10013700,359,11654,81,6538,1.77825670016209e-15,2.486339164,1.944702132,3.210969898,1.16127894071455e-13,DB0065610013700_,29.78408428,0.910811413,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,trazodone,DB00656
,25341,DB00736,10013700,400,10191,61,5492,2.20227780382798e-25,3.53359377,2.687603786,4.714903534,3.47668901343053e-23,DB0073610013700_,51.71337673,1.262315418,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,esomeprazole,DB00736
,25342,DB01409,10013700,104,5927,34,3932,0.000215497,2.029099553,1.362586679,3.090064743,0.001534636,DB0140910013700_,6.479461888,0.707592125,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,tiotropium,DB01409
,25347,DB00316,10018985,42,65432,68,36885,4.46366209788351e-08,0.34818012,0.231136326,0.519107106,8.71027158447425e-07,DB0031610018985_,13.95359268,-1.055035348,male,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,25351,DB01076,10018985,36,25711,49,25534,0.159077871,0.729643431,0.460780005,1.14549918,0.29625633,DB0107610018985_,1.216530221,-0.315199314,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,25354,DB14726,10018985,33,1984,40,2808,0.550201051,1.167599272,0.710769904,1.906249167,0.704554338,DB1472610018985_,0.350189821,0.154949736,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,dabigatran,DB14726
,25356,DB01017,10019211,61,1408,31,870,0.44344768,1.215738269,0.769565056,1.955271511,0.611575753,DB0101710019211_,0.491716451,0.195351521,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,minocycline,DB01017
,25360,DB01017,10037660,44,1425,38,863,0.131967066,0.701367241,0.440057663,1.122261903,0.258592093,DB0101710037660_,1.352503387,-0.354723648,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,minocycline,DB01017
,25383,DB00203,10051055,34,13844,48,8890,0.000405311,0.454870886,0.284032178,0.721312028,0.002591486,DB0020310051055_,5.955523914,-0.787741667,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,sildenafil,DB00203
,25386,DB00338,10051055,245,33429,228,22044,0.000226945,0.708615419,0.588722581,0.853110364,0.001602488,DB0033810051055_,6.436197994,-0.344442327,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,omeprazole,DB00338
,25387,DB00381,10051055,161,29199,173,22714,0.003342844,0.723957316,0.580047572,0.903164321,0.014760061,DB0038110051055_,4.215830316,-0.323022844,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,25388,DB00706,10051055,9,1066,137,15788,1,0.972954312,0.434369548,1.908992617,1,DB0070610051055_,0,-0.027418154,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,tamsulosin,DB00706
,25389,DB00722,10051055,151,25252,209,25823,0.004997032,0.738831781,0.59481664,0.915923572,0.020457438,DB0072210051055_,3.88940877,-0.302685015,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,lisinopril,DB00722
,25393,DB14513,10051055,38,7139,42,3522,0.000460164,0.446391068,0.279560855,0.710758607,0.00288123,DB1451310051055_,5.849538096,-0.806559876,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,magnesium,DB14513
,25394,DB00165,10003549,78,2067,37,1329,0.144926771,1.355316995,0.899240627,2.075320568,0.276936511,DB0016510003549_,1.283967001,0.304035372,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pyridoxine,DB00165
,25396,DB00650,10003549,76,2055,71,1943,1,1.012081298,0.718091884,1.427846165,1,DB0065010003549_,0,0.012008902,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,leucovorin,DB00650
,25398,DB01285,10003549,56,1220,15,594,0.039163665,1.817190641,1.003497181,3.489549193,0.103955257,DB0128510003549_,2.263794692,0.597291704,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,corticotropin,DB01285
,25417,DB01137,10000081,120,7652,87,5506,1,0.992483002,0.745154292,1.32641772,1,DB0113710000081_,0,-0.007545393,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,25418,DB01137,10022116,52,7720,23,5570,0.0597038,1.631162731,0.979432076,2.796012374,0.142924806,DB0113710022116_,1.945436616,0.489293093,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,levofloxacin,DB01137
,25419,DB01137,10033371,282,7490,133,5460,3.27824108306361e-05,1.545589215,1.249336968,1.919836854,0.000306704,DB0113710033371_,8.089626539,0.435405207,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,25422,DB01137,10049119,34,7738,22,5571,0.786460377,1.112677179,0.631373752,1.99920732,0.88414144,DB0113710049119_,0.12313823,0.106768984,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,levofloxacin,DB01137
,25425,DB00190,10011906,186,3111,426,4248,7.09697770221214e-09,0.59623261,0.496057879,0.714581632,1.64791571468769e-07,DB0019010011906_,15.61858436,-0.517124403,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,25426,DB00215,10011906,451,10652,370,4906,3.64913450676698e-15,0.561389505,0.486147817,0.648650507,2.27832542779976e-13,DB0021510011906_,29.1101655,-0.577340309,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,25427,DB00281,10011906,337,11121,237,5434,3.19525572366569e-05,0.694791655,0.584766103,0.826586565,0.000300008,DB0028110011906_,8.111700737,-0.364143255,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,25428,DB00476,10011906,391,16866,208,5969,4.85742954518984e-06,0.665290381,0.559341446,0.793099042,5.76422282597359e-05,DB0047610011906_,9.761255129,-0.407531671,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,25429,DB00745,10011906,37,2540,24,1059,0.118497223,0.64284955,0.372346057,1.129216858,0.238939781,DB0074510011906_,1.431543721,-0.441844563,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,modafinil,DB00745
,25431,DB01062,10011906,136,4350,100,1645,1.33158258973094e-06,0.514337973,0.391812506,0.67707066,1.85041757182542e-05,DB0106210011906_,10.89751414,-0.664874695,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,25432,DB01156,10011906,360,13262,306,6022,7.93343283896501e-15,0.534204888,0.455992786,0.626164302,4.7339451117411e-13,DB0115610011906_,28.37884729,-0.626975828,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,25434,DB00115,10038428,75,18350,50,10422,0.401680827,0.851946168,0.587298161,1.245068193,0.571407416,DB0011510038428_,0.55965281,-0.160231938,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,cyanocobalamin,DB00115
,25435,DB00169,10038428,107,38584,86,18089,0.000260139,0.583297837,0.434796228,0.784490846,0.001794921,DB0016910038428_,6.322793996,-0.539057353,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,25437,DB00213,10038428,69,18826,54,13367,0.646874575,0.907262625,0.625772581,1.321309098,0.782237168,DB0021310038428_,0.2455973,-0.097323317,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,25440,DB00316,10038428,155,65319,122,36831,0.006955176,0.716411566,0.561266281,0.916126445,0.026664459,DB0031610038428_,3.624423741,-0.333500464,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,25441,DB00421,10038428,54,8849,34,5218,0.824928049,0.936541549,0.597830276,1.485730617,0.90736217,DB0042110038428_,0.097213603,-0.065561392,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,spironolactone,DB00421
,25443,DB00635,10038428,70,32983,52,23742,0.854884619,0.968981345,0.666934326,1.415741867,0.929630334,DB0063510038428_,0.072968262,-0.031509919,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,25444,DB00695,10038428,149,27900,106,20422,0.848953281,1.028905136,0.796139394,1.333551295,0.924752367,DB0069510038428_,0.078229289,0.028495262,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,25446,DB00761,10038428,49,15258,33,8592,0.422405952,0.8361548,0.526492343,1.343283316,0.591447087,DB0076110038428_,0.525183055,-0.178941515,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,potassium chloride,DB00761
,25450,DB00996,10038428,105,38848,85,22340,0.023323103,0.710398878,0.528348082,0.957466942,0.069636386,DB0099610038428_,2.664468056,-0.341928666,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,25453,DB01076,10038428,103,25644,107,25476,0.78222341,0.956297692,0.722051987,1.266097559,0.881447445,DB0107610038428_,0.126189899,-0.044686022,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,25455,DB06643,10038428,45,52376,13,7502,0.04360818,0.495805213,0.262690443,1.002323331,0.112830103,DB0664310038428_,2.181872107,-0.701572145,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,denosumab,DB06643
,25457,DB00316,10003658,476,64998,431,36522,1.43586126641954e-12,0.620534567,0.543236136,0.70904608,6.29026889797295e-11,DB0031610003658_,23.4894322,-0.477173967,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,25458,DB00482,10003658,50,8209,21,3050,0.687806405,0.884648024,0.520724111,1.553322527,0.811790995,DB0048210003658_,0.208512367,-0.122565426,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,celecoxib,DB00482
,25459,DB01373,10003658,227,22493,98,7283,0.019563497,0.750010323,0.588343737,0.961956048,0.060750961,DB0137310003658_,2.800972377,-0.287668309,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,calcium,DB01373
,25462,DB06724,10003658,108,7821,76,3843,0.021723603,0.698263663,0.51450524,0.951704173,0.065999758,DB0672410003658_,2.71810421,-0.359158507,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,calcium carbonate,DB06724
,25463,DB11089,10003658,150,10025,144,8263,0.194531354,0.858591538,0.677200407,1.08890386,0.342424687,DB1108910003658_,1.071703537,-0.152461979,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,docusate,DB11089
,25465,DB11133,10003658,22,2409,32,1542,0.003063091,0.440157517,0.242677308,0.784729709,0.013759438,DB1113310003658_,4.286030255,-0.820622624,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,omega-3 fatty acids,DB11133
,25469,DB00316,10020524,36,65438,26,36927,0.355558934,0.781363767,0.45877908,1.347899214,0.525311602,DB0031610020524_,0.643763664,-0.246714466,NA,10020524,Hydronephrosis,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,25501,DB00264,10040047,358,29249,368,24524,0.00689206,0.815677923,0.702526313,0.946974598,0.026475383,DB0026410040047_,3.631539926,-0.203735705,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,metoprolol,DB00264
,25502,DB00338,10040047,350,33324,319,21953,3.48538493875583e-05,0.722812336,0.618672967,0.844706372,0.000323608,DB0033810040047_,8.035978543,-0.324605654,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,omeprazole,DB00338
,25503,DB00482,10040047,46,8213,11,3060,0.231556377,1.558079282,0.793661797,3.340289512,0.387816065,DB0048210040047_,0.947224111,0.443453833,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,celecoxib,DB00482
,25504,DB00722,10040047,220,25183,263,25769,0.090889611,0.855970371,0.711726288,1.028670243,0.19664445,DB0072210040047_,1.626358002,-0.155519517,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,lisinopril,DB00722
,25506,DB06643,10040047,82,52339,31,7484,2.0930165727273e-05,0.378242539,0.247228411,0.592202512,0.000207682,DB0664310040047_,8.479502879,-0.972219651,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,denosumab,DB06643
,25510,DB14726,10040047,19,1998,31,2817,0.66709201,0.864186154,0.459842926,1.58393164,0.797694128,DB1472610040047_,0.226030053,-0.145967078,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,dabigatran,DB14726
,25514,DB00264,10047289,23,29584,37,24855,0.013725797,0.522268039,0.296197905,0.9027719,0.045819479,DB0026410047289_,3.08304598,-0.649574338,NA,10047289,Ventricular extrasystoles,10007541,Cardiac disorders,Card,metoprolol,DB00264
,25529,DB00169,10058080,109,38582,66,18109,0.104834087,0.77519466,0.565546001,1.069506119,0.218236564,DB0016910058080_,1.522175647,-0.254641107,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,25530,DB00193,10058080,71,19249,29,8673,0.745510672,1.103110531,0.706313788,1.764085517,0.854763634,DB0019310058080_,0.1569303,0.098133944,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,tramadol,DB00193
,25531,DB00264,10058080,67,29540,64,24828,0.483133833,0.879888459,0.614986672,1.25986857,0.6473225,DB0026410058080_,0.434910655,-0.127960131,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,25532,DB00316,10058080,184,65290,123,36830,0.153172976,0.843864117,0.667761698,1.069473911,0.288426941,DB0031610058080_,1.243313464,-0.169763797,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,25533,DB00338,10058080,98,33576,74,22198,0.391789001,0.875551382,0.640478566,1.201189099,0.561667515,DB0033810058080_,0.576845215,-0.132901441,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,25534,DB00451,10058080,126,47145,45,15374,0.594225665,0.913072099,0.644564113,1.314256975,0.740162623,DB0045110058080_,0.300885356,-0.090940433,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,25536,DB00722,10058080,48,25355,77,25955,0.015378752,0.638136985,0.435289972,0.927304947,0.050280551,DB0072210058080_,2.990136928,-0.449202308,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,lisinopril,DB00722
,25537,DB01373,10058080,53,22667,21,7360,0.41974877,0.819473422,0.485614095,1.431364655,0.588667275,DB0137310058080_,0.529894153,-0.199093313,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,calcium,DB01373
,25542,DB11089,10058080,34,10141,34,8373,0.464924066,0.825669519,0.497470586,1.370376075,0.631782164,DB1108910058080_,0.459210621,-0.191560683,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,docusate,DB11089
,25546,DB00820,10018884,212,11703,49,5767,5.08541554314958e-07,2.131946951,1.553450002,2.976222546,7.87387560565924e-06,DB0082010018884_,11.75196016,0.757035624,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,tadalafil,DB00820
,25548,DB00820,10047942,17,11898,34,5782,1.24921798587679e-06,0.243004638,0.127190678,0.447663139,1.74482070714753e-05,DB0082010047942_,10.95627366,-1.414674751,male,10047942,White blood cell count decreased,10022891,Investigations,Inv,tadalafil,DB00820
,25549,DB00820,10049414,95,11820,38,5778,0.309663203,1.222041068,0.829438832,1.83288052,0.477110041,DB0082010049414_,0.740008121,0.200522467,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,25554,DB00030,10003988,44,2162,21,1800,0.043662366,1.744181647,1.010828169,3.100502617,0.112914727,DB0003010003988_,2.181122376,0.556285475,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin human,DB00030
,25555,DB00046,10003988,90,5369,54,4638,0.035460686,1.439692433,1.013707492,2.061520848,0.096405121,DB0004610003988_,2.339195958,0.364429502,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin lispro,DB00046
,25556,DB01307,10003988,43,2481,24,2045,0.138507013,1.47668204,0.87284585,2.553293962,0.267685515,DB0130710003988_,1.317942441,0.389797706,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin detemir,DB01307
,25561,DB00046,10013968,231,5228,158,4534,0.02568157,1.267914986,1.02697067,1.568570102,0.074996119,DB0004610013968_,2.590318907,0.237373808,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin lispro,DB00046
,25562,DB00316,10008629,123,65351,66,36887,0.762313907,1.051922004,0.773570916,1.441425029,0.868285351,DB0031610008629_,0.141234873,0.050618971,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,25563,DB00904,10008629,67,23002,34,14422,0.357142286,1.235500686,0.805612817,1.9266623,0.526868808,DB0090410008629_,0.640803702,0.211476302,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,ondansetron,DB00904
,25565,DB00904,10037377,260,22809,156,14300,0.685518926,1.044911913,0.852516417,1.284086541,0.810109699,DB0090410037377_,0.21058561,0.043932588,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,25569,DB00559,10008469,134,9525,25,3281,0.004334888,1.846325364,1.195534351,2.959952217,0.018230735,DB0055910008469_,4.004646381,0.613197374,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,25570,DB00682,10008469,263,19196,89,16275,2.65369500075699e-15,2.505246284,1.961004556,3.226049182,1.69548474578239e-13,DB0068210008469_,29.40563752,0.918387047,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,25572,DB01118,10008479,48,3015,78,4631,0.783570424,0.945222923,0.6436517,1.375915986,0.882171087,DB0111810008479_,0.125369266,-0.056334482,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,25573,DB01118,10019211,75,2988,55,4654,2.60738524289145e-05,2.123767356,1.474886774,3.074184328,0.000250445,DB0111810019211_,8.292271564,0.753191566,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,amiodarone,DB01118
,25575,DB00682,10029216,55,19404,25,16339,0.009625537,1.852440091,1.13448588,3.103653545,0.034527877,DB0068210029216_,3.365988254,0.616503738,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,25577,DB01118,10030095,40,3023,28,4681,0.0016207,2.211879951,1.327813173,3.731168782,0.008182883,DB0111810030095_,4.805710687,0.79384281,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,25587,DB13961,10003549,290,9167,256,6158,0.001878899,0.760999629,0.638966467,0.906744212,0.009248634,DB1396110003549_,4.683279439,-0.273122408,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,25589,DB06605,10013573,551,13522,393,12640,5.90442448648816e-05,1.310568651,1.146738972,1.498904316,0.000509179,DB0660510013573_,7.582710686,0.270461128,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,25591,DB00285,10019211,525,10426,100,3618,1.1161727798547e-08,1.821803246,1.463180132,2.287040822,2.48647377268209e-07,DB0028510019211_,15.2072301,0.599826805,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,25592,DB06605,10019211,675,13398,307,12726,1.6253289811553e-27,2.08835286,1.817965936,2.403037782,3.05155516211907e-25,DB0660510019211_,56.44897597,0.73637565,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,25593,DB14509,10019211,42,843,10,541,0.003428631,2.693767645,1.316051738,6.074269422,0.015073322,DB1450910019211_,4.194828847,0.990940825,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lithium carbonate,DB14509
,25601,DB06605,10014498,32,14041,41,12992,0.196768527,0.722190445,0.43992174,1.176051574,0.345091624,DB0660510014498_,1.063945319,-0.3254664,NA,10014498,Embolic stroke,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,25602,DB00381,10066901,39,29321,48,22839,0.039373747,0.632896285,0.403727552,0.986597856,0.104396926,DB0038110066901_,2.259555045,-0.457448717,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,25603,DB00635,10066901,255,32798,124,23670,0.000301631,1.484109676,1.19208734,1.855778804,0.002026942,DB0063510066901_,6.201227179,0.394815048,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,25608,DB06605,10066901,22,14051,37,12996,0.026512207,0.549966959,0.30884444,0.957674685,0.076887887,DB0660510066901_,2.565406929,-0.597897077,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,25610,DB08908,10044565,99,10574,35,3244,0.474051835,0.867810484,0.583482711,1.317817854,0.63978996,DB0890810044565_,0.446615344,-0.141781925,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,25611,DB08908,10049848,188,10485,66,3213,0.369978896,0.872912723,0.654108696,1.17709468,0.539612433,DB0890810049848_,0.616904113,-0.135919702,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,25613,DB08908,10061428,95,10578,34,3245,0.465059379,0.85718616,0.572534828,1.311014505,0.631931647,DB0890810061428_,0.458974045,-0.154100161,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,dimethyl fumarate,DB08908
,25614,DB05259,10003239,126,11144,27,2701,0.609161047,1.131061926,0.739985436,1.787447852,0.751674676,DB0525910003239_,0.28545166,0.123156949,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,glatiramer,DB05259
,25615,DB08908,10003239,97,10576,23,3256,0.281338588,1.298362527,0.815799227,2.147939458,0.445306645,DB0890810003239_,0.808992145,0.261103876,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,dimethyl fumarate,DB08908
,25616,DB01050,10013709,1012,17096,421,8950,9.81743644243776e-05,1.258444014,1.118763912,1.417346332,0.000784351,DB0105010013709_,7.150654562,0.229876049,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,25617,DB05259,10013709,458,10812,122,2606,0.335401345,0.904835232,0.735909496,1.119315522,0.504623471,DB0525910013709_,0.683942731,-0.100002416,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,25618,DB05259,10033425,203,11067,43,2685,0.465159542,1.14534846,0.818326439,1.63555574,0.631986074,DB0525910033425_,0.458887921,0.135708923,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,glatiramer,DB05259
,25619,DB08908,10033425,150,10523,39,3240,0.388036792,1.18420222,0.825721737,1.73450875,0.558047899,DB0890810033425_,0.583310479,0.169069316,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,dimethyl fumarate,DB08908
,25641,DB00497,10000891,22,19245,33,16342,0.041886818,0.566119748,0.314291683,1.001059576,0.109491823,DB0049710000891_,2.211905412,-0.568949654,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,oxycodone,DB00497
,25643,DB00635,10000891,46,33007,62,23732,0.00121377,0.533468853,0.356021677,0.79421385,0.006459666,DB0063510000891_,5.042177622,-0.628354592,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,prednisone,DB00635
,25644,DB00758,10000891,93,8207,131,9943,0.280321849,0.860098852,0.651058934,1.132452323,0.444184061,DB0075810000891_,0.811516252,-0.150707953,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,25645,DB00996,10000891,39,38914,56,22369,9.52032396841747e-06,0.400333109,0.258865171,0.613543799,0.000104224,DB0099610000891_,9.168968562,-0.915458306,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,gabapentin,DB00996
,25648,DB00158,10007559,97,16718,85,8019,6.56420609428785e-05,0.547366523,0.40432,0.742242303,0.000555595,DB0015810007559_,7.495470193,-0.602636641,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,folic acid,DB00158
,25649,DB00295,10007559,52,14611,50,9552,0.054056437,0.679933121,0.451792565,1.024135888,0.132587453,DB0029510007559_,2.020512831,-0.385760837,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,morphine,DB00295
,25651,DB00332,10007559,50,2634,41,1615,0.190600851,0.747794407,0.482435143,1.164762519,0.337324493,DB0033210007559_,1.086709923,-0.290627196,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,ipratropium,DB00332
,25653,DB00497,10007559,77,19190,92,16283,0.030054019,0.710183007,0.51736695,0.972620724,0.084825562,DB0049710007559_,2.46715834,-0.342232586,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,oxycodone,DB00497
,25654,DB00563,10007559,113,46533,42,15306,0.514272651,0.884959586,0.615613037,1.293748333,0.674247781,DB0056310007559_,0.394157608,-0.122213301,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,methotrexate,DB00563
,25655,DB00758,10007559,136,8164,174,9900,0.687119103,0.947802387,0.750223336,1.195445259,0.811307667,DB0075810007559_,0.209107929,-0.053609251,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,25657,DB08877,10007559,20,3269,34,3195,0.055315551,0.57497134,0.312880429,1.030394014,0.134882812,DB0887710007559_,2.00334894,-0.553435083,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,ruxolitinib,DB08877
,25666,DB00635,10007625,23,33030,38,23756,0.001626226,0.435323424,0.247527729,0.749893306,0.008205269,DB0063510007625_,4.802978772,-0.831666022,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,prednisone,DB00635
,25671,DB00153,10008531,86,7337,26,3413,0.052953492,1.538604689,0.980232527,2.491176517,0.130569009,DB0015310008531_,2.035853386,0.430875959,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,25672,DB00158,10008531,143,16672,58,8046,0.29010525,1.189847082,0.870035341,1.645577466,0.455303111,DB0015810008531_,0.786791904,0.173824796,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,25676,DB00758,10008531,51,8249,54,10020,0.492702434,1.147199358,0.76588673,1.716192442,0.655556268,DB0075810008531_,0.422271139,0.137323631,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,25684,DB00497,10011078,20,19247,32,16343,0.025944237,0.530715294,0.287538694,0.957237501,0.075570066,DB0049710011078_,2.58269503,-0.63352957,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,oxycodone,DB00497
,25686,DB00758,10011078,66,8234,118,9956,0.011271886,0.676310154,0.491856857,0.923145065,0.039157012,DB0075810011078_,3.240175764,-0.391103501,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,25687,DB00996,10011078,45,38908,65,22360,2.12061580801558e-06,0.397865658,0.265751531,0.591069676,2.79120613488681e-05,DB0099610011078_,10.48645166,-0.921640874,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,gabapentin,DB00996
,25691,DB00158,10016288,45,16770,43,8061,0.001885607,0.503035417,0.323457096,0.78329127,0.0092751,DB0015810016288_,4.680421888,-0.687094699,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,folic acid,DB00158
,25695,DB00635,10016288,219,32834,337,23457,4.84257842654738e-19,0.464263071,0.389516286,0.552486057,4.58692518709182e-17,DB0063510016288_,37.62073668,-0.767303925,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,25697,DB00996,10016288,90,38863,118,22307,3.29725358271599e-09,0.437790789,0.328829183,0.581219324,8.2541248020657e-08,DB0099610016288_,16.30996769,-0.826014134,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,gabapentin,DB00996
,25699,DB08877,10016288,77,3212,185,3044,2.04115550412407e-12,0.39449897,0.296958277,0.519918807,8.7167786232171e-11,DB0887710016288_,23.16318628,-0.93013875,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,ruxolitinib,DB08877
,25700,DB00153,10046571,166,7257,43,3396,0.000393154,1.806463323,1.28137521,2.595374662,0.002526353,DB0015310046571_,5.98097833,0.591370969,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ergocalciferol,DB00153
,25702,DB00332,10046571,73,2611,31,1625,0.082518183,1.46545045,0.945605423,2.319533323,0.182575972,DB0033210046571_,1.70058891,0.38216267,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ipratropium,DB00332
,25704,DB00758,10046571,187,8113,96,9978,1.40239823270279e-12,2.395599427,1.859727103,3.102491771,6.16422032551718e-11,DB0075810046571_,23.50967436,0.873633482,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,clopidogrel,DB00758
,25705,DB01190,10046571,79,4855,25,2260,0.110649598,1.470905471,0.924874865,2.414702901,0.227052163,DB0119010046571_,1.482575493,0.385878178,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,clindamycin,DB01190
,25706,DB08877,10046571,50,3239,15,3214,1.50608004139992e-05,3.307362212,1.822633631,6.35443166,0.000155488,DB0887710046571_,8.768940255,1.196150957,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ruxolitinib,DB08877
,25721,DB00829,10002855,228,7824,83,4371,0.000767017,1.534598153,1.185109592,2.003189893,0.004416441,DB0082910002855_,5.422421176,0.428268557,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,25722,DB00829,10008479,103,7949,38,4416,0.033501144,1.50576361,1.026654473,2.250231478,0.092355263,DB0082910008479_,2.382112579,0.409300152,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,25723,DB00051,10012374,53,25678,20,11400,0.612243778,1.176478384,0.691274064,2.078709887,0.754133308,DB0005110012374_,0.282186126,0.162525555,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,adalimumab,DB00051
,25724,DB00476,10012374,123,17134,25,6152,0.008507493,1.766572668,1.140794656,2.838175529,0.031286386,DB0047610012374_,3.464572221,0.569041324,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,25726,DB00476,10013709,979,16278,310,5867,0.055003334,1.138235575,0.997114962,1.302065256,0.134339586,DB0047610013709_,2.007384462,0.129479322,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,25735,DB06724,10001760,102,7827,6,3913,7.09464906558088e-12,8.498296222,3.767642183,23.71772867,2.78125056955695e-10,DB0672410001760_,22.00295026,2.139865699,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,calcium carbonate,DB06724
,25737,DB00484,10016256,115,2392,96,1684,0.251642239,0.843387259,0.632788927,1.126035485,0.411638688,DB0048410016256_,0.887609285,-0.170329045,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,brimonidine,DB00484
,25740,DB06724,10016256,643,7286,254,3665,0.001498476,1.273326903,1.093370181,1.486348123,0.007685355,DB0672410016256_,4.868438682,0.241633084,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,25741,DB00484,10025482,55,2452,19,1761,0.005854014,2.078628847,1.209413868,3.722640704,0.023215562,DB0048410025482_,3.762932435,0.731708468,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,brimonidine,DB00484
,25743,DB06724,10025482,254,7675,75,3844,3.91248730252174e-05,1.696132369,1.3020309,2.231530878,0.000358139,DB0672410025482_,7.934588262,0.528350582,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,25753,DB06637,10037844,79,6083,24,1995,0.818539813,1.079535121,0.67408578,1.788239698,0.903211688,DB0663710037844_,0.101798326,0.076530505,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dalfampridine,DB06637
,25755,DB01164,10054236,24,6500,32,7904,0.788746101,0.911977284,0.513440973,1.599601749,0.885555871,DB0116410054236_,0.121539728,-0.092140197,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,calcium chloride,DB01164
,25759,DB00028,10038695,31,13427,37,5578,2.21710993972236e-05,0.348086215,0.208600036,0.57721928,0.0002181,DB0002810038695_,8.430556655,-1.055305086,male,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human immunoglobulin g,DB00028
,25760,DB00073,10038695,77,7329,111,6296,0.000513447,0.595949199,0.438815083,0.805851333,0.003154737,DB0007310038695_,5.758850047,-0.517599851,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rituximab,DB00073
,25768,DB01268,10019030,41,2102,59,3071,1,1.015265167,0.661750887,1.544568388,1,DB0126810019030_,0,0.015149827,NA,10019030,Hair colour changes,10040785,Skin and subcutaneous tissue disorders,Skin,sunitinib,DB01268
,25769,DB00715,10028813,289,4554,91,2196,0.000447104,1.53133997,1.19881103,1.971102589,0.002813872,DB0071510028813_,5.873193801,0.426143149,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,paroxetine,DB00715
,25770,DB00715,10033775,51,4792,18,2269,0.303220123,1.341564492,0.768470927,2.445810767,0.46968831,DB0071510033775_,0.755685975,0.293836464,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,paroxetine,DB00715
,25771,DB01268,10033775,27,2116,41,3089,0.901837649,0.961354649,0.566780503,1.606474121,0.957112391,DB0126810033775_,0.043834453,-0.039411897,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,sunitinib,DB01268
,25772,DB00715,10047700,148,4695,41,2246,0.001555399,1.726720402,1.209539305,2.513396339,0.007920794,DB0071510047700_,4.838263782,0.546223888,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,paroxetine,DB00715
,25777,DB00091,10013968,174,5336,69,2601,0.164881268,1.229142622,0.92099272,1.655707845,0.303969155,DB0009110013968_,1.190829046,0.206316871,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclosporine,DB00091
,25778,DB00394,10013968,123,1516,52,742,0.451382431,1.157683332,0.819957633,1.65334306,0.619043472,DB0039410013968_,0.479579779,0.14642088,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,beclomethasone dipropionate,DB00394
,25779,DB01591,10013968,62,1893,16,640,0.426199331,1.309943463,0.740224438,2.450256045,0.594839515,DB0159110013968_,0.519463632,0.269983978,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,solifenacin,DB01591
,25782,DB00381,10022595,49,29311,74,22813,0.000347734,0.515381357,0.351536827,0.749760659,0.002281912,DB0038110022595_,6.082741471,-0.662848153,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,amlodipine,DB00381
,25786,DB00641,10022595,41,14083,52,12423,0.09542973,0.695538541,0.449983922,1.068693961,0.203914973,DB0064110022595_,1.590052169,-0.363068854,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,simvastatin,DB00641
,25787,DB00678,10022595,34,15565,24,10700,1,0.973862228,0.560396718,1.717499183,1,DB0067810022595_,0,-0.026485435,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,losartan,DB00678
,25789,DB00695,10022595,133,27916,138,20390,0.00448066,0.703957813,0.550138808,0.900457427,0.018712131,DB0069510022595_,3.978583236,-0.351036849,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,furosemide,DB00695
,25790,DB00761,10022595,50,15257,49,8576,0.006246564,0.573618526,0.378611571,0.869377391,0.024445908,DB0076110022595_,3.711292444,-0.555790693,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,potassium chloride,DB00761
,25792,DB00381,10017577,455,28905,203,22684,8.10312083764953e-12,1.758954198,1.486082974,2.08759907,3.1391382640769e-10,DB0038110017577_,21.88190261,0.564719427,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,25793,DB00381,10028334,486,28874,249,22638,3.43201409245993e-08,1.530254881,1.309450476,1.791857759,6.85229703154647e-07,DB0038110028334_,14.19351172,0.42543431,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,25797,DB00005,10000060,228,127854,66,42353,0.379972885,1.144352123,0.866391501,1.529205007,0.55011359,DB0000510000060_,0.597630495,0.134838645,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,25801,DB00502,10014387,49,1345,40,1832,0.021994458,1.66824699,1.069344757,2.616360188,0.066619537,DB0050210014387_,2.7087574,0.511773368,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,haloperidol,DB00502
,25802,DB00502,10053762,60,1334,63,1809,0.164764709,1.291382354,0.884820725,1.883192411,0.303816793,DB0050210053762_,1.191330415,0.255713237,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,haloperidol,DB00502
,25807,DB06228,10011372,29,15883,33,16043,0.703493047,0.887644227,0.519670227,1.508610112,0.822183354,DB0622810011372_,0.19579185,-0.119184262,NA,10011372,Creatinine renal clearance decreased,10022891,Investigations,Inv,rivaroxaban,DB06228
,25811,DB00341,10002198,135,11270,30,5038,0.000337181,2.011550309,1.344158587,3.100580057,0.002222927,DB0034110002198_,6.10893067,0.698905723,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,cetirizine,DB00341
,25812,DB00381,10002198,60,29300,45,22842,0.921642423,1.039458842,0.694220349,1.566269266,0.965386517,DB0038110002198_,0.035226722,0.038700234,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,amlodipine,DB00381
,25815,DB00678,10002198,40,15559,29,10695,0.902473595,0.948134538,0.572898054,1.586805432,0.957195726,DB0067810002198_,0.043747388,-0.053258869,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,losartan,DB00678
,25818,DB00924,10002198,47,10115,10,4241,0.057320953,1.97052882,0.981515317,4.377944387,0.138411763,DB0092410002198_,1.977522247,0.678301943,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,cyclobenzaprine,DB00924
,25819,DB01015,10002198,49,9838,28,9353,0.0390784,1.663676338,1.02417598,2.751626638,0.10380123,DB0101510002198_,2.265277462,0.509029815,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,sulfamethoxazole,DB01015
,25822,DB00175,10013700,378,7753,117,5989,1.08293105224018e-19,2.495484537,2.017062735,3.106347095,1.09270029589763e-17,DB0017510013700_,39.05529461,0.914482914,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,pravastatin,DB00175
,25823,DB00227,10013700,150,2317,50,1753,2.31686682878716e-07,2.269304282,1.626802281,3.211170854,3.87767237151674e-06,DB0022710013700_,12.46027549,0.819473301,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,lovastatin,DB00227
,25824,DB00465,10013700,363,1741,70,813,5.63086162282499e-12,2.420957949,1.842788421,3.216448067,2.24934950996892e-10,DB0046510013700_,22.21520986,0.884163308,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ketorolac,DB00465
,25825,DB00758,10013700,178,8122,94,9980,1.82882887585641e-11,2.326711138,1.798894767,3.025476305,6.68578122418439e-10,DB0075810013700_,21.12586786,0.844455742,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,clopidogrel,DB00758
,25827,DB13867,10013700,65,4485,19,2535,0.011410781,1.933476361,1.141898125,3.422811074,0.039566304,DB1386710013700_,3.229777422,0.659319606,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,fluticasone,DB13867
,25828,DB00175,10019063,34,8097,52,6054,0.001383788,0.488889341,0.307261091,0.76884623,0.007195424,DB0017510019063_,4.934310075,-0.715619112,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,pravastatin,DB00175
,25831,DB00341,10019063,53,11352,30,5038,0.28520706,0.78402645,0.491269823,1.27269916,0.449777565,DB0034110019063_,0.799002118,-0.243312522,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,cetirizine,DB00341
,25832,DB00381,10019063,101,29259,123,22764,0.000911677,0.638875332,0.485788919,0.838532761,0.005107839,DB0038110019063_,5.276978842,-0.448045942,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,25833,DB00451,10019063,205,47066,113,15306,1.4579965702649e-05,0.589976135,0.466305125,0.749583397,0.000151251,DB0045110019063_,8.796568184,-0.527673192,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,25836,DB00678,10019063,73,15526,71,10653,0.040992768,0.705490606,0.501327657,0.993183716,0.107652602,DB0067810019063_,2.228845884,-0.348861823,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,losartan,DB00678
,25837,DB00758,10019063,45,8255,59,10015,0.767107605,0.925307465,0.612792409,1.388932454,0.871974951,DB0075810019063_,0.136994582,-0.077629202,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,clopidogrel,DB00758
,25838,DB00863,10019063,63,10610,42,5798,0.356717731,0.819720478,0.545279701,1.243409066,0.526375431,DB0086310019063_,0.641740574,-0.198791878,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,ranitidine,DB00863
,25840,DB00924,10019063,48,10114,27,4224,0.252602889,0.742475257,0.453381222,1.23935148,0.412824755,DB0092410019063_,0.884732098,-0.297765733,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,25841,DB00999,10019063,81,21349,65,12174,0.046979562,0.710636084,0.505985416,1.001361109,0.119407997,DB0099910019063_,2.125209106,-0.341594817,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,25842,DB01015,10019063,36,9851,35,9346,1,0.975839244,0.594972002,1.601976367,1,DB0101510019063_,0,-0.024457415,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,sulfamethoxazole,DB01015
,25852,DB00537,10048294,33,7524,30,4268,0.066023538,0.623972584,0.368401356,1.060834445,0.154191799,DB0053710048294_,1.869558005,-0.471648848,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,ciprofloxacin,DB00537
,25853,DB00916,10048294,35,5288,34,2397,0.002412439,0.466663253,0.281891704,0.773251246,0.01133553,DB0091610048294_,4.479813276,-0.762147367,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,metronidazole,DB00916
,25864,DB00005,10028300,41,128041,25,42394,0.021597076,0.543018026,0.322382668,0.931850883,0.065711209,DB0000510028300_,2.722485756,-0.610612763,NA,10028300,Muscle disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,25865,DB00005,10042858,76,128006,19,42400,0.341749537,1.324921227,0.793113934,2.320611823,0.510986419,DB0000510042858_,0.671412266,0.281353007,NA,10042858,Synovial cyst,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,25866,DB00005,10043255,113,127969,23,42396,0.036547605,1.627626034,1.032629782,2.671702262,0.098655075,DB0000510043255_,2.316125605,0.487122533,NA,10043255,Tendonitis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,25872,DB00060,10049848,214,9294,56,2409,0.939372389,0.990512853,0.732176577,1.359023216,0.978924127,DB0006010049848_,0.02130114,-0.009532437,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,25875,DB00060,10050296,55,9453,14,2451,1,1.018612373,0.557706487,1.986983,1,DB0006010050296_,0,0.018441283,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,25879,DB00099,10018884,33,2352,40,1915,0.097462954,0.671785997,0.408781823,1.097199447,0.20706545,DB0009910018884_,1.57472035,-0.397815445,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,filgrastim,DB00099
,25880,DB01041,10018884,48,2997,50,3068,1,0.98274336,0.645171613,1.495594577,1,DB0104110018884_,0,-0.017407271,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,thalidomide,DB01041
,25881,DB00904,10029354,337,22732,268,14188,0.003636638,0.784852151,0.665577492,0.926157856,0.015799839,DB0090410029354_,4.147755558,-0.242259922,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,ondansetron,DB00904
,25882,DB00099,10035528,53,2332,59,1896,0.102785367,0.73041455,0.491770943,1.082552935,0.215206335,DB0009910035528_,1.536158015,-0.31414303,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,filgrastim,DB00099
,25884,DB00904,10035669,48,23021,52,14404,0.007187536,0.577590185,0.381654117,0.872467193,0.027346657,DB0090410035669_,3.599161,-0.548890684,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,ondansetron,DB00904
,25885,DB00099,10047942,110,2275,91,1864,0.942308225,0.990412813,0.738116313,1.33156084,0.981419383,DB0009910047942_,0.018755405,-0.00963344,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,filgrastim,DB00099
,25886,DB01041,10047942,37,3008,30,3088,0.390127084,1.266083003,0.758910206,2.127955669,0.560025018,DB0104110047942_,0.579773821,0.235927885,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,thalidomide,DB01041
,25896,DB00571,10010264,104,5019,39,2570,0.108093971,1.36542567,0.933395624,2.033439287,0.223187045,DB0057110010264_,1.499745091,0.311466226,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,25899,DB00571,10020751,44,5079,10,2599,0.019938509,2.251343798,1.114011505,5.025887978,0.061613416,DB0057110020751_,2.786875647,0.811527282,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,propranolol,DB00571
,25905,DB00363,10061284,48,4580,45,6843,0.025844194,1.59359974,1.036896227,2.453390579,0.075345458,DB0036310061284_,2.585671639,0.465995445,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,25908,DB01234,10031264,37,31588,42,32846,0.736268517,0.916059,0.572400854,1.460436082,0.847729553,DB0123410031264_,0.165193618,-0.087674506,NA,10031264,Osteonecrosis,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,25914,DB01234,10007515,139,31486,179,32709,0.063380081,0.806703072,0.641289627,1.013037811,0.149620138,DB0123410007515_,1.899655613,-0.214799619,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,25915,DB01234,10028596,97,31528,215,32673,1.37190830277937e-10,0.467554947,0.363821298,0.597231036,4.37363368569505e-09,DB0123410028596_,19.24767167,-0.760238404,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,25917,DB01234,10065154,59,31566,60,32828,0.927059189,1.022650562,0.701409109,1.490488981,0.969204948,DB0123410065154_,0.031279185,0.022397847,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,dexamethasone,DB01234
,25919,DB00404,10005557,98,19794,42,9820,0.471997905,1.157572942,0.797972305,1.70518503,0.638094169,DB0040410005557_,0.449269406,0.146325522,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,alprazolam,DB00404
,25921,DB00472,10005557,53,10706,19,4293,0.7938872,1.118540734,0.650498244,2.003197226,0.888291402,DB0047210005557_,0.118455435,0.11202492,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,fluoxetine,DB00472
,25922,DB01224,10005557,32,8076,19,5898,0.570383009,1.229980868,0.675532531,2.299218514,0.72095008,DB0122410005557_,0.327185382,0.206998615,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,quetiapine,DB01224
,25924,DB00423,10047895,55,2412,19,1021,0.520751667,1.225255951,0.711611584,2.197937568,0.679809166,DB0042310047895_,0.385943158,0.203149761,NA,10047895,Weight decreased,10022891,Investigations,Inv,methocarbamol,DB00423
,25925,DB00472,10047895,147,10612,53,4259,0.529692849,1.113135228,0.806179192,1.557275955,0.68694378,DB0047210047895_,0.375502825,0.107180563,NA,10047895,Weight decreased,10022891,Investigations,Inv,fluoxetine,DB00472
,25926,DB00588,10047895,353,16171,173,8295,0.641821309,1.046666496,0.868404959,1.265300513,0.778414931,DB0058810047895_,0.250495567,0.045610348,NA,10047895,Weight decreased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,25928,DB00404,10047899,358,19534,82,9780,1.08524364404522e-11,2.185781706,1.712793801,2.817288433,4.12220074909374e-10,DB0040410047899_,21.60946375,0.781973525,NA,10047899,Weight increased,10022891,Investigations,Inv,alprazolam,DB00404
,25929,DB00423,10047899,45,2422,13,1027,0.248727289,1.467680824,0.7740123,2.97869373,0.408127647,DB0042310047899_,0.896175292,0.383683484,NA,10047899,Weight increased,10022891,Investigations,Inv,methocarbamol,DB00423
,25930,DB00588,10047899,274,16250,111,8357,0.034415342,1.269508331,1.012913165,1.599921618,0.09423483,DB0058810047899_,2.361965416,0.238629684,NA,10047899,Weight increased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,25932,DB01224,10028334,68,8040,33,5884,0.054854149,1.507991353,0.979572737,2.363233953,0.13407405,DB0122410028334_,2.009363018,0.410778535,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,quetiapine,DB01224
,25940,DB00005,10054786,107,127975,25,42394,0.130507294,1.417798224,0.910413806,2.28836067,0.256486913,DB0000510054786_,1.360677637,0.349105121,NA,10054786,Skin burning sensation,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,25943,DB00989,10027175,33,801,19,859,0.034457988,1.861924931,1.018654847,3.495767509,0.094331949,DB0098910027175_,2.360935345,0.621610862,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,rivastigmine,DB00989
,25950,DB00390,10011224,124,4021,65,3236,0.005939591,1.535173982,1.123843697,2.113617865,0.023480545,DB0039010011224_,3.751583092,0.428643718,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,25951,DB00635,10011224,839,32214,471,23323,1.10318072644784e-05,1.289670023,1.149168966,1.44872794,0.000118139,DB0063510011224_,9.043652528,0.254386389,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,25952,DB11089,10011224,203,9972,134,8273,0.046643627,1.256800283,1.003445064,1.578275728,0.118783872,DB1108910011224_,2.13044964,0.228569033,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,25953,DB00635,10013573,857,32196,450,23344,3.01379546191797e-08,1.38082557,1.22888594,1.553130142,6.0843021287645e-07,DB0063510013573_,14.31238362,0.322681559,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,25954,DB11089,10013573,291,9884,227,8180,0.530929608,1.06094521,0.886516361,1.270902876,0.687854546,DB1108910013573_,0.374177879,0.059160218,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,docusate,DB11089
,25955,DB11089,10013968,548,9627,369,8038,0.001945987,1.23995455,1.080948742,1.423505037,0.009522529,DB1108910013968_,4.6540948,0.215074726,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,25960,DB00635,10018964,74,32979,79,23715,0.017060576,0.673599393,0.483629188,0.937304307,0.054541138,DB0063510018964_,2.908800044,-0.395119717,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,25962,DB00072,10035664,43,3680,10,325,0.010117352,0.379890045,0.185761917,0.855918255,0.035899515,DB0007210035664_,3.327031486,-0.967873423,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,trastuzumab,DB00072
,25963,DB00390,10035664,243,3902,161,3140,0.063875789,1.21453834,0.985431876,1.500128644,0.150439059,DB0039010035664_,1.894197201,0.194364038,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,digoxin,DB00390
,25964,DB00489,10035664,41,1042,49,1085,0.59066957,0.871318679,0.555927742,1.35958756,0.737232586,DB0048910035664_,0.304851852,-0.137747491,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sotalol,DB00489
,25965,DB00390,10037660,112,4033,77,3224,0.335349294,1.162746097,0.858819226,1.581131369,0.504560937,DB0039010037660_,0.68406666,0.150784533,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,25969,DB00390,10044565,33,4112,24,3277,0.789828911,1.095804635,0.626888961,1.94176826,0.886130966,DB0039010044565_,0.120890522,0.09148892,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,digoxin,DB00390
,25971,DB00635,10044565,248,32805,166,23628,0.484180878,1.076059354,0.879819045,1.318767995,0.648383046,DB0063510044565_,0.433273637,0.073305622,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,25972,DB11089,10044565,97,10078,98,8309,0.169449728,0.816068306,0.608925313,1.093517115,0.310166162,DB1108910044565_,1.170647118,-0.203257219,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,docusate,DB11089
,25973,DB00264,10019909,32,29575,34,24858,0.387139609,0.791072705,0.472453365,1.321663266,0.557266483,DB0026410019909_,0.584711728,-0.2343654,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,25975,DB00381,10019909,39,29321,32,22855,0.904844916,0.950016617,0.579756619,1.567050932,0.957667115,DB0038110019909_,0.043255041,-0.051275803,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,25980,DB00654,10047895,50,3766,56,2542,0.012260089,0.602733238,0.401806946,0.901923601,0.041867797,DB0065410047895_,3.173238308,-0.506280572,NA,10047895,Weight decreased,10022891,Investigations,Inv,latanoprost,DB00654
,25981,DB06403,10028735,986,20485,245,6416,0.001264775,1.26046813,1.091596031,1.459888009,0.006671604,DB0640310028735_,5.009894909,0.231483184,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,25982,DB00635,10052251,61,32992,23,23771,0.007595161,1.910881993,1.165162432,3.23603035,0.028572893,DB0063510052251_,3.555296823,0.647564912,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,25983,DB06403,10052251,58,21413,8,6653,0.028648104,2.252397575,1.069796192,5.465904401,0.0817074,DB0640310052251_,2.504610701,0.811995238,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,25985,DB00451,10005833,160,47111,38,15381,0.082506451,1.374644639,0.959502721,2.014187997,0.182564363,DB0045110005833_,1.700652492,0.318195254,NA,10005833,Blood thyroid stimulating hormone increased,10022891,Investigations,Inv,levothyroxine,DB00451
,25990,DB00497,10001551,68,19199,61,16314,0.790915941,0.947215126,0.660057774,1.361948611,0.886704293,DB0049710001551_,0.120243731,-0.054229046,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,oxycodone,DB00497
,25991,DB00512,10001551,43,4694,65,5033,0.082227091,0.709341442,0.469959669,1.06117872,0.182030496,DB0051210001551_,1.703581045,-0.343418285,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,vancomycin,DB00512
,25992,DB00904,10001551,137,22932,109,14347,0.065674488,0.786361524,0.606428778,1.021707948,0.153615476,DB0090410001551_,1.873302706,-0.240338638,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,ondansetron,DB00904
,25994,DB01225,10001551,76,4968,152,4488,8.56720074691796e-09,0.451724337,0.337356321,0.600693297,1.95476451070085e-07,DB0122510001551_,15.44782592,-0.79468316,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,enoxaparin,DB01225
,25996,DB09153,10001551,48,7751,55,5644,0.027104953,0.635523696,0.421653737,0.954970986,0.078240028,DB0915310001551_,2.547973899,-0.453305902,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,sodium chloride,DB09153
,25997,DB11089,10001551,60,10115,55,8352,0.574666987,0.900774222,0.61350954,1.324796563,0.724362046,DB1108910001551_,0.322463948,-0.104500638,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,docusate,DB11089
,26000,DB00497,10003481,86,19181,70,16305,0.809574547,1.044367178,0.752345035,1.453903413,0.897384007,DB0049710003481_,0.108271407,0.043411131,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,oxycodone,DB00497
,26001,DB00512,10003481,50,4687,62,5036,0.505825644,0.866514129,0.583483816,1.28124018,0.666681395,DB0051210003481_,0.405443016,-0.143276864,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,vancomycin,DB00512
,26002,DB00904,10003481,160,22909,97,14359,0.847064216,1.033872264,0.797675773,1.345819143,0.923260441,DB0090410003481_,0.079843916,0.033311233,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,ondansetron,DB00904
,26004,DB01225,10003481,63,4981,109,4531,5.49978024953606e-05,0.52580418,0.378284806,0.725592531,0.000479078,DB0122510003481_,7.643647568,-0.642826417,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,enoxaparin,DB01225
,26006,DB09153,10003481,54,7745,50,5649,0.232832554,0.787744354,0.525317226,1.183244564,0.389350364,DB0915310003481_,0.943275663,-0.238581666,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,sodium chloride,DB09153
,26007,DB11089,10003481,62,10113,55,8352,0.710288057,0.930993122,0.636244473,1.365403614,0.827200779,DB1108910003481_,0.189707833,-0.071503389,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,docusate,DB11089
,26018,DB00881,10013709,27,685,31,559,0.225461986,0.710956056,0.403001462,1.247228546,0.380242425,DB0088110013709_,0.96694627,-0.341144657,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,quinapril,DB00881
,26021,DB01240,10011224,362,5389,78,1498,0.048205898,1.290028747,1.000239663,1.680875936,0.121735012,DB0124010011224_,2.105908629,0.254664503,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,26033,DB00559,10016322,160,9499,41,3265,0.102752272,1.341297393,0.944156582,1.944132871,0.215155219,DB0055910016322_,1.536395561,0.293637349,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,26034,DB00559,10028997,36,9623,15,3291,0.521039023,0.820775083,0.437633019,1.615842111,0.679998547,DB0055910028997_,0.385664618,-0.197506162,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,bosentan,DB00559
,26035,DB01114,10013700,53,567,10,413,2.77615058345677e-05,3.856306635,1.912770656,8.605980606,0.000265109,DB0111410013700_,8.235371334,1.349709895,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,chlorpheniramine,DB01114
,26036,DB06700,10013700,154,2071,27,591,0.019939864,1.627346212,1.06347864,2.575535596,0.061613981,DB0670010013700_,2.786866465,0.486950597,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,desvenlafaxine,DB06700
,26043,DB13961,10000087,149,9308,67,6347,0.005115223,1.516394793,1.127070706,2.058385018,0.020839063,DB1396110000087_,3.87092604,0.416335671,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,26044,DB01050,10013573,578,17530,238,9133,0.002385561,1.265294594,1.083739584,1.48085927,0.011233335,DB0105010013573_,4.488869553,0.235304976,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,26046,DB00563,10017533,146,46500,40,15308,0.349195606,1.201587627,0.841366356,1.751240684,0.518740906,DB0056310017533_,0.656350739,0.183643705,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,26047,DB01050,10017533,43,18065,9,9362,0.011951418,2.475964106,1.189860099,5.779227389,0.04101887,DB0105010017533_,3.193723063,0.906629858,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,26049,DB00158,10028813,1002,15813,282,7822,1.31275825280031e-17,1.757571595,1.534071484,2.018634452,1.0833862064319e-15,DB0015810028813_,34.45868488,0.563933081,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,26050,DB13961,10028813,624,8833,247,6167,2.98091573451968e-14,1.763748202,1.514029907,2.059555739,1.64090827396544e-12,DB1396110028813_,27.1357712,0.567441204,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,26052,DB00563,10054266,57,46589,12,15336,0.207916811,1.563532869,0.829222009,3.202681774,0.358754496,DB0056310054266_,1.025116979,0.446947921,NA,10054266,Injection site discomfort,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,26056,DB01224,10013754,68,8040,43,5874,0.500040586,1.155324702,0.775975569,1.736932749,0.661711061,DB0122410013754_,0.412926282,0.144381432,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,26058,DB01224,10028813,330,7778,138,5779,9.4192585193736e-09,1.776642861,1.447668545,2.189787616,2.13199642068384e-07,DB0122410028813_,15.36103682,0.57472555,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,quetiapine,DB01224
,26061,DB01224,10039897,98,8010,80,5837,0.491958955,0.892683416,0.656268778,1.217281302,0.65501299,DB0122410039897_,0.423100211,-0.113523279,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,26063,DB01224,10047700,170,7938,86,5831,0.004906764,1.452013757,1.11121998,1.9089007,0.020161682,DB0122410047700_,3.903971404,0.372951391,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,quetiapine,DB01224
,26065,DB00472,10065154,55,10704,19,4293,0.698920038,1.160960939,0.677369145,2.074091062,0.818987281,DB0047210065154_,0.199686725,0.149248057,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,fluoxetine,DB00472
,26071,DB00230,10001949,182,19492,60,8591,0.058144165,1.336862016,0.992276513,1.823188245,0.139942482,DB0023010001949_,1.966523781,0.290325088,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,26072,DB00381,10001949,113,29247,69,22818,0.11615313,1.277683374,0.938269812,1.7505325,0.235359622,DB0038110001949_,1.446640628,0.245048574,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,26073,DB00425,10001949,83,12612,56,7428,0.429306054,0.872937259,0.613769263,1.249603667,0.597831069,DB0042510001949_,0.514447059,-0.135891594,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,26074,DB00656,10001949,48,11965,37,6582,0.139411934,0.713690027,0.45464072,1.128316237,0.269028904,DB0065610001949_,1.312936456,-0.337306547,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,26077,DB00843,10003549,65,2129,98,2075,0.008253453,0.646510745,0.462252316,0.899217309,0.030538012,DB0084310003549_,3.488783072,-0.436165461,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,donepezil,DB00843
,26078,DB00230,10012218,35,19639,21,8630,0.249389563,0.732381345,0.41435741,1.324901823,0.408807904,DB0023010012218_,0.894509906,-0.311453938,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,26079,DB00381,10012218,49,29311,54,22833,0.090657359,0.706875374,0.470002406,1.060818846,0.196249462,DB0038110012218_,1.628368665,-0.346900902,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,26080,DB00425,10012218,47,12648,43,7441,0.037933989,0.64308319,0.415664529,0.99712815,0.10149211,DB0042510012218_,2.287774213,-0.441481185,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,26084,DB00843,10012378,36,2158,25,2148,0.197192086,1.433203442,0.833627835,2.499978846,0.34564996,DB0084310012378_,1.062328692,0.359912108,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,donepezil,DB00843
,26085,DB01409,10012378,76,5955,42,3924,0.39493216,1.192321427,0.805656007,1.78598347,0.564818098,DB0140910012378_,0.57125155,0.175902186,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,tiotropium,DB01409
,26086,DB00230,10022998,137,19537,57,8594,0.754975184,1.057260853,0.770005419,1.468037439,0.862429787,DB0023010022998_,0.14800154,0.055681463,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,26087,DB00381,10022998,54,29306,42,22845,1,1.002256951,0.657029995,1.538167538,1,DB0038110022998_,0,0.002254407,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,26088,DB00425,10022998,50,12645,34,7450,0.57164284,0.866431062,0.548815796,1.382874474,0.72177889,DB0042510022998_,0.326036434,-0.143372733,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,26089,DB00656,10022998,66,11947,50,6569,0.097792175,0.725834516,0.494336221,1.07143935,0.207561418,DB0065610022998_,1.572327991,-0.320433229,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,26092,DB00656,10033295,142,11871,136,6483,4.77945299328817e-06,0.570204191,0.446622912,0.728257776,5.68452135423437e-05,DB0065610033295_,9.775178536,-0.561760752,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,26094,DB01409,10033295,41,5990,27,3939,1,0.998571796,0.598534712,1.691116962,1,DB0140910033295_,0,-0.001429225,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,tiotropium,DB01409
,26095,DB00230,10042464,42,19632,24,8627,0.34862908,0.768995715,0.454745127,1.328568104,0.518148503,DB0023010042464_,0.657493392,-0.262669881,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,26096,DB00425,10042464,83,12612,55,7429,0.536079132,0.888926399,0.623862131,1.275248515,0.692459531,DB0042510042464_,0.367505482,-0.117740838,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,26097,DB00656,10042464,106,11907,54,6565,0.678756652,1.082295473,0.771590226,1.533374311,0.805522658,DB0065610042464_,0.216263948,0.079084224,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,26104,DB08932,10003988,561,18882,122,6475,2.71275278582873e-06,1.576767266,1.291458196,1.937976953,3.46728455995664e-05,DB0893210003988_,10.26955372,0.455376717,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,26105,DB08932,10011224,1395,18048,314,6283,1.94224228298449e-12,1.546629703,1.362677734,1.759597402,8.32140805350403e-11,DB0893210011224_,23.20960455,0.436078179,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,26106,DB08932,10055798,176,19267,68,6529,0.374800402,0.877094473,0.658378597,1.179841122,0.544637122,DB0893210055798_,0.607635538,-0.13114057,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,macitentan,DB08932
,26107,DB09065,10013709,29,723,67,1870,0.643450664,1.119448434,0.691918167,1.771803545,0.779818831,DB0906510013709_,0.248693655,0.112836094,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cobicistat,DB09065
,26109,DB08908,10025327,110,10563,37,3242,0.625393705,0.912461009,0.622069143,1.365639359,0.765024946,DB0890810025327_,0.267846837,-0.091609924,NA,10025327,Lymphopenia,10005329,Blood and lymphatic system disorders,Blood,dimethyl fumarate,DB08908
,26111,DB00005,10052437,48,128034,10,42409,0.22374118,1.589861441,0.794173739,3.525117283,0.378189571,DB0000510052437_,0.9723597,0.463646869,NA,10052437,Nasal discomfort,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,26112,DB00104,10012735,147,1334,101,976,0.684841809,1.064843887,0.809490541,1.404897799,0.809622937,DB0010410012735_,0.21118665,0.062828204,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,octreotide,DB00104
,26113,DB00715,10012735,253,4590,101,2186,0.144796054,1.192937942,0.937912193,1.526512077,0.276737024,DB0071510012735_,1.284687597,0.176419123,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,paroxetine,DB00715
,26121,DB00005,10053262,49,128033,21,42398,0.333325387,0.772682357,0.454742094,1.356624044,0.502362764,DB0000510053262_,0.688432783,-0.257887237,NA,10053262,Skin swelling,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,26122,DB00333,10000081,43,3028,41,3111,0.743120871,1.077487063,0.683742588,1.700210688,0.852985091,DB0033310000081_,0.15901321,0.074631536,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,methadone,DB00333
,26123,DB00433,10000081,220,7436,110,5910,6.50635773392054e-05,1.589508816,1.25529868,2.02217159,0.000551376,DB0043310000081_,7.503094212,0.463425047,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,26124,DB00653,10000081,43,1049,22,800,0.160488103,1.490294625,0.863902538,2.638740163,0.298153853,DB0065310000081_,1.210145642,0.398973835,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,magnesium sulfate,DB00653
,26125,DB01065,10000081,86,4245,37,3014,0.012360457,1.650187629,1.106717289,2.503667639,0.042144844,DB0106510000081_,3.166642917,0.500888996,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,melatonin,DB01065
,26126,DB09037,10000081,53,2473,35,2800,0.013358391,1.71432661,1.09375819,2.717009845,0.044846454,DB0903710000081_,3.104510751,0.539020356,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,pembrolizumab,DB09037
,26127,DB14513,10000081,96,7081,38,3526,0.267891462,1.25791577,0.853581938,1.887210403,0.430266541,DB1451310000081_,0.8433504,0.2294562,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,26128,DB00005,10013950,170,127912,43,42376,0.131453296,1.309737033,0.93233874,1.875854476,0.257815989,DB0000510013950_,1.355509169,0.269826379,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,26130,DB00005,10017822,47,128035,12,42407,0.546517339,1.297241555,0.677490714,2.686865233,0.701169408,DB0000510017822_,0.355005754,0.260240129,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,26131,DB00005,10026865,206,127876,68,42351,1,1.003305051,0.759092093,1.340269956,1,DB0000510026865_,0,0.003299602,NA,10026865,Mass,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,26148,DB06643,10038695,47,52374,14,7501,0.01982835,0.480812898,0.260116569,0.946143559,0.061347836,DB0664310038695_,2.791195385,-0.732277069,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,denosumab,DB06643
,26150,DB06285,10037844,170,8680,20,1086,0.907206681,1.063479511,0.663885985,1.793070815,0.958649525,DB0628510037844_,0.04222973,0.06154609,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,teriparatide,DB06285
,26151,DB00398,10037087,31,696,52,1486,0.337728121,1.272640178,0.780948041,2.043851137,0.506838187,DB0039810037087_,0.679563485,0.241093623,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,sorafenib,DB00398
,26152,DB00398,10047895,48,679,122,1416,0.305270318,0.82053723,0.567623015,1.170728204,0.472108375,DB0039810047895_,0.750546712,-0.197795995,NA,10047895,Weight decreased,10022891,Investigations,Inv,sorafenib,DB00398
,26153,DB00398,10061428,52,675,150,1388,0.048119916,0.712950432,0.502874753,0.997935607,0.12156586,DB0039810061428_,2.107299108,-0.338343382,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,sorafenib,DB00398
,26157,DB00541,10002034,112,3022,165,4132,0.577075447,0.928104333,0.720100914,1.192752076,0.726231208,DB0054110002034_,0.319886846,-0.074611125,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,vincristine,DB00541
,26158,DB00541,10047942,44,3090,97,4200,0.007560459,0.61659398,0.420300256,0.892184457,0.028472908,DB0054110047942_,3.558802232,-0.483544526,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,vincristine,DB00541
,26161,DB00950,10002034,51,4667,25,2031,0.617493488,0.887796638,0.538250056,1.499747372,0.758467083,DB0095010002034_,0.276455879,-0.119012574,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,fexofenadine,DB00950
,26162,DB08895,10002034,176,27938,36,6610,0.483435036,1.156682902,0.803571966,1.70671623,0.6476682,DB0889510002034_,0.434376751,0.145556341,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,tofacitinib,DB08895
,26163,DB00213,10017955,275,18620,278,13143,3.40369041230941e-05,0.698257736,0.587960792,0.829195124,0.00031708,DB0021310017955_,8.056357361,-0.359166995,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,26165,DB08895,10017955,46,28068,15,6631,0.257868743,0.724500916,0.39691266,1.397974599,0.418761887,DB0889510017955_,0.87045281,-0.322272253,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,26166,DB00338,10008629,76,33598,52,22220,0.856911239,0.966566976,0.670123697,1.403742759,0.93133668,DB0033810008629_,0.071134435,-0.034004686,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,omeprazole,DB00338
,26171,DB00722,10008629,62,25341,51,25981,0.259089718,1.246380896,0.846202964,1.843062313,0.420186533,DB0072210008629_,0.86705654,0.220244069,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,lisinopril,DB00722
,26175,DB00338,10017626,54,33620,32,22240,0.660464641,1.116322448,0.707722681,1.787109498,0.79272646,DB0033810017626_,0.232277061,0.110039754,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,omeprazole,DB00338
,26180,DB00722,10017626,32,25371,26,26006,0.431074633,1.261564772,0.728209078,2.204687659,0.599497195,DB0072210017626_,0.511663984,0.232352833,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,lisinopril,DB00722
,26186,DB00207,10033371,292,8788,76,5379,2.5156855288378e-12,2.351563861,1.816670021,3.075158612,1.0605420068244e-10,DB0020710033371_,22.96707083,0.855080579,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,26187,DB05812,10013709,11,171,382,7571,0.384422735,1.274886481,0.61923831,2.365714505,0.554482888,DB0581210013709_,0.589719334,0.24285714,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,abiraterone,DB05812
,26197,DB01075,10002757,46,19902,11,11086,0.008415484,2.329338339,1.187920334,4.989762842,0.031013109,DB0107510002757_,3.473345299,0.845584253,NA,10002757,Anticholinergic syndrome,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,26199,DB00788,10022523,64,9292,39,5022,0.604595165,0.886928265,0.585573426,1.3587669,0.747842343,DB0078810022523_,0.290563095,-0.119991173,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,26200,DB00215,10040108,98,11005,85,5191,6.17411213864139e-05,0.54383107,0.401776967,0.737423315,0.000528427,DB0021510040108_,7.545606442,-0.609116614,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,26201,DB00316,10040108,79,65395,52,36901,0.41282142,0.857277045,0.596410676,1.241367877,0.582213871,DB0031610040108_,0.540917423,-0.15399414,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,26203,DB01075,10040108,37,19911,30,11067,0.12701892,0.68555402,0.411838437,1.149654898,0.251469855,DB0107510040108_,1.380432158,-0.377527979,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,26204,DB01156,10040108,86,13536,150,6178,8.2975241218124e-24,0.261701299,0.198014372,0.344016018,1.18211610591783e-21,DB0115610040108_,48.18698081,-1.340551505,male,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,26205,DB00215,10042464,62,11041,40,5236,0.136995343,0.735051613,0.485398115,1.124425309,0.265496025,DB0021510042464_,1.326155408,-0.30781456,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,26206,DB00788,10042464,41,9315,23,5038,0.896029693,0.96414974,0.564346214,1.685176556,0.956301489,DB0078810042464_,0.044682051,-0.036508664,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,naproxen,DB00788
,26207,DB01075,10042464,88,19860,36,11061,0.132938234,1.361417013,0.913332175,2.067676359,0.259865503,DB0107510042464_,1.347591076,0.308526079,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,26208,DB01156,10042464,134,13488,46,6282,0.076959475,1.356763108,0.962458193,1.942908088,0.17308803,DB0115610042464_,1.753954968,0.305101795,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,26210,DB01409,10047513,43,5988,33,3933,0.556495919,0.855865566,0.530140532,1.393127685,0.709865827,DB0140910047513_,0.342679303,-0.155641964,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,tiotropium,DB01409
,26211,DB00374,10005724,122,17594,27,5697,0.084491482,1.463060373,0.956932209,2.312442107,0.185853685,DB0037410005724_,1.682795556,0.380530388,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,treprostinil,DB00374
,26213,DB08932,10007617,44,19399,17,6580,0.658879696,0.877930824,0.491160413,1.640206377,0.791655557,DB0893210007617_,0.233628884,-0.130187476,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,macitentan,DB08932
,26214,DB08932,10009033,312,19131,139,6458,0.008658236,0.757713728,0.617153435,0.934053245,0.031731978,DB0893210009033_,3.450430352,-0.277449633,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,26219,DB00331,10021036,50,24896,76,20676,0.000865383,0.54639271,0.374335542,0.791421179,0.004890691,DB0033110021036_,5.320421732,-0.604417314,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,26222,DB00982,10024552,86,3278,82,2019,0.006043565,0.646046526,0.469242376,0.889914544,0.023798518,DB0098210024552_,3.738131967,-0.436883756,NA,10024552,Lip dry,10017947,Gastrointestinal disorders,Gastr,isotretinoin,DB00982
,26227,DB00682,10048865,52,19407,47,16317,0.76216919,0.930238196,0.61449215,1.411485604,0.868271016,DB0068210048865_,0.141251382,-0.072314601,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,warfarin,DB00682
,26230,DB01080,10047555,32,2027,41,2071,0.347808464,0.79747454,0.48399909,1.303529426,0.517367673,DB0108010047555_,0.659001491,-0.226305369,NA,10047555,Visual field defect,10015919,Eye disorders,Eye,vigabatrin,DB01080
,26231,DB00695,10033318,360,27689,175,20353,5.55780385631269e-06,1.512103357,1.257551617,1.823685546,6.48410449903147e-05,DB0069510033318_,9.643571745,0.413501633,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,furosemide,DB00695
,26232,DB00820,10033318,442,11473,145,5671,1.68744300539031e-05,1.506702562,1.242730817,1.835408285,0.000171916,DB0082010033318_,8.668502061,0.40992353,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,tadalafil,DB00820
,26233,DB06403,10033318,445,21026,139,6522,0.960770306,0.993046094,0.817312991,1.212699541,0.998333629,DB0640310033318_,0.001667761,-0.006978197,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,ambrisentan,DB06403
,26234,DB00820,10021143,217,11698,90,5726,0.198195663,1.180176133,0.916954426,1.52947632,0.346877052,DB0082010021143_,1.058784879,0.165663693,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,26235,DB08932,10021143,412,19031,181,6416,0.004115815,0.767407658,0.641252297,0.92125429,0.01748149,DB0893210021143_,4.046612652,-0.264737122,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,26236,DB01273,10002855,76,1964,42,1233,0.563670576,1.136008412,0.763722525,1.709638494,0.715579864,DB0127310002855_,0.334662067,0.127520726,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,varenicline,DB01273
,26237,DB01060,10020751,144,8443,50,5031,0.000944005,1.716065218,1.233362904,2.422127918,0.005252574,DB0106010020751_,5.249036996,0.540034006,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,amoxicillin,DB01060
,26239,DB01307,10007559,24,2500,38,2031,0.010199017,0.513176402,0.293426381,0.881237007,0.036124669,DB0130710007559_,3.320779293,-0.66713563,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,insulin detemir,DB01307
,26240,DB01098,10012601,45,8104,32,7177,0.361705384,1.24537281,0.773172162,2.02717991,0.531467719,DB0109810012601_,0.632112818,0.219434931,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,rosuvastatin,DB01098
,26243,DB00243,10013573,62,1192,101,1525,0.166644233,0.785416838,0.55773271,1.098827176,0.30630905,DB0024310013573_,1.183160718,-0.241540699,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ranolazine,DB00243
,26247,DB00635,10042254,45,33008,83,23711,2.00086322102828e-07,0.389466873,0.264641049,0.566703433,3.39636356246228e-06,DB0063510042254_,12.59280524,-0.942976467,NA,10042254,Strongyloidiasis,10021881,Infections and infestations,Infec,prednisone,DB00635
,26249,DB00273,10069326,40,8441,13,2180,0.494790274,0.794674559,0.415485108,1.622341768,0.657228907,DB0027310069326_,0.419722909,-0.229822607,NA,10069326,Product substitution issue,10077536,Product issues,Prod,topiramate,DB00273
,26250,DB00437,10005851,28,6893,40,11506,0.532346972,1.168443411,0.693542352,1.943715385,0.689161749,DB0043710005851_,0.372279276,0.155672445,NA,10005851,Blood urea increased,10022891,Investigations,Inv,allopurinol,DB00437
,26252,DB00437,10021097,178,6743,312,11234,0.603280236,0.950486239,0.784150552,1.149249264,0.746988853,DB0043710021097_,0.291705016,-0.050781595,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,allopurinol,DB00437
,26254,DB00437,10037844,191,6730,343,11203,0.414643563,0.926949415,0.770500627,1.112620522,0.583859542,DB0043710037844_,0.538094836,-0.075856284,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,26256,DB00437,10060795,17,6904,39,11507,0.333231236,0.726528888,0.385070247,1.315932723,0.502278466,DB0043710060795_,0.6886006,-0.319477033,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,allopurinol,DB00437
,26257,DB00563,10016334,111,46535,16,15332,0.000921897,2.28553254,1.346571081,4.138909483,0.005154661,DB0056310016334_,5.267853915,0.826599056,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,26260,DB00421,10028735,170,8733,21,5231,3.40371557218333e-16,4.848493752,3.067461138,8.046936826,2.39857007546485e-14,DB0042110028735_,31.36131854,1.57866809,female,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,26261,DB00641,10028735,109,14015,50,12425,8.47917236822586e-05,1.932627035,1.369350471,2.760607318,0.000693235,DB0064110028735_,7.274141541,0.658880236,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,26262,DB01409,10028735,79,5952,36,3930,0.068735587,1.448900611,0.963050762,2.217615947,0.159041804,DB0140910028735_,1.838588193,0.37080507,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,26263,DB00820,10017955,142,11773,65,5751,0.709925239,1.067159179,0.788846984,1.456758944,0.827036771,DB0082010017955_,0.189906122,0.065000145,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,26268,DB00813,10037844,182,10390,93,10075,3.84110835173015e-07,1.897590927,1.467770816,2.466877063,6.09499142923193e-06,DB0081310037844_,12.0080432,0.640585149,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,fentanyl,DB00813
,26275,DB08895,10000087,458,27656,53,6593,8.2200138736457e-08,2.060004142,1.545537841,2.79572412,1.51410697034882e-06,DB0889510000087_,13.40068475,0.722707993,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,26276,DB08895,10012174,74,28040,18,6628,0.894557302,0.97176887,0.574112155,1.730085736,0.955948677,DB0889510012174_,0.045051053,-0.028637291,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,tofacitinib,DB08895
,26287,DB00285,10012374,67,10884,16,3702,0.254101083,1.424241874,0.815178,2.636697622,0.414693094,DB0028510012374_,0.880216565,0.353639654,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,26288,DB00635,10012374,82,32971,27,23767,0.00028355,2.189189029,1.401450965,3.519826536,0.001928108,DB0063510012374_,6.251215943,0.783531169,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,26291,DB13961,10012374,46,9411,15,6399,0.012513299,2.085079496,1.142056455,4.024396289,0.042572102,DB1396110012374_,3.156556113,0.734806982,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,fish oil,DB13961
,26292,DB00794,10016256,58,778,32,577,0.225247851,1.343961844,0.845756246,2.168913414,0.380133266,DB0079410016256_,0.967233388,0.295621852,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,primidone,DB00794
,26294,DB00158,10020765,35,16780,22,8082,0.324762996,0.766291076,0.436792322,1.372176749,0.493205186,DB0015810020765_,0.706829993,-0.266193187,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,26296,DB00273,10020765,46,8435,11,2182,1,1.081744368,0.550806565,2.319976981,1,DB0027310020765_,0,0.078574894,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,26297,DB00285,10020765,36,10915,16,3702,0.42388146,0.763139223,0.412266391,1.474724489,0.592660665,DB0028510020765_,0.523133279,-0.270314797,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,26298,DB00635,10020765,50,33003,26,23768,0.200894761,1.384946791,0.845538486,2.318490973,0.350039361,DB0063510020765_,1.049709671,0.325661721,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,26303,DB00158,10022067,79,16736,26,8078,0.095183246,1.466559543,0.930233417,2.382631172,0.203480266,DB0015810022067_,1.592186251,0.382919211,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,26311,DB00273,10022095,42,8439,8,2185,0.487656463,1.359271198,0.629225567,3.357180056,0.651422988,DB0027310022095_,0.428596096,0.306948672,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,26312,DB00285,10022095,58,10893,10,3708,0.049400716,1.974361092,0.999112537,4.337253975,0.123896552,DB0028510022095_,2.08830832,0.680244848,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,26313,DB00635,10022095,271,32782,46,23748,6.05656582000953e-26,4.267673073,3.111202713,5.97002935,9.94980203618441e-24,DB0063510022095_,52.96448958,1.451068731,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,26316,DB13961,10022095,99,9358,17,6397,2.72633034169617e-09,3.980588435,2.361894716,7.111976388,6.94395281312827e-08,DB1396110022095_,16.48280956,1.381429656,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,26317,DB00153,10044565,78,7345,39,3400,0.690263449,0.925808473,0.621149509,1.400040317,0.813157412,DB0015310044565_,0.206830569,-0.077087899,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,26318,DB00158,10044565,117,16698,62,8042,0.575207339,0.908859927,0.661618513,1.258884247,0.7246849,DB0015810044565_,0.322018339,-0.095564292,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,26319,DB00177,10044565,43,4757,21,2829,0.517450273,1.217652529,0.705245214,2.164936209,0.677029315,DB0017710044565_,0.390040705,0.196924848,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,valsartan,DB00177
,26320,DB00273,10044565,123,8358,32,2161,1,0.993820012,0.666753798,1.520415574,1,DB0027310044565_,0,-0.006199164,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,26321,DB00285,10044565,190,10761,57,3661,0.460658734,1.134021841,0.83720602,1.55651817,0.627980957,DB0028510044565_,0.465245436,0.125770465,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,26322,DB00563,10044565,124,46522,54,15294,0.097923055,0.754905907,0.543894361,1.059967159,0.207749102,DB0056310044565_,1.571424169,-0.281162164,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,26336,DB00958,10000081,188,4406,54,2531,4.30024633853023e-06,1.999739963,1.464085953,2.770542963,5.17190459886832e-05,DB0095810000081_,9.86968445,0.693017153,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,carboplatin,DB00958
,26337,DB01590,10000081,89,4649,66,2801,0.209849617,0.812487929,0.582163242,1.138711937,0.360976223,DB0159010000081_,1.018943186,-0.207654221,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,everolimus,DB01590
,26338,DB00958,10016173,52,4542,25,2560,0.552585322,1.172351204,0.712464774,1.97666072,0.706385817,DB0095810016173_,0.347593707,0.159011308,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,carboplatin,DB00958
,26341,DB00203,10035598,202,13676,88,8850,0.001970815,1.485406918,1.149152984,1.933221671,0.009617168,DB0020310035598_,4.644205485,0.395688753,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,26342,DB00559,10035598,96,9563,38,3268,0.427313302,0.863357772,0.585857648,1.295170081,0.595890008,DB0055910035598_,0.517699178,-0.146926106,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,26343,DB00559,10042609,39,9620,17,3289,0.44190908,0.784353731,0.432739121,1.480786573,0.610013926,DB0055910042609_,0.494273492,-0.242895173,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,bosentan,DB00559
,26344,DB00203,10008190,103,13775,85,8853,0.098654828,0.778803919,0.577932416,1.051848412,0.208846468,DB0020310008190_,1.566155902,-0.249995973,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,26345,DB00559,10008190,110,9549,26,3280,0.092736444,1.453156266,0.938865432,2.326573937,0.199621442,DB0055910008190_,1.611332496,0.373737926,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,bosentan,DB00559
,26353,DB01409,10012174,68,5963,48,3918,0.703665136,0.930830718,0.632389054,1.379572332,0.822250872,DB0140910012174_,0.195709734,-0.071677847,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,tiotropium,DB01409
,26358,DB00331,10002198,59,24887,24,20728,0.002699733,2.047441173,1.253731626,3.44293559,0.012403858,DB0033110002198_,4.389747731,0.716590805,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,metformin,DB00331
,26359,DB00641,10002198,29,14095,33,12442,0.372705969,0.775738395,0.454103669,1.318569504,0.542420951,DB0064110002198_,0.611712916,-0.253939935,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,simvastatin,DB00641
,26360,DB01104,10002198,57,15406,10,7276,0.00228112,2.691919426,1.361467564,5.916829288,0.01082981,DB0110410002198_,4.525452727,0.99025448,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,sertraline,DB01104
,26361,DB00331,10002424,84,24862,78,20674,0.527299049,0.895518501,0.649712226,1.235531922,0.684888569,DB0033110002424_,0.378499127,-0.110352398,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,26363,DB00641,10021097,264,13860,236,12239,0.892169328,0.987811652,0.824156519,1.184522677,0.955096007,DB0064110021097_,0.045943412,-0.012263235,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,simvastatin,DB00641
,26364,DB00331,10033775,244,24702,95,20657,4.83901706401146e-11,2.147755412,1.686555693,2.753991167,1.66059919312203e-09,DB0033110033775_,20.21608734,0.764423302,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,metformin,DB00331
,26365,DB00641,10033775,144,13980,70,12405,2.52089679397739e-05,1.825336905,1.361131895,2.467434934,0.000243296,DB0064110033775_,8.32123014,0.601764575,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,26366,DB01104,10033775,168,15295,40,7246,4.92114391968981e-05,1.989695578,1.400405597,2.887415144,0.000435823,DB0110410033775_,7.738274349,0.687981651,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,26367,DB00331,10042727,61,24885,27,20725,0.005264109,1.881532192,1.177397966,3.080538526,0.021308554,DB0033110042727_,3.848646675,0.63208644,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,26368,DB00641,10042727,44,14080,16,12459,0.001699585,2.433221646,1.345346171,4.621841491,0.008503586,DB0064110042727_,4.767267288,0.889216159,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,26369,DB00722,10042727,124,25279,167,25865,0.021763922,0.75973362,0.596921618,0.964865185,0.066077355,DB0072210042727_,2.716929179,-0.274787407,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,26371,DB00331,10042772,132,24814,159,20593,0.001708962,0.688981853,0.54236631,0.873998384,0.008543998,DB0033110042772_,4.762526174,-0.372540347,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,metformin,DB00331
,26372,DB00722,10042772,181,25222,236,25796,0.015875209,0.7844088,0.642176172,0.956837776,0.051531939,DB0072210042772_,2.965553487,-0.242824965,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,26373,DB00316,10047461,193,65281,90,36863,0.137280445,1.210889244,0.937812203,1.573522165,0.265941067,DB0031610047461_,1.324480546,0.191355002,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,26374,DB00331,10047461,38,24908,29,20723,0.80632706,1.090212073,0.654541653,1.833590537,0.895294503,DB0033110047461_,0.110602561,0.08637224,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,metformin,DB00331
,26376,DB00722,10047461,63,25340,44,25988,0.05294356,1.468413903,0.983019346,2.210692433,0.130552227,DB0072210047461_,2.035981923,0.384182841,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,lisinopril,DB00722
,26378,DB01104,10047700,500,14963,142,7144,2.14614706391133e-08,1.681106997,1.389425417,2.044516146,4.4717776912334e-07,DB0110410047700_,14.62030963,0.519452503,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,26383,DB05259,10044565,208,11062,53,2675,0.752308425,0.949022041,0.696645655,1.312598393,0.860395831,DB0525910044565_,0.150362727,-0.052323256,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,26385,DB01164,10066366,76,6448,45,7891,0.00010227,2.066762137,1.408832314,3.063000691,0.000813609,DB0116410066366_,7.114030994,0.725983198,NA,10066366,Toxic anterior segment syndrome,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium chloride,DB01164
,26386,DB00047,10012607,94,9191,98,8420,0.384113739,0.878728384,0.653975334,1.180167552,0.554170352,DB0004710012607_,0.590283146,-0.129279435,NA,10012607,Diabetes mellitus inadequate control,10027433,Metabolism and nutrition disorders,Metab,insulin glargine,DB00047
,26387,DB00047,10021789,68,9217,67,8451,0.729577968,0.930603176,0.653323603,1.325827057,0.842472184,DB0004710021789_,0.171414633,-0.071922327,NA,10021789,Infection,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,26389,DB00005,10016059,86,127996,11,42408,0.001362695,2.590455201,1.377639388,5.382479202,0.007106835,DB0000510016059_,4.946698283,0.951833614,NA,10016059,Facial pain,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,26390,DB00005,10017885,264,127818,69,42350,0.086478547,1.2676881,0.968977666,1.677753694,0.18914821,DB0000510017885_,1.665224392,0.237194848,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,26391,DB00005,10023644,146,127936,51,42368,0.741746576,0.948038608,0.684713553,1.331275921,0.851965687,DB0000510023644_,0.160209027,-0.053360052,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,etanercept,DB00005
,26392,DB00005,10048908,154,127928,56,42363,0.576039981,0.910644969,0.666471688,1.259948658,0.725422742,DB0000510048908_,0.321000701,-0.093602174,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,etanercept,DB00005
,26393,DB00374,10008479,955,16761,213,5511,2.22035606568034e-07,1.474114094,1.265256591,1.723723909,3.72562929492982e-06,DB0037410008479_,12.50027478,0.388057195,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,26394,DB00203,10065154,92,13786,64,8874,0.680840571,0.925317668,0.664515087,1.295230422,0.807023985,DB0020310065154_,0.21440189,-0.077618176,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,26396,DB00046,10012601,44,5415,42,4650,0.664575525,0.899627495,0.574755368,1.409833155,0.795843536,DB0004610012601_,0.228352676,-0.105774496,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,insulin lispro,DB00046
,26397,DB00331,10012601,186,24760,163,20589,0.627661791,0.948850024,0.764105039,1.179269359,0.767039846,DB0033110012601_,0.265216529,-0.052504529,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,26398,DB00335,10012601,41,8425,25,5440,0.899703535,1.058946281,0.62793641,1.819213194,0.956571579,DB0033510012601_,0.044399659,0.057274339,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,atenolol,DB00335
,26399,DB00381,10012601,103,29257,88,22799,0.559091851,0.912098257,0.679169271,1.227113524,0.711840552,DB0038110012601_,0.339901337,-0.092007557,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,26401,DB00722,10012601,119,25284,99,25933,0.135273406,1.232866586,0.935819524,1.627183335,0.263080276,DB0072210012601_,1.33529606,0.209342015,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,26402,DB00335,10047700,279,8187,101,5364,2.038055086549e-07,1.809791107,1.432353207,2.301668183,3.45169316687761e-06,DB0033510047700_,12.57664567,0.593211428,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,26403,DB00046,10061024,27,5432,30,4662,0.352929248,0.772446456,0.441164571,1.346579454,0.522693942,DB0004610061024_,0.648759183,-0.258192585,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,insulin lispro,DB00046
,26413,DB00559,10033318,255,9404,102,3204,0.175985666,0.851800123,0.671939065,1.086371183,0.318645949,DB0055910033318_,1.143674671,-0.160403377,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,bosentan,DB00559
,26423,DB01050,10069868,140,17968,11,9360,8.01030810427541e-15,6.63013997,3.591015625,13.58891906,4.77439792564352e-13,DB0105010069868_,28.37033833,1.891625916,female,10069868,Device issue,10077536,Product issues,Prod,ibuprofen,DB01050
,26424,DB00395,10016173,85,2099,11,725,0.001114639,2.668126921,1.408221812,5.578528922,0.006022256,DB0039510016173_,5.112293271,0.981376699,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,carisoprodol,DB00395
,26425,DB00588,10016173,528,15996,186,8282,5.54243307053701e-06,1.469733091,1.23844296,1.750335408,6.47047982496403e-05,DB0058810016173_,9.645675198,0.385080813,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,26426,DB00736,10016173,302,10289,108,5445,0.000494494,1.479782724,1.180945196,1.865701056,0.003063345,DB0073610016173_,5.788247744,0.391895269,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,esomeprazole,DB00736
,26428,DB01394,10016173,56,1384,43,1960,0.003586221,1.843952523,1.209382833,2.828655887,0.015620739,DB0139410016173_,4.159155796,0.611911378,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,colchicine,DB01394
,26429,DB06413,10016173,94,1462,28,646,0.084300094,1.483145533,0.952541527,2.374444292,0.18557246,DB0641310016173_,1.684309852,0.394165193,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,armodafinil,DB06413
,26433,DB00497,10023469,41,19226,24,16351,0.170458456,1.452855915,0.856858243,2.514761767,0.311479381,DB0049710023469_,1.166422135,0.373531216,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,oxycodone,DB00497
,26435,DB00695,10023469,56,27993,10,20518,3.99081396893531e-06,4.104497268,2.074310579,9.025932311,4.84967846386799e-05,DB0069510023469_,9.934013058,1.412083267,female,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,furosemide,DB00695
,26442,DB00395,10033371,138,2046,27,709,0.007196097,1.770858779,1.154079135,2.808567926,0.027370732,DB0039510033371_,3.598281021,0.571464615,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,carisoprodol,DB00395
,26443,DB00497,10033371,963,18304,590,15785,1.17092554234703e-10,1.407562096,1.2662496,1.565586596,3.77409906567647e-09,DB0049710033371_,19.39510414,0.341859198,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,26444,DB00930,10033371,41,1249,14,628,0.246668142,1.472216966,0.779146478,2.947018883,0.405723982,DB0093010033371_,0.902082197,0.386769405,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,colesevelam,DB00930
,26445,DB01394,10033371,64,1376,38,1965,2.28307470722537e-05,2.404533246,1.574787826,3.715499323,0.000223712,DB0139410033371_,8.405153136,0.877355808,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,colchicine,DB01394
,26446,DB06413,10033371,62,1494,31,643,0.49125179,0.860847709,0.544715008,1.385119871,0.654429745,DB0641310033371_,0.423991041,-0.149837667,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,armodafinil,DB06413
,26447,DB09072,10033371,201,6270,40,2495,3.11427858533963e-05,1.999450512,1.413291844,2.891679736,0.000293348,DB0907210033371_,8.13415029,0.692872399,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,26448,DB14500,10033371,310,7499,94,3979,1.11848660403713e-06,1.749788586,1.380176667,2.23551462,1.57934033774461e-05,DB1450010033371_,11.05591821,0.559494973,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,26449,DB00230,10060820,59,19615,22,8629,0.548003898,1.179764231,0.711597612,2.023456817,0.702539216,DB0023010060820_,0.353054056,0.165314614,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,26453,DB00588,10060820,45,16479,16,8452,0.225174654,1.442497834,0.799262644,2.735759833,0.380045916,DB0058810060820_,0.967463202,0.366376218,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,26454,DB00695,10060820,70,27979,26,20502,0.002561096,1.972786738,1.241029311,3.225846886,0.011886364,DB0069510060820_,4.432363456,0.679447131,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,26461,DB00813,10035226,98,10474,107,10061,0.362621895,0.879779579,0.661038362,1.169829307,0.53220767,DB0081310035226_,0.630721509,-0.128083881,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fentanyl,DB00813
,26462,DB00999,10035226,81,21349,78,12161,0.001197691,0.591577106,0.427672996,0.818586167,0.006398641,DB0099910035226_,5.051669637,-0.524963248,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,hydrochlorothiazide,DB00999
,26478,DB01050,10048302,37,18071,35,9336,0.012302551,0.546139438,0.334408578,0.893673425,0.041984185,DB0105010048302_,3.170462269,-0.604880954,NA,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,ibuprofen,DB01050
,26480,DB01076,10048302,21,25726,48,25535,0.001050091,0.434234321,0.246905078,0.739545532,0.005738984,DB0107610048302_,5.160473028,-0.83417098,NA,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,26487,DB00390,10011906,312,3833,268,3033,0.360765393,0.921209542,0.774414106,1.096324674,0.530679856,DB0039010011906_,0.633596347,-0.082067753,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,26488,DB14500,10011906,377,7432,281,3792,3.93562292428074e-06,0.684537072,0.582024712,0.805840984,4.7883063437886e-05,DB1450010011906_,9.946748698,-0.379012477,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,26489,DB00153,10051398,27,7396,45,3394,7.37299010216533e-08,0.275375018,0.164007268,0.454376553,1.37348720648771e-06,DB0015310051398_,13.49815765,-1.289621407,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ergocalciferol,DB00153
,26491,DB00331,10051398,74,24872,106,20646,0.000301535,0.579511646,0.424423499,0.787699644,0.00202655,DB0033110051398_,6.201420535,-0.545569521,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metformin,DB00331
,26493,DB00761,10051398,64,15243,71,8554,9.65117060999443e-05,0.505850352,0.354707416,0.720158,0.000772711,DB0076110051398_,7.165605454,-0.6815144,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,potassium chloride,DB00761
,26495,DB01137,10051398,29,7743,31,5562,0.148548177,0.672016045,0.39025026,1.154096713,0.281986184,DB0113710051398_,1.265897202,-0.397473063,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levofloxacin,DB01137
,26504,DB01190,10000081,74,4860,28,2257,0.392291756,1.227293154,0.782218842,1.97555983,0.562173634,DB0119010000081_,0.575944519,0.204811056,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,clindamycin,DB01190
,26508,DB00060,10025482,244,9264,45,2420,0.032612553,1.416376251,1.023557185,1.99899803,0.090448004,DB0006010025482_,2.402980131,0.348101674,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,26509,DB00005,10014184,116,127966,36,42383,0.778929306,1.067211075,0.728484843,1.597731433,0.879549652,DB0000510014184_,0.128345261,0.065048773,NA,10014184,Eczema,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,26514,DB08908,10008531,50,10623,11,3268,0.365723588,1.398289684,0.717473738,2.982330299,0.535321983,DB0890810008531_,0.624886877,0.335249836,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,26517,DB00455,10002198,50,9351,12,5106,0.007567833,2.275044991,1.19326958,4.697325604,0.028494555,DB0045510002198_,3.55804227,0.821999828,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,loratadine,DB00455
,26518,DB00471,10002198,161,14028,39,5426,0.00864635,1.596796415,1.117700772,2.330962601,0.031697254,DB0047110002198_,3.451525219,0.467999381,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,montelukast,DB00471
,26519,DB00788,10002198,34,9322,18,5043,1,1.021847039,0.560492849,1.923929524,1,DB0078810002198_,0,0.021611813,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,naproxen,DB00788
,26522,DB00316,10038683,112,65362,64,36889,0.937508807,0.987661017,0.71992488,1.364998689,0.977485878,DB0031610038683_,0.022771434,-0.01241574,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,26525,DB00471,10038683,47,14142,15,5450,0.573245007,1.207493969,0.662744647,2.326859265,0.723184315,DB0047110038683_,0.324091159,0.188547112,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,26526,DB00588,10038683,47,16477,23,8445,0.900067383,1.047346913,0.622858289,1.808366506,0.95659897,DB0058810038683_,0.044371025,0.046260217,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,26532,DB00316,10040831,118,65356,45,36908,0.027218119,1.480822061,1.041851207,2.137328601,0.078484808,DB0031610040831_,2.544850202,0.39259738,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,26545,DB00338,10012601,122,33552,87,22185,0.620364759,0.927219373,0.698114977,1.23589494,0.760909365,DB0033810012601_,0.273241028,-0.075565093,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,26546,DB00863,10012601,35,10638,23,5817,0.494120272,0.832126865,0.477461759,1.476544056,0.656739251,DB0086310012601_,0.420468218,-0.183770368,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,ranitidine,DB00863
,26547,DB00999,10012601,83,21347,45,12194,0.854018645,1.053600318,0.723885821,1.551080722,0.928913404,DB0099910012601_,0.073739759,0.052213174,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,26551,DB01015,10011781,41,9846,16,9365,0.002031348,2.437045818,1.337226566,4.655471871,0.009846747,DB0101510011781_,4.620614143,0.890786575,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,26555,DB01015,10037153,24,9863,33,9348,0.184983242,0.689315341,0.389512632,1.203190167,0.33012761,DB0101510037153_,1.108276001,-0.372056433,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,26580,DB00264,10047302,58,29549,124,24768,1.33683151488564e-09,0.392066983,0.281834906,0.5399717,3.62440602050221e-08,DB0026410047302_,17.13299033,-0.936322579,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,metoprolol,DB00264
,26581,DB00421,10047302,37,8866,34,5218,0.064891984,0.640518845,0.390553565,1.053321193,0.152272981,DB0042110047302_,1.882080441,-0.445476736,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,spironolactone,DB00421
,26582,DB00451,10047302,33,47238,39,15380,1.08632548519667e-07,0.275506377,0.167850882,0.44971248,1.95575790262975e-06,DB0045110047302_,13.14473277,-1.289144504,male,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,26584,DB00682,10047302,34,19425,50,16314,0.011577453,0.571111292,0.357988963,0.901141138,0.040036126,DB0068210047302_,3.21797307,-0.560171181,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,warfarin,DB00682
,26588,DB00684,10011906,135,2657,141,2207,0.07151497,0.795329642,0.619072586,1.021421625,0.163900164,DB0068410011906_,1.808497792,-0.228998607,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tobramycin,DB00684
,26589,DB00999,10013709,1010,20420,532,11707,0.122532161,1.088437307,0.976505952,1.214162138,0.245064323,DB0099910013709_,1.406234561,0.084743005,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,26590,DB00682,10037423,217,19242,98,16266,1.43304209016037e-07,1.871762117,1.466513722,2.403344113,2.51788177405516e-06,DB0068210037423_,12.89209258,0.626880296,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,26591,DB00060,10028997,60,9448,11,2454,0.376182502,1.416702974,0.736551672,2.993221104,0.545949097,DB0006010028997_,0.605229537,0.348332323,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,interferon beta-1a,DB00060
,26592,DB00047,10005169,37,9248,33,8485,1,1.028710478,0.62524644,1.699100287,1,DB0004710005169_,0,0.028306055,NA,10005169,Blindness,10015919,Eye disorders,Eye,insulin glargine,DB00047
,26606,DB00996,10005169,55,38898,40,22385,0.286314379,0.791301292,0.516884107,1.220935739,0.451063769,DB0099610005169_,0.796146556,-0.234076484,NA,10005169,Blindness,10015919,Eye disorders,Eye,gabapentin,DB00996
,26608,DB01076,10005169,40,25707,33,25550,0.482639859,1.204712392,0.740508907,1.972118953,0.646990448,DB0107610005169_,0.435423749,0.186240859,NA,10005169,Blindness,10015919,Eye disorders,Eye,atorvastatin,DB01076
,26613,DB00046,10005483,37,5422,50,4642,0.039831359,0.633580522,0.401886767,0.99073555,0.105350366,DB0004610005483_,2.250463667,-0.456368181,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,insulin lispro,DB00046
,26614,DB00047,10005483,64,9221,81,8437,0.055023746,0.722962005,0.511878309,1.017388353,0.134370713,DB0004710005483_,2.007152787,-0.32439861,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,insulin glargine,DB00047
,26616,DB00471,10005483,44,14145,20,5445,0.576217278,0.846899952,0.488229318,1.51821287,0.725515959,DB0047110005483_,0.32087221,-0.166172711,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,montelukast,DB00471
,26617,DB00588,10005483,61,16463,42,8426,0.14473868,0.743387694,0.493165294,1.129917228,0.276647484,DB0058810005483_,1.285011203,-0.296537575,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,26618,DB00682,10005483,112,19347,93,16271,0.94405891,1.012828415,0.761787461,1.349205687,0.982775439,DB0068210005483_,0.017374629,0.012746828,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,warfarin,DB00682
,26620,DB00758,10005483,42,8258,60,10014,0.426920975,0.848857501,0.55758738,1.281795575,0.59559566,DB0075810005483_,0.518193265,-0.16386395,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,clopidogrel,DB00758
,26621,DB00761,10005483,121,15186,97,8528,0.010602494,0.700553133,0.531150463,0.925983666,0.037289965,DB0076110005483_,3.289031032,-0.355885066,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,potassium chloride,DB00761
,26623,DB00927,10005483,53,7444,58,4958,0.011104104,0.608665755,0.410588586,0.900628278,0.038691771,DB0092710005483_,3.252128337,-0.496486004,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,famotidine,DB00927
,26624,DB00996,10005483,130,38823,108,22317,0.005581404,0.691967156,0.531690727,0.90204613,0.022341766,DB0099610005483_,3.80129745,-0.368216787,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,gabapentin,DB00996
,26626,DB01076,10005483,148,25599,181,25402,0.060227357,0.811391875,0.648047346,1.014582926,0.143889845,DB0107610005483_,1.938707239,-0.209004142,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,atorvastatin,DB01076
,26627,DB01136,10005483,64,9820,109,11006,0.009124527,0.658084106,0.474975309,0.905362869,0.033085695,DB0113610005483_,3.40865426,-0.418422536,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,carvedilol,DB01136
,26630,DB00046,10007739,53,5406,28,4664,0.043375954,1.632971892,1.012524461,2.686088906,0.112411826,DB0004610007739_,2.185586134,0.490401601,NA,10007739,Cataract,10015919,Eye disorders,Eye,insulin lispro,DB00046
,26631,DB00047,10007739,58,9227,29,8489,0.006971807,1.839966292,1.157669558,2.983672691,0.026703671,DB0004710007739_,3.622954226,0.609747252,NA,10007739,Cataract,10015919,Eye disorders,Eye,insulin glargine,DB00047
,26632,DB00153,10007739,38,7385,15,3424,0.659243019,1.174532437,0.630194167,2.301809042,0.791820634,DB0015310007739_,0.233420385,0.160870143,NA,10007739,Cataract,10015919,Eye disorders,Eye,ergocalciferol,DB00153
,26633,DB00213,10007739,85,18810,37,13384,0.012710931,1.634583488,1.098039803,2.476089061,0.043099436,DB0021310007739_,3.14424537,0.491388025,NA,10007739,Cataract,10015919,Eye disorders,Eye,pantoprazole,DB00213
,26635,DB00471,10007739,55,14134,18,5447,0.602582065,1.177542807,0.680194512,2.132942998,0.746465093,DB0047110007739_,0.292406424,0.1634299,NA,10007739,Cataract,10015919,Eye disorders,Eye,montelukast,DB00471
,26636,DB00588,10007739,87,16437,30,8438,0.062856678,1.488704422,0.972046119,2.338084077,0.148698838,DB0058810007739_,1.905832237,0.397906226,NA,10007739,Cataract,10015919,Eye disorders,Eye,fluticasone propionate,DB00588
,26638,DB00682,10007739,69,19390,52,16312,0.58401502,1.116256061,0.767110326,1.633054169,0.73193319,DB0068210007739_,0.312066039,0.109980283,NA,10007739,Cataract,10015919,Eye disorders,Eye,warfarin,DB00682
,26640,DB00758,10007739,36,8264,21,10053,0.007345917,2.085331924,1.183918082,3.763002877,0.027822827,DB0075810007739_,3.581898476,0.734928039,NA,10007739,Cataract,10015919,Eye disorders,Eye,clopidogrel,DB00758
,26641,DB00761,10007739,99,15208,39,8586,0.061663796,1.43312188,0.979042209,2.134886545,0.146496103,DB0076110007739_,1.920756452,0.359855198,NA,10007739,Cataract,10015919,Eye disorders,Eye,potassium chloride,DB00761
,26645,DB01076,10007739,136,25611,86,25497,0.000951835,1.574333487,1.192341672,2.088390129,0.005289427,DB0107610007739_,5.242045396,0.453832,NA,10007739,Cataract,10015919,Eye disorders,Eye,atorvastatin,DB01076
,26646,DB01136,10007739,37,9847,40,11075,0.909151026,1.040368395,0.646423529,1.670487004,0.959169515,DB0113610007739_,0.041687457,0.039574876,NA,10007739,Cataract,10015919,Eye disorders,Eye,carvedilol,DB01136
,26649,DB00046,10007882,49,5410,51,4641,0.364809567,0.824232622,0.544206158,1.247208795,0.534400729,DB0004610007882_,0.626609293,-0.193302481,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,insulin lispro,DB00046
,26650,DB00047,10007882,69,9216,64,8454,1,0.988982619,0.692604371,1.413983765,1,DB0004710007882_,0,-0.011078522,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,26651,DB00153,10007882,47,7376,29,3410,0.218449984,0.749258326,0.460998388,1.23682458,0.37166842,DB0015310007882_,0.989753166,-0.288671461,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,ergocalciferol,DB00153
,26652,DB00213,10007882,125,18770,96,13325,0.583989376,0.924364079,0.702124889,1.220122802,0.7319185,DB0021310007882_,0.31208611,-0.07864926,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,26654,DB00471,10007882,72,14117,26,5439,0.822153858,1.066925765,0.672059633,1.743077804,0.905352611,DB0047110007882_,0.099430786,0.064781396,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,montelukast,DB00471
,26655,DB00588,10007882,103,16421,62,8406,0.322566852,0.850438646,0.613923185,1.18636538,0.49087681,DB0058810007882_,0.711562079,-0.162003009,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,26658,DB00758,10007882,44,8256,49,10025,0.677750775,1.090357798,0.70813538,1.67443465,0.804710413,DB0075810007882_,0.217272802,0.086505898,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,clopidogrel,DB00758
,26659,DB00761,10007882,165,15142,102,8523,0.480866252,0.910532908,0.706000883,1.17898257,0.64560336,DB0076110007882_,0.437569957,-0.093725238,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,26661,DB00927,10007882,64,7433,35,4981,0.35566541,1.225325869,0.797923623,1.909786402,0.525383011,DB0092710007882_,0.643627738,0.203206824,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,famotidine,DB00927
,26663,DB01076,10007882,146,25601,148,25435,0.906903399,0.980087351,0.773868065,1.241097461,0.95853111,DB0107610007882_,0.04235326,-0.020113577,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,26664,DB01136,10007882,62,9822,67,11048,0.859721064,1.040893775,0.723992743,1.494486187,0.933695617,DB0113610007882_,0.068604786,0.040079743,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,carvedilol,DB01136
,26689,DB00471,10016173,348,13841,94,5371,0.001807776,1.436647588,1.138126205,1.828094544,0.008952876,DB0047110016173_,4.715780503,0.362312335,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,26690,DB00627,10016173,41,1288,47,1552,0.828668069,1.051154238,0.669544412,1.644402656,0.909933794,DB0062710016173_,0.094383436,0.049888835,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,niacin,DB00627
,26691,DB00804,10016173,111,2889,14,885,0.000775393,2.428505291,1.379206905,4.609667721,0.004456367,DB0080410016173_,5.413421471,0.887275961,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,dicyclomine,DB00804
,26692,DB01020,10016173,73,1740,62,1816,0.254860338,1.228775409,0.85800141,1.764445498,0.415583857,DB0102010016173_,0.878070863,0.206018071,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,isosorbide mononitrate,DB01020
,26693,DB01076,10016173,883,24864,673,24910,1.26949923405138e-07,1.314451536,1.185805809,1.457566121,2.25846276595875e-06,DB0107610016173_,13.00082617,0.273419496,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,26696,DB00046,10018884,70,5389,56,4636,0.719666682,1.075356453,0.744158767,1.560146552,0.834536495,DB0004610018884_,0.180878804,0.072652191,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,insulin lispro,DB00046
,26697,DB00047,10018884,78,9207,81,8437,0.473119943,0.882435366,0.637278222,1.221266966,0.639117982,DB0004710018884_,0.447666206,-0.125069733,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,insulin glargine,DB00047
,26699,DB00471,10018884,94,14095,46,5419,0.185493279,0.785634305,0.545671119,1.145206709,0.330813233,DB0047110018884_,1.106201313,-0.241263856,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,montelukast,DB00471
,26700,DB00588,10018884,153,16371,78,8390,1,1.005271807,0.759409823,1.3397162,1,DB0058810018884_,0,0.00525796,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,26702,DB00706,10018884,10,1065,243,15682,0.150136298,0.605952191,0.286052804,1.138294141,0.284154133,DB0070610018884_,1.258238466,-0.500954189,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,tamsulosin,DB00706
,26703,DB00761,10018884,247,15060,139,8486,1,1.001290709,0.808677149,1.243817302,1,DB0076110018884_,0,0.001289877,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,26705,DB00927,10018884,102,7395,73,4943,0.697864925,0.933968775,0.683239656,1.28210795,0.818262916,DB0092710018884_,0.200571581,-0.068312273,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,famotidine,DB00927
,26706,DB01020,10018884,26,1787,38,1840,0.20698221,0.704572294,0.408895563,1.196735047,0.357600064,DB0102010018884_,1.028340056,-0.350164335,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,isosorbide mononitrate,DB01020
,26707,DB01136,10018884,157,9727,154,10961,0.229807953,1.148806235,0.91230515,1.446713483,0.385728099,DB0113610018884_,0.952622563,0.138723347,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,carvedilol,DB01136
,26709,DB13961,10018884,95,9362,73,6341,0.429992151,0.88144344,0.641742049,1.214911209,0.598495513,DB1396110018884_,0.513336252,-0.126194443,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,fish oil,DB13961
,26713,DB00126,10022595,24,10147,36,5909,0.000388723,0.38824861,0.221360988,0.669701834,0.002505233,DB0012610022595_,5.989373703,-0.946109397,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,ascorbic acid,DB00126
,26715,DB00213,10022595,54,18841,51,13370,0.164658482,0.751381457,0.502516589,1.124847649,0.303648101,DB0021310022595_,1.19188581,-0.285841824,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,pantoprazole,DB00213
,26720,DB00758,10022595,31,8269,64,10010,0.016994307,0.586375741,0.368632671,0.9149609,0.054376992,DB0075810022595_,2.911814157,-0.533794499,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,clopidogrel,DB00758
,26722,DB00996,10022595,56,38897,46,22379,0.080083677,0.70044347,0.465563598,1.058422628,0.178533518,DB0099610022595_,1.722978918,-0.356041616,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,gabapentin,DB00996
,26724,DB01136,10022595,45,9839,66,11049,0.182296654,0.765679152,0.511677677,1.136601695,0.326752876,DB0113610022595_,1.118551124,-0.266992059,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,carvedilol,DB01136
,26743,DB00996,10024453,49,38904,14,22411,0.018205859,2.016183335,1.095122541,3.955179076,0.057358699,DB0099610024453_,2.858430769,0.701206286,NA,10024453,Ligament sprain,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,26750,DB00046,10028596,40,5419,60,4632,0.006304268,0.569885318,0.371359559,0.866244913,0.024638717,DB0004610028596_,3.703436197,-0.562320135,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,insulin lispro,DB00046
,26751,DB00047,10028596,84,9201,122,8396,0.001201644,0.628307173,0.469317334,0.837784619,0.006413467,DB0004710028596_,5.049355319,-0.464726103,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,insulin glargine,DB00047
,26752,DB00126,10028596,56,10115,44,5901,0.146156096,0.742531397,0.490674157,1.129836453,0.278627284,DB0012610028596_,1.277880291,-0.297690124,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,ascorbic acid,DB00126
,26753,DB00153,10028596,29,7394,30,3409,0.002813126,0.445711138,0.257685051,0.769893278,0.012823969,DB0015310028596_,4.35643926,-0.808084209,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,ergocalciferol,DB00153
,26754,DB00243,10028596,22,1232,46,1580,0.063794121,0.613454802,0.349446156,1.04717349,0.150300583,DB0024310028596_,1.895118101,-0.48864869,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,ranolazine,DB00243
,26755,DB00471,10028596,64,14125,35,5430,0.11456842,0.702961815,0.457951736,1.095215618,0.232992721,DB0047110028596_,1.456748066,-0.352452705,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,montelukast,DB00471
,26757,DB00682,10028596,110,19349,142,16222,0.000743137,0.649472227,0.501177459,0.83974163,0.004301079,DB0068210028596_,5.448889367,-0.431595205,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,warfarin,DB00682
,26759,DB00758,10028596,254,8046,311,9763,0.931607774,0.991006781,0.834051136,1.176658759,0.972587046,DB0075810028596_,0.0277957,-0.009033902,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,26761,DB00996,10028596,163,38790,192,22233,1.99914811768295e-11,0.486587512,0.392216796,0.603121375,7.26297280902507e-10,DB0099610028596_,21.04306171,-0.720338513,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,gabapentin,DB00996
,26762,DB01020,10028596,47,1766,58,1820,0.374624775,0.835164911,0.552829384,1.256035715,0.544515164,DB0102010028596_,0.607859488,-0.180126075,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,isosorbide mononitrate,DB01020
,26764,DB13961,10028596,47,9410,68,6346,5.35137725540732e-05,0.466138989,0.313903786,0.687073302,0.000467701,DB1396110028596_,7.667682241,-0.76327143,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,fish oil,DB13961
,26770,DB00213,10029223,41,18854,21,13400,0.246791121,1.387590271,0.800799487,2.472813897,0.405875465,DB0021310029223_,0.901708903,0.327568625,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,26781,DB00996,10029223,156,38797,75,22350,0.217900396,1.198199158,0.903629569,1.600894795,0.371074465,DB0099610029223_,0.991352522,0.180819728,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,26783,DB01076,10029223,53,25694,41,25542,0.25623478,1.285026164,0.838404756,1.982098736,0.417059156,DB0107610029223_,0.874527206,0.250779079,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,26789,DB00047,10044390,30,9255,27,8491,1,1.019390077,0.585200896,1.783653784,1,DB0004710044390_,0,0.019204485,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,26792,DB00471,10044390,42,14147,17,5448,0.884480697,0.951421353,0.529593721,1.784246158,0.951918915,DB0047110044390_,0.049275421,-0.049798251,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,26798,DB01136,10044390,33,9851,34,11081,0.806561955,1.091769568,0.654882003,1.818278527,0.895441839,DB0113610044390_,0.110438008,0.087799837,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,26800,DB13961,10044390,30,9427,25,6389,0.491967125,0.813298237,0.461883397,1.443668224,0.65501299,DB1396110044390_,0.423100211,-0.206657401,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,26809,DB00588,10050296,40,16484,14,8454,0.2506816,1.465295973,0.779932773,2.917570079,0.410501565,DB0058810050296_,0.890375539,0.382057251,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,26817,DB00996,10050296,87,38866,36,22389,0.110671548,1.392128469,0.933564051,2.114821457,0.227088341,DB0099610050296_,1.48241617,0.330833848,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,26819,DB01076,10050296,27,25720,30,25553,0.69299382,0.894158642,0.51130197,1.556671194,0.815002163,DB0107610050296_,0.204564511,-0.111872067,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,26872,DB00588,10025082,84,16440,39,8429,0.634498295,1.104296248,0.746072322,1.660178199,0.772745868,DB0058810025082_,0.257805045,0.099208252,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,26873,DB01409,10025082,51,5980,23,3943,0.152201197,1.462015429,0.875755427,2.510731117,0.287008284,DB0140910025082_,1.248244201,0.379815915,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,26874,DB00588,10033664,42,16482,13,8455,0.117906123,1.657301592,0.872130099,3.366950042,0.238040051,DB0058810033664_,1.435316339,0.505190733,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,26876,DB00588,10061024,89,16435,50,8418,0.591087911,0.911721065,0.637038277,1.317644829,0.737527093,DB0058810061024_,0.304452455,-0.092421185,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,fluticasone propionate,DB00588
,26877,DB01409,10061024,41,5990,35,3931,0.289461078,0.768793971,0.476752999,1.245736494,0.454617856,DB0140910061024_,0.78829809,-0.262932264,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,tiotropium,DB01409
,26882,DB00820,10002034,392,11523,117,5699,9.49704355153818e-07,1.656997742,1.341066792,2.059992367,1.36858437364134e-05,DB0082010002034_,11.19914856,0.505007376,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,tadalafil,DB00820
,26883,DB06403,10002034,487,20984,94,6567,1.0633220376539e-05,1.621281017,1.295241545,2.047766576,0.000114476,DB0640310002034_,9.07514163,0.483216588,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ambrisentan,DB06403
,26884,DB06403,10003549,583,20888,186,6475,0.730905677,0.971624122,0.820383207,1.155001597,0.843476126,DB0640310003549_,0.17022368,-0.028786255,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,26885,DB00374,10066152,141,17575,41,5683,0.603640519,1.112026863,0.779335889,1.617651531,0.747265626,DB0037410066152_,0.291334567,0.106184353,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,treprostinil,DB00374
,26886,DB00820,10066152,209,11706,59,5757,0.00010417,1.74208627,1.296751753,2.371400599,0.000826541,DB0082010066152_,7.098260458,0.555083401,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,tadalafil,DB00820
,26887,DB06403,10066152,101,21370,29,6632,0.757441857,1.080841626,0.708385021,1.696377711,0.86438411,DB0640310066152_,0.145738037,0.077740021,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,ambrisentan,DB06403
,26888,DB00682,10062355,241,19218,113,16251,1.28013740127531e-07,1.803442826,1.434886473,2.277670039,2.27584792644719e-06,DB0068210062355_,12.99315786,0.589697519,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,26891,DB00005,10062132,190,127892,59,42360,0.714014878,1.066624537,0.792384228,1.454226522,0.830414853,DB0000510062132_,0.18582988,0.064499023,NA,10062132,Tooth extraction,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,26895,DB00381,10023547,122,29238,103,22784,0.59022764,0.923008693,0.703812003,1.212452222,0.736803453,DB0038110023547_,0.305434107,-0.080116626,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,amlodipine,DB00381
,26896,DB00480,10023547,1175,66253,1188,66474,0.868136667,0.992356034,0.914027178,1.077366603,0.941078569,DB0048010023547_,0.060728648,-0.00767333,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,lenalidomide,DB00480
,26897,DB11089,10023547,57,10118,52,8355,0.630099728,0.905161196,0.60984964,1.346006846,0.769081558,DB1108910023547_,0.262558258,-0.099642234,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,docusate,DB11089
,26898,DB05676,10046306,440,46689,193,25136,0.018990331,1.227330667,1.033226207,1.462327848,0.059335613,DB0567610046306_,2.824545599,0.204841622,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,apremilast,DB05676
,26899,DB08934,10033295,25,4464,55,6149,0.053515254,0.626147507,0.373250437,1.023680128,0.13159776,DB0893410033295_,2.028005283,-0.468169301,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,sofosbuvir,DB08934
,26901,DB08908,10006784,122,10551,12,3267,2.06204905068093e-05,3.147908524,1.735185325,6.267769384,0.000205112,DB0890810006784_,8.491952296,1.146738272,female,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,26902,DB00005,10005728,124,127958,51,42368,0.190225538,0.805040011,0.576491027,1.138635998,0.33683036,DB0000510005728_,1.088175858,-0.2168633,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,etanercept,DB00005
,26917,DB00175,10011224,173,7958,85,6021,0.001169048,1.539850303,1.17831518,2.025133751,0.006268551,DB0017510011224_,5.072210035,0.431685206,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,26918,DB00175,10037087,172,7959,81,6025,0.00040638,1.607412649,1.224522841,2.124875972,0.002597057,DB0017510037087_,5.953376471,0.474625836,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,pravastatin,DB00175
,26920,DB00153,10039101,55,7368,21,3418,0.536242613,1.214929365,0.721592373,2.118800112,0.692567663,DB0015310039101_,0.367349338,0.194685939,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,26921,DB00175,10039101,48,8083,20,6086,0.026703439,1.806971044,1.051034384,3.217925901,0.077357128,DB0017510039101_,2.55932255,0.591651987,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,26927,DB00126,10037153,104,10067,36,5909,0.006194459,1.695630902,1.148827909,2.554543485,0.024278141,DB0012610037153_,3.718178891,0.528054885,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,ascorbic acid,DB00126
,26928,DB01047,10037153,74,713,34,446,0.177462126,1.361117625,0.878438871,2.145102403,0.320623568,DB0104710037153_,1.13748753,0.308306146,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,fluocinonide,DB01047
,26929,DB01050,10037153,245,17863,78,9293,0.000117687,1.634051685,1.259889527,2.139100847,0.00091724,DB0105010037153_,6.994141761,0.491062627,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,26937,DB00158,10040642,37,16778,31,8073,0.026896507,0.574294967,0.346426252,0.958000273,0.077787829,DB0015810040642_,2.553770299,-0.554612135,NA,10040642,Sickle cell anaemia with crisis,10005329,Blood and lymphatic system disorders,Blood,folic acid,DB00158
,26938,DB00374,10040642,33,17683,19,5705,0.051423005,0.560371343,0.309143503,1.043927811,0.127707265,DB0037410040642_,2.05801463,-0.579155603,NA,10040642,Sickle cell anaemia with crisis,10005329,Blood and lymphatic system disorders,Blood,treprostinil,DB00374
,26943,DB01005,10040642,38,1057,30,837,1,1.003025933,0.599518762,1.691886343,1,DB0100510040642_,0,0.003021364,NA,10040642,Sickle cell anaemia with crisis,10005329,Blood and lymphatic system disorders,Blood,hydroxyurea,DB01005
,26946,DB00005,10006002,275,127807,56,42363,0.000572067,1.627647692,1.217117894,2.210734931,0.003453554,DB0000510006002_,5.668351299,0.487135839,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,26947,DB00051,10006002,48,25683,13,11407,0.126722238,1.639903701,0.874093718,3.30048123,0.251066107,DB0005110006002_,1.382039001,0.494637521,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,26949,DB08904,10019211,337,11273,60,3499,4.16986612470186e-05,1.743209705,1.317443253,2.340701282,0.000378078,DB0890410019211_,7.88040895,0.555728072,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,certolizumab pegol,DB08904
,26953,DB00051,10022000,164,25567,74,11346,0.888177402,0.983501893,0.742300361,1.313529094,0.953646495,DB0005110022000_,0.047462226,-0.016635716,NA,10022000,Influenza,10021881,Infections and infestations,Infec,adalimumab,DB00051
,26954,DB08904,10022000,140,11470,39,3520,0.657541237,1.10164005,0.765948124,1.617416683,0.790692277,DB0890410022000_,0.234846417,0.096800024,NA,10022000,Influenza,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,26955,DB08904,10025482,352,11258,71,3488,0.000881869,1.53594599,1.1836035,2.017099821,0.004967835,DB0890410025482_,5.304771201,0.429146471,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,26956,DB08904,10028813,354,11256,58,3501,2.12704377232998e-06,1.898204166,1.43067207,2.557918714,2.79774389615492e-05,DB0890410028813_,10.48411212,0.640908264,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,certolizumab pegol,DB08904
,26957,DB00051,10028836,131,25600,54,11366,0.690025462,1.077070001,0.778150795,1.508789875,0.813015717,DB0005110028836_,0.207004838,0.074244393,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,26959,DB08904,10047895,86,11524,33,3526,0.277620462,0.797389446,0.527046414,1.232373005,0.441241617,DB0890410047895_,0.81816267,-0.22641208,NA,10047895,Weight decreased,10022891,Investigations,Inv,certolizumab pegol,DB08904
,26963,DB00051,10060933,116,25615,22,11398,8.98574544382018e-05,2.346179882,1.477372198,3.890437253,0.000728918,DB0005110060933_,7.223948878,0.852788423,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,26964,DB08904,10060933,46,11564,10,3549,0.428859904,1.411695464,0.701806734,3.140630225,0.597365336,DB0890410060933_,0.515226399,0.344791439,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,26965,DB00005,10061156,287,127795,70,42349,0.019896923,1.35864654,1.042706121,1.791024347,0.061506601,DB0000510061156_,2.788610782,0.306489013,NA,10061156,Finger deformity,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,26968,DB00051,10061520,50,25681,19,11401,0.604137133,1.168267604,0.676339119,2.099343464,0.747563531,DB0005110061520_,0.290935985,0.155521971,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,26969,DB08904,10061520,48,11562,11,3548,0.443728665,1.339021315,0.684820753,2.862655756,0.611785869,DB0890410061520_,0.491372945,0.291938985,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,26975,DB00028,10018884,40,13418,28,5587,0.044488482,0.594847785,0.357555837,1.002266687,0.114566448,DB0002810018884_,2.166600289,-0.51944973,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,human immunoglobulin g,DB00028
,26976,DB00028,10018916,50,13408,48,5567,4.97306638825647e-05,0.432516483,0.28481956,0.657470879,0.000439607,DB0002810018916_,7.729630111,-0.838134843,NA,10018916,Haemolytic anaemia,10005329,Blood and lymphatic system disorders,Blood,human immunoglobulin g,DB00028
,26980,DB01202,10022437,104,6610,67,5651,0.075721845,1.327003037,0.964733331,1.835808728,0.171014194,DB0120210022437_,1.76600872,0.282923044,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,26981,DB01164,10030095,32,6492,40,7896,1,0.973011571,0.590879987,1.59051152,1,DB0116410030095_,0,-0.027359304,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,26983,DB01075,10001488,27,19921,33,11064,0.002721499,0.45441861,0.26268055,0.779784973,0.012483792,DB0107510001488_,4.38332411,-0.788736457,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,26984,DB01202,10001488,59,6655,70,5648,0.062293288,0.715345808,0.496239841,1.028157592,0.147731228,DB0120210001488_,1.912360683,-0.334989206,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,26985,DB00333,10001497,28,3043,32,3120,0.698965731,0.897158135,0.519084377,1.542332897,0.819004312,DB0033310001497_,0.19966593,-0.10852314,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,methadone,DB00333
,26986,DB01075,10001497,102,19846,87,11010,0.00373404,0.650402907,0.483324646,0.876908956,0.016129701,DB0107510001497_,4.127092933,-0.430163252,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,26991,DB00186,10016322,262,16639,108,9900,0.001364253,1.443376961,1.147566942,1.825813338,0.007113548,DB0018610016322_,4.945754102,0.36698548,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,26992,DB00333,10016322,30,3041,26,3126,0.59189727,1.186063583,0.67622464,2.093213086,0.738169039,DB0033310016322_,0.303582431,0.17063991,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,methadone,DB00333
,26993,DB01075,10016322,255,19693,83,11014,1.03302135392335e-05,1.718256829,1.334707166,2.231212183,0.000111649,DB0107510016322_,9.100153133,0.541310305,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,27001,DB00186,10022998,80,16821,55,9953,0.421875493,0.860665797,0.602421936,1.237418572,0.590908949,DB0018610022998_,0.526093336,-0.150049007,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,27003,DB01075,10022998,61,19887,31,11066,0.744313765,1.094945052,0.699002961,1.746941874,0.853962781,DB0107510022998_,0.157867668,0.090704182,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,27004,DB00186,10027175,170,16731,65,9943,0.002237332,1.554261977,1.159950772,2.1042416,0.01065657,DB0018610027175_,4.54157872,0.44100082,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,27005,DB00333,10027175,37,3034,14,3138,0.001028945,2.733091951,1.43968347,5.483666657,0.005639835,DB0033310027175_,5.177900491,1.005433551,female,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,methadone,DB00333
,27006,DB01202,10027175,78,6636,73,5645,0.566339265,0.908935152,0.650637315,1.270936803,0.717737161,DB0120210027175_,0.331651848,-0.095481528,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,27007,DB00186,10033864,33,16868,27,9981,0.22936364,0.723233593,0.421423282,1.251207402,0.3851362,DB0018610033864_,0.954158241,-0.324023021,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,27015,DB01075,10041466,58,19890,22,11075,0.130228641,1.467942821,0.884229476,2.52009307,0.256044568,DB0107510041466_,1.362403758,0.383861979,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,27016,DB01202,10041466,52,6662,27,5691,0.040965082,1.645149886,1.01302075,2.728051972,0.10759602,DB0120210041466_,2.229371621,0.497831496,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,27017,DB00186,10046571,366,16535,97,9911,4.43800794918535e-14,2.261569021,1.800667597,2.86307352,2.37340872724999e-12,DB0018610046571_,26.76669391,0.81605883,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,lorazepam,DB00186
,27018,DB01202,10046571,136,6578,54,5664,7.0825231758908e-07,2.168385204,1.567599717,3.036344398,1.05535216370913e-05,DB0120210046571_,11.45905095,0.773982745,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,levetiracetam,DB01202
,27019,DB00186,10048294,132,16769,120,9888,0.000804539,0.648663179,0.502065779,0.838702052,0.004596743,DB0018610048294_,5.382407297,-0.432841681,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,27020,DB00333,10048294,36,3035,47,3105,0.319958174,0.783656051,0.49168999,1.239713635,0.488122151,DB0033310048294_,0.717189594,-0.243785065,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,methadone,DB00333
,27021,DB01075,10048294,80,19868,80,11017,0.00024955,0.554550925,0.401241714,0.766354534,0.001732315,DB0107510048294_,6.358296583,-0.589596638,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,27022,DB00186,10049414,49,16852,41,9967,0.102390729,0.706878722,0.456923868,1.098531069,0.214577661,DB0018610049414_,1.539083549,-0.346896167,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,27030,DB00186,10061422,70,16831,44,9964,0.771247773,0.941825331,0.636339173,1.407351575,0.874746396,DB0018610061422_,0.133821268,-0.059935445,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,27032,DB01202,10061422,55,6659,38,5680,0.348043673,1.234555791,0.800501372,1.921808087,0.517575752,DB0120210061422_,0.658599383,0.210711222,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,27047,DB01164,10047899,62,6462,86,7850,0.455491701,0.875799151,0.620285679,1.230393235,0.622923907,DB0116410047899_,0.473330907,-0.132618494,NA,10047899,Weight increased,10022891,Investigations,Inv,calcium chloride,DB01164
,27052,DB00996,10028622,129,38824,118,22307,0.000331417,0.628163342,0.485259223,0.813675239,0.002190147,DB0099610028622_,6.12378672,-0.464955048,NA,10028622,Myoclonus,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,27053,DB00715,10013700,268,4575,42,2245,2.15957982787903e-14,3.130798391,2.244990665,4.462134501,1.21291785845727e-12,DB0071510013700_,27.43799221,1.141288049,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,paroxetine,DB00715
,27054,DB00158,10005557,76,16739,53,8051,0.047311462,0.689691352,0.478804291,0.99987793,0.12004844,DB0015810005557_,2.119859951,-0.371511097,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,folic acid,DB00158
,27055,DB00381,10005557,222,29138,186,22701,0.483267009,0.929880521,0.761204067,1.136969803,0.647467931,DB0038110005557_,0.434686014,-0.072699173,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,amlodipine,DB00381
,27058,DB00706,10005557,9,1066,124,15801,0.722782129,1.07580299,0.479259673,2.117266541,0.836857028,DB0070610005557_,0.178102038,0.07306735,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,tamsulosin,DB00706
,27059,DB00727,10005557,22,3821,35,4138,0.183419384,0.680753822,0.379688156,1.195830669,0.32816108,DB0072710005557_,1.114250695,-0.384554533,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,nitroglycerin,DB00727
,27061,DB01060,10005557,36,8551,33,5048,0.079750809,0.644056135,0.389763746,1.067342917,0.178017919,DB0106010005557_,1.725871065,-0.439969391,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,amoxicillin,DB01060
,27062,DB01076,10005557,271,25476,246,25337,0.309506739,1.095596861,0.91769063,1.308509724,0.476952843,DB0107610005557_,0.740337655,0.091299293,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,atorvastatin,DB01076
,27063,DB01132,10005557,53,1232,42,1488,0.046668418,1.523869689,0.989768196,2.359242661,0.118835493,DB0113210005557_,2.130015154,0.421252948,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,pioglitazone,DB01132
,27064,DB01136,10005557,96,9788,108,11007,1,0.999576259,0.75024191,1.330160615,1,DB0113610005557_,0,-0.000423831,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,carvedilol,DB01136
,27065,DB08907,10005557,106,4147,98,3812,1,0.994257354,0.74552913,1.327079283,1,DB0890710005557_,0,-0.005759199,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,canagliflozin,DB08907
,27068,DB00331,10005725,33,24913,46,20706,0.023695728,0.596261821,0.369203423,0.953299272,0.07052929,DB0033110005725_,2.651727196,-0.517075411,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,metformin,DB00331
,27069,DB00381,10005725,64,29296,57,22830,0.464755202,0.874993022,0.602423729,1.273667476,0.631746936,DB0038110005725_,0.459266383,-0.133539368,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,amlodipine,DB00381
,27070,DB00451,10005725,70,47201,36,15383,0.03136268,0.633707898,0.417950876,0.975806493,0.087703393,DB0045110005725_,2.433794696,-0.45616716,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,levothyroxine,DB00451
,27073,DB00682,10005725,41,19418,38,16326,0.734731358,0.907145608,0.568772945,1.45010704,0.846630548,DB0068210005725_,0.166490868,-0.097452304,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,warfarin,DB00682
,27078,DB01076,10005725,34,25713,57,25526,0.015641787,0.592162901,0.37529657,0.921596362,0.050944103,DB0107610005725_,2.97702627,-0.523973511,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,atorvastatin,DB01076
,27080,DB01136,10005725,35,9849,59,11056,0.062108906,0.665934509,0.424954938,1.02962707,0.147389541,DB0113610005725_,1.914676262,-0.406563948,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,carvedilol,DB01136
,27084,DB00451,10006093,115,47156,74,15345,9.15074796145382e-06,0.505685199,0.374136743,0.687125819,0.000100534,DB0045110006093_,9.205015348,-0.681840939,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,27090,DB01076,10006093,84,25663,112,25471,0.044890679,0.744395759,0.553880543,0.997219291,0.115364831,DB0107610006093_,2.159655727,-0.295182451,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,27095,DB00331,10007617,66,24880,94,20658,0.000793737,0.582995232,0.41870358,0.807664338,0.004545891,DB0033110007617_,5.393531509,-0.539576271,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,metformin,DB00331
,27096,DB00451,10007617,66,47205,55,15364,6.73927433732565e-07,0.390575412,0.268803103,0.569460479,1.01079501259118e-05,DB0045110007617_,11.5021883,-0.940134212,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,27099,DB00706,10007617,6,1069,44,15881,0.131991113,2.025700192,0.703836027,4.785324862,0.258629573,DB0070610007617_,1.352358463,0.705915415,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,tamsulosin,DB00706
,27103,DB01076,10007617,63,25684,85,25498,0.070045592,0.735816159,0.522340317,1.031840669,0.161342751,DB0107610007617_,1.824224288,-0.306774975,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,27107,DB00331,10010305,225,24721,239,20513,0.008638133,0.781182548,0.647585282,0.942029335,0.031671546,DB0033110010305_,3.452336595,-0.24694642,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,metformin,DB00331
,27110,DB01076,10010305,258,25489,318,25265,0.010527317,0.804195915,0.679090013,0.951665892,0.037087592,DB0107610010305_,3.294472818,-0.217912364,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,27114,DB00484,10012735,85,2422,40,1740,0.033721194,1.52648472,1.030797987,2.294150204,0.092817592,DB0048410012735_,2.377119085,0.422967523,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,brimonidine,DB00484
,27116,DB00706,10012735,53,1022,862,15063,0.530280002,0.906207621,0.668472243,1.206255148,0.687349156,DB0070610012735_,0.374912883,-0.098486837,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,tamsulosin,DB00706
,27117,DB00727,10012735,195,3648,160,4013,0.007693516,1.340634984,1.076743688,1.671166418,0.028872655,DB0072710012735_,3.544860329,0.29314337,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,nitroglycerin,DB00727
,27118,DB00905,10012735,44,2674,31,894,0.002827892,0.474634377,0.291037968,0.782657789,0.012877881,DB0090510012735_,4.352244082,-0.745210505,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,bimatoprost,DB00905
,27119,DB01132,10012735,79,1206,80,1450,0.325399834,1.187216608,0.85042392,1.657113917,0.493815689,DB0113210012735_,0.705592931,0.171611582,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pioglitazone,DB01132
,27120,DB08907,10012735,109,4144,89,3821,0.428523407,1.129242352,0.842516492,1.516868769,0.597086472,DB0890710012735_,0.515693331,0.121546923,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,canagliflozin,DB08907
,27122,DB00158,10021097,166,16649,123,7981,0.000385281,0.646952853,0.508473431,0.824961528,0.002485792,DB0015810021097_,5.997163851,-0.435481857,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,folic acid,DB00158
,27123,DB00484,10021097,35,2472,29,1751,0.6095169,0.85491984,0.505541147,1.455854306,0.751919637,DB0048410021097_,0.285125826,-0.156747569,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,brimonidine,DB00484
,27125,DB00727,10021097,93,3750,158,4015,0.00050551,0.630241147,0.480522029,0.822753274,0.003116168,DB0072710021097_,5.77115119,-0.46165276,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,nitroglycerin,DB00727
,27128,DB08907,10021097,32,4221,51,3859,0.014821706,0.573683717,0.355969703,0.912175905,0.048851228,DB0890710021097_,3.018975755,-0.55567705,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,canagliflozin,DB08907
,27130,DB00331,10022595,15,24931,46,20706,3.4813213232509e-06,0.270833041,0.14040625,0.494139958,4.30315217407242e-05,DB0033110022595_,10.05357765,-1.306252734,male,10022595,International normalised ratio increased,10022891,Investigations,Inv,metformin,DB00331
,27140,DB00451,10027417,72,47199,34,15385,0.089488067,0.690273591,0.452852254,1.071138158,0.194444395,DB0045110027417_,1.637609041,-0.370667251,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,27143,DB00682,10027417,32,19427,27,16337,1,0.996673169,0.578181184,1.730085531,1,DB0068210027417_,0,-0.003332378,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,27148,DB01076,10027417,42,25705,35,25548,0.494227608,1.192665121,0.743098255,1.924836137,0.656804057,DB0107610027417_,0.420369543,0.1761904,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,27150,DB01136,10027417,45,9839,17,11098,5.80598947962244e-05,2.985630816,1.674348478,5.568493553,0.000501596,DB0113610027417_,7.597716523,1.093811053,female,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,carvedilol,DB01136
,27151,DB08907,10027417,46,4207,49,3861,0.472074414,0.861583811,0.561991613,1.318874652,0.63814837,DB0890710027417_,0.449184468,-0.148982943,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,canagliflozin,DB08907
,27153,DB00158,10035664,582,16233,371,7733,2.26790236818689e-05,0.747287296,0.653057449,0.856017275,0.000222515,DB0015810035664_,8.410515284,-0.291305568,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,folic acid,DB00158
,27154,DB00484,10035664,56,2451,53,1727,0.139784172,0.744556627,0.499477932,1.111097809,0.26950979,DB0048410035664_,1.311150564,-0.294966369,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,brimonidine,DB00484
,27156,DB00706,10035664,47,1028,732,15193,0.821009077,0.948937343,0.686340201,1.284944192,0.904700649,DB0070610035664_,0.100151165,-0.052412506,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,tamsulosin,DB00706
,27157,DB00905,10035664,28,2690,30,895,2.11824587987306e-05,0.310654308,0.177761583,0.541331766,0.000209789,DB0090510035664_,8.469406636,-1.169074535,male,10035664,Pneumonia,10021881,Infections and infestations,Infec,bimatoprost,DB00905
,27158,DB01132,10035664,33,1252,38,1492,0.904437571,1.03489256,0.62493905,1.70588359,0.957532637,DB0113210035664_,0.043395473,0.034297614,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pioglitazone,DB01132
,27161,DB00158,10047700,484,16331,139,7965,1.57212036428923e-08,1.698224478,1.400614615,2.069793608,3.37332112451774e-07,DB0015810047700_,14.90219789,0.529583281,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,27163,DB00706,10047700,32,1043,260,15665,0.002240719,1.848332174,1.231778409,2.691511334,0.010668925,DB0070610047700_,4.540419981,0.614283705,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,tamsulosin,DB00706
,27165,DB01060,10047700,288,8299,122,4959,0.001528943,1.410556427,1.13399961,1.763039266,0.007813411,DB0106010047700_,4.851913708,0.343984256,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,27166,DB01132,10047700,48,1237,40,1490,0.102637751,1.44522635,0.923330071,2.272872143,0.214975361,DB0113210047700_,1.537231858,0.368265953,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pioglitazone,DB01132
,27167,DB08907,10047700,109,4144,70,3840,0.018869687,1.442843221,1.055322195,1.983554649,0.059028827,DB0890710047700_,2.829729368,0.366615626,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,canagliflozin,DB08907
,27175,DB00682,10060320,89,19370,215,16149,8.72293843079942e-19,0.345127771,0.26623047,0.444263757,8.08756390312391e-17,DB0068210060320_,37.05361902,-1.06384058,male,10060320,Anticoagulation drug level above therapeutic,10022891,Investigations,Inv,warfarin,DB00682
,27187,DB00381,10061105,51,29309,39,22848,1,1.019420157,0.65849899,1.589199957,1,DB0038110061105_,0,0.019233992,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,amlodipine,DB00381
,27188,DB00451,10061105,45,47226,20,15399,0.250142838,0.733662462,0.424275052,1.312046667,0.409836347,DB0045110061105_,0.891997353,-0.309706216,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,levothyroxine,DB00451
,27195,DB01076,10061105,35,25712,35,25548,1,0.993621461,0.603706111,1.635456856,1,DB0107610061105_,0,-0.006398969,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,atorvastatin,DB01076
,27197,DB01136,10061105,20,9864,33,11082,0.214693281,0.68091077,0.370001255,1.223247902,0.36707405,DB0113610061105_,1.002191681,-0.384324009,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,carvedilol,DB01136
,27200,DB00158,10011224,353,16462,113,7991,9.50614224270022e-05,1.516379963,1.221332409,1.894534573,0.000763075,DB0015810011224_,7.178154075,0.416325891,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,27201,DB00563,10011224,746,45900,228,15120,0.349540485,1.077810479,0.926893443,1.257155744,0.519165489,DB0056310011224_,0.655532586,0.074931649,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,27202,DB00715,10011224,70,4773,28,2259,0.513729142,1.183175792,0.750918964,1.910955906,0.673695227,DB0071510011224_,0.394977456,0.168202173,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,paroxetine,DB00715
,27203,DB00005,10012442,73,128009,37,42382,0.036345081,0.653226029,0.434013954,0.998328359,0.098244598,DB0000510012442_,2.320295017,-0.425832071,NA,10012442,Dermatitis contact,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,27209,DB00158,10020751,152,16663,36,8068,5.93769257082157e-05,2.044291702,1.412173585,3.030773127,0.000511126,DB0015810020751_,7.578894903,0.715051373,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,folic acid,DB00158
,27211,DB00158,10037087,337,16478,100,8004,8.86958454282563e-06,1.636909186,1.303540223,2.070758794,9.77923782332935e-05,DB0015810037087_,9.232663916,0.492809821,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,27212,DB00715,10037087,89,4754,29,2258,0.090498932,1.457590084,0.945852777,2.306694714,0.196041242,DB0071510037087_,1.629430226,0.376784445,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,paroxetine,DB00715
,27215,DB00338,10037867,58,33616,38,22234,1,1.009522459,0.658988919,1.562805804,1,DB0033810037867_,0,0.009477406,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,27216,DB00563,10037867,51,46595,13,15335,0.470728608,1.291117794,0.691904418,2.588540349,0.636965043,DB0056310037867_,0.451040502,0.25550835,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,27219,DB00338,10041232,61,33613,19,22253,0.002867231,2.12544759,1.252210276,3.769033784,0.013031065,DB0033810041232_,4.340419168,0.753982411,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,27220,DB00563,10041232,53,46593,7,15341,0.016338401,2.493027762,1.129109154,6.501512536,0.052680795,DB0056310041232_,2.94350432,0.91349794,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,27222,DB00005,10052140,159,127923,25,42394,0.000222857,2.10757782,1.376585376,3.355313494,0.001578073,DB0000510052140_,6.451550722,0.745539336,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,etanercept,DB00005
,27225,DB00338,10052140,50,33624,16,22256,0.011282959,2.068430517,1.15812083,3.892736453,0.039179944,DB0033810052140_,3.239590305,0.726790115,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,omeprazole,DB00338
,27230,DB00927,10003239,164,7333,64,4952,0.000165294,1.730389843,1.285575559,2.353242127,0.001226813,DB0092710003239_,6.703335408,0.548346726,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,famotidine,DB00927
,27231,DB01075,10003239,366,19582,153,10944,0.00265087,1.336918008,1.102388641,1.627683016,0.012219941,DB0107510003239_,4.404686128,0.290366971,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,27232,DB01229,10003239,124,5617,26,2683,6.11149343997155e-05,2.277869661,1.47897535,3.632735899,0.000523771,DB0122910003239_,7.554455747,0.823240647,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,paclitaxel,DB01229
,27233,DB00904,10033371,1029,22040,361,14095,1.14716842284585e-23,1.822862774,1.612245073,2.064648977,1.62114634379049e-21,DB0090410033371_,47.87115343,0.600408218,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,27234,DB00927,10033371,297,7200,99,4917,2.07248378969429e-10,2.048629707,1.621608482,2.606396682,6.43155093413393e-09,DB0092710033371_,18.86205012,0.717171134,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,27235,DB00051,10009887,80,25651,39,11381,0.619988504,0.910132013,0.612833873,1.371970985,0.760572087,DB0005110009887_,0.273684383,-0.094165621,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,27236,DB00115,10009887,52,18373,18,10454,0.080637573,1.64371362,0.945216051,2.987315515,0.179433533,DB0011510009887_,1.717950427,0.496958084,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,27248,DB00051,10025197,90,25641,32,11388,0.325667971,1.249090758,0.825544728,1.934195286,0.49415128,DB0005110025197_,0.704913574,0.222415893,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,adalimumab,DB00051
,27249,DB00115,10025197,37,18388,26,10446,0.43198476,0.808450998,0.476229235,1.391299031,0.600431933,DB0011510025197_,0.510105994,-0.212635211,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,cyanocobalamin,DB00115
,27255,DB01175,10047895,174,10550,87,4805,0.501033325,0.910909338,0.698562524,1.195054219,0.662507782,DB0117510047895_,0.411722975,-0.093311906,NA,10047895,Weight decreased,10022891,Investigations,Inv,escitalopram,DB01175
,27257,DB00051,10056342,56,25675,23,11397,0.808125338,1.080783999,0.653995153,1.8412729,0.896477889,DB0005110056342_,0.10928165,0.077686703,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,27258,DB00115,10056342,34,18391,16,10456,0.658981746,1.208100701,0.64854567,2.345174829,0.791741981,DB0011510056342_,0.233519722,0.189049458,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,27271,DB00472,10000081,148,10611,47,4265,0.175312319,1.265647336,0.904036832,1.800528156,0.317831796,DB0047210000081_,1.146232979,0.23558372,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,27272,DB00959,10028813,471,7607,181,4821,1.02463807123088e-08,1.649110261,1.38092626,1.975987061,2.29996684050415e-07,DB0095910028813_,15.28520095,0.500235907,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,27277,DB00761,10000081,316,14991,108,8517,3.15119849444385e-06,1.662304525,1.329726367,2.091398781,3.95083484027935e-05,DB0076110000081_,10.13899856,0.508204907,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,27278,DB05351,10000081,58,2665,22,1109,0.804352334,1.097055665,0.657447171,1.892189154,0.894291439,DB0535110000081_,0.111723563,0.092629923,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,dexlansoprazole,DB05351
,27279,DB00811,10008531,50,2748,60,4096,0.281306082,1.24206466,0.833217261,1.844686555,0.445282007,DB0081110008531_,0.809047473,0.216775043,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,27281,DB05351,10028813,201,2522,49,1082,0.000409349,1.759645572,1.270574213,2.476832609,0.00261317,DB0535110028813_,5.947191116,0.565112409,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dexlansoprazole,DB05351
,27283,DB08934,10037660,58,4431,48,6156,0.009805995,1.67861859,1.122974523,2.519349032,0.035022837,DB0893410037660_,3.351754931,0.517971187,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,27284,DB05351,10047700,87,2636,25,1106,0.113768831,1.460017371,0.920816895,2.391632782,0.231806032,DB0535110047700_,1.461854327,0.378448333,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dexlansoprazole,DB05351
,27285,DB08934,10047700,156,4333,135,6069,6.58230475627248e-05,1.61841141,1.272746468,2.060213299,0.000556858,DB0893410047700_,7.49319971,0.481445057,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sofosbuvir,DB08934
,27289,DB00916,10000081,182,5141,58,2373,0.016063518,1.448352207,1.067570596,1.989741699,0.051982547,DB0091610000081_,2.956847255,0.370426501,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,metronidazole,DB00916
,27293,DB00727,10002383,28,3815,44,4129,0.125403242,0.688774502,0.412015459,1.133912379,0.249223061,DB0072710002383_,1.389406956,-0.372841345,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,nitroglycerin,DB00727
,27294,DB00758,10002383,38,8262,62,10012,0.159063581,0.742737074,0.481930275,1.131351866,0.296250706,DB0075810002383_,1.216549202,-0.297413167,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,27303,DB00727,10008479,180,3663,195,3978,1,1.002456756,0.809870329,1.240314971,1,DB0072710008479_,0,0.002453744,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,27304,DB00758,10008479,198,8102,255,9819,0.534710333,0.941010778,0.775757075,1.140233391,0.691302007,DB0075810008479_,0.369178493,-0.060800685,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,27305,DB01068,10008479,155,13608,69,6771,0.475989095,1.117729495,0.835089919,1.509074539,0.641432955,DB0106810008479_,0.444050613,0.111299391,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,27308,DB00254,10055798,44,5891,11,3377,0.011037477,2.292809864,1.163226841,4.930221944,0.038508108,DB0025410055798_,3.25688645,0.82977808,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,doxycycline,DB00254
,27311,DB00557,10007882,42,5945,20,3047,0.893076307,1.076305854,0.616709838,1.93879854,0.955451035,DB0055710007882_,0.045571762,0.073534672,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,hydroxyzine,DB00557
,27313,DB01075,10007882,125,19823,62,11035,0.491415251,1.122343708,0.820527469,1.548815526,0.654564566,DB0107510007882_,0.423785049,0.115419095,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,27314,DB01098,10007882,52,8097,31,7178,0.097548261,1.486992157,0.93416051,2.403153193,0.207196448,DB0109810007882_,1.574087912,0.396755393,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,rosuvastatin,DB01098
,27317,DB01409,10007882,32,5999,25,3941,0.587402467,0.840906651,0.482012164,1.482525798,0.734462651,DB0140910007882_,0.308616135,-0.173274623,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,tiotropium,DB01409
,27320,DB00374,10010774,281,17435,77,5647,0.214977492,1.18197159,0.913776313,1.544253194,0.367380697,DB0037410010774_,1.001356647,0.167183883,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,27324,DB01234,10017626,32,31593,43,32845,0.299032922,0.773682263,0.473683381,1.251848296,0.465010965,DB0123410017626_,0.765694293,-0.256594003,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,dexamethasone,DB01234
,27327,DB01175,10022998,42,10682,35,4857,0.009422672,0.545621462,0.339637167,0.881535006,0.033939697,DB0117510022998_,3.383169958,-0.605829836,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,27330,DB00422,10020772,47,3388,42,2907,0.914830509,0.96016422,0.617743846,1.496730345,0.961903265,DB0042210020772_,0.03884139,-0.040650946,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,methylphenidate,DB00422
,27331,DB00422,10033557,35,3400,24,2925,0.432691507,1.254550106,0.723431158,2.209903236,0.601093824,DB0042210033557_,0.509004243,0.226777027,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,methylphenidate,DB00422
,27336,DB08908,10037377,55,10618,23,3256,0.227636784,0.733309133,0.442446269,1.252359887,0.382922503,DB0890810037377_,0.959922652,-0.310187929,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dimethyl fumarate,DB08908
,27338,DB01261,10007559,41,3740,48,3255,0.166469492,0.74343504,0.476472698,1.155255135,0.306096579,DB0126110007559_,1.183854611,-0.296473887,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,sitagliptin,DB01261
,27349,DB00115,10005734,73,18352,28,10444,0.078329856,1.483688111,0.947004887,2.384716304,0.175591682,DB0011510005734_,1.739593966,0.394530955,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,27350,DB00126,10005734,37,10134,35,5910,0.049365666,0.616557959,0.377311799,1.009289109,0.123832279,DB0012610005734_,2.088827219,-0.483602948,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,ascorbic acid,DB00126
,27356,DB00115,10035598,88,18337,62,10410,0.20182409,0.805793028,0.575066699,1.134949214,0.351238558,DB0011510035598_,1.046289635,-0.215928359,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,27357,DB00126,10035598,58,10113,46,5899,0.126590616,0.735511017,0.490165335,1.109235052,0.250917931,DB0012610035598_,1.382629363,-0.307189761,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,27358,DB00169,10035598,181,38510,116,18059,0.010405687,0.731696117,0.575952503,0.932639261,0.036734907,DB0016910035598_,3.304027832,-0.312389992,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,27360,DB00115,10040047,158,18267,154,10318,1.94613911534688e-06,0.57955672,0.46056641,0.729306026,2.58550753838225e-05,DB0011510040047_,10.56300364,-0.545491744,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,27361,DB00126,10040047,114,10057,116,5829,2.48725526001367e-05,0.569651506,0.435058773,0.745701078,0.000240491,DB0012610040047_,8.332827491,-0.562730498,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,27362,DB00698,10040047,42,3106,13,416,0.018417388,0.432847715,0.22563352,0.886490141,0.057899896,DB0069810040047_,2.849039682,-0.837369311,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,nitrofurantoin,DB00698
,27393,DB00641,10046735,114,14010,67,12408,0.008731863,1.5069047,1.103662393,2.071356603,0.031953092,DB0064110046735_,3.443486329,0.410057679,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,27394,DB00722,10046735,216,25187,188,25844,0.109827898,1.178900804,0.964269382,1.442387934,0.225815575,DB0072210046735_,1.488036652,0.164582482,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,27395,DB00999,10046735,220,21210,86,12153,0.002312826,1.465758102,1.13615703,1.905224018,0.010949683,DB0099910046735_,4.514444728,0.382372585,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,27397,DB00207,10035664,427,8653,360,5095,1.45410427093667e-06,0.698439363,0.602945605,0.809317441,2.00372900453842e-05,DB0020710035664_,10.81791552,-0.358906915,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,azithromycin,DB00207
,27399,DB01222,10035664,541,8733,364,5041,0.029987198,0.857939451,0.746349831,0.987047773,0.084685845,DB0122210035664_,2.46880681,-0.153221752,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,budesonide,DB01222
,27400,DB01222,10047895,150,9124,107,5298,0.117234076,0.814040591,0.629466777,1.055695588,0.236992708,DB0122210047895_,1.439725905,-0.205745049,NA,10047895,Weight decreased,10022891,Investigations,Inv,budesonide,DB01222
,27401,DB01409,10047895,91,5940,90,3876,0.005749885,0.659822809,0.48610906,0.895670848,0.022887217,DB0140910047895_,3.777176721,-0.415783951,NA,10047895,Weight decreased,10022891,Investigations,Inv,tiotropium,DB01409
,27402,DB00682,10029331,180,19279,155,16209,0.825847362,0.976360081,0.782448734,1.219492984,0.908031369,DB0068210029331_,0.096476354,-0.023923825,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,27404,DB01041,10030124,48,2997,35,3083,0.150369062,1.410696738,0.890823364,2.254039214,0.284451299,DB0104110030124_,1.257193221,0.344083723,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,thalidomide,DB01041
,27411,DB00273,10012735,301,8180,39,2154,1.11386604296065e-05,2.032147299,1.446883677,2.924738686,0.000119113,DB0027310012735_,9.035438156,0.709093017,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,topiramate,DB00273
,27412,DB01255,10012735,46,2087,31,1547,0.727752453,1.099927932,0.679038908,1.803385075,0.841111278,DB0125510012735_,0.173031312,0.095244661,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lisdexamfetamine,DB01255
,27413,DB00273,10013781,43,8438,9,2184,0.730455993,1.236602138,0.593411718,2.889528341,0.843179297,DB0027310013781_,0.170575654,0.212367407,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,topiramate,DB00273
,27414,DB00425,10013781,78,12617,26,7458,0.010696324,1.773273949,1.123653468,2.883312269,0.037567195,DB0042510013781_,3.281624092,0.572827527,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,27417,DB00715,10000081,60,4783,24,2263,0.557142476,1.182793102,0.723427109,1.991412925,0.710345847,DB0071510000081_,0.34200332,0.167878677,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,paroxetine,DB00715
,27421,DB01234,10041569,89,31536,80,32808,0.355933689,1.157368769,0.845690525,1.586131441,0.525628851,DB0123410041569_,0.643159922,0.146149126,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,27423,DB00264,10015090,221,29386,159,24733,0.13431353,1.169849587,0.949124514,1.444621327,0.261736378,DB0026410015090_,1.340417474,0.156875182,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,27425,DB00390,10015090,71,4074,37,3264,0.04002741,1.53730708,1.016185282,2.360055002,0.105735438,DB0039010015090_,2.246815173,0.430032237,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,27426,DB00887,10015090,39,2302,13,1802,0.007017527,2.347912822,1.222463549,4.808600484,0.026845538,DB0088710015090_,3.617655671,0.853526773,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bumetanide,DB00887
,27428,DB14500,10015090,69,7740,23,4050,0.06134929,1.569712194,0.965154534,2.641692523,0.145920378,DB1450010015090_,1.92469416,0.450892287,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,27429,DB14726,10015090,34,1983,47,2801,0.910115405,1.021816374,0.63476243,1.629507325,0.959542868,DB1472610015090_,0.041298287,0.021581803,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dabigatran,DB14726
,27433,DB00472,10002368,32,10727,20,4292,0.124708334,0.640199696,0.354641228,1.182546667,0.248142208,DB0047210002368_,1.393753278,-0.445975127,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,27438,DB00472,10003239,212,10547,55,4257,0.0032283,1.555768087,1.14884712,2.137538266,0.014360443,DB0047210003239_,4.243277885,0.44196937,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fluoxetine,DB00472
,27439,DB01175,10003239,246,10478,61,4831,6.87566958768316e-06,1.859296519,1.396427475,2.508569618,7.82198550583216e-05,DB0117510003239_,9.455987042,0.620198201,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,27442,DB00472,10003549,194,10565,91,4221,0.209292908,0.851764854,0.658807626,1.107935118,0.360349952,DB0047210003549_,1.020679631,-0.160444783,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,27452,DB00472,10013573,330,10429,110,4202,0.096878945,1.20871644,0.968178676,1.518464361,0.206098909,DB0047210013573_,1.579399084,0.189559004,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,27455,DB00472,10013968,326,10433,124,4188,0.634039484,1.055338292,0.852809894,1.312653481,0.772401818,DB0047210013968_,0.258250375,0.053861371,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,27456,DB00191,10016256,61,1065,11,226,0.749784966,1.176646671,0.601449469,2.520337866,0.858273177,DB0019110016256_,0.152832842,0.162668589,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,phentermine,DB00191
,27481,DB01175,10028391,43,10681,20,4872,1,0.980695542,0.563835501,1.761683431,1,DB0117510028391_,0,-0.019493223,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,27487,DB01175,10029410,49,10675,9,4883,0.009939654,2.490298285,1.209290762,5.771063577,0.035389613,DB0117510029410_,3.34133693,0.912402497,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,escitalopram,DB01175
,27495,DB00472,10042458,206,10553,78,4234,0.691375214,1.059609192,0.810594083,1.39683287,0.813919941,DB0047210042458_,0.20589327,0.057900153,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,27497,DB01175,10042458,152,10572,75,4817,0.565029115,0.923432382,0.694229285,1.23719603,0.716681479,DB0117510042458_,0.333123778,-0.079657701,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,27500,DB01175,10046571,234,10490,56,4836,4.97182717474568e-06,1.926294296,1.430531932,2.632418251,5.89199627088324e-05,DB0117510046571_,9.739330599,0.655598103,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,escitalopram,DB01175
,27515,DB01175,10051055,52,10672,34,4858,0.103489729,0.696210615,0.442676387,1.107928326,0.216260088,DB0117510051055_,1.531273485,-0.362103057,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,escitalopram,DB01175
,27549,DB00472,10068319,58,10701,13,4299,0.064424947,1.792313691,0.969349022,3.569594835,0.151406833,DB0047210068319_,1.887784809,0.58350735,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,27551,DB01175,10068319,63,10661,14,4878,0.01321461,2.058918456,1.139742827,3.983384714,0.044457447,DB0117510068319_,3.11322279,0.722180824,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,27562,DB00203,10053483,209,13669,63,8875,2.06316457663819e-08,2.153884659,1.615717208,2.905832843,4.31083313966095e-07,DB0020310053483_,14.65696446,0.76727303,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,27563,DB00374,10053483,723,16993,195,5529,0.022963582,1.206352881,1.025359823,1.424592205,0.068823203,DB0037410053483_,2.676214339,0.18760166,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,27564,DB06403,10053483,232,21239,51,6610,0.024385444,1.41570776,1.040185548,1.959330207,0.072140842,DB0640310053483_,2.629134929,0.34762959,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,27565,DB00203,10062546,42,13836,17,8921,0.110239829,1.592922364,0.88691568,2.986640402,0.226405743,DB0020310062546_,1.485426565,0.465570294,NA,10062546,Thrombosis in device,10077536,Product issues,Prod,sildenafil,DB00203
,27566,DB00374,10062546,49,17667,9,5715,0.126972519,1.761084797,0.855399355,4.080578926,0.251419841,DB0037410062546_,1.380631066,0.565929981,NA,10062546,Thrombosis in device,10077536,Product issues,Prod,treprostinil,DB00374
,27568,DB00203,10065464,48,13830,16,8922,0.020713978,1.935301863,1.079028902,3.653490764,0.063535434,DB0020310065464_,2.756157517,0.660263316,NA,10065464,Infusion site haemorrhage,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,27569,DB00374,10065464,143,17573,36,5688,0.190797789,1.285698753,0.8855797,1.91073762,0.337559391,DB0037410065464_,1.086013811,0.251302348,NA,10065464,Infusion site haemorrhage,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,27570,DB06403,10065464,46,21425,10,6651,0.348386104,1.427948793,0.710317468,3.175485527,0.517963107,DB0640310065464_,0.657851261,0.356239004,NA,10065464,Infusion site haemorrhage,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,27572,DB00374,10065600,71,17645,13,5711,0.056665261,1.767576587,0.969531918,3.484038155,0.13722689,DB0037410065600_,1.986119592,0.569609449,NA,10065600,Injection site discharge,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,27578,DB01109,10007617,25,4387,40,4230,0.047029644,0.602671798,0.349746826,1.020104786,0.119506399,DB0110910007617_,2.124385359,-0.506382512,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,heparin,DB01109
,27580,DB01109,10014625,30,4382,24,4246,0.498406223,1.211176664,0.683286225,2.168791152,0.660264011,DB0110910014625_,0.415115508,0.191592337,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,heparin,DB01109
,27582,DB01109,10021097,148,4264,193,4077,0.00567252,0.733239126,0.585240223,0.917166499,0.02262416,DB0110910021097_,3.788736899,-0.310283401,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,heparin,DB01109
,27583,DB01225,10021097,148,4896,148,4492,0.478667251,0.917497725,0.72287993,1.164500083,0.643915824,DB0122510021097_,0.44018727,-0.086105178,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,enoxaparin,DB01225
,27586,DB01109,10035598,42,4370,41,4229,1,0.991338198,0.627719242,1.566684933,1,DB0110910035598_,0,-0.008699534,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,heparin,DB01109
,27587,DB01225,10035598,54,4990,45,4595,0.686140822,1.104978906,0.728543896,1.683030543,0.810607735,DB0122510035598_,0.209971022,0.099826245,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enoxaparin,DB01225
,27590,DB01109,10038435,36,4376,49,4221,0.127306106,0.708702315,0.446722161,1.114770585,0.251881144,DB0110910038435_,1.378797952,-0.344319707,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,heparin,DB01109
,27591,DB01225,10038435,32,5012,46,4594,0.05326319,0.637669763,0.392254274,1.025198547,0.131112844,DB0122510038435_,2.031696926,-0.449934742,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,enoxaparin,DB01225
,27592,DB01109,10043554,77,4335,204,4066,6.16377508748779e-16,0.354068763,0.267847734,0.464112166,4.20817735518485e-14,DB0110910043554_,30.79916168,-1.038264139,male,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,heparin,DB01109
,27593,DB01225,10043554,86,4958,91,4549,0.362741302,0.867108379,0.636294797,1.180829759,0.532273931,DB0122510043554_,0.630597014,-0.142591305,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,enoxaparin,DB01225
,27594,DB01109,10045555,27,4385,46,4224,0.018666401,0.565446414,0.337348449,0.93083958,0.058515673,DB0110910045555_,2.838460646,-0.570139746,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,heparin,DB01109
,27595,DB01225,10045555,21,5023,31,4609,0.096174751,0.621621551,0.338968594,1.118760337,0.204998163,DB0122510045555_,1.584754263,-0.47542381,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,enoxaparin,DB01225
,27600,DB01109,10062506,186,4226,282,3988,8.98311098129975e-07,0.622467941,0.511797431,0.755687,1.30417604056042e-05,DB0110910062506_,11.24735401,-0.474063153,NA,10062506,Heparin-induced thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,heparin,DB01109
,27605,DB01109,10020646,17,4395,49,4221,3.60688214301353e-05,0.333237721,0.17960917,0.589981502,0.000333592,DB0110910020646_,8.005591334,-1.098899168,male,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,heparin,DB01109
,27610,DB00682,10022592,156,19303,207,16157,1.65987523557249e-05,0.630813858,0.508595016,0.781132064,0.000169403,DB0068210022592_,8.68322828,-0.460744456,NA,10022592,International normalised ratio abnormal,10022891,Investigations,Inv,warfarin,DB00682
,27611,DB00682,10051055,259,19200,272,16092,0.010852718,0.798076213,0.669684646,0.950865199,0.038012351,DB0068210051055_,3.269844143,-0.225551181,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,warfarin,DB00682
,27612,DB01115,10013709,118,3482,72,2196,0.879693535,1.033598116,0.760566319,1.412705794,0.949457398,DB0111510013709_,0.051864617,0.033046031,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,27621,DB00203,10005728,56,13822,21,8917,0.034974598,1.720308527,1.024487163,2.993532491,0.095372127,DB0020310005728_,2.349968916,0.542503651,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,sildenafil,DB00203
,27622,DB08896,10011906,61,762,84,956,0.602808298,0.911147299,0.635120288,1.301029644,0.74658701,DB0889610011906_,0.292243112,-0.093050706,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,regorafenib,DB08896
,27623,DB05676,10013946,515,46614,254,25075,0.270336319,1.090689337,0.935882784,1.273614267,0.433026787,DB0567610013946_,0.83695569,0.086809915,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,27624,DB05676,10028735,148,46981,68,25261,0.317098468,1.170235908,0.872046837,1.584089754,0.484885147,DB0567610028735_,0.723843227,0.157205359,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,27625,DB05676,10039101,192,46937,118,25211,0.256970969,0.873971853,0.690937668,1.109302847,0.417859007,DB0567610039101_,0.872611208,-0.134707108,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,27626,DB05676,10050584,104,47025,28,25301,0.000686467,1.99838967,1.305535435,3.152393973,0.00402718,DB0567610050584_,5.514688973,0.692341691,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,apremilast,DB05676
,27627,DB06403,10003239,441,21030,139,6522,0.882299711,0.983932548,0.809608246,1.201822275,0.950859822,DB0640310003239_,0.050388628,-0.016197933,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,27628,DB00374,10016326,56,17660,15,5709,0.581921649,1.206871753,0.672607712,2.299536376,0.73014514,DB0037410016326_,0.314511942,0.188031683,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,27631,DB01267,10019070,64,2788,109,3606,0.087506292,0.75945967,0.54659065,1.047962024,0.190978934,DB0126710019070_,1.65559215,-0.275148059,NA,10019070,"Hallucination, auditory",10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,27632,DB00682,10063351,114,19345,88,16276,0.571364556,1.089966108,0.817380786,1.457461286,0.72156175,DB0068210063351_,0.326337319,0.086146602,NA,10063351,International normalised ratio fluctuation,10022891,Investigations,Inv,warfarin,DB00682
,27633,DB00635,10022595,41,33012,54,23740,0.003464275,0.546026365,0.354575555,0.835150848,0.015196672,DB0063510022595_,4.186678838,-0.605088017,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,prednisone,DB00635
,27636,DB00563,10029216,75,46571,6,15342,8.58001852240833e-05,4.117935185,1.805218504,11.57915034,0.000699956,DB0056310029216_,7.264493243,1.415351869,female,10029216,Nervousness,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,27644,DB08934,10047513,19,4470,44,6160,0.072215008,0.595107362,0.32765166,1.042380877,0.165144553,DB0893410047513_,1.800934111,-0.519013449,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,sofosbuvir,DB08934
,27655,DB00958,10041101,46,4548,10,2575,0.004704609,2.604140565,1.293507686,5.796845748,0.01947565,DB0095810041101_,3.938590337,0.957102703,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,carboplatin,DB00958
,27656,DB01229,10041101,55,5686,11,2698,0.007534029,2.37229241,1.225610982,5.035739339,0.028389642,DB0122910041101_,3.561730917,0.863856749,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,paclitaxel,DB01229
,27662,DB00316,10029174,49,65425,29,36924,0.906185952,0.953602661,0.590442045,1.56588264,0.958144782,DB0031610029174_,0.042756383,-0.047508192,NA,10029174,Nerve compression,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,27664,DB00480,10029174,44,67384,35,67627,0.313382919,1.261671296,0.790909488,2.026416768,0.48091018,DB0048010029174_,0.732074762,0.232437268,NA,10029174,Nerve compression,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,27669,DB00682,10033425,659,18800,288,16076,3.14186061726676e-22,1.956608475,1.698260749,2.258748042,4.06816779925403e-20,DB0068210033425_,44.64850913,0.671212604,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,27670,DB00374,10033433,727,16989,199,5525,0.03503381,1.188066374,1.011151882,1.401010111,0.095469358,DB0037410033433_,2.348949943,0.172327089,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,27671,DB00682,10033433,492,18967,136,16228,1.5451378023056e-36,3.094969674,2.551764289,3.775317961,5.20691629917982e-34,DB0068210033433_,76.63790536,1.129778108,female,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,27676,DB00222,10003658,28,3178,48,3080,0.020390838,0.565399124,0.340624357,0.922285512,0.062749304,DB0022210003658_,2.7686078,-0.570223383,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,glimepiride,DB00222
,27677,DB00575,10003658,50,5194,30,3799,0.427324661,1.219008139,0.758540321,1.989646381,0.595890008,DB0057510003658_,0.517699178,0.198037527,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,clonidine,DB00575
,27678,DB00575,10007559,59,5185,49,3780,0.556692755,0.877821456,0.589320585,1.312641131,0.71001354,DB0057510007559_,0.342471238,-0.130312059,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,clonidine,DB00575
,27682,DB00222,10020772,40,3166,42,3086,0.740466793,0.928351539,0.584961779,1.47122098,0.850923344,DB0022210020772_,0.161433232,-0.074344805,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,glimepiride,DB00222
,27684,DB00973,10020772,67,3784,41,2980,0.240882921,1.286885826,0.856958089,1.953235375,0.398929374,DB0097310020772_,0.918970884,0.252225211,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ezetimibe,DB00973
,27685,DB00480,10001949,222,67206,185,67477,0.066138332,1.204835418,0.986507484,1.472851783,0.154412647,DB0048010001949_,1.868126737,0.186342975,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,27701,DB06204,10013709,83,729,33,346,0.46313719,1.193610323,0.770987694,1.883401024,0.630278589,DB0620410013709_,0.461593352,0.176982599,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tapentadol,DB06204
,27724,DB00682,10007515,138,19321,145,16219,0.063266353,0.798932698,0.627594351,1.016678357,0.149414908,DB0068210007515_,1.901028228,-0.22447857,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,warfarin,DB00682
,27725,DB06403,10007515,102,21369,46,6615,0.041199776,0.686427327,0.479527574,0.99574701,0.108104429,DB0640310007515_,2.224657587,-0.37625492,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,ambrisentan,DB06403
,27726,DB01394,10010264,47,1393,29,1974,0.000557804,2.296110785,1.407511661,3.80353396,0.003378703,DB0139410010264_,5.690263343,0.831216728,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,colchicine,DB01394
,27729,DB00512,10002198,68,4669,62,5036,0.377104224,1.182962402,0.824029855,1.700894066,0.547014957,DB0051210002198_,0.603279133,0.168021802,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,vancomycin,DB00512
,27730,DB00512,10007515,91,4646,94,5004,0.823762805,1.042692781,0.770646005,1.410217984,0.906573661,DB0051210007515_,0.098082993,0.041806579,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,vancomycin,DB00512
,27732,DB00787,10033661,155,16845,225,17023,0.000536044,0.696178831,0.563018066,0.85903366,0.003268364,DB0078710033661_,5.723465714,-0.362148711,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,acyclovir,DB00787
,27733,DB00996,10033661,117,38836,103,22322,0.00196222,0.65293456,0.49640997,0.859787486,0.009584654,DB0099610033661_,4.647592013,-0.426278369,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,gabapentin,DB00996
,27734,DB08910,10033661,79,16665,124,17364,0.004750163,0.663830105,0.493777754,0.888060962,0.019627137,DB0891010033661_,3.930842111,-0.409729028,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,pomalidomide,DB08910
,27738,DB01229,10013971,40,5701,12,2697,0.181909098,1.576838678,0.809406608,3.307412959,0.326309069,DB0122910013971_,1.119910281,0.455422006,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,paclitaxel,DB01229
,27739,DB00019,10025482,186,18826,59,9470,0.001707297,1.585792436,1.175966418,2.165492549,0.008537299,DB0001910025482_,4.763310607,0.461084242,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,27741,DB00958,10025482,74,4520,33,2552,0.310204245,1.266061846,0.82668034,1.976363926,0.477635674,DB0095810025482_,0.738907026,0.235911174,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,27742,DB01229,10025482,120,5621,30,2679,0.00105604,1.906294253,1.265020504,2.955130233,0.005764862,DB0122910025482_,5.155974123,0.645161176,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,27743,DB00958,10037660,185,4409,103,2482,0.950127449,1.01110349,0.7861663,1.306151144,0.988407804,DB0095810037660_,0.011659909,0.011042298,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,27752,DB00175,10037844,206,7925,144,5962,0.512295049,1.076224156,0.863230721,1.344657704,0.672497471,DB0017510037844_,0.396756928,0.073458763,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,pravastatin,DB00175
,27753,DB00404,10037844,512,19380,162,9700,2.11169969551079e-07,1.581854954,1.320758383,1.902661179,3.56493426438672e-06,DB0040410037844_,12.54436494,0.45859818,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,27754,DB01118,10037844,38,3025,74,4635,0.243890665,0.786849185,0.516145984,1.182304109,0.402326229,DB0111810037844_,0.910492004,-0.239718682,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,amiodarone,DB01118
,27755,DB01394,10037844,49,1391,49,1954,0.097643776,1.404579664,0.919882794,2.144753576,0.207374189,DB0139410037844_,1.57323044,0.339738086,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,colchicine,DB01394
,27756,DB06228,10037844,331,15581,259,15817,0.001822655,1.297334945,1.097590801,1.534740455,0.009015521,DB0622810037844_,4.708807587,0.260312118,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,rivaroxaban,DB06228
,27757,DB09270,10037844,111,3003,58,2310,0.018003507,1.472045527,1.056822758,2.068769379,0.056858312,DB0927010037844_,2.867192862,0.386652948,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ubidecarenone,DB09270
,27758,DB00175,10050584,79,8052,38,6068,0.0241564,1.566648332,1.049443392,2.375213797,0.071592171,DB0017510050584_,2.636769559,0.448938517,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,27759,DB00335,10050584,78,8388,44,5421,0.514998107,1.145702419,0.78050068,1.700529283,0.674879113,DB0033510050584_,0.393221696,0.136017915,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,atenolol,DB00335
,27760,DB00404,10050584,188,19704,47,9815,1.01795676077751e-05,1.992447668,1.439139367,2.807318842,0.000110299,DB0040410050584_,9.112312339,0.689363867,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,27761,DB01118,10050584,29,3034,32,4677,0.191608332,1.396918001,0.813523258,2.389685805,0.338628724,DB0111810050584_,1.082850982,0.334268382,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,amiodarone,DB01118
,27763,DB06228,10050584,217,15695,187,15889,0.109375699,1.174764176,0.960396561,1.438070122,0.225132361,DB0622810050584_,1.49106678,0.161067427,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,27764,DB09270,10050584,43,3071,29,2339,0.6342731,1.129274184,0.686687137,1.881827829,0.772596897,DB0927010050584_,0.257997846,0.121575112,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,ubidecarenone,DB09270
,27775,DB00273,10037087,136,8345,22,2171,0.037192344,1.608149964,1.017160432,2.657811402,0.099936341,DB0027310037087_,2.303221887,0.475084428,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,topiramate,DB00273
,27776,DB01224,10037087,66,8042,28,5889,0.015661676,1.726019983,1.092201584,2.793597406,0.050996241,DB0122410037087_,2.976003364,0.54581817,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,quetiapine,DB01224
,27777,DB00273,10037844,187,8294,47,2146,0.934819033,1.029465532,0.741235832,1.454588476,0.975184279,DB0027310037844_,0.025128822,0.029039766,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,topiramate,DB00273
,27778,DB01224,10037844,116,7992,63,5854,0.05722203,1.348668729,0.982071391,1.866766012,0.138217337,DB0122410037844_,1.978927929,0.299117979,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,quetiapine,DB01224
,27781,DB00068,10011906,79,2155,42,623,0.002687925,0.543924979,0.365255027,0.819738407,0.012364735,DB0006810011906_,4.392906802,-0.608943949,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,27782,DB00374,10016100,40,17676,23,5701,0.038305608,0.560937963,0.327506604,0.982368363,0.102245536,DB0037410016100_,2.280378142,-0.578144963,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,27784,DB00374,10017955,199,17517,70,5654,0.52148633,0.917589253,0.694230524,1.224901448,0.680312093,DB0037410017955_,0.385203626,-0.086005425,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,27785,DB00374,10018627,60,17656,49,5675,2.92734622842108e-06,0.393594443,0.26503694,0.587013617,3.70820701754448e-05,DB0037410018627_,10.20237699,-0.932434233,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,treprostinil,DB00374
,27786,DB00559,10018627,43,9616,19,3287,0.380483514,0.773622828,0.440545701,1.407792767,0.550519317,DB0055910018627_,0.596893234,-0.256670827,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,bosentan,DB00559
,27787,DB00559,10033425,244,9415,62,3244,0.03362063,1.355940315,1.019089273,1.82744355,0.092632942,DB0055910033425_,2.379110456,0.304495173,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,bosentan,DB00559
,27788,DB00374,10039710,103,17613,7,5717,1.01953067566768e-06,4.775983269,2.234834389,12.18263271,1.45445665182768e-05,DB0037410039710_,11.13829307,1.563599873,female,10039710,Scleroderma,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,27798,DB00316,10049177,36,65438,23,36930,0.684650725,0.883336868,0.509244022,1.561533921,0.809556863,DB0031610049177_,0.211268263,-0.124048647,NA,10049177,Drug screen positive,10022891,Investigations,Inv,acetaminophen,DB00316
,27800,DB00182,10074903,54,5140,46,2806,0.034796562,0.640866636,0.423229467,0.974008359,0.09503612,DB0018210074903_,2.353498247,-0.444933899,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,amphetamine,DB00182
,27801,DB00316,10074903,715,64759,374,36579,0.240546977,1.079864124,0.950909121,1.227851461,0.398511111,DB0031610074903_,0.9200199,0.076835222,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,27803,DB00471,10002424,35,14154,16,5449,0.53584124,0.842172775,0.453537139,1.630995469,0.692321422,DB0047110002424_,0.367704949,-0.17177009,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,27804,DB00584,10002424,18,2063,57,1817,4.85025268882775e-07,0.27821644,0.153518322,0.481798566,7.55265947427947e-06,DB0058410002424_,11.79361081,-1.279355906,male,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,enalapril,DB00584
,27805,DB00996,10002424,49,38904,40,22385,0.122429562,0.704882662,0.454575663,1.098762628,0.24492435,DB0099610002424_,1.406805891,-0.349723926,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,27807,DB01136,10002424,52,9832,34,11081,0.016744024,1.723637023,1.096528643,2.741651184,0.053725181,DB0113610002424_,2.923873465,0.544436606,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,carvedilol,DB01136
,27810,DB00471,10038695,106,14083,47,5418,0.415854609,0.867685363,0.608955087,1.252652052,0.585047684,DB0047110038695_,0.536061924,-0.141926115,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,27811,DB00575,10038695,38,5206,44,3785,0.042633008,0.627949384,0.395022317,0.994049438,0.11098981,DB0057510038695_,2.198316888,-0.465295714,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonidine,DB00575
,27813,DB01136,10038695,107,9777,100,11015,0.184329477,1.205473705,0.907861756,1.601670786,0.329336882,DB0113610038695_,1.110674093,0.186872606,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,27815,DB00338,10042727,66,33608,31,22241,0.120246208,1.408935656,0.906025132,2.234925907,0.241697424,DB0033810042727_,1.420068649,0.342834565,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,27819,DB00996,10042727,66,38887,22,22403,0.026342162,1.728299972,1.052437855,2.94222606,0.076520329,DB0099610042727_,2.570198841,0.54713825,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,27825,DB00343,10037087,133,8603,60,5035,0.098667208,1.297304848,0.947472569,1.793926204,0.208864264,DB0034310037087_,1.566070691,0.260288918,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,diltiazem,DB00343
,27826,DB00627,10037087,47,1282,24,1575,0.000413075,2.405210413,1.432382162,4.136394253,0.002631848,DB0062710037087_,5.940069027,0.87763739,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,niacin,DB00627
,27827,DB00257,10037844,43,909,13,609,0.01178246,2.215028234,1.157232372,4.52905945,0.040579398,DB0025710037844_,3.204494787,0.79526515,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,clotrimazole,DB00257
,27828,DB00343,10037844,190,8546,108,4987,0.85564915,1.026611262,0.804181752,1.316007145,0.930234222,DB0034310037844_,0.072318873,0.026263342,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,diltiazem,DB00343
,27829,DB00627,10037844,57,1272,31,1568,0.000286889,2.265973315,1.428525627,3.654687447,0.001945529,DB0062710037844_,6.242221502,0.818004386,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,niacin,DB00627
,27830,DB08900,10028813,104,907,33,404,0.117403694,1.403451745,0.922355698,2.18256451,0.237290234,DB0890010028813_,1.438471271,0.338934734,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,teduglutide,DB08900
,27835,DB00706,10028411,8,1067,138,15787,0.863849385,0.85772337,0.362102828,1.744318047,0.937288439,DB0070610028411_,0.064764211,-0.153473644,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tamsulosin,DB00706
,27836,DB01156,10028411,117,13505,30,6298,0.002455343,1.818700168,1.207516629,2.817903154,0.011502173,DB0115610028411_,4.465219318,0.598122052,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,27837,DB01175,10028411,106,10618,34,4858,0.081622711,1.426395008,0.959536762,2.168838867,0.181060596,DB0117510028411_,1.708923518,0.355150288,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,27838,DB00537,10053762,181,7376,143,4155,0.003340019,0.713051787,0.567504469,0.897233029,0.014751305,DB0053710053762_,4.216423706,-0.338201228,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ciprofloxacin,DB00537
,27839,DB00706,10053762,28,1047,356,15569,0.39720257,1.169546414,0.762212563,1.730114168,0.566846896,DB0070610053762_,0.567666036,0.156615993,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tamsulosin,DB00706
,27840,DB01098,10053762,236,7913,187,7022,0.25635896,1.119908122,0.917902899,1.367984867,0.41718337,DB0109810053762_,0.874229417,0.113246648,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,rosuvastatin,DB01098
,27847,DB00363,10016173,66,4562,92,6796,0.683683385,1.06868932,0.765159889,1.485657631,0.808795076,DB0036310016173_,0.2122097,0.066432963,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,clozapine,DB00363
,27848,DB06403,10053762,331,21140,176,6485,1.85789674286822e-08,0.576939636,0.478004748,0.698208277,3.91932711767987e-07,DB0640310053762_,14.75217567,-0.550017636,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ambrisentan,DB06403
,27856,DB01075,10003285,45,19903,16,11081,0.141243917,1.565838562,0.867737159,2.969317378,0.271616955,DB0107510003285_,1.30336246,0.448421503,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,27860,DB01075,10006784,93,19855,43,11054,0.325714009,1.204064001,0.829558789,1.772455809,0.494192607,DB0107510006784_,0.704829945,0.185702503,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,27861,DB00073,10007559,27,7379,35,6372,0.125742135,0.666179156,0.387346079,1.13417823,0.249679472,DB0007310007559_,1.387577296,-0.406196641,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,rituximab,DB00073
,27862,DB01075,10007559,65,19883,50,11047,0.097034509,0.722313814,0.491506241,1.066970415,0.206333556,DB0107510007559_,1.578261215,-0.32529559,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,27863,DB00073,10010264,66,7340,39,6368,0.061929395,1.468159917,0.97211548,2.244065344,0.147027427,DB0007310010264_,1.917136135,0.38400986,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,27864,DB01075,10010264,197,19751,72,11025,0.002101909,1.527276196,1.159065556,2.031569012,0.010134582,DB0107510010264_,4.591801791,0.423485885,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,27865,DB01075,10017577,147,19801,60,11037,0.041771314,1.365607251,1.003857538,1.877793272,0.10926596,DB0107510017577_,2.213970371,0.311599202,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,27866,DB00073,10020937,85,7321,37,6370,0.000344149,1.998737312,1.341409008,3.030281209,0.00226347,DB0007310020937_,6.0908562,0.692515637,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,rituximab,DB00073
,27867,DB01075,10020937,240,19708,77,11020,1.21310235400491e-05,1.742818566,1.341374522,2.285777193,0.000128652,DB0107510020937_,8.958399562,0.555503668,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,27869,DB01075,10028391,102,19846,42,11055,0.116346792,1.352796832,0.934983407,1.988310618,0.235669133,DB0107510028391_,1.445326435,0.302174177,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,27876,DB00073,10033775,57,7349,35,6372,0.116073693,1.412025955,0.909724914,2.219735163,0.235271207,DB0007310033775_,1.447016356,0.345025521,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,rituximab,DB00073
,27877,DB01075,10033775,220,19728,70,11027,2.59250701070374e-05,1.756675243,1.335269157,2.335537903,0.000249201,DB0107510033775_,8.297250269,0.563422956,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,27878,DB00073,10037087,232,7174,139,6268,0.000484603,1.458236212,1.1732912,1.817740791,0.003013438,DB0007310037087_,5.80467375,0.377227631,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,rituximab,DB00073
,27880,DB01075,10037855,70,19878,32,11065,0.407998971,1.217615734,0.790134166,1.913584281,0.577426462,DB0107510037855_,0.549174184,0.19689463,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,27886,DB00073,10038435,40,7366,62,6345,0.003743587,0.55576565,0.363316248,0.841622156,0.016167529,DB0007310038435_,4.124750441,-0.587408567,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,rituximab,DB00073
,27887,DB01075,10038435,83,19865,70,11027,0.011065545,0.658166571,0.47261766,0.918829552,0.038578593,DB0107510038435_,3.255057755,-0.418297233,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,diphenhydramine,DB01075
,27889,DB01075,10040831,44,19904,12,11085,0.025410253,2.042008323,1.059600221,4.249117917,0.07439805,DB0107510040831_,2.598325554,0.713933796,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,27890,DB00073,10042674,47,7359,29,6378,0.166725931,1.404604669,0.86470907,2.317117592,0.306428772,DB0007310042674_,1.182769941,0.339755889,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,27891,DB01075,10042674,159,19789,63,11034,0.02428093,1.407217164,1.043739963,1.917085865,0.07190449,DB0107510042674_,2.632416567,0.341614111,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,27898,DB01075,10060800,74,19874,12,11085,8.08290775747827e-06,3.439431113,1.855198749,6.958269084,9.03313054444373e-05,DB0107510060800_,9.312026475,1.235306083,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,diphenhydramine,DB01075
,27900,DB01075,10061024,60,19888,33,11064,1,1.011482301,0.650358448,1.598186943,1,DB0107510061024_,0,0.01141688,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,27903,DB00455,10013709,345,9056,154,4964,0.040232473,1.227924684,1.009271162,1.499529134,0.10611716,DB0045510013709_,2.243211514,0.205325496,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,27904,DB00455,10016256,684,8717,305,4813,0.002689712,1.238190332,1.075236357,1.428409569,0.012370793,DB0045510016256_,4.392416959,0.213650904,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,27906,DB00455,10025482,314,9087,99,5019,6.22479889236188e-07,1.751763592,1.389353984,2.224624495,9.41149490283187e-06,DB0045510025482_,11.57357875,0.560623047,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,27907,DB00455,10028813,651,8750,196,4922,5.09787494109721e-15,1.868274618,1.583787546,2.211596131,3.13078604735374e-13,DB0045510028813_,28.7923221,0.625015341,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,27908,DB00973,10013700,214,3637,82,2939,4.79715939705234e-09,2.108639237,1.619380786,2.767512279,1.15681958487634e-07,DB0097310013700_,15.97242115,0.746042828,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ezetimibe,DB00973
,27909,DB01202,10028411,35,6679,25,5693,0.519258701,1.19330477,0.693177053,2.082664306,0.678466717,DB0120210028411_,0.387919855,0.176726576,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,levetiracetam,DB01202
,27910,DB00186,10040984,72,16829,30,9978,0.123233562,1.42295424,0.916745852,2.258967511,0.245989837,DB0018610040984_,1.402465059,0.352735161,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,27912,DB00186,10042209,82,16819,19,9989,7.55450493884065e-05,2.563114946,1.540685779,4.475036788,0.0006268,DB0018610042209_,7.374883439,0.941223294,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,27920,DB01224,10022437,187,7921,146,5771,0.537307171,0.933172953,0.745415176,1.170004955,0.693482555,DB0122410022437_,0.366029194,-0.069164722,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,27925,DB00656,10042209,68,11945,20,6599,0.01354478,1.878267362,1.125754031,3.268515119,0.04532746,DB0065610042209_,3.093842254,0.630349736,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,27926,DB00829,10042209,56,7996,12,4442,0.001397995,2.592288681,1.371647928,5.318850262,0.007250653,DB0082910042209_,4.926663799,0.952541146,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,27927,DB01175,10042209,67,10657,22,4870,0.207398032,1.391711527,0.847478502,2.369240378,0.358094871,DB0117510042209_,1.026957325,0.330534304,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,27928,DB00656,10061422,45,11968,43,6576,0.010145286,0.575011392,0.369648686,0.895612866,0.035980414,DB0065610061422_,3.32478054,-0.553365427,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,27937,DB00338,10029148,113,33561,80,22192,0.658836362,0.934008383,0.694856899,1.260446928,0.791655557,DB0033810029148_,0.233628884,-0.068269865,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,27941,DB00722,10029148,66,25337,65,25967,0.861260982,1.04064362,0.727186506,1.489549226,0.935039648,DB0072210029148_,0.067166346,0.039839387,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,27943,DB08908,10029148,45,10628,28,3251,0.005090884,0.491619752,0.299571638,0.819815684,0.020754385,DB0890810029148_,3.874997751,-0.710049722,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,dimethyl fumarate,DB08908
,27944,DB01041,10062355,69,2976,89,3029,0.147612544,0.789120043,0.565283873,1.097678208,0.280670987,DB0104110062355_,1.270572162,-0.236836824,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,thalidomide,DB01041
,27945,DB00005,10005956,177,127905,40,42379,0.02769234,1.466108384,1.035132674,2.121969191,0.079555512,DB0000510005956_,2.53130024,0.382611533,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,27946,DB00563,10005956,43,46603,16,15332,0.652518308,0.884152023,0.487839269,1.682129286,0.786745429,DB0056310005956_,0.239850553,-0.123126259,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,27950,DB00338,10015967,71,33603,34,22238,0.134429579,1.381956728,0.905647629,2.146279245,0.26185575,DB0033810015967_,1.339961501,0.323500414,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,omeprazole,DB00338
,27951,DB00451,10034829,65,47206,14,15405,0.190509348,1.515084025,0.841230492,2.924471014,0.337185534,DB0045110034829_,1.087121954,0.4154709,NA,10034829,Pharyngeal oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,27954,DB00635,10042945,145,32908,13,23781,4.37639313208065e-21,8.061702144,4.56614366,15.50637072,5.12398634640266e-19,DB0063510042945_,42.11518405,2.087124718,female,10042945,Systemic lupus erythematosus,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,27963,DB00559,10064685,35,9624,24,3282,0.010416018,0.497334571,0.287083678,0.87534189,0.036759535,DB0055910064685_,3.303357619,-0.698492298,NA,10064685,Device occlusion,10077536,Product issues,Prod,bosentan,DB00559
,27965,DB00567,10025482,121,4398,27,2054,0.000314578,2.092787342,1.364750968,3.315917436,0.002098648,DB0056710025482_,6.166462074,0.738496834,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,27967,DB00068,10020937,76,2158,31,634,0.129260352,0.720349083,0.463715158,1.143012128,0.254540632,DB0006810020937_,1.368294803,-0.328019347,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,interferon beta-1b,DB00068
,27968,DB00068,10049848,47,2187,22,643,0.081849077,0.628225279,0.36796201,1.103417555,0.181461117,DB0006810049848_,1.706713881,-0.464856452,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,interferon beta-1b,DB00068
,27971,DB01224,10033557,43,8065,25,5892,0.391009431,1.256549663,0.749361592,2.149396015,0.560840516,DB0122410033557_,0.578318698,0.228369602,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,quetiapine,DB01224
,27972,DB01224,10064355,21,8087,32,5885,0.00802626,0.477580292,0.261442633,0.855137192,0.029861324,DB0122410064355_,3.511191135,-0.739022983,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,27974,DB00526,10016825,32,1566,28,1866,0.242273242,1.361663369,0.790351261,2.358501896,0.400531564,DB0052610016825_,0.914962703,0.308707018,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,oxaliplatin,DB00526
,27975,DB00673,10016825,49,618,13,328,0.026876259,1.999273949,1.04937579,4.077826164,0.077742102,DB0067310016825_,2.554358318,0.692784089,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,aprepitant,DB00673
,27977,DB01234,10016825,166,31459,118,32770,0.001580462,1.465387438,1.149740345,1.872594539,0.008018227,DB0123410016825_,4.826038013,0.382119671,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,dexamethasone,DB01234
,27981,DB01234,10033775,338,31287,218,32670,2.66001568060231e-08,1.618970703,1.360481535,1.929781724,5.43056405162188e-07,DB0123410033775_,14.42605265,0.481790579,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,27983,DB01050,10011906,452,17656,393,8978,4.06315363766045e-14,0.584826513,0.508518711,0.672877644,2.18181804629019e-12,DB0105010011906_,26.85086262,-0.536440036,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,27992,DB00563,10001949,64,46582,16,15332,0.365918007,1.316541056,0.751963046,2.440754228,0.535502188,DB0056310001949_,0.624550303,0.275007885,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,28000,DB00563,10008479,266,46380,94,15254,0.540734195,0.930687802,0.732432251,1.191265378,0.69622319,DB0056310008479_,0.362084995,-0.071831394,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,28001,DB00993,10008479,54,3195,21,1598,0.387639043,1.286096557,0.760854265,2.250194246,0.557649468,DB0099310008479_,0.584024708,0.251611706,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,azathioprine,DB00993
,28002,DB01281,10008479,52,8880,9,1789,0.863225828,1.163997952,0.567049487,2.691719318,0.936805644,DB0128110008479_,0.065279442,0.15186059,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,28003,DB00993,10013709,359,2890,137,1482,0.00483873,1.343677095,1.089225179,1.664677685,0.019944489,DB0099310013709_,3.914802419,0.295409957,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,azathioprine,DB00993
,28004,DB01281,10013709,2150,6782,411,1387,0.275228995,1.06982876,0.947433777,1.209687323,0.438529311,DB0128110013709_,0.824328625,0.067498598,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,28005,DB00993,10025482,91,3158,26,1593,0.009698279,1.765330312,1.125620722,2.857132513,0.034732511,DB0099310025482_,3.360079106,0.568337819,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,azathioprine,DB00993
,28006,DB01281,10025482,260,8672,34,1764,0.014022744,1.5554485,1.080673797,2.30313198,0.046653735,DB0128110025482_,3.065002282,0.441763929,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,28014,DB00005,10045285,79,128003,26,42393,1,1.006301205,0.638778849,1.633771959,1,DB0000510045285_,0,0.006281435,NA,10045285,Ulcer,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,28016,DB00563,10045285,54,46592,14,15334,0.484127348,1.26941925,0.695159084,2.475351335,0.64835621,DB0056310045285_,0.433315027,0.238559513,NA,10045285,Ulcer,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,28020,DB00563,10047340,68,46578,19,15329,0.619272265,1.177839103,0.69955575,2.075493736,0.760083654,DB0056310047340_,0.274326781,0.163681491,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,methotrexate,DB00563
,28023,DB00993,10047895,46,3203,37,1582,0.033835232,0.614103333,0.387921818,0.97808168,0.093039237,DB0099310047895_,2.374733977,-0.48759207,NA,10047895,Weight decreased,10022891,Investigations,Inv,azathioprine,DB00993
,28024,DB01281,10047895,60,8872,12,1786,1,1.006537022,0.53459628,2.059985662,1,DB0128110047895_,0,0.006515749,NA,10047895,Weight decreased,10022891,Investigations,Inv,abatacept,DB01281
,28026,DB00563,10058080,135,46511,62,15286,0.031555633,0.715620753,0.52568628,0.98351733,0.088135504,DB0056310058080_,2.428879827,-0.334604927,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,28034,DB00051,10001760,701,25030,60,11360,6.37288695122694e-54,5.302778141,4.065296174,7.029750401,4.46696889368e-51,DB0005110001760_,115.9351297,1.668230861,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,28035,DB01281,10001760,168,8764,8,1790,1.11212163091057e-06,4.288794203,2.12198016,10.11590029,1.57161919723034e-05,DB0128110001760_,11.06081904,1.456005622,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,abatacept,DB01281
,28036,DB00051,10003246,239,25492,105,11315,0.953260327,1.010323581,0.798985104,1.284783509,0.991235371,DB0005110003246_,0.008803265,0.010270657,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,28037,DB00563,10003246,362,46284,114,15234,0.709273767,1.045199381,0.843829947,1.302715198,0.826495588,DB0056310003246_,0.1905607,0.044207663,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,28038,DB01281,10003246,84,8848,13,1785,0.493753712,1.303522687,0.720515041,2.555062471,0.656462072,DB0128110003246_,0.420890359,0.265070359,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,abatacept,DB01281
,28039,DB00051,10022093,312,25419,50,11370,7.05132728674973e-14,2.791108961,2.063531728,3.845090646,3.69565171176946e-12,DB0005110022093_,26.3238642,1.026438994,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,28041,DB00051,10022094,181,25550,38,11382,8.87222277225042e-06,2.12185223,1.487660541,3.09746052,9.78009543168808e-05,DB0005110022094_,9.232576223,0.752289401,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,28043,DB00051,10048334,194,25537,57,11363,0.005913406,1.514425424,1.120867415,2.07392662,0.023398144,DB0005110048334_,3.755098575,0.415036109,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,28044,DB00563,10048334,352,46294,95,15253,0.0882332,1.220804439,0.96991442,1.549162637,0.192309037,DB0056310048334_,1.648651632,0.199510018,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,28046,DB00563,10061156,67,46579,21,15327,0.902255474,1.049806134,0.634638802,1.80552245,0.957195726,DB0056310061156_,0.043747388,0.048605513,NA,10061156,Finger deformity,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,28049,DB00563,10061159,115,46531,18,15330,0.0017706,2.104716133,1.273681102,3.678550477,0.008796941,DB0056310061159_,4.733351252,0.744180604,NA,10061159,Foot deformity,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,28052,DB00480,10028596,283,67145,550,67112,1.56535167113818e-20,0.514298111,0.443824548,0.594901358,1.72853517102692e-18,DB0048010028596_,40.89925735,-0.664952198,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,28053,DB00480,10037377,652,66776,808,66854,5.59988366343142e-05,0.807876122,0.727145135,0.8973003,0.000486508,DB0048010037377_,7.628257575,-0.213346547,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,28055,DB00563,10027599,212,46434,27,15321,2.46785152314345e-07,2.590833095,1.730021418,4.025652784,4.10423772767008e-06,DB0056310027599_,12.40349053,0.951979482,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,28056,DB00921,10024855,43,5802,31,4872,0.559340076,1.164742745,0.715821374,1.915168532,0.712094248,DB0092110024855_,0.339545005,0.152500242,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,buprenorphine,DB00921
,28057,DB01156,10024855,84,13538,31,6297,0.314962345,1.260319272,0.824836107,1.971408476,0.482529978,DB0115610024855_,0.72871223,0.231365079,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,28058,DB01175,10024855,71,10653,46,4846,0.071265194,0.70212683,0.47698724,1.042491249,0.16346312,DB0117510024855_,1.811167877,-0.353641222,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,28066,DB00472,10010264,205,10554,92,4220,0.364341601,0.890981335,0.691486497,1.155292719,0.533983048,DB0047210010264_,0.627391186,-0.1154318,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,28067,DB00734,10010264,97,3953,84,4818,0.023653188,1.407379818,1.036645299,1.91391742,0.070422388,DB0073410010264_,2.653244058,0.341729691,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,28076,DB06605,10003285,69,14004,51,12982,0.234580913,1.254192307,0.860001946,1.839632593,0.391449575,DB0660510003285_,0.937898573,0.226491785,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,28082,DB00005,10044016,154,127928,55,42364,0.631232769,0.927226912,0.677219681,1.285983199,0.770079966,DB0000510044016_,0.261260917,-0.075556963,NA,10044016,Tooth abscess,10021881,Infections and infestations,Infec,etanercept,DB00005
,28086,DB00046,10013700,71,5388,32,4660,0.001971792,1.918840633,1.244867155,3.016557231,0.009621042,DB0004610013700_,4.643802701,0.651721167,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,insulin lispro,DB00046
,28089,DB00334,10013700,40,2809,19,2793,0.008383602,2.092998888,1.180823034,3.83637573,0.030910784,DB0033410013700_,3.476650152,0.738597912,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,olanzapine,DB00334
,28090,DB00864,10013700,44,6825,24,8368,0.001336444,2.247711296,1.335738709,3.868802678,0.006990733,DB0086410013700_,4.963169846,0.809912497,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,tacrolimus,DB00864
,28091,DB00959,10013700,417,7661,78,4924,1.00569789346886e-28,3.435867986,2.684347427,4.4455245,2.0571804770295e-26,DB0095910013700_,59.14587607,1.234269582,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,methylprednisolone,DB00959
,28094,DB01413,10013700,44,1176,24,1635,0.000255925,2.548072146,1.506339776,4.407125162,0.001770494,DB0141310013700_,6.336496563,0.935337052,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,cefepime,DB01413
,28095,DB09153,10013700,49,7750,23,5676,0.093357454,1.560251838,0.931375443,2.68636131,0.200706198,DB0915310013700_,1.605913141,0.444847243,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,sodium chloride,DB09153
,28098,DB00047,10024378,20,9265,38,8480,0.008080619,0.481745395,0.26533709,0.849726667,0.030033804,DB0004710024378_,3.505431744,-0.730339532,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,insulin glargine,DB00047
,28105,DB00864,10024378,24,6845,32,8360,0.789004842,0.915976368,0.515743635,1.606516497,0.88567613,DB0086410024378_,0.121403937,-0.087764714,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,tacrolimus,DB00864
,28106,DB00959,10024378,32,8046,35,4967,0.02270839,0.564459641,0.337856378,0.939998543,0.0682199,DB0095910024378_,2.685018962,-0.571886394,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,methylprednisolone,DB00959
,28113,DB00009,10037660,41,1310,38,1513,0.36120582,1.246043315,0.77645099,2.004049568,0.531119657,DB0000910037660_,0.63276794,0.219973183,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,alteplase,DB00009
,28114,DB00046,10037660,89,5370,99,4593,0.076652475,0.768936929,0.569307773,1.037311489,0.172641301,DB0004610037660_,1.756539243,-0.26274633,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,28115,DB00047,10037660,134,9151,142,8376,0.2485805,0.863751244,0.675692877,1.103676723,0.407969716,DB0004710037660_,0.896562332,-0.146470464,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,28116,DB00080,10037660,34,606,66,847,0.141955718,0.720170678,0.455343242,1.121407687,0.272527191,DB0008010037660_,1.300016885,-0.328267042,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,daptomycin,DB00080
,28117,DB00250,10037660,40,786,43,767,0.735627971,0.907801009,0.56816551,1.447657827,0.847238699,DB0025010037660_,0.165772807,-0.096730077,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,dapsone,DB00250
,28118,DB00295,10037660,267,14396,202,9400,0.126998001,0.863078698,0.714804154,1.043322637,0.251460825,DB0029510037660_,1.380468068,-0.147249401,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,28119,DB00334,10037660,63,2786,64,2748,0.928538413,0.970946983,0.671787973,1.402869803,0.970269025,DB0033410037660_,0.0301819,-0.029483413,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,olanzapine,DB00334
,28122,DB01141,10037660,25,373,44,561,0.610754048,0.854705978,0.492236745,1.455535465,0.752880465,DB0114110037660_,0.283848808,-0.156997754,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,micafungin,DB01141
,28123,DB01413,10037660,93,1127,139,1520,0.488736477,0.902437188,0.678504464,1.195948525,0.652262546,DB0141310037660_,0.42730812,-0.102656189,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,cefepime,DB01413
,28125,DB00126,10000059,161,10010,70,5875,0.039216363,1.349875879,1.011463778,1.817160511,0.104053108,DB0012610000059_,2.262853861,0.300012647,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,28126,DB00158,10000059,237,16578,85,8019,0.019396603,1.348721808,1.046812137,1.751588709,0.060346774,DB0015810000059_,2.80764779,0.299157335,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,28127,DB01098,10000059,114,8035,95,7114,0.676090662,1.062467163,0.800489711,1.412762746,0.803737729,DB0109810000059_,0.218482271,0.060593716,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,28128,DB05676,10000059,2239,44890,1410,23919,1.9573876049607e-06,0.846123772,0.789755269,0.906736598,2.59782545803544e-05,DB0567610000059_,10.55825073,-0.167089628,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,28129,DB06724,10000059,140,7789,32,3887,2.72166114050027e-05,2.183163228,1.47499473,3.320633219,0.000260254,DB0672410000059_,8.253853056,0.780774847,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,28134,DB00158,10017885,115,16700,38,8066,0.04615862,1.461671614,1.00387815,2.170846219,0.117811266,DB0015810017885_,2.138671376,0.379580722,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,28135,DB01098,10017885,75,8074,40,7169,0.008631934,1.66477512,1.117978358,2.511767134,0.031653235,DB0109810017885_,3.452914917,0.509690051,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,28136,DB05676,10017885,318,46811,106,25223,1.05955500990041e-05,1.616468614,1.292824022,2.034558422,0.000114141,DB0567610017885_,9.078076052,0.480243902,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,28137,DB06724,10017885,132,7797,43,3876,0.015177345,1.525974716,1.071601484,2.210996022,0.049775766,DB0672410017885_,3.000227043,0.422633364,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,28138,DB00158,10038063,42,16773,38,8066,0.005685089,0.531503261,0.334231634,0.847785806,0.022672213,DB0015810038063_,3.786615208,-0.632045947,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,28139,DB01098,10038063,18,8131,34,7175,0.008068886,0.467185889,0.248162644,0.851619646,0.029994438,DB0109810038063_,3.506743298,-0.761028052,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,28142,DB00158,10047895,299,16516,172,7932,0.066093517,0.834893505,0.688402173,1.015089371,0.154320949,DB0015810047895_,1.868720759,-0.180451101,NA,10047895,Weight decreased,10022891,Investigations,Inv,folic acid,DB00158
,28143,DB06724,10047895,212,7717,95,3824,0.460865055,1.10579925,0.861247167,1.428381688,0.628213347,DB0672410047895_,0.464875446,0.100568377,NA,10047895,Weight decreased,10022891,Investigations,Inv,calcium carbonate,DB06724
,28145,DB00060,10013968,135,9373,23,2442,0.059990571,1.529164763,0.975256348,2.499996515,0.143461052,DB0006010013968_,1.941691697,0.42472168,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,interferon beta-1a,DB00060
,28147,DB00455,10013700,233,9168,67,5051,1.21567922121861e-06,1.91587013,1.450836465,2.558884564,1.70422017758566e-05,DB0045510013700_,10.97981783,0.650171896,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,loratadine,DB00455
,28148,DB00956,10013700,635,5179,141,3326,9.79906168251033e-34,2.891852211,2.392725007,3.514530436,2.7695520034923e-31,DB0095610013700_,70.36145231,1.0618972,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,hydrocodone,DB00956
,28166,DB00158,10011906,416,16399,471,7633,6.86988064885388e-38,0.411116379,0.358424678,0.471440048,2.50798351187672e-35,DB0015810011906_,79.67099921,-0.888878944,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,28167,DB00581,10011906,168,1945,206,1863,0.026184669,0.781200786,0.627031333,0.97227988,0.076152249,DB0058110011906_,2.57502066,-0.246923073,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,lactulose,DB00581
,28169,DB00112,10043554,119,5814,83,4008,0.942448558,0.988373298,0.73825094,1.328392913,0.981546095,DB0011210043554_,0.018626303,-0.011694821,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,bevacizumab,DB00112
,28170,DB00853,10061818,87,1734,133,2133,0.125729601,0.804697444,0.602296243,1.070717226,0.249673445,DB0085310061818_,1.387601435,-0.217288918,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,temozolomide,DB00853
,28172,DB00073,10002198,70,7336,54,6353,0.587528955,1.122571083,0.774584837,1.63464342,0.734585862,DB0007310002198_,0.308448392,0.115621664,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,rituximab,DB00073
,28174,DB00531,10002198,32,7220,21,6495,0.273449992,1.370761162,0.765524687,2.503818727,0.436434091,DB0053110002198_,0.829117909,0.315366178,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,cyclophosphamide,DB00531
,28176,DB00959,10002198,90,7988,59,4943,0.73513567,0.943941676,0.670906349,1.336638206,0.846926041,DB0095910002198_,0.166141907,-0.057690899,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,methylprednisolone,DB00959
,28179,DB00316,10013952,246,65228,100,36853,0.005030642,1.389864655,1.096812823,1.772289868,0.020564605,DB0031610013952_,3.884183872,0.329206372,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,28183,DB00863,10013952,57,10616,20,5820,0.094343058,1.562413337,0.923384735,2.748545067,0.202284631,DB0086310013952_,1.598079509,0.446231637,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,28184,DB00904,10013952,84,22985,39,14417,0.13737535,1.350957386,0.91304708,2.030160672,0.266064154,DB0090410013952_,1.324017819,0.300813516,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,28185,DB00959,10013952,34,8044,17,4985,0.564122542,1.239382598,0.672639132,2.36830363,0.715980735,DB0095910013952_,0.334102019,0.214613351,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,28187,DB01075,10013952,88,19860,41,11056,0.359204151,1.194825565,0.815232368,1.777180132,0.528990174,DB0107510013952_,0.636785423,0.178000204,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,28188,DB01234,10013952,153,31472,109,32779,0.002389081,1.461945505,1.135477303,1.887501814,0.011246889,DB0123410013952_,4.487663736,0.379768087,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,28189,DB00019,10021097,40,18972,30,9499,0.099456047,0.667572053,0.405220429,1.110696025,0.210052001,DB0001910021097_,1.560400154,-0.40410795,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,pegfilgrastim,DB00019
,28191,DB00635,10021097,454,32599,429,23365,4.89885324046812e-05,0.758520492,0.662514204,0.868501694,0.000434288,DB0063510021097_,7.741802918,-0.276385464,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,prednisone,DB00635
,28192,DB00959,10021097,137,7941,141,4861,2.05510357737253e-05,0.594822593,0.465362579,0.760037161,0.000204499,DB0095910021097_,8.494947719,-0.519492081,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,methylprednisolone,DB00959
,28193,DB00997,10021097,88,5243,98,3416,0.00034873,0.585108332,0.432253932,0.791036529,0.002287272,DB0099710021097_,6.080395401,-0.535958267,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,doxorubicin,DB00997
,28194,DB00863,10029331,118,10555,75,5765,0.32498798,0.859348374,0.636760274,1.165857505,0.493432825,DB0086310029331_,0.706368549,-0.151580882,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,28195,DB00959,10029331,80,7998,55,4947,0.593410235,0.899688756,0.629093423,1.294764733,0.739441928,DB0095910029331_,0.301859529,-0.105706403,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,28196,DB01075,10029331,163,19785,119,10978,0.024630849,0.760052145,0.595662882,0.972082597,0.072690942,DB0107510029331_,2.6215385,-0.274368237,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,28197,DB00019,10037844,103,18909,35,9494,0.046550395,1.477557117,0.997215288,2.236718975,0.118592404,DB0001910037844_,2.132062841,0.390390128,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,pegfilgrastim,DB00019
,28198,DB00377,10037844,65,1054,27,696,0.048786277,1.58933023,0.988848376,2.617636405,0.122771403,DB0037710037844_,2.097431165,0.463312688,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,palonosetron,DB00377
,28199,DB00531,10037844,133,7119,83,6433,0.008945133,1.447955574,1.090125958,1.932573214,0.032554215,DB0053110037844_,3.424848432,0.370152613,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cyclophosphamide,DB00531
,28200,DB00541,10037844,35,3099,39,4258,0.408066775,1.23302625,0.756520238,2.002875089,0.577475782,DB0054110037844_,0.549088773,0.209471513,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,vincristine,DB00541
,28201,DB00863,10037844,329,10344,162,5678,0.270820268,1.114784709,0.91814194,1.357833256,0.433513642,DB0086310037844_,0.835832014,0.1086613,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,28202,DB00904,10037844,672,22397,355,14101,0.008433601,1.191754541,1.044539753,1.361571518,0.031071162,DB0090410037844_,3.471475155,0.175426626,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,28203,DB00959,10037844,285,7793,155,4847,0.194641198,1.143641304,0.933892655,1.404606631,0.342556562,DB0095910037844_,1.07131849,0.134217299,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,methylprednisolone,DB00959
,28204,DB00997,10037844,73,5258,31,3483,0.043355682,1.559814561,1.009168931,2.462813866,0.11237591,DB0099710037844_,2.185905685,0.444566943,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,doxorubicin,DB00997
,28206,DB00316,10037855,111,65363,72,36881,0.356232578,0.869889917,0.640677727,1.187413415,0.525910489,DB0031610037855_,0.642624253,-0.139388608,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,28208,DB00381,10037855,53,29307,35,22852,0.519065882,1.180751711,0.755905734,1.865302756,0.678296801,DB0038110037855_,0.388170327,0.166151279,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,28213,DB01234,10037855,72,31553,61,32827,0.259243339,1.22797891,0.860610059,1.757113574,0.420357865,DB0123410037855_,0.866648871,0.205369656,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,28216,DB00316,10057371,57,65417,18,36935,0.030238625,1.7879166,1.036826087,3.228641292,0.085208218,DB0031610057371_,2.462657392,0.581051031,NA,10057371,Hypoaesthesia oral,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,28227,DB01234,10057371,40,31585,21,32867,0.010239414,1.982040219,1.140868544,3.539057811,0.036238455,DB0123410057371_,3.317634421,0.684126728,NA,10057371,Hypoaesthesia oral,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,28231,DB00381,10061284,52,29308,26,22861,0.067734072,1.560036304,0.956204413,2.60368683,0.157243548,DB0038110061284_,1.849959415,0.444709093,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,28235,DB00904,10061284,37,23032,21,14435,0.787899664,1.104264918,0.629407953,1.986352005,0.885095921,DB0090410061284_,0.122059255,0.099179881,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,28240,DB09072,10013700,97,6374,15,2520,0.000282325,2.556339395,1.472391068,4.752328544,0.001922267,DB0907210013700_,6.254250254,0.938576311,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,sodium oxybate,DB09072
,28241,DB00956,10037087,114,5700,61,3406,0.528356842,1.116727881,0.80874002,1.554690267,0.685783201,DB0095610037087_,0.377193734,0.110402875,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocodone,DB00956
,28245,DB00956,10053762,176,5638,77,3390,0.021091535,1.374302198,1.041825826,1.826846635,0.064478505,DB0095610053762_,2.741423371,0.31794611,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocodone,DB00956
,28247,DB00471,10011906,353,13836,202,5263,9.17832020962189e-06,0.6647464,0.555918327,0.796561086,0.000100774,DB0047110011906_,9.202626587,-0.408349664,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,28248,DB01261,10011906,142,3639,180,3123,0.000724079,0.677071336,0.536604074,0.853014359,0.004211179,DB0126110011906_,5.470012638,-0.389978641,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,28250,DB00363,10045555,18,4610,34,6854,0.479338994,0.787129506,0.417979445,1.435402234,0.644389487,DB0036310045555_,0.439451942,-0.239362487,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,clozapine,DB00363
,28252,DB00190,10012378,52,3245,51,4623,0.069443949,1.452489364,0.965229103,2.186789785,0.160306872,DB0019010012378_,1.83066535,0.373278887,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,28253,DB00370,10012378,138,4403,67,3596,0.00046887,1.68208416,1.243033848,2.294969969,0.00292703,DB0037010012378_,5.833766943,0.520033596,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,mirtazapine,DB00370
,28254,DB00051,10005750,88,25643,46,11374,0.398533712,0.848552123,0.587058641,1.240810297,0.568360839,DB0005110005750_,0.564998781,-0.164223766,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,adalimumab,DB00051
,28255,DB00051,10024855,98,25633,58,11362,0.082521361,0.748937969,0.535455919,1.055785285,0.182575972,DB0005110024855_,1.70058891,-0.289099118,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,28257,DB00480,10019211,809,66619,416,67246,2.85296224537801e-30,1.962992854,1.741053642,2.215843339,6.52087935824008e-28,DB0048010019211_,62.59737337,0.674470275,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,28258,DB00480,10047700,1027,66401,539,67123,3.61222006265921e-36,1.926076563,1.732779526,2.142920683,1.19430445719493e-33,DB0048010047700_,75.8077441,0.655485065,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,28264,DB00904,10024670,36,23033,32,14424,0.16983274,0.704536592,0.425157383,1.172270803,0.310704963,DB0090410024670_,1.168911488,-0.350215008,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,ondansetron,DB00904
,28265,DB08934,10037087,119,4370,119,6085,0.013829105,1.392382661,1.067473795,1.816131422,0.046098824,DB0893410037087_,3.076967841,0.331016425,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,sofosbuvir,DB08934
,28270,DB00215,10035528,72,11031,43,5233,0.231055668,0.794363387,0.536217005,1.189232332,0.387204223,DB0021510035528_,0.948803017,-0.230214256,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,citalopram,DB00215
,28378,DB00736,10013911,62,10529,27,5526,0.502086974,1.205138168,0.754500354,1.972620434,0.663444193,DB0073610013911_,0.410310539,0.186594223,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,28391,DB00060,10047895,114,9394,34,2431,0.474081984,0.867667757,0.585315349,1.316504325,0.63979283,DB0006010047895_,0.446610858,-0.141946406,NA,10047895,Weight decreased,10022891,Investigations,Inv,interferon beta-1a,DB00060
,28392,DB00381,10069327,134,29226,76,22811,0.025835161,1.37614123,1.030353555,1.849305112,0.075331655,DB0038110069327_,2.58585485,0.319283372,NA,10069327,Product quality issue,10077536,Product issues,Prod,amlodipine,DB00381
,28395,DB00555,10013700,214,6833,45,3441,1.38310554549196e-08,2.394660392,1.724535544,3.389592516,3.00826886746017e-07,DB0055510013700_,15.01673086,0.873241422,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,lamotrigine,DB00555
,28396,DB00795,10013700,781,3788,120,1383,1.23641362902508e-19,2.375905684,1.937904705,2.932391085,1.24279664393592e-17,DB0079510013700_,38.92658238,0.865378705,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,sulfasalazine,DB00795
,28399,DB00795,10025482,107,4462,21,1482,0.029209284,1.692108871,1.048339387,2.856098147,0.08295689,DB0079510025482_,2.489434202,0.525975604,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,28400,DB01611,10025482,412,11501,39,2322,1.15909955742435e-06,2.132727646,1.528437948,3.052489543,1.63230280562009e-05,DB0161110025482_,11.02293368,0.757401746,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,28405,DB00559,10023469,61,9598,16,3290,0.431014583,1.306807009,0.742760843,2.431979507,0.599429541,DB0055910023469_,0.511776841,0.267586764,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,bosentan,DB00559
,28406,DB08932,10023469,76,19367,13,6584,0.019806953,1.987521809,1.094654136,3.905354458,0.061315012,DB0893210023469_,2.791730565,0.68688854,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,28407,DB00377,10011906,433,686,320,403,0.019806249,0.795020838,0.654572958,0.965569845,0.061315012,DB0037710011906_,2.791730565,-0.229386954,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,palonosetron,DB00377
,28408,DB00073,10050584,59,7347,24,6383,0.001290122,2.135606279,1.306486324,3.594669507,0.00678353,DB0007310050584_,4.993257659,0.758750578,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,rituximab,DB00073
,28412,DB00635,10050584,358,32695,127,23667,6.95940461969004e-13,2.040482526,1.660817171,2.52026248,3.18412446350832e-11,DB0063510050584_,24.17025867,0.713186312,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,28415,DB00005,10052302,121,127961,68,42351,0.000708861,0.588931119,0.433964247,0.804917444,0.004137317,DB0000510052302_,5.487707712,-0.529446048,NA,10052302,Impaired work ability,10041244,Social circumstances,SocCi,etanercept,DB00005
,28418,DB08875,10011906,44,599,113,1130,0.095651505,0.734678806,0.49916842,1.065764669,0.204257032,DB0887510011906_,1.588376116,-0.308321874,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cabozantinib,DB08875
,28419,DB00480,10003549,1756,65672,1758,65904,0.945496739,1.002391062,0.936879765,1.072495502,0.984057881,DB0048010003549_,0.016070561,0.002388208,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,28420,DB00188,10010305,57,7829,60,8768,0.780673999,1.063905112,0.726222954,1.557194369,0.88062004,DB0018810010305_,0.127129028,0.061946206,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,bortezomib,DB00188
,28421,DB00188,10012174,167,7719,170,8658,0.378531373,1.101847143,0.882583928,1.375492659,0.548555362,DB0018810012174_,0.600467072,0.096987992,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,bortezomib,DB00188
,28429,DB00476,10009887,47,17210,18,6159,0.779326429,0.934444214,0.532115157,1.710874825,0.87977131,DB0047610009887_,0.12809328,-0.06780335,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,28439,DB00343,10038063,59,8677,28,5067,0.43524147,1.23050274,0.771050491,2.007027461,0.603657715,DB0034310038063_,0.504747939,0.207422818,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,28442,DB00635,10038063,66,32987,72,23722,0.015436748,0.6592224,0.46456352,0.934099143,0.050423128,DB0063510038063_,2.987305313,-0.416694321,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,28446,DB14513,10011906,182,6995,188,3376,1.22516603605029e-12,0.467254637,0.377372314,0.57846257,5.45359682600877e-11,DB1451310011906_,23.63216066,-0.760880908,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,28447,DB00222,10005557,113,3093,98,3030,0.401222291,1.129552701,0.849975936,1.503185371,0.571048729,DB0022210005557_,0.560280733,0.121821715,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,glimepiride,DB00222
,28449,DB08907,10012671,450,3803,381,3529,0.213161271,1.095977751,0.946691371,1.269314161,0.365210853,DB0890710012671_,1.007280413,0.091646888,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,canagliflozin,DB08907
,28450,DB01164,10005734,43,6481,54,7882,0.918669074,0.968429733,0.632408033,1.475020614,0.964056956,DB0116410005734_,0.036604903,-0.032079351,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,calcium chloride,DB01164
,28454,DB00281,10000060,86,11372,31,5640,0.139505166,1.375866331,0.901673258,2.149646076,0.269119907,DB0028110000060_,1.312598249,0.319083592,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,28455,DB00295,10000060,57,14606,51,9551,0.114480519,0.730863956,0.491594901,1.089084357,0.232851482,DB0029510000060_,1.457354443,-0.313527943,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,28456,DB00316,10000060,446,65028,189,36764,0.000898715,1.334117901,1.122358827,1.590867094,0.005045972,DB0031610000060_,5.289165041,0.288270325,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,28457,DB00327,10000060,44,6094,30,4232,1,1.018531061,0.624901733,1.680947376,1,DB0032710000060_,0,0.018361453,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,hydromorphone,DB00327
,28459,DB00557,10000060,45,5942,14,3053,0.128041697,1.651416532,0.888477105,3.263084468,0.252881206,DB0055710000060_,1.374835443,0.501633424,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,hydroxyzine,DB00557
,28461,DB00641,10000060,91,14033,69,12406,0.341823508,1.165925549,0.842500133,1.619778145,0.511038928,DB0064110000060_,0.671309512,0.153515234,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,28462,DB00646,10000060,31,3422,22,1978,0.47603374,0.814531243,0.455244152,1.480874829,0.641455252,DB0064610000060_,0.444015853,-0.205142493,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,nystatin,DB00646
,28466,DB00736,10000060,109,10482,43,5510,0.122524254,1.332486124,0.92660438,1.946341879,0.24505783,DB0073610000060_,1.406261055,0.287046463,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,28467,DB00813,10000060,44,10528,41,10127,0.913747477,1.032300113,0.658480367,1.621466944,0.961391243,DB0081310000060_,0.039373832,0.031789432,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,28469,DB00863,10000060,98,10575,47,5793,0.486062694,1.142202862,0.79750228,1.65616508,0.649960453,DB0086310000060_,0.430843759,0.132958733,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,28470,DB00864,10000060,41,6828,24,8368,0.003851875,2.093552029,1.233911447,3.626311357,0.016544904,DB0086410000060_,4.101677152,0.738862159,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,28471,DB00904,10000060,219,22850,87,14369,0.000244224,1.582923198,1.228147407,2.055136243,0.00170051,DB0090410000060_,6.376826912,0.459273263,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,28473,DB00959,10000060,49,8029,22,4980,0.222703599,1.38143651,0.818447191,2.402572623,0.376835593,DB0095910000060_,0.975946281,0.323123907,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,28475,DB01075,10000060,154,19794,62,11035,0.032396709,1.384724676,1.023775115,1.892650723,0.089958535,DB0107510000060_,2.40840644,0.32550133,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,28476,DB01109,10000060,33,4379,25,4245,0.360284404,1.279568218,0.736656346,2.24844709,0.530165181,DB0110910000060_,0.634566658,0.246522691,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,heparin,DB01109
,28478,DB01137,10000060,32,7740,34,5559,0.13283667,0.67600213,0.403344849,1.130559874,0.259724913,DB0113710000060_,1.348132233,-0.391559052,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,28479,DB01202,10000060,30,6684,22,5696,0.676343454,1.162055074,0.647447476,2.116782206,0.80384645,DB0120210000060_,0.21834701,0.150190053,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,levetiracetam,DB01202
,28485,DB11089,10000060,102,10073,72,8335,0.320423968,1.172223884,0.857179268,1.610242431,0.488605888,DB1108910000060_,0.716199069,0.1589027,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,28486,DB00016,10012735,163,2599,105,2185,0.043454943,1.305028973,1.007921796,1.695554211,0.112549952,DB0001610012735_,2.184358137,0.266225242,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,erythropoietin,DB00016
,28487,DB00281,10012735,429,11029,186,5485,0.126879431,1.147035955,0.96041963,1.374150977,0.25128284,DB0028110012735_,1.381176121,0.137181184,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,28489,DB00557,10012735,306,5681,108,2959,0.000538523,1.475707371,1.175616416,1.863707026,0.003280816,DB0055710012735_,5.719662976,0.389137448,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,hydroxyzine,DB00557
,28491,DB00646,10012735,255,3198,111,1889,0.009712602,1.356897683,1.073346504,1.723964784,0.03477433,DB0064610012735_,3.358875822,0.305200979,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,nystatin,DB00646
,28492,DB00653,10012735,66,1026,39,783,0.225338549,1.29132732,0.846192865,1.993209601,0.380180607,DB0065310012735_,0.967108857,0.255670619,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,magnesium sulfate,DB00653
,28495,DB00736,10012735,621,9970,247,5306,0.000131791,1.338009512,1.148225155,1.56284293,0.001009303,DB0073610012735_,6.898494991,0.291183071,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,28497,DB00864,10012735,387,6482,367,8025,0.000411127,1.305479177,1.124500647,1.515842652,0.002621023,DB0086410012735_,5.944190639,0.266570158,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,28499,DB01012,10012735,256,10376,172,8513,0.049262941,1.221123006,1.00042476,1.493505738,0.123609986,DB0101210012735_,2.090623942,0.199770932,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cinacalcet,DB01012
,28500,DB01109,10012735,146,4266,88,4182,0.000332168,1.626323104,1.235303276,2.151390023,0.002194276,DB0110910012735_,6.121903236,0.486321702,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,heparin,DB01109
,28502,DB01137,10012735,364,7408,220,5373,0.039441437,1.200020187,1.008422611,1.430543609,0.104528954,DB0113710012735_,2.25829117,0.182338379,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,28503,DB01233,10012735,172,3249,95,1631,0.464721976,0.90890509,0.698172613,1.18892635,0.631718105,DB0123310012735_,0.459312021,-0.095514602,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,metoclopramide,DB01233
,28505,DB01390,10012735,96,1313,78,1439,0.060461611,1.348731798,0.980216961,1.860422734,0.14423974,DB0139010012735_,1.936278504,0.299164742,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sodium bicarbonate,DB01390
,28507,DB01610,10012735,59,882,66,1152,0.404624632,1.167506481,0.798346538,1.704125566,0.574382764,DB0161010012735_,0.554459269,0.154870262,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,valganciclovir,DB01610
,28525,DB00904,10021027,76,22993,28,14428,0.015247774,1.703177059,1.090538925,2.730683486,0.049948622,DB0090410021027_,2.99676037,0.532495365,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,28529,DB01075,10021027,51,19897,7,11090,8.5790777432945e-05,4.060694053,1.83409536,10.61263552,0.000699956,DB0107510021027_,7.264493243,1.401353908,female,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,diphenhydramine,DB01075
,28540,DB00281,10021036,36,11422,30,5641,0.036210624,0.592649963,0.354507017,0.997368793,0.097953412,DB0028110021036_,2.323263298,-0.523151337,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,lidocaine,DB00281
,28541,DB00295,10021036,43,14620,35,9567,0.354637885,0.803965026,0.502214187,1.295100654,0.524469396,DB0029510021036_,0.645368202,-0.218199511,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,morphine,DB00295
,28549,DB00813,10021036,26,10546,31,10137,0.429398134,0.806192667,0.45942734,1.404218912,0.597877421,DB0081310021036_,0.514369528,-0.215432523,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,fentanyl,DB00813
,28552,DB00864,10021036,38,6831,18,8374,0.000665804,2.587824221,1.439646595,4.821684159,0.003931848,DB0086410021036_,5.538645624,0.950817453,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,tacrolimus,DB00864
,28556,DB01075,10021036,59,19889,31,11066,0.826669757,1.058934315,0.673978787,1.693640042,0.908584167,DB0107510021036_,0.095867751,0.057263039,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,diphenhydramine,DB01075
,28559,DB01137,10021036,42,7730,40,5553,0.217403071,0.754313663,0.476720944,1.195140916,0.370361643,DB0113710021036_,0.993275337,-0.281946999,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,levofloxacin,DB01137
,28560,DB01202,10021036,33,6681,29,5689,0.899233916,0.968962317,0.569626353,1.656477523,0.956490275,DB0120210021036_,0.044484657,-0.031529556,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,levetiracetam,DB01202
,28561,DB01233,10021036,35,3386,20,1706,0.667912454,0.881746256,0.493386953,1.617141866,0.798275724,DB0123310021036_,0.225301222,-0.125850956,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,metoclopramide,DB01233
,28566,DB00016,10028813,171,2591,84,2206,4.42535152889888e-05,1.733036759,1.318341982,2.292413723,0.000398229,DB0001610028813_,7.82848292,0.549875222,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,erythropoietin,DB00016
,28567,DB00281,10028813,659,10799,223,5448,2.54676576046605e-07,1.49081774,1.274268345,1.749359567,4.21547468601072e-06,DB0028110028813_,12.37674835,0.399324788,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,28570,DB00646,10028813,250,3203,94,1906,0.00016714,1.582498535,1.234617147,2.041967045,0.001238237,DB0064610028813_,6.694066628,0.45900495,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,nystatin,DB00646
,28571,DB00653,10028813,77,1015,51,771,0.517817497,1.146762243,0.784193476,1.688806405,0.677307503,DB0065310028813_,0.389629896,0.136942531,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,magnesium sulfate,DB00653
,28572,DB00683,10028813,52,1532,34,1604,0.037580979,1.601046191,1.013183411,2.559545163,0.100746154,DB0068310028813_,2.295151257,0.470657285,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,midazolam,DB00683
,28574,DB00818,10028813,38,1382,19,1658,0.001814091,2.3987684,1.341824316,4.426484144,0.00897823,DB0081810028813_,4.71295254,0.874955439,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,propofol,DB00818
,28575,DB00864,10028813,301,6568,228,8164,3.03693640237732e-08,1.640893186,1.372539705,1.96377489,6.12866589915454e-07,DB0086410028813_,14.30511856,0.495240719,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,28577,DB01109,10028813,324,4088,126,4144,6.77139805104554e-21,2.606382635,2.105125385,3.242781602,7.84080166395295e-19,DB0110910028813_,41.68977568,0.957963296,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,heparin,DB01109
,28579,DB01327,10028813,35,628,34,723,0.536992493,1.184989917,0.708459125,1.983940543,0.69321397,DB0132710028813_,0.366416568,0.169734266,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cefazolin,DB01327
,28580,DB01390,10028813,74,1335,55,1462,0.037879432,1.473242012,1.016664257,2.145701965,0.101411782,DB0139010028813_,2.288565997,0.387465423,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sodium bicarbonate,DB01390
,28582,DB01610,10028813,55,886,45,1173,0.022710208,1.617735414,1.060025584,2.479939139,0.068221464,DB0161010028813_,2.684996041,0.481027279,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,valganciclovir,DB01610
,28583,DB00016,10037087,64,2698,35,2255,0.052263362,1.528199427,0.992684067,2.387394837,0.129275158,DB0001610037087_,2.045812137,0.424090197,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,erythropoietin,DB00016
,28584,DB00295,10037087,408,14255,154,9448,1.10510355219015e-09,1.755907341,1.452500901,2.131496843,3.04323173067763e-08,DB0029510037087_,17.30776072,0.562985727,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,morphine,DB00295
,28585,DB00327,10037087,153,5985,51,4211,1.72946192388785e-06,2.11062327,1.523968366,2.964969175,2.33003109530457e-05,DB0032710037087_,10.66704385,0.746983292,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,hydromorphone,DB00327
,28587,DB00557,10037087,272,5715,87,2980,6.44851784607775e-05,1.630151404,1.270423866,2.108718244,0.000547478,DB0055710037087_,7.510187673,0.488672897,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxyzine,DB00557
,28589,DB00641,10037087,271,13853,158,12317,2.58838497976387e-05,1.524983265,1.246779212,1.870407394,0.00024885,DB0064110037087_,8.298658648,0.421983436,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,28590,DB00646,10037087,59,3394,42,1958,0.299448269,0.81045102,0.534149386,1.239175017,0.465450327,DB0064610037087_,0.764749898,-0.210164371,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,nystatin,DB00646
,28594,DB00813,10037087,148,10424,47,10121,1.00556403937003e-12,3.057488581,2.185626105,4.34565863,4.51430414600193e-11,DB0081310037087_,23.82118497,1.117593854,female,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,fentanyl,DB00813
,28596,DB00863,10037087,282,10391,94,5746,1.51997403357683e-05,1.658887918,1.305957756,2.122955508,0.000156738,DB0086310037087_,8.760934905,0.506147449,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,28597,DB00864,10037087,87,6782,51,8341,2.1689515207834e-05,2.097936533,1.465702585,3.029987192,0.000214045,DB0086410037087_,8.449324197,0.740954258,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,tacrolimus,DB00864
,28599,DB00959,10037087,281,7797,89,4913,5.04017265285127e-09,1.989360279,1.557555888,2.561262261,1.20821649047146e-07,DB0095910037087_,15.92895035,0.687813119,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,methylprednisolone,DB00959
,28600,DB01012,10037087,88,10544,71,8614,1,1.012567119,0.731236189,1.406299261,1,DB0101210037087_,0,0.012488808,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,cinacalcet,DB01012
,28602,DB01137,10037087,127,7645,60,5533,0.007054497,1.531869758,1.115937318,2.123078834,0.026953008,DB0113710037087_,3.613660359,0.426489053,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,levofloxacin,DB01137
,28607,DB00281,10037660,325,11133,164,5507,0.845453659,0.980251283,0.807635127,1.193429489,0.922144049,DB0028110037660_,0.081053832,-0.019946329,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,28610,DB00641,10037660,175,13949,234,12241,2.63132837574277e-05,0.656307202,0.535599272,0.802987413,0.000252379,DB0064110037660_,8.284578612,-0.421126304,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,28611,DB00683,10037660,32,1552,40,1598,0.474858661,0.823761946,0.498078561,1.352619723,0.640497571,DB0068310037660_,0.445509949,-0.193873692,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,midazolam,DB00683
,28613,DB00736,10037660,199,10392,104,5449,1,1.003315044,0.785677354,1.28742924,1,DB0073610037660_,0,0.003309561,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,28614,DB00813,10037660,190,10382,132,10036,0.004105337,1.391396221,1.106480007,1.753957872,0.017446161,DB0081310037660_,4.048635639,0.330307719,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,28617,DB01109,10037660,144,4268,154,4116,0.409196935,0.901774802,0.710471209,1.144061921,0.578607856,DB0110910037660_,0.547130309,-0.103390456,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,28619,DB01233,10037660,102,3319,65,1661,0.134502742,0.785384594,0.566454996,1.095430453,0.261959438,DB0123310037660_,1.339565603,-0.241581753,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,28620,DB01327,10037660,21,642,44,713,0.021388667,0.530284756,0.296114051,0.922454364,0.065203589,DB0132710037660_,2.730240773,-0.634341142,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,cefazolin,DB01327
,28621,DB01390,10037660,39,1370,50,1467,0.451245778,0.835278338,0.531401064,1.304628895,0.618920646,DB0139010037660_,0.479778211,-0.179990271,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sodium bicarbonate,DB01390
,28623,DB01610,10037660,55,886,71,1147,1,1.002844315,0.684263027,1.463382975,1,DB0161010037660_,0,0.002840277,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,valganciclovir,DB01610
,28629,DB00557,10037884,44,5943,12,3055,0.048278927,1.884733031,0.976725117,3.92635532,0.121850459,DB0055710037884_,2.104960734,0.633786183,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxyzine,DB00557
,28637,DB00863,10037884,51,10622,28,5812,1,0.996624142,0.615931515,1.643373769,1,DB0086310037884_,0,-0.003381569,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,28640,DB00959,10037884,44,8034,21,4981,0.37130183,1.299001552,0.755027069,2.30285921,0.540956606,DB0095910037884_,0.614416213,0.261595933,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,methylprednisolone,DB00959
,28650,DB11089,10037884,40,10135,28,8379,0.542930917,1.181044692,0.71003342,1.98962267,0.698118538,DB1108910037884_,0.359366365,0.166399379,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,docusate,DB11089
,28654,DB00316,10043882,173,65301,82,36871,0.214716525,1.191203667,0.910484243,1.569328373,0.367077975,DB0031610043882_,1.002180989,0.174964281,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,acetaminophen,DB00316
,28659,DB00641,10043882,37,14087,28,12447,0.619053029,1.167581245,0.694984512,1.981949098,0.75997426,DB0064110043882_,0.274470715,0.154934297,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,simvastatin,DB00641
,28669,DB00904,10043882,53,23016,23,14433,0.157068107,1.445009115,0.869976074,2.471429181,0.293574286,DB0090410043882_,1.225624568,0.36811563,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,ondansetron,DB00904
,28673,DB01075,10043882,38,19910,21,11076,1,1.006644034,0.57561067,1.806379707,1,DB0107510043882_,0,0.006622059,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,diphenhydramine,DB01075
,28687,DB00316,10047281,46,65428,15,36938,0.062913566,1.731306225,0.949105397,3.339274271,0.148801664,DB0031610047281_,1.905140975,0.548876167,NA,10047281,Ventricular arrhythmia,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,28717,DB00281,10047700,398,11060,121,5550,9.71492161436576e-07,1.650531534,1.339746013,2.045427053,1.39430960659213e-05,DB0028110047700_,11.18052608,0.501097378,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,28719,DB00557,10047700,247,5740,69,2998,2.14775229038412e-06,1.869564419,1.420645508,2.487539613,2.82268344763732e-05,DB0055710047700_,10.47523746,0.625705473,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,hydroxyzine,DB00557
,28721,DB00646,10047700,135,3318,66,1934,0.263893062,1.192177121,0.87671219,1.63450133,0.425756761,DB0064610047700_,0.85388708,0.175781149,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,nystatin,DB00646
,28722,DB00653,10047700,73,1019,32,790,0.008234484,1.768080183,1.13868801,2.799179194,0.03048965,DB0065310047700_,3.490367993,0.569894315,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,magnesium sulfate,DB00653
,28723,DB00683,10047700,49,1535,29,1609,0.015893535,1.770787684,1.090208977,2.923432183,0.051578686,DB0068310047700_,2.964646762,0.571424467,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,midazolam,DB00683
,28726,DB00864,10047700,201,6668,166,8226,0.000157764,1.493701814,1.206905304,1.850703186,0.001178074,DB0086410047700_,6.743874667,0.401257478,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,28728,DB00959,10047700,261,7817,105,4897,0.000128062,1.557137502,1.233163481,1.977814848,0.000984684,DB0095910047700_,6.923189364,0.442849201,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,28729,DB01109,10047700,205,4207,104,4166,2.17899401981486e-08,1.951785496,1.527828734,2.505609383,4.53482642999474e-07,DB0110910047700_,14.60630884,0.668744593,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,heparin,DB01109
,28731,DB01137,10047700,227,7545,128,5465,0.025381411,1.284513147,1.026758546,1.612622828,0.074338447,DB0113710047700_,2.599126999,0.250379773,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,28734,DB01610,10047700,46,895,36,1182,0.022898306,1.687074327,1.057153751,2.710977711,0.068660961,DB0161010047700_,2.678574499,0.522995861,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,valganciclovir,DB01610
,28742,DB00641,10047943,38,14086,21,12454,0.089923237,1.599840043,0.914811832,2.871049751,0.195096249,DB0064110047943_,1.63426226,0.469903651,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,simvastatin,DB00641
,28752,DB00904,10047943,82,22987,48,14408,0.786639738,1.070771554,0.740433131,1.563523351,0.884260501,DB0090410047943_,0.123003576,0.068379467,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,ondansetron,DB00904
,28756,DB01075,10047943,45,19903,25,11072,1,1.001336441,0.600644132,1.705028654,1,DB0107510047943_,0,0.001335549,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,diphenhydramine,DB01075
,28764,DB11089,10047943,39,10136,20,8387,0.088764341,1.613477105,0.917643881,2.922214292,0.193203264,DB1108910047943_,1.644012464,0.478391543,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,docusate,DB11089
,28781,DB00864,10055181,70,6799,111,8281,0.09800661,0.768105241,0.560202948,1.047185796,0.207884422,DB0086410055181_,1.570773019,-0.263828523,NA,10055181,BK virus infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,28829,DB00281,10003988,231,11227,101,5570,0.316865605,1.13468629,0.892228013,1.451451664,0.484684149,DB0028110003988_,0.724257839,0.126356216,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lidocaine,DB00281
,28830,DB00281,10008469,73,11385,24,5647,0.083815382,1.508643697,0.93873346,2.505371175,0.184776257,DB0028110008469_,1.688609608,0.411211033,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,28831,DB00281,10008479,168,11290,97,5574,0.236352994,0.855105058,0.660613115,1.11192978,0.393584613,DB0028110008479_,0.932459207,-0.156530943,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,28832,DB00281,10013968,403,11055,188,5483,0.505031488,1.063180058,0.889157025,1.274896625,0.665985333,DB0028110013968_,0.406487631,0.061264472,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,28833,DB00281,10020937,128,11330,32,5639,0.000267909,1.990750229,1.340497765,3.036015608,0.00184008,DB0028110020937_,6.297946209,0.688511567,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,28835,DB00281,10033425,208,11250,55,5616,1.57400016008398e-05,1.887820946,1.393805252,2.594231894,0.00016158,DB0028110033425_,8.730509331,0.635423225,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,lidocaine,DB00281
,28836,DB00281,10037844,237,11221,116,5555,0.954462993,1.011445836,0.804666866,1.277190798,0.992309296,DB0028110037844_,0.00772043,0.011380828,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,lidocaine,DB00281
,28837,DB00281,10053762,363,11095,158,5513,0.185546399,1.141571425,0.941718802,1.388872095,0.330885518,DB0028110053762_,1.10598283,0.132405756,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lidocaine,DB00281
,28838,DB01306,10012671,123,4085,71,3795,0.00169447,1.609309014,1.187784498,2.194422378,0.00848284,DB0130610012671_,4.769709926,0.475804903,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,insulin aspart,DB01306
,28839,DB01306,10020993,89,4119,132,3734,0.000370874,0.611264607,0.460077064,0.808964187,0.002406721,DB0130610020993_,6.029490072,-0.492225342,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,insulin aspart,DB01306
,28841,DB01306,10069327,68,4140,53,3813,0.409451602,1.18165368,0.810636637,1.730461535,0.578858968,DB0130610069327_,0.546696409,0.166914881,NA,10069327,Product quality issue,10077536,Product issues,Prod,insulin aspart,DB01306
,28844,DB00316,10000880,46,65428,44,36909,0.015202329,0.589731023,0.381464667,0.912899267,0.049840126,DB0031610000880_,2.99893488,-0.528088739,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,28846,DB00928,10000880,42,793,49,1237,0.188698072,1.336843664,0.854997161,2.082588848,0.334915347,DB0092810000880_,1.093877475,0.290311361,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,azacitidine,DB00928
,28848,DB00455,10006002,72,9329,28,5090,0.14168399,1.402967248,0.893881722,2.2584514,0.272108997,DB0045510006002_,1.301552567,0.338589456,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,28853,DB01088,10025482,106,1323,20,417,0.038514208,1.670170014,1.013644119,2.881013679,0.102672005,DB0108810025482_,2.276215791,0.512925426,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,iloprost,DB01088
,28860,DB01268,10033371,119,2024,135,2995,0.042309555,1.304281252,1.003990972,1.692721841,0.110321959,DB0126810033371_,2.204352285,0.265652125,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,28861,DB01268,10042128,174,1969,180,2950,0.000926032,1.448142239,1.159625863,1.808230613,0.005171179,DB0126810042128_,5.264654582,0.37028152,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,28862,DB00338,10018100,34,33640,21,22251,0.890711852,1.070919559,0.603720919,1.942340309,0.954671384,DB0033810018100_,0.046388098,0.06851768,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,28869,DB00927,10009033,47,7450,29,4987,0.814626323,1.084891273,0.667764342,1.790075359,0.900576019,DB0092710009033_,0.104720699,0.081479772,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,28870,DB01068,10009033,80,13683,29,6811,0.154051513,1.373157678,0.8867524,2.18101342,0.289614421,DB0106810009033_,1.239204825,0.317112962,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,28874,DB01164,10003658,35,6489,43,7893,1,0.990065705,0.614315037,1.585784833,1,DB0116410003658_,0,-0.009983969,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,calcium chloride,DB01164
,28875,DB00264,10045555,96,29511,91,24801,0.419400661,0.886577123,0.658212893,1.19491135,0.588414538,DB0026410045555_,0.530323583,-0.12038716,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,28877,DB01164,10047895,40,6484,66,7870,0.141647317,0.735626728,0.48313815,1.107524595,0.272074224,DB0116410047895_,1.301680366,-0.307032452,NA,10047895,Weight decreased,10022891,Investigations,Inv,calcium chloride,DB01164
,28878,DB00264,10054236,90,29517,51,24841,0.027410948,1.485132149,1.041463823,2.137989565,0.078906667,DB0026410054236_,2.53948956,0.395503757,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,28879,DB00695,10005557,203,27846,172,20356,0.156898353,0.862779441,0.700116935,1.064216041,0.293326507,DB0069510005557_,1.226468932,-0.147596193,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,furosemide,DB00695
,28880,DB00722,10005557,244,25159,234,25798,0.490654253,1.069251642,0.889222443,1.285922101,0.653898852,DB0072210005557_,0.424802601,0.066959004,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,lisinopril,DB00722
,28882,DB00480,10020772,327,67101,202,67460,4.49263608999688e-08,1.627456842,1.36100745,1.949855921,8.76030709388487e-07,DB0048010020772_,13.94786469,0.487018577,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,lenalidomide,DB00480
,28883,DB00874,10020772,51,3284,21,1955,0.177275459,1.445658874,0.851210823,2.538514592,0.320351302,DB0087410020772_,1.138337067,0.368565186,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,guaifenesin,DB00874
,28884,DB01136,10020772,206,9678,147,10968,2.02143937512578e-05,1.588099251,1.276636583,1.979598771,0.000201569,DB0113610020772_,8.509379828,0.462537861,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,carvedilol,DB01136
,28885,DB00316,10033557,426,65048,96,36857,9.3600388891741e-19,2.514318182,2.009708608,3.172387428,8.66297965499793e-17,DB0031610033557_,36.98488785,0.922001666,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,28886,DB00331,10033557,187,24759,54,20698,1.35186364346951e-13,2.894770839,2.126901407,3.997433505,6.79421335919617e-12,DB0033110033557_,25.71494984,1.06290595,female,10033557,Palpitations,10007541,Cardiac disorders,Card,metformin,DB00331
,28887,DB00480,10033557,155,67273,60,67602,4.461193007936e-11,2.596082182,1.914779118,3.558840637,1.5459783548266e-09,DB0048010033557_,20.28760889,0.954003456,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,28888,DB00695,10033557,386,27663,83,20445,4.80023137909683e-30,3.437011257,2.703010963,4.414967064,1.06927187965729e-27,DB0069510033557_,62.10281958,1.234602273,female,10033557,Palpitations,10007541,Cardiac disorders,Card,furosemide,DB00695
,28889,DB00722,10033557,164,25239,70,25962,1.76440994786278e-10,2.410020685,1.809907806,3.237327983,5.54754969851355e-09,DB0072210033557_,19.0099095,0.879635331,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,lisinopril,DB00722
,28891,DB01136,10033557,88,9796,38,11077,3.43144397366818e-07,2.618511764,1.768775745,3.942503418,5.51485813805369e-06,DB0113610033557_,12.10806463,0.962606127,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,carvedilol,DB01136
,28892,DB00331,10043607,131,24815,136,20616,0.073790819,0.800251662,0.624219277,1.025625156,0.167871878,DB0033110043607_,1.78455422,-0.222829024,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,metformin,DB00331
,28897,DB00181,10035669,42,9814,44,5827,0.009818906,0.566801938,0.361864387,0.88658674,0.035054662,DB0018110035669_,3.350846651,-0.567745351,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,baclofen,DB00181
,28904,DB00973,10005425,50,3801,39,2982,1,1.005807482,0.646587487,1.574789497,1,DB0097310005425_,0,0.005790684,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,ezetimibe,DB00973
,28907,DB01362,10041232,64,802,41,549,0.83660334,1.068513743,0.699367087,1.647787738,0.915625842,DB0136210041232_,0.088147467,0.066268658,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iohexol,DB01362
,28909,DB09065,10047700,23,729,52,1885,0.602672752,1.143615609,0.662883044,1.918187262,0.746535806,DB0906510047700_,0.292311697,0.13419483,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cobicistat,DB09065
,28918,DB01073,10066260,29,1036,30,1620,0.137559742,1.511299489,0.869672176,2.622998038,0.266287989,DB0107310066260_,1.323176891,0.412969869,NA,10066260,Acute graft versus host disease,10021428,Immune system disorders,Immun,fludarabine,DB01073
,28920,DB00005,10049551,102,127980,42,42377,0.247007247,0.804145633,0.556125983,1.181258578,0.406142103,DB0000510049551_,0.901052174,-0.217974891,NA,10049551,Shoulder arthroplasty,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,28924,DB00635,10028391,257,32796,122,23672,0.000130841,1.520490729,1.220207319,1.903342424,0.001002965,DB0063510028391_,6.904794764,0.419033131,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,28925,DB00005,10069327,76,128006,51,42368,0.00018386,0.493214545,0.341364227,0.717866765,0.00134355,DB0000510069327_,6.612440116,-0.706811016,NA,10069327,Product quality issue,10077536,Product issues,Prod,etanercept,DB00005
,28933,DB00203,10067671,40,13838,17,8921,0.1743733,1.516852979,0.840052826,2.855340928,0.316598894,DB0020310067671_,1.150119624,0.41663778,NA,10067671,Disease complication,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,28934,DB00559,10067671,50,9609,21,3285,0.415136162,0.813964426,0.479218399,1.429062136,0.584365341,DB0055910067671_,0.537228908,-0.205838617,NA,10067671,Disease complication,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,28939,DB00588,10022116,73,16451,11,8457,2.31709523332609e-05,3.411437755,1.797731758,7.136790943,0.000226581,DB0058810022116_,8.392410107,1.227133831,female,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,28941,DB00904,10022116,319,22750,102,14354,4.49903703735521e-10,1.973211983,1.572476873,2.493417021,1.32947935387163e-08,DB0090410022116_,18.13589334,0.679662663,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,28944,DB00804,10033371,173,2827,27,872,0.000726381,1.976177727,1.301298874,3.107141617,0.004220576,DB0080410033371_,5.46778363,0.681164538,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,dicyclomine,DB00804
,28945,DB13867,10033371,181,4369,73,2481,0.016357852,1.407928067,1.062063902,1.882450966,0.052717772,DB1386710033371_,2.94280265,0.342119168,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,28953,DB00904,10049119,297,22772,55,14401,5.81417169589046e-21,3.414847965,2.551660475,4.644124409,6.74726282677619e-19,DB0090410049119_,41.83997985,1.228132972,female,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,28960,DB00455,10013950,59,9342,31,5087,0.912311306,1.036362835,0.659086523,1.658850472,0.960594091,DB0045510013950_,0.040203341,0.035717309,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,28961,DB00471,10013950,92,14097,26,5439,0.180479153,1.365176529,0.874142279,2.201551577,0.324424314,DB0047110013950_,1.125703008,0.311283745,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,28962,DB00567,10013950,38,4481,20,2061,0.670526643,0.873916217,0.494470842,1.58931038,0.800108626,DB0056710013950_,0.223007778,-0.134770769,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,cephalexin,DB00567
,28966,DB00455,10042128,67,9334,19,5099,0.009230667,1.926285533,1.141774746,3.39994357,0.033387653,DB0045510042128_,3.399569115,0.655593554,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,28967,DB00471,10042128,57,14132,9,5456,0.008572932,2.444934478,1.200667794,5.622094406,0.031473602,DB0047110042128_,3.458606106,0.894018324,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,28972,DB00455,10043521,46,9355,19,5099,0.3629097,1.319597256,0.75712598,2.387565662,0.532418803,DB0045510043521_,0.630324877,0.277326581,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,28973,DB00471,10043521,72,14117,22,5443,0.419012941,1.261813432,0.772629194,2.139041694,0.5880746,DB0047110043521_,0.530901468,0.232549918,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,28990,DB06643,10000087,208,52213,21,7494,0.133708249,1.421597377,0.905236028,2.347016988,0.260924408,DB0664310000087_,1.343524538,0.351781153,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,28992,DB06643,10008531,167,52254,31,7484,0.196038148,0.771563618,0.523060171,1.172569905,0.344304606,DB0664310008531_,1.066228531,-0.259336151,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,28993,DB06643,10010305,90,52331,30,7485,0.00024651,0.429103873,0.280844112,0.672637985,0.001714838,DB0664310010305_,6.36843684,-0.84605626,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,denosumab,DB06643
,28995,DB06643,10016766,78,52343,13,7502,0.633315084,0.859955262,0.474451918,1.687637351,0.771948665,DB0664310016766_,0.258837227,-0.150874913,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,28996,DB06643,10017944,114,52307,13,7502,0.503514815,1.257696077,0.706351491,2.435518627,0.664652199,DB0664310017944_,0.408491384,0.229281537,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,28997,DB06643,10022437,297,52124,59,7456,0.024451084,0.720073049,0.542379981,0.97014653,0.072298412,DB0664310022437_,2.626953115,-0.328402615,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,denosumab,DB06643
,28998,DB06643,10033425,1612,50809,101,7414,3.20884235742968e-20,2.328907971,1.900842505,2.880764466,3.37377685460157e-18,DB0664310033425_,40.23049883,0.845399476,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,28999,DB06643,10033557,82,52339,8,7507,0.342316529,1.470151815,0.71169888,3.52058934,0.51163051,DB0664310033557_,0.670152576,0.385365671,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,denosumab,DB06643
,29001,DB06643,10044565,115,52306,26,7489,0.040923287,0.633291533,0.410602849,1.010964247,0.107496987,DB0664310044565_,2.230292458,-0.456824406,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,29002,DB06643,10047571,77,52344,7,7508,0.321073158,1.577781681,0.729775859,4.057128226,0.489354514,DB0664310047571_,0.714668075,0.456019861,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,denosumab,DB06643
,29003,DB00916,10013709,237,5086,141,2290,0.012294095,0.75681571,0.608117485,0.944611722,0.041962119,DB0091610013709_,3.170987991,-0.278635503,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,29012,DB00864,10033371,81,6788,60,8332,0.003687523,1.656992034,1.170163607,2.357534489,0.015981294,DB0086410033371_,4.136336345,0.505003931,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,29013,DB01590,10033371,116,4622,72,2795,0.879012376,0.974254256,0.716980928,1.331356879,0.949136931,DB0159010033371_,0.052202201,-0.026082966,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,29016,DB01069,10037844,208,6492,62,2333,0.232889265,1.205580184,0.899967246,1.634588454,0.389395651,DB0106910037844_,0.943159353,0.186960932,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,promethazine,DB01069
,29017,DB01137,10037844,232,7540,155,5438,0.496760635,1.079515757,0.874346892,1.335685577,0.658913193,DB0113710037844_,0.417163478,0.076512568,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,levofloxacin,DB01137
,29018,DB01225,10037844,103,4941,89,4551,0.715366375,1.065973084,0.792450487,1.436192388,0.831475609,DB0122510037844_,0.184553315,0.063888076,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,enoxaparin,DB01225
,29020,DB00863,10046735,178,10495,72,5768,0.027965467,1.35869695,1.025658362,1.815828155,0.080151816,DB0086310046735_,2.523832744,0.306526115,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,29021,DB00904,10046735,191,22878,92,14364,0.037178597,1.303454641,1.010276799,1.69185647,0.099917124,DB0090410046735_,2.303414198,0.265018156,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,29022,DB01069,10046735,70,6630,19,2376,0.333500567,1.32025544,0.784080604,2.327208849,0.502540339,DB0106910046735_,0.688079365,0.277825233,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,promethazine,DB01069
,29023,DB01137,10046735,84,7688,48,5545,0.214984447,1.262172143,0.873415447,1.842186383,0.367380697,DB0113710046735_,1.001356647,0.232834159,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,levofloxacin,DB01137
,29025,DB01234,10046735,180,31445,146,32742,0.026263329,1.283719741,1.025633497,1.608974292,0.076347225,DB0123410046735_,2.572463588,0.249761911,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,29027,DB00169,10018964,84,38607,64,18111,0.004552678,0.615707943,0.439269571,0.866597136,0.018948166,DB0016910018964_,3.966048107,-0.484982546,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,29036,DB00863,10018964,34,10639,24,5816,0.338417802,0.774477597,0.445469814,1.366492268,0.507487124,DB0086310018964_,0.678283941,-0.255566546,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,29037,DB00996,10018964,52,38901,48,22377,0.021754516,0.62319991,0.412638189,0.942876954,0.066056425,DB0099610018964_,2.717245977,-0.472887928,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,29046,DB00169,10022595,53,38638,66,18109,1.70064924100291e-07,0.376373328,0.2570021,0.548838467,2.93895892832094e-06,DB0016910022595_,12.73745515,-0.977173736,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,29063,DB00005,10005003,19,128063,35,42384,6.86312500455682e-10,0.179666705,0.097073995,0.322833673,1.96618246043353e-08,DB0000510005003_,17.74458692,-1.716651782,male,10005003,Bladder cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,etanercept,DB00005
,29081,DB00203,10002855,251,13627,98,8840,1.51058458353898e-05,1.661460248,1.308346081,2.123862962,0.000155923,DB0020310002855_,8.766150181,0.507696883,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,sildenafil,DB00203
,29083,DB06403,10002855,205,21266,38,6623,0.002385062,1.68003372,1.182411873,2.44483425,0.01123199,DB0640310002855_,4.488989292,0.518813865,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ambrisentan,DB06403
,29084,DB01088,10016173,95,1334,12,425,0.001402374,2.521048909,1.361001912,5.101423778,0.007268345,DB0108810016173_,4.924226719,0.924675049,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,iloprost,DB01088
,29085,DB06403,10016173,423,21048,111,6550,0.122985117,1.18588886,0.958156572,1.477841636,0.245708493,DB0640310016173_,1.403609432,0.170492586,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ambrisentan,DB06403
,29086,DB00203,10019196,83,13795,35,8903,0.037222278,1.530441509,1.018392994,2.343742482,0.100003841,DB0020310019196_,2.302546683,0.425556261,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,29088,DB06403,10019196,64,21407,19,6642,1,1.04515221,0.617671386,1.848753739,1,DB0640310019196_,0,0.044162531,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,ambrisentan,DB06403
,29089,DB01088,10042772,42,1387,15,422,0.633616434,0.852016411,0.457395193,1.67125474,0.77213896,DB0108810042772_,0.258590746,-0.160149491,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,iloprost,DB01088
,29090,DB00203,10061024,235,13643,116,8822,0.017808144,1.309971622,1.042579569,1.653537295,0.056399428,DB0020310061024_,2.875296257,0.270005475,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,sildenafil,DB00203
,29092,DB00175,10005557,98,8033,81,6025,0.543542005,0.907452119,0.667824825,1.235937085,0.698699217,DB0017510005557_,0.358534934,-0.097114475,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,pravastatin,DB00175
,29093,DB00177,10005557,49,4751,27,2823,0.812176106,1.078344813,0.659227206,1.798695332,0.89905753,DB0017710005557_,0.106408254,0.075427285,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,valsartan,DB00177
,29094,DB00999,10005557,186,21244,113,12126,0.629100266,0.93954345,0.738874184,1.199074567,0.768200529,DB0099910005557_,0.263704475,-0.062361213,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,29095,DB01067,10005557,166,4195,180,4643,0.869332649,1.020711836,0.818095316,1.272890451,0.941838249,DB0106710005557_,0.059921729,0.020500263,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,glipizide,DB01067
,29096,DB06292,10005557,45,1312,45,1188,0.668424698,0.905523035,0.580868581,1.411600821,0.798549091,DB0629210005557_,0.224958834,-0.099242563,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,dapagliflozin,DB06292
,29100,DB00681,10013709,47,366,103,539,0.037684746,0.672244738,0.453775984,0.984693681,0.100983133,DB0068110013709_,2.292801781,-0.397132811,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,amphotericin b,DB00681
,29104,DB01067,10020993,88,4273,164,4659,5.18327668516807e-05,0.585093515,0.444814277,0.765348458,0.000455356,DB0106710020993_,7.69443167,-0.53598359,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,glipizide,DB01067
,29109,DB01156,10013754,108,13514,28,6300,0.005319613,1.798088181,1.175946229,2.834225178,0.021493249,DB0115610013754_,3.84001638,0.586723979,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,29111,DB06228,10037377,450,15462,412,15664,0.147037823,1.106497838,0.964070438,1.270212065,0.279821111,DB0622810037377_,1.273604771,0.101199926,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,29112,DB00028,10008531,289,13169,127,5488,0.624688746,0.948324692,0.765180304,1.180619891,0.764447202,DB0002810008531_,0.268602318,-0.053058333,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,29113,DB01109,10008531,63,4349,46,4224,0.149009426,1.330153465,0.892908355,1.994654502,0.282621695,DB0110910008531_,1.263646044,0.285294323,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,29114,DB00028,10037660,516,12942,245,5370,0.096010259,0.873905918,0.746583037,1.025074499,0.204806821,DB0002810037660_,1.585688081,-0.134782554,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,29124,DB09153,10033425,95,7704,50,5649,0.062833514,1.393150782,0.977253358,2.007002142,0.148683734,DB0915310033425_,1.905933819,0.331567932,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium chloride,DB09153
,29125,DB09153,10048959,86,7713,33,5666,0.001423383,1.914324419,1.265717469,2.957563559,0.007359815,DB0915310048959_,4.91172049,0.649364777,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,29126,DB09153,10064774,30,7769,20,5679,0.776447907,1.096490181,0.601718727,2.039329048,0.878124615,DB0915310064774_,0.129966765,0.092114334,NA,10064774,Infusion site extravasation,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,29127,DB00476,10022086,195,17062,27,6150,3.21626060263352e-07,2.603371511,1.732875874,4.055608405,5.19762741716706e-06,DB0047610022086_,12.1673083,0.95680734,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,29128,DB00656,10022086,164,11849,50,6569,0.000132497,1.818354253,1.315400266,2.552227053,0.001013738,DB0065610022086_,6.894110915,0.597931835,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,29129,DB00973,10022086,54,3797,23,2998,0.014807938,1.85360114,1.115524585,3.17259871,0.048818093,DB0097310022086_,3.019654276,0.617130309,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,29130,DB00451,10022093,198,47073,14,15405,1.12281962275016e-11,4.628367361,2.692946635,8.624076849,4.25877543780489e-10,DB0045110022093_,21.57686927,1.532204184,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,29131,DB00476,10022093,92,17165,6,6171,4.06781447687352e-07,5.51235291,2.436196015,15.42064831,6.42177198346069e-06,DB0047610022093_,11.95581647,1.706991557,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,29132,DB00656,10022093,47,11966,7,6612,0.000293449,3.709880284,1.66514731,9.736391404,0.001982347,DB0065610022093_,6.223473934,1.310999608,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,29134,DB00476,10022095,104,17153,17,6160,0.001756308,2.19699001,1.306802679,3.918055751,0.008737496,DB0047610022095_,4.740131685,0.787088246,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,29135,DB00656,10022095,94,11919,42,6577,0.281012985,1.2350315,0.848540285,1.824208004,0.444956016,DB0065610022095_,0.809779841,0.211096476,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,29138,DB00065,10033371,231,9233,75,4882,0.000197166,1.628515937,1.24679606,2.147521609,0.001423569,DB0006510033371_,6.554587976,0.487669132,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,29139,DB00065,10037844,337,9127,152,4805,0.121388086,1.16723074,0.957739917,1.427668234,0.243443013,DB0006510037844_,1.412872396,0.154634054,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,infliximab,DB00065
,29140,DB00065,10039073,204,9260,62,4895,8.7929154416225e-05,1.739261469,1.299999177,2.355283468,0.000715105,DB0006510039073_,7.243081838,0.55346058,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,infliximab,DB00065
,29141,DB00065,10047895,59,9405,50,4907,0.014716221,0.615658377,0.414501561,0.917621115,0.048570551,DB0006510047895_,3.02473787,-0.485063052,NA,10047895,Weight decreased,10022891,Investigations,Inv,infliximab,DB00065
,29142,DB00005,10048948,104,127978,20,42399,0.022271962,1.722679115,1.060287539,2.93650647,0.067234838,DB0000510048948_,2.699563738,0.543880704,NA,10048948,Bedridden,10041244,Social circumstances,SocCi,etanercept,DB00005
,29144,DB00694,10040070,28,606,36,735,0.897912954,0.943368869,0.547663346,1.610388131,0.956338178,DB0069410040070_,0.044643686,-0.058297907,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,daunorubicin,DB00694
,29145,DB00987,10040070,56,2048,95,2833,0.241909392,0.815452266,0.572432152,1.152431587,0.400062184,DB0098710040070_,0.916135283,-0.204012392,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,cytarabine,DB00987
,29153,DB00005,10049438,86,127996,28,42391,1,1.017230929,0.657169516,1.619192963,1,DB0000510049438_,0,0.01708416,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,29155,DB06703,10013968,85,690,34,377,0.15553689,1.365596861,0.887837355,2.139629569,0.291497124,DB0670310013968_,1.23272514,0.311591594,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gadobutrol,DB06703
,29161,DB00005,10010774,341,127741,92,42327,0.08439734,1.228148651,0.972595711,1.563961432,0.185724316,DB0000510010774_,1.683491877,0.205507874,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,29166,DB00678,10020583,38,15561,17,10707,0.169155016,1.538004936,0.846816529,2.907567825,0.309756137,DB0067810020583_,1.171969947,0.43048608,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,29170,DB01234,10020583,63,31562,70,32818,0.728913084,0.935791518,0.654856903,1.334947055,0.84197141,DB0123410020583_,0.172009221,-0.066362564,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,29172,DB06724,10020583,72,7857,64,3855,0.000664359,0.551978381,0.387775164,0.78729103,0.003927289,DB0672410020583_,5.539806028,-0.594246397,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,calcium carbonate,DB06724
,29175,DB00080,10005470,29,611,74,839,0.005109442,0.538335843,0.33339698,0.849357714,0.020818737,DB0008010005470_,3.871901897,-0.619272669,NA,10005470,Blood creatine phosphokinase increased,10022891,Investigations,Inv,daptomycin,DB00080
,29176,DB00264,10005470,24,29583,34,24858,0.063912971,0.593152009,0.336415188,1.030404204,0.150499659,DB0026410005470_,1.893794458,-0.522304575,NA,10005470,Blood creatine phosphokinase increased,10022891,Investigations,Inv,metoprolol,DB00264
,29186,DB00635,10061218,139,32914,59,23735,0.000511045,1.698893593,1.243655442,2.345941404,0.003143326,DB0063510061218_,5.762473709,0.529977211,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,29187,DB00188,10022061,61,7825,47,8781,0.053592635,1.45639226,0.978002579,2.180824197,0.131726427,DB0018810022061_,2.027028028,0.375962322,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,29189,DB00531,10025482,106,7146,86,6430,0.512653748,1.109032974,0.824842316,1.494671857,0.672851533,DB0053110025482_,0.396230578,0.103488441,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,29193,DB00264,10046571,681,28926,275,24617,4.16509749494655e-27,2.107387442,1.827487261,2.435845389,7.47300939622321e-25,DB0026410046571_,55.55332954,0.745449001,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,29194,DB00999,10046571,445,20985,94,12145,2.78781707531384e-22,2.739727753,2.185979162,3.463772942,3.62761246656556e-20,DB0099910046571_,44.76312715,1.007858555,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,29198,DB00207,10061922,25,9055,38,5417,0.000341873,0.393598779,0.227446647,0.670078982,0.002249664,DB0020710061922_,6.096974601,-0.932423217,NA,10061922,Pulmonary function test decreased,10022891,Investigations,Inv,azithromycin,DB00207
,29199,DB00355,10061922,44,1749,24,1239,0.322144681,1.29863307,0.76798712,2.245280309,0.490489932,DB0035510061922_,0.712350526,0.261312226,NA,10061922,Pulmonary function test decreased,10022891,Investigations,Inv,aztreonam,DB00355
,29200,DB00588,10061922,34,16490,27,8441,0.10333468,0.644589858,0.377212407,1.111591767,0.216039138,DB0058810061922_,1.532295693,-0.439141043,NA,10061922,Pulmonary function test decreased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,29201,DB00684,10061922,49,2743,50,2298,0.359676285,0.821047992,0.539954211,1.247891515,0.52937405,DB0068410061922_,0.636060009,-0.197173716,NA,10061922,Pulmonary function test decreased,10022891,Investigations,Inv,tobramycin,DB00684
,29213,DB01156,10002034,100,13522,45,6283,0.928701795,1.032522791,0.71838562,1.50451075,0.970364828,DB0115610002034_,0.030083167,0.032005119,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,bupropion,DB01156
,29215,DB14500,10002034,166,7643,68,4005,0.095073875,1.279207128,0.95641305,1.726824521,0.203337412,DB1450010002034_,1.592888551,0.246240455,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,potassium,DB14500
,29218,DB01156,10012218,28,13594,35,6293,0.000106944,0.370359573,0.216846079,0.627266006,0.00084529,DB0115610012218_,7.075830377,-0.993280927,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,29219,DB01234,10012218,49,31576,46,32842,0.681485267,1.107923733,0.72539141,1.694761404,0.807434868,DB0123410012218_,0.213892886,0.102487752,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,29222,DB01234,10012378,215,31410,177,32711,0.02249536,1.264993471,1.031326214,1.553277467,0.067708248,DB0123410012378_,2.692547276,0.235066961,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,29224,DB14500,10012378,95,7714,38,4035,0.169418735,1.307685492,0.886959679,1.962415711,0.310120231,DB1450010012378_,1.170795215,0.268258775,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,potassium,DB14500
,29226,DB01156,10020772,134,13488,55,6273,0.479939497,1.133091281,0.820698665,1.582886778,0.644801026,DB0115610020772_,0.438813496,0.124949545,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,bupropion,DB01156
,29228,DB14500,10020772,108,7701,46,4027,0.267117186,1.227665217,0.859786006,1.777482073,0.42939152,DB1450010020772_,0.845386143,0.205114168,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,potassium,DB14500
,29231,DB01234,10021015,144,31481,95,32793,0.000566156,1.578939323,1.20958889,2.069135667,0.0034218,DB0123410021015_,5.677588498,0.456753307,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,29233,DB14500,10021015,68,7741,26,4047,0.191296805,1.367290654,0.857023347,2.242728287,0.338191857,DB1450010021015_,1.08414192,0.312831157,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,potassium,DB14500
,29246,DB00999,10038695,79,21351,74,12165,0.002363707,0.608299936,0.436983302,0.847533765,0.0111464,DB0099910038695_,4.496638701,-0.497087203,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,29247,DB01156,10038695,63,13559,37,6291,0.281218508,0.790042951,0.517673722,1.221181753,0.4451836,DB0115610038695_,0.809268498,-0.235667966,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,29249,DB14500,10038695,50,7759,47,4026,0.004931058,0.552006075,0.362502932,0.841853902,0.020248546,DB1450010038695_,3.899672281,-0.594196227,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,29251,DB01156,10042128,47,13575,11,6317,0.046679285,1.988214406,1.015509634,4.25390913,0.118842375,DB0115610042128_,2.129957241,0.687236953,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,29253,DB14500,10042128,40,7769,19,4054,0.784935352,1.098550805,0.620615854,2.01111557,0.88325809,DB1450010042128_,0.124137833,0.093991861,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,29255,DB01234,10046571,580,31045,269,32619,3.81784004435616e-30,2.26543324,1.955476585,2.629899189,8.61389919020616e-28,DB0123410046571_,62.31900552,0.817766016,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,29257,DB14500,10046571,225,7584,54,4019,3.18506997214822e-08,2.207918265,1.629687963,3.037161047,6.40792684408082e-07,DB1450010046571_,14.26055986,0.79205011,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,potassium,DB14500
,29259,DB00999,10051398,50,21380,75,12164,1.02954315368665e-07,0.379305403,0.259564123,0.550137914,1.85989977970128e-06,DB0099910051398_,13.19498795,-0.969413586,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,hydrochlorothiazide,DB00999
,29261,DB14500,10051398,24,7785,39,4034,1.18863512547287e-05,0.318910553,0.183176645,0.544666047,0.000126286,DB1450010051398_,8.976957609,-1.142844614,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,potassium,DB14500
,29269,DB00999,10061428,386,21044,215,12024,0.797438313,1.025816417,0.864618073,1.21958091,0.890446532,DB0099910061428_,0.116032221,0.025488799,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,29270,DB01156,10061428,151,13471,56,6272,0.154237802,1.255391177,0.916643556,1.740688094,0.28985062,DB0115610061428_,1.238389593,0.227447219,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,bupropion,DB01156
,29272,DB14500,10061428,165,7644,80,3993,0.63416043,1.07738883,0.817603728,1.429403262,0.772495454,DB1450010061428_,0.258129155,0.074540364,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,potassium,DB14500
,29273,DB08908,10007882,42,10631,16,3263,0.440861407,0.805709489,0.44286621,1.537306453,0.609127528,DB0890810007882_,0.495727628,-0.216032036,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,dimethyl fumarate,DB08908
,29275,DB00451,10012601,160,47111,56,15363,0.635491762,0.931714609,0.682840315,1.287631383,0.773471984,DB0045110012601_,0.256865829,-0.070728724,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,29276,DB00588,10012601,58,16466,27,8441,0.731556857,1.101201727,0.685702257,1.810128075,0.843896963,DB0058810012601_,0.169724874,0.096402062,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,fluticasone propionate,DB00588
,29277,DB01067,10012601,44,4317,36,4787,0.179401748,1.355235238,0.850809304,2.171485902,0.323139514,DB0106710012601_,1.129671116,0.303975046,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,glipizide,DB01067
,29278,DB01067,10020772,57,4304,55,4768,0.505560232,1.148071978,0.776681838,1.69827918,0.666419265,DB0106710020772_,0.405836279,0.138083994,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,glipizide,DB01067
,29281,DB00451,10044055,83,47188,16,15403,0.060737628,1.69321626,0.983351625,3.099992739,0.1447537,DB0045110044055_,1.932721601,0.526629833,NA,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,29292,DB00005,10018092,46,128036,7,42412,0.055497794,2.176638461,0.976036279,5.715311098,0.13516419,DB0000510018092_,2.001265014,0.777781696,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,29293,DB00480,10015916,159,67269,148,67514,0.529878125,1.078205495,0.856278976,1.358363501,0.687082359,DB0048010015916_,0.375301111,0.07529808,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,lenalidomide,DB00480
,29294,DB01098,10015090,41,8108,48,7161,0.201652098,0.754419509,0.484234695,1.170513957,0.351056422,DB0109810015090_,1.046808322,-0.281806688,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,29297,DB00928,10033661,36,799,53,1233,0.825513962,1.048149816,0.660213869,1.647752449,0.907778709,DB0092810033661_,0.096754642,0.04702653,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,azacitidine,DB00928
,29299,DB00319,10002198,24,1368,42,1811,0.315635718,0.756538764,0.435924519,1.285581277,0.483293374,DB0031910002198_,0.727131411,-0.279001505,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,piperacillin,DB00319
,29300,DB00327,10002198,54,6084,6,4256,1.97465304050737e-07,6.294529244,2.708136088,17.92134773,3.35620789975662e-06,DB0032710002198_,12.60469882,1.839680882,female,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,hydromorphone,DB00327
,29301,DB00404,10002198,62,19830,15,9847,0.010532175,2.052449087,1.153158356,3.887227425,0.037099733,DB0040410002198_,3.294145509,0.719033756,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,alprazolam,DB00404
,29303,DB00620,10002198,41,4787,35,3097,0.239387165,0.757907689,0.469760047,1.228751083,0.397203019,DB0062010002198_,0.923307745,-0.277193683,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,triamcinolone,DB00620
,29312,DB00319,10037844,60,1332,74,1779,0.656879183,1.082879915,0.751416454,1.555225393,0.790227205,DB0031910037844_,0.235434773,0.07962408,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,piperacillin,DB00319
,29313,DB00327,10037844,129,6009,77,4185,0.316571349,1.166744701,0.870527683,1.57260559,0.484304508,DB0032710037844_,0.72504142,0.154217564,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,hydromorphone,DB00327
,29314,DB00448,10037844,129,5016,64,3060,0.201542835,1.229567425,0.90104745,1.692199462,0.350935936,DB0044810037844_,1.04715159,0.20666242,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,lansoprazole,DB00448
,29315,DB00620,10037844,220,4608,133,2999,0.540022477,1.076555635,0.859669204,1.35221318,0.695620828,DB0062010037844_,0.362950555,0.073766718,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,triamcinolone,DB00620
,29316,DB01255,10064355,70,2063,65,1513,0.184241781,0.789870587,0.55157741,1.132377889,0.329240275,DB0125510064355_,1.110967475,-0.235886161,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,lisdexamfetamine,DB01255
,29318,DB00437,10037153,40,6881,66,11480,1,1.011130861,0.664287771,1.521902403,1,DB0043710037153_,0,0.011069369,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,29319,DB00476,10037153,194,17063,59,6118,0.282690232,1.178959697,0.875343644,1.608372044,0.446814534,DB0047610037153_,0.805611682,0.164632437,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,duloxetine,DB00476
,29321,DB00814,10037153,193,8094,94,3321,0.188512679,0.842463789,0.652731384,1.093542244,0.334654089,DB0081410037153_,1.094657851,-0.171424598,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,meloxicam,DB00814
,29322,DB00158,10058080,48,16767,35,8069,0.077477089,0.659989604,0.417737514,1.052201842,0.174073449,DB0015810058080_,1.74827795,-0.415531196,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,folic acid,DB00158
,29323,DB00437,10058080,19,6902,39,11507,0.499323647,0.812259039,0.442946763,1.441165762,0.661145106,DB0043710058080_,0.413781938,-0.207935976,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,allopurinol,DB00437
,29324,DB00476,10058080,37,17220,27,6150,0.006404621,0.489417479,0.289781222,0.836583177,0.024940049,DB0047610058080_,3.691280371,-0.714539413,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,duloxetine,DB00476
,29327,DB05676,10058080,38,47091,29,25300,0.159683992,0.703966229,0.42272455,1.183864452,0.297027368,DB0567610058080_,1.213930998,-0.351024894,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,apremilast,DB05676
,29331,DB00158,10009033,74,16741,40,8064,0.549165327,0.89113874,0.598063702,1.345222166,0.703578901,DB0015810009033_,0.351575254,-0.115255152,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,29332,DB00316,10009033,327,65147,179,36774,0.780728532,1.031196972,0.856404105,1.244936053,0.880654413,DB0031610009033_,0.127089996,0.030720236,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,29333,DB00437,10009033,51,6870,77,11469,0.583447991,1.105719507,0.759547315,1.59782777,0.731448741,DB0043710009033_,0.312728135,0.100496261,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,29334,DB00451,10009033,241,47030,93,15326,0.180732454,0.844449741,0.661617228,1.085421572,0.324790795,DB0045110009033_,1.124574013,-0.169070057,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,29335,DB00563,10009033,127,46519,41,15307,1,1.019252568,0.711290269,1.487886317,1,DB0056310009033_,0,0.019069582,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,29336,DB00635,10009033,302,32751,173,23621,0.017145666,1.259019928,1.04016324,1.527773647,0.054751315,DB0063510009033_,2.904953883,0.230333583,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,29338,DB00983,10009033,69,3432,51,1689,0.031078302,0.665864655,0.454679692,0.980700645,0.08708528,DB0098310009033_,2.44086741,-0.406668851,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,formoterol,DB00983
,29339,DB08931,10009033,79,6498,32,2414,0.668394622,0.917139585,0.59932614,1.433572228,0.798543368,DB0893110009033_,0.224966001,-0.086495599,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,29340,DB00158,10037400,49,16766,16,8088,0.187076801,1.477343363,0.825272605,2.784953198,0.332858168,DB0015810037400_,1.100038803,0.39024545,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,29341,DB00316,10037400,173,65301,71,36882,0.023215851,1.376198403,1.037900377,1.841181061,0.069391477,DB0031610037400_,2.667991231,0.319324917,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,29342,DB00437,10037400,43,6878,46,11500,0.037140897,1.562851673,1.005714327,2.424585635,0.099878971,DB0043710037400_,2.303796113,0.446512148,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,29343,DB00451,10037400,179,47092,58,15361,1,1.006694361,0.744355701,1.378940741,1,DB0045110037400_,0,0.006672053,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,29345,DB00635,10037400,127,32926,61,23733,0.009401755,1.50066614,1.096851326,2.072353371,0.033882927,DB0063510037400_,3.384844018,0.405909103,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,29346,DB00641,10037400,60,14064,33,12442,0.028760667,1.608457638,1.034144707,2.541553796,0.081952857,DB0064110037400_,2.501611117,0.475275731,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,29349,DB00999,10037400,49,21381,14,12225,0.018424572,2.001153556,1.086644647,3.927044847,0.057915555,DB0099910037400_,2.848769281,0.693723792,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,29350,DB01409,10037400,50,5981,43,3923,0.202247553,0.762719268,0.496110681,1.176944416,0.351657843,DB0140910037400_,1.045096612,-0.270865248,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,29351,DB08931,10037400,230,6347,113,2333,0.015597211,0.748187542,0.59164314,0.950478616,0.05083224,DB0893110037400_,2.97922448,-0.290101608,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,29352,DB00158,10051055,78,16737,74,8030,3.80935762741893e-05,0.505707023,0.362729804,0.705581761,0.000350166,DB0015810051055_,7.957103018,-0.681797784,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,folic acid,DB00158
,29353,DB00374,10051055,43,17673,13,5711,1,1.06886667,0.563698282,2.168241838,1,DB0037410051055_,0,0.066598901,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,treprostinil,DB00374
,29354,DB00563,10051055,64,46582,53,15295,1.46501767890221e-06,0.396499361,0.271075647,0.582078628,2.01559747133968e-05,DB0056310051055_,10.8120098,-0.925080849,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,methotrexate,DB00563
,29355,DB00635,10051055,186,32867,176,23618,0.010218089,0.759434683,0.614187642,0.939274716,0.036180031,DB0063510051055_,3.319247948,-0.275180961,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,prednisone,DB00635
,29362,DB00983,10016173,66,3435,19,1721,0.036071391,1.740215628,1.027765092,3.081069324,0.097660454,DB0098310016173_,2.326258569,0.55400903,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,formoterol,DB00983
,29363,DB00983,10020751,39,3462,15,1725,0.468530587,1.295476031,0.695901699,2.53713209,0.634990666,DB0098310020751_,0.454144979,0.258878219,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,formoterol,DB00983
,29367,DB06228,10033661,34,15878,32,16044,0.806188247,1.07357176,0.642476039,1.798071482,0.895234916,DB0622810033661_,0.110669119,0.070991183,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,rivaroxaban,DB06228
,29371,DB00112,10005750,52,5881,40,4051,0.596184346,0.895488433,0.580384323,1.390825589,0.741603667,DB0011210005750_,0.298940319,-0.110385974,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,bevacizumab,DB00112
,29373,DB00112,10008469,33,5900,18,4073,0.476666283,1.265591928,0.691109265,2.390772907,0.64207719,DB0011210008469_,0.443046748,0.23553994,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,29374,DB01104,10033557,113,15350,20,7266,9.54706664846328e-06,2.674359989,1.65108106,4.547705285,0.000104451,DB0110410033557_,9.166788035,0.983710095,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,sertraline,DB01104
,29375,DB08932,10010264,1165,18278,377,6220,0.432568824,1.051575393,0.932052481,1.188463809,0.600986919,DB0893210010264_,0.50918211,0.050289414,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,29380,DB08932,10002034,806,18637,200,6397,3.9561840434154e-05,1.383212302,1.18016179,1.627346823,0.000361057,DB0893210002034_,7.92647377,0.324408549,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,macitentan,DB08932
,29383,DB01224,10020772,62,8046,34,5883,0.21316587,1.333283721,0.862614294,2.092425528,0.365210853,DB0122410020772_,1.007280413,0.287644863,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,quetiapine,DB01224
,29384,DB01224,10029282,32,8076,100,5817,4.72973189000579e-15,0.23051355,0.149506273,0.346857896,2.90809363108309e-13,DB0122410029282_,28.86610845,-1.467445634,male,10029282,Neuroleptic malignant syndrome,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,29385,DB01224,10037660,77,8031,87,5830,0.005276505,0.642530023,0.46568007,0.885064455,0.021350511,DB0122410037660_,3.846679583,-0.442341735,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,29386,DB01224,10043071,92,8016,54,5863,0.207500057,1.246089825,0.879412805,1.780746088,0.358247496,DB0122410043071_,1.026531203,0.220010509,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,quetiapine,DB01224
,29388,DB00047,10019211,325,8960,147,8371,9.80695881147409e-14,2.065458793,1.690610122,2.532928775,5.02977389969945e-12,DB0004710019211_,26.01564608,0.725352377,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,29389,DB01043,10019211,46,1355,22,1388,0.00308156,2.141260422,1.254341023,3.759629669,0.013830581,DB0104310019211_,4.280873154,0.761394638,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,memantine,DB01043
,29390,DB14500,10019211,439,7370,106,3967,7.16428803503878e-15,2.229087462,1.792378407,2.792682055,4.30922908469095e-13,DB1450010019211_,28.47284719,0.801592292,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,potassium,DB14500
,29391,DB01268,10013709,36,2107,67,3063,0.265366101,0.78114238,0.503968531,1.193294574,0.427372585,DB0126810013709_,0.850099081,-0.246997841,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,29392,DB00921,10028813,548,5297,361,4542,0.000193784,1.301604509,1.130751763,1.499603716,0.001403203,DB0092110028813_,6.568998135,0.263597741,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,buprenorphine,DB00921
,29393,DB00921,10047700,341,5504,225,4678,0.00419089,1.288079977,1.080287049,1.538120141,0.017741592,DB0092110047700_,4.031843548,0.253152719,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,buprenorphine,DB00921
,29394,DB00316,10003983,124,65350,78,36875,0.463727924,0.897047242,0.670164588,1.206937364,0.630937858,DB0031610003983_,0.460547903,-0.108646751,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,29396,DB00451,10003983,88,47183,31,15388,0.749192969,0.925794068,0.608232555,1.443503466,0.85776362,DB0045110003983_,0.153426719,-0.077103458,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,29398,DB00722,10003983,45,25358,36,25996,0.316899808,1.281439824,0.808074728,2.045388039,0.484694158,DB0072210003983_,0.724237189,0.247984308,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,29399,DB00924,10003983,39,10123,23,4228,0.208794289,0.708228879,0.412022846,1.243795173,0.359869729,DB0092410003983_,1.022013176,-0.344987962,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,29411,DB00654,10033371,69,3747,39,2559,0.374670743,1.208239171,0.801563346,1.844315725,0.544536523,DB0065410033371_,0.607820262,0.189164069,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,29415,DB00398,10053762,135,592,234,1304,0.044548719,1.27061493,0.998187101,1.613293968,0.114676632,DB0039810053762_,2.165639011,0.23950098,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sorafenib,DB00398
,29419,DB00193,10021519,39,19281,19,8683,0.777365255,0.924386372,0.521114507,1.694567662,0.878632827,DB0019310021519_,0.129388185,-0.078625143,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,29421,DB00264,10021519,59,29548,46,24846,0.768828973,1.078529649,0.720798319,1.622550977,0.873359676,DB0026410021519_,0.135407808,0.075598678,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,29428,DB00722,10021519,54,25349,38,25994,0.076708389,1.457192526,0.944265379,2.269198694,0.172722834,DB0072210021519_,1.756067083,0.376511657,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,29431,DB00996,10021519,66,38887,36,22389,0.837489957,1.055536093,0.692711729,1.631885758,0.916252462,DB0099610021519_,0.087463339,0.054048783,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,29435,DB00193,10051792,40,19280,29,8673,0.051449148,0.620486021,0.374918629,1.038516379,0.127738531,DB0019310051792_,2.05776983,-0.477252203,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,29437,DB00264,10051792,53,29554,63,24829,0.062668828,0.706781217,0.480819063,1.035364007,0.148420972,DB0026410051792_,1.907702638,-0.347034114,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,29441,DB00497,10051792,40,19227,31,16344,0.722259118,1.096806015,0.668792905,1.814378113,0.836398842,DB0049710051792_,0.178649696,0.092402334,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,29443,DB00722,10051792,47,25356,52,25980,0.763021191,0.92611879,0.610444386,1.401676626,0.86873333,DB0072210051792_,0.140719071,-0.07675277,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,29445,DB00993,10051792,31,3218,22,1597,0.240273301,0.699323445,0.390639259,1.272137731,0.398145545,DB0099310051792_,0.920937649,-0.357641919,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,azathioprine,DB00993
,29446,DB01050,10051792,51,18057,31,9340,0.48530194,0.850975357,0.533797427,1.376839976,0.649333749,DB0105010051792_,0.431808444,-0.161372109,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,29447,DB00448,10019211,269,4876,85,3039,2.34954293853291e-08,1.972270502,1.533030481,2.558602563,4.85135397795268e-07,DB0044810019211_,14.53883781,0.679185418,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lansoprazole,DB00448
,29449,DB01233,10019211,152,3269,39,1687,6.14807184710473e-05,2.011068904,1.398845938,2.952185191,0.000526477,DB0123310019211_,7.549303201,0.698666374,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,metoclopramide,DB01233
,29450,DB00193,10028735,95,19225,19,8683,0.000732249,2.258202325,1.368630789,3.917635199,0.004246009,DB0019310028735_,5.461775886,0.814569065,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,29451,DB00448,10028735,38,5107,16,3108,0.260141854,1.445307616,0.785331632,2.78135443,0.421450808,DB0044810028735_,0.864052215,0.368322182,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lansoprazole,DB00448
,29452,DB00451,10028735,345,46926,40,15379,2.00435818556868e-12,2.826751126,2.032504257,4.028426848,8.5805464019011e-11,DB0045110028735_,23.17893843,1.03912804,female,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,29453,DB00695,10028735,462,27587,115,20413,4.06546390246706e-30,2.972544636,2.416417911,3.681806279,9.09452924905078e-28,DB0069510028735_,62.26470955,1.089418366,female,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,29455,DB00996,10028735,190,38763,64,22361,0.000142544,1.712551536,1.283067107,2.311518092,0.001079763,DB0099610028735_,6.831013969,0.537984385,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,29457,DB00005,10042945,269,127813,17,42402,3.59554826314275e-17,5.249501551,3.217120735,9.145802356,2.82961036217686e-15,DB0000510042945_,33.49863737,1.658133129,female,10042945,Systemic lupus erythematosus,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,29458,DB00060,10007882,51,9457,18,2447,0.29450111,0.733146519,0.420225679,1.335988638,0.460387872,DB0006010007882_,0.775685946,-0.310409707,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,interferon beta-1a,DB00060
,29460,DB00060,10027175,283,9225,66,2399,0.460321493,1.11507044,0.846785113,1.486438786,0.62774661,DB0006010027175_,0.465618681,0.108917578,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,29475,DB00421,10020919,205,8698,63,5189,1.99041098826656e-06,1.941147125,1.453706391,2.622856269,2.63699359004972e-05,DB0042110020919_,10.54328599,0.6632791,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,spironolactone,DB00421
,29476,DB00656,10020919,32,11981,19,6600,0.771890038,0.927789683,0.509675237,1.733961193,0.875153866,DB0065610020919_,0.133355561,-0.074950207,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,trazodone,DB00656
,29477,DB00820,10020919,398,11517,135,5681,0.000173058,1.454206579,1.190142633,1.785776049,0.001277045,DB0082010020919_,6.663206452,0.374460445,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,tadalafil,DB00820
,29478,DB08932,10020919,613,18830,213,6384,0.775981065,0.975715956,0.831276768,1.148733456,0.877842147,DB0893210020919_,0.130288488,-0.024583764,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,macitentan,DB08932
,29479,DB14500,10020919,71,7738,27,4046,0.166343475,1.374930347,0.869866118,2.232043935,0.305907665,DB1450010020919_,1.184471972,0.318403073,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,potassium,DB14500
,29480,DB01164,10000081,211,6313,206,7730,0.024557281,1.254151057,1.027089501,1.531597564,0.072522683,DB0116410000081_,2.623855891,0.226458895,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,calcium chloride,DB01164
,29485,DB01076,10060800,121,25626,69,25514,0.00019583,1.745929597,1.28779446,2.383322256,0.001415868,DB0107610060800_,6.56001258,0.557287134,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,atorvastatin,DB01076
,29489,DB00316,10005396,36,65438,17,36936,0.668053026,1.19525804,0.654131699,2.269747041,0.798342817,DB0031610005396_,0.225217179,0.178362096,NA,10005396,Blood calcium increased,10022891,Investigations,Inv,acetaminophen,DB00316
,29493,DB00451,10005396,48,47223,7,15412,0.041420575,2.23777468,1.006524266,5.862790844,0.108582933,DB0045110005396_,2.220241039,0.805481926,NA,10005396,Blood calcium increased,10022891,Investigations,Inv,levothyroxine,DB00451
,29504,DB01373,10005396,73,22647,10,7371,0.006898346,2.376022604,1.220389508,5.164818201,0.026495656,DB0137310005396_,3.630774501,0.865427915,NA,10005396,Blood calcium increased,10022891,Investigations,Inv,calcium,DB01373
,29508,DB00186,10005483,80,16821,64,9944,0.083425661,0.738985026,0.524743706,1.044167076,0.184153962,DB0018610005483_,1.691983122,-0.302477621,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,lorazepam,DB00186
,29510,DB00281,10005483,34,11424,35,5636,0.002900079,0.479262572,0.289684672,0.792183318,0.013140592,DB0028110005483_,4.332049222,-0.735506665,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,lidocaine,DB00281
,29511,DB00341,10005483,40,11365,24,5044,0.277183001,0.739695417,0.4346518,1.284242096,0.440732877,DB0034110005483_,0.819316309,-0.301516776,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,cetirizine,DB00341
,29513,DB00437,10005483,67,6854,109,11437,0.875879402,1.025703992,0.743920347,1.405379576,0.946784697,DB0043710005483_,0.054683564,0.025379198,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,allopurinol,DB00437
,29519,DB00863,10005483,44,10629,29,5811,0.462267297,0.829513962,0.506889201,1.376373499,0.62947189,DB0086310005483_,0.462874081,-0.186915338,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,ranitidine,DB00863
,29520,DB01050,10005483,46,18062,57,9314,1.42566093433967e-05,0.41616423,0.27571602,0.625253757,0.000148439,DB0105010005483_,8.815334534,-0.876675313,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,ibuprofen,DB01050
,29521,DB01069,10005483,34,6666,25,2370,0.007226811,0.48355725,0.279475629,0.847388178,0.027454363,DB0106910005483_,3.595230185,-0.726585563,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,promethazine,DB01069
,29523,DB01373,10005483,78,22642,39,7342,0.030992652,0.64853992,0.435729377,0.979457328,0.086909037,DB0137310005483_,2.442893254,-0.43303172,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,calcium,DB01373
,29532,DB00437,10005725,26,6895,33,11513,0.345660342,1.315521278,0.754916474,2.270157671,0.515075942,DB0043710005725_,0.663440928,0.274232996,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,allopurinol,DB00437
,29538,DB00904,10005725,36,23033,27,14429,0.517745356,0.835275788,0.49290516,1.431160482,0.677263695,DB0090410005725_,0.389694576,-0.179993323,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,ondansetron,DB00904
,29549,DB00316,10005851,75,65399,62,36891,0.032211075,0.682399747,0.48078368,0.971510473,0.089547128,DB0031610005851_,2.412990224,-0.382139654,NA,10005851,Blood urea increased,10022891,Investigations,Inv,acetaminophen,DB00316
,29552,DB00451,10005851,65,47206,33,15386,0.04522571,0.641994887,0.415900664,1.00826088,0.116010325,DB0045110005851_,2.154076086,-0.44317494,NA,10005851,Blood urea increased,10022891,Investigations,Inv,levothyroxine,DB00451
,29566,DB00186,10012174,307,16594,157,9851,0.133419007,1.160854257,0.953025413,1.418449483,0.260553408,DB0018610012174_,1.344947416,0.149156163,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,lorazepam,DB00186
,29567,DB00227,10012174,43,2424,27,1776,0.625827091,1.166789474,0.701695314,1.971792094,0.765359191,DB0022710012174_,0.267410024,0.154255938,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,lovastatin,DB00227
,29568,DB00281,10012174,129,11329,77,5594,0.205339338,0.827260757,0.617832289,1.113893313,0.355569499,DB0028110012174_,1.034034551,-0.189635329,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,lidocaine,DB00281
,29569,DB00364,10012174,62,2688,34,1366,0.743624192,0.926708081,0.597093486,1.460008045,0.853432383,DB0036410012174_,0.158488963,-0.07611667,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,sucralfate,DB00364
,29571,DB00571,10012174,36,5087,24,2585,0.33741179,0.762290826,0.441333102,1.338669791,0.506589872,DB0057110012174_,0.680053533,-0.271427135,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,propranolol,DB00571
,29572,DB00584,10012174,26,2055,35,1839,0.122291929,0.664850174,0.382718329,1.141452528,0.244714199,DB0058410012174_,1.407664285,-0.408193566,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,enalapril,DB00584
,29573,DB00904,10012174,645,22424,403,14053,0.974329669,1.003022336,0.882647271,1.140856126,1,DB0090410012174_,0,0.003017778,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,29574,DB01069,10012174,143,6557,68,2327,0.057335041,0.746334039,0.553071358,1.015459359,0.138433065,DB0106910012174_,1.977368356,-0.292582006,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,promethazine,DB01069
,29575,DB01190,10012174,33,4901,22,2263,0.191391115,0.692639771,0.390878473,1.250055869,0.338324452,DB0119010012174_,1.083749925,-0.367245226,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,clindamycin,DB01190
,29576,DB01373,10012174,269,22451,112,7269,0.030770461,0.777637413,0.620506036,0.979880269,0.086424275,DB0137310012174_,2.44848668,-0.251494914,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,calcium,DB01373
,29577,DB05351,10012174,39,2684,12,1119,0.439488226,1.354825034,0.691851989,2.853554911,0.60790361,DB0535110012174_,0.497738946,0.30367232,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,dexlansoprazole,DB05351
,29578,DB14512,10012174,35,4809,23,2389,0.327498065,0.756024159,0.433120628,1.343364012,0.49592618,DB1451210012174_,0.701328195,-0.279681947,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,mometasone furoate,DB14512
,29601,DB00227,10028813,147,2320,51,1752,9.63855363985966e-07,2.176272651,1.562273133,3.073834702,1.38555855851086e-05,DB0022710028813_,11.18682212,0.77761362,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lovastatin,DB00227
,29602,DB00364,10028813,247,2503,78,1322,8.77150661214159e-05,1.672333588,1.279483393,2.205149963,0.000713474,DB0036410028813_,7.245364873,0.514220009,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sucralfate,DB00364
,29603,DB00540,10028813,118,2365,39,1052,0.131592533,1.345796668,0.922279882,2.000699423,0.258031311,DB0054010028813_,1.354674339,0.296986156,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,nortriptyline,DB00540
,29604,DB14512,10028813,228,4616,67,2345,6.59804474838908e-05,1.728650432,1.304669322,2.316063846,0.000557921,DB1451210028813_,7.491293971,0.547341007,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,mometasone furoate,DB14512
,29605,DB00281,10033371,439,11019,167,5504,0.003202103,1.313062647,1.092872746,1.583427263,0.01426685,DB0028110033371_,4.249816591,0.272362307,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,29606,DB00364,10033371,140,2610,36,1364,0.000115592,2.032046655,1.391007506,3.036608734,0.000903061,DB0036410033371_,7.009720945,0.70904349,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sucralfate,DB00364
,29607,DB00540,10033371,118,2365,26,1065,0.000815749,2.043394558,1.318090852,3.276737685,0.004654215,DB0054010033371_,5.369982017,0.714612424,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,nortriptyline,DB00540
,29608,DB00571,10033371,158,4965,48,2561,0.001263389,1.697770497,1.217259681,2.405501431,0.006665631,DB0057110033371_,5.010790692,0.529315918,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,29609,DB00584,10033371,66,2015,45,1829,0.149109064,1.331183702,0.892550597,2.001028178,0.282759667,DB0058410033371_,1.263157975,0.286068548,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,enalapril,DB00584
,29610,DB00727,10033371,175,3668,102,4071,2.33077512219988e-07,1.904016639,1.47671073,2.465603915,3.89970872609954e-06,DB0072710033371_,12.45460869,0.643965675,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,29611,DB00829,10033371,374,7678,138,4316,2.15412655470346e-05,1.523392965,1.245281648,1.872288554,0.000212815,DB0082910033371_,8.455088827,0.420940061,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,29612,DB00863,10033371,486,10187,145,5695,8.43792340294817e-12,1.873700599,1.548754669,2.277956436,3.26402967838841e-10,DB0086310033371_,21.8428884,0.627915406,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,29613,DB01069,10033371,389,6311,66,2329,7.10401170568817e-10,2.174934259,1.663844646,2.880600535,2.02966247482623e-08,DB0106910033371_,17.71281123,0.776998439,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,29614,DB01190,10033371,123,4811,44,2241,0.152346285,1.302147752,0.9121524,1.888713975,0.287230363,DB0119010033371_,1.247470726,0.264015018,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,clindamycin,DB01190
,29615,DB05351,10033371,103,2620,35,1096,0.341079128,1.230972739,0.825485584,1.874303588,0.510275426,DB0535110033371_,0.672804649,0.207804701,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,dexlansoprazole,DB05351
,29616,DB14512,10033371,137,4707,28,2384,3.3366621150746e-06,2.477873028,1.635269856,3.877343103,4.15364260926999e-05,DB1451210033371_,10.08893978,0.907400542,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,29621,DB00437,10038428,41,6880,67,11479,0.920832753,1.0210064,0.673985537,1.530150444,0.964924382,DB0043710038428_,0.035705541,0.020788808,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,allopurinol,DB00437
,29622,DB00451,10038428,168,47103,66,15353,0.196738503,0.829659321,0.620167069,1.121111317,0.345061993,DB0045110038428_,1.064031187,-0.186740119,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,29628,DB00863,10038428,33,10640,17,5823,0.883447755,1.062356967,0.574428652,2.03541728,0.951268864,DB0086310038428_,0.04995854,0.060489993,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,ranitidine,DB00863
,29629,DB00904,10038428,70,22999,51,14405,0.454269271,0.859678673,0.590382917,1.259323472,0.621737453,DB0090410038428_,0.475237376,-0.151196596,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,ondansetron,DB00904
,29630,DB01050,10038428,24,18084,34,9337,0.000142754,0.364469725,0.206678934,0.633378608,0.001081043,DB0105010038428_,6.829828579,-1.009311791,male,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,ibuprofen,DB01050
,29633,DB01373,10038428,64,22656,38,7343,0.00384916,0.545893835,0.359500548,0.839071085,0.016535945,DB0137310038428_,4.102218798,-0.605330763,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,calcium,DB01373
,29636,DB14513,10038428,36,7141,29,3535,0.063352838,0.614533436,0.36573103,1.040934739,0.149569259,DB1451310038428_,1.899995724,-0.48689194,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,magnesium,DB14513
,29643,DB00451,10061225,110,47161,25,15394,0.109496298,1.436186459,0.923266764,2.31580461,0.22532289,DB0045110061225_,1.490220841,0.361991308,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,29650,DB00904,10061225,52,23017,34,14422,0.911748609,0.958326728,0.609892989,1.523634847,0.96047581,DB0090410061225_,0.040326482,-0.042566507,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,29651,DB01050,10061225,41,18067,26,9345,0.439579171,0.815670883,0.486793335,1.389758321,0.607927575,DB0105010061225_,0.497699523,-0.203744335,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,29654,DB01373,10061225,54,22666,13,7368,0.394332409,1.350255258,0.726688364,2.698762974,0.564236656,DB0137310061225_,0.572281512,0.300293655,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,29680,DB08934,10003988,44,4445,50,6154,0.3466028,1.218309835,0.792089993,1.868106358,0.516056111,DB0893410003988_,0.661539777,0.197464517,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sofosbuvir,DB08934
,29686,DB00451,10029174,41,47230,11,15408,0.63210869,1.215951743,0.613601507,2.623797326,0.770799885,DB0045110029174_,0.260326492,0.195527097,NA,10029174,Nerve compression,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,29688,DB00996,10029174,47,38906,19,22406,0.203352747,1.424588903,0.819965736,2.571083712,0.353077335,DB0099610029174_,1.041068168,0.353883283,NA,10029174,Nerve compression,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,29696,DB00110,10061603,120,411,176,512,0.252174622,0.849483901,0.644617308,1.117115775,0.412314196,DB0011010061603_,0.885969608,-0.16312629,NA,10061603,Respiratory syncytial virus infection,10021881,Infections and infestations,Infec,palivizumab,DB00110
,29719,DB00811,10042458,24,2774,48,4108,0.276900225,0.740478352,0.43272138,1.236191077,0.440376489,DB0081110042458_,0.820125262,-0.300458881,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,ribavirin,DB00811
,29722,DB00175,10029354,58,8073,40,6066,0.758849085,1.089537563,0.714774992,1.675497497,0.865539085,DB0017510029354_,0.144402747,0.085753353,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,pravastatin,DB00175
,29725,DB00736,10029354,65,10526,42,5511,0.307498313,0.810298558,0.540562883,1.226195466,0.474650784,DB0073610029354_,0.745175936,-0.21035251,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,esomeprazole,DB00736
,29726,DB01136,10029354,55,9829,80,11035,0.142463708,0.771865694,0.536762746,1.102955332,0.27325251,DB0113610029354_,1.297358965,-0.258944716,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,carvedilol,DB01136
,29727,DB08910,10029354,265,16479,268,17220,0.72691512,1.033277043,0.867416036,1.230820277,0.840298033,DB0891010029354_,0.173998649,0.032735347,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,pomalidomide,DB08910
,29729,DB00316,10037868,41,65433,32,36921,0.180342511,0.722980438,0.44417347,1.186262545,0.324267394,DB0031610037868_,1.126186814,-0.324373114,NA,10037868,Rash maculo-papular,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,29733,DB01234,10037868,33,31592,42,32846,0.419474146,0.816905844,0.501538378,1.32050671,0.588423413,DB0123410037868_,0.5303085,-0.202231436,NA,10037868,Rash maculo-papular,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,29737,DB00316,10050528,40,65434,36,36917,0.0427208,0.626847708,0.38945599,1.012315981,0.111157813,DB0031610050528_,2.196804348,-0.467051658,NA,10050528,Ejection fraction decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,29740,DB01136,10050528,35,9849,37,11078,0.813894776,1.063949507,0.650174872,1.738040522,0.90016091,DB0113610050528_,0.105181743,0.061987934,NA,10050528,Ejection fraction decreased,10022891,Investigations,Inv,carvedilol,DB01136
,29741,DB01234,10050528,36,31589,19,32869,0.015221457,1.971478798,1.1010252,3.63939373,0.049884172,DB0123410050528_,2.998051516,0.67878392,NA,10050528,Ejection fraction decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,29743,DB00215,10013754,48,11055,19,5257,0.600454322,1.201311072,0.692286871,2.166480414,0.7448473,DB0021510013754_,0.294576048,0.18341352,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,29744,DB00215,10020772,130,10973,49,5227,0.172201847,1.26373263,0.901671582,1.796322216,0.313729027,DB0021510020772_,1.159225637,0.234069746,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,citalopram,DB00215
,29745,DB00820,10000060,253,11662,82,5734,0.000973651,1.516986872,1.175547433,1.974694762,0.005389846,DB0082010000060_,5.223238387,0.416726046,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,29746,DB00820,10013946,162,11753,64,5752,0.154374539,1.238763428,0.920337623,1.684540997,0.289983189,DB0082010013946_,1.237932325,0.214113646,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,29747,DB08932,10013946,376,19067,85,6512,0.000436964,1.510705065,1.188808856,1.938323144,0.002759638,DB0893210013946_,5.89265591,0.412576472,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,29748,DB08932,10036790,383,19060,116,6481,0.298691557,1.122683582,0.907962218,1.396850138,0.464713817,DB0893210036790_,0.76633351,0.115721875,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,29749,DB01164,10037660,37,6487,54,7882,0.400457865,0.832542097,0.531968205,1.290296226,0.570284978,DB0116410037660_,0.561619083,-0.183271491,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,29750,DB00983,10028334,48,3453,9,1731,0.004327156,2.673205805,1.293449118,6.211622516,0.018211401,DB0098310028334_,4.005707427,0.983278428,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,formoterol,DB00983
,29753,DB08932,10046735,94,19349,24,6573,0.243271583,1.33048984,0.841665816,2.180876864,0.401607433,DB0893210046735_,0.912280202,0.285547175,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,macitentan,DB08932
,29754,DB00761,10028735,189,15118,48,8577,1.29957037533183e-07,2.233820427,1.61766625,3.137688259,2.30649610503694e-06,DB0076110028735_,12.97978102,0.803713316,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,29755,DB00820,10028735,502,11413,116,5700,3.44092885843166e-15,2.161245551,1.758062985,2.675119374,2.1637515560736e-13,DB0082010028735_,29.16176266,0.770684699,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,29756,DB11089,10028735,53,10122,16,8391,0.000223203,2.745795716,1.544352934,5.149283495,0.001579666,DB1108910028735_,6.450541955,1.010070911,female,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,29757,DB08931,10006451,129,6448,18,2428,1.41304181691921e-05,2.698206966,1.636816475,4.707923878,0.000147271,DB0893110006451_,8.823234571,0.992587466,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,riociguat,DB08931
,29758,DB08932,10006451,433,19010,69,6528,1.89251822928734e-10,2.154972568,1.665253122,2.824443515,5.90470944362185e-09,DB0893210006451_,18.94751559,0.767777994,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,macitentan,DB08932
,29759,DB00820,10040742,70,11845,26,5790,0.275569372,1.316060733,0.82716806,2.15365067,0.438868371,DB0082010040742_,0.823555749,0.274642982,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,29760,DB08931,10040742,47,6530,14,2432,0.563485677,1.250274552,0.675242007,2.46359092,0.715396963,DB0893110040742_,0.334917698,0.223363169,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,29761,DB08932,10040742,132,19311,40,6557,0.597729821,1.120500261,0.780376531,1.64057472,0.742836704,DB0893210040742_,0.297279038,0.113775248,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,29763,DB00656,10021097,225,11788,181,6438,0.000154274,0.67889959,0.554400816,0.832366736,0.001154965,DB0065610021097_,6.763685533,-0.387282042,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,trazodone,DB00656
,29764,DB00661,10021097,146,3382,74,1521,0.413638998,0.887340142,0.661692722,1.198202042,0.583007188,DB0066110021097_,0.539555763,-0.119526896,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,verapamil,DB00661
,29765,DB00656,10021143,74,11939,28,6591,0.096915548,1.458977861,0.931783596,2.343947578,0.206127376,DB0065610021143_,1.57926097,0.377736095,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,29767,DB00661,10033295,50,3478,40,1555,0.00794805,0.558966336,0.359728332,0.873365477,0.029633261,DB0066110033295_,3.518857855,-0.58166603,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,verapamil,DB00661
,29768,DB00656,10040560,10,12003,58,6561,2.97047191278656e-17,0.094273977,0.042919285,0.186162765,2.36961621328057e-15,DB0065610040560_,33.67604839,-2.361550087,male,10040560,Shock,10047065,Vascular disorders,Vasc,trazodone,DB00656
,29775,DB00046,10010774,60,5399,52,4640,1,0.991636669,0.671072589,1.469605768,1,DB0004610010774_,0,-0.0083985,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,insulin lispro,DB00046
,29776,DB01307,10010774,42,2482,36,2033,0.908739989,0.955600705,0.595122809,1.54146627,0.95913476,DB0130710010774_,0.041723693,-0.045415126,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,insulin detemir,DB01307
,29777,DB00264,10041349,313,29294,220,24672,0.044349417,1.198244984,1.004359957,1.431515965,0.114303068,DB0026410041349_,2.168901863,0.180857973,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,29778,DB00338,10041349,339,33335,183,22089,0.027649226,1.227485355,1.021647386,1.478662587,0.079449018,DB0033810041349_,2.532639742,0.20496765,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,29779,DB08932,10041349,233,19210,70,6527,0.388387011,1.130944818,0.860948707,1.501520122,0.558404583,DB0893210041349_,0.58267152,0.123053406,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,29780,DB00005,10014062,53,128029,11,42408,0.19238264,1.595907533,0.82378838,3.388670562,0.339620384,DB0000510014062_,1.079926803,0.467442561,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,29784,DB00007,10021097,8,1939,49,4403,0.005666962,0.370781665,0.151381014,0.791406074,0.022615364,DB0000710021097_,3.789125764,-0.992141895,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,leuprolide,DB00007
,29786,DB08931,10012735,1075,5502,272,2174,2.49947125825544e-10,1.56155925,1.352917071,1.806702063,7.67507032981826e-09,DB0893110012735_,18.68528838,0.445684841,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,29787,DB08931,10016256,898,5679,250,2196,1.02796432160435e-05,1.388934771,1.195311412,1.6180908,0.000111212,DB0893110016256_,9.104068077,0.328537102,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,29788,DB08931,10019211,1317,5260,312,2134,2.74004254794419e-16,1.712440438,1.49688491,1.96312119,1.95181621606268e-14,DB0893110019211_,31.56743097,0.53791951,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,29789,DB08931,10021097,915,5662,316,2130,0.227380756,1.089287527,0.948113155,1.253706419,0.382619197,DB0893110021097_,0.960715049,0.085523837,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,riociguat,DB08931
,29790,DB08931,10028813,1186,5391,263,2183,5.41344548302531e-18,1.825940336,1.581263979,2.113956818,4.68067153030659e-16,DB0893110028813_,35.2979199,0.602095107,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,29791,DB08931,10033371,408,6169,117,2329,0.009871737,1.316446948,1.063114426,1.640216394,0.03519955,DB0893110033371_,3.346721975,0.274936402,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,29792,DB08931,10035664,552,6025,177,2269,0.074866617,1.174442384,0.982712582,1.40877841,0.169629257,DB0893110035664_,1.774140062,0.160793468,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,riociguat,DB08931
,29793,DB08931,10047700,686,5891,148,2298,3.8413454189316e-11,1.807998318,1.501309632,2.188606933,1.34179088819425e-09,DB0893110047700_,20.42926063,0.592220332,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,29795,DB00203,10027599,174,13704,33,8905,4.56366816862498e-13,3.426100613,2.348280178,5.138754493,2.13634938223166e-11,DB0020310027599_,24.56933755,1.231422767,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,29796,DB00374,10027599,228,17488,32,5692,1.35210954163593e-06,2.319135451,1.594933135,3.475669633,1.8769579773911e-05,DB0037410027599_,10.8832731,0.841194466,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,29797,DB00559,10027599,55,9604,12,3294,0.20479733,1.571895084,0.830417161,3.22948276,0.354816453,DB0055910027599_,1.036154658,0.452281951,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,bosentan,DB00559
,29798,DB00682,10027599,143,19316,33,16331,7.83860970354614e-14,3.66345633,2.493095972,5.527155635,4.08400111115382e-12,DB0068210027599_,26.22394394,1.298407054,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,29799,DB00451,10030095,353,46918,95,15324,0.098629962,1.213613819,0.964295516,1.539888224,0.208827464,DB0045110030095_,1.566246897,0.193602536,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,29800,DB00996,10030095,212,38741,97,22328,0.066194587,1.25965349,0.985450333,1.619610116,0.154508655,DB0099610030095_,1.867505162,0.230836676,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,29801,DB01076,10030095,160,25587,119,25464,0.016339018,1.338062382,1.048162454,1.712049305,0.052680795,DB0107610030095_,2.94350432,0.291222584,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,29802,DB01104,10030095,91,15372,21,7265,0.00218286,2.047931683,1.262263597,3.469841474,0.010453447,DB0110410030095_,4.560823488,0.716830349,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,29804,DB00497,10047899,244,19023,98,16277,5.76665071420836e-11,2.130292591,1.676747318,2.724029094,1.95708733406026e-09,DB0049710047899_,20.05180852,0.756259337,NA,10047899,Weight increased,10022891,Investigations,Inv,oxycodone,DB00497
,29805,DB00635,10047899,651,32402,229,23565,8.07787056158102e-23,2.067436835,1.773985014,2.416284997,1.08330014138345e-20,DB0063510047899_,45.97168979,0.726309596,NA,10047899,Weight increased,10022891,Investigations,Inv,prednisone,DB00635
,29806,DB00996,10047899,633,38320,239,22186,1.06627571822483e-08,1.533402969,1.318034857,1.788633712,2.38528146838634e-07,DB0099610047899_,15.24877852,0.427489428,NA,10047899,Weight increased,10022891,Investigations,Inv,gabapentin,DB00996
,29807,DB01076,10047899,371,25376,263,25320,2.6094059922938e-05,1.407517785,1.197385993,1.656417866,0.000250545,DB0107610047899_,8.291873891,0.341827717,NA,10047899,Weight increased,10022891,Investigations,Inv,atorvastatin,DB01076
,29808,DB01104,10047899,291,15172,109,7177,0.039902253,1.26284156,1.008074233,1.591535826,0.105505556,DB0110410047899_,2.248991668,0.233364388,NA,10047899,Weight increased,10022891,Investigations,Inv,sertraline,DB01104
,29809,DB01118,10047899,32,3031,42,4667,0.550383856,1.17311682,0.715058042,1.907949961,0.704616791,DB0111810047899_,0.350101182,0.159664155,NA,10047899,Weight increased,10022891,Investigations,Inv,amiodarone,DB01118
,29810,DB08932,10047899,723,18720,231,6366,0.426113176,1.064353625,0.913919879,1.243116842,0.594791024,DB0893210047899_,0.519545155,0.06236769,NA,10047899,Weight increased,10022891,Investigations,Inv,macitentan,DB08932
,29828,DB01238,10001488,51,5199,98,3404,1.8439645475253e-10,0.340774894,0.23732867,0.484241525,5.77694971772377e-09,DB0123810001488_,18.96939002,-1.076533155,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,29831,DB08932,10015090,400,19043,121,6476,0.285266915,1.124199808,0.913206747,1.392161897,0.449844969,DB0893210015090_,0.798852269,0.1170715,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,29833,DB01238,10029282,27,5223,47,3455,6.25450355296467e-05,0.38005057,0.227150177,0.624231543,0.000533678,DB0123810029282_,7.535717179,-0.967450957,NA,10029282,Neuroleptic malignant syndrome,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,29837,DB01217,10003239,156,2598,10,258,0.207779908,1.548999222,0.806483465,3.335859484,0.358624657,DB0121710003239_,1.025478962,0.437609059,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,anastrozole,DB01217
,29846,DB01098,10000891,24,8125,48,7161,0.000838419,0.440697508,0.257908496,0.734619414,0.004758767,DB0109810000891_,5.347766749,-0.819396562,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,rosuvastatin,DB01098
,29848,DB01098,10005425,69,8080,48,7161,0.22669101,1.27398041,0.867445402,1.884388641,0.381800737,DB0109810005425_,0.962856437,0.242146181,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,rosuvastatin,DB01098
,29851,DB01307,10018484,38,2486,14,2055,0.010919512,2.243290789,1.18424065,4.495242157,0.038197948,DB0130710018484_,3.264973483,0.80794389,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,insulin detemir,DB01307
,29856,DB01098,10024910,39,8110,32,7177,0.812024357,1.078564943,0.657666647,1.780479277,0.89903796,DB0109810024910_,0.10643002,0.075631401,NA,10024910,Low density lipoprotein increased,10022891,Investigations,Inv,rosuvastatin,DB01098
,29858,DB00331,10053762,596,24350,423,20329,0.011926806,1.17630835,1.03526517,1.337462147,0.040955791,DB0033110053762_,3.195262068,0.162381018,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,29859,DB01307,10053762,56,2468,51,2018,0.623413801,0.897851437,0.600385577,1.34529099,0.763455716,DB0130710053762_,0.269900157,-0.107750662,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin detemir,DB01307
,29860,DB01098,10061024,50,8099,49,7160,0.615119661,0.902108385,0.595207278,1.367888807,0.756544533,DB0109810061024_,0.278993881,-0.103020606,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,rosuvastatin,DB01098
,29864,DB00619,10015967,54,2845,23,2471,0.003823672,2.038878824,1.226170592,3.49160548,0.016447205,DB0061910015967_,4.107599706,0.712400061,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,imatinib,DB00619
,29865,DB00588,10037377,119,16405,77,8391,0.111929927,0.790512816,0.587780968,1.068426583,0.228982226,DB0058810037377_,1.474110895,-0.23507341,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,29866,DB00635,10037377,209,32844,202,23592,0.003030322,0.743210097,0.609132505,0.906942412,0.013629708,DB0063510037377_,4.295503468,-0.296776506,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,29867,DB00959,10037377,61,8017,27,4975,0.153498986,1.401962683,0.876271848,2.297666467,0.28887324,DB0095910037377_,1.241767302,0.337873171,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,29870,DB01222,10037377,63,9211,38,5367,0.917613483,0.965985627,0.634881995,1.487475999,0.963386915,DB0122210037377_,0.037300167,-0.034606324,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,29872,DB00254,10003549,102,5833,74,3314,0.114149116,0.783157929,0.573067879,1.074559902,0.232346228,DB0025410003549_,1.459526656,-0.244420906,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,29874,DB01112,10013968,54,1091,23,556,0.538093131,1.196359346,0.713205269,2.065221335,0.694105018,DB0111210013968_,0.365132008,0.179283067,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cefuroxime,DB01112
,29875,DB00254,10016256,319,5616,142,3246,0.011282351,1.298393145,1.056926447,1.60134852,0.039179944,DB0025410016256_,3.239590305,0.261127458,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,29876,DB01112,10016256,62,1083,27,552,0.565175891,1.170333751,0.724104038,1.936369291,0.716833058,DB0111210016256_,0.332912299,0.157288965,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cefuroxime,DB01112
,29877,DB00343,10018964,33,8703,25,5070,0.340881422,0.769007563,0.442999832,1.350559186,0.510109204,DB0034310018964_,0.673130451,-0.262654475,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,29878,DB00381,10018964,79,29281,48,22839,0.180094249,1.283732767,0.885289174,1.878710675,0.323920715,DB0038110018964_,1.127256501,0.249772058,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,29879,DB00641,10018964,19,14105,39,12436,0.002222486,0.429544344,0.234297145,0.761908119,0.010601225,DB0064110018964_,4.546785748,-0.845030296,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,29880,DB00695,10018964,103,27946,98,20430,0.063133759,0.768363191,0.576659563,1.024372835,0.149186034,DB0069510018964_,1.902561199,-0.263492752,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,29884,DB00343,10035664,543,8193,258,4837,0.005209243,1.242506761,1.064695723,1.452921767,0.021141814,DB0034310035664_,3.856502473,0.21713092,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,diltiazem,DB00343
,29885,DB01112,10035664,81,1064,56,523,0.072822923,0.711101225,0.491142507,1.035406102,0.166235516,DB0111210035664_,1.794349727,-0.34094049,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cefuroxime,DB01112
,29886,DB01275,10035664,167,3812,131,3218,0.553153403,1.076179418,0.84669198,1.370110265,0.706785465,DB0127510035664_,0.347028103,0.073417194,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,hydralazine,DB01275
,29887,DB00316,10036790,211,65263,106,36847,0.348850765,1.123874209,0.885517996,1.433490046,0.518360742,DB0031610036790_,0.657083866,0.116781831,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,29888,DB00343,10036790,74,8662,28,5067,0.050440281,1.545942892,0.986955642,2.484758174,0.12581351,DB0034310036790_,2.072954544,0.43563401,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,29889,DB00381,10036790,136,29224,45,22842,1.60125637880138e-07,2.362146338,1.67404782,3.388742643,2.78366560296258e-06,DB0038110036790_,12.79174194,0.859570671,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,29890,DB00641,10036790,67,14057,39,12436,0.040367665,1.519813251,1.008430203,2.318808655,0.106368369,DB0064110036790_,2.240847029,0.418587466,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,29891,DB00682,10036790,168,19291,78,16286,8.42741519060548e-06,1.818302777,1.380828925,2.412140374,9.35647764667646e-05,DB0068210036790_,9.276856565,0.597903526,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,29892,DB00695,10036790,203,27846,100,20428,0.001060303,1.489207118,1.16554762,1.91293202,0.005784573,DB0069510036790_,5.152560717,0.398243843,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,29897,DB00254,10061428,58,5877,53,3335,0.013103608,0.621004122,0.419384463,0.921303616,0.044168804,DB0025410061428_,3.119736521,-0.47641756,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,doxycycline,DB00254
,29898,DB00343,10061428,175,8561,114,4981,0.355794736,0.893161874,0.69954853,1.144012676,0.525473046,DB0034310061428_,0.643456382,-0.112987445,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,diltiazem,DB00343
,29899,DB00480,10061428,954,66474,929,66733,0.5158914,1.030918681,0.940229653,1.130335673,0.67559502,DB0048010061428_,0.392161466,0.030450328,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,29900,DB00706,10061428,11,1064,339,15586,0.010356109,0.475335213,0.234284439,0.865052065,0.036607091,DB0070610061428_,3.307513313,-0.743735011,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,tamsulosin,DB00706
,29902,DB01275,10061428,72,3907,50,3299,0.314032273,1.21587682,0.83321685,1.786340874,0.481583331,DB0127510061428_,0.730675997,0.195465479,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,hydralazine,DB01275
,29912,DB00343,10017955,145,8591,112,4983,0.026350038,0.750960931,0.581292282,0.972195792,0.076525396,DB0034310017955_,2.570132618,-0.286401651,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,29915,DB00047,10051055,30,9255,74,8444,1.62501943553318e-06,0.369899956,0.233328011,0.573127606,2.21085071754605e-05,DB0004710051055_,10.71954808,-0.994522698,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,insulin glargine,DB00047
,29916,DB00175,10051055,49,8082,55,6051,0.046277046,0.66705504,0.443731463,1.000151682,0.118044752,DB0017510051055_,2.136691471,-0.404882717,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,pravastatin,DB00175
,29917,DB00196,10051055,51,5032,52,3233,0.025016138,0.630189177,0.418604609,0.948265913,0.073502033,DB0019610051055_,2.610442216,-0.461735224,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,fluconazole,DB00196
,29918,DB00343,10051055,42,8694,31,5064,0.331631584,0.789181376,0.483743842,1.300252182,0.500469997,DB0034310051055_,0.692207628,-0.236759104,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,diltiazem,DB00343
,29921,DB00047,10051398,14,9271,49,8469,1.53649316461029e-06,0.260991527,0.13297702,0.480849588,2.10402307016313e-05,DB0004710051398_,10.76907421,-1.343267335,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,insulin glargine,DB00047
,29922,DB00175,10051398,30,8101,39,6067,0.027528901,0.576126489,0.345202031,0.952786637,0.07916818,DB0017510051398_,2.536180835,-0.551428044,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pravastatin,DB00175
,29925,DB00646,10051398,24,3429,40,1960,3.50635331354183e-05,0.34302766,0.197167458,0.585082732,0.000325269,DB0064610051398_,8.030856719,-1.069944193,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,nystatin,DB00646
,29926,DB00682,10051398,18,19441,75,16289,6.64533207805042e-12,0.201122003,0.113060245,0.33999859,2.6266549424294e-10,DB0068210051398_,22.06013978,-1.603843576,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,warfarin,DB00682
,29929,DB06186,10051398,174,2035,310,3336,0.405776784,0.920128903,0.753533589,1.120891886,0.575350242,DB0618610051398_,0.552776308,-0.083241507,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ipilimumab,DB06186
,29931,DB00563,10022437,296,46350,79,15269,0.105019487,1.234302483,0.959293842,1.603952454,0.218553281,DB0056310022437_,1.520725445,0.210506019,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,29932,DB00563,10020642,140,46506,49,15299,0.735632688,0.939904809,0.674018018,1.330087961,0.847238699,DB0056310020642_,0.165772807,-0.061976676,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,29933,DB00864,10008479,46,6823,58,8334,0.921374285,0.96873942,0.642312525,1.453573769,0.965219524,DB0086410008479_,0.035399718,-0.031759619,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,29934,DB01015,10008479,93,9794,69,9312,0.13355122,1.281475344,0.927216454,1.778451414,0.260695393,DB0101510008479_,1.344402632,0.248012027,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,29937,DB00635,10033557,224,32829,49,23745,3.79298503714258e-17,3.306379816,2.416746843,4.603172006,2.967220586348e-15,DB0063510033557_,33.45115071,1.19585388,female,10033557,Palpitations,10007541,Cardiac disorders,Card,prednisone,DB00635
,29940,DB00465,10003988,54,2050,14,869,0.107923569,1.634810531,0.889774833,3.204555044,0.22295524,DB0046510003988_,1.500784244,0.491526914,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ketorolac,DB00465
,29942,DB00722,10003988,476,24927,373,25659,9.03495600919756e-05,1.313602487,1.143399633,1.510110995,0.000732071,DB0072210003988_,7.219633112,0.272773353,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,29943,DB00758,10003988,154,8146,168,9906,0.337475178,1.114711272,0.888079745,1.398439318,0.506656103,DB0075810003988_,0.679922803,0.108595423,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,clopidogrel,DB00758
,29944,DB01076,10003988,495,25252,376,25207,7.23703685239349e-05,1.31413215,1.145572227,1.508514833,0.000603891,DB0107610003988_,7.412117635,0.273176486,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,29948,DB00480,10022595,36,67392,60,67602,0.018408793,0.601875504,0.38663658,0.924985224,0.057877448,DB0048010022595_,2.849427475,-0.507704659,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,lenalidomide,DB00480
,29951,DB00904,10022595,43,23026,48,14408,0.006732862,0.560577456,0.362424011,0.8645861,0.025973916,DB0090410022595_,3.65066249,-0.578787856,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,ondansetron,DB00904
,29953,DB00030,10046571,61,2145,11,1810,1.10963082037109e-07,4.677851677,2.430224084,9.8908139,1.99430058895413e-06,DB0003010046571_,13.12521715,1.542838961,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,insulin human,DB00030
,29954,DB00213,10046571,466,18429,156,13265,6.21726555280229e-18,2.150073657,1.787206139,2.598156368,5.33183768533143e-16,DB0021310046571_,35.16766553,0.765502101,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,29955,DB00480,10046571,1187,66241,488,67174,1.4402601013569e-68,2.466716173,2.216693544,2.747939512,1.57738486517359e-65,DB0048010046571_,149.2122627,0.902887781,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,29956,DB00482,10046571,141,8118,22,3049,3.7888323045889e-05,2.406913996,1.525517573,3.97131225,0.00034852,DB0048210046571_,7.961816275,0.878345427,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,celecoxib,DB00482
,29958,DB00572,10046571,77,2825,19,2107,3.24676304246091e-06,3.021973837,1.804000144,5.306249896,4.05846368568837e-05,DB0057210046571_,10.11212097,1.105910206,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,atropine,DB00572
,29959,DB00722,10046571,553,24850,203,25829,8.12881204363848e-41,2.831421548,2.404089547,3.345033792,3.31264844289981e-38,DB0072210046571_,86.30048553,1.040778899,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,lisinopril,DB00722
,29960,DB01076,10046571,611,25136,277,25306,8.8133807623497e-30,2.220670568,1.921543445,2.57153775,1.92248724762126e-27,DB0107610046571_,61.51617772,0.797809208,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,29963,DB00213,10058080,68,18827,50,13371,0.852081858,0.965859297,0.660134998,1.421701957,0.927430036,DB0021310058080_,0.075337921,-0.034737111,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,29964,DB00331,10058080,55,24891,54,20698,0.38805669,0.846949606,0.570832757,1.257090388,0.558047899,DB0033110058080_,0.583310479,-0.166114083,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,metformin,DB00331
,29965,DB00381,10058080,46,29314,50,22837,0.122067919,0.716736588,0.469419287,1.092151479,0.24439618,DB0038110058080_,1.408964681,-0.333046886,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,29967,DB00480,10058080,75,67353,134,67528,5.37645499543333e-05,0.561161531,0.41713103,0.75013062,0.000469502,DB0048010058080_,7.663837875,-0.577746481,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,29970,DB00682,10058080,90,19369,64,16300,0.330915087,1.183424833,0.84882742,1.658155858,0.4996182,DB0068210058080_,0.693911072,0.168412635,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,29971,DB00695,10058080,81,27968,82,20446,0.039024133,0.722149617,0.524298144,0.994474023,0.103705322,DB0069510058080_,2.266201844,-0.325522935,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,29973,DB00904,10058080,77,22992,41,14415,0.448749065,1.177493105,0.795465456,1.765553046,0.616332384,DB0090410058080_,0.483968877,0.163387691,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,ondansetron,DB00904
,29974,DB01076,10058080,49,25698,66,25517,0.112736411,0.737202227,0.498547422,1.083651341,0.230194774,DB0107610058080_,1.468829483,-0.304893033,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,29976,DB06605,10003988,253,13820,144,12889,1.82808705343873e-06,1.638549044,1.328162372,2.027660767,2.4472252711809e-05,DB0660510003988_,10.61797062,0.493811121,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,29978,DB00399,10006451,89,6903,52,4946,0.264479795,1.226296465,0.859594472,1.765016064,0.426428549,DB0039910006451_,0.852310455,0.203998623,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,zoledronic acid,DB00399
,29979,DB01136,10006451,113,9771,60,11055,1.65630082606955e-06,2.130760019,1.542565108,2.968351851,2.24933439489734e-05,DB0113610006451_,10.70229112,0.756478732,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,carvedilol,DB01136
,29980,DB01234,10006451,265,31360,186,32702,3.7296504633751e-05,1.485681843,1.226278403,1.803030616,0.000343557,DB0123410006451_,7.976158822,0.39587382,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,29981,DB14500,10006451,137,7672,33,4040,2.04735959679924e-05,2.186021376,1.482488068,3.308202823,0.000203921,DB1450010006451_,8.497776127,0.782083168,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,potassium,DB14500
,29982,DB00399,10007559,44,6948,44,4954,0.128464186,0.713043114,0.457891774,1.11033988,0.25346131,DB0039910007559_,1.372544091,-0.338213392,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,zoledronic acid,DB00399
,29983,DB14500,10007559,106,7703,90,3983,0.00079627,0.609001487,0.45425932,0.818001125,0.004556926,DB1450010007559_,5.391107024,-0.49593457,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,potassium,DB14500
,29992,DB00804,10028813,231,2769,54,845,0.092950301,1.305319825,0.95634891,1.807943804,0.199999891,DB0080410028813_,1.609438459,0.266448088,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dicyclomine,DB00804
,29993,DB00804,10047700,136,2864,26,873,0.028640342,1.594205553,1.034073253,2.545439143,0.081694128,DB0080410047700_,2.504773154,0.466375526,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dicyclomine,DB00804
,29996,DB00682,10021789,205,19254,122,16242,0.002549885,1.417449196,1.126219306,1.790139391,0.01184209,DB0068210021789_,4.436095124,0.348858916,NA,10021789,Infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,29998,DB01175,10041349,169,10555,78,4814,0.944904843,0.988189461,0.749560053,1.312449783,0.98355868,DB0117510041349_,0.016577978,-0.011880837,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,29999,DB01175,10057668,55,10669,25,4867,1,1.003599386,0.614089389,1.682808844,1,DB0117510057668_,0,0.003592923,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,30002,DB00331,10027091,48,24898,54,20698,0.135718527,0.738954409,0.490044102,1.111334852,0.263702061,DB0033110027091_,1.332935368,-0.302519053,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,30011,DB00295,10013710,56,14607,97,9505,3.25596635696157e-09,0.37568498,0.265157661,0.527927323,8.16242972749022e-08,DB0029510013710_,16.32113886,-0.979004307,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,30012,DB00333,10013710,60,3011,151,3001,4.15514936453543e-10,0.396076655,0.287385044,0.540078651,1.23549888062007e-08,DB0033310013710_,18.2092059,-0.926147513,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,methadone,DB00333
,30017,DB00295,10047302,16,14647,46,9556,5.57103171584003e-08,0.22694302,0.11984519,0.40868423,1.06691853297527e-06,DB0029510047302_,13.75073594,-1.483056305,male,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,morphine,DB00295
,30019,DB06605,10013946,88,13985,51,12982,0.008124989,1.601704495,1.120821947,2.310049142,0.030166724,DB0660510013946_,3.501015806,0.471068372,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,30022,DB01042,10062355,33,957,30,1298,0.122500402,1.491664776,0.875232623,2.551369484,0.245028769,DB0104210062355_,1.40637965,0.399892796,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,melphalan,DB01042
,30023,DB06605,10015926,39,14034,20,13013,0.036098106,1.808087778,1.028626568,3.273868751,0.097717685,DB0660510015926_,2.325672727,0.592269811,NA,10015926,Eye haemorrhage,10015919,Eye disorders,Eye,apixaban,DB06605
,30024,DB00230,10017955,56,19618,43,8608,0.008291728,0.571446522,0.376876937,0.871824858,0.030640807,DB0023010017955_,3.485422595,-0.559584375,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,30025,DB00425,10017955,58,12637,71,7413,3.37946842283107e-05,0.479212653,0.332369167,0.688530757,0.000315053,DB0042510017955_,8.062768169,-0.735610827,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,30026,DB00451,10017955,311,46960,152,15267,5.89774825419301e-05,0.665190015,0.545660863,0.813700776,0.000508687,DB0045110017955_,7.583677987,-0.407682542,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,30027,DB06605,10017955,512,13561,564,12469,0.003779877,0.834708014,0.737263783,0.944852779,0.016295565,DB0660510017955_,4.116862277,-0.180673299,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,30037,DB06605,10008111,105,13968,155,12878,0.000220728,0.624572733,0.482230629,0.806310858,0.001565317,DB0660510008111_,6.459666759,-0.470687491,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,30043,DB00484,10053762,64,2443,37,1743,0.357950217,1.23404524,0.80659536,1.91237377,0.527690491,DB0048410053762_,0.639245358,0.210297586,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,brimonidine,DB00484
,30046,DB06605,10018985,177,13896,212,12821,0.012176476,0.770327608,0.626412742,0.9463471,0.041633647,DB0660510018985_,3.178846606,-0.260939389,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,30047,DB00343,10015090,88,8648,43,5052,0.363694257,1.195558774,0.819640375,1.767158394,0.533272169,DB0034310015090_,0.628723349,0.17861367,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,30048,DB00421,10015090,113,8790,50,5202,0.10258142,1.33746156,0.948805417,1.908608506,0.214900186,DB0042110015090_,1.537581612,0.290773459,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,30050,DB01050,10015090,81,18027,43,9328,0.924419175,0.974706076,0.664753874,1.446943314,0.967387599,DB0105010015090_,0.033156038,-0.025619314,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,30051,DB06605,10015090,253,13820,210,12823,0.241177897,1.117836549,0.925721526,1.350953628,0.399358334,DB0660510015090_,0.917896185,0.111395165,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,30052,DB00635,10019465,33,33020,24,23770,1,0.989815272,0.567343951,1.750633632,1,DB0063510019465_,0,-0.010236947,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,30056,DB01060,10011906,198,8389,206,4875,1.01242918208634e-08,0.558601715,0.455719978,0.684480912,2.27839906259754e-07,DB0106010011906_,15.29462262,-0.582318555,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,30057,DB00484,10010264,40,2467,24,1756,0.526434259,1.186263447,0.694989865,2.065300709,0.684278119,DB0048410010264_,0.379390838,0.170808406,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,brimonidine,DB00484
,30058,DB00722,10053762,603,24800,494,25538,0.000194173,1.256962964,1.112712436,1.420467236,0.001405244,DB0072210053762_,6.567544042,0.228698466,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,30060,DB01016,10013968,53,1048,44,1184,0.146585295,1.3606708,0.886788055,2.096671977,0.279151927,DB0101610013968_,1.275999105,0.307977813,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glyburide,DB01016
,30061,DB00421,10016322,201,8702,52,5200,1.18992789052635e-08,2.309688439,1.691485149,3.203156303,2.63268588955615e-07,DB0042110016322_,15.15009108,0.83711264,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,30062,DB00999,10016322,451,20979,142,12097,8.12403794627375e-11,1.83135904,1.511195033,2.23044634,2.68604198009818e-09,DB0099910016322_,19.73519711,0.605058336,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,30064,DB08932,10016322,601,18842,161,6436,0.006774437,1.275054122,1.067207304,1.530498733,0.026109395,DB0893210016322_,3.645460058,0.242988626,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,30065,DB00421,10022004,72,8831,11,5241,1.8277516077171e-06,3.884287768,2.0443296,8.132916885,2.4472252711809e-05,DB0042110022004_,10.61797062,1.356939638,female,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,30066,DB00999,10022004,142,21288,43,12196,0.000158723,1.8918843,1.335420153,2.729064251,0.001184229,DB0099910022004_,6.738663102,0.637573317,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,30068,DB08932,10022004,195,19248,59,6538,0.468972494,1.122637209,0.833800793,1.53102429,0.635343882,DB0893210022004_,0.453588881,0.115680569,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,30070,DB00421,10028810,152,8751,42,5210,4.16093682683718e-06,2.154530294,1.519153563,3.114574992,5.02620516973415e-05,DB0042110028810_,9.898260205,0.767572739,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,spironolactone,DB00421
,30071,DB00999,10028810,347,21083,114,12125,9.32561594319811e-08,1.75051956,1.410941699,2.185179517,1.69812133749195e-06,DB0099910028810_,13.28598801,0.559912635,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,30073,DB08932,10028810,754,18689,157,6440,3.3221636796607e-09,1.654932283,1.388261078,1.982758928,8.30067227375299e-08,DB0893210028810_,16.30434424,0.503760091,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,macitentan,DB08932
,30075,DB08932,10021789,275,19168,74,6523,0.082522116,1.264631165,0.973413117,1.660266549,0.182575972,DB0893210021789_,1.70058891,0.234780511,NA,10021789,Infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,30076,DB00060,10013573,179,9329,46,2419,1,1.009011212,0.723685606,1.431797216,1,DB0006010013573_,0,0.008970853,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,30077,DB00060,10047513,73,9435,22,2443,0.52487881,0.859160118,0.525985738,1.456957775,0.683008962,DB0006010047513_,0.381247298,-0.151799973,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,interferon beta-1a,DB00060
,30080,DB01076,10018867,30,25717,125,25458,2.65433506901066e-15,0.237604725,0.153840105,0.356389612,1.69548474578239e-13,DB0107610018867_,29.40563752,-1.437146806,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,30081,DB06605,10018867,70,14003,144,12889,1.79887933565281e-08,0.447449466,0.331017213,0.600054626,3.80781317645547e-07,DB0660510018867_,14.7810406,-0.804191673,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,apixaban,DB06605
,30082,DB06605,10000087,148,13925,82,12951,0.000149657,1.678594898,1.271656634,2.228797799,0.001124245,DB0660510000087_,6.790643144,0.517957073,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,30083,DB06605,10016100,41,14032,54,12979,0.099548037,0.702295916,0.455889605,1.074627796,0.210119663,DB0660510016100_,1.560078089,-0.353400432,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,30090,DB00635,10029444,63,32990,151,23643,3.32187449271486e-17,0.299014788,0.219105565,0.40396112,2.62602920424091e-15,DB0063510029444_,33.5733035,-1.20726225,male,10029444,Nocardiosis,10021881,Infections and infestations,Infec,prednisone,DB00635
,30095,DB00715,10022437,109,4734,51,2236,1,1.009483745,0.714558603,1.442400574,1,DB0071510022437_,0,0.009439056,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,paroxetine,DB00715
,30097,DB00811,10022998,25,2773,59,4097,0.056578306,0.626083581,0.374767071,1.018144362,0.13708446,DB0081110022998_,1.987158048,-0.4682714,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,ribavirin,DB00811
,30098,DB01224,10022998,55,8053,33,5884,0.388558707,1.217748342,0.775797647,1.93846785,0.558529237,DB0122410022998_,0.582448313,0.197003532,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,30099,DB08934,10022998,48,4441,56,6148,0.424678054,1.18658112,0.788221266,1.780333377,0.593458765,DB0893410022998_,0.521787545,0.171076164,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,sofosbuvir,DB08934
,30100,DB00715,10037844,107,4736,42,2245,0.329927203,1.207591426,0.834473019,1.775761696,0.498570572,DB0071510037844_,0.69601013,0.188627819,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,paroxetine,DB00715
,30101,DB06605,10003239,243,13830,160,12873,0.000747388,1.413633852,1.151410595,1.739420013,0.004322354,DB0660510003239_,5.4439551,0.346163589,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,30102,DB00060,10024855,78,9430,19,2446,0.899911232,1.064804299,0.637051679,1.866299311,0.956571579,DB0006010024855_,0.044399659,0.062791026,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,30103,DB00087,10006093,43,1326,8,739,0.002669317,2.994305519,1.382025053,7.413286391,0.012292044,DB0008710006093_,4.398803075,1.096712324,female,10006093,Bradycardia,10007541,Cardiac disorders,Card,alemtuzumab,DB00087
,30115,DB00316,10018838,135,65339,104,36849,0.018191884,0.732097267,0.562512062,0.955036319,0.057331537,DB0031610018838_,2.858904427,-0.311841896,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,30119,DB00316,10024855,471,65003,235,36718,0.125189987,1.132153935,0.965514124,1.330392098,0.248874323,DB0031610024855_,1.390807236,0.124121956,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,30121,DB00316,10025310,35,65439,23,36930,0.585812867,0.858789294,0.49320713,1.522524704,0.733155158,DB0031610025310_,0.310397924,-0.152231679,NA,10025310,Lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,30124,DB00316,10045285,64,65410,22,36931,0.043406368,1.642487431,0.997891478,2.801082376,0.112446294,DB0031610045285_,2.185279562,0.496211819,NA,10045285,Ulcer,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,30129,DB00316,10047895,1143,64331,731,36222,0.008133931,0.880407084,0.800931269,0.968235146,0.03019566,DB0031610047895_,3.500057069,-0.127370883,NA,10047895,Weight decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,30130,DB01229,10047895,115,5626,65,2644,0.258322193,0.831503476,0.605899804,1.149311288,0.419291024,DB0122910047895_,0.869190032,-0.1845198,NA,10047895,Weight decreased,10022891,Investigations,Inv,paclitaxel,DB01229
,30131,DB00316,10049438,172,65302,78,36875,0.113678556,1.245237816,0.947207132,1.6494127,0.23164903,DB0031610049438_,1.462531853,0.219326528,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,30136,DB08904,10060795,35,11575,15,3544,0.314550502,0.714430746,0.379671814,1.409726988,0.482167076,DB0890410060795_,0.729464594,-0.336269213,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,certolizumab pegol,DB08904
,30138,DB08904,10064355,56,11554,21,3538,0.420095366,0.816574231,0.485891475,1.421928567,0.589031223,DB0890410064355_,0.529276087,-0.202637457,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,certolizumab pegol,DB08904
,30142,DB01164,10016165,19,6505,39,7897,0.0642357,0.591452692,0.322478705,1.04966094,0.151063378,DB0116410016165_,1.890055811,-0.525173579,NA,10016165,Failure to thrive,10027433,Metabolism and nutrition disorders,Metab,calcium chloride,DB01164
,30146,DB06605,10018870,35,14038,70,12963,0.000171526,0.46172128,0.298342162,0.702919541,0.001267158,DB0660510018870_,6.670978439,-0.772793861,NA,10018870,Blood urine present,10022891,Investigations,Inv,apixaban,DB06605
,30147,DB00051,10005425,65,25666,13,11407,0.006510197,2.222160326,1.212498625,4.396653466,0.025274429,DB0005110005425_,3.677962101,0.798479842,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,adalimumab,DB00051
,30149,DB00736,10005425,33,10558,18,5535,0.883498896,0.961140702,0.525131593,1.814726772,0.951297336,DB0073610005425_,0.049928609,-0.039634469,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,esomeprazole,DB00736
,30153,DB01050,10005425,46,18062,12,9359,0.036586584,1.986234178,1.034819546,4.12095191,0.098745084,DB0105010005425_,2.315213662,0.686240473,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,ibuprofen,DB01050
,30156,DB08895,10005425,417,27697,64,6582,0.000848558,1.548362712,1.185969014,2.05026998,0.004806974,DB0889510005425_,5.337687486,0.437198058,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,tofacitinib,DB08895
,30158,DB00051,10014184,43,25688,27,11393,0.155760623,0.706336821,0.42640401,1.189385241,0.291804853,DB0005110014184_,1.231670013,-0.347663072,NA,10014184,Eczema,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,30169,DB00051,10023232,433,25298,156,11264,0.024375427,1.235830705,1.025373037,1.495840842,0.072123386,DB0005110023232_,2.629376937,0.21174338,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,30172,DB01075,10023232,96,19852,36,11061,0.045052521,1.485776799,1.002482283,2.245997185,0.11567331,DB0107510023232_,2.156985352,0.395937733,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,30173,DB01281,10023232,132,8800,26,1772,1,1.022308192,0.665131302,1.627726871,1,DB0128110023232_,0,0.022063004,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,abatacept,DB01281
,30174,DB08895,10023232,1160,26954,263,6383,0.55847167,1.044505536,0.910201545,1.202024907,0.711384921,DB0889510023232_,0.340541616,0.043543602,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,30176,DB00051,10025082,70,25661,26,11394,0.506595667,1.195419953,0.751882841,1.955279145,0.667330466,DB0005110025082_,0.404469905,0.178497548,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,30183,DB01075,10025082,36,19912,19,11078,0.889144898,1.054134836,0.588531755,1.946434567,0.953968782,DB0107510025082_,0.047124331,0.05272037,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,30185,DB08895,10025082,83,28031,17,6629,0.702365663,1.154613531,0.678944255,2.077469252,0.821450152,DB0889510025082_,0.196684022,0.143765683,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,30187,DB00586,10035664,177,6932,77,2728,0.480527682,0.904639457,0.685733902,1.202628368,0.645310893,DB0058610035664_,0.438023074,-0.100218804,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,diclofenac,DB00586
,30188,DB00852,10035664,35,1131,20,451,0.225566295,0.697997463,0.387163027,1.290623216,0.380345131,DB0085210035664_,0.966676199,-0.359539811,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pseudoephedrine,DB00852
,30190,DB01050,10035664,347,17761,226,9145,0.007489343,0.790590928,0.665374087,0.940754259,0.028263802,DB0105010035664_,3.566173367,-0.234974603,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,30191,DB01281,10035664,181,8751,51,1747,0.040368182,0.708532424,0.514282868,0.991037354,0.106368369,DB0128110035664_,2.240847029,-0.344559457,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,abatacept,DB01281
,30192,DB08906,10035664,131,2062,97,1061,0.00941629,0.694958721,0.524659832,0.923076803,0.03392394,DB0890610035664_,3.383634332,-0.363902829,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,fluticasone furoate,DB08906
,30193,DB00736,10037844,269,10322,128,5425,0.392090075,1.1045363,0.889205343,1.377817187,0.561985241,DB0073610037844_,0.576279691,0.099425609,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,esomeprazole,DB00736
,30194,DB00788,10037844,296,9060,141,4920,0.221942484,1.140023037,0.926750347,1.407590928,0.37594704,DB0078810037844_,0.978306996,0.13104847,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,naproxen,DB00788
,30195,DB00852,10037844,50,1116,11,460,0.061557901,1.872949923,0.951687375,4.026993988,0.146310646,DB0085210037844_,1.922023205,0.627514687,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,pseudoephedrine,DB00852
,30196,DB01047,10037844,46,741,26,454,0.803264161,1.083927877,0.645839624,1.853814558,0.893490882,DB0104710037844_,0.112619149,0.080591366,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,fluocinonide,DB01047
,30197,DB01050,10037844,494,17614,194,9177,0.000833367,1.326682495,1.119177786,1.577607392,0.004737766,DB0105010037844_,5.352189583,0.282681462,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,30198,DB01281,10037844,280,8652,57,1741,0.940920735,0.988475007,0.73738755,1.344721818,0.98012965,DB0128110037844_,0.02007042,-0.01159192,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,abatacept,DB01281
,30199,DB08906,10037844,68,2125,37,1121,0.917040999,0.969496658,0.635803259,1.498841771,0.963078997,DB0890610037844_,0.037619839,-0.030978251,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone furoate,DB08906
,30200,DB00005,10048694,73,128009,18,42401,0.331306145,1.343321296,0.793476505,2.391897778,0.500065005,DB0000510048694_,0.693017179,0.295145127,NA,10048694,Rheumatoid nodule,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,30223,DB01273,10025482,104,1936,25,1250,2.94202762052402e-06,2.685243683,1.710487232,4.364084665,3.72231990399393e-05,DB0127310025482_,10.19857836,0.987771481,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,varenicline,DB01273
,30224,DB01273,10047700,88,1952,39,1236,0.076910866,1.428603626,0.962144971,2.154786254,0.173030523,DB0127310047700_,1.754287264,0.356697482,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,varenicline,DB01273
,30225,DB00316,10046555,110,65364,109,36844,3.93764813261813e-05,0.5688786,0.432330387,0.748565728,0.000359816,DB0031610046555_,7.929917684,-0.564088224,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,30226,DB01075,10046555,35,19913,31,11066,0.07098382,0.627404712,0.375583772,1.052834007,0.163013011,DB0107510046555_,1.81392526,-0.466163472,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,diphenhydramine,DB01075
,30232,DB00331,10005169,42,24904,43,20709,0.383242016,0.812221548,0.51783824,1.273143048,0.553307502,DB0033110005169_,0.59184137,-0.207982134,NA,10005169,Blindness,10015919,Eye disorders,Eye,metformin,DB00331
,30236,DB00331,10049848,151,24795,122,20630,0.854934528,1.029801812,0.805189696,1.319229521,0.929630334,DB0033110049848_,0.072968262,0.029366368,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,metformin,DB00331
,30238,DB00158,10017944,73,16742,21,8083,0.035948794,1.678265234,1.020375041,2.873763621,0.097423862,DB0015810017944_,2.328684106,0.517760661,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,30239,DB00193,10017944,83,19237,23,8679,0.035790574,1.628080043,1.014831153,2.710002001,0.097080154,DB0019310017944_,2.332218316,0.487401433,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,30241,DB00588,10017944,81,16443,38,8430,0.698479294,1.092811442,0.733874847,1.653327524,0.81870806,DB0058810017944_,0.200027718,0.08875368,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,30242,DB00788,10017944,46,9310,13,5048,0.039663559,1.918520388,1.017983939,3.874646462,0.104990599,DB0078810017944_,2.253884469,0.651554258,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,30243,DB00999,10017944,92,21338,24,12215,0.000316402,2.194354627,1.386913196,3.598964364,0.002107873,DB0099910017944_,6.162075802,0.785887984,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,30245,DB08895,10017944,257,27857,45,6601,0.065871224,1.353290212,0.981600458,1.903789949,0.153911297,DB0889510017944_,1.871378839,0.302538821,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,30255,DB08895,10044016,47,28067,6,6640,0.165156012,1.853135744,0.790259862,5.306500722,0.304342453,DB0889510044016_,1.189601723,0.616879201,NA,10044016,Tooth abscess,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,30257,DB00983,10033371,78,3423,13,1727,6.5867731405321e-05,3.026660413,1.665001933,5.953883345,0.000557147,DB0098310033371_,7.492682007,1.107459838,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,formoterol,DB00983
,30258,DB00422,10002855,183,3252,97,2852,8.19527491317172e-05,1.654410727,1.279465177,2.149972368,0.00067327,DB0042210002855_,7.30336382,0.503444889,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,methylphenidate,DB00422
,30260,DB01255,10002855,106,2027,78,1500,1,1.005653034,0.737640144,1.37584062,1,DB0125510002855_,0,0.005637116,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,lisdexamfetamine,DB01255
,30263,DB00422,10013496,60,3375,67,2882,0.150230139,0.764746591,0.528646512,1.104162046,0.284321383,DB0042210013496_,1.257650051,-0.268210753,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,methylphenidate,DB00422
,30265,DB01255,10013496,108,2025,100,1478,0.097346124,0.788324742,0.589854379,1.054325893,0.206884127,DB0125510013496_,1.575596417,-0.237845165,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,lisdexamfetamine,DB01255
,30266,DB01018,10013709,37,375,120,659,0.001602105,0.54210452,0.356538408,0.808787827,0.008108102,DB0101810013709_,4.814891492,-0.612296454,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,guanfacine,DB01018
,30267,DB01255,10013709,391,1742,295,1283,0.797507262,0.976184705,0.822964215,1.158735531,0.890504605,DB0125510013709_,0.115967005,-0.024103463,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lisdexamfetamine,DB01255
,30271,DB01016,10003239,35,1066,15,1213,0.001409762,2.65403667,1.403191353,5.260541465,0.007298717,DB0101610003239_,4.920056691,0.976081753,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,glyburide,DB01016
,30272,DB00331,10037153,433,24513,231,20521,2.76258360958646e-08,1.569179512,1.333000513,1.851069088,5.6159713981423e-07,DB0033110037153_,14.39248108,0.450552879,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,30274,DB00331,10037162,125,24821,50,20702,5.99849575160682e-06,2.085057339,1.489844564,2.957019624,6.92752464108019e-05,DB0033110037162_,9.57742291,0.734796355,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,30280,DB01098,10047513,75,8074,42,7167,0.01971796,1.585062732,1.070781415,2.374305753,0.061111494,DB0109810047513_,2.79505531,0.460623985,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,rosuvastatin,DB01098
,30282,DB00005,10028694,67,128015,36,42383,0.022214124,0.616175943,0.404992119,0.951400949,0.067107028,DB0000510028694_,2.701466504,-0.484222734,NA,10028694,Nail disorder,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,30299,DB00264,10051398,82,29525,173,24719,1.16441274493031e-12,0.396839023,0.301132187,0.519361465,5.19195742162735e-11,DB0026410051398_,23.68132524,-0.924224565,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metoprolol,DB00264
,30301,DB00437,10051398,28,6893,82,11464,0.009890754,0.567916847,0.355551813,0.882772358,0.035251317,DB0043710051398_,3.34525239,-0.565780267,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,allopurinol,DB00437
,30302,DB00641,10051398,38,14086,72,12403,0.000110111,0.464728794,0.304891871,0.698380373,0.00086603,DB0064110051398_,7.051591377,-0.766301282,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,simvastatin,DB00641
,30303,DB09053,10007559,29,2256,72,3980,0.143280474,0.710610711,0.443655883,1.111578092,0.274429063,DB0905310007559_,1.293062473,-0.341630522,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,ibrutinib,DB09053
,30308,DB00332,10011224,110,2574,58,1598,0.332449213,1.177343676,0.843424619,1.657935181,0.501401628,DB0033210011224_,0.690347846,0.163260779,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipratropium,DB00332
,30309,DB00341,10011224,327,11078,135,4933,0.50628069,1.078602001,0.877376427,1.331873762,0.667113893,DB0034110011224_,0.404794493,0.075665759,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,30310,DB00425,10011224,196,12499,116,7368,1,0.996029839,0.78619495,1.266528227,1,DB0042510011224_,0,-0.003978063,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,30311,DB00646,10011224,100,3353,73,1927,0.128314184,0.787322835,0.573279614,1.085537646,0.253246608,DB0064610011224_,1.373391532,-0.239116905,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nystatin,DB00646
,30312,DB01104,10011224,245,15218,95,7191,0.113718895,1.218602175,0.956091453,1.563815028,0.23172225,DB0110410011224_,1.462215823,0.197704444,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,30313,DB01229,10011224,140,5601,48,2661,0.057637005,1.385654985,0.988185859,1.972196286,0.139008916,DB0122910011224_,1.973217201,0.326172941,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,paclitaxel,DB01229
,30314,DB05351,10011224,60,2663,10,1121,0.004967185,2.525234877,1.276694238,5.552754988,0.020353978,DB0535110011224_,3.894478927,0.926334079,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexlansoprazole,DB05351
,30315,DB00332,10035664,228,2456,142,1514,0.955391653,0.989792219,0.791117036,1.241514748,0.993161739,DB0033210035664_,0.006861749,-0.010260238,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ipratropium,DB00332
,30316,DB00341,10035664,372,11033,219,4849,0.000909247,0.7465418,0.627848075,0.889368683,0.005095853,DB0034110035664_,5.279328303,-0.29230367,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cetirizine,DB00341
,30317,DB00425,10035664,363,12332,297,7187,2.37214317287799e-05,0.712337742,0.607615459,0.835549497,0.000231018,DB0042510035664_,8.373014526,-0.339203124,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,zolpidem,DB00425
,30318,DB00646,10035664,202,3251,127,1873,0.478924228,0.916381205,0.724803198,1.16199059,0.644141393,DB0064610035664_,0.439837022,-0.087322838,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,nystatin,DB00646
,30319,DB01101,10035664,76,7513,42,3866,0.697259983,0.931142276,0.629246487,1.394488586,0.817898904,DB0110110035664_,0.201016539,-0.071343192,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,capecitabine,DB01101
,30320,DB01229,10035664,109,5632,126,2583,4.61293773574801e-12,0.396797159,0.302839396,0.519212028,1.87226882970508e-10,DB0122910035664_,22.39869996,-0.924330063,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,paclitaxel,DB01229
,30321,DB05351,10035664,62,2661,27,1104,0.814732814,0.952700919,0.593560219,1.566248908,0.900595148,DB0535110035664_,0.104699459,-0.048454256,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,dexlansoprazole,DB05351
,30326,DB00904,10035742,89,22980,65,14391,0.361828447,0.857475463,0.615343676,1.200310692,0.531574252,DB0090410035742_,0.631912389,-0.153762715,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,30329,DB01229,10035742,52,5689,39,2670,0.031513087,0.62579865,0.404149353,0.976160365,0.08804348,DB0122910035742_,2.429924492,-0.468726605,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,paclitaxel,DB01229
,30330,DB01234,10035742,68,31557,104,32784,0.014335008,0.679275927,0.492629024,0.931384115,0.047497252,DB0123410035742_,3.047083432,-0.386727862,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,30345,DB00007,10051398,13,1934,222,4230,8.11948277660181e-22,0.12809754,0.066994718,0.224373575,1.01147206058284e-19,DB0000710051398_,43.73771001,-2.054963275,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,leuprolide,DB00007
,30347,DB00788,10061822,50,9306,19,5042,0.207351582,1.425758868,0.824801627,2.56375038,0.358058481,DB0078810061822_,1.027058952,0.354704211,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,30349,DB06643,10038435,56,52365,29,7486,2.31171858473555e-07,0.27603833,0.173188463,0.448692933,3.87028808915758e-06,DB0664310038435_,12.46218161,-1.287215546,male,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,denosumab,DB06643
,30352,DB06643,10013950,131,52290,21,7494,0.623400401,0.894045314,0.560840327,1.493667987,0.763455716,DB0664310013950_,0.269900157,-0.111998819,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,30353,DB06643,10048334,375,52046,27,7488,0.000196639,1.998211218,1.350207929,3.075291849,0.001420744,DB0664310048334_,6.556574273,0.69225239,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,30354,DB01409,10030124,121,5910,53,3913,0.012286926,1.511521882,1.08282577,2.134534976,0.041945821,DB0140910030124_,3.171376466,0.413117012,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,30355,DB01409,10035598,53,5978,32,3934,0.739444288,1.089951166,0.688501358,1.750354464,0.85016024,DB0140910035598_,0.16233043,0.086132894,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,30356,DB01409,10047899,101,5930,45,3921,0.032776442,1.484001602,1.031912407,2.163472743,0.090782801,DB0140910047899_,2.399285425,0.394742224,NA,10047899,Weight increased,10022891,Investigations,Inv,tiotropium,DB01409
,30360,DB00115,10051398,49,18376,72,10400,2.01848177683437e-07,0.385176032,0.262090335,0.561899451,3.42185059684562e-06,DB0011510051398_,12.58532904,-0.954054823,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyanocobalamin,DB00115
,30361,DB00158,10051398,34,16781,49,8055,7.96262406545995e-07,0.333082246,0.208336554,0.526944755,1.17187891131363e-05,DB0015810051398_,11.3543171,-1.099365834,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,folic acid,DB00158
,30362,DB00169,10051398,115,38576,121,18054,1.0329049828443e-09,0.444804469,0.341375867,0.579363828,2.86240458345412e-08,DB0016910051398_,17.36901871,-0.810120489,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cholecalciferol,DB00169
,30363,DB00295,10051398,81,14582,133,9469,3.02978385516249e-11,0.39548981,0.295855378,0.525909664,1.0740103659197e-09,DB0029510051398_,20.65186619,-0.927630257,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,morphine,DB00295
,30365,DB00863,10051398,31,10642,32,5808,0.012033604,0.528710604,0.311702988,0.895816942,0.041236332,DB0086310051398_,3.188435573,-0.63731406,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ranitidine,DB00863
,30366,DB06643,10051398,63,52358,123,7392,4.22733275634506e-65,0.072318312,0.052457274,0.098854879,4.4446176600212e-62,DB0664310051398_,141.2685819,-2.626677899,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,denosumab,DB06643
,30367,DB06724,10051398,32,7897,55,3864,1.27355742369566e-08,0.284699264,0.177834692,0.448939094,2.7956321983479e-07,DB0672410051398_,15.09003738,-1.256321869,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,calcium carbonate,DB06724
,30371,DB00115,10050819,39,18386,19,10453,0.682058983,1.166956644,0.657925814,2.139263139,0.807727709,DB0011510050819_,0.213530271,0.154399201,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,30372,DB00169,10050819,78,38613,34,18141,0.761676171,1.07781014,0.711503986,1.664099937,0.867966655,DB0016910050819_,0.141601982,0.074931334,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,30373,DB00213,10050819,37,18858,21,13400,0.427572356,1.251954224,0.713538461,2.252248897,0.596136201,DB0021310050819_,0.517286113,0.22470571,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,30378,DB00451,10050819,75,47196,25,15394,0.907757075,0.978514575,0.614747568,1.606969773,0.958771936,DB0045110050819_,0.042102046,-0.021719597,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,30401,DB00996,10039897,115,38838,107,22318,0.000453271,0.617642237,0.470256961,0.811704781,0.002846206,DB0099610039897_,5.861768515,-0.481845893,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,30402,DB00996,10061822,380,38573,164,22261,0.001734225,1.337208077,1.109706438,1.617132914,0.008643175,DB0099610061822_,4.750985331,0.290583916,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,30403,DB00295,10011906,1007,13656,955,8647,1.58588707039725e-17,0.66771214,0.608027423,0.733269998,1.30062532434919e-15,DB0029510011906_,34.27593123,-0.403898126,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,30404,DB00502,10011906,50,1344,65,1807,0.923592011,1.034232635,0.695685332,1.529710923,0.966752923,DB0050210011906_,0.033812325,0.033659736,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,haloperidol,DB00502
,30405,DB00646,10011906,169,3284,132,1868,0.009652045,0.728326647,0.572323626,0.928342129,0.034597119,DB0064610011906_,3.363984866,-0.317005641,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,30406,DB01174,10011906,31,908,25,767,0.892388776,1.047427765,0.592774388,1.867630306,0.955096839,DB0117410011906_,0.045942542,0.046337411,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,phenobarbital,DB01174
,30407,DB11365,10011906,103,1542,127,1421,0.039733647,0.747455533,0.564846951,0.987257422,0.105139065,DB1136510011906_,2.252471379,-0.291080463,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sennosides,DB11365
,30421,DB00997,10035742,43,5288,45,3469,0.036883742,0.62691089,0.402014047,0.976367883,0.099353265,DB0099710035742_,2.30907345,-0.46695087,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxorubicin,DB00997
,30426,DB00153,10000087,99,7324,29,3410,0.027815062,1.589374852,1.039240624,2.499423992,0.079809504,DB0015310000087_,2.528112679,0.463340764,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,30427,DB00706,10000087,14,1061,126,15799,0.079762988,1.654447917,0.876152014,2.893039687,0.178037545,DB0070610000087_,1.725760822,0.503467369,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,tamsulosin,DB00706
,30428,DB01067,10000087,43,4318,47,4776,1,1.0119343,0.651875013,1.567370861,1,DB0106710000087_,0,0.011863648,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,glipizide,DB01067
,30431,DB00153,10003988,212,7211,68,3371,0.007497937,1.457391293,1.100448397,1.950677847,0.028284361,DB0015310003988_,3.565446236,0.376648052,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,30432,DB01067,10003988,75,4286,58,4765,0.043962149,1.437552017,1.004168004,2.066945862,0.113523789,DB0106710003988_,2.175742867,0.362941679,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,glipizide,DB01067
,30445,DB00706,10013573,26,1049,583,15342,0.033641282,0.652280405,0.420386296,0.971329261,0.092675272,DB0070610013573_,2.378653599,-0.427280741,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,30446,DB08899,10013573,6,243,372,7761,0.120029836,0.515143005,0.185974982,1.148702475,0.241428239,DB0889910013573_,1.421182995,-0.663310737,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,enzalutamide,DB08899
,30449,DB00153,10028813,512,6911,144,3295,1.60231536720956e-08,1.695128591,1.399475357,2.063477866,3.428315785682e-07,DB0015310028813_,14.88602653,0.527758603,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,30450,DB00706,10028813,52,1023,558,15367,0.027307362,1.399812917,1.025304184,1.876719103,0.078677411,DB0070610028813_,2.542399189,0.336338597,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,tamsulosin,DB00706
,30451,DB08899,10028813,22,227,420,7713,0.019768654,1.779640557,1.081484971,2.797556207,0.061236117,DB0889910028813_,2.79301812,0.576411409,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,enzalutamide,DB08899
,30453,DB00338,10033425,876,32798,361,21911,4.3769682634068e-15,1.621091247,1.43071372,1.839845792,2.7059018865022e-13,DB0033810033425_,28.93817094,0.483099532,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,30454,DB00706,10033425,24,1051,270,15655,0.183830872,1.324004026,0.829756895,2.023861017,0.328740652,DB0070610033425_,1.112486131,0.280660498,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,tamsulosin,DB00706
,30455,DB01067,10033425,112,4249,71,4752,0.000176894,1.764079534,1.294792142,2.417038127,0.001299386,DB0106710033425_,6.645863541,0.567629044,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,glipizide,DB01067
,30458,DB00338,10034568,34,33640,21,22251,0.890711852,1.070919559,0.603720919,1.942340309,0.954671384,DB0033810034568_,0.046388098,0.06851768,NA,10034568,Peripheral coldness,10047065,Vascular disorders,Vasc,omeprazole,DB00338
,30460,DB00451,10034568,43,47228,10,15409,0.424855806,1.402924677,0.693987063,3.131681816,0.593612484,DB0045110034568_,0.521528556,0.338559112,NA,10034568,Peripheral coldness,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,30466,DB00153,10047513,64,7359,26,3413,0.649338304,1.141606192,0.711922798,1.880197184,0.784206268,DB0015310047513_,0.243083196,0.132436211,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ergocalciferol,DB00153
,30467,DB00451,10047513,434,46837,93,15326,0.000135176,1.52697486,1.217101485,1.933009777,0.001030779,DB0045110047513_,6.877440709,0.423288563,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,levothyroxine,DB00451
,30468,DB00706,10047513,10,1065,97,15828,0.225919313,1.532097925,0.71009092,2.951571417,0.380806025,DB0070610047513_,0.965465155,0.426637989,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,tamsulosin,DB00706
,30469,DB01067,10047513,38,4323,33,4790,0.34050323,1.275870853,0.777597609,2.103236851,0.509702862,DB0106710047513_,0.673927346,0.243628968,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,glipizide,DB01067
,30481,DB00390,10061428,101,4044,87,3214,0.603203928,0.922660146,0.68307463,1.248390993,0.746936225,DB0039010061428_,0.291775473,-0.080494319,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,digoxin,DB00390
,30483,DB00028,10017918,55,13403,23,5592,1,0.997700174,0.602346643,1.702753015,1,DB0002810017918_,0,-0.002302475,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,30486,DB00588,10017918,55,16469,17,8451,0.080033592,1.660146903,0.948478161,3.053220398,0.178452133,DB0058810017918_,1.723434878,0.506906094,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,30490,DB00177,10000059,105,4695,34,2816,0.00138966,1.85214505,1.243375134,2.821361795,0.007216676,DB0017710000059_,4.931360853,0.616344454,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,valsartan,DB00177
,30492,DB00476,10000059,208,17049,65,6112,0.36914661,1.14717788,0.862968736,1.542453264,0.538772239,DB0047610000059_,0.61846236,0.137304909,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,30493,DB00480,10000059,413,67015,333,67329,0.002925904,1.246046756,1.075484752,1.444506389,0.013239351,DB0048010000059_,4.324561777,0.219975944,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,30495,DB01067,10000059,67,4294,52,4771,0.064196645,1.431524101,0.9791908,2.102996939,0.150998551,DB0106710000059_,1.890485039,0.358739682,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,glipizide,DB01067
,30507,DB00005,10042458,53,128029,28,42391,0.052977511,0.626736076,0.389276277,1.029232697,0.130605315,DB0000510042458_,2.035575365,-0.467229758,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,30508,DB00005,10061394,175,127907,35,42384,0.005079213,1.656763235,1.147087157,2.455515302,0.020712597,DB0000510061394_,3.877013237,0.504865841,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,30512,DB01267,10044565,47,2805,51,3664,0.411553675,1.203749432,0.789780582,1.831296707,0.580987049,DB0126710044565_,0.543026813,0.185441212,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,paliperidone,DB01267
,30515,DB00864,10003239,59,6810,51,8341,0.082960191,1.41689729,0.956069113,2.106040912,0.183352276,DB0086410003239_,1.696345972,0.348469474,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tacrolimus,DB00864
,30516,DB06285,10003239,507,8343,42,1064,0.006409419,1.539433697,1.114424681,2.17643761,0.024951359,DB0628510003239_,3.690826988,0.43141462,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,teriparatide,DB06285
,30517,DB06285,10012735,197,8653,15,1091,0.060113789,1.655824797,0.975078718,3.026484463,0.143690352,DB0628510012735_,1.940094628,0.504299251,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,teriparatide,DB06285
,30521,DB06285,10028836,57,8793,6,1100,0.841482495,1.188466201,0.511965872,3.381169576,0.919128483,DB0628510028836_,0.084329359,0.172663569,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,teriparatide,DB06285
,30525,DB08917,10046735,82,834,7,187,0.012555961,2.62496036,1.191511126,6.843291406,0.042689617,DB0891710046735_,3.153799555,0.965065795,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,ferric carboxymaltose,DB08917
,30528,DB00005,10034829,86,127996,26,42393,0.743699064,1.095525202,0.699354636,1.770711323,0.853481047,DB0000510034829_,0.158431943,0.091233885,NA,10034829,Pharyngeal oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,30535,DB00555,10070863,699,6348,418,3068,0.001390746,0.808235163,0.709466369,0.921517063,0.007221604,DB0055510070863_,4.930678151,-0.21290222,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,lamotrigine,DB00555
,30537,DB00987,10012735,90,2014,109,2819,0.340610769,1.155680239,0.859052075,1.551537704,0.509820287,DB0098710012735_,0.673696993,0.144689123,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cytarabine,DB00987
,30540,DB01060,10013950,44,8543,20,5061,0.365574863,1.303288251,0.75115777,2.337081858,0.535178795,DB0106010013950_,0.625154391,0.264890494,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,30541,DB01156,10013950,70,13552,23,6305,0.179679913,1.415964595,0.872096125,2.379316563,0.323452145,DB0115610013950_,1.128704104,0.347810992,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,30544,DB00787,10028411,110,16890,97,17151,0.329340529,1.151538869,0.867661176,1.530325486,0.497998953,DB0078710028411_,0.697157304,0.141099195,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,30546,DB01060,10028411,80,8507,39,5042,0.341804294,1.215712119,0.81773836,1.834502938,0.511024735,DB0106010028411_,0.671337285,0.195330011,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,amoxicillin,DB01060
,30560,DB00787,10068319,86,16914,53,17195,0.004855298,1.649564588,1.157235725,2.370318758,0.019989554,DB0078710068319_,3.912545424,0.500511367,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,30562,DB01060,10068319,60,8527,33,5048,0.829644401,1.076369932,0.691440206,1.702102828,0.910634524,DB0106010068319_,0.093613644,0.073594205,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amoxicillin,DB01060
,30563,DB01156,10068319,85,13537,11,6317,4.67302532972774e-06,3.605456973,1.915044593,7.502001099,5.57686587023354e-05,DB0115610068319_,9.794298518,1.282448524,female,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,30573,DB00273,10022437,161,8320,40,2153,0.860547618,1.041577705,0.730135826,1.516930735,0.934380954,DB0027310022437_,0.06787105,0.040736588,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,30574,DB00776,10022437,42,1863,26,1313,0.709096728,1.138405347,0.678047807,1.944557559,0.826380878,DB0077610022437_,0.190699501,0.129628465,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,oxcarbazepine,DB00776
,30576,DB00169,10005802,50,38641,28,18147,0.466998372,0.838643255,0.51767497,1.38395081,0.633535099,DB0016910005802_,0.456439876,-0.175969866,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,30579,DB00722,10005802,57,25346,37,25995,0.030256089,1.579962904,1.026201406,2.459384612,0.08524829,DB0072210005802_,2.462187223,0.457401369,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,lisinopril,DB00722
,30582,DB00169,10005956,76,38615,16,18159,0.0023306,2.233696623,1.290489976,4.105402349,0.011019936,DB0016910005956_,4.508049269,0.803657892,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,30583,DB00338,10005956,46,33628,17,22255,0.039389209,1.790730705,1.006927647,3.332759025,0.104427389,DB0033810005956_,2.259263287,0.582623752,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,30589,DB00169,10008190,277,38414,157,18018,0.062802358,0.827575078,0.677414751,1.013898888,0.148663029,DB0016910008190_,1.906073087,-0.189255447,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,30590,DB00555,10008190,37,7010,24,3462,0.339298915,0.761425501,0.442732437,1.332669999,0.508363324,DB0055510008190_,0.676558882,-0.272562943,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,30592,DB00783,10008190,108,16606,6,367,0.038894599,0.397841136,0.175286373,1.115253941,0.103418595,DB0078310008190_,2.268970495,-0.92170251,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,estradiol,DB00783
,30593,DB00555,10022437,126,6921,70,3416,0.443868998,0.888441598,0.656127623,1.211207231,0.611877887,DB0055510022437_,0.491222548,-0.118286364,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,30594,DB13961,10022437,185,9272,119,6295,0.679742312,1.055476976,0.831871912,1.343402841,0.80629196,DB1396110022437_,0.215309369,0.053992775,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,fish oil,DB13961
,30595,DB00169,10024855,248,38443,136,18039,0.153364105,0.85568658,0.690858659,1.063459064,0.288683437,DB0016910024855_,1.242424566,-0.155851115,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,30596,DB00555,10024855,71,6976,25,3461,0.156887534,1.408964911,0.880196641,2.324647225,0.293326507,DB0055510024855_,1.226468932,0.342855329,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,30597,DB00564,10024855,35,2569,18,1445,0.885603666,1.09368976,0.600330953,2.05918421,0.952411128,DB0056410024855_,0.04875848,0.089557081,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,carbamazepine,DB00564
,30598,DB00722,10024855,159,25244,168,25864,0.824414872,0.969667392,0.775129244,1.212625149,0.906981582,DB0072210024855_,0.097633136,-0.030802162,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,30600,DB13961,10024855,60,9397,35,6379,0.529767255,1.163669105,0.753581427,1.82181331,0.687006379,DB1396110024855_,0.375411701,0.151578035,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,30602,DB00338,10029202,36,33638,14,22258,0.111030415,1.701475972,0.895322814,3.416046683,0.227643528,DB0033810029202_,1.479974348,0.531496093,NA,10029202,Nervous system disorder,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,30615,DB00338,10061394,69,33605,19,22253,0.000421958,2.404760215,1.429848095,4.233912857,0.002677108,DB0033810061394_,5.923017988,0.877450196,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,30618,DB00722,10061394,53,25350,16,26016,4.89431047855495e-06,3.399760717,1.913098996,6.372652047,5.80405824176931e-05,DB0072210061394_,9.754368095,1.223705052,female,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,30621,DB00169,10061599,79,38612,18,18157,0.004348005,2.06381853,1.22492161,3.661296498,0.018274065,DB0016910061599_,4.002272424,0.724557922,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,30622,DB00338,10061599,62,33612,18,22254,0.001282504,2.280473611,1.331191838,4.097902507,0.00675141,DB0033810061599_,4.998003932,0.824383146,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,30625,DB00722,10061599,33,25370,18,26014,0.0348127,1.879836134,1.027870414,3.546574941,0.09505807,DB0072210061599_,2.353267315,0.63118461,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,30632,DB00678,10028596,117,15482,139,10585,1.24591773092796e-05,0.575514727,0.445558311,0.742265305,0.000131575,DB0067810028596_,8.935935662,-0.552490461,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,losartan,DB00678
,30642,DB00635,10021519,77,32976,49,23745,0.527771231,1.131496142,0.780466631,1.654291634,0.685267862,DB0063510021519_,0.377945478,0.123540776,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,30643,DB08910,10060933,43,16701,43,17445,0.914089205,1.04456244,0.667940186,1.633498616,0.961536643,DB0891010060933_,0.039222604,0.04359808,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,30648,DB00319,10005483,51,1341,69,1784,1,0.983306546,0.666078406,1.443575635,1,DB0031910005483_,0,-0.01683436,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,piperacillin,DB00319
,30649,DB00512,10005483,103,4634,158,4940,0.004661331,0.694974067,0.535031134,0.899486535,0.019322361,DB0051210005483_,3.946492234,-0.363880747,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,vancomycin,DB00512
,30650,DB01413,10005483,27,1193,44,1615,0.468792165,0.830751046,0.49160479,1.380662458,0.635197796,DB0141310005483_,0.453818838,-0.185425113,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,cefepime,DB01413
,30653,DB00512,10007882,46,4691,48,5050,0.917587984,1.031679664,0.67189423,1.582464908,0.963386915,DB0051210007882_,0.037300167,0.031188216,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,vancomycin,DB00512
,30656,DB00319,10038435,15,1377,37,1816,0.047212151,0.534752701,0.271496339,1.002958096,0.119854136,DB0031910038435_,2.121479812,-0.625950881,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,piperacillin,DB00319
,30657,DB00512,10038435,58,4679,103,4995,0.001883698,0.601169882,0.426968536,0.839525124,0.009268626,DB0051210038435_,4.681120146,-0.508877718,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,vancomycin,DB00512
,30658,DB01413,10038435,19,1201,53,1606,0.005303904,0.479498168,0.266604718,0.828488331,0.021446521,DB0141310038435_,3.842192828,-0.735015205,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,cefepime,DB01413
,30660,DB00588,10069327,230,16294,113,8355,0.730732776,1.043682114,0.828336795,1.321235143,0.843350648,DB0058810069327_,0.170372454,0.042754955,NA,10069327,Product quality issue,10077536,Product issues,Prod,fluticasone propionate,DB00588
,30665,DB06228,10018829,34,15878,47,16029,0.181988791,0.730293653,0.455219696,1.160469957,0.32635684,DB0622810018829_,1.119763895,-0.314308562,NA,10018829,Haemarthrosis,10028395,Musculoskeletal and connective tissue disorders,Musc,rivaroxaban,DB06228
,30667,DB01076,10038063,84,25663,102,25481,0.186140731,0.817693646,0.604856441,1.102896448,0.331607925,DB0107610038063_,1.103801958,-0.201267529,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,30670,DB00758,10002034,209,8091,311,9763,0.022553433,0.810909301,0.67550913,0.971901345,0.067849396,DB0075810002034_,2.690464788,-0.209599067,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,clopidogrel,DB00758
,30671,DB01104,10002034,205,15258,77,7209,0.094858427,1.257835907,0.961897648,1.659166783,0.203012548,DB0110410002034_,1.594487491,0.22939271,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,sertraline,DB01104
,30680,DB00169,10005724,193,38498,66,18109,0.027322288,1.375555959,1.034443583,1.84885961,0.078703159,DB0016910005724_,2.542071981,0.318857983,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,30682,DB00331,10005724,85,24861,39,20713,0.002015418,1.815802211,1.228426112,2.726736427,0.009787266,DB0033110005724_,4.626673113,0.596527359,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,metformin,DB00331
,30683,DB00399,10005724,65,6927,22,4976,0.002062137,2.12225574,1.289178395,3.620440902,0.009971167,DB0039910005724_,4.608057671,0.752479551,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,zoledronic acid,DB00399
,30684,DB00758,10005724,31,8269,20,10054,0.033557588,1.884502611,1.039592414,3.491049283,0.092478634,DB0075810005724_,2.380777646,0.633663919,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,clopidogrel,DB00758
,30686,DB00177,10012735,306,4494,134,2716,0.002289261,1.380052239,1.116266712,1.713300314,0.010861593,DB0017710012735_,4.52252226,0.322121352,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,valsartan,DB00177
,30687,DB00758,10012735,421,7879,403,9671,0.00050842,1.282237902,1.112207145,1.478466144,0.003131167,DB0075810012735_,5.76634966,0.248606912,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,30696,DB00169,10019304,70,38621,24,18151,0.222941055,1.370798422,0.851085759,2.280099018,0.377152414,DB0016910019304_,0.975105893,0.31539336,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,cholecalciferol,DB00169
,30698,DB00264,10019304,87,29520,53,24839,0.07408509,1.381203958,0.970073802,1.982792063,0.168359193,DB0026410019304_,1.78165553,0.322955552,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,metoprolol,DB00264
,30702,DB00999,10019304,38,21392,18,12221,0.57940357,1.206010089,0.671282526,2.245993287,0.728091307,DB0099910019304_,0.317328816,0.187317464,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,30706,DB01104,10044390,37,15426,16,7270,0.883126505,1.089834136,0.591062858,2.099836854,0.951117766,DB0110410044390_,0.050117391,0.086025516,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,30715,DB04868,10028411,48,1593,40,1476,0.665877263,1.11181614,0.710932598,1.747004216,0.796767144,DB0486810028411_,0.227192808,0.10599484,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,nilotinib,DB04868
,30716,DB04868,10033425,48,1593,37,1479,0.441734665,1.204386745,0.76325942,1.913863317,0.609894929,DB0486810033425_,0.494468584,0.185970512,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,nilotinib,DB04868
,30719,DB00684,10038540,30,2762,31,2317,0.439820172,0.811860257,0.47319715,1.391118699,0.608136413,DB0068410038540_,0.497356058,-0.208427051,NA,10038540,Renal tubular necrosis,10038359,Renal and urinary disorders,Renal,tobramycin,DB00684
,30720,DB00343,10011906,557,8179,382,4713,0.012818816,0.840230769,0.732623184,0.964397303,0.043403655,DB0034310011906_,3.13721162,-0.174078699,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,30721,DB00343,10040070,30,8706,20,5075,0.660985074,0.874409743,0.47984028,1.626267757,0.793151914,DB0034310040070_,0.231740507,-0.1342062,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,diltiazem,DB00343
,30722,DB00480,10040070,103,67325,129,67533,0.100347905,0.80091937,0.611941799,1.04604547,0.211341268,DB0048010040070_,1.554281069,-0.221994998,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,30724,DB00695,10040070,137,27912,109,20419,0.518233087,0.919472255,0.709256235,1.194382366,0.677547648,DB0069510040070_,0.3892754,-0.083955409,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,furosemide,DB00695
,30725,DB01234,10040070,126,31499,230,32658,2.18773649543841e-07,0.567991162,0.453160157,0.709292469,3.67676814466742e-06,DB0123410040070_,12.51347641,-0.56564942,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,30731,DB01164,10028813,173,6351,93,7843,5.71220683530257e-11,2.297106903,1.771104247,2.995000252,1.93986248922388e-09,DB0116410028813_,20.06064875,0.831650463,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,calcium chloride,DB01164
,30733,DB01164,10047700,155,6369,124,7812,0.000513396,1.533141537,1.199920922,1.962249585,0.003154737,DB0116410047700_,5.758850047,0.427318922,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,calcium chloride,DB01164
,30735,DB01164,10072608,20,6504,32,7904,0.402600915,0.759547763,0.411280235,1.370941221,0.572378805,DB0116410072608_,0.55795426,-0.275032071,NA,10072608,Inadequate aseptic technique in use of product,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium chloride,DB01164
,30739,DB00688,10053762,1065,5425,715,4663,2.25934179948882e-06,1.280262835,1.154161974,1.420674557,2.95016389466287e-05,DB0068810053762_,10.43106474,0.247065397,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,mycophenolate mofetil,DB00688
,30740,DB00480,10019301,88,67340,100,67562,0.422286635,0.882902404,0.65519693,1.187969684,0.591327271,DB0048010019301_,0.525385657,-0.124540613,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,30741,DB00480,10024855,338,67090,328,67334,0.669362269,1.034243892,0.885488147,1.208079619,0.799260087,DB0048010024855_,0.224068871,0.03367062,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,30742,DB00273,10013968,219,8262,38,2155,0.019057694,1.503149891,1.057492875,2.18839162,0.059490644,DB0027310013968_,2.821936216,0.407562834,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,topiramate,DB00273
,30743,DB00321,10013968,211,7236,75,2775,0.638958464,1.078902335,0.822003475,1.428921812,0.776038407,DB0032110013968_,0.253553266,0.075944168,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amitriptyline,DB00321
,30744,DB01068,10013968,401,13362,164,6676,0.03324989,1.221601634,1.013649411,1.477612982,0.09181357,DB0106810013968_,2.387995174,0.200162813,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,30747,DB00115,10047700,595,17830,178,10294,1.46221995899504e-15,1.929834982,1.626534991,2.298762293,9.64478083367243e-14,DB0011510047700_,29.96977438,0.657434498,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,30749,DB00571,10003239,96,5027,33,2576,0.048845615,1.490641929,0.991085832,2.293054212,0.122820777,DB0057110003239_,2.097029087,0.399206852,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,propranolol,DB00571
,30750,DB00571,10003549,114,5009,60,2549,0.871211649,0.966912531,0.6985034,1.34988739,0.943115942,DB0057110003549_,0.058566054,-0.033647242,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,30751,DB01217,10003549,108,2646,7,261,0.400638416,1.521684923,0.703469821,3.916146946,0.570511188,DB0121710003549_,0.561222499,0.419818223,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,anastrozole,DB01217
,30752,DB00169,10016334,155,38536,31,18144,2.76880404178275e-06,2.354131997,1.592163897,3.584356297,3.52863099337016e-05,DB0016910016334_,10.25201549,0.856172081,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,30753,DB00213,10016334,64,18831,26,13395,0.017944522,1.750924637,1.093401538,2.879892299,0.056728819,DB0021310016334_,2.869472923,0.560144012,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,30754,DB00451,10016334,173,47098,25,15394,4.40547568299162e-05,2.261629322,1.480984781,3.593416958,0.000396908,DB0045110016334_,7.831805875,0.816085492,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,30757,DB00169,10033557,300,38391,56,18119,3.03814969881256e-12,2.528317625,1.894331965,3.428224212,1.26157606371703e-10,DB0016910033557_,22.79348915,0.927554111,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,30758,DB00213,10033557,148,18747,52,13369,5.02218062194334e-06,2.029616398,1.469270499,2.842606825,5.94764666131024e-05,DB0021310033557_,9.729929843,0.707846809,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,30759,DB00571,10033557,40,5083,12,2597,0.10772412,1.70295608,0.874031881,3.572630321,0.222691978,DB0057110033557_,1.501965727,0.532365612,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,propranolol,DB00571
,30761,DB00982,10002368,13,3351,44,2057,2.97896312502161e-09,0.181419478,0.089409864,0.34393405,7.52542486700559e-08,DB0098210002368_,16.40239347,-1.706943371,male,10002368,Anger,10037175,Psychiatric disorders,Psych,isotretinoin,DB00982
,30765,DB00588,10061422,25,16499,39,8429,1.37206235840547e-05,0.327502526,0.189817525,0.555422259,0.00014337,DB0058810061422_,8.850083643,-1.11625951,male,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,30769,DB00169,10008629,88,38603,45,18130,0.642344795,0.918435638,0.633957949,1.346873411,0.778832076,DB0016910008629_,0.24995982,-0.08508345,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,cholecalciferol,DB00169
,30770,DB00264,10008629,60,29547,48,24844,0.846911829,1.051047766,0.706810877,1.570296063,0.923121602,DB0026410008629_,0.079994307,0.049787539,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,metoprolol,DB00264
,30771,DB00480,10008629,74,67354,69,67593,0.676444758,1.07623608,0.764596189,1.51656892,0.80384645,DB0048010008629_,0.21834701,0.073469843,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,lenalidomide,DB00480
,30772,DB01234,10008629,32,31593,37,32851,0.718340009,0.899310917,0.542186416,1.484134184,0.833618427,DB0123410008629_,0.181979503,-0.106126457,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,dexamethasone,DB01234
,30773,DB00099,10012174,43,2342,16,1939,0.005416352,2.224616427,1.223285913,4.244718547,0.021799357,DB0009910012174_,3.825874808,0.799584508,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,filgrastim,DB00099
,30775,DB00169,10037884,204,38487,77,18098,0.10880935,1.245787662,0.953424397,1.642083888,0.2242388,DB0016910037884_,1.495043723,0.21976799,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,30776,DB00480,10037884,456,66972,403,67259,0.064531691,1.136360824,0.991249554,1.303126395,0.151623804,DB0048010037884_,1.8863528,0.127830896,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,30777,DB00722,10037884,96,25307,113,25919,0.332205658,0.870105335,0.655478789,1.153060185,0.501063048,DB0072210037884_,0.691023342,-0.139141,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,30778,DB01234,10037884,170,31455,147,32741,0.10263381,1.203737664,0.959052891,1.512289351,0.214975361,DB0123410037884_,1.537231858,0.185431436,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,30779,DB01267,10017600,203,2649,30,3685,2.88001627525708e-45,9.409622225,6.367974077,14.35380769,1.38901335403912e-42,DB0126710017600_,96.37998023,2.241732807,female,10017600,Galactorrhoea,10038604,Reproductive system and breast disorders,Repro,paliperidone,DB01267
,30780,DB00341,10025482,361,11044,103,4965,3.43212734430492e-05,1.575621345,1.258996232,1.986015702,0.000319227,DB0034110025482_,8.049609029,0.454649699,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,30781,DB00741,10025482,151,3943,64,3110,2.55468734964476e-05,1.860762335,1.374563321,2.543225444,0.000246016,DB0074110025482_,8.310115625,0.620986261,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,30783,DB00341,10046306,125,11280,62,5006,0.474055517,0.894758385,0.653497334,1.235971963,0.63978996,DB0034110046306_,0.446615344,-0.111201558,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,cetirizine,DB00341
,30784,DB00741,10046306,44,4050,23,3151,0.137784725,1.488313982,0.877324371,2.588023991,0.266622851,DB0074110046306_,1.321920162,0.397643924,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,hydrocortisone,DB00741
,30786,DB00741,10047700,200,3894,111,3063,0.004129691,1.417218986,1.112549319,1.812835645,0.017534759,DB0074110047700_,4.043570129,0.34869649,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,hydrocortisone,DB00741
,30787,DB00341,10047899,211,11194,71,4997,0.043465724,1.326549836,1.007005555,1.765138094,0.112566782,DB0034110047899_,2.184208614,0.282581463,NA,10047899,Weight increased,10022891,Investigations,Inv,cetirizine,DB00341
,30788,DB00741,10047899,77,4017,43,3131,0.094489526,1.395672429,0.945857102,2.083217047,0.202476013,DB0074110047899_,1.597133852,0.333376327,NA,10047899,Weight increased,10022891,Investigations,Inv,hydrocortisone,DB00741
,30801,DB00864,10011906,153,6716,262,8130,0.000785541,0.70693676,0.573740069,0.868634543,0.004506318,DB0086410011906_,5.402274951,-0.346814065,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,30804,DB00331,10046735,228,24718,133,20619,0.000988554,1.429990826,1.148673268,1.786051732,0.005451983,DB0033110046735_,5.211775894,0.357668029,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,30805,DB09038,10046735,23,2225,30,2511,0.678676694,0.865239922,0.478432839,1.545659076,0.805455399,DB0903810046735_,0.216347448,-0.144748444,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,empagliflozin,DB09038
,30807,DB00588,10013710,72,16452,88,8380,5.0021673531181e-08,0.416761908,0.300554757,0.576280913,9.68389420088161e-07,DB0058810013710_,13.84763154,-0.875240184,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,30808,DB00709,10013710,15,625,53,586,1.40249644934318e-06,0.265605064,0.137476122,0.4846403,1.9402431142624e-05,DB0070910013710_,10.85011218,-1.325744794,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,lamivudine,DB00709
,30809,DB01048,10013710,20,445,74,1061,0.100804194,0.644559182,0.367762451,1.08352899,0.212075175,DB0104810013710_,1.550814467,-0.439188635,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,abacavir,DB01048
,30811,DB00563,10040829,95,46551,21,15327,0.10623391,1.489429064,0.92074999,2.517307509,0.220548007,DB0056310040829_,1.511639888,0.398392868,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,30812,DB00005,10041807,143,127939,41,42378,0.443591827,1.155283119,0.81116574,1.677755919,0.611694315,DB0000510041807_,0.491522607,0.144345439,NA,10041807,Sputum discoloured,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,30819,DB00983,10013952,64,3437,21,1719,0.104121505,1.524139346,0.914890348,2.63688029,0.217226269,DB0098310013952_,1.526815756,0.421429888,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,formoterol,DB00983
,30820,DB00222,10033645,39,3167,50,3078,0.201960998,0.758116009,0.484097672,1.179572049,0.351361474,DB0022210033645_,1.045939745,-0.276918859,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,glimepiride,DB00222
,30822,DB06655,10033645,462,3226,361,1758,2.66438527472847e-06,0.697484486,0.59904415,0.81241848,3.40960890682755e-05,DB0665510033645_,10.28632787,-0.360275007,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,liraglutide,DB06655
,30824,DB06218,10037844,42,1652,28,1408,0.33430145,1.27834965,0.769429096,2.153548279,0.503386436,DB0621810037844_,0.686397142,0.24556991,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,lacosamide,DB06218
,30829,DB00295,10010264,156,14507,90,9512,0.359171602,1.136544749,0.87005132,1.492047521,0.528957058,DB0029510010264_,0.636848026,0.127992738,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,30830,DB00451,10010264,904,46367,172,15247,5.76867839491543e-12,1.728186016,1.465106406,2.048484425,2.30090609423903e-10,DB0045110010264_,22.19254793,0.547072313,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,30831,DB00635,10010264,996,32057,465,23329,1.49275373425046e-15,1.558747345,1.393016941,1.746191349,9.82153489481185e-14,DB0063510010264_,29.95161389,0.443882515,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,30832,DB00863,10010264,235,10438,87,5753,0.001449688,1.488729432,1.156732625,1.930691631,0.007478176,DB0086310010264_,4.895766342,0.397923026,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,30833,DB00956,10010264,113,5701,37,3430,0.001152867,1.837355754,1.254021637,2.747435635,0.006196955,DB0095610010264_,5.083697252,0.608327448,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,30834,DB00956,10012735,279,5535,129,3338,0.013920843,1.304273987,1.049986048,1.627030784,0.046358717,DB0095610012735_,3.071345927,0.265646554,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,hydrocodone,DB00956
,30835,DB08932,10047700,1275,18168,211,6386,6.86915842283474e-27,2.123924176,1.829153505,2.475859816,1.21178408821618e-24,DB0893210047700_,55.06994851,0.753265404,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,30836,DB00295,10054236,43,14620,15,9587,0.032031857,1.879754139,1.023086792,3.644808949,0.089166786,DB0029510054236_,2.417246666,0.631140991,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,morphine,DB00295
,30837,DB00451,10054236,162,47109,42,15377,0.193337731,1.259009642,0.891381307,1.813610269,0.340837174,DB0045110054236_,1.076350412,0.230325414,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,30838,DB00635,10054236,155,32898,106,23688,0.70627331,1.052901157,0.816644627,1.361837972,0.824095261,DB0063510054236_,0.193469148,0.05154936,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,30839,DB00820,10054236,83,11832,24,5792,0.022768979,1.692877514,1.062565379,2.792086385,0.068343453,DB0082010054236_,2.683209505,0.526429752,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,tadalafil,DB00820
,30840,DB00863,10054236,50,10623,10,5830,0.00173876,2.74390021,1.373982122,6.074222186,0.008660029,DB0086310054236_,4.749037206,1.009380342,female,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,ranitidine,DB00863
,30842,DB08932,10054236,124,19319,19,6578,0.000667331,2.22223677,1.363253422,3.818653909,0.003939541,DB0893210054236_,5.536691065,0.798514243,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,30843,DB00005,10035528,125,127957,72,42347,0.000265789,0.57456361,0.426450387,0.779093824,0.001827907,DB0000510035528_,6.304583768,-0.554144466,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,etanercept,DB00005
,30852,DB00421,10000081,200,8703,85,5167,0.010975049,1.396917248,1.075847569,1.826686443,0.03834884,DB0042110000081_,3.261030991,0.334267843,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,30853,DB01257,10000081,31,905,21,547,0.771200215,0.892309867,0.490972085,1.65146891,0.874730199,DB0125710000081_,0.133839784,-0.113941822,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,eculizumab,DB01257
,30860,DB00028,10002855,73,13385,33,5582,0.748566427,0.922536572,0.602865639,1.438860314,0.857270327,DB0002810002855_,0.154001976,-0.080628259,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,human immunoglobulin g,DB00028
,30861,DB00421,10002855,136,8767,25,5227,1.79905715011373e-09,3.243169315,2.102482585,5.194650543,4.743050871689e-08,DB0042110002855_,16.86400017,1.176551035,female,10002855,Anxiety,10037175,Psychiatric disorders,Psych,spironolactone,DB00421
,30875,DB00028,10013968,419,13039,184,5431,0.555261149,0.948491265,0.793221153,1.137580473,0.708720679,DB0002810013968_,0.344293795,-0.052882699,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human immunoglobulin g,DB00028
,30877,DB01257,10016256,70,866,40,528,0.838223939,1.066938863,0.701804459,1.640590669,0.916840664,DB0125710016256_,0.086821579,0.064793672,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,eculizumab,DB01257
,30887,DB00028,10019211,1430,12028,405,5210,9.17533490786164e-14,1.529383008,1.36198102,1.72016053,4.73353637003225e-12,DB0002810019211_,26.07634855,0.424864392,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,30888,DB00421,10019211,692,8211,135,5117,2.0468828578128e-41,3.194157848,2.643315337,3.88315389,8.47280565631646e-39,DB0042110019211_,87.66395693,1.161323469,female,10019211,Headache,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,30889,DB01257,10019211,65,871,27,541,0.095994047,1.494919952,0.927394829,2.468718141,0.204780549,DB0125710019211_,1.585816367,0.402072662,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,eculizumab,DB01257
,30890,DB00028,10021097,84,13374,62,5553,0.000952407,0.562579931,0.399726314,0.795434509,0.005292047,DB0002810021097_,5.241550057,-0.575222056,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,human immunoglobulin g,DB00028
,30891,DB00421,10021097,329,8574,255,4997,0.001019048,0.751971276,0.634129676,0.892439816,0.005590687,DB0042110021097_,5.186653138,-0.285057152,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,spironolactone,DB00421
,30893,DB00028,10021789,217,13241,75,5540,0.174082644,1.210537167,0.925104056,1.598961131,0.316267784,DB0002810021789_,1.151166007,0.191064201,NA,10021789,Infection,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,30894,DB00421,10021789,113,8790,48,5204,0.058982148,1.393720977,0.984082674,2.000201793,0.141551771,DB0042110021789_,1.955089757,0.331977132,NA,10021789,Infection,10021881,Infections and infestations,Infec,spironolactone,DB00421
,30896,DB00028,10022437,59,13399,21,5594,0.623147659,1.172941585,0.701431542,2.034526513,0.763272034,DB0002810022437_,0.270140779,0.159514769,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,human immunoglobulin g,DB00028
,30897,DB00421,10022437,133,8770,66,5186,0.267885478,1.191654623,0.878685215,1.629378677,0.430266541,DB0042110022437_,0.8433504,0.175342781,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,spironolactone,DB00421
,30902,DB00028,10025482,325,13133,104,5511,0.01828209,1.311285833,1.045900812,1.655357004,0.057543377,DB0002810025482_,2.855216231,0.271008208,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,30903,DB00421,10025482,389,8514,103,5149,5.20968262663187e-15,2.283903237,1.828209879,2.874384544,3.19199318976733e-13,DB0042110025482_,28.77296066,0.825885925,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,30905,DB00028,10028735,38,13420,14,5601,0.762285492,1.132829058,0.599437468,2.265357581,0.868285351,DB0002810028735_,0.141234873,0.124718095,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human immunoglobulin g,DB00028
,30907,DB01257,10028813,45,891,14,554,0.027631863,1.997721055,1.064874655,3.9790299,0.079416492,DB0125710028813_,2.533049231,0.692007058,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,eculizumab,DB01257
,30908,DB00028,10029354,23,13435,31,5584,3.03561667156167e-05,0.308417489,0.171578346,0.546909439,0.000286864,DB0002810029354_,8.156502791,-1.176300929,male,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,human immunoglobulin g,DB00028
,30909,DB00421,10029354,46,8857,28,5224,0.904354846,0.968963421,0.592118714,1.611993738,0.957497529,DB0042110029354_,0.043432138,-0.031528417,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,spironolactone,DB00421
,30911,DB01257,10037660,31,905,35,533,0.0130188,0.52186463,0.307289784,0.882596785,0.043933644,DB0125710037660_,3.125074866,-0.650347054,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,eculizumab,DB01257
,30915,DB00028,10046571,341,13117,34,5581,4.43757430335161e-22,4.267435574,2.989908796,6.272321446,5.68983612505351e-20,DB0002810046571_,44.31302041,1.451013079,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,30917,DB00028,10047700,377,13081,113,5502,0.001536822,1.403296073,1.13147017,1.751467538,0.007849097,DB0002810047700_,4.847356825,0.338823808,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,human immunoglobulin g,DB00028
,30918,DB00421,10047700,383,8520,135,5117,6.76150987330765e-08,1.703825483,1.39226837,2.0953799,1.26992702407925e-06,DB0042110047700_,13.57655112,0.532876007,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,30920,DB00028,10047899,150,13308,36,5579,0.00205224,1.746711235,1.205420599,2.591667542,0.009931536,DB0002810047899_,4.61204009,0.557734726,NA,10047899,Weight increased,10022891,Investigations,Inv,human immunoglobulin g,DB00028
,30934,DB05676,10020751,209,46920,85,25244,0.03179078,1.322911179,1.022814853,1.723803401,0.088636504,DB0567610020751_,2.423211493,0.279834747,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,apremilast,DB05676
,30936,DB05676,10020772,131,46998,68,25261,0.881695311,1.035461526,0.766437765,1.409744267,0.950491592,DB0567610020772_,0.050775963,0.034847247,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,apremilast,DB05676
,30950,DB01261,10013700,93,3688,43,3260,0.000356061,1.911620858,1.313658855,2.820827008,0.002326677,DB0126110013700_,6.063314228,0.647951499,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,sitagliptin,DB01261
,30953,DB00273,10013496,55,8426,10,2183,0.357138264,1.424881956,0.717853698,3.140471704,0.526868808,DB0027310013496_,0.640803702,0.354088972,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,30956,DB00776,10016256,95,1810,40,1299,0.005470094,1.704217453,1.157338835,2.549619221,0.021976525,DB0077610016256_,3.817780428,0.533106034,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,oxcarbazepine,DB00776
,30957,DB00273,10016322,187,8294,22,2171,0.000131137,2.224718325,1.422296146,3.645470958,0.001004939,DB0027310016322_,6.902828622,0.799630312,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,30959,DB01255,10016322,114,2019,53,1525,0.003875563,1.624453735,1.154256019,2.310920619,0.016626272,DB0125510016322_,4.096771209,0.485171596,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,lisdexamfetamine,DB01255
,30960,DB00273,10024264,65,8416,15,2178,0.781937003,1.121423204,0.631065631,2.121620711,0.881222599,DB0027310024264_,0.126445019,0.114598596,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,30964,DB00273,10069327,45,8436,8,2185,0.395770831,1.456868151,0.678377363,3.583813979,0.565432997,DB0027310069327_,0.570163475,0.376289029,NA,10069327,Product quality issue,10077536,Product issues,Prod,topiramate,DB00273
,30970,DB00641,10039020,52,14072,159,12316,4.21246260350901e-17,0.286245768,0.204957563,0.39420661,3.26621178564113e-15,DB0064110039020_,33.35514556,-1.250904509,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,30973,DB01202,10069326,59,6655,48,5670,0.845955709,1.04724542,0.702068678,1.56896332,0.922538514,DB0120210069326_,0.080626154,0.046163308,NA,10069326,Product substitution issue,10077536,Product issues,Prod,levetiracetam,DB01202
,30974,DB01285,10013709,103,1173,47,562,0.855709926,1.049948033,0.725039428,1.538716069,0.930281057,DB0128510013709_,0.072268526,0.04874067,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,corticotropin,DB01285
,30975,DB01373,10013709,802,21918,234,7147,0.151738653,1.117581519,0.962468729,1.301592313,0.286372321,DB0137310013709_,1.250462492,0.111166992,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,30976,DB01285,10016173,50,1226,13,596,0.054091172,1.869195464,0.990865276,3.780795398,0.132654083,DB0128510016173_,2.020010418,0.625508105,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,corticotropin,DB01285
,30980,DB01373,10016454,290,22430,12,7369,2.11284935184942e-22,7.939301238,4.472015336,15.55326604,2.76299727429661e-20,DB0137310016454_,45.0353858,2.071825266,female,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,30981,DB00404,10048393,152,19740,24,9838,4.18955956075041e-09,3.156301573,2.04165887,5.081881699,1.02344398749372e-07,DB0040410048393_,16.09492225,1.149400954,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,30982,DB01050,10048393,167,17941,47,9324,0.000116717,1.846568291,1.32739975,2.612593337,0.000910762,DB0105010048393_,7.001228413,0.613328938,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,30983,DB01285,10048393,45,1231,8,601,0.006704015,2.745052172,1.270190116,6.785907468,0.025879723,DB0128510048393_,3.654295517,1.009800081,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,corticotropin,DB01285
,30984,DB01373,10048393,93,22627,18,7363,0.046004705,1.681185582,1.006700911,2.962555021,0.117493879,DB0137310048393_,2.141369041,0.519499248,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,calcium,DB01373
,30985,DB00563,10022004,199,46447,42,15306,0.007071357,1.561320719,1.114036659,2.234342971,0.026996457,DB0056310022004_,3.612049647,0.445532078,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,30996,DB00193,10037377,124,19196,63,8639,0.42883192,0.885806961,0.648197326,1.220831056,0.597354271,DB0019310037377_,0.515244923,-0.121256229,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,30997,DB00193,10038063,58,19262,28,8674,0.81550291,0.932802796,0.584038553,1.522360779,0.901086407,DB0019310038063_,0.104154125,-0.069561466,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,31000,DB00451,10046735,554,46717,90,15329,3.53939180971131e-11,2.019889582,1.612560355,2.554661853,1.24542053170364e-09,DB0045110046735_,20.50379259,0.703042848,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,31001,DB01156,10046735,143,13479,45,6283,0.022196579,1.481238453,1.051277625,2.122450915,0.067069441,DB0115610046735_,2.702026762,0.39287853,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,bupropion,DB01156
,31006,DB00715,10061818,41,4802,19,2268,1,1.019190128,0.576730153,1.863614351,1,DB0071510061818_,0,0.01900832,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,31011,DB00028,10012174,89,13369,32,5583,0.54828265,1.16145648,0.766481408,1.800675611,0.702748237,DB0002810012174_,0.352756578,0.149674804,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,human immunoglobulin g,DB00028
,31012,DB00073,10012174,47,7359,62,6345,0.033451743,0.653637419,0.43699088,0.972045556,0.09224497,DB0007310012174_,2.383307525,-0.425202486,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,rituximab,DB00073
,31013,DB00327,10012174,94,6044,70,4192,0.689236139,0.931386294,0.674455666,1.291293313,0.812584521,DB0032710012174_,0.207535344,-0.071081164,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,hydromorphone,DB00327
,31016,DB00425,10012174,171,12524,82,7402,0.131929859,1.232452939,0.940220652,1.62659758,0.258538459,DB0042510012174_,1.352710819,0.209006443,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,zolpidem,DB00425
,31017,DB00668,10012174,69,10022,19,4284,0.10158387,1.552327736,0.921920455,2.735784215,0.213277849,DB0066810012174_,1.54515951,0.439755569,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,epinephrine,DB00668
,31018,DB00804,10012174,56,2944,20,879,0.492686032,0.836025288,0.490760724,1.479402229,0.655556268,DB0080410012174_,0.422271139,-0.179096418,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,dicyclomine,DB00804
,31019,DB00813,10012174,142,10430,101,10067,0.02010262,1.356984779,1.042416633,1.771883555,0.062003915,DB0081310012174_,2.780557744,0.305265164,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,fentanyl,DB00813
,31020,DB01068,10012174,145,13618,62,6778,0.335666489,1.164009423,0.857542729,1.596044198,0.504834564,DB0106810012174_,0.6835245,0.151870445,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,clonazepam,DB01068
,31021,DB01075,10012174,222,19726,101,10996,0.102089549,1.225205061,0.962964119,1.567886764,0.214096711,DB0107510012174_,1.541327444,0.203108227,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,diphenhydramine,DB01075
,31022,DB01109,10012174,62,4350,31,4239,0.002349346,1.948810795,1.243965967,3.110392261,0.011087629,DB0110910012174_,4.501925303,0.667219338,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,heparin,DB01109
,31023,DB09140,10012174,85,3656,21,1777,0.004509039,1.96713632,1.204067405,3.351623609,0.018802945,DB0914010012174_,3.973741771,0.676578841,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,oxygen,DB09140
,31024,DB00395,10012735,92,2092,26,710,0.45054441,1.200832113,0.762540569,1.950770855,0.618232874,DB0039510012735_,0.480890074,0.183014744,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,carisoprodol,DB00395
,31025,DB00668,10012735,196,9895,74,4229,0.383743809,1.131985339,0.859872786,1.503546661,0.553743022,DB0066810012735_,0.59105456,0.123973029,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,epinephrine,DB00668
,31026,DB00804,10012735,255,2745,67,832,0.334181764,1.153531309,0.86765723,1.550483653,0.50329271,DB0080410012735_,0.68658335,0.142827941,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dicyclomine,DB00804
,31027,DB09140,10012735,403,3338,131,1667,2.82811811462372e-05,1.536212614,1.246824776,1.902244536,0.000269505,DB0914010012735_,8.218924209,0.429320046,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,oxygen,DB09140
,31028,DB00395,10028813,133,2051,26,710,0.008283081,1.770517685,1.144877162,2.834140288,0.030618635,DB0039510028813_,3.486146473,0.571271981,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,carisoprodol,DB00395
,31029,DB00668,10028813,458,9633,117,4186,1.71133588179271e-07,1.700994291,1.380801232,2.10910733,2.95548381425239e-06,DB0066810028813_,12.73184819,0.531212957,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,epinephrine,DB00668
,31030,DB09140,10028813,445,3296,110,1688,4.31577999595478e-12,2.071575161,1.663183831,2.59757859,1.75876398749878e-10,DB0914010028813_,22.46123965,0.728309265,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,oxygen,DB09140
,31031,DB00395,10047700,73,2111,19,717,0.331699024,1.30483804,0.772636277,2.306555375,0.500537233,DB0039510047700_,0.692073291,0.266078925,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,carisoprodol,DB00395
,31032,DB00668,10047700,251,9840,68,4235,0.000644309,1.588584961,1.207508435,2.113751076,0.00382381,DB0066810047700_,5.566507922,0.462843658,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,epinephrine,DB00668
,31033,DB00230,10013573,863,18811,301,8350,0.000348364,1.272627504,1.111995272,1.459677482,0.002285187,DB0023010013573_,6.081307636,0.241083664,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,31034,DB00697,10013573,238,5858,55,1751,0.10263448,1.293402787,0.955970019,1.776026641,0.214975361,DB0069710013573_,1.537231858,0.257276565,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,31036,DB00230,10016322,881,18793,285,8366,2.83763778704771e-06,1.376120683,1.199563542,1.582223164,3.60848133684321e-05,DB0023010016322_,10.22963846,0.319268441,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,31037,DB00697,10016322,132,5964,29,1777,0.154910135,1.356143066,0.898194925,2.11087198,0.290667301,DB0069710016322_,1.235575961,0.30464469,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,31038,DB00722,10016322,403,25000,275,25757,1.34486729546207e-07,1.509806925,1.290726564,1.768242985,2.37993718075226e-06,DB0072210016322_,12.94843647,0.411981779,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,31039,DB00697,10017577,158,5938,35,1771,0.118776744,1.346317592,0.924624778,2.009312505,0.239392556,DB0069710017577_,1.429650581,0.297373156,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,31040,DB00722,10017577,358,25045,244,25788,6.52739864599084e-07,1.510718791,1.279063909,1.78674689,9.80883565446275e-06,DB0072210017577_,11.53222698,0.412585558,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,31041,DB01060,10013968,282,8305,185,4896,0.283797326,0.898635773,0.74130926,1.091395847,0.448240157,DB0106010013968_,0.802426124,-0.106877474,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amoxicillin,DB01060
,31042,DB00688,10011906,141,6349,162,5216,0.004146056,0.715077381,0.564735543,0.904554684,0.01758544,DB0068810011906_,4.04068397,-0.335364518,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,31043,DB00471,10057362,48,14141,10,5455,0.078427622,1.851616874,0.924144988,4.107700429,0.175735905,DB0047110057362_,1.73877295,0.616059243,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,31044,DB00471,10069327,207,13982,66,5399,0.196145326,1.211051361,0.912071168,1.62596936,0.344409215,DB0047110069327_,1.065924751,0.191488876,NA,10069327,Product quality issue,10077536,Product issues,Prod,montelukast,DB00471
,31045,DB00503,10013710,55,658,163,850,1.45287581790242e-07,0.436097885,0.309870819,0.606356831,2.54932182066522e-06,DB0050310013710_,12.87968319,-0.829888554,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ritonavir,DB00503
,31047,DB08910,10017413,389,16355,344,17144,0.024976376,1.185359134,1.020994622,1.376664459,0.073418033,DB0891010017413_,2.611585691,0.170045795,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,pomalidomide,DB08910
,31048,DB08910,10047513,102,16642,77,17411,0.035549619,1.385866397,1.019987761,1.889519156,0.096586049,DB0891010047513_,2.337320964,0.326325501,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,pomalidomide,DB08910
,31051,DB06655,10016256,104,3584,59,2060,1,1.013163889,0.725569424,1.425995886,1,DB0665510016256_,0,0.013077998,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,liraglutide,DB06655
,31052,DB01257,10005630,35,901,24,544,0.681691165,0.880581941,0.502997841,1.565253458,0.807528608,DB0125710005630_,0.213776797,-0.127172294,NA,10005630,Blood lactate dehydrogenase increased,10022891,Investigations,Inv,eculizumab,DB01257
,31054,DB01257,10018884,50,886,28,540,0.810693581,1.08831281,0.662861221,1.818731274,0.898205372,DB0125710018884_,0.107356538,0.084628616,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,eculizumab,DB01257
,31058,DB00068,10016322,50,2184,9,656,0.209345424,1.668392318,0.806739197,3.880167119,0.360380148,DB0006810016322_,1.020595838,0.511860479,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,31059,DB01156,10016322,348,13274,102,6226,2.0093583218055e-05,1.600210017,1.277009608,2.019613969,0.000200499,DB0115610016322_,8.514702511,0.470134881,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,31062,DB00736,10000059,177,10414,65,5488,0.013935866,1.434984648,1.071940772,1.941153475,0.046394051,DB0073610000059_,3.070584047,0.361154151,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,31077,DB00555,10042033,52,6995,34,3452,0.206905338,0.754808404,0.479583631,1.201885907,0.35754831,DB0055510042033_,1.028484792,-0.281291331,NA,10042033,Stevens-Johnson syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,lamotrigine,DB00555
,31084,DB00264,10033645,103,29504,92,24800,0.718908281,0.941092696,0.703107001,1.261161956,0.833969776,DB0026410033645_,0.181558117,-0.060713637,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,31085,DB00641,10033645,59,14065,49,12426,0.772694754,1.063786845,0.715349501,1.58808216,0.875615308,DB0064110033645_,0.13282843,0.061835037,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,31087,DB00927,10038435,117,7380,93,4923,0.227379593,0.839237952,0.6321081,1.116836918,0.382619197,DB0092710038435_,0.960715049,-0.175260999,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,famotidine,DB00927
,31089,DB01307,10038435,27,2497,30,2039,0.284179963,0.734977961,0.418910462,1.28375231,0.44866933,DB0130710038435_,0.80146912,-0.307914765,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,insulin detemir,DB01307
,31090,DB06655,10038435,30,3658,22,2097,0.388054639,0.781773243,0.434825415,1.426303052,0.558047899,DB0665510038435_,0.583310479,-0.246190551,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,liraglutide,DB06655
,31100,DB00741,10020772,78,4016,52,3122,0.422640354,1.166054116,0.80783255,1.695090842,0.591592234,DB0074110020772_,0.524937676,0.153625499,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,hydrocortisone,DB00741
,31121,DB00497,10000060,125,19142,83,16292,0.081430462,1.281785833,0.962637365,1.714198418,0.180761734,DB0049710000060_,1.710575502,0.248254287,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,31122,DB00497,10003445,61,19206,57,16318,0.644020557,0.909256434,0.622797259,1.329169617,0.780257672,DB0049710003445_,0.248131065,-0.095128119,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,31125,DB00497,10048959,281,18986,198,16177,0.042323024,1.209213542,1.003287059,1.459598611,0.110341269,DB0049710048959_,2.20417727,0.189970183,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,31129,DB00331,10008531,146,24800,116,20636,0.755795243,1.047302851,0.814473762,1.349180977,0.863029583,DB0033110008531_,0.147306309,0.046218146,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,31133,DB00153,10012735,467,6956,194,3245,0.195640191,1.122976533,0.94274172,1.34156986,0.343812424,DB0015310012735_,1.06765905,0.115982779,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,31134,DB00190,10012735,99,3198,104,4570,0.036059573,1.360240786,1.018473026,1.815762026,0.097643545,DB0019010012735_,2.326431732,0.307661732,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,carbidopa,DB00190
,31135,DB06655,10012735,184,3504,109,2010,0.803467837,0.968311171,0.754893882,1.246863843,0.893667573,DB0665510012735_,0.112421415,-0.032201786,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,liraglutide,DB06655
,31136,DB06700,10012735,78,2147,18,600,0.530420867,1.210910593,0.71160613,2.166457156,0.687463942,DB0670010012735_,0.374745899,0.191372633,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,desvenlafaxine,DB06700
,31137,DB00153,10013946,73,7350,10,3429,4.37860126580934e-05,3.405226115,1.747545135,7.406209867,0.000394893,DB0015310013946_,7.836895982,1.225311344,female,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,31140,DB00331,10013946,153,24793,112,20640,0.32234997,1.137227937,0.884785923,1.465430738,0.490674598,DB0033110013946_,0.711974104,0.128593667,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,31143,DB06655,10013946,30,3658,24,2095,0.255794336,0.715963408,0.403445594,1.283332334,0.416538371,DB0665510013946_,0.875776695,-0.33412622,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,liraglutide,DB06655
,31155,DB00190,10028813,203,3094,160,4514,1.15978109785763e-08,1.850847673,1.489229279,2.303465333,2.57473362814085e-07,DB0019010028813_,15.17234957,0.615643736,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,carbidopa,DB00190
,31156,DB06655,10028813,353,3335,183,1936,0.2395349,1.119786232,0.925604398,1.35801529,0.397360356,DB0665510028813_,0.922911713,0.113137802,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,liraglutide,DB06655
,31161,DB00695,10033647,37,28012,35,20493,0.284457454,0.773395271,0.47367846,1.265006325,0.44895906,DB0069510033647_,0.800823576,-0.256965014,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,31164,DB00153,10037660,157,7266,83,3356,0.326480752,0.873690526,0.663172889,1.157895041,0.494998792,DB0015310037660_,0.703199957,-0.135029055,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,31165,DB00190,10037660,25,3272,49,4625,0.19401649,0.721206999,0.42589939,1.193349806,0.341725927,DB0019010037660_,1.073746247,-0.326829083,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,31166,DB00268,10037660,53,2922,26,1519,0.904876063,1.059683432,0.648000325,1.772996419,0.957667115,DB0026810037660_,0.043255041,0.057970215,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,31173,DB00047,10013911,40,9245,36,8482,1,1.019411058,0.632781918,1.647604416,1,DB0004710013911_,0,0.019225067,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,31175,DB00758,10013911,46,8254,43,10031,0.24042468,1.300050267,0.838085174,2.020192113,0.39833361,DB0075810013911_,0.92046541,0.26240293,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,31176,DB01076,10013911,126,25621,127,25456,0.949766287,0.985735369,0.763769124,1.272121066,0.988071196,DB0107610013911_,0.012000523,-0.014367349,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,31184,DB06228,10042316,50,15862,70,16006,0.082316035,0.720780371,0.490771302,1.051787837,0.182212048,DB0622810042316_,1.70258417,-0.327420806,NA,10042316,Subarachnoid haemorrhage,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,31188,DB00996,10048709,39,38914,20,22405,0.787011206,1.122741134,0.638941231,2.03224684,0.884476968,DB0099610048709_,0.122758806,0.115773136,NA,10048709,Urosepsis,10021881,Infections and infestations,Infec,gabapentin,DB00996
,31192,DB09038,10037844,69,2179,79,2462,1,0.986855507,0.70015861,1.388205076,1,DB0903810037844_,0,-0.013231646,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,empagliflozin,DB09038
,31204,DB00363,10033864,19,4609,34,6854,0.575936227,0.831050748,0.447207944,1.500977402,0.725353189,DB0036310033864_,0.321096585,-0.185064418,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,31206,DB06655,10012174,56,3632,50,2069,0.024802464,0.638099527,0.426180108,0.95764147,0.073053874,DB0665510012174_,2.616558108,-0.44926101,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,liraglutide,DB06655
,31207,DB06655,10047700,207,3481,111,2008,0.589824469,1.075735785,0.844278999,1.376425662,0.736574711,DB0665510047700_,0.305744607,0.073004879,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,liraglutide,DB06655
,31208,DB06655,10061428,47,3641,30,2089,0.635957836,0.89888399,0.554798556,1.476919519,0.773734718,DB0665510061428_,0.256526205,-0.106601296,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,liraglutide,DB06655
,31209,DB08910,10023424,51,16693,19,17469,5.98834321008863e-05,2.80895127,1.629225985,5.039429756,0.000514896,DB0891010023424_,7.571546292,1.0328112,female,10023424,Kidney infection,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,31213,DB00544,10013968,85,2350,93,2560,1,0.995653895,0.72904496,1.358363648,1,DB0054410013968_,0,-0.004355577,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluorouracil,DB00544
,31217,DB00497,10035598,108,19159,103,16272,0.406601517,0.890546174,0.672943276,1.17907265,0.57619327,DB0049710035598_,0.551312136,-0.115920326,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,31219,DB00996,10035598,134,38819,96,22329,0.11438192,0.802909872,0.612854527,1.055208326,0.232694459,DB0099610035598_,1.458029019,-0.21951281,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,31220,DB00422,10019211,197,3238,110,2839,0.000209147,1.570111333,1.230072728,2.012371977,0.001496105,DB0042210019211_,6.504890442,0.45114653,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,methylphenidate,DB00422
,31222,DB00422,10061422,40,3395,92,2857,4.46938705783799e-08,0.365938111,0.245053185,0.537903216,8.71820696217229e-07,DB0042210061422_,13.95268206,-1.005291055,male,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,methylphenidate,DB00422
,31223,DB00451,10007882,309,46962,102,15317,0.908573376,0.988064722,0.786855169,1.249307255,0.959033459,DB0045110007882_,0.041829315,-0.012007075,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,31225,DB00687,10035664,39,947,46,1039,0.824648484,0.930196832,0.585544867,1.47135784,0.907111606,DB0068710035664_,0.097489786,-0.072359068,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,fludrocortisone,DB00687
,31226,DB00169,10037423,129,38562,70,18105,0.323424082,0.865239652,0.641521254,1.1752843,0.491877959,DB0016910037423_,0.709524643,-0.144748756,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,31227,DB00451,10037423,187,47084,71,15348,0.277449527,0.858569193,0.649510363,1.145570893,0.441049944,DB0045110037423_,0.818597158,-0.152488005,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,31228,DB00480,10037423,180,67248,167,67495,0.484845641,1.081774457,0.871232142,1.343869218,0.648987507,DB0048010037423_,0.432341812,0.078602709,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,31230,DB00451,10038153,187,47084,92,15327,0.001658124,0.661669232,0.512446762,0.859397603,0.008339002,DB0045110038153_,4.786811694,-0.412989498,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,31233,DB00381,10002424,127,29233,165,22722,1.43892375840912e-05,0.59828046,0.470594672,0.759132833,0.000149613,DB0038110002424_,8.807460063,-0.513695639,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,31244,DB00203,10018830,33,13845,22,8916,0.89093936,0.965959646,0.546154629,1.74028907,0.954720579,DB0020310018830_,0.046336569,-0.034633219,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,31247,DB00722,10033647,57,25346,79,25953,0.086045763,0.738805058,0.515865759,1.052359915,0.188436816,DB0072210033647_,1.668992522,-0.302721185,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,31251,DB00451,10002424,73,47198,18,15401,0.330419014,1.32333366,0.781474837,2.356800472,0.499112912,DB0045110002424_,0.694922933,0.280154053,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,31253,DB00213,10005728,33,18862,23,13398,1,1.019151019,0.580347286,1.818593425,1,DB0021310005728_,0,0.018969946,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,pantoprazole,DB00213
,31255,DB00264,10005728,68,29539,64,24828,0.54088087,0.893050824,0.625087189,1.277189595,0.696334117,DB0026410005728_,0.36192568,-0.113111786,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,metoprolol,DB00264
,31257,DB00316,10005728,85,65389,51,36902,0.72170358,0.94057732,0.656870732,1.358698718,0.836020471,DB0031610005728_,0.179102179,-0.061261421,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,acetaminophen,DB00316
,31259,DB00480,10005728,102,67326,88,67574,0.31001258,1.163358135,0.865925613,1.565605255,0.47746642,DB0048010005728_,0.739261447,0.151310767,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,lenalidomide,DB00480
,31260,DB00695,10005728,59,27990,42,20486,0.920003368,1.028153115,0.68023362,1.566282648,0.964563326,DB0069510005728_,0.036079792,0.0277641,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,furosemide,DB00695
,31264,DB00996,10005728,49,38904,22,22403,0.388411159,1.28259472,0.760754617,2.228106689,0.55842403,DB0099610005728_,0.582636695,0.248885151,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,gabapentin,DB00996
,31265,DB01234,10005728,50,31575,43,32845,0.406562191,1.209554396,0.788213695,1.863108079,0.576153073,DB0123410005728_,0.551381902,0.190252024,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,dexamethasone,DB01234
,31267,DB00213,10023424,48,18847,11,13410,0.000282785,3.104676353,1.589232455,6.630865842,0.001924929,DB0021310023424_,6.252866183,1.132909476,female,10023424,Kidney infection,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,31269,DB00264,10023424,56,29551,28,24864,0.027807936,1.682765564,1.050647328,2.752277643,0.079800383,DB0026410023424_,2.528226972,0.520438609,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,31271,DB00316,10023424,144,65330,29,36924,2.88247939788508e-08,2.806437516,1.872728048,4.340509854,5.8416323032698e-07,DB0031610023424_,14.35308539,1.031915891,female,10023424,Kidney infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,31273,DB00480,10023424,112,67316,49,67613,5.07400710428869e-07,2.29591781,1.626849967,3.281480439,7.85917953660744e-06,DB0048010023424_,11.75382834,0.831132681,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,31274,DB00695,10023424,58,27991,16,20512,0.000229563,2.656344173,1.506008905,4.951869836,0.001617713,DB0069510023424_,6.42674177,0.976950806,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,31278,DB00996,10023424,69,38884,20,22405,0.005642016,1.987871021,1.193609959,3.453910149,0.022543193,DB0099610023424_,3.792322139,0.687064227,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,31279,DB01234,10023424,34,31591,21,32867,0.059909653,1.684417263,0.949658711,3.054956389,0.14330014,DB0123410023424_,1.942813969,0.521419666,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,31281,DB00213,10023547,58,18837,53,13368,0.209572402,0.776630957,0.525468866,1.149987616,0.360664589,DB0021310023547_,1.01980687,-0.25279,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,pantoprazole,DB00213
,31282,DB00215,10023547,42,11061,17,5259,0.675891093,1.174627858,0.653779666,2.203113518,0.803554995,DB0021510023547_,0.218709652,0.16095138,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,citalopram,DB00215
,31283,DB00264,10023547,114,29493,93,24799,0.834357341,1.030715294,0.776478824,1.371156186,0.914080763,DB0026410023547_,0.089836349,0.030253021,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,metoprolol,DB00264
,31285,DB00316,10023547,208,65266,166,36787,0.000979319,0.706285653,0.572917206,0.871741583,0.005411834,DB0031610023547_,5.21916716,-0.347735516,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,acetaminophen,DB00316
,31286,DB00404,10023547,44,19848,24,9838,0.700327004,0.908728816,0.540310911,1.563343156,0.819879108,DB0040410023547_,0.198598379,-0.095708562,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,alprazolam,DB00404
,31287,DB00695,10023547,107,27942,91,20437,0.312956227,0.860012378,0.643831438,1.150856546,0.480465769,DB0069510023547_,0.732999293,-0.150808497,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,furosemide,DB00695
,31288,DB00761,10023547,93,15214,43,8582,0.324516337,1.2199471,0.840350728,1.796261133,0.492987251,DB0076110023547_,0.707271965,0.198807497,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,potassium chloride,DB00761
,31289,DB00787,10023547,219,16781,222,17026,1,1.000889017,0.825599054,1.213316797,1,DB0078710023547_,0,0.000888622,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,acyclovir,DB00787
,31290,DB00813,10023547,29,10543,32,10136,0.610159803,0.871271826,0.508124445,1.488182013,0.752324346,DB0081310023547_,0.284587736,-0.137801266,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,fentanyl,DB00813
,31291,DB00996,10023547,148,38805,112,22313,0.032982069,0.759847425,0.590083577,0.98067235,0.091241202,DB0099610023547_,2.394248712,-0.274637623,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,gabapentin,DB00996
,31292,DB01234,10023547,330,31295,381,32507,0.163050139,0.899693044,0.773372666,1.046201501,0.3014647,DB0123410023547_,1.199102351,-0.105701636,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,dexamethasone,DB01234
,31295,DB00559,10003553,71,9588,9,3297,0.002760325,2.712729763,1.349258515,6.181444888,0.012627967,DB0055910003553_,4.371841289,0.997955421,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,31297,DB00682,10031252,36,19423,32,16332,0.903142876,0.945937358,0.57085763,1.574072961,0.957326661,DB0068210031252_,0.043610607,-0.05557893,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,warfarin,DB00682
,31299,DB01267,10056407,47,2805,74,3641,0.310566171,0.824454635,0.557522505,1.208725501,0.477968956,DB0126710056407_,0.738209495,-0.19303316,NA,10056407,Refusal of treatment by patient,10041244,Social circumstances,SocCi,paliperidone,DB01267
,31300,DB01164,10003549,69,6455,116,7820,0.037071622,0.720629466,0.525999728,0.981015691,0.0997316,DB0116410003549_,2.305272705,-0.32763019,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,31303,DB13961,10033645,30,9427,31,6383,0.116157916,0.655290442,0.382763676,1.120327475,0.235360248,DB1396110033645_,1.446637968,-0.422676719,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,31307,DB06228,10018276,89,15823,96,15980,0.659091237,0.936257622,0.69310027,1.263657346,0.791749239,DB0622810018276_,0.233510554,-0.065864603,NA,10018276,Gingival bleeding,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,31308,DB00758,10038428,29,8271,46,10028,0.29568138,0.764369344,0.462608315,1.24416012,0.461505601,DB0075810038428_,0.773261089,-0.268704172,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,clopidogrel,DB00758
,31311,DB00126,10035664,381,9790,287,5658,0.00103956,0.767255909,0.65416473,0.900588144,0.005691487,DB0012610035664_,5.168783665,-0.264934883,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,31312,DB00421,10035664,459,8444,176,5076,3.44321382095217e-07,1.567689569,1.309988097,1.882620941,5.53039262350919e-06,DB0042110035664_,12.10525175,0.449602924,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,spironolactone,DB00421
,31313,DB00537,10035664,201,7356,177,4121,2.07835946148524e-05,0.636181534,0.515297626,0.786011685,0.0002065,DB0053710035664_,8.485208252,-0.452271325,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,31314,DB01225,10035664,205,4839,196,4444,0.720897304,0.96053136,0.782444418,1.179489778,0.835410838,DB0122510035664_,0.179831654,-0.040268648,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,enoxaparin,DB01225
,31318,DB00005,10055798,124,127958,49,42370,0.291787376,0.837920669,0.597299958,1.191833366,0.457206032,DB0000510055798_,0.782621154,-0.17683185,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,etanercept,DB00005
,31320,DB01098,10033645,31,8118,42,7167,0.077751642,0.651653841,0.39556812,1.062842616,0.174548569,DB0109810033645_,1.745552245,-0.428241776,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,31321,DB00404,10033645,38,19854,28,9834,0.116744779,0.672206444,0.401577074,1.137975786,0.236239773,DB0040410033645_,1.442908004,-0.397189778,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,31324,DB00091,10071066,45,5465,25,2645,0.609160462,0.871202806,0.521648572,1.485936729,0.751674676,DB0009110071066_,0.28545166,-0.137880486,NA,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,cyclosporine,DB00091
,31327,DB01255,10053762,107,2026,79,1499,1,1.002117482,0.736289121,1.368643852,1,DB0125510053762_,0,0.002115243,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lisdexamfetamine,DB01255
,31329,DB00363,10012218,11,4617,44,6844,0.002139364,0.370619117,0.172431592,0.730221174,0.010279382,DB0036310012218_,4.577615123,-0.992580382,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,31331,DB01076,10018627,46,25701,79,25504,0.003014302,0.577825049,0.392542679,0.841872096,0.01356578,DB0107610018627_,4.300204858,-0.54848414,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,31333,DB06403,10017955,151,21320,43,6618,0.672124426,1.090050378,0.771259182,1.56932419,0.800970013,DB0640310017955_,0.22193177,0.086223913,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,31334,DB06403,10046571,226,21245,25,6636,3.49165178602277e-08,2.823725831,1.8620197,4.460544856,6.95551854457056e-07,DB0640310046571_,14.17856027,1.03805723,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,31336,DB01097,10003988,106,6159,23,1480,0.736468839,1.107449373,0.697536918,1.828883914,0.847817883,DB0109710003988_,0.165089427,0.102059509,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,31341,DB01097,10020772,109,6156,12,1491,0.007213655,2.199786253,1.205386241,4.400125146,0.027420235,DB0109710020772_,3.59647404,0.788360198,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,leflunomide,DB01097
,31346,DB01097,10033425,183,6082,38,1465,0.43808367,1.159979593,0.80997139,1.699603096,0.606476097,DB0109710033425_,0.500089962,0.148402412,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,31350,DB00421,10002034,225,8678,126,5126,0.654812078,1.0548031,0.841944282,1.326232119,0.788516377,DB0042110002034_,0.237602103,0.053354115,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,spironolactone,DB00421
,31354,DB00421,10008479,273,8630,100,5152,2.16743377296707e-05,1.629721447,1.287864431,2.075839264,0.000213935,DB0042110008479_,8.449836463,0.488409109,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,31360,DB00421,10020772,121,8782,46,5206,0.009845029,1.559284283,1.09972551,2.244067229,0.035126455,DB0042110020772_,3.348800734,0.444226923,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,spironolactone,DB00421
,31362,DB00421,10028334,157,8746,66,5186,0.020945396,1.410485486,1.049213843,1.914074167,0.06410313,DB0042110028334_,2.747262089,0.343933962,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,spironolactone,DB00421
,31370,DB00421,10060933,50,8853,22,5230,0.272655982,1.342609898,0.797145749,2.331118292,0.43556354,DB0042110060933_,0.831114592,0.294615405,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,31374,DB00983,10022000,46,3455,14,1726,0.128565226,1.641289205,0.88360118,3.242126586,0.253589747,DB0098310022000_,1.372037487,0.495482034,NA,10022000,Influenza,10021881,Infections and infestations,Infec,formoterol,DB00983
,31375,DB00983,10063829,52,3449,36,1704,0.137464549,0.713661414,0.455764464,1.128517759,0.266169848,DB0098310063829_,1.323620649,-0.337346639,NA,10063829,Device malfunction,10077536,Product issues,Prod,formoterol,DB00983
,31377,DB00863,10013781,60,10613,17,5823,0.016292853,1.936400452,1.113740632,3.543427478,0.052579207,DB0086310013781_,2.945434535,0.660830812,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,31393,DB00186,10049119,51,16850,13,9995,0.004287962,2.327002979,1.246673529,4.666060394,0.01807539,DB0018610049119_,4.013203943,0.844581164,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,31397,DB00373,10013709,91,1741,60,1227,0.735042831,1.068888531,0.756494303,1.519363218,0.846837642,DB0037310013709_,0.166246289,0.066619353,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,timolol,DB00373
,31405,DB00158,10043521,47,16768,10,8094,0.015570605,2.268650708,1.130586564,5.038511023,0.050765735,DB0015810043521_,2.980533663,0.819185253,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,31406,DB00264,10043521,67,29540,22,24870,6.46889108545009e-05,2.563872715,1.563036517,4.361616068,0.000548942,DB0026410043521_,7.507517665,0.941518895,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,31407,DB00451,10043521,153,47118,18,15401,4.58222022822543e-06,2.778396497,1.699461833,4.815203048,5.48218746922646e-05,DB0045110043521_,9.81142127,1.021873962,female,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,31409,DB00678,10043521,50,15549,20,10704,0.038731285,1.720973592,1.005562926,3.053930893,0.103104298,DB0067810043521_,2.272014204,0.542890173,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,31410,DB00863,10043521,40,10633,16,5824,0.328515083,1.369297064,0.749110673,2.621593952,0.497108256,DB0086310043521_,0.698947458,0.314297516,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,31411,DB00999,10043521,59,21371,19,12220,0.033168389,1.775569565,1.043010443,3.155577621,0.09165592,DB0099910043521_,2.389713715,0.574121253,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,31412,DB00454,10011906,20,1947,35,566,1.44532202778174e-10,0.166267482,0.090169834,0.298768023,4.59097154081486e-09,DB0045410011906_,19.19917417,-1.794157452,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,meperidine,DB00454
,31413,DB01109,10011906,208,4204,165,4105,0.056566261,1.230888362,0.993853246,1.526359371,0.137061595,DB0110910011906_,1.987324859,0.207736154,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,31415,DB01073,10053762,65,1000,107,1543,0.747027893,0.937348795,0.670714243,1.301827482,0.856011865,DB0107310053762_,0.155471042,-0.06469982,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,fludarabine,DB01073
,31416,DB01109,10053762,165,4247,127,4143,0.049508631,1.267360205,0.995340073,1.616745935,0.1240747,DB0110910053762_,2.086871476,0.236936159,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,heparin,DB01109
,31426,DB01104,10071404,23,15440,36,7250,7.60142839423621e-06,0.300014017,0.169612332,0.520763626,8.53314308530851e-05,DB0110410071404_,9.368967697,-1.203926081,male,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,31429,DB00321,10000087,83,7364,25,2825,0.330945261,1.273581063,0.804051771,2.084039894,0.499649407,DB0032110000087_,0.693848612,0.241832667,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,amitriptyline,DB00321
,31430,DB00331,10000087,354,24592,189,20563,5.61908605361521e-07,1.56613353,1.307624984,1.880498863,8.61210944135719e-06,DB0033110000087_,11.66234127,0.448609862,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,31431,DB00758,10000087,112,8188,84,9990,0.000861699,1.626704702,1.21301416,2.188528247,0.004873535,DB0075810000087_,5.323935722,0.486556314,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,31432,DB01104,10000087,178,15285,55,7231,0.005787754,1.531026537,1.124080875,2.114005882,0.023003118,DB0110410000087_,3.772125517,0.42593845,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,31434,DB00331,10001551,69,24877,53,20699,0.715982136,1.083265002,0.74595189,1.580808589,0.831970578,DB0033110001551_,0.183958202,0.07997963,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,metformin,DB00331
,31435,DB00381,10001551,59,29301,89,22798,8.45295200108201e-05,0.515808991,0.364542348,0.72519807,0.000691521,DB0038110001551_,7.276616381,-0.662018754,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,amlodipine,DB00381
,31437,DB01104,10001551,52,15411,33,7253,0.199841259,0.74159767,0.469959644,1.18550436,0.348811804,DB0110410001551_,1.053222745,-0.298948406,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,sertraline,DB01104
,31439,DB00331,10003481,70,24876,55,20697,0.787675114,1.058930845,0.732850902,1.536735273,0.884977148,DB0033110003481_,0.122193456,0.057259762,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,metformin,DB00331
,31440,DB00381,10003481,69,29291,83,22804,0.008608085,0.647229476,0.463138743,0.902030661,0.031590018,DB0038110003481_,3.454914101,-0.435054371,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,amlodipine,DB00381
,31441,DB00758,10003481,25,8275,30,10044,1,1.011481327,0.569937747,1.780650938,1,DB0075810003481_,0,0.011415917,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,clopidogrel,DB00758
,31442,DB01104,10003481,59,15404,29,7257,0.908911517,0.958473543,0.604047516,1.552152402,0.95913476,DB0110410003481_,0.041723693,-0.042413319,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,sertraline,DB01104
,31443,DB00381,10022523,194,29166,281,22606,1.62932248539476e-11,0.535124765,0.442945236,0.645392678,5.98975405994423e-10,DB0038110022523_,21.23580058,-0.625255354,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,31444,DB00722,10022523,63,25340,131,25901,2.37961643450618e-06,0.491571992,0.357835031,0.669156315,3.08043427633563e-05,DB0072210022523_,10.38785488,-0.710146877,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,31446,DB00005,10012601,336,127746,136,42283,0.05475899,0.817730925,0.667869613,1.005845523,0.133932046,DB0000510012601_,2.010422731,-0.201221938,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,etanercept,DB00005
,31448,DB00005,10040047,223,127859,83,42336,0.354876454,0.889608282,0.688317233,1.159198078,0.524674613,DB0000510040047_,0.644976994,-0.116974045,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,etanercept,DB00005
,31454,DB00437,10008190,65,6856,98,11448,0.516971069,1.107497412,0.795494638,1.533170458,0.676622364,DB0043710008190_,0.390641969,0.102102886,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,31460,DB00437,10019196,21,6900,38,11508,0.892968776,0.921688325,0.513467984,1.61242194,0.955415161,DB0043710019196_,0.045609309,-0.081548155,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,allopurinol,DB00437
,31466,DB00390,10042772,72,4073,60,3241,0.791675053,0.954854715,0.666219251,1.372841336,0.887231487,DB0039010042772_,0.119649354,-0.046196081,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,digoxin,DB00390
,31467,DB00437,10042772,40,6881,120,11426,0.000978056,0.553521724,0.376451968,0.798836131,0.005408839,DB0043710042772_,5.219720729,-0.591454279,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,31474,DB00783,10016173,259,16455,6,367,0.831678727,0.962745071,0.432202464,2.66500467,0.912067678,DB0078310016173_,0.092041083,-0.037966626,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,estradiol,DB00783
,31491,DB00294,10016256,162,14209,6,162,0.013389399,0.307881222,0.13552389,0.863825944,0.044926132,DB0029410016256_,3.102735646,-1.178041213,male,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,etonogestrel,DB00294
,31498,DB00433,10029366,91,7565,59,5961,0.282303125,1.215327182,0.864669088,1.719460263,0.446367357,DB0043310029366_,0.806612995,0.195013326,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,prochlorperazine,DB00433
,31499,DB00904,10029366,170,22899,95,14361,0.376155715,1.122280004,0.867209025,1.459573275,0.545940365,DB0090410029366_,0.605245531,0.115362334,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,ondansetron,DB00904
,31500,DB01225,10029366,38,5006,22,4618,0.091867653,1.593315663,0.917072173,2.832807844,0.198222071,DB0122510029366_,1.618367307,0.465817168,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,enoxaparin,DB01225
,31511,DB00334,10047942,30,2819,29,2783,1,1.021271417,0.590584189,1.76861535,1,DB0033410047942_,0,0.021048338,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,olanzapine,DB00334
,31512,DB00370,10047942,48,4493,33,3630,0.502171205,1.175137978,0.737163415,1.894125781,0.66349503,DB0037010047942_,0.410233916,0.161385568,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,mirtazapine,DB00370
,31513,DB00433,10047942,220,7436,131,5889,0.01045522,1.329976971,1.063424868,1.668671693,0.036870458,DB0043310047942_,3.300344647,0.285161627,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,prochlorperazine,DB00433
,31514,DB01225,10047942,74,4970,43,4597,0.015467168,1.591692462,1.07611951,2.380237683,0.050487019,DB0122510047942_,2.98603903,0.464797892,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,enoxaparin,DB01225
,31518,DB00005,10007695,51,128031,17,42402,1,0.993556201,0.56424177,1.83532932,1,DB0000510007695_,0,-0.00646465,NA,10007695,Carpal tunnel decompression,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,31519,DB00005,10030995,48,128034,10,42409,0.22374118,1.589861441,0.794173739,3.525117283,0.378189571,DB0000510030995_,0.9723597,0.463646869,NA,10030995,Oral mucosal blistering,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,31522,DB00332,10013709,81,2603,55,1601,0.591145595,0.905837501,0.631433632,1.307755824,0.737581561,DB0033210013709_,0.304378605,-0.098895348,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ipratropium,DB00332
,31523,DB00706,10013709,29,1046,624,15301,0.048470274,0.679866797,0.449120002,0.992387484,0.122204322,DB0070610013709_,2.102060866,-0.385858387,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,31524,DB00332,10013968,283,2401,151,1505,0.131238242,1.17470791,0.95039027,1.456265153,0.257549275,DB0033210013968_,1.356544217,0.161019529,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipratropium,DB00332
,31525,DB01222,10013968,892,8382,473,4932,0.082206915,1.109648444,0.985872174,1.250004982,0.182014427,DB0122210013968_,1.703669324,0.104043248,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,31526,DB00331,10069327,154,24792,119,20633,0.583331536,1.077044104,0.841731123,1.380878844,0.731425341,DB0033110069327_,0.312760127,0.074220349,NA,10069327,Product quality issue,10077536,Product issues,Prod,metformin,DB00331
,31528,DB00338,10069327,153,33521,83,22189,0.161592182,1.22018249,0.92756843,1.614722238,0.299585616,DB0033810069327_,1.205355038,0.199000429,NA,10069327,Product quality issue,10077536,Product issues,Prod,omeprazole,DB00338
,31529,DB00404,10069327,110,19782,38,9824,0.054286026,1.437547698,0.985047853,2.139048877,0.133014048,DB0040410069327_,2.017300536,0.362938674,NA,10069327,Product quality issue,10077536,Product issues,Prod,alprazolam,DB00404
,31530,DB00451,10069327,360,46911,71,15348,5.05068723285688e-05,1.658829697,1.282080058,2.172570251,0.000445794,DB0045110069327_,7.715654645,0.506112352,NA,10069327,Product quality issue,10077536,Product issues,Prod,levothyroxine,DB00451
,31532,DB01222,10069327,133,9141,85,5320,0.524505165,0.910655796,0.686934805,1.212692649,0.682641031,DB0122210069327_,0.381786134,-0.093590284,NA,10069327,Product quality issue,10077536,Product issues,Prod,budesonide,DB01222
,31535,DB00060,10021789,54,9454,16,2449,0.656296787,0.874259442,0.491902092,1.639609864,0.789851928,DB0006010021789_,0.235909784,-0.134378103,NA,10021789,Infection,10021881,Infections and infestations,Infec,interferon beta-1a,DB00060
,31536,DB00060,10035664,201,9307,55,2410,0.696634873,0.94632391,0.696519213,1.304093955,0.817493979,DB0006010035664_,0.201511742,-0.055170369,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,interferon beta-1a,DB00060
,31546,DB00043,10005750,47,6366,13,2287,0.464460263,1.298780882,0.68974901,2.621703796,0.631531842,DB0004310005750_,0.459606915,0.261426042,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,omalizumab,DB00043
,31547,DB00169,10005750,403,38288,151,18024,0.017232201,1.256328199,1.038629926,1.526336123,0.054972803,DB0016910005750_,2.900916703,0.228193339,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,31548,DB00186,10005750,155,16746,75,9933,0.150987342,1.225807785,0.923550389,1.639279496,0.28526494,DB0018610005750_,1.254336915,0.203600043,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,lorazepam,DB00186
,31549,DB00404,10005750,165,19727,69,9793,0.26455395,1.187081273,0.890079975,1.597777488,0.426508868,DB0040410005750_,0.85212212,0.171497583,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,alprazolam,DB00404
,31550,DB00588,10005750,149,16375,67,8401,0.387208981,1.140920062,0.848524143,1.547746496,0.557267673,DB0058810005750_,0.584709593,0.131835009,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,31552,DB08868,10005750,154,9048,31,2480,0.125116056,1.36158347,0.918303929,2.078369842,0.248793398,DB0886810005750_,1.391132453,0.308648339,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,fingolimod,DB08868
,31553,DB08868,10013968,256,8946,64,2447,0.580588864,1.094111665,0.825698973,1.467853403,0.72902968,DB0886810013968_,0.316040834,0.089942769,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fingolimod,DB08868
,31554,DB00043,10016256,279,6134,82,2218,0.112779905,1.230250236,0.953583971,1.601350928,0.230246199,DB0004310016256_,1.468606112,0.207217593,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,31555,DB00043,10019211,285,6128,77,2223,0.024143856,1.342608985,1.035179272,1.758627764,0.071571136,DB0004310019211_,2.63706341,0.294614725,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,omalizumab,DB00043
,31556,DB00186,10019211,760,16141,241,9767,2.47409271591228e-19,1.908168587,1.644808316,2.219820849,2.422030802151e-17,DB0018610019211_,38.25934022,0.646143927,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,31557,DB08868,10019211,802,8400,165,2346,0.000431116,1.35743851,1.139174965,1.625055669,0.002728604,DB0886810019211_,5.903965215,0.305599475,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,31559,DB00169,10019301,85,38606,54,18121,0.084016084,0.738825005,0.518992342,1.059808512,0.185086767,DB0016910019301_,1.686930551,-0.302694185,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,31561,DB00404,10019301,36,19856,15,9847,0.656255774,1.190184529,0.635235605,2.341021366,0.789820652,DB0040410019301_,0.235949383,0.174108361,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,alprazolam,DB00404
,31563,DB00588,10019301,33,16491,19,8449,0.66311523,0.889862361,0.491030501,1.65735615,0.794619732,DB0058810019301_,0.229891603,-0.116688479,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,31565,DB08868,10019301,204,8998,74,2437,0.038108644,0.746654767,0.567284607,0.991676659,0.101818023,DB0886810019301_,2.284568149,-0.292152361,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,fingolimod,DB08868
,31574,DB00186,10033557,155,16746,33,9975,5.14820896008071e-09,2.797714196,1.909636032,4.210962034,1.23242871143644e-07,DB0018610033557_,15.90910887,1.028802725,female,10033557,Palpitations,10007541,Cardiac disorders,Card,lorazepam,DB00186
,31575,DB00404,10033557,190,19702,34,9828,1.30382292839569e-09,2.787512183,1.925595814,4.146421595,3.5398789655864e-08,DB0040410033557_,17.15658821,1.025149507,female,10033557,Palpitations,10007541,Cardiac disorders,Card,alprazolam,DB00404
,31576,DB00472,10033557,62,10697,11,4301,0.009083003,2.266142321,1.181638606,4.778086335,0.032971514,DB0047210033557_,3.412111297,0.818078968,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,fluoxetine,DB00472
,31577,DB00588,10033557,157,16367,36,8432,3.75439171295084e-06,2.246706549,1.554088265,3.327065295,4.59316668256517e-05,DB0058810033557_,9.98835577,0.809465388,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,fluticasone propionate,DB00588
,31578,DB08868,10033557,128,9074,12,2499,6.79085482035528e-05,2.937492729,1.621173385,5.843418143,0.000571924,DB0886810033557_,7.466503666,1.077556404,female,10033557,Palpitations,10007541,Cardiac disorders,Card,fingolimod,DB08868
,31595,DB01216,10013709,16,220,346,6769,0.169804907,1.422714164,0.789983764,2.396693835,0.310675668,DB0121610013709_,1.16900578,0.35256643,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,finasteride,DB01216
,31599,DB00338,10036018,80,33594,73,22199,0.047390768,0.724185817,0.520423877,1.009024959,0.120197455,DB0033810036018_,2.118619427,-0.322707266,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,31602,DB00338,10040808,32,33642,43,22229,0.00289964,0.491720194,0.301062435,0.795688928,0.013140535,DB0033810040808_,4.332053578,-0.709845436,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,omeprazole,DB00338
,31614,DB00338,10060820,73,33601,21,22251,0.000445156,2.301934336,1.400232908,3.940043424,0.002804632,DB0033810060820_,5.876483023,0.833749785,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,31616,DB00338,10061225,70,33604,34,22238,0.16020322,1.362452368,0.891833437,2.117973212,0.297761395,DB0033810061225_,1.211462801,0.309286288,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,31621,DB00115,10005557,96,18329,84,10388,0.003970416,0.647757404,0.477738269,0.879619433,0.016979158,DB0011510005557_,4.075768689,-0.434239029,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,31623,DB00343,10005557,49,8687,34,5061,0.427077804,0.839640114,0.530409286,1.343133508,0.595703791,DB0034310005557_,0.518011731,-0.174781915,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,diltiazem,DB00343
,31624,DB00758,10005557,60,8240,94,9980,0.123100953,0.773095659,0.548882311,1.081641073,0.245834847,DB0075810005557_,1.403095321,-0.257352487,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,clopidogrel,DB00758
,31625,DB00927,10005557,47,7450,32,4984,1,0.982579635,0.612913596,1.59363079,1,DB0092710005557_,0,-0.017573885,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,famotidine,DB00927
,31634,DB00722,10005654,39,25364,28,26004,0.178347074,1.427985515,0.856211612,2.410282861,0.32178683,DB0072210005654_,1.133865972,0.35626472,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,lisinopril,DB00722
,31637,DB01076,10005654,45,25702,25,25558,0.02241954,1.789884584,1.074032308,3.047061582,0.067556583,DB0107610005654_,2.694789767,0.582151139,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,31657,DB00115,10009033,118,18307,62,10410,0.64146297,1.082246421,0.788427902,1.498035945,0.778171378,DB0011510009033_,0.250808498,0.0790389,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,31658,DB00126,10009033,55,10116,44,5901,0.11850512,0.729202635,0.480935719,1.111289791,0.238946539,DB0012610009033_,1.431515439,-0.315803622,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,31660,DB00343,10009033,131,8605,61,5034,0.152547443,1.256332507,0.918336378,1.735157471,0.287537436,DB0034310009033_,1.246402216,0.228196768,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,31661,DB00722,10009033,169,25234,125,25907,0.005897697,1.388043107,1.094214354,1.764648444,0.023351806,DB0072210009033_,3.757080943,0.327894918,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,31662,DB00758,10009033,82,8218,63,10011,0.007144634,1.585505764,1.126268251,2.241288006,0.027233801,DB0075810009033_,3.60329638,0.46090345,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,31663,DB01076,10009033,195,25552,173,25410,0.295417471,1.12090063,0.907997784,1.384713855,0.461307554,DB0107610009033_,0.773690313,0.114132496,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,31665,DB01222,10009033,273,9001,176,5229,0.29684537,0.901118827,0.740499997,1.098855701,0.462683897,DB0122210009033_,0.770711185,-0.104118147,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,31671,DB00722,10016454,55,25348,31,26001,0.006931789,1.819866023,1.150859996,2.925385433,0.026594961,DB0072210016454_,3.627033505,0.598762885,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,31674,DB01076,10016454,54,25693,26,25557,0.002315945,2.065890447,1.27096084,3.437851744,0.010961486,DB0107610016454_,4.513367412,0.725561343,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,31679,DB00115,10021519,56,18369,25,10447,0.355169222,1.273969258,0.781384959,2.132082633,0.524959822,DB0011510021519_,0.644433548,0.242137426,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,31680,DB00126,10021519,35,10136,21,5924,1,0.974071473,0.550893236,1.762727798,1,DB0012610021519_,0,-0.026270597,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,31686,DB01076,10021519,33,25714,33,25550,1,0.993621957,0.594185132,1.661509913,1,DB0107610021519_,0,-0.00639847,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,31706,DB00115,10037400,55,18370,19,10453,0.068709646,1.647152263,0.961771103,2.940752235,0.15900647,DB0011510037400_,1.838810388,0.499047896,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,31707,DB00126,10037400,38,10133,20,5925,0.78575393,1.110982585,0.629731015,2.017200063,0.883734037,DB0012610037400_,0.123599125,0.105244835,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,31709,DB00341,10037400,41,11364,11,5057,0.174571504,1.658597156,0.836403162,3.581036823,0.316893093,DB0034110037400_,1.14919081,0.505972159,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,31710,DB00343,10037400,85,8651,21,5074,0.000166374,2.373884037,1.456630365,4.036158914,0.001233784,DB0034310037400_,6.697669426,0.864527448,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,31711,DB00722,10037400,66,25337,36,25996,0.002035126,1.880981988,1.234360804,2.90815121,0.009862331,DB0072210037400_,4.619032752,0.631793975,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,31713,DB00927,10037400,43,7454,17,4999,0.065328861,1.69627139,0.946263063,3.176209728,0.152994591,DB0092710037400_,1.877352709,0.528432542,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,31714,DB01076,10037400,97,25650,88,25495,0.556195623,1.095592524,0.812030405,1.479923866,0.709603298,DB0107610037400_,0.343049201,0.091295335,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,31716,DB01222,10037400,60,9214,38,5367,0.675855184,0.919716859,0.601674232,1.421436157,0.803554995,DB0122210037400_,0.218709652,-0.083689418,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,31719,DB00115,10040943,50,18375,15,10457,0.027897531,1.896921867,1.04747732,3.639033591,0.080000721,DB0011510040943_,2.525719627,0.640232502,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,31724,DB00722,10040943,61,25342,48,25984,0.180054476,1.303017032,0.8777535,1.944139653,0.32389418,DB0072210040943_,1.127338421,0.264682369,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,31727,DB01076,10040943,47,25700,44,25539,0.834011789,1.061513902,0.688256287,1.639847902,0.913778366,DB0107610040943_,0.090167225,0.059696099,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,31789,DB01248,10000081,81,2619,35,1339,0.427703854,1.183141293,0.781909897,1.823107846,0.596276489,DB0124810000081_,0.517050812,0.168173014,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,docetaxel,DB01248
,31791,DB01259,10012735,292,977,6,68,0.001447355,3.385215425,1.456482814,9.642283845,0.007466877,DB0125910012735_,4.897278453,1.219417545,female,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lapatinib,DB01259
,31792,DB00126,10003285,62,10109,14,5931,0.000731093,2.598120886,1.436825913,5.029860664,0.004242116,DB0012610003285_,5.462693075,0.954788447,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,31793,DB00169,10003285,207,38484,58,18117,0.000344892,1.680137391,1.249434141,2.289969308,0.002267791,DB0016910003285_,6.088949044,0.51887557,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,31794,DB00316,10003285,282,65192,110,36843,0.000879853,1.448823681,1.157863659,1.823539395,0.004959134,DB0031610003285_,5.30652407,0.370751973,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,31796,DB00635,10003285,175,32878,50,23744,6.67034695701203e-10,2.527582622,1.835540615,3.535867231,1.91408373105962e-08,DB0063510003285_,17.77144171,0.927263361,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,31799,DB06724,10003285,54,7875,15,3904,0.053388118,1.784607461,0.991040101,3.409530139,0.13135645,DB0672410003285_,2.029840661,0.579198481,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,31800,DB08895,10003285,250,27864,52,6594,0.41983858,1.137733119,0.839910516,1.566948599,0.588738747,DB0889510003285_,0.529772746,0.129037791,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,31806,DB14513,10003285,39,7138,15,3549,0.469737256,1.292732083,0.695606552,2.527993745,0.636052121,DB1451310003285_,0.452474767,0.256757873,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,31807,DB00126,10042674,92,10079,32,5913,0.011342908,1.686611215,1.115338512,2.610650507,0.03935432,DB0012610042674_,3.235149535,0.522721318,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,31808,DB00158,10042674,149,16666,37,8067,0.00015019,1.949193395,1.350649937,2.877880502,0.001127926,DB0015810042674_,6.78737467,0.667415643,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,31809,DB00169,10042674,300,38391,58,18117,1.22276151470683e-11,2.440868128,1.836334778,3.293863795,4.61123191019641e-10,DB0016910042674_,21.49735588,0.892353766,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,31810,DB00472,10042674,49,10710,12,4300,0.154772788,1.639418476,0.858321649,3.390082947,0.290471796,DB0047210042674_,1.236248794,0.494341591,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,31811,DB00563,10042674,419,46227,79,15269,1.88294058169497e-06,1.751773577,1.37359913,2.258963047,2.51106510349327e-05,DB0056310042674_,10.59221846,0.560628748,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,31812,DB01592,10042674,63,6213,21,3046,0.130747138,1.470730519,0.88328242,2.542975064,0.256804672,DB0159210042674_,1.359439513,0.385759229,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,31813,DB06724,10042674,51,7878,10,3909,0.005820739,2.530411723,1.268513938,5.596304474,0.023108298,DB0672410042674_,3.767563512,0.928382026,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,31814,DB08895,10042674,434,27680,96,6550,0.578171141,1.069810858,0.854263662,1.351048294,0.726966202,DB0889510042674_,0.318875292,0.067481864,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,31820,DB14513,10042674,56,7121,17,3547,0.080576451,1.640744789,0.93785994,3.016784008,0.179350666,DB1451310042674_,1.718412359,0.495150278,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,31821,DB00158,10052904,204,16611,49,8055,3.8377562310091e-06,2.018798991,1.469856543,2.820250098,4.68425458704779e-05,DB0015810052904_,9.968718668,0.702502776,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,31822,DB00316,10052904,382,65092,149,36804,9.49551869885553e-05,1.449582468,1.195971396,1.764406993,0.000762339,DB0031610052904_,7.179119538,0.371275562,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,31824,DB00635,10052904,313,32740,117,23677,3.41721663402367e-10,1.93463536,1.558496582,2.415142842,1.03006352322606e-08,DB0063510052904_,18.39106027,0.659918864,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,31826,DB01592,10052904,47,6229,11,3056,0.02446,2.096092939,1.069600236,4.488092286,0.072318601,DB0159210052904_,2.626673907,0.740075107,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,iron,DB01592
,31827,DB06724,10052904,65,7864,15,3904,0.005809857,2.151117944,1.211495626,4.066922118,0.023072451,DB0672410052904_,3.769115971,0.765987681,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,31828,DB08895,10052904,1225,26889,314,6332,0.195955629,0.918687114,0.808375729,1.046456439,0.344237564,DB0889510052904_,1.066423266,-0.084809678,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,31834,DB14513,10052904,54,7123,21,3543,0.389739419,1.279057398,0.758406662,2.23333667,0.559629654,DB1451310052904_,0.580480046,0.246123399,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,31851,DB00316,10011703,44,65430,23,36930,0.800632267,1.079766952,0.637905904,1.87354781,0.892233477,DB0031610011703_,0.114027435,0.076745233,NA,10011703,Cyanosis,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,31863,DB00316,10018100,73,65401,73,36880,0.000711634,0.563938452,0.401924034,0.791178178,0.004148894,DB0031610018100_,5.484913448,-0.572810162,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,31865,DB00451,10018100,32,47239,24,15395,0.002791309,0.434530875,0.247937452,0.771222731,0.0127433,DB0045110018100_,4.362749607,-0.833488278,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,31887,DB00338,10022116,105,33569,32,22240,7.20580642867543e-05,2.173843611,1.450513736,3.340058544,0.000601571,DB0033810022116_,7.41596603,0.77649685,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,31890,DB00758,10022116,41,8259,45,10029,0.664934909,1.10636594,0.705836922,1.72977737,0.796056299,DB0075810022116_,0.228085368,0.101080716,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,31909,DB00047,10045555,34,9251,23,8495,0.289001717,1.357429629,0.775911706,2.415565774,0.454127045,DB0004710045555_,0.789378286,0.305592933,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,31911,DB00316,10045555,203,65271,152,36801,0.009195528,0.753017012,0.606964509,0.935763265,0.033294916,DB0031610045555_,3.402350564,-0.283667459,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,31913,DB00451,10045555,115,47156,47,15372,0.200835106,0.797614678,0.563123528,1.145695345,0.349970218,DB0045110045555_,1.049907219,-0.226129657,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,31914,DB00758,10045555,25,8275,36,10038,0.522975,0.842404997,0.484295697,1.443978232,0.681358011,DB0075810045555_,0.383667398,-0.171494386,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,31932,DB00316,10058046,58,65416,39,36914,0.399038073,0.839219564,0.549620446,1.293817853,0.568910354,DB0031610058046_,0.564032407,-0.175282909,NA,10058046,Post procedural complication,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,31935,DB00451,10058046,46,47225,12,15407,0.545266295,1.250600573,0.651750421,2.594319023,0.700076911,DB0045110058046_,0.356565077,0.223623894,NA,10058046,Post procedural complication,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,31943,DB00047,10069327,64,9221,49,8469,0.346635137,1.199590925,0.812966648,1.779628289,0.516060411,DB0004710069327_,0.661531445,0.181980603,NA,10069327,Product quality issue,10077536,Product issues,Prod,insulin glargine,DB00047
,31944,DB00126,10069327,45,10126,12,5933,0.012934325,2.197092714,1.141899499,4.566624815,0.043699068,DB0012610069327_,3.130428514,0.787134993,NA,10069327,Product quality issue,10077536,Product issues,Prod,ascorbic acid,DB00126
,31945,DB00316,10069327,184,65290,88,36865,0.206667972,1.180572955,0.910584856,1.540450238,0.357280255,DB0031610069327_,1.029234778,0.165999876,NA,10069327,Product quality issue,10077536,Product issues,Prod,acetaminophen,DB00316
,31946,DB00343,10069327,33,8703,20,5075,0.887384076,0.962198852,0.535365216,1.771404658,0.953324525,DB0034310069327_,0.047799903,-0.038534143,NA,10069327,Product quality issue,10077536,Product issues,Prod,diltiazem,DB00343
,31948,DB00758,10069327,50,8250,37,10037,0.023172747,1.643994823,1.052310377,2.589530903,0.0692981,DB0075810069327_,2.669337783,0.497129147,NA,10069327,Product quality issue,10077536,Product issues,Prod,clopidogrel,DB00758
,31953,DB00186,10022052,40,16861,11,9997,0.020300883,2.155966091,1.085039151,4.661588266,0.062542044,DB0018610022052_,2.771916245,0.768238925,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,31956,DB00567,10012378,85,4434,18,2063,0.001781579,2.196879175,1.305831097,3.893704308,0.008843301,DB0056710012378_,4.72809503,0.787037796,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,cephalexin,DB00567
,31958,DB00316,10029216,192,65282,47,36906,3.57519978123051e-08,2.309421011,1.670569507,3.249725594,7.10310856006379e-07,DB0031610029216_,14.15756314,0.836996849,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,31961,DB00567,10033371,184,4335,57,2024,0.007181954,1.507090618,1.10837459,2.075724981,0.027331353,DB0056710033371_,3.599720789,0.410181049,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,31963,DB00567,10051055,30,4489,32,2049,0.001343485,0.427977618,0.250474574,0.729450933,0.007019877,DB0056710051055_,4.959009541,-0.848684379,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,cephalexin,DB00567
,31969,DB00575,10043071,37,5207,29,3800,0.803143859,0.9311151,0.556115316,1.572842473,0.893441443,DB0057510043071_,0.112674484,-0.071372379,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,clonidine,DB00575
,31974,DB08895,10013538,140,27974,26,6620,0.277673787,1.274249257,0.833256975,2.020271452,0.441299606,DB0889510013538_,0.818031255,0.242357187,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,31987,DB00126,10037087,269,9902,103,5842,0.000169829,1.540786733,1.220283013,1.957659498,0.001256038,DB0012610037087_,6.679793225,0.432293151,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ascorbic acid,DB00126
,31989,DB00165,10037087,45,2100,20,1346,0.199649524,1.441998815,0.829922199,2.589939541,0.348655465,DB0016510037087_,1.053671049,0.366030217,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,pyridoxine,DB00165
,31990,DB00169,10037087,927,37764,267,17908,1.38589442577448e-13,1.64639497,1.433537034,1.895807133,6.95859311967186e-12,DB0016910037087_,25.6910438,0.498588031,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,31991,DB01409,10037087,120,5911,50,3916,0.005589303,1.589913173,1.131016822,2.263808983,0.022364869,DB0140910037087_,3.800263894,0.463679407,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,tiotropium,DB01409
,31992,DB11133,10037087,76,2355,26,1548,0.003858674,1.921117961,1.209998608,3.140190372,0.016563788,DB1113310037087_,4.10053641,0.652907288,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,omega-3 fatty acids,DB11133
,31994,DB00165,10037844,74,2071,37,1329,0.236258535,1.283348883,0.848037012,1.971576059,0.393455445,DB0016510037844_,0.932787446,0.249472976,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,pyridoxine,DB00165
,31995,DB00169,10037844,1122,37569,449,17726,0.003623547,1.17901853,1.054258454,1.320283195,0.015755987,DB0016910037844_,4.150534841,0.164682338,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,31996,DB01409,10037844,129,5902,81,3885,0.775794435,1.048326902,0.785422928,1.406072568,0.877822795,DB0140910037844_,0.130310533,0.047195467,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,tiotropium,DB01409
,31997,DB11133,10037844,75,2356,46,1528,0.850169766,1.057422497,0.71851538,1.570585558,0.925866436,DB1113310037844_,0.077025292,0.05583434,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,omega-3 fatty acids,DB11133
,31998,DB00126,10047513,97,10074,38,5907,0.039019428,1.496727704,1.017191421,2.242581113,0.103698061,DB0012610047513_,2.266271863,0.403281194,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ascorbic acid,DB00126
,32001,DB00169,10047513,361,38330,117,18058,0.000379688,1.453617058,1.175929475,1.807743377,0.002455843,DB0016910047513_,6.009285094,0.374054973,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,32012,DB00186,10001760,208,16693,35,9973,4.47995677641702e-15,3.550334157,2.470235483,5.24009512,2.76097687850226e-13,DB0018610001760_,28.91802165,1.267041728,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,32014,DB00788,10001760,130,9226,11,5050,4.53217464771077e-14,6.468956286,3.493485954,13.28899946,2.41639372444376e-12,DB0078810001760_,26.74874488,1.86701478,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,naproxen,DB00788
,32015,DB00811,10001760,90,2708,23,4133,7.89972369286493e-18,5.970708658,3.731956942,9.919488921,6.6552640149665e-16,DB0081110001760_,34.94595337,1.786865624,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,ribavirin,DB00811
,32016,DB01104,10001760,156,15307,16,7270,2.64817171338408e-12,4.63097716,2.760804315,8.308112669,1.11193599818371e-10,DB0110410001760_,22.91974829,1.532767895,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,sertraline,DB01104
,32018,DB00186,10003285,49,16852,17,9991,0.056309576,1.708820117,0.966406374,3.166858056,0.136654095,DB0018610003285_,1.9903024,0.535803142,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,32020,DB00788,10003285,54,9302,13,5048,0.00668442,2.254093825,1.212570309,4.506865246,0.025823042,DB0078810003285_,3.656488101,0.812748041,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,32022,DB01104,10003285,55,15408,18,7268,0.208952736,1.441304303,0.83272464,2.610155938,0.359998865,DB0110410003285_,1.021654401,0.36554847,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,32031,DB00811,10011224,49,2749,62,4094,0.435246556,1.176969104,0.789672886,1.745817068,0.603657715,DB0081110011224_,0.504747939,0.162942578,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ribavirin,DB00811
,32033,DB00186,10013781,105,16796,34,9974,0.001958943,1.833852715,1.234005791,2.787799286,0.009575194,DB0018610013781_,4.64857953,0.606419062,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,32035,DB00788,10013781,41,9315,14,5047,0.157037891,1.586694492,0.846348209,3.154617196,0.293538683,DB0078810013781_,1.225745849,0.461652916,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,32036,DB00811,10013781,28,2770,31,4125,0.286542624,1.344975714,0.775457104,2.323334543,0.451328671,DB0081110013781_,0.795559444,0.296375956,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,ribavirin,DB00811
,32037,DB01104,10013781,92,15371,22,7264,0.003323307,1.97618447,1.229346852,3.308501299,0.014693543,DB0110410013781_,4.220347101,0.68116795,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,32038,DB00186,10013911,96,16805,37,9971,0.02462237,1.539440795,1.042428975,2.316670065,0.072678157,DB0018610013911_,2.621714389,0.43141923,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,32040,DB00788,10013911,46,9310,37,5024,0.083027782,0.67088969,0.425108498,1.065302211,0.183478519,DB0078810013911_,1.69565768,-0.399150553,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,32041,DB01104,10013911,50,15413,22,7264,0.899436051,1.071110461,0.636210059,1.858959228,0.956490275,DB0110410013911_,0.044484657,0.068695924,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,32042,DB00211,10019211,113,1323,47,1584,5.30712760716499e-10,2.877610417,2.013306684,4.168386217,1.55316591492915e-08,DB0021110019211_,17.98038537,1.056960233,female,10019211,Headache,10029205,Nervous system disorders,Nerv,midodrine,DB00211
,32050,DB00186,10021789,138,16763,81,9927,1,1.008928204,0.760460387,1.345991802,1,DB0018610021789_,0,0.008888584,NA,10021789,Infection,10021881,Infections and infestations,Infec,lorazepam,DB00186
,32052,DB00788,10021789,82,9274,42,5019,0.850215347,1.056609673,0.71861946,1.573947463,0.925877715,DB0078810021789_,0.07701311,0.05506536,NA,10021789,Infection,10021881,Infections and infestations,Infec,naproxen,DB00788
,32054,DB01104,10021789,137,15326,56,7230,0.394650977,1.154079922,0.838706639,1.606572003,0.564554189,DB0110410021789_,0.571718906,0.143303422,NA,10021789,Infection,10021881,Infections and infestations,Infec,sertraline,DB01104
,32055,DB00186,10022004,91,16810,27,9981,0.001097057,2.001120515,1.289015326,3.201643906,0.00594131,DB0018610022004_,5.125825571,0.693707281,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,32057,DB00788,10022004,64,9292,27,5034,0.321555666,1.284172038,0.805987688,2.097698027,0.489848486,DB0078810022004_,0.713659149,0.250114183,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,32058,DB01104,10022004,96,15367,22,7264,0.001450352,2.062639452,1.286158059,3.446916768,0.00748087,DB0110410022004_,4.895406178,0.72398645,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,32072,DB00788,10037087,166,9190,64,4997,0.021366195,1.410301955,1.048571063,1.916476931,0.065148245,DB0078810037087_,2.731089919,0.343803834,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,naproxen,DB00788
,32074,DB01104,10037844,357,15106,121,7165,0.001271736,1.399416156,1.133273272,1.737840083,0.006702942,DB0110410037844_,5.005208742,0.336055118,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sertraline,DB01104
,32088,DB00186,10044034,52,16849,20,9988,0.112336003,1.541242672,0.903880879,2.727172941,0.229589599,DB0018610044034_,1.471461916,0.432589021,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,32093,DB00186,10047571,90,16811,33,9975,0.019057487,1.618230696,1.074036431,2.492305783,0.059490644,DB0018610047571_,2.821936216,0.48133339,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,lorazepam,DB00186
,32095,DB00788,10047571,59,9297,17,5044,0.021510401,1.882860097,1.081359961,3.449332152,0.0654816,DB0078810047571_,2.725986087,0.632791949,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,naproxen,DB00788
,32097,DB01104,10047571,122,15341,29,7257,0.000591095,1.990003308,1.317033205,3.098635219,0.003551703,DB0110410047571_,5.640328133,0.688136301,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,sertraline,DB01104
,32099,DB00211,10047700,75,1361,35,1596,5.69838867877688e-06,2.512133123,1.648578438,3.893160577,6.62795776564546e-05,DB0021110047700_,9.621628738,0.921132242,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,midodrine,DB00211
,32100,DB00211,10047895,26,1410,32,1599,0.791755226,0.921404804,0.524635221,1.604590087,0.887266787,DB0021110047895_,0.119609567,-0.081855812,NA,10047895,Weight decreased,10022891,Investigations,Inv,midodrine,DB00211
,32113,DB08910,10007554,17,16727,39,17449,0.006930693,0.454747254,0.241107467,0.823246496,0.026594639,DB0891010007554_,3.627045635,-0.788013501,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,pomalidomide,DB08910
,32114,DB00333,10003239,38,3033,27,3125,0.169769675,1.450004249,0.859945611,2.476155524,0.310654455,DB0033310003239_,1.169074062,0.371566487,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,methadone,DB00333
,32115,DB00620,10003239,141,4687,59,3073,0.004144713,1.566790934,1.144099552,2.168544146,0.017582921,DB0062010003239_,4.040827247,0.449029536,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,triamcinolone,DB00620
,32117,DB00620,10005557,47,4781,29,3103,0.906279756,1.051871057,0.646874622,1.737110781,0.958151532,DB0062010005557_,0.042749339,0.050570538,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,triamcinolone,DB00620
,32120,DB00333,10013573,44,3027,42,3110,0.745883906,1.076302487,0.686797614,1.688884538,0.854980527,DB0033310013573_,0.156676586,0.073531544,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,methadone,DB00333
,32121,DB00620,10013573,150,4678,76,3056,0.083985134,1.289309376,0.968098751,1.728930273,0.185049604,DB0062010013573_,1.687131359,0.254106708,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,triamcinolone,DB00620
,32122,DB00620,10013968,198,4630,110,3022,0.190960988,1.174805865,0.921521513,1.504027554,0.337768553,DB0062010013968_,1.085394373,0.161102913,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,triamcinolone,DB00620
,32124,DB00620,10021789,38,4790,21,3111,0.594846094,1.175185086,0.670966814,2.112164674,0.74054655,DB0062010021789_,0.300366784,0.161425655,NA,10021789,Infection,10021881,Infections and infestations,Infec,triamcinolone,DB00620
,32129,DB00620,10037153,191,4637,128,3004,0.770256266,0.966670626,0.7649815,1.224873668,0.874164144,DB0062010037153_,0.134487113,-0.033897456,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,triamcinolone,DB00620
,32138,DB00005,10044055,181,127901,54,42365,0.546037699,1.110241478,0.814963494,1.534256561,0.700725054,DB0000510044055_,0.355639689,0.104577539,NA,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,32141,DB00005,10048762,273,127809,98,42321,0.508405947,0.922417071,0.729504661,1.174422843,0.668958542,DB0000510048762_,0.402033191,-0.080757803,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,32153,DB00761,10010774,350,14957,174,8451,0.182194053,1.13654976,0.942972503,1.373868474,0.326646934,DB0076110010774_,1.118875405,0.127997147,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,32154,DB01377,10010774,91,3705,48,2622,0.116763035,1.341606426,0.932060927,1.952232268,0.236253041,DB0137710010774_,1.442851841,0.293867721,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,magnesium oxide,DB01377
,32160,DB01377,10029331,51,3745,52,2618,0.068889076,0.685676787,0.455133441,1.032515928,0.159322721,DB0137710029331_,1.836823442,-0.377348918,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,magnesium oxide,DB01377
,32162,DB00761,10031009,51,15256,13,8612,0.008687956,2.214506948,1.186313734,4.441078622,0.031823151,DB0076110031009_,3.447561226,0.795029782,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,32173,DB00016,10046571,63,2699,25,2265,0.001150479,2.114441327,1.306233148,3.520321778,0.006187283,DB0001610046571_,5.08525918,0.74879063,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,erythropoietin,DB00016
,32174,DB00341,10046571,265,11140,55,5013,2.87730411256729e-08,2.168095256,1.612964422,2.959896829,5.83339287302979e-07,DB0034110046571_,14.35449685,0.77384902,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,cetirizine,DB00341
,32175,DB00537,10046571,314,7243,111,4187,7.24508482644136e-06,1.635212026,1.308229317,2.056139086,8.18204316489844e-05,DB0053710046571_,9.41098357,0.491772475,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,32176,DB11093,10046571,45,1612,8,652,0.030442955,2.274461819,1.053548531,5.617869667,0.085641683,DB1109310046571_,2.457583159,0.821743461,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,calcium citrate,DB11093
,32190,DB00295,10009802,13,14650,39,9563,2.49426191639122e-07,0.217602003,0.106507758,0.416689221,4.14291781815755e-06,DB0029510009802_,12.39411023,-1.52508756,male,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,morphine,DB00295
,32191,DB00295,10027599,86,14577,13,9589,1.08799705804239e-08,4.351498291,2.413164683,8.509091397,2.42870511003349e-07,DB0029510027599_,15.23073741,1.470520221,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,morphine,DB00295
,32192,DB00273,10043607,36,8445,14,2179,0.217454185,0.663515649,0.34849343,1.334212672,0.370433133,DB0027310043607_,0.993082327,-0.41020284,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,topiramate,DB00273
,32193,DB00295,10043607,83,14580,81,9521,0.01275521,0.669171572,0.486139411,0.921365381,0.043230055,DB0029510043607_,3.141219305,-0.401714792,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,morphine,DB00295
,32194,DB00273,10046571,124,8357,15,2178,0.002955837,2.154275127,1.253684719,3.973803529,0.013338054,DB0027310046571_,4.317134143,0.767454299,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,topiramate,DB00273
,32199,DB00273,10053762,405,8076,125,2068,0.077705501,0.829665794,0.67309684,1.028252756,0.174475365,DB0027310053762_,1.745971722,-0.186732317,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,topiramate,DB00273
,32200,DB00295,10053762,272,14391,202,9400,0.184092966,0.879544942,0.729027183,1.062481319,0.329041453,DB0029510053762_,1.11157154,-0.128350617,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,32204,DB00710,10003549,54,2352,6,195,0.460962609,0.746270883,0.31587639,2.149864199,0.628264871,DB0071010003549_,0.464793432,-0.292666631,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ibandronate,DB00710
,32206,DB00710,10003988,142,2264,9,192,0.528498492,1.337910362,0.670674667,3.034038744,0.685868611,DB0071010003988_,0.377069198,0.291108965,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ibandronate,DB00710
,32209,DB00710,10013709,69,2337,7,194,0.659618998,0.818334045,0.369664244,2.140318587,0.792073157,DB0071010013709_,0.233101521,-0.200484657,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ibandronate,DB00710
,32216,DB00331,10019196,64,24882,41,20711,0.202893295,1.299298408,0.864000584,1.973552065,0.352435254,DB0033110019196_,1.042888349,0.261824433,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,32220,DB00331,10021114,50,24896,19,20733,0.003382957,2.1914547,1.268906584,3.937478871,0.014904631,DB0033110021114_,4.206083298,0.78456557,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,metformin,DB00331
,32222,DB00331,10021519,40,24906,24,20728,0.211720313,1.387069919,0.815716194,2.40645476,0.363480516,DB0033110021519_,1.012029585,0.32719355,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,32224,DB00331,10022437,419,24527,266,20486,0.000495495,1.315654684,1.124259681,1.541821834,0.003068822,DB0033110022437_,5.786461494,0.2743344,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,metformin,DB00331
,32230,DB00331,10031161,86,24860,32,20720,5.79070467537162e-05,2.239854179,1.476162135,3.475977432,0.000500522,DB0033110031161_,7.59985945,0.806410765,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,32235,DB00331,10033425,610,24336,297,20455,5.22847859244127e-15,1.726304239,1.498355416,1.992379039,3.19737171731864e-13,DB0033110033425_,28.77127707,0.545982845,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,32237,DB00331,10038423,30,24916,28,20724,0.693443788,0.891168859,0.514311521,1.548532864,0.815403848,DB0033110038423_,0.204071769,-0.115221354,NA,10038423,Renal cyst,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,32248,DB00331,10050296,33,24913,25,20727,0.792429225,1.098241374,0.633234234,1.927079943,0.887531177,DB0033110050296_,0.119311629,0.09371015,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,32264,DB00335,10035598,41,8425,39,5426,0.085486754,0.677101526,0.425347634,1.079296966,0.18751726,DB0033510035598_,1.673884382,-0.389934053,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atenolol,DB00335
,32269,DB00215,10021789,82,11021,29,5247,0.185684437,1.346204692,0.870555337,2.135861834,0.331041845,DB0021510021789_,1.105510492,0.297289294,NA,10021789,Infection,10021881,Infections and infestations,Infec,citalopram,DB00215
,32270,DB00273,10021789,47,8434,14,2179,0.634084909,0.867335079,0.468382626,1.709206189,0.772439256,DB0027310021789_,0.258201906,-0.142329896,NA,10021789,Infection,10021881,Infections and infestations,Infec,topiramate,DB00273
,32271,DB01156,10021789,79,13543,28,6300,0.251855338,1.312418045,0.842194628,2.100692276,0.411910373,DB0115610021789_,0.886949495,0.271871272,NA,10021789,Infection,10021881,Infections and infestations,Infec,bupropion,DB01156
,32272,DB00215,10022116,50,11053,10,5266,0.008369363,2.382053465,1.192731748,5.272797469,0.030864779,DB0021510022116_,3.478139594,0.867962916,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,32274,DB01156,10022116,58,13564,11,6317,0.004067538,2.455513267,1.27503132,5.191990697,0.017321223,DB0115610022116_,4.055822794,0.89833581,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,32275,DB00215,10022437,196,10907,83,5193,0.40115387,1.124309197,0.863503027,1.474733892,0.570982264,DB0021510022437_,0.560397131,0.1171688,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,32284,DB00215,10047899,178,10925,57,5219,0.00912035,1.491767521,1.099049461,2.051140954,0.033079676,DB0021510047899_,3.4088362,0.399961673,NA,10047899,Weight increased,10022891,Investigations,Inv,citalopram,DB00215
,32285,DB00273,10047899,169,8312,33,2160,0.158996308,1.330784953,0.909081825,2.001934724,0.296167384,DB0027310047899_,1.216830497,0.285768958,NA,10047899,Weight increased,10022891,Investigations,Inv,topiramate,DB00273
,32289,DB01156,10049119,57,13565,13,6315,0.019835624,2.041134612,1.102954836,4.067813045,0.061353188,DB0115610049119_,2.79110815,0.713505836,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,32315,DB14500,10013709,279,7530,121,3952,0.086533287,1.210100479,0.97063942,1.51597118,0.18925219,DB1450010013709_,1.664674816,0.190703397,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,32320,DB00115,10000059,277,18148,108,10364,0.000751402,1.464701518,1.166984699,1.849336067,0.004338885,DB0011510000059_,5.440137811,0.381651479,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,32321,DB00190,10000059,43,3254,32,4642,0.006378142,1.916722809,1.18211785,3.137189128,0.02486274,DB0019010000059_,3.694384994,0.650616857,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,carbidopa,DB00190
,32322,DB00678,10000059,238,15361,122,10602,0.008067842,1.346419491,1.076368564,1.691308744,0.029992678,DB0067810000059_,3.50680201,0.29744884,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,32323,DB01268,10000059,77,2066,94,3036,0.236238858,1.203693967,0.874065172,1.653500666,0.393455445,DB0126810000059_,0.932787446,0.185395134,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,32324,DB11089,10000059,127,10048,66,8341,0.002185929,1.597300338,1.175465785,2.187729086,0.010463211,DB1108910000059_,4.559889916,0.468314916,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,32326,DB00190,10010774,71,3226,148,4526,0.006580387,0.673082116,0.498004448,0.902620822,0.025493607,DB0019010010774_,3.669327577,-0.395887942,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,carbidopa,DB00190
,32327,DB01268,10010774,82,2061,145,2985,0.16731182,0.8190841,0.613284931,1.087945782,0.307279987,DB0126810010774_,1.179995936,-0.199568514,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,32330,DB00115,10013786,127,18298,43,10429,0.002954569,1.683320657,1.181481153,2.439683825,0.013333476,DB0011510013786_,4.317477377,0.520768424,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,32332,DB00678,10013786,103,15496,51,10673,0.058371357,1.391004021,0.984165307,1.987742883,0.140444975,DB0067810013786_,1.962939506,0.330025804,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,32333,DB11089,10013786,49,10126,43,8364,0.833837762,0.941274475,0.611432435,1.453722922,0.913682907,DB1108910013786_,0.090271697,-0.060520498,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,docusate,DB11089
,32335,DB00678,10017577,227,15372,110,10614,0.002537102,1.424872133,1.128194055,1.808514658,0.011794785,DB0067810017577_,4.440097815,0.354082078,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,32336,DB01268,10017577,61,2082,61,3069,0.039814462,1.473917454,1.011743376,2.147335235,0.105326403,DB0126810017577_,2.250691154,0.387923791,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,32338,DB00190,10037844,43,3254,58,4616,0.839101266,1.051659677,0.690089779,1.591840756,0.917557016,DB0019010037844_,0.086040558,0.050369561,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,carbidopa,DB00190
,32339,DB01268,10037844,95,2048,147,2983,0.687913937,0.941304435,0.714913124,1.234689541,0.811850707,DB0126810037844_,0.208438814,-0.060488669,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sunitinib,DB01268
,32340,DB11089,10037844,248,9927,202,8205,0.885770022,1.014754498,0.83730598,1.230956309,0.952501279,DB1108910037844_,0.048663829,0.014646709,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,docusate,DB11089
,32341,DB00115,10037867,45,18380,15,10457,0.080184809,1.706770902,0.933238404,3.298123552,0.178705927,DB0011510037867_,1.722013688,0.534603224,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,32343,DB00316,10037867,84,65390,57,36896,0.292821292,0.831530242,0.58686952,1.185554667,0.45841618,DB0031610037867_,0.779977817,-0.18448761,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,32348,DB00115,10061225,51,18374,20,10452,0.174711579,1.45054269,0.849171566,2.570161916,0.317081672,DB0011510061225_,1.148595897,0.371937755,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,32350,DB00678,10061225,31,15568,24,10700,0.681756929,0.887777812,0.504003268,1.581691818,0.8075468,DB0067810061225_,0.213754269,-0.119033779,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,32354,DB00390,10007882,49,4096,23,3278,0.041997102,1.704851836,1.016600026,2.938404725,0.109687383,DB0039010007882_,2.210120931,0.533478207,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,digoxin,DB00390
,32355,DB00820,10007882,126,11789,51,5765,0.295474863,1.208119548,0.86466162,1.7098763,0.461347636,DB0082010007882_,0.77360343,0.189065059,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,tadalafil,DB00820
,32356,DB00390,10016807,145,4000,51,3250,1.13170835761078e-07,2.309749995,1.661822985,3.255056825,2.03120206075789e-06,DB0039010016807_,13.10688279,0.837139292,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,digoxin,DB00390
,32357,DB00421,10016807,329,8574,120,5132,2.81243074384426e-06,1.640979855,1.323510803,2.045710882,3.58075767023233e-05,DB0042110016807_,10.23735105,0.495293536,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,spironolactone,DB00421
,32358,DB00820,10016807,775,11140,258,5558,1.98595114923931e-08,1.498669926,1.29513695,1.738582055,4.16107819511799e-07,DB0082010016807_,14.69232143,0.404577999,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,tadalafil,DB00820
,32359,DB00390,10021097,194,3951,112,3189,0.005692763,1.398013125,1.096769819,1.788797554,0.022697654,DB0039010021097_,3.785493691,0.335052032,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,digoxin,DB00390
,32360,DB00390,10021143,74,4071,39,3262,0.035836301,1.520286553,1.015062245,2.30844952,0.097194156,DB0039010021143_,2.331044693,0.418898839,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,32361,DB00390,10030095,98,4047,38,3263,8.1202753824264e-05,2.079117831,1.411603308,3.118116747,0.000667735,DB0039010030095_,7.311619424,0.731943684,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,32362,DB00421,10030095,195,8708,88,5164,0.034655192,1.314049261,1.013976362,1.714137056,0.094753391,DB0042110030095_,2.356477649,0.273113409,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,32363,DB00390,10030124,169,3976,62,3239,3.69406762554112e-08,2.220269,1.643772599,3.032034402,7.3245692063459e-07,DB0039010030124_,14.12686131,0.79762836,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,32364,DB00390,10033318,80,4065,23,3278,3.31901350237377e-06,2.804429218,1.740708877,4.685112396,4.13558994595376e-05,DB0039010033318_,10.09329548,1.031200031,female,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,digoxin,DB00390
,32365,DB00421,10033318,151,8752,47,5205,5.89748254634569e-05,1.910618184,1.366170784,2.715520015,0.000508687,DB0042110033318_,7.583677987,0.647426846,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,spironolactone,DB00421
,32369,DB00695,10036142,42,28007,36,20492,0.493299974,0.853625587,0.533659086,1.371820168,0.656027818,DB0069510036142_,0.421552086,-0.158262604,NA,10036142,Polyuria,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,32372,DB00421,10038687,51,8852,30,5222,1,1.00286922,0.625794506,1.633107945,1,DB0042110038687_,0,0.002865111,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,32380,DB00108,10051055,54,10140,19,3276,0.784683367,0.918215188,0.534704853,1.642895022,0.883069052,DB0010810051055_,0.12435188,-0.085323507,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,natalizumab,DB00108
,32384,DB00188,10007882,43,7843,51,8777,0.836100258,0.943531084,0.613132224,1.446027464,0.915322586,DB0018810007882_,0.088478723,-0.058125969,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,bortezomib,DB00188
,32387,DB00188,10021097,116,7770,182,8646,0.004079588,0.709236142,0.555847734,0.902033509,0.017361285,DB0018810021097_,4.053512577,-0.343566744,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,bortezomib,DB00188
,32391,DB00188,10029354,156,7730,165,8663,0.6119133,1.05959835,0.843880856,1.329893869,0.753867548,DB0018810029354_,0.282538592,0.057889922,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,bortezomib,DB00188
,32397,DB00188,10040047,90,7796,137,8691,0.022829005,0.732367237,0.553995377,0.964264151,0.068496136,DB0018810040047_,2.68097795,-0.3114732,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,bortezomib,DB00188
,32408,DB00695,10000891,87,27962,100,20428,0.002279867,0.635608807,0.471009591,0.856297643,0.010826792,DB0069510000891_,4.525731477,-0.453171989,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,furosemide,DB00695
,32409,DB01109,10000891,38,4374,39,4231,0.819681381,0.942486025,0.585527361,1.515934956,0.903936442,DB0110910000891_,0.100996228,-0.059234187,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,heparin,DB01109
,32410,DB01136,10000891,32,9852,68,11047,0.002490256,0.527685535,0.335068519,0.815360101,0.011627386,DB0113610000891_,4.454392095,-0.63925475,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,carvedilol,DB01136
,32412,DB00390,10001053,61,4084,41,3260,0.423200866,1.18759326,0.784183443,1.814903445,0.592082178,DB0039010001053_,0.52410984,0.171928789,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,32413,DB00695,10001053,257,27792,195,20333,0.70225407,0.964210701,0.796632285,1.168633563,0.821369191,DB0069510001053_,0.196782586,-0.036445438,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,32414,DB00758,10001053,34,8266,47,10027,0.578096334,0.877536569,0.546759437,1.395068387,0.726924,DB0075810001053_,0.318933346,-0.13063665,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,32415,DB01109,10001053,42,4370,47,4223,0.523474228,0.863572575,0.554468878,1.341074884,0.681717293,DB0110910001053_,0.383140234,-0.146677337,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,heparin,DB01109
,32416,DB01136,10001053,63,9821,67,11048,0.791680518,1.057803593,0.736992239,1.516571228,0.887231487,DB0113610001053_,0.119649354,0.056194676,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,32418,DB00390,10002034,139,4006,66,3235,0.000352092,1.700605036,1.254869447,2.32419915,0.002304358,DB0039010002034_,6.072952984,0.530984091,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,digoxin,DB00390
,32419,DB01109,10002034,108,4304,108,4162,0.836348439,0.967002346,0.731105082,1.279083815,0.915518021,DB0110910002034_,0.088265231,-0.033554357,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,heparin,DB01109
,32426,DB00695,10007625,51,27998,43,20485,0.531055033,0.86778687,0.566713821,1.334364451,0.687912749,DB0069510007625_,0.374093268,-0.141809136,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,furosemide,DB00695
,32427,DB01109,10007625,25,4387,33,4237,0.29177363,0.731702254,0.416344524,1.270933373,0.457206032,DB0110910007625_,0.782621154,-0.312381605,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,heparin,DB01109
,32430,DB01109,10035664,123,4289,135,4135,0.312399428,0.878410741,0.679723271,1.134329708,0.47991634,DB0110910035664_,0.734143481,-0.12964098,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,heparin,DB01109
,32432,DB00695,10038540,31,28018,26,20502,0.687687823,0.872468365,0.501157167,1.530335279,0.811687484,DB0069510038540_,0.208639884,-0.136428884,NA,10038540,Renal tubular necrosis,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,32437,DB00390,10040047,79,4066,55,3246,0.482981747,1.14665445,0.79985224,1.653870903,0.647177153,DB0039010040047_,0.435135215,0.136848529,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,digoxin,DB00390
,32438,DB00758,10040047,64,8236,110,9964,0.026421151,0.703904302,0.508216942,0.968010953,0.07669151,DB0075810040047_,2.567964274,-0.351112867,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,clopidogrel,DB00758
,32439,DB01109,10040047,97,4315,121,4149,0.063864256,0.770838754,0.581903148,1.018917073,0.150422963,DB0110910040047_,1.894304196,-0.260276066,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,heparin,DB01109
,32440,DB01136,10040047,123,9761,151,10964,0.50289467,0.914992439,0.714033542,1.170615935,0.664033677,DB0113610040047_,0.409422412,-0.088839478,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,carvedilol,DB01136
,32441,DB00758,10042772,88,8212,122,9952,0.364840511,0.874160647,0.65581118,1.161246937,0.534401384,DB0075810042772_,0.626608066,-0.134491114,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,32442,DB01109,10042772,33,4379,36,4234,0.630857631,0.886326326,0.534465867,1.465485996,0.769702826,DB0110910042772_,0.26175078,-0.120670083,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,heparin,DB01109
,32443,DB01136,10042772,109,9775,130,10985,0.695876734,0.94223638,0.722577686,1.226750251,0.81696388,DB0113610042772_,0.202160395,-0.059499102,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,32444,DB01275,10042772,27,3952,40,3309,0.025954836,0.565227346,0.332768198,0.946384952,0.075592562,DB0127510042772_,2.582397392,-0.570527246,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,hydralazine,DB01275
,32466,DB00588,10013781,81,16443,32,8436,0.232478078,1.298670377,0.85188605,2.023061795,0.388906415,DB0058810013781_,0.944416543,0.261340954,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,32468,DB01409,10013781,35,5996,19,3947,0.577688644,1.212558717,0.673779565,2.247408232,0.726602833,DB0140910013781_,0.319375261,0.192732769,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,tiotropium,DB01409
,32475,DB00688,10022611,32,6458,32,5346,0.453340409,0.827826372,0.490301978,1.397618467,0.620886445,DB0068810022611_,0.476607072,-0.188951842,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolate mofetil,DB00688
,32477,DB00635,10035742,103,32950,131,23663,1.43470508804188e-05,0.564670296,0.431662061,0.736970935,0.000149263,DB0063510035742_,8.809802662,-0.571513266,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,32480,DB00688,10037400,46,6444,9,5369,8.13068083266851e-06,4.257963286,2.056880811,9.904009127,9.07494461514615e-05,DB0068810037400_,9.307408188,1.448790944,female,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolate mofetil,DB00688
,32482,DB01050,10000081,365,17743,141,9230,0.002830081,1.346620586,1.103912277,1.650125276,0.012885619,DB0105010000081_,4.351643373,0.297598185,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,32483,DB01050,10021789,159,17949,61,9310,0.045689149,1.351995585,0.999253856,1.849411527,0.116885423,DB0105010021789_,2.146561115,0.301581712,NA,10021789,Infection,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,32495,DB01104,10000081,233,15230,76,7210,0.004676081,1.451346294,1.113915208,1.908914904,0.019378083,DB0110410000081_,3.943612613,0.372491605,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,32501,DB01104,10012374,78,15385,30,7256,0.408200895,1.226198481,0.794542941,1.937687129,0.577618935,DB0110410012374_,0.54884091,0.203918718,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,32525,DB00264,10007739,128,29479,85,24807,0.098071823,1.267214691,0.955280005,1.688209327,0.207955072,DB0026410007739_,1.570433223,0.236821335,NA,10007739,Cataract,10015919,Eye disorders,Eye,metoprolol,DB00264
,32526,DB00338,10007739,151,33523,69,22203,0.010571564,1.449417996,1.082616304,1.95717375,0.037205153,DB0033810007739_,3.291308002,0.371162094,NA,10007739,Cataract,10015919,Eye disorders,Eye,omeprazole,DB00338
,32527,DB00455,10007739,44,9357,17,5101,0.282459701,1.41095343,0.78908277,2.636925949,0.446543364,DB0045510007739_,0.806218764,0.344265667,NA,10007739,Cataract,10015919,Eye disorders,Eye,loratadine,DB00455
,32528,DB00563,10007739,90,46556,22,15326,0.229200288,1.34668388,0.83719916,2.255849426,0.384917073,DB0056310007739_,0.954727363,0.297645186,NA,10007739,Cataract,10015919,Eye disorders,Eye,methotrexate,DB00563
,32529,DB00999,10007739,135,21295,33,12206,3.59999895441335e-06,2.344797237,1.591489803,3.545352945,4.43524595813241e-05,DB0099910007739_,10.02334239,0.852198932,NA,10007739,Cataract,10015919,Eye disorders,Eye,hydrochlorothiazide,DB00999
,32530,DB01373,10007739,159,22561,46,7335,0.515624248,1.123773864,0.803898909,1.597991186,0.675362934,DB0137310007739_,0.392505052,0.116692543,NA,10007739,Cataract,10015919,Eye disorders,Eye,calcium,DB01373
,32535,DB00563,10008629,34,46612,19,15329,0.078158193,0.588499461,0.326161351,1.092521315,0.175275741,DB0056310008629_,1.741394885,-0.530179269,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,methotrexate,DB00563
,32536,DB00761,10008629,37,15270,21,8604,1,0.992757832,0.565675184,1.786228571,1,DB0076110008629_,0,-0.00726852,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,potassium chloride,DB00761
,32537,DB00999,10008629,54,21376,32,12207,0.910732169,0.963695694,0.610776792,1.543101455,0.959789711,DB0099910008629_,0.04104107,-0.036979705,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,hydrochlorothiazide,DB00999
,32538,DB01373,10008629,42,22678,13,7368,1,1.049630807,0.552380322,2.132473703,1,DB0137310008629_,0,0.04843849,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,calcium,DB01373
,32542,DB00264,10013538,110,29497,48,24844,0.000110581,1.930115857,1.362620686,2.770071863,0.000869338,DB0026410013538_,7.047778004,0.65758003,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,metoprolol,DB00264
,32543,DB00338,10013538,142,33532,49,22223,4.30812288843911e-05,1.920566983,1.378303743,2.716113665,0.000389204,DB0033810013538_,7.851405991,0.652620446,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,omeprazole,DB00338
,32545,DB00563,10013538,141,46505,30,15318,0.032735523,1.548051035,1.037497731,2.380065719,0.090702916,DB0056310013538_,2.400165775,0.436996743,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,methotrexate,DB00563
,32546,DB00761,10013538,48,15259,18,8607,0.158129473,1.504137085,0.858386691,2.749377507,0.294960309,DB0076110013538_,1.220914478,0.408219368,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,32547,DB00999,10013538,104,21326,31,12208,0.001162765,1.920431099,1.274248776,2.970141405,0.00624186,DB0099910013538_,5.076477056,0.652549691,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,32550,DB00264,10017885,185,29422,80,24812,3.2471048286404e-07,1.950109744,1.491599203,2.569235958,5.24586050527431e-06,DB0026410017885_,12.15807127,0.66788565,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,32551,DB00455,10017885,84,9317,22,5096,0.001458622,2.088287349,1.29150304,3.512564816,0.007514678,DB0045510017885_,4.890897143,0.73634428,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,32552,DB00563,10017885,159,46487,35,15313,0.030129838,1.496389917,1.031919535,2.225276783,0.084980688,DB0056310017885_,2.46533125,0.403055485,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,32553,DB00761,10017885,127,15180,33,8592,3.0820193959357e-05,2.178207883,1.473702669,3.302562137,0.000290466,DB0076110017885_,8.144025109,0.778502467,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,32554,DB00999,10017885,175,21255,75,12164,0.040553632,1.335329615,1.012229798,1.77606254,0.106745552,DB0099910017885_,2.237307294,0.289178164,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,32555,DB01373,10017885,225,22495,29,7352,2.1916728674151e-07,2.535807183,1.71604686,3.877272967,3.68220654010904e-06,DB0137310017885_,12.51199838,0.930512002,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,32558,DB00126,10017944,47,10124,25,5920,0.806785534,1.099334983,0.662233463,1.865878058,0.895595488,DB0012610017944_,0.110266432,0.094705436,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,32559,DB00264,10017944,123,29484,80,24812,0.077609931,1.293861856,0.968039638,1.73756246,0.174297423,DB0026410017944_,1.74699211,0.257631433,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,32560,DB00455,10017944,47,9354,22,5096,0.614690623,1.163848165,0.686707661,2.030492921,0.75615505,DB0045510017944_,0.279508832,0.151731899,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,32561,DB00563,10017944,654,45992,144,15204,5.39243206527089e-06,1.501329732,1.250457951,1.81270122,6.316691214782e-05,DB0056310017944_,9.669729936,0.406351203,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,32562,DB00761,10017944,60,15247,34,8591,1,0.994331928,0.641706972,1.563557725,1,DB0076110017944_,0,-0.005684197,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,32563,DB01373,10017944,99,22621,31,7350,0.918852122,1.037664709,0.686364363,1.609024508,0.964166805,DB0137310017944_,0.036490966,0.036972716,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,32566,DB00005,10019909,70,128012,43,42376,0.002117434,0.538909717,0.363423794,0.807351355,0.010194477,DB0000510019909_,4.585909155,-0.618207223,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,32568,DB00338,10019909,49,33625,43,22229,0.200628901,0.753345953,0.489719083,1.162641545,0.349747871,DB0033810019909_,1.050542752,-0.283230724,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,32573,DB01373,10019909,34,22686,25,7356,0.003449165,0.440993173,0.25529336,0.771589853,0.015140497,DB0137310019909_,4.190382232,-0.818725884,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,32580,DB00563,10020096,76,46570,18,15330,0.232657801,1.389850699,0.822904446,2.470291425,0.389132404,DB0056310020096_,0.943835622,0.32919633,NA,10020096,Hip arthroplasty,10042613,Surgical and medical procedures,Surg,methotrexate,DB00563
,32586,DB00761,10020772,210,15097,118,8507,1,1.002820076,0.795300949,1.269431437,1,DB0076110020772_,0,0.002816107,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,potassium chloride,DB00761
,32587,DB01373,10020772,354,22366,72,7309,0.000172891,1.606639735,1.242049195,2.10299057,0.001276172,DB0137310020772_,6.663890592,0.474144877,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,calcium,DB01373
,32590,DB00005,10025409,65,128017,11,42408,0.033944047,1.957379556,1.024966096,4.113825597,0.093289342,DB0000510025409_,2.372049406,0.671606618,NA,10025409,Macular degeneration,10015919,Eye disorders,Eye,etanercept,DB00005
,32592,DB00264,10025409,36,29571,16,24876,0.036058815,1.892718957,1.023628603,3.654037039,0.097643545,DB0026410025409_,2.326431732,0.638014397,NA,10025409,Macular degeneration,10015919,Eye disorders,Eye,metoprolol,DB00264
,32601,DB00563,10033645,69,46577,90,15258,1.23315531348916e-17,0.251165839,0.180749137,0.347724959,1.01929205707744e-15,DB0056310033645_,34.51966807,-1.381641846,male,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,32602,DB00999,10033645,111,21319,78,12161,0.172178686,0.811782648,0.601674603,1.099774663,0.313708576,DB0099910033645_,1.159290825,-0.20852265,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,32605,DB00005,10043709,68,128014,11,42408,0.026051706,2.047758551,1.07528353,4.295197835,0.075834597,DB0000510043709_,2.579200661,0.716745805,NA,10043709,Thyroid disorder,10014698,Endocrine disorders,Endo,etanercept,DB00005
,32608,DB00338,10043709,42,33632,18,22254,0.146241455,1.54393347,0.869435815,2.85025531,0.278729364,DB0033810043709_,1.277513991,0.434333361,NA,10043709,Thyroid disorder,10014698,Endocrine disorders,Endo,omeprazole,DB00338
,32616,DB00264,10047531,51,29556,22,24870,0.009240149,1.950588415,1.161558143,3.378510371,0.033414445,DB0026410047531_,3.398766994,0.668131078,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,metoprolol,DB00264
,32617,DB00338,10047531,34,33640,20,22252,0.781251002,1.124531953,0.628814066,2.062372271,0.880865741,DB0033810047531_,0.126850058,0.117366907,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,omeprazole,DB00338
,32623,DB00455,10047895,181,9220,113,5005,0.266934087,0.869521571,0.681825151,1.112734837,0.429174693,DB0045510047895_,0.845891232,-0.139812137,NA,10047895,Weight decreased,10022891,Investigations,Inv,loratadine,DB00455
,32624,DB00761,10047895,409,14898,258,8367,0.152397672,0.890326154,0.758180642,1.047011208,0.287312674,DB0076110047895_,1.2471842,-0.116167419,NA,10047895,Weight decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,32628,DB00451,10061016,54,47217,19,15400,0.785887528,0.926956511,0.54055021,1.656531942,0.883799408,DB0045110061016_,0.123525156,-0.075848628,NA,10061016,Blood test abnormal,10022891,Investigations,Inv,levothyroxine,DB00451
,32632,DB09072,10013395,44,6427,15,2520,0.77158328,1.150126125,0.626508481,2.229268075,0.875013656,DB0907210013395_,0.133515786,0.13987161,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,32634,DB09072,10013496,49,6422,22,2513,0.597160295,0.8715831,0.515902366,1.517087464,0.742442985,DB0907210013496_,0.297809199,-0.137444066,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,32638,DB00537,10022116,81,7476,29,4269,0.035875348,1.594879334,1.030057894,2.533219983,0.097285003,DB0053710022116_,2.330110438,0.466798081,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,ciprofloxacin,DB00537
,32645,DB00682,10012378,164,19295,76,16288,1.17167968991926e-05,1.821566586,1.378401467,2.425608701,0.000124712,DB0068210012378_,8.98950438,0.599696892,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,32646,DB00956,10012378,155,5659,44,3423,3.75431795654783e-06,2.130657741,1.511143644,3.05854543,4.59316668256517e-05,DB0095610012378_,9.98835577,0.756430731,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,hydrocodone,DB00956
,32658,DB00254,10002034,64,5871,55,3333,0.027224598,0.660663291,0.452293894,0.967683183,0.078494879,DB0025410002034_,2.544721895,-0.414510962,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,doxycycline,DB00254
,32659,DB00285,10002034,92,10859,35,3683,0.540528616,0.891515566,0.596826148,1.358724677,0.696051081,DB0028510002034_,0.362332229,-0.114832381,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,venlafaxine,DB00285
,32664,DB01224,10002034,55,8053,47,5870,0.423059778,0.853005248,0.566470099,1.288937223,0.591936882,DB0122410002034_,0.524355268,-0.158989579,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,quetiapine,DB01224
,32667,DB13961,10002034,134,9323,121,6293,0.024181152,0.747543502,0.578992794,0.965973864,0.071645333,DB1396110002034_,2.636027257,-0.290962778,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,fish oil,DB13961
,32672,DB00787,10012378,135,16865,84,17164,0.000401533,1.635601919,1.235440034,2.175976102,0.002571081,DB0078710012378_,5.963428753,0.492010883,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,acyclovir,DB00787
,32677,DB00008,10013573,63,1462,44,1632,0.018311425,1.598058903,1.062738822,2.421329935,0.057621909,DB0000810013573_,2.853852415,0.468789707,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,peginterferon alfa-2a,DB00008
,32678,DB00254,10013573,151,5784,50,3338,0.000613045,1.742773343,1.254097051,2.457347237,0.003664745,DB0025410013573_,5.608996514,0.55547772,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,doxycycline,DB00254
,32681,DB00811,10013573,115,2683,137,4019,0.077493012,1.257347833,0.967809412,1.631224486,0.174101783,DB0081110013573_,1.74811519,0.229004608,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ribavirin,DB00811
,32682,DB01048,10013573,14,451,43,1092,0.552557781,0.788455641,0.394284202,1.486798068,0.706384966,DB0104810013573_,0.347594913,-0.237679131,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,abacavir,DB01048
,32684,DB01156,10013573,457,13165,146,6182,4.23803505252815e-05,1.469818305,1.214187005,1.787689981,0.000383574,DB0115610013573_,7.865977055,0.385138791,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,32685,DB06413,10013573,61,1495,21,653,0.392702212,1.268603386,0.754144534,2.21276471,0.562654473,DB0641310013573_,0.575089564,0.237916599,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,armodafinil,DB06413
,32691,DB00190,10016322,92,3205,98,4576,0.052328434,1.340285482,0.993564257,1.806729491,0.129399586,DB0019010016322_,2.044850099,0.292882637,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,32692,DB00715,10016322,84,4759,44,2243,0.567632403,0.899805702,0.615271473,1.331819533,0.718752656,DB0071510016322_,0.330237992,-0.105576426,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,32695,DB08865,10010774,66,1145,41,930,0.196000227,1.30732765,0.863134164,2.000228419,0.344259034,DB0886510010774_,1.066360898,0.267985092,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,crizotinib,DB08865
,32699,DB08865,10048959,44,1167,23,948,0.104293462,1.553733398,0.910610451,2.716306959,0.217470442,DB0886510048959_,1.525692335,0.440660678,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,crizotinib,DB08865
,32707,DB01238,10010305,90,5160,43,3459,0.07442972,1.403002565,0.962485708,2.073016884,0.168886844,DB0123810010305_,1.778526352,0.338614629,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,32725,DB00285,10002855,338,10613,105,3613,0.437905031,1.095857688,0.874794152,1.382073218,0.606365534,DB0028510002855_,0.500272284,0.091537334,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,32726,DB00776,10002855,48,1857,41,1298,0.382906256,0.818371249,0.524729478,1.281507697,0.552980733,DB0077610002855_,0.592432119,-0.200439196,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,oxcarbazepine,DB00776
,32727,DB00820,10002855,193,11722,70,5746,0.034032462,1.3515247,1.021058034,1.806359172,0.093468221,DB0082010002855_,2.37013378,0.301233363,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,tadalafil,DB00820
,32728,DB00996,10002855,714,38239,268,22157,7.00998829665787e-10,1.543706648,1.338254426,1.784819498,2.00497869834224e-08,DB0099610002855_,17.72504731,0.434186439,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,32732,DB00451,10005746,66,47205,25,15394,0.542526173,0.860955089,0.535683278,1.424687505,0.697734634,DB0045110005746_,0.359916429,-0.149712938,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,32751,DB00285,10031161,45,10906,8,3710,0.112013027,1.91354407,0.891592825,4.704709766,0.229100057,DB0028510031161_,1.473596441,0.648957057,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,venlafaxine,DB00285
,32752,DB00425,10031161,45,12650,10,7474,0.003083816,2.658612951,1.319847276,5.919489444,0.0138348,DB0042510031161_,4.280568147,0.97780454,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,32753,DB00476,10031161,67,17190,19,6158,0.461646973,1.263213029,0.749025021,2.22901369,0.62887854,DB0047610031161_,0.463817141,0.233658498,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,32754,DB00482,10031161,74,8185,16,3055,0.05584748,1.72623382,0.994044197,3.180883676,0.135808217,DB0048210031161_,1.996511559,0.545942052,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,32755,DB00641,10031161,48,14076,23,12452,0.016726676,1.846129525,1.10045147,3.182258739,0.053689178,DB0064110031161_,2.924543826,0.613091299,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,32758,DB00996,10031161,139,38814,31,22394,2.36401613745635e-07,2.586953104,1.741869844,3.953426668,3.94596412924267e-06,DB0099610031161_,12.44281724,0.950480776,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,32760,DB08908,10016766,49,10624,10,3269,0.282193429,1.507659133,0.75337689,3.342101948,0.446229766,DB0890810016766_,0.806921288,0.410558205,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,32762,DB01261,10020772,97,3684,100,3203,0.24703602,0.843374555,0.628523151,1.131249195,0.406176573,DB0126110020772_,0.900967304,-0.170344108,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,sitagliptin,DB01261
,32764,DB01261,10033609,82,3699,86,3217,0.240908381,0.829267845,0.602872595,1.140010648,0.398958971,DB0126110033609_,0.918896696,-0.187212081,NA,10033609,Pancreatic carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sitagliptin,DB01261
,32775,DB00065,10043414,121,9343,56,4901,0.474106045,1.133413757,0.817441189,1.588132052,0.639808876,DB0006510043414_,0.446585778,0.125234102,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,32776,DB00158,10043414,70,16745,24,8080,0.153323759,1.407381958,0.87333545,2.342094761,0.288638495,DB0015810043414_,1.242580255,0.341731211,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,32778,DB00999,10043414,57,21373,17,12222,0.015572301,1.917320588,1.098916337,3.517519269,0.050768117,DB0099910043414_,2.980486738,0.650928684,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,32785,DB00065,10060933,128,9336,47,4910,0.037193352,1.432262249,1.015828259,2.049551267,0.099936341,DB0006510060933_,2.303221887,0.359255187,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,32786,DB00158,10060933,61,16754,13,8091,0.005849439,2.265990173,1.230748664,4.498580384,0.023204424,DB0015810060933_,3.763412341,0.818011826,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,32788,DB00563,10060933,204,46442,37,15311,0.00054566,1.817591475,1.275043367,2.656279376,0.003317375,DB0056310060933_,5.708581386,0.597512259,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,32789,DB00635,10060933,116,32937,58,23736,0.025366186,1.441286617,1.042345562,2.011832734,0.074302134,DB0063510060933_,2.599615603,0.365536199,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,32790,DB00999,10060933,67,21363,19,12220,0.006682741,2.017072853,1.196530232,3.55780362,0.025820349,DB0099910060933_,3.656592372,0.701647378,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,32799,DB00005,10039722,38,128044,18,42401,0.216766761,0.699083585,0.389253986,1.301376676,0.369585464,DB0000510039722_,0.99537327,-0.357984966,NA,10039722,Scoliosis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,32800,DB00005,10068945,420,127662,143,42276,0.769662148,0.972623949,0.802389616,1.184676791,0.873852947,DB0000510068945_,0.134843171,-0.027757757,NA,10068945,Incorrect dose administered by device,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,32808,DB00264,10005557,200,29407,215,24677,0.013304393,0.780616032,0.640146202,0.951531137,0.044690858,DB0026410005557_,3.107986312,-0.247671886,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,metoprolol,DB00264
,32815,DB00331,10013710,146,24800,162,20590,0.011502031,0.748252989,0.59367615,0.942384081,0.039832791,DB0033110013710_,3.223064817,-0.290014138,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,32817,DB01115,10013710,33,3567,40,2228,0.005243833,0.515355721,0.313922572,0.840892637,0.021254304,DB0111510013710_,3.851195874,-0.662897896,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,32832,DB00047,10033645,83,9202,62,8456,0.242633163,1.230165584,0.87338537,1.74053023,0.400855605,DB0004710033645_,0.914154003,0.207148781,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,32836,DB01069,10003988,170,6530,45,2350,0.071565157,1.359462196,0.970005857,1.939609533,0.163993736,DB0106910003988_,1.80792705,0.307089178,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,promethazine,DB01069
,32837,DB00331,10008629,61,24885,66,20686,0.153229867,0.768298438,0.533131721,1.105656651,0.2885134,DB0033110008629_,1.243013746,-0.26357703,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,metformin,DB00331
,32843,DB01069,10013968,332,6368,95,2300,0.049039937,1.262181828,0.996601375,1.610867344,0.123179773,DB0106910013968_,2.094110418,0.232841833,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,promethazine,DB01069
,32844,DB01069,10016322,113,6587,25,2370,0.031593584,1.626286696,1.044170975,2.62545042,0.088213599,DB0106910016322_,2.427994145,0.486299315,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,32845,DB00331,10019303,131,24815,73,20679,0.005898337,1.495405477,1.114023271,2.020678356,0.023352581,DB0033110019303_,3.75704775,0.402397392,NA,10019303,Heart rate increased,10022891,Investigations,Inv,metformin,DB00331
,32846,DB01069,10019303,40,6660,10,2385,0.339281244,1.432341493,0.702540157,3.217298657,0.508363324,DB0106910019303_,0.676558882,0.359310513,NA,10019303,Heart rate increased,10022891,Investigations,Inv,promethazine,DB01069
,32847,DB00331,10020642,171,24775,123,20629,0.239878969,1.157587863,0.912106508,1.472721243,0.397730316,DB0033110020642_,0.9219811,0.146338412,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,32848,DB01069,10020642,64,6636,14,2381,0.094578374,1.640228277,0.907913026,3.173548122,0.202599124,DB0106910020642_,1.59652601,0.494835426,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,promethazine,DB01069
,32849,DB00331,10022086,304,24642,122,20630,1.20760531450251e-12,2.086033864,1.684020121,2.597553119,5.3799840155421e-11,DB0033110022086_,23.64575062,0.73526459,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,32850,DB01069,10022086,49,6651,10,2385,0.10497723,1.757083896,0.87744713,3.89686028,0.218493376,DB0106910022086_,1.52099958,0.563655557,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,32851,DB01069,10022437,137,6563,34,2361,0.053961015,1.44945291,0.986262406,2.183703762,0.132421369,DB0106910022437_,2.021766251,0.371186182,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,promethazine,DB01069
,32852,DB01069,10027175,72,6628,21,2374,0.477978075,1.228001055,0.744546312,2.107684209,0.643286259,DB0106910027175_,0.441165461,0.205387689,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,32853,DB00331,10037087,479,24467,262,20490,2.69501642299263e-08,1.531053506,1.312711841,1.788873029,5.48710353821544e-07,DB0033110037087_,14.41569512,0.425956064,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,32854,DB01069,10037087,132,6568,30,2365,0.024083435,1.584346599,1.055847489,2.447487216,0.071436337,DB0106910037087_,2.638948616,0.460172082,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,promethazine,DB01069
,32858,DB01069,10042772,65,6635,20,2375,0.621743447,1.163315695,0.693889866,2.03238872,0.761995921,DB0106910042772_,0.271814076,0.151274286,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,32859,DB00331,10047513,227,24719,134,20618,0.001438386,1.412968946,1.135354739,1.764067128,0.007427726,DB0033110047513_,4.902535462,0.345693126,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,metformin,DB00331
,32860,DB01069,10047513,62,6638,11,2384,0.031826449,2.024202194,1.054474068,4.270437714,0.088717134,DB0106910047513_,2.422302243,0.705175645,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,promethazine,DB01069
,32861,DB00331,10050584,139,24807,88,20664,0.045075214,1.315737065,0.999539367,1.739713049,0.115725522,DB0033110050584_,2.156534084,0.274397014,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,32862,DB01069,10050584,76,6624,7,2388,7.62851288048328e-05,3.913839507,1.806454134,10.07760626,0.000632242,DB0106910050584_,7.366238771,1.364518863,female,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,promethazine,DB01069
,32870,DB00060,10012378,311,9197,77,2388,0.749887911,1.048735965,0.811136532,1.369667921,0.858372327,DB0006010012378_,0.152717326,0.047585596,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,interferon beta-1a,DB00060
,32871,DB00060,10042458,82,9426,23,2442,0.716786091,0.923637737,0.574321541,1.540760122,0.832555122,DB0006010042458_,0.183255847,-0.079435343,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,interferon beta-1a,DB00060
,32873,DB00060,10037087,66,9442,8,2457,0.042135808,2.14665664,1.026435393,5.185159374,0.109967702,DB0006010037087_,2.207568579,0.763911581,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,interferon beta-1a,DB00060
,32899,DB01069,10013709,280,6420,72,2323,0.011256017,1.407048368,1.077352864,1.857547748,0.039126321,DB0106910013709_,3.24095988,0.341494154,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,32904,DB00005,10049119,51,128031,10,42409,0.139634979,1.689254168,0.84791177,3.732399125,0.269301154,DB0000510049119_,1.311924994,0.524287111,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,32907,DB01104,10049119,46,15417,17,7269,0.420714224,1.275751164,0.716989845,2.37545157,0.589690896,DB0110410049119_,0.528156784,0.243535154,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,32910,DB01050,10049438,77,18031,19,9352,0.002437788,2.101896663,1.258511179,3.68093241,0.011433976,DB0105010049438_,4.471165993,0.74284011,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,32912,DB01104,10049438,37,15426,16,7270,0.883126505,1.089834136,0.591062858,2.099836854,0.951117766,DB0110410049438_,0.050117391,0.086025516,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,32920,DB00005,10064882,62,128020,26,42393,0.32386926,0.789650819,0.492064403,1.300991122,0.492317016,DB0000510064882_,0.708632429,-0.236164432,NA,10064882,Procedural pain,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,32922,DB01050,10064882,57,18051,12,9359,0.003141461,2.462688971,1.305720365,5.045291241,0.014046664,DB0105010064882_,4.265370357,0.901253831,NA,10064882,Procedural pain,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,32925,DB00005,10069803,312,127770,72,42347,0.005386073,1.436171954,1.108049291,1.882939108,0.021703654,DB0000510069803_,3.830274633,0.361981208,NA,10069803,Injury associated with device,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,32933,DB00169,10000059,586,38105,180,17995,2.42713318812345e-07,1.537417892,1.297465818,1.828944427,4.04163420017895e-06,DB0016910000059_,12.41886144,0.430104315,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,32935,DB00999,10000059,307,21123,134,12105,0.009485491,1.312923339,1.066976399,1.622674967,0.034128553,DB0099910000059_,3.377620913,0.272256207,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,32937,DB00169,10003041,35,38656,22,18153,0.31962414,0.747076097,0.42601472,1.337308178,0.487823652,DB0016910003041_,0.717801307,-0.291588229,NA,10003041,Application site erythema,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,32939,DB00989,10003041,45,789,38,840,0.31323742,1.260581665,0.790893566,2.018401973,0.480835481,DB0098910003041_,0.732230102,0.231573254,NA,10003041,Application site erythema,10018065,General disorders and administration site conditions,Genrl,rivastigmine,DB00989
,32952,DB00169,10027175,577,38114,195,17980,4.4095930687074e-05,1.395886894,1.183454416,1.652109011,0.000397143,DB0016910027175_,7.831214406,0.333529979,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,32953,DB00264,10027175,285,29322,159,24733,2.46832257555669e-05,1.511912385,1.240020154,1.84881933,0.000238924,DB0026410027175_,8.339364328,0.41337533,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,32954,DB00999,10027175,229,21201,86,12153,0.000769182,1.526366849,1.184959186,1.981335066,0.004425714,DB0099910027175_,5.420323668,0.422890303,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,32956,DB00169,10027374,45,38646,16,18159,0.410027592,1.321584266,0.732501426,2.505353851,0.579408379,DB0016910027374_,0.545747732,0.278831218,NA,10027374,Mental impairment,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,32957,DB00264,10027374,32,29575,20,24872,0.331126931,1.345559531,0.746104277,2.483027358,0.499837557,DB0026410027374_,0.693472119,0.296809935,NA,10027374,Mental impairment,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,32968,DB00619,10013709,97,2802,124,2370,0.002996423,0.661711717,0.499070175,0.875275887,0.013498027,DB0061910013709_,4.305211784,-0.412925291,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,32971,DB00193,10008190,171,19149,70,8632,0.529642411,1.101186673,0.828113276,1.47768983,0.686895313,DB0019310008190_,0.375573381,0.096388392,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,32972,DB00215,10008190,88,11015,44,5232,0.779575091,0.949980909,0.653229563,1.399260668,0.87999533,DB0021510008190_,0.127838678,-0.05131339,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,32973,DB00497,10008190,126,19141,114,16261,0.649424891,0.938988182,0.722323141,1.221645425,0.784277843,DB0049710008190_,0.24299193,-0.062952386,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,32979,DB00497,10008629,36,19231,25,16350,0.520652113,1.2242654,0.714544283,2.128520287,0.679729842,DB0049710008629_,0.38605985,0.202340991,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,oxycodone,DB00497
,32983,DB00005,10009033,229,127853,72,42347,0.738921624,1.053425419,0.804842607,1.393055168,0.849779265,DB0000510009033_,0.162778652,0.052047159,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,32984,DB00158,10005425,56,16759,13,8091,0.014246883,2.079637684,1.122456748,4.147391599,0.047238097,DB0015810005425_,3.052554576,0.732193688,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,folic acid,DB00158
,32985,DB00169,10005425,168,38523,49,18126,0.002715074,1.613212983,1.166572296,2.266716889,0.0124591,DB0016910005425_,4.385303965,0.478227832,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,32986,DB00563,10005425,111,46535,22,15326,0.026857682,1.661614654,1.044441855,2.759357906,0.077696915,DB0056310005425_,2.554939726,0.507789813,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,methotrexate,DB00563
,32987,DB01373,10005425,124,22596,9,7372,1.40191510992472e-07,4.494973273,2.291051732,10.06683819,2.46820204022799e-06,DB0137310005425_,12.91202059,1.502959722,female,10005425,Blood cholesterol increased,10022891,Investigations,Inv,calcium,DB01373
,32988,DB00158,10013774,74,16741,8,8096,2.35660450028078e-06,4.473638385,2.154462456,10.75132947,3.05440578352467e-05,DB0015810013774_,10.3963404,1.498202034,female,10013774,Dry eye,10015919,Eye disorders,Eye,folic acid,DB00158
,32989,DB00169,10013774,181,38510,30,18145,4.77427817566514e-09,2.842719624,1.923182808,4.337020827,1.15235906195921e-07,DB0016910013774_,15.97628445,1.044761208,female,10013774,Dry eye,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,32991,DB01373,10013774,101,22619,9,7372,1.76170595679867e-05,3.657546994,1.850783121,8.233479837,0.000178514,DB0137310013774_,8.630845483,1.296792702,female,10013774,Dry eye,10015919,Eye disorders,Eye,calcium,DB01373
,32992,DB08895,10013774,245,27869,32,6614,0.00092226,1.816967474,1.252343388,2.718160617,0.005155551,DB0889510013774_,5.26768132,0.597168888,NA,10013774,Dry eye,10015919,Eye disorders,Eye,tofacitinib,DB08895
,32993,DB00158,10013786,89,16726,26,8078,0.02183454,1.653181054,1.056741554,2.669278464,0.066244009,DB0015810013786_,2.714410248,0.502701344,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,32994,DB00169,10013786,264,38427,85,18090,0.002225743,1.462125365,1.140167114,1.890890933,0.010613872,DB0016910013786_,4.545593422,0.379891107,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,32995,DB00563,10013786,108,46538,23,15325,0.067400693,1.546229174,0.97851964,2.543302835,0.156697968,DB0056310013786_,1.8534351,0.435819176,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,32996,DB00788,10013786,46,9310,12,5049,0.026419404,2.078799797,1.082443335,4.315178206,0.07669151,DB0078810013786_,2.567964274,0.731790706,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,naproxen,DB00788
,32997,DB01373,10013786,146,22574,35,7346,0.118416325,1.357429873,0.932277065,2.025348262,0.238840785,DB0137310013786_,1.431958121,0.305593113,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,32998,DB08895,10013786,100,28014,17,6629,0.239024336,1.391933425,0.826570846,2.485586601,0.396751266,DB0889510013786_,0.924445728,0.330693734,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,33000,DB00169,10015929,46,38645,12,18163,0.06791667,1.801634928,0.938921967,3.737102581,0.157563078,DB0016910015929_,1.847929403,0.588694546,NA,10015929,Eye infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,33005,DB00158,10027599,113,16702,12,8092,2.19730945147871e-09,4.562617379,2.510055323,9.096566039,5.69307825846406e-08,DB0015810027599_,16.68142965,1.517896446,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,33006,DB00788,10027599,118,9238,15,5046,3.9506355458083e-10,4.296449065,2.498679839,7.929547652,1.18204274697292e-08,DB0078810027599_,18.25343666,1.457788883,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,33007,DB01373,10027599,126,22594,15,7366,4.73925762788187e-05,2.738584778,1.59729454,5.040776506,0.000422067,DB0137310027599_,7.770347356,1.007441283,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,calcium,DB01373
,33008,DB08895,10027599,188,27926,19,6627,0.000121006,2.348065294,1.460898174,3.990554214,0.000938656,DB0889510027599_,6.971061363,0.85359171,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,33009,DB00158,10061218,58,16757,17,8087,0.083120577,1.646502194,0.944799426,3.018202761,0.183637266,DB0015810061218_,1.694792847,0.498653156,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,33011,DB01373,10061218,64,22656,13,7368,0.14383743,1.600971843,0.872483597,3.170732773,0.275265151,DB0137310061218_,1.29002046,0.470610847,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,33012,DB08895,10061218,122,27992,29,6617,1,0.994463991,0.65824147,1.548302412,1,DB0889510061218_,0,-0.00555139,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,33018,DB08908,10047571,96,10577,25,3254,0.518777717,1.181354468,0.7527315,1.918673114,0.677989921,DB0890810047571_,0.388622857,0.166661635,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,dimethyl fumarate,DB08908
,33020,DB00635,10000084,37,33016,26,23768,1,1.024465033,0.603681661,1.762586918,1,DB0063510000084_,0,0.024170558,NA,10000084,Abdominal pain lower,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,33023,DB00087,10028813,87,1282,19,728,6.65245249973037e-05,2.599212083,1.553539102,4.561384136,0.000561889,DB0008710028813_,7.484207053,0.955208354,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,alemtuzumab,DB00087
,33024,DB00688,10028813,328,6162,128,5250,1.93375723384177e-14,2.183031119,1.76823641,2.70841124,1.093092664334e-12,DB0068810028813_,27.54201013,0.780714332,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,mycophenolate mofetil,DB00688
,33027,DB00635,10044439,100,32953,140,23654,3.517341681989e-07,0.512738803,0.39242227,0.66784792,5.63911717664415e-06,DB0063510044439_,12.08578303,-0.667988719,NA,10044439,Transplant rejection,10021428,Immune system disorders,Immun,prednisone,DB00635
,33028,DB00688,10044439,112,6378,125,5253,0.021089722,0.737981945,0.565144955,0.962710071,0.064477273,DB0068810044439_,2.741442479,-0.303835919,NA,10044439,Transplant rejection,10021428,Immune system disorders,Immun,mycophenolate mofetil,DB00688
,33030,DB00087,10047700,55,1314,10,737,0.000504333,3.083522043,1.544917799,6.827267747,0.003111462,DB0008710047700_,5.772662668,1.126072464,female,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,alemtuzumab,DB00087
,33031,DB00688,10047700,182,6308,84,5294,4.79906301532438e-06,1.818285969,1.392653443,2.39013731,5.70526329071919e-05,DB0068810047700_,9.771536332,0.597894282,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,mycophenolate mofetil,DB00688
,33035,DB00422,10008479,32,3403,28,2921,1,0.980982186,0.570624286,1.695313607,1,DB0042210008479_,0,-0.019200979,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,33036,DB00422,10053762,113,3322,118,2831,0.139197405,0.816116432,0.621727128,1.070854421,0.268683957,DB0042210053762_,1.314219471,-0.203198247,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,methylphenidate,DB00422
,33041,DB08868,10004146,64,9138,24,2487,0.19189919,0.725782581,0.44656905,1.216120394,0.339040175,DB0886810004146_,1.081636667,-0.320504784,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fingolimod,DB08868
,33044,DB08868,10040882,36,9166,15,2496,0.171615287,0.653572859,0.348343634,1.287025439,0.312923747,DB0886810040882_,1.161795739,-0.425301262,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,fingolimod,DB08868
,33059,DB00005,10008796,50,128032,18,42401,0.779178429,0.919922256,0.527369767,1.675618152,0.879672513,DB0000510008796_,0.128205585,-0.083466116,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,etanercept,DB00005
,33064,DB06403,10018092,57,21414,10,6651,0.112352966,1.77027747,0.895387007,3.890798281,0.229606416,DB0640310018092_,1.47138867,0.571136297,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,33065,DB06403,10018884,231,21240,52,6609,0.034938379,1.38222759,1.01785152,1.907908649,0.095304618,DB0640310018884_,2.350677007,0.323696394,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ambrisentan,DB06403
,33066,DB00820,10037423,178,11737,65,5751,0.045880566,1.341823684,1.002739691,1.814463458,0.117255292,DB0082010037423_,2.143401742,0.294029647,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,33067,DB06403,10037423,151,21320,39,6622,0.346224036,1.202569495,0.839813242,1.758978719,0.515623604,DB0640310037423_,0.66237823,0.184460514,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,33070,DB00153,10008190,53,7370,29,3410,0.475785915,0.845626355,0.526890167,1.382005232,0.641335014,DB0015310008190_,0.444203317,-0.167677678,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,33075,DB08899,10028411,6,243,113,8020,0.169559376,1.752275494,0.623571439,3.990078835,0.31034139,DB0889910028411_,1.170082328,0.560915226,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,enzalutamide,DB08899
,33081,DB00060,10010774,70,9438,15,2450,0.590711205,1.211394353,0.685274138,2.28281212,0.737267048,DB0006010010774_,0.304805108,0.191772054,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,interferon beta-1a,DB00060
,33087,DB01216,10033371,9,227,179,6936,0.20575685,1.536157278,0.682232324,3.034913289,0.356150196,DB0121610033371_,1.032402739,0.429284024,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,finasteride,DB01216
,33104,DB00169,10007554,89,38602,69,18106,0.002038238,0.604995993,0.4366214,0.841343435,0.009875593,DB0016910007554_,4.617688958,-0.502533444,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,33105,DB00175,10007554,24,8107,30,6076,0.072611235,0.599614376,0.33508603,1.062104043,0.16585586,DB0017510007554_,1.796636179,-0.511468536,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,pravastatin,DB00175
,33107,DB00281,10007554,30,11428,27,5644,0.024418201,0.548743689,0.314940145,0.960391564,0.072225435,DB0028110007554_,2.627963014,-0.600123816,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,lidocaine,DB00281
,33108,DB00316,10007554,164,65310,137,36816,0.000750104,0.674840056,0.534352446,0.853280265,0.004332815,DB0031610007554_,5.4415379,-0.39327957,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,33109,DB00421,10007554,142,8761,98,5154,0.226024688,0.852434563,0.652762021,1.116899153,0.380910362,DB0042110007554_,0.965191201,-0.159658831,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,spironolactone,DB00421
,33110,DB00588,10007554,57,16467,47,8421,0.016820029,0.620185951,0.413738216,0.933712952,0.053939422,DB0058810007554_,2.919893673,-0.477735924,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,fluticasone propionate,DB00588
,33111,DB00635,10007554,116,32937,108,23686,0.057363068,0.772410762,0.58883887,1.013890453,0.138468936,DB0063510007554_,1.97710927,-0.258238795,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,prednisone,DB00635
,33117,DB01222,10007554,39,9235,36,5369,0.054133621,0.62987248,0.389503073,1.02101111,0.132709665,DB0122210007554_,2.019591508,-0.462237893,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,budesonide,DB01222
,33119,DB06403,10007554,269,21202,105,6556,0.049839497,0.792189274,0.628825338,1.004091652,0.124735175,DB0640310007554_,2.081562387,-0.232954933,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,ambrisentan,DB06403
,33144,DB00115,10013036,50,18375,13,10459,0.008655631,2.189165387,1.170926712,4.395192061,0.031726853,DB0011510013036_,3.450591866,0.783520369,NA,10013036,Diplopia,10015919,Eye disorders,Eye,cyanocobalamin,DB00115
,33145,DB00169,10013036,68,38623,24,18151,0.263312738,1.331576436,0.824880465,2.2187399,0.425120562,DB0016910013036_,0.855382474,0.28636353,NA,10013036,Diplopia,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,33149,DB00281,10013036,45,11413,10,5661,0.020759885,2.231970357,1.107854993,4.97120121,0.06365396,DB0028110013036_,2.754293739,0.802884763,NA,10013036,Diplopia,10015919,Eye disorders,Eye,lidocaine,DB00281
,33150,DB00316,10013036,84,65390,30,36923,0.031589961,1.58103579,1.030684158,2.486166459,0.088213578,DB0031610013036_,2.427994381,0.458080196,NA,10013036,Diplopia,10015919,Eye disorders,Eye,acetaminophen,DB00316
,33154,DB00635,10013036,35,33018,33,23761,0.270632053,0.763264205,0.460529668,1.267577685,0.433317912,DB0063510013036_,0.836283612,-0.270151036,NA,10013036,Diplopia,10015919,Eye disorders,Eye,prednisone,DB00635
,33156,DB00695,10013036,40,28009,16,20512,0.0420429,1.830809631,1.002310437,3.502945689,0.109796089,DB0069510013036_,2.209130373,0.60475829,NA,10013036,Diplopia,10015919,Eye disorders,Eye,furosemide,DB00695
,33165,DB00091,10013573,157,5353,26,2644,1.44122615350979e-08,2.982249394,1.954636864,4.719890342,3.1230527159938e-07,DB0009110013573_,14.97928469,1.092677846,female,10013573,Dizziness,10029205,Nervous system disorders,Nerv,cyclosporine,DB00091
,33166,DB00181,10013573,309,9547,135,5736,0.002022326,1.37517643,1.116708632,1.700712893,0.009813206,DB0018110013573_,4.624026226,0.318582036,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,33167,DB00281,10013573,274,11184,122,5549,0.358407316,1.114303554,0.89471238,1.394353633,0.528142189,DB0028110013573_,0.638389734,0.108229594,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,33168,DB00710,10013573,66,2340,6,195,0.82149536,0.916725192,0.392408201,2.621025586,0.904892846,DB0071010013573_,0.099938745,-0.086947533,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ibandronate,DB00710
,33169,DB00829,10013573,263,7789,88,4366,2.08749284211249e-05,1.675167817,1.307144418,2.163780945,0.000207207,DB0082910013573_,8.481792266,0.51591335,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,33170,DB00874,10013573,90,3245,44,1932,0.319753762,1.217736829,0.836012352,1.796706876,0.487881096,DB0087410013573_,0.71768356,0.196994078,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,guaifenesin,DB00874
,33171,DB01222,10013573,257,9017,126,5279,0.107682588,1.194160706,0.958427709,1.493920345,0.222683772,DB0122210013573_,1.502002576,0.1774436,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,33172,DB05351,10013573,97,2626,31,1100,0.235831408,1.310583812,0.860719078,2.045384655,0.392972898,DB0535110013573_,0.934014632,0.270472696,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,dexlansoprazole,DB05351
,33173,DB00710,10013968,69,2337,8,193,0.381274834,0.712401463,0.33546767,1.740972626,0.551300108,DB0071010013968_,0.595475958,-0.339113675,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibandronate,DB00710
,33174,DB00829,10013968,218,7834,95,4359,0.048736863,1.276833594,0.99589788,1.647160276,0.122682287,DB0082910013968_,2.0981573,0.244383258,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diazepam,DB00829
,33175,DB00874,10013968,205,3130,157,1819,0.013152066,0.758884795,0.608338291,0.947994581,0.044303737,DB0087410013968_,3.116686259,-0.275905298,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,guaifenesin,DB00874
,33176,DB05351,10013968,130,2593,36,1095,0.029077918,1.524785884,1.039100159,2.287319249,0.082677599,DB0535110013968_,2.492806584,0.421853996,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexlansoprazole,DB05351
,33178,DB00115,10014020,54,18371,8,10464,5.42111558269622e-05,3.84461352,1.817576346,9.357679539,0.000472852,DB0011510014020_,7.656727603,1.346673083,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,cyanocobalamin,DB00115
,33179,DB00169,10014020,114,38577,9,18166,8.02357574722121e-11,5.964961113,3.033093357,13.37886582,2.65885131312588e-09,DB0016910014020_,19.74537164,1.785902536,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,cholecalciferol,DB00169
,33184,DB00316,10014020,128,65346,23,36930,1.98729446743111e-08,3.145120711,2.00634572,5.14005165,4.16223387063161e-07,DB0031610014020_,14.69204373,1.145852271,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,acetaminophen,DB00316
,33187,DB00635,10014020,79,32974,16,23778,3.15429230462273e-07,3.560394216,2.06191667,6.531153644,5.11320217249513e-06,DB0063510014020_,12.1836847,1.269871274,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,prednisone,DB00635
,33189,DB00695,10014020,60,27989,13,20515,1.32585563740963e-05,3.382805162,1.835811135,6.719753733,0.000139122,DB0069510014020_,8.88015775,1.218705295,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,furosemide,DB00695
,33200,DB00203,10015967,52,13826,11,8927,0.000252953,3.052100654,1.572203769,6.490297157,0.001753164,DB0020310015967_,6.346333293,1.115830093,female,10015967,Eye swelling,10015919,Eye disorders,Eye,sildenafil,DB00203
,33205,DB00635,10015967,84,32969,20,23774,1.22700552764758e-06,3.028528695,1.842075548,5.210287025,1.71826533267003e-05,DB0063510015967_,10.97161021,1.108076922,female,10015967,Eye swelling,10015919,Eye disorders,Eye,prednisone,DB00635
,33206,DB00682,10015967,49,19410,19,16345,0.003270456,2.1716162,1.25489362,3.907883696,0.014512186,DB0068210015967_,4.232766547,0.775471683,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,warfarin,DB00682
,33207,DB00695,10015967,78,27971,23,20505,4.71414033013199e-05,2.486028436,1.544007457,4.150270001,0.000420252,DB0069510015967_,7.774657024,0.910686431,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,furosemide,DB00695
,33215,DB06403,10015967,72,21399,22,6639,1,1.015360135,0.621893426,1.720900552,1,DB0640310015967_,0,0.015243363,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,ambrisentan,DB06403
,33217,DB00115,10016807,128,18297,53,10419,0.052547276,1.375230961,0.990093786,1.933587412,0.129794217,DB0011510016807_,2.041805032,0.318621689,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,cyanocobalamin,DB00115
,33218,DB00169,10016807,234,38457,88,18087,0.082043478,1.250580995,0.974051234,1.617865404,0.181783337,DB0016910016807_,1.704939757,0.22360824,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,33219,DB00175,10016807,60,8071,33,6073,0.17164922,1.368054801,0.87896475,2.163090089,0.312960826,DB0017510016807_,1.161677252,0.313389878,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,pravastatin,DB00175
,33221,DB00281,10016807,41,11417,28,5643,0.200324027,0.723731462,0.43635215,1.216580026,0.349403919,DB0028110016807_,1.051526665,-0.323334864,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,lidocaine,DB00281
,33222,DB00635,10016807,221,32832,110,23684,0.001418462,1.449286037,1.147098718,1.839914859,0.007337981,DB0063510016807_,4.914691552,0.371071047,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,33226,DB00950,10016807,38,4680,16,2040,1,1.035220173,0.562152898,1.993477653,1,DB0095010016807_,0,0.034614131,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,fexofenadine,DB00950
,33227,DB01136,10016807,136,9748,99,11016,0.000980479,1.552382723,1.18768258,2.035073411,0.00541654,DB0113610016807_,5.218297982,0.439790991,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,carvedilol,DB01136
,33228,DB01175,10016807,66,10658,10,4882,0.000427047,3.022987885,1.543131139,6.599909275,0.002706759,DB0117510016807_,5.912003128,1.106245708,female,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,escitalopram,DB01175
,33229,DB01222,10016807,95,9179,27,5378,0.000632174,2.061415749,1.330340465,3.293306524,0.003763262,DB0122210016807_,5.58246926,0.723393004,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,budesonide,DB01222
,33255,DB00115,10033318,67,18358,27,10445,0.133862577,1.411851897,0.890158279,2.298049368,0.261138329,DB0011510033318_,1.342705015,0.344902245,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,33256,DB00175,10033318,46,8085,23,6083,0.114169654,1.504718274,0.892393973,2.603951778,0.232370541,DB0017510033318_,1.45942202,0.408605688,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,pravastatin,DB00175
,33257,DB00181,10033318,32,9824,18,5853,0.884759525,1.059176414,0.576282938,2.005933657,0.95196507,DB0018110033318_,0.049226936,0.057491639,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,baclofen,DB00181
,33258,DB00281,10033318,38,11420,43,5628,0.000211599,0.435532776,0.273633529,0.690873779,0.001510357,DB0028110033318_,6.495409073,-0.831185226,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,lidocaine,DB00281
,33259,DB00316,10033318,247,65227,112,36841,0.054134032,1.245648894,0.992021259,1.572099238,0.132709665,DB0031610033318_,2.019591508,0.219656594,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,33260,DB00588,10033318,148,16376,62,8406,0.188181884,1.225282994,0.903855733,1.678083357,0.334292624,DB0058810033318_,1.095738548,0.203171833,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,33261,DB00635,10033318,209,32844,89,23705,2.08671258423272e-05,1.694864641,1.315552627,2.198549828,0.000207174,DB0063510033318_,8.481952928,0.52760288,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,prednisone,DB00635
,33262,DB00682,10033318,380,19079,125,16239,1.52622169770211e-22,2.58731607,2.106181718,3.196409862,2.005836866205e-20,DB0068210033318_,45.3556405,0.950621072,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,warfarin,DB00682
,33267,DB01136,10033318,64,9820,45,11070,0.016003285,1.603206786,1.076874339,2.404899519,0.051835657,DB0113610033318_,2.959677014,0.472005865,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,carvedilol,DB01136
,33269,DB01222,10033318,94,9180,51,5354,0.729587001,1.074965454,0.755175568,1.545405373,0.842472184,DB0122210033318_,0.171414633,0.072288526,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,budesonide,DB01222
,33273,DB00203,10033433,747,13131,233,8705,2.66963332587048e-25,2.12529733,1.827493379,2.47915293,4.15214863730802e-23,DB0020310033433_,51.53583119,0.753911713,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,33275,DB00316,10033433,181,65293,56,36897,4.46147868273038e-05,1.826468938,1.346202652,2.511677695,0.000401032,DB0031610033433_,7.821469237,0.602384561,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,33276,DB00559,10033433,163,9496,49,3257,0.474601851,1.140941436,0.822169778,1.608201714,0.640280733,DB0055910033433_,0.445848553,0.131853743,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,bosentan,DB00559
,33277,DB00588,10033433,75,16449,21,8447,0.012678903,1.83398339,1.117123601,3.136133723,0.043008459,DB0058810033433_,3.146358454,0.606490317,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,33278,DB00635,10033433,122,32931,33,23761,7.85877038275338e-08,2.667436089,1.802260728,4.048414236,1.45521507228371e-06,DB0063510033433_,13.44035685,0.981117745,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,33279,DB00695,10033433,270,27779,60,20468,1.21145734008127e-20,3.315547834,2.496752309,4.464799002,1.35502792272494e-18,DB0069510033433_,41.14270961,1.198622869,female,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,33285,DB01222,10033433,37,9237,14,5391,0.191310724,1.542410344,0.813571142,3.091572714,0.338205091,DB0122210033433_,1.08410279,0.433346351,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,budesonide,DB01222
,33287,DB06403,10033433,774,20697,177,6484,0.000140704,1.369908208,1.15914727,1.626105987,0.001067517,DB0640310033433_,6.842419801,0.314743736,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,33289,DB00203,10037377,68,13810,57,8881,0.142506421,0.767209909,0.531036861,1.111911677,0.273314942,DB0020310037377_,1.297130513,-0.264994839,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,33290,DB00281,10037377,70,11388,39,5632,0.541833564,0.88767534,0.590865567,1.350849897,0.697150876,DB0028110037377_,0.360753427,-0.119149211,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,33291,DB00559,10037377,68,9591,16,3290,0.208804396,1.457801049,0.835061959,2.697189015,0.359869729,DB0055910037377_,1.022013176,0.376929169,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,33293,DB00829,10037377,36,8016,20,4434,1,0.995658513,0.560393324,1.81755442,1,DB0082910037377_,0,-0.004350938,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diazepam,DB00829
,33294,DB00874,10037377,37,3298,21,1955,1,1.04442284,0.59360839,1.883762223,1,DB0087410037377_,0,0.043464427,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,guaifenesin,DB00874
,33296,DB01136,10037377,59,9825,73,11042,0.600765279,0.908358428,0.632642439,1.299457688,0.745127538,DB0113610037377_,0.294199883,-0.096116233,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,33297,DB01175,10037377,83,10641,35,4857,0.765308627,1.082412876,0.719798268,1.658618576,0.870521783,DB0117510037377_,0.138662497,0.079192694,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,33299,DB06403,10037377,53,21418,22,6639,0.275708611,0.746761477,0.446068979,1.290438658,0.438972733,DB0640310037377_,0.823317981,-0.292009453,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,33301,DB00115,10051055,129,18296,118,10354,0.000240213,0.618651898,0.477667899,0.801991197,0.001678808,DB0011510051055_,6.389671047,-0.480212526,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,cyanocobalamin,DB00115
,33302,DB00169,10051055,233,38458,209,17966,1.8751301293148e-11,0.520789073,0.429861288,0.631324368,6.83603265590007e-10,DB0016910051055_,21.10364339,-0.652410169,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,33307,DB00950,10051055,30,4688,22,2034,0.068905791,0.591695893,0.329157456,1.079363893,0.159351462,DB0095010051055_,1.836643065,-0.52476247,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,fexofenadine,DB00950
,33308,DB01136,10051055,57,9827,79,11036,0.262512284,0.810295283,0.56537479,1.15499635,0.424297334,DB0113610051055_,0.85732081,-0.210356551,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,carvedilol,DB01136
,33309,DB01222,10051055,46,9228,31,5374,0.554453872,0.864158,0.535594164,1.411662105,0.707965317,DB0122210051055_,0.345360173,-0.145999656,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,budesonide,DB01222
,33313,DB01050,10028334,258,17850,128,9243,0.745663782,1.0437216,0.83986142,1.302355926,0.85479359,DB0105010028334_,0.156895254,0.042792787,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,33315,DB01050,10033664,36,18072,14,9357,0.455488134,1.331399354,0.700347317,2.673617277,0.622923907,DB0105010033664_,0.473330907,0.286230535,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,33317,DB00635,10002855,459,32594,155,23639,8.03571734424413e-18,2.147648194,1.784867639,2.595720548,6.75900257259062e-16,DB0063510002855_,34.93048616,0.76437338,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,33318,DB00758,10002855,88,8212,54,10020,6.16519563706707e-05,1.988317931,1.399234718,2.848167055,0.000527857,DB0075810002855_,7.546684723,0.68728902,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,clopidogrel,DB00758
,33319,DB01190,10002855,55,4879,15,2270,0.070612958,1.705837523,0.947686111,3.258448054,0.162385092,DB0119010002855_,1.817784655,0.534056206,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,clindamycin,DB01190
,33320,DB01377,10002855,53,3743,23,2647,0.060132062,1.629484359,0.978728881,2.793050801,0.143723501,DB0137710002855_,1.939863955,0.488263621,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,magnesium oxide,DB01377
,33331,DB00635,10008190,194,32859,163,23631,0.146513512,0.855942461,0.690921078,1.061419316,0.279045552,DB0063510008190_,1.27638024,-0.155552124,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,33332,DB00758,10008190,248,8052,243,9831,0.016821986,1.246040103,1.037148139,1.497171831,0.053942406,DB0075810008190_,2.919838362,0.219970606,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,33336,DB00736,10012378,171,10420,62,5491,0.012243578,1.45337825,1.0787259,1.979998161,0.041824999,DB0073610012378_,3.174261064,0.373890674,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,esomeprazole,DB00736
,33337,DB00758,10012378,85,8215,64,10010,0.003750761,1.618258955,1.154619861,2.277792399,0.01619528,DB0075810012378_,4.123035463,0.481350852,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,clopidogrel,DB00758
,33338,DB01190,10012378,57,4877,22,2263,0.543425193,1.202172449,0.72140213,2.070678676,0.698629381,DB0119010012378_,0.358634891,0.184130294,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,clindamycin,DB01190
,33339,DB01377,10012378,70,3726,17,2653,2.29544656547693e-05,2.931394071,1.702179028,5.326687822,0.000224631,DB0137710012378_,8.401052722,1.075478102,female,10012378,Depression,10037175,Psychiatric disorders,Psych,magnesium oxide,DB01377
,33341,DB00635,10022116,89,32964,22,23772,1.04504025737677e-06,2.917284025,1.812494179,4.888508939,1.48761890956666e-05,DB0063510022116_,11.11574867,1.070653055,female,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,33345,DB00338,10027374,47,33627,15,22257,0.013104823,2.073854356,1.139069727,3.994166068,0.044170066,DB0033810027374_,3.119707954,0.729408884,NA,10027374,Mental impairment,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,33355,DB00758,10033371,304,7996,193,9881,4.79254220826641e-13,1.946355669,1.615697845,2.349199301,2.23751282316665e-11,DB0075810033371_,24.52307112,0.665958736,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,33356,DB01377,10033371,129,3667,59,2611,0.005310196,1.556699298,1.130417094,2.165035534,0.021464155,DB0137710033371_,3.84137096,0.442567745,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,33358,DB00338,10033775,392,33282,151,22121,5.1287336296065e-09,1.72543887,1.425375827,2.097529101,1.22832586290849e-07,DB0033810033775_,15.9124435,0.545481436,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,33359,DB00635,10033775,285,32768,116,23678,8.38072425258341e-08,1.775317465,1.424735027,2.224048124,1.54100970254743e-06,DB0063510033775_,13.38307271,0.57397926,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,33360,DB00736,10033775,129,10462,52,5501,0.115569871,1.304413421,0.936686736,1.839431707,0.234548436,DB0073610033775_,1.450093164,0.265753454,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,33361,DB00758,10033775,77,8223,49,10025,0.000416447,1.915699908,1.320181651,2.803132741,0.002649153,DB0075810033775_,5.933515464,0.650083043,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,33362,DB00916,10033775,55,5268,26,2405,0.90433895,0.96576047,0.593710868,1.60858863,0.957497529,DB0091610033775_,0.043432138,-0.034839436,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,metronidazole,DB00916
,33364,DB01377,10033775,46,3750,16,2654,0.013437417,2.034516739,1.12766821,3.858771871,0.045042721,DB0137710033775_,3.100143889,0.710258316,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,magnesium oxide,DB01377
,33367,DB00722,10037377,143,25260,197,25835,0.00757802,0.7424186,0.59395485,0.926144296,0.028524739,DB0072210037377_,3.556983532,-0.297842044,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,33368,DB00758,10037377,46,8254,56,10018,1,0.99697994,0.659238165,1.501119,1,DB0075810037377_,0,-0.003024629,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,33371,DB01377,10037377,40,3756,34,2636,0.409165216,0.825689112,0.508083263,1.34876207,0.578578567,DB0137710037377_,0.54718093,-0.191536954,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium oxide,DB01377
,33373,DB00635,10041466,69,32984,32,23762,0.04310638,1.553369764,1.007142242,2.442728663,0.111895241,DB0063510041466_,2.190192194,0.440426612,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,33374,DB00722,10041466,80,25323,75,25957,0.629463697,1.093355348,0.787478948,1.519544923,0.768501511,DB0072210041466_,0.26331275,0.089251269,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,33376,DB00758,10041466,33,8267,27,10047,0.152469548,1.485334289,0.865309002,2.57036701,0.287421528,DB0075810041466_,1.246805403,0.395639857,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,33382,DB00338,10049119,66,33608,12,22260,4.0538538497342e-06,3.642794567,1.951584846,7.406761356,4.91492382104536e-05,DB0033810049119_,9.920649211,1.292751125,female,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,33383,DB00635,10049119,49,33004,14,23780,0.00129779,2.521752178,1.369692039,4.947287227,0.006817651,DB0063510049119_,4.988240234,0.924953969,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,33389,DB00758,10051055,37,8263,60,10014,0.183705847,0.747356285,0.481709497,1.145702743,0.328579036,DB0075810051055_,1.112977873,-0.291213253,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,clopidogrel,DB00758
,33390,DB00916,10051055,35,5288,17,2414,0.880936521,0.939872572,0.51143063,1.792744873,0.950123172,DB0091610051055_,0.051163648,-0.062010975,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,metronidazole,DB00916
,33392,DB01377,10051055,30,3766,39,2631,0.013375086,0.537465828,0.321549975,0.890275332,0.044893899,DB0137710051055_,3.103453373,-0.620890097,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,magnesium oxide,DB01377
,33395,DB00341,10000059,183,11222,44,5024,0.000116554,1.861930145,1.330955206,2.65464925,0.000909762,DB0034110000059_,7.002327396,0.621613662,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,33396,DB00448,10000059,76,5069,28,3096,0.024698427,1.657712406,1.059238488,2.662595007,0.072845396,DB0044810000059_,2.619415951,0.505438583,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,lansoprazole,DB00448
,33397,DB00524,10000059,35,1542,15,1329,0.02230044,2.010524965,1.064403839,3.980904318,0.067294307,DB0052410000059_,2.698679633,0.698395865,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,metolazone,DB00524
,33398,DB00820,10000059,287,11628,114,5702,0.059835172,1.23447447,0.987896245,1.551171295,0.143180618,DB0082010000059_,1.943648381,0.21064535,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,33399,DB00836,10000059,107,5428,31,4044,8.99740753090583e-07,2.571276717,1.706002318,3.977805528,1.3055305379512e-05,DB0083610000059_,11.24631596,0.944402552,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,33402,DB01240,10000059,177,5574,60,1516,0.148401017,0.802357897,0.591961273,1.100279528,0.281788048,DB0124010000059_,1.266600095,-0.220200515,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,33403,DB01373,10000059,271,22449,73,7308,0.165499325,1.208491071,0.928694505,1.589472845,0.304792417,DB0137310000059_,1.188124335,0.189372532,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,33404,DB06228,10000059,156,15756,81,15995,6.04571920002879e-07,1.955087798,1.484015647,2.592016683,9.16974778838758e-06,DB0622810000059_,11.59960078,0.670435102,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,33405,DB06403,10000059,351,21120,110,6551,0.912115001,0.989756078,0.79524394,1.239837504,0.960588545,DB0640310000059_,0.040209114,-0.010296752,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,33406,DB09140,10000059,106,3635,30,1768,0.009164406,1.718399461,1.131309487,2.681614766,0.033198238,DB0914010000059_,3.405258484,0.541393312,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,oxygen,DB09140
,33407,DB14500,10000059,125,7684,38,4035,0.002695161,1.727286318,1.190165062,2.558706192,0.012387187,DB1450010000059_,4.391092686,0.546551575,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,33408,DB00126,10000081,177,9994,74,5871,0.014612087,1.405094315,1.063161006,1.872594024,0.048284455,DB0012610000081_,3.030645622,0.340104428,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,33409,DB00211,10000081,35,1401,16,1615,0.001736869,2.52091016,1.352162425,4.900078452,0.008653071,DB0021110000081_,4.749841015,0.924620011,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,midodrine,DB00211
,33410,DB00374,10000081,357,17359,97,5627,0.136287573,1.193009348,0.948616771,1.512175286,0.264514425,DB0037410000081_,1.329859493,0.176478979,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,33411,DB00448,10000081,106,5039,45,3079,0.042171987,1.439263655,1.003268619,2.09414154,0.110023888,DB0044810000081_,2.207057775,0.364131632,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,lansoprazole,DB00448
,33412,DB00524,10000081,49,1528,16,1328,0.000384064,2.660707061,1.479126053,5.037107387,0.002479461,DB0052410000081_,5.999714014,0.9785919,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,metolazone,DB00524
,33413,DB00559,10000081,143,9516,33,3273,0.044725748,1.490348347,1.012452452,2.252379735,0.115053463,DB0055910000081_,2.162358363,0.399009883,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,33417,DB06228,10000081,135,15777,90,15986,0.002055641,1.519842121,1.154316448,2.009068353,0.009946524,DB0622810000081_,4.610532121,0.418606462,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,33418,DB06403,10000081,302,21169,70,6591,0.026954824,1.343231307,1.030964144,1.770719678,0.077922193,DB0640310000081_,2.55204447,0.295078135,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,33419,DB09140,10000081,106,3635,24,1774,0.000413396,2.155222576,1.367814529,3.524323195,0.002632834,DB0914010000081_,5.939694462,0.767894002,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,oxygen,DB09140
,33420,DB14500,10000081,142,7667,35,4038,2.86888465570048e-05,2.136666592,1.463971952,3.194904378,0.000272824,DB1450010000081_,8.206682604,0.759246947,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,33421,DB00126,10001053,43,10128,24,5921,0.899685674,1.047439049,0.620806978,1.806412388,0.956571579,DB0012610001053_,0.044399659,0.046348184,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,33422,DB00169,10001053,110,38581,93,18082,4.13936408899229e-05,0.554384663,0.41652179,0.739097742,0.000375637,DB0016910001053_,7.886887968,-0.589896495,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,33423,DB00175,10001053,35,8096,37,6069,0.152986616,0.709136183,0.433106428,1.158903389,0.288158595,DB0017510001053_,1.244244272,-0.343707693,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,33425,DB00341,10001053,41,11364,24,5044,0.283325195,0.758248432,0.446866867,1.313498968,0.447689177,DB0034110001053_,0.803656088,-0.276744201,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,33426,DB00374,10001053,157,17559,70,5654,0.029384528,0.722211296,0.540651945,0.973055457,0.083337539,DB0037410001053_,2.484856186,-0.325437529,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,33428,DB00451,10001053,144,47127,79,15340,0.000314036,0.593328965,0.447572448,0.791421914,0.002095564,DB0045110001053_,6.16793234,-0.522006288,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,33429,DB00524,10001053,44,1533,27,1317,0.186054593,1.399853146,0.842465983,2.365094182,0.331555591,DB0052410001053_,1.103959789,0.336367336,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metolazone,DB00524
,33430,DB00559,10001053,95,9564,41,3265,0.234834372,0.791021278,0.541696016,1.173161458,0.391763231,DB0055910001053_,0.937097624,-0.234430411,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,33431,DB00820,10001053,95,11820,52,5764,0.53699358,0.890906222,0.627798983,1.276530531,0.69321397,DB0082010001053_,0.366416568,-0.115516107,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,33435,DB00996,10001053,131,38822,101,22324,0.028770761,0.745860942,0.570638519,0.977205788,0.08196829,DB0099610001053_,2.501422819,-0.293216101,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,33436,DB01240,10001053,61,5690,30,1546,0.010013524,0.552522751,0.349921234,0.889567972,0.035604392,DB0124010001053_,3.335286278,-0.593260669,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,33437,DB01373,10001053,50,22670,8,7373,0.065764457,2.032543626,0.955569024,4.96640591,0.153750667,DB0137310001053_,1.872423034,0.709288026,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,33439,DB06228,10001053,48,15864,52,16024,0.764296712,0.932359609,0.616070831,1.40854922,0.869789975,DB0622810001053_,0.139503504,-0.070036692,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,33440,DB06403,10001053,146,21325,64,6597,0.022473519,0.705726396,0.521850812,0.963526405,0.067661239,DB0640310001053_,2.6932418,-0.348527658,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,33441,DB09140,10001053,108,3633,63,1735,0.214292743,0.8187337,0.591230923,1.141804734,0.366639637,DB0914010001053_,1.003375829,-0.199996401,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,33444,DB00211,10005734,35,1401,55,1576,0.134166404,0.71593102,0.451839847,1.12109875,0.261536927,DB0021110005734_,1.341179793,-0.334171457,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,midodrine,DB00211
,33446,DB00374,10005734,281,17435,75,5649,0.152617971,1.213917505,0.93603631,1.590752492,0.287608501,DB0037410005734_,1.246155097,0.193852737,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,treprostinil,DB00374
,33448,DB00451,10005734,182,47089,80,15339,0.030738609,0.741073551,0.566321624,0.977066813,0.086357881,DB0045110005734_,2.449255212,-0.299655399,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,33450,DB00559,10005734,54,9605,16,3290,0.681503698,1.156023159,0.650736566,2.167089983,0.807434868,DB0055910005734_,0.213892886,0.144985804,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,bosentan,DB00559
,33451,DB00695,10005734,164,27885,136,20392,0.291486081,0.881852767,0.697733873,1.116051851,0.456948793,DB0069510005734_,0.783183944,-0.125730168,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,furosemide,DB00695
,33452,DB00820,10005734,134,11781,52,5764,0.181768094,1.260734624,0.907352007,1.774759847,0.326151169,DB0082010005734_,1.120394295,0.231694586,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,tadalafil,DB00820
,33456,DB00996,10005734,112,38841,73,22352,0.40163694,0.882925012,0.651341543,1.203084538,0.571406834,DB0099610005734_,0.559653829,-0.124515006,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,gabapentin,DB00996
,33457,DB01240,10005734,69,5682,20,1556,0.795948117,0.944774075,0.565359722,1.646595632,0.88948158,DB0124010005734_,0.11711648,-0.056809454,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,epoprostenol,DB01240
,33458,DB01373,10005734,78,22642,23,7358,0.729680071,1.102072342,0.68416707,1.840422212,0.84254264,DB0137310005734_,0.171331006,0.097192355,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,calcium,DB01373
,33460,DB09140,10005734,66,3675,22,1776,0.137432208,1.44970525,0.879662006,2.475736001,0.266136634,DB0914010005734_,1.323745442,0.37136026,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,oxygen,DB09140
,33461,DB14500,10005734,40,7769,17,4056,0.576144587,1.228355434,0.679771413,2.31388462,0.725459184,DB1450010005734_,0.320950468,0.20567623,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,potassium,DB14500
,33462,DB00126,10007515,23,10148,44,5901,2.55140897520528e-06,0.303986054,0.175022341,0.515028872,3.27779984913347e-05,DB0012610007515_,10.32575305,-1.190773452,male,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,ascorbic acid,DB00126
,33463,DB00175,10007515,24,8107,49,6057,4.03393816517876e-05,0.365966879,0.214483807,0.60883425,0.000367338,DB0017510007515_,7.909228615,-1.005212443,male,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,pravastatin,DB00175
,33465,DB00341,10007515,37,11368,29,5039,0.023138552,0.565585501,0.338051215,0.954609739,0.069239822,DB0034110007515_,2.670179126,-0.5698938,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,cetirizine,DB00341
,33467,DB00524,10007515,41,1536,18,1326,0.017223256,1.9658893,1.098280806,3.654085295,0.054953385,DB0052410007515_,2.901269999,0.675944713,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,metolazone,DB00524
,33468,DB00695,10007515,250,27799,239,20289,0.003206345,0.763449969,0.636214957,0.916285928,0.014280907,DB0069510007515_,4.248831827,-0.269907685,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,furosemide,DB00695
,33469,DB00820,10007515,93,11822,52,5764,0.425421181,0.872006417,0.613561114,1.250965813,0.594165555,DB0082010007515_,0.520597286,-0.136958497,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,tadalafil,DB00820
,33472,DB00996,10007515,342,38611,250,22175,0.004606242,0.785685249,0.664899612,0.92936291,0.019139278,DB0099610007515_,3.956012597,-0.241199014,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,gabapentin,DB00996
,33473,DB01240,10007515,71,5680,29,1547,0.085028258,0.666851851,0.425568971,1.069643761,0.186815543,DB0124010007515_,1.67763355,-0.40518737,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,epoprostenol,DB01240
,33474,DB01373,10007515,57,22663,43,7338,5.6592279382485e-05,0.429218118,0.28358983,0.653897345,0.000490852,DB0137310007515_,7.619367177,-0.845790055,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,calcium,DB01373
,33476,DB06228,10007515,71,15841,67,16009,0.733134325,1.07097188,0.755500271,1.51950199,0.845157481,DB0622810007515_,0.168232301,0.068566535,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,33477,DB09140,10007515,53,3688,30,1768,0.479632027,0.846964842,0.529257621,1.378202499,0.644575927,DB0914010007515_,0.439162655,-0.166096094,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,oxygen,DB09140
,33478,DB14500,10007515,33,7776,23,4050,0.323112008,0.747328559,0.425095469,1.33482626,0.491507227,DB1450010007515_,0.710278636,-0.291250353,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,potassium,DB14500
,33483,DB00374,10012442,230,17486,56,5668,0.061225247,1.331278843,0.988584552,1.819187562,0.145684661,DB0037410012442_,1.92631085,0.286140016,NA,10012442,Dermatitis contact,10040785,Skin and subcutaneous tissue disorders,Skin,treprostinil,DB00374
,33489,DB00820,10012442,117,11798,21,5795,3.9844461020937e-06,2.73647285,1.707600354,4.590910691,4.84417973143076e-05,DB0082010012442_,9.935147536,1.00666981,female,10012442,Dermatitis contact,10040785,Skin and subcutaneous tissue disorders,Skin,tadalafil,DB00820
,33494,DB01240,10012442,108,5643,16,1560,0.019996751,1.865840858,1.094367625,3.391099447,0.061753463,DB0124010012442_,2.78460523,0.623711813,NA,10012442,Dermatitis contact,10040785,Skin and subcutaneous tissue disorders,Skin,epoprostenol,DB01240
,33498,DB06403,10012442,93,21378,22,6639,0.273172332,1.312769227,0.81716633,2.196827756,0.436140474,DB0640310012442_,0.829790899,0.27213882,NA,10012442,Dermatitis contact,10040785,Skin and subcutaneous tissue disorders,Skin,ambrisentan,DB06403
,33501,DB00211,10012735,96,1340,64,1567,0.000617875,1.753759541,1.253745973,2.46677442,0.003690264,DB0021110012735_,5.602057255,0.561761793,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,midodrine,DB00211
,33502,DB00524,10012735,136,1441,64,1280,3.53434452043042e-05,1.887174817,1.377913888,2.607010615,0.00032769,DB0052410012735_,8.023441111,0.635080905,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,metolazone,DB00524
,33503,DB00930,10012735,92,1198,40,602,0.503389158,1.155699302,0.777986229,1.742709468,0.6645197,DB0093010012735_,0.408690754,0.144705617,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,colesevelam,DB00930
,33504,DB00972,10012735,109,2395,54,1125,0.796749862,0.948170364,0.672564576,1.350000131,0.889999156,DB0097210012735_,0.116534765,-0.053221084,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,azelastine,DB00972
,33506,DB14500,10012735,624,7185,228,3845,1.28280368135534e-06,1.464556052,1.249872069,1.720648262,1.78735726289028e-05,DB1450010012735_,10.93218733,0.38155216,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,33507,DB00126,10013573,366,9805,179,5766,0.046972219,1.202363786,0.999722281,1.450305537,0.119395105,DB0012610013573_,2.125317075,0.184289441,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,33508,DB00211,10013573,136,1300,142,1489,0.488283265,1.096954303,0.850303215,1.414735553,0.651862747,DB0021110013573_,0.42792125,0.092537524,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,midodrine,DB00211
,33510,DB00972,10013573,77,2427,24,1155,0.083099067,1.526671626,0.948829117,2.539070811,0.183612894,DB0097210013573_,1.694925576,0.423089958,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,azelastine,DB00972
,33512,DB00126,10013781,75,10096,19,5926,0.000557239,2.316858411,1.384151402,4.06442628,0.003375911,DB0012610013781_,5.691089992,0.840212135,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,33513,DB00169,10013781,284,38407,64,18111,1.70766438718911e-08,2.092499845,1.58950045,2.790737288,3.63155003375936e-07,DB0016910013781_,14.82843609,0.738359449,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,33514,DB00175,10013781,57,8074,23,6083,0.012234219,1.86704755,1.130717426,3.178837621,0.041801176,DB0017510013781_,3.174830798,0.624358333,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,33515,DB00341,10013781,62,11343,13,5055,0.011624563,2.125322001,1.155222511,4.217283874,0.040146056,DB0034110013781_,3.215231085,0.753923321,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,33516,DB00374,10013781,94,17622,23,5701,0.280190021,1.322167699,0.830042984,2.188739717,0.444015751,DB0037410013781_,0.811895241,0.279272586,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,33518,DB00451,10013781,339,46932,71,15348,0.000436245,1.561379214,1.204946538,2.0476347,0.002756071,DB0045110013781_,5.893949137,0.445569542,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,33520,DB00695,10013781,149,27900,65,20463,0.000385862,1.681249557,1.247437386,2.287385746,0.002489236,DB0069510013781_,5.995779318,0.519537301,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,33521,DB00820,10013781,67,11848,25,5791,0.267368916,1.309941442,0.815366914,2.167142662,0.42963729,DB0082010013781_,0.844813938,0.269982435,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,33525,DB00996,10013781,228,38725,84,22341,0.000388432,1.565898457,1.213495868,2.037026538,0.002504187,DB0099610013781_,5.989791188,0.448459753,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,33527,DB01373,10013781,156,22564,24,7357,0.000246555,2.119148975,1.371981377,3.409879696,0.001714925,DB0137310013781_,6.368385808,0.751014581,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,33529,DB06228,10013781,40,15872,23,16053,0.03185179,1.758921147,1.027360508,3.079335047,0.088783065,DB0622810013781_,2.421559353,0.564700636,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,33530,DB06403,10013781,118,21353,21,6640,0.016137284,1.747226945,1.091041001,2.929934636,0.052172884,DB0640310013781_,2.953192389,0.558029928,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,33532,DB14500,10013781,41,7768,14,4059,0.200138622,1.530210522,0.816001875,3.043010579,0.349167654,DB1450010013781_,1.052203088,0.425405322,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,33533,DB00211,10013968,120,1316,89,1542,0.001559074,1.579606763,1.178533788,2.123534002,0.00793499,DB0021110013968_,4.836473242,0.457175932,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,midodrine,DB00211
,33534,DB00448,10013968,225,4920,129,2995,0.614439903,1.061755392,0.847088136,1.335290456,0.755912039,DB0044810013968_,0.279830261,0.059923569,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lansoprazole,DB00448
,33535,DB00836,10013968,262,5273,160,3915,0.062247393,1.215755873,0.990405064,1.496085797,0.147642368,DB0083610013968_,1.912962361,0.195366001,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loperamide,DB00836
,33536,DB00930,10013968,42,1248,19,623,0.783692193,1.10344632,0.621663436,2.026743736,0.882236896,DB0093010013968_,0.125294669,0.098438301,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,colesevelam,DB00930
,33537,DB00972,10013968,118,2386,53,1126,0.801716685,1.050677278,0.747330122,1.493482421,0.892739804,DB0097210013968_,0.113460114,0.049434983,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azelastine,DB00972
,33538,DB01373,10013968,822,21898,248,7133,0.311099743,1.079659003,0.93315255,1.252628428,0.478607985,DB0137310013968_,0.736873419,0.076645253,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,33539,DB06209,10013968,28,436,39,618,1,1.017632297,0.593360464,1.72571234,1,DB0620910013968_,0,0.017478651,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prasugrel,DB06209
,33540,DB14500,10013968,557,7252,225,3848,0.000792278,1.313531029,1.117390252,1.54804847,0.004538525,DB1450010013968_,5.395153127,0.272718953,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,33541,DB00211,10016256,110,1326,96,1535,0.051255564,1.326304183,0.989212888,1.780704199,0.127379187,DB0021110016256_,2.06058692,0.282396264,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,midodrine,DB00211
,33542,DB00930,10016256,74,1216,27,615,0.160251751,1.385925616,0.870583974,2.265295544,0.297830537,DB0093010016256_,1.211230623,0.326368231,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,colesevelam,DB00930
,33543,DB00972,10016256,154,2350,60,1119,0.226952943,1.222070934,0.893049736,1.690186212,0.38211947,DB0097210016256_,0.96202197,0.200546906,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,azelastine,DB00972
,33545,DB14500,10016256,588,7221,271,3802,0.08599166,1.142424299,0.982160976,1.33126823,0.188326178,DB1450010016256_,1.66957983,0.133152582,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,33546,DB00126,10016807,87,10084,38,5907,0.137353036,1.341103115,0.904827283,2.021288486,0.266032315,DB0012610016807_,1.324137494,0.293492496,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,ascorbic acid,DB00126
,33548,DB00341,10016807,77,11328,20,5048,0.035351361,1.715592497,1.036831763,2.966556239,0.09617663,DB0034110016807_,2.341568879,0.5397585,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,cetirizine,DB00341
,33550,DB00524,10016807,140,1437,63,1281,7.61206978857956e-06,1.980526556,1.44598668,2.737029472,8.54144095593655e-05,DB0052410016807_,9.367995741,0.683362747,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,metolazone,DB00524
,33551,DB00836,10016807,62,5473,20,4055,0.001010327,2.296614776,1.365725958,4.021407116,0.005551676,DB0083610016807_,5.193655473,0.831436202,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,loperamide,DB00836
,33554,DB01373,10016807,135,22585,26,7355,0.012867459,1.690828799,1.104078271,2.683966236,0.04351386,DB0137310016807_,3.134675769,0.525218822,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,calcium,DB01373
,33556,DB06228,10016807,178,15734,67,16009,2.79717689866507e-13,2.703167448,2.028257528,3.638878121,1.35903502368598e-11,DB0622810016807_,25.02166112,0.994424214,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,rivaroxaban,DB06228
,33557,DB14500,10016807,188,7621,62,4011,0.00120354,1.595846031,1.188414202,2.168020768,0.006418798,DB1450010016807_,5.048524475,0.467404023,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,potassium,DB14500
,33558,DB00126,10016825,81,10090,33,5912,0.08015022,1.438152601,0.947113857,2.229147964,0.17865156,DB0012610016825_,1.722317962,0.363359374,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,ascorbic acid,DB00126
,33559,DB00175,10016825,38,8093,18,6088,0.106733655,1.588042305,0.883342537,2.959106644,0.221227309,DB0017510016825_,1.508564558,0.462502003,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,pravastatin,DB00175
,33563,DB00695,10016825,286,27763,87,20441,1.72574666809287e-14,2.420304291,1.896381991,3.11559966,9.83975079627355e-13,DB0069510016825_,27.64717582,0.883893272,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,furosemide,DB00695
,33564,DB00836,10016825,43,5492,12,4063,0.001566857,2.650689241,1.371029014,5.529487026,0.007965347,DB0083610016825_,4.83265481,0.974819697,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,loperamide,DB00836
,33567,DB00996,10016825,222,38731,84,22341,0.000838575,1.524455105,1.180160572,1.984811434,0.004759139,DB0099610016825_,5.347688555,0.421637038,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,gabapentin,DB00996
,33569,DB09140,10016825,111,3630,35,1763,0.025321888,1.54017242,1.039818434,2.33159009,0.074201319,DB0914010016825_,2.600973353,0.431894371,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,oxygen,DB09140
,33570,DB14500,10016825,67,7742,10,4063,3.1276038230219e-05,3.51587163,1.795747749,7.67232633,0.00029439,DB1450010016825_,8.130604065,1.257287469,female,10016825,Flushing,10047065,Vascular disorders,Vasc,potassium,DB14500
,33571,DB00126,10021097,182,9989,123,5822,0.208934912,0.862428588,0.680660658,1.095706642,0.359992861,DB0012610021097_,1.021671078,-0.14800293,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ascorbic acid,DB00126
,33572,DB00211,10021097,122,1314,142,1489,0.846803895,0.9735822,0.749216661,1.26375129,0.923061372,DB0021110021097_,0.080059555,-0.02677302,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,midodrine,DB00211
,33573,DB00341,10021097,110,11295,91,4977,1.44654358033223e-05,0.532634454,0.398961664,0.712598059,0.000150286,DB0034110021097_,8.80296936,-0.629919918,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,cetirizine,DB00341
,33574,DB00448,10021097,73,5072,48,3076,0.705756922,0.922345177,0.630234526,1.360618526,0.823674283,DB0044810021097_,0.193980115,-0.080835747,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,lansoprazole,DB00448
,33577,DB01373,10021097,230,22490,113,7268,0.000395018,0.657781587,0.522070054,0.832703971,0.002535546,DB0137310021097_,5.977346255,-0.418882337,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,calcium,DB01373
,33579,DB09140,10021097,247,3494,108,1690,0.412561495,1.106200008,0.87192879,1.410672253,0.582034667,DB0914010021097_,0.541225268,0.100930726,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,oxygen,DB09140
,33580,DB14500,10021097,188,7621,120,3953,0.088389082,0.812656964,0.640676215,1.033966012,0.192546999,DB1450010021097_,1.647415007,-0.207446197,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,potassium,DB14500
,33581,DB00169,10028735,276,38415,66,18109,1.87696665986212e-07,1.971306477,1.501195684,2.621081421,3.20884999378704e-06,DB0016910028735_,12.64959794,0.678696509,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,33583,DB00341,10028735,88,11317,27,5041,0.104279485,1.451788724,0.932600708,2.327921637,0.217469554,DB0034110028735_,1.525696419,0.372796399,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,33584,DB00374,10028735,458,17258,121,5603,0.04994409,1.228864253,1.001223451,1.517614894,0.124895861,DB0037410028735_,2.080275001,0.206090372,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,33585,DB00524,10028735,40,1537,15,1329,0.005841013,2.305096951,1.239257973,4.513243798,0.023172747,DB0052410028735_,3.764778393,0.835122737,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metolazone,DB00524
,33590,DB06228,10028735,86,15826,23,16053,4.87547129104407e-10,3.792285255,2.369807517,6.302416775,1.43426707202119e-08,DB0622810028735_,18.06002678,1.332968807,female,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,33591,DB14500,10028735,95,7714,12,4061,5.43153356662264e-08,4.167090875,2.274334232,8.357384377,1.04324340371703e-06,DB1450010028735_,13.77317604,1.42721816,female,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,33592,DB00211,10028813,129,1307,57,1574,1.76636499517047e-10,2.724625084,1.961646104,3.823057585,5.55037703503356e-09,DB0021110028813_,19.00939998,1.002330835,female,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,midodrine,DB00211
,33593,DB00448,10028813,324,4821,131,2993,4.32538194916637e-05,1.535400079,1.24288992,1.905515474,0.000390562,DB0044810028813_,7.847923247,0.428790985,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lansoprazole,DB00448
,33594,DB00930,10028813,69,1221,23,619,0.089803027,1.520577106,0.925976733,2.580981391,0.194895147,DB0093010028813_,1.635293573,0.419089938,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,colesevelam,DB00930
,33595,DB00972,10028813,152,2352,32,1147,6.8295470147934e-06,2.315982934,1.561884862,3.528914457,7.77624618946695e-05,DB0097210028813_,9.461851738,0.839834191,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,azelastine,DB00972
,33596,DB06209,10028813,36,428,28,629,0.01801033,1.888458179,1.102047701,3.26526216,0.056871879,DB0620910028813_,2.866954277,0.635760718,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,prasugrel,DB06209
,33597,DB06228,10028813,603,15309,269,15807,7.06708194899591e-32,2.314506734,1.997773728,2.686915539,1.78613700989767e-29,DB0622810028813_,66.1949125,0.839196591,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,33598,DB06403,10028813,1698,19773,320,6341,4.69725178499074e-19,1.701666333,1.503936954,1.929959396,4.47345156407542e-17,DB0640310028813_,37.64578631,0.531607967,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,33599,DB14500,10028813,555,7254,137,3936,7.20860292237199e-18,2.197980024,1.812217835,2.680601191,6.10235516310943e-16,DB1450010028813_,35.0326867,0.787538768,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,33600,DB00126,10030095,60,10111,35,5910,1,1.002020312,0.648877946,1.568766946,1,DB0012610030095_,0,0.002018274,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,33601,DB00169,10030095,216,38475,91,18084,0.425020245,1.115644463,0.868747836,1.442497226,0.593763335,DB0016910030095_,0.521274465,0.109432232,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,33602,DB00175,10030095,52,8079,27,6079,0.138063404,1.44911425,0.892464726,2.40285199,0.267024508,DB0017510030095_,1.320414833,0.370952508,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,33604,DB00341,10030095,73,11332,13,5055,0.001389068,2.504806443,1.375889611,4.931784755,0.007215672,DB0034110030095_,4.931499957,0.918211463,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,33605,DB00374,10030095,464,17252,163,5561,0.346378836,0.91757421,0.763940469,1.106587885,0.515795694,DB0037410030095_,0.662044533,-0.08602182,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,33606,DB00448,10030095,43,5102,11,3113,0.007279133,2.384919923,1.207197113,5.136784168,0.027609238,DB0044810030095_,3.589604864,0.869165549,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,33607,DB00524,10030095,92,1485,45,1299,0.001526418,1.78802317,1.228214706,2.635220288,0.007802778,DB0052410030095_,4.853275418,0.581110635,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,33608,DB00836,10030095,51,5484,20,4055,0.015639571,1.88540313,1.102434288,3.3442123,0.05094004,DB0083610030095_,2.97710602,0.63414166,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,33611,DB01373,10030095,110,22610,25,7356,0.109268792,1.431466293,0.919769967,2.309154293,0.224929925,DB0137310030095_,1.491966371,0.358699299,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,33613,DB06403,10030095,872,20599,303,6358,0.085819879,0.88829412,0.776109485,1.018773876,0.18807139,DB0640310030095_,1.670933653,-0.118452375,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,33614,DB09140,10030095,175,3566,63,1735,0.04737935,1.351436475,1.001532002,1.843061171,0.120174295,DB0914010030095_,2.118812129,0.301168083,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,33615,DB14500,10030095,93,7716,42,4031,0.466625151,1.15676146,0.793563774,1.711025007,0.633314071,DB1450010030095_,0.456788818,0.145624256,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,33616,DB00211,10030124,30,1406,21,1610,0.090396109,1.635566326,0.901130741,3.020527652,0.195875003,DB0021110030124_,1.630278563,0.491989121,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,midodrine,DB00211
,33617,DB00341,10030124,117,11288,46,5022,0.550526825,1.131573195,0.796663799,1.630959652,0.704654224,DB0034110030124_,0.350048059,0.123608872,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,33618,DB00448,10030124,63,5082,33,3091,0.526444783,1.161170506,0.748461202,1.831420948,0.684278119,DB0044810030124_,0.379390838,0.149428553,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,33619,DB00836,10030124,89,5446,37,4038,0.002687827,1.783405752,1.199826976,2.698624682,0.012364735,DB0083610030124_,4.392906802,0.57852488,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,33622,DB01373,10030124,273,22447,74,7307,0.187296482,1.200901659,0.924319932,1.576660021,0.333136285,DB0137310030124_,1.099203608,0.183072657,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,33624,DB14500,10030124,195,7614,73,4000,0.013399306,1.403289027,1.063983765,1.86762812,0.044949366,DB1450010030124_,3.102218629,0.338818787,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,33625,DB00211,10033371,52,1384,18,1613,2.74628223593866e-06,3.365641736,1.925718449,6.143863288,3.50332582245318e-05,DB0021110033371_,10.25921271,1.213618654,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,midodrine,DB00211
,33626,DB00374,10033371,826,16890,189,5535,7.13425657689809e-06,1.432145709,1.217638461,1.691356608,8.07770554054561e-05,DB0037410033371_,9.423817601,0.359173816,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,33627,DB00448,10033371,203,4942,63,3061,8.68176220734492e-07,1.995639109,1.491525644,2.701465413,1.26566899401032e-05,DB0044810033371_,11.27732463,0.690964354,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,33628,DB00836,10033371,166,5369,66,4009,1.09687942856084e-05,1.877919069,1.399346311,2.544940295,0.000117512,DB0083610033371_,9.048973342,0.630164285,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,33629,DB00972,10033371,104,2400,31,1148,0.023740405,1.604542499,1.057944168,2.495974946,0.070638052,DB0097210033371_,2.650186298,0.472838669,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,azelastine,DB00972
,33630,DB01240,10033371,404,5347,92,1484,0.100809876,1.218719391,0.961995521,1.556982453,0.21207574,DB0124010033371_,1.550811802,0.197800628,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,33632,DB06403,10033371,753,20718,189,6472,0.007986566,1.244565083,1.057007868,1.471192371,0.029747326,DB0640310033371_,3.515016018,0.218786138,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,33633,DB09140,10033371,226,3515,59,1739,8.92964577584746e-06,1.89489797,1.408138601,2.583587977,9.83514515894199e-05,DB0914010033371_,9.226963254,0.639164995,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,33635,DB00341,10033433,45,11360,13,5055,0.199769912,1.540290111,0.815675375,3.11513891,0.348784599,DB0034110033433_,1.053300743,0.431970782,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,33637,DB00524,10033433,40,1537,15,1329,0.005841013,2.305096951,1.239257973,4.513243798,0.023172747,DB0052410033433_,3.764778393,0.835122737,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,metolazone,DB00524
,33638,DB00820,10033433,750,11165,185,5631,1.46056293914456e-19,2.044562834,1.732639501,2.422338972,1.4514516769533e-17,DB0082010033433_,38.77138237,0.715183994,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,33639,DB00836,10033433,39,5496,14,4061,0.017913135,2.058208049,1.091473958,4.10988827,0.056670487,DB0083610033433_,2.870501708,0.721835725,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,loperamide,DB00836
,33642,DB00996,10033433,111,38842,42,22383,0.01866597,1.522956382,1.058405388,2.22805381,0.058515673,DB0099610033433_,2.838460646,0.420653434,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,33643,DB01240,10033433,1109,4642,300,1276,0.856875995,1.016143366,0.88033652,1.17509629,0.931317629,DB0124010033433_,0.07115489,0.016014447,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,epoprostenol,DB01240
,33645,DB06228,10033433,120,15792,29,16047,1.04142475153734e-14,4.204282503,2.781755141,6.548868627,6.11023428441046e-13,DB0622810033433_,28.12364109,1.436103649,female,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,rivaroxaban,DB06228
,33646,DB09140,10033433,148,3593,47,1751,0.012498728,1.534481602,1.092343588,2.189650844,0.042530786,DB0914010033433_,3.15752709,0.428192606,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,oxygen,DB09140
,33647,DB14500,10033433,73,7736,14,4059,0.000237254,2.735687556,1.528531292,5.255396392,0.001661439,DB1450010033433_,6.400071351,1.006382796,female,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,33648,DB00126,10036790,52,10119,23,5922,0.282497922,1.323119408,0.794605298,2.267501279,0.446590357,DB0012610036790_,0.806113531,0.279992137,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,33649,DB00169,10036790,170,38521,81,18094,0.945931352,0.985827567,0.751811115,1.301684165,0.984471238,DB0016910036790_,0.015650596,-0.014273821,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,33650,DB00175,10036790,33,8098,20,6086,0.489077352,1.240027856,0.690001247,2.282822709,0.652475482,DB0017510036790_,0.426981715,0.215133844,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,33652,DB00374,10036790,248,17468,71,5653,0.393880311,1.130384839,0.863406041,1.495885688,0.563819957,DB0037410036790_,0.573020303,0.12255814,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,33654,DB00451,10036790,171,47100,38,15381,0.029881381,1.469482727,1.028449086,2.148499489,0.084455398,DB0045110036790_,2.47153172,0.384910452,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,33656,DB00559,10036790,93,9566,17,3289,0.015206565,1.880920928,1.111743032,3.370848261,0.049849496,DB0055910036790_,2.998746899,0.631761512,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,33660,DB00996,10036790,119,38834,48,22377,0.036512943,1.428541917,1.013224691,2.042215865,0.098611359,DB0099610036790_,2.316568825,0.356654286,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,33661,DB01240,10036790,99,5652,24,1552,0.658525808,1.13267686,0.716355543,1.857330875,0.79150233,DB0124010036790_,0.233822456,0.124583734,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,33662,DB01373,10036790,81,22639,24,7357,0.734734238,1.096770442,0.687601456,1.810619668,0.846630548,DB0137310036790_,0.166490868,0.092369899,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,33664,DB06228,10036790,49,15863,28,16048,0.01627601,1.770366631,1.090302122,2.926977703,0.052537752,DB0622810036790_,2.946223286,0.571186661,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,33665,DB06403,10036790,141,21330,38,6623,0.481007328,1.152117044,0.7992861,1.696848847,0.64564165,DB0640310036790_,0.43751065,0.141601158,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,33666,DB09140,10036790,126,3615,28,1770,7.60860413227519e-05,2.203050485,1.446956624,3.461190227,0.00063089,DB0914010036790_,7.368378889,0.789842984,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,33692,DB00169,10040742,68,38623,23,18152,0.179037672,1.389527805,0.854621333,2.337478025,0.322700771,DB0016910040742_,1.131029792,0.328963981,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,33696,DB00374,10040742,77,17639,20,5704,0.477024566,1.244973084,0.752594021,2.152110423,0.642426832,DB0037410040742_,0.442502349,0.21911391,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,33698,DB00451,10040742,77,47194,13,15406,0.026752603,1.933410425,1.06626013,3.795928452,0.0774526,DB0045110040742_,2.558089139,0.659285503,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,33704,DB00996,10040742,40,38913,15,22410,0.163814542,1.535722983,0.829838717,2.993420716,0.302505637,DB0099610040742_,1.195655367,0.429001269,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,33709,DB06403,10040742,108,21363,32,6629,0.920615122,1.047299176,0.699410481,1.607941375,0.964812755,DB0640310040742_,0.035821232,0.046214637,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,33713,DB00169,10040882,75,38616,46,18129,0.171514719,0.765412493,0.52310723,1.130711461,0.312823575,DB0016910040882_,1.162115907,-0.267340383,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,33719,DB00451,10040882,80,47191,28,15391,0.73782419,0.931830347,0.598918225,1.489413002,0.848953281,DB0045110040882_,0.163751123,-0.070604512,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,33727,DB01373,10040882,46,22674,16,7365,0.769473883,0.933856926,0.518549586,1.768242605,0.873771294,DB0137310040882_,0.134936615,-0.068432036,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,33733,DB00175,10042772,67,8064,47,6059,0.775894811,1.071103921,0.725575158,1.592443873,0.877822795,DB0017510042772_,0.130310533,0.068689818,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,33734,DB00211,10042772,74,1362,56,1575,0.019522464,1.52785495,1.056579126,2.219709552,0.060673716,DB0021110042772_,2.802244686,0.423864758,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,midodrine,DB00211
,33736,DB00451,10042772,369,46902,144,15275,0.071480667,0.834530106,0.685895419,1.019895928,0.163850121,DB0045110042772_,1.808803166,-0.180886459,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,33737,DB00524,10042772,44,1533,30,1314,0.347772731,1.257043994,0.767681905,2.083595903,0.517329159,DB0052410042772_,0.659075936,0.228762928,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,metolazone,DB00524
,33738,DB00836,10042772,99,5436,87,3988,0.231148474,0.834837366,0.617652069,1.130048471,0.387298016,DB0083610042772_,0.948560814,-0.180518345,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,33741,DB01240,10042772,221,5530,53,1523,0.409972894,1.148372152,0.842511126,1.589294558,0.579402268,DB0124010042772_,0.545758279,0.13834542,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,epoprostenol,DB01240
,33742,DB01373,10042772,136,22584,59,7322,0.066142373,0.74734366,0.546044664,1.033663012,0.154414448,DB0137310042772_,1.868115072,-0.291230146,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,calcium,DB01373
,33744,DB06228,10042772,129,15783,106,15970,0.116398675,1.231389759,0.94403073,1.609118772,0.235729961,DB0622810042772_,1.445068363,0.208143417,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,33745,DB09140,10042772,180,3561,66,1732,0.05979982,1.326446335,0.988881155,1.797122498,0.143122082,DB0914010042772_,1.944057294,0.282503438,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,oxygen,DB09140
,33746,DB14500,10042772,60,7749,45,4028,0.07853645,0.693075511,0.46215545,1.046011904,0.175912278,DB1450010042772_,1.737769828,-0.366616323,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,potassium,DB14500
,33747,DB00126,10047899,213,9958,72,5873,3.06932152931889e-05,1.74470001,1.32692514,2.316809198,0.000289528,DB0012610047899_,8.147256822,0.556582627,NA,10047899,Weight increased,10022891,Investigations,Inv,ascorbic acid,DB00126
,33748,DB00169,10047899,698,37993,218,17957,5.21083484140139e-08,1.513303937,1.296523116,1.771951897,1.00378742254478e-06,DB0016910047899_,13.81173029,0.414295298,NA,10047899,Weight increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,33749,DB00175,10047899,138,7993,57,6049,0.00010272,1.83213599,1.333726974,2.545204851,0.000816734,DB0017510047899_,7.110196722,0.605482494,NA,10047899,Weight increased,10022891,Investigations,Inv,pravastatin,DB00175
,33751,DB00448,10047899,61,5084,25,3099,0.116953242,1.487256903,0.917551958,2.47845287,0.236552342,DB0044810047899_,1.441585774,0.396933419,NA,10047899,Weight increased,10022891,Investigations,Inv,lansoprazole,DB00448
,33752,DB00524,10047899,101,1476,45,1299,0.000161776,1.974847722,1.36487611,2.895678853,0.00120303,DB0052410047899_,6.722911665,0.680491293,NA,10047899,Weight increased,10022891,Investigations,Inv,metolazone,DB00524
,33753,DB00559,10047899,127,9532,53,3253,0.228128161,0.817756328,0.587488673,1.152092853,0.383533129,DB0055910047899_,0.958329275,-0.201190875,NA,10047899,Weight increased,10022891,Investigations,Inv,bosentan,DB00559
,33754,DB00695,10047899,681,27368,317,20211,7.0467110955694e-12,1.586455704,1.384708321,1.820632404,2.76865173612917e-10,DB0069510047899_,22.00749047,0.461502411,NA,10047899,Weight increased,10022891,Investigations,Inv,furosemide,DB00695
,33755,DB00836,10047899,89,5446,32,4043,0.000284792,2.064581163,1.361236092,3.203375414,0.001934052,DB0083610047899_,6.248138019,0.724927379,NA,10047899,Weight increased,10022891,Investigations,Inv,loperamide,DB00836
,33759,DB06228,10047899,123,15789,96,15980,0.057816454,1.296734938,0.983934219,1.713172914,0.139371377,DB0622810047899_,1.970613132,0.259849519,NA,10047899,Weight increased,10022891,Investigations,Inv,rivaroxaban,DB06228
,33760,DB09140,10047899,189,3552,48,1750,2.5970769903762e-05,1.939722356,1.398357895,2.735921202,0.000249504,DB0914010047899_,8.296037452,0.662544847,NA,10047899,Weight increased,10022891,Investigations,Inv,oxygen,DB09140
,33761,DB14500,10047899,195,7614,58,4015,9.55257342054854e-05,1.772801761,1.31252599,2.425796456,0.000766217,DB1450010047899_,7.174044814,0.572561211,NA,10047899,Weight increased,10022891,Investigations,Inv,potassium,DB14500
,33763,DB00169,10069868,71,38620,34,18141,0.916874004,0.980908231,0.642775559,1.523456657,0.962980568,DB0016910069868_,0.037722046,-0.01927637,NA,10069868,Device issue,10077536,Product issues,Prod,cholecalciferol,DB00169
,33766,DB00374,10069868,182,17534,46,5678,0.141413919,1.281209159,0.921263165,1.814003586,0.271834494,DB0037410069868_,1.302561876,0.247804287,NA,10069868,Device issue,10077536,Product issues,Prod,treprostinil,DB00374
,33769,DB00559,10069868,42,9617,15,3291,0.879389222,0.958178633,0.519763132,1.862687504,0.949348846,DB0055910069868_,0.051978954,-0.042721054,NA,10069868,Device issue,10077536,Product issues,Prod,bosentan,DB00559
,33770,DB00695,10069868,50,27999,19,20509,0.014317796,1.927570254,1.116114232,3.463117604,0.0474462,DB0069510069868_,3.048158841,0.656260274,NA,10069868,Device issue,10077536,Product issues,Prod,furosemide,DB00695
,33774,DB00996,10069868,80,38873,13,22412,2.22349559605866e-06,3.547898752,1.960737522,6.952268572,2.91131166836373e-05,DB0099610069868_,10.44432174,1.266355527,female,10069868,Device issue,10077536,Product issues,Prod,gabapentin,DB00996
,33778,DB06403,10069868,62,21409,24,6637,0.373646419,0.800865446,0.492238765,1.342915345,0.543423678,DB0640310069868_,0.609866009,-0.222062329,NA,10069868,Device issue,10077536,Product issues,Prod,ambrisentan,DB06403
,33781,DB06605,10022595,39,14034,44,12989,0.380689843,0.820371069,0.518778796,1.292949478,0.550726906,DB0660510022595_,0.596516226,-0.197998519,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,apixaban,DB06605
,33782,DB06228,10070863,76,15836,80,15996,0.810204211,0.959588329,0.691122229,1.33137877,0.897850953,DB0622810070863_,0.107751201,-0.041250911,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,33783,DB06605,10070863,66,14007,31,13002,0.001504492,1.976218955,1.270348177,3.13584086,0.007711693,DB0660510070863_,4.865017488,0.6811854,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,33784,DB00051,10002034,125,25606,68,11352,0.183709245,0.814978872,0.601270315,1.112682162,0.328579036,DB0005110002034_,1.112977873,-0.204593089,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,adalimumab,DB00051
,33786,DB00451,10002383,39,47232,17,15402,0.350846474,0.74809839,0.413263449,1.410736546,0.520561067,DB0045110002383_,0.652848074,-0.290220772,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,33787,DB00051,10003988,292,25439,159,11261,0.039908274,0.812975667,0.666962876,0.993811775,0.10551086,DB0005110003988_,2.248941393,-0.207054099,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,33788,DB00051,10007739,69,25662,30,11390,1,1.020859844,0.65559366,1.62472534,1,DB0005110007739_,0,0.020645256,NA,10007739,Cataract,10015919,Eye disorders,Eye,adalimumab,DB00051
,33789,DB00451,10007739,246,47025,65,15354,0.14620615,1.23569332,0.93605607,1.651269727,0.27870249,DB0045110007739_,1.277610408,0.211632205,NA,10007739,Cataract,10015919,Eye disorders,Eye,levothyroxine,DB00451
,33790,DB00051,10010774,158,25573,71,11349,0.942768085,0.987585549,0.741108743,1.327112324,0.981781625,DB0005110010774_,0.018386373,-0.012492154,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,33791,DB00051,10011224,301,25430,90,11330,0.000757869,1.49006995,1.17241048,1.909319843,0.004371428,DB0005110011224_,5.432665492,0.398823065,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,33794,DB00051,10012378,342,25389,130,11290,0.132341429,1.169837691,0.951966499,1.444778081,0.259088261,DB0005110012378_,1.350586501,0.156865013,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,adalimumab,DB00051
,33797,DB00051,10013774,98,25633,17,11403,0.000103423,2.564411086,1.52173604,4.581552462,0.000821293,DB0005110013774_,7.104630592,0.941728856,NA,10013774,Dry eye,10015919,Eye disorders,Eye,adalimumab,DB00051
,33798,DB00451,10013774,199,47072,18,15401,9.84773720771132e-10,3.617204539,2.229449545,6.23147955,2.73623438165636e-08,DB0045110013774_,17.41409808,1.285701501,female,10013774,Dry eye,10015919,Eye disorders,Eye,levothyroxine,DB00451
,33799,DB00051,10013950,77,25654,20,11400,0.03562659,1.710822144,1.034709792,2.956405106,0.096740179,DB0005110013950_,2.335726464,0.536974041,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,33801,DB00451,10013990,137,47134,44,15375,1,1.015664244,0.717996814,1.46165514,1,DB0045110013990_,0,0.015542826,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,33804,DB00051,10015090,56,25675,29,11391,0.482715199,0.856741134,0.537499742,1.392338789,0.647024291,DB0005110015090_,0.435371441,-0.154619467,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,33806,DB00451,10016454,151,47120,15,15404,4.62473268994005e-07,3.290958426,1.932106237,6.027574399,7.22932493339722e-06,DB0045110016454_,11.8373649,1.191178837,female,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,33807,DB00051,10017885,84,25647,16,11404,0.001028253,2.334380737,1.356337454,4.271619037,0.005637215,DB0005110017885_,5.178365064,0.847746647,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,33811,DB00451,10018304,58,47213,6,15413,0.003299598,3.155814586,1.364906902,8.952466478,0.014612126,DB0045110018304_,4.22590356,1.149246652,female,10018304,Glaucoma,10015919,Eye disorders,Eye,levothyroxine,DB00451
,33813,DB00451,10018830,45,47226,30,15389,0.003003933,0.488776552,0.301147936,0.803875665,0.01352606,DB0045110018830_,4.3031371,-0.715849842,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,33814,DB00051,10018836,82,25649,69,11351,0.000126921,0.525915637,0.376838827,0.735854059,0.000978181,DB0005110018836_,6.929815673,-0.642614466,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,33816,DB00451,10018852,74,47197,40,15379,0.011994562,0.602822702,0.404761785,0.909567075,0.041132038,DB0045110018852_,3.190967941,-0.506132152,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,33818,DB00451,10018964,82,47189,37,15382,0.109591431,0.722414949,0.484135055,1.09632651,0.225462793,DB0045110018964_,1.48960013,-0.325155583,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,33823,DB00451,10020947,67,47204,18,15401,0.52959559,1.214421052,0.712914827,2.172651711,0.686868482,DB0045110020947_,0.375612444,0.194267463,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,33827,DB00451,10023126,36,47235,19,15400,0.115373415,0.617745603,0.344957134,1.140446072,0.234222066,DB0045110023126_,1.451485612,-0.481678551,NA,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,levothyroxine,DB00451
,33829,DB00051,10028334,190,25541,68,11352,0.136327033,1.241848166,0.935848288,1.664846607,0.264561709,DB0005110028334_,1.329680752,0.216600727,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,33830,DB00051,10028372,98,25633,63,11357,0.02568876,0.689209869,0.496741612,0.962238486,0.075008783,DB0005110028372_,2.590150069,-0.372209456,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,33834,DB00051,10039101,90,25641,39,11381,1,1.024307271,0.69558159,1.533290917,1,DB0005110039101_,0,0.024016551,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,33835,DB00051,10039227,51,25680,21,11399,0.898331901,1.078006325,0.636625583,1.887722139,0.956365087,DB0005110039227_,0.044615548,0.07511334,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,33836,DB00451,10039227,70,47201,13,15406,0.072978914,1.757405391,0.963690833,3.464499943,0.166500368,DB0045110039227_,1.792757758,0.563838512,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,33838,DB00451,10040979,130,47141,45,15374,0.72547134,0.942143135,0.666166311,1.354275248,0.839115122,DB0045110040979_,0.175407369,-0.059598068,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,33843,DB00051,10043882,35,25696,21,11399,0.309944953,0.73933972,0.418359411,1.33729603,0.477390237,DB0005110043882_,0.739421015,-0.301997762,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,adalimumab,DB00051
,33844,DB00451,10043882,145,47126,35,15384,0.118623522,1.352387851,0.929071607,2.017349554,0.239148586,DB0045110043882_,1.430670221,0.301871808,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,levothyroxine,DB00451
,33845,DB00051,10047340,59,25672,17,11403,0.134897161,1.541556556,0.885989059,2.822254692,0.26248524,DB0005110047340_,1.337560428,0.432792657,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,adalimumab,DB00051
,33846,DB00051,10047513,127,25604,69,11351,0.186911067,0.816009777,0.603435316,1.111383345,0.332625771,DB0005110047513_,1.10073723,-0.203328942,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,adalimumab,DB00051
,33850,DB00451,10049816,59,47212,15,15404,0.421380099,1.283325492,0.718563755,2.436547535,0.590435306,DB0045110049816_,0.526895207,0.249454749,NA,10049816,Muscle tightness,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,33856,DB00451,10052251,54,47217,14,15405,0.484818595,1.258417451,0.689135495,2.453917474,0.648967829,DB0045110052251_,0.432372133,0.22985494,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,33866,DB00451,10057040,69,47202,20,15399,0.712679829,1.125511455,0.67575377,1.955875064,0.829206966,DB0045110057040_,0.187285498,0.118237559,NA,10057040,Temperature intolerance,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,33869,DB00051,10061623,395,25336,106,11314,1.62311093461738e-06,1.664040759,1.338051904,2.0844096,2.20882583051606e-05,DB0005110061623_,10.72046439,0.509248837,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,33874,DB00065,10012174,50,9414,32,4925,0.414432086,0.817458543,0.513487094,1.318469903,0.583669531,DB0006510012174_,0.538420328,-0.201555089,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,infliximab,DB00065
,33875,DB00497,10012174,270,18997,229,16146,1,1.002093377,0.836107326,1.201858923,1,DB0049710012174_,0,0.002091189,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,33885,DB00635,10060921,31,33022,24,23770,0.786270099,0.929773212,0.528018752,1.656009877,0.884022053,DB0063510060921_,0.12327327,-0.072814581,NA,10060921,Abdominal abscess,10021881,Infections and infestations,Infec,prednisone,DB00635
,33907,DB00186,10009657,52,16849,28,9980,0.729325399,1.100032689,0.681528828,1.81022351,0.842281112,DB0018610009657_,0.171641458,0.095339897,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,lorazepam,DB00186
,33908,DB00316,10009657,124,65350,61,36892,0.400052457,1.14758881,0.837774764,1.586380637,0.569941607,DB0031610009657_,0.562221367,0.137663054,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,33909,DB00451,10009657,71,47200,20,15399,0.627187982,1.158182501,0.696768075,2.00960847,0.766648183,DB0045110009657_,0.265727276,0.146851967,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,33910,DB00497,10009657,33,19234,34,16341,0.462725285,0.824608308,0.494783883,1.372820927,0.629964993,DB0049710009657_,0.462091028,-0.192846784,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,oxycodone,DB00497
,33912,DB00695,10009657,58,27991,36,20492,0.465738367,1.179461761,0.76474515,1.841380319,0.632541632,DB0069510009657_,0.45800924,0.1650582,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,furosemide,DB00695
,33915,DB00996,10009657,68,38885,28,22397,0.13892722,1.398802203,0.888298806,2.257350692,0.268329928,DB0099610009657_,1.315537981,0.335616301,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,gabapentin,DB00996
,33920,DB00316,10009895,47,65427,10,36943,0.00338644,2.653797751,1.323180468,5.891375174,0.014914636,DB0031610009895_,4.205412244,0.975991728,NA,10009895,Colitis ischaemic,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,33928,DB00186,10013538,53,16848,17,9991,0.025710439,1.848749341,1.05300281,3.407632383,0.075055407,DB0018610013538_,2.589528681,0.614509379,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,lorazepam,DB00186
,33929,DB00316,10013538,199,65275,77,36876,0.004657172,1.460016201,1.116551852,1.925546911,0.019308164,DB0031610013538_,3.947227254,0.378447532,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,33930,DB00451,10013538,163,47108,31,15388,0.004422424,1.717484491,1.163771976,2.611455168,0.018517468,DB0045110013538_,3.98904079,0.540860715,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,33931,DB00497,10013538,36,19231,25,16350,0.520652113,1.2242654,0.714544283,2.128520287,0.679729842,DB0049710013538_,0.38605985,0.202340991,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,oxycodone,DB00497
,33933,DB00695,10013538,73,27976,26,20502,0.001068675,2.057551748,1.298474298,3.356040912,0.005816259,DB0069510013538_,5.147098093,0.721516804,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,furosemide,DB00695
,33934,DB00722,10013538,93,25310,51,25981,0.000302723,1.871838453,1.315769267,2.689420602,0.002032201,DB0072210013538_,6.198635679,0.626921078,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,lisinopril,DB00722
,33936,DB00996,10013538,91,38862,29,22396,0.004333473,1.808358335,1.17865019,2.850702234,0.01822781,DB0099610013538_,4.004806821,0.592419436,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,gabapentin,DB00996
,33940,DB00557,10013968,235,5752,95,2972,0.050424626,1.27812493,0.998535018,1.646545484,0.12580164,DB0055710013968_,2.073048897,0.245394106,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxyzine,DB00557
,33942,DB00186,10024378,44,16857,29,9979,0.716246751,0.898181869,0.549119012,1.489630253,0.832149303,DB0018610024378_,0.183743403,-0.107382704,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,lorazepam,DB00186
,33943,DB00451,10024378,79,47192,29,15390,0.576949635,0.888368406,0.573583287,1.411187953,0.726177181,DB0045110024378_,0.319961243,-0.11836875,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,levothyroxine,DB00451
,33944,DB00497,10024378,32,19235,45,16330,0.029665401,0.603730186,0.371131239,0.97172076,0.083966516,DB0049710024378_,2.477337176,-0.504627893,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,oxycodone,DB00497
,33946,DB00722,10024378,52,25351,55,25977,0.922996409,0.968794919,0.649905141,1.442488505,0.966306952,DB0072210024378_,0.03427374,-0.031702332,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,lisinopril,DB00722
,33950,DB00186,10043554,163,16738,116,9892,0.135102483,0.830457683,0.649607534,1.064428181,0.262815924,DB0018610043554_,1.336301399,-0.185778305,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,lorazepam,DB00186
,33951,DB00497,10043554,141,19126,148,16227,0.075417738,0.808305858,0.636579362,1.025961033,0.170503181,DB0049710043554_,1.769001325,-0.212814755,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,oxycodone,DB00497
,33954,DB00996,10043554,156,38797,130,22295,0.002045127,0.689620198,0.542546653,0.877678593,0.009900759,DB0099610043554_,4.615143906,-0.371614271,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,gabapentin,DB00996
,33955,DB01069,10043554,56,6644,28,2367,0.170063906,0.712551281,0.443805814,1.168045005,0.310944157,DB0106910043554_,1.168141941,-0.338903396,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,promethazine,DB01069
,33956,DB01104,10043554,65,15398,27,7259,0.654685711,1.134899297,0.713609509,1.851270829,0.788400326,DB0110410043554_,0.23774929,0.126543922,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,sertraline,DB01104
,33958,DB00451,10054889,53,47218,23,15396,0.285463627,0.751364307,0.452421241,1.284904327,0.450097564,DB0045110054889_,0.798290911,-0.285864649,NA,10054889,Transaminases increased,10022891,Investigations,Inv,levothyroxine,DB00451
,33959,DB00497,10054889,29,19238,32,16343,0.30759541,0.769884331,0.44914245,1.314560108,0.474745036,DB0049710054889_,0.744977385,-0.261514995,NA,10054889,Transaminases increased,10022891,Investigations,Inv,oxycodone,DB00497
,33961,DB00722,10054889,23,25380,42,25990,0.025417685,0.560790154,0.321799898,0.954362854,0.074415603,DB0072210054889_,2.598089643,-0.578408501,NA,10054889,Transaminases increased,10022891,Investigations,Inv,lisinopril,DB00722
,33963,DB00996,10054889,38,38915,29,22396,0.255392862,0.754140029,0.45279957,1.268251165,0.41611662,DB0099610054889_,0.876789722,-0.282177214,NA,10054889,Transaminases increased,10022891,Investigations,Inv,gabapentin,DB00996
,33976,DB00188,10007515,34,7852,36,8792,0.811913385,1.057534582,0.641295103,1.74056294,0.89899083,DB0018810007515_,0.106482445,0.055940333,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,bortezomib,DB00188
,33977,DB00188,10040070,21,7865,37,8791,0.113356405,0.634410201,0.352504092,1.113598806,0.231126952,DB0018810040070_,1.464788144,-0.45505953,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,bortezomib,DB00188
,33979,DB00215,10017577,163,10940,67,5209,0.355559929,1.158356008,0.864671165,1.566591047,0.525311602,DB0021510017577_,0.643763664,0.147001766,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,33981,DB00404,10017577,327,19565,100,9762,1.2663682932934e-05,1.631548875,1.298519664,2.064995231,0.000133573,DB0040410017577_,8.920859439,0.489529794,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,33982,DB00787,10017577,124,16876,94,17154,0.035012021,1.340862948,1.016422064,1.773784755,0.095426272,DB0078710017577_,2.349401354,0.293313398,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,33993,DB00787,10037867,39,16961,29,17219,0.225387671,1.365266408,0.822412347,2.290279734,0.380213381,DB0078710037867_,0.967022655,0.311349581,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,34002,DB00331,10013538,65,24881,36,20716,0.056873302,1.503294832,0.985145925,2.326921091,0.137564621,DB0033110013538_,1.983661498,0.407659254,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,metformin,DB00331
,34009,DB00433,10016807,34,7622,26,5994,1,1.028380411,0.598364926,1.786790021,1,DB0043310016807_,0,0.027985148,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,prochlorperazine,DB00433
,34010,DB00722,10016807,162,25241,96,25936,1.52824833290382e-05,1.733934058,1.337975471,2.257342312,0.000157529,DB0072210016807_,8.755898191,0.550392849,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,34013,DB01254,10016807,74,3393,68,3080,1,0.987847321,0.698348438,1.399178778,1,DB0125410016807_,0,-0.012227126,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,dasatinib,DB01254
,34014,DB00186,10025482,512,16389,156,9852,1.19362704493929e-14,1.972906199,1.642990788,2.379734218,6.94894504456905e-13,DB0018610025482_,27.99501635,0.679507684,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,34015,DB00433,10025482,211,7445,104,5916,6.98854241147204e-05,1.612118684,1.265470048,2.064277507,0.000586132,DB0043310025482_,7.441965165,0.477549267,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,34016,DB00722,10025482,723,24680,417,25615,6.81157170211696e-22,1.799463911,1.590789102,2.03740028,8.56661063110738e-20,DB0072210025482_,43.9038297,0.587488793,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,34017,DB00973,10025482,102,3749,54,2967,0.017914682,1.494799956,1.060496577,2.127032136,0.056671971,DB0097310025482_,2.870475525,0.401992389,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,34018,DB01039,10025482,91,2882,57,2994,0.003444127,1.658383586,1.173061255,2.361214968,0.015127239,DB0103910025482_,4.19125827,0.505843384,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,34019,DB01254,10025482,59,3408,41,3107,0.191042804,1.311871431,0.863128757,2.010778812,0.337879162,DB0125410025482_,1.085066956,0.271454691,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,dasatinib,DB01254
,34027,DB00879,10005483,8,1769,80,3632,3.95123768506869e-07,0.205331087,0.08552816,0.425730408,6.25652304530304e-06,DB0087910005483_,11.98188595,-1.583131545,male,10005483,Blood creatinine increased,10022891,Investigations,Inv,emtricitabine,DB00879
,34029,DB01104,10005483,39,15424,39,7247,0.000959609,0.46985888,0.293350781,0.752662964,0.005325306,DB0110410005483_,5.235285131,-0.755322884,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,sertraline,DB01104
,34031,DB00169,10018100,35,38656,18,18157,0.769010615,0.913323862,0.503289126,1.713521645,0.87345277,DB0016910018100_,0.135301221,-0.090664738,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,34045,DB00222,10030124,45,3161,41,3087,0.828242349,1.07188757,0.684134422,1.683451827,0.909694342,DB0022210030124_,0.094646624,0.069421179,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,34046,DB00572,10030124,41,2861,30,2096,1,1.001234759,0.607836044,1.666487944,1,DB0057210030124_,0,0.001233997,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,atropine,DB00572
,34049,DB01104,10030124,144,15319,55,7231,0.194946553,1.235816755,0.898635906,1.720661024,0.342925892,DB0110410030124_,1.070240913,0.211732091,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,34072,DB00367,10028813,254,22546,14,453,0.001115152,0.364559678,0.211128501,0.681859351,0.006023793,DB0036710028813_,5.11203812,-1.009065015,male,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,levonorgestrel,DB00367
,34093,DB00136,10013968,108,1984,74,1608,0.285534912,1.182815548,0.865099598,1.624467782,0.450160087,DB0013610013968_,0.798152011,0.167897654,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcitriol,DB00136
,34094,DB01220,10013968,42,1252,35,1101,0.907703563,1.055264202,0.652535157,1.715817933,0.958771936,DB0122010013968_,0.042102046,0.053791164,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rifaximin,DB01220
,34095,DB01233,10013968,179,3242,85,1641,0.688100768,1.06592449,0.812926278,1.40649298,0.811956126,DB0123310013968_,0.208308972,0.063842488,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoclopramide,DB01233
,34098,DB01233,10018884,33,3388,19,1707,0.659171588,0.87511484,0.481589197,1.634003933,0.79180136,DB0123310018884_,0.233444727,-0.133400155,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,metoclopramide,DB01233
,34100,DB00571,10035664,84,5039,56,2553,0.125036395,0.760026653,0.53364433,1.089483902,0.248682024,DB0057110035664_,1.39158021,-0.274401776,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,propranolol,DB00571
,34101,DB01220,10035664,24,1270,35,1101,0.063629055,0.5945997,0.336114533,1.035623274,0.150019259,DB0122010035664_,1.8969916,-0.519866873,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,rifaximin,DB01220
,34102,DB01233,10035664,117,3304,75,1651,0.102101995,0.779589931,0.574743927,1.062761944,0.214109135,DB0123310035664_,1.541269419,-0.248987228,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,metoclopramide,DB01233
,34120,DB00169,10043414,91,38600,25,18150,0.016451821,1.711539644,1.088912343,2.782759609,0.052968655,DB0016910043414_,2.938054949,0.537393342,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,34122,DB01075,10043414,33,19915,39,11058,0.001855848,0.469838841,0.286166091,0.767163216,0.009150432,DB0107510043414_,4.693954201,-0.755365535,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,34150,DB00186,10036653,50,16851,20,9988,0.172610864,1.481790291,0.865789235,2.62943764,0.314276365,DB0018610036653_,1.157482537,0.393251013,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,34155,DB01234,10036653,47,31578,29,32859,0.02879596,1.686409097,1.039354824,2.779279761,0.082031192,DB0123410036653_,2.500655713,0.522601474,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,34158,DB00476,10003246,120,17137,25,6152,0.013568666,1.723188811,1.111500982,2.770973738,0.045397531,DB0047610003246_,3.092297549,0.544176534,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,34159,DB09072,10003246,51,6420,14,2521,0.269428164,1.430365078,0.778180679,2.803617188,0.431995565,DB0907210003246_,0.839339957,0.357929711,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium oxybate,DB09072
,34162,DB00476,10053762,476,16781,169,6008,0.963863572,1.008399929,0.842134218,1.212128809,1,DB0047610053762_,0,0.008364846,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,34163,DB06626,10012174,33,655,39,1413,0.014400411,1.824903076,1.10126294,3.007645048,0.04767345,DB0662610012174_,3.043380643,0.601526876,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,axitinib,DB06626
,34166,DB06626,10028813,55,633,88,1364,0.096062008,1.346612139,0.930714753,1.934535801,0.204861351,DB0662610028813_,1.585421865,0.297591912,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,axitinib,DB06626
,34168,DB06626,10047700,35,653,34,1418,0.001454842,2.234491063,1.340242532,3.728861769,0.00749961,DB0662610047700_,4.892904263,0.80401349,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,axitinib,DB06626
,34169,DB06626,10047895,48,640,62,1390,0.01151047,1.681040356,1.114935877,2.521713089,0.039851517,DB0662610047895_,3.222594814,0.519412861,NA,10047895,Weight decreased,10022891,Investigations,Inv,axitinib,DB06626
,34170,DB00448,10003549,132,5013,89,3035,0.439979306,0.897949027,0.678360947,1.193174118,0.6083059,DB0044810003549_,0.497077399,-0.107641975,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,34171,DB00060,10003549,284,9224,79,2386,0.553754663,0.929909319,0.71919227,1.213911832,0.707313037,DB0006010003549_,0.346281943,-0.072668204,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,34172,DB00108,10033775,74,10120,26,3269,0.726152093,0.919371919,0.579855726,1.500615477,0.839667763,DB0010810033775_,0.174748985,-0.084064539,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,34181,DB01076,10049438,44,25703,45,25538,0.91582611,0.971495484,0.626135954,1.506476984,0.962360651,DB0107610049438_,0.038366002,-0.028918658,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,34185,DB01076,10069868,53,25694,27,25556,0.004852529,1.952384384,1.205886743,3.229288938,0.019982567,DB0107610069868_,3.912895022,0.669051387,NA,10069868,Device issue,10077536,Product issues,Prod,atorvastatin,DB01076
,34195,DB00425,10064355,33,12662,34,7450,0.022667533,0.571112361,0.342525635,0.951154203,0.068124411,DB0042510064355_,2.686419667,-0.560169309,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,34197,DB00641,10064355,71,14053,58,12417,0.723701286,1.081656054,0.753112188,1.558985521,0.837570759,DB0064110064355_,0.17724953,0.07849325,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,34205,DB09072,10037660,49,6422,13,2522,0.256690377,1.480228262,0.789083813,2.979398362,0.417531889,DB0907210037660_,0.873394356,0.392196307,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,34209,DB00813,10053762,277,10295,199,9969,0.001586703,1.347858441,1.116948779,1.628864871,0.00804213,DB0081310053762_,4.823061283,0.298516993,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,34212,DB00996,10000087,442,38511,164,22261,8.07423251909233e-07,1.557884193,1.298341456,1.876707822,1.18664356591748e-05,DB0099610000087_,11.34179668,0.443328614,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,34213,DB01062,10000087,49,4437,13,1732,0.255950428,1.471313918,0.783594861,2.963844031,0.416728011,DB0106210000087_,0.875321523,0.386155823,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,oxybutynin,DB01062
,34214,DB01136,10000087,101,9783,87,11028,0.066983254,1.308636662,0.971350022,1.766076022,0.155920547,DB0113610000087_,1.858408714,0.268985879,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,34215,DB08827,10000087,83,1079,32,550,0.219604405,1.321912692,0.856989025,2.081990578,0.372972041,DB0882710000087_,0.986251819,0.279079697,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,lomitapide,DB08827
,34217,DB00338,10001760,430,33244,69,22203,2.67939220471692e-37,4.162048119,3.21956401,5.451186411,9.32818862264692e-35,DB0033810001760_,78.3574374,1.426007289,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,34218,DB00722,10001760,303,25100,71,25961,9.37157349408666e-37,4.413561119,3.396449927,5.803060637,3.19911440639049e-34,DB0072210001760_,77.12501914,1.484681873,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,34219,DB00996,10001760,429,38524,51,22374,3.39122802669445e-38,4.884933247,3.646542249,6.670044056,1.25547082650231e-35,DB0099610001760_,80.36296759,1.58615562,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,34223,DB01062,10012735,227,4259,77,1668,0.29562403,1.154546055,0.88194245,1.524863511,0.46145719,DB0106210012735_,0.773365993,0.143707241,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,oxybutynin,DB01062
,34241,DB00404,10007559,134,19758,53,9809,0.185065649,1.255144483,0.90589886,1.761200258,0.330229834,DB0040410007559_,1.107966399,0.227250692,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,alprazolam,DB00404
,34242,DB06403,10007559,287,21184,108,6553,0.094881923,0.822026759,0.655428057,1.037258291,0.203023096,DB0640310007559_,1.594435535,-0.195982331,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,ambrisentan,DB06403
,34243,DB00203,10011781,64,13814,21,8917,0.007169115,1.967193485,1.184557904,3.393817342,0.027300281,DB0020310011781_,3.600858277,0.6766079,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,sildenafil,DB00203
,34244,DB00404,10011781,74,19818,8,9854,1.41717160218586e-06,4.599709485,2.215377204,11.05492769,1.95932212045067e-05,DB0040410011781_,10.84032691,1.525993146,female,10011781,Cystitis,10021881,Infections and infestations,Infec,alprazolam,DB00404
,34245,DB01104,10011781,58,15405,10,7276,0.001602586,2.739322785,1.387117426,6.015531196,0.008108102,DB0110410011781_,4.814891492,1.007710731,female,10011781,Cystitis,10021881,Infections and infestations,Infec,sertraline,DB01104
,34247,DB00203,10016326,44,13834,19,8919,0.156234149,1.493000585,0.853085896,2.709576333,0.29238979,DB0020310016326_,1.229667471,0.40078791,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,34250,DB00404,10021143,76,19816,35,9827,0.762595446,1.076834137,0.71199431,1.657638817,0.868521505,DB0040410021143_,0.140962932,0.074025382,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,34251,DB01104,10021143,76,15387,33,7253,0.75797388,1.085578208,0.711810669,1.688491117,0.864803517,DB0110410021143_,0.145252945,0.082112756,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,34252,DB06403,10021143,254,21217,96,6565,0.100011345,0.818672254,0.643752711,1.048259255,0.210788659,DB0640310021143_,1.556899261,-0.200071454,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,34253,DB00404,10025482,717,19175,204,9658,1.08891964994186e-13,1.77024387,1.51007293,2.082401424,5.54157850894903e-12,DB0040410025482_,25.91874173,0.571117317,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,34254,DB01104,10025482,388,15075,117,7169,1.07701496731376e-05,1.577026891,1.276742384,1.960010367,0.000115666,DB0110410025482_,9.064800831,0.45554136,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,34258,DB00404,10033318,83,19809,16,9846,0.000233385,2.578358575,1.496916334,4.721887429,0.001638496,DB0040410033318_,6.413976454,0.947152985,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,alprazolam,DB00404
,34259,DB01104,10033318,54,15409,29,7257,0.557703992,0.876969706,0.548057709,1.429717566,0.710768719,DB0110410033318_,0.341408192,-0.13128283,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,sertraline,DB01104
,34260,DB00203,10047895,457,13421,208,8730,1.87502388522483e-05,1.429142074,1.20760722,1.695811579,0.000188759,DB0020310047895_,8.575038922,0.357074316,NA,10047895,Weight decreased,10022891,Investigations,Inv,sildenafil,DB00203
,34261,DB06403,10047895,386,21085,137,6524,0.177018903,0.871805404,0.714079401,1.069488515,0.320063751,DB0640310047895_,1.139235082,-0.137189041,NA,10047895,Weight decreased,10022891,Investigations,Inv,ambrisentan,DB06403
,34266,DB01104,10055798,55,15408,26,7260,1,0.996735095,0.613924227,1.657339498,1,DB0110410055798_,0,-0.003270246,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,sertraline,DB01104
,34267,DB06403,10055798,110,21361,38,6623,0.561326575,0.89750578,0.614841508,1.335815044,0.713776258,DB0640310055798_,0.33718573,-0.108135718,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,ambrisentan,DB06403
,34268,DB00203,10060945,46,13832,7,8931,5.33181738452229e-05,4.242801055,1.901475105,11.14277666,0.000466379,DB0020310060945_,7.670512446,1.445223677,female,10060945,Bacterial infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,34272,DB00203,10062355,326,13552,93,8845,1.3192978660487e-13,2.287772107,1.808659069,2.917016014,6.63688888212253e-12,DB0020310062355_,25.7383778,0.827578465,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,34273,DB00404,10062355,132,19760,54,9808,0.242147016,1.213282395,0.876767064,1.699302526,0.400366996,DB0040410062355_,0.915373663,0.19332941,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,34279,DB00316,10017888,65,65409,19,36934,0.011891878,1.931726497,1.143775167,3.411995601,0.040873228,DB0031610017888_,3.197280003,0.658414161,NA,10017888,Gastroenteritis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,34280,DB00451,10017888,62,47209,10,15409,0.038958382,2.02354518,1.02972879,4.428193542,0.103552054,DB0045110017888_,2.267680859,0.704851013,NA,10017888,Gastroenteritis,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,34282,DB00451,10021789,439,46832,109,15310,0.009552154,1.316630751,1.06433818,1.640570163,0.034333156,DB0045110021789_,3.371643755,0.275076012,NA,10021789,Infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,34283,DB01611,10021789,216,11697,46,2315,0.674583029,0.929326049,0.671013577,1.311307844,0.802671507,DB0161110021789_,0.219809731,-0.073295634,NA,10021789,Infection,10021881,Infections and infestations,Infec,hydroxychloroquine,DB01611
,34286,DB00722,10007636,41,25362,38,25994,0.735748214,1.105829047,0.693463102,1.767384067,0.847316062,DB0072210007636_,0.165681499,0.100595323,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,lisinopril,DB00722
,34295,DB00575,10008190,57,5187,44,3785,0.839564434,0.945328991,0.625224457,1.437666104,0.917802954,DB0057510008190_,0.085772558,-0.056222273,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,34296,DB00927,10008190,71,7426,56,4960,0.363753467,0.846847378,0.587023439,1.226822317,0.533317778,DB0092710008190_,0.628637825,-0.166234792,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,34298,DB00722,10019465,35,25368,27,26005,0.309505018,1.328834648,0.781214211,2.283258629,0.476952843,DB0072210019465_,0.740337655,0.284302353,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,34301,DB00575,10028596,34,5210,39,3790,0.056929854,0.634230531,0.387566764,1.03325354,0.137657074,DB0057510028596_,1.982989659,-0.455342776,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,clonidine,DB00575
,34303,DB00575,10043607,36,5208,24,3805,0.793799167,1.095923551,0.634838455,1.923598693,0.888291402,DB0057510043607_,0.118455435,0.091597433,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,clonidine,DB00575
,34304,DB00927,10043607,70,7427,59,4957,0.206156437,0.791889312,0.550899048,1.141581373,0.356642223,DB0092710043607_,1.031022176,-0.233333655,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,famotidine,DB00927
,34305,DB01067,10043607,43,4318,37,4786,0.263427846,1.288080445,0.808897385,2.060137747,0.425228049,DB0106710043607_,0.855129668,0.253153083,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,glipizide,DB01067
,34307,DB00927,10061024,35,7462,24,4992,1,0.975600806,0.563259492,1.716527614,1,DB0092710061024_,0,-0.024701787,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,famotidine,DB00927
,34308,DB00316,10022000,639,64835,302,36651,0.010526202,1.196073154,1.040806532,1.376975957,0.037087313,DB0031610022000_,3.294480334,0.179043819,NA,10022000,Influenza,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,34309,DB00904,10022000,263,22806,113,14343,0.000638794,1.463739512,1.168502846,1.843244963,0.003797083,DB0090410022000_,5.573522122,0.380994471,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ondansetron,DB00904
,34312,DB01281,10003239,241,8691,43,1755,0.519382058,1.131751332,0.811726468,1.61099923,0.678594164,DB0128110003239_,0.387732027,0.123766284,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,abatacept,DB01281
,34313,DB00051,10003549,260,25471,129,11291,0.294512597,0.893458149,0.719796872,1.113513473,0.460392139,DB0005110003549_,0.775676676,-0.112655784,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,34314,DB01281,10003549,59,8873,16,1782,0.278528573,0.740598952,0.419393485,1.3822302,0.442337233,DB0128110003549_,0.815682718,-0.300296026,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,34315,DB00051,10013573,417,25314,156,11264,0.06801906,1.189423177,0.985856993,1.441026973,0.157744926,DB0005110013573_,1.846775946,0.173468464,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,34316,DB01281,10013573,139,8793,23,1775,0.457636496,1.219945294,0.778283946,1.993973415,0.624945745,DB0128110013573_,0.470090441,0.198806016,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,abatacept,DB01281
,34317,DB00051,10015150,222,25509,67,11353,0.004806179,1.474677583,1.116339283,1.969975365,0.019828975,DB0005110015150_,3.920611006,0.388439378,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,34318,DB01281,10015150,50,8882,14,1784,0.31158092,0.717367355,0.389407935,1.408318738,0.479025691,DB0128110015150_,0.736001048,-0.332167219,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,abatacept,DB01281
,34319,DB01281,10016256,250,8682,45,1753,0.527491783,1.121720991,0.810241179,1.583792262,0.685069495,DB0128110016256_,0.378234994,0.114864105,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,34320,DB00051,10017533,89,25642,18,11402,0.001508493,2.198562698,1.313670934,3.879962319,0.007730695,DB0005110017533_,4.862556538,0.787803828,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,adalimumab,DB00051
,34322,DB01281,10017577,57,8875,15,1783,0.342919211,0.763446892,0.425307264,1.455346787,0.51226913,DB0128110017577_,0.668905148,-0.269911716,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,34325,DB01281,10021789,253,8679,45,1753,0.479288347,1.135573247,0.820519102,1.602913368,0.644364554,DB0128110021789_,0.439490635,0.127137587,NA,10021789,Infection,10021881,Infections and infestations,Infec,abatacept,DB01281
,34326,DB00051,10022004,143,25588,54,11366,0.352832659,1.176272429,0.853721388,1.64137319,0.522593931,DB0005110022004_,0.648950539,0.16235048,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,34328,DB01281,10022052,69,8863,8,1790,0.166833932,1.741848168,0.834450123,4.202120083,0.306595114,DB0128110022052_,1.182227249,0.554946715,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,34329,DB00051,10022061,504,25227,91,11329,2.33727458836912e-18,2.487172414,1.983612497,3.148254729,2.07902749764069e-16,DB0005110022061_,36.10946125,0.911146489,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,34331,DB01281,10022086,90,8842,11,1787,0.139563378,1.65350093,0.879083406,3.437429269,0.269212445,DB0128110022086_,1.312254452,0.502894816,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,34332,DB00051,10028391,135,25596,61,11359,0.93815151,0.982136814,0.720052725,1.352849132,0.978020205,DB0005110028391_,0.02222495,-0.018024659,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,34333,DB01281,10028391,47,8885,6,1792,0.358354987,1.579827226,0.672687415,4.528854886,0.528094684,DB0128110028391_,0.638479685,0.457315491,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,abatacept,DB01281
,34334,DB01281,10033371,307,8625,60,1738,0.886971015,1.031048423,0.775550159,1.390165742,0.953012984,DB0128110033371_,0.048126751,0.030576171,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,34335,DB01281,10037660,97,8835,18,1780,0.899979343,1.0857327,0.650042711,1.913539585,0.956571579,DB0128110037660_,0.044399659,0.082255059,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,34336,DB00051,10042674,252,25479,60,11360,4.64547009526863e-06,1.872573084,1.406722014,2.527223043,5.54728251904863e-05,DB0005110042674_,9.799617293,0.627313466,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,34337,DB01281,10042674,74,8858,15,1783,1,0.993016182,0.563307822,1.867378877,1,DB0128110042674_,0,-0.007008319,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,34338,DB01281,10047700,113,8819,7,1791,0.000507023,3.278132693,1.536434643,8.352873351,0.003123726,DB0128110047700_,5.768728864,1.18727396,female,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,abatacept,DB01281
,34339,DB01281,10048959,118,8814,22,1776,0.820192211,1.080783111,0.679208445,1.795266226,0.904288487,DB0128110048959_,0.100606847,0.077685882,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,34340,DB00051,10051572,44,25687,6,11414,0.00315495,3.258256352,1.382961267,9.358283068,0.014096186,DB0005110051572_,4.261851012,1.181192191,female,10051572,Injection site discolouration,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,34342,DB00051,10053156,33,25698,19,11401,0.368998568,0.770535807,0.425276324,1.434960292,0.538612239,DB0005110053156_,0.618759375,-0.260669152,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,34344,DB00051,10053425,310,25421,64,11356,1.77990154665646e-09,2.16374845,1.646927388,2.880665132,4.69490337720673e-08,DB0005110053425_,16.87420321,0.771842111,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,34348,DB00051,10061218,123,25608,42,11378,0.150894716,1.301158005,0.909156613,1.895343485,0.285176921,DB0005110061218_,1.254645518,0.263254641,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,34369,DB00741,10010305,42,4052,37,3137,0.57075234,0.878822475,0.549899836,1.409737903,0.721226155,DB0074110010305_,0.326802522,-0.129172364,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,hydrocortisone,DB00741
,34371,DB00316,10013911,229,65245,146,36807,0.258037264,0.884846919,0.715557893,1.097027814,0.418957741,DB0031610013911_,0.869985221,-0.122340622,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,34373,DB14500,10013911,51,7758,21,4052,0.386056549,1.268461798,0.748282449,2.22348601,0.55619482,DB1450010013911_,0.58663665,0.237804984,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,potassium,DB14500
,34374,DB00741,10037844,181,3913,116,3058,0.106890229,1.219372036,0.955666205,1.56073313,0.221473022,DB0074110037844_,1.507454493,0.198336002,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocortisone,DB00741
,34376,DB14500,10037844,192,7617,91,3982,0.485752135,1.103005913,0.852435985,1.435882025,0.649787265,DB1450010037844_,0.431110254,0.098039101,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,potassium,DB14500
,34381,DB00741,10013968,198,3896,109,3065,0.003248274,1.428988167,1.119780317,1.831368352,0.014429059,DB0074110013968_,4.238511097,0.356966618,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrocortisone,DB00741
,34384,DB00571,10047571,37,5086,13,2596,0.294277697,1.452670352,0.753093903,2.983773408,0.460079658,DB0057110047571_,0.776355634,0.373403485,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,propranolol,DB00571
,34385,DB00996,10047571,275,38678,98,22327,3.06431110743393e-05,1.619830515,1.280964752,2.06263295,0.00028916,DB0099610047571_,8.148531638,0.482321524,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,gabapentin,DB00996
,34387,DB01373,10047571,138,22582,31,7350,0.072352104,1.448867832,0.974673294,2.21606791,0.165371744,DB0137310047571_,1.799559347,0.370782446,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,calcium,DB01373
,34388,DB00203,10038687,120,13758,70,8868,0.55071966,1.104992869,0.81506356,1.507711313,0.704806401,DB0020310038687_,0.349832123,0.099838882,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,34389,DB00682,10038687,87,19372,55,16309,0.108566961,1.331696777,0.938691466,1.903266601,0.223870916,DB0068210038687_,1.49668566,0.286453901,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,34390,DB01240,10038687,60,5691,23,1553,0.178655651,0.711915701,0.431994692,1.210680325,0.322193056,DB0124010038687_,1.132604361,-0.339795772,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,34399,DB00370,10003239,68,4473,43,3620,0.213097055,1.279784462,0.858574823,1.926071829,0.365152455,DB0037010003239_,1.007440327,0.246691675,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,mirtazapine,DB00370
,34400,DB00370,10003549,148,4393,105,3558,0.33534099,1.141578679,0.879336059,1.486333645,0.504560937,DB0037010003549_,0.68406666,0.13241211,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,34401,DB00370,10003988,52,4489,44,3619,0.836845721,0.95275298,0.623799208,1.461041072,0.915738214,DB0037010003988_,0.088024748,-0.048399611,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,mirtazapine,DB00370
,34406,DB00370,10016322,63,4478,48,3615,0.774194694,1.059561588,0.714335625,1.580335459,0.876821317,DB0037010016322_,0.13145205,0.057855226,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,34407,DB01611,10016322,115,11798,20,2341,0.643116504,1.140924545,0.70382931,1.941468878,0.779503703,DB0161110016322_,0.24909784,0.131838938,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,34408,DB00370,10017577,44,4497,49,3614,0.141554214,0.721678315,0.468033209,1.109822027,0.271974891,DB0037010017577_,1.302045528,-0.326175787,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,34410,DB01611,10020937,126,11787,23,2338,0.824509758,1.086662489,0.691044795,1.780527299,0.907015945,DB0161110020937_,0.097595249,0.083111062,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,hydroxychloroquine,DB01611
,34411,DB00370,10022000,40,4501,24,3639,0.258914232,1.347428546,0.791009782,2.341385505,0.419998532,DB0037010022000_,0.867504062,0.298197995,NA,10022000,Influenza,10021881,Infections and infestations,Infec,mirtazapine,DB00370
,34412,DB01611,10022000,139,11774,17,2344,0.064588106,1.627739197,0.97838861,2.879873919,0.151733704,DB0161110022000_,1.885628245,0.487192056,NA,10022000,Influenza,10021881,Infections and infestations,Infec,hydroxychloroquine,DB01611
,34415,DB01611,10022061,186,11727,18,2343,0.00223092,2.064451883,1.267506343,3.567603194,0.010634697,DB0161110022061_,4.543633287,0.724864759,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,34423,DB01611,10022086,314,11599,24,2337,3.56421080066276e-07,2.635959835,1.734423139,4.186798903,5.70208648176632e-06,DB0161110022086_,12.0746784,0.969247379,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,34425,DB01611,10022095,183,11730,13,2348,5.95103080715337e-05,2.817657326,1.603571479,5.401733354,0.000512106,DB0161110022095_,7.576978494,1.035905804,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,34428,DB01611,10028391,104,11809,16,2345,0.389063471,1.290730058,0.75677853,2.346079257,0.558964408,DB0161110028391_,0.581669479,0.255207995,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,34429,DB00370,10033425,61,4480,40,3623,0.315802041,1.23324365,0.81216746,1.890907825,0.483437096,DB0037010033425_,0.726834073,0.209647812,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,mirtazapine,DB00370
,34430,DB01611,10033425,325,11588,46,2315,0.028170409,1.411423042,1.030345162,1.97280193,0.080624914,DB0161110033425_,2.517947576,0.344598445,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,34435,DB00005,10040986,66,128016,18,42401,0.528983681,1.214453415,0.712373058,2.17405529,0.686278032,DB0000510040986_,0.376472439,0.194294111,NA,10040986,"Sleep disorder due to general medical condition, insomnia type",10037175,Psychiatric disorders,Psych,etanercept,DB00005
,34439,DB00370,10047895,120,4421,79,3584,0.17021936,1.23137524,0.915947271,1.663071235,0.311141578,DB0037010047895_,1.167507236,0.208131626,NA,10047895,Weight decreased,10022891,Investigations,Inv,mirtazapine,DB00370
,34445,DB01611,10061218,54,11859,12,2349,0.739223269,0.891328132,0.470030047,1.833627168,0.850033188,DB0161110061218_,0.162479886,-0.115042645,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,34449,DB00264,10007515,298,29309,344,24548,5.56378678847467e-05,0.725569731,0.618638583,0.850579208,0.000483692,DB0026410007515_,7.634063178,-0.320798097,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,metoprolol,DB00264
,34450,DB00381,10007515,245,29115,265,22622,0.000229103,0.718360181,0.600797787,0.858665452,0.001615335,DB0038110007515_,6.428212607,-0.330784191,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,amlodipine,DB00381
,34451,DB00264,10007625,49,29558,57,24835,0.097721511,0.722298219,0.482589914,1.077544438,0.207447093,DB0026410007625_,1.572878945,-0.325317179,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,metoprolol,DB00264
,34452,DB00264,10020646,65,29542,188,24704,2.40615981802033e-20,0.289129481,0.214515195,0.385467622,2.56056319095807e-18,DB0026410020646_,40.50630444,-1.240880661,male,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,34453,DB00381,10020646,87,29273,134,22753,5.67499290077967e-07,0.50465956,0.380547351,0.666291134,8.6800807912129e-06,DB0038110020646_,11.65447972,-0.683871216,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,34455,DB00264,10020993,94,29513,103,24789,0.062852208,0.766550911,0.573045528,1.02438515,0.148698838,DB0026410020993_,1.905832237,-0.265854163,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,34456,DB00381,10020993,131,29229,105,22782,0.843820432,0.972423959,0.746056366,1.270112001,0.920955013,DB0038110020993_,0.08234409,-0.027963398,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,34458,DB00661,10022523,59,3469,56,1539,8.97458012605058e-05,0.467477384,0.317085148,0.689920176,0.000728189,DB0066110022523_,7.224949877,-0.760404308,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,verapamil,DB00661
,34461,DB00264,10042464,62,29545,53,24839,0.92570095,0.983478099,0.670277597,1.447513853,0.968288692,DB0026410042464_,0.032225001,-0.01665991,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,34464,DB00264,10058151,33,29574,31,24861,0.707070913,0.894874278,0.531099585,1.511249958,0.824824541,DB0026410058151_,0.192584593,-0.111072042,NA,10058151,Pulseless electrical activity,10007541,Cardiac disorders,Card,metoprolol,DB00264
,34469,DB00563,10005191,139,46507,41,15307,0.60390932,1.115838975,0.782163717,1.622780486,0.747404783,DB0056310005191_,0.291148362,0.109606566,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,34472,DB00563,10013911,63,46583,15,15333,0.294873957,1.382421277,0.777843599,2.615260831,0.460791094,DB0056310013911_,0.774810497,0.32383651,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,34474,DB00626,10016256,36,831,24,422,0.329950105,0.761921799,0.435680912,1.353782682,0.498590847,DB0062610016256_,0.695969464,-0.271911355,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,bacitracin,DB00626
,34476,DB00563,10021789,871,45775,243,15105,0.022741044,1.18277338,1.023562172,1.370826894,0.068286781,DB0056310021789_,2.684039074,0.167862003,NA,10021789,Infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,34478,DB00563,10023547,92,46554,32,15316,0.75570953,0.945854733,0.626114238,1.462696621,0.862950453,DB0056310023547_,0.147398002,-0.055666281,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,methotrexate,DB00563
,34488,DB00563,10034839,63,46583,8,15340,0.008253454,2.593365628,1.238423974,6.268706494,0.030538012,DB0056310034839_,3.488783072,0.952956502,NA,10034839,Pharyngitis streptococcal,10021881,Infections and infestations,Infec,methotrexate,DB00563
,34493,DB00563,10044016,44,46602,17,15331,0.554827489,0.85150054,0.476606866,1.590122025,0.708321946,DB0056310044016_,0.344856563,-0.160755145,NA,10044016,Tooth abscess,10021881,Infections and infestations,Infec,methotrexate,DB00563
,34498,DB00563,10062244,70,46576,16,15332,0.211831846,1.44013755,0.827662018,2.657695966,0.36360075,DB0056310062244_,1.011698855,0.36473863,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,34501,DB00338,10007515,134,33540,142,22130,9.70072965775876e-05,0.622661156,0.487709013,0.794527284,0.000775852,DB0033810007515_,7.161549094,-0.473752799,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,omeprazole,DB00338
,34503,DB00588,10007515,59,16465,50,8418,0.010866027,0.603288273,0.406480055,0.898559235,0.038043759,DB0058810007515_,3.269018228,-0.505360131,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,fluticasone propionate,DB00588
,34506,DB00956,10007515,67,5747,51,3416,0.212896391,0.780909813,0.533025635,1.150067182,0.364903761,DB0095610007515_,1.008121628,-0.247295613,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,hydrocodone,DB00956
,34507,DB01098,10007515,30,8119,51,7158,0.004953275,0.518636349,0.318544721,0.830958615,0.020321028,DB0109810007515_,3.896099079,-0.656552317,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,rosuvastatin,DB01098
,34508,DB01136,10007515,110,9774,156,10959,0.063660548,0.790627891,0.612722349,1.017258827,0.150059859,DB0113610007515_,1.896721002,-0.234927851,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,carvedilol,DB01136
,34509,DB01409,10007515,23,6008,49,3917,1.31852830191799e-06,0.306060415,0.177660822,0.512983381,1.832761312317e-05,DB0140910007515_,10.90710172,-1.183972761,male,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,tiotropium,DB01409
,34512,DB11089,10007515,56,10119,68,8339,0.036973442,0.678687002,0.467230513,0.982344317,0.099523495,DB1108910007515_,2.307361529,-0.387595227,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,docusate,DB11089
,34515,DB00338,10028372,268,33406,193,22079,0.364512771,0.917769277,0.759266521,1.111032631,0.534143293,DB0033810028372_,0.627091137,-0.085809252,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,34516,DB00390,10028372,35,4110,22,3279,0.423465228,1.269202457,0.722367651,2.275963257,0.592283485,DB0039010028372_,0.5237699,0.238388716,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,digoxin,DB00390
,34517,DB00581,10028372,30,2083,20,2049,0.201185472,1.475373448,0.807590569,2.750641823,0.350394919,DB0058110028372_,1.04869442,0.388911143,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,lactulose,DB00581
,34518,DB00682,10028372,161,19298,111,16253,0.112194161,1.22157849,0.952351895,1.571573725,0.229344288,DB0068210028372_,1.472530964,0.200143867,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,34519,DB00695,10028372,256,27793,177,20351,0.590993602,1.059060457,0.870207729,1.291174164,0.73746193,DB0069510028372_,0.304540812,0.057382153,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,34522,DB00956,10028372,63,5751,31,3436,0.393811841,1.214130141,0.776133814,1.93566041,0.563783352,DB0095610028372_,0.573085229,0.194027887,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocodone,DB00956
,34523,DB01098,10028372,72,8077,86,7123,0.06513084,0.738343112,0.531336001,1.02345834,0.152663112,DB0109810028372_,1.879521667,-0.303346641,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,34524,DB01136,10028372,74,9810,83,11032,1,1.00262574,0.721950621,1.390184009,1,DB0113610028372_,0,0.002622299,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,carvedilol,DB01136
,34525,DB01409,10028372,44,5987,19,3947,0.15469294,1.526648932,0.871460473,2.773081915,0.290378579,DB0140910028372_,1.236569763,0.423075093,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,tiotropium,DB01409
,34528,DB11089,10028372,91,10084,90,8317,0.230522489,0.833946744,0.61529284,1.130419456,0.386532509,DB1108910028372_,0.950539303,-0.181585735,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,34529,DB13867,10028372,41,4509,21,2533,0.79139659,1.0967771,0.631670844,1.958242938,0.887091809,DB1386710028372_,0.119806797,0.092375971,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone,DB13867
,34531,DB00338,10028596,162,33512,189,22083,1.25532500246033e-07,0.564844977,0.454744431,0.700950199,2.23703170777423e-06,DB0033810028596_,13.0103607,-0.571203963,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,omeprazole,DB00338
,34532,DB00390,10028596,31,4114,33,3268,0.257008815,0.746253854,0.441010875,1.259906416,0.417892709,DB0039010028596_,0.872530557,-0.29268945,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,digoxin,DB00390
,34536,DB00956,10028596,33,5781,45,3422,0.0003512,0.434125292,0.267832207,0.697161069,0.002300063,DB0095610028596_,6.074818883,-0.834422094,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,hydrocodone,DB00956
,34537,DB01409,10028596,68,5963,49,3917,0.635399627,0.911603945,0.620697968,1.347421781,0.773416276,DB0140910028596_,0.256937855,-0.092549654,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,tiotropium,DB01409
,34540,DB11089,10028596,59,10116,57,8350,0.401467556,0.854396454,0.582807463,1.253384503,0.571258216,DB1108910028596_,0.559913955,-0.157359961,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,docusate,DB11089
,34561,DB00581,10035664,92,2021,114,1955,0.086674564,0.780711493,0.582371509,1.044335862,0.189513864,DB0058110035664_,1.663293094,-0.247549604,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,lactulose,DB00581
,34562,DB00874,10035664,240,3095,166,1810,0.121218255,0.845548461,0.684812192,1.045847736,0.243185912,DB0087410035664_,1.413929057,-0.167769795,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,guaifenesin,DB00874
,34564,DB01098,10035664,210,7939,236,6973,0.010698261,0.781574114,0.643993556,0.948015921,0.037568482,DB0109810035664_,3.281589827,-0.246445298,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,rosuvastatin,DB01098
,34566,DB09401,10035664,32,728,43,717,0.236117256,0.733093936,0.443463788,1.200993768,0.393362957,DB0940110035664_,0.933022537,-0.310481432,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,isosorbide,DB09401
,34567,DB13867,10035664,227,4323,127,2427,1,1.00347481,0.799264898,1.264262326,1,DB1386710035664_,0,0.003468787,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,fluticasone,DB13867
,34569,DB00338,10044390,107,33567,73,22199,0.878832145,0.969335865,0.712842111,1.324454203,0.949052042,DB0033810044390_,0.052291643,-0.031144118,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,34575,DB01098,10044390,36,8113,22,7187,0.188303892,1.449554308,0.82909398,2.589212972,0.334396365,DB0109810044390_,1.095428269,0.371256136,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,34583,DB00588,10058467,47,16477,16,8452,0.182632394,1.5067894,0.838465217,2.848716657,0.327231935,DB0058810058467_,1.117086079,0.409981162,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fluticasone propionate,DB00588
,34584,DB00682,10058467,37,19422,21,16343,0.186674417,1.482567932,0.845043801,2.666784009,0.332322184,DB0068210058467_,1.101650346,0.393775673,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,warfarin,DB00682
,34590,DB01409,10058467,53,5978,28,3938,0.364069198,1.246876751,0.773031655,2.051169379,0.533669621,DB0140910058467_,0.627978319,0.220641825,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,tiotropium,DB01409
,34615,DB08931,10000087,276,6301,70,2376,0.003027133,1.486774202,1.134659568,1.969961733,0.01361653,DB0893110000087_,4.296470768,0.396608808,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,34616,DB01240,10006002,52,5699,13,1563,0.879853886,1.097020702,0.587187696,2.20199827,0.949545405,DB0124010006002_,0.05177193,0.092598052,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,epoprostenol,DB01240
,34622,DB08931,10011224,509,6068,156,2290,0.029509204,1.231305868,1.02025592,1.492500357,0.083632478,DB0893110011224_,2.481323341,0.208075288,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,34624,DB01240,10015090,120,5631,52,1524,0.006351236,0.624610274,0.445120266,0.886839125,0.024785427,DB0124010015090_,3.697499425,-0.470627385,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,34626,DB08931,10015090,223,6354,75,2371,0.466606742,1.109487155,0.846549198,1.46764687,0.633314071,DB0893110015090_,0.456788818,0.103897886,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,34628,DB01240,10019303,189,5562,38,1538,0.084491481,1.375250057,0.961460549,2.012908458,0.185853685,DB0124010019303_,1.682795556,0.318635574,NA,10019303,Heart rate increased,10022891,Investigations,Inv,epoprostenol,DB01240
,34630,DB08931,10019303,183,6394,51,2395,0.073394664,1.343969175,0.976726152,1.877847963,0.167180444,DB0893110019303_,1.788681545,0.295627307,NA,10019303,Heart rate increased,10022891,Investigations,Inv,riociguat,DB08931
,34631,DB01240,10020642,83,5668,17,1559,0.32661379,1.34284658,0.787419354,2.421895579,0.495057721,DB0124010020642_,0.703080914,0.294791674,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,epoprostenol,DB01240
,34633,DB08931,10020642,61,6516,12,2434,0.046352273,1.898763328,1.010024885,3.88140728,0.11820223,DB0893110020642_,2.135358306,0.641202794,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,riociguat,DB08931
,34634,DB01240,10022000,142,5609,33,1543,0.456094582,1.183707699,0.801960532,1.793115598,0.623440344,DB0124010022000_,0.472502198,0.16865163,NA,10022000,Influenza,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,34636,DB08931,10022000,135,6442,38,2408,0.141801814,1.327894951,0.917339662,1.962981254,0.272271499,DB0893110022000_,1.300955553,0.283594944,NA,10022000,Influenza,10021881,Infections and infestations,Infec,riociguat,DB08931
,34637,DB01240,10027599,97,5654,8,1568,0.000174675,3.362253571,1.635317206,8.027145953,0.001286267,DB0124010027599_,6.656011371,1.212611455,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,epoprostenol,DB01240
,34639,DB08931,10027599,97,6480,15,2431,0.000579575,2.42569915,1.397099659,4.509552248,0.003492065,DB0893110027599_,5.657261911,0.886119792,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,34642,DB08931,10030095,327,6250,142,2304,0.121719444,0.848946526,0.690811813,1.047318531,0.243874959,DB0893110030095_,1.41109965,-0.163759079,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,34644,DB08931,10033425,398,6179,135,2311,0.365949785,1.102619367,0.899308325,1.358462312,0.535503973,DB0893110033425_,0.624546971,0.097688592,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,riociguat,DB08931
,34645,DB01240,10033557,386,5365,51,1525,5.31895550306867e-08,2.151309435,1.593387988,2.95678018,1.02311559018046e-06,DB0124010033557_,13.79265809,0.766076696,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,epoprostenol,DB01240
,34647,DB08931,10033557,275,6302,40,2406,3.96758929366587e-10,2.624480757,1.871614245,3.767134649,1.18644009765651e-08,DB0893110033557_,18.24972343,0.96488307,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,riociguat,DB08931
,34650,DB08931,10047899,312,6265,120,2326,0.739564069,0.965301537,0.775177326,1.208265188,0.85016024,DB0893110047899_,0.16233043,-0.035314753,NA,10047899,Weight increased,10022891,Investigations,Inv,riociguat,DB08931
,34651,DB01240,10060800,57,5694,10,1566,0.231756314,1.567541756,0.791053275,3.45131562,0.388032023,DB0124010060800_,0.94666741,0.449508632,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,epoprostenol,DB01240
,34653,DB08931,10060800,43,6534,8,2438,0.080942509,2.005457944,0.930293201,4.945256833,0.179959726,DB0893110060800_,1.715022197,0.695872436,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,riociguat,DB08931
,34657,DB00196,10037660,150,4933,215,3070,1.19225456009056e-14,0.434231387,0.348385679,0.540131783,6.94864991396458e-13,DB0019610037660_,27.99505883,-0.834177737,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,34658,DB00319,10037660,75,1317,104,1749,0.815958225,0.957711299,0.695761685,1.313234322,0.90134507,DB0031910037660_,0.103867109,-0.043208904,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,piperacillin,DB00319
,34659,DB00425,10037660,231,12464,151,7333,0.335822097,0.900041741,0.728411306,1.114734216,0.504969369,DB0042510037660_,0.683257507,-0.105314138,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,34660,DB00455,10037660,243,9158,125,4993,0.619324891,1.059881692,0.848233144,1.32959895,0.760112752,DB0045510037660_,0.274288498,0.05815729,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,34661,DB06403,10039163,299,21172,83,6578,0.396351306,1.119239363,0.873402086,1.447573595,0.565971004,DB0640310039163_,0.569212431,0.112649314,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,ambrisentan,DB06403
,34662,DB06605,10028813,696,13377,304,12729,6.24447621221984e-31,2.178498669,1.896893022,2.506409616,1.49214597489271e-28,DB0660510028813_,64.07216727,0.778635956,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,34663,DB06605,10047461,43,14030,18,13015,0.004395553,2.215902205,1.250711556,4.084476662,0.018432853,DB0660510047461_,3.993620737,0.795659636,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,apixaban,DB06605
,34664,DB06605,10061428,245,13828,175,12858,0.00902128,1.30177802,1.066214944,1.592023014,0.03278141,DB0660510061428_,3.417893678,0.263731038,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,apixaban,DB06605
,34667,DB00193,10000060,121,19199,53,8649,0.934539614,1.028505289,0.738023659,1.45009923,0.974970183,DB0019310000060_,0.02534839,0.028106573,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,34668,DB00213,10000060,183,18712,118,13303,0.444998299,1.102572685,0.869037244,1.403232291,0.6130388,DB0021310000060_,0.48932705,0.097646254,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,34669,DB00448,10000060,38,5107,31,3093,0.261529952,0.742441517,0.448799055,1.23675152,0.423138913,DB0044810000060_,0.860054754,-0.297811177,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,lansoprazole,DB00448
,34670,DB00668,10000060,60,10031,18,4285,0.215354879,1.423936213,0.828111645,2.565892297,0.367839765,DB0066810000060_,1.000107856,0.353425018,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,epinephrine,DB00668
,34671,DB00193,10002198,53,19267,20,8682,0.529792935,1.194108814,0.701490708,2.110277358,0.687022734,DB0019310002198_,0.375387896,0.177400145,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,tramadol,DB00193
,34672,DB00193,10010264,419,18901,128,8574,7.06532103238497e-05,1.484899512,1.213296521,1.827483849,0.000591439,DB0019310010264_,7.432951376,0.395347101,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,34673,DB00448,10010264,99,5046,44,3080,0.08250522,1.373314331,0.950603017,2.011938734,0.182564363,DB0044810010264_,1.700652492,0.317227038,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,34678,DB00193,10016766,54,19266,24,8678,1,1.013474249,0.615391836,1.715547847,1,DB0019310016766_,0,0.013384278,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,34679,DB00213,10016766,76,18819,59,13362,0.601005962,0.914614525,0.641860143,1.308746674,0.745334479,DB0021310016766_,0.293922197,-0.089252587,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,34682,DB00193,10017885,120,19200,48,8654,0.504913538,1.126813655,0.799097858,1.611150585,0.665913314,DB0019310017885_,0.406595776,0.119393875,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,34683,DB00213,10017885,252,18643,93,13328,1.7138770140356e-08,1.937117683,1.519625316,2.487102759,3.64328809655687e-07,DB0021310017885_,14.82520905,0.661201138,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,34684,DB00448,10017885,90,5055,62,3062,0.448088138,0.879312701,0.627155799,1.239585488,0.615842965,DB0044810017885_,0.484763275,-0.128614698,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,lansoprazole,DB00448
,34686,DB00213,10033425,481,18414,199,13222,2.43671248880648e-11,1.735530692,1.465902695,2.060896233,8.74986171697791e-10,DB0021310033425_,20.85681303,0.551313241,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,34687,DB00448,10033425,102,5043,46,3078,0.103782857,1.353339215,0.943562855,1.966838038,0.216674534,DB0044810033425_,1.529358894,0.302575031,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,lansoprazole,DB00448
,34688,DB00668,10033425,103,9988,24,4279,0.006190045,1.838542575,1.168069568,3.003143057,0.024264459,DB0066810033425_,3.718742601,0.608973179,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,epinephrine,DB00668
,34689,DB00213,10048959,402,18493,186,13235,7.17399781418076e-07,1.546762106,1.294877924,1.853189401,1.06686581355441e-05,DB0021310048959_,11.44820026,0.436163782,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,34690,DB00448,10048959,86,5059,33,3091,0.022360567,1.59219292,1.051485529,2.462654525,0.067437037,DB0044810048959_,2.696560908,0.465112261,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,34691,DB00668,10048959,90,10001,35,4268,0.695302928,1.097367162,0.733682661,1.674160277,0.816560818,DB0066810048959_,0.202653883,0.092913821,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,34696,DB00126,10000087,148,10023,50,5895,0.000615132,1.740859327,1.253232676,2.453506964,0.003674714,DB0012610000087_,5.606279875,0.554378858,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,34697,DB00177,10000087,76,4724,26,2824,0.013203686,1.747292184,1.103217053,2.849660576,0.044429223,DB0017710000087_,3.113857846,0.558067266,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,valsartan,DB00177
,34699,DB00215,10000087,121,10982,36,5240,0.01260579,1.603693109,1.095533297,2.399834259,0.042828564,DB0021510000087_,3.150550026,0.472309162,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,34701,DB00273,10000087,89,8392,11,2182,0.017452714,2.103544102,1.118235298,4.373478525,0.055531362,DB0027310000087_,2.890807342,0.74362359,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,topiramate,DB00273
,34702,DB00285,10000087,132,10819,29,3689,0.035646608,1.551922981,1.029990975,2.411355189,0.096774178,DB0028510000087_,2.335375079,0.439494795,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,34703,DB00343,10000087,141,8595,35,5060,1.25368985786057e-06,2.371544539,1.625031208,3.545493911,1.75003918820314e-05,DB0034310000087_,10.95328728,0.863541447,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,34704,DB00433,10000087,98,7558,61,5959,0.171769689,1.26664523,0.909045524,1.776957583,0.313126171,DB0043310000087_,1.161149066,0.236371854,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,34705,DB00490,10000087,67,4003,14,1562,0.033442336,1.867243302,1.035479452,3.608894261,0.092233545,DB0049010000087_,2.383431388,0.624463173,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,buspirone,DB00490
,34707,DB00567,10000087,52,4467,17,2064,0.242424101,1.41329946,0.801781958,2.613666958,0.400636121,DB0056710000087_,0.914701693,0.345927014,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,cephalexin,DB00567
,34708,DB00715,10000087,70,4773,20,2267,0.052631286,1.662264491,0.996475509,2.892813537,0.129965158,DB0071510000087_,2.040488877,0.508180824,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,paroxetine,DB00715
,34709,DB00736,10000087,183,10408,59,5494,0.000808578,1.637224185,1.212242876,2.238899182,0.00461681,DB0073610000087_,5.37805133,0.493002238,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,34710,DB00829,10000087,99,7953,30,4424,0.002981451,1.835602967,1.20703535,2.866651802,0.013438644,DB0082910000087_,4.309620866,0.60737302,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,diazepam,DB00829
,34711,DB00874,10000087,44,3291,25,1951,0.900963987,1.043373763,0.622445558,1.785037379,0.956822626,DB0087410000087_,0.044137249,0.042459466,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,guaifenesin,DB00874
,34712,DB00916,10000087,62,5261,18,2413,0.090733475,1.579737298,0.92001982,2.844102046,0.19637938,DB0091610000087_,1.627706877,0.457258566,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,metronidazole,DB00916
,34714,DB00999,10000087,297,21133,88,12151,1.29317769259297e-08,1.940512309,1.523120523,2.493352894,2.83259797081719e-07,DB0099910000087_,15.07690135,0.662952015,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,34716,DB01039,10000087,53,2920,46,3005,0.41881738,1.185678074,0.78087783,1.806185431,0.587847217,DB0103910000087_,0.5312882,0.170314825,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,fenofibrate,DB01039
,34717,DB01069,10000087,97,6603,18,2377,0.007573382,1.93987029,1.161923023,3.417579613,0.028509324,DB0106910000087_,3.557524084,0.66262111,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,promethazine,DB01069
,34719,DB01137,10000087,75,7697,44,5549,0.305079857,1.228839248,0.834487292,1.828857181,0.471887724,DB0113710000087_,0.751014195,0.206070023,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,34720,DB01156,10000087,153,13469,41,6287,0.001408766,1.741826275,1.225137614,2.526004081,0.007296436,DB0115610000087_,4.92036924,0.554934146,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,34722,DB01233,10000087,68,3353,24,1702,0.14727286,1.438119273,0.887529187,2.404613623,0.280126429,DB0123310000087_,1.272514247,0.363336199,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,metoclopramide,DB01233
,34724,DB00126,10013700,142,10029,42,5903,5.70445470909856e-05,1.989926002,1.399154497,2.883431575,0.000494242,DB0012610013700_,7.612484587,0.688097453,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ascorbic acid,DB00126
,34725,DB00215,10013700,305,10798,50,5226,3.4688468557782e-15,2.952110291,2.178871353,4.072843523,2.17870106580955e-13,DB0021510013700_,29.15487735,1.082520267,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,citalopram,DB00215
,34726,DB00268,10013700,97,2878,19,1526,2.45277212653484e-05,2.706461205,1.635693427,4.707195175,0.000237638,DB0026810013700_,8.344763199,0.995641953,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ropinirole,DB00268
,34727,DB00273,10013700,332,8149,42,2151,1.70982501403142e-06,2.086332132,1.504394097,2.959580902,2.31008740651842e-05,DB0027310013700_,10.6756401,0.735407563,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,topiramate,DB00273
,34728,DB00335,10013700,214,8252,73,5392,8.70558342481529e-07,1.915409271,1.458567151,2.539506386,1.2687899102926e-05,DB0033510013700_,11.27486185,0.649931318,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,atenolol,DB00335
,34729,DB00490,10013700,154,3916,22,1554,8.66645448388571e-07,2.777371555,1.761836687,4.57922626,1.26395955257807e-05,DB0049010013700_,11.27867617,1.021504997,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,buspirone,DB00490
,34730,DB00567,10013700,951,3568,141,1940,9.17426585895531e-54,3.666535433,3.041556234,4.445547276,6.26352150915949e-51,DB0056710013700_,115.5970972,1.299247192,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,cephalexin,DB00567
,34731,DB00829,10013700,339,7713,85,4369,1.42396606122382e-12,2.25898767,1.770549192,2.908613981,6.2481175337256e-11,DB0082910013700_,23.4961558,0.814916779,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,diazepam,DB00829
,34733,DB01112,10013700,206,939,29,550,3.18531952343664e-15,4.157872599,2.764183198,6.455233296,2.00782071159549e-13,DB0111210013700_,29.2365563,1.425003549,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,cefuroxime,DB01112
,34735,DB00126,10013710,38,10133,29,5916,0.310194551,0.765054968,0.45895633,1.287696247,0.477634736,DB0012610013710_,0.738908989,-0.267807594,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,34736,DB00177,10013710,36,4764,46,2804,0.000522082,0.460670985,0.288585353,0.730324094,0.003199939,DB0017710013710_,5.744623549,-0.775071189,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,34738,DB00213,10013710,119,18776,154,13267,7.00394748724223e-07,0.54602795,0.425720753,0.698850973,1.04601568012592e-05,DB0021310013710_,11.46793711,-0.605085114,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,34739,DB00215,10013710,134,10969,112,5164,1.30551553634589e-05,0.563306129,0.433990356,0.732210073,0.000137234,DB0021510013710_,8.893819733,-0.573932052,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,34741,DB00273,10013710,116,8365,38,2155,0.227296653,0.786441239,0.539115206,1.170071803,0.3825389,DB0027310013710_,0.960924933,-0.240237271,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,34742,DB00335,10013710,70,8396,68,5397,0.017762011,0.661752199,0.466255332,0.939600368,0.056307599,DB0033510013710_,2.876925783,-0.412864115,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,34743,DB00338,10013710,174,33500,233,22039,1.38107634542065e-12,0.491290992,0.401052028,0.600942631,6.0755802074279e-11,DB0033810013710_,23.52415853,-0.710718676,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,34744,DB00343,10013710,84,8652,80,5015,0.00188853,0.608668282,0.44179597,0.839011539,0.00928458,DB0034310013710_,4.679400284,-0.496481853,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,34745,DB00433,10013710,40,7616,13,6007,0.005062857,2.426685787,1.270111057,4.949769528,0.020665765,DB0043310013710_,3.879276815,0.886526453,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,34746,DB00482,10013710,53,8206,22,3049,0.695887875,0.895133047,0.534100151,1.548357082,0.81696388,DB0048210013710_,0.202160395,-0.110782916,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,34747,DB00490,10013710,46,4024,27,1549,0.088124834,0.655877566,0.397631399,1.101379175,0.192125514,DB0049010013710_,1.649606399,-0.421781144,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,34750,DB00715,10013710,81,4762,59,2228,0.013229439,0.642365237,0.45183215,0.917899318,0.04449025,DB0071510013710_,3.11248521,-0.442598233,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,34751,DB00736,10013710,74,10517,75,5478,6.04128210515943e-05,0.51393213,0.367006552,0.719528172,0.000518853,DB0073610013710_,7.563889074,-0.665664066,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,34752,DB00788,10013710,49,9307,52,5009,0.000754109,0.507158136,0.335667597,0.765335025,0.004352606,DB0078810013710_,5.436980625,-0.678932419,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,34753,DB00863,10013710,53,10620,47,5793,0.020475638,0.61510898,0.406904626,0.932507939,0.06294394,DB0086310013710_,2.765510795,-0.485955823,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,34755,DB00916,10013710,49,5274,92,2339,1.27645502845606e-16,0.236257285,0.162951986,0.338973895,9.43786791082065e-15,DB0091610013710_,32.2940463,-1.442833876,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,34757,DB00999,10013710,80,21350,110,12129,1.9965950381528e-09,0.413174221,0.305553434,0.556629484,5.22714149181738e-08,DB0099910013710_,16.76681618,-0.883885933,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,34759,DB01039,10013710,36,2937,17,3034,0.00820211,2.187323978,1.194126563,4.162491821,0.030405821,DB0103910013710_,3.493121212,0.782678869,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,34760,DB01050,10013710,101,18007,76,9295,0.016741835,0.685972855,0.503806539,0.937395961,0.053724714,DB0105010013710_,2.923882162,-0.376917222,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,34761,DB01069,10013710,57,6643,10,2385,0.035981525,2.046372832,1.03356447,4.502060202,0.097487438,DB0106910013710_,2.328031746,0.716068876,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,34763,DB01136,10013710,67,9817,157,10958,1.72191624305647e-07,0.476383306,0.351911104,0.638904339,2.96790612778618e-06,DB0113610013710_,12.72765386,-0.741532485,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,34764,DB01137,10013710,107,7665,60,5533,0.133540035,1.287279199,0.927910825,1.800256654,0.260683239,DB0113710013710_,1.344449253,0.252530843,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,34765,DB01156,10013710,117,13505,121,6207,9.7691654775514e-10,0.444427553,0.341087766,0.578935971,2.71871375942233e-08,DB0115610013710_,17.42052186,-0.810968223,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,34766,DB01211,10013710,64,1588,35,752,0.511192551,0.865983815,0.55921224,1.360384066,0.67151584,DB0121110013710_,0.398217674,-0.14388906,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,clarithromycin,DB01211
,34767,DB01233,10013710,28,3393,38,1688,6.20011012453416e-05,0.366652457,0.215952349,0.615751862,0.000530156,DB0123310013710_,7.542339622,-1.003340862,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,34775,DB00316,10016338,93,65381,24,36929,0.0003307,2.188689515,1.384785335,3.586748192,0.002186232,DB0031610016338_,6.125575568,0.78330297,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,34777,DB00338,10016338,61,33613,17,22255,0.00106086,2.375707552,1.369278591,4.340089779,0.005786407,DB0033810016338_,5.152243739,0.86529531,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,34799,DB01156,10016338,51,13571,10,6318,0.008615037,2.374227326,1.19086763,5.249013069,0.031608914,DB0115610016338_,3.454316121,0.864672048,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,34811,DB00316,10027940,75,65399,35,36918,0.372938254,1.209612768,0.799461017,1.862565577,0.542627581,DB0031610027940_,0.611332049,0.190300282,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,34813,DB00338,10027940,56,33618,24,22248,0.085962009,1.544159979,0.941195818,2.605957651,0.18827046,DB0033810027940_,1.669875734,0.43448006,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,34832,DB01050,10027940,38,18070,16,9355,0.56646157,1.22951535,0.669029676,2.363265058,0.717822942,DB0105010027940_,0.331532339,0.206620067,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,34834,DB01104,10027940,43,15420,12,7274,0.112824511,1.690312791,0.874999767,3.523489796,0.230319376,DB0110410027940_,1.468288343,0.524913595,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,34838,DB01156,10027940,40,13582,12,6316,0.232031,1.550059568,0.796566684,3.247847886,0.388380605,DB0115610027940_,0.945769479,0.438293361,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,34842,DB00177,10033425,125,4675,40,2810,0.000431491,1.878198704,1.301573933,2.761939998,0.002730316,DB0017710033425_,5.903337815,0.630313182,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,valsartan,DB00177
,34844,DB00268,10033425,102,2873,35,1510,0.035002135,1.531564392,1.02815093,2.329716015,0.095419116,DB0026810033425_,2.34947634,0.426289691,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ropinirole,DB00268
,34845,DB00273,10033425,171,8310,22,2171,0.00112482,2.030470909,1.294624476,3.333942203,0.006067913,DB0027310033425_,5.104740629,0.708267741,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,topiramate,DB00273
,34846,DB00285,10033425,200,10751,51,3667,0.067303839,1.33754037,0.976701259,1.861050063,0.156500478,DB0028510033425_,1.854696214,0.290832383,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,venlafaxine,DB00285
,34847,DB00335,10033425,213,8253,99,5366,0.005832469,1.398855687,1.094145835,1.798447185,0.023144088,DB0033510033425_,3.766015894,0.335654536,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,34848,DB00343,10033425,245,8491,86,5009,2.41326969909277e-05,1.680522574,1.305855557,2.179888604,0.000234242,DB0034310033425_,8.359154836,0.519104801,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,diltiazem,DB00343
,34849,DB00433,10033425,143,7513,78,5942,0.009300754,1.449934808,1.090329827,1.94019043,0.03357878,DB0043310033425_,3.393860954,0.371518596,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,prochlorperazine,DB00433
,34850,DB00482,10033425,273,7986,68,3003,0.002379806,1.509665832,1.149434292,2.005951232,0.01121226,DB0048210033425_,4.490747445,0.411888323,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,34852,DB00567,10033425,86,4433,34,2047,0.488495731,1.167953198,0.773766875,1.798719498,0.652047039,DB0056710033425_,0.427638574,0.155252813,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,cephalexin,DB00567
,34853,DB00715,10033425,106,4737,30,2257,0.011992551,1.683387531,1.109361352,2.624395573,0.041130508,DB0071510033425_,3.191005158,0.520808151,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,paroxetine,DB00715
,34854,DB00736,10033425,260,10331,98,5455,0.004837675,1.400848114,1.103543437,1.7899787,0.019943268,DB0073610033425_,3.914863627,0.337077849,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,34855,DB00788,10033425,298,9058,97,4964,5.20609358408564e-06,1.68356285,1.330748194,2.145213057,6.12954848186746e-05,DB0078810033425_,9.699804375,0.520912292,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,34856,DB00829,10033425,162,7890,58,4396,0.003540039,1.556156451,1.143400755,2.143433328,0.015458082,DB0082910033425_,4.169623318,0.442218967,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,diazepam,DB00829
,34857,DB00874,10033425,59,3276,22,1954,0.063944246,1.599462096,0.961914861,2.750521597,0.150559816,DB0087410033425_,1.893394825,0.469667383,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,guaifenesin,DB00874
,34860,DB01039,10033425,73,2900,42,3009,0.002472865,1.803236804,1.212660429,2.712151334,0.011567764,DB0103910033425_,4.459532991,0.589583274,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,fenofibrate,DB01039
,34861,DB01069,10033425,162,6538,47,2348,0.233114614,1.237816949,0.886265575,1.757570714,0.389678434,DB0106910033425_,0.942433408,0.213349303,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,promethazine,DB01069
,34863,DB01156,10033425,230,13392,70,6258,0.001409437,1.535363826,1.168018571,2.039750763,0.007297752,DB0115610033425_,4.92018889,0.428767373,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,34865,DB01233,10033425,79,3342,23,1703,0.019343933,1.750107731,1.083629817,2.929570689,0.060214978,DB0123310033425_,2.809834149,0.559677346,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,metoclopramide,DB01233
,34866,DB09020,10033425,34,1920,26,1578,0.795507712,1.074760367,0.623117033,1.87359221,0.889310801,DB0902010033425_,0.117308497,0.072097722,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,bisacodyl,DB09020
,34867,DB00199,10037844,141,2569,28,672,0.205124233,1.317134831,0.864385708,2.071441427,0.355289149,DB0019910037844_,1.034823318,0.275458795,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,erythromycin,DB00199
,34868,DB00213,10037844,482,18413,290,13131,0.024129609,1.185263607,1.020671129,1.378330183,0.071545675,DB0021310037844_,2.637419216,0.169965203,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,34869,DB00215,10037844,223,10880,85,5191,0.084779935,1.251669515,0.96848815,1.630222988,0.186394597,DB0021510037844_,1.679889365,0.224478272,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,citalopram,DB00215
,34870,DB00268,10037844,74,2901,28,1517,0.169784338,1.38191738,0.879193526,2.228035297,0.310659659,DB0026810037844_,1.169057311,0.323471941,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ropinirole,DB00268
,34871,DB00433,10037844,256,7400,168,5852,0.066017525,1.205028093,0.984926814,1.477305368,0.154187208,DB0043310037844_,1.869587781,0.18650288,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,prochlorperazine,DB00433
,34872,DB00490,10037844,91,3979,36,1540,0.92040684,0.978333859,0.655039043,1.488856895,0.964788479,DB0049010037844_,0.035846395,-0.021904298,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,buspirone,DB00490
,34874,DB00567,10037844,192,4327,80,2001,0.464100307,1.109846743,0.845839081,1.467351489,0.631313568,DB0056710037844_,0.459952602,0.104221936,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cephalexin,DB00567
,34875,DB00874,10037844,85,3250,64,1912,0.144568419,0.781397661,0.555334947,1.103983107,0.276422558,DB0087410037844_,1.285824577,-0.246671089,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,guaifenesin,DB00874
,34876,DB00916,10037844,197,5126,62,2369,0.009489614,1.468388516,1.093594204,1.994856715,0.03414105,DB0091610037844_,3.377254816,0.384165552,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,metronidazole,DB00916
,34878,DB01036,10037844,42,1459,9,413,0.606477401,1.320808503,0.627107152,3.112165246,0.749365792,DB0103610037844_,0.288528041,0.278244051,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,tolterodine,DB01036
,34879,DB01112,10037844,56,1089,23,556,0.464508695,1.242995561,0.743358483,2.140093918,0.631542494,DB0111210037844_,0.459590048,0.217524242,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cefuroxime,DB01112
,34880,DB01156,10037844,251,13371,104,6224,0.35721084,1.123418579,0.888520212,1.428779756,0.526925582,DB0115610037844_,0.640695952,0.11637634,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,bupropion,DB01156
,34881,DB01233,10037844,104,3317,39,1687,0.126391917,1.356169791,0.925438198,2.02284498,0.250628912,DB0123310037844_,1.383781874,0.304664396,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,metoclopramide,DB01233
,34882,DB09020,10037844,37,1917,39,1565,0.29497112,0.774575143,0.47785282,1.25357707,0.46087621,DB0902010037844_,0.774625798,-0.255440603,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,bisacodyl,DB09020
,34883,DB00177,10042674,47,4753,12,2838,0.006547402,2.3383985,1.218820519,4.850793948,0.025388755,DB0017710042674_,3.67344891,0.849466293,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,34885,DB00213,10042674,174,18721,70,13351,3.65383351492392e-05,1.772666799,1.33450919,2.376437904,0.0003374,DB0021310042674_,7.994240306,0.572485079,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,34886,DB00268,10042674,41,2934,9,1536,0.015781865,2.384525497,1.137754138,5.594911582,0.051304968,DB0026810042674_,2.969967691,0.869000151,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,34887,DB00273,10042674,61,8420,10,2183,0.236916335,1.581430212,0.802420512,3.468235671,0.39426058,DB0027310042674_,0.930743217,0.458329635,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,34889,DB00343,10042674,109,8627,29,5066,8.21272209088428e-05,2.207045497,1.451630291,3.453960188,0.000674282,DB0034310042674_,7.301862054,0.791654742,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,34890,DB00433,10042674,39,7617,24,5996,0.374882572,1.279154434,0.749208818,2.226192687,0.544694089,DB0043310042674_,0.607530947,0.246199261,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,34891,DB00482,10042674,93,8166,16,3055,0.002363204,2.174425518,1.26844457,3.968015748,0.011145027,DB0048210042674_,4.496761851,0.7767645,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,34893,DB00567,10042674,42,4477,11,2070,0.102657095,1.765251711,0.890952596,3.810041075,0.214998744,DB0056710042674_,1.537123093,0.568293293,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,34895,DB00736,10042674,91,10500,23,5530,0.001032332,2.08368424,1.305368977,3.454997605,0.005656041,DB0073610042674_,5.175031157,0.734137596,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,34896,DB00829,10042674,56,7996,10,4444,0.000270941,3.112123761,1.57118778,6.849324694,0.001856295,DB0082910042674_,6.289172499,1.135305375,female,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,34897,DB00863,10042674,102,10571,37,5803,0.032283579,1.513298768,1.028000845,2.271588046,0.089724968,DB0086310042674_,2.4110062,0.414291883,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,34901,DB00999,10042674,185,21245,54,12185,5.35617384790033e-06,1.964890846,1.4426182,2.714750002,6.28373263075475e-05,DB0099910042674_,9.674961293,0.675436695,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,34904,DB01050,10042674,148,17960,38,9333,4.90239277214854e-05,2.023871957,1.407404026,2.974652588,0.000434428,DB0105010042674_,7.741479708,0.705012487,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,34905,DB01069,10042674,63,6637,14,2381,0.118677659,1.614361174,0.892616955,3.126039252,0.239230206,DB0106910042674_,1.430328984,0.47893932,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,34906,DB01104,10042674,111,15352,29,7257,0.003530409,1.80928524,1.191881209,2.827985597,0.015425602,DB0110410042674_,4.171726673,0.592931872,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,34908,DB01136,10042674,98,9786,63,11052,0.000462992,1.756729982,1.265625547,2.453806383,0.002896523,DB0113610042674_,5.844244322,0.563454116,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,34909,DB01137,10042674,72,7700,32,5561,0.021730435,1.624907642,1.055813704,2.551073024,0.066006179,DB0113710042674_,2.718006916,0.485450979,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,34910,DB01156,10042674,58,13564,11,6317,0.004067538,2.455513267,1.27503132,5.191990697,0.017321223,DB0115610042674_,4.055822794,0.89833581,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,34914,DB00126,10061822,62,10109,26,5919,0.183395685,1.396207159,0.868983299,2.302619742,0.328141014,DB0012610061822_,1.114311841,0.333759388,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,34915,DB00177,10061822,45,4755,15,2835,0.05967535,1.788517661,0.976373212,3.460666277,0.142863206,DB0017710061822_,1.945867711,0.581387155,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,34917,DB00213,10061822,103,18792,63,13358,0.385228507,1.162124033,0.840579575,1.617716803,0.555367137,DB0021310061822_,0.588125876,0.150249394,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,34918,DB00215,10061822,84,11019,22,5254,0.011942754,1.820498625,1.126008776,3.062184355,0.041002521,DB0021510061822_,3.194121731,0.599110433,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,34920,DB00273,10061822,77,8404,12,2181,0.113300101,1.665155787,0.898597098,3.368366981,0.231035685,DB0027310061822_,1.465183098,0.509918685,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,34921,DB00285,10061822,110,10841,27,3691,0.139084892,1.387031801,0.902019631,2.202588271,0.268540843,DB0028510061822_,1.314752262,0.327166069,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,34922,DB00343,10061822,61,8675,37,5058,0.834434585,0.96128159,0.62770831,1.490057032,0.914108238,DB0034310061822_,0.089806292,-0.039487895,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,34923,DB00433,10061822,73,7583,37,5983,0.033419198,1.556627585,1.032718423,2.382391099,0.092184239,DB0043310061822_,2.383966111,0.442521677,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,34928,DB00736,10061822,57,10534,19,5534,0.090593794,1.575998236,0.922533196,2.808455505,0.1961659,DB0073610061822_,1.628794547,0.454888872,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,34929,DB00863,10061822,72,10601,17,5823,0.001136916,2.326291071,1.35555452,4.214974889,0.006123108,DB0086310061822_,5.095685521,0.844275184,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,34931,DB00916,10061822,45,5278,14,2417,0.259371981,1.471886347,0.791551298,2.909355065,0.42048292,DB0091610061822_,0.866351418,0.386544807,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,34935,DB01050,10061822,112,17996,48,9323,0.31548478,1.208769839,0.853817084,1.734157696,0.483127032,DB0105010061822_,0.727475653,0.189603181,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,34936,DB01069,10061822,56,6644,16,2379,0.502408209,1.253194639,0.707102469,2.345475835,0.663641378,DB0106910061822_,0.410013369,0.225696002,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,34937,DB01104,10061822,108,15355,50,7236,1,1.017903619,0.720569542,1.455157592,1,DB0110410061822_,0,0.017745237,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,34939,DB01156,10061822,80,13542,19,6309,0.006587477,1.9615587,1.176958334,3.429841591,0.025512058,DB0115610061822_,3.668604089,0.673739412,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,34943,DB00047,10000891,28,9257,42,8476,0.054342544,0.610443155,0.364041285,1.009287336,0.13312771,DB0004710000891_,2.016446384,-0.493570101,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,insulin glargine,DB00047
,34944,DB00169,10000891,56,38635,64,18111,1.68587328766385e-06,0.410179509,0.281227285,0.596777514,2.28359594775802e-05,DB0016910000891_,10.68717409,-0.891160388,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,34946,DB00316,10000891,95,65379,122,36831,1.69739624041332e-09,0.43866969,0.331785306,0.578560009,4.50212514422442e-08,DB0031610000891_,16.9161312,-0.824008565,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,34947,DB00338,10000891,50,33624,72,22200,2.4790428193004e-05,0.458502957,0.312922863,0.667197829,0.000239829,DB0033810000891_,8.335582835,-0.779788538,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,omeprazole,DB00338
,34950,DB00047,10011078,22,9263,48,8470,0.000675375,0.41911377,0.240719712,0.708558091,0.003975419,DB0004710011078_,5.527625104,-0.869612869,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,insulin glargine,DB00047
,34951,DB00169,10011078,48,38643,50,18125,0.000119431,0.450275193,0.296479814,0.683202737,0.000927812,DB0016910011078_,6.982680923,-0.797896342,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,34953,DB00338,10011078,52,33622,73,22199,3.19687020266709e-05,0.470316781,0.32292784,0.6807742,0.000300106,DB0033810011078_,8.111374178,-0.75434881,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,omeprazole,DB00338
,34971,DB00351,10016173,20,646,39,825,0.141730623,0.655094035,0.358300022,1.163756957,0.272164627,DB0035110016173_,1.301348149,-0.422976489,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,megestrol acetate,DB00351
,34972,DB01012,10016173,58,10574,35,8650,0.174457514,1.355593276,0.875241373,2.12721954,0.316708043,DB0101210016173_,1.149774931,0.3042392,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,cinacalcet,DB01012
,34975,DB00316,10020947,56,65418,48,36905,0.040469758,0.658198182,0.43951507,0.988998453,0.106593274,DB0031610020947_,2.238734866,-0.418249205,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,34977,DB01012,10020947,44,10588,47,8638,0.206297783,0.763771015,0.494076427,1.178727665,0.356836623,DB0101210020947_,1.030477241,-0.269487254,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,cinacalcet,DB01012
,34978,DB00047,10021015,30,9255,28,8490,1,0.982864633,0.566898854,1.7087822,1,DB0004710021015_,0,-0.017283877,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,insulin glargine,DB00047
,34988,DB00047,10028334,105,9180,80,8438,0.209648085,1.206399488,0.891913168,1.637108264,0.360749299,DB0004710028334_,1.019572024,0.187640294,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin glargine,DB00047
,34991,DB00258,10028813,54,624,26,717,0.000309704,2.385050863,1.447781257,4.018957986,0.002071778,DB0025810028813_,6.179348083,0.86922045,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,calcium acetate,DB00258
,34992,DB00351,10028813,70,596,58,806,0.008996592,1.631576716,1.116381461,2.392048084,0.032714313,DB0035110028813_,3.419942595,0.489546858,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,megestrol acetate,DB00351
,34993,DB00047,10035598,39,9246,47,8471,0.234008197,0.760249551,0.483657811,1.188955683,0.390822431,DB0004710035598_,0.939501963,-0.274108543,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,34995,DB00338,10035598,198,33476,134,22138,0.866080853,0.977149555,0.78029818,1.226857237,0.939291974,DB0033810035598_,0.062628907,-0.023115563,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,35005,DB00047,10050584,61,9224,37,8481,0.053558833,1.515808397,0.990291341,2.348691286,0.131670633,DB0004710050584_,2.027451681,0.415948892,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,35006,DB00169,10050584,417,38274,125,18050,5.37374542734186e-06,1.573244357,1.284203379,1.938602468,6.3001292844639e-05,DB0016910050584_,9.67235531,0.453139957,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,35013,DB00316,10051379,43,65431,42,36911,0.012642891,0.57758599,0.368541713,0.905659698,0.042919056,DB0031610051379_,3.148439345,-0.548897946,NA,10051379,Systemic inflammatory response syndrome,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,35032,DB00836,10003658,73,5462,58,4017,0.657608959,0.925654132,0.645090004,1.333486928,0.790725137,DB0083610003658_,0.234804859,-0.077254622,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,loperamide,DB00836
,35041,DB00165,10021097,41,2104,28,1338,0.803572297,0.931205186,0.55906368,1.571765774,0.893727033,DB0016510021097_,0.112354883,-0.071275633,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,pyridoxine,DB00165
,35043,DB01015,10021097,158,9729,225,9156,8.28751031961663e-05,0.660883108,0.534661302,0.815291267,0.000679694,DB0101510021097_,7.293867203,-0.414178296,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sulfamethoxazole,DB01015
,35045,DB00165,10053762,52,2093,40,1326,0.38657276,0.823656057,0.531653448,1.284409864,0.556709675,DB0016510053762_,0.585711405,-0.194002242,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,pyridoxine,DB00165
,35046,DB00227,10053762,63,2404,44,1759,0.843434111,1.047653219,0.697872047,1.584781272,0.92064806,DB0022710053762_,0.082677444,0.046552633,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lovastatin,DB00227
,35047,DB00437,10053762,148,6773,246,11300,1,1.003746472,0.811147408,1.238656896,1,DB0043710053762_,0,0.003739472,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,allopurinol,DB00437
,35048,DB00836,10053762,121,5414,108,3967,0.155163118,0.820950607,0.625960154,1.077838548,0.291006961,DB0083610053762_,1.234408093,-0.197292334,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,loperamide,DB00836
,35050,DB00169,10001551,156,38535,108,18067,0.002285906,0.677216852,0.526169033,0.874340105,0.010850571,DB0016910001551_,4.523537597,-0.389763744,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,35051,DB00433,10001551,38,7618,26,5994,0.615660276,1.149940325,0.679367045,1.974922021,0.757016036,DB0043310001551_,0.278370842,0.13971005,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,prochlorperazine,DB00433
,35056,DB01234,10001551,99,31526,182,32706,3.6349040392061e-06,0.564323891,0.437028891,0.725090348,4.47196127641153e-05,DB0123410001551_,10.01509839,-0.572126918,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,dexamethasone,DB01234
,35057,DB00169,10003481,147,38544,95,18080,0.018621304,0.725815306,0.556647061,0.950273084,0.058408232,DB0016910003481_,2.840298444,-0.320459696,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,35058,DB00433,10003481,51,7605,28,5992,0.139630977,1.435069437,0.886779552,2.366664641,0.269301154,DB0043310003481_,1.311924994,0.361213236,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,prochlorperazine,DB00433
,35063,DB01234,10003481,77,31548,124,32764,0.002345269,0.644910005,0.478629301,0.864327417,0.011072367,DB0123410003481_,4.503302712,-0.438644499,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,dexamethasone,DB01234
,35064,DB00169,10005364,75,38616,38,18137,0.687559511,0.926994738,0.619166347,1.408566059,0.811681829,DB0016910005364_,0.208646852,-0.075807389,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,35065,DB00433,10005364,29,7627,30,5990,0.296124387,0.759210553,0.439175925,1.31069776,0.461977595,DB0043310005364_,0.772238886,-0.275476132,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,prochlorperazine,DB00433
,35070,DB00904,10005364,92,22977,79,14377,0.040705729,0.728701283,0.533192803,0.997794922,0.107053889,DB0090410005364_,2.234422937,-0.316491394,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,ondansetron,DB00904
,35071,DB01234,10005364,34,31591,84,32804,1.14290595659053e-05,0.420337936,0.273422543,0.633212998,0.000121921,DB0123410005364_,9.012138973,-0.866696282,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,dexamethasone,DB01234
,35077,DB01234,10022595,24,31601,36,32852,0.196130482,0.693064877,0.395438603,1.19446026,0.344397736,DB0123410022595_,1.06595808,-0.366631667,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,dexamethasone,DB01234
,35078,DB00169,10024690,57,38634,26,18149,1,1.029902899,0.636806233,1.707139965,1,DB0016910024690_,0,0.029464525,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,cholecalciferol,DB00169
,35084,DB00904,10024690,38,23031,37,14419,0.057819991,0.643020039,0.397786917,1.040220663,0.139373512,DB0090410024690_,1.970597813,-0.44157939,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,ondansetron,DB00904
,35085,DB01234,10024690,27,31598,39,32849,0.218057091,0.719723037,0.423580269,1.206388236,0.371231623,DB0123410024690_,0.990929092,-0.328888812,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,dexamethasone,DB01234
,35086,DB00433,10028372,62,7594,70,5950,0.042384736,0.693996621,0.484100742,0.992818116,0.110444235,DB0043310028372_,2.203244547,-0.365288187,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,prochlorperazine,DB00433
,35090,DB00904,10028372,205,22864,139,14317,0.469925017,0.923507073,0.740156123,1.155071585,0.636191654,DB0090410028372_,0.452255418,-0.079576821,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,35091,DB01234,10028372,212,31413,248,32640,0.223627541,0.888230948,0.735437008,1.072006288,0.378070423,DB0123410028372_,0.972674796,-0.118523493,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,35099,DB00762,10037660,41,1122,69,1300,0.063767704,0.68857178,0.452146094,1.037309594,0.150258549,DB0076210037660_,1.89539781,-0.373135711,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,irinotecan,DB00762
,35101,DB00544,10047942,30,2405,28,2625,0.59809275,1.169400971,0.672952579,2.037942604,0.742999711,DB0054410047942_,0.297059623,0.156491627,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,fluorouracil,DB00544
,35113,DB08934,10013968,82,4407,103,6101,0.547903118,1.102123263,0.812178714,1.49153926,0.702450173,DB0893410013968_,0.353180808,0.097238558,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sofosbuvir,DB08934
,35118,DB00230,10003988,543,19131,182,8469,0.001235456,1.320797774,1.112344844,1.573997655,0.006551135,DB0023010003988_,5.028117029,0.278235929,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,35119,DB00455,10003988,222,9179,90,5028,0.016544322,1.351144331,1.050294505,1.750287687,0.053198056,DB0045510003988_,2.933733426,0.300951886,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,35120,DB00804,10003988,86,2914,10,889,0.001981051,2.623310655,1.352074968,5.689301992,0.009651884,DB0080410003988_,4.640602111,0.964437129,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,dicyclomine,DB00804
,35121,DB01373,10003988,645,22075,158,7223,0.00101536,1.335700514,1.118340528,1.603144803,0.00557448,DB0137310003988_,5.189556263,0.289455883,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,35122,DB01409,10003988,111,5920,50,3916,0.028021545,1.468445202,1.039820747,2.098965548,0.080273152,DB0140910003988_,2.522320055,0.384204155,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tiotropium,DB01409
,35123,DB00230,10009033,97,19577,38,8613,0.575456505,1.123034826,0.763695275,1.681686185,0.724887941,DB0023010009033_,0.3217382,0.116034687,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,35124,DB00455,10009033,64,9337,44,5074,0.227127153,0.790472632,0.529270357,1.190004013,0.382327071,DB0045510009033_,0.961478829,-0.235124245,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,35127,DB01373,10009033,130,22590,33,7348,0.235080347,1.281372739,0.867904159,1.940925086,0.392111363,DB0137310009033_,0.936209389,0.247931955,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,35128,DB00804,10013573,115,2885,25,874,0.152615966,1.393420121,0.891213979,2.257322903,0.287608501,DB0080410013573_,1.246155097,0.331761244,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,dicyclomine,DB00804
,35129,DB01409,10013573,228,5803,126,3840,0.121345833,1.197368169,0.955218621,1.506363751,0.243367559,DB0140910013573_,1.413182389,0.180125956,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,tiotropium,DB01409
,35130,DB00230,10020937,457,19217,189,8462,0.489562763,1.064732666,0.894952617,1.270711,0.652924232,DB0023010020937_,0.426294188,0.062723749,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,35131,DB00455,10020937,119,9282,31,5087,0.00013865,2.103708438,1.40451884,3.238019508,0.00105421,DB0045510020937_,6.854963799,0.74370171,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,35132,DB00804,10020937,58,2942,8,891,0.037839279,2.195222348,1.038144186,5.34482608,0.101330085,DB0080410020937_,2.289371922,0.786283339,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,dicyclomine,DB00804
,35133,DB00836,10020937,74,5461,19,4056,1.11059447403852e-05,2.892361331,1.725236949,5.081399458,0.000118787,DB0083610020937_,9.03817617,1.062073238,female,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,35134,DB00999,10020937,293,21137,107,12132,4.3657835915101e-05,1.571691359,1.253891502,1.982304076,0.000394007,DB0099910020937_,7.839141159,0.452152338,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,35135,DB01409,10020937,46,5985,22,3944,0.262863167,1.377825675,0.810710116,2.409027255,0.424642515,DB0140910020937_,0.856507606,0.320506659,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,tiotropium,DB01409
,35136,DB00455,10035664,368,9033,256,4862,0.002338247,0.773766188,0.655279495,0.914692774,0.011050129,DB0045510035664_,4.505313219,-0.256485533,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,loratadine,DB00455
,35137,DB00804,10035664,99,2901,31,868,0.832403055,0.955540267,0.627572775,1.491227168,0.912624426,DB0080410035664_,0.091430845,-0.045478374,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,dicyclomine,DB00804
,35138,DB00836,10035664,232,5303,196,3879,0.147158968,0.865840412,0.709489851,1.057479365,0.279980707,DB0083610035664_,1.27303458,-0.144054669,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,loperamide,DB00836
,35139,DB00230,10047340,106,19568,27,8624,0.010533767,1.730202415,1.124203669,2.749412687,0.037102855,DB0023010047340_,3.294061349,0.548238405,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,pregabalin,DB00230
,35140,DB00455,10047340,54,9347,6,5112,1.5794464665018e-05,4.921158793,2.117996735,14.01203181,0.000162044,DB0045510047340_,8.727640786,1.59354403,female,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,loratadine,DB00455
,35143,DB00999,10047340,101,21329,24,12215,3.55781928852512e-05,2.410030866,1.531184243,3.936869457,0.000329693,DB0099910047340_,8.017350131,0.879639555,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,hydrochlorothiazide,DB00999
,35144,DB01373,10047340,89,22631,11,7370,0.001002998,2.634936356,1.402771575,5.47142472,0.00551775,DB0137310047340_,5.199785131,0.968859028,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,calcium,DB01373
,35148,DB08932,10024774,108,19335,38,6559,0.848802472,0.964124822,0.659751865,1.436260409,0.924645571,DB0893210024774_,0.078344781,-0.036534509,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,35149,DB00390,10037400,118,4027,44,3257,6.36514213289423e-06,2.168775769,1.516870769,3.150117819,7.31240213999672e-05,DB0039010037400_,9.523353635,0.774162847,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,35150,DB00390,10061818,65,4080,50,3251,0.924698952,1.035858182,0.703234257,1.533624733,0.967584075,DB0039010061818_,0.032952959,0.035230244,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,35151,DB08931,10061818,101,6476,23,2423,0.032315045,1.642983586,1.033702388,2.71502686,0.08978394,DB0893110061818_,2.41034916,0.496513849,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,35155,DB01240,10019196,50,5701,7,1569,0.104814321,1.965617104,0.884622113,5.149166395,0.21822134,DB0124010019196_,1.522245408,0.675806244,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,epoprostenol,DB01240
,35161,DB00682,10051077,35,19424,34,16330,0.548327751,0.865444265,0.523952313,1.430970777,0.702781972,DB0068210051077_,0.352708575,-0.144512303,NA,10051077,Post procedural haemorrhage,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,35164,DB01240,10052267,90,5661,21,1555,0.561704327,1.177200678,0.722997759,2.000359323,0.714032538,DB0124010052267_,0.336826746,0.163139313,NA,10052267,Catheter site inflammation,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,35166,DB00682,10052270,96,19363,16,16348,2.43715717706273e-12,5.065502259,2.9638722,9.220368326,1.03074298309081e-10,DB0068210052270_,22.99557104,1.622453295,female,10052270,Catheter site pruritus,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,35167,DB01240,10052270,324,5427,64,1512,0.013184211,1.410363028,1.06865782,1.885659577,0.044386421,DB0124010052270_,3.114821688,0.343847138,NA,10052270,Catheter site pruritus,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,35169,DB00682,10057688,92,19367,20,16344,7.83729353907479e-10,3.881762405,2.373040942,6.65249745,2.2222573967053e-08,DB0068210057688_,17.62215722,1.356289279,female,10057688,Catheter site discharge,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,35170,DB01240,10057688,240,5511,48,1528,0.040597712,1.38624424,1.007448949,1.941765209,0.106844643,DB0124010057688_,2.236379436,0.326598104,NA,10057688,Catheter site discharge,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,35178,DB06228,10007559,147,15765,125,15951,0.161506336,1.189866747,0.930022625,1.524194492,0.299484589,DB0622810007559_,1.205692317,0.173841324,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,35179,DB00559,10022000,230,9429,63,3243,0.119016209,1.255616927,0.943469045,1.691723722,0.239802312,DB0055910022000_,1.427940395,0.227627027,NA,10022000,Influenza,10021881,Infections and infestations,Infec,bosentan,DB00559
,35180,DB00169,10022116,68,38623,20,18155,0.067268424,1.598180631,0.958570568,2.779479039,0.156467085,DB0016910022116_,1.854909612,0.468865877,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,35183,DB00285,10033371,390,10561,84,3634,6.84167611803367e-05,1.597613827,1.254981192,2.0534922,0.000575467,DB0028510033371_,7.460328566,0.468511158,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,35188,DB00169,10049119,50,38641,12,18163,0.039922145,1.958499277,1.02809204,4.041741727,0.105531612,DB0016910049119_,2.248744734,0.672178505,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,35196,DB00338,10069868,79,33595,25,22247,0.000868671,2.092555201,1.319480202,3.426390048,0.004906635,DB0033810069868_,5.317166814,0.738385903,NA,10069868,Device issue,10077536,Product issues,Prod,omeprazole,DB00338
,35198,DB01164,10007554,52,6472,90,7846,0.042110033,0.700457699,0.487212802,0.998037062,0.109916805,DB0116410007554_,2.208031522,-0.356021301,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,calcium chloride,DB01164
,35200,DB01164,10030124,39,6485,34,7902,0.158666533,1.397650131,0.858555399,2.285333563,0.295720756,DB0116410030124_,1.218339663,0.334792349,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,35203,DB01276,10013709,57,1960,45,1466,0.839246847,0.947452599,0.62570361,1.442021188,0.917639858,DB0127610013709_,0.085950276,-0.053978371,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,35204,DB08907,10013709,135,4118,124,3786,1,1.000935986,0.775267667,1.293116375,1,DB0890710013709_,0,0.000935548,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,canagliflozin,DB08907
,35205,DB09539,10013709,26,641,32,648,0.503664213,0.821493928,0.464484769,1.440840969,0.664799329,DB0953910013709_,0.408270044,-0.196630732,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,omega-3-acid ethyl esters,DB09539
,35220,DB01241,10016173,35,908,33,1038,0.459848423,1.212335106,0.72514408,2.03096945,0.62725043,DB0124110016173_,0.466409408,0.192548339,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,gemfibrozil,DB01241
,35222,DB00437,10017955,92,6829,159,11387,0.843917325,0.964812144,0.736726873,1.257391973,0.921022521,DB0043710017955_,0.082270791,-0.035821866,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,35223,DB00480,10017955,116,67312,151,67511,0.037145385,0.770486675,0.599424705,0.988213938,0.099878971,DB0048010017955_,2.303796113,-0.260732918,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,35224,DB01234,10017955,111,31514,108,32780,0.636034788,1.069030322,0.812420067,1.407146597,0.773792526,DB0123410017955_,0.256451496,0.066751997,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,35232,DB00316,10042361,52,65422,70,36883,1.78426539318126e-06,0.418801222,0.286688767,0.608392516,2.39404879325009e-05,DB0031610042361_,10.63993948,-0.870358881,NA,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,35234,DB00437,10042361,16,6905,36,11510,0.38964222,0.740859634,0.383546862,1.370756215,0.559566506,DB0043710042361_,0.580592891,-0.2999441,NA,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,allopurinol,DB00437
,35237,DB01234,10042361,30,31595,37,32851,0.541662404,0.843046146,0.502879335,1.402790024,0.697033856,DB0123410042361_,0.360921296,-0.170733582,NA,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,35240,DB01136,10043554,41,9843,78,11037,0.005669013,0.589420175,0.393252118,0.87195747,0.022620629,DB0113610043554_,3.788892981,-0.52861598,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,carvedilol,DB01136
,35243,DB05259,10033371,381,10889,85,2643,0.513407344,1.087952663,0.854365289,1.398526022,0.673365203,DB0525910033371_,0.395467448,0.084297639,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,35248,DB00108,10020937,174,10020,36,3259,0.012036857,1.571939979,1.090174733,2.323248801,0.041239416,DB0010810020937_,3.188360787,0.452310512,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,35251,DB00108,10033425,146,10048,35,3260,0.11703597,1.353342561,0.928240959,2.021702837,0.236665036,DB0010810033425_,1.441109487,0.302577504,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,natalizumab,DB00108
,35258,DB00381,10040753,306,29054,97,22790,1.8978185053884e-16,2.474414828,1.961710777,3.144661567,1.3752620586947e-14,DB0038110040753_,31.917547,0.906003935,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,amlodipine,DB00381
,35261,DB00169,10000125,43,38648,19,18156,0.892211787,1.06318109,0.606250706,1.93236798,0.955096007,DB0016910000125_,0.045943412,0.061265442,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,35266,DB01060,10019211,368,8219,105,4976,1.44489387379556e-12,2.121764591,1.698490908,2.669355452,6.32456877147648e-11,DB0106010019211_,23.48399417,0.752248097,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,amoxicillin,DB01060
,35267,DB00169,10040984,160,38531,66,18109,0.391844852,1.139348793,0.84971221,1.542617994,0.56170163,DB0016910040984_,0.576784478,0.130456865,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,35272,DB00927,10053762,251,7246,159,4857,0.608558617,1.058151623,0.861044075,1.303361238,0.751160519,DB0092710053762_,0.28613591,0.056523634,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,famotidine,DB00927
,35273,DB01060,10061428,129,8458,84,4997,0.520264135,0.907310808,0.682366731,1.211744167,0.679352123,DB0106010061428_,0.386615695,-0.097270211,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,amoxicillin,DB01060
,35283,DB00193,10003246,153,19167,47,8655,0.021215934,1.469960606,1.052648576,2.086366894,0.064800607,DB0019310003246_,2.736440311,0.385235602,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,35284,DB00656,10003246,66,11947,22,6597,0.043946073,1.65652463,1.007938603,2.82199674,0.11349767,DB0065610003246_,2.175972973,0.504721811,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,35286,DB00051,10010264,587,25144,238,11182,0.237193603,1.096842513,0.940275116,1.282709776,0.394559621,DB0005110010264_,0.92998502,0.09243561,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,35287,DB00316,10010264,1046,64428,376,36577,7.02032445477569e-15,1.579338655,1.40141723,1.782896207,4.23232174985732e-13,DB0031610010264_,28.49085549,0.457006187,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,35288,DB00476,10010264,403,16854,96,6081,0.000209741,1.51453495,1.207029081,1.916289193,0.001499742,DB0047610010264_,6.502462312,0.415108428,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,35289,DB00563,10010264,1068,45578,316,15032,0.095107335,1.114665139,0.980905962,1.269503569,0.203359335,DB0056310010264_,1.592780739,0.108554036,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,35291,DB00476,10011224,253,17004,65,6112,0.014877934,1.399014902,1.059627829,1.869899232,0.04899048,DB0047610011224_,3.016129293,0.335768347,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,35292,DB00656,10011224,214,11799,78,6541,0.001330885,1.520928735,1.166135551,2.000982366,0.006967798,DB0065610011224_,4.966456054,0.419321158,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,35293,DB00193,10013709,901,18419,382,8320,0.323040309,1.065411409,0.941487934,1.207412339,0.491455044,DB0019310013709_,0.710384811,0.063361024,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,35294,DB00656,10013709,585,11428,304,6315,0.408985293,1.063375067,0.920938333,1.229712125,0.57837082,DB0065610013709_,0.547540059,0.061447875,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,35303,DB00476,10016256,2173,15084,720,5457,0.055429783,1.091856338,0.997461929,1.196134608,0.135042344,DB0047610016256_,2.002166887,0.08787931,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,35304,DB00656,10016256,779,11234,309,6310,2.87197268392021e-07,1.416009238,1.234994457,1.62660749,4.70781428106284e-06,DB0065610016256_,12.26628682,0.347842519,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,35308,DB00588,10022086,161,16363,39,8429,8.26393699061129e-06,2.126487221,1.489179257,3.103048844,9.20413490670414e-05,DB0058810022086_,9.293272636,0.754471426,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,35309,DB00722,10022086,233,25170,112,25920,9.17901416279817e-12,2.142303221,1.70163755,2.710313954,3.52476825813221e-10,DB0072210022086_,21.76603624,0.761881522,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,35310,DB00999,10022086,205,21225,63,12176,7.20004921077613e-06,1.866648381,1.399790854,2.519048154,8.14263743704939e-05,DB0099910022086_,9.415811328,0.624144513,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,35311,DB00158,10022094,110,16705,16,8088,4.47436028483536e-07,3.328477801,1.959189066,6.0310062,7.0172171889557e-06,DB0015810022094_,11.86714383,1.202515083,female,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,35317,DB00722,10022094,52,25351,8,26024,2.13766862715731e-09,6.672239684,3.146938967,16.26457589,5.55752866681146e-08,DB0072210022094_,16.70552722,1.897955588,female,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,35321,DB00005,10002556,197,127885,200,42219,8.92756413836613e-28,0.325193227,0.265639051,0.398018732,1.70662562455966e-25,DB0000510002556_,57.03010922,-1.123335729,male,10002556,Ankylosing spondylitis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,35323,DB00178,10019211,68,1369,42,1638,0.00087297,1.936745233,1.289859733,2.937452298,0.004926154,DB0017810019211_,5.313196772,0.661008849,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ramipril,DB00178
,35327,DB00196,10035226,46,5037,43,3242,0.081585069,0.688591976,0.443236849,1.071546136,0.181005575,DB0019610035226_,1.709227448,-0.373106381,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fluconazole,DB00196
,35328,DB00327,10035226,54,6084,62,4200,0.007610935,0.601306129,0.408692039,0.882297073,0.028621866,DB0032710035226_,3.553584314,-0.508651108,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,hydromorphone,DB00327
,35331,DB06724,10035226,91,7838,64,3855,0.031624465,0.69932905,0.501161835,0.980856106,0.0882758,DB0672410035226_,2.42728927,-0.357633904,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,calcium carbonate,DB06724
,35332,DB00193,10061818,133,19187,71,8631,0.254823257,0.842670546,0.626314141,1.141798206,0.415549171,DB0019310061818_,0.878154331,-0.171179208,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,35333,DB00999,10061818,164,21266,110,12129,0.207147457,0.850346581,0.663078448,1.093928915,0.35783852,DB0099910061818_,1.027673456,-0.16211127,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,35334,DB01409,10061818,53,5978,34,3932,1,1.025307444,0.652864237,1.629974012,1,DB0140910061818_,0,0.024992513,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,35342,DB01268,10067946,22,2121,41,3089,0.369855932,0.781512706,0.441971049,1.34751479,0.539492962,DB0126810067946_,0.617125539,-0.246523871,NA,10067946,Renal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sunitinib,DB01268
,35350,DB01327,10037844,26,637,34,723,0.691967923,0.868033732,0.494333393,1.508299085,0.814289475,DB0132710037844_,0.205439356,-0.141524703,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cefazolin,DB01327
,35363,DB01137,10043255,63,7709,54,5539,0.348020496,0.838277698,0.572503651,1.231079516,0.517575752,DB0113710043255_,0.658599383,-0.176405851,NA,10043255,Tendonitis,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,35368,DB00656,10010071,54,11959,19,6600,0.110470094,1.568481411,0.914023476,2.804575295,0.226763484,DB0065610010071_,1.483847723,0.450107897,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,35370,DB00996,10010071,71,38882,90,22335,6.4816598549781e-07,0.453161514,0.3270838,0.62578777,9.74659206453658e-06,DB0099610010071_,11.53859287,-0.791506674,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,35371,DB01224,10010071,86,8022,35,5882,0.00298027,1.801580101,1.20108667,2.754888647,0.01343562,DB0122410010071_,4.309845859,0.588664113,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,35372,DB00996,10033295,313,38640,263,22162,7.12934671153977e-06,0.682622419,0.577017619,0.808004629,8.0738853215348e-05,DB0099610033295_,9.424290646,-0.3818134,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,35388,DB00370,10014387,46,4495,27,3636,0.195296546,1.378069095,0.83695992,2.310182537,0.343403667,DB0037010014387_,1.068848652,0.320683313,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,mirtazapine,DB00370
,35391,DB00370,10021097,70,4471,73,3590,0.127008063,0.769984512,0.545009018,1.08713198,0.251469855,DB0037010021097_,1.380432158,-0.261384879,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,mirtazapine,DB00370
,35397,DB00182,10013709,533,4661,297,2555,0.848101413,0.983740163,0.844892802,1.146939265,0.924068361,DB0018210013709_,0.078969227,-0.016393479,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,35398,DB00182,10069327,102,5092,65,2787,0.368600494,0.858908958,0.620924288,1.195347373,0.538285042,DB0018210069327_,0.619367041,-0.152092349,NA,10069327,Product quality issue,10077536,Product issues,Prod,amphetamine,DB00182
,35403,DB00512,10029155,65,4672,55,5043,0.198616365,1.275629402,0.874985853,1.865589355,0.347416727,DB0051210029155_,1.057230278,0.243439705,NA,10029155,Nephropathy toxic,10038359,Renal and urinary disorders,Renal,vancomycin,DB00512
,35409,DB00526,10012174,57,1541,67,1827,1,1.008637879,0.691081996,1.467912648,1,DB0052610012174_,0,0.008600786,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,oxaliplatin,DB00526
,35410,DB00544,10012174,67,2368,107,2546,0.013316202,0.673290951,0.485946745,0.927325831,0.044724809,DB0054410012174_,3.107226914,-0.395577723,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,fluorouracil,DB00544
,35411,DB00650,10012174,65,2066,85,1929,0.045958876,0.714059305,0.505702768,1.004323455,0.11741547,DB0065010012174_,2.14203661,-0.33678926,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,leucovorin,DB00650
,35412,DB00762,10012174,63,1100,64,1305,0.411795758,1.167752405,0.803489314,1.696662032,0.581281967,DB0076210012174_,0.542519327,0.15508088,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,irinotecan,DB00762
,35431,DB00762,10028813,159,1004,153,1216,0.06008412,1.258528982,0.985722506,1.607275768,0.143632495,DB0076210028813_,1.940497361,0.229943564,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,irinotecan,DB00762
,35433,DB00331,10043521,56,24890,16,20736,6.95217014767159e-05,2.915685658,1.648340414,5.44791385,0.00058364,DB0033110043521_,7.446225611,1.070105009,female,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,35437,DB00722,10043521,49,25354,42,25990,0.403346309,1.19592636,0.775456659,1.851669403,0.573084234,DB0072210043521_,0.556722569,0.178921082,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,35439,DB00904,10043521,56,23013,20,14436,0.033076841,1.756406452,1.037165786,3.091737549,0.091451012,DB0090410043521_,2.391951838,0.563269933,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,35441,DB00762,10047700,130,1033,124,1245,0.084319482,1.263420016,0.966363615,1.65244871,0.185599596,DB0076210047700_,1.684163635,0.233822343,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,irinotecan,DB00762
,35442,DB00175,10020751,91,8040,48,6058,0.047676869,1.428440955,0.994519818,2.074302381,0.120722567,DB0017510020751_,2.114260199,0.356583608,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,pravastatin,DB00175
,35443,DB00230,10020751,226,19448,63,8588,0.00102713,1.584085268,1.191790542,2.131707627,0.005631648,DB0023010020751_,5.179353149,0.460007123,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,pregabalin,DB00230
,35444,DB00254,10020751,60,5875,14,3374,0.001457985,2.461070334,1.356673901,4.77651852,0.007513603,DB0025410020751_,4.891040137,0.900596351,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,doxycycline,DB00254
,35445,DB00273,10020751,98,8383,15,2178,0.060396311,1.697335729,0.977996831,3.154505495,0.144162462,DB0027310020751_,1.936814405,0.529059803,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,topiramate,DB00273
,35446,DB00678,10020751,153,15446,73,10651,0.009693064,1.445229192,1.085353493,1.939340034,0.034718565,DB0067810020751_,3.360480709,0.36826792,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,losartan,DB00678
,35447,DB00695,10020751,235,27814,95,20433,4.26041326852107e-07,1.817212383,1.425032266,2.332906866,6.68966324749559e-06,DB0069510020751_,11.91494702,0.597303669,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,furosemide,DB00695
,35448,DB00736,10020751,113,10478,43,5510,0.075381051,1.381894632,0.963008453,2.0150156,0.170456894,DB0073610020751_,1.769272835,0.32345548,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,esomeprazole,DB00736
,35450,DB01067,10020751,42,4319,25,4798,0.013806021,1.866177914,1.109165087,3.201223083,0.046034663,DB0106710020751_,3.078360615,0.623892443,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,glipizide,DB01067
,35451,DB01098,10020751,81,8068,49,7160,0.034389676,1.466979902,1.014877354,2.139690416,0.094189083,DB0109810020751_,2.362450993,0.383205799,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,rosuvastatin,DB01098
,35452,DB01156,10020751,115,13507,31,6297,0.005571425,1.729419019,1.153063142,2.664469674,0.022306897,DB0115610020751_,3.802859351,0.547785525,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,bupropion,DB01156
,35453,DB01409,10020751,64,5967,30,3936,0.138126412,1.40715965,0.896713783,2.253860494,0.267126715,DB0140910020751_,1.320032145,0.34157324,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,tiotropium,DB01409
,35458,DB00661,10013709,172,3356,57,1538,0.040681252,1.382820242,1.012560702,1.911921189,0.107000221,DB0066110013709_,2.234924379,0.324125067,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,verapamil,DB00661
,35476,DB00126,10061818,105,10066,78,5867,0.106369035,0.784636418,0.578714282,1.067628429,0.220701795,DB0012610061818_,1.510942831,-0.24253483,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,35478,DB00169,10061818,354,38337,206,17969,0.01572631,0.805480959,0.675788184,0.96198889,0.051159165,DB0016910061818_,2.972813624,-0.216315715,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,35479,DB00285,10061818,74,10877,26,3692,0.908182408,0.966075571,0.609435636,1.576598416,0.958977786,DB0028510061818_,0.041887368,-0.034513217,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,35482,DB01104,10061818,110,15353,58,7228,0.506898255,0.892882375,0.643042481,1.250971838,0.667559529,DB0110410061818_,0.404126711,-0.113300426,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,35484,DB06724,10061818,110,7819,33,3886,0.009514784,1.656583921,1.111331087,2.529328012,0.034215213,DB0672410061818_,3.375084924,0.504757603,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,35486,DB08934,10022004,61,4428,53,6151,0.013098128,1.5986851,1.085849484,2.360304722,0.044153163,DB0893410022004_,3.120090702,0.469181479,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,35487,DB08934,10069327,13,4476,38,6166,0.02191253,0.471307675,0.230090519,0.905797879,0.066424964,DB0893410069327_,2.711682332,-0.75224416,NA,10069327,Product quality issue,10077536,Product issues,Prod,sofosbuvir,DB08934
,35488,DB00722,10000060,158,25245,110,25922,0.001754698,1.474863376,1.148246673,1.899962863,0.008731136,DB0072210000060_,4.740859785,0.388565359,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,35490,DB08934,10000060,36,4453,28,6176,0.022256796,1.783056384,1.056318932,3.038774732,0.067217791,DB0893410000060_,2.699817321,0.578328961,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,sofosbuvir,DB08934
,35495,DB08934,10010305,26,4463,44,6160,0.466661044,0.815610484,0.481326488,1.356476328,0.63332226,DB0893410010305_,0.456775887,-0.203818386,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,sofosbuvir,DB08934
,35500,DB00722,10013496,56,25347,41,25991,0.10460116,1.400540652,0.919169822,2.150077008,0.217921822,DB0072210013496_,1.523618896,0.336858342,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,35521,DB08908,10019465,42,10631,18,3261,0.225409624,0.715755907,0.402543245,1.322928813,0.380227304,DB0890810019465_,0.966986037,-0.334416083,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,35522,DB00203,10039710,89,13789,10,8928,1.39460935119684e-10,5.761608243,2.989380633,12.43588832,4.4379306048679e-09,DB0020310039710_,19.23307765,1.751216645,female,10039710,Scleroderma,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,35543,DB00668,10069217,16,10075,36,4267,5.32036199260428e-09,0.188256732,0.09743745,0.348440228,1.27074706929217e-07,DB0066810069217_,15.87849068,-1.669948654,male,10069217,Needle issue,10077536,Product issues,Prod,epinephrine,DB00668
,35546,DB00005,10067482,76,128006,37,42382,0.063517613,0.680086637,0.453296833,1.036645125,0.149810261,DB0000510067482_,1.898385713,-0.385535082,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,35547,DB00559,10061026,78,9581,49,3257,0.001384208,0.541184296,0.372908852,0.791994339,0.007196895,DB0055910061026_,4.934105553,-0.6139954,NA,10061026,Cardiac operation,10042613,Surgical and medical procedures,Surg,bosentan,DB00559
,35548,DB00115,10010264,321,18104,120,10352,6.20293635555053e-05,1.529562993,1.234631556,1.905384069,0.000530311,DB0011510010264_,7.542046531,0.424982069,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,35549,DB00169,10010264,713,37978,231,17944,3.83261560137001e-07,1.458350818,1.254124212,1.700849068,6.08335151461418e-06,DB0016910010264_,12.00995478,0.37730622,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,35550,DB00203,10010264,703,13175,357,8581,0.000161836,1.282536002,1.124136544,1.465177668,0.001203185,DB0020310010264_,6.722782804,0.248839369,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,35551,DB00559,10010264,328,9331,119,3187,0.580957932,0.941414036,0.757887894,1.175748626,0.729405996,DB0055910010264_,0.31552478,-0.06037224,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,35552,DB01115,10010264,81,3519,25,2243,0.001188556,2.064930322,1.300026399,3.386420041,0.006356297,DB0111510010264_,5.058309332,0.725096483,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,35553,DB01592,10010264,135,6141,47,3020,0.046037074,1.412500665,1.003377073,2.018779653,0.117546953,DB0159210010264_,2.140917427,0.345361655,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,35554,DB06228,10010264,152,15760,68,16008,6.19164462524387e-09,2.270421992,1.693328624,3.071098216,1.46092799797608e-07,DB0622810010264_,15.7390238,0.819965714,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,35555,DB00158,10016173,490,16325,208,7896,0.129390847,1.139412904,0.964578397,1.34965776,0.25474989,DB0015810016173_,1.367473037,0.130513133,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,35556,DB01115,10016173,100,3500,50,2218,0.20250151,1.267367636,0.88978145,1.825096888,0.351929134,DB0111510016173_,1.044325448,0.236942022,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,nifedipine,DB01115
,35557,DB01592,10016173,215,6061,104,2963,0.95170504,1.010629689,0.792529232,1.295285007,0.989813911,DB0159210016173_,0.010238322,0.010573591,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,iron,DB01592
,35558,DB01115,10016256,229,3371,111,2157,0.021602312,1.320029765,1.040672676,1.682219709,0.065723338,DB0111510016256_,2.722301199,0.277654286,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,35559,DB00158,10016807,85,16730,35,8069,0.494278716,1.171297501,0.780728728,1.791289988,0.656818711,DB0015810016807_,0.420347234,0.158112109,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,folic acid,DB00158
,35560,DB00264,10016807,269,29338,175,24717,0.008453584,1.295021184,1.065765608,1.576877531,0.03112515,DB0026410016807_,3.469739099,0.258527053,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,35561,DB00338,10016807,262,33412,125,22147,0.002472675,1.389315857,1.117701939,1.734594939,0.011567764,DB0033810016807_,4.459532991,0.328811437,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,35562,DB00563,10016807,56,46590,21,15327,0.598349944,0.877288698,0.522688185,1.525873814,0.743166294,DB0056310016807_,0.296835445,-0.130919153,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,35563,DB01115,10016807,66,3534,16,2252,0.00022637,2.628225679,1.500364577,4.875836529,0.001599068,DB0111510016807_,6.4383341,0.966308972,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,nifedipine,DB01115
,35564,DB00158,10030124,175,16640,88,8016,0.741095312,0.95799376,0.736258419,1.254003585,0.851496712,DB0015810030124_,0.16075964,-0.042914014,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,35565,DB00563,10030124,134,46512,59,15289,0.065991409,0.746567605,0.545393108,1.032666613,0.154137307,DB0056310030124_,1.869911472,-0.292269104,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,35566,DB01115,10030124,78,3522,35,2233,0.09751465,1.412867137,0.933146083,2.177646252,0.207133426,DB0111510030124_,1.574392121,0.34562107,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,35567,DB00563,10035664,732,45914,286,15062,0.014129873,0.839593286,0.730423079,0.967176722,0.046938857,DB0056310035664_,3.058909437,-0.174837687,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,methotrexate,DB00563
,35568,DB01115,10035664,149,3451,106,2162,0.325009997,0.880647503,0.677774024,1.147484971,0.493452002,DB0111510035664_,0.706329685,-0.127097843,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,nifedipine,DB01115
,35569,DB01592,10035664,256,6020,139,2928,0.324385738,0.895791568,0.722216914,1.114713958,0.492860064,DB0159210035664_,0.70752999,-0.110047518,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,iron,DB01592
,35570,DB06228,10035664,423,15489,333,15743,0.00061041,1.291086762,1.113791587,1.497604666,0.003651487,DB0622810035664_,5.612620815,0.255484315,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,35571,DB00169,10048959,834,37857,287,17888,3.08035460813664e-06,1.373109111,1.197846992,1.577580399,3.87773567408389e-05,DB0016910048959_,10.15767407,0.317077593,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,35572,DB00203,10048959,581,13297,236,8702,4.76563081508348e-10,1.611091751,1.379025326,1.886869159,1.40352499691282e-08,DB0020310048959_,18.08169382,0.476912055,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,35573,DB00264,10048959,641,28966,376,24516,1.72434504353329e-08,1.442870498,1.266897235,1.645057786,3.66405897083852e-07,DB0026410048959_,14.81952411,0.366634531,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,35574,DB00421,10048959,276,8627,115,5137,0.001417644,1.429060007,1.142296373,1.797323145,0.007334469,DB0042110048959_,4.915170231,0.35701689,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,35575,DB01115,10048959,106,3494,36,2232,0.000869689,1.880748618,1.272262582,2.837746815,0.004911326,DB0111510048959_,5.316211259,0.631669899,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,35576,DB01373,10048959,514,22206,112,7269,6.4094567100447e-05,1.502212095,1.220072324,1.863084362,0.000544338,DB0137310048959_,7.515940426,0.406938752,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,35577,DB01592,10048959,167,6109,59,3008,0.031286567,1.393662485,1.026257009,1.914920253,0.087549353,DB0159210048959_,2.435552615,0.331935163,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,35589,DB00115,10017412,60,18365,32,10440,0.828468036,1.065889575,0.68241856,1.693192746,0.909828169,DB0011510017412_,0.094499522,0.063809732,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,cyanocobalamin,DB00115
,35590,DB00158,10017412,35,16780,23,8081,0.262290337,0.732832572,0.420621892,1.299957022,0.424055942,DB0015810017412_,0.857889893,-0.310838018,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,folic acid,DB00158
,35591,DB00169,10017412,132,38559,49,18126,0.174725387,1.266310268,0.905415998,1.796579732,0.317087539,DB0016910017412_,1.148577396,0.236107371,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,cholecalciferol,DB00169
,35592,DB00203,10017412,57,13821,20,8918,0.018921288,1.838913379,1.087212941,3.234095744,0.059155048,DB0020310017412_,2.827593352,0.609174842,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,sildenafil,DB00203
,35593,DB00264,10017412,100,29507,66,24826,0.138143153,1.274780314,0.924497873,1.767859768,0.267149263,DB0026410017412_,1.319947738,0.242773861,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,metoprolol,DB00264
,35594,DB00338,10017412,96,33578,57,22215,0.562976228,1.114285471,0.794301804,1.575508007,0.715095568,DB0033810017412_,0.335339083,0.108213367,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,omeprazole,DB00338
,35595,DB00421,10017412,43,8860,11,5241,0.010635175,2.312240711,1.171273806,4.977130233,0.0373799,DB0042110017412_,3.286622149,0.838217059,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,spironolactone,DB00421
,35597,DB00563,10017412,46,46600,16,15332,0.882964924,0.945908173,0.525461679,1.790475361,0.951066996,DB0056310017412_,0.050170771,-0.055609784,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,methotrexate,DB00563
,35598,DB00695,10017412,100,27949,55,20473,0.103057069,1.331832729,0.948560898,1.886988448,0.215582517,DB0069510017412_,1.534411533,0.286555985,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,furosemide,DB00695
,35600,DB01373,10017412,75,22645,24,7357,1,1.015265669,0.633196373,1.683006807,1,DB0137310017412_,0,0.015150321,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,calcium,DB01373
,35602,DB06228,10017412,32,15880,27,16049,0.516741554,1.197789872,0.694845786,2.079219226,0.676405057,DB0622810017412_,0.390963185,0.180478085,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,rivaroxaban,DB06228
,35605,DB00207,10003549,148,8932,102,5353,0.292054282,0.869593743,0.669548404,1.132986428,0.45752879,DB0020710003549_,0.781915467,-0.139729138,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,35608,DB01015,10003549,251,9636,231,9150,0.746839281,1.031782503,0.857451386,1.242001359,0.855814391,DB0101510003549_,0.155701759,0.031287892,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,35629,DB01015,10017577,77,9810,58,9323,0.195312714,1.261663082,0.884598521,1.808057184,0.343420609,DB0101510017577_,1.068799318,0.232430757,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,35631,DB00207,10019211,325,8755,104,5351,3.4592832932685e-09,1.90989828,1.522692809,2.411895,8.61053611397372e-08,DB0020710019211_,16.26769416,0.647049984,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,35633,DB00879,10019211,48,1729,116,3596,0.445754247,0.860645614,0.598520372,1.221236669,0.613581754,DB0087910019211_,0.488441765,-0.150072457,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,emtricitabine,DB00879
,35634,DB01015,10019211,299,9588,157,9224,5.61291422949407e-10,1.83209119,1.501968296,2.241889599,1.63383666137599e-08,DB0101510019211_,17.92974971,0.605458041,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,35636,DB00207,10020937,78,9002,29,5426,0.027199929,1.621151682,1.04466127,2.579593936,0.078449567,DB0020710020937_,2.545299315,0.483136812,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,35639,DB01015,10020937,88,9799,62,9319,0.071727162,1.349803557,0.962982225,1.901948322,0.164279045,DB0101510020937_,1.806188801,0.299959069,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,35649,DB01015,10021015,51,9836,40,9341,0.400967026,1.210821736,0.783901116,1.881819225,0.570793592,DB0101510021015_,0.560727619,0.19129925,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,sulfamethoxazole,DB01015
,35656,DB00207,10028372,38,9042,27,5428,0.522268312,0.8448966,0.501861424,1.44069302,0.680939225,DB0020710028372_,0.384282221,-0.168541026,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,azithromycin,DB00207
,35659,DB01015,10028372,71,9816,54,9327,0.243288317,1.249298702,0.863565382,1.816344673,0.401622447,DB0101510028372_,0.912242818,0.222582356,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfamethoxazole,DB01015
,35667,DB00425,10028411,141,12554,68,7416,0.194965255,1.224839524,0.909373774,1.66346845,0.342947315,DB0042510028411_,1.070178445,0.202809835,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,35672,DB00451,10003041,50,47221,25,15394,0.081998251,0.652003291,0.395642854,1.100274594,0.181707543,DB0045110003041_,1.705356793,-0.42770567,NA,10003041,Application site erythema,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,35673,DB00921,10003041,261,5584,76,4827,6.24124276512554e-19,2.96815901,2.283791443,3.896587323,5.84852285494919e-17,DB0092110003041_,37.37775745,1.087941899,female,10003041,Application site erythema,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,35682,DB01104,10013754,67,15396,55,7231,0.002491229,0.572144747,0.39407584,0.833736729,0.011627968,DB0110410013754_,4.45434201,-0.558363266,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,35683,DB00451,10022004,294,46977,58,15361,0.000302312,1.657427106,1.246238541,2.237821099,0.00202996,DB0045110022004_,6.19973895,0.505266464,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,35685,DB01156,10022004,77,13545,25,6303,0.135077199,1.433234361,0.901444187,2.351759324,0.262786188,DB0115610022004_,1.336414552,0.359933681,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,35686,DB01156,10033371,442,13180,135,6193,1.00730489648246e-05,1.538386594,1.262744745,1.884057938,0.000109319,DB0115610033371_,9.121242331,0.430734201,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,35705,DB00921,10069327,39,5806,42,4861,0.264894768,0.777457283,0.48876613,1.234003607,0.426835855,DB0092110069327_,0.851355754,-0.251726578,NA,10069327,Product quality issue,10077536,Product issues,Prod,buprenorphine,DB00921
,35706,DB01104,10069327,65,15398,36,7250,0.454764605,0.850146562,0.556771098,1.316634992,0.622350583,DB0110410069327_,0.474251706,-0.162346518,NA,10069327,Product quality issue,10077536,Product issues,Prod,sertraline,DB01104
,35708,DB00921,10061822,53,5792,27,4876,0.032699558,1.652443075,1.019196149,2.73675992,0.090612819,DB0092110061822_,2.401159587,0.502254845,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,35711,DB00005,10033307,36,128046,14,42405,0.624015038,0.85160816,0.448168043,1.709378195,0.763942865,DB0000510033307_,0.269262277,-0.160628764,NA,10033307,Overweight,10027433,Metabolism and nutrition disorders,Metab,etanercept,DB00005
,35712,DB00563,10013082,98,46548,26,15322,0.350577832,1.240689832,0.797996683,1.993316885,0.520291263,DB0056310013082_,0.653366503,0.215667541,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,35713,DB00563,10028334,276,46370,89,15259,0.903286841,1.020494421,0.80021279,1.311902835,0.957348417,DB0056310028334_,0.043587882,0.020287237,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,35726,DB13961,10023547,50,9407,52,6362,0.033268983,0.650328196,0.431502176,0.979149042,0.09185664,DB1396110023547_,2.387526181,-0.430278126,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,fish oil,DB13961
,35727,DB00153,10025482,244,7179,85,3354,0.0220722,1.341125714,1.039810302,1.743653179,0.066801124,DB0015310025482_,2.706035368,0.293509346,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,35728,DB01409,10025482,242,5789,89,3877,8.05956936961859e-07,1.820924352,1.417315921,2.356951215,1.18548282529617e-05,DB0140910025482_,11.34277533,0.599344258,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,35729,DB13961,10025482,279,9178,135,6279,0.000962065,1.413850086,1.144106185,1.754088747,0.005337246,DB1396110025482_,5.233045571,0.346316541,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,35734,DB00108,10027374,40,10154,11,3284,0.744929278,1.176053661,0.591351445,2.544314624,0.854389269,DB0010810027374_,0.157368371,0.162164479,NA,10027374,Mental impairment,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,35735,DB00108,10049848,165,10029,61,3234,0.390273081,0.872269055,0.644669101,1.193402219,0.560141482,DB0010810049848_,0.579565881,-0.136657353,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,35742,DB00108,10007882,57,10137,35,3260,0.003352127,0.523795583,0.337271361,0.82380076,0.014789871,DB0010810007882_,4.213812708,-0.64665378,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,natalizumab,DB00108
,35749,DB08908,10025482,278,10395,54,3225,0.001295778,1.597089215,1.18610975,2.185276088,0.006809319,DB0890810025482_,4.989463118,0.468182732,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,35750,DB08908,10047340,52,10621,11,3268,0.298897963,1.454486823,0.748646961,3.095238783,0.464869853,DB0890810047340_,0.765997799,0.374653139,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,dimethyl fumarate,DB08908
,35751,DB01041,10003549,79,2966,84,3034,0.812351534,0.962033961,0.695459921,1.329733309,0.899071824,DB0104110003549_,0.106392355,-0.038705526,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,thalidomide,DB01041
,35755,DB00188,10013709,119,7767,173,8655,0.028559145,0.766517898,0.600506509,0.975727633,0.081515595,DB0018810013709_,2.506960923,-0.265897231,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,35756,DB01041,10013709,54,2991,71,3047,0.175427059,0.774837244,0.531571219,1.123906626,0.317942121,DB0104110013709_,1.145885921,-0.255102279,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,thalidomide,DB01041
,35757,DB01041,10035226,154,2891,238,2880,3.56264831320982e-05,0.644646924,0.519414665,0.798257507,0.000330082,DB0104110035226_,8.01617001,-0.439052516,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,thalidomide,DB01041
,35758,DB00005,10061962,76,128006,22,42397,0.641133735,1.144180742,0.703974813,1.932251747,0.777943746,DB0000510061962_,0.251101063,0.134688872,NA,10061962,Gallbladder operation,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,35767,DB00338,10039227,51,33623,30,22242,0.650845081,1.124594985,0.702499571,1.829416042,0.785304366,DB0033810039227_,0.24168391,0.117422958,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,35769,DB00722,10039227,30,25373,23,26009,0.336614194,1.337030091,0.7507043,2.410932053,0.505667832,DB0072210039227_,0.681875284,0.290450804,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,35771,DB00333,10010305,45,3026,45,3107,0.915821674,1.026769372,0.661769954,1.593077947,0.962360651,DB0033310010305_,0.038366002,0.026417341,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,methadone,DB00333
,35772,DB00425,10010305,164,12531,113,7371,0.21037219,0.853714277,0.666510656,1.096667399,0.36163847,DB0042510010305_,1.017110269,-0.158158711,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,35773,DB00433,10010305,107,7549,89,5931,0.717333989,0.944593543,0.704822118,1.268448635,0.832962701,DB0043310010305_,0.182766414,-0.057000557,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,prochlorperazine,DB00433
,35774,DB00904,10010305,307,22762,194,14262,0.926418989,0.991530504,0.824652605,1.19450113,0.968728294,DB0090410010305_,0.031771104,-0.008505566,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,35776,DB09035,10010305,42,4684,84,6606,0.068997755,0.705187973,0.473972832,1.035305777,0.159515017,DB0903510010305_,1.835617211,-0.349290884,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,nivolumab,DB09035
,35777,DB09140,10010305,56,3685,22,1776,0.466322206,1.226719903,0.734392601,2.117252221,0.633093464,DB0914010010305_,0.457137215,0.204343862,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,oxygen,DB09140
,35779,DB00472,10011906,390,10369,289,4023,2.19325283157126e-15,0.523576901,0.446547757,0.614499343,1.40780587735899e-13,DB0047210011906_,29.59157383,-0.647071362,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,35780,DB00928,10011906,53,782,85,1201,0.857218252,0.95763458,0.658267082,1.38281805,0.931519401,DB0092810011906_,0.070938262,-0.043289015,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,azacitidine,DB00928
,35781,DB09035,10011906,755,3971,1035,5655,0.464540315,1.038839431,0.936479357,1.152011949,0.63156915,DB0903510011906_,0.459547841,0.038104159,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,nivolumab,DB09035
,35783,DB00433,10013573,231,7425,147,5873,0.045757218,1.242942488,1.003396104,1.54357891,0.117014008,DB0043310013573_,2.145461628,0.217481543,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,35784,DB00904,10013573,730,22339,350,14106,2.40753894999635e-05,1.317017952,1.155768813,1.503009685,0.000233772,DB0090410013573_,8.361162998,0.275370054,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,35786,DB09035,10013573,35,4691,50,6640,1,0.990834054,0.623243847,1.559749679,1,DB0903510013573_,0,-0.009208211,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,nivolumab,DB09035
,35789,DB00433,10035598,108,7548,75,5945,0.410941171,1.134147229,0.83522987,1.546843779,0.580262621,DB0043310035598_,0.544274483,0.125881028,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,35791,DB00904,10035598,271,22798,156,14300,0.423684272,1.089653897,0.890486562,1.337048737,0.592495269,DB0090410035598_,0.523412391,0.08586012,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,35793,DB09035,10035598,89,4637,87,6603,0.013590975,1.456637957,1.068992684,1.985476978,0.045456008,DB0903510035598_,3.091010267,0.376131011,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nivolumab,DB09035
,35807,DB08910,10012735,552,16192,397,17091,7.60234461946644e-09,1.467600077,1.285299064,1.676924326,1.75349902158619e-07,DB0891010012735_,15.55648242,0.383628466,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,35808,DB08910,10061024,116,16628,187,17301,0.000211253,0.645438919,0.506977729,0.818848532,0.001508501,DB0891010061024_,6.496639059,-0.4378247,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,pomalidomide,DB08910
,35809,DB00916,10011224,62,5261,24,2407,0.559423632,1.1818827,0.725019392,1.985224537,0.71216613,DB0091610011224_,0.339444066,0.167108676,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metronidazole,DB00916
,35814,DB00005,10005169,80,128002,46,42373,0.003719133,0.575713766,0.395646457,0.8464971,0.016081165,DB0000510005169_,4.13010655,-0.552144676,NA,10005169,Blindness,10015919,Eye disorders,Eye,etanercept,DB00005
,35820,DB00758,10007515,54,8246,100,9974,0.011640871,0.653176538,0.45955856,0.919673275,0.040189175,DB0075810007515_,3.214157586,-0.425907837,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,35821,DB08816,10007515,20,1131,37,1865,0.78297003,0.891357822,0.487602545,1.585095322,0.881820479,DB0881610007515_,0.125766783,-0.115009336,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,ticagrelor,DB08816
,35824,DB00005,10013395,39,128043,20,42399,0.130570857,0.645707497,0.367516057,1.168614883,0.256583057,DB0000510013395_,1.360302857,-0.437408668,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,35828,DB00996,10028836,216,38737,70,22355,1.49780434021669e-05,1.780739055,1.353281981,2.367669756,0.000154847,DB0099610028836_,8.773074617,0.577028478,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,35829,DB00335,10002855,169,8297,55,5410,3.34859411774001e-06,2.00345205,1.466714716,2.773566729,4.1653630201112e-05,DB0033510002855_,10.08612203,0.694871717,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,atenolol,DB00335
,35830,DB00381,10002855,402,28958,161,22726,9.68192650352866e-14,1.959496389,1.626797861,2.36938093,4.98022383845892e-12,DB0038110002855_,26.02554628,0.672687496,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,35831,DB00575,10002855,103,5141,73,3756,0.877688359,1.030842247,0.754001815,1.415389395,0.948135727,DB0057510002855_,0.053257615,0.030376183,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,clonidine,DB00575
,35834,DB00381,10005734,134,29226,92,22795,0.382510395,1.135994762,0.864239219,1.498753067,0.552600277,DB0038110005734_,0.593120366,0.127508709,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,amlodipine,DB00381
,35836,DB00641,10005734,50,14074,59,12416,0.148926448,0.747634628,0.502059208,1.10947843,0.282500391,DB0064110005734_,1.264075343,-0.290840886,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,simvastatin,DB00641
,35841,DB00575,10047700,190,5054,131,3698,0.645404223,1.061245983,0.8414198,1.341774982,0.78115992,DB0057510047700_,0.246975386,0.059443674,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,clonidine,DB00575
,35846,DB00924,10003549,249,9913,98,4153,0.633875664,1.064456665,0.836803034,1.36275767,0.772335433,DB0092410003549_,0.258336324,0.062464495,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,35853,DB00404,10020642,193,19699,83,9779,0.304043994,1.154312154,0.886911438,1.513391918,0.470631669,DB0040410020642_,0.75367951,0.143504629,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,35855,DB00836,10020642,39,5496,36,4039,0.348939253,0.79616463,0.492065927,1.291460427,0.518448266,DB0083610020642_,0.656915032,-0.227949293,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,loperamide,DB00836
,35856,DB00924,10020642,120,10042,32,4219,0.024972203,1.575477725,1.057150743,2.409651213,0.073413976,DB0092410020642_,2.611640957,0.454558544,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,cyclobenzaprine,DB00924
,35858,DB00316,10025482,1764,63710,672,36281,2.4253246371694e-19,1.494855442,1.365662852,1.637721787,2.37871858537305e-17,DB0031610025482_,38.27738465,0.402029508,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,35860,DB00836,10025482,148,5387,56,4019,1.08272139520684e-05,1.971570715,1.436178894,2.739575577,0.000116232,DB0083610025482_,9.059924941,0.678830542,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,35861,DB00924,10025482,350,9812,83,4168,7.69632280374082e-07,1.791202125,1.402129877,2.310308718,1.13650474660858e-05,DB0092410025482_,11.38496792,0.582886973,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,35864,DB00924,10062355,66,10096,21,4230,0.291057528,1.316727636,0.794210066,2.269107895,0.456456974,DB0092410062355_,0.784260835,0.275149595,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,35868,DB00005,10061226,146,127936,37,42382,0.170612174,1.307178421,0.905810719,1.929803295,0.311686197,DB0000510061226_,1.165758378,0.267870938,NA,10061226,Limb operation,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,35872,DB01240,10037423,102,5649,35,1541,0.248608041,0.795019384,0.53424525,1.208149603,0.40797018,DB0124010037423_,0.896561196,-0.229388782,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,35876,DB00203,10022000,306,13572,118,8820,9.96453694101607e-07,1.685210365,1.355959116,2.105820091,1.42656782949133e-05,DB0020310022000_,11.15765402,0.521890402,NA,10022000,Influenza,10021881,Infections and infestations,Infec,sildenafil,DB00203
,35877,DB00559,10007598,70,9589,19,3287,0.395918462,1.262873045,0.750535665,2.224713307,0.565551697,DB0055910007598_,0.569953569,0.23338932,NA,10007598,Cardiac pacemaker insertion,10042613,Surgical and medical procedures,Surg,bosentan,DB00559
,35878,DB00559,10048561,33,9626,22,3284,0.019061093,0.511742606,0.289103858,0.922833603,0.059496595,DB0055910048561_,2.821836195,-0.669933503,NA,10048561,Stent placement,10042613,Surgical and medical procedures,Surg,bosentan,DB00559
,35881,DB00512,10070863,102,4635,123,4975,0.418165981,0.89011004,0.675647539,1.170548457,0.587189498,DB0051210070863_,0.532407686,-0.116410183,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,vancomycin,DB00512
,35894,DB01012,10000087,160,10472,120,8565,0.505814763,1.090553295,0.853719735,1.396019545,0.666681395,DB0101210000087_,0.405443016,0.086685177,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,cinacalcet,DB01012
,35895,DB06643,10008190,135,52286,27,7488,0.121461859,0.716068415,0.470652312,1.127214486,0.243525931,DB0664310008190_,1.412531847,-0.333979565,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,35896,DB00557,10022061,43,5944,10,3057,0.019748672,2.211323987,1.092278333,4.942514962,0.061185035,DB0055710022061_,2.79385265,0.793591425,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,35897,DB00588,10022061,100,16424,20,8448,3.94532575589801e-05,2.571760087,1.578566904,4.393141054,0.00036033,DB0058810022061_,7.928491114,0.944590523,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,35899,DB00341,10022093,70,11335,8,5060,3.41845700827287e-05,3.906210838,1.875093118,9.406644646,0.000318146,DB0034110022093_,8.053000271,1.362567809,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,35901,DB00588,10022093,70,16454,9,8459,6.82857633344462e-06,3.998132898,1.989011016,9.1118424,7.77624618946695e-05,DB0058810022093_,9.461851738,1.385827477,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,35905,DB00588,10024570,51,16473,13,8455,0.023873895,2.013524407,1.078620472,4.038088518,0.070934871,DB0058810024570_,2.64599313,0.699886623,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,35907,DB00341,10043528,47,11358,13,5055,0.160261788,1.609023756,0.855500667,3.244695124,0.29783866,DB0034110043528_,1.211203347,0.475627632,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,35909,DB00588,10043528,42,16482,15,8453,0.263369639,1.435995452,0.779659028,2.789483988,0.425199371,DB0058810043528_,0.855197112,0.361858304,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,35916,DB00335,10005750,113,8353,62,5403,0.312169256,1.1788564,0.855600952,1.637224056,0.479675772,DB0033510005750_,0.734644879,0.164544816,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,atenolol,DB00335
,35917,DB00381,10005750,459,28901,265,22622,8.53819054989268e-05,1.355757165,1.161726125,1.584680132,0.000697301,DB0038110005750_,7.268293337,0.304360092,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,amlodipine,DB00381
,35918,DB00482,10005750,59,8200,19,3052,0.701405693,1.155745534,0.677954325,2.05655156,0.820684206,DB0048210005750_,0.197616889,0.14474562,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,celecoxib,DB00482
,35920,DB01275,10005750,64,3915,45,3304,0.383838354,1.200230662,0.804548932,1.803802512,0.553833844,DB0127510005750_,0.590890558,0.182513757,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,hydralazine,DB01275
,35921,DB01029,10013968,82,1258,40,861,0.088201662,1.402854337,0.939727423,2.123484639,0.192261254,DB0102910013968_,1.648900133,0.338508973,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,irbesartan,DB01029
,35922,DB00335,10013971,34,8432,23,5442,0.892265889,0.95409219,0.545195294,1.698283334,0.955096839,DB0033510013971_,0.045942542,-0.046994977,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atenolol,DB00335
,35924,DB00722,10013971,109,25294,92,25940,0.179480134,1.215034794,0.911617052,1.622480199,0.323225358,DB0072210013971_,1.129405497,0.194772713,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,35928,DB00381,10049414,66,29294,93,22794,0.000215215,0.552224065,0.396368109,0.765589205,0.001532835,DB0038110049414_,6.480636086,-0.5938014,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,35930,DB00695,10049414,106,27943,76,20452,0.940122149,1.020834731,0.752764958,1.390000418,0.979472459,DB0069510049414_,0.020741159,0.020620657,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,35931,DB00722,10049414,61,25342,70,25962,0.541002898,0.892750674,0.622477777,1.277352274,0.696388893,DB0072210049414_,0.361847021,-0.113447937,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,35935,DB00381,10051128,47,29313,32,22855,0.572723455,1.145142597,0.715178336,1.855212447,0.722744059,DB0038110051128_,0.324700118,0.135529168,NA,10051128,Blood pressure inadequately controlled,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,35944,DB00695,10051301,31,28018,19,20509,0.570149995,1.194291073,0.653494678,2.238219954,0.720856239,DB0069510051301_,0.327315553,0.177552765,NA,10051301,Exercise tolerance decreased,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,35949,DB00451,10033661,146,47125,87,15332,1.68590429235132e-05,0.546006134,0.415583011,0.720905416,0.000171826,DB0045110033661_,8.669026666,-0.605125068,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,levothyroxine,DB00451
,35950,DB00497,10033661,84,19183,101,16274,0.021613633,0.705576018,0.521470839,0.95261848,0.065751081,DB0049710033661_,2.721879168,-0.348740763,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,oxycodone,DB00497
,35951,DB06724,10033661,49,7880,31,3888,0.284661908,0.779933338,0.486587277,1.267452463,0.4492193,DB0672410033661_,0.800244092,-0.248546828,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,calcium carbonate,DB06724
,35952,DB00186,10035669,40,16861,64,9944,6.33805851963583e-07,0.368615325,0.24170593,0.556190647,9.55799588001306e-06,DB0018610035669_,11.55813249,-0.998001659,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,lorazepam,DB00186
,35953,DB00451,10035669,67,47204,57,15362,2.90648392214476e-07,0.382539833,0.264529424,0.554731946,4.76141663406513e-06,DB0045110035669_,12.25496532,-0.960922493,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,35954,DB00480,10035669,23,67405,36,67626,0.117429776,0.640989275,0.362599049,1.111792392,0.237305443,DB0048010035669_,1.43840718,-0.444742555,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,35955,DB00497,10035669,90,19177,61,16314,0.190427388,1.25513159,0.896192315,1.768201365,0.337121264,DB0049710035669_,1.087312579,0.227240419,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,oxycodone,DB00497
,35964,DB00005,10075203,45,128037,7,42412,0.075651192,2.129307643,0.953163285,5.597187545,0.17087665,DB0000510075203_,1.76681333,0.755796877,NA,10075203,Mouth swelling,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,35965,DB08904,10003988,119,11491,27,3532,0.169790983,1.354669502,0.884356244,2.144508702,0.310661004,DB0890410003988_,1.169052982,0.303557514,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,certolizumab pegol,DB08904
,35966,DB00563,10006002,72,46574,33,15315,0.114079423,0.717455,0.468748027,1.119070042,0.232271184,DB0056310006002_,1.459849692,-0.332045052,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,35967,DB00051,10016322,186,25545,79,11341,0.789408206,1.045267075,0.798392498,1.379257921,0.885855574,DB0005110016322_,0.12120135,0.044272427,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,35968,DB08904,10016322,59,11551,15,3544,0.58395753,1.206780757,0.674922132,2.293485722,0.731896037,DB0890410016322_,0.312116802,0.187956283,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,35970,DB00563,10022000,362,46284,83,15265,0.002396301,1.438417999,1.129470152,1.850149202,0.011275829,DB0056310022000_,4.485093875,0.363543898,NA,10022000,Influenza,10021881,Infections and infestations,Infec,methotrexate,DB00563
,35971,DB00051,10027599,186,25545,31,11389,2.1960895562165e-08,2.674985568,1.820494377,4.052329617,4.56317897115817e-07,DB0005110027599_,14.60007613,0.983943985,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,35972,DB08904,10027599,74,11536,6,3553,0.000288339,3.798425689,1.662652274,10.6900268,0.001952846,DB0890410027599_,6.23846751,1.334586688,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,certolizumab pegol,DB08904
,35973,DB08904,10033371,501,11109,129,3430,0.075511683,1.199113268,0.982280224,1.472265482,0.170654486,DB0890410033371_,1.768114314,0.18158234,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,35974,DB08904,10046571,251,11359,14,3545,9.68408659100282e-16,5.594964478,3.266948312,10.39643724,6.46056385899769e-14,DB0890410046571_,30.3704747,1.721866993,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,35976,DB00563,10061520,100,46546,21,15327,0.058293689,1.567977697,0.971948327,2.644710922,0.140277362,DB0056310061520_,1.964133661,0.449786698,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,35981,DB00668,10009033,57,10034,14,4289,0.068352755,1.740259432,0.956128356,3.385583289,0.158323243,DB0066810009033_,1.843116492,0.554034201,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,35982,DB09153,10009033,58,7741,32,5667,0.23871173,1.326859565,0.846169071,2.114641984,0.396420131,DB0915310009033_,0.925280694,0.282814921,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,35983,DB00275,10013968,70,1990,37,1200,0.544387725,1.140823869,0.750055777,1.759910679,0.699407037,DB0027510013968_,0.357522393,0.131750694,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,olmesartan,DB00275
,35984,DB00668,10013968,321,9770,156,4147,0.185943773,0.873431713,0.71650421,1.068203418,0.331391808,DB0066810013968_,1.104453892,-0.135325329,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,35985,DB00005,10044390,85,127997,31,42388,0.667406721,0.908020056,0.595353906,1.418048851,0.797997846,DB0000510044390_,0.22564938,-0.096488813,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,35991,DB00557,10042772,41,5946,21,3046,1,1.000166241,0.576297153,1.784866343,1,DB0055710042772_,0,0.000166227,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,35993,DB00099,10029366,37,2348,31,1924,1,0.978017543,0.587947865,1.636843639,1,DB0009910029366_,0,-0.022227671,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,filgrastim,DB00099
,35996,DB00099,10046571,48,2337,11,1944,2.9451266646558e-05,3.628804739,1.85203523,7.769879856,0.000279115,DB0009910046571_,8.183885265,1.288903321,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,filgrastim,DB00099
,36005,DB00448,10006451,60,5085,25,3099,0.116362793,1.462590665,0.901057224,2.439889947,0.235675452,DB0044810006451_,1.445299623,0.380209291,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,lansoprazole,DB00448
,36006,DB09153,10006451,131,7668,55,5644,0.000416891,1.753050905,1.267543101,2.452769461,0.002651017,DB0915310006451_,5.932811902,0.561357644,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,36013,DB06403,10007882,142,21329,28,6633,0.029392318,1.57707627,1.044825067,2.46015397,0.083350639,DB0640310007882_,2.484699002,0.455572671,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,36017,DB00727,10011078,39,3804,62,4111,0.070750098,0.67983267,0.442229142,1.03380429,0.162606556,DB0072710011078_,1.816421762,-0.385908585,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,nitroglycerin,DB00727
,36018,DB00727,10028596,130,3713,159,4014,0.308750309,0.883904834,0.692524638,1.126600293,0.47606628,DB0072710028596_,0.742198191,-0.123405876,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,nitroglycerin,DB00727
,36019,DB01275,10008190,64,3915,51,3298,0.778196325,1.057137316,0.718018223,1.563318244,0.879072925,DB0127510008190_,0.128887421,0.055564609,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,hydralazine,DB01275
,36020,DB08901,10011906,67,440,91,489,0.262854996,0.818408481,0.572319302,1.165912895,0.424642364,DB0890110011906_,0.856507962,-0.200393702,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ponatinib,DB08901
,36023,DB00065,10004146,33,9431,40,4917,0.00044859,0.430149246,0.262474885,0.700524009,0.002820858,DB0006510004146_,5.870714337,-0.843623048,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,infliximab,DB00065
,36024,DB00316,10004146,51,65423,64,36889,2.32246641478656e-05,0.449318475,0.304710675,0.659588565,0.000226979,DB0031610004146_,8.390652603,-0.800023344,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,36025,DB00451,10004146,53,47218,34,15385,0.002639513,0.507890474,0.323944636,0.80615767,0.012180405,DB0045110004146_,4.407926743,-0.677489456,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levothyroxine,DB00451
,36029,DB00065,10041823,32,9432,30,4927,0.022717409,0.557194447,0.327510442,0.950464161,0.068235773,DB0006510041823_,2.684786317,-0.584841002,NA,10041823,Squamous cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,infliximab,DB00065
,36031,DB00451,10041823,37,47234,20,15399,0.088686916,0.603133828,0.34100017,1.097089419,0.193080951,DB0045110041823_,1.644645743,-0.50561617,NA,10041823,Squamous cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levothyroxine,DB00451
,36037,DB00343,10003239,224,8512,67,5028,4.00557405904212e-07,1.974771721,1.493287919,2.641073186,6.33111931099953e-06,DB0034310003239_,11.97003351,0.680452807,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,diltiazem,DB00343
,36038,DB00682,10003239,398,19061,215,16149,9.54185210635139e-08,1.56833197,1.323457063,1.862639021,1.73329359098442e-06,DB0068210003239_,13.26548715,0.450012615,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,36040,DB00204,10003658,105,859,83,960,0.026143651,1.413547333,1.033826251,1.937660637,0.076056516,DB0020410003658_,2.576278585,0.346102384,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,dofetilide,DB00204
,36041,DB00343,10003658,360,8376,273,4822,0.000987703,0.759188619,0.644236447,0.895408222,0.005449027,DB0034310003658_,5.212318269,-0.275505023,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,diltiazem,DB00343
,36044,DB00264,10005169,45,29562,32,24860,0.493956289,1.1825739,0.734854368,1.923308158,0.656651463,DB0026410005169_,0.420601899,0.167693334,NA,10005169,Blindness,10015919,Eye disorders,Eye,metoprolol,DB00264
,36046,DB00451,10005169,93,47178,28,15391,0.752455091,1.083556379,0.703253209,1.718429036,0.860523932,DB0045110005169_,0.150213851,0.080248575,NA,10005169,Blindness,10015919,Eye disorders,Eye,levothyroxine,DB00451
,36047,DB00641,10005169,35,14089,18,12457,0.072513808,1.719169802,0.947098746,3.226153402,0.165690916,DB0064110005169_,1.797631179,0.541841501,NA,10005169,Blindness,10015919,Eye disorders,Eye,simvastatin,DB00641
,36048,DB00722,10005169,45,25358,26,26006,0.023368522,1.774965736,1.071436312,2.998061254,0.06972491,DB0072210005169_,2.66319763,0.573781119,NA,10005169,Blindness,10015919,Eye disorders,Eye,lisinopril,DB00722
,36065,DB00722,10005760,30,25373,30,26002,1,1.024794451,0.596678497,1.7601316,1,DB0072210005760_,0,0.024492057,NA,10005760,Blood pressure systolic increased,10022891,Investigations,Inv,lisinopril,DB00722
,36069,DB00343,10007739,38,8698,19,5076,0.680224572,1.16718263,0.655554575,2.145831642,0.806591008,DB0034310007739_,0.214938544,0.154592836,NA,10007739,Cataract,10015919,Eye disorders,Eye,diltiazem,DB00343
,36070,DB00641,10007739,84,14040,48,12427,0.017924582,1.54891951,1.072886166,2.258593886,0.056696038,DB0064110007739_,2.87005094,0.437557597,NA,10007739,Cataract,10015919,Eye disorders,Eye,simvastatin,DB00641
,36071,DB00722,10007739,122,25281,69,25963,6.11576059206345e-05,1.815780735,1.339991406,2.477419174,0.000524051,DB0072210007739_,7.553920786,0.596515532,NA,10007739,Cataract,10015919,Eye disorders,Eye,lisinopril,DB00722
,36072,DB00199,10013709,56,2654,21,679,0.152702014,0.682325921,0.40332602,1.195115191,0.287726234,DB0019910013709_,1.245745829,-0.382247846,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,erythromycin,DB00199
,36073,DB00343,10013709,248,8488,153,4942,0.599424455,0.943755878,0.765985148,1.1657685,0.744067365,DB0034310013709_,0.295623703,-0.05788775,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,36089,DB00199,10016256,66,2644,19,681,0.683348192,0.894709249,0.526150489,1.589946,0.808568573,DB0019910016256_,0.212489788,-0.111256475,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,erythromycin,DB00199
,36092,DB00343,10017577,119,8617,47,5048,0.023231534,1.483202871,1.047744249,2.129738133,0.069422563,DB0034310017577_,2.667543348,0.394203852,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,36093,DB00641,10017577,234,13890,164,12311,0.022733185,1.264615994,1.029782604,1.555965543,0.068267081,DB0064110017577_,2.684327599,0.234768514,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,36112,DB00343,10019301,35,8701,15,5080,0.378835941,1.362266297,0.724094751,2.687632477,0.548800061,DB0034310019301_,0.600021092,0.309149708,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,diltiazem,DB00343
,36113,DB00451,10019301,95,47176,40,15379,0.192849807,0.774234547,0.529547196,1.150691617,0.340216596,DB0045110019301_,1.078172819,-0.255880419,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,36115,DB00682,10019301,68,19391,32,16332,0.006428845,1.789740834,1.158755088,2.817670238,0.025014017,DB0068210019301_,3.688318942,0.582070824,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,warfarin,DB00682
,36116,DB00722,10019301,43,25360,53,25979,0.413966781,0.831127936,0.542408475,1.267112878,0.583267307,DB0072210019301_,0.539109696,-0.184971541,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,lisinopril,DB00722
,36117,DB01373,10019301,37,22683,14,7367,0.626032773,0.858378586,0.452923676,1.719838012,0.765592921,DB0137310019301_,0.267104685,-0.152710035,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,calcium,DB01373
,36120,DB00264,10019303,275,29332,143,24749,2.03810844339692e-06,1.622585796,1.319968342,2.001601631,2.6940749527125e-05,DB0026410019303_,10.52187057,0.484021047,NA,10019303,Heart rate increased,10022891,Investigations,Inv,metoprolol,DB00264
,36121,DB00343,10019303,151,8585,52,5043,0.00071915,1.705714986,1.234341439,2.389613819,0.004187608,DB0034310019303_,5.475625649,0.533984369,NA,10019303,Heart rate increased,10022891,Investigations,Inv,diltiazem,DB00343
,36126,DB00451,10020850,96,47175,17,15402,0.016137949,1.843585942,1.093155979,3.296256914,0.052172884,DB0045110020850_,2.953192389,0.611712556,NA,10020850,Hyperthyroidism,10014698,Endocrine disorders,Endo,levothyroxine,DB00451
,36134,DB00451,10023547,185,47086,62,15357,0.882294966,0.973182326,0.725816477,1.320200828,0.950859822,DB0045110023547_,0.050388628,-0.027183829,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,levothyroxine,DB00451
,36135,DB00641,10023547,62,14062,60,12415,0.64976883,0.912308577,0.62873917,1.324557073,0.784509942,DB0064110023547_,0.242696033,-0.091776995,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,simvastatin,DB00641
,36136,DB00682,10023547,76,19383,71,16293,0.561643993,0.899781197,0.642025001,1.262413403,0.714024443,DB0068210023547_,0.336838084,-0.105603659,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,warfarin,DB00682
,36137,DB00722,10023547,101,25302,102,25930,0.943988724,1.014774384,0.762545777,1.350283689,0.982722423,DB0072210023547_,0.017428576,0.014666306,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,lisinopril,DB00722
,36138,DB01373,10023547,131,22589,65,7316,0.005919376,0.652742114,0.480632502,0.893982567,0.023418244,DB0137310023547_,3.754239915,-0.426573152,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,calcium,DB01373
,36175,DB00316,10008469,455,65019,208,36745,0.011840023,1.23628859,1.046399999,1.464459974,0.040742948,DB0031610008469_,3.20047251,0.212113818,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,36176,DB00476,10008469,89,17168,23,6154,0.196450222,1.38702633,0.868082675,2.301708622,0.34471841,DB0047610008469_,1.065027399,0.327162125,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,36178,DB00476,10044565,728,16529,248,5929,0.504365521,1.052955635,0.907510439,1.224935053,0.665390872,DB0047610044565_,0.407380634,0.051601101,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,36180,DB00476,10060800,126,17131,16,6161,1.35856504646019e-05,2.832261592,1.675981123,5.111424803,0.000142101,DB0047610060800_,8.858975259,1.041075542,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,duloxetine,DB00476
,36190,DB00264,10009033,191,29416,161,24731,1,0.997391213,0.803889766,1.238724418,1,DB0026410009033_,0,-0.002612196,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,36191,DB00588,10038695,143,16381,80,8388,0.523241257,0.915306694,0.690436933,1.22058763,0.681574891,DB0058810038695_,0.383349143,-0.088496086,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,36192,DB01409,10038695,75,5956,87,3879,0.000338233,0.561496958,0.405601519,0.775753704,0.002229021,DB0140910038695_,6.106192741,-0.577148922,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,36202,DB00374,10018964,168,17548,75,5649,0.024028996,0.721105221,0.545161683,0.961452256,0.071294974,DB0037410018964_,2.640929451,-0.326970215,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,36203,DB00820,10018964,99,11816,54,5762,0.54499872,0.894023988,0.634368849,1.271710234,0.699866541,DB0082010018964_,0.356865617,-0.112022672,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,36204,DB06403,10018964,124,21347,50,6611,0.127870647,0.768044568,0.548178241,1.090406799,0.252627304,DB0640310018964_,1.375839982,-0.263907517,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,36205,DB00374,10022061,101,17615,26,5698,0.351168626,1.256553649,0.808935615,2.017507014,0.520874064,DB0037410022061_,0.652246986,0.228372774,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,36206,DB00820,10022061,43,11872,14,5802,0.205340202,1.501014969,0.804704495,2.973216758,0.355569499,DB0082010022061_,1.034034551,0.406141525,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,36208,DB00374,10022093,56,17660,9,5715,0.058676329,2.013430095,0.987649707,4.633673606,0.141023848,DB0037410022093_,1.958826265,0.699839783,NA,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,36214,DB00374,10047924,120,17596,20,5704,0.004081288,1.944836203,1.203712059,3.300877654,0.017365707,DB0037410047924_,4.053257876,0.665177759,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,36215,DB00820,10047924,84,11831,20,5796,0.003137118,2.057504583,1.250348587,3.542138878,0.014029629,DB0082010047924_,4.266583835,0.721493881,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,36216,DB06403,10047924,106,21365,19,6642,0.026321673,1.734307797,1.056776568,2.996545469,0.076466088,DB0640310047924_,2.570907929,0.55060837,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,36217,DB00374,10048634,401,17315,95,5629,0.005102656,1.372197896,1.092328661,1.738430117,0.020794313,DB0037410048634_,3.873075767,0.316413758,NA,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,36218,DB00820,10048634,134,11781,25,5791,1.49726873287814e-06,2.634609108,1.707396778,4.221338345,2.05566511588937e-05,DB0082010048634_,10.79232601,0.968734825,NA,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,36219,DB06403,10048634,120,21351,20,6641,0.007060619,1.866124023,1.155166407,3.16718911,0.026969175,DB0640310048634_,3.613060735,0.623863565,NA,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,36220,DB00374,10053425,52,17664,10,5714,0.140439472,1.682017997,0.844935627,3.714664583,0.270455822,DB0037410053425_,1.307646514,0.519994261,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,36223,DB00820,10053483,242,11673,63,5753,2.61037151032132e-06,1.893096446,1.42658496,2.544065135,3.34618947324047e-05,DB0082010053483_,10.30510324,0.63821382,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,36224,DB00374,10053664,100,17616,11,5713,0.000142955,2.948265108,1.577391923,6.100062233,0.001082357,DB0037410053664_,6.828614101,1.081216898,female,10053664,Infusion site pruritus,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,36231,DB05259,10002198,50,11220,12,2716,1,1.008615511,0.528727174,2.08385457,1,DB0525910002198_,0,0.008578609,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,glatiramer,DB05259
,36232,DB00203,10003119,59,13819,35,8903,0.751362882,1.086044568,0.702435358,1.701751685,0.859592756,DB0020310003119_,0.151296542,0.082542259,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,sildenafil,DB00203
,36233,DB00559,10003119,36,9623,14,3292,0.744974323,0.879701883,0.462314191,1.767936617,0.854422291,DB0055910003119_,0.157329721,-0.128172198,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,bosentan,DB00559
,36237,DB00060,10010305,129,9379,33,2432,1,1.013638421,0.684984906,1.538461176,1,DB0006010010305_,0,0.013546255,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,interferon beta-1a,DB00060
,36238,DB00108,10010305,130,10064,32,3263,0.197277864,1.317124386,0.886873653,2.008935371,0.345696577,DB0010810010305_,1.062193834,0.275450865,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,natalizumab,DB00108
,36242,DB00060,10016322,171,9337,48,2417,0.613211947,0.922192622,0.663732609,1.302401586,0.754972061,DB0006010016322_,0.281074535,-0.081001159,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,36243,DB00108,10016322,94,10100,23,3272,0.279335531,1.323971878,0.830468937,2.193359917,0.443150221,DB0010810016322_,0.813846467,0.280636217,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,36248,DB00108,10024855,69,10125,21,3274,0.902221887,1.062443015,0.642763553,1.82651515,0.957195726,DB0010810024855_,0.043747388,0.060570988,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,36249,DB00060,10033557,49,9459,7,2458,0.183077098,1.818900032,0.818210124,4.766586078,0.327738305,DB0006010033557_,1.11553984,0.59823194,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,interferon beta-1a,DB00060
,36253,DB00060,10042209,146,9362,19,2446,0.002575535,2.007499447,1.237346677,3.437572479,0.011942829,DB0006010042209_,4.427624275,0.696889891,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,interferon beta-1a,DB00060
,36254,DB00333,10016173,61,3010,30,3122,0.000678708,2.108734852,1.336581929,3.392261562,0.00399194,DB0033310016173_,5.523478039,0.746088171,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,methadone,DB00333
,36256,DB08908,10019196,45,10628,13,3266,1,1.063711937,0.563085925,2.152198323,1,DB0890810019196_,0,0.061764618,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,dimethyl fumarate,DB08908
,36260,DB08908,10060795,43,10630,12,3267,0.874035299,1.101285496,0.569687809,2.297047433,0.945309283,DB0890810060795_,0.056243122,0.09647813,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,dimethyl fumarate,DB08908
,36262,DB00005,10074586,37,128045,13,42406,0.870220914,0.942585673,0.489627205,1.932697814,0.94233451,DB0000510074586_,0.059394961,-0.059128464,NA,10074586,Injection site hypoaesthesia,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,36263,DB00115,10002855,329,18096,102,10370,2.30799428225174e-08,1.848345068,1.473799305,2.334519585,4.7711859778991e-07,DB0011510002855_,14.55550074,0.614290681,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,36264,DB00193,10002855,355,18965,98,8604,7.86086541488776e-06,1.643398298,1.308486487,2.080102891,8.80182523664856e-05,DB0019310002855_,9.337966352,0.496766231,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,36265,DB00557,10002855,168,5819,56,3011,0.004184434,1.552258455,1.136792606,2.146925171,0.01771854,DB0055710002855_,4.033143706,0.439710938,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,hydroxyzine,DB00557
,36266,DB00761,10002855,211,15096,64,8561,6.40510328654779e-06,1.869624616,1.405279224,2.516517486,7.34496602702176e-05,DB0076110002855_,9.518910281,0.625737671,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,potassium chloride,DB00761
,36269,DB06724,10002855,145,7784,36,3883,8.87506615844937e-05,2.009127902,1.383412482,2.986569285,0.000720559,DB0672410002855_,7.235482668,0.697700748,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,calcium carbonate,DB06724
,36280,DB00115,10007882,139,18286,83,10389,0.726351755,0.951469589,0.718991208,1.265700494,0.839835939,DB0011510007882_,0.174548717,-0.049747554,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,36281,DB00193,10007882,126,19194,68,8634,0.242782672,0.833527732,0.615073474,1.137822786,0.401038046,DB0019310007882_,0.913698978,-0.182088306,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,tramadol,DB00193
,36283,DB00999,10007882,132,21298,78,12161,0.829205806,0.966268572,0.724249205,1.29656569,0.910277089,DB0099910007882_,0.094006232,-0.034313459,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,36285,DB06724,10007882,77,7852,37,3882,0.920691224,1.028906606,0.685140328,1.569885329,0.964850044,DB0672410007882_,0.035782584,0.028496691,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,36286,DB00193,10012378,366,18954,109,8593,9.20900544126361e-05,1.522272888,1.223949509,1.906125218,0.000743652,DB0019310012378_,7.203937449,0.420204539,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,36287,DB00557,10012378,141,5846,53,3014,0.05508713,1.371555217,0.990150438,1.924327248,0.134500508,DB0055710012378_,2.006187305,0.315945291,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,hydroxyzine,DB00557
,36289,DB00996,10012378,795,38158,274,22151,2.37869393256745e-14,1.684304197,1.464891473,1.941278621,1.32888352853423e-12,DB0099610012378_,27.34668198,0.521352539,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,36291,DB06724,10012378,140,7789,28,3891,1.97147175825192e-06,2.4975921,1.652066446,3.90089718,2.61387819246667e-05,DB0672410012378_,10.55209045,0.915327108,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,calcium carbonate,DB06724
,36292,DB00557,10022437,146,5841,66,3001,0.419743054,1.136522294,0.841150935,1.549307952,0.588667275,DB0055710022437_,0.529894153,0.12797298,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,hydroxyzine,DB00557
,36293,DB00761,10022437,233,15074,105,8520,0.05960244,1.254251333,0.990342888,1.597141888,0.142721156,DB0076110022437_,1.94686251,0.226538847,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,potassium chloride,DB00761
,36296,DB06724,10022437,146,7783,51,3868,0.032333461,1.422688978,1.025123948,2.002181655,0.089816117,DB0672410022437_,2.409990839,0.352548727,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,calcium carbonate,DB06724
,36297,DB00193,10023230,52,19268,8,8694,0.001976825,2.932755396,1.382748028,7.152484153,0.009634867,DB0019310023230_,4.642366772,1.075942389,female,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,36298,DB00331,10023230,46,24900,27,20725,0.159130249,1.418029213,0.862816909,2.373061461,0.296319473,DB0033110023230_,1.216317104,0.349268029,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,36302,DB00999,10023230,44,21386,15,12224,0.103112756,1.676636105,0.914810129,3.244965705,0.215678097,DB0099910023230_,1.533968276,0.516789468,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,36305,DB00193,10033371,1037,18283,277,8425,1.58182250315084e-16,1.725097723,1.505560618,1.981878039,1.1597825521707e-14,DB0019310033371_,32.08795877,0.5452837,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,36306,DB00557,10033371,258,5729,63,3004,1.27719232008365e-08,2.147177302,1.618296351,2.885484711,2.8010847003253e-07,DB0055710033371_,15.08808892,0.764154097,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,36309,DB06724,10033371,304,7625,72,3847,1.34120002617891e-09,2.130095597,1.637380237,2.802236677,3.63250311057316e-08,DB0672410033371_,17.13075877,0.75616686,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,36310,DB00115,10048334,96,18329,15,10457,1.45265056783645e-07,3.651173696,2.105639976,6.780712113,2.54932182066522e-06,DB0011510048334_,12.87968319,1.295048676,female,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,36311,DB00193,10048334,101,19219,26,8676,0.009266764,1.753593853,1.12929899,2.814672,0.033490567,DB0019310048334_,3.396491475,0.561667313,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,36313,DB00761,10048334,48,15259,13,8612,0.016017553,2.083836293,1.110517594,4.195009465,0.051869086,DB0076110048334_,2.959032307,0.734210566,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,36315,DB00996,10048334,176,38777,65,22360,0.001986993,1.561326684,1.167820788,2.109613748,0.009674558,DB0099610048334_,4.63825573,0.445535898,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,36316,DB00999,10048334,74,21356,27,12212,0.048706992,1.567217514,0.995775739,2.535228581,0.122618838,DB0099910048334_,2.098674612,0.449301763,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,36331,DB00497,10022116,49,19218,22,16353,0.0120474,1.895171955,1.123916754,3.292995127,0.041267467,DB0049710022116_,3.187680802,0.639309576,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,36336,DB00497,10048334,54,19213,49,16326,0.766976467,0.936467948,0.623869886,1.408656473,0.871895875,DB0049710048334_,0.137085271,-0.065639983,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,36340,DB00497,10049119,38,19229,22,16353,0.156047893,1.468912904,0.846527892,2.608600928,0.292228475,DB0049710049119_,1.230219336,0.384522606,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,36345,DB00335,10051055,44,8422,51,5414,0.004339053,0.554650459,0.361404423,0.848108147,0.018243943,DB0033510051055_,4.003922149,-0.589417168,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,atenolol,DB00335
,36352,DB00203,10024855,209,13669,104,8834,0.03095083,1.298757921,1.020076633,1.662012014,0.086819546,DB0020310024855_,2.443923499,0.261408362,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,36353,DB00682,10024855,225,19234,141,16223,0.006042705,1.34592444,1.084428963,1.675130571,0.023796915,DB0068210024855_,3.738199309,0.297081093,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,36354,DB14500,10024855,62,7747,36,4037,0.594957413,0.897470229,0.58472647,1.395939476,0.740632518,DB1450010024855_,0.300250704,-0.10817533,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,potassium,DB14500
,36358,DB00005,10040872,117,127965,45,42374,0.413049462,0.860981157,0.605490288,1.243115887,0.58247298,DB0000510040872_,0.540472481,-0.14968266,NA,10040872,Skin infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,36361,DB00230,10008531,186,19488,37,8614,2.43615569535057e-06,2.221971672,1.553057121,3.256924458,3.14587828308965e-05,DB0023010008531_,10.36683235,0.798394942,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,36362,DB08895,10013700,1162,26952,193,6453,1.87649195579362e-06,1.441488894,1.233616145,1.691649085,2.50310028206218e-05,DB0889510013700_,10.59539539,0.365676534,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,tofacitinib,DB08895
,36363,DB01225,10013709,96,4948,86,4554,0.881110785,1.027393582,0.757708162,1.394887743,0.950230194,DB0122510013709_,0.051051015,0.027025092,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,36370,DB00722,10009887,76,25327,70,25962,0.561990449,1.112932584,0.793301018,1.563304823,0.714309427,DB0072210009887_,0.336439039,0.106998499,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,36371,DB00927,10009887,37,7460,19,4997,0.412704093,1.304396141,0.730148562,2.404163958,0.582107684,DB0092710009887_,0.541099824,0.265740206,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,36372,DB01076,10009887,70,25677,64,25519,0.665754706,1.086993067,0.762978683,1.55091014,0.796678137,DB0107610009887_,0.227304525,0.08341523,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,36374,DB06186,10009887,168,2041,295,3351,0.516428234,0.935016357,0.76278167,1.143310644,0.676073958,DB0618610009887_,0.391452804,-0.067191256,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,ipilimumab,DB06186
,36375,DB00005,10024670,132,127950,81,42338,2.26611141798988e-05,0.539257277,0.405774245,0.720329442,0.000222381,DB0000510024670_,8.411118636,-0.617562499,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,etanercept,DB00005
,36380,DB01224,10013709,432,7676,314,5603,0.969625148,1.004244945,0.862778034,1.169953173,1,DB0122410013709_,0,0.004235961,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,36381,DB08815,10013709,64,1390,45,658,0.058501669,0.673369441,0.447264785,1.020996765,0.140686044,DB0881510013709_,1.961224507,-0.395461154,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lurasidone,DB08815
,36382,DB14509,10013709,50,835,31,520,1,1.004439679,0.619989854,1.649588596,1,DB1450910013709_,0,0.004429853,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lithium carbonate,DB14509
,36384,DB01068,10042464,130,13633,50,6790,0.13102792,1.294974575,0.926456724,1.83472052,0.257260047,DB0106810042464_,1.357667849,0.258491062,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,36385,DB01224,10042464,97,8011,54,5863,0.115664923,1.314626997,0.931282042,1.872637631,0.234669393,DB0122410042464_,1.449577593,0.273552973,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,36404,DB00169,10028245,182,38509,64,18111,0.046863735,1.337471121,1.000122085,1.808216598,0.119200047,DB0016910028245_,2.126952133,0.290780608,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,36405,DB00186,10028245,47,16854,6,10002,4.31113667868687e-05,4.648352766,1.982494695,13.31085925,0.00038941,DB0018610028245_,7.850878512,1.536512913,female,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,36406,DB00193,10028245,42,19278,14,8688,0.386734396,1.352046874,0.723366547,2.68194555,0.556827035,DB0019310028245_,0.585500617,0.301619647,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,36408,DB00321,10028245,37,7410,13,2837,0.875027546,1.089671416,0.565117257,2.237520464,0.946097326,DB0032110028245_,0.055409833,0.085876198,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,36409,DB00425,10028245,54,12641,13,7471,0.002203724,2.454879538,1.321073873,4.906979518,0.010525101,DB0042510028245_,4.553992305,0.898077692,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,36410,DB00497,10028245,36,19231,16,16359,0.035771817,1.913916674,1.034943229,3.695431242,0.09703929,DB0049710028245_,2.332639334,0.649151757,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,36411,DB00635,10028245,51,33002,18,23776,0.009810907,2.041212587,1.172144078,3.713496356,0.035035621,DB0063510028245_,3.35138999,0.713544036,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,36415,DB00959,10028245,47,8031,11,4991,0.002559463,2.655170105,1.355711888,5.682184939,0.011879832,DB0095910028245_,4.432913139,0.976508722,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,36416,DB01068,10028245,81,13682,22,6818,0.011420442,1.834671272,1.132529477,3.090187527,0.039591971,DB0106810028245_,3.229128943,0.606865322,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,36435,DB00482,10003285,96,8163,33,3038,0.765347535,1.082659718,0.720357333,1.664311057,0.870533557,DB0048210003285_,0.138648972,0.079420716,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,36436,DB00482,10003983,41,8218,13,3058,0.758973441,1.17355655,0.615465068,2.390419716,0.865568244,DB0048210003983_,0.144369058,0.160038924,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,36442,DB01115,10005750,53,3547,26,2242,0.352103853,1.288412732,0.788849818,2.153156545,0.521853004,DB0111510005750_,0.650369332,0.25341102,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,nifedipine,DB01115
,36454,DB08816,10012735,27,1124,43,1859,0.901033044,1.03852364,0.613359899,1.730314618,0.956856375,DB0881610012735_,0.044101977,0.037800127,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ticagrelor,DB08816
,36457,DB00584,10013968,100,1981,76,1798,0.279714851,1.194185523,0.871012467,1.642699947,0.443542599,DB0058410013968_,0.812961431,0.177464382,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enalapril,DB00584
,36458,DB08816,10013968,150,1001,259,1643,0.661309802,0.950602245,0.760440081,1.185349518,0.793396693,DB0881610013968_,0.231431939,-0.050659553,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ticagrelor,DB08816
,36467,DB00727,10013700,227,3616,111,4062,3.98350901721151e-13,2.297061998,1.814082532,2.922474456,1.8832110524713e-11,DB0072710013700_,24.6954577,0.831630914,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,nitroglycerin,DB00727
,36481,DB09053,10016173,93,2192,121,3931,0.024627131,1.378232539,1.034900368,1.83075045,0.072684048,DB0905310016173_,2.621633347,0.32080191,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ibrutinib,DB09053
,36484,DB00316,10018916,45,65429,26,36927,0.902371157,0.976802904,0.589703745,1.649548895,0.957195726,DB0031610018916_,0.043747388,-0.023470384,NA,10018916,Haemolytic anaemia,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,36492,DB00193,10028391,110,19210,57,8645,0.401857236,0.868485443,0.624452365,1.219118425,0.571627429,DB0019310028391_,0.559267847,-0.141004455,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,36493,DB00316,10028391,373,65101,167,36786,0.013398939,1.262109288,1.048299282,1.524712967,0.044949366,DB0031610028391_,3.102218629,0.232784359,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,36495,DB09053,10030124,33,2252,55,3997,0.823239656,1.064908667,0.667727116,1.674873094,0.906206603,DB0905310030124_,0.098487961,0.062889037,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,ibrutinib,DB09053
,36496,DB00193,10035598,100,19220,56,8646,0.193651214,0.803324234,0.572879289,1.136147863,0.341252491,DB0019310035598_,1.075132633,-0.218996868,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,36497,DB09053,10035598,57,2228,108,3944,0.742610625,0.934274668,0.662695253,1.305435933,0.852566948,DB0905310035598_,0.159503541,-0.067984807,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibrutinib,DB09053
,36509,DB00983,10068319,46,3455,8,1732,0.00331548,2.882022391,1.343064763,7.08591428,0.014667575,DB0098310068319_,4.22211601,1.058492267,female,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,formoterol,DB00983
,36517,DB00635,10018867,54,32999,107,23687,3.45690813349247e-10,0.362264593,0.25606513,0.50732626,1.04083425302233e-08,DB0063510018867_,18.38065819,-1.015380414,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,36524,DB00635,10020524,17,33036,35,23759,0.000333623,0.349324221,0.183454114,0.64066318,0.002203063,DB0063510020524_,6.117906811,-1.051754789,male,10020524,Hydronephrosis,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,36538,DB00555,10012174,50,6997,26,3460,0.808155689,0.950962094,0.579640753,1.594431992,0.896477889,DB0055510012174_,0.10928165,-0.050281076,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,lamotrigine,DB00555
,36542,DB06413,10028813,121,1435,31,643,0.005928658,1.748577308,1.155837198,2.7154725,0.023443881,DB0641310028813_,3.753145755,0.55880249,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,armodafinil,DB06413
,36547,DB00641,10028411,250,13874,197,12278,0.232414331,1.12303555,0.926506143,1.362808135,0.388848903,DB0064110028411_,0.944564434,0.116035332,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,36548,DB00641,10033425,396,13728,203,12272,8.32133646973178e-11,1.743799877,1.465993004,2.079279529,2.73921514222793e-09,DB0064110033425_,19.7155944,0.556066569,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,36563,DB00331,10005635,22,24924,35,20717,0.016521893,0.522486957,0.291862913,0.916272972,0.053133748,DB0033110005635_,2.934943002,-0.649155259,NA,10005635,Blood lactic acid increased,10022891,Investigations,Inv,metformin,DB00331
,36568,DB00215,10010305,117,10986,83,5193,0.005990309,0.666332097,0.497654251,0.895566499,0.023634482,DB0021510010305_,3.745048543,-0.405967089,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,36569,DB00956,10010305,67,5747,42,3425,0.842236858,0.950716805,0.635345374,1.436936303,0.919665828,DB0095610010305_,0.083744906,-0.050539047,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,hydrocodone,DB00956
,36570,DB01156,10011224,173,13449,65,6263,0.160912956,1.239398009,0.925206211,1.677607669,0.298732002,DB0115610011224_,1.208208421,0.214625785,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,36574,DB01075,10013395,46,19902,24,11073,0.900772557,1.06639099,0.63715244,1.827541061,0.956764412,DB0107510013395_,0.044198092,0.064280041,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,36576,DB01156,10013395,40,13582,22,6306,0.584670652,0.844186358,0.489344667,1.492683242,0.732371522,DB0115610013395_,0.31146735,-0.169382006,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,36579,DB00331,10013916,40,24906,26,20726,0.386733005,1.280251672,0.762003233,2.185809196,0.556827035,DB0033110013916_,0.585500617,0.247056677,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,metformin,DB00331
,36582,DB01104,10013916,49,15414,21,7265,0.798029144,1.099750571,0.646771613,1.932212233,0.890838937,DB0110410013916_,0.115591635,0.0950834,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,36583,DB01156,10013916,51,13571,21,6307,0.704646121,1.128644801,0.666255172,1.977234634,0.822904333,DB0115610013916_,0.194915327,0.121017622,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,36584,DB01156,10013968,367,13255,115,6213,0.000132943,1.495828137,1.207175173,1.864963834,0.001016406,DB0115610013968_,6.891482617,0.402679991,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,36591,DB00215,10027175,166,10937,36,5240,4.64466375630945e-06,2.209127093,1.530498287,3.267295358,5.54728251904863e-05,DB0021510027175_,9.799617293,0.792597457,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,36592,DB00956,10027175,85,5729,29,3438,0.008308998,1.758827613,1.139045112,2.787609022,0.030693838,DB0095610027175_,3.483693354,0.564647458,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,36593,DB01104,10027175,177,15286,65,7221,0.083802514,1.286303361,0.961435057,1.739153004,0.184755636,DB0110410027175_,1.688721211,0.251772493,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,36594,DB01156,10027175,180,13442,65,6263,0.08418152,1.290200149,0.964845323,1.743690973,0.185384062,DB0115610027175_,1.685325596,0.254797361,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,36596,DB00295,10027417,23,14640,42,9560,5.92351945535807e-05,0.357612842,0.20516596,0.60887375,0.000510407,DB0029510027417_,7.580301767,-1.028304323,male,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,morphine,DB00295
,36598,DB01075,10027417,63,19885,49,11048,0.092600428,0.714370678,0.483610901,1.06058244,0.199393975,DB0107510027417_,1.612472637,-0.336353294,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,diphenhydramine,DB01075
,36600,DB01156,10027417,56,13566,30,6298,0.561718273,0.866613502,0.546069822,1.400308674,0.714032538,DB0115610027417_,0.336826746,-0.14316219,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,bupropion,DB01156
,36613,DB01104,10028622,41,15422,15,7271,0.474194356,1.288625646,0.697819821,2.5079331,0.6398952,DB0110410028622_,0.446450867,0.253576259,NA,10028622,Myoclonus,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,36614,DB01156,10028622,46,13576,23,6305,0.795901753,0.928850236,0.550981941,1.607008676,0.889464732,DB0115610028622_,0.117135422,-0.073807763,NA,10028622,Myoclonus,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,36622,DB00295,10040108,17,14646,54,9548,4.77812713116196e-10,0.205246984,0.111489028,0.359804637,1.40641737561693e-08,DB0029510040108_,18.07963514,-1.583541224,male,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,morphine,DB00295
,36625,DB01104,10040108,107,15356,106,7180,7.7111506149996e-08,0.471987185,0.356864224,0.624331584,1.43140956154848e-06,DB0110410040108_,13.45685089,-0.750803444,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,36626,DB00215,10043071,71,11032,47,5229,0.092228886,0.716015891,0.487611219,1.059942478,0.198789362,DB0021510043071_,1.615509495,-0.334052918,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,citalopram,DB00215
,36627,DB00331,10043071,132,24814,89,20663,0.13618707,1.235031889,0.936170611,1.635741409,0.264358402,DB0033110043071_,1.330449512,0.21109679,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,metformin,DB00331
,36629,DB01104,10043071,66,15397,34,7252,0.668475987,0.9143022,0.595112358,1.427922986,0.798551101,DB0110410043071_,0.224956317,-0.089594128,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,sertraline,DB01104
,36630,DB01156,10043071,138,13484,64,6264,1,1.001687194,0.738302976,1.371399771,1,DB0115610043071_,0,0.001685772,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,bupropion,DB01156
,36631,DB00215,10044565,132,10971,58,5218,0.640325028,1.082433014,0.78759536,1.503394605,0.777321019,DB0021510044565_,0.251901862,0.079211298,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,36632,DB00295,10044565,102,14561,93,9509,0.02248868,0.716269533,0.534793484,0.960303963,0.06769913,DB0029510044565_,2.69268195,-0.33369874,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,morphine,DB00295
,36633,DB00956,10044565,78,5736,30,3437,0.044899535,1.557844445,1.008086115,2.464789206,0.115376568,DB0095610044565_,2.159553997,0.4433031,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,36634,DB01075,10044565,187,19761,128,10969,0.076126122,0.810960186,0.643376335,1.024831527,0.171705935,DB0107510044565_,1.761971944,-0.209536318,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,36635,DB01156,10044565,255,13367,100,6228,0.150692557,1.188079161,0.937238509,1.51569468,0.284888976,DB0115610044565_,1.255655734,0.172337852,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,36637,DB00295,10046555,29,14634,52,9550,1.02454082831123e-05,0.363958838,0.222615354,0.584514151,0.000110915,DB0029510046555_,9.106750364,-1.0107145,male,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,morphine,DB00295
,36638,DB00331,10046555,27,24919,45,20707,0.004226545,0.498596962,0.297375488,0.821445378,0.01786089,DB0033110046555_,4.025141874,-0.6959572,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,36640,DB01104,10046555,27,15436,32,7254,0.000418201,0.396528035,0.228362807,0.683789995,0.002658058,DB0110410046555_,5.930159359,-0.925008534,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,sertraline,DB01104
,36642,DB00215,10049848,84,11019,28,5248,0.105323672,1.428784499,0.920431335,2.279741523,0.219073571,DB0021510049848_,1.518347667,0.356824082,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,36643,DB00295,10049848,64,14599,40,9562,0.841462675,1.047965145,0.694507728,1.598298295,0.919125932,DB0029510049848_,0.084332135,0.046850327,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,morphine,DB00295
,36644,DB00956,10049848,41,5773,23,3444,0.897104116,1.063450626,0.622081989,1.85994536,0.956338178,DB0095610049848_,0.044643686,0.061518928,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,36645,DB01075,10049848,88,19860,51,11046,0.859265812,0.959727783,0.671604812,1.384062404,0.933334743,DB0107510049848_,0.068991361,-0.041105594,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,36646,DB01104,10049848,134,15329,72,7214,0.368658664,0.875872469,0.651959696,1.18483733,0.53831499,DB0110410049848_,0.619311407,-0.132534782,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,36647,DB01156,10049848,103,13519,51,6277,0.728260303,0.937727335,0.663145604,1.340591528,0.841494728,DB0115610049848_,0.17257553,-0.06429606,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,36648,DB00295,10070863,671,13992,558,9044,2.09388828137587e-05,0.777284307,0.691465165,0.873963414,0.000207729,DB0029510070863_,8.479275214,-0.251949092,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,36649,DB00331,10070863,514,24432,610,20142,1.7606985629106e-09,0.694680498,0.61559041,0.783646278,4.65359092268529e-08,DB0033110070863_,16.88304158,-0.364303254,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,36650,DB00956,10070863,490,5324,315,3152,0.285821207,0.920954383,0.792213818,1.071744175,0.450489323,DB0095610070863_,0.797420903,-0.082344773,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocodone,DB00956
,36651,DB06643,10005956,165,52256,16,7499,0.144224972,1.479886537,0.883967029,2.651447293,0.275876243,DB0664310005956_,1.28780291,0.39196542,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,36652,DB06643,10051085,89,52332,9,7506,0.362714263,1.418359386,0.71406929,3.204570125,0.532250908,DB0664310051085_,0.630640268,0.349500842,NA,10051085,Endodontic procedure,10042613,Surgical and medical procedures,Surg,denosumab,DB06643
,36654,DB01041,10070863,83,2962,97,3021,0.405391766,0.872734034,0.640096117,1.187669504,0.575055776,DB0104110070863_,0.553288241,-0.136124427,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,thalidomide,DB01041
,36656,DB01101,10013709,194,7395,76,3832,0.043691656,1.322727216,1.006411398,1.753211371,0.112961079,DB0110110013709_,2.180711957,0.279695678,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,36660,DB08895,10025482,1191,26923,192,6454,1.88843573634166e-07,1.486985488,1.272455446,1.745259856,3.22635900745794e-06,DB0889510025482_,12.6441563,0.396750908,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,36662,DB00584,10011906,67,2014,75,1799,0.19955715,0.798016178,0.56164073,1.131865505,0.348505726,DB0058410011906_,1.054100619,-0.225626408,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,enalapril,DB00584
,36665,DB00153,10003239,301,7122,67,3372,4.58363568725985e-09,2.126920143,1.621719086,2.823855025,1.11093466149954e-07,DB0015310003239_,16.01289395,0.754674991,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,36666,DB00165,10003239,66,2079,20,1346,0.002362641,2.136085624,1.271809654,3.73797502,0.011143425,DB0016510003239_,4.496905653,0.758975007,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pyridoxine,DB00165
,36667,DB00281,10003239,208,11250,75,5596,0.01829404,1.379498429,1.052347143,1.824741158,0.057577543,DB0028110003239_,2.854622661,0.321719976,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lidocaine,DB00281
,36669,DB01190,10003239,86,4848,25,2260,0.039463208,1.603534858,1.013830408,2.621025648,0.104570838,DB0119010003239_,2.257890564,0.472210479,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,clindamycin,DB01190
,36670,DB00165,10003988,45,2100,23,1343,0.45149621,1.251148622,0.7372404,2.177139948,0.619167208,DB0016510003988_,0.479379917,0.224062027,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pyridoxine,DB00165
,36672,DB01190,10003988,61,4873,26,2259,0.816766429,1.087603447,0.674771135,1.798716767,0.901913819,DB0119010003988_,0.103236308,0.083976603,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,clindamycin,DB01190
,36673,DB00153,10006451,123,7300,19,3420,6.38730435756885e-07,3.032633799,1.857878839,5.217533724,9.61295705918679e-06,DB0015310006451_,11.55239868,1.109431483,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,ergocalciferol,DB00153
,36675,DB00215,10006451,118,10985,21,5255,6.07266405601217e-06,2.687903875,1.677742835,4.508795849,7.0070225949201e-05,DB0021510006451_,9.566012591,0.988761661,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,citalopram,DB00215
,36676,DB00281,10006451,253,11205,53,5618,5.83020487466885e-10,2.393291857,1.770547198,3.287948307,1.68867146149499e-08,DB0028110006451_,17.89673864,0.872669764,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,lidocaine,DB00281
,36685,DB00563,10007697,57,46589,11,15337,0.121235497,1.705763534,0.885109556,3.608652431,0.243211221,DB0056310007697_,1.413824989,0.534012831,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,36686,DB00996,10007697,58,38895,23,22402,0.134742857,1.452414536,0.881835514,2.46792076,0.262254734,DB0099610007697_,1.338438981,0.373227369,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,36688,DB00158,10007882,143,16672,89,8015,0.057590395,0.772471117,0.587899817,1.019526796,0.138909249,DB0015810007882_,1.973934442,-0.25816066,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,folic acid,DB00158
,36690,DB00215,10007882,39,11064,23,5253,0.415714816,0.805099248,0.46846243,1.413545326,0.584944939,DB0021510007882_,0.536237557,-0.216789719,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,citalopram,DB00215
,36691,DB00281,10007882,86,11372,43,5628,1,0.989796702,0.677670532,1.464638662,1,DB0028110007882_,0,-0.010255709,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,lidocaine,DB00281
,36693,DB00563,10007882,246,46400,101,15247,0.061471376,0.800346886,0.631883041,1.020034036,0.14616447,DB0056310007882_,1.923022787,-0.222710038,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,methotrexate,DB00563
,36694,DB01190,10007882,71,4863,39,2246,0.408840509,0.840847697,0.559185127,1.280889656,0.578212735,DB0119010007882_,0.547813425,-0.173344733,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,clindamycin,DB01190
,36695,DB00165,10012735,140,2005,68,1298,0.066572728,1.332737855,0.981688802,1.823506081,0.155179795,DB0016510012735_,1.863170866,0.287235364,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pyridoxine,DB00165
,36696,DB00461,10012735,39,1051,16,309,0.257015542,0.716821726,0.385191539,1.393746261,0.417892709,DB0046110012735_,0.872530557,-0.332928108,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,nabumetone,DB00461
,36697,DB01190,10012735,279,4655,119,2166,0.471185823,1.090922137,0.871530797,1.372129457,0.637438913,DB0119010012735_,0.45029683,0.087023336,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,clindamycin,DB01190
,36716,DB00563,10023215,66,46580,37,15311,0.011572824,0.586341951,0.386126228,0.902630943,0.040030488,DB0056310023215_,3.218113924,-0.533852125,NA,10023215,Joint effusion,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,36719,DB00153,10028391,70,7353,16,3423,0.009954002,2.036553856,1.168756218,3.762290081,0.035433497,DB0015310028391_,3.340097661,0.711259093,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,36721,DB00215,10028391,47,11056,11,5265,0.033955654,2.034647593,1.03904714,4.353871901,0.093311485,DB0021510028391_,2.371812079,0.710322631,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,36722,DB00281,10028391,49,11409,17,5654,0.238615147,1.428390332,0.807464558,2.648130282,0.396309524,DB0028110028391_,0.925559747,0.356548168,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lidocaine,DB00281
,36725,DB00005,10031282,210,127872,25,42394,5.71334222868225e-08,2.785002089,1.834646435,4.402734944,1.09020109242042e-06,DB0000510031282_,13.72914839,1.024248623,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,36727,DB00158,10031282,59,16756,9,8095,0.000390028,3.16694265,1.559124096,7.269275546,0.00251118,DB0015810031282_,5.987002689,1.152766659,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,36730,DB00264,10031282,61,29546,12,24880,1.94236527594497e-07,4.280381998,2.281203915,8.736388176,3.30560513293711e-06,DB0026410031282_,12.61989101,1.454042258,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,36733,DB00996,10031282,57,38896,13,22412,0.001688661,2.526391934,1.366002535,5.03212497,0.008461816,DB0099610031282_,4.772191529,0.926792172,NA,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,36735,DB00126,10039073,104,10067,12,5933,1.05488383360894e-10,5.106859097,2.799673837,10.21365504,3.42527752518975e-09,DB0012610039073_,19.49208334,1.630584557,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,36736,DB00153,10039073,90,7333,7,3432,8.50053825517772e-09,6.017116455,2.79918879,15.4077068,1.9429273742378e-07,DB0015310039073_,15.45389986,1.79460815,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,36737,DB00158,10039073,561,16254,131,7973,6.21321946873495e-16,2.100591543,1.730315778,2.565352533,4.2364325223268e-14,DB0015810039073_,30.79246977,0.742218992,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,36740,DB00264,10039073,144,29463,45,24847,6.73563730241164e-10,2.698511773,1.917813847,3.862285518,1.93071130309586e-08,DB0026410039073_,17.76279226,0.992700426,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,36741,DB00281,10039073,48,11410,6,5665,0.000385222,3.971376484,1.695863655,11.36375521,0.002485713,DB0028110039073_,5.997195637,1.379112756,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,lidocaine,DB00281
,36743,DB00996,10039073,270,38683,56,22369,1.73345224265456e-14,2.78800891,2.083034523,3.789686141,9.87297772441498e-13,DB0099610039073_,27.64380471,1.025327689,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,36745,DB00126,10042128,92,10079,19,5926,6.65522338871289e-06,2.8467747,1.721524802,4.947232676,7.60080585584698e-05,DB0012610042128_,9.48467119,1.046186669,female,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,36746,DB00153,10042128,46,7377,11,3428,0.045756537,1.943135438,0.989929032,4.165445032,0.117014008,DB0015310042128_,2.145461628,0.664302873,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,36747,DB00158,10042128,117,16698,37,8067,0.024685146,1.52765363,1.046335658,2.277447558,0.07281848,DB0015810042128_,2.619785515,0.423732983,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,36749,DB00215,10042128,54,11049,10,5266,0.004433983,2.573539056,1.29619466,5.672832703,0.01855257,DB0021510042128_,3.987146947,0.945282016,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,36750,DB00264,10042128,168,29439,93,24799,0.001163431,1.521714209,1.173542952,1.983327803,0.006244163,DB0026410042128_,5.076108251,0.419837468,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,36751,DB00281,10042128,68,11390,20,5651,0.04065262,1.686818817,1.010874637,2.935857702,0.106940964,DB0028110042128_,2.235478338,0.522844398,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,36753,DB00996,10042128,191,38762,72,22353,0.002010279,1.529774933,1.160099701,2.036156543,0.009768936,DB0099610042128_,4.628547766,0.425120622,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,36759,DB00264,10043224,32,29575,19,24873,0.261396434,1.416433552,0.778599208,2.645604004,0.422935906,DB0026410043224_,0.860534634,0.348142129,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,36762,DB00563,10043224,108,46538,18,15330,0.005132058,1.976319052,1.19269143,3.461438953,0.020884987,DB0056310043224_,3.868724689,0.68123605,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,36763,DB00996,10043224,46,38907,13,22412,0.021135649,2.038272612,1.082462035,4.113709878,0.064580127,DB0099610043224_,2.739848541,0.712102691,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,36765,DB00005,10047626,62,128020,18,42401,0.698937928,1.14081818,0.666055251,2.049511169,0.818989989,DB0000510047626_,0.199683418,0.131745707,NA,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,etanercept,DB00005
,36771,DB00264,10047626,41,29566,11,24881,0.000387787,3.136471546,1.582936699,6.768300521,0.002500426,DB0026410047626_,5.991293985,1.143098456,female,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,36774,DB00563,10047626,46,46600,9,15339,0.16238764,1.682313498,0.813384251,3.910358064,0.30056712,DB0056310047626_,1.20208419,0.520169928,NA,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,36775,DB00996,10047626,42,38911,9,22416,0.005168818,2.688343407,1.28959446,6.282425675,0.02100207,DB0099610047626_,3.863134275,0.98892517,NA,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,36789,DB00165,10047700,80,2065,36,1330,0.081623646,1.43112098,0.947937493,2.197663799,0.181060596,DB0016510047700_,1.708923518,0.358458039,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pyridoxine,DB00165
,36791,DB00126,10048959,291,9880,103,5842,5.09313642906946e-06,1.67050264,1.326530978,2.117340498,6.02489158587267e-05,DB0012610048959_,9.71702598,0.513124563,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,36792,DB00153,10048959,138,7285,52,3387,0.208883277,1.233796742,0.88825707,1.736430105,0.359949974,DB0015310048959_,1.021790218,0.210096197,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,36793,DB00165,10048959,57,2088,21,1345,0.033866147,1.748165486,1.037897242,3.050991539,0.093114193,DB0016510048959_,2.373928657,0.558566945,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,pyridoxine,DB00165
,36794,DB00215,10048959,157,10946,53,5223,0.030969205,1.413457026,1.027151544,1.971692198,0.086866454,DB0021510048959_,2.443383348,0.346038495,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,36795,DB00281,10048959,149,11309,54,5617,0.050942583,1.370469932,0.995732492,1.910652094,0.126771673,DB0028110048959_,2.065367662,0.315153697,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,36797,DB00996,10048959,735,38218,356,22069,0.00698991,1.192243864,1.047864545,1.358327988,0.026759364,DB0099610048959_,3.620870828,0.175837132,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,36798,DB01190,10048959,58,4876,24,2261,0.720643081,1.120585866,0.683376331,1.890964013,0.835244985,DB0119010048959_,0.180030202,0.113851643,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,clindamycin,DB01190
,36806,DB00563,10049088,75,46571,17,15331,0.184043024,1.452299168,0.849168465,2.624431852,0.328996932,DB0056310049088_,1.111706853,0.373147934,NA,10049088,Osteopenia,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,36807,DB00996,10049088,47,38906,9,22416,0.001198861,3.008770352,1.457381509,6.984505555,0.006403589,DB0099610049088_,5.050896711,1.101531474,female,10049088,Osteopenia,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,36812,DB00264,10050296,43,29564,28,24864,0.340460137,1.29156323,0.783893168,2.159580369,0.509681895,DB0026410050296_,0.673968484,0.255853291,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,36815,DB00563,10050296,72,46574,14,15334,0.079269899,1.693153632,0.946396708,3.252099604,0.177185195,DB0056310050296_,1.730559793,0.526592845,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,36825,DB00563,10061598,40,46606,13,15335,1,1.012417152,0.530317173,2.063649925,1,DB0056310061598_,0,0.012340692,NA,10061598,Immunodeficiency,10021428,Immune system disorders,Immun,methotrexate,DB00563
,36828,DB00374,10054236,120,17596,26,5698,0.06618476,1.494512584,0.970572199,2.382840392,0.154492821,DB0037410054236_,1.86760765,0.401800123,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,36832,DB00451,10018838,119,47152,40,15379,0.853990826,0.97031876,0.672644629,1.426094924,0.928911602,DB0045110018838_,0.073741698,-0.030130643,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,36834,DB00588,10018838,40,16484,19,8449,0.890685751,1.07906358,0.610090705,1.97390624,0.954671384,DB0058810018838_,0.046388098,0.07609361,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,36835,DB00682,10018838,72,19387,110,16254,7.01034137763267e-05,0.54878515,0.401625183,0.745937967,0.000587586,DB0068210018838_,7.439488735,-0.600048263,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,warfarin,DB00682
,36838,DB00451,10018884,500,46771,197,15222,0.026912341,0.826017621,0.69836255,0.980130564,0.077820778,DB0045110018884_,2.55334681,-0.191139173,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,36840,DB01104,10018884,119,15344,53,7233,0.80568542,1.058399539,0.75858229,1.493841922,0.894884482,DB0110410018884_,0.111060639,0.056757898,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,sertraline,DB01104
,36854,DB06643,10011224,301,52120,41,7474,0.806366621,1.052769281,0.757112211,1.498336418,0.895314731,DB0664310011224_,0.110579968,0.051424103,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,denosumab,DB06643
,36855,DB00341,10020751,194,11211,66,5002,0.05814824,1.311398517,0.984918986,1.765028283,0.139942482,DB0034110020751_,1.966523781,0.271094138,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,cetirizine,DB00341
,36856,DB06643,10028411,1077,51344,86,7429,1.52277850906437e-08,1.81198068,1.451518837,2.2872503,3.27949472435534e-07,DB0664310028411_,14.93040629,0.594420545,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,36857,DB00341,10039101,117,11288,33,5035,0.020549653,1.581406078,1.06496367,2.406842448,0.06314562,DB0034110039101_,2.762311797,0.458314374,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,36858,DB06643,10039101,75,52346,16,7499,0.152688939,0.671531462,0.387530974,1.235318959,0.287721612,DB0664310039101_,1.245761892,-0.39819441,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,denosumab,DB06643
,36860,DB06643,10044044,156,52265,15,7500,0.164115544,1.49238495,0.876851363,2.732084863,0.302896878,DB0664310044044_,1.194362869,0.400375478,NA,10044044,Tooth loss,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,36864,DB06643,10048865,62,52359,9,7506,1,0.98756593,0.487770594,2.261469136,1,DB0664310048865_,0,-0.01251202,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,denosumab,DB06643
,36868,DB06643,10055798,45,52376,11,7504,0.108007202,0.586119842,0.298308329,1.257152692,0.223066654,DB0664310055798_,1.500284655,-0.534231002,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,denosumab,DB06643
,36873,DB00230,10010305,335,19339,128,8523,0.185912905,1.153422229,0.936572974,1.427604029,0.331348027,DB0023010010305_,1.104586016,0.142733375,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,36874,DB00230,10027590,31,19643,19,8632,0.281812303,0.716987303,0.392194912,1.344107993,0.445788307,DB0023010027590_,0.807911087,-0.332697147,NA,10027590,Middle insomnia,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,36875,DB00451,10027590,41,47230,14,15405,0.875917769,0.955208839,0.509936761,1.89771148,0.946806701,DB0045110027590_,0.054660324,-0.045825283,NA,10027590,Middle insomnia,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,36876,DB00230,10033425,1018,18656,405,8246,0.081499127,1.111000776,0.98621263,1.25334737,0.18087124,DB0023010033425_,1.70996988,0.105261209,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,36879,DB06228,10000087,149,15763,70,16006,4.39524820612087e-08,2.1613235,1.614950397,2.916540505,8.58952409649717e-07,DB0622810000087_,13.96755232,0.770720765,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,36881,DB00697,10005750,79,6017,15,1791,0.137059327,1.567545058,0.892552616,2.939754781,0.265590652,DB0069710005750_,1.325799057,0.449510738,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,tizanidine,DB00697
,36882,DB09068,10005750,41,2354,12,974,0.361075758,1.413612528,0.725007582,2.967823433,0.53098782,DB0906810005750_,0.633016197,0.346148505,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,vortioxetine,DB09068
,36888,DB08932,10005728,73,19370,20,6577,0.473570143,1.239323982,0.74661427,2.148266614,0.639496081,DB0893210005728_,0.447074787,0.214566055,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,macitentan,DB08932
,36889,DB08932,10038428,183,19260,62,6535,1,1.001494805,0.745927895,1.360260906,1,DB0893210038428_,0,0.001493689,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,macitentan,DB08932
,36892,DB08908,10046571,332,10341,94,3185,0.523239802,1.087813257,0.859534642,1.387652221,0.681574891,DB0890810046571_,0.383349143,0.084169495,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,dimethyl fumarate,DB08908
,36893,DB08908,10000059,235,10438,57,3222,0.10891184,1.272597341,0.946409364,1.735905714,0.224397235,DB0890810000059_,1.494337427,0.241059962,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,36894,DB00996,10017944,151,38802,69,22356,0.122681224,1.260885956,0.941818906,1.702466029,0.24526365,DB0099610017944_,1.405421524,0.231814614,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,36896,DB00635,10041232,53,33000,23,23771,0.047359923,1.659880149,0.999536033,2.838482909,0.120130816,DB0063510041232_,2.119174,0.506745401,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,36897,DB00635,10062244,107,32946,35,23759,2.50593350930681e-05,2.204611083,1.491924362,3.329823888,0.00024203,DB0063510062244_,8.326448906,0.790551114,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,36899,DB00321,10008190,40,7407,28,2822,0.019817094,0.544332073,0.326846517,0.91802006,0.061334815,DB0032110008190_,2.791407653,-0.608195791,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,36900,DB00321,10041466,39,7408,11,2839,0.430395332,1.358668487,0.681264669,2.945865809,0.598843525,DB0032110041466_,0.512754943,0.306505166,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,36901,DB00321,10044565,81,7366,44,2806,0.069631782,0.70130095,0.478672396,1.039463519,0.160648766,DB0032110044565_,1.828534877,-0.354818169,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,36904,DB00005,10061372,93,127989,16,42403,0.014222064,1.925581244,1.12541708,3.508185231,0.047167618,DB0000510061372_,3.054047689,0.655227867,NA,10061372,Streptococcal infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,36909,DB00668,10034829,40,10051,12,4291,0.362322115,1.423094247,0.731014593,2.982829824,0.532017026,DB0066810034829_,0.631079786,0.352833548,NA,10034829,Pharyngeal oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,36917,DB00668,10043521,42,10049,14,4289,0.467874669,1.280376599,0.684606363,2.541422621,0.634412468,DB0066810043521_,0.455055956,0.247154253,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,36919,DB01050,10043521,51,18057,21,9350,0.45525964,1.257469598,0.742533708,2.202244113,0.622784857,DB0105010043521_,0.473554154,0.229101446,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,36927,DB06403,10012174,192,21279,54,6607,0.547719711,1.103973882,0.811299219,1.524145008,0.702352064,DB0640310012174_,0.353320485,0.09891629,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ambrisentan,DB06403
,36928,DB06403,10024855,179,21292,69,6592,0.133189368,0.803169705,0.604286426,1.077860403,0.260191938,DB0640310024855_,1.346335697,-0.219189248,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,36929,DB00374,10053998,45,17671,15,5709,0.88118415,0.969214627,0.52978742,1.873304814,0.950252329,DB0037410053998_,0.05102772,-0.031269199,NA,10053998,Infusion site oedema,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,36936,DB00575,10013968,237,5007,131,3698,0.009620103,1.336141255,1.070130838,1.67412519,0.034511314,DB0057510013968_,3.366468065,0.289785799,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonidine,DB00575
,36944,DB00281,10021097,233,11225,222,5449,2.92478340997429e-12,0.509492283,0.42090395,0.616941015,1.22074587471201e-10,DB0028110021097_,22.82638889,-0.674340573,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,lidocaine,DB00281
,36946,DB00575,10021097,128,5116,147,3682,0.000148585,0.626727378,0.488659562,0.802953129,0.001116827,DB0057510021097_,6.797263391,-0.467243636,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,clonidine,DB00575
,36960,DB00281,10045555,73,11385,50,5621,0.083226475,0.7208209,0.495463863,1.056235123,0.183832596,DB0028110045555_,1.693729741,-0.327364577,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,36965,DB00281,10074903,45,11413,13,5658,0.093572604,1.716010254,0.908808081,3.470250529,0.201050877,DB0028110074903_,1.604197283,0.540001977,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,lidocaine,DB00281
,36967,DB00575,10074903,35,5209,20,3809,0.413623622,1.279625429,0.717250297,2.343272453,0.583001148,DB0057510074903_,0.539566123,0.246567402,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,clonidine,DB00575
,36971,DB00425,10005734,45,12650,30,7454,0.632508895,0.883882294,0.544189945,1.454451545,0.771216342,DB0042510005734_,0.259786345,-0.123431377,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,zolpidem,DB00425
,36975,DB00186,10002034,331,16570,168,9840,0.101966562,1.170043524,0.967130158,1.419686937,0.213893387,DB0018610002034_,1.542277582,0.157040948,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,lorazepam,DB00186
,36976,DB00715,10002034,63,4780,18,2269,0.056189,1.661294704,0.968500677,2.988760399,0.136426711,DB0071510002034_,1.991967725,0.50759724,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,paroxetine,DB00715
,36979,DB00186,10044565,218,16683,100,9908,0.035500105,1.294685522,1.015781176,1.659621117,0.096491417,DB0018610044565_,2.338301219,0.258267826,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,36981,DB00715,10044565,75,4768,41,2246,0.482719269,0.861717782,0.57916939,1.298055437,0.647024291,DB0071510044565_,0.435371441,-0.148827461,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,paroxetine,DB00715
,36985,DB00215,10015150,80,11023,19,5257,0.004839207,2.007975765,1.204517184,3.511799301,0.019944894,DB0021510015150_,3.914782093,0.697127133,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,citalopram,DB00215
,36986,DB00404,10015150,158,19734,46,9816,0.000997683,1.708486387,1.222066588,2.429578608,0.005490234,DB0040410015150_,5.204784368,0.535607825,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,36988,DB05259,10015150,152,11118,36,2692,1,1.022328503,0.70502472,1.51788685,1,DB0525910015150_,0,0.022082871,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,glatiramer,DB05259
,36989,DB00215,10022095,53,11050,18,5258,0.252322651,1.401070947,0.80660136,2.544277885,0.412456523,DB0021510022095_,0.885624479,0.337236906,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,36990,DB00404,10022095,90,19802,18,9844,0.000192769,2.485543249,1.485880682,4.385156502,0.001396617,DB0040410022095_,6.573702367,0.910491247,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,36991,DB00404,10027175,283,19609,78,9784,1.53808204930726e-06,1.810276637,1.402510397,2.359793332,2.10510214350645e-05,DB0040410027175_,10.76856147,0.593479672,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,36992,DB00425,10027175,172,12523,78,7406,0.055970241,1.304078202,0.990671459,1.729509226,0.136034309,DB0042510027175_,1.994848154,0.265496432,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,36993,DB00745,10027175,61,2516,34,1049,0.209752733,0.748073453,0.480686123,1.181392175,0.360881018,DB0074510027175_,1.019206964,-0.290254107,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,modafinil,DB00745
,36995,DB05259,10042674,86,11184,15,2713,0.259010857,1.390748157,0.796514009,2.596397081,0.420084558,DB0525910042674_,0.867299259,0.329841845,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,37008,DB00502,10015832,26,1368,59,1813,0.02581708,0.584121163,0.351426111,0.947032501,0.075291463,DB0050210015832_,2.586388523,-0.537646847,NA,10015832,Extrapyramidal disorder,10029205,Nervous system disorders,Nerv,haloperidol,DB00502
,37010,DB00295,10029354,74,14589,82,9520,0.001282166,0.588915963,0.423686948,0.817299631,0.00675047,DB0029510029354_,4.998143173,-0.529471783,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,morphine,DB00295
,37011,DB00441,10029354,109,2165,57,1837,0.003232113,1.622380234,1.159532281,2.290424199,0.01437254,DB0044110029354_,4.242435846,0.483894351,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,gemcitabine,DB00441
,37012,DB00497,10029354,168,19099,159,16216,0.343484757,0.897112545,0.717125547,1.122639686,0.512780452,DB0049710029354_,0.667907495,-0.108573957,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,oxycodone,DB00497
,37014,DB00019,10035664,52,18960,64,9465,1.51725217965674e-06,0.4056185,0.275550391,0.594642279,2.08038463965975e-05,DB0001910035664_,10.78037267,-0.902342216,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pegfilgrastim,DB00019
,37015,DB00433,10035664,355,7301,400,5620,4.08003582318236e-07,0.683189862,0.587982655,0.79356307,6.43913188906325e-06,DB0043310035664_,11.95311683,-0.380982476,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,37018,DB00537,10000059,85,7472,35,4263,0.126335222,1.385536385,0.922562272,2.12087522,0.250563746,DB0053710000059_,1.384041917,0.326087346,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ciprofloxacin,DB00537
,37019,DB00563,10000059,978,45668,231,15117,2.79409560038461e-06,1.401423479,1.211525225,1.626531293,3.55827533217584e-05,DB0056310000059_,10.24364949,0.337488491,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,37020,DB00537,10005483,36,7521,34,4264,0.034293665,0.600292559,0.364551441,0.990535563,0.09399468,DB0053710005483_,2.364517089,-0.510338145,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,ciprofloxacin,DB00537
,37021,DB00563,10005483,96,46550,74,15274,9.34660466005143e-08,0.425673742,0.310890276,0.584829753,1.70076499473487e-06,DB0056310005483_,13.28443241,-0.854082091,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,methotrexate,DB00563
,37022,DB00563,10013710,118,46528,169,15179,9.98009450801809e-35,0.227808351,0.178380576,0.290128331,2.99802039020863e-32,DB0056310013710_,72.58477077,-1.479250571,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,37025,DB00563,10028034,319,46327,47,15301,1.80969831475501e-08,2.241826469,1.645426945,3.115339781,3.82588310661526e-07,DB0056310028034_,14.77630633,0.807290922,NA,10028034,Mouth ulceration,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,37026,DB00537,10035528,60,7497,56,4242,0.008541128,0.606239442,0.413259333,0.890609642,0.031383735,DB0053710035528_,3.461465526,-0.500480253,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,ciprofloxacin,DB00537
,37027,DB00563,10035528,104,46542,104,15244,5.37031736292414e-15,0.327548041,0.247008539,0.434358112,3.27135091273374e-13,DB0056310035528_,28.74840319,-1.116120544,male,10035528,Platelet count decreased,10022891,Investigations,Inv,methotrexate,DB00563
,37029,DB00537,10070863,59,7498,51,4247,0.028541316,0.655322144,0.44193556,0.97458661,0.08147798,DB0053710070863_,2.507422485,-0.422628342,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,ciprofloxacin,DB00537
,37033,DB06403,10020919,423,21048,135,6526,0.762981347,0.971499495,0.796882875,1.190541192,0.868725595,DB0640310020919_,0.140727975,-0.02891453,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,ambrisentan,DB06403
,37034,DB00421,10020646,90,8813,212,5040,7.96888551716271e-32,0.242809589,0.187097551,0.3129215,2.00442254371887e-29,DB0042110020646_,66.07961169,-1.415477728,male,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,spironolactone,DB00421
,37038,DB00682,10005191,60,19399,30,16334,0.019604453,1.683976081,1.06861412,2.705677983,0.06085298,DB0068210005191_,2.799294486,0.521157712,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,37039,DB08877,10010774,74,3215,57,3172,0.185383078,1.280830134,0.891168186,1.849054724,0.330695453,DB0887710010774_,1.10655741,0.24750841,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ruxolitinib,DB08877
,37041,DB00682,10013082,46,19413,23,16341,0.04022737,1.683482847,0.99915613,2.91117818,0.106109023,DB0068210013082_,2.243288195,0.520864771,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,37047,DB08877,10037844,69,3220,62,3167,0.65919168,1.09455197,0.762539459,1.573951324,0.79180136,DB0887710037844_,0.233444727,0.09034512,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ruxolitinib,DB08877
,37054,DB00563,10029148,82,46564,34,15314,0.281075781,0.793184118,0.525527207,1.221040854,0.445011258,DB0056310029148_,0.809655698,-0.231699905,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,methotrexate,DB00563
,37055,DB08895,10029148,99,28015,26,6620,0.648325258,0.899747912,0.578744406,1.44556771,0.783306722,DB0889510029148_,0.244230932,-0.105640652,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,tofacitinib,DB08895
,37056,DB08895,10040753,711,27403,89,6557,8.85673208353241e-10,1.911488621,1.528905438,2.41456605,2.48850029733457e-08,DB0889510040753_,17.50900051,0.647882321,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,37058,DB00987,10010305,29,2075,44,2884,0.811278042,0.916054243,0.550729427,1.50295292,0.898552306,DB0098710010305_,0.106970359,-0.087679699,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,cytarabine,DB00987
,37061,DB04868,10035664,30,1611,35,1481,0.380671549,0.788037841,0.464799222,1.328633626,0.550726906,DB0486810035664_,0.596516226,-0.238209169,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,nilotinib,DB04868
,37067,DB00635,10064684,42,33011,8,23786,0.000139147,3.782769133,1.754036523,9.329414277,0.00105753,DB0063510064684_,6.851818883,1.330456316,female,10064684,Device dislocation,10077536,Product issues,Prod,prednisone,DB00635
,37077,DB08890,10028813,138,1809,20,539,0.002091232,2.055467575,1.265632994,3.504344673,0.010093284,DB0889010028813_,4.595885047,0.720503353,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,linaclotide,DB08890
,37078,DB08890,10047700,63,1884,12,547,0.206517812,1.524020954,0.806869463,3.128131262,0.357101823,DB0889010047700_,1.02973432,0.421352207,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,linaclotide,DB08890
,37080,DB00497,10002855,299,18968,191,16184,0.001890688,1.33566613,1.108807824,1.612080283,0.009290845,DB0049710002855_,4.678725792,0.289430141,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,37083,DB00497,10003983,55,19212,46,16329,1,1.016230508,0.673995136,1.538400349,1,DB0049710003983_,0,0.016100202,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,37085,DB00295,10061822,98,14565,36,9566,0.002491076,1.787857417,1.20764548,2.700233082,0.011627968,DB0029510061822_,4.45434201,0.581017929,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,37086,DB00497,10061822,92,19175,62,16313,0.168559907,1.26238349,0.904294856,1.772609941,0.308967723,DB0049710061822_,1.174518462,0.233001593,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,37097,DB00230,10013786,65,19609,19,8632,0.123751697,1.505968061,0.891181839,2.661299772,0.246749244,DB0023010013786_,1.399382666,0.409435921,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,37101,DB01222,10013786,54,9220,16,5389,0.017611273,1.972570376,1.110885941,3.696249558,0.055944444,DB0122210013786_,2.883396148,0.679337452,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,budesonide,DB01222
,37107,DB00451,10028694,43,47228,7,15412,0.099294159,2.004481157,0.893816773,5.282107333,0.209785946,DB0045110028694_,1.561667572,0.695385253,NA,10028694,Nail disorder,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,37116,DB00572,10029331,56,2846,36,2090,0.594815351,1.142284819,0.735282027,1.79483495,0.74054655,DB0057210029331_,0.300366784,0.133030484,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,atropine,DB00572
,37117,DB00762,10029331,38,1125,40,1329,0.645381931,1.122214287,0.695254943,1.808657922,0.781150925,DB0076210029331_,0.246986902,0.115303776,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,irinotecan,DB00762
,37119,DB01222,10029331,57,9217,36,5369,0.746515631,0.922314718,0.596336662,1.443360763,0.85553676,DB0122210029331_,0.156026218,-0.080868771,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,37120,DB01225,10029331,56,4988,41,4599,0.307082654,1.259302816,0.825030576,1.936571935,0.474148534,DB0122510029331_,0.746234644,0.230558248,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,enoxaparin,DB01225
,37121,DB01409,10029331,41,5990,32,3934,0.47324765,0.841495128,0.516092845,1.383077002,0.639210757,DB0140910029331_,0.447521055,-0.172575056,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,tiotropium,DB01409
,37133,DB00572,10037087,42,2860,19,2107,0.089700205,1.628369565,0.923331445,2.973604659,0.194736311,DB0057210037087_,1.636108885,0.487579247,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,atropine,DB00572
,37135,DB01190,10037087,118,4816,45,2240,0.306606294,1.219581512,0.854811376,1.766552477,0.47363869,DB0119010037087_,0.747310506,0.198507777,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,clindamycin,DB01190
,37136,DB01222,10037087,179,9095,67,5338,0.001675624,1.567983305,1.175321362,2.112972433,0.008413328,DB0122210037087_,4.777938218,0.449790275,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,budesonide,DB01222
,37137,DB01225,10037087,60,4984,43,4597,0.234217449,1.286966426,0.853655366,1.95479352,0.391081543,DB0122510037087_,0.938839192,0.252287841,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,enoxaparin,DB01225
,37138,DB01377,10037087,67,3729,26,2644,0.007989134,1.826968227,1.14229859,3.002795533,0.029754783,DB0137710037087_,3.514765382,0.602657886,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,magnesium oxide,DB01377
,37140,DB00230,10040844,37,19637,19,8632,0.564328951,0.856038778,0.479496875,1.576858621,0.716173546,DB0023010040844_,0.333832759,-0.155439603,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,37141,DB00451,10040844,185,47086,64,15355,0.712362748,0.942644158,0.705378442,1.273818353,0.828937505,DB0045110040844_,0.187610513,-0.059066418,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,37153,DB01222,10043607,58,9216,33,5372,1,1.024488979,0.656094918,1.624081919,1,DB0122210043607_,0,0.024193931,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,budesonide,DB01222
,37154,DB01377,10043607,26,3770,31,2639,0.057569827,0.587161447,0.333976627,1.024518982,0.13887238,DB0137710043607_,1.974199896,-0.53245546,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,magnesium oxide,DB01377
,37155,DB01409,10043607,35,5996,21,3945,0.785534519,1.096572365,0.619745618,1.98553695,0.88367186,DB0140910043607_,0.123669484,0.092189283,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,tiotropium,DB01409
,37177,DB00678,10035664,502,15097,387,10337,0.088849187,0.888176973,0.774447287,1.019187568,0.193335889,DB0067810035664_,1.643326245,-0.118584262,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,losartan,DB00678
,37178,DB00887,10035664,161,2180,103,1712,0.123861738,1.227479966,0.944545003,1.600769894,0.24688097,DB0088710035664_,1.398848963,0.204963259,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,bumetanide,DB00887
,37190,DB00390,10038695,89,4056,60,3241,0.319087236,1.185249629,0.84183108,1.678633241,0.487189335,DB0039010038695_,0.719102454,0.169953409,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,37191,DB00678,10038695,92,15507,64,10660,0.93508703,0.988180713,0.709787553,1.382995313,0.975328369,DB0067810038695_,0.024981076,-0.01188969,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,37192,DB00682,10038695,254,19205,197,16167,0.418766903,1.085409644,0.896450437,1.315678927,0.587792062,DB0068210038695_,0.531382029,0.081957468,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,37194,DB00213,10005750,156,18739,110,13311,1,1.007386577,0.783376584,1.299148859,1,DB0021310005750_,0,0.00735943,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,pantoprazole,DB00213
,37195,DB00635,10005750,284,32769,123,23671,1.49555984438003e-06,1.667867998,1.344239954,2.079444791,2.05385530352816e-05,DB0063510005750_,10.7932068,0.511546163,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,prednisone,DB00635
,37196,DB00715,10005750,52,4791,22,2265,0.708978721,1.117414542,0.664950237,1.937149397,0.826334945,DB0071510005750_,0.190755085,0.111017572,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,paroxetine,DB00715
,37197,DB00814,10005750,76,8211,31,3384,1,1.01038525,0.655899311,1.590940699,1,DB0081410005750_,0,0.010331693,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,meloxicam,DB00814
,37198,DB00820,10005750,70,11845,38,5778,0.607882908,0.898589845,0.596225032,1.37296623,0.750716773,DB0082010005750_,0.286726832,-0.106928583,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,tadalafil,DB00820
,37200,DB01611,10005750,79,11834,9,2352,0.148082717,1.744512389,0.872256196,3.961113596,0.281361445,DB0161110005750_,1.268115156,0.556475083,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,hydroxychloroquine,DB01611
,37201,DB08932,10005750,94,19349,25,6572,0.341330978,1.27708285,0.813557985,2.074450939,0.510476786,DB0893210005750_,0.672410115,0.244578453,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,macitentan,DB08932
,37203,DB14512,10005750,48,4796,15,2397,0.138761355,1.599237906,0.878175482,3.081406155,0.268048962,DB1451210005750_,1.31658562,0.469527207,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,mometasone furoate,DB14512
,37207,DB00451,10017626,63,47208,20,15399,1,1.02752386,0.612725041,1.794908252,1,DB0045110017626_,0,0.027151888,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,levothyroxine,DB00451
,37215,DB08932,10017626,46,19397,10,6587,0.221319075,1.562032161,0.777025779,3.473581378,0.375144894,DB0893210017626_,0.980442943,0.445987641,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,macitentan,DB08932
,37220,DB00814,10028596,30,8257,29,3386,0.001351099,0.424248268,0.245620419,0.733784959,0.007055701,DB0081410028596_,4.953919332,-0.857436458,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,meloxicam,DB00814
,37221,DB00820,10028596,71,11844,64,5752,0.000433726,0.538759994,0.378297158,0.768702948,0.002742236,DB0082010028596_,5.898981615,-0.618485087,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,tadalafil,DB00820
,37223,DB01050,10028596,48,18060,57,9314,2.83150524498186e-05,0.434304221,0.289268656,0.649596198,0.000269709,DB0105010028596_,8.218168076,-0.834010019,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,ibuprofen,DB01050
,37225,DB08932,10028596,151,19292,66,6531,0.08508259,0.774533158,0.575476827,1.052149511,0.186903671,DB0893210028596_,1.677161922,-0.255494808,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,macitentan,DB08932
,37246,DB00230,10022061,62,19612,7,8644,0.000107614,3.904022543,1.785126629,10.11493424,0.000849437,DB0023010022061_,7.070936516,1.362007443,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,37247,DB00230,10024855,177,19497,62,8589,0.138356543,1.257603415,0.935627062,1.709789504,0.267473374,DB0023010024855_,1.318735254,0.229207858,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,37248,DB00230,10025482,1300,18374,294,8357,1.83837451962803e-29,2.011097512,1.765773655,2.29643621,3.91268617396136e-27,DB0023010025482_,60.80557337,0.698680599,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,37250,DB00230,10040753,199,19475,36,8615,1.02809395233314e-07,2.445215495,1.706162117,3.594874869,1.85792021568076e-06,DB0023010040753_,13.19605286,0.894133256,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,pregabalin,DB00230
,37251,DB00230,10047571,271,19403,80,8571,0.001314096,1.496372098,1.160447571,1.947695199,0.00689235,DB0023010047571_,4.977343181,0.403043577,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,pregabalin,DB00230
,37252,DB00230,10052904,190,19484,47,8604,0.000220083,1.785131212,1.289759939,2.514745158,0.001561792,DB0023010052904_,6.461921689,0.579491921,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,37255,DB00230,10068319,105,19569,26,8625,0.007526012,1.77991224,1.14864311,2.852125858,0.02836876,DB0023010068319_,3.562466732,0.57656406,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,37256,DB00115,10003988,479,17946,214,10258,0.003051846,1.279430039,1.084681502,1.513092896,0.01371361,DB0011510003988_,4.28936652,0.246414697,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,37257,DB00678,10003988,326,15273,184,10540,0.032382541,1.222673229,1.015596206,1.475546876,0.089938123,DB0067810003988_,2.408633365,0.201039633,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,37258,DB01268,10003988,60,2083,86,3044,0.932003078,1.019552227,0.717154296,1.441560041,0.972941773,DB0126810003988_,0.027431041,0.019363538,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sunitinib,DB01268
,37260,DB11089,10003988,252,9923,170,8237,0.042428781,1.230474221,1.006623922,1.507092848,0.110545721,DB1108910003988_,2.202326081,0.207399641,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,37268,DB01268,10018388,68,2075,74,3056,0.083089592,1.353255351,0.954329074,1.916515108,0.183599675,DB0126810018388_,1.694997571,0.302513061,NA,10018388,Glossodynia,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,37271,DB01268,10019211,130,2013,97,3033,2.63023782332468e-07,2.019053761,1.530447386,2.670810015,4.34133759410293e-06,DB0126810019211_,12.34732806,0.702628967,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sunitinib,DB01268
,37272,DB09104,10019211,39,1011,15,857,0.008348787,2.203047411,1.177772344,4.333148663,0.030804024,DB0910410019211_,3.480109956,0.789841589,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,magnesium hydroxide,DB09104
,37273,DB11089,10019211,385,9790,162,8245,4.03497794799183e-14,2.001376428,1.657444756,2.425517197,2.17112375359192e-12,DB1108910019211_,26.85577622,0.693835158,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,docusate,DB11089
,37274,DB00590,10020772,22,754,38,1914,0.191798827,1.469412718,0.821921701,2.568111126,0.338912969,DB0059010020772_,1.082011933,0.38486281,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,doxazosin,DB00590
,37276,DB11089,10020772,138,10037,108,8299,0.699083231,1.056529087,0.813911417,1.374344699,0.819068966,DB1108910020772_,0.199586991,0.054989089,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,docusate,DB11089
,37285,DB00331,10029412,33,24913,36,20716,0.277393526,0.762248708,0.460399041,1.258222619,0.440974256,DB0033110029412_,0.818768782,-0.271482388,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,metformin,DB00331
,37302,DB08908,10024855,76,10597,16,3263,0.176772452,1.462546469,0.843825344,2.691205067,0.319751155,DB0890810024855_,1.140212226,0.380179074,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,37311,DB00115,10013950,122,18303,48,10424,0.030615666,1.447522704,1.027563631,2.067863707,0.086053871,DB0011510013950_,2.452781773,0.369853615,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,37312,DB00169,10013950,261,38430,120,18055,0.868810126,1.021863358,0.819480489,1.280216517,0.94160196,DB0016910013950_,0.060172642,0.021627782,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,37313,DB00338,10013950,202,33472,151,22121,0.252656335,0.884096354,0.711971893,1.099770469,0.412899264,DB0033810013950_,0.884551628,-0.123189225,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,37314,DB00115,10013952,90,18335,43,10429,0.367192303,1.190480731,0.818293443,1.755855921,0.536814131,DB0011510013952_,0.622103369,0.174357201,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,37315,DB00169,10013952,184,38507,69,18106,0.120042856,1.253830513,0.945308166,1.679501193,0.241441553,DB0016910013952_,1.421127852,0.226203276,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,37316,DB00455,10013952,49,9352,13,5105,0.02264349,2.057428233,1.097852164,4.137535796,0.06806772,DB0045510013952_,2.687252192,0.721456772,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,37318,DB13961,10013952,48,9409,27,6387,0.480256415,1.20675302,0.737163608,2.013720794,0.645078434,DB1396110013952_,0.438383366,0.187933298,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,37319,DB00338,10014020,62,33612,8,22264,2.37260330450435e-07,5.133344586,2.449227884,12.41664153,3.95709884891477e-06,DB0033810014020_,12.43999942,1.635757413,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,omeprazole,DB00338
,37332,DB00169,10043528,71,38620,24,18151,0.186343422,1.390410261,0.864179412,2.310862674,0.331879042,DB0016910043528_,1.102984707,0.329598855,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,37333,DB00338,10043528,54,33620,21,22251,0.044086633,1.701851516,1.010690661,2.967509708,0.113754505,DB0033810043528_,2.173712616,0.531716785,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,37335,DB01075,10043528,107,19841,48,11049,0.239533199,1.241406539,0.874477606,1.784846299,0.397360356,DB0107510043528_,0.922911713,0.216245042,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,37356,DB00761,10013952,91,15216,26,8599,0.001406563,1.977898551,1.26606071,3.190019206,0.00728718,DB0076110013952_,4.92163865,0.682034943,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,37357,DB06605,10013952,39,14034,25,13008,0.168559768,1.445926994,0.852690165,2.494320088,0.308967723,DB0660510013952_,1.174518462,0.368750634,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,37359,DB00761,10064355,46,15261,37,8588,0.109614675,0.699662843,0.443572063,1.110278802,0.225500644,DB0076110064355_,1.489432264,-0.357156712,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,37360,DB00983,10064355,134,3367,78,1662,0.264468814,0.848042174,0.63256105,1.143260972,0.426423923,DB0098310064355_,0.852321304,-0.164824911,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,formoterol,DB00983
,37361,DB01222,10064355,65,9209,20,5385,0.012598018,1.900373549,1.134898319,3.316315715,0.042804926,DB0122210064355_,3.151102082,0.642050472,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,budesonide,DB01222
,37362,DB06605,10064355,70,14003,49,12984,0.141520223,1.324597433,0.90568533,1.950569552,0.271959283,DB0660510064355_,1.30210292,0.281108589,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,37363,DB00115,10069327,53,18372,20,10452,0.142899291,1.507588936,0.885733842,2.664057974,0.273890874,DB0011510069327_,1.295025522,0.410511643,NA,10069327,Product quality issue,10077536,Product issues,Prod,cyanocobalamin,DB00115
,37364,DB00761,10069327,37,15270,16,8609,0.474075038,1.303750357,0.70712246,2.511640474,0.63979283,DB0076110069327_,0.446610858,0.265245001,NA,10069327,Product quality issue,10077536,Product issues,Prod,potassium chloride,DB00761
,37366,DB00115,10008531,193,18232,83,10389,0.032451033,1.324995995,1.01805687,1.737089943,0.090085589,DB0011510008531_,2.406995074,0.281409437,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,37367,DB01137,10008531,56,7716,59,5534,0.045813675,0.680775508,0.462905849,1.000133023,0.117112807,DB0113710008531_,2.144617647,-0.384522677,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,37369,DB08896,10013968,49,774,61,979,1,1.016028206,0.674603932,1.523626154,1,DB0889610013968_,0,0.015901111,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,regorafenib,DB08896
,37370,DB00169,10015150,365,38326,128,18047,0.004163948,1.342783079,1.094048584,1.656698317,0.017647431,DB0016910015150_,4.037165069,0.294744385,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,37371,DB00230,10015150,123,19551,36,8615,0.03074305,1.5055253,1.030039476,2.249966322,0.086365743,DB0023010015150_,2.449164174,0.409141874,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,37372,DB01137,10015150,58,7714,25,5568,0.033540491,1.674520658,1.029578867,2.79742873,0.092436362,DB0113710015150_,2.381234848,0.51552695,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,levofloxacin,DB01137
,37373,DB08896,10015150,40,783,31,1009,0.038493884,1.662263285,1.003841001,2.775628593,0.102623027,DB0889610015150_,2.276692936,0.508180098,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,regorafenib,DB08896
,37374,DB00115,10028391,116,18309,59,10413,0.528330284,1.118206078,0.809685194,1.558354666,0.685768821,DB0011510028391_,0.377214703,0.111725685,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,37375,DB00230,10028391,158,19516,51,8600,0.059212154,1.365233159,0.988732507,1.912616625,0.142006521,DB0023010028391_,1.951882297,0.311325227,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,37376,DB01137,10028391,49,7723,22,5571,0.070278354,1.606589619,0.95192731,2.793789296,0.161771305,DB0113710028391_,1.821571641,0.474113683,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,37378,DB00115,10028836,134,18291,49,10423,0.006918915,1.558323542,1.114538834,2.210159261,0.026553321,DB0011510028836_,3.628600466,0.443610591,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,37379,DB00230,10028836,205,19469,55,8596,0.000878472,1.645648336,1.215193005,2.261112238,0.004952413,DB0023010028836_,5.307880363,0.498134432,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,37380,DB01137,10028836,33,7739,19,5574,0.483257572,1.25093611,0.689945507,2.33107405,0.647467931,DB0113710028836_,0.434686014,0.223892159,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,37382,DB08896,10033425,110,713,135,905,0.836047046,1.034229458,0.781315154,1.366806737,0.915283392,DB0889610033425_,0.088521544,0.033656664,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,regorafenib,DB08896
,37383,DB00115,10037660,378,18047,242,10230,0.151006441,0.885422703,0.75007007,1.046735521,0.28528745,DB0011510037660_,1.254258009,-0.121690118,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,37384,DB00230,10037660,247,19427,94,8557,0.237387274,1.157390093,0.907805346,1.485889707,0.394756872,DB0023010037660_,0.929485218,0.14616755,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,37385,DB08896,10037660,74,749,42,998,1.73239252862968e-05,2.346572861,1.565456135,3.556530792,0.000175984,DB0889610037660_,8.645115772,0.852955907,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,regorafenib,DB08896
,37386,DB00108,10021789,127,10067,44,3251,0.720095785,0.932109745,0.655089614,1.348193208,0.834776295,DB0010810021789_,0.1805915,-0.070304719,NA,10021789,Infection,10021881,Infections and infestations,Infec,natalizumab,DB00108
,37389,DB00060,10016334,39,9469,11,2454,0.860641466,0.918838814,0.460673308,1.992215772,0.934463553,DB0006010016334_,0.067782654,-0.084644565,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,37395,DB01255,10013573,49,2084,20,1558,0.026277678,1.831330656,1.063590383,3.266681932,0.076376267,DB0125510013573_,2.572083276,0.605042837,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lisdexamfetamine,DB01255
,37396,DB01306,10013573,118,4090,116,3750,0.642163944,0.932709374,0.712800674,1.220602086,0.778672291,DB0130610013573_,0.250165,-0.069661622,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,insulin aspart,DB01306
,37397,DB01255,10013710,26,2107,34,1544,0.034307557,0.560474358,0.321494046,0.96653031,0.09401805,DB0125510013710_,2.364268492,-0.578971786,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,lisdexamfetamine,DB01255
,37400,DB01255,10020642,23,2110,34,1544,0.00998156,0.495098118,0.277259947,0.869320187,0.035517165,DB0125510020642_,3.337739172,-0.702999317,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,lisdexamfetamine,DB01255
,37401,DB01306,10020642,34,4174,27,3839,0.60836774,1.158171026,0.676871554,1.999728263,0.751034851,DB0130610020642_,0.286303222,0.146842059,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,insulin aspart,DB01306
,37404,DB00126,10027175,134,10037,59,5886,0.071653501,1.33186949,0.971728139,1.844409771,0.164153247,DB0012610027175_,1.806954855,0.286583587,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,37405,DB00697,10027175,98,5998,21,1785,0.187854018,1.388726647,0.857285106,2.35044339,0.333913296,DB0069710027175_,1.096873913,0.328387246,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,37406,DB14513,10027175,102,7075,32,3532,0.02096441,1.591208782,1.057942883,2.45226548,0.064153854,DB1451310027175_,2.746471112,0.464493967,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,37407,DB00060,10028335,44,9464,13,2452,0.625647202,0.876897013,0.46297978,1.777552828,0.765228204,DB0006010028335_,0.267581184,-0.131365724,NA,10028335,Muscle spasticity,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,37416,DB00126,10048393,81,10090,20,5925,0.000258074,2.378105932,1.441911922,4.101516692,0.001784419,DB0012610048393_,6.328662315,0.866304344,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,37417,DB00697,10048393,176,5920,36,1770,0.038270585,1.461619728,1.012057934,2.163104767,0.102167615,DB0069710048393_,2.281140532,0.379545223,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,37418,DB14513,10048393,46,7131,6,3558,0.000543892,3.824687041,1.627368208,10.96960121,0.003308538,DB1451310048393_,5.711248843,1.341476644,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,37419,DB00126,10057668,48,10123,18,5927,0.124654321,1.561288042,0.890689986,2.854736702,0.248053511,DB0012610057668_,1.394110786,0.445511149,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,37421,DB01373,10057668,59,22661,15,7366,0.49844313,1.278517785,0.715583884,2.428217072,0.660278577,DB0137310057668_,0.415093446,0.245701426,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,calcium,DB01373
,37429,DB00421,10000060,170,8733,57,5195,0.000130202,1.77410591,1.304289474,2.443893762,0.000998663,DB0042110000060_,6.909093117,0.573296584,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,37430,DB00451,10000060,401,46870,107,15312,0.070052279,1.224317363,0.986035336,1.531223588,0.161342751,DB0045110000060_,1.824224288,0.202383434,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,37431,DB00455,10000060,88,9313,20,5098,0.000162247,2.408463715,1.467312693,4.138539307,0.001205729,DB0045510000060_,6.720671181,0.878989081,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,37433,DB00559,10000060,105,9554,53,3253,0.021737109,0.674569624,0.479100339,0.959555144,0.066022638,DB0055910000060_,2.717757593,-0.393680386,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,37434,DB00695,10000060,329,27720,193,20335,0.01425482,1.250510501,1.042751154,1.50299853,0.047261346,DB0069510000060_,3.052062536,0.223551869,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,37435,DB00788,10000060,60,9296,28,5033,0.576094436,1.160148633,0.728141899,1.890108794,0.725446856,DB0078810000060_,0.32096746,0.148548128,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,37437,DB01068,10000060,103,13660,38,6802,0.127057008,1.349713664,0.920919457,2.015427383,0.251497669,DB0106810000060_,1.380321557,0.299892469,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,37439,DB00455,10013968,482,8919,234,4884,0.148671529,1.127963462,0.95897994,1.329523165,0.28216406,DB0045510013968_,1.265266606,0.12041376,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,37440,DB00484,10013968,85,2422,31,1749,0.001079071,1.97972913,1.291493701,3.10590339,0.005867479,DB0048410013968_,5.138330251,0.682960032,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,brimonidine,DB00484
,37442,DB01142,10013968,64,1676,23,761,0.409246486,1.263313066,0.766817302,2.149335677,0.578646793,DB0114210013968_,0.547063017,0.233737688,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxepin,DB01142
,37447,DB00695,10015916,53,27996,26,20502,0.110086596,1.492790296,0.916703918,2.487718114,0.226188242,DB0069510015916_,1.486387696,0.400647051,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,furosemide,DB00695
,37452,DB00484,10048959,37,2470,19,1761,0.276251573,1.388283044,0.775166282,2.564760801,0.439690732,DB0048410048959_,0.821683681,0.328067764,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,brimonidine,DB00484
,37453,DB00788,10048959,202,9154,74,4987,0.003353832,1.487088509,1.13127213,1.972617947,0.014796154,DB0078810048959_,4.213387986,0.396820187,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,37456,DB01068,10048959,185,13578,76,6764,0.165260789,1.212585841,0.9220111,1.608064478,0.304490827,DB0106810048959_,1.189114317,0.192755138,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,37472,DB00567,10016173,143,4376,72,2009,0.550644727,0.911829876,0.678622554,1.234103049,0.704727659,DB0056710016173_,0.34994385,-0.092301845,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,cephalexin,DB00567
,37473,DB00794,10016173,56,780,33,576,0.375477725,1.252953715,0.78905041,2.017057761,0.545332971,DB0079410016173_,0.606358714,0.225503736,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,primidone,DB00794
,37474,DB00060,10019196,55,9453,10,2455,0.357235818,1.428333865,0.719733785,3.14751802,0.526932855,DB0006010019196_,0.640682149,0.356508636,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,interferon beta-1a,DB00060
,37477,DB00567,10020937,61,4458,18,2063,0.112580824,1.568156683,0.911721449,2.827064005,0.229946923,DB0056710020937_,1.469906765,0.449900842,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,cephalexin,DB00567
,37488,DB00051,10041349,66,25665,29,11391,1,1.010107687,0.643077884,1.622625754,1,DB0005110041349_,0,0.010056946,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,37495,DB00005,10028245,75,128007,32,42387,0.220621445,0.776088041,0.506623187,1.213726958,0.37423992,DB0000510028245_,0.982858191,-0.25348931,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,37496,DB00005,10047920,70,128012,16,42403,0.211955221,1.449153128,0.833056265,2.673584497,0.363729384,DB0000510047920_,1.011345139,0.370979336,NA,10047920,Wheelchair user,10041244,Social circumstances,SocCi,etanercept,DB00005
,37497,DB05259,10022052,291,10979,48,2680,0.012270774,1.47982018,1.083903574,2.058594258,0.041896121,DB0525910022052_,3.172562024,0.39192058,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,37498,DB00682,10010264,486,18973,231,16133,1.47208891183205e-13,1.788937811,1.524168238,2.104468025,7.38432386402777e-12,DB0068210010264_,25.63166176,0.581622042,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,37499,DB00203,10012378,87,13791,81,8857,0.017290744,0.68983302,0.503155905,0.946602396,0.055129453,DB0020310012378_,2.898071175,-0.371305711,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,sildenafil,DB00203
,37501,DB00820,10012378,103,11812,57,5759,0.44727949,0.881032956,0.630382971,1.241972492,0.615055635,DB0082010012378_,0.486042552,-0.126660247,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,tadalafil,DB00820
,37502,DB00559,10022437,113,9546,25,3281,0.049168377,1.553437781,0.998295472,2.506056878,0.123425726,DB0055910022437_,2.09211571,0.440470398,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,bosentan,DB00559
,37503,DB00820,10022437,236,11679,115,5701,1,1.001750352,0.796370256,1.265961114,1,DB0082010022437_,0,0.001748822,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,tadalafil,DB00820
,37509,DB00480,10012601,103,67325,170,67492,5.93123917183559e-05,0.607391115,0.470711693,0.780535992,0.00051081,DB0048010012601_,7.579512968,-0.498582355,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,37510,DB00480,10061016,246,67182,241,67421,0.820471026,1.024382448,0.853876361,1.229082561,0.904351949,DB0048010061016_,0.10053667,0.024089941,NA,10061016,Blood test abnormal,10022891,Investigations,Inv,lenalidomide,DB00480
,37512,DB06186,10001551,37,2172,55,3591,0.664802991,1.112206982,0.710175623,1.724443996,0.795970875,DB0618610001551_,0.228192683,0.106346313,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,ipilimumab,DB06186
,37513,DB09035,10001551,51,4675,73,6617,1,0.988842433,0.676150942,1.436650344,1,DB0903510001551_,0,-0.011220279,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,nivolumab,DB09035
,37514,DB06186,10020635,20,2189,53,3593,0.069186543,0.619439656,0.349760469,1.057018356,0.159867108,DB0618610020635_,1.833412382,-0.47893999,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,ipilimumab,DB06186
,37515,DB09035,10020635,31,4695,87,6603,0.000679597,0.501158302,0.320799963,0.76452355,0.003994009,DB0903510020635_,5.522959677,-0.690833256,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,nivolumab,DB09035
,37516,DB00213,10001497,54,18841,37,13384,0.915403224,1.036752585,0.669464181,1.621401689,0.962143444,DB0021310001497_,0.03859173,0.036093313,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,37517,DB00338,10001497,112,33562,78,22194,0.766608038,0.949552524,0.704493988,1.285256968,0.871552434,DB0033810001497_,0.13747925,-0.051764432,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,37520,DB00656,10001497,94,11919,98,6521,1.32016161174197e-05,0.524780829,0.390544624,0.704863829,0.000138608,DB0065610001497_,8.883862621,-0.644774573,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,37521,DB00722,10001497,77,25326,88,25944,0.532856263,0.896354803,0.651113122,1.231753582,0.689634254,DB0072210001497_,0.371593889,-0.109418959,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,37523,DB00999,10001497,56,21374,30,12209,0.823107625,1.066258778,0.672214966,1.722091248,0.906103528,DB0099910001497_,0.09860171,0.064156053,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,37527,DB00656,10005483,28,11985,30,6589,0.012840384,0.51312358,0.295132813,0.889651505,0.043457092,DB0065610005483_,3.135981226,-0.667238567,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,trazodone,DB00656
,37528,DB00987,10005483,21,2083,31,2897,0.8882884,0.942144714,0.512993575,1.698356132,0.953707237,DB0098710005483_,0.047398534,-0.059596392,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,cytarabine,DB00987
,37529,DB00999,10005483,123,21307,110,12129,0.00077461,0.636563865,0.48767839,0.831726045,0.004452844,DB0099910005483_,5.414212333,-0.451670527,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,37532,DB01377,10005483,42,3754,27,2643,0.806056427,1.095193984,0.657751935,1.852118647,0.895107444,DB0137710005483_,0.110811519,0.090931502,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,magnesium oxide,DB01377
,37533,DB00338,10005851,48,33626,40,22232,0.278185981,0.793398093,0.510447846,1.239185748,0.441980084,DB0033810005851_,0.816490457,-0.231430174,NA,10005851,Blood urea increased,10022891,Investigations,Inv,omeprazole,DB00338
,37536,DB00999,10005851,32,21398,30,12209,0.063299087,0.608644965,0.357961093,1.037365903,0.149482639,DB0099910005851_,1.90057502,-0.496520162,NA,10005851,Blood urea increased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,37540,DB00999,10011906,540,20890,435,11804,8.76960866567526e-08,0.701481913,0.615835058,0.799333703,1.60851674481384e-06,DB0099910011906_,13.34019808,-0.354560162,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,37541,DB01005,10011906,71,1024,83,784,0.01403089,0.655087453,0.46371174,0.923459351,0.046671976,DB0100510011906_,3.064611389,-0.422986535,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,hydroxyurea,DB01005
,37543,DB01377,10011906,155,3641,162,2508,0.000346637,0.65911769,0.522210772,0.831668197,0.0022767,DB0137710011906_,6.085028063,-0.416853171,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,37555,DB00584,10018884,31,2050,31,1843,0.702046314,0.899049175,0.526288305,1.535806936,0.821186274,DB0058410018884_,0.197005308,-0.106417547,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,enalapril,DB00584
,37556,DB00999,10018884,188,21242,96,12143,0.386295201,1.119495482,0.869945572,1.448336122,0.55644715,DB0099910018884_,0.586183082,0.112878122,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,37558,DB01377,10018884,62,3734,45,2625,0.921208612,0.968565708,0.647004601,1.460014368,0.965093784,DB0137710018884_,0.035529997,-0.031938953,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,magnesium oxide,DB01377
,37561,DB01377,10021097,104,3692,102,2568,0.017454885,0.709248135,0.531901641,0.945910409,0.05553491,DB0137710021097_,2.890743449,-0.343549836,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,magnesium oxide,DB01377
,37563,DB00656,10035528,64,11949,45,6574,0.228346311,0.782494208,0.525466508,1.173944668,0.383850784,DB0065610035528_,0.957501386,-0.245268758,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,trazodone,DB00656
,37564,DB00722,10035528,215,25188,193,25839,0.196150121,1.142777583,0.935786569,1.396353152,0.344409215,DB0072210035528_,1.065924751,0.133461776,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,lisinopril,DB00722
,37565,DB00999,10035528,129,21301,126,12113,1.97570108705126e-05,0.582237864,0.45140516,0.751016834,0.000197697,DB0099910035528_,8.528775407,-0.540876213,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,37567,DB01377,10035528,48,3748,49,2621,0.076815428,0.685089724,0.448871531,1.045031855,0.172885637,DB0137710035528_,1.755124959,-0.378205466,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,magnesium oxide,DB01377
,37578,DB00213,10049438,59,18836,31,13390,0.198644375,1.352938181,0.861176312,2.163710495,0.3474355,DB0021310049438_,1.057176244,0.302278658,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,37579,DB00338,10049438,72,33602,48,22224,1,0.992082729,0.678818708,1.461317408,1,DB0033810049438_,0,-0.007948779,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,37583,DB00722,10049438,38,25365,40,25992,0.910403004,0.973478817,0.607540941,1.557452096,0.95959671,DB0072210049438_,0.041242177,-0.026879214,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,37590,DB00108,10019196,46,10148,12,3283,0.645729309,1.240103897,0.645491004,2.575137488,0.781373487,DB0010810019196_,0.246702026,0.215195164,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,natalizumab,DB00108
,37591,DB00374,10006784,52,17664,20,5704,0.493861479,0.839563286,0.492211942,1.486036379,0.656558632,DB0037410006784_,0.42074328,-0.17487342,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,37593,DB00682,10006784,66,19393,32,16332,0.010814963,1.736923525,1.12177138,2.740104018,0.037905367,DB0068210006784_,3.272662576,0.552115459,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,37599,DB01225,10022052,65,4979,34,4606,0.008243477,1.768436967,1.148263994,2.767874734,0.030507539,DB0122510022052_,3.489781439,0.570096087,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,37602,DB01225,10022086,81,4963,34,4606,6.91886604944983e-05,2.210706289,1.460841715,3.411697334,0.000581402,DB0122510022086_,7.450068963,0.793312052,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,37603,DB01174,10013709,114,825,96,696,1,1.001817152,0.742350184,1.354035303,1,DB0117410013709_,0,0.001815503,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,phenobarbital,DB01174
,37604,DB01076,10028334,459,25288,341,25242,4.06496742983109e-05,1.343579972,1.164083615,1.55196336,0.000369885,DB0107610028334_,7.902318436,0.295337673,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,37606,DB00115,10012601,52,18373,43,10429,0.069739265,0.686469036,0.449105286,1.054024269,0.16082999,DB0011510012601_,1.827407437,-0.376194159,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,cyanocobalamin,DB00115
,37607,DB00169,10012601,148,38543,69,18106,1,1.007605165,0.751798922,1.361857292,1,DB0016910012601_,0,0.007576392,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,37608,DB00695,10012601,113,27936,90,20438,0.569267703,0.918567704,0.689771405,1.226230762,0.720198377,DB0069510012601_,0.328228582,-0.084939666,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,37610,DB01234,10012601,59,31566,123,32765,7.06161913820867e-06,0.497902272,0.358517171,0.684746746,8.00408189080703e-05,DB0123410012601_,9.432973817,-0.697351463,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,37611,DB01373,10012601,65,22655,37,7344,0.007764413,0.569494878,0.374351715,0.87804588,0.029080591,DB0137310012601_,3.537684313,-0.563005491,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,calcium,DB01373
,37612,DB01162,10012735,8,265,95,1607,0.07735065,0.510808636,0.211841048,1.064567867,0.173852278,DB0116210012735_,1.749549315,-0.671760248,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,terazosin,DB01162
,37614,DB00555,10001488,49,6998,38,3448,0.039396993,0.635354216,0.406603027,0.999621592,0.104437494,DB0055510001488_,2.259166535,-0.453572615,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,37615,DB00656,10001488,30,11983,66,6553,4.68322346775293e-11,0.248592212,0.155666768,0.388724832,1.61440693573621e-09,DB0065610001488_,20.24429817,-1.391941427,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,37616,DB01018,10001488,23,389,75,704,0.014870388,0.555247695,0.326501388,0.913052874,0.048968697,DB0101810001488_,3.016574014,-0.588340968,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,guanfacine,DB01018
,37620,DB00776,10012378,48,1857,31,1308,0.730304886,1.090616997,0.675959034,1.782824154,0.843097434,DB0077610012378_,0.170672747,0.086743588,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,oxcarbazepine,DB00776
,37621,DB06218,10012378,42,1652,46,1390,0.233851344,0.768308576,0.49017931,1.201341437,0.390631539,DB0621810012378_,0.939990519,-0.263563834,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,lacosamide,DB06218
,37624,DB00776,10042458,36,1869,18,1321,0.265877417,1.413443515,0.777988754,2.656356504,0.427973171,DB0077610042458_,0.84869477,0.346028936,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,oxcarbazepine,DB00776
,37628,DB00706,10040753,18,1057,94,15831,0.000223488,2.867709919,1.62293948,4.805067499,0.001581259,DB0070610040753_,6.449533791,1.053513773,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,tamsulosin,DB00706
,37637,DB08934,10028334,44,4445,49,6155,0.29385548,1.243371211,0.806833828,1.910973366,0.459570457,DB0893410028334_,0.777463015,0.217826409,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,sofosbuvir,DB08934
,37640,DB06413,10053762,32,1524,20,654,0.220942226,0.68673648,0.377677357,1.277069625,0.37461483,DB0641310053762_,0.9818569,-0.375804641,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,armodafinil,DB06413
,37643,DB00575,10007515,50,5194,55,3774,0.036829207,0.660596127,0.440183925,0.989368093,0.099231787,DB0057510007515_,2.310296885,-0.414612629,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,clonidine,DB00575
,37644,DB01156,10007515,273,13349,166,6162,0.00693277,0.759133939,0.622171485,0.928585535,0.026596783,DB0115610007515_,3.626965007,-0.27557705,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,bupropion,DB01156
,37645,DB00422,10010144,98,3337,82,2867,0.879712083,1.026794437,0.754501749,1.40031082,0.949457398,DB0042210010144_,0.051864617,0.026441752,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,methylphenidate,DB00422
,37646,DB00575,10010144,235,5009,233,3596,0.000754723,0.724107686,0.598363708,0.876259285,0.004355192,DB0057510010144_,5.436386653,-0.322815159,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,clonidine,DB00575
,37647,DB01156,10010144,1786,11836,1089,5239,3.75148836433013e-14,0.72592331,0.668262441,0.788820009,2.03525018898694e-12,DB0115610010144_,26.92040236,-0.320310903,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,37651,DB00203,10061105,98,13780,40,8898,0.014180041,1.581978708,1.08357055,2.348554336,0.047072793,DB0020310061105_,3.056060095,0.45867641,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,37659,DB00099,10011224,48,2337,56,1899,0.072792595,0.696563815,0.461314291,1.04827905,0.166190685,DB0009910011224_,1.794619447,-0.361595868,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,filgrastim,DB00099
,37660,DB00773,10011224,46,2277,49,2778,0.533455386,1.145298727,0.745915606,1.755916738,0.690188759,DB0077310011224_,0.370790155,0.1356655,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etoposide,DB00773
,37662,DB00099,10016288,85,2300,118,1837,0.000159894,0.575415397,0.427154562,0.772427783,0.001191778,DB0009910016288_,6.732309001,-0.55266307,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,filgrastim,DB00099
,37663,DB00773,10016288,255,2068,390,2437,0.002320857,0.770554541,0.648371197,0.91465446,0.010979794,DB0077310016288_,4.511698636,-0.26064484,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,etoposide,DB00773
,37664,DB01033,10016288,129,1053,193,1111,0.004081011,0.705311723,0.551001164,0.900624798,0.017365707,DB0103310016288_,4.053257876,-0.349115414,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,mercaptopurine,DB01033
,37668,DB00563,10062355,169,46477,48,15300,0.387214639,1.159035811,0.83620626,1.633183323,0.557267673,DB0056310062355_,0.584709593,0.147588462,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,37686,DB00695,10007617,96,27953,116,20412,0.000276494,0.604344276,0.455981577,0.799412079,0.001888926,DB0069510007617_,6.271747093,-0.503611251,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,furosemide,DB00695
,37687,DB00999,10007617,42,21388,44,12195,0.0049554,0.544299342,0.347757242,0.850748164,0.020326021,DB0099910007617_,3.895853409,-0.608255923,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,37689,DB01050,10007617,112,17996,52,9319,0.563372302,1.115331833,0.795020048,1.582648001,0.71535668,DB0105010007617_,0.334974008,0.109151968,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,ibuprofen,DB01050
,37690,DB11089,10007617,30,10145,32,8375,0.371149165,0.77394957,0.453899427,1.316379709,0.540764159,DB1108910007617_,0.614772031,-0.256248563,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,docusate,DB11089
,37695,DB00046,10008190,71,5388,68,4624,0.549223019,0.896075742,0.631854366,1.271652596,0.703578901,DB0004610008190_,0.351575254,-0.109730336,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,insulin lispro,DB00046
,37696,DB00697,10020772,99,5997,29,1777,1,1.011557761,0.660353971,1.593131475,1,DB0069710020772_,0,0.011491481,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,tizanidine,DB00697
,37697,DB06413,10020772,52,1504,17,657,0.352274206,1.336087474,0.753353454,2.483930474,0.522058678,DB0641310020772_,0.649975288,0.289745547,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,armodafinil,DB06413
,37698,DB06637,10020772,61,6101,15,2004,0.351832604,1.335720393,0.747997314,2.536582018,0.521567875,DB0663710020772_,0.65091586,0.289470767,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,dalfampridine,DB06637
,37699,DB08868,10020772,182,9020,47,2464,0.807302776,1.05777145,0.76122498,1.495298293,0.895894857,DB0886810020772_,0.10993222,0.05616429,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,fingolimod,DB08868
,37704,DB00697,10046571,218,5878,41,1765,0.005307022,1.596434273,1.133914684,2.296730722,0.021454179,DB0069710046571_,3.841835819,0.467772563,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,tizanidine,DB00697
,37706,DB06637,10046571,848,5314,141,1878,1.75326423396336e-17,2.125281261,1.761839854,2.578337235,1.43342302922945e-15,DB0663710046571_,34.17871108,0.753904152,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,dalfampridine,DB06637
,37707,DB08868,10046571,261,8941,48,2463,0.009288084,1.497811659,1.093552179,2.089614453,0.033546861,DB0886810046571_,3.394811996,0.404005149,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,fingolimod,DB08868
,37710,DB00381,10035528,230,29130,191,22696,0.521781815,0.938232922,0.770418338,1.143631101,0.680482388,DB0038110035528_,0.384953338,-0.063757043,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,amlodipine,DB00381
,37711,DB01118,10035528,29,3034,50,4659,0.645572065,0.890637849,0.54210956,1.438739107,0.781255144,DB0111810035528_,0.246853493,-0.115817388,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,amiodarone,DB01118
,37721,DB01224,10047942,32,8076,19,5898,0.570383009,1.229980868,0.675532531,2.299218514,0.72095008,DB0122410047942_,0.327185382,0.206998615,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,quetiapine,DB01224
,37724,DB00184,10013709,99,1195,54,928,0.042868034,1.423491847,0.999672926,2.045026886,0.111452648,DB0018410013709_,2.194155459,0.3531129,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,nicotine,DB00184
,37726,DB00404,10000081,278,19614,98,9764,0.003419783,1.412132866,1.116289305,1.798745151,0.015041666,DB0040410000081_,4.196931163,0.345101233,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,37727,DB01233,10000081,98,3323,45,1681,0.653607823,1.101657788,0.762428591,1.612928542,0.787733861,DB0123310000081_,0.238594986,0.096816125,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,metoclopramide,DB01233
,37732,DB00555,10003988,107,6940,28,3458,0.00169697,1.904003382,1.243304562,3.005019629,0.008493734,DB0055510003988_,4.76842656,0.643958713,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lamotrigine,DB00555
,37733,DB01233,10003988,75,3346,33,1693,0.538160086,1.149906095,0.7505263,1.796020029,0.694140288,DB0123310003988_,0.365081195,0.139680283,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,metoclopramide,DB01233
,37739,DB00404,10027951,43,19849,13,9849,0.120246422,1.641239498,0.865784805,3.32828193,0.241697424,DB0040410027951_,1.420068649,0.495451748,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,37740,DB00425,10027951,38,12657,14,7470,0.150801263,1.601901172,0.847753931,3.202949695,0.285053483,DB0042510027951_,1.255078456,0.471191157,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,37743,DB00555,10033371,207,6840,50,3436,1.13997566825246e-06,2.079557537,1.515946989,2.90002833,1.6075247017176e-05,DB0055510033371_,11.03822992,0.732155148,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,37744,DB01233,10033371,140,3281,32,1694,1.18090790739291e-05,2.258530511,1.521507094,3.444335973,0.000125567,DB0123310033371_,8.982671015,0.814714385,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,37751,DB01233,10047895,73,3348,57,1669,0.014188574,0.638480565,0.442989098,0.9241565,0.047086254,DB0123310047895_,3.055774166,-0.448664042,NA,10047895,Weight decreased,10022891,Investigations,Inv,metoclopramide,DB01233
,37753,DB00404,10056819,67,19825,15,9847,0.00324894,2.218524319,1.253257828,4.184621943,0.014429059,DB0040410056819_,4.238511097,0.796842254,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,37763,DB00425,10061428,207,12488,166,7318,0.003428421,0.730770586,0.591649038,0.903684898,0.015073322,DB0042510061428_,4.194828847,-0.313655704,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,zolpidem,DB00425
,37764,DB00555,10061428,81,6966,25,3461,0.03789565,1.609700753,1.014918809,2.636681057,0.101444868,DB0055510061428_,2.288239797,0.476048294,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,lamotrigine,DB00555
,37769,DB00451,10057362,131,47140,54,15365,0.146680085,0.790719215,0.571456692,1.10737576,0.2792914,DB0045110057362_,1.275499598,-0.23481235,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,37770,DB01109,10003658,49,4363,77,4193,0.007072503,0.611607127,0.417400462,0.888801774,0.026998874,DB0110910003658_,3.611960105,-0.491665152,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,heparin,DB01109
,37774,DB01109,10037377,103,4309,104,4166,0.77864717,0.95750789,0.719484773,1.274192109,0.879344398,DB0110910037377_,0.128578651,-0.043421317,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,heparin,DB01109
,37775,DB06605,10037377,319,13754,275,12758,0.38356222,1.07602754,0.911176092,1.271310476,0.553572159,DB0660510037377_,0.591363166,0.073276056,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,37780,DB00186,10016825,111,16790,26,9982,4.80255891136139e-06,2.538063975,1.642632637,4.057360667,5.70812846417066e-05,DB0018610016825_,9.77103426,0.931401576,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,lorazepam,DB00186
,37781,DB00335,10016825,49,8417,12,5453,0.001444866,2.645238667,1.385080119,5.468930227,0.007456228,DB0033510016825_,4.898705626,0.972761295,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,atenolol,DB00335
,37783,DB00335,10044565,92,8374,44,5421,0.111967918,1.353543765,0.933509477,1.988706813,0.229033208,DB0033510044565_,1.473888275,0.302726165,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,37785,DB00451,10013911,300,46971,98,15321,1,0.998510172,0.791760421,1.268411538,1,DB0045110013911_,0,-0.001490939,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,37786,DB00451,10024855,356,46915,118,15301,0.87248751,0.983956672,0.796187399,1.223223628,0.944186018,DB0045110024855_,0.057432079,-0.016173416,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,37788,DB00331,10017944,131,24815,69,20683,0.002134752,1.582399465,1.172670178,2.151300305,0.01026681,DB0033110017944_,4.57883891,0.458942344,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,37789,DB00331,10028735,138,24808,67,20685,0.000240677,1.717362394,1.272842338,2.336711782,0.001681158,DB0033110028735_,6.38827233,0.540789622,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,37790,DB00331,10040753,309,24637,94,20658,3.4730202078262e-20,2.756172333,2.179531184,3.512720226,3.64424495659527e-18,DB0033110040753_,40.15338247,1.013842881,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,metformin,DB00331
,37812,DB00635,10023439,45,33008,85,23709,8.8657911513999e-08,0.380271235,0.258754465,0.552267699,1.62169325271083e-06,DB0063510023439_,13.33203974,-0.966870503,NA,10023439,Kidney transplant rejection,10021428,Immune system disorders,Immun,prednisone,DB00635
,37813,DB00864,10023439,60,6809,80,8312,0.669775581,0.915531589,0.642938598,1.297834655,0.799629876,DB0086410023439_,0.223606314,-0.088250411,NA,10023439,Kidney transplant rejection,10021428,Immune system disorders,Immun,tacrolimus,DB00864
,37816,DB00864,10029354,85,6784,99,8293,0.76585003,1.049590031,0.774658318,1.419460146,0.870935515,DB0086410029354_,0.13818734,0.048399641,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,tacrolimus,DB00864
,37818,DB00087,10037660,102,1267,58,689,0.796782836,0.956378745,0.676418217,1.362473015,0.890017077,DB0008710037660_,0.116514628,-0.044601267,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,alemtuzumab,DB00087
,37819,DB01024,10037660,66,2145,61,2059,0.857373206,1.038588614,0.717991731,1.504352794,0.931607644,DB0102410037660_,0.070843536,0.03786269,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,mycophenolic acid,DB01024
,37830,DB00635,10028997,51,33002,40,23754,0.749906851,0.917714649,0.59454817,1.425428341,0.858375316,DB0063510028997_,0.152713844,-0.085868777,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,37831,DB00678,10028997,26,15573,33,10691,0.023325852,0.540913066,0.310460404,0.933091088,0.069636386,DB0067810028997_,2.664468056,-0.614496704,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,losartan,DB00678
,37832,DB00813,10028997,34,10538,25,10143,0.36158641,1.309002402,0.757709572,2.29050185,0.531426586,DB0081310028997_,0.632190216,0.269265322,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fentanyl,DB00813
,37834,DB00007,10034263,55,1892,6,4446,1.53797923158221e-22,21.53189273,9.261257248,61.28532329,2.0162485836478e-20,DB0000710034263_,45.35046321,3.069535219,female,10034263,Pelvic pain,10038604,Reproductive system and breast disorders,Repro,leuprolide,DB00007
,37850,DB00425,10013710,100,12595,80,7404,0.043800166,0.734847025,0.541375434,1.000145857,0.113187568,DB0042510013710_,2.17870894,-0.308092931,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,37851,DB00451,10013710,280,46991,153,15266,5.46387195573489e-07,0.594540898,0.486044729,0.729495136,8.40362050067241e-06,DB0045110013710_,11.68684793,-0.519965771,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,37852,DB00476,10013710,160,17097,94,6083,0.00018401,0.605620385,0.465701518,0.79126319,0.001344462,DB0047610013710_,6.611761445,-0.501501917,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,37853,DB00697,10013710,77,6019,17,1789,0.322721605,1.346197262,0.786239146,2.435383028,0.491069664,DB0069710013710_,0.711169279,0.297283775,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,37855,DB00843,10013710,70,2124,25,2148,3.45305099712166e-06,2.831084943,1.762436508,4.685199983,4.27122096279261e-05,DB0084310013710_,10.06102574,1.04066001,female,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,donepezil,DB00843
,37856,DB01098,10013710,86,8063,96,7113,0.117173627,0.790299635,0.582725918,1.070434529,0.236887567,DB0109810013710_,1.440169651,-0.235343121,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,37870,DB01076,10001760,286,25461,73,25510,8.23885059217887e-31,3.924943296,3.0240123,5.151154425,1.94222589968988e-28,DB0107610001760_,63.80854792,1.367351904,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,37873,DB00252,10025482,48,2184,19,1889,0.004145817,2.184625749,1.255264927,3.950335041,0.01758544,DB0025210025482_,4.04068397,0.781444532,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,phenytoin,DB00252
,37883,DB00590,10013700,42,734,55,1897,0.001792604,1.973121228,1.27593906,3.032237362,0.008890303,DB0059010013700_,4.722794129,0.679616669,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,doxazosin,DB00590
,37894,DB00564,10013573,104,2500,51,1412,0.44334924,1.151737814,0.810537442,1.654189606,0.611520204,DB0056410013573_,0.491807285,0.141271944,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,carbamazepine,DB00564
,37895,DB00230,10044565,426,19248,140,8511,0.002320739,1.345514634,1.107077676,1.643343689,0.010979794,DB0023010044565_,4.511698636,0.296776567,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,37896,DB00564,10044565,45,2559,28,1435,0.712326541,0.901256797,0.547410761,1.507286256,0.82893207,DB0056410044565_,0.18761707,-0.103965048,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,carbamazepine,DB00564
,37897,DB00563,10023230,271,46375,90,15258,0.951240915,0.990696112,0.777191867,1.2728332,0.989419202,DB0056310023230_,0.010637172,-0.009347439,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,37898,DB00563,10023469,141,46505,44,15304,0.798557852,1.054535214,0.746539966,1.515852016,0.891223384,DB0056310023469_,0.115160171,0.053100114,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,methotrexate,DB00563
,37903,DB00005,10066454,43,128039,11,42408,0.530078789,1.294722692,0.65651143,2.784316493,0.687176433,DB0000510066454_,0.375164204,0.258296535,NA,10066454,Weight bearing difficulty,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,37906,DB00264,10028997,46,29561,43,24849,0.670465831,0.899249793,0.580121516,1.396367745,0.800083838,DB0026410028997_,0.22303876,-0.106194427,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metoprolol,DB00264
,37907,DB00331,10028997,35,24911,26,20726,0.700926938,1.119974519,0.654944037,1.938183597,0.820314993,DB0033110028997_,0.198066875,0.113305934,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metformin,DB00331
,37908,DB00381,10028997,47,29313,49,22838,0.180467093,0.747319071,0.489833859,1.138975552,0.324424314,DB0038110028997_,1.125703008,-0.291263048,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,amlodipine,DB00381
,37910,DB00695,10028997,58,27991,29,20499,0.103153772,1.464672316,0.922174731,2.37366301,0.215729555,DB0069510028997_,1.533729717,0.381631543,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,furosemide,DB00695
,37912,DB01076,10028997,34,25713,55,25528,0.025763991,0.61374368,0.387863088,0.958551833,0.075174168,DB0107610028997_,2.587947619,-0.488177897,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,atorvastatin,DB01076
,37951,DB00736,10013709,481,10110,202,5351,0.006581599,1.26032417,1.063358547,1.497914813,0.025495149,DB0073610013709_,3.669267069,0.231368966,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,37952,DB00956,10013709,332,5482,174,3293,0.170486043,1.146167839,0.946156297,1.392090018,0.311488245,DB0095610013709_,1.166393678,0.136424064,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,37953,DB00451,10042674,417,46854,69,15350,2.28783827378611e-08,1.979788106,1.530467815,2.594842043,4.73137915235783e-07,DB0045110042674_,14.56387892,0.682989822,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,37954,DB01068,10042674,72,13691,22,6818,0.047765012,1.62975451,0.998106244,2.762350872,0.120898101,DB0106810042674_,2.112807233,0.488429396,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,37955,DB00736,10047899,169,10422,67,5486,0.053186692,1.327741526,0.992813867,1.792890759,0.131010422,DB0073610047899_,2.032478405,0.283479398,NA,10047899,Weight increased,10022891,Investigations,Inv,esomeprazole,DB00736
,37956,DB00956,10047899,122,5692,28,3439,8.83849232191364e-07,2.632251712,1.729856418,4.133102883,1.28637746778239e-05,DB0095610047899_,11.26109536,0.967839644,NA,10047899,Weight increased,10022891,Investigations,Inv,hydrocodone,DB00956
,37957,DB01068,10047899,291,13472,90,6750,4.57486409598925e-05,1.619991667,1.272296843,2.07943474,0.000409502,DB0106810047899_,7.800568434,0.482421005,NA,10047899,Weight increased,10022891,Investigations,Inv,clonazepam,DB01068
,37958,DB01069,10047899,112,6588,24,2371,0.018642813,1.679500132,1.070169326,2.737017289,0.058461743,DB0106910047899_,2.839382699,0.518496209,NA,10047899,Weight increased,10022891,Investigations,Inv,promethazine,DB01069
,37963,DB00996,10048948,37,38916,13,22412,0.142041528,1.639107054,0.851352608,3.361304401,0.272652102,DB0099610048948_,1.299558648,0.494151614,NA,10048948,Bedridden,10041244,Social circumstances,SocCi,gabapentin,DB00996
,37966,DB00335,10062355,53,8413,16,5449,0.00622512,2.145353983,1.206234068,4.025087839,0.024376504,DB0033510062355_,3.714135569,0.763304566,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,37967,DB00736,10062355,85,10506,39,5514,0.508336702,1.143868172,0.773037756,1.719360676,0.668934342,DB0073610062355_,0.402069367,0.134415652,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,37968,DB00956,10062355,39,5775,23,3444,1,1.01122431,0.587936207,1.776689889,1,DB0095610062355_,0,0.011161785,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,37969,DB01069,10062355,44,6656,13,2382,0.651390402,1.211229243,0.639345339,2.455616604,0.785818057,DB0106910062355_,0.241029994,0.191635747,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,37977,DB00227,10012735,121,2346,81,1722,0.559749472,1.096497127,0.814776474,1.481858296,0.712425667,DB0022710012735_,0.3390797,0.092120669,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lovastatin,DB00227
,37978,DB13961,10012735,646,8811,359,6055,0.001786709,1.236576795,1.080599508,1.416728398,0.008866084,DB1396110012735_,4.725522089,0.212346913,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,37979,DB00158,10060795,76,16739,25,8079,0.109998222,1.467220719,0.922212361,2.408877393,0.226050839,DB0015810060795_,1.486995352,0.383369944,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,folic acid,DB00158
,37982,DB00331,10060795,96,24850,73,20679,0.588508724,1.094369956,0.798297912,1.505554939,0.735420107,DB0033110060795_,0.307313368,0.090178815,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,metformin,DB00331
,37984,DB00999,10060795,93,21337,34,12205,0.026270582,1.564598513,1.045233205,2.392250961,0.076364085,DB0099910060795_,2.572242787,0.44762925,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,37985,DB01076,10060795,111,25636,124,25459,0.395445402,0.88898327,0.681407986,1.158583075,0.565106282,DB0107610060795_,0.570741456,-0.117676862,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,atorvastatin,DB01076
,37987,DB13961,10060795,62,9395,27,6387,0.064929127,1.561047032,0.977336206,2.554999715,0.152339739,DB1396110060795_,1.881642127,0.445356771,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,fish oil,DB13961
,37991,DB00451,10061599,89,47182,14,15405,0.008156416,2.075475435,1.174046358,3.951101155,0.030266307,DB0045110061599_,3.497720153,0.730190253,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,37995,DB06218,10011906,54,1640,73,1363,0.008254911,0.614889223,0.421075729,0.893243338,0.030539105,DB0621810011906_,3.488747273,-0.486313152,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,lacosamide,DB06218
,37997,DB00331,10022067,59,24887,61,20691,0.234324676,0.804146232,0.55226654,1.170144974,0.391210881,DB0033110022067_,0.938508528,-0.217974146,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,37998,DB00999,10022067,46,21384,17,12222,0.148792404,1.546524655,0.86941608,2.878804383,0.282313855,DB0099910022067_,1.264735865,0.436010255,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,38001,DB00331,10028391,105,24841,85,20667,0.884043382,1.027732175,0.76425702,1.385381546,0.951656815,DB0033110028391_,0.049550797,0.027354603,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,38002,DB00999,10028391,132,21298,57,12182,0.081135965,1.324571303,0.963022812,1.841886162,0.180313577,DB0099910028391_,1.713057851,0.281088862,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,38003,DB00563,10030041,59,46587,11,15337,0.095366013,1.765682641,0.918443503,3.728780678,0.203821251,DB0056310030041_,1.59051189,0.568537381,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,methotrexate,DB00563
,38013,DB06292,10013573,44,1313,38,1195,0.8233976,1.053829393,0.662058962,1.684240024,0.906247631,DB0629210013573_,0.098442687,0.05243057,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,dapagliflozin,DB06292
,38017,DB00331,10022998,64,24882,48,20704,0.635148057,1.109416225,0.750856428,1.648993377,0.773268489,DB0033110022998_,0.257128957,0.103833953,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,metformin,DB00331
,38020,DB00567,10053762,93,4426,48,2033,0.521986957,0.889975978,0.618999768,1.293889181,0.680711807,DB0056710053762_,0.384616254,-0.116560807,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cephalexin,DB00567
,38023,DB00451,10037844,1394,45877,337,15082,2.9153176410745e-07,1.359837727,1.204681778,1.538415231,4.77440026141079e-06,DB0045110037844_,12.25224219,0.307365374,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,38032,DB00175,10054112,64,8067,55,6051,0.458769572,0.872845733,0.598189691,1.277233314,0.626136258,DB0017510054112_,0.468187267,-0.135996448,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,pravastatin,DB00175
,38033,DB00186,10054112,145,16756,78,9930,0.531422937,1.101682464,0.829960809,1.471696793,0.688253647,DB0018610054112_,0.373597836,0.096838524,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,lorazepam,DB00186
,38034,DB00451,10054112,413,46858,138,15281,0.803884109,0.97597497,0.802270242,1.19323081,0.893912871,DB0045110054112_,0.112146968,-0.024318338,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,levothyroxine,DB00451
,38035,DB01118,10054112,36,3027,31,4678,0.0172456,1.794486596,1.076641246,3.006800181,0.055012208,DB0111810054112_,2.900200162,0.584718962,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,amiodarone,DB01118
,38039,DB00451,10056819,151,47120,35,15384,0.073060241,1.408521548,0.969296014,2.098254997,0.166613606,DB0045110056819_,1.792077883,0.342540607,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,38041,DB06285,10016173,344,8506,25,1081,0.005251323,1.748630513,1.15767418,2.753993478,0.021271128,DB0628510016173_,3.850404622,0.558832918,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,teriparatide,DB06285
,38044,DB00924,10013709,418,9744,176,4075,0.96335563,0.993239842,0.827584181,1.195957106,1,DB0092410013709_,0,-0.006783111,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,38047,DB11074,10013709,30,1230,24,844,0.578109922,0.857789562,0.480993372,1.544942666,0.726924,DB1107410013709_,0.318933346,-0.153396476,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dimethicone,DB11074
,38048,DB00531,10035226,124,7128,135,6381,0.131500112,0.822273517,0.63755817,1.059770853,0.257888566,DB0053110035226_,1.355227704,-0.195682194,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyclophosphamide,DB00531
,38050,DB00736,10035226,55,10536,41,5512,0.105374977,0.701787038,0.45925176,1.080122675,0.219171613,DB0073610035226_,1.517900235,-0.354125285,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,esomeprazole,DB00736
,38051,DB01042,10035226,56,934,98,1230,0.109217583,0.752615052,0.52598178,1.068251126,0.22485973,DB0104210035226_,1.492278493,-0.284201401,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,melphalan,DB01042
,38052,DB01137,10035226,61,7711,99,5494,4.10372350834907e-07,0.439031963,0.313135378,0.611327946,6.47457217388687e-06,DB0113710035226_,11.94762803,-0.823183059,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levofloxacin,DB01137
,38076,DB00480,10041549,22,67406,33,67629,0.176948912,0.668877606,0.371478204,1.182378846,0.319975704,DB0048010041549_,1.139510211,-0.402154186,NA,10041549,Spinal cord compression,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,38090,DB00188,10051055,129,7757,174,8654,0.116776359,0.827120707,0.652107515,1.046919015,0.236267297,DB0018810051055_,1.442791501,-0.189804637,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,bortezomib,DB00188
,38091,DB00787,10051055,209,16791,294,16954,0.000268083,0.717795213,0.597460098,0.861145278,0.001841037,DB0078710051055_,6.297426247,-0.33157097,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,acyclovir,DB00787
,38092,DB00924,10051055,65,10097,50,4201,0.001387042,0.540937856,0.367672736,0.799897856,0.007208068,DB0092410051055_,4.932554348,-0.614450875,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,cyclobenzaprine,DB00924
,38094,DB01137,10051055,52,7720,51,5542,0.132240621,0.731979405,0.486939941,1.100739577,0.258983326,DB0113710051055_,1.350991596,-0.312002901,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,levofloxacin,DB01137
,38099,DB06292,10012174,34,1323,29,1204,0.898520196,1.066956358,0.626657168,1.827253028,0.956423691,DB0629210012174_,0.044554273,0.06481007,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,dapagliflozin,DB06292
,38101,DB00983,10008469,83,3418,33,1707,0.318723543,1.256005914,0.825935419,1.949965672,0.486775418,DB0098310008469_,0.719952416,0.227936777,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,formoterol,DB00983
,38104,DB00005,10035155,48,128034,20,42399,0.400186214,0.794767833,0.462779598,1.413892856,0.570052547,DB0000510035155_,0.562026734,-0.229705241,NA,10035155,Plantar fasciitis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,38108,DB00476,10042772,103,17154,67,6110,0.000217395,0.547602741,0.398087746,0.757450888,0.001546058,DB0047610042772_,6.472046671,-0.60220518,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,38109,DB00497,10042772,84,19183,91,16284,0.110723109,0.783587637,0.57505239,1.06673769,0.227167538,DB0049710042772_,1.482067483,-0.24387237,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,38110,DB00999,10042772,155,21275,134,12105,0.000453625,0.658183968,0.518340329,0.836611986,0.00284809,DB0099910042772_,5.861106655,-0.4182708,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,38111,DB01076,10042772,195,25552,218,25365,0.235947409,0.887951653,0.727582915,1.08302807,0.393145969,DB0107610042772_,0.933574314,-0.118837982,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,38112,DB01156,10042772,52,13570,30,6298,0.343235688,0.80449267,0.503194279,1.307516505,0.512523437,DB0115610042772_,0.668408838,-0.217543423,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,38116,DB01104,10015150,131,15332,37,7249,0.004698511,1.673940196,1.152983453,2.483624839,0.019456449,DB0110410015150_,3.939576694,0.515180246,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,sertraline,DB01104
,38119,DB01104,10016334,53,15410,10,7276,0.006287044,2.502367468,1.258956313,5.519467605,0.024586022,DB0110410016334_,3.705577197,0.917237271,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,38120,DB00182,10033371,195,4999,52,2800,6.93002849079944e-07,2.100246083,1.533687062,2.920128584,1.03644835778471e-05,DB0018210033371_,11.47712564,0.74205452,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,38123,DB08895,10046571,734,27380,35,6611,5.6708859653524e-33,5.063512335,3.603168857,7.334856645,1.53669317112668e-30,DB0889510046571_,68.64791997,1.62206038,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,38125,DB00787,10015916,36,16964,23,17225,0.090325117,1.589267939,0.915940526,2.810407513,0.195758653,DB0078710015916_,1.63087274,0.463273494,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,acyclovir,DB00787
,38127,DB01076,10015916,55,25692,32,25551,0.017781806,1.709289529,1.085607162,2.732581518,0.056356758,DB0107610015916_,2.876053112,0.536077804,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,atorvastatin,DB01076
,38132,DB00338,10000059,481,33193,255,22017,0.003950922,1.251156983,1.071606416,1.46344944,0.016905991,DB0033810000059_,4.080087197,0.22406871,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,38133,DB01175,10000059,120,10604,49,4843,0.559734888,1.118472393,0.794424983,1.595837263,0.712424354,DB0117510000059_,0.339081543,0.111963819,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,38134,DB01592,10000059,102,6174,27,3040,0.003311863,1.860020466,1.203978252,2.964775145,0.01465527,DB0159210000059_,4.222955258,0.620587491,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,38135,DB00338,10000060,310,33364,152,22120,0.002236152,1.352142982,1.109211109,1.654086083,0.010652773,DB0033810000060_,4.541935064,0.301690728,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,38136,DB01175,10000060,79,10645,24,4868,0.08785312,1.505255682,0.941620028,2.489341515,0.191604652,DB0117510000060_,1.652321134,0.408962772,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,38137,DB01592,10000060,60,6216,25,3042,0.562540735,1.174483133,0.723669211,1.959020611,0.714753401,DB0159210000060_,0.335817689,0.160828164,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,38138,DB00451,10003119,89,47182,37,15382,0.214702402,0.784199541,0.528581944,1.184457773,0.367076292,DB0045110003119_,1.002185573,-0.243091774,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,38139,DB00451,10020751,515,46756,91,15328,8.27528885880364e-09,1.855183718,1.480841314,2.346598341,1.89556398826713e-07,DB0045110020751_,15.47857924,0.617983731,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,levothyroxine,DB00451
,38140,DB00398,10000087,28,699,67,1471,0.65367606,0.879520807,0.53949176,1.400576313,0.787749099,DB0039810000087_,0.238575642,-0.128378057,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,sorafenib,DB00398
,38146,DB00060,10001949,82,9426,20,2445,0.902298672,1.063523462,0.644605173,1.834871365,0.957195726,DB0006010001949_,0.043747388,0.061587417,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,38147,DB00316,10001949,246,65228,104,36849,0.014043657,1.336263799,1.057910507,1.697814564,0.046708532,DB0031610001949_,3.063828427,0.28987751,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,38151,DB00316,10009866,66,65408,42,36911,0.548566346,0.886792121,0.593191049,1.33883307,0.702991878,DB0031610009866_,0.352409941,-0.120144686,NA,10009866,Cold sweat,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,38153,DB00316,10020096,66,65408,30,36923,0.340866007,1.241945111,0.794997599,1.981513837,0.510109204,DB0031610020096_,0.673130451,0.216678788,NA,10020096,Hip arthroplasty,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,38154,DB00060,10021097,47,9461,10,2455,0.742244994,1.219564317,0.607053348,2.710934426,0.852277468,DB0006010021097_,0.159843138,0.198493678,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,interferon beta-1a,DB00060
,38156,DB00316,10022004,408,65066,153,36800,9.91832969367365e-06,1.508206067,1.248907287,1.829119505,0.00010784,DB0031610022004_,9.134861543,0.41092091,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,38158,DB00316,10040943,109,65365,55,36898,0.51626935,1.118734254,0.801569077,1.577012821,0.675921593,DB0031610040943_,0.391678196,0.112197916,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,38159,DB00316,10048334,207,65267,86,36867,0.017373974,1.359611279,1.052020047,1.769958165,0.055345109,DB0031610048334_,2.894166994,0.307198834,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,38160,DB00316,10050296,155,65319,41,36912,4.81348630439408e-06,2.136350228,1.505298452,3.093334736,5.71853050897168e-05,DB0031610050296_,9.769213597,0.759098872,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,38162,DB00316,10052428,99,65375,49,36904,0.493595272,1.14053369,0.801792875,1.641112871,0.65628771,DB0031610052428_,0.421156004,0.131496302,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,38167,DB00316,10061521,33,65441,23,36930,0.486756286,0.809697795,0.461204252,1.44439155,0.650633831,DB0031610061521_,0.429808266,-0.211094193,NA,10061521,Intervertebral disc disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,38170,DB00316,10069868,217,65257,38,36915,5.84529051187568e-14,3.230329142,2.279808337,4.689758008,3.09141772846383e-12,DB0031610069868_,26.50239132,1.172584034,female,10069868,Device issue,10077536,Product issues,Prod,acetaminophen,DB00316
,38176,DB00264,10004146,31,29576,23,24869,0.683772994,1.133302479,0.639561875,2.035953326,0.808846477,DB0026410004146_,0.212146149,0.125135918,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metoprolol,DB00264
,38178,DB00480,10004146,69,67359,160,67502,1.64737907243334e-09,0.432142077,0.320986488,0.576742637,4.38494773862383e-08,DB0048010004146_,16.94250304,-0.839000863,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,38182,DB01234,10004146,29,31596,71,32817,5.32669002790018e-05,0.424268865,0.265411731,0.662224503,0.000466085,DB0123410004146_,7.671141727,-0.857387909,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,38194,DB00264,10040808,27,29580,40,24852,0.026515597,0.567122728,0.33455972,0.947559338,0.076893475,DB0026410040808_,2.56533426,-0.567179546,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metoprolol,DB00264
,38196,DB00480,10040808,73,67355,177,67485,3.74425314797347e-11,0.413204209,0.310133402,0.545811348,1.30961668655333e-09,DB0048010040808_,20.45353135,-0.883813355,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,38200,DB01234,10040808,18,31607,55,32833,2.95653029326542e-05,0.339943275,0.187825536,0.588077348,0.000280146,DB0123410040808_,8.18020097,-1.078976514,male,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,38205,DB00480,10041834,73,67355,180,67482,1.28990965329447e-11,0.406299766,0.305136698,0.536293451,4.82637369919503e-10,DB0048010041834_,21.45175553,-0.900664053,NA,10041834,Squamous cell carcinoma of skin,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,38209,DB01234,10041834,42,31583,92,32796,4.10386482062501e-05,0.474062574,0.320858749,0.690271884,0.000372866,DB0123410041834_,7.894291888,-0.746415953,NA,10041834,Squamous cell carcinoma of skin,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,38212,DB01268,10015090,45,2098,72,3058,0.703571364,0.910984219,0.61068315,1.346451951,0.822205647,DB0126810015090_,0.195764736,-0.093229705,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sunitinib,DB01268
,38213,DB01268,10037087,61,2082,71,3059,0.208883144,1.262252617,0.877347215,1.811589143,0.359949974,DB0126810037087_,1.021790218,0.232897916,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,sunitinib,DB01268
,38216,DB00203,10040829,41,13837,27,8911,1,0.977914149,0.586782542,1.654423605,1,DB0020310040829_,0,-0.022333395,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,sildenafil,DB00203
,38222,DB00207,10013710,55,9025,88,5367,5.62493024910807e-09,0.371701224,0.259977373,0.527477578,1.33619312186924e-07,DB0020710013710_,15.82827103,-0.989664909,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,38224,DB00564,10013710,46,2558,29,1434,0.628600566,0.88924784,0.544127759,1.474875022,0.76784714,DB0056410013710_,0.264164602,-0.117379297,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,carbamazepine,DB00564
,38225,DB01409,10013710,45,5986,39,3927,0.218545511,0.756992236,0.480989208,1.195937681,0.371730597,DB0140910013710_,0.989585889,-0.278402282,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,38226,DB00231,10002855,85,3211,25,2114,0.000238028,2.238123613,1.413099237,3.662487849,0.00166606,DB0023110002855_,6.397293575,0.805637842,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,temazepam,DB00231
,38227,DB00586,10002855,141,6968,27,2778,0.000259812,2.081864727,1.368210531,3.277627715,0.001793794,DB0058610002855_,6.323422359,0.733263995,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,diclofenac,DB00586
,38229,DB00231,10003239,81,3215,35,2104,0.043558317,1.51443242,1.002684973,2.329588615,0.112739931,DB0023110003239_,2.182671609,0.415040729,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,temazepam,DB00231
,38230,DB00295,10003239,190,14473,104,9498,0.149845483,1.198893332,0.937670687,1.53994105,0.283705866,DB0029510003239_,1.259817262,0.181398908,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,38231,DB00316,10003239,1632,63842,647,36306,4.23868593108389e-15,1.434452742,1.307595041,1.575072845,2.63078771425124e-13,DB0031610003239_,28.9663229,0.360783412,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,38232,DB00497,10003239,398,18869,233,16142,4.14168918860871e-06,1.461268237,1.238222925,1.727669417,5.00519960917508e-05,DB0049710003239_,9.902448171,0.379304714,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,38239,DB00497,10010214,30,19237,21,16354,0.574460857,1.214467588,0.672268526,2.232761047,0.724237911,DB0049710010214_,0.322635335,0.194305782,NA,10010214,Compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,38243,DB01373,10010214,38,22682,16,7365,0.427867257,0.771185897,0.419573242,1.482350045,0.596364589,DB0137310010214_,0.516903073,-0.259825823,NA,10010214,Compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,38246,DB00316,10013754,280,65194,148,36805,0.545163065,1.068064928,0.871694031,1.31300236,0.699978563,DB0031610013754_,0.356705568,0.065848532,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,38247,DB00333,10013754,70,3001,62,3090,0.428681709,1.162486366,0.810843851,1.670000357,0.597212069,DB0033310013754_,0.515483005,0.150561131,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,methadone,DB00333
,38248,DB00425,10013754,77,12618,44,7440,0.92492455,1.031859323,0.702569905,1.532138673,0.967723825,DB0042510013754_,0.032808537,0.031362343,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,38253,DB00231,10013968,142,3154,79,2060,0.29170868,1.173932253,0.880182752,1.575066248,0.457191739,DB0023110013968_,0.782652416,0.160359014,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,temazepam,DB00231
,38257,DB00295,10014387,26,14637,38,9564,0.001878708,0.447082303,0.2604344,0.756373736,0.009248634,DB0029510014387_,4.683279439,-0.805012579,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,morphine,DB00295
,38258,DB00316,10014387,139,65335,79,36874,1,0.993028095,0.747844725,1.326439951,1,DB0031610014387_,0,-0.006996322,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,acetaminophen,DB00316
,38259,DB00333,10014387,30,3041,109,3043,1.22371425435148e-11,0.275430879,0.176896246,0.417362792,4.61151672768868e-10,DB0033310014387_,21.49729412,-1.289418576,male,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,methadone,DB00333
,38260,DB00425,10014387,39,12656,12,7472,0.057981668,1.91871544,0.983494862,4.028134923,0.139667167,DB0042510014387_,1.968493062,0.651655921,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,zolpidem,DB00425
,38261,DB00497,10014387,41,19226,42,16333,0.440528374,0.829306568,0.525688192,1.307468179,0.608907439,DB0049710014387_,0.496089012,-0.187165388,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,oxycodone,DB00497
,38266,DB00231,10017577,51,3245,29,2110,0.645034598,1.143517298,0.70854249,1.877516601,0.780833021,DB0023110017577_,0.247393954,0.134108862,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,38268,DB00425,10017577,174,12521,90,7394,0.336178701,1.141705385,0.878621157,1.49194942,0.505257999,DB0042510017577_,0.682686091,0.132523096,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,38269,DB00586,10017577,117,6992,34,2771,0.121829529,1.36368939,0.921250362,2.066737007,0.244011823,DB0058610017577_,1.410538599,0.310193814,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,38272,DB00295,10020100,31,14632,25,9577,0.494309275,0.811624696,0.463459577,1.434684815,0.656821742,DB0029510020100_,0.420342619,-0.208717243,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,38273,DB00316,10020100,205,65269,116,36837,1,0.997408582,0.790162955,1.264063086,1,DB0031610020100_,0,-0.002594782,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,38275,DB00425,10020100,39,12656,23,7461,1,0.999625558,0.581809462,1.754575504,1,DB0042510020100_,0,-0.000374512,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,38276,DB00497,10020100,57,19210,43,16332,0.615692936,1.126964548,0.744866684,1.716319018,0.757016036,DB0049710020100_,0.278370842,0.119527778,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,38278,DB00820,10020100,54,11861,14,5802,0.037505667,1.88672389,1.032509879,3.681247652,0.100600689,DB0082010020100_,2.296596177,0.634841933,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,tadalafil,DB00820
,38280,DB01373,10020100,141,22579,35,7346,0.160421864,1.31065783,0.898815834,1.958140382,0.298062395,DB0137310020100_,1.210452437,0.270529171,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,38281,DB00231,10021097,69,3227,38,2101,0.426129244,1.182136048,0.781209305,1.812911733,0.594791024,DB0023110021097_,0.519545155,0.167323012,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,temazepam,DB00231
,38282,DB00333,10021097,35,3036,62,3090,0.010174321,0.574610305,0.367244065,0.886393526,0.036058384,DB0033310021097_,3.322615877,-0.554063198,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,methadone,DB00333
,38283,DB00425,10021097,231,12464,111,7373,0.079981421,1.231000554,0.975607819,1.561059122,0.178388769,DB0042510021097_,1.723790016,0.207827297,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,zolpidem,DB00425
,38284,DB00586,10021097,62,7047,41,2764,0.011257326,0.59315316,0.392377351,0.905115965,0.039126321,DB0058610021097_,3.24095988,-0.522302633,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,diclofenac,DB00586
,38286,DB00231,10022437,103,3193,63,2076,0.747222452,1.062977086,0.765444379,1.485903028,0.856161658,DB0023110022437_,0.155296067,0.061073543,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,temazepam,DB00231
,38287,DB00295,10022437,167,14496,107,9495,0.901168552,1.022302898,0.796040439,1.317512176,0.956927891,DB0029510022437_,0.044027239,0.022057825,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,morphine,DB00295
,38288,DB00333,10022437,30,3041,42,3110,0.194652397,0.730531944,0.440221099,1.198781292,0.342557462,DB0033310022437_,1.071315863,-0.313982319,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,methadone,DB00333
,38289,DB00425,10022437,410,12285,233,7251,0.678276767,1.038606428,0.879802101,1.228387777,0.805062194,DB0042510022437_,0.216835745,0.037879841,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,38291,DB01373,10022437,404,22316,104,7277,0.032907468,1.266710173,1.016977847,1.58952616,0.091083324,DB0137310022437_,2.39598054,0.236423124,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,calcium,DB01373
,38292,DB00231,10025482,136,3160,40,2099,2.97418858119373e-06,2.258100815,1.569247573,3.313090025,3.75939152953485e-05,DB0023110025482_,10.18866835,0.814524113,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,38293,DB00295,10025482,302,14361,147,9455,0.002926752,1.352573876,1.104986143,1.661641264,0.013242047,DB0029510025482_,4.324358117,0.302009352,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,38294,DB00333,10025482,61,3010,40,3112,0.027191247,1.57655265,1.037484994,2.419235745,0.078433134,DB0033310025482_,2.545508812,0.455240596,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,methadone,DB00333
,38295,DB00425,10025482,385,12310,143,7341,9.55760796629961e-07,1.605506285,1.318696593,1.963554926,1.3758035344698e-05,DB0042510025482_,11.19388752,0.473439149,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,38296,DB00497,10025482,507,18760,302,16073,6.64529738085197e-07,1.438333714,1.242877209,1.666802935,9.96984256025651e-06,DB0049710025482_,11.51594577,0.3634853,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,38298,DB01373,10025482,629,22091,142,7239,4.54346396001353e-05,1.451473803,1.205558014,1.757451221,0.000407107,DB0137310025482_,7.806433572,0.372579456,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,38299,DB00203,10028372,99,13779,45,8893,0.05918677,1.419863945,0.987488824,2.069432054,0.141965073,DB0020310028372_,1.952174215,0.350561054,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,38300,DB00231,10028372,36,3260,19,2120,0.491444532,1.232093456,0.686141835,2.280441408,0.654570398,DB0023110028372_,0.42377614,0.208714719,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,temazepam,DB00231
,38301,DB00295,10028372,77,14586,73,9529,0.02377278,0.689123074,0.493195689,0.963580781,0.070722372,DB0029510028372_,2.648993321,-0.372335396,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,38303,DB00425,10028372,111,12584,65,7419,1,1.006783696,0.733659007,1.391221109,1,DB0042510028372_,0,0.00676079,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,38304,DB00497,10028372,114,19153,109,16266,0.381747115,0.888227431,0.676461324,1.166725278,0.551876742,DB0049710028372_,0.594430551,-0.118527453,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,38305,DB00586,10028372,65,7044,17,2788,0.140217342,1.51334224,0.87472577,2.759001995,0.270146804,DB0058610028372_,1.308789749,0.414320609,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,38306,DB00820,10028372,104,11811,33,5783,0.028470314,1.543036145,1.032702907,2.360488336,0.081319448,DB0082010028372_,2.509370083,0.433751998,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,38308,DB01373,10028372,218,22502,53,7328,0.055747112,1.339478261,0.986865777,1.846598494,0.13561433,DB0137310028372_,1.997940228,0.292280181,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,38310,DB00295,10028596,47,14616,52,9550,0.009810125,0.590599712,0.389097912,0.894341398,0.035035208,DB0029510028596_,3.351401767,-0.526616797,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,morphine,DB00295
,38311,DB00425,10028596,53,12642,68,7416,2.60981899008695e-05,0.457227591,0.312727169,0.665385532,0.000250545,DB0042510028596_,8.291873891,-0.782574,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,zolpidem,DB00425
,38312,DB00497,10028596,78,19189,101,16274,0.005310306,0.654975644,0.480693444,0.889587485,0.021464155,DB0049710028596_,3.84137096,-0.423157229,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,oxycodone,DB00497
,38315,DB01373,10028596,84,22636,60,7321,5.99464073017057e-06,0.45279907,0.320902001,0.642303913,6.92459378565298e-05,DB0137310028596_,9.577846074,-0.792306806,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,calcium,DB01373
,38319,DB00316,10041569,111,65363,67,36886,0.696233864,0.934928535,0.684059751,1.286116897,0.817238577,DB0031610041569_,0.20182421,-0.067285186,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,38322,DB00497,10041569,59,19208,56,16319,0.574717103,0.895111394,0.609954856,1.314922876,0.724373112,DB0049710041569_,0.322448671,-0.110807106,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,38326,DB01373,10041569,78,22642,16,7365,0.093725854,1.585673517,0.917193504,2.912011664,0.201306101,DB0137310041569_,1.60292864,0.461009249,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,38327,DB00203,10043882,33,13845,26,8912,0.504600894,0.817016157,0.473547117,1.423478394,0.66555134,DB0020310043882_,0.407139499,-0.202096409,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,sildenafil,DB00203
,38330,DB00497,10043882,35,19232,38,16337,0.34707561,0.782415497,0.479680832,1.272845277,0.516511389,DB0049710043882_,0.660657941,-0.245369353,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,oxycodone,DB00497
,38332,DB00820,10043882,59,11856,26,5790,0.728958548,1.108192091,0.686787836,1.833897523,0.842005424,DB0082010043882_,0.171968823,0.10272994,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,tadalafil,DB00820
,38334,DB01373,10043882,63,22657,15,7366,0.355659767,1.365427743,0.767959625,2.583943636,0.525383011,DB0137310043882_,0.643627738,0.311467744,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,calcium,DB01373
,38335,DB00203,10047571,104,13774,75,8863,0.489160277,0.892269282,0.655858597,1.21881315,0.652567206,DB0020310047571_,0.426841148,-0.113987306,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,sildenafil,DB00203
,38337,DB00295,10047571,39,14624,24,9578,0.89757941,1.064300763,0.623697437,1.851367845,0.956338178,DB0029510047571_,0.044643686,0.062318023,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,morphine,DB00295
,38339,DB00425,10047571,85,12610,32,7452,0.034231431,1.569702801,1.033000579,2.439019942,0.093873048,DB0042510047571_,2.365811966,0.450886303,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,zolpidem,DB00425
,38340,DB00497,10047571,90,19177,48,16327,0.009997086,1.596321058,1.111696923,2.317263953,0.035558368,DB0049710047571_,3.336579768,0.467701643,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,oxycodone,DB00497
,38341,DB00586,10047571,50,7059,21,2784,0.79246178,0.939026116,0.552596776,1.649200507,0.887531177,DB0058610047571_,0.119311629,-0.062911988,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,diclofenac,DB00586
,38342,DB00820,10047571,76,11839,27,5789,0.171469359,1.376377572,0.875663281,2.224253806,0.312810026,DB0082010047571_,1.162159219,0.3194551,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,tadalafil,DB00820
,38344,DB00231,10047895,73,3223,37,2102,0.237218518,1.286689659,0.851373599,1.973984477,0.394588581,DB0023110047895_,0.929911624,0.252072764,NA,10047895,Weight decreased,10022891,Investigations,Inv,temazepam,DB00231
,38345,DB00333,10047895,40,3031,36,3116,0.566710726,1.14224533,0.707635967,1.84977869,0.718034823,DB0033310047895_,0.331237211,0.132995913,NA,10047895,Weight decreased,10022891,Investigations,Inv,methadone,DB00333
,38346,DB00586,10047895,136,6973,52,2753,0.934858043,1.032597959,0.742416602,1.454728638,0.975205622,DB0058610047895_,0.025106936,0.032077917,NA,10047895,Weight decreased,10022891,Investigations,Inv,diclofenac,DB00586
,38347,DB00820,10047895,437,11478,154,5662,0.000355981,1.399769628,1.158928168,1.697860419,0.002326443,DB0082010047895_,6.063414653,0.336307671,NA,10047895,Weight decreased,10022891,Investigations,Inv,tadalafil,DB00820
,38349,DB00203,10047924,119,13759,35,8903,2.0028407903948e-05,2.19995245,1.49640667,3.308959761,0.000199942,DB0020310047924_,8.517484343,0.788435747,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,38351,DB00295,10047924,27,14636,30,9572,0.056648499,0.588635821,0.336443487,1.025156845,0.137206119,DB0029510047924_,1.986270965,-0.529947587,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,38353,DB00425,10047924,48,12647,22,7462,0.385883991,1.287309502,0.7614886,2.241145496,0.556037646,DB0042510047924_,0.586919279,0.252554383,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,38354,DB00497,10047924,34,19233,38,16337,0.286720544,0.760022719,0.463880637,1.240661711,0.451487165,DB0049710047924_,0.795208334,-0.274406953,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,38357,DB01373,10047924,67,22653,12,7369,0.065557784,1.816140143,0.973610064,3.691381596,0.15341759,DB0137310047924_,1.874591732,0.596713448,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,38369,DB00203,10048908,66,13812,30,8908,0.116898523,1.418860821,0.907605648,2.265389182,0.236478353,DB0020310048908_,1.441898604,0.349854311,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,sildenafil,DB00203
,38372,DB00316,10048908,143,65331,49,36904,0.002001902,1.648511248,1.183699142,2.330060203,0.009730926,DB0031610048908_,4.632446198,0.499872607,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,acetaminophen,DB00316
,38377,DB00820,10048908,78,11837,7,5809,1.50816339746143e-07,5.468443014,2.529783034,14.060744,2.63752993361768e-06,DB0082010048908_,12.84566771,1.698993935,female,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,tadalafil,DB00820
,38379,DB01373,10048908,83,22637,30,7351,0.585763833,0.89842081,0.584779226,1.41460632,0.733111244,DB0137310048908_,0.310457823,-0.107116713,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,calcium,DB01373
,38383,DB00316,10057040,60,65414,34,36919,1,0.995981764,0.64328407,1.565095902,1,DB0031610057040_,0,-0.004026331,NA,10057040,Temperature intolerance,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,38395,DB00451,10000880,44,47227,21,15398,0.150903408,0.683141091,0.397497496,1.209961735,0.285176921,DB0045110000880_,1.254645518,-0.381053866,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levothyroxine,DB00451
,38399,DB00338,10016288,149,33525,128,22144,0.031228879,0.768903395,0.602651584,0.982133992,0.087417582,DB0033810016288_,2.437058849,-0.262789941,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,omeprazole,DB00338
,38400,DB00451,10016288,133,47138,67,15352,0.004996523,0.646508457,0.478184316,0.881164306,0.020457438,DB0045110016288_,3.88940877,-0.436169,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,levothyroxine,DB00451
,38401,DB01076,10016288,53,25694,88,25495,0.003056952,0.597617829,0.416597249,0.850158145,0.013735382,DB0107610016288_,4.287780161,-0.514803812,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,atorvastatin,DB01076
,38404,DB00338,10064687,41,33633,24,22248,0.704414527,1.130078262,0.666592016,1.955819466,0.822821279,DB0033810064687_,0.195016259,0.122286889,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,38405,DB00451,10064687,52,47219,19,15400,0.679523705,0.892581309,0.51872254,1.599201415,0.8061236,DB0045110064687_,0.215518199,-0.113637667,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,38409,DB00646,10002855,60,3393,22,1978,0.065153609,1.589777799,0.957525103,2.730693134,0.152709671,DB0064610002855_,1.879216734,0.463594257,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,nystatin,DB00646
,38410,DB00697,10002855,161,5935,29,1777,0.011000771,1.662095367,1.109613769,2.570396521,0.038408709,DB0069710002855_,3.259471039,0.508079076,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,tizanidine,DB00697
,38412,DB00697,10003549,210,5886,49,1757,0.13258813,1.27925936,0.928759928,1.791951376,0.259412632,DB0069710003549_,1.34933531,0.246281286,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,38414,DB00697,10010305,83,6013,15,1791,0.089108467,1.647994149,0.940972493,3.084169706,0.193819857,DB0069710010305_,1.640826124,0.499558881,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,tizanidine,DB00697
,38416,DB00497,10012378,262,19005,184,16191,0.049867089,1.213072011,0.999612776,1.474548422,0.124780981,DB0049710012378_,2.081195232,0.193155994,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,38417,DB00829,10012378,200,7852,91,4363,0.121777608,1.221154709,0.945681824,1.586962044,0.243945009,DB0082910012378_,1.410812452,0.199796894,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,38418,DB01075,10012378,207,19741,88,11009,0.032760327,1.311790845,1.016231814,1.705086799,0.090747729,DB0107510012378_,2.399671832,0.271393261,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,38420,DB00295,10013709,439,14224,310,9292,0.305648249,0.925107153,0.796152882,1.075962028,0.472419394,DB0029510013709_,0.749888141,-0.077845707,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,38421,DB00697,10016256,436,5660,92,1714,0.001834732,1.43503254,1.135704346,1.829070637,0.009063319,DB0069710016256_,4.703519843,0.361187525,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,38422,DB00295,10016322,143,14520,91,9511,0.893168935,1.029329779,0.784864422,1.355712878,0.955474763,DB0029510016322_,0.045546928,0.028907891,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,38423,DB00451,10016322,935,46336,193,15226,1.13403275656879e-09,1.591850755,1.3604329,1.870528754,3.11636706810356e-08,DB0045110016322_,17.28401282,0.464897336,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,38424,DB00646,10016322,42,3411,8,1992,0.001758095,3.065443523,1.418035674,7.573843065,0.008744732,DB0064610016322_,4.739303845,1.120192265,female,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,38425,DB00829,10016322,155,7897,51,4403,0.00092302,1.694458899,1.224641844,2.378356108,0.005157649,DB0082910016322_,5.267274424,0.527363456,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,38434,DB00295,10022998,24,14639,33,9569,0.006235993,0.475400722,0.268688171,0.829717643,0.024406354,DB0029510022998_,3.712911753,-0.743597206,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,morphine,DB00295
,38435,DB00497,10022998,52,19215,65,16310,0.040745627,0.679067007,0.46200458,0.993777861,0.107126661,DB0049710022998_,2.233743395,-0.387035472,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,38438,DB00829,10022998,46,8006,29,4425,0.628801462,0.876727188,0.538274552,1.449438204,0.767981646,DB0082910022998_,0.263989444,-0.131559409,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,38440,DB00646,10025482,127,3326,49,1951,0.013603277,1.520236257,1.079615205,2.169942193,0.045491365,DB0064610025482_,3.090232758,0.418865755,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,38441,DB00697,10025482,245,5851,34,1772,5.80950781813312e-06,2.182289718,1.513342617,3.235979348,6.73590264665324e-05,DB0069710025482_,9.605473641,0.780374655,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,38442,DB00829,10025482,234,7818,71,4383,3.70458351681205e-06,1.847624094,1.407112433,2.451298469,4.54068443643761e-05,DB0082910025482_,9.999847707,0.61390054,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,38443,DB01075,10025482,487,19461,206,10891,0.000753075,1.323002182,1.119854099,1.567461832,0.004347114,DB0107510025482_,5.4382432,0.279903534,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,38445,DB00295,10033557,70,14593,24,9578,0.005720158,1.914278689,1.188015708,3.185383169,0.02278963,DB0029510033557_,3.78144967,0.649340888,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,morphine,DB00295
,38446,DB00497,10033557,90,19177,30,16345,3.24955410819947e-06,2.556816575,1.673708511,4.00728074,4.05962593792886e-05,DB0049710033557_,10.11183463,0.938762959,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,oxycodone,DB00497
,38448,DB00697,10033557,47,6049,13,1793,1,1.071624816,0.568851042,2.164114296,1,DB0069710033557_,0,0.069176017,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,tizanidine,DB00697
,38449,DB00829,10033557,51,8001,11,4443,0.003103843,2.574426552,1.323350894,5.483636635,0.013912774,DB0082910033557_,4.274947866,0.945626811,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,diazepam,DB00829
,38450,DB01075,10033557,138,19810,25,11072,8.91849356838004e-09,3.085082972,2.002984046,4.934896775,2.02875468147875e-07,DB0107510033557_,15.4106735,1.126578552,female,10033557,Palpitations,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,38453,DB00451,10033664,85,47186,6,15413,1.32116135863139e-05,4.627455445,2.039645624,12.9657905,0.000138657,DB0045110033664_,8.883504978,1.532007137,female,10033664,Panic attack,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,38454,DB00497,10033664,33,19234,24,16351,0.596689625,1.168894487,0.669910176,2.067787219,0.742050851,DB0049710033664_,0.298337506,0.156058419,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,38468,DB00295,10062355,75,14588,58,9544,0.37400288,0.846005939,0.591915114,1.214447874,0.543821746,DB0029510062355_,0.609133758,-0.167228899,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,38471,DB00829,10062355,63,7989,33,4421,0.831432854,1.056463439,0.681562983,1.665025183,0.911903051,DB0082910062355_,0.092221599,0.054926951,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,38472,DB01075,10062355,115,19833,64,11033,1,0.999592701,0.729399468,1.380344493,1,DB0107510062355_,0,-0.000407382,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,38474,DB08816,10011906,30,1121,79,1823,0.026700929,0.617646182,0.388872223,0.958389888,0.07735412,DB0881610011906_,2.559361438,-0.481839506,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ticagrelor,DB08816
,38477,DB00108,10028372,147,10047,70,3225,0.008453273,0.674103673,0.502276603,0.911996573,0.03112515,DB0010810028372_,3.469739099,-0.394371363,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,natalizumab,DB00108
,38480,DB00316,10016825,383,65091,167,36786,0.005010589,1.296125879,1.077436148,1.564676953,0.020495384,DB0031610016825_,3.887555606,0.259379722,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,38482,DB00904,10016825,161,22908,71,14385,0.014663685,1.42392192,1.069646798,1.911720831,0.048424519,DB0090410016825_,3.027749009,0.35341498,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,ondansetron,DB00904
,38484,DB01068,10016825,81,13682,17,6823,0.000539106,2.375999842,1.39496427,4.280752531,0.003283604,DB0106810016825_,5.71881362,0.865418335,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,clonazepam,DB01068
,38486,DB06637,10016825,128,6034,45,1974,0.656925381,0.930550625,0.654998491,1.343022169,0.790246614,DB0663710016825_,0.235410213,-0.071978798,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,dalfampridine,DB06637
,38497,DB00068,10022081,62,2172,24,641,0.296849962,0.762468951,0.464657263,1.288322338,0.462683897,DB0006810022081_,0.770711185,-0.271193491,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,38499,DB00316,10022081,99,65375,21,36932,9.74007978793059e-06,2.66318792,1.650370484,4.492652687,0.000106187,DB0031610022081_,9.150304413,0.979523871,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,38500,DB00635,10022081,71,32982,18,23776,2.10245819352263e-05,2.843367926,1.676128919,5.071645811,0.000208383,DB0063510022081_,8.476133875,1.044989239,female,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,38508,DB00181,10047942,105,9751,38,5833,0.007041091,1.652857175,1.128695504,2.466600913,0.026918055,DB0018110047942_,3.614958017,0.502505412,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,baclofen,DB00181
,38510,DB01062,10047942,58,4428,15,1730,0.189241781,1.510655546,0.842217234,2.878047659,0.335608421,DB0106210047942_,1.091810211,0.412543693,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,oxybutynin,DB01062
,38511,DB01068,10047942,98,13665,58,6782,0.305923594,0.838602948,0.599167324,1.182782509,0.472803274,DB0106810047942_,0.749075889,-0.176017929,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,clonazepam,DB01068
,38512,DB06637,10047942,82,6080,12,2007,0.005468401,2.255630071,1.220851397,4.552227065,0.021973083,DB0663710047942_,3.817937093,0.813429345,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,dalfampridine,DB06637
,38516,DB00635,10051572,58,32995,10,23784,1.78859595242222e-06,4.180739466,2.118059308,9.17787224,2.39863492905194e-05,DB0063510051572_,10.63802567,1.430488137,female,10051572,Injection site discolouration,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,38526,DB00374,10028334,223,17493,68,5656,0.731438207,1.060311376,0.803368621,1.414853682,0.843831341,DB0037410028334_,0.169802638,0.058562616,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,38527,DB00682,10028334,272,19187,153,16211,5.63224689287612e-05,1.502015018,1.226233433,1.845348801,0.000488915,DB0068210028334_,7.623320911,0.406807552,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,38528,DB06403,10028334,244,21227,49,6612,0.004516535,1.551033316,1.13573699,2.156371222,0.018824564,DB0640310028334_,3.972592662,0.438921364,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,38529,DB00203,10033371,743,13135,259,8679,1.32903939120174e-19,1.895463649,1.638851255,2.197650405,1.3282813839444e-17,DB0020310033371_,38.86006067,0.639463478,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,38531,DB00682,10041569,41,19418,32,16332,0.814439089,1.077650122,0.661874547,1.76876398,0.900478746,DB0068210041569_,0.104828717,0.074782857,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,38534,DB00374,10048334,50,17666,14,5710,0.770778276,1.15434723,0.627709837,2.262864914,0.874483718,DB0037410048334_,0.134121604,0.143535016,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,38535,DB00682,10048334,58,19401,28,16336,0.016690312,1.744150258,1.092291392,2.845846621,0.053608461,DB0068210048334_,2.92604837,0.556267479,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,38537,DB00203,10064684,154,13724,58,8880,0.000384672,1.71796642,1.260796888,2.368650234,0.002483077,DB0020310064684_,5.99825661,0.541141277,NA,10064684,Device dislocation,10077536,Product issues,Prod,sildenafil,DB00203
,38538,DB00682,10064684,119,19340,28,16336,1.77619161673359e-11,3.589643143,2.360866148,5.633380092,6.50692636178988e-10,DB0068210064684_,21.15298373,1.278052795,female,10064684,Device dislocation,10077536,Product issues,Prod,warfarin,DB00682
,38539,DB06403,10064684,142,21329,28,6633,0.029392318,1.57707627,1.044825067,2.46015397,0.083350639,DB0640310064684_,2.484699002,0.455572671,NA,10064684,Device dislocation,10077536,Product issues,Prod,ambrisentan,DB06403
,38540,DB00476,10021036,58,17199,23,6154,0.70478545,0.902301097,0.547451801,1.534134882,0.822943697,DB0047610021036_,0.194867493,-0.102807004,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,duloxetine,DB00476
,38541,DB00480,10021036,41,67387,53,67609,0.256343816,0.776136897,0.5033099,1.189290982,0.417174703,DB0048010021036_,0.874250193,-0.25342636,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,38542,DB00787,10021036,47,16953,40,17208,0.452918058,1.192666113,0.765210541,1.866956913,0.620550505,DB0078710021036_,0.477148284,0.176191232,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,acyclovir,DB00787
,38543,DB01015,10021036,75,9812,76,9305,0.743856043,0.935883456,0.670172101,1.306589955,0.853623929,DB0101510021036_,0.158264547,-0.066264323,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,sulfamethoxazole,DB01015
,38544,DB00476,10029331,206,17051,138,6039,2.2353859041575e-08,0.528737808,0.423201556,0.662133715,4.63384215226971e-07,DB0047610029331_,14.58470929,-0.637262608,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,38545,DB00476,10046555,33,17224,19,6158,0.113792428,0.620977575,0.342604934,1.156754206,0.231836141,DB0047610046555_,1.461724445,-0.476460309,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,duloxetine,DB00476
,38546,DB00480,10046555,34,67394,73,67589,0.000205676,0.467105905,0.301346463,0.710996597,0.001474683,DB0048010046555_,6.51931192,-0.76119927,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,38547,DB00695,10046555,45,28004,61,20467,0.001585037,0.539177423,0.358290091,0.805986686,0.008036011,DB0069510046555_,4.823822515,-0.617710591,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,38549,DB00996,10046555,79,38874,72,22353,0.005148114,0.630950047,0.452409869,0.881092098,0.020937215,DB0099610046555_,3.866227086,-0.460528585,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,38550,DB01015,10046555,20,9867,30,9351,0.12004564,0.631822533,0.33982067,1.15088708,0.241441553,DB0101510046555_,1.421127852,-0.459146726,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,sulfamethoxazole,DB01015
,38551,DB00476,10047571,155,17102,36,6141,0.016756988,1.545951249,1.068578861,2.290783894,0.053756934,DB0047610047571_,2.923282608,0.435639416,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,duloxetine,DB00476
,38552,DB00480,10047571,207,67221,148,67514,0.001681573,1.404735351,1.131729917,1.747150528,0.008437558,DB0048010047571_,4.775062357,0.339848923,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,lenalidomide,DB00480
,38553,DB00787,10047571,75,16925,45,17203,0.005853408,1.694005426,1.154567301,2.510692731,0.023214911,DB0078710047571_,3.762960483,0.527095799,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,acyclovir,DB00787
,38554,DB01015,10047571,50,9837,17,9364,0.00011813,2.799380384,1.585928634,5.182535407,0.00091988,DB0101510047571_,6.991267784,1.029398101,female,10047571,Visual impairment,10015919,Eye disorders,Eye,sulfamethoxazole,DB01015
,38558,DB06403,10046735,76,21395,23,6638,1,1.025212418,0.635250925,1.71470971,1,DB0640310046735_,0,0.024899829,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,ambrisentan,DB06403
,38561,DB01060,10022116,57,8530,14,5067,0.001920724,2.418374764,1.328852976,4.704114255,0.009417318,DB0106010022116_,4.665204995,0.88309573,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,amoxicillin,DB01060
,38562,DB01060,10033371,292,8295,108,4973,1.55390538622742e-05,1.6208636,1.29163471,2.04630905,0.000159704,DB0106010033371_,8.742185883,0.482959094,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,38564,DB01060,10049119,45,8542,11,5070,0.005485853,2.427968649,1.23501767,5.210012182,0.022029739,DB0106010049119_,3.815361971,0.887054961,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,amoxicillin,DB01060
,38569,DB00966,10012735,34,679,16,418,0.45675852,1.307877012,0.692417018,2.570749775,0.624136916,DB0096610012735_,0.471385519,0.268405221,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,telmisartan,DB00966
,38570,DB00966,10028813,42,671,13,421,0.031732477,2.025920645,1.051686566,4.164109483,0.088503218,DB0096610028813_,2.424716362,0.706024237,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,telmisartan,DB00966
,38571,DB00341,10047895,206,11199,101,4967,0.417423226,0.904618579,0.707791702,1.162321022,0.586524192,DB0034110047895_,0.533541364,-0.100241883,NA,10047895,Weight decreased,10022891,Investigations,Inv,cetirizine,DB00341
,38572,DB00448,10047895,101,5044,65,3059,0.746477189,0.942357659,0.680913707,1.312018254,0.855523435,DB0044810047895_,0.156041793,-0.059370396,NA,10047895,Weight decreased,10022891,Investigations,Inv,lansoprazole,DB00448
,38573,DB01590,10047895,140,4598,117,2750,0.010522908,0.715712133,0.553257666,0.927217776,0.037079514,DB0159010047895_,3.294690649,-0.334477242,NA,10047895,Weight decreased,10022891,Investigations,Inv,everolimus,DB01590
,38580,DB00126,10047571,89,10082,24,5921,0.000394668,2.177749543,1.372786524,3.579675993,0.002533918,DB0012610047571_,5.977988482,0.778292024,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,ascorbic acid,DB00126
,38581,DB00177,10047571,36,4764,18,2832,0.576088009,1.188930259,0.656252292,2.228387009,0.725446856,DB0017710047571_,0.32096746,0.173053961,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,valsartan,DB00177
,38582,DB00338,10047571,209,33465,96,22176,0.002745464,1.442661649,1.126955064,1.857976228,0.012574407,DB0033810047571_,4.376091691,0.366489775,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,omeprazole,DB00338
,38583,DB13961,10047571,81,9376,39,6375,0.076873949,1.412126535,0.951034354,2.128585713,0.172983583,DB1396110047571_,1.754558585,0.345096749,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,fish oil,DB13961
,38585,DB06403,10061105,68,21403,30,6631,0.120914035,0.702260387,0.450282273,1.119093129,0.242779421,DB0640310061105_,1.415601979,-0.353451022,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,ambrisentan,DB06403
,38590,DB00213,10008531,171,18724,111,13310,0.467175696,1.09511621,0.856409721,1.404965225,0.633719224,DB0021310008531_,0.456149288,0.090860485,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,38591,DB00213,10013496,38,18857,17,13404,0.131633403,1.588875255,0.874928891,3.003441377,0.25806836,DB0021310013496_,1.354530768,0.463026379,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,38592,DB00497,10013496,39,19228,38,16337,0.568554925,0.872010017,0.543040169,1.401383474,0.719573691,DB0049710013496_,0.329096339,-0.136954367,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,38594,DB00213,10013709,703,18192,378,13043,8.05876980519033e-06,1.333387628,1.172567734,1.51814285,9.00998572222151e-05,DB0021310013709_,9.314591978,0.287722792,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,38600,DB00213,10033295,30,18865,45,13376,0.001422497,0.472697424,0.287375436,0.767464089,0.007355958,DB0021310033295_,4.912244622,-0.749299791,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,38616,DB00374,10049848,55,17661,13,5711,0.395826703,1.368060015,0.737204154,2.731937448,0.565466718,DB0037410049848_,0.570103839,0.313393689,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,38617,DB00820,10049848,57,11858,25,5791,0.724224261,1.113454978,0.683696919,1.861959938,0.837991534,DB0082010049848_,0.176747281,0.107467774,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,38623,DB08899,10013968,6,243,225,7908,1,0.867830916,0.312004208,1.946690212,1,DB0889910013968_,0,-0.141758381,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enzalutamide,DB08899
,38624,DB08899,10019211,13,236,196,7937,0.01104778,2.230397578,1.149483304,3.978722788,0.038531269,DB0889910019211_,3.256285195,0.802179856,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,enzalutamide,DB08899
,38627,DB00682,10062237,76,19383,87,16277,0.049128253,0.733592445,0.531675372,1.010345554,0.123348005,DB0068210062237_,2.092745607,-0.309801656,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,warfarin,DB00682
,38628,DB00399,10000060,55,6937,39,4959,1,1.008138715,0.655655024,1.563480497,1,DB0039910000060_,0,0.008105774,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,38629,DB00480,10000060,283,67145,232,67430,0.024254243,1.225001189,1.025797645,1.464057097,0.071833553,DB0048010000060_,2.633403594,0.202941815,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,38630,DB00950,10000060,45,4673,13,2043,0.200142076,1.513288841,0.80013841,3.064602655,0.349167654,DB0095010000060_,1.052203088,0.414285323,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,fexofenadine,DB00950
,38631,DB01373,10000060,155,22565,40,7341,0.210536003,1.260623635,0.884532759,1.834251041,0.361831414,DB0137310000060_,1.016576884,0.231606547,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,38632,DB00480,10005724,617,66811,282,67380,5.38944806457557e-30,2.206553438,1.912678774,2.550502886,1.19545689769932e-27,DB0048010005724_,61.99126906,0.791431768,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,38634,DB01373,10005724,102,22618,41,7340,0.243438777,0.807340066,0.556144529,1.191354325,0.401786422,DB0137310005724_,0.911834619,-0.214010304,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,calcium,DB01373
,38635,DB00399,10011224,160,6832,76,4922,0.002672652,1.516649197,1.144200573,2.02512338,0.012303326,DB0039910011224_,4.397885683,0.416503426,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zoledronic acid,DB00399
,38636,DB00480,10011224,791,66637,617,67045,2.35455050109548e-06,1.289853009,1.158848948,1.436181821,3.05249617367668e-05,DB0048010011224_,10.39696579,0.254528265,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,38637,DB00950,10011224,151,4567,57,1999,0.399435696,1.159501216,0.845416178,1.609042757,0.569291976,DB0095010011224_,0.563361837,0.147989927,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fexofenadine,DB00950
,38638,DB01373,10011224,475,22245,129,7252,0.069481734,1.200396811,0.98423884,1.472504429,0.160372607,DB0137310011224_,1.830255376,0.182652178,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,38639,DB00316,10062244,177,65297,70,36883,0.011588135,1.428258228,1.076784218,1.912241775,0.040054458,DB0031610062244_,3.217515308,0.356455679,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,38641,DB00480,10062244,231,67197,125,67537,1.46536349848614e-08,1.857330476,1.487281624,2.328457218,3.17078055312796e-07,DB0048010062244_,14.96411786,0.619140229,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,38643,DB01373,10062244,79,22641,27,7354,0.821271646,0.950364505,0.606517558,1.531934327,0.904741207,DB0137310062244_,0.100106335,-0.050909678,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,38659,DB01273,10000125,98,1942,79,1196,0.095165367,0.764056044,0.557109248,1.050534973,0.203458593,DB0127310000125_,1.59229277,-0.269114136,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,varenicline,DB01273
,38660,DB00215,10003285,40,11063,15,5261,0.473258972,1.268075663,0.684659613,2.473457292,0.639210757,DB0021510003285_,0.447521055,0.237500525,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,38661,DB00999,10003285,128,21302,41,12198,0.000958666,1.787669285,1.247701256,2.609199879,0.005320637,DB0099910003285_,5.236162304,0.580912696,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,38664,DB00999,10016766,83,21347,50,12189,0.786672779,0.947851273,0.658968357,1.375594252,0.88426195,DB0099910016766_,0.123001937,-0.053557674,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,38666,DB00215,10042209,52,11051,12,5264,0.022083778,2.064048049,1.08613656,4.252088366,0.066824624,DB0021510042209_,2.705683637,0.724669127,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,38667,DB00788,10042209,65,9291,7,5054,1.2908973379918e-06,5.051494189,2.314773101,13.06905087,1.79672949584933e-05,DB0078810042209_,10.9269574,1.619684079,female,10042209,Stress,10037175,Psychiatric disorders,Psych,naproxen,DB00788
,38668,DB00999,10042209,90,21340,27,12212,0.0026903,1.907493998,1.228077417,3.053239944,0.012372417,DB0099910042209_,4.392285753,0.645790338,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,38670,DB08932,10007882,244,19199,88,6509,0.61183868,0.940029496,0.732536703,1.215607436,0.753846284,DB0893210007882_,0.282566799,-0.061844026,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,macitentan,DB08932
,38671,DB00073,10039073,111,7295,12,6395,1.26518501068662e-18,8.107859795,4.455465016,16.18176087,1.16074652725647e-16,DB0007310039073_,36.69229813,2.092833936,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,rituximab,DB00073
,38672,DB00635,10039073,855,32198,205,23589,1.45233242304795e-55,3.055455865,2.618029058,3.579552987,1.07533965464269e-52,DB0063510039073_,119.6617883,1.116928801,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,38673,DB08932,10039073,58,19385,8,6589,0.010680485,2.464366393,1.170308274,5.978815417,0.037521591,DB0893210039073_,3.282838758,0.901934733,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,38676,DB08932,10039710,126,19317,14,6583,8.63431349254136e-06,3.067137026,1.760025244,5.774967957,9.55342171685522e-05,DB0893210039710_,9.25602608,1.120744562,female,10039710,Scleroderma,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,38677,DB08932,10043554,53,19390,22,6575,0.426071481,0.816892174,0.48794475,1.411673485,0.594773566,DB0893210043554_,0.519574506,-0.202248171,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,macitentan,DB08932
,38678,DB00635,10055798,124,32929,104,23690,0.253444461,0.857783092,0.655272091,1.124741184,0.413968473,DB0063510055798_,0.881965459,-0.153404017,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,prednisone,DB00635
,38682,DB00877,10053762,166,942,244,1187,0.173998512,0.857323185,0.686817433,1.068377272,0.316158641,DB0087710053762_,1.151511163,-0.15394032,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sirolimus,DB00877
,38687,DB00008,10035528,65,1460,78,1598,0.608261116,0.912146326,0.64082436,1.294695883,0.751004906,DB0000810035528_,0.286343095,-0.091954856,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,peginterferon alfa-2a,DB00008
,38715,DB00425,10005483,40,12655,42,7442,0.011236353,0.560107141,0.353642138,0.885809024,0.039080226,DB0042510005483_,3.242138671,-0.57962719,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,zolpidem,DB00425
,38716,DB00433,10005483,48,7608,49,5971,0.21814722,0.76883558,0.504685301,1.170668169,0.371334457,DB0043310005483_,0.990652121,-0.262878142,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,prochlorperazine,DB00433
,38717,DB00476,10005483,49,17208,24,6153,0.230432132,0.730041725,0.438969872,1.245177766,0.38644213,DB0047610005483_,0.950773151,-0.31465359,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,duloxetine,DB00476
,38718,DB00736,10005483,31,10560,34,5519,0.003636254,0.476531213,0.282909128,0.799987987,0.015799475,DB0073610005483_,4.147778542,-0.741222052,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,esomeprazole,DB00736
,38720,DB00811,10005483,20,2778,44,4112,0.159447601,0.672855966,0.37484513,1.168836863,0.296709917,DB0081110005483_,1.215000329,-0.396223989,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,ribavirin,DB00811
,38721,DB01075,10005483,49,19899,58,11039,0.000105503,0.468673111,0.313479075,0.698167039,0.000835665,DB0107510005483_,7.087283102,-0.757849744,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,diphenhydramine,DB01075
,38724,DB08934,10005483,7,4482,44,6160,2.19521829533911e-05,0.218677618,0.083025375,0.489979907,0.000216424,DB0893410005483_,8.438272146,-1.520156696,male,10005483,Blood creatinine increased,10022891,Investigations,Inv,sofosbuvir,DB08934
,38725,DB00321,10013573,243,7204,64,2786,0.006434931,1.468365904,1.106460044,1.972515703,0.02503399,DB0032110013573_,3.687520787,0.384150153,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,38726,DB00370,10013573,117,4424,86,3577,0.520799298,1.100020468,0.822522965,1.475857169,0.679854463,DB0037010013573_,0.385876529,0.095328787,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,mirtazapine,DB00370
,38727,DB00741,10013573,139,3955,78,3096,0.021692879,1.394937003,1.045175445,1.872796849,0.065934009,DB0074110013573_,2.719100896,0.332849255,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,hydrocortisone,DB00741
,38731,DB00425,10021036,37,12658,28,7456,0.367959363,0.778391655,0.463190735,1.321635196,0.537666391,DB0042510021036_,0.620517003,-0.250525468,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,zolpidem,DB00425
,38732,DB00433,10021036,60,7596,54,5966,0.507538806,0.872691866,0.593079941,1.286799428,0.668168762,DB0043310021036_,0.403214499,-0.136172745,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,prochlorperazine,DB00433
,38733,DB00741,10021036,39,4055,41,3133,0.1753,0.734976655,0.460502548,1.171290264,0.317828904,DB0074110021036_,1.146242079,-0.307916542,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,hydrocortisone,DB00741
,38738,DB00060,10060933,46,9462,9,2456,0.507098398,1.326628821,0.64045106,3.087160102,0.667732008,DB0006010060933_,0.403868372,0.282641003,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,38739,DB00316,10003997,65,65409,75,36878,2.8982701641207e-05,0.488624827,0.344966312,0.690579301,0.000275121,DB0031610003997_,8.198299211,-0.716160309,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,38741,DB00480,10003997,37,67391,62,67600,0.015410102,0.598630822,0.387193517,0.91398031,0.050354866,DB0048010003997_,2.988660022,-0.513110196,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,38743,DB01015,10003997,28,9859,41,9340,0.090577116,0.64699512,0.384978047,1.072817141,0.196154026,DB0101510003997_,1.628855083,-0.435416527,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,38752,DB00678,10074903,84,15515,30,10694,0.001539563,1.929899173,1.257341735,3.036337978,0.007859278,DB0067810074903_,4.846060551,0.657467759,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,38753,DB01076,10074903,106,25641,79,25504,0.055429171,1.334591194,0.987382262,1.810211905,0.135042344,DB0107610074903_,2.002166887,0.288625023,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,38768,DB00005,10017955,48,128034,22,42397,0.213622246,0.72248592,0.427722274,1.257032581,0.365773943,DB0000510017955_,1.005739779,-0.325057347,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,38769,DB00005,10030124,199,127883,58,42361,0.427240416,1.136521087,0.84423423,1.550544326,0.595867367,DB0000510030124_,0.517737176,0.127971918,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,38771,DB00451,10012671,91,47180,32,15387,0.753163075,0.927436843,0.613502864,1.435012938,0.861090078,DB0045110012671_,0.14955616,-0.075330581,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,38773,DB00996,10012671,54,38899,24,22401,0.346632103,1.295725099,0.787119748,2.192334045,0.516060411,DB0099610012671_,0.661531445,0.25907046,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,38775,DB06292,10012671,147,1210,135,1098,0.949676377,0.988102191,0.765576691,1.276043786,0.988016765,DB0629210012671_,0.012055613,-0.011969154,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,dapagliflozin,DB06292
,38776,DB00065,10061623,161,9303,50,4907,0.000968659,1.698377502,1.227002211,2.386428158,0.005366468,DB0006510061623_,5.227585299,0.529673384,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,38780,DB00836,10011906,228,5307,239,3836,9.80277711939669e-05,0.689591127,0.569809145,0.834341675,0.000783656,DB0083610011906_,7.151540783,-0.371656426,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,38781,DB00331,10033553,43,24903,31,20721,0.561411992,1.154152283,0.710262908,1.895367036,0.713805322,DB0033110033553_,0.337145012,0.14336612,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,38782,DB00722,10033553,26,25377,46,25986,0.025125754,0.578790777,0.343347836,0.956491712,0.073766383,DB0072210033553_,2.60685216,-0.546814219,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,38788,DB00530,10051398,48,1760,32,1236,0.908493555,1.05339941,0.655419412,1.713359573,0.959026229,DB0053010051398_,0.041836854,0.052022468,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,erlotinib,DB00530
,38789,DB00215,10013709,533,10570,216,5060,0.045311186,1.181238574,1.002897462,1.395102636,0.116178561,DB0021510013709_,2.152626957,0.166563527,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,38790,DB00222,10013709,127,3079,144,2984,0.214599361,0.854755031,0.664278134,1.098784706,0.36700896,DB0022210013709_,1.002369016,-0.156940364,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,38791,DB00727,10013709,202,3641,195,3978,0.2362197,1.131758463,0.920055313,1.39240199,0.393450024,DB0072710013709_,0.932801224,0.123772585,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,38800,DB00294,10013573,225,14146,6,162,0.051782725,0.429491778,0.190182628,1.200213431,0.128388334,DB0029410013573_,2.05269575,-0.845152682,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,etonogestrel,DB00294
,38802,DB00264,10021688,32,29575,31,24861,0.613723369,0.867728638,0.512545541,1.47074647,0.755369411,DB0026410021688_,0.280548363,-0.141876242,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,metoprolol,DB00264
,38806,DB00863,10028596,55,10618,37,5803,0.327144709,0.812425224,0.525238349,1.269449255,0.495562396,DB0086310028596_,0.702062009,-0.207731401,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,ranitidine,DB00863
,38811,DB05259,10002855,185,11085,40,2688,0.55332852,1.12150623,0.790962625,1.62496664,0.70697037,DB0525910002855_,0.346766524,0.11467263,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,glatiramer,DB05259
,38812,DB05259,10013968,494,10776,91,2637,0.014084357,1.328395317,1.055681986,1.686992521,0.046823163,DB0525910013968_,3.061377267,0.283971685,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glatiramer,DB05259
,38813,DB05259,10016825,356,10914,63,2665,0.020325046,1.379782784,1.049115729,1.839826803,0.062599179,DB0525910016825_,2.771003121,0.321926084,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,glatiramer,DB05259
,38819,DB00012,10003988,64,1582,28,1285,0.007391566,1.85622917,1.16524113,3.025426213,0.027969096,DB0001210003988_,3.576655106,0.618547102,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,darbepoetin alfa,DB00012
,38820,DB00745,10003988,65,2512,14,1069,0.017920618,1.975486692,1.091346986,3.829253015,0.056687338,DB0074510003988_,2.870204414,0.680814794,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,modafinil,DB00745
,38821,DB13961,10003988,242,9215,133,6281,0.048894136,1.24019761,0.997055663,1.547996702,0.122907854,DB1396110003988_,2.096320362,0.21527073,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,38840,DB00745,10016173,166,2411,54,1029,0.094077192,1.311950266,0.95058531,1.834287494,0.201862774,DB0074510016173_,1.600167149,0.271514783,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,modafinil,DB00745
,38841,DB01268,10016173,44,2099,41,3089,0.044460705,1.579151837,1.004354791,2.487862586,0.114522969,DB0126810016173_,2.166979875,0.456887891,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sunitinib,DB01268
,38842,DB00012,10018884,72,1574,68,1245,0.337842685,0.837560046,0.587640194,1.194828551,0.50694725,DB0001210018884_,0.679348325,-0.177262321,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,darbepoetin alfa,DB00012
,38844,DB01098,10018884,77,8072,61,7148,0.549221975,1.117776171,0.78717924,1.593258691,0.703578901,DB0109810018884_,0.351575254,0.111341149,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,rosuvastatin,DB01098
,38845,DB01268,10018884,28,2115,33,3097,0.432408773,1.24237583,0.7209343,2.12729011,0.600812189,DB0126810018884_,0.50947289,0.217025538,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,sunitinib,DB01268
,38846,DB00012,10047942,33,1613,18,1295,0.203119956,1.471705766,0.8006602,2.789727621,0.352759038,DB0001210047942_,1.041970067,0.386422113,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,darbepoetin alfa,DB00012
,38847,DB00451,10047942,620,46651,195,15224,0.682337217,1.037608778,0.88097833,1.226419044,0.807857023,DB0045110047942_,0.213370188,0.036918814,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,38848,DB00722,10047942,292,25111,206,25826,3.32207731359255e-05,1.457817461,1.214461701,1.752574839,0.000310364,DB0072210047942_,8.077766006,0.376940428,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,lisinopril,DB00722
,38849,DB00996,10047942,493,38460,273,22152,0.623650975,1.040132568,0.894494498,1.211485531,0.76365722,DB0099610047942_,0.269636256,0.039348175,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,gabapentin,DB00996
,38850,DB01076,10047942,284,25463,219,25364,0.00472672,1.291751708,1.078242175,1.549206698,0.019550249,DB0107610047942_,3.934767264,0.25599921,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,38851,DB01098,10047942,82,8067,55,7154,0.121609501,1.322145996,0.926716071,1.898936476,0.243731662,DB0109810047942_,1.411687407,0.279256171,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,rosuvastatin,DB01098
,38852,DB01268,10047942,57,2086,69,3061,0.312752343,1.212148296,0.834298663,1.75524001,0.480264961,DB0126810047942_,0.733417326,0.192394237,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,sunitinib,DB01268
,38853,DB13961,10047942,177,9280,89,6325,0.019747127,1.355462402,1.042642639,1.772607232,0.061183854,DB1396110047942_,2.793871955,0.304142652,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,fish oil,DB13961
,38863,DB08907,10005483,39,4214,84,3826,6.34771560700166e-06,0.421578335,0.279956128,0.625153255,7.29716618106445e-05,DB0890710005483_,9.525439387,-0.86374967,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,canagliflozin,DB08907
,38864,DB08907,10012174,115,4138,139,3771,0.0299156,0.753991367,0.581366169,0.9763562,0.084529056,DB0890710012174_,2.470659947,-0.282374361,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,canagliflozin,DB08907
,38865,DB00927,10016256,579,6918,273,4743,5.55839629178824e-07,1.454036782,1.250859732,1.693340863,8.5290394938502e-06,DB0092710016256_,11.67203381,0.374343676,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,38866,DB08907,10016256,63,4190,70,3840,0.293944117,0.82484239,0.575677754,1.179764606,0.459667496,DB0890710016256_,0.777251886,-0.192562953,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,canagliflozin,DB08907
,38871,DB08907,10018358,59,4194,87,3823,0.004449889,0.618212975,0.435155244,0.873026395,0.018607276,DB0890710018358_,3.984202576,-0.480922261,NA,10018358,Glomerular filtration rate decreased,10022891,Investigations,Inv,canagliflozin,DB08907
,38872,DB00175,10025482,293,7838,115,5991,6.22020551274008e-10,1.947332704,1.559967383,2.444178987,1.79274234542076e-08,DB0017510025482_,17.83693426,0.666460592,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,38873,DB08907,10025482,53,4200,34,3876,0.105969543,1.438503531,0.915621285,2.287659432,0.220146961,DB0890710025482_,1.513459949,0.363603359,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,canagliflozin,DB08907
,38876,DB00264,10036018,82,29525,82,24810,0.272568878,0.840309623,0.610827743,1.156045126,0.435531388,DB0026410036018_,0.831188412,-0.173984856,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,38878,DB00999,10036018,77,21353,53,12186,0.315101739,0.829133517,0.576412344,1.200514712,0.482688339,DB0099910036018_,0.728384095,-0.18737408,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,hydrochlorothiazide,DB00999
,38879,DB01104,10036018,38,15425,21,7265,0.577173683,0.852282825,0.487236582,1.529757233,0.726267905,DB0110410036018_,0.319836317,-0.159836853,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,sertraline,DB01104
,38880,DB08907,10036018,47,4206,76,3834,0.00194483,0.563769296,0.382224069,0.824031674,0.009518639,DB0890710036018_,4.65450342,-0.573110161,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,canagliflozin,DB08907
,38881,DB00646,10000087,42,3411,19,1981,0.423730736,1.283755521,0.728015737,2.34402897,0.592541487,DB0064610000087_,0.523334388,0.249789783,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,nystatin,DB00646
,38884,DB00715,10013573,177,4666,57,2230,0.010235411,1.484007716,1.090145345,2.045991661,0.036229165,DB0071510013573_,3.317890833,0.394746344,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,paroxetine,DB00715
,38885,DB01211,10013573,31,1621,22,765,0.180306165,0.66510028,0.370085671,1.214346783,0.324224221,DB0121110013573_,1.126319961,-0.407817453,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,clarithromycin,DB01211
,38888,DB00331,10014387,77,24869,48,20704,0.126273929,1.335494423,0.918968114,1.958054173,0.250489433,DB0033110014387_,1.384338543,0.289301577,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,metformin,DB00331
,38894,DB01164,10040070,26,6498,36,7900,0.701602791,0.878067544,0.508503348,1.49692313,0.820850126,DB0116410040070_,0.197414736,-0.130031759,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,calcium chloride,DB01164
,38895,DB00193,10022116,94,19226,17,8685,0.000188438,2.497743838,1.47881193,4.47052062,0.001371291,DB0019310022116_,6.592002572,0.915387859,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,38896,DB00404,10022116,92,19800,18,9844,9.8821960132096e-05,2.541029825,1.520846867,4.478915078,0.000789045,DB0040410022116_,7.144687558,0.932569442,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,38898,DB00669,10033371,276,6101,26,1071,0.001558692,1.863337409,1.236926439,2.918788601,0.007933817,DB0066910033371_,4.836621052,0.622369186,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,38924,DB00997,10043554,162,5169,153,3361,0.001242012,0.688518764,0.546141467,0.868290081,0.006578596,DB0099710043554_,5.023933884,-0.373212708,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,doxorubicin,DB00997
,38925,DB01181,10043554,33,540,54,866,1,0.980053362,0.607096586,1.561775299,1,DB0118110043554_,0,-0.020148258,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,ifosfamide,DB01181
,38932,DB00997,10051055,46,5285,34,3480,0.646723336,0.890881344,0.558273007,1.434356698,0.782126246,DB0099710051055_,0.245739112,-0.115544033,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,doxorubicin,DB00997
,38934,DB00441,10051398,87,2187,48,1846,0.022046064,1.529736429,1.057079089,2.236348599,0.066737394,DB0044110051398_,2.706989856,0.425095452,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,gemcitabine,DB00441
,38936,DB00997,10051398,84,5247,57,3457,0.862687576,0.970928249,0.683436712,1.387971131,0.936336136,DB0099710051398_,0.065780747,-0.029502707,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,doxorubicin,DB00997
,38942,DB00331,10000059,351,24595,209,20543,0.000117756,1.402729246,1.177378646,1.674526973,0.000917647,DB0033110000059_,6.993697586,0.3384198,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,38943,DB00586,10013709,514,6595,184,2621,0.257155443,1.110175657,0.930418361,1.329114574,0.418016748,DB0058610013709_,0.872233781,0.104518253,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,38944,DB00813,10013709,548,10024,375,9793,1.69811990299215e-07,1.427626107,1.245829377,1.637299114,2.93555288721794e-06,DB0081310013709_,12.73861475,0.356013,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,38945,DB11133,10013709,71,2360,54,1520,0.402507431,0.846870533,0.582403519,1.237402181,0.572320016,DB1113310013709_,0.558056975,-0.166207449,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,38946,DB00169,10033295,93,38598,53,18122,0.286117404,0.823870925,0.581486513,1.177815866,0.45083475,DB0016910033295_,0.796654415,-0.193741406,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,38947,DB00586,10033295,52,7057,17,2788,0.591973428,1.208412842,0.686155506,2.233129163,0.738246503,DB0058610033295_,0.303477495,0.189307798,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,diclofenac,DB00586
,38957,DB00169,10069327,98,38593,48,18127,0.790618459,0.958969257,0.671958211,1.384901048,0.886578762,DB0016910069327_,0.120385311,-0.041896262,NA,10069327,Product quality issue,10077536,Product issues,Prod,cholecalciferol,DB00169
,38958,DB00476,10069327,53,17204,14,6163,0.404261347,1.356117402,0.741107169,2.648750864,0.573982045,DB0047610069327_,0.555157163,0.304625765,NA,10069327,Product quality issue,10077536,Product issues,Prod,duloxetine,DB00476
,38962,DB00811,10033371,89,2709,88,4068,0.006501263,1.518590394,1.11350918,2.07144094,0.02524907,DB0081110033371_,3.678965968,0.417782532,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,38968,DB00620,10013700,131,4697,28,3104,3.1728606322701e-09,3.091423451,2.037398828,4.843505174,7.96929208974865e-08,DB0062010013700_,16.34508508,1.128631649,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,triamcinolone,DB00620
,38969,DB01075,10013700,538,19410,111,10986,3.6506996638839e-26,2.743211706,2.229214963,3.400653474,6.09261210572624e-24,DB0107510013700_,53.45496532,1.009129389,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,diphenhydramine,DB01075
,38970,DB01307,10013700,42,2482,25,2044,0.217503309,1.383431384,0.820593642,2.377407063,0.370504811,DB0130710013700_,0.99288885,0.324566923,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,insulin detemir,DB01307
,38971,DB00341,10013709,474,10931,176,4892,0.037459366,1.20525822,1.008205285,1.446017034,0.100502138,DB0034110013709_,2.297576281,0.186693835,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,38972,DB00620,10013709,277,4551,200,2932,0.246044717,0.892306793,0.736701179,1.082207882,0.404986106,DB0062010013709_,0.903902517,-0.113945267,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,38973,DB01307,10013709,78,2446,78,1991,0.219732384,0.814022254,0.58359266,1.135404584,0.37310502,DB0130710013709_,0.985895345,-0.205767575,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,insulin detemir,DB01307
,38980,DB00620,10033371,193,4635,82,3050,0.001053316,1.5487111,1.184905407,2.039126748,0.005753023,DB0062010033371_,5.158029814,0.437423036,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,38989,DB00338,10024384,64,33610,43,22229,0.921687706,0.984375963,0.658263521,1.484865641,0.965406088,DB0033810024384_,0.03520645,-0.015747379,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,omeprazole,DB00338
,38994,DB00126,10043554,57,10114,46,5899,0.102314069,0.722760995,0.480790942,1.091620704,0.214451202,DB0012610043554_,1.539673063,-0.324676685,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,ascorbic acid,DB00126
,38995,DB00399,10043554,86,6906,64,4934,0.803227256,0.960022403,0.685104306,1.351310856,0.8934756,DB0039910043554_,0.112636254,-0.040798658,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,zoledronic acid,DB00399
,38999,DB00005,10074170,94,127988,15,42404,0.005511922,2.07608779,1.196731592,3.856935087,0.022117529,DB0000510074170_,3.8113848,0.730485252,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,39007,DB01394,10070863,41,1399,76,1927,0.152402379,0.743140818,0.492238963,1.108029495,0.287312674,DB0139410070863_,1.2471842,-0.296869727,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,colchicine,DB01394
,39008,DB00047,10023232,47,9238,32,8486,0.21468822,1.349163738,0.842051321,2.187108329,0.36707405,DB0004710023232_,1.002191681,0.299484947,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin glargine,DB00047
,39009,DB00153,10023232,84,7339,20,3419,0.005670664,1.956537387,1.188077368,3.370699699,0.022620629,DB0015310023232_,3.788892981,0.671176271,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,39010,DB00331,10023232,168,24778,82,20670,5.56525263734165e-05,1.709084682,1.303964293,2.255246584,0.000483739,DB0033110023232_,7.633965108,0.535957953,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,39011,DB00437,10023232,57,6864,74,11472,0.173991225,1.287333409,0.893800799,1.845892039,0.316156327,DB0043710023232_,1.151518481,0.252572954,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,allopurinol,DB00437
,39012,DB00451,10023232,424,46847,92,15327,0.000259313,1.507785467,1.199977025,1.911685352,0.001790868,DB0045110023232_,6.325054801,0.410641996,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,39013,DB00635,10023232,488,32565,180,23614,9.67263510004997e-16,1.965884494,1.652251332,2.347456649,6.46056385899769e-14,DB0063510023232_,30.3704747,0.675942268,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,39014,DB14500,10023232,80,7729,25,4048,0.02302224,1.675906797,1.056113799,2.746018768,0.068955145,DB1450010023232_,2.674299059,0.51635439,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,39015,DB00047,10033425,176,9109,122,8396,0.01648987,1.329678436,1.047442442,1.692430086,0.053068409,DB0004710033425_,2.936173457,0.284937135,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin glargine,DB00047
,39016,DB00437,10033425,173,6748,168,11378,5.80702164033194e-07,1.736179417,1.392893729,2.16472525,8.84855442412319e-06,DB0043710033425_,11.63525645,0.551686962,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,allopurinol,DB00437
,39017,DB14500,10033425,235,7574,64,4009,9.5673268763951e-07,1.943465105,1.464202661,2.611077946,1.37682555130602e-05,DB1450010033425_,11.19314494,0.664472517,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,39024,DB01098,10046735,77,8072,53,7156,0.159257954,1.287941864,0.894687411,1.866232865,0.296493174,DB0109810046735_,1.215731081,0.25304549,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,rosuvastatin,DB01098
,39030,DB00108,10000081,49,10145,13,3282,0.656617378,1.219358014,0.650438274,2.453198282,0.790020726,DB0010810000081_,0.235696099,0.198324502,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,natalizumab,DB00108
,39031,DB00108,10003988,116,10078,33,3262,0.565750943,1.137755517,0.765324541,1.733345777,0.71728043,DB0010810003988_,0.332288399,0.129057477,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,natalizumab,DB00108
,39032,DB00108,10008479,86,10108,23,3272,0.501683162,1.210350013,0.755238258,2.013389987,0.663166885,DB0010810008479_,0.410728609,0.190909584,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,39034,DB00108,10052904,46,10148,17,3278,0.659350513,0.874079991,0.49080789,1.62870319,0.791895467,DB0010810052904_,0.233325883,-0.134583385,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,natalizumab,DB00108
,39035,DB00331,10037844,605,24341,418,20334,0.003134164,1.209097659,1.064089658,1.374861185,0.014019995,DB0033110037844_,4.26727077,0.189874345,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,39036,DB06655,10037844,64,3624,42,2077,0.541408322,0.873356392,0.580288041,1.326543615,0.696757215,DB0665510037844_,0.361318257,-0.135411568,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,liraglutide,DB06655
,39038,DB00331,10040831,43,24903,24,20728,0.140158113,1.491276858,0.884565911,2.570148521,0.270086132,DB0033110040831_,1.309014363,0.399632705,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,39040,DB00641,10005470,11,14113,42,12433,2.46620004925111e-06,0.230769276,0.107068342,0.456275052,3.17842943341826e-05,DB0064110005470_,10.35653828,-1.466336872,male,10005470,Blood creatine phosphokinase increased,10022891,Investigations,Inv,simvastatin,DB00641
,39043,DB00222,10047899,60,3146,23,3105,5.93208047154378e-05,2.574479713,1.563473592,4.374340324,0.00051081,DB0022210047899_,7.579512968,0.945647461,NA,10047899,Weight increased,10022891,Investigations,Inv,glimepiride,DB00222
,39044,DB00999,10047899,400,21030,140,12099,2.44727073275448e-07,1.643750675,1.350845395,2.009882177,4.07129817787669e-06,DB0099910047899_,12.41154865,0.496980627,NA,10047899,Weight increased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,39045,DB08895,10047899,653,27461,69,6577,1.36739578929885e-12,2.266605322,1.763678372,2.953301064,6.03053663116113e-11,DB0889510047899_,23.53160002,0.818283259,NA,10047899,Weight increased,10022891,Investigations,Inv,tofacitinib,DB08895
,39046,DB00060,10003658,43,9465,19,2446,0.058087348,0.584889522,0.332901381,1.064762924,0.139844839,DB0006010003658_,1.967221765,-0.536332302,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,interferon beta-1a,DB00060
,39047,DB01238,10005557,42,5208,20,3482,0.242352975,1.403979101,0.804520713,2.529002382,0.400568946,DB0123810005557_,0.914869377,0.33931042,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,aripiprazole,DB01238
,39051,DB01238,10015832,31,5219,42,3460,0.00258654,0.489362539,0.29681221,0.798964524,0.011985404,DB0123810015832_,4.424065683,-0.714651676,NA,10015832,Extrapyramidal disorder,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,39053,DB00334,10029282,51,2798,137,2675,5.48334086234689e-11,0.355958908,0.251724088,0.496699175,1.86696391925891e-09,DB0033410029282_,20.0989523,-1.032939982,male,10029282,Neuroleptic malignant syndrome,10029205,Nervous system disorders,Nerv,olanzapine,DB00334
,39060,DB00334,10038695,40,2809,29,2783,0.226240259,1.36646356,0.823643355,2.292368496,0.381139254,DB0033410038695_,0.964590475,0.312226059,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,olanzapine,DB00334
,39061,DB01104,10038695,80,15383,53,7233,0.061852263,0.709721886,0.49477722,1.025326003,0.146864204,DB0110410038695_,1.918246903,-0.342882096,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,39064,DB00334,10045555,36,2813,45,2767,0.3144713,0.786953198,0.491590945,1.251753186,0.482059727,DB0033410045555_,0.729687258,-0.239586501,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,olanzapine,DB00334
,39065,DB01104,10045555,55,15408,33,7253,0.302677708,0.784584625,0.500049914,1.248343837,0.469027771,DB0110410045555_,0.7570933,-0.242600842,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,39090,DB00028,10043554,35,13423,28,5587,0.012136943,0.520276849,0.307196546,0.888819874,0.041522784,DB0002810043554_,3.181512981,-0.653394207,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,human immunoglobulin g,DB00028
,39095,DB00316,10027590,41,65433,17,36936,0.338780154,1.361402916,0.756445107,2.556239195,0.50786109,DB0031610027590_,0.677547314,0.308515724,NA,10027590,Middle insomnia,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,39099,DB08910,10013538,56,16688,45,17443,0.196212897,1.300731245,0.862350911,1.971768873,0.344473418,DB0891010013538_,1.065738354,0.262926602,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,39101,DB00471,10016256,967,13222,286,5179,3.95741374469481e-05,1.324301491,1.154786645,1.522432196,0.000361057,DB0047110016256_,7.92647377,0.280885144,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,39103,DB00471,10020751,235,13954,55,5410,0.000570924,1.656542909,1.228156094,2.26822488,0.003447446,DB0047110020751_,5.670121755,0.504732846,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,montelukast,DB00471
,39105,DB00669,10020751,60,6317,7,1090,0.388856621,1.478932316,0.672968845,3.846035002,0.558742178,DB0066910020751_,0.582067132,0.391320419,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,sumatriptan,DB00669
,39106,DB00927,10020751,119,7378,46,4970,0.001312542,1.742560417,1.227601033,2.510340663,0.006886946,DB0092710020751_,4.978127579,0.555355536,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,famotidine,DB00927
,39107,DB01050,10020751,189,17919,70,9301,0.017563591,1.401440216,1.058626702,1.873235549,0.055830088,DB0105010020751_,2.885442335,0.337500433,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ibuprofen,DB01050
,39108,DB01175,10020751,106,10618,23,4869,0.000773947,2.113281359,1.334665205,3.48182604,0.004450003,DB0117510020751_,5.41485054,0.748241886,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,escitalopram,DB01175
,39120,DB00273,10037377,60,8421,14,2179,0.885115596,1.108951483,0.611036242,2.153051484,0.952148128,DB0027310037377_,0.04903466,0.103414959,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,topiramate,DB00273
,39126,DB00169,10022061,351,38340,42,18133,4.46767661986196e-23,3.952032202,2.863023896,5.58387067,6.10040934821151e-21,DB0016910022061_,46.54593108,1.374229928,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,39127,DB00338,10022061,238,33436,49,22223,8.65500793542574e-17,3.228182452,2.364218831,4.487371121,6.47217307489803e-15,DB0033810022061_,32.67126447,1.17191927,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,39129,DB05259,10022061,752,10518,144,2584,0.007780915,1.282935268,1.066236607,1.552240045,0.029120833,DB0525910022061_,3.536301459,0.249150631,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,39131,DB05679,10013709,919,6012,596,4313,0.073961968,1.106147557,0.989371682,1.237416479,0.168123003,DB0567910013709_,1.78305941,0.10088331,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,39134,DB00065,10021789,131,9333,48,4909,0.032523158,1.435461498,1.021917989,2.046041266,0.090238161,DB0006510021789_,2.405302872,0.361486399,NA,10021789,Infection,10021881,Infections and infestations,Infec,infliximab,DB00065
,39135,DB05679,10021789,70,6861,47,4862,0.850516302,1.055429426,0.717564199,1.564580941,0.926147896,DB0567910021789_,0.076721342,0.053947723,NA,10021789,Infection,10021881,Infections and infestations,Infec,ustekinumab,DB05679
,39141,DB00476,10022052,64,17193,7,6170,0.001015431,3.281116186,1.502810591,8.491903489,0.00557448,DB0047610022052_,5.189556263,1.188183665,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,39143,DB00904,10022052,39,23030,11,14445,0.019090745,2.223750105,1.116455116,4.816368353,0.059571466,DB0090410022052_,2.820578579,0.799195007,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,39144,DB00924,10022052,47,10115,6,4245,0.002347977,3.286919621,1.401183795,9.414775859,0.011083159,DB0092410022052_,4.502328532,1.189950841,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,39146,DB01076,10022052,95,25652,27,25556,4.46627415979872e-10,3.50494858,2.264676303,5.595257498,1.32054011575151e-08,DB0107610022052_,18.14263991,1.25417585,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,39151,DB00904,10050584,181,22888,69,14387,0.000320728,1.648868459,1.241907529,2.21038888,0.002130755,DB0090410050584_,6.151278925,0.50008927,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,39152,DB00924,10050584,103,10059,32,4219,0.154907058,1.349952191,0.898519977,2.078756939,0.290667301,DB0092410050584_,1.235575961,0.300069178,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,39153,DB01076,10050584,209,25538,138,25445,0.000192919,1.508957482,1.210370458,1.886108412,0.001397514,DB0107610050584_,6.573060257,0.411419003,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,39171,DB00956,10013573,200,5614,89,3378,0.018928318,1.352114905,1.044089871,1.762455864,0.059162952,DB0095610013573_,2.827459742,0.301669963,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,39172,DB00956,10013781,40,5774,17,3450,0.273034821,1.40584725,0.777710438,2.649010591,0.436022982,DB0095610013781_,0.830060325,0.340640146,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,hydrocodone,DB00956
,39173,DB00956,10016322,130,5684,50,3417,0.007984342,1.562947592,1.116408179,2.217665696,0.02974115,DB0095610016322_,3.515223657,0.44657352,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,39174,DB00956,10010774,120,5694,54,3413,0.082431305,1.331966708,0.955419557,1.877626151,0.182421121,DB0095610010774_,1.701437414,0.286656578,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,hydrocodone,DB00956
,39175,DB00956,10037844,129,5685,60,3407,0.111096716,1.288430847,0.938422739,1.786252068,0.227720761,DB0095610037844_,1.479635134,0.25342508,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocodone,DB00956
,39195,DB01098,10028391,48,8101,26,7183,0.046835431,1.636892236,0.994232131,2.75165568,0.119145348,DB0109810028391_,2.12741112,0.492799466,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,39196,DB01156,10028391,55,13567,12,6316,0.017142576,2.133662119,1.127975841,4.380852462,0.054746986,DB0115610028391_,2.905032966,0.757839808,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,39202,DB00927,10008479,147,7350,92,4924,0.641206462,1.070440423,0.817146207,1.408250359,0.777959881,DB0092710008479_,0.251080323,0.068070174,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,39203,DB00285,10008479,121,10830,33,3685,0.305446966,1.247587293,0.841229849,1.896904241,0.472219356,DB0028510008479_,0.750311664,0.22121152,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,39208,DB00927,10000081,196,7301,77,4939,4.55844865927939e-05,1.721881525,1.312905349,2.277238189,0.000408123,DB0092710000081_,7.803942851,0.543417603,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,39209,DB00722,10035664,683,24720,754,25278,0.15616302,0.926310551,0.832693363,1.030251339,0.292329522,DB0072210035664_,1.229873613,-0.076545732,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,lisinopril,DB00722
,39210,DB14500,10035664,392,7417,253,3820,0.007176875,0.79802901,0.676230627,0.943022926,0.02731796,DB1450010035664_,3.600210929,-0.225610329,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,potassium,DB14500
,39211,DB01254,10035528,26,3441,49,3099,0.002320062,0.477930968,0.284371045,0.786386015,0.010978008,DB0125410035528_,4.511861272,-0.738288975,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,dasatinib,DB01254
,39213,DB00635,10008111,40,33013,56,23738,0.001252976,0.513624343,0.333410176,0.784816079,0.006624559,DB0063510008111_,5.016971408,-0.66626313,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,39214,DB00682,10008111,108,19351,148,16216,0.000114499,0.611524585,0.472253221,0.78974899,0.000895716,DB0068210008111_,7.017886776,-0.49180012,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,39217,DB01024,10011906,80,2131,98,2022,0.107717907,0.774620259,0.565513644,1.058527156,0.222691978,DB0102410011906_,1.501965727,-0.255382358,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,mycophenolic acid,DB01024
,39218,DB00635,10017577,492,32561,193,23601,9.41084737092323e-14,1.847709706,1.559832921,2.195798201,4.84552640831963e-12,DB0063510017577_,26.05296523,0.613946875,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,39219,DB00864,10017577,37,6832,32,8360,0.181821899,1.414802449,0.856506768,2.348667579,0.326216037,DB0086410017577_,1.120195426,0.346989909,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,39221,DB00864,10028372,23,6846,38,8354,0.302341767,0.738602721,0.419652764,1.273394354,0.46871444,DB0086410028372_,0.757761565,-0.302995092,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,tacrolimus,DB00864
,39223,DB00864,10033425,55,6814,46,8346,0.057163954,1.464418348,0.970499148,2.218814265,0.138115132,DB0086410033425_,1.979667654,0.381458131,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,tacrolimus,DB00864
,39238,DB00567,10010774,89,4430,39,2042,0.847974177,1.051898727,0.71139515,1.580551271,0.923978827,DB0056710010774_,0.079066122,0.050596843,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,cephalexin,DB00567
,39239,DB00635,10010774,410,32643,263,23531,0.145971142,1.123807308,0.959302254,1.318236972,0.27840594,DB0063510010774_,1.278675016,0.116722303,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,39241,DB00916,10010774,84,5239,24,2407,0.046579244,1.607946415,1.008324011,2.654643287,0.1186544,DB0091610010774_,2.131540214,0.474957846,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,metronidazole,DB00916
,39242,DB01222,10010774,127,9147,60,5345,0.194628451,1.2368057,0.901111601,1.713979809,0.342549722,DB0122210010774_,1.071338457,0.212532007,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,39245,DB00196,10019211,246,4837,67,3218,1.01453092442494e-11,2.442450225,1.849940418,3.262090791,3.87319467661723e-10,DB0019610019211_,21.67177127,0.893001726,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,fluconazole,DB00196
,39246,DB00443,10019211,160,1986,56,1134,0.001978136,1.631195455,1.184784079,2.273102525,0.009639473,DB0044310019211_,4.641888874,0.489313154,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,betamethasone,DB00443
,39247,DB00567,10019211,168,4351,43,2038,0.000285921,1.829871437,1.296204993,2.632463412,0.001939954,DB0056710019211_,6.245091106,0.604245711,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cephalexin,DB00567
,39248,DB00878,10019211,57,1129,26,894,0.023537348,1.735544581,1.063598234,2.900659374,0.070141057,DB0087810019211_,2.657246964,0.551321243,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,chlorhexidine,DB00878
,39249,DB01222,10019211,566,8708,163,5242,9.89217236440368e-18,2.090192441,1.746754361,2.512051178,8.25446827296351e-16,DB0122210019211_,34.73060683,0.737256139,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,39250,DB11750,10019211,228,2272,90,1423,0.000287241,1.586504048,1.225981776,2.066794903,0.001947667,DB1175010019211_,6.241122945,0.461532883,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,clobetasol,DB11750
,39251,DB00196,10022437,71,5012,19,3266,0.000300195,2.434822945,1.447775941,4.287628627,0.002018798,DB0019610022437_,6.205252973,0.889874041,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,fluconazole,DB00196
,39252,DB00567,10022437,63,4456,29,2052,1,1.000402346,0.632597094,1.616381372,1,DB0056710022437_,0,0.000402265,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,cephalexin,DB00567
,39254,DB00916,10022437,51,5272,19,2412,0.518219154,1.22800268,0.710800078,2.207619558,0.677546283,DB0091610022437_,0.389277415,0.205389012,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,metronidazole,DB00916
,39255,DB01222,10022437,125,9149,59,5346,0.191345074,1.237922158,0.899540837,1.720385941,0.338254441,DB0122210022437_,1.083956883,0.213434295,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,budesonide,DB01222
,39257,DB11750,10022437,36,2464,15,1498,0.246580672,1.458960323,0.775974072,2.878461452,0.405668959,DB1175010022437_,0.902217824,0.377724074,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,clobetasol,DB11750
,39261,DB00437,10000891,17,6904,39,11507,0.333231236,0.726528888,0.385070247,1.315932723,0.502278466,DB0043710000891_,0.6886006,-0.319477033,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,allopurinol,DB00437
,39265,DB00425,10007559,66,12629,54,7430,0.087508095,0.719101997,0.493636935,1.05142727,0.190978934,DB0042510007559_,1.65559215,-0.329752072,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,zolpidem,DB00425
,39266,DB00924,10007559,42,10120,26,4225,0.141531423,0.674426989,0.403356873,1.14737994,0.271965593,DB0092410007559_,1.302079717,-0.393891854,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,cyclobenzaprine,DB00924
,39267,DB01156,10007559,52,13570,37,6291,0.051974327,0.651549131,0.418840996,1.022748312,0.128749249,DB0115610007559_,2.04988857,-0.428402474,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,bupropion,DB01156
,39269,DB00437,10020772,85,6836,119,11427,0.216956402,1.193972092,0.891553728,1.593285991,0.369848631,DB0043710020772_,0.994661464,0.177285641,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,allopurinol,DB00437
,39270,DB00584,10020772,42,2039,28,1846,0.22856947,1.357911603,0.818330045,2.284762774,0.384115371,DB0058410020772_,0.956812327,0.305947933,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,enalapril,DB00584
,39271,DB00924,10020772,113,10049,41,4210,0.477644588,1.154641839,0.799489624,1.696715999,0.642950171,DB0092410020772_,0.441688052,0.1437902,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,cyclobenzaprine,DB00924
,39280,DB00425,10008190,71,12624,61,7423,0.037161073,0.684439917,0.478594828,0.981245456,0.099890455,DB0042510008190_,2.303681147,-0.379154415,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,39281,DB05259,10013573,347,10923,61,2667,0.018787598,1.388891987,1.05160193,1.860750778,0.058821037,DB0525910013573_,2.833255724,0.328506297,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,39282,DB05259,10033557,183,11087,36,2692,0.264906298,1.23424853,0.857201643,1.821793697,0.426841295,DB0525910033557_,0.85134301,0.210462308,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,glatiramer,DB05259
,39284,DB00108,10003239,84,10110,22,3273,0.427703897,1.236068665,0.764081911,2.080057904,0.596276489,DB0010810003239_,0.517050812,0.211935912,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,natalizumab,DB00108
,39287,DB00928,10037660,33,802,55,1231,0.739576338,0.920969204,0.573827513,1.45824646,0.85016024,DB0092810037660_,0.16233043,-0.082328681,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,azacitidine,DB00928
,39300,DB00688,10047895,107,6383,86,5292,0.884142509,1.031528197,0.767433954,1.389893152,0.951724547,DB0068810047895_,0.049479627,0.031041389,NA,10047895,Weight decreased,10022891,Investigations,Inv,mycophenolate mofetil,DB00688
,39306,DB01222,10043521,46,9228,15,5390,0.046916011,1.791148788,0.980919517,3.457094576,0.119298381,DB0122210043521_,2.126127523,0.582857195,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,39307,DB00264,10008118,36,29571,18,24874,0.075862911,1.682303807,0.930363362,3.147780016,0.171273921,DB0026410008118_,1.764491127,0.520164168,NA,10008118,Cerebral infarction,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,39323,DB00404,10048294,84,19808,45,9817,0.707852157,0.925138754,0.636117152,1.361167013,0.825424513,DB0040410048294_,0.191857463,-0.077811548,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,39324,DB00761,10048294,90,15217,76,8549,0.009447914,0.665338639,0.484188256,0.916226523,0.034014302,DB0076110048294_,3.380974183,-0.407459136,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,potassium chloride,DB00761
,39325,DB01076,10048294,122,25625,142,25441,0.21711248,0.852989316,0.663684011,1.094922845,0.370034861,DB0107610048294_,0.994158059,-0.159008256,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,39326,DB06228,10048294,38,15874,47,16029,0.385569096,0.816411773,0.517693232,1.280015177,0.555660053,DB0622810048294_,0.587598588,-0.202836428,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,rivaroxaban,DB06228
,39328,DB11089,10048294,90,10085,91,8316,0.177318228,0.815541688,0.601637939,1.105371019,0.32039662,DB1108910048294_,1.138195615,-0.203902738,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,docusate,DB11089
,39329,DB00264,10061256,43,29564,36,24856,1,1.004231884,0.629713603,1.60997888,1,DB0026410061256_,0,0.004222955,NA,10061256,Ischaemic stroke,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,39334,DB01076,10061256,38,25709,53,25530,0.116046351,0.711996938,0.456504495,1.100972476,0.235233927,DB0107610061256_,1.447174825,-0.339681668,NA,10061256,Ischaemic stroke,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,39335,DB06228,10061256,65,15847,70,16006,0.730703054,0.937864953,0.658216503,1.334756895,0.843350648,DB0622810061256_,0.170372454,-0.064149314,NA,10061256,Ischaemic stroke,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,39344,DB00761,10000891,54,15253,40,8585,0.197127126,0.759862627,0.495098676,1.174878201,0.345570663,DB0076110000891_,1.062558134,-0.274617616,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,39351,DB00635,10047302,21,33032,47,23747,6.40606224726931e-06,0.321220622,0.182339187,0.548208021,7.34496602702176e-05,DB0063510047302_,9.518910281,-1.135627095,male,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,prednisone,DB00635
,39352,DB00761,10047302,21,15286,50,8575,5.6274140609064e-09,0.235625956,0.134329776,0.399797594,1.33619312186924e-07,DB0076110047302_,15.82827103,-1.445509662,male,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,39353,DB01109,10047302,27,4385,59,4211,0.000306626,0.439506151,0.267394376,0.705709447,0.002054135,DB0110910047302_,6.187900667,-0.822103568,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,heparin,DB01109
,39357,DB00374,10064355,78,17638,23,5701,0.816419848,1.09614135,0.680292651,1.831116839,0.901701572,DB0037410064355_,0.103471665,0.091796149,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,39359,DB00682,10064355,79,19380,71,16293,0.682399628,0.935460883,0.669786337,1.308527761,0.807912718,DB0068210064355_,0.213301248,-0.066715948,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,39366,DB08889,10062355,82,3083,111,3774,0.509842366,0.904353408,0.668584452,1.219082433,0.670395527,DB0888910062355_,0.399887402,-0.100535057,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,39367,DB00480,10035484,109,67319,135,67527,0.109116794,0.809904866,0.623249496,1.050464445,0.224722631,DB0048010035484_,1.492888388,-0.210838488,NA,10035484,Plasmacytoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,39369,DB06589,10060795,33,1997,43,2610,1,1.00301564,0.614912085,1.622779302,1,DB0658910060795_,0,0.003011102,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,pazopanib,DB06589
,39370,DB00727,10007559,98,3745,102,4071,0.774733891,1.044431899,0.780475154,1.397066758,0.877224103,DB0072710007559_,0.130992785,0.0434731,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,nitroglycerin,DB00727
,39371,DB00829,10007559,32,8020,18,4436,1,0.983313382,0.534848159,1.862894552,1,DB0082910007559_,0,-0.016827408,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,diazepam,DB00829
,39372,DB00999,10007559,101,21329,89,12150,0.003108562,0.646492108,0.48088377,0.870301616,0.013929175,DB0099910007559_,4.273769729,-0.436194288,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,39374,DB00641,10035598,84,14040,76,12399,0.936707986,0.976074775,0.706411232,1.350574239,0.97678652,DB0064110035598_,0.023487156,-0.024216081,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,39375,DB00722,10035598,120,25283,128,25904,0.799068249,0.960517165,0.741998249,1.242749397,0.891461684,DB0072210035598_,0.114892822,-0.040283426,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,39377,DB00999,10035598,70,21360,59,12180,0.027907719,0.676574197,0.471285742,0.974132394,0.080021207,DB0099910035598_,2.52546359,-0.39071316,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,39387,DB01156,10028596,51,13571,38,6290,0.0298486,0.622060786,0.400268687,0.974208299,0.084385098,DB0115610028596_,2.47236446,-0.474717464,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,bupropion,DB01156
,39391,DB00471,10028334,235,13954,71,5394,0.071893751,1.279408488,0.975284654,1.696086965,0.164594228,DB0047110028334_,1.804272057,0.246397852,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,39392,DB01222,10028334,132,9142,45,5360,0.001632987,1.719768071,1.215311911,2.473380308,0.008233063,DB0122210028334_,4.799597153,0.542189439,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,budesonide,DB01222
,39403,DB00193,10006093,58,19262,20,8682,0.32903449,1.307068125,0.774001725,2.295974336,0.497640014,DB0019310006093_,0.697878326,0.267786557,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,tramadol,DB00193
,39404,DB00203,10006093,15,13863,41,8897,2.96745122101474e-07,0.234813296,0.120649949,0.433618986,4.85025086955281e-06,DB0020310006093_,12.23648013,-1.448964567,male,10006093,Bradycardia,10007541,Cardiac disorders,Card,sildenafil,DB00203
,39409,DB00635,10006093,52,33001,45,23749,0.410054277,0.831596526,0.546971166,1.268641183,0.579430512,DB0063510006093_,0.545709533,-0.1844079,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,prednisone,DB00635
,39410,DB00661,10006093,60,3468,41,1554,0.050048749,0.65580641,0.431449454,1.005432951,0.125098076,DB0066110006093_,2.07865724,-0.421889641,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,verapamil,DB00661
,39411,DB00678,10006093,68,15531,40,10684,0.492362311,1.16941653,0.779343167,1.775528766,0.655244967,DB0067810006093_,0.422746118,0.156504932,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,losartan,DB00678
,39413,DB00999,10006093,56,21374,90,12149,6.63378572280459e-10,0.353682491,0.248521933,0.499583965,1.90567276201004e-08,DB0099910006093_,17.77584564,-1.039355686,male,10006093,Bradycardia,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,39414,DB01224,10006093,63,8045,28,5889,0.03263157,1.646956552,1.038166028,2.673895941,0.090486426,DB0122410006093_,2.40255543,0.498929071,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,quetiapine,DB01224
,39415,DB00273,10021097,97,8384,28,2165,0.579034063,0.894573373,0.58054753,1.419193074,0.727772694,DB0027310021097_,0.317766513,-0.111408353,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,topiramate,DB00273
,39418,DB00697,10021097,100,5996,51,1755,0.002257867,0.57395854,0.403831406,0.824349085,0.010739783,DB0069710021097_,4.533800424,-0.555198116,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,tizanidine,DB00697
,39419,DB01224,10021097,164,7944,120,5797,1,0.997302021,0.781279736,1.27603131,1,DB0122410021097_,0,-0.002701625,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,quetiapine,DB01224
,39424,DB00635,10038435,223,32830,218,23576,0.001363133,0.734608661,0.606283657,0.890165013,0.00710841,DB0063510038435_,4.946476695,-0.308417356,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,39426,DB00678,10038435,127,15472,95,10629,0.537624069,0.918391503,0.69760435,1.21251517,0.693745088,DB0067810038435_,0.365650695,-0.085131506,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,losartan,DB00678
,39427,DB00697,10038435,35,6061,19,1787,0.034920717,0.54318031,0.301459906,1.007838729,0.095277563,DB0069710038435_,2.350960927,-0.610313952,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,tizanidine,DB00697
,39428,DB01224,10038435,36,8072,32,5885,0.460654368,0.820212723,0.494565858,1.365803732,0.627980957,DB0122410038435_,0.465245436,-0.198191554,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,quetiapine,DB01224
,39433,DB00678,10048294,64,15535,48,10676,0.700073021,0.916300448,0.619902631,1.362434146,0.819790139,DB0067810048294_,0.198706899,-0.087410968,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,losartan,DB00678
,39434,DB00697,10048294,37,6059,29,1777,0.000161073,0.374245516,0.22326148,0.632886463,0.001199042,DB0069710048294_,6.72623263,-0.982843238,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,tizanidine,DB00697
,39435,DB01104,10048294,86,15377,58,7228,0.038990138,0.696971998,0.493187204,0.991125313,0.103630698,DB0110410048294_,2.266921683,-0.361010045,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,39436,DB01224,10048294,59,8049,70,5847,0.006981499,0.612308403,0.424836906,0.879895526,0.026731055,DB0122410048294_,3.621929292,-0.490519197,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,39439,DB00060,10053762,66,9442,16,2449,0.891565971,1.069878588,0.611318776,1.983289085,0.954963795,DB0006010053762_,0.04608185,0.067545173,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,interferon beta-1a,DB00060
,39442,DB00108,10028334,108,10086,30,3265,0.55002165,1.16536218,0.769805646,1.813259735,0.704376082,DB0010810028334_,0.350442859,0.153031923,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,natalizumab,DB00108
,39443,DB08908,10028334,159,10514,39,3240,0.236972407,1.256320093,0.878184211,1.836382679,0.394316445,DB0890810028334_,0.930601532,0.228186887,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,dimethyl fumarate,DB08908
,39444,DB00060,10022067,81,9427,17,2448,0.530099002,1.237273554,0.725465242,2.231391023,0.687182318,DB0006010022067_,0.375155639,0.212910212,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,39445,DB01222,10060795,32,9242,21,5384,0.670856968,0.887717691,0.49576781,1.621528436,0.800335284,DB0122210060795_,0.222724534,-0.119101502,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,budesonide,DB01222
,39456,DB00316,10061599,97,65377,31,36922,0.005508701,1.767126955,1.168350833,2.741031765,0.02210629,DB0031610061599_,3.811893109,0.569355039,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,39458,DB00624,10019211,27,535,145,4251,0.085021675,1.479421746,0.933412612,2.268332865,0.186815543,DB0062410019211_,1.67763355,0.391651299,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,testosterone,DB00624
,39459,DB00722,10016334,80,25323,34,25998,8.17251008129281e-06,2.415716924,1.597625642,3.723588244,9.11582548214646e-05,DB0072210016334_,9.302913498,0.881996106,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,39460,DB00005,10040026,40,128042,14,42405,0.875055196,0.946225395,0.503933832,1.883124669,0.946107763,DB0000510040026_,0.055398802,-0.055274478,NA,10040026,Sensory disturbance,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,39473,DB00635,10014011,94,32959,31,23763,8.34273284133805e-05,2.186172032,1.44241518,3.397131309,0.000683355,DB0063510014011_,7.288495551,0.782152084,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,39475,DB00635,10017885,211,32842,75,23719,4.91988124909947e-08,2.031795102,1.553241375,2.682471563,9.52977734949001e-07,DB0063510017885_,13.8636743,0.708919689,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,39484,DB00635,10061603,34,33019,23,23771,0.893483257,1.06423786,0.608686969,1.892697156,0.955615536,DB0063510061603_,0.045399606,0.062258919,NA,10061603,Respiratory syncytial virus infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,39494,DB00773,10012735,73,2250,103,2724,0.355193692,0.858071007,0.623460167,1.175928251,0.52496647,DB0077310012735_,0.644420885,-0.153068425,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,etoposide,DB00773
,39495,DB01042,10012735,44,946,36,1292,0.028436504,1.668837315,1.040825111,2.69133624,0.081236115,DB0104210012735_,2.510395361,0.512127165,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,melphalan,DB01042
,39496,DB00112,10016288,74,5859,48,4043,0.78143996,1.063829922,0.728176787,1.566911978,0.880965425,DB0011210016288_,0.126736899,0.061875531,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,bevacizumab,DB00112
,39498,DB00515,10016288,115,1755,151,2000,0.279934627,0.867939075,0.669106948,1.123520696,0.443779239,DB0051510016288_,0.812428051,-0.141633756,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,cisplatin,DB00515
,39499,DB00958,10016288,189,4405,140,2445,0.013423713,0.749371683,0.59554085,0.9445977,0.045005393,DB0095810016288_,3.100972945,-0.288520179,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,carboplatin,DB00958
,39500,DB01042,10016288,37,953,69,1259,0.107797138,0.708514685,0.457665776,1.081762278,0.222746572,DB0104210016288_,1.501720604,-0.344584494,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,melphalan,DB01042
,39502,DB00515,10038435,40,1830,34,2117,0.197367115,1.360862848,0.835973073,2.226689931,0.345829919,DB0051510038435_,1.061808189,0.308118946,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,cisplatin,DB00515
,39503,DB00531,10038435,73,7179,119,6397,4.2597239713957e-05,0.546652921,0.401932255,0.739211292,0.000385229,DB0053110038435_,7.861672276,-0.603941191,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,cyclophosphamide,DB00531
,39505,DB00773,10038435,34,2289,42,2785,1,0.984940162,0.605543832,1.591675007,1,DB0077310038435_,0,-0.015174389,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,etoposide,DB00773
,39506,DB00958,10038435,39,4555,42,2543,0.003494189,0.518444806,0.325587258,0.823839409,0.01530491,DB0095810038435_,4.179581557,-0.656921706,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,carboplatin,DB00958
,39507,DB00997,10038435,55,5276,54,3460,0.038568984,0.66799394,0.449222056,0.993565195,0.10278543,DB0099710038435_,2.275111671,-0.403476177,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,doxorubicin,DB00997
,39510,DB00773,10038695,37,2286,82,2745,0.001995731,0.541881437,0.355768987,0.811777846,0.009703624,DB0077310038695_,4.635255839,-0.612708052,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etoposide,DB00773
,39511,DB00997,10038695,60,5271,74,3440,0.000337318,0.529213453,0.369015248,0.75625988,0.002223551,DB0099710038695_,6.10864985,-0.636363426,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxorubicin,DB00997
,39515,DB00531,10047216,54,7198,90,6426,0.000283674,0.535678183,0.37433586,0.760278011,0.001928456,DB0053110047216_,6.251035594,-0.624221704,NA,10047216,Venoocclusive liver disease,10019805,Hepatobiliary disorders,Hepat,cyclophosphamide,DB00531
,39530,DB00112,10061428,230,5703,142,3949,0.307246771,1.121584237,0.902192471,1.398107217,0.474374071,DB0011210061428_,0.74575909,0.114742183,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,bevacizumab,DB00112
,39533,DB00773,10061428,33,2290,52,2775,0.272071493,0.769060378,0.479807201,1.217153477,0.434960265,DB0077310061428_,0.832500597,-0.262585797,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,etoposide,DB00773
,39534,DB00958,10061428,138,4456,71,2514,0.559155601,1.096579902,0.814094372,1.487766113,0.711893873,DB0095810061428_,0.339826433,0.092196156,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,carboplatin,DB00958
,39539,DB00773,10065553,72,2251,51,2776,0.003185562,1.740814678,1.193782475,2.554695444,0.014209405,DB0077310065553_,4.253851225,0.55435321,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,etoposide,DB00773
,39540,DB00958,10065553,32,4562,33,2552,0.01868862,0.542481498,0.322151023,0.912594689,0.058573943,DB0095810065553_,2.837465347,-0.6116013,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,carboplatin,DB00958
,39546,DB00364,10013709,101,2649,57,1343,0.548399908,0.898366746,0.638392943,1.274561115,0.702829985,DB0036410013709_,0.352640258,-0.107176891,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sucralfate,DB00364
,39549,DB00188,10003239,81,7805,57,8771,0.007746243,1.596871469,1.122301345,2.285276521,0.029027414,DB0018810003239_,3.539514579,0.468046383,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,bortezomib,DB00188
,39550,DB00480,10003239,563,66865,453,67209,0.000467652,1.249214792,1.101353559,1.417531142,0.002920733,DB0048010003239_,5.835920667,0.222515187,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,39551,DB00787,10003239,222,16778,152,17096,0.000174125,1.488182494,1.203886311,1.84361959,0.001282939,DB0078710003239_,6.658601433,0.397555573,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,39552,DB00169,10006002,311,38380,74,18101,2.45499770802775e-08,1.982081931,1.532724851,2.59135341,5.05124185953107e-07,DB0016910006002_,14.49846153,0.684147773,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,39553,DB00186,10006002,115,16786,27,9981,3.09940196297566e-06,2.53248568,1.652419532,4.010409395,3.89704762481776e-05,DB0018610006002_,10.15270622,0.929201303,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,39554,DB00188,10006002,54,7832,40,8788,0.049079081,1.514734488,0.986659491,2.342852539,0.123242766,DB0018810006002_,2.093599165,0.415240168,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bortezomib,DB00188
,39555,DB00338,10006002,186,33488,72,22200,7.26837376407684e-05,1.712535094,1.297205936,2.281720958,0.000606121,DB0033810006002_,7.408431627,0.537974784,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,39556,DB00480,10006002,284,67144,199,67463,0.000102811,1.433905359,1.191650007,1.728167802,0.000817298,DB0048010006002_,7.109507017,0.360401742,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,39557,DB00722,10006002,125,25278,46,25986,4.19780580397196e-10,2.793533882,1.976451227,4.00894524,1.2457241123411e-08,DB0072210006002_,18.20096377,1.027307419,female,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,39558,DB00787,10006002,103,16897,68,17180,0.005709991,1.540046461,1.122005399,2.12550343,0.022754263,DB0078710006002_,3.783002772,0.431812585,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,39559,DB00188,10013573,203,7683,212,8616,0.485995732,1.073802424,0.879181853,1.311318168,0.649960453,DB0018810013573_,0.430843759,0.071206016,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,39567,DB00996,10020568,45,38908,12,22413,0.01843145,2.160164734,1.123523799,4.487192796,0.0579206,DB0099610020568_,2.848682178,0.770184484,NA,10020568,Hyperaesthesia,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,39568,DB00169,10022004,312,38379,84,18091,2.29164349267074e-06,1.750815264,1.370896583,2.256821206,2.98271102772223e-05,DB0016910022004_,10.42009284,0.560081545,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,39570,DB00338,10022004,183,33491,92,22180,0.030762217,1.317329501,1.019314245,1.712313045,0.086409805,DB0033810022004_,2.448654121,0.275606582,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,39571,DB00480,10022004,146,67282,135,67527,0.511520423,1.085393781,0.852774441,1.382305884,0.671845812,DB0048010022004_,0.397726411,0.081942853,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,39572,DB00722,10022004,140,25263,88,25944,0.000318648,1.633767726,1.241798407,2.159272969,0.002119617,DB0072210022004_,6.156519854,0.490888836,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,39573,DB00787,10022004,62,16938,38,17210,0.01585279,1.657744804,1.088888557,2.553427834,0.051478236,DB0078710022004_,2.966596167,0.505458127,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,39574,DB00996,10022004,236,38717,89,22336,0.000515123,1.52975797,1.1932045,1.975943068,0.003163835,DB0099610022004_,5.755970344,0.425109534,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,39576,DB08816,10000891,46,1105,73,1829,0.847247223,1.042963755,0.699480862,1.541581696,0.923422794,DB0881610000891_,0.079668085,0.042066424,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,ticagrelor,DB08816
,39578,DB08816,10062546,13,1138,39,1863,0.061007368,0.545793651,0.266145787,1.049938638,0.145309154,DB0881610062546_,1.928891713,-0.605514303,NA,10062546,Thrombosis in device,10077536,Product issues,Prod,ticagrelor,DB08816
,39579,DB00002,10013968,24,392,69,740,0.088406235,0.656822184,0.388201043,1.078291086,0.1925713,DB0000210013968_,1.647288804,-0.420341945,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetuximab,DB00002
,39581,DB01248,10016825,41,2659,10,1364,0.036095437,2.102864384,1.031924427,4.722876474,0.09771549,DB0124810016825_,2.325695182,0.743300408,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,docetaxel,DB01248
,39583,DB00002,10047700,24,392,43,766,0.790966777,1.090569683,0.623295081,1.868646031,0.886724158,DB0000210047700_,0.120221329,0.086700205,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cetuximab,DB00002
,39584,DB00002,10051792,15,401,61,748,0.005909614,0.458945178,0.239039623,0.830176561,0.023391443,DB0000210051792_,3.755384997,-0.778824514,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,cetuximab,DB00002
,39585,DB01248,10051792,46,2654,24,1350,0.89926317,0.974930675,0.580031826,1.677602618,0.956490275,DB0124810051792_,0.044484657,-0.025388913,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,docetaxel,DB01248
,39599,DB00046,10028411,35,5424,28,4664,0.801210311,1.074869653,0.634187449,1.837152154,0.892454221,DB0004610028411_,0.11378006,0.072199401,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin lispro,DB00046
,39603,DB00448,10003239,118,5027,63,3061,0.438573872,1.140512521,0.830057542,1.579563853,0.606921239,DB0044810003239_,0.499356252,0.131477741,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lansoprazole,DB00448
,39604,DB00863,10003239,324,10349,91,5749,2.38407015567853e-09,1.977793833,1.559167437,2.529567553,6.13463377797455e-08,DB0086310003239_,16.60673036,0.681981997,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,39605,DB00973,10003239,144,3707,72,2949,0.00132888,1.590936736,1.185480455,2.150784424,0.006960864,DB0097310003239_,4.967451729,0.464322985,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ezetimibe,DB00973
,39606,DB00448,10011224,122,5023,64,3060,0.359262937,1.161298534,0.848197616,1.602687496,0.529047105,DB0044810011224_,0.636677807,0.149538805,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lansoprazole,DB00448
,39607,DB00863,10011224,303,10370,139,5701,0.086373969,1.198419451,0.97450383,1.479515302,0.189003987,DB0086310011224_,1.66598717,0.181003565,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,39608,DB00973,10011224,83,3768,47,2974,0.074573259,1.39376385,0.959697524,2.044984556,0.169139538,DB0097310011224_,1.777031236,0.332007893,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ezetimibe,DB00973
,39609,DB00973,10013968,150,3701,101,2920,0.243684807,1.17171922,0.899961762,1.530664116,0.40207496,DB0097310013968_,0.911116739,0.158472089,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ezetimibe,DB00973
,39613,DB00973,10017885,33,3818,20,3001,0.405878448,1.29687313,0.720776267,2.39015914,0.57541679,DB0097310017885_,0.552660649,0.259956083,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,ezetimibe,DB00973
,39614,DB00448,10028372,33,5112,28,3096,0.188212625,0.713833051,0.417359047,1.22871238,0.334307298,DB0044810028372_,1.095694656,-0.337106166,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,lansoprazole,DB00448
,39615,DB00973,10028372,53,3798,41,2980,1,1.014268131,0.659982874,1.568595423,1,DB0097310028372_,0,0.014167299,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,ezetimibe,DB00973
,39628,DB00448,10061428,78,5067,60,3064,0.183968894,0.786142153,0.552486607,1.123267239,0.328909153,DB0044810061428_,1.111973697,-0.240617646,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,lansoprazole,DB00448
,39629,DB00863,10061428,218,10455,122,5718,0.863523783,0.977262535,0.777543512,1.232984523,0.937043613,DB0086310061428_,0.065025453,-0.022999947,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ranitidine,DB00863
,39630,DB00973,10061428,64,3787,46,2975,0.698907145,1.092999185,0.734255362,1.638116409,0.818987281,DB0097310061428_,0.199686725,0.088925464,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ezetimibe,DB00973
,39640,DB00012,10003549,101,1545,75,1238,0.639763393,1.079075024,0.784666051,1.489181968,0.776818607,DB0001210003549_,0.252548409,0.076104215,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,darbepoetin alfa,DB00012
,39641,DB00584,10003549,54,2027,61,1813,0.21968816,0.791836224,0.535548016,1.168033033,0.373078129,DB0058410003549_,0.985967419,-0.233400696,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,enalapril,DB00584
,39642,DB00736,10003549,294,10297,163,5390,0.582729022,0.944147019,0.774753596,1.153839117,0.730879054,DB0073610003549_,0.313507285,-0.057473385,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,39643,DB00887,10003549,116,2225,83,1732,0.608360734,1.087928426,0.80768005,1.470562939,0.751034851,DB0088710003549_,0.286303222,0.084275361,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,39644,DB00950,10003549,100,4618,51,2005,0.370909463,0.851349858,0.599071013,1.22259814,0.540594707,DB0095010003549_,0.615085436,-0.160932121,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,39645,DB00956,10003549,149,5665,86,3381,0.837865562,1.034028278,0.784844938,1.369346417,0.916568016,DB0095610003549_,0.087119002,0.033462124,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,39646,DB01592,10003549,224,6052,121,2946,0.380935874,0.901162559,0.715842477,1.13883142,0.550940207,DB0159210003549_,0.596128993,-0.104069617,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,39649,DB00169,10005396,69,38622,11,18164,0.00026783,2.950029168,1.55014501,6.18384911,0.001839779,DB0016910005396_,6.298109927,1.081815058,female,10005396,Blood calcium increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,39660,DB00012,10013968,106,1540,62,1251,0.045875632,1.388681561,0.996122494,1.949561291,0.117248382,DB0001210013968_,2.143460672,0.32835478,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,darbepoetin alfa,DB00012
,39661,DB00887,10013968,361,1980,185,1630,6.83061044553972e-07,1.606229085,1.325122014,1.951676974,1.02274335266882e-05,DB0088710013968_,11.49043689,0.473889249,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bumetanide,DB00887
,39662,DB01592,10013968,368,5908,161,2906,0.23374055,1.124287685,0.926521064,1.368949605,0.390496098,DB0159210013968_,0.940337302,0.117149666,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iron,DB01592
,39663,DB00820,10033425,690,11225,233,5583,3.61314625648451e-07,1.472873653,1.263199412,1.722071645,5.77334646514865e-06,DB0082010033425_,12.06225867,0.387215359,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,39672,DB09072,10001949,37,6434,25,2510,0.045949005,0.577418796,0.337597084,1.002921213,0.117404245,DB0907210001949_,2.142132211,-0.54918746,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,39676,DB00182,10010305,51,5143,28,2824,1,1.000149825,0.617288507,1.651209963,1,DB0018210010305_,0,0.000149814,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,39686,DB00182,10027175,82,5112,28,2824,0.027294718,1.617728187,1.039076713,2.587811302,0.078658226,DB0018210027175_,2.542643071,0.481022811,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,39688,DB09072,10027175,107,6364,37,2498,0.575315162,1.135107505,0.771958162,1.702450798,0.724761996,DB0907210027175_,0.32191196,0.126727364,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,39701,DB00182,10047513,46,5148,15,2837,0.081223527,1.689901192,0.924551118,3.264822203,0.180455899,DB0018210047513_,1.712268855,0.524670061,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,amphetamine,DB00182
,39717,DB01097,10016322,60,6205,7,1496,0.063398919,2.066346875,0.94104104,5.370511737,0.149638108,DB0109710016322_,1.899535514,0.725782253,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,39718,DB01097,10019211,278,5987,50,1453,0.054002661,1.349313498,0.989532063,1.872215297,0.132490636,DB0109710019211_,2.021243306,0.299595943,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,leflunomide,DB01097
,39720,DB08932,10028997,67,19376,31,6566,0.16237212,0.732412144,0.471267556,1.161339328,0.300559942,DB0893210028997_,1.20210807,-0.311411885,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,macitentan,DB08932
,39722,DB00563,10001053,32,46614,32,15316,1.4581345720239e-05,0.328583272,0.19483323,0.554129278,0.000151251,DB0056310001053_,8.796568184,-1.112964981,male,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,39734,DB00275,10012735,142,1918,81,1156,0.720851589,1.056594126,0.790414733,1.419983153,0.835410838,DB0027510012735_,0.179831654,0.055050647,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,olmesartan,DB00275
,39735,DB00973,10012735,251,3600,157,2864,0.02356185,1.2718301,1.031237206,1.572271751,0.070202134,DB0097310012735_,2.656376572,0.240456887,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ezetimibe,DB00973
,39736,DB01016,10012735,82,1019,51,1177,0.000654316,1.856630774,1.279364568,2.71596128,0.003873579,DB0101610012735_,5.553576326,0.618763433,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,glyburide,DB01016
,39756,DB09053,10033661,21,2264,51,4001,0.266529243,0.727716172,0.414645159,1.235231733,0.42870735,DB0905310033661_,0.84698076,-0.31784418,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,ibrutinib,DB09053
,39758,DB00563,10037423,56,46590,38,15310,0.000755408,0.484259664,0.315008064,0.751851149,0.004358664,DB0056310037423_,5.435589745,-0.725134021,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,39766,DB01136,10003239,198,9686,132,10983,2.68886701949848e-06,1.700795348,1.355314652,2.140004578,3.43842712758538e-05,DB0113610003239_,10.27791133,0.531095993,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,carvedilol,DB01136
,39768,DB00451,10033546,45,47226,14,15405,1,1.048524068,0.565007742,2.06897645,1,DB0045110033546_,0,0.047383526,NA,10033546,Pallor,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,39772,DB01136,10047895,211,9673,227,10888,0.663387712,1.046287597,0.861517932,1.270153654,0.794876507,DB0113610047895_,0.229568513,0.045248277,NA,10047895,Weight decreased,10022891,Investigations,Inv,carvedilol,DB01136
,39774,DB00316,10048762,75,65399,27,36926,0.049517023,1.568399599,0.997947309,2.534182544,0.124078842,DB0031610048762_,2.08683809,0.450055736,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,39778,DB00316,10062132,49,65425,19,36934,0.206031263,1.455873048,0.841503299,2.619152321,0.356496066,DB0031610062132_,1.031432075,0.375605754,NA,10062132,Tooth extraction,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,39788,DB00175,10020642,57,8074,43,6063,1,0.995417393,0.657294096,1.517313669,1,DB0017510020642_,0,-0.004593139,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,pravastatin,DB00175
,39789,DB00706,10020642,11,1064,86,15839,0.055521487,1.904025093,0.913498771,3.593665578,0.135203102,DB0070610020642_,2.000977175,0.643970115,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,tamsulosin,DB00706
,39790,DB00736,10020642,88,10503,33,5520,0.102977883,1.401476581,0.928208921,2.162254616,0.215447419,DB0073610020642_,1.535038395,0.337526381,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,esomeprazole,DB00736
,39793,DB01234,10020642,220,31405,174,32714,0.007319503,1.317057727,1.073984282,1.617250815,0.027738342,DB0123410020642_,3.584939619,0.275400254,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,39794,DB08910,10020642,70,16674,52,17436,0.069325247,1.407651535,0.968581641,2.057040689,0.160124265,DB0891010020642_,1.831805112,0.341922738,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,pomalidomide,DB08910
,39800,DB01234,10021328,29,31596,40,32848,0.278615493,0.753733656,0.450528186,1.246849351,0.442401762,DB0123410021328_,0.815536845,-0.282716215,NA,10021328,Ileus,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,39802,DB08910,10037660,270,16474,381,17107,0.000141199,0.735900163,0.626355566,0.863658165,0.001070962,DB0891010037660_,6.839197908,-0.306660817,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,39803,DB08899,10003549,6,243,503,7630,0.00999303,0.374572414,0.135434422,0.833207765,0.035548353,DB0889910003549_,3.33686144,-0.981970132,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,enzalutamide,DB08899
,39808,DB09053,10003658,110,2175,294,3758,0.000111905,0.646504149,0.511190039,0.812991299,0.000878824,DB0905310003658_,7.036926141,-0.436175664,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ibrutinib,DB09053
,39809,DB09140,10003658,106,3635,60,1738,0.312948947,0.844733618,0.60637361,1.185961099,0.480465769,DB0914010003658_,0.732999293,-0.168733946,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,oxygen,DB09140
,39810,DB09053,10013950,24,2261,35,4017,0.496381194,1.218217699,0.691397474,2.113099145,0.658576064,DB0905310013950_,0.417675254,0.197388888,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,ibrutinib,DB09053
,39814,DB09053,10038695,24,2261,84,3968,0.002300464,0.501470794,0.303668307,0.800026463,0.010898025,DB0905310038695_,4.519173723,-0.69020991,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibrutinib,DB09053
,39817,DB08908,10037844,246,10427,54,3225,0.02299453,1.408946972,1.042723854,1.933684509,0.068894475,DB0890810037844_,2.675179296,0.342842597,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dimethyl fumarate,DB08908
,39818,DB00455,10000081,166,9235,66,5052,0.031549105,1.375882939,1.026208978,1.862853474,0.088126272,DB0045510000081_,2.428984585,0.319095662,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,39823,DB01050,10000084,70,18038,9,9362,6.79803865861628e-06,4.036380907,2.00809489,9.197259779,7.74540295369436e-05,DB0105010000084_,9.465825965,1.395348475,female,10000084,Abdominal pain lower,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,39825,DB00959,10002855,177,7901,53,4949,9.62907909077877e-07,2.091748614,1.527550668,2.905818775,1.38457518545471e-05,DB0095910002855_,11.1875321,0.738000373,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,methylprednisolone,DB00959
,39826,DB14512,10002855,109,4735,26,2386,0.000413481,2.112344567,1.362530848,3.38651803,0.002632834,DB1451210002855_,5.939694462,0.7477985,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,mometasone furoate,DB14512
,39830,DB01050,10012374,71,18037,23,9348,0.049960142,1.59984534,0.98674505,2.685578965,0.124924118,DB0105010012374_,2.080048782,0.469906962,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,39832,DB00959,10012378,129,7949,42,4960,0.000179943,1.916412684,1.340668852,2.788787347,0.001318961,DB0095910012378_,6.630910979,0.650455044,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,methylprednisolone,DB00959
,39833,DB14512,10012378,69,4775,25,2387,0.186655121,1.379659384,0.859236826,2.28202699,0.332305573,DB1451210012378_,1.101700333,0.321836646,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,mometasone furoate,DB14512
,39881,DB00273,10035664,142,8339,46,2147,0.201719256,0.794801414,0.564146346,1.137811433,0.3511152,DB0027310035664_,1.046640903,-0.22966299,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,topiramate,DB00273
,39882,DB00349,10035664,41,981,37,907,1,1.02451122,0.634418194,1.659431342,1,DB0034910035664_,0,0.024215641,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,clobazam,DB00349
,39883,DB00829,10035664,198,7854,107,4347,0.903659233,1.024188048,0.802997663,1.312107885,0.957417047,DB0082910035664_,0.043516196,0.023900151,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,diazepam,DB00829
,39884,DB01068,10035664,342,13421,187,6653,0.303497006,0.906610379,0.754429865,1.092092239,0.470020257,DB0106810035664_,0.754979485,-0.098042492,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,clonazepam,DB01068
,39885,DB00455,10033425,222,9179,81,5037,0.001550685,1.503948634,1.158210643,1.969283748,0.007902239,DB0045510033425_,4.840609179,0.408094072,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,39886,DB00627,10033425,38,1291,32,1567,0.14512597,1.441175954,0.871229561,2.397610386,0.277226462,DB0062710033425_,1.282920554,0.365459415,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,niacin,DB00627
,39887,DB00956,10033425,181,5633,83,3384,0.045412768,1.310008943,1.001055837,1.726062634,0.116359567,DB0095610033425_,2.151070166,0.270033964,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocodone,DB00956
,39888,DB01076,10033425,681,25066,423,25160,8.44385532481683e-15,1.61594092,1.427386272,1.831112261,5.02710616563557e-13,DB0107610033425_,28.31876171,0.4799174,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,39890,DB01373,10033425,799,21921,114,7267,5.8251162723026e-20,2.323502185,1.903581497,2.857679688,5.96932480380015e-18,DB0137310033425_,39.65989785,0.84307561,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,39891,DB08895,10033425,1293,26821,244,6402,0.000800501,1.264867548,1.09914796,1.460294989,0.004577154,DB0889510033425_,5.386677962,0.234967412,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,39892,DB00682,10000060,248,19211,131,16233,1.23765285916673e-05,1.5996407,1.287886755,1.994380061,0.000130764,DB0068210000060_,8.942113458,0.469779042,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,39893,DB08900,10000060,50,961,15,422,0.216572528,1.463395833,0.797697663,2.838734973,0.369362114,DB0890010000060_,0.995977778,0.380759648,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,teduglutide,DB08900
,39895,DB00682,10016766,78,19381,60,16304,0.668762766,1.093639015,0.770546048,1.558827504,0.798801658,DB0068210016766_,0.224642601,0.089510682,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,39900,DB00682,10019304,82,19377,37,16327,0.001612734,1.867320627,1.251253958,2.834247585,0.008149709,DB0068210019304_,4.809773006,0.624504584,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,warfarin,DB00682
,39907,DB08900,10047899,50,961,11,426,0.033221794,2.014105942,1.022242775,4.334083771,0.091771711,DB0890010047899_,2.388451184,0.700175396,NA,10047899,Weight increased,10022891,Investigations,Inv,teduglutide,DB08900
,39909,DB00682,10050584,250,19209,160,16204,0.00702998,1.318055031,1.075283868,1.61948138,0.026881442,DB0068210050584_,3.616319127,0.276157189,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,39918,DB00060,10023232,45,9463,7,2458,0.232297714,1.669726988,0.7462455,4.394476853,0.388740397,DB0006010023232_,0.944843518,0.512660133,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,39919,DB00060,10028411,125,9383,31,2434,0.920618936,1.046004231,0.699145315,1.608408737,0.964812755,DB0006010028411_,0.035821232,0.04497741,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,39920,DB00374,10022000,260,17456,83,5641,0.949614084,1.012295719,0.786238885,1.314712719,0.98797151,DB0037410022000_,0.012101418,0.012220741,NA,10022000,Influenza,10021881,Infections and infestations,Infec,treprostinil,DB00374
,39921,DB00820,10022000,236,11679,72,5744,0.000294036,1.612046317,1.230754875,2.133355539,0.001985287,DB0082010022000_,6.221991608,0.477504376,NA,10022000,Influenza,10021881,Infections and infestations,Infec,tadalafil,DB00820
,39923,DB01240,10061024,93,5658,21,1555,0.490758126,1.217079454,0.748863326,2.065238949,0.653954391,DB0124010061024_,0.424717668,0.196454099,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,epoprostenol,DB01240
,39924,DB08908,10016322,133,10540,35,3244,0.464154468,1.169548401,0.798889174,1.753176981,0.631313568,DB0890810016322_,0.459952602,0.156617692,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,39925,DB08908,10051290,110,10563,31,3248,0.764582157,1.091080744,0.725079688,1.685603069,0.870039482,DB0890810051290_,0.139216687,0.087168713,NA,10051290,Central nervous system lesion,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,39926,DB00252,10018100,36,2196,33,1875,0.808167243,0.931476766,0.562040464,1.548201354,0.896477889,DB0025210018100_,0.10928165,-0.070984032,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,phenytoin,DB00252
,39927,DB01067,10000081,66,4295,65,4758,0.537746083,1.124827546,0.784305894,1.613652353,0.693878688,DB0106710000081_,0.365458136,0.117629731,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,glipizide,DB01067
,39929,DB01076,10013946,184,25563,104,25479,2.73197459129675e-06,1.763387045,1.378152102,2.266510371,3.48993191120104e-05,DB0107610013946_,10.26304324,0.567236417,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,39931,DB00331,10013990,62,24884,40,20712,0.232478297,1.290121581,0.852834327,1.97153623,0.388906415,DB0033110013990_,0.944416543,0.254736463,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,39932,DB00722,10013990,42,25361,76,25956,0.003041036,0.565606274,0.378302691,0.835473633,0.013668541,DB0072210013990_,4.29265833,-0.569857072,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,39934,DB01076,10013990,58,25689,53,25530,0.704233896,1.087540012,0.736036239,1.609943491,0.822683405,DB0107610013990_,0.195183837,0.083918276,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,39936,DB00331,10017533,191,24755,60,20692,1.94081245763242e-12,2.660716625,1.979924237,3.620545423,8.32140805350403e-11,DB0033110017533_,23.20960455,0.978595494,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,metformin,DB00331
,39937,DB00451,10017533,119,47152,15,15404,0.000171919,2.591815247,1.509060971,4.77751763,0.001269348,DB0045110017533_,6.669251761,0.952358498,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,39938,DB00722,10017533,60,25343,24,26008,6.55929645017348e-05,2.565647912,1.57333535,4.309152449,0.000555448,DB0072210017533_,7.495735284,0.942211044,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,lisinopril,DB00722
,39940,DB01076,10017533,50,25697,23,25560,0.002110917,2.16228162,1.294735415,3.71386048,0.010169622,DB0107610017533_,4.588350251,0.77116397,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,39941,DB08907,10017533,619,3634,200,3710,9.02921906686207e-48,3.159312686,2.671367643,3.748662592,4.94443798275978e-45,DB0890710017533_,102.0180659,1.1503545,female,10017533,Fungal infection,10021881,Infections and infestations,Infec,canagliflozin,DB08907
,39942,DB00451,10036018,132,47139,55,15364,0.126385123,0.782234626,0.566698567,1.092478635,0.250624894,DB0045110036018_,1.383797904,-0.24560055,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,39943,DB00722,10036018,63,25340,79,25953,0.240180756,0.816764389,0.576783348,1.152444661,0.398054929,DB0072210036018_,0.921165271,-0.202404611,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,39945,DB01076,10036018,60,25687,68,25515,0.479688141,0.876447548,0.608601863,1.259387058,0.644595118,DB0107610036018_,0.439132884,-0.131878419,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,39946,DB08907,10046571,316,3937,119,3791,3.48557572379309e-19,2.556806177,2.054083109,3.199213728,3.36214157430831e-17,DB0890710046571_,37.93136844,0.938758893,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,canagliflozin,DB08907
,39956,DB00480,10011985,34,67394,30,67632,0.61948711,1.137333882,0.675399202,1.924187802,0.760228331,DB0048010011985_,0.274136455,0.128686823,NA,10011985,Decubitus ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,39961,DB00297,10007515,36,1636,22,857,0.578128948,0.857251145,0.487290635,1.54008362,0.726930536,DB0029710007515_,0.318924355,-0.154024352,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,bupivacaine,DB00297
,39974,DB00555,10022086,70,6977,21,3465,0.043846341,1.655367123,1.002329447,2.843952055,0.11326597,DB0055510022086_,2.178016513,0.504022811,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,39982,DB06643,10005557,48,52373,14,7501,0.03160221,0.491048312,0.266131956,0.96492692,0.088227732,DB0664310005557_,2.427833946,-0.711212761,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,denosumab,DB06643
,39986,DB06643,10018884,84,52337,35,7480,9.53932823714566e-07,0.343016277,0.228488595,0.524847006,1.37396673592456e-05,DB0664310018884_,11.19522348,-1.069977377,male,10018884,Haemoglobin decreased,10022891,Investigations,Inv,denosumab,DB06643
,39988,DB06643,10035528,95,52326,43,7472,7.55862323786928e-09,0.315488149,0.217674806,0.463848548,1.74585599127763e-07,DB0664310035528_,15.56085068,-1.153634161,male,10035528,Platelet count decreased,10022891,Investigations,Inv,denosumab,DB06643
,39990,DB00956,10041349,84,5730,41,3426,0.307044608,1.224913912,0.83140073,1.830189454,0.47411764,DB0095610041349_,0.746299803,0.202870566,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,39993,DB00433,10003988,218,7438,121,5899,0.00188235,1.428833218,1.13579501,1.804407974,0.009263727,DB0043310003988_,4.681648818,0.35685818,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,prochlorperazine,DB00433
,39994,DB00584,10003988,55,2026,32,1842,0.050488805,1.562475809,0.987742184,2.508901467,0.125904677,DB0058410003988_,2.072230194,0.44627162,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,enalapril,DB00584
,39995,DB01118,10003988,48,3015,48,4661,0.035597266,1.545800009,1.011402498,2.362733538,0.096690518,DB0111810003988_,2.33623994,0.435541582,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,amiodarone,DB01118
,39997,DB00213,10006002,112,18783,24,13397,4.08837407342455e-09,3.328362327,2.125874956,5.4142009,1.00111544500538e-07,DB0021310006002_,16.11698083,1.202480389,female,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,39998,DB00215,10006002,42,11061,11,5265,0.078204461,1.817383202,0.918629031,3.917436003,0.175340492,DB0021510006002_,1.741025527,0.597397665,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,39999,DB00433,10006002,40,7616,31,5989,1,1.014671786,0.618168218,1.67985299,1,DB0043310006002_,0,0.014565197,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,prochlorperazine,DB00433
,40009,DB00213,10010774,392,18503,223,13198,0.007244719,1.253845366,1.059354011,1.486914433,0.027508479,DB0021310010774_,3.593260999,0.226215122,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,40010,DB00215,10010774,167,10936,64,5212,0.156006716,1.243556491,0.925030639,1.689274128,0.292172178,DB0021510010774_,1.230412,0.217975412,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,40011,DB00584,10010774,47,2034,29,1845,0.106085995,1.469949079,0.901874142,2.433003499,0.220336642,DB0058410010774_,1.512598713,0.38522776,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,enalapril,DB00584
,40012,DB01118,10010774,39,3024,52,4657,0.518270661,1.154983561,0.740486634,1.788438451,0.677563071,DB0111810010774_,0.389252637,0.144086111,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,amiodarone,DB01118
,40014,DB00215,10013971,50,11053,15,5261,0.142722896,1.586557,0.875629802,3.045034757,0.273630293,DB0021510013971_,1.29597738,0.461566259,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,40015,DB00433,10013971,34,7622,29,5991,0.79961835,0.921539831,0.544198293,1.569821384,0.891684355,DB0043310013971_,0.114643071,-0.081709278,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,40017,DB01118,10013971,28,3035,41,4668,0.901647745,1.050352218,0.624122426,1.744294797,0.957065419,DB0111810013971_,0.043883532,0.049125554,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,40025,DB00213,10016322,264,18631,110,13311,1.39114761279717e-06,1.714657931,1.366024048,2.164300777,1.92707852449927e-05,DB0021310016322_,10.85692033,0.539213604,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,40026,DB00215,10016322,176,10927,50,5226,0.00093674,1.683443699,1.221005046,2.357466949,0.005218784,DB0021510016322_,5.25549088,0.520841516,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,40027,DB00433,10016322,82,7574,45,5975,0.058929347,1.437480806,0.9857509,2.119933701,0.141444753,DB0043310016322_,1.955846074,0.362892141,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,40028,DB00584,10016322,36,2045,21,1853,0.11121217,1.553161029,0.878914427,2.811003463,0.227895212,DB0058410016322_,1.478869353,0.440292228,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,enalapril,DB00584
,40029,DB01118,10016322,29,3034,33,4676,0.242214004,1.354307414,0.791497975,2.305826993,0.400465159,DB0111810016322_,0.915128511,0.30329019,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,40031,DB00213,10017577,243,18652,100,13321,2.52266388571489e-06,1.73543841,1.367879226,2.21561177,3.24721940431028e-05,DB0021310017577_,10.3351264,0.551260067,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,40033,DB01118,10017577,27,3036,41,4668,1,1.012534036,0.597601294,1.690160351,1,DB0111810017577_,0,0.012456135,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,40034,DB00213,10018838,68,18827,51,13370,0.780364357,0.946887115,0.648478576,1.390253334,0.880415616,DB0021310018838_,0.127361192,-0.054575396,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,40036,DB00433,10018838,36,7620,18,6002,0.130932797,1.575274834,0.870424975,2.949842437,0.257092486,DB0043310018838_,1.35831939,0.454429755,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,prochlorperazine,DB00433
,40040,DB00215,10018884,87,11016,51,5225,0.235091649,0.809148313,0.565239511,1.168706174,0.392117773,DB0021510018884_,0.936193043,-0.21177305,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,citalopram,DB00215
,40041,DB00433,10018884,124,7532,88,5932,0.48597903,1.109717697,0.835790597,1.478732547,0.649960453,DB0043310018884_,0.430843759,0.104105656,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,prochlorperazine,DB00433
,40042,DB01118,10018884,68,2995,86,4623,0.243615816,1.220456898,0.871594879,1.703257425,0.40198636,DB0111810018884_,0.911337122,0.199225296,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,amiodarone,DB01118
,40056,DB01118,10028813,123,2940,135,4574,0.006444229,1.417389926,1.096023192,1.831763121,0.025062746,DB0111810028813_,3.686372776,0.3488171,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,amiodarone,DB01118
,40057,DB08901,10028813,43,464,27,553,0.012841906,1.896925189,1.125959729,3.245806819,0.043459443,DB0890110028813_,3.135927114,0.640234254,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ponatinib,DB08901
,40058,DB00213,10029366,64,18831,35,13386,0.221857251,1.299827369,0.847339705,2.023841389,0.375850193,DB0021310029366_,0.978564637,0.262231462,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,40063,DB00584,10033425,57,2024,35,1839,0.073024392,1.479565769,0.949663668,2.334202031,0.166573822,DB0058410033425_,1.79231669,0.391748646,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,enalapril,DB00584
,40064,DB01118,10033425,42,3021,39,4670,0.029220549,1.664588194,1.047958073,2.649890104,0.082975436,DB0111810033425_,2.489210663,0.509577762,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,amiodarone,DB01118
,40066,DB00433,10035528,163,7493,130,5890,0.90544107,0.985605327,0.775856188,1.254146812,0.957842738,DB0043310035528_,0.043071671,-0.014499282,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,prochlorperazine,DB00433
,40067,DB00215,10038153,39,11064,19,5257,1,0.975277605,0.549588149,1.788671457,1,DB0021510038153_,0,-0.025033126,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,citalopram,DB00215
,40068,DB00433,10038153,58,7598,33,5987,0.139448133,1.384883836,0.886878442,2.195450752,0.269066074,DB0043310038153_,1.312798302,0.325616263,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,prochlorperazine,DB00433
,40078,DB01118,10047700,62,3001,67,4642,0.045702209,1.431279761,0.993472754,2.05940218,0.116907457,DB0111810047700_,2.146372622,0.358568982,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,amiodarone,DB01118
,40080,DB00215,10050584,105,10998,29,5247,0.009064199,1.72733113,1.134030324,2.707306324,0.032919168,DB0021510050584_,3.413700168,0.546577518,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,40081,DB00433,10050584,52,7604,36,5984,0.591261652,1.136677535,0.727985075,1.792474319,0.737656337,DB0043310050584_,0.304277231,0.128109564,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,prochlorperazine,DB00433
,40084,DB00213,10051398,66,18829,102,13319,5.84400930200032e-07,0.457714131,0.330351345,0.630492723,8.8920280464879e-06,DB0021310051398_,11.63035541,-0.781510459,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pantoprazole,DB00213
,40085,DB00215,10051398,24,11079,30,5246,0.000399357,0.378830427,0.211717353,0.671037026,0.002558864,DB0021510051398_,5.968192014,-0.970666595,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,citalopram,DB00215
,40100,DB00213,10061818,210,18685,162,13259,0.427869187,0.919863529,0.744877849,1.137617169,0.596364589,DB0021310061818_,0.516903073,-0.083529958,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,40101,DB00215,10061818,82,11021,51,5225,0.136186219,0.762253927,0.530091332,1.105272493,0.264358402,DB0021510061818_,1.330449512,-0.271475541,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,40102,DB00433,10061818,258,7398,190,5830,0.498419574,1.070103437,0.880920575,1.301695436,0.660264011,DB0043310061818_,0.415115508,0.067755314,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,40104,DB01118,10061818,24,3039,33,4676,0.684957903,1.11900961,0.631515264,1.955937498,0.809706594,DB0111810061818_,0.211083327,0.112444017,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,40106,DB00433,10063743,31,7625,25,5995,1,0.974918234,0.556462411,1.724137387,1,DB0043310063743_,0,-0.025401674,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,prochlorperazine,DB00433
,40110,DB00213,10066152,93,18802,29,13392,4.47974623776643e-05,2.284087045,1.490314851,3.597756496,0.000402427,DB0021310066152_,7.817996932,0.825966402,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,pantoprazole,DB00213
,40116,DB00005,10064990,55,128027,30,42389,0.032313139,0.607008381,0.382223791,0.98129313,0.08978394,DB0000510064990_,2.41034916,-0.499212681,NA,10064990,Skin abrasion,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,40118,DB00996,10014387,98,38855,31,22394,0.003239096,1.821985311,1.20518251,2.825085517,0.014399939,DB0099610014387_,4.240531331,0.599926737,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,gabapentin,DB00996
,40119,DB01156,10014387,169,13453,68,6260,0.326497965,1.156448734,0.866300036,1.558470447,0.495009277,DB0115610014387_,0.703178774,0.145353873,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,bupropion,DB01156
,40122,DB01156,10021097,278,13344,159,6169,0.037530136,0.808337637,0.66117004,0.990908757,0.100630382,DB0115610021097_,2.296301062,-0.212775441,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,bupropion,DB01156
,40123,DB00996,10022523,84,38869,58,22367,0.295678404,0.833415239,0.589106576,1.186001067,0.461505601,DB0099610022523_,0.773261089,-0.182223275,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,40124,DB01156,10048294,121,13501,46,6282,0.277682132,1.223903236,0.863599636,1.760748583,0.441299606,DB0115610048294_,0.818031255,0.202045126,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,40133,DB04844,10013709,45,631,42,427,0.173341528,0.725261304,0.456757857,1.153499155,0.315324549,DB0484410013709_,1.154152856,-0.321223269,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tetrabenazine,DB04844
,40136,DB00864,10019744,12,6857,38,8354,0.002593612,0.384764142,0.18288354,0.752863814,0.012006534,DB0086410019744_,4.422304286,-0.95512475,NA,10019744,Hepatitis C,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,40153,DB00421,10003549,353,8550,197,5055,0.55842477,1.059410698,0.884221807,1.272164256,0.711381668,DB0042110003549_,0.340546189,0.057712809,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,40154,DB00421,10021036,73,8830,49,5203,0.510293687,0.877861116,0.601921179,1.289940899,0.670754092,DB0042110021036_,0.399352689,-0.130266881,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,spironolactone,DB00421
,40155,DB00421,10038435,121,8782,104,5148,0.005289549,0.682064638,0.519206361,0.897235733,0.02139506,DB0042110038435_,3.844595235,-0.382630848,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,spironolactone,DB00421
,40156,DB00335,10013946,71,8395,35,5430,0.195894257,1.312082109,0.862172129,2.030034095,0.344178373,DB0033510013946_,1.066595229,0.271615272,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,40157,DB01015,10013946,46,9841,25,9356,0.023868844,1.749260164,1.051596532,2.973840413,0.070923871,DB0101510013946_,2.646148219,0.559192935,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,40158,DB08934,10013946,75,4414,93,6111,0.47953371,1.116485609,0.810381778,1.533931884,0.644519395,DB0893410013946_,0.439250363,0.110185903,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,sofosbuvir,DB08934
,40172,DB00005,10002953,128,127954,12,42407,1.14220333353605e-06,3.535275494,1.955030735,7.021531466,1.61023409074792e-05,DB0000510002953_,11.0365459,1.262791229,female,10002953,Aphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,40173,DB00028,10002034,63,13395,39,5576,0.063303258,0.672458917,0.443428666,1.031143027,0.149485774,DB0002810002034_,1.900554049,-0.39681426,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,human immunoglobulin g,DB00028
,40174,DB00028,10020772,102,13356,80,5535,3.76144538616104e-05,0.528378072,0.389753473,0.718472737,0.000346243,DB0002810020772_,7.968370695,-0.637943206,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,human immunoglobulin g,DB00028
,40175,DB00073,10020772,80,7326,67,6340,0.86822992,1.033329568,0.73617508,1.454280741,0.941147842,DB0007310020772_,0.060655041,0.032786179,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,rituximab,DB00073
,40176,DB00028,10051118,91,13367,84,5531,2.52842359759858e-07,0.44827613,0.328965729,0.611467164,4.18907117950701e-06,DB0002810051118_,12.38303152,-0.802345874,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,40177,DB00073,10051118,38,7368,22,6385,0.153461791,1.496782311,0.861947692,2.66000063,0.288836288,DB0007310051118_,1.241895229,0.403317678,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,40178,DB01005,10035664,32,1063,33,834,0.310123233,0.760910657,0.448889433,1.28832478,0.477552897,DB0100510035664_,0.739080346,-0.27323933,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,hydroxyurea,DB01005
,40179,DB01261,10035664,125,3656,99,3204,0.496279127,1.106486084,0.839425957,1.461824763,0.658540367,DB0126110035664_,0.417729458,0.101189304,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sitagliptin,DB01261
,40180,DB00374,10037377,79,17637,28,5696,0.653029583,0.911194365,0.584707481,1.458440741,0.787181334,DB0037410037377_,0.239296645,-0.092999051,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,40181,DB00820,10037377,70,11845,41,5775,0.362096136,0.832421074,0.557480232,1.257237511,0.531767688,DB0082010037377_,0.631548561,-0.183416868,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,40184,DB08932,10037377,112,19331,40,6557,0.779278179,0.949747126,0.655718536,1.400673543,0.879735733,DB0893210037377_,0.12813372,-0.051559513,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,40185,DB14500,10037377,61,7748,41,4032,0.209841059,0.774281539,0.511719638,1.182175112,0.360973314,DB1450010037377_,1.018951245,-0.255819726,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,40186,DB00524,10038695,60,1517,33,1311,0.044194118,1.571041686,1.003653321,2.49722808,0.113975902,DB0052410038695_,2.171768242,0.451738894,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metolazone,DB00524
,40190,DB00820,10043607,86,11829,33,5783,0.281032426,1.273997681,0.842593144,1.967935675,0.444956016,DB0082010043607_,0.809779841,0.242159737,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,tadalafil,DB00820
,40193,DB08932,10043607,154,19289,54,6543,0.810725602,0.967372912,0.704250094,1.346358404,0.898205372,DB0893210043607_,0.107356538,-0.03317122,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,macitentan,DB08932
,40194,DB14500,10043607,101,7708,61,4012,0.360409207,0.861826819,0.619555667,1.207396997,0.530289457,DB1450010043607_,0.634332276,-0.148700935,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,potassium,DB14500
,40195,DB00005,10051059,48,128034,20,42399,0.400186214,0.794767833,0.462779598,1.413892856,0.570052547,DB0000510051059_,0.562026734,-0.229705241,NA,10051059,Oral surgery,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,40203,DB00028,10024570,43,13415,30,5585,0.038542298,0.596750266,0.365341764,0.986295041,0.102731258,DB0002810024570_,2.275638848,-0.516256568,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,human immunoglobulin g,DB00028
,40206,DB00736,10069327,52,10539,38,5515,0.120299114,0.716073195,0.461684986,1.119811556,0.241775603,DB0073610069327_,1.419745244,-0.333972889,NA,10069327,Product quality issue,10077536,Product issues,Prod,esomeprazole,DB00736
,40207,DB00043,10042682,52,6361,21,2279,0.689104817,0.887185805,0.523816655,1.554210621,0.81249806,DB0004310042682_,0.207641753,-0.119700843,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,40208,DB00043,10046735,558,5855,148,2152,0.000594209,1.385756106,1.145876275,1.683818845,0.003567564,DB0004310046735_,5.635872336,0.326245916,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,omalizumab,DB00043
,40213,DB00060,10003239,142,9366,32,2433,0.509612371,1.152712431,0.778694154,1.753515302,0.670176919,DB0006010003239_,0.400213544,0.142117801,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,40214,DB00181,10003239,224,9632,79,5792,3.26437639364033e-05,1.704978564,1.310739486,2.23717047,0.000305625,DB0018110003239_,8.093152691,0.533552538,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,40215,DB00804,10003239,87,2913,16,883,0.074780705,1.647994849,0.953785176,3.026567934,0.169499856,DB0080410003239_,1.774903204,0.499559306,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,dicyclomine,DB00804
,40216,DB00804,10003549,94,2906,31,868,0.66587648,0.905723751,0.593043477,1.417067631,0.796767144,DB0080410003549_,0.227192808,-0.09902093,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,dicyclomine,DB00804
,40218,DB00181,10006784,97,9759,27,5844,0.000249418,2.15126183,1.390114307,3.433228465,0.001731628,DB0018110006784_,6.358693498,0.766054567,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,40221,DB00472,10008531,78,10681,31,4281,1,1.008478672,0.656221371,1.584814929,1,DB0047210008531_,0,0.008442929,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,40223,DB00804,10016256,218,2782,52,847,0.134264277,1.276286872,0.929269891,1.779724773,0.261659797,DB0080410016256_,1.340710104,0.243954981,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dicyclomine,DB00804
,40224,DB00181,10025482,306,9550,132,5739,0.001572677,1.393065379,1.129088942,1.726288759,0.007991071,DB0018110025482_,4.829430487,0.331506628,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,40225,DB00472,10025482,271,10488,75,4237,0.00380026,1.459746668,1.123407968,1.916064881,0.016365241,DB0047210025482_,4.11259565,0.378262906,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,40226,DB00804,10025482,138,2862,15,884,2.16126484551914e-05,2.841241386,1.652979929,5.242666209,0.000213367,DB0080410025482_,8.452498935,1.044241064,female,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,dicyclomine,DB00804
,40231,DB00472,10028411,80,10679,33,4279,0.916831348,0.971377696,0.638925985,1.50713451,0.962974246,DB0047210028411_,0.037728611,-0.02903991,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fluoxetine,DB00472
,40247,DB00060,10022095,163,9345,35,2430,0.330624843,1.210985858,0.833734199,1.803459441,0.499343952,DB0006010022095_,0.694460138,0.191434787,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,40260,DB00620,10001367,39,4789,26,3106,0.899387378,0.972843581,0.57607712,1.668101178,0.956490275,DB0062010001367_,0.044484657,-0.027531969,NA,10001367,Adrenal insufficiency,10014698,Endocrine disorders,Endo,triamcinolone,DB00620
,40269,DB09035,10001367,48,4678,94,6596,0.071616553,0.72002283,0.496581367,1.032291048,0.164097205,DB0903510001367_,1.807296316,-0.328472359,NA,10001367,Adrenal insufficiency,10014698,Endocrine disorders,Endo,nivolumab,DB09035
,40272,DB00186,10007554,38,16863,44,9964,0.002731716,0.510305612,0.321481969,0.806680629,0.012520166,DB0018610007554_,4.380414618,-0.672745493,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,lorazepam,DB00186
,40273,DB00338,10007554,82,33592,103,22169,1.54576575334247e-05,0.525417964,0.388039946,0.709492397,0.000159054,DB0033810007554_,8.74626412,-0.643561211,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,omeprazole,DB00338
,40274,DB00425,10007554,30,12665,21,7463,0.563280616,0.841816866,0.465774695,1.548236077,0.71530937,DB0042510007554_,0.335040144,-0.172192787,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,zolpidem,DB00425
,40275,DB00451,10007554,152,47119,80,15339,0.000738652,0.618526812,0.468463715,0.821836782,0.004277476,DB0045110007554_,5.454392201,-0.480414738,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,40276,DB00497,10007554,56,19211,47,16328,1,1.012682673,0.67448115,1.526368458,1,DB0049710007554_,0,0.012602921,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,oxycodone,DB00497
,40282,DB00996,10007554,116,38837,85,22340,0.091886906,0.785030457,0.587995907,1.051667403,0.19823937,DB0099610007554_,1.618280038,-0.242032763,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,gabapentin,DB00996
,40288,DB09153,10007554,27,7772,31,5668,0.084993763,0.635218261,0.364316765,1.101170178,0.186778787,DB0915310007554_,1.677830319,-0.453786621,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,sodium chloride,DB09153
,40290,DB00697,10006784,50,6046,13,1793,0.764373106,1.14059464,0.608728865,2.294153493,0.869827189,DB0069710006784_,0.139460721,0.131549741,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,40291,DB00181,10073085,42,9814,9,5862,0.003346519,2.787281053,1.336122023,6.516873652,0.014772568,DB0018110073085_,4.214983365,1.025066588,female,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,40293,DB00996,10073085,58,38895,29,22396,0.578710843,1.151635448,0.725113598,1.866140576,0.727470804,DB0099610073085_,0.318181413,0.141183061,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,40298,DB00567,10012735,242,4277,105,1976,0.635084891,1.064807823,0.837876912,1.360512898,0.773227836,DB0056710012735_,0.257181531,0.062794335,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cephalexin,DB00567
,40299,DB00688,10012735,403,6087,266,5112,0.003074684,1.272335391,1.082159991,1.497840644,0.013809151,DB0068810012735_,4.282423796,0.240854102,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,mycophenolate mofetil,DB00688
,40301,DB00567,10028411,56,4463,12,2069,0.012382277,2.163203659,1.143078677,4.443735271,0.042205555,DB0056710028411_,3.16520342,0.771590298,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cephalexin,DB00567
,40302,DB00688,10028411,62,6428,22,5356,0.000379634,2.347974138,1.421012165,4.017256581,0.002455843,DB0068810028411_,6.009285094,0.853552888,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,mycophenolate mofetil,DB00688
,40304,DB00567,10037660,108,4411,55,2026,0.550549798,0.901929055,0.643055926,1.277337558,0.704654224,DB0056710037660_,0.350048059,-0.103219415,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,40305,DB00688,10037660,177,6313,192,5186,0.009185307,0.757324926,0.611792731,0.937009822,0.033264782,DB0068810037660_,3.403256052,-0.277962889,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,40314,DB00005,10043071,72,128010,9,42410,0.002885446,2.650529601,1.321202097,6.030979083,0.013092834,DB0000510043071_,4.335690213,0.974759469,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,etanercept,DB00005
,40316,DB00563,10003445,34,46612,47,15301,2.8922134357211e-10,0.237486372,0.148053725,0.377300772,8.79373396852853e-09,DB0056310003445_,18.54922642,-1.43764504,male,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,40320,DB00795,10003239,238,4331,54,1449,0.010109742,1.474418637,1.086059797,2.032314342,0.03588583,DB0079510003239_,3.327412776,0.388263768,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfasalazine,DB00795
,40321,DB00158,10033295,44,16771,20,8084,0.894274329,1.060446404,0.611532895,1.900529795,0.955897633,DB0015810033295_,0.04510445,0.058689956,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,40322,DB00321,10033295,91,7356,105,2745,1.285637177855e-14,0.323455137,0.240694389,0.43400714,7.43519762814492e-13,DB0032110033295_,27.92738105,-1.128694855,male,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,amitriptyline,DB00321
,40325,DB00158,10033371,815,16000,244,7860,5.31334923990486e-12,1.640825192,1.416621594,1.905829417,2.13876546356661e-10,DB0015810033371_,22.26562215,0.495199281,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,40326,DB00321,10033371,375,7072,75,2775,3.20576790690486e-08,1.961852408,1.520977716,2.558753649,6.44217197499957e-07,DB0032110033371_,14.2552299,0.673889133,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,40327,DB00795,10033371,193,4376,63,1440,1,1.008095997,0.749774492,1.370685353,1,DB0079510033371_,0,0.0080634,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,40328,DB06637,10003549,272,5890,96,1923,0.536154244,0.925044183,0.725986766,1.186781918,0.692504572,DB0663710003549_,0.367440438,-0.077913777,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,40329,DB00060,10008479,78,9430,12,2453,0.090050517,1.690737626,0.91328045,3.417355788,0.19526298,DB0006010008479_,1.633408015,0.525164899,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,40330,DB06637,10008479,50,6112,9,2010,0.097036038,1.826799636,0.887381364,4.233268812,0.206333556,DB0663710008479_,1.578261215,0.602565603,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,40331,DB06637,10013573,249,5913,63,1956,0.061059138,1.307374443,0.982945344,1.760715098,0.145404971,DB0663710013573_,1.928232528,0.268020884,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,40332,DB06637,10013968,62,6100,14,2005,0.230304334,1.455527639,0.803643494,2.821907306,0.386265278,DB0663710013968_,0.951230898,0.375368473,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dalfampridine,DB06637
,40333,DB06637,10020937,167,5995,25,1994,8.56144880613613e-05,2.221759288,1.448467444,3.542520959,0.000698983,DB0663710020937_,7.26588367,0.798299354,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,40334,DB00060,10028372,203,9305,54,2411,0.8760554,0.974054604,0.715676384,1.345193927,0.946904013,DB0006010028372_,0.05455755,-0.026287915,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,40335,DB06637,10028372,207,5955,91,1928,0.019802828,0.736498195,0.569606025,0.958318537,0.061315012,DB0663710028372_,2.791730565,-0.305848494,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,dalfampridine,DB06637
,40336,DB06637,10047513,50,6112,18,2001,0.777503276,0.909413395,0.51996823,1.660353472,0.878740499,DB0663710047513_,0.129265648,-0.094955508,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,dalfampridine,DB06637
,40342,DB00811,10028334,34,2764,36,4120,0.177560587,1.407682621,0.85224936,2.32062407,0.320724301,DB0081110028334_,1.1371734,0.341944821,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ribavirin,DB00811
,40346,DB01164,10037844,67,6457,79,7857,0.86750393,1.031995378,0.732638084,1.449963606,0.940554821,DB0116410037844_,0.061285343,0.031494189,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,calcium chloride,DB01164
,40350,DB00230,10052302,98,19576,33,8618,0.216154974,1.307306767,0.872353255,2.004737031,0.368805523,DB0023010052302_,0.997485812,0.267969118,NA,10052302,Impaired work ability,10041244,Social circumstances,SocCi,pregabalin,DB00230
,40351,DB00316,10052302,44,65430,31,36922,0.338771628,0.800953927,0.494386398,1.312231474,0.50786109,DB0031610052302_,0.677547314,-0.221951853,NA,10052302,Impaired work ability,10041244,Social circumstances,SocCi,acetaminophen,DB00316
,40359,DB00480,10003119,63,67365,107,67555,0.000914715,0.590451553,0.425365647,0.813670122,0.005120493,DB0048010003119_,5.274504536,-0.526867691,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,40361,DB00993,10033371,115,3134,29,1590,0.000594868,2.011606963,1.322167987,3.150753833,0.003571107,DB0099310033371_,5.634879523,0.698933886,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,azathioprine,DB00993
,40364,DB01068,10003988,267,13496,72,6768,1.22317093369284e-06,1.859611611,1.426007959,2.451630803,1.71335187807707e-05,DB0106810003988_,10.97447385,0.620367655,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,40366,DB00704,10019211,271,4085,273,4921,0.046028797,1.195799659,1.00181392,1.427347713,0.117536983,DB0070410019211_,2.141002246,0.178815132,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,naltrexone,DB00704
,40367,DB00246,10001497,19,1055,39,662,1.61129960547619e-05,0.305908297,0.165471965,0.547658424,0.000164862,DB0024610001497_,8.710402687,-1.184469906,male,10001497,Agitation,10037175,Psychiatric disorders,Psych,ziprasidone,DB00246
,40371,DB00246,10029282,31,1043,43,658,0.000991751,0.455019348,0.274138075,0.747466366,0.005465399,DB0024610029282_,5.209318095,-0.787415338,NA,10029282,Neuroleptic malignant syndrome,10029205,Nervous system disorders,Nerv,ziprasidone,DB00246
,40375,DB00246,10044565,37,1037,18,683,0.328893503,1.353628084,0.744259677,2.547745101,0.497509034,DB0024610044565_,0.698141563,0.302788458,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,ziprasidone,DB00246
,40384,DB00531,10020751,41,7211,14,6502,0.001049281,2.640313726,1.408464788,5.248812729,0.00573631,DB0053110020751_,5.160939116,0.970897746,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,cyclophosphamide,DB00531
,40385,DB00959,10020751,128,7950,48,4954,0.002287632,1.66165721,1.181332302,2.37089998,0.010855824,DB0095910020751_,4.523053569,0.507815424,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,methylprednisolone,DB00959
,40423,DB00203,10024670,58,13820,27,8911,0.18186679,1.385085438,0.862439741,2.27690762,0.326249349,DB0020310024670_,1.120093317,0.325761826,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,sildenafil,DB00203
,40424,DB00338,10024670,59,33615,41,22231,0.838236881,0.9517074,0.627934886,1.454707293,0.916840664,DB0033810024670_,0.086821579,-0.049497645,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,omeprazole,DB00338
,40426,DB00451,10024670,76,47195,24,15395,1,1.032981179,0.645152634,1.710387882,1,DB0045110024670_,0,0.03244897,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,levothyroxine,DB00451
,40432,DB00682,10024670,43,19416,15,16349,0.002266521,2.41371533,1.314040616,4.678840769,0.010772173,DB0068210024670_,4.530789045,0.881167191,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,warfarin,DB00682
,40433,DB00695,10024670,61,27988,38,20490,0.47656824,1.175190005,0.770878493,1.812135368,0.641978023,DB0069510024670_,0.443201207,0.161429841,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,furosemide,DB00695
,40443,DB08932,10024670,80,19363,26,6571,0.911229559,1.044209187,0.662836563,1.695465492,0.960120631,DB0893210024670_,0.040696345,0.04325984,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,macitentan,DB08932
,40446,DB00007,10035664,11,1936,76,4376,0.000142345,0.3272052,0.156386785,0.620860922,0.001078564,DB0000710035664_,6.832124682,-1.117167782,male,10035664,Pneumonia,10021881,Infections and infestations,Infec,leuprolide,DB00007
,40447,DB00047,10035664,267,9018,272,8246,0.220469151,0.897590736,0.753224648,1.069526516,0.37402986,DB0004710035664_,0.983419644,-0.108041065,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,40448,DB00165,10035664,71,2074,58,1308,0.167445613,0.772092075,0.534106169,1.119894877,0.307465016,DB0016510035664_,1.179393968,-0.258651469,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pyridoxine,DB00165
,40449,DB00175,10035664,303,7828,266,5840,0.06298069,0.84982509,0.715811491,1.009361404,0.148918045,DB0017510035664_,1.90435916,-0.162724727,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pravastatin,DB00175
,40450,DB00572,10035664,121,2781,95,2031,0.622505253,0.93020182,0.700641907,1.237888984,0.762680645,DB0057210035664_,0.270915887,-0.072353706,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,atropine,DB00572
,40452,DB00843,10035664,63,2131,77,2096,0.229173117,0.804785651,0.564263691,1.14424372,0.384896035,DB0084310035664_,0.954782021,-0.217179309,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,donepezil,DB00843
,40453,DB01062,10035664,159,4327,74,1671,0.206083996,0.829815447,0.622048226,1.115283598,0.3565459,DB0106210035664_,1.031292295,-0.186551956,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,oxybutynin,DB01062
,40454,DB01306,10035664,159,4049,168,3698,0.213773268,0.864401273,0.688186651,1.085366902,0.365953326,DB0130610035664_,1.005249479,-0.145718182,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,insulin aspart,DB01306
,40460,DB00203,10035759,37,13841,27,8911,0.610905476,0.882268179,0.522454768,1.50781737,0.752978848,DB0020310035759_,0.283718141,-0.125259211,NA,10035759,Pneumothorax,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,40463,DB00451,10035759,34,47237,20,15399,0.039650022,0.554205573,0.309869218,1.016393776,0.104960051,DB0045110035759_,2.254175472,-0.590219591,NA,10035759,Pneumothorax,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,40470,DB00695,10035759,38,28011,28,20500,1,0.993231665,0.593471705,1.680827246,1,DB0069510035759_,0,-0.006791344,NA,10035759,Pneumothorax,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,40480,DB08932,10035759,53,19390,19,6578,0.787942086,0.946318324,0.55059605,1.6940216,0.88510685,DB0893210035759_,0.122046907,-0.055176272,NA,10035759,Pneumothorax,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,40513,DB00695,10025127,34,28015,21,20507,0.586737798,1.185125657,0.668095668,2.149580807,0.733875946,DB0069510025127_,0.309415275,0.169848808,NA,10025127,Lung transplant,10042613,Surgical and medical procedures,Surg,furosemide,DB00695
,40518,DB00695,10061026,38,28011,40,20488,0.109558578,0.694872256,0.433619667,1.111773824,0.225420525,DB0069510061026_,1.48978762,-0.364027255,NA,10061026,Cardiac operation,10042613,Surgical and medical procedures,Surg,furosemide,DB00695
,40520,DB08932,10061026,83,19360,30,6567,0.745874665,0.938462739,0.610764414,1.477786319,0.854980527,DB0893210061026_,0.156676586,-0.063512126,NA,10061026,Cardiac operation,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,40523,DB00264,10002424,72,29535,66,24826,0.60913739,0.916978645,0.647131586,1.301194168,0.751674676,DB0026410002424_,0.28545166,-0.086671095,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,40528,DB01076,10002424,64,25683,65,25518,0.929890032,0.978286602,0.681460406,1.403991572,0.971237364,DB0107610002424_,0.029184387,-0.021952602,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,40533,DB00203,10020642,96,13782,41,8897,0.027982257,1.511509839,1.037153256,2.237812248,0.080186823,DB0020310020642_,2.523396076,0.413109045,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,sildenafil,DB00203
,40534,DB00285,10020642,141,10810,57,3661,0.284671001,0.837738184,0.610260397,1.163283,0.4492193,DB0028510020642_,0.800244092,-0.177049657,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,venlafaxine,DB00285
,40535,DB00338,10020642,282,33392,150,22122,0.029998292,1.245471173,1.01731253,1.529775107,0.084698976,DB0033810020642_,2.468651771,0.219513911,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,40536,DB00425,10020642,111,12584,62,7422,0.752592657,1.055928162,0.765955947,1.467016123,0.860624775,DB0042510020642_,0.150096671,0.054420155,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,zolpidem,DB00425
,40540,DB00999,10020642,167,21263,93,12146,0.897049895,1.025751977,0.790452338,1.337836808,0.956338178,DB0099910020642_,0.044643686,0.02542598,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,40541,DB01076,10020642,174,25573,155,25428,0.347099102,1.116212718,0.893100981,1.396117937,0.516524538,DB0107610020642_,0.660632484,0.109941454,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,40542,DB13867,10020642,35,4515,19,2535,1,1.034268502,0.574279182,1.918283364,1,DB1386710020642_,0,0.033694415,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone,DB13867
,40544,DB00264,10033546,23,29584,32,24860,0.077529862,0.603992571,0.337395415,1.065243723,0.174177131,DB0026410033546_,1.747682505,-0.504193381,NA,10033546,Pallor,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,40565,DB00264,10042727,62,29545,37,24855,0.10629476,1.409665906,0.923105014,2.17986268,0.220630772,DB0026410042727_,1.511264692,0.34335273,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,40570,DB00999,10042727,67,21363,32,12207,0.464137899,1.19634787,0.77356282,1.885503831,0.631313568,DB0099910042727_,0.459952602,0.179273475,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,40571,DB01076,10042727,54,25693,24,25559,0.000897205,2.238375034,1.359649919,3.787227613,0.005038573,DB0107610042727_,5.290632358,0.805750171,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,40584,DB00390,10013700,56,4089,24,3277,0.009224922,1.869808842,1.137226825,3.161530787,0.033370845,DB0039010013700_,3.400072663,0.625836202,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,digoxin,DB00390
,40597,DB01202,10035669,26,6688,44,5674,0.005389757,0.501351754,0.295955959,0.833612431,0.021713506,DB0120210035669_,3.829820832,-0.69044732,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,levetiracetam,DB01202
,40600,DB01080,10041962,32,2027,30,2082,0.79831567,1.095573882,0.642111087,1.874022485,0.891009846,DB0108010041962_,0.115399801,0.091278319,NA,10041962,Status epilepticus,10029205,Nervous system disorders,Nerv,vigabatrin,DB01080
,40606,DB00374,10042609,38,17678,16,5708,0.427070389,0.766866502,0.417158297,1.474310986,0.595703791,DB0037410042609_,0.518011731,-0.265442545,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,treprostinil,DB00374
,40607,DB00820,10042609,52,11863,21,5795,0.532849426,1.20956819,0.715270227,2.116257404,0.689634254,DB0082010042609_,0.371593889,0.190263428,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,tadalafil,DB00820
,40611,DB14726,10018884,28,1989,53,2795,0.213124941,0.742429688,0.450445802,1.200002241,0.365176433,DB1472610018884_,1.007374664,-0.297827109,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,dabigatran,DB14726
,40612,DB14726,10021097,54,1963,54,2794,0.075390953,1.423199765,0.953188161,2.12502688,0.170471952,DB1472610021097_,1.7691845,0.352907692,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,dabigatran,DB14726
,40617,DB01273,10019211,77,1963,26,1249,0.005258414,1.884006799,1.186325533,3.080491148,0.021292061,DB0127310019211_,3.849421017,0.633400785,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,varenicline,DB01273
,40618,DB01273,10022437,79,1961,39,1236,0.247727098,1.276645343,0.85315615,1.93795172,0.407032771,DB0127310022437_,0.898861578,0.244235812,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,varenicline,DB01273
,40629,DB08908,10021789,73,10600,26,3253,0.551743607,0.861679465,0.54291636,1.407486539,0.705653012,DB0890810021789_,0.348631646,-0.148871928,NA,10021789,Infection,10021881,Infections and infestations,Infec,dimethyl fumarate,DB08908
,40631,DB00537,10033557,57,7500,16,4282,0.010102432,2.033839823,1.150137982,3.799433608,0.03586957,DB0053710033557_,3.327865978,0.709925545,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,ciprofloxacin,DB00537
,40632,DB00537,10042674,56,7501,12,4286,0.000936204,2.666293868,1.410713119,5.471151139,0.005216351,DB0053710042674_,5.255957219,0.980689444,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,40636,DB00982,10060933,55,3309,35,2066,0.91355719,0.981129579,0.628298363,1.55035901,0.961302297,DB0098210060933_,0.039466354,-0.019050739,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,isotretinoin,DB00982
,40642,DB00374,10003119,47,17669,18,5706,0.563046962,0.84320622,0.480114061,1.544043863,0.715116301,DB0037410003119_,0.335310091,-0.170543725,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,treprostinil,DB00374
,40643,DB00682,10003119,71,19388,36,16328,0.014737913,1.660919935,1.096559228,2.55547571,0.048636037,DB0068210003119_,3.023390518,0.507371626,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,warfarin,DB00682
,40644,DB00203,10033557,463,13415,104,8834,3.08562803715329e-27,2.931509885,2.360821212,3.668746615,5.61285349180445e-25,DB0020310033557_,55.83956809,1.075517609,female,10033557,Palpitations,10007541,Cardiac disorders,Card,sildenafil,DB00203
,40645,DB00374,10033557,533,17183,83,5641,1.46272393367625e-11,2.108210148,1.666559498,2.695193916,5.42280657216929e-10,DB0037410033557_,21.33523743,0.745839316,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,treprostinil,DB00374
,40646,DB01104,10039020,36,15427,26,7260,0.102253343,0.651609437,0.382334539,1.124820653,0.21434956,DB0110410039020_,1.54014714,-0.42830992,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,40647,DB00515,10005483,23,1847,47,2104,0.02166745,0.557533346,0.321774371,0.940919727,0.065875764,DB0051510005483_,2.719984675,-0.584232964,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,cisplatin,DB00515
,40648,DB08880,10011906,46,3292,18,791,0.081893795,0.614131654,0.347025421,1.131803982,0.181537288,DB0888010011906_,1.706294205,-0.487545954,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,teriflunomide,DB08880
,40652,DB00341,10046735,269,11136,100,4968,0.137879411,1.20003518,0.94800092,1.529064128,0.266756978,DB0034110046735_,1.321417229,0.182350873,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,cetirizine,DB00341
,40653,DB00471,10046735,286,13903,66,5399,9.00193423141287e-05,1.68276266,1.280965701,2.238215863,0.00072977,DB0047110046735_,7.2227806,0.520436883,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,40654,DB00950,10046735,95,4623,33,2023,0.286117553,1.259671955,0.836432631,1.939947048,0.45083475,DB0095010046735_,0.796654415,0.230851334,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,fexofenadine,DB00950
,40656,DB00480,10061623,1222,66206,1211,66451,0.758972396,1.012818784,0.933992397,1.098306157,0.865568244,DB0048010061623_,0.144369058,0.012737319,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,40658,DB00684,10021789,94,2698,86,2262,0.594210501,0.91640546,0.672909176,1.249356374,0.740162623,DB0068410021789_,0.300885356,-0.087296371,NA,10021789,Infection,10021881,Infections and infestations,Infec,tobramycin,DB00684
,40660,DB00425,10007739,41,12654,22,7462,0.7945552,1.098985111,0.638967767,1.938786218,0.888756263,DB0042510007739_,0.117932251,0.094387128,NA,10007739,Cataract,10015919,Eye disorders,Eye,zolpidem,DB00425
,40663,DB00695,10007739,125,27924,69,20459,0.068400094,1.327287145,0.980914496,1.80870404,0.158391019,DB0069510007739_,1.842688498,0.283137118,NA,10007739,Cataract,10015919,Eye disorders,Eye,furosemide,DB00695
,40666,DB01234,10007739,253,31372,198,32690,0.002866509,1.331448528,1.100379802,1.612842605,0.013030284,DB0123410007739_,4.340479063,0.286267468,NA,10007739,Cataract,10015919,Eye disorders,Eye,dexamethasone,DB01234
,40667,DB08910,10007739,90,16654,70,17418,0.068210128,1.344678917,0.972254673,1.866224807,0.158069491,DB0891010007739_,1.844720525,0.296155261,NA,10007739,Cataract,10015919,Eye disorders,Eye,pomalidomide,DB08910
,40678,DB01048,10028813,29,436,71,1064,1,0.996771615,0.614645291,1.580750488,1,DB0104810028813_,0,-0.003233608,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,abacavir,DB01048
,40685,DB06684,10010144,35,712,22,313,0.238377972,0.699609062,0.39175545,1.273866709,0.396028504,DB0668410010144_,0.926269089,-0.357233583,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,vilazodone,DB06684
,40689,DB08896,10013952,86,737,115,925,0.707227436,0.93860126,0.689481103,1.274178485,0.824952213,DB0889610013952_,0.192429818,-0.063364533,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,regorafenib,DB08896
,40691,DB08896,10028813,117,706,100,940,0.002249352,1.557380902,1.160746353,2.092640174,0.010703155,DB0889610028813_,4.537216689,0.443005501,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,regorafenib,DB08896
,40692,DB08896,10033371,54,769,72,968,0.78114877,0.944098598,0.642252169,1.381043813,0.880828655,DB0889610033371_,0.126892162,-0.057524671,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,regorafenib,DB08896
,40694,DB08896,10047895,83,740,88,952,0.257948855,1.213257846,0.873867048,1.683340043,0.418853168,DB0889610047895_,0.870234856,0.193309176,NA,10047895,Weight decreased,10022891,Investigations,Inv,regorafenib,DB08896
,40695,DB08896,10061428,112,711,125,915,0.327173649,1.152988645,0.86857368,1.529196111,0.495577673,DB0889610061428_,0.702031181,0.142357393,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,regorafenib,DB08896
,40697,DB14726,10000081,30,1987,38,2810,0.710372611,1.116440338,0.66553953,1.8574178,0.827231264,DB1472610000081_,0.189670981,0.110145354,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,dabigatran,DB14726
,40698,DB00005,10061818,45,128037,31,42388,0.002140167,0.480559168,0.297468048,0.785678775,0.010282269,DB0000510061818_,4.577334325,-0.73280492,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,40702,DB09033,10000081,61,2563,39,1630,1,0.994728371,0.65142578,1.534828903,1,DB0903310000081_,0,-0.005285573,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,vedolizumab,DB09033
,40723,DB01276,10033645,93,1924,84,1427,0.212738025,0.821201046,0.599729866,1.125778629,0.364703668,DB0127610033645_,1.008670122,-0.196987321,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,exenatide,DB01276
,40741,DB00682,10023424,65,19394,16,16348,1.60980787896169e-06,3.424231539,1.957886018,6.343703194,2.19356143589984e-05,DB0068210023424_,10.72739902,1.230877078,female,10023424,Kidney infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,40745,DB14512,10003553,152,4692,52,2360,0.019197725,1.47018725,1.061939968,2.063474785,0.059862649,DB1451210003553_,2.815702529,0.385389774,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mometasone furoate,DB14512
,40748,DB08896,10047700,83,740,64,976,0.002359448,1.709936346,1.201446904,2.442976061,0.011131308,DB0889610047700_,4.497993583,0.536456145,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,regorafenib,DB08896
,40749,DB00264,10013950,179,29428,114,24778,0.021697035,1.322059009,1.038863786,1.688154474,0.065942829,DB0026410013950_,2.718967134,0.279190377,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,40750,DB06285,10011906,176,8674,56,1050,1.53473009375544e-08,0.380499095,0.278110575,0.527291529,3.3011768015026e-07,DB0628510011906_,14.92381664,-0.96627148,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,40751,DB01050,10013836,23,18085,36,9335,2.57495538168712e-05,0.329791796,0.186460558,0.572317164,0.00024774,DB0105010013836_,8.303128766,-1.109293745,male,10013836,Duodenal ulcer,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,40752,DB01050,10017788,14,18094,93,9278,1.0497939024762e-29,0.07718969,0.040601067,0.13625128,2.28048204351957e-27,DB0105010017788_,61.34541067,-2.561489378,male,10017788,Gastric haemorrhage,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,40758,DB00999,10000496,37,21393,18,12221,0.674342266,1.174231006,0.651487927,2.192033765,0.802491104,DB0099910000496_,0.22003451,0.160613471,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,40781,DB00005,10024570,95,127987,30,42389,0.917600331,1.048759936,0.689148681,1.63863396,0.963386915,DB0000510024570_,0.037300167,0.047608453,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,40782,DB00005,10067621,47,128035,11,42408,0.362624054,1.415193399,0.723348468,3.026214879,0.53220767,DB0000510067621_,0.630721509,0.347266199,NA,10067621,Oral disorder,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,40788,DB00531,10007882,58,7194,45,6471,0.488935554,1.15934199,0.770719946,1.753814128,0.652402205,DB0053110007882_,0.427094028,0.147852594,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,40789,DB00541,10007882,36,3098,30,4267,0.045213411,1.652657433,0.987313573,2.784710078,0.115990094,DB0054110007882_,2.154250488,0.502384558,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,vincristine,DB00541
,40790,DB00997,10007882,43,5288,19,3495,0.153557626,1.495724118,0.851514913,2.722510356,0.288913223,DB0099710007882_,1.241628901,0.402610449,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,doxorubicin,DB00997
,40791,DB00073,10021789,149,7257,84,6323,0.001439104,1.545461945,1.172325723,2.048710351,0.007430141,DB0007310021789_,4.902210479,0.435322859,NA,10021789,Infection,10021881,Infections and infestations,Infec,rituximab,DB00073
,40792,DB00541,10021789,54,3080,75,4222,1,0.986962202,0.680229216,1.423800797,1,DB0054110021789_,0,-0.013123536,NA,10021789,Infection,10021881,Infections and infestations,Infec,vincristine,DB00541
,40793,DB00635,10021789,473,32580,279,23515,0.008209761,1.223627262,1.052058403,1.425293599,0.030421312,DB0063510021789_,3.492611868,0.201819613,NA,10021789,Infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,40799,DB01076,10005470,47,25700,103,25480,3.70054050576717e-06,0.452413437,0.313197812,0.645086048,4.5389037421414e-05,DB0107610005470_,10.00023995,-0.793158833,NA,10005470,Blood creatine phosphokinase increased,10022891,Investigations,Inv,atorvastatin,DB01076
,40809,DB00005,10003658,166,127916,86,42333,0.000996401,0.63880057,0.489344503,0.838973316,0.00548375,DB0000510003658_,5.205966084,-0.448162971,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,etanercept,DB00005
,40810,DB00051,10013786,104,25627,35,11385,0.167583334,1.320026486,0.891600863,1.997070274,0.30766041,DB0005110013786_,1.178758669,0.277651802,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,40811,DB00005,10019304,45,128037,12,42407,0.645539273,1.242024752,0.646087161,2.579849788,0.781233444,DB0000510019304_,0.24688127,0.216742912,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,etanercept,DB00005
,40813,DB00051,10020772,216,25515,57,11363,0.000282932,1.687605054,1.254013032,2.303118856,0.00192565,DB0005110020772_,6.252491934,0.523310396,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,adalimumab,DB00051
,40819,DB00343,10038435,102,8634,57,5038,0.868710242,1.044170375,0.746364834,1.473323798,0.941532604,DB0034310038435_,0.060246302,0.043222671,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,diltiazem,DB00343
,40820,DB00433,10038435,73,7583,63,5957,0.603174576,0.910274054,0.639693396,1.298413196,0.746917473,DB0043310038435_,0.291800578,-0.094009567,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,prochlorperazine,DB00433
,40821,DB00727,10038435,41,3802,45,4128,1,0.989234343,0.630260399,1.548751325,1,DB0072710038435_,0,-0.010824026,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,nitroglycerin,DB00727
,40822,DB00904,10038435,195,22874,151,14305,0.052087595,0.807626941,0.648982983,1.006577992,0.128958354,DB0090410038435_,2.048265766,-0.213655034,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,ondansetron,DB00904
,40823,DB01136,10038435,145,9739,181,10934,0.371010544,0.899422311,0.716584573,1.1272522,0.540667081,DB0113610038435_,0.614951566,-0.106002598,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,carvedilol,DB01136
,40833,DB01234,10003662,23,31602,69,32819,3.0152523020686e-06,0.346146326,0.205950892,0.562157548,3.80671982516201e-05,DB0123410003662_,10.17615758,-1.060893686,male,10003662,Atrial flutter,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,40851,DB00390,10034474,35,4110,17,3284,0.094449894,1.644946426,0.895289789,3.137137808,0.202431136,DB0039010034474_,1.597355518,0.497707816,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,digoxin,DB00390
,40853,DB01234,10034474,52,31573,44,32844,0.357974334,1.229386823,0.806725544,1.881098433,0.527701041,DB0123410034474_,0.639225366,0.206515527,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,40890,DB00586,10003246,90,7019,18,2787,0.006907112,1.985209217,1.184911568,3.507440878,0.0265177,DB0058610003246_,3.629942851,0.685724308,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,40891,DB01050,10003246,88,18020,33,9338,0.124155599,1.381856544,0.915782835,2.130782671,0.247299394,DB0105010003246_,1.397155557,0.323427916,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,40892,DB01050,10011469,48,18060,16,9355,0.146318087,1.553963432,0.866473687,2.933389507,0.278800402,DB0105010011469_,1.277259159,0.44080872,NA,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,40896,DB01050,10022086,224,17884,69,9302,9.05469421647832e-05,1.688507229,1.282164339,2.247721881,0.000733218,DB0105010022086_,7.218067179,0.523844842,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,40897,DB00586,10028391,63,7046,14,2791,0.055907131,1.782420713,0.985862718,3.450406461,0.135921166,DB0058610028391_,1.995680226,0.577972391,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,40898,DB01050,10028391,121,17987,46,9325,0.085181146,1.363686804,0.962625317,1.961062896,0.18707327,DB0105010028391_,1.676254919,0.310191917,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,40899,DB00586,10033371,428,6681,125,2680,0.002177822,1.373498907,1.116795011,1.698669674,0.010434572,DB0058610033371_,4.562630785,0.31736143,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,40900,DB00563,10040984,113,46533,27,15321,0.142064014,1.377946187,0.898641703,2.182897393,0.272685307,DB0056310040984_,1.29943687,0.32059412,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,40902,DB01050,10040984,67,18041,38,9333,0.6802133,0.91212517,0.603230597,1.397257381,0.806591008,DB0105010040984_,0.214938544,-0.091978051,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,40903,DB00563,10044755,50,46596,19,15329,0.578250106,0.865751749,0.501297248,1.555490083,0.727030711,DB0056310044755_,0.318786559,-0.144157076,NA,10044755,Tuberculosis,10021881,Infections and infestations,Infec,methotrexate,DB00563
,40907,DB01050,10048334,72,18036,34,9337,0.758222252,1.096271021,0.718904132,1.70178017,0.86499303,DB0105010048334_,0.14503383,0.09191444,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,40909,DB01050,10061218,47,18061,13,9358,0.041489497,1.873211213,0.996431912,3.775550433,0.108728957,DB0105010061218_,2.218897127,0.627654184,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,40914,DB00811,10010305,35,2763,38,4118,0.187878453,1.372655829,0.839674307,2.238134699,0.333940987,DB0081110010305_,1.096790987,0.316747425,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ribavirin,DB00811
,40920,DB00310,10028813,55,889,29,752,0.043604804,1.603851218,0.993469463,2.637481252,0.11282692,DB0031010028813_,2.181900317,0.472407749,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,chlorthalidone,DB00310
,40923,DB00213,10005555,45,18850,15,13406,0.008669114,2.133520349,1.166736967,4.122517447,0.031767416,DB0021310005555_,3.449314183,0.757773361,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,40925,DB00381,10005555,102,29258,68,22819,0.352930268,1.169873999,0.851949236,1.615059008,0.522693942,DB0038110005555_,0.648759183,0.15689605,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,amlodipine,DB00381
,40930,DB00193,10048865,58,19262,18,8684,0.174293263,1.452701511,0.843160569,2.621581363,0.316533282,DB0019310048865_,1.150326887,0.373424934,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,tramadol,DB00193
,40932,DB00381,10048865,97,29263,59,22828,0.145721641,1.282526479,0.918088734,1.804890236,0.278071316,DB0038110048865_,1.279877666,0.248831944,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,amlodipine,DB00381
,40933,DB00480,10048865,155,67273,180,67482,0.189364277,0.863788012,0.692137795,1.077053025,0.335735052,DB0048010048865_,1.091432967,-0.146427897,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,lenalidomide,DB00480
,40934,DB00736,10048865,39,10552,13,5540,0.187962651,1.575015706,0.822178748,3.218538346,0.334005954,DB0073610048865_,1.09659646,0.454265244,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,esomeprazole,DB00736
,40935,DB01234,10048865,73,31552,77,32811,0.935070607,0.985880331,0.705559645,1.376484087,0.975328369,DB0123410048865_,0.024981076,-0.0142203,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,dexamethasone,DB01234
,40936,DB00503,10036590,38,675,13,1000,1.64563405204477e-06,4.326882473,2.234302295,8.923971487,2.23716012712681e-05,DB0050310036590_,10.7077182,1.4648473,female,10036590,Premature baby,10036585,"Pregnancy, puerperium and perinatal conditions",Preg,ritonavir,DB00503
,40938,DB00879,10036590,35,1742,15,3697,5.2087482076941e-08,4.950140402,2.626005463,9.783598945,1.00375327448123e-06,DB0087910036590_,13.81176431,1.59941594,female,10036590,Premature baby,10036585,"Pregnancy, puerperium and perinatal conditions",Preg,emtricitabine,DB00879
,40946,DB00503,10071404,113,600,96,917,9.08739823391117e-05,1.798284718,1.330852384,2.433974185,0.000735187,DB0050310071404_,7.215385643,0.586833276,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,ritonavir,DB00503
,40948,DB00879,10071404,154,1623,131,3581,1.00826782683398e-14,2.593299397,2.02537275,3.324298184,5.9289306103649e-13,DB0087910071404_,28.15376235,0.952930964,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,emtricitabine,DB00879
,40950,DB01264,10071404,48,342,36,715,1.17538903927157e-05,2.784785029,1.734035367,4.506448469,0.000125056,DB0126410071404_,8.9867484,1.024170681,female,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,darunavir,DB01264
,40954,DB01098,10001760,132,8017,16,7193,3.96048340668288e-21,7.401299823,4.386780757,13.33754281,4.66822001545558e-19,DB0109810001760_,42.20833892,2.001655637,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,rosuvastatin,DB01098
,40955,DB00316,10021576,51,65423,24,36929,0.547794811,1.199454176,0.724743633,2.038051245,0.702363754,DB0031610021576_,0.353303841,0.1818666,NA,10021576,Inadequate analgesia,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,40956,DB00497,10021576,91,19176,92,16283,0.264649348,0.839910783,0.621156857,1.135548023,0.426610334,DB0049710021576_,0.85188425,-0.174459603,NA,10021576,Inadequate analgesia,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,40957,DB00497,10047340,36,19231,32,16343,0.903298386,0.956035203,0.576940647,1.590804901,0.957348417,DB0049710047340_,0.043587882,-0.044960543,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,oxycodone,DB00497
,40964,DB00451,10069889,59,47212,8,15411,0.015146407,2.407448014,1.144995005,5.835683142,0.04969708,DB0045110069889_,3.001809102,0.878567271,NA,10069889,Product adhesion issue,10077536,Product issues,Prod,levothyroxine,DB00451
,40965,DB00996,10069889,43,38910,9,22416,0.003583712,2.752422196,1.323090827,6.422671164,0.015613771,DB0099610069889_,4.159601995,1.012481322,female,10069889,Product adhesion issue,10077536,Product issues,Prod,gabapentin,DB00996
,40973,DB00451,10025476,41,47230,10,15409,0.51542649,1.337622644,0.658732535,2.995600454,0.675204848,DB0045110025476_,0.392739155,0.290893892,NA,10025476,Malabsorption,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,41016,DB00682,10013710,196,19263,362,16002,5.76787395284576e-20,0.44978452,0.375618647,0.537355503,5.92220964259964e-18,DB0068210013710_,39.66782204,-0.798986655,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,41020,DB00264,10056819,81,29526,54,24838,0.195136732,1.261830368,0.882960578,1.815823378,0.343180049,DB0026410056819_,1.069500046,0.23256334,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,41021,DB00682,10056819,75,19384,32,16332,0.001233198,1.97465869,1.288497934,3.089422229,0.006541136,DB0068210056819_,5.029644394,0.680395568,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,41024,DB00377,10015150,42,1077,19,704,0.229965784,1.444672301,0.814109144,2.653006271,0.385943726,DB0037710015150_,0.952063709,0.367882515,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,palonosetron,DB00377
,41026,DB00927,10015150,90,7407,45,4971,0.112534766,1.342212553,0.926575119,1.968547772,0.229879644,DB0092710015150_,1.470199394,0.294319411,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,famotidine,DB00927
,41027,DB00958,10015150,84,4510,17,2568,2.44084481731095e-05,2.813167232,1.652309858,5.066371478,0.0002367,DB0095810015150_,8.348715934,1.034310977,female,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,carboplatin,DB00958
,41028,DB01229,10015150,130,5611,32,2677,0.000623905,1.938079727,1.303839113,2.958096355,0.003721628,DB0122910015150_,5.593594018,0.661697652,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,paclitaxel,DB01229
,41029,DB01234,10015150,250,31375,153,32735,1.73504088608775e-07,1.704787902,1.387706136,2.099931345,2.98758923621464e-06,DB0123410015150_,12.72104377,0.533440705,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,41030,DB00186,10060800,112,16789,23,9985,3.88365394951336e-07,2.895990521,1.835290946,4.75816541,6.15646684998359e-06,DB0018610060800_,11.99800751,1.063327201,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,lorazepam,DB00186
,41033,DB00927,10060800,38,7459,14,5002,0.064383656,1.820112729,0.962797459,3.640673192,0.151350392,DB0092710060800_,1.888157654,0.598898438,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,famotidine,DB00927
,41036,DB01234,10060800,123,31502,61,32827,1.26222089731539e-06,2.101168036,1.533014991,2.906177533,1.76054530570099e-05,DB0123410060800_,10.94730187,0.742493398,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,dexamethasone,DB01234
,41037,DB01067,10035598,20,4341,34,4789,0.133964133,0.648974551,0.353397466,1.162226613,0.261258884,DB0106710035598_,1.342243472,-0.432361776,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glipizide,DB01067
,41044,DB00338,10043882,91,33583,54,22218,0.553014371,1.114915045,0.787236071,1.592203264,0.70667072,DB0033810043882_,0.347190464,0.108778209,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,omeprazole,DB00338
,41046,DB00338,10060800,176,33498,58,22214,1.67869901809776e-06,2.012268692,1.486938559,2.75777048,2.275637116591e-05,DB0033810060800_,10.6906654,0.699262788,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,omeprazole,DB00338
,41049,DB00512,10011906,92,4645,111,4987,0.435333976,0.889864403,0.665557813,1.187432946,0.603743659,DB0051210011906_,0.504605577,-0.116686184,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,41059,DB00773,10040047,136,2187,158,2669,0.717342978,1.050484837,0.823091529,1.339230519,0.832962701,DB0077310040047_,0.182766414,0.049251807,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,etoposide,DB00773
,41063,DB00181,10064685,33,9823,38,5833,0.006435811,0.515686934,0.313082067,0.845495601,0.025035561,DB0018110064685_,3.687458025,-0.662255415,NA,10064685,Device occlusion,10077536,Product issues,Prod,baclofen,DB00181
,41064,DB01065,10013709,208,4123,133,2918,0.398438652,1.106852665,0.881319577,1.393862565,0.568240687,DB0106510013709_,0.565210206,0.101520551,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,41065,DB01065,10044565,77,4254,41,3010,0.157691311,1.328799084,0.895442254,1.997275161,0.294372793,DB0106510044565_,1.222908313,0.28427559,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,melatonin,DB01065
,41066,DB00688,10003239,87,6403,41,5337,0.002339055,1.768593396,1.204331325,2.635166321,0.011052955,DB0068810003239_,4.50505744,0.570184539,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,mycophenolate mofetil,DB00688
,41073,DB00005,10016970,161,127921,38,42381,0.059360342,1.403665071,0.980370091,2.055775529,0.142303487,DB0000510016970_,1.949793272,0.339086724,NA,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,41085,DB00683,10038695,60,1524,60,1578,0.853053605,1.035432242,0.706496497,1.517445395,0.928180234,DB0068310038695_,0.074529347,0.034818965,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,midazolam,DB00683
,41087,DB01202,10038695,75,6639,86,5632,0.066871528,0.73983782,0.534322943,1.02249408,0.155708739,DB0120210038695_,1.859768072,-0.301324279,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levetiracetam,DB01202
,41090,DB09153,10038695,94,7705,116,5583,0.000136398,0.587208506,0.441537932,0.779257431,0.001039196,DB0915310038695_,6.869307842,-0.532375316,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,41114,DB00983,10057362,73,3428,46,1694,0.201848367,0.784280213,0.532305815,1.165796516,0.351238558,DB0098310057362_,1.046289635,-0.242988908,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,formoterol,DB00983
,41118,DB01222,10003239,254,9020,82,5323,1.02567439322919e-06,1.827902096,1.416271849,2.379880969,1.46242752514398e-05,DB0122210003239_,11.13282772,0.603168914,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,budesonide,DB01222
,41119,DB06228,10022840,34,15878,28,16048,0.447557766,1.22727653,0.721951728,2.102094106,0.61531017,DB0622810022840_,0.485628796,0.204797511,NA,10022840,Intraventricular haemorrhage,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,41123,DB00279,10016256,112,1125,13,203,0.187186247,1.554166108,0.851933645,3.068629122,0.332996548,DB0027910016256_,1.099623155,0.440939137,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,liothyronine,DB00279
,41130,DB00181,10010305,178,9678,129,5742,0.095085107,0.818688147,0.6474059,1.037549345,0.203345663,DB0018110010305_,1.592847974,-0.200052041,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,41131,DB00586,10010305,71,7038,34,2771,0.383341246,0.822224239,0.537600923,1.279622165,0.553405853,DB0058610010305_,0.591663636,-0.195742125,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,diclofenac,DB00586
,41132,DB00181,10013916,43,9813,35,5836,0.196366818,0.730692391,0.456206524,1.17757824,0.344612827,DB0018110013916_,1.065333731,-0.313762714,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,41134,DB00181,10028836,74,9782,29,5842,0.065242241,1.523900137,0.978284031,2.432089454,0.15286537,DB0018110028836_,1.878197676,0.421272928,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,41135,DB00586,10028836,65,7044,22,2783,0.632562969,1.167281813,0.708542652,1.992519923,0.771264386,DB0058610028836_,0.25972405,0.154677809,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,41142,DB00586,10070863,45,7064,54,2751,5.48464068980666e-08,0.32455006,0.213000893,0.492512261,1.05254634617966e-06,DB0058610070863_,13.76429824,-1.125315486,male,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,diclofenac,DB00586
,41146,DB01222,10013911,36,9238,24,5381,0.594838067,0.873740463,0.506483355,1.532645543,0.74054655,DB0122210013911_,0.300366784,-0.134971901,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,41148,DB00060,10024860,38,9470,14,2451,0.300522421,0.702527551,0.371371077,1.406009077,0.466733543,DB0006010024860_,0.761996756,-0.35307066,NA,10024860,Loss of control of legs,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,41150,DB00787,10000059,145,16855,114,17134,0.045735096,1.292970471,1.00371128,1.668853018,0.116973915,DB0078710000059_,2.145804316,0.256942262,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,41151,DB01015,10016256,521,9366,424,8957,0.016274612,1.175103754,1.02828579,1.343459843,0.052537752,DB0101510016256_,2.946223286,0.161356445,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,41156,DB00480,10028334,1206,66222,1004,66658,1.08374850459203e-05,1.209100125,1.110276427,1.316930056,0.000116318,DB0048010028334_,9.059180939,0.189876384,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,41157,DB00787,10028334,344,16656,267,16981,0.000932983,1.313514178,1.114559266,1.549327554,0.005201159,DB0078710028334_,5.258873758,0.272706124,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,41158,DB01015,10028334,118,9769,80,9301,0.021990109,1.404308233,1.046777112,1.892124555,0.066610201,DB0101510028334_,2.708897543,0.339544821,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfamethoxazole,DB01015
,41159,DB01373,10028334,507,22213,95,7286,1.63515664658466e-07,1.75039612,1.401115151,2.206492707,2.83416369637176e-06,DB0137310028334_,12.77376366,0.559842117,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,41160,DB00169,10035742,47,38644,54,18121,8.63569716539775e-06,0.408139631,0.269962744,0.615128047,9.55342171685522e-05,DB0016910035742_,9.25602608,-0.89614593,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,41161,DB00787,10035742,37,16963,44,17204,0.505639599,0.852860988,0.535309547,1.35203375,0.666486316,DB0078710035742_,0.405735671,-0.159158714,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,41162,DB01015,10035742,25,9862,44,9337,0.015248741,0.53795598,0.315269914,0.8993258,0.049948677,DB0101510035742_,2.996759254,-0.619978545,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,41163,DB01373,10035742,31,22689,23,7358,0.003813005,0.437107432,0.246560756,0.785580919,0.016410127,DB0137310035742_,4.109856663,-0.827576274,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,41164,DB00169,10040808,48,38643,41,18134,0.006015645,0.549365987,0.354415844,0.855169303,0.023711663,DB0016910040808_,3.741788224,-0.598990416,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cholecalciferol,DB00169
,41167,DB01373,10040808,36,22684,18,7363,0.15288502,0.649190667,0.358877934,1.215110123,0.288018832,DB0137310040808_,1.244729413,-0.43202882,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,calcium,DB01373
,41168,DB00019,10033371,280,18732,102,9427,0.005282229,1.381475637,1.095863941,1.752902214,0.021370385,DB0001910033371_,3.845749213,0.32315223,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,41185,DB00373,10013573,40,1792,31,1256,0.715136772,0.904408398,0.548375737,1.504147207,0.831263877,DB0037310013573_,0.184807993,-0.100474253,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,timolol,DB00373
,41186,DB00654,10013573,101,3715,75,2523,0.586076328,0.914587126,0.668628993,1.255625619,0.733315171,DB0065410013573_,0.310179695,-0.089282544,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,latanoprost,DB00654
,41203,DB00635,10011878,59,32994,36,23758,0.467329621,1.180092171,0.7665018,1.839795387,0.633862859,DB0063510011878_,0.455922658,0.165592547,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,prednisone,DB00635
,41220,DB00273,10047895,189,8292,46,2147,0.744721548,1.063803702,0.764233043,1.507606932,0.854225564,DB0027310047895_,0.157559994,0.061850883,NA,10047895,Weight decreased,10022891,Investigations,Inv,topiramate,DB00273
,41221,DB00956,10047895,130,5684,85,3382,0.521178623,0.910016362,0.684604968,1.214848446,0.680064167,DB0095610047895_,0.385568122,-0.094292699,NA,10047895,Weight decreased,10022891,Investigations,Inv,hydrocodone,DB00956
,41227,DB00656,10028596,62,11951,52,6567,0.030321221,0.65515337,0.44530456,0.967354847,0.085386039,DB0065610028596_,2.460572664,-0.422885919,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,trazodone,DB00656
,41228,DB00999,10028596,102,21328,117,12122,2.96832855473597e-07,0.495493464,0.375827917,0.652427671,4.85025086955281e-06,DB0099910028596_,12.23648013,-0.702201116,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,41233,DB00181,10013983,33,9823,25,5846,0.414628794,0.785602301,0.452634541,1.37943238,0.583854383,DB0018110013983_,0.538103671,-0.241304592,NA,10013983,Dystonia,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,41234,DB00181,10014625,64,9792,59,5812,0.018909383,0.643891478,0.44419999,0.934660324,0.059135412,DB0018110014625_,2.82792535,-0.440225079,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,41235,DB00181,10041349,216,9640,166,5705,0.013692523,0.770088041,0.624374468,0.951100309,0.045737447,DB0018110041349_,3.084837914,-0.261250432,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,41248,DB00482,10028596,46,8213,37,3034,0.000696275,0.459299101,0.290854416,0.72982591,0.004073807,DB0048210028596_,5.503177286,-0.778053645,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,celecoxib,DB00482
,41252,DB01306,10028596,47,4161,53,3813,0.315184996,0.812649761,0.535414122,1.230024596,0.482773673,DB0130610028596_,0.728207321,-0.20745506,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,insulin aspart,DB01306
,41269,DB00030,10007559,30,2176,32,1789,0.368202358,0.770821434,0.450556613,1.315478053,0.537931744,DB0003010007559_,0.620023596,-0.260298535,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,insulin human,DB00030
,41271,DB00030,10011906,74,2132,99,1722,0.001327446,0.60381557,0.437569855,0.830221485,0.006955429,DB0003010011906_,4.968232815,-0.504486475,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,insulin human,DB00030
,41273,DB00335,10011906,277,8189,266,5199,2.92014068490528e-06,0.66117157,0.554681641,0.788185941,3.70086296541636e-05,DB0033510011906_,10.20435944,-0.413741911,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,41274,DB00404,10011906,1065,18827,813,9049,3.19752028402061e-21,0.629616308,0.572162333,0.693033555,3.81164719571345e-19,DB0040410011906_,42.41105534,-0.462644679,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,41275,DB00030,10028596,19,2187,32,1789,0.01531001,0.485778668,0.259198209,0.8869316,0.05012126,DB0003010028596_,2.99331,-0.722002174,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,insulin human,DB00030
,41277,DB01175,10028596,39,10685,50,4842,1.48100807019061e-06,0.353489744,0.226102502,0.549081566,2.0359561493586e-05,DB0117510028596_,10.8019599,-1.039900807,male,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,escitalopram,DB01175
,41280,DB00264,10037423,210,29397,147,24745,0.088298411,1.20249881,0.968632824,1.495935414,0.19241616,DB0026410037423_,1.648094753,0.184401733,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,41281,DB01175,10037423,38,10686,13,4879,0.450115623,1.334644951,0.69465408,2.733005305,0.617773498,DB0117510037423_,0.481633397,0.288665302,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,41282,DB00030,10038435,30,2176,21,1800,0.575112531,1.181673556,0.651849879,2.179705073,0.724646567,DB0003010038435_,0.322071237,0.166931702,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,insulin human,DB00030
,41284,DB00404,10038435,128,19764,56,9806,0.479729647,1.134055596,0.821404502,1.583106434,0.64460146,DB0040410038435_,0.439123044,0.12580023,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,alprazolam,DB00404
,41285,DB01175,10038435,41,10683,26,4866,0.188624102,0.718274277,0.428443425,1.224546352,0.334806666,DB0117510038435_,1.09420203,-0.330903781,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,escitalopram,DB01175
,41288,DB00335,10038695,36,8430,42,5423,0.010141476,0.551441172,0.342784086,0.882975953,0.035973127,DB0033510038695_,3.324983099,-0.595220116,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atenolol,DB00335
,41289,DB00404,10038695,97,19795,63,9799,0.109228824,0.762215075,0.548852006,1.064964875,0.224874065,DB0040410038695_,1.492214743,-0.271526513,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,41290,DB01175,10038695,53,10671,48,4844,0.000756194,0.501233045,0.332197,0.757985965,0.004362722,DB0117510038695_,5.434659134,-0.690684126,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,41305,DB01254,10013709,62,3405,90,3058,0.003964198,0.618735874,0.438636975,0.868037912,0.016956703,DB0125410013709_,4.077092073,-0.480076795,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dasatinib,DB01254
,41306,DB01098,10017944,40,8109,26,7183,0.2658895,1.362748265,0.810499294,2.328416894,0.427976242,DB0109810017944_,0.848687595,0.309503444,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,41307,DB00497,10061394,44,19223,23,16352,0.065272969,1.627299837,0.961142766,2.824565363,0.152907623,DB0049710061394_,1.877921312,0.4869221,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,41308,DB00073,10009887,43,7363,46,6361,0.338009621,0.807587336,0.519541538,1.2531601,0.507096424,DB0007310009887_,0.679054108,-0.213704074,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,rituximab,DB00073
,41309,DB00073,10029354,188,7218,267,6140,9.92448527578111e-08,0.59899051,0.492746569,0.726936198,1.7965915666247e-06,DB0007310029354_,13.22961926,-0.512509524,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,rituximab,DB00073
,41310,DB01273,10016322,88,1952,32,1243,0.007237259,1.750874826,1.148081407,2.730244181,0.027484121,DB0127310016322_,3.594146852,0.560115564,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,varenicline,DB01273
,41321,DB00776,10025482,43,1862,21,1318,0.199554578,1.449227965,0.836799117,2.583759398,0.348505726,DB0077610025482_,1.054100619,0.371030976,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,oxcarbazepine,DB00776
,41322,DB14512,10025482,129,4715,45,2367,0.041383105,1.439041452,1.013578609,2.075771583,0.108504231,DB1451210025482_,2.220966112,0.363977233,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,41327,DB00635,10039227,49,33004,18,23776,0.012983542,1.96104903,1.12187832,3.577863092,0.043834359,DB0063510039227_,3.127337316,0.673479549,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,41328,DB00005,10040744,123,127959,19,42400,0.00092235,2.144947629,1.316641381,3.684563383,0.005155551,DB0000510040744_,5.26768132,0.763115136,NA,10040744,Sinus headache,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,41333,DB00005,10005802,47,128035,6,42413,0.024712768,2.594989947,1.107068287,7.428769285,0.072859076,DB0000510005802_,2.619228166,0.953582643,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,etanercept,DB00005
,41339,DB00559,10039163,137,9522,57,3249,0.213597586,0.820091939,0.596291147,1.140595695,0.365747862,DB0055910039163_,1.005811084,-0.198338824,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,bosentan,DB00559
,41348,DB00530,10037660,33,1775,31,1237,0.249629368,0.741947195,0.437936882,1.259885044,0.409109825,DB0053010037660_,0.893771638,-0.298477204,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,erlotinib,DB00530
,41349,DB00564,10037660,49,2555,28,1435,1,0.982873323,0.602579519,1.631858052,1,DB0056410037660_,0,-0.017275035,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,carbamazepine,DB00564
,41354,DB01075,10045555,81,19867,90,11007,6.34408146922066e-06,0.498630218,0.364365272,0.68146137,7.29617945388164e-05,DB0107510045555_,9.525574616,-0.695890504,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,41358,DB08934,10033425,38,4451,31,6173,0.03670699,1.699920246,1.028254198,2.830224924,0.098968431,DB0893410033425_,2.312954356,0.530581336,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sofosbuvir,DB08934
,41364,DB00230,10020765,69,19605,35,8616,0.522290877,0.866418122,0.568376452,1.342187103,0.680939225,DB0023010020765_,0.384282221,-0.143387668,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,41365,DB00230,10033775,440,19234,155,8496,0.017044262,1.253869948,1.03986553,1.518483904,0.05450224,DB0023010033775_,2.909513474,0.226234727,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,41366,DB00230,10043882,49,19625,31,8620,0.114868127,0.694281145,0.433612029,1.12716509,0.233457723,DB0023010043882_,1.454754277,-0.364878292,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,pregabalin,DB00230
,41367,DB00230,10049848,238,19436,87,8564,0.146113882,1.205366345,0.937800186,1.561319162,0.278587217,DB0023010049848_,1.2780241,0.186783542,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,41368,DB00230,10061818,102,19572,53,8598,0.336280655,0.845467801,0.600273622,1.202810717,0.505338994,DB0023010061818_,0.682525801,-0.167865194,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,41370,DB00829,10022523,45,8007,33,4421,0.23576341,0.752960133,0.469119796,1.219906926,0.392901647,DB0082910022523_,0.934195961,-0.283742996,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,41371,DB00829,10042464,46,8006,25,4429,1,1.017905578,0.611525011,1.731487833,1,DB0082910042464_,0,0.017747161,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,41377,DB01075,10073302,81,19867,49,11048,0.647323796,0.91926814,0.636415712,1.339861577,0.7825426,DB0107510073302_,0.245206917,-0.084177426,NA,10073302,Exposure via ingestion,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,41378,DB00374,10037423,240,17476,60,5664,0.078491661,1.296380591,0.971588427,1.753152081,0.175841925,DB0037410037423_,1.738169843,0.25957622,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,41381,DB00005,10043239,49,128033,14,42405,0.770610305,1.159209347,0.629730795,2.273847435,0.874325198,DB0000510043239_,0.134302893,0.147738175,NA,10043239,Tendon disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,41382,DB00005,10056819,188,127894,56,42363,0.553239168,1.112002342,0.820924988,1.527106204,0.706877869,DB0000510056819_,0.346897374,0.106162302,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,41385,DB00051,10000059,285,25446,88,11332,0.002302989,1.442293495,1.130609761,1.855255842,0.010909005,DB0005110000059_,4.518166678,0.366234551,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,41398,DB00099,10053762,351,2034,212,1743,0.000161325,1.418670049,1.178433336,1.710789135,0.001200745,DB0009910053762_,6.724813151,0.349719848,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,filgrastim,DB00099
,41400,DB00028,10043607,93,13365,39,5576,1,0.99488354,0.676646439,1.487532698,1,DB0002810043607_,0,-0.005129594,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,human immunoglobulin g,DB00028
,41401,DB00959,10043607,32,8046,35,4967,0.02270839,0.564459641,0.337856378,0.939998543,0.0682199,DB0095910043607_,2.685018962,-0.571886394,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,methylprednisolone,DB00959
,41407,DB00455,10018884,90,9311,51,5067,0.859457256,0.960366924,0.672502586,1.384372576,0.933447678,DB0045510018884_,0.068870367,-0.040439856,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,loratadine,DB00455
,41409,DB00005,10060708,43,128039,11,42408,0.530078789,1.294722692,0.65651143,2.784316493,0.687176433,DB0000510060708_,0.375164204,0.258296535,NA,10060708,Induration,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,41411,DB00005,10012431,58,128024,18,42401,0.89482627,1.067180419,0.619776718,1.924900762,0.955976233,DB0000510012431_,0.045022227,0.065020048,NA,10012431,Dermatitis,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,41413,DB00028,10002198,76,13382,36,5579,0.533452847,0.880144495,0.583810598,1.349119042,0.690188759,DB0002810002198_,0.370790155,-0.127669186,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,human immunoglobulin g,DB00028
,41414,DB00028,10003553,115,13343,17,5598,8.47628611870048e-06,2.837862854,1.695417236,5.043894062,9.39886899017266e-05,DB0002810003553_,9.272336103,1.043051253,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human immunoglobulin g,DB00028
,41415,DB00341,10003553,165,11240,60,5008,0.190876914,1.225231417,0.904727104,1.678471606,0.337653927,DB0034110003553_,1.085733794,0.203129738,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,41420,DB00563,10047461,98,46548,47,15301,0.042453085,0.685409423,0.47909066,0.992784622,0.110598082,DB0056310047461_,2.20185253,-0.377738922,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,41422,DB00736,10005191,47,10544,13,5540,0.040722952,1.899517739,1.009994748,3.830375415,0.107088941,DB0073610005191_,2.234095562,0.641600033,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,esomeprazole,DB00736
,41425,DB00443,10033371,87,2059,20,1170,0.000127932,2.471254893,1.497315624,4.266406404,0.000984392,DB0044310033371_,6.923486808,0.904726075,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,betamethasone,DB00443
,41427,DB01590,10035598,57,4681,32,2835,0.825991576,1.078795282,0.685924001,1.723661556,0.908151946,DB0159010035598_,0.096343573,0.075844939,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,everolimus,DB01590
,41429,DB01238,10043118,126,5124,65,3437,0.100212386,1.300213665,0.953190394,1.787744936,0.211098138,DB0123810043118_,1.555432146,0.262528609,NA,10043118,Tardive dyskinesia,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,41430,DB01267,10043118,36,2816,51,3664,0.744601392,0.918439818,0.580554083,1.439496348,0.854143649,DB0126710043118_,0.157655892,-0.085078898,NA,10043118,Tardive dyskinesia,10029205,Nervous system disorders,Nerv,paliperidone,DB01267
,41432,DB00668,10011224,174,9917,87,4216,0.2199967,0.850282174,0.651869138,1.115800646,0.37343321,DB0066810011224_,0.985016112,-0.162187015,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,41433,DB00959,10011224,201,7877,104,4898,0.136422941,1.201717761,0.941063411,1.542114614,0.264691441,DB0095910011224_,1.329190506,0.183752001,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,41434,DB01015,10011224,178,9709,169,9212,1,0.999338776,0.803444054,1.243378425,1,DB0101510011224_,0,-0.000661443,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,41444,DB00668,10051792,117,9974,53,4250,0.736144888,0.940658571,0.67294425,1.329851417,0.847624338,DB0066810051792_,0.16531774,-0.061175041,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,epinephrine,DB00668
,41445,DB00959,10051792,180,7898,123,4879,0.40273843,0.904035117,0.712720746,1.149774648,0.572509107,DB0095910051792_,0.557726636,-0.100887074,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,methylprednisolone,DB00959
,41447,DB01075,10051792,467,19481,333,10764,0.000504456,0.7749059,0.67045749,0.896343101,0.00311186,DB0107510051792_,5.772534665,-0.255013676,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,41456,DB00668,10062355,62,10029,24,4279,0.724789706,1.102202529,0.6769969,1.849189438,0.838571976,DB0066810062355_,0.176054863,0.097310477,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,41457,DB00959,10062355,44,8034,18,4984,0.150411503,1.516397718,0.85732194,2.791567006,0.284521345,DB0095910062355_,1.256947002,0.4163376,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,41458,DB01015,10062355,41,9846,42,9339,0.742480703,0.925947784,0.586632511,1.46052755,0.852455023,DB0101510062355_,0.159634831,-0.076937434,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,41459,DB00559,10061024,156,9503,66,3240,0.161750639,0.805869086,0.598821074,1.094767611,0.29974729,DB0055910061024_,1.204815527,-0.215833973,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,bosentan,DB00559
,41462,DB09068,10012735,85,2310,39,947,0.547809531,0.893532523,0.599760138,1.351549495,0.702364446,DB0906810012735_,0.353302855,-0.112572546,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,vortioxetine,DB09068
,41464,DB09068,10044565,41,2354,17,969,1,0.992780313,0.548564518,1.873418092,1,DB0906810044565_,0,-0.007245875,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,vortioxetine,DB09068
,41465,DB08828,10011906,69,693,118,1024,0.387637566,0.864119206,0.622474316,1.192364314,0.557649468,DB0882810011906_,0.584024708,-0.14604455,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,vismodegib,DB08828
,41466,DB09068,10010264,47,2348,18,968,0.890688774,1.07644768,0.609829475,1.979905034,0.954671384,DB0906810010264_,0.046388098,0.073666435,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,vortioxetine,DB09068
,41472,DB00289,10028813,33,450,21,542,0.025315717,1.891518646,1.045479643,3.492170774,0.074195643,DB0028910028813_,2.601049844,0.637380023,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,atomoxetine,DB00289
,41473,DB00697,10013700,241,5855,40,1766,0.000285219,1.817065492,1.290017743,2.618495805,0.001936204,DB0069710013700_,6.247026099,0.597222833,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,tizanidine,DB00697
,41474,DB08895,10019044,44,28070,17,6629,0.101011572,0.611248259,0.342009086,1.141901221,0.212322206,DB0889510019044_,1.54965032,-0.492252087,NA,10019044,Hair growth abnormal,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,41476,DB01233,10021789,42,3379,14,1712,0.201077267,1.519861722,0.810964532,3.021959194,0.350287699,DB0123310021789_,1.049000464,0.418619358,NA,10021789,Infection,10021881,Infections and infestations,Infec,metoclopramide,DB01233
,41477,DB06643,10021789,141,52280,25,7490,0.346470478,0.80802963,0.525028831,1.291858671,0.515917546,DB0664310021789_,0.661808322,-0.21315655,NA,10021789,Infection,10021881,Infections and infestations,Infec,denosumab,DB06643
,41480,DB00588,10060795,53,16471,32,8436,0.491364027,0.848301804,0.53648306,1.36074266,0.654512919,DB0058810060795_,0.423863955,-0.164518806,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,41486,DB00794,10011906,39,797,40,569,0.127993227,0.696269941,0.430157695,1.126060881,0.252840972,DB0079410011906_,1.374994557,-0.362017848,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,primidone,DB00794
,41498,DB00213,10018964,53,18842,47,13374,0.265753301,0.800421609,0.529874334,1.212450635,0.427838887,DB0021310018964_,0.849008586,-0.222616679,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,41499,DB00421,10018964,48,8855,23,5229,0.461007703,1.232395076,0.734113469,2.125298001,0.628293753,DB0042110018964_,0.464747462,0.208959492,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,41501,DB01240,10018964,79,5672,34,1542,0.02849437,0.631723944,0.415734898,0.978172254,0.081366052,DB0124010018964_,2.508797148,-0.459302778,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,41502,DB09140,10018964,56,3685,20,1778,0.269230106,1.350951155,0.795199622,2.384613275,0.431757015,DB0914010018964_,0.839892315,0.300808903,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,41505,DB00695,10061603,33,28016,30,20498,0.444134499,0.804827739,0.47569334,1.366561256,0.612137555,DB0069510061603_,0.490798259,-0.217127014,NA,10061603,Respiratory syncytial virus infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,41509,DB00555,10037087,110,6937,42,3444,0.164871876,1.300283513,0.901170219,1.906974986,0.303969155,DB0055510037087_,1.190829046,0.262582327,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,lamotrigine,DB00555
,41510,DB01175,10037087,205,10519,43,4849,5.62443760095895e-07,2.197579203,1.572277071,3.134262273,8.61779902892486e-06,DB0117510037087_,11.66168084,0.787356392,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,escitalopram,DB01175
,41512,DB00722,10060800,136,25267,48,25984,1.27307960367473e-11,2.913766664,2.081406578,4.140561512,4.77359449109706e-10,DB0072210060800_,21.46275135,1.06944663,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,lisinopril,DB00722
,41513,DB00335,10000081,128,8338,53,5412,0.005720167,1.567531778,1.127390081,2.206029707,0.02278963,DB0033510000081_,3.78144967,0.449502267,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,41514,DB01068,10000081,183,13580,60,6780,0.0048507,1.522725112,1.130007799,2.076977418,0.019978227,DB0106810000081_,3.913112232,0.420501566,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,41515,DB01224,10000081,69,8039,40,5877,0.284168537,1.261059235,0.840842148,1.913904778,0.44866933,DB0122410000081_,0.80146912,0.23195203,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,quetiapine,DB01224
,41517,DB00722,10008796,29,25374,33,25999,0.704680778,0.900441085,0.527266875,1.530030813,0.822904333,DB0072210008796_,0.194915327,-0.104870541,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,41520,DB01068,10012378,422,13341,202,6638,0.666305905,1.039464913,0.874549129,1.238680618,0.797080474,DB0106810012378_,0.226799634,0.038706074,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,41525,DB01068,10037844,277,13486,97,6743,0.002295236,1.427811789,1.126869722,1.821922739,0.010881104,DB0106810037844_,4.520727541,0.356143055,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,clonazepam,DB01068
,41527,DB00722,10060795,85,25318,66,25966,0.102794756,1.320829545,0.945900002,1.851262981,0.215206335,DB0072210060795_,1.536158015,0.278259983,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,lisinopril,DB00722
,41529,DB00722,10061920,30,25373,34,25998,0.709145636,0.904098186,0.534270513,1.52273592,0.826419554,DB0072210061920_,0.1906527,-0.100817312,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,41530,DB01068,10061920,65,13698,41,6799,0.255170804,0.78692812,0.523653961,1.194678826,0.415857928,DB0106810061920_,0.877411596,-0.239618369,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,41531,DB01224,10061920,53,8055,72,5845,0.000520837,0.53418496,0.366787205,0.773615206,0.003193424,DB0122410061920_,5.74666145,-0.627013133,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,41532,DB00688,10019211,239,6251,114,5264,5.18675972225927e-07,1.765379576,1.402086164,2.23341188,8.00786956238384e-06,DB0068810019211_,11.7350858,0.568365724,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,mycophenolate mofetil,DB00688
,41533,DB00864,10019211,207,6662,173,8219,0.000202305,1.476120889,1.197182161,1.821873147,0.001455475,DB0086410019211_,6.532422832,0.389417626,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,tacrolimus,DB00864
,41534,DB00688,10043554,43,6447,52,5326,0.07805088,0.683167867,0.444467201,1.045186955,0.175108176,DB0068810043554_,1.742351348,-0.38101467,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,mycophenolate mofetil,DB00688
,41535,DB00864,10043554,83,6786,96,8296,0.762553073,1.056931887,0.776842863,1.435566425,0.868520129,DB0086410043554_,0.140964517,0.055370265,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,tacrolimus,DB00864
,41536,DB00904,10043554,276,22793,241,14215,0.000184702,0.714253946,0.597925196,0.853640228,0.001348394,DB0090410043554_,6.608840925,-0.336516713,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,ondansetron,DB00904
,41541,DB06616,10000059,15,946,38,765,0.000118496,0.31940971,0.161927023,0.599670305,0.000921637,DB0661610000059_,6.989359493,-1.141280644,male,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,bosutinib,DB06616
,41546,DB00437,10007554,39,6882,81,11465,0.29803104,0.802151002,0.53222538,1.190840977,0.463947046,DB0043710007554_,0.767984858,-0.220458407,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,allopurinol,DB00437
,41561,DB00814,10007559,30,8257,24,3391,0.016311393,0.513361605,0.289710651,0.919102316,0.052616429,DB0081410007559_,2.944726878,-0.666774798,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,meloxicam,DB00814
,41562,DB01137,10007559,44,7728,47,5546,0.069346403,0.671876192,0.434381546,1.037392764,0.160159055,DB0113710007559_,1.831587862,-0.397681193,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,levofloxacin,DB01137
,41564,DB00973,10008190,56,3795,30,2991,0.100819367,1.47111637,0.925352563,2.381046319,0.212079313,DB0097310008190_,1.550794956,0.386021548,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,ezetimibe,DB00973
,41565,DB01098,10008190,93,8056,79,7130,0.817985883,1.041906178,0.762230583,1.427127221,0.902843181,DB0109810008190_,0.102206405,0.041051899,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,41566,DB01137,10008190,40,7732,27,5566,0.901320452,1.066474348,0.637582033,1.809511054,0.956927891,DB0113710008190_,0.044027239,0.064358207,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,41569,DB00682,10011078,23,19436,49,16315,0.000193211,0.394022879,0.229029591,0.659514324,0.001399286,DB0068210011078_,6.57179294,-0.931346302,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,warfarin,DB00682
,41572,DB00193,10028596,86,19234,69,8633,0.000458196,0.559463383,0.402368589,0.780273912,0.00287112,DB0019310028596_,5.853053145,-0.580777199,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,tramadol,DB00193
,41574,DB00264,10040979,78,29529,43,24849,0.028039278,1.526447823,1.03843839,2.270260459,0.080310823,DB0026410040979_,2.521850885,0.422943352,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,41575,DB00316,10040979,131,65343,96,36857,0.052867686,0.769719071,0.586815417,1.012621504,0.130438552,DB0031610040979_,2.036853026,-0.261729673,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,41576,DB00331,10040979,69,24877,56,20696,0.928468161,1.025062745,0.709724477,1.486174295,0.9702149,DB0033110040979_,0.030237685,0.024753825,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,41577,DB00381,10040979,60,29300,51,22836,0.701898732,0.916926378,0.620452987,1.35962298,0.821068454,DB0038110040979_,0.197148794,-0.086728096,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,41581,DB00682,10040979,44,19415,37,16327,1,1.000061039,0.630818135,1.593344191,1,DB0068210040979_,0,6.10370189713741e-05,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,41582,DB00695,10040979,93,27956,55,20473,0.212694771,1.238296468,0.877439209,1.762157431,0.3646533,DB0069510040979_,1.008808241,0.213736619,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,41585,DB00999,10040979,70,21360,40,12199,1,0.999449915,0.667840289,1.514068631,1,DB0099910040979_,0,-0.000550237,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,41589,DB00678,10033318,67,15532,28,10696,0.027696118,1.647791265,1.044737003,2.662663734,0.079562017,DB0067810033318_,2.531218479,0.499435764,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,losartan,DB00678
,41590,DB00999,10033318,68,21362,21,12218,0.011170988,1.851996836,1.120591409,3.183328569,0.038888737,DB0099910033318_,3.24705061,0.616264428,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,41591,DB01409,10033318,96,5935,61,3905,0.869617349,1.035479378,0.741429356,1.455559636,0.94203021,DB0140910033318_,0.059717935,0.034864487,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,tiotropium,DB01409
,41601,DB06724,10008190,66,7863,38,3881,0.464400349,0.857286864,0.565528637,1.316135079,0.631509516,DB0672410008190_,0.459642269,-0.153982686,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,41606,DB00531,10061819,39,7213,31,6485,0.633064467,1.131075603,0.686822937,1.877267861,0.771750551,DB0053110061819_,0.259093901,0.123169041,NA,10061819,Disease recurrence,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,41608,DB00231,10037844,77,3219,39,2100,0.212840985,1.287966673,0.861545283,1.952928912,0.364836708,DB0023110037844_,1.008305401,0.253064752,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,temazepam,DB00231
,41609,DB00881,10012735,34,678,28,562,1,1.00652701,0.584345326,1.746313247,1,DB0088110012735_,0,0.006505801,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,quinapril,DB00881
,41610,DB01050,10012735,799,17309,364,9007,0.039940618,1.142244825,1.005091131,1.299936187,0.105553905,DB0105010012735_,2.248533513,0.132995471,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,41611,DB00881,10016256,57,655,45,545,0.836319398,1.053916426,0.688158379,1.622051094,0.915505295,DB0088110016256_,0.088279131,0.052513155,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,quinapril,DB00881
,41612,DB01016,10016256,46,1055,64,1164,0.281835626,0.793089174,0.525784583,1.188353871,0.445811484,DB0101610016256_,0.807859097,-0.231819612,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,glyburide,DB01016
,41615,DB00264,10020635,65,29542,79,24813,0.02927227,0.691087257,0.489723058,0.972365056,0.083090887,DB0026410020635_,2.48782025,-0.369489187,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,41617,DB00999,10020635,41,21389,26,12213,0.703587016,0.900419572,0.537484892,1.533938156,0.822205647,DB0099910020635_,0.195764736,-0.104894433,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,41621,DB00126,10025482,348,9823,143,5802,0.000250556,1.437365998,1.17638556,1.763567064,0.001739071,DB0012610025482_,6.354404274,0.36281227,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,41623,DB01016,10025482,38,1063,25,1203,0.04044125,1.719770597,1.003900941,2.994057367,0.106539541,DB0101610025482_,2.239239089,0.542190908,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,glyburide,DB01016
,41624,DB01050,10025482,458,17650,196,9175,0.02416902,1.214662734,1.023312743,1.446137353,0.071619118,DB0105010025482_,2.636393226,0.194466453,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,41625,DB00175,10028334,150,7981,95,6011,0.193532607,1.189190163,0.911469975,1.55783247,0.341089217,DB0017510028334_,1.075611203,0.17327254,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,41626,DB00331,10028334,311,24635,210,20542,0.018994619,1.234891744,1.032202378,1.479742896,0.059345485,DB0033110028334_,2.82437923,0.21098331,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,41629,DB08907,10028334,34,4219,20,3890,0.132322781,1.567342437,0.874997785,2.878866766,0.25907667,DB0890710028334_,1.350631238,0.44938147,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,canagliflozin,DB08907
,41637,DB08865,10011224,34,1177,24,947,0.688836152,1.139750423,0.651230305,2.023948931,0.812422689,DB0886510011224_,0.207734522,0.130809312,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,crizotinib,DB08865
,41638,DB08865,10013968,50,1161,30,941,0.20929361,1.350662399,0.834670711,2.219035176,0.360349952,DB0886510013968_,1.020679631,0.300595138,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,crizotinib,DB08865
,41640,DB01238,10022437,132,5118,95,3407,0.583245919,0.924967362,0.702534745,1.221625666,0.731335432,DB0123810022437_,0.312883057,-0.077996827,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,41641,DB00182,10033557,64,5130,17,2835,0.006849985,2.080327403,1.200920797,3.796751533,0.026357131,DB0018210033557_,3.636016408,0.732525287,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,amphetamine,DB00182
,41642,DB01238,10033557,45,5205,19,3483,0.09689985,1.584782158,0.906567674,2.874181003,0.206110667,DB0123810033557_,1.579342038,0.460446958,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,aripiprazole,DB01238
,41647,DB00581,10000060,35,2078,34,2035,1,1.008108718,0.608004623,1.673215886,1,DB0058110000060_,0,0.008076019,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,lactulose,DB00581
,41648,DB00996,10000060,189,38764,109,22316,1,0.998212608,0.78398378,1.276227518,1,DB0099610000060_,0,-0.001788991,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,41651,DB00813,10000081,162,10410,99,10069,0.000364742,1.582718604,1.223108061,2.056563444,0.002373965,DB0081310000081_,6.043193835,0.459144004,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,41652,DB01060,10000081,108,8479,66,5015,0.874600783,0.967824453,0.704528801,1.33811043,0.945713704,DB0106010000081_,0.055815394,-0.032704559,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,41655,DB00213,10001053,119,18776,95,13326,0.404132703,0.889042384,0.672532857,1.177925541,0.573839403,DB0021310001053_,0.555405708,-0.117610369,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,41658,DB00813,10001053,42,10530,46,10122,0.593581187,0.877672475,0.563096026,1.364721133,0.739584827,DB0081310001053_,0.301666295,-0.13048179,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,41659,DB00904,10001053,125,22944,87,14369,0.479237167,0.899808935,0.678350789,1.198040816,0.644364554,DB0090410001053_,0.439490635,-0.105572833,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,41664,DB00213,10003598,34,18861,28,13393,0.606547727,0.862258393,0.507221535,1.476891693,0.749435072,DB0021310003598_,0.288435594,-0.148200293,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,41668,DB00904,10003598,50,23019,49,14407,0.02948301,0.638677463,0.421712291,0.967621231,0.083571759,DB0090410003598_,2.482049632,-0.448355704,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,41675,DB00213,10008629,41,18854,34,13387,0.557838769,0.856225878,0.529846815,1.391824862,0.710901105,DB0021310008629_,0.341221952,-0.155221062,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,pantoprazole,DB00213
,41679,DB00996,10008629,70,38883,37,22388,0.763218667,1.089319571,0.721052105,1.669842739,0.86890171,DB0099610008629_,0.140525267,0.085553255,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,gabapentin,DB00996
,41695,DB00213,10009887,77,18818,49,13372,0.587360958,1.116678677,0.769930074,1.633038466,0.73446144,DB0021310009887_,0.308617783,0.110358813,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,41698,DB00904,10009887,158,22911,93,14363,0.64929203,1.065068828,0.818464747,1.39250465,0.784181229,DB0090410009887_,0.243115126,0.063039424,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,41699,DB00996,10009887,78,38875,50,22375,0.581691326,0.897881941,0.621303,1.308085827,0.730012963,DB0099610009887_,0.314692987,-0.107716688,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,41703,DB00152,10012735,51,780,44,820,0.398294277,1.218386573,0.787867713,1.890583281,0.568096431,DB0015210012735_,0.565464103,0.197527502,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,thiamine,DB00152
,41704,DB00333,10012735,63,3008,59,3093,0.647904318,1.097945589,0.754592439,1.599475248,0.782960094,DB0033310012735_,0.24467355,0.093440787,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,methadone,DB00333
,41705,DB01220,10012735,94,1200,58,1078,0.029171561,1.455692659,1.026987065,2.077815877,0.082864497,DB0122010012735_,2.490548577,0.375481841,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,rifaximin,DB01220
,41708,DB00904,10016322,292,22777,121,14335,8.76369216884945e-05,1.518776287,1.223285198,1.895227143,0.000712948,DB0090410016322_,7.246101421,0.417904936,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,41709,DB01060,10016322,102,8485,47,5034,0.172562627,1.287525689,0.901078014,1.863271905,0.314222975,DB0106010016322_,1.157652435,0.252722306,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,41710,DB01068,10016322,345,13418,113,6727,7.07013013289489e-05,1.530614823,1.231576738,1.913970832,0.000591654,DB0106810016322_,7.432589365,0.4256695,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,41713,DB00213,10020919,130,18765,81,13340,0.363148211,1.140906545,0.857129699,1.526443617,0.532664662,DB0021310020919_,0.629863205,0.131823162,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,41715,DB00813,10020919,31,10541,26,10142,0.691054789,1.147167952,0.658640672,2.013077196,0.813688495,DB0081310020919_,0.20617767,0.137296255,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,fentanyl,DB00813
,41716,DB00904,10020919,117,22952,61,14395,0.248135537,1.202906523,0.874690528,1.668667328,0.407488789,DB0090410020919_,0.897741859,0.184740731,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,41725,DB00996,10019465,45,38908,37,22388,0.109261802,0.699850951,0.44275058,1.112338276,0.224924343,DB0099610019465_,1.491991188,-0.356887894,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,41733,DB00581,10019660,50,2063,72,1997,0.034551731,0.67229531,0.456521202,0.983412276,0.094529509,DB0058110019660_,2.358843227,-0.397057586,NA,10019660,Hepatic encephalopathy,10029205,Nervous system disorders,Nerv,lactulose,DB00581
,41741,DB00213,10019663,39,18856,38,13383,0.166544959,0.728443344,0.453595663,1.170740333,0.306192506,DB0021310019663_,1.18354127,-0.316845426,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,pantoprazole,DB00213
,41743,DB00581,10019663,28,2085,44,2025,0.056522141,0.618125563,0.368998791,1.01975383,0.136997008,DB0058110019663_,1.987796194,-0.481063666,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,lactulose,DB00581
,41744,DB00904,10019663,41,23028,34,14422,0.23610632,0.755241357,0.467379071,1.227594795,0.393360881,DB0090410019663_,0.933027817,-0.280717902,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,ondansetron,DB00904
,41752,DB00904,10023676,26,23043,30,14426,0.027047187,0.542603023,0.30808205,0.949603308,0.078120466,DB0090410023676_,2.549503206,-0.611377308,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,41753,DB00996,10023676,37,38916,32,22393,0.103486872,0.665360833,0.403116181,1.103549145,0.216260088,DB0099610023676_,1.531273485,-0.40742578,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,41759,DB00213,10040979,52,18843,33,13388,0.660170773,1.11960834,0.709743931,1.789002493,0.792536596,DB0021310040979_,0.232516596,0.112978928,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,41763,DB00904,10040979,46,23023,21,14435,0.258853335,1.373377104,0.802790718,2.423899373,0.41994568,DB0090410040979_,0.86762991,0.317272746,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,41765,DB01068,10040979,53,13710,41,6799,0.03668533,0.641060856,0.417929165,0.989542017,0.098944681,DB0106810040979_,2.31319436,-0.444630887,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,41768,DB00213,10049848,117,18778,62,13359,0.067722658,1.342501033,0.977682721,1.858822736,0.15723644,DB0021310049848_,1.850004619,0.294534317,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,41771,DB00813,10049848,39,10533,34,10134,0.725597418,1.103586769,0.678206547,1.803793788,0.839229435,DB0081310049848_,0.175271148,0.098565574,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,41772,DB00904,10049848,125,22944,65,14391,0.232392567,1.206156118,0.886166554,1.655105293,0.388828508,DB0090410049848_,0.944616887,0.187438541,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,41773,DB00996,10049848,399,38554,192,22233,0.043569205,1.198431635,1.005524032,1.432187881,0.112754749,DB0099610049848_,2.182540184,0.181013731,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,41775,DB01068,10049848,143,13620,69,6771,0.883570584,1.030264893,0.766546304,1.396064669,0.951303696,DB0106810049848_,0.049921923,0.029815946,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,41807,DB09068,10002368,38,2357,15,971,1,1.043611363,0.557781251,2.052222857,1,DB0906810002368_,0,0.042687163,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,vortioxetine,DB09068
,41812,DB00121,10003239,170,4053,13,455,0.209095157,1.467943174,0.826913359,2.837291229,0.360149812,DB0012110003239_,1.021235191,0.383862219,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,biotin,DB00121
,41813,DB00285,10003239,253,10698,43,3675,7.28808209419588e-06,2.021178951,1.454621998,2.867989928,8.21824272183349e-05,DB0028510003239_,9.40656906,0.703680981,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,venlafaxine,DB00285
,41814,DB00710,10003239,215,2191,8,193,0.012350698,2.366786296,1.155284488,5.638149361,0.042117811,DB0071010003239_,3.167284569,0.861533042,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ibandronate,DB00710
,41815,DB00788,10003239,361,8995,124,4937,5.09452287015146e-06,1.597843271,1.295384698,1.981571163,6.02517586690354e-05,DB0078810003239_,9.716978796,0.468654764,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,41816,DB01068,10003239,293,13470,94,6746,0.000131935,1.561024721,1.230918044,1.994755943,0.001010024,DB0106810003239_,6.897780921,0.445342478,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,41819,DB00404,10003285,79,19813,19,9843,0.003490682,2.065577048,1.23882794,3.612712987,0.015293371,DB0040410003285_,4.180335819,0.725409629,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,41821,DB01068,10003285,63,13700,13,6827,0.002152628,2.414853817,1.314365801,4.786872082,0.010333635,DB0106810003285_,4.572351157,0.881638754,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,41822,DB00121,10003988,115,4108,6,462,0.064525412,2.155288642,0.952803649,6.029645585,0.151615828,DB0012110003988_,1.886405405,0.767924655,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,biotin,DB00121
,41823,DB00285,10003988,179,10772,47,3671,0.123183135,1.297868565,0.934351045,1.834109348,0.24592653,DB0028510003988_,1.402722444,0.260723353,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,venlafaxine,DB00285
,41824,DB00788,10003988,234,9122,93,4968,0.011618156,1.370299063,1.070300466,1.766300566,0.040131839,DB0078810003988_,3.215585275,0.31502901,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,41825,DB08895,10003988,661,27453,155,6491,0.964080049,1.008304493,0.843382874,1.211489444,1,DB0889510003988_,0,0.0082702,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,41827,DB00285,10028391,46,10905,13,3705,0.65371533,1.202181042,0.637782987,2.428293867,0.787753851,DB0028510028391_,0.23856961,0.184137442,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,venlafaxine,DB00285
,41829,DB00788,10028391,63,9293,31,5030,0.745257379,1.099998707,0.703705512,1.752336542,0.854560494,DB0078810028391_,0.157167985,0.095309004,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,41830,DB01068,10028391,60,13703,25,6815,0.490733888,1.193577718,0.736382941,1.9885629,0.653947405,DB0106810028391_,0.424728352,0.176955282,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,41831,DB08895,10028391,413,27701,99,6547,0.909840777,0.985965355,0.788605355,1.242601427,0.959437782,DB0889510028391_,0.04140781,-0.014134062,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,41832,DB00285,10028836,50,10901,13,3705,0.468584809,1.307182392,0.698604586,2.626303141,0.635047781,DB0028510028836_,0.454055037,0.267873975,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,venlafaxine,DB00285
,41834,DB00788,10028836,76,9280,16,5045,0.000253824,2.582150826,1.490381516,4.750022973,0.001758501,DB0078810028836_,6.343293769,0.948622705,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,41835,DB01068,10028836,81,13682,32,6808,0.316447653,1.25946467,0.826066262,1.962499274,0.484143452,DB0106810028836_,0.725374029,0.230686766,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,41837,DB00285,10052904,68,10883,16,3702,0.209037573,1.445627928,0.828231001,2.674021802,0.36006284,DB0028510052904_,1.021476706,0.368543779,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,venlafaxine,DB00285
,41838,DB00404,10052904,122,19770,35,9827,0.003706744,1.732601759,1.180218639,2.602921462,0.016042217,DB0040410052904_,4.132531441,0.549624186,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,41840,DB00788,10052904,109,9247,37,5024,0.014385642,1.600517166,1.091200379,2.395276543,0.047637995,DB0078810052904_,3.044124614,0.470326805,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,41842,DB00656,10040108,120,11893,156,6463,9.26948771918439e-13,0.418039752,0.326063528,0.534881103,4.17544629491325e-11,DB0065610040108_,23.89921477,-0.872178751,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,41843,DB01175,10040108,71,10653,66,4826,3.94094940761126e-05,0.487348099,0.343003627,0.693308389,0.000359993,DB0117510040108_,7.929427232,-0.718776629,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,41867,DB00656,10013754,88,11925,39,6580,0.265899873,1.245074874,0.843664478,1.867220555,0.427976242,DB0065610013754_,0.848687595,0.219195668,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,41869,DB01238,10013754,37,5213,23,3479,0.894970489,1.073598291,0.62003317,1.896075329,0.955976233,DB0123810013754_,0.045022227,0.071015896,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,41870,DB00656,10047899,216,11797,76,6543,0.000541354,1.576287724,1.206035387,2.078987974,0.003295773,DB0065610047899_,5.715114603,0.455072541,NA,10047899,Weight increased,10022891,Investigations,Inv,trazodone,DB00656
,41871,DB00669,10047899,74,6303,14,1083,0.761294916,0.908194172,0.506406286,1.748160142,0.867650712,DB0066910047899_,0.141966051,-0.096297078,NA,10047899,Weight increased,10022891,Investigations,Inv,sumatriptan,DB00669
,41889,DB00476,10045555,44,17213,34,6143,0.001111043,0.461854476,0.28825452,0.745855696,0.0060053,DB0047610045555_,5.115112947,-0.772505424,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,41890,DB01195,10013709,53,1186,35,709,0.653918895,0.905299526,0.573372215,1.444901892,0.787852518,DB0119510013709_,0.238444366,-0.099489422,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,flecainide,DB01195
,41894,DB00281,10028596,46,11412,30,5641,0.27126208,0.757975021,0.467736445,1.2450315,0.434027292,DB0028110028596_,0.834647863,-0.277104847,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,lidocaine,DB00281
,41895,DB00472,10028596,33,10726,24,4288,0.027712365,0.54973963,0.31474732,0.973260146,0.079595641,DB0047210028596_,2.530795943,-0.598310514,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,fluoxetine,DB00472
,41898,DB00668,10028596,36,10055,23,4280,0.153092314,0.666268939,0.38363663,1.179196531,0.288326692,DB0066810028596_,1.243661095,-0.406061878,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,epinephrine,DB00668
,41903,DB09153,10028596,33,7766,31,5668,0.31358028,0.776956912,0.460678389,1.313399977,0.481072526,DB0915310028596_,0.731737238,-0.252370385,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,sodium chloride,DB09153
,41904,DB00065,10035664,125,9339,71,4886,0.596398141,0.921102667,0.6814267,1.253270869,0.741811197,DB0006510035664_,0.298660519,-0.082183776,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,infliximab,DB00065
,41906,DB01050,10007882,83,18025,52,9319,0.276173572,0.825237237,0.575991378,1.191744775,0.439593202,DB0105010007882_,0.82190552,-0.192084374,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,41907,DB01050,10013950,97,18011,47,9324,0.79155379,1.06840706,0.745958707,1.54906995,0.887203509,DB0105010013950_,0.119680888,0.06616881,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,41908,DB00213,10061481,214,18681,129,13292,0.15201988,1.18033368,0.943173166,1.481910751,0.286779528,DB0021310061481_,1.249041553,0.165797178,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,41910,DB00480,10005734,102,67326,119,67543,0.281541606,0.859907254,0.653376629,1.13000683,0.445492305,DB0048010005734_,0.808575305,-0.150930739,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,41911,DB06643,10044055,282,52139,39,7476,0.932603732,1.036792791,0.739175225,1.490321405,0.973356195,DB0664310044055_,0.027005184,0.036132093,NA,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,41913,DB06643,10049088,48,52373,13,7502,0.050428879,0.528921803,0.281883979,1.064641463,0.12580164,DB0664310049088_,2.073048897,-0.636914678,NA,10049088,Osteopenia,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,41915,DB00722,10000059,320,25083,202,25830,4.30877073200886e-08,1.631309558,1.362348177,1.956936376,8.43620399931866e-07,DB0072210000059_,13.98556321,0.489383102,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,41917,DB00722,10022998,71,25332,54,25978,0.106890153,1.348331221,0.93272388,1.958886189,0.221473022,DB0072210022998_,1.507454493,0.298867695,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,41918,DB01238,10022998,68,5182,59,3443,0.144614588,0.765801546,0.530836589,1.10748996,0.276495877,DB0123810022998_,1.285559371,-0.266832221,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,41926,DB08828,10061428,61,701,80,1062,0.422511422,1.155078119,0.802462175,1.655982141,0.591524426,DB0882810061428_,0.525052302,0.144167977,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,vismodegib,DB08828
,41929,DB00295,10021015,78,14585,40,9562,0.220774164,1.278410462,0.861649532,1.92311778,0.374438567,DB0029510021015_,0.982327531,0.24561748,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,morphine,DB00295
,41931,DB00295,10045555,96,14567,91,9511,0.013036664,0.688816863,0.511008851,0.929012841,0.043982634,DB0029510045555_,3.123960394,-0.372779845,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,morphine,DB00295
,41932,DB00333,10045555,46,3025,69,3083,0.047852675,0.67949404,0.455826122,1.00478335,0.121080847,DB0033310045555_,2.1112968,-0.386406816,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,methadone,DB00333
,41936,DB00230,10002034,154,19520,64,8587,0.767858159,1.058525521,0.785013275,1.441557183,0.872615133,DB0023010002034_,0.136260676,0.056876921,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,pregabalin,DB00230
,41938,DB00620,10002034,74,4754,44,3088,0.704438759,1.092443536,0.740088939,1.629283174,0.822831302,DB0062010002034_,0.195004079,0.088416963,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,triamcinolone,DB00620
,41940,DB00287,10012735,39,1362,19,798,0.582259618,1.202503465,0.672993253,2.219347084,0.730429044,DB0028710012735_,0.314123187,0.184405605,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,travoprost,DB00287
,41941,DB00620,10012735,324,4504,162,2970,0.005406201,1.318782273,1.082312189,1.611755546,0.021768076,DB0062010012735_,3.827310808,0.27670879,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,triamcinolone,DB00620
,41942,DB01216,10012735,13,223,348,6767,0.644842466,1.133567419,0.588088847,2.004936484,0.780709787,DB0121610012735_,0.24755179,0.125369668,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,finasteride,DB01216
,41943,DB00287,10016256,57,1344,20,797,0.053683198,1.689695793,0.991071332,2.992649803,0.13188736,DB0028710016256_,2.025807054,0.524548509,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,travoprost,DB00287
,41944,DB00230,10061822,202,19472,70,8581,0.085712408,1.271646945,0.963198828,1.695846032,0.187863302,DB0023010061822_,1.672040696,0.240312868,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,41946,DB00425,10061822,67,12628,34,7450,0.535877224,1.162587812,0.757641941,1.813827156,0.692350898,DB0042510061822_,0.367662374,0.150648393,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,41947,DB00588,10061822,105,16419,35,8433,0.025270712,1.540811955,1.040930241,2.330558305,0.074100921,DB0058810061822_,2.602327323,0.432309521,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,41952,DB01234,10061822,273,31352,226,32662,0.011762347,1.258429864,1.050467873,1.50879415,0.040528715,DB0123410061822_,3.205744555,0.229864804,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,41953,DB01373,10061822,123,22597,34,7347,0.456973914,1.17620225,0.798084105,1.77579489,0.624317645,DB0137310061822_,0.471095993,0.162290816,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,41960,DB00531,10040753,42,7210,36,6480,0.909589083,1.0485526,0.654858275,1.68672391,0.95941208,DB0053110040753_,0.041434599,0.047410737,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,41962,DB00741,10040753,73,4021,22,3152,3.88658535123825e-05,2.60070892,1.591818171,4.411156395,0.000356016,DB0074110040753_,7.940533859,0.955784069,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,hydrocortisone,DB00741
,41971,DB00215,10000059,137,10966,39,5237,0.00347162,1.677559194,1.165835797,2.463830232,0.015223443,DB0021510000059_,4.184918749,0.517339876,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,41972,DB00222,10000059,46,3160,37,3091,0.439421063,1.216057216,0.769322908,1.934004157,0.60785636,DB0022210000059_,0.497816674,0.195613835,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,glimepiride,DB00222
,41974,DB13961,10000059,146,9311,67,6347,0.007465314,1.485386618,1.102852872,2.018139169,0.028187285,DB1396110000059_,3.568884294,0.395675087,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,41977,DB01050,10018836,45,18063,29,9342,0.390173347,0.802559736,0.491951269,1.328320989,0.560038577,DB0105010018836_,0.57974961,-0.219948989,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,41980,DB01609,10000087,45,1539,25,1318,0.089925379,1.541294449,0.91942102,2.638200408,0.195096249,DB0160910000087_,1.63426226,0.432622615,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,deferasirox,DB01609
,41981,DB01609,10016256,53,1531,45,1298,1,0.998534476,0.653573771,1.531262555,1,DB0160910016256_,0,-0.001466599,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,deferasirox,DB01609
,41983,DB01609,10065154,46,1538,35,1308,0.652468052,1.11767883,0.699786684,1.799136364,0.786738967,DB0160910065154_,0.239858766,0.111254061,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,deferasirox,DB01609
,41984,DB00196,10000880,13,5070,37,3248,6.88582090021037e-07,0.225126946,0.109622072,0.434144973,1.03012978009123e-05,DB0019610000880_,11.48324067,-1.491090832,male,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fluconazole,DB00196
,41987,DB00787,10000880,39,16961,69,17179,0.005077501,0.57249462,0.376092036,0.860434439,0.020709459,DB0078710000880_,3.877164731,-0.55775194,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acyclovir,DB00787
,41989,DB00196,10029366,35,5048,37,3248,0.039120095,0.608701466,0.371413364,0.995705002,0.103872713,DB0019610029366_,2.264589042,-0.496427335,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,fluconazole,DB00196
,41990,DB00437,10029366,44,6877,60,11486,0.311186415,1.22478919,0.80970672,1.839965528,0.478699299,DB0043710029366_,0.736682647,0.20276874,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,allopurinol,DB00437
,41992,DB00787,10029366,149,16851,137,17111,0.406529929,1.104363867,0.868898457,1.404509945,0.576138414,DB0078710029366_,0.551407344,0.099269484,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,acyclovir,DB00787
,41995,DB00328,10013700,184,576,61,754,2.39195279493053e-20,3.945160036,2.875460234,5.471653754,2.55060767605473e-18,DB0032810013700_,40.51020004,1.37248952,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,indomethacin,DB00328
,41996,DB06626,10019211,26,662,41,1411,0.234451178,1.351477212,0.786465614,2.284615191,0.391359934,DB0662610019211_,0.938127595,0.301198225,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,axitinib,DB06626
,41997,DB00169,10000496,85,38606,31,18144,0.272691767,1.288603088,0.844684434,2.012873786,0.435596396,DB0016910000496_,0.831039161,0.253558754,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,41999,DB00635,10000496,58,32995,29,23765,0.127462844,1.44051093,0.907016422,2.334307577,0.252030858,DB0063510000496_,1.378203747,0.364997863,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,42003,DB01373,10000496,40,22680,10,7371,0.514709077,1.299977992,0.63845146,2.916427086,0.674550799,DB0137310000496_,0.393708292,0.262347335,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,42008,DB00635,10028641,44,33009,65,23729,0.000200904,0.486615845,0.324014086,0.724762826,0.001446187,DB0063510028641_,6.538824678,-0.720280287,NA,10028641,Myopathy,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,42014,DB00169,10043607,283,38408,195,17980,5.10621684605367e-05,0.67938483,0.563609403,0.820309324,0.000450166,DB0016910043607_,7.705894773,-0.386567553,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,42016,DB00635,10043607,185,32868,141,23653,0.612767441,0.944219973,0.753806952,1.184791262,0.754601522,DB0063510043607_,0.281565454,-0.057396117,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,prednisone,DB00635
,42017,DB00678,10043607,118,15481,78,10646,0.82691025,1.040341587,0.774099826,1.404733095,0.908724875,DB0067810043607_,0.095712899,0.039549108,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,losartan,DB00678
,42018,DB00736,10043607,78,10513,50,5503,0.263704922,0.816602195,0.564362161,1.191022912,0.425566678,DB0073610043607_,0.854333639,-0.202603212,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,esomeprazole,DB00736
,42019,DB01373,10043607,181,22539,121,7260,2.17962266306785e-09,0.481830541,0.380044065,0.612638568,5.65282503194261e-08,DB0137310043607_,16.68852532,-0.730162801,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,calcium,DB01373
,42020,DB01611,10043607,43,11870,9,2352,0.851898771,0.946694714,0.454410648,2.211792062,0.927294854,DB0161110043607_,0.075483691,-0.05477861,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,hydroxychloroquine,DB01611
,42032,DB01118,10021097,149,2914,186,4523,0.059142342,1.243349705,0.990380487,1.558894697,0.141884404,DB0111810021097_,1.952742611,0.217809113,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,amiodarone,DB01118
,42035,DB00531,10028533,89,7163,113,6403,0.015615917,0.704067692,0.526096533,0.939848407,0.050880688,DB0053110028533_,2.978271834,-0.350880774,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyclophosphamide,DB00531
,42036,DB00997,10028533,96,5235,65,3449,0.871153858,0.973037632,0.700690744,1.358589307,0.943111644,DB0099710028533_,0.058570611,-0.027332521,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,doxorubicin,DB00997
,42040,DB05332,10022437,31,998,20,767,0.570097015,1.191118635,0.651839941,2.22349258,0.720856239,DB0533210022437_,0.327315553,0.174892895,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,romiplostim,DB05332
,42043,DB05332,10033425,32,997,20,767,0.570493075,1.230753298,0.676576705,2.289679476,0.721019857,DB0533210033425_,0.327088601,0.207626419,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,romiplostim,DB05332
,42045,DB05332,10035526,193,836,125,662,0.119368886,1.222505239,0.948584878,1.579390743,0.240374716,DB0533210035526_,1.425556256,0.200902228,NA,10035526,Platelet count abnormal,10022891,Investigations,Inv,romiplostim,DB05332
,42056,DB00182,10016322,185,5009,96,2756,0.703363697,1.060297285,0.820364427,1.377511342,0.82208701,DB0018210016322_,0.195909037,0.058549326,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,42057,DB00169,10006784,235,38456,66,18109,0.000147202,1.676681857,1.270248921,2.23931386,0.001108499,DB0016910006784_,6.804748611,0.516816755,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,42059,DB00451,10006784,226,47045,49,15370,0.009240616,1.506813527,1.101604655,2.097672529,0.033414445,DB0045110006784_,3.398766994,0.409997174,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,42060,DB00999,10006784,123,21307,35,12204,0.00017111,2.012835916,1.37189911,3.022481434,0.00126461,DB0099910006784_,6.672991819,0.699544631,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,42062,DB00999,10015150,182,21248,77,12162,0.027359124,1.352894207,1.029913041,1.791474538,0.078774737,DB0099910015150_,2.541162926,0.302246155,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,42063,DB00169,10037867,82,38609,35,18140,0.691922188,1.100760249,0.732241164,1.686023632,0.814253882,DB0016910037867_,0.205483067,0.096001077,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,42065,DB00451,10037867,90,47181,28,15391,0.914883665,1.048570546,0.679155055,1.66564542,0.961903265,DB0045110037867_,0.03884139,0.047427852,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,42066,DB00999,10037867,50,21380,26,12213,0.811435055,1.09853723,0.670518518,1.839566484,0.898631545,DB0099910037867_,0.106882178,0.093979504,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,42067,DB00169,10046735,373,38318,122,18053,0.000399381,1.440439512,1.17016041,1.783394562,0.002558864,DB0016910046735_,5.968192014,0.364948284,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,42068,DB00008,10018884,69,1456,60,1616,0.178337117,1.276270733,0.883009205,1.849046629,0.321784186,DB0000810018884_,1.133874189,0.243942336,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,peginterferon alfa-2a,DB00008
,42069,DB00008,10047942,91,1434,79,1597,0.115370398,1.282726884,0.930141611,1.771984734,0.234222066,DB0000810047942_,1.451485612,0.24898819,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,peginterferon alfa-2a,DB00008
,42070,DB00338,10014062,45,33629,29,22243,1,1.026347453,0.629374035,1.698147575,1,DB0033810014062_,0,0.026006338,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,42072,DB00338,10061422,52,33622,43,22229,0.294803209,0.799534989,0.523342527,1.227201892,0.460709435,DB0033810061422_,0.774987728,-0.223724984,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,42076,DB00390,10017955,91,4054,110,3191,0.003090359,0.651214134,0.485801802,0.871154495,0.013859423,DB0039010017955_,4.278789931,-0.42891676,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,digoxin,DB00390
,42077,DB01261,10017955,28,3753,38,3265,0.082614616,0.641077966,0.378005257,1.075135119,0.182734479,DB0126110017955_,1.699721116,-0.444604197,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,sitagliptin,DB01261
,42079,DB00203,10036653,144,13734,44,8894,5.63748318145554e-06,2.119314558,1.500794315,3.045602279,6.56395328569475e-05,DB0020310036653_,9.631332409,0.751092715,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,42080,DB00374,10036653,187,17529,44,5680,0.064323934,1.377108404,0.985566595,1.961388249,0.151230286,DB0037410036653_,1.888951529,0.319985942,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,42081,DB00203,10045555,45,13833,25,8913,0.624373382,1.159823142,0.695615312,1.975081728,0.764203597,DB0020310045555_,0.268921037,0.148267529,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,42082,DB00374,10045555,49,17667,20,5704,0.399553627,0.791019955,0.461139745,1.406125962,0.56942918,DB0037410045555_,0.563120858,-0.234432083,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,42085,DB00005,10013496,94,127988,33,42386,0.75862162,0.943332782,0.628290557,1.448608409,0.86535474,DB0000510013496_,0.144615752,-0.058336162,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,42090,DB00285,10013709,771,10180,239,3479,0.216073553,1.102451815,0.947291153,1.286563519,0.368698418,DB0028510013709_,0.997776266,0.097536622,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,42096,DB00563,10043882,49,46597,14,15334,0.770331277,1.151764691,0.62554684,2.259658922,0.874204063,DB0056310043882_,0.134441449,0.14129528,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,methotrexate,DB00563
,42097,DB09270,10012735,216,2898,133,2235,0.050595548,1.252458335,0.997118314,1.577733499,0.126099084,DB0927010012735_,2.070687302,0.225108288,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ubidecarenone,DB09270
,42098,DB00275,10047895,50,2010,41,1196,0.153148017,0.72573322,0.467430761,1.132266357,0.288390272,DB0027510047895_,1.243440603,-0.320572798,NA,10047895,Weight decreased,10022891,Investigations,Inv,olmesartan,DB00275
,42102,DB00381,10000125,35,29325,23,22864,0.597034403,1.186459243,0.681306678,2.103844423,0.74237425,DB0038110000125_,0.297901783,0.170973446,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,42105,DB00181,10008190,72,9784,41,5830,0.845878796,1.046407812,0.702420374,1.577464249,0.922531188,DB0018110008190_,0.080634096,0.045363167,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,42107,DB01175,10008190,77,10647,42,4850,0.371992943,0.835159698,0.565252154,1.249032156,0.541676549,DB0117510008190_,0.613086229,-0.180132317,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,42108,DB01238,10008190,43,5207,18,3484,0.114906322,1.598321125,0.900882808,2.949449851,0.233508266,DB0123810008190_,1.454537803,0.468953782,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,42110,DB01175,10002855,352,10372,133,4759,0.065632419,1.214313067,0.988860725,1.498407601,0.153530738,DB0117510002855_,1.873854485,0.19417854,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,42112,DB00437,10055798,44,6877,77,11469,0.850814287,0.952989107,0.641717626,1.399800986,0.926372712,DB0043710055798_,0.076478629,-0.048151805,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,allopurinol,DB00437
,42113,DB00787,10055798,41,16959,47,17201,0.594667832,0.88479208,0.567194802,1.375270728,0.740481451,DB0078710055798_,0.300454695,-0.122402599,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,acyclovir,DB00787
,42114,DB01015,10055798,38,9849,41,9340,0.575072868,0.878936952,0.549603164,1.402502711,0.724646567,DB0101510055798_,0.322071237,-0.129042111,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,sulfamethoxazole,DB01015
,42115,DB13961,10055798,34,9423,34,6380,0.109049565,0.677099719,0.407865678,1.123989675,0.224616879,DB1396110055798_,1.493359088,-0.389936721,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,fish oil,DB13961
,42119,DB00295,10038678,42,14621,88,9514,1.02420282897935e-10,0.31058007,0.209514895,0.453954572,3.33676290759771e-09,DB0029510038678_,19.51826469,-1.169313537,male,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,42120,DB00295,10039897,48,14615,61,9541,0.000555118,0.51370027,0.344130694,0.763019378,0.003365923,DB0029510039897_,5.694052974,-0.666115317,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,morphine,DB00295
,42141,DB00635,10006473,60,32993,53,23741,0.294243122,0.814623478,0.553314056,1.20225216,0.460056283,DB0063510006473_,0.776406444,-0.205029263,NA,10006473,Bronchopulmonary aspergillosis,10021881,Infections and infestations,Infec,prednisone,DB00635
,42145,DB00864,10016256,163,6706,181,8211,0.380801946,1.102651916,0.884510654,1.373644983,0.550828448,DB0086410016256_,0.596331865,0.097718111,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,42148,DB00635,10022694,43,33010,37,23757,0.429541619,0.836404224,0.526138717,1.335397611,0.597998012,DB0063510022694_,0.51416785,-0.178643261,NA,10022694,Intestinal perforation,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,42153,DB00544,10033553,36,2399,25,2628,0.093326369,1.577302892,0.917970723,2.750006479,0.200661235,DB0054410033553_,1.60613719,0.455716358,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,fluorouracil,DB00544
,42159,DB00635,10041823,30,33023,45,23749,0.00210702,0.479443989,0.291559346,0.778190766,0.010153638,DB0063510041823_,4.589923229,-0.735128203,NA,10041823,Squamous cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,42169,DB00588,10000059,205,16319,91,8377,0.266437149,1.156378646,0.897761407,1.499215175,0.428585445,DB0058810000059_,0.847265155,0.145293265,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,42170,DB00338,10022052,123,33551,26,22246,6.25796970469114e-09,3.13665796,2.040914194,4.992779005,1.47459196492879e-07,DB0033810022052_,15.72971433,1.143157889,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,42171,DB00722,10022052,96,25307,33,25999,8.5079501757366e-09,2.988679674,1.99262747,4.585459878,1.94347670831424e-07,DB0072210022052_,15.45361716,1.094831709,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,42172,DB00999,10022052,78,21352,20,12219,0.000724592,2.231783223,1.350895396,3.854477525,0.004212763,DB0099910022052_,5.469636541,0.802800917,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,42173,DB00588,10025482,660,15864,183,8285,3.98549572478913e-15,1.883486306,1.593010947,2.235907882,2.48243495559436e-13,DB0058810025482_,29.02436629,0.633124477,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,42174,DB00512,10013709,245,4492,361,4737,9.25603472289097e-05,0.715713137,0.602866648,0.848587385,0.000746991,DB0051210013709_,7.199457816,-0.334475839,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,42175,DB01212,10013709,89,1930,115,1826,0.031197807,0.732271548,0.54473312,0.981810498,0.087335252,DB0121210013709_,2.438001098,-0.311603867,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ceftriaxone,DB01212
,42176,DB09153,10013709,162,7637,94,5605,0.073858961,1.264830445,0.972559713,1.652694325,0.167961481,DB0915310013709_,1.784020604,0.234938078,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,42177,DB00661,10019211,159,3369,45,1550,0.004193611,1.625465579,1.153835532,2.329455133,0.017751681,DB0066110019211_,4.031275049,0.485794285,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,verapamil,DB00661
,42180,DB00563,10005557,106,46540,51,15297,0.032679354,0.683154086,0.484486664,0.974257079,0.090590258,DB0056310005557_,2.401408604,-0.381034843,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,methotrexate,DB00563
,42182,DB00563,10041349,173,46473,60,15288,0.70439968,0.948512868,0.70289135,1.295250138,0.822821279,DB0056310041349_,0.195016259,-0.052859923,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,42191,DB01137,10016288,146,7626,187,5406,1.3960039016906e-07,0.553504311,0.441378078,0.69301536,2.45938086836041e-06,DB0113710016288_,12.91560092,-0.591485739,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,levofloxacin,DB01137
,42192,DB01137,10021789,102,7670,78,5515,0.704022168,0.940290368,0.691835214,1.282096967,0.822564017,DB0113710021789_,0.195328968,-0.061566549,NA,10021789,Infection,10021881,Infections and infestations,Infec,levofloxacin,DB01137
,42193,DB01137,10029331,199,7573,163,5430,0.214648248,0.875392379,0.705917055,1.086802796,0.367069128,DB0113710029331_,1.002205089,-0.13308306,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,42202,DB00722,10069326,45,25358,63,25969,0.123021629,0.731503321,0.487371614,1.090002588,0.245768908,DB0072210069326_,1.403363585,-0.312653519,NA,10069326,Product substitution issue,10077536,Product issues,Prod,lisinopril,DB00722
,42204,DB01015,10000087,84,9803,67,9314,0.289542802,1.191179852,0.852624519,1.669684564,0.454705087,DB0101510000087_,0.78810623,0.174944288,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,42206,DB00497,10005364,49,19218,44,16331,0.835216428,0.946314057,0.616561134,1.456348325,0.91469788,DB0049710005364_,0.089161454,-0.055180781,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,oxycodone,DB00497
,42207,DB01015,10005364,24,9863,31,9350,0.281024847,0.73394095,0.41185546,1.293069977,0.444956016,DB0101510005364_,0.809779841,-0.309326704,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,42212,DB00879,10012735,28,1749,150,3562,4.94655337002265e-07,0.380219677,0.24344736,0.574754188,7.6798674147103e-06,DB0087910012735_,11.77690827,-0.967006097,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,emtricitabine,DB00879
,42234,DB00497,10024690,31,19236,21,16354,0.487024505,1.255013594,0.698146765,2.298884519,0.6509096,DB0049710024690_,0.429384509,0.227146404,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,oxycodone,DB00497
,42239,DB01015,10025197,32,9855,34,9347,0.711781779,0.892666997,0.532820369,1.492274348,0.828334804,DB0101510025197_,0.188337853,-0.113541671,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,sulfamethoxazole,DB01015
,42245,DB00879,10028813,82,1695,183,3529,0.638041008,0.932927936,0.705376345,1.225407676,0.775273465,DB0087910028813_,0.254539454,-0.06942732,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,emtricitabine,DB00879
,42246,DB00497,10033645,73,19194,64,16311,0.864018045,0.969290205,0.682951445,1.37871255,0.937432742,DB0049710033645_,0.064610266,-0.031191223,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,42248,DB01015,10033645,38,9849,40,9341,0.651909288,0.901005385,0.561936328,1.442456175,0.78617341,DB0101510033645_,0.240577888,-0.104244044,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,42250,DB00497,10037087,281,18986,161,16214,5.25233042719139e-05,1.490497415,1.222210112,1.822712925,0.000460729,DB0049710037087_,7.682700103,0.3991099,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,42252,DB00879,10037844,35,1742,103,3609,0.080054215,0.704037177,0.463443616,1.047262973,0.178490547,DB0087910037844_,1.72321964,-0.350924116,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,emtricitabine,DB00879
,42257,DB00879,10047700,38,1739,74,3638,0.759664214,1.074257941,0.703586925,1.616832737,0.866224492,DB0087910047700_,0.143611175,0.071630136,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,emtricitabine,DB00879
,42264,DB01015,10054889,23,9864,44,9337,0.006660918,0.494820786,0.284969543,0.83811461,0.025762539,DB0101510054889_,3.658833804,-0.70355963,NA,10054889,Transaminases increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,42270,DB00879,10065042,14,1763,77,3635,0.000269301,0.374932291,0.195313879,0.670196716,0.001846985,DB0087910065042_,6.294200932,-0.981009827,NA,10065042,Immune reconstitution inflammatory syndrome,10021428,Immune system disorders,Immun,emtricitabine,DB00879
,42272,DB08930,10065042,11,446,56,811,0.000927554,0.357414809,0.167098525,0.698415778,0.005177548,DB0893010065042_,5.263423702,-1.028858242,male,10065042,Immune reconstitution inflammatory syndrome,10021428,Immune system disorders,Immun,dolutegravir,DB08930
,42276,DB00285,10001497,92,10859,36,3682,0.475320504,0.866549571,0.582329231,1.314306197,0.640954185,DB0028510001497_,0.444797299,-0.143235963,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,42277,DB00285,10002368,55,10896,20,3698,0.790582096,0.933322371,0.549639352,1.646398772,0.886565478,DB0028510002368_,0.120400295,-0.069004617,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,42285,DB00722,10007882,162,25241,148,25884,0.332819535,1.122475652,0.891995432,1.41333246,0.501816181,DB0072210007882_,0.6895214,0.11553665,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,lisinopril,DB00722
,42287,DB01104,10007882,86,15377,31,7255,0.23305045,1.308925773,0.858061606,2.044461761,0.389590809,DB0110410007882_,0.942658298,0.26920678,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,sertraline,DB01104
,42289,DB01373,10007882,125,22595,43,7338,0.719908984,0.944072717,0.661959153,1.369522912,0.834674324,DB0137310007882_,0.180713661,-0.057552085,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,calcium,DB01373
,42293,DB01104,10024264,79,15384,43,7243,0.437955495,0.864998387,0.588621087,1.286387185,0.606409284,DB0110410024264_,0.500200136,-0.145027637,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,42304,DB00169,10048294,108,38583,69,18106,0.05234337,0.734498339,0.537769401,1.009045871,0.129424343,DB0016910048294_,2.044658789,-0.308567545,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,42305,DB00334,10048294,51,2798,60,2752,0.388519139,0.836053393,0.561852294,1.239953564,0.558504853,DB0033410048294_,0.582491971,-0.179062801,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,42306,DB00722,10048294,111,25292,131,25901,0.274211638,0.867733861,0.66729909,1.126697955,0.43734431,DB0072210048294_,0.8270345,-0.141870223,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,42309,DB01373,10048294,51,22669,19,7362,0.580431373,0.871749674,0.50549067,1.56462256,0.728953804,DB0137310048294_,0.316144919,-0.137252967,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,calcium,DB01373
,42310,DB00169,10070863,83,38608,60,18115,0.01184651,0.649061961,0.459831684,0.920904951,0.040762602,DB0016910070863_,3.199990224,-0.432227095,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,42311,DB00909,10070863,35,785,18,463,0.771633788,1.146762519,0.62379158,2.176985693,0.875014307,DB0090910070863_,0.133515042,0.136942771,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,zonisamide,DB00909
,42312,DB01098,10070863,63,8086,36,7173,0.042801888,1.5523569,1.013506786,2.41037664,0.111313707,DB0109810070863_,2.195402874,0.439774357,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,rosuvastatin,DB01098
,42313,DB01202,10070863,247,6467,163,5555,0.010156401,1.301609551,1.060116402,1.60154897,0.036007688,DB0120210070863_,3.324022798,0.263601615,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,levetiracetam,DB01202
,42314,DB01373,10070863,41,22679,31,7350,0.00052874,0.428644248,0.262138278,0.707504399,0.003231129,DB0137310070863_,5.734923558,-0.847127963,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,42323,DB00864,10020635,39,6830,45,8347,0.826367157,1.059126628,0.670881919,1.665588361,0.908355911,DB0086410020635_,0.096119005,0.057444633,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,tacrolimus,DB00864
,42326,DB14726,10012735,74,1943,62,2786,0.002561981,1.711148048,1.19815659,2.450813149,0.01188942,DB1472610012735_,4.432106326,0.537164518,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dabigatran,DB14726
,42327,DB00722,10008469,144,25259,92,25940,0.000403747,1.607391244,1.228159783,2.112685853,0.002583055,DB0072210008469_,5.958782532,0.474612519,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,42329,DB00722,10016825,127,25276,72,25960,4.67402054476514e-05,1.81158876,1.345476003,2.455198919,0.000417099,DB0072210016825_,7.782185981,0.594204228,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,lisinopril,DB00722
,42330,DB00722,10024570,122,25281,207,25825,6.92970151164568e-06,0.60206341,0.477010017,0.757170965,7.8800434451052e-05,DB0072210024570_,9.448592048,-0.507392506,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,42332,DB00722,10034829,36,25367,54,25978,0.090846114,0.68273232,0.434796461,1.060586278,0.196582703,DB0072210034829_,1.626672055,-0.381652414,NA,10034829,Pharyngeal oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,42334,DB05259,10042682,68,11202,16,2712,1,1.028927541,0.589222835,1.903974371,1,DB0525910042682_,0,0.028517037,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,42336,DB05259,10047700,219,11051,41,2687,0.133507018,1.298725439,0.924206004,1.865156597,0.260636467,DB0525910047700_,1.344628688,0.261383352,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,glatiramer,DB05259
,42337,DB00394,10012735,61,1578,35,759,0.437347756,0.838369793,0.539079648,1.321531463,0.605769393,DB0039410012735_,0.501255904,-0.176295995,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,beclomethasone dipropionate,DB00394
,42338,DB00489,10012735,56,1027,49,1085,0.368901869,1.207295011,0.799863923,1.827359972,0.538525033,DB0048910012735_,0.618921296,0.188382329,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sotalol,DB00489
,42344,DB00252,10013710,88,2144,95,1813,0.111443102,0.783357862,0.575365734,1.065656577,0.228208315,DB0025210013710_,1.477496404,-0.244165648,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,phenytoin,DB00252
,42351,DB00333,10033295,97,2974,127,3025,0.066432643,0.776910819,0.587258113,1.025204606,0.154940729,DB0033310033295_,1.864712629,-0.252429712,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,methadone,DB00333
,42356,DB00281,10047513,92,11366,47,5624,0.856720278,0.968594418,0.673345554,1.409507025,0.931225395,DB0028110047513_,0.071253931,-0.031909312,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,lidocaine,DB00281
,42358,DB00668,10047513,34,10057,20,4283,0.296526404,0.723993513,0.4044482,1.329026319,0.462398013,DB0066810047513_,0.771329258,-0.322972847,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,epinephrine,DB00668
,42361,DB00758,10055798,126,8174,201,9873,0.015837727,0.757174694,0.599920652,0.952694159,0.05144072,DB0075810055798_,2.967325204,-0.27816128,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,clopidogrel,DB00758
,42377,DB00863,10010305,115,10558,68,5772,0.640994886,0.924562528,0.677921598,1.269208768,0.777882711,DB0086310010305_,0.251179524,-0.078434596,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ranitidine,DB00863
,42378,DB01109,10010305,31,4381,38,4232,0.336159964,0.788067851,0.473186449,1.303330628,0.505257999,DB0110910010305_,0.682686091,-0.238171088,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,heparin,DB01109
,42379,DB11089,10010305,161,10014,180,8227,0.00506769,0.734849295,0.589149598,0.915920194,0.020683885,DB1108910010305_,3.878400385,-0.308089842,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,docusate,DB11089
,42381,DB00186,10013395,41,16860,44,9964,0.006734146,0.550727428,0.350664567,0.863197822,0.025976963,DB0018610013395_,3.650545188,-0.596515277,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,42383,DB00497,10013395,62,19205,41,16334,0.235028619,1.286122946,0.852560358,1.958648234,0.39204996,DB0049710013395_,0.936365999,0.251632225,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,42388,DB00186,10013496,58,16843,27,9981,0.314338102,1.272974653,0.792693659,2.092235435,0.481939863,DB0018610013496_,0.729935939,0.241356408,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,42389,DB00193,10013496,51,19269,18,8684,0.43512504,1.276860209,0.732956203,2.323901674,0.603565354,DB0019310013496_,0.504900953,0.244404103,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,42392,DB00186,10013754,96,16805,54,9954,0.799797001,1.053022344,0.746060413,1.499707043,0.891761512,DB0018610013754_,0.114556546,0.051664452,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,42397,DB00186,10013887,62,16839,37,9971,1,0.992228908,0.649461997,1.534984912,1,DB0018610013887_,0,-0.007801444,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,42398,DB00193,10013887,37,19283,22,8680,0.32444464,0.757034182,0.434741612,1.348148709,0.492906821,DB0019310013887_,0.707435126,-0.278346872,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,42399,DB00497,10013887,43,19224,28,16347,0.285556037,1.30587289,0.792466713,2.183873784,0.450165857,DB0049710013887_,0.798139192,0.266871698,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,42402,DB11089,10013887,40,10135,32,8375,0.906265058,1.032933403,0.632081356,1.700464706,0.958151532,DB1108910013887_,0.042749339,0.032402718,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,docusate,DB11089
,42404,DB00186,10019075,31,16870,19,9989,0.884782449,0.966059452,0.528437587,1.810980666,0.95196507,DB0018610019075_,0.049226936,-0.034529902,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,42411,DB00186,10020642,139,16762,77,9931,0.671845092,1.069530386,0.802910485,1.433598926,0.800827851,DB0018610020642_,0.222109273,0.067219661,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,42412,DB00193,10020642,173,19147,73,8629,0.678245388,1.068025526,0.80685833,1.425796343,0.805061303,DB0019310020642_,0.216836852,0.065811641,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,42413,DB00863,10020642,97,10576,46,5794,0.482300361,1.155211115,0.804034112,1.68108663,0.646749738,DB0086310020642_,0.435795863,0.144283111,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,42414,DB01109,10020642,32,4380,50,4220,0.034861818,0.616659346,0.382030214,0.98240911,0.095155024,DB0110910020642_,2.352247888,-0.483438521,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,heparin,DB01109
,42416,DB00863,10022437,195,10478,88,5752,0.132758578,1.216391162,0.938948472,1.586361153,0.259652386,DB0086310022437_,1.34841152,0.195888411,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ranitidine,DB00863
,42417,DB01109,10022437,31,4381,19,4251,0.120324746,1.58307381,0.864963767,2.970885131,0.241806371,DB0110910022437_,1.419617992,0.459368406,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,heparin,DB01109
,42419,DB00193,10022998,76,19244,25,8677,0.196096837,1.370750562,0.861634239,2.250246094,0.344373166,DB0019310022998_,1.066029425,0.315358445,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,42420,DB00316,10022998,191,65283,110,36843,0.857151624,0.979921056,0.770739219,1.251080141,0.931501651,DB0031610022998_,0.070957316,-0.020283266,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,42426,DB01109,10024378,19,4393,32,4238,0.066884298,0.572840758,0.306262677,1.043686212,0.155731577,DB0110910024378_,1.859621417,-0.557147509,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,heparin,DB01109
,42435,DB01109,10033371,123,4289,73,4197,0.00084537,1.648686383,1.22020499,2.24106504,0.004791491,DB0110910033371_,5.34091373,0.499978839,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,42437,DB00186,10040108,54,16847,53,9955,0.009122586,0.602094521,0.404078582,0.897440478,0.033084947,DB0018610040108_,3.408676887,-0.507340834,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,42438,DB00193,10040108,163,19157,78,8624,0.674988358,0.940753242,0.713050604,1.250115904,0.802945891,DB0019310040108_,0.21946795,-0.061074404,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,42439,DB00497,10040108,49,19218,82,16293,0.000143337,0.506626954,0.347920861,0.730951074,0.001084987,DB0049710040108_,6.826187389,-0.679980337,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,42442,DB11089,10040108,10,10165,46,8361,1.78017028682443e-08,0.178843503,0.080414319,0.359494886,3.77353032170807e-07,DB1108910040108_,14.79008466,-1.721244138,male,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,docusate,DB11089
,42444,DB00193,10046543,48,19272,30,8672,0.177242355,0.719962428,0.446631965,1.177741462,0.320336597,DB0019310046543_,1.13838297,-0.328556251,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,tramadol,DB00193
,42447,DB11089,10046543,45,10130,36,8371,0.911373209,1.032949666,0.650947342,1.649681545,0.960195795,DB1108910046543_,0.040618062,0.032418463,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,docusate,DB11089
,42448,DB00682,10022000,307,19152,143,16221,1.60953825118031e-09,1.818266713,1.484475626,2.235792597,4.29509775962176e-08,DB0068210022000_,16.96320643,0.597883692,NA,10022000,Influenza,10021881,Infections and infestations,Infec,warfarin,DB00682
,42449,DB08932,10022000,448,18995,112,6485,0.003168695,1.365580408,1.105593863,1.698496233,0.014146777,DB0893210022000_,4.258268429,0.311579545,NA,10022000,Influenza,10021881,Infections and infestations,Infec,macitentan,DB08932
,42450,DB08932,10037423,499,18944,140,6457,0.047562344,1.214858522,1.002987986,1.479164048,0.120504719,DB0893210037423_,2.116066366,0.194627627,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,42455,DB06700,10013709,239,1986,59,559,0.414917854,1.140138748,0.840028543,1.566984457,0.584136246,DB0670010013709_,0.537621025,0.131149964,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,desvenlafaxine,DB06700
,42456,DB00252,10013968,45,2187,24,1884,0.067303471,1.615040312,0.959129041,2.782677183,0.156500478,DB0025210013968_,1.854696214,0.479359917,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,phenytoin,DB00252
,42460,DB00273,10022000,59,8422,12,2181,0.555381591,1.273211953,0.675673833,2.607225751,0.708750207,DB0027310022000_,0.344252133,0.241542805,NA,10022000,Influenza,10021881,Infections and infestations,Infec,topiramate,DB00273
,42465,DB01202,10022000,44,6670,30,5688,0.352635599,1.250711068,0.767619961,2.063383398,0.522389986,DB0120210022000_,0.649340871,0.223712244,NA,10022000,Influenza,10021881,Infections and infestations,Infec,levetiracetam,DB01202
,42473,DB00121,10003549,141,4082,16,452,0.89229262,0.975810202,0.573905628,1.77010559,0.955096839,DB0012110003549_,0.045942542,-0.024487176,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,42475,DB00335,10013952,59,8407,24,5441,0.055645737,1.590978862,0.973238954,2.677899941,0.135444905,DB0033510013952_,1.999190325,0.464349463,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atenolol,DB00335
,42476,DB00433,10013952,30,7626,22,5998,0.888994439,1.072539692,0.597614619,1.953488655,0.953939248,DB0043310013952_,0.047155291,0.07002938,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,42477,DB00788,10013952,36,9320,16,5045,0.563004559,1.217893626,0.658100582,2.353133775,0.715096999,DB0078810013952_,0.335337083,0.197122831,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,naproxen,DB00788
,42478,DB00836,10013952,32,5503,19,4056,0.481211828,1.241323598,0.681407975,2.321453468,0.645866672,DB0083610013952_,0.437162186,0.216178228,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loperamide,DB00836
,42480,DB00381,10023126,21,29339,42,22845,0.000311761,0.38933371,0.218979451,0.672617166,0.002082817,DB0038110023126_,6.174034209,-0.943318438,NA,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,amlodipine,DB00381
,42486,DB00121,10047895,111,4112,21,447,0.026671083,0.574674546,0.353894079,0.974975261,0.077271912,DB0012110047895_,2.560424754,-0.553951405,NA,10047895,Weight decreased,10022891,Investigations,Inv,biotin,DB00121
,42487,DB00836,10047895,173,5362,125,3950,0.905264469,1.019544267,0.80218179,1.298702999,0.957775933,DB0083610047895_,0.043141419,0.01935573,NA,10047895,Weight decreased,10022891,Investigations,Inv,loperamide,DB00836
,42488,DB00121,10061428,84,4139,18,450,0.017513496,0.507453422,0.299081092,0.905925667,0.055691053,DB0012110061428_,2.887935776,-0.678350352,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,biotin,DB00121
,42489,DB00761,10061428,369,14938,187,8438,0.245299771,1.11464423,0.930310791,1.339059542,0.404105448,DB0076110061428_,0.906079426,0.108535278,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,42490,DB00788,10061428,126,9230,81,4980,0.240506585,0.839312115,0.628440451,1.126186698,0.398456751,DB0078810061428_,0.920156317,-0.175172633,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,naproxen,DB00788
,42491,DB00836,10061428,178,5357,101,3974,0.036467581,1.307352267,1.014714009,1.691917492,0.098509877,DB0083610061428_,2.317598465,0.268003921,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,loperamide,DB00836
,42492,DB08881,10011906,45,578,64,747,0.688034865,0.908799737,0.596801581,1.374206226,0.81191481,DB0888110011906_,0.208359858,-0.095630521,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,vemurafenib,DB08881
,42495,DB00437,10000059,80,6841,114,11432,0.296619713,1.172684165,0.868462899,1.577141362,0.462434706,DB0043710000059_,0.771249907,0.15929528,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,42496,DB00472,10000059,97,10662,28,4284,0.136121362,1.391873419,0.904504101,2.205559818,0.264301933,DB0047210000059_,1.330663143,0.330650623,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,42497,DB01136,10000059,122,9762,94,11021,0.006029848,1.465219195,1.108848846,1.94121304,0.02375696,DB0113610000059_,3.739879749,0.382004853,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,42498,DB08827,10000059,63,1099,36,546,0.512038759,0.86950486,0.560476499,1.366466215,0.672308247,DB0882710000059_,0.397038343,-0.139831356,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,lomitapide,DB08827
,42501,DB00338,10001551,112,33562,87,22185,0.276623483,0.850969112,0.636994481,1.140000232,0.440055058,DB0033810001551_,0.820855428,-0.161379448,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,omeprazole,DB00338
,42502,DB00437,10001551,35,6886,39,11507,0.091769758,1.499589903,0.921454207,2.432289264,0.198075881,DB0043710001551_,1.619105084,0.405191673,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,allopurinol,DB00437
,42503,DB00472,10001551,40,10719,16,4296,1,1.001959099,0.548038819,1.918665,1,DB0047210001551_,0,0.001957182,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,fluoxetine,DB00472
,42504,DB00999,10001551,66,21364,30,12209,0.339293202,1.257269231,0.804443112,2.006802102,0.508363324,DB0099910001551_,0.676558882,0.228942092,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,42505,DB01136,10001551,21,9863,31,11084,0.404265916,0.761292315,0.415486983,1.368987949,0.573982045,DB0113610001551_,0.555157163,-0.272737875,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,carvedilol,DB01136
,42511,DB00338,10003481,111,33563,83,22189,0.419187852,0.884145871,0.658941987,1.190232757,0.588272967,DB0033810003481_,0.530564208,-0.123133217,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,omeprazole,DB00338
,42512,DB00437,10003481,35,6886,49,11497,0.430871751,1.192563783,0.749273905,1.880211325,0.599310172,DB0043710003481_,0.511975998,0.176105429,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,allopurinol,DB00437
,42513,DB00472,10003481,37,10722,14,4298,1,1.059406195,0.558738485,2.123660946,1,DB0047210003481_,0,0.057708558,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,fluoxetine,DB00472
,42514,DB00999,10003481,65,21365,24,12215,0.076937872,1.548414664,0.955650104,2.587857905,0.173070398,DB0099910003481_,1.754056841,0.43723161,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,42515,DB01136,10003481,23,9861,34,11081,0.353076996,0.760174529,0.427258144,1.329733949,0.522808147,DB0113610003481_,0.648540713,-0.274207228,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,carvedilol,DB01136
,42521,DB00169,10016766,185,38506,84,18091,0.844221635,1.034701605,0.794799064,1.356488581,0.921259006,DB0016910016766_,0.082014059,0.034113081,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,42522,DB00338,10016766,155,33519,106,22166,0.800079845,0.966970867,0.750018611,1.250730627,0.891935108,DB0033810016766_,0.114361898,-0.033586911,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,42523,DB00437,10016766,27,6894,41,11505,0.707936747,1.098986207,0.649492622,1.831960053,0.825491852,DB0043710016766_,0.191775886,0.094388125,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,42525,DB01136,10016766,50,9834,49,11066,0.545108573,1.1482356,0.757887408,1.740458668,0.699942788,DB0113610016766_,0.356756679,0.138226503,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,42528,DB08827,10016766,76,1086,43,539,0.545820228,0.877284022,0.586647569,1.325937008,0.700533713,DB0882710016766_,0.355912787,-0.130924482,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,lomitapide,DB08827
,42531,DB00338,10024690,49,33625,42,22230,0.238544688,0.771315324,0.500124562,1.194185139,0.396267908,DB0033810024690_,0.925664761,-0.259658008,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,omeprazole,DB00338
,42539,DB05676,10003239,1176,45953,514,24815,6.95833889326121e-05,1.235546553,1.111571854,1.374676036,0.000584065,DB0567610003239_,7.445498373,0.211513426,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,42542,DB05676,10027175,319,46810,238,25091,0.000145683,0.718476726,0.605063282,0.854007325,0.00109926,DB0567610027175_,6.813117732,-0.330621966,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,42543,DB05676,10033425,558,46571,191,25138,2.63019487452847e-08,1.576933311,1.334631044,1.869771701,5.37594652231577e-07,DB0567610033425_,14.436161,0.455482018,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,42544,DB05676,10037087,867,46262,412,24917,0.038370412,1.133441888,1.005764697,1.278911278,0.102376925,DB0567610037087_,2.27909393,0.125258922,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,42550,DB05676,10074859,117,47012,103,25226,0.000291044,0.609500527,0.463504754,0.802592051,0.00196787,DB0567610074859_,6.230803781,-0.495115465,NA,10074859,Faeces soft,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,42554,DB00193,10017577,306,19014,90,8612,0.000240532,1.5399382,1.211836464,1.973104159,0.001680814,DB0019310017577_,6.388477079,0.431742286,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,42559,DB00338,10053483,43,33631,11,22261,0.003207617,2.587448292,1.311816724,5.565590852,0.014285365,DB0033810053483_,4.248519706,0.950672175,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,42564,DB00108,10008190,101,10093,36,3259,0.617554426,0.905901048,0.612234124,1.367739451,0.75852421,DB0010810008190_,0.276380562,-0.098825198,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,42567,DB00476,10022004,169,17088,41,6136,0.02256852,1.480046563,1.045403097,2.138971127,0.067888939,DB0047610022004_,2.689882155,0.392073549,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,42569,DB00497,10016970,37,19230,15,16360,0.017090514,2.098439058,1.123793208,4.117398743,0.054613599,DB0049710016970_,2.907472361,0.741193763,NA,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,42570,DB06228,10053762,393,15519,364,15712,0.239146379,1.093079366,0.943748527,1.266339529,0.396870895,DB0622810053762_,0.924144252,0.08899882,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,42581,DB08932,10061225,88,19355,16,6581,0.017587466,1.870149351,1.088960437,3.416406233,0.055892461,DB0893210061225_,2.884325769,0.626018295,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,42583,DB14500,10003988,179,7630,57,4016,0.000848265,1.652838345,1.217162072,2.273635902,0.004805831,DB1450010003988_,5.337925373,0.502494019,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,42584,DB00215,10028810,138,10965,41,5235,0.007758777,1.606910825,1.12464055,2.340138541,0.029061555,DB0021510028810_,3.538339109,0.474313593,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,citalopram,DB00215
,42585,DB00404,10028810,225,19667,74,9788,0.00196599,1.513216234,1.15743218,1.997648026,0.009599862,DB0040410028810_,4.646006589,0.414237342,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,alprazolam,DB00404
,42586,DB00425,10028810,117,12578,56,7428,0.206705061,1.233786054,0.888658286,1.730725495,0.357320872,DB0042510028810_,1.0291211,0.210087535,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,zolpidem,DB00425
,42587,DB00497,10028810,227,19040,97,16278,4.30203094080726e-09,2.000650655,1.569030848,2.567072755,1.04848292331125e-07,DB0049710028810_,16.07075137,0.693472455,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,oxycodone,DB00497
,42588,DB00563,10028810,600,46046,124,15224,7.4192274181433e-07,1.599733521,1.315258046,1.958802452,1.09960187587199e-05,DB0056310028810_,11.41797728,0.469837066,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,methotrexate,DB00563
,42589,DB00813,10028810,67,10505,25,10143,2.28704184853919e-05,2.587728561,1.61113937,4.27935941,0.000224017,DB0081310028810_,8.40378973,0.950780487,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,fentanyl,DB00813
,42591,DB14500,10028810,191,7618,60,4013,0.000357087,1.676844886,1.245062346,2.286216676,0.002332008,DB1450010028810_,6.061025756,0.516913984,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,potassium,DB14500
,42592,DB00005,10061258,97,127985,46,42373,0.052368685,0.698144296,0.486599143,1.014570491,0.12946867,DB0000510061258_,2.044316359,-0.359329469,NA,10061258,Joint lock,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,42603,DB00843,10006093,27,2167,40,2133,0.110048909,0.6644748,0.390615782,1.114411191,0.226136874,DB0084310006093_,1.486614826,-0.408758325,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,donepezil,DB00843
,42604,DB00843,10020642,25,2169,30,2143,0.499915383,0.82338207,0.462620338,1.453686933,0.661587412,DB0084310020642_,0.413113162,-0.194334946,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,donepezil,DB00843
,42609,DB00787,10024264,53,16947,49,17199,0.691913943,1.097701077,0.729753278,1.654096459,0.814253882,DB0078710024264_,0.205483067,0.093218063,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,42610,DB00787,10029350,54,16946,127,17121,8.34245000482286e-08,0.429571241,0.306245964,0.595569009,1.53504584092943e-06,DB0078710029350_,13.38695031,-0.844967681,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,42612,DB00787,10033775,167,16833,145,17103,0.172534296,1.170191077,0.930138256,1.47359054,0.31418227,DB0078710033775_,1.157781983,0.157167049,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,42621,DB13867,10001760,55,4495,6,2548,5.34004077254876e-06,5.194584278,2.236067663,14.7906583,6.26620409403768e-05,DB1386710001760_,9.677754701,1.647616598,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone,DB13867
,42622,DB00169,10023644,93,38598,33,18142,0.180926069,1.32465822,0.881410224,2.035594961,0.325038734,DB0016910023644_,1.123810922,0.281154479,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,42623,DB00451,10023644,106,47165,22,15397,0.051184815,1.572838497,0.986401837,2.61660856,0.127272053,DB0045110023644_,2.061428334,0.452881947,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,levothyroxine,DB00451
,42624,DB00641,10023644,39,14085,20,12455,0.050017796,1.724294264,0.980939329,3.122212876,0.125026652,DB0064110023644_,2.079228346,0.544817845,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,simvastatin,DB00641
,42626,DB01373,10023644,55,22665,14,7367,0.484671186,1.276918093,0.700039522,2.48802239,0.648803551,DB0137310023644_,0.432625304,0.244449434,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,calcium,DB01373
,42634,DB00005,10009887,97,127985,35,42384,0.687041137,0.917788149,0.61762762,1.39254034,0.811270273,DB0000510009887_,0.209154021,-0.08578869,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,42635,DB00005,10054236,110,127972,24,42395,0.071342286,1.518339612,0.969400006,2.47053915,0.16359712,DB0000510054236_,1.81034846,0.417617377,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,42638,DB00316,10024774,130,65344,95,36858,0.06043707,0.771892551,0.587718269,1.016838151,0.144202592,DB0031610024774_,1.936536077,-0.258909921,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,42639,DB00451,10024774,88,47183,44,15375,0.025481607,0.651723021,0.448671566,0.958917255,0.074573741,DB0045110024774_,2.595966838,-0.428135622,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,42646,DB01050,10024774,48,18060,16,9355,0.146318087,1.553963432,0.866473687,2.933389507,0.278800402,DB0105010024774_,1.277259159,0.44080872,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,42655,DB00370,10010774,78,4463,63,3600,1,0.998687759,0.705146865,1.419164365,1,DB0037010010774_,0,-0.001313102,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,mirtazapine,DB00370
,42656,DB00715,10010774,79,4764,35,2252,0.839781106,1.066967967,0.705630549,1.642611865,0.917937637,DB0071510010774_,0.085625824,0.06482095,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,paroxetine,DB00715
,42657,DB01156,10010774,198,13424,67,6261,0.023781115,1.378336361,1.038006938,1.849614245,0.070732744,DB0115610010774_,2.648846669,0.320877236,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,42658,DB00715,10016256,330,4513,135,2152,0.150479098,1.165618628,0.944680673,1.444312821,0.284608246,DB0071510016256_,1.256641621,0.153251957,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,42667,DB01104,10029410,61,15402,28,7258,1,1.026646327,0.645623231,1.669839945,1,DB0110410029410_,0,0.026297496,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,sertraline,DB01104
,42668,DB01156,10029410,44,13578,12,6316,0.113572078,1.705561163,0.884727437,3.550125736,0.231485893,DB0115610029410_,1.463236343,0.533894184,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,bupropion,DB01156
,42669,DB00215,10041349,153,10950,106,5170,0.003121043,0.681497827,0.527312492,0.88353167,0.013975683,DB0021510041349_,4.270436418,-0.383462216,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,42670,DB00370,10041349,95,4446,58,3605,0.100523414,1.328055103,0.945068342,1.879968754,0.211626121,DB0037010041349_,1.552934144,0.283715544,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,mirtazapine,DB00370
,42671,DB01104,10041349,189,15274,109,7177,0.091805874,0.814779016,0.639149461,1.042867232,0.198129431,DB0110410041349_,1.618834772,-0.204838349,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,42672,DB01156,10041349,237,13385,83,6245,0.025037335,1.332271117,1.0313681,1.735096288,0.073535544,DB0115610041349_,2.609986393,0.286885093,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,42673,DB00370,10042458,60,4481,36,3627,0.179400645,1.348979127,0.875672315,2.104715925,0.323139514,DB0037010042458_,1.129671116,0.299348104,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,mirtazapine,DB00370
,42674,DB00715,10042458,53,4790,18,2269,0.251277475,1.394730107,0.801701374,2.536283579,0.411221146,DB0071510042458_,0.888624141,0.332700925,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,paroxetine,DB00715
,42675,DB01104,10042458,204,15259,127,7159,0.014858004,0.753603651,0.599795027,0.949842435,0.048937115,DB0110410042458_,3.017219168,-0.282888712,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,42676,DB01156,10042458,248,13374,114,6214,0.954595616,1.010783633,0.804786628,1.275779452,0.992427551,DB0115610042458_,0.007601265,0.010725905,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,42677,DB00186,10042464,71,16830,19,9989,0.001404268,2.217841382,1.320833965,3.900110383,0.007276006,DB0018610042464_,4.923173137,0.796534372,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,42679,DB00715,10042464,22,4821,30,2257,0.000145001,0.343374361,0.188272241,0.61709143,0.001095687,DB0071510042464_,6.816374124,-1.068933997,male,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,paroxetine,DB00715
,42680,DB01104,10042464,110,15353,55,7231,0.737831966,0.941969181,0.674618716,1.328514189,0.848953281,DB0110410042464_,0.163751123,-0.059782721,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,42681,DB00370,10047899,73,4468,54,3609,0.653677455,1.091969428,0.755384501,1.58690105,0.787749099,DB0037010047899_,0.238575642,0.08798288,NA,10047899,Weight increased,10022891,Investigations,Inv,mirtazapine,DB00370
,42682,DB00186,10048010,70,16831,43,9965,0.84589651,0.963794088,0.649495011,1.444913513,0.922531367,DB0018610048010_,0.080633901,-0.036877609,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,42683,DB00215,10048010,51,11052,17,5259,0.2418882,1.4275075,0.80987861,2.639329996,0.400039724,DB0021510048010_,0.916191428,0.355929917,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,42686,DB01104,10048010,75,15388,24,7262,0.105525798,1.474745904,0.919667155,2.444831121,0.219407182,DB0110410048010_,1.516825997,0.388485707,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,42687,DB01156,10048010,70,13552,25,6303,0.271434614,1.302209332,0.813445437,2.148553781,0.434232606,DB0115610048010_,0.834174931,0.264062308,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,42706,DB00215,10074903,109,10994,57,5219,0.559574817,0.907794185,0.651855436,1.275855865,0.712255105,DB0021510074903_,0.339319138,-0.096737594,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,42707,DB00370,10074903,48,4493,14,3649,0.000441317,2.784133312,1.50690724,5.476478964,0.00278278,DB0037010074903_,5.884305004,1.023936626,female,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,mirtazapine,DB00370
,42708,DB01156,10074903,113,13509,52,6276,1,1.009568763,0.719691614,1.43250679,1,DB0115610074903_,0,0.009523272,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,42710,DB00996,10013654,347,38606,355,22070,2.57969475919674e-14,0.558823332,0.480107005,0.650338483,1.43507464011611e-12,DB0099610013654_,27.26980425,-0.581921899,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,42715,DB00043,10025482,229,6184,65,2235,0.09264463,1.273245761,0.958343567,1.711416379,0.199448307,DB0004310025482_,1.612200187,0.241569358,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,42716,DB00555,10012373,52,6995,13,3473,0.024383946,1.985876701,1.064527365,3.981092957,0.07214047,DB0055510012373_,2.629140085,0.68606048,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,42717,DB00656,10012373,37,11976,13,6606,0.183830442,1.569911922,0.814875453,3.221064251,0.328740652,DB0065610012373_,1.112486131,0.451019517,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,42719,DB00734,10033295,59,3991,45,4857,0.022237118,1.595501297,1.061611879,2.412168863,0.067164911,DB0073410033295_,2.700604329,0.46718798,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,42720,DB00734,10070863,226,3824,140,4762,1.23272430356936e-10,2.010124457,1.613583374,2.510855467,3.94907474946018e-09,DB0073410070863_,19.34978453,0.698196639,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,42737,DB00007,10002034,24,1923,90,4362,0.030588034,0.604930923,0.3674652,0.961281107,0.086012996,DB0000710002034_,2.453256882,-0.502641004,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,leuprolide,DB00007
,42738,DB00327,10002034,111,6027,75,4187,0.88063359,1.028166107,0.758059973,1.401043935,0.950087484,DB0032710002034_,0.05120121,0.027776736,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,hydromorphone,DB00327
,42740,DB06643,10002034,166,52255,68,7447,1.52734695552734e-11,0.347907137,0.260569784,0.468924781,5.64645776737499e-10,DB0664310002034_,21.29482253,-1.055819684,male,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,denosumab,DB06643
,42742,DB11089,10002034,293,9882,211,8196,0.123246474,1.15169851,0.95916639,1.384725142,0.246006271,DB1108910002034_,1.402398253,0.141237818,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,docusate,DB11089
,42745,DB00115,10018867,21,18404,43,10429,6.327760658188e-07,0.276758804,0.155924933,0.477006774,9.5452045280041e-06,DB0011510018867_,11.55947167,-1.284608896,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,cyanocobalamin,DB00115
,42747,DB00381,10018867,49,29311,89,22798,1.12610503324352e-06,0.428229476,0.295680263,0.613870035,1.58924406973455e-05,DB0038110018867_,11.04966699,-0.848096068,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,42748,DB00678,10018867,22,15577,44,10680,2.48343782249946e-05,0.342826546,0.195547813,0.58479732,0.00024021,DB0067810018867_,8.333995552,-1.070530656,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,losartan,DB00678
,42753,DB11089,10018867,25,10150,55,8352,2.44400021497234e-05,0.374044187,0.223141753,0.611065169,0.000236915,DB1108910018867_,8.347809363,-0.983381342,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,docusate,DB11089
,42767,DB00115,10021036,45,18380,40,10432,0.041893309,0.638500154,0.407460295,1.003924847,0.1094979,DB0011510021036_,2.211849905,-0.448633362,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,cyanocobalamin,DB00115
,42768,DB00126,10021036,38,10133,17,5928,0.402797721,1.307669065,0.719694664,2.472991824,0.572546945,DB0012610021036_,0.557660547,0.268246213,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,ascorbic acid,DB00126
,42769,DB00678,10021036,51,15548,41,10683,0.458693009,0.854691554,0.55502414,1.323389807,0.626096782,DB0067810021036_,0.468250316,-0.157014631,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,42771,DB01373,10021036,46,22674,13,7368,0.762636888,1.149828945,0.610409846,2.321209714,0.868521505,DB0137310021036_,0.140962932,0.139613188,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,calcium,DB01373
,42797,DB00327,10035528,46,6092,45,4217,0.108413598,0.707639299,0.457919419,1.094109163,0.223642397,DB0032710035528_,1.497706943,-0.34582078,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,hydromorphone,DB00327
,42799,DB00497,10035528,206,19061,171,16204,0.835520275,1.024114675,0.831145143,1.263156837,0.914862473,DB0049710035528_,0.088981527,0.023828508,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,oxycodone,DB00497
,42800,DB00678,10035528,147,15452,96,10628,0.743057271,1.053210132,0.807819004,1.378434502,0.852961276,DB0067810035528_,0.15904113,0.051842768,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,losartan,DB00678
,42801,DB00788,10035528,50,9306,39,5022,0.094480919,0.691850652,0.445398253,1.081721729,0.202476013,DB0078810035528_,1.597133852,-0.368385168,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,naproxen,DB00788
,42802,DB00863,10035528,88,10585,72,5768,0.012485047,0.666005262,0.481390703,0.924062052,0.042492486,DB0086310035528_,3.158428029,-0.406457708,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,ranitidine,DB00863
,42808,DB00169,10056342,72,38619,31,18144,0.751475646,1.09119241,0.706663341,1.721139963,0.859679345,DB0016910056342_,0.151195814,0.087271053,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,42809,DB00186,10056342,42,16859,15,9993,0.099969885,1.659641328,0.901138812,3.223633819,0.210747758,DB0018610056342_,1.557093321,0.506601512,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,42812,DB00381,10056342,44,29316,26,22861,0.279835771,1.319675467,0.794542434,2.233279672,0.443678105,DB0038110056342_,0.812655968,0.277385848,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,42813,DB00497,10056342,39,19228,27,16348,0.459139981,1.228085218,0.732519423,2.087185267,0.626498187,DB0049710056342_,0.467609399,0.205456223,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,42816,DB01373,10056342,51,22669,15,7366,0.88608785,1.104781919,0.611043559,2.116892251,0.95260922,DB0137310056342_,0.048550512,0.099647957,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,42822,DB00335,10046735,75,8391,30,5435,0.026988504,1.619240096,1.045713024,2.565901908,0.077992236,DB0033510046735_,2.551145999,0.481956962,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,atenolol,DB00335
,42823,DB00788,10046735,122,9234,50,5011,0.107756592,1.324092425,0.943496717,1.882476453,0.222712505,DB0078810046735_,1.501873553,0.280727263,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,naproxen,DB00788
,42837,DB00281,10006784,50,11408,13,5658,0.043206673,1.907504433,1.019809506,3.831168425,0.112083633,DB0028110006784_,2.188509964,0.645795808,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,42849,DB10708,10033371,54,966,11,444,0.012943046,2.255302129,1.151842157,4.831575281,0.043725721,DB1070810033371_,3.129818775,0.813283946,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,flax seed,DB10708
,42882,DB00068,10017577,91,2143,33,632,0.326239499,0.813299442,0.534687604,1.26355865,0.494738742,DB0006810017577_,0.703725449,-0.206655919,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,42884,DB00186,10009033,106,16795,54,9954,0.412104015,1.16342664,0.829818194,1.647526678,0.581467284,DB0018610009033_,0.542200571,0.151369651,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,42887,DB00425,10009033,66,12629,48,7436,0.28507277,0.809624266,0.549153442,1.201225717,0.449660211,DB0042510009033_,0.799263067,-0.211185008,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,42892,DB00956,10009033,33,5781,21,3446,0.887953438,0.936721135,0.525095755,1.706568693,0.953581309,DB0095610009033_,0.047530583,-0.065369656,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrocodone,DB00956
,42894,DB01137,10009033,51,7721,34,5559,0.825566844,1.079987441,0.6852258,1.721533479,0.907798883,DB0113710009033_,0.09673242,0.076949412,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,42896,DB08910,10009033,42,16702,66,17422,0.042543157,0.663807155,0.439475315,0.992752223,0.110799791,DB0891010009033_,2.200030389,-0.409763602,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,42899,DB00186,10016288,179,16722,158,9850,0.000273265,0.667371563,0.534968725,0.833138675,0.001869541,DB0018610016288_,6.282062573,-0.404408323,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,lorazepam,DB00186
,42902,DB00341,10016288,35,11370,49,5019,1.71571071725528e-07,0.315328362,0.19806344,0.497281165,2.96012183807385e-06,DB0034110016288_,12.73028013,-1.154140765,male,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,cetirizine,DB00341
,42903,DB00425,10016288,56,12639,55,7429,0.007645769,0.598514218,0.404580558,0.88557166,0.028728329,DB0042510016288_,3.549871559,-0.513304998,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,zolpidem,DB00425
,42904,DB00512,10016288,103,4634,123,4975,0.459015486,0.899037703,0.682947144,1.181472418,0.626390575,DB0051210016288_,0.467781181,-0.106430307,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,vancomycin,DB00512
,42907,DB00916,10016288,33,5290,44,2387,2.93230458908298e-06,0.338474417,0.208213883,0.545379621,3.71269875356677e-05,DB0091610016288_,10.20116643,-1.083306767,male,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,metronidazole,DB00916
,42909,DB01109,10016288,48,4364,49,4221,0.838426428,0.947477586,0.621407378,1.443932416,0.917014548,DB0110910016288_,0.086631942,-0.053951999,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,heparin,DB01109
,42910,DB01413,10016288,66,1154,77,1582,0.385466555,1.174972485,0.825097065,1.669391974,0.555603663,DB0141310016288_,0.587700075,0.161244731,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,cefepime,DB01413
,42911,DB08910,10016288,63,16681,101,17387,0.007633319,0.65017333,0.466576008,0.90007691,0.028691805,DB0891010016288_,3.551143745,-0.430516291,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,pomalidomide,DB08910
,42912,DB09153,10016288,96,7703,120,5579,9.22454009853857e-05,0.579447939,0.437345979,0.765983258,0.000744678,DB0915310016288_,7.202559144,-0.545679458,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,sodium chloride,DB09153
,42915,DB00186,10018884,164,16737,77,9931,0.094400853,1.263777057,0.957102846,1.681065949,0.20235903,DB0018610018884_,1.597711783,0.234104901,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,lorazepam,DB00186
,42916,DB00211,10018884,25,1411,40,1591,0.208795449,0.704811586,0.407574696,1.197482015,0.359869729,DB0021110018884_,1.022013176,-0.349824765,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,midodrine,DB00211
,42918,DB00341,10018884,79,11326,50,5018,0.055108335,0.70003029,0.484289447,1.020199963,0.134539784,DB0034110018884_,2.005895329,-0.356631673,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,cetirizine,DB00341
,42919,DB00425,10018884,108,12587,73,7411,0.395240145,0.871085207,0.640368089,1.190643929,0.564978732,DB0042510018884_,0.570967192,-0.138015481,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,zolpidem,DB00425
,42920,DB00512,10018884,32,4705,30,5068,0.611814228,1.1489447,0.674961074,1.960643089,0.753833824,DB0051210018884_,0.282583327,0.138843869,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,vancomycin,DB00512
,42922,DB00658,10018884,31,1272,50,1346,0.071397748,0.656172909,0.402359609,1.055130728,0.1636886,DB0065810018884_,1.80978944,-0.421330944,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,sevelamer,DB00658
,42923,DB00787,10018884,233,16767,200,17048,0.081810302,1.184516978,0.975138163,1.43983349,0.181399914,DB0078710018884_,1.707051216,0.169335078,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,acyclovir,DB00787
,42925,DB00956,10018884,36,5778,25,3442,0.595960976,0.857839016,0.499913466,1.493602099,0.741456274,DB0095610018884_,0.299139088,-0.153338824,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,hydrocodone,DB00956
,42926,DB01109,10018884,64,4348,80,4190,0.130612617,0.770954855,0.544569324,1.087733259,0.256645932,DB0110910018884_,1.360057842,-0.260125461,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,heparin,DB01109
,42927,DB01137,10018884,55,7717,64,5529,0.008875263,0.615753546,0.420739113,0.898571728,0.032358179,DB0113710018884_,3.430888458,-0.484908483,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,levofloxacin,DB01137
,42929,DB09153,10018884,55,7744,58,5641,0.05551982,0.690788339,0.468059562,1.018392415,0.135203102,DB0915310018884_,2.000977175,-0.369921814,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,sodium chloride,DB09153
,42934,DB00425,10033661,37,12658,53,7431,3.91873992477876e-05,0.409850232,0.261544888,0.636241616,0.000358462,DB0042510033661_,7.933687675,-0.891963474,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,zolpidem,DB00425
,42935,DB00512,10033661,54,4683,62,5036,0.77939913,0.936604153,0.636576414,1.374454871,0.879834487,DB0051210033661_,0.128021472,-0.065494548,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,vancomycin,DB00512
,42941,DB01137,10033661,63,7709,99,5494,7.85367105502539e-07,0.453542337,0.324650318,0.629562606,1.15746422024863e-05,DB0113710033661_,11.36669387,-0.790666657,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,levofloxacin,DB01137
,42942,DB01413,10033661,20,1200,31,1628,0.671021381,0.87533097,0.470360353,1.59420972,0.800371966,DB0141310033661_,0.222678702,-0.133153212,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,cefepime,DB01413
,42943,DB09153,10033661,38,7761,60,5639,0.000187641,0.460190536,0.297714279,0.703498554,0.001366816,DB0915310033661_,6.595271472,-0.776114667,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,sodium chloride,DB09153
,42946,DB00186,10035598,153,16748,101,9907,0.397067624,0.896091262,0.691575552,1.165314884,0.566715853,DB0018610035598_,0.567897243,-0.109713016,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,42949,DB00341,10035598,55,11350,24,5044,1,1.018437517,0.619126339,1.722501066,1,DB0034110035598_,0,0.018269606,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,42950,DB00512,10035598,51,4686,44,5054,0.302820732,1.250084341,0.817059646,1.919477898,0.469180249,DB0051210035598_,0.756768257,0.223211022,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vancomycin,DB00512
,42953,DB00787,10035598,84,16916,112,17136,0.062373733,0.759762389,0.565141626,1.018107605,0.147888649,DB0078710035598_,1.911295657,-0.274749541,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,42956,DB01413,10035598,22,1198,34,1625,0.683674621,0.877750704,0.486335336,1.55385179,0.808795076,DB0141310035598_,0.2122097,-0.130392662,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cefepime,DB01413
,42957,DB08910,10035598,32,16712,29,17459,0.609761412,1.152764809,0.675113914,1.975995153,0.752071471,DB0891010035598_,0.284923919,0.142163239,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,42958,DB09153,10035598,68,7731,52,5647,0.852825173,0.955159438,0.654787756,1.400512965,0.928030734,DB0915310035598_,0.074690428,-0.045877001,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,42961,DB00211,10035664,65,1371,107,1524,0.014798421,0.67535701,0.484074211,0.936326876,0.048798959,DB0021110035664_,3.020046307,-0.392513825,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,midodrine,DB00211
,42962,DB00218,10035664,47,1395,56,894,0.002669632,0.538027667,0.353734259,0.815203528,0.012292419,DB0021810035664_,4.39877258,-0.619845295,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,moxifloxacin,DB00218
,42963,DB00512,10035664,166,4571,189,4909,0.626416824,0.943238995,0.758006938,1.172876314,0.766009128,DB0051210035664_,0.266561193,-0.058435587,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,vancomycin,DB00512
,42964,DB00514,10035664,73,2093,45,1491,0.506511472,1.155559725,0.781251468,1.725421525,0.667292829,DB0051410035664_,0.404526305,0.144584837,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,dextromethorphan,DB00514
,42965,DB00916,10035664,122,5201,88,2343,0.001140523,0.624581183,0.468782215,0.834931061,0.00614128,DB0091610035664_,5.092722159,-0.470673961,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,metronidazole,DB00916
,42966,DB01413,10035664,85,1135,89,1570,0.081616295,1.320945194,0.95971179,1.817186726,0.181060596,DB0141310035664_,1.708923518,0.278347536,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cefepime,DB01413
,42968,DB00572,10011906,209,2693,224,1902,3.64182946334671e-05,0.659051717,0.53814032,0.8068064,0.000336469,DB0057210011906_,7.997003943,-0.416953269,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,atropine,DB00572
,42969,DB00471,10035226,54,14135,46,5419,0.000114616,0.450062013,0.297679054,0.682964647,0.000896498,DB0047110035226_,7.017014858,-0.7983699,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,montelukast,DB00471
,42971,DB00572,10035226,37,2865,25,2101,0.796955043,1.085336213,0.633870225,1.887152421,0.890074285,DB0057210035226_,0.116450354,0.081889813,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,atropine,DB00572
,42972,DB00581,10035226,24,2089,32,2037,0.28239313,0.731388412,0.41067682,1.286346466,0.446451546,DB0058110035226_,0.806424403,-0.312810616,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lactulose,DB00581
,42973,DB00588,10035226,59,16465,54,8414,0.002630934,0.558331692,0.379035552,0.823955089,0.012148283,DB0058810035226_,4.410567448,-0.582802063,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fluticasone propionate,DB00588
,42977,DB00281,10000081,182,11276,71,5600,0.092401756,1.273083386,0.960649432,1.702578118,0.199055866,DB0028110000081_,1.61416976,0.241441821,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,42978,DB00470,10000081,39,880,23,930,0.028361365,1.79143164,1.034047394,3.169527159,0.081074332,DB0047010000081_,2.512388868,0.583015099,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,dronabinol,DB00470
,42980,DB00762,10000081,92,1071,54,1315,2.39320426449375e-05,2.091261469,1.463145734,3.013295734,0.000232631,DB0076210000081_,8.3660565,0.737767457,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,irinotecan,DB00762
,42981,DB11074,10000081,53,1207,37,831,1,0.986209633,0.629553981,1.559085381,1,DB1107410000081_,0,-0.013886337,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,dimethicone,DB11074
,42982,DB00230,10021789,124,19550,56,8595,0.871186147,0.973493062,0.703765731,1.361162111,0.943115942,DB0023010021789_,0.058566054,-0.026864581,NA,10021789,Infection,10021881,Infections and infestations,Infec,pregabalin,DB00230
,42983,DB00281,10021789,122,11336,53,5618,0.467709864,1.140773162,0.818467625,1.608811664,0.634221718,DB0028110021789_,0.455356673,0.131706244,NA,10021789,Infection,10021881,Infections and infestations,Infec,lidocaine,DB00281
,42984,DB00433,10021789,83,7573,65,5955,1,1.004103418,0.715657808,1.413980847,1,DB0043310021789_,0,0.004095022,NA,10021789,Infection,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,42990,DB00722,10021789,206,25197,150,25882,0.001393246,1.41065206,1.136624846,1.754128579,0.007231226,DB0072210021789_,4.929346649,0.344052051,NA,10021789,Infection,10021881,Infections and infestations,Infec,lisinopril,DB00722
,42992,DB00761,10021789,168,15139,91,8534,0.794849789,1.04069533,0.800441776,1.360325971,0.88886159,DB0076110021789_,0.117813747,0.039889076,NA,10021789,Infection,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,42994,DB00836,10021789,61,5474,27,4048,0.029714777,1.670622592,1.043683624,2.739252984,0.084079113,DB0083610021789_,2.475997097,0.513196366,NA,10021789,Infection,10021881,Infections and infestations,Infec,loperamide,DB00836
,42995,DB00904,10021789,214,22855,145,14311,0.478877326,0.924135941,0.744172824,1.150291723,0.644098274,DB0090410021789_,0.439903965,-0.078896096,NA,10021789,Infection,10021881,Infections and infestations,Infec,ondansetron,DB00904
,42998,DB00572,10037660,70,2832,60,2066,0.369795619,0.851137051,0.591287919,1.228379054,0.539419953,DB0057210037660_,0.617260878,-0.161182116,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,atropine,DB00572
,43000,DB11074,10037660,45,1215,53,815,0.008211313,0.569704405,0.370292709,0.873191547,0.030422787,DB1107410037660_,3.492563367,-0.56263764,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,dimethicone,DB11074
,43001,DB00470,10047700,71,848,38,915,0.00072358,2.015285966,1.324437287,3.107749497,0.004208743,DB0047010047700_,5.470591329,0.700761104,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dronabinol,DB00470
,43003,DB11074,10047700,69,1191,34,834,0.1014145,1.420871401,0.919543757,2.232118333,0.212998847,DB1107410047700_,1.546468526,0.351270346,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dimethicone,DB11074
,43022,DB01101,10005191,109,7480,29,3879,0.001060006,1.949055625,1.281397536,3.051584751,0.005784153,DB0110110005191_,5.15263333,0.66734496,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,capecitabine,DB01101
,43023,DB01101,10015150,182,7407,56,3852,0.000518195,1.69008713,1.242881032,2.328997495,0.003179076,DB0110110015150_,5.751164772,0.524780084,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,capecitabine,DB01101
,43027,DB08828,10016256,80,682,114,1028,0.757200739,1.057735329,0.771592823,1.444795172,0.864240275,DB0882810016256_,0.145904453,0.056130141,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,vismodegib,DB08828
,43028,DB08828,10028334,131,631,265,877,0.001521457,0.687196828,0.539691545,0.872206273,0.007782863,DB0882810028334_,4.855831039,-0.375134524,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,vismodegib,DB08828
,43029,DB08828,10028813,77,685,88,1054,0.080560221,1.346109706,0.963131561,1.878404029,0.179329726,DB0882810028813_,1.718529124,0.297218733,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,vismodegib,DB08828
,43048,DB00338,10054236,152,33522,89,22183,0.391419465,1.130198307,0.863855018,1.485993541,0.561325586,DB0033810054236_,0.577454175,0.12239311,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,43049,DB00512,10054236,128,4609,61,5037,5.63205155644534e-08,2.293041847,1.672816527,3.172534805,1.07625209132073e-06,DB0051210054236_,13.74202584,0.829879254,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,vancomycin,DB00512
,43052,DB01190,10054236,64,4870,20,2265,0.126437614,1.488219924,0.886314755,2.603152731,0.25071007,DB0119010054236_,1.383458107,0.397580724,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,clindamycin,DB01190
,43053,DB01307,10012671,64,2460,40,2029,0.195058347,1.319594595,0.871173142,2.02002082,0.343053673,DB0130710012671_,1.069868364,0.277324565,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,insulin detemir,DB01307
,43056,DB00181,10042674,66,9790,23,5848,0.027481967,1.714062641,1.050876499,2.890867359,0.079072136,DB0018110042674_,2.537394734,0.538866366,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,43058,DB00091,10028334,63,5447,23,2647,0.297870516,1.331088476,0.811932821,2.254098652,0.463752088,DB0009110028334_,0.768405162,0.28599701,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclosporine,DB00091
,43059,DB00193,10028334,310,19010,124,8578,0.272500601,1.128080685,0.911593636,1.402986282,0.435487357,DB0019310028334_,0.831289513,0.12051768,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,43060,DB00564,10028334,42,2562,12,1451,0.044522999,1.981942435,1.020356061,4.149341741,0.114625557,DB0056410028334_,2.166084487,0.684077391,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,carbamazepine,DB00564
,43061,DB09153,10028334,54,7745,28,5671,0.146041855,1.412091284,0.877579255,2.318303034,0.278500392,DB0915310028334_,1.278335812,0.345071785,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium chloride,DB09153
,43063,DB00091,10033371,172,5338,36,2634,6.13794061231985e-07,2.357353081,1.632529756,3.488287542,9.28818474351336e-06,DB0009110033371_,11.58676742,0.857539414,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,43064,DB00564,10033371,97,2507,34,1429,0.0159056,1.626006694,1.083321854,2.493158786,0.051608002,DB0056410033371_,2.964078548,0.486127128,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,carbamazepine,DB00564
,43065,DB09153,10033371,206,7593,79,5620,4.0553004940789e-07,1.929922795,1.478409292,2.540109422,6.40778920870838e-06,DB0915310033371_,11.95799624,0.65748,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,43068,DB00181,10048709,45,9811,44,5827,0.020762417,0.607470335,0.391347985,0.943439607,0.063654298,DB0018110048709_,2.754288425,-0.498451937,NA,10048709,Urosepsis,10021881,Infections and infestations,Infec,baclofen,DB00181
,43072,DB00695,10048709,39,28010,21,20507,0.296037019,1.35966303,0.780151213,2.433560589,0.461894035,DB0069510048709_,0.772419776,0.307236897,NA,10048709,Urosepsis,10021881,Infections and infestations,Infec,furosemide,DB00695
,43077,DB00297,10025482,40,1632,10,869,0.034468863,2.129353283,1.040100617,4.799218986,0.094351893,DB0029710025482_,2.360723944,0.755818311,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,bupivacaine,DB00297
,43078,DB00327,10025482,138,6000,73,4189,0.065721484,1.319786816,0.983873692,1.782640023,0.153663868,DB0032710025482_,1.87298774,0.277470221,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,43080,DB00327,10030124,72,6066,38,4224,0.173822287,1.319346591,0.876803329,2.013456407,0.31591487,DB0032710030124_,1.152282501,0.277136607,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,43081,DB00773,10029354,147,2176,210,2617,0.12311383,0.841894339,0.671934367,1.052760863,0.245834847,DB0077310029354_,1.403095321,-0.172100761,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,etoposide,DB00773
,43084,DB09072,10062519,101,6370,37,2498,0.775302227,1.070456876,0.72551616,1.610046457,0.877565198,DB0907210062519_,0.130604026,0.068085545,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,43086,DB00295,10019063,142,14521,79,9523,0.268908553,1.178753009,0.887936041,1.57441195,0.431399269,DB0029510019063_,0.840721241,0.164457108,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,morphine,DB00295
,43091,DB00571,10005750,51,5072,17,2592,0.15587744,1.533044499,0.868671298,2.837540661,0.291971674,DB0057110005750_,1.231098487,0.427255627,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,propranolol,DB00571
,43092,DB00745,10005750,51,2526,24,1059,0.701442428,0.890920532,0.535176739,1.521834736,0.820699037,DB0074510005750_,0.197598818,-0.115500046,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,modafinil,DB00745
,43097,DB00571,10020642,57,5066,23,2586,0.405591561,1.265069003,0.765082802,2.1566467,0.575178812,DB0057110020642_,0.55307431,0.235126668,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,propranolol,DB00571
,43103,DB00182,10016256,290,4904,140,2712,0.213674892,1.145544841,0.927724046,1.419607901,0.365832571,DB0018210016256_,1.005579507,0.135880368,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,43104,DB00422,10016256,241,3194,121,2828,5.21214875459191e-07,1.763343201,1.40293854,2.225579688,8.04227666063311e-06,DB0042210016256_,11.73079835,0.567211553,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,43130,DB00264,10001497,67,29540,79,24813,0.045632881,0.712398568,0.506413421,0.999627402,0.116786942,DB0026410001497_,2.147404017,-0.339117738,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,43131,DB00295,10001497,53,14610,92,9510,6.514560589328e-09,0.375003084,0.261980847,0.532022151,1.52452277505475e-07,DB0029510001497_,15.69641422,-0.980821029,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,morphine,DB00295
,43135,DB00480,10001497,35,67393,52,67610,0.085629118,0.675249502,0.426840133,1.05666399,0.187743368,DB0048010001497_,1.672679311,-0.392673023,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,43136,DB00502,10001497,47,1347,89,1783,0.051719638,0.69909861,0.476654961,1.014209621,0.128274267,DB0050210001497_,2.053584595,-0.357963474,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,haloperidol,DB00502
,43137,DB00682,10001497,32,19427,30,16334,0.702935995,0.896844619,0.527526396,1.52851625,0.821751546,DB0068210001497_,0.196317185,-0.108872654,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,43141,DB11089,10001497,36,10139,39,8368,0.247007329,0.761857484,0.470132741,1.231525665,0.406142103,DB1108910001497_,0.901052174,-0.271995769,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,docusate,DB11089
,43185,DB00178,10002034,32,1405,31,1649,0.523561037,1.21144704,0.711843426,2.064138775,0.681717293,DB0017810002034_,0.383140234,0.191815546,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ramipril,DB00178
,43186,DB00319,10002034,43,1349,49,1804,0.456352169,1.173475223,0.755723153,1.816368543,0.62372757,DB0031910002034_,0.472041592,0.159969623,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,piperacillin,DB00319
,43189,DB01067,10002034,73,4288,92,4731,0.431774042,0.875466775,0.633063171,1.206978893,0.600215812,DB0106710002034_,0.510466001,-0.132998077,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,glipizide,DB01067
,43195,DB00264,10002383,55,29552,60,24832,0.189345843,0.770266215,0.524156139,1.129985013,0.335734715,DB0026410002383_,1.091433968,-0.26101909,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,metoprolol,DB00264
,43200,DB00480,10002383,24,67404,55,67607,0.000638034,0.437653233,0.25906685,0.719112188,0.003793422,DB0048010002383_,5.574486766,-0.826328388,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,43211,DB00188,10002855,53,7833,39,8789,0.046893534,1.524781989,0.988294323,2.37107441,0.119246993,DB0018810002855_,2.12655837,0.421851442,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,bortezomib,DB00188
,43213,DB00399,10002855,91,6901,32,4966,0.000315869,2.046252415,1.351713819,3.169960253,0.002105124,DB0039910002855_,6.163380751,0.71601003,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,zoledronic acid,DB00399
,43214,DB00480,10002855,371,67057,287,67375,0.000887215,1.298806832,1.109940432,1.521096473,0.004994209,DB0048010002855_,5.299476274,0.261446021,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,43215,DB00502,10002855,23,1371,30,1842,1,1.03005487,0.5686699,1.843143918,1,DB0050210002855_,0,0.029612073,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,haloperidol,DB00502
,43218,DB01067,10002855,49,4312,23,4800,0.000514169,2.371336094,1.414696944,4.085416651,0.0031588,DB0106710002855_,5.757563141,0.863453549,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,glipizide,DB01067
,43219,DB01137,10002855,156,7616,60,5533,1.97258609273191e-05,1.888796682,1.390852735,2.593574882,0.000197446,DB0113710002855_,8.530043387,0.63593995,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,levofloxacin,DB01137
,43220,DB01234,10002855,315,31310,205,32683,1.14200078011643e-07,1.603944053,1.339999603,1.923207856,2.04757779709143e-06,DB0123410002855_,13.09885303,0.472465629,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,43221,DB11089,10002855,181,9994,86,8321,1.34981857407039e-05,1.752276103,1.345869645,2.296247195,0.000141326,DB1108910002855_,8.864438773,0.560915573,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,docusate,DB11089
,43284,DB00178,10003239,34,1403,28,1652,0.197860842,1.429615142,0.836764488,2.460743369,0.346406382,DB0017810003239_,1.060142678,0.357405276,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ramipril,DB00178
,43285,DB00254,10003239,113,5822,36,3352,0.001891879,1.807100474,1.228688894,2.714945764,0.009293223,DB0025410003239_,4.678469874,0.591723613,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,doxycycline,DB00254
,43287,DB00332,10003239,70,2614,28,1628,0.057782269,1.556850228,0.986375052,2.518393948,0.139314525,DB0033210003239_,1.971021134,0.442664695,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ipratropium,DB00332
,43289,DB00537,10003239,178,7379,75,4223,0.028999097,1.358224444,1.028462515,1.80843586,0.08247579,DB0053710003239_,2.495250477,0.306178291,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ciprofloxacin,DB00537
,43291,DB00999,10003239,663,20767,214,12025,1.97061085006559e-14,1.793922412,1.532819306,2.106202366,1.11153446768185e-12,DB0099910003239_,27.52527965,0.584404514,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,43293,DB01067,10003239,99,4262,71,4752,0.005153598,1.554586593,1.13122284,2.145662922,0.020953181,DB0106710003239_,3.865464822,0.441209654,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,glipizide,DB01067
,43294,DB01137,10003239,219,7553,77,5516,1.16404442227638e-08,2.076979642,1.591028812,2.73572692,2.579840441782e-07,DB0113710003239_,15.1703681,0.730914743,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,43295,DB11089,10003239,196,9979,103,8304,0.000168661,1.583461852,1.23879343,2.03378461,0.001248279,DB1108910003239_,6.685989256,0.459613496,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,43298,DB00188,10003285,36,7850,23,8805,0.03650618,1.755559087,1.011266231,3.106173879,0.098598945,DB0018810003285_,2.31669472,0.562787374,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,bortezomib,DB00188
,43300,DB00264,10003285,93,29514,62,24830,0.169950177,1.261936821,0.904946858,1.770318542,0.310846521,DB0026410003285_,1.16845599,0.232647701,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,43301,DB00295,10003285,32,14631,33,9569,0.074989569,0.63423501,0.37727378,1.064875471,0.169806853,DB0029510003285_,1.773093647,-0.455335715,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,43304,DB00399,10003285,37,6955,35,4963,0.233272229,0.754391013,0.461493907,1.23536592,0.389862377,DB0039910003285_,0.941961482,-0.281844461,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,43307,DB00682,10003285,61,19398,47,16317,0.699219327,1.091760864,0.733632547,1.633637192,0.819155395,DB0068210003285_,0.199481476,0.087791865,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,43312,DB01234,10003285,124,31501,106,32782,0.146133968,1.217376086,0.931288973,1.593759275,0.278606063,DB0123410003285_,1.277956457,0.196697793,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,43313,DB11089,10003285,35,10140,22,8385,0.352014858,1.315538636,0.749738019,2.356057121,0.521756877,DB1108910003285_,0.650553553,0.274246191,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,43336,DB00178,10003549,56,1381,52,1628,0.238991664,1.269433051,0.848442787,1.90219257,0.396747143,DB0017810003549_,0.92445612,0.238570384,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ramipril,DB00178
,43337,DB00319,10003549,43,1349,24,1829,0.00043374,2.428522532,1.433011435,4.205278016,0.002742236,DB0031910003549_,5.898981615,0.887283061,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,piperacillin,DB00319
,43338,DB00332,10003549,74,2610,46,1610,1,0.992337619,0.673836249,1.474698577,1,DB0033210003549_,0,-0.007691888,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ipratropium,DB00332
,43339,DB00399,10003549,300,6692,205,4793,0.644771455,1.04814234,0.87114145,1.262986745,0.780709787,DB0039910003549_,0.24755179,0.047019397,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,43341,DB00537,10003549,191,7366,129,4169,0.125850655,0.838020801,0.664517241,1.059576998,0.249838335,DB0053710003549_,1.386941231,-0.176712356,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,43343,DB11089,10003549,416,9759,321,8086,0.364831115,1.073803175,0.923201237,1.249788513,0.534401384,DB1108910003549_,0.626608066,0.071206715,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,43347,DB00264,10003598,32,29575,33,24859,0.455361626,0.815076018,0.485099184,1.36792457,0.622843333,DB0026410003598_,0.473460264,-0.204473896,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,43361,DB01234,10003598,28,31597,32,32856,0.796448455,0.909882202,0.527707639,1.56034657,0.889807667,DB0123410003598_,0.116749944,-0.094440136,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,43363,DB00178,10003658,20,1417,30,1650,0.395463359,0.776351246,0.415900404,1.420127791,0.56511658,DB0017810003658_,0.570723232,-0.253150224,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ramipril,DB00178
,43364,DB00186,10003658,140,16761,117,9891,0.006374927,0.706158697,0.547707851,0.911721946,0.02485205,DB0018610003658_,3.694815025,-0.347915284,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,lorazepam,DB00186
,43365,DB00254,10003658,38,5897,47,3341,0.000391792,0.458102972,0.290032136,0.719456243,0.002520067,DB0025410003658_,5.983469796,-0.780661291,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,doxycycline,DB00254
,43366,DB00295,10003658,60,14603,87,9515,1.66690191858972e-06,0.449374803,0.31756553,0.63228889,2.2613944222003e-05,DB0029510003658_,10.69694384,-0.799897989,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,morphine,DB00295
,43368,DB00332,10003658,51,2633,29,1627,0.816469449,1.086690384,0.672684342,1.785943357,0.901737409,DB0033210003658_,0.103431923,0.083136733,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ipratropium,DB00332
,43369,DB00399,10003658,56,6936,88,4910,3.3558090885061e-06,0.450508495,0.315688647,0.638320842,4.17179593685778e-05,DB0039910003658_,10.08457884,-0.797378345,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,zoledronic acid,DB00399
,43371,DB00537,10003658,33,7524,55,4243,5.8108951359106e-07,0.338389582,0.212499546,0.531355318,8.85189096768531e-06,DB0053710003658_,11.63487945,-1.083557438,male,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ciprofloxacin,DB00537
,43373,DB01041,10003658,21,3024,40,3078,0.020329442,0.534430668,0.298628394,0.930740847,0.062603889,DB0104110003658_,2.770927879,-0.62655327,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,thalidomide,DB01041
,43374,DB01067,10003658,38,4323,63,4760,0.056455024,0.664179183,0.431010935,1.011362896,0.136892123,DB0106710003658_,1.988562088,-0.409203311,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,glipizide,DB01067
,43377,DB00188,10003988,174,7712,138,8690,0.002374851,1.420726286,1.127241972,1.793541375,0.011192929,DB0018810003988_,4.492473012,0.35116821,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bortezomib,DB00188
,43378,DB00254,10003988,84,5851,64,3324,0.084887547,0.745686877,0.53067178,1.052048575,0.186592171,DB0025410003988_,1.678829949,-0.293449503,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,doxycycline,DB00254
,43379,DB00295,10003988,260,14403,175,9427,0.804665878,0.972411064,0.798295963,1.186867639,0.894419007,DB0029510003988_,0.111580926,-0.027976659,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,43381,DB00332,10003988,55,2629,34,1622,1,0.998031378,0.636084628,1.586102721,1,DB0033210003988_,0,-0.001970563,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ipratropium,DB00332
,43382,DB00399,10003988,250,6742,143,4855,0.032842996,1.258913888,1.017437162,1.562508061,0.090950546,DB0039910003988_,2.397439366,0.230249356,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,43384,DB00537,10003988,127,7430,55,4243,0.102446597,1.318607364,0.951400947,1.84817186,0.214660513,DB0053710003988_,1.538697509,0.276576152,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ciprofloxacin,DB00537
,43387,DB01137,10003988,142,7630,79,5514,0.073606296,1.298957322,0.977410976,1.736592709,0.167524399,DB0113710003988_,1.786626272,0.261561883,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,43390,DB00188,10004146,12,7874,38,8790,0.000954995,0.352565646,0.167593988,0.689745997,0.005303621,DB0018810004146_,5.239365437,-1.042518445,male,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,bortezomib,DB00188
,43399,DB00999,10004146,31,21399,29,12210,0.060002421,0.609978059,0.355425784,1.049500392,0.143469811,DB0099910004146_,1.941630645,-0.494332292,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,hydrochlorothiazide,DB00999
,43427,DB00186,10005425,35,16866,16,9992,0.468959368,1.295938324,0.698202447,2.508824426,0.635342473,DB0018610005425_,0.453591098,0.259235007,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,lorazepam,DB00186
,43434,DB00480,10005425,73,67355,61,67601,0.300701756,1.201088766,0.843039816,1.71645247,0.466984471,DB0048010005425_,0.761459274,0.183228451,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,lenalidomide,DB00480
,43439,DB00999,10005425,76,21354,31,12208,0.130739222,1.401564169,0.911197788,2.203879139,0.256798719,DB0099910005425_,1.359462694,0.337588876,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,43443,DB01234,10005425,56,31569,37,32851,0.037376932,1.574954691,1.021195954,2.454892114,0.100332174,DB0123410005425_,2.299268855,0.454226504,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,dexamethasone,DB01234
,43449,DB00295,10006093,49,14614,65,9537,0.000230204,0.49196142,0.332115535,0.724626077,0.001620778,DB0029510006093_,6.424849256,-0.709354981,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,morphine,DB00295
,43453,DB00480,10006093,46,67382,55,67607,0.426056922,0.839158526,0.55455471,1.264613486,0.594773566,DB0048010006093_,0.519574506,-0.175355644,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,43458,DB01234,10006093,47,31578,91,32797,0.000442259,0.536429012,0.368809858,0.771266372,0.002788052,DB0123410006093_,5.882412034,-0.622821043,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,43461,DB00188,10006451,60,7826,52,8776,0.184325425,1.293886013,0.876423337,1.915682693,0.329336882,DB0018810006451_,1.110674093,0.257650103,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,bortezomib,DB00188
,43462,DB00295,10006451,75,14588,29,9573,0.015581729,1.697094489,1.091112188,2.705051907,0.050792552,DB0029510006451_,2.98000555,0.528917665,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,morphine,DB00295
,43464,DB00332,10006451,68,2616,20,1636,0.00257344,2.125964197,1.26985782,3.710737834,0.011935222,DB0033210006451_,4.428261387,0.754225439,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,ipratropium,DB00332
,43466,DB00537,10006451,60,7497,20,4278,0.035894581,1.71181264,1.015562016,3.002806104,0.09732193,DB0053710006451_,2.329730929,0.537552832,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,43469,DB01137,10006451,147,7625,62,5531,0.000295992,1.719773313,1.26700279,2.358159263,0.001995425,DB0113710006451_,6.216898145,0.542192487,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,levofloxacin,DB01137
,43470,DB11089,10006451,105,10070,47,8360,0.000399786,1.854595381,1.301142545,2.678335676,0.002561147,DB1108910006451_,5.967299958,0.617666549,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,docusate,DB11089
,43502,DB00480,10006811,32,67396,27,67635,0.518176839,1.189385089,0.690243192,2.063812883,0.677510079,DB0048010006811_,0.389330849,0.173436441,NA,10006811,Bursitis,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,43535,DB00254,10007559,40,5895,30,3358,0.263219223,0.759555647,0.460404177,1.265369557,0.425008741,DB0025410007559_,0.855645544,-0.275021691,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,doxycycline,DB00254
,43541,DB11089,10007559,111,10064,119,8288,0.053020722,0.768182045,0.586710828,1.005128868,0.130668948,DB1108910007559_,2.035088265,-0.263728536,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,docusate,DB11089
,43544,DB00254,10010305,38,5897,34,3354,0.064439341,0.635678999,0.388794903,1.043180368,0.151433892,DB0025410010305_,1.887606106,-0.453061561,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,doxycycline,DB00254
,43545,DB00332,10010305,33,2651,24,1632,0.583592137,0.846511831,0.483414203,1.502604071,0.731560165,DB0033210010305_,0.312575813,-0.166631101,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ipratropium,DB00332
,43546,DB00399,10010305,53,6939,47,4951,0.30860735,0.804609713,0.532000977,1.220186427,0.475957531,DB0039910010305_,0.74242665,-0.217397948,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,zoledronic acid,DB00399
,43547,DB00537,10010305,70,7487,51,4247,0.183763779,0.778611572,0.533912812,1.142157477,0.328665391,DB0053710010305_,1.112715094,-0.250242981,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ciprofloxacin,DB00537
,43560,DB00480,10010741,41,67387,19,67643,0.004371432,2.16606974,1.228896051,3.951857783,0.018348442,DB0048010010741_,3.998210594,0.772914346,NA,10010741,Conjunctivitis,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,43572,DB00178,10010774,27,1410,40,1640,0.386272222,0.785167618,0.460823981,1.319069119,0.556444543,DB0017810010774_,0.586187767,-0.241858058,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ramipril,DB00178
,43573,DB00254,10010774,73,5862,37,3351,0.618375745,1.127850826,0.747541756,1.727510806,0.759266913,DB0025410010774_,0.275401899,0.120313898,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,doxycycline,DB00254
,43575,DB00332,10010774,63,2621,26,1630,0.097596071,1.506776247,0.935867236,2.49020911,0.207289622,DB0033210010774_,1.573638324,0.409972433,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ipratropium,DB00332
,43576,DB00399,10010774,211,6781,162,4836,0.488470496,0.928887044,0.750706704,1.151054399,0.652029911,DB0039910010774_,0.427664842,-0.073768136,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,43577,DB00480,10010774,1467,65961,1396,66266,0.156535406,1.055740447,0.979650273,1.137718157,0.292776401,DB0048010010774_,1.228346099,0.054242366,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,43579,DB00537,10010774,131,7426,60,4238,0.172265693,1.246033159,0.908907943,1.724980585,0.313834471,DB0053710010774_,1.158889596,0.219965033,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ciprofloxacin,DB00537
,43581,DB00999,10010774,447,20983,197,12042,0.002184501,1.30217404,1.097051491,1.550052555,0.0104599,DB0099910010774_,4.560206403,0.264035206,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,43582,DB01041,10010774,83,2962,71,3047,0.288714093,1.202523079,0.861658303,1.681926463,0.453770028,DB0104110010774_,0.790164756,0.184421915,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,thalidomide,DB01041
,43583,DB01067,10010774,84,4277,83,4740,0.48211024,1.121591045,0.815726858,1.542438582,0.646560763,DB0106710010774_,0.436088098,0.114748253,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,glipizide,DB01067
,43589,DB00480,10011078,36,67392,94,67568,3.70615309828733e-07,0.383959764,0.253889901,0.56951482,5.90222564001711e-06,DB0048010011078_,12.04018105,-0.957217512,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,43594,DB01234,10011078,16,31609,43,32845,0.000953963,0.386618151,0.203253161,0.700722711,0.00530013,DB0123410011078_,5.240023956,-0.950317763,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,43597,DB00178,10011224,39,1398,35,1645,0.28822913,1.311036185,0.804327953,2.144239012,0.453238172,DB0017810011224_,0.791337525,0.270817806,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ramipril,DB00178
,43598,DB00188,10011224,92,7794,84,8744,0.196819023,1.228716393,0.902589405,1.67456835,0.345168669,DB0018810011224_,1.063722085,0.205970041,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bortezomib,DB00188
,43599,DB00254,10011224,120,5815,78,3310,0.370854061,0.875736294,0.650848892,1.183970873,0.540528945,DB0025410011224_,0.615207092,-0.132690268,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxycycline,DB00254
,43600,DB00264,10011224,562,29045,383,24509,0.001388126,1.238196696,1.084213934,1.415221592,0.00721156,DB0026410011224_,4.932070003,0.213656044,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,43601,DB00319,10011224,31,1361,23,1830,0.036848862,1.811911593,1.017634389,3.270175715,0.099269481,DB0031910011224_,2.309917094,0.594382417,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,piperacillin,DB00319
,43604,DB01067,10011224,101,4260,68,4755,0.001384938,1.65777334,1.203434774,2.295525666,0.007199689,DB0106710011224_,4.933717512,0.505475341,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glipizide,DB01067
,43606,DB00178,10011906,49,1388,81,1599,0.05875605,0.696980528,0.474925008,1.013893961,0.141170272,DB0017810011906_,1.957788511,-0.360997805,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ramipril,DB00178
,43607,DB00254,10011906,103,5832,140,3248,1.07053602083323e-11,0.409778356,0.313411617,0.534347997,4.07221987085405e-10,DB0025410011906_,21.62166266,-0.89213886,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,43608,DB00319,10011906,29,1363,36,1817,0.800973779,1.073852942,0.631696864,1.811274043,0.892358774,DB0031910011906_,0.113887015,0.071253061,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,piperacillin,DB00319
,43609,DB00332,10011906,125,2559,137,1519,2.001039214379e-06,0.541661722,0.418007894,0.701399715,2.64840461983645e-05,DB0033210011906_,10.53896804,-0.613113602,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ipratropium,DB00332
,43612,DB00178,10012174,25,1412,35,1645,0.515535054,0.832202225,0.474951267,1.438546035,0.675313411,DB0017810012174_,0.392578384,-0.183679809,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ramipril,DB00178
,43613,DB00254,10012174,50,5885,31,3357,0.728621739,0.920063375,0.575057638,1.493174154,0.841801345,DB0025410012174_,0.172211224,-0.083312726,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,doxycycline,DB00254
,43614,DB00295,10012174,177,14486,133,9469,0.242391206,0.869924109,0.689692504,1.099376463,0.400606945,DB0029510012174_,0.91477452,-0.139349302,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,morphine,DB00295
,43618,DB00537,10012174,108,7449,64,4234,0.810771108,0.959196756,0.695934473,1.331158942,0.89822005,DB0053710012174_,0.107340197,-0.041659057,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ciprofloxacin,DB00537
,43620,DB01041,10012174,15,3030,37,3081,0.003167567,0.412259264,0.209752284,0.771463167,0.01414294,DB0104110012174_,4.258539714,-0.886102845,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,thalidomide,DB01041
,43621,DB01067,10012174,63,4298,71,4752,0.930769164,0.981052353,0.68569153,1.400832119,0.971923863,DB0106710012174_,0.028477808,-0.019129454,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,glipizide,DB01067
,43622,DB01137,10012174,105,7667,81,5512,0.653749456,0.931945516,0.689276569,1.263873839,0.787753851,DB0113710012174_,0.23856961,-0.070480925,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,levofloxacin,DB01137
,43623,DB11089,10012174,213,9962,151,8256,0.151222457,1.169020108,0.942532476,1.452831196,0.285557506,DB1108910012174_,1.253311848,0.156165883,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,43625,DB00178,10012735,79,1358,94,1586,0.937540241,0.981531841,0.71184491,1.350583211,0.977492476,DB0017810012735_,0.022764685,-0.018640825,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ramipril,DB00178
,43626,DB00332,10012735,118,2566,67,1589,0.642691692,1.0906166,0.795754084,1.504884753,0.779114545,DB0033210012735_,0.249597203,0.086743224,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ipratropium,DB00332
,43628,DB00537,10012735,430,7127,208,4090,0.051434346,1.186315462,0.99837487,1.413174842,0.127723361,DB0053710012735_,2.057888593,0.170852253,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ciprofloxacin,DB00537
,43630,DB01041,10012735,51,2994,56,3062,0.770071808,0.931379393,0.622410472,1.391081179,0.874040593,DB0104110012735_,0.134628459,-0.071088574,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,thalidomide,DB01041
,43633,DB00186,10013950,129,16772,79,9929,0.82910639,0.966657222,0.724163845,1.297275778,0.910222971,DB0018610013950_,0.094065686,-0.033911323,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,43635,DB00254,10013950,39,5896,33,3355,0.109261329,0.672548352,0.411275286,1.105726696,0.224924343,DB0025410013950_,1.491991188,-0.396681271,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,doxycycline,DB00254
,43636,DB00295,10013950,63,14600,57,9545,0.076173031,0.722609708,0.496447446,1.053764809,0.171752788,DB0029510013950_,1.761699113,-0.324886025,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,43639,DB00399,10013950,49,6943,23,4975,0.094849649,1.52650785,0.911072062,2.628951894,0.203006516,DB0039910013950_,1.594517202,0.422982676,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,43640,DB00480,10013950,165,67263,135,67527,0.082869529,1.227015259,0.971186688,1.552440897,0.183182707,DB0048010013950_,1.697271223,0.204584602,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,43641,DB00502,10013950,13,1381,42,1830,0.003699507,0.410264836,0.201240623,0.782807898,0.016020803,DB0050210013950_,4.13386723,-0.890952386,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,haloperidol,DB00502
,43642,DB00537,10013950,48,7509,28,4270,0.905268605,0.974816531,0.598319313,1.616227226,0.957775933,DB0053710013950_,0.043141419,-0.025505999,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,ciprofloxacin,DB00537
,43643,DB00682,10013950,97,19362,64,16300,0.132755072,1.275926699,0.920410981,1.779273804,0.259652386,DB0068210013950_,1.34841152,0.243672738,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,43645,DB00999,10013950,133,21297,59,12180,0.114044151,1.289228068,0.941116627,1.784278782,0.232240985,DB0099910013950_,1.459979716,0.254043642,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,43648,DB01137,10013950,48,7724,40,5553,0.516254551,0.862725861,0.554373796,1.348999658,0.675921593,DB0113710013950_,0.391678196,-0.147658296,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,43649,DB01234,10013950,150,31475,121,32767,0.038425925,1.290546665,1.008378888,1.654493003,0.102499029,DB0123410013950_,2.277901952,0.2550659,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,43650,DB11089,10013950,88,10087,69,8338,0.809226706,1.05423473,0.759428862,1.468492631,0.897167018,DB1108910013950_,0.108513238,0.052815129,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,43653,DB00188,10015150,40,7846,27,8801,0.049073945,1.661737662,0.993787694,2.818634315,0.123235754,DB0018810015150_,2.093656063,0.507863839,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,bortezomib,DB00188
,43654,DB00254,10015150,64,5871,30,3358,0.390724211,1.220209597,0.7773419,1.954810082,0.560614966,DB0025410015150_,0.578720943,0.199022645,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,doxycycline,DB00254
,43655,DB00264,10015150,198,29409,126,24766,0.013864817,1.323327696,1.052414875,1.669065418,0.04619848,DB0026410015150_,3.074808379,0.280149546,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,43656,DB00295,10015150,73,14590,38,9564,0.284671919,1.259259422,0.838847388,1.917745999,0.4492193,DB0029510015150_,0.800244092,0.230523788,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,morphine,DB00295
,43659,DB00399,10015150,85,6907,34,4964,0.003628095,1.79663826,1.19171503,2.763681466,0.015773152,DB0039910015150_,4.149446031,0.585917285,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,zoledronic acid,DB00399
,43660,DB00480,10015150,231,67197,166,67496,0.001062977,1.397748727,1.139709296,1.717183635,0.005792546,DB0048010015150_,5.1511833,0.33486289,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,43662,DB00537,10015150,57,7500,32,4266,1,1.013174155,0.644868152,1.617340839,1,DB0053710015150_,0,0.01308813,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,ciprofloxacin,DB00537
,43663,DB00682,10015150,213,19246,87,16277,3.141623059196e-09,2.070506193,1.604703718,2.691026173,7.90260354492587e-08,DB0068210015150_,16.35348848,0.727793115,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,43667,DB11089,10015150,58,10117,43,8364,0.617328108,1.115085557,0.737897129,1.696695073,0.758370262,DB1108910015150_,0.27658354,0.108931134,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,docusate,DB11089
,43673,DB00264,10015958,63,29544,28,24864,0.004316848,1.893534543,1.19488672,3.071194455,0.01817238,DB0026410015958_,4.007852431,0.638445211,NA,10015958,Eye pain,10015919,Eye disorders,Eye,metoprolol,DB00264
,43678,DB00480,10015958,81,67347,35,67627,1.58846429313545e-05,2.324026404,1.544947932,3.561048557,0.000162747,DB0048010015958_,8.723312726,0.8433012,NA,10015958,Eye pain,10015919,Eye disorders,Eye,lenalidomide,DB00480
,43683,DB00999,10015958,57,21373,18,12221,0.029876136,1.810657444,1.049630984,3.270748413,0.084449322,DB0099910015958_,2.471603666,0.593690008,NA,10015958,Eye pain,10015919,Eye disorders,Eye,hydrochlorothiazide,DB00999
,43687,DB01234,10015958,69,31556,33,32855,0.000210455,2.176943254,1.417580882,3.404302616,0.001503619,DB0123410015958_,6.499880716,0.777921716,NA,10015958,Eye pain,10015919,Eye disorders,Eye,dexamethasone,DB01234
,43697,DB00480,10016165,47,67381,42,67620,0.597704452,1.123015372,0.724723355,1.745297635,0.742836704,DB0048010016165_,0.297279038,0.116017364,NA,10016165,Failure to thrive,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,43706,DB01234,10016165,44,31581,40,32848,0.585582641,1.144127659,0.728308444,1.802106438,0.733042313,DB0123410016165_,0.310551854,0.134642477,NA,10016165,Failure to thrive,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,43707,DB11089,10016165,29,10146,36,8371,0.105675569,0.664649561,0.39273288,1.115869365,0.21965777,DB1108910016165_,1.515684534,-0.408495354,NA,10016165,Failure to thrive,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,43709,DB00178,10016173,49,1388,39,1641,0.082125563,1.485218836,0.949116025,2.337965189,0.181874666,DB0017810016173_,1.704437475,0.395562126,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ramipril,DB00178
,43710,DB00188,10016173,155,7731,158,8670,0.423762324,1.100158718,0.873832159,1.384927462,0.592543889,DB0018810016173_,0.523330335,0.095454458,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,bortezomib,DB00188
,43711,DB00254,10016173,109,5826,53,3335,0.365051119,1.177283224,0.837818399,1.67181298,0.534665181,DB0025410016173_,0.626114559,0.163209431,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,doxycycline,DB00254
,43713,DB00332,10016173,82,2602,45,1611,0.578309239,1.128205002,0.770474373,1.670243676,0.72707028,DB0033210016173_,0.318732135,0.120627876,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ipratropium,DB00332
,43714,DB00399,10016173,227,6765,125,4873,0.018220169,1.308080968,1.043534386,1.645784895,0.057389711,DB0039910016173_,2.857890236,0.268561153,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,zoledronic acid,DB00399
,43715,DB00502,10016173,37,1357,40,1832,0.352312644,1.248689425,0.771988101,2.015161159,0.522058678,DB0050210016173_,0.649975288,0.222094541,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,haloperidol,DB00502
,43716,DB00537,10016173,166,7391,71,4227,0.047543205,1.337114355,1.003982708,1.796178039,0.120473648,DB0053710016173_,2.116324242,0.290513825,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ciprofloxacin,DB00537
,43718,DB00999,10016173,613,20817,268,11971,0.00019127,1.315329417,1.135532473,1.526811941,0.001387673,DB0099910016173_,6.580126951,0.274087142,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,43719,DB01041,10016173,84,2961,61,3057,0.043390696,1.421606624,1.006021604,2.018814678,0.112433404,DB0104110016173_,2.185394201,0.351787657,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,thalidomide,DB01041
,43721,DB00188,10016256,580,7306,604,8224,0.204689686,1.08090718,0.958628688,1.218714937,0.35468736,DB0018810016256_,1.036518554,0.07780067,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,43722,DB00319,10016256,47,1345,30,1823,0.001504851,2.122969789,1.307035894,3.496811286,0.007712784,DB0031910016256_,4.864876056,0.752815952,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,piperacillin,DB00319
,43723,DB00332,10016256,168,2516,96,1560,0.556804863,1.085050632,0.83238311,1.42076104,0.710100421,DB0033210016256_,0.342348881,0.081626652,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ipratropium,DB00332
,43725,DB01041,10016256,147,2898,125,2993,0.121293031,1.214509956,0.944879572,1.563004422,0.243286581,DB0104110016256_,1.413515184,0.194340667,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,thalidomide,DB01041
,43726,DB01137,10016256,455,7317,285,5308,0.06032312,1.158119997,0.992239048,1.353529703,0.144047521,DB0113710016256_,1.937612025,0.146797998,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,43729,DB00188,10017577,51,7835,48,8780,0.419729165,1.190636074,0.785900297,1.806359851,0.588667275,DB0018810017577_,0.529894153,0.17448768,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,43730,DB00254,10017577,67,5868,17,3371,0.001915375,2.263918978,1.311636311,4.120410615,0.009395473,DB0025410017577_,4.667527329,0.817097373,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,43733,DB00399,10017577,104,6888,51,4947,0.026754962,1.464529667,1.03559233,2.094036879,0.077455165,DB0039910017577_,2.558056029,0.381534145,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,43734,DB00480,10017577,312,67116,293,67369,0.415475769,1.068891715,0.90802546,1.258438601,0.584686829,DB0048010017577_,0.53667891,0.066622331,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,43738,DB01067,10017577,60,4301,36,4787,0.003806434,1.854853516,1.204403654,2.893183698,0.016387209,DB0106710017577_,4.111254184,0.617805726,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,43744,DB00264,10018092,31,29576,21,24871,0.487957194,1.241349603,0.690651154,2.273534445,0.65159291,DB0026410018092_,0.428335283,0.216199177,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,43749,DB00480,10018092,28,67400,36,67626,0.381665509,0.780389152,0.458639672,1.315319788,0.551789115,DB0048010018092_,0.594589343,-0.24796257,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,43805,DB00264,10019022,42,29565,24,24868,0.138940426,1.471963468,0.870760974,2.542071568,0.268345574,DB0026410019022_,1.315479672,0.386597202,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,43812,DB00682,10019022,37,19422,43,16321,0.177226374,0.723092092,0.452796692,1.149678062,0.320324499,DB0068210019022_,1.138420737,-0.324218691,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,43814,DB00999,10019022,53,21377,26,12213,0.560139107,1.164626002,0.715003629,1.941209079,0.712766268,DB0099910019022_,0.338601727,0.152400007,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,43818,DB01234,10019022,37,31588,23,32865,0.053113908,1.673704621,0.968306305,2.951145662,0.130849531,DB0123410019022_,2.033707233,0.515039506,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,43821,DB00186,10020635,41,16860,59,9949,1.03033281971299e-05,0.410077344,0.268193551,0.621797669,0.000111427,DB0018610020635_,9.102142152,-0.891409493,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,lorazepam,DB00186
,43824,DB00295,10020635,21,14642,34,9568,0.001263972,0.403622455,0.222469012,0.716254308,0.006668039,DB0029510020635_,5.010429488,-0.907275356,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,morphine,DB00295
,43830,DB00682,10020635,22,19437,43,16321,0.001067806,0.429615099,0.244634841,0.734584392,0.005813746,DB0068210020635_,5.14753019,-0.844865589,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,43833,DB01067,10020635,26,4335,33,4790,0.695167223,0.870587754,0.499133851,1.503597781,0.816560818,DB0106710020635_,0.202653883,-0.138586716,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,glipizide,DB01067
,43834,DB01137,10020635,19,7753,32,5561,0.003976644,0.425904032,0.227839539,0.775523082,0.017000259,DB0113710020635_,4.074526682,-0.853541236,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,levofloxacin,DB01137
,43835,DB11089,10020635,33,10142,45,8362,0.030103791,0.604652346,0.37341825,0.969835756,0.08492387,DB1108910020635_,2.466000076,-0.503101621,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,43858,DB00178,10020772,25,1412,30,1650,1,0.973800844,0.546363515,1.721830466,1,DB0017810020772_,0,-0.026548468,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ramipril,DB00178
,43859,DB00186,10020772,233,16668,116,9892,0.132314959,1.192095227,0.948614498,1.50472562,0.259071004,DB0018610020772_,1.350653108,0.175712454,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,lorazepam,DB00186
,43860,DB00254,10020772,41,5894,36,3352,0.073526822,0.647763691,0.402922796,1.045326366,0.16739444,DB0025410020772_,1.787402336,-0.434229323,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,doxycycline,DB00254
,43861,DB00295,10020772,121,14542,86,9516,0.568492052,0.920702048,0.691679819,1.229982099,0.719528763,DB0029510020772_,0.329158777,-0.082618804,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,morphine,DB00295
,43863,DB00332,10020772,45,2639,31,1625,0.635416568,0.893875978,0.550779355,1.467643874,0.773416276,DB0033210020772_,0.256937855,-0.11218824,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ipratropium,DB00332
,43864,DB00399,10020772,82,6910,43,4955,0.101246279,1.367412853,0.932440919,2.030400322,0.212713488,DB0039910020772_,1.547809148,0.312920526,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,zoledronic acid,DB00399
,43866,DB00537,10020772,58,7499,57,4241,0.003386152,0.575521992,0.391507264,0.846197654,0.014914636,DB0053710020772_,4.205412244,-0.552477838,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ciprofloxacin,DB00537
,43869,DB01137,10020772,87,7685,49,5544,0.189944459,1.280838597,0.890758694,1.860098465,0.336423308,DB0113710020772_,1.089385065,0.247515017,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,levofloxacin,DB01137
,43893,DB00186,10020937,213,16688,69,9939,5.52536672732243e-06,1.838482006,1.393443756,2.451193154,6.45485619678534e-05,DB0018610020937_,9.648092719,0.608940234,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,43894,DB00188,10020937,130,7756,111,8717,0.037423,1.316255528,1.011867614,1.714592839,0.100425069,DB0018810020937_,2.298343417,0.274790984,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,43895,DB00254,10020937,61,5874,24,3364,0.140487156,1.455539705,0.892250875,2.446094597,0.270508014,DB0025410020937_,1.307453556,0.375376763,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,doxycycline,DB00254
,43898,DB00399,10020937,142,6850,50,4948,5.97113776090172e-06,2.051304558,1.472960441,2.897494784,6.90047729370419e-05,DB0039910020937_,9.581334883,0.718475961,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,zoledronic acid,DB00399
,43900,DB00537,10020937,93,7464,54,4244,0.93126367,0.979239462,0.691299608,1.399036353,0.972324352,DB0053710020937_,0.028065835,-0.020979068,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,43901,DB00682,10020937,162,19297,102,16262,0.021741574,1.338427408,1.037364296,1.733489999,0.066032386,DB0068210020937_,2.717609963,0.291495348,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,43903,DB01041,10020937,58,2987,50,3068,0.383462231,1.191420723,0.799165822,1.781708908,0.553488393,DB0104110020937_,0.591514498,0.17514648,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,thalidomide,DB01041
,43904,DB01067,10020937,48,4313,24,4799,0.001246229,2.225188976,1.333852532,3.805113357,0.006595707,DB0106710020937_,5.021336366,0.799841845,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,glipizide,DB01067
,43905,DB01137,10020937,90,7682,63,5530,0.934350638,1.028378364,0.735592001,1.445218238,0.97479745,DB0113710020937_,0.025525574,0.027983158,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,43906,DB11089,10020937,109,10066,77,8330,0.300747074,1.171439826,0.865660703,1.591815408,0.46701346,DB1108910020937_,0.761397199,0.158233613,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,docusate,DB11089
,43930,DB00186,10021015,112,16789,56,9952,0.336675171,1.185568922,0.851863496,1.66616934,0.505700555,DB0018610021015_,0.681810573,0.170222762,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,lorazepam,DB00186
,43931,DB00188,10021015,36,7850,25,8803,0.07195691,1.614755967,0.941960898,2.809025272,0.164697612,DB0018810021015_,1.80364414,0.479183841,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,bortezomib,DB00188
,43932,DB00264,10021015,111,29496,85,24807,0.565659889,1.098247449,0.820099181,1.475231559,0.717238987,DB0026410021015_,0.332346178,0.093715681,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,43935,DB00399,10021015,54,6938,17,4981,0.002336499,2.280322985,1.299899209,4.20126204,0.011044848,DB0039910021015_,4.505791185,0.824317093,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,zoledronic acid,DB00399
,43937,DB00682,10021015,66,19393,39,16325,0.09490656,1.424565502,0.944157048,2.175332615,0.203062183,DB0068210021015_,1.594243027,0.353866856,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,43963,DB00254,10021097,52,5883,54,3334,0.002195639,0.545792784,0.364703764,0.816020889,0.010495066,DB0025410021097_,4.556850057,-0.605515892,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,doxycycline,DB00254
,43964,DB00319,10021097,80,1312,94,1759,0.431233976,1.140973141,0.828631553,1.56802763,0.599653112,DB0031910021097_,0.511403938,0.131881531,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,piperacillin,DB00319
,43965,DB00332,10021097,46,2638,48,1608,0.013114826,0.584254158,0.379349753,0.898867959,0.04420095,DB0033210021097_,3.119008993,-0.537419189,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ipratropium,DB00332
,43966,DB00399,10021097,90,6902,68,4930,0.745643017,0.945399123,0.680801756,1.317982306,0.85479359,DB0039910021097_,0.156895254,-0.056148088,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,zoledronic acid,DB00399
,43967,DB00480,10021097,590,66838,710,66952,0.001103832,0.832405572,0.744664454,0.930262914,0.005971846,DB0048010021097_,5.12069918,-0.18343549,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,lenalidomide,DB00480
,43968,DB00537,10021097,93,7464,80,4218,0.006698228,0.656997932,0.480756561,0.899460558,0.02586498,DB0053710021097_,3.654865362,-0.420074408,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ciprofloxacin,DB00537
,43970,DB01041,10021097,22,3023,43,3075,0.012438477,0.520484842,0.295751427,0.892011337,0.042355757,DB0104110021097_,3.161650921,-0.652994514,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,thalidomide,DB01041
,43971,DB11089,10021097,239,9936,236,8171,0.049928684,0.832827786,0.691092603,1.003682227,0.124874018,DB1108910021097_,2.080449909,-0.182928398,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,docusate,DB11089
,43982,DB00480,10021639,35,67393,33,67629,0.809596792,1.064347483,0.642328287,1.767252785,0.897389743,DB0048010021639_,0.108265015,0.06236192,NA,10021639,Incontinence,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,43994,DB00254,10021789,79,5856,39,3349,0.500697853,1.158457607,0.777795031,1.750780807,0.662264087,DB0025410021789_,0.41209088,0.147089471,NA,10021789,Infection,10021881,Infections and infestations,Infec,doxycycline,DB00254
,43995,DB00264,10021789,234,29373,200,24692,0.884650433,0.983541266,0.810236067,1.19481747,0.951939928,DB0026410021789_,0.049253347,-0.016595683,NA,10021789,Infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,43997,DB00332,10021789,37,2647,14,1642,0.146285193,1.639254836,0.862421465,3.293333645,0.278800402,DB0033210021789_,1.277259159,0.49424177,NA,10021789,Infection,10021881,Infections and infestations,Infec,ipratropium,DB00332
,43998,DB00399,10021789,59,6933,49,4949,0.434827123,0.859526283,0.577386524,1.284513064,0.603279456,DB0039910021789_,0.505374747,-0.151373876,NA,10021789,Infection,10021881,Infections and infestations,Infec,zoledronic acid,DB00399
,43999,DB00480,10021789,538,66890,623,67039,0.015614451,0.865488657,0.769369496,0.973375572,0.050880288,DB0048010021789_,2.978279704,-0.14446101,NA,10021789,Infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,44003,DB01067,10021789,41,4320,33,4790,0.19847981,1.377538819,0.848068695,2.25306479,0.347247192,DB0106710021789_,1.057718383,0.320298442,NA,10021789,Infection,10021881,Infections and infestations,Infec,glipizide,DB01067
,44004,DB01234,10021789,249,31376,284,32604,0.296534606,0.911093048,0.764855649,1.084705825,0.462398013,DB0123410021789_,0.771329258,-0.093110249,NA,10021789,Infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,44005,DB11089,10021789,89,10086,84,8323,0.398994266,0.874330131,0.640574399,1.194196833,0.568878755,DB1108910021789_,0.564087952,-0.13429725,NA,10021789,Infection,10021881,Infections and infestations,Infec,docusate,DB11089
,44012,DB00480,10022116,28,67400,38,67624,0.26774201,0.739295218,0.436952488,1.236920938,0.43011849,DB0048010022116_,0.843694551,-0.302057955,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,44014,DB00682,10022116,28,19431,30,16334,0.359490529,0.784583744,0.451464131,1.359622125,0.529193728,DB0068210022116_,0.636400698,-0.242601964,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,44019,DB11089,10022116,43,10132,16,8391,0.005565864,2.225563885,1.227300611,4.235675337,0.022289745,DB1108910022116_,3.803628589,0.800010315,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,44051,DB00480,10024453,44,67384,29,67633,0.079935795,1.522834863,0.931583694,2.524404204,0.178317269,DB0048010024453_,1.724190907,0.420573639,NA,10024453,Ligament sprain,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,44063,DB00186,10025082,38,16863,16,9992,0.263710483,1.407264967,0.765712733,2.704818186,0.425566678,DB0018610025082_,0.854333639,0.341648081,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,44069,DB00480,10025082,62,67366,90,67572,0.028140301,0.691000576,0.491664238,0.965745815,0.080556287,DB0048010025082_,2.518799127,-0.369614622,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,44073,DB00999,10025082,46,21384,22,12217,0.53032679,1.194530055,0.703744032,2.086204009,0.687392853,DB0099910025082_,0.374849311,0.177752848,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,44077,DB01234,10025082,39,31586,37,32851,0.731216857,1.096256583,0.680817367,1.768105613,0.843659931,DB0123410025082_,0.170005791,0.091901269,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,44091,DB00682,10027141,45,19414,155,16209,5.35775739772506e-20,0.242393567,0.169836154,0.340037761,5.54443516532296e-18,DB0068210027141_,39.73373692,-1.417192562,male,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,44137,DB01234,10027452,39,31586,17,32871,0.001998776,2.38749532,1.318982055,4.501615695,0.009717529,DB0123410027452_,4.633823931,0.870244833,NA,10027452,Metastases to bone,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,44164,DB00264,10027727,30,29577,21,24871,0.57511326,1.201266475,0.66506325,2.208181257,0.724646567,DB0026410027727_,0.322071237,0.183376396,NA,10027727,Mitral valve incompetence,10007541,Cardiac disorders,Card,metoprolol,DB00264
,44223,DB00178,10028813,92,1345,54,1626,2.80301882738514e-05,2.059190085,1.44366778,2.96106535,0.00026748,DB0017810028813_,8.22646598,0.722312743,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ramipril,DB00178
,44224,DB00319,10028813,68,1324,40,1813,2.63219378213979e-05,2.327274982,1.541356574,3.554148099,0.000252416,DB0031910028813_,8.284432212,0.844698047,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,piperacillin,DB00319
,44225,DB00332,10028813,144,2540,60,1596,0.009604842,1.507894851,1.100552171,2.087394781,0.034475388,DB0033210028813_,3.367509606,0.41071454,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ipratropium,DB00332
,44226,DB00502,10028813,30,1364,33,1839,0.442186903,1.225588903,0.71817785,2.084185437,0.610301281,DB0050210028813_,0.49380254,0.203421466,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,haloperidol,DB00502
,44228,DB01041,10028813,47,2998,50,3068,0.918557316,0.961944078,0.629852215,1.466991129,0.963997407,DB0104110028813_,0.036666674,-0.038798961,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,thalidomide,DB01041
,44231,DB00254,10029331,68,5867,45,3343,0.433088382,0.861046627,0.580720763,1.287530735,0.601533891,DB0025410029331_,0.508272401,-0.149606622,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,doxycycline,DB00254
,44232,DB00264,10029331,308,29299,265,24627,0.800368001,0.976924644,0.825530551,1.156726582,0.892050498,DB0026410029331_,0.114232536,-0.02334576,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,44233,DB00295,10029331,96,14567,91,9511,0.013036664,0.688816863,0.511008851,0.929012841,0.043982634,DB0029510029331_,3.123960394,-0.372779845,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,morphine,DB00295
,44237,DB00537,10029331,144,7413,120,4178,0.002279742,0.676377809,0.525511799,0.871758444,0.010826792,DB0053710029331_,4.525731477,-0.39100347,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,44239,DB01067,10029331,44,4317,33,4790,0.108103339,1.479347565,0.918846102,2.402913767,0.223195056,DB0106710029331_,1.4997092,0.391601156,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,glipizide,DB01067
,44245,DB00264,10030041,48,29559,35,24857,0.581834465,1.153268275,0.730319189,1.837644345,0.7300706,DB0026410030041_,0.314614038,0.14259989,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,metoprolol,DB00264
,44250,DB00480,10030041,106,67322,68,67594,0.003868266,1.565107376,1.143245035,2.155105432,0.016599031,DB0048010030041_,4.098410948,0.447954433,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,lenalidomide,DB00480
,44253,DB00682,10030041,40,19419,22,16342,0.12549476,1.53006389,0.887342483,2.704245549,0.249367233,DB0068210030041_,1.388828638,0.425309493,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,warfarin,DB00682
,44255,DB00999,10030041,51,21379,19,12220,0.134904406,1.534246335,0.889855515,2.753081854,0.26248524,DB0099910030041_,1.337560428,0.428039274,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,hydrochlorothiazide,DB00999
,44259,DB01234,10030041,89,31536,35,32853,3.1923710624719e-07,2.649069829,1.772385381,4.038254865,5.1637829770507e-06,DB0123410030041_,12.17384111,0.974208571,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,dexamethasone,DB01234
,44263,DB00188,10030124,127,7759,96,8732,0.003618979,1.488765517,1.131008983,1.965043082,0.015738725,DB0018810030124_,4.151631038,0.397947265,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,44264,DB00254,10030124,41,5894,33,3355,0.14618756,0.707269137,0.435360592,1.156899694,0.27867716,DB0025410030124_,1.277701299,-0.34634401,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,44266,DB00332,10030124,42,2642,25,1631,1,1.0371174,0.614924872,1.782980147,1,DB0033210030124_,0,0.036445134,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,ipratropium,DB00332
,44267,DB00399,10030124,101,6891,73,4925,0.938444895,0.988830832,0.72280637,1.358350552,0.978144719,DB0039910030124_,0.022097646,-0.011232011,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,44268,DB00480,10030124,612,66816,539,67123,0.028441592,1.14065111,1.013796394,1.283733987,0.081246237,DB0048010030124_,2.510270775,0.131599249,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,44271,DB01067,10030124,67,4294,46,4777,0.013441434,1.620254506,1.094130243,2.417736724,0.045050441,DB0106710030124_,3.099972504,0.482583239,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,44275,DB00188,10031127,14,7872,48,8780,9.73175335395803e-05,0.325348929,0.165509671,0.600460498,0.000778215,DB0018810031127_,7.158508245,-1.122857045,male,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,bortezomib,DB00188
,44277,DB00264,10031127,47,29560,89,24803,3.91580299730055e-06,0.443109855,0.304225517,0.638171434,4.76844483595297e-05,DB0026410031127_,9.950905243,-0.81393756,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,44282,DB00480,10031127,24,67404,87,67575,1.40579552428473e-09,0.276588115,0.16822447,0.438820869,3.78405892020728e-08,DB0048010031127_,17.08988352,-1.285225829,male,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,lenalidomide,DB00480
,44285,DB00682,10031127,17,19442,40,16324,0.000256187,0.356850699,0.189598382,0.644215776,0.001772075,DB0068210031127_,6.335603943,-1.030437794,male,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,warfarin,DB00682
,44291,DB01234,10031127,22,31603,76,32812,7.7197429287062e-08,0.300577595,0.177954041,0.488560896,1.43249871430316e-06,DB0123410031127_,13.45609029,-1.202049339,male,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,dexamethasone,DB01234
,44298,DB00264,10031161,89,29518,32,24860,2.10605401861735e-05,2.34226389,1.547319766,3.628460792,0.0002087,DB0026410031161_,8.474613559,0.851117936,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,44299,DB00295,10031161,34,14629,16,9586,0.312396114,1.392438092,0.747401435,2.70313798,0.47991634,DB0029510031161_,0.734143481,0.331056233,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,44303,DB00480,10031161,62,67366,32,67630,0.001885896,1.945072015,1.249824272,3.080685015,0.0092751,DB0048010031161_,4.680421888,0.665299002,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,44306,DB00682,10031161,39,19420,19,16345,0.048809718,1.727583883,0.974142478,3.166579394,0.122793302,DB0068210031161_,2.097252811,0.546723833,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,44308,DB00999,10031161,134,21296,29,12210,2.8960003138838e-07,2.649182654,1.761558179,4.10967067,4.74572121262068e-06,DB0099910031161_,12.25826714,0.97425116,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,44312,DB01234,10031161,44,31581,14,32874,3.49328664689387e-05,3.27168552,1.759126874,6.464924722,0.000324227,DB0123410031161_,8.034067181,1.185305302,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,44336,DB00178,10033371,52,1385,31,1649,0.00246018,1.996693843,1.248006192,3.242378799,0.011520726,DB0017810033371_,4.463607604,0.691492734,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ramipril,DB00178
,44338,DB00332,10033371,99,2585,36,1620,0.005146596,1.723201141,1.159242477,2.612170654,0.020936049,DB0033210033371_,3.866282787,0.54418369,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ipratropium,DB00332
,44341,DB01041,10033371,31,3014,26,3092,0.50652263,1.223121422,0.700927307,2.150209681,0.667292829,DB0104110033371_,0.404526305,0.201406134,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,thalidomide,DB01041
,44343,DB00178,10033425,37,1400,25,1655,0.038734465,1.749234989,1.019529316,3.047890411,0.103106416,DB0017810033425_,2.271993656,0.559178543,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ramipril,DB00178
,44344,DB00186,10033425,352,16549,111,9897,1.06623474024991e-09,1.896449975,1.525526371,2.372811299,2.94700106703143e-08,DB0018610033425_,17.33989268,0.639983704,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,44345,DB00188,10033425,111,7775,97,8731,0.080431189,1.285009708,0.967987351,1.708270619,0.17913352,DB0018810033425_,1.719623828,0.250766273,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,bortezomib,DB00188
,44346,DB00254,10033425,106,5829,30,3358,0.000419865,2.035360116,1.342736322,3.170332831,0.002666381,DB0025410033425_,5.92703314,0.710672764,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,doxycycline,DB00254
,44347,DB00264,10033425,696,28911,351,24541,7.8918012668687e-16,1.683161785,1.476616253,1.921273149,5.34628856442381e-14,DB0026410033425_,30.55978871,0.52067404,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,44349,DB00332,10033425,66,2618,19,1637,0.002194346,2.171696804,1.281890976,3.846856163,0.010491749,DB0033210033425_,4.55716618,0.775508799,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ipratropium,DB00332
,44350,DB00537,10033425,167,7390,68,4230,0.01963591,1.405696498,1.051349204,1.897049751,0.060921848,DB0053710033425_,2.798163417,0.340532908,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ciprofloxacin,DB00537
,44352,DB01041,10033425,50,2995,28,3090,0.011697012,1.842164548,1.134102806,3.047559676,0.040337963,DB0104110033425_,3.210462247,0.610941265,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,thalidomide,DB01041
,44355,DB00264,10033661,117,29490,139,24753,0.00564783,0.706530474,0.547360793,0.910629936,0.022560535,DB0026410033661_,3.791553139,-0.347388944,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,metoprolol,DB00264
,44356,DB00295,10033661,63,14600,57,9545,0.076173031,0.722609708,0.496447446,1.053764809,0.171752788,DB0029510033661_,1.761699113,-0.324886025,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,morphine,DB00295
,44357,DB00319,10033661,22,1370,31,1822,0.889357517,0.943825614,0.518197491,1.691965878,0.954017276,DB0031910033661_,0.047073498,-0.057813861,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,piperacillin,DB00319
,44360,DB00537,10033661,24,7533,33,4265,0.001256266,0.411793648,0.232543227,0.719287597,0.006636045,DB0053710033661_,5.015239147,-0.887232909,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,ciprofloxacin,DB00537
,44362,DB00999,10033661,48,21382,40,12199,0.076899711,0.684667462,0.440323002,1.069627071,0.173020236,DB0099910033661_,1.754346723,-0.378822015,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,hydrochlorothiazide,DB00999
,44366,DB00186,10033775,221,16680,81,9927,0.000153603,1.623759286,1.251689212,2.123990008,0.001150929,DB0018610033775_,6.767185406,0.484744008,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,44367,DB00188,10033775,96,7790,86,8742,0.135794967,1.252675917,0.92499804,1.698647273,0.263792086,DB0018810033775_,1.332594041,0.225281997,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,44368,DB00254,10033775,36,5899,25,3363,0.504508048,0.820967287,0.478443964,1.429418652,0.665528797,DB0025410033775_,0.40717337,-0.197272015,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,doxycycline,DB00254
,44369,DB00295,10033775,99,14564,54,9548,0.319641357,1.201875728,0.853286469,1.708773399,0.487823652,DB0029510033775_,0.717801307,0.183883443,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,morphine,DB00295
,44372,DB00399,10033775,103,6889,37,4961,0.000191607,2.004575374,1.36188565,3.008917175,0.001389191,DB0039910033775_,6.57903404,0.695432255,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,zoledronic acid,DB00399
,44373,DB00480,10033775,538,66890,386,67276,4.16433113198908e-07,1.401815726,1.22716531,1.602517078,6.56428448601696e-06,DB0048010033775_,11.93386705,0.337768343,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,44375,DB00537,10033775,80,7477,46,4252,1,0.989001782,0.678321971,1.456956041,1,DB0053710033775_,0,-0.011059146,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,44376,DB00682,10033775,125,19334,77,16287,0.033425998,1.367521511,1.020515559,1.842400519,0.092195302,DB0068210033775_,2.383846108,0.312999986,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,44378,DB00999,10033775,281,21149,87,12152,1.90820796295915e-07,1.85582618,1.452665724,2.39099273,3.25590693322826e-06,DB0099910033775_,12.63503969,0.618329977,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,44379,DB01041,10033775,47,2998,28,3090,0.026636346,1.729918257,1.057985472,2.876890566,0.077184033,DB0104110033775_,2.561562671,0.548074157,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,thalidomide,DB01041
,44380,DB01067,10033775,43,4318,25,4798,0.010196793,1.911048907,1.138970448,3.27083545,0.036119223,DB0106710033775_,3.320930057,0.647652257,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,glipizide,DB01067
,44381,DB11089,10033775,99,10076,51,8356,0.006385047,1.60976857,1.135507232,2.306315501,0.024884123,DB1108910033775_,3.693525295,0.476090423,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,docusate,DB11089
,44392,DB00480,10034156,46,67382,56,67606,0.372836124,0.824161714,0.5455063,1.239667926,0.542560416,DB0048010034156_,0.611455833,-0.193388513,NA,10034156,Pathological fracture,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,44401,DB01234,10034156,37,31588,36,32852,0.815358192,1.068937997,0.656883262,1.740915945,0.900945438,DB0123410034156_,0.104310581,0.066665629,NA,10034156,Pathological fracture,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,44426,DB00254,10035226,21,5914,30,3358,0.001166599,0.397503117,0.21595905,0.719111574,0.006257329,DB0025410035226_,5.074001806,-0.922552502,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,doxycycline,DB00254
,44429,DB00537,10035226,26,7531,36,4262,0.000499893,0.40875529,0.236608926,0.697126462,0.003091689,DB0053710035226_,5.779037639,-0.894638614,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ciprofloxacin,DB00537
,44431,DB01067,10035226,24,4337,40,4783,0.131298511,0.661733059,0.380896466,1.126932335,0.257618136,DB0106710035226_,1.356276882,-0.412893038,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,glipizide,DB01067
,44434,DB00295,10035598,86,14577,44,9558,0.207927464,1.281558382,0.88033208,1.889186269,0.358754496,DB0029510035598_,1.025116979,0.248076824,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,44435,DB00319,10035598,30,1362,24,1829,0.070807754,1.678290532,0.9437734,3.014701278,0.162719165,DB0031910035598_,1.815729476,0.517775735,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,piperacillin,DB00319
,44437,DB00399,10035598,41,6951,23,4975,0.375924752,1.27583046,0.746692316,2.230223465,0.545725685,DB0039910035598_,0.605638838,0.243597308,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zoledronic acid,DB00399
,44438,DB00480,10035598,138,67290,188,67474,0.006523104,0.736054095,0.586377177,0.922032879,0.025311455,DB0048010035598_,3.67649823,-0.306451665,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,44439,DB00537,10035598,31,7526,32,4266,0.018081191,0.549178298,0.323615248,0.930797667,0.057055756,DB0053710035598_,2.863726316,-0.599332121,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ciprofloxacin,DB00537
,44442,DB01234,10035598,157,31468,188,32700,0.195339114,0.867804017,0.697177009,1.079042259,0.343444055,DB0123410035598_,1.068731049,-0.141789377,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,44443,DB11089,10035598,113,10062,90,8317,0.831704401,1.037815375,0.778573397,1.386762298,0.912067678,DB1108910035598_,0.092041083,0.037117903,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,44444,DB00178,10035664,41,1396,53,1627,0.67480492,0.901641618,0.580884596,1.390818799,0.802790166,DB0017810035664_,0.219661912,-0.103538158,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ramipril,DB00178
,44445,DB00319,10035664,66,1326,84,1769,0.800278167,1.048228943,0.741502315,1.476707029,0.892026021,DB0031910035664_,0.114259976,0.047102019,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,piperacillin,DB00319
,44446,DB00399,10035664,282,6710,297,4701,1.89867936240993e-06,0.665250863,0.560727435,0.789082661,2.52884656908766e-05,DB0039910035664_,10.58516217,-0.407591071,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,zoledronic acid,DB00399
,44447,DB00502,10035664,47,1347,42,1830,0.064145882,1.520081884,0.974851974,2.377020585,0.150912912,DB0050210035664_,1.891052352,0.418764204,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,haloperidol,DB00502
,44449,DB01041,10035664,118,2927,141,2977,0.227643011,0.851198441,0.657191654,1.100927003,0.382922503,DB0104110035664_,0.959922652,-0.161109992,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,thalidomide,DB01041
,44473,DB00186,10036790,66,16835,25,9983,0.064208245,1.565470566,0.973756327,2.591345874,0.15101908,DB0018610036790_,1.890349093,0.44818646,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,44475,DB00264,10036790,112,29495,82,24810,0.348886085,1.148893495,0.855957272,1.547636617,0.518398573,DB0026410036790_,0.657010888,0.138799301,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,44476,DB00295,10036790,35,14628,20,9582,0.680395231,1.146357904,0.643269168,2.096989166,0.806629621,DB0029510036790_,0.214890673,0.136589876,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,44478,DB00332,10036790,33,2651,23,1633,0.678943138,0.883845784,0.501542174,1.582392579,0.805653035,DB0033210036790_,0.216102106,-0.123472685,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipratropium,DB00332
,44481,DB00537,10036790,30,7527,20,4278,0.658611171,0.852549256,0.467727305,1.586056269,0.79153192,DB0053710036790_,0.233785072,-0.159524294,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ciprofloxacin,DB00537
,44483,DB00999,10036790,80,21350,35,12204,0.207107982,1.306544667,0.867315621,2.004622297,0.357782085,DB0099910036790_,1.027831178,0.267385994,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,44485,DB01137,10036790,41,7731,31,5562,0.904767662,0.951548661,0.58151153,1.571496733,0.957650673,DB0113710036790_,0.043272209,-0.049664453,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,44486,DB01234,10036790,81,31544,65,32823,0.135539794,1.296671561,0.923641304,1.826514722,0.263491124,DB0123410036790_,1.333735596,0.259800643,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,44487,DB11089,10036790,44,10131,36,8371,1,1.009892551,0.634647187,1.61647426,1,DB1108910036790_,0,0.00984394,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,44512,DB00264,10037368,34,29573,19,24873,0.168685728,1.505060266,0.834241968,2.79387476,0.309091401,DB0026410037368_,1.174118251,0.408832941,NA,10037368,Pulmonary congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,44519,DB00682,10037368,33,19426,18,16346,0.15966993,1.542635602,0.84337389,2.911047123,0.297022229,DB0068210037368_,1.213948297,0.433492384,NA,10037368,Pulmonary congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,44560,DB00682,10037833,36,19423,15,16349,0.023616675,2.020087468,1.078268631,3.97289737,0.07032961,DB0068210037833_,2.65456238,0.703140812,NA,10037833,Rales,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,44567,DB00080,10037844,29,611,30,883,0.225813686,1.396666867,0.799842892,2.435713196,0.380652546,DB0008010037844_,0.965868274,0.334088588,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,daptomycin,DB00080
,44568,DB00178,10037844,37,1400,45,1635,0.910826464,0.960242686,0.600555398,1.52693206,0.9598506,DB0017810037844_,0.040977631,-0.040569229,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ramipril,DB00178
,44569,DB00295,10037844,370,14293,202,9400,0.037737373,1.204601342,1.009991346,1.44008591,0.101077785,DB0029510037844_,2.291864912,0.186148675,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,morphine,DB00295
,44570,DB00332,10037844,66,2618,44,1612,0.691804669,0.923623808,0.617873145,1.392349838,0.814220538,DB0033210037844_,0.205524019,-0.079450424,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ipratropium,DB00332
,44571,DB00399,10037844,223,6769,158,4840,0.957914103,1.009179492,0.816569398,1.249590979,0.995582222,DB0039910037844_,0.004427565,0.009137617,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,zoledronic acid,DB00399
,44573,DB00537,10037844,278,7279,130,4168,0.066506063,1.224436525,0.987120683,1.525272598,0.155063487,DB0053710037844_,1.863920654,0.202480758,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ciprofloxacin,DB00537
,44575,DB01041,10037844,54,2991,58,3060,0.848913739,0.952505056,0.642764874,1.409499351,0.924728456,DB0104110037844_,0.078255146,-0.048659864,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,thalidomide,DB01041
,44627,DB00480,10039227,39,67389,45,67617,0.585577232,0.869600432,0.551439165,1.365890027,0.733042313,DB0048010039227_,0.310551854,-0.139721446,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,44691,DB00999,10040741,37,21393,23,12216,0.788622589,0.918613863,0.531325348,1.620099345,0.885530673,DB0099910040741_,0.121568183,-0.084889416,NA,10040741,Sinus bradycardia,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,44708,DB00999,10040808,31,21399,26,12213,0.167850334,0.680518842,0.390797713,1.193807197,0.30793551,DB0099910040808_,1.177864901,-0.384899768,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,hydrochlorothiazide,DB00999
,44718,DB00264,10040831,41,29566,36,24856,0.908997755,0.9574401,0.596693364,1.542372962,0.95913476,DB0026410040831_,0.041723693,-0.043492118,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,44722,DB00480,10040831,87,67341,86,67576,0.939471699,1.015159821,0.744650468,1.384168439,0.978949994,DB0048010040831_,0.021274716,0.015046059,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,44726,DB00999,10040831,68,21362,32,12207,0.405587256,1.214252358,0.786122064,1.911833025,0.575178812,DB0099910040831_,0.55307431,0.194128544,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,44730,DB01234,10040831,44,31581,33,32855,0.171378645,1.387107281,0.863052478,2.249228568,0.312746587,DB0123410040831_,1.162362043,0.327220486,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,44742,DB00480,10040880,23,67405,41,67621,0.032741357,0.562779036,0.322307177,0.960271069,0.0907143,DB0048010040880_,2.40004027,-0.574868204,NA,10040880,Skin irritation,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,44745,DB00682,10040880,39,19420,19,16345,0.048809718,1.727583883,0.974142478,3.166579394,0.122793302,DB0068210040880_,2.097252811,0.546723833,NA,10040880,Skin irritation,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,44755,DB00188,10041349,34,7852,39,8789,1,0.97582666,0.596884842,1.58825303,1,DB0018810041349_,0,-0.024470311,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,44756,DB00254,10041349,45,5890,21,3367,0.521208364,1.224975977,0.713273401,2.168830574,0.680064167,DB0025410041349_,0.385568122,0.202921233,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,doxycycline,DB00254
,44757,DB00295,10041349,187,14476,132,9470,0.526239049,0.926767461,0.736542824,1.168872512,0.68414238,DB0029510041349_,0.379589225,-0.076052596,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,morphine,DB00295
,44759,DB00332,10041349,34,2650,16,1640,0.464320711,1.315002261,0.703693715,2.559949235,0.631450223,DB0033210041349_,0.459736164,0.273838385,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ipratropium,DB00332
,44760,DB00399,10041349,55,6937,31,4967,0.323731819,1.270324758,0.802262452,2.044425706,0.492179471,DB0039910041349_,0.708911851,0.239272583,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,zoledronic acid,DB00399
,44761,DB00480,10041349,263,67165,230,67432,0.136424519,1.148021888,0.957823792,1.376765072,0.264691441,DB0048010041349_,1.329190506,0.138040364,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,44762,DB00537,10041349,43,7514,25,4273,1,0.978105335,0.583117724,1.673630246,1,DB0053710041349_,0,-0.02213791,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,44764,DB00999,10041349,258,21172,112,12127,0.014430887,1.319440203,1.051730872,1.664103601,0.047760748,DB0099910041349_,3.041551144,0.277207558,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,44765,DB01041,10041349,43,3002,34,3084,0.301980728,1.29919221,0.806881497,2.106965912,0.46829415,DB0104110041349_,0.758658654,0.261742694,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,thalidomide,DB01041
,44766,DB01137,10041349,55,7717,25,5568,0.06826644,1.587297239,0.971210532,2.66199387,0.158165127,DB0113710041349_,1.844115683,0.46203272,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,44767,DB01234,10041349,210,31415,166,32722,0.008285055,1.317681667,1.069226221,1.626084779,0.030620473,DB0123410041349_,3.486086443,0.275873879,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,44768,DB11089,10041349,127,10048,89,8318,0.242821005,1.181269315,0.892360206,1.569360003,0.401065107,DB1108910041349_,0.913631503,0.166589551,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,docusate,DB11089
,44821,DB00480,10041823,17,67411,37,67625,0.009065241,0.460922803,0.243351364,0.839378289,0.032920678,DB0048010041823_,3.413654314,-0.774524705,NA,10041823,Squamous cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,44834,DB00188,10042128,37,7849,26,8802,0.076376956,1.595802453,0.939684184,2.747373701,0.172116622,DB0018810042128_,1.759582997,0.467376715,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,44836,DB00295,10042128,75,14588,28,9574,0.011238314,1.757885845,1.124163396,2.821218964,0.039084024,DB0029510042128_,3.242041487,0.564111862,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,44839,DB00399,10042128,76,6916,23,4975,0.000134437,2.37679366,1.471720821,3.97784128,0.001025887,DB0039910042128_,6.882197331,0.865752378,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,44840,DB00480,10042128,356,67072,215,67447,2.80012935746433e-09,1.665054853,1.401319194,1.98221483,7.11812380666828e-08,DB0048010042128_,16.45803656,0.509858067,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,44843,DB00682,10042128,58,19401,31,16333,0.042862528,1.575076569,1.001026281,2.522020469,0.111443844,DB0068210042128_,2.194234454,0.454303887,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,44847,DB01137,10042128,34,7738,21,5572,0.681560815,1.165809942,0.656629388,2.116382862,0.807446975,DB0113710042128_,0.213877892,0.153416075,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,44848,DB11089,10042128,88,10087,45,8362,0.008550481,1.621086938,1.118056815,2.379254618,0.031404933,DB1108910042128_,3.460790305,0.483096874,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,44853,DB00264,10042209,88,29519,36,24856,0.000191259,2.058239036,1.381328491,3.124683572,0.001387673,DB0026410042209_,6.580126951,0.72185078,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,44858,DB00480,10042209,103,67325,43,67619,4.92671956010143e-07,2.405925651,1.669720387,3.519265353,7.6535947776162e-06,DB0048010042209_,11.78033511,0.877934716,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,44861,DB00682,10042209,64,19395,14,16350,4.94516316655735e-07,3.853497801,2.137129095,7.444622026,7.6798674147103e-06,DB0068210042209_,11.77690827,1.348981256,female,10042209,Stress,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,44866,DB01234,10042209,50,31575,18,32870,4.77291388574708e-05,2.891719869,1.657536773,5.26811082,0.000424483,DB0123410042209_,7.764637876,1.061851436,female,10042209,Stress,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,44870,DB00186,10042772,123,16778,62,9946,0.321483544,1.176067235,0.858838972,1.624532703,0.489768386,DB0018610042772_,0.713822682,0.16217602,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,44871,DB00188,10042772,79,7807,71,8757,0.188945615,1.248051974,0.892884338,1.747314272,0.335207579,DB0018810042772_,1.093005299,0.221583915,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,44873,DB00295,10042772,60,14603,43,9559,0.686634053,0.913388051,0.606652641,1.385593626,0.811001522,DB0029510042772_,0.209485348,-0.090594461,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,morphine,DB00295
,44876,DB00399,10042772,48,6944,18,4980,0.017306828,1.912336647,1.090629513,3.497328094,0.055170695,DB0039910042772_,2.89732335,0.64832587,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,zoledronic acid,DB00399
,44878,DB00537,10042772,39,7518,28,4270,0.372874825,0.791131968,0.473751872,1.336955765,0.542601715,DB0053710042772_,0.611379718,-0.234290489,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,44881,DB01067,10042772,28,4333,46,4777,0.102415526,0.671099182,0.403197295,1.098887395,0.214612518,DB0106710042772_,1.538921121,-0.39883834,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,glipizide,DB01067
,44882,DB01137,10042772,59,7713,35,5558,0.401910383,1.21470796,0.785166716,1.904444833,0.571672092,DB0113710042772_,0.559189718,0.194503686,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,44883,DB11089,10042772,93,10082,91,8316,0.264446867,0.842974607,0.623611659,1.13986925,0.426401614,DB1108910042772_,0.852373622,-0.170818443,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,docusate,DB11089
,44886,DB00254,10043554,21,5914,30,3358,0.001166599,0.397503117,0.21595905,0.719111574,0.006257329,DB0025410043554_,5.074001806,-0.922552502,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,doxycycline,DB00254
,44887,DB00264,10043554,182,29425,201,24691,0.007436192,0.759805657,0.617809605,0.933880416,0.028099528,DB0026410043554_,3.572002493,-0.274692593,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,metoprolol,DB00264
,44888,DB00295,10043554,82,14581,88,9514,0.001564079,0.608037321,0.443970716,0.831915089,0.00795584,DB0029510043554_,4.833849005,-0.497519016,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,morphine,DB00295
,44891,DB00537,10043554,61,7496,53,4245,0.024377099,0.651836549,0.442768318,0.962255083,0.072124275,DB0053710043554_,2.629364606,-0.42796144,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,ciprofloxacin,DB00537
,44893,DB00999,10043554,101,21329,62,12177,0.683353493,0.930038389,0.670729526,1.298469656,0.808568573,DB0099910043554_,0.212489788,-0.072529415,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,hydrochlorothiazide,DB00999
,44895,DB01067,10043554,15,4346,36,4787,0.010860982,0.459001297,0.233129814,0.860961471,0.038033695,DB0106710043554_,3.269282793,-0.778702244,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,glipizide,DB01067
,44896,DB11089,10043554,114,10061,111,8296,0.225419829,0.846865507,0.645213383,1.111818719,0.380232318,DB1108910043554_,0.966972849,-0.166213384,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,docusate,DB11089
,44907,DB00480,10044044,37,67391,17,67645,0.006359086,2.184650952,1.199641319,4.137863389,0.024806853,DB0048010044044_,3.696635324,0.781456068,NA,10044044,Tooth loss,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,44920,DB00188,10046306,33,7853,46,8782,0.367021021,0.802269288,0.496425693,1.283640309,0.536659763,DB0018810046306_,0.622390974,-0.220310957,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,bortezomib,DB00188
,44921,DB00254,10046306,55,5880,13,3375,0.003275528,2.428174258,1.307279901,4.852469601,0.014528728,DB0025410046306_,4.231627361,0.887139641,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,doxycycline,DB00254
,44922,DB00264,10046306,187,29420,96,24796,7.32475611047722e-05,1.64173968,1.276088664,2.123664706,0.000610017,DB0026410046306_,7.402024135,0.49575646,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,44923,DB00295,10046306,55,14608,37,9565,0.91518173,0.973306522,0.629563026,1.520173976,0.962125858,DB0029510046306_,0.038610007,-0.027056219,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,morphine,DB00295
,44925,DB00332,10046306,45,2639,15,1641,0.043764501,1.8652321,1.016559908,3.614318392,0.113117648,DB0033210046306_,2.179326871,0.623385496,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,ipratropium,DB00332
,44926,DB00399,10046306,57,6935,23,4975,0.022298318,1.777757288,1.07638952,3.028019526,0.067291766,DB0039910046306_,2.698717395,0.575352619,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,zoledronic acid,DB00399
,44927,DB00480,10046306,336,67092,215,67447,2.15363418244529e-07,1.571045247,1.319451609,1.873790221,3.6217706004846e-06,DB0048010046306_,12.52854754,0.45174116,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,44929,DB00537,10046306,64,7493,19,4279,0.01135588,1.923494882,1.135940157,3.404726396,0.039394135,DB0053710046306_,3.23413833,0.654143783,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,44931,DB00999,10046306,162,21268,40,12199,4.58233738998504e-07,2.322963692,1.633415052,3.373782425,7.17158310781523e-06,DB0099910046306_,11.84538413,0.842843824,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,44934,DB01137,10046306,89,7683,42,5551,0.0257424,1.53097236,1.047497066,2.269239408,0.075127849,DB0113710046306_,2.588563959,0.425903063,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,levofloxacin,DB01137
,44935,DB11089,10046306,78,10097,42,8365,0.026908462,1.538537593,1.042879535,2.297912175,0.077813842,DB1108910046306_,2.553435943,0.43083235,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,docusate,DB11089
,44940,DB00264,10046543,58,29549,36,24856,0.177702867,1.355223235,0.878755418,2.115639282,0.320926164,DB0026410046543_,1.1365442,0.30396619,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,44944,DB00480,10046543,59,67369,47,67615,0.24496277,1.259897971,0.844159269,1.889578513,0.403748128,DB0048010046543_,0.906964041,0.231030743,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,44951,DB01234,10046543,53,31572,41,32847,0.17931684,1.344874767,0.877541184,2.074356137,0.323019781,DB0123410046543_,1.130041718,0.296300899,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,dexamethasone,DB01234
,44953,DB00178,10046571,36,1401,14,1666,0.000267355,3.056772532,1.601165927,6.161906109,0.001837148,DB0017810046571_,6.299540964,1.117359631,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ramipril,DB00178
,44954,DB00254,10046571,97,5838,34,3354,0.013289179,1.63896723,1.095759105,2.505165833,0.044648313,DB0025410046571_,3.108938761,0.494066306,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,doxycycline,DB00254
,44956,DB00399,10046571,138,6854,43,4955,4.19170478265029e-07,2.319947231,1.633119957,3.354645158,6.60149551899118e-06,DB0039910046571_,11.92821434,0.84154444,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,zoledronic acid,DB00399
,44959,DB01041,10046571,48,2997,22,3096,0.001587239,2.253615518,1.33053051,3.930742296,0.008044071,DB0104110046571_,4.822820025,0.812535823,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,thalidomide,DB01041
,44961,DB00178,10047895,26,1411,34,1646,0.696556764,0.892113132,0.51137119,1.539670693,0.817457062,DB0017810047895_,0.201556901,-0.114162324,NA,10047895,Weight decreased,10022891,Investigations,Inv,ramipril,DB00178
,44962,DB00254,10047895,67,5868,62,3326,0.007265213,0.612516672,0.425945239,0.882104352,0.027564394,DB0025410047895_,3.591230423,-0.490179117,NA,10047895,Weight decreased,10022891,Investigations,Inv,doxycycline,DB00254
,44964,DB00332,10047895,50,2634,46,1610,0.055360938,0.66447693,0.433953011,1.019306342,0.134949667,DB0033210047895_,2.002853404,-0.408755119,NA,10047895,Weight decreased,10022891,Investigations,Inv,ipratropium,DB00332
,44966,DB00537,10047895,121,7436,82,4216,0.238610172,0.836650057,0.625174515,1.124292823,0.396309524,DB0053710047895_,0.925559747,-0.178349388,NA,10047895,Weight decreased,10022891,Investigations,Inv,ciprofloxacin,DB00537
,44968,DB01041,10047895,37,3008,32,3086,0.54533107,1.186198098,0.716873948,1.972526019,0.700091683,DB0104110047895_,0.356543976,0.170753317,NA,10047895,Weight decreased,10022891,Investigations,Inv,thalidomide,DB01041
,44969,DB11089,10047895,223,9952,192,8215,0.690024469,0.958722773,0.785150322,1.171623941,0.813015717,DB1108910047895_,0.207004838,-0.042153325,NA,10047895,Weight decreased,10022891,Investigations,Inv,docusate,DB11089
,44978,DB00537,10049119,60,7497,25,4273,0.213296774,1.367872583,0.843274705,2.280298913,0.365405229,DB0053710049119_,1.006748324,0.313256674,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,ciprofloxacin,DB00537
,45037,DB00480,10050031,77,67351,57,67605,0.084182772,1.355963679,0.950139107,1.945010121,0.185384062,DB0048010050031_,1.685325596,0.304512404,NA,10050031,Muscle strain,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,45053,DB00264,10050256,57,29550,31,24861,0.053763372,1.546926896,0.981701015,2.479854068,0.132059644,DB0026410050256_,2.024501613,0.436270315,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,45062,DB00999,10050256,38,21392,23,12216,0.894129109,0.943483668,0.547591313,1.659657687,0.955860142,DB0099910050256_,0.045143671,-0.058176224,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,45076,DB00480,10050296,47,67381,54,67608,0.550620076,0.873304033,0.577779017,1.315822623,0.704713266,DB0048010050296_,0.349964274,-0.135471521,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,45080,DB00999,10050296,37,21393,14,12225,0.243346983,1.510239275,0.797070815,3.025462741,0.40166884,DB0099910050296_,0.91212731,0.412268099,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,45109,DB00188,10050584,33,7853,29,8799,0.373321278,1.274986564,0.749809543,2.178852195,0.543055967,DB0018810050584_,0.610542895,0.24293564,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,bortezomib,DB00188
,45110,DB00264,10050584,256,29351,157,24735,0.001760221,1.374124334,1.121295695,1.688323764,0.00875365,DB0026410050584_,4.73828452,0.31781668,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,45111,DB00295,10050584,56,14607,21,9581,0.02678541,1.749074969,1.04168087,3.043487327,0.077517699,DB0029510050584_,2.557248996,0.559087059,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,45114,DB00399,10050584,59,6933,26,4972,0.046258127,1.627312182,1.008128763,2.69399708,0.118007945,DB0039910050584_,2.13700333,0.486929685,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,zoledronic acid,DB00399
,45116,DB00537,10050584,49,7508,23,4275,0.538870439,1.212994344,0.723907655,2.089255,0.694766738,DB0053710050584_,0.364179119,0.193091967,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,ciprofloxacin,DB00537
,45118,DB00999,10050584,210,21220,65,12174,6.97866370013953e-06,1.853472751,1.395784698,2.489619029,7.92201146008066e-05,DB0099910050584_,9.443280319,0.617061042,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,45120,DB01137,10050584,47,7725,30,5563,0.644448204,1.12823105,0.697775305,1.850132385,0.780476932,DB0113710050584_,0.247850094,0.120650964,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,levofloxacin,DB01137
,45121,DB11089,10050584,93,10082,38,8369,0.000191452,2.031435257,1.377283079,3.049720352,0.001388797,DB1108910050584_,6.579317289,0.708742566,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,45158,DB00264,10052428,38,29569,45,24847,0.123602593,0.709602314,0.448185598,1.118120478,0.246539243,DB0026410052428_,1.400234095,-0.343050588,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,45163,DB00480,10052428,73,67355,81,67581,0.572715608,0.90426541,0.649748426,1.256539069,0.722744059,DB0048010052428_,0.324700118,-0.100632367,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,45166,DB00682,10052428,49,19410,22,16342,0.016467458,1.875166848,1.112053446,3.258227166,0.053009264,DB0068210052428_,2.93728859,0.628697641,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,45168,DB00999,10052428,36,21394,17,12222,0.569815625,1.209728052,0.661831116,2.297823736,0.720631433,DB0099910052428_,0.32762746,0.190395584,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,45172,DB01234,10052428,40,31585,44,32844,0.827721585,0.945310378,0.600160666,1.485050386,0.909407368,DB0123410052428_,0.094962136,-0.056241963,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,45221,DB00264,10058267,31,29576,33,24859,0.380230213,0.789579613,0.467537263,1.330337564,0.550337744,DB0026410058267_,0.59722311,-0.236254611,NA,10058267,Troponin increased,10022891,Investigations,Inv,metoprolol,DB00264
,45304,DB00264,10061225,54,29553,51,24841,0.557850339,0.890004967,0.595407757,1.332007204,0.710901105,DB0026410061225_,0.341221952,-0.116528235,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,45310,DB00682,10061225,63,19396,44,16320,0.382065263,1.204739975,0.806346575,1.814100857,0.552169216,DB0068210061225_,0.593900729,0.186263755,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,45312,DB00999,10061225,47,21383,14,12225,0.032467037,1.919296423,1.038309566,3.776023786,0.090125259,DB0099910061225_,2.406554806,0.651958673,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,45316,DB01234,10061225,49,31576,50,32838,1,1.019170446,0.672853808,1.542997509,1,DB0123410061225_,0,0.018989008,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,45339,DB00178,10061428,22,1415,30,1650,0.674327677,0.855166744,0.46772435,1.540784577,0.802491104,DB0017810061428_,0.22003451,-0.156458807,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ramipril,DB00178
,45340,DB00188,10061428,106,7780,159,8669,0.018447819,0.742859661,0.574255162,0.957731411,0.057960343,DB0018810061428_,2.847996238,-0.297248134,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,bortezomib,DB00188
,45342,DB00332,10061428,33,2651,30,1626,0.150013251,0.674774572,0.397306962,1.150122964,0.283941694,DB0033210061428_,1.258986366,-0.393376612,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ipratropium,DB00332
,45343,DB00399,10061428,198,6794,135,4863,0.69336814,1.049811933,0.836548884,1.320629839,0.815334924,DB0039910061428_,0.204156301,0.048611037,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,zoledronic acid,DB00399
,45345,DB00537,10061428,109,7448,77,4221,0.144625309,0.802281548,0.592223527,1.091257616,0.276495877,DB0053710061428_,1.285559371,-0.220295675,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ciprofloxacin,DB00537
,45347,DB01041,10061428,23,3022,42,3076,0.024707791,0.557459101,0.319152408,0.951041277,0.072855875,DB0104110061428_,2.619272108,-0.58436614,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,thalidomide,DB01041
,45348,DB01137,10061428,115,7657,115,5478,0.012540014,0.715453611,0.546328719,0.93696336,0.04264643,DB0113710061428_,3.154811721,-0.334838517,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,levofloxacin,DB01137
,45349,DB11089,10061428,216,9959,198,8209,0.294558563,0.899219968,0.736357199,1.098582148,0.460395541,DB1108910061428_,0.775669286,-0.106227594,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,45380,DB00480,10061728,64,67364,45,67617,0.069016696,1.427553366,0.959739621,2.139401892,0.159551791,DB0048010061728_,1.835386702,0.355962046,NA,10061728,Bone lesion,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,45389,DB01234,10061728,40,31585,36,32852,0.566889822,1.155678505,0.717919055,1.866344286,0.71815789,DB0123410061728_,0.331065832,0.144687622,NA,10061728,Bone lesion,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,45414,DB00186,10062060,35,16866,18,9990,0.671929043,1.15174663,0.634471177,2.161317102,0.800891278,DB0018610062060_,0.222030074,0.141279599,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,lorazepam,DB00186
,45417,DB00264,10062060,48,29559,39,24853,0.914497187,1.034827017,0.663832582,1.622170739,0.961752398,DB0026410062060_,0.038998244,0.03423428,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,45503,DB00999,10067585,36,21394,21,12218,1,0.979009115,0.556058834,1.765812562,1,DB0099910067585_,0,-0.021214326,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,45573,DB00181,10002948,43,9813,16,5855,0.107767942,1.603471279,0.884032873,3.052521519,0.222712505,DB0018110002948_,1.501873553,0.472170829,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,45574,DB06413,10003549,41,1515,22,652,0.406331731,0.802150166,0.462493337,1.426009972,0.575935159,DB0641310003549_,0.551760196,-0.220459449,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,armodafinil,DB06413
,45575,DB06413,10022437,56,1500,17,657,0.242960946,1.44261779,0.818550224,2.669300636,0.40124582,DB0641310022437_,0.913181022,0.366459373,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,armodafinil,DB06413
,45580,DB06413,10047895,61,1495,29,645,0.725288344,0.907552041,0.568092116,1.479612827,0.838945789,DB0641310047895_,0.175609188,-0.097004369,NA,10047895,Weight decreased,10022891,Investigations,Inv,armodafinil,DB06413
,45583,DB09072,10058920,56,6415,27,2508,0.390977054,0.810868433,0.502396258,1.338523633,0.560839983,DB0907210058920_,0.578319649,-0.209649466,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,45586,DB00230,10013754,261,19413,102,8549,0.329750385,1.126832854,0.891656596,1.433003312,0.498389331,DB0023010013754_,0.696373718,0.119410913,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,45587,DB00230,10040979,63,19611,29,8622,0.821422434,0.95510647,0.605556648,1.53933178,0.904850436,DB0023010040979_,0.099985613,-0.045932458,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,45589,DB01156,10040979,53,13569,17,6311,0.199690345,1.45001954,0.825645583,2.673573117,0.348692003,DB0115610040979_,1.053566259,0.371577033,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,45590,DB00230,10058920,105,19569,23,8628,0.001446721,2.012768083,1.271451109,3.315237287,0.007464338,DB0023010058920_,4.897618505,0.699510931,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,45592,DB01156,10058920,47,13575,10,6318,0.021967697,2.187374676,1.08990247,4.858672606,0.066561445,DB0115610058920_,2.709629773,0.782702047,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,45594,DB00422,10003549,61,3374,31,2918,0.015467832,1.701657311,1.083664211,2.721314014,0.050487019,DB0042210003549_,2.98603903,0.531602665,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,45603,DB00316,10013578,41,65433,26,36927,0.702866472,0.889938098,0.531407736,1.515548804,0.821706817,DB0031610013578_,0.196371618,-0.116603371,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,45606,DB00422,10017577,39,3396,28,2921,0.538374488,1.198003135,0.716563692,2.026891874,0.69428888,DB0042210017577_,0.364867151,0.180656117,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,45608,DB00316,10019465,77,65397,44,36909,1,0.987667622,0.673154306,1.46511483,1,DB0031610019465_,0,-0.012409053,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,45612,DB00422,10028372,36,3399,16,2933,0.025706712,1.941298853,1.047675327,3.754760889,0.075048695,DB0042210028372_,2.589618115,0.663357261,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,methylphenidate,DB00422
,45613,DB00422,10033371,110,3325,34,2915,2.27205237413957e-08,2.835774294,1.907958821,4.312319558,4.70243280742193e-07,DB0042210033371_,14.57001566,1.04231502,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,45614,DB00316,10034754,39,65435,16,36937,0.326579991,1.375925131,0.751254271,2.637760299,0.495035038,DB0031610034754_,0.703126735,0.319126327,NA,10034754,Petechiae,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,45617,DB00422,10040753,48,3387,28,2921,0.106040881,1.478333608,0.906256787,2.453922931,0.220260347,DB0042210040753_,1.512945036,0.390915513,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,methylphenidate,DB00422
,45619,DB00422,10043071,25,3410,39,2910,0.022621377,0.547091718,0.316473579,0.929625991,0.068005133,DB0042210043071_,2.688172085,-0.603138815,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,methylphenidate,DB00422
,45621,DB00316,10048706,55,65419,24,36929,0.3485061,1.293658816,0.787304194,2.185653108,0.518039476,DB0031610048706_,0.657703832,0.257474495,NA,10048706,Joint range of motion decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,45626,DB00316,10049848,397,65077,192,36761,0.077893592,1.168042954,0.980209313,1.395661241,0.174807519,DB0031610049848_,1.744069799,0.155329659,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,45638,DB00316,10061296,46,65428,23,36930,0.707485804,1.128890904,0.670212207,1.951464342,0.825128976,DB0031610061296_,0.19221557,0.12123565,NA,10061296,Motor dysfunction,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,45644,DB00181,10007515,69,9787,73,5798,0.000639728,0.560003821,0.396334571,0.790454,0.003801344,DB0018110007515_,5.572400699,-0.579811672,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,baclofen,DB00181
,45649,DB00745,10040979,52,2525,42,1041,0.001842917,0.510521892,0.331098707,0.791197073,0.009094352,DB0074510040979_,4.700101742,-0.672321759,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,modafinil,DB00745
,45660,DB00182,10042209,62,5132,14,2838,0.00156491,2.448770205,1.352655062,4.745588751,0.007959302,DB0018210042209_,4.833414025,0.895585941,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,45663,DB00181,10000381,27,9829,32,5839,0.009830124,0.501248483,0.28862257,0.864602776,0.035085182,DB0018110000381_,3.349976405,-0.690653328,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,45664,DB00181,10021118,69,9787,90,5781,8.61542967202053e-07,0.452873818,0.325472024,0.627793797,1.25739349766274e-05,DB0018110021118_,11.28388454,-0.79214174,NA,10021118,Hypotonia,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,45669,DB00471,10019063,68,14121,20,5445,0.340178125,1.310984243,0.785692385,2.281686696,0.509346739,DB0047110019063_,0.674626277,0.270778185,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,montelukast,DB00471
,45670,DB09072,10019063,65,6406,30,2505,0.491290399,0.847288416,0.540272017,1.356425561,0.654464594,DB0907210019063_,0.423937791,-0.165714127,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,45671,DB00471,10040979,54,14135,24,5441,0.529762358,0.866116258,0.525711537,1.466558869,0.687006379,DB0047110040979_,0.375411701,-0.143736133,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,45672,DB00181,10035664,252,9604,175,5696,0.11602878,0.854058569,0.699423418,1.044730612,0.235216449,DB0018110035664_,1.447249128,-0.157755505,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,baclofen,DB00181
,45673,DB00422,10003239,57,3378,26,2923,0.007473302,1.896827944,1.16979751,3.151577437,0.028213393,DB0042210003239_,3.5679585,0.640182988,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,methylphenidate,DB00422
,45674,DB00422,10010264,99,3336,59,2890,0.023828128,1.453546304,1.038224613,2.050192619,0.070835743,DB0042210010264_,2.647391565,0.374006297,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,45675,DB00422,10010305,32,3403,39,2910,0.15136711,0.701688667,0.424351588,1.152696787,0.285783974,DB0042210010305_,1.252519091,-0.354265467,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,methylphenidate,DB00422
,45678,DB00422,10020751,40,3395,16,2933,0.009917723,2.159490027,1.179767088,4.139889039,0.035316312,DB0042210020751_,3.343410326,0.769872095,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,methylphenidate,DB00422
,45679,DB09072,10020751,79,6392,17,2518,0.022170628,1.830510019,1.071552016,3.305536338,0.067017992,DB0907210020751_,2.702794151,0.604594627,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,sodium oxybate,DB09072
,45680,DB00422,10033775,56,3379,15,2934,1.23015436306223e-05,3.240983037,1.803295071,6.184566873,0.000130198,DB0042210033775_,8.946456226,1.17587669,female,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,methylphenidate,DB00422
,45683,DB08890,10037844,51,1896,8,551,0.114297325,1.852194872,0.86569836,4.547589929,0.232576365,DB0889010037844_,1.458536656,0.616371353,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,linaclotide,DB08890
,45684,DB00181,10061224,42,9814,15,5856,0.09941781,1.670704428,0.90674875,3.246363133,0.209999726,DB0018110061224_,1.560649054,0.51324535,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,45685,DB00181,10058080,67,9789,56,5815,0.061636643,0.710757273,0.490159213,1.033952823,0.146451449,DB0018110058080_,1.921061309,-0.341424295,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,baclofen,DB00181
,45686,DB00181,10021097,144,9712,110,5761,0.049794417,0.776558691,0.6002738,1.006810517,0.124652024,DB0018110021097_,2.08222923,-0.252883055,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,baclofen,DB00181
,45687,DB00181,10043071,65,9791,76,5795,7.17636002051468e-05,0.506215622,0.357233261,0.715586256,0.000599456,DB0018110043071_,7.41948843,-0.680792569,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,baclofen,DB00181
,45691,DB09072,10013654,43,6428,51,2484,9.73760181457353e-08,0.325838347,0.211405067,0.500192387,1.76397562850493e-06,DB0907210013654_,13.24794042,-1.121353887,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,45697,DB00745,10016256,224,2353,83,1000,0.327421434,1.146907246,0.877496092,1.51027326,0.495852989,DB0074510016256_,0.70147579,0.137068968,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,modafinil,DB00745
,45698,DB01065,10016256,333,3998,186,2865,0.008405745,1.282916504,1.061939502,1.553479387,0.030983734,DB0106510016256_,3.474292934,0.249136004,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,45704,DB00181,10027175,177,9679,49,5822,4.84946213780117e-07,2.17269573,1.572455271,3.05098989,7.55265947427947e-06,DB0018110027175_,11.79361081,0.775968668,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,45715,DB09270,10005750,39,3075,26,2342,0.617312366,1.142386657,0.675849234,1.960604584,0.758368646,DB0927010005750_,0.276585672,0.133119633,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,ubidecarenone,DB09270
,45716,DB00482,10010264,224,8035,55,3016,0.004164957,1.5287343,1.129970228,2.098832639,0.017648863,DB0048210010264_,4.037083944,0.424440138,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,45717,DB01076,10010264,440,25307,287,25296,1.88794804596721e-08,1.532413193,1.316215531,1.786258991,3.9715657773708e-07,DB0107610010264_,14.73893523,0.426843743,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,45719,DB09270,10010264,54,3060,29,2339,0.146488766,1.423235788,0.887123211,2.325920334,0.279018639,DB0927010010264_,1.276476692,0.352933003,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,45721,DB01076,10013036,41,25706,24,25559,0.046287951,1.698536819,1.001918654,2.939743602,0.118061112,DB0107610013036_,2.136552894,0.529767186,NA,10013036,Diplopia,10015919,Eye disorders,Eye,atorvastatin,DB01076
,45727,DB01076,10015946,52,25695,21,25562,0.000369679,2.463478003,1.457832092,4.306912649,0.002401338,DB0107610015946_,6.031729248,0.901574174,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,atorvastatin,DB01076
,45730,DB00404,10015958,51,19841,7,9855,0.000380855,3.618539634,1.634414771,9.453454101,0.002462326,DB0040410015958_,6.006648809,1.286070528,female,10015958,Eye pain,10015919,Eye disorders,Eye,alprazolam,DB00404
,45735,DB00404,10022086,193,19699,31,9831,4.56843751681821e-11,3.106960048,2.116738313,4.702782087,1.58001815959956e-09,DB0040410022086_,20.2658295,1.133644772,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,45736,DB01076,10022086,213,25534,115,25468,8.54060033405087e-08,1.847353535,1.464667935,2.339955451,1.56930919105576e-06,DB0107610022086_,13.36487504,0.613754093,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,45739,DB00482,10022095,56,8203,9,3062,0.01652589,2.322517583,1.13828743,5.346987793,0.053142037,DB0048210022095_,2.934787004,0.842651762,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,45748,DB08890,10033371,88,1859,18,541,0.191561183,1.42253975,0.840826192,2.533975319,0.338579544,DB0889010033371_,1.082996223,0.35244383,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,linaclotide,DB08890
,45749,DB09270,10033371,161,2953,64,2304,3.66479525587359e-06,1.962496348,1.452258537,2.678675396,4.50241380232005e-05,DB0927010033371_,10.00831181,0.67421731,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,45750,DB00482,10037660,106,8153,52,3019,0.104709544,0.75484828,0.53521965,1.076138557,0.218055012,DB0048210037660_,1.523007898,-0.281238504,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,45751,DB09270,10037660,73,3041,57,2311,0.928656315,0.973260686,0.675801512,1.40753313,0.970364828,DB0927010037660_,0.030083167,-0.027103313,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,45754,DB01076,10037867,40,25707,35,25548,0.644348328,1.135785,0.703173541,1.842295156,0.780474911,DB0107610037867_,0.247852684,0.127324042,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,45757,DB00404,10037884,69,19823,24,9838,0.151433676,1.426823995,0.88461772,2.376182704,0.285889117,DB0040410037884_,1.252151248,0.355450992,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,45759,DB00588,10037884,73,16451,31,8437,0.407727399,1.207659041,0.782548172,1.904052118,0.57716642,DB0058810037884_,0.54962463,0.188683809,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,45768,DB00404,10042727,45,19847,7,9855,0.001755211,3.19199888,1.428221635,8.392456653,0.008732863,DB0040410042727_,4.740662036,1.160647329,female,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,45770,DB00588,10042727,38,16486,18,8450,0.887858597,1.082057446,0.602148753,2.015513352,0.953538943,DB0058810042727_,0.047575012,0.078864271,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,45773,DB00404,10046555,38,19854,31,9831,0.040806903,0.606972245,0.367507676,1.009530761,0.107256692,DB0040410046555_,2.232530329,-0.499272214,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,alprazolam,DB00404
,45775,DB01076,10046555,38,25709,58,25525,0.040989644,0.650492437,0.420228612,0.996522168,0.107649777,DB0107610046555_,2.228872123,-0.430025607,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,45781,DB01076,10047531,35,25712,26,25557,0.305540248,1.338026841,0.782457666,2.315463606,0.4723219,DB0107610047531_,0.750094534,0.291196022,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,atorvastatin,DB01076
,45790,DB00404,10047571,136,19756,33,9829,0.000105977,2.050340598,1.391855631,3.099990238,0.000838339,DB0040410047571_,7.084088199,0.718005925,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,alprazolam,DB00404
,45791,DB00482,10047571,52,8207,13,3058,0.211116162,1.490327795,0.798837435,2.988016313,0.362656492,DB0048210047571_,1.014299195,0.398996092,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,celecoxib,DB00482
,45792,DB00588,10047571,113,16411,34,8434,0.005096519,1.708006528,1.15384208,2.588050362,0.020770913,DB0058810047571_,3.874201688,0.535326917,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,fluticasone propionate,DB00588
,45793,DB01076,10047571,158,25589,86,25497,4.60627097160817e-06,1.830571775,1.398151017,2.410490642,5.50970796308172e-05,DB0107610047571_,9.806413844,0.604628363,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,atorvastatin,DB01076
,45795,DB09270,10047571,38,3076,17,2351,0.074985642,1.708278674,0.938398311,3.236236555,0.169806853,DB0927010047571_,1.773093647,0.53548624,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,ubidecarenone,DB09270
,45802,DB00060,10002855,190,9318,41,2424,0.323908058,1.205514282,0.853544443,1.738774483,0.492320656,DB0006010002855_,0.708625035,0.186906266,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,interferon beta-1a,DB00060
,45803,DB00268,10002855,70,2905,19,1526,0.009274789,1.935069086,1.146978805,3.416566817,0.033514962,DB0026810002855_,3.395763313,0.660143029,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ropinirole,DB00268
,45807,DB00996,10010947,58,38895,17,22408,0.011672079,1.96554762,1.128415794,3.601541182,0.040275759,DB0099610010947_,3.212005493,0.675770893,NA,10010947,Coordination abnormal,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,45812,DB01076,10011086,28,25719,50,25533,0.012497221,0.555959832,0.336906761,0.900634538,0.042528412,DB0107610011086_,3.157582911,-0.587059232,NA,10011086,Coronary artery occlusion,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,45813,DB00268,10013968,158,2817,57,1488,0.015000175,1.464076513,1.067481119,2.031986135,0.049318856,DB0026810013968_,3.009448802,0.381224677,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ropinirole,DB00268
,45814,DB00268,10016173,179,2796,82,1463,0.347265309,1.142200398,0.867570344,1.513856336,0.516691308,DB0026810016173_,0.660309666,0.132956576,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ropinirole,DB00268
,45815,DB00472,10016173,341,10418,110,4202,0.044454268,1.250315501,1.002494387,1.569364998,0.114511999,DB0047210016173_,2.167075667,0.22339592,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,45818,DB00451,10019909,60,47211,36,15383,0.005936479,0.543080609,0.353265643,0.845575394,0.023470006,DB0045110019909_,3.752031995,-0.610497519,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,45820,DB00996,10019909,42,38911,36,22389,0.098766445,0.671320663,0.419691809,1.078733843,0.208973357,DB0099610019909_,1.565548514,-0.398508368,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,45821,DB01076,10019909,32,25715,47,25536,0.091751509,0.676120357,0.417362095,1.082578523,0.198073308,DB0107610019909_,1.619118077,-0.391384177,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,45823,DB00472,10020772,152,10607,42,4270,0.030820215,1.456921187,1.027109697,2.106377879,0.08654319,DB0047210020772_,2.447111687,0.376325433,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,fluoxetine,DB00472
,45826,DB00451,10021688,86,47185,29,15390,0.913683794,0.967240485,0.62812201,1.529301293,0.961358547,DB0045110021688_,0.039407842,-0.033308122,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,levothyroxine,DB00451
,45828,DB00996,10021688,50,38903,13,22412,0.008472921,2.215738592,1.185495269,4.447370829,0.031183243,DB0099610021688_,3.467874402,0.795585798,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,gabapentin,DB00996
,45829,DB01076,10021688,33,25714,19,25564,0.070326765,1.726682023,0.953183531,3.215007627,0.161861478,DB0107610021688_,1.821014383,0.546201661,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,atorvastatin,DB01076
,45830,DB00268,10027175,61,2914,20,1525,0.076195737,1.596021355,0.945471478,2.803640017,0.171789247,DB0026810027175_,1.761486862,0.467513879,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ropinirole,DB00268
,45831,DB00451,10027175,559,46712,124,15295,5.63850140650488e-05,1.476040249,1.21193814,1.80950132,0.000489135,DB0045110027175_,7.622871328,0.389362995,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,45832,DB01076,10027175,292,25455,218,25365,0.001337824,1.334701703,1.115105026,1.599484936,0.006996734,DB0107610027175_,4.962311793,0.288707823,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,45834,DB00451,10028245,125,47146,10,15409,3.40504967278339e-07,4.085476579,2.148346215,8.732447753,5.47746209602885e-06,DB0045110028245_,12.11486869,1.407438387,female,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,45835,DB00472,10028245,54,10705,11,4301,0.038645197,1.972273925,1.018381361,4.187295731,0.102911606,DB0047210028245_,2.27388485,0.679187154,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,45836,DB00996,10028245,169,38784,46,22379,2.31416134855939e-06,2.119881386,1.521490413,3.005937263,3.00903937901971e-05,DB0099610028245_,10.41130458,0.751360137,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,45837,DB01076,10028245,61,25686,25,25558,0.000129592,2.427945096,1.50092938,4.038104251,0.000994986,DB0107610028245_,6.912782071,0.88704526,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,45838,DB00268,10028334,73,2902,28,1517,0.202622444,1.362776833,0.866150426,2.198943762,0.352104385,DB0026810028334_,1.043827598,0.309524407,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ropinirole,DB00268
,45839,DB00472,10028334,119,10640,30,4282,0.022439351,1.596347541,1.060187629,2.472809379,0.067600957,DB0047210028334_,2.694133136,0.467718233,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,fluoxetine,DB00472
,45840,DB00268,10028372,49,2926,23,1522,0.802350403,1.108145678,0.659480479,1.913437219,0.893104952,DB0026810028372_,0.113051177,0.102688058,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,ropinirole,DB00268
,45841,DB00472,10028372,83,10676,16,4296,0.005071153,2.087353825,1.210936776,3.824767784,0.020693202,DB0047210028372_,3.877950055,0.735897152,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,fluoxetine,DB00472
,45842,DB00996,10028372,402,38551,214,22211,0.377225461,1.082300546,0.913850975,1.284685752,0.547124941,DB0099610028372_,0.603078092,0.079088911,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,45843,DB01076,10028372,248,25499,258,25325,0.623207852,0.954667111,0.798029421,1.141935209,0.763308961,DB0107610028372_,0.2700924,-0.046392574,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,45844,DB00268,10033371,177,2798,33,1512,1.46958275331788e-09,2.897861269,1.977740907,4.363262212,3.94364294752021e-08,DB0026810033371_,17.04857584,1.063972972,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,45847,DB00472,10040984,43,10716,21,4291,0.488401634,0.819965552,0.475371871,1.456365054,0.651954546,DB0047210040984_,0.427780434,-0.198492949,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,45848,DB00996,10040984,139,38814,69,22356,0.348481603,1.16032754,0.862870141,1.57269114,0.518039476,DB0099610040984_,0.657703832,0.148702328,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,45849,DB01076,10040984,67,25680,83,25500,0.190994056,0.801575923,0.571823325,1.120024045,0.337804311,DB0107610040984_,1.085288512,-0.221175586,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,45850,DB00268,10041349,58,2917,49,1496,0.013001902,0.607104895,0.405669164,0.911892732,0.0438836,DB0026810041349_,3.126214611,-0.499053693,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ropinirole,DB00268
,45851,DB01076,10041349,258,25489,214,25369,0.052068599,1.19992567,0.996275585,1.446390815,0.128932937,DB0107610041349_,2.048462879,0.182259614,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,45853,DB00472,10042209,70,10689,9,4303,0.000393143,3.131164343,1.556575076,7.137302836,0.002526353,DB0047210042209_,5.98097833,1.14140493,female,10042209,Stress,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,45854,DB00996,10042209,163,38790,26,22399,3.48025076988989e-12,3.62005417,2.38235948,5.70955362,1.43158672122935e-10,DB0099610042209_,22.66706751,1.28648899,female,10042209,Stress,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,45855,DB00268,10044565,63,2912,25,1520,0.306859228,1.315327397,0.811814961,2.191613812,0.473929847,DB0026810044565_,0.746695971,0.274085606,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,ropinirole,DB00268
,45856,DB00472,10044565,162,10597,65,4247,1,0.998842343,0.742849923,1.356417345,1,DB0047210044565_,0,-0.001158328,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,45857,DB00996,10044565,524,38429,280,22145,0.319734771,1.07843203,0.930083049,1.252515041,0.487866278,DB0099610044565_,0.71771393,0.075508162,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,45858,DB01076,10044565,246,25501,229,25354,0.489442165,1.068072641,0.887702934,1.285454305,0.652796514,DB0107610044565_,0.426489815,0.065855754,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,45859,DB00060,10047571,127,9381,32,2433,1,1.029316664,0.69185987,1.572250341,1,DB0006010047571_,0,0.028895149,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,interferon beta-1a,DB00060
,45861,DB00451,10047571,382,46889,73,15346,1.14203927221842e-05,1.712549888,1.32926549,2.232758821,0.000121853,DB0045110047571_,9.012694634,0.537983422,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,levothyroxine,DB00451
,45862,DB00472,10047571,53,10706,18,4294,0.600327418,1.180947906,0.679759542,2.14491867,0.74476261,DB0047210047571_,0.294689756,0.166317426,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,fluoxetine,DB00472
,45863,DB00268,10049848,45,2930,25,1520,0.800118917,0.933803738,0.558031663,1.595610386,0.891935108,DB0026810049848_,0.114361898,-0.068488993,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,ropinirole,DB00268
,45864,DB00451,10049848,395,46876,106,15313,0.076516555,1.217299964,0.97921161,1.524247919,0.172357327,DB0045110049848_,1.758185477,0.196635262,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,45865,DB00472,10049848,75,10684,21,4291,0.17344834,1.434293825,0.873081335,2.454023301,0.315475183,DB0047210049848_,1.153675259,0.36067262,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,45866,DB01076,10049848,189,25558,188,25395,1,0.998907586,0.811311771,1.229914126,1,DB0107610049848_,0,-0.001093011,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,45867,DB00451,10050584,470,46801,109,15310,0.000967211,1.410526764,1.141953264,1.755191888,0.005359575,DB0045110050584_,5.228870512,0.343963226,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,45868,DB00472,10050584,83,10676,17,4295,0.010229326,1.964116426,1.154234093,3.535808431,0.036210142,DB0047210050584_,3.318416023,0.675042488,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,45869,DB00060,10061024,50,9458,15,2450,0.644135329,0.86345176,0.47611465,1.658604921,0.780360755,DB0006010061024_,0.24799896,-0.146817249,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,interferon beta-1a,DB00060
,45871,DB00472,10061024,36,10723,18,4294,0.451971179,0.8008812,0.442473068,1.499893016,0.619527661,DB0047210061024_,0.478797928,-0.222042657,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,fluoxetine,DB00472
,45872,DB00996,10061024,165,38788,124,22301,0.027357424,0.765069901,0.602029184,0.974279233,0.078774737,DB0099610061024_,2.541162926,-0.267788075,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,gabapentin,DB00996
,45873,DB01076,10061024,173,25574,231,25352,0.003180499,0.74242369,0.605570574,0.908793246,0.014192244,DB0107610061024_,4.255059691,-0.297835188,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,45874,DB00181,10028372,239,9617,127,5744,0.299429716,1.124020918,0.900231739,1.408744295,0.465445085,DB0018110028372_,0.764761159,0.116912362,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,45875,DB00813,10028372,75,10497,36,10132,0.000550156,2.010817322,1.332879151,3.084058518,0.003338916,DB0081310028372_,5.702109037,0.698541267,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,fentanyl,DB00813
,45876,DB00813,10033775,85,10487,42,10126,0.000335133,1.954072172,1.333473856,2.90262352,0.002212198,DB0081310033775_,6.113768735,0.669915488,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,45879,DB01069,10002855,194,6506,30,2365,3.28401969471141e-06,2.350526102,1.589130618,3.58834331,4.09781427369995e-05,DB0106910002855_,10.10247174,0.854639176,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,promethazine,DB01069
,45880,DB08890,10002855,61,1886,9,550,0.058011479,1.976013586,0.967504461,4.556163274,0.13970697,DB0889010002855_,1.968208123,0.681081475,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,linaclotide,DB08890
,45881,DB01069,10003239,185,6515,39,2356,0.001611893,1.715368821,1.204608665,2.497611696,0.008147027,DB0106910003239_,4.810102195,0.539628113,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,promethazine,DB01069
,45882,DB08890,10003239,45,1902,6,553,0.087285288,2.179950101,0.920562501,6.286322825,0.190579705,DB0889010003239_,1.65768477,0.779301987,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,linaclotide,DB08890
,45884,DB00231,10003988,90,3206,27,2112,0.000244861,2.195587762,1.408828491,3.524824318,0.001704723,DB0023110003988_,6.374352815,0.786449784,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,temazepam,DB00231
,45891,DB00231,10005750,38,3258,12,2127,0.028535702,2.067117063,1.054497086,4.355437638,0.081466377,DB0023110005750_,2.507564896,0.726154913,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,temazepam,DB00231
,45892,DB01069,10005750,80,6620,24,2371,0.502555133,1.193828346,0.746421419,1.975432724,0.663735387,DB0106910005750_,0.409871722,0.177165241,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,promethazine,DB01069
,45894,DB00231,10008479,43,3253,37,2102,0.206684857,0.751011407,0.470847639,1.203063778,0.357297696,DB0023110008479_,1.029185962,-0.286334438,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,45895,DB01069,10008479,131,6569,43,2352,0.664629151,1.090778251,0.764784162,1.582709116,0.795853366,DB0106910008479_,0.228340324,0.086891434,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,45898,DB01069,10010305,61,6639,48,2347,6.5234437478402e-05,0.44930051,0.301827247,0.672186681,0.000552501,DB0106910010305_,7.501055119,-0.800063327,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,promethazine,DB01069
,45901,DB00231,10016256,265,3031,135,2004,0.016783537,1.297786638,1.042520842,1.621342813,0.053838818,DB0023110016256_,2.921760539,0.260660227,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,45902,DB00231,10019211,168,3128,49,2090,1.1749261784739e-07,2.29049969,1.648428375,3.232650876,2.10231004773222e-06,DB0023110019211_,13.0724738,0.828769999,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,temazepam,DB00231
,45903,DB01069,10019211,443,6257,74,2321,1.64155321999063e-11,2.22049289,1.723921446,2.893546578,6.03049984450786e-10,DB0106910019211_,21.22902103,0.797729194,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,45904,DB00231,10020937,50,3246,15,2124,0.006965515,2.180858024,1.201254696,4.193250265,0.026686755,DB0023110020937_,3.623587913,0.779718388,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,temazepam,DB00231
,45905,DB01069,10020937,119,6581,26,2369,0.022121967,1.647568159,1.067532976,2.631877073,0.066913221,DB0106910020937_,2.704358708,0.499300358,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,45907,DB09072,10020937,69,6402,18,2517,0.149797732,1.507101695,0.884745987,2.69660587,0.283656321,DB0907210020937_,1.25999191,0.410188399,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,45914,DB00231,10027175,47,3249,9,2130,0.00026832,3.422969627,1.654001339,7.961473538,0.001842183,DB0023110027175_,6.296803756,1.230508486,female,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,temazepam,DB00231
,45917,DB01069,10028372,54,6646,20,2375,0.894801391,0.964868045,0.566782845,1.705545547,0.955976233,DB0106910028372_,0.045022227,-0.035763928,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,promethazine,DB01069
,45921,DB00231,10030095,32,3264,18,2121,0.665341501,1.155237537,0.627320702,2.191807753,0.796379843,DB0023110030095_,0.227679017,0.144305982,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,45922,DB01069,10030095,55,6645,7,2388,0.005547268,2.823551965,1.279923571,7.359599765,0.022230047,DB0106910030095_,3.806310434,1.037995655,female,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,45926,DB00231,10033425,61,3235,34,2105,0.525553311,1.167354106,0.752281154,1.838658966,0.683569636,DB0023110033425_,0.380426747,0.15473974,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,temazepam,DB00231
,45927,DB08890,10033425,52,1895,10,549,0.280806022,1.506241365,0.750916377,3.346739298,0.44467791,DB0889010033425_,0.810405056,0.409617386,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,linaclotide,DB08890
,45929,DB01069,10043071,54,6646,23,2372,0.515744818,0.837999241,0.504360974,1.433966874,0.67545354,DB0106910043071_,0.392370903,-0.176738084,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,promethazine,DB01069
,45931,DB09072,10043071,70,6401,25,2510,0.732285024,1.09794086,0.684727899,1.814056475,0.84442659,DB0907210043071_,0.169097474,0.09343648,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,sodium oxybate,DB09072
,45933,DB00231,10044565,57,3239,28,2111,0.2631199,1.326698,0.826873404,2.173920635,0.424923704,DB0023110044565_,0.855845647,0.282693148,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,temazepam,DB00231
,45934,DB01069,10044565,62,6638,20,2375,0.801222549,1.10913064,0.659145442,1.943190119,0.892454221,DB0106910044565_,0.11378006,0.103576501,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,45935,DB01069,10047895,162,6538,81,2314,0.014660307,0.707890769,0.536487399,0.94017446,0.048419445,DB0106910047895_,3.02785378,-0.345465478,NA,10047895,Weight decreased,10022891,Investigations,Inv,promethazine,DB01069
,45937,DB00231,10061428,67,3229,39,2100,0.616856305,1.117281659,0.738832169,1.710079028,0.758003225,DB0023110061428_,0.277067639,0.110898645,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,temazepam,DB00231
,45938,DB01069,10061428,134,6566,63,2332,0.072146966,0.755450801,0.553709309,1.040027646,0.165032025,DB0106910061428_,1.80161573,-0.28044062,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,promethazine,DB01069
,45942,DB01069,10074903,46,6654,11,2384,0.290440828,1.498151767,0.762854534,3.212868241,0.455666537,DB0106910074903_,0.785994016,0.404232193,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,promethazine,DB01069
,45944,DB00331,10005750,198,24748,133,20619,0.059510374,1.240333943,0.989827373,1.558298619,0.142579299,DB0033110005750_,1.94785695,0.215380652,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,metformin,DB00331
,45945,DB01238,10005750,36,5214,15,3487,0.151209144,1.604979534,0.855525396,3.160321146,0.285547263,DB0123810005750_,1.253347718,0.473111005,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,aripiprazole,DB01238
,45946,DB00331,10016334,71,24875,22,20730,2.27907715497802e-05,2.689362733,1.646397958,4.559340641,0.000223403,DB0033110016334_,8.406532766,0.989304263,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,45947,DB00999,10016334,76,21354,32,12207,0.1609935,1.357655285,0.886706979,2.122496866,0.298818214,DB0099910016334_,1.20791987,0.305759157,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,45949,DB09072,10016334,43,6428,14,2521,0.657926911,1.204551239,0.645021341,2.388300623,0.790952721,DB0907210016334_,0.234517084,0.186107082,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,45950,DB01238,10020642,49,5201,31,3471,0.90883687,1.05487826,0.657846446,1.715023764,0.95913476,DB0123810020642_,0.041723693,0.053425367,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,aripiprazole,DB01238
,45951,DB01238,10033775,49,5201,25,3477,0.286192321,1.310269726,0.792025552,2.218342491,0.450912016,DB0123810033775_,0.796483046,0.270233014,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,45952,DB00331,10049414,88,24858,73,20679,1,1.00282038,0.726520721,1.38778678,1,DB0033110049414_,0,0.00281641,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,45953,DB00999,10049414,50,21380,42,12197,0.065699401,0.679186618,0.441270382,1.04983761,0.153637195,DB0099910049414_,1.873161335,-0.386859346,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,45954,DB01238,10049414,94,5156,88,3414,0.021800154,0.707331555,0.521441978,0.960220286,0.066168249,DB0123810049414_,2.715554553,-0.346255762,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,45955,DB09072,10049414,33,6438,22,2513,0.069545237,0.585546429,0.330541529,1.056451046,0.160491356,DB0907210049414_,1.829515192,-0.535209802,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,45956,DB01593,10016173,49,1084,9,689,0.000176041,3.458625298,1.667564455,8.060929063,0.001295237,DB0159310016173_,6.64906156,1.240871197,female,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,zinc,DB01593
,45958,DB14513,10044565,94,7083,37,3527,0.262524237,1.264996836,0.854194254,1.908391957,0.424303607,DB1451310044565_,0.857306025,0.235069621,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,45959,DB01156,10047700,438,13184,105,6223,6.25355899881763e-11,1.968903296,1.584110622,2.46542188,2.11142965040362e-09,DB0115610047700_,19.97590056,0.677476685,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,45960,DB14513,10047700,259,6918,59,3505,4.81456022453735e-09,2.223960977,1.66509175,3.012169797,1.15995156280444e-07,DB1451310047700_,15.9697174,0.79928983,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,45961,DB09072,10033295,46,6425,33,2502,0.01132212,0.542889077,0.338793992,0.87857014,0.039292569,DB0907210033295_,3.23671987,-0.610850258,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium oxybate,DB09072
,45962,DB09072,10051076,57,6414,24,2511,0.804041145,0.929784967,0.566387045,1.570233505,0.89404042,DB0907210051076_,0.112004292,-0.072801938,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium oxybate,DB09072
,45963,DB00181,10038435,41,9815,32,5839,0.275234575,0.762252618,0.467817671,1.251989015,0.438529311,DB0018110038435_,0.824328625,-0.271477259,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,baclofen,DB00181
,45969,DB00181,10005750,89,9767,50,5821,0.791867258,1.060857881,0.740789287,1.534005708,0.887301788,DB0018110005750_,0.11957012,0.059077902,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,baclofen,DB00181
,45970,DB00295,10005750,68,14595,39,9563,0.552877172,1.142470471,0.758929439,1.741323683,0.706569902,DB0029510005750_,0.347333141,0.133192997,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,morphine,DB00295
,45971,DB00295,10012373,45,14618,46,9556,0.040679809,0.639534827,0.414092009,0.987112851,0.107000221,DB0029510012373_,2.234924379,-0.447014199,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,morphine,DB00295
,45975,DB08890,10013709,179,1768,55,504,0.621835242,0.927787386,0.67040757,1.300144362,0.762090655,DB0889010013709_,0.27168976,-0.074952683,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,linaclotide,DB08890
,45976,DB01238,10013709,355,4895,274,3228,0.063053314,0.854414571,0.723107939,1.010338121,0.149049539,DB0123810013709_,1.90347655,-0.157338757,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,45978,DB01238,10019070,39,5211,58,3444,9.58130283278341e-05,0.444442671,0.28767266,0.680177369,0.000768263,DB0123810019070_,7.171377897,-0.810934205,NA,10019070,"Hallucination, auditory",10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,45979,DB01238,10033295,74,5176,47,3455,0.851938241,1.0509637,0.717452174,1.552785211,0.927294854,DB0123810033295_,0.075483691,0.049707553,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole,DB01238
,45981,DB09072,10000125,67,6404,26,2509,1,1.009604426,0.631522719,1.658843797,1,DB0907210000125_,0,0.009558596,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,45983,DB06413,10005750,48,1508,16,658,0.408718123,1.308821401,0.723940605,2.488136999,0.578101858,DB0641310005750_,0.548005202,0.269127038,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,armodafinil,DB06413
,45988,DB06413,10016256,127,1429,47,627,0.389917737,1.185500568,0.830055996,1.716869724,0.559855119,DB0641310016256_,0.580077245,0.170165106,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,armodafinil,DB06413
,45990,DB09072,10017885,88,6383,17,2518,0.006024688,2.04190584,1.202659858,3.669820996,0.023741966,DB0907210017885_,3.740511086,0.713883607,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,sodium oxybate,DB09072
,45991,DB06413,10019211,109,1447,28,646,0.00942504,1.737543687,1.124916127,2.763495213,0.033945899,DB0641310019211_,3.382987238,0.552472441,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,armodafinil,DB06413
,45994,DB09072,10022998,87,6384,44,2491,0.170853642,0.771530583,0.529238445,1.138908387,0.31196471,DB0907210022998_,1.164865205,-0.259378967,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,45996,DB09072,10041235,68,6403,24,2511,0.727364788,1.111105077,0.686759713,1.855153651,0.840718677,DB0907210041235_,0.173498185,0.105355085,NA,10041235,Snoring,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium oxybate,DB09072
,45997,DB06413,10044565,46,1510,9,665,0.024996264,2.250237336,1.080207706,5.260761517,0.073460061,DB0641310044565_,2.611013404,0.811035693,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,armodafinil,DB06413
,46001,DB00327,10020642,45,6093,61,4201,0.000670752,0.508657549,0.337475265,0.761702291,0.003954846,DB0032710020642_,5.532813533,-0.67598028,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,hydromorphone,DB00327
,46002,DB00297,10033295,63,1609,33,846,1,1.00378406,0.642814439,1.592887358,1,DB0029710033295_,0,0.003776918,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,bupivacaine,DB00297
,46003,DB00297,10047700,41,1631,20,859,0.891695376,1.079649988,0.613700017,1.958175247,0.955005127,DB0029710047700_,0.04603857,0.076636904,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,bupivacaine,DB00297
,46006,DB08890,10013573,78,1869,30,529,0.192823829,0.735998767,0.471497688,1.175214732,0.3401936,DB0889010013573_,1.078240413,-0.306526835,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,linaclotide,DB08890
,46010,DB00126,10000060,96,10075,44,5901,0.187882301,1.27789925,0.884113026,1.872650695,0.333940987,DB0012610000060_,1.096790987,0.245217519,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,46011,DB01592,10002034,201,6075,92,2975,0.613749978,1.06991108,0.828467185,1.390195487,0.755369411,DB0159210002034_,0.280548363,0.067575543,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,iron,DB01592
,46012,DB01592,10003988,152,6124,57,3010,0.0868835,1.310689454,0.95738538,1.815700545,0.189852257,DB0159210003988_,1.661509105,0.270553299,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,iron,DB01592
,46013,DB01592,10013573,250,6026,96,2971,0.041176074,1.283938042,1.006320506,1.648919084,0.108053022,DB0159210013573_,2.225133227,0.24993195,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,iron,DB01592
,46015,DB00999,10024378,53,21377,37,12202,0.380181467,0.817648752,0.526933166,1.280741608,0.55033658,DB0099910024378_,0.597225224,-0.201322433,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,hydrochlorothiazide,DB00999
,46018,DB00316,10028810,877,64597,368,36585,1.08535834472894e-06,1.349712367,1.192812202,1.529635109,1.5375178707195e-05,DB0031610028810_,11.08275612,0.299891508,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,46019,DB01592,10028810,132,6144,48,3019,0.078132904,1.351257263,0.961211249,1.927320817,0.175242087,DB0159210028810_,1.741586905,0.301035465,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,iron,DB01592
,46024,DB00316,10038435,426,65048,332,36621,1.22023187301791e-05,0.72241035,0.623981913,0.836868776,0.000129252,DB0031610038435_,8.953749346,-0.32516195,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,46025,DB01373,10038435,116,22604,63,7318,0.001602795,0.596119679,0.434441227,0.824517838,0.008108102,DB0137310038435_,4.814891492,-0.517313828,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,calcium,DB01373
,46026,DB01592,10038435,63,6213,39,3028,0.244812443,0.787326689,0.518567405,1.20867938,0.403568207,DB0159210038435_,0.907409766,-0.23911201,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,iron,DB01592
,46029,DB00316,10043255,43,65431,10,36943,0.009394061,2.427801108,1.201135938,5.419384583,0.033859843,DB0031610043255_,3.385525539,0.886985954,NA,10043255,Tendonitis,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,46040,DB00316,10049816,88,65386,28,36925,0.006685933,1.774834389,1.148232514,2.821910316,0.025826991,DB0031610049816_,3.656335177,0.573707116,NA,10049816,Muscle tightness,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,46041,DB00695,10049816,39,28010,21,20507,0.296037019,1.35966303,0.780151213,2.433560589,0.461894035,DB0069510049816_,0.772419776,0.307236897,NA,10049816,Muscle tightness,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,46045,DB00181,10000081,102,9754,52,5819,0.402603216,1.170229491,0.828564623,1.669983989,0.572378805,DB0018110000081_,0.55795426,0.157199875,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,baclofen,DB00181
,46051,DB00295,10003553,43,14620,12,9590,0.008105664,2.350405958,1.216841864,4.898563541,0.030110771,DB0029510003553_,3.502872345,0.854588061,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,46055,DB09153,10003553,45,7754,15,5684,0.008238589,2.198985739,1.201674149,4.251515713,0.030495889,DB0915310003553_,3.490163399,0.787996226,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,46057,DB00813,10010774,207,10365,142,10026,0.001715497,1.410040348,1.131295823,1.761462301,0.008572029,DB0081310010774_,4.759250781,0.34361832,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,46058,DB09153,10010774,101,7698,62,5637,0.299980008,1.192865308,0.859257564,1.667310737,0.466042586,DB0915310010774_,0.763478262,0.176358235,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,46061,DB00327,10016173,163,5975,94,4168,0.157720735,1.209592085,0.929656139,1.581254753,0.294417266,DB0032710016173_,1.222757246,0.190283183,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,hydromorphone,DB00327
,46062,DB09153,10016173,164,7635,105,5594,0.289992052,1.144334228,0.887980608,1.479978142,0.455220586,DB0915310016173_,0.786973174,0.134823007,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium chloride,DB09153
,46069,DB00181,10017944,50,9806,17,5854,0.043263352,1.755768466,0.99434271,3.250612694,0.112186377,DB0018110017944_,2.187593708,0.562906633,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,baclofen,DB00181
,46070,DB00295,10017944,54,14609,23,9579,0.101575953,1.539422877,0.928213544,2.630088817,0.213277849,DB0029510017944_,1.54515951,0.431407591,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,46073,DB00813,10017944,32,10540,22,10146,0.275480232,1.400145016,0.788068551,2.531126003,0.438781875,DB0081310017944_,0.823752858,0.336575814,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,46074,DB09153,10017944,30,7769,20,5679,0.776447907,1.096490181,0.601718727,2.039329048,0.878124615,DB0915310017944_,0.129966765,0.092114334,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,46075,DB00297,10020937,71,1601,52,827,0.064971224,0.705365527,0.481213011,1.039706278,0.152397699,DB0029710020937_,1.881261736,-0.349039132,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,bupivacaine,DB00297
,46076,DB09153,10020937,51,7748,28,5671,0.253568563,1.333131008,0.823750315,2.198630704,0.414055394,DB0915310020937_,0.881755513,0.287530317,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,46083,DB00327,10028334,86,6052,59,4203,1,1.012293832,0.716606091,1.438374275,1,DB0032710028334_,0,0.012218877,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,hydromorphone,DB00327
,46095,DB00181,10039203,44,9812,26,5845,1,1.008105845,0.606423131,1.707485497,1,DB0018110039203_,0,0.008073169,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,46096,DB00295,10039203,38,14625,32,9570,0.327683518,0.777069964,0.472359676,1.285797925,0.496164133,DB0029510039203_,0.700848493,-0.252224889,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,46107,DB00181,10040979,31,9825,30,5841,0.063116717,0.614367187,0.359308591,1.051713036,0.149179292,DB0018110040979_,1.902606393,-0.487162504,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,baclofen,DB00181
,46151,DB00813,10060933,35,10537,36,10132,0.812697112,0.934887004,0.56950717,1.533122962,0.899275924,DB0081310060933_,0.106165369,-0.067329608,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,46192,DB06724,10012174,124,7805,69,3850,0.440753683,0.88647694,0.653394647,1.211018854,0.609074736,DB0672410012174_,0.495814299,-0.120500166,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,calcium carbonate,DB06724
,46195,DB06724,10027635,49,7880,50,3869,0.000353441,0.48119059,0.317169374,0.72978483,0.002311568,DB0672410027635_,6.069829345,-0.731491851,NA,10027635,Milk-alkali syndrome,10027433,Metabolism and nutrition disorders,Metab,calcium carbonate,DB06724
,46204,DB00404,10010774,390,19502,152,9710,0.011256093,1.277536424,1.054759728,1.553650872,0.039126321,DB0040410010774_,3.24095988,0.244933554,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,46205,DB01373,10010774,546,22174,190,7191,0.409966766,0.93192772,0.786907342,1.107478201,0.579402268,DB0137310010774_,0.545758279,-0.070500021,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,46208,DB00451,10011781,209,47062,24,15395,4.34215485441885e-08,2.848768806,1.861864228,4.548221426,8.49840211082646e-07,DB0045110011781_,13.97821749,1.046886903,female,10011781,Cystitis,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,46209,DB01076,10011781,110,25637,30,25553,6.06490688665211e-12,3.654257373,2.420804247,5.67255386,2.40628041533058e-10,DB0107610011781_,22.14776877,1.295892891,female,10011781,Cystitis,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,46210,DB06643,10011781,224,52197,13,7502,0.000517713,2.476464083,1.418001857,4.726409337,0.003176859,DB0664310011781_,5.751862356,0.90683177,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,denosumab,DB06643
,46211,DB00327,10019211,236,5902,92,4170,8.35579089032369e-07,1.812323446,1.413601701,2.339720258,1.22255476511082e-05,DB0032710019211_,11.31198273,0.594609694,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,46212,DB01076,10025482,744,25003,432,25151,6.4952472434639e-20,1.73238625,1.534626684,1.957612832,6.61734782149025e-18,DB0107610025482_,39.55683702,0.549499793,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,46223,DB00338,10033647,60,33614,40,22232,1,0.992085556,0.653797376,1.519864731,1,DB0033810033647_,0,-0.00794593,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,46224,DB00451,10033647,42,47229,28,15391,0.004955652,0.488809004,0.295855553,0.819191961,0.020326021,DB0045110033647_,3.895853409,-0.71578345,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,46225,DB01076,10033647,50,25697,57,25526,0.499180819,0.871358707,0.583628637,1.297309414,0.661039238,DB0107610033647_,0.41394208,-0.137701553,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,46228,DB01373,10047700,512,22208,111,7270,6.08053170201053e-05,1.509918116,1.225353266,1.874332712,0.000521713,DB0137310047700_,7.558392941,0.412055421,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,46229,DB01042,10002034,22,968,34,1294,0.682230736,0.865040836,0.478676259,1.533565032,0.80782192,DB0104210002034_,0.21341364,-0.144978564,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,melphalan,DB01042
,46230,DB01042,10028116,31,959,52,1276,0.366203973,0.793292473,0.487382509,1.272197857,0.535816273,DB0104210028116_,0.623963952,-0.231563307,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,melphalan,DB01042
,46235,DB00316,10000804,245,65229,109,36844,0.040149906,1.269621545,1.008690889,1.606611914,0.10597914,DB0031610000804_,2.244512999,0.23871886,NA,10000804,Acute hepatic failure,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,46236,DB00412,10048561,19,1045,37,1349,0.172767637,0.663007689,0.357935714,1.190799936,0.314476461,DB0041210048561_,1.156846051,-0.410968692,NA,10048561,Stent placement,10042613,Surgical and medical procedures,Surg,rosiglitazone,DB00412
,46237,DB00404,10003246,99,19793,29,9833,0.010938684,1.69591684,1.110487854,2.663619775,0.038247198,DB0040410003246_,3.263684966,0.528223503,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,46238,DB00641,10003246,80,14044,40,12435,0.003198858,1.770820053,1.196030908,2.659315739,0.014256014,DB0064110003246_,4.25057641,0.571442746,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,46239,DB00722,10003246,152,25251,89,25943,2.42569340918685e-05,1.754637718,1.341143402,2.307121209,0.000235361,DB0072210003246_,8.354389168,0.562262407,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,46240,DB00641,10022052,37,14087,16,12459,0.018381041,2.045144431,1.109434643,3.939836802,0.057802915,DB0064110022052_,2.85071608,0.715468413,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,46241,DB00404,10061623,81,19811,56,9806,0.05641174,0.715934332,0.502581182,1.026194204,0.136832241,DB0040410061623_,1.98899962,-0.334166832,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,46242,DB00641,10061623,78,14046,70,12405,0.934345011,0.984101263,0.70281391,1.380205407,0.97479745,DB0064110061623_,0.025525574,-0.016026478,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,46243,DB00722,10061623,159,25244,146,25886,0.358194192,1.116734435,0.885741899,1.408754672,0.527902121,DB0072210061623_,0.638844389,0.110408743,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,46248,DB06186,10038695,30,2179,44,3602,0.630430001,1.127053903,0.681936409,1.839859045,0.769328241,DB0618610038695_,0.26223756,0.119607063,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipilimumab,DB06186
,46259,DB06186,10037844,94,2115,145,3501,0.633495778,1.073089577,0.814077903,1.409037038,0.772036715,DB0618610037844_,0.258723172,0.070541943,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ipilimumab,DB06186
,46267,DB00635,10036807,40,33013,45,23749,0.047049692,0.639470624,0.406864177,1.001762753,0.119544659,DB0063510036807_,2.124065258,-0.447114594,NA,10036807,Progressive multifocal leukoencephalopathy,10021881,Infections and infestations,Infec,prednisone,DB00635
,46273,DB00635,10065042,12,33041,53,23741,7.09688301098582e-11,0.162721409,0.079113483,0.308421171,2.37632573176767e-09,DB0063510065042_,19.85771035,-1.815715687,male,10065042,Immune reconstitution inflammatory syndrome,10021428,Immune system disorders,Immun,prednisone,DB00635
,46278,DB00451,10005364,81,47190,43,15376,0.011922606,0.613781751,0.418781528,0.910765048,0.040949412,DB0045110005364_,3.195417835,-0.488115869,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,levothyroxine,DB00451
,46280,DB00588,10005364,32,16492,19,8449,0.65729618,0.862848999,0.474098804,1.612262033,0.790542601,DB0058810005364_,0.235035733,-0.147515575,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,46283,DB00193,10022523,81,19239,28,8674,0.254267746,1.304205145,0.838646798,2.083970901,0.414874931,DB0019310022523_,0.879778176,0.265593771,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,46284,DB00451,10022523,41,47230,29,15390,0.001992911,0.460685246,0.279339051,0.768936395,0.009695653,DB0045110022523_,4.636077608,-0.775040232,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,46285,DB01068,10022523,123,13640,64,6776,0.75560519,0.954740468,0.699153513,1.314463359,0.862925027,DB0106810022523_,0.147427467,-0.046315737,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,46291,DB00193,10060795,56,19264,24,8678,0.904068377,1.051112141,0.640381327,1.774594801,0.957450283,DB0019310060795_,0.043481484,0.049848786,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,tramadol,DB00193
,46301,DB00563,10000060,136,46510,47,15301,0.796925947,0.951947797,0.678256996,1.356928334,0.890074285,DB0056310000060_,0.116450354,-0.049245081,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,46302,DB00563,10013781,181,46465,17,15331,7.30306474646171e-09,3.513027448,2.133157097,6.164458838,1.689798035746e-07,DB0056310013781_,15.59348663,1.256478187,female,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,46303,DB00005,10016275,127,127955,26,42393,0.024419534,1.618271855,1.054759727,2.572473631,0.072225435,DB0000510016275_,2.627963014,0.481358823,NA,10016275,Fear,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,46306,DB00563,10024774,99,46547,31,15317,0.918974823,1.050854847,0.695473151,1.628816459,0.964243073,DB0056310024774_,0.036411866,0.049603973,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,46308,DB00563,10037162,374,46272,153,15195,0.025616939,0.802712048,0.662706619,0.976190296,0.074873928,DB0056310037162_,2.591949534,-0.219759225,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,46309,DB00005,10039674,167,127915,35,42384,0.011550219,1.580936306,1.092702541,2.346595303,0.039960185,DB0000510039674_,3.21987169,0.45801727,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,46310,DB00563,10039674,58,46588,10,15338,0.066321684,1.909396372,0.967348767,4.191644809,0.154757465,DB0056310039674_,1.865896132,0.646787156,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,46316,DB00563,10049187,104,46542,18,15330,0.008585355,1.902966988,1.146389815,3.337586463,0.031513204,DB0056310049187_,3.457348636,0.643414241,NA,10049187,Red blood cell sedimentation rate increased,10022891,Investigations,Inv,methotrexate,DB00563
,46319,DB00563,10060820,67,46579,15,15333,0.200870675,1.470309237,0.830802898,2.772602596,0.350020597,DB0056310060820_,1.049763277,0.385472744,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,46322,DB00996,10008190,289,38664,191,22234,0.140306546,0.870118986,0.721693534,1.050967777,0.270279044,DB0099610008190_,1.308300356,-0.139125312,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,46326,DB00213,10042772,150,18745,122,13299,0.266664645,0.872304204,0.681564985,1.118215326,0.428859533,DB0021310042772_,0.846625843,-0.136617058,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,46333,DB00264,10051055,202,29405,199,24693,0.118773002,0.85241905,0.696859988,1.042798814,0.239392556,DB0026410051055_,1.429650581,-0.159677031,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,46334,DB00482,10051055,33,8226,28,3043,0.002059701,0.436014598,0.255006201,0.750357176,0.009962136,DB0048210051055_,4.608963723,-0.830079554,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,celecoxib,DB00482
,46356,DB00709,10036590,32,608,26,613,0.501949279,1.240679005,0.706890939,2.195788519,0.663333341,DB0070910036590_,0.410477638,0.215658814,NA,10036590,Premature baby,10036585,"Pregnancy, puerperium and perinatal conditions",Preg,lamivudine,DB00709
,46364,DB00709,10071404,109,531,115,524,0.659572825,0.935403774,0.693370438,1.261298125,0.792035804,DB0070910071404_,0.233148681,-0.066776999,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,lamivudine,DB00709
,46366,DB00273,10003239,179,8302,29,2164,0.015256877,1.608813952,1.078896286,2.478626407,0.049972215,DB0027310003239_,2.996288129,0.475497232,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,topiramate,DB00273
,46369,DB00364,10003239,76,2674,25,1375,0.055360066,1.56304552,0.978014388,2.57646354,0.134949667,DB0036410003239_,2.002853404,0.446636174,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sucralfate,DB00364
,46370,DB00381,10003239,779,28581,371,22516,6.13857370272969e-16,1.654140375,1.458026853,1.879187611,4.19642158065669e-14,DB0038110003239_,30.80195914,0.503281463,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,46371,DB00395,10003239,64,2120,17,719,0.436941271,1.276688134,0.732902463,2.341342498,0.605509493,DB0039510003239_,0.501685039,0.24426933,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,carisoprodol,DB00395
,46372,DB00402,10003239,45,1307,20,676,0.68993782,1.163632536,0.666888097,2.098120473,0.812974205,DB0040210003239_,0.207055898,0.151546609,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,eszopiclone,DB00402
,46373,DB00410,10003239,65,1540,24,985,0.026176044,1.731936881,1.061266965,2.913406421,0.076139803,DB0041010003239_,2.575184116,0.549240367,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,mupirocin,DB00410
,46377,DB00557,10003239,173,5814,47,3020,4.89846270862731e-05,1.911843336,1.373249405,2.707094734,0.000434288,DB0055710003239_,7.741802918,0.648067874,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxyzine,DB00557
,46378,DB00590,10003239,19,757,32,1920,0.161003108,1.505700573,0.801073441,2.757860506,0.298825498,DB0059010003239_,1.207895494,0.409258287,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,doxazosin,DB00590
,46379,DB00646,10003239,98,3355,42,1958,0.109584128,1.361674699,0.934983444,2.013026688,0.225462793,DB0064610003239_,1.48960013,0.308715339,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,nystatin,DB00646
,46380,DB00704,10003239,116,4240,121,5073,0.321953212,1.147003378,0.878340103,1.497266203,0.490256747,DB0070410003239_,0.712826052,0.137152783,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,naltrexone,DB00704
,46381,DB00715,10003239,128,4715,29,2258,0.000132273,2.113561974,1.398497163,3.292581474,0.001012169,DB0071510003239_,6.895659924,0.748374663,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,paroxetine,DB00715
,46384,DB00924,10003239,357,9805,88,4163,3.05784829742073e-06,1.722383036,1.356297869,2.206685447,3.85494208622081e-05,DB0092410003239_,10.16356948,0.543708818,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,46385,DB00950,10003239,143,4575,36,2020,0.002220979,1.753726165,1.204474557,2.612887529,0.010596047,DB0095010003239_,4.547274314,0.561742761,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fexofenadine,DB00950
,46389,DB01060,10003239,155,8432,82,4999,0.416949341,1.120661959,0.849979263,1.486555514,0.586085908,DB0106010003239_,0.5342889,0.113919546,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,amoxicillin,DB01060
,46391,DB01142,10003239,45,1695,15,769,0.327113194,1.360943355,0.739084311,2.64539892,0.495528935,DB0114210003239_,0.702129532,0.308178103,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,doxepin,DB01142
,46394,DB01224,10003239,99,8009,28,5889,2.04717315599072e-06,2.599611245,1.691536963,4.114677457,2.70469697940266e-05,DB0122410003239_,10.51793558,0.955361913,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,quetiapine,DB01224
,46406,DB00316,10005956,74,65400,35,36918,0.425484799,1.193472886,0.787976426,1.839278901,0.594222833,DB0031610005956_,0.520500891,0.176867448,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,46412,DB00399,10005956,36,6956,24,4974,0.895722479,1.07260684,0.621621591,1.881837951,0.956162421,DB0039910005956_,0.044827484,0.070091985,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,46415,DB00451,10005956,69,47202,9,15410,0.005503455,2.503020283,1.244446917,5.704899208,0.022090297,DB0045110005956_,3.812616838,0.917498116,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,46453,DB00169,10016454,220,38471,28,18147,3.11280855620341e-14,3.70588516,2.493389648,5.708634535,1.70814557202101e-12,DB0016910016454_,27.09561279,1.30992214,female,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,46457,DB00316,10016454,102,65372,46,36907,0.230505053,1.25190473,0.875352503,1.814403245,0.386522872,DB0031610016454_,0.950564235,0.224666176,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,46460,DB00381,10016454,52,29308,16,22871,0.000823073,2.53610457,1.424920444,4.760238937,0.004688319,DB0038110016454_,5.362681153,0.93062927,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,46462,DB00399,10016454,65,6927,16,4982,3.64870844196778e-05,2.921535065,1.668759631,5.417265995,0.000337046,DB0039910016454_,7.995292576,1.072109185,female,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,zoledronic acid,DB00399
,46611,DB00169,10018735,50,38641,10,18165,0.011911009,2.350452478,1.177753609,5.199945417,0.040925603,DB0016910018735_,3.195999425,0.854607853,NA,10018735,Groin pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,46615,DB00316,10018735,47,65427,23,36930,0.620208959,1.153415279,0.686360757,1.99050003,0.760736017,DB0031610018735_,0.273468871,0.142727349,NA,10018735,Groin pain,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,46624,DB00451,10018735,42,47229,9,15410,0.328369644,1.522605375,0.730360029,3.558442776,0.496945395,DB0045110018735_,0.699275129,0.42042293,NA,10018735,Groin pain,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,46663,DB00115,10018852,31,18394,20,10452,0.663769067,0.880762461,0.486006919,1.631259129,0.795203843,DB0011510018852_,0.229156791,-0.126967314,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,cyanocobalamin,DB00115
,46665,DB00169,10018852,53,38638,37,18138,0.070066534,0.672427646,0.433442747,1.053061613,0.161361444,DB0016910018852_,1.824108435,-0.396860762,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,46669,DB00316,10018852,93,65381,94,36859,9.08319393034448e-05,0.55779188,0.414071881,0.751234684,0.00073496,DB0031610018852_,7.215694497,-0.583769361,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,46673,DB00381,10018852,38,29322,46,22841,0.047483086,0.643513751,0.407296688,1.011282017,0.120367724,DB0038110018852_,2.117203859,-0.440811884,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,46695,DB00904,10018852,29,23040,30,14426,0.060437811,0.605288376,0.350382563,1.044135979,0.144202592,DB0090410018852_,1.936536077,-0.50205028,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,ondansetron,DB00904
,46718,DB00169,10026865,37,38654,19,18156,0.774888405,0.914694077,0.512550687,1.684262573,0.877304578,DB0016910026865_,0.130901052,-0.089165612,NA,10026865,Mass,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,46730,DB00451,10026865,64,47207,12,15407,0.082854615,1.740562165,0.930644681,3.544409443,0.183158137,DB0045110026865_,1.697405364,0.554208144,NA,10026865,Mass,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,46931,DB00370,10033371,129,4412,70,3593,0.007425028,1.500691891,1.109322691,2.044406686,0.02806743,DB0037010033371_,3.573145463,0.405926262,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,46932,DB00402,10033371,54,1298,20,676,0.213364629,1.405942088,0.819940524,2.501245353,0.36546382,DB0040210033371_,1.006587991,0.340707603,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,eszopiclone,DB00402
,46933,DB00410,10033371,100,1505,29,980,8.64251681834152e-05,2.244753692,1.458858943,3.549680988,0.000704289,DB0041010033371_,7.258321169,0.808595801,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,mupirocin,DB00410
,46938,DB00590,10033371,17,759,42,1910,1,1.018564357,0.540093782,1.841427719,1,DB0059010033371_,0,0.018394143,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,doxazosin,DB00590
,46939,DB00646,10033371,174,3279,35,1965,1.62830566172793e-10,2.97870082,2.052149406,4.433469797,5.13189620126123e-09,DB0064610033371_,19.08779062,1.091487239,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,46940,DB00698,10033371,129,3019,9,420,0.044351417,1.993730018,1.00780493,4.493399277,0.114303068,DB0069810033371_,2.168901863,0.690007265,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,nitrofurantoin,DB00698
,46941,DB00704,10033371,240,4116,271,4923,0.552948104,1.05920864,0.882093648,1.271372723,0.706643374,DB0070410033371_,0.347229162,0.057522063,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,46943,DB00715,10033371,167,4676,50,2237,0.00386256,1.597760852,1.153442817,2.247030905,0.016577252,DB0071510033371_,4.099723876,0.468603181,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,46944,DB00737,10033371,131,2670,17,915,4.12977435502583e-05,2.640071173,1.576557445,4.696717557,0.000374831,DB0073710033371_,7.889034735,0.970805876,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,meclizine,DB00737
,46947,DB00950,10033371,172,4546,40,2016,0.000139621,1.906748416,1.338966793,2.773134253,0.001060525,DB0095010033371_,6.848991569,0.645399391,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,46950,DB01068,10033371,586,13177,178,6662,1.42452876756168e-09,1.664392389,1.401183337,1.984834476,3.82860313449475e-08,DB0106810033371_,17.07818072,0.509460125,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,46952,DB01142,10033371,62,1678,18,766,0.10996555,1.572116802,0.910477664,2.844179253,0.226010203,DB0114210033371_,1.487175136,0.452422993,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,doxepin,DB01142
,46953,DB01162,10033371,6,267,44,1658,0.837385226,0.846849969,0.292035541,2.021400359,0.916179909,DB0116210033371_,0.087542527,-0.166231732,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,terazosin,DB01162
,46955,DB01432,10033371,40,1251,17,653,0.571344226,1.228028155,0.674396189,2.329298505,0.72156175,DB0143210033371_,0.326337319,0.205409757,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,cholestyramine,DB01432
,46966,DB00316,10034156,28,65446,33,36920,0.004729447,0.478649221,0.278600295,0.817002589,0.019558453,DB0031610034156_,3.934347726,-0.736787264,NA,10034156,Pathological fracture,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,47064,DB00126,10048334,51,10120,14,5931,0.009719463,2.134867114,1.162740199,4.179761348,0.034791784,DB0012610048334_,3.358374001,0.758404403,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,47065,DB00169,10048334,225,38466,65,18110,0.000389681,1.629698056,1.230834157,2.183506997,0.002509249,DB0016910048334_,5.987771871,0.488394756,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,47071,DB00381,10048334,84,29276,38,22849,0.004569213,1.725219727,1.162329189,2.603215008,0.018998933,DB0038110048334_,3.963372485,0.54535442,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,47076,DB00451,10048334,190,47081,30,15389,7.97056101705109e-05,2.069982582,1.402694335,3.154081795,0.000656862,DB0045110048334_,7.328036314,0.727540193,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,47078,DB00476,10048334,84,17173,21,6156,0.149750531,1.433819348,0.879588484,2.438314688,0.283618021,DB0047610048334_,1.260126943,0.360341756,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,47088,DB00704,10048334,27,4329,34,5160,0.897697313,0.946550469,0.54838475,1.61912529,0.956338178,DB0070410048334_,0.044643686,-0.054930988,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,naltrexone,DB00704
,47093,DB00904,10048334,49,23020,28,14428,0.726746118,1.096841523,0.675509428,1.813364889,0.84015137,DB0090410048334_,0.174173201,0.092434707,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,47096,DB00924,10048334,50,10112,11,4240,0.049404487,1.90585289,0.978133107,4.063522301,0.123900099,DB0092410048334_,2.088279695,0.64492962,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,47102,DB01068,10048334,66,13697,29,6811,0.662493024,1.131686413,0.720177873,1.818713881,0.794254303,DB0106810048334_,0.230351588,0.123708921,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,47114,DB00115,10050256,41,18384,24,10448,0.897906353,0.970860498,0.572501824,1.680862435,0.956338178,DB0011510050256_,0.044643686,-0.029572489,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,47116,DB00169,10050256,85,38606,37,18138,0.770833194,1.079321066,0.72520983,1.634449711,0.874483718,DB0016910050256_,0.134121604,0.076332201,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,47120,DB00316,10050256,115,65359,50,36903,0.143921142,1.298636589,0.923794838,1.848645525,0.275405301,DB0031610050256_,1.289511446,0.261314936,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,47124,DB00381,10050256,65,29295,32,22855,0.031756773,1.584698445,1.022278968,2.501976145,0.088551082,DB0038110050256_,2.4241757,0.460394134,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,47128,DB00451,10050256,93,47178,29,15390,0.916294329,1.04615557,0.682717926,1.647380983,0.962623242,DB0045110050256_,0.038093178,0.045122083,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,47130,DB00476,10050256,42,17215,9,6168,0.202242233,1.672079804,0.801644248,3.908957257,0.351657843,DB0047610050256_,1.045096612,0.514068243,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,47144,DB00904,10050256,37,23032,14,14442,0.114297091,1.657156333,0.87466541,3.319369059,0.232576365,DB0090410050256_,1.458536656,0.505103081,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,47153,DB01068,10050256,40,13723,28,6812,0.196450805,0.70912232,0.426328342,1.194676583,0.34471841,DB0106810050256_,1.065027399,-0.343727243,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,47272,DB01075,10033295,268,19680,99,10998,0.000359153,1.512804057,1.195488612,1.927177652,0.002343968,DB0107510033295_,6.055910001,0.41396492,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,47273,DB00331,10045555,77,24869,39,20713,0.011492077,1.644391075,1.104208947,2.484344487,0.039803563,DB0033110045555_,3.22379885,0.497370148,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,metformin,DB00331
,47274,DB00193,10010071,56,19264,9,8693,0.001858424,2.807733445,1.377520239,6.459743206,0.009159233,DB0019310010071_,4.692992854,1.032377555,female,10010071,Coma,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,47276,DB00924,10021097,129,10033,80,4171,0.005906132,0.670381611,0.502067527,0.899693753,0.023379921,DB0092410021097_,3.755877683,-0.399908159,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,cyclobenzaprine,DB00924
,47277,DB00193,10027417,42,19278,13,8689,0.306736169,1.456183407,0.766292442,2.958181674,0.473780532,DB0019310027417_,0.747011076,0.375818908,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,tramadol,DB00193
,47279,DB00193,10033295,157,19163,97,8605,0.016917455,0.726794273,0.55996771,0.947361392,0.054198951,DB0019310033295_,2.915093727,-0.319111822,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,47280,DB00924,10033295,90,10072,58,4193,0.011067519,0.646008068,0.458351965,0.916664415,0.038582192,DB0092410033295_,3.254964459,-0.436943285,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,47282,DB00316,10038678,186,65288,82,36871,0.064716837,1.281024239,0.982438939,1.682598383,0.151950161,DB0031610038678_,1.884202698,0.247659944,NA,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,47283,DB00924,10038678,38,10124,13,4238,0.644844069,1.223595465,0.636779204,2.505858651,0.780709787,DB0092410038678_,0.24755179,0.201793627,NA,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,47294,DB00641,10046306,115,14009,36,12439,5.84281095224637e-09,2.836185793,1.933878172,4.250911621,1.38431868772092e-07,DB0064110046306_,15.79288755,1.042460119,female,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,simvastatin,DB00641
,47295,DB00788,10046306,73,9283,25,5036,0.055311543,1.584044214,0.992189288,2.607973521,0.134882127,DB0078810046306_,2.003354014,0.459981206,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,naproxen,DB00788
,47297,DB14500,10046306,75,7734,11,4062,9.88654317806949e-06,3.580705028,1.888378001,7.488856155,0.000107539,DB1450010046306_,9.137657778,1.275559716,female,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,potassium,DB14500
,47315,DB00316,10019663,115,65359,93,36860,0.011261563,0.697402369,0.525815261,0.927000799,0.039126321,DB0031610019663_,3.24095988,-0.360392748,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,47326,DB00331,10019465,34,24912,17,20735,0.091848423,1.66463741,0.904225691,3.178282647,0.19821166,DB0033110019465_,1.618419829,0.509607328,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,metformin,DB00331
,47327,DB00489,10003549,43,1040,34,1100,0.245944208,1.337488195,0.825963521,2.18105492,0.404900633,DB0048910003549_,0.904113593,0.290793373,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sotalol,DB00489
,47329,DB00421,10003988,202,8701,65,5187,9.10904753666751e-06,1.852538502,1.391156534,2.494736079,0.00010016,DB0042110003988_,9.208746518,0.616556862,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,spironolactone,DB00421
,47332,DB00421,10017955,121,8782,125,5127,1.01465686686317e-05,0.565176307,0.435398708,0.733359669,0.000110003,DB0042110017955_,9.115001855,-0.570617548,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,47333,DB00489,10021097,31,1052,56,1078,0.011940227,0.56739792,0.350564633,0.90348421,0.040996523,DB0048910021097_,3.194268031,-0.566694423,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sotalol,DB00489
,47337,DB00722,10040560,52,25351,90,25942,0.002408167,0.591256553,0.41173486,0.841363792,0.01132153,DB0072210040560_,4.481049059,-0.525505256,NA,10040560,Shock,10047065,Vascular disorders,Vasc,lisinopril,DB00722
,47344,DB00316,10001497,269,65205,170,36783,0.252197905,0.892630221,0.733600201,1.088531411,0.412318987,DB0031610001497_,0.88595799,-0.11358287,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,47351,DB00788,10000059,152,9204,48,5013,0.000760112,1.724678987,1.236729224,2.443211622,0.004382439,DB0078810000059_,5.430149863,0.545040939,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,47352,DB00514,10022523,42,2124,35,1501,0.485059805,0.848064382,0.525812217,1.375356388,0.649191526,DB0051410022523_,0.432027496,-0.164798724,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,dextromethorphan,DB00514
,47355,DB00514,10047700,62,2104,30,1506,0.08670009,1.479125647,0.936635682,2.382149795,0.189553908,DB0051410047700_,1.663081822,0.391451134,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dextromethorphan,DB00514
,47357,DB00421,10013700,236,8667,142,5110,0.871429055,0.979878373,0.790015973,1.218899944,0.943312441,DB0042110013700_,0.058357724,-0.020326824,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,spironolactone,DB00421
,47358,DB00437,10013700,129,6792,82,11464,4.1683498131745e-12,2.655166807,1.99417198,3.552077086,1.70000116119925e-10,DB0043710013700_,22.495222,0.97650748,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,allopurinol,DB00437
,47361,DB00695,10013700,412,27637,153,20375,5.86846939183209e-14,1.985195831,1.643537933,2.407980319,3.10055714501119e-12,DB0069510013700_,26.4994393,0.685717565,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,furosemide,DB00695
,47363,DB14500,10013700,109,7700,22,4051,1.07050239442255e-05,2.606424957,1.634441532,4.336584454,0.000115132,DB1450010013700_,9.069428359,0.957979534,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,potassium,DB14500
,47364,DB00046,10021143,39,5420,41,4651,0.370366306,0.816277726,0.511832724,1.299853713,0.540012667,DB0004610021143_,0.616162682,-0.203000631,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin lispro,DB00046
,47365,DB00437,10021143,70,6851,123,11423,0.765235069,0.948895466,0.696115596,1.284859864,0.870483106,DB0043710021143_,0.138706927,-0.052456638,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,47366,DB01076,10021143,144,25603,153,25430,0.600525554,0.934789447,0.738813838,1.182290417,0.744900507,DB0107610021143_,0.294504618,-0.067433966,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,47368,DB01118,10021143,57,3006,52,4657,0.007415005,1.69802201,1.142003882,2.529690906,0.028035157,DB0111810021143_,3.574295959,0.52946405,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,47369,DB01136,10021143,66,9818,61,11054,0.28513091,1.218162643,0.845948887,1.756619062,0.449728513,DB0113610021143_,0.799111182,0.197343693,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,47370,DB14500,10021143,58,7751,39,4034,0.23738346,0.774040346,0.506047527,1.195287682,0.394756872,DB1450010021143_,0.929485218,-0.25613128,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,47372,DB00404,10028997,36,19856,22,9840,0.48526331,0.810953179,0.464024759,1.447872427,0.649331641,DB0040410028997_,0.431811689,-0.209544959,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,alprazolam,DB00404
,47375,DB00451,10028997,65,47206,29,15390,0.186428565,0.730733869,0.464740905,1.174841314,0.33199694,DB0045110028997_,1.102629528,-0.31370595,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levothyroxine,DB00451
,47381,DB00046,10030095,46,5413,30,4662,0.249975304,1.320560751,0.814424054,2.170500686,0.40961292,DB0004610030095_,0.892542662,0.278056458,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,47382,DB00404,10030095,98,19794,33,9829,0.062332298,1.474628409,0.984037366,2.261167848,0.14780374,DB0040410030095_,1.911869966,0.388406032,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,47384,DB01136,10030095,83,9801,80,11035,0.344820895,1.16811647,0.847720081,1.610486366,0.514276965,DB0113610030095_,0.664993317,0.155392597,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,47385,DB00046,10037844,68,5391,60,4632,0.928980562,0.973766293,0.676365911,1.404950601,0.970576706,DB0004610037844_,0.029864842,-0.02658395,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,insulin lispro,DB00046
,47386,DB00421,10037844,232,8671,98,5154,0.004686008,1.407106768,1.103504308,1.805185093,0.019413935,DB0042110037844_,3.941764172,0.341535659,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,spironolactone,DB00421
,47387,DB00524,10037844,32,1545,28,1316,1,0.97346402,0.564446347,1.687626699,1,DB0052410037844_,0,-0.026894414,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,metolazone,DB00524
,47388,DB00559,10037844,88,9571,32,3274,0.752934242,0.940705773,0.619869921,1.46045415,0.860884621,DB0055910037844_,0.14979479,-0.061124863,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,bosentan,DB00559
,47389,DB01101,10037844,250,7339,82,3826,0.000255623,1.589344176,1.229694622,2.071976101,0.001768868,DB0110110037844_,6.337415757,0.463321463,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,capecitabine,DB01101
,47392,DB00421,10039163,113,8790,40,5212,0.005312099,1.675016228,1.156324753,2.470702319,0.021468101,DB0042110039163_,3.841187139,0.515822853,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,spironolactone,DB00421
,47394,DB00451,10039163,93,47178,18,15401,0.04629975,1.686555324,1.010351997,2.970938026,0.118085478,DB0045110039163_,2.136346524,0.522688179,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,47395,DB00524,10039163,66,1511,21,1323,2.59333289315905e-05,2.750794849,1.651188371,4.761041379,0.000249234,DB0052410039163_,8.297116988,1.011889906,female,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,metolazone,DB00524
,47396,DB00695,10039163,198,27851,66,20462,6.33884586534317e-09,2.204031288,1.659184454,2.959916749,1.4903091553716e-07,DB0069510039163_,15.71911207,0.790288087,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,furosemide,DB00695
,47397,DB01076,10039163,38,25709,25,25558,0.129805872,1.511052517,0.888413985,2.612674184,0.255375724,DB0107610039163_,1.365019392,0.412806439,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,47402,DB00421,10042674,143,8760,39,5213,6.23633956998928e-06,2.181890866,1.51911341,3.19988705,7.18272058668526e-05,DB0042110042674_,9.541247242,0.78019187,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,47403,DB00437,10042674,69,6852,61,11485,0.000352119,1.895960792,1.32202696,2.724701722,0.002304358,DB0043710042674_,6.072952984,0.639725724,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,47404,DB00524,10042674,49,1528,20,1324,0.00463312,2.122328563,1.231097495,3.78991363,0.019231198,DB0052410042674_,3.951221443,0.752513865,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,47405,DB00559,10042674,113,9546,33,3273,0.446518176,1.174038657,0.788644795,1.790685199,0.614343755,DB0055910042674_,0.487200646,0.160449649,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,47406,DB00695,10042674,422,27627,156,20372,2.1356598065893e-14,1.994704344,1.654626894,2.414687472,1.20076616077433e-12,DB0069510042674_,27.4480613,0.690495841,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,47407,DB01076,10042674,195,25552,126,25457,0.00016714,1.541843679,1.225226481,1.946026713,0.001238237,DB0107610042674_,6.694066628,0.432978895,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,47408,DB01101,10042674,37,7552,19,3889,1,1.002822299,0.561264819,1.848799114,1,DB0110110042674_,0,0.002818324,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,47410,DB14500,10042674,101,7708,39,4034,0.127463276,1.355317329,0.925989158,2.018973914,0.252030858,DB1450010042674_,1.378203747,0.304035618,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,47411,DB00046,10047899,104,5355,48,4644,0.000284051,1.878874248,1.319098108,2.709633936,0.001929524,DB0004610047899_,6.250482181,0.630672793,NA,10047899,Weight increased,10022891,Investigations,Inv,insulin lispro,DB00046
,47413,DB01136,10047899,185,9699,117,10998,6.94797527943417e-07,1.79289918,1.412378587,2.28352141,1.03883691820209e-05,DB0113610047899_,11.47482373,0.583833963,NA,10047899,Weight increased,10022891,Investigations,Inv,carvedilol,DB01136
,47417,DB00451,10054786,60,47211,13,15406,0.220405939,1.506058465,0.817367926,2.991710081,0.373950854,DB0045110054786_,0.983630897,0.40949595,NA,10054786,Skin burning sensation,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,47440,DB00421,10064911,224,8679,48,5204,2.30415572542953e-12,2.797982383,2.036521275,3.913761087,9.79219615891920e-11,DB0042110064911_,23.04685026,1.02889858,female,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,47441,DB00437,10064911,42,6879,26,11520,7.22055133222018e-05,2.705079208,1.618665539,4.59963736,0.000602611,DB0043710064911_,7.414239429,0.995131194,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,47442,DB00451,10064911,186,47085,19,15400,3.25484867555337e-08,3.201893563,1.992511096,5.440576042,6.5308165982382e-07,DB0045110064911_,14.24156366,1.163742373,female,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,47443,DB00524,10064911,98,1479,34,1310,1.59728753749665e-06,2.552075182,1.698377415,3.917880416,2.17819470418156e-05,DB0052410064911_,10.73442905,0.936906825,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metolazone,DB00524
,47444,DB00695,10064911,376,27673,109,20419,4.31752358440478e-20,2.545224019,2.049627101,3.182363975,4.49449930360712e-18,DB0069510064911_,39.9436774,0.934218669,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,47445,DB01076,10064911,85,25662,42,25541,0.000168614,2.014229415,1.375478755,2.989863862,0.001248107,DB0107610064911_,6.686127529,0.700236698,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,47449,DB14500,10064911,78,7731,20,4053,0.003672329,2.044478082,1.236094417,3.533894233,0.015929892,DB1450010064911_,4.139557945,0.71514254,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,47464,DB00820,10062355,319,11596,97,5719,2.21851432165648e-05,1.6218845,1.285277847,2.062008084,0.000218158,DB0082010062355_,8.43029072,0.483588745,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,47473,DB00654,10011224,61,3755,37,2561,0.605517728,1.124429696,0.732934897,1.745919173,0.748619905,DB0065410011224_,0.289523894,0.117275971,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,latanoprost,DB00654
,47474,DB00654,10022000,31,3785,19,2579,0.773756173,1.111722999,0.606974829,2.087636926,0.876475726,DB0065410022000_,0.131846269,0.105911063,NA,10022000,Influenza,10021881,Infections and infestations,Infec,latanoprost,DB00654
,47478,DB00230,10013082,108,19566,52,8599,0.605774063,0.91278689,0.649150461,1.297777571,0.748831155,DB0023010013082_,0.289241749,-0.091252843,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,47487,DB00230,10060933,53,19621,21,8630,0.800587375,1.110052652,0.657845422,1.938791029,0.892219336,DB0023010060933_,0.114043285,0.104407448,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,47491,DB00811,10003988,41,2757,47,4109,0.230028292,1.300058342,0.831441154,2.025628316,0.386000721,DB0081110003988_,0.951916042,0.262409142,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ribavirin,DB00811
,47492,DB01156,10003988,205,13417,67,6261,0.012511427,1.427787779,1.076727883,1.91378107,0.042568488,DB0115610003988_,3.15664101,0.356126239,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,47493,DB00316,10020993,222,65252,156,36797,0.036444536,0.80251856,0.650679795,0.99170563,0.098457744,DB0031610020993_,2.318127813,-0.220000296,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,47494,DB00338,10020993,80,33594,51,22221,0.858698019,1.037582768,0.721007558,1.5051165,0.932799372,DB0033810020993_,0.069565137,0.036893747,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,47498,DB00338,10029354,237,33437,212,22060,0.001391281,0.737566279,0.609717378,0.892646074,0.007223669,DB0033810029354_,4.930392274,-0.304399325,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,omeprazole,DB00338
,47499,DB01156,10029354,39,13583,31,6297,0.028336668,0.583240981,0.354261099,0.967765026,0.081016947,DB0115610029354_,2.513096918,-0.539154831,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,bupropion,DB01156
,47501,DB00175,10013952,47,8084,18,6088,0.016339046,1.966305631,1.119350996,3.60123769,0.052680795,DB0017510013952_,2.94350432,0.676156468,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,47512,DB01240,10017955,97,5654,24,1552,0.738085953,1.109405235,0.700886763,1.820901358,0.849171176,DB0124010017955_,0.163494492,0.103824047,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,47513,DB00421,10022000,124,8779,32,5220,8.42431900467609e-06,2.303954324,1.548747769,3.518679742,9.35501584444069e-05,DB0042110022000_,9.277012812,0.834626918,NA,10022000,Influenza,10021881,Infections and infestations,Infec,spironolactone,DB00421
,47514,DB00451,10022000,490,46781,140,15279,0.177476945,1.143119964,0.944615099,1.390608948,0.320628303,DB0045110022000_,1.13747276,0.133761335,NA,10022000,Influenza,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,47515,DB00635,10022000,416,32637,199,23595,1.41806999675073e-06,1.511285236,1.272179932,1.800084661,1.95932212045067e-05,DB0063510022000_,10.84032691,0.412960439,NA,10022000,Influenza,10021881,Infections and infestations,Infec,prednisone,DB00635
,47516,DB01069,10022000,92,6608,17,2378,0.008617251,1.947450503,1.149601312,3.494033472,0.031610501,DB0106910022000_,3.454265914,0.666521083,NA,10022000,Influenza,10021881,Infections and infestations,Infec,promethazine,DB01069
,47517,DB00203,10035528,81,13797,30,8908,0.008365233,1.743206187,1.132698352,2.748592562,0.03085171,DB0020310035528_,3.478563096,0.555726054,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,sildenafil,DB00203
,47519,DB00635,10035528,282,32771,253,23541,0.012017205,0.800698163,0.672716273,0.95338134,0.041193564,DB0063510035528_,3.18947326,-0.222271228,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,prednisone,DB00635
,47520,DB00682,10035528,165,19294,170,16194,0.068864707,0.814649819,0.652849567,1.01630136,0.159277472,DB0068210035528_,1.83710749,-0.204996928,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,warfarin,DB00682
,47521,DB01069,10035528,65,6635,33,2362,0.106239805,0.701223987,0.453125209,1.103859229,0.220548531,DB0106910035528_,1.511637511,-0.354927918,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,promethazine,DB01069
,47522,DB01240,10035528,80,5671,15,1561,0.208280789,1.467967349,0.836116191,2.752350954,0.359147214,DB0124010035528_,1.024022909,0.383878688,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,epoprostenol,DB01240
,47523,DB00635,10064911,129,32924,34,23760,1.68916773400999e-08,2.737975263,1.863267148,4.123616045,3.59657949683698e-07,DB0063510064911_,14.8381124,1.007218692,female,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,47537,DB05259,10011224,53,11217,15,2713,0.542917491,0.854569574,0.473721461,1.635122437,0.698118538,DB0525910011224_,0.359366365,-0.157157359,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glatiramer,DB05259
,47538,DB05259,10022067,99,11171,25,2703,0.820325354,0.958182846,0.611398415,1.554499294,0.904305148,DB0525910022067_,0.100588423,-0.042716657,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,47539,DB05259,10022112,96,11174,13,2715,0.051154577,1.79418818,0.99910431,3.497063317,0.127208898,DB0525910022112_,2.061924676,0.584552652,NA,10022112,Injection site warmth,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,47544,DB00682,10037400,350,19109,151,16213,9.13960772522382e-13,1.966529358,1.618376203,2.398796496,4.12419895377696e-11,DB0068210037400_,23.91156422,0.676270242,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,47546,DB09053,10061818,101,2184,208,3844,0.2244391,0.85464533,0.66310341,1.095869688,0.379076739,DB0905310061818_,0.970016616,-0.157068715,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,ibrutinib,DB09053
,47549,DB06186,10003827,12,2197,43,3603,0.016718775,0.457719089,0.219227945,0.885961458,0.053673649,DB0618610003827_,2.924833114,-0.781499626,NA,10003827,Autoimmune hepatitis,10019805,Hepatobiliary disorders,Hepat,ipilimumab,DB06186
,47550,DB00316,10009887,192,65282,109,36844,0.952155297,0.994140309,0.781570362,1.269865361,0.990184249,DB0031610009887_,0.009864243,-0.005876927,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,47551,DB00706,10037844,14,1061,366,15559,0.032283066,0.560978819,0.302542382,0.95778395,0.089724968,DB0070610037844_,2.4110062,-0.578072129,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,tamsulosin,DB00706
,47567,DB00169,10024670,63,38628,26,18149,0.649608766,1.138450713,0.710152675,1.874061509,0.784352715,DB0016910024670_,0.242896469,0.129668315,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,cholecalciferol,DB00169
,47569,DB00108,10011781,49,10145,14,3281,0.769922997,1.131925363,0.614005962,2.223135528,0.873962496,DB0010810011781_,0.134717815,0.123920044,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,natalizumab,DB00108
,47570,DB00108,10011985,56,10138,37,3258,0.000980682,0.486404296,0.314862421,0.759460716,0.005417091,DB0010810011985_,5.218196377,-0.720715116,NA,10011985,Decubitus ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,natalizumab,DB00108
,47571,DB00169,10001497,76,38615,65,18110,0.00053754,0.548333137,0.388393668,0.77614398,0.003275968,DB0016910001497_,5.721141862,-0.600872263,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,47573,DB00281,10001497,54,11404,36,5635,0.177815222,0.741172389,0.476694531,1.164855701,0.321094836,DB0028110001497_,1.136018759,-0.299522037,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,lidocaine,DB00281
,47575,DB00381,10001497,55,29305,62,22825,0.049956472,0.690953627,0.471493724,1.010207502,0.124920884,DB0038110001497_,2.080074668,-0.369682567,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,47576,DB00404,10001497,121,19771,65,9797,0.585627338,0.922440897,0.676154767,1.268247795,0.733044896,DB0040410001497_,0.31054833,-0.080731973,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,47577,DB00512,10001497,16,4721,44,5054,0.001022099,0.389346591,0.20476766,0.704872176,0.00560523,DB0051210001497_,5.18405514,-0.943285352,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,vancomycin,DB00512
,47578,DB00557,10001497,48,5939,32,3035,0.285295706,0.766591219,0.478915941,1.241850276,0.449863381,DB0055710001497_,0.798811341,-0.26580158,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,hydroxyzine,DB00557
,47581,DB00904,10001497,73,22996,53,14403,0.410902045,0.862683454,0.597032769,1.253794949,0.580230833,DB0090410001497_,0.544329267,-0.147707452,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,47588,DB00184,10033295,51,1243,28,954,0.167113844,1.397740643,0.857463699,2.320738552,0.306970011,DB0018410033295_,1.181005219,0.334857107,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,nicotine,DB00184
,47589,DB00281,10033295,71,11387,53,5618,0.027204476,0.660930108,0.455874533,0.963438322,0.07844977,DB0028110033295_,2.545296728,-0.414107182,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lidocaine,DB00281
,47590,DB00285,10033295,194,10757,63,3655,0.828200808,1.046268862,0.781528227,1.416935706,0.909674858,DB0028510033295_,0.094668042,0.045230371,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,47592,DB00557,10033295,88,5899,72,2995,0.00315495,0.620554759,0.447803007,0.862307554,0.014096186,DB0055710033295_,4.261851012,-0.477141428,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxyzine,DB00557
,47594,DB00706,10033295,7,1068,90,15835,0.673739837,1.153182753,0.449634602,2.483361847,0.802138219,DB0070610033295_,0.220474343,0.142525731,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,tamsulosin,DB00706
,47595,DB00904,10033295,82,22987,38,14418,0.133022736,1.353472825,0.910086667,2.045456859,0.259972684,DB0090410033295_,1.347178717,0.302673752,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,47603,DB00213,10040108,30,18865,20,13401,0.886449156,1.065553749,0.585165751,1.980507632,0.952754032,DB0021310040108_,0.048398507,0.063494616,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,47605,DB00285,10040108,82,10869,41,3677,0.047528745,0.676623079,0.458701652,1.011865325,0.120448617,DB0028510040108_,2.116532032,-0.390640913,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,47606,DB00327,10040108,38,6100,67,4195,3.06682518749263e-06,0.390075742,0.254332043,0.590578252,3.86485607047944e-05,DB0032710040108_,10.16100102,-0.94141435,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,47609,DB00404,10040108,22,19870,38,9824,2.68986849393681e-06,0.286252643,0.161166377,0.496789331,3.43887127252573e-05,DB0040410040108_,10.27778217,-1.250880492,male,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,47611,DB00512,10040108,12,4725,49,5049,7.09033847291599e-06,0.261735858,0.126528501,0.500034518,8.03143920536939e-05,DB0051210040108_,9.429561725,-1.34041946,male,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,vancomycin,DB00512
,47615,DB00904,10040108,103,22966,132,14324,5.4346387586242e-08,0.486679592,0.372098581,0.635138521,1.04345858123037e-06,DB0090410040108_,13.7729698,-0.720149294,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,47622,DB00281,10048294,84,11374,47,5624,0.514595099,0.883729614,0.610270611,1.29320016,0.674502315,DB0028110048294_,0.393780172,-0.123604129,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,lidocaine,DB00281
,47623,DB00285,10048294,53,10898,29,3689,0.041527683,0.618665216,0.385608767,1.010799306,0.108807331,DB0028510048294_,2.218176564,-0.480190998,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,47624,DB00335,10048294,39,8427,37,5428,0.099274877,0.678975645,0.42118898,1.096264529,0.20976207,DB0033510048294_,1.561781391,-0.387170021,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,atenolol,DB00335
,47625,DB00381,10048294,136,29224,122,22765,0.258402357,0.868378654,0.674643245,1.118785699,0.419395243,DB0038110048294_,0.868941504,-0.141127422,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,47626,DB00437,10048294,52,6869,76,11470,0.464676086,1.142495793,0.785996533,1.649444328,0.631688393,DB0043710048294_,0.459359055,0.133215161,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,allopurinol,DB00437
,47627,DB00512,10048294,48,4689,75,5023,0.045561884,0.685616007,0.465941937,1.000449487,0.11663931,DB0051210048294_,2.148668925,-0.377437565,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,vancomycin,DB00512
,47628,DB00557,10048294,34,5953,21,3046,0.479387595,0.8284565,0.466258996,1.504889707,0.644411171,DB0055710048294_,0.439418293,-0.188190948,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,hydroxyzine,DB00557
,47631,DB01109,10048294,38,4374,49,4221,0.196506395,0.748411209,0.475627536,1.169647656,0.344746911,DB0110910048294_,1.064944723,-0.289802707,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,heparin,DB01109
,47635,DB09153,10048294,48,7751,42,5657,0.393876062,0.83411956,0.538903515,1.295477085,0.563819957,DB0915310048294_,0.573020303,-0.18137853,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,sodium chloride,DB09153
,47636,DB00169,10064687,51,38640,24,18151,1,0.998211079,0.60299662,1.696204593,1,DB0016910064687_,0,-0.001790523,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,47638,DB00213,10064687,36,18859,27,13394,0.898319793,0.946977444,0.558776316,1.622633056,0.956365087,DB0021310064687_,0.044615548,-0.054480004,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,47642,DB00316,10064687,76,65398,57,36896,0.104691608,0.752257624,0.526461954,1.080125132,0.218051793,DB0031610064687_,1.52302266,-0.284676428,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,47645,DB00381,10064687,33,29327,22,22865,0.589862256,1.16947349,0.661473781,2.106188395,0.736574711,DB0038110064687_,0.305744607,0.156553639,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,47653,DB00904,10064687,62,23007,36,14420,0.756008205,1.079438607,0.704244237,1.676816703,0.863197762,DB0090410064687_,0.147111458,0.076441098,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,ondansetron,DB00904
,47659,DB09153,10064687,43,7756,24,5675,0.322251842,1.310920861,0.776826624,2.261185625,0.49060293,DB0915310064687_,0.712120175,0.270729837,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,47667,DB08896,10005191,64,759,70,970,0.416720412,1.168353175,0.807895801,1.687293623,0.585936452,DB0889610005191_,0.53454394,0.155595214,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,regorafenib,DB08896
,47669,DB08896,10013781,30,793,29,1011,0.351173423,1.318658253,0.75777018,2.29796981,0.520874064,DB0889610013781_,0.652246986,0.276614745,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,regorafenib,DB08896
,47673,DB08896,10020772,55,768,45,995,0.029419622,1.583053433,1.035592863,2.430788792,0.083419068,DB0889610020772_,2.483878364,0.459355535,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,regorafenib,DB08896
,47675,DB08896,10037844,70,753,40,1000,2.73095409730122e-05,2.322996367,1.533942185,3.559005875,0.000261077,DB0889610037844_,8.250695073,0.84285789,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,regorafenib,DB08896
,47677,DB08896,10040844,38,785,52,988,0.744814548,0.919761381,0.58249994,1.441040536,0.854276319,DB0889610040844_,0.15750058,-0.083641011,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,regorafenib,DB08896
,47681,DB01240,10040047,174,5577,60,1516,0.124358975,0.788336482,0.581203427,1.081709638,0.247623104,DB0124010040047_,1.395847429,-0.237830272,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,47682,DB00394,10013573,45,1594,23,771,0.895707757,0.946370046,0.555952745,1.651445116,0.956162421,DB0039410013573_,0.044827484,-0.055121617,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,beclomethasone dipropionate,DB00394
,47684,DB00394,10013709,80,1559,39,755,1,0.993405974,0.662139212,1.511836532,1,DB0039410013709_,0,-0.006615862,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,beclomethasone dipropionate,DB00394
,47685,DB00394,10019211,100,1539,47,747,0.927758704,1.03271135,0.714569072,1.510403799,0.969724129,DB0039410019211_,0.030743651,0.032187722,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,beclomethasone dipropionate,DB00394
,47687,DB00394,10028813,95,1544,22,772,0.000805297,2.158499227,1.333865141,3.635530293,0.004600571,DB0039410028813_,5.381574888,0.769413178,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,beclomethasone dipropionate,DB00394
,47694,DB00480,10056342,54,67374,51,67611,0.770480586,1.062574101,0.711001571,1.589873462,0.874236414,DB0048010056342_,0.134404443,0.060694361,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,47696,DB00682,10056342,30,19429,24,16340,0.891994613,1.051273592,0.593894782,1.879770031,0.955072385,DB0068210056342_,0.045968145,0.050002374,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,47700,DB00559,10003246,51,9608,7,3299,0.015681794,2.501637345,1.128813345,6.540779102,0.051045938,DB0055910003246_,2.975029306,0.916945455,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,bosentan,DB00559
,47701,DB01020,10011906,69,1744,130,1748,2.93017931831022e-05,0.532079106,0.388436784,0.723696985,0.000277899,DB0102010011906_,8.188252099,-0.630963105,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,isosorbide mononitrate,DB01020
,47708,DB00005,10070863,53,128029,43,42376,2.49829702330047e-05,0.407962598,0.267654532,0.624979956,0.000241456,DB0000510070863_,8.328823961,-0.89657978,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,47709,DB01060,10070863,19,8568,39,5042,3.88873899568709e-06,0.286717004,0.156314614,0.508911088,4.73975074085909e-05,DB0106010070863_,9.956940917,-1.249259598,male,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,amoxicillin,DB01060
,47713,DB01164,10056520,55,6469,54,7882,0.288063803,1.240965674,0.83552216,1.843882601,0.453073066,DB0116410056520_,0.791701874,0.215889846,NA,10056520,Catheter site infection,10021881,Infections and infestations,Infec,calcium chloride,DB01164
,47715,DB14726,10050953,81,1936,78,2770,0.017359611,1.485659002,1.068948706,2.065915936,0.055315476,DB1472610050953_,2.894702552,0.395858446,NA,10050953,Lower gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,dabigatran,DB14726
,47717,DB00471,10007559,109,14080,41,5424,1,1.024152148,0.708016199,1.506853206,1,DB0047110007559_,0,0.023865097,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,montelukast,DB00471
,47718,DB00887,10007559,112,2229,100,1715,0.319722851,0.861765025,0.647147723,1.148797483,0.487866278,DB0088710007559_,0.71771393,-0.148772638,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,bumetanide,DB00887
,47719,DB01118,10007559,78,2985,131,4578,0.566244238,0.913171651,0.678240094,1.22278123,0.717634031,DB0111810007559_,0.331795546,-0.090831408,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,amiodarone,DB01118
,47720,DB00563,10040047,296,46350,240,15108,5.26009193712859e-24,0.402017037,0.337582784,0.479124394,7.55527412936748e-22,DB0056310040047_,48.63462617,-0.91126081,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,methotrexate,DB00563
,47721,DB08895,10040047,114,28000,19,6627,0.184332357,1.420051941,0.868138757,2.446919789,0.329336882,DB0889510040047_,1.110674093,0.350693449,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,47722,DB00005,10039580,127,127955,39,42380,0.720187807,1.078555416,0.747938498,1.586760728,0.834846152,DB0000510039580_,0.18050782,0.075622568,NA,10039580,Scar,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,47723,DB00005,10058046,84,127998,30,42389,0.745120496,0.927266702,0.604517936,1.457941731,0.854485157,DB0000510058046_,0.157256147,-0.07551405,NA,10058046,Post procedural complication,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,47726,DB00065,10008479,108,9356,63,4894,0.517201777,0.89673053,0.649884674,1.246253659,0.676847247,DB0006510008479_,0.390309664,-0.108999875,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,47727,DB00065,10020772,95,9369,48,4909,0.860129535,1.037007089,0.724088724,1.502319585,0.934091433,DB0006510020772_,0.068180952,0.036338765,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,infliximab,DB00065
,47729,DB00065,10051792,808,8656,428,4529,0.850978134,0.98775937,0.872564583,1.119307405,0.926516455,DB0006510051792_,0.076323473,-0.012316164,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,infliximab,DB00065
,47732,DB00158,10031009,47,16768,10,8094,0.015570605,2.268650708,1.130586564,5.038511023,0.050765735,DB0015810031009_,2.980533663,0.819185253,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,47733,DB00678,10031009,47,15552,18,10706,0.032045342,1.797446742,1.023774674,3.290394241,0.089199599,DB0067810031009_,2.416878737,0.586367182,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,47734,DB08895,10031009,56,28058,11,6635,0.643834619,1.203862589,0.623643921,2.549689214,0.780122296,DB0889510031009_,0.248304582,0.185535212,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,47735,DB00678,10068319,109,15490,39,10685,0.000289218,1.9278497,1.324833997,2.857743028,0.001957786,DB0067810068319_,6.235941104,0.656405237,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,47736,DB01164,10061138,53,6471,80,7856,0.255067747,0.804308747,0.556479456,1.154280627,0.415741791,DB0116410061138_,0.877690905,-0.21777207,NA,10061138,Fungal peritonitis,10021881,Infections and infestations,Infec,calcium chloride,DB01164
,47737,DB00207,10001551,57,9023,102,5353,1.40182038991886e-11,0.331554501,0.234987694,0.463805804,5.21171838034191e-10,DB0020710001551_,21.37494131,-1.103963077,male,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,azithromycin,DB00207
,47739,DB01137,10001551,30,7742,36,5557,0.044658162,0.598181747,0.355381741,1.000213207,0.114907718,DB0113710001551_,2.163625928,-0.513860647,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,levofloxacin,DB01137
,47740,DB01212,10001551,40,1979,106,1835,5.26137241678805e-09,0.349987705,0.235598802,0.511069953,1.25780058185788e-07,DB0121210001551_,15.88873103,-1.049857253,male,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,ceftriaxone,DB01212
,47741,DB06228,10001551,25,15887,30,16046,0.590002345,0.84167899,0.474414551,1.481235656,0.736679649,DB0622810001551_,0.30560215,-0.172356585,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,rivaroxaban,DB06228
,47743,DB00512,10005364,30,4707,29,5069,0.696962412,1.114028603,0.64501814,1.926771603,0.817691928,DB0051210005364_,0.20126963,0.107982817,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,vancomycin,DB00512
,47748,DB00207,10005483,28,9052,62,5393,2.02830096098089e-09,0.269090326,0.165567306,0.427461518,5.29432877451665e-08,DB0020710005483_,16.75404454,-1.312708172,male,10005483,Blood creatinine increased,10022891,Investigations,Inv,azithromycin,DB00207
,47750,DB01137,10005483,23,7749,45,5548,6.12249795008756e-05,0.365963358,0.211073926,0.618607014,0.000524543,DB0113710005483_,7.552982739,-1.005222066,male,10005483,Blood creatinine increased,10022891,Investigations,Inv,levofloxacin,DB01137
,47751,DB01212,10005483,23,1996,43,1898,0.008911663,0.508710284,0.291430287,0.866928441,0.032460916,DB0121210005483_,3.427718495,-0.675876612,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,ceftriaxone,DB01212
,47771,DB00512,10073508,197,4540,220,4878,0.726017647,0.962115126,0.786355826,1.176592505,0.839586169,DB0051210073508_,0.174846164,-0.038621161,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,vancomycin,DB00512
,47773,DB01137,10073508,80,7692,29,5564,0.001199904,1.995336913,1.287952162,3.17048027,0.006408508,DB0113710073508_,5.050128736,0.690812915,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,levofloxacin,DB01137
,47774,DB01212,10073508,97,1922,31,1910,7.60505567665305e-09,3.108779437,2.04423246,4.845686085,1.75349902158619e-07,DB0121210073508_,15.55648242,1.134230185,female,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,ceftriaxone,DB01212
,47777,DB00758,10013971,47,8253,53,10021,0.762717266,1.076751933,0.710469986,1.627423629,0.868575411,DB0075810013971_,0.140900868,0.07394904,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,47779,DB00758,10021097,191,8109,267,9807,0.140473511,0.865156253,0.712982431,1.048209973,0.270501555,DB0075810021097_,1.307477432,-0.144845149,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,clopidogrel,DB00758
,47780,DB00758,10050953,29,8271,57,10017,0.038537031,0.616190348,0.379469178,0.980919485,0.102722429,DB0075810050953_,2.275724796,-0.484199357,NA,10050953,Lower gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,47781,DB00068,10025482,69,2165,16,649,0.432236624,1.292636123,0.736146894,2.403527123,0.600680852,DB0006810025482_,0.509691513,0.256683639,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,47785,DB00635,10024670,42,33011,22,23772,0.254689362,1.374772791,0.802012045,2.418845438,0.415421029,DB0063510024670_,0.878462744,0.318288475,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,prednisone,DB00635
,47786,DB00635,10037153,308,32745,131,23663,2.30519780843656e-07,1.699021886,1.379524753,2.102230042,3.86060047115354e-06,DB0063510037153_,12.46468782,0.530052724,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,47787,DB00635,10037884,139,32914,66,23728,0.005547169,1.518265667,1.124209224,2.068330565,0.022230047,DB0063510037884_,3.806310434,0.417568675,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,47791,DB00005,10053459,167,127915,47,42372,0.343321295,1.176994562,0.84684288,1.663812651,0.512593026,DB0000510053459_,0.66827307,0.162964208,NA,10053459,Secretion discharge,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,47795,DB00413,10013709,142,2057,88,1119,0.354261137,0.877850642,0.661187297,1.170577054,0.524089151,DB0041310013709_,0.646093473,-0.130278812,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pramipexole,DB00413
,47796,DB01591,10013709,139,1816,46,610,1,1.01501076,0.71247944,1.467968513,1,DB0159110013709_,0,0.014899214,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,solifenacin,DB01591
,47797,DB06413,10013709,89,1467,36,638,0.764379049,1.075136451,0.713476327,1.649377018,0.869827189,DB0641310013709_,0.139460721,0.072447585,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,armodafinil,DB06413
,47799,DB00413,10053762,66,2133,47,1160,0.16313186,0.763766372,0.51367422,1.143171308,0.301562765,DB0041310053762_,1.19877711,-0.269493333,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,pramipexole,DB00413
,47800,DB01136,10053762,234,9650,216,10899,0.035670815,1.223533816,1.010452021,1.48215158,0.096820258,DB0113610053762_,2.334899029,0.201743242,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,47801,DB01591,10053762,155,1800,43,613,0.268627399,1.227476565,0.858660934,1.785759182,0.431066617,DB0159110053762_,0.841492637,0.204960489,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,solifenacin,DB01591
,47808,DB00043,10020751,149,6264,33,2267,0.010557586,1.634054404,1.110668893,2.468222788,0.03716932,DB0004310020751_,3.292271595,0.491064291,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,omalizumab,DB00043
,47813,DB00207,10000087,102,8978,42,5413,0.037990505,1.464193185,1.011021393,2.153968369,0.101600492,DB0020710000087_,2.286706905,0.381304364,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,47814,DB00281,10000087,98,11360,45,5626,0.721655462,1.078530378,0.749231995,1.573533694,0.836007033,DB0028110000087_,0.179118254,0.075599353,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,47815,DB00399,10000087,67,6925,34,4964,0.105627224,1.412522576,0.919911928,2.205275219,0.219592011,DB0039910000087_,1.515983951,0.345377167,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,47816,DB00586,10000087,83,7026,32,2773,1,1.023703822,0.671525294,1.595075464,1,DB0058610000087_,0,0.023427248,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,diclofenac,DB00586
,47817,DB00736,10003239,282,10309,91,5462,2.6487720056723e-05,1.641838605,1.28876423,2.108119307,0.000253881,DB0073610003239_,8.278644415,0.495816715,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,47818,DB00207,10008479,94,8986,75,5380,0.066419332,0.750414492,0.5470027,1.032468655,0.154922083,DB0020710008479_,1.86483298,-0.287129569,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,47819,DB00207,10008531,56,9024,27,5428,0.365496913,1.24751738,0.773836408,2.056946596,0.535124288,DB0020710008531_,0.625256245,0.22115548,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,47820,DB00281,10008531,123,11335,57,5614,0.750203716,1.068757049,0.773237908,1.492550475,0.858621644,DB0028110008531_,0.152426915,0.066496337,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,47821,DB00399,10008531,136,6856,46,4952,4.50981517940949e-06,2.135315366,1.514861924,3.058260919,5.40540319155396e-05,DB0039910008531_,9.825526421,0.758614348,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,47822,DB00586,10008531,57,7052,22,2783,1,1.022485132,0.613959502,1.760175059,1,DB0058610008531_,0,0.022236068,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,47823,DB00736,10008531,103,10488,40,5513,0.111711734,1.353523676,0.929469524,2.00510911,0.228642626,DB0073610008531_,1.475595081,0.302711323,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,47827,DB00316,10010741,50,65424,13,36940,0.011999845,2.171615602,1.16204019,4.358449466,0.04114627,DB0031610010741_,3.190621991,0.775471408,NA,10010741,Conjunctivitis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,47832,DB00281,10011224,194,11264,99,5572,0.802456882,0.969332305,0.755376518,1.250491742,0.893152549,DB0028110011224_,0.112997885,-0.03114779,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,47833,DB00736,10011224,274,10317,115,5438,0.045491135,1.255875952,1.003824483,1.57932298,0.116492228,DB0073610011224_,2.149930719,0.227833299,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,47834,DB01050,10011224,316,17792,131,9240,0.0306117,1.252783225,1.017052864,1.550132761,0.086051927,DB0105010011224_,2.452804362,0.225367656,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,47835,DB00207,10015090,36,9044,22,5433,1,0.98300689,0.562134395,1.755999969,1,DB0020710015090_,0,-0.017139149,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,47836,DB00281,10015090,53,11405,31,5640,0.485963471,0.845489269,0.532208732,1.364270666,0.649960453,DB0028110015090_,0.430843759,-0.167839802,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,47838,DB00736,10015090,70,10521,27,5526,0.198306498,1.361697466,0.860977878,2.211472656,0.347047924,DB0073610015090_,1.0582924,0.308732058,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,47839,DB00169,10015688,51,38640,7,18168,0.000628711,3.425394169,1.547496381,8.948723842,0.003745619,DB0016910015688_,5.587168479,1.231216551,female,10015688,Exostosis,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,47842,DB00316,10015688,50,65424,16,36937,0.053672848,1.764298401,0.987945579,3.319714761,0.13188736,DB0031610015688_,2.025807054,0.567753105,NA,10015688,Exostosis,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,47847,DB00169,10015958,106,38585,26,18149,0.001975371,1.917618739,1.238674307,3.070360942,0.009634034,DB0016910015958_,4.642453254,0.651084176,NA,10015958,Eye pain,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,47849,DB00316,10015958,128,65346,40,36913,0.000711352,1.807622252,1.258153382,2.647640382,0.004147715,DB0031610015958_,5.485197816,0.592012309,NA,10015958,Eye pain,10015919,Eye disorders,Eye,acetaminophen,DB00316
,47850,DB00635,10015958,67,32986,34,23760,0.106192383,1.419415904,0.925689106,2.213091633,0.220487917,DB0063510015958_,1.511912384,0.350245452,NA,10015958,Eye pain,10015919,Eye disorders,Eye,prednisone,DB00635
,47852,DB01050,10015958,43,18065,14,9357,0.161251015,1.590861071,0.853181805,3.150211706,0.299158875,DB0105010015958_,1.206780494,0.464275424,NA,10015958,Eye pain,10015919,Eye disorders,Eye,ibuprofen,DB01050
,47853,DB00207,10016256,415,8665,210,5245,0.038568422,1.196156238,1.007094635,1.424096554,0.10278543,DB0020710016256_,2.275111671,0.179113281,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,47854,DB00586,10016256,418,6691,135,2670,0.036768802,1.235508856,1.009711592,1.519463735,0.099119835,DB0058610016256_,2.311425708,0.211482914,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,47857,DB00316,10016750,78,65396,27,36926,0.032199744,1.631209699,1.040849402,2.629825413,0.089525097,DB0031610016750_,2.413236278,0.489321886,NA,10016750,Flank pain,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,47860,DB00635,10016750,48,33005,22,23772,0.089309014,1.571449625,0.930143797,2.734478204,0.194143608,DB0063510016750_,1.639157147,0.451998522,NA,10016750,Flank pain,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,47863,DB00169,10017577,722,37969,239,17936,1.40799106047454e-06,1.427034111,1.229763496,1.660635029,1.94733201918302e-05,DB0016910017577_,10.84646522,0.355598242,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,47864,DB00207,10017885,59,9021,32,5423,0.665772569,1.108384517,0.708004035,1.764072638,0.796678137,DB0020710017885_,0.227304525,0.102903565,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,47865,DB00281,10017885,45,11413,17,5654,0.417388235,1.311375228,0.735151716,2.446165314,0.586515354,DB0028110017885_,0.533556433,0.271076379,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,47866,DB00399,10017885,71,6921,25,4973,0.001709791,2.040521999,1.275285737,3.365283024,0.008547329,DB0039910017885_,4.762136436,0.713205657,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,47867,DB00586,10017885,83,7026,6,2799,6.34585118625695e-07,5.510468765,2.423189541,15.4670585,9.56560383145066e-06,DB0058610017885_,11.55733683,1.706649695,female,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,diclofenac,DB00586
,47868,DB00736,10017885,202,10389,91,5462,0.238568916,1.167017418,0.904705811,1.514983458,0.396295633,DB0073610017885_,0.925594797,0.154451278,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,47869,DB01050,10017885,125,17983,43,9328,0.02196422,1.507862898,1.057395932,2.18711214,0.06655479,DB0105010017885_,2.709729765,0.410693349,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,47870,DB00169,10018092,35,38656,20,18155,0.472815293,0.821917913,0.461377433,1.502988509,0.638788516,DB0016910018092_,0.44818184,-0.196114751,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,47874,DB00635,10018092,41,33012,30,23764,1,0.983803992,0.599267899,1.632203034,1,DB0063510018092_,0,-0.016328597,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,47877,DB00169,10021021,31,38660,19,18156,0.364990042,0.766217153,0.419246461,1.435985021,0.534590619,DB0016910021021_,0.626254024,-0.266289659,NA,10021021,Hypokinesia,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,47880,DB00316,10021021,46,65428,17,36936,0.149483978,1.527542557,0.859046093,2.842559397,0.28324256,DB0031610021021_,1.261451647,0.423660272,NA,10021021,Hypokinesia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,47886,DB00207,10022004,39,9041,23,5432,1,1.018778518,0.592806609,1.788772225,1,DB0020710022004_,0,0.018604378,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,47887,DB00281,10022004,78,11380,28,5643,0.148522205,1.381340971,0.885448108,2.212843526,0.28195191,DB0028110022004_,1.266018753,0.323054746,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,47888,DB00399,10022004,143,6849,33,4965,1.18683232220782e-10,3.141024511,2.134701437,4.745498349,3.81494232948242e-09,DB0039910022004_,19.38434029,1.144549024,female,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,47889,DB00586,10022004,41,7068,16,2789,1,1.011152325,0.554190476,1.933662429,1,DB0058610022004_,0,0.011090597,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,47890,DB00635,10022004,197,32856,78,23716,3.86278145534697e-06,1.823022724,1.394928349,2.402448829,4.71042498509836e-05,DB0063510022004_,9.963147331,0.600495961,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,47891,DB00736,10022004,71,10520,26,5527,0.13309072,1.434661905,0.902658444,2.345985058,0.260056966,DB0073610022004_,1.346854571,0.360929215,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,47892,DB01050,10022004,131,17977,47,9324,0.031986043,1.445616121,1.027472786,2.064886482,0.089081707,DB0105010022004_,2.418201279,0.368535612,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,47902,DB00169,10025482,1281,37410,369,17806,2.35615686821525e-18,1.652334005,1.468468391,1.862746773,2.09228321895398e-16,DB0016910025482_,36.10310557,0.502188837,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,47903,DB00207,10025482,231,8849,118,5337,0.161764175,1.180710947,0.939182517,1.490576526,0.299758582,DB0020710025482_,1.204777856,0.166116754,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,47904,DB00281,10025482,261,11197,88,5583,0.001535411,1.478817214,1.154497328,1.909225322,0.00784341,DB0028110025482_,4.848081593,0.391242589,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,47905,DB00399,10025482,230,6762,90,4908,4.88975312060643e-07,1.854774569,1.443291586,2.400645196,7.60515744231598e-06,DB0039910025482_,11.78668393,0.617763162,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,47906,DB00635,10025482,1075,31978,389,23405,7.78234549291979e-35,2.022586847,1.797135275,2.28007196,2.35125231357927e-32,DB0063510025482_,72.82777489,0.70437731,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,47907,DB00207,10028411,57,9023,28,5427,0.432175677,1.224351327,0.764902137,2.002057345,0.600631189,DB0020710028411_,0.509774196,0.202411174,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,azithromycin,DB00207
,47908,DB00281,10028411,97,11361,27,5644,0.00709317,1.784699834,1.153325238,2.848279572,0.02707187,DB0028110028411_,3.609260087,0.579250241,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lidocaine,DB00281
,47909,DB00316,10028411,635,64839,279,36674,0.000412938,1.287347539,1.115857216,1.488182182,0.002631293,DB0031610028411_,5.94028008,0.252583931,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,47910,DB00399,10028411,183,6809,66,4932,6.53661298013467e-07,2.008261127,1.503942793,2.709750945,9.81799269616228e-06,DB0039910028411_,11.53129387,0.697269237,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,47911,DB00586,10028411,83,7026,26,2779,0.336633126,1.262608618,0.802265,2.048735887,0.505667832,DB0058610028411_,0.681875284,0.233179912,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,47912,DB00635,10028411,347,32706,179,23615,0.000264498,1.399697064,1.164398073,1.687290161,0.001820698,DB0063510028411_,6.308535188,0.33625583,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,47913,DB00736,10028411,122,10469,46,5507,0.060158045,1.395093712,0.984551845,2.006678536,0.143758922,DB0073610028411_,1.939617538,0.33296159,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,47923,DB00586,10028813,444,6665,121,2684,0.000141812,1.477634843,1.199572345,1.831096842,0.001075265,DB0058610028813_,6.835187697,0.390442731,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,diclofenac,DB00586
,47924,DB00169,10033546,34,38657,19,18156,0.556943109,0.840477161,0.465868423,1.560253559,0.710195904,DB0016910033546_,0.342214425,-0.173785499,NA,10033546,Pallor,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,47927,DB00316,10033546,69,65405,44,36909,0.556779578,0.884952719,0.597543698,1.322901982,0.710089821,DB0031610033546_,0.342363808,-0.12222106,NA,10033546,Pallor,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,47933,DB00207,10033557,56,9024,12,5443,0.000587214,2.814608005,1.489639759,5.774060008,0.003531617,DB0020710033557_,5.645999415,1.034823,female,10033557,Palpitations,10007541,Cardiac disorders,Card,azithromycin,DB00207
,47934,DB00281,10033557,67,11391,11,5660,0.000239138,3.026315529,1.586204131,6.356017488,0.001672411,DB0028110033557_,6.393489237,1.107345883,female,10033557,Palpitations,10007541,Cardiac disorders,Card,lidocaine,DB00281
,47937,DB00736,10033557,89,10502,19,5534,0.000145276,2.468214127,1.489890657,4.295663145,0.001097295,DB0073610033557_,6.814907095,0.903494863,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,esomeprazole,DB00736
,47938,DB01050,10033557,147,17961,18,9353,8.08643791370169e-12,4.252184891,2.59685522,7.37979109,3.13498555400662e-10,DB0105010033557_,21.88322636,1.447432943,female,10033557,Palpitations,10007541,Cardiac disorders,Card,ibuprofen,DB01050
,47942,DB00316,10034263,111,65363,11,36942,8.76977250754813e-12,5.703898294,3.066675784,11.75819428,3.38244270522234e-10,DB0031610034263_,21.80725279,1.741149852,female,10034263,Pelvic pain,10038604,Reproductive system and breast disorders,Repro,acetaminophen,DB00316
,47947,DB00399,10037660,265,6727,144,4854,0.006822615,1.32785708,1.076141452,1.64378229,0.026260424,DB0039910037660_,3.639692247,0.283566425,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,47948,DB00586,10037660,120,6989,50,2755,0.731809031,0.946060202,0.672649596,1.347672163,0.844114034,DB0058610037660_,0.169467683,-0.055449073,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,47967,DB00281,10046735,130,11328,45,5626,0.036015268,1.434725227,1.013287719,2.06444097,0.097563775,DB0028110046735_,2.327249011,0.360973351,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,lidocaine,DB00281
,47968,DB00399,10046735,43,6949,27,4971,0.62863984,1.139220285,0.687058874,1.920102052,0.76784714,DB0039910046735_,0.264164602,0.130344068,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,zoledronic acid,DB00399
,47969,DB00635,10046735,430,32623,149,23645,4.86905458267567e-16,2.091649008,1.730749257,2.539290231,3.38132363819366e-14,DB0063510046735_,31.01792406,0.737952754,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,47970,DB00736,10046735,109,10482,39,5514,0.045149836,1.470194341,1.009657009,2.180719161,0.115867381,DB0073610046735_,2.155309008,0.385394597,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,esomeprazole,DB00736
,47971,DB01050,10046735,222,17886,89,9282,0.040847649,1.294490267,1.006473713,1.676759013,0.107335844,DB0105010046735_,2.231792633,0.258117001,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,47981,DB00207,10047513,41,9039,29,5426,0.536674684,0.84869827,0.51411097,1.417834638,0.692968223,DB0020710047513_,0.366771135,-0.16405155,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,azithromycin,DB00207
,47982,DB00399,10047513,70,6922,31,4967,0.025642883,1.620247473,1.045556135,2.563431125,0.074922731,DB0039910047513_,2.591297951,0.482578899,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,zoledronic acid,DB00399
,47983,DB00635,10047513,228,32825,124,23670,0.012566731,1.325880149,1.060103214,1.664749954,0.042717947,DB0063510047513_,3.153136138,0.282076502,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,prednisone,DB00635
,47984,DB00736,10047513,98,10493,39,5514,0.14925327,1.320468944,0.900996718,1.96907906,0.282960856,DB0073610047513_,1.262446708,0.277986934,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,esomeprazole,DB00736
,47985,DB00281,10047895,142,11316,78,5593,0.471105997,0.899808581,0.67654462,1.204164948,0.637396532,DB0028110047895_,0.450363317,-0.105573226,NA,10047895,Weight decreased,10022891,Investigations,Inv,lidocaine,DB00281
,47986,DB00207,10047899,101,8979,48,5407,0.202017457,1.267044025,0.888472285,1.829104428,0.351401552,DB0020710047899_,1.045825686,0.236686648,NA,10047899,Weight increased,10022891,Investigations,Inv,azithromycin,DB00207
,47987,DB00281,10047899,110,11348,48,5623,0.497596503,1.135518155,0.800678529,1.631493216,0.659693569,DB0028110047899_,0.415979842,0.127089071,NA,10047899,Weight increased,10022891,Investigations,Inv,lidocaine,DB00281
,47988,DB00399,10047899,122,6870,61,4937,0.023202778,1.437220032,1.046038897,1.992354259,0.069360289,DB0039910047899_,2.668440783,0.362710714,NA,10047899,Weight increased,10022891,Investigations,Inv,zoledronic acid,DB00399
,47989,DB00586,10047899,122,6987,28,2777,0.007883847,1.731676716,1.137749839,2.719698716,0.029433553,DB0058610047899_,3.525619999,0.549090139,NA,10047899,Weight increased,10022891,Investigations,Inv,diclofenac,DB00586
,47990,DB01050,10047899,261,17847,72,9299,6.63039044290935e-07,1.888729873,1.447970928,2.490237941,9.95031760159134e-06,DB0105010047899_,11.51790609,0.635904578,NA,10047899,Weight increased,10022891,Investigations,Inv,ibuprofen,DB01050
,47991,DB00207,10047924,61,9019,28,5427,0.272344265,1.310887477,0.823974937,2.132990054,0.435290445,DB0020710047924_,0.831741781,0.270704371,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,47992,DB00281,10047924,39,11419,28,5643,0.151883887,0.688313781,0.412384534,1.162747046,0.286564114,DB0028110047924_,1.249792983,-0.373510468,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,47994,DB00736,10047924,74,10517,17,5536,0.001225342,2.291224711,1.337474083,4.146018686,0.006504717,DB0073610047924_,5.035227648,0.829086483,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,47995,DB01050,10047924,58,18050,24,9347,0.414442006,1.251391684,0.764883063,2.107504794,0.583669531,DB0105010047924_,0.538420328,0.224256279,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,47996,DB00169,10061246,69,38622,20,18155,0.067936802,1.621724921,0.973691164,2.818124866,0.157588691,DB0016910061246_,1.847766859,0.483490349,NA,10061246,Intervertebral disc degeneration,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,47999,DB00316,10061246,88,65386,47,36906,0.788615709,1.056813914,0.733321483,1.540020592,0.885530673,DB0031610061246_,0.121568183,0.05525864,NA,10061246,Intervertebral disc degeneration,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,48001,DB00635,10061246,47,33006,22,23772,0.111939912,1.538665414,0.908760617,2.681720566,0.228992618,DB0063510061246_,1.474065513,0.430915426,NA,10061246,Intervertebral disc degeneration,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,48012,DB00169,10061623,258,38433,144,18031,0.096419732,0.840584305,0.682346946,1.038769609,0.205396926,DB0016910061623_,1.58281095,-0.173658028,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,48013,DB00281,10061623,55,11403,20,5651,0.269092822,1.362820783,0.802927647,2.403071541,0.431602687,DB0028110061623_,0.84024982,0.309556657,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,48014,DB00316,10061623,344,65130,221,36732,0.13536921,0.877874314,0.73885175,1.04478304,0.263217909,DB0031610061623_,1.334773039,-0.130251846,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,48015,DB00399,10061623,70,6922,52,4946,0.853834813,0.961852435,0.660985241,1.407516846,0.9288062,DB0039910061623_,0.073855173,-0.038894234,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,48017,DB00635,10061623,176,32877,112,23682,0.338058372,1.131892807,0.887547031,1.448517324,0.507155089,DB0063510061623_,0.678938427,0.123891282,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,48018,DB00736,10061623,52,10539,25,5528,0.81021783,1.091009267,0.664073485,1.836875105,0.897850953,DB0073610061623_,0.107751201,0.0871032,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,48019,DB01050,10061623,101,18007,36,9335,0.057565703,1.45440797,0.984295923,2.193049491,0.13887238,DB0105010061623_,1.974199896,0.374598925,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,48044,DB00073,10036807,93,7313,52,6355,0.011825723,1.554120752,1.093266211,2.229995126,0.040699068,DB0007310036807_,3.201550074,0.440909953,NA,10036807,Progressive multifocal leukoencephalopathy,10021881,Infections and infestations,Infec,rituximab,DB00073
,48052,DB00374,10047513,92,17624,35,5689,0.408046764,0.848534818,0.568430098,1.292292758,0.577463009,DB0037410047513_,0.549110892,-0.16424416,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,treprostinil,DB00374
,48054,DB00381,10006002,136,29224,50,22837,2.49693492026482e-06,2.125478043,1.525710325,3.002927268,3.21567537379524e-05,DB0038110006002_,10.34488806,0.753996739,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,48056,DB00451,10006002,255,47016,32,15387,1.25564432521906e-08,2.608039392,1.8004652,3.895482713,2.76304822841215e-07,DB0045110006002_,15.10176115,0.958598748,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,48058,DB01076,10006002,93,25654,50,25533,0.000402418,1.851194385,1.298430473,2.666732564,0.002575806,DB0107610006002_,5.96159287,0.615831044,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,48060,DB00394,10016256,96,1543,31,763,0.041679029,1.531078513,1.001302342,2.398255872,0.109078836,DB0039410016256_,2.215684394,0.425972397,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,beclomethasone dipropionate,DB00394
,48063,DB00811,10016322,30,2768,40,4116,0.713550656,1.115226014,0.669020341,1.841007892,0.830069995,DB0081110016322_,0.186245251,0.109057088,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,48064,DB01050,10016322,292,17816,113,9258,0.008211317,1.342795567,1.075453034,1.686124903,0.030422787,DB0105010016322_,3.492563367,0.294753685,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,48065,DB01076,10016322,404,25343,266,25317,1.38670319239567e-07,1.517218092,1.295145239,1.779644506,2.44545410346328e-06,DB0107610016322_,12.92127972,0.416878455,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,48066,DB08934,10016322,34,4455,54,6150,0.588019707,0.869219298,0.547689284,1.362202267,0.735024633,DB0893410016322_,0.307851266,-0.140159829,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,48067,DB00394,10025482,45,1594,10,784,0.019866837,2.212685011,1.091985757,4.951340225,0.061424433,DB0039410025482_,2.789947595,0.794206715,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,beclomethasone dipropionate,DB00394
,48068,DB08934,10025482,52,4437,50,6154,0.069690073,1.44237643,0.957337435,2.175115572,0.160747976,DB0893410025482_,1.827917507,0.366292052,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,48073,DB00451,10033318,193,47078,47,15372,0.071746318,1.340802371,0.969829145,1.886908481,0.16431576,DB0045110033318_,1.805965337,0.293268219,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,48074,DB00641,10033318,65,14059,28,12447,0.001162739,2.055145994,1.299804277,3.327327285,0.00624186,DB0064110033318_,5.076477056,0.720346889,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,simvastatin,DB00641
,48075,DB06228,10033318,112,15800,52,16024,2.04317754348382e-06,2.184319172,1.557380795,3.098719682,2.70009661792218e-05,DB0622810033318_,10.51963791,0.781304188,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,rivaroxaban,DB06228
,48076,DB00203,10059570,54,13824,23,8915,0.102049415,1.514069403,0.912878446,2.586843941,0.214034688,DB0020310059570_,1.541617182,0.414800995,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,sildenafil,DB00203
,48080,DB00451,10059570,73,47198,24,15395,1,0.992128018,0.617855353,1.646401395,1,DB0045110059570_,0,-0.00790313,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,levothyroxine,DB00451
,48081,DB00559,10059570,54,9605,15,3291,0.579618256,1.233455574,0.684906597,2.356804029,0.728280593,DB0055910059570_,0.317068875,0.20981964,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,bosentan,DB00559
,48083,DB00695,10059570,69,27980,45,20483,0.570271148,1.122524065,0.75968515,1.673138479,0.720895356,DB0069510059570_,0.32726129,0.115579779,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,furosemide,DB00695
,48085,DB00421,10061818,115,8788,72,5180,0.703526762,0.941471455,0.69374343,1.28484164,0.822204479,DB0042110061818_,0.195766157,-0.06031125,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,48086,DB00641,10061818,124,14000,148,12327,0.014442618,0.737729349,0.575610465,0.944159114,0.047793555,DB0064110061818_,3.04086449,-0.304178257,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,48087,DB00390,10064911,117,4028,39,3262,5.17892332548189e-07,2.429164469,1.672109128,3.596703498,7.99811983609233e-06,DB0039010064911_,11.73630406,0.887547358,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,48088,DB00641,10064911,50,14074,10,12465,1.4813643278099e-06,4.42806614,2.218219701,9.798447565,2.0359561493586e-05,DB0064110064911_,10.8019599,1.487962952,female,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,48089,DB06228,10064911,118,15794,49,16027,5.60787024695101e-08,2.443733488,1.735852144,3.485721228,1.0720208686626e-06,DB0622810064911_,13.74596503,0.893526988,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,48091,DB01080,10021750,50,2009,57,2055,0.624750747,0.897301675,0.598086779,1.342521321,0.764469688,DB0108010021750_,0.268572903,-0.108363158,NA,10021750,Infantile spasms,10029205,Nervous system disorders,Nerv,vigabatrin,DB01080
,48097,DB00537,10043607,35,7522,20,4278,1,0.995280328,0.558091527,1.821957588,1,DB0053710043607_,0,-0.004730845,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,ciprofloxacin,DB00537
,48099,DB00761,10043607,163,15144,99,8526,0.560738911,0.926955827,0.716634391,1.20405328,0.713322312,DB0076110043607_,0.33782191,-0.075849366,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,potassium chloride,DB00761
,48106,DB00695,10064687,98,27951,42,20486,0.003447303,1.710135476,1.179286632,2.518011886,0.015136114,DB0069510064687_,4.190671734,0.536572593,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,48107,DB00761,10064687,47,15260,27,8598,1,0.980783519,0.597934898,1.638974366,1,DB0076110064687_,0,-0.019403517,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,48111,DB01234,10064687,33,31592,41,32847,0.486060248,0.836855255,0.51252329,1.356892525,0.649960453,DB0123410064687_,0.430843759,-0.178104156,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,48114,DB08904,10013968,140,11470,30,3529,0.083206627,1.435749169,0.960422255,2.211193869,0.183804202,DB0890410013968_,1.693884208,0.361686782,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,certolizumab pegol,DB08904
,48117,DB00512,10034133,27,4710,35,5063,0.524490827,0.829261364,0.48194228,1.412560178,0.682639271,DB0051210034133_,0.381788713,-0.187219898,NA,10034133,Pathogen resistance,10021881,Infections and infestations,Infec,vancomycin,DB00512
,48121,DB00921,10022437,102,5743,101,4802,0.255041026,0.844442488,0.633194571,1.126261406,0.415741791,DB0092110022437_,0.877690905,-0.169078647,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,48122,DB00921,10028334,65,5780,26,4877,0.000981776,2.109244799,1.317312192,3.469629118,0.005421997,DB0092110028334_,5.217291077,0.746329968,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,buprenorphine,DB00921
,48123,DB00921,10041349,102,5743,111,4792,0.060503171,0.766776402,0.578560469,1.015377236,0.14431269,DB0092110041349_,1.935772873,-0.265560043,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,buprenorphine,DB00921
,48124,DB00921,10042458,31,5814,32,4871,0.4474549,0.8116428,0.478246583,1.375790619,0.615213916,DB0092110042458_,0.48578524,-0.208694938,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,48128,DB00531,10061188,41,7211,43,6473,0.51157557,0.855915885,0.543379074,1.346420467,0.671901457,DB0053110061188_,0.39764359,-0.155583173,NA,10061188,Haematotoxicity,10005329,Blood and lymphatic system disorders,Blood,cyclophosphamide,DB00531
,48129,DB00541,10061188,36,3098,43,4254,0.5677679,1.149584224,0.715441359,1.837505069,0.718825433,DB0054110061188_,0.330136742,0.139400332,NA,10061188,Haematotoxicity,10005329,Blood and lymphatic system disorders,Blood,vincristine,DB00541
,48130,DB00773,10061188,38,2285,46,2781,1,1.005403175,0.634183013,1.585566976,1,DB0077310061188_,0,0.00538863,NA,10061188,Haematotoxicity,10005329,Blood and lymphatic system disorders,Blood,etoposide,DB00773
,48133,DB00563,10027175,257,46389,69,15279,0.139091441,1.226762003,0.936480711,1.625519153,0.268540843,DB0056310027175_,1.314752262,0.204378181,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,48135,DB00811,10003239,77,2721,68,4088,0.001961294,1.701047657,1.206979539,2.401884924,0.009582272,DB0081110003239_,4.647840594,0.53124433,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ribavirin,DB00811
,48136,DB05351,10003239,86,2637,20,1111,0.016934397,1.811397101,1.097122172,3.12828131,0.054239105,DB0535110003239_,2.914353134,0.594098427,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,dexlansoprazole,DB05351
,48137,DB14513,10003239,233,6944,65,3499,1.52561323210027e-05,1.806155725,1.362107465,2.423448926,0.000157289,DB1451310003239_,8.757427844,0.591200678,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,48144,DB00811,10012174,34,2764,46,4110,0.731120304,1.099052369,0.682222134,1.754917761,0.843600616,DB0081110012174_,0.1700761,0.094448326,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ribavirin,DB00811
,48146,DB05351,10012378,59,2664,18,1113,0.311443409,1.369384732,0.792115753,2.478736132,0.478940472,DB0535110012378_,0.736178966,0.314361538,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,dexlansoprazole,DB05351
,48153,DB05351,10020772,39,2684,15,1116,0.881086225,1.081050445,0.579873767,2.119963729,0.950229659,DB0535110020772_,0.051051578,0.077933202,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,dexlansoprazole,DB05351
,48154,DB14513,10020772,103,7074,42,3522,0.288306982,1.220939037,0.842930439,1.79656454,0.453304061,DB1451310020772_,0.791192161,0.199620265,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,magnesium,DB14513
,48156,DB14513,10028411,108,7069,31,3533,0.006311075,1.741114954,1.155805416,2.692307168,0.024659819,DB1451310028411_,3.702580112,0.554525686,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,48158,DB00404,10033433,78,19814,12,9850,2.52171226201586e-05,3.231199855,1.747848626,6.523286378,0.00024333,DB0040410033433_,8.321090279,1.17285354,female,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,48160,DB14513,10033433,47,7130,12,3552,0.03734348,1.951085326,1.017474972,4.046233605,0.100267977,DB1451310033433_,2.299908906,0.668385795,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,48167,DB00404,10048959,325,19567,104,9758,6.60529682627695e-05,1.558405797,1.244184733,1.965469211,0.000558354,DB0040410048959_,7.490517096,0.443663374,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,48168,DB00811,10048959,33,2765,33,4123,0.129499631,1.491013947,0.889664187,2.498969474,0.25492588,DB0081110048959_,1.366782445,0.39945639,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,48169,DB05351,10048959,44,2679,7,1124,0.01267707,2.636686671,1.173457569,6.959918014,0.043008459,DB0535110048959_,3.146358454,0.96952308,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,dexlansoprazole,DB05351
,48170,DB14513,10048959,161,7016,60,3504,0.060317544,1.340121963,0.987450661,1.839247244,0.144046394,DB1451310048959_,1.937619852,0.292760627,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,48175,DB00404,10068319,141,19751,36,9826,0.000210414,1.948478315,1.341853762,2.89594442,0.001503526,DB0040410068319_,6.499941939,0.667048717,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,48178,DB14513,10068319,71,7106,18,3546,0.008998562,1.9682275,1.158416777,3.514549522,0.032716872,DB1451310068319_,3.419864367,0.677133391,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium,DB14513
,48184,DB00005,10018852,45,128037,27,42392,0.019497831,0.551833149,0.335039833,0.925003595,0.060618665,DB0000510018852_,2.803152438,-0.594509545,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,etanercept,DB00005
,48187,DB00213,10043882,46,18849,14,13407,0.003761688,2.337002192,1.261755373,4.604845005,0.016233127,DB0021310043882_,4.120701228,0.848868994,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,pantoprazole,DB00213
,48188,DB08910,10037423,36,16708,48,17440,0.276455962,0.782865709,0.493383176,1.232241152,0.439896178,DB0891010037423_,0.821216539,-0.244794106,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,48189,DB00295,10002198,98,14565,34,9568,0.000929223,1.893416385,1.268752366,2.888042335,0.005184046,DB0029510002198_,5.262169377,0.638382808,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,morphine,DB00295
,48190,DB00537,10002198,43,7514,21,4277,0.604422181,1.165526446,0.675602031,2.07047467,0.74779372,DB0053710002198_,0.290628115,0.15317287,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,ciprofloxacin,DB00537
,48191,DB01190,10002198,51,4883,11,2274,0.019058055,2.158947085,1.108498569,4.602959237,0.059490644,DB0119010002198_,2.821936216,0.769620642,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,clindamycin,DB01190
,48192,DB00480,10012267,104,67324,99,67563,0.725807605,1.05425425,0.792662045,1.402848995,0.839398667,DB0048010012267_,0.175069516,0.052833645,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,48194,DB00480,10061818,108,67320,135,67527,0.094956077,0.802462815,0.617054317,1.041481193,0.203143326,DB0048010061818_,1.593843508,-0.220069762,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,48195,DB00257,10003549,32,920,21,601,1,0.995447606,0.550644665,1.834963961,1,DB0025710003549_,0,-0.004562788,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,clotrimazole,DB00257
,48196,DB00465,10003549,43,2061,21,862,0.580496115,0.85646342,0.493790043,1.528937178,0.728979664,DB0046510003549_,0.316109443,-0.154943671,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ketorolac,DB00465
,48197,DB00715,10003549,121,4722,65,2222,0.426050646,0.8759956,0.639854103,1.208396644,0.594773566,DB0071510003549_,0.519574506,-0.132394211,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,48198,DB00727,10003549,143,3700,145,4028,0.588875983,1.073598752,0.84238247,1.368225624,0.73565767,DB0072710003549_,0.30699039,0.071016324,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,48199,DB00758,10003549,278,8022,362,9712,0.374120645,0.929724184,0.790064028,1.093180808,0.543950913,DB0075810003549_,0.608896269,-0.072867313,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,48201,DB00959,10003549,204,7874,136,4866,0.498019692,0.926981098,0.740217248,1.163757995,0.660081963,DB0095910003549_,0.415391266,-0.075822104,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,48202,DB00973,10003549,105,3746,102,2919,0.118464542,0.802180363,0.602248091,1.068767371,0.238892208,DB0097310003549_,1.43174284,-0.220421805,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,48205,DB00654,10003988,49,3767,22,2576,0.11406775,1.522986624,0.901050995,2.652151059,0.23226205,DB0065410003988_,1.459889019,0.420673291,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,latanoprost,DB00654
,48206,DB00715,10003988,82,4761,35,2252,0.689747928,1.108175127,0.734879862,1.70228874,0.812888491,DB0071510003988_,0.207161336,0.102714632,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,paroxetine,DB00715
,48207,DB00727,10003988,94,3749,81,4092,0.126487892,1.26662673,0.927705316,1.732623523,0.250790847,DB0072710003988_,1.383135968,0.236357248,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,nitroglycerin,DB00727
,48209,DB00973,10003988,111,3740,57,2964,0.009218382,1.543218221,1.107105629,2.171122735,0.03335491,DB0097310003988_,3.400550278,0.43386999,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ezetimibe,DB00973
,48211,DB00455,10010305,98,9303,57,5061,0.735386881,0.9353345,0.666751555,1.32273837,0.847122629,DB0045510010305_,0.165909814,-0.066851059,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,loratadine,DB00455
,48213,DB00641,10010305,178,13946,189,12286,0.082109776,0.829704016,0.67130512,1.025174271,0.181856119,DB0064110010305_,1.704539458,-0.186686249,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,48214,DB00654,10010305,19,3797,33,2565,0.000954225,0.389000076,0.208490562,0.706238419,0.005301023,DB0065410010305_,5.239855405,-0.94417574,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,latanoprost,DB00654
,48215,DB00715,10010305,92,4751,59,2228,0.06466352,0.731262109,0.519529951,1.036173579,0.151858889,DB0071510010305_,1.884803554,-0.312983321,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,paroxetine,DB00715
,48218,DB00959,10010305,59,8019,47,4955,0.193864553,0.775699313,0.518889101,1.165265221,0.341536848,DB0095910010305_,1.074299705,-0.253990317,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,methylprednisolone,DB00959
,48220,DB13961,10010305,71,9386,66,6348,0.066525806,0.727591315,0.512185859,1.034785368,0.155089207,DB1396110010305_,1.863754802,-0.318015768,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,fish oil,DB13961
,48222,DB00455,10011906,220,9181,234,4884,5.93111852533905e-13,0.500153572,0.412786716,0.605890484,2.73028809874846e-11,DB0045510011906_,24.32402889,-0.692840083,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,48224,DB00641,10011906,453,13671,661,11814,2.34871315922983e-17,0.59225339,0.523017123,0.670224091,1.8908399813279e-15,DB0064110011906_,33.90175523,-0.523820712,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,48225,DB00654,10011906,108,3708,125,2473,4.17085047719435e-05,0.576302057,0.438982991,0.755575223,0.000378102,DB0065410011906_,7.880345373,-0.551123351,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,48226,DB00715,10011906,168,4675,141,2146,3.83020678306062e-07,0.546961486,0.432029411,0.693297486,6.08136425809413e-06,DB0071510011906_,12.0102815,-0.603376888,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,48227,DB00727,10011906,169,3674,250,3923,0.001528536,0.72184665,0.587170763,0.88571664,0.007812088,DB0072710011906_,4.852082964,-0.325942559,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,48228,DB00804,10011906,57,2943,58,841,1.06436377519107e-10,0.280972961,0.189837879,0.41565495,3.44966730343986e-09,DB0080410011906_,19.48498804,-1.269496838,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dicyclomine,DB00804
,48230,DB00973,10011906,82,3769,122,2899,5.46205037185125e-06,0.517042125,0.384256395,0.692711781,6.38798638594483e-05,DB0097310011906_,9.658506366,-0.659630928,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,48232,DB00257,10013573,36,916,21,601,0.78283559,1.124714278,0.63204864,2.048777575,0.881806742,DB0025710013573_,0.12578236,0.117529028,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,clotrimazole,DB00257
,48233,DB00465,10013573,54,2050,24,859,0.80233388,0.942824852,0.568647208,1.605760828,0.893104952,DB0046510013573_,0.113051177,-0.058874748,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ketorolac,DB00465
,48234,DB00727,10013573,159,3684,161,4012,0.530416093,1.075473184,0.854306128,1.353865967,0.687463942,DB0072710013573_,0.374745899,0.072760735,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,48236,DB00959,10013573,246,7832,105,4897,0.001010798,1.464842598,1.15756386,1.864255137,0.005553477,DB0095910013573_,5.193331096,0.381747795,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,48237,DB00973,10013573,158,3693,99,2922,0.083566781,1.262722342,0.971211751,1.648197901,0.184406064,DB0097310013573_,1.690615081,0.233269979,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ezetimibe,DB00973
,48238,DB00257,10016173,34,918,16,606,0.305285374,1.40248703,0.745608532,2.746334235,0.472108375,DB0025710016173_,0.750546712,0.33824711,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,clotrimazole,DB00257
,48240,DB00654,10016173,91,3725,74,2524,0.261120377,0.833274226,0.603683159,1.153290565,0.42265836,DB0065410016173_,0.861191085,-0.182392488,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,latanoprost,DB00654
,48241,DB00715,10016173,177,4666,68,2219,0.144189483,1.237804668,0.926203373,1.670148801,0.275828431,DB0071510016173_,1.287976234,0.213339382,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,paroxetine,DB00715
,48242,DB00727,10016173,155,3688,128,4045,0.021228066,1.32810271,1.039483762,1.699259191,0.064817299,DB0072710016173_,2.736182754,0.28375139,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,nitroglycerin,DB00727
,48244,DB00959,10016173,163,7915,90,4912,0.396260337,1.123978925,0.861354236,1.474367956,0.565947781,DB0095910016173_,0.569253465,0.116875001,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,methylprednisolone,DB00959
,48246,DB00186,10019063,133,16768,111,9897,0.007743471,0.707246338,0.544822471,0.919460801,0.029027414,DB0018610019063_,3.539514579,-0.346376246,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,48249,DB00338,10019063,145,33529,163,22109,3.56123800372807e-06,0.586606565,0.465409416,0.73872718,4.39263918010287e-05,DB0033810019063_,10.03299524,-0.53340093,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,48251,DB00641,10019063,60,14064,113,12362,1.16846146421717e-06,0.466725982,0.335068289,0.644517547,1.64372542611444e-05,DB0064110019063_,11.0159602,-0.762012957,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,48252,DB00654,10019063,20,3796,34,2564,0.001152515,0.397378596,0.216242874,0.712283696,0.006196327,DB0065410019063_,5.083798514,-0.92286581,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,latanoprost,DB00654
,48253,DB00695,10019063,111,27938,107,20421,0.046093453,0.758277388,0.575807141,0.998971414,0.117667791,DB0069510019063_,2.139889955,-0.276706013,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,48254,DB00715,10019063,34,4809,20,2267,0.464868979,0.801441471,0.447155999,1.472848188,0.631757386,DB0071510019063_,0.459249842,-0.221343334,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,paroxetine,DB00715
,48255,DB00722,10019063,117,25286,125,25907,0.747856118,0.958976843,0.738373223,1.244804155,0.856755494,DB0072210019063_,0.154602705,-0.041888352,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,48256,DB00727,10019063,26,3817,31,4142,0.790725944,0.910153097,0.518006929,1.587212169,0.88663055,DB0072710019063_,0.1203269,-0.094142455,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,nitroglycerin,DB00727
,48257,DB00788,10019063,43,9313,43,5018,0.004508985,0.538820859,0.344247892,0.843426396,0.018802945,DB0078810019063_,3.973741771,-0.618372121,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,naproxen,DB00788
,48263,DB13961,10019063,28,9429,41,6373,0.001892386,0.461603431,0.274589364,0.765612702,0.009294845,DB1396110019063_,4.678295353,-0.773049132,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,fish oil,DB13961
,48265,DB00316,10036653,113,65361,74,36879,0.322523464,0.861610056,0.636886706,1.171559136,0.49085341,DB0031610036653_,0.711609749,-0.148952482,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,48266,DB00381,10036653,68,29292,58,22829,0.653373985,0.913734068,0.633894654,1.320850851,0.787503919,DB0038110036653_,0.238886932,-0.090215704,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,48271,DB00695,10036653,127,27922,58,20470,0.002766769,1.605247382,1.167066937,2.230656549,0.012650953,DB0069510036653_,4.370022769,0.473277877,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,48272,DB00722,10036653,49,25354,48,25984,0.839574121,1.046214097,0.687855416,1.591957155,0.917802954,DB0072210036653_,0.085772558,0.045178027,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,48274,DB00758,10036653,26,8274,31,10043,1,1.018030591,0.580097398,1.773416061,1,DB0075810036653_,0,0.017869968,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,48282,DB00381,10044565,283,29077,164,22723,0.00252442,1.348514771,1.10774593,1.646088571,0.011746218,DB0038110044565_,4.444224,0.299003817,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,48283,DB00455,10044565,98,9303,44,5074,0.331534672,1.214736752,0.841433558,1.778533978,0.50033811,DB0045510044565_,0.69247119,0.194527388,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,48285,DB00641,10044565,149,13975,110,12365,0.168591196,1.198484976,0.929311453,1.549540036,0.309014301,DB0064110044565_,1.174367721,0.181058239,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,48286,DB00654,10044565,43,3773,22,2576,0.310447939,1.334398854,0.778600783,2.348246709,0.477865171,DB0065410044565_,0.738426655,0.288480894,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,latanoprost,DB00654
,48287,DB00695,10044565,287,27762,159,20369,0.004474147,1.324344374,1.086319259,1.619290915,0.018689214,DB0069510044565_,3.97980869,0.280917525,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,48288,DB00727,10044565,44,3799,35,4138,0.175581243,1.36926142,0.85645411,2.204128887,0.318098159,DB0072710044565_,1.145395268,0.314271485,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,48289,DB00758,10044565,74,8226,100,9974,0.49205398,0.897276051,0.654214589,1.225894454,0.65501299,DB0075810044565_,0.423100211,-0.108391715,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,48290,DB00788,10044565,103,9253,41,5020,0.096161047,1.362905128,0.938738515,2.011520102,0.204978762,DB0078810044565_,1.584848903,0.309618545,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,48293,DB00959,10044565,89,7989,41,4961,0.123340081,1.34794869,0.919435903,2.005549019,0.246155729,DB0095910044565_,1.401790898,0.298583948,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,48294,DB00973,10044565,37,3814,28,2993,0.900935978,1.036978187,0.616049381,1.763598551,0.956813906,DB0097310044565_,0.044146362,0.036310894,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,ezetimibe,DB00973
,48296,DB00811,10035664,45,2753,61,4095,0.689926398,1.097296554,0.727176087,1.644978848,0.812974205,DB0081110035664_,0.207055898,0.092849477,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ribavirin,DB00811
,48309,DB00175,10007739,35,8096,20,6086,0.343181768,1.315500353,0.73783365,2.407479181,0.512472036,DB0017510007739_,0.668509134,0.27421709,NA,10007739,Cataract,10015919,Eye disorders,Eye,pravastatin,DB00175
,48310,DB00404,10007739,65,19827,18,9844,0.026396475,1.792865582,1.049927957,3.213731373,0.076636938,DB0040410007739_,2.568676105,0.583815223,NA,10007739,Cataract,10015919,Eye disorders,Eye,alprazolam,DB00404
,48312,DB06643,10007739,69,52352,22,7493,0.002164801,0.448907061,0.274194526,0.762493563,0.010383537,DB0664310007739_,4.567533728,-0.800939403,NA,10007739,Cataract,10015919,Eye disorders,Eye,denosumab,DB06643
,48316,DB01327,10013700,86,577,30,727,7.01868789647706e-10,3.608753459,2.319108227,5.74990315,2.00637532744861e-08,DB0132710013700_,17.72435097,1.283362411,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,cefazolin,DB01327
,48318,DB00737,10047340,87,2714,20,912,0.141123663,1.461573457,0.885071863,2.524785048,0.271455213,DB0073710047340_,1.303958113,0.379513566,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,meclizine,DB00737
,48319,DB00863,10047340,41,10632,11,5829,0.04076443,2.043399939,1.030540651,4.411558687,0.10716002,DB0086310047340_,2.233432052,0.714615057,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,ranitidine,DB00863
,48321,DB00230,10069327,49,19625,28,8623,0.266690489,0.768913343,0.473451147,1.271496655,0.428887975,DB0023010069327_,0.846559524,-0.262777004,NA,10069327,Product quality issue,10077536,Product issues,Prod,pregabalin,DB00230
,48322,DB00341,10069327,82,11323,36,5032,1,1.012259953,0.675173844,1.544691557,1,DB0034110069327_,0,0.012185409,NA,10069327,Product quality issue,10077536,Product issues,Prod,cetirizine,DB00341
,48324,DB00863,10069327,35,10638,25,5815,0.343774588,0.765308709,0.444656975,1.335326998,0.513036247,DB0086310069327_,0.667408779,-0.267475986,NA,10069327,Product quality issue,10077536,Product issues,Prod,ranitidine,DB00863
,48325,DB00924,10002855,271,9891,51,4200,1.37962738410347e-08,2.256252994,1.66367193,3.11296645,3.00567805977288e-07,DB0092410002855_,15.01759246,0.81370547,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,48327,DB00924,10022437,242,9920,71,4180,0.007006905,1.436228012,1.095158689,1.90334113,0.026814663,DB0092410022437_,3.61880643,0.362020241,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,48328,DB01067,10022437,88,4273,66,4757,0.018041873,1.484282875,1.063449861,2.080335068,0.056941291,DB0106710022437_,2.865734526,0.394931743,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,glipizide,DB01067
,48329,DB01076,10022437,381,25366,329,25254,0.063994637,1.152937371,0.991151273,1.341687781,0.150637983,DB0107610022437_,1.892875784,0.142312922,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,48331,DB00230,10003246,194,19480,44,8607,2.76676565508269e-05,1.948063082,1.396663521,2.770518112,0.00026426,DB0023010003246_,8.238575946,0.666835588,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,48332,DB00635,10003246,271,32782,83,23711,3.63211167785614e-13,2.361539193,1.839240769,3.059175337,1.72484291693674e-11,DB0063510003246_,24.78330004,0.859313607,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,48333,DB00678,10003246,95,15504,39,10685,0.00613293,1.678729758,1.14394746,2.506022901,0.024083309,DB0067810003246_,3.726236233,0.518037411,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,48334,DB00512,10003997,33,4704,45,5053,0.308360982,0.787761294,0.486080729,1.264709886,0.475638905,DB0051210003997_,0.743096316,-0.238560161,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,vancomycin,DB00512
,48335,DB00635,10003997,87,32966,91,23703,0.014667913,0.687425593,0.506170268,0.933063562,0.048435439,DB0063510003997_,3.027523528,-0.374801683,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,prednisone,DB00635
,48337,DB00635,10007515,126,32927,159,23635,2.34290108231643e-06,0.568841776,0.446349892,0.723636139,3.0396423962827e-05,DB0063510007515_,10.40118559,-0.564152957,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,prednisone,DB00635
,48345,DB00512,10044223,33,4704,29,5069,0.446347718,1.226198732,0.720606586,2.096947075,0.614157449,DB0051210044223_,0.487503951,0.203918922,NA,10044223,Toxic epidermal necrolysis,10040785,Skin and subcutaneous tissue disorders,Skin,vancomycin,DB00512
,48349,DB00016,10003988,57,2705,33,2257,0.108911487,1.4410983,0.918969973,2.293167101,0.224397235,DB0001610003988_,1.494337427,0.365405531,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,erythropoietin,DB00016
,48354,DB00480,10005911,48,67380,53,67609,0.690761029,0.908749625,0.601806731,1.36914361,0.813470145,DB0048010005911_,0.206446052,-0.095685663,NA,10005911,Body temperature increased,10022891,Investigations,Inv,lenalidomide,DB00480
,48358,DB00338,10016825,224,33450,91,22181,6.38667806890902e-05,1.632252786,1.272988924,2.107611479,0.000542891,DB0033810016825_,7.518601791,0.489961138,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,omeprazole,DB00338
,48360,DB00480,10016825,116,67312,76,67586,0.003795357,1.532515411,1.137557871,2.074877262,0.016351576,DB0048010016825_,4.113430972,0.426910445,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,lenalidomide,DB00480
,48361,DB00497,10016825,67,19200,35,16340,0.021692126,1.629110659,1.066347915,2.528186981,0.065934009,DB0049710016825_,2.719100896,0.488034258,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,oxycodone,DB00497
,48365,DB00480,10019303,143,67285,142,67520,0.952749959,1.010560236,0.7952819,1.284120997,0.990763463,DB0048010019303_,0.009279458,0.010504866,NA,10019303,Heart rate increased,10022891,Investigations,Inv,lenalidomide,DB00480
,48368,DB00480,10020751,453,66975,365,67297,0.001787902,1.247058097,1.083595918,1.435906887,0.008870328,DB0048010020751_,4.72504345,0.220787255,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,lenalidomide,DB00480
,48369,DB00497,10020751,102,19165,48,16327,0.00054209,1.810290645,1.27162139,2.608879465,0.003299487,DB0049710020751_,5.713988178,0.59348741,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,oxycodone,DB00497
,48370,DB00016,10028334,37,2725,27,2263,0.704957949,1.137994496,0.672074361,1.950008167,0.823090269,DB0001610028334_,0.194689401,0.129267499,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,erythropoietin,DB00016
,48372,DB00497,10028334,232,19035,185,16190,0.521017491,1.066639027,0.874401692,1.302562837,0.679987326,DB0049710028334_,0.385681119,0.064512609,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,48375,DB00016,10033371,93,2669,40,2250,0.000377521,1.959718534,1.332854188,2.927388735,0.002445627,DB0001610033371_,6.013453874,0.672800858,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,48379,DB00338,10051792,106,33568,68,22204,0.876941792,1.031106236,0.752942188,1.420220569,0.947522962,DB0033810051792_,0.053904108,0.030632241,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,48381,DB00480,10051792,36,67392,40,67622,0.730965444,0.903077364,0.559259212,1.453452086,0.843508064,DB0048010051792_,0.170185816,-0.101947055,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,48383,DB00338,10061623,220,33454,156,22116,0.525974517,0.932303706,0.755357128,1.152934904,0.683909976,DB0033810061623_,0.379928983,-0.070096653,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,48385,DB00497,10061623,101,19166,96,16279,0.431547058,0.893610209,0.668471452,1.195184952,0.599989682,DB0049710061623_,0.510842821,-0.112485606,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,48396,DB06626,10003549,32,656,46,1406,0.107598377,1.490716729,0.909548122,2.417066844,0.222572073,DB0662610003549_,1.502504306,0.399257031,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,axitinib,DB06626
,48412,DB00060,10028836,44,9464,8,2457,0.490694042,1.42783622,0.663754046,3.516281705,0.653918724,DB0006010028836_,0.424772211,0.356160165,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,48413,DB00060,10039203,78,9430,24,2441,0.4609144,0.841279971,0.525275549,1.393597909,0.628243923,DB0006010039203_,0.464826775,-0.172830772,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,interferon beta-1a,DB00060
,48418,DB08895,10020751,307,27807,39,6607,0.000109886,1.870300278,1.335742471,2.684569626,0.000864521,DB0889510020751_,7.053335063,0.626098994,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,tofacitinib,DB08895
,48419,DB00471,10033425,301,13888,72,5393,0.000144455,1.623394372,1.248841666,2.133962344,0.001092537,DB0047110033425_,6.819252467,0.484519249,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,48421,DB00635,10048959,797,32256,337,23457,1.9657113044828e-17,1.719826683,1.5105241,1.961468375,1.59717841231315e-15,DB0063510048959_,34.07053781,0.54222352,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,48423,DB08895,10048959,972,27142,170,6476,0.000173351,1.364194259,1.155175048,1.61889147,0.001278486,DB0889510048959_,6.662078735,0.310563968,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,48431,DB01156,10048393,127,13495,19,6309,2.33892287505573e-07,3.124752377,1.918536486,5.366374686,3.90960812533163e-06,DB0115610048393_,12.45207341,1.139355041,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,48432,DB00060,10000059,61,9447,11,2454,0.30764393,1.44046451,0.749752928,3.040945325,0.474805983,DB0006010000059_,0.744849016,0.364965638,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,interferon beta-1a,DB00060
,48434,DB00216,10027599,90,833,8,100,0.601786356,1.350180209,0.63116722,3.318396827,0.746013432,DB0021610027599_,0.293011674,0.300238072,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,eletriptan,DB00216
,48436,DB00203,10023424,49,13829,7,8931,1.4421738833828e-05,4.520482549,2.035518263,11.83493324,0.000149921,DB0020310023424_,8.805401656,1.508618747,female,10023424,Kidney infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,48437,DB08932,10023424,72,19371,10,6587,0.004845481,2.448398938,1.256476798,5.32507476,0.019962924,DB0893210023424_,3.913878524,0.895434316,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,48438,DB00203,10038428,108,13770,49,8889,0.040473252,1.422787559,1.004999028,2.039375925,0.106597137,DB0020310038428_,2.238698629,0.352618017,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,sildenafil,DB00203
,48442,DB00758,10042674,77,8223,42,10032,2.57706292720217e-05,2.236571373,1.514479689,3.343561407,0.000247898,DB0075810042674_,8.302493622,0.804944056,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,48445,DB00682,10013700,201,19258,81,16283,6.05965174288539e-09,2.098051225,1.611824337,2.752726361,1.43171187471229e-07,DB0068210013700_,15.75922481,0.741008926,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,warfarin,DB00682
,48447,DB00682,10037660,519,18940,250,16114,6.20542825495536e-14,1.766211377,1.513601734,2.065252134,3.26844415588301e-12,DB0068210037660_,26.44670704,0.568836787,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,48448,DB00381,10069326,53,29307,42,22845,1,0.983659801,0.643551759,1.512139675,1,DB0038110069326_,0,-0.016475172,NA,10069326,Product substitution issue,10077536,Product issues,Prod,amlodipine,DB00381
,48449,DB00338,10005734,106,33568,66,22206,0.755157966,1.062453,0.773699897,1.468136099,0.862589717,DB0033810005734_,0.147816116,0.060580386,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,omeprazole,DB00338
,48454,DB00338,10033318,155,33519,89,22183,0.295099774,1.152616008,0.881953881,1.514006259,0.461008444,DB0033810033318_,0.77433892,0.142034148,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,omeprazole,DB00338
,48456,DB00722,10033318,67,25336,66,25966,0.862283173,1.040405587,0.729042316,1.485037587,0.93601409,DB0072210033318_,0.066124749,0.039610625,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,lisinopril,DB00722
,48457,DB00996,10033318,159,38794,70,22355,0.063401925,1.308902627,0.98162395,1.760484452,0.149638108,DB0099610033318_,1.899535514,0.269189097,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,gabapentin,DB00996
,48458,DB01015,10033318,44,9843,28,9353,0.099423306,1.49316359,0.908203597,2.492816748,0.209999726,DB0101510033318_,1.560649054,0.400897084,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,48459,DB01076,10033318,140,25607,83,25500,0.000161518,1.679671926,1.270492119,2.232451837,0.001201804,DB0107610033318_,6.723931876,0.518598492,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,48466,DB00343,10053762,164,8572,86,5009,0.466793733,1.114340205,0.851124115,1.467529518,0.633395242,DB0034310053762_,0.456660657,0.108262486,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,48478,DB00635,10024378,77,32976,93,23701,0.000781873,0.595100885,0.433978083,0.814056741,0.004488704,DB0063510024378_,5.406191166,-0.519024333,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,48480,DB00555,10001760,53,6994,11,3475,0.007144923,2.393768856,1.233780554,5.089725909,0.027233801,DB0055510001760_,3.60329638,0.872869051,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,lamotrigine,DB00555
,48484,DB00537,10072268,33,7524,24,4274,0.407398576,0.781099955,0.447186299,1.383073241,0.576908316,DB0053710072268_,0.550071923,-0.247052154,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,ciprofloxacin,DB00537
,48485,DB00695,10072268,35,28014,35,20493,0.225720704,0.731541509,0.444429887,1.204100708,0.380544462,DB0069510072268_,0.966152256,-0.312601315,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,furosemide,DB00695
,48486,DB00722,10072268,36,25367,40,25992,0.732291493,0.922200778,0.570963044,1.484584561,0.84442659,DB0072210072268_,0.169097474,-0.080992315,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,lisinopril,DB00722
,48491,DB00381,10003119,44,29316,54,22833,0.025141392,0.634640823,0.416173096,0.963123838,0.073804052,DB0038110003119_,2.60634164,-0.454696074,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,amlodipine,DB00381
,48494,DB01076,10003119,40,25707,51,25532,0.249605757,0.778980387,0.501551874,1.202417003,0.409096638,DB0107610003119_,0.893803873,-0.249769411,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,48497,DB01076,10003658,301,25446,428,25155,1.41805593843673e-06,0.6952369,0.597284789,0.808435141,1.95932212045067e-05,DB0107610003658_,10.84032691,-0.363502629,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,48499,DB00046,10006451,49,5410,20,4672,0.004958842,2.115584266,1.232471288,3.763592941,0.020332759,DB0004610006451_,3.895521952,0.749331023,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,insulin lispro,DB00046
,48500,DB00047,10006451,76,9209,37,8481,0.001257235,1.891601821,1.259446598,2.886261411,0.006639159,DB0004710006451_,5.014770009,0.637423994,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,48502,DB00588,10006451,380,16144,102,8366,7.25714492059243e-10,1.930544088,1.544987249,2.430435808,2.07116236957407e-08,DB0058810006451_,17.69257076,0.657801874,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,48504,DB01076,10006451,257,25490,114,25469,1.02351213897077e-13,2.252503214,1.798451155,2.835600642,5.2238867131741e-12,DB0107610006451_,25.97777941,0.812042137,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,48506,DB00047,10008190,106,9179,101,8417,0.833782795,0.962369138,0.724630568,1.278826558,0.913682907,DB0004710008190_,0.090271697,-0.038357183,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,48511,DB00046,10009033,29,5430,39,4653,0.067955146,0.637221995,0.379364126,1.059150984,0.157617561,DB0004610009033_,1.847583679,-0.450637184,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin lispro,DB00046
,48512,DB00047,10009033,45,9240,49,8469,0.409851947,0.841746976,0.548264104,1.289680337,0.579315897,DB0004710009033_,0.545907359,-0.172275814,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,48514,DB00332,10009033,98,2586,62,1594,0.868686544,0.974295056,0.697116994,1.370300394,0.94152633,DB0033210009033_,0.060252965,-0.026041089,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipratropium,DB00332
,48515,DB00381,10009033,175,29185,104,22783,0.02930685,1.313570121,1.02403459,1.691978287,0.083172794,DB0038110009033_,2.486834984,0.272748713,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,48527,DB00310,10013968,35,909,25,756,0.599625271,1.164254007,0.67045466,2.049058066,0.744258289,DB0031010013968_,0.295367142,0.152080544,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,chlorthalidone,DB00310
,48528,DB06626,10013968,12,676,44,1408,0.083860335,0.568181699,0.271335372,1.103212237,0.184844352,DB0662610013968_,1.688241147,-0.565314019,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,axitinib,DB06626
,48529,DB00310,10016256,58,886,48,733,1,0.999662065,0.661257845,1.517103265,1,DB0031010016256_,0,-0.000337992,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,chlorthalidone,DB00310
,48530,DB00590,10016256,54,722,112,1840,0.248350198,1.228590877,0.860902823,1.736127525,0.407712507,DB0059010016256_,0.897192992,0.205867884,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,doxazosin,DB00590
,48535,DB00588,10018964,68,16456,60,8408,0.002597662,0.579056457,0.402778644,0.834420961,0.01202044,DB0058810018964_,4.421146784,-0.546355299,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,48537,DB01076,10018964,52,25695,63,25520,0.305283177,0.819779891,0.55642789,1.203223359,0.472108375,DB0107610018964_,0.750546712,-0.198719401,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,48539,DB00046,10033425,109,5350,70,4622,0.058558002,1.345213696,0.98458112,1.848082301,0.140790952,DB0004610033425_,1.960479097,0.296552882,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin lispro,DB00046
,48541,DB00590,10033425,17,759,35,1917,0.53484274,1.226624595,0.640326652,2.265005992,0.691405468,DB0059010033425_,0.369028843,0.204266166,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,doxazosin,DB00590
,48542,DB06626,10033425,19,669,47,1405,0.594904479,0.849071348,0.466701615,1.488351802,0.74058416,DB0662610033425_,0.300315999,-0.163612058,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,axitinib,DB06626
,48544,DB00047,10062237,52,9233,64,8454,0.114121466,0.743964504,0.5052104,1.091104615,0.23230844,DB0004710062237_,1.459689309,-0.295761956,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,insulin glargine,DB00047
,48547,DB00381,10062237,166,29194,148,22739,0.253881532,0.873627022,0.69527808,1.098561959,0.414424846,DB0038110062237_,0.880863634,-0.135101743,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,48553,DB00169,10050031,51,38640,17,18158,0.243135617,1.409800368,0.800484304,2.604663337,0.401458616,DB0016910050031_,0.912650825,0.343448111,NA,10050031,Muscle strain,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,48560,DB00005,10011968,181,127901,62,42357,0.823796558,0.966801566,0.720656532,1.312107332,0.906591828,DB0000510011968_,0.098062954,-0.03376201,NA,10011968,Decreased immune responsiveness,10021428,Immune system disorders,Immun,etanercept,DB00005
,48562,DB00005,10017918,298,127784,60,42359,0.000290025,1.646331232,1.243718161,2.211020584,0.001962244,DB0000510017918_,6.233666678,0.498549316,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,etanercept,DB00005
,48564,DB00005,10021866,40,128042,10,42409,0.514049941,1.324829926,0.650996706,2.9714446,0.674039843,DB0000510021866_,0.394466055,0.281284094,NA,10021866,Infection susceptibility increased,10021881,Infections and infestations,Infec,etanercept,DB00005
,48566,DB01097,10022000,61,6204,13,1490,0.76932877,1.126923274,0.61050865,2.24204587,0.873663127,DB0109710022000_,0.135060416,0.119491153,NA,10022000,Influenza,10021881,Infections and infestations,Infec,leflunomide,DB01097
,48568,DB01097,10028810,67,6198,8,1495,0.056373714,2.019926189,0.965602348,4.880937508,0.136765249,DB0109710028810_,1.989489337,0.703060971,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,leflunomide,DB01097
,48569,DB00005,10029202,80,128002,31,42388,0.44358564,0.854610078,0.557953307,1.339085608,0.611694315,DB0000510029202_,0.491522607,-0.157109963,NA,10029202,Nervous system disorder,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,48577,DB00203,10025127,130,13748,54,8884,0.006222178,1.5556443,1.12300552,2.18073694,0.024368615,DB0020310025127_,3.714459238,0.441889801,NA,10025127,Lung transplant,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,48582,DB06403,10007815,126,21345,28,6633,0.127707954,1.398349716,0.921634214,2.190336055,0.252410224,DB0640310007815_,1.376699642,0.335292767,NA,10007815,Catheterisation cardiac,10022891,Investigations,Inv,ambrisentan,DB06403
,48589,DB00787,10001760,164,16836,35,17213,7.13910815818096e-22,4.790195786,3.307131091,7.117710872,8.95711016409482e-20,DB0078710001760_,43.85925421,1.566571284,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,48596,DB00264,10000081,363,29244,250,24642,0.014441014,1.223499615,1.03765293,1.444497646,0.047791256,DB0026410000081_,3.040912576,0.201715289,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,48597,DB00727,10000081,64,3779,46,4127,0.034255528,1.519335189,1.021234405,2.275874611,0.093909736,DB0072710000081_,2.365421211,0.418272864,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,nitroglycerin,DB00727
,48598,DB13961,10000081,124,9333,74,6340,0.422878361,1.138331489,0.845133224,1.542221119,0.591809058,DB1396110000081_,0.524571234,0.129563584,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,48607,DB00051,10060795,171,25560,82,11338,0.584493177,0.925038565,0.706163683,1.220032201,0.732270592,DB0005110060795_,0.311605172,-0.07791985,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,adalimumab,DB00051
,48609,DB00108,10002034,72,10122,8,3287,0.001571935,2.922591509,1.404506634,7.034266131,0.007988846,DB0010810002034_,4.829708919,1.072470726,female,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,natalizumab,DB00108
,48611,DB00437,10002855,72,6849,79,11467,0.011134315,1.525811253,1.091487334,2.130349007,0.038779046,DB0043710002855_,3.249875226,0.422526238,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,allopurinol,DB00437
,48612,DB01136,10002855,126,9758,66,11049,2.7469609666068e-07,2.161603099,1.590270004,2.961163041,4.51133202169696e-06,DB0113610002855_,12.3089181,0.770850122,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,carvedilol,DB01136
,48614,DB14513,10002855,127,7050,30,3534,0.00010862,2.121941905,1.412900415,3.280586843,0.000855836,DB1451310002855_,7.063432155,0.752331663,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,magnesium,DB14513
,48627,DB00404,10005425,53,19839,13,9849,0.018575739,2.023931327,1.087739103,4.049251042,0.058294339,DB0040410005425_,2.842250283,0.705041821,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,alprazolam,DB00404
,48632,DB00996,10005425,91,38862,35,22390,0.041735117,1.497957466,1.003711722,2.280963484,0.109193006,DB0099610005425_,2.214638263,0.404102491,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,gabapentin,DB00996
,48634,DB01104,10005425,41,15422,14,7272,0.385102367,1.380936469,0.736854285,2.744287898,0.555230965,DB0110410005425_,0.588371098,0.32276187,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,sertraline,DB01104
,48645,DB00996,10005619,50,38903,9,22416,0.000387554,3.201066064,1.558109385,7.405869918,0.002499533,DB0099610005619_,5.991651291,1.163483899,female,10005619,Blood iron decreased,10022891,Investigations,Inv,gabapentin,DB00996
,48667,DB01098,10010305,78,8071,61,7148,0.495278516,1.132443504,0.798404706,1.612654814,0.657577764,DB0109810010305_,0.419192249,0.124377691,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,rosuvastatin,DB01098
,48669,DB01409,10010305,64,5967,39,3927,0.761769935,1.079996154,0.712598093,1.655499936,0.867966655,DB0140910010305_,0.141601982,0.07695748,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,tiotropium,DB01409
,48670,DB14513,10010305,52,7125,42,3522,0.020602709,0.612025213,0.398876976,0.944133681,0.063267973,DB1451310010305_,2.760376028,-0.490981799,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,magnesium,DB14513
,48671,DB00404,10013950,134,19758,48,9814,0.057713503,1.386645464,0.989307109,1.972515977,0.139174731,DB0040410013950_,1.972025079,0.326887495,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,48673,DB00863,10013950,111,10562,48,5792,0.18275941,1.268146661,0.894655384,1.821204542,0.327392563,DB0086310013950_,1.116595329,0.237556512,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,48674,DB00924,10013950,81,10081,27,4224,0.341122001,1.25697698,0.802944881,2.024940919,0.510285224,DB0092410013950_,0.672785447,0.228709616,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,48675,DB00996,10013950,217,38736,94,22331,0.021224157,1.330832217,1.039465696,1.714816641,0.064809737,DB0099610013950_,2.736299431,0.285804474,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,48676,DB01069,10013950,60,6640,18,2377,0.605793937,1.19324475,0.69326748,2.152236614,0.748838113,DB0106910013950_,0.289232457,0.176676277,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,promethazine,DB01069
,48677,DB01104,10013950,96,15367,48,7238,0.720995794,0.942022049,0.658667608,1.362994084,0.83543276,DB0110410013950_,0.179805413,-0.059726598,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,48678,DB01136,10013950,49,9835,52,11063,0.84173548,1.059994033,0.701900851,1.598540828,0.919328406,DB0113610013950_,0.084111869,0.058263279,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,48680,DB14513,10013950,38,7139,17,3547,0.775706207,1.11058705,0.610853251,2.101489074,0.877814798,DB1451310013950_,0.130319644,0.104888749,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,48685,DB00996,10014184,39,38914,12,22413,0.058603389,1.871858503,0.959968605,3.927976619,0.140887189,DB0099610014184_,1.959795785,0.626931789,NA,10014184,Eczema,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,48712,DB00996,10018627,57,38896,49,22376,0.043237354,0.669233066,0.448559637,1.001579562,0.112141087,DB0099610018627_,2.187997496,-0.401622899,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,48716,DB01136,10018627,28,9856,46,11069,0.12915446,0.683623329,0.411102382,1.118123829,0.254408347,DB0113610018627_,1.368814638,-0.380348201,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,carvedilol,DB01136
,48718,DB01394,10018627,77,1363,116,1887,0.599681744,0.918987889,0.67394839,1.247573372,0.74427531,DB0139410018627_,0.295344273,-0.084482335,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,colchicine,DB01394
,48747,DB00404,10020751,179,19713,35,9827,4.73799094745735e-08,2.549418467,1.765297432,3.778190869,9.19779114135276e-07,DB0040410020751_,13.89913229,0.935865281,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,alprazolam,DB00404
,48748,DB00437,10020751,61,6860,66,11480,0.016496002,1.546591663,1.072326444,2.227612641,0.053084895,DB0043710020751_,2.935862863,0.436053582,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,allopurinol,DB00437
,48749,DB00557,10020751,82,5905,17,3050,0.000253403,2.491197535,1.461787715,4.48991483,0.001756048,DB0055710020751_,6.344689264,0.912763533,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,hydroxyzine,DB00557
,48750,DB00863,10020751,131,10542,39,5801,0.000503601,1.848296775,1.281860121,2.719114591,0.003108405,DB0086310020751_,5.77364565,0.614264553,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ranitidine,DB00863
,48751,DB00924,10020751,99,10063,23,4228,0.009277383,1.808419802,1.137908186,2.98849504,0.03351611,DB0092410020751_,3.395729051,0.592453427,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,cyclobenzaprine,DB00924
,48752,DB00996,10020751,338,38615,106,22319,1.0787673148748e-08,1.842999114,1.476527868,2.316106673,2.4101486503599e-07,DB0099610020751_,15.23840722,0.611394198,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,gabapentin,DB00996
,48753,DB01069,10020751,82,6618,10,2385,0.000323072,2.955057826,1.524677896,6.402238197,0.002143619,DB0106910020751_,6.145259814,1.083518219,female,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,promethazine,DB01069
,48754,DB01104,10020751,133,15330,28,7258,4.01786633931532e-05,2.248822967,1.485705304,3.515659061,0.000366191,DB0110410020751_,7.91235425,0.810406954,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,sertraline,DB01104
,48755,DB01136,10020751,78,9806,57,11058,0.015142782,1.54309048,1.08140033,2.213464806,0.049688288,DB0113610020751_,3.001986024,0.433787211,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,carvedilol,DB01136
,48756,DB01222,10020751,131,9143,48,5357,0.004932083,1.599005001,1.138431217,2.278835196,0.020249891,DB0122210020751_,3.899605855,0.469381561,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,budesonide,DB01222
,48758,DB14513,10020751,72,7105,13,3551,0.000283917,2.76784639,1.518251324,5.454776646,0.001928954,DB1451310020751_,6.250777208,1.018069541,female,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,magnesium,DB14513
,48759,DB00863,10020772,147,10526,68,5772,0.281441777,1.185379929,0.881717518,1.607299676,0.445376105,DB0086310020772_,0.808836174,0.170063338,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ranitidine,DB00863
,48760,DB01069,10020772,103,6597,29,2366,0.274483267,1.273770849,0.834080609,2.00111289,0.437716435,DB0106910020772_,0.826183987,0.241981674,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,promethazine,DB01069
,48761,DB01222,10020772,144,9130,67,5338,0.13135589,1.256598683,0.932055399,1.708673339,0.25768852,DB0122210020772_,1.356003711,0.228408613,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,budesonide,DB01222
,48763,DB01409,10020772,85,5946,25,3941,0.000180273,2.253340635,1.425229122,3.681473925,0.001321011,DB0140910020772_,6.629358151,0.812413842,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,tiotropium,DB01409
,48776,DB00437,10028334,95,6826,115,11431,0.021665477,1.383323007,1.04112649,1.834408881,0.065873575,DB0043710028334_,2.720017897,0.324488581,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,allopurinol,DB00437
,48777,DB00557,10028334,92,5895,33,3034,0.086372753,1.434793397,0.951853716,2.210944069,0.189003987,DB0055710028334_,1.66598717,0.361020864,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxyzine,DB00557
,48778,DB00924,10028334,234,9928,57,4194,0.00012108,1.734175076,1.290115094,2.364732591,0.000939091,DB0092410028334_,6.970597769,0.55053184,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,48779,DB01098,10028334,185,7964,128,7081,0.034105373,1.285042075,1.01780749,1.626520974,0.093605486,DB0109810028334_,2.368666288,0.250791461,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,48780,DB01136,10028334,140,9744,100,11015,0.000540758,1.582564461,1.21379148,2.069823269,0.003292902,DB0113610028334_,5.71598591,0.459046608,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,carvedilol,DB01136
,48782,DB01409,10028334,77,5954,44,3922,0.513042687,1.152778377,0.783983664,1.713599515,0.673105244,DB0140910028334_,0.395853581,0.142175008,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,tiotropium,DB01409
,48783,DB14513,10028334,220,6957,83,3481,0.0302954,1.326241474,1.022190039,1.734195594,0.085317897,DB1451310028334_,2.461371039,0.282348982,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,48784,DB01222,10028813,506,8768,163,5242,2.32357220730182e-12,1.855845069,1.547125415,2.235546435,9.86673594005303e-11,DB0122210028813_,23.03926693,0.618340155,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,48785,DB01394,10028813,90,1350,70,1933,0.000203483,1.840569499,1.32099083,2.573315961,0.001462149,DB0139410028813_,6.527848205,0.610075034,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,colchicine,DB01394
,48786,DB01409,10028813,323,5708,143,3823,4.44078314650889e-05,1.512757031,1.233122908,1.86314381,0.000399473,DB0140910028813_,7.825364599,0.413933834,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,tiotropium,DB01409
,48813,DB00557,10037844,189,5798,81,2986,0.191603377,1.201626125,0.917834216,1.584976885,0.338628724,DB0055710037844_,1.082850982,0.183675743,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxyzine,DB00557
,48814,DB01222,10037844,264,9010,123,5282,0.037335707,1.258215722,1.009198866,1.575779856,0.100257349,DB0122210037844_,2.300014913,0.229694623,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,budesonide,DB01222
,48829,DB00404,10041466,70,19822,25,9837,0.189807176,1.389544325,0.868331552,2.291648113,0.336281829,DB0040410041466_,1.089805695,0.32897587,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,48833,DB00924,10041466,43,10119,13,4238,0.378329007,1.385230376,0.730246668,2.811100781,0.548333314,DB0092410041466_,0.60087194,0.325866462,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,48836,DB01104,10041466,61,15402,20,7266,0.189047105,1.438848854,0.855360599,2.51945926,0.335342364,DB0110410041466_,1.092603288,0.363843387,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,48842,DB00437,10046571,172,6749,134,11412,2.31503345686524e-11,2.170366657,1.717880361,2.74662447,8.33570608406888e-10,DB0043710046571_,20.9053027,0.77489612,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,allopurinol,DB00437
,48843,DB00557,10046571,138,5849,17,3050,4.88056872856158e-11,4.232272692,2.543463201,7.489368778,1.67365621696336e-09,DB0055710046571_,20.20825525,1.442739128,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,hydroxyzine,DB00557
,48844,DB00863,10046571,249,10424,60,5780,8.8048063685058e-10,2.301028357,1.726025547,3.109201818,2.47523353364893e-08,DB0086310046571_,17.514346,0.833356135,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ranitidine,DB00863
,48845,DB01136,10046571,263,9621,109,11006,1.60189796967132e-20,2.760059888,2.195579832,3.488847419,1.7617526415402e-18,DB0113610046571_,40.88022254,1.015252378,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,carvedilol,DB01136
,48847,DB00404,10047924,87,19805,26,9836,0.021252478,1.661815364,1.060934591,2.685936658,0.064884299,DB0040410047924_,2.735149613,0.507910597,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,48848,DB00437,10047924,36,6885,39,11507,0.072294805,1.542653127,0.951933732,2.49372907,0.165276708,DB0043710047924_,1.800134191,0.433503744,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,48850,DB00996,10047924,129,38824,48,22377,0.009705575,1.548984232,1.103526333,2.206024376,0.034751538,DB0099610047924_,3.359531452,0.437599382,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,48851,DB01069,10047924,41,6659,9,2386,0.200756169,1.632312816,0.779939971,3.825678452,0.349867456,DB0106910047924_,1.050200894,0.489997915,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,promethazine,DB01069
,48853,DB01104,10047924,57,15406,19,7267,0.218451991,1.415098702,0.82859771,2.520802241,0.37166842,DB0110410047924_,0.989753166,0.347199282,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,48854,DB01136,10047924,40,9844,26,11089,0.035007277,1.732972369,1.031016049,2.960188543,0.095426272,DB0113610047924_,2.349401354,0.549838066,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,48873,DB00996,10062060,43,38910,18,22407,0.288474338,1.375676224,0.776689473,2.534910288,0.453501674,DB0099610062060_,0.790756319,0.31894541,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,48883,DB00863,10068319,89,10584,28,5812,0.008719094,1.745396955,1.128678982,2.776402777,0.031917189,DB0086310068319_,3.444610585,0.556982011,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,48884,DB00924,10068319,82,10080,19,4232,0.020875992,1.811881262,1.088270552,3.165842285,0.063927939,DB0092410068319_,2.749998789,0.594365677,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,48885,DB00996,10068319,208,38745,60,22365,8.12171384534314e-07,2.001061023,1.49415315,2.714814123,1.19228845811139e-05,DB0099610068319_,11.33705093,0.693677551,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,48886,DB01069,10068319,62,6638,12,2383,0.04715727,1.854760868,0.987677663,3.78874645,0.119755723,DB0106910068319_,2.122301252,0.617755776,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,promethazine,DB01069
,48887,DB01098,10068319,55,8094,23,7186,0.001995635,2.122879564,1.281669893,3.623573562,0.009703624,DB0109810068319_,4.635255839,0.752773452,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,48889,DB01409,10068319,61,5970,23,3943,0.02452745,1.751583947,1.066367218,2.970815205,0.072448691,DB0140910068319_,2.624876681,0.560520491,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,48891,DB00335,10006451,94,8372,30,5435,0.00057288,2.03402116,1.333734525,3.183549688,0.003458067,DB0033510006451_,5.667045494,0.710014701,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,atenolol,DB00335
,48892,DB00215,10046306,77,11026,17,5259,0.002664682,2.160277377,1.264110264,3.901439177,0.012273928,DB0021510046306_,4.400277962,0.770236629,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,citalopram,DB00215
,48893,DB00335,10046306,53,8413,24,5441,0.160941518,1.428175842,0.865122545,2.422028197,0.298756842,DB0033510046306_,1.208125273,0.356397995,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,atenolol,DB00335
,48894,DB00480,10024288,23,67405,46,67616,0.007611445,0.501570441,0.290134508,0.844757845,0.028621866,DB0048010024288_,3.553584314,-0.690011221,NA,10024288,Leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,48897,DB00327,10000087,65,6073,26,4236,0.018055355,1.74369168,1.088839857,2.868554686,0.056979831,DB0032710000087_,2.865057909,0.556004521,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,hydromorphone,DB00327
,48898,DB00421,10000087,178,8725,55,5197,1.07942864086478e-05,1.927638997,1.414243158,2.663657275,0.000115902,DB0042110000087_,9.06276653,0.656295936,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,48899,DB00571,10000087,49,5074,22,2587,0.705730479,1.135557428,0.672044732,1.976855765,0.823674283,DB0057110000087_,0.193980115,0.127123656,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,propranolol,DB00571
,48900,DB01225,10000087,44,5000,23,4617,0.027149998,1.766396354,1.041938537,3.069949282,0.078331743,DB0122510000087_,2.546802357,0.568941513,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,48913,DB00338,10018830,56,33618,24,22248,0.085962009,1.544159979,0.941195818,2.605957651,0.18827046,DB0033810018830_,1.669875734,0.43448006,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,48915,DB00421,10018830,32,8871,20,5232,0.885919068,0.943663469,0.522791687,1.742854566,0.952535694,DB0042110018830_,0.048627699,-0.057985671,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,48922,DB00398,10047700,55,672,98,1440,0.323830239,1.202501696,0.837140025,1.713180369,0.49228639,DB0039810047700_,0.708694638,0.184404133,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sorafenib,DB00398
,48923,DB01225,10047700,192,4852,129,4511,0.005304436,1.383718401,1.096954697,1.74998196,0.021446856,DB0122510047700_,3.842177231,0.324774369,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,48924,DB01261,10047700,122,3659,77,3226,0.025294682,1.396849923,1.037283088,1.890628048,0.074150528,DB0126110047700_,2.601658092,0.334219647,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sitagliptin,DB01261
,48925,DB00327,10047895,120,6018,93,4169,0.439048315,0.893888803,0.674092784,1.188384514,0.607436637,DB0032710047895_,0.49850741,-0.112173893,NA,10047895,Weight decreased,10022891,Investigations,Inv,hydromorphone,DB00327
,48926,DB00706,10047895,25,1050,388,15537,0.918465864,0.953425769,0.606459543,1.437223948,0.963960728,DB0070610047895_,0.036704724,-0.047693708,NA,10047895,Weight decreased,10022891,Investigations,Inv,tamsulosin,DB00706
,48927,DB01225,10047895,86,4958,73,4567,0.631705512,1.08513311,0.782940984,1.507380052,0.770522721,DB0122510047895_,0.260686136,0.081702662,NA,10047895,Weight decreased,10022891,Investigations,Inv,enoxaparin,DB01225
,48928,DB01261,10047895,83,3698,100,3203,0.029437116,0.718938731,0.528692858,0.975535525,0.08345967,DB0126110047895_,2.483391759,-0.329979139,NA,10047895,Weight decreased,10022891,Investigations,Inv,sitagliptin,DB01261
,48929,DB00327,10054112,60,6078,38,4224,0.681111394,1.097325973,0.71745114,1.69685301,0.807169206,DB0032710054112_,0.21422196,0.092876286,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,hydromorphone,DB00327
,48930,DB00338,10054112,375,33299,222,22050,0.192773404,1.118575194,0.944105319,1.327715642,0.340127467,DB0033810054112_,1.07843483,0.112055727,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,omeprazole,DB00338
,48931,DB00398,10054112,43,684,75,1463,0.31172476,1.226154459,0.813219911,1.829208487,0.479120856,DB0039810054112_,0.735802404,0.203882816,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,sorafenib,DB00398
,48932,DB00421,10054112,188,8715,93,5159,0.170163598,1.196608279,0.926128677,1.555095088,0.311061281,DB0042110054112_,1.167765341,0.179491121,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,spironolactone,DB00421
,48933,DB00433,10054112,39,7617,39,5981,0.304358643,0.785236394,0.489951142,1.258387233,0.471021633,DB0043310054112_,0.752851257,-0.241770468,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,prochlorperazine,DB00433
,48934,DB00571,10054112,36,5087,30,2579,0.049639789,0.608397962,0.363421876,1.025251783,0.124335987,DB0057110054112_,2.084767802,-0.496926069,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,propranolol,DB00571
,48935,DB00706,10054112,13,1062,159,15766,0.52630815,1.213772754,0.630182485,2.145175808,0.684187125,DB0070610054112_,0.379523825,0.193733488,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,tamsulosin,DB00706
,48936,DB01067,10054112,32,4329,41,4782,0.558022204,0.862174819,0.524523228,1.405860994,0.711001896,DB0106710054112_,0.341080182,-0.148297222,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,glipizide,DB01067
,48937,DB01225,10054112,55,4989,29,4611,0.015461139,1.75275026,1.096271176,2.856166874,0.050474576,DB0122510054112_,2.986285522,0.561186131,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,enoxaparin,DB01225
,48938,DB01261,10054112,29,3752,34,3269,0.255369814,0.743176853,0.435760037,1.259895344,0.416091965,DB0126110054112_,0.876848974,-0.296821237,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,sitagliptin,DB01261
,48954,DB00482,10016173,230,8029,69,3002,0.114063432,1.246276747,0.945088351,1.661217296,0.23226205,DB0048210016173_,1.459889019,0.220160504,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,celecoxib,DB00482
,48956,DB00482,10024855,44,8215,20,3051,0.480868274,0.817054783,0.470666642,1.465891756,0.64560336,DB0048210024855_,0.437569957,-0.202049132,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,48957,DB00203,10015090,260,13618,107,8831,6.3067527653733e-05,1.575714381,1.25125259,1.995784059,0.000537265,DB0020310015090_,7.529019823,0.454708744,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,48968,DB00788,10008531,65,9291,29,5032,0.448127673,1.213879331,0.771179055,1.95364724,0.615867581,DB0078810008531_,0.484723305,0.19382129,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,48971,DB06724,10008531,75,7854,39,3880,0.841515109,0.950035048,0.635578362,1.439944447,0.919145009,DB0672410008531_,0.084311379,-0.051256403,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,48976,DB00115,10021143,79,18346,43,10429,0.850828489,1.044384496,0.710892329,1.552670763,0.926372712,DB0011510021143_,0.076478629,0.043427712,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,48977,DB00169,10021143,147,38544,112,18063,0.000134669,0.61507983,0.477444606,0.794238855,0.001027364,DB0016910021143_,6.880758955,-0.486003215,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,48979,DB00788,10021143,32,9324,25,5036,0.166953856,0.691332122,0.396455313,1.218366656,0.306744785,DB0078810021143_,1.181739195,-0.369134931,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,naproxen,DB00788
,48982,DB06724,10021143,46,7883,44,3875,0.002194849,0.513920892,0.331809688,0.796886169,0.010493201,DB0672410021143_,4.557027795,-0.665685932,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,48984,DB00007,10028411,25,1922,51,4401,0.618159642,1.122423343,0.664320833,1.851665929,0.759074365,DB0000710028411_,0.275655529,0.115490047,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,leuprolide,DB00007
,48985,DB00115,10028411,235,18190,98,10374,0.009778536,1.367573873,1.074511501,1.751487594,0.034965152,DB0011510028411_,3.353403376,0.313038274,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,48987,DB00788,10028411,133,9223,50,5011,0.028834568,1.445184618,1.034597567,2.046466164,0.082123373,DB0078810028411_,2.49953261,0.368237077,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,48989,DB06724,10028411,105,7824,29,3890,0.004106693,1.800083793,1.181185665,2.822820638,0.017446973,DB0672410028411_,4.048589125,0.587833215,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,48991,DB00454,10028813,154,1813,34,567,0.074143312,1.416310269,0.958686314,2.144320627,0.168447812,DB0045410028813_,1.781129297,0.348055088,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,meperidine,DB00454
,48992,DB05812,10028813,9,173,237,7716,0.12415775,1.693569306,0.752128779,3.345681167,0.247299394,DB0581210028813_,1.397155557,0.526838317,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,abiraterone,DB05812
,48993,DB06724,10028813,502,7427,154,3765,4.14302104643391e-08,1.652408616,1.370607319,2.001078795,8.14504923003106e-07,DB0672410028813_,14.02068536,0.502233991,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,49001,DB00007,10033371,75,1872,82,4370,4.02412662694073e-06,2.134887299,1.532177692,2.97074548,4.88630768972076e-05,DB0000710033371_,9.92648852,0.758413858,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,leuprolide,DB00007
,49007,DB00115,10036018,74,18351,44,10428,0.847930701,0.955712875,0.648851209,1.42242418,0.923978827,DB0011510036018_,0.079066122,-0.045297751,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,cyanocobalamin,DB00115
,49008,DB00169,10036018,145,38546,63,18112,0.655110168,1.081467175,0.798794271,1.478545263,0.788803058,DB0016910036018_,0.237238599,0.078318614,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,49015,DB00169,10038776,54,38637,18,18157,0.254705392,1.409832114,0.813669903,2.555027316,0.415434285,DB0016910038776_,0.878430836,0.343470629,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,49023,DB00115,10043882,58,18367,30,10442,0.739515066,1.099146186,0.695186805,1.770679028,0.85016024,DB0011510043882_,0.16233043,0.094533684,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,cyanocobalamin,DB00115
,49024,DB00169,10043882,109,38582,39,18136,0.157965284,1.313709399,0.903266667,1.946691473,0.294737711,DB0016910043882_,1.221669435,0.272854738,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,cholecalciferol,DB00169
,49032,DB00115,10044565,257,18168,119,10353,0.066292849,1.230712539,0.985110724,1.544726353,0.154703913,DB0011510044565_,1.866242225,0.207593302,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,49035,DB06724,10044565,81,7848,23,3896,0.016034386,1.748230409,1.086851714,2.916454691,0.051903806,DB0672410044565_,2.95836316,0.558604081,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,49037,DB00454,10047700,145,1822,38,563,0.415638475,1.179004528,0.808550427,1.75477607,0.584853175,DB0045410047700_,0.536394447,0.164670462,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,meperidine,DB00454
,49039,DB06724,10047700,283,7646,104,3815,0.00831571,1.357699409,1.076800298,1.722525033,0.030707844,DB0672410047700_,3.483237165,0.305791656,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,49050,DB00115,10051792,56,18369,27,10445,0.567687745,1.179330418,0.732049682,1.943269047,0.718770346,DB0011510051792_,0.330213379,0.164946835,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,49051,DB00169,10051792,136,38555,55,18120,0.392603679,1.16211428,0.843253767,1.620844533,0.562528629,DB0016910051792_,0.575313251,0.150241001,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,49060,DB00169,10057040,58,38633,23,18152,0.551953597,1.184840354,0.719342819,2.013393334,0.705801382,DB0016910057040_,0.34842141,0.169608043,NA,10057040,Temperature intolerance,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,49074,DB01224,10043118,52,8056,23,5894,0.046203234,1.654055839,0.993259838,2.835073488,0.117890792,DB0122410043118_,2.137996572,0.503230356,NA,10043118,Tardive dyskinesia,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,49079,DB00695,10002198,57,27992,28,20500,0.098742476,1.49084607,0.932276152,2.435410082,0.208944468,DB0069510002198_,1.565686766,0.399343791,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,furosemide,DB00695
,49080,DB00813,10002198,67,10505,44,10124,0.056481175,1.467467278,0.987424498,2.200240336,0.13692485,DB0081310002198_,1.988323042,0.383537975,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,fentanyl,DB00813
,49095,DB00213,10051792,59,18836,33,13388,0.290611984,1.270754716,0.815795673,2.010260965,0.455894243,DB0021310051792_,0.785494419,0.239610988,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,49111,DB00175,10000087,102,8029,53,6053,0.027745259,1.450848154,1.029280158,2.065630812,0.079665029,DB0017510000087_,2.529924569,0.372148319,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,49113,DB00175,10028372,75,8056,57,6049,1,0.987984113,0.689638686,1.422037711,1,DB0017510028372_,0,-0.012088662,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,49114,DB00706,10028372,17,1058,174,15751,0.135618192,1.454475972,0.825043897,2.408487557,0.263614286,DB0070610028372_,1.333268282,0.374645679,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,tamsulosin,DB00706
,49115,DB00999,10028372,189,21241,119,12120,0.405243212,0.906243242,0.715909118,1.150986094,0.574919327,DB0099910028372_,0.553525549,-0.09844753,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,49116,DB01067,10028372,30,4331,28,4795,0.598191768,1.186191392,0.683608546,2.064168027,0.743057613,DB0106710028372_,0.296981696,0.170747663,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,glipizide,DB01067
,49117,DB08899,10028372,7,242,152,7981,0.241277143,1.518666886,0.593988677,3.254534961,0.399405185,DB0889910028372_,0.917778876,0.417832901,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,enzalutamide,DB08899
,49118,DB00706,10046571,76,999,377,15548,3.47843692257032e-15,3.137137129,2.398729006,4.059750418,2.18211729140241e-13,DB0070610046571_,29.15331057,1.143310642,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,tamsulosin,DB00706
,49119,DB08899,10046571,6,243,132,8001,0.306864414,1.496521674,0.534132331,3.392792161,0.473929847,DB0889910046571_,0.746695971,0.403143532,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,enzalutamide,DB08899
,49121,DB00542,10017577,39,1647,19,1405,0.046525378,1.750723195,0.982404093,3.223224293,0.118551651,DB0054210017577_,2.132406538,0.560028957,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,benazepril,DB00542
,49122,DB00989,10017577,22,812,46,832,0.006277175,0.490239728,0.278153261,0.840386197,0.02455291,DB0098910017577_,3.706924917,-0.712860766,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,rivastigmine,DB00989
,49141,DB00472,10047942,69,10690,23,4289,0.488878308,1.203623602,0.740262661,2.025117828,0.652373697,DB0047210047942_,0.427137727,0.185336675,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,fluoxetine,DB00472
,49142,DB00697,10047942,60,6036,13,1793,0.33074526,1.370940527,0.74215081,2.729011669,0.499459934,DB0069710047942_,0.694227895,0.31549702,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,tizanidine,DB00697
,49144,DB00736,10047942,126,10465,62,5491,0.700266612,1.066329091,0.779211121,1.472250686,0.819879108,DB0073610047942_,0.198598379,0.064221994,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,esomeprazole,DB00736
,49145,DB00959,10047942,79,7999,32,4970,0.049280662,1.533854529,1.003604831,2.394687414,0.123642648,DB0095910047942_,2.090359747,0.427783867,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,methylprednisolone,DB00959
,49156,DB00005,10048685,51,128031,26,42393,0.085444955,0.649497174,0.397419905,1.085411487,0.187441215,DB0000510048685_,1.674290004,-0.431556794,NA,10048685,Oral infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,49157,DB00169,10020635,58,38633,59,18116,3.82047245707408e-05,0.46097556,0.31507251,0.674211513,0.000350877,DB0016910020635_,7.955073617,-0.774410253,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,49158,DB00480,10011732,59,67369,56,67606,0.780313841,1.057299863,0.720787738,1.552355506,0.880413337,DB0048010011732_,0.12736378,0.055718359,NA,10011732,Cyst,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,49161,DB05676,10043882,51,47078,33,25296,0.423632645,0.8304184,0.525528259,1.328686408,0.592438832,DB0567610043882_,0.523507648,-0.185825608,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,apremilast,DB05676
,49164,DB06285,10028334,268,8582,18,1088,0.007224599,1.88746987,1.165476543,3.247506154,0.027451909,DB0628510028334_,3.595319581,0.635237239,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,teriparatide,DB06285
,49165,DB06285,10028372,85,8765,9,1097,0.742934005,1.182058225,0.591917248,2.681090485,0.852863708,DB0628510028372_,0.159155524,0.167257177,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,teriparatide,DB06285
,49167,DB08910,10038428,91,16653,119,17369,0.111351772,0.797591306,0.599774575,1.057696421,0.22808279,DB0891010038428_,1.478046602,-0.22615896,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,pomalidomide,DB08910
,49169,DB00688,10023439,42,6448,60,5318,0.00680317,0.577361229,0.379007999,0.8723899,0.026202845,DB0068810023439_,3.641887289,-0.549287161,NA,10023439,Kidney transplant rejection,10021428,Immune system disorders,Immun,mycophenolate mofetil,DB00688
,49170,DB00115,10018836,37,18388,19,10453,0.781953049,1.107027258,0.620139732,2.039012033,0.881222599,DB0011510018836_,0.126445019,0.101678277,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,49178,DB00904,10019022,64,23005,18,14438,0.001975315,2.231426862,1.305458785,4.00240626,0.009634034,DB0090410019022_,4.642453254,0.802641229,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,49181,DB00230,10005557,125,19549,53,8598,0.870520949,1.037278326,0.745750135,1.460213179,0.942596695,DB0023010005557_,0.059116771,0.036600288,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,pregabalin,DB00230
,49182,DB00641,10005557,118,14006,117,12358,0.393609569,0.889882107,0.682350568,1.160585795,0.563539818,DB0064110005557_,0.573517287,-0.116666289,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,simvastatin,DB00641
,49183,DB00814,10005557,62,8225,15,3400,0.060144324,1.708542796,0.958874214,3.238707462,0.143737198,DB0081410005557_,1.939768664,0.535640841,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,meloxicam,DB00814
,49201,DB00230,10052804,31,19643,19,8632,0.281812303,0.716987303,0.392194912,1.344107993,0.445788307,DB0023010052804_,0.807911087,-0.332697147,NA,10052804,Drug tolerance,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,49209,DB00264,10061822,168,29439,128,24764,0.413176274,1.104036549,0.871462153,1.401507529,0.582615788,DB0026410061822_,0.540227335,0.098973053,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,49210,DB00641,10061822,100,14024,85,12390,0.824703126,1.03940123,0.769765903,1.406163903,0.907142323,DB0064110061822_,0.097455925,0.038644807,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,49211,DB00814,10061822,61,8226,11,3404,0.008805946,2.294630576,1.194786783,4.843330468,0.032147818,DB0081410061822_,3.437410688,0.830571861,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,49214,DB00437,10013710,41,6880,94,11452,0.09044039,0.72603268,0.489728107,1.059827638,0.195946724,DB0043710013710_,1.629912472,-0.320160252,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,49215,DB00497,10013710,144,19123,171,16204,0.003106771,0.713576354,0.567106593,0.896842786,0.013922339,DB0049710013710_,4.27426058,-0.337465834,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,49220,DB00343,10022595,42,8694,54,5041,0.000113888,0.450996526,0.293490099,0.688826128,0.000891868,DB0034310022595_,7.022192641,-0.796295642,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,diltiazem,DB00343
,49222,DB00437,10022595,20,6901,51,11495,0.111355771,0.653230359,0.368553815,1.11622272,0.22808279,DB0043710022595_,1.478046602,-0.425825442,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,allopurinol,DB00437
,49223,DB00497,10022595,28,19239,42,16333,0.022020325,0.565984446,0.337698735,0.935282195,0.066674835,DB0049710022595_,2.70792769,-0.569188682,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,oxycodone,DB00497
,49233,DB00682,10037394,31,19428,34,16330,0.319201823,0.766384462,0.455293099,1.285694122,0.487344506,DB0068210037394_,0.718784002,-0.266071327,NA,10037394,Pulmonary haemorrhage,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,49237,DB00335,10003988,173,8293,81,5384,0.016309416,1.386578391,1.056446967,1.832519219,0.052613279,DB0033510003988_,2.94478673,0.326839123,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,49239,DB00254,10023125,33,5902,40,3348,0.001371726,0.468026289,0.285439028,0.762767962,0.007144012,DB0025410023125_,4.941480703,-0.759230812,NA,10023125,Jarisch-Herxheimer reaction,10021428,Immune system disorders,Immun,doxycycline,DB00254
,49246,DB00465,10027599,59,2045,11,872,0.011132108,2.28656285,1.182467526,4.852114762,0.038773928,DB0046510027599_,3.250007211,0.827049751,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,ketorolac,DB00465
,49247,DB01069,10027599,137,6563,8,2387,1.03209442708688e-10,6.227821024,3.066752164,14.73782685,3.3595791970252e-09,DB0106910027599_,19.51145011,1.829026516,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,49250,DB01373,10042674,161,22559,23,7358,6.74467504925998e-05,2.283277442,1.46810325,3.707639494,0.000568947,DB0137310042674_,7.471723847,0.825611885,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,49254,DB05676,10013911,88,47041,41,25288,0.517793575,1.153800533,0.787607859,1.715388091,0.677293064,DB0567610013911_,0.389651214,0.143061305,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,49255,DB08908,10011224,52,10621,23,3256,0.170779302,0.693118006,0.416005672,1.188577173,0.311915642,DB0890810011224_,1.165022507,-0.366555011,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dimethyl fumarate,DB08908
,49256,DB08908,10052904,50,10623,16,3263,0.884537969,0.959886312,0.536721412,1.80841058,0.951918915,DB0890810052904_,0.049275421,-0.040940427,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,dimethyl fumarate,DB08908
,49260,DB00697,10037660,122,5974,45,1761,0.225446077,0.799198279,0.560876954,1.156346507,0.380232743,DB0069710037660_,0.966971732,-0.224146206,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,49268,DB00175,10061024,44,8087,60,6046,0.002709555,0.548288889,0.362360145,0.823896383,0.0124392,DB0017510061024_,4.386902485,-0.600952961,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,pravastatin,DB00175
,49269,DB00341,10061024,44,11361,22,5046,0.68873559,0.888315204,0.52047138,1.557982,0.812391113,DB0034110061024_,0.207773389,-0.11842864,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,cetirizine,DB00341
,49270,DB00678,10061024,92,15507,95,10629,0.005633039,0.663813527,0.492311202,0.894681893,0.02251417,DB0067810061024_,3.79361039,-0.409754002,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,losartan,DB00678
,49271,DB00736,10061024,34,10557,39,5514,0.001150175,0.455361533,0.278502791,0.741265333,0.006186282,DB0073610061024_,5.085420956,-0.786663597,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,esomeprazole,DB00736
,49274,DB00264,10008469,179,29428,127,24765,0.150317592,1.186110905,0.93896312,1.501884196,0.284405104,DB0026410008469_,1.257355635,0.170679808,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,49275,DB00158,10035598,63,16752,43,8061,0.07815891,0.705000325,0.470466452,1.065412104,0.175275741,DB0015810035598_,1.741394885,-0.349557015,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,49282,DB00281,10016825,57,11401,24,5647,0.555343399,1.176329111,0.717521116,1.984277517,0.708750207,DB0028110016825_,0.344252133,0.162398667,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,lidocaine,DB00281
,49285,DB01104,10016825,78,15385,19,7267,0.008517845,1.93904353,1.16171351,3.394069007,0.031320077,DB0110410016825_,3.463495957,0.662194826,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,sertraline,DB01104
,49286,DB00281,10020772,145,11313,87,5584,0.160150688,0.822677428,0.625072678,1.088074652,0.29767428,DB0028110020772_,1.21175541,-0.195191102,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,lidocaine,DB00281
,49287,DB00620,10020772,70,4758,30,3102,0.063255283,1.521150283,0.975996394,2.423221524,0.149399328,DB0062010020772_,1.901132504,0.419466814,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,triamcinolone,DB00620
,49299,DB01104,10027951,62,15401,22,7264,0.291970871,1.329249159,0.804922676,2.272661368,0.457425382,DB0110410027951_,0.782141508,0.284614241,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,49301,DB01281,10011906,159,8773,73,1725,2.21465700115762e-08,0.428310671,0.320975269,0.575934272,4.59812474529447e-07,DB0128110011906_,14.59244709,-0.84790648,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,49302,DB00331,10047340,95,24851,37,20715,4.92356060170698e-05,2.140164261,1.448867206,3.221397045,0.00043589,DB0033110047340_,7.738120258,0.760882584,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,metformin,DB00331
,49304,DB00524,10007559,109,1468,98,1246,0.717792879,0.944090234,0.704272207,1.266816803,0.833360193,DB0052410007559_,0.182289326,-0.057533531,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,metolazone,DB00524
,49308,DB08908,10042458,33,10640,20,3259,0.021687544,0.505393789,0.281110982,0.930847424,0.065925418,DB0890810042458_,2.719231199,-0.682417374,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,dimethyl fumarate,DB08908
,49309,DB00635,10035226,105,32948,148,23646,1.25909376446332e-07,0.509160288,0.392441955,0.658660875,2.24298743469456e-06,DB0063510035226_,13.0077019,-0.674992404,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,49316,DB00512,10013710,68,4669,124,4974,0.000339294,0.584244179,0.426879532,0.793865594,0.002235171,DB0051210013710_,6.10343753,-0.53743627,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,49317,DB00601,10013710,71,834,62,849,0.41824129,1.165657899,0.805858481,1.689681363,0.587242451,DB0060110013710_,0.53231751,0.153285648,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,linezolid,DB00601
,49318,DB00656,10013710,146,11867,185,6434,3.2585381053855e-14,0.427895979,0.341330389,0.535699112,1.78253223933523e-12,DB0065610013710_,27.05298616,-0.848875153,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,49319,DB00813,10013710,93,10479,167,10001,9.36263905329043e-07,0.53150377,0.40729192,0.690055091,1.35218114019637e-05,DB0081310013710_,11.21120652,-0.632044989,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,49320,DB01175,10013710,126,10598,96,4796,0.000187327,0.593974028,0.450773052,0.784706448,0.001365092,DB0117510013710_,6.596533424,-0.520919685,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,49331,DB00512,10035528,61,4676,40,5058,0.015943279,1.649485369,1.086826929,2.528068875,0.051692252,DB0051210035528_,2.962447367,0.500463342,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,vancomycin,DB00512
,49332,DB00813,10035528,99,10473,75,10093,0.127722136,1.27208804,0.931598052,1.743231198,0.252419274,DB0081310035528_,1.376663789,0.240659676,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,fentanyl,DB00813
,49333,DB01175,10035528,83,10641,42,4850,0.563132706,0.900727095,0.613199705,1.340663746,0.715207923,DB0117510035528_,0.335181977,-0.104552959,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,escitalopram,DB01175
,49334,DB00601,10040108,78,827,53,858,0.023223528,1.526499054,1.048442356,2.236627875,0.069410477,DB0060110040108_,2.667717452,0.422976913,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,linezolid,DB00601
,49337,DB00813,10041101,36,10536,14,10154,0.002811403,2.478282884,1.303409258,4.976845507,0.01281723,DB0081310041101_,4.356964935,0.907565935,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,49353,DB08910,10042128,75,16669,35,17453,5.11457898891953e-05,2.243601934,1.482194422,3.455550474,0.000450752,DB0891010042128_,7.704593819,0.808082581,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,49356,DB08910,10061428,141,16603,146,17342,0.95277912,1.008739539,0.793771876,1.281538451,0.990774189,DB0891010061428_,0.009268632,0.00870157,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,pomalidomide,DB08910
,49361,DB05332,10050584,53,976,24,763,0.033822504,1.725894041,1.035967225,2.951887534,0.093023387,DB0533210050584_,2.37490434,0.545745201,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,romiplostim,DB05332
,49367,DB00338,10007632,42,33632,17,22255,0.10945948,1.634824313,0.910644196,3.064024683,0.22527835,DB0033810007632_,1.490418532,0.491535345,NA,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,omeprazole,DB00338
,49369,DB00695,10007632,64,27985,29,20499,0.035134033,1.616531526,1.026772596,2.601703301,0.095689364,DB0069510007632_,2.346648129,0.48028282,NA,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,furosemide,DB00695
,49370,DB00722,10007632,22,25381,37,25995,0.068492778,0.608987694,0.342091116,1.060159066,0.158584688,DB0072210007632_,1.841466519,-0.495957218,NA,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,lisinopril,DB00722
,49371,DB01136,10007632,25,9859,35,11080,0.43860652,0.802756612,0.460215135,1.381176027,0.606921239,DB0113610007632_,0.499356252,-0.219703709,NA,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,carvedilol,DB01136
,49373,DB08877,10011224,54,3235,59,3170,0.570830821,0.89687966,0.606273385,1.324461786,0.721268016,DB0887710011224_,0.326744482,-0.108833584,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ruxolitinib,DB08877
,49375,DB00005,10061664,58,128024,16,42403,0.591712442,1.200635259,0.680845002,2.237907642,0.737973549,DB0000510061664_,0.303847297,0.182850799,NA,10061664,Autoimmune disorder,10021428,Immune system disorders,Immun,etanercept,DB00005
,49376,DB00046,10003239,72,5387,43,4649,0.06001749,1.444974251,0.974778149,2.164689848,0.143486489,DB0004610003239_,1.941514404,0.368091502,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin lispro,DB00046
,49377,DB00813,10003239,152,10420,56,10112,7.48152615061022e-11,2.634118399,1.924274222,3.650083928,2.49400018857057e-09,DB0081310003239_,19.80937791,0.968548552,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fentanyl,DB00813
,49378,DB00956,10003239,181,5633,69,3398,0.001132936,1.582314032,1.188605784,2.126667148,0.006103549,DB0095610003239_,5.098884861,0.458888353,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocodone,DB00956
,49379,DB04854,10003239,20,761,46,1440,0.513320952,0.822809892,0.457513977,1.43102463,0.673302289,DB0485410003239_,0.395560883,-0.195030099,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,febuxostat,DB04854
,49382,DB00158,10066901,63,16752,30,8074,1,1.012146412,0.644897825,1.621127727,1,DB0015810066901_,0,0.012073236,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,49383,DB00563,10066901,1648,44998,393,14955,2.20867775561678e-09,1.393623797,1.245679919,1.562122219,5.71971377402828e-08,DB0056310066901_,16.67676198,0.331907403,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,49385,DB00999,10066901,37,21393,35,12204,0.036541148,0.603104891,0.369284242,0.986642672,0.098650215,DB0099910066901_,2.316174871,-0.505664148,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,49386,DB01076,10066901,37,25710,40,25543,0.733430118,0.919012136,0.571299198,1.474788972,0.845381756,DB0107610066901_,0.167966972,-0.084455951,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,49400,DB00924,10022998,52,10110,17,4234,0.428551728,1.280967006,0.727873548,2.365746804,0.597110108,DB0092410022998_,0.515653748,0.247615266,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,49405,DB00904,10013036,36,23033,15,14441,0.19742682,1.504711727,0.80317254,2.959268141,0.345911476,DB0090410013036_,1.061572386,0.408601336,NA,10013036,Diplopia,10015919,Eye disorders,Eye,ondansetron,DB00904
,49408,DB00327,10016322,80,6058,34,4228,0.016369268,1.642087591,1.084169227,2.535452386,0.052744863,DB0032710016322_,2.942288895,0.495968354,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,49409,DB01104,10016322,311,15152,87,7199,8.06838293578096e-06,1.698377233,1.332614116,2.183450205,9.0188154568149e-05,DB0110410016322_,9.313612464,0.529673226,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,49410,DB00904,10047571,124,22945,48,14408,0.004553061,1.622147858,1.15284009,2.314946065,0.018948259,DB0090410047571_,3.966043208,0.483751109,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,ondansetron,DB00904
,49411,DB01075,10024570,66,19882,41,11056,0.613645777,0.895160829,0.596778795,1.356977663,0.755346973,DB0107510024570_,0.280578069,-0.110751879,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,49431,DB00641,10022116,32,14092,22,12453,0.413764996,1.285357504,0.723601419,2.323032684,0.583106609,DB0064110022116_,0.539385247,0.251036893,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,49433,DB00177,10033371,169,4631,59,2791,0.000281764,1.726197914,1.271117255,2.372175173,0.001918943,DB0017710033371_,6.255980937,0.545921253,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,49436,DB01098,10033371,281,7868,164,7045,1.3787541687116e-05,1.534142208,1.257352312,1.876722479,0.000144012,DB0109810033371_,8.845615763,0.427971403,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,49443,DB00695,10007636,50,27999,54,20474,0.047327051,0.677092016,0.451305229,1.014107554,0.120064813,DB0069510007636_,2.119723574,-0.389948098,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,furosemide,DB00695
,49457,DB00741,10013700,104,3990,25,3149,8.24419108887056e-09,3.282612542,2.09910031,5.317381891,1.8900877694807e-07,DB0074110013700_,15.48147238,1.188639612,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,hydrocortisone,DB00741
,49464,DB01075,10069327,38,19910,21,11076,1,1.006644034,0.57561067,1.806379707,1,DB0107510069327_,0,0.006622059,NA,10069327,Product quality issue,10077536,Product issues,Prod,diphenhydramine,DB01075
,49467,DB00437,10003549,240,6681,388,11158,0.705932449,1.033079756,0.873229908,1.220182496,0.82378896,DB0043710003549_,0.193840899,0.032544395,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,49468,DB01241,10003549,26,917,45,1026,0.090035827,0.646594997,0.379655989,1.080697572,0.195239179,DB0124110003549_,1.633529912,-0.436035151,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,gemfibrozil,DB01241
,49469,DB06186,10003549,31,2178,52,3594,1,0.983738198,0.607389994,1.569497393,1,DB0618610003549_,0,-0.016395477,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ipilimumab,DB06186
,49480,DB00390,10012174,79,4066,48,3253,0.149503215,1.316698315,0.905488592,1.932110851,0.283261876,DB0039010012174_,1.261383451,0.275127326,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,digoxin,DB00390
,49481,DB01098,10012174,98,8051,92,7117,0.714769339,0.941674391,0.699848875,1.267880222,0.830910268,DB0109810012174_,0.185233471,-0.060095721,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,rosuvastatin,DB01098
,49483,DB06186,10012174,69,2140,106,3540,0.635591022,1.076779538,0.779515703,1.479347509,0.77352116,DB0618610012174_,0.256802253,0.073974678,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ipilimumab,DB06186
,49484,DB00331,10021789,167,24779,108,20644,0.044841113,1.288249234,1.004561007,1.657810282,0.115276898,DB0033110021789_,2.160418232,0.253284113,NA,10021789,Infection,10021881,Infections and infestations,Infec,metformin,DB00331
,49485,DB00390,10021789,38,4107,25,3276,0.524797147,1.212415379,0.711394346,2.100265335,0.682936506,DB0039010021789_,0.381353387,0.192614551,NA,10021789,Infection,10021881,Infections and infestations,Infec,digoxin,DB00390
,49486,DB00437,10021789,78,6843,105,11441,0.166968015,1.241971855,0.912989855,1.683495667,0.306755733,DB0043710021789_,1.181703508,0.216700322,NA,10021789,Infection,10021881,Infections and infestations,Infec,allopurinol,DB00437
,49489,DB00115,10049438,43,18382,31,10441,0.333287219,0.787894458,0.484720593,1.29423242,0.502348446,DB0011510049438_,0.688461284,-0.238391135,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,49490,DB00331,10049438,47,24899,32,20720,0.429082701,1.222231616,0.763299304,1.980073511,0.597580671,DB0033110049438_,0.51486599,0.200678381,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,49491,DB00381,10049438,53,29307,49,22838,0.424539723,0.842886906,0.560459353,1.269825728,0.593350893,DB0038110049438_,0.52196933,-0.170922487,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,49492,DB00695,10049438,101,27948,83,20445,0.454943505,0.890187299,0.658843614,1.20557835,0.622514382,DB0069510049438_,0.473988547,-0.11632339,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,49498,DB00068,10016173,109,2125,23,642,0.137943576,1.431580799,0.897639136,2.373699172,0.266841837,DB0006810016173_,1.321099166,0.358779287,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,interferon beta-1b,DB00068
,49500,DB00068,10028245,65,2169,26,639,0.205168683,0.736598385,0.456408515,1.220356189,0.35535443,DB0006810028245_,1.034639592,-0.305712467,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,interferon beta-1b,DB00068
,49501,DB01261,10011078,24,3757,33,3270,0.108961182,0.63304776,0.357209753,1.106630783,0.224490098,DB0126110011078_,1.493923678,-0.457209409,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,sitagliptin,DB01261
,49518,DB01067,10038695,35,4326,37,4786,0.905875351,1.046546315,0.638754048,1.711460846,0.957955166,DB0106710038695_,0.042954302,0.045495519,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glipizide,DB01067
,49522,DB01073,10000081,18,1047,33,1617,0.664515136,0.842482008,0.444158913,1.549656039,0.795807475,DB0107310000081_,0.228397988,-0.171402972,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,fludarabine,DB01073
,49523,DB01212,10000081,38,1981,23,1918,0.09271341,1.599436726,0.924787036,2.82347066,0.199580032,DB0121210000081_,1.611539962,0.469651521,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ceftriaxone,DB01212
,49532,DB00959,10038695,146,7932,154,4848,3.34881032332595e-06,0.579493682,0.45751302,0.733635194,4.1653630201112e-05,DB0095910038695_,10.08612203,-0.54560052,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,49533,DB01073,10038695,36,1029,59,1591,0.831149352,0.943433312,0.600667496,1.463938183,0.911697064,DB0107310038695_,0.09244751,-0.058229599,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fludarabine,DB01073
,49534,DB01212,10038695,56,1963,56,1885,0.848453047,0.960261886,0.647318417,1.424586724,0.924360697,DB0121210038695_,0.078652919,-0.040549234,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ceftriaxone,DB01212
,49555,DB00350,10013709,42,498,16,445,0.00408442,2.34361749,1.26926361,4.53140679,0.017376219,DB0035010013709_,4.052652733,0.851695671,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,minoxidil,DB00350
,49558,DB01012,10013709,104,10528,160,8525,3.68119746309286e-07,0.526359775,0.406484644,0.679144362,5.86781536187967e-06,DB0101210013709_,12.04602816,-0.641770317,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,49559,DB01109,10013709,159,4253,198,4072,0.017278073,0.768881011,0.617244077,0.956543434,0.055095734,DB0110910013709_,2.898682987,-0.262819054,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,49564,DB00575,10017955,32,5212,41,3788,0.017175209,0.567295242,0.345095964,0.925044811,0.054827591,DB0057510017955_,2.903561735,-0.566875403,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,clonidine,DB00575
,49566,DB01012,10017955,20,10612,34,8651,0.008927472,0.479548607,0.261354516,0.858016516,0.032505692,DB0101210017955_,3.426340051,-0.734910019,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,cinacalcet,DB01012
,49567,DB01109,10017955,53,4359,87,4183,0.002093114,0.584638522,0.40631241,0.83440256,0.010100513,DB0110910017955_,4.595169078,-0.536761534,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,heparin,DB01109
,49568,DB01115,10017955,30,3570,21,2247,0.773072779,0.899177988,0.496560675,1.656761593,0.87590922,DB0111510017955_,0.132492823,-0.106274279,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,nifedipine,DB01115
,49571,DB00575,10018884,50,5194,39,3790,0.74780863,0.935507725,0.601788638,1.463744048,0.856719761,DB0057510018884_,0.154644413,-0.066665875,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,clonidine,DB00575
,49573,DB01115,10018884,49,3551,20,2248,0.106495136,1.550889386,0.902213175,2.762126835,0.220846125,DB0111510018884_,1.510289086,0.438828564,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,nifedipine,DB01115
,49583,DB05812,10003549,6,176,184,7769,0.32261043,1.439316263,0.514391907,3.257119438,0.490928915,DB0581210003549_,0.711455937,0.364168184,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,abiraterone,DB05812
,49586,DB00635,10060800,115,32938,126,23668,0.001297909,0.655848993,0.504583408,0.851742069,0.006817651,DB0063510060800_,4.988240234,-0.42182471,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,prednisone,DB00635
,49590,DB00684,10008479,27,2765,34,2314,0.121667856,0.664649527,0.384451818,1.138655201,0.243791978,DB0068410008479_,1.411439968,-0.408495404,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,tobramycin,DB00684
,49591,DB00684,10025482,77,2715,71,2277,0.615594928,0.909565267,0.646911527,1.280391688,0.756984056,DB0068410025482_,0.278413087,-0.094788522,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,tobramycin,DB00684
,49592,DB00684,10035664,142,2650,140,2208,0.176381347,0.845140562,0.65973728,1.082752757,0.319179722,DB0068410035664_,1.142000944,-0.16825232,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,tobramycin,DB00684
,49593,DB00684,10047895,52,2740,37,2311,0.454115052,1.185322429,0.759776932,1.865783551,0.621609457,DB0068410047895_,0.475443266,0.17001483,NA,10047895,Weight decreased,10022891,Investigations,Inv,tobramycin,DB00684
,49595,DB00559,10007815,63,9596,40,3266,0.00295055,0.536103675,0.354324363,0.819567981,0.013318772,DB0055910007815_,4.318580821,-0.623427713,NA,10007815,Catheterisation cardiac,10022891,Investigations,Inv,bosentan,DB00559
,49596,DB00682,10007815,63,19396,18,16346,1.59265142505382e-05,2.949417025,1.723546364,5.295582639,0.000163144,DB0068210007815_,8.720875107,1.081607532,female,10007815,Catheterisation cardiac,10022891,Investigations,Inv,warfarin,DB00682
,49597,DB00367,10013968,57,22743,12,455,1.16216383904588e-08,0.095053476,0.050007971,0.196063206,2.57675887889674e-07,DB0036710013968_,15.17156329,-2.353315643,male,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levonorgestrel,DB00367
,49598,DB00706,10022437,16,1059,252,15673,0.899723411,0.939672605,0.526923289,1.563677262,0.956571579,DB0070610022437_,0.044399659,-0.062223757,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,tamsulosin,DB00706
,49604,DB00758,10013968,449,7851,489,9585,0.092212831,1.120989223,0.98053943,1.281366385,0.198762906,DB0075810013968_,1.615642592,0.114211531,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,49605,DB00381,10015090,211,29149,131,22756,0.042956389,1.257422502,1.005613133,1.577070093,0.111600752,DB0038110015090_,2.192827489,0.229063992,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,49607,DB00758,10015090,122,8178,140,9934,0.661970706,1.058509731,0.821978038,1.361611693,0.793904753,DB0075810015090_,0.230791783,0.056862005,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,49608,DB01076,10015090,140,25607,133,25450,0.716231424,1.046191592,0.81866099,1.337412233,0.832149303,DB0107610015090_,0.183743403,0.045156515,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,49609,DB00381,10042727,79,29281,44,22843,0.083534932,1.400678084,0.956412516,2.074743489,0.18435126,DB0038110042727_,1.690912319,0.336956465,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,49614,DB00722,10061256,17,25386,39,25993,0.004706609,0.446355638,0.236665124,0.807924061,0.019482397,DB0072210061256_,3.938243946,-0.806639249,NA,10061256,Ischaemic stroke,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,49615,DB00758,10061256,21,8279,47,10027,0.019920016,0.541169437,0.307000454,0.924138639,0.061570745,DB0075810061256_,2.787568438,-0.614022857,NA,10061256,Ischaemic stroke,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,49616,DB01221,10013709,49,482,90,506,0.002744895,0.571836407,0.386376279,0.838441054,0.012572896,DB0122110013709_,4.376211907,-0.55890233,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ketamine,DB01221
,49617,DB00381,10038063,94,29266,77,22810,0.757930841,0.951450148,0.696107765,1.303852334,0.86479195,DB0038110038063_,0.145266321,-0.049767986,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,49618,DB00736,10038063,40,10551,20,5533,1,1.048810005,0.598145152,1.895545084,1,DB0073610038063_,0,0.047656193,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,49619,DB01050,10038063,41,18067,25,9346,0.517734404,0.848381256,0.503388314,1.456705205,0.677263695,DB0105010038063_,0.389694576,-0.16442515,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,49620,DB00331,10005554,101,24845,74,20678,0.447009864,1.135931702,0.832793874,1.555582951,0.614783366,DB0033110005554_,0.486485324,0.127453197,NA,10005554,Blood glucose abnormal,10022891,Investigations,Inv,metformin,DB00331
,49624,DB00005,10005555,94,127988,21,42398,0.106146024,1.482769936,0.916349441,2.506657115,0.22041778,DB0000510005555_,1.512230535,0.393911917,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,etanercept,DB00005
,49627,DB01306,10025482,126,4082,83,3783,0.017062899,1.406812458,1.053977953,1.885924817,0.054541932,DB0130610025482_,2.90878547,0.341326477,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,49628,DB00047,10054112,146,9139,115,8403,0.235671658,1.167311171,0.906246504,1.506525066,0.392823458,DB0004710054112_,0.934394985,0.15470296,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,insulin glargine,DB00047
,49629,DB00331,10054112,171,24775,133,20619,0.564026755,1.070054567,0.847413407,1.353559311,0.715893731,DB0033110054112_,0.334223544,0.067709644,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,metformin,DB00331
,49630,DB00381,10054112,323,29037,242,22645,0.669940883,1.040902405,0.877565645,1.235940687,0.799758272,DB0038110054112_,0.223445757,0.040088034,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,amlodipine,DB00381
,49631,DB00722,10054112,176,25227,172,25860,0.667254991,1.048948368,0.844644129,1.302802983,0.797852721,DB0072210054112_,0.225831258,0.047788108,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,lisinopril,DB00722
,49632,DB00999,10054112,126,21304,74,12165,0.882819889,0.972258414,0.723293516,1.314921248,0.951043643,DB0099910054112_,0.050195326,-0.028133652,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,hydrochlorothiazide,DB00999
,49633,DB01076,10054112,222,25525,256,25327,0.107739982,0.860463964,0.715036036,1.034867389,0.222707252,DB0107610054112_,1.50189714,-0.150283542,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,atorvastatin,DB01076
,49634,DB01306,10054112,75,4133,59,3807,0.384227499,1.17089501,0.818913088,1.680842172,0.554270976,DB0130610054112_,0.590101585,0.157768422,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,insulin aspart,DB01306
,49635,DB00433,10012735,635,7021,383,5637,1.94710339113601e-05,1.331111052,1.164976596,1.52249414,0.000195119,DB0043310012735_,8.541902904,0.286013971,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,49636,DB00650,10012735,196,1935,165,1849,0.27041189,1.135048804,0.908774773,1.418933228,0.433110507,DB0065010012735_,0.836762371,0.126675649,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,leucovorin,DB00650
,49637,DB00762,10012735,171,992,178,1191,0.224712572,1.153322394,0.913723185,1.455456222,0.37941673,DB0076210012735_,0.969120125,0.142646815,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,irinotecan,DB00762
,49638,DB00526,10013573,39,1559,41,1853,0.650082969,1.130561623,0.70631176,1.807048849,0.784817124,DB0052610013573_,0.242304551,0.122714521,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,oxaliplatin,DB00526
,49639,DB00544,10013573,41,2394,44,2609,1,1.015501981,0.644642983,1.596733552,1,DB0054410013573_,0,0.015383052,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,fluorouracil,DB00544
,49640,DB00571,10013573,166,4957,63,2546,0.046794945,1.353289915,1.00250636,1.846074058,0.119059638,DB0057110013573_,2.128130753,0.302538602,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,propranolol,DB00571
,49641,DB00650,10013573,50,2081,43,1971,0.675647329,1.101283606,0.714281421,1.704273027,0.803392371,DB0065010013573_,0.218912053,0.096476414,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,leucovorin,DB00650
,49643,DB00433,10054236,42,7614,32,5988,0.907232508,1.03221201,0.635359811,1.691631556,0.958657547,DB0043310054236_,0.042221362,0.031704082,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,49644,DB00497,10054236,77,19190,50,16325,0.153469884,1.310071671,0.905342861,1.910699548,0.288841179,DB0049710054236_,1.241878297,0.270081847,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,oxycodone,DB00497
,49651,DB00904,10054236,139,22930,85,14371,0.890607401,1.024894253,0.776264089,1.3598731,0.954671384,DB0090410054236_,0.046388098,0.02458944,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,ondansetron,DB00904
,49653,DB00108,10019974,111,10083,19,3276,0.00750328,1.897940088,1.157805375,3.276375436,0.028300147,DB0010810019974_,3.564888284,0.640769134,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,natalizumab,DB00108
,49654,DB05382,10013700,524,264,96,141,1.74873135775572e-12,2.912202607,2.139450781,3.976389734,7.54768534295716e-11,DB0538210013700_,23.30719508,1.068909704,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,iodine,DB05382
,49656,DB00043,10042674,58,6355,18,2282,0.695174157,1.157036845,0.670340292,2.091399126,0.816560818,DB0004310042674_,0.202653883,0.145862293,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,49657,DB00959,10042674,76,8002,22,4980,0.001118812,2.149799412,1.320866685,3.634950873,0.006041078,DB0095910042674_,5.109172795,0.765374541,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,49660,DB00215,10007515,134,10969,68,5208,0.650098756,0.935625778,0.692330494,1.274289986,0.784818161,DB0021510007515_,0.242303231,-0.066539693,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,citalopram,DB00215
,49661,DB00215,10037660,175,10928,82,5194,0.946442959,1.014350698,0.774253657,1.33807471,0.984925693,DB0021510037660_,0.015189079,0.014248701,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,49664,DB01076,10052904,154,25593,97,25486,0.000381515,1.580968214,1.217611857,2.061059496,0.002465223,DB0107610052904_,6.005472861,0.458037453,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,49665,DB00227,10011906,75,2392,107,1696,5.11619269222357e-06,0.497059292,0.362507808,0.678697464,6.04672324258528e-05,DB0022710011906_,9.713408952,-0.69904596,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,lovastatin,DB00227
,49669,DB06285,10005396,108,8742,7,1099,0.099119612,1.939499716,0.906581122,4.951675946,0.209509791,DB0628510005396_,1.562984808,0.662430062,NA,10005396,Blood calcium increased,10022891,Investigations,Inv,teriparatide,DB06285
,49673,DB00153,10010305,64,7359,35,3404,0.447761529,0.845855894,0.55052721,1.318949399,0.61555501,DB0015310010305_,0.485230964,-0.167406272,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ergocalciferol,DB00153
,49674,DB01373,10010305,206,22514,69,7312,0.832749884,0.969619505,0.733834154,1.294483933,0.912909484,DB0137310010305_,0.091118545,-0.030851547,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,calcium,DB01373
,49676,DB06285,10016256,452,8398,36,1070,0.006142091,1.599652424,1.130375862,2.327069288,0.024107042,DB0628510016256_,3.725251302,0.469786371,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,49677,DB01373,10016322,358,22362,74,7307,0.000240654,1.580734772,1.225879134,2.061949628,0.001681158,DB0137310016322_,6.38827233,0.457889784,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,49680,DB00243,10008479,64,1190,91,1535,0.617470686,0.907254515,0.642428662,1.274995112,0.758456796,DB0024310008479_,0.276469441,-0.097332256,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ranolazine,DB00243
,49682,DB00526,10029331,95,1503,120,1774,0.671766421,0.934405888,0.69989244,1.244769123,0.800822342,DB0052610029331_,0.222116152,-0.067844366,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,oxaliplatin,DB00526
,49685,DB00264,10005364,39,29568,55,24837,0.012914054,0.595646768,0.384583538,0.914606714,0.043647411,DB0026410005364_,3.13161131,-0.518107458,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,metoprolol,DB00264
,49686,DB00338,10005364,53,33621,49,22223,0.104831588,0.714963129,0.475432282,1.077094793,0.218236564,DB0033810005364_,1.522175647,-0.335524306,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,omeprazole,DB00338
,49688,DB00811,10005364,33,2765,86,4070,0.004625662,0.564870879,0.365063049,0.855726836,0.019210858,DB0081110005364_,3.952279621,-0.571158107,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,ribavirin,DB00811
,49708,DB08932,10020100,120,19323,23,6574,0.009174362,1.774913189,1.128208594,2.909424568,0.033227433,DB0893210020100_,3.404379436,0.573751514,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,49714,DB00619,10051066,29,2870,50,2444,0.002892984,0.493978815,0.300409612,0.798745224,0.01311975,DB0061910051066_,4.333636537,-0.705262647,NA,10051066,Gastrointestinal stromal tumour,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,imatinib,DB00619
,49715,DB00619,10051398,40,2859,69,2425,0.000425849,0.491779058,0.323229792,0.739405271,0.002699489,DB0061910051398_,5.914692762,-0.709725733,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,imatinib,DB00619
,49718,DB00005,10010305,252,127830,86,42333,0.801292945,0.970393134,0.75661372,1.254787091,0.892513722,DB0000510010305_,0.113713391,-0.030053997,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,49719,DB00046,10002034,89,5370,84,4608,0.539406496,0.909187017,0.665309195,1.2433642,0.69521917,DB0004610002034_,0.363528131,-0.095204467,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,insulin lispro,DB00046
,49720,DB00047,10002034,140,9145,135,8383,0.715202091,0.950608227,0.743614589,1.215591528,0.831321421,DB0004710002034_,0.184738771,-0.050653261,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,insulin glargine,DB00047
,49734,DB00264,10003997,34,29573,39,24853,0.196887023,0.73266187,0.448494465,1.191572089,0.345253371,DB0026410003997_,1.063476722,-0.31107098,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,metoprolol,DB00264
,49735,DB00381,10003997,30,29330,38,22849,0.050204701,0.615041107,0.367894671,1.019733525,0.125398448,DB0038110003997_,2.076259027,-0.486066173,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,amlodipine,DB00381
,49748,DB00668,10028334,81,10010,22,4281,0.065780764,1.574576614,0.971443783,2.653728276,0.153754603,DB0066810028334_,1.872397433,0.45398642,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,epinephrine,DB00668
,49749,DB09140,10028334,82,3659,23,1775,0.020319,1.729351642,1.073608898,2.888753588,0.06258877,DB0914010028334_,2.771169405,0.547746565,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,oxygen,DB09140
,49750,DB00196,10012735,270,4813,132,3153,0.007524971,1.339932601,1.078651754,1.67104247,0.02836771,DB0019610012735_,3.56250377,0.292619315,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fluconazole,DB00196
,49751,DB01273,10012735,77,1963,28,1247,0.010868622,1.746667933,1.112748551,2.813578456,0.038047775,DB0127310012735_,3.26891267,0.557709935,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,varenicline,DB01273
,49752,DB09153,10012735,287,7512,173,5526,0.043637449,1.22035047,1.003666051,1.48730911,0.112893144,DB0915310012735_,2.181313539,0.199138088,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,49760,DB00563,10029202,43,46603,20,15328,0.19180785,0.707152135,0.406925325,1.269320264,0.338912969,DB0056310029202_,1.082011933,-0.346509453,NA,10029202,Nervous system disorder,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,49761,DB00956,10012174,70,5744,34,3433,0.359493369,1.230427119,0.803778212,1.916438515,0.529193728,DB0095610012174_,0.636400698,0.20736136,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,hydrocodone,DB00956
,49762,DB00526,10021097,36,1562,36,1858,0.475705914,1.189438181,0.724410843,1.95306885,0.641276506,DB0052610021097_,0.444294548,0.173481079,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,oxaliplatin,DB00526
,49763,DB00544,10021097,41,2394,48,2605,0.749330155,0.929436876,0.595025291,1.446016961,0.857883319,DB0054410021097_,0.153287181,-0.073176386,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,fluorouracil,DB00544
,49764,DB00650,10021097,41,2090,38,1976,1,1.020093494,0.63694882,1.637292897,1,DB0065010021097_,0,0.019894284,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,leucovorin,DB00650
,49765,DB00956,10021097,88,5726,24,3443,0.00036255,2.204568571,1.387385308,3.628915804,0.002362032,DB0095610021097_,6.04823298,0.79053183,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,hydrocodone,DB00956
,49766,DB00497,10037377,166,19101,163,16212,0.201176234,0.864377511,0.691384726,1.080746262,0.35039044,DB0049710037377_,1.048707205,-0.145745671,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,49767,DB00526,10037377,26,1572,45,1849,0.148222888,0.679662265,0.400578164,1.131503331,0.281526022,DB0052610037377_,1.267530397,-0.386159273,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxaliplatin,DB00526
,49768,DB00544,10037377,49,2386,59,2594,0.627342993,0.902939824,0.60270053,1.347463964,0.766802789,DB0054410037377_,0.265525631,-0.102099368,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluorouracil,DB00544
,49769,DB00650,10037377,38,2093,46,1968,0.271131435,0.776800779,0.489527028,1.22617162,0.43390604,DB0065010037377_,0.834927265,-0.252571359,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,leucovorin,DB00650
,49771,DB00005,10038153,55,128027,22,42397,0.431721137,0.827870553,0.496588339,1.42592415,0.600158139,DB0000510038153_,0.510562093,-0.188898474,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,etanercept,DB00005
,49773,DB00005,10063910,75,128007,27,42392,0.731125883,0.91990662,0.5853583,1.486223643,0.843600616,DB0000510063910_,0.1700761,-0.083483114,NA,10063910,Sleep disorder due to a general medical condition,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,49774,DB00668,10019211,693,9398,181,4122,3.47568693314579e-10,1.679240805,1.417669051,1.99706358,1.04554985621878e-08,DB0066810019211_,18.37613782,0.51834179,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,epinephrine,DB00668
,49775,DB01109,10019211,244,4168,111,4159,3.59174311448879e-12,2.193271674,1.737766038,2.782242064,1.47208965232659e-10,DB0110910019211_,22.63916801,0.785394344,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,heparin,DB01109
,49776,DB00668,10033371,240,9851,68,4235,0.00246397,1.51728114,1.151651026,2.021664161,0.011533338,DB0066810033371_,4.462513469,0.416920009,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,49777,DB00668,10037660,257,9834,101,4202,0.520256382,1.087262694,0.857857501,1.386678185,0.679352123,DB0066810037660_,0.386615695,0.083663247,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,49778,DB00668,10000081,74,10017,30,4273,0.914442211,1.052213898,0.678694182,1.669005043,0.961733061,DB0066810000081_,0.039018351,0.050896418,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,epinephrine,DB00668
,49779,DB00814,10000081,106,8181,33,3382,0.188428191,1.327811562,0.888834937,2.031062168,0.334540913,DB0081410000081_,1.094996096,0.283532145,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,49780,DB01109,10000081,85,4327,53,4217,0.012561203,1.56291537,1.093111573,2.252246371,0.042701918,DB0110910000081_,3.153511452,0.446552904,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,heparin,DB01109
,49781,DB01222,10000081,171,9103,64,5341,0.002094449,1.567622622,1.167210245,2.127673955,0.010106029,DB0122210000081_,4.594623086,0.449560218,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,49782,DB01409,10000081,65,5966,35,3931,0.356851692,1.223627914,0.797559068,1.905800465,0.526543545,DB0140910000081_,0.641421244,0.201820146,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,tiotropium,DB01409
,49783,DB00814,10019211,464,7823,113,3302,7.79692883999911e-08,1.733105557,1.402124997,2.156818518,1.44478163242423e-06,DB0081410019211_,13.44755237,0.549914919,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,49784,DB01409,10019211,333,5698,107,3859,5.7569259735583e-12,2.107560571,1.683316099,2.656026748,2.29796202300653e-10,DB0140910019211_,22.19382828,0.745531151,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,tiotropium,DB01409
,49785,DB00814,10037660,117,8170,58,3357,0.241979861,0.828907933,0.598381623,1.159100563,0.400153549,DB0081410037660_,0.915906934,-0.187646188,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,49786,DB01409,10037660,137,5894,71,3895,0.100115346,1.275114252,0.947631961,1.728288125,0.210952893,DB0140910037660_,1.556120424,0.243035784,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,49789,DB00005,10061016,102,127980,38,42381,0.557293996,0.88887178,0.606813634,1.326658325,0.71044122,DB0000510061016_,0.341869065,-0.117802283,NA,10061016,Blood test abnormal,10022891,Investigations,Inv,etanercept,DB00005
,49795,DB00351,10011906,100,566,122,742,0.660597205,1.074501369,0.798003386,1.444480727,0.792831265,DB0035110011906_,0.23214486,0.071856711,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,megestrol acetate,DB00351
,49796,DB01098,10011906,176,7973,261,6948,5.91301730399172e-08,0.587665789,0.481264063,0.716210045,1.12300332251028e-06,DB0109810011906_,13.69950392,-0.531596879,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,49797,DB08889,10011906,149,3016,188,3697,0.822498407,0.971508422,0.773966127,1.217769905,0.905668339,DB0888910011906_,0.099082112,-0.028905341,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,49824,DB01015,10002424,17,9870,52,9329,8.88350823887506e-06,0.30900852,0.167412589,0.543574194,9.7904827697623e-05,DB0101510002424_,9.231514697,-1.17438643,male,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,49827,DB00512,10003239,30,4707,23,5075,0.270057008,1.406266573,0.78854754,2.539067393,0.432700302,DB0051210003239_,0.837709935,0.340938372,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,vancomycin,DB00512
,49828,DB01015,10003239,161,9726,97,9284,0.000338439,1.584319159,1.221852802,2.063185353,0.002230101,DB0101510003239_,6.105708181,0.460154762,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfamethoxazole,DB01015
,49835,DB00512,10010264,87,4650,96,5002,0.88152119,0.974850687,0.71878138,1.320625897,0.95045981,DB0051210010264_,0.050809401,-0.025470961,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,49836,DB01015,10010264,107,9780,95,9286,0.671362073,1.069448769,0.802378826,1.427125999,0.800596683,DB0101510010264_,0.222397976,0.067143347,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,49837,DB01212,10010264,51,1968,24,1917,0.003331877,2.069556991,1.244916486,3.53100002,0.014722886,DB0121210010264_,4.218352107,0.72733457,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ceftriaxone,DB01212
,49838,DB06273,10013709,1002,4093,188,1222,2.44501960099783e-08,1.591148872,1.342154235,1.893395056,5.03268130087924e-07,DB0627310013709_,14.50214275,0.464456316,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,49839,DB00512,10015150,79,4658,57,5041,0.024318546,1.499851632,1.050823657,2.152361805,0.071995606,DB0051210015150_,2.631150193,0.405366191,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,vancomycin,DB00512
,49840,DB01015,10015150,96,9791,67,9314,0.058693235,1.363004725,0.985993679,1.89348752,0.141051582,DB0101510015150_,1.958629627,0.30969162,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,49842,DB06273,10015150,71,5024,14,1396,0.289173125,1.40909751,0.78423404,2.715837862,0.454298712,DB0627310015150_,0.789000342,0.342949435,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,tocilizumab,DB06273
,49843,DB01212,10037087,38,1981,40,1901,0.732059497,0.91166289,0.566407075,1.465128166,0.844325752,DB0121210037087_,0.169216897,-0.092484996,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ceftriaxone,DB01212
,49844,DB06273,10037087,139,4956,15,1395,0.00014383,2.608152107,1.52151877,4.801483828,0.001088245,DB0627310037087_,6.823189167,0.958641966,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,tocilizumab,DB06273
,49845,DB06273,10037660,67,5028,31,1379,0.018946344,0.592819624,0.380055922,0.943120946,0.059208732,DB0627310037660_,2.826686254,-0.522865102,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,49846,DB01015,10046735,145,9742,83,9298,0.000181852,1.66731562,1.262393524,2.214168017,0.001331097,DB0101510046735_,6.62175176,0.51121492,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,49847,DB01212,10046735,41,1978,38,1903,0.909781484,1.038036706,0.648041905,1.666486452,0.959437782,DB0121210046735_,0.04140781,0.037331147,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,ceftriaxone,DB01212
,49848,DB06273,10046735,100,4995,15,1395,0.02213409,1.861655316,1.072130463,3.461610021,0.066938338,DB0627310046735_,2.703983411,0.621466047,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,tocilizumab,DB06273
,49850,DB01015,10047513,61,9826,31,9350,0.004530358,1.872350869,1.194967591,2.988088622,0.018874696,DB0101510047513_,3.969933068,0.62719479,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,sulfamethoxazole,DB01015
,49853,DB00512,10048959,36,4701,22,5076,0.035342622,1.766780551,1.00991373,3.157788321,0.096157833,DB0051210048959_,2.341764345,0.569158993,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,49854,DB01015,10048959,127,9760,106,9275,0.356007836,1.138567576,0.871383194,1.490163342,0.525696805,DB0101510048959_,0.64303065,0.12977096,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,49856,DB06273,10048959,68,5027,21,1389,0.697347259,0.894710397,0.539391322,1.54268006,0.817983029,DB0627310048959_,0.20091369,-0.111255192,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,49857,DB00005,10054106,72,128010,26,42393,0.725923065,0.91707579,0.578306734,1.496776171,0.83949526,DB0000510054106_,0.174954448,-0.08656516,NA,10054106,Joint warmth,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,49862,DB00512,10058080,63,4674,60,5038,0.525564963,1.131756363,0.780103728,1.643395241,0.683569636,DB0051210058080_,0.380426747,0.12377073,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,vancomycin,DB00512
,49863,DB01015,10058080,46,9841,51,9330,0.476591157,0.85513391,0.560728177,1.300958567,0.641992443,DB0101510058080_,0.443178746,-0.156497203,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,49878,DB00285,10022437,241,10710,71,3647,0.323655313,1.155845,0.881105465,1.532347697,0.492091619,DB0028510022437_,0.709090362,0.144831678,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,49881,DB00285,10042458,183,10768,65,3653,0.768420693,0.955107646,0.714036266,1.291242275,0.873007498,DB0028510042458_,0.135811134,-0.045931227,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,49882,DB00451,10042458,192,47079,39,15380,0.005742719,1.608232427,1.134427486,2.332621191,0.022863886,DB0045110042458_,3.778196647,0.475135704,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,49884,DB00451,10042464,57,47214,23,15396,0.366427347,0.808128581,0.489841858,1.374871498,0.536023753,DB0045110042464_,0.623576803,-0.213034098,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,49893,DB00186,10064355,50,16851,36,9972,0.373163712,0.821924915,0.524514628,1.299622302,0.542871828,DB0018610064355_,0.610882032,-0.196106233,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,49894,DB00285,10064355,46,10905,22,3696,0.207619156,0.708683935,0.41711746,1.238795652,0.358406036,DB0028510064355_,1.026088756,-0.344345642,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,49895,DB00921,10064355,30,5815,34,4869,0.257581389,0.738835897,0.43607008,1.246007062,0.418443663,DB0092110064355_,0.871213015,-0.302679444,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,buprenorphine,DB00921
,49902,DB01068,10033664,105,13658,38,6802,0.10831681,1.37611013,0.940045448,2.052973465,0.223530451,DB0106810033664_,1.498207626,0.319260773,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,49903,DB01224,10033664,50,8058,20,5897,0.021113347,1.829465528,1.068354439,3.24816302,0.064526985,DB0122410033664_,2.740671763,0.604023863,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,49905,DB08877,10016322,49,3240,24,3205,0.004524975,2.019391183,1.212095262,3.450006896,0.018856755,DB0887710016322_,3.970884089,0.702796071,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,49907,DB00641,10066152,35,14089,15,12460,0.022285884,2.063439611,1.097486456,4.068809961,0.067261966,DB0064110066152_,2.699160345,0.724374305,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,simvastatin,DB00641
,49913,DB00588,10024264,71,16453,38,8430,0.839588055,0.957330451,0.636222125,1.460704265,0.917802954,DB0058810024264_,0.085772558,-0.043606648,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,49916,DB09153,10024264,33,7766,23,5676,0.893041623,1.048654693,0.596685271,1.872523691,0.955451035,DB0915310024264_,0.045571762,0.047508098,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,49917,DB00588,10040984,67,16457,25,8443,0.186624295,1.37491978,0.856186246,2.273815474,0.33227175,DB0058810040984_,1.10180212,0.318395388,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,49922,DB00588,10041466,44,16480,13,8455,0.092063514,1.736428698,0.917954129,3.516061281,0.198522454,DB0058810041466_,1.616853065,0.551830532,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,49925,DB00668,10043528,39,10052,18,4285,0.773034498,0.923621672,0.515234358,1.717456478,0.875903603,DB0066810043528_,0.132499236,-0.079452737,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,49929,DB00668,10016256,469,9622,135,4168,2.81717750728831e-05,1.504839027,1.235604667,1.842579963,0.000268695,DB0066810016256_,8.221935351,0.408685933,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,49930,DB00051,10023469,100,25631,54,11366,0.255408698,0.821224464,0.583596358,1.166529104,0.416129525,DB0005110023469_,0.876758709,-0.196958804,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,adalimumab,DB00051
,49931,DB00656,10014387,79,11934,63,6556,0.034236934,0.688918335,0.487746366,0.976413087,0.093878344,DB0065610014387_,2.365755551,-0.372632542,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,trazodone,DB00656
,49932,DB01224,10014387,130,7978,70,5847,0.043234495,1.36105191,1.00805313,1.850738742,0.112141087,DB0122410014387_,2.187997496,0.308257864,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,quetiapine,DB01224
,49935,DB08877,10006002,34,3255,23,3206,0.183989946,1.455917795,0.830889229,2.594805627,0.328935604,DB0887710006002_,1.111893279,0.375636489,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ruxolitinib,DB08877
,49937,DB00557,10011224,106,5881,46,3021,0.387544121,1.183674017,0.827389988,1.716608845,0.557568689,DB0055710011224_,0.584169574,0.168623175,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxyzine,DB00557
,49938,DB00437,10013573,201,6720,315,11231,0.489223795,1.06643125,0.886642289,1.280374224,0.652604605,DB0043710013573_,0.426783838,0.064317793,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,49939,DB00557,10013573,192,5795,82,2985,0.173539175,1.206031052,0.922837578,1.587842162,0.315509405,DB0055710013573_,1.153566789,0.187334846,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,49940,DB01005,10013573,64,1031,24,843,0.000945993,2.179544007,1.330867063,3.677629853,0.005260856,DB0100510013573_,5.24746156,0.779115684,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,hydroxyurea,DB01005
,49941,DB01016,10013573,41,1060,38,1190,0.423739864,1.21116795,0.753458963,1.951233617,0.592541487,DB0101610013573_,0.523334388,0.191585142,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,glyburide,DB01016
,49942,DB00331,10013952,102,24844,48,20704,0.000965186,1.77086445,1.244104616,2.551857161,0.005351176,DB0033110013952_,5.230438884,0.571467817,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,49943,DB00341,10013952,53,11352,13,5055,0.060444698,1.815379648,0.975186101,3.633514166,0.144205934,DB0034110013952_,1.936512901,0.596294619,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,49944,DB00437,10013952,30,6891,33,11513,0.116959752,1.518751599,0.893903362,2.571298871,0.236556409,DB0043710013952_,1.441568583,0.417888681,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,49946,DB00588,10013952,139,16385,38,8430,0.000321539,1.881925307,1.304899921,2.772973124,0.002135337,DB0058810013952_,6.149130787,0.632295352,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,49959,DB00316,10039101,311,65163,141,36812,0.030775517,1.246069156,1.017522501,1.532048274,0.086433857,DB0031610039101_,2.448375822,0.219993921,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,49960,DB00437,10039101,40,6881,33,11513,0.003341713,2.028030961,1.24575563,3.321896846,0.01475755,DB0043710039101_,4.216000489,0.707065353,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,49962,DB00682,10039101,141,19318,54,16310,3.3951775135441e-07,2.204434883,1.598986224,3.077981727,5.46492596102307e-06,DB0068210039101_,12.11715998,0.790471187,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,49963,DB00722,10039101,120,25283,78,25954,0.001678129,1.579267424,1.177090299,2.129232364,0.008424296,DB0072210039101_,4.77663539,0.456961084,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,49967,DB00341,10050584,111,11294,21,5047,0.000130998,2.361948918,1.470149597,3.970972845,0.001004017,DB0034110050584_,6.903746354,0.859487091,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,49968,DB00557,10050584,44,5943,16,3051,0.274486589,1.411736336,0.779494394,2.685048486,0.437716435,DB0055710050584_,0.826183987,0.344820391,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxyzine,DB00557
,49969,DB00588,10050584,178,16346,54,8414,0.000475565,1.696714556,1.24333683,2.348139166,0.002963191,DB0058810050584_,5.821488576,0.528693767,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,49972,DB00331,10068319,120,24826,61,20691,0.001616206,1.639534138,1.194228145,2.270947033,0.008164902,DB0033110068319_,4.807910593,0.494412139,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,49973,DB00341,10068319,124,11281,29,5039,0.001088816,1.909877807,1.264421767,2.973077794,0.005910072,DB0034110068319_,5.131097345,0.647039264,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,49974,DB00588,10068319,167,16357,38,8430,1.20650634510697e-06,2.264875702,1.582650735,3.315637136,1.69226356889738e-05,DB0058810068319_,10.98685844,0.81751988,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,49978,DB08877,10028334,77,3212,39,3190,0.000679019,1.960628613,1.312683371,2.970228426,0.00399194,DB0887710028334_,5.523478039,0.673265143,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ruxolitinib,DB08877
,49979,DB08877,10043554,55,3234,64,3165,0.356556982,0.841063038,0.573662565,1.229620243,0.526242168,DB0887710043554_,0.641993776,-0.173088666,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,ruxolitinib,DB08877
,49983,DB00455,10037087,236,9165,80,5038,0.000167319,1.62156427,1.250119882,2.121755278,0.001239392,DB0045510037087_,6.693134167,0.483391282,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,loratadine,DB00455
,49984,DB00480,10037087,1170,66258,830,66832,9.5551275145456e-15,1.421839752,1.298897764,1.556982081,5.64550699632609e-13,DB0048010037087_,28.2027462,0.351951633,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,49985,DB00455,10037844,319,9082,139,4979,0.025374631,1.258171817,1.024479753,1.551568421,0.074322729,DB0045510037844_,2.599338461,0.229659728,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,loratadine,DB00455
,49986,DB00787,10037844,583,16417,536,16712,0.094653994,1.107227662,0.981036891,1.249865227,0.20271981,DB0078710037844_,1.595930498,0.10185929,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,49987,DB00451,10017412,143,47128,43,15376,0.670897068,1.08500367,0.766355686,1.564338557,0.800350804,DB0045110017412_,0.222705143,0.08158337,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,levothyroxine,DB00451
,49988,DB00682,10017412,69,19390,54,16310,0.717581866,1.074830452,0.741434027,1.565209476,0.833158787,DB0068210017412_,0.182531035,0.07216293,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,warfarin,DB00682
,49989,DB08877,10017412,89,3200,69,3160,0.147181553,1.273681626,0.915875431,1.777604671,0.279993277,DB0887710017412_,1.272989687,0.241911624,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,ruxolitinib,DB08877
,50009,DB00165,10016256,194,1951,91,1275,0.013320579,1.393070882,1.069103842,1.825654969,0.044736655,DB0016510016256_,3.106962086,0.331510578,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pyridoxine,DB00165
,50011,DB00316,10017853,126,65348,51,36902,0.049872036,1.395136102,0.999901805,1.971936487,0.124780981,DB0031610017853_,2.081195232,0.332991974,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,50013,DB00722,10017853,56,25347,34,25998,0.015245898,1.689332493,1.083561974,2.669254581,0.049948425,DB0072210017853_,2.996764306,0.524333476,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,50014,DB00736,10017853,39,10552,13,5540,0.187962651,1.575015706,0.822178748,3.218538346,0.334005954,DB0073610017853_,1.09659646,0.454265244,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,50017,DB01050,10017853,74,18034,34,9337,0.611936003,1.12684307,0.740588514,1.746176778,0.753877851,DB0105010017853_,0.282524926,0.11941998,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,50022,DB00316,10030216,52,65422,24,36929,0.474023697,1.222981287,0.740354512,2.074930928,0.63978996,DB0031610030216_,0.446615344,0.201291556,NA,10030216,Oesophagitis,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,50030,DB08904,10003239,386,11224,80,3479,0.000854302,1.495485421,1.168916003,1.933220173,0.00483482,DB0890410003239_,5.331911465,0.40245085,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,certolizumab pegol,DB08904
,50031,DB08904,10042674,90,11520,24,3535,0.581118271,1.150704113,0.725480276,1.891244665,0.729530004,DB0890410042674_,0.315354783,0.140374027,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,50032,DB00007,10000081,55,1892,36,4416,2.82758060442602e-09,3.565042952,2.291451405,5.608390259,7.18096195046744e-08,DB0000710000081_,16.44924739,1.271176102,female,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,leuprolide,DB00007
,50033,DB00736,10000081,179,10412,89,5464,0.697812389,1.055454557,0.812200812,1.379787032,0.818262715,DB0073610000081_,0.200571827,0.053971534,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,50035,DB08899,10000081,7,242,56,8077,0.002513105,4.170592264,1.586903336,9.30234022,0.011708077,DB0889910000081_,4.447476349,1.428058056,female,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,enzalutamide,DB08899
,50036,DB11089,10000081,275,9900,152,8255,5.24472488753475e-05,1.508552787,1.23022729,1.855509346,0.000460139,DB1108910000081_,7.683982308,0.411150772,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,50044,DB08877,10000081,68,3221,71,3158,0.732233932,0.938995922,0.660804149,1.333520111,0.844418874,DB0887710000081_,0.169106611,-0.062944143,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ruxolitinib,DB08877
,50048,DB00451,10061394,106,47165,14,15405,0.000611073,2.473066541,1.410224833,4.678198575,0.003654618,DB0045110061394_,5.611763576,0.905458895,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,50051,DB00471,10002034,143,14046,55,5410,1,1.001423866,0.72769059,1.395127782,1,DB0047110002034_,0,0.001422853,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,montelukast,DB00471
,50052,DB13867,10002034,80,4470,41,2513,0.702521245,1.096958402,0.741199734,1.645229924,0.821576595,DB1386710002034_,0.196530108,0.092541261,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,fluticasone,DB13867
,50064,DB06643,10023469,74,52347,7,7508,0.399114811,1.51622366,0.699975066,3.903514903,0.568988897,DB0664310023469_,0.563894358,0.416222809,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,denosumab,DB06643
,50066,DB00254,10008531,50,5885,36,3352,0.31094167,0.791123294,0.504072993,1.25277194,0.478434807,DB0025410008531_,0.737235322,-0.234301452,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,50067,DB01015,10008531,96,9791,95,9286,0.771696674,0.958393469,0.713055331,1.288342524,0.875048856,DB0101510008531_,0.133475559,-0.042496866,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,50069,DB00115,10006784,117,18308,40,10432,0.004562587,1.66665316,1.153832961,2.45222135,0.01898141,DB0011510006784_,3.964295178,0.51081752,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,50070,DB00203,10006784,47,13831,35,8903,0.571188905,0.864404983,0.545766581,1.380726196,0.721482994,DB0020310006784_,0.326446471,-0.145713889,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,50071,DB00316,10006784,292,65182,112,36841,0.000405125,1.473556899,1.180703359,1.849745343,0.002590614,DB0031610006784_,5.955860474,0.387679137,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,50072,DB00338,10006784,175,33499,62,22210,1.36129690228488e-05,1.871359928,1.392481624,2.543679334,0.00014233,DB0033810006784_,8.857364291,0.626665401,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,50073,DB00425,10006784,57,12638,18,7466,0.022206776,1.870678975,1.084039823,3.380176149,0.067089405,DB0042510006784_,2.70172914,0.626301453,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,50093,DB01222,10003988,172,9102,53,5352,1.9831474090907e-05,1.908156445,1.392135094,2.652827906,0.000198352,DB0122210003988_,8.525464948,0.646137564,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,budesonide,DB01222
,50094,DB00182,10000087,69,5125,23,2829,0.037109572,1.655904027,1.017321135,2.788640172,0.099813261,DB0018210000087_,2.304454227,0.504347099,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,amphetamine,DB00182
,50097,DB00316,10043224,99,65375,37,36916,0.031935477,1.510896264,1.025812448,2.268708853,0.088967796,DB0031610043224_,2.419480819,0.412703027,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,50102,DB00476,10060795,72,17185,15,6162,0.066398255,1.721172574,0.976575067,3.235562118,0.15488114,DB0047610060795_,1.865097295,0.543005788,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,duloxetine,DB00476
,50116,DB01409,10053762,161,5870,91,3875,0.267581834,1.167881797,0.894583736,1.5323723,0.429902862,DB0140910053762_,0.844195998,0.155191678,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tiotropium,DB01409
,50121,DB00169,10009900,58,38633,34,18141,0.314657847,0.801061861,0.515575728,1.262212284,0.482288341,DB0016910009900_,0.729213125,-0.221817105,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,50122,DB00635,10009900,120,32933,107,23687,0.120853247,0.806642222,0.616018524,1.057372531,0.242694445,DB0063510009900_,1.415952053,-0.214875052,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,50131,DB00635,10024690,59,32994,56,23738,0.155603548,0.758019297,0.516662912,1.113263471,0.291570796,DB0063510024690_,1.232472436,-0.277046435,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,prednisone,DB00635
,50155,DB01224,10029354,18,8090,42,5875,1.75919710597143e-05,0.311255982,0.168438879,0.553238225,0.000178328,DB0122410029354_,8.631885022,-1.167139611,male,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,quetiapine,DB01224
,50158,DB01104,10001949,87,15376,46,7240,0.515592153,0.890556516,0.615327114,1.303766059,0.67535455,DB0110410001949_,0.392517467,-0.115908712,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,50161,DB00186,10013786,91,16810,46,9962,0.425339522,1.172390788,0.81288925,1.711269804,0.594114642,DB0018610013786_,0.520682978,0.159045072,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,50162,DB00213,10013786,97,18798,39,13382,0.002194333,1.770548203,1.208373576,2.639622179,0.010491749,DB0021310013786_,4.55716618,0.571289218,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,50163,DB00215,10013786,60,11043,13,5263,0.00797751,2.19956303,1.192812562,4.371957407,0.02972202,DB0021510013786_,3.515867105,0.788258718,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,citalopram,DB00215
,50166,DB00820,10052264,193,11722,38,5778,2.5853083064825e-08,2.503402788,1.757750071,3.650379789,5.29243215232808e-07,DB0082010052264_,14.45181775,0.917650921,NA,10052264,Catheter site erythema,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,50167,DB01240,10052264,445,5306,94,1482,0.016517972,1.322182965,1.047861204,1.682325563,0.053133748,DB0124010052264_,2.934943002,0.279284132,NA,10052264,Catheter site erythema,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,50168,DB06403,10052264,135,21336,32,6629,0.20071335,1.310724182,0.885127384,1.994153373,0.349824931,DB0640310052264_,1.050322448,0.270579795,NA,10052264,Catheter site erythema,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,50169,DB00820,10052268,172,11743,20,5796,5.55773080724879e-13,4.243984959,2.660929289,7.131406749,2.56965618766112e-11,DB0082010052268_,24.38466391,1.445502677,female,10052268,Catheter site pain,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,50170,DB01240,10052268,285,5466,43,1533,8.33890585720492e-05,1.858650019,1.337685892,2.638237472,0.000683255,DB0124010052268_,7.288642705,0.619850428,NA,10052268,Catheter site pain,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,50171,DB06403,10052268,103,21368,13,6648,0.00093707,2.465062063,1.378432494,4.789029218,0.005220065,DB0640310052268_,5.255245383,0.902216985,NA,10052268,Catheter site pain,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,50172,DB00820,10052270,129,11786,16,5800,1.26188929350122e-09,3.96707636,2.349595026,7.155437226,3.44252829057391e-08,DB0082010052270_,17.18447457,1.37802939,female,10052270,Catheter site pruritus,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,50173,DB06403,10052270,84,21387,20,6641,0.354730574,1.304144546,0.792771008,2.244607387,0.524576957,DB0640310052270_,0.645163137,0.265547306,NA,10052270,Catheter site pruritus,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,50174,DB00820,10057688,117,11798,20,5796,1.50710538785841e-06,2.873788212,1.776328268,4.881714298,2.06755037160012e-05,DB0082010057688_,10.78656095,1.055631094,female,10057688,Catheter site discharge,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,50175,DB06403,10057688,76,21395,19,6642,0.468486292,1.241770608,0.742755162,2.176474368,0.634963374,DB0640310057688_,0.454187961,0.216538271,NA,10057688,Catheter site discharge,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,50178,DB00741,10016288,75,4019,63,3111,0.66520375,0.92152655,0.648146432,1.313845787,0.796251221,DB0074110016288_,0.227840538,-0.08172369,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,hydrocortisone,DB00741
,50189,DB01261,10013709,191,3590,173,3130,0.746315683,0.962571201,0.774999378,1.196244607,0.855382202,DB0126110013709_,0.15620689,-0.038147241,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,50199,DB00218,10047513,44,1398,35,915,0.414349863,0.822882887,0.51150507,1.332522745,0.583617938,DB0021810047513_,0.538508727,-0.194941388,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,moxifloxacin,DB00218
,50201,DB00108,10019211,271,9923,49,3246,7.25728702897483e-05,1.809190719,1.326612972,2.512062078,0.000605292,DB0010810019211_,7.409799489,0.592879629,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,50203,DB00586,10000060,42,7067,10,2795,0.166080975,1.661061142,0.818677206,3.717866745,0.305542497,DB0058610000060_,1.185666404,0.50745664,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,diclofenac,DB00586
,50204,DB00586,10053762,260,6849,102,2703,1,1.005986608,0.793403667,1.283271746,1,DB0058610053762_,0,0.00596876,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,diclofenac,DB00586
,50208,DB00761,10017955,229,15078,182,8443,0.000608456,0.704596413,0.57631183,0.86236069,0.00364104,DB0076110017955_,5.615485818,-0.350130104,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,50209,DB01060,10017955,32,8555,35,5046,0.0153565,0.539322807,0.322827407,0.898112202,0.050223416,DB0106010017955_,2.991273913,-0.617440987,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,50210,DB01611,10017955,39,11874,13,2348,0.131085633,0.593256078,0.309412929,1.213209032,0.257344526,DB0161110017955_,1.357339523,-0.522129138,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,50212,DB08935,10037660,29,503,50,763,0.636542288,0.879913807,0.529186522,1.439638406,0.774069583,DB0893510037660_,0.256093509,-0.127931323,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,obinutuzumab,DB08935
,50213,DB01234,10044565,354,31271,239,32649,1.82061194469688e-07,1.546420309,1.307682914,1.831335794,3.11554589624723e-06,DB0123410044565_,12.67910617,0.435942782,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,50216,DB08908,10012378,183,10490,58,3221,0.818471126,0.968809692,0.715339161,1.328845112,0.903170174,DB0890810012378_,0.101844289,-0.031687083,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,dimethyl fumarate,DB08908
,50224,DB00028,10008469,178,13280,51,5564,0.016025831,1.462323661,1.063813362,2.04084183,0.051883679,DB0002810008469_,2.958751001,0.380026719,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,50236,DB01257,10035528,45,891,25,543,0.801005339,1.096920046,0.649898639,1.889415206,0.892358774,DB0125710035528_,0.113887015,0.092506294,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,eculizumab,DB01257
,50242,DB00169,10038435,223,38468,165,18010,1.17022396123696e-05,0.632752625,0.514665038,0.779228417,0.000124582,DB0016910038435_,8.990545091,-0.457675731,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,50243,DB00175,10038435,70,8061,76,6030,0.02858431,0.689019004,0.489893856,0.967910446,0.081574137,DB0017510038435_,2.506243017,-0.372486426,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,pravastatin,DB00175
,50245,DB00758,10038435,79,8221,108,9966,0.460331593,0.886768703,0.653830688,1.198198926,0.62774661,DB0075810038435_,0.465618681,-0.120171094,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,clopidogrel,DB00758
,50246,DB01118,10038435,51,3012,73,4636,0.711468002,1.075304332,0.734538384,1.563896706,0.828039289,DB0111810038435_,0.188694676,0.072603721,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,amiodarone,DB01118
,50256,DB00813,10021576,51,10521,31,10137,0.046173053,1.58507306,0.994131552,2.564998985,0.117836661,DB0081310021576_,2.138455842,0.460630501,NA,10021576,Inadequate analgesia,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,50258,DB00813,10069889,118,10454,74,10094,0.003658364,1.539643137,1.140114302,2.090589996,0.015878485,DB0081310069889_,4.142790244,0.431550661,NA,10069889,Product adhesion issue,10077536,Product issues,Prod,fentanyl,DB00813
,50259,DB00028,10005750,180,13278,80,5535,0.631965124,0.937928352,0.715436644,1.238746315,0.770701819,DB0002810005750_,0.260453725,-0.064081717,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,human immunoglobulin g,DB00028
,50260,DB00193,10005750,148,19172,62,8640,0.654151969,1.075758497,0.793618203,1.473096688,0.788010289,DB0019310005750_,0.238244132,0.073025991,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,tramadol,DB00193
,50261,DB00193,10008531,160,19160,61,8641,0.274689258,1.182909753,0.874520009,1.617779935,0.437933351,DB0019310008531_,0.825688547,0.167977295,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,50262,DB00169,10010305,357,38334,245,17930,5.74835962552521e-06,0.681544313,0.577065134,0.806034778,6.67678447887451e-05,DB0016910010305_,9.614288959,-0.383394008,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,50263,DB00268,10010305,51,2924,45,1500,0.011920787,0.581448371,0.379763101,0.892895412,0.040948496,DB0026810010305_,3.195440199,-0.542233097,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ropinirole,DB00268
,50264,DB00836,10010305,52,5483,75,4000,0.000186488,0.505834666,0.347282945,0.731982758,0.001360296,DB0083610010305_,6.60005288,-0.681545411,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,loperamide,DB00836
,50265,DB01043,10010305,73,1328,103,1307,0.023852415,0.697623459,0.50453911,0.96060977,0.070887424,DB0104310010305_,2.646662243,-0.360075779,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,memantine,DB01043
,50267,DB09053,10010305,18,2267,45,4007,0.236960773,0.707050397,0.384228738,1.249525121,0.394309566,DB0905310010305_,0.930618977,-0.346653333,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ibrutinib,DB09053
,50268,DB09270,10010305,37,3077,34,2334,0.469778434,0.825493226,0.502362569,1.360226119,0.636075111,DB0927010010305_,0.452438623,-0.191774221,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ubidecarenone,DB09270
,50269,DB00268,10017577,96,2879,38,1507,0.165625096,1.322319054,0.894262522,1.98992177,0.304970623,DB0026810017577_,1.187539826,0.279387054,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,50270,DB00836,10017577,78,5457,26,4049,0.000288438,2.225755122,1.408884285,3.622608989,0.001953261,DB0083610017577_,6.238254911,0.800096239,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,50271,DB08880,10017577,129,3209,41,768,0.137523722,0.753060085,0.52107612,1.107899151,0.266264809,DB0888010017577_,1.323263944,-0.28361026,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,teriflunomide,DB08880
,50273,DB09270,10017577,61,3053,37,2331,0.303940311,1.258709101,0.820085443,1.955473956,0.470526596,DB0927010017577_,0.753902794,0.230086673,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,50276,DB00836,10017955,39,5496,42,4033,0.090698129,0.681431186,0.428289333,1.08184183,0.196319046,DB0083610017955_,1.62801416,-0.383560007,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,50279,DB09053,10017955,20,2265,49,4003,0.256839548,0.721394154,0.405111641,1.239878526,0.41772283,DB0905310017955_,0.872937152,-0.326569614,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ibrutinib,DB09053
,50280,DB09270,10017955,19,3095,37,2331,0.00061209,0.386818003,0.209547255,0.692169478,0.003659867,DB0927010017955_,5.610328602,-0.949800973,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ubidecarenone,DB09270
,50281,DB00169,10018836,88,38603,37,18138,0.631530309,1.117498201,0.752712454,1.688910509,0.770380517,DB0016910018836_,0.260870709,0.111092437,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,50291,DB08880,10012735,374,2964,93,716,0.804368963,0.971461939,0.760253108,1.250743425,0.894291439,DB0888010012735_,0.111723563,-0.028953188,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,teriflunomide,DB08880
,50311,DB01229,10045555,30,5711,20,2689,0.227286498,0.706283015,0.387241536,1.314793727,0.382534055,DB0122910045555_,0.960937597,-0.347739251,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,paclitaxel,DB01229
,50312,DB00575,10016256,298,4946,176,3653,0.021872224,1.250513343,1.029190794,1.522990244,0.066325728,DB0057510016256_,2.713177403,0.223554141,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,50313,DB01261,10016256,186,3595,150,3153,0.466833875,1.087496877,0.867498058,1.365130439,0.633425997,DB0126110016256_,0.456612103,0.083878612,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,50317,DB00404,10020646,38,19854,25,9837,0.284699247,0.753147137,0.442676698,1.30248572,0.4492193,DB0040410020646_,0.800244092,-0.283494669,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,alprazolam,DB00404
,50318,DB00575,10020646,25,5219,35,3794,0.012555932,0.519305654,0.297397252,0.894450354,0.042689617,DB0057510020646_,3.153799555,-0.655262641,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,clonidine,DB00575
,50321,DB01136,10020646,69,9815,109,11006,0.028558253,0.709855459,0.516623483,0.969734355,0.081515595,DB0113610020646_,2.506960923,-0.342693908,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,carvedilol,DB01136
,50323,DB01275,10020646,49,3930,38,3311,0.746013069,1.086391876,0.694785334,1.710161843,0.855072649,DB0127510020646_,0.156568844,0.082862,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,hydralazine,DB01275
,50324,DB11089,10020646,40,10135,55,8352,0.017009633,0.599352138,0.388158541,0.91824959,0.054408297,DB1108910020646_,2.91123861,-0.511905977,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,50326,DB08880,10033775,195,3143,31,778,0.024505906,1.556892865,1.052040971,2.373521738,0.072415709,DB0888010033775_,2.625332025,0.442692082,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,teriflunomide,DB08880
,50329,DB00005,10039251,154,127928,7,42412,3.51310694850038e-12,7.293663752,3.455773824,18.44057185,1.44397210541568e-10,DB0000510039251_,22.65845321,1.987005992,female,10039251,Rubber sensitivity,10021428,Immune system disorders,Immun,etanercept,DB00005
,50331,DB06228,10001949,39,15873,25,16051,0.080073468,1.577462091,0.930358323,2.721062828,0.1785259,DB0622810001949_,1.723021588,0.455817284,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,50333,DB01267,10069218,29,2823,56,3659,0.098024926,0.67125517,0.41210602,1.072513949,0.207906493,DB0126710069218_,1.570666853,-0.398605931,NA,10069218,Syringe issue,10077536,Product issues,Prod,paliperidone,DB01267
,50344,DB00410,10012735,98,1507,49,960,0.191285133,1.273938995,0.885951949,1.851868036,0.338191857,DB0041010012735_,1.08414192,0.242113671,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,mupirocin,DB00410
,50345,DB00741,10012735,274,3820,179,2995,0.070252958,1.200106915,0.984215549,1.466131994,0.16172701,DB0074110012735_,1.821845486,0.182410648,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,hydrocortisone,DB00741
,50346,DB00927,10012735,493,7004,245,4771,7.68532918508954e-05,1.370670589,1.16822756,1.611458486,0.000636039,DB0092710012735_,7.360249902,0.315300101,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,50347,DB01047,10012735,66,721,47,433,0.41689046,0.843453958,0.560001691,1.278352963,0.586065824,DB0104710012735_,0.534323168,-0.170249963,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fluocinonide,DB01047
,50348,DB01275,10012735,163,3816,149,3200,0.48593434,0.917377917,0.72632433,1.159383396,0.649960453,DB0127510012735_,0.430843759,-0.086235769,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,hydralazine,DB01275
,50349,DB00186,10028334,228,16673,111,9897,0.090015544,1.219226151,0.966189119,1.546073536,0.195211302,DB0018610028334_,1.633672707,0.198216355,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,50350,DB00335,10028334,154,8312,74,5391,0.039975115,1.349719629,1.0141421,1.809844798,0.105629143,DB0033510028334_,2.247820975,0.299896888,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,50351,DB00390,10028334,44,4101,32,3269,0.728882885,1.096061924,0.67774071,1.790175028,0.841955027,DB0039010028334_,0.172028678,0.091723686,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,digoxin,DB00390
,50354,DB00567,10028334,64,4455,25,2056,0.565932365,1.181407544,0.731124187,1.964078953,0.717429029,DB0056710028334_,0.33208125,0.166706562,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,cephalexin,DB00567
,50355,DB00741,10028334,46,4048,31,3143,0.565760568,1.152087035,0.713111458,1.884257787,0.71728043,DB0074110028334_,0.332288399,0.14157511,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocortisone,DB00741
,50357,DB01275,10028334,38,3941,30,3319,0.808204926,1.066761013,0.64204937,1.787176919,0.896489629,DB0127510028334_,0.109268554,0.064626967,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,hydralazine,DB01275
,50360,DB00635,10021654,41,33012,22,23772,0.307165984,1.342000109,0.780686982,2.366236438,0.474263269,DB0063510021654_,0.745992691,0.294161119,NA,10021654,Increased appetite,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,50362,DB00788,10025482,279,9077,81,4980,1.72958870594262e-07,1.889681344,1.466744254,2.457159109,2.97917687652043e-06,DB0078810025482_,12.72386351,0.636408214,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,50364,DB00958,10020772,115,4479,23,2562,5.91941514183846e-07,2.85965624,1.81032237,4.703084492,8.99634732600311e-06,DB0095810020772_,11.61869192,1.050701422,female,10020772,Hypertension,10047065,Vascular disorders,Vasc,carboplatin,DB00958
,50379,DB09053,10008190,23,2262,48,4004,0.619291596,0.848178805,0.491026988,1.426378384,0.760089634,DB0905310008190_,0.274318914,-0.164663811,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,ibrutinib,DB09053
,50380,DB00829,10067482,52,8000,32,4422,0.648324691,0.898229398,0.566474969,1.444315515,0.783306722,DB0082910067482_,0.244230932,-0.107329789,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,50381,DB00395,10013700,125,2059,18,718,0.000227077,2.420974875,1.457760413,4.249485375,0.0016032,DB0039510013700_,6.435753558,0.8841703,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,carisoprodol,DB00395
,50385,DB00950,10027599,53,4665,9,2047,0.005233679,2.583750806,1.26033088,5.970088474,0.021222963,DB0095010027599_,3.852671507,0.949242144,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,fexofenadine,DB00950
,50387,DB00950,10047700,135,4583,41,2015,0.045802423,1.447632264,1.009401645,2.115136875,0.117101126,DB0095010047700_,2.144717391,0.3699293,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,fexofenadine,DB00950
,50390,DB09038,10013709,51,2197,28,2513,0.001970427,2.083111629,1.283911663,3.443601119,0.009617057,DB0903810013709_,4.64421694,0.733862751,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,empagliflozin,DB09038
,50392,DB00575,10001497,43,5201,62,3767,0.00065449,0.502357142,0.331520312,0.755103225,0.003874171,DB0057510001497_,5.55342349,-0.688443974,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,clonidine,DB00575
,50393,DB01068,10001497,127,13636,97,6743,0.001641658,0.647437028,0.492336902,0.853681331,0.008271225,DB0106810001497_,4.794972644,-0.434733744,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,50394,DB01224,10001497,93,8015,143,5774,1.14201062045138e-08,0.468531903,0.356103843,0.614005927,2.53849887176022e-07,DB0122410001497_,15.18652274,-0.758151083,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,50395,DB00575,10012378,77,5167,47,3782,0.360390877,1.199128676,0.821451067,1.766713259,0.530277328,DB0057510012378_,0.634355148,0.18159519,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,clonidine,DB00575
,50396,DB00575,10013654,33,5211,24,3805,1,1.004005561,0.574580393,1.778388658,1,DB0057510013654_,0,0.00399756,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,clonidine,DB00575
,50397,DB01068,10013654,198,13565,372,6468,1.48652750021228e-56,0.25381425,0.211947696,0.303183576,1.14921692185528e-53,DB0106810013654_,121.8979292,-1.371152577,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,50398,DB01224,10013654,279,7829,204,5713,1,0.998003353,0.827377236,1.205410033,1,DB0122410013654_,0,-0.001998643,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,50405,DB00575,10022523,30,5214,39,3790,0.019533609,0.559194548,0.334782618,0.925465424,0.060692455,DB0057510022523_,2.801935882,-0.581257837,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,clonidine,DB00575
,50406,DB01224,10022523,139,7969,71,5846,0.013654961,1.436150988,1.069145031,1.943473782,0.045643879,DB0122410022523_,3.086885774,0.36196661,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,50414,DB00575,10042458,39,5205,34,3795,0.476271057,0.836348623,0.513348353,1.368580803,0.641659905,DB0057510042458_,0.443696859,-0.17870974,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,clonidine,DB00575
,50415,DB01068,10042458,224,13539,86,6754,0.044733385,1.299367417,1.007085662,1.689123562,0.115065625,DB0106810042458_,2.16225266,0.261877544,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,50416,DB01224,10042458,133,7975,64,5853,0.00567074,1.525128314,1.121341226,2.092747384,0.022620629,DB0122410042458_,3.788892981,0.422078547,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,50428,DB00641,10020646,56,14068,56,12419,0.569385729,0.8827886,0.598003736,1.303209097,0.720261201,DB0064110020646_,0.328141353,-0.124669518,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,simvastatin,DB00641
,50429,DB00471,10020772,183,14006,45,5420,0.005830886,1.573725107,1.128440348,2.235327382,0.023139556,DB0047110020772_,3.766211731,0.453445489,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,montelukast,DB00471
,50430,DB00542,10020772,45,1641,20,1404,0.016329969,1.924656143,1.107278784,3.458051315,0.052666655,DB0054210020772_,2.943772758,0.654747325,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,benazepril,DB00542
,50431,DB01275,10020772,129,3850,108,3241,1,1.005504458,0.769145523,1.316536719,1,DB0127510020772_,0,0.005489364,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,hydralazine,DB01275
,50432,DB00564,10028813,99,2505,44,1419,0.214200776,1.274445278,0.879165868,1.873204616,0.366514445,DB0056410028813_,1.003717345,0.242511008,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,carbamazepine,DB00564
,50433,DB01241,10028813,62,881,45,1026,0.021681054,1.604142646,1.063134136,2.436588602,0.065913314,DB0124110028813_,2.719414829,0.472589437,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,gemfibrozil,DB01241
,50436,DB00564,10047700,71,2533,29,1434,0.169873346,1.385929325,0.883289341,2.225842812,0.31074681,DB0056410047700_,1.168776815,0.326370908,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,carbamazepine,DB00564
,50437,DB01241,10047700,35,908,19,1052,0.008315399,2.13347137,1.177948075,3.977939348,0.030707844,DB0124110047700_,3.483237165,0.757750404,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,gemfibrozil,DB01241
,50441,DB01098,10013911,47,8102,40,7169,0.914372442,1.039696396,0.666578034,1.628649181,0.961698163,DB0109810013911_,0.039054638,0.038928744,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,50442,DB01373,10013911,143,22577,58,7323,0.161768137,0.799708402,0.584775457,1.105975363,0.299758582,DB0137310013911_,1.204777856,-0.223508116,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,calcium,DB01373
,50443,DB13961,10013911,65,9392,53,6361,0.346565107,0.830639727,0.568158742,1.219132909,0.516014605,DB1396110013911_,0.661620209,-0.18555912,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,50444,DB00722,10062060,43,25360,41,25991,0.744772141,1.07484275,0.683977077,1.691345457,0.854246317,DB0072210062060_,0.157535699,0.072174372,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,50449,DB00331,10000381,26,24920,56,20696,3.24377135090485e-05,0.38559479,0.23230659,0.624641444,0.000304129,DB0033110000381_,8.098059017,-0.952968227,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,50450,DB00451,10000381,40,47231,31,15388,0.000458975,0.420395619,0.256388873,0.695321057,0.002875155,DB0045110000381_,5.851648659,-0.866559061,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,50457,DB00222,10038435,39,3167,42,3086,0.65685281,0.904837777,0.568155421,1.437985909,0.790213561,DB0022210038435_,0.235452039,-0.099999604,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,glimepiride,DB00222
,50458,DB00476,10038435,85,17172,38,6139,0.259369242,0.799665028,0.538787438,1.206621922,0.42048292,DB0047610038435_,0.866351418,-0.223562354,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,duloxetine,DB00476
,50460,DB00761,10038435,179,15128,96,8529,0.752181707,1.051233046,0.814617815,1.363447817,0.860304861,DB0076110038435_,0.150468462,0.049963805,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,potassium chloride,DB00761
,50461,DB01098,10038435,87,8062,92,7117,0.258472013,0.834817825,0.614346462,1.133595625,0.419495346,DB0109810038435_,0.868702848,-0.180541752,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,rosuvastatin,DB01098
,50464,DB00331,10021113,57,24889,45,20707,0.842466998,1.053844714,0.700076457,1.594833307,0.919801687,DB0033110021113_,0.08359719,0.052445109,NA,10021113,Hypothermia,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,50465,DB00331,10038540,47,24899,76,20676,0.000363964,0.513547561,0.348966953,0.748849712,0.002369481,DB0033110038540_,6.045084197,-0.666412633,NA,10038540,Renal tubular necrosis,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,50467,DB00555,10048959,52,6995,26,3460,1,0.989275315,0.605359056,1.653569188,1,DB0055510048959_,0,-0.010782609,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,50482,DB00012,10008479,33,1613,18,1295,0.203119956,1.471705766,0.8006602,2.789727621,0.352759038,DB0001210008479_,1.041970067,0.386422113,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,darbepoetin alfa,DB00012
,50484,DB00433,10008479,99,7557,85,5935,0.550769025,0.914725285,0.676195618,1.239620364,0.704818102,DB0043310008479_,0.349815521,-0.089131494,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,50485,DB00351,10013968,47,619,44,820,0.126629796,1.414692422,0.90475866,2.215711141,0.250958622,DB0035110013968_,1.382467208,0.346912138,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,megestrol acetate,DB00351
,50493,DB00012,10028813,154,1492,74,1239,0.000169045,1.727875759,1.287112275,2.336311009,0.001250769,DB0001210028813_,6.683996816,0.546892769,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,darbepoetin alfa,DB00012
,50494,DB00112,10047895,167,5766,117,3974,0.902614874,0.983744878,0.769269563,1.261406705,0.957195726,DB0011210047895_,0.043747388,-0.016388686,NA,10047895,Weight decreased,10022891,Investigations,Inv,bevacizumab,DB00112
,50495,DB00351,10047895,41,625,55,809,0.915528088,0.964933587,0.619016146,1.494073062,0.962157407,DB0035110047895_,0.038577217,-0.035696002,NA,10047895,Weight decreased,10022891,Investigations,Inv,megestrol acetate,DB00351
,50496,DB00012,10061428,74,1572,55,1258,0.717591089,1.076702758,0.743011187,1.568097135,0.833158787,DB0001210061428_,0.182531035,0.073903369,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,darbepoetin alfa,DB00012
,50497,DB00351,10061428,62,604,68,796,0.355190896,1.201446218,0.82352858,1.750284362,0.52496647,DB0035110061428_,0.644420885,0.183526013,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,megestrol acetate,DB00351
,50499,DB00222,10000087,39,3167,18,3110,0.007496201,2.127418541,1.185375625,3.96012405,0.028281561,DB0022210000087_,3.565545234,0.754909292,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,glimepiride,DB00222
,50508,DB01229,10007882,48,5693,29,2680,0.326228158,0.779230186,0.480273576,1.284585041,0.494738742,DB0122910007882_,0.703725449,-0.249448788,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,paclitaxel,DB01229
,50515,DB01006,10012735,481,5466,8,169,0.090914532,1.858820821,0.914416456,4.402688623,0.196685335,DB0100610012735_,1.626150114,0.619942319,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,letrozole,DB01006
,50518,DB00331,10024774,55,24891,52,20700,0.559981836,0.879607895,0.590726443,1.311311015,0.712635143,DB0033110024774_,0.338785711,-0.128279045,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,metformin,DB00331
,50524,DB00222,10028372,32,3174,23,3105,0.280531963,1.360988236,0.769959011,2.441559111,0.444377777,DB0022210028372_,0.81108023,0.30821108,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,glimepiride,DB00222
,50525,DB00331,10028372,166,24780,156,20596,0.286029677,0.884436669,0.705917137,1.108547633,0.450736814,DB0033110028372_,0.796871671,-0.122804369,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,50529,DB01229,10028372,76,5665,16,2693,0.002225311,2.257848425,1.301832907,4.157298786,0.010612774,DB0122910028372_,4.545696933,0.814412335,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,paclitaxel,DB01229
,50530,DB00222,10029331,39,3167,29,3099,0.27489591,1.315891776,0.790828453,2.212444858,0.438128036,DB0022210029331_,0.825244092,0.274514592,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,glimepiride,DB00222
,50531,DB00331,10029331,232,24714,194,20558,0.961049781,0.994772979,0.817771739,1.211162893,0.998584556,DB0033110029331_,0.001416447,-0.005240729,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,metformin,DB00331
,50549,DB01006,10019211,255,5692,7,170,1,1.08798047,0.509253085,2.775791478,1,DB0100610019211_,0,0.084323198,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,letrozole,DB01006
,50558,DB01006,10037844,175,5772,6,171,0.651317961,0.864108055,0.381245868,2.420646109,0.785766952,DB0100610037844_,0.241095029,-0.146057454,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,letrozole,DB01006
,50575,DB00112,10022694,32,5901,20,4071,0.778691378,1.103825652,0.61124276,2.039524399,0.879365569,DB0011210022694_,0.128554576,0.098782012,NA,10022694,Intestinal perforation,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,50586,DB00112,10051398,67,5866,48,4043,0.849069298,0.962024343,0.652731961,1.42739076,0.924859579,DB0011210051398_,0.07811336,-0.038715524,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,bevacizumab,DB00112
,50588,DB00335,10003239,219,8247,101,5364,0.004489641,1.410278724,1.106160504,1.808163524,0.01874219,DB0033510003239_,3.976978129,0.343787361,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,50591,DB00335,10003246,67,8399,15,5450,5.755711946832e-05,2.898149727,1.636139925,5.469856953,0.000497805,DB0033510003246_,7.60530275,1.064072508,female,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,50594,DB00695,10003246,177,27872,55,20473,4.4424437021948e-09,2.363806946,1.736645806,3.262177687,1.07920178107385e-07,DB0069510003246_,16.04187397,0.860273432,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,50595,DB00316,10007882,359,65115,242,36711,0.033189706,0.836372147,0.708202425,0.989075832,0.091700364,DB0031610007882_,2.389228933,-0.178681613,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,50596,DB00335,10007882,42,8424,30,5435,0.716984139,0.903260812,0.551310928,1.496557461,0.832711563,DB0033510007882_,0.18306796,-0.101743939,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,atenolol,DB00335
,50597,DB00425,10007882,63,12632,45,7439,0.319937019,0.824478705,0.552883475,1.238350495,0.488104042,DB0042510007882_,0.717226696,-0.193003965,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,zolpidem,DB00425
,50600,DB00335,10008531,75,8391,37,5428,0.206420964,1.311225121,0.871778908,2.003190151,0.356974966,DB0033510008531_,1.030089623,0.270961907,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,50601,DB00425,10008531,130,12565,56,7428,0.04767818,1.372328739,0.994426245,1.91501942,0.120722567,DB0042510008531_,2.114260199,0.316509106,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,50604,DB00722,10008531,172,25231,135,25897,0.021887659,1.307693472,1.037035129,1.651864974,0.066364877,DB0072210008531_,2.712587321,0.268264877,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,50608,DB00335,10017885,63,8403,23,5442,0.019532287,1.773860878,1.083391036,3.000951678,0.060692455,DB0033510017885_,2.801935882,0.573158458,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,50611,DB00695,10017885,248,27801,81,20447,2.45344301029111e-11,2.251772862,1.744289967,2.932830747,8.79791944413396e-10,DB0069510017885_,20.85133566,0.811717845,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,50612,DB00722,10017885,168,25235,98,25934,6.50099450655933e-06,1.761739239,1.364298416,2.285344471,7.44244950369825e-05,DB0072210017885_,9.505725436,0.566301525,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,50614,DB00316,10019744,29,65445,40,36913,0.000233261,0.408923242,0.244439971,0.67640471,0.001638062,DB0031610019744_,6.414241381,-0.894227814,NA,10019744,Hepatitis C,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,50619,DB00695,10019744,21,28028,44,20484,4.2663297965475e-05,0.348817087,0.19692367,0.599506301,0.000385694,DB0069510019744_,7.860466711,-1.0532076,male,10019744,Hepatitis C,10021881,Infections and infestations,Infec,furosemide,DB00695
,50623,DB00073,10022437,41,7365,42,6365,0.442328209,0.843658177,0.534263666,1.331245913,0.610432204,DB0007310022437_,0.493588041,-0.17000787,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,rituximab,DB00073
,50629,DB00425,10029410,40,12655,24,7460,1,0.982477452,0.577451588,1.705196783,1,DB0042510029410_,0,-0.017677885,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,zolpidem,DB00425
,50632,DB00722,10029410,58,25345,34,25998,0.009015733,1.749802643,1.126253818,2.757322054,0.032765786,DB0072210029410_,3.418370415,0.559503006,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,50649,DB00695,10043882,87,27962,27,20501,3.86948604100371e-05,2.362384487,1.518076754,3.787146556,0.000354803,DB0069510043882_,7.943948352,0.859671485,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,furosemide,DB00695
,50650,DB00722,10043882,64,25339,45,25987,0.055138578,1.45857446,0.980338156,2.186442414,0.13457612,DB0072210043882_,2.005625294,0.377459562,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,lisinopril,DB00722
,50667,DB00904,10055798,79,22990,65,14391,0.103810909,0.760811101,0.540607099,1.073914962,0.216724495,DB0090410055798_,1.529128341,-0.273370176,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,ondansetron,DB00904
,50669,DB00741,10013786,44,4050,26,3148,0.278791692,1.315353744,0.790210311,2.230508422,0.442634752,DB0074110013786_,0.815010337,0.274105636,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocortisone,DB00741
,50670,DB00996,10013786,161,38792,64,22361,0.012365184,1.450081368,1.078468338,1.969811983,0.042158228,DB0099610013786_,3.166325396,0.371619671,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,50672,DB00741,10015150,63,4031,27,3147,0.009908313,1.821476362,1.140307677,2.981929593,0.035289975,DB0074110015150_,3.344156347,0.59964736,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocortisone,DB00741
,50673,DB00996,10015150,255,38698,110,22315,0.01040424,1.33676129,1.064171309,1.688362206,0.036732767,DB0099610015150_,3.304086081,0.290249741,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,50680,DB00169,10003983,77,38614,28,18147,0.294673341,1.292337776,0.828448268,2.070170288,0.460547554,DB0016910003983_,0.775339163,0.256452808,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,50682,DB00399,10006002,194,6798,46,4952,1.21990297644193e-13,3.071847203,2.212382132,4.343602834,6.15900215080741e-12,DB0039910006002_,25.81310634,1.122279076,female,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,50686,DB00169,10046543,127,38564,50,18125,0.33261332,1.193775157,0.853786853,1.691740565,0.501577185,DB0016910046543_,0.689997775,0.177120687,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,50687,DB00169,10062189,80,38611,28,18147,0.214845434,1.342883764,0.863105983,2.146289953,0.367238643,DB0016910062189_,1.001743388,0.294819365,NA,10062189,Vitamin D decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,50690,DB00112,10005483,32,5901,28,4063,0.359422942,0.786915618,0.458169148,1.358785282,0.529149324,DB0011210005483_,0.63648461,-0.239634256,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,bevacizumab,DB00112
,50693,DB01041,10013968,60,2985,82,3036,0.089678916,0.744246864,0.522270511,1.055409455,0.194706175,DB0104110013968_,1.636263654,-0.295382493,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,thalidomide,DB01041
,50697,DB00441,10035598,69,2205,41,1853,0.098601743,1.414150945,0.942127935,2.146226462,0.208784534,DB0044110035598_,1.566452495,0.346529312,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gemcitabine,DB00441
,50698,DB00398,10013968,26,701,62,1476,0.642914982,0.883031736,0.53114572,1.431154297,0.779283743,DB0039810013968_,0.249380059,-0.124394138,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sorafenib,DB00398
,50700,DB00398,10061818,21,706,37,1501,0.480185715,1.206557667,0.665786991,2.133806107,0.645015723,DB0039810061818_,0.438480585,0.187771402,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,sorafenib,DB00398
,50701,DB00112,10000087,50,5883,32,4059,0.821714978,1.078059653,0.6768404,1.73965492,0.905058903,DB0011210000087_,0.099755251,0.075162808,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,50703,DB01101,10000087,104,7485,41,3867,0.158185237,1.310482726,0.902680664,1.934021874,0.295022454,DB0110110000087_,1.220703811,0.270395562,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,50705,DB01259,10011906,162,1107,11,63,0.592113983,0.838270247,0.42659285,1.802000079,0.738386756,DB0125910011906_,0.303287532,-0.17641474,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,lapatinib,DB01259
,50707,DB00072,10059282,44,3679,7,328,0.191163732,0.560502626,0.247806211,1.486812341,0.338047545,DB0007210059282_,1.084568729,-0.578921352,NA,10059282,Metastases to central nervous system,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,trastuzumab,DB00072
,50712,DB00441,10061822,33,2241,23,1871,0.589416288,1.19784089,0.679726773,2.144645387,0.736206692,DB0044110061822_,0.306244368,0.180520678,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,gemcitabine,DB00441
,50713,DB01229,10061822,46,5695,7,2702,0.002744436,3.117497881,1.395528598,8.193867823,0.012571887,DB0122910061822_,4.376292138,1.137030719,female,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,50740,DB00073,10016825,61,7345,56,6351,0.780382252,0.941904967,0.643456368,1.381019112,0.880415616,DB0007310016825_,0.127361192,-0.059850894,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,rituximab,DB00073
,50748,DB00099,10037844,55,2330,39,1916,0.530062505,1.159638946,0.751849395,1.803775491,0.687176433,DB0009910037844_,0.375164204,0.148108703,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,filgrastim,DB00099
,50757,DB00316,10027091,205,65269,111,36842,0.76934758,1.042480592,0.823194735,1.325975894,0.873665614,DB0031610027091_,0.135057569,0.041603058,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,50762,DB00635,10018838,79,32974,44,23750,0.200048324,1.293195587,0.883078509,1.91537338,0.349062016,DB0063510018838_,1.052505677,0.257116355,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,prednisone,DB00635
,50764,DB00635,10023126,29,33024,37,23757,0.024014095,0.563861861,0.334327635,0.942450489,0.07127892,DB0063510023126_,2.641154641,-0.572945984,NA,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,prednisone,DB00635
,50767,DB00073,10042772,39,7367,41,6366,0.431554305,0.821985543,0.515708973,1.308309934,0.599989682,DB0007310042772_,0.510842821,-0.196032472,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,rituximab,DB00073
,50768,DB00285,10007559,62,10889,15,3703,0.292894089,1.405556491,0.78902793,2.664017432,0.458475532,DB0028510007559_,0.779848354,0.340433304,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,venlafaxine,DB00285
,50769,DB00482,10007559,38,8221,18,3053,0.450725345,0.784000638,0.435811213,1.461725127,0.618400444,DB0048210007559_,0.480619064,-0.243345445,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,celecoxib,DB00482
,50771,DB01068,10007559,45,13718,27,6813,0.452957836,0.827766641,0.502137363,1.388681626,0.620556485,DB0106810007559_,0.477138648,-0.189023998,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,clonazepam,DB01068
,50778,DB00482,10038435,40,8219,28,3043,0.013044242,0.52897627,0.317668002,0.891972847,0.044005377,DB0048210038435_,3.123443459,-0.636811707,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,celecoxib,DB00482
,50780,DB00736,10038435,251,10340,172,5381,0.006937257,0.759467824,0.621227548,0.93015905,0.026612056,DB0073610038435_,3.62639093,-0.275137322,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,esomeprazole,DB00736
,50782,DB01068,10038435,64,13699,34,6806,0.747921523,0.93520341,0.607025182,1.46378899,0.856774411,DB0106810038435_,0.154580626,-0.066991223,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,clonazepam,DB01068
,50792,DB00112,10001760,89,5844,35,4056,0.004219272,1.764758885,1.178440586,2.6951893,0.017835891,DB0011210001760_,4.026542515,0.568014072,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,bevacizumab,DB00112
,50793,DB01101,10001760,85,7504,18,3890,0.000229411,2.447792665,1.457154348,4.333090159,0.001617077,DB0110110001760_,6.427135249,0.895186665,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,capecitabine,DB01101
,50795,DB00112,10013952,38,5895,34,4057,0.280163657,0.769206173,0.470550047,1.261956925,0.444006645,DB0011210013952_,0.811915751,-0.26239624,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bevacizumab,DB00112
,50799,DB00019,10016288,186,18826,167,9362,5.59967934156114e-08,0.553854193,0.446316524,0.687759034,1.07123414478118e-06,DB0001910016288_,13.74669917,-0.590853817,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,pegfilgrastim,DB00019
,50800,DB00019,10040047,48,18964,45,9484,0.002813529,0.533436094,0.347450825,0.820354492,0.012824696,DB0001910040047_,4.356382625,-0.628416002,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,pegfilgrastim,DB00019
,50801,DB00541,10040047,186,2948,237,4060,0.447325349,1.080832337,0.881889715,1.323188326,0.615100144,DB0054110040047_,0.485970189,0.077731426,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,vincristine,DB00541
,50802,DB00997,10040047,139,5192,154,3360,6.49462486185523e-06,0.584172202,0.45910365,0.742723068,7.43839714570216e-05,DB0099710040047_,9.506270077,-0.537559473,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,doxorubicin,DB00997
,50804,DB00073,10010774,86,7320,77,6330,0.874525639,0.965819632,0.700471783,1.333679094,0.945651902,DB0007310010774_,0.055880746,-0.034778178,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,rituximab,DB00073
,50805,DB00099,10010774,76,2309,35,1920,0.003668622,1.805366246,1.188619829,2.789964966,0.015918142,DB0009910010774_,4.140295791,0.590763478,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,filgrastim,DB00099
,50810,DB01073,10029354,59,1006,97,1553,0.736169111,0.938986877,0.66092363,1.324843339,0.847633663,DB0107310029354_,0.165306737,-0.062953775,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,fludarabine,DB01073
,50811,DB01137,10029354,106,7666,125,5468,0.000158212,0.604898767,0.461373225,0.791847244,0.001180749,DB0113710029354_,6.741606426,-0.502694162,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,levofloxacin,DB01137
,50812,DB00073,10035664,174,7232,211,6196,0.000889795,0.706536577,0.572988899,0.8703138,0.005004979,DB0007310035664_,5.297322151,-0.347380306,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,rituximab,DB00073
,50814,DB00073,10051055,33,7373,41,6366,0.129172384,0.694972697,0.425200087,1.128055625,0.25443412,DB0007310051055_,1.368713336,-0.36388272,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,rituximab,DB00073
,50818,DB01075,10051055,66,19882,58,11039,0.011257687,0.631790501,0.436883991,0.915871206,0.039126321,DB0107510051055_,3.24095988,-0.459197426,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,diphenhydramine,DB01075
,50828,DB01068,10002034,125,13638,49,6791,0.169572279,1.270211563,0.904752151,1.808087778,0.31034726,DB0106810002034_,1.170063415,0.239183471,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,clonazepam,DB01068
,50829,DB00390,10008479,145,4000,60,3241,8.66695165917691e-06,1.957907533,1.434116819,2.70120007,9.58598040654176e-05,DB0039010008479_,9.252623808,0.671876318,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,50830,DB00390,10053762,89,4056,66,3235,0.68348717,1.075540555,0.770713953,1.507283284,0.80867214,DB0039010053762_,0.21236171,0.072823377,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,digoxin,DB00390
,50831,DB00761,10053762,321,14986,170,8455,0.53707341,1.065332793,0.880080386,1.293173162,0.693252585,DB0076110053762_,0.366360866,0.063287232,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,50844,DB00316,10008118,41,65433,26,36927,0.702866472,0.889938098,0.531407736,1.515548804,0.821706817,DB0031610008118_,0.196371618,-0.116603371,NA,10008118,Cerebral infarction,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,50859,DB00443,10013968,62,2084,28,1162,0.375070911,1.234608024,0.773178235,2.015964281,0.544892439,DB0044310013968_,0.607166863,0.21075353,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,betamethasone,DB00443
,50860,DB00656,10013968,437,11576,199,6420,0.022855222,1.21782327,1.024614662,1.451551766,0.068555234,DB0065610013968_,2.680115527,0.19706506,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,50862,DB00669,10013968,120,6257,28,1069,0.157927175,0.732243522,0.479188852,1.154021494,0.294687523,DB0066910013968_,1.22183973,-0.31164214,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sumatriptan,DB00669
,50865,DB06655,10013968,81,3607,35,2084,0.172663348,1.33705012,0.885390313,2.056417874,0.314341865,DB0665510013968_,1.157274142,0.290465785,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,liraglutide,DB06655
,50866,DB00230,10022116,57,19617,16,8635,0.126605163,1.568118044,0.887495628,2.927332933,0.250928721,DB0023010022116_,1.382586359,0.449876202,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,50869,DB00656,10022116,46,11967,8,6611,0.000941145,3.176343546,1.483350357,7.798719064,0.005239436,DB0065610022116_,5.25154136,1.155730707,female,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,50876,DB00660,10033371,65,1192,8,359,0.01426872,2.446150683,1.156004817,5.959368909,0.047304446,DB0066010033371_,3.051150995,0.894515639,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,metaxalone,DB00660
,50877,DB00887,10033371,109,2232,43,1772,8.22495858175956e-05,2.01211219,1.393091304,2.951263119,0.000675076,DB0088710033371_,7.300685525,0.699185011,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,50879,DB06655,10033371,60,3628,20,2099,0.034865392,1.735514992,1.027875551,3.0490084,0.095159838,DB0665510033371_,2.352197292,0.551304195,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,liraglutide,DB06655
,50880,DB00186,10037377,139,16762,80,9928,0.888418834,1.029107852,0.775174155,1.374091627,0.953788839,DB0018610037377_,0.047312975,0.028692264,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,50881,DB00230,10037377,68,19606,45,8606,0.040082576,0.663308462,0.448146646,0.990209973,0.105849491,DB0023010037377_,2.245737093,-0.410515144,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,50884,DB00656,10037377,67,11946,34,6585,0.754948935,1.086252115,0.707823706,1.694941793,0.862429787,DB0065610037377_,0.14800154,0.082733345,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,50912,DB00564,10033295,52,2552,32,1431,0.73058608,0.911220061,0.572618967,1.470141072,0.843292426,DB0056410033295_,0.170441494,-0.092970851,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,carbamazepine,DB00564
,50923,DB00112,10041101,84,5849,14,4077,1.83570040968455e-08,4.181761928,2.355023726,7.988183411,3.87405742822629e-07,DB0011210041101_,14.76379326,1.430732672,female,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,50926,DB00526,10053762,103,1495,119,1775,0.889319123,1.027656141,0.774384787,1.361976365,0.953995558,DB0052610053762_,0.047096264,0.027280618,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,oxaliplatin,DB00526
,50927,DB00016,10003549,141,2621,116,2174,1,1.008214859,0.777604093,1.309244586,1,DB0001610003549_,0,0.008181301,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,50928,DB00531,10003549,173,7079,128,6388,0.102076052,1.219614027,0.962321392,1.549000214,0.21408035,DB0053110003549_,1.541403869,0.198534438,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,50929,DB00541,10003549,52,3082,84,4213,0.381221592,0.846246326,0.585056848,1.214168146,0.551238285,DB0054110003549_,0.595588104,-0.166944796,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,vincristine,DB00541
,50946,DB00016,10053762,182,2580,138,2152,0.417429352,1.100005926,0.870123152,1.393149058,0.586524192,DB0001610053762_,0.533541364,0.095315567,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,erythropoietin,DB00016
,50947,DB00889,10053762,131,649,108,409,0.067533027,0.764584142,0.570462024,1.026013388,0.156912888,DB0088910053762_,1.852064484,-0.268423198,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,granisetron,DB00889
,50961,DB00343,10002034,204,8532,107,4988,0.405240159,1.114617093,0.875397551,1.425735979,0.574919327,DB0034310002034_,0.553525549,0.108510932,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,diltiazem,DB00343
,50966,DB00343,10005750,80,8656,26,5069,0.008361472,1.801791066,1.143135053,2.926921088,0.030842168,DB0034310005750_,3.47887243,0.588781207,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,diltiazem,DB00343
,50967,DB00433,10005750,52,7604,44,5976,0.757323112,0.92880075,0.608734722,1.422815243,0.864342415,DB0043310005750_,0.145786275,-0.073861041,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,prochlorperazine,DB00433
,50969,DB00741,10005750,33,4061,32,3142,0.381107566,0.797909061,0.4744166,1.343487444,0.551118882,DB0074110005750_,0.595804736,-0.225760647,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,hydrocortisone,DB00741
,50970,DB00904,10005750,189,22880,106,14350,0.368328965,1.118302192,0.87611165,1.433638632,0.538039422,DB0090410005750_,0.619823446,0.111811635,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,ondansetron,DB00904
,50971,DB00959,10005750,92,7986,34,4968,0.009652576,1.683234645,1.122474879,2.577768957,0.034597119,DB0095910005750_,3.363984866,0.520717326,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,methylprednisolone,DB00959
,50972,DB01067,10005750,22,4339,43,4780,0.033390677,0.563664059,0.320532735,0.965116164,0.092129738,DB0106710005750_,2.384557502,-0.573296845,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,glipizide,DB01067
,50976,DB00433,10008531,100,7556,63,5957,0.177473825,1.251375824,0.902207046,1.74692642,0.320628303,DB0043310008531_,1.13747276,0.224243605,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,50978,DB00741,10008531,49,4045,49,3125,0.219036821,0.772592552,0.507712444,1.175645814,0.372362811,DB0074110008531_,0.987886602,-0.258003469,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,50979,DB00904,10008531,255,22814,168,14288,0.615647475,0.950621133,0.778426039,1.163352448,0.757016036,DB0090410008531_,0.278370842,-0.050639683,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,50980,DB00959,10008531,96,7982,73,4929,0.202304901,0.812095905,0.591447184,1.119017493,0.351692936,DB0095910008531_,1.044996824,-0.208136836,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,50982,DB01229,10008531,63,5678,43,2666,0.074352868,0.687937462,0.458166328,1.04161713,0.168785313,DB0122910008531_,1.779127709,-0.374057344,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,50993,DB00741,10016256,283,3811,235,2939,0.434673337,0.92871794,0.773069383,1.116404456,0.603177524,DB0074110016256_,0.505543724,-0.073950203,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,51008,DB00343,10061818,66,8670,59,5036,0.01953542,0.649817603,0.449579628,0.941074141,0.060692455,DB0034310061818_,2.801935882,-0.431063567,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,51010,DB00741,10061818,35,4059,53,3121,0.002278055,0.50782611,0.320712499,0.795171655,0.010820146,DB0074110061818_,4.526345529,-0.677616194,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,51011,DB01067,10061818,33,4328,56,4767,0.054586625,0.649090708,0.408048085,1.017757463,0.13360114,DB0106710061818_,2.012896487,-0.432182806,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,51012,DB01075,10061818,205,19743,134,10963,0.154225541,0.84951586,0.679090596,1.06559806,0.289837941,DB0107510061818_,1.238433338,-0.163088668,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,51014,DB00441,10027457,44,2230,13,1881,0.000440959,2.854160566,1.50431323,5.793838095,0.002780855,DB0044110027457_,5.884996833,1.048777777,female,10027457,Metastases to liver,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,gemcitabine,DB00441
,51022,DB01229,10000060,59,5682,13,2696,0.01069985,2.153246545,1.165081437,4.287476402,0.037568482,DB0122910000060_,3.281589827,0.766976724,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,paclitaxel,DB01229
,51026,DB01229,10003445,65,5676,16,2693,0.016515337,1.927337827,1.099908338,3.576412845,0.053133748,DB0122910003445_,2.934943002,0.656139686,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,paclitaxel,DB01229
,51033,DB00108,10058080,49,10145,21,3274,0.267230245,0.753031723,0.442444315,1.324038601,0.429506358,DB0010810058080_,0.845118733,-0.283647923,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,natalizumab,DB00108
,51049,DB01016,10002034,21,1080,36,1192,0.138980843,0.643948526,0.354817066,1.141315852,0.268403914,DB0101610002034_,1.315262292,-0.440136485,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,glyburide,DB01016
,51054,DB00758,10020993,43,8257,51,10023,0.917627411,1.023471913,0.665134395,1.568300174,0.963386915,DB0075810020993_,0.037300167,0.023200683,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,clopidogrel,DB00758
,51055,DB01016,10020993,26,1075,77,1151,4.00748928876903e-06,0.361655659,0.220722229,0.575770575,4.86769204969011e-05,DB0101610020993_,9.930305552,-1.017062737,male,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,glyburide,DB01016
,51056,DB01076,10020993,87,25660,100,25483,0.341125236,0.864002033,0.640306569,1.163962846,0.510285224,DB0107610020993_,0.672785447,-0.146180158,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,51071,DB00104,10053762,60,1421,49,1028,0.552964644,0.885881783,0.59180753,1.331484356,0.706647333,DB0010410053762_,0.34722356,-0.121171765,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,octreotide,DB00104
,51072,DB00650,10053762,134,1997,125,1889,0.948837362,1.014023078,0.782096085,1.315489555,0.987202488,DB0065010053762_,0.012880106,0.013925664,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,leucovorin,DB00650
,51073,DB00104,10061818,30,1451,26,1051,0.584480406,0.835826366,0.474643743,1.480822489,0.732270592,DB0010410061818_,0.311605172,-0.179334383,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,octreotide,DB00104
,51082,DB00316,10018276,47,65427,22,36931,0.531513757,1.205857332,0.712310483,2.101692236,0.688337354,DB0031610018276_,0.37347622,0.187190793,NA,10018276,Gingival bleeding,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,51089,DB00028,10028810,276,13182,110,5505,0.735018068,1.047824294,0.835102809,1.3222556,0.846827671,DB0002810028810_,0.166258063,0.046715914,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,51090,DB00073,10028810,46,7360,28,6379,0.160744655,1.423844843,0.870119308,2.368569816,0.298535523,DB0007310028810_,1.208866347,0.353360849,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,rituximab,DB00073
,51091,DB01075,10028810,341,19607,145,10952,0.006486929,1.313605658,1.076910076,1.608848871,0.025198986,DB0107510028810_,3.680951543,0.272775767,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,51092,DB00335,10033557,98,8368,25,5440,1.00883308701439e-05,2.548213287,1.626343952,4.13356346,0.000109462,DB0033510033557_,9.119932792,0.935392442,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,atenolol,DB00335
,51103,DB00773,10002034,80,2243,116,2711,0.241643515,0.833580889,0.615440461,1.124425966,0.399723083,DB0077310002034_,0.916983265,-0.182024534,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,etoposide,DB00773
,51112,DB00773,10003549,46,2277,71,2756,0.222195906,0.784217209,0.526760615,1.157648017,0.37630356,DB0077310003549_,0.977359122,-0.243069245,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,etoposide,DB00773
,51113,DB00541,10013573,42,3092,57,4240,1,1.01041769,0.659793591,1.536395412,1,DB0054110013573_,0,0.0103638,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,vincristine,DB00541
,51114,DB00773,10013573,30,2293,31,2796,0.520986052,1.179987893,0.687765048,2.02193432,0.679980057,DB0077310013573_,0.385691809,0.165504178,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,etoposide,DB00773
,51117,DB00682,10013971,516,18943,165,16199,2.391867073325e-31,2.674082889,2.237016261,3.210329788,5.84839311835792e-29,DB0068210013971_,65.00880075,0.983606476,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,51130,DB00635,10061520,96,32957,37,23757,0.001054733,1.870280761,1.267098937,2.812909226,0.005759564,DB0063510061520_,5.156893534,0.626088559,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,51133,DB01088,10008479,75,1354,19,418,0.532286928,1.218480908,0.718680415,2.161494143,0.689117958,DB0108810008479_,0.372342821,0.197604925,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,iloprost,DB01088
,51134,DB01088,10012735,78,1351,18,419,0.322112509,1.34372176,0.786210601,2.413092924,0.490475997,DB0108810012735_,0.712378937,0.295443197,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,iloprost,DB01088
,51135,DB00203,10016825,529,13349,196,8742,3.56266807070071e-12,1.767463308,1.49399111,2.097632981,1.4631989099745e-10,DB0020310016825_,22.64522586,0.569545359,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,sildenafil,DB00203
,51136,DB00682,10016825,407,19052,121,16243,1.20267742498559e-27,2.867500747,2.332825345,3.546335432,2.27427166300332e-25,DB0068210016825_,56.74296747,1.053440831,female,10016825,Flushing,10047065,Vascular disorders,Vasc,warfarin,DB00682
,51137,DB01088,10016825,36,1393,24,413,0.004640376,0.444948857,0.254901403,0.78923503,0.019253717,DB0108810016825_,3.950051157,-0.809795931,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,iloprost,DB01088
,51138,DB01088,10019211,165,1264,39,398,0.136529574,1.331921183,0.916009443,1.975676868,0.264847222,DB0108810019211_,1.328602142,0.286622399,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,iloprost,DB01088
,51140,DB01088,10033371,53,1376,7,430,0.02935278,2.365364457,1.060968334,6.212897582,0.083274454,DB0108810033371_,2.485613456,0.860932114,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,iloprost,DB01088
,51141,DB01088,10033433,38,1391,16,421,0.326760417,0.718955132,0.386826928,1.395751935,0.495180027,DB0108810033433_,0.702833891,-0.329956326,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,iloprost,DB01088
,51155,DB00203,10053377,88,13790,28,8910,0.000781496,2.030600623,1.312710188,3.230505718,0.004487029,DB0020310053377_,5.40656438,0.708331623,NA,10053377,Central venous catheterisation,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,51156,DB00374,10053377,72,17644,24,5700,0.905314733,0.969167521,0.602519947,1.610575427,0.957805461,DB0037410053377_,0.04311059,-0.031317801,NA,10053377,Central venous catheterisation,10042613,Surgical and medical procedures,Surg,treprostinil,DB00374
,51157,DB00682,10053377,92,19367,19,16345,3.18249055893774e-10,4.086325383,2.473057064,7.098080571,9.63730003936388e-09,DB0068210053377_,18.45762485,1.407646127,female,10053377,Central venous catheterisation,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,51160,DB06403,10056520,68,21403,14,6647,0.192742768,1.508403942,0.839663858,2.906142415,0.340084826,DB0640310056520_,1.078560203,0.4110521,NA,10056520,Catheter site infection,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,51161,DB00682,10064687,298,19161,80,16284,2.12383427610503e-23,3.165459104,2.463139643,4.107666216,2.94590944313565e-21,DB0068210064687_,47.27386937,1.152298102,female,10064687,Device related infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,51173,DB00531,10005483,21,7231,44,6472,0.001087552,0.427199574,0.240981601,0.734882562,0.005904536,DB0053110005483_,5.132034415,-0.850503989,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,cyclophosphamide,DB00531
,51175,DB00635,10005483,124,32929,189,23605,5.14347962109221e-11,0.47031219,0.371683222,0.593381083,1.75693777570382e-09,DB0063510005483_,20.15969344,-0.754358571,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,prednisone,DB00635
,51177,DB01234,10005483,121,31504,158,32730,0.06275036,0.795629617,0.622296001,1.01514274,0.14858729,DB0123410005483_,1.906582682,-0.228621507,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,dexamethasone,DB01234
,51179,DB00997,10015090,41,5290,18,3496,0.181522901,1.50524682,0.844012214,2.788417322,0.325788089,DB0099710015090_,1.121508143,0.408956885,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxorubicin,DB00997
,51180,DB00531,10018884,127,7125,173,6343,0.000347362,0.653559318,0.514291484,0.82874422,0.002280319,DB0053110018884_,6.083439957,-0.42532198,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,cyclophosphamide,DB00531
,51181,DB00541,10018884,35,3099,52,4245,0.744279424,0.921971698,0.581373961,1.446537257,0.853959003,DB0054110018884_,0.157872093,-0.081240753,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,vincristine,DB00541
,51182,DB01234,10018884,394,31231,361,32527,0.085206905,1.136700252,0.982056525,1.315980422,0.187082947,DB0123410018884_,1.676203194,0.128129549,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,51189,DB00541,10025482,40,3094,46,4251,0.442678999,1.19470445,0.760015967,1.871070966,0.610691868,DB0054110025482_,0.493162755,0.177898833,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,vincristine,DB00541
,51190,DB00997,10025482,70,5261,37,3477,0.320270741,1.250312023,0.825853596,1.920579844,0.488485591,DB0099710025482_,0.716445304,0.223393139,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,51191,DB01234,10025482,672,30953,469,32419,1.57745102192767e-11,1.500678358,1.33035229,1.693892208,5.81532960888763e-10,DB0123410025482_,21.26535346,0.405917245,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,51196,DB01234,10038063,62,31563,57,32831,0.521530382,1.13141402,0.776518243,1.651139602,0.680335795,DB0123410038063_,0.385168787,0.123468196,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,51234,DB00073,10028411,64,7342,45,6362,0.290762495,1.232366275,0.827343096,1.849488721,0.456062309,DB0007310028411_,0.785125836,0.208936122,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,rituximab,DB00073
,51237,DB00331,10003662,17,24929,35,20717,0.001909544,0.403654316,0.211970789,0.740353667,0.009368615,DB0033110003662_,4.670390053,-0.907196421,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,metformin,DB00331
,51239,DB00331,10034474,38,24908,48,20704,0.064761121,0.658062044,0.418179702,1.02898161,0.152033767,DB0033110034474_,1.883652632,-0.41845606,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,metformin,DB00331
,51242,DB00112,10000081,260,5673,123,3968,0.000375661,1.478462565,1.183716178,1.854697131,0.002434176,DB0011210000081_,6.018146845,0.391002741,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,51247,DB00635,10009802,38,33015,46,23748,0.019706776,0.594231394,0.376120553,0.933829092,0.06109078,DB0063510009802_,2.795394332,-0.520486484,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,51253,DB00112,10020751,39,5894,19,4072,0.229891494,1.418057234,0.798615607,2.602059808,0.385856001,DB0011210020751_,0.952291033,0.34928779,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,bevacizumab,DB00112
,51257,DB00112,10037377,70,5863,68,4023,0.044883737,0.706387793,0.497376653,1.003707759,0.11536391,DB0011210037377_,2.159663708,-0.347590911,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bevacizumab,DB00112
,51262,DB00112,10051055,48,5885,58,4033,0.003879629,0.567194919,0.377841383,0.847975798,0.016636928,DB0011210051055_,4.096130452,-0.567052262,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,bevacizumab,DB00112
,51280,DB00563,10009802,24,46622,53,15295,4.85586928679606e-16,0.148562644,0.087667812,0.245013891,3.37662762442948e-14,DB0056310009802_,31.01931383,-1.906748567,male,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,methotrexate,DB00563
,51283,DB00987,10012174,17,2087,65,2863,6.36568655074501e-05,0.358856881,0.196616101,0.62168109,0.000541495,DB0098710012174_,7.521176032,-1.024831629,male,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,cytarabine,DB00987
,51285,DB01181,10016288,84,489,180,740,0.017610269,0.706364837,0.525269458,0.94453342,0.055944444,DB0118110016288_,2.883396148,-0.347623408,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,ifosfamide,DB01181
,51287,DB00563,10020578,24,46622,38,15310,1.17376352990111e-09,0.207429316,0.11898513,0.354935068,3.21211602118174e-08,DB0056310020578_,17.25375083,-1.572964641,male,10020578,Hyperbilirubinaemia,10019805,Hepatobiliary disorders,Hepat,methotrexate,DB00563
,51288,DB00987,10020578,20,2084,37,2891,0.345426072,0.749899607,0.411130481,1.330341377,0.514858196,DB0098710020578_,0.663863763,-0.287815939,NA,10020578,Hyperbilirubinaemia,10019805,Hepatobiliary disorders,Hepat,cytarabine,DB00987
,51290,DB00563,10021097,237,46409,146,15202,6.38484147410007e-09,0.531763387,0.430473116,0.65863097,1.49978157414406e-07,DB0056310021097_,15.71277617,-0.631556649,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,methotrexate,DB00563
,51292,DB00073,10028116,36,7370,79,6328,1.84316308148564e-06,0.391292508,0.255843104,0.588268563,2.46552374538677e-05,DB0007310028116_,10.61052121,-0.938299897,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,51293,DB00563,10028116,136,46510,205,15143,9.60585674608192e-44,0.216026693,0.17245827,0.269838628,4.31606742856005e-41,DB0056310028116_,92.94364414,-1.532353299,male,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,51294,DB00987,10028116,44,2060,85,2843,0.085425752,0.714450171,0.482593621,1.045037499,0.187414732,DB0098710028116_,1.674431302,-0.336242023,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,cytarabine,DB00987
,51296,DB00987,10038435,32,2072,51,2877,0.576320539,0.871270605,0.539768061,1.387517262,0.725593839,DB0098710038435_,0.320764872,-0.137802668,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,cytarabine,DB00987
,51298,DB00563,10038695,189,46457,140,15208,1.42505096498706e-12,0.441933142,0.353020191,0.554343894,6.2481175337256e-11,DB0056310038695_,23.4961558,-0.81659667,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,51300,DB01181,10040047,19,554,60,860,0.008509072,0.491790882,0.274032991,0.846417181,0.031290005,DB0118110040047_,3.464456555,-0.70970169,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ifosfamide,DB01181
,51301,DB00073,10048294,47,7359,36,6371,0.65908686,1.130253661,0.715726764,1.798437648,0.791749239,DB0007310048294_,0.233510554,0.122442087,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,rituximab,DB00073
,51302,DB00563,10048294,89,46557,79,15269,4.39081068331094e-10,0.369485034,0.269668809,0.507023139,1.29895845594629e-08,DB0056310048294_,18.15911799,-0.995645043,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,51303,DB00987,10048294,41,2063,44,2884,0.267316934,1.30256462,0.826712097,2.048431898,0.429606287,DB0098710048294_,0.844886102,0.264335105,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,cytarabine,DB00987
,51312,DB01075,10017944,68,19880,26,11071,0.106745998,1.456468215,0.913946394,2.386499933,0.221244169,DB0107510017944_,1.508488352,0.376014474,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,51319,DB00091,10053762,275,5235,162,2508,0.046233548,0.813297446,0.663292753,0.999675284,0.117950967,DB0009110053762_,2.137486278,-0.206658374,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclosporine,DB00091
,51334,DB00783,10037660,189,16525,7,366,0.208173306,0.598029164,0.281808337,1.518485719,0.358997202,DB0078310037660_,1.024440684,-0.514115757,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,estradiol,DB00783
,51342,DB00072,10000081,88,3635,8,327,1,0.989547852,0.475132878,2.384555308,1,DB0007210000081_,0,-0.010507155,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,trastuzumab,DB00072
,51344,DB00028,10003549,228,13230,98,5517,0.806463048,0.970179632,0.760666399,1.244962902,0.89538876,DB0002810003549_,0.110497286,-0.030274037,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,51345,DB01029,10003549,53,1287,35,866,1,1.018929136,0.646383279,1.62380735,1,DB0102910003549_,0,0.01875221,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,irbesartan,DB01029
,51354,DB00455,10036790,47,9354,27,5091,0.808477693,0.947418092,0.577287997,1.584023428,0.896621922,DB0045510036790_,0.109120998,-0.054014792,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,51356,DB00028,10048959,162,13296,62,5553,0.605971833,1.091258026,0.808094291,1.489586855,0.748987568,DB0002810048959_,0.289032893,0.087331183,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,51357,DB00073,10048959,77,7329,45,6362,0.036041392,1.485298702,1.013507064,2.199401751,0.097614425,DB0007310048959_,2.326729996,0.395615898,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,51358,DB00343,10048959,246,8490,81,5014,3.09485905759187e-06,1.793533095,1.386277468,2.340792574,3.893197909969e-05,DB0034310048959_,10.15369456,0.584187471,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,51359,DB01029,10048959,38,1302,13,888,0.030578447,1.993050029,1.03137379,4.102408006,0.085990637,DB0102910048959_,2.453516856,0.689666143,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,irbesartan,DB01029
,51360,DB00028,10053762,130,13328,117,5498,2.34391417274614e-09,0.458362486,0.353560246,0.594761676,6.04017490496395e-08,DB0002810053762_,16.62224777,-0.780094955,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,human immunoglobulin g,DB00028
,51361,DB01029,10053762,42,1298,21,880,0.297863812,1.355753177,0.77876629,2.427575087,0.463752088,DB0102910053762_,0.768405162,0.30435715,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,irbesartan,DB01029
,51362,DB00193,10019063,116,19204,77,8625,0.009803072,0.676609579,0.502307512,0.915740999,0.035018298,DB0019310019063_,3.351884562,-0.390660865,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,51364,DB00316,10033864,43,65431,28,36925,0.5396777,0.8666638,0.526107632,1.448913135,0.695449361,DB0031610033864_,0.363197079,-0.143104151,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,51387,DB00997,10061822,32,5299,25,3489,0.587387528,0.842806837,0.48299511,1.486197166,0.73446144,DB0099710061822_,0.308617783,-0.171017484,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,51396,DB00762,10053762,176,987,220,1149,0.546033969,0.931303499,0.745746234,1.161896336,0.700725054,DB0076210053762_,0.355639689,-0.071170062,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,irinotecan,DB00762
,51397,DB00112,10003988,146,5787,97,3994,0.791927688,1.038809248,0.795423059,1.361610483,0.887327647,DB0011210003988_,0.119540977,0.038075103,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bevacizumab,DB00112
,51398,DB00530,10003988,30,1778,24,1244,0.676381069,0.874618982,0.491647223,1.571423358,0.80384645,DB0053010003988_,0.21834701,-0.133966936,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,erlotinib,DB00530
,51402,DB00958,10035598,67,4527,40,2545,0.761694617,0.941664155,0.625173643,1.434551895,0.867966655,DB0095810035598_,0.141601982,-0.060106591,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carboplatin,DB00958
,51403,DB01229,10035598,105,5636,40,2669,0.281402867,1.243039378,0.853241643,1.842488875,0.445341342,DB0122910035598_,0.80891423,0.217559492,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,paclitaxel,DB01229
,51404,DB00530,10061428,83,1725,59,1209,0.930700144,0.985970182,0.691693605,1.412789862,0.971871096,DB0053010061428_,0.028532101,-0.014129166,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,erlotinib,DB00530
,51405,DB01229,10061428,173,5568,69,2640,0.263412355,1.188738609,0.890586351,1.601535612,0.425228049,DB0122910061428_,0.855129668,0.172892753,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,paclitaxel,DB01229
,51406,DB00005,10062355,1432,126650,634,41785,1.96187453990187e-09,0.745194885,0.677719521,0.820064417,5.13880142315104e-08,DB0000510062355_,16.78386088,-0.294109504,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,51407,DB00530,10016256,171,1637,115,1153,0.752608753,1.047311242,0.81178575,1.354852501,0.860624775,DB0053010016256_,0.150096671,0.046226158,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,erlotinib,DB00530
,51420,DB01229,10000059,49,5692,13,2696,0.074788304,1.785176806,0.951706772,3.59365874,0.169499856,DB0122910000059_,1.774903204,0.579517461,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,paclitaxel,DB01229
,51429,DB00958,10008469,36,4558,14,2571,0.300587228,1.450377167,0.761691134,2.916757026,0.466820401,DB0095810008469_,0.761810676,0.371823638,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,51430,DB01229,10008469,94,5647,16,2693,3.20235413575247e-05,2.801456182,1.634379706,5.112325923,0.000300514,DB0122910008469_,8.11001732,1.030139347,female,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,51431,DB01248,10008469,39,2661,12,1362,0.13704024,1.663283098,0.849788636,3.501315097,0.265573244,DB0124810008469_,1.325864604,0.508793419,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,51432,DB00099,10012735,137,2248,74,1881,0.002848729,1.548950127,1.150899208,2.098199188,0.012963787,DB0009910012735_,4.345595433,0.437577364,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,filgrastim,DB00099
,51434,DB00099,10013968,77,2308,48,1907,0.144461274,1.325366553,0.907420843,1.952597281,0.276291215,DB0009910013968_,1.286299842,0.281689065,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,filgrastim,DB00099
,51435,DB00762,10013968,44,1119,24,1345,0.00189922,2.202941175,1.301313937,3.812996711,0.00932493,DB0076210013968_,4.675063874,0.789793365,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,irinotecan,DB00762
,51436,DB00958,10013968,281,4313,145,2440,0.405202776,1.096349368,0.88833116,1.357509149,0.574908505,DB0095810013968_,0.553544372,0.091985904,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carboplatin,DB00958
,51438,DB00762,10016256,127,1036,129,1240,0.233803049,1.178274541,0.901949088,1.539156807,0.390563275,DB0076210016256_,0.940165286,0.164051115,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,irinotecan,DB00762
,51462,DB01229,10028391,37,5704,13,2696,0.447512201,1.345234024,0.697467174,2.76246438,0.615276608,DB0122910028391_,0.485683343,0.296567993,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,paclitaxel,DB01229
,51464,DB00099,10029331,38,2347,35,1920,0.636518614,0.888210909,0.543899025,1.454247819,0.774058699,DB0009910029331_,0.256107569,-0.118546054,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,filgrastim,DB00099
,51470,DB00958,10030124,51,4543,11,2574,0.002073066,2.626592797,1.34882048,5.599788334,0.010019406,DB0095810030124_,4.603231499,0.965687492,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,51471,DB01229,10030124,71,5670,28,2681,0.45000652,1.198942438,0.762147405,1.933843562,0.617672134,DB0122910030124_,0.481797489,0.181439867,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,51472,DB01248,10030124,39,2661,27,1347,0.237448367,0.731208358,0.43426786,1.247932125,0.394820998,DB0124810030124_,0.929322787,-0.313056828,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,51477,DB00958,10033425,72,4522,27,2558,0.073230094,1.508395774,0.954171407,2.449243403,0.166892358,DB0095810033425_,1.790406239,0.411046685,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,carboplatin,DB00958
,51482,DB01248,10035598,51,2649,31,1343,0.47901998,0.834120387,0.520776272,1.355495701,0.644191255,DB0124810035598_,0.439759617,-0.181377538,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docetaxel,DB01248
,51484,DB00441,10037844,62,2212,35,1859,0.063742817,1.48859463,0.9633541,2.332943166,0.150206638,DB0044110037844_,1.895743344,0.397832474,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,gemcitabine,DB00441
,51485,DB00762,10037844,35,1128,34,1335,0.463041215,1.218220145,0.732613694,2.027789754,0.630182947,DB0076210037844_,0.46174511,0.197390896,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,irinotecan,DB00762
,51554,DB00099,10061818,52,2333,36,1919,0.450523816,1.188074733,0.758436366,1.879273107,0.618232874,DB0009910061818_,0.480890074,0.172334126,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,filgrastim,DB00099
,51565,DB01109,10011224,103,4309,57,4213,0.000566712,1.766635681,1.262344035,2.493681184,0.003424765,DB0110910011224_,5.676722382,0.569076993,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,heparin,DB01109
,51566,DB01109,10013968,214,4198,165,4105,0.027244746,1.268199668,1.02542405,1.570659665,0.078544354,DB0110910013968_,2.54409179,0.237598311,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,heparin,DB01109
,51576,DB01109,10033425,68,4344,37,4233,0.004274591,1.790749457,1.179989507,2.75610522,0.018026251,DB0110910033425_,4.015926169,0.582634223,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,heparin,DB01109
,51577,DB01075,10030124,176,19772,106,10991,0.532681263,0.922986096,0.720377029,1.187258387,0.689482802,DB0107510030124_,0.371813524,-0.080141109,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,51589,DB00377,10025482,43,1076,29,694,0.902188328,0.956400127,0.577321489,1.604730713,0.957195726,DB0037710025482_,0.043747388,-0.044578911,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,palonosetron,DB00377
,51590,DB00441,10000081,144,2130,71,1823,0.000181437,1.735618223,1.287845111,2.356669513,0.001328806,DB0044110000081_,6.623474696,0.551363674,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,gemcitabine,DB00441
,51591,DB01101,10000081,164,7425,74,3834,0.36889598,1.144348962,0.861954561,1.531322411,0.538525033,DB0110110000081_,0.618921296,0.134835884,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,51592,DB01229,10000081,214,5527,82,2627,0.112847348,1.240358515,0.952950336,1.627247316,0.230348104,DB0122910000081_,1.46816362,0.215400463,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,paclitaxel,DB01229
,51593,DB00441,10012174,81,2193,54,1840,0.218751024,1.258479901,0.875727948,1.820803697,0.372003407,DB0044110012174_,0.988852266,0.229904565,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,gemcitabine,DB00441
,51594,DB01101,10012174,207,7382,110,3798,0.80999324,0.968158922,0.761942835,1.235728208,0.897715289,DB0110110012174_,0.107902311,-0.03235903,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,capecitabine,DB01101
,51602,DB00399,10013781,56,6936,13,4985,7.03390351623616e-05,3.095705047,1.669833148,6.178538093,0.000588997,DB0039910013781_,7.437089491,1.130015682,female,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,51604,DB00497,10013781,97,19170,58,16317,0.035575767,1.423497712,1.017052141,2.007693022,0.096642107,DB0049710013781_,2.336740743,0.35311702,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,51609,DB00497,10017885,88,19179,51,16324,0.032695083,1.468613448,1.027945713,2.117534218,0.090605192,DB0049710017885_,2.401243756,0.384318723,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,51611,DB01101,10017885,40,7549,11,3897,0.07440482,1.877098363,0.943919651,4.060753562,0.168852207,DB0110110017885_,1.778731462,0.62972716,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,51615,DB00497,10020765,50,19217,31,16344,0.181114981,1.371754778,0.858856977,2.222683449,0.325222522,DB0049710020765_,1.123245648,0.31609078,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,51624,DB01101,10035598,58,7531,11,3897,0.001253995,2.72823281,1.415749277,5.771597896,0.006626712,DB0110110035598_,5.016646497,1.003654077,female,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,capecitabine,DB01101
,51625,DB01101,10043554,69,7520,34,3874,0.916866148,1.045469047,0.682389917,1.62931822,0.962980568,DB0110110043554_,0.037722046,0.044465633,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,capecitabine,DB01101
,51626,DB01229,10043554,154,5587,72,2637,1,1.009530011,0.75518374,1.360168203,1,DB0122910043554_,0,0.009484887,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,paclitaxel,DB01229
,51627,DB00441,10047895,68,2206,42,1852,0.145198477,1.359135951,0.906885127,2.057739147,0.27732466,DB0044110047895_,1.282566403,0.306849167,NA,10047895,Weight decreased,10022891,Investigations,Inv,gemcitabine,DB00441
,51628,DB00112,10050584,30,5903,21,4070,1,0.984968841,0.54460095,1.812792708,1,DB0011210050584_,0,-0.015145272,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,bevacizumab,DB00112
,51629,DB00497,10050584,119,19148,65,16310,0.003768539,1.559400551,1.142226902,2.145267324,0.016254686,DB0049710050584_,4.119374052,0.444301485,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,51632,DB14726,10009802,41,1976,52,2796,0.597316692,1.115630097,0.719224759,1.720430638,0.742483875,DB1472610009802_,0.297754126,0.109419355,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,dabigatran,DB14726
,51635,DB00476,10005557,93,17164,46,6131,0.081670784,0.722178387,0.501328912,1.053168242,0.181149871,DB0047610005557_,1.708430572,-0.325483098,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,duloxetine,DB00476
,51639,DB01285,10005557,42,1234,27,582,0.23801604,0.733760094,0.437087699,1.250760062,0.395527208,DB0128510005557_,0.9275357,-0.309573151,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,corticotropin,DB01285
,51641,DB08868,10005557,73,9129,21,2490,0.801477373,0.948154381,0.575595151,1.625753381,0.892586762,DB0886810005557_,0.113631557,-0.053237941,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,fingolimod,DB08868
,51666,DB00231,10013573,109,3187,57,2082,0.19683584,1.249195835,0.894048159,1.761321792,0.345186647,DB0023110013573_,1.063670003,0.222500012,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,temazepam,DB00231
,51667,DB00745,10013573,115,2462,32,1051,0.033960656,1.53396703,1.021284942,2.362458754,0.093315475,DB0074510013573_,2.371769317,0.42785721,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,modafinil,DB00745
,51668,DB00843,10013573,68,2126,81,2092,0.27860499,0.826117962,0.586020852,1.161646679,0.442401762,DB0084310013573_,0.815536845,-0.191017705,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,donepezil,DB00843
,51669,DB01285,10013573,37,1239,15,594,0.653931971,1.182447156,0.627621402,2.33841802,0.787852518,DB0128510013573_,0.238444366,0.167586152,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,corticotropin,DB01285
,51671,DB08868,10013573,464,8738,114,2397,0.323430577,1.116515529,0.903026666,1.38969766,0.491877959,DB0886810013573_,0.709524643,0.110212701,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,51672,DB00231,10013709,165,3131,75,2064,0.008376317,1.45017518,1.090618111,1.94291151,0.030886091,DB0023110013709_,3.477449319,0.371684363,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,51673,DB00745,10013709,162,2415,70,1013,0.824029539,0.970761252,0.72158386,1.316857681,0.906757125,DB0074510013709_,0.097880643,-0.029674719,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,modafinil,DB00745
,51674,DB00843,10013709,114,2080,123,2050,0.504933591,0.913488916,0.696399751,1.197413041,0.665923054,DB0084310013709_,0.40658115,-0.090484037,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,donepezil,DB00843
,51677,DB00404,10013786,102,19790,32,9830,0.021536321,1.583258059,1.05423298,2.436683244,0.065545324,DB0040410013786_,2.725013402,0.459484787,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,51678,DB00476,10013786,64,17193,19,6158,0.533792295,1.206447935,0.712945744,2.134382202,0.690403763,DB0047610013786_,0.370478688,0.187680452,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,duloxetine,DB00476
,51683,DB01136,10013786,45,9839,37,11078,0.183231537,1.369342006,0.865872847,2.177763821,0.327947769,DB0113610013786_,1.114900923,0.314330337,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,carvedilol,DB01136
,51687,DB00169,10018358,40,38651,31,18144,0.041075684,0.605716611,0.369381152,1.00181577,0.107816493,DB0016910018358_,2.227324633,-0.501343042,NA,10018358,Glomerular filtration rate decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,51690,DB00316,10018358,36,65438,40,36913,0.003836547,0.507672015,0.314400614,0.817173546,0.01649254,DB0031610018358_,4.104847123,-0.67791968,NA,10018358,Glomerular filtration rate decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,51701,DB00230,10021097,172,19502,73,8578,0.834691163,1.036334923,0.782733894,1.383855518,0.914236904,DB0023010021097_,0.089665547,0.035690376,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,pregabalin,DB00230
,51702,DB00476,10021097,179,17078,85,6092,0.034854778,0.751212302,0.576118809,0.986023059,0.095145689,DB0047610021097_,2.352345992,-0.286066974,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,duloxetine,DB00476
,51703,DB00557,10021097,93,5894,69,2998,0.02338618,0.685583074,0.495106089,0.953249163,0.06976176,DB0055710021097_,2.662669275,-0.3774856,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,hydroxyzine,DB00557
,51705,DB00843,10021097,59,2135,48,2125,0.32831145,1.223350927,0.817449141,1.838824118,0.49690024,DB0084310021097_,0.699365998,0.201593755,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,donepezil,DB00843
,51708,DB08868,10021097,61,9141,7,2504,0.025193954,2.387032744,1.089264491,6.194034957,0.073927079,DB0886810021097_,2.604676093,0.870051065,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,fingolimod,DB08868
,51709,DB00169,10028596,163,38528,163,18012,1.44071859397845e-11,0.467501054,0.373636191,0.584927421,5.34876952580841e-10,DB0016910028596_,21.34898439,-0.760353676,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,51710,DB00230,10028596,129,19545,87,8564,0.002310297,0.649708574,0.490579641,0.863913518,0.010939681,DB0023010028596_,4.51535867,-0.431231364,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,pregabalin,DB00230
,51717,DB00476,10033425,466,16791,126,6051,0.004535479,1.332759997,1.089880126,1.639559456,0.018890042,DB0047610033425_,3.969120352,0.287251977,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,51718,DB00557,10033425,123,5864,43,3024,0.031128291,1.475050929,1.031318266,2.145195648,0.087197988,DB0055710033425_,2.439574024,0.388692517,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxyzine,DB00557
,51719,DB00745,10033425,55,2522,15,1068,0.146582785,1.552573058,0.860171986,2.97270716,0.279151927,DB0074510033425_,1.275999105,0.439913592,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,modafinil,DB00745
,51721,DB01285,10033425,48,1228,9,600,0.005946569,2.604775427,1.253362574,6.079064325,0.023498561,DB0128510033425_,3.750816106,0.957346463,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,corticotropin,DB01285
,51723,DB08868,10033425,316,8886,65,2446,0.03604365,1.338166428,1.017612857,1.782508983,0.097615511,DB0886810033425_,2.326718879,0.29130034,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,fingolimod,DB08868
,51739,DB00169,10040829,167,38524,53,18122,0.011236401,1.482219579,1.081612035,2.060038736,0.039080226,DB0016910040829_,3.242138671,0.39354068,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,51740,DB00230,10040829,60,19614,18,8633,0.175787894,1.467162243,0.853869795,2.642206514,0.31837558,DB0023010040829_,1.144523525,0.383330088,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,51742,DB00316,10040829,223,65251,88,36865,0.004453177,1.431685887,1.113414267,1.854604124,0.018618204,DB0031610040829_,3.983615489,0.358852692,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,51743,DB00404,10040829,72,19820,19,9843,0.013680079,1.881890899,1.121867386,3.306705609,0.045710403,DB0040410040829_,3.085429361,0.632277069,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,51748,DB01136,10040829,50,9834,29,11086,0.004508379,1.94356424,1.205186327,3.187964488,0.018802945,DB0113610040829_,3.973741771,0.664523525,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,carvedilol,DB01136
,51755,DB00316,10040952,45,65429,15,36938,0.080760191,1.69364367,0.926480581,3.271561011,0.179607549,DB0031610040952_,1.716981091,0.526882226,NA,10040952,Skin warm,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,51875,DB00073,10023232,63,7343,16,6391,2.05891696822504e-06,3.426601837,1.953312163,6.363038529,2.71884614467698e-05,DB0007310023232_,10.51271789,1.231569052,female,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,rituximab,DB00073
,51878,DB00734,10002855,79,3971,63,4839,0.01356374,1.527974071,1.080356188,2.168730105,0.045385131,DB0073410002855_,3.092570731,0.423942721,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,51879,DB00656,10003988,256,11757,97,6522,0.001345045,1.464010035,1.152114852,1.872909506,0.007026631,DB0065610003988_,4.958047855,0.38117927,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,51883,DB00734,10012735,75,3975,34,4868,8.34841748918468e-07,2.701158275,1.774257432,4.187814619,1.2223461962557e-05,DB0073410012735_,11.31215334,0.993680672,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,risperidone,DB00734
,51884,DB00656,10017885,80,11933,13,6606,5.60861275317588e-06,3.406532506,1.881423034,6.680147898,6.53757810275955e-05,DB0065610017885_,9.635358689,1.225694914,female,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,51888,DB00656,10022437,326,11687,193,6426,0.429264095,0.928752968,0.772850416,1.118517528,0.597801624,DB0065610022437_,0.514496313,-0.073912487,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,51889,DB00734,10022437,52,3998,60,4842,0.84863602,1.049646454,0.708048583,1.551424918,0.924540879,DB0073410022437_,0.078458012,0.048453397,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,51890,DB00734,10037377,31,4019,19,4883,0.021809495,1.982157665,1.083035881,3.719572408,0.066185138,DB0073410037377_,2.715299344,0.684185981,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,risperidone,DB00734
,51891,DB00656,10039073,79,11934,13,6606,5.50345202815551e-06,3.363669951,1.856465252,6.598090549,6.4321136754143e-05,DB0065610039073_,9.65162226,1.213032625,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,51895,DB00734,10039626,28,4022,44,4858,0.287429237,0.768659321,0.459924129,1.265140848,0.452334409,DB0073410039626_,0.79333353,-0.263107424,NA,10039626,Schizophrenia,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,51900,DB00656,10051055,42,11971,44,6575,0.00315247,0.524280613,0.334838634,0.819983135,0.0140875,DB0065610051055_,4.262467371,-0.645728217,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,trazodone,DB00656
,51902,DB00734,10053762,194,3856,322,4580,0.000315039,0.715634648,0.592615489,0.862417281,0.002101192,DB0073410053762_,6.165250707,-0.33458551,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,51903,DB00126,10002855,176,9995,61,5884,0.000306747,1.698475032,1.260140295,2.315788948,0.002054491,DB0012610002855_,6.187727208,0.529730809,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ascorbic acid,DB00126
,51905,DB00169,10003246,263,38428,68,18107,4.72269788582347e-06,1.82239034,1.390156039,2.417283507,5.6272037139107e-05,DB0016910003246_,9.785312822,0.600149013,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,51907,DB00126,10003553,89,10082,12,5933,2.01010455522563e-08,4.364218632,2.375754815,8.77066022,4.20330932650005e-07,DB0012610003553_,14.6822235,1.473439166,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,51909,DB01373,10003553,132,22588,17,7364,7.92613897874449e-05,2.531464977,1.521001354,4.479259719,0.000653816,DB0137310003553_,7.332684137,0.928798177,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,51910,DB13961,10003553,60,9397,16,6398,0.000400859,2.553058613,1.450174877,4.753326428,0.002567395,DB1396110003553_,5.964863414,0.937292096,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,51913,DB00169,10017076,42,38649,17,18158,0.676496782,1.160714489,0.646553864,2.175469694,0.80384645,DB0016910017076_,0.21834701,0.149035754,NA,10017076,Fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,51916,DB13961,10017885,96,9361,35,6379,0.001225486,1.869029792,1.255305649,2.840703794,0.006504825,DB1396110017885_,5.035211099,0.625419468,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,51919,DB00169,10021114,117,38574,26,18149,0.000295833,2.117217695,1.374388821,3.376242811,0.001994607,DB0016910021114_,6.217308464,0.750102819,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,cholecalciferol,DB00169
,51933,DB00126,10031161,57,10114,12,5933,0.000623073,2.786250153,1.476649282,5.711220887,0.003717929,DB0012610031161_,5.594588404,1.024696661,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,51934,DB00169,10031161,265,38426,35,18140,2.95410714775828e-16,3.573997539,2.504792922,5.243721458,2.09861368591423e-14,DB0016910031161_,31.49491432,1.273684728,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,51935,DB13961,10031161,75,9382,17,6397,9.02799980828111e-06,3.007896936,1.75734751,5.439049702,9.93514653383583e-05,DB1396110031161_,9.21684684,1.101241142,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,51936,DB00169,10031282,178,38513,18,18157,4.27733961097916e-14,4.662468789,2.864883027,8.049258184,2.28981408705881e-12,DB0016910031282_,26.80255049,1.539545091,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,51937,DB01373,10031282,165,22555,11,7370,2.89722260413163e-10,4.901268735,2.666720703,10.01645018,8.80387238723699e-09,DB0137310031282_,18.54807417,1.589494097,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,51938,DB13961,10033425,311,9146,114,6300,3.67708807757615e-09,1.87908688,1.507618297,2.355666843,9.07959230804031e-08,DB1396110033425_,16.21465145,0.630785957,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,51939,DB00169,10039073,349,38342,54,18121,7.37003739199376e-18,3.054443106,2.286713875,4.149732567,6.22898497905325e-16,DB0016910039073_,35.01214809,1.116597287,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,51941,DB01373,10039073,210,22510,20,7361,1.03060726432681e-09,3.43362286,2.165343374,5.741475471,2.85754345388505e-08,DB0137310039073_,17.37071842,1.233615931,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,51942,DB13961,10039073,84,9373,19,6395,2.45394242671172e-06,3.016179603,1.814775644,5.262524833,3.16651333756099e-05,DB1396110039073_,10.36029438,1.103990998,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,51943,DB00126,10041349,141,10030,47,5898,0.000591171,1.764049078,1.257613388,2.513501079,0.003551755,DB0012610041349_,5.640313297,0.567611779,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,51944,DB00169,10041349,421,38270,171,18004,0.110789673,1.158221744,0.966451316,1.393018206,0.227268628,DB0016910041349_,1.481622577,0.146885849,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,51946,DB13961,10041349,114,9343,61,6353,0.141326951,1.270752429,0.921567409,1.766974987,0.271746811,DB1396110041349_,1.302884488,0.239609189,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,51947,DB01373,10042212,79,22641,6,7375,4.09604033854889e-05,4.288814083,1.883972199,12.04358464,0.000372284,DB0137310042212_,7.895854599,1.456010257,female,10042212,Stress fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,51949,DB00169,10047626,111,38580,31,18144,0.008861435,1.683947145,1.121594394,2.596453548,0.032314485,DB0016910047626_,3.432239686,0.521140529,NA,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,51951,DB01373,10047626,73,22647,10,7371,0.006898346,2.376022604,1.220389508,5.164818201,0.026495656,DB0137310047626_,3.630774501,0.865427915,NA,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,calcium,DB01373
,51953,DB00169,10062132,47,38644,6,18169,0.000954515,3.68255677,1.571067422,10.54458831,0.005302076,DB0016910062132_,5.239656807,1.303607285,female,10062132,Tooth extraction,10042613,Surgical and medical procedures,Surg,cholecalciferol,DB00169
,51958,DB01373,10062189,53,22667,6,7375,0.00925024,2.874077496,1.235753323,8.185210272,0.033444643,DB0137310062189_,3.397863661,1.055731752,female,10062189,Vitamin D decreased,10022891,Investigations,Inv,calcium,DB01373
,51993,DB00635,10036790,184,32869,104,23690,0.048268185,1.275149171,0.996631803,1.638822209,0.121829196,DB0063510036790_,2.105135247,0.243063169,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,51994,DB01222,10036790,82,9192,42,5363,0.514414416,1.139114605,0.774791997,1.696716119,0.67437403,DB0122210036790_,0.393970382,0.130251298,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,51995,DB01409,10036790,79,5952,35,3931,0.0539328,1.490672916,0.987087565,2.292335221,0.132370666,DB0140910036790_,2.022149216,0.39922764,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,51996,DB00635,10069327,102,32951,50,23744,0.026118843,1.469982467,1.037629624,2.10629099,0.075998649,DB0063510069327_,2.577039713,0.385250474,NA,10069327,Product quality issue,10077536,Product issues,Prod,prednisone,DB00635
,51998,DB00381,10021425,45,29315,16,22871,0.006275747,2.194196807,1.216277919,4.160055334,0.024549148,DB0038110021425_,3.707078113,0.78581606,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,amlodipine,DB00381
,51999,DB00635,10021425,64,32989,21,23773,0.001293518,2.19617237,1.323095331,3.787289245,0.006799345,DB0063510021425_,4.990929034,0.786716013,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,prednisone,DB00635
,52001,DB00787,10021425,42,16958,35,17213,0.425259188,1.218035464,0.758787741,1.966167666,0.594033999,DB0078710021425_,0.520818724,0.197239286,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,acyclovir,DB00787
,52010,DB00864,10024715,21,6848,39,8353,0.152092001,0.656819364,0.366718219,1.145546057,0.28686295,DB0086410024715_,1.248750704,-0.420346239,NA,10024715,Liver transplant rejection,10021428,Immune system disorders,Immun,tacrolimus,DB00864
,52013,DB00559,10006451,161,9498,23,3283,1.73926311476023e-05,2.419256301,1.553901125,3.933305202,0.000176512,DB0055910006451_,8.64212338,0.883460179,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,bosentan,DB00559
,52014,DB01409,10006451,174,5857,42,3924,2.07756361769475e-10,2.775295539,1.96628064,3.996029262,6.44351146797717e-09,DB0140910006451_,18.86019219,1.020757242,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,tiotropium,DB01409
,52015,DB00559,10017577,68,9591,21,3285,0.807162251,1.109065713,0.67020453,1.908279646,0.895805598,DB0055910017577_,0.110031857,0.103517961,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,52016,DB01409,10017577,62,5969,27,3939,0.081274473,1.515286848,0.947980131,2.481994389,0.180523429,DB0140910017577_,1.711894708,0.41560476,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,52019,DB00635,10024968,50,33003,22,23772,0.055867905,1.637023842,0.972926316,2.839632467,0.135845317,DB0063510024968_,1.996238414,0.492879863,NA,10024968,Lower respiratory tract infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,52022,DB00472,10035664,235,10524,109,4203,0.205261346,0.861056581,0.681179298,1.093932306,0.355479787,DB0047210035664_,1.034286889,-0.149595062,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,fluoxetine,DB00472
,52025,DB00028,10020642,81,13377,43,5572,0.199818811,0.784623482,0.534841631,1.165357283,0.348802397,DB0002810020642_,1.053249716,-0.242551317,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,human immunoglobulin g,DB00028
,52026,DB00073,10020642,41,7365,50,6357,0.113534033,0.707795458,0.455984965,1.093132967,0.231430262,DB0007310020642_,1.463476695,-0.345600128,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,rituximab,DB00073
,52029,DB00028,10028372,63,13395,44,5571,0.01035926,0.595513054,0.398246061,0.897412713,0.036614355,DB0002810028372_,3.30731491,-0.51833197,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,human immunoglobulin g,DB00028
,52040,DB00203,10013710,31,13847,56,8882,2.4309094016966e-06,0.355097789,0.22110718,0.560823992,3.14064652856206e-05,DB0020310013710_,10.36849679,-1.035362065,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,52041,DB00758,10013710,75,8225,105,9969,0.366799018,0.865749348,0.634010145,1.177300395,0.536445484,DB0075810013710_,0.622790336,-0.144159848,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,52042,DB00820,10013710,24,11891,34,5782,6.07303610435475e-05,0.343257845,0.194544397,0.596732504,0.000521155,DB0082010013710_,7.559463197,-1.069273379,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,52043,DB00203,10061026,61,13817,46,8892,0.428224068,0.853420403,0.571941502,1.281143321,0.596732651,DB0020310061026_,0.516286087,-0.158503001,NA,10061026,Cardiac operation,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,52044,DB00264,10061026,20,29587,45,24847,0.000151305,0.373247575,0.208714514,0.645415883,0.001135813,DB0026410061026_,6.780406149,-0.985513338,NA,10061026,Cardiac operation,10042613,Surgical and medical procedures,Surg,metoprolol,DB00264
,52064,DB00028,10030095,31,13427,19,5596,0.213063186,0.680011547,0.371846315,1.275154266,0.365118221,DB0002810030095_,1.007534084,-0.3856455,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,52071,DB01101,10037377,38,7551,17,3891,0.671402785,1.151812549,0.633627581,2.1792648,0.80062707,DB0110110037377_,0.222360021,0.141336831,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,capecitabine,DB01101
,52075,DB00264,10008479,487,29120,391,24501,0.516437168,1.047969476,0.914450087,1.201514782,0.676073958,DB0026410008479_,0.391452804,0.04685446,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,52077,DB00264,10018964,71,29536,87,24805,0.020156608,0.685384173,0.493523263,0.949089816,0.062155848,DB0026410018964_,2.778110378,-0.377775762,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,52081,DB00264,10042458,64,29543,43,24849,0.285469906,1.25188271,0.837144374,1.888344317,0.450097564,DB0026410042458_,0.798290911,0.224648586,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,52096,DB00338,10001053,142,33532,102,22170,0.555392139,0.920439935,0.708260956,1.199721209,0.708750207,DB0033810001053_,0.344252133,-0.082903533,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,52098,DB00635,10001053,144,32909,140,23654,0.011325188,0.73932009,0.581413504,0.940324257,0.039300622,DB0063510001053_,3.236514945,-0.302024313,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,52102,DB00863,10001053,46,10627,31,5809,0.403180227,0.811147014,0.502787176,1.324825188,0.572931978,DB0086310001053_,0.556988282,-0.209305966,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,52104,DB01104,10001053,51,15412,25,7261,0.902126058,0.961109985,0.584061656,1.620164816,0.957195726,DB0110410001053_,0.043747388,-0.039666428,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,52110,DB00395,10035664,68,2116,21,715,0.804653284,1.094123978,0.65678048,1.893750628,0.894419007,DB0039510035664_,0.111580926,0.089954023,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,carisoprodol,DB00395
,52111,DB00863,10035664,379,10294,261,5579,0.00410584,0.787021992,0.668106188,0.928117574,0.017446168,DB0086310035664_,4.048635237,-0.239499086,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ranitidine,DB00863
,52112,DB00993,10035664,106,3143,38,1581,0.087657249,1.40307617,0.954905533,2.100246707,0.19125681,DB0099310035664_,1.654138197,0.338667091,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,azathioprine,DB00993
,52114,DB01156,10035664,220,13402,133,6195,0.017861764,0.76459738,0.612374422,0.957655067,0.056541996,DB0115610035664_,2.872771629,-0.268405884,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,bupropion,DB01156
,52115,DB01611,10035664,294,11619,80,2281,0.013381857,0.721481823,0.55925016,0.939647672,0.044910891,DB0161110035664_,3.103074943,-0.326448095,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,hydroxychloroquine,DB01611
,52138,DB01409,10033371,174,5857,71,3895,0.000448245,1.629680388,1.225831032,2.18587457,0.002819171,DB0140910033371_,5.871312458,0.488383914,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,52152,DB00158,10024774,46,16769,21,8083,0.896687664,1.055851351,0.616996651,1.864096422,0.956301489,DB0015810024774_,0.044682051,0.054347409,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,folic acid,DB00158
,52163,DB00465,10035664,40,2064,28,855,0.042889956,0.591890795,0.35359204,1.003191345,0.111493102,DB0046510035664_,2.193792557,-0.52443313,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ketorolac,DB00465
,52164,DB00542,10035664,51,1635,42,1382,0.916310795,1.026382003,0.664318327,1.593259023,0.962623242,DB0054210035664_,0.038093178,0.02604,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,benazepril,DB00542
,52165,DB00715,10035664,138,4705,76,2211,0.297796149,0.853316487,0.637217329,1.149819769,0.463691238,DB0071510035664_,0.768536384,-0.158624772,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,paroxetine,DB00715
,52166,DB00959,10035664,286,7792,197,4805,0.252257906,0.895259704,0.74134048,1.082861561,0.41236351,DB0095910035664_,0.885850013,-0.11064143,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,52172,DB00158,10038435,100,16715,66,8038,0.055477416,0.728600803,0.528033386,1.011114941,0.135127081,DB0015810038435_,2.001539606,-0.316629293,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,folic acid,DB00158
,52176,DB00956,10038435,39,5775,33,3434,0.143121396,0.702797197,0.429809055,1.155474604,0.274214294,DB0095610038435_,1.293845384,-0.352686912,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,hydrocodone,DB00956
,52177,DB00959,10038435,68,8010,53,4949,0.221996113,0.792742027,0.544385829,1.15973475,0.376025766,DB0095910038435_,0.978097611,-0.232257423,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,methylprednisolone,DB00959
,52179,DB00158,10038695,77,16738,62,8042,0.003493063,0.596706711,0.421090337,0.848613139,0.015301252,DB0015810038695_,4.179820599,-0.516329558,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,52183,DB00641,10038695,74,14050,92,12383,0.028913445,0.708928306,0.514320054,0.974364659,0.08228561,DB0064110038695_,2.497559029,-0.344000877,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,52186,DB00158,10040047,157,16658,129,7975,8.09946287814463e-06,0.582664594,0.457910815,0.742501723,9.0477850298356e-05,DB0015810040047_,9.310405485,-0.540143568,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,folic acid,DB00158
,52189,DB00715,10040047,32,4811,25,2262,0.063771101,0.601858677,0.344679864,1.062065933,0.150259816,DB0071510040047_,1.895389376,-0.507732617,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,paroxetine,DB00715
,52190,DB00956,10040047,27,5787,36,3431,0.001550651,0.444695981,0.259166381,0.75469735,0.007902239,DB0095610040047_,4.840609179,-0.810364419,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,hydrocodone,DB00956
,52191,DB08904,10040047,51,11559,11,3548,0.367103086,1.423067824,0.731425478,3.031407385,0.536713554,DB0890410040047_,0.622290746,0.352814981,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,52192,DB06273,10053762,176,4919,113,1297,7.75461907666284e-12,0.410742357,0.319797257,0.529206131,3.01523908920241e-10,DB0627310053762_,21.9221718,-0.88978913,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tocilizumab,DB06273
,52198,DB06724,10000081,134,7795,54,3865,0.211904267,1.230341105,0.888449712,1.724604073,0.36367756,DB0672410000081_,1.011487629,0.207291452,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,52200,DB06724,10003239,263,7666,49,3870,2.92588891409004e-12,2.709385884,1.985452243,3.763994831,1.22074587471201e-10,DB0672410003239_,22.82638889,0.996721998,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,52202,DB06724,10003549,273,7656,139,3780,0.789923611,0.969674839,0.784651779,1.202719918,0.886130966,DB0672410003549_,0.120890522,-0.030794481,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,52204,DB00927,10011224,195,7302,92,4924,0.005009195,1.429258377,1.106714754,1.857041466,0.020492871,DB0092710011224_,3.887678207,0.357155693,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,52205,DB06724,10011224,188,7741,71,3848,0.052748161,1.316248928,0.993706322,1.759732112,0.130198649,DB0672410011224_,2.038693924,0.27478597,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,52207,DB00028,10013950,39,13419,13,5602,0.544741969,1.252369124,0.653826738,2.559202784,0.699660037,DB0002810013950_,0.357160723,0.225037057,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,human immunoglobulin g,DB00028
,52208,DB00073,10013950,61,7345,23,6384,0.000405002,2.304962869,1.404104028,3.907319205,0.002590142,DB0007310013950_,5.956042468,0.835064568,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,rituximab,DB00073
,52209,DB00635,10013950,187,32866,135,23659,1,0.997142746,0.794363647,1.254397418,1,DB0063510013950_,0,-0.002861343,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,52210,DB00927,10013950,68,7429,35,4981,0.226167817,1.302620619,0.852738468,2.02162493,0.381041635,DB0092710013950_,0.964846633,0.264378096,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,52211,DB06724,10013950,92,7837,32,3887,0.084976035,1.425904165,0.942360186,2.208280315,0.186755441,DB0672410013950_,1.677955319,0.354806114,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,52214,DB00316,10014080,51,65423,25,36928,0.633313498,1.151460586,0.70026736,1.939737785,0.771948665,DB0031610014080_,0.258837227,0.141031211,NA,10014080,Ecchymosis,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,52217,DB00927,10015090,70,7427,33,4983,0.106129996,1.423146208,0.926475571,2.226594759,0.220401907,DB0092710015090_,1.512302548,0.35287006,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,52218,DB06724,10015090,47,7882,23,3896,1,1.010075329,0.600183664,1.745624854,1,DB0672410015090_,0,0.010024911,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,52219,DB00002,10016256,28,388,46,763,0.526748551,1.196800515,0.708497848,1.990429966,0.684476254,DB0000210016256_,0.379101326,0.179651759,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cetuximab,DB00002
,52222,DB00927,10017885,96,7401,29,4987,7.21096333565418e-05,2.230462161,1.456499834,3.511332479,0.000601906,DB0092710017885_,7.415409419,0.802208811,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,52226,DB00927,10018836,31,7466,21,4995,1,0.987618172,0.548944307,1.810516353,1,DB0092710018836_,0,-0.012459121,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,52229,DB06724,10019211,335,7594,85,3834,3.69168808932001e-09,1.989687652,1.558459422,2.563431188,9.1113635143452e-08,DB0672410019211_,16.21115837,0.687977668,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,52231,DB00635,10020642,185,32868,116,23678,0.265709433,1.14887427,0.905443093,1.462808082,0.427794466,DB0063510020642_,0.849112418,0.138782567,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,52232,DB00927,10020642,42,7455,52,4964,0.00297894,0.537854928,0.348822665,0.824948837,0.013430778,DB0092710020642_,4.310206344,-0.620166406,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,famotidine,DB00927
,52233,DB06724,10020642,49,7880,31,3888,0.284661908,0.779933338,0.486587277,1.267452463,0.4492193,DB0672410020642_,0.800244092,-0.248546828,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,calcium carbonate,DB06724
,52244,DB00316,10023644,113,65361,45,36908,0.04686162,1.417967527,0.99516912,2.05097778,0.119200047,DB0031610023644_,2.126952133,0.349224527,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,acetaminophen,DB00316
,52245,DB00635,10023644,44,33009,21,23773,0.13169317,1.50897312,0.878006426,2.67229631,0.258170865,DB0063510023644_,1.354133644,0.411429367,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,prednisone,DB00635
,52249,DB00073,10028334,54,7352,29,6378,0.036400153,1.615320901,1.009067824,2.634666573,0.098358059,DB0007310028334_,2.319140799,0.479533637,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,rituximab,DB00073
,52250,DB06724,10028334,134,7795,34,3885,0.000260079,1.96416941,1.336578349,2.95847615,0.001794921,DB0672410028334_,6.322793996,0.675069464,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,52252,DB00028,10028411,98,13360,42,5573,0.925865473,0.973328895,0.670519446,1.434576656,0.968399911,DB0002810028411_,0.032110146,-0.027033232,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,human immunoglobulin g,DB00028
,52253,DB00927,10028411,63,7434,40,4976,0.840407086,1.054239632,0.69703453,1.611149667,0.918392727,DB0092710028411_,0.085130173,0.052819779,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,famotidine,DB00927
,52254,DB00002,10028813,33,383,55,754,0.484227546,1.181023514,0.72956726,1.887042755,0.648391292,DB0000210028813_,0.433260919,0.166381447,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cetuximab,DB00002
,52256,DB00028,10035528,38,13420,24,5591,0.124136352,0.659659171,0.385165697,1.150753101,0.247292003,DB0002810035528_,1.397185442,-0.416031984,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,human immunoglobulin g,DB00028
,52257,DB00927,10035528,99,7398,71,4945,0.693735492,0.932033495,0.678667222,1.285482722,0.815602702,DB0092710035528_,0.203827928,-0.070386526,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,famotidine,DB00927
,52258,DB06724,10035528,107,7822,69,3850,0.089895607,0.763315092,0.557303702,1.051277712,0.195055806,DB0672410035528_,1.634469576,-0.270084369,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,calcium carbonate,DB06724
,52260,DB00028,10039101,40,13418,18,5597,0.774248199,0.926953405,0.518787141,1.719415677,0.876844133,DB0002810039101_,0.13142603,-0.075851979,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human immunoglobulin g,DB00028
,52262,DB00927,10039101,60,7437,26,4990,0.076665653,1.548338246,0.960692464,2.560059095,0.172656187,DB0092710039101_,1.756453022,0.437182257,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,52263,DB06724,10039101,72,7857,10,3909,1.71699426854293e-05,3.581756482,1.836982299,7.793192772,0.000174521,DB0672410039101_,8.653464067,1.275853318,female,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,52265,DB00028,10040753,1217,12241,325,5290,1.18894132962217e-14,1.618213708,1.424442715,1.842301587,6.93703059913844e-13,DB0002810040753_,27.99673239,0.481322892,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,52266,DB00927,10040753,104,7393,27,4989,2.39988483231109e-06,2.599144555,1.685545286,4.136366943,3.10514264421841e-05,DB0092710040753_,10.37986581,0.955182374,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,famotidine,DB00927
,52267,DB06724,10040753,133,7796,33,3886,0.000174108,2.00884398,1.360482245,3.043420539,0.001282939,DB0672410040753_,6.658601433,0.697559422,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,52271,DB00316,10041232,75,65399,32,36921,0.191961305,1.323160317,0.863694416,2.069418072,0.339115728,DB0031610041232_,1.081413851,0.280023054,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,52275,DB00028,10043071,37,13421,41,5574,2.66040600277207e-05,0.374821671,0.233425865,0.600016031,0.000254796,DB0002810043071_,8.275047196,-0.98130491,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,human immunoglobulin g,DB00028
,52276,DB00635,10043071,240,32813,162,23632,0.542922336,1.066977576,0.869880461,1.311374921,0.698118538,DB0063510043071_,0.359366365,0.064829956,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,prednisone,DB00635
,52277,DB00927,10043071,60,7437,45,4971,0.617284421,0.891229728,0.594395531,1.344699135,0.758352821,DB0092710043071_,0.276606538,-0.115153053,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,famotidine,DB00927
,52278,DB06724,10043071,33,7896,28,3891,0.04005517,0.580790417,0.339797288,0.999186103,0.105798135,DB0672410043071_,2.246222391,-0.543365315,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,calcium carbonate,DB06724
,52282,DB00635,10043224,63,32990,24,23770,0.006485352,1.891339071,1.164639989,3.166271343,0.02519472,DB0063510043224_,3.681120829,0.637285081,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,52288,DB00316,10044016,52,65422,30,36923,0.908958511,0.97825033,0.612434681,1.588625748,0.95913476,DB0031610044016_,0.041723693,-0.021989681,NA,10044016,Tooth abscess,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,52295,DB00316,10044055,76,65398,32,36921,0.192232168,1.340822781,0.876121083,2.095253605,0.339468744,DB0031610044055_,1.0803734,0.293283441,NA,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,52299,DB00927,10047700,347,7150,126,4890,5.41280487699439e-10,1.883385395,1.526472997,2.335754332,1.58083973546442e-08,DB0092710047700_,17.96272456,0.633070899,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,52301,DB00028,10050584,113,13345,26,5589,0.004898669,1.820156446,1.178447266,2.908982028,0.020136291,DB0002810050584_,3.905231554,0.598922457,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,human immunoglobulin g,DB00028
,52302,DB00927,10050584,57,7440,23,4993,0.039487477,1.663100003,1.006986479,2.832387802,0.104629873,DB0092710050584_,2.257326177,0.508683332,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,famotidine,DB00927
,52303,DB06724,10050584,84,7845,24,3895,0.01768483,1.737657853,1.090821761,2.865790556,0.056103457,DB0672410050584_,2.880557852,0.552538145,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium carbonate,DB06724
,52306,DB06724,10060800,53,7876,15,3904,0.053227542,1.75133899,0.971081764,3.350178627,0.131074194,DB0672410060800_,2.031991747,0.560380633,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,calcium carbonate,DB06724
,52308,DB00028,10068319,84,13374,23,5592,0.07132401,1.527067768,0.95215454,2.541497628,0.163576617,DB0002810068319_,1.810473794,0.423349405,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human immunoglobulin g,DB00028
,52309,DB00073,10068319,38,7368,36,6371,0.726741911,0.912729657,0.562428,1.483742516,0.84015137,DB0007310068319_,0.174173201,-0.091315546,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rituximab,DB00073
,52310,DB00927,10068319,55,7442,19,4997,0.01206459,1.943596641,1.133959713,3.472331364,0.04131289,DB0092710068319_,3.186580717,0.664540196,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,52311,DB06724,10068319,69,7860,20,3899,0.03193668,1.711322874,1.026092123,2.977520108,0.088967796,DB0672410068319_,2.419480819,0.537266682,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,52315,DB00316,10070488,51,65423,18,36935,0.102368898,1.599570152,0.918624494,2.909777453,0.214549016,DB0031610070488_,1.539217053,0.469734938,NA,10070488,Upper-airway cough syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,52316,DB00635,10070488,43,33010,22,23772,0.209628289,1.407547455,0.823365618,2.471436065,0.360748957,DB0063510070488_,1.019572972,0.341848796,NA,10070488,Upper-airway cough syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,52330,DB00399,10013911,46,6946,29,4969,0.639596408,1.134684424,0.696718892,1.875916713,0.776669665,DB0039910013911_,0.25274016,0.126354571,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,zoledronic acid,DB00399
,52333,DB00399,10033433,75,6917,25,4973,0.000697004,2.156716772,1.35327254,3.546175212,0.004076919,DB0039910033433_,5.502413697,0.768587052,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,52336,DB00060,10037377,43,9465,22,2443,0.012867154,0.504495274,0.294570831,0.887396444,0.04351386,DB0006010037377_,3.134675769,-0.684196808,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,interferon beta-1a,DB00060
,52337,DB00060,10050256,49,9459,15,2450,0.537889237,0.846091114,0.465714698,1.627436864,0.693961204,DB0006010050256_,0.365339222,-0.167128226,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,52340,DB00016,10008479,56,2706,28,2262,0.027093522,1.671672326,1.040050938,2.743030658,0.078219915,DB0001610008479_,2.548230996,0.513824518,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,52341,DB00958,10008479,71,4523,41,2544,0.921074807,0.974000081,0.651850265,1.47238364,0.965021878,DB0095810008479_,0.035604506,-0.026343892,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,52343,DB09140,10008479,285,3456,81,1717,8.04956681890391e-06,1.747899226,1.351229921,2.281405594,9.00161088427523e-05,DB0914010008479_,9.315521917,0.558414624,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,52344,DB01112,10011906,34,1111,35,544,0.002701875,0.475871326,0.284533599,0.795149972,0.012412147,DB0111210011906_,4.389079712,-0.742607785,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cefuroxime,DB01112
,52354,DB00016,10033425,58,2704,22,2268,0.001380536,2.210889785,1.327754013,3.806345402,0.007182066,DB0001610033425_,4.936168234,0.793395052,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,erythropoietin,DB00016
,52355,DB01222,10017577,103,9171,33,5372,0.002271471,1.828209313,1.222594545,2.798361449,0.010791798,DB0122210017577_,4.528968866,0.603336971,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,52357,DB00820,10047461,85,11830,41,5775,1,1.012055295,0.6883287,1.50931349,1,DB0082010047461_,0,0.011983208,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,tadalafil,DB00820
,52359,DB06403,10047461,77,21394,17,6644,0.225285753,1.406593994,0.823396679,2.539768588,0.380152533,DB0640310047461_,0.967182703,0.341171175,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,52360,DB00060,10002034,50,9458,9,2456,0.418608123,1.442584661,0.701098282,3.341411648,0.587616262,DB0006010002034_,0.53168116,0.366436408,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,interferon beta-1a,DB00060
,52364,DB00480,10001480,330,67098,304,67358,0.28274887,1.089710818,0.929309889,1.27818357,0.446879564,DB0048010001480_,0.805466151,0.085912357,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,52369,DB00635,10009825,33,33020,18,23776,0.395280916,1.320081653,0.721833979,2.490594335,0.564978732,DB0063510009825_,0.570967192,0.277693593,NA,10009825,Coccidioidomycosis,10021881,Infections and infestations,Infec,prednisone,DB00635
,52371,DB00028,10027201,148,13310,37,5578,0.004415167,1.676293095,1.160688267,2.476510819,0.0184915,DB0002810027201_,3.990444133,0.516584864,NA,10027201,Meningitis aseptic,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,52376,DB00091,10011224,89,5421,44,2626,0.925823332,0.979823354,0.673210719,1.444516429,0.968394368,DB0009110011224_,0.032115869,-0.020382975,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclosporine,DB00091
,52377,DB00196,10011224,109,4974,45,3240,0.009775693,1.577721806,1.101737757,2.292124787,0.034957363,DB0019610011224_,3.353626172,0.455981911,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluconazole,DB00196
,52378,DB08895,10011224,756,27358,122,6524,4.24169369885425e-05,1.477690702,1.216533702,1.80762622,0.000383731,DB0889510011224_,7.865569876,0.390480533,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,52380,DB00091,10039073,72,5438,6,2664,2.84509581080261e-07,5.878231194,2.568039097,16.56565568,4.66521168976585e-06,DB0009110039073_,12.27537735,1.771255899,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclosporine,DB00091
,52382,DB00788,10039073,143,9213,24,5037,2.2435252424235e-09,3.257367461,2.100480245,5.25808878,5.79568167047683e-08,DB0078810039073_,16.66356764,1.180919342,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,52383,DB01050,10039073,141,17967,30,9341,2.06676387674314e-06,2.443450045,1.636889827,3.758249322,2.72783773538506e-05,DB0105010039073_,10.50941621,0.893410994,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,52390,DB00091,10047899,61,5449,10,2660,0.00051217,2.977479549,1.510911514,6.528880076,0.003148727,DB0009110047899_,5.760756969,1.091077154,female,10047899,Weight increased,10022891,Investigations,Inv,cyclosporine,DB00091
,52391,DB00158,10047899,241,16574,82,8022,0.00587871,1.422501526,1.101132041,1.853494298,0.023294576,DB0015810047899_,3.759534715,0.35241696,NA,10047899,Weight increased,10022891,Investigations,Inv,folic acid,DB00158
,52392,DB00196,10047899,69,5014,9,3276,7.07635769219889e-08,5.008457896,2.48645995,11.4252951,1.32385809209571e-06,DB0019610047899_,13.53496029,1.611128063,female,10047899,Weight increased,10022891,Investigations,Inv,fluconazole,DB00196
,52393,DB00788,10047899,154,9202,47,5014,0.000340552,1.785290563,1.277674435,2.535461071,0.002242053,DB0078810047899_,6.100363248,0.579581183,NA,10047899,Weight increased,10022891,Investigations,Inv,naproxen,DB00788
,52396,DB00196,10068319,36,5047,16,3269,0.254541248,1.457287755,0.786817717,2.817511945,0.415230976,DB0019610068319_,0.878920345,0.376577006,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluconazole,DB00196
,52397,DB01050,10068319,134,17974,37,9334,0.000467281,1.880689277,1.297119397,2.787237818,0.002919186,DB0105010068319_,5.836450405,0.631638346,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,52399,DB01609,10025482,50,1534,22,1321,0.008316312,1.9567222,1.156160964,3.412312191,0.03070791,DB0160910025482_,3.48323501,0.671270726,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,deferasirox,DB01609
,52400,DB08877,10025482,92,3197,71,3158,0.131822583,1.279915986,0.925045528,1.777170968,0.258357126,DB0887710025482_,1.35341244,0.24679444,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,52418,DB00341,10016173,265,11140,91,4977,0.031703864,1.300963217,1.019036485,1.673592607,0.088442614,DB0034110016173_,2.425401364,0.263104926,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,52419,DB00697,10016173,339,5757,85,1721,0.171426154,1.192214163,0.931215943,1.540099163,0.312791606,DB0069710016173_,1.162218105,0.175812219,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,tizanidine,DB00697
,52420,DB00956,10016173,185,5629,83,3384,0.029312154,1.339914687,1.024943143,1.763964677,0.083181642,DB0095610016173_,2.486728601,0.292605945,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocodone,DB00956
,52421,DB01222,10016173,199,9075,105,5300,0.43486397,1.10686918,0.867229595,1.419322893,0.603302453,DB0122210016173_,0.505336628,0.101535471,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,budesonide,DB01222
,52422,DB01233,10016173,86,3335,29,1697,0.057959142,1.508878084,0.975777035,2.394727223,0.139623623,DB0123310016173_,1.968804886,0.411366384,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,metoclopramide,DB01233
,52424,DB00331,10023469,42,24904,21,20731,0.057840277,1.664850903,0.963633523,2.960396366,0.139396845,DB0033110023469_,1.970430416,0.509735572,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,metformin,DB00331
,52426,DB00381,10023469,56,29304,21,22866,0.003789717,2.080755341,1.239735335,3.619174191,0.016331293,DB0038110023469_,4.114672197,0.732730973,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,amlodipine,DB00381
,52430,DB00999,10023469,47,21383,18,12221,0.157371581,1.492308118,0.850070902,2.731452042,0.294036964,DB0099910023469_,1.224049792,0.400323994,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,hydrochlorothiazide,DB00999
,52440,DB00928,10028533,10,825,49,1237,0.00022098,0.306142737,0.137439249,0.616206957,0.001566676,DB0092810028533_,6.458799316,-1.183703825,male,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,azacitidine,DB00928
,52442,DB00193,10040070,44,19276,36,8666,0.010493972,0.549522206,0.345409149,0.879325599,0.036992429,DB0019310040070_,3.297042017,-0.598706095,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,tramadol,DB00193
,52443,DB00196,10040070,49,5034,41,3244,0.233164545,0.770194303,0.496989241,1.198980267,0.38974436,DB0019610040070_,0.942264243,-0.261112454,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,fluconazole,DB00196
,52445,DB00761,10040070,83,15224,71,8554,0.011303757,0.656822846,0.472134316,0.915889871,0.039234021,DB0076110040070_,3.238211014,-0.420340938,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,52446,DB00787,10040070,63,16937,89,17159,0.050704188,0.717153185,0.510530568,1.002221569,0.126303979,DB0078710040070_,2.069063744,-0.332465813,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,acyclovir,DB00787
,52447,DB00904,10040070,100,22969,91,14365,0.011106018,0.687289056,0.511753721,0.923973938,0.038695875,DB0090410040070_,3.252022284,-0.375000325,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,ondansetron,DB00904
,52454,DB00557,10035664,146,5841,75,2992,1,0.997162649,0.74696004,1.340365472,1,DB0055710035664_,0,-0.002841384,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,hydroxyzine,DB00557
,52455,DB01142,10035664,39,1701,18,766,1,0.975709537,0.54095117,1.824425817,1,DB0114210035664_,0,-0.024590342,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,doxepin,DB01142
,52487,DB00115,10029331,379,18046,276,10196,0.001760741,0.775876134,0.661326516,0.911119998,0.00875458,DB0011510029331_,4.73817829,-0.253762393,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,52488,DB00196,10029331,75,5008,47,3238,0.925696002,1.031751889,0.705027426,1.523250424,0.968288692,DB0019610029331_,0.032225001,0.031258221,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,fluconazole,DB00196
,52490,DB00285,10029331,65,10886,22,3696,1,1.003123227,0.609282663,1.711263836,1,DB0028510029331_,0,0.00311836,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,52491,DB00836,10029331,103,5432,51,4024,0.021102304,1.496053619,1.056666671,2.141348687,0.064496985,DB0083610029331_,2.741136806,0.40283072,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,52494,DB14513,10029331,120,7057,73,3491,0.165909398,0.813215899,0.601097553,1.106494429,0.305339161,DB1451310029331_,1.186332116,-0.206758646,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,52495,DB00268,10035664,130,2845,70,1475,0.819211846,0.962872513,0.709430229,1.315870933,0.903627158,DB0026810035664_,0.10133844,-0.037834261,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ropinirole,DB00268
,52496,DB00285,10035664,219,10732,75,3643,0.946044597,0.991200605,0.75702356,1.309902201,0.984569605,DB0028510035664_,0.015550682,-0.008838338,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,venlafaxine,DB00285
,52497,DB00972,10035664,84,2420,53,1126,0.093192105,0.737480339,0.512743341,1.068764136,0.200413539,DB0097210035664_,1.607372353,-0.30451585,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,azelastine,DB00972
,52504,DB00996,10042682,140,38813,60,22365,0.055963761,1.344517414,0.986353206,1.851921564,0.136034309,DB0099610042682_,1.994848154,0.296035149,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,52505,DB08910,10042682,90,16654,49,17439,0.000230214,1.923260847,1.342428258,2.784366399,0.001620778,DB0891010042682_,6.424849256,0.654022103,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,52507,DB14513,10042682,43,7134,15,3549,0.265124337,1.42605618,0.775410117,2.767425231,0.427074809,DB1451310042682_,0.850796085,0.354912718,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,52528,DB00374,10017412,45,17671,13,5711,0.878370374,1.118710602,0.59256237,2.262175055,0.948638561,DB0037410017412_,0.052727416,0.112176774,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,treprostinil,DB00374
,52529,DB00820,10017412,47,11868,13,5803,0.07322026,1.767734319,0.939989448,3.564477867,0.166884418,DB0082010017412_,1.790453817,0.569698681,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,tadalafil,DB00820
,52533,DB00331,10013887,46,24900,45,20707,0.461721323,0.850091491,0.550973343,1.312314504,0.628940221,DB0033110013887_,0.463719066,-0.162411299,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,metformin,DB00331
,52534,DB00338,10013887,72,33602,44,22228,0.705153556,1.082480186,0.733507197,1.613433924,0.823292569,DB0033810013887_,0.19444365,0.079254877,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,52535,DB00476,10013887,51,17206,19,6158,0.892108351,0.960674025,0.556947455,1.724401766,0.955096007,DB0047610013887_,0.045943412,-0.040120131,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,52536,DB00656,10013887,31,11982,29,6590,0.042681847,0.587912095,0.342454127,1.012107398,0.111072952,DB0065610013887_,2.197568066,-0.531177841,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,52537,DB00682,10013887,35,19424,27,16337,0.799142468,1.09030932,0.640903647,1.873764102,0.891516235,DB0068210013887_,0.114831631,0.086461435,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,52538,DB00758,10013887,36,8264,34,10040,0.335929722,1.286347936,0.781614837,2.121113956,0.505042626,DB0075810013887_,0.683112446,0.251807146,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,52544,DB00193,10043414,42,19278,22,8680,0.589142422,0.859592358,0.501280354,1.512941096,0.735920569,DB0019310043414_,0.306633089,-0.151297004,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,52545,DB00230,10043414,32,19642,18,8633,0.44232167,0.781343512,0.425285718,1.479335992,0.610432204,DB0023010043414_,0.493588041,-0.24674039,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,52547,DB00331,10043414,53,24893,33,20719,0.195328825,1.336749798,0.849268697,2.132256249,0.343437451,DB0033110043414_,1.068750278,0.290241144,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,52548,DB00338,10043414,71,33603,34,22238,0.134429579,1.381956728,0.905647629,2.146279245,0.26185575,DB0033810043414_,1.339961501,0.323500414,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,52549,DB00476,10043414,48,17209,18,6159,0.888839245,0.954383252,0.544590075,1.744701596,0.953896257,DB0047610043414_,0.047200359,-0.046689956,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,52550,DB00656,10043414,40,11973,25,6594,0.606310958,0.881193024,0.521115233,1.516998419,0.749302055,DB0065610043414_,0.288613098,-0.126478581,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,52552,DB00722,10043414,48,25355,36,25996,0.157605754,1.367027299,0.868696008,2.168737864,0.294273148,DB0072210043414_,1.223246869,0.312638527,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,52558,DB00193,10044390,40,19280,19,8683,0.888136096,0.948135371,0.536086441,1.73427658,0.953646495,DB0019310044390_,0.047462226,-0.05325799,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,52560,DB00476,10044390,36,17221,21,6156,0.096120767,0.612821022,0.347921311,1.105739604,0.204951073,DB0047610044390_,1.584983996,-0.489682356,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,52562,DB00722,10044390,66,25337,78,25954,0.405015956,0.866762189,0.6145976,1.219266592,0.574720998,DB0072210044390_,0.553870576,-0.142990632,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,52566,DB00588,10020100,51,16473,22,8446,0.537964079,1.188544882,0.707439608,2.059499029,0.694023697,DB0058810020100_,0.365249174,0.17272977,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,52581,DB00203,10063829,81,13797,29,8909,0.005911272,1.803516371,1.165884382,2.862144816,0.023393222,DB0020310063829_,3.755308965,0.589738299,NA,10063829,Device malfunction,10077536,Product issues,Prod,sildenafil,DB00203
,52582,DB00480,10003899,39,67389,47,67615,0.450461598,0.832572326,0.530193906,1.300772368,0.618173855,DB0048010003899_,0.480985542,-0.183235183,NA,10003899,B-cell lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,52597,DB00332,10016322,39,2645,14,1642,0.08772105,1.729151195,0.915079104,3.458798799,0.191372187,DB0033210016322_,1.653535126,0.547630649,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ipratropium,DB00332
,52598,DB00332,10025482,91,2593,34,1622,0.011394228,1.67402614,1.111433471,2.57387251,0.039511515,DB0033210025482_,3.23116312,0.515231587,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ipratropium,DB00332
,52599,DB00294,10013968,76,14295,6,162,0.000369053,0.143623164,0.061741133,0.409383254,0.002398455,DB0029410013968_,6.032930348,-1.940562325,male,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etonogestrel,DB00294
,52601,DB08908,10008479,96,10577,28,3251,0.915286002,1.053788231,0.684107343,1.671256622,0.962143444,DB0890810008479_,0.03859173,0.052391511,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,52604,DB08908,10053762,84,10589,22,3257,0.566162111,1.17439354,0.725962845,1.97621316,0.717581845,DB0890810053762_,0.331868269,0.160751878,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,dimethyl fumarate,DB08908
,52634,DB00338,10045285,45,33629,19,22253,0.124509824,1.567219342,0.898028391,2.83803692,0.24782358,DB0033810045285_,1.395038157,0.449302929,NA,10045285,Ulcer,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,52635,DB00635,10045285,52,33001,31,23763,0.437119224,1.207845934,0.75950788,1.950355384,0.605628379,DB0063510045285_,0.501488717,0.188838554,NA,10045285,Ulcer,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,52637,DB00047,10001053,32,9253,34,8484,0.621862942,0.862965208,0.51505306,1.442734286,0.762106837,DB0004710001053_,0.271668527,-0.147380904,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,52638,DB00641,10001053,57,14067,46,12429,0.692834424,1.094806292,0.728780675,1.652620845,0.814954759,DB0064110001053_,0.204622678,0.090577446,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,52640,DB00736,10001053,30,10561,23,5530,0.192070223,0.682980564,0.383183688,1.232500367,0.339251138,DB0073610001053_,1.081014627,-0.381288877,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,52641,DB00959,10001053,52,8026,60,4942,0.001172129,0.533661026,0.360259775,0.788285851,0.006279544,DB0095910001053_,5.070457945,-0.627994423,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,52643,DB01137,10001053,34,7738,36,5557,0.114469424,0.678280283,0.411169086,1.116704955,0.232851482,DB0113710001053_,1.457354443,-0.38819468,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,52645,DB08931,10001053,71,6506,27,2419,0.909315743,0.977725979,0.617959522,1.588583509,0.959242524,DB0893110001053_,0.041611343,-0.022525834,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,52663,DB08931,10018964,96,6481,57,2389,0.005778185,0.620863043,0.441178664,0.880540313,0.022977247,DB0893110018964_,3.773250802,-0.476644764,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,52664,DB00047,10030095,72,9213,50,8468,0.145509425,1.323532256,0.908766671,1.940853892,0.277757098,DB0004710030095_,1.281008296,0.280304114,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,52666,DB00736,10030095,75,10516,26,5527,0.07381094,1.516059805,0.957719242,2.471292993,0.16788859,DB0073610030095_,1.784454675,0.416114736,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,52667,DB00959,10030095,38,8040,20,4982,0.590820541,1.177364494,0.667192104,2.138183859,0.737333487,DB0095910030095_,0.304714996,0.163278461,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,52669,DB01137,10030095,35,7737,34,5559,0.222399855,0.739654606,0.447399003,1.223951923,0.376491286,DB0113710030095_,0.976860377,-0.301571951,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,52694,DB00213,10038063,72,18823,59,13362,0.424914745,0.866296059,0.605019556,1.244654082,0.593679055,DB0021310038063_,0.521416417,-0.14352856,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,52695,DB00374,10038063,48,17668,19,5705,0.476326554,0.81574186,0.470189517,1.470827346,0.641685338,DB0037410038063_,0.443657223,-0.203657322,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,52696,DB00641,10038063,60,14064,61,12414,0.465696213,0.868214765,0.597150682,1.261944127,0.632519052,DB0064110038063_,0.458044937,-0.14131617,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,52701,DB06403,10038063,53,21418,19,6642,0.579791616,0.865081035,0.503359249,1.548588168,0.728446184,DB0640310038063_,0.316841528,-0.144932094,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,52702,DB08931,10038063,44,6533,14,2432,0.659905031,1.169947616,0.627928598,2.315916187,0.792289944,DB0893110038063_,0.232827864,0.156958975,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,52703,DB00047,10061822,27,9258,33,8485,0.300999874,0.749883182,0.433311001,1.287191921,0.467293608,DB0004710061822_,0.760797508,-0.287837842,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,52704,DB00374,10061822,208,17508,63,5661,0.72214245,1.067520861,0.800327977,1.440998052,0.83633743,DB0037410061822_,0.178723123,0.065339008,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,52705,DB00959,10061822,79,7999,25,4977,0.002321707,1.96606474,1.238217527,3.222830003,0.010982826,DB0095910061822_,4.511422486,0.676033951,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,52708,DB06403,10061822,140,21331,48,6613,0.547159795,0.90421071,0.646361379,1.284222105,0.701783273,DB0640310061822_,0.354130651,-0.10069286,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,52709,DB08931,10061822,80,6497,18,2428,0.052098349,1.660911145,0.984362823,2.950244812,0.128958354,DB0893110061822_,2.048265766,0.507366334,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,52716,DB00820,10009033,123,11792,60,5756,1,1.00068569,0.727899955,1.388556823,1,DB0082010009033_,0,0.000685455,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,52718,DB00820,10019974,50,11865,18,5798,0.301703357,1.357408,0.777435807,2.47450462,0.468028372,DB0082010019974_,0.759226361,0.305576999,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,tadalafil,DB00820
,52722,DB00620,10000087,70,4758,26,3106,0.015212274,1.757406988,1.103191204,2.879468154,0.049863401,DB0062010000087_,2.998468001,0.563839421,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,triamcinolone,DB00620
,52724,DB00620,10002855,87,4741,35,3097,0.01510669,1.623667399,1.081899215,2.484246029,0.049597719,DB0062010002855_,3.003810433,0.484687417,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,triamcinolone,DB00620
,52725,DB00879,10002855,14,1763,37,3675,0.548039389,0.788793248,0.392805439,1.498435994,0.702539216,DB0087910002855_,0.353054056,-0.237251035,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,emtricitabine,DB00879
,52731,DB00620,10013710,49,4779,50,3082,0.029174449,0.632064746,0.416263429,0.959264641,0.082866911,DB0062010013710_,2.490519435,-0.458763444,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,52732,DB00879,10013710,57,1720,105,3607,0.443673866,1.138385875,0.805446904,1.5951674,0.611743257,DB0087910013710_,0.491442599,0.12961136,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,emtricitabine,DB00879
,52743,DB00620,10017885,45,4783,16,3116,0.035657235,1.832138338,1.013745505,3.478783161,0.096788396,DB0062010017885_,2.335228169,0.605483775,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,triamcinolone,DB00620
,52746,DB00620,10019211,315,4513,96,3036,2.40222696576131e-12,2.207155443,1.74232209,2.816919747,1.01760734560896e-10,DB0062010019211_,23.0083968,0.791704556,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,triamcinolone,DB00620
,52748,DB00620,10022437,96,4732,44,3088,0.055006723,1.423745847,0.983451465,2.089532405,0.134341624,DB0062010022437_,2.007369292,0.353291319,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,triamcinolone,DB00620
,52749,DB00879,10022437,16,1761,56,3656,0.075241435,0.593220415,0.316672119,1.052552086,0.170236378,DB0087910022437_,1.770567349,-0.522189254,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,emtricitabine,DB00879
,52755,DB00620,10028813,307,4521,111,3021,2.32476039194212e-08,1.847985305,1.474996635,2.328803543,4.80395651746844e-07,DB0062010028813_,14.5486558,0.614096021,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,triamcinolone,DB00620
,52769,DB00620,10047899,75,4753,25,3107,0.002742506,1.960920069,1.229280485,3.226486768,0.012566332,DB0062010047899_,4.376734114,0.673413786,NA,10047899,Weight increased,10022891,Investigations,Inv,triamcinolone,DB00620
,52777,DB00563,10024855,92,46554,25,15323,0.453267674,1.211243555,0.771100341,1.968380951,0.620819177,DB0056310024855_,0.47671542,0.191647564,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,52783,DB00005,10074902,40,128042,23,42396,0.040467537,0.575846314,0.336449947,1.007656942,0.106592767,DB0000510074902_,2.238739621,-0.551914469,NA,10074902,Expired product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,52787,DB00678,10037855,34,15565,25,10699,0.792451835,0.934833544,0.541217243,1.635478621,0.887531177,DB0067810037855_,0.119311629,-0.067386794,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,52794,DB01068,10037884,38,13725,14,6826,0.378864618,1.349933912,0.714372528,2.699198513,0.54882648,DB0106810037884_,0.599972953,0.300055637,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,clonazepam,DB01068
,52795,DB01156,10037884,44,13578,12,6316,0.113572078,1.705561163,0.884727437,3.550125736,0.231485893,DB0115610037884_,1.463236343,0.533894184,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,bupropion,DB01156
,52805,DB08868,10027599,181,9021,18,2493,4.5552599415989e-06,2.778798313,1.704797012,4.805023892,5.45365554839112e-05,DB0886810027599_,9.816639338,1.022018573,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,52867,DB00005,10012318,83,127999,20,42399,0.211942249,1.374643367,0.835659138,2.365971244,0.363718996,DB0000510012318_,1.011373698,0.318194328,NA,10012318,Dental caries,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,52869,DB08877,10047942,55,3234,63,3166,0.404830432,0.854680862,0.582197061,1.251497147,0.574581814,DB0887710047942_,0.554112782,-0.157027141,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,ruxolitinib,DB08877
,52873,DB00563,10051572,104,46542,17,15331,0.005813027,2.015024475,1.199427895,3.59164047,0.02308088,DB0056310051572_,3.768750725,0.700631342,NA,10051572,Injection site discolouration,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,52877,DB00814,10061428,117,8170,44,3371,0.662734594,1.097149547,0.767599114,1.592970327,0.794417715,DB0081410061428_,0.230145866,0.092715495,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,meloxicam,DB00814
,52879,DB00921,10015535,38,5807,77,4826,4.64454637136352e-06,0.410167945,0.269984713,0.61382485,5.54728251904863e-05,DB0092110015535_,9.799617293,-0.891188582,NA,10015535,Euphoric mood,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,52883,DB00916,10028334,82,5241,16,2415,0.000920643,2.361331634,1.367278842,4.333401583,0.005148745,DB0091610028334_,5.269002301,0.859225712,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,metronidazole,DB00916
,52888,DB00916,10046571,100,5223,14,2417,3.21108175021109e-06,3.304966892,1.875745502,6.276458756,4.02111880916144e-05,DB0091610046571_,10.12136529,1.195426456,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,metronidazole,DB00916
,52890,DB00916,10055798,134,5189,15,2416,9.72725488610617e-10,4.158307925,2.426580704,7.655554799,2.70991939248861e-08,DB0091610055798_,17.42376185,1.425108243,female,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,metronidazole,DB00916
,52897,DB00921,10021576,141,5704,73,4830,0.000654243,1.635472872,1.220876732,2.206350228,0.003873579,DB0092110021576_,5.553576326,0.491931981,NA,10021576,Inadequate analgesia,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,52900,DB00904,10006784,91,22978,34,14422,0.009704957,1.679846723,1.120742808,2.571301185,0.034751538,DB0090410006784_,3.359531452,0.518702553,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,52901,DB01137,10006784,41,7731,15,5578,0.028923939,1.972025142,1.067442694,3.839504958,0.082302109,DB0113710006784_,2.497358543,0.679061005,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,52902,DB01234,10006784,97,31528,64,32824,0.004443402,1.577904793,1.138609889,2.199530532,0.018586063,DB0123410006784_,3.98534327,0.456097887,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,52903,DB00433,10013786,72,7584,38,5982,0.053307971,1.494458553,0.993710051,2.279622574,0.131198503,DB0043310013786_,2.03104381,0.401763969,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,prochlorperazine,DB00433
,52904,DB00904,10013786,125,22944,77,14379,0.942287151,1.017369947,0.759197267,1.370746283,0.981416879,DB0090410013786_,0.018757957,0.017220814,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,52906,DB01234,10013786,175,31450,116,32772,0.000160456,1.572013657,1.235457386,2.006520011,0.001194953,DB0123410013786_,6.729648418,0.452357381,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,52908,DB00904,10015967,46,23023,14,14442,0.016384478,2.061040698,1.112848692,4.06111389,0.052784166,DB0090410015967_,2.941544014,0.723211049,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,ondansetron,DB00904
,52910,DB01234,10015967,109,31516,45,32843,6.31660487326138e-08,2.524238159,1.767545326,3.658083397,1.19447452585378e-06,DB0123410015967_,13.6378042,0.925939298,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,dexamethasone,DB01234
,52918,DB06403,10020642,106,21365,19,6642,0.026321673,1.734307797,1.056776568,2.996545469,0.076466088,DB0640310020642_,2.570907929,0.55060837,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,ambrisentan,DB06403
,52935,DB08893,10033371,63,2022,18,1040,0.031386253,1.799895112,1.045666154,3.24795937,0.087750641,DB0889310033371_,2.433256107,0.587728392,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,mirabegron,DB08893
,52936,DB00188,10009887,35,7851,32,8796,0.462301198,1.225382875,0.73608951,2.046474995,0.629501748,DB0018810009887_,0.462826648,0.203253346,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,52942,DB00451,10009887,137,47134,47,15372,0.797019565,0.950642634,0.677577705,1.354663554,0.890111288,DB0045110009887_,0.116408782,-0.050617066,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,52943,DB00480,10009887,178,67250,92,67570,1.29031885340927e-07,1.94396807,1.502789792,2.52895283,2.29239817924046e-06,DB0048010009887_,12.98591205,0.664731281,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,52945,DB00997,10009887,36,5295,70,3444,5.98671371792665e-08,0.334546004,0.216857153,0.508309174,1.13576882046699e-06,DB0099710009887_,13.68820076,-1.094980878,male,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,doxorubicin,DB00997
,52957,DB00480,10014418,69,67359,30,67632,7.60459343203902e-05,2.309441243,1.483755868,3.673667541,0.000630657,DB0048010014418_,7.368748414,0.837005609,NA,10014418,Electrolyte imbalance,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,52959,DB00904,10014418,41,23028,11,14445,0.009857096,2.3379886,1.179762337,5.045970342,0.03516293,DB0090410014418_,3.347762886,0.849290987,NA,10014418,Electrolyte imbalance,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,52964,DB01234,10014418,57,31568,23,32865,7.13209525235022e-05,2.580109174,1.564127255,4.389074739,0.00059608,DB0123410014418_,7.425135865,0.947831714,NA,10014418,Electrolyte imbalance,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,52968,DB00188,10016807,44,7842,44,8784,0.594776223,1.120114002,0.719671669,1.743363024,0.74054655,DB0018810016807_,0.300366784,0.113430468,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,bortezomib,DB00188
,52971,DB00213,10016807,195,18700,78,13343,1.06784379716413e-05,1.783786577,1.363705708,2.352617429,0.000114916,DB0021310016807_,9.071307663,0.578738396,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,52973,DB00399,10016807,33,6959,23,4975,1,1.025728138,0.583578744,1.831887894,1,DB0039910016807_,0,0.025402739,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,zoledronic acid,DB00399
,52975,DB00480,10016807,248,67180,266,67396,0.45287294,0.935301464,0.783259303,1.116614821,0.620504859,DB0048010016807_,0.477221843,-0.066886381,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,52977,DB00904,10016807,142,22927,47,14409,8.84870170861245e-05,1.898757089,1.355502753,2.70211744,0.000718863,DB0090410016807_,7.237839758,0.641199508,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,52979,DB01234,10016807,157,31468,138,32750,0.161192461,1.184025325,0.935419958,1.50004463,0.299092463,DB0123410016807_,1.207002511,0.168919926,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,52981,DB00196,10021097,97,4986,87,3198,0.026737902,0.715165843,0.527982622,0.969916791,0.077428094,DB0019610021097_,2.55840559,-0.335240816,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,fluconazole,DB00196
,52985,DB00515,10021097,59,1811,86,2065,0.174726875,0.7823158,0.548457232,1.109478725,0.317087539,DB0051510021097_,1.148577396,-0.245496784,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,cisplatin,DB00515
,52986,DB00973,10021097,49,3802,54,2967,0.08908968,0.708166119,0.469557168,1.06573131,0.193795029,DB0097310021097_,1.640954229,-0.345076581,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ezetimibe,DB00973
,52987,DB01039,10021097,38,2935,51,3000,0.239982897,0.761635758,0.485277593,1.186218332,0.397849247,DB0103910021097_,0.921682123,-0.272286845,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,fenofibrate,DB01039
,52989,DB05351,10021097,34,2689,18,1113,0.443223745,0.781856349,0.42723229,1.477146761,0.611379189,DB0535110021097_,0.492037908,-0.246084252,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,dexlansoprazole,DB05351
,53002,DB00996,10054107,43,38910,12,22413,0.024548551,2.064052802,1.068972435,4.300784724,0.072500973,DB0099610054107_,2.6241553,0.72467143,NA,10054107,Nodule,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,53023,DB09072,10027091,53,6418,19,2516,0.793847239,1.093524401,0.635293181,1.960164347,0.888291402,DB0907210027091_,0.118455435,0.089405876,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium oxybate,DB09072
,53024,DB09072,10064355,75,6396,36,2499,0.338997976,0.813974844,0.538508628,1.250759538,0.508057234,DB0907210064355_,0.677161171,-0.205825817,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium oxybate,DB09072
,53025,DB00958,10010774,136,4458,43,2542,0.000656985,1.803321214,1.266401663,2.613145269,0.003886757,DB0095810010774_,5.550180242,0.589630084,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,carboplatin,DB00958
,53026,DB01229,10010774,148,5593,43,2666,0.003675991,1.640534704,1.157088157,2.368411527,0.015943143,DB0122910010774_,4.138726444,0.495022228,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,paclitaxel,DB01229
,53027,DB00958,10012174,192,4402,73,2512,0.003297257,1.500806452,1.135063021,2.002045617,0.014605395,DB0095810012174_,4.226364269,0.406002598,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,carboplatin,DB00958
,53030,DB00958,10021015,118,4476,18,2567,3.5737886731619e-09,3.759091288,2.271626465,6.578205619,8.87454277506477e-08,DB0095810021015_,16.23749393,1.32417725,female,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,carboplatin,DB00958
,53031,DB01229,10021015,107,5634,10,2699,1.58846703003116e-09,5.125703433,2.67550293,11.01043102,4.24102142045395e-08,DB0122910021015_,16.9758766,1.634267771,female,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,paclitaxel,DB01229
,53040,DB06404,10047700,45,3024,12,888,0.874046953,1.10116386,0.569837228,2.297254821,0.945309283,DB0640410047700_,0.056243122,0.096367675,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,human c1-esterase inhibitor,DB06404
,53042,DB00186,10007617,158,16743,101,9907,0.561209125,0.925648969,0.715641373,1.201830722,0.713678698,DB0018610007617_,0.337322421,-0.0772602,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,lorazepam,DB00186
,53043,DB00193,10007617,196,19124,82,8620,0.602681751,1.077380544,0.827347274,1.413634005,0.746535806,DB0019310007617_,0.292311697,0.074532673,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,tramadol,DB00193
,53048,DB00437,10040047,162,6759,295,11251,0.378708629,0.914109346,0.748157126,1.113741099,0.548689138,DB0043710040047_,0.600223232,-0.08980508,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,allopurinol,DB00437
,53049,DB01076,10040047,252,25495,337,25246,0.00035718,0.740478425,0.625838717,0.875183409,0.002332008,DB0107610040047_,6.061025756,-0.300458781,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,53050,DB01377,10040047,88,3708,83,2587,0.058623951,0.739755988,0.539401764,1.015263377,0.140930177,DB0137710040047_,1.959490709,-0.301434893,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,magnesium oxide,DB01377
,53053,DB00051,10022437,204,25527,97,11323,0.572844187,0.932871344,0.728245356,1.201850204,0.722835608,DB0005110022437_,0.324573457,-0.069487983,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,adalimumab,DB00051
,53055,DB00181,10038669,28,9828,38,5833,0.0008503,0.4373414,0.258216449,0.732512747,0.00481547,DB0018110038669_,5.335921595,-0.827041153,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,baclofen,DB00181
,53056,DB06228,10061880,21,15891,32,16044,0.168921668,0.662580238,0.362947898,1.185579071,0.30939844,DB0622810061880_,1.173125384,-0.411613614,NA,10061880,Occult blood positive,10022891,Investigations,Inv,rivaroxaban,DB06228
,53064,DB00635,10022061,453,32600,68,23726,8.21180559497339e-47,4.848245761,3.748206819,6.355491636,4.2742041596807e-44,DB0063510022061_,99.86114617,1.578616941,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,53065,DB00635,10022112,81,32972,7,23787,1.86245173223530e-12,8.349233582,3.871069267,21.42088381,8.00564902400736e-11,DB0063510022112_,23.2482886,2.122169748,female,10022112,Injection site warmth,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,53066,DB00338,10013946,330,33344,164,22108,0.002660675,1.334134036,1.102121864,1.620124502,0.012258694,DB0033810013946_,4.401519846,0.288282419,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,53067,DB06228,10013946,93,15819,37,16039,5.83054846941691e-07,2.548510057,1.722519375,3.840937396,8.87411502713512e-06,DB0622810013946_,11.63237194,0.935508897,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,53068,DB08931,10013946,363,6214,102,2344,0.010062549,1.342347554,1.068927026,1.697816997,0.035740029,DB0893110013946_,3.331483945,0.294419987,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,53069,DB06228,10017885,72,15840,26,16050,2.19195070820314e-06,2.805981659,1.768460395,4.581081054,2.87430403417908e-05,DB0622810017885_,10.4571149,1.031753445,female,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,53070,DB08931,10017885,227,6350,47,2399,0.000104357,1.824565407,1.322544338,2.563404318,0.00082758,DB0893110017885_,7.097004193,0.601341825,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,53071,DB08931,10017955,119,6458,36,2410,0.315950382,1.233529213,0.840534092,1.849942233,0.48362193,DB0893110017955_,0.726451814,0.20987934,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,53072,DB08931,10048959,472,6105,160,2286,0.307507255,1.104604774,0.915192662,1.338521694,0.474650784,DB0893110048959_,0.745175936,0.0994876,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,53075,DB00087,10008531,33,1336,29,718,0.059576331,0.611677576,0.356875421,1.053585778,0.142665136,DB0008710008531_,1.947255104,-0.491549972,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,alemtuzumab,DB00087
,53084,DB00661,10003988,51,3477,13,1582,0.076289242,1.784781943,0.953378057,3.58818058,0.171951694,DB0066110003988_,1.760541691,0.579296247,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,verapamil,DB00661
,53086,DB01377,10003988,85,3711,33,2637,0.003279368,1.830140289,1.206871859,2.834226504,0.014543307,DB0137710003988_,4.230624412,0.604392625,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium oxide,DB01377
,53101,DB00437,10022437,92,6829,121,11425,0.087605974,1.272004286,0.957575749,1.685025492,0.191176672,DB0043710022437_,1.654557292,0.240593835,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,allopurinol,DB00437
,53103,DB00661,10022437,42,3486,18,1577,1,1.055544051,0.592381813,1.954641012,1,DB0066110022437_,0,0.054056322,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,verapamil,DB00661
,53104,DB01285,10022437,51,1225,30,579,0.395193471,0.803627529,0.496191308,1.321709349,0.564978732,DB0128510022437_,0.570967192,-0.21861939,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,corticotropin,DB01285
,53105,DB01377,10022437,60,3736,31,2639,0.164975537,1.367103524,0.869315926,2.188947237,0.304109064,DB0137710022437_,1.190368878,0.312694286,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,magnesium oxide,DB01377
,53108,DB00169,10041591,72,38619,10,18165,4.46192960818523e-05,3.386398065,1.738914829,7.361725547,0.000401032,DB0016910041591_,7.821469237,1.219766839,female,10041591,Spinal osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,53110,DB00338,10041591,43,33631,16,22256,0.046735167,1.778486992,0.981292371,3.383103296,0.118956781,DB0033810041591_,2.128995033,0.575762999,NA,10041591,Spinal osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,53121,DB00169,10050296,94,38597,22,18153,0.002609491,2.009533763,1.252329779,3.359407702,0.012066226,DB0016910050296_,4.417344981,0.697902736,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,53122,DB00193,10050296,43,19277,17,8685,0.780118254,1.139582432,0.636150105,2.13258899,0.880309353,DB0019310050296_,0.127481896,0.130661907,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,53123,DB00338,10050296,52,33622,35,22237,1,0.982619893,0.627800867,1.554684216,1,DB0033810050296_,0,-0.017532914,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,53126,DB00635,10050296,52,33001,23,23771,0.060251621,1.628513297,0.978881038,2.788769156,0.143920988,DB0063510050296_,1.938490825,0.487667511,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,53128,DB00695,10050296,38,28011,19,20509,0.182280786,1.464340549,0.823222922,2.6899385,0.326735575,DB0069510050296_,1.118604074,0.381405004,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,53129,DB00722,10050296,50,25353,25,26007,0.003575846,2.051551379,1.244974848,3.461935099,0.015588543,DB0072210050296_,4.16121906,0.718596277,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,53133,DB00480,10062352,89,67339,56,67606,0.006014938,1.595572266,1.12932745,2.271023119,0.023710656,DB0048010062352_,3.741830693,0.467232459,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,53134,DB00563,10003658,113,46533,47,15301,0.198634745,0.790571048,0.557571218,1.136501881,0.3474355,DB0056310003658_,1.057176244,-0.23499975,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,methotrexate,DB00563
,53137,DB00563,10033433,62,46584,15,15333,0.354624095,1.360451346,0.764571525,2.575911517,0.524463756,DB0056310033433_,0.645378956,0.307816517,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,53139,DB06643,10029148,70,52351,11,7504,0.737151104,0.912137225,0.479565995,1.911515679,0.848411278,DB0664310029148_,0.164389763,-0.091964835,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,denosumab,DB06643
,53141,DB06643,10031282,117,52304,10,7505,0.138437696,1.67879679,0.880606791,3.594349702,0.26758106,DB0664310031282_,1.31833273,0.51807734,NA,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,53154,DB00005,10013946,272,127810,74,42345,0.135650877,1.217788749,0.938390467,1.597241898,0.263648574,DB0000510013946_,1.333138224,0.197036713,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,53156,DB00169,10002198,81,38610,19,18156,0.005018663,2.004689347,1.204561871,3.50099329,0.020526814,DB0016910002198_,3.886023263,0.695489109,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,cholecalciferol,DB00169
,53158,DB00207,10002198,36,9044,16,5439,0.389495126,1.353107541,0.731149038,2.614225999,0.559382874,DB0020710002198_,0.580921114,0.30240383,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,azithromycin,DB00207
,53169,DB00196,10008479,67,5016,34,3251,0.261020578,1.277145572,0.831055464,1.995359487,0.422522841,DB0019610008479_,0.861511771,0.244627566,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,53171,DB00482,10008479,77,8182,42,3029,0.048666542,0.678730564,0.459002881,1.015913603,0.122563961,DB0048210008479_,2.099122257,-0.387531044,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,53172,DB00668,10008479,141,9950,51,4252,0.341168492,1.181436641,0.85011131,1.664573636,0.510320888,DB0066810008479_,0.672715559,0.16673119,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,53174,DB00983,10008479,74,3427,20,1720,0.014575604,1.856822633,1.116231471,3.224931933,0.048176014,DB0098310008479_,3.03289402,0.618866765,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,formoterol,DB00983
,53175,DB01175,10008479,119,10605,42,4850,0.171554509,1.295708192,0.902783339,1.892031492,0.312853247,DB0117510008479_,1.162021058,0.259057412,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,53177,DB01224,10008479,72,8036,31,5886,0.01229829,1.701116567,1.100422392,2.685911089,0.041973714,DB0122410008479_,3.170711706,0.531284839,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,53187,DB00451,10010071,60,47211,15,15404,0.42137818,1.305102381,0.731717558,2.475503757,0.590435306,DB0045110010071_,0.526895207,0.266281491,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,53197,DB00196,10015150,33,5050,21,3264,1,1.01567053,0.569271979,1.850804021,1,DB0019610015150_,0,0.015549015,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,fluconazole,DB00196
,53198,DB00341,10015150,148,11257,46,5022,0.034389173,1.43534909,1.022793463,2.047951751,0.094189083,DB0034110015150_,2.362450993,0.361408088,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,cetirizine,DB00341
,53200,DB00482,10015150,57,8202,11,3060,0.040627178,1.933178519,1.001697844,4.093787192,0.106906134,DB0048210015150_,2.235804081,0.659165549,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,celecoxib,DB00482
,53201,DB00668,10015150,84,10007,27,4276,0.212910928,1.329312669,0.851229723,2.137309636,0.364916781,DB0066810015150_,1.008085949,0.284662018,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,epinephrine,DB00668
,53204,DB01175,10015150,73,10651,18,4874,0.017007658,1.855796599,1.09489506,3.307685672,0.054408297,DB0117510015150_,2.91123861,0.618314037,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,escitalopram,DB01175
,53211,DB00482,10019211,345,7914,90,2981,0.002029086,1.443931965,1.137121651,1.849014689,0.009836691,DB0048210019211_,4.62163592,0.367369924,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,53212,DB00776,10019211,99,1806,35,1304,0.000222456,2.041901676,1.365945075,3.11530066,0.001575868,DB0077610019211_,6.452948797,0.713881568,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,oxcarbazepine,DB00776
,53213,DB00983,10019211,146,3355,30,1710,1.27426603965326e-06,2.480115161,1.657147952,3.823790937,1.77640322738191e-05,DB0098310019211_,10.9383348,0.908304995,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,formoterol,DB00983
,53215,DB01224,10019211,238,7870,84,5833,1.49778197040172e-09,2.09985386,1.626834993,2.732618697,4.00908341059156e-08,DB0122410019211_,17.0321181,0.741867752,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,53218,DB06404,10019211,62,3007,20,880,0.690343085,0.907226651,0.537023961,1.595016696,0.813196557,DB0640410019211_,0.206782431,-0.097362969,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,human c1-esterase inhibitor,DB06404
,53222,DB00341,10019860,62,11343,8,5060,0.000222845,3.456705923,1.648262927,8.366917062,0.001578073,DB0034110019860_,6.451550722,1.24031609,female,10019860,Hereditary angioedema,10010331,"Congenital, familial and genetic disorders",Cong,cetirizine,DB00341
,53231,DB00196,10028411,46,5037,14,3271,0.011355882,2.133544239,1.150262004,4.209380499,0.039394135,DB0019610028411_,3.23413833,0.757784559,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fluconazole,DB00196
,53232,DB00338,10028411,390,33284,193,22079,0.000894754,1.340444244,1.124206516,1.602612088,0.005025881,DB0033810028411_,5.293154482,0.293001084,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,53233,DB00482,10028411,102,8157,18,3053,0.00189017,2.120821271,1.274201212,3.727390913,0.009289168,DB0048210028411_,4.678906336,0.751803406,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,53234,DB00668,10028411,63,10028,13,4290,0.016275251,2.073106255,1.127870303,4.111225251,0.052537752,DB0066810028411_,2.946223286,0.729048089,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,epinephrine,DB00668
,53238,DB01224,10028411,51,8057,25,5892,0.104230834,1.491788082,0.906191741,2.515584012,0.217385343,DB0122410028411_,1.526083725,0.399975456,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,quetiapine,DB01224
,53245,DB00338,10038669,45,33629,28,22244,0.904872016,1.063056563,0.648684933,1.770187309,0.957667115,DB0033810038669_,0.043255041,0.061148309,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,53248,DB00451,10038669,50,47221,30,15389,0.012811385,0.543177273,0.33859081,0.885089072,0.043389673,DB0045110038669_,3.137533826,-0.610319542,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,53253,DB01175,10038669,41,10683,14,4878,0.385342615,1.337254083,0.713285951,2.658553997,0.55548594,DB0117510038669_,0.58791198,0.29061832,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,53255,DB01224,10038669,157,7951,87,5830,0.042444346,1.323178344,1.009497262,1.743798039,0.110580794,DB0122410038669_,2.20200886,0.280036679,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,quetiapine,DB01224
,53259,DB00207,10038695,90,8990,111,5344,3.25046501169257e-07,0.481993485,0.360099441,0.643666854,5.24967575006693e-06,DB0020710038695_,12.15734425,-0.729824682,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,53260,DB00341,10038695,72,11333,36,5032,0.601035614,0.888039278,0.586419119,1.366243515,0.745334479,DB0034110038695_,0.293922197,-0.118739305,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,53266,DB01224,10038695,75,8033,42,5875,0.188177643,1.305971505,0.882100169,1.956587284,0.334292624,DB0122410038695_,1.095738548,0.266947212,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,quetiapine,DB01224
,53271,DB00207,10042674,55,9025,17,5438,0.014428592,1.94933786,1.113181585,3.586522071,0.047756159,DB0020710042674_,3.041647239,0.667489756,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,53272,DB00341,10042674,120,11285,36,5032,0.036517242,1.486319624,1.014885716,2.22497493,0.098611359,DB0034110042674_,2.316568825,0.396303013,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,53274,DB00668,10042674,79,10012,20,4283,0.036068264,1.689702443,1.022631138,2.918478014,0.097660454,DB0066810042674_,2.326258569,0.524552444,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,53281,DB00196,10047700,167,4916,78,3207,0.016709423,1.396664206,1.05704467,1.85866099,0.053659849,DB0019610047700_,2.925090254,0.334086684,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,fluconazole,DB00196
,53283,DB00983,10047700,78,3423,23,1717,0.02492162,1.700944885,1.052426115,2.849052942,0.073310368,DB0098310047700_,2.613053232,0.531183911,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,formoterol,DB00983
,53287,DB00196,10053762,169,4914,122,3163,0.359538108,0.891657273,0.6991056,1.139927231,0.529229947,DB0019610053762_,0.636332259,-0.114673444,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,fluconazole,DB00196
,53288,DB00341,10053762,380,11025,139,4929,0.047507712,1.222181123,1.000709086,1.499684078,0.120418534,DB0034110053762_,2.116781818,0.200637069,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,53290,DB00668,10053762,106,9985,71,4232,0.003722501,0.632790699,0.46305875,0.86910408,0.016091759,DB0066810053762_,4.129448002,-0.45761556,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,epinephrine,DB00668
,53291,DB00776,10053762,80,1825,59,1280,0.792037842,0.95104771,0.66549139,1.365555607,0.887420002,DB0077610053762_,0.1194369,-0.05019105,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,oxcarbazepine,DB00776
,53294,DB00650,10035664,33,2098,50,1964,0.03496554,0.617921858,0.383873089,0.982916622,0.095358914,DB0065010035664_,2.350107466,-0.481393273,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,leucovorin,DB00650
,53302,DB00003,10013968,99,2899,104,2489,0.173132241,0.817326849,0.610991417,1.092769059,0.314998335,DB0000310013968_,1.155187925,-0.201716204,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dornase alfa,DB00003
,53304,DB00479,10013968,53,562,23,376,0.112070065,1.54106928,0.910195307,2.682081431,0.229188645,DB0047910013968_,1.473209838,0.432476513,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amikacin,DB00479
,53306,DB01211,10013968,46,1606,22,765,1,0.995982611,0.582217601,1.751706759,1,DB0121110013968_,0,-0.004025481,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clarithromycin,DB01211
,53333,DB00193,10033318,74,19246,25,8677,0.232319863,1.334441229,0.837288456,2.194009956,0.388752713,DB0019310033318_,0.944811838,0.288512649,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,tramadol,DB00193
,53336,DB00904,10033318,133,22936,42,14414,6.33000791774079e-05,1.990035871,1.396175299,2.888623056,0.000538984,DB0090410033318_,7.525825289,0.688152664,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,ondansetron,DB00904
,53337,DB01050,10033318,58,18050,15,9356,0.013331209,2.004194569,1.120373599,3.809972661,0.044766633,DB0105010033318_,3.106292209,0.695242269,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,ibuprofen,DB01050
,53339,DB01373,10033318,71,22649,20,7361,0.627100841,1.153754252,0.693793531,2.002494439,0.7665781,DB0137310033318_,0.265818694,0.143021192,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,calcium,DB01373
,53340,DB09153,10033318,50,7749,27,5672,0.247078022,1.355460666,0.831373731,2.254782708,0.406220223,DB0915310033318_,0.900859845,0.304141371,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,sodium chloride,DB09153
,53341,DB08893,10013709,154,1931,88,970,0.357977449,0.879120338,0.664220738,1.169200391,0.527701041,DB0889310013709_,0.639225366,-0.128833487,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,mirabegron,DB08893
,53342,DB00909,10013709,82,738,53,428,0.572857102,0.897352652,0.614023877,1.320149904,0.722835608,DB0090910013709_,0.324573457,-0.108306348,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,zonisamide,DB00909
,53343,DB00451,10000125,52,47219,13,15406,0.471636486,1.305050716,0.700501719,2.613384652,0.637802389,DB0045110000125_,0.449726778,0.266241903,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,53346,DB00451,10029412,80,47191,23,15396,0.648202352,1.134774125,0.705922471,1.891840814,0.783212229,DB0045110029412_,0.244351574,0.126433623,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,53352,DB00441,10046571,47,2227,32,1862,0.424989261,1.227964494,0.76363621,1.997381011,0.593735827,DB0044110046571_,0.521320794,0.205357916,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,gemcitabine,DB00441
,53353,DB00515,10047895,40,1830,60,2091,0.222972757,0.761800903,0.494883513,1.161771618,0.377193907,DB0051510047895_,0.974995881,-0.272070039,NA,10047895,Weight decreased,10022891,Investigations,Inv,cisplatin,DB00515
,53356,DB00515,10063743,27,1843,33,2118,0.896452493,0.940262649,0.541629331,1.619378603,0.956301489,DB0051510063743_,0.044682051,-0.061596029,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,cisplatin,DB00515
,53362,DB09072,10028411,56,6415,18,2517,0.518017235,1.220642849,0.705252596,2.210930304,0.677438866,DB0907210028411_,0.389435965,0.199377645,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium oxybate,DB09072
,53366,DB00904,10008190,172,22897,109,14347,0.950961678,0.988742955,0.772604374,1.26993737,0.989177772,DB0090410008190_,0.010881214,-0.011320885,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,53367,DB05676,10061623,899,46230,500,24829,0.533534287,0.965691521,0.863705661,1.080618483,0.690239879,DB0567610061623_,0.370716092,-0.034910833,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,53369,DB01212,10037844,72,1947,67,1874,0.863226216,1.03433462,0.726525249,1.474202053,0.936805644,DB0121210037844_,0.065279442,0.033758341,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ceftriaxone,DB01212
,53373,DB00480,10003399,39,67389,45,67617,0.585577232,0.869600432,0.551439165,1.365890027,0.733042313,DB0048010003399_,0.310551854,-0.139721446,NA,10003399,Arthropod bite,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,53374,DB00480,10008531,212,67216,204,67458,0.694515007,1.042970029,0.856203193,1.270627804,0.816125866,DB0048010008531_,0.203186689,0.04207244,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,53375,DB00480,10013946,247,67181,144,67518,1.55914665130884e-07,1.723864284,1.39760506,2.132701493,2.71855188919753e-06,DB0048010013946_,12.81541121,0.544568447,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,53376,DB00480,10029410,153,67275,119,67543,0.038958579,1.290830125,1.008954145,1.654755093,0.103552054,DB0048010029410_,2.267680859,0.255285519,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,53388,DB00331,10047943,65,24881,39,20713,0.11482118,1.387458822,0.918416241,2.120788162,0.233380352,DB0033110047943_,1.455085742,0.327473888,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,metformin,DB00331
,53390,DB13961,10047943,35,9422,19,6395,0.488756443,1.250269708,0.695152276,2.315977077,0.652262546,DB1396110047943_,0.42730812,0.223359294,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,fish oil,DB13961
,53391,DB00230,10028735,89,19585,15,8636,0.00024241,2.61622889,1.502946382,4.87256474,0.001690043,DB0023010028735_,6.383001594,0.961733926,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,53395,DB00005,10027374,38,128044,19,42400,0.166373551,0.662274407,0.372417638,1.216336434,0.305952271,DB0000510027374_,1.184326167,-0.412075296,NA,10027374,Mental impairment,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,53396,DB01611,10035528,49,11864,9,2352,1,1.079364387,0.523765826,2.502653295,1,DB0161110035528_,0,0.076372337,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,hydroxychloroquine,DB01611
,53415,DB00264,10015946,47,29560,23,24869,0.040484135,1.719168959,1.022874591,2.967365257,0.106609955,DB0026410015946_,2.238578382,0.541841011,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,metoprolol,DB00264
,53417,DB00641,10015946,51,14073,25,12450,0.015387124,1.80468768,1.097005495,3.041866314,0.050295412,DB0064110015946_,2.989841419,0.590387546,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,simvastatin,DB00641
,53420,DB00213,10015958,47,18848,11,13410,0.00042212,3.039833726,1.553245656,6.501600404,0.002677793,DB0021310015958_,5.922762398,1.111802818,female,10015958,Eye pain,10015919,Eye disorders,Eye,pantoprazole,DB00213
,53422,DB00641,10015958,43,14081,25,12450,0.113220711,1.520744541,0.907495233,2.599837257,0.230912972,DB0064110015958_,1.465714385,0.419200045,NA,10015958,Eye pain,10015919,Eye disorders,Eye,simvastatin,DB00641
,53428,DB00641,10030041,38,14086,26,12449,0.380228578,1.291671909,0.763570719,2.216973822,0.550337744,DB0064110030041_,0.59722311,0.255937433,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,simvastatin,DB00641
,53431,DB01098,10048959,176,7973,96,7113,0.000105983,1.635525363,1.265474828,2.124342081,0.000838339,DB0109810048959_,7.084088199,0.491964076,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,53445,DB00181,10006093,53,9803,47,5824,0.048831352,0.66998979,0.443121401,1.015643119,0.122805352,DB0018110006093_,2.09715468,-0.400492806,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,baclofen,DB00181
,53448,DB00996,10006093,89,38864,105,22320,6.51094058262958e-07,0.486792258,0.362662105,0.65221106,9.78782231709571e-06,DB0099610006093_,11.53437157,-0.719917823,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,gabapentin,DB00996
,53449,DB01068,10006093,107,13656,55,6785,0.867037994,0.966629583,0.690935508,1.365455077,0.940127206,DB0106810006093_,0.061740087,-0.033939915,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,clonazepam,DB01068
,53454,DB00996,10012373,74,38879,107,22318,8.33896260464335e-10,0.397001916,0.290980549,0.539204992,2.35687776411882e-08,DB0099610012373_,17.56334298,-0.923814171,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,53460,DB00313,10033295,36,1203,52,1465,0.448477248,0.843136787,0.531599957,1.324435545,0.616184437,DB0031310033295_,0.484208949,-0.170626072,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,valproic acid,DB00313
,53461,DB00863,10033295,43,10630,22,5818,0.896758492,1.069760984,0.625229415,1.879746303,0.956316819,DB0086310033295_,0.04466602,0.067435244,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,53463,DB06724,10033295,32,7897,24,3895,0.119811628,0.657642828,0.37478176,1.168577829,0.241118492,DB0672410033295_,1.422466796,-0.41909331,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium carbonate,DB06724
,53464,DB00863,10041349,128,10545,59,5781,0.282624832,1.189323648,0.865554851,1.650637112,0.446737248,DB0086310041349_,0.805784669,0.173384782,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,53465,DB01068,10041349,328,13435,189,6651,0.10774627,0.85915004,0.714377023,1.035622865,0.222711493,DB0106810041349_,1.5018781,-0.151811704,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,53466,DB06724,10041349,85,7844,26,3893,0.032877302,1.622468058,1.033122203,2.628292113,0.091023793,DB0672410041349_,2.396634345,0.483948483,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,53473,DB06228,10002855,99,15813,55,16021,0.000348298,1.823631275,1.297601559,2.585923192,0.002285041,DB0622810002855_,6.08137142,0.600829719,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,rivaroxaban,DB06228
,53474,DB08932,10039163,365,19078,133,6464,0.466943751,0.929839295,0.758788845,1.145102743,0.633505408,DB0893210039163_,0.456486743,-0.072743508,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,macitentan,DB08932
,53475,DB00203,10000087,353,13525,118,8820,8.83712380259587e-11,1.950791416,1.57662091,2.428118551,2.89450217010881e-09,DB0020310000087_,19.6604527,0.668235145,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,53482,DB00415,10013700,276,510,59,483,5.00491406387672e-25,4.42566431,3.23443386,6.129952903,7.62632847356519e-23,DB0041510013700_,50.92785061,1.487420394,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ampicillin,DB00415
,53484,DB00497,10040882,36,19231,23,16352,0.29846929,1.330882014,0.767033879,2.353567372,0.46445048,DB0049710040882_,0.766900336,0.285841891,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,53489,DB01273,10000059,41,1999,11,1264,0.009392466,2.356274563,1.184023254,5.103165931,0.033858737,DB0127310000059_,3.38555821,0.857081797,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,varenicline,DB01273
,53492,DB00051,10001949,67,25664,32,11388,0.743942215,0.929072728,0.600727244,1.464219338,0.853685547,DB0005110001949_,0.158192365,-0.073568257,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,53493,DB00193,10001949,90,19230,28,8674,0.090347415,1.449862897,0.938692656,2.303915404,0.19578563,DB0019310001949_,1.630734945,0.371468998,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,53494,DB00273,10001949,64,8417,13,2180,0.481473743,1.275044139,0.693745187,2.528268999,0.646092395,DB0027310001949_,0.436812759,0.242980797,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,53495,DB01175,10001949,62,10662,27,4865,0.909016159,1.047781385,0.655901389,1.71522834,0.959134927,DB0117510001949_,0.041723518,0.046674962,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,53501,DB01175,10014625,24,10700,30,4862,0.00030808,0.363539794,0.203161513,0.644013984,0.002062365,DB0117510014625_,6.183902026,-1.011866515,male,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,53506,DB00051,10070863,48,25683,27,11393,0.318644511,0.788659245,0.482037435,1.315195323,0.486668854,DB0005110070863_,0.720171359,-0.237420933,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,53507,DB00193,10070863,681,18639,357,8345,0.018372397,0.85406583,0.748278776,0.976047426,0.057791792,DB0019310070863_,2.850908524,-0.157747004,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,53508,DB00273,10070863,372,8109,107,2086,0.325320172,0.894340035,0.715339562,1.125669599,0.493723302,DB0027310070863_,0.705780037,-0.111669224,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,topiramate,DB00273
,53510,DB01015,10016288,148,9739,242,9139,8.99000284808474e-08,0.573913988,0.463600601,0.708561995,1.64155765795003e-06,DB0101510016288_,13.31986498,-0.555275741,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,sulfamethoxazole,DB01015
,53511,DB01015,10024384,58,9829,81,9300,0.026546019,0.677529396,0.474490827,0.96219868,0.076956226,DB0101510024384_,2.564518516,-0.389302338,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,sulfamethoxazole,DB01015
,53512,DB01015,10029354,187,9700,174,9207,0.873386835,1.020092319,0.823660203,1.263870269,0.944886934,DB0101510029354_,0.056690005,0.019893132,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,sulfamethoxazole,DB01015
,53513,DB00559,10018836,47,9612,10,3296,0.221925526,1.611535389,0.802526087,3.581277889,0.375930427,DB0055910018836_,0.978351187,0.477187382,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,53515,DB06228,10024855,86,15826,65,16011,0.086427454,1.338526214,0.95788255,1.878189569,0.18907579,DB0622810024855_,1.665607337,0.291569168,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,53523,DB01222,10011906,291,8983,286,5119,1.88254248935182e-10,0.579868488,0.489009775,0.687577387,5.88378470066738e-09,DB0122210011906_,18.95106563,-0.544953946,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,53524,DB00471,10035664,649,13540,284,5181,0.066682997,0.874440388,0.756557566,1.012589044,0.15537298,DB0047110035664_,1.861926733,-0.134171154,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,montelukast,DB00471
,53525,DB00584,10035664,66,2015,68,1806,0.430012821,0.869948606,0.606668269,1.246890977,0.598495513,DB0058410035664_,0.513336252,-0.139321143,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,enalapril,DB00584
,53526,DB00169,10040753,718,37973,180,17995,1.0650955891025e-15,1.890272705,1.601471168,2.240431581,7.09658746756888e-14,DB0016910040753_,30.27657727,0.636721107,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,53528,DB00455,10040753,242,9159,64,5054,4.17512900608419e-08,2.086424511,1.57431764,2.799171394,8.18979596454649e-07,DB0045510040753_,14.01520667,0.735451841,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,loratadine,DB00455
,53529,DB00471,10040753,576,13613,123,5342,2.11914769217161e-10,1.837619882,1.505951609,2.25690905,6.56473742943202e-09,DB0047110040753_,18.84155333,0.608471192,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,montelukast,DB00471
,53532,DB01202,10040753,33,6681,22,5696,0.417131941,1.278823908,0.722608017,2.305227591,0.5862642,DB0120210040753_,0.533984737,0.245940833,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,levetiracetam,DB01202
,53533,DB01222,10040753,318,8956,89,5316,5.21613648366829e-11,2.120738639,1.667160187,2.720615275,1.77944383482441e-09,DB0122210040753_,20.14696497,0.751764442,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,budesonide,DB01222
,53537,DB00065,10012378,70,9394,25,4932,0.104461746,1.470007829,0.917893347,2.426185819,0.217685574,DB0006510012378_,1.524703576,0.385267727,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,infliximab,DB00065
,53538,DB00065,10015150,110,9354,43,4914,0.104520428,1.343866026,0.934858066,1.962458435,0.217790594,DB0006510015150_,1.524221258,0.295550554,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,infliximab,DB00065
,53540,DB00065,10047899,71,9393,31,4926,0.464065375,1.201079673,0.776059885,1.898312268,0.631298953,DB0006510047899_,0.459975752,0.18322088,NA,10047899,Weight increased,10022891,Investigations,Inv,infliximab,DB00065
,53545,DB00381,10018484,35,29325,48,22839,0.010803315,0.567908189,0.356396538,0.896803172,0.037872116,DB0038110018484_,3.273540163,-0.565795513,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,amlodipine,DB00381
,53546,DB00722,10018484,55,25348,63,25969,0.580766995,0.894406152,0.61114791,1.305568351,0.729218519,DB0072210018484_,0.31578184,-0.111595298,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,lisinopril,DB00722
,53547,DB00999,10018484,34,21396,37,12202,0.008959817,0.524048261,0.318916226,0.858786629,0.032596373,DB0099910018484_,3.423554262,-0.646171498,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,53549,DB00381,10050296,42,29318,21,22866,0.099643373,1.559845291,0.90289892,2.773484825,0.210219606,DB0038110050296_,1.559602553,0.444586644,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,53556,DB00068,10033425,61,2173,18,647,1,1.009022917,0.583355645,1.827887808,1,DB0006810033425_,0,0.008982454,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1b,DB00068
,53558,DB00402,10013709,88,1264,53,643,0.357658102,0.84471929,0.585663437,1.227865519,0.527362407,DB0040210013709_,0.639867288,-0.168750908,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,eszopiclone,DB00402
,53568,DB01373,10003119,46,22674,12,7369,0.646476024,1.24580913,0.649000401,2.585161297,0.781899104,DB0137310003119_,0.24602957,0.219785222,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,calcium,DB01373
,53572,DB05676,10003549,274,46855,151,25178,0.798872361,0.975060195,0.796033282,1.198118026,0.891356522,DB0567610003549_,0.115010795,-0.025256072,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,53573,DB00051,10017367,51,25680,50,11370,8.45439113600338e-05,0.451615189,0.299481535,0.68135804,0.000691532,DB0005110017367_,7.276601749,-0.794924813,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,53581,DB00874,10019211,168,3167,57,1919,0.00013316,1.785734695,1.307302839,2.469412589,0.001017476,DB0087410019211_,6.890430455,0.579829924,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,guaifenesin,DB00874
,53593,DB00874,10028813,211,3124,67,1909,2.1148098339519e-06,1.924210135,1.446044688,2.587783851,2.78565655151219e-05,DB0087410028813_,10.48844187,0.654515564,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,guaifenesin,DB00874
,53595,DB00177,10010774,83,4717,44,2806,0.579411438,1.122144481,0.766985624,1.661331955,0.728091307,DB0017710010774_,0.317328816,0.11524157,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,valsartan,DB00177
,53596,DB00268,10010774,54,2921,37,1508,0.219040281,0.753538013,0.484405319,1.183416684,0.372362811,DB0026810010774_,0.987886602,-0.282975814,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ropinirole,DB00268
,53597,DB00423,10010774,38,2429,16,1024,1,1.001234766,0.542234164,1.932597059,1,DB0042310010774_,0,0.001234004,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,methocarbamol,DB00423
,53598,DB01098,10010774,168,7981,111,7098,0.018081584,1.346033046,1.050462476,1.730262208,0.057055756,DB0109810010774_,2.863726316,0.297161782,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,53599,DB09053,10010774,48,2237,50,4002,0.010539961,1.717376249,1.127136757,2.613855352,0.037122185,DB0905310010774_,3.29354052,0.540797689,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ibrutinib,DB09053
,53600,DB00423,10016256,141,2326,59,981,1,1.007918566,0.731420715,1.403205248,1,DB0042310016256_,0,0.007887379,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,methocarbamol,DB00423
,53601,DB00177,10028813,283,4517,102,2748,5.1597367192409e-06,1.687813954,1.334233437,2.148878104,6.09059007076802e-05,DB0017710028813_,9.706180496,0.523434173,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,valsartan,DB00177
,53602,DB00423,10028813,161,2306,53,987,0.122161447,1.300149644,0.938440084,1.825157907,0.244527558,DB0042310028813_,1.408427263,0.262479369,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,methocarbamol,DB00423
,53603,DB09053,10028813,91,2194,110,3942,0.007066428,1.486211745,1.107597578,1.990441431,0.0269796,DB0905310028813_,3.612674236,0.396230429,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ibrutinib,DB09053
,53604,DB00177,10035664,141,4659,96,2754,0.3061671,0.868219425,0.662163641,1.142393683,0.473110067,DB0017710035664_,0.748427219,-0.141310803,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,valsartan,DB00177
,53605,DB00423,10035664,90,2377,39,1001,0.92178637,0.971820318,0.655147194,1.46471712,0.965458827,DB0042310035664_,0.035151822,-0.02858435,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,methocarbamol,DB00423
,53606,DB00697,10035664,192,5904,60,1746,0.703409286,0.946343092,0.70098459,1.293137473,0.822103739,DB0069710035664_,0.195888689,-0.0551501,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,tizanidine,DB00697
,53607,DB01039,10035664,85,2888,102,2949,0.298505539,0.850958549,0.627461171,1.151642224,0.46447939,DB0103910035664_,0.766838093,-0.161391861,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,fenofibrate,DB01039
,53608,DB00177,10037660,73,4727,48,2802,0.571238726,0.901511192,0.615838334,1.330212006,0.721511252,DB0017710037660_,0.326407305,-0.103682822,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,53609,DB00423,10037660,36,2431,24,1016,0.086880996,0.626992906,0.36179207,1.104631366,0.189852257,DB0042310037660_,1.661509105,-0.466820052,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,methocarbamol,DB00423
,53610,DB00715,10037660,94,4749,35,2252,0.253517057,1.273494425,0.852355922,1.941603907,0.414044972,DB0071510037660_,0.881780682,0.241764638,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,53611,DB00956,10037660,82,5732,33,3434,0.064829928,1.488594121,0.98014776,2.30792329,0.152168116,DB0095610037660_,1.882769344,0.397832132,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,53612,DB01039,10037660,43,2930,53,2998,0.410712849,0.830176741,0.540146164,1.26959643,0.580096036,DB0103910037660_,0.54456161,-0.186116659,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,53613,DB00177,10046571,115,4685,25,2825,5.69824220260007e-07,2.773417169,1.782277455,4.474188566,8.70804048228737e-06,DB0017710046571_,11.65126377,1.020080195,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,valsartan,DB00177
,53614,DB00423,10046571,53,2414,8,1032,0.00419461,2.831540066,1.331305644,6.921300615,0.01775305,DB0042310046571_,4.031197965,1.040820757,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,methocarbamol,DB00423
,53615,DB00715,10046571,108,4735,30,2257,0.007564677,1.715870325,1.131922403,2.67306469,0.028484712,DB0071510046571_,3.558387761,0.53992043,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,paroxetine,DB00715
,53616,DB00956,10046571,111,5703,26,3441,4.29838098725253e-06,2.575680058,1.664365315,4.123128155,5.17084413043171e-05,DB0095610046571_,9.869889515,0.946113599,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,hydrocodone,DB00956
,53617,DB01039,10046571,75,2898,39,3012,0.00042751,1.998488642,1.33487178,3.03374788,0.002708851,DB0103910046571_,5.911230556,0.692391216,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,fenofibrate,DB01039
,53618,DB00005,10021425,182,127900,78,42341,0.061744342,0.772445975,0.589192728,1.020715438,0.146647694,DB0000510021425_,1.919722205,-0.258193208,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,etanercept,DB00005
,53619,DB00005,10056663,61,128021,9,42410,0.018338821,2.245138415,1.108339943,5.14360856,0.057697756,DB0000510056663_,2.852536998,0.808767174,NA,10056663,Gastric infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,53621,DB00727,10000891,48,3795,68,4105,0.161149668,0.763570502,0.514971128,1.124437952,0.299023615,DB0072710000891_,1.207232729,-0.269749819,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,nitroglycerin,DB00727
,53623,DB00295,10007515,222,14441,158,9444,0.428001697,0.918875264,0.744638142,1.136016202,0.596507015,DB0029510007515_,0.516664278,-0.084604897,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,morphine,DB00295
,53624,DB00727,10007515,53,3790,68,4105,0.409400965,0.844209852,0.576460306,1.230618235,0.578802946,DB0072710007515_,0.546793195,-0.169354176,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,nitroglycerin,DB00727
,53625,DB01109,10007515,61,4351,103,4167,0.000488581,0.56722891,0.405116992,0.788457515,0.003035143,DB0110910007515_,5.797496673,-0.566992336,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,heparin,DB01109
,53628,DB00758,10042316,24,8276,39,10035,0.310453285,0.746192611,0.428871023,1.273578749,0.477865171,DB0075810042316_,0.738426655,-0.29277152,NA,10042316,Subarachnoid haemorrhage,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,53635,DB00727,10048294,40,3803,30,4143,0.148877154,1.452459745,0.880277361,2.420171927,0.282431959,DB0072710048294_,1.264317612,0.373258495,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,nitroglycerin,DB00727
,53636,DB00758,10048294,47,8253,65,10009,0.506746654,0.876943455,0.588673819,1.297663739,0.667426758,DB0075810048294_,0.404325621,-0.131312764,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,clopidogrel,DB00758
,53643,DB06724,10033425,218,7711,46,3873,1.3207425918089e-08,2.380172451,1.72053193,3.354916572,2.88576218002469e-07,DB0672410033425_,15.0583066,0.867172943,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,53645,DB00264,10043414,45,29562,40,24852,0.827963697,0.94572858,0.603683656,1.486398722,0.909558014,DB0026410043414_,0.094796497,-0.055799664,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,53647,DB00695,10043414,51,27998,32,20496,0.507372352,1.166682418,0.735236585,1.876670518,0.668016543,DB0069510043414_,0.403442341,0.154164181,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,53664,DB08904,10010264,133,11477,47,3512,0.425617561,0.865956841,0.615163575,1.237590016,0.594345088,DB0890410010264_,0.520295172,-0.143920209,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,53676,DB00480,10025197,96,67332,51,67611,0.00018851,1.890132514,1.332011322,2.70982066,0.001371432,DB0048010025197_,6.591899503,0.63664694,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,lenalidomide,DB00480
,53680,DB00480,10026865,65,67363,54,67608,0.314337366,1.20807808,0.82895472,1.766809539,0.481939863,DB0048010026865_,0.729935939,0.189030733,NA,10026865,Mass,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,53701,DB00181,10010071,69,9787,68,5803,0.003332182,0.601696051,0.423440385,0.855165232,0.014722886,DB0018110010071_,4.218352107,-0.508002859,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,53704,DB00956,10013754,53,5761,25,3442,0.349718113,1.266609103,0.771733037,2.131225527,0.519297269,DB0095610013754_,0.655278787,0.236343332,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,53708,DB00181,10022523,34,9822,24,5847,0.586733566,0.843352371,0.485078773,1.488034269,0.733875946,DB0018110022523_,0.309415275,-0.170370411,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,53711,DB01233,10041349,38,3383,12,1714,0.176261025,1.604259445,0.818113016,3.380973236,0.31903464,DB0123310041349_,1.142455591,0.472662245,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,metoclopramide,DB01233
,53714,DB00181,10057668,70,9786,35,5836,0.419624233,1.192752468,0.782943698,1.84688368,0.588568398,DB0018110057668_,0.530062135,0.176263634,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,53718,DB00480,10042674,273,67155,252,67410,0.35847617,1.087423049,0.912654621,1.29619407,0.528169626,DB0048010042674_,0.638337786,0.083810722,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,53725,DB00999,10015916,59,21371,14,12225,0.002102222,2.41066868,1.329075524,4.677189208,0.010135163,DB0099910015916_,4.591744461,0.87990417,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,hydrochlorothiazide,DB00999
,53731,DB00227,10047895,48,2419,33,1770,0.821103727,1.064298546,0.666089565,1.71915839,0.904725148,DB0022710047895_,0.100124085,0.06231594,NA,10047895,Weight decreased,10022891,Investigations,Inv,lovastatin,DB00227
,53732,DB14500,10047895,214,7595,128,3945,0.224787741,0.868423418,0.691934201,1.093487691,0.379494895,DB1450010047895_,0.968914133,-0.141075874,NA,10047895,Weight decreased,10022891,Investigations,Inv,potassium,DB14500
,53736,DB01254,10060933,155,3312,155,2993,0.414876491,0.903697941,0.714537771,1.142934668,0.584093657,DB0125410060933_,0.537693938,-0.101260111,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,dasatinib,DB01254
,53739,DB00682,10021143,219,19240,131,16233,0.002074002,1.410462495,1.12955573,1.766879441,0.010022087,DB0068210021143_,4.602963906,0.343917661,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,53741,DB00682,10061224,57,19402,27,16337,0.015364131,1.777579464,1.105437444,2.924660364,0.050238999,DB0068210061224_,2.990963691,0.575252587,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,53755,DB00433,10009657,38,7618,17,6003,0.056436766,1.761335677,0.969227952,3.331429847,0.136875357,DB0043310009657_,1.988684571,0.566072429,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,53756,DB00512,10009657,73,4664,31,5067,6.62113090509539e-06,2.558079723,1.655631252,4.03771328,7.56680112349705e-05,DB0051210009657_,9.48915506,0.939256869,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,vancomycin,DB00512
,53764,DB00761,10009657,48,15259,33,8592,0.417234758,0.81903988,0.514539519,1.318159547,0.586377351,DB0076110009657_,0.533791752,-0.199622503,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,53765,DB00787,10009657,81,16919,44,17204,0.000843875,1.871873493,1.280361201,2.768879538,0.004785601,DB0078710009657_,5.34214356,0.626939797,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,acyclovir,DB00787
,53769,DB00987,10009657,24,2080,37,2891,0.794229252,0.901553472,0.514283101,1.553090857,0.888516684,DB0098710009657_,0.118201854,-0.103635924,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,cytarabine,DB00987
,53774,DB00421,10010305,114,8789,60,5192,0.527713128,1.122413924,0.812394479,1.564142012,0.685234831,DB0042110010305_,0.377993681,0.115481655,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,spironolactone,DB00421
,53775,DB00512,10010305,41,4696,83,5015,0.000761754,0.527567178,0.352947941,0.777738798,0.004389022,DB0051210010305_,5.428648956,-0.63947907,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,vancomycin,DB00512
,53776,DB00514,10010305,24,2142,33,1503,0.014213357,0.510399285,0.287387747,0.894276358,0.047150639,DB0051410010305_,3.054407724,-0.672561947,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,dextromethorphan,DB00514
,53780,DB00868,10010305,34,2950,16,1630,0.657939766,1.174090706,0.628398936,2.285218549,0.790952721,DB0086810010305_,0.234517084,0.160493981,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,benzonatate,DB00868
,53781,DB00874,10010305,28,3307,38,1938,0.000780217,0.431878979,0.254402082,0.725080283,0.004480663,DB0087410010305_,5.407984261,-0.839609871,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,guaifenesin,DB00874
,53782,DB00927,10010305,111,7386,71,4945,0.81932273,1.0467,0.7683557,1.433721116,0.903692583,DB0092710010305_,0.101266039,0.045642358,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,famotidine,DB00927
,53785,DB00319,10016288,44,1348,45,1808,0.232316932,1.311316636,0.84009044,2.045791972,0.388752713,DB0031910016288_,0.944811838,0.271031698,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,piperacillin,DB00319
,53786,DB00327,10016288,27,6111,56,4206,1.45930346346071e-06,0.331877911,0.201193319,0.535300821,2.0093133335288e-05,DB0032710016288_,10.81513243,-1.102988117,male,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,hydromorphone,DB00327
,53790,DB00582,10016288,40,1090,49,1525,0.585156005,1.14204879,0.727267465,1.784200792,0.73269939,DB0058210016288_,0.311019771,0.132823834,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,voriconazole,DB00582
,53793,DB00695,10016288,86,27963,103,20425,0.000853744,0.609892645,0.452385101,0.820499921,0.004832186,DB0069510016288_,5.332456301,-0.494472329,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,furosemide,DB00695
,53794,DB00868,10016288,28,2956,33,1613,0.002943048,0.463067033,0.268544613,0.793463579,0.013294476,DB0086810016288_,4.320406684,-0.769883455,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,benzonatate,DB00868
,53796,DB00927,10016288,81,7416,78,4938,0.022462557,0.691504675,0.499291012,0.958188993,0.067632109,DB0092710016288_,2.693672424,-0.368885367,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,famotidine,DB00927
,53811,DB00695,10018092,81,27968,52,20476,0.48297109,1.140385348,0.794844056,1.648929232,0.647177153,DB0069510018092_,0.435135215,0.13136623,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,53813,DB00761,10018092,41,15266,21,8604,0.79188773,1.100379786,0.634894861,1.961396285,0.887301788,DB0076110018092_,0.11957012,0.09565538,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,53828,DB00497,10018852,35,19232,22,16353,0.289180732,1.352738893,0.771271578,2.421686538,0.454298712,DB0049710018852_,0.789000342,0.302131347,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,oxycodone,DB00497
,53835,DB00695,10018852,64,27985,65,20463,0.073864532,0.719978925,0.501508042,1.033324117,0.167961997,DB0069510018852_,1.784017536,-0.328533339,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,furosemide,DB00695
,53836,DB00761,10018852,38,15269,28,8597,0.304791746,0.764148302,0.456402319,1.293712813,0.471566957,DB0076110018852_,0.751694178,-0.268993395,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,potassium chloride,DB00761
,53845,DB00327,10033318,29,6109,34,4228,0.039739758,0.590361624,0.346392796,1.000064348,0.105149943,DB0032710033318_,2.252367915,-0.527020008,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,hydromorphone,DB00327
,53846,DB00332,10033318,24,2660,32,1624,0.005123844,0.45797476,0.257134881,0.805572991,0.020862866,DB0033210033318_,3.869784429,-0.780941205,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,ipratropium,DB00332
,53847,DB00497,10033318,54,19213,42,16333,0.683083926,1.093020007,0.71636781,1.677745838,0.808418727,DB0049710033318_,0.212675128,0.088944514,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,oxycodone,DB00497
,53855,DB00927,10033318,57,7440,36,4980,0.832298659,1.059815022,0.685095364,1.658911741,0.912529,DB0092710033318_,0.091535413,0.058094385,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,famotidine,DB00927
,53856,DB01075,10033318,97,19851,41,11056,0.154343703,1.317654807,0.905000265,1.949121415,0.289945986,DB0107510033318_,1.238060629,0.275853495,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,diphenhydramine,DB01075
,53858,DB00099,10033661,49,2336,69,1886,0.003503874,0.573427773,0.387228822,0.843595314,0.015334552,DB0009910033661_,4.177646678,-0.556123291,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,filgrastim,DB00099
,53859,DB00327,10033661,36,6102,33,4229,0.26957592,0.756086946,0.457402369,1.253492058,0.432140212,DB0032710033661_,0.839005178,-0.279598901,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,hydromorphone,DB00327
,53860,DB00421,10033661,32,8871,19,5233,1,0.993514676,0.545645647,1.857143031,1,DB0042110033661_,0,-0.006506445,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,spironolactone,DB00421
,53861,DB00433,10033661,110,7546,95,5925,0.523752899,0.909167694,0.683059307,1.211958332,0.681847649,DB0043310033661_,0.382949034,-0.09522572,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,prochlorperazine,DB00433
,53866,DB00694,10033661,21,613,36,735,0.222617333,0.699604558,0.383715643,1.246101478,0.376726,DB0069410033661_,0.976237145,-0.35724002,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,daunorubicin,DB00694
,53868,DB00761,10033661,109,15198,96,8529,0.001620105,0.637170378,0.479196107,0.84842039,0.008181713,DB0076110033661_,4.805853769,-0.45071819,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,potassium chloride,DB00761
,53871,DB00927,10033661,56,7441,48,4968,0.227934592,0.77895305,0.519317677,1.172314322,0.383306472,DB0092710033661_,0.958920422,-0.249804504,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,famotidine,DB00927
,53872,DB00987,10033661,96,2008,171,2757,0.048138641,0.770851181,0.589969866,1.002521739,0.121589793,DB0098710033661_,2.107102254,-0.260259945,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,cytarabine,DB00987
,53873,DB01075,10033661,59,19889,60,11037,0.00106521,0.545671713,0.374117914,0.795700856,0.00580171,DB0107510033661_,5.149602505,-0.605737743,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,diphenhydramine,DB01075
,53876,DB00327,10035598,51,6087,30,4232,0.498005561,1.181885802,0.737197893,1.925466536,0.660081963,DB0032710035598_,0.415391266,0.1671113,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydromorphone,DB00327
,53877,DB00421,10035598,108,8795,53,5199,0.28683963,1.204510314,0.857663105,1.709707383,0.451607049,DB0042110035598_,0.794942839,0.186073106,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,53881,DB00588,10035598,99,16425,62,8406,0.211422312,0.817220135,0.588324187,1.142712417,0.363087483,DB0058810035598_,1.013111474,-0.201846777,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,53887,DB00927,10035598,62,7435,38,4978,0.758755372,1.092410899,0.716717445,1.684453667,0.865450973,DB0092710035598_,0.144504552,0.088387088,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,53903,DB00695,10042361,46,28003,55,20473,0.015236582,0.611485032,0.403962211,0.921802502,0.049924403,DB0069510042361_,2.997245349,-0.491864802,NA,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,53904,DB00761,10042361,32,15275,29,8596,0.081568749,0.620948803,0.363574761,1.064735005,0.180992282,DB0076110042361_,1.709300888,-0.476506643,NA,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,53917,DB00421,10047461,40,8863,17,5235,0.274742338,1.389752044,0.769305837,2.617195184,0.437964846,DB0042110047461_,0.825616633,0.329125346,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,spironolactone,DB00421
,53919,DB00497,10047461,43,19224,22,16353,0.060999033,1.662617027,0.972348473,2.919780637,0.145304236,DB0049710047461_,1.928925557,0.508392883,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,oxycodone,DB00497
,53925,DB00588,10047461,68,16456,33,8435,0.833914459,1.056220384,0.686525583,1.654492912,0.913709813,DB0058810047461_,0.09024225,0.05469686,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,53928,DB00695,10047461,94,27955,46,20482,0.025732318,1.4971968,1.040952511,2.180341541,0.075102597,DB0069510047461_,2.588900145,0.40359456,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,53930,DB00761,10047461,54,15253,20,8605,0.115525437,1.523183109,0.896284407,2.688296467,0.234485414,DB0076110047461_,1.450361895,0.420802296,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,53931,DB00787,10047461,65,16935,66,17182,1,0.999212694,0.697904316,1.430242014,1,DB0078710047461_,0,-0.000787616,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,acyclovir,DB00787
,53936,DB01075,10047461,75,19873,39,11058,0.769740449,1.070067799,0.716832865,1.619898421,0.873904099,DB0107510047461_,0.134784636,0.06772201,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,53940,DB00316,10060945,75,65399,37,36916,0.555228535,1.144222838,0.761788207,1.745712582,0.708696258,DB0031610060945_,0.344328253,0.134725663,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,53955,DB00695,10060945,57,27992,21,20507,0.005772646,1.988451683,1.186549159,3.454875875,0.022958691,DB0069510060945_,3.774058724,0.687356287,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,53957,DB00761,10060945,34,15273,17,8608,0.771150334,1.127229821,0.612083784,2.15284394,0.874711368,DB0076110060945_,0.133861312,0.119763137,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,53982,DB00381,10012373,96,29264,58,22829,0.142974478,1.291201343,0.922009217,1.821948907,0.274012698,DB0038110012373_,1.294580829,0.255573059,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,53988,DB01156,10012373,37,13585,33,6295,0.006799745,0.519542809,0.315795572,0.858128775,0.026193491,DB0115610012373_,3.642244322,-0.654806068,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,53991,DB00165,10013968,128,2017,46,1320,0.000436638,1.820748557,1.28038108,2.628219972,0.002757906,DB0016510013968_,5.893283406,0.599247712,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pyridoxine,DB00165
,53993,DB01024,10013968,93,2118,49,2071,0.000447452,1.855573383,1.291689422,2.693885627,0.002815389,DB0102410013968_,5.872654856,0.61819375,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolic acid,DB01024
,54011,DB00158,10042772,81,16734,51,8053,0.136643278,0.764354151,0.53130065,1.108512528,0.265018894,DB0015810042772_,1.327954158,-0.268724049,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,54013,DB00338,10042772,224,33450,189,22083,0.0153491,0.782448006,0.641354627,0.955382605,0.05021171,DB0033810042772_,2.991507005,-0.245327805,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,54018,DB01611,10042772,63,11850,10,2351,0.635670965,1.249879578,0.635627838,2.736428643,0.77357991,DB0161110042772_,0.256726304,0.223047209,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,hydroxychloroquine,DB01611
,54025,DB00928,10013968,17,818,35,1251,0.388876903,0.742923104,0.387569263,1.372742041,0.558742178,DB0092810013968_,0.582067132,-0.297162733,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azacitidine,DB00928
,54026,DB00928,10016256,28,807,43,1243,1,1.002966992,0.594854632,1.667165586,1,DB0092810016256_,0,0.002962599,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,azacitidine,DB00928
,54032,DB00814,10033425,248,8039,87,3328,0.200587985,1.180059716,0.917511137,1.52965114,0.349747871,DB0081410033425_,1.050542752,0.165565044,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,54036,DB00863,10001760,133,10540,25,5815,5.59358353170424e-08,2.934921826,1.901339046,4.703673775,1.07045754008625e-06,DB0086310001760_,13.74742439,1.076680818,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,54038,DB00007,10019211,102,1845,78,4374,1.87088906862757e-13,3.099563949,2.273390687,4.239442903,9.27855078658031e-12,DB0000710019211_,25.40331575,1.13126144,female,10019211,Headache,10029205,Nervous system disorders,Nerv,leuprolide,DB00007
,54048,DB14513,10006002,53,7124,15,3549,0.052863607,1.760135615,0.975785546,3.36693087,0.130434611,DB1451310006002_,2.036883241,0.56539086,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,54049,DB00169,10020583,83,38608,48,18127,0.260686773,0.811891511,0.562055756,1.184317298,0.422164489,DB0016910020583_,0.862360257,-0.208388555,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,54064,DB00864,10020575,41,6828,26,8366,0.009343945,1.932013737,1.152565806,3.293199147,0.033713877,DB0086410020575_,3.389845737,0.658562846,NA,10020575,Hyperammonaemia,10027433,Metabolism and nutrition disorders,Metab,tacrolimus,DB00864
,54066,DB00864,10021097,86,6783,137,8255,0.057439671,0.763978693,0.575365604,1.009775808,0.138609295,DB0086410021097_,1.976096128,-0.269215378,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,tacrolimus,DB00864
,54071,DB00864,10043071,48,6821,55,8337,0.766230832,1.066669316,0.707889244,1.602532172,0.871255485,DB0086410043071_,0.137820022,0.064541005,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,tacrolimus,DB00864
,54073,DB00864,10048294,59,6810,94,8298,0.120580032,0.764818748,0.541810988,1.072158711,0.242210549,DB0086410048294_,1.417947895,-0.268116404,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,tacrolimus,DB00864
,54075,DB00864,10070863,149,6720,181,8211,0.955471619,1.005852949,0.802319089,1.25948092,0.9931676,DB0086410070863_,0.006855848,0.005835887,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,tacrolimus,DB00864
,54106,DB00760,10035664,35,745,35,980,0.270315009,1.315220165,0.791042155,2.1867912,0.4330213,DB0076010035664_,0.836968359,0.274004078,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,meropenem,DB00760
,54108,DB01141,10035664,16,382,35,570,0.241544729,0.682374042,0.347485783,1.286692472,0.399630677,DB0114110035664_,0.917214465,-0.382177322,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,micafungin,DB01141
,54122,DB00472,10069326,46,10713,10,4302,0.076805725,1.847148721,0.918399564,4.109015581,0.172875363,DB0047210069326_,1.75518439,0.613643218,NA,10069326,Product substitution issue,10077536,Product issues,Prod,fluoxetine,DB00472
,54124,DB00196,10001760,58,5025,10,3275,1.47414817747315e-05,3.779609339,1.911783026,8.306930666,0.000152646,DB0019610001760_,8.787387364,1.329620655,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,fluconazole,DB00196
,54125,DB00999,10001760,312,21118,31,12208,2.38517411863746e-31,5.818854408,4.012748239,8.716479845,5.84839311835792e-29,DB0099910001760_,65.00880075,1.761103405,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,54126,DB00196,10003239,108,4975,27,3258,1.86252516136248e-06,2.619221728,1.700384589,4.164828551,2.48889038466765e-05,DB0019610003239_,10.60108848,0.962877223,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fluconazole,DB00196
,54127,DB00196,10003549,119,4964,99,3186,0.067456695,0.771518194,0.583678368,1.021590916,0.156793493,DB0019610003549_,1.852825669,-0.259395025,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,54128,DB00196,10003988,114,4969,32,3253,1.04864643006545e-05,2.332001604,1.559238621,3.577547347,0.000113105,DB0019610003988_,9.087194587,0.846726956,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fluconazole,DB00196
,54131,DB00999,10006002,104,21326,25,12214,3.18476333905708e-05,2.382491986,1.526830391,3.8514505,0.000299183,DB0099910006002_,8.114453926,0.868146993,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,54132,DB01076,10011224,493,25254,362,25221,9.83132237464133e-06,1.360085447,1.183759302,1.563905007,0.000107005,DB0107610011224_,9.142637961,0.307547526,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,54137,DB01076,10027940,27,25720,30,25553,0.69299382,0.894158642,0.51130197,1.556671194,0.815002163,DB0107610027940_,0.204564511,-0.111872067,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,54142,DB09053,10018884,34,2251,64,3988,0.832504416,0.941196961,0.599908946,1.453608785,0.912697486,DB0905310018884_,0.091350794,-0.060602852,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ibrutinib,DB09053
,54147,DB01254,10013968,168,3299,129,3019,0.153656681,1.19175907,0.936542644,1.519299824,0.289027183,DB0125410013968_,1.241234537,0.175430426,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dasatinib,DB01254
,54155,DB00531,10066260,28,7224,32,6484,0.366819658,0.785385051,0.455075745,1.348230176,0.536448366,DB0053110066260_,0.622784963,-0.241581171,NA,10066260,Acute graft versus host disease,10021428,Immune system disorders,Immun,cyclophosphamide,DB00531
,54159,DB00715,10019211,255,4588,54,2233,4.94866471464547e-09,2.298097222,1.699361457,3.156442746,1.18953499793741e-07,DB0071510019211_,15.94453318,0.832081486,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,paroxetine,DB00715
,54160,DB01137,10019211,275,7497,89,5504,2.28575551492597e-12,2.268317156,1.775053585,2.921998659,9.72973015543791e-11,DB0113710019211_,23.05324986,0.819038216,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,54164,DB01254,10011906,144,3323,171,2977,0.0151983,0.754459472,0.596773794,0.952706198,0.049834397,DB0125410011906_,2.999049832,-0.281753717,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dasatinib,DB01254
,54165,DB00398,10010305,21,706,56,1482,0.386992382,0.787290853,0.449014544,1.333162412,0.557115577,DB0039810010305_,0.584982562,-0.239157527,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,sorafenib,DB00398
,54171,DB13961,10035598,40,9417,39,6375,0.108563737,0.694356755,0.434848014,1.109503568,0.223870916,DB1396110035598_,1.49668566,-0.364769394,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,54175,DB00480,10047340,86,67342,56,67606,0.011678147,1.541721106,1.088309012,2.199234164,0.040291409,DB0048010047340_,3.211617013,0.432899394,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,lenalidomide,DB00480
,54178,DB01098,10005470,17,8132,46,7163,3.6083828543458e-05,0.325550541,0.174833675,0.579427313,0.000333672,DB0109810005470_,8.005351268,-1.122237557,male,10005470,Blood creatine phosphokinase increased,10022891,Investigations,Inv,rosuvastatin,DB01098
,54180,DB01098,10039020,57,8092,105,7104,5.26700476795125e-06,0.476595586,0.338458086,0.665250325,6.18911382171615e-05,DB0109810039020_,9.690133551,-0.741086975,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,54182,DB00051,10030124,91,25640,26,11394,0.045087672,1.555326297,0.995837022,2.507966935,0.115746603,DB0005110030124_,2.156351937,0.441685361,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,54186,DB01238,10013710,71,5179,95,3407,6.50684929258522e-06,0.491688507,0.355209052,0.677971007,7.44753031376453e-05,DB0123810013710_,9.505042989,-0.709909878,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,54187,DB14509,10013710,33,852,26,525,0.412231125,0.782245655,0.448032577,1.378634789,0.581615412,DB1450910013710_,0.541945854,-0.245586451,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,lithium carbonate,DB14509
,54196,DB00285,10029412,43,10908,17,3701,0.55579244,0.858241974,0.478686144,1.607167823,0.709174966,DB0028510029412_,0.343653005,-0.152869199,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,54197,DB00285,10033664,60,10891,11,3707,0.056075532,1.856612586,0.965753743,3.920668138,0.136211566,DB0028510033664_,1.99354597,0.618753637,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,54198,DB00285,10061284,35,10916,15,3703,0.420376731,0.791537629,0.420689916,1.561871423,0.58932679,DB0028510061284_,0.528774427,-0.233777859,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,54211,DB00695,10005725,65,27984,69,20459,0.035262382,0.68873097,0.482891709,0.981265197,0.095979261,DB0069510005725_,2.343623142,-0.372904549,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,furosemide,DB00695
,54212,DB00722,10005725,43,25360,78,25954,0.002543921,0.564203859,0.379317918,0.829340638,0.011818129,DB0072210005725_,4.438120546,-0.572339641,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,lisinopril,DB00722
,54213,DB00761,10005725,30,15277,25,8600,0.160104373,0.675566317,0.383764201,1.19876124,0.297619763,DB0076110005725_,1.211938571,-0.392203952,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,potassium chloride,DB00761
,54218,DB00153,10012174,87,7336,58,3381,0.03825884,0.691330496,0.488943272,0.983700073,0.102141447,DB0015310012174_,2.281396689,-0.369137283,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ergocalciferol,DB00153
,54219,DB00575,10012174,61,5183,43,3786,0.920576734,1.036241105,0.688319969,1.572169563,0.964812755,DB0057510012174_,0.035821232,0.035599843,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,clonidine,DB00575
,54220,DB01175,10012174,117,10607,69,4823,0.094819324,0.770997745,0.566622576,1.055972396,0.202955276,DB0117510012174_,1.59476964,-0.26006983,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,escitalopram,DB01175
,54221,DB01224,10012174,63,8045,36,5881,0.261950836,1.279250089,0.835057827,1.986598434,0.423650375,DB0122410012174_,0.85884675,0.246274038,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,quetiapine,DB01224
,54233,DB00175,10038153,31,8100,23,6083,1,1.012200419,0.570741536,1.819779051,1,DB0017510038153_,0,0.012126593,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,pravastatin,DB00175
,54235,DB00316,10038153,216,65258,129,36824,0.61360702,0.944847489,0.755899402,1.184887869,0.755334638,DB0031610038153_,0.280594399,-0.056731752,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,54237,DB00761,10038153,91,15216,54,8571,0.794789107,0.949248151,0.669829618,1.356514413,0.88886159,DB0076110038153_,0.117813747,-0.052085028,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,54238,DB00999,10038153,87,21343,45,12194,0.650565443,1.104590707,0.761609691,1.621443882,0.785075072,DB0099910038153_,0.241975933,0.099474865,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,54242,DB00153,10041349,91,7332,34,3405,0.333358523,1.242907209,0.82785365,1.905672056,0.502383899,DB0015310041349_,0.688390712,0.217453159,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,54243,DB00175,10041349,100,8031,56,6050,0.087336977,1.345204999,0.958631057,1.903958834,0.190652973,DB0017510041349_,1.657300399,0.296546417,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,54244,DB00575,10041349,124,5120,53,3776,0.000901019,1.725366197,1.237445775,2.43420088,0.005056209,DB0057510041349_,5.287138306,0.545439316,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,54245,DB00761,10041349,154,15153,82,8543,0.73344144,1.058813669,0.803635215,1.403535465,0.845381756,DB0076110041349_,0.167966972,0.057149101,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,54247,DB00046,10000081,76,5383,54,4638,0.289474569,1.212600262,0.842338701,1.756121477,0.454625463,DB0004610000081_,0.788281358,0.192767031,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,insulin lispro,DB00046
,54248,DB00165,10000081,47,2098,13,1353,0.004957029,2.331057676,1.235045167,4.714403634,0.020330085,DB0016510000081_,3.895653465,0.846322103,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,pyridoxine,DB00165
,54249,DB00641,10000081,140,13984,142,12333,0.254579349,0.869520544,0.682634256,1.107449087,0.415276112,DB0064110000081_,0.878811649,-0.139813319,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,54253,DB00115,10001949,97,18328,44,10428,0.220261818,1.254334095,0.868984752,1.835847962,0.373774615,DB0011510001949_,0.984102298,0.22660483,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,54254,DB00158,10001949,66,16749,21,8083,0.108229818,1.516706711,0.915441791,2.611938646,0.223403548,DB0015810001949_,1.498775512,0.416541347,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,54256,DB00641,10001949,71,14053,40,12435,0.022186172,1.570603194,1.050615406,2.377267913,0.067049558,DB0064110001949_,2.702323267,0.451459746,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,54257,DB00727,10001949,33,3810,24,4149,0.144152979,1.497255971,0.856738682,2.652819431,0.275788707,DB0072710001949_,1.288120259,0.40363408,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,54260,DB00047,10007559,101,9184,132,8386,0.008149344,0.698686246,0.532861522,0.913892312,0.030248606,DB0004710007559_,3.49830517,-0.358553498,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,insulin glargine,DB00047
,54263,DB01377,10007559,54,3742,61,2609,0.012643038,0.617274795,0.418382742,0.908509169,0.042919056,DB0137710007559_,3.148439345,-0.482440981,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,magnesium oxide,DB01377
,54264,DB00046,10011224,99,5360,62,4630,0.055546987,1.379257151,0.991509421,1.931285633,0.135258934,DB0004610011224_,2.000564309,0.321545058,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin lispro,DB00046
,54265,DB00047,10011224,154,9131,100,8418,0.006500697,1.419715912,1.094618815,1.848296789,0.025248735,DB0004710011224_,3.678979237,0.35045679,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,54266,DB00115,10011224,390,18035,181,10291,0.022266212,1.229445587,1.026377052,1.477245113,0.06722189,DB0011510011224_,2.699756334,0.206563326,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,54267,DB00165,10011224,43,2102,29,1337,0.8081282,0.943141009,0.572270455,1.574827911,0.896477889,DB0016510011224_,0.10928165,-0.058539476,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pyridoxine,DB00165
,54268,DB00727,10011224,82,3761,68,4105,0.099429122,1.316127158,0.939574553,1.848623582,0.210003573,DB0072710011224_,1.560630732,0.274693453,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nitroglycerin,DB00727
,54270,DB01254,10011224,67,3400,43,3105,0.082826084,1.42286884,0.952673031,2.145070764,0.18310977,DB0125410011224_,1.697669469,0.352675143,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dasatinib,DB01254
,54271,DB01377,10011224,100,3696,47,2623,0.021942039,1.509876682,1.053174112,2.191619303,0.066502912,DB0137710011224_,2.71050955,0.41202798,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium oxide,DB01377
,54272,DB00727,10013968,239,3604,230,3943,0.182502553,1.136853911,0.939156749,1.376421656,0.327043878,DB0072710013968_,1.117660934,0.128264721,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nitroglycerin,DB00727
,54273,DB00843,10013968,53,2141,50,2123,0.842232802,1.051094592,0.697087963,1.586829412,0.919665828,DB0084310013968_,0.083744906,0.04983209,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,donepezil,DB00843
,54274,DB01377,10013968,246,3550,124,2546,0.001903852,1.42272169,1.134702271,1.790915688,0.009346797,DB0137710013968_,4.672721514,0.35257172,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium oxide,DB01377
,54278,DB00641,10018836,50,14074,34,12441,0.273627103,1.29994171,0.823650621,2.074126512,0.436649005,DB0064110018836_,0.828625599,0.262319425,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,54281,DB00047,10042674,73,9212,44,8474,0.032291826,1.52613499,1.034519482,2.274368923,0.089743143,DB0004710042674_,2.410803653,0.422738389,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,54282,DB00115,10042674,154,18271,46,10426,6.20988818501416e-05,1.910333027,1.364926063,2.719219701,0.000530749,DB0011510042674_,7.541221992,0.647277587,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,54284,DB00727,10042674,44,3799,6,4167,4.01156404823594e-09,8.041935846,3.409161334,23.11786242,9.84078030871503e-08,DB0072710042674_,16.13414574,2.084669831,female,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,54286,DB01254,10042674,36,3431,24,3124,0.245702913,1.365715614,0.790600068,2.398834122,0.404579407,DB0125410042674_,0.904907253,0.31167855,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,dasatinib,DB01254
,54296,DB00047,10047899,166,9119,91,8427,5.3806751006356e-05,1.68569153,1.295309317,2.205265615,0.000469793,DB0004710047899_,7.663219359,0.522175883,NA,10047899,Weight increased,10022891,Investigations,Inv,insulin glargine,DB00047
,54297,DB00165,10047899,44,2101,18,1348,0.115960864,1.568163065,0.88337852,2.896301757,0.235096899,DB0016510047899_,1.447757512,0.449904912,NA,10047899,Weight increased,10022891,Investigations,Inv,pyridoxine,DB00165
,54298,DB00727,10047899,60,3783,43,4130,0.037188779,1.52324669,1.009915425,2.314836296,0.099936341,DB0072710047899_,2.303221887,0.420844037,NA,10047899,Weight increased,10022891,Investigations,Inv,nitroglycerin,DB00727
,54300,DB01254,10047899,50,3417,22,3126,0.00413075,2.078882752,1.232667739,3.614073404,0.01753784,DB0125410047899_,4.043394426,0.731830611,NA,10047899,Weight increased,10022891,Investigations,Inv,dasatinib,DB01254
,54301,DB01377,10047899,57,3739,30,2640,0.227810184,1.341475067,0.845052953,2.168787422,0.383157838,DB0137710047899_,0.959308264,0.293769805,NA,10047899,Weight increased,10022891,Investigations,Inv,magnesium oxide,DB01377
,54304,DB01254,10053762,115,3352,82,3066,0.095781925,1.282729476,0.953576691,1.731822641,0.204452485,DB0125410053762_,1.587419677,0.24899021,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,dasatinib,DB01254
,54313,DB01115,10013968,303,3297,114,2154,6.43445362981964e-07,1.736299879,1.385357463,2.188132718,9.68114560159183e-06,DB0111510013968_,11.54533032,0.551756343,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nifedipine,DB01115
,54314,DB01216,10013968,11,225,286,6829,0.612164434,1.167323113,0.567892071,2.161396104,0.754070912,DB0121610013968_,0.282268868,0.15471319,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,finasteride,DB01216
,54315,DB04854,10013968,31,750,40,1446,0.100372063,1.493974259,0.895652748,2.471293396,0.211383677,DB0485410013968_,1.554080422,0.401439857,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,febuxostat,DB04854
,54320,DB08910,10062237,56,16688,58,17430,1,1.008447482,0.685424156,1.482680192,1,DB0891010062237_,0,0.008412002,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,pomalidomide,DB08910
,54323,DB01076,10002383,37,25710,53,25530,0.09176944,0.693233875,0.442662565,1.075438739,0.198075881,DB0107610002383_,1.619105084,-0.366387854,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,54328,DB00678,10005750,258,15341,129,10595,0.00292891,1.381248461,1.112128859,1.722382002,0.013248391,DB0067810005750_,4.323879204,0.322987772,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,losartan,DB00678
,54330,DB00381,10005802,63,29297,25,22862,0.003538717,1.966445543,1.219038457,3.263455287,0.015453593,DB0038110005802_,4.169913755,0.67622762,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,amlodipine,DB00381
,54333,DB00999,10005802,54,21376,22,12217,0.190968066,1.40282988,0.839672841,2.420259333,0.337769708,DB0099910005802_,1.085390954,0.338491539,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,54335,DB00175,10013911,50,8081,54,6052,0.073033591,0.693470532,0.461710859,1.039790508,0.166578312,DB0017510013911_,1.79228974,-0.366046531,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,54337,DB00999,10013911,135,21295,85,12154,0.482567218,0.906480982,0.685269859,1.204700317,0.646926063,DB0099910013911_,0.435523267,-0.098185229,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,54338,DB01156,10013911,58,13564,20,6308,0.274111644,1.348684925,0.798337715,2.369493364,0.437211357,DB0115610013911_,0.827338545,0.299129988,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,54339,DB01268,10013911,174,1969,252,2878,0.958978555,1.009238246,0.820010028,1.240037986,0.996629421,DB0126810013911_,0.003376272,0.009195834,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,sunitinib,DB01268
,54341,DB00381,10016766,132,29228,94,22793,0.545521,1.095113513,0.833713325,1.443179273,0.70028421,DB0038110016766_,0.356269012,0.090858023,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,54343,DB00678,10016766,80,15519,51,10673,0.721776254,1.078815344,0.749259414,1.565709007,0.836058645,DB0067810016766_,0.179056519,0.075863536,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,54345,DB01268,10016766,38,2105,44,3086,0.308641749,1.266048898,0.795167153,2.007533969,0.475996619,DB0126810016766_,0.742344527,0.235900947,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,54347,DB00381,10018388,37,29323,23,22864,0.436086939,1.254340777,0.725639127,2.211618343,0.604686826,DB0038110018388_,0.503044597,0.226610158,NA,10018388,Glossodynia,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,54349,DB00999,10018388,36,21394,15,12224,0.382125015,1.371287969,0.731899883,2.697090882,0.552210458,DB0099910018388_,0.593826042,0.315750421,NA,10018388,Glossodynia,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,54351,DB00175,10022437,158,7973,88,6018,0.022990576,1.355174833,1.035285751,1.783423146,0.068894408,DB0017510022437_,2.675180271,0.303930474,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,pravastatin,DB00175
,54352,DB00575,10022437,97,5147,86,3743,0.198743059,0.820259109,0.605259887,1.113187123,0.347522705,DB0057510022437_,1.056925277,-0.198135003,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,clonidine,DB00575
,54353,DB00678,10022437,295,15304,157,10567,0.009073324,1.297372505,1.063637081,1.58732541,0.03294548,DB0067810022437_,3.41290119,0.26034107,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,losartan,DB00678
,54354,DB01268,10022437,49,2094,71,3059,1,1.008185356,0.682836085,1.478130966,1,DB0126810022437_,0,0.008152037,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,sunitinib,DB01268
,54355,DB00381,10036018,79,29281,73,22814,0.325948411,0.843184415,0.605253924,1.176006601,0.49446263,DB0038110036018_,0.704283701,-0.170569585,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,54357,DB00678,10036018,38,15561,38,10686,0.102941972,0.686741516,0.426039233,1.106976606,0.215397637,DB0067810036018_,1.535269485,-0.375797308,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,losartan,DB00678
,54360,DB00175,10042128,55,8076,26,6080,0.055327074,1.592510811,0.980511991,2.649127716,0.134892138,DB0017510042128_,2.003279801,0.465311897,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,54361,DB00381,10042128,147,29213,79,22808,0.007158551,1.452772461,1.097202243,1.935739513,0.027269928,DB0038110042128_,3.601970739,0.373473773,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,54363,DB00678,10042128,88,15511,35,10689,0.00561723,1.732615916,1.157784834,2.644193421,0.02246123,DB0067810042128_,3.795964589,0.549632356,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,54372,DB00381,10074170,37,29323,23,22864,0.436086939,1.254340777,0.725639127,2.211618343,0.604686826,DB0038110074170_,0.503044597,0.226610158,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,54378,DB00153,10017944,39,7384,14,3425,0.461807036,1.292055842,0.685219256,2.579942027,0.628981197,DB0015310017944_,0.463653916,0.256234626,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,54379,DB00863,10017944,55,10618,27,5813,0.728617029,1.115216037,0.690657004,1.841042288,0.841801345,DB0086310017944_,0.172211224,0.109048142,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,54380,DB00904,10017944,131,22938,54,14402,0.009837146,1.523140389,1.100524697,2.133422496,0.035105474,DB0090410017944_,3.349398193,0.420774249,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,54381,DB01050,10017944,95,18013,25,9346,0.001895199,1.971576591,1.256984446,3.20016422,0.009306051,DB0105010017944_,4.677090398,0.678833523,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,54392,DB01254,10047942,37,3430,29,3119,0.62077432,1.160152334,0.692450831,1.960946781,0.761234103,DB0125410047942_,0.272814343,0.148551319,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,dasatinib,DB01254
,54397,DB00332,10013573,79,2605,42,1614,0.449213533,1.165396292,0.78720988,1.746538793,0.616834119,DB0033210013573_,0.483155142,0.153061194,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ipratropium,DB00332
,54398,DB00590,10013573,24,752,70,1882,0.562771078,0.858106988,0.511935406,1.393910547,0.714990467,DB0059010013573_,0.335486069,-0.153026492,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,doxazosin,DB00590
,54399,DB00646,10013573,87,3366,36,1964,0.088922215,1.409996446,0.941686808,2.150046684,0.193478781,DB0064610013573_,1.642587432,0.343587183,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,nystatin,DB00646
,54403,DB09153,10013573,177,7622,100,5599,0.042350271,1.300188146,1.009179382,1.682786029,0.110390407,DB0915310013573_,2.203732042,0.262508981,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,54415,DB00480,10027864,71,67357,70,67592,0.933024257,1.017826694,0.721098827,1.43697068,0.973721907,DB0048010027864_,0.026629532,0.017669662,NA,10027864,Monoclonal immunoglobulin present,10022891,Investigations,Inv,lenalidomide,DB00480
,54429,DB01234,10027864,33,31592,34,32854,1,1.009360743,0.605779799,1.680101764,1,DB0123410027864_,0,0.009317203,NA,10027864,Monoclonal immunoglobulin present,10022891,Investigations,Inv,dexamethasone,DB01234
,54433,DB00381,10033661,89,29271,98,22789,0.018190295,0.707065831,0.524336712,0.952393687,0.057330644,DB0038110033661_,2.858919991,-0.346631504,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,amlodipine,DB00381
,54434,DB00531,10033661,168,7084,241,6275,2.09725781925521e-06,0.61751473,0.502519314,0.75741122,2.76420587423411e-05,DB0053110033661_,10.49617208,-0.482052356,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,cyclophosphamide,DB00531
,54438,DB00904,10033661,175,22894,176,14280,9.6452336383821e-06,0.620231296,0.499675541,0.769788862,0.000105354,DB0090410033661_,9.158185106,-0.477662812,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,ondansetron,DB00904
,54439,DB00997,10033661,115,5216,158,3356,1.07861429915914e-09,0.46833626,0.363582626,0.601793348,2.97340082363902e-08,DB0099710033661_,17.33097439,-0.758568736,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,doxorubicin,DB00997
,54440,DB01042,10033661,17,973,37,1291,0.096470892,0.60974683,0.319932218,1.11805153,0.205464279,DB0104210033661_,1.582483086,-0.494711441,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,melphalan,DB01042
,54441,DB01060,10033661,20,8567,37,5044,2.49914604753486e-05,0.318282111,0.174816328,0.56348512,0.000241463,DB0106010033661_,8.328793625,-1.144817148,male,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,amoxicillin,DB01060
,54447,DB00316,10041834,24,65450,47,36906,3.29786490209526e-07,0.28794278,0.168391518,0.480571039,5.32132467474364e-06,DB0031610041834_,12.14378829,-1.244993499,male,10041834,Squamous cell carcinoma of skin,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,54457,DB00787,10041834,17,16983,50,17198,6.82193940641275e-05,0.344291241,0.186073491,0.607603301,0.000574103,DB0078710041834_,7.462701473,-1.066267349,male,10041834,Squamous cell carcinoma of skin,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acyclovir,DB00787
,54497,DB00425,10001053,42,12653,45,7439,0.005356873,0.548770708,0.351264805,0.855705847,0.021610836,DB0042510001053_,3.834560405,-0.600074578,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,54498,DB00476,10001053,35,17222,17,6160,0.343611853,0.736414597,0.401323991,1.402814561,0.512893885,DB0047610001053_,0.667686306,-0.305962007,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,54502,DB05679,10002855,34,6897,27,4882,0.696633197,0.891369361,0.521275154,1.538159535,0.817493979,DB0567910002855_,0.201511742,-0.11499639,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ustekinumab,DB05679
,54503,DB00476,10007559,69,17188,44,6133,0.003631071,0.559584187,0.377456659,0.837291659,0.015784785,DB0047610007559_,4.148708756,-0.580561295,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,duloxetine,DB00476
,54506,DB00268,10012378,73,2902,12,1533,4.04187571122173e-05,3.212903512,1.725739294,6.521784932,0.000367997,DB0026810012378_,7.907436062,1.167175049,female,10012378,Depression,10037175,Psychiatric disorders,Psych,ropinirole,DB00268
,54508,DB05679,10012378,42,6889,29,4880,1,1.025923131,0.623175653,1.710379131,1,DB0567910012378_,0,0.025592822,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ustekinumab,DB05679
,54510,DB00425,10037423,46,12649,15,7469,0.046319787,1.810759435,0.99199477,3.494265955,0.11813085,DB0042510037423_,2.135962368,0.593746334,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,54511,DB00476,10037423,34,17223,19,6158,0.120086793,0.639831242,0.354446161,1.188377368,0.241505841,DB0047610037423_,1.42086162,-0.446550821,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,54528,DB00678,10013710,105,15494,96,10628,0.043749648,0.750269349,0.562757316,1.00119403,0.113085133,DB0067810013710_,2.179614351,-0.287323005,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,54529,DB14726,10013710,21,1996,46,2802,0.104395873,0.640925557,0.362095181,1.099956486,0.217587157,DB1472610013710_,1.525155788,-0.444841965,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,dabigatran,DB14726
,54534,DB00213,10018867,34,18861,50,13371,0.001170158,0.482072531,0.302190207,0.760753639,0.006272579,DB0021310018867_,5.071567653,-0.729660698,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,54540,DB00108,10028335,52,10142,19,3276,0.677747875,0.884029206,0.513032694,1.585781055,0.804710413,DB0010810028335_,0.217272802,-0.123265178,NA,10028335,Muscle spasticity,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,54542,DB00005,10033474,101,127981,34,42385,0.920835579,0.983804856,0.660963594,1.49729774,0.964924382,DB0000510033474_,0.035705541,-0.016327719,NA,10033474,Pain of skin,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,54545,DB00230,10010264,872,18802,285,8366,6.67414999192979e-06,1.361417132,1.186550166,1.56560509,7.61911107656349e-05,DB0023010010264_,9.482265759,0.308526166,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,54546,DB00787,10010264,78,16922,58,17190,0.08534288,1.366108168,0.959401412,1.954804752,0.187311111,DB0078710010264_,1.674984347,0.311965944,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,54550,DB00230,10011469,134,19540,15,8636,3.29692888578948e-09,3.948466461,2.308241827,7.255487653,8.2541248020657e-08,DB0023010011469_,16.30996769,1.373327266,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,54556,DB00471,10019211,846,13343,189,5276,2.82516146552481e-13,1.769899772,1.504886054,2.089993503,1.36883629716718e-11,DB0047110019211_,25.01447506,0.570922919,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,54557,DB00787,10019211,459,16541,188,17060,1.51348303878899e-28,2.518075173,2.117467715,3.004012822,3.04842158425813e-26,DB0078710019211_,58.75258847,0.923494789,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,54558,DB00953,10019211,148,1549,15,217,0.313078356,1.382011804,0.792458499,2.580085864,0.480625195,DB0095310019211_,0.732667532,0.323540266,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,rizatriptan,DB00953
,54560,DB01202,10019211,242,6472,135,5583,5.14049493233198e-05,1.546302483,1.243615867,1.929164338,0.000452429,DB0120210019211_,7.700879799,0.435866586,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,54561,DB00213,10022437,335,18560,157,13264,1.12359817108481e-05,1.524880252,1.2560957,1.857649228,0.000120007,DB0021310022437_,9.027958614,0.421915884,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,54562,DB00230,10022437,913,18761,337,8314,0.00469886,1.200563704,1.05550615,1.368071421,0.019456449,DB0023010022437_,3.939576694,0.1827912,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,54563,DB00471,10022437,196,13993,77,5388,0.891836215,0.980126877,0.747810878,1.295464767,0.955019756,DB0047110022437_,0.046023252,-0.020073249,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,montelukast,DB00471
,54564,DB00787,10022437,234,16766,170,17078,0.000933385,1.40206501,1.144467084,1.720474096,0.005202297,DB0078710022437_,5.258654997,0.337946157,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,acyclovir,DB00787
,54566,DB00989,10022437,33,801,22,856,0.100187018,1.602544538,0.898032864,2.91173896,0.211053157,DB0098910022437_,1.555645249,0.471592702,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,rivastigmine,DB00989
,54579,DB00230,10048439,266,19408,24,8627,5.03717239049366e-20,4.926776596,3.237048863,7.830389848,5.2332836475939e-18,DB0023010048439_,39.79149274,1.59468494,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,54580,DB00471,10048439,47,14142,6,5459,0.00541326,3.023882687,1.289164814,8.659346523,0.02179316,DB0047110048439_,3.826159133,1.106541664,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,54599,DB06186,10008531,12,2197,38,3608,0.05570522,0.5186552,0.246161998,1.016544801,0.135554497,DB0618610008531_,1.998381529,-0.656515971,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,ipilimumab,DB06186
,54600,DB08911,10008531,80,1559,112,1636,0.062854574,0.749630526,0.550690278,1.016690246,0.148698838,DB0891110008531_,1.905832237,-0.288174825,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,trametinib,DB08911
,54601,DB08912,10008531,80,1250,113,1421,0.156183615,0.804875862,0.590553405,1.092878601,0.292357665,DB0891210008531_,1.229777347,-0.217067222,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,dabrafenib,DB08912
,54602,DB00335,10010305,88,8378,82,5383,0.017592659,0.689566867,0.503516997,0.945167616,0.055902204,DB0033510010305_,2.884151468,-0.371691607,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,atenolol,DB00335
,54603,DB06186,10010305,32,2177,40,3606,0.270783448,1.325032323,0.803074631,2.170443672,0.433481101,DB0618610010305_,0.835907081,0.281436854,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ipilimumab,DB06186
,54606,DB06186,10011906,199,2010,316,3330,0.668464918,1.043277804,0.861757465,1.260849047,0.798551101,DB0618610011906_,0.224956317,0.042367491,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ipilimumab,DB06186
,54607,DB08911,10011906,186,1453,255,1493,0.005759664,0.749558989,0.608603278,0.92189916,0.022917465,DB0891110011906_,3.775855981,-0.288270259,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,trametinib,DB08911
,54608,DB08912,10011906,160,1170,239,1295,0.006785117,0.741059057,0.593436137,0.923674402,0.026144805,DB0891210011906_,3.644104767,-0.299674958,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dabrafenib,DB08912
,54609,DB00335,10012174,138,8328,76,5389,0.289970282,1.174936816,0.87971772,1.579259651,0.455200003,DB0033510012174_,0.787018389,0.161214372,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,atenolol,DB00335
,54610,DB08911,10012174,45,1594,62,1686,0.201585057,0.767758784,0.507816319,1.152945563,0.350986204,DB0891110012174_,1.047008362,-0.264279678,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,trametinib,DB08911
,54611,DB08912,10012174,33,1297,44,1490,0.563565934,0.861648684,0.528108607,1.39379177,0.715481577,DB0891210012174_,0.334799429,-0.148907651,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,dabrafenib,DB08912
,54612,DB00316,10012239,35,65439,36,36917,0.012987524,0.548504423,0.334376643,0.898882248,0.043844988,DB0031610012239_,3.127094874,-0.600559935,NA,10012239,Delusion,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,54624,DB00399,10013968,262,6730,129,4869,0.000380895,1.469339951,1.181541777,1.834623598,0.002462326,DB0039910013968_,6.006648809,0.384813287,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zoledronic acid,DB00399
,54625,DB06186,10013968,82,2127,122,3524,0.462950664,1.11355918,0.826784284,1.49358091,0.630124962,DB0618610013968_,0.461837128,0.107561354,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipilimumab,DB06186
,54646,DB00335,10021036,34,8432,29,5436,0.301071842,0.75586831,0.446348771,1.287623969,0.467338315,DB0033510021036_,0.760701841,-0.279888112,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,atenolol,DB00335
,54648,DB06186,10021036,37,2172,87,3559,0.074980426,0.696909294,0.459256979,1.039300281,0.169806853,DB0618610021036_,1.773093647,-0.361100015,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,ipilimumab,DB06186
,54651,DB00316,10021425,76,65398,22,36931,0.004370855,1.950807916,1.200222969,3.294298827,0.018348307,DB0031610021425_,3.998217976,0.668243602,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,acetaminophen,DB00316
,54658,DB00327,10021789,68,6070,43,4219,0.698166066,1.099173705,0.73776905,1.653366379,0.818481172,DB0032710021789_,0.200304885,0.094558721,NA,10021789,Infection,10021881,Infections and infestations,Infec,hydromorphone,DB00327
,54659,DB00335,10021789,62,8404,41,5424,0.919529553,0.975971603,0.646334281,1.487720866,0.964382416,DB0033510021789_,0.036267366,-0.024321789,NA,10021789,Infection,10021881,Infections and infestations,Infec,atenolol,DB00335
,54665,DB06186,10033371,24,2185,33,3613,0.49518633,1.202530067,0.678135334,2.103575821,0.657505187,DB0618610033371_,0.419302626,0.184427727,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ipilimumab,DB06186
,54669,DB08911,10037660,231,1408,292,1456,0.036385204,0.81811549,0.674878773,0.990921725,0.098326971,DB0891110037660_,2.319456912,-0.200751767,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,trametinib,DB08911
,54670,DB08912,10037660,225,1105,286,1248,0.240352854,0.888560338,0.729171712,1.081897879,0.398231503,DB0891210037660_,0.920721776,-0.118152723,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,dabrafenib,DB08912
,54671,DB00399,10040047,57,6935,69,4929,0.003502796,0.587176252,0.40521653,0.847942123,0.015332811,DB0039910040047_,4.177760237,-0.532430246,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,zoledronic acid,DB00399
,54672,DB08911,10040047,33,1606,24,1724,0.180993405,1.475848,0.842075311,2.621986226,0.325105385,DB0891110040047_,1.123605888,0.38923274,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,trametinib,DB08911
,54674,DB00327,10040070,32,6106,30,4232,0.245512366,0.739327824,0.434344409,1.261573279,0.404354306,DB0032710040070_,0.905463789,-0.302013852,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,hydromorphone,DB00327
,54686,DB00327,10044565,51,6087,29,4233,0.425525859,1.222942093,0.759158727,2.004684434,0.594235086,DB0032710044565_,0.520480271,0.201259507,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,54687,DB00399,10044565,86,6906,41,4957,0.037020328,1.505539835,1.024348357,2.244919018,0.099637007,DB0039910044565_,2.306221626,0.409151528,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,zoledronic acid,DB00399
,54698,DB00327,10048959,77,6061,41,4221,0.187551353,1.307876649,0.882169058,1.964111099,0.333499345,DB0032710048959_,1.098114376,0.268404944,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,54699,DB00399,10048959,175,6817,93,4905,0.020319622,1.35390992,1.043930313,1.765282363,0.06258877,DB0039910048959_,2.771169405,0.302996644,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,54710,DB00316,10061520,134,65340,45,36908,0.002287293,1.682020906,1.191477575,2.413985743,0.010855195,DB0031610061520_,4.523111547,0.519995991,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,54717,DB00327,10061623,66,6072,31,4231,0.077686313,1.483465129,0.952371031,2.356632142,0.174446606,DB0032710061623_,1.746136567,0.394380655,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,54718,DB00335,10061623,59,8407,44,5421,0.479371141,0.864657513,0.57437767,1.310181781,0.644411171,DB0033510061623_,0.439418293,-0.145421789,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,54734,DB00316,10067973,63,65411,69,36884,0.000176279,0.514836375,0.359900931,0.735371334,0.001296435,DB0031610067973_,6.648137452,-0.663906147,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,54740,DB08868,10003549,279,8923,75,2436,0.947627507,1.015570263,0.781076475,1.333964298,0.986119365,DB0886810003549_,0.013977872,0.01545029,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,54741,DB00181,10007882,64,9792,35,5836,0.754798121,1.089828419,0.709897564,1.698094713,0.862329068,DB0018110007882_,0.148118331,0.08602027,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,baclofen,DB00181
,54743,DB00181,10025256,73,9783,19,5852,0.000729659,2.298161414,1.370554163,4.037280705,0.004235698,DB0018110025256_,5.464207155,0.832109418,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,baclofen,DB00181
,54744,DB08868,10025256,687,8515,181,2330,0.698916585,1.038622106,0.874588341,1.238162978,0.818987281,DB0886810025256_,0.199686725,0.037894937,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,fingolimod,DB08868
,54752,DB00635,10007632,39,33014,12,23782,0.009861157,2.341119734,1.200634243,4.912006977,0.03516729,DB0063510007632_,3.347638897,0.850629334,NA,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,prednisone,DB00635
,54755,DB00374,10008531,203,17513,63,5661,0.829652663,1.041592713,0.780132817,1.407069089,0.910634524,DB0037410008531_,0.093613644,0.040750996,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,54756,DB06403,10008531,160,21311,47,6614,0.805666504,1.056502587,0.757944282,1.497374106,0.894882379,DB0640310008531_,0.111062989,0.054964007,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,54757,DB00993,10011224,63,3186,25,1594,0.362431995,1.260686633,0.778350598,2.100139022,0.53213378,DB0099310011224_,0.630860356,0.23165652,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azathioprine,DB00993
,54758,DB00993,10013968,155,3094,60,1559,0.103090209,1.301640349,0.953771702,1.795447127,0.215639515,DB0099310013968_,1.534147176,0.263625276,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azathioprine,DB00993
,54759,DB00421,10013971,192,8711,44,5208,6.04219743922882e-10,2.608706253,1.867854087,3.71432066,1.74718547513894e-08,DB0042110013971_,17.86267455,0.95885441,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,54761,DB00993,10019211,149,3100,33,1586,5.80862404343575e-06,2.309669239,1.566747802,3.494959782,6.73590264665324e-05,DB0099310019211_,9.605473641,0.837104328,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,azathioprine,DB00993
,54762,DB00421,10019303,105,8798,34,5218,0.001908375,1.83152603,1.231388438,2.786330424,0.009365504,DB0042110019303_,4.670722175,0.605149516,NA,10019303,Heart rate increased,10022891,Investigations,Inv,spironolactone,DB00421
,54763,DB00635,10019303,196,32857,89,23705,0.000232824,1.588816926,1.229829707,2.065947854,0.001635647,DB0063510019303_,6.415716887,0.462989668,NA,10019303,Heart rate increased,10022891,Investigations,Inv,prednisone,DB00635
,54765,DB00374,10024264,92,17624,51,5673,0.002401114,0.580681201,0.407486409,0.835590732,0.011296455,DB0037410024264_,4.483266311,-0.543553379,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,54766,DB00421,10024264,57,8846,38,5214,0.594495145,0.884139492,0.575444689,1.372139884,0.740390177,DB0042110024264_,0.300577966,-0.123140432,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,54767,DB00635,10024264,97,32956,99,23695,0.016489467,0.704480044,0.526609414,0.942211339,0.053068409,DB0063510024264_,2.936173457,-0.350295275,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,54769,DB06403,10024264,79,21392,24,6637,1,1.021265092,0.639134989,1.688321347,1,DB0640310024264_,0,0.021042145,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,54772,DB00695,10033546,34,28015,24,20504,1,1.036852693,0.596840331,1.82804636,1,DB0069510033546_,0,0.036189868,NA,10033546,Pallor,10047065,Vascular disorders,Vasc,furosemide,DB00695
,54775,DB06403,10033557,560,20911,81,6580,1.6915811315748e-12,2.175560147,1.717572013,2.786119538,7.32507578969415e-11,DB0640310033557_,23.33713252,0.77728617,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,ambrisentan,DB06403
,54776,DB00421,10036790,95,8808,18,5234,1.0837523741503e-06,3.136009707,1.878801013,5.523912455,1.53565666601297e-05,DB0042110036790_,11.08396738,1.142951198,female,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,54778,DB00421,10037423,117,8786,43,5209,0.006567696,1.613119889,1.12617084,2.34867416,0.025452544,DB0042110037423_,3.670939571,0.478170123,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,54779,DB00635,10037423,163,32890,93,23701,0.07551388,1.263006195,0.972494783,1.648390764,0.170654486,DB0063510037423_,1.768114314,0.233494749,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,54782,DB00635,10043521,102,32951,32,23762,1.49450722638428e-05,2.298554352,1.53123556,3.535812383,0.000154536,DB0063510043521_,8.775081665,0.832280383,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,54783,DB00695,10043521,76,27973,22,20506,5.30574644063873e-05,2.532328924,1.557695784,4.27743476,0.000464717,DB0069510043521_,7.67408213,0.929139403,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,54785,DB00421,10065154,52,8851,28,5224,0.729249491,1.096120777,0.678643497,1.804933064,0.842274653,DB0042110065154_,0.171649126,0.09177738,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,spironolactone,DB00421
,54786,DB00635,10065154,210,32843,154,23640,0.873052258,0.981524076,0.792913778,1.217223443,0.944641609,DB0063510065154_,0.056949673,-0.018648736,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,prednisone,DB00635
,54787,DB00695,10065154,185,27864,114,20414,0.158721846,1.188901725,0.935699969,1.51603328,0.295792386,DB0069510065154_,1.218097469,0.173029961,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,furosemide,DB00695
,54789,DB06403,10065154,132,21339,40,6621,1,1.023920721,0.713108079,1.499083934,1,DB0640310065154_,0,0.023639102,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,ambrisentan,DB06403
,54792,DB00203,10033425,682,13196,287,8651,2.82523330217093e-10,1.557822195,1.351402313,1.799301198,8.60002980284458e-09,DB0020310033425_,18.57150017,0.443288817,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,54795,DB01276,10069327,67,1950,55,1456,0.641910498,0.909601148,0.622887229,1.332979016,0.778454748,DB0127610069327_,0.250444416,-0.094749075,NA,10069327,Product quality issue,10077536,Product issues,Prod,exenatide,DB01276
,54796,DB00175,10002855,123,8008,47,6059,4.4768712296343e-05,1.979979927,1.401450435,2.83832014,0.000402237,DB0017510002855_,7.818468021,0.683086707,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,pravastatin,DB00175
,54797,DB00966,10013968,42,671,11,423,0.008672059,2.405367598,1.200565171,5.240120751,0.031775991,DB0096610013968_,3.449044259,0.877702739,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,telmisartan,DB00966
,54804,DB00264,10029216,100,29507,41,24851,6.21304727420723e-05,2.054097407,1.414176227,3.032530216,0.000530917,DB0026410029216_,7.540905602,0.719836533,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,54806,DB00999,10029216,103,21327,22,12217,5.89056664390039e-06,2.681864472,1.679106169,4.467269701,6.81635677899721e-05,DB0099910029216_,9.593600332,0.986512251,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,54807,DB00175,10033557,70,8061,21,6085,0.000107568,2.51604646,1.524501558,4.320311093,0.000849206,DB0017510033557_,7.071209244,0.922688805,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,pravastatin,DB00175
,54808,DB00264,10033557,318,29289,120,24772,4.38029770860448e-15,2.241220397,1.809895977,2.790380408,2.7059018865022e-13,DB0026410033557_,28.93817094,0.807020538,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,metoprolol,DB00264
,54811,DB00264,10033664,52,29555,24,24868,0.015141855,1.823040174,1.10345394,3.093009663,0.049688288,DB0026410033664_,3.001986024,0.600505533,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,54812,DB00404,10033664,123,19769,36,9826,0.005126832,1.698195127,1.161938724,2.537592145,0.020871799,DB0040410033664_,3.869356353,0.529565997,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,54814,DB00999,10033664,40,21390,11,12228,0.028721999,2.07875374,1.046317417,4.493799021,0.0818693,DB0099910033664_,2.5026312,0.731768551,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,54816,DB00404,10048010,107,19785,61,9801,0.411153024,0.868948588,0.628040131,1.211572007,0.580508268,DB0040410048010_,0.543851235,-0.140471317,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,54818,DB00999,10048010,71,21359,16,12223,0.000317282,2.539360054,1.460530421,4.682566202,0.002111596,DB0099910048010_,6.160311405,0.931912102,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,54821,DB01261,10003549,102,3679,91,3212,0.883988048,0.978596593,0.727325279,1.318358508,0.951636223,DB0126110003549_,0.049572436,-0.021635782,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,54824,DB01261,10008629,33,3748,48,3255,0.024791924,0.59711862,0.370339315,0.952211863,0.073031012,DB0126110008629_,2.616871108,-0.515639492,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,sitagliptin,DB01261
,54827,DB01261,10018884,41,3740,37,3266,0.909501095,0.967662644,0.603550647,1.556086027,0.959357771,DB0126110018884_,0.041491207,-0.032871761,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,sitagliptin,DB01261
,54828,DB01261,10020993,43,3738,62,3241,0.010436726,0.601385077,0.39664125,0.904513733,0.036817789,DB0126110020993_,3.301774144,-0.508519823,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,sitagliptin,DB01261
,54830,DB01261,10027457,63,3718,87,3216,0.004900758,0.626414214,0.443985906,0.879573071,0.020140156,DB0126110027457_,3.905039658,-0.467743443,NA,10027457,Metastases to liver,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sitagliptin,DB01261
,54834,DB01261,10033610,76,3705,105,3198,0.001945624,0.624810728,0.457051272,0.850822151,0.00952164,DB0126110033610_,4.654188129,-0.47030651,NA,10033610,Pancreatic carcinoma metastatic,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sitagliptin,DB01261
,54842,DB00682,10028810,454,19005,150,16214,2.26661827521102e-26,2.582013176,2.139641265,3.130522562,3.88130692924572e-24,DB0068210028810_,53.9058703,0.948569396,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,warfarin,DB00682
,54846,DB00451,10019465,57,47214,9,15410,0.04410617,2.066973311,1.015668322,4.751011209,0.113782577,DB0045110019465_,2.173465869,0.726085369,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,54853,DB00108,10035664,246,9948,80,3215,0.948040845,0.99378054,0.766650966,1.299713122,0.986490909,DB0010810035664_,0.013601169,-0.006238882,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,natalizumab,DB00108
,54854,DB00153,10035664,207,7216,149,3290,4.6756595588315e-05,0.633431152,0.508555066,0.790528772,0.000417175,DB0015310035664_,7.782005114,-0.456603965,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ergocalciferol,DB00153
,54872,DB00115,10060933,64,18361,36,10436,1,1.010450701,0.661035392,1.566317185,1,DB0011510060933_,0,0.01039647,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,54874,DB01175,10060933,36,10688,20,4872,0.473193987,0.820539528,0.461890169,1.497577496,0.639168733,DB0117510060933_,0.447586802,-0.197793194,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,54876,DB00005,10048038,80,128002,30,42389,0.581232541,0.883076045,0.573769467,1.39231608,0.729593952,DB0000510048038_,0.31526713,-0.124343961,NA,10048038,Wound infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,54891,DB00829,10013754,93,7959,65,4389,0.155245287,0.789030984,0.567260636,1.102965587,0.291140294,DB0082910013754_,1.233950016,-0.236949689,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,54894,DB00181,10013781,42,9814,24,5847,0.89939666,1.04261791,0.616247773,1.801906388,0.956490275,DB0018110013781_,0.044484657,0.041734771,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,baclofen,DB00181
,54895,DB00230,10013781,162,19512,54,8597,0.087765925,1.321743937,0.96477716,1.835562471,0.191454197,DB0023010013781_,1.653106681,0.278952029,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,54896,DB00370,10013781,31,4510,19,3644,0.393059617,1.318241724,0.720191727,2.474065045,0.563030751,DB0037010013781_,0.574421032,0.276298822,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,mirtazapine,DB00370
,54897,DB00557,10013781,44,5943,17,3050,0.345390771,1.328290631,0.742255434,2.483995491,0.514834774,DB0055710013781_,0.663909257,0.283892876,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,hydroxyzine,DB00557
,54898,DB00829,10013781,40,8012,19,4435,0.683080765,1.165324562,0.658421634,2.133113986,0.808418727,DB0082910013781_,0.212675128,0.152999642,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,diazepam,DB00829
,54899,DB01068,10013781,79,13684,37,6803,0.843389898,1.061478453,0.708866047,1.615697268,0.920618915,DB0106810013781_,0.082709102,0.059662703,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,54908,DB00996,10019022,38,38915,25,22400,0.602715763,0.874938751,0.514420158,1.512702528,0.746560346,DB0099610019022_,0.292278826,-0.133601393,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,54912,DB00370,10021789,35,4506,30,3633,0.803750013,0.940662952,0.559822464,1.58941699,0.893811228,DB0037010021789_,0.112260681,-0.061170384,NA,10021789,Infection,10021881,Infections and infestations,Infec,mirtazapine,DB00370
,54913,DB00404,10021789,137,19755,42,9820,0.005244428,1.62143379,1.138922605,2.351184548,0.021255073,DB0040410021789_,3.851159669,0.483310813,NA,10021789,Infection,10021881,Infections and infestations,Infec,alprazolam,DB00404
,54914,DB00425,10021789,101,12594,53,7431,0.504459152,1.124434865,0.797572068,1.601019189,0.665480994,DB0042510021789_,0.4072452,0.117280567,NA,10021789,Infection,10021881,Infections and infestations,Infec,zolpidem,DB00425
,54915,DB00557,10021789,45,5942,17,3050,0.345943116,1.358689907,0.76100293,2.536749551,0.515351232,DB0055710021789_,0.662906608,0.306520932,NA,10021789,Infection,10021881,Infections and infestations,Infec,hydroxyzine,DB00557
,54916,DB00829,10021789,72,7980,33,4421,0.413429865,1.208695962,0.788637608,1.887761697,0.582852585,DB0082910021789_,0.539820981,0.189542061,NA,10021789,Infection,10021881,Infections and infestations,Infec,diazepam,DB00829
,54917,DB00996,10021789,374,38579,175,22250,0.023149477,1.232607869,1.026495676,1.48469776,0.069260031,DB0099610021789_,2.66988729,0.209132143,NA,10021789,Infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,54918,DB01062,10021789,36,4450,22,1723,0.105320526,0.633636014,0.361606436,1.134155058,0.219073571,DB0106210021789_,1.518347667,-0.4562806,NA,10021789,Infection,10021881,Infections and infestations,Infec,oxybutynin,DB01062
,54920,DB00370,10028334,41,4500,36,3627,0.730705517,0.917954527,0.570952545,1.481664313,0.843350648,DB0037010028334_,0.170372454,-0.085607425,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,mirtazapine,DB00370
,54921,DB00829,10028334,188,7864,72,4382,0.007191052,1.454929198,1.100195976,1.941655131,0.027358056,DB0082910028334_,3.59874424,0.374957238,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,diazepam,DB00829
,54928,DB00829,10028335,27,8025,31,4423,0.005727269,0.480056206,0.275266427,0.832377723,0.022813958,DB0082910028335_,3.780382728,-0.733852086,NA,10028335,Muscle spasticity,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,54930,DB00370,10033295,65,4476,57,3606,0.647589599,0.918710898,0.631950367,1.338779544,0.782795705,DB0037010033295_,0.24488353,-0.084783789,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,mirtazapine,DB00370
,54932,DB01062,10033425,109,4377,23,1722,0.005858145,1.864308605,1.17602881,3.0747284,0.023230194,DB0106210033425_,3.762302391,0.622890263,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,oxybutynin,DB01062
,54944,DB00996,10037087,697,38256,262,22163,1.28946116830975e-09,1.541194369,1.333876346,1.784965864,3.50682739876065e-08,DB0099610037087_,17.16596899,0.43255768,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,54945,DB01062,10037087,90,4396,21,1724,0.032625291,1.680643588,1.03226119,2.855751588,0.090473784,DB0106210037087_,2.402695145,0.519176808,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,oxybutynin,DB01062
,54946,DB01068,10037087,203,13560,67,6773,0.003338363,1.513332914,1.140936308,2.028930762,0.014746469,DB0106810037087_,4.216751646,0.414314446,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,clonazepam,DB01068
,54947,DB09020,10037087,34,1920,20,1584,0.270752912,1.402367189,0.780897327,2.582065691,0.433458617,DB0902010037087_,0.83595895,0.338161658,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,bisacodyl,DB09020
,54948,DB00370,10044565,75,4466,42,3621,0.060881717,1.447777719,0.976745133,2.171361242,0.145064219,DB0037010044565_,1.930578744,0.370029773,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,mirtazapine,DB00370
,54949,DB00425,10044565,149,12546,86,7398,0.892191228,1.021637317,0.777021674,1.350387821,0.955096007,DB0042510044565_,0.045943412,0.021406553,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,54950,DB00557,10044565,91,5896,41,3026,0.51801702,1.139092967,0.777413902,1.694259497,0.677438866,DB0055710044565_,0.389435965,0.130232303,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,54951,DB00829,10044565,119,7933,48,4406,0.073138553,1.37689924,0.97485235,1.97162496,0.166750401,DB0082910044565_,1.791257187,0.319834043,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,54952,DB01062,10044565,66,4420,26,1719,1,0.987245107,0.61603861,1.625446983,1,DB0106210044565_,0,-0.012836935,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,54953,DB01068,10044565,279,13484,126,6714,0.393957647,1.102535751,0.88829488,1.374672994,0.563899951,DB0106810044565_,0.572878435,0.097612755,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,54977,DB00404,10057362,33,19859,21,9841,0.386595628,0.77874262,0.43703346,1.417106066,0.556716894,DB0040410057362_,0.585698438,-0.250074685,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,54981,DB00996,10057362,76,38877,42,22383,0.92381215,1.041815047,0.705297119,1.557619109,0.966829343,DB0099610057362_,0.03373328,0.04096443,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,54982,DB01068,10057362,39,13724,35,6805,0.012924876,0.552504587,0.340696788,0.899183812,0.043675562,DB0106810057362_,3.13096655,-0.593293543,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,55004,DB00327,10013709,271,5867,137,4125,0.002028719,1.390729981,1.123717735,1.727425393,0.009836511,DB0032710013709_,4.621654237,0.329828775,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,55006,DB00433,10023547,46,7610,41,5979,0.588799543,0.881500483,0.565126018,1.379189477,0.735597138,DB0043310023547_,0.307072677,-0.126129729,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,prochlorperazine,DB00433
,55008,DB01175,10035226,48,10676,32,4860,0.115324552,0.682850257,0.427029189,1.105254106,0.234140952,DB0117510035226_,1.451831985,-0.381479687,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,escitalopram,DB01175
,55009,DB00068,10013709,96,2138,22,643,0.313956826,1.312227025,0.811043642,2.20982654,0.481498902,DB0006810013709_,0.730851329,0.271725713,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,55017,DB01016,10047895,21,1080,42,1186,0.029105823,0.549212459,0.306871571,0.955524002,0.082724574,DB0101610047895_,2.49223858,-0.599269919,NA,10047895,Weight decreased,10022891,Investigations,Inv,glyburide,DB01016
,55018,DB01020,10047895,30,1783,44,1834,0.158554492,0.701390191,0.423695387,1.146905904,0.295553848,DB0102010047895_,1.218904231,-0.354690926,NA,10047895,Weight decreased,10022891,Investigations,Inv,isosorbide mononitrate,DB01020
,55021,DB09140,10047895,178,3563,77,1721,0.451887368,1.116581517,0.844351576,1.487855229,0.619465649,DB0914010047895_,0.478898029,0.110271801,NA,10047895,Weight decreased,10022891,Investigations,Inv,oxygen,DB09140
,55022,DB00661,10013573,106,3422,37,1558,0.1994322,1.304329082,0.88462011,1.960805773,0.348368526,DB0066110013573_,1.054494378,0.265688795,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,verapamil,DB00661
,55023,DB00678,10013573,592,15007,379,10345,0.27237395,1.076772949,0.942540944,1.231240251,0.435324655,DB0067810013573_,0.831663194,0.073968558,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,losartan,DB00678
,55026,DB11133,10013573,82,2349,59,1515,0.539717697,0.89640515,0.629471264,1.283048205,0.695466807,DB1113310013573_,0.363171994,-0.109362792,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,omega-3 fatty acids,DB11133
,55027,DB00661,10016322,52,3476,12,1583,0.030057683,1.973210806,1.035867074,4.073487594,0.084825661,DB0066110016322_,2.467157171,0.679662067,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,verapamil,DB00661
,55028,DB00758,10016322,118,8182,102,9972,0.011666101,1.409912271,1.070673044,1.859203596,0.040260418,DB0075810016322_,3.212386475,0.343527483,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,55031,DB11133,10016322,38,2393,14,1560,0.085348638,1.769210141,0.933349994,3.547217243,0.187315907,DB1113310016322_,1.674958747,0.570533199,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,55032,DB00758,10019211,340,7960,192,9882,1.33771765449863e-18,2.198337047,1.831789472,2.64432614,1.22089960237835e-16,DB0075810019211_,36.64177352,0.787701187,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,55035,DB11133,10019211,125,2306,39,1535,2.69739548296932e-05,2.133130977,1.468721422,3.158232653,0.000258198,DB1113310019211_,8.261785667,0.757590843,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,omega-3 fatty acids,DB11133
,55036,DB00264,10049848,204,29403,151,24741,0.239988538,1.136771567,0.915903237,1.41345799,0.397849247,DB0026410049848_,0.921682123,0.128192286,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,55037,DB00338,10049848,239,33435,147,22125,0.498081402,1.075887363,0.871772267,1.33138304,0.660112392,DB0033810049848_,0.415345168,0.073145775,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,55039,DB00678,10049848,126,15473,93,10631,0.628983091,0.9308691,0.705574522,1.231831786,0.768093128,DB0067810049848_,0.263844292,-0.071636613,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,losartan,DB00678
,55040,DB00695,10049848,207,27842,141,20387,0.549218524,1.075003559,0.863022266,1.342254769,0.703578901,DB0069510049848_,0.351575254,0.072323973,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,55041,DB00758,10049848,60,8240,74,10000,1,0.98399339,0.68719863,1.403998669,1,DB0075810049848_,0,-0.0161361,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,55046,DB00563,10005734,47,46599,25,15323,0.055754191,0.618200056,0.372701193,1.048514826,0.135625276,DB0056310005734_,1.997859522,-0.480943159,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,methotrexate,DB00563
,55054,DB06285,10013968,124,8726,26,1080,0.018373447,0.590318304,0.382297692,0.943528697,0.057791792,DB0628510013968_,2.850908524,-0.527093389,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,teriparatide,DB06285
,55061,DB00051,10031161,236,25495,52,11368,1.27918886784011e-06,2.023627497,1.491968894,2.79024492,1.78279318086836e-05,DB0005110031161_,10.93474413,0.704891692,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,55063,DB00722,10031161,106,25297,33,25999,1.18259690817577e-10,3.30143593,2.21407308,5.040979573,3.80471967336598e-09,DB0072210031161_,19.38702352,1.194357504,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,55065,DB00051,10039073,799,24932,175,11245,5.76098523727084e-20,2.05922443,1.743574501,2.442922199,5.92220964259964e-18,DB0005110039073_,39.66782204,0.722329422,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,55066,DB00335,10039073,52,8414,16,5449,0.008487891,2.104628048,1.181401966,3.953425227,0.031227406,DB0033510039073_,3.466459166,0.744138752,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,55067,DB00722,10039073,162,25241,44,25988,6.1061886145782e-18,3.790319136,2.700432278,5.420137394,5.24513620046366e-16,DB0072210039073_,35.18406028,1.33245022,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,55068,DB01076,10039073,140,25607,41,25542,7.05808316267174e-14,3.40555132,2.388385951,4.951602618,3.69565171176946e-12,DB0107610039073_,26.3238642,1.225406841,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,55075,DB00051,10061024,71,25660,39,11381,0.300844228,0.807483188,0.538524999,1.226769932,0.467150526,DB0005110061024_,0.761103747,-0.213833044,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,adalimumab,DB00051
,55076,DB00563,10061024,74,46572,28,15320,0.565735642,0.869397801,0.555653805,1.395820882,0.71728043,DB0056310061024_,0.332288399,-0.139954489,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,methotrexate,DB00563
,55085,DB00115,10003983,40,18385,28,10444,0.448677751,0.811548874,0.488004764,1.366723536,0.616307993,DB0011510003983_,0.484008452,-0.208810668,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,55089,DB01373,10003983,51,22669,6,7375,0.012848289,2.765385295,1.185991474,7.88874338,0.043475448,DB0137310003983_,3.135558904,1.017179972,female,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,55094,DB00165,10025482,73,2072,25,1341,0.006054131,1.889507097,1.178277406,3.123222152,0.023834767,DB0016510025482_,3.736609965,0.636316,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,pyridoxine,DB00165
,55095,DB00334,10025482,53,2796,20,2792,0.000131558,2.645906805,1.550584759,4.685932423,0.001007778,DB0033410025482_,6.900006968,0.973013844,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,olanzapine,DB00334
,55096,DB01062,10025482,144,4342,37,1708,0.02302265,1.530881925,1.05514982,2.270626326,0.068955145,DB0106210025482_,2.674299059,0.425843991,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,55097,DB01307,10025482,60,2464,49,2020,1,1.00384233,0.673452539,1.502548035,1,DB0130710025482_,0,0.003834967,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,insulin detemir,DB01307
,55100,DB14500,10025482,322,7487,92,3981,6.49522006894312e-08,1.860936893,1.466714798,2.380272622,1.22516583790578e-06,DB1450010025482_,13.61243435,0.621080067,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,55105,DB00203,10034474,124,13754,51,8887,0.006398805,1.570974594,1.123881764,2.22399458,0.02492296,DB0020310034474_,3.691965802,0.451696187,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,sildenafil,DB00203
,55106,DB00559,10040070,39,9620,13,3293,1,1.026932842,0.535812964,2.099259495,1,DB0055910040070_,0,0.026576536,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,bosentan,DB00559
,55107,DB00471,10008469,217,13972,43,5422,2.58565848492933e-05,1.958301665,1.404142843,2.787763588,0.00024865,DB0047110008469_,8.299463708,0.6720776,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,55110,DB00016,10018879,51,2711,49,2241,0.478548889,0.860399761,0.567361813,1.305909711,0.643821244,DB0001610018879_,0.440334163,-0.15035816,NA,10018879,Haemoglobin abnormal,10022891,Investigations,Inv,erythropoietin,DB00016
,55127,DB00338,10013774,119,33555,27,22245,3.80910350062825e-08,2.921776883,1.910290094,4.618324238,7.53649119412973e-07,DB0033810013774_,14.09833894,1.072191953,female,10013774,Dry eye,10015919,Eye disorders,Eye,omeprazole,DB00338
,55132,DB00413,10016256,143,2056,74,1133,0.714055504,1.064892944,0.790821659,1.443511983,0.830429348,DB0041310016256_,0.185812425,0.062874272,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pramipexole,DB00413
,55133,DB00540,10016256,160,2323,49,1042,0.024527454,1.464533164,1.047709536,2.078020619,0.072448691,DB0054010016256_,2.624876681,0.381536532,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,nortriptyline,DB00540
,55134,DB00175,10033775,93,8038,37,6069,0.000916717,1.897705664,1.281457097,2.862439806,0.005128968,DB0017510033775_,5.272850743,0.640645611,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,55140,DB00177,10003239,112,4688,53,2797,0.19263957,1.260736803,0.898211217,1.788999275,0.33995979,DB0017710003239_,1.078927933,0.231696314,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,valsartan,DB00177
,55141,DB00761,10003239,378,14929,125,8500,7.62316558142592e-08,1.721712346,1.400289801,2.128568401,1.41707855238883e-06,DB0076110003239_,13.46691316,0.543319345,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,55142,DB00682,10006002,89,19370,26,16338,4.19698197762337e-07,2.887047136,1.846262704,4.660615881,6.60782697105902e-06,DB0068210006002_,11.92725571,1.060234228,female,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,55143,DB00761,10006002,75,15232,16,8609,0.000165735,2.64923551,1.528667296,4.873991811,0.001229734,DB0076110006002_,6.700957387,0.974271112,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,55145,DB01068,10006002,62,13701,21,6819,0.130688615,1.469376997,0.882424053,2.540403152,0.256756877,DB0106810006002_,1.359625647,0.384838499,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,55157,DB00177,10028411,67,4733,25,2825,0.050402929,1.599527237,0.994217272,2.650041136,0.125780024,DB0017710028411_,2.073220742,0.469708109,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,valsartan,DB00177
,55158,DB00682,10028411,308,19151,114,16250,2.66616039469224e-15,2.292372881,1.841367806,2.87060046,1.69890972059359e-13,DB0068210028411_,29.4036195,0.829587474,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,55159,DB00761,10028411,197,15110,60,8565,1.4469443892769e-05,1.86108962,1.38558757,2.53151111,0.000150298,DB0076110028411_,8.802889927,0.621162133,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,55161,DB01068,10028411,118,13645,52,6788,0.513254793,1.128864538,0.806889031,1.598195114,0.673249107,DB0106810028411_,0.395639874,0.121212294,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,55162,DB01136,10028411,100,9784,83,11032,0.044389922,1.35847195,1.003911237,1.84231106,0.114379876,DB0113610028411_,2.168230127,0.306360502,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,carvedilol,DB01136
,55164,DB00682,10038776,65,19394,19,16345,1.4345630859139e-05,2.883005906,1.706574394,5.094425704,0.000149263,DB0068210038776_,8.809802662,1.058833467,female,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,55172,DB01068,10048439,74,13689,9,6831,3.36596588204861e-06,4.102393919,2.046723599,9.32936317,4.18121045414214e-05,DB0106810048439_,10.08232468,1.411570686,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,55175,DB00331,10013781,112,24834,70,20682,0.062269174,1.332485577,0.979181783,1.823893401,0.14768297,DB0033110013781_,1.912687398,0.287046053,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,55200,DB00874,10012735,182,3153,81,1895,0.030652411,1.350354474,1.026943074,1.788217613,0.08614794,DB0087410012735_,2.451689224,0.300367131,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,guaifenesin,DB00874
,55201,DB06589,10012735,291,1739,448,2205,0.018950535,0.823649345,0.698906732,0.969653889,0.059218309,DB0658910012735_,2.826524512,-0.194010391,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pazopanib,DB06589
,55202,DB06724,10012735,572,7357,229,3690,0.005092847,1.252824696,1.067222857,1.474293102,0.020760777,DB0672410012735_,3.874689789,0.225400759,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,55204,DB06724,10035664,341,7588,208,3711,0.015670579,0.80181391,0.669706158,0.961683412,0.05102178,DB0672410035664_,2.97550268,-0.22087873,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,55205,DB00874,10048959,64,3271,32,1944,0.457341467,1.188631228,0.762835702,1.885291926,0.62468992,DB0087410048959_,0.470499881,0.172802416,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,55206,DB01306,10048959,86,4122,63,3803,0.185411816,1.259398582,0.896505162,1.777479998,0.330695538,DB0130610048959_,1.106557152,0.230634291,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,55208,DB06724,10048959,165,7764,46,3873,0.000370134,1.789241088,1.280230655,2.543999608,0.002403106,DB0672410048959_,6.030993242,0.581791557,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,55210,DB00193,10005555,42,19278,16,8686,0.670457125,1.182715649,0.650739406,2.254933025,0.800083838,DB0019310005555_,0.22303876,0.167813192,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,tramadol,DB00193
,55212,DB00451,10005555,117,47154,33,15386,0.507032074,1.156850537,0.779950685,1.758929059,0.667668857,DB0045110005555_,0.403962951,0.145701258,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,55213,DB00996,10005555,72,38881,56,22369,0.098068346,0.739721176,0.514218384,1.068818683,0.207955072,DB0099610005555_,1.570433223,-0.301481953,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,gabapentin,DB00996
,55226,DB00218,10016256,71,1371,28,922,0.020581864,1.704911495,1.07696818,2.765699496,0.063222425,DB0021810016256_,2.761096212,0.5335132,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,moxifloxacin,DB00218
,55229,DB00996,10025482,1088,37865,410,22015,2.93310215455911e-14,1.542846318,1.374198332,1.734778099,1.61628071556784e-12,DB0099610025482_,27.15089346,0.433628969,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,55233,DB00193,10060933,82,19238,28,8674,0.216792588,1.320369565,0.84975324,2.108444062,0.369593539,DB0019310060933_,0.995351422,0.277911671,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,55235,DB00451,10060933,175,47096,49,15370,0.392466061,1.165546937,0.844249422,1.635404307,0.562362103,DB0045110060933_,0.575609325,0.153190451,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,55236,DB00996,10060933,123,38830,54,22371,0.100875994,1.312282943,0.945111256,1.843086839,0.212126425,DB0099610060933_,1.550572836,0.271768325,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,55238,DB00722,10001053,75,25328,91,25941,0.31215705,0.84412658,0.613031846,1.159301847,0.479673091,DB0072210001053_,0.734650467,-0.169452819,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,55239,DB00213,10002424,35,18860,38,13383,0.074598799,0.653599138,0.400682247,1.063350681,0.16917557,DB0021310002424_,1.776818227,-0.425261055,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,55246,DB00108,10017577,298,9896,88,3207,0.471250415,1.097411747,0.859349367,1.413165771,0.63748891,DB0010810017577_,0.450218398,0.09295445,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,55247,DB00758,10017577,144,8156,93,9981,1.38842183489216e-06,1.894763936,1.447342637,2.490575573,1.92380959041331e-05,DB0075810017577_,10.85861808,0.639094259,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,55248,DB06637,10017577,517,5645,165,1854,0.780922682,1.029103271,0.85499936,1.24348287,0.880700697,DB0663710017577_,0.127037442,0.028687812,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,55249,DB13961,10017577,177,9280,82,6332,0.003991798,1.472793375,1.124939686,1.941681294,0.017055331,DB1396110017577_,4.07129244,0.387160853,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,55250,DB00722,10020937,291,25112,170,25862,3.02894684851017e-09,1.762856702,1.452775254,2.144454673,7.64801805120941e-08,DB0072210020937_,16.38623421,0.566935619,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,55251,DB00758,10020937,91,8209,57,10017,8.52224149016162e-05,1.948015412,1.381920001,2.766080405,0.000696107,DB0075810020937_,7.270007687,0.666811117,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,55252,DB01062,10020937,75,4411,15,1730,0.017399253,1.960826633,1.11265982,3.686758577,0.055401499,DB0106210020937_,2.893148626,0.673366136,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,55253,DB00108,10022004,48,10146,9,3286,0.163317171,1.727185669,0.837080536,4.008243895,0.301834472,DB0010810022004_,1.197876519,0.546493303,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,55254,DB00264,10022004,133,29474,85,24807,0.048325808,1.316937282,0.995112826,1.750855446,0.121937914,DB0026410022004_,2.104243263,0.2753088,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,55255,DB00641,10022004,80,14044,37,12438,0.001068734,1.914857231,1.280455988,2.911262132,0.005816259,DB0064110022004_,5.147098093,0.649643067,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,55256,DB00758,10022004,51,8249,37,10037,0.017903867,1.677075876,1.075790126,2.636855473,0.056658217,DB0075810022004_,2.870718248,0.517051727,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,55258,DB01373,10022004,154,22566,30,7351,0.009645184,1.672123981,1.12406559,2.564670648,0.034581647,DB0137310022004_,3.364432166,0.514094663,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,55259,DB06637,10022004,72,6090,33,1986,0.111103924,0.711541409,0.463474561,1.112980391,0.227726656,DB0663710022004_,1.479609246,-0.340321664,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,55260,DB08908,10022004,65,10608,14,3265,0.286323826,1.428954839,0.792423246,2.761127991,0.451065134,DB0890810022004_,0.796143529,0.356943295,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,55261,DB13961,10022004,67,9390,31,6383,0.079640992,1.469135962,0.945052789,2.3301752,0.177818091,DB1396110022004_,1.726994209,0.384674447,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,55262,DB00264,10028245,44,29563,18,24874,0.010189532,2.056664663,1.164009759,3.782908124,0.036100803,DB0026410028245_,3.321440158,0.721085575,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,55264,DB00722,10028245,51,25352,21,26011,0.000333417,2.491753194,1.471836774,4.36238785,0.002201974,DB0072210028245_,6.118401178,0.912986557,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,55266,DB01062,10028245,52,4434,15,1730,0.34048457,1.352480595,0.747443836,2.593918519,0.509702862,DB0106210028245_,0.673927346,0.301940384,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,55267,DB01373,10028245,51,22669,6,7375,0.012848289,2.765385295,1.185991474,7.88874338,0.043475448,DB0137310028245_,3.135558904,1.017179972,female,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,calcium,DB01373
,55268,DB06637,10028245,241,5921,97,1922,0.082109129,0.806507538,0.630827231,1.037638505,0.181856119,DB0663710028245_,1.704539458,-0.215042034,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,55269,DB13961,10028245,43,9414,8,6406,0.000261076,3.657293825,1.698268002,9.012595122,0.001800675,DB1396110028245_,6.319593507,1.296723482,female,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,55270,DB00264,10028372,244,29363,200,24692,0.811066036,1.025927849,0.846809428,1.244085674,0.898374276,DB0026410028372_,0.107168509,0.025597422,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,55271,DB00722,10028372,186,25217,163,25869,0.147175718,1.170603309,0.942774722,1.454655043,0.279992311,DB0072210028372_,1.272993138,0.157519264,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,55272,DB00758,10028372,80,8220,84,9990,0.386080301,1.157444308,0.840133737,1.593576692,0.556213797,DB0075810028372_,0.586602532,0.146214392,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,clopidogrel,DB00758
,55273,DB01062,10028372,71,4415,28,1717,1,0.986144962,0.626052799,1.592467729,1,DB0106210028372_,0,-0.013951915,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,oxybutynin,DB01062
,55274,DB13961,10028372,106,9351,66,6348,0.639415286,1.09029895,0.792929401,1.508464329,0.776485599,DB1396110028372_,0.252977182,0.086451924,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,55275,DB01373,10033775,310,22410,62,7319,0.000265476,1.63289113,1.237998718,2.183934285,0.00182623,DB0137310033775_,6.305501565,0.490352143,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,calcium,DB01373
,55276,DB06637,10033775,143,6019,34,1985,0.094049349,1.386975849,0.944989142,2.087411446,0.201844225,DB0663710033775_,1.600259041,0.327125729,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,55277,DB13961,10033775,130,9327,45,6369,5.08078008415084e-05,1.972609532,1.393190365,2.838431121,0.000448149,DB1396110033775_,7.710385522,0.679357302,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,55278,DB01373,10044565,235,22485,54,7327,0.01947184,1.418060378,1.049682755,1.945714195,0.060545019,DB0137310044565_,2.804368075,0.349290007,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,calcium,DB01373
,55279,DB06637,10044565,89,6073,30,1989,0.914725764,0.971630516,0.633717355,1.52768266,0.961865977,DB0663710044565_,0.038880155,-0.028779674,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,55280,DB00641,10048393,72,14052,28,12447,0.000122346,2.277573762,1.452275021,3.663932295,0.000948075,DB0064110048393_,6.961077207,0.823110737,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,55281,DB00722,10048393,135,25268,47,25985,9.69751651753844e-12,2.953878994,2.103931179,4.211742131,3.71573209422009e-10,DB0072210048393_,21.71327521,1.08311922,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,55283,DB01062,10048393,130,4356,33,1712,0.026826373,1.548201064,1.044799822,2.352677867,0.077619154,DB0106210048393_,2.555941049,0.437093653,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,55284,DB06637,10048393,428,5734,132,1887,0.542787629,1.067039417,0.869492296,1.316148263,0.698014408,DB0663710048393_,0.359515535,0.064887913,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,55285,DB13961,10048393,66,9391,18,6396,0.000309436,2.497140821,1.463333367,4.474029598,0.002070392,DB1396110048393_,6.180017196,0.915146406,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,55286,DB00108,10048592,72,10122,26,3269,0.637177163,0.894344604,0.562940766,1.462107718,0.774499498,DB0010810048592_,0.255538267,-0.111664115,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,natalizumab,DB00108
,55287,DB00264,10048592,57,29550,24,24868,0.003595919,1.998638019,1.220205865,3.368587502,0.015655276,DB0026410048592_,4.156947321,0.692465958,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,55289,DB00722,10048592,31,25372,28,26004,0.696457364,1.134717544,0.658355318,1.963924787,0.817376903,DB0072210048592_,0.201654965,0.12638376,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,55292,DB01373,10048592,52,22668,9,7372,0.099621508,1.878902189,0.916941349,4.339283751,0.210181912,DB0137310048592_,1.559781876,0.630687664,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,55294,DB08908,10048592,52,10621,15,3264,1,1.065339495,0.589729075,2.040360746,1,DB0890810048592_,0,0.063293523,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,dimethyl fumarate,DB08908
,55296,DB00641,10052904,85,14039,57,12418,0.109706599,1.319028828,0.931190198,1.880416638,0.225619118,DB0064110052904_,1.488907019,0.27689573,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,55297,DB00722,10052904,137,25266,87,25945,0.000472097,1.617005692,1.226350066,2.141810402,0.002944378,DB0072210052904_,5.82785774,0.480576101,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,55298,DB00758,10052904,36,8264,33,10041,0.275595272,1.325456265,0.802511681,2.195752871,0.43887203,DB0075810052904_,0.823547412,0.281756751,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,clopidogrel,DB00758
,55300,DB06637,10052904,70,6092,34,1985,0.066373784,0.670877334,0.437750878,1.04592799,0.154834077,DB0663710052904_,1.865401205,-0.399168969,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,dalfampridine,DB06637
,55302,DB00264,10061224,71,29536,42,24850,0.072782954,1.42226372,0.957398581,2.136313526,0.166175891,DB0026410061224_,1.79470847,0.352249772,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,55303,DB00641,10061224,43,14081,23,12452,0.063180743,1.653243309,0.973800296,2.875719942,0.14927022,DB0064110061224_,1.901997059,0.502739,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,55304,DB00722,10061224,76,25327,38,25994,0.000229368,2.052630808,1.372488839,3.11611481,0.001616985,DB0072210061224_,6.427192182,0.719122292,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,55307,DB01373,10061224,73,22647,31,7350,0.210059422,0.764261599,0.495230043,1.205014256,0.36124256,DB0137310061224_,1.018205634,-0.268845141,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,55309,DB13961,10061224,37,9420,18,6396,0.272597266,1.395653813,0.773915199,2.606582339,0.435544773,DB1396110061224_,0.831157679,0.333362989,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,55310,DB01088,10035664,103,1326,25,412,0.330398679,1.279943306,0.807256118,2.09823962,0.499096536,DB0108810035664_,0.694955744,0.246815785,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,iloprost,DB01088
,55315,DB00374,10003445,194,17522,71,5653,0.38804572,0.881553871,0.667204594,1.175913465,0.558047899,DB0037410003445_,0.583310479,-0.126069166,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,55321,DB00497,10019196,43,19224,28,16347,0.285556037,1.30587289,0.792466713,2.183873784,0.450165857,DB0049710019196_,0.798139192,0.266871698,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,55328,DB00268,10047700,98,2877,23,1522,0.000287787,2.253749393,1.412700726,3.736305601,0.001949862,DB0026810047700_,6.239996875,0.812595226,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ropinirole,DB00268
,55329,DB06616,10047700,105,856,48,755,0.000241577,1.928696554,1.337757586,2.813606257,0.001685649,DB0661610047700_,6.385604689,0.656844414,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,bosutinib,DB06616
,55332,DB01267,10013573,24,2828,37,3678,0.604116615,0.843632363,0.481622731,1.452092495,0.747555739,DB0126710013573_,0.290946409,-0.170038468,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,paliperidone,DB01267
,55344,DB00811,10024384,26,2772,37,4119,0.897647137,1.044128316,0.605604949,1.776027411,0.956338178,DB0081110024384_,0.044643686,0.04318239,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,ribavirin,DB00811
,55360,DB00254,10028411,56,5879,24,3364,0.293241098,1.335107986,0.81229979,2.256821008,0.45885476,DB0025410028411_,0.779021546,0.289012177,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,doxycycline,DB00254
,55363,DB01164,10005557,35,6489,46,7890,0.822986411,0.925127623,0.577772058,1.469664569,0.906059659,DB0116410005557_,0.098650126,-0.07782358,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,calcium chloride,DB01164
,55367,DB09153,10040047,129,7670,157,5542,1.58068531472362e-05,0.593729318,0.465392192,0.756282861,0.000162085,DB0915310040047_,8.727389572,-0.521331758,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,55369,DB00115,10046571,523,17902,157,10315,1.03516408161127e-13,1.919376759,1.600061892,2.312919367,5.27823237345337e-12,DB0011510046571_,25.96742985,0.652000529,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,55370,DB00169,10046571,1036,37655,254,17921,2.72908712261004e-23,1.941158549,1.688627785,2.238276224,3.76556719253568e-21,DB0016910046571_,47.02838845,0.663284985,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,55372,DB00413,10046571,65,2134,22,1185,0.052988798,1.640424428,0.992039408,2.809508915,0.130615403,DB0041310046571_,2.035498126,0.494955006,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,pramipexole,DB00413
,55373,DB00455,10046571,220,9181,51,5067,2.46874431652218e-09,2.380622812,1.74486198,3.301844156,6.33700628513532e-08,DB0045510046571_,16.57427428,0.867362139,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,loratadine,DB00455
,55374,DB00641,10046571,317,13807,127,12348,2.67751883501588e-15,2.232145934,1.808603039,2.76839304,1.70408190262451e-13,DB0064110046571_,29.40057972,0.802963425,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,simvastatin,DB00641
,55375,DB00813,10046571,189,10383,36,10132,2.27480516021398e-25,5.122574202,3.567303978,7.54313793,3.57974665549766e-23,DB0081310046571_,51.68416511,1.633657087,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,fentanyl,DB00813
,55376,DB01373,10046571,533,22187,73,7308,1.28419781056851e-14,2.405046507,1.877217366,3.119764318,7.43505274246549e-13,DB0137310046571_,27.92740054,0.877569241,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,calcium,DB01373
,55379,DB08931,10013781,37,6540,15,2431,0.755947872,0.916892437,0.490162473,1.801691003,0.863147622,DB0893110013781_,0.147169546,-0.086765112,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,55380,DB06403,10047571,89,21382,20,6641,0.214708558,1.382086783,0.842955712,2.372751785,0.367076292,DB0640310047571_,1.002185573,0.323594519,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,ambrisentan,DB06403
,55381,DB08931,10047571,43,6534,14,2432,0.765703821,1.143187348,0.61216357,2.266722046,0.870844598,DB0893110047571_,0.138291736,0.13382028,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,riociguat,DB08931
,55391,DB00921,10020751,65,5780,46,4857,0.390131942,1.187377075,0.799818893,1.775384937,0.560025018,DB0092110020751_,0.579773821,0.171746736,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,buprenorphine,DB00921
,55392,DB00921,10052162,40,5805,10,4893,0.000279529,3.371128041,1.654652486,7.569293915,0.001905945,DB0092110052162_,6.262777377,1.215247419,female,10052162,Application site discharge,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,55393,DB00005,10002515,81,128001,12,42407,0.005670863,2.236128555,1.212729081,4.506467911,0.022620629,DB0000510002515_,3.788892981,0.804746047,NA,10002515,Animal bite,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,55399,DB00065,10019211,203,9261,76,4881,0.010872063,1.407743735,1.073812609,1.861617441,0.03805642,DB0006510019211_,3.268685473,0.341988235,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,infliximab,DB00065
,55406,DB00512,10013573,48,4689,43,5055,0.400339063,1.203385201,0.779040779,1.864033593,0.570193261,DB0051210013573_,0.561779921,0.185138586,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,vancomycin,DB00512
,55407,DB00512,10038695,122,4615,164,4934,0.062599849,0.795342638,0.621741579,1.015192369,0.148297692,DB0051210038695_,1.908533595,-0.228982266,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vancomycin,DB00512
,55412,DB00563,10021425,66,46580,12,15336,0.065031919,1.810720889,0.970144373,3.681865386,0.152494301,DB0056310021425_,1.880628055,0.593725047,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,methotrexate,DB00563
,55415,DB00005,10029354,35,128047,30,42389,0.000241888,0.386218494,0.230325021,0.651320525,0.001687152,DB0000510029354_,6.384713172,-0.951352022,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,etanercept,DB00005
,55416,DB00563,10029354,212,46434,305,15043,9.85492264565925e-62,0.225209231,0.187901416,0.269479192,8.63455472470511e-59,DB0056310029354_,133.6967483,-1.490725394,male,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,methotrexate,DB00563
,55419,DB05259,10035664,99,11171,22,2706,0.817755182,1.090032179,0.679966046,1.821323315,0.902645402,DB0525910035664_,0.102425491,0.086207218,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,glatiramer,DB05259
,55420,DB00794,10013709,46,790,38,571,0.57057525,0.875033744,0.548956189,1.401828341,0.721071708,DB0079410013709_,0.32701669,-0.133492829,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,primidone,DB00794
,55421,DB00230,10022004,105,19569,31,8620,0.050158105,1.491993768,0.99028889,2.307054541,0.125320566,DB0023010022004_,2.0768803,0.400113325,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,55425,DB01164,10037423,34,6490,38,7898,0.723423444,1.088842307,0.664084343,1.7788181,0.837386203,DB0116410037423_,0.177469901,0.085115028,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium chloride,DB01164
,55426,DB00590,10011906,22,754,102,1850,0.005865399,0.529311002,0.315333554,0.853096651,0.02325545,DB0059010011906_,3.761215781,-0.636179115,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,doxazosin,DB00590
,55427,DB00590,10016173,23,753,65,1887,0.718844518,0.886771063,0.521847584,1.458855172,0.833914209,DB0059010016173_,0.181624748,-0.120168432,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,doxazosin,DB00590
,55428,DB00658,10016173,35,1268,29,1367,0.313516797,1.300993593,0.767537833,2.220543301,0.481029265,DB0065810016173_,0.731827169,0.263128275,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sevelamer,DB00658
,55429,DB00904,10016173,587,22482,316,14140,0.029169652,1.168284606,1.015555627,1.3460319,0.082864497,DB0090410016173_,2.490548577,0.155536524,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,55431,DB00480,10039117,142,67286,186,67476,0.017368797,0.765600377,0.610824465,0.957892267,0.055341393,DB0048010039117_,2.894234131,-0.267094947,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,55434,DB00682,10039117,37,19422,49,16315,0.03929248,0.634321645,0.402182216,0.992749891,0.104228765,DB0068210039117_,2.261167133,-0.455199126,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,55435,DB00695,10039117,64,27985,64,20464,0.08834969,0.731263348,0.508694422,1.051186431,0.192503967,DB0069510039117_,1.64763852,-0.312981627,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,55436,DB00787,10039117,30,16970,50,17198,0.033154336,0.608073433,0.373106181,0.975622649,0.091631536,DB0078710039117_,2.389979787,-0.497459626,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,55437,DB00904,10039117,42,23027,33,14423,0.343331945,0.797189797,0.493052892,1.298785577,0.512594369,DB0090410039117_,0.66827045,-0.226662489,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,55438,DB00480,10037016,112,67316,112,67550,1,1.003476211,0.765123125,1.31608776,1,DB0048010037016_,0,0.003470183,NA,10037016,Protein total increased,10022891,Investigations,Inv,lenalidomide,DB00480
,55439,DB00480,10073133,184,67244,253,67409,0.001106257,0.729061773,0.599456365,0.885303262,0.005983122,DB0048010073133_,5.118812822,-0.315996814,NA,10073133,Plasma cell myeloma recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,55446,DB00051,10037087,436,25295,143,11277,0.001462169,1.359317835,1.121261983,1.65583935,0.007531475,DB0005110037087_,4.888664434,0.306982982,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,55463,DB00706,10011906,41,1034,1049,14876,0.000179375,0.562323397,0.398606076,0.773786632,0.001315164,DB0070610011906_,6.633793614,-0.575678154,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,55465,DB01142,10011906,97,1643,49,735,0.519285203,0.885625071,0.614487807,1.290031336,0.678484481,DB0114210011906_,0.387893672,-0.121461589,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,doxepin,DB01142
,55505,DB00230,10041349,570,19104,209,8442,0.022167249,1.205148053,1.024520445,1.421979387,0.067011631,DB0023010041349_,2.702889072,0.186602425,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,55548,DB00443,10036590,30,2116,50,1140,1.24422991245528e-06,0.323368258,0.19732726,0.521825879,1.73960549196207e-05,DB0044310036590_,10.95926711,-1.128963488,male,10036590,Premature baby,10036585,"Pregnancy, puerperium and perinatal conditions",Preg,betamethasone,DB00443
,55574,DB00443,10071404,45,2101,58,1132,1.50469910103588e-05,0.418141315,0.274878731,0.632561638,0.000155424,DB0044310071404_,8.769350479,-0.871935829,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,betamethasone,DB00443
,55582,DB00043,10011906,184,6229,134,2166,7.11135365973523e-10,0.47751266,0.378020219,0.604453726,2.03065650131603e-08,DB0004310011906_,17.7123216,-0.739164607,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,55589,DB00051,10046735,383,25348,105,11315,5.18153790189247e-06,1.628227739,1.307183821,2.042797507,6.10884609783555e-05,DB0005110046735_,9.703187564,0.487492147,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,55590,DB00051,10055798,64,25667,40,11380,0.089457271,0.709391543,0.470254396,1.081670864,0.194409622,DB0005110055798_,1.637787894,-0.343347658,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,adalimumab,DB00051
,55593,DB00584,10037844,53,2028,42,1832,0.603303267,1.139907423,0.742070393,1.760848051,0.746988853,DB0058410037844_,0.291705016,0.130947051,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,enalapril,DB00584
,55600,DB00331,10001760,287,24659,55,20697,1.31348138844014e-30,4.37956928,3.270264283,5.96041753,3.05529719426097e-28,DB0033110001760_,63.35550573,1.476950382,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,55601,DB00341,10001760,158,11247,16,5052,1.25827866765116e-11,4.435834182,2.644286403,7.960061069,4.72483639703011e-10,DB0034110001760_,21.47301799,1.489715689,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,cetirizine,DB00341
,55602,DB00331,10022093,143,24803,42,20710,1.605890633526e-10,2.84271753,2.00174708,4.114104039,5.06732716713456e-09,DB0033110022093_,19.10045234,1.044760472,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,55603,DB00331,10022095,92,24854,41,20711,0.000643554,1.869810433,1.280171673,2.773234601,0.003820192,DB0033110022095_,5.567454667,0.625837053,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,55607,DB00331,10053425,94,24852,27,20725,1.85520736449253e-07,2.903149305,1.874479678,4.637047459,3.17371464859656e-06,DB0033110053425_,12.66060784,1.065796115,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,55608,DB00341,10053425,77,11328,23,5045,0.102880049,1.490959564,0.924273507,2.492730915,0.215311286,DB0034110053425_,1.535670457,0.399419915,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,55609,DB00451,10053425,194,47077,18,15401,2.90454318273135e-09,3.525950593,2.171789704,6.077061405,7.3621906999126e-08,DB0045110053425_,16.42432321,1.260150072,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,55611,DB00222,10053762,80,3126,64,3064,0.238814466,1.2251667,0.867400538,1.736441011,0.396540634,DB0022210053762_,0.924976761,0.203076917,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,glimepiride,DB00222
,55612,DB00327,10053762,161,5977,129,4133,0.226111815,0.863030326,0.677921826,1.100419527,0.381020551,DB0032710053762_,0.964901966,-0.147305448,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,hydromorphone,DB00327
,55618,DB00563,10017918,85,46561,12,15336,0.003166301,2.333166258,1.268026819,4.693293355,0.014140893,DB0056310017918_,4.258684483,0.847226254,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,methotrexate,DB00563
,55621,DB00181,10061818,35,9821,32,5839,0.099023674,0.650325253,0.390561642,1.086201007,0.209382775,DB0018110061818_,1.563591244,-0.430282652,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,55629,DB00973,10019211,157,3694,76,2945,0.000359618,1.646808655,1.238824812,2.204890819,0.002346491,DB0097310019211_,6.054834101,0.498839266,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ezetimibe,DB00973
,55630,DB00973,10028411,128,3723,99,2922,0.945842829,1.014755536,0.770853626,1.339001967,0.984398597,DB0097310028411_,0.015724386,0.014647732,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ezetimibe,DB00973
,55633,DB00811,10012735,141,2657,159,3997,0.016000333,1.333948177,1.04995806,1.693445138,0.051835298,DB0081110012735_,2.959683941,0.288143099,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ribavirin,DB00811
,55672,DB00230,10041466,159,19515,43,8608,0.003534565,1.631006114,1.156811494,2.343194932,0.01543931,DB0023010041466_,4.170838396,0.489197072,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,55674,DB00273,10041466,42,8439,8,2185,0.487656463,1.359271198,0.629225567,3.357180056,0.651422988,DB0027310041466_,0.428596096,0.306948672,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,55681,DB00641,10041466,43,14081,30,12445,0.348652755,1.26678872,0.775950705,2.092787428,0.518169042,DB0064110041466_,0.657453754,0.236485131,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,55683,DB00999,10041466,43,21387,27,12212,0.710090762,0.909376567,0.548941852,1.531246182,0.827117597,DB0099910041466_,0.189808397,-0.094996005,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,55687,DB08932,10041466,43,19400,9,6588,0.204595139,1.622385554,0.779586679,3.787036521,0.354606391,DB0893210041466_,1.036746862,0.48389763,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,55689,DB11089,10041466,42,10133,23,8384,0.133673521,1.510860436,0.887246602,2.634276677,0.260876007,DB1108910041466_,1.343710054,0.412679314,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,docusate,DB11089
,55690,DB00158,10044390,52,16763,25,8079,1,1.002465064,0.610426809,1.687142096,1,DB0015810044390_,0,0.002462031,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,55699,DB00904,10044390,66,23003,28,14428,0.089563817,1.478437849,0.936388545,2.390906524,0.194520548,DB0090410044390_,1.637217478,0.390986023,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,55704,DB08932,10044390,48,19395,14,6583,0.769924189,1.163707124,0.630586322,2.287118287,0.873962496,DB0893210044390_,0.134717815,0.151610706,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,55741,DB00563,10005724,48,46598,7,15341,0.041287755,2.25733434,1.015323664,5.914623236,0.108302842,DB0056310005724_,2.222823884,0.814184622,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,methotrexate,DB00563
,55742,DB00635,10005724,115,32938,44,23750,0.000267377,1.884537528,1.320056576,2.733018099,0.001837148,DB0063510005724_,6.299540964,0.633682448,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,prednisone,DB00635
,55745,DB00635,10005802,45,33008,29,23765,0.723882955,1.117235922,0.685098105,1.848489056,0.837715468,DB0063510005802_,0.177076773,0.110857708,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,prednisone,DB00635
,55751,DB00563,10024264,83,46563,64,15284,6.95682340201818e-07,0.425694879,0.303387615,0.599682464,1.03986410646601e-05,DB0056310024264_,11.47383543,-0.854032436,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,55764,DB00046,10003549,120,5339,139,4553,0.016344493,0.73624204,0.569926438,0.949950664,0.05269087,DB0004610003549_,2.943313079,-0.306196355,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,55765,DB00047,10003549,187,9098,230,8288,0.002878209,0.74067443,0.60591675,0.904417687,0.013068037,DB0004710003549_,4.337585926,-0.300194116,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,55771,DB00682,10003997,54,19405,32,16332,0.129192749,1.420248881,0.900234617,2.274130016,0.254464699,DB0068210003997_,1.368593159,0.350832125,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,warfarin,DB00682
,55772,DB00374,10038428,91,17625,28,5696,0.914869388,1.050292323,0.680263019,1.668701594,0.961903265,DB0037410038428_,0.03884139,0.049068528,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,treprostinil,DB00374
,55773,DB00682,10038428,105,19354,47,16317,0.000225331,1.883421568,1.322246387,2.718299627,0.001593016,DB0068210038428_,6.442126177,0.633090106,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,warfarin,DB00682
,55775,DB00115,10005555,45,18380,20,10452,0.438438431,1.279499953,0.739701707,2.288712757,0.60684838,DB0011510005555_,0.499476304,0.24646934,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,55778,DB00169,10005555,75,38616,43,18132,0.322969695,0.818997737,0.555359952,1.2213228,0.491398881,DB0016910005555_,0.710499096,-0.199673958,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,55780,DB00264,10005555,74,29533,63,24829,1,0.98751146,0.695820035,1.405171587,1,DB0026410005555_,0,-0.012567177,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,metoprolol,DB00264
,55781,DB00695,10005555,88,27961,51,20477,0.197537239,1.263641369,0.884618226,1.821825782,0.346030151,DB0069510005555_,1.061229367,0.233997529,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,furosemide,DB00695
,55783,DB00761,10005555,53,15254,27,8598,0.727221901,1.106443104,0.683045354,1.831033188,0.840572004,DB0076110005555_,0.173672662,0.10115046,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,55786,DB01261,10005555,43,3738,39,3264,0.911528302,0.962743878,0.607809908,1.529088221,0.960287291,DB0126110005555_,0.040522778,-0.037967865,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,sitagliptin,DB01261
,55788,DB00046,10010305,52,5407,50,4642,0.618071515,0.892868151,0.592565898,1.346496252,0.759017463,DB0004610010305_,0.275730494,-0.113316356,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,insulin lispro,DB00046
,55789,DB00047,10010305,102,9183,94,8424,1,0.995419434,0.743524694,1.333898241,1,DB0004710010305_,0,-0.004591089,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,insulin glargine,DB00047
,55790,DB00115,10010305,189,18236,164,10308,7.38441387215258e-05,0.651402158,0.524886636,0.809117359,0.000614433,DB0011510010305_,7.394811007,-0.428628074,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,55792,DB00126,10010305,112,10059,69,5876,0.756804061,0.948195528,0.694982415,1.30148835,0.863898474,DB0012610010305_,0.146300024,-0.053194545,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ascorbic acid,DB00126
,55793,DB00177,10010305,44,4756,27,2823,0.902258669,0.9672728,0.584342983,1.628421273,0.957195726,DB0017710010305_,0.043747388,-0.033274713,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,valsartan,DB00177
,55795,DB01261,10010305,35,3746,46,3257,0.07299156,0.661591401,0.412627591,1.05245399,0.166514768,DB0126110010305_,1.792671276,-0.413107133,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,sitagliptin,DB01261
,55796,DB00046,10012174,78,5381,70,4622,0.803726006,0.957098877,0.682464333,1.34444469,0.893803439,DB0004610012174_,0.112269395,-0.043848573,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,insulin lispro,DB00046
,55798,DB00177,10012174,63,4737,42,2808,0.611501053,0.889187064,0.590541388,1.350855137,0.753518596,DB0017710012174_,0.283001581,-0.117447645,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,valsartan,DB00177
,55799,DB00213,10012174,325,18570,230,13191,1,1.003740184,0.843835171,1.195491183,1,DB0021310012174_,0,0.003733207,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,55801,DB01261,10012174,63,3718,72,3231,0.117693571,0.760422512,0.531654908,1.08525947,0.237729618,DB0126110012174_,1.436621308,-0.273881064,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,sitagliptin,DB01261
,55805,DB00695,10020993,125,27924,94,20434,0.83744251,0.973090614,0.738212955,1.286336175,0.91621962,DB0069510020993_,0.087499183,-0.027278073,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,55807,DB00863,10020993,23,10650,30,5810,0.002159332,0.418267304,0.231818435,0.745519619,0.010362033,DB0086310020993_,4.569606872,-0.871634567,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,ranitidine,DB00863
,55812,DB00126,10041466,41,10130,13,5932,0.065161916,1.846786882,0.969174534,3.759301994,0.152722333,DB0012610041466_,1.879133823,0.613447309,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,55814,DB00213,10041466,44,18851,29,13392,0.812591833,1.077881181,0.659077908,1.787422678,0.899211734,DB0021310041466_,0.10623675,0.074997245,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,55815,DB00695,10041466,70,27979,31,20497,0.020092541,1.654203488,1.068845406,2.614042012,0.061980102,DB0069510041466_,2.780941873,0.503319617,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,55817,DB00761,10041466,38,15269,17,8608,0.483714985,1.260183631,0.693765565,2.382465491,0.647955274,DB0076110041466_,0.433933607,0.231257449,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,55821,DB00213,10006784,88,18807,26,13395,3.47955038772136e-05,2.41055979,1.54029187,3.893145527,0.000323237,DB0021310006784_,8.037123962,0.879858999,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,55823,DB00678,10006784,81,15518,41,10683,0.116655459,1.360045554,0.922220699,2.033282584,0.236101373,DB0067810006784_,1.443494021,0.307518195,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,losartan,DB00678
,55826,DB00451,10040880,45,47226,12,15407,0.644854106,1.223389759,0.636257031,2.541273995,0.780709787,DB0045110040880_,0.24755179,0.201625496,NA,10040880,Skin irritation,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,55831,DB00654,10053762,68,3748,45,2553,0.923181499,1.029311093,0.693478861,1.540616609,0.966449231,DB0065410053762_,0.03412651,0.028889736,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,latanoprost,DB00654
,55832,DB00678,10053762,380,15219,276,10448,0.494041157,0.945209606,0.805677779,1.11002655,0.656714464,DB0067810053762_,0.42050596,-0.056348571,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,55833,DB01062,10053762,108,4378,40,1705,0.853185842,1.051492559,0.721804422,1.558661537,0.92828569,DB0106210053762_,0.074415738,0.05021064,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,oxybutynin,DB01062
,55846,DB01164,10005750,43,6481,29,7907,0.0169691,1.808906768,1.102294954,3.007850439,0.054304837,DB0116410005750_,2.913141971,0.592722667,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,calcium chloride,DB01164
,55856,DB01261,10047899,58,3723,31,3272,0.024977896,1.644203391,1.042608959,2.63814847,0.073418396,DB0126110047899_,2.611580748,0.497256006,NA,10047899,Weight increased,10022891,Investigations,Inv,sitagliptin,DB01261
,55857,DB06655,10047899,58,3630,27,2092,0.427061186,1.237987016,0.768723864,2.040127609,0.595703791,DB0665510047899_,0.518011731,0.213486687,NA,10047899,Weight increased,10022891,Investigations,Inv,liraglutide,DB06655
,55859,DB01076,10061224,71,25676,43,25540,0.011076227,1.642391608,1.108608172,2.458639832,0.038602311,DB0107610061224_,3.254443121,0.496153477,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,55864,DB01275,10007559,93,3886,76,3273,0.876046728,1.030653564,0.75012543,1.419758364,0.946904013,DB0127510007559_,0.05455755,0.030193129,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,hydralazine,DB01275
,55868,DB00678,10013709,693,14906,420,10304,0.039629176,1.140547948,1.006237425,1.294027167,0.104915434,DB0067810013709_,2.254600643,0.131508803,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,55869,DB00905,10013709,385,2333,63,862,8.69899635328586e-10,2.257513167,1.704414906,3.030002863,2.44810620070791e-08,DB0090510013709_,17.525366,0.814263839,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,bimatoprost,DB00905
,55871,DB00678,10013774,63,15536,16,10708,0.000132927,2.713746071,1.547730866,5.036192221,0.001016406,DB0067810013774_,6.891482617,0.998329994,NA,10013774,Dry eye,10015919,Eye disorders,Eye,losartan,DB00678
,55875,DB00451,10014020,107,47164,9,15410,4.0785663284811e-06,3.88452067,1.97066791,8.728728853,4.93825267755879e-05,DB0045110014020_,9.915913905,1.356999596,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,levothyroxine,DB00451
,55879,DB00678,10015958,52,15547,20,10704,0.02994859,1.790039503,1.049816954,3.16756522,0.084599537,DB0067810015958_,2.469826489,0.582237689,NA,10015958,Eye pain,10015919,Eye disorders,Eye,losartan,DB00678
,55880,DB00905,10015958,76,2642,13,912,0.018543391,2.017786281,1.105638439,3.981459911,0.058216018,DB0090510015958_,2.843594739,0.70200101,NA,10015958,Eye pain,10015919,Eye disorders,Eye,bimatoprost,DB00905
,55884,DB00451,10018388,58,47213,26,15393,0.203884138,0.727308764,0.450424934,1.204091159,0.353653912,DB0045110018388_,1.039436493,-0.318404182,NA,10018388,Glossodynia,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,55887,DB00678,10023644,34,15565,25,10699,0.792451835,0.934833544,0.541217243,1.635478621,0.887531177,DB0067810023644_,0.119311629,-0.067386794,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,losartan,DB00678
,55888,DB00905,10023644,46,2672,7,918,0.039058491,2.257388841,1.00748807,5.947081361,0.103759912,DB0090510023644_,2.265675588,0.814208765,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,bimatoprost,DB00905
,55890,DB00451,10028810,725,46546,151,15268,1.3849970095108e-07,1.574864541,1.318537139,1.891219087,2.44326485872425e-06,DB0045110028810_,12.92217536,0.454169263,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,55891,DB00678,10028810,255,15344,105,10619,5.23999783657209e-06,1.680686805,1.332029047,2.13317676,6.16394464686942e-05,DB0067810028810_,9.694208528,0.519202522,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,losartan,DB00678
,55894,DB00451,10030041,104,47167,29,15390,0.482470787,1.170128571,0.76861275,1.833111662,0.646862772,DB0045110030041_,0.435621106,0.157113632,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,levothyroxine,DB00451
,55895,DB00678,10030041,40,15559,24,10700,0.702683717,1.14612967,0.673836221,1.988904206,0.821621064,DB0067810030041_,0.196475983,0.136390762,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,losartan,DB00678
,55896,DB00905,10030041,281,2437,16,909,7.07627796632378e-21,6.54901545,3.934162761,11.6845812,8.17582269647562e-19,DB0090510030041_,41.64793542,1.879314725,female,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,bimatoprost,DB00905
,55901,DB00451,10034960,67,47204,14,15405,0.154755842,1.561762066,0.868936416,3.010025019,0.290450361,DB0045110034960_,1.236322593,0.445814714,NA,10034960,Photophobia,10015919,Eye disorders,Eye,levothyroxine,DB00451
,55905,DB00905,10037087,46,2672,7,918,0.039058491,2.257388841,1.00748807,5.947081361,0.103759912,DB0090510037087_,2.265675588,0.814208765,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,bimatoprost,DB00905
,55907,DB00905,10047513,57,2661,16,909,0.587149184,1.216882983,0.685002146,2.282327832,0.734285674,DB0090510047513_,0.308857124,0.196292657,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,bimatoprost,DB00905
,55909,DB00678,10047571,114,15485,42,10682,0.000407482,1.872344222,1.302529735,2.737054803,0.002603469,DB0067810047571_,5.950910622,0.627191241,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,losartan,DB00678
,55910,DB00905,10047571,38,2680,13,912,1,0.994720109,0.515561094,2.044511718,1,DB0090510047571_,0,-0.005293879,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,bimatoprost,DB00905
,55915,DB00482,10030124,63,8196,21,3050,0.713322798,1.116385828,0.670589998,1.929979101,0.829852605,DB0048210030124_,0.186507178,0.110096528,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,55922,DB00879,10016256,42,1735,127,3585,0.03658878,0.683381739,0.467914654,0.980795444,0.098745939,DB0087910016256_,2.315204995,-0.38070166,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,emtricitabine,DB00879
,55926,DB00695,10023126,32,28017,30,20498,0.368281296,0.780413262,0.459087082,1.32993605,0.538002216,DB0069510023126_,0.6198926,-0.247931677,NA,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,furosemide,DB00695
,55930,DB14500,10047700,301,7508,63,4010,3.68731218578288e-13,2.551623984,1.933294,3.412712437,1.74947654879608e-11,DB1450010047700_,24.76911939,0.936730013,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,55937,DB00654,10002034,35,3781,27,2571,0.696853062,0.881473775,0.516955843,1.518204338,0.817604014,DB0065410002034_,0.20137715,-0.126160028,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,latanoprost,DB00654
,55938,DB00158,10010774,292,16523,105,7999,0.009453709,1.346309507,1.071714103,1.701934517,0.034032834,DB0015810010774_,3.380429528,0.297367151,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,55939,DB00169,10010774,908,37783,410,17765,0.511035534,1.041278597,0.92436232,1.174572873,0.671376684,DB0016910010774_,0.398424923,0.040449378,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,55940,DB00175,10010774,150,7981,130,5976,0.24657688,0.863986219,0.676856988,1.104027242,0.405668959,DB0017510010774_,0.902217824,-0.146198461,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,55941,DB00335,10010774,166,8300,76,5389,0.011607296,1.418123252,1.072154719,1.889995912,0.040104868,DB0033510010774_,3.216257559,0.349334344,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,55942,DB00484,10010774,30,2477,21,1759,1,1.014473286,0.559721806,1.870940441,1,DB0048410010774_,0,0.014369548,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,brimonidine,DB00484
,55943,DB00654,10010774,65,3751,46,2552,0.845844082,0.961347146,0.646608685,1.439601841,0.922512467,DB0065410010774_,0.080654389,-0.039419701,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,latanoprost,DB00654
,55945,DB00158,10028810,389,16426,104,8000,1.96399272241313e-08,1.821650189,1.46112246,2.287848872,4.11835250966327e-07,DB0015810028810_,14.70264244,0.599742788,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,folic acid,DB00158
,55946,DB00169,10028810,728,37963,229,17946,4.54943609890663e-08,1.502796309,1.29221218,1.752890686,8.85136401626653e-07,DB0016910028810_,13.93752408,0.407327579,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,55950,DB00654,10028810,47,3769,13,2585,0.002296257,2.479315613,1.316418019,5.005621689,0.010883903,DB0065410028810_,4.520470381,0.907982559,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,latanoprost,DB00654
,55951,DB01041,10028810,41,3004,21,3097,0.010152286,2.012589834,1.158961765,3.593741133,0.035995528,DB0104110028810_,3.324360572,0.699422367,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,thalidomide,DB01041
,55952,DB11089,10028810,142,10033,60,8347,6.5475114665729e-06,1.968858874,1.443994861,2.712808526,7.48755009349005e-05,DB1108910028810_,9.499683811,0.677454123,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,docusate,DB11089
,55954,DB00158,10029331,136,16679,112,7992,3.02131001813696e-05,0.581844783,0.449091806,0.755132242,0.000285717,DB0015810029331_,8.160507568,-0.541551563,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,55955,DB00335,10029331,94,8372,51,5414,0.347263305,1.19187119,0.837268954,1.713671111,0.516691308,DB0033510029331_,0.660309666,0.175524501,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,55957,DB00581,10029331,34,2079,19,2050,0.052631316,1.764268277,0.974516467,3.285733568,0.129965158,DB0058110029331_,2.040488877,0.567736031,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,lactulose,DB00581
,55958,DB00654,10029331,44,3772,25,2573,0.53807686,1.200497494,0.7167088,2.052355895,0.694101061,DB0065410029331_,0.365137708,0.182736049,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,latanoprost,DB00654
,55959,DB01373,10029331,330,22390,176,7205,2.13647415301797e-07,0.603378094,0.499970838,0.73012976,3.59766107002395e-06,DB0137310029331_,12.53522663,-0.505211258,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,calcium,DB01373
,55976,DB00722,10005555,67,25336,56,25976,0.279052918,1.226643697,0.846941179,1.782467321,0.442916219,DB0072210005555_,0.814374648,0.204281738,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,lisinopril,DB00722
,55978,DB01067,10005555,57,4304,45,4778,0.090828716,1.40610299,0.932344883,2.131881785,0.196561238,DB0106710005555_,1.626781253,0.340822041,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,glipizide,DB01067
,55986,DB01067,10018484,36,4325,42,4781,0.821120873,0.947505287,0.588623938,1.51820138,0.904725148,DB0106710018484_,0.100124085,-0.053922762,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,glipizide,DB01067
,55992,DB00635,10003119,35,33018,39,23755,0.060158884,0.645684346,0.39701895,1.046471288,0.143758922,DB0063510003119_,1.939617538,-0.437444524,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,prednisone,DB00635
,55998,DB00959,10020772,167,7911,97,4905,0.654416064,1.067465004,0.824013911,1.389113623,0.788220054,DB0095910020772_,0.237977972,0.065286683,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,methylprednisolone,DB00959
,56003,DB00635,10046555,51,33002,54,23740,0.048134584,0.679403838,0.453955722,1.015525413,0.121586835,DB0063510046555_,2.107126581,-0.386539573,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,56005,DB00959,10048393,101,7977,24,4978,4.73723319629036e-06,2.626010058,1.666760644,4.29279538,5.64324380532482e-05,DB0095910048393_,9.782466422,0.965465606,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,56007,DB00635,10067585,31,33022,26,23768,0.592496628,0.858183594,0.492950928,1.505216772,0.738653664,DB0063510067585_,0.302926122,-0.152937224,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,56009,DB00169,10003662,40,38651,43,18132,0.000212464,0.436393197,0.276366919,0.687641533,0.00151488,DB0016910003662_,6.492419011,-0.829211613,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,56011,DB00451,10003662,51,47220,36,15383,0.000647313,0.461509158,0.295237243,0.728252425,0.00383788,DB0045110003662_,5.562835249,-0.77325338,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,56012,DB00682,10003662,69,19390,49,16315,0.405075712,1.1848408,0.809213213,1.746421394,0.574774972,DB0068210003662_,0.553776668,0.169608419,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,warfarin,DB00682
,56016,DB01118,10003662,25,3038,30,4679,0.406356752,1.28340553,0.722246787,2.262285895,0.575939566,DB0111810003662_,0.551752544,0.249517116,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,amiodarone,DB01118
,56052,DB00820,10056819,64,11851,23,5793,0.251992471,1.360199056,0.831920175,2.298092471,0.412083373,DB0082010056819_,0.886529589,0.307631054,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,56058,DB08901,10061309,27,480,43,537,0.1744382,0.702697958,0.410696607,1.183801637,0.316687027,DB0890110061309_,1.149841288,-0.352828127,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ponatinib,DB08901
,56061,DB00203,10039163,345,13533,124,8814,6.02742615162145e-09,1.812027474,1.468939125,2.247299125,1.42537918484363e-07,DB0020310039163_,15.76365778,0.59444637,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,sildenafil,DB00203
,56068,DB00820,10013911,42,11873,28,5788,0.203604539,0.731227403,0.442213342,1.226340165,0.353409193,DB0082010013911_,1.040128707,-0.313030783,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,56069,DB00381,10019708,30,29330,20,22867,0.669534268,1.169456119,0.642367181,2.173315035,0.799378086,DB0038110019708_,0.223921247,0.156538785,NA,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,amlodipine,DB00381
,56075,DB00381,10027141,40,29320,36,22851,0.56383059,0.865966039,0.537890372,1.398654284,0.715713867,DB0038110027141_,0.334474818,-0.143909587,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,56078,DB00788,10028334,155,9201,68,4993,0.157432266,1.236970068,0.922217079,1.673787265,0.294104734,DB0078810028334_,1.223819338,0.212664896,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,56079,DB00820,10028334,206,11709,77,5739,0.047671126,1.311292224,1.002490667,1.729993633,0.120716334,DB0082010028334_,2.11431183,0.271013081,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,56080,DB00788,10053762,207,9149,94,4967,0.160769819,1.195492551,0.930029679,1.546161244,0.298561163,DB0078810053762_,1.208780467,0.178558277,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,56081,DB00820,10053762,235,11680,155,5661,0.003797994,0.734816832,0.595841278,0.9082761,0.016357575,DB0082010053762_,4.113064164,-0.308134019,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tadalafil,DB00820
,56085,DB00381,10072268,32,29328,38,22849,0.091012569,0.656086725,0.396694203,1.078825717,0.196869964,DB0038110072268_,1.625211848,-0.421462296,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,amlodipine,DB00381
,56088,DB00993,10002034,60,3189,34,1585,0.580682473,0.877126182,0.563898643,1.384236213,0.729129807,DB0099310002034_,0.315903502,-0.131104418,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,azathioprine,DB00993
,56089,DB00993,10013573,81,3168,18,1601,0.001111341,2.273820945,1.346413873,4.042273346,0.006006293,DB0099310013573_,5.114947545,0.821461652,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,azathioprine,DB00993
,56094,DB00993,10033661,48,3201,29,1590,0.396610439,0.822206085,0.505828106,1.357821587,0.566170933,DB0099310033661_,0.568859244,-0.195764204,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,azathioprine,DB00993
,56098,DB00820,10043071,98,11817,35,5781,0.115590121,1.369788616,0.9211751,2.079669536,0.234562365,DB0082010043071_,1.450033776,0.314656433,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,tadalafil,DB00820
,56101,DB08932,10043071,159,19284,29,6568,0.001315547,1.867449331,1.249750551,2.88127233,0.006896518,DB0893210043071_,4.976738604,0.624573506,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,macitentan,DB08932
,56103,DB01088,10064911,70,1359,23,414,0.801601836,0.927182983,0.563322012,1.577121582,0.892668641,DB0108810064911_,0.11353983,-0.07560434,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iloprost,DB01088
,56104,DB00455,10020751,130,9271,40,5078,0.001176755,1.780055742,1.237984272,2.609281924,0.006300234,DB0045510020751_,5.067168543,0.576644679,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,loratadine,DB00455
,56107,DB00996,10003591,47,38906,32,22393,0.483886172,0.84537321,0.527988443,1.369427658,0.648148803,DB0099610003591_,0.433634975,-0.16797708,NA,10003591,Ataxia,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,56109,DB00080,10053762,34,606,52,861,0.821874469,0.929008314,0.577014939,1.47903068,0.905158712,DB0008010053762_,0.099644978,-0.073637591,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,daptomycin,DB00080
,56110,DB00448,10008190,34,5111,20,3104,1,1.032437766,0.5763461,1.896457372,1,DB0044810008190_,0,0.031922769,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,lansoprazole,DB00448
,56111,DB00813,10008190,52,10520,46,10122,0.686921758,1.087634951,0.716593431,1.655606027,0.811183971,DB0081310008190_,0.209260406,0.084005569,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,56112,DB00186,10001551,77,16824,60,9948,0.111350854,0.758857444,0.533924552,1.082934775,0.22808279,DB0018610001551_,1.478046602,-0.27594134,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,lorazepam,DB00186
,56116,DB00186,10003481,104,16797,48,9960,0.177907346,1.284746339,0.903324726,1.850147846,0.321218202,DB0018610003481_,1.135634629,0.250561297,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,lorazepam,DB00186
,56119,DB01060,10003481,31,8556,29,5052,0.081810002,0.631233783,0.367538079,1.086944856,0.181399914,DB0106010003481_,1.707051216,-0.460078989,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,amoxicillin,DB01060
,56121,DB00741,10003549,129,3965,92,3082,0.581764235,1.089926813,0.824040237,1.446280771,0.730052178,DB0074110003549_,0.314639271,0.08611055,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,56127,DB01104,10035669,42,15421,26,7260,0.297773467,0.760482699,0.45513454,1.29311193,0.463683387,DB0110410035669_,0.768553315,-0.273801917,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,sertraline,DB01104
,56128,DB00706,10006451,11,1064,98,15827,0.111626379,1.669571006,0.804513296,3.132804444,0.228503515,DB0070610006451_,1.476203687,0.512566711,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,tamsulosin,DB00706
,56132,DB09053,10015090,40,2245,54,3998,0.194863575,1.319051368,0.850931901,2.02971598,0.342848762,DB0905310015090_,1.070465856,0.276912818,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibrutinib,DB09053
,56136,DB00559,10001551,89,9570,56,3250,0.000508768,0.539776617,0.381111357,0.770008589,0.003132573,DB0055910001551_,5.765900564,-0.616599898,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,bosentan,DB00559
,56137,DB08932,10001551,98,19345,45,6552,0.100805297,0.737605675,0.512562653,1.075760273,0.212075175,DB0893210001551_,1.550814467,-0.304345912,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,macitentan,DB08932
,56138,DB00559,10003481,85,9574,52,3254,0.00148665,0.555612124,0.387952609,0.802307437,0.007633641,DB0055910003481_,4.8751904,-0.587684847,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,bosentan,DB00559
,56139,DB08932,10003481,134,19309,54,6543,0.275191949,0.840904735,0.607929287,1.177287378,0.438495417,DB0893210003481_,0.82440592,-0.173276901,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,macitentan,DB08932
,56140,DB00559,10024690,75,9584,23,3283,0.72745481,1.117000491,0.690803464,1.871191088,0.840804242,DB0055910024690_,0.173396414,0.110646959,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,bosentan,DB00559
,56142,DB08932,10050584,173,19270,31,6566,0.000641197,1.901588734,1.290333923,2.887513894,0.003809216,DB0893210050584_,5.570331903,0.642689713,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,56143,DB00559,10061428,130,9529,37,3269,0.371389082,1.205316095,0.828869557,1.79103246,0.541008758,DB0055910061428_,0.614319811,0.186741852,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,bosentan,DB00559
,56144,DB08932,10061428,714,18729,180,6417,0.000230527,1.359029125,1.149539693,1.613419552,0.001622734,DB0893210061428_,6.423642944,0.306770566,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,macitentan,DB08932
,56145,DB06403,10037844,335,21136,99,6562,0.690814889,1.050530823,0.835633466,1.330623951,0.81351044,DB0640310037844_,0.206396518,0.049295582,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ambrisentan,DB06403
,56151,DB00734,10013710,99,3951,151,4751,0.071337751,0.788402769,0.603375374,1.026401772,0.163593856,DB0073410013710_,1.81036841,-0.237746191,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,56155,DB11089,10013710,86,10089,69,8338,0.871622117,1.030063845,0.740591836,1.437184155,0.943480712,DB1108910013710_,0.058179357,0.029620786,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,56166,DB06273,10028813,195,4900,30,1380,0.001667002,1.830396021,1.235239268,2.799014543,0.008376439,DB0627310028813_,4.782332449,0.604532349,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,tocilizumab,DB06273
,56167,DB06273,10047700,107,4988,15,1395,0.010341794,1.994742162,1.152221752,3.700536198,0.036561405,DB0627310047700_,3.308762113,0.6905148,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,tocilizumab,DB06273
,56170,DB00005,10008611,97,127985,25,42394,0.295326752,1.285206106,0.820952162,2.082883542,0.461267079,DB0000510008611_,0.773778056,0.250919099,NA,10008611,Cholecystectomy,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,56175,DB01068,10069327,79,13684,33,6807,0.422758605,1.190817805,0.783019754,1.848040486,0.591672963,DB0106810069327_,0.524801223,0.174640302,NA,10069327,Product quality issue,10077536,Product issues,Prod,clonazepam,DB01068
,56176,DB00005,10034568,55,128027,15,42404,0.581316398,1.214434995,0.676389105,2.314886724,0.729664368,DB0000510034568_,0.315170621,0.194278944,NA,10034568,Peripheral coldness,10047065,Vascular disorders,Vasc,etanercept,DB00005
,56198,DB00103,10028813,19,375,54,604,0.044273213,0.567001279,0.312246131,0.990008134,0.114146287,DB0010310028813_,2.17027443,-0.56739372,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,agalsidase beta,DB00103
,56199,DB00887,10028813,188,2153,62,1753,2.57553728006876e-10,2.468308494,1.829480934,3.368497693,7.89481019319036e-09,DB0088710028813_,18.65706023,0.903533096,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,bumetanide,DB00887
,56200,DB00343,10047700,317,8419,95,5000,1.40349215688187e-09,1.981640619,1.566428175,2.526192719,3.78173155752332e-08,DB0034310047700_,17.09049876,0.683925097,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,56201,DB00887,10047700,104,2237,38,1777,3.07237756630654e-05,2.173638251,1.47724065,3.258137115,0.000289713,DB0088710047700_,8.146620454,0.776402377,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,bumetanide,DB00887
,56203,DB00230,10006784,339,19335,172,8479,0.132876615,0.864329899,0.715994877,1.04643637,0.259783691,DB0023010006784_,1.347905953,-0.145800756,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,56204,DB00335,10006784,64,8402,17,5448,0.000560986,2.440951652,1.410576914,4.450836233,0.003394068,DB0033510006784_,5.685726088,0.892387985,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,56206,DB00497,10006784,78,19189,40,16335,0.009361151,1.659946837,1.119152206,2.496342653,0.033766688,DB0049710006784_,3.388280526,0.506785576,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,56207,DB01104,10006784,64,15399,19,7267,0.077619326,1.589574605,0.939414212,2.811888192,0.174311077,DB0110410006784_,1.746913779,0.463466436,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,56209,DB01104,10008531,114,15349,49,7237,0.614332728,1.096944112,0.777322894,1.568130588,0.755840897,DB0110410008531_,0.279924379,0.092528233,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,56211,DB00230,10016825,60,19614,20,8631,0.331076932,1.32007301,0.783874082,2.313810927,0.499790786,DB0023010016825_,0.693565697,0.277687046,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,pregabalin,DB00230
,56214,DB00335,10037087,172,8294,58,5407,8.36950636599973e-06,1.933181483,1.424726423,2.656015647,9.30397440601831e-05,DB0033510037087_,9.282483801,0.659167083,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,atenolol,DB00335
,56215,DB00422,10037087,47,3388,37,2912,0.741592475,1.091823842,0.692448653,1.732850917,0.851841572,DB0042210037087_,0.160354718,0.087849548,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,methylphenidate,DB00422
,56216,DB00422,10037660,50,3385,47,2902,0.682150237,0.912047333,0.598098549,1.392799978,0.807799382,DB0042210037660_,0.21344154,-0.09206339,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,56217,DB00669,10000081,84,6293,14,1083,1,1.03257517,0.579842647,1.976827268,1,DB0066910000081_,0,0.032055847,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,sumatriptan,DB00669
,56226,DB00316,10015150,516,64958,250,36703,0.049505318,1.166240999,1.000241359,1.362591724,0.1240747,DB0031610015150_,2.086871476,0.153785755,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,56227,DB00959,10015150,111,7967,58,4944,0.301543307,1.187567913,0.855055878,1.664383333,0.46783531,DB0095910015150_,0.759638947,0.171907445,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,methylprednisolone,DB00959
,56232,DB00959,10019211,440,7638,129,4873,7.92339811657048e-16,2.17597636,1.778184957,2.677826814,5.36078557256255e-14,DB0095910019211_,30.55708078,0.777477465,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,56233,DB00103,10025482,34,360,38,620,0.078733142,1.540211652,0.922584688,2.563009897,0.176195193,DB0010310025482_,1.736162846,0.431919843,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,agalsidase beta,DB00103
,56234,DB00959,10025482,208,7870,85,4917,0.000996257,1.528819713,1.17917241,1.99662091,0.005483533,DB0095910025482_,5.206005721,0.424496008,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,56235,DB00103,10046735,23,371,31,627,0.470955034,1.253596312,0.686811691,2.258746399,0.637208683,DB0010310046735_,0.450658075,0.22601647,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,agalsidase beta,DB00103
,56236,DB00959,10046735,218,7860,92,4910,0.001682033,1.480181673,1.151662941,1.914921532,0.008439062,DB0095910046735_,4.774884104,0.392164832,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,methylprednisolone,DB00959
,56245,DB00695,10047531,39,28010,17,20511,0.078730243,1.679900853,0.927987339,3.167950937,0.176195193,DB0069510047531_,1.736162846,0.518734776,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,furosemide,DB00695
,56248,DB00203,10016322,375,13503,159,8779,5.53319127847256e-06,1.533348249,1.2677698,1.861402665,6.46112540002893e-05,DB0020310016322_,9.647121952,0.427453742,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,56249,DB00374,10016322,514,17202,137,5587,0.041826538,1.218530075,1.004765448,1.485910823,0.109388643,DB0037410016322_,2.212848208,0.197645276,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,56250,DB00374,10047700,1203,16513,256,5468,8.0768817411223e-11,1.55609621,1.353630548,1.794000924,2.67381406253652e-09,DB0037410047700_,19.7397599,0.442180255,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,56252,DB00230,10005750,168,19506,63,8588,0.315234587,1.174049716,0.872878958,1.596273287,0.482823431,DB0023010005750_,0.72810426,0.160459068,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,pregabalin,DB00230
,56253,DB00668,10005750,87,10004,51,4252,0.075669489,0.725060783,0.506372499,1.047576083,0.170910635,DB0066810005750_,1.766614462,-0.321499789,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,epinephrine,DB00668
,56256,DB09153,10005750,64,7735,59,5640,0.20018872,0.790966143,0.545567502,1.148431906,0.349205416,DB0915310005750_,1.052094945,-0.234500115,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,sodium chloride,DB09153
,56258,DB00193,10016334,55,19265,17,8685,0.202275623,1.458533694,0.833321383,2.682199594,0.35168096,DB0019310016334_,1.045030879,0.377431612,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,56259,DB00230,10016334,68,19606,20,8631,0.131358892,1.496759083,0.897360435,2.603975348,0.25768852,DB0023010016334_,1.356003711,0.403302159,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,56260,DB00316,10016334,194,65280,76,36877,0.006312868,1.441989274,1.100208228,1.90626299,0.024664993,DB0031610016334_,3.702370348,0.3660236,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,56261,DB00341,10016334,47,11358,12,5056,0.090304627,1.74344719,0.909651515,3.61384491,0.195725179,DB0034110016334_,1.63104375,0.555864297,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,56266,DB00668,10025482,204,9887,51,4252,0.000408606,1.720180983,1.257196893,2.391386346,0.002609261,DB0066810025482_,5.948688075,0.542429508,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,56267,DB00737,10025482,111,2690,26,906,0.107696841,1.437716983,0.924195604,2.312556446,0.222683772,DB0073710025482_,1.502002576,0.363056427,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,meclizine,DB00737
,56269,DB00193,10033775,220,19100,64,8638,0.001554759,1.554591425,1.17043242,2.089642278,0.007919181,DB0019310033775_,4.838467488,0.441212762,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,56270,DB00341,10033775,129,11276,33,5035,0.003524009,1.745448773,1.181054837,2.646104621,0.015404977,DB0034110033775_,4.173064654,0.557011699,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,56271,DB00668,10033775,67,10024,17,4286,0.055733402,1.68508946,0.976860974,3.065391413,0.135593527,DB0066810033775_,1.99809364,0.521818654,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,epinephrine,DB00668
,56272,DB00737,10033775,46,2755,7,925,0.053838917,2.206112168,0.98465627,5.812584444,0.132214316,DB0073710033775_,2.023331063,0.791231766,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,meclizine,DB00737
,56274,DB09153,10033775,41,7758,23,5676,0.37469339,1.304187384,0.76342622,2.279655958,0.544536523,DB0915310033775_,0.607820262,0.265580152,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,56276,DB01432,10012735,210,1081,88,582,0.073267069,1.284635012,0.97592876,1.701195704,0.166954913,DB0143210012735_,1.790031486,0.250474641,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cholestyramine,DB01432
,56277,DB01432,10028813,76,1215,26,644,0.067858556,1.549028389,0.969419976,2.546593525,0.157476903,DB0143210028813_,1.848476477,0.437627889,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cholestyramine,DB01432
,56278,DB01592,10028813,399,5877,115,2952,9.63879171016803e-08,1.742657507,1.405658034,2.173992385,1.74788299483799e-06,DB0159210028813_,13.25710522,0.555411251,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,56280,DB00413,10033425,56,2143,25,1182,0.412658112,1.235468576,0.753674863,2.077865701,0.582098236,DB0041310033425_,0.541116056,0.211450312,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,pramipexole,DB00413
,56281,DB00572,10033425,64,2838,32,2094,0.076699728,1.475575252,0.946959399,2.340777416,0.17271073,DB0057210033425_,1.756137166,0.389047915,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,atropine,DB00572
,56283,DB01592,10033425,183,6093,46,3021,1.75197162536697e-05,1.972354331,1.416051658,2.796309892,0.000177664,DB0159210033425_,8.635615012,0.679227921,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,iron,DB01592
,56291,DB00213,10022000,204,18691,141,13280,0.826243062,1.027962338,0.824326217,1.284820879,0.908295473,DB0021310022000_,0.096185543,0.02757853,NA,10022000,Influenza,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,56292,DB00437,10022000,67,6854,103,11443,0.633108699,1.086002643,0.785039805,1.493829868,0.771786576,DB0043710022000_,0.259047223,0.082503655,NA,10022000,Influenza,10021881,Infections and infestations,Infec,allopurinol,DB00437
,56293,DB01261,10022000,31,3750,23,3280,0.586053167,1.178870624,0.663944382,2.121848816,0.733315171,DB0126110022000_,0.310179695,0.164556882,NA,10022000,Influenza,10021881,Infections and infestations,Infec,sitagliptin,DB01261
,56298,DB00186,10042609,45,16856,22,9986,0.527572555,1.211736038,0.712126185,2.120427734,0.685123619,DB0018610042609_,0.378155991,0.192054073,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,lorazepam,DB00186
,56299,DB00213,10042609,79,18816,43,13378,0.16806494,1.306227314,0.889276764,1.941792768,0.308243166,DB0021310042609_,1.176866307,0.267143069,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,pantoprazole,DB00213
,56300,DB00264,10042609,94,29513,50,24842,0.00920955,1.582436724,1.110789954,2.278046242,0.033334208,DB0026410042609_,3.401171136,0.458965889,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,metoprolol,DB00264
,56301,DB00316,10042609,268,65206,88,36865,5.26618016134118e-06,1.721775006,1.348000711,2.217237003,6.18911382171615e-05,DB0031610042609_,9.690133551,0.543355739,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,56303,DB00451,10042609,181,47090,43,15376,0.06213321,1.374410873,0.980418826,1.965105031,0.147424754,DB0045110042609_,1.914437376,0.318025183,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,levothyroxine,DB00451
,56311,DB00153,10047895,160,7263,88,3351,0.190154602,0.838900569,0.640556413,1.104564868,0.336738781,DB0015310047895_,1.08844778,-0.17566309,NA,10047895,Weight decreased,10022891,Investigations,Inv,ergocalciferol,DB00153
,56313,DB00476,10058920,79,17178,17,6160,0.06250474,1.666474769,0.976912191,3.005437153,0.148105749,DB0047610058920_,1.909828737,0.510710479,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,56314,DB01224,10058920,32,8076,21,5896,0.781170285,1.112502454,0.621292172,2.032150536,0.880828655,DB0122410058920_,0.126892162,0.106611941,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,56319,DB00773,10028533,44,2279,63,2764,0.433047895,0.847071234,0.56050598,1.270324104,0.601493549,DB0077310028533_,0.508339469,-0.165970486,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,etoposide,DB00773
,56320,DB00958,10028533,57,4537,20,2565,0.073167126,1.61115226,0.950741956,2.838090398,0.166799472,DB0095810028533_,1.790962954,0.476949612,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,carboplatin,DB00958
,56321,DB01181,10028533,37,536,39,881,0.068911818,1.558825929,0.953665866,2.544311982,0.159358391,DB0118110028533_,1.836599583,0.443932928,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ifosfamide,DB01181
,56323,DB00091,10008479,52,5458,19,2651,0.311871178,1.329303688,0.770926707,2.38584313,0.479305927,DB0009110008479_,0.735416206,0.284655263,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,56325,DB00227,10008479,32,2435,20,1783,0.672282998,1.171520456,0.647365511,2.169087822,0.801035624,DB0022710008479_,0.221849859,0.158302441,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,lovastatin,DB00227
,56327,DB01136,10008479,202,9682,193,10922,0.103667468,1.18066553,0.962523911,1.448585564,0.216514371,DB0113610008479_,1.530098356,0.166078288,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,56328,DB01373,10008479,254,22466,71,7310,0.27110479,1.164029026,0.89019391,1.538644573,0.433876608,DB0137310008479_,0.834995099,0.151887285,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,56329,DB09153,10008479,148,7651,98,5601,0.47386232,1.105583754,0.848636719,1.445553355,0.639721978,DB0915310008479_,0.446721607,0.10037348,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,56338,DB01240,10016173,259,5492,60,1516,0.264725802,1.191532818,0.891062159,1.614788068,0.426665708,DB0124010016173_,0.851754459,0.17524056,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,epoprostenol,DB01240
,56339,DB00682,10040753,240,19219,66,16298,1.7859934853068e-18,3.083460552,2.337231203,4.116421891,1.60221292700646e-16,DB0068210040753_,36.36997573,1.126052522,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,warfarin,DB00682
,56340,DB01240,10040753,149,5602,29,1547,0.096127516,1.418768641,0.943899484,2.20033729,0.20495715,DB0124010040753_,1.584954345,0.349789341,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,56346,DB00230,10013654,46,19628,34,8617,0.027846475,0.593974361,0.372766009,0.954935664,0.079876095,DB0023010013654_,2.527278658,-0.520919125,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,56347,DB09068,10022437,75,2320,20,966,0.085825362,1.561236832,0.936808927,2.7159062,0.188071667,DB0906810022437_,1.670932183,0.445478348,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,vortioxetine,DB09068
,56348,DB01076,10017577,420,25327,261,25322,1.50648477100717e-09,1.608853003,1.37388279,1.886778962,4.03032592426702e-08,DB0107610017577_,17.0268335,0.475521505,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,56349,DB01175,10017577,149,10575,52,4840,0.10767997,1.311366188,0.948499364,1.838138943,0.222683772,DB0117510017577_,1.502002576,0.271069485,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,56350,DB01409,10022437,71,5960,37,3929,0.277028161,1.264969552,0.836742422,1.940694647,0.440553299,DB0140910022437_,0.819723845,0.235048052,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,tiotropium,DB01409
,56351,DB01409,10033425,118,5913,41,3925,0.000296564,1.910304842,1.325287948,2.803220762,0.001998676,DB0140910033425_,6.215270136,0.647262832,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,tiotropium,DB01409
,56352,DB00108,10013573,158,10036,24,3271,0.000237749,2.14571303,1.387973041,3.454539799,0.001664465,DB0010810013573_,6.3982513,0.763471912,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,56353,DB00108,10013950,51,10143,21,3274,0.337973192,0.783919556,0.462408746,1.374299696,0.507070712,DB0010810013950_,0.679104813,-0.243448871,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,natalizumab,DB00108
,56361,DB00619,10028334,113,2786,95,2399,0.887387908,1.024243941,0.768320975,1.367855979,0.953324525,DB0061910028334_,0.047799903,0.023954722,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,imatinib,DB00619
,56362,DB00973,10028334,103,3748,63,2958,0.132382729,1.290265238,0.930300004,1.80155484,0.259116656,DB0097310028334_,1.35047691,0.254847808,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ezetimibe,DB00973
,56365,DB08895,10020937,319,27795,65,6581,0.296516501,1.16198479,0.886187709,1.54375393,0.462397213,DB0889510020937_,0.77133099,0.150129569,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,56366,DB08895,10028411,396,27718,85,6561,0.447959402,1.102762884,0.868954183,1.41313039,0.615714324,DB0889510028411_,0.484972183,0.097818743,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,56368,DB00635,10018651,34,33019,65,23729,1.96321959181171e-06,0.375912816,0.240622769,0.577907357,2.60359369176442e-05,DB0063510018651_,10.55603279,-0.978398035,NA,10018651,Graft versus host disease,10021428,Immune system disorders,Immun,prednisone,DB00635
,56370,DB00864,10018651,77,6792,118,8274,0.12824206,0.794938293,0.587522111,1.07039403,0.253155513,DB0086410018651_,1.373751302,-0.229490786,NA,10018651,Graft versus host disease,10021428,Immune system disorders,Immun,tacrolimus,DB00864
,56374,DB00864,10061428,54,6815,64,8328,0.926054051,1.031080463,0.703169629,1.506945623,0.968520073,DB0086410061428_,0.031986071,0.030607246,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,tacrolimus,DB00864
,56377,DB14513,10061428,154,7023,75,3489,0.943480343,1.020086832,0.766704023,1.367154242,0.982309309,DB1451310061428_,0.017849041,0.019887753,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,magnesium,DB14513
,56380,DB01234,10015916,60,31565,47,32841,0.147802593,1.328190567,0.891301642,1.989569939,0.280930736,DB0123410015916_,1.269647131,0.28381754,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,dexamethasone,DB01234
,56381,DB08910,10015916,37,16707,21,17467,0.025318899,1.842007826,1.049925184,3.313505726,0.074197785,DB0891010015916_,2.601020977,0.610856186,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,pomalidomide,DB08910
,56385,DB01281,10013968,149,8783,34,1764,0.48553443,0.880144418,0.600673094,1.322768646,0.649578688,DB0128110013968_,0.431431299,-0.127669273,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,abatacept,DB01281
,56393,DB06273,10000081,77,5018,23,1387,0.714871679,0.925356833,0.571917126,1.551286867,0.83101086,DB0627310000081_,0.185112415,-0.07757585,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,tocilizumab,DB06273
,56394,DB06273,10012735,134,4961,26,1384,0.098674158,1.437707872,0.934769366,2.290597064,0.208866841,DB0627310012735_,1.566058355,0.36305009,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,tocilizumab,DB06273
,56395,DB00008,10003239,38,1487,42,1634,1,0.994205326,0.620095801,1.589457625,1,DB0000810003239_,0,-0.005811529,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,peginterferon alfa-2a,DB00008
,56396,DB08934,10003239,82,4407,79,6125,0.024010998,1.442536778,1.0433862,1.995443961,0.071273754,DB0893410003239_,2.641227127,0.366403215,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sofosbuvir,DB08934
,56400,DB00811,10008479,49,2749,54,4102,0.129872393,1.353930496,0.897732555,2.037702272,0.255487471,DB0081110008479_,1.364581909,0.303011841,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,56401,DB08934,10008479,44,4445,54,6150,0.607437601,1.127344327,0.73810159,1.713713583,0.75037585,DB0893410008479_,0.287181065,0.119864714,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,56402,DB00008,10019211,87,1438,69,1607,0.039905031,1.408890285,1.006794588,1.977820179,0.105507593,DB0000810019211_,2.248972362,0.342802363,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,peginterferon alfa-2a,DB00008
,56410,DB00169,10047571,302,38389,88,18087,5.19504496439402e-05,1.616890545,1.270309318,2.075720233,0.000456237,DB0016910047571_,7.69249798,0.480504888,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,56411,DB06724,10047571,78,7851,13,3906,7.10246796112658e-05,2.984876959,1.645162268,5.86179026,0.00059417,DB0672410047571_,7.428344247,1.093558526,female,10047571,Visual impairment,10015919,Eye disorders,Eye,calcium carbonate,DB06724
,56412,DB11089,10047571,62,10113,24,8383,0.001069817,2.14128509,1.315952984,3.590862973,0.005820768,DB1108910047571_,5.146323127,0.761406158,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,docusate,DB11089
,56430,DB01109,10051055,54,4358,91,4179,0.001040538,0.569073855,0.397528258,0.807889913,0.005695064,DB0110910051055_,5.168155379,-0.563745055,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,heparin,DB01109
,56433,DB00437,10047571,37,6884,41,11505,0.07840428,1.50812462,0.939312224,2.414086893,0.175721051,DB0043710047571_,1.738857476,0.410866905,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,allopurinol,DB00437
,56435,DB00227,10010774,54,2413,39,1764,1,1.012207151,0.654907736,1.577111515,1,DB0022710010774_,0,0.012133244,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,lovastatin,DB00227
,56436,DB00927,10010774,195,7302,108,4908,0.122752682,1.213561141,0.951646698,1.554292869,0.245337356,DB0092710010774_,1.405121053,0.193559129,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,56441,DB00227,10037844,56,2411,37,1766,0.671998495,1.10861807,0.715439987,1.735719372,0.800901423,DB0022710037844_,0.222017406,0.103114258,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,lovastatin,DB00227
,56442,DB00927,10037844,237,7260,134,4882,0.118962805,1.189297887,0.955107445,1.485849405,0.239713085,DB0092710037844_,1.428312549,0.173363122,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,famotidine,DB00927
,56443,DB08901,10037844,52,455,26,554,0.00024178,2.433210298,1.465064868,4.129027026,0.001686622,DB0890110037844_,6.385027563,0.889211496,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ponatinib,DB08901
,56455,DB00987,10070863,43,2061,42,2886,0.120007427,1.433501058,0.911231075,2.256682822,0.241392402,DB0098710070863_,1.421331444,0.360119744,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,cytarabine,DB00987
,56473,DB08901,10016256,55,452,39,541,0.017301894,1.687097541,1.076893846,2.664288573,0.055158312,DB0890110016256_,2.897547823,0.523009621,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ponatinib,DB08901
,56477,DB00009,10008190,35,1316,34,1517,0.541817089,1.186566681,0.714238053,1.973179853,0.697150876,DB0000910008190_,0.360753427,0.171063995,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,alteplase,DB00009
,56479,DB00668,10021097,144,9947,91,4212,0.00394759,0.670085683,0.510469999,0.883339439,0.016896662,DB0066810021097_,4.080639181,-0.400349689,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,epinephrine,DB00668
,56482,DB00668,10066286,50,10041,17,4286,0.503853874,1.255399175,0.710794789,2.324733483,0.664963931,DB0066810066286_,0.408022478,0.22745359,NA,10066286,Stress cardiomyopathy,10007541,Cardiac disorders,Card,epinephrine,DB00668
,56484,DB00999,10014387,37,21393,36,12203,0.027626037,0.586304736,0.360176024,0.955130721,0.079416052,DB0099910014387_,2.533054765,-0.533915597,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,56485,DB00999,10028411,284,21146,111,12128,0.000607909,1.467410243,1.172856411,1.846487447,0.003638593,DB0099910028411_,5.61615812,0.383499108,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,56486,DB00999,10036653,55,21375,28,12211,0.649626032,1.122160276,0.69920471,1.838382149,0.784355546,DB0099910036653_,0.242892858,0.115255645,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,56488,DB00635,10012601,154,32899,109,23685,0.900518496,1.017150404,0.790217532,1.313017804,0.956698706,DB0063510012601_,0.044266769,0.017004996,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,56489,DB00688,10012601,36,6454,32,5346,0.807606962,0.931882428,0.561780695,1.552054541,0.896166713,DB0068810012601_,0.10962882,-0.070548623,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,mycophenolate mofetil,DB00688
,56490,DB00864,10012601,36,6833,49,8343,0.662789298,0.897081618,0.565996365,1.409652867,0.794417715,DB0086410012601_,0.230145866,-0.108608432,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,tacrolimus,DB00864
,56491,DB00688,10070863,77,6413,72,5306,0.457647638,0.884849149,0.631892529,1.240283966,0.624945745,DB0068810070863_,0.470090441,-0.122338101,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,mycophenolate mofetil,DB00688
,56496,DB00734,10013709,220,3830,297,4605,0.219106943,0.890653013,0.740724873,1.069647672,0.372403879,DB0073410013709_,0.987776317,-0.115800362,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,56502,DB05676,10027951,86,47043,72,25257,0.005805833,0.641266844,0.46325187,0.88997063,0.023061025,DB0567610027951_,3.769611312,-0.444309616,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,56503,DB05676,10052251,38,47091,34,25295,0.035009765,0.600325561,0.367839155,0.983375593,0.095426272,DB0567610052251_,2.349401354,-0.51028317,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,56511,DB01068,10002948,52,13711,10,6830,0.004137824,2.590226793,1.301203816,5.720104026,0.017559364,DB0106810002948_,4.042167917,0.951745437,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,56514,DB11089,10002948,38,10137,21,8386,0.150429174,1.496923495,0.855726083,2.687010541,0.284544534,DB1108910002948_,1.256865503,0.403411999,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,docusate,DB11089
,56536,DB01068,10010071,74,13689,36,6804,1,1.021712324,0.676419003,1.56857775,1,DB0106810010071_,0,0.021479969,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,56542,DB00364,10010774,75,2675,29,1371,0.209569169,1.32542182,0.848141878,2.121709283,0.360664589,DB0036410010774_,1.01980687,0.281730764,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sucralfate,DB00364
,56543,DB00455,10010774,188,9213,79,5039,0.052448354,1.301579583,0.993227668,1.718942046,0.129598589,DB0045510010774_,2.043313384,0.263578591,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,56544,DB00641,10010774,268,13856,240,12235,0.892924734,0.986027401,0.823853954,1.180685434,0.955415161,DB0064110010774_,0.045609309,-0.014071134,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,56545,DB00706,10010774,28,1047,359,15566,0.458574952,1.159550303,0.755786233,1.715082452,0.625968146,DB0070610010774_,0.468455795,0.14803226,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,tamsulosin,DB00706
,56546,DB00804,10010774,70,2930,23,876,0.708737745,0.909938213,0.557170973,1.537106181,0.826200622,DB0080410010774_,0.190917651,-0.09437858,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,dicyclomine,DB00804
,56547,DB00868,10010774,64,2920,31,1615,0.589400573,1.141836546,0.729058963,1.822535863,0.736206692,DB0086810010774_,0.306244368,0.132637971,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,benzonatate,DB00868
,56548,DB01068,10010774,240,13523,104,6736,0.248628402,1.149476195,0.907712713,1.463996869,0.407978122,DB0106810010774_,0.896541728,0.139306356,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,56550,DB14512,10010774,68,4776,36,2376,0.754110063,0.939707528,0.616474826,1.453817996,0.86176045,DB1451210010774_,0.148777947,-0.062186592,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,mometasone furoate,DB14512
,56591,DB10631,10016256,109,1187,20,191,0.596124443,0.877009795,0.525702129,1.528957541,0.741558494,DB1063110016256_,0.299001234,-0.131237118,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cranberry,DB10631
,56592,DB11365,10016256,160,1485,119,1429,0.044750844,1.293726755,1.002466985,1.673169478,0.115089863,DB1136510016256_,2.162042039,0.257527011,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sennosides,DB11365
,56593,DB00181,10020765,35,9821,24,5847,0.592142947,0.868241109,0.501433904,1.52728464,0.73840536,DB0018110020765_,0.303262338,-0.141285828,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,56597,DB00641,10020765,22,14102,32,12443,0.076213511,0.606638149,0.335634512,1.077576212,0.171821951,DB0064110020765_,1.761296506,-0.499822795,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,56601,DB01068,10020765,65,13698,26,6814,0.37405571,1.243564294,0.777258017,2.04414544,0.543883521,DB0106810020765_,0.609020172,0.217981687,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,56604,DB11089,10020765,21,10154,34,8373,0.014535675,0.509337419,0.280689947,0.903976531,0.048069283,DB1108910020765_,3.035111921,-0.674644576,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,docusate,DB11089
,56659,DB00448,10041349,54,5091,18,3106,0.027463449,1.830164254,1.054333183,3.322203011,0.07902318,DB0044810041349_,2.538014055,0.604405719,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,lansoprazole,DB00448
,56660,DB00455,10041349,129,9272,68,5050,0.880727207,1.033233302,0.762788869,1.41013816,0.950123172,DB0045510041349_,0.051163648,0.032693013,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,56661,DB00641,10041349,148,13976,138,12337,0.676799913,0.94666866,0.744614112,1.204202746,0.803980915,DB0064110041349_,0.218179748,-0.054806131,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,56662,DB00706,10041349,9,1066,195,15730,0.311206969,0.681045508,0.305922379,1.324893251,0.47871691,DB0070610041349_,0.736645859,-0.38412615,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,56664,DB01222,10041349,67,9207,43,5362,0.620974223,0.907441886,0.608653279,1.365714115,0.761443714,DB0122210041349_,0.272539024,-0.097125752,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,56687,DB01068,10045555,83,13680,52,6788,0.199401793,0.792040423,0.552618548,1.144253535,0.348326984,DB0106810045555_,1.05461363,-0.23314285,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,56690,DB11089,10045555,50,10125,58,8349,0.08124736,0.710875668,0.476477444,1.057216202,0.180492466,DB1108910045555_,1.712066244,-0.341257733,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,docusate,DB11089
,56693,DB00181,10048334,114,9742,46,5825,0.026295441,1.481782361,1.041743235,2.138230118,0.076416607,DB0018110048334_,2.571555236,0.393245661,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,56696,DB00641,10048334,53,14071,32,12443,0.102117744,1.464598848,0.92640029,2.34901432,0.214133618,DB0064110048334_,1.541155074,0.381581381,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,56697,DB00706,10048334,9,1066,44,15881,0.005578747,3.046932758,1.304228169,6.345661801,0.022332831,DB0070610048334_,3.801697461,1.114135432,female,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,tamsulosin,DB00706
,56721,DB00455,10062355,60,9341,42,5076,0.213149826,0.776334099,0.513876707,1.182340704,0.365207169,DB0045510062355_,1.0072905,-0.253172312,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,56722,DB00641,10062355,64,14060,77,12398,0.075325228,0.73293158,0.517261507,1.035489234,0.170386169,DB0064110062355_,1.769687835,-0.310702923,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,56723,DB00706,10062355,6,1069,109,15816,0.846598448,0.814412839,0.291794325,1.836683019,0.922995277,DB0070610062355_,0.080131162,-0.205287868,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,56731,DB00660,10012735,50,1207,8,359,0.111430144,1.858254141,0.863610398,4.582136748,0.22819067,DB0066010012735_,1.477573727,0.619637413,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,metaxalone,DB00660
,56732,DB00660,10019211,57,1200,15,352,0.775045883,1.114593078,0.613448885,2.146745806,0.877369497,DB0066010019211_,0.130827056,0.108489386,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,metaxalone,DB00660
,56734,DB05676,10012174,135,46994,45,25284,0.004746456,1.614068059,1.143612844,2.315895536,0.019613364,DB0567610012174_,3.93154413,0.478757737,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,apremilast,DB05676
,56735,DB05676,10030124,53,47076,27,25302,0.906768206,1.055038916,0.651699444,1.745020029,0.958455908,DB0567610030124_,0.042431719,0.053577654,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,56738,DB00186,10000087,240,16661,62,9946,4.55500508696336e-10,2.310755672,1.73900546,3.109964747,1.34526189562733e-08,DB0018610000087_,18.12409203,0.837574602,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,56739,DB00370,10000087,54,4487,27,3636,0.043077455,1.620586654,1.000824564,2.681730392,0.111831201,DB0037010000087_,2.190764674,0.482788216,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,mirtazapine,DB00370
,56741,DB00476,10016766,50,17207,13,6164,0.389800424,1.377747518,0.736710798,2.767022132,0.559701964,DB0047610016766_,0.580350844,0.320449932,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,56742,DB00722,10016766,103,25300,82,25950,0.090438966,1.288358654,0.954049113,1.744437515,0.195946724,DB0072210016766_,1.629912472,0.253369047,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,56743,DB00758,10016766,29,8271,32,10042,0.796884169,1.1002913,0.641638086,1.87967702,0.89005462,DB0075810016766_,0.116472448,0.095574963,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,56744,DB00186,10060795,59,16842,21,9987,0.048407371,1.665966148,0.996682365,2.888542009,0.122098431,DB0018610060795_,2.102927751,0.510405224,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,lorazepam,DB00186
,56746,DB00758,10060795,34,8266,23,10051,0.032503628,1.797401106,1.027429795,3.198643725,0.090207778,DB0075810060795_,2.405639628,0.586341792,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,clopidogrel,DB00758
,56747,DB08827,10060795,45,1117,22,560,1,1.025460121,0.596200215,1.812083531,1,DB0882710060795_,0,0.02514141,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,lomitapide,DB08827
,56750,DB06228,10061225,44,15868,37,16039,0.437257596,1.201995705,0.758163105,1.915207409,0.605708272,DB0622810061225_,0.501356808,0.183983263,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,56753,DB00512,10086737,65,4672,64,5034,0.657677967,1.094303131,0.76098833,1.574068324,0.790771939,DB0051210086737_,0.234745672,0.090117751,NA,10086737,Vancomycin infusion reaction,10040785,Skin and subcutaneous tissue disorders,Skin,vancomycin,DB00512
,56754,DB05259,10016322,132,11138,26,2702,0.36454667,1.231606224,0.802233298,1.958871212,0.534149574,DB0525910016322_,0.627079378,0.208319191,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,56756,DB00758,10011224,149,8151,135,9939,0.013700647,1.345778831,1.056955765,1.714789967,0.045755863,DB0075810011224_,3.084435353,0.296972902,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,56764,DB00091,10003239,130,5380,28,2642,3.31604739584863e-05,2.279810259,1.50171399,3.572904669,0.000309855,DB0009110003239_,8.07940503,0.82409222,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclosporine,DB00091
,56765,DB00005,10028034,160,127922,19,42400,2.29002841953517e-06,2.79128462,1.72967277,4.758502944,2.98208555895377e-05,DB0000510028034_,10.42030256,1.026501927,female,10028034,Mouth ulceration,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,56767,DB00005,10017626,65,128017,16,42403,0.367606491,1.345600664,0.76959922,2.491979115,0.537300115,DB0000510017626_,0.621198467,0.296840504,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,etanercept,DB00005
,56768,DB05676,10037844,1541,45588,798,24531,0.390127203,1.039118597,0.951994064,1.134849837,0.560025018,DB0567610037844_,0.579773821,0.038372851,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,56769,DB01175,10022061,83,10641,10,4882,4.75487295067663e-06,3.807313486,1.968010959,8.240029063,5.6616913027649e-05,DB0117510022061_,9.779202801,1.336923819,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,56770,DB01175,10022086,145,10579,40,4852,0.003979356,1.662537364,1.162255181,2.426405499,0.017009085,DB0117510022086_,4.074007688,0.508344968,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,56771,DB00158,10022093,263,16552,21,8083,3.00463372883932e-24,6.115998659,3.914587947,10.05387365,4.37544584834025e-22,DB0015810022093_,49.18086362,1.810908069,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,56772,DB01175,10022093,61,10663,7,4885,6.34625823256395e-05,3.992427528,1.823046668,10.35406129,0.000540105,DB0117510022093_,7.523747182,1.384399449,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,56774,DB00598,10021097,48,1540,49,979,0.025711879,0.622878844,0.405990651,0.955158224,0.075055444,DB0059810021097_,2.589528184,-0.473403251,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,labetalol,DB00598
,56777,DB00656,10035669,25,11988,48,6571,2.03997802346748e-07,0.285505448,0.168548936,0.472835887,3.45383718820244e-06,DB0065610035669_,12.57602472,-1.253494169,male,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,trazodone,DB00656
,56778,DB01224,10035669,30,8078,37,5880,0.034755189,0.590227343,0.351710382,0.983086203,0.094960992,DB0122410035669_,2.354289084,-0.527247489,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,quetiapine,DB01224
,56779,DB05676,10041349,108,47021,67,25262,0.38265417,0.86602181,0.632388971,1.193350676,0.552777602,DB0567610041349_,0.592799524,-0.143845186,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,56790,DB00158,10055798,53,16762,37,8067,0.090658516,0.689377552,0.444142403,1.080148216,0.196249462,DB0015810055798_,1.628368665,-0.371966186,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,folic acid,DB00158
,56791,DB00264,10055798,138,29469,151,24741,0.028315376,0.767288529,0.604274167,0.973604663,0.080968506,DB0026410055798_,2.513695015,-0.26489237,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,56792,DB00695,10055798,171,27878,130,20398,0.769885835,0.9624312,0.761122516,1.21939508,0.873962496,DB0069510055798_,0.134717815,-0.038292695,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,furosemide,DB00695
,56793,DB01222,10055798,42,9232,34,5371,0.154167417,0.718709666,0.445761451,1.166333905,0.289749423,DB0122210055798_,1.238738787,-0.330297805,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,budesonide,DB01222
,56794,DB01373,10055798,81,22639,28,7353,0.739307645,0.939577411,0.604124014,1.501415971,0.850094527,DB0137310055798_,0.162407728,-0.062325068,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,calcium,DB01373
,56798,DB14500,10055798,44,7765,23,4050,1,0.997788329,0.588633817,1.733634352,1,DB1450010055798_,0,-0.00221412,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,potassium,DB14500
,56799,DB05676,10047700,1807,45322,495,24834,3.04489897041792e-46,2.000259041,1.80766883,2.216518723,1.5244794178559e-43,DB0567610047700_,98.58950601,0.693276693,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,56817,DB00983,10035664,124,3377,67,1673,0.584168845,0.916896004,0.671616539,1.260885898,0.732021267,DB0098310035664_,0.311945712,-0.086761222,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,formoterol,DB00983
,56820,DB05676,10003988,458,46671,229,25100,0.376823836,1.075619664,0.915156661,1.267057883,0.546698746,DB0567610003988_,0.603857368,0.072896927,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,56821,DB05676,10022437,747,46382,336,24993,0.006331197,1.197949719,1.050842608,1.367945011,0.024721905,DB0567610022437_,3.700065579,0.180611528,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,56826,DB05679,10008479,33,6898,24,4885,1,0.973733405,0.557497979,1.724084334,1,DB0567910008479_,0,-0.026617724,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,56827,DB00153,10028411,135,7288,26,3413,7.74985026394429e-06,2.431414215,1.585550781,3.863977389,8.68480519459784e-05,DB0015310028411_,9.351350496,0.88847307,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,56838,DB00169,10003445,61,38630,37,18138,0.233195124,0.774125673,0.506106541,1.198537738,0.389771726,DB0016910003445_,0.94219403,-0.25602105,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,56839,DB00203,10003445,151,13727,84,8854,0.313670427,1.159507987,0.880942084,1.534756332,0.481140708,DB0020310003445_,0.73159552,0.147995766,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,56841,DB00169,10019663,38,38653,26,18149,0.141492419,0.68623855,0.405783642,1.177512149,0.271924745,DB0016910019663_,1.302229925,-0.376529971,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,cholecalciferol,DB00169
,56845,DB00316,10023126,70,65404,63,36890,0.008546181,0.626676587,0.439378419,0.895488293,0.031393647,DB0031610023126_,3.461149729,-0.467324682,NA,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,56850,DB00374,10000381,59,17657,17,5707,0.789296356,1.121738241,0.644443751,2.054518204,0.885851185,DB0037410000381_,0.121206306,0.114879483,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,56853,DB00374,10002855,281,17435,55,5669,0.000414918,1.661125088,1.23839129,2.263923211,0.002640704,DB0037410002855_,5.93670962,0.507495137,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,treprostinil,DB00374
,56854,DB00972,10002855,44,2460,12,1167,0.111310614,1.739197073,0.898762836,3.631583625,0.228025834,DB0097210002855_,1.478296349,0.553423555,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,azelastine,DB00972
,56858,DB00972,10019211,161,2343,47,1132,0.002755612,1.654808651,1.178844489,2.360300003,0.012607704,DB0097210019211_,4.373447201,0.503685383,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,azelastine,DB00972
,56865,DB00559,10048634,54,9605,23,3283,0.361515406,0.802491826,0.483341367,1.372305083,0.531396513,DB0055910048634_,0.632246808,-0.22003361,NA,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,56867,DB00559,10053483,64,9595,38,3268,0.008437244,0.573661045,0.377334456,0.882806221,0.031077041,DB0055910053483_,3.471285968,-0.555716571,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,56869,DB00374,10053505,266,17450,51,5673,0.000361602,1.69551528,1.250550622,2.338755978,0.002357256,DB0037410053505_,6.050256912,0.527986694,NA,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,56873,DB00374,10065473,58,17658,16,5708,0.684486305,1.171781314,0.663932044,2.185693763,0.809435273,DB0037410065473_,0.211418469,0.158525082,NA,10065473,Infusion site irritation,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,56879,DB01261,10002855,50,3731,34,3269,0.272627664,1.288441603,0.814700409,2.059915282,0.435544773,DB0126110002855_,0.831157679,0.253433428,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,sitagliptin,DB01261
,56881,DB01261,10009033,33,3748,30,3273,0.899566305,0.960582363,0.566573539,1.634470503,0.956532328,DB0126110009033_,0.044440693,-0.04021555,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sitagliptin,DB01261
,56892,DB00203,10042209,71,13807,21,8917,0.001207381,2.183451765,1.324937069,3.744262158,0.006436018,DB0020310042209_,5.045845251,0.780907003,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,sildenafil,DB00203
,56893,DB06403,10042209,47,21424,8,6653,0.15120505,1.824318931,0.853551286,4.472767716,0.285547263,DB0640310042209_,1.253347718,0.601206729,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,ambrisentan,DB06403
,56896,DB08895,10010774,295,27819,49,6597,0.019151444,1.427659319,1.050885663,1.975840734,0.059732508,DB0889510010774_,2.817878876,0.356036263,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,56898,DB01156,10039897,41,13581,26,6302,0.236404733,0.731732814,0.436624228,1.247160263,0.393621032,DB0115610039897_,0.932366681,-0.312339839,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,56899,DB00575,10053762,162,5082,151,3678,0.031039772,0.776482565,0.615594651,0.979841635,0.086999403,DB0057510053762_,2.441854027,-0.25298109,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,clonidine,DB00575
,56905,DB00761,10021036,91,15216,47,8578,0.657529873,1.091519588,0.758611282,1.588664235,0.790692277,DB0076110021036_,0.234846417,0.087570843,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,56926,DB00108,10035669,39,10155,27,3268,0.003586671,0.464860568,0.276896301,0.791011256,0.015620739,DB0010810035669_,4.159155796,-0.766017772,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,natalizumab,DB00108
,56929,DB00316,10035669,133,65341,148,36805,1.59136776750885e-08,0.506177156,0.397321421,0.644373264,3.40905474889733e-07,DB0031610035669_,14.8916606,-0.68086856,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,56931,DB00761,10035669,24,15283,40,8585,1.99660827191087e-05,0.337056985,0.194215976,0.573382908,0.000199433,DB0076110035669_,8.52003118,-1.087503268,male,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,56933,DB00863,10035669,26,10647,35,5805,0.000650103,0.405044583,0.233889727,0.693188975,0.003851239,DB0086310035669_,5.559360337,-0.903758137,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,ranitidine,DB00863
,56938,DB08875,10010774,31,612,31,1212,0.009315766,1.979678711,1.151991321,3.401872408,0.033628362,DB0887510010774_,3.392385452,0.682934564,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,cabozantinib,DB08875
,56939,DB01076,10013573,817,24930,807,24776,0.919660549,1.006137912,0.910289366,1.112133039,0.964404362,DB0107610013573_,0.03624461,0.006119152,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,56941,DB08875,10016256,93,550,130,1113,0.012911219,1.447433421,1.075430249,1.94251312,0.043640636,DB0887510016256_,3.131766556,0.369791933,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cabozantinib,DB08875
,56942,DB08875,10028813,71,572,86,1157,0.002717976,1.66949848,1.182039406,2.351967905,0.012469153,DB0887510028813_,4.38449745,0.51252327,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cabozantinib,DB08875
,56943,DB00264,10029410,64,29543,37,24855,0.072171676,1.455236378,0.95571993,2.245101645,0.165064822,DB0026410029410_,1.801417024,0.375168347,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,56944,DB00381,10029410,80,29280,53,22834,0.382240145,1.177124243,0.821233704,1.699301705,0.552331283,DB0038110029410_,0.593607262,0.163074382,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,56945,DB00497,10029410,48,19219,34,16341,0.439096875,1.200349355,0.757238299,1.921794835,0.607471847,DB0049710029410_,0.498449448,0.182612643,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,56946,DB00904,10029410,66,23003,46,14410,0.627017534,0.898809744,0.607212723,1.340383325,0.766494088,DB0090410029410_,0.265928294,-0.106683898,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,56947,DB01076,10029410,49,25698,36,25547,0.192584938,1.353100618,0.861868061,2.142633214,0.339917128,DB0107610029410_,1.079053431,0.302398713,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,56958,DB00264,10051128,33,29574,18,24874,0.159789449,1.541958029,0.843128334,2.909370417,0.297163362,DB0026410051128_,1.213473253,0.433053057,NA,10051128,Blood pressure inadequately controlled,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,56965,DB01076,10051398,53,25694,141,25442,1.18722572779784e-10,0.372189877,0.266009347,0.514117934,3.81494232948242e-09,DB0107610051398_,19.38434029,-0.988351132,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,atorvastatin,DB01076
,56967,DB00843,10012174,31,2163,33,2140,0.80210975,0.929447652,0.548324808,1.571754142,0.892948956,DB0084310012174_,0.11322586,-0.073164792,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,donepezil,DB00843
,56968,DB00973,10012174,44,3807,46,2975,0.199335673,0.747517905,0.48156739,1.158948874,0.348257771,DB0097310012174_,1.054812351,-0.290997021,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ezetimibe,DB00973
,56969,DB08899,10012174,10,239,100,8033,0.001545064,3.360202711,1.54367518,6.547710118,0.007880472,DB0889910012174_,4.843367494,1.212001303,female,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,enzalutamide,DB08899
,56973,DB00758,10021789,63,8237,62,10012,0.242464128,1.235076348,0.85473351,1.785226039,0.400677078,DB0075810021789_,0.914599467,0.211132788,NA,10021789,Infection,10021881,Infections and infestations,Infec,clopidogrel,DB00758
,56975,DB00973,10021789,37,3814,19,3002,0.138601481,1.532679438,0.857071502,2.827615241,0.267838547,DB0097310021789_,1.317370915,0.42701747,NA,10021789,Infection,10021881,Infections and infestations,Infec,ezetimibe,DB00973
,56980,DB00706,10000059,9,1066,143,15782,1,0.931777959,0.416350424,1.825989293,1,DB0070610000059_,0,-0.070660734,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,tamsulosin,DB00706
,56981,DB00811,10000059,21,2777,35,4121,0.784658461,0.890376523,0.491394852,1.576584196,0.883059927,DB0081110000059_,0.124362214,-0.116110847,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ribavirin,DB00811
,56983,DB08934,10000059,60,4429,89,6115,0.738242982,0.930783453,0.657881814,1.309107431,0.849277492,DB0893410000059_,0.1633693,-0.071728625,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,sofosbuvir,DB08934
,56985,DB00537,10029148,42,7515,34,4264,0.150263781,0.700952327,0.434602329,1.137877707,0.284344226,DB0053710029148_,1.25756971,-0.355315401,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,ciprofloxacin,DB00537
,56986,DB00706,10029148,50,1025,114,15811,1.49146680560587e-21,6.763923713,4.7214808,9.573812769,1.82765524407227e-19,DB0070610029148_,43.14608291,1.911603153,female,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,tamsulosin,DB00706
,56997,DB00820,10016100,33,11882,22,5794,0.253054825,0.731430925,0.413419054,1.318184729,0.413459805,DB0082010016100_,0.883194976,-0.312752492,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,56998,DB06228,10016100,56,15856,70,16006,0.246558638,0.807574993,0.557516763,1.165097847,0.405668959,DB0622810016100_,0.902217824,-0.213719357,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,57002,DB00374,10060933,90,17626,24,5700,0.445430222,1.212682575,0.765084596,1.99196277,0.613376645,DB0037410060933_,0.488776103,0.192834909,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,57003,DB00820,10060933,93,11822,31,5785,0.068127906,1.467996062,0.966981801,2.284234842,0.157934648,DB0082010060933_,1.845573952,0.383898248,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,57004,DB06228,10060933,72,15840,71,16005,0.933259781,1.024651722,0.727326495,1.443823203,0.973924897,DB0622810060933_,0.026421086,0.024352771,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,57005,DB00904,10000059,306,22763,134,14322,0.000455513,1.436767959,1.167672346,1.775605704,0.002857052,DB0090410000059_,5.857964799,0.362396118,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,57006,DB08868,10000059,76,9126,28,2483,0.186087008,0.738523299,0.471929251,1.186198468,0.331572702,DB0886810000059_,1.10390818,-0.303102629,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,fingolimod,DB08868
,57007,DB00476,10000060,99,17158,28,6149,0.31249836,1.267086609,0.824839884,2.004880539,0.479955189,DB0047610000060_,0.734062535,0.236720257,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,57009,DB00557,10000087,71,5916,22,3045,0.036547518,1.6610111,1.014918964,2.820763289,0.098655075,DB0055710000087_,2.316125605,0.507426513,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,hydroxyzine,DB00557
,57010,DB08868,10000087,78,9124,18,2493,0.617457763,1.184001996,0.700818725,2.105242,0.758456796,DB0886810000087_,0.276469441,0.168900222,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,fingolimod,DB08868
,57011,DB00476,10001551,54,17203,24,6153,0.369404609,0.804748039,0.488533317,1.362554347,0.539058995,DB0047610001551_,0.617930261,-0.217226046,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,duloxetine,DB00476
,57013,DB08868,10001551,224,8978,113,2398,1.75910104791841e-07,0.529526148,0.41846249,0.673001777,3.02307754459204e-06,DB0886810001551_,12.70923519,-0.635772734,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,fingolimod,DB08868
,57014,DB08868,10002855,226,8976,49,2462,0.157431134,1.265049185,0.922063846,1.765931289,0.294104734,DB0886810002855_,1.223819338,0.235111003,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,fingolimod,DB08868
,57015,DB08868,10003239,213,8989,46,2465,0.167779777,1.269746447,0.916352536,1.792343656,0.307881279,DB0886810003239_,1.178041028,0.238817233,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fingolimod,DB08868
,57016,DB00476,10003481,49,17208,24,6153,0.230432132,0.730041725,0.438969872,1.245177766,0.38644213,DB0047610003481_,0.950773151,-0.31465359,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,duloxetine,DB00476
,57018,DB08868,10003481,124,9078,66,2445,2.2980858395549e-05,0.506029445,0.371104476,0.695338941,0.000224847,DB0886810003481_,8.400089729,-0.681160419,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,fingolimod,DB08868
,57025,DB08868,10005364,36,9166,24,2487,0.001268985,0.407031424,0.235753504,0.714611143,0.006690766,DB0886810005364_,5.007026944,-0.898864888,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,fingolimod,DB08868
,57026,DB00476,10005750,156,17101,47,6130,0.336963502,1.189763031,0.852434305,1.687995358,0.50610472,DB0047610005750_,0.681011674,0.173754154,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,duloxetine,DB00476
,57027,DB00557,10005750,53,5934,12,3055,0.008108312,2.273655303,1.197312442,4.682592113,0.030117195,DB0055710005750_,3.502659019,0.821388802,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,hydroxyzine,DB00557
,57030,DB00904,10008612,37,23032,23,14433,1,1.008088855,0.58306776,1.777709484,1,DB0090410008612_,0,0.008056316,NA,10008612,Cholecystitis,10019805,Hepatobiliary disorders,Hepat,ondansetron,DB00904
,57037,DB00904,10008796,38,23031,25,14431,0.897108162,0.952434821,0.559864911,1.646964716,0.956338178,DB0090410008796_,0.044643686,-0.048733604,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,ondansetron,DB00904
,57039,DB00476,10013946,85,17172,23,6154,0.273487497,1.32439044,0.826530993,2.202624606,0.436467447,DB0047610013946_,0.829041484,0.280952309,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,57041,DB00904,10013946,196,22873,75,14381,0.000207355,1.643065714,1.2518903,2.175587596,0.001484697,DB0090410013946_,6.512544261,0.496563834,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,57042,DB08868,10013946,45,9157,10,2501,0.624848189,1.229036231,0.609506482,2.739119096,0.764509819,DB0886810013946_,0.26852041,0.20623031,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,fingolimod,DB08868
,57050,DB00557,10019211,295,5692,72,2995,9.06618599196191e-10,2.155702525,1.654038997,2.840432746,2.53920829833478e-08,DB0055710019211_,17.48882841,0.768116668,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,57064,DB00904,10022004,142,22927,32,14424,1.16138362673828e-08,2.791665901,1.89026639,4.237475143,2.5761154961026e-07,DB0090410022004_,15.17181301,1.026638515,female,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,57065,DB08868,10022004,75,9127,18,2493,0.704289116,1.1380937,0.671994046,2.027437662,0.822711349,DB0886810022004_,0.19514987,0.12935467,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,57066,DB00904,10022437,323,22746,161,14295,0.016516815,1.260800497,1.039144822,1.534710518,0.053133748,DB0090410022437_,2.934943002,0.231746834,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,57067,DB08868,10022437,169,9033,37,2474,0.231610522,1.250959498,0.869452132,1.842526361,0.38786204,DB0886810022437_,0.94710557,0.223910855,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,fingolimod,DB08868
,57071,DB00557,10025482,178,5809,57,3010,0.001615207,1.618038821,1.190245085,2.227869987,0.008161419,DB0055710025482_,4.808337194,0.481214811,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,57076,DB00476,10047942,130,17127,50,6127,0.671328453,0.930118857,0.665453669,1.317822377,0.800574751,DB0047610047942_,0.22242537,-0.072442898,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,duloxetine,DB00476
,57077,DB00557,10047942,50,5937,27,3040,0.810010025,0.948234157,0.581089714,1.578634603,0.897715289,DB0055710047942_,0.107902311,-0.053153807,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,hydroxyzine,DB00557
,57078,DB08868,10047942,630,8572,142,2369,0.032955026,1.226098743,1.014344069,1.490039751,0.091181355,DB0886810047942_,2.394904846,0.203837375,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,fingolimod,DB08868
,57087,DB00476,10059570,49,17208,13,6164,0.388123422,1.35011896,0.720713267,2.714813272,0.558101925,DB0047610059570_,0.583213672,0.300192707,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,duloxetine,DB00476
,57089,DB00904,10059570,72,22997,50,14406,0.57730041,0.902062777,0.619801236,1.321956135,0.726342542,DB0090410059570_,0.319733555,-0.103071164,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,ondansetron,DB00904
,57090,DB08868,10059570,106,9096,26,2485,0.670991967,1.11379269,0.717838906,1.786860424,0.800371966,DB0886810059570_,0.222678702,0.107771029,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,fingolimod,DB08868
,57095,DB00476,10061428,234,17023,96,6081,0.257697844,0.870751185,0.68245037,1.118162915,0.418549006,DB0047610061428_,0.870961297,-0.138399009,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,duloxetine,DB00476
,57096,DB08868,10061428,59,9143,25,2486,0.081343201,0.641716617,0.394776922,1.071677375,0.180621417,DB0886810061428_,1.711352055,-0.443608479,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,fingolimod,DB08868
,57109,DB01240,10010264,378,5373,136,1440,0.005364739,0.74493329,0.605252638,0.920946764,0.021634269,DB0124010010264_,3.83347669,-0.294460608,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,57110,DB01240,10039163,246,5505,79,1497,0.213942068,0.846780768,0.650135408,1.112662214,0.366170748,DB0124010039163_,1.004655529,-0.166313451,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,epoprostenol,DB01240
,57119,DB00635,10062237,107,32946,112,23682,0.005963892,0.686739869,0.52162239,0.903695474,0.023553586,DB0063510062237_,3.748477209,-0.375799706,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,57120,DB00722,10062237,92,25311,118,25914,0.111780719,0.798240415,0.600717833,1.057967547,0.228739291,DB0072210062237_,1.475172392,-0.225345454,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,57121,DB01098,10062237,26,8123,39,7170,0.045479014,0.588478971,0.343588379,0.9926176,0.116478211,DB0109810062237_,2.150051052,-0.530214087,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,rosuvastatin,DB01098
,57122,DB01136,10062237,58,9826,75,11040,0.434249473,0.868884678,0.605216898,1.242010781,0.602796198,DB0113610062237_,0.506176119,-0.140544869,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,carvedilol,DB01136
,57124,DB00203,10011878,41,13837,24,8914,0.799460491,1.100546923,0.648884629,1.905492258,0.891654641,DB0020310011878_,0.114676396,0.095807259,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,sildenafil,DB00203
,57126,DB00203,10030041,35,13843,21,8917,0.891242099,1.07359411,0.607338392,1.942302142,0.954816394,DB0020310030041_,0.046236214,0.071012001,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,sildenafil,DB00203
,57127,DB06403,10030041,42,21429,16,6645,0.5357431,0.81399452,0.447831819,1.552036129,0.692245662,DB0640310030041_,0.367814383,-0.205801645,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,ambrisentan,DB06403
,57131,DB00136,10038435,56,2036,48,1634,0.764672904,0.936343903,0.62165211,1.414913716,0.870105077,DB0013610038435_,0.139141296,-0.065772453,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,calcitriol,DB00136
,57144,DB00682,10035669,23,19436,46,16318,0.000603089,0.419796013,0.242757557,0.707305325,0.003613861,DB0068210035669_,5.622978523,-0.867986368,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,warfarin,DB00682
,57146,DB00682,10058046,34,19425,17,16347,0.090983629,1.683060641,0.914148617,3.213725231,0.196815462,DB0068210058046_,1.62548873,0.520613946,NA,10058046,Post procedural complication,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,57149,DB01036,10013968,54,1447,8,414,0.086827859,1.930600356,0.903663428,4.736503274,0.189770115,DB0103610013968_,1.661941863,0.65783102,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tolterodine,DB01036
,57157,DB00264,10046735,251,29356,113,24779,1.30150173151281e-08,1.874870065,1.494639649,2.363928919,2.84727199440816e-07,DB0026410046735_,15.07173431,0.628539358,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,57160,DB00482,10011906,110,8149,86,2985,3.70785088566217e-07,0.46855194,0.349009266,0.63077488,5.90314115866931e-06,DB0048210011906_,12.04002595,-0.75810832,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,57161,DB00490,10011906,126,3944,93,1483,2.36717786159154e-06,0.509486176,0.383945143,0.678081913,3.06728747378475e-05,DB0049010011906_,10.39213185,-0.67435256,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,57165,DB00193,10000059,248,19072,74,8628,0.001588251,1.516100225,1.163426507,1.995671801,0.008047646,DB0019310000059_,4.82237562,0.416141397,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,57166,DB00567,10000059,61,4458,14,2067,0.016967731,2.020051127,1.113827262,3.920644246,0.054303764,DB0056710000059_,2.913161738,0.703122821,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,cephalexin,DB00567
,57167,DB00586,10000059,118,6991,29,2776,0.020800314,1.615671925,1.065830253,2.522658604,0.063742682,DB0058610000059_,2.752900896,0.479750923,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,diclofenac,DB00586
,57173,DB00425,10001760,160,12535,24,7460,4.69445623898013e-13,3.967342309,2.570181928,6.380143167,2.19561890109595e-11,DB0042510001760_,24.54197206,1.378096427,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,zolpidem,DB00425
,57175,DB00930,10013700,59,1231,12,630,0.002863387,2.515243682,1.325574781,5.179813143,0.013020347,DB0093010013700_,4.341241959,0.92236969,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,colesevelam,DB00930
,57177,DB09053,10019211,66,2219,71,3981,0.003838124,1.667648172,1.169391493,2.375086612,0.016496624,DB0905310019211_,4.104599553,0.511414354,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ibrutinib,DB09053
,57181,DB01267,10054112,133,2719,170,3545,0.905557499,1.020025139,0.802174743,1.294862757,0.957861963,DB0126710054112_,0.0430516,0.019827273,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,paliperidone,DB01267
,57186,DB00575,10005483,26,5218,52,3777,1.47843171767261e-05,0.361959803,0.216553228,0.591552597,0.000153025,DB0057510005483_,8.784912366,-1.016222116,male,10005483,Blood creatinine increased,10022891,Investigations,Inv,clonidine,DB00575
,57189,DB00441,10038435,20,2254,31,1863,0.033074427,0.533333132,0.287052173,0.969625127,0.091451012,DB0044110038435_,2.391951838,-0.628609036,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,gemcitabine,DB00441
,57190,DB00575,10038435,63,5181,59,3770,0.167525528,0.777020775,0.534632322,1.130624879,0.30757577,DB0057510038435_,1.179033817,-0.252288192,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,clonidine,DB00575
,57193,DB00575,10043554,30,5214,25,3804,0.681788235,0.875503962,0.496826613,1.555226052,0.807552611,DB0057510043554_,0.213747073,-0.132955601,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,clonidine,DB00575
,57200,DB00264,10000891,122,29485,153,24739,0.001017999,0.669048152,0.52269786,0.854880612,0.005586825,DB0026410000891_,5.187344104,-0.401899245,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,metoprolol,DB00264
,57208,DB00281,10047302,40,11418,69,5602,1.17241577323122e-10,0.284429884,0.187417398,0.426503571,3.77658683815964e-09,DB0028110047302_,19.39444519,-1.257268509,male,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,lidocaine,DB00281
,57213,DB01012,10021097,78,10554,66,8619,0.866607813,0.96512789,0.685547997,1.362295436,0.939796451,DB0101210021097_,0.062091969,-0.035494657,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,cinacalcet,DB01012
,57214,DB00126,10007559,95,10076,73,5872,0.077545059,0.75843161,0.552141599,1.045375035,0.174203827,DB0012610007559_,1.747529248,-0.27650265,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,ascorbic acid,DB00126
,57216,DB01020,10007559,51,1762,81,1797,0.016420723,0.642216149,0.440439194,0.929065503,0.052891208,DB0102010007559_,2.939518162,-0.442830351,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,isosorbide mononitrate,DB01020
,57219,DB00254,10047899,61,5874,24,3364,0.140487156,1.455539705,0.892250875,2.446094597,0.270508014,DB0025410047899_,1.307453556,0.375376763,NA,10047899,Weight increased,10022891,Investigations,Inv,doxycycline,DB00254
,57220,DB00381,10047899,447,28913,217,22670,3.98379491269496e-09,1.615107495,1.368946873,1.910136918,9.77722215501279e-08,DB0038110047899_,16.14062533,0.479401515,NA,10047899,Weight increased,10022891,Investigations,Inv,amlodipine,DB00381
,57222,DB00758,10047899,125,8175,79,9995,3.70766137810719e-06,1.93444507,1.44566729,2.601733807,4.54339763746142e-05,DB0075810047899_,9.999250355,0.6598205,NA,10047899,Weight increased,10022891,Investigations,Inv,clopidogrel,DB00758
,57226,DB00381,10062060,37,29323,25,22862,0.610648829,1.153878212,0.676055705,2.000300718,0.752793844,DB0038110062060_,0.283963869,0.143128627,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,57240,DB00060,10047899,69,9439,8,2457,0.023546749,2.244937321,1.076068397,5.413599028,0.070161117,DB0006010047899_,2.65696101,0.808677601,NA,10047899,Weight increased,10022891,Investigations,Inv,interferon beta-1a,DB00060
,57249,DB01098,10038695,37,8112,37,7172,0.641186752,0.884130198,0.544507539,1.435574549,0.777959881,DB0109810038695_,0.251080323,-0.123150944,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,57251,DB01275,10038695,69,3910,52,3297,0.581442593,1.118852389,0.766911129,1.640968825,0.729765132,DB0127510038695_,0.315032534,0.112303507,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydralazine,DB01275
,57252,DB00695,10045555,89,27960,79,20449,0.21170915,0.823951932,0.601366935,1.130653142,0.363480516,DB0069510045555_,1.012029585,-0.193643085,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,57256,DB08908,10024860,34,10639,16,3263,0.179809966,0.651763809,0.349542931,1.26623975,0.323632971,DB0890810024860_,1.128145212,-0.428073039,NA,10024860,Loss of control of legs,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,57257,DB08908,10042772,47,10626,14,3265,1,1.031543589,0.557469833,2.031492818,1,DB0890810042772_,0,0.031056311,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,57258,DB00213,10054236,123,18772,67,13354,0.089241674,1.305952468,0.961221316,1.787450095,0.194045366,DB0021310054236_,1.639663304,0.266932635,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,57260,DB00316,10054236,195,65279,128,36825,0.182544945,0.85940451,0.683866851,1.08305154,0.327108694,DB0031610054236_,1.117462767,-0.15151556,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,57264,DB00425,10054236,41,12654,25,7459,0.898936709,0.966687171,0.573460662,1.660251736,0.956490275,DB0042510054236_,0.044484657,-0.03388034,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,zolpidem,DB00425
,57265,DB00455,10054236,44,9357,15,5103,0.133008469,1.599695292,0.87223672,3.097895624,0.259954465,DB0045510054236_,1.347248797,0.469813169,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,loratadine,DB00455
,57268,DB00682,10054236,104,19355,43,16321,5.93406681861089e-05,2.039397459,1.415643698,2.983213976,0.000510897,DB0068210054236_,7.579341962,0.712654401,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,57269,DB00695,10054236,122,27927,58,20470,0.006405948,1.541775441,1.118323187,2.146833545,0.024941542,DB0069510054236_,3.691220507,0.432934636,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,57270,DB00927,10054236,41,7456,21,4995,0.363988858,1.30793127,0.754173918,2.332638878,0.533599951,DB0092710054236_,0.628108876,0.268446706,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,famotidine,DB00927
,57271,DB01075,10054236,63,19885,35,11062,1,1.001337651,0.651798111,1.561064232,1,DB0107510054236_,0,0.001336757,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,57272,DB01137,10054236,36,7736,44,5549,0.022395892,0.586916082,0.366505033,0.934343675,0.067497106,DB0113710054236_,2.695670557,-0.53287343,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,levofloxacin,DB01137
,57278,DB11089,10054236,50,10125,33,8374,0.322639494,1.253107655,0.790692318,2.009912943,0.490958931,DB1108910054236_,0.711394798,0.22562659,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,docusate,DB11089
,57281,DB04868,10011906,47,1594,63,1453,0.052081553,0.680128663,0.452780382,1.015554509,0.128952866,DB0486810011906_,2.048308325,-0.385473289,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,nilotinib,DB04868
,57282,DB00091,10011906,86,5424,105,2565,1.91989200488084e-10,0.387374367,0.286695784,0.522249686,5.98628248496949e-09,DB0009110011906_,18.93379524,-0.948363697,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,57283,DB00489,10011906,46,1037,62,1072,0.199862782,0.767070168,0.507031522,1.153395879,0.348819311,DB0048910011906_,1.053201224,-0.265176998,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sotalol,DB00489
,57284,DB00374,10043071,159,17557,39,5685,0.134612827,1.320089094,0.92369871,1.927724594,0.26209616,DB0037410043071_,1.339043821,0.27769923,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,treprostinil,DB00374
,57285,DB00563,10043521,77,46569,10,15338,0.002721642,2.536171029,1.30684306,5.500114908,0.012483792,DB0056310043521_,4.38332411,0.930655475,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,57286,DB00005,10070325,120,127962,61,42358,0.007540979,0.651189294,0.474481751,0.901631985,0.028406335,DB0000510070325_,3.561143078,-0.428954905,NA,10070325,Mycobacterium tuberculosis complex test positive,10022891,Investigations,Inv,etanercept,DB00005
,57292,DB00165,10000059,39,2106,15,1351,0.09360445,1.667672653,0.894692277,3.269773706,0.201102863,DB0016510000059_,1.603938744,0.511429034,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,pyridoxine,DB00165
,57295,DB08882,10003549,43,954,30,963,0.152045493,1.446581078,0.878344582,2.410106642,0.286806023,DB0888210003549_,1.24894917,0.369202895,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,linagliptin,DB08882
,57296,DB00165,10012174,35,2110,16,1350,0.312121291,1.399456586,0.750974694,2.719113792,0.479632162,DB0016510012174_,0.734735797,0.336084009,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,pyridoxine,DB00165
,57297,DB00433,10012174,255,7401,183,5837,0.35280527,1.099003463,0.902414914,1.340443116,0.522582431,DB0043310012174_,0.648972545,0.094403827,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,prochlorperazine,DB00433
,57299,DB01268,10012174,80,2063,95,3035,0.183219026,1.23880842,0.90343797,1.695148952,0.327936542,DB0126810012174_,1.114935159,0.214149966,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,sunitinib,DB01268
,57301,DB08882,10012735,63,934,38,955,0.013898457,1.694714653,1.103246791,2.633283026,0.046290034,DB0888210012735_,3.072828589,0.52751438,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,linagliptin,DB08882
,57304,DB00264,10027417,67,29540,81,24811,0.031384046,0.694753403,0.494772552,0.972788428,0.087750641,DB0026410027417_,2.433256107,-0.364198312,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,57312,DB00264,10040070,84,29523,99,24793,0.025513328,0.712556378,0.526074025,0.963248709,0.074637489,DB0026410040070_,2.595112367,-0.338896242,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,metoprolol,DB00264
,57313,DB00338,10040070,81,33593,75,22197,0.040303812,0.713643229,0.514545683,0.990815823,0.106257341,DB0033810040070_,2.241891381,-0.337372121,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,omeprazole,DB00338
,57314,DB00433,10040070,48,7608,34,5986,0.657336849,1.110736131,0.700093647,1.779988554,0.790542601,DB0043310040070_,0.235035733,0.105022977,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,57315,DB00451,10040070,101,47170,52,15367,0.008435632,0.632768712,0.448299801,0.902509701,0.031076466,DB0045110040070_,3.47130448,-0.457650307,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,57319,DB11089,10040070,39,10136,54,8353,0.015881015,0.595202754,0.383418571,0.916374363,0.05154442,DB1108910040070_,2.96531132,-0.518853168,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,docusate,DB11089
,57335,DB00537,10019063,49,7508,20,4278,0.258085374,1.395953475,0.813334488,2.48269355,0.419010133,DB0053710019063_,0.869860176,0.333577676,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,ciprofloxacin,DB00537
,57337,DB00864,10008531,58,6811,66,8326,0.717449034,1.074243749,0.74056875,1.554658105,0.833049049,DB0086410008531_,0.182662756,0.071616925,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,57348,DB00795,10022061,68,4501,10,1493,0.011897725,2.255474241,1.150700009,4.92727012,0.040890651,DB0079510022061_,3.196853818,0.813360257,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,57350,DB00795,10040753,65,4504,13,1490,0.112494877,1.653896052,0.899716659,3.2808237,0.229816022,DB0079510040753_,1.470476195,0.503133748,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,sulfasalazine,DB00795
,57353,DB00448,10003988,95,5050,35,3089,0.010470395,1.660186777,1.112683016,2.527980145,0.036914269,DB0044810003988_,3.299157099,0.506930112,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lansoprazole,DB00448
,57355,DB00921,10003988,53,5792,25,4878,0.016441942,1.785358969,1.088246789,3.003257657,0.052940094,DB0092110003988_,2.93859431,0.579619498,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,buprenorphine,DB00921
,57356,DB00598,10013968,70,1518,41,987,0.621212371,1.110074921,0.737698715,1.688906417,0.761528748,DB0059810013968_,0.272427355,0.104427509,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,labetalol,DB00598
,57357,DB00921,10013968,111,5734,91,4812,0.886818431,1.023645845,0.766682605,1.369674736,0.95298528,DB0092110013968_,0.048155821,0.023370612,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,buprenorphine,DB00921
,57358,DB01098,10013968,353,7796,267,6942,0.048744251,1.177257053,0.998004708,1.389952901,0.122695009,DB0109810013968_,2.098053601,0.163187201,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,57359,DB00448,10017577,66,5079,26,3098,0.065713267,1.548288882,0.967492889,2.545958885,0.153655057,DB0044810017577_,1.873045078,0.437150374,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,57362,DB01098,10017577,119,8030,91,7118,0.297299655,1.159160631,0.873136381,1.543157849,0.463192545,DB0109810017577_,0.769612448,0.147696149,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,57365,DB00722,10028391,137,25266,94,25938,0.002922122,1.496190051,1.14171122,1.967857711,0.013226792,DB0072210028391_,4.325510819,0.402921911,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,57366,DB00758,10028391,42,8258,52,10022,1,0.980223602,0.636098174,1.502605532,1,DB0075810028391_,0,-0.019974568,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,clopidogrel,DB00758
,57368,DB00448,10028836,47,5098,10,3114,0.001393731,2.870570429,1.428907777,6.380900102,0.00723139,DB0044810028836_,4.929324065,1.054510766,female,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lansoprazole,DB00448
,57370,DB00722,10028836,93,25310,72,25960,0.07340836,1.324826685,0.963019285,1.828872944,0.167189909,DB0072210028836_,1.788624931,0.281281647,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,57371,DB00758,10028836,42,8258,34,10040,0.083437452,1.501807782,0.931859176,2.436393685,0.184159326,DB0075810028836_,1.691953992,0.40666957,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,clopidogrel,DB00758
,57380,DB00196,10028813,301,4782,138,3147,0.000523276,1.435344563,1.163395916,1.777822813,0.003205386,DB0019610028813_,5.742922676,0.361404934,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fluconazole,DB00196
,57382,DB00060,10016825,51,9457,12,2453,0.876314193,1.102375438,0.578699363,2.27517638,0.94707942,DB0006010016825_,0.054372325,0.09746734,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,interferon beta-1a,DB00060
,57384,DB00060,10049438,51,9457,20,2445,0.139166263,0.659299943,0.385352858,1.169828619,0.26863371,DB0006010049438_,1.314406501,-0.4165767,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,57385,DB00108,10049438,87,10107,40,3255,0.076945051,0.700487841,0.475344373,1.04802973,0.173070398,DB0010810049438_,1.754056841,-0.355978272,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,57388,DB01225,10013700,70,4974,19,4621,2.91628744234945e-07,3.42212971,2.033843738,6.028313127,4.77450111629743e-06,DB0122510013700_,12.25222107,1.23026308,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,enoxaparin,DB01225
,57389,DB01225,10015150,35,5009,27,4613,0.525367288,1.193791286,0.700843503,2.054127955,0.683424684,DB0122510015150_,0.38063882,0.177134197,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,enoxaparin,DB01225
,57396,DB00215,10001497,66,11037,49,5227,0.020858179,0.637904995,0.433480101,0.944351358,0.06388083,DB0021510001497_,2.750735955,-0.449565917,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,57397,DB00788,10001497,40,9316,19,5042,0.684054526,1.13938823,0.643890701,2.085257414,0.809052071,DB0078810001497_,0.211891999,0.130491478,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,naproxen,DB00788
,57398,DB01156,10001497,151,13471,90,6238,0.060367395,0.776966509,0.59344345,1.022007993,0.144113073,DB0115610001497_,1.937157059,-0.252358032,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,57425,DB00215,10005557,50,11053,20,5256,0.608413947,1.18878967,0.694248794,2.110560654,0.751034851,DB0021510005557_,0.286303222,0.172935705,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,citalopram,DB00215
,57426,DB00338,10005557,210,33464,176,22096,0.021618402,0.787860645,0.641277955,0.968842494,0.065760871,DB0033810005557_,2.721730279,-0.238434051,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,omeprazole,DB00338
,57427,DB00788,10005557,35,9321,19,5042,1,0.9964482,0.553952481,1.846134667,1,DB0078810005557_,0,-0.003558122,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,naproxen,DB00788
,57428,DB01075,10005557,69,19879,46,11051,0.380313928,0.833884348,0.565550723,1.239631062,0.550379981,DB0107510005557_,0.597146365,-0.181660558,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,diphenhydramine,DB01075
,57429,DB01156,10005557,45,13577,27,6301,0.310537948,0.773469533,0.46918407,1.297733501,0.477939512,DB0115610005557_,0.738271098,-0.256868999,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,bupropion,DB01156
,57438,DB00338,10013395,58,33616,45,22227,0.422050734,0.8522238,0.567209956,1.287724498,0.591122905,DB0033810013395_,0.525731322,-0.159906111,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,57441,DB01075,10014387,112,19836,79,11018,0.111733309,0.78750247,0.584616837,1.065085396,0.22866898,DB0107510014387_,1.475479825,-0.238888772,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,diphenhydramine,DB01075
,57442,DB00215,10016825,73,11030,13,5263,0.000447552,2.679266179,1.471778738,5.274543779,0.002815676,DB0021510016825_,5.872552787,0.985542943,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,citalopram,DB00215
,57443,DB00788,10016825,51,9305,27,5034,1,1.02188696,0.628054925,1.69715306,1,DB0078810016825_,0,0.021650879,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,naproxen,DB00788
,57444,DB01156,10016825,81,13541,18,6310,0.003270694,2.096897938,1.245591285,3.717745119,0.014512186,DB0115610016825_,4.232766547,0.74045908,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,bupropion,DB01156
,57445,DB01075,10019063,87,19861,44,11053,0.648466528,1.100395431,0.756645231,1.620625431,0.78342339,DB0107510019063_,0.244082001,0.095669598,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,57446,DB01156,10019063,78,13544,66,6262,0.000418427,0.546396644,0.388074003,0.771383961,0.002658533,DB0115610019063_,5.929980635,-0.604410113,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,57447,DB01075,10020772,303,19645,142,10955,0.090488769,1.189875656,0.970283771,1.464896249,0.196027303,DB0107510020772_,1.629501328,0.173848811,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,diphenhydramine,DB01075
,57464,DB01075,10028521,49,19899,33,11064,0.419818701,0.825603166,0.519995801,1.326048233,0.588733938,DB0107510028521_,0.529780916,-0.191641049,NA,10028521,Mydriasis,10015919,Eye disorders,Eye,diphenhydramine,DB01075
,57465,DB01156,10028521,55,13567,8,6320,0.000629128,3.202388552,1.515409405,7.788835903,0.003747677,DB0115610028521_,5.586618969,1.163896954,female,10028521,Mydriasis,10015919,Eye disorders,Eye,bupropion,DB01156
,57466,DB00316,10028622,47,65427,33,36920,0.35230745,0.803704887,0.504042778,1.29504803,0.522058678,DB0031610028622_,0.649975288,-0.218523134,NA,10028622,Myoclonus,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,57469,DB00316,10039020,91,65383,111,36842,5.9123462116584e-08,0.461948115,0.346103591,0.615237495,1.12300332251028e-06,DB0031610039020_,13.69950392,-0.772302699,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,57470,DB00338,10039020,62,33612,46,22226,0.556383094,0.891256382,0.598632507,1.335394666,0.709790799,DB0033810039020_,0.342785002,-0.115123146,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,57472,DB01075,10039020,34,19914,31,11066,0.05156893,0.609448055,0.363263186,1.026012086,0.127978976,DB0107510039020_,2.055889277,-0.49520156,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,57473,DB01156,10039020,36,13586,45,6283,1.08771303096484e-05,0.369988826,0.231641079,0.587175243,0.000116625,DB0115610039020_,9.056549757,-0.994282473,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,57474,DB00338,10040108,57,33617,11,22261,3.25210911192794e-05,3.431288492,1.780492338,7.258606995,0.000304748,DB0033810040108_,8.096026826,1.232935844,female,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,57476,DB00338,10040752,43,33631,24,22248,0.534846648,1.185209013,0.703061799,2.042653863,0.691405468,DB0033810040752_,0.369028843,0.169919141,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,omeprazole,DB00338
,57478,DB01075,10040752,49,19899,52,11045,0.001209714,0.523025775,0.346452682,0.788589684,0.006445677,DB0107510040752_,5.044345552,-0.648124534,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,57479,DB00338,10042464,68,33606,18,22254,0.000242431,2.501606165,1.470222971,4.471527511,0.001690043,DB0033810042464_,6.383001594,0.916932991,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,57480,DB00788,10043071,51,9305,25,5036,0.719571394,1.104080957,0.670633553,1.861962755,0.83448122,DB0078810043071_,0.180945041,0.099013275,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,naproxen,DB00788
,57484,DB01075,10043089,38,19910,20,11077,0.891713557,1.057074019,0.59948863,1.918414997,0.955005127,DB0107510043089_,0.04603857,0.055504732,NA,10043089,Tachypnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,57486,DB00338,10046555,53,33621,65,22207,0.000914359,0.538592038,0.367348236,0.786537631,0.005119045,DB0033810046555_,5.274787339,-0.618796881,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,57500,DB00316,10061422,82,65392,75,36878,0.002695722,0.616561976,0.445140112,0.855130482,0.012388678,DB0031610061422_,4.390972298,-0.483596433,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,57502,DB01156,10061422,32,13590,24,6304,0.084008494,0.618504742,0.352710644,1.098369594,0.185077803,DB0115610061422_,1.686978984,-0.48045042,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,57517,DB01224,10005750,47,8061,21,5896,0.064778214,1.636935164,0.958259328,2.886173899,0.152067103,DB0122410005750_,1.883433386,0.492825691,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,quetiapine,DB01224
,57521,DB08910,10044034,65,16679,86,17402,0.165398831,0.788583929,0.561997366,1.101890817,0.304656884,DB0891010044034_,1.188569107,-0.237516437,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,57524,DB00627,10013700,246,1083,97,1502,1.61356877112336e-25,3.515762803,2.731031067,4.553016807,2.57046394842289e-23,DB0062710013700_,52.01537073,1.257256515,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,niacin,DB00627
,57526,DB00916,10029350,62,5261,73,2358,5.18726520144023e-08,0.380718232,0.265963078,0.543553997,9.99979947340349e-07,DB0091610029350_,13.81553061,-0.965695725,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,metronidazole,DB00916
,57530,DB09020,10013709,63,1891,38,1566,0.129510845,1.37283542,0.898141154,2.12314926,0.254938408,DB0902010013709_,1.366733301,0.316878251,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,bisacodyl,DB09020
,57542,DB00916,10053762,120,5203,79,2352,0.013023279,0.686680186,0.510348781,0.928159311,0.043945938,DB0091610053762_,3.124795089,-0.375886618,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,metronidazole,DB00916
,57543,DB09020,10053762,44,1910,31,1573,0.558462979,1.168872819,0.7177681,1.924540848,0.711384921,DB0902010053762_,0.340541616,0.156039882,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,bisacodyl,DB09020
,57550,DB00559,10035759,31,9628,22,3284,0.010836644,0.480641351,0.269052025,0.872573867,0.037963639,DB0055910035759_,3.271126438,-0.732633919,NA,10035759,Pneumothorax,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,57556,DB00374,10040753,209,17507,39,5685,0.001033516,1.740092213,1.229782902,2.519934138,0.005661344,DB0037410040753_,5.174093919,0.553938108,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,treprostinil,DB00374
,57557,DB06403,10040753,289,21182,50,6611,6.21007223936889e-05,1.803855964,1.330418767,2.490323933,0.000530749,DB0640310040753_,7.541221992,0.589926576,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,57558,DB06403,10047700,881,20590,164,6497,1.21214950514215e-10,1.694959285,1.42968898,2.019819032,3.88790112784155e-09,DB0640310047700_,19.36539638,0.52765872,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,57562,DB00335,10000059,116,8350,63,5402,0.281395533,1.191155126,0.867339893,1.648912375,0.445341342,DB0033510000059_,0.80891423,0.17492353,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,57563,DB00425,10000059,151,12544,69,7415,0.079586924,1.293592821,0.965241983,1.748369765,0.177742666,DB0042510000059_,1.72741847,0.257423479,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,57565,DB00959,10000059,79,7999,34,4968,0.080098953,1.443053184,0.952254647,2.229026461,0.178552431,DB0095910000059_,1.72287299,0.366761135,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,57566,DB01104,10000059,189,15274,73,7213,0.161854638,1.222614814,0.927070864,1.627015001,0.299876589,DB0110410000059_,1.204384258,0.200991856,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,57567,DB01611,10000059,232,11681,37,2324,0.245796285,1.247485883,0.876055819,1.821475875,0.404695155,DB0161110000059_,0.904621198,0.221130232,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,57568,DB06273,10000059,61,5034,6,1404,0.010406943,2.835253768,1.226640617,8.043365207,0.036734907,DB0627310000059_,3.304027832,1.042131446,female,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,tocilizumab,DB06273
,57569,DB00425,10000087,161,12534,55,7429,0.000292774,1.734972265,1.268196111,2.404593705,0.001978546,DB0042510000087_,6.225393155,0.550991428,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,57571,DB00959,10000087,67,8011,39,4963,0.841060709,1.0643113,0.705517236,1.625264052,0.918820335,DB0095910000087_,0.084664676,0.062327923,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,57572,DB01611,10000087,122,11791,13,2348,0.026989438,1.868726248,1.050668107,3.616028756,0.077992236,DB0161110000087_,2.551145999,0.625257048,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,57575,DB00959,10047895,115,7963,96,4906,0.032020429,0.738070384,0.55659997,0.980484409,0.089149134,DB0095910047895_,2.417444647,-0.303716088,NA,10047895,Weight decreased,10022891,Investigations,Inv,methylprednisolone,DB00959
,57576,DB06273,10047895,30,5065,22,1388,0.000978646,0.37378365,0.207742449,0.682344355,0.005409866,DB0627310047895_,5.219531007,-0.984078125,NA,10047895,Weight decreased,10022891,Investigations,Inv,tocilizumab,DB06273
,57577,DB00158,10061428,232,16583,142,7962,0.026014392,0.784471191,0.632733247,0.975291341,0.075745033,DB0015810061428_,2.580382404,-0.24274543,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,folic acid,DB00158
,57579,DB00959,10061428,84,7994,65,4937,0.175896566,0.798138459,0.569295834,1.123167504,0.318517533,DB0095910061428_,1.144077757,-0.225473189,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,methylprednisolone,DB00959
,57581,DB00559,10028596,75,9584,24,3282,0.818068163,1.07013711,0.666684554,1.775675844,0.902877127,DB0055910028596_,0.102168806,0.06778678,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,bosentan,DB00559
,57582,DB00028,10008190,45,13413,38,5577,0.001592726,0.492387315,0.312246106,0.780254759,0.008067992,DB0002810008190_,4.819850661,-0.708489646,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,57583,DB00273,10008190,55,8426,15,2178,0.881918302,0.947779148,0.526679478,1.809997609,0.950599903,DB0027310008190_,0.050662017,-0.05363377,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,57585,DB00343,10008190,107,8629,46,5049,0.091619616,1.361010716,0.952982062,1.970659339,0.197854918,DB0034310008190_,1.620221255,0.308227597,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,57589,DB00668,10008190,35,10056,27,4276,0.025211231,0.55126048,0.323741994,0.948170708,0.073971893,DB0066810008190_,2.604070076,-0.59554784,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,epinephrine,DB00668
,57590,DB00697,10008190,51,6045,14,1792,0.882870665,1.079890175,0.587105582,2.117721924,0.951043643,DB0069710008190_,0.050195326,0.076859346,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,57591,DB00727,10008190,66,3777,48,4125,0.03743095,1.501599982,1.016876179,2.23172432,0.100441276,DB0072710008190_,2.29818204,0.406531194,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,57592,DB01050,10008190,128,17980,68,9303,0.879878358,0.973925926,0.719406092,1.328463607,0.949545405,DB0105010008190_,0.05177193,-0.02642003,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,57593,DB01068,10008190,85,13678,30,6810,0.112442239,1.410637271,0.919456453,2.218628167,0.229753129,DB0106810008190_,1.4707499,0.344041568,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,57594,DB01222,10008190,56,9218,38,5367,0.519938284,0.858038535,0.557480071,1.333480464,0.679101484,DB0122210008190_,0.386984702,-0.153106268,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,57595,DB01224,10008190,56,8052,30,5887,0.18911778,1.36473179,0.859720827,2.205838554,0.335422459,DB0122410008190_,1.092364471,0.310957919,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,57596,DB09140,10008190,36,3705,24,1774,0.214138349,0.718242933,0.415421708,1.262638488,0.366447038,DB0914010008190_,1.003901275,-0.33094742,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,oxygen,DB09140
,57597,DB09153,10008190,49,7750,41,5658,0.522580168,0.872527088,0.563592592,1.356979435,0.681079914,DB0915310008190_,0.384075631,-0.136361579,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,57600,DB01076,10039020,92,25655,226,25357,1.94330112597536e-14,0.402339999,0.312043774,0.515269783,1.09730762827631e-12,DB0107610039020_,27.53816155,-0.91045778,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,57604,DB01164,10053762,66,6458,27,7909,5.37941204826334e-07,2.993450789,1.883832128,4.880260247,8.28583918479941e-06,DB0116410053762_,11.70096262,1.096426832,female,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium chloride,DB01164
,57605,DB01224,10019063,173,7935,332,5585,2.18174857984124e-27,0.366787396,0.302424945,0.443591135,4.03769896972695e-25,DB0122410019063_,56.16895236,-1.002972902,male,10019063,Hallucination,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,57607,DB01224,10019075,33,8075,42,5875,0.018576123,0.571685758,0.350600368,0.925061937,0.058294339,DB0122410019075_,2.842250283,-0.559165812,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,57613,DB01224,10029412,38,8070,29,5888,0.901543766,0.956023258,0.573478977,1.609324105,0.957032345,DB0122410029412_,0.04391809,-0.044973038,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,57614,DB01224,10019070,29,8079,30,5887,0.187995535,0.704419044,0.407455256,1.216041735,0.334030829,DB0122410019070_,1.096521988,-0.350381867,NA,10019070,"Hallucination, auditory",10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,57615,DB01224,10013950,57,8051,29,5888,0.12520571,1.437419465,0.902627192,2.334642761,0.2488767,DB0122410013950_,1.390797685,0.362849468,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,quetiapine,DB01224
,57617,DB00425,10019063,61,12634,47,7437,0.193819851,0.764019033,0.513111127,1.143826496,0.34146954,DB0042510019063_,1.0744968,-0.269162578,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,57622,DB00012,10015090,42,1604,14,1299,0.003948645,2.428826754,1.293473208,4.83750812,0.016898426,DB0001210015090_,4.080534792,0.887408323,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,darbepoetin alfa,DB00012
,57636,DB00559,10064687,139,9520,44,3262,0.732610699,1.082446159,0.764165915,1.559840182,0.844702031,DB0055910064687_,0.168771339,0.079223442,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,bosentan,DB00559
,57639,DB00005,10065048,68,128014,31,42388,0.161974646,0.726329483,0.468339519,1.149621799,0.300035487,DB0000510065048_,1.203854522,-0.319751533,NA,10065048,Latent tuberculosis,10021881,Infections and infestations,Infec,etanercept,DB00005
,57640,DB00005,10002544,129,127953,20,42399,0.000835112,2.137150665,1.328005865,3.615926371,0.004744603,DB0000510002544_,5.350747436,0.759473477,NA,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,57649,DB00795,10016173,47,4522,19,1484,0.473193894,0.81181294,0.465654698,1.469707419,0.639168733,DB0079510016173_,0.447586802,-0.208485335,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sulfasalazine,DB00795
,57650,DB01409,10016173,181,5850,108,3858,0.428358791,1.105263808,0.86291483,1.42107703,0.596904566,DB0140910016173_,0.515998034,0.100084047,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,tiotropium,DB01409
,57652,DB01222,10050584,101,9173,22,5383,5.19956647240828e-06,2.693920833,1.683579262,4.494087522,6.12460697859071e-05,DB0122210050584_,9.700610877,0.990997691,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,budesonide,DB01222
,57653,DB01409,10050584,63,5968,22,3944,0.010050321,1.892340577,1.146257368,3.23525866,0.035711542,DB0140910050584_,3.332281342,0.637814463,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,tiotropium,DB01409
,57654,DB00005,10015946,86,127996,30,42389,0.829890597,0.949362782,0.619871413,1.490843774,0.910731198,DB0000510015946_,0.093507487,-0.051964275,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,etanercept,DB00005
,57659,DB00437,10000087,83,6838,87,11459,0.002453897,1.598625141,1.167197213,2.188351374,0.011497447,DB0043710000087_,4.465630255,0.469143973,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,57661,DB00581,10000087,38,2075,29,2040,0.326340755,1.288161701,0.770410291,2.174621598,0.494857894,DB0058110000087_,0.70348464,0.253216164,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,lactulose,DB00581
,57665,DB00761,10000087,202,15105,65,8560,4.95045994557884e-05,1.761089187,1.323694956,2.369552149,0.000437977,DB0076110000087_,7.733345137,0.565932474,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,57666,DB00836,10000087,93,5442,36,4039,0.000837995,1.917190545,1.288807088,2.907217034,0.004757387,DB0083610000087_,5.348056705,0.650860857,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,57671,DB00658,10002034,33,1270,29,1367,0.443363944,1.224748757,0.716402926,2.104113021,0.61152444,DB0065810002034_,0.491800357,0.202735727,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,sevelamer,DB00658
,57674,DB00836,10002034,127,5408,77,3998,0.197333407,1.21929863,0.90864778,1.64502083,0.34578238,DB0083610002034_,1.061945662,0.1982758,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,loperamide,DB00836
,57699,DB00186,10013916,52,16849,28,9980,0.729325399,1.100032689,0.681528828,1.81022351,0.842281112,DB0018610013916_,0.171641458,0.095339897,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,57708,DB00695,10013916,61,27988,22,20506,0.003637584,2.031454651,1.229203477,3.475242525,0.015802642,DB0069510013916_,4.147578156,0.708752113,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,57712,DB00904,10013916,48,23021,18,14438,0.07549627,1.672420835,0.954714621,3.056291435,0.170636695,DB0090410013916_,1.768218571,0.514272178,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,57722,DB00316,10014380,32,65442,22,36931,0.480996369,0.820858545,0.462300687,1.482959261,0.64564165,DB0031610014380_,0.43751065,-0.19740448,NA,10014380,Electrocardiogram QRS complex prolonged,10022891,Investigations,Inv,acetaminophen,DB00316
,57733,DB00836,10014380,35,5500,74,4001,8.07875507751745e-08,0.344103639,0.222853184,0.52230926,1.49017598043892e-06,DB0083610014380_,13.41661634,-1.06681239,male,10014380,Electrocardiogram QRS complex prolonged,10022891,Investigations,Inv,loperamide,DB00836
,57739,DB00169,10020642,300,38391,94,18081,0.000504105,1.503084921,1.187614116,1.917084599,0.00311115,DB0016910020642_,5.772762769,0.40751961,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,57740,DB00213,10020642,143,18752,92,13329,0.465865304,1.104859896,0.843476204,1.453239594,0.632666986,DB0021310020642_,0.457811083,0.099718536,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,57743,DB00437,10020642,30,6891,60,11486,0.446399478,0.833444398,0.51843198,1.314077055,0.614212593,DB0043710020642_,0.487414168,-0.182188288,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,57748,DB00761,10020642,117,15190,44,8581,0.021028238,1.502125716,1.052494254,2.177985374,0.064315843,DB0076110020642_,2.743949284,0.406881249,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,potassium chloride,DB00761
,57749,DB00904,10020642,156,22913,99,14357,0.948543743,0.987346959,0.7619702,1.284485037,0.986955597,DB0090410020642_,0.013130229,-0.012733773,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,57753,DB00186,10024855,132,16769,60,9948,0.099001513,1.305110015,0.953806767,1.803544246,0.209361179,DB0018610024855_,1.563694391,0.26628734,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,57754,DB00213,10024855,141,18754,86,13335,0.279832734,1.165756438,0.884457867,1.544132268,0.443678105,DB0021310024855_,0.812655968,0.153370179,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,57756,DB00295,10024855,103,14560,52,9550,0.137955942,1.29918549,0.921067262,1.851919706,0.266855939,DB0029510024855_,1.321046321,0.261737522,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,morphine,DB00295
,57758,DB00437,10024855,48,6873,72,11474,0.571316459,1.112944812,0.754917975,1.628028891,0.72156175,DB0043710024855_,0.326337319,0.107009487,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,57764,DB00761,10024855,126,15181,63,8562,0.44824326,1.128001497,0.826134348,1.553470619,0.615975642,DB0076110024855_,0.484547859,0.12044748,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,57765,DB00836,10024855,54,5481,31,4044,0.321138206,1.285203893,0.809867585,2.07239619,0.489439466,DB0083610024855_,0.714494489,0.250917378,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,57766,DB00904,10024855,170,22899,97,14359,0.487834487,1.09898113,0.850623469,1.426511249,0.651528352,DB0090410024855_,0.428434365,0.094383505,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,57770,DB11089,10024855,68,10107,71,8336,0.17180702,0.789939431,0.55723995,1.11898761,0.313183363,DB1108910024855_,1.160966434,-0.235799006,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,docusate,DB11089
,57772,DB00213,10027141,50,18845,47,13374,0.18004736,0.75499926,0.496431629,1.149897349,0.32389418,DB0021310027141_,1.127338421,-0.28103851,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,57774,DB00316,10027141,63,65411,44,36909,0.313752607,0.80793606,0.540947585,1.216074226,0.481238681,DB0031610027141_,0.731391914,-0.213272357,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,57794,DB00904,10028596,86,22983,83,14373,0.005445101,0.648009132,0.473289446,0.887561544,0.021896195,DB0090410028596_,3.821442393,-0.43385049,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,ondansetron,DB00904
,57799,DB00437,10033557,50,6871,34,11512,5.8412085329768e-05,2.463783201,1.560472128,3.932573447,0.000504224,DB0043710033557_,7.592490216,0.901698055,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,allopurinol,DB00437
,57805,DB00761,10033557,194,15113,47,8578,2.33286937083056e-08,2.342745851,1.693783404,3.298419667,4.81881897149558e-07,DB0076110033557_,14.54556678,0.851323682,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,57806,DB00836,10033557,44,5491,17,4058,0.026346758,1.912644789,1.069143264,3.5758845,0.076525396,DB0083610033557_,2.570132618,0.648486991,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,loperamide,DB00836
,57807,DB00904,10033557,180,22889,48,14408,2.22870235775401e-08,2.360466172,1.707043594,3.31950165,4.62363389688745e-07,DB0090410033557_,14.5869147,0.85885913,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,ondansetron,DB00904
,57811,DB11089,10033557,78,10097,18,8389,7.67299511015312e-08,3.599997908,2.133777736,6.393895171,1.42506822957896e-06,DB1108910033557_,13.46129086,1.280933264,female,10033557,Palpitations,10007541,Cardiac disorders,Card,docusate,DB11089
,57812,DB00169,10033645,85,38606,53,18122,0.119825419,0.752803434,0.527778488,1.0824355,0.241130996,DB0016910033645_,1.422414943,-0.283951129,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,57813,DB00186,10033645,61,16840,45,9963,0.269052929,0.802001575,0.536273712,1.207294421,0.431565035,DB0018610033645_,0.84033706,-0.220644707,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,57814,DB00213,10033645,89,18806,66,13355,0.806684371,0.957594149,0.688109878,1.338399006,0.895526273,DB0021310033645_,0.110343719,-0.043331235,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,57816,DB00295,10033645,38,14625,29,9573,0.534163863,0.857714092,0.514767358,1.443040174,0.690799367,DB0029510033645_,0.36990585,-0.153484462,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,57824,DB00987,10033645,17,2087,43,2885,0.035149585,0.546580963,0.291405125,0.98172183,0.095721804,DB0098710033645_,2.346309173,-0.604072834,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,cytarabine,DB00987
,57827,DB00169,10033661,129,38562,109,18066,9.84711325065891e-06,0.55449054,0.426041789,0.722681598,0.000107132,DB0016910033661_,9.141447063,-0.589705532,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,57828,DB00213,10033661,108,18787,107,13314,0.015031104,0.71532409,0.541893216,0.944371011,0.049398921,DB0021310033661_,3.0078267,-0.335019566,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,pantoprazole,DB00213
,57829,DB00437,10033661,92,6829,125,11421,0.138653167,1.230876698,0.928364134,1.627052065,0.267872914,DB0043710033661_,1.317242611,0.207726678,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,allopurinol,DB00437
,57832,DB00836,10033661,42,5493,36,4039,0.565447972,0.857865834,0.535450576,1.380842291,0.717022454,DB0083610033661_,0.332648122,-0.153307562,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,loperamide,DB00836
,57838,DB00836,10035528,85,5450,53,4022,0.385718604,1.183525109,0.827941116,1.705181537,0.555845039,DB0083610035528_,0.58726573,0.168497366,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,loperamide,DB00836
,57841,DB00169,10036653,72,38619,43,18132,0.229586541,0.786186061,0.531290897,1.17572427,0.385430302,DB0016910036653_,0.953394901,-0.240561796,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,57842,DB00213,10036653,50,18845,30,13391,0.497079553,1.184284115,0.738107959,1.930195777,0.65921978,DB0021310036653_,0.416698295,0.16913847,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,57853,DB00761,10036653,65,15242,18,8607,0.005802776,2.03910116,1.193965803,3.655388732,0.023052364,DB0076110036653_,3.769986969,0.712509103,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,57855,DB00904,10036653,58,23011,22,14434,0.049964707,1.653676847,0.996222099,2.838826841,0.124929591,DB0090410036653_,2.080004969,0.503001201,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,57861,DB00497,10045555,112,19155,169,16206,1.81269914873666e-06,0.560709041,0.437166087,0.716847926,2.42910003184007e-05,DB0049710045555_,10.62540463,-0.578553152,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,57863,DB00904,10045555,79,22990,68,14388,0.061431827,0.727099109,0.518705957,1.021503584,0.146096863,DB0090410045555_,1.923485434,-0.318692485,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,57874,DB00695,10046274,69,27980,96,20432,4.94916855631373e-05,0.524875106,0.379334158,0.723040768,0.000437936,DB0069510046274_,7.733437725,-0.644594938,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,57880,DB00374,10008469,407,17309,92,5632,0.00154333,1.439398475,1.142912471,1.828941219,0.007875448,DB0037410008469_,4.844005234,0.3642253,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,57913,DB00996,10011224,586,38367,249,22176,4.23850763220838e-05,1.360258678,1.169679777,1.585504932,0.000383574,DB0099610011224_,7.865977055,0.307674886,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,57914,DB00181,10012174,90,9766,40,5831,0.122797469,1.343386481,0.91448678,2.004541587,0.24540821,DB0018110012174_,1.404832293,0.29519365,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,baclofen,DB00181
,57915,DB08868,10012174,60,9142,13,2498,0.5668013,1.261100124,0.683268188,2.508397314,0.71809766,DB0886810012174_,0.331149702,0.231984454,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,fingolimod,DB08868
,57918,DB00169,10025256,118,38573,33,18142,0.006715769,1.681768361,1.134373493,2.556025701,0.025921292,DB0016910025256_,3.65269057,0.519845836,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,57919,DB00186,10025256,42,16859,27,9981,0.803214828,0.920936456,0.554285613,1.554266711,0.8934756,DB0018610025256_,0.112636254,-0.08236424,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,lorazepam,DB00186
,57920,DB00338,10025256,54,33620,33,22239,0.743764529,1.082435992,0.689027507,1.723828169,0.853537542,DB0033810025256_,0.158365751,0.079214049,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,omeprazole,DB00338
,57925,DB00996,10025256,82,38871,17,22408,3.60354251845217e-05,2.780574202,1.634752797,5.002982458,0.000333401,DB0099610025256_,8.006165739,1.022657454,female,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,gabapentin,DB00996
,57929,DB00046,10040047,83,5376,100,4592,0.02457072,0.708988647,0.52202979,0.960809179,0.072550143,DB0004610040047_,2.62347733,-0.343915766,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,insulin lispro,DB00046
,57930,DB00047,10040047,116,9169,118,8400,0.430133826,0.900608591,0.689681347,1.17581498,0.598600536,DB0004710040047_,0.513160789,-0.104684532,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,57931,DB00181,10040047,125,9731,104,5767,0.013063767,0.712348014,0.543555307,0.935058841,0.044057111,DB0018110040047_,3.122268507,-0.339188703,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,baclofen,DB00181
,57932,DB00381,10040047,254,29106,262,22625,0.001525584,0.753606785,0.631069754,0.899812667,0.007799278,DB0038110040047_,4.853724177,-0.282884552,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,amlodipine,DB00381
,57933,DB00476,10040047,131,17126,61,6116,0.099555023,0.766934471,0.560984175,1.058578005,0.210122961,DB0047610040047_,1.56006239,-0.265353917,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,duloxetine,DB00476
,57935,DB01224,10040047,42,8066,45,5872,0.081160876,0.679492403,0.434766902,1.059999088,0.180353689,DB0122410040047_,1.712835416,-0.386409225,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,quetiapine,DB01224
,57939,DB00047,10046571,237,9048,81,8437,1.81487314719822e-16,2.727980533,2.10745013,3.562326073,1.32143879983671e-14,DB0004710046571_,31.95747016,1.003561604,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,57940,DB00476,10046571,401,16856,79,6098,2.51805091680124e-07,1.836328991,1.436716323,2.372363724,4.17460468939353e-06,DB0047610046571_,12.38649089,0.607768465,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,duloxetine,DB00476
,57942,DB01224,10046571,142,7966,58,5859,0.000123267,1.800628811,1.315149837,2.492850916,0.000953522,DB0122410046571_,6.955348305,0.588135944,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,quetiapine,DB01224
,57943,DB01591,10046571,82,1873,13,643,0.007737867,2.164931583,1.188261862,4.267256993,0.029012171,DB0159110046571_,3.540039837,0.77238876,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,solifenacin,DB01591
,57944,DB04861,10046571,56,1909,7,1380,1.81982635424326e-07,5.780902872,2.617784267,15.08800441,3.11521561193645e-06,DB0486110046571_,12.67921219,1.754559877,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,nebivolol,DB04861
,57947,DB00169,10059570,75,38616,37,18138,0.839358132,0.952099377,0.633754614,1.452910736,0.917718939,DB0016910059570_,0.085864101,-0.049085862,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,57949,DB00186,10059570,43,16858,24,9984,0.899530606,1.061101919,0.629199819,1.829183828,0.956517739,DB0018610059570_,0.044455945,0.059307915,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,lorazepam,DB00186
,57950,DB00338,10059570,56,33618,49,22223,0.16264964,0.755495393,0.505447333,1.13248298,0.300925304,DB0033810059570_,1.200893206,-0.280381596,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,omeprazole,DB00338
,57951,DB00381,10059570,36,29324,30,22857,0.804875498,0.935368957,0.559938946,1.572884088,0.894427482,DB0038110059570_,0.11157145,-0.066814221,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,amlodipine,DB00381
,57953,DB00996,10059570,58,38895,28,22397,0.501901941,1.192760774,0.747178352,1.945859543,0.6632893,DB0099610059570_,0.410544035,0.176270598,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,gabapentin,DB00996
,57956,DB09037,10003549,63,2463,98,2737,0.044811712,0.714418966,0.509645788,0.995401443,0.115223853,DB0903710003549_,2.160878494,-0.336285702,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pembrolizumab,DB09037
,57958,DB01234,10011781,88,31537,34,32854,2.53654114159407e-07,2.696336873,1.795365793,4.133611571,4.19987300200316e-06,DB0123410011781_,12.38045627,0.991894138,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,57960,DB09037,10013968,87,2439,136,2699,0.013615791,0.707946478,0.531533206,0.938883334,0.045524527,DB0903710013968_,3.089504041,-0.345386784,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pembrolizumab,DB09037
,57961,DB01202,10037377,30,6684,22,5696,0.676343454,1.162055074,0.647447476,2.116782206,0.80384645,DB0120210037377_,0.21834701,0.150190053,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levetiracetam,DB01202
,57962,DB09037,10037377,31,2495,27,2808,0.356294981,1.292116557,0.743970585,2.256867034,0.525973074,DB0903710037377_,0.642505258,0.256281616,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pembrolizumab,DB09037
,57964,DB00982,10013786,138,3226,118,1983,0.012258405,0.718942145,0.554509527,0.933302591,0.041866521,DB0098210013786_,3.173268801,-0.32997439,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,isotretinoin,DB00982
,57967,DB00425,10029412,30,12665,30,7454,0.044334326,0.588594345,0.342503977,1.011422486,0.114275828,DB0042510029412_,2.169140208,-0.53001805,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,57968,DB00068,10003549,74,2160,22,643,1,1.001304288,0.609239809,1.707165576,1,DB0006810003549_,0,0.001303439,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,57971,DB00068,10037660,95,2139,27,638,0.912521553,1.049420399,0.671225023,1.690178511,0.960726604,DB0006810037660_,0.040065401,0.048238011,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,57980,DB06403,10042674,579,20892,147,6514,0.027017373,1.228071332,1.020712515,1.485251347,0.078058788,DB0640310042674_,2.550293038,0.205444916,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,57984,DB00334,10010305,72,2777,91,2721,0.112648775,0.775290793,0.558445107,1.073047778,0.230067836,DB0033410010305_,1.469381075,-0.254517103,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,57985,DB00334,10016173,77,2772,60,2752,0.167460003,1.274016527,0.893314529,1.824337628,0.307466205,DB0033410016173_,1.179390102,0.24217453,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,olanzapine,DB00334
,57990,DB00374,10037569,46,17670,6,5718,0.03420119,2.480969036,1.056104101,7.112207757,0.093812057,DB0037410037569_,2.366461894,0.908649224,NA,10037569,Purulent discharge,10021881,Infections and infestations,Infec,treprostinil,DB00374
,57996,DB00567,10013573,126,4393,50,2031,0.411028141,1.165024651,0.82944071,1.657975969,0.580369836,DB0056710013573_,0.544089731,0.152742247,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,cephalexin,DB00567
,57997,DB01068,10013573,488,13275,219,6621,0.207925448,1.111391268,0.94299582,1.313109507,0.358754496,DB0106810013573_,1.025116979,0.105612625,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,57998,DB00254,10016322,60,5875,30,3358,0.583636417,1.14315578,0.724152241,1.839692229,0.731580782,DB0025410016322_,0.312547631,0.133792666,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,57999,DB00422,10016322,108,3327,64,2885,0.019781222,1.463221953,1.059688619,2.034407738,0.061271437,DB0042210016322_,2.792441497,0.380640822,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,58000,DB00567,10016322,50,4469,22,2059,0.899318253,1.047104875,0.620588526,1.820900265,0.956490275,DB0056710016322_,0.044484657,0.046029094,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,58001,DB00745,10016322,72,2505,29,1054,0.912204014,1.044617544,0.665619891,1.678271626,0.960594091,DB0074510016322_,0.040203341,0.043650832,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,modafinil,DB00745
,58002,DB06637,10016322,97,6065,19,2000,0.038902518,1.683347845,1.019007825,2.923745744,0.10343442,DB0663710016322_,2.26881749,0.520784575,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,58010,DB00215,10028372,80,11023,28,5248,0.179520743,1.360283301,0.873419136,2.176125412,0.323260127,DB0021510028372_,1.129297932,0.307692987,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,58012,DB00567,10028372,36,4483,17,2064,1,0.974980525,0.532197794,1.855592088,1,DB0056710028372_,0,-0.025337783,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,cephalexin,DB00567
,58013,DB00745,10028372,48,2529,21,1062,0.894296234,0.959846449,0.560555802,1.696493197,0.95590161,DB0074510028372_,0.045100289,-0.040981957,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,modafinil,DB00745
,58014,DB01068,10028372,131,13632,70,6770,0.651658396,0.929404067,0.689022313,1.262686909,0.78603313,DB0106810028372_,0.240756337,-0.073211687,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,58023,DB01076,10037087,531,25216,336,25247,4.09329125812921e-11,1.582276181,1.375992904,1.821417451,1.4241186064848e-09,DB0107610037087_,20.36971274,0.458864431,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,58025,DB01137,10001760,71,7701,12,5581,1.26332735357488e-07,4.28747767,2.305281815,8.694935647,2.24900504495196e-06,DB0113710001760_,13.00502264,1.455698604,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,levofloxacin,DB01137
,58030,DB00374,10061623,47,17669,17,5707,0.663837484,0.892976954,0.502880387,1.66033755,0.795249562,DB0037410061623_,0.229099299,-0.113194506,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,58031,DB00820,10061623,35,11880,24,5792,0.211816844,0.710992101,0.410641119,1.250654533,0.363598742,DB0082010061623_,1.011704376,-0.341093959,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,58036,DB00999,10008531,208,21222,69,12170,5.52634843846806e-05,1.728668489,1.309358743,2.306183881,0.000480994,DB0099910008531_,7.639656583,0.547351452,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,58038,DB01136,10008531,55,9829,65,11050,0.854573994,0.951256727,0.651264496,1.385132901,0.929372864,DB0113610008531_,0.07324526,-0.049971298,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,58040,DB01136,10033371,281,9603,188,10927,2.19331565072384e-08,1.700695612,1.405899436,2.061023004,4.56102071829717e-07,DB0113610033371_,14.60054921,0.531037351,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,58042,DB01118,10037660,32,3031,59,4650,0.450700354,0.832118806,0.522201567,1.304242695,0.618398434,DB0111810037660_,0.480622313,-0.183780052,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,58044,DB00999,10044565,221,21209,89,12150,0.005220917,1.422505542,1.106140902,1.842498407,0.021179381,DB0099910044565_,3.854727178,0.352419783,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,58045,DB01118,10044565,39,3024,41,4668,0.106755167,1.468236401,0.920052789,2.339861259,0.22125445,DB0111810044565_,1.508441883,0.384061953,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,amiodarone,DB01118
,58046,DB01136,10044565,75,9809,69,11046,0.241269228,1.224015894,0.869757987,1.724816478,0.399405185,DB0113610044565_,0.917778876,0.202137169,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,58048,DB01015,10073508,76,9811,121,9260,0.000328023,0.592844932,0.438364365,0.7975232,0.002171536,DB0101510073508_,6.13232032,-0.522822411,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,58051,DB00047,10033557,82,9203,25,8493,2.61243006986827e-07,3.026543791,1.911925023,4.949735058,4.31680102562063e-06,DB0004710033557_,12.35299593,1.107421306,female,10033557,Palpitations,10007541,Cardiac disorders,Card,insulin glargine,DB00047
,58052,DB01222,10033557,84,9190,23,5382,0.000825587,2.13874541,1.333282304,3.560008588,0.00469985,DB0122210033557_,5.360224754,0.7602194,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,budesonide,DB01222
,58054,DB06724,10013573,274,7655,114,3805,0.124466771,1.19464847,0.953301223,1.504997294,0.247764708,DB0672410013573_,1.395275741,0.177851974,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,58055,DB00370,10019211,143,4398,69,3594,0.000337834,1.693487112,1.257374338,2.299095596,0.002226668,DB0037010019211_,6.107248773,0.526789783,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,mirtazapine,DB00370
,58056,DB00612,10019211,47,1093,7,633,0.00023851,3.886233811,1.731652244,10.25350434,0.001669122,DB0061210019211_,6.395457501,1.357440517,female,10019211,Headache,10029205,Nervous system disorders,Nerv,bisoprolol,DB00612
,58057,DB00186,10039101,86,16815,25,9983,0.001102032,2.042262786,1.294365232,3.330578968,0.005963729,DB0018610039101_,5.122059362,0.714058402,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,58061,DB00421,10039101,77,8826,13,5239,2.76964965209751e-06,3.515607324,1.936981785,6.907832552,3.52885318009613e-05,DB0042110039101_,10.25195252,1.257212291,female,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,58062,DB00425,10039101,54,12641,27,7457,0.564677593,1.179837641,0.729567468,1.94988507,0.716402216,DB0042510039101_,0.333513516,0.165376837,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,58063,DB00448,10039101,37,5108,16,3108,0.319712039,1.407001898,0.762146963,2.713857019,0.487866278,DB0044810039101_,0.71771393,0.341461127,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lansoprazole,DB00448
,58066,DB01050,10039101,84,18024,31,9340,0.114925678,1.404132869,0.919248176,2.195549829,0.233525439,DB0105010039101_,1.454464263,0.339419937,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,58067,DB08895,10039101,370,27744,62,6584,0.011443173,1.416199854,1.07816266,1.887122504,0.039662928,DB0889510039101_,3.227338334,0.347977125,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,58069,DB00005,10018884,97,127985,31,42388,0.918805742,1.036339311,0.685223914,1.607379074,0.964146885,DB0000510018884_,0.036511626,0.035694611,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,etanercept,DB00005
,58070,DB00005,10038695,39,128043,12,42407,1,1.076377835,0.552096781,2.25823686,1,DB0000510038695_,0,0.073601548,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,58072,DB00698,10013700,518,2630,23,406,3.5031713515604e-11,3.47601854,2.255599407,5.605256701,1.23350112492652e-09,DB0069810013700_,20.51340927,1.245887541,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,nitrofurantoin,DB00698
,58078,DB00005,10052897,78,128004,31,42388,0.377042465,0.833181789,0.54300459,1.307521572,0.546955556,DB0000510052897_,0.60338773,-0.182503427,NA,10052897,Nerve injury,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,58079,DB00959,10020635,66,8012,54,4948,0.131604315,0.754843947,0.517845978,1.104413652,0.258039782,DB0095910020635_,1.354641512,-0.281244244,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,methylprednisolone,DB00959
,58080,DB00959,10028411,101,7977,28,4974,7.75355499199199e-05,2.249077578,1.464864135,3.557077123,0.000640887,DB0095910028411_,7.352656781,0.810520167,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,methylprednisolone,DB00959
,58083,DB00331,10013082,67,24879,41,20711,0.122735592,1.360365214,0.908412285,2.059326085,0.245326313,DB0033110013082_,1.405166065,0.307753203,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,58084,DB00331,10013911,143,24803,118,20634,1,1.008168917,0.783964573,1.298540332,1,DB0033110013911_,0,0.008135732,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,metformin,DB00331
,58085,DB00331,10042674,157,24789,86,20666,0.001872586,1.521926551,1.161883006,2.004802017,0.009220853,DB0033110042674_,4.686287681,0.419977,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,58095,DB00051,10042128,109,25622,25,11395,0.001888972,1.939014425,1.245638603,3.128438862,0.009285448,DB0005110042128_,4.679306785,0.662179816,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,58096,DB00635,10042128,172,32881,50,23744,1.85475004193635e-09,2.484027218,1.802594016,3.477028616,4.87277409818062e-08,DB0063510042128_,16.83701734,0.909881121,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,58105,DB00820,10039163,265,11650,85,5731,0.000542316,1.533633902,1.194292818,1.986075368,0.003300481,DB0082010039163_,5.713687109,0.427640018,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,tadalafil,DB00820
,58108,DB00563,10022062,58,46588,13,15335,0.270170538,1.468529281,0.79503155,2.922468311,0.432829438,DB0056310022062_,0.837411536,0.384261411,NA,10022062,Injection site extravasation,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,58109,DB00005,10063797,137,127945,38,42381,0.381591529,1.194215949,0.828232703,1.759202316,0.551712505,DB0000510063797_,0.594728192,0.17748986,NA,10063797,Cataract operation,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,58122,DB00682,10040829,98,19361,44,16320,0.000375183,1.877381064,1.301865369,2.745561327,0.002431684,DB0068210040829_,6.019171192,0.629877755,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,58125,DB00007,10003549,25,1922,169,4283,1.11274134560885e-08,0.329690756,0.206731151,0.505732289,2.48078085405672e-07,DB0000710003549_,15.20952228,-1.109600167,male,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,leuprolide,DB00007
,58127,DB01156,10003549,254,13368,131,6197,0.347180746,0.898839196,0.723467501,1.120944122,0.51659473,DB0115610003549_,0.6604966,-0.10665113,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,58131,DB00787,10008469,76,16924,50,17198,0.019949763,1.544580124,1.066205907,2.254795275,0.061637324,DB0078710008469_,2.786487686,0.434752109,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,58132,DB01156,10008469,85,13537,13,6315,4.32433788850348e-05,3.050045474,1.689999851,5.966625405,0.000390535,DB0115610008469_,7.847992879,1.1151565,female,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,58135,DB00126,10010264,201,9970,60,5885,1.46416197950224e-06,1.977328816,1.472332792,2.689267249,2.01547513124988e-05,DB0012610010264_,10.8120705,0.681746851,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,58137,DB01156,10010264,245,13377,107,6221,0.643941026,1.064834424,0.843311811,1.351966945,0.780197279,DB0115610010264_,0.24820847,0.062819316,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,58142,DB00316,10011469,153,65321,28,36925,1.2492658747728e-09,3.088843768,2.054189773,4.80319694,3.41163153437953e-08,DB0031610011469_,17.19349011,1.127796836,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,58144,DB01156,10011469,70,13552,9,6319,4.58943455850847e-05,3.626136197,1.803565484,8.263851427,0.000410511,DB0115610011469_,7.798107971,1.288167673,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,58147,DB00007,10013709,95,1852,152,4300,0.005915284,1.451051528,1.104272749,1.8989061,0.023403814,DB0000710013709_,3.754856283,0.372288485,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,leuprolide,DB00007
,58150,DB00007,10016322,15,1932,38,4414,0.88092592,0.901863516,0.459735467,1.682917429,0.950123172,DB0000710016322_,0.051163648,-0.103292083,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,leuprolide,DB00007
,58151,DB00126,10016322,223,9948,88,5857,0.00133839,1.491939843,1.158063197,1.936097654,0.006998127,DB0012610016322_,4.962112763,0.400077181,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,58153,DB00787,10016322,203,16797,158,17090,0.012800255,1.307207355,1.055360452,1.621576224,0.043354772,DB0078710016322_,3.138338511,0.267893072,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,58165,DB00007,10022437,36,1911,62,4390,0.184337306,1.333842559,0.855962062,2.051180897,0.329336882,DB0000710022437_,1.110674093,0.288063918,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,leuprolide,DB00007
,58170,DB00787,10024855,83,16917,68,17180,0.192938296,1.239553753,0.888056332,1.735331376,0.340304185,DB0078710024855_,1.077915401,0.214751438,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,58173,DB00338,10027175,413,33261,171,22101,1.23016066643708e-07,1.604820644,1.338437977,1.930940258,2.19740218262308e-06,DB0033810027175_,13.02823472,0.473012002,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,58175,DB00787,10027175,158,16842,100,17148,0.000213848,1.608674202,1.24319885,2.089875022,0.00152372,DB0078710027175_,6.486600661,0.475410363,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,58179,DB00316,10027951,87,65387,34,36919,0.07198168,1.444765293,0.96141697,2.216152635,0.164739962,DB0031610027951_,1.803387039,0.367946882,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,58185,DB00007,10033775,31,1916,30,4422,0.001080791,2.38452061,1.391846352,4.090417866,0.005873792,DB0000710033775_,5.1372548,0.868998102,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,leuprolide,DB00007
,58187,DB01156,10033775,169,13453,50,6278,0.004307116,1.577283565,1.14249222,2.211345459,0.018138674,DB0115610033775_,4.009708918,0.455704105,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,58201,DB01156,10041466,48,13574,12,6316,0.05218483,1.861154131,0.973060668,3.852106741,0.129135592,DB0115610041466_,2.046892326,0.621196796,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,58204,DB00264,10049816,32,29575,19,24873,0.261396434,1.416433552,0.778599208,2.645604004,0.422935906,DB0026410049816_,0.860534634,0.348142129,NA,10049816,Muscle tightness,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,58205,DB00338,10049816,38,33636,24,22248,0.897444703,1.047274842,0.611957866,1.825550478,0.956338178,DB0033810049816_,0.044643686,0.046191402,NA,10049816,Muscle tightness,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,58211,DB00338,10050256,64,33610,27,22245,0.053420041,1.568831675,0.985785626,2.560145097,0.131400504,DB0033810050256_,2.029505338,0.450331186,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,58218,DB00787,10052904,70,16930,44,17204,0.014372672,1.616624061,1.092532191,2.415018361,0.047598043,DB0078710052904_,3.044963624,0.480340062,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,58219,DB01156,10052904,62,13560,27,6301,0.82041022,1.067028387,0.668159379,1.746193735,0.90434181,DB0115610052904_,0.100547881,0.064877577,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,58221,DB00126,10060800,74,10097,21,5924,0.00264362,2.067364623,1.257620614,3.538466241,0.01219401,DB0012610060800_,4.406810469,0.726274667,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,ascorbic acid,DB00126
,58222,DB00264,10060800,116,29491,55,24837,0.000379371,1.776230534,1.277368442,2.496170699,0.002455195,DB0026410060800_,6.009549159,0.574493441,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,58223,DB00787,10060800,55,16945,32,17216,0.013165769,1.746198323,1.108901664,2.791998396,0.04433853,DB0078710060800_,3.115901223,0.557441038,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,acyclovir,DB00787
,58224,DB01156,10060800,81,13541,12,6316,4.40135125616793e-05,3.148243735,1.705942002,6.348535675,0.000396604,DB0115610060800_,7.832571124,1.146844753,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,bupropion,DB01156
,58226,DB00404,10005724,65,19827,15,9847,0.005896284,2.152084186,1.21320319,4.065454072,0.02334973,DB0040410005724_,3.757169844,0.766436761,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,alprazolam,DB00404
,58227,DB00476,10005724,69,17188,18,6159,0.272520496,1.373558279,0.807581968,2.454673839,0.435505418,DB0047610005724_,0.831248041,0.317404657,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,duloxetine,DB00476
,58231,DB01222,10005724,39,9235,16,5389,0.264118207,1.422348268,0.775858902,2.729095992,0.426015408,DB0122210005724_,0.853279765,0.352309216,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,budesonide,DB01222
,58232,DB13961,10005724,51,9406,17,6397,0.009126401,2.040200855,1.157594915,3.772280642,0.033090208,DB1396110005724_,3.408517869,0.713048262,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,fish oil,DB13961
,58233,DB00153,10028334,170,7253,46,3393,0.000841261,1.728771536,1.23808897,2.456083767,0.00477232,DB0015310028334_,5.344922619,0.547411062,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,58234,DB00476,10028334,311,16946,96,6081,0.211999515,1.162499176,0.920025149,1.479955289,0.363784648,DB0047610028334_,1.011193212,0.150572149,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,58235,DB00661,10028334,46,3482,11,1584,0.0607152,1.902147039,0.967345745,4.083364593,0.144725961,DB0066110028334_,1.932913246,0.642983269,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,verapamil,DB00661
,58236,DB00722,10028334,359,25044,273,25759,0.000192648,1.352548146,1.151196048,1.590554477,0.001396129,DB0072210028334_,6.574051518,0.301990329,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,58237,DB13961,10028334,198,9259,93,6321,0.003080587,1.453428788,1.127909669,1.884089011,0.013828577,DB1396110028334_,4.281018006,0.373925447,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,58238,DB00404,10028372,156,19736,59,9803,0.080859882,1.313353444,0.966396208,1.805259187,0.179814045,DB0040410028372_,1.715832047,0.272583747,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,58239,DB00476,10028372,182,17075,50,6127,0.099601254,1.306103246,0.948994841,1.826460206,0.210170636,DB0047610028372_,1.559835527,0.267048083,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,58241,DB01222,10028372,78,9196,30,5375,0.056754146,1.519641304,0.984237268,2.402389761,0.137346455,DB0122210028372_,1.985248679,0.418474323,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,budesonide,DB01222
,58243,DB00661,10033425,84,3444,17,1578,0.001503155,2.263686158,1.327663769,4.082486397,0.007707094,DB0066110033425_,4.865614076,0.816994528,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,verapamil,DB00661
,58244,DB00811,10033425,47,2751,29,4127,0.000144765,2.431026078,1.4944581,4.016355611,0.001094534,DB0081110033425_,6.817426778,0.888313423,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ribavirin,DB00811
,58245,DB01098,10033425,215,7934,142,7067,0.006182138,1.348601536,1.083229767,1.683243002,0.02423736,DB0109810033425_,3.71986004,0.299068156,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,58246,DB01222,10033425,187,9087,62,5343,6.49172957438562e-05,1.773366855,1.32108498,2.408378919,0.000550347,DB0122210033425_,7.504961426,0.572879918,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,budesonide,DB01222
,58247,DB00661,10047700,89,3439,25,1570,0.031748938,1.625100239,1.028200943,2.654809212,0.088535717,DB0066110047700_,2.424349227,0.485569499,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,verapamil,DB00661
,58248,DB13961,10047700,258,9199,105,6309,5.0311869560612e-06,1.685139243,1.334781354,2.14000574,5.95697068198507e-05,DB1396110047700_,9.728363388,0.521848197,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,58249,DB00005,10025421,89,127993,33,42386,0.600411274,0.893112341,0.592756112,1.375440562,0.744829051,DB0000510025421_,0.294600549,-0.113042905,NA,10025421,Macule,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,58251,DB00373,10015946,69,1763,34,1253,0.084716389,1.442179526,0.936578873,2.258261938,0.186286049,DB0037310015946_,1.680471889,0.366155529,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,timolol,DB00373
,58252,DB00381,10015946,72,29288,25,22862,0.000298732,2.248040736,1.408267415,3.700359437,0.002010796,DB0038110015946_,6.209224385,0.810059053,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,amlodipine,DB00381
,58253,DB00451,10015946,133,47138,17,15402,5.92689025119286e-05,2.556372269,1.537071052,4.520666234,0.000510614,DB0045110015946_,7.579896771,0.938589171,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,levothyroxine,DB00451
,58254,DB00484,10015946,152,2355,80,1700,0.028203373,1.371450053,1.031487047,1.834564658,0.080701682,DB0048410015946_,2.516995855,0.315868613,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,brimonidine,DB00484
,58255,DB00335,10047513,91,8375,30,5435,0.000993816,1.968404623,1.288112857,3.086059679,0.00547239,DB0033510047513_,5.208039745,0.677223379,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,atenolol,DB00335
,58256,DB00373,10047513,60,1772,28,1259,0.07851814,1.522294763,0.950589442,2.491509703,0.175878759,DB0037310047513_,1.737960389,0.420218909,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,timolol,DB00373
,58257,DB00484,10047513,101,2406,59,1721,0.252340723,1.224430843,0.873799229,1.728770816,0.412460413,DB0048410047513_,0.885615046,0.202476118,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,brimonidine,DB00484
,58258,DB00869,10047513,42,1263,28,901,0.806811624,1.070053123,0.642401224,1.807163022,0.895605538,DB0086910047513_,0.11025521,0.067708295,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,dorzolamide,DB00869
,58261,DB00381,10047531,53,29307,26,22861,0.05391282,1.590090654,0.976455076,2.650079422,0.132346343,DB0038110047531_,2.022332984,0.46379103,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,amlodipine,DB00381
,58262,DB00484,10047531,30,2477,33,1747,0.093494485,0.641254388,0.376200782,1.089020586,0.20089124,DB0048410047531_,1.604991614,-0.44432904,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,brimonidine,DB00484
,58277,DB01156,10008479,144,13478,40,6288,0.00314461,1.679497551,1.174238294,2.450998555,0.01405835,DB0115610008479_,4.264538755,0.518494672,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,58283,DB00480,10029151,25,67403,31,67631,0.50435097,0.809182312,0.45804262,1.416209863,0.665390872,DB0048010029151_,0.407380634,-0.211731033,NA,10029151,Nephropathy,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,58293,DB00126,10035226,78,10093,69,5876,0.012659731,0.658168286,0.469125953,0.925064321,0.042964134,DB0012610035226_,3.147389601,-0.418294627,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ascorbic acid,DB00126
,58294,DB00158,10035226,78,16737,70,8034,0.00019704,0.534863427,0.381918082,0.75033818,0.00142305,DB0015810035226_,6.554953147,-0.625743841,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,folic acid,DB00158
,58295,DB00451,10035226,256,47015,139,15280,2.43433620047989e-06,0.598571864,0.484597064,0.741913659,3.14430108253631e-05,DB0045110035226_,10.36733383,-0.513208687,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levothyroxine,DB00451
,58296,DB00996,10035226,230,38723,212,22213,8.4105520702409e-07,0.622378515,0.513758617,0.754184475,1.22988239869976e-05,DB0099610035226_,11.30600691,-0.474206826,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,gabapentin,DB00996
,58297,DB01136,10035226,83,9801,111,11004,0.247787641,0.839535838,0.62314027,1.127407961,0.407094077,DB0113610035226_,0.898710974,-0.174906113,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,carvedilol,DB01136
,58298,DB01373,10035226,172,22548,154,7227,5.15694395937713e-19,0.357985924,0.285889456,0.448633711,4.86715518751267e-17,DB0137310035226_,37.56143696,-1.027261611,male,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,calcium,DB01373
,58301,DB00863,10003549,338,10335,177,5663,0.640024217,1.04635632,0.867199273,1.265926549,0.777063504,DB0086310003549_,0.252233202,0.045313958,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,58302,DB01233,10003549,114,3307,59,1667,0.870131058,0.973973984,0.701007893,1.365173517,0.942295438,DB0123310003549_,0.059436426,-0.026370687,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,58303,DB00316,10041549,21,65453,37,36916,2.50148444687553e-05,0.320116063,0.178001973,0.561467513,0.000241645,DB0031610041549_,8.328042156,-1.139071651,male,10041549,Spinal cord compression,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,58312,DB00327,10051398,49,6089,58,4204,0.005636767,0.583337259,0.389641348,0.87017296,0.022523931,DB0032710051398_,3.79317693,-0.538989772,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,hydromorphone,DB00327
,58313,DB00813,10051398,72,10500,104,10064,0.007936184,0.663577797,0.483747036,0.906021261,0.029595318,DB0081310051398_,3.520139097,-0.410109179,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fentanyl,DB00813
,58317,DB01065,10001497,20,4311,53,2998,6.41276958132652e-08,0.262473741,0.148276218,0.447532518,1.2109170146923e-06,DB0106510001497_,13.62413262,-1.337604235,male,10001497,Agitation,10037175,Psychiatric disorders,Psych,melatonin,DB01065
,58319,DB00341,10042458,77,11328,38,5030,0.612546652,0.899760857,0.601542491,1.36631528,0.754420501,DB0034110042458_,0.281805373,-0.105626266,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,cetirizine,DB00341
,58325,DB00316,10022972,66,65408,44,36909,0.426896761,0.846442074,0.569224956,1.269498895,0.595577685,DB0031610022972_,0.518223446,-0.16671351,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,58329,DB00904,10022972,33,23036,17,14439,0.563046018,1.216691855,0.658264908,2.330051546,0.715116301,DB0090410022972_,0.335310091,0.196135581,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,ondansetron,DB00904
,58332,DB00332,10001053,43,2641,29,1627,0.714910419,0.913480719,0.554848669,1.523707788,0.831037518,DB0033210001053_,0.185080337,-0.09049301,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipratropium,DB00332
,58333,DB00343,10001053,50,8686,45,5050,0.041955545,0.646044323,0.42246756,0.99035533,0.109611519,DB0034310001053_,2.210812813,-0.436887166,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,58334,DB00678,10001053,55,15544,40,10684,0.834465729,0.945105928,0.617046996,1.458862931,0.914123306,DB0067810001053_,0.089789808,-0.056458265,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,58335,DB00682,10001053,154,19305,94,16270,0.014935956,1.380721085,1.060462782,1.805595442,0.049147754,DB0068210001053_,3.012924137,0.322605888,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,58337,DB01118,10001053,41,3022,40,4669,0.040082667,1.583481143,0.996455782,2.518250068,0.105849491,DB0111810001053_,2.245737093,0.459625679,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,58339,DB08932,10001053,227,19216,92,6505,0.154115595,0.835238781,0.65163838,1.078003053,0.289683096,DB0893210001053_,1.238967724,-0.18003763,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,58342,DB08932,10003549,999,18444,293,6304,0.025630889,1.165345073,1.018722962,1.336186174,0.074906372,DB0893210003549_,2.591516318,0.153017243,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,58343,DB00343,10007559,198,8538,98,4997,0.200780152,1.182500368,0.921131328,1.526111316,0.349886054,DB0034310007559_,1.050147738,0.167631153,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,diltiazem,DB00343
,58347,DB00343,10016807,195,8541,84,5011,0.020196043,1.361951575,1.046637841,1.784958265,0.062259192,DB0034310016807_,2.776449092,0.308918653,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,diltiazem,DB00343
,58349,DB01118,10016807,31,3032,47,4662,1,1.014163144,0.621345377,1.634291782,1,DB0111810016807_,0,0.014063784,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,amiodarone,DB01118
,58351,DB08932,10016807,1532,17911,535,6062,0.544539914,0.969172326,0.873917579,1.076040394,0.699501176,DB0893210016807_,0.357387803,-0.031312844,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,macitentan,DB08932
,58352,DB00175,10037400,37,8094,20,6086,0.283431362,1.391009929,0.785791303,2.53226879,0.447783221,DB0017510037400_,0.803446046,0.330030051,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,58353,DB00332,10037400,46,2638,19,1637,0.157172631,1.502240351,0.85946546,2.725043064,0.293696557,DB0033210037400_,1.225208165,0.406957561,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipratropium,DB00332
,58354,DB00524,10037400,57,1520,34,1310,0.108679019,1.444670902,0.922067998,2.294060584,0.224049257,DB0052410037400_,1.495889356,0.367881546,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metolazone,DB00524
,58355,DB00678,10037400,55,15544,26,10698,0.140438606,1.455871037,0.896921715,2.420320487,0.270455822,DB0067810037400_,1.307646514,0.375604372,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,58356,DB01118,10037400,38,3025,22,4687,0.000265335,2.67593423,1.539335134,4.760000541,0.001825505,DB0111810037400_,6.305898773,0.984298564,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,58358,DB00175,10038063,28,8103,38,6068,0.017667587,0.551824809,0.325808435,0.924275621,0.056062355,DB0017510038063_,2.881290724,-0.594524658,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,58362,DB00678,10038063,64,15535,40,10684,0.689653863,1.100397707,0.729300997,1.678105563,0.812888491,DB0067810038063_,0.207161336,0.095671667,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,58366,DB08932,10038063,93,19350,20,6577,0.065260384,1.580438323,0.966319194,2.708107584,0.152891767,DB0893210038063_,1.878025012,0.457702228,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,58368,DB00390,10038435,65,4080,38,3263,0.13469993,1.367943583,0.900389643,2.10420931,0.262202224,DB0039010038435_,1.338639226,0.313308578,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,digoxin,DB00390
,58369,DB00524,10038435,70,1507,55,1289,0.713875756,1.088621354,0.747477545,1.592064974,0.83029176,DB0052410038435_,0.185978122,0.084912082,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,metolazone,DB00524
,58382,DB08932,10061905,57,19386,18,6579,0.894433084,1.074664,0.622767893,1.941807302,0.955931269,DB0893210061905_,0.045069263,0.072008055,NA,10061905,Paracentesis,10022891,Investigations,Inv,macitentan,DB08932
,58385,DB00343,10066152,65,8671,20,5075,0.012587272,1.902092029,1.135832309,3.319552279,0.042773941,DB0034310066152_,3.151826221,0.642954348,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,diltiazem,DB00343
,58389,DB00695,10066152,160,27889,67,20461,8.68535653017168e-05,1.751993749,1.308547016,2.367996975,0.000707232,DB0069510066152_,7.254151331,0.560754425,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,furosemide,DB00695
,58392,DB08932,10066152,476,18967,154,6443,0.642886106,1.049941175,0.871692703,1.270302289,0.779278346,DB0893210066152_,0.249386985,0.048734139,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,58401,DB01373,10008469,101,22619,31,7350,0.839754232,1.058679679,0.701102761,1.640099124,0.917927349,DB0137310008469_,0.085637032,0.057022546,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,58406,DB01373,10028391,182,22538,33,7348,0.001389192,1.797974171,1.234414438,2.693454874,0.007215672,DB0137310028391_,4.931499957,0.586660571,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,58416,DB00046,10021097,90,5369,91,4601,0.29240692,0.847555175,0.62443016,1.15020937,0.457985692,DB0004610021097_,0.780917335,-0.165399339,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,insulin lispro,DB00046
,58417,DB00047,10021097,113,9172,127,8391,0.118630285,0.814011571,0.624980144,1.059133853,0.23915305,DB0004710021097_,1.430651557,-0.205780699,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,insulin glargine,DB00047
,58430,DB01373,10061599,60,22660,11,7370,0.096148132,1.773946756,0.923464386,3.744116316,0.204972141,DB0137310061599_,1.584881205,0.57320687,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,58435,DB00047,10074903,44,9241,30,8488,0.243579151,1.347130221,0.827171808,2.221470904,0.40196371,DB0004710074903_,0.911393468,0.297976568,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,58437,DB14513,10003988,184,6993,62,3502,0.007428721,1.486153889,1.105322832,2.021240053,0.028077349,DB1451310003988_,3.572792122,0.3961915,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,58445,DB00153,10012378,138,7285,41,3398,0.011786969,1.569901955,1.097721199,2.288174274,0.040592268,DB0015310012378_,3.204177678,0.451013168,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ergocalciferol,DB00153
,58447,DB06643,10012378,210,52211,22,7493,0.195541663,1.369897651,0.88053482,2.23466528,0.343708213,DB0664310012378_,1.067962201,0.31473603,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,denosumab,DB06643
,58450,DB14513,10013573,248,6929,121,3443,0.910457218,1.018432393,0.812936794,1.281414175,0.959615373,DB1451310013573_,0.041222728,0.018264575,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,58453,DB00999,10017533,77,21353,10,12229,2.56967820903127e-07,4.409568913,2.271909199,9.564010234,4.25206117245118e-06,DB0099910017533_,12.36810671,1.483776932,female,10017533,Fungal infection,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,58457,DB14513,10019211,398,6779,88,3476,3.97894919046385e-14,2.318915297,1.829461906,2.966154585,2.14536778402754e-12,DB1451310019211_,26.86771012,0.841099532,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,58459,DB00451,10020100,206,47065,50,15369,0.058929484,1.345356978,0.982963975,1.872257973,0.141444753,DB0045110020100_,1.955846074,0.296659389,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,58461,DB00999,10020100,58,21372,27,12212,0.429929063,1.227493133,0.764463354,2.017168706,0.598426468,DB0099910020100_,0.513451622,0.204973987,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,58462,DB01076,10020100,90,25657,66,25517,0.065012635,1.356182685,0.975729654,1.893422347,0.152467622,DB0107610020100_,1.880803019,0.304673904,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,58463,DB06643,10020100,253,52168,26,7489,0.122593686,1.396897251,0.930466153,2.181668948,0.245159392,DB0664310020100_,1.405846701,0.334253528,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,58466,DB00999,10020751,211,21219,86,12153,0.007623187,1.405200691,1.087365447,1.829375694,0.028655769,DB0099910020751_,3.552400494,0.340180133,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,hydrochlorothiazide,DB00999
,58468,DB00451,10025197,100,47171,32,15387,1,1.019368256,0.678218647,1.569827794,1,DB0045110025197_,0,0.019183078,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,levothyroxine,DB00451
,58470,DB00999,10025197,48,21382,19,12220,0.20373055,1.443796423,0.832534335,2.602216678,0.35352191,DB0099910025197_,1.039809816,0.367276049,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,hydrochlorothiazide,DB00999
,58471,DB01076,10025197,33,25714,33,25550,1,0.993621957,0.594185132,1.661509913,1,DB0107610025197_,0,-0.00639847,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,atorvastatin,DB01076
,58475,DB14513,10025482,256,6921,80,3484,0.000159504,1.610799453,1.244082094,2.104460997,0.001189044,DB1451310025482_,6.7346054,0.476730611,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,58476,DB00153,10027599,70,7353,10,3429,9.26589873169723e-05,3.264019483,1.67114997,7.113255606,0.000747443,DB0015310027599_,7.19885314,1.182959406,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,58478,DB00999,10027599,123,21307,16,12223,6.09313640659891e-11,4.409775789,2.608343271,7.962212334,2.0612366852954e-09,DB0099910027599_,19.9999597,1.483823847,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,58479,DB01076,10027599,122,25625,33,25550,3.20488152443052e-13,3.685754039,2.490343256,5.594258094,1.53723195017621e-11,DB0107610027599_,24.89845266,1.304475129,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,58481,DB14513,10027599,84,7093,12,3552,5.36316088805134e-06,3.50511247,1.901420847,7.062626791,6.28912263852016e-05,DB1451310027599_,9.674103889,1.254222608,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,58482,DB00153,10028836,69,7354,15,3424,0.006373984,2.141618266,1.21079547,4.037390507,0.024850217,DB0015310028836_,3.694888803,0.761561742,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,58484,DB01076,10028836,121,25626,60,25523,6.67109351525904e-06,2.008523474,1.461417211,2.78629898,7.61727597952145e-05,DB0107610028836_,9.482506642,0.697399862,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,58485,DB14513,10028836,53,7124,10,3554,0.002874001,2.64384957,1.329049291,5.836474936,0.013053934,DB1451310028836_,4.338665759,0.972236026,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,58486,DB00153,10033433,54,7369,12,3427,0.016818617,2.092631832,1.103910889,4.303664202,0.053938184,DB0015310033433_,2.919916636,0.738422524,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,58488,DB01076,10033433,88,25659,36,25547,3.34924662088835e-06,2.433876706,1.633280187,3.694898096,4.1653630201112e-05,DB0107610033433_,10.08612203,0.889485339,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,58520,DB00451,10045285,51,47220,7,15412,0.031263395,2.378054865,1.074193552,6.212159506,0.087495564,DB0045110045285_,2.436167186,0.86628287,NA,10045285,Ulcer,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,58528,DB01076,10047340,91,25656,59,25524,0.011065752,1.534416413,1.093236865,2.167919876,0.038578593,DB0107610047340_,3.255057755,0.428150122,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,atorvastatin,DB01076
,58532,DB00999,10047513,210,21220,72,12167,0.000111126,1.672316748,1.272523801,2.219475624,0.000873224,DB0099910047513_,7.043318473,0.514209939,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,hydrochlorothiazide,DB00999
,58533,DB06643,10047513,69,52352,13,7502,0.401550746,0.760593323,0.416602659,1.500718936,0.571317264,DB0664310047513_,0.559810594,-0.273656463,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,denosumab,DB06643
,58534,DB14513,10047513,64,7113,28,3536,0.656724014,1.136248458,0.716734447,1.84391852,0.79011286,DB1451310047513_,0.235579483,0.12773201,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,magnesium,DB14513
,58537,DB00999,10056819,63,21367,32,12207,0.669436825,1.124763707,0.723380326,1.780205399,0.799298051,DB0099910056819_,0.224021373,0.117572975,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,58538,DB01076,10056819,68,25679,49,25534,0.095492928,1.379905003,0.941355796,2.035792029,0.20399298,DB0107610056819_,1.589669699,0.322014658,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,58543,DB00999,10061218,51,21379,18,12221,0.080181661,1.6196123,0.929797774,2.94719232,0.178705927,DB0099910061218_,1.722013688,0.4821868,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,58544,DB01076,10061218,50,25697,30,25553,0.032927971,1.657301181,1.033137834,2.700571121,0.091120883,DB0107610061218_,2.395568266,0.505190484,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,58545,DB06643,10061218,55,52366,6,7509,0.69817674,1.314444419,0.566568775,3.737469344,0.818481172,DB0664310061218_,0.200304885,0.273414082,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,58547,DB00451,10061598,45,47226,13,15406,0.762662332,1.129214747,0.598452609,2.282142907,0.868531667,DB0045110061598_,0.140951232,0.121522477,NA,10061598,Immunodeficiency,10021428,Immune system disorders,Immun,levothyroxine,DB00451
,58560,DB00972,10006451,65,2439,19,1160,0.075217152,1.626873291,0.958061388,2.887181978,0.170210738,DB0097210006451_,1.770717973,0.486659946,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,azelastine,DB00972
,58563,DB00231,10013700,47,3249,25,2114,0.467245782,1.223177694,0.73518606,2.080613697,0.633788594,DB0023110013700_,0.456039827,0.20145214,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,temazepam,DB00231
,58564,DB00881,10013700,86,626,38,552,0.000598535,1.994605321,1.321578188,3.057318081,0.003589284,DB0088110013700_,5.629802545,0.690446197,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,quinapril,DB00881
,58566,DB00331,10024690,32,24914,20,20732,0.332653291,1.331417996,0.73821496,2.457101741,0.501623071,DB0033110024690_,0.689906295,0.286244537,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,metformin,DB00331
,58569,DB01076,10024690,44,25703,50,25533,0.536914076,0.874182568,0.569232369,1.338282328,0.693145378,DB0107610024690_,0.366515521,-0.134466038,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,atorvastatin,DB01076
,58572,DB01062,10054112,41,4445,16,1729,1,0.996752473,0.545643727,1.907977264,1,DB0106210054112_,0,-0.003252811,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,oxybutynin,DB01062
,58574,DB00715,10006451,48,4795,11,2276,0.025194551,2.071066861,1.058115118,4.430986342,0.073927079,DB0071510006451_,2.604676093,0.728063866,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,paroxetine,DB00715
,58575,DB00788,10006451,107,9249,30,5031,0.001120126,1.94001014,1.281552054,3.018358892,0.006046933,DB0078810006451_,5.108204,0.6626932,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,naproxen,DB00788
,58576,DB00887,10006451,40,2301,10,1805,0.000508889,3.136936703,1.536446048,7.054972858,0.003132955,DB0088710006451_,5.765778678,1.143246751,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,bumetanide,DB00887
,58585,DB00471,10011224,470,13719,150,5315,0.044958571,1.213888014,1.005085093,1.472836035,0.115482853,DB0047110011224_,2.158633215,0.193828443,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,58586,DB00524,10011224,51,1526,28,1316,0.066624989,1.570532492,0.965454802,2.602801995,0.155258464,DB0052410011224_,1.862664039,0.451414729,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metolazone,DB00524
,58587,DB00887,10011224,82,2259,35,1780,0.002378678,1.845800608,1.22172968,2.840365924,0.01120795,DB0088710011224_,4.4911319,0.612913117,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bumetanide,DB00887
,58591,DB00524,10013709,24,1553,35,1309,0.047091143,0.57809423,0.327146693,1.005701365,0.119637815,DB0052410013709_,2.123286308,-0.548018395,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,58592,DB00715,10013709,254,4589,96,2191,0.060133126,1.263249552,0.989184067,1.623882285,0.143723501,DB0071510013709_,1.939863955,0.23368741,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,58593,DB00887,10013709,60,2281,36,1779,0.252148257,1.299786753,0.841557963,2.03284796,0.412286829,DB0088710013709_,0.886035984,0.262200215,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,58595,DB06196,10013709,49,991,20,263,0.130621006,0.650436981,0.371870041,1.176437893,0.256652824,DB0619610013709_,1.360030988,-0.430110864,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,icatibant,DB06196
,58596,DB06404,10013709,149,2920,48,852,0.542399164,0.905747527,0.643850008,1.293355381,0.69762249,DB0640410013709_,0.360077167,-0.098994679,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,human c1-esterase inhibitor,DB06404
,58597,DB00715,10013968,207,4636,68,2219,0.008278901,1.456980934,1.097209589,1.954882318,0.030612777,DB0071510013968_,3.486337819,0.376366441,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,paroxetine,DB00715
,58601,DB00332,10021143,48,2636,27,1629,0.721131844,1.098626952,0.668838575,1.839067857,0.835521773,DB0033210021143_,0.179698872,0.094061175,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipratropium,DB00332
,58602,DB00471,10021143,69,14120,32,5433,0.374877797,0.829702582,0.537419325,1.305817597,0.544694089,DB0047110021143_,0.607530947,-0.186687978,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,58604,DB00887,10021143,46,2295,33,1782,0.819026144,1.082355449,0.674042055,1.755174791,0.903479192,DB0088710021143_,0.101502199,0.079139637,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bumetanide,DB00887
,58610,DB00471,10022004,118,14071,32,5433,0.08207275,1.423717643,0.954984323,2.178263062,0.181803661,DB0047110022004_,1.704827958,0.353271509,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,58618,DB00332,10028810,50,2634,14,1642,0.006307601,2.226012068,1.206878172,4.374650576,0.024648077,DB0033210028810_,3.703056406,0.800211674,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ipratropium,DB00332
,58619,DB00471,10028810,273,13916,79,5386,0.022583451,1.337427416,1.035415978,1.744128404,0.067926081,DB0047110028810_,2.68933521,0.29074793,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,montelukast,DB00471
,58621,DB00715,10028810,63,4780,17,2270,0.04016258,1.759781903,1.014253464,3.215833021,0.106007271,DB0071510028810_,2.244247588,0.565189883,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,paroxetine,DB00715
,58622,DB00788,10028810,134,9222,53,5008,0.053837194,1.372963611,0.989864953,1.9282171,0.132214316,DB0078810028810_,2.023331063,0.316971623,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,naproxen,DB00788
,58623,DB00887,10028810,38,2303,19,1796,0.138654934,1.559541665,0.87356583,2.874379184,0.267872914,DB0088710028810_,1.317242611,0.444391973,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,bumetanide,DB00887
,58624,DB00983,10028810,49,3452,25,1715,0.901621574,0.973737762,0.587560515,1.651325286,0.95705878,DB0098310028810_,0.043890468,-0.02661325,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,formoterol,DB00983
,58640,DB00471,10047895,258,13931,108,5357,0.47979086,0.918626668,0.729283232,1.163537699,0.644617806,DB0047110047895_,0.439097686,-0.084875476,NA,10047895,Weight decreased,10022891,Investigations,Inv,montelukast,DB00471
,58641,DB00715,10047895,97,4746,48,2239,0.787875712,0.953366781,0.665229707,1.382199863,0.885095921,DB0071510047895_,0.122059255,-0.047755579,NA,10047895,Weight decreased,10022891,Investigations,Inv,paroxetine,DB00715
,58642,DB00887,10047895,47,2294,44,1771,0.393140393,0.82469353,0.532211012,1.279963381,0.563072891,DB0088710047895_,0.574346191,-0.192743441,NA,10047895,Weight decreased,10022891,Investigations,Inv,bumetanide,DB00887
,58643,DB00983,10047895,35,3466,16,1724,0.881618081,1.08805015,0.584649062,2.111587706,0.950483399,DB0098310047895_,0.050784582,0.084387241,NA,10047895,Weight decreased,10022891,Investigations,Inv,formoterol,DB00983
,58651,DB00381,10000891,56,29304,85,22802,0.000114957,0.512657982,0.358992945,0.727095964,0.00089836,DB0038110000891_,7.014939799,-0.668146358,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,amlodipine,DB00381
,58657,DB01050,10000891,21,18087,36,9335,8.47632449731949e-06,0.301082153,0.16692484,0.530186908,9.39886899017266e-05,DB0105010000891_,9.272336103,-1.200372117,male,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,ibuprofen,DB01050
,58659,DB01076,10000891,125,25622,168,25415,0.011632666,0.738043626,0.580386675,0.936536829,0.040168763,DB0107610000891_,3.214665627,-0.303752342,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,58664,DB00706,10007559,7,1068,196,15729,0.108442669,0.525973363,0.208205331,1.108365625,0.223693589,DB0070610007559_,1.497478071,-0.642504709,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,tamsulosin,DB00706
,58665,DB01050,10007559,48,18060,37,9334,0.084865221,0.670473721,0.427288506,1.059720751,0.186558935,DB0105010007559_,1.679008086,-0.39977077,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,ibuprofen,DB01050
,58666,DB01069,10007559,48,6652,22,2373,0.340951647,0.778348414,0.459703918,1.357130306,0.510170725,DB0106910007559_,0.673009854,-0.250581022,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,promethazine,DB01069
,58670,DB00264,10011086,40,29567,46,24846,0.159346855,0.730730594,0.465946663,1.141630637,0.296620664,DB0026410011086_,1.215301181,-0.313710431,NA,10011086,Coronary artery occlusion,10007541,Cardiac disorders,Card,metoprolol,DB00264
,58678,DB00758,10011086,37,8263,37,10037,0.41476619,1.214674853,0.748242858,1.97188895,0.583969646,DB0075810011086_,0.537906274,0.194476431,NA,10011086,Coronary artery occlusion,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,58683,DB00196,10025482,150,4933,45,3240,1.66458835383031e-06,2.189142349,1.554365218,3.136207888,2.25908928808585e-05,DB0019610025482_,10.6979637,0.783509846,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,58684,DB00364,10025482,119,2631,33,1367,0.001170326,1.873362093,1.256792571,2.86118668,0.006272616,DB0036410025482_,5.071561834,0.627734727,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sucralfate,DB00364
,58685,DB00564,10025482,83,2521,36,1427,0.207874562,1.304966474,0.867293153,1.998274766,0.358729137,DB0056410025482_,1.025187668,0.26617735,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,carbamazepine,DB00564
,58686,DB00758,10025482,225,8075,170,9904,2.34846948679378e-06,1.623243945,1.321200232,1.997267519,3.04536361422667e-05,DB0075810025482_,10.39930516,0.484426582,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,58687,DB01069,10025482,264,6436,59,2336,0.000630429,1.624050961,1.215194278,2.200746015,0.003754577,DB0106910025482_,5.584779603,0.484923621,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,58688,DB00196,10044565,40,5043,41,3244,0.039497034,0.627635157,0.394730515,0.997192814,0.104649921,DB0019610044565_,2.257134589,-0.465796242,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,fluconazole,DB00196
,58690,DB00555,10044565,164,6883,54,3432,0.008683367,1.514271281,1.103790379,2.105538847,0.031810772,DB0055510044565_,3.447950296,0.414934321,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,58691,DB00706,10044565,11,1064,155,15770,0.871998859,1.051859663,0.51274662,1.94270913,0.943754349,DB0070610044565_,0.05788937,0.050559705,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,58692,DB00927,10044565,70,7427,45,4971,0.849158652,1.041156853,0.704532265,1.552318996,0.92491858,DB0092710044565_,0.078049567,0.040332453,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,58693,DB01050,10044565,172,17936,73,9298,0.175615981,1.221391116,0.922564479,1.630920373,0.31810806,DB0105010044565_,1.145364143,0.199990468,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,58713,DB00175,10013946,55,8076,25,6081,0.040903575,1.656476275,1.013642907,2.777553928,0.107450577,DB0017510013946_,2.230724287,0.50469262,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,58714,DB00381,10013946,219,29141,111,22776,0.000184071,1.542019534,1.220789295,1.956939106,0.00134472,DB0038110013946_,6.611569805,0.433092943,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,58724,DB08893,10053762,203,1882,72,986,0.006093089,1.476963682,1.110253906,1.982493232,0.023963868,DB0889310053762_,3.731208092,0.389988414,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,mirabegron,DB08893
,58726,DB09072,10007737,98,6373,42,2493,0.636079324,0.912770915,0.627679645,1.347519457,0.773810891,DB0907210007737_,0.256427762,-0.091270345,NA,10007737,Cataplexy,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,58727,DB00425,10016322,226,12469,86,7398,0.000382957,1.559134226,1.208910066,2.026186042,0.002473228,DB0042510016322_,6.002231243,0.444130684,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,58740,DB00046,10000087,54,5405,46,4646,1,1.009065216,0.666902089,1.532346366,1,DB0004610000087_,0,0.009024374,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,insulin lispro,DB00046
,58744,DB00575,10000087,68,5176,39,3790,0.238592628,1.276666726,0.84680197,1.948635022,0.396303419,DB0057510000087_,0.925575152,0.244252561,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,clonidine,DB00575
,58746,DB04861,10000087,38,1927,14,1373,0.033663692,1.933584723,1.019361729,3.879274248,0.092706309,DB0486110000087_,2.378318745,0.659375649,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,nebivolol,DB04861
,58747,DB05351,10000087,68,2655,20,1111,0.192891468,1.422672843,0.848647517,2.485852114,0.340255838,DB0535110000087_,1.078057478,0.352537386,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,dexlansoprazole,DB05351
,58748,DB01240,10003549,364,5387,75,1501,0.019429229,1.352231913,1.044575632,1.769542557,0.06042682,DB0124010003549_,2.806322225,0.301756496,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,58749,DB00682,10005734,165,19294,98,16266,0.006197536,1.419421199,1.097827333,1.843408776,0.024288392,DB0068210005734_,3.71775674,0.350249182,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,warfarin,DB00682
,58750,DB00820,10046571,261,11654,45,5771,4.873712278963e-13,2.871988351,2.083028145,4.040331007,2.27137459667629e-11,DB0082010046571_,24.50805083,1.055004595,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,tadalafil,DB00820
,58751,DB01240,10046571,131,5620,15,1561,0.000486147,2.425606883,1.412775275,4.470692962,0.003021248,DB0124010046571_,5.802085301,0.886081754,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,58759,DB00820,10012587,121,11794,14,5802,1.61571184996549e-09,4.251051702,2.43564037,8.016951663,4.30938467542799e-08,DB0082010012587_,16.95988562,1.447166412,female,10012587,Device leakage,10077536,Product issues,Prod,tadalafil,DB00820
,58760,DB06403,10012587,90,21381,17,6644,0.06745354,1.645038726,0.971649599,2.949979411,0.156793493,DB0640310012587_,1.852825669,0.497763925,NA,10012587,Device leakage,10077536,Product issues,Prod,ambrisentan,DB06403
,58761,DB01240,10020751,94,5657,9,1567,0.000962842,2.892895405,1.456174382,6.536791284,0.005340992,DB0124010020751_,5.232343884,1.062257871,female,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,epoprostenol,DB01240
,58762,DB06403,10020751,167,21304,32,6629,0.011772499,1.623807004,1.106054597,2.452999529,0.040561036,DB0640310020751_,3.204947371,0.484773395,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ambrisentan,DB06403
,58764,DB01240,10059108,41,5710,18,1558,0.109901037,0.62154844,0.348043227,1.152781508,0.225953806,DB0124010059108_,1.487424699,-0.475541431,NA,10059108,Medical device change,10042613,Surgical and medical procedures,Surg,epoprostenol,DB01240
,58766,DB01240,10064684,214,5537,66,1510,0.414468097,0.884241737,0.66384976,1.190814205,0.583675413,DB0124010064684_,0.53841025,-0.123024796,NA,10064684,Device dislocation,10077536,Product issues,Prod,epoprostenol,DB01240
,58772,DB01202,10010305,135,6579,132,5586,0.264163785,0.868373373,0.676179906,1.115419475,0.426062777,DB0120210010305_,0.85316858,-0.141133503,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,58773,DB06218,10010305,30,1664,39,1397,0.086753365,0.645900997,0.385291199,1.073087192,0.189638837,DB0621810010305_,1.662633872,-0.437109043,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,lacosamide,DB06218
,58774,DB00776,10013968,62,1843,28,1311,0.050651518,1.574898542,0.986505641,2.571312836,0.126184737,DB0077610013968_,2.070008278,0.454190852,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxcarbazepine,DB00776
,58777,DB00776,10016173,85,1820,42,1297,0.065554826,1.442083641,0.977772686,2.155131716,0.15341759,DB0077610016173_,1.874591732,0.366089041,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,oxcarbazepine,DB00776
,58780,DB01202,10016173,219,6495,151,5567,0.044187043,1.2430861,1.002477449,1.544701364,0.113963248,DB0120210016173_,2.171879272,0.217597078,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,levetiracetam,DB01202
,58781,DB06218,10016173,76,1618,48,1388,0.117770104,1.35812759,0.926822152,2.0068503,0.237847652,DB0621810016173_,1.436124926,0.306106979,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,lacosamide,DB06218
,58790,DB06218,10027175,33,1661,21,1415,0.336172981,1.338569441,0.747835975,2.44643391,0.505257999,DB0621810027175_,0.682686091,0.291601463,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,lacosamide,DB06218
,58793,DB01202,10047899,86,6628,54,5664,0.087816624,1.360924491,0.955366983,1.95349435,0.191540947,DB0120210047899_,1.65265367,0.308164242,NA,10047899,Weight increased,10022891,Investigations,Inv,levetiracetam,DB01202
,58801,DB09140,10002855,95,3646,21,1777,0.000606894,2.204561445,1.35790861,3.737534096,0.003633347,DB0914010002855_,5.617600928,0.790528598,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,oxygen,DB09140
,58802,DB09076,10009033,52,756,31,579,0.305216605,1.284466095,0.796317033,2.102081122,0.472043686,DB0907610009033_,0.750683742,0.250343142,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,umeclidinium,DB09076
,58806,DB00588,10065154,88,16436,36,8432,0.295365808,1.253994656,0.841112374,1.9048825,0.461283957,DB0058810065154_,0.773741466,0.226334181,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,fluticasone propionate,DB00588
,58810,DB00213,10051055,130,18765,136,13285,0.001737725,0.676755136,0.527453026,0.868033883,0.008656517,DB0021310051055_,4.749442798,-0.390445762,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,pantoprazole,DB00213
,58812,DB01076,10051055,132,25615,216,25367,4.46604753072546e-06,0.605204195,0.483272833,0.755570281,5.35660777299196e-05,DB0107610051055_,9.834594568,-0.502189365,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,atorvastatin,DB01076
,58813,DB13961,10051055,36,9421,86,6328,2.2017462191602e-11,0.281196604,0.184769404,0.420094282,7.96050885428143e-10,DB1396110051055_,20.95135801,-1.268701197,male,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,fish oil,DB13961
,58821,DB00046,10002855,57,5402,25,4667,0.005120459,1.969616834,1.208631355,3.295615585,0.020855609,DB0004610002855_,3.870132366,0.677839023,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,insulin lispro,DB00046
,58822,DB00047,10002855,87,9198,50,8468,0.007721255,1.601856717,1.117036245,2.318916281,0.028964347,DB0004710002855_,3.541689629,0.471163405,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,insulin glargine,DB00047
,58823,DB00572,10002855,43,2859,22,2104,0.206018568,1.438290326,0.838628756,2.533056168,0.356492869,DB0057210002855_,1.031441041,0.363455135,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,atropine,DB00572
,58824,DB00695,10002855,392,27657,112,20416,2.66005998629992e-21,2.583567484,2.087410045,3.219128503,3.19267930319148e-19,DB0069510002855_,42.5882563,0.94917119,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,58825,DB00046,10008479,91,5368,48,4644,0.005960577,1.640053342,1.141081123,2.383080417,0.023544661,DB0004610008479_,3.748856189,0.494728767,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,58826,DB00047,10008479,136,9149,118,8400,0.658610415,1.058202883,0.819280705,1.368354204,0.79153192,DB0004710008479_,0.233785072,0.056572076,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,58827,DB00230,10008479,192,19482,93,8558,0.43854656,0.906902362,0.703389209,1.176189434,0.606918145,DB0023010008479_,0.499361348,-0.097720484,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,58828,DB00295,10008479,166,14497,135,9467,0.065832631,0.803002744,0.634975839,1.016927907,0.153840938,DB0029510008479_,1.871836081,-0.219397148,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,58829,DB00904,10008479,385,22684,198,14258,0.022994502,1.222143102,1.025626321,1.45998555,0.068894475,DB0090410008479_,2.675179296,0.200605959,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,58830,DB01306,10008479,65,4143,66,3800,0.597210451,0.903324476,0.629461088,1.295966212,0.742470224,DB0130610008479_,0.297772511,-0.101673459,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,58831,DB00046,10042772,41,5418,33,4659,0.815706174,1.0683889,0.657875208,1.747055741,0.901212667,DB0004610042772_,0.104014015,0.066151813,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,insulin lispro,DB00046
,58832,DB00047,10042772,55,9230,63,8455,0.230867492,0.799725311,0.545984264,1.168340728,0.386962889,DB0004710042772_,0.949426485,-0.223486971,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,58833,DB00230,10042772,92,19582,44,8607,0.641567817,0.919036095,0.634365374,1.349234444,0.778200742,DB0023010042772_,0.250770765,-0.084429881,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,58834,DB00433,10042772,62,7594,70,5950,0.042384736,0.693996621,0.484100742,0.992818116,0.110444235,DB0043310042772_,2.203244547,-0.365288187,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,58836,DB00904,10042772,245,22824,131,14325,0.150440319,1.173846697,0.944570491,1.464096776,0.284545138,DB0090410042772_,1.25686338,0.160286131,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,58837,DB01306,10042772,32,4176,36,3830,0.464849009,0.815263256,0.489150231,1.353318539,0.631757386,DB0130610042772_,0.459249842,-0.204244205,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,insulin aspart,DB01306
,58838,DB14513,10042772,46,7131,34,3530,0.09439383,0.669744491,0.419824192,1.078077657,0.20235903,DB1451310042772_,1.597711783,-0.400858996,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,58861,DB00787,10003988,334,16666,250,16998,0.000235673,1.362596073,1.151455775,1.614076776,0.001651911,DB0078710003988_,6.40582257,0.309391757,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,58863,DB00169,10007739,230,38461,87,18088,0.090708177,1.243273919,0.966749482,1.611152925,0.19633271,DB0016910007739_,1.62794456,0.217748158,NA,10007739,Cataract,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,58864,DB00188,10007739,39,7847,38,8790,0.568520653,1.149640584,0.7154972,1.848663348,0.719547639,DB0018810007739_,0.329132544,0.139449357,NA,10007739,Cataract,10015919,Eye disorders,Eye,bortezomib,DB00188
,58865,DB00787,10007739,149,16851,97,17151,0.00066617,1.563399493,1.201449462,2.042337429,0.003933125,DB0078710007739_,5.53832096,0.446862613,NA,10007739,Cataract,10015919,Eye disorders,Eye,acyclovir,DB00787
,58868,DB01042,10016256,29,961,33,1295,0.518049302,1.184122935,0.68841959,2.026888924,0.677438866,DB0104210016256_,0.389435965,0.169002362,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,melphalan,DB01042
,58870,DB00338,10016750,38,33636,19,22253,0.345867276,1.323158648,0.743868888,2.430493643,0.515296661,DB0033810016750_,0.663012504,0.280021793,NA,10016750,Flank pain,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,58871,DB00451,10016750,43,47228,10,15409,0.424855806,1.402924677,0.693987063,3.131681816,0.593612484,DB0045110016750_,0.521528556,0.338559112,NA,10016750,Flank pain,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,58876,DB00787,10016807,84,16916,75,17173,0.427785569,1.137010839,0.822185152,1.574860805,0.596354496,DB0078710016807_,0.516919997,0.128402748,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,acyclovir,DB00787
,58879,DB00787,10030124,163,16837,143,17105,0.206849153,1.157997648,0.918402485,1.461417198,0.357500506,DB0078710030124_,1.028618502,0.146692348,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,58888,DB00008,10025482,40,1485,41,1635,0.821899707,1.074108699,0.673077158,1.712973807,0.905167545,DB0000810025482_,0.09963522,0.0714912,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,peginterferon alfa-2a,DB00008
,58892,DB00635,10057362,88,32965,56,23738,0.499337717,1.131540097,0.800002621,1.612225831,0.661147082,DB0063510057362_,0.413778949,0.123579623,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,58895,DB00635,10064355,96,32957,92,23702,0.054026198,0.75046123,0.557601036,1.010492884,0.132525652,DB0063510064355_,2.020979055,-0.287067289,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,58900,DB00005,10062544,152,127930,32,42387,0.016935147,1.573764141,1.069145097,2.382712465,0.054239105,DB0000510062544_,2.914353134,0.453470292,NA,10062544,Tooth fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,58903,DB01267,10064355,77,2775,120,3595,0.215760642,0.831299789,0.613375328,1.121077313,0.368334657,DB0126710064355_,0.99876336,-0.184764792,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,paliperidone,DB01267
,58905,DB00959,10033425,179,7899,56,4946,2.57124711716552e-06,2.001359053,1.471483771,2.758318256,3.30167222641406e-05,DB0095910033425_,10.31849639,0.693826476,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,methylprednisolone,DB00959
,58907,DB00108,10040047,129,10065,51,3244,0.221871011,0.815240948,0.583658424,1.153633576,0.375850193,DB0010810040047_,0.978564637,-0.204271568,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,natalizumab,DB00108
,58908,DB00959,10046571,216,7862,50,4952,7.00632585844823e-12,2.720812599,1.987758926,3.787056272,2.75484330874064e-10,DB0095910046571_,22.01249036,1.000930585,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,58909,DB00959,10058080,70,8008,22,4980,0.004850622,1.978605718,1.208713888,3.360302407,0.019978227,DB0095910058080_,3.913112232,0.682392414,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,58910,DB06626,10005750,30,658,63,1389,1,1.005208177,0.62171934,1.593805379,1,DB0662610005750_,0,0.005194662,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,axitinib,DB06626
,58911,DB01225,10018867,15,5029,52,4588,8.56627409929662e-07,0.263177009,0.137420321,0.475519588,1.25126154320651e-05,DB0122510018867_,11.28877319,-1.334928434,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,enoxaparin,DB01225
,58913,DB08895,10016173,501,27613,69,6577,7.68244842662265e-06,1.729383577,1.340246553,2.261427531,8.61673381240778e-05,DB0889510016173_,9.35921936,0.547765031,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,58914,DB08895,10052428,47,28067,8,6638,0.492715484,1.389452515,0.650086527,3.406420068,0.655556268,DB0889510052428_,0.422271139,0.328909796,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,58916,DB01591,10011906,57,1898,42,614,0.000128763,0.439191984,0.286458917,0.678030178,0.000989341,DB0159110011906_,6.918471254,-0.82281864,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,solifenacin,DB01591
,58917,DB01240,10043607,57,5694,12,1564,0.463873322,1.304656192,0.690008345,2.678498955,0.631086684,DB0124010043607_,0.460312051,0.265939552,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,epoprostenol,DB01240
,58918,DB06403,10043607,68,21403,19,6642,0.800634008,1.110651106,0.659341459,1.957935294,0.892233477,DB0640310043607_,0.114027435,0.104946425,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,ambrisentan,DB06403
,58919,DB01590,10013786,33,4705,25,2842,0.415833643,0.797366077,0.458864485,1.40170549,0.585033844,DB0159010013786_,0.53608558,-0.226441387,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,everolimus,DB01590
,58921,DB01590,10037087,99,4639,70,2797,0.335548991,0.852741358,0.619214928,1.179661127,0.504744491,DB0159010037087_,0.683702937,-0.159298992,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,everolimus,DB01590
,58923,DB08895,10008469,79,28035,10,6636,0.058976882,1.869911999,0.964504648,4.052195557,0.141545594,DB0889510008469_,1.955133393,0.62589137,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,58926,DB00207,10013573,209,8871,78,5377,0.000211816,1.62407193,1.243458705,2.139332209,0.001511493,DB0020710013573_,6.494657418,0.484936532,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,58940,DB01088,10010264,57,1372,17,420,1,1.026407148,0.580952327,1.90353508,1,DB0108810010264_,0,0.026064498,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,iloprost,DB01088
,58941,DB00177,10010264,72,4728,25,2825,0.019750672,1.720698271,1.07531445,2.838347419,0.061187627,DB0017710010264_,2.793810285,0.54273018,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,58942,DB00028,10016322,130,13328,28,5587,0.000829104,1.946193347,1.284123578,3.045796274,0.004716588,DB0002810016322_,5.356669638,0.665875335,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,58943,DB00177,10016322,103,4697,26,2824,3.03686209746143e-05,2.381574594,1.53218224,3.826085082,0.00028693,DB0017710016322_,8.156272347,0.867761863,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,58949,DB00203,10016100,48,13830,27,8911,0.636259757,1.145491418,0.699937507,1.910846884,0.773906548,DB0020310016100_,0.256304152,0.135833731,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,58952,DB00682,10016100,66,19393,97,16267,0.000488701,0.570751612,0.410700974,0.788952062,0.003035325,DB0068210016100_,5.797436897,-0.560801169,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,58954,DB00203,10018627,70,13808,45,8893,1,1.001850706,0.678548257,1.492536918,1,DB0020310018627_,0,0.001848995,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,sildenafil,DB00203
,58958,DB00390,10018884,89,4056,37,3264,0.000564261,1.935524396,1.301249359,2.930492352,0.003411525,DB0039010018884_,5.680595753,0.660378296,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,digoxin,DB00390
,58959,DB00524,10018884,59,1518,32,1312,0.041856295,1.593292186,1.012107551,2.549238448,0.109450131,DB0052410018884_,2.212286257,0.465802433,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,metolazone,DB00524
,58960,DB00688,10018884,48,6442,42,5336,0.832023773,0.946679466,0.611497378,1.470447206,0.912322753,DB0068810018884_,0.091761455,-0.054794716,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,mycophenolate mofetil,DB00688
,58966,DB00390,10048959,148,3997,67,3234,6.76214183224239e-05,1.787143548,1.32501,2.431371692,0.000569963,DB0039010048959_,7.469939469,0.580618562,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,58967,DB00437,10048959,180,6741,182,11364,1.68022806633739e-06,1.667155438,1.346164129,2.064803546,2.27712269779212e-05,DB0043710048959_,10.69001279,0.511118843,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,58968,DB00524,10048959,86,1491,46,1298,0.009372514,1.627292955,1.115291844,2.400516159,0.033798399,DB0052410048959_,3.387341833,0.486917871,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,58969,DB00688,10048959,80,6410,38,5340,0.003905054,1.753754525,1.175543067,2.657573486,0.016735035,DB0068810048959_,4.090250838,0.561758933,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,58970,DB00316,10005555,90,65384,49,36904,0.86028116,1.036690249,0.723942821,1.500109191,0.934173106,DB0031610005555_,0.06809352,0.036033185,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,58979,DB00788,10002424,17,9339,33,5028,9.59635729781432e-06,0.277377299,0.144735236,0.513102104,0.000104925,DB0078810002424_,9.162262562,-1.282376609,male,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,naproxen,DB00788
,58980,DB00788,10020751,117,9239,35,5026,0.001503745,1.818439477,1.234946541,2.738800186,0.007709368,DB0078810020751_,4.865319053,0.597978703,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,naproxen,DB00788
,58981,DB05679,10016256,232,6699,140,4769,0.13443758,1.179684419,0.94909044,1.470561896,0.261861631,DB0567910016256_,1.339939041,0.165246961,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,58983,DB00958,10003658,38,4556,41,2544,0.004382344,0.517562229,0.323031131,0.82743758,0.01838479,DB0095810003658_,3.996231597,-0.658625512,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,carboplatin,DB00958
,58984,DB01229,10003658,42,5699,51,2658,5.51797608373282e-06,0.384139086,0.248433418,0.591122534,6.44765509495075e-05,DB0122910003658_,9.649208951,-0.956750588,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,paclitaxel,DB01229
,58994,DB00080,10008531,72,568,128,785,0.123633277,0.777523608,0.562665602,1.068254424,0.246563027,DB0008010008531_,1.40013763,-0.251641272,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,daptomycin,DB00080
,58995,DB00080,10013968,17,623,47,866,0.018901415,0.502992941,0.268115455,0.902365562,0.05911401,DB0008010013968_,2.828287326,-0.687179143,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,daptomycin,DB00080
,58996,DB00080,10014962,20,620,74,839,3.33994128988414e-05,0.365955117,0.209106045,0.614088362,0.000311866,DB0008010014962_,8.072936063,-1.005244584,male,10014962,Eosinophilic pneumonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,daptomycin,DB00080
,59000,DB00374,10033775,112,17604,24,5700,0.071248424,1.510959441,0.964559803,2.458951137,0.163446048,DB0037410033775_,1.811272324,0.412744841,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,59002,DB00203,10012575,74,13804,18,8920,6.46448638073091e-05,2.656433075,1.569436737,4.729766492,0.000548657,DB0020310012575_,7.508037369,0.976984274,NA,10012575,Device breakage,10077536,Product issues,Prod,sildenafil,DB00203
,59010,DB08932,10012575,59,19384,9,6588,0.024407726,2.22809803,1.096756534,5.114076055,0.072198636,DB0893210012575_,2.628334132,0.80114832,NA,10012575,Device breakage,10077536,Product issues,Prod,macitentan,DB08932
,59012,DB00203,10012587,120,13758,29,8909,3.03159224844382e-07,2.679392661,1.772095833,4.174126522,4.93560868692138e-06,DB0020310012587_,12.21903455,0.98559015,NA,10012587,Device leakage,10077536,Product issues,Prod,sildenafil,DB00203
,59021,DB08932,10012587,124,19319,35,6562,0.361386991,1.203373005,0.820149053,1.807026451,0.531252317,DB0893210012587_,0.632518196,0.185128451,NA,10012587,Device leakage,10077536,Product issues,Prod,macitentan,DB08932
,59022,DB01017,10013968,40,1429,28,873,0.61309312,0.872792739,0.520972099,1.480469066,0.754896482,DB0101710013968_,0.281174649,-0.136057163,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,minocycline,DB01017
,59023,DB00203,10061428,439,13439,154,8784,9.1510371344362e-12,1.86318877,1.544059369,2.257977294,3.51659372922011e-10,DB0020310061428_,21.7683581,0.622289412,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,sildenafil,DB00203
,59024,DB00374,10061428,560,17156,152,5572,0.056692994,1.196559473,0.995762529,1.444841013,0.13728043,DB0037410061428_,1.985729513,0.179450333,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,treprostinil,DB00374
,59029,DB00193,10003549,533,18787,270,8432,0.112697438,0.886016356,0.762120107,1.031909961,0.23013146,DB0019310003549_,1.46910457,-0.121019868,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,59030,DB00395,10003549,58,2126,14,722,0.275144535,1.40674905,0.769283386,2.748214038,0.438459736,DB0039510003549_,0.824487295,0.341281404,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,carisoprodol,DB00395
,59032,DB00115,10005619,49,18376,17,10455,0.094786103,1.639884048,0.927456917,3.038988517,0.20292169,DB0011510005619_,1.59493514,0.494625537,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,59034,DB00381,10005619,50,29310,17,22870,0.002816386,2.2948707,1.300733161,4.246106429,0.012835491,DB0038110005619_,4.355541219,0.830676502,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,amlodipine,DB00381
,59037,DB00480,10005619,122,67306,80,67582,0.003039575,1.531240165,1.145384702,2.056723982,0.013663142,DB0048010005619_,4.293053439,0.426077973,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,59041,DB00115,10018884,246,18179,150,10322,0.494222671,0.931191955,0.755848214,1.150302012,0.656804057,DB0011510018884_,0.420369543,-0.071289842,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,59046,DB00193,10035528,145,19175,80,8622,0.148138377,0.815014969,0.615316873,1.085996374,0.281416345,DB0019310035528_,1.267920053,-0.204548799,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,tramadol,DB00193
,59048,DB00425,10035528,109,12586,78,7406,0.196333496,0.822312811,0.608313084,1.115912913,0.344581574,DB0042510035528_,1.065424426,-0.195634408,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,zolpidem,DB00425
,59050,DB00115,10038153,125,18300,59,10413,0.249260645,1.205498849,0.876822826,1.673774296,0.408678457,DB0011510038153_,0.894826601,0.186893464,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,59051,DB00193,10038153,68,19252,25,8677,0.432775081,1.225892564,0.764306014,2.025586213,0.601178152,DB0019310038153_,0.508863962,0.203669202,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,tramadol,DB00193
,59055,DB00115,10047942,379,18046,171,10301,0.012075569,1.265159878,1.051613717,1.527073808,0.0413451,DB0011510047942_,3.185801368,0.2351985,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,59056,DB00193,10047942,215,19105,70,8632,0.017200685,1.387753381,1.053642664,1.846618632,0.054892248,DB0019310047942_,2.902383144,0.327686167,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,tramadol,DB00193
,59057,DB00381,10047942,365,28995,205,22682,0.000153912,1.392816601,1.169530254,1.6623009,0.001152753,DB0038110047942_,6.76560215,0.331328029,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,amlodipine,DB00381
,59059,DB00425,10047942,132,12563,81,7403,0.775849107,0.960319376,0.721611902,1.284471271,0.877822795,DB0042510047942_,0.130310533,-0.040489367,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,zolpidem,DB00425
,59060,DB00761,10047942,271,15036,134,8491,0.229930257,1.142081929,0.923448722,1.417904774,0.385908742,DB0076110047942_,0.952154357,0.132852851,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,59064,DB00047,10028372,56,9229,55,8463,0.775131788,0.933702047,0.631160951,1.381730466,0.877413689,DB0004710028372_,0.130776688,-0.068597899,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin glargine,DB00047
,59066,DB00175,10055798,35,8096,37,6069,0.152986616,0.709136183,0.433106428,1.158903389,0.288158595,DB0017510055798_,1.244244272,-0.343707693,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,pravastatin,DB00175
,59067,DB00230,10055798,48,19626,33,8618,0.052890436,0.638718438,0.401275132,1.027895494,0.130476313,DB0023010055798_,2.036563577,-0.448291552,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,pregabalin,DB00230
,59068,DB00381,10055798,116,29244,98,22789,0.5809996,0.922404243,0.698403898,1.220347905,0.72942347,DB0038110055798_,0.315500824,-0.080771711,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,59069,DB00588,10055798,68,16456,35,8433,1,0.995631219,0.652317202,1.543980014,1,DB0058810055798_,0,-0.004378352,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,fluticasone propionate,DB00588
,59070,DB08910,10055798,22,16722,36,17452,0.114153289,0.637800455,0.357270763,1.114462239,0.232346228,DB0891010055798_,1.459526656,-0.449729811,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,pomalidomide,DB08910
,59071,DB00331,10037884,94,24852,83,20669,0.705786575,0.941933425,0.693200635,1.281791004,0.823674283,DB0033110037884_,0.193980115,-0.059820681,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,59075,DB00338,10013990,100,33574,53,22219,0.214775377,1.248645241,0.885896189,1.777472871,0.367154708,DB0033810013990_,1.001971973,0.222059156,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,59078,DB00480,10003553,232,67196,59,67603,9.87547495821634e-26,3.955685564,2.960229994,5.360297897,1.59739605708749e-23,DB0048010003553_,52.4910823,1.375153927,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,59079,DB08889,10029354,44,3121,53,3832,0.918626734,1.019317107,0.665578792,1.554162071,0.964051013,DB0888910029354_,0.036611068,0.0191329,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,carfilzomib,DB08889
,59081,DB00916,10003239,73,5250,29,2402,0.591502871,1.151669237,0.737340587,1.842377345,0.737822975,DB0091610003239_,0.304051354,0.141212401,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,metronidazole,DB00916
,59097,DB00682,10061623,88,19371,66,16298,0.517001579,1.121788668,0.805464824,1.568940116,0.676627489,DB0068210061623_,0.390634395,0.114924436,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,59098,DB06403,10061623,57,21414,14,6647,0.486961054,1.263772387,0.694726794,2.457500008,0.650857892,DB0640310061623_,0.429463952,0.234101206,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,59100,DB00186,10049438,39,16862,20,9988,0.686434151,1.155080834,0.657083242,2.091460316,0.810826723,DB0018610049438_,0.209700907,0.144170327,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,59103,DB06703,10011224,32,743,18,393,0.87962757,0.940381908,0.504696365,1.80367823,0.949457398,DB0670310011224_,0.051864617,-0.061469201,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gadobutrol,DB06703
,59106,DB00820,10008190,80,11835,51,5765,0.135851373,0.764142094,0.530384647,1.109606729,0.263882156,DB0082010008190_,1.332252654,-0.269001521,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,59107,DB08932,10008190,176,19267,62,6535,0.822288647,0.962835491,0.715928186,1.309590261,0.905482073,DB0893210008190_,0.0992878,-0.037872712,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,59108,DB01088,10016807,96,1333,33,404,0.589940796,0.881751392,0.577908315,1.374036072,0.736620294,DB0108810016807_,0.305682724,-0.125845131,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,iloprost,DB01088
,59111,DB09053,10047700,51,2234,58,3994,0.020629984,1.572006592,1.053460717,2.33930686,0.06334063,DB0905310047700_,2.759228294,0.452352887,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ibrutinib,DB09053
,59118,DB00331,10017822,31,24915,24,20728,0.892398738,1.07462083,0.610227157,1.914070424,0.955096839,DB0033110017822_,0.045942542,0.071967883,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,59121,DB00695,10017822,33,28016,28,20500,0.604789797,0.862394967,0.505164461,1.481820725,0.748036601,DB0069510017822_,0.290303371,-0.148041915,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,59123,DB06228,10017822,23,15889,36,16040,0.117423601,0.644972722,0.364716013,1.119143216,0.237305443,DB0622810017822_,1.43840718,-0.438547254,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,59128,DB00321,10022437,176,7271,64,2786,0.77049056,1.053697202,0.784417395,1.430529998,0.874236414,DB0032110022437_,0.134404443,0.052305124,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,amitriptyline,DB00321
,59130,DB00472,10022998,68,10691,27,4285,1,1.009434828,0.636624757,1.642698005,1,DB0047210022998_,0,0.009390598,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,59133,DB01224,10026749,59,8049,43,5874,1,1.001326091,0.66350993,1.522000163,1,DB0122410026749_,0,0.001325212,NA,10026749,Mania,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,59134,DB01224,10041466,39,8069,25,5892,0.703883502,1.139070997,0.671336107,1.966245264,0.82243856,DB0122410041466_,0.195481498,0.130213015,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,59153,DB00658,10012735,100,1203,61,1335,0.000325312,1.818802169,1.296486374,2.568779262,0.002155763,DB0065810012735_,6.139610348,0.598178135,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sevelamer,DB00658
,59166,DB00515,10035664,38,1832,90,2061,9.64616360215882e-05,0.475100623,0.314581233,0.705525967,0.000772545,DB0051510035664_,7.165819741,-0.744228659,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cisplatin,DB00515
,59167,DB00541,10035664,103,3031,122,4175,0.273265127,1.162887378,0.881987985,1.530860263,0.436231749,DB0054110035664_,0.829581641,0.150906031,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,vincristine,DB00541
,59168,DB00544,10035664,40,2395,64,2589,0.059290864,0.675680057,0.441580723,1.0229811,0.142149894,DB0054410035664_,1.950873189,-0.392035604,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,fluorouracil,DB00544
,59169,DB00997,10035664,113,5218,109,3405,0.004348303,0.67654473,0.513449139,0.891700555,0.018274065,DB0099710035664_,4.002272424,-0.390756714,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,doxorubicin,DB00997
,59187,DB00203,10022611,63,13815,23,8915,0.019704731,1.767552658,1.08013122,2.988789929,0.061088501,DB0020310022611_,2.795431623,0.569595911,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,59189,DB00635,10025082,158,32895,74,23720,0.002101525,1.539594389,1.16033292,2.058748901,0.010133662,DB0063510025082_,4.591892573,0.431518998,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,59195,DB00635,10007636,42,33011,50,23744,0.019480631,0.604210624,0.390979001,0.929627002,0.060568771,DB0063510007636_,2.803975852,-0.503832426,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,prednisone,DB00635
,59202,DB00338,10018484,34,33640,25,22247,0.691636447,0.899406381,0.520873674,1.572948825,0.814081634,DB0033810018484_,0.20569463,-0.10602031,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,omeprazole,DB00338
,59211,DB00370,10020772,36,4505,27,3636,0.800534778,1.076149586,0.634013277,1.846726546,0.892179633,DB0037010020772_,0.114087785,0.073389473,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,mirtazapine,DB00370
,59212,DB00338,10029883,35,33639,19,22253,0.578473731,1.218568836,0.678037956,2.255710005,0.72720752,DB0033810029883_,0.318543396,0.197677085,NA,10029883,Obesity,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,59236,DB00457,10028813,54,625,18,493,0.001340331,2.36476204,1.34468178,4.342398647,0.007006182,DB0045710028813_,4.960962324,0.8606774,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,prazosin,DB00457
,59237,DB00698,10028813,191,2957,15,414,0.035011271,1.782508127,1.040763209,3.280424655,0.095426272,DB0069810028813_,2.349401354,0.578021432,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,nitrofurantoin,DB00698
,59241,DB00698,10046571,313,2835,55,374,0.074790159,0.750824605,0.549962958,1.03969878,0.169499856,DB0069810046571_,1.774903204,-0.286583203,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,nitrofurantoin,DB00698
,59245,DB00698,10047700,94,3054,15,414,0.549050103,0.849560613,0.483968145,1.593480141,0.703491772,DB0069810047700_,0.351699098,-0.163035989,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,nitrofurantoin,DB00698
,59250,DB00698,10047895,55,3093,12,417,0.130369895,0.618029456,0.323627572,1.278836663,0.256268511,DB0069810047895_,1.361529515,-0.481219158,NA,10047895,Weight decreased,10022891,Investigations,Inv,nitrofurantoin,DB00698
,59256,DB00776,10010144,126,1779,68,1271,0.071410795,1.32371409,0.968791743,1.821350755,0.163711372,DB0077610010144_,1.809650326,0.28044149,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,oxcarbazepine,DB00776
,59257,DB00829,10010144,882,7170,363,4091,4.21374413060922e-07,1.386312393,1.217903906,1.580315736,6.62862664732087e-06,DB0082910010144_,11.92411292,0.326647267,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,59258,DB01104,10010144,679,14784,401,6885,0.000268646,0.788598568,0.693607949,0.897399434,0.001843938,DB0110410010144_,6.295851803,-0.237497874,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,59259,DB01224,10010144,1483,6625,916,5001,1.29514124424896e-05,1.222109046,1.115720424,1.339078827,0.00013628,DB0122410010144_,8.900797684,0.200578093,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,59260,DB01255,10010144,65,2068,12,1566,5.15760146278492e-07,4.100479016,2.185780678,8.370007198,7.97221725664814e-06,DB0125510010144_,11.7395479,1.4111038,female,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,lisdexamfetamine,DB01255
,59261,DB00776,10012735,59,1846,29,1310,0.12420986,1.443596538,0.90496908,2.349456305,0.247380974,DB0077610012735_,1.396825726,0.367137596,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,oxcarbazepine,DB00776
,59262,DB06684,10012735,48,699,19,316,0.684349267,1.141936301,0.646377579,2.092623311,0.809291424,DB0668410012735_,0.211596199,0.132725332,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,vilazodone,DB06684
,59264,DB01104,10022998,83,15380,75,7211,5.14813456959204e-05,0.518862322,0.374633152,0.719730655,0.000452874,DB0110410022998_,7.699896868,-0.656116706,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,59265,DB01255,10022998,34,2099,42,1536,0.025829528,0.592489281,0.363732879,0.958893108,0.075319408,DB0125510022998_,2.586017429,-0.523422497,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,lisdexamfetamine,DB01255
,59269,DB00254,10007882,53,5882,42,3346,0.13283148,0.717890516,0.468687368,1.105726149,0.259724426,DB0025410007882_,1.34813411,-0.331438206,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,doxycycline,DB00254
,59271,DB00254,10028810,88,5847,33,3355,0.036618829,1.530063593,1.012322466,2.362994199,0.098816891,DB0025410028810_,2.31448673,0.425309299,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,doxycycline,DB00254
,59274,DB00005,10048439,499,127583,35,42384,1.25778773846683e-28,4.736383319,3.359067852,6.878524996,2.562864395783e-26,DB0000510048439_,58.92608688,1.555273832,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,59276,DB08899,10033371,8,241,167,7966,0.252521535,1.583297822,0.664756653,3.243467905,0.412704629,DB0889910033371_,0.885023125,0.459509901,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,enzalutamide,DB08899
,59283,DB00005,10060945,118,127964,31,42388,0.29670413,1.260874441,0.84272105,1.938582474,0.462522652,DB0000510060945_,0.771059746,0.231805481,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,59284,DB00563,10060945,56,46590,29,15319,0.058149203,0.634938245,0.398438142,1.031702151,0.139942482,DB0056310060945_,1.966523781,-0.454227537,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,59288,DB00374,10005728,40,17676,21,5703,0.073837674,0.614568643,0.35349689,1.098074869,0.167920563,DB0037410005728_,1.78426425,-0.486834651,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,treprostinil,DB00374
,59294,DB00904,10033553,61,23008,48,14408,0.238393462,0.795832513,0.535977542,1.187612043,0.396041723,DB0090410033553_,0.926235712,-0.228366526,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,59295,DB01076,10033553,35,25712,30,25553,0.620038862,1.159447835,0.691311045,1.955590154,0.760598366,DB0107610033553_,0.273649832,0.147943888,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,59296,DB01611,10027599,95,11818,11,2350,0.088941959,1.717271122,0.915799517,3.562059659,0.193502914,DB0161110027599_,1.642462706,0.540736474,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,hydroxychloroquine,DB01611
,59297,DB00563,10029410,65,46581,29,15319,0.187749686,0.737121995,0.468801858,1.185105413,0.333772987,DB0056310029410_,1.097294196,-0.305001871,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,59323,DB00512,10027417,36,4701,39,5059,1,0.99337332,0.612459175,1.607181318,1,DB0051210027417_,0,-0.006648734,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,vancomycin,DB00512
,59327,DB00813,10027417,45,10527,85,10083,0.000197347,0.507102344,0.344834485,0.737016001,0.001424678,DB0081310027417_,6.553809145,-0.679042434,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,fentanyl,DB00813
,59328,DB00818,10027417,18,1402,57,1620,9.22020080629116e-05,0.365018247,0.201160576,0.632892934,0.000744442,DB0081810027417_,7.202876088,-1.007807935,male,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,propofol,DB00818
,59329,DB01202,10027417,31,6683,40,5678,0.094115098,0.658483605,0.397725992,1.080961668,0.201927627,DB0120210027417_,1.599845929,-0.417815655,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,levetiracetam,DB01202
,59417,DB00512,10011224,56,4681,54,5044,0.566558881,1.117443411,0.753327531,1.658788052,0.717911644,DB0051210011224_,0.331408776,0.111043407,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vancomycin,DB00512
,59419,DB00512,10043071,76,4661,86,5012,0.751995912,0.950260559,0.686760649,1.3126974,0.860111072,DB0051210043071_,0.150693744,-0.051019059,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,vancomycin,DB00512
,59424,DB01611,10003246,104,11809,25,2336,0.403865938,0.822940394,0.526336145,1.332608782,0.573553566,DB0161110003246_,0.555903944,-0.194871506,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,59425,DB01611,10010264,329,11584,57,2304,0.367020725,1.147997091,0.860994134,1.554419012,0.536659763,DB0161110010264_,0.622390974,0.138018764,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,59427,DB01611,10033371,627,11286,87,2274,0.001106756,1.452064234,1.153120295,1.84710304,0.005985202,DB0161110033371_,5.118465158,0.372986153,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,59430,DB00758,10009802,23,8277,36,10038,0.361606437,0.77482924,0.437974628,1.345022164,0.531441163,DB0075810009802_,0.632162787,-0.255112609,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,clopidogrel,DB00758
,59431,DB00009,10011906,138,1213,144,1407,0.41439933,1.111561921,0.86241059,1.43225199,0.583651467,DB0000910011906_,0.538451278,0.105766162,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,alteplase,DB00009
,59433,DB00758,10038063,62,8238,112,9962,0.011457681,0.669435311,0.482074843,0.922374053,0.039700124,DB0075810038063_,3.226400969,-0.401320741,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,59435,DB00451,10003285,228,47043,43,15376,0.000655177,1.73297909,1.245962158,2.461449544,0.003877365,DB0045110003285_,5.552599603,0.549841945,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,59451,DB00169,10061224,148,38543,44,18131,0.006578067,1.582275273,1.122678686,2.270009529,0.025488981,DB0016910061224_,3.669509051,0.458863857,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,59456,DB00489,10013709,51,1032,62,1072,0.44061724,0.854524908,0.572149965,1.271425137,0.60894887,DB0048910013709_,0.496020972,-0.157209627,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sotalol,DB00489
,59457,DB00273,10042458,121,8360,32,2161,0.919721149,0.97742673,0.655233216,1.496328934,0.964448671,DB0027310042458_,0.036198666,-0.022831947,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,59458,DB00425,10042458,120,12575,67,7417,0.761238474,1.056398071,0.775891277,1.448651077,0.867650712,DB0042510042458_,0.141966051,0.054865075,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,59476,DB00758,10046274,41,8259,110,9964,7.43222487800892e-06,0.449702231,0.305826081,0.649995425,8.36642530700062e-05,DB0075810046274_,9.388698756,-0.799169624,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,59481,DB00060,10037844,96,9412,25,2440,1,0.995495429,0.63393448,1.617707069,1,DB0006010037844_,0,-0.004514748,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,interferon beta-1a,DB00060
,59487,DB00335,10047571,53,8413,25,5440,0.202944316,1.3708007,0.835807105,2.3049601,0.352512232,DB0033510047571_,1.042669956,0.315395022,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,atenolol,DB00335
,59499,DB00051,10015967,47,25684,7,11413,0.004474462,2.98340171,1.339548515,7.826290857,0.018689214,DB0005110015967_,3.97980869,1.093064163,female,10015967,Eye swelling,10015919,Eye disorders,Eye,adalimumab,DB00051
,59504,DB01216,10016173,7,229,303,6812,0.410881335,0.687233448,0.270847409,1.45692963,0.580224885,DB0121610016173_,0.544339518,-0.375081237,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,finasteride,DB01216
,59505,DB01296,10016173,70,1379,31,952,0.048689342,1.558594238,0.998456864,2.482576261,0.122586939,DB0129610016173_,2.098934794,0.443784286,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,glucosamine,DB01296
,59508,DB08868,10012378,308,8894,95,2416,0.293707572,0.880688805,0.694306156,1.125566577,0.459461599,DB0886810012378_,0.777699911,-0.127050945,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,fingolimod,DB08868
,59509,DB08868,10046543,60,9142,15,2496,0.887837971,1.092094078,0.611197787,2.074673416,0.953538943,DB0886810046543_,0.047575012,0.088097025,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,fingolimod,DB08868
,59512,DB01062,10003549,148,4338,77,1668,0.040875753,0.739093101,0.554024076,0.992439788,0.107393588,DB0106210003549_,2.231254796,-0.302331384,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,59520,DB00424,10013573,64,1130,16,412,0.195966614,1.458151285,0.821648825,2.734473066,0.344237564,DB0042410013573_,1.066423266,0.37716939,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,hyoscyamine,DB00424
,59521,DB00424,10016173,43,1151,15,413,1,1.028612186,0.553145255,2.015542479,1,DB0042410016173_,0,0.028210502,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,hyoscyamine,DB00424
,59522,DB01062,10016173,318,4168,92,1653,0.008847519,1.370809649,1.07556442,1.760557595,0.032272694,DB0106210016173_,3.433533794,0.31540155,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,oxybutynin,DB01062
,59525,DB00213,10019641,30,18865,31,13390,0.153235531,0.686905063,0.401477867,1.17372869,0.28851373,DB0021310019641_,1.243012603,-0.375559188,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,pantoprazole,DB00213
,59527,DB00451,10019641,52,47219,23,15396,0.227844211,0.737172298,0.443070175,1.262419546,0.383202807,DB0045110019641_,0.959190907,-0.304933631,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,levothyroxine,DB00451
,59541,DB00706,10023547,6,1069,97,15828,1,0.915860129,0.327279691,2.07348745,1,DB0070610023547_,0,-0.087891624,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,tamsulosin,DB00706
,59542,DB01062,10023547,61,4425,8,1737,0.001684324,2.992480708,1.422911145,7.257893618,0.008446524,DB0106210023547_,4.774000313,1.096102712,female,10023547,Laboratory test abnormal,10022891,Investigations,Inv,oxybutynin,DB01062
,59545,DB14513,10023547,34,7143,43,3521,4.62145603954466e-05,0.389794439,0.240635025,0.626975161,0.00041304,DB1451310023547_,7.791966875,-0.942135757,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,magnesium,DB14513
,59555,DB00706,10049848,17,1058,136,15789,0.027616801,1.865440759,1.051677079,3.113043141,0.079397873,DB0070610049848_,2.533283704,0.623497357,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,59556,DB14513,10049848,68,7109,33,3531,1,1.023489692,0.664418984,1.605060737,1,DB1451310049848_,0,0.023218055,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,59558,DB01062,10061428,61,4425,33,1712,0.132364898,0.715206384,0.459002767,1.132251331,0.259101231,DB0106210061428_,1.35053644,-0.33518413,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,oxybutynin,DB01062
,59567,DB00005,10040907,38,128044,16,42403,0.431692533,0.786505318,0.428187035,1.511042101,0.600136406,DB0000510040907_,0.510598307,-0.240155795,NA,10040907,Skin papilloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,etanercept,DB00005
,59568,DB00635,10027175,299,32754,105,23689,3.22409218519946e-11,2.059471998,1.642500508,2.599222519,1.13904923505333e-09,DB0063510027175_,20.59307193,0.722449638,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,59569,DB01098,10027175,98,8051,66,7143,0.098294533,1.317359913,0.952770877,1.831313623,0.208305587,DB0109810027175_,1.568749111,0.275629668,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,59589,DB08910,10073133,59,16685,68,17420,0.594723706,0.905883619,0.62771346,1.30400516,0.740499401,DB0891010073133_,0.300430454,-0.098844437,NA,10073133,Plasma cell myeloma recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pomalidomide,DB08910
,59605,DB01224,10003988,106,8002,35,5882,2.22063732607532e-05,2.226061903,1.50373339,3.367618583,0.000218285,DB0122410003988_,8.429708271,0.800234061,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,quetiapine,DB01224
,59607,DB00334,10013968,88,2761,44,2768,0.000140067,2.004820318,1.375038974,2.96001581,0.001063755,DB0033410013968_,6.84595019,0.69555444,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,olanzapine,DB00334
,59613,DB00334,10039020,13,2836,65,2747,6.94339227926077e-10,0.193780611,0.09771737,0.355984726,1.98701215090222e-08,DB0033410039020_,17.73404867,-1.641028632,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,olanzapine,DB00334
,59616,DB00582,10002034,30,1100,23,1551,0.034136682,1.838662138,1.026430592,3.334099707,0.093685684,DB0058210002034_,2.367809888,0.609038208,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,voriconazole,DB00582
,59620,DB00620,10003549,99,4729,66,3066,0.872281828,0.972498821,0.70260405,1.353487777,0.944002299,DB0062010003549_,0.057626678,-0.027886416,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,59622,DB00987,10003549,48,2056,44,2884,0.043273112,1.53007878,0.990853833,2.36797415,0.112206151,DB0098710003549_,2.187417465,0.425319224,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,cytarabine,DB00987
,59623,DB01306,10003549,104,4104,111,3755,0.269114321,0.857278383,0.647201782,1.134772552,0.431624,DB0130610003549_,0.840200439,-0.153992579,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,59627,DB00213,10005654,47,18848,13,13408,0.001509133,2.571803254,1.368237889,5.18313887,0.007733222,DB0021310005654_,4.862229672,0.944607308,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,59630,DB00381,10005654,40,29320,24,22863,0.377705152,1.299617246,0.764309489,2.254371849,0.54770382,DB0038110005654_,0.602020613,0.262069795,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,amlodipine,DB00381
,59637,DB00761,10005654,45,15262,16,8609,0.141106097,1.586448082,0.879016132,3.008839847,0.271448141,DB0076110005654_,1.303984166,0.461497607,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,59642,DB00213,10011224,355,18540,185,13236,0.000498699,1.369932497,1.141978038,1.647669028,0.003085398,DB0021310011224_,5.781074737,0.314761466,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,59643,DB00222,10011224,63,3143,42,3086,0.061102711,1.472700594,0.977693902,2.238373555,0.145478692,DB0022210011224_,1.927725647,0.387097854,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glimepiride,DB00222
,59644,DB00620,10011224,104,4724,54,3078,0.188824336,1.254824066,0.891780738,1.78301444,0.335082884,DB0062010011224_,1.093377364,0.226995377,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,triamcinolone,DB00620
,59645,DB00741,10011224,87,4007,64,3110,0.803708375,1.055071027,0.752514564,1.485924478,0.893803439,DB0074110011224_,0.112269395,0.053608089,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrocortisone,DB00741
,59646,DB01306,10011224,71,4137,62,3804,0.793371152,1.052992981,0.736113544,1.509574614,0.887941952,DB0130610011224_,0.118848907,0.051636567,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin aspart,DB01306
,59648,DB00512,10012735,188,4549,111,4987,2.6461501876052e-07,1.856637149,1.455375746,2.37775533,4.36349169894622e-06,DB0051210012735_,12.34223797,0.618766867,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,vancomycin,DB00512
,59649,DB00582,10012735,45,1085,44,1530,0.100923552,1.441960147,0.923030238,2.254085451,0.212188094,DB0058210012735_,1.550282161,0.366003401,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,voriconazole,DB00582
,59652,DB00338,10013971,199,33475,94,22178,0.007006507,1.402569293,1.091374885,1.813174492,0.026814663,DB0033810013971_,3.61880643,0.338305764,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,59659,DB01076,10013971,140,25607,123,25460,0.323251919,1.131674001,0.881302061,1.454705717,0.4916916,DB0107610013971_,0.709903588,0.123697953,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,59663,DB00222,10019211,114,3092,60,3068,7.9111323566103e-05,1.88505694,1.361320843,2.632739927,0.000652886,DB0022210019211_,7.334108393,0.633958027,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,glimepiride,DB00222
,59664,DB00319,10019211,39,1353,14,1839,7.73504450816916e-06,3.784845947,2.000796287,7.578447564,8.6720258006921e-05,DB0031910019211_,9.352823045,1.331005185,female,10019211,Headache,10029205,Nervous system disorders,Nerv,piperacillin,DB00319
,59665,DB00582,10019211,32,1098,34,1540,0.31210236,1.319893297,0.783278632,2.219469683,0.479617092,DB0058210019211_,0.734767219,0.277550897,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,voriconazole,DB00582
,59666,DB00646,10019211,160,3293,50,1950,5.51574061497463e-05,1.894723644,1.363874228,2.671476724,0.000480229,DB0064610019211_,7.641246747,0.639072994,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,nystatin,DB00646
,59668,DB00741,10019211,259,3835,116,3058,2.517021448569e-07,1.780245166,1.416931349,2.247490528,4.17460468939353e-06,DB0074110019211_,12.38649089,0.576751089,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,hydrocortisone,DB00741
,59669,DB00761,10019211,746,14561,189,8436,9.61655923780521e-27,2.286693337,1.942201112,2.703105356,1.68514173043807e-24,DB0076110019211_,54.74019256,0.827106816,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,59670,DB00987,10019211,75,2029,93,2835,0.474303386,1.126777409,0.815400375,1.55279388,0.639993737,DB0098710019211_,0.446296889,0.119361708,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cytarabine,DB00987
,59671,DB01306,10019211,157,4051,71,3795,2.53244396942992e-07,2.071340771,1.549500826,2.791652474,4.19441019133367e-06,DB0130610019211_,12.38175783,0.728196113,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,insulin aspart,DB01306
,59692,DB00222,10035528,32,3174,42,3086,0.242074981,0.74081875,0.451359563,1.205396108,0.400276575,DB0022210035528_,0.915599533,-0.299999286,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,glimepiride,DB00222
,59693,DB00620,10035528,42,4786,24,3108,0.704690955,1.136453042,0.670949581,1.966179586,0.822904333,DB0062010035528_,0.194915327,0.127912045,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,triamcinolone,DB00620
,59694,DB00741,10035528,33,4061,37,3137,0.145714675,0.68900494,0.416537301,1.135318068,0.278068117,DB0074110035528_,1.279889171,-0.372506838,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,hydrocortisone,DB00741
,59695,DB01306,10035528,36,4172,38,3828,0.561038673,0.869269724,0.534237897,1.412027548,0.713565505,DB0130610035528_,0.337481038,-0.140101818,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,insulin aspart,DB01306
,59698,DB00213,10035598,136,18759,107,13314,0.433544214,0.902102638,0.694362783,1.174439831,0.602055668,DB0021310035598_,0.507405367,-0.103026976,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,59700,DB00646,10035598,38,3415,23,1977,0.894046496,0.956495926,0.553525143,1.686952091,0.955860142,DB0064610035598_,0.045143671,-0.04447875,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nystatin,DB00646
,59701,DB00741,10035598,20,4074,37,3137,0.001783122,0.416266553,0.228439985,0.737690255,0.008849957,DB0074110035598_,4.727342663,-0.876429472,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrocortisone,DB00741
,59702,DB01306,10035598,22,4186,31,3835,0.13044388,0.650210117,0.358029985,1.162030122,0.256381455,DB0130610035598_,1.361088884,-0.430459711,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin aspart,DB01306
,59704,DB00186,10037423,76,16825,50,9958,0.579889762,0.899628982,0.620830286,1.313631737,0.728534671,DB0018610037423_,0.316720062,-0.105772843,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,59705,DB00213,10037423,128,18767,74,13347,0.173521228,1.230167239,0.916019373,1.662291123,0.315509405,DB0021310037423_,1.153566789,0.207150127,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,59707,DB00338,10037423,145,33529,96,22176,1,0.99898595,0.76615764,1.307504585,1,DB0033810037423_,0,-0.001014564,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,59708,DB00512,10037423,34,4703,31,5067,0.534904891,1.18163976,0.70345216,1.991498717,0.691445387,DB0051210037423_,0.368971109,0.166903101,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vancomycin,DB00512
,59711,DB00646,10037423,41,3412,13,1987,0.064252368,1.836475454,0.961853079,3.744682254,0.151075543,DB0064610037423_,1.889975285,0.607848221,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nystatin,DB00646
,59714,DB00987,10037423,26,2078,39,2889,0.801388121,0.926852171,0.539911337,1.56729923,0.892535197,DB0098710037423_,0.11368933,-0.075961196,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cytarabine,DB00987
,59715,DB01076,10037423,129,25618,106,25477,0.150653676,1.210276636,0.928194824,1.580927275,0.284825712,DB0107610037423_,1.255877824,0.190848958,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,59720,DB00213,10038776,35,18860,19,13402,0.407510338,1.30899679,0.728157044,2.42350459,0.576952371,DB0021310038776_,0.549995562,0.269261034,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,59723,DB00338,10038776,76,33598,28,22244,0.00671807,1.797007051,1.150864652,2.880465016,0.025928268,DB0033810038776_,3.652421468,0.586122531,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,59724,DB00381,10038776,50,29310,23,22864,0.034085102,1.695790555,1.015374505,2.912652866,0.093584051,DB0038110038776_,2.368895304,0.528149036,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,59730,DB00695,10038776,64,27985,30,20498,0.046783939,1.562572747,0.997423773,2.498746705,0.11904316,DB0069510038776_,2.128269164,0.44633366,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,59733,DB01076,10038776,43,25704,31,25552,0.20052357,1.378880332,0.848583589,2.264400463,0.349659151,DB0107610038776_,1.050796454,0.321271816,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,59739,DB00381,10042361,26,29334,50,22837,0.000171364,0.404833627,0.241810753,0.663099817,0.001266141,DB0038110042361_,6.671781862,-0.904279093,NA,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,59743,DB01076,10042361,24,25723,67,25516,4.56472518922915e-06,0.355315636,0.213054934,0.57424168,5.46374324220802e-05,DB0107610042361_,9.814791335,-1.03474877,male,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,59765,DB00222,10047700,86,3120,51,3077,0.004265474,1.662892996,1.15813399,2.408743652,0.018000798,DB0022210047700_,4.017339174,0.508558854,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,glimepiride,DB00222
,59766,DB00319,10047700,53,1339,32,1821,0.000328701,2.251900497,1.416545579,3.630964899,0.002174927,DB0031910047700_,6.130760399,0.811774525,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,piperacillin,DB00319
,59767,DB00512,10047700,139,4598,72,5026,1.97436241989328e-07,2.110116963,1.57150052,2.853580401,3.35620789975662e-06,DB0051210047700_,12.60469882,0.746743379,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,vancomycin,DB00512
,59768,DB00582,10047700,32,1098,33,1541,0.251960746,1.360754107,0.804762829,2.298348742,0.41204431,DB0058210047700_,0.886624386,0.308039037,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,voriconazole,DB00582
,59769,DB00620,10047700,159,4669,46,3086,3.01391874188575e-07,2.284381346,1.630336484,3.255322928,4.90835527450229e-06,DB0062010047700_,12.22457165,0.826095242,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,triamcinolone,DB00620
,59770,DB00694,10047700,36,598,33,738,0.264277857,1.346006461,0.804974453,2.257339569,0.426181383,DB0069410047700_,0.852890241,0.297142031,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,daunorubicin,DB00694
,59771,DB00987,10047700,114,1990,152,2776,0.749583797,1.046254744,0.807628702,1.352280608,0.858098955,DB0098710047700_,0.153035854,0.045216877,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cytarabine,DB00987
,59772,DB01306,10047700,153,4055,91,3775,0.000871914,1.565130261,1.194835955,2.059916088,0.004920721,DB0130610047700_,5.314300181,0.447969054,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,insulin aspart,DB01306
,59773,DB01362,10047700,35,831,31,559,0.305128462,0.759638938,0.449111966,1.290139591,0.471921249,DB0136210047700_,0.750943153,-0.274912041,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,iohexol,DB01362
,59775,DB00222,10061428,71,3135,42,3086,0.010117695,1.663912957,1.116530657,2.506955903,0.035899515,DB0022210061428_,3.327031486,0.509172032,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,glimepiride,DB00222
,59777,DB00620,10061428,76,4752,45,3087,0.640729509,1.09714359,0.746806509,1.628187987,0.777632466,DB0062010061428_,0.251501275,0.092710066,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,triamcinolone,DB00620
,59779,DB00741,10061428,69,4025,64,3110,0.33181972,0.833060093,0.582183308,1.193538371,0.50061807,DB0074110061428_,0.691911803,-0.182649499,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,hydrocortisone,DB00741
,59780,DB00987,10061428,27,2077,56,2872,0.092500214,0.666741885,0.403414288,1.077593142,0.199218987,DB0098710061428_,1.613350621,-0.405352287,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,cytarabine,DB00987
,59781,DB01076,10061428,485,25262,436,25147,0.12627191,1.107314913,0.969778322,1.264670952,0.250489433,DB0107610061428_,1.384338543,0.101938088,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,59784,DB00480,10013538,230,67198,144,67518,7.7756316164638e-06,1.604812957,1.297075009,1.991014725,8.7100991706265e-05,DB0048010013538_,9.348442288,0.473007212,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,59791,DB00924,10002034,132,10030,46,4205,0.320954231,1.203015364,0.852216182,1.725003796,0.489213626,DB0092410002034_,0.714956023,0.184831208,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,cyclobenzaprine,DB00924
,59793,DB00047,10003553,51,9234,21,8497,0.001356491,2.234542761,1.31916445,3.914738579,0.007080171,DB0004710003553_,4.950457225,0.804036626,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,59794,DB00332,10003553,87,2597,17,1639,1.69541329962395e-06,3.229077666,1.896983668,5.815374483,2.29297342838258e-05,DB0033210003553_,10.68307605,1.172196544,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipratropium,DB00332
,59797,DB00641,10003553,71,14053,18,12457,2.97034976767148e-07,3.49617322,2.060273344,6.237566985,4.85092535838738e-06,DB0064110003553_,12.23634108,1.251669005,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,59798,DB00863,10003553,104,10569,18,5822,4.96782444161397e-07,3.182541342,1.915636912,5.585659187,7.70606464726015e-06,DB0086310003553_,11.77350292,1.157680042,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,59799,DB00996,10003553,179,38774,25,22400,7.69411143417745e-15,4.13630227,2.711645707,6.565490383,4.60682731315158e-13,DB0099610003553_,28.40606681,1.419802217,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,59801,DB08932,10003553,114,19329,17,6580,0.000802384,2.282895397,1.363538902,4.057688518,0.004586422,DB0893210003553_,5.384655073,0.825444548,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,59802,DB00030,10016256,88,2118,70,1751,0.870534756,1.0393067,0.745594829,1.453189246,0.942596695,DB0003010016256_,0.059116771,0.038553856,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,insulin human,DB00030
,59803,DB01029,10016256,99,1241,55,846,0.268338486,1.226964446,0.862888215,1.759454551,0.430839223,DB0102910016256_,0.842020291,0.204543189,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,irbesartan,DB01029
,59805,DB00332,10018884,35,2649,19,1637,0.778256287,1.138358667,0.631119443,2.114157429,0.879072925,DB0033210018884_,0.128887421,0.12958746,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ipratropium,DB00332
,59806,DB00590,10018884,19,757,31,1921,0.153523413,1.555059833,0.824604137,2.861072462,0.28887324,DB0059010018884_,1.241767302,0.441514023,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,doxazosin,DB00590
,59808,DB08932,10018884,466,18977,168,6429,0.488372174,0.939704308,0.78420229,1.130371757,0.651948329,DB0893210018884_,0.42778997,-0.06219002,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,macitentan,DB08932
,59809,DB00559,10061225,51,9608,9,3297,0.073633445,1.94454134,0.946756632,4.497886083,0.167566673,DB0055910061225_,1.78637396,0.665026135,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,bosentan,DB00559
,59812,DB00115,10037855,41,18384,16,10456,0.216872337,1.457417625,0.799845025,2.783612696,0.369717508,DB0011510037855_,0.995016058,0.376666119,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,59813,DB00331,10037855,40,24906,34,20718,1,0.978639614,0.603721402,1.594576621,1,DB0033110037855_,0,-0.021591821,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,59816,DB00480,10037855,92,67336,101,67561,0.564662806,0.913950824,0.681298238,1.224715755,0.716402216,DB0048010037855_,0.333513516,-0.089978512,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,59817,DB00588,10037855,37,16487,13,8455,0.295257299,1.459567448,0.75778053,2.994137676,0.461174359,DB0058810037855_,0.773979088,0.378140123,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,59818,DB00787,10037855,30,16970,37,17211,0.464167617,0.822331489,0.490373075,1.368641023,0.631313568,DB0078710037855_,0.459952602,-0.195611694,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,59819,DB00996,10037855,58,38895,35,22390,0.829931307,0.953950697,0.616320075,1.495922526,0.910731198,DB0099610037855_,0.093507487,-0.047143289,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,59843,DB01590,10011224,136,4602,103,2764,0.089817829,0.793073133,0.606627291,1.039358021,0.194919223,DB0159010011224_,1.635170049,-0.231839839,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,everolimus,DB01590
,59844,DB01590,10016256,420,4318,366,2501,9.42480445463642e-08,0.664723674,0.571415348,0.773429945,1.71380826765907e-06,DB0159010016256_,13.27679261,-0.408383852,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,59846,DB00811,10033661,30,2768,52,4104,0.5714469,0.855423172,0.525424338,1.370014519,0.721626297,DB0081110033661_,0.326247869,-0.156158995,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,ribavirin,DB00811
,59856,DB00512,10008190,21,4716,31,5067,0.26949024,0.727863266,0.396951863,1.309962633,0.432055313,DB0051210008190_,0.83920166,-0.317642069,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,vancomycin,DB00512
,59860,DB00316,10018484,38,65436,19,36934,0.782863728,1.128875133,0.634727408,2.073302826,0.881806742,DB0031610018484_,0.12578236,0.121221679,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,acetaminophen,DB00316
,59873,DB01041,10061623,58,2987,62,3056,0.853915556,0.957087884,0.654866947,1.397145804,0.928848947,DB0104110061623_,0.073809151,-0.043860059,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,thalidomide,DB01041
,59877,DB00531,10007554,49,7203,45,6471,0.917895135,0.978228265,0.638259643,1.502375869,0.963555238,DB0053110007554_,0.037125462,-0.022012236,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,cyclophosphamide,DB00531
,59878,DB00541,10007554,19,3115,40,4257,0.145044958,0.649178151,0.354389179,1.149952133,0.27713213,DB0054110007554_,1.283260883,-0.432048099,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,vincristine,DB00541
,59879,DB00997,10007554,65,5266,38,3476,0.612982284,1.129105548,0.743466438,1.736152045,0.754777689,DB0099710007554_,0.281332024,0.121425768,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,doxorubicin,DB00997
,59882,DB00115,10002198,59,18366,10,10462,8.05096253008852e-05,3.3607546,1.704111253,7.371018717,0.000662969,DB0011510002198_,7.318783057,1.212165532,female,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,cyanocobalamin,DB00115
,59893,DB01137,10002198,42,7730,22,5571,0.253844912,1.375846117,0.801833891,2.422980701,0.414377936,DB0113710002198_,0.880976833,0.3190689,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,levofloxacin,DB01137
,59897,DB09153,10002198,35,7764,20,5679,0.413992837,1.28001884,0.717897524,2.342696951,0.583267307,DB0915310002198_,0.539109696,0.246874797,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,sodium chloride,DB09153
,59900,DB00115,10008479,275,18150,125,10347,0.036268634,1.254201864,1.010055789,1.564314282,0.098073251,DB0011510008479_,2.322040622,0.226499405,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,59903,DB00455,10008479,156,9245,78,5040,0.581201097,1.090322054,0.823695369,1.453154809,0.729571902,DB0045510008479_,0.315297352,0.086473115,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,59905,DB00471,10008479,220,13969,80,5385,0.697047465,1.060111792,0.815482907,1.389773599,0.817722601,DB0047110008479_,0.201232118,0.058374367,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,59906,DB00567,10008479,56,4463,14,2067,0.038356317,1.852413426,1.014847639,3.611787241,0.102349706,DB0056710008479_,2.279359837,0.616489344,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,59907,DB00620,10008479,59,4769,26,3106,0.117602358,1.477856504,0.9147313,2.448467444,0.237581891,DB0062010008479_,1.437242913,0.39059273,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,59909,DB00874,10008479,49,3286,34,1942,0.493262703,0.851756086,0.536728085,1.365703921,0.656001425,DB0087410008479_,0.421592318,-0.160455077,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,59910,DB00924,10008479,141,10021,63,4188,0.643642062,0.935356146,0.688599438,1.282639902,0.779960887,DB0092410008479_,0.248511505,-0.066827918,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,59912,DB01137,10008479,90,7682,51,5542,0.197837092,1.273082751,0.891480698,1.835286941,0.346387874,DB0113710008479_,1.060196109,0.241441322,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,59913,DB01233,10008479,54,3367,27,1699,1,1.00920531,0.622105751,1.672707467,1,DB0123310008479_,0,0.0091632,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,59915,DB06655,10008479,31,3657,34,2085,0.009344792,0.519879889,0.30803097,0.87457446,0.033714618,DB0665510008479_,3.389823769,-0.654157476,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,liraglutide,DB06655
,59917,DB13961,10008479,149,9308,75,6339,0.033607353,1.352947994,1.016376656,1.81376588,0.092601213,DB1396110008479_,2.379453041,0.302285911,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,59918,DB00046,10019211,180,5279,93,4599,4.52460095431872e-05,1.686079708,1.301224619,2.196666672,0.000405901,DB0004610019211_,7.809400067,0.522406135,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,insulin lispro,DB00046
,59919,DB00318,10019211,102,4181,17,1822,7.1308019629229e-05,2.614355412,1.549714072,4.676507807,0.000596067,DB0031810019211_,7.42515822,0.961017571,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,codeine,DB00318
,59922,DB00737,10019211,185,2616,25,907,2.28414987761642e-06,2.565088216,1.670441923,4.094632452,2.97516746943249e-05,DB0073710019211_,10.42262514,0.94199287,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,meclizine,DB00737
,59924,DB00924,10019211,576,9586,109,4142,4.3142433394156e-17,2.283219541,1.851034147,2.837581294,3.34020283288774e-15,DB0092410019211_,33.33274486,0.825586526,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,59927,DB06655,10019211,100,3588,25,2094,6.93760524106779e-05,2.33414839,1.487933297,3.790369557,0.000582697,DB0665510019211_,7.447843629,0.847647109,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,liraglutide,DB06655
,59930,DB00047,10027599,46,9239,10,8508,5.11508342371462e-06,4.235600817,2.106741545,9.418430562,6.04672324258528e-05,DB0004710027599_,9.713408952,1.443525188,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,59931,DB00115,10027599,143,18282,26,10446,2.45822757180969e-09,3.142489692,2.057088374,4.977852475,6.31413614400499e-08,DB0011510027599_,16.57788979,1.145015381,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,59932,DB00193,10027599,172,19148,23,8679,4.06724687865448e-10,3.389257411,2.184531027,5.494747164,1.21246083151302e-08,DB0019310027599_,18.2280287,1.220610844,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,59933,DB00207,10027599,46,9034,12,5443,0.009191688,2.309468561,1.202636194,4.793320334,0.033283306,DB0020710027599_,3.402699326,0.837017438,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,59935,DB00331,10027599,121,24825,16,20736,2.62536634755515e-17,6.316634541,3.734489921,11.40864884,2.10710700596907e-15,DB0033110027599_,33.79346048,1.843186557,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,metformin,DB00331
,59936,DB00341,10027599,122,11283,33,5035,0.010942068,1.649714842,1.113297924,2.506688705,0.038251397,DB0034110027599_,3.263575189,0.50060245,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,59939,DB00455,10027599,87,9314,18,5100,5.27986163798477e-05,2.646397796,1.578012029,4.679014841,0.000462758,DB0045510027599_,7.678306038,0.973199393,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,59940,DB00471,10027599,148,14041,13,5452,7.73869773361041e-10,4.420524891,2.504092688,8.506017261,2.19667030159773e-08,DB0047110027599_,17.63373803,1.486258443,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,59942,DB00586,10027599,92,7017,17,2788,0.002577134,2.150068994,1.269647474,3.856656093,0.011948312,DB0058610027599_,4.427165296,0.765499932,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,59943,DB00620,10027599,40,4788,10,3122,0.005274339,2.607904101,1.279301447,5.857014241,0.021343392,DB0062010027599_,3.847013113,0.958546872,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,triamcinolone,DB00620
,59944,DB00635,10027599,221,32832,38,23756,4.01243014306482e-21,4.207971156,2.970768276,6.107093228,4.71886918615028e-19,DB0063510027599_,42.19754758,1.436980621,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,59947,DB00829,10027599,107,7945,14,4440,2.45863357176683e-09,4.270726676,2.433671416,8.085851739,6.31413614400499e-08,DB0082910027599_,16.57788979,1.451783994,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,59949,DB01060,10027599,64,8523,9,5072,4.03932303742554e-06,4.231451099,2.092981385,9.683249207,4.90182853364405e-05,DB0106010027599_,9.923317159,1.442544984,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,amoxicillin,DB01060
,59950,DB01075,10027599,232,19716,35,11062,8.16289788073212e-17,3.718946728,2.596321935,5.47366133,6.12159117817529e-15,DB0107510027599_,32.72695434,1.31344049,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,59956,DB09153,10027599,91,7708,18,5681,1.29279203226942e-08,3.72573712,2.227151164,6.574891604,2.83259797081719e-07,DB0915310027599_,15.07690135,1.315264717,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,59958,DB13961,10027599,66,9391,18,6396,0.000309436,2.497140821,1.463333367,4.474029598,0.002070392,DB1396110027599_,6.180017196,0.915146406,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,59960,DB00465,10028813,132,1972,29,854,0.000707468,1.970793707,1.298497411,3.081650893,0.004130103,DB0046510028813_,5.489453017,0.678436359,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ketorolac,DB00465
,59961,DB00567,10028813,241,4278,69,2012,0.000269089,1.642575389,1.244942407,2.190662516,0.001846016,DB0056710028813_,6.294725355,0.496265369,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cephalexin,DB00567
,60003,DB08904,10013709,2119,9491,664,2895,0.586114558,0.973419101,0.883078794,1.073887101,0.733340687,DB0890410013709_,0.3101449,-0.026940559,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,60004,DB01281,10039073,346,8586,42,1756,0.001093452,1.684761353,1.214959791,2.389553108,0.005927895,DB0128110039073_,5.128086158,0.521623924,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,abatacept,DB01281
,60005,DB06273,10039073,187,4908,25,1385,0.000243125,2.110495892,1.379142099,3.359440157,0.001694203,DB0627310039073_,6.380542829,0.74692294,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,tocilizumab,DB06273
,60006,DB08904,10039073,508,11102,94,3465,1.76616683541573e-06,1.686565343,1.346196885,2.13202307,2.37339955362487e-05,DB0890410039073_,10.64860213,0.522694119,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,certolizumab pegol,DB08904
,60010,DB00761,10003988,346,14961,135,8490,0.000214156,1.454396684,1.186459615,1.7911482,0.001525703,DB0076110003988_,6.485299672,0.374591165,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,60012,DB00820,10003988,358,11557,122,5694,0.000454042,1.44572955,1.170996801,1.794973692,0.002850112,DB0082010003988_,5.860397057,0.368614073,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,60033,DB00958,10051055,47,4547,21,2564,0.446632433,1.262026056,0.737735588,2.22796026,0.614378321,DB0095810051055_,0.487144382,0.232718411,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,carboplatin,DB00958
,60036,DB00316,10000496,92,65382,27,36926,0.002125016,1.924399293,1.241171137,3.075769567,0.010226297,DB0031610000496_,4.582792726,0.654613864,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,60038,DB00530,10000496,38,1770,20,1248,0.346294312,1.339536478,0.755927018,2.442184862,0.515713654,DB0053010000496_,0.662203602,0.292323642,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,erlotinib,DB00530
,60040,DB00530,10003549,83,1725,55,1213,0.79088963,1.061165946,0.739370008,1.532974589,0.886704293,DB0053010003549_,0.120243731,0.059368253,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,erlotinib,DB00530
,60041,DB00425,10003658,86,12609,104,7380,7.42825893152901e-07,0.484003831,0.35892178,0.651321374,1.10063013537339e-05,DB0042510003658_,11.4170426,-0.725662456,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,zolpidem,DB00425
,60042,DB00433,10003658,73,7583,107,5913,3.93540177005949e-05,0.532026774,0.388787728,0.724598524,0.000359673,DB0043310003658_,7.930314492,-0.631061464,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,prochlorperazine,DB00433
,60044,DB00425,10010774,251,12444,152,7332,0.794689811,0.972938985,0.790586483,1.200618846,0.888850096,DB0042510010774_,0.117826679,-0.027433907,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,60045,DB00530,10010774,43,1765,50,1218,0.013848879,0.593592735,0.382773088,0.917064272,0.046157076,DB0053010010774_,3.075705011,-0.521561827,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,erlotinib,DB00530
,60046,DB00213,10016100,47,18848,33,13388,1,1.011659511,0.634199908,1.630873887,1,DB0021310016100_,0,0.011592063,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,60050,DB00425,10019303,60,12635,28,7456,0.321850821,1.264519894,0.793989167,2.059148765,0.490156078,DB0042510019303_,0.713031411,0.23469252,NA,10019303,Heart rate increased,10022891,Investigations,Inv,zolpidem,DB00425
,60051,DB00433,10019303,40,7616,17,6003,0.03239041,1.854514713,1.026583345,3.492214344,0.089945796,DB0043310019303_,2.408548053,0.617623052,NA,10019303,Heart rate increased,10022891,Investigations,Inv,prochlorperazine,DB00433
,60055,DB00316,10020568,25,65449,42,36911,1.04363285248953e-05,0.335697349,0.196038126,0.563868908,0.000112657,DB0031610020568_,9.091166033,-1.091545271,male,10020568,Hyperaesthesia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,60060,DB00316,10021688,89,65385,35,36918,0.07528427,1.435755457,0.960757865,2.188466878,0.170311303,DB0031610021688_,1.770127325,0.361691162,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,60064,DB00722,10021688,37,25366,26,26006,0.165156581,1.458963488,0.859698698,2.509968966,0.304342453,DB0072210021688_,1.189601723,0.377726244,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,lisinopril,DB00722
,60065,DB00433,10022437,84,7572,68,5952,0.86976408,0.97099895,0.69552822,1.359754197,0.942090076,DB0043310022437_,0.059654387,-0.029429892,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,prochlorperazine,DB00433
,60074,DB00213,10031009,62,18833,30,13391,0.090117333,1.469462612,0.935191603,2.355563526,0.195399801,DB0021310031009_,1.632707556,0.384896764,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,60075,DB00264,10031009,76,29531,43,24849,0.04231142,1.487208281,1.009653263,2.215810593,0.110321959,DB0026410031009_,2.204352285,0.396900725,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,60076,DB00316,10031009,185,65289,68,36885,0.002034343,1.536988949,1.157650217,2.061278591,0.009860357,DB0031610031009_,4.619232904,0.429825275,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,60077,DB00425,10031009,43,12652,14,7470,0.054465498,1.813383792,0.972347726,3.591679962,0.133385411,DB0042510031009_,2.014512515,0.595194598,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,60078,DB00433,10031009,51,7605,26,5994,0.083635721,1.545966995,0.944794805,2.586540932,0.184488498,DB0043310031009_,1.69016816,0.435649602,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,60080,DB00264,10037087,533,29074,290,24602,1.16032204729442e-09,1.555214079,1.344066584,1.80243106,3.18029875006608e-08,DB0026410037087_,17.26370561,0.441613208,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,60081,DB00433,10037087,125,7531,77,5943,0.100342684,1.281044556,0.954703308,1.728196233,0.211338738,DB0043310037087_,1.554293037,0.247675804,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,prochlorperazine,DB00433
,60082,DB00530,10037087,63,1745,31,1237,0.110513133,1.440466039,0.916585685,2.306236432,0.226825262,DB0053010037087_,1.48357533,0.364966699,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,erlotinib,DB00530
,60090,DB00115,10005191,85,18340,31,10441,0.033247505,1.560966585,1.022822667,2.439199976,0.091811805,DB0011510005191_,2.388014397,0.445305235,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,60092,DB00213,10005191,70,18825,35,13386,0.092274367,1.422135165,0.934245568,2.200529375,0.198857203,DB0021310005191_,1.615168283,0.352159379,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,60093,DB00316,10005191,221,65253,96,36857,0.034801966,1.3002996,1.018400042,1.670577489,0.095045943,DB0031610005191_,2.353394895,0.262594699,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,60094,DB00635,10005191,134,32919,62,23732,0.003645542,1.558105379,1.144197377,2.141954226,0.015830674,DB0063510005191_,4.145805822,0.443470582,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,60095,DB00678,10005191,74,15525,38,10686,0.149169851,1.340376301,0.89394045,2.039325318,0.282834129,DB0067810005191_,1.262894671,0.292950396,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,60096,DB01136,10005191,34,9850,37,11078,0.905719295,1.033489754,0.628740478,1.694033635,0.957861963,DB0113610005191_,0.0430516,0.032941186,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,carvedilol,DB01136
,60097,DB01373,10005191,81,22639,12,7369,0.007618792,2.196940261,1.190771823,4.429639766,0.028643345,DB0137310005191_,3.552834162,0.787065602,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,60099,DB00007,10016256,77,1870,407,4045,3.55017414918591e-14,0.409283878,0.314574043,0.526844317,1.93201506234682e-12,DB0000710016256_,26.97245758,-0.893346285,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,leuprolide,DB00007
,60101,DB00115,10023232,206,18219,82,10390,0.005533904,1.432646971,1.102611845,1.87598684,0.022183723,DB0011510023232_,3.808396469,0.359523762,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,60102,DB00316,10023232,463,65011,184,36769,3.91155838454979e-05,1.423169573,1.19653925,1.698418184,0.000358117,DB0031610023232_,7.934651573,0.352886478,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,60103,DB00678,10023232,152,15447,71,10653,0.007465963,1.476408301,1.105499885,1.987802621,0.028187711,DB0067810023232_,3.568869171,0.389612315,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,60104,DB01136,10023232,74,9810,59,11056,0.054872223,1.413508345,0.989287035,2.027417184,0.13410659,DB0113610023232_,2.009120349,0.346074802,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,carvedilol,DB01136
,60107,DB00213,10030124,281,18614,167,13254,0.066705121,1.198093314,0.984444836,1.461801035,0.155403864,DB0021310030124_,1.861727975,0.180731388,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,60108,DB00678,10030124,217,15382,123,10601,0.085367345,1.215853604,0.968721481,1.531680179,0.187349142,DB0067810030124_,1.674781332,0.195446385,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,60109,DB14726,10030124,30,1987,26,2822,0.075707726,1.638517772,0.933412781,2.894088066,0.170989654,DB1472610030124_,1.766152228,0.493792036,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,dabigatran,DB14726
,60111,DB00455,10002034,143,9258,61,5057,0.120984815,1.280512561,0.940473904,1.761150501,0.242856904,DB0045510002034_,1.41528288,0.247260436,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,loratadine,DB00455
,60113,DB00575,10002034,85,5159,71,3758,0.41410744,0.872086359,0.626960968,1.216086529,0.583373393,DB0057510002034_,0.538927829,-0.136866824,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,clonidine,DB00575
,60118,DB01024,10002034,37,2174,37,2083,0.906854212,0.958137119,0.58827689,1.560482998,0.958527544,DB0102410002034_,0.042356981,-0.042764381,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,mycophenolic acid,DB01024
,60121,DB09020,10002034,44,1910,49,1555,0.140431928,0.731132682,0.472575037,1.128173888,0.270455822,DB0902010002034_,1.307646514,-0.313160328,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,bisacodyl,DB09020
,60122,DB00047,10003988,119,9166,87,8431,0.107117725,1.258116014,0.944633682,1.68120624,0.221787271,DB0004710003988_,1.506036596,0.229615375,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin glargine,DB00047
,60123,DB00343,10003988,178,8558,69,5026,0.003342345,1.514986202,1.138497301,2.035232818,0.014759097,DB0034310003988_,4.215895618,0.415406331,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diltiazem,DB00343
,60127,DB00646,10003988,90,3363,42,1958,0.272693121,1.247526333,0.851798956,1.853082646,0.435596396,DB0064610003988_,0.831039161,0.221162657,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,nystatin,DB00646
,60129,DB00741,10003988,106,3988,59,3115,0.039122688,1.40325432,1.007460069,1.970547357,0.103872713,DB0074110003988_,2.264589042,0.338794054,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocortisone,DB00741
,60131,DB00864,10003988,51,6818,35,8357,0.008825648,1.785963874,1.13760645,2.833149035,0.032210796,DB0086410003988_,3.435453589,0.579958255,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tacrolimus,DB00864
,60133,DB01015,10003988,176,9711,95,9286,5.42257281342502e-06,1.771490941,1.37020099,2.302113309,6.34887868155353e-05,DB0101510003988_,9.664647253,0.571821531,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfamethoxazole,DB01015
,60135,DB01075,10003988,396,19552,204,10893,0.389700247,1.081492889,0.909580835,1.289037992,0.559603977,DB0107510003988_,0.580525929,0.078342391,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,60136,DB01109,10003988,67,4345,54,4216,0.315829622,1.203876805,0.826415128,1.760758574,0.483465239,DB0110910003988_,0.726775861,0.18554702,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,heparin,DB01109
,60137,DB01306,10003988,80,4128,46,3820,0.011593409,1.609270078,1.102882691,2.372548792,0.040070052,DB0130610003988_,3.217126056,0.475780709,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin aspart,DB01306
,60142,DB09020,10003988,42,1912,23,1581,0.131066898,1.509786797,0.883065655,2.6422455,0.257317356,DB0902010003988_,1.357445106,0.411968447,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bisacodyl,DB09020
,60143,DB00327,10005483,27,6111,50,4212,3.3759742000169e-05,0.372228992,0.223688321,0.607166947,0.000314784,DB0032710005483_,8.063625308,-0.988246043,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,hydromorphone,DB00327
,60145,DB00343,10005483,47,8689,55,5040,0.00043137,0.49568913,0.328001688,0.746531807,0.002729883,DB0034310005483_,5.903496557,-0.701806302,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,diltiazem,DB00343
,60150,DB00683,10005483,17,1567,51,1587,6.47319945097879e-05,0.337675224,0.1819828,0.597634402,0.000549219,DB0068310005483_,7.507013281,-1.085670721,male,10005483,Blood creatinine increased,10022891,Investigations,Inv,midazolam,DB00683
,60151,DB00813,10005483,48,10524,90,10078,0.000152373,0.510750767,0.351651976,0.733755458,0.001142435,DB0081310005483_,6.774593516,-0.671873544,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,fentanyl,DB00813
,60152,DB00818,10005483,32,1388,69,1608,0.004267291,0.537380683,0.339680549,0.834235251,0.018007023,DB0081810005483_,4.016993441,-0.62104853,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,propofol,DB00818
,60154,DB01024,10005483,24,2187,34,2086,0.147317938,0.673348745,0.380616906,1.173843398,0.280191895,DB0102410005483_,1.272280571,-0.395491889,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,mycophenolic acid,DB01024
,60155,DB01098,10005483,40,8109,62,7147,0.005234426,0.568650352,0.371761473,0.861015621,0.021224355,DB0109810005483_,3.852605951,-0.56448953,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,rosuvastatin,DB01098
,60156,DB01109,10005483,42,4370,69,4201,0.007210925,0.585195708,0.388004819,0.873383968,0.02741184,DB0110910005483_,3.596780236,-0.535808944,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,heparin,DB01109
,60157,DB01275,10005483,34,3945,55,3294,0.002567176,0.516222979,0.3254954,0.808158217,0.011911427,DB0127510005483_,4.430257107,-0.661216478,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,hydralazine,DB01275
,60158,DB01306,10005483,32,4176,43,3823,0.10497907,0.681316842,0.416311395,1.104637812,0.218493376,DB0130610005483_,1.52099958,-0.383727821,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,insulin aspart,DB01306
,60163,DB11089,10005483,63,10112,83,8324,0.005705035,0.62484798,0.442434718,0.87872602,0.022737962,DB1108910005483_,3.783719426,-0.470246891,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,docusate,DB11089
,60167,DB00316,10006482,34,65440,18,36935,0.885963449,1.066112935,0.585363318,2.005290433,0.952535694,DB0031610006482_,0.048627699,0.064019263,NA,10006482,Bronchospasm,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,60204,DB00012,10010774,82,1564,41,1272,0.012232924,1.626336537,1.095963357,2.445870952,0.041801176,DB0001210010774_,3.174830798,0.486329962,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,darbepoetin alfa,DB00012
,60205,DB00047,10010774,110,9175,94,8424,0.622434284,1.07445271,0.807042349,1.432775587,0.76261147,DB0004710010774_,0.271006592,0.071811425,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,60206,DB00343,10010774,162,8574,74,5021,0.088619011,1.281988147,0.965626184,1.715366881,0.192954829,DB0034310010774_,1.645299163,0.248412113,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,60209,DB00575,10010774,107,5137,73,3756,0.70326781,1.071716215,0.785986659,1.468159999,0.82201149,DB0057510010774_,0.196000906,0.069261303,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,clonidine,DB00575
,60212,DB00658,10010774,85,1218,54,1342,0.00219065,1.7339548,1.207047033,2.509033883,0.010480082,DB0065810010774_,4.558278802,0.550404811,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sevelamer,DB00658
,60215,DB00864,10010774,49,6820,43,8349,0.115710172,1.394967143,0.905952797,2.155003899,0.234742699,DB0086410010774_,1.449265264,0.332870862,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,60218,DB01109,10010774,66,4346,45,4225,0.069857424,1.425768646,0.959000185,2.136654189,0.161020948,DB0110910010774_,1.826220808,0.354711069,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,heparin,DB01109
,60219,DB01275,10010774,64,3915,68,3281,0.186477536,0.788790828,0.54993579,1.130190036,0.332039157,DB0127510010774_,1.102502373,-0.237254103,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,hydralazine,DB01275
,60220,DB01306,10010774,58,4150,55,3811,0.924519646,0.968397879,0.656151733,1.430787879,0.967473481,DB0130610010774_,0.033067264,-0.032112244,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,insulin aspart,DB01306
,60222,DB01390,10010774,41,1368,47,1470,0.828721397,0.937381154,0.597124392,1.466482,0.909973345,DB0139010010774_,0.094339971,-0.064665299,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sodium bicarbonate,DB01390
,60226,DB00047,10018867,17,9268,40,8478,0.000785965,0.388792811,0.20650755,0.702158923,0.004507765,DB0004710018867_,5.401953917,-0.944708697,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,insulin glargine,DB00047
,60236,DB00641,10018867,38,14086,59,12416,0.007726518,0.56772683,0.367100846,0.868590644,0.028981404,DB0064110018867_,3.541100905,-0.566114909,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,simvastatin,DB00641
,60240,DB00695,10018867,52,27997,129,20399,4.36552160031097e-15,0.293712657,0.208520326,0.408495181,2.70312686134685e-13,DB0069510018867_,28.93919701,-1.225153347,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,60243,DB00864,10018867,13,6856,47,8345,0.000220453,0.336701425,0.166954148,0.633197209,0.001563571,DB0086410018867_,6.460782831,-1.08855872,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,tacrolimus,DB00864
,60245,DB00904,10018867,48,23021,47,14409,0.034260874,0.639254161,0.418263361,0.977365608,0.093919495,DB0090410018867_,2.365317304,-0.447453156,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,ondansetron,DB00904
,60246,DB01015,10018867,23,9864,41,9340,0.016743185,0.531196328,0.304032153,0.907082068,0.053725181,DB0101510018867_,2.923873465,-0.632623593,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,sulfamethoxazole,DB01015
,60248,DB01075,10018867,24,19924,31,11066,0.001842401,0.430003262,0.241390027,0.757390688,0.009092659,DB0107510018867_,4.700287921,-0.843962484,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,diphenhydramine,DB01075
,60249,DB01098,10018867,20,8129,38,7171,0.005304802,0.464309327,0.255722862,0.819117706,0.021446856,DB0109810018867_,3.842177231,-0.767204295,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,rosuvastatin,DB01098
,60250,DB01109,10018867,15,4397,38,4232,0.001298794,0.379956288,0.193888815,0.708291097,0.00682094,DB0110910018867_,4.987757988,-0.967699063,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,heparin,DB01109
,60251,DB01137,10018867,13,7759,39,5554,1.52162741014999e-06,0.238629405,0.116769546,0.457195795,2.08583971190574e-05,DB0113710018867_,10.77775395,-1.432843538,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,levofloxacin,DB01137
,60258,DB00012,10019211,56,1590,36,1277,0.337900654,1.249242387,0.801761425,1.96834069,0.506976351,DB0001210019211_,0.679290922,0.222537277,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,darbepoetin alfa,DB00012
,60259,DB00332,10019211,150,2534,41,1615,5.82595525074081e-07,2.331287874,1.630388044,3.398424764,8.87226151597464e-06,DB0033210019211_,11.63258083,0.84642085,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ipratropium,DB00332
,60260,DB00343,10019211,530,8206,114,4981,2.51551453163226e-27,2.821781878,2.293271378,3.49628501,4.62379716531146e-25,DB0034310019211_,56.03341106,1.037368557,female,10019211,Headache,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,60262,DB00598,10019211,57,1531,24,1004,0.08260112,1.55722755,0.94384486,2.642131508,0.182712315,DB0059810019211_,1.699842414,0.442907028,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,labetalol,DB00598
,60265,DB00706,10019211,53,1022,289,15636,1.28852600195375e-09,2.805593778,2.038294998,3.799830209,3.50609792560602e-08,DB0070610019211_,17.16617703,1.031615202,female,10019211,Headache,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,60266,DB00813,10019211,251,10321,90,10078,1.12666379721122e-17,2.723264657,2.128585818,3.509855268,9.35682714366415e-16,DB0081310019211_,34.60525524,1.001831402,female,10019211,Headache,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,60269,DB01024,10019211,97,2114,39,2081,1.25076634015768e-06,2.447986541,1.662772554,3.665355479,1.74642195224673e-05,DB0102410019211_,10.95535637,0.895265867,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,mycophenolic acid,DB01024
,60270,DB01098,10019211,411,7738,174,7035,7.0199120169243e-18,2.147364522,1.788677699,2.586627965,5.97146884675907e-16,DB0109810019211_,35.05436855,0.764241286,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,60271,DB01275,10019211,125,3854,60,3289,0.000234511,1.777775161,1.291691259,2.469724039,0.001644674,DB0127510019211_,6.410213046,0.575362673,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,hydralazine,DB01275
,60273,DB01390,10019211,43,1366,29,1488,0.055553276,1.614908939,0.979111354,2.698693619,0.135267982,DB0139010019211_,2.000497419,0.479278571,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sodium bicarbonate,DB01390
,60277,DB00281,10020635,22,11436,33,5638,6.89093286329884e-05,0.328692947,0.182383122,0.581566812,0.000579147,DB0028110020635_,7.453954524,-1.112631255,male,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,lidocaine,DB00281
,60278,DB00316,10020635,93,65381,109,36844,2.22870871977489e-07,0.480801839,0.360510431,0.640162471,3.73607198337263e-06,DB0031610020635_,12.49747577,-0.73230007,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,60290,DB00695,10020635,62,27987,57,20471,0.227457188,0.795618502,0.545969583,1.161235269,0.382674317,DB0069510020635_,0.960570999,-0.228635477,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,60294,DB00813,10020635,19,10553,37,10131,0.010963599,0.49299836,0.267627998,0.88018744,0.038314032,DB0081310020635_,3.261939087,-0.707249431,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,fentanyl,DB00813
,60297,DB00904,10020635,76,22993,68,14388,0.039100767,0.699400204,0.497224697,0.985455029,0.103840733,DB0090410020635_,2.264896966,-0.357532163,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,60298,DB01015,10020635,30,9857,45,9336,0.063343427,0.631449042,0.383729332,1.025583655,0.149560473,DB0101510020635_,1.900054464,-0.459738034,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,sulfamethoxazole,DB01015
,60300,DB01075,10020635,36,19912,40,11057,0.002637401,0.499763077,0.309366848,0.804794413,0.012171728,DB0107510020635_,4.408639399,-0.693621138,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,diphenhydramine,DB01075
,60309,DB00047,10020646,27,9258,66,8452,8.77766773412872e-06,0.373495078,0.229180235,0.593332481,9.68957921299446e-05,DB0004710020646_,9.241874465,-0.984850452,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,insulin glargine,DB00047
,60312,DB00343,10020646,33,8703,45,5050,0.000216369,0.425547607,0.262677827,0.682890823,0.001539352,DB0034310020646_,6.476394014,-0.854378452,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,diltiazem,DB00343
,60319,DB00695,10020646,144,27905,180,20348,1.45020988226701e-06,0.583370252,0.464909625,0.730915115,1.9994107923099e-05,DB0069510020646_,10.82007293,-0.538933214,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,60323,DB00813,10020646,13,10559,41,10127,9.44526469537007e-05,0.304097877,0.149423096,0.579356296,0.000758884,DB0081310020646_,7.183662101,-1.190405667,male,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,fentanyl,DB00813
,60325,DB00864,10020646,48,6821,104,8288,0.000754329,0.560823719,0.389190105,0.798176132,0.004353398,DB0086410020646_,5.436798689,-0.578348649,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,tacrolimus,DB00864
,60327,DB00904,10020646,67,23002,70,14386,0.003541973,0.598650947,0.42148518,0.849674156,0.015465241,DB0090410020646_,4.169160273,-0.513076577,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,60332,DB01306,10020646,19,4189,35,3831,0.013663359,0.496509712,0.267823796,0.893813864,0.045660339,DB0130610020646_,3.086525224,-0.700152235,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,insulin aspart,DB01306
,60338,DB00047,10020772,120,9165,100,8418,0.497462455,1.102165108,0.836752819,1.454450639,0.659595353,DB0004710020772_,0.416128734,0.097276525,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,insulin glargine,DB00047
,60339,DB00343,10020772,132,8604,62,5033,0.177132851,1.245342925,0.912228562,1.716008379,0.320189568,DB0034310020772_,1.13884206,0.219410934,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,diltiazem,DB00343
,60344,DB00683,10020772,35,1549,24,1614,0.147698723,1.519322832,0.873848467,2.682961382,0.280794223,DB0068310020772_,1.270133179,0.41826473,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,midazolam,DB00683
,60345,DB00706,10020772,13,1062,184,15741,0.882402001,1.047222481,0.545298041,1.843675589,0.950859822,DB0070610020772_,0.050388628,0.046141403,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,tamsulosin,DB00706
,60346,DB00736,10020772,136,10455,64,5489,0.500847593,1.115636742,0.821384894,1.528960635,0.662328829,DB0073610020772_,0.411993125,0.109425311,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,esomeprazole,DB00736
,60347,DB00818,10020772,26,1394,37,1640,0.523658355,0.826760021,0.478089143,1.410555977,0.681792103,DB0081810020772_,0.383030502,-0.190240807,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,propofol,DB00818
,60350,DB01109,10020772,72,4340,55,4215,0.210546375,1.27134888,0.880198367,1.845153923,0.361831414,DB0110910020772_,1.016576884,0.240078447,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,heparin,DB01109
,60351,DB01306,10020772,59,4149,59,3807,0.644073238,0.917587488,0.626844463,1.343128513,0.780303514,DB0130610020772_,0.248072314,-0.086007349,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,insulin aspart,DB01306
,60355,DB09020,10020772,31,1923,24,1580,0.891789136,1.061273637,0.600093411,1.898019923,0.955008248,DB0902010020772_,0.046035302,0.059469731,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,bisacodyl,DB09020
,60434,DB00012,10037087,38,1608,23,1290,0.30106558,1.325312662,0.765105414,2.342874517,0.467338315,DB0001210037087_,0.760701841,0.281648403,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,darbepoetin alfa,DB00012
,60435,DB00332,10037087,60,2624,15,1641,0.001061112,2.501059939,1.396988128,4.759075538,0.005786959,DB0033210037087_,5.152148309,0.916714618,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ipratropium,DB00332
,60436,DB00575,10037087,103,5141,50,3779,0.016584233,1.514177768,1.066940714,2.173360204,0.053310084,DB0057510037087_,2.931629768,0.414872564,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,clonidine,DB00575
,60439,DB00658,10037087,41,1262,21,1375,0.004591481,2.126632858,1.220232432,3.810231114,0.019079452,DB0065810037087_,3.959143359,0.754539911,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,sevelamer,DB00658
,60440,DB00741,10037087,114,3980,62,3112,0.025433242,1.437632504,1.042117707,1.999051586,0.074452919,DB0074110037087_,2.597588319,0.362997666,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocortisone,DB00741
,60443,DB01306,10037087,78,4130,46,3820,0.018188469,1.56828346,1.072623093,2.315802568,0.057330644,DB0130610037087_,2.858919991,0.449981684,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,insulin aspart,DB01306
,60450,DB00381,10046555,30,29330,58,22829,3.4815637072616e-05,0.402599896,0.250005395,0.63630813,0.000323367,DB0038110046555_,8.036722208,-0.909812025,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,60457,DB00641,10046555,18,14106,35,12440,0.005654088,0.453556114,0.241700067,0.823312653,0.0225777,DB0064110046555_,3.790792576,-0.790636281,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,simvastatin,DB00641
,60461,DB00706,10046555,11,1064,143,15782,0.617770227,1.140967322,0.555268163,2.112169882,0.758753816,DB0070610046555_,0.276077907,0.131876431,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,tamsulosin,DB00706
,60462,DB00722,10046555,34,25369,61,25971,0.009878141,0.570612733,0.363509067,0.882302025,0.035215914,DB0072210046555_,3.346257198,-0.561044525,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,60469,DB00904,10046555,27,23042,48,14408,1.23774694571786e-05,0.351736645,0.21092117,0.57543883,0.000130764,DB0090410046555_,8.942113458,-1.04487255,male,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,ondansetron,DB00904
,60481,DB11089,10046555,27,10148,52,8355,0.000254939,0.427507389,0.257911463,0.693924638,0.001765066,DB1108910046555_,6.339566947,-0.849783706,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,docusate,DB11089
,60483,DB00047,10046735,94,9191,51,8467,0.002541302,1.697891902,1.193326003,2.439884557,0.011809092,DB0004710046735_,4.438885526,0.529387424,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,insulin glargine,DB00047
,60484,DB00327,10046735,65,6073,37,4225,0.363271091,1.22214857,0.802382225,1.886348911,0.532800302,DB0032710046735_,0.629608593,0.200610433,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,hydromorphone,DB00327
,60486,DB00343,10046735,54,8682,31,5064,1,1.016027976,0.640586808,1.637401028,1,DB0034310046735_,0,0.015900884,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,diltiazem,DB00343
,60487,DB00381,10046735,205,29155,107,22780,0.000711078,1.496948189,1.178416504,1.910527684,0.004147037,DB0038110046735_,5.48536125,0.403428495,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,60489,DB00455,10046735,128,9273,54,5064,0.118735387,1.294461131,0.932900758,1.817323252,0.23932822,DB0045510046735_,1.429919364,0.258094493,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,loratadine,DB00455
,60491,DB00575,10046735,39,5205,18,3811,0.108246135,1.586311031,0.884505819,2.950925872,0.223419683,DB0057510046735_,1.498703288,0.461411214,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,clonidine,DB00575
,60497,DB00695,10046735,188,27861,78,20450,1.5801044802387e-05,1.769103032,1.350796179,2.335744133,0.00016208,DB0069510046735_,8.727419404,0.570472657,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,60498,DB00706,10046735,10,1065,87,15838,0.136436836,1.709277606,0.789485682,3.308520365,0.264696626,DB0070610046735_,1.329170917,0.536070829,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,tamsulosin,DB00706
,60499,DB00741,10046735,75,4019,39,3135,0.045331753,1.500002673,1.002508333,2.275832291,0.116225626,DB0074110046735_,2.152221925,0.40546689,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocortisone,DB00741
,60500,DB00813,10046735,55,10517,29,10139,0.008437561,1.828325109,1.144728127,2.976231493,0.031077041,DB0081310046735_,3.471285968,0.603400307,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,fentanyl,DB00813
,60505,DB01109,10046735,38,4374,22,4248,0.052957817,1.677409099,0.965282852,2.982981899,0.130569009,DB0110910046735_,2.035853386,0.5172504,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,heparin,DB01109
,60506,DB01306,10046735,36,4172,18,3848,0.039516694,1.844536511,1.018408532,3.456530892,0.104691457,DB0130610046735_,2.256737761,0.612228032,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,insulin aspart,DB01306
,60512,DB11089,10046735,68,10107,28,8379,0.001380724,2.013252132,1.277573694,3.250951482,0.007182331,DB1108910046735_,4.936131332,0.699751391,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,docusate,DB11089
,60513,DB00012,10047700,99,1547,44,1269,0.000737325,1.845300289,1.270383353,2.717132742,0.004271202,DB0001210047700_,5.455859944,0.612642022,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,darbepoetin alfa,DB00012
,60514,DB00332,10047700,93,2591,31,1625,0.001916546,1.881258388,1.234223673,2.937749175,0.009399463,DB0033210047700_,4.667102737,0.631940908,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ipratropium,DB00332
,60515,DB00598,10047700,40,1548,20,1008,0.353463429,1.302197576,0.738520482,2.365716712,0.523247704,DB0059810047700_,0.647700306,0.26405328,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,labetalol,DB00598
,60518,DB01024,10047700,89,2122,44,2076,0.000198589,1.978567123,1.356296704,2.923075491,0.001432076,DB0102410047700_,6.548629987,0.682372907,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,mycophenolic acid,DB01024
,60519,DB01275,10047700,123,3856,68,3281,0.00504825,1.539002305,1.130895739,2.109228741,0.020618949,DB0127510047700_,3.881544783,0.431134353,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,hydralazine,DB01275
,60520,DB09020,10047700,87,1867,44,1560,0.007195786,1.651910291,1.129030058,2.446786011,0.027370732,DB0902010047700_,3.598281021,0.50193237,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,bisacodyl,DB09020
,60576,DB01015,10055181,30,9857,31,9350,0.797991806,0.917982309,0.536349857,1.569038972,0.890838937,DB0101510055181_,0.115591635,-0.08557716,NA,10055181,BK virus infection,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,60577,DB01024,10055181,27,2184,38,2082,0.134206552,0.677407284,0.396173883,1.143636137,0.26159579,DB0102410055181_,1.340954754,-0.389482586,NA,10055181,BK virus infection,10021881,Infections and infestations,Infec,mycophenolic acid,DB01024
,60584,DB00319,10013709,88,1304,148,1705,0.075784253,0.777501709,0.584351317,1.029732587,0.171133082,DB0031910013709_,1.765313766,-0.251669437,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,piperacillin,DB00319
,60589,DB00250,10013968,35,791,31,779,0.707415655,1.111831631,0.658636319,1.884764134,0.825089674,DB0025010013968_,0.192263203,0.106008773,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dapsone,DB00250
,60593,DB00250,10037844,35,791,32,778,0.803830577,1.075693991,0.639745559,1.814533249,0.893881911,DB0025010037844_,0.112181603,0.072966027,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dapsone,DB00250
,60594,DB01017,10037844,68,1401,41,860,1,1.01808119,0.674166987,1.553693467,1,DB0101710037844_,0,0.01791967,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,minocycline,DB01017
,60604,DB00557,10008531,52,5935,30,3037,0.639482164,0.886980932,0.554085129,1.443292437,0.776548875,DB0055710008531_,0.252895696,-0.119931794,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,60607,DB00758,10028334,134,8166,124,9950,0.032020037,1.316701052,1.021759442,1.697879891,0.089149134,DB0075810028334_,2.417444647,0.275129406,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,clopidogrel,DB00758
,60610,DB00758,10037660,100,8200,109,9965,0.442671208,1.114895053,0.839906372,1.47862908,0.610691868,DB0075810037660_,0.493162755,0.108760278,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,60612,DB00009,10008111,83,1268,69,1482,0.044916604,1.405732613,0.999762145,1.981697728,0.11540889,DB0000910008111_,2.159273895,0.3405586,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,alteplase,DB00009
,60622,DB00222,10033371,119,3087,61,3067,2.79372514798761e-05,1.937972374,1.405554899,2.69541715,0.00026669,DB0022210033371_,8.229423977,0.661642259,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,60624,DB00222,10047513,31,3175,20,3108,0.160715032,1.517185376,0.835610808,2.815097452,0.298512145,DB0022210047513_,1.208944661,0.416856892,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,glimepiride,DB00222
,60625,DB00758,10047513,58,8242,41,10033,0.008254575,1.721960902,1.133358654,2.637768992,0.030539105,DB0075810047513_,3.488747273,0.543463701,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,clopidogrel,DB00758
,60654,DB00864,10046571,166,6703,73,8319,2.48720551503191e-14,2.822015057,2.126162302,3.776666765,1.38508891869945e-12,DB0086410046571_,27.30525678,1.037451189,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,60655,DB01590,10046571,65,4673,17,2850,0.001221038,2.331687175,1.347446246,4.252442729,0.006487768,DB0159010046571_,5.037836773,0.846592115,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,everolimus,DB01590
,60656,DB00635,10061126,62,32991,25,23769,0.01242866,1.786739397,1.106204152,2.968302625,0.04233072,DB0063510061126_,3.162242219,0.580392393,NA,10061126,Escherichia infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,60657,DB00864,10061126,48,6821,24,8368,0.000303037,2.453468209,1.47180627,4.192394726,0.002033529,DB0086410061126_,6.197982627,0.897502619,NA,10061126,Escherichia infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,60661,DB00682,10037437,69,19390,45,16319,0.188712207,1.290472383,0.873266474,1.923810753,0.334929127,DB0068210037437_,1.093836331,0.25500834,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,60664,DB13961,10048959,252,9205,121,6293,0.00159846,1.423768678,1.1389433,1.787660683,0.008091576,DB1396110048959_,4.816931711,0.353307355,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,60669,DB00537,10013709,241,7316,206,4092,1.51789188739678e-05,0.654347072,0.538850502,0.79522192,0.000156554,DB0053710013709_,8.762109525,-0.424117378,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,60670,DB06273,10046571,67,5028,7,1403,0.00985583,2.670555781,1.223458458,6.912014724,0.035162606,DB0627310046571_,3.347772086,0.982286608,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,tocilizumab,DB06273
,60671,DB00537,10061818,52,7505,41,4257,0.129268084,0.719448401,0.467701591,1.113174183,0.254546322,DB0053710061818_,1.368272448,-0.32927047,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,60674,DB00395,10019211,130,2054,27,709,0.017884483,1.661757514,1.080275059,2.640656794,0.05660369,DB0039510019211_,2.871681095,0.507875786,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,carisoprodol,DB00395
,60675,DB00669,10019211,385,5992,58,1039,0.368132942,1.150981828,0.863950282,1.556613797,0.537845277,DB0066910019211_,0.620184349,0.140615341,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sumatriptan,DB00669
,60676,DB00956,10019211,297,5517,106,3361,1.95658939919302e-06,1.70683766,1.356865809,2.160378167,2.59782545803544e-05,DB0095610019211_,10.55825073,0.534642337,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,60677,DB01225,10019211,135,4909,60,4580,1.01598274553953e-06,2.099044146,1.533166303,2.902746285,1.45160817737144e-05,DB0122510019211_,11.14025344,0.741482073,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,enoxaparin,DB01225
,60681,DB00316,10027201,39,65435,15,36938,0.256575807,1.46769223,0.790914873,2.866375062,0.417410107,DB0031610027201_,0.873686071,0.383691256,NA,10027201,Meningitis aseptic,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,60692,DB08908,10003658,43,10630,8,3271,0.245838522,1.653865083,0.767608215,4.076781035,0.404739316,DB0890810003658_,0.904512083,0.503115023,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,dimethyl fumarate,DB08908
,60693,DB06228,10007617,26,15886,43,16033,0.053248578,0.610259056,0.359794562,1.016515798,0.131101432,DB0622810007617_,2.031783968,-0.49387173,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,60694,DB06228,10008469,81,15831,35,16041,1.48348100290822e-05,2.34504224,1.558115704,3.595018823,0.000153517,DB0622810008469_,8.781699757,0.852303415,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,60700,DB01109,10055798,86,4326,111,4159,0.043643342,0.744893983,0.553598426,0.999489161,0.112893144,DB0110910055798_,2.181313539,-0.294513375,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,heparin,DB01109
,60701,DB09153,10055798,37,7762,33,5666,0.399280543,0.8184643,0.497282094,1.352313618,0.569132565,DB0915310055798_,0.563641893,-0.200325499,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,sodium chloride,DB09153
,60703,DB08868,10028411,71,9131,17,2494,0.697022654,1.140728975,0.663396269,2.070087666,0.817711743,DB0886810028411_,0.201245397,0.13166751,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fingolimod,DB08868
,60712,DB00531,10042772,77,7175,39,6477,0.003614084,1.782209807,1.195421716,2.695571522,0.015722641,DB0053110042772_,4.152653528,0.577854059,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,60718,DB00635,10013538,121,32932,59,23735,0.015232781,1.478090901,1.073599543,2.05445834,0.049915058,DB0063510013538_,2.997432549,0.390751323,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,prednisone,DB00635
,60722,DB00316,10039073,455,65019,79,36874,5.40988578432719e-28,3.266322477,2.566371493,4.203352657,1.04943799144679e-25,DB0031610039073_,57.51637255,1.183664727,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,60724,DB00795,10039073,210,4359,58,1445,0.246954993,1.200209698,0.887582894,1.644398443,0.40608145,DB0079510039073_,0.901201523,0.18249629,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfasalazine,DB00795
,60726,DB01224,10001540,43,8065,20,5897,0.097695247,1.571994393,0.903852119,2.823912194,0.2074416,DB0122410001540_,1.572905426,0.452345127,NA,10001540,Akathisia,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,60727,DB01224,10013916,50,8058,33,5884,0.738317847,1.106393919,0.697835917,1.775165185,0.849334706,DB0122410013916_,0.163301934,0.101106006,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,60731,DB00451,10018985,47,47224,22,15397,0.162933791,0.696548579,0.411342072,1.214189513,0.301270776,DB0045110018985_,1.199745832,-0.36161774,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,60739,DB00005,10049414,61,128021,39,42380,0.001697631,0.517812358,0.340822503,0.79505934,0.008496237,DB0000510049414_,4.768131881,-0.658142346,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,60740,DB00331,10009033,110,24836,84,20668,0.564146763,1.089787503,0.812358517,1.466347587,0.715994189,DB0033110009033_,0.334083228,0.085982726,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,60741,DB00335,10009033,30,8436,31,5434,0.06667539,0.623407643,0.364086571,1.066002176,0.155362141,DB0033510009033_,1.861996496,-0.472554652,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atenolol,DB00335
,60742,DB00736,10009033,65,10526,37,5516,0.677177022,0.920609758,0.604809042,1.420039198,0.804245873,DB0073610009033_,0.217850245,-0.082719048,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,60743,DB00188,10013968,193,7693,241,8587,0.262641689,0.893908823,0.733947714,1.087539986,0.42440841,DB0018810013968_,0.857059056,-0.112151497,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bortezomib,DB00188
,60744,DB00188,10028372,44,7842,74,8754,0.033173747,0.663762194,0.445721295,0.978167187,0.091665906,DB0018810028372_,2.389604763,-0.409831336,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,bortezomib,DB00188
,60747,DB00316,10009944,43,65431,18,36935,0.350585456,1.348494717,0.761416176,2.484360038,0.520291263,DB0031610009944_,0.653366503,0.298988946,NA,10009944,Colon cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,60756,DB06605,10018836,99,13974,92,12941,1,0.996539395,0.741849425,1.339734902,1,DB0660510018836_,0,-0.003466607,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,60758,DB00682,10022052,53,19406,25,16339,0.016628836,1.784914386,1.089300026,2.999143897,0.053437124,DB0068210022052_,2.929249576,0.579370451,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,60760,DB00682,10022061,67,19392,11,16353,3.8846961322004e-09,5.136135854,2.693601864,10.78286673,9.56079005944639e-08,DB0068210022061_,16.16301038,1.636301017,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,60771,DB00108,10022437,63,10131,17,3278,0.601863032,1.199060518,0.691808007,2.189157819,0.746048066,DB0010810022437_,0.292965249,0.181538348,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,natalizumab,DB00108
,60772,DB00582,10037660,73,1057,82,1492,0.179814317,1.256497975,0.894620475,1.762123816,0.323632971,DB0058210037660_,1.128145212,0.228328466,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,voriconazole,DB00582
,60773,DB00060,10048592,86,9422,13,2452,0.079387886,1.721505994,0.953359916,3.369321253,0.177396122,DB0006010048592_,1.72937007,0.543199486,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,60778,DB13961,10042458,46,9411,18,6396,0.054756656,1.736772391,0.986664558,3.185705701,0.133932046,DB1396110042458_,2.010422731,0.552028443,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,fish oil,DB13961
,60779,DB00091,10013710,50,5460,45,2625,0.002821214,0.534208662,0.348917048,0.820037936,0.012854152,DB0009110013710_,4.354088373,-0.626968764,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,60780,DB00688,10013710,87,6403,128,5250,3.00608171330065e-05,0.557330631,0.418414455,0.73946409,0.00028438,DB0068810013710_,8.16520077,-0.584596622,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,60782,DB00864,10013710,174,6695,334,8058,6.99231329829014e-07,0.627037641,0.51749438,0.757665167,1.04457490790313e-05,DB0086410013710_,11.46931545,-0.466748706,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,60783,DB00959,10013710,66,8012,36,4966,0.609323702,1.136353358,0.744743363,1.75903723,0.75180301,DB0095910013710_,0.285280944,0.127824327,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,60796,DB00091,10035664,119,5391,72,2598,0.138077681,0.796542091,0.587147772,1.086909349,0.267042296,DB0009110035664_,1.32034822,-0.227475307,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cyclosporine,DB00091
,60797,DB00252,10035664,41,2191,28,1880,0.39485693,1.25636874,0.755072771,2.118408544,0.564725871,DB0025210035664_,0.57141485,0.228225608,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,phenytoin,DB00252
,60798,DB00688,10035664,167,6323,193,5185,0.00148746,0.709580927,0.571395939,0.880434798,0.007637051,DB0068810035664_,4.874743807,-0.343080726,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,60799,DB00864,10035664,174,6695,249,8143,0.112695404,0.849940577,0.69432139,1.038664048,0.23013146,DB0086410035664_,1.46910457,-0.162588842,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,60800,DB00252,10013573,66,2166,57,1851,1,0.989504105,0.679693751,1.444325554,1,DB0025210013573_,0,-0.010551366,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,phenytoin,DB00252
,60812,DB00316,10066901,121,65353,61,36892,0.488031176,1.119767499,0.816272513,1.549818508,0.651642045,DB0031610066901_,0.428259879,0.113121073,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,60813,DB00338,10066901,72,33602,49,22223,0.925984452,0.971779213,0.666396637,1.427585056,0.968466549,DB0033810066901_,0.032041335,-0.028626647,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,60814,DB00451,10066901,75,47196,20,15399,0.475564893,1.223531709,0.738877335,2.116767544,0.64116317,DB0045110066901_,0.444471299,0.20174152,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,60821,DB01217,10016256,323,2431,19,249,0.020060933,1.740977997,1.072558345,2.983513783,0.061915297,DB0121710016256_,2.781988002,0.554447022,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,anastrozole,DB01217
,60823,DB00635,10036018,82,32971,53,23741,0.600437303,1.114079471,0.778837211,1.605521527,0.744843763,DB0063510036018_,0.294580796,0.108028478,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,60843,DB00973,10002855,55,3796,32,2989,0.192634508,1.353297233,0.857354728,2.168605866,0.33995979,DB0097310002855_,1.078927933,0.30254401,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ezetimibe,DB00973
,60846,DB00542,10033371,61,1625,34,1390,0.047547269,1.53445043,0.98607314,2.42314959,0.120478139,DB0054210033371_,2.116286963,0.428172291,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,benazepril,DB00542
,60847,DB00973,10033371,133,3718,75,2946,0.022999268,1.405050843,1.046231431,1.898565948,0.068900815,DB0097310033371_,2.675087278,0.340073489,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,60853,DB01610,10029354,51,890,37,1181,0.006018783,1.828505862,1.162856255,2.899229612,0.023722254,DB0161010029354_,3.741341701,0.603499165,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,valganciclovir,DB01610
,60855,DB01610,10059866,20,921,45,1173,0.041492963,0.566193994,0.314370488,0.986684094,0.108731695,DB0161010059866_,2.218871944,-0.568818515,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,valganciclovir,DB01610
,60859,DB00285,10015150,65,10886,15,3703,0.198129367,1.473960034,0.830244144,2.786525082,0.346795659,DB0028510015150_,1.059019553,0.387952679,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,venlafaxine,DB00285
,60860,DB00567,10015150,66,4453,27,2054,0.654072377,1.127504132,0.708100859,1.841539562,0.787950521,DB0056710015150_,0.238319981,0.120006457,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,cephalexin,DB00567
,60861,DB00736,10015150,93,10498,31,5522,0.028781976,1.577973403,1.039327688,2.455555005,0.081995799,DB0073610015150_,2.501087259,0.456141368,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,esomeprazole,DB00736
,60863,DB01156,10015150,67,13555,20,6308,0.083846118,1.558935365,0.933360758,2.715130609,0.184820765,DB0115610015150_,1.688368762,0.44400313,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,bupropion,DB01156
,60864,DB01409,10015150,39,5992,21,3945,0.509583766,1.222655832,0.70059886,2.191277473,0.670157263,DB0140910015150_,0.400242874,0.201025405,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,tiotropium,DB01409
,60866,DB06228,10015150,63,15849,37,16039,0.008959525,1.723074887,1.129690508,2.66203415,0.032596373,DB0622810015150_,3.423554262,0.544110419,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,rivaroxaban,DB06228
,60868,DB01020,10033425,49,1764,39,1839,0.235581855,1.309728535,0.837889383,2.059527611,0.392736035,DB0102010033425_,0.934617559,0.269819891,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,isosorbide mononitrate,DB01020
,60869,DB01238,10033425,76,5174,21,3481,0.00015161,2.434615123,1.482219947,4.165165634,0.001137619,DB0123810033425_,6.778817901,0.889788684,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,aripiprazole,DB01238
,60871,DB00264,10042674,219,29388,113,24779,1.93027640204542e-05,1.634084111,1.295492005,2.070565063,0.000193543,DB0026410042674_,8.550010498,0.491082471,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,60873,DB01409,10042674,56,5975,30,3936,0.378345599,1.229613258,0.774107735,1.988573736,0.548333314,DB0140910042674_,0.60087194,0.206699696,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,60875,DB06228,10042674,99,15813,43,16033,1.84389223298838e-06,2.334413044,1.615069445,3.423957585,2.46587165322307e-05,DB0622810042674_,10.61038011,0.847760486,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,60887,DB08877,10002855,31,3258,19,3210,0.118287842,1.607416967,0.877746391,3.018251929,0.238669806,DB0887710002855_,1.432674246,0.474628522,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ruxolitinib,DB08877
,60894,DB00313,10001497,26,1213,54,1463,0.022866635,0.580826366,0.34689324,0.950345223,0.068581641,DB0031310001497_,2.679730403,-0.543303421,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,valproic acid,DB00313
,60895,DB01018,10001497,8,404,55,724,0.00010286,0.260893447,0.10625252,0.558124784,0.000817561,DB0101810001497_,7.109184882,-1.343643205,male,10001497,Agitation,10037175,Psychiatric disorders,Psych,guanfacine,DB01018
,60902,DB00313,10070863,178,1061,217,1300,1,1.005049835,0.806161793,1.251902007,1,DB0031310070863_,0,0.005037128,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,valproic acid,DB00313
,60905,DB00243,10013968,73,1181,85,1541,0.509584676,1.120569543,0.800477303,1.565524103,0.670157263,DB0024310013968_,0.400242874,0.113837077,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranolazine,DB00243
,60907,DB00421,10013709,295,8608,143,5109,0.050178634,1.224338203,0.996200829,1.510393688,0.125351206,DB0042110013709_,2.076635835,0.202400456,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,60908,DB00612,10013709,69,1071,24,616,0.045119059,1.65316,1.013342729,2.781370232,0.115810211,DB0061210013709_,2.155802542,0.502688608,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,bisoprolol,DB00612
,60909,DB13867,10013709,167,4383,101,2453,0.559466931,0.925393638,0.714773555,1.20291246,0.712186759,DB1386710013709_,0.339415101,-0.077536077,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,60912,DB00404,10000087,247,19645,78,9784,0.000363677,1.57710491,1.21646938,2.063946629,0.002368497,DB0040410000087_,6.045499713,0.455590831,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,60918,DB01076,10055798,108,25639,150,25433,0.008634009,0.714222878,0.552148057,0.92138003,0.031658635,DB0107610055798_,3.452744343,-0.336560211,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,atorvastatin,DB01076
,60919,DB00051,10000269,51,25680,34,11386,0.076777391,0.665077267,0.422340508,1.059270116,0.172831231,DB0005110000269_,1.755439702,-0.407852054,NA,10000269,Abscess,10021881,Infections and infestations,Infec,adalimumab,DB00051
,60920,DB00051,10017944,171,25560,47,11373,0.003131688,1.618852676,1.165145372,2.287864763,0.014012498,DB0005110017944_,4.267805658,0.481717674,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,60921,DB00051,10030095,57,25674,14,11406,0.052532019,1.808758216,0.994581072,3.516472639,0.129768726,DB0005110030095_,2.042001444,0.592640542,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,60923,DB00051,10040943,57,25674,23,11397,0.808445236,1.100125082,0.666746426,1.872020804,0.896604841,DB0005110040943_,0.109140048,0.095423885,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,60927,DB00734,10012239,28,4022,47,4855,0.199841592,0.719157077,0.432830673,1.174875311,0.348811804,DB0073410012239_,1.053222745,-0.329675479,NA,10012239,Delusion,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,60928,DB00472,10013496,43,10716,21,4291,0.488401634,0.819965552,0.475371871,1.456365054,0.651954546,DB0047210013496_,0.427780434,-0.198492949,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,60931,DB00619,10013573,45,2854,55,2439,0.085162329,0.699263031,0.45903024,1.060371752,0.187047571,DB0061910013573_,1.676392303,-0.357728311,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,imatinib,DB00619
,60932,DB00734,10013573,65,3985,67,4835,0.378691861,1.177057618,0.821465826,1.685713806,0.548689138,DB0073410013573_,0.600223232,0.163017781,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,60933,DB00472,10013709,528,10231,181,4131,0.067126415,1.177833638,0.989021984,1.407775998,0.15619846,DB0047210013709_,1.8566279,0.163676851,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,60936,DB00619,10016256,190,2709,159,2335,0.824347613,1.029992698,0.823708687,1.289218496,0.906970428,DB0061910016256_,0.097645434,0.029551713,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,60944,DB00472,10061920,21,10738,40,4272,3.28920202520254e-09,0.208889788,0.116878313,0.363309327,8.24181842063381e-08,DB0047210061920_,16.31145974,-1.565948497,male,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,60946,DB00734,10061920,66,3984,85,4817,0.741850011,0.938810905,0.66821694,1.31420026,0.852065874,DB0073410061920_,0.160091438,-0.063141199,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,60948,DB08932,10029216,84,19359,16,6581,0.037266102,1.784583923,1.036603495,3.267039507,0.100101117,DB0893210029216_,2.301574429,0.579185292,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,macitentan,DB08932
,60950,DB08932,10008469,491,18952,103,6494,3.3933564828677e-06,1.633484665,1.315657178,2.044044657,4.20628979732032e-05,DB0893210008469_,10.07634449,0.490715564,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,60956,DB00398,10028813,82,645,167,1371,0.773738874,1.043670876,0.778201153,1.391492134,0.876475018,DB0039810028813_,0.131847077,0.042744187,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sorafenib,DB00398
,60959,DB09053,10002034,60,2225,113,3939,0.748399733,0.940005834,0.672522841,1.302820409,0.857130893,DB0905310002034_,0.154164638,-0.061869197,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ibrutinib,DB09053
,60960,DB09053,10021097,30,2255,67,3985,0.337636921,0.791288498,0.494941036,1.238678384,0.506817609,DB0905310021097_,0.679604085,-0.234092653,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ibrutinib,DB09053
,60963,DB00005,10024453,104,127978,28,42391,0.365488294,1.230299516,0.803867579,1.940485918,0.535124288,DB0000510024453_,0.625256245,0.207257648,NA,10024453,Ligament sprain,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,60970,DB00768,10020751,45,1870,7,677,0.037494732,2.326767825,1.034891837,6.145231791,0.100581624,DB0076810020751_,2.296785702,0.844480105,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,olopatadine,DB00768
,60972,DB08932,10037844,380,19063,93,6504,0.00391559,1.394040202,1.10643911,1.771466876,0.01677745,DB0893210037844_,4.087719527,0.332206151,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,macitentan,DB08932
,60974,DB06703,10037087,144,631,60,351,0.089726755,1.334707014,0.952189209,1.887579131,0.194777862,DB0670310037087_,1.635895536,0.288711803,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,gadobutrol,DB06703
,60975,DB08931,10002034,288,6289,59,2387,8.3549537440322e-06,1.852616807,1.389753509,2.505262423,9.2897613858666e-05,DB0893110002034_,9.284012598,0.61659913,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,riociguat,DB08931
,60977,DB00555,10013887,51,6996,39,3447,0.042773877,0.644327106,0.415476302,1.006209479,0.111274314,DB0055510013887_,2.195756825,-0.439548754,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,60979,DB00335,10006093,81,8385,57,5408,0.661483372,0.916530691,0.64392561,1.312060177,0.793526116,DB0033510006093_,0.231268828,-0.087159725,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,atenolol,DB00335
,60980,DB01275,10006093,46,3933,22,3327,0.027725676,1.76860349,1.040047394,3.094120331,0.079629523,DB0127510006093_,2.530370364,0.570190247,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,hydralazine,DB01275
,60986,DB00297,10060938,117,1555,36,843,0.003645898,1.761538337,1.190623743,2.661178937,0.015830914,DB0029710060938_,4.145790663,0.566187482,NA,10060938,Anaesthetic complication,10022117,"Injury, poisoning and procedural complications",Inj&P,bupivacaine,DB00297
,60988,DB08865,10035664,43,1168,27,944,0.330297983,1.287015946,0.770783663,2.18353445,0.499001781,DB0886510035664_,0.695145614,0.252326318,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,crizotinib,DB08865
,60989,DB00451,10001497,157,47114,76,15343,0.00592835,0.672743598,0.508044693,0.897354297,0.023443881,DB0045110001497_,3.753145755,-0.396391005,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,60991,DB05259,10053425,514,10756,92,2636,0.00544152,1.369170633,1.090014646,1.735731252,0.021886816,DB0525910053425_,3.821870842,0.314205179,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,60992,DB00331,10020937,228,24718,152,20600,0.033948774,1.250093899,1.012803918,1.546510546,0.093297456,DB0033110020937_,2.371962442,0.223218668,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,metformin,DB00331
,60993,DB00727,10020937,49,3794,26,4147,0.002478995,2.059765366,1.252444987,3.460202547,0.011590249,DB0072710020937_,4.457591166,0.722592076,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,60994,DB09270,10020937,60,3054,18,2350,0.000300228,2.564500557,1.488816072,4.628235563,0.002018798,DB0927010020937_,6.205252973,0.941763745,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,ubidecarenone,DB09270
,60995,DB00727,10033425,104,3739,85,4088,0.055182083,1.337678617,0.991068332,1.809637291,0.134651045,DB0072710033425_,2.005068696,0.290935736,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,nitroglycerin,DB00727
,60996,DB09270,10033425,116,2998,45,2323,6.75464646869686e-05,1.997130482,1.397534703,2.896900721,0.000569559,DB0927010033425_,7.470648402,0.691711391,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ubidecarenone,DB09270
,60997,DB00398,10001760,47,680,35,1503,1.70117890366258e-06,2.966519615,1.855645975,4.781883363,2.30017939726188e-05,DB0039810001760_,10.67993835,1.087389419,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,sorafenib,DB00398
,61000,DB00398,10040844,27,700,52,1486,0.713302119,1.102200564,0.659590405,1.804778151,0.829846911,DB0039810040844_,0.186514039,0.097308694,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,sorafenib,DB00398
,61003,DB00007,10012735,29,1918,142,4310,6.57740754441437e-05,0.458968593,0.295555803,0.690936343,0.000556534,DB0000710012735_,7.493783044,-0.778773497,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,leuprolide,DB00007
,61005,DB06605,10060933,236,13837,191,12842,0.171690873,1.146745214,0.942079152,1.397330015,0.313015057,DB0660510060933_,1.161503984,0.136927681,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,61006,DB00635,10067973,22,33031,34,23760,0.006188959,0.465446441,0.25924427,0.819464751,0.02426201,DB0063510067973_,3.718843535,-0.764758246,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,prednisone,DB00635
,61007,DB00682,10067973,42,19417,22,16342,0.078550804,1.606730238,0.937165567,2.82741024,0.175920364,DB0068210067973_,1.737723864,0.474201206,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,61009,DB00635,10011831,99,32954,110,23684,0.001931067,0.646847637,0.487709606,0.856927225,0.009462173,DB0063510011831_,4.66045327,-0.435644504,NA,10011831,Cytomegalovirus infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,61011,DB06403,10015150,176,21295,44,6617,0.232027493,1.242905562,0.887689083,1.77344398,0.388380605,DB0640310015150_,0.945769479,0.217451834,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,ambrisentan,DB06403
,61012,DB06403,10038687,68,21403,35,6626,0.019513325,0.601487726,0.394038767,0.932892239,0.060648899,DB0640310038687_,2.802653793,-0.50834915,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,61013,DB06403,10040829,49,21422,14,6647,0.882597018,1.08600621,0.58957103,2.131437928,0.950956636,DB0640310040829_,0.050286816,0.082506939,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,ambrisentan,DB06403
,61019,DB00635,10052140,43,33010,15,23779,0.015844372,2.064986052,1.12436586,4.002659286,0.051454081,DB0063510052140_,2.967065507,0.725123472,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,prednisone,DB00635
,61020,DB06605,10044390,90,13983,98,12935,0.272644796,0.8495438,0.630280241,1.143942905,0.435558906,DB0660510044390_,0.831125232,-0.16305578,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,61021,DB06605,10018852,93,13980,92,12941,0.658556342,0.935771277,0.693089839,1.263500658,0.791520312,DB0660510018852_,0.233799738,-0.066384195,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,apixaban,DB06605
,61023,DB00455,10015090,68,9333,27,5091,0.19571395,1.373782338,0.866544572,2.235385815,0.343907555,DB0045510015090_,1.067382392,0.317567766,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,61025,DB00758,10048561,42,8258,45,10029,0.590109167,1.13348562,0.725540597,1.767571492,0.736743033,DB0075810048561_,0.305516113,0.125297505,NA,10048561,Stent placement,10042613,Surgical and medical procedures,Surg,clopidogrel,DB00758
,61030,DB00087,10035664,51,1318,20,727,0.25528673,1.406347763,0.816341322,2.510778789,0.416008165,DB0008710035664_,0.87705039,0.340996105,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,alemtuzumab,DB00087
,61031,DB00564,10035664,42,2562,36,1427,0.073208805,0.649860866,0.404353297,1.049279321,0.166871229,DB0056410035664_,1.790532849,-0.430996992,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,carbamazepine,DB00564
,61032,DB00620,10035664,144,4684,98,3034,0.738408445,0.951800723,0.728087932,1.248457504,0.849356322,DB0062010035664_,0.163276485,-0.049399591,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,triamcinolone,DB00620
,61036,DB01610,10035664,29,912,47,1171,0.348526159,0.792334611,0.476826212,1.296833431,0.518039476,DB0161010035664_,0.657703832,-0.232771488,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,valganciclovir,DB01610
,61040,DB00126,10038695,58,10113,66,5879,0.000238727,0.510875844,0.352166546,0.739387669,0.00167042,DB0012610038695_,6.394679982,-0.671628685,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,61043,DB00741,10038695,50,4044,63,3111,0.009795254,0.610598952,0.411347694,0.902194367,0.03500112,DB0074110038695_,3.352375213,-0.493314915,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrocortisone,DB00741
,61048,DB01610,10038695,23,918,51,1167,0.031341245,0.573446767,0.331825475,0.963798612,0.087662106,DB0161010038695_,2.434265564,-0.556090168,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,valganciclovir,DB01610
,61056,DB00668,10013709,560,9531,455,3848,2.28117772416153e-25,0.496917653,0.435820824,0.566826423,3.57974665549766e-23,DB0066810013709_,51.68416511,-0.699330955,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,61059,DB01224,10028372,61,8047,32,5885,0.140562958,1.394061507,0.893259502,2.21334398,0.270624234,DB0122410028372_,1.307024009,0.332221434,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,quetiapine,DB01224
,61078,DB00465,10033371,117,1987,27,856,0.003545796,1.866458441,1.209098779,2.974466923,0.015479364,DB0046510033371_,4.168247467,0.624042753,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ketorolac,DB00465
,61079,DB00683,10033371,34,1550,24,1614,0.184643897,1.474975338,0.844947727,2.612711827,0.329731559,DB0068310033371_,1.109476414,0.38864127,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,midazolam,DB00683
,61081,DB00814,10033371,478,7809,137,3278,8.63388843893323e-05,1.464564456,1.203162128,1.792032892,0.000703804,DB0081410033371_,7.259009954,0.381557899,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,61084,DB01592,10033371,273,6003,76,2991,4.09999444317155e-06,1.789668641,1.37754304,2.348274832,4.96056865080617e-05,DB0159210033371_,9.911405083,0.582030486,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,61125,DB00904,10069868,56,23013,9,14447,1.73522284464809e-05,3.906037274,1.916734781,8.986117524,0.00017617,DB0090410069868_,8.644062886,1.362523375,female,10069868,Device issue,10077536,Product issues,Prod,ondansetron,DB00904
,61127,DB01104,10069868,58,15405,10,7276,0.001602586,2.739322785,1.387117426,6.015531196,0.008108102,DB0110410069868_,4.814891492,1.007710731,female,10069868,Device issue,10077536,Product issues,Prod,sertraline,DB01104
,61131,DB01164,10018884,18,6506,36,7900,0.09953578,0.607153487,0.324249231,1.098736476,0.210102227,DB0116410018884_,1.560161072,-0.498973659,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,calcium chloride,DB01164
,61136,DB00502,10013710,69,1325,84,1788,0.558341018,1.108427165,0.787688777,1.555474238,0.711316449,DB0050210013710_,0.340637872,0.102942042,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,haloperidol,DB00502
,61141,DB01075,10042458,54,19894,28,11069,0.818147568,1.073059041,0.66738984,1.760465272,0.902926851,DB0107510042458_,0.102113735,0.070513486,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,61143,DB00811,10038153,43,2755,34,4122,0.006814723,1.892005322,1.17536298,3.067724331,0.026231967,DB0081110038153_,3.640776504,0.637637284,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,ribavirin,DB00811
,61150,DB06605,10046735,86,13987,53,12980,0.02128795,1.505790616,1.056171324,2.164202592,0.064965192,DB0660510046735_,2.733903665,0.409318086,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,apixaban,DB06605
,61163,DB01050,10022998,68,18040,50,9321,0.064249247,0.702675106,0.480158125,1.034541046,0.151075543,DB0105010022998_,1.889975285,-0.352860648,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,61165,DB01050,10037884,82,18026,30,9341,0.11026781,1.41638525,0.921233483,2.231446818,0.226425635,DB0105010037884_,1.485338709,0.348108027,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,61166,DB00331,10056342,47,24899,34,20718,0.577459482,1.150220807,0.723948183,1.844956068,0.726502713,DB0033110056342_,0.319513061,0.13995393,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,61167,DB00722,10056342,40,25363,25,26007,0.061879016,1.640599478,0.970866173,2.822576822,0.146921091,DB0072210056342_,1.917859629,0.49506171,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,61195,DB00285,10012174,105,10846,41,3677,0.444912468,0.868246797,0.59850859,1.280584957,0.612964483,DB0028510012174_,0.489448284,-0.141279276,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,venlafaxine,DB00285
,61196,DB00706,10012174,12,1063,230,15695,0.50422915,0.770336219,0.390964238,1.377806309,0.665344538,DB0070610012174_,0.40745027,-0.260928212,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,tamsulosin,DB00706
,61203,DB00007,10046571,10,1937,79,4373,2.30579518667276e-05,0.285838305,0.131684936,0.555294649,0.000225517,DB0000710046571_,8.397112824,-1.252328994,male,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,leuprolide,DB00007
,61204,DB00285,10046571,172,10779,42,3676,0.05716725,1.396554344,0.989390934,2.010872365,0.138116748,DB0028510046571_,1.97965595,0.33400802,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,venlafaxine,DB00285
,61205,DB00761,10046571,448,14859,122,8503,2.64044456890673e-14,2.101299945,1.713189412,2.593230014,1.46576738107103e-12,DB0076110046571_,27.2486422,0.742556175,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,61206,DB01050,10046571,303,17805,92,9279,3.01158567096378e-06,1.716350887,1.35296334,2.194713761,3.80300405290814e-05,DB0105010046571_,10.17713417,0.54020046,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,61207,DB01112,10046571,32,1113,21,558,0.375984171,0.764108351,0.422741869,1.408151475,0.545751989,DB0111210046571_,0.60559064,-0.26904568,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,cefuroxime,DB01112
,61218,DB08932,10007554,329,19114,123,6474,0.353970617,0.905959223,0.732785716,1.125988129,0.523844211,DB0893210007554_,0.646560946,-0.098760982,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,macitentan,DB08932
,61225,DB01076,10047461,68,25679,54,25529,0.23882283,1.251895424,0.862553345,1.824812845,0.396541997,DB0107610047461_,0.924973325,0.224658742,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,61226,DB01373,10047461,78,22642,19,7362,0.288588233,1.334791078,0.799810338,2.336226,0.453626463,DB0137310047461_,0.790481188,0.288774784,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,calcium,DB01373
,61234,DB00175,10046735,74,8057,40,6066,0.105955726,1.392805474,0.93420259,2.10363859,0.220126956,DB0017510046735_,1.513550826,0.33132004,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,pravastatin,DB00175
,61235,DB00051,10014011,63,25668,17,11403,0.069133777,1.64631697,0.950956645,3.002675621,0.159787323,DB0005110014011_,1.833911578,0.498540654,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,adalimumab,DB00051
,61236,DB00158,10014011,61,16754,18,8086,0.070988558,1.635553368,0.953097045,2.942800416,0.163013011,DB0015810014011_,1.81392526,0.491981199,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,folic acid,DB00158
,61237,DB00451,10014011,132,47139,29,15390,0.054207617,1.486010834,0.98772872,2.305820198,0.132852886,DB0045110014011_,2.01851288,0.396095237,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,61238,DB00563,10014011,118,46528,19,15329,0.002760521,2.045961702,1.253364578,3.520313631,0.012627967,DB0056310014011_,4.371841289,0.715867949,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,61240,DB00051,10042209,96,25635,32,11388,0.179142367,1.332650213,0.884349767,2.056850521,0.32281517,DB0005110042209_,1.130675349,0.287169601,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,adalimumab,DB00051
,61243,DB06273,10002198,57,5038,16,1394,1,0.985735093,0.556134872,1.844980338,1,DB0627310002198_,0,-0.014367629,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,tocilizumab,DB06273
,61246,DB00295,10008469,66,14597,28,9574,0.056974023,1.545994567,0.978921502,2.500798023,0.13774393,DB0029510008469_,1.982358897,0.435667436,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,61247,DB00327,10008469,38,6100,14,4248,0.04695257,1.890096335,0.999572522,3.781869421,0.119362473,DB0032710008469_,2.125590424,0.636627799,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,61248,DB00433,10008469,40,7616,29,5991,0.808300281,1.085029405,0.65521261,1.817065593,0.896538648,DB0043310008469_,0.109213877,0.081607088,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,61249,DB00472,10008469,64,10695,23,4289,0.721921738,1.115895159,0.682303903,1.885968379,0.836155498,DB0047210008469_,0.178940681,0.109656916,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,61251,DB00813,10008469,44,10528,19,10149,0.003372566,2.232207505,1.275491171,4.051027703,0.014863831,DB0081310008469_,4.208824464,0.802991008,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,61253,DB00904,10008469,186,22883,55,14401,2.50323882462312e-07,2.128240875,1.566335148,2.932432429,4.15651500348823e-06,DB0090410008469_,12.39083357,0.755295758,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,61254,DB00996,10008469,205,38748,83,22342,0.006854798,1.42411832,1.097745637,1.861634275,0.026369723,DB0099610008469_,3.635538775,0.353552899,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,61255,DB01137,10008469,43,7729,20,5573,0.124088508,1.55020772,0.891269804,2.784938528,0.247208309,DB0113710008469_,1.397523943,0.438388935,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,61261,DB00813,10008531,65,10507,35,10133,0.0049301,1.790978889,1.168716569,2.786254294,0.020246491,DB0081310008531_,3.899773779,0.582762336,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,61262,DB00868,10008531,39,2945,16,1630,0.395225864,1.349025386,0.73396584,2.594294387,0.564978732,DB0086810008531_,0.570967192,0.299382395,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,benzonatate,DB00868
,61267,DB00327,10012378,112,6026,40,4222,0.000171132,1.961638202,1.352759936,2.896106812,0.00126461,DB0032710012378_,6.672991819,0.673779942,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,hydromorphone,DB00327
,61268,DB00433,10012378,82,7574,51,5969,0.189361387,1.267103823,0.881063237,1.837450767,0.335735052,DB0043310012378_,1.091432967,0.236733842,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,prochlorperazine,DB00433
,61269,DB00813,10012378,125,10447,63,10105,1.8763496434609e-05,1.91910498,1.404809885,2.644178689,0.000188856,DB0081310012378_,8.574523589,0.651858921,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,fentanyl,DB00813
,61270,DB00868,10012378,40,2944,15,1631,0.256503642,1.477238021,0.795517725,2.887964561,0.417331449,DB0086810012378_,0.873874532,0.390174142,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,benzonatate,DB00868
,61271,DB01137,10012378,95,7677,50,5543,0.07555994,1.371818309,0.962252216,1.976326411,0.170722944,DB0113710012378_,1.767713249,0.316137093,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,levofloxacin,DB01137
,61283,DB00904,10016750,37,23032,18,14438,0.408444927,1.288533262,0.714963511,2.40523806,0.577839818,DB0090410016750_,0.54845858,0.253504565,NA,10016750,Flank pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,61289,DB00433,10021015,83,7573,28,5992,4.70794816968556e-05,2.345259616,1.509521642,3.745207084,0.000419771,DB0043310021015_,7.775801825,0.852396106,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,prochlorperazine,DB00433
,61292,DB00813,10021015,53,10519,33,10135,0.051714662,1.547391332,0.982582045,2.469505448,0.128274267,DB0081310021015_,2.053584595,0.436570502,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,fentanyl,DB00813
,61294,DB00904,10021015,199,22870,93,14363,0.018551374,1.34383442,1.044432728,1.739725873,0.058233789,DB0090410021015_,2.843289527,0.295527035,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,61299,DB00868,10033371,108,2876,36,1610,0.007756481,1.679241874,1.135657246,2.534570409,0.029056624,DB0086810033371_,3.538508817,0.518342426,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,benzonatate,DB00868
,61301,DB06589,10033371,52,1978,50,2603,0.129635133,1.368505579,0.90589271,2.069229018,0.25514485,DB0658910033371_,1.365923856,0.313719326,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,pazopanib,DB06589
,61303,DB00472,10037660,161,10598,65,4247,0.941026734,0.992592631,0.737996727,1.348300761,0.980220643,DB0047210037660_,0.019977587,-0.00743494,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,61305,DB00868,10037660,93,2891,34,1612,0.038482492,1.525049086,1.014153538,2.341762133,0.102603062,DB0086810037660_,2.2768875,0.422026597,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,benzonatate,DB00868
,61310,DB00433,10046571,178,7478,57,5963,2.78216191164475e-10,2.489932485,1.834291406,3.424197608,8.47873922870518e-09,DB0043310046571_,18.58570407,0.912255596,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,61311,DB00868,10046571,60,2924,19,1627,0.032688564,1.756950529,1.029741242,3.1291695,0.090591902,DB0086810046571_,2.40139045,0.563579652,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,benzonatate,DB00868
,61330,DB01015,10006451,106,9781,51,9330,5.32356856042416e-05,1.982518376,1.404834753,2.829469345,0.00046589,DB0101510006451_,7.671561445,0.684367944,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,61331,DB01373,10006451,279,22441,49,7332,2.50797571543652e-05,1.860189557,1.367448979,2.577616091,0.000242183,DB0137310006451_,8.325817995,0.620678395,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,calcium,DB01373
,61334,DB01015,10013968,345,9542,307,9074,0.425400891,1.068686767,0.911115263,1.253848786,0.594153002,DB0101510013968_,0.520618414,0.066430574,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,61335,DB00203,10017944,124,13754,49,8889,0.003692278,1.635460976,1.164617843,2.328140448,0.015995308,DB0020310017944_,4.135459819,0.491924707,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,61337,DB00635,10017944,190,32863,70,23724,7.34157688083853e-07,1.959425783,1.481498448,2.616975905,1.08870718371137e-05,DB0063510017944_,11.42793454,0.672651463,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,61338,DB00695,10017944,111,27938,69,20459,0.291197709,1.178027314,0.864044529,1.615757728,0.456608708,DB0069510017944_,0.783928473,0.163841272,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,61339,DB00736,10017944,55,10536,18,5535,0.084408174,1.605167126,0.927117847,2.907732998,0.185732606,DB0073610017944_,1.683447243,0.473227879,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,61340,DB01015,10017944,44,9843,39,9342,0.826018068,1.070805638,0.679211038,1.693793268,0.908162079,DB0101510017944_,0.096332415,0.068411298,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,61342,DB00736,10021143,43,10548,36,5517,0.043047097,0.624737147,0.391387861,1.002546846,0.111768949,DB0073610021143_,2.191321497,-0.470424283,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,61343,DB00761,10021143,215,15092,117,8508,0.773883984,1.035937229,0.821907049,1.311035875,0.876601616,DB0076110021143_,0.131702647,0.035306552,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,61344,DB01015,10021143,75,9812,88,9293,0.181509689,0.807203226,0.584376912,1.112600465,0.325775498,DB0101510021143_,1.12154679,-0.214179814,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,61345,DB01373,10021143,83,22637,28,7353,0.825925114,0.962864543,0.620099522,1.536565644,0.908097866,DB0137310021143_,0.096403124,-0.037842538,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,61349,DB01015,10022611,51,9836,11,9370,5.86476061580738e-07,4.416240911,2.271217239,9.405345232,8.92102041588525e-06,DB0101510022611_,11.62710022,1.485288862,female,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,61351,DB00203,10036790,215,13663,64,8874,9.92345863197014e-09,2.181808712,1.641086648,2.935372116,2.2360746690213e-07,DB0020310036790_,15.3133737,0.780154217,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,61353,DB00736,10036790,46,10545,19,5534,0.433583455,1.270590102,0.729090728,2.298608063,0.602078352,DB0073610036790_,0.50736769,0.23948144,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,61354,DB01015,10036790,29,9858,33,9348,0.525363718,0.833333431,0.487714683,1.41685411,0.683424684,DB0101510036790_,0.38063882,-0.18232144,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,61355,DB00264,10047924,103,29504,60,24832,0.027167958,1.444817393,1.040419533,2.021882091,0.078378858,DB0026410047924_,2.546201056,0.367982942,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,61357,DB00559,10047924,74,9585,15,3291,0.066731825,1.693711791,0.961948701,3.182265043,0.15544451,DB0055910047924_,1.861466463,0.526922447,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,61358,DB00695,10047924,177,27872,79,20449,0.000220372,1.643783602,1.25312074,2.172517675,0.00156342,DB0069510047924_,6.460879477,0.497000659,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,61359,DB00761,10047924,87,15220,31,8594,0.027009548,1.584638995,1.039790796,2.473349241,0.078041769,DB0076110047924_,2.550511096,0.460356618,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,61360,DB01015,10047924,45,9842,32,9349,0.25319094,1.335785399,0.829525006,2.173844744,0.413605784,DB0101510047924_,0.882841971,0.289519433,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,61383,DB00005,10018627,78,128004,64,42355,1.64035015957326e-07,0.403271414,0.285983507,0.570433915,2.84222834175236e-06,DB0000510018627_,12.77092219,-0.90814546,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,etanercept,DB00005
,61384,DB00115,10018627,40,18385,41,10431,0.010382873,0.553566447,0.3487336,0.878004367,0.036681486,DB0011510018627_,3.30548311,-0.591373485,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,cyanocobalamin,DB00115
,61385,DB00169,10018627,77,38614,48,18127,0.125144987,0.753039602,0.518224203,1.104040898,0.248841516,DB0016910018627_,1.390939069,-0.283637461,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,61388,DB00331,10018627,39,24907,42,20710,0.264721059,0.772109728,0.486080522,1.223823363,0.426665708,DB0033110018627_,0.851754459,-0.258628604,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,61389,DB00338,10018627,59,33615,61,22211,0.015099629,0.639106685,0.438952965,0.929891499,0.049589265,DB0033810018627_,3.003980906,-0.447683882,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,61390,DB00381,10018627,65,29295,78,22809,0.011140325,0.648846393,0.459322341,0.913947428,0.038797407,DB0038110018627_,3.249401855,-0.432559273,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,61396,DB00695,10018627,99,27950,125,20403,5.7528519095807e-05,0.578165281,0.439312177,0.759201518,0.000497659,DB0069510018627_,7.605595287,-0.547895497,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,61397,DB00761,10018627,42,15265,36,8589,0.075730119,0.656418113,0.410183204,1.055428995,0.171025533,DB0076110018627_,1.765942418,-0.420957326,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,61405,DB00115,10037153,201,18224,49,10423,1.35201002368652e-08,2.346049438,1.70755748,3.278386466,2.95040128456622e-07,DB0011510037153_,15.03615446,0.852732823,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,61406,DB00169,10037153,436,38255,133,18042,7.24813148271846e-06,1.546066688,1.269281025,1.893373021,8.18287118865314e-05,DB0016910037153_,9.410882375,0.435714085,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,61407,DB00177,10037153,68,4732,27,2823,0.087038236,1.502413119,0.946427298,2.447554185,0.190119254,DB0017710037153_,1.660103753,0.407072562,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,valsartan,DB00177
,61408,DB00285,10037153,132,10819,21,3697,0.00051949,2.147924675,1.346404854,3.59078291,0.003185907,DB0028510037153_,5.749018215,0.764502108,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,venlafaxine,DB00285
,61409,DB00381,10037153,234,29126,156,22731,0.137387035,1.170645494,0.951152391,1.444075354,0.266068759,DB0038110037153_,1.324000512,0.157555301,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,61411,DB00443,10037153,169,1977,97,1093,0.789749195,0.96326485,0.737486985,1.263537386,0.886076516,DB0044310037153_,0.120951971,-0.037426879,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,betamethasone,DB00443
,61412,DB00471,10037153,209,13980,50,5415,0.001657858,1.619084173,1.182093827,2.254601503,0.008338461,DB0047110037153_,4.786876564,0.481860664,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,61413,DB00656,10037153,143,11870,47,6572,0.001714595,1.684510267,1.201984126,2.398206365,0.008569715,DB0065610037153_,4.759520776,0.521474879,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,trazodone,DB00656
,61414,DB00695,10037153,172,27877,94,20434,0.024877964,1.341235461,1.036410797,1.744692125,0.073227021,DB0069510037153_,2.614190791,0.293591175,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,61415,DB00761,10037153,57,15250,15,8610,0.006590022,2.145380038,1.197578164,4.082752719,0.025516496,DB0076110037153_,3.668430144,0.763316711,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,potassium chloride,DB00761
,61416,DB00864,10037153,36,6833,26,8366,0.041044734,1.69517387,0.994399302,2.92696184,0.107746013,DB0086410037153_,2.227978557,0.527785314,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,tacrolimus,DB00864
,61435,DB00959,10019974,46,8032,23,4979,0.456915636,1.239740828,0.735166136,2.145661644,0.624287256,DB0095910019974_,0.47114467,0.214902348,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,61437,DB00959,10028372,107,7971,63,4939,0.811750249,1.052373435,0.762134984,1.463456083,0.898904864,DB0095910028372_,0.106578075,0.051048027,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,methylprednisolone,DB00959
,61439,DB00959,10033775,105,7973,41,4961,0.012735008,1.593448626,1.098676474,2.349713267,0.043172721,DB0095910033775_,3.14254645,0.465900615,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,61454,DB00153,10003658,71,7352,45,3394,0.108067073,0.728373734,0.493245278,1.08547646,0.223164003,DB0015310003658_,1.499848337,-0.316940992,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ergocalciferol,DB00153
,61456,DB01050,10003658,64,18044,79,9292,2.97298830264414e-07,0.417196397,0.294969294,0.588131149,4.85372655496903e-06,DB0105010003658_,12.23576379,-0.874198193,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ibuprofen,DB01050
,61459,DB00264,10006784,116,29491,67,24825,0.014103268,1.457400914,1.069175438,2.000315056,0.046871209,DB0026410006784_,3.060351682,0.376654654,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,61460,DB00736,10006784,51,10540,20,5533,0.316799512,1.338620553,0.78321906,2.372976107,0.484611254,DB0073610006784_,0.724408248,0.291639645,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,61462,DB01050,10006784,100,18008,24,9347,0.000398933,2.162642436,1.373038283,3.534520962,0.002557236,DB0105010006784_,5.968828217,0.771330824,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,61464,DB01373,10006784,107,22613,11,7370,3.69433187152407e-05,3.170325083,1.701233016,6.544387061,0.000340542,DB0137310006784_,7.984972484,1.153834132,female,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,calcium,DB01373
,61465,DB00153,10017885,66,7357,18,3421,0.045182112,1.704922355,0.998315365,3.056684616,0.11593243,DB0015310017885_,2.154747759,0.53351957,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,61468,DB00264,10021114,76,29531,21,24871,1.07568216065552e-06,3.047777399,1.859119856,5.205718004,1.52586646480466e-05,DB0026410021114_,11.09036304,1.114412603,female,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,metoprolol,DB00264
,61475,DB00451,10042604,44,47227,14,15405,1,1.025179,0.551231024,2.026146715,1,DB0045110042604_,0,0.024867231,NA,10042604,Supraventricular tachycardia,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,61483,DB00264,10060933,111,29496,71,24821,0.073810777,1.315582248,0.967495207,1.798773811,0.16788859,DB0026410060933_,1.784454675,0.274279342,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,61484,DB00736,10060933,45,10546,16,5537,0.223822866,1.476622384,0.817859731,2.801419619,0.378295117,DB0073610060933_,0.972080654,0.389757307,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,61487,DB01050,10060933,56,18052,15,9356,0.023378399,1.934871983,1.078647692,3.685724748,0.069747945,DB0105010060933_,2.662867316,0.660041166,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,61489,DB01373,10060933,75,22645,26,7355,0.816723442,0.936906723,0.592142931,1.526516778,0.90190424,DB0137310060933_,0.103246929,-0.06517155,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,61490,DB00153,10068319,70,7353,17,3422,0.014717486,1.916204411,1.113712254,3.478988596,0.048571678,DB0015310068319_,3.024714672,0.65034636,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,61494,DB01373,10068319,191,22529,19,7362,1.11141558946973e-08,3.285011015,2.044728575,5.580785125,2.47887643353515e-07,DB0137310068319_,15.21029024,1.189370005,female,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,61496,DB00264,10074903,129,29478,92,24800,0.250036731,1.179652291,0.895331536,1.559491347,0.409688037,DB0026410074903_,0.892359295,0.165219726,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,61497,DB00736,10074903,79,10512,23,5530,0.011777399,1.806860284,1.122091745,3.017037337,0.040569941,DB0073610074903_,3.204727865,0.591590689,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,esomeprazole,DB00736
,61500,DB01050,10074903,160,17948,88,9283,0.638264834,0.940396371,0.719622708,1.235655378,0.775482627,DB0105010074903_,0.254269699,-0.061453821,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,61504,DB00177,10047899,67,4733,31,2819,0.292951076,1.28723493,0.826758268,2.044614263,0.458523775,DB0017710047899_,0.779743134,0.252496453,NA,10047899,Weight increased,10022891,Investigations,Inv,valsartan,DB00177
,61505,DB00331,10047899,379,24567,207,20545,7.69057691923778e-07,1.531150304,1.287801807,1.824601884,1.13597535443757e-05,DB0033110047899_,11.38543384,0.426019286,NA,10047899,Weight increased,10022891,Investigations,Inv,metformin,DB00331
,61508,DB14126,10013710,30,941,54,1222,0.178195752,0.72155785,0.441998626,1.158332124,0.321566398,DB1412610013710_,1.13455123,-0.326342724,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,tenofovir,DB14126
,61509,DB00207,10011906,173,8907,193,5262,2.6655261122037e-09,0.529560615,0.4275583,0.655534832,6.80557104024033e-08,DB0020710011906_,16.5029392,-0.635707644,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,61510,DB00874,10011906,89,3246,143,1833,1.85104968846121e-14,0.351526273,0.264983622,0.464260127,1.04859571252592e-12,DB0087410011906_,27.58356926,-1.045470826,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,61513,DB00207,10043554,40,9040,29,5426,0.455963344,0.827910418,0.49993148,1.386424275,0.623389239,DB0020710043554_,0.472584173,-0.188850321,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,azithromycin,DB00207
,61515,DB00641,10043554,65,14059,92,12383,0.003765009,0.622313422,0.445427912,0.86512045,0.01624479,DB0064110043554_,4.119983054,-0.474311419,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,simvastatin,DB00641
,61516,DB00706,10043554,7,1068,122,15803,0.855576511,0.848999948,0.333419811,1.80920882,0.930193725,DB0070610043554_,0.072362408,-0.163696154,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,tamsulosin,DB00706
,61521,DB01377,10043554,47,3749,41,2629,0.327454896,0.80391015,0.515837259,1.257289515,0.495875094,DB0137710043554_,0.701431211,-0.21826777,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,magnesium oxide,DB01377
,61536,DB00381,10034674,21,29339,38,22849,0.001547845,0.430389691,0.239883684,0.752435691,0.007892357,DB0038110034674_,4.841860421,-0.843064223,NA,10034674,Peritonitis,10021881,Infections and infestations,Infec,amlodipine,DB00381
,61544,DB01222,10013710,51,9223,53,5352,0.004043637,0.558440514,0.372044508,0.837471532,0.017236193,DB0122210013710_,4.060743843,-0.582607176,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,61556,DB01222,10000060,60,9214,31,5374,0.663058343,1.128868294,0.719046953,1.804503337,0.794569675,DB0122210000060_,0.2299546,0.121215621,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,61567,DB01222,10033371,308,8966,104,5301,4.48629296537826e-07,1.750897324,1.393691552,2.214380463,7.03383302087489e-06,DB0122210033371_,11.86477876,0.560128413,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,61585,DB00091,10025482,139,5371,32,2638,4.86206177774662e-05,2.133289199,1.439382112,3.248651079,0.000431609,DB0009110025482_,7.747991498,0.757665013,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,61588,DB00635,10038153,82,32971,62,23732,0.799922066,0.952000062,0.675864118,1.346711671,0.891818188,DB0063510038153_,0.114492992,-0.049190179,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,prednisone,DB00635
,61591,DB00635,10040984,101,32952,52,23742,0.049136545,1.399428355,0.991486874,1.995816683,0.123357601,DB0063510040984_,2.092667817,0.336063836,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,61593,DB00091,10047942,44,5466,13,2657,0.12055393,1.645156595,0.868461629,3.335201047,0.242167372,DB0009110047942_,1.418126173,0.497835574,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,cyclosporine,DB00091
,61597,DB00091,10064355,72,5438,24,2646,0.1250523,1.45966494,0.906050202,2.42895761,0.248704249,DB0009110064355_,1.391490845,0.378206916,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclosporine,DB00091
,61601,DB00559,10039117,35,9624,16,3290,0.335902902,0.747823009,0.40253337,1.449026812,0.505016746,DB0055910039117_,0.68316369,-0.290588949,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,bosentan,DB00559
,61603,DB00338,10022687,87,33587,55,22217,0.863784492,1.046338952,0.737717187,1.495179069,0.937256719,DB0033810022687_,0.064798055,0.045297359,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,61604,DB00480,10022687,101,67327,141,67521,0.011972511,0.718380758,0.550704774,0.9343399,0.041077857,DB0048010022687_,3.192286071,-0.330755547,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,61605,DB01076,10022687,36,25711,32,25551,0.716214773,1.117996212,0.674778157,1.859923528,0.832149303,DB0107610022687_,0.183743403,0.111537986,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,61606,DB01234,10022687,48,31577,56,32832,0.623800838,0.891211184,0.593024891,1.334788263,0.763766695,DB0123410022687_,0.26949291,-0.115173861,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,61623,DB00588,10003239,455,16069,152,8316,2.0910457251679e-06,1.549124384,1.283904576,1.877520012,2.75804201607578e-05,DB0058810003239_,10.49840445,0.437689858,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,61624,DB00727,10003239,105,3738,84,4089,0.038882295,1.367314156,1.012798203,1.850587589,0.103391111,DB0072710003239_,2.269236289,0.312848345,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,nitroglycerin,DB00727
,61625,DB01098,10003239,245,7904,145,7064,9.04174085940325e-05,1.510041441,1.221482684,1.872175905,0.000732421,DB0109810003239_,7.219155182,0.412137095,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,61626,DB01592,10003239,186,6090,55,3012,0.000641893,1.672499945,1.22759368,2.310151716,0.003812057,DB0159210003239_,5.569586323,0.51431948,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,iron,DB01592
,61630,DB00264,10005725,51,29556,55,24837,0.205678444,0.779229274,0.521541606,1.16237979,0.356049651,DB0026410005725_,1.032685089,-0.249449958,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,metoprolol,DB00264
,61655,DB00973,10024910,41,3810,27,2994,0.539901625,1.193261658,0.714710806,2.022233433,0.695552748,DB0097310024910_,0.363048429,0.176690447,NA,10024910,Low density lipoprotein increased,10022891,Investigations,Inv,ezetimibe,DB00973
,61659,DB00727,10028334,75,3768,49,4124,0.004952369,1.675101516,1.149887155,2.459508517,0.020318899,DB0072710028334_,3.896203845,0.51587377,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,nitroglycerin,DB00727
,61660,DB01592,10028334,114,6162,54,3013,0.933948405,1.032256162,0.738062418,1.459094222,0.974527454,DB0159210028334_,0.025802588,0.031746855,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,iron,DB01592
,61665,DB00381,10031161,84,29276,29,22858,8.4947388575748e-05,2.261490668,1.466394175,3.57995064,0.0006944,DB0038110031161_,7.272462883,0.816024183,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,61672,DB00321,10033425,168,7279,58,2792,0.547643034,1.111014793,0.816843717,1.529582652,0.702288001,DB0032110033425_,0.353411701,0.105273825,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,amitriptyline,DB00321
,61673,DB00973,10033425,137,3714,54,2967,7.84532684206889e-06,2.026533119,1.462852809,2.841701304,8.78629808452411e-05,DB0097310033425_,9.339731993,0.70632651,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ezetimibe,DB00973
,61676,DB00727,10048959,86,3757,57,4116,0.003939469,1.652824081,1.165335048,2.35943928,0.01686465,DB0072710048959_,4.082535582,0.502485389,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,61677,DB00973,10048959,90,3761,38,2983,0.001131838,1.878307678,1.267849598,2.830552344,0.006100135,DB0097310048959_,5.099444355,0.6303712,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,61683,DB14512,10012735,151,4693,72,2340,0.828563549,1.045702202,0.780960687,1.410929819,0.909895047,DB1451210012735_,0.09442602,0.044688624,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,mometasone furoate,DB14512
,61685,DB01224,10013710,218,7890,154,5763,0.790285842,1.033970077,0.834902347,1.282968993,0.886410114,DB0122410013710_,0.120575553,0.033405837,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,61687,DB00581,10070863,39,2074,18,2051,0.007293243,2.142255547,1.192067456,3.992794693,0.027648791,DB0058110070863_,3.588173276,0.761859268,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,lactulose,DB00581
,61689,DB00656,10000081,181,11832,65,6554,0.002496321,1.54242464,1.153707301,2.084203802,0.011646395,DB0065610000081_,4.452758602,0.43335562,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,61690,DB00950,10000081,66,4652,17,2039,0.054203066,1.701539976,0.983761035,3.102087677,0.132847926,DB0095010000081_,2.018550216,0.531533709,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,fexofenadine,DB00950
,61691,DB01098,10000081,103,8046,92,7117,1,0.990298635,0.738863102,1.328952136,1,DB0109810000081_,0,-0.00974873,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,61693,DB00316,10008796,66,65408,41,36912,0.616309685,0.908443996,0.605958095,1.376367207,0.757494018,DB0031610008796_,0.277739638,-0.096022038,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,61698,DB00656,10030095,53,11960,29,6590,1,1.007005805,0.628058555,1.644359823,1,DB0065610030095_,0,0.006981378,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,61701,DB11089,10030095,76,10099,54,8353,0.426637703,1.164073075,0.809479797,1.684022954,0.595358464,DB1108910030095_,0.518591595,0.151925127,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,61702,DB00028,10033371,393,13065,122,5493,0.003783825,1.354391235,1.099800704,1.677497105,0.016309912,DB0002810033371_,4.115982231,0.30335208,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,61714,DB06605,10020751,101,13972,51,12982,0.000319237,1.840021389,1.300248125,2.63215271,0.002122459,DB0660510020751_,6.155179983,0.609777196,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,apixaban,DB06605
,61718,DB00065,10022086,70,9394,14,4943,0.000468301,2.63078296,1.466462291,5.062865813,0.002923866,DB0006510022086_,5.834848614,0.967281505,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,61719,DB00065,10023232,80,9384,23,4934,0.009116264,1.828760525,1.136446431,3.051541315,0.033067136,DB0006510023232_,3.409215363,0.603638428,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,infliximab,DB00065
,61720,DB00704,10022081,591,3765,312,4882,2.70571241136557e-36,2.455991034,2.12313866,2.844901136,9.00248743452455e-34,DB0070410022081_,76.09039224,0.898530359,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,61722,DB06605,10002034,284,13789,312,12721,0.038137011,0.839761248,0.711208271,0.991235521,0.101867928,DB0660510002034_,2.284078132,-0.174637657,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,apixaban,DB06605
,61723,DB06605,10018830,47,14026,45,12988,0.916921713,0.967141673,0.628332531,1.490284362,0.963011437,DB0660510018830_,0.037689991,-0.033410287,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,61724,DB06605,10027141,44,14029,68,12965,0.007852259,0.598000434,0.399355595,0.88733303,0.029338538,DB0660510027141_,3.528853332,-0.5141638,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,61729,DB00868,10028813,180,2804,64,1582,0.001554763,1.58664699,1.178073709,2.159493703,0.007919181,DB0086810028813_,4.838467488,0.461622978,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,benzonatate,DB00868
,61736,DB00005,10020100,151,127931,28,42391,0.003225425,1.78688022,1.187888269,2.77935887,0.014350086,DB0000510020100_,4.243999347,0.580471205,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,61738,DB00005,10061599,135,127947,38,42381,0.42841446,1.176764686,0.815573388,1.734487251,0.596966315,DB0000510061599_,0.515894591,0.162768881,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,61747,DB00341,10015090,74,11331,27,5041,0.449054068,1.219283893,0.77411395,1.973729229,0.616686843,DB0034110015090_,0.483393932,0.198263714,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,61759,DB00341,10022004,72,11333,23,5045,0.181699945,1.39356313,0.859878952,2.338546526,0.32606131,DB0034110022004_,1.120669847,0.33186387,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,61775,DB00341,10037844,382,11023,154,4914,0.317808426,1.105793691,0.911856948,1.346272546,0.485728259,DB0034110037844_,0.722105949,0.100563349,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cetirizine,DB00341
,61792,DB00341,10061428,179,11226,96,4972,0.146992275,0.825854247,0.639401414,1.072065947,0.279764814,DB0034110061428_,1.27380598,-0.191336978,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,cetirizine,DB00341
,61814,DB01611,10037660,228,11685,47,2314,0.805765104,0.960661774,0.696726636,1.349005408,0.894899878,DB0161110037660_,0.111043435,-0.040132884,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,61815,DB11093,10037660,36,1621,14,646,1,1.024768524,0.535097832,2.07121447,1,DB1109310037660_,0,0.024466757,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,calcium citrate,DB11093
,61828,DB08907,10033645,77,4176,91,3819,0.101941804,0.77384498,0.561886043,1.063512152,0.213867055,DB0890710033645_,1.542400697,-0.25638371,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,canagliflozin,DB08907
,61831,DB00178,10013573,48,1389,49,1631,0.535232417,1.150208667,0.751016512,1.760780914,0.691772831,DB0017810013573_,0.368497656,0.139943375,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ramipril,DB00178
,61833,DB00343,10028735,105,8631,30,5065,0.000308171,2.053835236,1.355327471,3.197995838,0.002062714,DB0034310028735_,6.183732835,0.719708892,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,61834,DB00390,10028735,70,4075,19,3282,7.58916908519308e-06,2.966768275,1.762029571,5.229216779,8.52302112387524e-05,DB0039010028735_,9.370154595,1.087473237,female,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,61835,DB00480,10028735,131,67297,108,67554,0.13658634,1.217591358,0.936332332,1.586137148,0.264937786,DB0048010028735_,1.328260251,0.19687461,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,61836,DB01234,10028735,88,31537,59,32829,0.010222472,1.552608915,1.103457334,2.198158175,0.036193115,DB0123410028735_,3.318886371,0.439936687,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,61838,DB13961,10028735,84,9373,22,6392,2.37673699969406e-05,2.60368645,1.610563911,4.37838602,0.000231337,DB1396110028735_,8.371635433,0.956928306,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,61840,DB00343,10044565,90,8646,44,5051,0.368594625,1.194980995,0.822820324,1.758040895,0.538285042,DB0034310044565_,0.619367041,0.178130282,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,61841,DB00480,10044565,503,66925,333,67329,2.65458459873881e-09,1.519615588,1.319912242,1.751310348,6.78092868589403e-08,DB0048010044565_,16.50656668,0.4184574,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,61855,DB00333,10048010,31,3040,38,3114,0.470514988,0.83567257,0.501383742,1.383204091,0.636777183,DB0033310048010_,0.451335476,-0.179518405,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,methadone,DB00333
,61858,DB00959,10007559,45,8033,29,4973,0.904701108,0.960660029,0.588393259,1.591108607,0.957638072,DB0095910007559_,0.043285367,-0.040134701,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,methylprednisolone,DB00959
,61859,DB01015,10007559,43,9844,45,9336,0.67001756,0.90624906,0.581945511,1.409594021,0.799758272,DB0101510007559_,0.223445757,-0.09844111,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,sulfamethoxazole,DB01015
,61869,DB00258,10012735,48,630,27,716,0.004197774,2.019450352,1.218475468,3.409001165,0.017759292,DB0025810012735_,4.0308464,0.702825371,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,calcium acetate,DB00258
,61875,DB01306,10033645,27,4181,32,3834,0.360956257,0.773751068,0.445078022,1.335880458,0.530871488,DB0130610033645_,0.633235307,-0.256505075,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,insulin aspart,DB01306
,61878,DB00215,10033645,37,11066,17,5259,1,1.034315782,0.567445462,1.960821114,1,DB0021510033645_,0,0.033740128,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,61880,DB00678,10033645,61,15538,42,10682,1,0.998476868,0.662531325,1.51754049,1,DB0067810033645_,0,-0.001524293,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,61882,DB00215,10047340,42,11061,14,5262,0.315707138,1.427160536,0.763208495,2.832051878,0.483348116,DB0021510047340_,0.727018148,0.355686831,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,citalopram,DB00215
,61883,DB00404,10047340,106,19786,20,9842,1.59755600301559e-05,2.636264396,1.623028053,4.492614689,0.000163615,DB0040410047340_,8.71799517,0.969362914,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,alprazolam,DB00404
,61885,DB00678,10047340,54,15545,20,10704,0.017429105,1.859123034,1.094100457,3.280923587,0.055466316,DB0067810047340_,2.89197936,0.620104889,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,losartan,DB00678
,61890,DB00203,10008469,336,13542,91,8847,2.73739556286023e-15,2.412091418,1.904932335,3.080254218,1.74008324957149e-13,DB0020310008469_,29.37967325,0.880494179,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,61893,DB06655,10018484,41,3647,36,2083,0.073154054,0.650561293,0.404128946,1.051259168,0.166776904,DB0665510018484_,1.791098262,-0.429919761,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,liraglutide,DB06655
,61896,DB00047,10020751,100,9185,48,8470,0.000180652,1.921082128,1.346802205,2.773450663,0.001323604,DB0004710020751_,6.627396669,0.652888636,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,insulin glargine,DB00047
,61897,DB00619,10003549,56,2843,37,2457,0.248413566,1.307954289,0.845059393,2.045670854,0.407778335,DB0061910003549_,0.897031549,0.268464305,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,61902,DB00619,10047895,27,2872,36,2458,0.097920498,0.641947227,0.373643492,1.090777199,0.207749102,DB0061910047895_,1.571424169,-0.44324918,NA,10047895,Weight decreased,10022891,Investigations,Inv,imatinib,DB00619
,61903,DB00625,10013710,23,553,36,1100,0.40109645,1.270627699,0.711350698,2.228422294,0.570915993,DB0062510013710_,0.560513202,0.23951103,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,efavirenz,DB00625
,61905,DB01264,10013710,15,375,78,673,8.63800076012855e-05,0.345400154,0.181852608,0.615848937,0.000704031,DB0126410013710_,7.258688818,-1.063051669,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,darunavir,DB01264
,61906,DB06817,10013710,15,667,47,695,0.000128881,0.332764343,0.171087049,0.612731628,0.000990105,DB0681710013710_,6.917699153,-1.100320719,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,raltegravir,DB06817
,61907,DB00531,10003658,66,7186,69,6447,0.387460341,0.858164955,0.601893129,1.222658499,0.557529702,DB0053110003658_,0.584239499,-0.152958943,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,cyclophosphamide,DB00531
,61909,DB00904,10003658,216,22853,240,14216,8.49357012652627e-10,0.559886902,0.463114636,0.676546069,2.39413931126802e-08,DB0090410003658_,17.54765695,-0.580020476,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ondansetron,DB00904
,61910,DB01098,10003658,70,8079,96,7113,0.004851569,0.642005676,0.464109316,0.884333312,0.01998018,DB0109810003658_,3.913014488,-0.443158134,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,rosuvastatin,DB01098
,61911,DB01306,10003658,38,4170,53,3813,0.056964162,0.655638827,0.419507811,1.015992978,0.137727361,DB0130610003658_,1.982479193,-0.422145211,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,insulin aspart,DB01306
,61912,DB01377,10003658,74,3722,87,2583,0.001127991,0.590348616,0.425200269,0.817767113,0.006084391,DB0137710003658_,5.102028693,-0.527042042,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,magnesium oxide,DB01377
,61914,DB01306,10011906,108,4100,188,3678,4.04498454568372e-08,0.51538698,0.401209255,0.659356576,7.9635414279249e-07,DB0130610011906_,14.04322185,-0.662837244,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,61915,DB06724,10011906,244,7685,184,3735,1.33151223696769e-05,0.644504825,0.527880549,0.787954324,0.000139632,DB0672410011906_,8.876499072,-0.439272969,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,61918,DB00404,10017853,47,19845,9,9853,0.006394101,2.592750038,1.255488891,6.020923868,0.024912019,DB0040410017853_,3.692404883,0.952719103,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,61922,DB00761,10017853,46,15261,19,8606,0.300933827,1.365265638,0.783726396,2.469051747,0.467261818,DB0076110017853_,0.760865539,0.311349016,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,61924,DB00904,10017853,69,23000,29,14427,0.077041842,1.492432465,0.953702741,2.390358432,0.173236221,DB0090410017853_,1.753099175,0.400407316,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,61927,DB01234,10017853,38,31587,23,32865,0.040583948,1.718993495,0.997922043,3.023212177,0.106813764,DB0123410017853_,2.236668483,0.541738942,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,61937,DB01377,10038435,54,3742,36,2634,0.830114348,1.05585211,0.677736078,1.662497191,0.910856007,DB0137710038435_,0.093370455,0.054348128,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,magnesium oxide,DB01377
,61938,DB06724,10038435,103,7826,73,3846,0.019147637,0.693402882,0.507455142,0.951640882,0.059724177,DB0672410038435_,2.818018363,-0.36614409,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,calcium carbonate,DB06724
,61939,DB08889,10038435,41,3124,54,3831,0.756392133,0.931079905,0.603084562,1.427915189,0.863504841,DB0888910038435_,0.146755775,-0.071410178,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,carfilzomib,DB08889
,61940,DB08910,10038435,155,16589,171,17317,0.656166754,0.94619472,0.755550982,1.184202805,0.789738313,DB0891010038435_,0.236053637,-0.055306896,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,pomalidomide,DB08910
,61941,DB11089,10038435,96,10079,98,8309,0.147129856,0.807575902,0.602097015,1.082935233,0.279953849,DB1108910038435_,1.273130516,-0.213718232,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,docusate,DB11089
,61944,DB00295,10038669,146,14517,104,9498,0.516133746,0.918494963,0.70837688,1.194441836,0.675861879,DB0029510038669_,0.391766544,-0.085018858,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,61945,DB00404,10038669,359,19533,324,9538,6.65644556344954e-15,0.541038394,0.463358825,0.631994469,4.02217635943152e-13,DB0040410038669_,28.54178307,-0.614265035,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,61952,DB00904,10038669,44,23025,18,14438,0.150437279,1.532789957,0.867340142,2.81955209,0.284545138,DB0090410038669_,1.25686338,0.427089576,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,61963,DB00736,10040047,74,10517,55,5498,0.050872319,0.703355383,0.488738728,1.017628177,0.126650776,DB0073610040047_,2.066321773,-0.351892991,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,61965,DB01234,10040047,452,31173,589,32299,0.000284976,0.795126131,0.701157826,0.901263922,0.001934806,DB0123410040047_,6.24774846,-0.229254522,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,61966,DB01306,10040047,44,4164,64,3802,0.019668546,0.627773368,0.416527576,0.938542273,0.061001503,DB0130610040047_,2.796856781,-0.465576056,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,insulin aspart,DB01306
,61967,DB08889,10040047,43,3122,60,3825,0.550297109,0.878070409,0.577598732,1.324914925,0.704614346,DB0888910040047_,0.350104653,-0.130028496,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,carfilzomib,DB08889
,61968,DB08910,10040047,174,16570,252,17236,0.000892752,0.718238066,0.587905441,0.875855322,0.005018924,DB0891010040047_,5.294539721,-0.330954196,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,61970,DB01590,10065154,102,4636,40,2827,0.018188023,1.554886255,1.065292638,2.308075486,0.057330644,DB0159010065154_,2.858919991,0.441402395,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,everolimus,DB01590
,61974,DB01590,10003239,80,4658,59,2808,0.251562661,0.81743304,0.57464272,1.168436876,0.411559739,DB0159010003239_,0.887801095,-0.201586288,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,everolimus,DB01590
,61976,DB01590,10042128,468,4270,180,2687,3.2701368922079e-08,1.636010444,1.365088606,1.967177148,6.55398766387225e-07,DB0159010042128_,14.23802198,0.492260622,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,everolimus,DB01590
,61979,DB01097,10008479,55,6210,9,1494,0.341515012,1.470135098,0.718693375,3.391310245,0.510708431,DB0109710008479_,0.671956437,0.3853543,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,61981,DB01097,10016256,285,5980,60,1443,0.365507648,1.146175185,0.859342723,1.549818034,0.535125103,DB0109710016256_,0.625254722,0.136430474,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,61982,DB01097,10033371,300,5965,59,1444,0.17102375,1.230874449,0.922340081,1.666095094,0.312250967,DB0109710033371_,1.163948032,0.207724851,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,61985,DB00635,10040844,93,32960,58,23736,0.409740223,1.154683599,0.822682525,1.632449754,0.579173558,DB0063510040844_,0.546153091,0.143826367,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,61987,DB01097,10047700,138,6127,12,1491,0.000148447,2.798290155,1.546016045,5.562266055,0.001116274,DB0109710047700_,6.797759046,1.029008572,female,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,leflunomide,DB01097
,61988,DB01097,10048959,137,6128,30,1473,0.693095124,1.097684144,0.731653973,1.695712863,0.815086812,DB0109710048959_,0.204460654,0.093202637,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,61989,DB00635,10061159,57,32996,9,23785,1.05396465722946e-06,4.565232874,2.243200657,10.49407314,1.49910503329417e-05,DB0063510061159_,11.10805718,1.518469526,female,10061159,Foot deformity,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,61995,DB00758,10033645,30,8270,26,10048,0.227114286,1.401876834,0.800631345,2.469836318,0.382317654,DB0075810033645_,0.96150346,0.337811935,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,61997,DB00472,10013710,205,10554,203,4109,7.9970125794592e-20,0.393193852,0.321126962,0.481441508,8.11588709077548e-18,DB0047210013710_,39.35270816,-0.933452528,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,61998,DB00722,10013710,172,25231,266,25766,2.27336035090322e-05,0.660336039,0.54145129,0.803577762,0.000222967,DB0072210013710_,8.408484758,-0.415006423,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,62002,DB00722,10018838,49,25354,46,25986,0.682517354,1.091751522,0.714759166,1.670181397,0.807961117,DB0072210018838_,0.213241344,0.087783307,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,lisinopril,DB00722
,62003,DB00999,10018838,44,21386,30,12209,0.469083463,0.837314472,0.514358123,1.380151914,0.635428717,DB0099910018838_,0.453455362,-0.177555565,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,62005,DB00175,10018884,103,8028,57,6049,0.06481475,1.361535488,0.974027009,1.919704298,0.152139283,DB0017510018884_,1.88295884,0.308613098,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,pravastatin,DB00175
,62006,DB00472,10018884,52,10707,27,4285,0.264090773,0.770765102,0.474612179,1.278222033,0.425997298,DB0047210018884_,0.853322274,-0.260371619,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,fluoxetine,DB00472
,62008,DB00175,10022595,27,8104,31,6075,0.111520646,0.652934847,0.374479085,1.131805037,0.228313746,DB0017510022595_,1.477034516,-0.42627793,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,pravastatin,DB00175
,62012,DB00175,10024855,57,8074,45,6061,0.841078033,0.950894497,0.630998956,1.440511096,0.918820335,DB0017510024855_,0.084664676,-0.050352162,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,62013,DB00472,10024855,81,10678,55,4257,0.003008888,0.587155348,0.41097847,0.844265278,0.013546049,DB0047210024855_,4.30166034,-0.532465847,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,62015,DB00175,10048294,28,8103,40,6066,0.009522856,0.524062252,0.310992374,0.871974069,0.034237215,DB0017510048294_,3.374442064,-0.6461448,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,pravastatin,DB00175
,62016,DB00472,10048294,47,10712,54,4258,1.80405500102227e-07,0.345998712,0.228557585,0.522172743,3.09064076686453e-06,DB0047210048294_,12.68713212,-1.061320228,male,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,62018,DB01164,10002034,41,6483,38,7898,0.256969811,1.31440773,0.823469875,2.102748801,0.417859007,DB0116410002034_,0.872611208,0.273386169,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,calcium chloride,DB01164
,62020,DB00927,10013700,124,7373,43,4973,0.000122674,1.944932647,1.36186015,2.824942133,0.000950456,DB0092710013700_,6.958568587,0.665227348,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,famotidine,DB00927
,62026,DB00588,10042682,86,16438,21,8447,0.001422164,2.104365806,1.292970873,3.573905725,0.007354958,DB0058810042682_,4.912380659,0.744014142,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,62034,DB00624,10013573,15,547,100,4296,0.550951398,1.178011832,0.630966297,2.055834632,0.705,DB0062410013573_,0.349557477,0.16382813,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,testosterone,DB00624
,62035,DB08816,10013573,27,1124,49,1853,0.720991311,0.908413976,0.542643084,1.491867143,0.83543276,DB0881610013573_,0.179805413,-0.096055084,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ticagrelor,DB08816
,62036,DB08816,10016256,37,1114,57,1845,0.746479645,1.07504663,0.686060487,1.666744745,0.855523435,DB0881610016256_,0.156041793,0.072364038,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ticagrelor,DB08816
,62037,DB00624,10016322,8,554,81,4315,0.612460069,0.76930215,0.319512228,1.60072728,0.754382048,DB0062410016322_,0.281856345,-0.262271474,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,testosterone,DB00624
,62038,DB01039,10016322,49,2924,27,3024,0.010616263,1.876676079,1.146713654,3.131598437,0.037330901,DB0103910016322_,3.287933852,0.629502169,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,62039,DB01136,10016322,145,9739,127,10988,0.043453555,1.288134902,1.006419244,1.650436365,0.112549952,DB0113610016322_,2.184358137,0.25319536,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,62041,DB00624,10028813,25,537,151,4245,0.225449013,1.308699199,0.813086682,2.029815526,0.380232743,DB0062410028813_,0.966971732,0.269033666,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,testosterone,DB00624
,62042,DB08816,10028813,60,1091,34,1868,2.16815303955556e-07,3.020369173,1.936778099,4.778419108,3.6450209558502e-06,DB0881610028813_,12.52214844,1.105379067,female,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ticagrelor,DB08816
,62044,DB01222,10011655,24,9250,33,5372,0.001373406,0.422391024,0.238586803,0.737560878,0.007149925,DB0122210011655_,4.940653349,-0.861823796,NA,10011655,Cushingoid,10014698,Endocrine disorders,Endo,budesonide,DB01222
,62056,DB00642,10011906,66,468,72,461,0.58542219,0.903042688,0.620586297,1.312370706,0.732945403,DB0064210011906_,0.310684064,-0.101985453,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pemetrexed,DB00642
,62057,DB00091,10010305,33,5477,20,2650,0.46289641,0.798382886,0.443741357,1.471199306,0.630116374,DB0009110010305_,0.461850756,-0.22516699,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,cyclosporine,DB00091
,62062,DB01024,10071066,58,2153,18,2102,7.28253271993006e-06,3.145372129,1.819480845,5.692614973,8.21374694457677e-05,DB0102410071066_,9.407116258,1.145932207,female,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,mycophenolic acid,DB01024
,62063,DB00788,10017788,8,9348,83,4978,3.49307404918303e-29,0.051335376,0.021434515,0.106050571,7.37473505082539e-27,DB0078810017788_,60.17173753,-2.969375179,male,10017788,Gastric haemorrhage,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,62065,DB08910,10005483,29,16715,41,17447,0.232126477,0.738301317,0.442252585,1.217806901,0.388478571,DB0891010005483_,0.945517269,-0.303403249,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,pomalidomide,DB08910
,62066,DB08910,10005557,72,16672,69,17419,0.613750219,1.090213961,0.772091462,1.540473285,0.755369411,DB0891010005557_,0.280548363,0.086373971,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,pomalidomide,DB08910
,62067,DB00331,10012607,87,24859,81,20671,0.485244807,0.893127671,0.651874143,1.224801851,0.649323411,DB0033110012607_,0.431824365,-0.11302574,NA,10012607,Diabetes mellitus inadequate control,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,62070,DB00559,10017918,41,9618,13,3293,0.87697693,1.079803554,0.566377708,2.199180934,0.947522962,DB0055910017918_,0.053904108,0.07677913,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,bosentan,DB00559
,62071,DB00682,10017918,50,19409,12,16352,1.82239624626366e-05,3.510182825,1.842418178,7.24444611,0.00018399,DB0068210017918_,8.60063147,1.255668123,female,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,warfarin,DB00682
,62079,DB00588,10000060,124,16400,46,8422,0.06157527,1.384298925,0.978403701,1.988556178,0.14633208,DB0058810000060_,1.921876722,0.32519382,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,62081,DB00455,10012735,639,8762,228,4890,7.82178104591952e-09,1.564079491,1.33687666,1.83499079,1.7987359124409e-07,DB0045510012735_,15.5310115,0.447297466,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,62082,DB00455,10037377,62,9339,39,5079,0.466750289,0.864594476,0.569146356,1.327705007,0.633382486,DB0045510037377_,0.456680796,-0.145494696,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,62083,DB00588,10046735,245,16279,71,8397,1.13983462849366e-05,1.779897427,1.359572748,2.355269444,0.000121643,DB0058810046735_,9.014423961,0.576555737,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,62092,DB00404,10029331,195,19697,101,9761,0.710145446,0.956775552,0.747649118,1.230622055,0.827129206,DB0040410029331_,0.189794361,-0.044186447,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,62093,DB00557,10029331,36,5951,23,3044,0.409915714,0.800663729,0.460709946,1.417927318,0.579359298,DB0055710029331_,0.545832445,-0.222314235,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,62096,DB13961,10029331,119,9338,111,6303,0.017654201,0.723660058,0.552878122,0.947817009,0.056037381,DB1396110029331_,2.881736295,-0.32343353,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,62112,DB00008,10035664,25,1500,30,1646,0.786439557,0.914494049,0.513165461,1.616736951,0.88414144,DB0000810035664_,0.12313823,-0.089384319,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,peginterferon alfa-2a,DB00008
,62113,DB01069,10035664,225,6475,118,2277,0.000725068,0.670570684,0.531406268,0.84962679,0.0042146,DB0106910035664_,5.469200513,-0.399626162,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,promethazine,DB01069
,62135,DB00710,10064658,61,2345,6,195,0.641946868,0.845474638,0.360408299,2.424111958,0.778480896,DB0071010064658_,0.250410828,-0.167857107,NA,10064658,Osteonecrosis of jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,ibandronate,DB00710
,62141,DB00390,10010305,53,4092,52,3249,0.322542425,0.809284384,0.539865553,1.213592105,0.490868057,DB0039010010305_,0.71157991,-0.211604899,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,digoxin,DB00390
,62142,DB01240,10010305,64,5687,24,1552,0.191993099,0.727776327,0.447146873,1.221063617,0.339137705,DB0124010010305_,1.081349045,-0.317761521,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,epoprostenol,DB01240
,62148,DB00390,10028810,64,4081,23,3278,0.000690646,2.234821828,1.365068907,3.780806294,0.004046735,DB0039010028810_,5.509844958,0.804161506,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,digoxin,DB00390
,62149,DB00706,10028810,18,1057,134,15791,0.010544375,2.006688537,1.149538233,3.310057193,0.037131658,DB0070610028810_,3.293285356,0.696485869,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,tamsulosin,DB00706
,62150,DB01136,10028810,138,9746,93,11022,0.000113858,1.678088429,1.278880608,2.21012984,0.000891766,DB0113610028810_,7.022306244,0.517655306,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,carvedilol,DB01136
,62151,DB01240,10028810,333,5418,45,1531,8.95370413466934e-07,2.09102298,1.51935079,2.937150947,1.30026581867284e-05,DB0124010028810_,11.25035675,0.73765341,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,62153,DB00695,10033295,90,27959,45,20483,0.036368172,1.465204131,1.013002707,2.145911183,0.098291851,DB0069510033295_,2.319814157,0.381994571,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,62154,DB01136,10033295,70,9814,63,11052,0.222407908,1.251255928,0.876483527,1.789554056,0.376492795,DB0113610033295_,0.976856369,0.224147789,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,62158,DB00695,10067973,50,27999,46,20482,0.301020857,0.795146886,0.521807334,1.214065946,0.467300569,DB0069510067973_,0.760782612,-0.229228419,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,furosemide,DB00695
,62162,DB00695,10070863,262,27787,167,20361,0.169340838,1.149556746,0.942359574,1.405588752,0.310021746,DB0069510070863_,1.171112835,0.13937643,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,62163,DB00706,10070863,14,1061,105,15820,0.02177098,1.987966011,1.047051961,3.501168606,0.066094965,DB0070610070863_,2.716662701,0.687112011,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,tamsulosin,DB00706
,62165,DB00660,10013700,205,1052,37,330,0.002677979,1.73747361,1.190247013,2.592926573,0.012323296,DB0066010013700_,4.39626381,0.55243211,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,metaxalone,DB00660
,62167,DB08882,10047700,39,958,20,973,0.016672562,1.979860204,1.117606407,3.610782381,0.05356454,DB0888210047700_,2.926867993,0.683026238,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,linagliptin,DB08882
,62171,DB00559,10036653,77,9582,25,3281,0.90931885,1.054607607,0.662750662,1.731920045,0.959242524,DB0055910036653_,0.041611343,0.053168761,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,bosentan,DB00559
,62172,DB00559,10049414,49,9610,19,3287,0.675603733,0.882124732,0.509079108,1.589046181,0.803379592,DB0055910049414_,0.21892796,-0.125421814,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,62220,DB00620,10003658,33,4795,37,3095,0.026273927,0.575745121,0.348110464,0.948500982,0.076369586,DB0062010003658_,2.572170747,-0.552090215,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,triamcinolone,DB00620
,62221,DB00706,10003658,13,1062,284,15641,0.185819795,0.674154393,0.35334536,1.176856566,0.331226998,DB0070610003658_,1.104951345,-0.394296124,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,tamsulosin,DB00706
,62222,DB00413,10002034,51,2148,13,1194,0.011610651,2.180268875,1.162900058,4.388315693,0.040111187,DB0041310002034_,3.216100003,0.779448206,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,pramipexole,DB00413
,62223,DB00448,10002034,79,5066,50,3074,0.854873005,0.958758486,0.662350398,1.399111193,0.929630334,DB0044810002034_,0.072968262,-0.042116075,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,lansoprazole,DB00448
,62225,DB14512,10002034,36,4808,26,2386,0.174990189,0.687141817,0.402492785,1.188265827,0.317444847,DB1451210002034_,1.147451186,-0.375214579,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,mometasone furoate,DB14512
,62238,DB00563,10048439,168,46478,15,15333,1.34869384793105e-08,3.694908626,2.176309944,6.751652519,2.94438685987272e-07,DB0056310048439_,15.03819505,1.306955825,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,62242,DB01270,10011906,398,860,403,566,1.47423415891785e-06,0.650121359,0.543825914,0.776933527,2.02721657688494e-05,DB0127010011906_,10.80626176,-0.430596227,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ranibizumab,DB01270
,62244,DB01216,10010774,6,230,177,6938,0.832747985,1.022551614,0.366391097,2.305146406,0.912909484,DB0121610010774_,0.091118545,0.022301086,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,finasteride,DB01216
,62246,DB01216,10016322,6,230,140,6975,0.474312888,1.299635429,0.464034836,2.944729017,0.639993737,DB0121610016322_,0.446296889,0.262083786,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,finasteride,DB01216
,62255,DB00331,10019641,40,24906,33,20719,1,1.008349115,0.61979544,1.650757915,1,DB0033110019641_,0,0.008314454,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,metformin,DB00331
,62257,DB00112,10021036,88,5845,40,4051,0.029559112,1.524693263,1.035403932,2.279931219,0.083746834,DB0011210021036_,2.479956911,0.421793251,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,bevacizumab,DB00112
,62260,DB00112,10021097,50,5883,61,4030,0.002565751,0.561544442,0.377594896,0.831672179,0.011905864,DB0011210021097_,4.430724203,-0.577064359,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,bevacizumab,DB00112
,62262,DB00112,10021143,42,5891,41,4050,0.117032061,0.704296418,0.446049546,1.112732141,0.236665036,DB0011210021143_,1.441109487,-0.350555963,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bevacizumab,DB00112
,62263,DB00338,10021143,172,33502,143,22129,0.04346567,0.794492873,0.632297613,0.999504579,0.112566782,DB0033810021143_,2.184208614,-0.230051263,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,62270,DB00331,10061818,161,24785,172,20580,0.023448387,0.777246484,0.622470402,0.970075566,0.06992352,DB0033110061818_,2.660353209,-0.251997754,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,62271,DB00181,10018100,38,9818,27,5844,0.52109676,0.837752541,0.497646832,1.428379947,0.680057015,DB0018110018100_,0.385578639,-0.17703252,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,62275,DB00297,10045555,38,1634,15,864,0.383210907,1.339389496,0.714985512,2.636607598,0.553292979,DB0029710045555_,0.591867619,0.29221391,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,bupivacaine,DB00297
,62281,DB00455,10003658,93,9308,58,5060,0.44106511,0.871677766,0.620084945,1.23406743,0.609232844,DB0045510003658_,0.495554746,-0.137335458,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,loratadine,DB00455
,62282,DB00512,10003658,57,4680,61,5037,1,1.005705902,0.68680835,1.470775496,1,DB0051210003658_,0,0.005689685,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,vancomycin,DB00512
,62283,DB00916,10003658,32,5291,35,2396,0.000471908,0.414078495,0.247528928,0.690473809,0.002943545,DB0091610003658_,5.82814061,-0.881699722,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,metronidazole,DB00916
,62286,DB00169,10024384,97,38594,37,18138,0.308173214,1.232052521,0.835270125,1.852270776,0.475413501,DB0016910024384_,0.743570326,0.208681495,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,62291,DB00512,10024384,38,4699,29,5069,0.177687194,1.413463303,0.847427389,2.380474706,0.32091991,DB0051210024384_,1.136563689,0.346042936,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,vancomycin,DB00512
,62295,DB00999,10024384,33,21397,19,12220,1,0.991923159,0.547486972,1.847108299,1,DB0099910024384_,0,-0.008109636,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,hydrochlorothiazide,DB00999
,62297,DB01373,10024384,40,22680,15,7366,0.638631359,0.866104872,0.467758649,1.68881162,0.775784512,DB0137310024384_,0.253880488,-0.143749279,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,calcium,DB01373
,62299,DB11089,10024384,40,10135,25,8382,0.318234046,1.323234651,0.782576301,2.277738122,0.486211457,DB1108910024384_,0.721111654,0.280079232,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,docusate,DB11089
,62300,DB00343,10040047,118,8618,59,5036,0.347554041,1.168736219,0.846221728,1.629015815,0.517077003,DB0034310040047_,0.659563473,0.15592301,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,diltiazem,DB00343
,62302,DB00455,10040047,96,9305,77,5041,0.01284923,0.675421888,0.494197159,0.925734163,0.043475835,DB0045510040047_,3.135550024,-0.392417764,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,loratadine,DB00455
,62303,DB00537,10040047,87,7470,106,4192,1.34502441773159e-07,0.460614362,0.341935835,0.619093076,2.37993718075226e-06,DB0053710040047_,12.94843647,-0.775194112,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,62304,DB00916,10040047,63,5260,78,2353,3.55827247620889e-09,0.361364506,0.254139926,0.512155146,8.84436804133812e-08,DB0091610040047_,16.24089987,-1.017868119,male,10040047,Sepsis,10021881,Infections and infestations,Infec,metronidazole,DB00916
,62306,DB06769,10040047,15,652,36,1020,0.190175731,0.651994097,0.32889338,1.232495714,0.336764853,DB0676910040047_,1.088370357,-0.42771977,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,bendamustine,DB06769
,62322,DB14726,10050584,34,1983,16,2832,0.000226006,3.034108419,1.62439357,5.9034035,0.001597141,DB1472610050584_,6.439540172,1.109917615,female,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,dabigatran,DB14726
,62323,DB00316,10019660,73,65401,46,36907,0.567400556,0.895552893,0.610750692,1.325146501,0.718565872,DB0031610019660_,0.330497898,-0.110313994,NA,10019660,Hepatic encephalopathy,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,62345,DB00787,10003983,35,16965,45,17203,0.314758304,0.788696334,0.491921483,1.255204601,0.482337566,DB0078710003983_,0.729111065,-0.237373907,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,62347,DB00996,10003983,78,38875,55,22370,0.279264176,0.816083603,0.570292697,1.17476999,0.443117028,DB0099610003983_,0.813921372,-0.203238474,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,62349,DB01234,10003983,46,31579,79,32809,0.007022388,0.604965919,0.411029074,0.881355641,0.026856303,DB0123410003983_,3.617254742,-0.502583155,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,62354,DB00316,10005169,86,65388,35,36918,0.107732657,1.387296043,0.926159007,2.11865722,0.222700868,DB0031610005169_,1.501925806,0.32735656,NA,10005169,Blindness,10015919,Eye disorders,Eye,acetaminophen,DB00316
,62357,DB00480,10005169,46,67382,44,67618,0.833764405,1.049132645,0.678623556,1.623832354,0.913682907,DB0048010005169_,0.090271697,0.04796377,NA,10005169,Blindness,10015919,Eye disorders,Eye,lenalidomide,DB00480
,62362,DB01234,10005169,43,31582,37,32851,0.434167841,1.208853451,0.760513611,1.929964408,0.602698795,DB0123410005169_,0.506337717,0.189672349,NA,10005169,Blindness,10015919,Eye disorders,Eye,dexamethasone,DB01234
,62539,DB00112,10038867,39,5894,24,4067,0.701288412,1.121306741,0.656423198,1.952332909,0.82059189,DB0011210038867_,0.197729382,0.114494739,NA,10038867,Retinal haemorrhage,10015919,Eye disorders,Eye,bevacizumab,DB00112
,62558,DB01270,10038867,40,1218,30,939,1,1.02790502,0.619149972,1.723009943,1,DB0127010038867_,0,0.02752277,NA,10038867,Retinal haemorrhage,10015919,Eye disorders,Eye,ranibizumab,DB01270
,62563,DB00047,10047513,78,9207,58,8460,0.228943657,1.235700215,0.867253245,1.769388175,0.384633538,DB0004710047513_,0.955464246,0.211637785,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,insulin glargine,DB00047
,62564,DB00112,10047513,95,5838,61,4030,0.682280325,1.075071099,0.769233328,1.512141846,0.807844246,DB0011210047513_,0.213386004,0.072386798,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,bevacizumab,DB00112
,62568,DB00620,10047513,29,4799,31,3101,0.062467287,0.604547276,0.350748091,1.039169502,0.148046211,DB0062010047513_,1.91023082,-0.503275405,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,triamcinolone,DB00620
,62569,DB00695,10047513,222,27827,101,20427,5.63731182249212e-05,1.613483796,1.268755762,2.063711843,0.000489113,DB0069510047513_,7.622917295,0.47839569,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,furosemide,DB00695
,62571,DB00863,10047513,78,10595,34,5806,0.277335085,1.257185737,0.829095505,1.942843237,0.440894684,DB0086310047513_,0.818949245,0.228875681,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ranitidine,DB00863
,62572,DB01136,10047513,71,9813,58,11057,0.076649138,1.379292372,0.960132246,1.988430853,0.172641182,DB0113610047513_,1.756539933,0.321570594,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,carvedilol,DB01136
,62574,DB01270,10047513,99,1159,77,892,1,0.989526051,0.717507429,1.368675352,1,DB0127010047513_,0,-0.010529187,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ranibizumab,DB01270
,62575,DB01306,10047513,35,4173,32,3834,1,1.004897099,0.602929941,1.680222112,1,DB0130610047513_,0,0.004885147,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,insulin aspart,DB01306
,62577,DB00112,10047531,84,5849,53,4038,0.661961003,1.094189113,0.764779785,1.57751401,0.793904753,DB0011210047531_,0.230791783,0.090013553,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,bevacizumab,DB00112
,62579,DB00230,10047531,41,19633,17,8634,0.887623194,1.060618526,0.58905213,1.99228811,0.953401944,DB0023010047531_,0.047718698,0.058852253,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,pregabalin,DB00230
,62582,DB00316,10047531,72,65402,29,36924,0.146318021,1.401686192,0.899030113,2.238351322,0.278800402,DB0031610047531_,1.277259159,0.337675935,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,acetaminophen,DB00316
,62644,DB00182,10003988,78,5116,37,2815,0.49304436,1.159957855,0.772450982,1.769905375,0.655851033,DB0018210003988_,0.4218216,0.148383673,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,amphetamine,DB00182
,62645,DB01254,10003988,28,3439,30,3118,0.597851542,0.846237839,0.485959975,1.469414363,0.742880742,DB0125410003988_,0.297219756,-0.166954826,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,dasatinib,DB01254
,62647,DB00433,10019211,237,7419,96,5924,9.44803420229702e-09,1.9711531,1.544607225,2.531906961,2.13719086925454e-07,DB0043310019211_,15.35860336,0.678618701,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,62648,DB00182,10037087,54,5140,29,2823,1,1.022686718,0.638055954,1.669922113,1,DB0018210037087_,0,0.022433202,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,amphetamine,DB00182
,62649,DB00182,10047700,142,5052,47,2805,0.002010921,1.677390307,1.194052952,2.393278779,0.009771154,DB0018210047700_,4.628320743,0.517239197,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,amphetamine,DB00182
,62658,DB01175,10003481,52,10672,19,4873,0.444018405,1.249639691,0.725571164,2.240869609,0.612009637,DB0117510003481_,0.49100725,0.222855263,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,escitalopram,DB01175
,62672,DB01175,10019063,61,10663,83,4809,8.11011502430537e-11,0.331483138,0.233763527,0.467833627,2.6831261600235e-09,DB0117510019063_,19.73628324,-1.104178335,male,10019063,Hallucination,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,62678,DB01175,10025482,300,10424,90,4802,0.000315142,1.535520083,1.206178538,1.970634374,0.002101586,DB0117510025482_,6.165062879,0.42886914,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,62679,DB01216,10025482,11,225,151,6964,0.019723897,2.254436146,1.086153993,4.228010302,0.06112629,DB0121610025482_,2.794813234,0.812899896,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,finasteride,DB01216
,62689,DB01175,10046306,67,10657,26,4866,0.575098664,1.176602979,0.736906458,1.931075961,0.724646567,DB0117510046306_,0.322071237,0.162631456,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,escitalopram,DB01175
,62694,DB00215,10057668,31,11072,19,5257,0.367778639,0.774716943,0.423568692,1.452841677,0.537462071,DB0021510057668_,0.620897087,-0.255257551,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,62699,DB01175,10061284,42,10682,13,4879,0.246050052,1.475631293,0.776187591,2.998977645,0.404986106,DB0117510061284_,0.903902517,0.389085893,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,62703,DB00215,10061623,55,11048,33,5243,0.303670859,0.790978906,0.503938724,1.258998406,0.470225393,DB0021510061623_,0.754543139,-0.234483979,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,62704,DB01175,10061623,44,10680,24,4868,0.512669041,0.835669009,0.496513534,1.438539757,0.672851533,DB0117510061623_,0.396230578,-0.179522667,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,62706,DB00215,10064355,40,11063,23,5253,0.499745402,0.825810862,0.482000269,1.446504152,0.661494141,DB0021510064355_,0.413254153,-0.191389512,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,62707,DB01175,10064355,59,10665,21,4871,0.397530489,1.283129862,0.767191584,2.225957895,0.567253272,DB0117510064355_,0.566949387,0.249302298,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,62710,DB00215,10001760,130,10973,14,5262,2.44226020966987e-10,4.45310834,2.557193439,8.38002341,7.50816486680381e-09,DB0021510001760_,18.70727476,1.493602356,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,citalopram,DB00215
,62711,DB00404,10001760,242,19650,22,9840,1.20548290606339e-21,5.508689565,3.552588296,8.958505099,1.49111144404124e-19,DB0040410001760_,43.34959499,1.706326766,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,62713,DB13961,10001760,168,9289,24,6390,2.12551241861224e-17,4.814995948,3.123660664,7.733932293,1.71904904379147e-15,DB1396110001760_,33.99700514,1.571735204,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,fish oil,DB13961
,62715,DB00215,10006784,46,11057,10,5266,0.021436859,2.190703883,1.089386084,4.872988904,0.065306888,DB0021510006784_,2.72865776,0.7842229,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,62716,DB01068,10006784,63,13700,24,6816,0.30494166,1.306011858,0.803661717,2.187806012,0.471757248,DB0106810006784_,0.751290731,0.266978111,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,62717,DB06637,10006784,57,6105,11,2008,0.119875789,1.704186547,0.882395948,3.611620343,0.241201447,DB0663710006784_,1.422122813,0.533087898,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,62719,DB13961,10006784,72,9385,24,6390,0.001698656,2.042528066,1.26962988,3.394609864,0.008499747,DB1396110006784_,4.767718857,0.714188288,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,62721,DB01068,10007882,49,13714,20,6820,0.522874604,1.218352148,0.710308005,2.165786199,0.681286752,DB0106810007882_,0.383771986,0.197499247,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,clonazepam,DB01068
,62724,DB00121,10012735,286,3937,33,435,0.77232605,0.957582856,0.656150677,1.437381515,0.875383895,DB0012110012735_,0.133092752,-0.043343028,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,biotin,DB00121
,62725,DB06637,10012735,137,6025,43,1976,0.861417975,1.044944164,0.733805101,1.514166817,0.935178278,DB0663710012735_,0.067018097,0.043963452,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dalfampridine,DB06637
,62726,DB00121,10015150,47,4176,6,462,0.647634906,0.866651242,0.367036308,2.494147432,0.78282977,DB0012110015150_,0.244840014,-0.143118642,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,biotin,DB00121
,62727,DB01068,10015150,87,13676,28,6812,0.046778438,1.547633912,0.999589895,2.464170798,0.119034925,DB0106810015150_,2.128338344,0.436727256,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,clonazepam,DB01068
,62730,DB13961,10015150,115,9342,54,6360,0.027088625,1.449810517,1.038716043,2.045499905,0.078218666,DB1396110015150_,2.548246965,0.37143287,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,fish oil,DB13961
,62731,DB06637,10019211,248,5914,56,1963,0.009858074,1.469837836,1.090549035,2.010536361,0.035163451,DB0663710019211_,3.347748051,0.385152079,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,62732,DB08880,10019211,239,3099,46,763,0.141781883,1.279134041,0.919513976,1.812329885,0.272243173,DB0888010019211_,1.301059593,0.246183319,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,teriflunomide,DB08880
,62733,DB00115,10022000,236,18189,128,10344,0.701045269,1.048533783,0.840803805,1.312453979,0.820435213,DB0011510022000_,0.197920332,0.047392791,NA,10022000,Influenza,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,62734,DB00169,10022000,479,38212,198,17977,0.135532698,1.13810976,0.961471413,1.351288764,0.263487072,DB0016910022000_,1.333750973,0.129368781,NA,10022000,Influenza,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,62735,DB00215,10022000,100,11003,27,5249,0.007449774,1.766803182,1.143630676,2.81602953,0.028142759,DB0021510022000_,3.570465194,0.569171802,NA,10022000,Influenza,10021881,Infections and infestations,Infec,citalopram,DB00215
,62736,DB00404,10022000,196,19696,63,9799,0.002241325,1.547794537,1.158416887,2.092240666,0.010670755,DB0040410022000_,4.540248488,0.436831038,NA,10022000,Influenza,10021881,Infections and infestations,Infec,alprazolam,DB00404
,62737,DB00996,10022000,402,38551,188,22237,0.01811148,1.233448043,1.03388644,1.475733867,0.05712266,DB0099610022000_,2.862554394,0.209813534,NA,10022000,Influenza,10021881,Infections and infestations,Infec,gabapentin,DB00996
,62738,DB01068,10022000,112,13651,39,6801,0.056357906,1.430719935,0.98439552,2.118807144,0.136749221,DB0106810022000_,1.989606532,0.358177769,NA,10022000,Influenza,10021881,Infections and infestations,Infec,clonazepam,DB01068
,62739,DB06637,10022000,44,6118,15,2004,0.880023431,0.960838961,0.523167761,1.862971475,0.94964348,DB0663710022000_,0.051668649,-0.039948458,NA,10022000,Influenza,10021881,Infections and infestations,Infec,dalfampridine,DB06637
,62741,DB00996,10028411,339,38614,166,22259,0.086242737,1.177235744,0.974139856,1.42714373,0.188764847,DB0099610028411_,1.667253233,0.163169101,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,62744,DB00121,10030124,51,4172,6,462,0.824033002,0.941269695,0.400933846,2.698852918,0.906757125,DB0012110030124_,0.097880643,-0.060525576,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,62745,DB00215,10030124,94,11009,32,5244,0.104424588,1.399234464,0.926485253,2.163422761,0.217634022,DB0021510030124_,1.524940425,0.335925276,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,62746,DB01068,10030124,107,13656,36,6804,0.040643203,1.48086116,1.005262431,2.22748209,0.106937597,DB0106810030124_,2.235509821,0.392623783,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,62750,DB00215,10033775,105,10998,27,5249,0.003570089,1.85598239,1.204565956,2.951755777,0.015572483,DB0021510033775_,4.162249829,0.618414146,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,62751,DB00404,10033775,251,19641,63,9799,3.42418021938063e-07,1.987661234,1.50083242,2.666407356,5.5048670988636e-06,DB0040410033775_,12.10987793,0.686958689,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,62752,DB01068,10033775,175,13588,57,6783,0.00493997,1.532572761,1.128808469,2.107709489,0.020279105,DB0106810033775_,3.89816422,0.426947866,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,62753,DB00121,10037087,138,4085,15,453,1,1.020216682,0.590959476,1.888925541,1,DB0012110037087_,0,0.020015038,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,biotin,DB00121
,62754,DB00215,10037087,185,10918,58,5218,0.004535134,1.524383985,1.127044131,2.088263576,0.018890042,DB0021510037087_,3.969120352,0.421590384,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,citalopram,DB00215
,62755,DB06637,10037087,90,6072,17,2002,0.032152872,1.745336127,1.02876661,3.135482748,0.089427885,DB0663710037087_,2.41432273,0.55694716,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,dalfampridine,DB06637
,62756,DB08880,10037087,78,3260,12,797,0.177271262,1.588936955,0.854707846,3.222614343,0.320351302,DB0888010037087_,1.138337067,0.463065211,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,teriflunomide,DB08880
,62757,DB00121,10037660,84,4139,17,451,0.027791933,0.538519816,0.313704905,0.976645703,0.079767521,DB0012110037660_,2.528638867,-0.618930985,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,62759,DB13961,10037660,166,9291,129,6285,0.255254957,0.87049532,0.68582111,1.106880917,0.415969283,DB1396110037660_,0.877143861,-0.138692897,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,62760,DB00121,10037844,144,4079,17,451,0.788707288,0.936556672,0.558517008,1.667856895,0.885552887,DB0012110037844_,0.121543098,-0.065545245,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,biotin,DB00121
,62765,DB00047,10021143,32,9253,42,8476,0.130698407,0.697944278,0.426029709,1.133463058,0.256760508,DB0004710021143_,1.359611506,-0.35961601,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,62767,DB00758,10021143,42,8258,58,10016,0.546845092,0.878313244,0.57534012,1.330776243,0.701521425,DB0075810021143_,0.354503838,-0.129751979,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,62768,DB01069,10021143,38,6662,24,2371,0.030204724,0.563556833,0.3286399,0.984336207,0.085144638,DB0106910021143_,2.463403849,-0.573487093,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,promethazine,DB01069
,62770,DB09153,10021143,75,7724,87,5612,0.003831598,0.626386147,0.452818072,0.864747098,0.016475309,DB0915310021143_,4.105892452,-0.467788249,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,62773,DB00047,10024855,70,9215,77,8441,0.281812494,0.832743452,0.592894021,1.167960764,0.445788307,DB0004710024855_,0.807911087,-0.183029665,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,62775,DB00635,10024855,135,32918,82,23712,0.241358813,1.185897858,0.894234699,1.580907059,0.399472544,DB0063510024855_,0.917610242,0.170500174,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,62776,DB00758,10024855,56,8244,74,10000,0.659045707,0.917927153,0.636048182,1.318403266,0.791749239,DB0075810024855_,0.233510554,-0.085637245,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,62777,DB01069,10024855,65,6635,16,2379,0.205349252,1.456521472,0.831140957,2.702799084,0.355573458,DB0106910024855_,1.034023419,0.376051039,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,62779,DB09153,10024855,44,7755,32,5667,1,1.004786956,0.622021272,1.639351837,1,DB0915310024855_,0,0.004775535,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,62793,DB00635,10045555,39,33014,56,23738,0.000825625,0.500750597,0.323825632,0.76745358,0.00469985,DB0063510045555_,5.360224754,-0.691647113,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,62809,DB00451,10005832,74,47197,29,15390,0.422644655,0.832045632,0.534670991,1.326772296,0.591592234,DB0045110005832_,0.524937676,-0.183867993,NA,10005832,Blood thyroid stimulating hormone decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,62829,DB01373,10018838,48,22672,11,7370,0.363608161,1.41845082,0.725928868,3.030638143,0.533175672,DB0137310018838_,0.628904318,0.349565304,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,calcium,DB01373
,62832,DB00230,10018884,75,19599,50,8601,0.024954936,0.658283883,0.453766357,0.962186656,0.07337142,DB0023010018884_,2.612220787,-0.418119007,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,pregabalin,DB00230
,62845,DB00316,10024670,79,65395,59,36894,0.110352219,0.755438293,0.532234816,1.07735876,0.226574604,DB0031610024670_,1.484681012,-0.280457177,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,62852,DB00451,10024690,82,47189,28,15391,0.824965108,0.955169928,0.614957094,1.524632223,0.907364962,DB0045110024690_,0.097210526,-0.04586602,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,levothyroxine,DB00451
,62877,DB00169,10027940,64,38627,23,18152,0.301378459,1.307576737,0.800458503,2.207809789,0.46764856,DB0016910027940_,0.760038205,0.268175605,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,62878,DB00230,10027940,53,19621,23,8628,1,1.013302184,0.609920031,1.733546998,1,DB0023010027940_,0,0.013214487,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,62879,DB00451,10027940,74,47197,21,15398,0.634600644,1.149636738,0.69991347,1.966372028,0.772834708,DB0045110027940_,0.257690084,0.139446012,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,62885,DB00230,10028372,216,19458,88,8563,0.573477623,1.080182574,0.838094361,1.402182325,0.723331142,DB0023010028372_,0.323888151,0.077130076,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,62886,DB00927,10028372,71,7426,41,4975,0.498248648,1.160095162,0.777586363,1.751183836,0.660253873,DB0092710028372_,0.415130861,0.148502038,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,famotidine,DB00927
,62897,DB00472,10030124,57,10702,23,4289,1,0.993203606,0.601366512,1.691370246,1,DB0047210030124_,0,-0.006819595,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,62898,DB00874,10030124,48,3287,34,1942,0.42240424,0.834124817,0.524429127,1.339899186,0.591447087,DB0087410030124_,0.525183055,-0.181372227,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,62899,DB00927,10030124,115,7382,54,4962,0.032654975,1.431444592,1.02510314,2.020589318,0.090536998,DB0092710030124_,2.401996693,0.358684138,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,62901,DB00472,10033425,187,10572,47,4265,0.003446858,1.605090077,1.157702397,2.264432582,0.015135428,DB0047210033425_,4.190717087,0.473179878,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,fluoxetine,DB00472
,62905,DB00927,10038153,43,7454,18,4998,0.115302522,1.601720898,0.903329565,2.954166582,0.234105268,DB0092710038153_,1.451984401,0.471078612,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,famotidine,DB00927
,62906,DB01373,10038153,96,22624,37,7344,0.36472166,0.842210631,0.570256317,1.267522274,0.534352466,DB0137310038153_,0.626699609,-0.17172514,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,calcium,DB01373
,62908,DB13961,10038153,41,9416,27,6387,1,1.030031982,0.617847628,1.743203574,1,DB1396110038153_,0,0.029589853,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,fish oil,DB13961
,62909,DB00230,10040984,142,19532,48,8603,0.132875168,1.302966806,0.932237149,1.849170852,0.259783691,DB0023010040984_,1.347905953,0.264643823,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,62910,DB00316,10040984,179,65295,98,36855,0.851007429,1.030964919,0.801158277,1.333204055,0.926529161,DB0031610040984_,0.076309759,0.030495179,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,62912,DB01373,10040984,87,22633,23,7358,0.437304225,1.229713837,0.768719512,2.042596703,0.605725057,DB0137310040984_,0.501329097,0.206781489,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,calcium,DB01373
,62913,DB13961,10040984,43,9414,19,6395,0.121618836,1.537338788,0.875969624,2.796042616,0.243731662,DB1396110040984_,1.411687407,0.430052862,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,fish oil,DB13961
,62924,DB00230,10047942,92,19582,35,8616,0.500224111,1.156547624,0.775118894,1.760878935,0.661803989,DB0023010047942_,0.412785856,0.145439381,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,pregabalin,DB00230
,62925,DB00874,10047942,35,3300,26,1950,0.42432689,0.79550199,0.463754787,1.380641684,0.593157248,DB0087410047942_,0.522295741,-0.22878193,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,guaifenesin,DB00874
,62926,DB00927,10047942,128,7369,63,4953,0.044661114,1.365584194,1,1.881156467,0.114909689,DB0092710047942_,2.16360877,0.311582318,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,famotidine,DB00927
,62928,DB00874,10053762,58,3277,37,1939,0.748412065,0.927543476,0.601178154,1.447048827,0.857130893,DB0087410053762_,0.154164638,-0.075215611,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,guaifenesin,DB00874
,62929,DB05259,10053762,55,11215,14,2714,0.878843493,0.950700913,0.520647111,1.854202425,0.949052042,DB0525910053762_,0.052291643,-0.050555763,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,glatiramer,DB05259
,62930,DB13961,10053762,245,9212,146,6268,0.230074323,1.141747499,0.923980735,1.414905041,0.386039615,DB1396110053762_,0.951815285,0.132559982,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,fish oil,DB13961
,62934,DB01373,10059570,36,22684,15,7366,0.416785537,0.779340415,0.415887765,1.533049697,0.585981002,DB0137310059570_,0.534467909,-0.249307339,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,calcium,DB01373
,62937,DB00472,10061818,53,10706,16,4296,0.352453275,1.32915128,0.74725369,2.493816995,0.522178752,DB0047210061818_,0.649745314,0.284540603,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,62938,DB00874,10061818,32,3303,24,1952,0.405425108,0.788020035,0.448312848,1.402519171,0.575068748,DB0087410061818_,0.553265684,-0.238231764,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,62939,DB01373,10061818,182,22538,71,7310,0.187093751,0.831391849,0.62778593,1.111268022,0.33287706,DB0137310061818_,1.099982046,-0.184654056,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,62940,DB05259,10061818,48,11222,17,2711,0.207237565,0.682127117,0.384541675,1.267318173,0.357923609,DB0525910061818_,1.027435699,-0.38253925,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,62945,DB06626,10042128,21,667,33,1419,0.302451578,1.353666116,0.738175565,2.431427814,0.468827608,DB0662610042128_,0.757520151,0.302816553,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,axitinib,DB06626
,62947,DB00497,10070863,1426,17841,1190,15185,0.639297372,1.019926575,0.940837634,1.105795235,0.776360343,DB0049710070863_,0.253138508,0.019730639,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,62948,DB00683,10070863,83,1501,50,1588,0.001885814,1.755897472,1.212321012,2.565249765,0.0092751,DB0068310070863_,4.680421888,0.562980106,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,midazolam,DB00683
,62949,DB00761,10070863,117,15190,64,8561,0.876780145,1.030321189,0.752396623,1.421857813,0.947388231,DB0076110070863_,0.054046311,0.029870588,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,62950,DB00818,10070863,61,1359,48,1629,0.031702885,1.523089635,1.018874152,2.288238713,0.088442614,DB0081810070863_,2.425401364,0.420740927,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,propofol,DB00818
,62966,DB00620,10053762,167,4661,103,3029,0.704117374,1.053657231,0.815632303,1.366341236,0.822565564,DB0062010053762_,0.195327087,0.052267189,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,triamcinolone,DB00620
,62968,DB09153,10053762,148,7651,92,5607,0.235396589,1.178898225,0.900527568,1.550128699,0.392501862,DB0915310053762_,0.935213998,0.164580295,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium chloride,DB09153
,62969,DB00207,10000081,136,8944,60,5395,0.045026296,1.367219675,0.999883365,1.888498253,0.115611624,DB0020710000081_,2.157518777,0.312779243,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,62971,DB00213,10024690,36,18859,29,13392,0.616542075,0.881523554,0.525265342,1.491265809,0.757634803,DB0021310024690_,0.277553799,-0.126103557,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,pantoprazole,DB00213
,62972,DB00264,10024690,52,29555,32,24860,0.188340755,1.366848325,0.863203536,2.194993869,0.33445053,DB0026410024690_,1.095266304,0.312507597,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,metoprolol,DB00264
,62975,DB08895,10024690,84,28030,30,6616,0.056058935,0.660901707,0.430487009,1.039924898,0.136196423,DB0889510024690_,1.99365715,-0.414150154,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,tofacitinib,DB08895
,62987,DB01409,10013952,76,5955,24,3942,0.001327644,2.096073073,1.306940189,3.475592221,0.006955774,DB0140910013952_,4.968183161,0.740065629,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,62989,DB01409,10039101,44,5987,15,3951,0.031793349,1.935671659,1.054960203,3.749770931,0.088638967,DB0140910039101_,2.423183705,0.660454377,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,62998,DB00563,10020937,339,46307,96,15252,0.200120033,1.163071823,0.923918818,1.475686823,0.349167654,DB0056310020937_,1.052203088,0.151064628,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,62999,DB00005,10023204,112,127970,29,42390,0.283340898,1.279296373,0.843914103,1.997099143,0.447689177,DB0000510023204_,0.803656088,0.246310218,NA,10023204,Joint dislocation,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,63000,DB00563,10023204,52,46594,8,15340,0.050141853,2.139818657,1.009211241,5.217567149,0.125301003,DB0056310023204_,2.077036416,0.760721086,NA,10023204,Joint dislocation,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,63005,DB00563,10049848,103,46543,22,15326,0.077031607,1.541609431,0.965427087,2.56753632,0.173220617,DB0056310049848_,1.753189255,0.432826956,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,63006,DB00736,10010305,81,10510,52,5501,0.271415828,0.815330843,0.567570967,1.180183491,0.43422898,DB0073610010305_,0.83418328,-0.204161306,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,esomeprazole,DB00736
,63007,DB00169,10016322,688,38003,228,17947,2.75237959885243e-06,1.425038944,1.223694142,1.664432313,3.51025219581932e-05,DB0016910016322_,10.25723758,0.354199142,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,63008,DB00736,10016322,149,10442,58,5495,0.055428115,1.35186975,0.989911958,1.867428935,0.135042344,DB0073610016322_,2.002166887,0.301488635,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,63009,DB00736,10022061,52,10539,13,5540,0.012931351,2.102580972,1.127778703,4.212987662,0.043694635,DB0073610022061_,3.130529951,0.743165624,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,63010,DB01104,10022061,77,15386,10,7276,1.40323660555736e-05,3.640882625,1.875427388,7.898517267,0.000146394,DB0110410022061_,8.82920607,1.292226132,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,63011,DB00736,10022437,189,10402,105,5448,0.620825516,0.94274593,0.736986355,1.211269257,0.761279125,DB0073610022437_,0.272755201,-0.05895846,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,esomeprazole,DB00736
,63012,DB00736,10027175,100,10491,44,5509,0.378260631,1.193410189,0.827836547,1.745104016,0.548283925,DB0073610027175_,0.600962015,0.176814914,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,63013,DB00736,10044565,87,10504,60,5493,0.116041857,0.758306328,0.538587587,1.073685194,0.235233888,DB0073610044565_,1.447174992,-0.276667849,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,63027,DB00005,10057371,54,128028,6,42413,0.006527214,2.981615617,1.284128609,8.48186723,0.025325532,DB0000510057371_,3.675942241,1.092465307,female,10057371,Hypoaesthesia oral,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,63030,DB01076,10045555,65,25682,81,25502,0.1850586,0.796850095,0.565637935,1.118749952,0.330228466,DB0107610045555_,1.107970542,-0.227088705,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,63036,DB00641,10003481,30,14094,28,12447,0.895471367,0.946198569,0.545979742,1.644663287,0.95615204,DB0064110003481_,0.044838341,-0.055302828,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,simvastatin,DB00641
,63037,DB00813,10003481,51,10521,56,10112,0.499201141,0.875316916,0.586404752,1.304001217,0.661049497,DB0081310003481_,0.41392656,-0.133169269,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,fentanyl,DB00813
,63048,DB00186,10005557,90,16811,50,9958,0.792652266,1.066234559,0.745713723,1.539691522,0.88758728,DB0018610005557_,0.119248419,0.064133338,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,lorazepam,DB00186
,63051,DB01306,10005557,264,3944,205,3661,0.063399516,1.195371279,0.986587812,1.449935957,0.149638108,DB0130610005557_,1.899535514,0.17845683,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,insulin aspart,DB01306
,63053,DB01306,10010305,33,4175,41,3825,0.200395916,0.737435022,0.450749208,1.198149231,0.349482926,DB0130610010305_,1.051300571,-0.304577301,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,insulin aspart,DB01306
,63055,DB00186,10018838,35,16866,27,9981,0.296191078,0.767148703,0.450841788,1.318613906,0.462042968,DB0018610018838_,0.772097387,-0.265074621,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,lorazepam,DB00186
,63057,DB00497,10018838,37,19230,46,16329,0.097700057,0.683019507,0.430534513,1.076893751,0.207442122,DB0049710018838_,1.57290291,-0.381231859,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,oxycodone,DB00497
,63058,DB00641,10018838,32,14092,23,12452,0.500105578,1.229376264,0.696834412,2.201454397,0.661728287,DB0064110018838_,0.41290025,0.206506938,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,simvastatin,DB00641
,63061,DB11089,10018838,52,10123,25,8382,0.028693394,1.722219436,1.048569849,2.899033601,0.081818168,DB1108910018838_,2.503255963,0.543613829,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,docusate,DB11089
,63063,DB00813,10018884,76,10496,51,10117,0.049940592,1.436356053,0.99312535,2.092474334,0.124893054,DB0081310018884_,2.080297473,0.362109387,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,fentanyl,DB00813
,63064,DB01306,10018884,43,4165,43,3823,0.745137729,0.91790481,0.585845464,1.438159264,0.854485157,DB0130610018884_,0.157256147,-0.085661587,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,insulin aspart,DB01306
,63065,DB11089,10018884,164,10011,112,8295,0.12765324,1.213277014,0.946588542,1.559691095,0.252328127,DB1108910018884_,1.377024948,0.193324975,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,docusate,DB11089
,63066,DB00215,10024264,70,11033,42,5234,0.225298261,0.79069475,0.530983027,1.190122484,0.380158826,DB0021510024264_,0.967166151,-0.23484329,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,63068,DB00641,10024264,56,14068,55,12420,0.633926558,0.898910788,0.60791382,1.329685405,0.77235374,DB0064110024264_,0.258312622,-0.106571484,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,63069,DB00813,10024264,52,10520,77,10091,0.016851551,0.647803132,0.44619384,0.93398549,0.054030618,DB0081310024264_,2.918204395,-0.434168438,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,63071,DB11089,10024264,71,10104,50,8357,0.410363982,1.174468799,0.805430729,1.723981332,0.579751524,DB1108910024264_,0.545155674,0.160815959,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,docusate,DB11089
,63091,DB00186,10038153,82,16819,47,9961,0.927312181,1.033282342,0.712685637,1.513474716,0.969361391,DB0018610038153_,0.031117784,0.032740476,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,lorazepam,DB00186
,63093,DB00497,10038153,62,19205,60,16315,0.524329733,0.877839918,0.605122975,1.274265993,0.682463396,DB0049710038153_,0.382046386,-0.130291027,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,oxycodone,DB00497
,63094,DB00813,10038153,31,10541,21,10147,0.266406622,1.420984467,0.790223705,2.603702819,0.428552069,DB0081310038153_,0.847343033,0.351349918,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,fentanyl,DB00813
,63096,DB11089,10038153,60,10115,43,8364,0.48900038,1.153787918,0.766111058,1.750682477,0.652422465,DB1108910038153_,0.427062975,0.143050372,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,docusate,DB11089
,63098,DB00186,10038669,96,16805,64,9944,0.461365822,0.887599953,0.639563655,1.23886597,0.628664915,DB0018610038669_,0.46415689,-0.11923414,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,63099,DB00215,10038669,92,11011,50,5226,0.470649452,0.873308998,0.611292135,1.260338266,0.636922979,DB0021510038669_,0.451106543,-0.135465836,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,63101,DB00497,10038669,306,18961,216,16159,0.037516312,1.207308628,1.009666048,1.445653001,0.10060882,DB0049710038669_,2.296515349,0.188393608,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,63103,DB00813,10038669,205,10367,284,9884,5.41903006911163e-05,0.688217509,0.570975617,0.828345698,0.000472749,DB0081310038669_,7.656946445,-0.373650345,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,63105,DB00186,10040752,39,16862,25,9983,0.796065979,0.92358821,0.544602899,1.593366197,0.889537655,DB0018610040752_,0.11705344,-0.079488967,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,lorazepam,DB00186
,63109,DB00813,10040752,15,10557,51,10117,3.11802826708896e-06,0.281848073,0.147088826,0.509678343,3.91803910801625e-05,DB0081310040752_,10.14733416,-1.266387103,male,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,fentanyl,DB00813
,63114,DB00813,10045555,81,10491,133,10035,0.000112542,0.582570354,0.435763018,0.774789565,0.000882906,DB0081310045555_,7.032291315,-0.540305322,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,63147,DB00497,10059570,37,19230,28,16347,0.709213737,1.123293757,0.66874385,1.906585156,0.826468108,DB0049710059570_,0.19059395,0.116265224,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,oxycodone,DB00497
,63152,DB00476,10033645,49,17208,17,6160,1,1.03182133,0.583350276,1.912553877,1,DB0047610033645_,0,0.031325522,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,63156,DB01156,10033645,43,13579,19,6309,1,1.051492906,0.599212554,1.912190794,1,DB0115610033645_,0,0.05021097,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,63158,DB00028,10037087,502,12956,258,5357,0.006463987,0.804554562,0.688564174,0.941751213,0.025126576,DB0002810037087_,3.683829202,-0.217466494,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,human immunoglobulin g,DB00028
,63161,DB00448,10008531,56,5089,20,3104,0.04290338,1.70773671,1.006622242,3.010785796,0.111500491,DB0044810008531_,2.19372628,0.535168932,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,63163,DB00065,10011224,107,9357,51,4906,0.613965369,1.100018688,0.77944035,1.570112127,0.755564886,DB0006510011224_,0.280289617,0.095327169,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,infliximab,DB00065
,63164,DB01097,10011224,116,6149,28,1475,1,0.993774346,0.65019569,1.566403034,1,DB0109710011224_,0,-0.006245115,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,leflunomide,DB01097
,63165,DB00448,10013709,211,4934,113,3011,0.292801683,1.139516614,0.898218384,1.451649503,0.458399132,DB0044810013709_,0.780015006,0.13060415,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,63166,DB01097,10013709,1601,4664,343,1160,0.028643319,1.160908333,1.014630943,1.330372252,0.081698186,DB0109710013709_,2.50472348,0.149202744,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,63167,DB00448,10013946,39,5106,23,3101,1,1.029809453,0.59862932,1.809743219,1,DB0044810013946_,0,0.029373788,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,lansoprazole,DB00448
,63168,DB00635,10013946,184,32869,88,23706,0.001338232,1.508007234,1.162794108,1.968178958,0.006997997,DB0063510013946_,4.96213125,0.410789067,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,63169,DB00959,10013946,54,8024,14,4988,0.002454371,2.39758848,1.311720851,4.678679275,0.011498642,DB0095910013946_,4.46552631,0.874463432,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,63177,DB00316,10051792,457,65017,339,36614,0.000154235,0.759187655,0.65780457,0.876814608,0.001154839,DB0031610051792_,6.763793924,-0.275506293,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,63179,DB00635,10051792,169,32884,98,23696,0.093170371,1.242651093,0.96264799,1.611464532,0.200374997,DB0063510051792_,1.607564685,0.217247076,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,63183,DB00563,10021688,74,46572,9,15339,0.002099176,2.708167387,1.351581212,6.155916661,0.01012419,DB0056310021688_,4.592827657,0.996272165,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,methotrexate,DB00563
,63187,DB00121,10028334,90,4133,8,460,0.732250651,1.252028673,0.603695523,3.007923295,0.844418874,DB0012110028334_,0.169106611,0.224765174,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,biotin,DB00121
,63188,DB00158,10028334,235,16580,90,8014,0.064612606,1.262037661,0.98424735,1.630152163,0.151779739,DB0015810028334_,1.885324894,0.232727606,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,63196,DB01068,10051055,69,13694,26,6814,0.274619902,1.320548365,0.82928307,2.162536348,0.437902458,DB0106810051055_,0.825759092,0.278047078,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,clonazepam,DB01068
,63197,DB01592,10051055,33,6243,23,3044,0.199819916,0.699588915,0.397812661,1.250197092,0.348802397,DB0159210051055_,1.053249716,-0.357262381,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,iron,DB01592
,63210,DB00338,10000269,33,33641,20,22252,0.888511783,1.091415004,0.607804653,2.007744561,0.953826126,DB0033810000269_,0.047273882,0.087475023,NA,10000269,Abscess,10021881,Infections and infestations,Infec,omeprazole,DB00338
,63216,DB00338,10022095,162,33512,47,22225,1.24175136114878e-07,2.28586512,1.642085469,3.235745587,2.21518896106513e-06,DB0033810022095_,13.02017285,0.826744561,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,63221,DB00973,10023232,42,3809,14,3007,0.004215404,2.368023696,1.264901325,4.703887138,0.017825271,DB0097310023232_,4.027138122,0.862055724,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,ezetimibe,DB00973
,63235,DB00563,10014020,52,46594,11,15337,0.241478811,1.555987387,0.801849465,3.308100297,0.399575683,DB0056310014020_,0.917352089,0.44211032,NA,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,methotrexate,DB00563
,63236,DB00563,10052251,61,46585,19,15329,0.897520415,1.056414199,0.622343821,1.873243363,0.956338178,DB0056310052251_,0.044643686,0.054880343,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,63237,DB01098,10001551,52,8097,45,7164,0.91920182,1.022404623,0.671809257,1.561329367,0.964295004,DB0109810001551_,0.03635801,0.022157326,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,rosuvastatin,DB01098
,63238,DB01098,10003481,51,8098,34,7175,0.230604259,1.329005004,0.843458279,2.118045057,0.386625966,DB0109810003481_,0.950297549,0.284430545,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,rosuvastatin,DB01098
,63243,DB00678,10000081,202,15397,125,10599,0.365294151,1.112446531,0.884378977,1.403765753,0.534887012,DB0067810000081_,0.625699746,0.106561672,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,63244,DB01225,10000081,136,4908,81,4559,0.001552513,1.559543415,1.172170693,2.08600842,0.007910022,DB0122510000081_,4.839624698,0.444393096,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,63246,DB08900,10000081,101,910,38,399,0.496646824,1.165286405,0.77904055,1.772788004,0.658795476,DB0890010000081_,0.417342147,0.152966898,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,teduglutide,DB08900
,63249,DB00682,10005802,34,19425,19,16345,0.16855108,1.505716962,0.834480109,2.795485025,0.308967723,DB0068210005802_,1.174518462,0.409269172,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,warfarin,DB00682
,63256,DB00316,10005911,75,65399,57,36896,0.102220768,0.742349892,0.51892998,1.066901151,0.214324006,DB0031610005911_,1.540266363,-0.297934595,NA,10005911,Body temperature increased,10022891,Investigations,Inv,acetaminophen,DB00316
,63266,DB00678,10008531,129,15470,67,10657,0.067921448,1.326339746,0.97880746,1.811333313,0.157567209,DB0067810008531_,1.847903186,0.282423078,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,63267,DB00682,10008531,172,19287,101,16263,0.004085259,1.435945003,1.115626311,1.85637287,0.017376977,DB0068210008531_,4.052609111,0.361823171,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,63268,DB00715,10008531,38,4805,15,2272,0.658219946,1.197816279,0.642103049,2.349106133,0.791206443,DB0071510008531_,0.234196355,0.180500132,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,63269,DB01225,10008531,44,5000,34,4606,0.495267467,1.192118576,0.743269661,1.926883127,0.657577764,DB0122510008531_,0.419192249,0.17573204,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,63273,DB00916,10012735,296,5027,131,2300,0.788600658,1.033803473,0.83360563,1.287487226,0.885530673,DB0091610012735_,0.121568183,0.033244693,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,metronidazole,DB00916
,63274,DB01225,10012735,254,4790,182,4458,0.009262401,1.298835574,1.064653775,1.586999681,0.033479403,DB0122510012735_,3.396824856,0.261468151,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,63276,DB08900,10012735,53,958,19,418,0.512837122,1.216936466,0.698432998,2.205247284,0.672984419,DB0890010012735_,0.396033101,0.196336607,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,teduglutide,DB08900
,63277,DB00572,10013968,136,2766,85,2041,0.265226449,1.180579746,0.888060847,1.576688791,0.427186937,DB0057210013968_,0.85053357,0.166005628,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atropine,DB00572
,63278,DB00916,10013968,138,5185,65,2366,0.818605142,0.96882539,0.713241778,1.327402775,0.90321487,DB0091610013968_,0.101794803,-0.031670879,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metronidazole,DB00916
,63279,DB01225,10013968,255,4789,166,4474,0.000388466,1.435044835,1.17046839,1.763134436,0.002504187,DB0122510013968_,5.989791188,0.361196092,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enoxaparin,DB01225
,63283,DB00316,10015137,43,65431,23,36930,0.898430784,1.055207293,0.621809065,1.834608224,0.956410053,DB0031610015137_,0.044568532,0.053737234,NA,10015137,Eructation,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,63304,DB00682,10023232,142,19317,73,16291,0.000567225,1.640463345,1.227507323,2.208144162,0.003427472,DB0068210023232_,5.675932386,0.494978729,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,63305,DB00695,10023232,295,27754,136,20392,4.90919749823508e-06,1.593721091,1.295286542,1.969031564,5.82039946960347e-05,DB0069510023232_,9.751556568,0.466071591,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,63312,DB00678,10028813,974,14625,414,10310,6.52483826912969e-18,1.658489588,1.472618856,1.87021449,5.57741053346582e-16,DB0067810028813_,35.12263688,0.505907301,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,63313,DB01225,10028813,259,4785,152,4488,5.29968337190165e-06,1.598100828,1.297408915,1.973899478,6.22301440386129e-05,DB0122510028813_,9.684671045,0.468815942,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,63326,DB00572,10033371,95,2807,51,2075,0.074158934,1.376898064,0.964787028,1.984585368,0.168476024,DB0057210033371_,1.780961832,0.31983319,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,atropine,DB00572
,63327,DB00678,10033371,568,15031,209,10515,4.15194944857761e-16,1.901127095,1.616163939,2.243083254,2.89864518607869e-14,DB0067810033371_,31.17194785,0.642446918,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,63328,DB01225,10033371,134,4910,78,4562,0.001058697,1.596105097,1.194752851,2.144649689,0.005777608,DB0122510033371_,5.153765526,0.467566347,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,63334,DB00678,10047700,428,15171,216,10508,0.000156193,1.372430832,1.160310138,1.62707423,0.001167836,DB0067810047700_,6.752602923,0.316583498,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,63336,DB08900,10047700,67,944,15,422,0.01799667,1.995922627,1.112353505,3.80779196,0.056852181,DB0890010047700_,2.867300703,0.691106413,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,teduglutide,DB08900
,63347,DB00316,10062544,51,65423,17,36936,0.058752091,1.693707283,0.961853177,3.128873479,0.141167212,DB0031610062544_,1.95781019,0.526919785,NA,10062544,Tooth fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,63360,DB00186,10063743,45,16856,31,9977,0.552814474,0.859214147,0.531481699,1.405496133,0.706536098,DB0018610063743_,0.347380985,-0.15173709,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,lorazepam,DB00186
,63390,DB00953,10053762,71,1626,12,220,0.489170932,0.800638683,0.422403272,1.648722098,0.652567206,DB0095310053762_,0.426841148,-0.222345517,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,rizatriptan,DB00953
,63424,DB06724,10013700,113,7816,28,3891,0.000584733,2.008975585,1.315857747,3.162803208,0.003519509,DB0672410013700_,5.649433654,0.697624933,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,calcium carbonate,DB06724
,63438,DB00448,10001760,76,5069,9,3115,2.56224890516551e-08,5.188249098,2.589202597,11.79729389,5.25340970922584e-07,DB0044810001760_,14.45921832,1.64639628,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,lansoprazole,DB00448
,63439,DB01050,10001760,199,17909,19,9352,2.18229878986887e-18,5.469688529,3.40828702,9.282284867,1.94776650905613e-16,DB0105010001760_,36.17467815,1.699221673,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,63440,DB00448,10002855,81,5064,35,3089,0.100882115,1.411639557,0.935966075,2.168545314,0.212126425,DB0044810002855_,1.550572836,0.344751835,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,lansoprazole,DB00448
,63464,DB00448,10012378,87,5058,29,3095,0.003756847,1.835579958,1.190238467,2.906425794,0.016214903,DB0044810012378_,4.121824525,0.607360485,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,lansoprazole,DB00448
,63473,DB01050,10019303,98,18010,30,9341,0.011335779,1.69424723,1.114523443,2.644716895,0.039334778,DB0105010019303_,3.23564622,0.52723853,NA,10019303,Heart rate increased,10022891,Investigations,Inv,ibuprofen,DB01050
,63476,DB01050,10019465,31,18077,22,9349,0.250006868,0.72872723,0.40831368,1.321793821,0.409651874,DB0105010019465_,0.892447569,-0.316455787,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,63478,DB00448,10020937,69,5076,18,3106,0.00077184,2.345396472,1.377128479,4.196187769,0.00443935,DB0044810020937_,5.417247408,0.852454459,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,lansoprazole,DB00448
,63479,DB01050,10020937,267,17841,90,9281,0.000311052,1.543255712,1.20924506,1.98488537,0.00207935,DB0105010020937_,6.175700057,0.433894284,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,63488,DB00448,10047700,175,4970,79,3045,0.025509292,1.357145044,1.030491571,1.800397017,0.074629832,DB0044810047700_,2.595214953,0.305383261,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lansoprazole,DB00448
,63502,DB00327,10005750,36,6102,28,4234,0.70259519,0.89213117,0.528476223,1.520314892,0.821576595,DB0032710005750_,0.196530108,-0.114142105,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,hydromorphone,DB00327
,63503,DB00813,10005750,55,10517,39,10129,0.148875392,1.358204164,0.884018058,2.104727024,0.282431959,DB0081310005750_,1.264317612,0.30616336,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,fentanyl,DB00813
,63505,DB00297,10013573,34,1638,25,854,0.212789672,0.709131272,0.407799587,1.2486795,0.364777002,DB0029710013573_,1.008469064,-0.343714619,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,bupivacaine,DB00297
,63506,DB00813,10013573,203,10369,124,10044,5.60471906534771e-05,1.585741394,1.259839802,2.002615489,0.000486847,DB0081310013573_,7.627559713,0.461052054,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,63510,DB00181,10019303,51,9805,41,5830,0.16035207,0.739651067,0.480013008,1.145866653,0.297964312,DB0018110019303_,1.210781559,-0.301576735,NA,10019303,Heart rate increased,10022891,Investigations,Inv,baclofen,DB00181
,63512,DB00813,10019303,57,10515,24,10144,0.000489686,2.290968148,1.397970972,3.863583133,0.003040728,DB0081310019303_,5.795658464,0.8289745,NA,10019303,Heart rate increased,10022891,Investigations,Inv,fentanyl,DB00813
,63513,DB00297,10041349,39,1633,20,859,1,1.025740814,0.579722008,1.868527356,1,DB0029710041349_,0,0.025415097,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,bupivacaine,DB00297
,63515,DB06186,10003988,39,2170,44,3602,0.087243735,1.471130588,0.927698655,2.325287476,0.190504804,DB0618610003988_,1.658077867,0.386031213,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ipilimumab,DB06186
,63520,DB01118,10011906,191,2872,258,4451,0.163935647,1.14730115,0.940848333,1.39724033,0.302697375,DB0111810011906_,1.195021735,0.137412358,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,63521,DB01118,10012735,110,2953,120,4589,0.009151322,1.424409239,1.084908091,1.868653087,0.033162266,DB0111810012735_,3.406342626,0.353757159,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,amiodarone,DB01118
,63524,DB00390,10007554,80,4065,56,3245,0.486450676,1.140360051,0.797710783,1.639829704,0.650341082,DB0039010007554_,0.430258312,0.131344047,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,digoxin,DB00390
,63527,DB09140,10007554,85,3656,43,1755,0.775151683,0.948911769,0.646975111,1.409612612,0.877413689,DB0914010007554_,0.130776688,-0.052439458,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,oxygen,DB09140
,63529,DB09140,10010264,278,3463,96,1702,0.003505673,1.423162431,1.115901129,1.827549749,0.015338596,DB0914010010264_,4.177383026,0.352881459,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,63531,DB00169,10064911,85,38606,14,18161,8.19177267558473e-05,2.856071737,1.611667897,5.447282655,0.000673088,DB0016910064911_,7.303634973,1.049447162,female,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,63532,DB00338,10064911,115,33559,42,22230,0.000767359,1.813734192,1.26306039,2.649158584,0.004417925,DB0033810064911_,5.422085239,0.595387809,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,63535,DB09140,10064911,210,3531,71,1727,0.008787134,1.446533074,1.092984906,1.933010837,0.032099974,DB0914010064911_,3.438900062,0.36916971,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,63562,DB00047,10053762,193,9092,196,8322,0.32962137,0.901306067,0.733290428,1.107759442,0.49829462,DB0004710053762_,0.696563771,-0.103910382,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,63589,DB00207,10022437,125,8955,42,5413,0.000713681,1.798939424,1.256649449,2.620877019,0.004158527,DB0020710022437_,5.482594341,0.587197283,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,azithromycin,DB00207
,63590,DB00727,10022437,67,3776,57,4116,0.175361648,1.281233341,0.883915097,1.862570348,0.317899302,DB0072710022437_,1.146020607,0.247823162,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,nitroglycerin,DB00727
,63591,DB00207,10033775,64,9016,22,5433,0.024941643,1.752940783,1.063788731,2.992720462,0.073348747,DB0020710033775_,2.612529861,0.561294825,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,63592,DB00656,10033775,144,11869,52,6567,0.008486151,1.532154797,1.106812609,2.14972068,0.031223191,DB0065610033775_,3.466594158,0.426675108,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,63593,DB00727,10033775,44,3799,32,4141,0.084477475,1.498695591,0.92693386,2.447325295,0.185839493,DB0072710033775_,1.682871917,0.404595124,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,63594,DB00924,10033775,158,10004,26,4225,1.22887529969876e-06,2.566337912,1.684558128,4.056460533,1.72042541957826e-05,DB0092410033775_,10.97035387,0.942479946,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,63595,DB06403,10038428,76,21395,30,6631,0.254098704,0.785168929,0.50782503,1.242559599,0.414693094,DB0640310038428_,0.880216565,-0.241856388,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,ambrisentan,DB06403
,63596,DB01257,10011906,32,904,26,542,0.270948901,0.738088946,0.421045346,1.304679804,0.433653527,DB0125710011906_,0.835509389,-0.303690939,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,eculizumab,DB01257
,63625,DB00153,10037377,48,7375,41,3398,0.004170944,0.539415973,0.347389061,0.841087434,0.017669959,DB0015310037377_,4.035889325,-0.617268255,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,63627,DB00788,10037377,48,9308,39,5022,0.070728128,0.664037397,0.425498938,1.042170237,0.162571715,DB0078810037377_,1.81663605,-0.40941681,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,naproxen,DB00788
,63641,DB01261,10012378,60,3721,47,3256,0.62575394,1.117028994,0.747509628,1.677951591,0.765305338,DB0126110012378_,0.26748039,0.110672477,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,sitagliptin,DB01261
,63648,DB01261,10028411,39,3742,20,3283,0.050261039,1.710678978,0.971555297,3.102443544,0.125479547,DB0126110028411_,2.075612502,0.536890355,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sitagliptin,DB01261
,63652,DB01261,10052747,23,3758,50,3253,0.00020964,0.398233875,0.231383978,0.666570529,0.001499219,DB0126110052747_,6.502810669,-0.920715819,NA,10052747,Adenocarcinoma pancreas,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sitagliptin,DB01261
,63656,DB01261,10062060,28,3753,50,3253,0.001977962,0.485446651,0.29354239,0.788229287,0.009639473,DB0126110062060_,4.641888874,-0.722685881,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,sitagliptin,DB01261
,63676,DB00526,10010774,42,1556,44,1850,0.584909631,1.134860338,0.721382745,1.783148565,0.732568728,DB0052610010774_,0.311198116,0.126509593,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,oxaliplatin,DB00526
,63679,DB00526,10016173,28,1570,31,1863,0.793845468,1.071750231,0.616495489,1.855608964,0.888291402,DB0052610016173_,0.118455435,0.069293042,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,oxaliplatin,DB00526
,63700,DB00526,10043554,58,1540,75,1819,0.657592456,0.913489153,0.632507189,1.313626095,0.79072338,DB0052610043554_,0.234807082,-0.090483778,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,oxaliplatin,DB00526
,63731,DB00678,10007554,51,15548,30,10694,0.571537729,1.169230964,0.730138304,1.902771218,0.72168084,DB0067810007554_,0.326172288,0.156346237,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,losartan,DB00678
,63734,DB00904,10007554,90,22979,70,14386,0.192605164,0.804935281,0.582019625,1.117104782,0.339933307,DB0090410007554_,1.079005838,-0.216993401,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,ondansetron,DB00904
,63735,DB00999,10007554,31,21399,39,12200,0.00108988,0.453177231,0.273243831,0.745752897,0.005912185,DB0099910007554_,5.130739873,-0.791471992,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,63738,DB14500,10007554,47,7762,36,4037,0.082640969,0.679015991,0.429807454,1.080887093,0.182785077,DB1450010007554_,1.699444256,-0.387110601,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,potassium,DB14500
,63740,DB00169,10016100,65,38626,31,18144,1,0.98492913,0.632519872,1.564055349,1,DB0016910016100_,0,-0.015185589,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,63743,DB00381,10016100,57,29303,46,22841,0.920888947,0.965858641,0.6432248,1.457433262,0.964941435,DB0038110016100_,0.035687869,-0.03473779,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,63749,DB00678,10016100,35,15564,23,10701,0.894517897,1.046272525,0.60060485,1.855767892,0.955948677,DB0067810016100_,0.045051053,0.045233872,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,63750,DB00695,10016100,71,27978,65,20463,0.193381706,0.798919104,0.5622529,1.13676413,0.340891833,DB0069510016100_,1.076190056,-0.224495585,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,63757,DB00169,10023232,430,38261,122,18053,3.20102399514533e-07,1.663022449,1.355971114,2.052082598,5.17459506226292e-06,DB0016910023232_,12.17174947,0.508636699,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,63760,DB00341,10023232,94,11311,20,5048,0.00154162,2.097488516,1.282663064,3.593649791,0.007869014,DB0034110023232_,4.844822466,0.740740684,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,63761,DB00448,10023232,40,5105,11,3113,0.019554126,2.217241241,1.11445661,4.79929224,0.060725448,DB0044810023232_,2.801392422,0.796263739,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,lansoprazole,DB00448
,63762,DB00575,10023232,41,5203,16,3813,0.031435753,1.87778706,1.029334276,3.590404274,0.087865671,DB0057510023232_,2.4319461,0.630093988,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,clonidine,DB00575
,63765,DB00836,10023232,43,5492,18,4057,0.050423826,1.764592277,0.994794743,3.255711115,0.12580164,DB0083610023232_,2.073048897,0.567919659,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,loperamide,DB00836
,63766,DB00904,10023232,139,22930,69,14387,0.116349046,1.263926212,0.939687251,1.713657766,0.235669133,DB0090410023232_,1.445326435,0.234222918,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,63770,DB00316,10027727,48,65426,26,36927,0.904243885,1.04198717,0.633527087,1.750010262,0.957497529,DB0031610027727_,0.043432138,0.04112963,NA,10027727,Mitral valve incompetence,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,63779,DB00695,10027727,49,28000,23,20505,0.093982834,1.560146431,0.932223821,2.683757943,0.20173002,DB0069510027727_,1.600825009,0.444779683,NA,10027727,Mitral valve incompetence,10007541,Cardiac disorders,Card,furosemide,DB00695
,63788,DB00575,10030124,66,5178,33,3796,0.081751686,1.466141901,0.949202676,2.30427718,0.181298719,DB0057510030124_,1.707609229,0.382634393,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,63795,DB00669,10033425,103,6274,12,1085,0.231847126,1.4842954,0.810625011,2.976395812,0.388122262,DB0066910033425_,0.946434881,0.394940182,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sumatriptan,DB00669
,63796,DB00678,10033425,400,15199,166,10558,1.6350539544099e-08,1.673822462,1.390862174,2.021705069,3.49267721996459e-07,DB0067810033425_,14.8674271,0.51510991,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,63797,DB00804,10033425,79,2921,21,878,0.718392971,1.130724923,0.686917572,1.938521808,0.833647929,DB0080410033425_,0.181944114,0.122858952,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,dicyclomine,DB00804
,63798,DB00836,10033425,127,5408,58,4017,0.002028862,1.626369643,1.179634217,2.265210403,0.009836511,DB0083610033425_,4.621654237,0.486350318,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,loperamide,DB00836
,63803,DB00341,10043607,71,11334,48,5020,0.027924703,0.65516338,0.447204192,0.967132124,0.080056805,DB0034110043607_,2.52501883,-0.422870639,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,cetirizine,DB00341
,63805,DB00482,10043607,30,8229,30,3041,0.000193217,0.369584551,0.214836279,0.635743664,0.001399286,DB0048210043607_,6.57179294,-0.995375739,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,celecoxib,DB00482
,63808,DB00836,10043607,66,5469,42,4033,0.493857593,1.158777141,0.773503695,1.753088957,0.656558632,DB0083610043607_,0.42074328,0.14736526,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,loperamide,DB00836
,63809,DB00904,10043607,200,22869,157,14299,0.037716041,0.796520711,0.642349866,0.989077459,0.10104639,DB0090410043607_,2.292175564,-0.227502148,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,ondansetron,DB00904
,63830,DB00341,10048959,215,11190,59,5009,0.000731251,1.631156794,1.215138941,2.218683443,0.004242563,DB0034110048959_,5.462587612,0.489289453,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,63831,DB00482,10048959,172,8087,51,3020,0.17061965,1.259399925,0.913688156,1.762192886,0.311689022,DB0048210048959_,1.165749312,0.230635358,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,63832,DB00572,10048959,56,2846,26,2100,0.055312705,1.589133237,0.977632719,2.646142114,0.134882127,DB0057210048959_,2.003354014,0.463188734,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,atropine,DB00572
,63833,DB00669,10048959,68,6309,10,1087,0.748855714,1.171570276,0.597377771,2.560533374,0.857491671,DB0066910048959_,0.153743813,0.158344965,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,63834,DB00678,10048959,394,15205,193,10531,7.64536403963496e-05,1.413891885,1.184995136,1.691585466,0.000633339,DB0067810048959_,7.364505087,0.346346104,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,63835,DB00804,10048959,48,2952,7,892,0.07557661,2.071591706,0.927651776,5.446328945,0.170752208,DB0080410048959_,1.76754185,0.728317252,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,dicyclomine,DB00804
,63836,DB00836,10048959,116,5419,55,4020,0.006214871,1.564523889,1.122473151,2.203503764,0.024345437,DB0083610048959_,3.715410857,0.447581553,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,63839,DB14500,10048959,235,7574,106,3967,0.224157798,1.161147182,0.916216919,1.479482266,0.378721357,DB1450010048959_,0.97095455,0.149408467,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,63849,DB00341,10028810,212,11193,60,5008,0.00144209,1.580852745,1.179272251,2.146629666,0.007444093,DB0034110028810_,4.900334403,0.457964414,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,cetirizine,DB00341
,63850,DB00635,10028810,547,32506,186,23608,8.18742950675295e-21,2.135800733,1.803553815,2.538418007,9.3976674491267e-19,DB0063510028810_,41.50865525,0.758841627,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,prednisone,DB00635
,63851,DB08895,10028810,823,27291,140,6506,0.000180184,1.401392395,1.167623913,1.692124417,0.001320543,DB0889510028810_,6.629712499,0.33746631,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,63860,DB00367,10037660,88,22712,9,458,0.000146765,0.197209743,0.098498149,0.448322572,0.001105841,DB0036710037660_,6.807149193,-1.623487431,male,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,levonorgestrel,DB00367
,63862,DB00331,10049119,40,24906,10,20742,0.000287784,3.331061044,1.636480603,7.473158102,0.001949862,DB0033110049119_,6.239996875,1.203290885,female,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,metformin,DB00331
,63866,DB00193,10069868,57,19263,8,8694,0.000668102,3.21546382,1.52567778,7.806697314,0.003942761,DB0019310069868_,5.535873959,1.167971615,female,10069868,Device issue,10077536,Product issues,Prod,tramadol,DB00193
,63867,DB00331,10069868,67,24879,29,20723,0.002788206,1.92435162,1.226959278,3.087704886,0.012731757,DB0033110069868_,4.363655891,0.65458909,NA,10069868,Device issue,10077536,Product issues,Prod,metformin,DB00331
,63875,DB08908,10025256,164,10509,61,3218,0.204730438,0.823260782,0.608273013,1.12662347,0.354735634,DB0890810025256_,1.036382461,-0.194482261,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,dimethyl fumarate,DB08908
,63878,DB00005,10040808,120,127962,68,42351,0.000678501,0.584059354,0.4301016,0.798632093,0.003991585,DB0000510040808_,5.523566841,-0.537752668,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,etanercept,DB00005
,63879,DB00005,10048865,277,127805,229,42190,2.80284448286403e-23,0.399307907,0.333851403,0.477966699,3.85721294408801e-21,DB0000510048865_,47.00434207,-0.918022464,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,etanercept,DB00005
,63894,DB00836,10051055,45,5490,46,4029,0.13528674,0.717961357,0.464274592,1.109620858,0.263086743,DB0083610051055_,1.335271482,-0.331339532,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,loperamide,DB00836
,63895,DB01069,10051055,53,6647,26,2369,0.199142625,0.726537989,0.445142234,1.213314086,0.347989889,DB0106910051055_,1.055581854,-0.319464507,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,promethazine,DB01069
,63897,DB14500,10051055,50,7759,53,4020,0.000350648,0.488800601,0.324735485,0.734833803,0.002297306,DB1450010051055_,6.076018272,-0.715800643,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,potassium,DB14500
,63898,DB00169,10056812,159,38532,48,18127,0.007022373,1.55832174,1.121391786,2.200558912,0.026856303,DB0016910056812_,3.617254742,0.443609434,NA,10056812,Body height decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,63899,DB00264,10056812,82,29525,38,24854,0.002331823,1.816481166,1.221684627,2.744647087,0.011024728,DB0026410056812_,4.507614572,0.596901204,NA,10056812,Body height decreased,10022891,Investigations,Inv,metoprolol,DB00264
,63901,DB00381,10056812,66,29294,36,22851,0.089657837,1.430093542,0.938489244,2.211103814,0.194675849,DB0038110056812_,1.636419418,0.357739856,NA,10056812,Body height decreased,10022891,Investigations,Inv,amlodipine,DB00381
,63903,DB00480,10056812,247,67181,227,67435,0.357472499,1.092199919,0.908111998,1.314122741,0.527178423,DB0048010056812_,0.640216224,0.088193937,NA,10056812,Body height decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,63904,DB00695,10056812,61,27988,33,20495,0.174816533,1.353595649,0.871913839,2.13553706,0.317217394,DB0069510056812_,1.148167955,0.302764496,NA,10056812,Body height decreased,10022891,Investigations,Inv,furosemide,DB00695
,63907,DB01076,10056812,72,25675,27,25556,6.83586940458745e-06,2.654411705,1.683473039,4.299504598,7.78007479106218e-05,DB0107610056812_,9.461359514,0.97622305,NA,10056812,Body height decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,63909,DB01234,10056812,120,31505,121,32767,0.846525061,1.031469058,0.794145059,1.339548857,0.922987088,DB0123410056812_,0.080140034,0.030984056,NA,10056812,Body height decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,63912,DB00338,10008111,40,33634,36,22236,0.19726217,0.734591849,0.456298205,1.186441427,0.345688097,DB0033810008111_,1.062218364,-0.308440241,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,63916,DB00761,10008111,31,15276,27,8598,0.101260598,0.646210467,0.372943041,1.126193133,0.212726569,DB0076110008111_,1.547747652,-0.436630028,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,63917,DB00904,10008111,26,23043,40,14416,0.000329155,0.406655972,0.2381588,0.683336061,0.002177113,DB0090410008111_,6.129755775,-0.899787729,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,63919,DB01076,10008111,64,25683,81,25502,0.157603438,0.784560788,0.555986136,1.103041628,0.294273148,DB0107610008111_,1.223246869,-0.242631223,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,63937,DB00316,10041962,31,65443,19,36934,0.770110067,0.920814673,0.503929524,1.725487541,0.874040593,DB0031610041962_,0.134628459,-0.082496487,NA,10041962,Status epilepticus,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,63961,DB00682,10007598,65,19394,37,16327,0.058875993,1.478921083,0.972446339,2.279511161,0.141355086,DB0068210007598_,1.956480211,0.391312824,NA,10007598,Cardiac pacemaker insertion,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,63962,DB00682,10042609,76,19383,46,16318,0.08365283,1.39090333,0.951423507,2.053229087,0.184510752,DB0068210042609_,1.690047542,0.329953414,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,63967,DB00273,10003549,153,8328,32,2161,0.312424899,1.240640817,0.840338939,1.883035606,0.47991634,DB0027310003549_,0.734143481,0.215628034,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,63968,DB00333,10003549,42,3029,40,3112,0.740265895,1.078731339,0.680648865,1.712070522,0.850770212,DB0033310003549_,0.161613208,0.075785665,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,methadone,DB00333
,63969,DB00668,10003549,110,9981,36,4267,0.173816925,1.30622738,0.887551145,1.963390199,0.31591487,DB0066810003549_,1.152282501,0.26714312,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,63970,DB00852,10003549,38,1128,13,458,0.753375229,1.186721532,0.611518344,2.45136543,0.86125771,DB0085210003549_,0.149361504,0.17119449,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pseudoephedrine,DB00852
,63972,DB00921,10003549,57,5788,52,4851,0.69942564,0.918708823,0.618431283,1.367384061,0.819305805,DB0092110003549_,0.199297877,-0.084786048,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,63975,DB10631,10003549,45,1251,11,200,0.236267861,0.654235447,0.326284882,1.426833455,0.393455445,DB1063110003549_,0.932787446,-0.424287982,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,cranberry,DB10631
,63976,DB11074,10003549,41,1219,27,841,0.900684486,1.047624251,0.62360297,1.785964984,0.956760749,DB1107410003549_,0.04420192,0.046524983,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,dimethicone,DB11074
,63977,DB11133,10003549,90,2341,42,1532,0.084812306,1.402216419,0.955876705,2.085884703,0.186457967,DB1113310003549_,1.679549441,0.338054141,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,63978,DB00182,10006451,47,5147,9,2843,0.001831473,2.884234091,1.394773041,6.704053365,0.009051475,DB0018210006451_,4.704827554,1.059259385,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,amphetamine,DB00182
,63979,DB00273,10006451,62,8419,12,2181,0.469564174,1.338420704,0.712735962,2.733915766,0.635899654,DB0027310006451_,0.452714505,0.291490339,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,topiramate,DB00273
,63981,DB00425,10006451,140,12555,42,7442,5.60611674048014e-05,1.975776649,1.388719871,2.863628042,0.000486888,DB0042510006451_,7.62747559,0.680961561,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,zolpidem,DB00425
,63982,DB00476,10006451,189,17068,31,6146,1.43425331691942e-05,2.195382845,1.493944565,3.326005476,0.000149263,DB0047610006451_,8.809802662,0.786356448,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,duloxetine,DB00476
,63983,DB00557,10006451,56,5931,12,3055,0.004306787,2.403557904,1.271112431,4.933987007,0.018138674,DB0055710006451_,4.009708918,0.876950099,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,hydroxyzine,DB00557
,63984,DB00668,10006451,344,9747,61,4242,2.46345038944365e-12,2.45417812,1.859672387,3.285765029,1.04098270900378e-10,DB0066810006451_,22.98568575,0.897791927,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,epinephrine,DB00668
,63985,DB00697,10006451,100,5996,10,1796,0.000220277,2.99512261,1.55831889,6.450731101,0.00156296,DB0069710006451_,6.461173841,1.096985169,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,tizanidine,DB00697
,63989,DB00956,10006451,43,5771,21,3446,0.517566344,1.222615764,0.708428855,2.172921505,0.677147475,DB0095610006451_,0.389866193,0.200992632,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,hydrocodone,DB00956
,63991,DB01050,10006451,180,17928,42,9329,7.37454794063366e-07,2.230053402,1.584647708,3.202604464,1.09328817044307e-05,DB0105010006451_,11.42373564,0.802025532,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,63992,DB01068,10006451,148,13615,31,6809,2.12149321019043e-06,2.387536998,1.610406596,3.643622798,2.79166202902906e-05,DB0106810006451_,10.48628834,0.87026229,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,clonazepam,DB01068
,63993,DB01075,10006451,406,19542,75,11022,6.25226501616008e-23,3.053106413,2.378500139,3.96480975,8.4277326128086e-21,DB0107510006451_,46.22275918,1.116159568,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,63994,DB06724,10006451,98,7831,25,3894,0.001992279,1.949140773,1.243480044,3.162624998,0.009694908,DB0672410006451_,4.636154438,0.667388646,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,63999,DB00182,10046571,53,5141,7,2845,5.75642895296539e-05,4.189366343,1.894692681,10.93522874,0.000497805,DB0018210046571_,7.60530275,1.432549492,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,amphetamine,DB00182
,64000,DB00425,10046571,259,12436,62,7422,5.15016091111438e-12,2.493045059,1.880032846,3.35002085,2.07944669045532e-10,DB0042510046571_,22.29374909,0.913504879,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,zolpidem,DB00425
,64004,DB01068,10046571,310,13453,56,6784,7.13744420917591e-15,2.791399233,2.090943493,3.786042296,4.29800048197454e-13,DB0106810046571_,28.4754563,1.026542987,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,clonazepam,DB01068
,64005,DB06724,10046571,237,7692,57,3862,1.56730272577161e-07,2.087482392,1.553069665,2.846332961,2.73005647096798e-06,DB0672410046571_,12.81118826,0.735958743,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,64007,DB10631,10046571,123,1173,20,191,1,1.001405732,0.603204476,1.738719446,1,DB1063110046571_,0,0.001404744,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,cranberry,DB10631
,64008,DB11074,10046571,49,1211,21,847,0.064377232,1.631625501,0.952152748,2.886822662,0.151342056,DB1107410046571_,1.888212731,0.489576758,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,dimethicone,DB11074
,64009,DB11133,10046571,75,2356,14,1560,1.50517728389506e-06,3.54624338,1.979041019,6.821882668,2.06544426557983e-05,DB1113310046571_,10.78758012,1.26588884,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,omega-3 fatty acids,DB11133
,64011,DB00273,10048393,107,8374,11,2182,0.001780543,2.53450612,1.357912266,5.238596097,0.008841329,DB0027310048393_,4.728318074,0.929998794,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,64015,DB00338,10048393,184,33490,34,22238,1.02399025172301e-14,3.593426566,2.48095192,5.347392519,6.01465559028813e-13,DB0033810048393_,28.13940712,1.279106223,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,64016,DB00425,10048393,114,12581,29,7455,1.72593967008261e-05,2.329284652,1.536424194,3.636961509,0.000175363,DB0042510048393_,8.648654295,0.845561204,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,64017,DB00557,10048393,44,5943,8,3059,0.004696257,2.830711768,1.315943417,6.970087619,0.019448736,DB0055710048393_,3.939973214,1.040528188,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,64023,DB00996,10048393,460,38493,118,22307,3.80289677175818e-17,2.259067996,1.840235143,2.791325776,2.97055398649818e-15,DB0099610048393_,33.45002793,0.814952337,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,64029,DB11089,10048393,64,10111,28,8379,0.004402001,1.894088216,1.195990913,3.070828201,0.018454004,DB1108910048393_,3.992473892,0.63873757,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,docusate,DB11089
,64031,DB00108,10048709,51,10143,29,3266,0.018196526,0.566296514,0.351526596,0.928246948,0.057339288,DB0010810048709_,2.858769229,-0.568637461,NA,10048709,Urosepsis,10021881,Infections and infestations,Infec,natalizumab,DB00108
,64033,DB00169,10048709,45,38646,30,18145,0.138372429,0.704266593,0.433883913,1.158260529,0.267474576,DB0016910048709_,1.318730759,-0.350598312,NA,10048709,Urosepsis,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,64043,DB00635,10048709,44,33009,18,23776,0.052445571,1.760682019,0.996460682,3.238376213,0.129597805,DB0063510048709_,2.043319436,0.565701245,NA,10048709,Urosepsis,10021881,Infections and infestations,Infec,prednisone,DB00635
,64074,DB00635,10061259,31,33022,22,23772,1,1.014381983,0.568571058,1.839229165,1,DB0063510061259_,0,0.014279543,NA,10061259,Klebsiella infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,64115,DB00254,10053762,132,5803,98,3290,0.051729789,0.76368564,0.581435378,1.005806791,0.128287338,DB0025410053762_,2.053482702,-0.26959904,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,doxycycline,DB00254
,64121,DB00563,10071066,78,46568,54,15294,4.45451911449325e-05,0.474382509,0.330880805,0.684511636,0.000400503,DB0056310071066_,7.822789447,-0.745741302,NA,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,64131,DB08895,10046306,520,27594,65,6581,1.74895270745764e-07,1.907889699,1.46977566,2.512600209,3.00957262949422e-06,DB0889510046306_,12.71371247,0.645997762,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,64135,DB00625,10028813,22,554,38,1098,0.676694562,1.147341774,0.639687229,2.012365741,0.803963008,DB0062510028813_,0.218202021,0.137447766,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,efavirenz,DB00625
,64136,DB00734,10028813,99,3951,52,4850,5.40189785123301e-07,2.336836673,1.64937805,3.344244665,8.31560087962868e-06,DB0073410028813_,11.69737718,0.848798166,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,risperidone,DB00734
,64137,DB09065,10028813,44,708,103,1834,0.571957151,1.106527246,0.750876548,1.608297008,0.722058026,DB0906510028813_,0.325649775,0.101226504,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cobicistat,DB09065
,64192,DB00051,10006451,180,25551,46,11374,0.000501099,1.741863794,1.252844857,2.465413768,0.003096234,DB0005110006451_,5.777568766,0.554955686,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,adalimumab,DB00051
,64199,DB00051,10034839,54,25677,12,11408,0.031678715,1.999266736,1.055839057,4.107336666,0.088398597,DB0005110034839_,2.425899184,0.692780481,NA,10034839,Pharyngitis streptococcal,10021881,Infections and infestations,Infec,adalimumab,DB00051
,64200,DB00051,10037855,84,25647,34,11386,0.690418251,1.096814327,0.727765283,1.686423477,0.813248655,DB0005110037855_,0.206718367,0.092409912,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,64201,DB00563,10037855,96,46550,31,15317,1,1.018980171,0.673106305,1.581691451,1,DB0056310037855_,0,0.018802295,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,64202,DB00563,10039227,66,46580,14,15334,0.153802849,1.551875846,0.862568033,2.993211112,0.289208992,DB0056310039227_,1.240605696,0.439464423,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,64209,DB00203,10008531,168,13710,68,8870,0.000987975,1.598371267,1.197450447,2.153789028,0.005449929,DB0020310008531_,5.212152667,0.468985152,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,64210,DB01240,10008531,133,5618,50,1526,0.055845162,0.722562792,0.515527893,1.026485721,0.135808217,DB0124010008531_,1.996511559,-0.324950953,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,64220,DB00005,10018388,43,128039,9,42410,0.261149332,1.582477458,0.76083512,3.692395945,0.422692213,DB0000510018388_,0.861110994,0.45899163,NA,10018388,Glossodynia,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,64222,DB00472,10016322,175,10584,51,4261,0.045099354,1.381353224,1.003782252,1.930081022,0.115765681,DB0047210016322_,2.156187124,0.323063616,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,64229,DB00425,10028391,76,12619,44,7440,1,1.018377432,0.692662253,1.513461823,1,DB0042510028391_,0,0.018210607,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,64244,DB00727,10012378,69,3774,55,4118,0.085866765,1.368835787,0.94377025,1.993538149,0.188146708,DB0072710012378_,1.67053326,0.313960588,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,nitroglycerin,DB00727
,64245,DB01136,10012378,118,9766,75,11040,8.59634459163355e-05,1.778511344,1.318599333,2.411665655,0.000701179,DB0113610012378_,7.262747421,0.575776691,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,carvedilol,DB01136
,64247,DB00153,10013709,292,7131,131,3308,0.789886338,1.034012384,0.834939834,1.2859838,0.886130966,DB0015310013709_,0.120890522,0.033446753,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,64248,DB00758,10022437,112,8188,122,9952,0.427818855,1.115803535,0.854086561,1.45666445,0.596354496,DB0075810022437_,0.516919997,0.109574805,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,clopidogrel,DB00758
,64249,DB01136,10022437,155,9729,139,10976,0.052257832,1.258016675,0.992415959,1.595982419,0.129273645,DB0113610022437_,2.045823844,0.229536414,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,carvedilol,DB01136
,64251,DB09539,10028813,38,629,25,655,0.093125272,1.582283199,0.918446278,2.769401969,0.200294393,DB0953910028813_,1.607967031,0.458868867,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,omega-3-acid ethyl esters,DB09539
,64252,DB00437,10029331,84,6837,158,11388,0.385562171,0.88551929,0.670167373,1.163196784,0.555660053,DB0043710029331_,0.587598588,-0.121581038,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,64253,DB00727,10029331,31,3812,31,4142,0.799076611,1.086544245,0.637482536,1.852021114,0.891461684,DB0072710029331_,0.114892822,0.083002243,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,64254,DB00758,10029331,63,8237,93,9981,0.258009707,0.820857018,0.58567329,1.144051381,0.418926099,DB0075810029331_,0.870060748,-0.19740634,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,64255,DB01136,10029331,93,9791,98,11017,0.662774014,1.067776192,0.794176429,1.434870047,0.794417715,DB0113610029331_,0.230145866,0.06557816,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,64256,DB06643,10029331,144,52277,61,7454,8.81873037120746e-11,0.336606122,0.247588373,0.462377282,2.89027840158589e-09,DB0664310029331_,19.66191301,-1.088841809,male,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,64258,DB14500,10029331,131,7678,69,4004,0.94024086,0.990073057,0.732177773,1.34874252,0.979559074,DB1450010029331_,0.020652733,-0.009976543,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,potassium,DB14500
,64262,DB01373,10042209,116,22604,15,7366,0.000226276,2.520135974,1.465184451,4.650033769,0.001598837,DB0137310042209_,6.438478826,0.924312858,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,calcium,DB01373
,64267,DB08910,10047895,120,16624,151,17337,0.127661227,0.828792163,0.646032798,1.061372841,0.252328127,DB0891010047895_,1.377024948,-0.187785864,NA,10047895,Weight decreased,10022891,Investigations,Inv,pomalidomide,DB08910
,64270,DB01592,10002855,110,6166,33,3034,0.011867121,1.640098038,1.099625643,2.505695716,0.040814822,DB0159210002855_,3.198709968,0.494756019,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,iron,DB01592
,64271,DB01069,10012378,164,6536,22,2373,1.28916242850061e-06,2.70605929,1.723229339,4.448305459,1.79478995938234e-05,DB0106910012378_,10.92803746,0.99549344,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,promethazine,DB01069
,64272,DB01592,10012378,127,6149,32,3035,0.000445903,1.958756405,1.316806295,2.991329871,0.002807655,DB0159210012378_,5.875405687,0.672309785,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,iron,DB01592
,64275,DB01069,10022116,51,6649,6,2389,0.005942918,3.053974534,1.308115444,8.719387905,0.023488399,DB0106910022116_,3.751248627,1.116443868,female,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,promethazine,DB01069
,64287,DB01362,10015150,35,831,29,561,0.436875343,0.81488713,0.477763015,1.399322129,0.605434091,DB0136210015150_,0.501809573,-0.204705666,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,iohexol,DB01362
,64298,DB00175,10006093,21,8110,30,6076,0.023390587,0.524473031,0.285106807,0.948087663,0.069766986,DB0017510006093_,2.662594357,-0.645361271,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,pravastatin,DB00175
,64299,DB01156,10006093,55,13567,41,6287,0.027262352,0.621649991,0.40686358,0.956527388,0.078578187,DB0115610006093_,2.543661137,-0.475378059,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,bupropion,DB01156
,64302,DB00678,10009887,46,15553,27,10697,0.552496661,1.171730972,0.712758876,1.961513391,0.706341183,DB0067810009887_,0.347656896,0.158482119,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,64303,DB00999,10009887,52,21378,24,12215,0.406411925,1.238026757,0.74914813,2.101053593,0.576002234,DB0099910009887_,0.551643739,0.213518787,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,64307,DB01268,10011224,51,2092,81,3049,0.654785688,0.917656682,0.630484001,1.325068751,0.788502659,DB0126810011224_,0.2376195,-0.085931943,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sunitinib,DB01268
,64308,DB01136,10012174,158,9726,152,10963,0.169284575,1.171668168,0.930153596,1.476235277,0.309970302,DB0113610012174_,1.171278786,0.158428518,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,carvedilol,DB01136
,64310,DB00338,10028116,36,33638,36,22236,0.09116789,0.661061057,0.404590489,1.080020978,0.197115833,DB0033810028116_,1.623963739,-0.413909072,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,64315,DB01268,10028116,30,2113,39,3091,0.624156858,1.12524072,0.672752128,1.865143961,0.764045315,DB0126810028116_,0.269128179,0.117996986,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,64317,DB00996,10033553,35,38918,17,22408,0.666099346,1.18538696,0.646375206,2.256808389,0.796887775,DB0099610033553_,0.227041419,0.17006927,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,64318,DB00999,10033553,33,21397,27,12212,0.179511682,0.697598076,0.406519292,1.206654456,0.323259998,DB0099910033553_,1.129298332,-0.360112165,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,64325,DB01156,10047895,178,13444,88,6240,0.642627428,0.938848086,0.721839208,1.228535878,0.779054605,DB0115610047895_,0.249674139,-0.063101595,NA,10047895,Weight decreased,10022891,Investigations,Inv,bupropion,DB01156
,64327,DB00678,10054236,47,15552,25,10699,0.337401484,1.293333275,0.779479417,2.194181406,0.506588867,DB0067810054236_,0.680055517,0.25722282,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,losartan,DB00678
,64328,DB00996,10054236,133,38820,61,22364,0.155863604,1.256101333,0.920489344,1.730800878,0.291956162,DB0099610054236_,1.231151619,0.228012744,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,64329,DB00999,10054236,44,21386,24,12215,0.900218181,1.04714312,0.622637093,1.80145255,0.956657329,DB0099910054236_,0.04431002,0.046065617,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,64330,DB01136,10054236,40,9844,30,11085,0.094324343,1.501380012,0.91121383,2.498296702,0.202261001,DB0113610054236_,1.598196331,0.406384693,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,carvedilol,DB01136
,64333,DB00678,10061428,292,15307,190,10534,0.574655695,1.057633178,0.876472225,1.278661292,0.724362046,DB0067810061428_,0.322463948,0.05603356,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,64334,DB01136,10061428,190,9694,175,10940,0.056871292,1.225249008,0.990632284,1.516078064,0.137564621,DB0113610061428_,1.983661498,0.203144096,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,carvedilol,DB01136
,64335,DB00678,10061818,116,15483,94,10630,0.259217356,0.847252939,0.639144898,1.125543615,0.420341665,DB0067810061818_,0.866687411,-0.165755999,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,64336,DB01136,10061818,80,9804,98,11017,0.597992766,0.91735927,0.673210211,1.246896491,0.742985977,DB0113610061818_,0.297078107,-0.086256095,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,64337,DB01156,10061818,58,13564,18,6310,0.139918606,1.49895614,0.869772937,2.705729936,0.269729414,DB0115610061818_,1.310335992,0.404768959,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,64338,DB00158,10022437,222,16593,107,7997,1,0.999938965,0.789153162,1.273469692,1,DB0015810022437_,0,-6.10E-05,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,folic acid,DB00158
,64339,DB00158,10027175,146,16669,74,8030,0.7182446,0.950447837,0.712781048,1.276529248,0.833604562,DB0015810027175_,0.181996135,-0.050821999,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,64361,DB00682,10061284,37,19422,13,16351,0.006372506,2.395998006,1.244296776,4.914097689,0.024846298,DB0068210061284_,3.695046502,0.873799848,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,64369,DB01268,10003239,54,2089,88,3042,0.545296867,0.893570213,0.621682224,1.274443493,0.700089885,DB0126810003239_,0.356546544,-0.112530366,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sunitinib,DB01268
,64370,DB00295,10005191,32,14631,25,9577,0.501440607,0.837859923,0.480746755,1.475711758,0.662929602,DB0029510005191_,0.411086476,-0.176904349,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,morphine,DB00295
,64371,DB01050,10005191,54,18054,32,9339,0.569399567,0.872923009,0.55316541,1.398061933,0.720261201,DB0105010005191_,0.328141353,-0.135907918,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,64372,DB01268,10005191,91,2052,89,3041,0.006779109,1.515109467,1.112388331,2.064292884,0.026125488,DB0126810005191_,3.644843905,0.415487691,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,sunitinib,DB01268
,64374,DB01050,10031009,43,18065,12,9359,0.063467006,1.856392491,0.961112617,3.869249695,0.14971777,DB0105010031009_,1.89900329,0.618635083,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,64375,DB01268,10031009,152,1991,128,3002,2.44393786707658e-06,1.790233723,1.395879324,2.299063646,3.15437794432153e-05,DB0126810031009_,10.36413415,0.582346183,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,64377,DB00355,10011762,148,1645,126,1137,0.107988491,0.811931268,0.627992127,1.050859629,0.223054769,DB0035510011762_,1.500337937,-0.208339588,NA,10011762,Cystic fibrosis,10010331,"Congenital, familial and genetic disorders",Cong,aztreonam,DB00355
,64378,DB00355,10038695,40,1753,30,1233,0.806898314,0.937843091,0.566169393,1.568670136,0.895663944,DB0035510038695_,0.110189999,-0.064172625,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,aztreonam,DB00355
,64379,DB01296,10002034,32,1417,30,953,0.237780521,0.717498634,0.419094555,1.231229097,0.395260774,DB0129610002034_,0.928209544,-0.331984235,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,glucosamine,DB01296
,64380,DB01377,10002034,99,3697,65,2605,0.68855541,1.073201475,0.773662999,1.497205677,0.812273812,DB0137710002034_,0.207917789,0.070646214,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,magnesium oxide,DB01377
,64381,DB01394,10002034,20,1420,38,1965,0.284180002,0.728382918,0.399761553,1.289927206,0.44866933,DB0139410002034_,0.80146912,-0.316928383,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,colchicine,DB01394
,64384,DB00706,10002855,15,1060,144,15781,0.136846763,1.550737941,0.842828922,2.656043403,0.265286317,DB0070610002855_,1.326945596,0.438730909,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,tamsulosin,DB00706
,64388,DB00973,10012378,45,3806,27,2994,0.284681925,1.311035768,0.793934972,2.202993874,0.4492193,DB0097310012378_,0.800244092,0.270817487,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ezetimibe,DB00973
,64417,DB00381,10028810,475,28885,191,22696,6.67931061360401e-16,1.954010957,1.646933973,2.325763357,4.53658086507962e-14,DB0038110028810_,30.72401769,0.669884161,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,amlodipine,DB00381
,64418,DB00722,10028810,319,25084,179,25853,4.83933415229778e-11,1.836722906,1.523451828,2.22007588,1.66059919312203e-09,DB0072210028810_,20.21608734,0.607982954,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,lisinopril,DB00722
,64419,DB00252,10044565,41,2191,22,1886,0.075813665,1.604025109,0.92955232,2.838328689,0.171183532,DB0025210044565_,1.765019012,0.472516163,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,phenytoin,DB00252
,64420,DB06403,10044565,109,21362,33,6628,1,1.024840373,0.687902423,1.563953279,1,DB0640310044565_,0,0.024536867,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,64421,DB14500,10044565,80,7729,26,4047,0.039253393,1.611055254,1.021809057,2.61797422,0.104140847,DB1450010044565_,2.262011,0.476889402,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,potassium,DB14500
,64422,DB00181,10013709,441,9415,195,5676,0.00036834,1.363382211,1.145484167,1.6274041,0.00239412,DB0018110013709_,6.034739649,0.309968532,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,64423,DB00211,10013709,71,1365,95,1536,0.299060779,0.841042748,0.604073196,1.166637051,0.465040528,DB0021110013709_,0.76563072,-0.173112791,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,midodrine,DB00211
,64424,DB00281,10013709,528,10930,374,5297,7.0205429083373e-08,0.684180283,0.595698409,0.786442634,1.31388373332607e-06,DB0028110013709_,13.54252312,-0.379533824,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,64425,DB00535,10013709,39,1165,16,630,0.392039246,1.317944571,0.712971721,2.547595297,0.561949643,DB0053510013709_,0.576343037,0.27607338,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cefdinir,DB00535
,64426,DB00687,10013709,79,907,67,1018,0.121624742,1.323217455,0.931262027,1.884634136,0.243731662,DB0068710013709_,1.411687407,0.280066236,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fludrocortisone,DB00687
,64501,DB01075,10057362,58,19890,17,11080,0.021219074,1.900534005,1.09078137,3.483460319,0.064801134,DB0107510057362_,2.736432172,0.642134902,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,64517,DB00181,10063829,65,9791,50,5821,0.176383681,0.772911091,0.525563708,1.142532481,0.319179722,DB0018110063829_,1.142000944,-0.257591255,NA,10063829,Device malfunction,10077536,Product issues,Prod,baclofen,DB00181
,64520,DB00316,10063829,77,65397,30,36923,0.087327768,1.449129038,0.938908618,2.289931153,0.190640786,DB0031610063829_,1.657364322,0.370962712,NA,10063829,Device malfunction,10077536,Product issues,Prod,acetaminophen,DB00316
,64560,DB00181,10070305,32,9824,40,5831,0.002044238,0.474852523,0.28839102,0.776162514,0.009897368,DB0018110070305_,4.615486462,-0.744751001,NA,10070305,Device kink,10077536,Product issues,Prod,baclofen,DB00181
,64593,DB01373,10036653,39,22681,11,7370,0.745098422,1.152058259,0.578260424,2.495347578,0.854485157,DB0137310036653_,0.157256147,0.141550133,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,calcium,DB01373
,64596,DB00213,10003445,67,18828,59,13362,0.239486483,0.805927987,0.559007393,1.164506065,0.397319343,DB0021310003445_,0.923014932,-0.215760886,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,64598,DB00904,10003445,112,22957,69,14387,0.939106598,1.017241584,0.746416584,1.394802723,0.97872475,DB0090410003445_,0.02150483,0.017094635,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,64602,DB00646,10007882,49,3404,26,1974,0.809560234,1.092893974,0.663644833,1.838134264,0.897384007,DB0064610007882_,0.108271407,0.088829199,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,nystatin,DB00646
,64603,DB00904,10007882,185,22884,112,14344,0.810868452,1.035363104,0.813590916,1.322499842,0.898226748,DB0090410007882_,0.107332739,0.03475219,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,64605,DB01225,10007882,59,4985,47,4593,0.494426364,1.156587993,0.773294389,1.73833225,0.656944117,DB0122510007882_,0.420156323,0.145474286,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,enoxaparin,DB01225
,64608,DB00646,10013968,163,3290,105,1895,0.398319924,0.894173885,0.690683228,1.161665872,0.568117598,DB0064610013968_,0.565426844,-0.111855021,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nystatin,DB00646
,64609,DB01043,10013968,36,1365,44,1366,0.427565131,0.818840781,0.508618897,1.310706521,0.596136201,DB0104310013968_,0.517286113,-0.19986562,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,memantine,DB01043
,64610,DB01043,10021097,16,1385,38,1372,0.003523211,0.417206781,0.21613081,0.770580066,0.01540379,DB0104310021097_,4.173141667,-0.874173302,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,memantine,DB01043
,64611,DB06186,10021097,66,2143,83,3563,0.103682465,1.32199216,0.937705973,1.857573174,0.216516533,DB0618610021097_,1.53008837,0.279139811,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ipilimumab,DB06186
,64632,DB01225,10051398,29,5015,54,4586,0.001878931,0.491136327,0.300987055,0.786706756,0.009248634,DB0122510051398_,4.683279439,-0.711033539,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,enoxaparin,DB01225
,64634,DB00213,10062237,104,18791,96,13325,0.071706475,0.768223958,0.575956283,1.025575741,0.164253134,DB0021310062237_,1.806346544,-0.263673976,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,64637,DB00904,10062237,81,22988,77,14379,0.010858919,0.658023171,0.475308583,0.911544272,0.038029002,DB0090410062237_,3.269406204,-0.418515134,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,ondansetron,DB00904
,64642,DB00421,10007515,83,8820,88,5164,0.00012308,0.552270795,0.40333508,0.755617386,0.000952639,DB0042110007515_,6.956274231,-0.593716782,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,spironolactone,DB00421
,64643,DB01175,10007515,98,10626,51,4841,0.477725438,0.875445252,0.616803608,1.255544595,0.643042536,DB0117510007515_,0.441544404,-0.133022662,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,escitalopram,DB01175
,64650,DB00374,10019641,38,17678,15,5709,0.522486839,0.818116893,0.439267446,1.602259497,0.681010004,DB0037410019641_,0.384178282,-0.200750052,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,treprostinil,DB00374
,64651,DB00421,10019641,69,8834,66,5186,0.005376838,0.613784069,0.430771962,0.875157501,0.021676171,DB0042110019641_,3.831541749,-0.488112092,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,spironolactone,DB00421
,64652,DB00820,10019641,49,11866,22,5794,0.801035011,1.087538566,0.644563559,1.890777233,0.892358774,DB0082010019641_,0.113887015,0.083916947,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,tadalafil,DB00820
,64654,DB06403,10019641,31,21440,22,6639,0.005159404,0.436343431,0.244442989,0.791533341,0.020975166,DB0640310019641_,3.864416127,-0.829325661,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,ambrisentan,DB06403
,64662,DB00820,10024714,33,11882,20,5796,0.464898285,0.804894464,0.447945989,1.481551529,0.631778069,DB0082010024714_,0.459217102,-0.217044111,NA,10024714,Liver transplant,10042613,Surgical and medical procedures,Surg,tadalafil,DB00820
,64671,DB00335,10037377,60,8406,48,5417,0.277240712,0.805546946,0.541037099,1.204960589,0.440784644,DB0033510037377_,0.819198858,-0.216233796,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atenolol,DB00335
,64672,DB00335,10061818,78,8388,60,5405,0.335194844,0.837701244,0.589541954,1.195412993,0.504400855,DB0033510061818_,0.684383979,-0.177093753,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,64703,DB09020,10033371,80,1874,32,1572,0.000328205,2.096656732,1.367045687,3.28477853,0.002172467,DB0902010033371_,6.13189209,0.740344044,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,bisacodyl,DB09020
,64721,DB00996,10064684,48,38905,12,22413,0.007054849,2.304351155,1.205499015,4.766417452,0.026953008,DB0099610064684_,3.613660359,0.834799142,NA,10064684,Device dislocation,10077536,Product issues,Prod,gabapentin,DB00996
,64724,DB00181,10069868,62,9794,67,5804,0.000922874,0.548429288,0.381260324,0.787737707,0.005157383,DB0018110069868_,5.267326068,-0.600696926,NA,10069868,Device issue,10077536,Product issues,Prod,baclofen,DB00181
,64727,DB00404,10069868,52,19840,8,9854,0.000814908,3.228276068,1.52219207,7.874126279,0.004649922,DB0040410069868_,5.370904804,1.17194827,female,10069868,Device issue,10077536,Product issues,Prod,alprazolam,DB00404
,64746,DB00635,10004146,25,33028,32,23762,0.031679256,0.56208925,0.319230427,0.979177976,0.088398597,DB0063510004146_,2.425899184,-0.576094633,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,64749,DB00996,10004146,43,38910,32,22393,0.281377558,0.77335801,0.47793552,1.263167886,0.445341342,DB0099610004146_,0.80891423,-0.257013194,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,gabapentin,DB00996
,64751,DB01373,10004146,34,22686,19,7362,0.076779543,0.580727654,0.321735438,1.078430672,0.172831231,DB0137310004146_,1.755439702,-0.543473386,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,calcium,DB01373
,64753,DB00327,10018884,51,6087,36,4226,1,0.983541052,0.628254961,1.554258747,1,DB0032710018884_,0,-0.016595901,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,hydromorphone,DB00327
,64754,DB00741,10018884,35,4059,31,3143,0.619110566,0.874259931,0.522363836,1.469647609,0.75999337,DB0074110018884_,0.27444557,-0.134377543,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,hydrocortisone,DB00741
,64757,DB00497,10029366,76,19191,60,16315,0.730400574,1.076864379,0.75700583,1.53778268,0.84315587,DB0049710029366_,0.170603439,0.074053466,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,oxycodone,DB00497
,64758,DB00635,10029366,60,32993,78,23716,0.000695832,0.552956449,0.388037675,0.784574912,0.004071669,DB0063510029366_,5.503702262,-0.592476035,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,prednisone,DB00635
,64760,DB00996,10029366,89,38864,51,22374,1,1.004652685,0.703958182,1.447302442,1,DB0099610029366_,0,0.004641895,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,gabapentin,DB00996
,64761,DB01075,10029366,58,19890,44,11053,0.121550697,0.732553895,0.486169299,1.110610506,0.243648294,DB0107510029366_,1.412029512,-0.311218364,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,diphenhydramine,DB01075
,64762,DB01373,10029366,80,22640,28,7353,0.737046108,0.927935118,0.596128416,1.483833213,0.848327581,DB0137310029366_,0.16448842,-0.074793465,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,calcium,DB01373
,64765,DB00635,10034754,41,33012,10,23784,0.000979219,2.953811361,1.454772197,6.613300925,0.005411834,DB0063510034754_,5.21916716,1.083096323,female,10034754,Petechiae,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,64774,DB00904,10040882,51,23018,26,14430,0.41433196,1.22965206,0.752149819,2.055712444,0.583608359,DB0090410040882_,0.53852514,0.206731252,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,64788,DB01088,10011224,116,1313,29,408,0.358251064,1.242803533,0.807364842,1.967016866,0.527971138,DB0108810011224_,0.63871366,0.217369742,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iloprost,DB01088
,64789,DB00820,10015150,153,11762,48,5768,0.006429759,1.563090658,1.121575265,2.212878995,0.025015724,DB0082010015150_,3.688250711,0.446665052,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,tadalafil,DB00820
,64793,DB00820,10024264,59,11856,41,5775,0.08741085,0.700937184,0.462056394,1.072456687,0.190798389,DB0082010024264_,1.656537962,-0.355337005,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,64795,DB00820,10024774,63,11852,21,5795,0.131706007,1.466811485,0.881856867,2.533899503,0.258176776,DB0082010024774_,1.354110749,0.383090987,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,tadalafil,DB00820
,64797,DB00820,10027175,117,11798,48,5768,0.3189887,1.191654992,0.84336192,1.706849772,0.487109626,DB0082010027175_,0.719266077,0.17534309,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,64799,DB01088,10028813,90,1339,17,420,0.060198133,1.660261807,0.967868181,3.009933592,0.14383892,DB0108810028813_,1.939061218,0.506975305,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,iloprost,DB01088
,64803,DB01088,10047700,56,1373,7,430,0.021970215,2.504665545,1.127454459,6.563736596,0.066561445,DB0108810047700_,2.709629773,0.918155211,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,iloprost,DB01088
,64804,DB00820,10048294,46,11869,23,5793,0.898550688,0.976139196,0.578988781,1.689027031,0.956423691,DB0082010048294_,0.044554273,-0.024150084,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,tadalafil,DB00820
,64808,DB00047,10061024,45,9240,56,8462,0.13447593,0.735928056,0.48518082,1.110680956,0.261926627,DB0004710061024_,1.339690864,-0.306622916,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,insulin glargine,DB00047
,64809,DB08895,10061024,62,28052,20,6626,0.259175297,0.732240776,0.435888121,1.280907806,0.420286427,DB0889510061024_,0.866818832,-0.311645891,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,tofacitinib,DB08895
,64814,DB00624,10020772,6,556,56,4340,0.840841644,0.836385197,0.293085306,1.949704276,0.918695734,DB0062410020772_,0.084800295,-0.17866601,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,testosterone,DB00624
,64826,DB00046,10001551,20,5439,38,4654,0.003471825,0.450385592,0.247949718,0.794983176,0.015223443,DB0004610001551_,4.184918749,-0.797651192,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,insulin lispro,DB00046
,64827,DB00047,10001551,25,9260,38,8480,0.057410678,0.602500512,0.348257839,1.025384391,0.138552053,DB0004710001551_,1.976509193,-0.506666765,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,insulin glargine,DB00047
,64830,DB00471,10001551,45,14144,18,5447,0.888397603,0.962775789,0.545774559,1.768798883,0.953785525,DB0047110001551_,0.04731645,-0.03793472,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,montelukast,DB00471
,64837,DB00030,10002034,35,2171,18,1803,0.125736402,1.614658,0.886532729,3.039346599,0.249677519,DB0003010002034_,1.387585119,0.47912317,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,insulin human,DB00030
,64843,DB00046,10003481,17,5442,34,4658,0.00441238,0.428000461,0.223934494,0.788847181,0.018485718,DB0004610003481_,3.99075682,-0.848631006,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,insulin lispro,DB00046
,64844,DB00047,10003481,26,9259,34,8484,0.195709068,0.700716811,0.403436701,1.20395168,0.343907555,DB0004710003481_,1.067382392,-0.355651452,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,insulin glargine,DB00047
,64847,DB00207,10003481,44,9036,77,5378,6.95337835203021e-09,0.340125776,0.228966463,0.499757398,1.61671428556492e-07,DB0020710003481_,15.63769978,-1.078439802,male,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,azithromycin,DB00207
,64848,DB00471,10003481,42,14147,14,5451,0.765384421,1.155921487,0.618245417,2.293719598,0.870556676,DB0047110003481_,0.138622415,0.144897851,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,montelukast,DB00471
,64850,DB06403,10003481,48,21423,16,6645,0.769810301,0.930536534,0.518789195,1.756737082,0.873945656,DB0640310003481_,0.134737084,-0.071993941,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,ambrisentan,DB06403
,64858,DB00169,10005287,35,38656,15,18160,0.879724566,1.096160337,0.583195096,2.160843428,0.949457398,DB0016910005287_,0.051864617,0.09181347,NA,10005287,Blood albumin decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,64870,DB00169,10005395,85,38606,34,18141,0.491068514,1.174737289,0.780324533,1.804630105,0.654251908,DB0016910005395_,0.424262822,0.161044539,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,64872,DB00338,10005395,53,33621,30,22242,0.575018728,1.168698732,0.733004648,1.895204851,0.724631665,DB0033810005395_,0.322091802,0.155890935,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,omeprazole,DB00338
,64910,DB00153,10005557,59,7364,29,3410,0.81822463,0.942101017,0.593096782,1.527236502,0.902973986,DB0015310005557_,0.102061534,-0.059642773,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,ergocalciferol,DB00153
,64911,DB00207,10005557,39,9041,27,5428,0.610836299,0.867222864,0.516844186,1.474937735,0.752932427,DB0020710005557_,0.283779794,-0.142459284,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,azithromycin,DB00207
,64913,DB06403,10005557,30,21441,23,6638,0.001715924,0.40383293,0.226635239,0.728521038,0.00857269,DB0640310005557_,4.75917367,-0.906754027,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,ambrisentan,DB06403
,64934,DB00471,10005724,51,14138,14,5451,0.331247689,1.404460957,0.764951541,2.749989605,0.499991129,DB0047110005724_,0.693164923,0.339653568,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,montelukast,DB00471
,64937,DB06403,10005724,100,21371,7,6654,3.65224730339403e-06,4.447867129,2.079275541,11.3530294,4.48971541532459e-05,DB0640310005724_,10.01113615,1.492424684,female,10005724,Blood potassium decreased,10022891,Investigations,Inv,ambrisentan,DB06403
,64982,DB00003,10010264,108,2890,81,2512,0.335506252,1.158907867,0.856265111,1.573652865,0.50470973,DB0000310010264_,0.683771807,0.147478067,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,dornase alfa,DB00003
,64984,DB00046,10010264,87,5372,46,4646,0.006626483,1.635621667,1.128813616,2.397216422,0.025644451,DB0004610010264_,3.663428071,0.492022956,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,64985,DB00047,10010264,148,9137,100,8418,0.017798186,1.363510052,1.048919103,1.77856609,0.056381478,DB0004710010264_,2.875614586,0.310062296,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,64987,DB00153,10010264,153,7270,60,3379,0.29771477,1.185172996,0.871162372,1.63018379,0.463633187,DB0015310010264_,0.768661586,0.169888752,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,64988,DB00207,10010264,145,8935,95,5360,0.502389722,0.915625599,0.700413094,1.201581184,0.663633633,DB0020710010264_,0.41002504,-0.088147732,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,64989,DB00684,10010264,112,2680,83,2265,0.380263365,1.14041062,0.845958127,1.542440308,0.55035226,DB0068410010264_,0.597196734,0.13138839,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,tobramycin,DB00684
,64991,DB14512,10010264,69,4775,20,2392,0.031238688,1.728133604,1.035032312,3.009702995,0.087440383,DB1451210010264_,2.436798053,0.547041985,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,64992,DB00003,10011224,142,2856,129,2464,0.708055271,0.94967097,0.738240129,1.222606204,0.825584719,DB0000310011224_,0.191663393,-0.051639701,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dornase alfa,DB00003
,64994,DB00684,10011224,160,2632,120,2228,0.354856849,1.128637859,0.878961199,1.452231865,0.524660382,DB0068410011224_,0.645004117,0.121011471,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tobramycin,DB00684
,65011,DB00003,10011762,221,2777,194,2399,0.878179339,0.984112777,0.801427484,1.209174218,0.948451728,DB0000310011762_,0.052924384,-0.016014778,NA,10011762,Cystic fibrosis,10010331,"Congenital, familial and genetic disorders",Cong,dornase alfa,DB00003
,65017,DB00169,10011762,53,38638,32,18143,0.294546612,0.7777471,0.492117605,1.246979303,0.460395541,DB0016910011762_,0.775669286,-0.251353872,NA,10011762,Cystic fibrosis,10010331,"Congenital, familial and genetic disorders",Cong,cholecalciferol,DB00169
,65018,DB00207,10011762,88,8992,56,5399,0.730189796,0.943525465,0.66609882,1.346037021,0.843038622,DB0020710011762_,0.170742507,-0.058131924,NA,10011762,Cystic fibrosis,10010331,"Congenital, familial and genetic disorders",Cong,azithromycin,DB00207
,65019,DB00338,10011762,35,33639,25,22247,0.792665924,0.925885621,0.538405528,1.614302586,0.88758728,DB0033810011762_,0.119248419,-0.077004572,NA,10011762,Cystic fibrosis,10010331,"Congenital, familial and genetic disorders",Cong,omeprazole,DB00338
,65020,DB00471,10011762,44,14145,19,5446,0.673768639,0.891621569,0.509312728,1.618512533,0.802138219,DB0047110011762_,0.220474343,-0.114713486,NA,10011762,Cystic fibrosis,10010331,"Congenital, familial and genetic disorders",Cong,montelukast,DB00471
,65021,DB00684,10011762,163,2629,162,2186,0.120760163,0.836659327,0.663915256,1.054408023,0.242526045,DB0068410011762_,1.416646174,-0.178338308,NA,10011762,Cystic fibrosis,10010331,"Congenital, familial and genetic disorders",Cong,tobramycin,DB00684
,65028,DB00047,10012601,83,9202,63,8455,0.279670395,1.210497298,0.860704356,1.709622854,0.443494092,DB0004710012601_,0.813070798,0.191031265,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,insulin glargine,DB00047
,65030,DB00153,10012601,30,7393,24,3415,0.055403094,0.577428104,0.325785196,1.03381047,0.135014499,DB0015310012601_,2.002373103,-0.54917134,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,ergocalciferol,DB00153
,65032,DB00471,10012601,38,14151,22,5443,0.147906971,0.664388353,0.382649535,1.180495526,0.281068157,DB0047110012601_,1.269158089,-0.408888431,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,montelukast,DB00471
,65034,DB01306,10012601,49,4159,41,3825,0.67276673,1.099107272,0.709268391,1.711069705,0.801399144,DB0130610012601_,0.221396149,0.09449828,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,insulin aspart,DB01306
,65052,DB00003,10016256,59,2939,48,2545,0.769924883,1.064393483,0.711979555,1.598107124,0.873962496,DB0000310016256_,0.134717815,0.062405137,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dornase alfa,DB00003
,65054,DB00684,10016256,77,2715,45,2303,0.053266996,1.451344415,0.98745992,2.15511934,0.131116074,DB0068410016256_,2.031672288,0.372490309,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tobramycin,DB00684
,65074,DB00047,10017885,30,9255,38,8480,0.223676889,0.723381683,0.432405143,1.20017153,0.378113493,DB0004710017885_,0.972560882,-0.323818281,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,65076,DB00471,10017885,111,14078,36,5429,0.406182561,1.189030286,0.808652917,1.785751118,0.575754772,DB0047110017885_,0.552073452,0.173138089,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,65079,DB06403,10017885,127,21344,30,6631,0.188418808,1.315158371,0.876838716,2.030769633,0.334540913,DB0640310017885_,1.094996096,0.273957093,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,65085,DB00047,10017944,40,9245,25,8493,0.136948821,1.469817702,0.869233675,2.53041824,0.265425436,DB0004710017944_,1.326421321,0.385138381,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,65087,DB00169,10017944,222,38469,67,18108,0.001219529,1.5596768,1.18111591,2.082886438,0.006483028,DB0016910017944_,5.038567658,0.44447862,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,65088,DB00207,10017944,51,9029,24,5431,0.341429821,1.278184745,0.771426083,2.173975621,0.510610084,DB0020710017944_,0.672149025,0.245440903,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,65089,DB00471,10017944,62,14127,19,5446,0.456033479,1.257927107,0.741433627,2.22992858,0.623389239,DB0047110017944_,0.472584173,0.229465213,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,65092,DB06403,10017944,115,21356,32,6629,0.627813033,1.115511322,0.747500184,1.70801379,0.767163272,DB0640310017944_,0.265055629,0.109312884,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,65098,DB00471,10018964,38,14151,30,5435,0.004083647,0.486495071,0.293212369,0.814010102,0.01737434,DB0047110018964_,4.052760882,-0.720528508,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,65107,DB00338,10019022,59,33615,41,22231,0.838236881,0.9517074,0.627934886,1.454707293,0.916840664,DB0033810019022_,0.086821579,-0.049497645,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,65119,DB00169,10019708,47,38644,14,18161,0.168686176,1.577699505,0.853662077,3.103843629,0.309091401,DB0016910019708_,1.174118251,0.455967776,NA,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,cholecalciferol,DB00169
,65121,DB00338,10019708,41,33633,23,22249,0.609768733,1.17919813,0.690959307,2.05922375,0.752071471,DB0033810019708_,0.284923919,0.164834657,NA,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,omeprazole,DB00338
,65157,DB00003,10025082,38,2960,30,2563,0.715898633,1.096728303,0.659593657,1.838888026,0.831891935,DB0000310025082_,0.184052733,0.092331478,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dornase alfa,DB00003
,65163,DB00169,10025082,86,38605,47,18128,0.403188482,0.859237692,0.59506553,1.254187802,0.572931978,DB0016910025082_,0.556988282,-0.151709687,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,65164,DB00207,10025082,34,9046,31,5424,0.095865017,0.657672814,0.391711871,1.10785818,0.204588315,DB0020710025082_,1.586755539,-0.419047714,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,65165,DB00338,10025082,97,33577,53,22219,0.278337812,1.211066525,0.85741768,1.727026916,0.442155177,DB0033810025082_,0.816094379,0.191501397,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,65166,DB00471,10025082,54,14135,25,5440,0.451215992,0.831332568,0.507895059,1.395602564,0.61889594,DB0047110025082_,0.47981813,-0.184725362,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,65167,DB00684,10025082,40,2752,33,2315,1,1.019642148,0.624718473,1.67458318,1,DB0068410025082_,0,0.01945173,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tobramycin,DB00684
,65171,DB00003,10025482,67,2931,66,2527,0.4817608,0.875248202,0.610913721,1.254221749,0.646292647,DB0000310025482_,0.436502863,-0.133247774,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,dornase alfa,DB00003
,65172,DB00030,10025482,61,2145,46,1775,0.694089375,1.097283578,0.732033611,1.654681196,0.815819199,DB0003010025482_,0.203562519,0.092837651,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,insulin human,DB00030
,65174,DB00471,10025482,477,13712,116,5349,3.04552943367768e-06,1.604088239,1.303434609,1.987345002,3.84217620178631e-05,DB0047110025482_,10.16688654,0.47255552,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,65176,DB00003,10035664,151,2847,138,2455,0.67166567,0.943581646,0.739197443,1.205143422,0.800776157,DB0000310035664_,0.222173826,-0.058072383,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,dornase alfa,DB00003
,65177,DB00030,10035664,64,2142,58,1763,0.644468768,0.908229359,0.62285501,1.326671869,0.780476932,DB0003010035664_,0.247850094,-0.096258334,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,insulin human,DB00030
,65178,DB00046,10035664,185,5274,162,4530,0.869586378,0.980875333,0.787000538,1.223478246,0.942026112,DB0004610035664_,0.059722285,-0.019309909,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,insulin lispro,DB00046
,65194,DB00003,10037660,50,2948,56,2537,0.201149297,0.768418699,0.512068145,1.150361098,0.350355131,DB0000310037660_,1.048807979,-0.263420513,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,dornase alfa,DB00003
,65195,DB00030,10037660,29,2177,30,1791,0.429762952,0.795318229,0.458698136,1.377044151,0.598274459,DB0003010037660_,0.513705669,-0.229012957,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,insulin human,DB00030
,65197,DB01306,10037660,74,4134,70,3796,0.866744901,0.970705513,0.688387153,1.369931153,0.93988695,DB0130610037660_,0.061995677,-0.029732139,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,65199,DB14512,10037660,78,4766,30,2382,0.257733886,1.299448878,0.84013614,2.057488886,0.418594611,DB1451210037660_,0.870852342,0.261940235,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,65234,DB00338,10042209,148,33526,42,22230,3.2863187354636e-07,2.336479435,1.647904085,3.376501668,5.30432225739397e-06,DB0033810042209_,12.14698855,0.848645281,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,65235,DB00471,10042209,81,14108,20,5445,0.075172978,1.563130295,0.947807235,2.695541075,0.170140071,DB0047110042209_,1.771133233,0.44669041,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,montelukast,DB00471
,65261,DB00338,10047626,45,33629,20,22252,0.162904222,1.488793216,0.8610016,2.662429259,0.301244348,DB0033810047626_,1.199833557,0.39796587,NA,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,65298,DB00003,10047895,44,2954,41,2552,0.743433093,0.927150307,0.589850695,1.460116133,0.85328758,DB0000310047895_,0.158658649,-0.075639583,NA,10047895,Weight decreased,10022891,Investigations,Inv,dornase alfa,DB00003
,65299,DB00030,10047895,39,2167,37,1784,0.56215683,0.867790609,0.536565422,1.405808213,0.714426611,DB0003010047895_,0.336275001,-0.141804827,NA,10047895,Weight decreased,10022891,Investigations,Inv,insulin human,DB00030
,65300,DB00046,10047895,88,5371,89,4603,0.287472573,0.847396237,0.62218249,1.15402272,0.452373251,DB0004610047895_,0.793247664,-0.165586882,NA,10047895,Weight decreased,10022891,Investigations,Inv,insulin lispro,DB00046
,65303,DB14512,10047895,68,4776,32,2380,0.831466791,1.058931466,0.683806503,1.67127906,0.911921247,DB1451210047895_,0.092201645,0.057260349,NA,10047895,Weight decreased,10022891,Investigations,Inv,mometasone furoate,DB14512
,65307,DB00047,10047924,39,9246,26,8492,0.215657757,1.377648629,0.816887347,2.359227081,0.368233021,DB0004710047924_,0.999039332,0.320378154,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,65309,DB00153,10047924,44,7379,8,3431,0.010564026,2.557143465,1.189076921,6.295895677,0.037184523,DB0015310047924_,3.29186264,0.938890802,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,65310,DB00338,10047924,136,33538,71,22201,0.117432073,1.267977487,0.944339209,1.715068824,0.237305443,DB0033810047924_,1.43840718,0.237423101,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,65320,DB00169,10048908,135,38556,50,18125,0.155862488,1.26921603,0.910710162,1.793824119,0.291956162,DB0016910048908_,1.231151619,0.238399411,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,cholecalciferol,DB00169
,65322,DB00338,10048908,86,33588,43,22229,0.149567532,1.323620458,0.907230454,1.956658016,0.283363311,DB0033810048908_,1.261025421,0.280370753,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,omeprazole,DB00338
,65323,DB00471,10048908,63,14126,18,5447,0.319903974,1.349551902,0.788122068,2.424289407,0.488067792,DB0047110048908_,0.717300965,0.299772613,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,montelukast,DB00471
,65326,DB06403,10048908,55,21416,11,6650,0.195046885,1.552521361,0.80312984,3.291715279,0.34304499,DB0640310048908_,1.069893675,0.439880294,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,ambrisentan,DB06403
,65418,DB00169,10060945,30,38661,23,18152,0.078184458,0.612412211,0.343855622,1.104323592,0.175310597,DB0016910060945_,1.741196039,-0.490349676,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,65420,DB00338,10060945,43,33631,25,22247,0.710266242,1.137815043,0.679191105,1.944502705,0.827193699,DB0033810060945_,0.189716393,0.129109794,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,65445,DB00169,10061273,45,38646,29,18146,0.211698805,0.728586766,0.446777028,1.205514797,0.3634792,DB0016910061273_,1.012033204,-0.316648558,NA,10061273,Malnutrition,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,65447,DB00338,10061273,45,33629,22,22250,0.263067712,1.353329059,0.795602615,2.36725887,0.424868498,DB0033810061273_,0.855975575,0.302567527,NA,10061273,Malnutrition,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,65453,DB00003,10061471,35,2963,33,2560,0.806927597,0.916366916,0.551306588,1.526201074,0.895666483,DB0000310061471_,0.110187164,-0.087338431,NA,10061471,Pseudomonas infection,10021881,Infections and infestations,Infec,dornase alfa,DB00003
,65460,DB00207,10061471,24,9056,31,5424,0.004968844,0.46371418,0.260113851,0.817277556,0.020356308,DB0020710061471_,3.894364436,-0.768486908,NA,10061471,Pseudomonas infection,10021881,Infections and infestations,Infec,azithromycin,DB00207
,65463,DB00684,10061471,43,2749,50,2298,0.116465515,0.718961556,0.465030282,1.107438222,0.235819902,DB0068410061471_,1.444686891,-0.329947392,NA,10061471,Pseudomonas infection,10021881,Infections and infestations,Infec,tobramycin,DB00684
,65551,DB01164,10011224,31,6493,26,7910,0.182446877,1.452457334,0.83364889,2.549717059,0.326988693,DB0116410011224_,1.117829688,0.373256835,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium chloride,DB01164
,65558,DB00264,10013971,171,29436,107,24785,0.015795821,1.34561066,1.050026517,1.730774567,0.051340813,DB0026410013971_,2.969269264,0.296847933,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,65559,DB00588,10019303,113,16411,32,8436,0.002636004,1.815183605,1.215347821,2.781283573,0.01216742,DB0058810019303_,4.408993392,0.596186622,NA,10019303,Heart rate increased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,65560,DB01076,10019303,136,25611,77,25506,6.2898156922637e-05,1.758962795,1.319706957,2.358919398,0.000536405,DB0107610019303_,7.530621467,0.564724314,NA,10019303,Heart rate increased,10022891,Investigations,Inv,atorvastatin,DB01076
,65561,DB00316,10025082,141,65333,66,36887,0.218700651,1.206153137,0.894015014,1.641693308,0.37195384,DB0031610025082_,0.988985518,0.187436069,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,65562,DB01076,10025082,60,25687,48,25535,0.289556325,1.24259561,0.835625899,1.856544652,0.454705087,DB0107610025082_,0.78810623,0.217202426,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,65573,DB00788,10012378,199,9157,57,5004,8.53573992794768e-06,1.907763559,1.411515549,2.613616315,9.45677235009925e-05,DB0078810012378_,9.266194329,0.645931644,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,naproxen,DB00788
,65575,DB00788,10022116,85,9271,8,5053,4.72271483942849e-09,5.791178618,2.806140342,13.85132971,1.14096102531597e-07,DB0078810022116_,15.98622474,1.756335832,female,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,65580,DB00788,10049119,44,9312,10,5051,0.009788503,2.386516564,1.182080802,5.323125598,0.034991271,DB0078810049119_,3.35265666,0.869834798,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,naproxen,DB00788
,65589,DB00480,10017413,1803,65625,1524,66138,6.09194989301894e-07,1.192315857,1.11212957,1.278449015,9.22389993882505e-06,DB0048010017413_,11.59371262,0.175897514,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,65590,DB00480,10024264,75,67353,122,67540,0.000992805,0.61646674,0.455999297,0.82875792,0.005468544,DB0048010024264_,5.208742953,-0.483750908,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,65593,DB09539,10012735,35,632,46,634,0.253525262,0.763432464,0.470494948,1.229412599,0.414044972,DB0953910012735_,0.881780682,-0.269930614,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,omega-3-acid ethyl esters,DB09539
,65594,DB00678,10069327,91,15508,47,10677,0.118099104,1.333006082,0.926578102,1.939866405,0.23832898,DB0067810069327_,1.434103292,0.287436604,NA,10069327,Product quality issue,10077536,Product issues,Prod,losartan,DB00678
,65610,DB06228,10019016,132,15780,137,15939,0.854339348,0.973207604,0.759603867,1.246532132,0.929175346,DB0622810019016_,0.073457811,-0.027157855,NA,10019016,Haemorrhagic stroke,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,65611,DB06228,10009033,66,15846,65,16011,0.930305293,1.02596181,0.716739413,1.469010403,0.971516672,DB0622810009033_,0.028896849,0.025630524,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,65612,DB06228,10037423,62,15850,24,16052,3.15847566081999e-05,2.616298869,1.608466797,4.385015633,0.00029682,DB0622810037423_,8.12238492,0.961760674,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,65614,DB01088,10021097,72,1357,16,421,0.301594856,1.395834637,0.793433838,2.6003269,0.467901479,DB0108810021097_,0.759497521,0.333492542,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,iloprost,DB01088
,65615,DB08932,10033318,816,18627,284,6313,0.696974655,0.973788519,0.847114118,1.121930035,0.817691928,DB0893210033318_,0.20126963,-0.026561125,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,macitentan,DB08932
,65616,DB00104,10000081,56,1425,31,1046,0.225945805,1.32585505,0.833530109,2.143765357,0.380822981,DB0010410000081_,0.96542063,0.282057572,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,octreotide,DB00104
,65623,DB00112,10010774,240,5693,139,3952,0.09871876,1.198563137,0.964550293,1.493868608,0.208914506,DB0011210010774_,1.565830174,0.181123454,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,65624,DB00544,10010774,53,2382,57,2596,1,1.013359506,0.68077041,1.506161547,1,DB0054410010774_,0,0.013271055,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,fluorouracil,DB00544
,65625,DB00650,10010774,38,2093,42,1972,0.499633219,0.852490043,0.532465015,1.36095936,0.661372159,DB0065010010774_,0.413438574,-0.15959375,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,leucovorin,DB00650
,65626,DB00762,10010774,39,1124,46,1323,1,0.99793132,0.629279873,1.575620919,1,DB0076210010774_,0,-0.002070822,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,irinotecan,DB00762
,65643,DB00213,10022687,66,18829,34,13387,0.128837252,1.380118845,0.898666373,2.154602631,0.253945271,DB0021310022687_,1.370636503,0.322169615,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,65648,DB00104,10028813,96,1385,52,1025,0.086135449,1.366123016,0.954894918,1.97279002,0.188578233,DB0010410028813_,1.668242329,0.311976813,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,octreotide,DB00104
,65649,DB00104,10047700,49,1432,27,1050,0.288436285,1.330549223,0.809404542,2.229677647,0.453455411,DB0010410047700_,0.790858336,0.285591807,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,octreotide,DB00104
,65652,DB13867,10013573,177,4373,78,2476,0.072779513,1.284801269,0.974166057,1.707222361,0.166175252,DB1386710013573_,1.79471231,0.250604052,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,fluticasone,DB13867
,65656,DB00338,10036790,131,33543,91,22181,0.731516433,0.951959995,0.722607496,1.258645342,0.843884548,DB0033810036790_,0.169739585,-0.049232267,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,65657,DB00471,10036790,87,14102,37,5428,0.615685795,0.905069234,0.608543527,1.369970464,0.757016036,DB0047110036790_,0.278370842,-0.099743837,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,65659,DB00904,10036790,87,22982,50,14406,0.660800803,1.090710104,0.761125675,1.577943012,0.792989993,DB0090410036790_,0.231944677,0.086828955,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,65661,DB13867,10036790,39,4511,24,2530,0.792156171,0.911397206,0.533083862,1.58823455,0.88743507,DB1386710036790_,0.119419921,-0.092776466,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,65664,DB00451,10060945,42,47229,18,15401,0.36743947,0.760885062,0.428451786,1.404731412,0.537115729,DB0045110060945_,0.621541698,-0.273272968,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,65668,DB00904,10060945,37,23032,24,14432,0.895894943,0.965995685,0.562421834,1.688670881,0.956249434,DB0090410060945_,0.044736485,-0.034595911,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,ondansetron,DB00904
,65670,DB01234,10060945,39,31586,40,32848,1,1.013956955,0.635134779,1.617496475,1,DB0123410060945_,0,0.013860453,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,65682,DB08865,10035598,35,1176,19,952,0.168922238,1.490960154,0.823650328,2.778178038,0.30939844,DB0886510035598_,1.173125384,0.399420311,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,crizotinib,DB08865
,65688,DB00476,10040108,128,17129,49,6128,0.669374621,0.934543157,0.666491354,1.328764222,0.799260087,DB0047610040108_,0.224068871,-0.067697471,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,65689,DB00924,10040108,41,10121,32,4219,0.009646136,0.534092673,0.327719288,0.877552909,0.034581647,DB0092410040108_,3.364432166,-0.627185909,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,65698,DB00586,10003549,155,6954,64,2741,0.761755343,0.954612343,0.706447071,1.302684936,0.867966655,DB0058610003549_,0.141601982,-0.046449945,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,65702,DB00586,10003658,38,7071,19,2786,0.38023597,0.788007109,0.442295665,1.449783753,0.550337744,DB0058610003658_,0.59722311,-0.238248167,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,diclofenac,DB00586
,65703,DB01104,10003658,90,15373,57,7229,0.09156023,0.742470503,0.526341981,1.054906938,0.19776167,DB0110410003658_,1.620692661,-0.297772135,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,sertraline,DB01104
,65716,DB00231,10024855,45,3251,23,2116,0.383472593,1.273391934,0.751796603,2.211933213,0.553488393,DB0023110024855_,0.591514498,0.241684154,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,temazepam,DB00231
,65717,DB00321,10024855,66,7381,31,2819,0.361791308,0.813123422,0.521808234,1.292387596,0.531535913,DB0032110024855_,0.631984514,-0.20687237,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,65719,DB00586,10024855,38,7071,22,2783,0.152103555,0.679847596,0.39116243,1.209146738,0.286865318,DB0058610024855_,1.248742448,-0.38588663,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,65720,DB01104,10024855,113,15350,63,7223,0.29203851,0.844028633,0.61393789,1.169241876,0.457517716,DB0110410024855_,0.781939672,-0.16956886,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,65727,DB00451,10036653,117,47154,31,15388,0.33959369,1.231641193,0.822551532,1.894799357,0.508660007,DB0045110036653_,0.675975449,0.208347583,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,65742,DB00207,10002855,138,8942,32,5423,1.5349769199666e-07,2.615219996,1.76666182,3.977817885,2.6808550392905e-06,DB0020710002855_,12.82937477,0.961348223,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,azithromycin,DB00207
,65743,DB00207,10012378,105,8975,29,5426,0.000101393,2.188844822,1.436923949,3.430726643,0.000807612,DB0020710012378_,7.121428428,0.783373926,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,azithromycin,DB00207
,65753,DB00051,10069868,198,25533,87,11333,1,1.010160012,0.780397375,1.316583147,1,DB0005110069868_,0,0.010108746,NA,10069868,Device issue,10077536,Product issues,Prod,adalimumab,DB00051
,65755,DB08895,10019974,603,27511,105,6541,0.003181209,1.365400758,1.106067099,1.69934263,0.014194209,DB0889510019974_,4.254921246,0.311447981,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,65764,DB01015,10040070,45,9842,63,9318,0.053066459,0.676274318,0.450247257,1.008427625,0.130760867,DB0101510040070_,2.034385066,-0.391156489,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,65765,DB00108,10028997,204,9990,63,3232,0.82912188,1.047564052,0.783786472,1.416705455,0.910222971,DB0010810028997_,0.094065686,0.046467519,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,natalizumab,DB00108
,65771,DB08932,10023232,205,19238,54,6543,0.098887262,1.291125349,0.951098504,1.77882276,0.209186888,DB0893210023232_,1.564527224,0.255514201,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,65774,DB00115,10019909,41,18384,28,10444,0.454144181,0.831879172,0.501829097,1.397663772,0.621620468,DB0011510019909_,0.475425552,-0.184068075,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,65780,DB00472,10037844,205,10554,52,4260,0.002674657,1.591245934,1.165929315,2.205679973,0.012309747,DB0047210037844_,4.397363887,0.464517316,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,fluoxetine,DB00472
,65783,DB01229,10013709,78,5663,33,2676,0.682308101,1.116896368,0.732425544,1.737428412,0.807853728,DB0122910013709_,0.213374267,0.110553738,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,paclitaxel,DB01229
,65799,DB00316,10002368,64,65410,58,36895,0.010584274,0.622381811,0.429320164,0.904019799,0.037240834,DB0031610002368_,3.290349443,-0.474201531,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,65803,DB00404,10002368,42,19850,25,9837,0.516061441,0.832570867,0.495443463,1.42632723,0.675784032,DB0040410002368_,0.391881734,-0.183236935,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,65804,DB00451,10002368,68,47203,32,15387,0.102771281,0.692701664,0.448527945,1.090409847,0.215186453,DB0045110002368_,1.536250405,-0.367155872,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,65806,DB00722,10002368,27,25376,34,25998,0.444442473,0.813587103,0.472003649,1.389635283,0.612497792,DB0072210002368_,0.490209941,-0.206302286,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,65810,DB01104,10002368,46,15417,28,7258,0.317908635,0.773461311,0.472851736,1.286137234,0.485855483,DB0110410002368_,0.721844059,-0.256879629,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,65811,DB00737,10002855,66,2735,8,924,0.003953516,2.786801249,1.328061275,6.747881204,0.016913766,DB0073710002855_,4.079627413,1.024894432,female,10002855,Anxiety,10037175,Psychiatric disorders,Psych,meclizine,DB00737
,65812,DB01039,10002855,64,2909,34,3017,0.001514779,1.952012655,1.264068473,3.062189342,0.007756861,DB0103910002855_,4.859177508,0.668860971,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,fenofibrate,DB01039
,65813,DB00316,10069326,54,65420,44,36909,0.073828049,0.692439548,0.45632711,1.055750328,0.167912977,DB0031610069326_,1.784309428,-0.36753434,NA,10069326,Product substitution issue,10077536,Product issues,Prod,acetaminophen,DB00316
,65814,DB00331,10069326,63,24883,50,20702,0.850198059,1.048295692,0.711362798,1.551916575,0.925877715,DB0033110069326_,0.07701311,0.047165695,NA,10069326,Product substitution issue,10077536,Product issues,Prod,metformin,DB00331
,65816,DB00404,10069326,44,19848,21,9841,1,1.038843272,0.604264229,1.840402121,1,DB0040410069326_,0,0.038107855,NA,10069326,Product substitution issue,10077536,Product issues,Prod,alprazolam,DB00404
,65821,DB01104,10069326,32,15431,23,7263,0.146871182,0.654857692,0.371132028,1.172847903,0.279615327,DB0110410069326_,1.274340451,-0.42333733,NA,10069326,Product substitution issue,10077536,Product issues,Prod,sertraline,DB01104
,65828,DB00682,10042364,32,19427,41,16323,0.078000604,0.655798481,0.399543676,1.067759091,0.17500285,DB0068210042364_,1.74295302,-0.421901732,NA,10042364,Subdural haemorrhage,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,65831,DB00921,10013709,412,5433,249,4654,2.24464128648779e-05,1.417324863,1.202027452,1.673722245,0.00022048,DB0092110013709_,8.419704448,0.348771195,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,65835,DB08889,10016288,24,3141,51,3834,0.026306393,0.574458772,0.337335908,0.953039015,0.076442822,DB0888910016288_,2.571212249,-0.554326948,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,carfilzomib,DB08889
,65839,DB08889,10043554,50,3115,65,3820,0.777577525,0.94332102,0.637040809,1.389745625,0.878740499,DB0888910043554_,0.129265648,-0.05834863,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,carfilzomib,DB08889
,65845,DB00761,10003119,40,15267,24,8601,0.795721447,0.938956453,0.551936034,1.629517461,0.889397596,DB0076110003119_,0.117210904,-0.062986177,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,65847,DB01234,10003119,32,31593,50,32838,0.077022869,0.665227882,0.41287386,1.057755473,0.173208378,DB0123410003119_,1.753259915,-0.407625617,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,65848,DB00421,10003658,170,8733,98,5154,0.89846637,1.023772621,0.791769544,1.329763345,0.956411402,DB0042110003658_,0.044567122,0.023494452,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,spironolactone,DB00421
,65853,DB00588,10005734,53,16471,31,8437,0.564873759,0.875764914,0.551480476,1.412594973,0.716501714,DB0058810005734_,0.33337464,-0.132657587,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,65855,DB00448,10013710,33,5112,28,3096,0.188212625,0.713833051,0.417359047,1.22871238,0.334307298,DB0044810013710_,1.095694656,-0.337106166,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,65857,DB00904,10013710,173,22896,254,14202,1.59927698441614e-18,0.422482908,0.345825907,0.515167472,1.43716224052576e-16,DB0090410013710_,36.47869098,-0.861606288,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,65860,DB00588,10015090,109,16415,54,8414,0.868499546,1.03465199,0.739218343,1.463229084,0.941381879,DB0058810015090_,0.060406399,0.034065129,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,65861,DB00904,10015090,169,22900,114,14342,0.540426934,0.928447401,0.727112567,1.189112403,0.695972984,DB0090410015090_,0.362444435,-0.074241549,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,65862,DB01409,10015090,51,5980,22,3944,0.117912336,1.528851786,0.909012537,2.651864368,0.238043453,DB0140910015090_,1.435302046,0.424516987,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,65863,DB00515,10018884,48,1822,33,2118,0.023972326,1.690608127,1.057905921,2.731566838,0.071191119,DB0051510018884_,2.642387196,0.525088303,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,cisplatin,DB00515
,65867,DB01076,10037377,140,25607,210,25373,0.000135662,0.660583634,0.529141752,0.822575206,0.001034339,DB0107610037377_,6.873992226,-0.414631541,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,65873,DB08880,10000081,43,3295,9,800,0.860153616,1.159966161,0.554802689,2.717674896,0.934091433,DB0888010000081_,0.068180952,0.148390833,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,teriflunomide,DB08880
,65874,DB08880,10028813,219,3119,30,779,0.001658465,1.822954602,1.229519455,2.789703308,0.00833992,DB0888010028813_,4.786701611,0.600458593,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,teriflunomide,DB08880
,65876,DB00575,10048294,87,5157,47,3782,0.094783253,1.357472895,0.938844368,1.984195292,0.20292169,DB0057510048294_,1.59493514,0.305624806,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,clonidine,DB00575
,65883,DB00563,10042945,90,46556,9,15339,0.000101048,3.294807451,1.659968694,7.44047839,0.000805108,DB0056310042945_,7.124534463,1.192347729,female,10042945,Systemic lupus erythematosus,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,65887,DB00005,10061246,117,127965,30,42389,0.251642192,1.291879799,0.858693863,1.999774525,0.411638688,DB0000510061246_,0.887609285,0.256098366,NA,10061246,Intervertebral disc degeneration,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,65888,DB00563,10061246,63,46583,14,15334,0.233490775,1.481249725,0.820685795,2.863756444,0.390128405,DB0056310061246_,0.94127935,0.39288614,NA,10061246,Intervertebral disc degeneration,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,65893,DB01075,10022000,192,19756,109,10988,0.856380901,0.9796927,0.769554621,1.252519288,0.930914248,DB0107510022000_,0.071588113,-0.020516328,NA,10022000,Influenza,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,65895,DB00005,10030973,42,128040,8,42411,0.189512992,1.738891558,0.806444127,4.288750848,0.335934466,DB0000510030973_,1.090839179,0.553247875,NA,10030973,Oral discomfort,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,65897,DB01109,10069327,35,4377,53,4217,0.041526482,0.636274645,0.402015896,0.99579537,0.108807331,DB0110910069327_,2.218176564,-0.452124977,NA,10069327,Product quality issue,10077536,Product issues,Prod,heparin,DB01109
,65900,DB00338,10061520,78,33596,35,22237,0.054943218,1.475067969,0.977655744,2.266143566,0.134230178,DB0033810061520_,2.008199203,0.38870407,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,65906,DB01075,10061520,55,19893,18,11079,0.050495462,1.701701722,0.98344095,3.08111267,0.125915303,DB0107510061520_,2.072145796,0.531628764,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,65907,DB00563,10019303,83,46563,25,15323,0.823370997,1.092546908,0.691130946,1.784498981,0.906247631,DB0056310019303_,0.098442687,0.088511584,NA,10019303,Heart rate increased,10022891,Investigations,Inv,methotrexate,DB00563
,65912,DB01275,10061818,27,3952,33,3316,0.154063749,0.686553295,0.396175063,1.180132548,0.289623489,DB0127510061818_,1.239173512,-0.376071423,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,65922,DB06643,10041541,99,52322,10,7505,0.383387388,1.420035194,0.740163687,3.054442734,0.55342619,DB0664310041541_,0.591626887,0.350681656,NA,10041541,Spinal compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,65952,DB00415,10013709,47,739,51,491,0.024485546,0.612552498,0.396245947,0.945162957,0.072363682,DB0041510013709_,2.62605074,-0.490120629,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ampicillin,DB00415
,65955,DB00921,10025482,136,5709,90,4813,0.079525699,1.273919595,0.966085215,1.686545875,0.177636117,DB0092110025482_,1.728018107,0.242098443,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,65956,DB00921,10069326,90,5755,109,4794,0.009626033,0.687841833,0.513033739,0.920339954,0.034527877,DB0092110069326_,3.365988254,-0.374196362,NA,10069326,Product substitution issue,10077536,Product issues,Prod,buprenorphine,DB00921
,65959,DB08934,10013781,16,4473,36,6168,0.120935929,0.612890462,0.317126262,1.134613208,0.242804834,DB0893410013781_,1.415497311,-0.489569051,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,sofosbuvir,DB08934
,65970,DB00316,10031127,59,65415,65,36888,0.000233725,0.511843644,0.353538304,0.73976358,0.001640446,DB0031610031127_,6.412787255,-0.669736082,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,65974,DB00243,10019211,39,1215,37,1589,0.196905495,1.378339545,0.850502618,2.237339455,0.345260892,DB0024310019211_,1.06345494,0.320879546,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ranolazine,DB00243
,65983,DB00338,10022067,51,33623,18,22254,0.0194261,1.875269018,1.076833036,3.412009552,0.060420665,DB0033810022067_,2.806424097,0.628752125,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,65984,DB00451,10022067,84,47187,20,15399,0.25382329,1.370602463,0.833591959,2.357982922,0.414355505,DB0045110022067_,0.881030965,0.315250397,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,65986,DB08895,10030124,127,27987,38,6608,0.197729594,0.789109244,0.544758614,1.166960771,0.346234253,DB0889510030124_,1.060639701,-0.236850509,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,65989,DB00795,10033425,111,4458,27,1476,0.163371019,1.361060889,0.883029665,2.165942476,0.301898709,DB0079510033425_,1.19766372,0.308264461,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfasalazine,DB00795
,65990,DB00795,10052904,104,4465,26,1477,0.218999876,1.323105335,0.850190653,2.128161534,0.372342286,DB0079510052904_,0.987941725,0.2799815,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfasalazine,DB00795
,65991,DB00188,10008479,53,7833,74,8754,0.246083705,0.800440156,0.550888916,1.156083956,0.405016134,DB0018810008479_,0.903828375,-0.222593507,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,65992,DB00215,10008479,131,10972,53,5223,0.341759226,1.176576963,0.847406361,1.653892003,0.510986419,DB0021510008479_,0.671412266,0.162609344,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,65994,DB01039,10008479,43,2930,45,3006,1,0.980341766,0.628081519,1.528347904,1,DB0103910008479_,0,-0.019854027,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,65998,DB00480,10050819,89,67339,79,67583,0.440889158,1.130662749,0.825531901,1.550992267,0.609149861,DB0048010050819_,0.495690965,0.122803964,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,66001,DB00996,10029216,138,38815,50,22375,0.004868742,1.590996693,1.142936162,2.246189466,0.020030501,DB0099610029216_,3.910499103,0.464360671,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,66003,DB00678,10017413,103,15496,52,10672,0.071391088,1.364127136,0.96721224,1.944334787,0.16368047,DB0067810017413_,1.809839103,0.310514763,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,losartan,DB00678
,66004,DB01234,10017413,435,31190,375,32513,0.00795426,1.209198436,1.049835353,1.393276244,0.029654312,DB0123410017413_,3.518147733,0.18995769,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,66009,DB00619,10000087,43,2856,34,2460,0.731328115,1.089365128,0.676203758,1.76741852,0.843741364,DB0061910000087_,0.169909272,0.085595075,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,imatinib,DB00619
,66010,DB14512,10000087,53,4791,14,2398,0.036285307,1.894684914,1.033776066,3.705499053,0.098098154,DB1451210000087_,2.321786731,0.639052552,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,mometasone furoate,DB14512
,66016,DB00619,10030095,39,2860,18,2476,0.03181471,1.875543727,1.044547663,3.492444435,0.088689113,DB0061910030095_,2.422618135,0.628898605,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,66021,DB00668,10003553,142,9949,28,4275,6.62971039723378e-05,2.179050605,1.442539559,3.400806789,0.000560238,DB0066810003553_,7.487149393,0.77888928,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,66022,DB01075,10003553,146,19802,20,11077,5.38870615004756e-12,4.083389461,2.547529284,6.886234807,2.16058553759619e-10,DB0107510003553_,22.25547166,1.406927394,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,66023,DB01175,10003553,47,10677,11,4881,0.046477248,1.953208381,0.997386189,4.179849425,0.118459596,DB0117510003553_,2.133183342,0.669473344,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,66026,DB00169,10009033,201,38490,90,18085,0.752775513,1.04935789,0.813869973,1.361880278,0.860759297,DB0016910009033_,0.149940375,0.048178444,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,66027,DB01175,10009033,71,10653,28,4864,0.587051122,1.157749936,0.736874472,1.865190304,0.734197971,DB0117510009033_,0.308976572,0.146478411,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,66028,DB01592,10009033,36,6240,20,3047,0.669301564,0.878961008,0.494405265,1.605302871,0.799227313,DB0159210009033_,0.224109877,-0.129014742,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iron,DB01592
,66032,DB00091,10066901,25,5485,32,2638,0.000302947,0.375789144,0.213020162,0.655972719,0.00203344,DB0009110066901_,6.198026326,-0.978727081,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,66034,DB00959,10066901,41,8037,40,4962,0.050483379,0.632875908,0.398653501,1.005383409,0.125897118,DB0095910066901_,2.072290226,-0.457480914,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,66043,DB00959,10008190,43,8035,22,4980,0.523396364,1.211350766,0.707818311,2.129257247,0.681683327,DB0095910008190_,0.383190059,0.191736072,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,66044,DB04868,10008190,47,1594,39,1477,0.662228308,1.116625656,0.710238842,1.764311521,0.79404641,DB0486810008190_,0.230613368,0.11031133,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,nilotinib,DB04868
,66045,DB14500,10008190,68,7741,70,4003,6.50937295309268e-05,0.502358626,0.35363421,0.713338769,0.000551398,DB1450010008190_,7.503053285,-0.688441019,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,potassium,DB14500
,66050,DB00820,10065154,76,11839,36,5780,0.919920442,1.030646415,0.683688519,1.579943218,0.964555064,DB0082010065154_,0.036088358,0.030186193,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,tadalafil,DB00820
,66052,DB01075,10021143,100,19848,93,11004,0.000382098,0.596125867,0.444523338,0.800168465,0.00246798,DB0107510021143_,6.004355343,-0.517303448,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,66053,DB01075,10028411,161,19787,70,11027,0.085249062,1.281769531,0.961322422,1.723895435,0.187152058,DB0107510028411_,1.67583385,0.24824157,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,66072,DB00108,10041466,56,10138,21,3274,0.594520807,0.861216195,0.512331894,1.49980842,0.740404597,DB0010810041466_,0.30055849,-0.149409708,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,66073,DB00108,10047571,84,10110,27,3268,1,1.005649035,0.643746629,1.617394462,1,DB0010810047571_,0,0.005633139,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,natalizumab,DB00108
,66074,DB00338,10042458,153,33521,100,22172,0.948756918,1.011997394,0.78096356,1.316252661,0.987138328,DB0033810042458_,0.012945099,0.011925996,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,66075,DB00404,10042458,198,19694,70,9792,0.013279413,1.406371057,1.064488747,1.876527206,0.044618353,DB0040410042458_,3.109609999,0.341012669,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,66090,DB00178,10013709,53,1384,65,1615,0.850800795,0.951481777,0.644438034,1.399614002,0.926372712,DB0017810013709_,0.076478629,-0.049734744,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ramipril,DB00178
,66110,DB00480,10000891,34,67394,84,67578,4.69840715448936e-06,0.405846076,0.264106775,0.611357561,5.60206995036302e-05,DB0048010000891_,9.789789302,-0.901781313,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,66111,DB00641,10000891,37,14087,60,12415,0.00408488,0.543491941,0.350445733,0.832883953,0.017376773,DB0064110000891_,4.052620875,-0.609740401,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,simvastatin,DB00641
,66113,DB01050,10050584,133,17975,23,9348,6.13511488861653e-08,3.007177288,1.920139145,4.910503282,1.16308326611818e-06,DB0105010050584_,13.66443609,1.101001861,female,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,66115,DB00230,10000059,203,19471,68,8583,0.054449252,1.315889094,0.994020902,1.760519268,0.133351836,DB0023010000059_,2.014764261,0.274512554,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,66116,DB00230,10029202,42,19632,13,8638,0.30668402,1.421552454,0.748078057,2.887786728,0.473741742,DB0023010029202_,0.747092955,0.351749552,NA,10029202,Nervous system disorder,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,66117,DB00230,10046543,67,19607,18,8633,0.075988,1.638875859,0.961786928,2.932886378,0.171453245,DB0023010046543_,1.763444671,0.494010555,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,pregabalin,DB00230
,66118,DB00230,10047899,868,18806,187,8464,5.14103509461291e-22,2.089043477,1.777795508,2.464968926,6.57577165264722e-20,DB0023010047899_,44.16830993,0.736706295,NA,10047899,Weight increased,10022891,Investigations,Inv,pregabalin,DB00230
,66150,DB00047,10003239,142,9143,90,8428,0.005444479,1.454357312,1.1070593,1.918914638,0.021896079,DB0004710003239_,3.821447718,0.374564093,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin glargine,DB00047
,66151,DB00230,10003239,645,19029,161,8490,8.86232687298881e-12,1.787382847,1.498620251,2.141832675,3.41563433807201e-10,DB0023010003239_,21.7974877,0.580752453,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,66152,DB00624,10003239,12,550,81,4315,0.619536816,1.162239912,0.573020923,2.160433812,0.760266356,DB0062410003239_,0.274086438,0.150349102,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,testosterone,DB00624
,66153,DB00697,10003239,224,5872,36,1770,0.000291855,1.87534187,1.308675452,2.757585121,0.001973084,DB0069710003239_,6.228157231,0.628790974,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tizanidine,DB00697
,66157,DB01306,10003239,74,4134,68,3798,1,0.999816151,0.707288667,1.415091391,1,DB0130610003239_,0,-0.000183866,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin aspart,DB01306
,66159,DB00273,10010774,129,8352,24,2169,0.157678527,1.395828584,0.895135236,2.263475066,0.294366539,DB0027310010774_,1.222929557,0.333488206,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,topiramate,DB00273
,66160,DB00555,10010774,93,6954,44,3442,0.855277694,1.046175261,0.721556581,1.537243872,0.92990731,DB0055510010774_,0.072670364,0.045140905,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,lamotrigine,DB00555
,66161,DB00557,10010774,104,5883,40,3027,0.131373287,1.337760316,0.917966892,1.983163509,0.257707142,DB0055710010774_,1.355931449,0.29099681,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,hydroxyzine,DB00557
,66162,DB00624,10010774,10,552,48,4348,0.147029925,1.640797485,0.735831085,3.308415964,0.279816209,DB0062410010774_,1.273622287,0.495182395,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,testosterone,DB00624
,66164,DB01046,10010774,44,841,15,313,0.880916474,1.091637315,0.585910763,2.143162007,0.950123172,DB0104610010774_,0.051163648,0.087678693,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,lubiprostone,DB01046
,66166,DB01261,10010774,92,3689,90,3213,0.452297847,0.890337996,0.655840892,1.208990341,0.619926941,DB0126110010774_,0.478153645,-0.116154117,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sitagliptin,DB01261
,66168,DB13961,10010774,219,9238,182,6232,0.044307876,0.811767488,0.661993909,0.996324744,0.114224452,DB1396110010774_,2.169589891,-0.208541325,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,66169,DB00273,10013709,619,7862,232,1961,1.0643556189863e-06,0.665527098,0.566649378,0.783558476,1.51183936476924e-05,DB0027310013709_,11.09959843,-0.407175924,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,66170,DB01046,10013709,35,850,15,313,0.627502254,0.859343927,0.449963688,1.71810715,0.766909446,DB0104610013709_,0.265386548,-0.151586057,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lubiprostone,DB01046
,66171,DB01132,10013709,64,1221,47,1483,0.01124439,1.653572088,1.107985803,2.48310303,0.03910025,DB0113210013709_,3.241626418,0.50293785,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pioglitazone,DB01132
,66172,DB13961,10013709,453,9004,252,6162,0.009576276,1.230206813,1.048530818,1.445827796,0.034402159,DB1396110013709_,3.369635963,0.207182296,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,66173,DB00230,10013911,38,19636,17,8634,1,0.982864881,0.541137866,1.858108689,1,DB0023010013911_,0,-0.017283624,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,66175,DB00281,10013911,33,11425,18,5653,0.766345068,0.907127173,0.495641993,1.712765393,0.871347685,DB0028110013911_,0.137714203,-0.097472626,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,66176,DB00295,10013911,27,14636,34,9568,0.012264399,0.519142234,0.301073797,0.887087419,0.041879796,DB0029510013911_,3.172951755,-0.655577379,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,morphine,DB00295
,66177,DB00425,10013911,58,12637,34,7450,1,1.005683365,0.646879899,1.585683595,1,DB0042510013911_,0,0.005667275,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,66178,DB00497,10013911,77,19190,70,16305,0.679593432,0.934648204,0.666864138,1.311811293,0.806188124,DB0049710013911_,0.215438159,-0.067585073,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,66185,DB01050,10013911,95,18013,42,9329,0.417388737,1.171425869,0.80579065,1.728633077,0.586515354,DB0105010013911_,0.533556433,0.158221698,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,66187,DB01175,10013911,48,10676,19,4873,0.692579497,1.153104535,0.664453953,2.079621859,0.814826761,DB0117510013911_,0.204779751,0.1424579,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,66224,DB00451,10018484,57,47214,26,15393,0.160949068,0.714754077,0.441947467,1.184779036,0.298756842,DB0045110018484_,1.208125273,-0.335816744,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,levothyroxine,DB00451
,66232,DB00996,10018484,36,38917,21,22404,1,0.986887428,0.560602888,1.779619221,1,DB0099610018484_,0,-0.0131993,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,gabapentin,DB00996
,66234,DB01076,10018484,59,25688,50,25533,0.443438609,1.172875141,0.790670089,1.745883468,0.611575753,DB0107610018484_,0.491716451,0.15945812,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,atorvastatin,DB01076
,66238,DB01261,10018484,45,3736,41,3262,0.913496983,0.958297946,0.611876892,1.504635661,0.961296669,DB0126110018484_,0.039472209,-0.042596541,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,sitagliptin,DB01261
,66239,DB01276,10018484,38,1979,32,1479,0.627625483,0.887506392,0.537090461,1.475021125,0.767023239,DB0127610018484_,0.265238179,-0.119339555,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,exenatide,DB01276
,66240,DB01306,10018484,41,4167,33,3833,0.640464025,1.142820108,0.703385823,1.869616689,0.777426154,DB0130610018484_,0.251766618,0.133498987,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,insulin aspart,DB01306
,66243,DB00230,10023232,240,19434,71,8580,0.002898922,1.492370332,1.139232983,1.975798325,0.013139208,DB0023010023232_,4.33215452,0.400365682,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,66245,DB00281,10023232,61,11397,18,5653,0.054997357,1.68086866,0.979136424,3.025295945,0.134331229,DB0028110023232_,2.007446668,0.519310719,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,lidocaine,DB00281
,66246,DB00295,10023232,58,14605,29,9573,0.272145723,1.310906216,0.824988617,2.125326108,0.435052476,DB0029510023232_,0.832288621,0.270718666,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,66247,DB00497,10023232,107,19160,60,16315,0.010060627,1.518511204,1.096022296,2.12093113,0.035738033,DB0049710023232_,3.331539814,0.417730384,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,66251,DB00697,10023232,65,6031,8,1798,0.01629398,2.422157202,1.156222906,5.857636703,0.052579617,DB0069710023232_,2.94542674,0.884658549,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,tizanidine,DB00697
,66254,DB01076,10023232,231,25516,154,25429,0.000119121,1.494866111,1.212964408,1.846532168,0.000925675,DB0107610023232_,6.98498739,0.402036645,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,66256,DB01156,10023232,60,13562,18,6310,0.113054656,1.55087073,0.902360326,2.793648456,0.230636938,DB0115610023232_,1.466910502,0.438816534,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,66267,DB00555,10027940,42,7005,8,3478,0.009791777,2.606440962,1.207155698,6.434616043,0.034995833,DB0055510027940_,3.352526293,0.957985675,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,66273,DB00996,10027940,65,38888,40,22385,0.761295833,0.93539635,0.62110908,1.424210639,0.867650712,DB0099610027940_,0.141966051,-0.066784936,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,66281,DB00273,10028372,73,8408,27,2166,0.134359697,0.696532604,0.441114398,1.12989254,0.261777824,DB0027310028372_,1.340259133,-0.361640676,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,topiramate,DB00273
,66282,DB00281,10028372,86,11372,41,5630,0.924651703,1.038436065,0.70683518,1.547621189,0.967584075,DB0028110028372_,0.032952959,0.037715798,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,lidocaine,DB00281
,66283,DB00555,10028372,48,6999,24,3462,1,0.989281445,0.593006394,1.69152613,1,DB0055510028372_,0,-0.010776412,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,lamotrigine,DB00555
,66284,DB00557,10028372,55,5932,21,3046,0.274781262,1.344819414,0.798475662,2.345756128,0.438000331,DB0055710028372_,0.825535612,0.296259739,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxyzine,DB00557
,66286,DB00697,10028372,92,6004,29,1777,0.744277368,0.938938271,0.610298817,1.483971298,0.853959003,DB0069710028372_,0.157872093,-0.063005541,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,tizanidine,DB00697
,66290,DB01156,10028372,93,13529,29,6299,0.063538987,1.493079005,0.973663342,2.352839896,0.149847228,DB0115610028372_,1.898138984,0.400840434,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,66291,DB01175,10028372,98,10626,40,4852,0.581452203,1.118696885,0.765725835,1.661738927,0.729765132,DB0117510028372_,0.315032534,0.112164512,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,66296,DB00047,10028391,32,9253,20,8498,0.2108084,1.469411536,0.814299905,2.713169328,0.362221334,DB0004710028391_,1.015499834,0.384862005,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin glargine,DB00047
,66298,DB00295,10028391,66,14597,27,9575,0.043038349,1.60341853,1.009596394,2.612557179,0.111762404,DB0029510028391_,2.191380049,0.472137931,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,66299,DB00497,10028391,84,19183,63,16312,0.457114452,1.133765091,0.807538218,1.598844113,0.624412284,DB0049710028391_,0.470944417,0.125544033,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,66302,DB00697,10028391,43,6053,12,1794,1,1.062002734,0.548713847,2.217389556,1,DB0069710028391_,0,0.060156497,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tizanidine,DB00697
,66303,DB00904,10028391,129,22940,52,14404,0.007204538,1.557653761,1.119778071,2.19436419,0.027391523,DB0090410028391_,3.597521697,0.44318069,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,66306,DB01076,10028391,161,25586,109,25474,0.001832996,1.470580277,1.145344023,1.894086493,0.009056447,DB0107610028391_,4.704278409,0.385657069,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,66311,DB13961,10028391,83,9374,31,6383,0.003904656,1.823054807,1.191912766,2.853890118,0.016734696,DB1396110028391_,4.090271113,0.600513559,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,66312,DB01046,10028813,59,826,14,314,0.13528493,1.60147967,0.868052483,3.152179348,0.263086743,DB0104610028813_,1.335271482,0.470927996,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lubiprostone,DB01046
,66313,DB01132,10028813,70,1215,80,1450,0.801103949,1.044244709,0.739599546,1.4714609,0.892412152,DB0113210028813_,0.113827199,0.043293858,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pioglitazone,DB01132
,66314,DB01261,10028813,220,3561,142,3161,0.004103567,1.375201539,1.102254054,1.719957209,0.017442152,DB0126110028813_,4.048865454,0.318600294,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sitagliptin,DB01261
,66315,DB06204,10028813,40,772,14,365,0.373507705,1.350544284,0.708556411,2.722968934,0.543267024,DB0620410028813_,0.610154323,0.300507685,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,tapentadol,DB06204
,66316,DB00557,10047895,111,5876,57,3010,1,0.997545854,0.716118225,1.402536514,1,DB0055710047895_,0,-0.002457163,NA,10047895,Weight decreased,10022891,Investigations,Inv,hydroxyzine,DB00557
,66317,DB00624,10047895,8,554,93,4303,0.341318212,0.66818898,0.27868367,1.382082412,0.510472216,DB0062410047895_,0.672419069,-0.403184242,NA,10047895,Weight decreased,10022891,Investigations,Inv,testosterone,DB00624
,66320,DB01132,10047895,34,1251,33,1497,0.456705416,1.232807459,0.736132697,2.066698308,0.624096795,DB0113210047895_,0.471449803,0.209294056,NA,10047895,Weight decreased,10022891,Investigations,Inv,pioglitazone,DB01132
,66322,DB00295,10047899,121,14542,61,9541,0.094786856,1.301429185,0.947854768,1.802934419,0.20292169,DB0029510047899_,1.59493514,0.263463033,NA,10047899,Weight increased,10022891,Investigations,Inv,morphine,DB00295
,66323,DB00555,10047899,129,6918,63,3423,1,1.01315302,0.741721593,1.396063811,1,DB0055510047899_,0,0.01306727,NA,10047899,Weight increased,10022891,Investigations,Inv,lamotrigine,DB00555
,66324,DB00557,10047899,136,5851,34,3033,7.68643502856119e-05,2.073344942,1.410873156,3.123022746,0.000636039,DB0055710047899_,7.360249902,0.729163217,NA,10047899,Weight increased,10022891,Investigations,Inv,hydroxyzine,DB00557
,66325,DB00624,10047899,8,554,57,4339,0.84296967,1.09918868,0.450469373,2.331684759,0.920274859,DB0062410047899_,0.083082894,0.094572344,NA,10047899,Weight increased,10022891,Investigations,Inv,testosterone,DB00624
,66326,DB00697,10047899,107,5989,20,1786,0.055300052,1.59531858,0.979940753,2.724224023,0.134876298,DB0069710047899_,2.003397234,0.467073453,NA,10047899,Weight increased,10022891,Investigations,Inv,tizanidine,DB00697
,66327,DB00904,10047899,296,22773,108,14348,7.09458577217861e-07,1.726762317,1.37929971,2.175130998,1.05685002562604e-05,DB0090410047899_,11.45763265,0.546248162,NA,10047899,Weight increased,10022891,Investigations,Inv,ondansetron,DB00904
,66330,DB01132,10047899,36,1249,22,1508,0.015789016,1.975188367,1.124222122,3.544374034,0.051321867,DB0113210047899_,2.96963837,0.68066377,NA,10047899,Weight increased,10022891,Investigations,Inv,pioglitazone,DB01132
,66333,DB13961,10047899,172,9285,77,6337,0.002162647,1.524502176,1.156264069,2.025399648,0.010376047,DB1396110047899_,4.568255272,0.421667915,NA,10047899,Weight increased,10022891,Investigations,Inv,fish oil,DB13961
,66342,DB00996,10049119,57,38896,21,22404,0.078844222,1.563410629,0.9329569,2.715924787,0.176398722,DB0099610049119_,1.73500838,0.446869736,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,66379,DB00230,10062519,50,19624,19,8632,0.694831135,1.157538338,0.670013857,2.080360812,0.816298847,DB0023010062519_,0.202974756,0.146295627,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,66383,DB00316,10062519,92,65382,51,36902,1,1.01814465,0.715276794,1.463490207,1,DB0031610062519_,0,0.017982,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,66384,DB00331,10062519,32,24914,24,20728,0.788648806,1.109275411,0.632957217,1.968836159,0.885541196,DB0033110062519_,0.1215563,0.10370702,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,metformin,DB00331
,66385,DB00425,10062519,32,12663,28,7456,0.140796219,0.67295604,0.39213568,1.160985285,0.270964168,DB0042510062519_,1.305768688,-0.396075271,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,66386,DB00451,10062519,83,47188,41,15378,0.036174907,0.659729502,0.448376915,0.984395694,0.097890299,DB0045110062519_,2.323907823,-0.415925374,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,66387,DB00497,10062519,33,19234,22,16353,0.418008281,1.275309622,0.721227952,2.297045863,0.587040721,DB0049710062519_,0.53266109,0.24318899,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,66393,DB00996,10062519,60,38893,34,22391,1,1.015954921,0.656065199,1.596642704,1,DB0099610062519_,0,0.015828979,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,66396,DB01076,10062519,43,25704,30,25553,0.159570349,1.424897103,0.873089532,2.353222454,0.296868502,DB0107610062519_,1.214465992,0.354099603,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,66410,DB00316,10062556,44,65430,11,36942,0.011516791,2.258394516,1.147509644,4.85005218,0.039862899,DB0031610062556_,3.222309234,0.81465417,NA,10062556,Grip strength decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,66497,DB00153,10000059,109,7314,39,3400,0.181987319,1.299150701,0.891419385,1.928697523,0.32635684,DB0015310000059_,1.119763895,0.261710744,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,66499,DB00343,10000059,136,8600,55,5040,0.023189993,1.449096045,1.049825395,2.024009722,0.069326772,DB0034310000059_,2.668924129,0.370939945,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,66501,DB00421,10000059,148,8755,42,5210,9.97073774809893e-06,2.096877023,1.47670762,3.03425744,0.000108298,DB0042110000059_,9.130625086,0.740449106,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,66503,DB00669,10000059,54,6323,6,1091,0.363503882,1.552820714,0.666605503,4.428158697,0.533067369,DB0066910000059_,0.629107467,0.440073092,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,sumatriptan,DB00669
,66505,DB00924,10000059,125,10037,26,4225,0.000613354,2.023677891,1.315882612,3.222981803,0.003666176,DB0092410000059_,5.608606229,0.704916594,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,66506,DB00956,10000059,76,5738,54,3413,0.317030646,0.837158826,0.581274136,1.212851497,0.484839534,DB0095610000059_,0.723937301,-0.17774147,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,hydrocodone,DB00956
,66507,DB01097,10000059,149,6116,20,1483,0.010388682,1.806320445,1.123935574,3.053541543,0.036697555,DB0109710000059_,3.305045151,0.591291873,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,leflunomide,DB01097
,66509,DB06637,10000059,73,6089,16,2003,0.173128271,1.500744877,0.862724884,2.769422119,0.314998335,DB0663710000059_,1.155187925,0.405961569,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,dalfampridine,DB06637
,66512,DB14512,10000059,45,4799,18,2394,0.502511107,1.247060365,0.705860588,2.294211706,0.663704176,DB1451210000059_,0.409918746,0.220789074,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,mometasone furoate,DB14512
,66513,DB00153,10001760,97,7326,12,3427,6.84766933942638e-07,3.780594738,2.06508107,7.580299763,1.0250056297655e-05,DB0015310001760_,11.48822736,1.329881335,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,ergocalciferol,DB00153
,66515,DB00343,10001760,85,8651,8,5087,7.47255925193441e-10,6.24808182,3.027240586,14.94814809,2.12686756834971e-08,DB0034310001760_,17.66603047,1.832274508,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,diltiazem,DB00343
,66517,DB00421,10001760,101,8802,10,5242,1.65624845661156e-11,6.015482435,3.135667822,12.93377083,6.08023612877582e-10,DB0042110001760_,21.2208074,1.794336552,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,spironolactone,DB00421
,66519,DB00635,10001760,454,32599,77,23717,1.44059362556281e-42,4.289516962,3.360808917,5.539473766,6.25884354511047e-40,DB0063510001760_,90.26940829,1.45617413,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,66521,DB00820,10001760,52,11863,10,5806,0.0041762,2.544875045,1.278283845,5.62037464,0.01768795,DB0082010001760_,4.034871672,0.93408155,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,tadalafil,DB00820
,66522,DB00924,10001760,115,10047,8,4243,4.10982264944609e-10,6.070513968,2.975823788,14.40775834,1.22271294103781e-08,DB0092410001760_,18.21960863,1.803443275,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,cyclobenzaprine,DB00924
,66523,DB00956,10001760,88,5726,9,3458,4.66698277742056e-10,5.903111521,2.967474263,13.3540862,1.37678610891694e-08,DB0095610001760_,18.10092887,1.775479588,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocodone,DB00956
,66524,DB01097,10001760,241,6024,10,1493,7.58199156034544e-13,5.972233854,3.181008404,12.6453607,3.45095494655723e-11,DB0109710001760_,24.08978503,1.787121037,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,leflunomide,DB01097
,66526,DB01592,10001760,86,6190,9,3058,1.23535160258439e-07,4.72068243,2.369771633,10.68621836,2.20592505937029e-06,DB0159210001760_,13.02436361,1.551953372,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,iron,DB01592
,66527,DB06228,10001760,173,15739,26,16050,2.15992289320786e-28,6.784883699,4.473014564,10.68940262,4.28479798097876e-26,DB0622810001760_,58.41213901,1.914697152,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,rivaroxaban,DB06228
,66531,DB00230,10003658,90,19584,45,8606,0.512077142,0.878893172,0.607334943,1.287794023,0.672340068,DB0023010003658_,0.396991013,-0.129091922,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,pregabalin,DB00230
,66534,DB00476,10003658,88,17169,41,6136,0.161524857,0.767086649,0.523143358,1.141391298,0.299497805,DB0047610003658_,1.205648192,-0.265155513,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,duloxetine,DB00476
,66535,DB00635,10003658,238,32815,306,23488,1.30404523764145e-11,0.556729271,0.467583256,0.662212432,4.87232822621259e-10,DB0063510003658_,21.44227903,-0.585676206,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,prednisone,DB00635
,66536,DB00656,10003658,56,11957,44,6575,0.093084369,0.699899512,0.462578028,1.064782753,0.200239189,DB0065610003658_,1.608242683,-0.356818509,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,trazodone,DB00656
,66539,DB00956,10003658,35,5779,27,3440,0.356547201,0.771668706,0.452914757,1.328044241,0.526242168,DB0095610003658_,0.641993776,-0.259199959,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,hydrocodone,DB00956
,66540,DB01068,10003658,50,13713,69,6771,3.86215253823792e-08,0.357819728,0.243237621,0.523124371,7.6270983822377e-07,DB0106810003658_,14.08638817,-1.027725974,male,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,clonazepam,DB01068
,66542,DB01592,10003658,82,6194,51,3016,0.192639417,0.782941314,0.543754711,1.136544017,0.33995979,DB0159210003658_,1.078927933,-0.244697535,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,iron,DB01592
,66556,DB00451,10008589,43,47228,9,15410,0.261255708,1.558886198,0.749352673,3.63792309,0.422799304,DB0045110008589_,0.860857671,0.443971591,NA,10008589,Choking,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,66605,DB00005,10010254,72,128010,12,42407,0.022930289,1.987551579,1.070839776,4.025065384,0.068744456,DB0000510010254_,2.677359189,0.686903519,NA,10010254,Concussion,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,66615,DB00451,10010254,56,47215,7,15412,0.012060958,2.611459731,1.187079789,6.79305746,0.041305833,DB0045110010254_,3.186751554,0.959909349,NA,10010254,Concussion,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,66635,DB00153,10010774,193,7230,97,3342,0.522385342,0.919725534,0.714336122,1.190500808,0.680961055,DB0015310010774_,0.384250162,-0.083679986,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,66636,DB00341,10010774,216,11189,92,4976,0.755700051,1.044119766,0.812360512,1.350819584,0.862950453,DB0034110010774_,0.147398002,0.043174201,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,66637,DB00413,10010774,47,2152,34,1173,0.239620995,0.753572252,0.471505676,1.215546002,0.39745301,DB0041310010774_,0.922678567,-0.282930377,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,pramipexole,DB00413
,66638,DB00476,10010774,279,16978,83,6094,0.148926642,1.206523767,0.93933562,1.56363117,0.282500391,DB0047610010774_,1.264075343,0.187743305,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,66639,DB00586,10010774,126,6983,41,2764,0.299339799,1.216381799,0.846353618,1.780393362,0.465364283,DB0058610010774_,0.764934775,0.195880713,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,diclofenac,DB00586
,66640,DB00656,10010774,187,11826,100,6519,0.85215595,1.030824113,0.802700209,1.330240018,0.927472274,DB0065610010774_,0.075292378,0.030358592,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,66641,DB00669,10010774,101,6276,16,1081,0.895155963,1.087300133,0.634988366,1.982476169,0.956064085,DB0066910010774_,0.044930333,0.083697682,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sumatriptan,DB00669
,66643,DB00820,10010774,195,11720,94,5722,0.949698389,1.012807152,0.786175501,1.312431692,0.988020113,DB0082010010774_,0.012052224,0.012725834,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,66644,DB00924,10010774,203,9959,75,4176,0.388011352,1.134942962,0.864456979,1.503369565,0.558047624,DB0092410010774_,0.583310973,0.126582396,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,66646,DB01592,10010774,137,6139,81,2986,0.188789178,0.822707449,0.618260032,1.100591288,0.335031802,DB0159210010774_,1.093529821,-0.195154611,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,66647,DB06637,10010774,82,6080,36,1983,0.161322749,0.742929288,0.494522888,1.135919035,0.299239156,DB0663710010774_,1.206512171,-0.29715441,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,dalfampridine,DB06637
,66650,DB00230,10011224,298,19376,89,8562,0.001021576,1.479573175,1.162247535,1.899164608,0.005602946,DB0023010011224_,5.184462679,0.391753651,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,66651,DB00318,10011224,68,4215,22,1817,0.296913128,1.332320454,0.810431966,2.270848266,0.462754911,DB0031810011224_,0.770557715,0.286922125,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,codeine,DB00318
,66652,DB00413,10011224,43,2156,18,1189,0.348368196,1.31733337,0.740013228,2.438173927,0.517963107,DB0041310011224_,0.657851261,0.275609519,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pramipexole,DB00413
,66653,DB00584,10011224,45,2036,34,1840,0.495036505,1.196062056,0.745607769,1.934612447,0.657439093,DB0058410011224_,0.419403153,0.17903454,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enalapril,DB00584
,66654,DB00669,10011224,61,6316,8,1089,0.607579377,1.314652036,0.624450198,3.190389904,0.750474309,DB0066910011224_,0.28704986,0.273572019,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sumatriptan,DB00669
,66656,DB01068,10011224,194,13569,69,6771,0.017491362,1.402978038,1.058956459,1.877415005,0.055634129,DB0106810011224_,2.888958432,0.338597148,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,66658,DB01592,10011224,139,6137,65,3002,0.821206935,1.046055599,0.771079974,1.431637192,0.904725148,DB0159210011224_,0.100124085,0.045026518,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iron,DB01592
,66659,DB06637,10011224,58,6104,20,1999,0.894993382,0.949723466,0.561121455,1.671443064,0.955976233,DB0663710011224_,0.045022227,-0.051584425,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dalfampridine,DB06637
,66726,DB00230,10013036,46,19628,20,8631,1,1.011379874,0.585998102,1.80602805,1,DB0023010013036_,0,0.01131561,NA,10013036,Diplopia,10015919,Eye disorders,Eye,pregabalin,DB00230
,66732,DB00451,10013036,72,47199,29,15390,0.35474323,0.809536048,0.51914225,1.29304749,0.524580917,DB0045110013036_,0.645155589,-0.211293976,NA,10013036,Diplopia,10015919,Eye disorders,Eye,levothyroxine,DB00451
,66733,DB00476,10013036,43,17214,12,6165,0.540499278,1.283302815,0.664276337,2.67526184,0.696030352,DB0047610013036_,0.36236201,0.249437079,NA,10013036,Diplopia,10015919,Eye disorders,Eye,duloxetine,DB00476
,66752,DB00318,10013573,68,4215,26,1813,0.651865905,1.124931531,0.703669057,1.848626433,0.78617341,DB0031810013573_,0.240577888,0.117722172,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,codeine,DB00318
,66754,DB00584,10013573,67,2014,51,1823,0.399797093,1.189083997,0.808959709,1.756827462,0.569668054,DB0058410013573_,0.56270145,0.17318326,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,enalapril,DB00584
,66755,DB00586,10013573,236,6873,52,2753,6.24983719160443e-05,1.817798209,1.336513274,2.512568618,0.000533453,DB0058610013573_,7.536138863,0.597625993,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,66756,DB00669,10013573,175,6202,26,1071,0.544581388,1.162288613,0.762434812,1.838498251,0.6995167,DB0066910013573_,0.357365611,0.150391003,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sumatriptan,DB00669
,66758,DB00924,10013573,325,9837,116,4135,0.137942683,1.17768601,0.946743649,1.473303441,0.266841837,DB0092410013573_,1.321099166,0.163551505,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,66759,DB01097,10013573,109,6156,26,1477,1,1.005853726,0.648117548,1.614249267,1,DB0109710013573_,0,0.00583666,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,leflunomide,DB01097
,66763,DB00005,10013916,42,128040,12,42407,0.753870193,1.159200645,0.599097274,2.419030234,0.861598714,DB0000510013916_,0.148965646,0.147730668,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,66765,DB00230,10013916,77,19597,27,8624,0.33838519,1.254972045,0.799529538,2.025823377,0.507486076,DB0023010013916_,0.678286004,0.227113297,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,66769,DB00381,10013916,49,29311,14,22873,0.000505072,2.731141518,1.483444314,5.357434326,0.003114197,DB0038110013916_,5.771784035,1.00471966,female,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,66772,DB00635,10013916,32,33021,24,23770,0.892851443,0.959769506,0.547706341,1.703308567,0.955415161,DB0063510013916_,0.045609309,-0.041062121,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,66773,DB00656,10013916,51,11962,13,6606,0.012267136,2.166434073,1.160349098,4.345456809,0.04188642,DB0065610013916_,3.172793613,0.773082532,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,66778,DB01068,10013916,68,13695,40,6800,0.412931946,0.844122098,0.562335565,1.281983379,0.582322883,DB0106810013916_,0.540730204,-0.169458129,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,66787,DB00230,10013950,120,19554,35,8616,0.035417893,1.510712945,1.028158991,2.271270721,0.096317761,DB0023010013950_,2.340102544,0.412581688,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,66789,DB00341,10013950,91,11314,34,5034,0.436703484,1.190831474,0.793752542,1.824419605,0.605245691,DB0034110013950_,0.502120802,0.174651781,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,66790,DB00343,10013950,46,8690,17,5078,0.116604072,1.581132408,0.888214183,2.945179153,0.236036815,DB0034310013950_,1.44376749,0.458141304,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,66792,DB00421,10013950,41,8862,31,5221,0.327998471,0.779219899,0.476213081,1.286854755,0.496526611,DB0042110013950_,0.700118199,-0.24946199,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,66793,DB00476,10013950,107,17150,33,6144,0.501213917,1.161589907,0.778806356,1.77430911,0.662663236,DB0047610013950_,0.411488357,0.149789676,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,66796,DB00656,10013950,75,11938,27,6592,0.0615631,1.533817643,0.975003123,2.480463271,0.146316386,DB0065610013950_,1.921983974,0.427759819,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,66798,DB00695,10013950,182,27867,117,20411,0.290639107,1.13932046,0.897588019,1.450854918,0.455923187,DB0069510013950_,0.785430932,0.130431997,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,66800,DB00820,10013950,54,11861,28,5788,0.813959778,0.941119689,0.58500728,1.544763663,0.900213863,DB0082010013950_,0.105122918,-0.060684954,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,66801,DB00956,10013950,37,5777,18,3449,0.576381814,1.227147475,0.679950792,2.293678346,0.725636228,DB0095610013950_,0.320706454,0.20469235,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,hydrocodone,DB00956
,66802,DB01068,10013950,87,13676,49,6791,0.522569926,0.881664424,0.613477126,1.27972175,0.681079914,DB0106810013950_,0.384075631,-0.125943767,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,66804,DB01373,10013950,132,22588,40,7341,0.789733959,1.072482646,0.747022748,1.570066087,0.886076516,DB0137310013950_,0.120951971,0.069976191,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,66805,DB01592,10013950,38,6238,18,3049,1,1.031832633,0.573540293,1.924071342,1,DB0159210013950_,0,0.031336477,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,66806,DB06228,10013950,37,15875,33,16043,0.633504808,1.133072451,0.688993533,1.870570734,0.772036715,DB0622810013950_,0.258723172,0.124932926,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,66807,DB06637,10013950,39,6123,13,2006,1,0.982853059,0.512336002,2.010807563,1,DB0663710013950_,0,-0.017295652,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,dalfampridine,DB06637
,66811,DB00153,10013968,312,7111,144,3295,1,1.00396065,0.817747391,1.237234262,1,DB0015310013968_,0,0.003952828,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,66812,DB00318,10013968,99,4184,20,1819,0.001143422,2.15179287,1.316279375,3.68634814,0.006154999,DB0031810013968_,5.090490728,0.766301388,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,codeine,DB00318
,66813,DB00319,10013968,74,1318,77,1776,0.129737314,1.294879455,0.920534908,1.82054791,0.25529817,DB0031910013968_,1.365323122,0.258417606,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,piperacillin,DB00319
,66814,DB01097,10013968,108,6157,27,1476,0.826337065,0.958909315,0.621420533,1.527221361,0.908343636,DB0109710013968_,0.096132518,-0.041958771,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,leflunomide,DB01097
,66817,DB00318,10016173,40,4243,17,1822,1,1.010385172,0.558250451,1.90597816,1,DB0031810016173_,0,0.010331616,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,codeine,DB00318
,66818,DB00343,10016173,323,8413,155,4940,0.042714398,1.223568193,1.003835652,1.496592149,0.111146655,DB0034310016173_,2.19690473,0.201771339,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,66819,DB00584,10016173,55,2026,41,1833,0.407959871,1.213613119,0.791045478,1.875064507,0.577386668,DB0058410016173_,0.549243101,0.193601959,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,enalapril,DB00584
,66820,DB00586,10016173,231,6878,68,2737,0.031347098,1.351724473,1.023284973,1.805329057,0.087669147,DB0058610016173_,2.434185248,0.301381165,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,diclofenac,DB00586
,66821,DB00656,10016173,427,11586,207,6412,0.128604471,1.141624504,0.961916576,1.358177805,0.253643135,DB0065610016173_,1.371826979,0.132452251,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,66822,DB00669,10016173,148,6229,15,1082,0.044074959,1.713766641,1.001101973,3.15207175,0.113746714,DB0066910016173_,2.173781107,0.538693662,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sumatriptan,DB00669
,66824,DB00924,10016173,344,9818,90,4161,3.63542680607857e-05,1.619859988,1.276997124,2.072394424,0.000335996,DB0092410016173_,7.998412023,0.482339719,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,66825,DB01097,10016173,87,6178,27,1476,0.233387374,0.769856699,0.492831142,1.23836248,0.389980429,DB0109710016173_,0.941658724,-0.261550887,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,leflunomide,DB01097
,66829,DB00318,10016256,130,4153,47,1792,0.319345996,1.193450032,0.84448305,1.711697254,0.487541935,DB0031810016256_,0.718378972,0.176848299,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,codeine,DB00318
,66830,DB00584,10016256,137,1944,108,1766,0.291319155,1.152326261,0.881299699,1.509668133,0.456758269,DB0058410016256_,0.783600981,0.141782735,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,enalapril,DB00584
,66833,DB06637,10016256,365,5797,108,1911,0.350787105,1.114089731,0.890577224,1.402831541,0.520517051,DB0663710016256_,0.652932632,0.108037687,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,66836,DB00153,10016807,42,7381,17,3422,0.676764234,1.145399856,0.637138013,2.149409532,0.803963008,DB0015310016807_,0.218202021,0.135753795,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,ergocalciferol,DB00153
,66837,DB00230,10016807,114,19560,36,8615,0.090979322,1.39475774,0.950418801,2.091210718,0.196814245,DB0023010016807_,1.625494914,0.332720737,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,pregabalin,DB00230
,66840,DB00381,10016807,294,29066,146,22741,5.39267836635755e-06,1.575485072,1.286543898,1.936241522,6.316691214782e-05,DB0038110016807_,9.669729936,0.454563207,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,66842,DB00476,10016807,83,17174,15,6162,0.011288666,1.985374538,1.135987102,3.708562586,0.03919472,DB0047610016807_,3.239213247,0.68580758,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,duloxetine,DB00476
,66844,DB00656,10016807,49,11964,23,6596,0.621888778,1.174521512,0.701336715,2.021847393,0.762110651,DB0065610016807_,0.271663522,0.160860841,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,trazodone,DB00656
,66847,DB00924,10016807,59,10103,19,4232,0.383532103,1.300695481,0.763377337,2.313409324,0.55354389,DB0092410016807_,0.591414235,0.262899106,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,cyclobenzaprine,DB00924
,66849,DB01068,10016807,62,13701,20,6820,0.099991855,1.543068938,0.918461967,2.699616845,0.210777168,DB0106810016807_,1.556953779,0.43377325,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,clonazepam,DB01068
,66855,DB00005,10016946,37,128045,13,42406,0.870220914,0.942585673,0.489627205,1.932697814,0.94233451,DB0000510016946_,0.059394961,-0.059128464,NA,10016946,Food allergy,10021428,Immune system disorders,Immun,etanercept,DB00005
,66895,DB00451,10017076,45,47226,7,15412,0.074981521,2.097792208,0.938878136,5.515628456,0.169806853,DB0045110017076_,1.773093647,0.740885462,NA,10017076,Fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,66915,DB00153,10017577,147,7276,50,3389,0.063267564,1.369380659,0.98440239,1.932455296,0.149414908,DB0015310017577_,1.901028228,0.314358564,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,66917,DB00341,10017577,130,11275,52,5016,0.5720435,1.112184847,0.798946386,1.567974199,0.722122,DB0034110017577_,0.325561179,0.106326411,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,66918,DB00413,10017577,55,2144,41,1166,0.131308442,0.72964202,0.474873561,1.128829739,0.257628006,DB0041310017577_,1.356238574,-0.315201249,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,pramipexole,DB00413
,66919,DB00421,10017577,124,8779,48,5204,0.01358383,1.531299806,1.086962245,2.187856712,0.045443676,DB0042110017577_,3.091281606,0.426116921,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,66920,DB00476,10017577,309,16948,76,6101,0.002873063,1.463543372,1.13327651,1.910133569,0.01305193,DB0047610017577_,4.338819265,0.380860462,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,66923,DB00924,10017577,168,9994,48,4203,0.019537894,1.471933308,1.059877132,2.077692286,0.060696555,DB0092410017577_,2.801868331,0.386576712,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,66924,DB00956,10017577,94,5720,36,3431,0.022339059,1.566138455,1.053344863,2.373985796,0.067391504,DB0095610017577_,2.697236319,0.448613007,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,66925,DB01097,10017577,82,6183,27,1476,0.17799373,0.725032113,0.462339446,1.169884595,0.321307959,DB0109710017577_,1.135355242,-0.321539332,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,66930,DB00584,10019211,98,1983,50,1824,0.000752046,1.802575837,1.261412511,2.603373278,0.004342123,DB0058410019211_,5.439391796,0.589216662,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,enalapril,DB00584
,66931,DB00656,10019211,615,11398,165,6454,5.77096501616761e-19,2.110450079,1.76941591,2.528512073,5.42718481037444e-17,DB0065610019211_,37.45252603,0.746901232,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,66937,DB00341,10020772,138,11267,50,5018,0.233399102,1.229188887,0.881792611,1.737759769,0.389987629,DB0034110020772_,0.941640261,0.20635451,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,cetirizine,DB00341
,66939,DB00586,10020772,100,7009,23,2782,0.015696605,1.725659074,1.085483116,2.852321134,0.051090986,DB0058610020772_,2.974147206,0.54560905,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,diclofenac,DB00586
,66940,DB00656,10020772,139,11874,62,6557,0.18221412,1.238060363,0.909900992,1.700869991,0.326660629,DB0065610020772_,1.118833479,0.213545932,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,trazodone,DB00656
,66941,DB00669,10020772,52,6325,10,1087,0.718660313,0.893704268,0.447551653,1.978424799,0.833884533,DB0066910020772_,0.181660336,-0.112380355,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,sumatriptan,DB00669
,66943,DB00820,10020772,94,11821,54,5762,0.334771501,0.848521636,0.599885644,1.210700124,0.503951579,DB0082010020772_,0.68527509,-0.164259696,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,tadalafil,DB00820
,66944,DB00956,10020772,77,5737,33,3434,0.113488809,1.396616738,0.915390849,2.173320763,0.231361022,DB0095610020772_,1.463775921,0.334052696,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,hydrocodone,DB00956
,66946,DB01592,10020772,82,6194,28,3039,0.102842493,1.436810701,0.923134971,2.297739413,0.215258396,DB0159210020772_,1.535916131,0.362425866,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,iron,DB01592
,66947,DB06228,10020772,107,15805,108,15968,1,1.000958418,0.758176813,1.32129449,1,DB0622810020772_,0,0.000957959,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,rivaroxaban,DB06228
,66951,DB00230,10021654,48,19626,20,8631,0.895825091,1.055454654,0.614213744,1.878603137,0.956213706,DB0023010021654_,0.044773849,0.053971626,NA,10021654,Increased appetite,10027433,Metabolism and nutrition disorders,Metab,pregabalin,DB00230
,66955,DB00381,10021654,35,29325,16,22871,0.08953074,1.706038124,0.91943693,3.302054835,0.194496921,DB0038110021654_,1.637338946,0.534173796,NA,10021654,Increased appetite,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,66981,DB00476,10022116,55,17202,14,6163,0.276527618,1.407445698,0.771504441,2.742866758,0.439983562,DB0047610022116_,0.821017912,0.3417765,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,66986,DB01068,10022116,54,13709,20,6820,0.322312877,1.343216816,0.790236256,2.371032418,0.490660758,DB0106810022116_,0.712002311,0.295067346,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,66989,DB06228,10022116,25,15887,33,16043,0.35807388,0.765023194,0.435908289,1.326965002,0.527795557,DB0622810022116_,0.639046272,-0.267849127,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,67033,DB00451,10023874,52,47219,7,15412,0.022535749,2.424732118,1.096755865,6.328565918,0.067809761,DB0045110023874_,2.691049124,0.885721051,NA,10023874,Laryngitis,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,67054,DB00153,10024855,63,7360,20,3419,0.155400247,1.463252518,0.871216817,2.55964523,0.291361607,DB0015310024855_,1.233190149,0.38066171,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,67056,DB00341,10024855,95,11310,25,5043,0.017114249,1.694328103,1.079546287,2.751729118,0.05467283,DB0034110024855_,2.9063884,0.527286263,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,67057,DB00381,10024855,201,29159,165,22722,0.634439158,0.949291791,0.768149648,1.174368769,0.772713667,DB0038110024855_,0.257846716,-0.052039055,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,67059,DB00421,10024855,111,8792,39,5213,0.004882945,1.687497927,1.159892598,2.50134865,0.020079506,DB0042110024855_,3.908055581,0.523246915,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,67060,DB00476,10024855,128,17129,78,6099,0.00032268,0.584323638,0.43683059,0.785848569,0.00214156,DB0047610024855_,6.146220956,-0.537300276,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,67062,DB00656,10024855,84,11929,37,6582,0.294499095,1.252679808,0.840252093,1.899724519,0.460387872,DB0065610024855_,0.775685946,0.225285103,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,67065,DB00956,10024855,42,5772,23,3444,0.797873251,1.08957965,0.639196557,1.901635223,0.890778357,DB0095610024855_,0.11565964,0.08579198,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,67066,DB01068,10024855,132,13631,62,6778,0.759548167,1.05865533,0.775970487,1.457881997,0.866110952,DB0106810024855_,0.143742258,0.056999547,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,67069,DB01373,10024855,120,22600,34,7347,0.512341341,1.147364068,0.77754119,1.734020559,0.672537562,DB0137310024855_,0.396697315,0.137467197,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,calcium,DB01373
,67070,DB01592,10024855,54,6222,17,3050,0.127720206,1.557025519,0.887041331,2.870116477,0.252419274,DB0159210024855_,1.376663789,0.442777283,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,iron,DB01592
,67075,DB00153,10027175,71,7352,33,3406,1,0.996744114,0.649342557,1.55877487,1,DB0015310027175_,0,-0.003261198,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,67076,DB00230,10027175,574,19100,169,8482,1.81105280448398e-06,1.508287953,1.265824023,1.804789156,2.42751264486799e-05,DB0023010027175_,10.62605833,0.410975202,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,67079,DB00341,10027175,118,11287,27,5041,0.001089552,1.951826165,1.274211543,3.08961602,0.005911324,DB0034110027175_,5.130885452,0.668765429,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,67080,DB00343,10027175,93,8643,23,5072,9.4192854588559e-05,2.372714869,1.488015571,3.931191767,0.000757607,DB0034310027175_,7.185345976,0.864034814,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,67081,DB00381,10027175,299,29061,129,22758,6.44574809296292e-09,1.815084859,1.470521637,2.250845165,1.51206147812165e-07,DB0038110027175_,15.70462171,0.596132221,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,67082,DB00413,10027175,39,2160,14,1193,0.193458271,1.538409711,0.813195603,3.080498179,0.341003933,DB0041310027175_,1.075861269,0.430749228,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,pramipexole,DB00413
,67083,DB00421,10027175,117,8786,32,5220,5.29826828597492e-05,2.172167623,1.455943317,3.325516876,0.000464217,DB0042110027175_,7.675159291,0.775725573,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,67085,DB00586,10027175,82,7027,21,2784,0.078603779,1.546998542,0.946293005,2.63676464,0.175980609,DB0058610027175_,1.737381467,0.436316629,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,67086,DB00656,10027175,171,11842,59,6560,0.001403535,1.605508123,1.185663318,2.200242726,0.007273642,DB0065610027175_,4.923498154,0.473440294,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,67087,DB00669,10027175,63,6314,6,1091,0.228711507,1.814178457,0.785901565,5.142705408,0.384312269,DB0066910027175_,0.956299856,0.595632725,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,sumatriptan,DB00669
,67088,DB00695,10027175,331,27718,118,20410,2.18006212353271e-12,2.065462392,1.667749751,2.572667391,9.28734731232696e-11,DB0069510027175_,23.09978305,0.72535412,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,67090,DB00924,10027175,135,10027,34,4217,0.006513434,1.669835331,1.136999969,2.513765652,0.025283263,DB0092410027175_,3.677612644,0.512725017,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,67091,DB01068,10027175,223,13540,69,6771,0.000436295,1.61614597,1.226465339,2.152559451,0.002756071,DB0106810027175_,5.893949137,0.480044284,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,67093,DB01592,10027175,87,6189,26,3041,0.026350822,1.644071796,1.047869471,2.661175903,0.076525396,DB0159210027175_,2.570132618,0.497175967,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,iron,DB01592
,67094,DB06228,10027175,86,15826,44,16032,0.000199112,1.979933892,1.36041935,2.91779296,0.00143447,DB0622810027175_,6.546960045,0.683063456,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,67095,DB06637,10027175,131,6031,34,1985,0.236578592,1.268083364,0.860593286,1.91452277,0.39382055,DB0663710027175_,0.93185993,0.237506598,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,67109,DB00635,10028034,63,32990,29,23765,0.044913856,1.564926796,0.992697298,2.521140639,0.115407468,DB0063510028034_,2.159286212,0.447839047,NA,10028034,Mouth ulceration,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,67118,DB01097,10028034,44,6221,8,1495,0.597342261,1.321685116,0.613753444,3.257512469,0.742483875,DB0109710028034_,0.297754126,0.278907526,NA,10028034,Mouth ulceration,10017947,Gastrointestinal disorders,Gastr,leflunomide,DB01097
,67128,DB00230,10028035,124,19550,24,8627,7.45098688397196e-05,2.279884991,1.462692569,3.695142653,0.000619286,DB0023010028035_,7.386943393,0.824124999,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,67133,DB00381,10028035,33,29327,22,22865,0.589862256,1.16947349,0.661473781,2.106188395,0.736574711,DB0038110028035_,0.305744607,0.156553639,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,67136,DB00451,10028035,61,47210,16,15403,0.508744174,1.243876509,0.707931614,2.312201095,0.669286317,DB0045110028035_,0.401543333,0.21823272,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,67137,DB00476,10028035,31,17226,21,6156,0.026887984,0.527585663,0.293352952,0.966735935,0.077767459,DB0047610028035_,2.554032205,-0.639444033,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,67143,DB00695,10028035,35,28014,15,20513,0.086376656,1.708538639,0.90895639,3.368047759,0.189003987,DB0069510028035_,1.66598717,0.535638408,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,67157,DB00230,10028245,74,19600,20,8631,0.05612494,1.629296067,0.982630189,2.821614594,0.136312687,DB0023010028245_,1.992803861,0.488148061,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,67165,DB00476,10028245,73,17184,18,6159,0.189075945,1.453507264,0.857838108,2.590030772,0.335359574,DB0047610028245_,1.092551969,0.373979439,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,67168,DB00656,10028245,43,11970,14,6605,0.096063635,1.694757878,0.908650013,3.356615761,0.204861351,DB0065610028245_,1.585421865,0.527539886,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,67170,DB00695,10028245,47,28002,10,20518,0.000125018,3.443729058,1.716859256,7.647237732,0.000965365,DB0069510028245_,6.943003854,1.236554913,female,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,67173,DB00924,10028245,43,10119,10,4241,0.097711703,1.802119676,0.890696871,4.025316337,0.207442122,DB0092410028245_,1.57290291,0.58896357,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,67184,DB00343,10028372,78,8658,44,5051,0.924983035,1.034192656,0.704487192,1.535117079,0.967765755,DB0034310028372_,0.032765209,0.03362108,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,diltiazem,DB00343
,67185,DB00381,10028372,230,29130,178,22709,0.960082467,1.007315211,0.824039516,1.23298791,0.99769778,DB0038110028372_,0.002304874,0.007288585,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,67187,DB00421,10028372,63,8840,45,5207,0.319587461,0.824658423,0.552726662,1.239220245,0.487783085,DB0042110028372_,0.717884469,-0.192786011,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,spironolactone,DB00421
,67189,DB00656,10028372,98,11915,45,6574,0.33524724,1.201527124,0.834820052,1.75275242,0.504463803,DB0065610028372_,0.684259189,0.183593351,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,67190,DB00669,10028372,44,6333,9,1088,0.563330758,0.839937986,0.403205997,1.962615358,0.715338486,DB0066910028372_,0.334999442,-0.174427216,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,sumatriptan,DB00669
,67192,DB00924,10028372,83,10079,39,4212,0.550424289,0.889388784,0.599808527,1.339131253,0.704634236,DB0092410028372_,0.350076426,-0.117220812,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,67195,DB01592,10028372,52,6224,17,3050,0.158434777,1.498881273,0.851120439,2.769751626,0.295393539,DB0159210028372_,1.219446783,0.404719012,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,iron,DB01592
,67199,DB06637,10028813,188,5974,48,1971,0.125520201,1.292171224,0.932493531,1.820914914,0.249394469,DB0663710028813_,1.388719425,0.256323923,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dalfampridine,DB06637
,67201,DB00005,10030095,107,127975,23,42396,0.067067522,1.541142036,0.975145561,2.535331289,0.156091419,DB0000510030095_,1.857313423,0.432523724,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,67202,DB00230,10030095,121,19553,45,8606,0.353759501,1.183461664,0.833154716,1.707402655,0.523612269,DB0023010030095_,0.647003812,0.168443758,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,67205,DB00343,10030095,141,8595,44,5051,0.000158401,1.883126028,1.331140348,2.710473477,0.001181994,DB0034310030095_,6.740552585,0.632933177,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,67211,DB01068,10030095,61,13702,14,6826,0.006636921,2.170550901,1.199160138,4.205053206,0.025681064,DB0106810030095_,3.662001372,0.774981007,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,67214,DB01592,10030095,59,6217,15,3052,0.024510504,1.930801034,1.079331806,3.67099153,0.072418832,DB0159210030095_,2.625288898,0.65793496,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,67224,DB00381,10031127,36,29324,34,22853,0.469951702,0.825176774,0.501729759,1.359748526,0.636211397,DB0038110031127_,0.452224386,-0.192157644,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,67226,DB00421,10031127,17,8886,33,5219,4.63849233273721e-05,0.30258959,0.157912054,0.559714198,0.000414281,DB0042110031127_,7.788967115,-1.19537788,male,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,spironolactone,DB00421
,67227,DB00451,10031127,51,47220,51,15368,4.39169181043668e-08,0.325477176,0.216284328,0.489769165,8.58576565543535e-07,DB0045110031127_,13.96798998,-1.122462941,male,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,67234,DB00695,10031127,39,28010,60,20468,0.000316732,0.474982306,0.308836126,0.722991628,0.00210927,DB0069510031127_,6.161413216,-0.744477727,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,furosemide,DB00695
,67248,DB00318,10033371,67,4216,19,1820,0.123202689,1.522188114,0.900308974,2.691706817,0.245950991,DB0031810033371_,1.402622987,0.420148849,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,codeine,DB00318
,67249,DB00343,10033371,300,8436,96,4999,7.87346441697493e-08,1.851732587,1.462679609,2.361687763,1.45742262112807e-06,DB0034310033371_,13.43884101,0.616121734,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,67250,DB00413,10033371,95,2104,34,1173,0.030614772,1.557557436,1.035119563,2.393307665,0.086053871,DB0041310033371_,2.452781773,0.443118848,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,pramipexole,DB00413
,67252,DB06637,10033371,163,5999,49,1970,0.628885093,1.092380658,0.785822032,1.542170762,0.76802698,DB0663710033371_,0.263930417,0.088359404,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,67255,DB00421,10033425,298,8605,91,5161,5.30269074517924e-09,1.963985293,1.543886748,2.518317331,1.26710205670033e-07,DB0042110033425_,15.8813632,0.674975722,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,spironolactone,DB00421
,67256,DB00656,10033425,257,11756,89,6530,0.00010926,1.603933415,1.253143422,2.068881803,0.000860107,DB0065610033425_,7.058453455,0.472458997,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,67258,DB00924,10033425,266,9896,83,4168,0.017433519,1.349726197,1.048212416,1.753301416,0.055473646,DB0092410033425_,2.891847213,0.299901755,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,67260,DB06637,10033425,121,6041,33,1986,0.395802511,1.205397515,0.811351046,1.835635599,0.565447524,DB0663710033425_,0.570137783,0.186809401,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,dalfampridine,DB06637
,67263,DB14512,10033425,60,4784,25,2387,0.488869027,1.197440903,0.737358319,1.998441005,0.652373697,DB1451210033425_,0.427137727,0.180186699,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,mometasone furoate,DB14512
,67302,DB00635,10034829,55,32998,19,23775,0.004493115,2.085612845,1.218200591,3.722310146,0.018753715,DB0063510034829_,3.976363413,0.735062742,NA,10034829,Pharyngeal oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,67317,DB00318,10035664,94,4189,58,1781,0.031294436,0.689098727,0.489073197,0.977870136,0.087560858,DB0031810035664_,2.43542121,-0.372370728,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,codeine,DB00318
,67318,DB00413,10035664,72,2127,47,1160,0.379997952,0.835513742,0.566302201,1.24266953,0.550119581,DB0041310035664_,0.597619604,-0.179708483,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pramipexole,DB00413
,67319,DB00476,10035664,449,16808,223,5954,7.42452160205624e-05,0.713248842,0.604373988,0.843617876,0.000617282,DB0047610035664_,7.390185377,-0.337924913,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,duloxetine,DB00476
,67320,DB00669,10035664,90,6287,19,1078,0.412889892,0.812236734,0.488740963,1.417408497,0.582294818,DB0066910035664_,0.540778399,-0.207963437,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sumatriptan,DB00669
,67322,DB00924,10035664,298,9864,179,4072,0.000125132,0.687274213,0.566925384,0.834995375,0.000966102,DB0092410035664_,6.942241197,-0.37502192,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cyclobenzaprine,DB00924
,67323,DB01097,10035664,112,6153,33,1470,0.289355982,0.810862166,0.543105202,1.23993677,0.45449353,DB0109710035664_,0.788571601,-0.209657195,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,leflunomide,DB01097
,67325,DB06637,10035664,70,6092,29,1990,0.291564812,0.788508922,0.503066693,1.264995662,0.457007132,DB0663710035664_,0.783056283,-0.237611557,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,dalfampridine,DB06637
,67328,DB00318,10037087,69,4214,25,1814,0.498296588,1.188052662,0.739345485,1.966585573,0.660264011,DB0031810037087_,0.415115508,0.172315548,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,codeine,DB00318
,67329,DB00319,10037087,34,1358,26,1827,0.034760022,1.758969726,1.019308284,3.068449801,0.094960992,DB0031910037087_,2.354289084,0.564728255,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,piperacillin,DB00319
,67330,DB00341,10037087,371,11034,118,4950,0.001200943,1.410463181,1.140298791,1.755047383,0.006412574,DB0034110037087_,5.049494529,0.343918148,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,cetirizine,DB00341
,67331,DB00413,10037087,45,2154,10,1197,0.006539097,2.500127277,1.236478399,5.584309431,0.025360408,DB0041310037087_,3.674566054,0.916341641,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,pramipexole,DB00413
,67332,DB00421,10037087,200,8703,79,5173,0.002114024,1.504750172,1.151350383,1.982718806,0.010181788,DB0042110037087_,4.58715465,0.408626885,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,spironolactone,DB00421
,67333,DB00584,10037087,45,2036,29,1845,0.160333523,1.406031347,0.858416946,2.335992417,0.297950911,DB0058410037087_,1.210826535,0.340771089,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,enalapril,DB00584
,67334,DB00656,10037087,201,11812,64,6555,7.48403460658038e-05,1.742822924,1.307053968,2.350753524,0.000621541,DB0065610037087_,7.383308054,0.555506169,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,trazodone,DB00656
,67335,DB00669,10037087,82,6295,13,1084,0.884510377,1.086197638,0.598614885,2.133838215,0.951918915,DB0066910037087_,0.049275421,0.082683192,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,sumatriptan,DB00669
,67337,DB00820,10037087,193,11722,51,5765,4.6373790479932e-05,1.861106035,1.358208403,2.590601797,0.000414269,DB0082010037087_,7.788996116,0.621170953,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,tadalafil,DB00820
,67338,DB00924,10037087,220,9942,42,4209,4.82204065173434e-07,2.217474034,1.584735901,3.169301538,7.51763573729758e-06,DB0092410037087_,11.79825887,0.796368726,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,cyclobenzaprine,DB00924
,67339,DB01097,10037087,125,6140,14,1489,0.004545439,2.165033959,1.238712832,4.087113446,0.01892403,DB0109710037087_,3.96732274,0.772436047,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,leflunomide,DB01097
,67341,DB06228,10037087,199,15713,120,15956,6.08866420794064e-06,1.683940856,1.33438735,2.132476922,7.02394288811585e-05,DB0622810037087_,9.56360074,0.521136794,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,rivaroxaban,DB06228
,67344,DB14512,10037087,82,4762,27,2385,0.064905381,1.520988055,0.970939261,2.451832941,0.152290822,DB1451210037087_,1.881963284,0.41936016,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,mometasone furoate,DB14512
,67345,DB00318,10037844,115,4168,27,1812,0.002992028,1.851511083,1.204001025,2.940634434,0.013480539,DB0031810037844_,4.306508186,0.616002107,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,codeine,DB00318
,67346,DB00413,10037844,40,2159,21,1186,1,1.046328849,0.599170807,1.877180924,1,DB0041310037844_,0,0.045287703,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,pramipexole,DB00413
,67347,DB00656,10037844,292,11721,95,6524,3.54784627246512e-06,1.710790324,1.349912108,2.184286678,4.37714805312114e-05,DB0065610037844_,10.03652808,0.536955441,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,trazodone,DB00656
,67348,DB00669,10037844,130,6247,17,1080,0.345628576,1.322000085,0.790565683,2.348545955,0.515043206,DB0066910037844_,0.663504487,0.279145805,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sumatriptan,DB00669
,67350,DB00820,10037844,265,11650,91,5725,0.002997684,1.431020301,1.121164524,1.840456396,0.01350139,DB0082010037844_,4.30496261,0.358387687,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,tadalafil,DB00820
,67351,DB01097,10037844,272,5993,47,1456,0.035537882,1.405940904,1.022485176,1.969947149,0.096579119,DB0109710037844_,2.337392722,0.340706761,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,leflunomide,DB01097
,67353,DB01592,10037844,168,6108,79,2988,0.836830636,1.040309596,0.788568107,1.382115248,0.915738214,DB0159210037844_,0.088024748,0.039518357,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,iron,DB01592
,67356,DB14512,10037844,112,4732,44,2368,0.197540629,1.273807439,0.887810659,1.855521393,0.346030151,DB1451210037844_,1.061229367,0.242010399,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,mometasone furoate,DB14512
,67357,DB00005,10038776,50,128032,18,42401,0.779178429,0.919922256,0.527369767,1.675618152,0.879672513,DB0000510038776_,0.128205585,-0.083466116,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,67365,DB00451,10038776,85,47186,23,15396,0.502233623,1.205821168,0.753041756,2.0043686,0.66352747,DB0045110038776_,0.410185025,0.187160802,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,67369,DB00635,10038776,34,33019,18,23776,0.326518625,1.360124488,0.746680469,2.558729878,0.495009277,DB0063510038776_,0.703178774,0.307576231,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,67373,DB00820,10038776,44,11871,10,5806,0.028504363,2.151920598,1.066044173,4.799445068,0.081385747,DB0082010038776_,2.508555119,0.766360745,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,67411,DB00005,10040799,58,128024,17,42402,0.789312447,1.129986218,0.648844058,2.070063076,0.885851185,DB0000510040799_,0.121206306,0.122205436,NA,10040799,Skin atrophy,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,67447,DB00381,10040984,94,29266,56,22831,0.117581277,1.309479708,0.930337929,1.857940573,0.237557562,DB0038110040984_,1.43734532,0.269629889,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,67450,DB00476,10040984,421,16836,130,6047,0.142212975,1.163149021,0.951076421,1.430265418,0.272873487,DB0047610040984_,1.298747009,0.151131001,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,67452,DB00656,10040984,58,11955,31,6588,1,1.031027236,0.654867364,1.651737644,1,DB0065610040984_,0,0.030555622,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,67454,DB00695,10040984,70,27979,45,20483,0.510087339,1.138761742,0.771705338,1.695672175,0.670606515,DB0069510040984_,0.399572729,0.129941481,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,67456,DB00820,10040984,41,11874,27,5789,0.244312563,0.740318299,0.444096469,1.252856299,0.402884852,DB0082010040984_,0.909104485,-0.300675052,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,tadalafil,DB00820
,67457,DB00924,10040984,54,10108,16,4235,0.239804557,1.414066108,0.796179933,2.6500422,0.39763202,DB0092410040984_,0.922228275,0.346469319,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,67458,DB00956,10040984,44,5770,10,3457,0.004308285,2.635939512,1.304914892,5.882330408,0.018142147,DB0095610040984_,4.0095175,0.96923967,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,hydrocodone,DB00956
,67459,DB01068,10040984,75,13688,34,6806,0.684819325,1.096809426,0.721358845,1.698670805,0.809622937,DB0106810040984_,0.21118665,0.092405443,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,67496,DB00005,10041591,62,128020,17,42402,0.602453592,1.207950165,0.697212078,2.2043628,0.746381968,DB0000510041591_,0.292517788,0.188924845,NA,10041591,Spinal osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,67498,DB00230,10041591,50,19624,11,8640,0.036252538,2.001217874,1.027711617,4.265090338,0.09803477,DB0023010041591_,2.322433064,0.693755932,NA,10041591,Spinal osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,67505,DB00451,10041591,62,47209,11,15408,0.057837953,1.839486691,0.960068496,3.875384194,0.139396845,DB0045110041591_,1.970430416,0.60948656,NA,10041591,Spinal osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,67518,DB01373,10041591,52,22668,8,7373,0.04969768,2.114022822,0.996725636,5.155805414,0.124457271,DB0137310041591_,2.083792827,0.748592683,NA,10041591,Spinal osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,67525,DB00230,10043071,50,19624,13,8638,0.100133802,1.692953738,0.905441415,3.399169036,0.210974871,DB0023010043071_,1.55601625,0.526474778,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,pregabalin,DB00230
,67527,DB00319,10043071,41,1351,41,1812,0.213823594,1.341090286,0.843171533,2.133175129,0.366009921,DB0031910043071_,1.00509484,0.293482929,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,piperacillin,DB00319
,67528,DB00341,10043071,62,11343,35,5033,0.270103521,0.785982011,0.510524472,1.227648017,0.43273526,DB0034110043071_,0.837629148,-0.240821373,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,cetirizine,DB00341
,67529,DB00343,10043071,86,8650,36,5059,0.108615719,1.39712242,0.934901321,2.126447202,0.223962672,DB0034310043071_,1.496275882,0.334414707,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,diltiazem,DB00343
,67531,DB00421,10043071,76,8827,30,5222,0.068862316,1.498663907,0.968765283,2.372908583,0.159277472,DB0042110043071_,1.83710749,0.404573983,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,spironolactone,DB00421
,67532,DB00451,10043071,218,47053,83,15336,0.227651755,0.856085981,0.661442539,1.116804497,0.382922503,DB0045110043071_,0.959922652,-0.155384463,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,67534,DB00656,10043071,79,11934,27,6592,0.032280102,1.616158738,1.031148056,2.605925093,0.089724789,DB0065610043071_,2.411008191,0.480052184,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,trazodone,DB00656
,67536,DB00695,10043071,189,27860,113,20415,0.090332601,1.225602552,0.965013594,1.562437672,0.195761597,DB0069510043071_,1.630857703,0.203432602,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,furosemide,DB00695
,67538,DB01068,10043071,70,13693,49,6791,0.078320989,0.708485207,0.484231743,1.043809898,0.175579291,DB0106810043071_,1.739664536,-0.3446261,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,clonazepam,DB01068
,67541,DB01373,10043071,66,22654,26,7355,0.396916067,0.824140842,0.515861439,1.353234468,0.566530305,DB0137310043071_,0.568224705,-0.193413839,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,calcium,DB01373
,67542,DB01592,10043071,34,6242,21,3046,0.390904949,0.79011394,0.444696724,1.43518685,0.560751853,DB0159210043071_,0.5784768,-0.235578117,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,iron,DB01592
,67543,DB06228,10043071,53,15859,23,16053,0.000503031,2.332598043,1.404227602,3.98961021,0.003105617,DB0622810043071_,5.774542924,0.846982686,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,67553,DB00381,10043882,62,29298,51,22836,0.776755707,0.947581169,0.643350066,1.401181151,0.878377873,DB0038110043882_,0.129678399,-0.053842679,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,amlodipine,DB00381
,67556,DB00476,10043882,511,16746,191,5986,0.601902224,0.956341073,0.806107667,1.138312984,0.746062434,DB0047610043882_,0.292945991,-0.044640659,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,duloxetine,DB00476
,67558,DB00635,10043882,77,32976,27,23767,0.000946847,2.055394792,1.310077233,3.316131415,0.005263934,DB0063510043882_,5.246876599,0.720467942,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,prednisone,DB00635
,67559,DB00656,10043882,35,11978,21,6598,0.78046686,0.918077879,0.519234749,1.661197507,0.880475612,DB0065610043882_,0.12729305,-0.085473056,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,trazodone,DB00656
,67562,DB00924,10043882,59,10103,15,4236,0.095959648,1.649126569,0.922434942,3.133824885,0.204723782,DB0092410043882_,1.586093613,0.500245795,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,cyclobenzaprine,DB00924
,67564,DB01068,10043882,53,13710,22,6818,0.539938462,1.198013026,0.715561776,2.070449405,0.695563736,DB0106810043882_,0.363032631,0.180664372,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,clonazepam,DB01068
,67574,DB00230,10044034,34,19640,18,8633,0.547425061,0.830308846,0.455678715,1.562534705,0.702076981,DB0023010044034_,0.353712222,-0.185957543,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,67579,DB00381,10044034,78,29282,48,22839,0.208866772,1.267440096,0.873106693,1.856492657,0.359945131,DB0038110044034_,1.021803673,0.236999194,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,67582,DB00451,10044034,156,47115,40,15379,0.18433903,1.273000866,0.893977499,1.850846468,0.329336882,DB0045110044034_,1.110674093,0.241377,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,67585,DB00635,10044034,79,32974,26,23768,0.000325767,2.190108719,1.389992608,3.556787955,0.002158502,DB0063510044034_,6.138340823,0.783951186,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,67588,DB00695,10044034,59,27990,36,20492,0.407446299,1.199849298,0.779233483,1.870740755,0.576908316,DB0069510044034_,0.550071923,0.182195964,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,67596,DB01373,10044034,151,22569,48,7333,0.934295758,1.022134041,0.733341749,1.44709416,0.97479454,DB0137310044034_,0.025528558,0.021892639,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,67603,DB00153,10046735,90,7333,19,3420,0.000888941,2.209055093,1.333337238,3.845233492,0.005001779,DB0015310046735_,5.29796154,0.792564864,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,ergocalciferol,DB00153
,67604,DB00230,10046735,148,19526,32,8619,0.000122765,2.041483805,1.384258357,3.095564269,0.000950763,DB0023010046735_,6.958245621,0.713676899,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,67605,DB00318,10046735,84,4199,14,1825,0.00034094,2.607436055,1.466132137,4.986454943,0.002244049,DB0031810046735_,6.099473671,0.958367384,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,codeine,DB00318
,67608,DB00421,10046735,70,8833,12,5240,9.27117642683306e-06,3.460258906,1.859132336,7.021607219,0.000101669,DB0042110046735_,9.193791774,1.241343415,female,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,spironolactone,DB00421
,67609,DB00656,10046735,98,11915,26,6593,0.00063588,2.085577219,1.340435198,3.352835366,0.003782329,DB0065610046735_,5.57741526,0.735045661,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,trazodone,DB00656
,67610,DB00669,10046735,65,6312,14,1083,0.424763094,0.796646296,0.44055799,1.542877478,0.593561826,DB0066910046735_,0.521613899,-0.227344493,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,sumatriptan,DB00669
,67612,DB00820,10046735,70,11845,27,5789,0.329922148,1.267018198,0.801181823,2.057614491,0.498570572,DB0082010046735_,0.69601013,0.236666265,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,tadalafil,DB00820
,67613,DB00956,10046735,51,5763,18,3449,0.060430005,1.695583203,0.97202049,3.089314104,0.144202592,DB0095610046735_,1.936536077,0.528026754,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocodone,DB00956
,67614,DB01097,10046735,80,6185,12,1491,0.143826785,1.607012885,0.868134049,3.248527204,0.27526482,DB0109710046735_,1.290021662,0.474377105,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,leflunomide,DB01097
,67616,DB01373,10046735,174,22546,34,7347,0.005782723,1.667585192,1.148304012,2.487233155,0.022990075,DB0137310046735_,3.772692687,0.511376587,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,67617,DB01592,10046735,54,6222,14,3053,0.037192359,1.892501968,1.034723067,3.695378007,0.099936341,DB0159210046735_,2.303221887,0.637899746,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,iron,DB01592
,67618,DB06228,10046735,81,15831,50,16026,0.006449721,1.639918997,1.13793187,2.383683931,0.025078537,DB0622810046735_,3.685742899,0.494646849,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,rivaroxaban,DB06228
,67619,DB06637,10046735,45,6117,8,2011,0.111929519,1.849038627,0.860776841,4.550098891,0.228982226,DB0663710046735_,1.474110895,0.614665843,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,dalfampridine,DB06637
,67621,DB14512,10046735,61,4783,20,2392,0.122470352,1.525236663,0.905032641,2.675239371,0.244996629,DB1451210046735_,1.406510828,0.422149587,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,mometasone furoate,DB14512
,67625,DB00381,10047340,101,29259,33,22854,4.68260214474621e-06,2.390539758,1.598720072,3.659194912,5.58575890059697e-05,DB0038110047340_,9.79270516,0.87151918,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,amlodipine,DB00381
,67628,DB00476,10047340,1037,16220,327,5850,0.03957632,1.143751901,1.005349372,1.30381171,0.10481245,DB0047610047340_,2.255582712,0.134313999,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,duloxetine,DB00476
,67631,DB00656,10047340,58,11955,13,6606,0.001795146,2.465217942,1.333754163,4.908225502,0.008901229,DB0065610047340_,4.721565931,0.902280218,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,trazodone,DB00656
,67633,DB00695,10047340,78,27971,25,20503,0.000189976,2.286929765,1.440791394,3.747175075,0.001379805,DB0069510047340_,6.585812972,0.827210204,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,furosemide,DB00695
,67635,DB00820,10047340,49,11866,15,5801,0.141445145,1.596955536,0.879858351,3.068852234,0.271864695,DB0082010047340_,1.302450781,0.468099027,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,tadalafil,DB00820
,67636,DB00924,10047340,56,10106,12,4239,0.032607308,1.957372974,1.035758772,4.016375606,0.090438229,DB0092410047340_,2.403088215,0.671603255,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,cyclobenzaprine,DB00924
,67638,DB01068,10047340,78,13685,22,6818,0.018727083,1.766335793,1.087722971,2.9812269,0.058673506,DB0106810047340_,2.835767008,0.568907227,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,clonazepam,DB01068
,67646,DB00586,10047700,215,6894,60,2745,0.014549345,1.426790101,1.063109625,1.939415835,0.048095269,DB0058610047700_,3.03457146,0.355427236,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,diclofenac,DB00586
,67647,DB00656,10047700,388,11625,143,6476,2.20545806407882e-05,1.511473021,1.241468834,1.84856204,0.000217134,DB0065610047700_,8.434994213,0.413084686,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,67650,DB01592,10047700,220,6056,57,3010,6.51233353667553e-06,1.918233637,1.422482839,2.623066559,7.45056309081681e-05,DB0159210047700_,9.504635853,0.651404782,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,67651,DB06228,10047700,325,15587,150,15926,1.28491149786304e-16,2.213746296,1.816362077,2.708038733,9.47374438185977e-15,DB0622810047700_,32.29025217,0.794686237,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,67652,DB06637,10047700,102,6060,17,2002,0.007150461,1.982146158,1.175582652,3.543258854,0.027243058,DB0663710047700_,3.602956531,0.684180176,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dalfampridine,DB06637
,67654,DB14512,10047700,105,4739,35,2377,0.037228163,1.504669022,1.0139403,2.281251978,0.10001454,DB1451210047700_,2.302439708,0.408572955,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,mometasone furoate,DB14512
,67656,DB00343,10047895,216,8520,115,4980,0.453539092,1.097863307,0.869048019,1.392782205,0.621093833,DB0034310047895_,0.476273109,0.093365842,NA,10047895,Weight decreased,10022891,Investigations,Inv,diltiazem,DB00343
,67657,DB00413,10047895,53,2146,28,1179,0.906962633,1.039915133,0.642058269,1.71743708,0.95853111,DB0041310047895_,0.04235326,0.039139107,NA,10047895,Weight decreased,10022891,Investigations,Inv,pramipexole,DB00413
,67658,DB00584,10047895,40,2041,53,1821,0.073522257,0.67343904,0.432975833,1.040203425,0.167391298,DB0058410047895_,1.787421104,-0.3953578,NA,10047895,Weight decreased,10022891,Investigations,Inv,enalapril,DB00584
,67659,DB00656,10047895,223,11790,114,6505,0.528009203,1.079281896,0.855585171,1.367539111,0.685455295,DB0065610047895_,0.377671997,0.076295909,NA,10047895,Weight decreased,10022891,Investigations,Inv,trazodone,DB00656
,67661,DB01097,10047895,98,6167,34,1469,0.074391853,0.68662378,0.458393354,1.050877496,0.168830069,DB0109710047895_,1.778862581,-0.375968764,NA,10047895,Weight decreased,10022891,Investigations,Inv,leflunomide,DB01097
,67663,DB06228,10047895,182,15730,140,15936,0.015910849,1.317009063,1.049556801,1.655420259,0.051616522,DB0622810047895_,2.963913456,0.275363304,NA,10047895,Weight decreased,10022891,Investigations,Inv,rivaroxaban,DB06228
,67664,DB06637,10047895,42,6120,26,1993,0.015363043,0.526130084,0.314225488,0.896265259,0.050238999,DB0663710047895_,2.990963691,-0.64220679,NA,10047895,Weight decreased,10022891,Investigations,Inv,dalfampridine,DB06637
,67666,DB00153,10049848,44,7379,28,3411,0.203650114,0.726409225,0.441398936,1.213882574,0.353434567,DB0015310049848_,1.040056911,-0.319641752,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,67669,DB00341,10049848,78,11327,27,5041,0.289581363,1.285625202,0.819308452,2.074992851,0.454725261,DB0034110049848_,0.788061865,0.251245138,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,67670,DB00343,10049848,47,8689,33,5062,0.417585091,0.829749079,0.519718274,1.33874915,0.586665817,DB0034310049848_,0.533299927,-0.186631939,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,67671,DB00381,10049848,217,29143,118,22769,0.001602804,1.436758694,1.142193858,1.81474939,0.008108102,DB0038110049848_,4.814891492,0.36238967,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,67673,DB00421,10049848,42,8861,29,5223,0.538893939,0.85368274,0.5186598,1.422933637,0.694779997,DB0042110049848_,0.364160034,-0.158195653,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,67674,DB00476,10049848,168,17089,68,6109,0.413935982,0.883206473,0.661483594,1.190398018,0.583253761,DB0047610049848_,0.53913292,-0.124196275,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,67676,DB00586,10049848,56,7053,18,2787,0.517914104,1.229320739,0.710440351,2.226209169,0.677380677,DB0058610049848_,0.389521865,0.206461772,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,67677,DB00635,10049848,146,32907,80,23714,0.050159217,1.315155349,0.994041322,1.750655539,0.125320566,DB0063510049848_,2.0768803,0.273954795,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,67678,DB00656,10049848,116,11897,53,6566,0.293839351,1.207893855,0.864259034,1.7074005,0.459570457,DB0065610049848_,0.777463015,0.188878227,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,67681,DB00924,10049848,80,10082,29,4222,0.598107058,1.15519954,0.745569647,1.835865675,0.742999711,DB0092410049848_,0.297059623,0.144273091,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,67684,DB01592,10049848,43,6233,29,3038,0.207164709,0.722707937,0.439986941,1.202930188,0.357839551,DB0159210049848_,1.027670574,-0.324750099,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,iron,DB01592
,67685,DB06228,10049848,53,15859,38,16038,0.11540899,1.410457674,0.911921563,2.200357002,0.234285241,DB0622810049848_,1.451215929,0.343914243,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,67686,DB06637,10049848,247,5915,70,1949,0.288324825,1.16264414,0.883549244,1.546383509,0.453307296,DB0663710049848_,0.791185027,0.150696842,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,67690,DB00005,10050324,54,128028,30,42389,0.030856895,0.595967286,0.374555971,0.96482086,0.086602263,DB0000510050324_,2.446429333,-0.517569503,NA,10050324,Rotator cuff repair,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,67722,DB00230,10050584,153,19521,42,8609,0.006163216,1.606520209,1.134064264,2.319892449,0.024177319,DB0023010050584_,3.722340329,0.474070479,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,67724,DB00343,10050584,95,8641,26,5069,0.000302005,2.14331845,1.374511831,3.45185667,0.002028675,DB0034310050584_,6.200372221,0.762355306,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,67725,DB00381,10050584,240,29120,118,22769,2.89676486651048e-05,1.590293491,1.269655926,2.001071038,0.000275028,DB0038110050584_,8.198638137,0.463918585,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,67727,DB00421,10050584,87,8816,27,5225,0.002480239,1.909640902,1.22575291,3.064342794,0.011595034,DB0042110050584_,4.457178411,0.646915215,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,spironolactone,DB00421
,67728,DB00656,10050584,100,11913,35,6584,0.018923339,1.579030908,1.063363053,2.394514807,0.059157939,DB0065610050584_,2.827544473,0.456811309,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,67731,DB00956,10050584,56,5758,18,3449,0.021458118,1.86341717,1.077085177,3.373930106,0.065352717,DB0095610050584_,2.727956269,0.62241199,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocodone,DB00956
,67732,DB01068,10050584,118,13645,23,6817,8.67659875853777e-06,2.563048401,1.627727016,4.204105918,9.59463182028461e-05,DB0106810050584_,9.251721708,0.941197332,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,67733,DB01097,10050584,55,6210,11,1492,0.75390898,1.201260005,0.61998169,2.551571477,0.861624311,DB0109710050584_,0.148935938,0.18337101,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,leflunomide,DB01097
,67735,DB01373,10050584,249,22471,38,7343,3.23298391359339e-06,2.141336814,1.515767674,3.100630046,4.04276794333027e-05,DB0137310050584_,10.11599587,0.761430314,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,67736,DB01592,10050584,67,6209,32,3035,1,1.023455851,0.66051955,1.615758772,1,DB0159210050584_,0,0.023184989,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,iron,DB01592
,67737,DB06637,10050584,59,6103,9,2010,0.032891758,2.159016081,1.061035103,4.961865279,0.091050405,DB0663710050584_,2.396342028,0.7696526,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,dalfampridine,DB06637
,67800,DB00005,10057668,51,128031,19,42400,0.678456584,0.888916035,0.51578579,1.594468613,0.805257441,DB0000510057668_,0.21659325,-0.117752497,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,67802,DB00230,10057668,119,19555,55,8596,0.741974257,0.951095111,0.684576549,1.335621097,0.852096878,DB0023010057668_,0.160055052,-0.050141209,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,67807,DB00381,10057668,57,29303,46,22841,0.920888947,0.965858641,0.6432248,1.457433262,0.964941435,DB0038110057668_,0.035687869,-0.03473779,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,67810,DB00451,10057668,147,47124,48,15371,1,0.998928233,0.716256402,1.414977338,1,DB0045110057668_,0,-0.001072342,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,67811,DB00476,10057668,98,17159,37,6140,0.769372927,0.947763601,0.642376819,1.425136128,0.873675525,DB0047610057668_,0.135046225,-0.053650174,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,67814,DB00635,10057668,58,32995,32,23762,0.240825183,1.305300819,0.833391948,2.077947605,0.398846319,DB0063510057668_,0.919179102,0.266433527,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,67815,DB00656,10057668,55,11958,26,6593,0.562217874,1.166281507,0.718241679,1.939608337,0.714477569,DB0065610057668_,0.336203675,0.153820488,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,67817,DB00695,10057668,64,27985,41,20487,0.553436158,1.142709247,0.759910076,1.735727913,0.707011279,DB0069510057668_,0.346708661,0.133401975,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,67821,DB01068,10057668,76,13687,46,6794,0.290095294,0.820135604,0.560630296,1.211275961,0.455303111,DB0106810057668_,0.786791904,-0.198285582,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,67826,DB06637,10057668,54,6108,13,2006,0.393086366,1.36414579,0.732804461,2.730819295,0.563051423,DB0663710057668_,0.574384318,0.310528438,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,68027,DB00451,10062544,63,47208,7,15412,0.003220119,2.938306142,1.345216017,7.606942196,0.014331328,DB0045110062544_,4.245307349,1.077833273,female,10062544,Tooth fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,68041,DB01373,10062544,62,22658,14,7367,0.232633319,1.439858811,0.796541293,2.787051507,0.389103836,DB0137310062544_,0.94390904,0.364545061,NA,10062544,Tooth fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,68079,DB00005,10052438,110,127972,35,42384,0.923478814,1.040930629,0.70565238,1.569782858,0.966653683,DB0000510052438_,0.033914983,0.040115149,NA,10052438,Paranasal sinus discomfort,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,68080,DB00956,10013946,45,5769,12,3455,0.012685627,2.245664193,1.166309415,4.671157609,0.043024738,DB0095610013946_,3.145980035,0.809001332,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,hydrocodone,DB00956
,68081,DB00904,10017885,177,22892,83,14373,0.029593198,1.338922817,1.025019309,1.760993261,0.08382082,DB0090410017885_,2.479073852,0.291865423,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,68082,DB00956,10017885,42,5772,20,3447,0.432512511,1.254097928,0.718667824,2.258737622,0.600924563,DB0095610017885_,0.509285872,0.226416532,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,hydrocodone,DB00956
,68084,DB00904,10060795,76,22993,37,14419,0.24520294,1.288079315,0.858156824,1.964278816,0.40399657,DB0090410060795_,0.906348892,0.253152205,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,ondansetron,DB00904
,68091,DB01229,10001760,80,5661,24,2685,0.056459863,1.580914376,0.988541477,2.615746364,0.136892123,DB0122910001760_,1.988562088,0.458003399,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,paclitaxel,DB01229
,68094,DB01229,10002855,72,5669,7,2702,1.36582041594409e-06,4.902284817,2.256849645,12.64339457,1.89499021552338e-05,DB0122910002855_,10.87371179,1.589701386,female,10002855,Anxiety,10037175,Psychiatric disorders,Psych,paclitaxel,DB01229
,68097,DB01068,10027599,173,13590,32,6808,1.48867885763323e-08,2.708185367,1.846746352,4.087481173,3.21131914426667e-07,DB0106810027599_,14.95141385,0.996278804,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,68105,DB01068,10062519,43,13720,26,6814,0.44340174,0.821401673,0.492912587,1.393722707,0.611550514,DB0106810062519_,0.491757721,-0.196743041,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,68117,DB00335,10019301,34,8432,22,5443,1,0.997617356,0.566085853,1.792480751,1,DB0033510019301_,0,-0.002385487,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,atenolol,DB00335
,68118,DB00381,10019301,84,29276,56,22831,0.394127394,1.169769336,0.823958748,1.671780103,0.564066131,DB0038110019301_,0.572583781,0.156806581,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,amlodipine,DB00381
,68119,DB00678,10019301,36,15563,34,10690,0.182834567,0.72731195,0.442045168,1.198939137,0.327460248,DB0067810019301_,1.116388612,-0.318399802,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,losartan,DB00678
,68120,DB00758,10019301,21,8279,34,10040,0.342939751,0.749037432,0.412770693,1.329453623,0.512285255,DB0075810019301_,0.668873669,-0.28896632,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,clopidogrel,DB00758
,68122,DB00758,10020772,119,8181,103,9971,0.011987377,1.408087271,1.070649018,1.854381588,0.041118125,DB0075810020772_,3.191306251,0.342232238,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,clopidogrel,DB00758
,68124,DB00758,10036018,30,8270,24,10050,0.133363211,1.518991439,0.857766444,2.717315143,0.260463796,DB0075810036018_,1.345291407,0.418046588,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,clopidogrel,DB00758
,68126,DB08931,10008479,409,6168,116,2330,0.007315242,1.33183159,1.074893681,1.660453105,0.027724192,DB0893110008479_,3.585449906,0.28655513,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,68127,DB08931,10012378,71,6506,34,2412,0.225270484,0.774196439,0.506051407,1.205348238,0.38013897,DB0893110012378_,0.967218382,-0.25592964,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,riociguat,DB08931
,68128,DB00682,10013578,54,19405,33,16331,0.161641667,1.377128165,0.876504742,2.193579113,0.299608717,DB0068210013578_,1.205277932,0.320000291,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,68129,DB08931,10013578,73,6504,25,2421,0.819365584,1.086908119,0.679938383,1.791508377,0.90370193,DB0893110013578_,0.101255697,0.083337077,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,68130,DB00682,10017885,137,19322,58,16306,6.6446924957899e-06,1.993297474,1.455053571,2.76096031,7.59042773801988e-05,DB0068210017885_,9.48603752,0.68979029,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,68135,DB08931,10022437,143,6434,67,2379,0.11650661,0.78918343,0.584019568,1.075535877,0.235894026,DB0893110022437_,1.444372616,-0.236756502,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,riociguat,DB08931
,68136,DB00682,10028391,136,19323,60,16304,1.95032699806797e-05,1.912463275,1.400445466,2.638337799,0.000195365,DB0068210028391_,8.540643067,0.648392084,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,68137,DB08931,10028391,74,6503,24,2422,0.647790061,1.148346718,0.714215245,1.908158198,0.782894007,DB0893110028391_,0.24475796,0.138323272,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,riociguat,DB08931
,68138,DB08931,10028836,70,6507,19,2427,0.233336779,1.374067672,0.816031315,2.422021839,0.389908279,DB0893110028836_,0.94184375,0.317775445,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,riociguat,DB08931
,68141,DB00421,10042772,153,8750,93,5159,0.841770649,0.969968455,0.742944236,1.272077191,0.919347717,DB0042110042772_,0.084090864,-0.030491729,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,68142,DB01592,10042772,46,6230,28,3039,0.384574031,0.801427382,0.489285789,1.334285118,0.55464306,DB0159210042772_,0.589430507,-0.221360914,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,iron,DB01592
,68143,DB00993,10000081,80,3169,44,1575,0.629419187,0.903662732,0.614578841,1.343782894,0.768465017,DB0099310000081_,0.263360239,-0.101299072,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,azathioprine,DB00993
,68147,DB00230,10007515,69,19605,53,8598,0.002945112,0.570990563,0.393003067,0.833602034,0.013301076,DB0023010007515_,4.319910322,-0.560382597,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,pregabalin,DB00230
,68150,DB08932,10003119,78,19365,39,6558,0.054574278,0.677315723,0.454993269,1.023052853,0.133589578,DB0893210003119_,2.012983032,-0.389617758,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,macitentan,DB08932
,68166,DB00343,10047899,164,8572,60,5035,0.001620312,1.605446409,1.184888031,2.200169959,0.008181713,DB0034310047899_,4.805853769,0.473401855,NA,10047899,Weight increased,10022891,Investigations,Inv,diltiazem,DB00343
,68172,DB01076,10000125,36,25711,21,25562,0.062667523,1.704323517,0.968163241,3.073670391,0.148420972,DB0107610000125_,1.907702638,0.533168268,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,68173,DB05676,10000125,41,47088,37,25292,0.023825589,0.595168865,0.372133622,0.954852764,0.070835743,DB0567610000125_,2.647391565,-0.518910106,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,68174,DB00051,10042458,37,25694,30,11390,0.016518949,0.54676858,0.328499455,0.916824119,0.053133748,DB0005110042458_,2.934943002,-0.603729637,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,adalimumab,DB00051
,68175,DB01076,10042458,74,25673,48,25535,0.023138771,1.533358857,1.051662827,2.254121061,0.069239822,DB0107610042458_,2.670179126,0.427460661,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,68176,DB05676,10042458,145,46984,86,25243,0.489632516,0.9058626,0.688687955,1.197562066,0.65297307,DB0567610042458_,0.426219391,-0.098867641,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,68178,DB00563,10001551,117,46529,105,15243,3.61518221840227e-13,0.365049509,0.277899178,0.480032765,1.71991067168694e-11,DB0056310001551_,24.78616367,-1.007722293,male,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,methotrexate,DB00563
,68179,DB00563,10003481,94,46552,71,15277,2.83037787575498e-07,0.434482433,0.315682791,0.600272542,4.64252620681558e-06,DB0056310003481_,12.2802519,-0.833599766,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,methotrexate,DB00563
,68181,DB00563,10013722,30,46616,24,15324,0.001468491,0.410915963,0.232159945,0.73469875,0.007556633,DB0056310013722_,4.885329519,-0.889366555,NA,10013722,Drug level increased,10022891,Investigations,Inv,methotrexate,DB00563
,68183,DB00650,10033661,37,2094,30,1984,0.540707305,1.168500363,0.69939495,1.966669372,0.696212967,DB0065010033661_,0.362099678,0.155721186,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,leucovorin,DB00650
,68187,DB00650,10070863,44,2087,42,1972,1,0.989893581,0.630613172,1.555710933,1,DB0065010070863_,0,-0.010157836,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,leucovorin,DB00650
,68224,DB00472,10045555,65,10694,25,4287,0.907430706,1.04225716,0.647031508,1.728235855,0.958745315,DB0047210045555_,0.042129813,0.041388708,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,68225,DB01224,10045555,63,8045,70,5847,0.016957532,0.654141401,0.457103651,0.934442546,0.054277731,DB0122410045555_,2.913641244,-0.424431741,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,68227,DB00215,10046543,31,11072,19,5257,0.367778639,0.774716943,0.423568692,1.452841677,0.537462071,DB0021510046543_,0.620897087,-0.255257551,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,citalopram,DB00215
,68229,DB00338,10046543,92,33582,39,22233,0.01994312,1.561748203,1.06248859,2.334463123,0.061620418,DB0033810046543_,2.786761996,0.445805837,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,68231,DB00451,10046543,127,47144,28,15391,0.061696641,1.480723933,0.97691054,2.317490777,0.146554265,DB0045110046543_,1.920359512,0.392531112,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,68233,DB00472,10046543,43,10716,12,4300,0.298137988,1.43778749,0.743968451,2.998369001,0.464045825,DB0047210046543_,0.767771972,0.363105467,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,fluoxetine,DB00472
,68253,DB00996,10058046,44,38909,20,22405,0.436704857,1.266848826,0.730913238,2.269512469,0.605245691,DB0099610058046_,0.502120802,0.236532578,NA,10058046,Post procedural complication,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,68268,DB00193,10007515,164,19156,83,8619,0.407209763,0.88904289,0.677752439,1.173593146,0.576751739,DB0019310007515_,0.550343367,-0.117609799,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,tramadol,DB00193
,68269,DB00683,10007515,56,1528,71,1567,0.277197657,0.808918251,0.555305855,1.173529257,0.440742849,DB0068310007515_,0.819293683,-0.212057416,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,midazolam,DB00683
,68270,DB00813,10007515,285,10287,371,9797,9.8073315620564e-05,0.731617503,0.623151653,0.858242159,0.000783781,DB0081310007515_,7.151380373,-0.312497438,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,fentanyl,DB00813
,68271,DB01104,10007515,187,15276,97,7189,0.442908427,0.907260988,0.705001506,1.173676009,0.610982041,DB0110410007515_,0.492687714,-0.097325122,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,sertraline,DB01104
,68273,DB00813,10010071,70,10502,55,10113,0.281923181,1.225570932,0.847662149,1.779730058,0.445887603,DB0081310010071_,0.807688369,0.203406803,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,68279,DB00193,10024855,134,19186,56,8646,0.694228086,1.078315688,0.782922429,1.502200165,0.815926368,DB0019310024855_,0.203431164,0.075400276,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,68281,DB00813,10024855,80,10492,79,10089,0.873842748,0.973757444,0.703665137,1.347818984,0.945166209,DB0081310024855_,0.056394484,-0.026593037,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,68282,DB00683,10040108,21,1563,98,1540,4.29407369064243e-13,0.211236492,0.12450692,0.343111951,2.01553083854529e-11,DB0068310040108_,24.62755342,-1.55477696,male,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,midazolam,DB00683
,68290,DB00216,10028813,63,860,6,102,0.838168111,1.24510252,0.522715777,3.609363553,0.916822672,DB0021610028813_,0.086841204,0.219217872,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,eletriptan,DB00216
,68296,DB00722,10020993,88,25315,117,25915,0.068722127,0.769969295,0.576871857,1.024603316,0.159021355,DB0072210020993_,1.838716776,-0.261404642,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,68297,DB00999,10020993,46,21384,53,12186,0.000509567,0.494599605,0.325609664,0.74887391,0.003135693,DB0099910020993_,5.764905088,-0.704006722,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,68300,DB00999,10063743,53,21377,31,12208,0.910014357,0.97635124,0.614976846,1.574548326,0.959542868,DB0099910063743_,0.041298287,-0.02393288,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,68304,DB00264,10008111,61,29546,85,24807,0.002651863,0.602554097,0.426222692,0.847511109,0.012223449,DB0026410008111_,4.404399148,-0.50657783,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,68311,DB14726,10008111,26,1991,54,2794,0.109683743,0.67572309,0.40466421,1.102338729,0.225589765,DB1472610008111_,1.48903713,-0.391971917,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,dabigatran,DB14726
,68313,DB00404,10038687,34,19858,18,9844,0.882911378,0.936362423,0.513912575,1.761977156,0.951061434,DB0040410038687_,0.050176619,-0.065752673,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,68314,DB00588,10038687,67,16457,38,8430,0.606964576,0.903173927,0.597256913,1.383671841,0.749897244,DB0058810038687_,0.28781909,-0.101840134,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,68317,DB01050,10038687,35,18073,26,9345,0.176468578,0.696039676,0.40689348,1.204895738,0.319300376,DB0105010038687_,1.141623002,-0.362348614,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,68346,DB00051,10005483,30,25701,26,11394,0.013523787,0.511522771,0.292269537,0.900894194,0.045283153,DB0005110005483_,3.094820224,-0.670363176,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,adalimumab,DB00051
,68350,DB00695,10005851,81,27968,76,20452,0.124443931,0.779384791,0.562541202,1.080816356,0.247728621,DB0069510005851_,1.395421401,-0.2492504,NA,10005851,Blood urea increased,10022891,Investigations,Inv,furosemide,DB00695
,68351,DB00051,10016173,306,25425,115,11305,0.136837463,1.18311475,0.950640328,1.480798809,0.265284175,DB0005110016173_,1.326953669,0.16815058,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,68352,DB00051,10023230,169,25562,67,11353,0.479194435,1.120275789,0.838630483,1.511184599,0.644343448,DB0005110023230_,0.43952339,0.113574895,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,68355,DB00695,10023230,43,28006,20,20508,0.097911571,1.574366822,0.906004982,2.825929087,0.207741507,DB0069510023230_,1.571460729,0.453853174,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,68359,DB00437,10041349,65,6856,77,11469,0.045141735,1.412068162,0.997731418,1.993295135,0.115862758,DB0043710041349_,2.155348909,0.345055411,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,68365,DB00437,10062237,75,6846,87,11459,0.022313803,1.442874072,1.043594046,1.991039154,0.067323039,DB0043710062237_,2.698252767,0.366637008,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,allopurinol,DB00437
,68366,DB00695,10062237,187,27862,161,20367,0.141364198,0.849050589,0.683477924,1.055671795,0.271768728,DB0069510062237_,1.302803838,-0.163636508,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,68367,DB06674,10022095,52,4454,7,1483,0.021999187,2.473266069,1.11573099,6.468330134,0.06663002,DB0667410022095_,2.708600052,0.905539572,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,golimumab,DB06674
,68368,DB06674,10063829,228,4278,87,1403,0.254771225,0.859517276,0.663306393,1.121734709,0.415502987,DB0667410063829_,0.878265475,-0.151384354,NA,10063829,Device malfunction,10077536,Product issues,Prod,golimumab,DB06674
,68384,DB00051,10038435,66,25665,47,11373,0.01419036,0.622280072,0.42135616,0.925424756,0.047089208,DB0005110038435_,3.055711441,-0.474365011,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,adalimumab,DB00051
,68386,DB00381,10013538,106,29254,39,22848,3.41460634030569e-05,2.122719514,1.457094411,3.149285981,0.000317935,DB0038110013538_,8.053664967,0.752698056,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,amlodipine,DB00381
,68389,DB00264,10018627,73,29534,89,24803,0.021703714,0.688845953,0.498218154,0.949862247,0.065959314,DB0026410018627_,2.718717177,-0.372737614,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,68393,DB00264,10019194,43,29564,20,24872,0.03085609,1.808757194,1.040946558,3.246652107,0.086602263,DB0026410019194_,2.446429333,0.592639976,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,68395,DB00381,10019194,42,29318,16,22871,0.016392293,2.047715018,1.127067028,3.903089322,0.052802872,DB0038110019194_,2.941189698,0.716724546,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,68400,DB00381,10029216,103,29257,40,22847,0.00012923,2.01078826,1.382461767,2.975419155,0.000992491,DB0038110029216_,6.915292291,0.698526814,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,68403,DB01068,10029216,76,13687,36,6804,0.841331829,1.049460104,0.696255871,1.608457072,0.9190212,DB0106810029216_,0.084446088,0.048275846,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,68426,DB00641,10029331,145,13979,157,12318,0.08181112,0.813836476,0.643977912,1.027922655,0.181399914,DB0064110029331_,1.707051216,-0.205995823,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,68427,DB01098,10029331,79,8070,72,7137,0.870110231,0.970361866,0.694913828,1.356818151,0.942295438,DB0109810029331_,0.059436426,-0.030086219,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,68428,DB00482,10008469,44,8215,13,3058,0.551071754,1.259870544,0.665360128,2.553457758,0.705136845,DB0048210008469_,0.349363389,0.231008973,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,68449,DB00182,10022523,42,5152,39,2813,0.019285817,0.588015602,0.370154506,0.936074786,0.060093609,DB0018210022523_,2.811851778,-0.531001798,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,amphetamine,DB00182
,68471,DB01050,10013786,89,18019,36,9335,0.220350342,1.280801207,0.859775457,1.943987969,0.373876561,DB0105010013786_,0.983829587,0.247485825,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,68481,DB00455,10013971,71,9330,20,5098,0.007935152,1.939673426,1.165739953,3.368271525,0.029595318,DB0045510013971_,3.520139097,0.662519622,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,68482,DB00999,10013971,77,21353,37,12202,0.435555141,1.18918151,0.79301498,1.812137972,0.604018512,DB0099910013971_,0.504150432,0.173265264,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,68483,DB01050,10013971,57,18051,21,9350,0.190493208,1.405920635,0.838624692,2.443226202,0.337185534,DB0105010013971_,1.087121954,0.340692344,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,68496,DB00215,10033557,70,11033,21,5255,0.071314702,1.587620249,0.961988485,2.725899024,0.163562406,DB0021510033557_,1.810560676,0.462236197,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,citalopram,DB00215
,68497,DB00381,10033557,268,29092,79,22808,3.25248483022248e-16,2.65952792,2.060830345,3.465084498,2.30125339871865e-14,DB0038110033557_,31.40273737,0.978148633,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,amlodipine,DB00381
,68499,DB00455,10033557,89,9312,19,5099,6.73007651080195e-05,2.564799267,1.548005482,4.464091598,0.000567847,DB0045510033557_,7.473658932,0.941880217,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,loratadine,DB00455
,68519,DB00285,10046735,92,10859,14,3704,0.003322711,2.241530293,1.268413183,4.265552288,0.014692238,DB0028510046735_,4.220435925,0.807158799,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,venlafaxine,DB00285
,68536,DB00230,10016970,78,19596,20,8631,0.028108334,1.717714131,1.039551878,2.966886658,0.080473538,DB0023010016970_,2.519826872,0.540994413,NA,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,68545,DB00996,10016970,88,38865,34,22391,0.048207713,1.491130983,0.992887914,2.286184559,0.121735012,DB0099610016970_,2.105908629,0.399534881,NA,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,68561,DB00230,10024453,43,19631,10,8641,0.072938127,1.892698799,0.935989555,4.226074922,0.16642176,DB0023010024453_,1.793229989,0.638003746,NA,10024453,Ligament sprain,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,68575,DB00230,10039117,49,19625,26,8625,0.452093582,0.828295881,0.504419993,1.389429241,0.619663127,DB0023010039117_,0.478579292,-0.188384844,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,68589,DB00230,10039203,122,19552,45,8606,0.354002044,1.193301513,0.840448736,1.720954797,0.523868018,DB0023010039203_,0.646515501,0.176723847,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,68591,DB00273,10039203,46,8435,10,2183,0.740806794,1.190471927,0.591363263,2.650138971,0.851258239,DB0027310039203_,0.161039743,0.174349806,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,topiramate,DB00273
,68596,DB00829,10039203,30,8022,24,4430,0.199741037,0.690340441,0.389611055,1.235483287,0.348768934,DB0082910039203_,1.053345656,-0.370570411,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,68600,DB00996,10039203,112,38841,45,22380,0.046056738,1.434077724,1.005762419,2.075421503,0.117579773,DB0099610039203_,2.140638253,0.360521941,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,68626,DB00996,10060820,89,38864,22,22403,0.000159496,2.331954196,1.448801159,3.908084969,0.001189044,DB0099610060820_,6.7346054,0.846706627,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,68630,DB00230,10061599,72,19602,27,8624,0.513763854,1.173197766,0.743792137,1.901124481,0.673715129,DB0023010061599_,0.394947914,0.159733154,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,68639,DB00996,10061599,66,38887,21,22404,0.018749595,1.810679337,1.093470491,3.116957091,0.05872304,DB0099610061599_,2.834923133,0.593702099,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,68646,DB00275,10020772,59,2001,24,1213,0.108650474,1.490062995,0.907214095,2.518530639,0.224007977,DB0027510020772_,1.496073615,0.398818397,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,olmesartan,DB00275
,68649,DB00999,10023547,100,21330,52,12187,0.612914858,1.098768375,0.777683978,1.568429144,0.754720666,DB0099910023547_,0.281407578,0.094189893,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,68650,DB01050,10023547,76,18032,41,9330,0.845280008,0.959122867,0.647120809,1.439760138,0.921992904,DB0105010023547_,0.081217752,-0.041736093,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,ibuprofen,DB01050
,68652,DB00275,10033371,71,1989,29,1208,0.075470329,1.486766808,0.946399966,2.390372492,0.170592325,DB0027510033371_,1.768478636,0.396603835,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,olmesartan,DB00275
,68653,DB08877,10033371,88,3201,61,3168,0.038015475,1.427666599,1.01429595,2.020587677,0.101656926,DB0887710033371_,2.286151608,0.356041363,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,68655,DB00999,10047943,62,21368,32,12207,0.669229068,1.10685524,0.710853019,1.753870782,0.79917165,DB0099910047943_,0.224179526,0.101522878,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,68656,DB01050,10047943,46,18062,28,9343,0.53948451,0.849821374,0.51965046,1.412880778,0.695302672,DB0105010047943_,0.363408028,-0.162729099,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,ibuprofen,DB01050
,68658,DB01050,10049414,34,18074,35,9336,0.004855367,0.501783512,0.303444939,0.829032457,0.019989554,DB0105010049414_,3.912545424,-0.689586503,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,68664,DB08877,10051608,125,3164,72,3157,0.000213186,1.732115311,1.280132654,2.358525849,0.001519617,DB0887710051608_,6.489297274,0.549343385,NA,10051608,Platelet count increased,10022891,Investigations,Inv,ruxolitinib,DB08877
,68665,DB00169,10051608,61,38630,19,18156,0.120328223,1.508928897,0.888933744,2.675471414,0.241806371,DB0016910051608_,1.419617992,0.41140006,NA,10051608,Platelet count increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,68666,DB08896,10000081,61,762,63,977,0.261851967,1.241296352,0.846974063,1.818285989,0.423516535,DB0889610000081_,0.859162723,0.216156278,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,regorafenib,DB08896
,68671,DB08827,10053762,38,1124,34,548,0.014762483,0.545082307,0.330049778,0.903448286,0.048698779,DB0882710053762_,3.022101312,-0.606818474,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lomitapide,DB08827
,68672,DB00108,10061024,35,10159,17,3278,0.194221982,0.664342137,0.361778339,1.266324516,0.34201754,DB0010810061024_,1.072893257,-0.408957996,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,natalizumab,DB00108
,68679,DB09140,10012378,49,3692,16,1782,0.185400854,1.478065442,0.823514713,2.792678508,0.330695538,DB0914010012378_,1.106557152,0.390734099,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,oxygen,DB09140
,68681,DB09140,10024855,90,3651,31,1767,0.116206842,1.405013442,0.92070394,2.196027924,0.235450307,DB0914010024855_,1.446255398,0.34004687,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,oxygen,DB09140
,68690,DB00820,10033557,419,11496,82,5734,4.52160902323501e-17,2.548536495,2.002438827,3.27686425,3.49046969679096e-15,DB0082010033557_,33.28874008,0.935519271,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,tadalafil,DB00820
,68692,DB09140,10033557,160,3581,25,1773,3.08170234057515e-09,3.168202626,2.060679664,5.061982258,7.76630354957025e-08,DB0914010033557_,16.37088643,1.153164432,female,10033557,Palpitations,10007541,Cardiac disorders,Card,oxygen,DB09140
,68693,DB08906,10013709,112,2081,47,1111,0.199861049,1.27215261,0.889609587,1.843409227,0.348819311,DB0890610013709_,1.053201224,0.240710434,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fluticasone furoate,DB08906
,68696,DB08906,10053762,57,2136,20,1138,0.116148636,1.518222346,0.893029245,2.681969651,0.235359589,DB0890610053762_,1.446640769,0.417540141,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone furoate,DB08906
,68698,DB08868,10027175,274,8928,72,2439,0.84187956,1.039636922,0.795882116,1.372633313,0.919428463,DB0886810027175_,0.084003038,0.038871538,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,68699,DB08868,10041349,114,9088,33,2478,0.761753603,0.941939387,0.632666218,1.436934193,0.867966655,DB0886810041349_,0.141601982,-0.059814352,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,68700,DB01156,10000081,171,13451,42,6286,0.000108418,1.902629756,1.348767229,2.738002836,0.00085476,DB0115610000081_,7.064689534,0.643237012,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,68702,DB06637,10000081,37,6125,13,2006,0.869308352,0.932145754,0.483106791,1.915137743,0.941838249,DB0663710000081_,0.059921729,-0.070266088,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,dalfampridine,DB06637
,68703,DB08868,10000081,88,9114,27,2484,0.569351039,0.888294264,0.569986481,1.425979508,0.720261201,DB0886810000081_,0.328141353,-0.118452213,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,fingolimod,DB08868
,68704,DB01156,10001551,46,13576,25,6303,0.524787747,0.854284819,0.513486522,1.45236869,0.682936506,DB0115610001551_,0.381353387,-0.15749063,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,bupropion,DB01156
,68707,DB01156,10003481,46,13576,26,6302,0.447013113,0.821306679,0.496616204,1.385380062,0.614783366,DB0115610003481_,0.486485324,-0.196858696,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,bupropion,DB01156
,68711,DB08868,10008479,166,9036,31,2480,0.053676807,1.469615018,0.993993944,2.238044533,0.13188736,DB0886810008479_,2.025807054,0.385000474,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,68712,DB06413,10013968,53,1503,17,657,0.293207333,1.362668473,0.769615262,2.530452891,0.458815583,DB0641310013968_,0.77910693,0.30944489,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,armodafinil,DB06413
,68717,DB01076,10025256,37,25710,26,25557,0.207235017,1.414592675,0.833556875,2.433787479,0.357923609,DB0107610025256_,1.027435699,0.346841628,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,68720,DB06637,10025256,82,6080,22,1997,0.49199157,1.224201981,0.754676,2.064746316,0.65501299,DB0663710025256_,0.423100211,0.202289187,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,dalfampridine,DB06637
,68721,DB01076,10034474,51,25696,58,25525,0.503103246,0.873461691,0.587347016,1.295494265,0.664263267,DB0107610034474_,0.409076722,-0.135291007,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,68726,DB01156,10047942,77,13545,30,6298,0.466359833,1.193393695,0.772460533,1.887505656,0.633093464,DB0115610047942_,0.457137215,0.176801093,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,bupropion,DB01156
,68728,DB01076,10059570,47,25700,55,25528,0.428993862,0.848829971,0.562363868,1.276688764,0.597504433,DB0107610059570_,0.514993575,-0.163896382,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,atorvastatin,DB01076
,68733,DB01076,10022611,40,25707,35,25548,0.644348328,1.135785,0.703173541,1.842295156,0.780474911,DB0107610022611_,0.247852684,0.127324042,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,68742,DB00559,10053762,73,9586,49,3257,0.000351937,0.506189227,0.34688325,0.744255642,0.00230374,DB0055910053762_,6.073221412,-0.680844713,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,bosentan,DB00559
,68745,DB00813,10055798,21,10551,34,10134,0.059708039,0.593255286,0.326942906,1.052811545,0.142928447,DB0081310055798_,1.945411144,-0.522130473,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,fentanyl,DB00813
,68748,DB00404,10013654,827,19065,1656,8206,3.7655810093745e-280,0.214962594,0.196737684,0.234757444,6.59855312209392e-276,DB0040410013654_,633.6266353,-1.537291248,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,68749,DB00555,10013654,38,7009,55,3431,3.19925660575541e-07,0.338247301,0.217194046,0.521911029,5.17332881465893e-06,DB0055510013654_,12.17199421,-1.083977992,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,68750,DB00557,10013654,126,5861,108,2959,8.35963953214435e-05,0.589024031,0.450083098,0.77193814,0.000684527,DB0055710013654_,7.28678266,-0.529288296,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,hydroxyzine,DB00557
,68752,DB00555,10017577,132,6915,58,3428,0.484187705,1.128202266,0.820051588,1.568512982,0.648383046,DB0055510017577_,0.433273637,0.120625451,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,68753,DB00557,10017577,86,5901,27,3040,0.027309892,1.640819699,1.051355198,2.637053167,0.078680386,DB0055710017577_,2.542361382,0.495195934,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,68754,DB01224,10017577,112,7996,78,5839,0.767879393,1.048553618,0.77671899,1.421458221,0.872620399,DB0122410017577_,0.136254641,0.047411708,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,68756,DB00404,10022523,144,19748,52,9810,0.048056985,1.375641919,0.994300516,1.929055708,0.121447731,DB0040410022523_,2.108271308,0.318920473,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,68757,DB00557,10022523,52,5935,58,3009,4.36876836732857e-05,0.454580506,0.305688543,0.674512651,0.000394141,DB0055710022523_,7.838801007,-0.788380249,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxyzine,DB00557
,68759,DB00555,10040108,81,6966,21,3465,0.005932053,1.918499728,1.173110731,3.270875512,0.023454273,DB0055510040108_,3.752702565,0.651543489,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,68765,DB00404,10041349,283,19609,110,9752,0.03083157,1.279512796,1.021583229,1.611804932,0.086558913,DB0040410041349_,2.446930022,0.246479377,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,68766,DB00557,10041349,116,5871,36,3031,0.007231806,1.663439349,1.132412896,2.496552137,0.027467525,DB0055710041349_,3.594750869,0.508887356,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,68768,DB00557,10042458,95,5892,29,3038,0.012812459,1.688992361,1.101261264,2.662324277,0.043390516,DB0055710042458_,3.137514395,0.524132115,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,hydroxyzine,DB00557
,68769,DB00404,10042464,121,19771,34,9828,0.00265354,1.769030794,1.199532539,2.672362108,0.012230107,DB0040410042464_,4.403854576,0.570431822,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,68770,DB00557,10042464,55,5932,27,3040,0.907122373,1.043927041,0.645842898,1.725075821,0.958618244,DB0055710042464_,0.042262361,0.042989603,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,hydroxyzine,DB00557
,68774,DB00996,10022061,245,38708,46,22379,7.88213896654229e-15,3.0792162,2.238679828,4.31837028,4.70868233489918e-13,DB0099610022061_,28.3841981,1.124675084,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,68775,DB01068,10022061,86,13677,9,6831,8.18013501737221e-08,4.772836475,2.398328982,10.79626757,1.50781801494831e-06,DB0106810022061_,13.40484698,1.562940777,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,68780,DB05259,10022079,63,11207,17,2711,0.67177492,0.896448733,0.517092993,1.636943456,0.800822342,DB0525910022079_,0.222116152,-0.109314173,NA,10022079,Injection site irritation,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,68782,DB00996,10022093,140,38813,23,22402,2.58016479787447e-10,3.513191135,2.249032084,5.725945231,7.90438598043479e-09,DB0099610022093_,18.65584804,1.25652478,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,68783,DB01068,10022093,52,13711,6,6834,0.000113518,4.318970575,1.854878648,12.3136645,0.000889894,DB0106810022093_,7.024407658,1.463017081,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,68785,DB00996,10022095,251,38702,59,22366,2.06846095974338e-11,2.458500177,1.843967579,3.324475315,7.49407254677529e-10,DB0099610022095_,21.01173855,0.89955148,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,68786,DB01068,10022095,82,13681,22,6818,0.008787345,1.857456414,1.147485026,3.12667919,0.032099974,DB0106810022095_,3.438900062,0.619208033,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,68788,DB00588,10053425,61,16463,14,8454,0.004701341,2.237396015,1.236284371,4.334269719,0.019463654,DB0058810053425_,3.939206468,0.805312696,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,68789,DB00996,10053425,143,38810,18,22407,4.2612219950764e-13,4.586428897,2.799281619,7.961256401,2.00199354403883e-11,DB0099610053425_,24.63429257,1.523101703,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,68790,DB01068,10053425,60,13703,12,6828,0.002394009,2.491332811,1.325543003,5.09121987,0.011267062,DB0106810053425_,4.485871719,0.912817833,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,68800,DB05259,10067142,82,11188,24,2704,0.390748294,0.825777763,0.517415299,1.363951661,0.56061892,DB0525910067142_,0.578713892,-0.191429594,NA,10067142,Immediate post-injection reaction,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,68802,DB08875,10037377,18,625,43,1200,0.494239733,0.803781866,0.432519123,1.437396672,0.656804057,DB0887510037377_,0.420369543,-0.218427357,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cabozantinib,DB08875
,68816,DB00152,10035664,32,799,42,822,0.342282466,0.78395094,0.473794968,1.286251408,0.511604431,DB0015210035664_,0.670203549,-0.243408838,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,thiamine,DB00152
,68818,DB11365,10035664,92,1553,100,1448,0.332992434,0.8578403,0.633179742,1.161167182,0.502004882,DB1136510035664_,0.689145434,-0.153337327,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sennosides,DB11365
,68845,DB01060,10011224,172,8415,106,4975,0.7540656,0.959342659,0.7467573,1.237117178,0.861728372,DB0106010011224_,0.148815172,-0.041506959,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amoxicillin,DB01060
,68846,DB01413,10011224,28,1192,38,1621,1,1.002030444,0.588666601,1.687022882,1,DB0141310011224_,0,0.002028386,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cefepime,DB01413
,68848,DB08934,10011224,39,4450,53,6151,1,1.017128332,0.653674718,1.570455579,1,DB0893410011224_,0,0.016983295,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sofosbuvir,DB08934
,68849,DB01413,10012735,39,1181,38,1621,0.160397008,1.408492984,0.871657467,2.277763616,0.29803177,DB0141310012735_,1.210555189,0.342520327,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cefepime,DB01413
,68852,DB00904,10013990,87,22982,41,14415,0.145498654,1.330941526,0.907506298,1.980583147,0.277746623,DB0090410013990_,1.281046008,0.285886606,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,ondansetron,DB00904
,68859,DB01033,10016256,47,1135,53,1251,0.919043038,0.977430781,0.640046422,1.48866438,0.964256911,DB0103310016256_,0.036397515,-0.022827802,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,mercaptopurine,DB01033
,68860,DB01413,10016256,34,1186,34,1625,0.21507772,1.369980543,0.820948722,2.286048693,0.36750425,DB0141310016256_,1.001020397,0.314796538,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cefepime,DB01413
,68868,DB01033,10028813,77,1105,84,1220,1,1.012063002,0.724919384,1.41136545,1,DB0103310028813_,0,0.011990823,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,mercaptopurine,DB01033
,68869,DB01413,10028813,51,1169,30,1629,0.000218685,2.368245929,1.469681293,3.876759516,0.001553549,DB0141310028813_,6.467213324,0.862149567,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cefepime,DB01413
,68872,DB01060,10030124,57,8530,44,5037,0.181041447,0.765002781,0.506343573,1.162577603,0.325161405,DB0106010030124_,1.123433588,-0.26787581,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,68877,DB01033,10043071,33,1149,23,1281,0.103776779,1.59929723,0.905110484,2.870691869,0.21667045,DB0103310043071_,1.529377745,0.469564301,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,mercaptopurine,DB01033
,68878,DB01060,10043071,41,8546,38,5043,0.047404125,0.63673661,0.398835598,1.018738562,0.120224081,DB0106010043071_,2.118397933,-0.451399194,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,amoxicillin,DB01060
,68879,DB01413,10043071,28,1192,31,1628,0.427901965,1.233501387,0.70875211,2.138112854,0.596394462,DB0141310043071_,0.516852981,0.209856781,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,cefepime,DB01413
,68883,DB01060,10046571,151,8436,46,5035,3.93318290172318e-05,1.959124572,1.397072767,2.793323662,0.000359596,DB0106010046571_,7.930530708,0.672497727,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,68886,DB01413,10053762,42,1178,64,1595,0.616911419,0.888618207,0.582852014,1.34249313,0.758040539,DB0141310053762_,0.277018414,-0.118087599,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cefepime,DB01413
,68903,DB01202,10013573,167,6547,116,5602,0.091292118,1.231832321,0.963481141,1.579283972,0.197336623,DB0120210013573_,1.622844264,0.208502752,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,68904,DB11093,10013573,58,1599,20,640,0.612234605,1.16064599,0.681186551,2.054878323,0.754133308,DB1109310013573_,0.282186126,0.148976738,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,calcium citrate,DB11093
,68924,DB01098,10042772,70,8079,70,7139,0.496544712,0.883656922,0.624261772,1.250811716,0.658693268,DB0109810042772_,0.417497303,-0.123686389,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,68925,DB01098,10060795,56,8093,42,7167,0.477454368,1.180760023,0.77629714,1.808209796,0.642759952,DB0109810060795_,0.441983949,0.166158318,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,rosuvastatin,DB01098
,68926,DB01065,10011906,140,4191,162,2889,1.21804870741071e-05,0.595780574,0.469320161,0.755530249,0.000129072,DB0106510011906_,8.955137025,-0.517882844,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,68927,DB09153,10011906,193,7606,210,5489,5.07260578686025e-05,0.663280577,0.540935749,0.812886799,0.000447503,DB0915310011906_,7.711827884,-0.410557185,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,68935,DB00177,10003658,49,4751,42,2808,0.081500436,0.689597991,0.446000286,1.070289243,0.18087124,DB0017710003658_,1.70996988,-0.371646472,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,valsartan,DB00177
,68937,DB00005,10066371,33,128049,19,42400,0.055407079,0.57511144,0.317521451,1.070620255,0.135014499,DB0000510066371_,2.002373103,-0.553191449,NA,10066371,Tendon pain,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,68938,DB00381,10003246,175,29185,69,22818,7.27194951234581e-07,1.982881541,1.491714628,2.661091338,1.08021018893478e-05,DB0038110003246_,11.43576982,0.684551111,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,68941,DB00169,10023469,85,38606,12,18163,1.00355182070248e-05,3.332307468,1.81124095,6.7044369,0.000108934,DB0016910023469_,9.124768686,1.203664997,female,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,cholecalciferol,DB00169
,68943,DB00722,10023469,43,25360,24,26008,0.019529434,1.837413643,1.089954144,3.166836892,0.060688204,DB0072210023469_,2.802005935,0.608358954,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,lisinopril,DB00722
,68945,DB00169,10029174,41,38650,11,18164,0.102830242,1.751657842,0.883997664,3.779316644,0.215241324,DB0016910029174_,1.535995445,0.560562678,NA,10029174,Nerve compression,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,68977,DB00335,10017577,131,8335,66,5399,0.105898574,1.285659495,0.9472382,1.759128739,0.220025612,DB0033510017577_,1.51401132,0.251271813,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,68979,DB00654,10012174,32,3784,23,2575,0.890572952,0.946800579,0.535561495,1.698590189,0.954671384,DB0065410012174_,0.046388098,-0.05466679,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,latanoprost,DB00654
,68980,DB00741,10012174,72,4022,72,3102,0.127128298,0.771292222,0.546589659,1.088367304,0.251624044,DB0074110012174_,1.379819195,-0.259687961,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,hydrocortisone,DB00741
,68981,DB01240,10012174,159,5592,23,1553,0.002463271,1.919666787,1.229793878,3.127506919,0.011532119,DB0124010012174_,4.462619149,0.652151623,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,epoprostenol,DB01240
,68999,DB00695,10012587,47,28002,8,20520,1.4251623820159e-05,4.305095677,2.014952622,10.55280438,0.000148417,DB0069510012587_,8.815486216,1.459799362,female,10012587,Device leakage,10077536,Product issues,Prod,furosemide,DB00695
,69005,DB00654,10012735,151,3665,93,2505,0.464868134,1.109767251,0.846942231,1.46037027,0.631757386,DB0065410012735_,0.459249842,0.10415031,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,latanoprost,DB00654
,69006,DB00654,10025482,83,3733,31,2567,0.003703383,1.840960139,1.201112776,2.887378441,0.016031525,DB0065410025482_,4.133198178,0.61028725,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,69007,DB00761,10025482,539,14768,180,8445,1.79355943931813e-10,1.712319679,1.440601025,2.042879368,5.62909968507188e-09,DB0076110025482_,18.99531632,0.537848989,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,69008,DB00471,10033371,570,13619,117,5348,2.53212013768953e-11,1.913034459,1.561227618,2.360522599,9.0615082122763e-10,DB0047110033371_,20.82181535,0.648690704,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,69009,DB00741,10033371,164,3930,84,3090,0.001716601,1.534987443,1.167685127,2.030137308,0.008573276,DB0074110033371_,4.759105344,0.4285222,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,69010,DB08932,10033371,1111,18332,245,6352,8.20952699128408e-11,1.571287278,1.362838467,1.8171226,2.70579833186084e-09,DB0893210033371_,19.72786884,0.451895206,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,69012,DB00169,10043458,40,38651,13,18162,0.30244234,1.445842121,0.757318056,2.947017457,0.468827608,DB0016910043458_,0.757520151,0.368691934,NA,10043458,Thirst,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,69027,DB00115,10065154,106,18319,45,10427,0.106898544,1.340746629,0.93672116,1.946580843,0.221473022,DB0011510065154_,1.507454493,0.293226645,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,cyanocobalamin,DB00115
,69028,DB00169,10065154,207,38484,85,18090,0.314391081,1.144737529,0.884581314,1.492474739,0.481992975,DB0016910065154_,0.72982574,0.135175378,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,cholecalciferol,DB00169
,69029,DB00175,10065154,52,8079,33,6073,0.509925012,1.184478656,0.75028863,1.894190319,0.670487429,DB0017510065154_,0.399750326,0.169302725,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,pravastatin,DB00175
,69030,DB00404,10065154,95,19797,33,9829,0.089840583,1.429271427,0.951911653,2.194938134,0.194960555,DB0040410065154_,1.634958025,0.357164823,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,alprazolam,DB00404
,69031,DB00471,10065154,81,14108,23,5442,0.227278937,1.358416178,0.8451067,2.264988774,0.382533575,DB0047110065154_,0.960938851,0.306319446,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,montelukast,DB00471
,69033,DB00682,10065154,72,19387,88,16276,0.02081943,0.68690371,0.495590597,0.949411152,0.063781142,DB0068210065154_,2.75229772,-0.375561157,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,69034,DB00736,10065154,48,10543,18,5535,0.244450402,1.399953413,0.798642692,2.559835681,0.40308515,DB0073610065154_,0.90860745,0.33643896,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,esomeprazole,DB00736
,69036,DB00761,10065154,80,15227,36,8589,0.286860402,1.253499222,0.835023429,1.914588499,0.451626227,DB0076110065154_,0.794900373,0.225939018,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,potassium chloride,DB00761
,69037,DB00904,10065154,118,22951,66,14390,0.494659456,1.120997826,0.821861195,1.540190934,0.657155228,DB0090410065154_,0.419835021,0.114219205,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,ondansetron,DB00904
,69038,DB00996,10065154,228,38725,104,22321,0.051887755,1.263661842,0.997184201,1.610224425,0.128588095,DB0099610065154_,2.051141043,0.23401373,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,gabapentin,DB00996
,69040,DB08932,10065154,47,19396,24,6573,0.102409012,0.66366015,0.397351424,1.135685411,0.21460742,DB0893210065154_,1.538944871,-0.409985083,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,69042,DB00682,10019641,26,19433,38,16326,0.032313418,0.574833412,0.334944855,0.972220823,0.08978394,DB0068210019641_,2.41034916,-0.553674998,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,warfarin,DB00682
,69045,DB00313,10001488,17,1222,34,1483,0.117348095,0.60689932,0.316323213,1.123248725,0.237204958,DB0031310001488_,1.438830709,-0.499392366,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,valproic acid,DB00313
,69058,DB00051,10021688,42,25689,8,11412,0.021630662,2.332199159,1.08120682,5.753302959,0.065790551,DB0005110021688_,2.721279047,0.846811668,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,adalimumab,DB00051
,69060,DB00051,10050584,184,25547,57,11363,0.017100828,1.435827055,1.060436892,1.969835101,0.054641692,DB0005110050584_,2.906958101,0.361741028,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,69065,DB09072,10016330,60,6411,22,2513,0.90189842,1.069034926,0.64460903,1.834317912,0.957157564,DB0907210016330_,0.043787257,0.066756303,NA,10016330,Feeling drunk,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,69069,DB09072,10057667,48,6423,22,2513,0.593503632,0.853670104,0.504224387,1.48828245,0.739517149,DB0907210057667_,0.301757807,-0.158210455,NA,10057667,Bipolar disorder,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,69076,DB00264,10072268,36,29571,57,24835,0.003313185,0.530439971,0.339323576,0.81946202,0.014659889,DB0026410072268_,4.222640124,-0.634048484,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,metoprolol,DB00264
,69078,DB00512,10072268,26,4711,32,5066,0.693007641,0.87373878,0.49933032,1.515775728,0.815002163,DB0051210072268_,0.204564511,-0.134973826,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,vancomycin,DB00512
,69079,DB00635,10072268,71,32982,51,23743,1,1.002182391,0.689280672,1.466181481,1,DB0063510072268_,0,0.002180013,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,prednisone,DB00635
,69084,DB00999,10069327,127,21303,64,12175,0.450861991,1.134117617,0.832606902,1.557829667,0.618518269,DB0099910069327_,0.48042855,0.125854918,NA,10069327,Product quality issue,10077536,Product issues,Prod,hydrochlorothiazide,DB00999
,69089,DB01202,10016288,26,6688,49,5669,0.001006011,0.449792424,0.267968486,0.739119472,0.005532007,DB0120210016288_,5.197204614,-0.798969082,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,levetiracetam,DB01202
,69091,DB14500,10016288,36,7773,22,4051,0.580115402,0.852832444,0.487554261,1.523955472,0.72869727,DB1450010016288_,0.316496901,-0.159192182,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,potassium,DB14500
,69092,DB00073,10073755,42,7364,66,6341,0.002528664,0.547990745,0.362481728,0.820326885,0.011762841,DB0007310073755_,4.442809811,-0.60149688,NA,10073755,Pneumocystis jirovecii pneumonia,10021881,Infections and infestations,Infec,rituximab,DB00073
,69098,DB00563,10073755,33,46613,56,15292,2.93146440375509e-14,0.193328323,0.121748876,0.302594332,1.61628071556784e-12,DB0056310073755_,27.15089346,-1.643365381,male,10073755,Pneumocystis jirovecii pneumonia,10021881,Infections and infestations,Infec,methotrexate,DB00563
,69103,DB01015,10073755,29,9858,62,9319,0.000205297,0.442183548,0.273976713,0.698532099,0.00147277,DB0101510073755_,6.520610166,-0.816030215,NA,10073755,Pneumocystis jirovecii pneumonia,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,69121,DB00252,10016173,69,2163,46,1862,0.217320194,1.291181447,0.871487765,1.92832994,0.370264872,DB0025210016173_,0.99353666,0.25555765,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,phenytoin,DB00252
,69122,DB00555,10016173,227,6820,96,3390,0.207250164,1.175321881,0.918344099,1.513637272,0.357933609,DB0055510016173_,1.027407758,0.161542051,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,lamotrigine,DB00555
,69123,DB01224,10016173,285,7823,210,5707,0.926205393,0.99005591,0.822717863,1.192907713,0.968639813,DB0122410016173_,0.031862446,-0.009993863,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,69125,DB00555,10024264,46,7001,45,3441,0.001563418,0.50244324,0.325093931,0.7770142,0.007953249,DB0055510024264_,4.834174793,-0.688272602,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,69126,DB01076,10024264,108,25639,116,25467,0.592332966,0.924813999,0.704495668,1.213151285,0.738519685,DB0107610024264_,0.303107522,-0.078162644,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,69127,DB00252,10070863,170,2062,173,1735,0.10088053,0.826866179,0.658621187,1.03795951,0.212126425,DB0025210070863_,1.550572836,-0.190112412,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,phenytoin,DB00252
,69133,DB00341,10003988,223,11182,68,5000,0.005765169,1.466359513,1.110536837,1.957458024,0.022935898,DB0034110003988_,3.775051984,0.382782808,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,69137,DB00169,10005728,62,38629,24,18151,0.487804375,1.213832735,0.746462374,2.034445073,0.65152124,DB0016910005728_,0.428445281,0.193782903,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,cholecalciferol,DB00169
,69139,DB00451,10005728,72,47199,31,15388,0.207552574,0.757220437,0.490366511,1.194423586,0.358326398,DB0045110005728_,1.026310982,-0.27810087,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,levothyroxine,DB00451
,69144,DB00341,10013496,33,11372,17,5051,0.64596638,0.86221434,0.46613475,1.652106338,0.781606385,DB0034110013496_,0.246404009,-0.148251385,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,69145,DB00451,10013496,163,47108,34,15385,0.016077828,1.565655719,1.076115332,2.338795919,0.052019414,DB0045110013496_,2.956138292,0.448304726,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,69146,DB00588,10013496,41,16483,19,8449,0.785761772,1.10610386,0.627152081,2.019104916,0.883734037,DB0058810013496_,0.123599125,0.100843804,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,69158,DB00341,10016322,170,11235,49,5019,0.006303809,1.549838313,1.119741515,2.179520666,0.024638717,DB0034110016322_,3.703436197,0.438150611,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,69159,DB00588,10016322,286,16238,64,8404,8.58230227805073e-11,2.312739938,1.755828637,3.086471305,2.81806140385463e-09,DB0058810016322_,19.68721663,0.838432942,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,69162,DB00126,10020642,69,10102,38,5907,0.840838114,1.061758649,0.703579317,1.624016708,0.918695734,DB0012610020642_,0.084800295,0.059926636,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,ascorbic acid,DB00126
,69163,DB00341,10020642,92,11313,46,5022,0.517383873,0.887841352,0.615620265,1.296053616,0.677009837,DB0034110020642_,0.390069475,-0.11896221,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,cetirizine,DB00341
,69164,DB00588,10020642,131,16393,44,8424,0.015929716,1.529930244,1.078494729,2.207016496,0.051664209,DB0058810020642_,2.962990025,0.425222142,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,69167,DB00341,10020937,173,11232,27,5041,1.78696632937954e-08,2.875542998,1.906261322,4.495412545,3.78640950969295e-07,DB0034110020937_,14.78667744,1.056241525,female,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,69170,DB00126,10021789,112,10059,56,5889,0.376730616,1.17091346,0.840735204,1.646697776,0.546578586,DB0012610021789_,0.604077182,0.157784179,NA,10021789,Infection,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,69171,DB00341,10021789,124,11281,47,5021,0.404861263,1.174244268,0.831530608,1.682621459,0.574594547,DB0034110021789_,0.554090623,0.160624765,NA,10021789,Infection,10021881,Infections and infestations,Infec,cetirizine,DB00341
,69172,DB00588,10021789,199,16325,103,8365,0.951250244,0.989982295,0.775316271,1.270340978,0.989419202,DB0058810021789_,0.010637172,-0.01006822,NA,10021789,Infection,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,69175,DB00588,10027175,188,16336,62,8406,0.001979765,1.560280228,1.163591555,2.116821655,0.009646514,DB0058810027175_,4.641158668,0.444865438,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,69186,DB00169,10029446,42,38649,30,18145,0.099212616,0.65727111,0.401608189,1.087956294,0.209647367,DB0016910029446_,1.562328364,-0.419658697,NA,10029446,Nocturia,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,69188,DB00451,10029446,41,47230,25,15394,0.015050585,0.534563695,0.317283608,0.917538443,0.049453668,DB0045110029446_,3.006719046,-0.626304387,NA,10029446,Nocturia,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,69192,DB00169,10029883,49,38642,28,18147,0.395000035,0.821853399,0.506225172,1.358557669,0.564853703,DB0016910029883_,0.571188514,-0.196193247,NA,10029883,Obesity,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,69198,DB00588,10036018,58,16466,26,8442,0.644628338,1.143683522,0.707980787,1.89414642,0.780618245,DB0058810036018_,0.247669051,0.134254213,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,fluticasone propionate,DB00588
,69214,DB00451,10043730,84,47187,16,15403,0.047903493,1.713650101,0.995879837,3.135806319,0.121193831,DB0045110043730_,2.110364109,0.538625658,NA,10043730,Thyroid function test abnormal,10022891,Investigations,Inv,levothyroxine,DB00451
,69218,DB00126,10046735,82,10089,37,5908,0.215103483,1.297769919,0.868825966,1.971325942,0.367536324,DB0012610046735_,1.000933123,0.260647344,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,ascorbic acid,DB00126
,69221,DB00126,10047340,54,10117,14,5931,0.00522986,2.261111452,1.237336484,4.411879881,0.021210749,DB0012610047340_,3.853247177,0.815856485,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,ascorbic acid,DB00126
,69222,DB00169,10047340,153,38538,38,18137,0.000241498,1.89487137,1.320242883,2.780697081,0.001685324,DB0016910047340_,6.38579739,0.639150958,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,cholecalciferol,DB00169
,69223,DB00588,10047340,90,16434,21,8447,0.000589447,2.202776323,1.357024833,3.733146119,0.003543015,DB0058810047340_,5.642777275,0.78971853,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,fluticasone propionate,DB00588
,69278,DB00203,10020937,96,13782,66,8872,0.686946735,0.936349699,0.676541083,1.302720227,0.811195244,DB0020310020937_,0.209246509,-0.065766262,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,69279,DB00338,10020937,436,33238,175,22097,8.48774106263236e-09,1.656313158,1.38551395,1.98705965,1.94084622732746e-07,DB0033810020937_,15.45497157,0.504594143,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,69280,DB00390,10020937,39,4106,15,3286,0.018588669,2.080538803,1.119069526,4.070206933,0.058323266,DB0039010020937_,2.841754189,0.7326269,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,digoxin,DB00390
,69282,DB00203,10033775,76,13802,38,8900,0.212241733,1.289645631,0.861813239,1.959079876,0.364067543,DB0020310033775_,1.010415871,0.254367476,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,69320,DB00563,10004146,51,46595,23,15325,0.2246955,0.729299653,0.437506007,1.250810747,0.379410067,DB0056310004146_,0.969137688,-0.315670585,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,methotrexate,DB00563
,69322,DB00635,10019022,49,33004,31,23763,0.650434482,1.138031314,0.71107674,1.84691838,0.785013507,DB0063510019022_,0.242054356,0.129299852,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,69327,DB00563,10041823,35,46611,21,15327,0.04235691,0.548066015,0.310139502,0.991125159,0.110398856,DB0056310041823_,2.20365551,-0.601359534,NA,10041823,Squamous cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,methotrexate,DB00563
,69338,DB00455,10000059,146,9255,50,5068,0.004117623,1.598931684,1.150039389,2.255332826,0.017487754,DB0045510000059_,4.046254386,0.469335709,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,69339,DB01224,10000059,53,8055,21,5896,0.017793319,1.847262011,1.094139454,3.228189183,0.056378351,DB0122410000059_,2.87567005,0.613704549,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,quetiapine,DB01224
,69343,DB00370,10020642,49,4492,19,3644,0.006614331,2.091883416,1.206831195,3.770154643,0.025603078,DB0037010020642_,3.665042711,0.738064816,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,mirtazapine,DB00370
,69350,DB00813,10033557,40,10532,16,10152,0.002884884,2.409529684,1.318679204,4.612004201,0.013092054,DB0081310033557_,4.335749774,0.879431577,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,fentanyl,DB00813
,69353,DB00829,10047571,60,7992,23,4431,0.136628726,1.44629724,0.879553712,2.454914578,0.265010225,DB0082910047571_,1.327986871,0.369006663,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,diazepam,DB00829
,69354,DB00370,10053762,128,4413,115,3548,0.395394009,0.894886948,0.687422263,1.166111868,0.565048199,DB0037010053762_,0.570844244,-0.111057884,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,mirtazapine,DB00370
,69355,DB00829,10053762,219,7833,129,4325,0.570534968,0.937378529,0.748205802,1.178209991,0.721038134,DB0082910053762_,0.327063253,-0.064668099,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,69362,DB00758,10018852,47,8253,68,10006,0.397790207,0.837996062,0.564478254,1.234884239,0.567463029,DB0075810018852_,0.56657968,-0.176741878,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,clopidogrel,DB00758
,69375,DB00005,10051055,33,128049,29,42390,0.000182976,0.376708979,0.221740772,0.643229091,0.001338026,DB0000510051055_,6.616559838,-0.976282329,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,etanercept,DB00005
,69379,DB00073,10020983,66,7340,34,6373,0.015325889,1.685371446,1.096469653,2.633170692,0.050160753,DB0007310020983_,2.992522379,0.521985982,NA,10020983,Hypogammaglobulinaemia,10021428,Immune system disorders,Immun,rituximab,DB00073
,69388,DB00099,10006002,74,2311,44,1911,0.091625668,1.390614164,0.939821135,2.078733342,0.197854918,DB0009910006002_,1.620221255,0.329745494,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,filgrastim,DB00099
,69389,DB00099,10008531,32,2353,35,1920,0.265638327,0.746095284,0.445362408,1.2459084,0.427719283,DB0009910008531_,0.84928818,-0.29290196,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,filgrastim,DB00099
,69391,DB00099,10025482,54,2331,32,1923,0.155101968,1.392026873,0.87876247,2.237582393,0.290933792,DB0009910025482_,1.234659556,0.330760867,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,filgrastim,DB00099
,69393,DB00099,10054112,44,2341,32,1923,0.642920206,1.12943465,0.697120307,1.84812449,0.779283743,DB0009910054112_,0.249380059,0.121717198,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,filgrastim,DB00099
,69398,DB00682,10022067,58,19401,16,16348,2.00956429521436e-05,3.054346275,1.731509362,5.695916821,0.000200499,DB0068210022067_,8.514702511,1.116565584,female,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,69401,DB00843,10012735,82,2112,100,2073,0.17275708,0.804899844,0.58973786,1.09604145,0.314473564,DB0084310012735_,1.156855265,-0.217037427,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,donepezil,DB00843
,69402,DB01043,10012735,51,1350,53,1357,0.920507891,0.96725704,0.640350403,1.459884121,0.964812755,DB0104310012735_,0.035821232,-0.033291007,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,memantine,DB01043
,69403,DB01043,10028813,61,1340,41,1369,0.043667036,1.51976935,0.998638691,2.333543028,0.112921249,DB0104310028813_,2.181064615,0.41855858,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,memantine,DB01043
,69407,DB00451,10040831,114,47157,30,15389,0.332899668,1.240063715,0.822888838,1.922040181,0.501893818,DB0045110040831_,0.6893667,0.215162761,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,69417,DB00367,10046735,85,22715,6,461,0.010062439,0.287541955,0.125860306,0.809636558,0.035740029,DB0036710046735_,3.331483945,-1.246386499,male,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,levonorgestrel,DB00367
,69418,DB00627,10046735,41,1288,12,1587,2.22020821977979e-06,4.207917218,2.158624386,8.831177145,2.90773159227263e-05,DB0062710046735_,10.44555221,1.436967803,female,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,niacin,DB00627
,69420,DB06292,10013709,34,1323,26,1207,0.516497588,1.192952559,0.690428087,2.083397314,0.676136217,DB0629210013709_,0.391360718,0.176431376,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dapagliflozin,DB06292
,69446,DB00476,10061284,63,17194,30,6147,0.195840723,0.750777597,0.478288143,1.202714471,0.344095816,DB0047610061284_,1.066835127,-0.286645814,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,69447,DB00996,10061284,93,38860,42,22383,0.210536178,1.275423841,0.87655759,1.883299793,0.361831414,DB0099610061284_,1.016576884,0.243278547,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,69449,DB00531,10009657,42,7210,52,6464,0.121419485,0.724144094,0.46974889,1.110459945,0.243477174,DB0053110009657_,1.412732081,-0.322764881,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,69450,DB00904,10009657,86,22983,42,14414,0.20299975,1.284156575,0.877513146,1.905344408,0.352573572,DB0090410009657_,1.042495963,0.250102141,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,69463,DB00682,10039203,39,19420,40,16324,0.428923023,0.819569628,0.513255667,1.307701459,0.597421597,DB0068210039203_,0.515132222,-0.198975921,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,69464,DB00820,10039203,36,11879,17,5799,1,1.033748983,0.56528976,1.96441328,1,DB0082010039203_,0,0.033191983,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,tadalafil,DB00820
,69467,DB00294,10028813,357,14014,6,162,0.31813024,0.687845448,0.306222184,1.914819818,0.486109369,DB0029410028813_,0.721321641,-0.374191105,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,etonogestrel,DB00294
,69469,DB00264,10001053,145,29462,137,24755,0.337894113,0.889302479,0.698766328,1.132287436,0.506976351,DB0026410001053_,0.679290922,-0.117317855,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,69471,DB00761,10001053,163,15144,81,8544,0.383763451,1.135347137,0.863323071,1.502922546,0.553752476,DB0076110001053_,0.591037487,0.126938451,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,69473,DB00370,10035664,159,4382,148,3515,0.219139528,0.86178165,0.681430884,1.090379847,0.372447221,DB0037010035664_,0.987659939,-0.148753347,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,mirtazapine,DB00370
,69474,DB06723,10035664,33,997,35,575,0.014831909,0.543968578,0.323794635,0.912128284,0.048875662,DB0672310035664_,3.018475722,-0.608863794,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,aluminum hydroxide,DB06723
,69475,DB09104,10035664,48,1002,55,817,0.10356133,0.711729796,0.467504627,1.080415837,0.216383908,DB0910410035664_,1.530701097,-0.34005694,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,magnesium hydroxide,DB09104
,69480,DB06228,10013710,140,15772,158,15918,0.351990621,0.894281776,0.706394939,1.131163991,0.521756877,DB0622810013710_,0.650553553,-0.111734367,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,69481,DB00216,10033371,49,874,11,97,0.04967335,0.494808669,0.243483518,1.091279526,0.124408195,DB0021610033371_,2.084187226,-0.703584119,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,eletriptan,DB00216
,69482,DB04861,10011224,47,1918,20,1367,0.059919831,1.674647946,0.968032337,2.998064255,0.143317963,DB0486110011224_,1.942689602,0.515602962,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nebivolol,DB04861
,69483,DB04861,10019211,128,1837,44,1343,1.08736683763993e-05,2.126319988,1.486834773,3.090004254,0.000116625,DB0486110019211_,9.056549757,0.75439278,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,nebivolol,DB04861
,69487,DB00788,10000081,143,9213,68,4993,0.424196601,1.139701271,0.846203423,1.547692813,0.593006657,DB0078810000081_,0.522549654,0.130766185,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,69488,DB01175,10000081,177,10547,46,4846,0.000453154,1.767892116,1.269265335,2.506320564,0.002845815,DB0117510000081_,5.861905891,0.569787942,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,69493,DB00788,10012735,407,8949,179,4882,0.019130511,1.240347701,1.034165503,1.492415327,0.059677842,DB0078810012735_,2.818794489,0.215391744,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,69499,DB00091,10015946,324,5186,76,2594,6.72234302718933e-10,2.13222757,1.648275771,2.787339053,1.92795184364071e-08,DB0009110015946_,17.76422253,0.757167241,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,cyclosporine,DB00091
,69500,DB00091,10051116,64,5446,7,2663,1.00960911028668e-05,4.470683561,2.045203671,11.57950105,0.000109501,DB0009110051116_,9.119576571,1.497541319,female,10051116,Foreign body sensation in eyes,10015919,Eye disorders,Eye,cyclosporine,DB00091
,69502,DB06228,10018838,52,15860,33,16043,0.038800663,1.593906621,1.010436075,2.546924444,0.103257612,DB0622810018838_,2.27052833,0.466187997,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,rivaroxaban,DB06228
,69503,DB01261,10003658,28,3753,53,3250,0.000710989,0.45754216,0.277963298,0.738523625,0.004146977,DB0126110003658_,5.485375685,-0.781886246,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,sitagliptin,DB01261
,69511,DB01261,10008479,64,3717,48,3255,0.445940001,1.167582249,0.788030334,1.740021026,0.61378923,DB0126110008479_,0.488103683,0.154935157,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,69518,DB01261,10017885,51,3730,68,3235,0.025752178,0.650515537,0.441958444,0.952306168,0.075152215,DB0126110017885_,2.588239692,-0.429990097,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,sitagliptin,DB01261
,69519,DB00331,10019063,80,24866,89,20663,0.063128513,0.746953205,0.544955629,1.022408995,0.14918358,DB0033110019063_,1.902577648,-0.29175274,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,metformin,DB00331
,69522,DB00331,10020100,66,24880,33,20719,0.015405501,1.665492205,1.080308846,2.613095968,0.05034922,DB0033110020100_,2.988772151,0.510120699,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,69529,DB01261,10027459,24,3757,31,3272,0.174584916,0.674294897,0.377838906,1.189671882,0.316902492,DB0126110027459_,1.14916115,-0.394087731,NA,10027459,Metastases to lymph nodes,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sitagliptin,DB01261
,69531,DB00331,10029148,96,24850,82,20670,0.880268555,0.973796528,0.717202526,1.324781159,0.949771523,DB0033110029148_,0.051533826,-0.0265529,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,69532,DB01261,10029148,23,3758,42,3261,0.003883633,0.475241251,0.272195036,0.810510136,0.01665138,DB0126110029148_,4.095262161,-0.743932707,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,sitagliptin,DB01261
,69534,DB01261,10031161,29,3752,33,3270,0.308719949,0.765927515,0.447575887,1.304206067,0.476034641,DB0126110031161_,0.742264653,-0.266667742,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,sitagliptin,DB01261
,69541,DB01261,10037660,60,3721,47,3256,0.62575394,1.117028994,0.747509628,1.677951591,0.765305338,DB0126110037660_,0.26748039,0.110672477,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,69543,DB01261,10040047,38,3743,55,3248,0.016026007,0.599588631,0.384678367,0.92588199,0.051883679,DB0126110040047_,2.958751001,-0.511511474,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,sitagliptin,DB01261
,69582,DB00331,10063829,41,24905,34,20718,1,1.003150775,0.620874168,1.630376215,1,DB0033110063829_,0,0.003145822,NA,10063829,Device malfunction,10077536,Product issues,Prod,metformin,DB00331
,69584,DB01276,10063829,39,1978,22,1489,0.299232142,1.334366976,0.768071243,2.373639941,0.465251889,DB0127610063829_,0.765176323,0.288457004,NA,10063829,Device malfunction,10077536,Product issues,Prod,exenatide,DB01276
,69585,DB01224,10057667,50,8058,22,5895,0.054905117,1.662599617,0.987181077,2.886545268,0.134156885,DB0122410057667_,2.008745382,0.508382412,NA,10057667,Bipolar disorder,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,69590,DB01268,10048245,35,2108,52,3078,1,0.982796883,0.619007728,1.543728318,1,DB0126810048245_,0,-0.01735281,NA,10048245,Yellow skin,10040785,Skin and subcutaneous tissue disorders,Skin,sunitinib,DB01268
,69592,DB00126,10050584,120,10051,39,5906,0.001202419,1.807947483,1.248272299,2.669765057,0.006413468,DB0012610050584_,5.049355085,0.592192215,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,ascorbic acid,DB00126
,69593,DB01268,10050584,23,2120,35,3095,1,0.959369853,0.539550484,1.675614863,1,DB0126810050584_,0,-0.041478613,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,sunitinib,DB01268
,69599,DB00374,10039203,45,17671,14,5710,1,1.038645956,0.559376266,2.050463345,1,DB0037410039203_,0,0.037917899,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,69600,DB06403,10039203,40,21431,13,6648,0.871965603,0.954474194,0.499709705,1.946211878,0.943737786,DB0640310039203_,0.057906921,-0.046594673,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,ambrisentan,DB06403
,69612,DB00682,10031009,34,19425,19,16345,0.16855108,1.505716962,0.834480109,2.795485025,0.308967723,DB0068210031009_,1.174518462,0.409269172,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,69615,DB00820,10035598,150,11765,56,5760,0.086361773,1.31141785,0.957011075,1.819078674,0.188995022,DB0082010035598_,1.666034604,0.27110888,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,69616,DB06403,10035598,125,21346,38,6623,1,1.02062633,0.703988434,1.510415316,1,DB0640310035598_,0,0.020416488,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,69622,DB00682,10044034,50,19409,23,16341,0.018093886,1.830246006,1.095731349,3.144343166,0.057077442,DB0068210044034_,2.863346302,0.604450387,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,69625,DB00682,10046274,54,19405,90,16274,5.19373179674233e-05,0.503205447,0.352027533,0.713400809,0.000456198,DB0068210046274_,7.692583714,-0.686756748,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,69643,DB00108,10029148,63,10131,25,3270,0.38441533,0.813385385,0.503464653,1.351873512,0.554482888,DB0010810029148_,0.589719334,-0.206550254,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,natalizumab,DB00108
,69644,DB00115,10029148,74,18351,45,10427,0.703675946,0.934372916,0.635993446,1.386290329,0.822250872,DB0011510029148_,0.195709734,-0.067879653,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,cyanocobalamin,DB00115
,69652,DB00682,10005619,48,19411,16,16348,0.000944277,2.526468525,1.409041724,4.768489421,0.005253536,DB0068210005619_,5.248853974,0.926822488,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,warfarin,DB00682
,69653,DB00820,10005619,48,11867,11,5805,0.018421788,2.134488461,1.092059545,4.561245375,0.057910268,DB0082010005619_,2.848860562,0.758227021,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,tadalafil,DB00820
,69654,DB00820,10018836,59,11856,25,5791,0.641469596,1.152710519,0.709975381,1.922990757,0.778171378,DB0082010018836_,0.250808498,0.142116142,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,69655,DB00820,10055798,96,11819,41,5775,0.522881426,1.144068773,0.784700398,1.694391968,0.681286752,DB0082010055798_,0.383771986,0.134591007,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,tadalafil,DB00820
,69659,DB00564,10070863,206,2398,129,1334,0.31300785,0.888379743,0.70197169,1.127459431,0.48053099,DB0056410070863_,0.732863558,-0.118355989,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,carbamazepine,DB00564
,69661,DB08895,10047571,129,27985,16,6630,0.010923801,1.910053902,1.131520269,3.443975062,0.038207864,DB0889510047571_,3.26471391,0.647131462,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,tofacitinib,DB08895
,69667,DB08899,10016173,8,241,297,7836,0.863803494,0.875822657,0.370330328,1.776679938,0.937257991,DB0889910016173_,0.064796697,-0.132591655,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,enzalutamide,DB08899
,69672,DB00257,10012735,66,886,40,582,0.757960707,1.083822774,0.710111207,1.671723575,0.864803517,DB0025710012735_,0.145252945,0.080494397,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,clotrimazole,DB00257
,69673,DB00878,10012735,73,1113,39,881,0.062460243,1.481355664,0.980082536,2.268478911,0.148040352,DB0087810012735_,1.910270397,0.392957658,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,chlorhexidine,DB00878
,69675,DB11093,10012735,111,1546,28,632,0.025573748,1.620282183,1.049986166,2.575113415,0.074768475,DB1109310012735_,2.593358937,0.482600321,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,calcium citrate,DB11093
,69676,DB00878,10013573,33,1153,19,901,0.323766846,1.357043513,0.743658009,2.544068546,0.492218488,DB0087810013573_,0.70883258,0.305308446,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,chlorhexidine,DB00878
,69678,DB01132,10013573,38,1247,40,1490,0.645048317,1.135071557,0.703773509,1.827949734,0.780833021,DB0113210013573_,0.247393954,0.126695695,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pioglitazone,DB01132
,69679,DB00257,10016256,78,874,45,577,0.503208141,1.14418838,0.770229623,1.716656731,0.664364157,DB0025710016256_,0.408924851,0.134695547,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,clotrimazole,DB00257
,69681,DB01062,10016256,298,4188,120,1625,0.735347253,0.963570822,0.77069293,1.210606824,0.847114105,DB0106210016256_,0.165919877,-0.037109289,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,69682,DB00257,10019211,66,886,22,600,0.004761114,2.030752122,1.221245435,3.495820115,0.019666202,DB0025710019211_,3.928853735,0.708406228,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,clotrimazole,DB00257
,69683,DB00333,10019211,83,2988,60,3092,0.04194915,1.431391309,1.010431248,2.038058918,0.109611153,DB0033310019211_,2.210816144,0.358646914,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,methadone,DB00333
,69685,DB01016,10019211,34,1067,27,1201,0.195001558,1.417180839,0.823884391,2.459729091,0.342988219,DB0101610019211_,1.07005918,0.348669574,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,glyburide,DB01016
,69686,DB01062,10019211,200,4286,45,1700,0.000469615,1.762704195,1.263300222,2.505660675,0.002930979,DB0106210019211_,5.832418678,0.566849104,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,69687,DB01132,10019211,52,1233,32,1498,0.002597664,1.973747407,1.238048052,3.189954937,0.01202044,DB0113210019211_,4.421146784,0.679933973,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pioglitazone,DB01132
,69688,DB01377,10019211,163,3633,53,2617,2.22099984710355e-07,2.215116795,1.608424918,3.09269334,3.72562929492982e-06,DB0137710019211_,12.50027478,0.795305131,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,magnesium oxide,DB01377
,69689,DB11093,10019211,90,1567,16,644,0.001306024,2.311051297,1.335699677,4.24979385,0.006856856,DB1109310019211_,4.982506281,0.837702528,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,calcium citrate,DB11093
,69690,DB00257,10028813,69,883,20,602,0.000725726,2.350928706,1.394416886,4.128984238,0.004217956,DB0025710028813_,5.468404577,0.854810444,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,clotrimazole,DB00257
,69691,DB00878,10028813,82,1104,26,894,2.2906858710097e-05,2.552800055,1.608584632,4.173657337,0.000224248,DB0087810028813_,8.402756479,0.937190818,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,chlorhexidine,DB00878
,69693,DB01016,10028813,57,1044,50,1178,0.234165549,1.286176171,0.855834607,1.938113921,0.391032301,DB0101610028813_,0.938965112,0.251673608,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,glyburide,DB01016
,69694,DB11093,10028813,99,1558,16,644,0.000271863,2.556766934,1.484565668,4.683649185,0.001861404,DB1109310028813_,6.286424234,0.938743544,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,calcium citrate,DB11093
,69695,DB00186,10047513,147,16754,49,9959,0.00034661,1.783238601,1.281180182,2.519675937,0.0022767,DB0018610047513_,6.085028063,0.57843115,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,lorazepam,DB00186
,69698,DB00341,10047513,96,11309,30,5038,0.099355652,1.42556091,0.936004129,2.228863382,0.209898996,DB0034110047513_,1.561128837,0.354565357,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,cetirizine,DB00341
,69699,DB00471,10047513,101,14088,20,5445,0.004306741,1.951775177,1.198187395,3.333649667,0.018138674,DB0047110047513_,4.009708918,0.668739306,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,montelukast,DB00471
,69700,DB00476,10047513,175,17082,51,6126,0.224551543,1.230549427,0.89482562,1.718170767,0.379205737,DB0047610047513_,0.969676379,0.207460758,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,duloxetine,DB00476
,69701,DB00761,10047513,110,15197,46,8579,0.094298022,1.349921219,0.947578281,1.950392303,0.202244493,DB0076110047513_,1.598277954,0.300046234,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,potassium chloride,DB00761
,69708,DB11089,10047513,78,10097,49,8358,0.152121198,1.317654674,0.909020025,1.926261856,0.286888301,DB1108910047513_,1.248662335,0.275853394,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,docusate,DB11089
,69709,DB00257,10047700,35,917,18,604,0.475445809,1.280550028,0.698412513,2.425152942,0.641090266,DB0025710047700_,0.444585012,0.247289695,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,clotrimazole,DB00257
,69710,DB00471,10047700,406,13783,113,5352,0.001733134,1.395070808,1.127054972,1.738379653,0.008640193,DB0047110047700_,4.751330403,0.332945173,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,69711,DB00878,10047700,52,1134,23,897,0.023845071,1.78788799,1.06551858,3.085995333,0.070873263,DB0087810047700_,2.646862025,0.58103503,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,chlorhexidine,DB00878
,69713,DB01016,10047700,32,1069,34,1194,0.900687325,1.051231811,0.623256335,1.769265138,0.956760749,DB0101610047700_,0.04420192,0.04996263,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,glyburide,DB01016
,69714,DB11093,10047700,44,1613,7,653,0.017927507,2.543856981,1.128935319,6.728080019,0.056698895,DB1109310047700_,2.870000556,0.933681426,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,calcium citrate,DB11093
,69722,DB00126,10013774,47,10124,9,5936,0.000788445,3.061759768,1.482005625,7.111418823,0.004519522,DB0012610013774_,5.399348945,1.118989838,female,10013774,Dry eye,10015919,Eye disorders,Eye,ascorbic acid,DB00126
,69729,DB01590,10013781,42,4696,25,2842,1,1.016727445,0.603955886,1.744875782,1,DB0159010013781_,0,0.016589083,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,everolimus,DB01590
,69738,DB00126,10023232,122,10049,29,5916,2.54888761710046e-06,2.476539366,1.638497307,3.857582162,3.27599890254367e-05,DB0012610023232_,10.32630263,0.906862169,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,69740,DB01590,10023232,47,4691,32,2835,0.64113397,0.887654125,0.553096741,1.441216614,0.777943746,DB0159010023232_,0.251101063,-0.119173111,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,everolimus,DB01590
,69741,DB09270,10023232,34,3080,20,2348,0.408621125,1.295912975,0.722749281,2.382526454,0.578042423,DB0927010023232_,0.548108016,0.259215447,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,ubidecarenone,DB09270
,69752,DB01590,10030095,45,4693,20,2847,0.303764848,1.364904793,0.787734238,2.445347526,0.470324214,DB0159010030095_,0.754333005,0.311084677,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,69756,DB01590,10030124,80,4658,37,2830,0.179603118,1.313590991,0.876415212,2.001408001,0.323369268,DB0159010030124_,1.128960364,0.272764601,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,69757,DB09270,10030124,46,3068,34,2334,1,1.029256085,0.64416153,1.659334509,1,DB0927010030124_,0,0.028836294,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,69758,DB11133,10030124,30,2401,21,1553,0.774960264,0.924038925,0.50963322,1.704654964,0.877323349,DB1113310030124_,0.130879655,-0.079001081,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,69760,DB00451,10050296,90,47181,16,15403,0.023462985,1.836271144,1.07116558,3.350549231,0.069951177,DB0045110050296_,2.659957745,0.607736963,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,69771,DB00177,10069327,44,4756,17,2833,0.144209749,1.541648184,0.861275768,2.883848515,0.275857161,DB0017710069327_,1.28787208,0.432852094,NA,10069327,Product quality issue,10077536,Product issues,Prod,valsartan,DB00177
,69773,DB00060,10002948,45,9463,8,2457,0.395861347,1.46043776,0.680182959,3.592002939,0.565485476,DB0006010002948_,0.570070666,0.378736226,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,69778,DB00559,10011781,53,9606,6,3300,0.006326487,3.034517859,1.30375017,8.646427347,0.02470902,DB0055910011781_,3.700586903,1.110052552,female,10011781,Cystitis,10021881,Infections and infestations,Infec,bosentan,DB00559
,69781,DB08932,10058467,63,19380,26,6571,0.394155591,0.821555948,0.51219356,1.353206861,0.564091129,DB0893210058467_,0.572539465,-0.196555239,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,macitentan,DB08932
,69783,DB00559,10048908,46,9613,9,3297,0.161388116,1.75281586,0.846556886,4.077826564,0.29931816,DB0055910048908_,1.206248191,0.561223558,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,bosentan,DB00559
,69786,DB00316,10012373,266,65208,125,36828,0.091573518,1.20181033,0.967732482,1.499187309,0.197782246,DB0031610012373_,1.620588623,0.183829028,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,69788,DB01234,10012373,25,31600,35,32853,0.301490913,0.742614097,0.425945828,1.277018337,0.467781633,DB0123410012373_,0.759753688,-0.297578754,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,69792,DB08895,10048762,73,28041,13,6633,0.410616233,1.328285719,0.729950927,2.614437254,0.580010793,DB0889510048762_,0.544708567,0.283889177,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,69795,DB00973,10037844,108,3743,57,2964,0.013819487,1.500312039,1.074448281,2.113920655,0.0460708,DB0097310037844_,3.077575938,0.405673113,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ezetimibe,DB00973
,69796,DB00734,10069327,69,3981,109,4793,0.080731255,0.762169255,0.553738431,1.043102425,0.179565986,DB0073410069327_,1.71721253,-0.271586629,NA,10069327,Product quality issue,10077536,Product issues,Prod,risperidone,DB00734
,69797,DB00451,10042128,291,46980,86,15333,0.436201788,1.104352365,0.864756974,1.42261994,0.604755735,DB0045110042128_,0.502930646,0.099259068,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,69799,DB06643,10037377,54,52367,11,7504,0.263126143,0.703462015,0.363464151,1.492721093,0.424923704,DB0664310037377_,0.855845647,-0.351741398,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,denosumab,DB06643
,69800,DB06643,10037660,246,52175,57,7458,0.00166437,0.616916897,0.460306692,0.838961934,0.008365613,DB0664310037660_,4.783625631,-0.483020952,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,69803,DB00341,10003285,58,11347,14,5054,0.040094965,1.845185289,1.015328502,3.58580896,0.105866559,DB0034110003285_,2.24557586,0.6125797,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,69806,DB00316,10005425,129,65345,46,36907,0.00722581,1.583894598,1.122809108,2.269425637,0.027454363,DB0031610005425_,3.595230185,0.45988675,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,acetaminophen,DB00316
,69808,DB06643,10005425,174,52247,7,7508,0.000107203,3.57197688,1.696346816,9.019377086,0.000847085,DB0664310005425_,7.073710043,1.27311919,female,10005425,Blood cholesterol increased,10022891,Investigations,Inv,denosumab,DB06643
,69812,DB00316,10006811,64,65410,27,36926,0.229993308,1.338144805,0.84098062,2.183373072,0.385977597,DB0031610006811_,0.95197595,0.291284181,NA,10006811,Bursitis,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,69833,DB08816,10016173,20,1131,33,1869,1,1.001526762,0.541761169,1.807796381,1,DB0881610016173_,0,0.001525598,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ticagrelor,DB08816
,69834,DB00316,10017626,90,65384,36,36917,0.094311297,1.411540933,0.948921268,2.139956038,0.202257777,DB0031610017626_,1.59821227,0.344681968,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,69851,DB00341,10028391,64,11341,13,5055,0.008805152,2.194264786,1.195278495,4.347089648,0.032147151,DB0034110028391_,3.43743144,0.785847041,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,69861,DB00316,10039227,77,65397,29,36924,0.068285983,1.499139067,0.966379655,2.384349613,0.158196463,DB0031610039227_,1.843917579,0.404890988,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,69871,DB14512,10048959,50,4794,17,2395,0.193315592,1.469288562,0.830928743,2.723642442,0.340821003,DB1451210048959_,1.076397857,0.384778312,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,69882,DB00811,10027175,30,2768,27,4129,0.058495218,1.657261129,0.949927429,2.904356954,0.140679984,DB0081110027175_,1.961267583,0.505166317,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ribavirin,DB00811
,69883,DB08934,10027175,41,4448,51,6153,0.671543565,1.11206687,0.717387779,1.714484689,0.800722294,DB0893410027175_,0.222241091,0.106220329,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,sofosbuvir,DB08934
,69891,DB00258,10035664,34,644,30,713,0.442553021,1.254556564,0.735778253,2.148722651,0.610598192,DB0025810035664_,0.49331616,0.226782174,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,calcium acetate,DB00258
,69892,DB00364,10035664,132,2618,79,1321,0.262241157,0.843147849,0.62793311,1.138039299,0.42398947,DB0036410035664_,0.858046659,-0.170612953,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sucralfate,DB00364
,69893,DB01175,10035664,316,10408,180,4712,0.01811007,0.794828473,0.657551841,0.962993552,0.057121641,DB0117510035664_,2.862572228,-0.229628945,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,escitalopram,DB01175
,69895,DB00169,10040070,77,38614,64,18111,0.001049187,0.564331135,0.399575988,0.799257187,0.00573631,DB0016910040070_,5.160939116,-0.572114081,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,69898,DB00404,10040070,47,19845,28,9834,0.461842067,0.831818909,0.509880512,1.380283978,0.628981197,DB0040410040070_,0.463653916,-0.18414052,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,alprazolam,DB00404
,69899,DB00682,10040070,82,19377,90,16274,0.091165149,0.765217708,0.55990208,1.044608583,0.197115833,DB0068210040070_,1.623963739,-0.2675949,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,warfarin,DB00682
,69903,DB00169,10041101,74,38617,37,18138,0.760395444,0.939381151,0.624615589,1.434692458,0.866851465,DB0016910041101_,0.142887637,-0.06253397,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,69907,DB00682,10041101,23,19436,30,16334,0.128857032,0.644321553,0.357271454,1.147701404,0.253962008,DB0068210041101_,1.370570599,-0.439557372,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,69908,DB01234,10041101,53,31572,50,32838,0.623688271,1.102499564,0.734624033,1.656736067,0.7636851,DB0123410041101_,0.269599747,0.097579932,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,69912,DB00563,10020993,30,46616,25,15323,0.0008406,0.394454758,0.224176118,0.699708499,0.004769435,DB0056310020993_,5.345527328,-0.930250826,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,69914,DB01234,10020993,20,31605,45,32843,0.003966486,0.461883708,0.258313925,0.798570289,0.01696511,DB0123410020993_,4.076596376,-0.772442133,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,69928,DB00281,10013700,374,11084,65,5606,1.84929879443004e-18,2.909994063,2.226293819,3.855862346,1.65617781300149e-16,DB0028110013700_,36.33684906,1.068151041,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,lidocaine,DB00281
,69932,DB00126,10011906,287,9884,348,5597,1.00875658947471e-20,0.467024942,0.396665797,0.549553479,1.14289512734236e-18,DB0012610011906_,41.31296705,-0.761372613,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,69933,DB00295,10000381,101,14562,90,9512,0.037280935,0.733067322,0.545602036,0.986229179,0.100130728,DB0029510000381_,2.301278663,-0.310517736,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,69936,DB00813,10000381,128,10444,339,9829,1.52507089457313e-25,0.355363683,0.287158688,0.437622614,2.43686859962642e-23,DB0081310000381_,52.06874328,-1.034613554,male,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,69939,DB00575,10008531,38,5206,16,3813,0.071858227,1.739400736,0.9453983,3.34683292,0.164529051,DB0057510008531_,1.804668123,0.553540649,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,69942,DB00813,10012373,74,10498,83,10085,0.337639472,0.856498687,0.616702879,1.187612663,0.506817609,DB0081310012373_,0.679604085,-0.154902495,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,69943,DB00297,10021097,73,1599,48,831,0.2394568,0.790470499,0.53611454,1.17442666,0.397298097,DB0029710021097_,0.923068407,-0.235126943,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,bupivacaine,DB00297
,69948,DB00295,10048010,66,14597,59,9543,0.082134606,0.731353805,0.506405033,1.058297205,0.181887032,DB0029510048010_,1.704369487,-0.312857935,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,69950,DB00575,10048010,36,5208,31,3798,0.535595861,0.846904589,0.508285623,1.418613392,0.692151661,DB0057510048010_,0.367950184,-0.166167236,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,69951,DB00813,10048010,83,10489,51,10117,0.0117742,1.569690911,1.093184047,2.273013209,0.040564238,DB0081310048010_,3.204868449,0.450878728,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,69957,DB00813,10057362,46,10526,30,10138,0.107515687,1.476779239,0.911641361,2.42526348,0.222436035,DB0081310057362_,1.503115703,0.389863526,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,69966,DB06290,10013709,33,329,124,549,5.71835847383994e-05,0.444410293,0.286077606,0.674937911,0.00049492,DB0629010013709_,7.611115433,-0.81100706,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,simeprevir,DB06290
,69967,DB06290,10019744,27,335,99,574,0.000650192,0.467613574,0.287388229,0.739399381,0.003851337,DB0629010019744_,5.559334826,-0.76011302,NA,10019744,Hepatitis C,10021881,Infections and infestations,Infec,simeprevir,DB06290
,69972,DB00722,10048334,90,25313,51,25981,0.00069009,1.811242724,1.27014303,2.607358607,0.004044375,DB0072210048334_,5.510428217,0.594013198,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,69980,DB00422,10061428,81,3354,67,2882,0.867629671,1.038823389,0.739228464,1.463861713,0.940671749,DB0042210061428_,0.061161032,0.038088716,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,methylphenidate,DB00422
,69982,DB00377,10003549,104,1015,57,666,0.311602973,1.197077536,0.845048037,1.709602717,0.479025691,DB0037710003549_,0.736001048,0.179883199,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,palonosetron,DB00377
,69984,DB00169,10005851,54,38637,47,18128,0.002590407,0.539046333,0.357676832,0.81501476,0.011996976,DB0016910005851_,4.42310066,-0.61795375,NA,10005851,Blood urea increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,69989,DB06769,10016256,24,643,30,1026,0.396464789,1.2763127,0.707201032,2.280991895,0.566027084,DB0676910016256_,0.56911335,0.243975217,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,bendamustine,DB06769
,69990,DB06769,10021097,21,646,39,1017,0.59157547,0.847806018,0.469275885,1.492381109,0.737872742,DB0676910021097_,0.303983906,-0.165103422,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,bendamustine,DB06769
,69997,DB00451,10033474,40,47231,12,15407,0.873356811,1.087348922,0.559089575,2.277453111,0.944873897,DB0045110033474_,0.056703802,0.083742552,NA,10033474,Pain of skin,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,70000,DB00377,10037660,67,1052,43,680,1,1.007158685,0.667774756,1.532665884,1,DB0037710037660_,0,0.007133183,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,palonosetron,DB00377
,70006,DB00451,10037868,40,47231,17,15402,0.357497521,0.767296252,0.425115058,1.443854643,0.527185746,DB0045110037868_,0.640202333,-0.264882304,NA,10037868,Rash maculo-papular,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,70009,DB00186,10037884,59,16842,36,9972,0.915455665,0.970352676,0.62997164,1.513445818,0.962143444,DB0018610037884_,0.03859173,-0.030095691,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,70011,DB00433,10037884,41,7615,33,5987,1,0.976802785,0.601742929,1.596614231,1,DB0043310037884_,0,-0.023470505,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,prochlorperazine,DB00433
,70012,DB00451,10037884,208,47063,60,15359,0.434545996,1.13134226,0.844628001,1.535053562,0.603064493,DB0045110037884_,0.505731134,0.123404768,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,70015,DB00169,10040844,144,38547,75,18100,0.468414797,0.901554516,0.67694468,1.209003197,0.634915581,DB0016910040844_,0.454263232,-0.103634766,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,70016,DB00186,10040844,47,16854,29,9979,0.905530813,0.959611993,0.591116651,1.582150631,0.957861963,DB0018610040844_,0.0430516,-0.04122625,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,70018,DB00433,10040844,44,7612,24,5996,0.177642714,1.444083382,0.858018289,2.485870124,0.320861621,DB0043310040844_,1.136745337,0.367474782,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,prochlorperazine,DB00433
,70019,DB00437,10040844,36,6885,41,11505,0.099013252,1.467157681,0.91011259,2.355878125,0.20937758,DB0043710040844_,1.563616053,0.383326979,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,70020,DB01234,10040844,128,31497,93,32795,0.008504264,1.433047745,1.088113416,1.893257388,0.031277518,DB0123410040844_,3.464855719,0.359803466,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,70036,DB00437,10042033,42,6879,39,11507,0.010885424,1.801309274,1.135709333,2.863306494,0.038093912,DB0043710042033_,3.267700806,0.588513775,NA,10042033,Stevens-Johnson syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,70040,DB00169,10043071,141,38550,79,18096,0.218242073,0.837836203,0.631274322,1.118642292,0.371418855,DB0016910043071_,0.990424864,-0.176932659,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,70042,DB00433,10043071,62,7594,47,5973,0.922899511,1.037568661,0.697643191,1.552023941,0.966266525,DB0043310043071_,0.034315577,0.03688015,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,prochlorperazine,DB00433
,70043,DB00437,10043071,57,6864,62,11484,0.022261534,1.538053362,1.05293539,2.243229755,0.067217791,DB0043710043071_,2.699817321,0.430517566,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,allopurinol,DB00437
,70044,DB01234,10043071,156,31469,147,32741,0.420100042,1.10411691,0.875220943,1.393483796,0.589031223,DB0123410043071_,0.529276087,0.099045839,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,70051,DB00437,10044223,55,6866,13,11533,2.7757079766107e-13,7.10588404,3.829049593,14.19218725,1.35110155861504e-11,DB0043710044223_,25.02751579,1.960923179,female,10044223,Toxic epidermal necrolysis,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,70064,DB00186,10068319,125,16776,46,9962,0.005330706,1.613625859,1.141121887,2.316806771,0.021528403,DB0018610068319_,3.838382154,0.478483733,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,70066,DB00433,10068319,46,7610,36,5984,1,1.004759564,0.63460116,1.602007989,1,DB0043310068319_,0,0.004748273,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,70067,DB01234,10068319,175,31450,123,32765,0.000902768,1.482235301,1.169593314,1.883307325,0.005064403,DB0123410068319_,5.285519028,0.393551287,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,70069,DB00281,10003553,80,11378,9,5662,6.58974397447241e-07,4.423664272,2.214833604,10.03186676,9.89214279663091e-06,DB0028110003553_,11.52376977,1.486968373,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,70070,DB00972,10003553,56,2448,6,1173,4.87326787156488e-05,4.471511103,1.922490915,12.73654619,0.000432457,DB0097210003553_,7.746027014,1.497726406,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azelastine,DB00972
,70071,DB13867,10003553,53,4497,22,2532,0.276227985,1.356363817,0.808711614,2.347834992,0.439666501,DB1386710003553_,0.821738793,0.304807455,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,70073,DB00471,10064355,74,14115,35,5430,0.33458698,0.813340548,0.536381186,1.254757529,0.50373903,DB0047110064355_,0.685696943,-0.206605379,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,70075,DB00281,10069327,345,11113,122,5549,0.000991819,1.411999068,1.142291267,1.754911637,0.005465399,DB0028110069327_,5.209318095,0.345006479,NA,10069327,Product quality issue,10077536,Product issues,Prod,lidocaine,DB00281
,70077,DB00559,10020751,57,9602,10,3296,0.048827635,1.956606564,0.988787963,4.302521401,0.122804936,DB0055910020751_,2.097158071,0.671211628,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,bosentan,DB00559
,70079,DB00682,10028164,38,19421,16,16348,0.019682414,1.999130285,1.087966868,3.841928365,0.061037312,DB0068210028164_,2.79626993,0.692712229,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,warfarin,DB00682
,70080,DB00820,10028164,43,11872,13,5803,0.153568636,1.616750554,0.852532279,3.279488176,0.288921114,DB0082010028164_,1.241601592,0.480418304,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,tadalafil,DB00820
,70082,DB00188,10053762,90,7796,103,8725,0.884992947,0.977908551,0.727431815,1.312622125,0.952079302,DB0018810053762_,0.049106947,-0.02233912,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,bortezomib,DB00188
,70088,DB01017,10053762,36,1433,31,870,0.162173544,0.705168508,0.420647174,1.188200696,0.300296035,DB0101710053762_,1.202986507,-0.349318487,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,minocycline,DB01017
,70089,DB01190,10053762,73,4861,63,2222,0.000364193,0.52969129,0.371446799,0.757192378,0.002370679,DB0119010053762_,6.044578991,-0.635460914,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,clindamycin,DB01190
,70090,DB00471,10042458,71,14118,29,5436,0.822974544,0.942684063,0.603314904,1.508134717,0.906059659,DB0047110042458_,0.098650126,-0.059024086,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,montelukast,DB00471
,70093,DB00471,10017955,57,14132,37,5428,0.015111352,0.591728181,0.38394798,0.92189643,0.049609928,DB0047110017955_,3.003564305,-0.524707904,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,70094,DB01020,10017955,42,1771,73,1805,0.005999347,0.586474659,0.389050781,0.874233534,0.023661615,DB0102010017955_,3.743901155,-0.533625818,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,isosorbide mononitrate,DB01020
,70095,DB01098,10017955,68,8081,122,7087,1.65127217204991e-06,0.488844306,0.35725593,0.664181239,2.24308470503007e-05,DB0109810017955_,10.70507345,-0.715711233,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,70121,DB00153,10009033,39,7384,11,3428,0.170228336,1.645898486,0.82543979,3.567500608,0.311147165,DB0015310009033_,1.167489279,0.498286427,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,70122,DB00697,10009033,41,6055,11,1795,0.869324669,1.104932911,0.556349572,2.388707899,0.941838249,DB0069710009033_,0.059921729,0.099784619,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tizanidine,DB00697
,70123,DB00814,10009033,37,8250,24,3391,0.089941562,0.633698621,0.368506075,1.109086515,0.195115253,DB0081410009033_,1.634164852,-0.456181799,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,meloxicam,DB00814
,70124,DB01050,10009033,57,18051,28,9343,0.908897759,1.053660799,0.658668436,1.721804312,0.95913476,DB0105010009033_,0.041723693,0.052270576,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,70126,DB00153,10013700,118,7305,12,3427,1.6281007605083e-09,4.613140755,2.53926377,9.194845149,4.33582862106997e-08,DB0015310013700_,16.95376801,1.528908917,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ergocalciferol,DB00153
,70127,DB01097,10013700,613,5652,81,1422,1.96027935021016e-08,1.903989636,1.496215786,2.448890372,4.1122061229269e-07,DB0109710013700_,14.704136,0.643951493,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,leflunomide,DB01097
,70128,DB00697,10019211,384,5712,65,1741,5.944474082977e-06,1.800604817,1.372997233,2.392758534,6.87419715226795e-05,DB0069710019211_,9.585150606,0.588122618,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,70138,DB00480,10016100,72,67356,52,67610,0.072639999,1.38982764,0.959269855,2.025828399,0.165899936,DB0048010016100_,1.796370466,0.329179739,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,70139,DB00758,10016100,16,8284,59,10015,2.12146407428252e-05,0.327882788,0.175935451,0.577869215,0.000210057,DB0075810016100_,8.468129556,-1.115099087,male,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,70140,DB01076,10016100,45,25702,59,25524,0.169989651,0.757436216,0.502009946,1.136015633,0.310893405,DB0107610016100_,1.168305174,-0.277815949,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,70154,DB00887,10013573,101,2240,68,1747,0.384183401,1.158350317,0.837662306,1.610056205,0.554235619,DB0088710013573_,0.590165378,0.146996853,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,bumetanide,DB00887
,70155,DB00887,10016807,145,2196,73,1742,0.001969964,1.575483964,1.172327518,2.132320132,0.009615695,DB0088710016807_,4.644358659,0.454562504,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,bumetanide,DB00887
,70156,DB00887,10030124,125,2216,63,1752,0.004169518,1.568510344,1.141662476,2.172956127,0.017665343,DB0088710030124_,4.036150596,0.450126343,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,70157,DB00203,10040979,39,13839,39,8899,0.062306968,0.643070942,0.401450755,1.029988088,0.147757007,DB0020310040979_,1.912186198,-0.441500231,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,70159,DB00421,10040979,36,8867,15,5237,0.309731657,1.417447112,0.756054707,2.78951569,0.477187539,DB0042110040979_,0.739845701,0.348857445,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,70161,DB00887,10047899,98,2243,52,1763,0.023688385,1.481170728,1.041125888,2.127873009,0.070519192,DB0088710047899_,2.651870372,0.392832808,NA,10047899,Weight increased,10022891,Investigations,Inv,bumetanide,DB00887
,70162,DB00887,10053762,35,2306,30,1785,0.706596899,0.903102042,0.53634905,1.529170574,0.824363048,DB0088710053762_,0.193144254,-0.101919728,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,bumetanide,DB00887
,70164,DB00678,10039203,44,15555,23,10701,0.320315325,1.31605657,0.777132562,2.284842888,0.488511072,DB0067810039203_,0.716393142,0.274639818,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,70166,DB08932,10039203,66,19377,29,6568,0.239018249,0.771431194,0.490944786,1.239631581,0.396751266,DB0893210039203_,0.924445728,-0.259507796,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,70175,DB00465,10053762,53,2051,27,856,0.456057608,0.819338145,0.502351575,1.364454614,0.623406014,DB0046510053762_,0.472557265,-0.199258405,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ketorolac,DB00465
,70182,DB08868,10051290,252,8950,64,2447,0.676679784,1.076528382,0.812032498,1.444905578,0.803963008,DB0886810051290_,0.218202021,0.073741403,NA,10051290,Central nervous system lesion,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,70187,DB00175,10017577,142,7989,82,6024,0.05691868,1.30574598,0.985859603,1.738943583,0.137649049,DB0017510017577_,1.983047954,0.266774509,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,70189,DB00264,10047461,67,29540,45,24847,0.255618855,1.252343756,0.84535899,1.870692614,0.416381595,DB0026410047461_,0.876153144,0.225016801,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,70190,DB00381,10047461,84,29276,36,22851,0.002268474,1.821219664,1.218271917,2.772397155,0.010779508,DB0038110047461_,4.530108356,0.599506422,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,70192,DB00175,10047571,61,8070,30,6076,0.056361906,1.530874917,0.972094919,2.458733884,0.136749221,DB0017510047571_,1.989606532,0.425839413,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,pravastatin,DB00175
,70193,DB00381,10047571,196,29164,88,22799,1.08662989942073e-05,1.741145581,1.346387589,2.266627685,0.00011658,DB0038110047571_,9.056933984,0.554543276,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,amlodipine,DB00381
,70195,DB00381,10047943,67,29293,59,22828,0.529491956,0.884969784,0.614032971,1.278308587,0.686784904,DB0038110047943_,0.375734131,-0.122201777,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,amlodipine,DB00381
,70196,DB08908,10047943,44,10629,11,3268,0.634029482,1.229820642,0.624070757,2.64362732,0.772401818,DB0890810047943_,0.258250375,0.206868339,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,dimethyl fumarate,DB08908
,70197,DB00175,10049848,66,8065,58,6048,0.412357586,0.853354695,0.589558514,1.238086973,0.581762608,DB0017510049848_,0.541692805,-0.158579998,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,70198,DB00175,10060795,32,8099,22,6084,0.78455299,1.092678059,0.614769165,1.975840749,0.883016842,DB0017510060795_,0.124411004,0.088631618,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,pravastatin,DB00175
,70199,DB00381,10060795,83,29277,60,22827,0.673958852,1.078590771,0.764115977,1.530247158,0.802273829,DB0038110060795_,0.220305297,0.075655347,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,amlodipine,DB00381
,70201,DB00586,10008190,48,7061,12,2793,0.194898524,1.582193351,0.82634403,3.277182865,0.342875825,DB0058610008190_,1.070386924,0.458812081,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,70202,DB01115,10008190,44,3556,25,2243,0.710964612,1.110147074,0.662537054,1.898467747,0.827658657,DB0111510008190_,0.189154459,0.104492505,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,nifedipine,DB01115
,70203,DB01409,10008190,43,5988,53,3913,0.002237851,0.530228014,0.345423222,0.809826851,0.010657828,DB0140910008190_,4.541460666,-0.634448151,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,tiotropium,DB01409
,70205,DB00758,10017955,358,7942,548,9526,0.000474025,0.78359105,0.681621054,0.899915202,0.002954431,DB0075810017955_,5.824449063,-0.243868015,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,70207,DB01069,10003549,247,6453,80,2315,0.481807473,1.10762018,0.85335892,1.450382289,0.646303109,DB0106910003549_,0.436486676,0.102213732,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,70209,DB01069,10003658,48,6652,29,2366,0.02714493,0.588754551,0.362859011,0.970692607,0.078329302,DB0106910003658_,2.546833523,-0.529745904,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,promethazine,DB01069
,70210,DB01175,10003658,82,10642,58,4834,0.013124037,0.642214968,0.452433687,0.916737629,0.044226322,DB0117510003658_,3.118435156,-0.44283219,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,escitalopram,DB01175
,70211,DB01611,10003658,46,11867,21,2340,0.002540679,0.431962435,0.252051933,0.763565057,0.01180724,DB0161110003658_,4.439042412,-0.839416651,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,hydroxychloroquine,DB01611
,70212,DB00425,10010264,203,12492,86,7398,0.00988352,1.397889957,1.079203909,1.823472644,0.035227922,DB0042510010264_,3.345916274,0.334963926,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,70213,DB00557,10010264,126,5861,58,3009,0.529528132,1.115284147,0.80820009,1.554595015,0.68681488,DB0055710010264_,0.375690484,0.109109213,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,70214,DB00843,10010264,22,2172,44,2129,0.006130265,0.490181627,0.278782031,0.83890454,0.024076804,DB0084310010264_,3.726506378,-0.71297929,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,donepezil,DB00843
,70215,DB00958,10010264,32,4562,20,2565,0.772143503,0.89962147,0.497792322,1.663345413,0.875252473,DB0095810010264_,0.133242894,-0.105781194,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,70216,DB01069,10010264,146,6554,26,2369,0.000452254,2.029631076,1.326607714,3.219116397,0.002841006,DB0106910010264_,5.863597038,0.70785404,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,70217,DB01175,10010264,206,10518,71,4821,0.042560446,1.329905585,1.008433663,1.771078239,0.110828346,DB0117510010264_,2.199772703,0.285107951,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,70218,DB00451,10024384,56,47215,14,15405,0.408277279,1.305076547,0.716743376,2.539673055,0.577693824,DB0045110024384_,0.548711266,0.266261696,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,levothyroxine,DB00451
,70223,DB01611,10024384,67,11846,12,2349,0.879436372,1.107110298,0.592722939,2.25265697,0.949360756,DB0161110024384_,0.05196641,0.101753286,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,hydroxychloroquine,DB01611
,70224,DB00451,10029366,133,47138,54,15365,0.174148553,0.802818308,0.580658214,1.123542957,0.316350524,DB0045110029366_,1.150904427,-0.219626857,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,70245,DB00425,10043554,80,12615,56,7428,0.328121414,0.841189953,0.589657289,1.20719254,0.49669842,DB0042510043554_,0.699772238,-0.172937779,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,zolpidem,DB00425
,70247,DB00958,10043554,153,4441,91,2494,0.684155076,0.944211857,0.720159645,1.243746857,0.809098181,DB0095810043554_,0.211835008,-0.057404714,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,carboplatin,DB00958
,70248,DB01611,10043554,42,11871,14,2347,0.102651878,0.593153277,0.31691854,1.177932142,0.214996383,DB0161110043554_,1.537134073,-0.522302436,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,hydroxychloroquine,DB01611
,70268,DB00635,10060945,56,32997,33,23761,0.390822381,1.22197468,0.780741177,1.940471336,0.56068414,DB0063510060945_,0.578597563,0.20046814,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,70334,DB00695,10002906,35,28014,19,20509,0.335665416,1.348592816,0.750338468,2.496322868,0.504834564,DB0069510002906_,0.6835245,0.299061691,NA,10002906,Aortic stenosis,10047065,Vascular disorders,Vasc,furosemide,DB00695
,70358,DB00455,10007559,63,9338,48,5070,0.089547657,0.712658534,0.480994887,1.061775469,0.194509559,DB0045510007559_,1.637273971,-0.338752887,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,loratadine,DB00455
,70359,DB00472,10007559,62,10697,22,4290,0.716721853,1.130211268,0.684023684,1.933463511,0.83251017,DB0047210007559_,0.183309841,0.122404578,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,fluoxetine,DB00472
,70362,DB01065,10007559,35,4296,34,3017,0.179273908,0.722980703,0.436796454,1.197747794,0.322965549,DB0106510007559_,1.13020962,-0.324372747,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,melatonin,DB01065
,70365,DB00321,10008479,83,7364,30,2820,0.833264185,1.059472352,0.688459382,1.670654099,0.913378057,DB0032110008479_,0.090605402,0.057771003,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,70366,DB00332,10008479,75,2609,37,1619,0.279285171,1.257776442,0.833078053,1.928298353,0.443123817,DB0033210008479_,0.813906052,0.229345433,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ipratropium,DB00332
,70369,DB00472,10008479,117,10642,46,4266,1,1.019598016,0.717638693,1.469902595,1,DB0047210008479_,0,0.019408448,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,70370,DB00557,10008479,76,5911,40,3027,0.921416725,0.972963839,0.653265351,1.468643677,0.965244749,DB0055710008479_,0.035373584,-0.027408362,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,70372,DB01065,10008479,62,4269,28,3023,0.052374485,1.567905063,0.985655456,2.551429015,0.129476919,DB0106510008479_,2.044252644,0.449740373,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,70374,DB00215,10028596,55,11048,40,5236,0.046877563,0.651664874,0.425212277,1.006547491,0.119217913,DB0021510028596_,2.126802255,-0.428224846,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,citalopram,DB00215
,70376,DB00321,10028596,30,7417,20,2830,0.057383556,0.572378267,0.313869426,1.065234859,0.138506563,DB0032110028596_,1.976837567,-0.557955201,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,amitriptyline,DB00321
,70413,DB00222,10048959,57,3149,52,3076,0.772193059,1.070763184,0.719716226,1.59594256,0.875289774,DB0022210048959_,0.133200278,0.068371651,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,70414,DB00181,10038695,93,9763,89,5782,0.001514295,0.618900123,0.456890649,0.838718323,0.007755138,DB0018110038695_,4.859399641,-0.479811371,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,baclofen,DB00181
,70433,DB08880,10016256,264,3074,71,738,0.428896398,0.892693318,0.675482583,1.191764998,0.597400341,DB0888010016256_,0.515167803,-0.113512186,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,teriflunomide,DB08880
,70434,DB08880,10047700,91,3247,12,797,0.043406125,1.861115839,1.008939171,3.752867187,0.112446294,DB0888010047700_,2.185279562,0.621176221,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,teriflunomide,DB08880
,70438,DB00273,10010264,200,8281,56,2137,0.584045726,0.921640582,0.679310656,1.267800358,0.731954224,DB0027310010264_,0.312037303,-0.081599956,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,70439,DB00313,10010264,19,1220,36,1481,0.132532912,0.640789195,0.345313049,1.153921142,0.259314248,DB0031310010264_,1.349714641,-0.445054745,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,valproic acid,DB00313
,70441,DB00321,10010264,149,7298,49,2801,0.378309081,1.167053887,0.837159763,1.651430198,0.548323915,DB0032110010264_,0.600889081,0.154482528,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,70444,DB00669,10010264,107,6270,7,1090,0.007151166,2.657088192,1.241368225,6.786047521,0.027243772,DB0066910010264_,3.602930347,0.977230859,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,70445,DB00697,10010264,158,5938,34,1772,0.097851214,1.38668974,0.948293679,2.080520822,0.207663733,DB0069710010264_,1.571835176,0.326919425,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,70447,DB00813,10010264,109,10463,62,10106,0.000907197,1.698027402,1.230432397,2.361421579,0.005085994,DB0081310010264_,5.281264861,0.529467226,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,70448,DB00818,10010264,26,1394,30,1647,1,1.023958422,0.578692295,1.800754953,1,DB0081810010264_,0,0.023675923,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,propofol,DB00818
,70449,DB00829,10010264,129,7923,57,4397,0.165214914,1.255988943,0.910583431,1.750959885,0.304419643,DB0082910010264_,1.189348125,0.227923265,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,70450,DB00996,10010264,721,38232,267,22158,1.75787540799685e-10,1.565036112,1.356753124,1.809558559,5.53031180122048e-09,DB0099610010264_,19.01302164,0.447908898,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,70455,DB00313,10013709,121,1118,127,1390,0.204468292,1.184476377,0.904017181,1.551391781,0.354472754,DB0031310013709_,1.037123794,0.169300801,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,valproic acid,DB00313
,70457,DB00321,10013709,395,7052,136,2714,0.295643877,1.11776347,0.912703987,1.375440772,0.461474468,DB0032110013709_,0.773328551,0.111329787,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,70458,DB00465,10013709,104,2000,30,853,0.065843969,1.478354507,0.967952725,2.318227393,0.153854452,DB0046510013709_,1.871748238,0.39092965,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ketorolac,DB00465
,70459,DB00470,10013709,31,888,32,921,1,1.004748501,0.587465104,1.716414248,1,DB0047010013709_,0,0.004737262,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dronabinol,DB00470
,70460,DB00540,10013709,157,2326,59,1032,0.321850665,1.180570459,0.86148979,1.635681459,0.490156078,DB0054010013709_,0.713031411,0.165997762,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,nortriptyline,DB00540
,70461,DB00564,10013709,201,2403,112,1351,1,1.008971116,0.788843641,1.295523094,1,DB0056410013709_,0,0.008931114,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,carbamazepine,DB00564
,70463,DB00818,10013709,156,1264,164,1513,0.286408438,1.138554085,0.896798892,1.445052452,0.451144351,DB0081810013709_,0.795967922,0.129759111,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,propofol,DB00818
,70489,DB01202,10028622,36,6678,21,5697,0.183803177,1.46240954,0.829924167,2.639796848,0.328724672,DB0120210028622_,1.11253474,0.380085445,NA,10028622,Myoclonus,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,70499,DB00313,10067327,51,1188,68,1449,0.706494512,0.914772488,0.618220018,1.346455893,0.824280184,DB0031310067327_,0.193244778,-0.089079891,NA,10067327,Hyperammonaemic encephalopathy,10029205,Nervous system disorders,Nerv,valproic acid,DB00313
,70533,DB01222,10012601,33,9241,25,5380,0.34080289,0.768518861,0.442751056,1.349603179,0.510049762,DB0122210012601_,0.673246986,-0.263290173,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,budesonide,DB01222
,70534,DB06605,10050953,21,14052,41,12992,0.004878805,0.473574251,0.265688273,0.820652008,0.020064052,DB0660510050953_,3.908825521,-0.747446565,NA,10050953,Lower gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,70536,DB00215,10005191,39,11064,18,5258,1,1.02970287,0.574556021,1.914149623,1,DB0021510005191_,0,0.029270285,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,citalopram,DB00215
,70537,DB00341,10005191,57,11348,21,5047,0.539010618,1.20714405,0.719671085,2.098914447,0.694845223,DB0034110005191_,0.36406616,0.188257281,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,cetirizine,DB00341
,70538,DB00471,10005191,59,14130,14,5451,0.115896341,1.625784184,0.895835618,3.155921263,0.235029535,DB0047110005191_,1.448044093,0.485990274,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,70539,DB00497,10005191,67,19200,33,16342,0.011629104,1.728053392,1.122239385,2.708432767,0.0401591,DB0049710005191_,3.214906214,0.546995568,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,70540,DB00787,10005191,59,16941,32,17216,0.004359306,1.8736336,1.197924954,2.979443977,0.018310062,DB0078710005191_,4.000304553,0.627879647,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,70542,DB11089,10005191,32,10143,19,8388,0.263455991,1.392772059,0.765142807,2.602731261,0.425260422,DB1108910005191_,0.855053539,0.331296048,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,docusate,DB11089
,70543,DB00181,10020751,95,9761,26,5845,0.000211739,2.187864874,1.403368133,3.522967197,0.001511151,DB0018110020751_,6.49488382,0.782926125,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,baclofen,DB00181
,70544,DB00213,10020751,161,18734,78,13343,0.005550761,1.470106567,1.1139345,1.954019141,0.022239426,DB0021310020751_,3.805888629,0.385334893,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,pantoprazole,DB00213
,70545,DB00215,10020751,102,11001,28,5248,0.008212556,1.73776332,1.132725164,2.746756364,0.030425232,DB0021510020751_,3.492483009,0.552598838,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,citalopram,DB00215
,70547,DB00787,10020751,145,16855,76,17172,1.92873731383511e-06,1.943728226,1.461418971,2.602867604,2.56627994402206e-05,DB0078710020751_,10.57046811,0.664607895,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,acyclovir,DB00787
,70548,DB00836,10020751,41,5494,17,4058,0.045781283,1.781278447,0.988235911,3.349185681,0.117058465,DB0083610020751_,2.145081771,0.577331335,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,loperamide,DB00836
,70549,DB11089,10020751,100,10075,40,8367,5.56998447335768e-05,2.076062414,1.423516298,3.079334534,0.00048399,DB1108910020751_,7.633445856,0.73047303,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,docusate,DB11089
,70551,DB00213,10040831,35,18860,22,13399,0.688635377,1.130287059,0.644396282,2.023504133,0.812313463,DB0021310040831_,0.207868975,0.122471635,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,70553,DB00341,10040831,41,11364,9,5059,0.064093603,2.027957485,0.969954488,4.749307668,0.150823667,DB0034110040831_,1.891643891,0.707029121,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,cetirizine,DB00341
,70554,DB00404,10040831,43,19849,12,9850,0.085052593,1.778186015,0.920635081,3.706016102,0.186861201,DB0040410040831_,1.677389179,0.575593752,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,70556,DB00787,10040831,32,16968,20,17228,0.096138443,1.624483668,0.900626373,2.998382377,0.204972135,DB0078710040831_,1.584881237,0.485190022,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,70558,DB00996,10040831,51,38902,35,22390,0.43399925,0.838667238,0.534699649,1.329143704,0.602512493,DB0099610040831_,0.506646879,-0.175941269,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,70603,DB01012,10000059,252,10380,167,8518,0.036947474,1.238281037,1.012058292,1.518265625,0.099484158,DB0101210000059_,2.307756862,0.213724157,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,cinacalcet,DB01012
,70605,DB00927,10042682,41,7456,15,5001,0.05468582,1.833255285,0.992243672,3.569595385,0.133806543,DB0092710042682_,2.011360233,0.606093231,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,70619,DB01076,10007636,21,25726,34,25549,0.080380442,0.61340707,0.338200196,1.088097382,0.179044346,DB0107610007636_,1.720121761,-0.488726502,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,70631,DB00331,10047302,21,24925,41,20711,0.001261306,0.425605367,0.238847406,0.73735146,0.006657314,DB0033110047302_,5.012039139,-0.854242731,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,metformin,DB00331
,70632,DB00381,10027091,53,29307,32,22855,0.274903048,1.291615603,0.817264047,2.071059174,0.438128036,DB0038110027091_,0.825244092,0.25589384,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,70635,DB00480,10041569,244,67184,169,67493,0.000211156,1.450416301,1.186844485,1.775902763,0.001508148,DB0048010041569_,6.496872972,0.371850619,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,70636,DB00531,10020937,45,7207,27,6489,0.098640578,1.50057613,0.909963657,2.518075622,0.20884153,DB0053110020937_,1.566179544,0.405849121,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,70642,DB00531,10000060,35,7217,22,6494,0.231327974,1.431490858,0.815581312,2.564447323,0.387537017,DB0053110000060_,0.947943907,0.358716459,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,70643,DB00537,10000060,41,7516,32,4266,0.180804672,0.727267181,0.446143589,1.195020465,0.324876153,DB0053710000060_,1.124311237,-0.318461357,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,ciprofloxacin,DB00537
,70646,DB00635,10000060,250,32803,109,23685,7.74721785285282e-06,1.656031078,1.316377352,2.094597071,8.68382180222757e-05,DB0063510000060_,9.351463733,0.504423823,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,70647,DB00688,10000060,41,6449,18,5360,0.025276231,1.893023106,1.06206981,3.504972136,0.074107058,DB0068810000060_,2.602244503,0.638175078,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,mycophenolate mofetil,DB00688
,70648,DB01104,10000060,89,15374,32,7254,0.204660952,1.312329133,0.866273744,2.033886263,0.354669371,DB0110410000060_,1.036569272,0.271803523,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,70650,DB01136,10000060,66,9818,58,11057,0.17658062,1.281513648,0.885878222,1.858197859,0.319470117,DB0113610000060_,1.141091539,0.248041917,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,70652,DB01306,10000060,33,4175,26,3840,0.602144678,1.167365241,0.675736798,2.036530721,0.746241313,DB0130610000060_,0.292706255,0.154749279,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,insulin aspart,DB01306
,70657,DB00316,10000084,103,65371,42,36911,0.083256127,1.384704981,0.958139043,2.03315072,0.183874914,DB0031610000084_,1.693499569,0.325487107,NA,10000084,Abdominal pain lower,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,70663,DB00695,10000084,32,28017,20,20508,0.674002427,1.17115041,0.649395279,2.161395615,0.802282079,DB0069510000084_,0.220295013,0.157986523,NA,10000084,Abdominal pain lower,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,70676,DB00531,10000087,32,7220,26,6490,0.792444734,1.106297597,0.638042098,1.93507027,0.887531177,DB0053110000087_,0.119311629,0.101018942,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,70677,DB00537,10000087,92,7465,29,4269,0.004257245,1.814120048,1.181428878,2.862261941,0.017974732,DB0053710000087_,4.018788274,0.595600528,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ciprofloxacin,DB00537
,70679,DB00688,10000087,66,6424,30,5348,0.005354748,1.831413377,1.17054834,2.926154876,0.021605582,DB0068810000087_,3.834803572,0.605088006,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,mycophenolate mofetil,DB00688
,70680,DB01115,10000087,56,3544,20,2248,0.032125131,1.775909145,1.045868822,3.133568913,0.089379102,DB0111510000087_,2.414868387,0.574312486,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,nifedipine,DB01115
,70681,DB01190,10000087,47,4887,11,2274,0.046037174,1.988005402,1.013882068,4.258715134,0.117546953,DB0119010000087_,2.140917427,0.687131826,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,clindamycin,DB01190
,70682,DB01306,10000087,62,4146,32,3834,0.006884986,1.791563892,1.148449179,2.843864046,0.026454008,DB0130610000087_,3.632347617,0.583088921,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,insulin aspart,DB01306
,70688,DB00537,10005557,25,7532,30,4268,0.006980112,0.472230581,0.265906014,0.831876343,0.026729023,DB0053710005557_,3.622005318,-0.750287894,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,ciprofloxacin,DB00537
,70689,DB00575,10005557,49,5195,24,3805,0.12177493,1.495322727,0.89819191,2.552943249,0.243945009,DB0057510005557_,1.410812452,0.402342055,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,clonidine,DB00575
,70692,DB00864,10005557,34,6835,37,8355,0.6344269,1.123262726,0.68313925,1.841833747,0.772713667,DB0086410005557_,0.257846716,0.116237599,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,tacrolimus,DB00864
,70693,DB00959,10005557,66,8012,39,4963,0.840977952,1.048293499,0.693975398,1.602509791,0.918787375,DB0095910005557_,0.084700549,0.047163603,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,methylprednisolone,DB00959
,70718,DB00688,10010774,56,6434,25,5353,0.009674774,1.863533166,1.14197619,3.121219056,0.034664863,DB0068810010774_,3.362028687,0.622474238,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,mycophenolate mofetil,DB00688
,70719,DB00959,10010774,105,7973,59,4943,0.572269093,1.103340982,0.792886758,1.547802287,0.722292051,DB0095910010774_,0.325325719,0.098342833,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,70720,DB01115,10010774,91,3509,62,2206,0.674165246,0.922737722,0.657816527,1.301597403,0.80236002,DB0111510010774_,0.22019787,-0.080410243,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,nifedipine,DB01115
,70721,DB01190,10010774,50,4884,40,2245,0.011681485,0.574619872,0.370357538,0.896647661,0.040300281,DB0119010010774_,3.21139684,-0.554046549,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,clindamycin,DB01190
,70722,DB11074,10010774,43,1217,27,841,0.804851732,1.100526433,0.658808495,1.867824863,0.894427482,DB1107410010774_,0.11157145,0.09578864,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,dimethicone,DB11074
,70723,DB00250,10012735,37,789,32,778,0.624197709,1.140037886,0.683251585,1.911516144,0.764077529,DB0025010012735_,0.269086018,0.131061495,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dapsone,DB00250
,70724,DB00598,10012735,61,1527,40,988,1,0.98670746,0.645882484,1.521852111,1,DB0059810012735_,0,-0.013381676,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,labetalol,DB00598
,70725,DB01115,10012735,246,3354,95,2173,2.08479538414012e-05,1.677533458,1.310096588,2.162384333,0.000207022,DB0111510012735_,8.482683241,0.517324535,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,nifedipine,DB01115
,70726,DB11074,10012735,127,1133,71,797,0.149292492,1.258135567,0.919826548,1.731633685,0.282995215,DB1107410012735_,1.262325289,0.229630916,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dimethicone,DB11074
,70729,DB00316,10016165,55,65419,71,36882,4.07873181015033e-06,0.436730656,0.301342593,0.630065082,4.93825267755879e-05,DB0031610016165_,9.915913905,-0.828438621,NA,10016165,Failure to thrive,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,70732,DB00635,10016165,20,33033,46,23748,7.37358645782692e-06,0.312578829,0.175100322,0.539242949,8.30575187675083e-05,DB0063510016165_,9.395977193,-1.162898588,male,10016165,Failure to thrive,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,70734,DB00695,10016165,27,28022,36,20492,0.020983322,0.548480647,0.320169137,0.929274173,0.064207016,DB0069510016165_,2.745642785,-0.600603283,NA,10016165,Failure to thrive,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,70762,DB00213,10017853,83,18812,30,13391,0.00108401,1.969355117,1.282186156,3.100011149,0.005887023,DB0021310017853_,5.135004806,0.677706137,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,70768,DB00635,10017853,63,32990,45,23749,1,1.007838795,0.676378185,1.512601797,1,DB0063510017853_,0,0.007808231,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,70770,DB00695,10017853,57,27992,34,20494,0.395707853,1.2274018,0.788645533,1.936701839,0.565389118,DB0069510017853_,0.57024108,0.204899577,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,70799,DB00537,10017885,52,7505,8,4290,0.000120164,3.715202068,1.750450281,9.065022267,0.000932536,DB0053710017885_,6.977602561,1.312433069,female,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,ciprofloxacin,DB00537
,70803,DB00959,10017885,50,8028,12,4990,0.002294438,2.589723855,1.358204185,5.34776172,0.010878943,DB0095910017885_,4.52092619,0.95155125,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,70804,DB01075,10017885,78,19870,26,11071,0.023779199,1.671488664,1.059510967,2.717085975,0.070732744,DB0107510017885_,2.648846669,0.513714645,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,70806,DB01136,10017885,56,9828,40,11075,0.03101286,1.577585862,1.031824545,2.431932723,0.086951789,DB0113610017885_,2.442401466,0.455895743,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,70810,DB11089,10017885,67,10108,34,8373,0.020872334,1.632298627,1.063728727,2.546773264,0.06392046,DB1108910017885_,2.750115789,0.489989222,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,70811,DB00213,10018830,49,18846,48,13373,0.121772351,0.724395302,0.476184963,1.102546263,0.243945009,DB0021310018830_,1.410812452,-0.322418038,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,70829,DB00213,10018852,31,18864,32,13389,0.158887865,0.687605621,0.405562174,1.164299732,0.296007337,DB0021310018852_,1.217371037,-0.37453983,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,pantoprazole,DB00213
,70839,DB01136,10018852,23,9861,35,11080,0.292739108,0.738389844,0.416243961,1.286429666,0.458328466,DB0113610018852_,0.780169176,-0.303283349,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,carvedilol,DB01136
,70845,DB00537,10019211,271,7286,58,4240,7.07470892071221e-14,2.718843749,2.035212717,3.685110324,3.70067112399841e-12,DB0053710019211_,26.32250693,1.000206698,female,10019211,Headache,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,70846,DB01115,10019211,217,3383,59,2209,5.30918613111602e-10,2.401268347,1.783437366,3.275698736,1.55316591492915e-08,DB0111510019211_,17.98038537,0.875997076,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,nifedipine,DB01115
,70847,DB11074,10019211,59,1201,25,843,0.041048802,1.656143607,1.011727563,2.783615666,0.107751313,DB1107410019211_,2.227929369,0.504491771,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,dimethicone,DB11074
,70848,DB00213,10020028,61,18834,15,13406,9.26535289331346e-05,2.89451695,1.624501384,5.486925317,0.000747443,DB0021310020028_,7.19885314,1.062818241,female,10020028,Hiatus hernia,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,70851,DB00316,10020028,82,65392,23,36930,0.002168669,2.013434699,1.254824657,3.351790047,0.010399245,DB0031610020028_,4.566022044,0.699842069,NA,10020028,Hiatus hernia,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,70857,DB00635,10020028,49,33004,12,23782,0.000369887,2.942269232,1.542020839,6.079137045,0.002402395,DB0063510020028_,6.031289327,1.079181131,female,10020028,Hiatus hernia,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,70859,DB00695,10020028,46,28003,14,20514,0.00253899,2.40693117,1.299728544,4.742245549,0.011802523,DB0069510020028_,4.439441979,0.878352563,NA,10020028,Hiatus hernia,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,70873,DB01115,10020772,82,3518,51,2217,1,1.01324095,0.702702918,1.47297839,1,DB0111510020772_,0,0.013154055,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,nifedipine,DB01115
,70875,DB00213,10020947,26,18869,34,13387,0.01846494,0.542559751,0.312466125,0.931764207,0.058004295,DB0021310020947_,2.847238212,-0.61145706,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,70883,DB00635,10020947,24,33029,52,23742,3.5987571976029e-06,0.331770314,0.195532938,0.54812205,4.43475541204839e-05,DB0063510020947_,10.023453,-1.103312373,male,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,70885,DB00695,10020947,57,27992,37,20491,0.602472369,1.127681856,0.732424201,1.755447693,0.746381968,DB0069510020947_,0.292517788,0.120164071,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,70899,DB00531,10021015,73,7179,38,6478,0.005565366,1.733395918,1.153921998,2.641479535,0.022289446,DB0053110021015_,3.803641988,0.550082443,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,cyclophosphamide,DB00531
,70902,DB00635,10021015,127,32926,97,23697,0.684090324,0.942307611,0.717349358,1.241039238,0.809059034,DB0063510021015_,0.211883393,-0.059423507,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,70904,DB00959,10021015,30,8048,30,4972,0.063319414,0.61784045,0.359353499,1.062180968,0.149517207,DB0095910021015_,1.900343799,-0.481525027,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,methylprednisolone,DB00959
,70905,DB01075,10021015,81,19867,33,11064,0.142169802,1.366931513,0.900820824,2.117372765,0.272818635,DB0107510021015_,1.298948046,0.312568456,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,diphenhydramine,DB01075
,70922,DB00864,10023421,23,6846,35,8357,0.430846884,0.802194819,0.452054959,1.398079804,0.59929144,DB0086410023421_,0.512007256,-0.220403784,NA,10023421,Kidney fibrosis,10038359,Renal and urinary disorders,Renal,tacrolimus,DB00864
,70933,DB00213,10025482,629,18266,218,13203,3.1538339840286e-22,2.085499674,1.781924687,2.448037798,4.07363765455488e-20,DB0021310025482_,44.64716549,0.735008478,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,70936,DB00537,10025482,147,7410,75,4223,0.481103976,1.117021627,0.83785763,1.49955375,0.645738402,DB0053710025482_,0.437360807,0.110665881,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,70937,DB00575,10025482,158,5086,82,3747,0.011701051,1.419494786,1.076514836,1.883299722,0.0403466,DB0057510025482_,3.210248149,0.350301024,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,70939,DB00688,10025482,122,6368,55,5323,0.000129689,1.854077548,1.334939761,2.603185568,0.000995434,DB0068810025482_,6.912331548,0.617387294,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,70940,DB00864,10025482,75,6794,70,8322,0.111088914,1.312364719,0.933226918,1.847463886,0.227718712,DB0086410025482_,1.479644132,0.271830639,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,70941,DB01190,10025482,91,4843,32,2253,0.203529901,1.322931745,0.872446556,2.052539693,0.353330918,DB0119010025482_,1.040350215,0.279850293,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,clindamycin,DB01190
,70943,DB11074,10025482,42,1218,14,854,0.018375305,2.102765843,1.117317531,4.196135293,0.057791792,DB1107410025482_,2.850908524,0.743253546,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,dimethicone,DB11074
,70944,DB11089,10025482,293,9882,133,8274,2.75936944287161e-09,1.844470524,1.494327018,2.286417933,7.0212996907919e-08,DB1108910025482_,16.4717324,0.612192257,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,70945,DB00250,10028813,31,795,34,776,0.704712588,0.89003802,0.523350151,1.508744729,0.822904333,DB0025010028813_,0.194915327,-0.116491098,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dapsone,DB00250
,70946,DB00598,10028813,71,1517,22,1006,0.001596504,2.139596749,1.30034326,3.650701699,0.00808401,DB0059810028813_,4.817867218,0.760617376,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,labetalol,DB00598
,70947,DB11074,10028813,105,1155,48,820,0.016560843,1.552719904,1.079604771,2.25982096,0.053244665,DB1107410028813_,2.932857658,0.44000817,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dimethicone,DB11074
,70949,DB00257,10033371,55,897,13,609,0.000329111,2.870692372,1.531870767,5.778752175,0.002177091,DB0025710033371_,6.129765805,1.054553245,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,clotrimazole,DB00257
,70950,DB00598,10033371,47,1541,11,1017,0.001011415,2.818851204,1.43250057,6.056789826,0.005555912,DB0059810033371_,5.192892745,1.036329427,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,labetalol,DB00598
,70951,DB00688,10033371,103,6387,37,5341,4.7636683872908e-06,2.327664574,1.581513662,3.493311622,5.66702980583565e-05,DB0068810033371_,9.778260328,0.844865436,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,70952,DB00959,10033371,336,7742,122,4880,1.11567330360128e-07,1.735914178,1.402411917,2.160139715,2.00447524163771e-06,DB0095910033371_,13.12012826,0.551534178,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,70953,DB01115,10033371,128,3472,40,2228,5.1244407157031e-05,2.053221147,1.423127927,3.019053526,0.000451394,DB0111510033371_,7.703170323,0.719409851,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,70955,DB11074,10033371,47,1213,17,851,0.019820351,1.93905731,1.08418357,3.627794445,0.061334815,DB1107410033371_,2.791407653,0.662201932,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,dimethicone,DB11074
,70957,DB00537,10037660,162,7395,150,4148,1.59792143001951e-05,0.605790747,0.480515405,0.764209587,0.00016362,DB0053710037660_,8.717961254,-0.501220654,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,70958,DB00575,10037660,83,5161,72,3757,0.287110006,0.83919584,0.602820921,1.170601609,0.451924457,DB0057510037660_,0.794240244,-0.175311179,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,70960,DB01115,10037660,50,3550,45,2223,0.088975033,0.695838664,0.454064982,1.068986746,0.193561659,DB0111510037660_,1.642159167,-0.362637451,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,70961,DB01190,10037660,86,4848,56,2229,0.055193268,0.706108373,0.496557964,1.011047875,0.134672087,DB0119010037660_,2.004912438,-0.34798655,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,clindamycin,DB01190
,70964,DB00537,10038435,81,7476,52,4246,0.525650183,0.884705447,0.615554937,1.281285513,0.683589703,DB0053710038435_,0.380397391,-0.122500517,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,ciprofloxacin,DB00537
,70965,DB01190,10038435,31,4903,34,2251,0.000667645,0.418649717,0.248131484,0.703938849,0.003940504,DB0119010038435_,5.536446563,-0.870720706,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,clindamycin,DB01190
,71016,DB00316,10041101,125,65349,86,36867,0.172596636,0.820005964,0.61794478,1.092390591,0.314274018,DB0031610041101_,1.157490005,-0.198443665,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,71017,DB00327,10041101,38,6100,18,4244,0.219898656,1.468726331,0.816612528,2.737833019,0.373302946,DB0032710041101_,0.985365001,0.384395584,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,hydromorphone,DB00327
,71018,DB00531,10041101,31,7221,29,6487,0.897513318,0.960295629,0.559182048,1.653517481,0.956338178,DB0053110041101_,0.044643686,-0.040514095,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,71022,DB00635,10041101,66,32987,61,23733,0.176675243,0.778448693,0.54097703,1.121705398,0.319597313,DB0063510041101_,1.140693473,-0.250452195,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,71024,DB00695,10041101,42,28007,38,20490,0.365697952,0.808622423,0.508678357,1.289185189,0.535299364,DB0069510041101_,0.62492913,-0.212423191,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,71027,DB01075,10041101,49,19899,28,11069,0.905692691,0.973436062,0.599428998,1.609556985,0.957861963,DB0107510041101_,0.0430516,-0.026923135,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,71036,DB00575,10046571,115,5129,28,3801,1.01572155856134e-08,3.043334751,1.994431149,4.790103909,2.28385296550768e-07,DB0057510046571_,15.29223174,1.112953872,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,clonidine,DB00575
,71038,DB00688,10046571,127,6363,43,5335,8.87440598288331e-08,2.476070547,1.735866126,3.592835019,1.62270442615713e-06,DB0068810046571_,13.3314164,0.906672847,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,71039,DB01115,10046571,68,3532,20,2248,0.001867511,2.163725737,1.294006052,3.772922805,0.009200174,DB0111510046571_,4.688532888,0.771831614,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,nifedipine,DB01115
,71040,DB01306,10046571,120,4088,46,3820,1.020237308337e-07,2.437256161,1.716089419,3.513349813,1.8449905503707e-06,DB0130610046571_,13.2030364,0.890872882,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,insulin aspart,DB01306
,71041,DB01610,10046571,38,903,16,1202,7.28144320832449e-05,3.159761509,1.70764805,6.109189871,0.000606922,DB0161010046571_,7.407110892,1.150496553,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,valganciclovir,DB01610
,71045,DB00316,10047626,69,65405,26,36927,0.086984587,1.498328707,0.941761913,2.451838192,0.190017858,DB0031610047626_,1.66063722,0.404350291,NA,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,71051,DB00635,10047626,38,33015,17,23777,0.102949991,1.609815263,0.886651473,3.042439971,0.215397637,DB0063510047626_,1.535269485,0.476119429,NA,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,71053,DB00695,10047626,34,28015,18,20510,0.325633993,1.382860046,0.75913038,2.601617166,0.494113986,DB0069510047626_,0.704989048,0.324153851,NA,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,71067,DB00316,10059895,45,65429,32,36921,0.342627459,0.793550643,0.493187228,1.290457951,0.511943097,DB0031610059895_,0.669541799,-0.231237918,NA,10059895,Urine output decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,71074,DB00695,10059895,35,28014,47,20481,0.006971758,0.544453861,0.34101508,0.861894316,0.026703671,DB0069510059895_,3.622954226,-0.607972077,NA,10059895,Urine output decreased,10022891,Investigations,Inv,furosemide,DB00695
,71087,DB00575,10061428,83,5161,54,3775,0.542316119,1.124209514,0.786383063,1.618747768,0.697549813,DB0057510061428_,0.360181352,0.117080134,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,clonidine,DB00575
,71089,DB01115,10061428,88,3512,39,2229,0.065697147,1.432016699,0.967611771,2.153284174,0.153637195,DB0111510061428_,1.873161335,0.359083729,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,nifedipine,DB01115
,71090,DB01190,10061428,55,4879,42,2243,0.015443489,0.602061474,0.394282216,0.925249957,0.050438881,DB0119010061428_,2.986992952,-0.507395723,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,clindamycin,DB01190
,71120,DB08907,10020993,39,4214,38,3872,0.819496339,0.943001491,0.586225475,1.518172434,0.903789257,DB0890710020993_,0.101159068,-0.058687416,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,canagliflozin,DB08907
,71124,DB00051,10050551,121,25610,25,11395,0.000211175,2.153488141,1.39033453,3.460397914,0.001508148,DB0005110050551_,6.496872972,0.767088919,NA,10050551,Lupus-like syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,71137,DB00811,10073071,6,2792,81,4075,1.90578495235303e-12,0.108121902,0.038476589,0.246251339,8.18522180924827e-11,DB0081110073071_,23.22610571,-2.224495967,male,10073071,Hepatocellular carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ribavirin,DB00811
,71138,DB08934,10073071,9,4480,86,6118,2.98655180350465e-12,0.142950419,0.063171692,0.284615057,1.24309602779287e-10,DB0893410073071_,22.80824587,-1.94525743,male,10073071,Hepatocellular carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sofosbuvir,DB08934
,71142,DB01018,10041349,19,393,47,732,0.352446874,0.753136052,0.411384075,1.329523868,0.522178752,DB0101810041349_,0.649745314,-0.283509387,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,guanfacine,DB01018
,71161,DB00641,10000059,178,13946,119,12356,0.01923336,1.325244123,1.043491422,1.688030942,0.059955987,DB0064110000059_,2.81414454,0.281596686,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,71163,DB14513,10000059,108,7069,29,3535,0.002459411,1.862236236,1.223518713,2.917211248,0.011518149,DB1451310000059_,4.463831346,0.621778043,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,71165,DB14500,10012174,143,7666,72,4001,0.828207306,1.036579536,0.773420311,1.399566779,0.909674858,DB1450010012174_,0.094668042,0.035926385,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,potassium,DB14500
,71166,DB00115,10013911,124,18301,63,10409,0.492847462,1.11948958,0.8193086,1.542778763,0.655706183,DB0011510013911_,0.422042483,0.112872849,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,71168,DB14513,10013911,47,7130,25,3539,0.802125329,0.933151757,0.561736791,1.584869735,0.892948956,DB1451310013911_,0.11322586,-0.069187436,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,71176,DB00115,10042128,152,18273,46,10426,0.00010432,1.885317913,1.346227295,2.684942549,0.000827415,DB0011510042128_,7.097204478,0.634096461,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,71177,DB00331,10042128,108,24838,54,20698,0.001988058,1.666617466,1.190765481,2.356605133,0.009677955,DB0033110042128_,4.637904708,0.510796103,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,71178,DB00338,10042128,226,33448,98,22174,0.000402329,1.528807253,1.200165488,1.9593387,0.002575551,DB0033810042128_,5.961691623,0.424487858,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,71179,DB00641,10042128,71,14053,40,12435,0.022186172,1.570603194,1.050615406,2.377267913,0.067049558,DB0064110042128_,2.702323267,0.451459746,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,71181,DB14513,10042128,51,7126,14,3550,0.0475779,1.814692886,0.987729102,3.554990797,0.120526705,DB1451310042128_,2.115883931,0.595916245,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,71183,DB14513,10047895,177,7000,70,3494,0.115665183,1.262043537,0.948743033,1.694427324,0.234669393,DB1451310047895_,1.449577593,0.232732262,NA,10047895,Weight decreased,10022891,Investigations,Inv,magnesium,DB14513
,71195,DB06403,10028596,71,21400,35,6626,0.029088749,0.628110794,0.412973655,0.971312314,0.082701535,DB0640310028596_,2.492517116,-0.465038705,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,ambrisentan,DB06403
,71196,DB09072,10013709,185,6286,67,2468,0.619217039,1.084085266,0.812131094,1.461770077,0.760033615,DB0907210013709_,0.274392616,0.080736559,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,71205,DB00051,10009900,108,25623,118,11302,2.03884526002725e-11,0.403716529,0.307764133,0.52913576,7.3969700013549e-10,DB0005110009900_,21.02478047,-0.907042307,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,71206,DB01222,10009900,30,9244,24,5381,0.259538702,0.727671955,0.410780438,1.301994896,0.42068734,DB0122210009900_,0.865865381,-0.317904943,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,71207,DB00230,10036495,168,19506,69,8582,0.671209705,1.071221034,0.803778166,1.440874893,0.80052394,DB0023010036495_,0.222488841,0.068799151,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,71208,DB00338,10036495,49,33625,18,22254,0.033354626,1.801623783,1.030668047,3.287020406,0.09205828,DB0033810036495_,2.385333429,0.58868836,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,71209,DB00451,10036495,68,47203,15,15404,0.201749772,1.479345976,0.836767412,2.787553224,0.351145065,DB0045110036495_,1.046555852,0.391600082,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,71220,DB01240,10037087,166,5585,32,1544,0.065604747,1.434026695,0.972986147,2.173821561,0.153494218,DB0124010037087_,1.87409238,0.360486358,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,epoprostenol,DB01240
,71221,DB00820,10040829,34,11881,16,5800,1,1.03735066,0.556658592,2.014512386,1,DB0082010040829_,0,0.036670021,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,tadalafil,DB00820
,71224,DB06210,10016256,72,1388,43,1018,0.333879855,1.227968755,0.822399228,1.852319615,0.502924469,DB0621010016256_,0.687315282,0.205361385,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,eltrombopag,DB06210
,71227,DB00060,10012374,51,9457,14,2451,0.877649621,0.944128046,0.513716494,1.850206325,0.948114907,DB0006010012374_,0.053279574,-0.05749348,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,interferon beta-1a,DB00060
,71232,DB14500,10003239,192,7617,58,4015,0.000152316,1.744842348,1.291050526,2.38902664,0.001142258,DB1450010003239_,6.774748151,0.556664206,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,71233,DB00169,10013082,103,38588,36,18139,0.144792238,1.344956254,0.911672502,2.025072593,0.276737024,DB0016910013082_,1.284687597,0.296361488,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,71235,DB00586,10020937,122,6987,28,2777,0.007883847,1.731676716,1.137749839,2.719698716,0.029433553,DB0058610020937_,3.525619999,0.549090139,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,71236,DB00586,10033775,91,7018,30,2775,0.418200366,1.199384747,0.784053593,1.882155212,0.587200674,DB0058610033775_,0.532388653,0.181808714,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,71239,DB00381,10003553,141,29219,43,22844,9.65680627356324e-09,2.563549984,1.809573817,3.697878956,2.18066282560661e-07,DB0038110003553_,15.33846677,0.94139301,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,71241,DB00316,10003986,77,65397,41,36912,0.847973368,1.060030313,0.716408966,1.588873362,0.923978827,DB0031610003986_,0.079066122,0.058297505,NA,10003986,Back injury,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,71245,DB00316,10012267,73,65401,52,36901,0.225485161,0.792104246,0.547331423,1.153446657,0.380265198,DB0031610012267_,0.966886381,-0.233062272,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,71247,DB00381,10012267,43,29317,35,22852,0.909202866,0.957624297,0.598453101,1.541905726,0.959182187,DB0038110012267_,0.041674246,-0.043299753,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,71254,DB00370,10027175,54,4487,23,3640,0.010816276,1.904468946,1.146653826,3.257936706,0.037907443,DB0037010027175_,3.272607806,0.644203201,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,mirtazapine,DB00370
,71255,DB00575,10027175,51,5193,18,3811,0.006789429,2.07913449,1.19199272,3.787949255,0.026159503,DB0057510027175_,3.643542738,0.731951696,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,71258,DB00588,10049438,44,16480,21,8447,0.895756722,1.073932081,0.624596703,1.902706884,0.956179558,DB0058810049438_,0.044809561,0.071326755,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,71259,DB01068,10049438,40,13723,23,6817,0.593049944,0.863940064,0.504407402,1.512930468,0.739220761,DB0106810049438_,0.302158674,-0.146251883,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,71270,DB00316,10060933,170,65304,94,36859,0.898041273,1.02076322,0.788563625,1.328059008,0.956338178,DB0031610060933_,0.044643686,0.020550602,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,71272,DB01068,10060933,44,13719,26,6814,0.525199146,0.840560383,0.505754821,1.423267094,0.683324319,DB0106810060933_,0.380785687,-0.173686487,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,71273,DB00321,10010774,122,7325,43,2807,0.725712058,1.087232177,0.759895174,1.581692042,0.839343561,DB0032110010774_,0.175135168,0.08363518,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,amitriptyline,DB00321
,71274,DB01591,10010774,55,1900,27,629,0.119480589,0.674477442,0.414110102,1.1223745,0.240549426,DB0159110010774_,1.424829697,-0.393817048,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,solifenacin,DB01591
,71289,DB00190,10016173,277,3020,452,4222,0.053316707,0.856767097,0.729705395,1.004615104,0.13121386,DB0019010016173_,2.030926765,-0.154589163,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,carbidopa,DB00190
,71297,DB00108,10063400,34,10160,16,3279,0.246936333,0.685835702,0.367810098,1.332456135,0.406063468,DB0010810063400_,0.901245805,-0.377117182,NA,10063400,Secondary progressive multiple sclerosis,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,71304,DB00158,10051792,94,16721,39,8065,0.458980255,1.162515164,0.791523895,1.736595083,0.626358757,DB0015810051792_,0.467831978,0.150585903,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,71306,DB01373,10051792,57,22663,20,7361,0.790851214,0.925681597,0.547267731,1.627895472,0.886688456,DB0137310051792_,0.120261592,-0.077224952,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,71307,DB05679,10051792,56,6875,31,4878,0.277268814,1.28169978,0.810879435,2.060022552,0.44081599,DB0567910051792_,0.819127746,0.24818715,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,ustekinumab,DB05679
,71311,DB00203,10016766,72,13806,42,8896,0.631969628,1.104627497,0.744016591,1.658526055,0.770701819,DB0020310016766_,0.260453725,0.099508171,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,71313,DB00863,10016766,44,10629,28,5812,0.538351329,0.859281161,0.522487323,1.434908072,0.694284753,DB0086310016766_,0.364873096,-0.151659098,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,71315,DB00203,10038063,60,13818,17,8921,0.002146512,2.27853156,1.310977035,4.168273487,0.010310866,DB0020310038063_,4.574557005,0.823531183,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,71324,DB00927,10000087,127,7370,35,4981,6.47565827506192e-07,2.452190947,1.671959781,3.68125578,9.74035351988569e-06,DB0092710000087_,11.53923315,0.896981889,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,71327,DB08906,10011224,88,2105,31,1127,0.049634969,1.519644684,0.991633666,2.38393736,0.124329838,DB0890610011224_,2.084817262,0.418476547,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone furoate,DB08906
,71328,DB08906,10013968,174,2019,95,1063,0.789411059,0.964360405,0.738105428,1.265834533,0.885855574,DB0890610013968_,0.12120135,-0.036290191,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone furoate,DB08906
,71329,DB08906,10016256,156,2037,58,1100,0.017464874,1.452286901,1.057529704,2.016987949,0.055559967,DB0890610016256_,2.890292359,0.373139487,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fluticasone furoate,DB08906
,71336,DB00158,10028735,108,16707,28,8076,0.002381904,1.864463469,1.219707913,2.938101905,0.011220133,DB0015810028735_,4.490045529,0.622973328,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,71337,DB00186,10028735,80,16821,19,9989,0.000148583,2.500304344,1.500671543,4.370504391,0.001116827,DB0018610028735_,6.797263391,0.916412462,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,71338,DB00316,10028735,316,65158,110,36843,7.96030872717138e-06,1.624349668,1.303031677,2.03761668,8.90937683175218e-05,DB0031610028735_,9.325821166,0.485107531,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,71339,DB00904,10028735,125,22944,50,14406,0.006372362,1.569672508,1.121424496,2.226388269,0.024846298,DB0090410028735_,3.695046502,0.450867004,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,71340,DB00927,10028735,60,7437,22,4994,0.017040815,1.831296681,1.105302561,3.139863334,0.054494534,DB0092710028735_,2.909654877,0.605024285,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,71344,DB00158,10047571,119,16696,38,8066,0.026144518,1.512872922,1.040938827,2.243614897,0.076056516,DB0015810047571_,2.576278585,0.414010441,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,folic acid,DB00158
,71345,DB00927,10047571,54,7443,11,5005,0.000104179,3.300802893,1.704330558,7.006717733,0.000826541,DB0092710047571_,7.098260458,1.19416574,female,10047571,Visual impairment,10015919,Eye disorders,Eye,famotidine,DB00927
,71347,DB00158,10047924,61,16754,17,8087,0.051908862,1.731973301,0.997782639,3.165422099,0.128628277,DB0015810047924_,2.05082861,0.549261395,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,71348,DB00186,10047924,56,16845,20,9988,0.05672026,1.660189539,0.98014232,2.922807993,0.137314487,DB0018610047924_,1.98548146,0.506931776,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,71349,DB00904,10047924,86,22983,47,14409,0.476211325,1.147196954,0.794339614,1.674759819,0.641621308,DB0090410047924_,0.443757012,0.137321536,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,71350,DB00927,10047924,43,7454,18,4998,0.115302522,1.601720898,0.903329565,2.954166582,0.234105268,DB0092710047924_,1.451984401,0.471078612,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,71364,DB00331,10039073,108,24838,30,20722,8.70374011973185e-09,3.003242029,1.987434683,4.665919571,1.98419608887382e-07,DB0033110039073_,15.43288181,1.099692382,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,71366,DB00331,10046306,156,24790,46,20706,3.2590473747198e-11,2.832450223,2.025848099,4.028385428,1.15062538944943e-09,DB0033110046306_,20.58296023,1.04114214,female,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,metformin,DB00331
,71367,DB00563,10046306,427,46219,89,15259,4.93050111853522e-05,1.583893462,1.256852177,2.014998116,0.000436431,DB0056310046306_,7.73687999,0.459886032,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,71369,DB00316,10007617,699,64775,448,36505,0.035522019,0.879319485,0.779263396,0.99298382,0.096540999,DB0031610007617_,2.337787501,-0.128606983,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,71370,DB00761,10007617,33,15274,38,8587,0.002796168,0.488228598,0.296534889,0.800183496,0.012759324,DB0076110007617_,4.361492997,-0.716971544,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,71372,DB00112,10015090,110,5823,66,4025,0.395105081,1.151990615,0.839045794,1.592186387,0.564952771,DB0011210015090_,0.571013143,0.141491416,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bevacizumab,DB00112
,71373,DB00331,10015090,103,24843,79,20673,0.602329134,1.084976031,0.800942949,1.474409007,0.746347516,DB0033110015090_,0.292563949,0.081557895,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,71377,DB00421,10005483,73,8830,79,5173,0.000187703,0.541398208,0.387603609,0.755283318,0.001367074,DB0042110005483_,6.595082818,-0.613600212,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,spironolactone,DB00421
,71396,DB00019,10046735,43,18969,11,9518,0.043403456,1.961407759,0.994086738,4.219552123,0.112446294,DB0001910046735_,2.185279562,0.67366246,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,pegfilgrastim,DB00019
,71400,DB00836,10008479,94,5441,43,4032,0.008859918,1.619868627,1.114919805,2.386874241,0.032311194,DB0083610008479_,3.432341539,0.482345051,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,71408,DB00327,10035664,179,5959,145,4117,0.168513266,0.852905809,0.678775946,1.073167642,0.308967723,DB0032710035664_,1.174518462,-0.15910616,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,hydromorphone,DB00327
,71412,DB09570,10035226,155,3746,186,3749,0.108322364,0.834021293,0.666223884,1.042980939,0.223533136,DB0957010035226_,1.498195615,-0.181496346,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ixazomib,DB09570
,71423,DB00471,10013952,105,14084,29,5436,0.121612238,1.397410745,0.917595449,2.190058805,0.243731662,DB0047110013952_,1.411687407,0.334621057,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,71425,DB14512,10013952,42,4802,8,2404,0.009695837,2.627990748,1.216359743,6.490962309,0.034726131,DB1451210013952_,3.360262824,0.96621958,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mometasone furoate,DB14512
,71434,DB00227,10003239,78,2389,23,1780,5.66858216634319e-05,2.526269391,1.562278981,4.233346245,0.000491583,DB0022710003239_,7.617880601,0.926743665,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lovastatin,DB00227
,71435,DB01409,10003239,136,5895,48,3918,0.00013025,1.883005389,1.342086747,2.68134715,0.000998867,DB0140910003239_,6.908889275,0.632869112,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tiotropium,DB01409
,71436,DB00177,10013946,34,4766,17,2833,0.663389992,1.188850885,0.64456381,2.273557094,0.794876507,DB0017710013946_,0.229568513,0.172987198,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,valsartan,DB00177
,71438,DB01409,10013946,40,5991,18,3948,0.225359397,1.46436478,0.819010403,2.71778335,0.380203578,DB0140910013946_,0.967048437,0.381421551,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,tiotropium,DB01409
,71439,DB00227,10013968,105,2362,69,1734,0.530892117,1.117078863,0.811195427,1.546482997,0.687850894,DB0022710013968_,0.374183189,0.11071712,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lovastatin,DB00227
,71440,DB00177,10020937,56,4744,30,2820,0.736728017,1.109614041,0.698053525,1.795658846,0.84807287,DB0017710020937_,0.164788715,0.104012244,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,valsartan,DB00177
,71441,DB00227,10020937,42,2425,15,1788,0.014834292,2.064155549,1.11730998,4.02036983,0.048880453,DB0022710020937_,3.018377694,0.724721208,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,lovastatin,DB00227
,71442,DB00381,10020937,334,29026,178,22709,3.03895860053804e-05,1.468025021,1.219216465,1.772412422,0.000287076,DB0038110020937_,8.155761944,0.383917974,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,71443,DB00863,10020937,152,10521,47,5793,0.000427213,1.780648557,1.273939641,2.529418861,0.002707487,DB0086310020937_,5.911734538,0.576977656,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,71444,DB00227,10033425,67,2400,33,1770,0.065050441,1.497210371,0.967968424,2.356440772,0.152522265,DB0022710033425_,1.880444692,0.403603624,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,lovastatin,DB00227
,71453,DB00381,10047924,120,29240,49,22838,9.29993418879351e-05,1.912743582,1.360530234,2.725505765,0.000749728,DB0038110047924_,7.195800265,0.648538642,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,71469,DB00319,10040047,60,1332,82,1771,0.930971087,0.9728685,0.680030694,1.385151202,0.972103284,DB0031910040047_,0.028293221,-0.027506355,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,piperacillin,DB00319
,71470,DB00425,10040047,134,12561,96,7388,0.149484074,0.821004519,0.625989777,1.080169956,0.28324256,DB0042510040047_,1.261451647,-0.197226665,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,zolpidem,DB00425
,71471,DB00441,10040047,61,2213,72,1822,0.042082809,0.697600646,0.484809695,1.001015248,0.109867565,DB0044110040047_,2.208479598,-0.36010848,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,gemcitabine,DB00441
,71475,DB01065,10040047,48,4283,54,2997,0.019553427,0.622050424,0.411475689,0.937907286,0.060725448,DB0106510040047_,2.801392422,-0.474734122,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,melatonin,DB01065
,71477,DB01212,10040047,51,1968,53,1888,0.692394551,0.923183964,0.612600935,1.390038231,0.8146821,DB0121210040047_,0.204957303,-0.079926753,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ceftriaxone,DB01212
,71478,DB01225,10040047,102,4942,123,4517,0.042783212,0.757978613,0.575352946,0.996837055,0.111278746,DB0122510040047_,2.195716997,-0.277100109,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,enoxaparin,DB01225
,71479,DB01229,10040047,111,5630,101,2608,2.1511035746024e-06,0.509123842,0.383703784,0.676212399,2.8263812776018e-05,DB0122910040047_,10.47392827,-0.675063988,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,paclitaxel,DB01229
,71480,DB09104,10040047,21,1029,33,839,0.025661321,0.519046634,0.283093421,0.932142844,0.074961971,DB0910410040047_,2.590774344,-0.655761545,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,magnesium hydroxide,DB09104
,71481,DB13867,10040047,53,4497,28,2526,0.90736645,1.063228844,0.658574221,1.750561493,0.958745315,DB1386710040047_,0.042129813,0.061310358,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,fluticasone,DB13867
,71506,DB00230,10008190,232,19442,98,8553,0.764028168,1.041433643,0.817742626,1.334582869,0.869551495,DB0023010008190_,0.139777724,0.040598267,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,71507,DB01261,10008190,35,3746,38,3265,0.409299644,0.802814036,0.491171309,1.308769488,0.578689712,DB0126110008190_,0.546988848,-0.219632178,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,sitagliptin,DB01261
,71522,DB00736,10033645,46,10545,22,5531,0.798656224,1.096701283,0.645716779,1.916398892,0.891257487,DB0073610033645_,0.115121907,0.092306841,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,71527,DB01240,10038435,90,5661,38,1538,0.029379028,0.643504698,0.433820646,0.970854251,0.083326435,DB0124010038435_,2.484989427,-0.440825952,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,epoprostenol,DB01240
,71530,DB00213,10022061,82,18813,16,13405,1.45740338516725e-07,3.651609635,2.118737547,6.689855878,2.5564129448863e-06,DB0021310022061_,12.87690548,1.295168066,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,71532,DB00213,10022093,51,18844,9,13412,1.66941095576113e-05,4.03301835,1.965634538,9.321257326,0.000170277,DB0021310022093_,8.678082119,1.394515066,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,71533,DB00586,10022093,53,7056,6,2799,0.00121122,3.503979869,1.50502296,9.98771189,0.00645086,DB0058610022093_,5.043541769,1.253899428,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,71538,DB00635,10022107,86,32967,14,23780,2.54505969214747e-09,4.430894486,2.502063099,8.445803606,6.51698918734498e-08,DB0063510022107_,16.54626826,1.488601479,female,10022107,Injection site urticaria,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,71544,DB00213,10053425,54,18841,6,13415,1.08911148424503e-07,6.407244543,2.759152108,18.23090597,1.95943157860236e-06,DB0021310053425_,13.14285614,1.85742931,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,71545,DB00586,10053425,58,7051,6,2799,0.000393882,3.837208546,1.65743456,10.89513876,0.00253049,DB0058610053425_,5.979342311,1.344745161,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,71549,DB00331,10028411,251,24695,163,20589,0.013170637,1.283835784,1.048975268,1.574815669,0.044347197,DB0033110028411_,3.11570577,0.249852303,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,71550,DB00331,10057880,56,24890,46,20706,1,1.012748749,0.673080368,1.530523869,1,DB0033110057880_,0,0.012668168,NA,10057880,Injection site nodule,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,71556,DB00051,10062352,48,25683,10,11410,0.031491947,2.13242416,1.064791294,4.729292944,0.087999345,DB0005110062352_,2.43042591,0.757259436,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,adalimumab,DB00051
,71557,DB00588,10062352,77,16447,35,8433,0.617272593,1.128010769,0.746488944,1.735204803,0.758352821,DB0058810062352_,0.276606538,0.1204557,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,71562,DB00404,10001949,111,19781,56,9806,0.934355501,0.982595015,0.70569838,1.381570044,0.97479745,DB0040410001949_,0.025525574,-0.017558233,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,71563,DB00472,10001949,41,10718,16,4296,1,1.027119064,0.563319737,1.962922373,1,DB0047210001949_,0,0.026757858,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,71565,DB00381,10015958,71,29289,30,22857,0.004715987,1.846900703,1.189103613,2.933351512,0.019515067,DB0038110015958_,3.936568425,0.613508938,NA,10015958,Eye pain,10015919,Eye disorders,Eye,amlodipine,DB00381
,71567,DB00722,10015958,52,25351,43,25989,0.306154185,1.239728578,0.811416066,1.902863189,0.473104016,DB0072210015958_,0.748440009,0.214892467,NA,10015958,Eye pain,10015919,Eye disorders,Eye,lisinopril,DB00722
,71571,DB00316,10028245,157,65317,48,36905,0.000107735,1.848053966,1.329459227,2.610564101,0.000850136,DB0031610028245_,7.070114512,0.614133175,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,71572,DB00404,10028245,58,19834,17,9845,0.064619638,1.693469774,0.971859683,3.103961013,0.151782957,DB0040410028245_,1.885303694,0.526779545,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,71573,DB00381,10041466,69,29291,45,22842,0.395278301,1.195734744,0.809264566,1.782278106,0.564978732,DB0038110041466_,0.570967192,0.178760845,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,71574,DB00425,10041466,37,12658,24,7460,0.790836372,0.908588309,0.528789068,1.588901881,0.886688456,DB0042510041466_,0.120261592,-0.095863192,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,71575,DB00425,10047513,115,12580,29,7455,1.26077890606418e-05,2.349902946,1.550704903,3.667809947,0.000133091,DB0042510047513_,8.924480032,0.854374028,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,zolpidem,DB00425
,71576,DB00169,10049848,391,38300,177,17998,0.717588329,1.038056183,0.866182278,1.248007297,0.833158787,DB0016910049848_,0.182531035,0.037349909,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,71577,DB00404,10049848,143,19749,64,9798,0.553425541,1.108524438,0.819078021,1.514361959,0.707011279,DB0040410049848_,0.346708661,0.103029795,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,71578,DB00425,10049848,106,12589,50,7434,0.212090945,1.251904494,0.885117025,1.791541917,0.363879148,DB0042510049848_,1.010933479,0.224665987,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,71579,DB00722,10049848,167,25236,145,25887,0.155587218,1.18142924,0.939412041,1.487168344,0.291563114,DB0072210049848_,1.232498781,0.166724926,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,71584,DB00108,10073085,194,10000,57,3238,0.553680171,1.102047529,0.814004743,1.511983663,0.707235071,DB0010810073085_,0.346392177,0.09716984,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,natalizumab,DB00108
,71586,DB01307,10000087,32,2492,20,2049,0.400823702,1.315490958,0.727100784,2.434841486,0.570682285,DB0130710000087_,0.560922643,0.274209948,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,insulin detemir,DB01307
,71587,DB06655,10000087,72,3616,37,2082,0.61652297,1.120422603,0.740657504,1.720196081,0.757634803,DB0665510000087_,0.277553799,0.113705938,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,liraglutide,DB06655
,71588,DB00115,10001551,63,18362,24,10448,0.09507133,1.493608311,0.91940885,2.501328096,0.203337412,DB0011510001551_,1.592888551,0.401194877,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,71592,DB00115,10003481,61,18364,24,10448,0.141819464,1.446036187,0.887740802,2.426714122,0.272285498,DB0011510003481_,1.300904138,0.368826149,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,71597,DB00331,10005364,42,24904,35,20717,1,0.998249278,0.621947049,1.61118117,1,DB0033110005364_,0,-0.001752256,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,metformin,DB00331
,71599,DB00999,10005364,34,21396,16,12223,0.559813291,1.213912373,0.651718085,2.356290445,0.712472395,DB0099910005364_,0.339014112,0.19384851,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,71602,DB00115,10008629,41,18384,20,10452,0.689404067,1.165476325,0.666949176,2.101028347,0.812764276,DB0011510008629_,0.207314155,0.153129866,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,cyanocobalamin,DB00115
,71605,DB06655,10008629,48,3640,21,2098,0.316641803,1.317365321,0.77130766,2.323098612,0.484398195,DB0665510008629_,0.724847993,0.275633773,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,liraglutide,DB06655
,71606,DB00331,10008796,36,24910,42,20710,0.140208764,0.712634411,0.443423423,1.139941662,0.270140176,DB0033110008796_,1.308814283,-0.338786738,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,71613,DB00331,10059570,40,24906,14,20738,0.00387616,2.378897792,1.266681995,4.735314978,0.016627476,DB0033110059570_,4.096698745,0.866637268,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,metformin,DB00331
,71629,DB00537,10040070,36,7521,33,4265,0.058681606,0.618627751,0.374322745,1.025493071,0.141030084,DB0053710040070_,1.958782051,-0.480251559,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,71632,DB00186,10035742,58,16843,46,9962,0.154453559,0.745783601,0.497312678,1.124080447,0.290064134,DB0018610035742_,1.237653228,-0.293319801,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,71634,DB00451,10035742,74,47197,40,15379,0.011994562,0.602822702,0.404761785,0.909567075,0.041132038,DB0045110035742_,3.190967941,-0.506132152,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,71638,DB00761,10035742,35,15272,26,8599,0.287837271,0.757989579,0.44308101,1.312189955,0.452838706,DB0076110035742_,0.792219275,-0.277085641,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,71639,DB00999,10035742,32,21398,29,12210,0.082595986,0.629682542,0.368757473,1.079363116,0.182708646,DB0099910035742_,1.699862492,-0.462539488,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,71640,DB01050,10035742,31,18077,20,9351,0.461135033,0.801819041,0.442390819,1.485146318,0.628450995,DB0105010035742_,0.464497226,-0.220872331,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,71641,DB06186,10035742,56,2153,118,3528,0.131871766,0.777702611,0.552806596,1.08301853,0.258443883,DB0618610035742_,1.353076695,-0.251411076,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipilimumab,DB06186
,71642,DB09035,10035742,165,4561,259,6431,0.314970823,0.898242726,0.731652798,1.100392761,0.482529978,DB0903510035742_,0.72871223,-0.107314951,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nivolumab,DB09035
,71644,DB00997,10001760,64,5267,10,3504,1.02764033170143e-06,4.257204267,2.167493475,9.314976219,1.46431995091599e-05,DB0099710001760_,11.13153453,1.448612669,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,doxorubicin,DB00997
,71651,DB00381,10027599,126,29234,29,22858,5.66886081737633e-11,3.39707126,2.253423257,5.279820735,1.92813629071121e-09,DB0038110027599_,20.06671195,1.222913666,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,71659,DB08896,10031009,34,789,25,1015,0.044861952,1.748993776,1.003883469,3.085610692,0.115324833,DB0889610031009_,2.160002497,0.559040637,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,regorafenib,DB08896
,71663,DB06228,10019303,86,15826,40,16036,3.34546531643208e-05,2.178466868,1.479455527,3.256751439,0.000312327,DB0622810019303_,8.071461104,0.778621358,NA,10019303,Heart rate increased,10022891,Investigations,Inv,rivaroxaban,DB06228
,71664,DB00196,10021789,88,4995,38,3247,0.034795854,1.505308169,1.015058853,2.270316464,0.09503612,DB0019610021789_,2.353498247,0.408997641,NA,10021789,Infection,10021881,Infections and infestations,Infec,fluconazole,DB00196
,71665,DB06228,10021789,74,15838,54,16022,0.076234155,1.386270812,0.962287998,2.008254807,0.171846385,DB0622810021789_,1.76115431,0.326617273,NA,10021789,Infection,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,71667,DB08917,10008479,40,876,11,183,0.449482771,0.75985537,0.373840505,1.674015744,0.617086483,DB0891710008479_,0.482746098,-0.274627166,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ferric carboxymaltose,DB08917
,71707,DB00264,10018985,51,29556,77,24815,0.001293912,0.556106966,0.382343821,0.802833962,0.006800738,DB0026410018985_,4.990724196,-0.586794618,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,71712,DB00635,10018985,33,33020,50,23744,0.00078612,0.474593076,0.296120172,0.751627472,0.00450816,DB0063510018985_,5.401866191,-0.745297524,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,71724,DB00230,10007554,30,19644,22,8629,0.071094342,0.599015016,0.333931619,1.090501123,0.163213658,DB0023010007554_,1.812695152,-0.512468612,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,pregabalin,DB00230
,71729,DB00559,10013709,69,9590,32,3274,0.168505273,0.73615669,0.476489134,1.159525414,0.308964536,DB0055910013709_,1.174528778,-0.306312289,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,71738,DB00868,10011906,141,2843,121,1525,0.000316576,0.625108465,0.48280695,0.810361481,0.0021085,DB0086810011906_,6.161778713,-0.469830101,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,benzonatate,DB00868
,71739,DB01225,10011906,240,4804,253,4387,0.126778032,0.866288148,0.719479023,1.042849682,0.251148251,DB0122510011906_,1.381711871,-0.143537691,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,71759,DB01409,10024855,44,5987,26,3940,0.714154562,1.113707199,0.669498332,1.887333742,0.830507805,DB0140910024855_,0.185717952,0.107694269,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,tiotropium,DB01409
,71760,DB00186,10028372,164,16737,85,9923,0.324069945,1.143926229,0.87391965,1.506329572,0.492498399,DB0018610028372_,0.708264069,0.134466406,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,71762,DB00186,10037400,53,16848,30,9978,0.909672578,1.046286066,0.65594502,1.697407812,0.959437782,DB0018610037400_,0.04140781,0.045246814,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,71763,DB00295,10037400,48,14615,29,9573,0.815676289,1.084167983,0.669376572,1.784354652,0.901202213,DB0029510037400_,0.104025614,0.080812857,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,71776,DB00316,10017553,38,65436,17,36936,0.483997519,1.261764348,0.695014103,2.384285134,0.648215366,DB0031610017553_,0.433532283,0.232511017,NA,10017553,Furuncle,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,71786,DB01076,10000060,152,25595,117,25466,0.037733728,1.292587606,1.008367233,1.660403131,0.101077785,DB0107610000060_,2.291864912,0.256646105,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,71787,DB05351,10000060,41,2682,10,1121,0.162460374,1.7134719,0.840378861,3.849832084,0.300607193,DB0535110000060_,1.201950873,0.538521663,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,dexlansoprazole,DB05351
,71793,DB05351,10012735,167,2556,46,1085,0.010502904,1.540929687,1.096461726,2.202089315,0.03701647,DB0535110012735_,3.296392328,0.432385927,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dexlansoprazole,DB05351
,71794,DB05351,10016256,162,2561,52,1079,0.104671968,1.312536425,0.946407143,1.845285709,0.218019943,DB0535110016256_,1.52316874,0.271961468,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dexlansoprazole,DB05351
,71798,DB01276,10005557,101,1916,73,1438,0.875196018,1.038387878,0.754569843,1.434636842,0.946235791,DB0127610005557_,0.05526349,0.037669393,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,exenatide,DB01276
,71802,DB00295,10007617,182,14481,119,9483,1,1.001547609,0.789369062,1.274648724,1,DB0029510007617_,0,0.001546413,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,morphine,DB00295
,71812,DB01042,10028813,30,960,33,1295,0.44057751,1.226209465,0.716935863,2.089878202,0.608931242,DB0104210028813_,0.496049921,0.203927675,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,melphalan,DB01042
,71829,DB00007,10022086,63,1884,76,4376,0.000179746,1.925277244,1.350116582,2.737277565,0.0013177,DB0000710022086_,6.631867446,0.65506998,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,leuprolide,DB00007
,71830,DB01068,10022086,140,13623,37,6803,0.000390295,1.8894788,1.305370765,2.796665985,0.002512283,DB0106810022086_,5.986563384,0.636301024,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,71831,DB01224,10022086,67,8041,29,5888,0.01706239,1.691677983,1.077461698,2.716971165,0.054541932,DB0122410022086_,2.90878547,0.525720926,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,71834,DB00316,10042604,52,65422,24,36929,0.474023697,1.222981287,0.740354512,2.074930928,0.63978996,DB0031610042604_,0.446615344,0.201291556,NA,10042604,Supraventricular tachycardia,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,71845,DB01015,10012174,125,9762,153,9228,0.034397138,0.772315529,0.603751738,0.98641219,0.094204614,DB0101510012174_,2.362286116,-0.258362096,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,sulfamethoxazole,DB01015
,71846,DB09270,10012174,42,3072,34,2334,0.816122774,0.938557335,0.580893534,1.526259053,0.901430281,DB0927010012174_,0.103772576,-0.063411333,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ubidecarenone,DB09270
,71849,DB11133,10012174,32,2399,18,1556,0.665061256,1.153071072,0.625475175,2.189861791,0.796135038,DB1113310012174_,0.227986461,0.14242888,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,omega-3 fatty acids,DB11133
,71879,DB00169,10063743,83,38608,42,18133,0.701414141,0.928159354,0.632668626,1.37990096,0.820684206,DB0016910063743_,0.197616889,-0.074551843,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,71900,DB00904,10006093,75,22994,58,14398,0.246004763,0.809707416,0.566704513,1.161907268,0.404974961,DB0090410006093_,0.903930038,-0.211082311,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,ondansetron,DB00904
,71916,DB00433,10028391,42,7614,15,6005,0.007173378,2.208148236,1.198347005,4.291064031,0.027307335,DB0043310028391_,3.600599921,0.792154262,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,prochlorperazine,DB00433
,71922,DB11089,10028391,61,10114,32,8375,0.03683935,1.578448275,1.011793339,2.505101919,0.099248944,DB1108910028391_,2.310124001,0.45644226,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,71926,DB01377,10033425,87,3709,38,2632,0.01308341,1.624549033,1.093723128,2.453400859,0.044117696,DB0137710033425_,3.120894311,0.485230259,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium oxide,DB01377
,71930,DB01222,10042458,38,9236,19,5386,0.680260904,1.166323976,0.655120074,2.144111505,0.80660187,DB0122210042458_,0.214925079,0.153856901,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,budesonide,DB01222
,71941,DB00682,10067482,30,19429,27,16337,0.792180177,0.934304413,0.53656527,1.634097337,0.88743507,DB0068210067482_,0.119419921,-0.067952969,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,71944,DB01041,10038435,35,3010,40,3078,0.644198401,0.894783919,0.550198799,1.449086654,0.780401197,DB0104110038435_,0.247947136,-0.111173021,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,thalidomide,DB01041
,71946,DB00047,10000059,91,9194,67,8451,0.174652493,1.248429946,0.899316388,1.740631465,0.316985381,DB0004710000059_,1.148899623,0.221886718,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,71947,DB00927,10000059,118,7379,41,4975,0.000166857,1.940309188,1.346816018,2.845458673,0.001236839,DB0092710000059_,6.695196334,0.662847336,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,71948,DB01069,10000059,89,6611,32,2363,1,0.994115508,0.654939239,1.543606901,1,DB0106910000059_,0,-0.005901874,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,promethazine,DB01069
,71949,DB01233,10000059,37,3384,19,1707,1,0.982309849,0.548709182,1.814129698,1,DB0123310000059_,0,-0.017848492,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,metoclopramide,DB01233
,71951,DB01069,10002034,131,6569,54,2341,0.398901591,0.86456123,0.622704285,1.214497448,0.568777473,DB0106910002034_,0.564266005,-0.145533149,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,promethazine,DB01069
,71952,DB01233,10002034,71,3350,32,1694,0.673443664,1.121927673,0.726025133,1.767880258,0.801932938,DB0123310002034_,0.220730293,0.115048342,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,metoclopramide,DB01233
,71961,DB00008,10029354,46,1479,57,1619,0.549238557,0.883443121,0.581776352,1.335288561,0.703578901,DB0000810029354_,0.351575254,-0.123928368,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,peginterferon alfa-2a,DB00008
,71962,DB00047,10029354,36,9249,58,8460,0.009292955,0.567763843,0.363414484,0.876300834,0.03355754,DB0004710029354_,3.394493716,-0.566049717,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,insulin glargine,DB00047
,71964,DB00331,10029354,109,24837,110,20642,0.153705988,0.823549586,0.625650368,1.083960503,0.289088897,DB0033110029354_,1.241021036,-0.194131517,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,metformin,DB00331
,71965,DB00927,10029354,99,7398,56,4960,0.323585875,1.185218163,0.843772905,1.67911375,0.492014504,DB0092710029354_,0.709247083,0.169926862,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,famotidine,DB00927
,71966,DB01069,10029354,42,6658,26,2369,0.036932398,0.574817136,0.34344973,0.978865873,0.099453752,DB0106910029354_,2.308062548,-0.553703313,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,promethazine,DB01069
,71967,DB01233,10029354,33,3388,26,1700,0.095890433,0.636905513,0.368112155,1.112826463,0.204609329,DB0123310029354_,1.586652829,-0.451133966,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,metoclopramide,DB01233
,71969,DB00047,10033661,17,9268,33,8485,0.010634081,0.471652212,0.246202577,0.872142163,0.037378552,DB0004710033661_,3.286658203,-0.751513403,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,insulin glargine,DB00047
,71974,DB00008,10037087,51,1474,59,1617,0.84610529,0.948267427,0.634391717,1.4133599,0.922644218,DB0000810037087_,0.080511582,-0.053118721,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,peginterferon alfa-2a,DB00008
,71975,DB00222,10037087,55,3151,41,3087,0.217005854,1.314156772,0.858328779,2.026236338,0.369897142,DB0022210037087_,0.994530307,0.273195222,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,glimepiride,DB00222
,71979,DB00047,10060795,29,9256,31,8487,0.605427942,0.857771253,0.498289565,1.472618104,0.748526504,DB0004710060795_,0.289648667,-0.15341782,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,insulin glargine,DB00047
,71993,DB00512,10043554,87,4650,141,4957,0.002482689,0.657788404,0.496080541,0.868097018,0.011602509,DB0051210043554_,4.45653393,-0.418871974,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,vancomycin,DB00512
,71994,DB01075,10043554,115,19833,127,10970,1.13782041431128e-07,0.500854343,0.385315108,0.650488339,2.04147505734962e-06,DB0107510043554_,13.10183794,-0.691439952,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,diphenhydramine,DB01075
,71995,DB01076,10043554,122,25625,157,25426,0.035447628,0.771041605,0.603160675,0.983734364,0.096383667,DB0107610043554_,2.339418517,-0.260012945,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,atorvastatin,DB01076
,71996,DB06228,10043554,83,15829,91,15985,0.595618638,0.921101454,0.675162734,1.255164742,0.74122358,DB0622810043554_,0.299452972,-0.082185092,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,rivaroxaban,DB06228
,72007,DB00404,10016322,446,19446,141,9721,1.29130542626438e-06,1.581212259,1.30338655,1.927770246,1.7968217643917e-05,DB0040410016322_,10.92690605,0.458191805,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,72008,DB00455,10016322,182,9219,58,5060,0.000223619,1.722245346,1.272261641,2.361303621,0.001581976,DB0045510016322_,6.44908034,0.543628873,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,72009,DB00005,10019708,72,128010,31,42388,0.253565887,0.769078393,0.49819059,1.212787686,0.414055394,DB0000510019708_,0.881755513,-0.262562374,NA,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,etanercept,DB00005
,72012,DB00455,10022061,73,9328,11,5107,8.82600510843864e-06,3.633101164,1.913625174,7.605109943,9.73731560442013e-05,DB0045510022061_,9.236959991,1.290086599,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,72013,DB00455,10042674,64,9337,28,5090,0.381493126,1.246067302,0.786433067,2.020914481,0.551585402,DB0045510042674_,0.594958598,0.219992433,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,72014,DB00338,10053425,125,33549,28,22244,1.70107228127053e-08,2.959879342,1.951368854,4.635457292,3.6189951366407e-07,DB0033810053425_,14.83189925,1.085148505,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,72015,DB00404,10053425,62,19830,10,9852,0.000363864,3.080208332,1.566960976,6.741701244,0.002369126,DB0040410053425_,6.045234176,1.124997235,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,72017,DB00338,10060795,135,33539,87,22185,0.890812819,1.026418176,0.777734129,1.360562193,0.954680373,DB0033810060795_,0.046378682,0.026075243,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,omeprazole,DB00338
,72018,DB00193,10001053,50,19270,40,8662,0.008302168,0.561921661,0.363039616,0.87470135,0.030675076,DB0019310001053_,3.484304812,-0.576392831,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,72019,DB00404,10001053,51,19841,23,9839,0.804916678,1.099580721,0.65946249,1.886316701,0.894427482,DB0040410001053_,0.11157145,0.094928945,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,72020,DB01012,10005396,43,10589,44,8641,0.33111924,0.79750258,0.510920268,1.244009514,0.499837557,DB0101210005396_,0.693472119,-0.22627021,NA,10005396,Blood calcium increased,10022891,Investigations,Inv,cinacalcet,DB01012
,72021,DB01012,10038533,22,10610,33,8652,0.029343049,0.543663013,0.301732584,0.961686389,0.083251339,DB0101210038533_,2.485891066,-0.609425686,NA,10038533,Renal transplant,10042613,Surgical and medical procedures,Surg,cinacalcet,DB01012
,72030,DB00480,10007515,107,67321,166,67496,0.000423867,0.646259547,0.501928183,0.829205218,0.002687897,DB0048010007515_,5.918996246,-0.43655408,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,72046,DB00863,10029354,78,10595,65,5775,0.013670564,0.654072752,0.463813549,0.925067931,0.045681512,DB0086310029354_,3.086061606,-0.424536692,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,ranitidine,DB00863
,72074,DB00190,10000087,37,3260,29,4645,0.016922091,1.817722383,1.085406563,3.071081175,0.054210502,DB0019010000087_,2.914880632,0.597584279,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,carbidopa,DB00190
,72077,DB08934,10000087,49,4440,71,6133,0.852620623,0.953293677,0.647166803,1.394426531,0.927881964,DB0893410000087_,0.074850748,-0.047832262,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,sofosbuvir,DB08934
,72078,DB00190,10003549,130,3167,199,4475,0.493425808,0.923063842,0.730699347,1.162897196,0.656112172,DB0019010003549_,0.421423511,-0.080056879,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,72086,DB00695,10047942,342,27707,234,20294,0.445106286,1.070517211,0.902954299,1.270937083,0.613107231,DB0069510047942_,0.48921543,0.068141907,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,furosemide,DB00695
,72092,DB00364,10016173,99,2651,41,1359,0.276089175,1.237724128,0.846420865,1.838660958,0.439495405,DB0036410016173_,0.822128016,0.213274313,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sucralfate,DB00364
,72093,DB01175,10016173,378,10346,179,4713,0.675644195,0.961988468,0.800359178,1.159662563,0.803392371,DB0117510016173_,0.218912053,-0.038752816,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,72096,DB01591,10028813,82,1873,14,642,0.015923287,2.007213511,1.1210241,3.859849894,0.051648769,DB0159110028813_,2.96328892,0.696747447,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,solifenacin,DB01591
,72098,DB00924,10029331,122,10040,45,4206,0.495786492,1.135736137,0.79906981,1.639517778,0.65811923,DB0092410029331_,0.418369163,0.127281019,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,72099,DB01175,10029331,87,10637,45,4847,0.5097705,0.880983496,0.606812777,1.294449642,0.670317796,DB0117510029331_,0.400003357,-0.126716387,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,72121,DB00512,10024515,65,4672,71,5027,1,0.98505639,0.690914167,1.402445561,1,DB0051210024515_,0,-0.015056391,NA,10024515,Linear IgA disease,10040785,Skin and subcutaneous tissue disorders,Skin,vancomycin,DB00512
,72122,DB00230,10074903,698,18976,233,8418,0.000166372,1.328969758,1.141480529,1.551525733,0.001233784,DB0023010074903_,6.697669426,0.284404024,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,72126,DB00297,10013968,33,1639,20,859,0.661682429,0.864822148,0.478422165,1.600825555,0.793698839,DB0029710013968_,0.231051186,-0.145231402,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupivacaine,DB00297
,72135,DB00327,10022437,107,6031,65,4197,0.43448369,1.145515403,0.831681115,1.588260403,0.60302719,DB0032710022437_,0.505792993,0.135854669,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,hydromorphone,DB00327
,72143,DB00181,10046555,47,9809,57,5814,0.000328001,0.48874837,0.32448494,0.733072496,0.002171536,DB0018110046555_,6.13232032,-0.715907503,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,baclofen,DB00181
,72157,DB00297,10070863,61,1611,42,837,0.170265649,0.754700484,0.496371414,1.156772257,0.311204546,DB0029710070863_,1.167304879,-0.281434318,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,bupivacaine,DB00297
,72158,DB00327,10070863,244,5894,173,4089,0.839030569,0.978471218,0.798588447,1.200937066,0.917498793,DB0032710070863_,0.086104014,-0.021763907,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,hydromorphone,DB00327
,72160,DB00575,10070863,176,5068,141,3688,0.417928186,0.908349397,0.720642452,1.146602588,0.586975281,DB0057510070863_,0.532772571,-0.096126176,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,clonidine,DB00575
,72195,DB00734,10001497,76,3974,127,4775,0.026830814,0.719071225,0.532166974,0.966174696,0.077627732,DB0073410001497_,2.555830549,-0.329794866,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,72196,DB00734,10016322,41,4009,31,4871,0.056472249,1.606849591,0.981378984,2.655266578,0.136909525,DB0073410016322_,1.988434974,0.474275486,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,72202,DB08910,10016807,78,16666,93,17395,0.399759458,0.875400192,0.638950428,1.196615329,0.569645308,DB0891010016807_,0.562741378,-0.133074135,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,pomalidomide,DB08910
,72207,DB06403,10024774,61,21410,14,6647,0.343485844,1.352701772,0.747388293,2.620651554,0.512780452,DB0640310024774_,0.667907495,0.302103905,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,72210,DB08889,10070863,40,3125,56,3829,0.537293435,0.875226121,0.566644952,1.34086795,0.693481854,DB0888910070863_,0.366030206,-0.133273002,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,carfilzomib,DB08889
,72211,DB06282,10013968,88,1452,25,508,0.438385277,1.231383121,0.77189888,2.028246565,0.606790786,DB0628210013968_,0.499571217,0.208138026,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levocetirizine,DB06282
,72224,DB08932,10060945,75,19368,16,6581,0.091886984,1.592669688,0.918954339,2.9304456,0.19823937,DB0893210060945_,1.618280038,0.465411657,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,72231,DB09401,10011906,36,724,54,706,0.064145207,0.650279412,0.408789856,1.02393125,0.150912912,DB0940110011906_,1.891052352,-0.430353144,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,isosorbide,DB09401
,72234,DB05259,10048334,72,11198,17,2711,1,1.025354154,0.59694868,1.859067067,1,DB0525910048334_,0,0.025038069,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,glatiramer,DB05259
,72236,DB05259,10060933,73,11197,18,2710,0.894950233,0.981562793,0.578677845,1.750529727,0.955976233,DB0525910060933_,0.045022227,-0.018609291,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,72239,DB06228,10019196,63,15849,74,16002,0.392827076,0.859574771,0.603894999,1.220301988,0.562802698,DB0622810019196_,0.57482616,-0.151317464,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,72240,DB01222,10047571,70,9204,21,5384,0.006191543,1.949794844,1.181382078,3.347826292,0.024268522,DB0122210047571_,3.718575165,0.667724159,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,budesonide,DB01222
,72242,DB01222,10061623,35,9239,19,5386,0.888000564,1.073882639,0.596999068,1.989373999,0.953608851,DB0122210061623_,0.047501701,0.071280715,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,72244,DB00364,10003658,38,2712,17,1383,0.774285267,1.139856354,0.625327969,2.16195953,0.876867223,DB0036410003658_,0.131399697,0.130902249,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,sucralfate,DB00364
,72245,DB01156,10003658,53,13569,44,6284,0.005910603,0.557888625,0.366516124,0.852846883,0.023392338,DB0115610003658_,3.755346751,-0.583595934,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,bupropion,DB01156
,72248,DB00364,10013573,113,2637,53,1347,0.675459593,1.089067053,0.773572232,1.549698915,0.8032946,DB0036410013573_,0.219033759,0.085321415,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sucralfate,DB00364
,72249,DB04868,10013573,38,1603,35,1481,1,1.003082589,0.613274752,1.644933071,1,DB0486810013573_,0,0.003077848,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,nilotinib,DB04868
,72254,DB00215,10024855,76,11027,35,5241,0.919151814,1.032020779,0.681902776,1.589683416,0.964291834,DB0021510024855_,0.036361298,0.031518802,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,72256,DB00706,10024855,12,1063,116,15809,0.145846568,1.538420865,0.770096152,2.802968864,0.278249105,DB0070610024855_,1.279238506,0.430756478,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,72260,DB00476,10033557,145,17112,34,6143,0.026474774,1.530891072,1.046416989,2.297555111,0.076807715,DB0047610033557_,2.566450185,0.425849966,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,duloxetine,DB00476
,72262,DB01156,10033557,89,13533,19,6309,0.001212665,2.183676951,1.318400134,3.799729964,0.006456983,DB0115610033557_,5.042593125,0.781010131,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,bupropion,DB01156
,72264,DB00641,10013781,73,14051,53,12422,0.284316238,1.217664585,0.842509543,1.770113453,0.448790074,DB0064110013781_,0.801200042,0.19693475,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,72266,DB01268,10028997,14,2129,41,3089,0.026343255,0.495497238,0.248825268,0.93066152,0.076520329,DB0126810028997_,2.570198841,-0.702193499,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sunitinib,DB01268
,72273,DB00646,10013950,43,3410,41,1959,0.022459942,0.602598817,0.382067534,0.951460204,0.067631984,DB0064610013950_,2.693674277,-0.506503616,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,nystatin,DB00646
,72274,DB00813,10013950,52,10520,45,10123,0.612517858,1.111934366,0.730906565,1.697408896,0.754417876,DB0081310013950_,0.281808852,0.10610117,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,72282,DB00904,10028116,87,22982,44,14412,0.280504929,1.239911454,0.852742244,1.825899727,0.444361734,DB0090410028116_,0.811116333,0.215039969,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,72292,DB08912,10061818,24,1306,30,1504,0.784898041,0.921284459,0.512642306,1.63935557,0.883247992,DB0891210061818_,0.124149266,-0.081986431,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,dabrafenib,DB08912
,72297,DB08932,10061024,301,19142,124,6473,0.071818514,0.820833441,0.662408893,1.022173569,0.164452448,DB0893210061024_,1.80513382,-0.197435063,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,macitentan,DB08932
,72304,DB01067,10053762,101,4260,84,4739,0.053211997,1.337528378,0.988348255,1.813941036,0.131057666,DB0106710053762_,2.032117856,0.290823417,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,glipizide,DB01067
,72307,DB00422,10013710,29,3406,42,2907,0.030978178,0.589373191,0.353087905,0.971502602,0.086882353,DB0042210013710_,2.443200342,-0.528695696,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,72309,DB00051,10016334,64,25667,27,11393,0.909585771,1.052151949,0.660961122,1.717401842,0.95941208,DB0005110016334_,0.041434599,0.050837542,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,72310,DB00051,10020642,98,25633,45,11375,0.856099644,0.96641892,0.671906924,1.40888912,0.930627756,DB0005110020642_,0.071895914,-0.034157874,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,72311,DB06404,10000060,60,3009,20,880,0.591365998,0.877379455,0.517998958,1.545653279,0.737769009,DB0640410000060_,0.304124499,-0.130815706,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,human c1-esterase inhibitor,DB06404
,72313,DB06404,10033371,44,3025,13,887,1,0.992449315,0.522124093,2.017907484,1,DB0640410033371_,0,-0.007579335,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,human c1-esterase inhibitor,DB06404
,72314,DB01240,10017944,70,5681,23,1553,0.446563627,0.832000377,0.511058105,1.401602136,0.614378321,DB0124010017944_,0.487144382,-0.183922384,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,72315,DB00524,10007882,46,1531,26,1318,0.094400362,1.522868904,0.916009728,2.581620763,0.20235903,DB0052410007882_,1.597711783,0.420595993,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,metolazone,DB00524
,72316,DB06228,10007882,89,15823,72,16004,0.179072808,1.250239549,0.905308033,1.731696307,0.32273501,DB0622810007882_,1.130923695,0.223335172,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,72323,DB01261,10037087,77,3704,50,3253,0.106326221,1.352429516,0.93205505,1.977671859,0.220678647,DB0126110037087_,1.511047721,0.301902616,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,sitagliptin,DB01261
,72325,DB08932,10024119,41,19402,11,6586,0.631889646,1.265200048,0.638199153,2.731032505,0.770695641,DB0893210024119_,0.260461743,0.23523025,NA,10024119,Left ventricular failure,10007541,Cardiac disorders,Card,macitentan,DB08932
,72336,DB00480,10000846,26,67402,44,67618,0.041360267,0.592808596,0.350369208,0.984391249,0.10845517,DB0048010000846_,2.22141837,-0.522883705,NA,10000846,Acute lymphocytic leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,72340,DB08911,10016256,81,1558,90,1658,0.81401057,0.957766827,0.694706697,1.318751662,0.900234312,DB0891110016256_,0.105100203,-0.043150927,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,trametinib,DB08911
,72341,DB08911,10047571,58,1581,48,1700,0.199803252,1.299177331,0.865241744,1.958612825,0.348802397,DB0891110047571_,1.053249716,0.261731242,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,trametinib,DB08911
,72342,DB01240,10007554,161,5590,55,1521,0.153341576,0.796516853,0.579741245,1.108415558,0.288651365,DB0124010007554_,1.242535668,-0.227506991,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,epoprostenol,DB01240
,72347,DB00788,10069327,38,9318,12,5049,0.104625874,1.715813392,0.876777192,3.610038671,0.217941205,DB0078810069327_,1.523529955,0.539887249,NA,10069327,Product quality issue,10077536,Product issues,Prod,naproxen,DB00788
,72351,DB00451,10066474,55,47216,16,15403,0.783298253,1.121392385,0.633035403,2.097350384,0.882057861,DB0045110066474_,0.125497624,0.114571114,NA,10066474,Thyroid cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levothyroxine,DB00451
,72360,DB00999,10003119,39,21391,28,12211,0.374464759,0.795128417,0.476652851,1.342362665,0.544342783,DB0099910003119_,0.608176115,-0.229251646,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,72361,DB06605,10003119,40,14033,42,12991,0.581802594,0.881668094,0.556866301,1.393938894,0.73006546,DB0660510003119_,0.314621078,-0.125939604,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,apixaban,DB06605
,72368,DB00904,10000084,59,23010,19,14437,0.010112568,1.948277352,1.144527924,3.462024842,0.035888593,DB0090410000084_,3.327335786,0.666945573,NA,10000084,Abdominal pain lower,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,72371,DB00073,10001760,71,7335,20,6387,2.19603966342055e-06,3.090797669,1.857814139,5.367494152,2.87894775825482e-05,DB0007310001760_,10.4555006,1.128429203,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,rituximab,DB00073
,72373,DB00531,10001760,74,7178,23,6493,1.87150075286533e-06,2.909965217,1.799092372,4.875630068,2.49834419954623e-05,DB0053110001760_,10.59729727,1.068141128,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,cyclophosphamide,DB00531
,72376,DB01234,10001760,338,31287,77,32811,1.2396890643652e-42,4.603007198,3.582327648,5.97855709,5.43087117613987e-40,DB0123410001760_,90.41130416,1.526709829,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,72378,DB00531,10002855,39,7213,20,6496,0.049126382,1.756086491,0.99844794,3.181464319,0.123348005,DB0053110002855_,2.092745607,0.563087749,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,cyclophosphamide,DB00531
,72380,DB00997,10002855,47,5284,8,3506,7.57234779597946e-05,3.897647678,1.821911939,9.56034231,0.000628082,DB0099710002855_,7.372839947,1.360373212,female,10002855,Anxiety,10037175,Psychiatric disorders,Psych,doxorubicin,DB00997
,72381,DB00073,10006002,32,7374,32,6375,0.615929434,0.864534432,0.51215326,1.459285046,0.757218268,DB0007310006002_,0.278103734,-0.145564146,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,rituximab,DB00073
,72383,DB00635,10006002,130,32923,73,23721,0.100949414,1.283074786,0.95554838,1.7341242,0.212217551,DB0063510006002_,1.550143346,0.249259374,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,72385,DB00904,10006002,156,22913,52,14404,4.23653930247813e-05,1.885883252,1.368675915,2.635530919,0.000383528,DB0090410006002_,7.866097203,0.63439628,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,72386,DB00997,10006002,71,5260,13,3501,1.64791998441923e-06,3.63469511,1.991559989,7.169855118,2.23910968159522e-05,DB0099710006002_,10.70684714,1.290525231,female,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,doxorubicin,DB00997
,72390,DB00635,10006784,128,32925,46,23748,2.83988210103985e-05,2.006991887,1.421887563,2.877155854,0.00027036,DB0063510006784_,8.215757426,0.696637027,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,72394,DB00541,10012174,36,3098,85,4212,0.005247673,0.575867796,0.377625207,0.862452014,0.021264948,DB0054110012174_,3.850695174,-0.551877165,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,vincristine,DB00541
,72396,DB00073,10015150,97,7309,66,6341,0.133900791,1.27502718,0.921281186,1.774067082,0.26116442,DB0007310015150_,1.342605109,0.242967496,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,rituximab,DB00073
,72398,DB00531,10015150,65,7187,28,6488,0.000800408,2.095472314,1.324392686,3.394838661,0.00457712,DB0053110015150_,5.38668535,0.739778976,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,cyclophosphamide,DB00531
,72400,DB00904,10015150,196,22873,80,14376,0.000978654,1.539841474,1.180350914,2.024800502,0.005409866,DB0090410015150_,5.219531007,0.431679472,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,72401,DB00997,10015150,61,5270,11,3503,8.9026369202264e-06,3.685642164,1.918627567,7.778297959,9.80950792069381e-05,DB0099710015150_,9.229573354,1.304444775,female,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,doxorubicin,DB00997
,72403,DB00099,10033371,88,2297,34,1921,9.43190732389568e-05,2.164145869,1.434103814,3.333011524,0.000758274,DB0009910033371_,7.184465761,0.772025766,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,filgrastim,DB00099
,72422,DB00904,10046543,62,23007,22,14434,0.024169579,1.768027382,1.071117225,3.02221601,0.071619118,DB0090410046543_,2.636393226,0.569864452,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,ondansetron,DB00904
,72423,DB01075,10046543,42,19906,22,11075,0.896467197,1.062153921,0.619453142,1.869207253,0.956301489,DB0107510046543_,0.044682051,0.060298847,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,diphenhydramine,DB01075
,72424,DB00722,10002383,29,25374,45,25987,0.081961,0.660021765,0.398917885,1.07633306,0.181632652,DB0072210002383_,1.705769028,-0.415482467,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,lisinopril,DB00722
,72427,DB00230,10007559,93,19581,57,8594,0.050539697,0.716091348,0.508992648,1.015077848,0.125995726,DB0023010007559_,2.071507297,-0.333947539,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,pregabalin,DB00230
,72429,DB00973,10008479,56,3795,46,2975,0.841073561,0.954325359,0.632558643,1.446122506,0.918820335,DB0097310008479_,0.084664676,-0.046750618,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,72438,DB00115,10022116,45,18380,18,10454,0.238189829,1.421909395,0.806356652,2.611404273,0.395778473,DB0011510022116_,0.926900636,0.352000612,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,72442,DB00158,10028596,90,16725,85,8019,1.04250738131756e-05,0.507662952,0.372739004,0.691995536,0.000112558,DB0015810028596_,9.092039672,-0.677937533,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,folic acid,DB00158
,72454,DB00115,10030095,113,18312,58,10414,0.57670912,1.10799081,0.799571952,1.549538716,0.72594398,DB0011510030095_,0.320282429,0.102548294,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,72455,DB00158,10030095,93,16722,32,8072,0.104042305,1.402894949,0.928790328,2.169218292,0.217116814,DB0015810030095_,1.527319755,0.338537922,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,72457,DB00331,10030095,110,24836,70,20682,0.08447796,1.308586502,0.960445065,1.793013015,0.185839493,DB0033110030095_,1.682871917,0.268947549,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,72461,DB11133,10048959,72,2359,22,1552,0.001254155,2.15276684,1.31319339,3.661687062,0.006626889,DB1113310048959_,5.016619836,0.766753917,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,72466,DB01101,10042609,36,7553,25,3883,0.278197873,0.7403539,0.431596017,1.288623612,0.441985621,DB0110110042609_,0.81647793,-0.300626964,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,capecitabine,DB01101
,72469,DB00005,10044654,63,128019,16,42403,0.434358732,1.3041811,0.744218816,2.41945067,0.602931943,DB0000510044654_,0.505950952,0.265575334,NA,10044654,Trigger finger,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,72474,DB00555,10069327,38,7009,20,3466,0.888814782,0.939569964,0.532241031,1.706978205,0.953896257,DB0055510069327_,0.047200359,-0.062332993,NA,10069327,Product quality issue,10077536,Product issues,Prod,lamotrigine,DB00555
,72475,DB00656,10069327,55,11958,35,6584,0.509072203,0.865231476,0.555598593,1.363655532,0.669550306,DB0065610069327_,0.401148977,-0.144758205,NA,10069327,Product quality issue,10077536,Product issues,Prod,trazodone,DB00656
,72476,DB00512,10037844,186,4551,214,4884,0.506962632,0.932735738,0.758975606,1.145549277,0.667610861,DB0051210037844_,0.404049819,-0.069633357,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,vancomycin,DB00512
,72478,DB00005,10019063,48,128034,15,42404,1,1.059800856,0.583363128,2.037887863,1,DB0000510019063_,0,0.058081019,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,72479,DB00005,10042772,115,127967,25,42394,0.062533401,1.523883722,0.982064548,2.452481868,0.148160308,DB0000510042772_,1.909460429,0.421262157,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,72480,DB00005,10052143,40,128042,10,42409,0.514049941,1.324829926,0.650996706,2.9714446,0.674039843,DB0000510052143_,0.394466055,0.281284094,NA,10052143,Ocular discomfort,10015919,Eye disorders,Eye,etanercept,DB00005
,72500,DB00331,10008111,20,24926,40,20712,0.001061932,0.415475727,0.230036877,0.727951751,0.005788653,DB0033110008111_,5.151855726,-0.878331085,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,metformin,DB00331
,72501,DB00641,10008111,39,14085,57,12418,0.018002715,0.603249995,0.390520586,0.923238931,0.056858312,DB0064110008111_,2.867192862,-0.505423583,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,72525,DB00227,10003988,65,2402,29,1774,0.026309001,1.655182322,1.04806585,2.671961081,0.076446174,DB0022710003988_,2.571168395,0.503911167,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lovastatin,DB00227
,72526,DB00956,10003988,139,5675,71,3396,0.312504968,1.171561142,0.871045329,1.587311534,0.479955189,DB0095610003988_,0.734062535,0.158337169,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocodone,DB00956
,72532,DB00761,10019301,37,15270,23,8602,0.689103291,0.906227279,0.524045964,1.59857376,0.81249806,DB0076110019301_,0.207641753,-0.098465144,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,72535,DB00999,10019301,53,21377,16,12223,0.023800539,1.893996161,1.065673478,3.551422112,0.070780921,DB0099910019301_,2.648165791,0.638688968,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,72571,DB00959,10020937,138,7940,44,4958,5.94066369429534e-05,1.958353982,1.382796355,2.821113399,0.000511298,DB0095910020937_,7.578558377,0.672104315,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,72572,DB00073,10046735,145,7261,93,6314,0.025623438,1.355760149,1.03540072,1.782536416,0.074888761,DB0007310046735_,2.591751449,0.304362293,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,rituximab,DB00073
,72577,DB00005,10041466,125,127957,36,42383,0.523245186,1.150095712,0.788117718,1.716330143,0.681574891,DB0000510041466_,0.383349143,0.139845167,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,72581,DB00005,10022076,47,128035,6,42413,0.024712768,2.594989947,1.107068287,7.428769285,0.072859076,DB0000510022076_,2.619228166,0.953582643,NA,10022076,Injection site infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,72594,DB00472,10037087,162,10597,42,4270,0.009968915,1.554208447,1.098641294,2.241808923,0.035476974,DB0047210037087_,3.338871412,0.440966378,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,fluoxetine,DB00472
,72596,DB00472,10042772,67,10692,26,4286,1,1.033009525,0.646884767,1.695614949,1,DB0047210042772_,0,0.032476411,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,72597,DB00736,10042772,81,10510,39,5514,0.700470942,1.089634875,0.733779674,1.642589015,0.819933687,DB0073610042772_,0.198531811,0.085842663,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,72601,DB00736,10060795,46,10545,17,5536,0.233989179,1.420526991,0.798103963,2.645674219,0.390812109,DB0073610060795_,0.939528374,0.351027923,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,esomeprazole,DB00736
,72605,DB01115,10028810,61,3539,14,2254,0.000283247,2.774645359,1.529738796,5.384210882,0.001926389,DB0111510028810_,6.252107815,1.02052294,female,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,nifedipine,DB01115
,72610,DB01060,10010774,158,8429,65,5016,0.011905667,1.446485087,1.074589094,1.966157364,0.040912596,DB0106010010774_,3.196317289,0.369136536,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,72618,DB01060,10041349,61,8526,34,5047,0.831753354,1.062036441,0.68601444,1.668996319,0.912102334,DB0106010041349_,0.092003086,0.060188236,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,amoxicillin,DB01060
,72631,DB00425,10074903,88,12607,46,7438,0.531191181,1.12869027,0.780476495,1.651299057,0.688072157,DB0042510074903_,0.373861568,0.121057907,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,72632,DB01202,10074903,22,6692,30,5688,0.095581286,0.623342497,0.342188013,1.118799518,0.204131961,DB0120210074903_,1.588988627,-0.472659156,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,levetiracetam,DB01202
,72633,DB00441,10033661,47,2227,39,1855,1,1.003821706,0.639435961,1.583656322,1,DB0044110033661_,0,0.003814422,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,gemcitabine,DB00441
,72634,DB00773,10033661,113,2210,173,2654,0.050643201,0.784443759,0.609082898,1.00717279,0.126172577,DB0077310033661_,2.070104652,-0.2427804,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,etoposide,DB00773
,72635,DB00958,10033661,109,4485,97,2488,0.001140756,0.623380373,0.467660863,0.832046875,0.006141903,DB0095810033661_,5.092620724,-0.472598395,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,carboplatin,DB00958
,72636,DB00958,10040047,132,4462,123,2462,4.77033465742841e-05,0.592161166,0.457321132,0.767270044,0.000424326,DB0095810040047_,7.76500922,-0.523976441,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,carboplatin,DB00958
,72661,DB00363,10047899,31,4597,31,6857,0.120293733,1.491534494,0.875575523,2.540957468,0.241774031,DB0036310047899_,1.419751745,0.399805452,NA,10047899,Weight increased,10022891,Investigations,Inv,clozapine,DB00363
,72662,DB00863,10047899,190,10483,77,5763,0.023979449,1.356495111,1.033489717,1.795115364,0.07119828,DB0086310047899_,2.642286613,0.304904249,NA,10047899,Weight increased,10022891,Investigations,Inv,ranitidine,DB00863
,72663,DB01020,10003549,69,1744,68,1810,0.794261525,1.053114113,0.737276663,1.504534679,0.888522299,DB0102010003549_,0.118195534,0.051751597,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,isosorbide mononitrate,DB01020
,72671,DB09068,10047899,71,2324,15,971,0.015768761,1.977311975,1.11514657,3.735780043,0.05126871,DB0906810047899_,2.970674656,0.681738334,NA,10047899,Weight increased,10022891,Investigations,Inv,vortioxetine,DB09068
,72675,DB01591,10013573,61,1894,26,630,0.314574381,0.780477312,0.480894333,1.298955102,0.48218962,DB0159110013573_,0.729417839,-0.247849607,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,solifenacin,DB01591
,72676,DB00268,10013709,205,2770,84,1461,0.062946512,1.28709396,0.985426519,1.69320291,0.148848077,DB0026810013709_,1.904829114,0.252386933,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,72680,DB00996,10013990,78,38875,43,22382,0.850650797,1.044372712,0.710490878,1.553270851,0.926255979,DB0099610013990_,0.076604647,0.04341643,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,72683,DB06637,10013990,62,6100,14,2005,0.230304334,1.455527639,0.803643494,2.821907306,0.386265278,DB0663710013990_,0.951230898,0.375368473,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,dalfampridine,DB06637
,72685,DB00268,10021097,66,2909,38,1507,0.602469572,0.899791187,0.591619008,1.385743053,0.746381968,DB0026810021097_,0.292517788,-0.105592557,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ropinirole,DB00268
,72686,DB00472,10021097,170,10589,96,4216,0.007541161,0.705073113,0.544297637,0.917680103,0.028406335,DB0047210021097_,3.561143078,-0.349453775,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,fluoxetine,DB00472
,72689,DB08908,10021097,61,10612,14,3265,0.412082655,1.340525804,0.740045984,2.598845413,0.581464764,DB0890810021097_,0.542204903,0.293061928,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,dimethyl fumarate,DB08908
,72705,DB00996,10061920,43,38910,32,22393,0.281377558,0.77335801,0.47793552,1.263167886,0.445341342,DB0099610061920_,0.80891423,-0.257013194,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,72726,DB01240,10024670,42,5709,11,1565,1,1.046687612,0.528060721,2.259640155,1,DB0124010024670_,0,0.045630522,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,epoprostenol,DB01240
,72750,DB00581,10011224,45,2068,29,2040,0.079071417,1.530552409,0.934719133,2.54228079,0.176816726,DB0058110011224_,1.732641529,0.425628722,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lactulose,DB00581
,72753,DB09153,10011224,232,7567,166,5533,0.877217614,1.021919878,0.831070574,1.258761666,0.947724572,DB0915310011224_,0.053691354,0.021683092,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,72767,DB09153,10011762,97,7702,82,5617,0.360701489,0.862710036,0.634924047,1.174596001,0.530600702,DB0915310011762_,0.633745514,-0.14767664,NA,10011762,Cystic fibrosis,10010331,"Congenital, familial and genetic disorders",Cong,sodium chloride,DB09153
,72770,DB00581,10013709,76,2037,71,1998,0.801414093,1.049933631,0.744996809,1.481165633,0.892535197,DB0058110013709_,0.11368933,0.048726954,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lactulose,DB00581
,72771,DB00684,10013709,46,2746,41,2307,0.828459359,0.942623605,0.602793036,1.478374248,0.909828169,DB0068410013709_,0.094499522,-0.059088222,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tobramycin,DB00684
,72775,DB00684,10013968,136,2656,122,2226,0.60835319,0.934305699,0.72136447,1.211055611,0.751034851,DB0068410013968_,0.286303222,-0.067951594,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tobramycin,DB00684
,72780,DB00448,10015150,57,5088,24,3100,0.135691489,1.446970445,0.881582072,2.443431622,0.26365927,DB0044810015150_,1.333097652,0.369472023,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,lansoprazole,DB00448
,72804,DB01234,10033318,64,31561,60,32828,0.590224335,1.109485193,0.767542439,1.605662752,0.736803453,DB0123410033318_,0.305434107,0.103896118,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,72845,DB00003,10070608,602,2396,475,2118,0.102634249,1.120296488,0.977999873,1.283804319,0.214975361,DB0000310070608_,1.537231858,0.113593372,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,dornase alfa,DB00003
,72846,DB00207,10070608,255,8825,222,5233,5.13592805133303e-05,0.68116266,0.564854799,0.821855878,0.000452178,DB0020710070608_,7.70143371,-0.383954146,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,azithromycin,DB00207
,72847,DB00434,10070608,50,565,43,515,0.829113338,1.059858719,0.678069001,1.662357014,0.910222971,DB0043410070608_,0.094065686,0.058135616,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,cyproheptadine,DB00434
,72848,DB00448,10070608,80,5065,48,3076,1,1.012173873,0.69692413,1.483761102,1,DB0044810070608_,0,0.012100367,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,lansoprazole,DB00448
,72850,DB00684,10070608,343,2449,324,2024,0.113371944,0.87494941,0.740951761,1.033298551,0.231149669,DB0068410070608_,1.46468986,-0.133589211,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,tobramycin,DB00684
,72854,DB09153,10070608,291,7508,256,5443,0.027203594,0.82409232,0.691683562,0.982285802,0.07844977,DB0915310070608_,2.545296728,-0.193472716,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,72855,DB08932,10020993,40,19403,17,6580,0.446511962,0.797934989,0.441841143,1.502143166,0.614343755,DB0893210020993_,0.487200646,-0.225728152,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,macitentan,DB08932
,72856,DB00820,10007815,80,11835,32,5784,0.36489302,1.22175994,0.800430782,1.905379208,0.534463404,DB0082010007815_,0.626492018,0.200292393,NA,10007815,Catheterisation cardiac,10022891,Investigations,Inv,tadalafil,DB00820
,72857,DB00612,10025482,33,1107,17,623,0.881438165,1.092417561,0.585709744,2.109209863,0.95045981,DB0061210025482_,0.050809401,0.088393186,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,bisoprolol,DB00612
,72865,DB00612,10028813,65,1075,26,614,0.145429981,1.427635147,0.882365479,2.370753215,0.277650556,DB0061210028813_,1.28139195,0.356019332,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,bisoprolol,DB00612
,72866,DB00471,10061428,196,13993,83,5382,0.459762356,0.908271324,0.697741131,1.191066662,0.627181853,DB0047110061428_,0.466518743,-0.09621213,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,montelukast,DB00471
,72869,DB01409,10061428,100,5931,68,3898,0.873684821,0.966489433,0.701200989,1.338994785,0.945073171,DB0140910061428_,0.056492924,-0.034084914,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,tiotropium,DB01409
,72872,DB00051,10047461,54,25677,33,11387,0.162384575,0.725673327,0.461841391,1.156014472,0.30056712,DB0005110047461_,1.20208419,-0.320655329,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,adalimumab,DB00051
,72878,DB00381,10003673,30,29330,28,22859,0.510132412,0.835048026,0.481946765,1.450982943,0.670606515,DB0038110003673_,0.399572729,-0.18026604,NA,10003673,Atrioventricular block complete,10007541,Cardiac disorders,Card,amlodipine,DB00381
,72894,DB00564,10019211,120,2484,29,1434,1.12301396475382e-05,2.38835859,1.571786014,3.73707481,0.000119969,DB0056410019211_,9.028275501,0.870606347,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,carbamazepine,DB00564
,72896,DB06285,10019211,383,8467,20,1086,1.54975551380733e-05,2.45607552,1.559567814,4.084891618,0.000159349,DB0628510019211_,8.744412785,0.898564759,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,teriparatide,DB06285
,72901,DB00316,10031282,106,65368,26,36927,5.62251824387334e-05,2.303072392,1.487960125,3.686855405,0.000488152,DB0031610031282_,7.624884578,0.834244054,NA,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,72917,DB01202,10061818,81,6633,78,5640,0.471271286,0.88300744,0.637600059,1.223500957,0.63748891,DB0120210061818_,0.450218398,-0.124421652,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,72919,DB00059,10005488,33,794,18,1089,0.001511594,2.513291608,1.363267581,4.77733933,0.00774357,DB0005910005488_,4.860892395,0.921593292,NA,10005488,Blood culture positive,10022891,Investigations,Inv,pegaspargase,DB00059
,72920,DB00541,10005488,43,3091,32,4265,0.009365286,1.853924664,1.143175315,3.034767127,0.033776969,DB0054110005488_,3.387976106,0.617304832,NA,10005488,Blood culture positive,10022891,Investigations,Inv,vincristine,DB00541
,72921,DB00563,10005488,37,46609,26,15322,0.004899622,0.4678106,0.275647258,0.804897468,0.020137061,DB0056310005488_,3.90519333,-0.759691766,NA,10005488,Blood culture positive,10022891,Investigations,Inv,methotrexate,DB00563
,72923,DB00987,10005488,35,2069,28,2900,0.02888092,1.751812168,1.031765666,2.999992922,0.082224052,DB0098710005488_,2.498307413,0.560650777,NA,10005488,Blood culture positive,10022891,Investigations,Inv,cytarabine,DB00987
,72954,DB01068,10002368,62,13701,39,6801,0.245694205,0.789159732,0.519716016,1.211304414,0.40457774,DB0106810002368_,0.904911372,-0.23678653,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,72956,DB01098,10016322,146,8003,88,7121,0.004445214,1.476203341,1.123122873,1.949756933,0.018592162,DB0109810016322_,3.985015174,0.389473482,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,72957,DB01068,10022998,108,13655,51,6789,0.800255731,1.052849703,0.746902768,1.501225191,0.892019927,DB0106810022998_,0.114266807,0.051500491,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,72958,DB01098,10022998,25,8124,30,7179,0.28038573,0.736417583,0.414859155,1.296697841,0.444239837,DB0109810022998_,0.811390688,-0.305957953,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,rosuvastatin,DB01098
,72960,DB09068,10033371,49,2346,8,978,0.011674544,2.55282321,1.193202809,6.265225654,0.04028162,DB0906810033371_,3.211859992,0.937199888,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,vortioxetine,DB09068
,72962,DB01068,10033864,48,13715,32,6808,0.193120436,0.744567817,0.465829781,1.204754514,0.340545462,DB0106810033864_,1.077206647,-0.29495134,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,72968,DB00398,10013786,35,692,55,1483,0.167422953,1.363614083,0.857446716,2.143463926,0.307441129,DB0039810013786_,1.179471659,0.310138589,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,sorafenib,DB00398
,72969,DB00398,10037844,79,648,105,1433,0.001288612,1.663456636,1.207855859,2.283851147,0.006778301,DB0039810037844_,4.994028791,0.508897748,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sorafenib,DB00398
,72972,DB00761,10044565,143,15164,66,8559,0.192862183,1.222874607,0.906134953,1.665029885,0.340227012,DB0076110044565_,1.078142203,0.201204323,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,72973,DB00178,10047700,50,1387,26,1654,0.000637591,2.292686011,1.391780718,3.858631533,0.003791218,DB0017810047700_,5.575067905,0.829724061,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ramipril,DB00178
,72981,DB01029,10011906,41,1299,32,869,0.545091826,0.857189122,0.52214075,1.418238504,0.69993838,DB0102910011906_,0.356762976,-0.154096705,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,irbesartan,DB01029
,73008,DB01261,10038423,25,3756,46,3257,0.002571716,0.471320668,0.276836319,0.785312234,0.011929333,DB0126110038423_,4.428754925,-0.752216594,NA,10038423,Renal cyst,10038359,Renal and urinary disorders,Renal,sitagliptin,DB01261
,73041,DB00186,10007515,184,16717,155,9853,0.001247427,0.699708017,0.561130587,0.87339346,0.006600629,DB0018610007515_,5.020590391,-0.357092149,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,lorazepam,DB00186
,73042,DB00363,10007515,40,4588,43,6845,0.144703125,1.387779563,0.877781632,2.189771527,0.276609696,DB0036310007515_,1.285147804,0.327705033,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,clozapine,DB00363
,73043,DB00999,10007515,82,21348,105,12134,4.11470881446832e-08,0.443891731,0.328101668,0.598796999,8.09241460443695e-07,DB0099910007515_,14.0271685,-0.812174594,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,73044,DB01050,10007515,154,17954,84,9287,0.731388751,0.948324009,0.721403131,1.253910396,0.843792803,DB0105010007515_,0.169848308,-0.053059053,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,ibuprofen,DB01050
,73045,DB09153,10007515,54,7745,85,5614,8.50286308932241e-06,0.460518095,0.320623132,0.656532206,9.42432031637527e-05,DB0915310007515_,9.269631849,-0.775403129,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,sodium chloride,DB09153
,73046,DB00363,10021097,31,4597,44,6844,0.906044472,1.048894884,0.639339992,1.701883169,0.958056921,DB0036310021097_,0.042848086,0.047737118,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,clozapine,DB00363
,73047,DB01050,10021097,234,17874,163,9208,0.003927321,0.739594722,0.601936288,0.91038146,0.016823605,DB0105010021097_,4.084972303,-0.301652916,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ibuprofen,DB01050
,73048,DB09153,10021097,151,7648,166,5533,0.000276729,0.658118755,0.52293692,0.82773432,0.001890039,DB0915310021097_,6.271157559,-0.418369885,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sodium chloride,DB09153
,73053,DB06228,10065154,48,15864,44,16032,0.676897871,1.102450092,0.71648247,1.700061668,0.804024607,DB0622810065154_,0.218125404,0.097535059,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,rivaroxaban,DB06228
,73060,DB00734,10063829,202,3848,275,4627,0.201879721,0.883268171,0.729115448,1.068583394,0.35126488,DB0073410063829_,1.046214695,-0.12412642,NA,10063829,Device malfunction,10077536,Product issues,Prod,risperidone,DB00734
,73062,DB00734,10070245,27,4023,58,4844,0.011849262,0.560554385,0.340616284,0.901418701,0.040766735,DB0073410070245_,3.199888843,-0.578829011,NA,10070245,Foreign body,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,73070,DB00422,10047895,92,3343,45,2904,0.001725476,1.775810208,1.225565286,2.605486926,0.008606098,DB0042210047895_,4.755284213,0.574256774,NA,10047895,Weight decreased,10022891,Investigations,Inv,methylphenidate,DB00422
,73071,DB01238,10047895,67,5183,31,3471,0.097230456,1.447333831,0.929954381,2.297883807,0.20668008,DB0123810047895_,1.576583186,0.369723127,NA,10047895,Weight decreased,10022891,Investigations,Inv,aripiprazole,DB01238
,73072,DB00422,10047899,64,3371,45,2904,0.332877139,1.225155528,0.820876148,1.842066376,0.501874246,DB0042210047899_,0.689405697,0.203067798,NA,10047899,Weight increased,10022891,Investigations,Inv,methylphenidate,DB00422
,73087,DB08908,10061024,37,10636,13,3266,0.738012737,0.873959678,0.453381397,1.794016761,0.849105524,DB0890810061024_,0.163571808,-0.134721039,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,dimethyl fumarate,DB08908
,73095,DB00863,10053762,383,10290,197,5643,0.479786485,1.066173823,0.892643647,1.276604261,0.644617806,DB0086310053762_,0.439097686,0.064076374,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,73096,DB06285,10020751,60,8790,6,1100,0.843282127,1.251366403,0.540728274,3.553277836,0.920520389,DB0628510020751_,0.082816128,0.224236077,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,teriparatide,DB06285
,73097,DB01609,10037844,42,1542,39,1304,0.734786305,0.910735075,0.570958481,1.455676136,0.846669856,DB0160910037844_,0.16644444,-0.093503231,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,deferasirox,DB01609
,73099,DB00476,10042458,1078,16179,403,5774,0.446261202,0.954637555,0.847182731,1.077303813,0.614086626,DB0047610042458_,0.487619275,-0.046423534,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,73105,DB01238,10028334,80,5170,25,3477,0.000593351,2.151927869,1.355361578,3.527654387,0.003563221,DB0123810028334_,5.63709024,0.766364124,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,aripiprazole,DB01238
,73110,DB00073,10005750,39,7367,18,6389,0.032324428,1.878945181,1.048361939,3.492964357,0.089795772,DB0007310005750_,2.410217388,0.630710546,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,rituximab,DB00073
,73112,DB00073,10008469,96,7310,47,6360,0.001282643,1.777028167,1.23883783,2.579985691,0.00675141,DB0007310008469_,4.998003932,0.5749424,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,73121,DB00706,10010264,20,1055,163,15762,0.020268127,1.833016583,1.086258576,2.939779767,0.062452108,DB0070610010264_,2.773355288,0.605963016,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,73124,DB00051,10013700,1101,24630,201,11219,3.19541098659755e-38,2.495008097,2.141238835,2.919515989,1.19136706074775e-35,DB0005110013700_,80.41537682,0.914291975,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,adalimumab,DB00051
,73126,DB01076,10022093,93,25654,21,25562,5.18579887678334e-12,4.412341909,2.72469503,7.464514257,2.09222906333461e-10,DB0107610022093_,22.28762089,1.484405594,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,73129,DB00065,10042674,44,9420,15,4942,0.170031089,1.538867278,0.839051165,2.98014578,0.310916357,DB0006510042674_,1.168231353,0.431046612,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,73133,DB00627,10003239,46,1283,26,1573,0.001689709,2.168583071,1.304372719,3.676233963,0.008463842,DB0062710003239_,4.771952099,0.774073992,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,niacin,DB00627
,73140,DB09270,10003988,105,3009,56,2312,0.029307453,1.440582631,1.026813857,2.03940385,0.083172794,DB0927010003988_,2.486834984,0.365047637,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ubidecarenone,DB09270
,73142,DB09270,10008479,49,3065,34,2334,0.738161687,1.097467591,0.691778823,1.759121071,0.849221138,DB0927010008479_,0.163435658,0.093005335,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,73143,DB00627,10010774,30,1299,27,1572,0.284456691,1.344476522,0.768145214,2.363856978,0.44895906,DB0062710010774_,0.800823576,0.296004734,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,niacin,DB00627
,73144,DB00930,10010774,49,1241,24,618,1,1.016712018,0.605385169,1.749927247,1,DB0093010010774_,0,0.016573909,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,colesevelam,DB00930
,73145,DB09270,10010774,96,3018,71,2297,0.874280211,1.029090904,0.745520601,1.426124381,0.945503203,DB0927010010774_,0.056038003,0.028675795,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ubidecarenone,DB09270
,73158,DB09270,10029331,62,3052,46,2322,0.922161607,1.025440766,0.686185904,1.54202345,0.965678685,DB0927010029331_,0.034924125,0.025122536,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,ubidecarenone,DB09270
,73160,DB00316,10031161,237,65237,68,36885,2.35091191152567e-07,1.970571372,1.498532434,2.620926012,3.92638994816513e-06,DB0031610031161_,12.44779014,0.678323537,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,73163,DB06643,10031161,140,52281,16,7499,0.467294117,1.25505947,0.74576705,2.257670903,0.633837804,DB0664310031161_,0.455962187,0.227182958,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,73165,DB00627,10033371,47,1282,39,1560,0.098648427,1.466248212,0.932046234,2.318049587,0.208846468,DB0062710033371_,1.566155902,0.382706902,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,niacin,DB00627
,73169,DB00169,10043255,47,38644,8,18167,0.005415038,2.761864741,1.292674507,6.769162669,0.02179865,DB0016910043255_,3.825907239,1.015906082,female,10043255,Tendonitis,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,73182,DB09270,10048959,88,3026,51,2317,0.119429126,1.321136139,0.921058165,1.912174141,0.240468389,DB0927010048959_,1.425166637,0.278492078,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,73191,DB06643,10052904,159,52262,20,7495,0.651901149,1.140155819,0.713374366,1.918326599,0.78617341,DB0664310052904_,0.240577888,0.131164936,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,73215,DB00112,10013709,132,5801,91,4000,1,1.000188397,0.7575374,1.325344216,1,DB0011210013709_,0,0.000188379,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,73216,DB00398,10013709,23,704,61,1477,0.404749246,0.791161164,0.463257431,1.309561679,0.574497607,DB0039810013709_,0.554259348,-0.234253585,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sorafenib,DB00398
,73217,DB00619,10028813,337,2562,188,2306,3.79680357328976e-07,1.613288298,1.333425013,1.956314775,6.03520584906635e-06,DB0061910028813_,12.01790059,0.478274517,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,imatinib,DB00619
,73221,DB00531,10039801,42,7210,53,6463,0.100026409,0.71037246,0.461598266,1.087050919,0.210807742,DB0053110039801_,1.556808737,-0.341965854,NA,10039801,Second primary malignancy,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyclophosphamide,DB00531
,73222,DB00541,10039801,25,3109,53,4244,0.083256102,0.643937823,0.382534062,1.057339664,0.183874914,DB0054110039801_,1.693499569,-0.440153106,NA,10039801,Second primary malignancy,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,vincristine,DB00541
,73223,DB00635,10039801,21,33032,38,23756,0.000530599,0.397446984,0.221543206,0.694851052,0.003239049,DB0063510039801_,5.732475393,-0.922693727,NA,10039801,Second primary malignancy,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,73247,DB00285,10013654,70,10881,90,3628,7.2733481487918e-17,0.259366407,0.186600239,0.359296586,5.50158147024439e-15,DB0028510013654_,32.8337408,-1.349513518,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,73248,DB00370,10013654,63,4478,84,3579,0.002487876,0.599477848,0.424105474,0.843693122,0.011621438,DB0037010013654_,4.45490381,-0.511696256,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,mirtazapine,DB00370
,73249,DB01238,10061428,32,5218,29,3473,0.23960332,0.73447368,0.429483559,1.260865184,0.397436233,DB0123810061428_,0.922720778,-0.308601118,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,aripiprazole,DB01238
,73257,DB00175,10007882,42,8089,43,6063,0.154461772,0.732130435,0.466312388,1.148677385,0.290064134,DB0017510007882_,1.237653228,-0.31179659,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,pravastatin,DB00175
,73262,DB00722,10040831,57,25346,43,25989,0.133972215,1.359196264,0.898508261,2.069463484,0.261264952,DB0072210040831_,1.342220244,0.306893543,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,73269,DB00916,10009657,61,5262,32,2399,0.574007675,0.869104306,0.556003205,1.381869584,0.723843396,DB0091610009657_,0.323180214,-0.140292131,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,metronidazole,DB00916
,73270,DB00916,10010264,88,5235,44,2387,0.636465415,0.911953106,0.625865833,1.34563378,0.774011911,DB0091610010264_,0.256168017,-0.092166709,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,73271,DB00916,10011906,104,5219,77,2354,0.001495315,0.609241474,0.447461995,0.832475773,0.007670637,DB0091610011906_,4.870355606,-0.49554058,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,73276,DB00814,10047513,65,8222,25,3390,0.816894285,1.071994966,0.665172837,1.778181208,0.901998164,DB0081410047513_,0.103142795,0.069521366,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,meloxicam,DB00814
,73296,DB00745,10019211,140,2437,43,1040,0.067590265,1.389343343,0.972452943,2.019449875,0.157017716,DB0074510019211_,1.851396637,0.32883122,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,modafinil,DB00745
,73299,DB00126,10019303,76,10095,28,5917,0.040899801,1.590885576,1.017867579,2.552358373,0.107450069,DB0012610019303_,2.230729016,0.464290827,NA,10019303,Heart rate increased,10022891,Investigations,Inv,ascorbic acid,DB00126
,73305,DB14513,10019303,39,7138,12,3552,0.179171002,1.617193525,0.8283115,3.396893894,0.322834508,DB1451310019303_,1.130615447,0.480692255,NA,10019303,Heart rate increased,10022891,Investigations,Inv,magnesium,DB14513
,73311,DB09072,10028735,40,6431,13,2522,0.647044474,1.20662119,0.630898911,2.463076365,0.782313016,DB0907210028735_,0.245500343,0.187824049,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium oxybate,DB09072
,73312,DB14513,10028735,55,7122,10,3554,0.002088805,2.744382577,1.383385882,6.046771629,0.010085274,DB1451310028735_,4.596678979,1.009556123,female,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium,DB14513
,73324,DB00745,10041349,71,2506,43,1040,0.060350917,0.685314724,0.45930971,1.032879214,0.144093365,DB0074510041349_,1.937293821,-0.377877094,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,modafinil,DB00745
,73325,DB00843,10041349,52,2142,61,2112,0.391518818,0.84055439,0.566302499,1.243669798,0.56136822,DB0084310041349_,0.577378224,-0.173693617,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,donepezil,DB00843
,73328,DB14513,10041349,77,7100,45,3519,0.385226561,0.848108456,0.578259031,1.256765264,0.555367137,DB1451310041349_,0.588125876,-0.164746755,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,73331,DB00153,10029148,35,7388,16,3423,1,1.013514634,0.545491598,1.963966458,1,DB0015310029148_,0,0.013424126,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,ergocalciferol,DB00153
,73332,DB00158,10029148,77,16738,30,8074,0.352947786,1.238056917,0.80158335,1.957826302,0.522705161,DB0015810029148_,0.64873772,0.213543148,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,folic acid,DB00158
,73335,DB00904,10029148,97,22972,62,14394,0.934965083,0.980300792,0.705008991,1.37186573,0.975259225,DB0090410029148_,0.025051972,-0.019895824,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,ondansetron,DB00904
,73336,DB01062,10029148,30,4456,29,1716,0.000641278,0.398444531,0.230304292,0.690254378,0.003809265,DB0106210029148_,5.570319114,-0.920186985,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,oxybutynin,DB01062
,73337,DB06724,10029148,50,7879,18,3901,0.300989323,1.375297729,0.787242593,2.508229129,0.467293013,DB0672410029148_,0.760798782,0.318670238,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,calcium carbonate,DB06724
,73338,DB00635,10020635,106,32947,146,23648,3.43334846653874e-07,0.521130175,0.401676201,0.674205564,5.51623254541386e-06,DB0063510020635_,12.10781544,-0.651755412,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,73343,DB00559,10025127,68,9591,26,3280,0.635200375,0.894423967,0.560531169,1.467317258,0.773299888,DB0055910025127_,0.257088353,-0.111575381,NA,10025127,Lung transplant,10042613,Surgical and medical procedures,Surg,bosentan,DB00559
,73350,DB00695,10001497,60,27989,47,20481,0.769076034,0.934154114,0.626789379,1.399550561,0.873508202,DB0069510001497_,0.13523776,-0.06811385,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,73352,DB00656,10007559,44,11969,44,6575,0.005206521,0.549384836,0.352973415,0.85501768,0.021135661,DB0065610007559_,3.856793568,-0.598956107,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,trazodone,DB00656
,73353,DB00537,10014387,30,7527,35,4263,0.004151102,0.485473481,0.28745147,0.815259427,0.017602923,DB0053710014387_,4.039690286,-0.722630614,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,ciprofloxacin,DB00537
,73354,DB00695,10014387,95,27954,52,20476,0.094802342,1.338192319,0.944024622,1.915404239,0.20293005,DB0069510014387_,1.59489394,0.291319688,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,furosemide,DB00695
,73373,DB00695,10040752,34,28015,26,20502,0.896367848,0.956972357,0.55730803,1.66125157,0.956301489,DB0069510040752_,0.044682051,-0.043980773,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,furosemide,DB00695
,73387,DB00203,10056819,70,13808,18,8920,0.000258363,2.512131305,1.478669486,4.485276384,0.001785715,DB0020310056819_,6.327936511,0.921131519,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,73389,DB00879,10013709,56,1721,170,3542,0.0134076,0.678009086,0.48928802,0.927651896,0.044968582,DB0087910013709_,3.101791209,-0.38859459,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,emtricitabine,DB00879
,73390,DB00879,10049414,23,1754,61,3651,0.349426389,0.784899255,0.461971879,1.291794795,0.519025352,DB0087910049414_,0.655802548,-0.242199907,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,emtricitabine,DB00879
,73392,DB00437,10037377,43,6878,98,11448,0.096818367,0.73032634,0.497341888,1.056908908,0.206008764,DB0043710037377_,1.579836567,-0.314263804,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,73394,DB00727,10037377,29,3814,34,4139,0.800987572,0.925602121,0.542911925,1.568665467,0.892358774,DB0072710037377_,0.113887015,-0.077310812,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nitroglycerin,DB00727
,73395,DB00787,10037377,182,16818,190,17058,0.794526507,0.971559345,0.787552994,1.198311958,0.888754638,DB0078710037377_,0.11793408,-0.028852926,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,73397,DB09140,10037377,53,3688,26,1772,0.904351655,0.979423893,0.599350218,1.637549385,0.957497529,DB0914010037377_,0.043432138,-0.020790745,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,73398,DB00005,10040914,123,127959,18,42401,0.00058325,2.264467822,1.374413726,3.947867268,0.003511392,DB0000510040914_,5.651742877,0.817339774,NA,10040914,Skin reaction,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,73404,DB00425,10007515,148,12547,102,7382,0.235698506,0.853693835,0.657778345,1.11155991,0.392855753,DB0042510007515_,0.934312774,-0.158182657,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,zolpidem,DB00425
,73405,DB00571,10007515,144,4979,66,2543,0.505863869,1.114349835,0.823601853,1.520949931,0.666698346,DB0057110007515_,0.405417591,0.108271127,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,propranolol,DB00571
,73410,DB00571,10021097,122,5001,68,2541,0.535469451,0.911601769,0.66940314,1.25012078,0.692045163,DB0057110021097_,0.368104062,-0.092552041,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,propranolol,DB00571
,73411,DB00425,10022523,100,12595,49,7435,0.307707661,1.204754634,0.846589049,1.734277025,0.474883857,DB0042510022523_,0.744685016,0.186275923,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,73412,DB00571,10022523,31,5092,40,2569,0.000116886,0.391050496,0.235913495,0.642706358,0.000911948,DB0057110022523_,6.999928059,-0.938918582,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,propranolol,DB00571
,73426,DB05332,10033371,40,989,15,772,0.018091125,2.080754841,1.114826621,4.086378788,0.057072158,DB0533210033371_,2.863438883,0.732730732,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,romiplostim,DB05332
,73432,DB00222,10047895,85,3121,77,3051,0.69075988,1.079092864,0.78003726,1.494845094,0.813470145,DB0022210047895_,0.206446052,0.076120748,NA,10047895,Weight decreased,10022891,Investigations,Inv,glimepiride,DB00222
,73433,DB01164,10013082,27,6497,36,7900,0.800028893,0.911936589,0.531907576,1.546432869,0.891918372,DB0116410013082_,0.114380662,-0.092184821,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,73442,DB00112,10017577,40,5893,48,4043,0.011781681,0.571772117,0.365453786,0.890247859,0.040579373,DB0011210017577_,3.2044954,-0.559014764,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,73445,DB00316,10023230,113,65361,50,36903,0.165337379,1.276025114,0.906727003,1.818116854,0.304590338,DB0031610023230_,1.188787558,0.243749867,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,73449,DB00316,10051608,56,65418,30,36923,0.910655651,1.05358075,0.664503921,1.700972934,0.95972831,DB0031610051608_,0.041105045,0.052194601,NA,10051608,Platelet count increased,10022891,Investigations,Inv,acetaminophen,DB00316
,73453,DB00472,10046735,101,10658,28,4284,0.09572074,1.449923412,0.944321223,2.293096636,0.20435899,DB0047210046735_,1.587877076,0.371510736,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,fluoxetine,DB00472
,73464,DB00455,10013781,71,9330,17,5101,0.001566417,2.28329208,1.329048764,4.14060652,0.00796465,DB0045510013781_,4.832742237,0.825618296,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,73465,DB00455,10016825,81,9320,23,5095,0.005150515,1.925163873,1.197364443,3.210444935,0.020943885,DB0045510016825_,3.86590854,0.655011093,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,loratadine,DB00455
,73466,DB00455,10020642,87,9314,34,5084,0.1046621,1.396690376,0.928096476,2.145172684,0.218008027,DB0045510020642_,1.523223397,0.334105421,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,loratadine,DB00455
,73467,DB00455,10029216,43,9358,17,5101,0.281756178,1.378740941,0.769247695,2.581307071,0.445766291,DB0045510029216_,0.807960477,0.321170721,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,loratadine,DB00455
,73469,DB06228,10013538,40,15872,39,16037,0.910597819,1.036311786,0.649450943,1.654932611,0.959686601,DB0622810013538_,0.041148505,0.03566805,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,73472,DB01068,10001540,32,13731,18,6822,0.654981446,0.883267785,0.480650583,1.672628603,0.788702261,DB0106810001540_,0.237366392,-0.124126857,NA,10001540,Akathisia,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,73478,DB06403,10008469,364,21107,74,6587,0.000653933,1.535019161,1.19066901,2.001780863,0.003872187,DB0640310008469_,5.553935773,0.428542864,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,73493,DB01285,10028813,66,1210,12,597,0.000757798,2.712458972,1.439640714,5.557751091,0.004371428,DB0128510028813_,5.432665492,0.997855593,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,corticotropin,DB01285
,73499,DB00958,10008531,60,4534,32,2553,0.913017437,1.055769408,0.674390563,1.680783121,0.961085319,DB0095810008531_,0.039692092,0.054269798,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,73519,DB14500,10028596,51,7758,54,4019,0.000388842,0.489284934,0.326391454,0.732593557,0.002505689,DB1450010028596_,5.989191529,-0.714810272,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,potassium,DB14500
,73522,DB14500,10035598,44,7765,38,4035,0.026013648,0.601694018,0.380264372,0.956116056,0.075745033,DB1450010035598_,2.580382404,-0.508006238,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,73524,DB00641,10037423,69,14055,56,12419,0.654352089,1.088754177,0.75350181,1.579006045,0.788179115,DB0064110037423_,0.238029911,0.085034086,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,73527,DB14500,10037423,53,7756,23,4050,0.544603757,1.203231148,0.723583312,2.060198379,0.6995167,DB1450010037423_,0.357365611,0.185010562,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,73528,DB00482,10047899,118,8141,23,3048,0.003009606,1.920773391,1.218393229,3.153563901,0.013546962,DB0048210047899_,4.301592966,0.652727913,NA,10047899,Weight increased,10022891,Investigations,Inv,celecoxib,DB00482
,73529,DB00734,10047899,114,3936,161,4741,0.218443107,0.85290708,0.662440879,1.095207871,0.37166842,DB0073410047899_,0.989753166,-0.159104671,NA,10047899,Weight increased,10022891,Investigations,Inv,risperidone,DB00734
,73535,DB00575,10003239,106,5138,50,3779,0.011025457,1.559185213,1.10067973,2.234402418,0.038470967,DB0057510003239_,3.257851421,0.444163385,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,clonidine,DB00575
,73537,DB00575,10003549,143,5101,104,3725,1,1.004091943,0.771635431,1.31017318,1,DB0057510003549_,0,0.004083594,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,73548,DB01175,10033371,401,10323,108,4784,3.00449275168105e-07,1.720648705,1.383872652,2.154271667,4.89452072996198e-06,DB0117510033371_,12.2273942,0.542701374,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,73558,DB01175,10048959,141,10583,54,4838,0.312401977,1.193636339,0.864691922,1.668447615,0.47991634,DB0117510048959_,0.734143481,0.177004395,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,73559,DB00425,10060933,49,12646,23,7461,0.394476084,1.256943286,0.750603796,2.163426354,0.56439615,DB0042510060933_,0.57199888,0.22868281,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,73562,DB00374,10005483,61,17655,30,5694,0.066084602,0.655793579,0.416545188,1.052989681,0.154306987,DB0037410005483_,1.868811236,-0.421909205,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,treprostinil,DB00374
,73563,DB00820,10005483,65,11850,38,5778,0.399960731,0.834066497,0.549828942,1.2811185,0.569854883,DB0082010005483_,0.562373542,-0.181442147,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,tadalafil,DB00820
,73564,DB01068,10005483,32,13731,35,6805,0.001591054,0.453125941,0.271350665,0.75430299,0.008060299,DB0106810005483_,4.820804623,-0.791585177,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,clonazepam,DB01068
,73565,DB06403,10005483,41,21430,22,6639,0.052098488,0.577366765,0.335679036,1.018507798,0.128958354,DB0640310005483_,2.048265766,-0.549277573,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,ambrisentan,DB06403
,73571,DB00682,10005851,37,19422,23,16341,0.299656621,1.353487483,0.782869601,2.386955674,0.465664033,DB0068210005851_,0.764290863,0.302684582,NA,10005851,Blood urea increased,10022891,Investigations,Inv,warfarin,DB00682
,73581,DB01118,10009033,23,3040,43,4666,0.527406722,0.821013138,0.471220679,1.396191667,0.68499287,DB0111810009033_,0.37834685,-0.197216167,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,73584,DB00374,10022595,69,17647,41,5683,0.002535809,0.541999038,0.362561342,0.819306061,0.011791903,DB0037410022595_,4.440342174,-0.612491053,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,treprostinil,DB00374
,73586,DB00820,10022595,35,11880,22,5794,0.396466603,0.775940726,0.442142564,1.389772539,0.566027084,DB0082010022595_,0.56911335,-0.253679146,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,tadalafil,DB00820
,73589,DB01118,10022595,35,3028,47,4662,0.570736505,1.146508578,0.716551077,1.819036828,0.721223482,DB0111810022595_,0.326806229,0.136721305,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,amiodarone,DB01118
,73592,DB00879,10035664,13,1764,38,3674,0.367028897,0.712559447,0.347371858,1.371742939,0.536659763,DB0087910035664_,0.622390974,-0.338891936,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,emtricitabine,DB00879
,73593,DB01118,10035664,152,2911,215,4494,0.443670573,1.091416627,0.876096534,1.357042416,0.611743257,DB0111810035664_,0.491442599,0.08747651,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,amiodarone,DB01118
,73595,DB00588,10040047,173,16351,93,8375,0.696603228,0.95280645,0.735232044,1.241282724,0.817493341,DB0058810040047_,0.201512522,-0.048343492,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,73597,DB01068,10040047,90,13673,50,6790,0.529276812,0.893887675,0.624926587,1.291285953,0.686570156,DB0106810040047_,0.376046865,-0.112175154,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,clonazepam,DB01068
,73598,DB01118,10040047,61,3002,72,4637,0.128745834,1.308583689,0.911908654,1.872687096,0.253841221,DB0111810040047_,1.371046322,0.268945399,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,amiodarone,DB01118
,73605,DB00230,10010071,49,19625,15,8636,0.276580846,1.437522136,0.792276103,2.761504509,0.440014982,DB0023010010071_,0.820946502,0.362920892,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,73609,DB00425,10010071,52,12643,11,7473,0.000954693,2.794055657,1.43913962,5.942378401,0.005302507,DB0042510010071_,5.239575522,1.027494181,female,10010071,Coma,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,73616,DB00351,10012735,64,602,82,782,1,1.013849961,0.706754042,1.449368044,1,DB0035110012735_,0,0.013754927,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,megestrol acetate,DB00351
,73617,DB00590,10012735,50,726,104,1848,0.269918716,1.223641426,0.845764408,1.751322911,0.432557825,DB0059010012735_,0.838039262,0.201831188,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,doxazosin,DB00590
,73618,DB11097,10012735,63,791,57,626,0.503826207,0.874787153,0.591896527,1.295128594,0.664946367,DB1109710012735_,0.408048892,-0.133774676,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,plantago seed,DB11097
,73619,DB11133,10012735,168,2263,92,1482,0.189519471,1.195805485,0.913731417,1.572744835,0.335934466,DB1113310012735_,1.090839179,0.178820005,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,omega-3 fatty acids,DB11133
,73620,DB00188,10019211,117,7769,78,8750,0.000381838,1.689336079,1.255557069,2.283531686,0.002466603,DB0018810019211_,6.004913401,0.524335599,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,73623,DB09270,10019211,162,2952,62,2306,1.20483486724775e-06,2.040828826,1.505751236,2.795699611,1.69082138203988e-05,DB0927010019211_,10.98771103,0.713356013,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ubidecarenone,DB09270
,73624,DB11097,10019211,37,817,15,668,0.022937678,2.015909469,1.069049439,3.989791494,0.068755486,DB1109710019211_,2.677198746,0.701070443,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,plantago seed,DB11097
,73625,DB11097,10028813,49,805,35,648,0.652118924,1.126851509,0.705963436,1.815035471,0.786384678,DB1109710028813_,0.240309194,0.119427468,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,plantago seed,DB11097
,73626,DB11133,10028813,169,2262,60,1514,2.6183151786973e-05,1.884963072,1.385370069,2.593665683,0.000251314,DB1113310028813_,8.288806307,0.63390823,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,omega-3 fatty acids,DB11133
,73627,DB00351,10035664,32,634,60,804,0.083667562,0.676510064,0.420621241,1.07070036,0.184535504,DB0035110035664_,1.689913399,-0.390807955,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,megestrol acetate,DB00351
,73628,DB09270,10035664,81,3033,96,2272,0.003273622,0.632113701,0.461960932,0.863140723,0.014521501,DB0927010035664_,4.232124892,-0.458685994,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ubidecarenone,DB09270
,73629,DB11097,10035664,32,822,36,647,0.169828268,0.699822037,0.415787858,1.173171383,0.310704963,DB1109710035664_,1.168911488,-0.356929209,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,plantago seed,DB11097
,73630,DB11133,10035664,78,2353,67,1507,0.084002979,0.745679331,0.527433801,1.056572823,0.185073409,DB1113310035664_,1.687002729,-0.293459622,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,omega-3 fatty acids,DB11133
,73631,DB00230,10038435,105,19569,67,8584,0.019799613,0.687448087,0.500671518,0.949517805,0.061313952,DB0023010038435_,2.791747853,-0.374768963,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,pregabalin,DB00230
,73632,DB00258,10038435,20,658,30,713,0.313524572,0.722556518,0.384844062,1.329817255,0.481029265,DB0025810038435_,0.731827169,-0.324959637,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,calcium acetate,DB00258
,73633,DB00370,10038435,39,4502,31,3632,1,1.014945902,0.615735354,1.686101898,1,DB0037010038435_,0,0.014835313,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,mirtazapine,DB00370
,73634,DB00425,10038435,88,12607,68,7416,0.096296478,0.761285138,0.547704465,1.062017362,0.205175936,DB0042510038435_,1.583887444,-0.272747303,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,zolpidem,DB00425
,73636,DB00706,10038435,12,1063,132,15793,0.301099403,1.350601233,0.678324371,2.449811539,0.467361798,DB0070610038435_,0.760651594,0.300549851,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,tamsulosin,DB00706
,73641,DB00425,10040070,22,12673,30,7454,0.003573722,0.431346313,0.236865828,0.77387742,0.015583031,DB0042510040070_,4.161572729,-0.840844001,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,zolpidem,DB00425
,73642,DB00497,10040070,66,19201,57,16318,0.928099257,0.984036266,0.679435387,1.429071337,0.970002941,DB0049710040070_,0.030456175,-0.016092527,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,oxycodone,DB00497
,73644,DB00706,10040070,8,1067,50,15875,0.028710782,2.3804242,0.972015989,5.076873514,0.081853136,DB0070610040070_,2.502828656,0.867278707,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,tamsulosin,DB00706
,73646,DB00996,10040070,99,38854,65,22360,0.417450812,0.876518121,0.634314133,1.218256264,0.586524192,DB0099610040070_,0.533541364,-0.131797901,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,gabapentin,DB00996
,73648,DB01136,10040070,28,9856,48,11067,0.083970961,0.655022121,0.395355643,1.066343699,0.185026129,DB0113610040070_,1.687258224,-0.423086272,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,carvedilol,DB01136
,73653,DB11133,10047895,59,2372,52,1522,0.114499041,0.728103914,0.490016553,1.084505066,0.232878655,DB1113310047895_,1.457237757,-0.317311502,NA,10047895,Weight decreased,10022891,Investigations,Inv,omega-3 fatty acids,DB11133
,73654,DB00370,10061428,118,4423,86,3577,0.476797933,1.10960298,0.830213268,1.488103063,0.642157087,DB0037010061428_,0.442922322,0.104002275,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,mirtazapine,DB00370
,73656,DB00715,10061428,70,4773,35,2252,0.833224263,0.943649924,0.618181903,1.463998414,0.913353341,DB0071510061428_,0.090632462,-0.058000024,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,paroxetine,DB00715
,73658,DB11133,10061428,43,2388,36,1538,0.247504055,0.76934959,0.480182394,1.239060661,0.406729859,DB1113310061428_,0.899606051,-0.26220981,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,omega-3 fatty acids,DB11133
,73666,DB00421,10009033,101,8802,49,5203,0.27045799,1.21836404,0.856291861,1.753971658,0.433167193,DB0042110009033_,0.836631499,0.197509008,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,73667,DB01104,10009033,90,15373,22,7264,0.004312115,1.932973832,1.200965961,3.239380198,0.018155364,DB0110410009033_,4.008789242,0.659059663,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,73670,DB13961,10009033,58,9399,43,6371,0.684615819,0.914299358,0.604891349,1.391467332,0.809548033,DB1396110009033_,0.21127917,-0.089597236,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,73677,DB00404,10027599,205,19687,22,9840,1.210434365239e-16,4.657850994,2.991620758,7.600532369,8.97496961644771e-15,DB0040410027599_,32.34433685,1.538554182,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,73679,DB00404,10039101,109,19783,23,9839,8.40921392473311e-05,2.356930346,1.491738151,3.876353179,0.00068805,DB0040410039101_,7.28164848,0.857360072,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,73683,DB00028,10044565,89,13369,34,5581,0.692744168,1.092752019,0.727429431,1.675855586,0.814932712,DB0002810044565_,0.204649731,0.088699302,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,73684,DB00864,10044565,169,6700,198,8194,0.710176843,1.043880407,0.842855553,1.291626864,0.827144445,DB0086410044565_,0.189775938,0.04294493,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,tacrolimus,DB00864
,73686,DB06643,10046571,407,52014,36,7479,0.003874394,1.625592879,1.153637314,2.356070616,0.016623971,DB0664310046571_,4.096909611,0.485872598,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,denosumab,DB06643
,73687,DB00231,10051055,38,3258,13,2126,0.044010416,1.907234927,0.991000708,3.911713546,0.113622553,DB0023110051055_,2.174873267,0.645654511,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,temazepam,DB00231
,73688,DB00188,10061024,34,7852,54,8774,0.109695836,0.703578677,0.443628539,1.10184465,0.225605809,DB0018810061024_,1.488966009,-0.351575572,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,bortezomib,DB00188
,73690,DB00425,10061024,52,12643,42,7442,0.134499413,0.728807634,0.475458216,1.123000552,0.261959438,DB0042510061024_,1.339565603,-0.316345458,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,zolpidem,DB00425
,73691,DB01068,10061024,49,13714,21,6819,0.613184103,1.160181256,0.682247762,2.038495827,0.754955461,DB0106810061024_,0.281096523,0.148576248,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,clonazepam,DB01068
,73692,DB06643,10061024,75,52346,11,7504,0.871195549,0.977410139,0.515883459,2.042356613,0.943115942,DB0664310061024_,0.058566054,-0.022848921,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,denosumab,DB06643
,73700,DB01050,10010305,160,17948,109,9262,0.027923213,0.757532857,0.589339616,0.976680427,0.080056805,DB0105010010305_,2.52501883,-0.277688367,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,73706,DB01050,10022052,103,18005,14,9357,6.83342007825895e-08,3.823180109,2.176882706,7.242202618,1.2825165780581e-06,DB0105010022052_,13.56668633,1.341082566,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,73707,DB00316,10022094,80,65394,15,36938,1.51506439989968e-05,3.012514028,1.721482484,5.633516747,0.000156324,DB0031610022094_,8.763581571,1.102774955,female,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,73710,DB00068,10027175,50,2184,7,658,0.056080437,2.151436792,0.964645765,5.652324875,0.136217186,DB0006810027175_,1.993504708,0.766135894,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,interferon beta-1b,DB00068
,73711,DB01050,10027175,193,17915,59,9312,0.000294034,1.700292688,1.262696999,2.318817666,0.001985287,DB0105010027175_,6.221991608,0.530800406,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,73712,DB01050,10029410,53,18055,29,9342,0.81608527,0.945630373,0.589984282,1.543588446,0.901407796,DB0105010029410_,0.10379752,-0.055903512,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,73718,DB01050,10049848,104,18004,61,9310,0.45866916,0.881634773,0.635952745,1.231352882,0.626080485,DB0105010049848_,0.468276346,-0.125977398,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,73721,DB01050,10062355,82,18026,53,9318,0.203951151,0.799787407,0.558788908,1.15319926,0.353735137,DB0105010062355_,1.039206847,-0.223409327,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,73725,DB01137,10010264,114,7658,67,5526,0.197500506,1.227775143,0.898241126,1.689443865,0.345995506,DB0113710010264_,1.061329493,0.205203704,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,73726,DB06605,10010264,203,13870,116,12917,2.80589272121589e-05,1.629722336,1.289259792,2.068182051,0.000267706,DB0660510010264_,8.225622724,0.488409655,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,73727,DB09153,10010264,119,7680,78,5621,0.468257111,1.116644516,0.830413563,1.50858303,0.63478368,DB0915310010264_,0.454471,0.110328221,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,73729,DB06605,10019022,23,14050,40,12993,0.016116258,0.531758648,0.303740811,0.91050324,0.052114885,DB0660510019022_,2.954304671,-0.631565562,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,73732,DB06605,10038063,113,13960,122,12911,0.238798344,0.856635636,0.656523328,1.116971883,0.396526388,DB0660510038063_,0.925012687,-0.154742613,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,73742,DB01254,10002034,41,3426,46,3102,0.332534754,0.807041497,0.514998872,1.260790172,0.501473093,DB0125410002034_,0.690205326,-0.214380191,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,dasatinib,DB01254
,73745,DB00684,10012735,50,2742,46,2302,0.679963944,0.912552858,0.596633397,1.398492441,0.806445675,DB0068410012735_,0.215118743,-0.091509268,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,tobramycin,DB00684
,73746,DB00684,10028813,73,2719,24,2324,2.0415816138586e-05,2.599242966,1.61324566,4.326769384,0.000203384,DB0068410028813_,8.500412796,0.955220236,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,tobramycin,DB00684
,73775,DB01307,10008479,42,2482,31,2038,0.722514382,1.112419107,0.680111628,1.837669129,0.836639156,DB0130710008479_,0.178362417,0.10653702,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,insulin detemir,DB01307
,73776,DB06285,10008479,65,8785,12,1094,0.202721623,0.674574373,0.359716253,1.376698093,0.352183599,DB0628510008479_,1.043602651,-0.393673346,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,73777,DB14500,10008479,125,7684,59,4014,0.583839042,1.106731834,0.803734315,1.538919294,0.731764977,DB1450010008479_,0.312295886,0.101411378,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,73778,DB01307,10019211,82,2442,42,2027,0.013206412,1.620419329,1.098384349,2.421484136,0.044435552,DB0130710019211_,3.113715418,0.482684961,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,insulin detemir,DB01307
,73782,DB00563,10021519,116,46530,31,15317,0.339057883,1.231780309,0.822283534,1.895695523,0.508132531,DB0056310021519_,0.677012978,0.208460528,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,73785,DB00563,10029331,179,46467,84,15264,0.00803117,0.700003703,0.536823788,0.918951387,0.029875361,DB0056310029331_,3.51072119,-0.356669654,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,73790,DB01225,10061818,80,4964,58,4582,0.170463416,1.273133016,0.894394165,1.821805473,0.311479381,DB0122510061818_,1.166422135,0.241480804,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,73793,DB09072,10061284,32,6439,19,2516,0.160065255,0.658128252,0.361097184,1.231340293,0.297557567,DB0907210061284_,1.21214757,-0.418355455,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,73795,DB08890,10022437,37,1910,13,546,0.496216597,0.813681612,0.41912472,1.680621466,0.658507258,DB0889010022437_,0.417779735,-0.20618613,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,linaclotide,DB08890
,73798,DB00563,10020100,47,46599,11,15337,0.362598432,1.406240467,0.718619828,3.007572428,0.53220767,DB0056310020100_,0.630721509,0.340919808,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,73799,DB00404,10013887,55,19837,25,9837,0.812216864,1.090955702,0.668005343,1.828327083,0.89905753,DB0040410013887_,0.106408254,0.087054103,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,73800,DB00996,10013887,118,38835,74,22351,0.59938591,0.91775175,0.680193464,1.24508859,0.744048674,DB0099610013887_,0.295648824,-0.085828349,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,73801,DB01104,10013887,43,15420,16,7270,0.485926238,1.267015224,0.698749218,2.41144331,0.649960453,DB0110410013887_,0.430843759,0.236663917,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,73803,DB00996,10027599,339,38614,52,22373,6.86926703422364e-25,3.777179415,2.813107108,5.162749161,1.04068405760558e-22,DB0099610027599_,50.6169938,1.328977545,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,73805,DB00404,10043607,132,19760,58,9804,0.486724194,1.129166482,0.822338916,1.567013014,0.650633831,DB0040410043607_,0.429808266,0.121479734,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,alprazolam,DB00404
,73806,DB01104,10043607,103,15360,57,7229,0.349646456,0.850469186,0.608732285,1.198491781,0.519234864,DB0110410043607_,0.655398966,-0.161967099,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,sertraline,DB01104
,73807,DB00404,10044390,54,19838,24,9838,0.7187396,1.115804194,0.677585721,1.88853313,0.833911611,DB0040410044390_,0.181627864,0.109575395,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,73808,DB00404,10048334,69,19823,24,9838,0.151433676,1.426823995,0.88461772,2.376182704,0.285889117,DB0040410048334_,1.252151248,0.355450992,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,73809,DB01104,10048334,62,15401,23,7263,0.353421894,1.271199418,0.775722938,2.151778481,0.52320095,DB0110410048334_,0.647789663,0.239960879,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,73821,DB00181,10040984,34,9822,19,5852,0.887544686,1.066180348,0.590504141,1.980570385,0.953356575,DB0018110040984_,0.047766285,0.064082494,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,73830,DB00575,10020937,71,5173,36,3793,0.076516454,1.446034603,0.952938148,2.228756058,0.172357327,DB0057510020937_,1.758185477,0.368825053,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,73831,DB00327,10000059,60,6078,28,4234,0.082354563,1.492680919,0.936386903,2.43278541,0.182274308,DB0032710000059_,1.702242539,0.400573778,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,hydromorphone,DB00327
,73832,DB00181,10028391,55,9801,21,5850,0.095483796,1.563209272,0.929073663,2.724343802,0.20399298,DB0018110028391_,1.589669699,0.446740934,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,73833,DB06413,10002855,97,1459,32,642,0.19884973,1.33370439,0.87546959,2.07863319,0.347659153,DB0641310002855_,1.056532724,0.287960326,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,armodafinil,DB06413
,73835,DB09072,10013710,37,6434,14,2521,1,1.035560354,0.545673566,2.077393496,1,DB0907210013710_,0,0.034942685,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,73837,DB09072,10033557,76,6395,13,2522,0.004134745,2.305377634,1.267923239,4.535049534,0.017549132,DB0907210033557_,4.04275078,0.835244496,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,sodium oxybate,DB09072
,73840,DB00012,10000081,48,1598,31,1282,0.361539727,1.242107137,0.769509346,2.031400872,0.531398798,DB0001210000081_,0.632242507,0.216809241,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,darbepoetin alfa,DB00012
,73842,DB00319,10000081,40,1352,31,1822,0.028386613,1.738543001,1.054523958,2.890661172,0.081137682,DB0031910000081_,2.511607792,0.553047406,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,piperacillin,DB00319
,73844,DB00567,10000081,74,4445,21,2060,0.045824226,1.63297166,0.991329659,2.800192295,0.117134084,DB0056710000081_,2.144435983,0.490401459,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,cephalexin,DB00567
,73849,DB01275,10000081,46,3933,28,3321,0.197201278,1.387154656,0.846677365,2.310103373,0.345654547,DB0127510000081_,1.062315423,0.327254639,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,hydralazine,DB01275
,73857,DB00567,10002034,77,4442,32,2049,0.678243487,1.109931063,0.723385717,1.738761791,0.805061303,DB0056710002034_,0.216836852,0.104297908,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,cephalexin,DB00567
,73859,DB01190,10002034,37,4897,36,2249,0.002136779,0.472061265,0.289343833,0.770876011,0.01027256,DB0119010002034_,4.578278977,-0.750646504,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,clindamycin,DB01190
,73860,DB01202,10002034,66,6648,39,5679,0.076502699,1.445594776,0.956995006,2.209835397,0.172340885,DB0120210002034_,1.758280876,0.368520847,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,levetiracetam,DB01202
,73863,DB00012,10002855,36,1610,17,1296,0.071262229,1.704343229,0.927856765,3.251559643,0.16346312,DB0001210002855_,1.811167877,0.533179834,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,darbepoetin alfa,DB00012
,73867,DB00567,10002855,82,4437,18,2063,0.003186014,2.117917442,1.256271608,3.759506736,0.014209616,DB0056710002855_,4.253836334,0.750433267,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,cephalexin,DB00567
,73869,DB00687,10002855,38,948,24,1061,0.038063489,1.771559631,1.026887026,3.112163652,0.101738745,DB0068710002855_,2.28534708,0.571860306,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,fludrocortisone,DB00687
,73870,DB00813,10002855,124,10448,65,10103,5.27618553228422e-05,1.844636262,1.353822204,2.533431318,0.00046259,DB0081310002855_,7.678669031,0.61228211,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,fentanyl,DB00813
,73872,DB00927,10002855,135,7362,40,4976,1.69486809338164e-06,2.281025087,1.589004299,3.33922533,2.29297342838258e-05,DB0092710002855_,10.68307605,0.824624941,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,famotidine,DB00927
,73873,DB01202,10002855,132,6582,71,5647,0.001719434,1.594991343,1.183628167,2.164397489,0.008585738,DB0120210002855_,4.757652874,0.466868309,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,73874,DB01225,10002855,58,4986,32,4608,0.019566396,1.674996176,1.06755747,2.67088789,0.060756374,DB0122510002855_,2.800883275,0.515810882,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,enoxaparin,DB01225
,73875,DB01275,10002855,37,3942,18,3331,0.057355679,1.73681951,0.961980535,3.247190709,0.138463816,DB0127510002855_,1.977146247,0.552055573,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,hydralazine,DB01275
,73937,DB00567,10003988,113,4406,33,2048,0.019020251,1.591556451,1.067280487,2.431226931,0.059414972,DB0056710003988_,2.823209024,0.464712438,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cephalexin,DB00567
,73940,DB00916,10003988,84,5239,18,2413,0.002440318,2.149212437,1.277228819,3.809814676,0.011443004,DB0091610003988_,4.47037677,0.765101467,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,metronidazole,DB00916
,73941,DB00924,10003988,288,9874,98,4153,0.079322009,1.23600888,0.976533922,1.575404264,0.177286595,DB0092410003988_,1.729987676,0.211887543,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,73942,DB01202,10003988,77,6637,34,5684,0.0010804,1.93938565,1.27736483,3.000098374,0.005872408,DB0120210003988_,5.137490525,0.662371247,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,levetiracetam,DB01202
,73943,DB01225,10003988,86,4958,62,4578,0.15853609,1.280749512,0.910813814,1.809857549,0.295530026,DB0122510003988_,1.218984838,0.247445463,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,enoxaparin,DB01225
,74090,DB00285,10006093,65,10886,25,3693,0.626770162,0.882053947,0.547443031,1.462719813,0.766280445,DB0028510006093_,0.26620706,-0.125502061,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,venlafaxine,DB00285
,74093,DB00425,10006093,65,12630,20,7464,0.00939206,1.920606573,1.147400167,3.350552091,0.033858737,DB0042510006093_,3.38555821,0.652641059,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,zolpidem,DB00425
,74095,DB00497,10006093,32,19235,71,16304,3.61726682353386e-06,0.382035487,0.243378464,0.588005013,4.45443234746252e-05,DB0049710006093_,10.01902583,-0.962241776,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,oxycodone,DB00497
,74097,DB00683,10006093,33,1551,46,1592,0.210192101,0.736427194,0.453545371,1.184078935,0.361408761,DB0068310006093_,1.017745658,-0.305944903,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,midazolam,DB00683
,74099,DB00695,10006093,112,27937,108,20420,0.04038995,0.758014413,0.576349132,0.997299449,0.10641506,DB0069510006093_,2.240408173,-0.277052879,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,furosemide,DB00695
,74100,DB00813,10006093,76,10496,81,10087,0.522778072,0.901714645,0.649740642,1.250250975,0.68123201,DB0081310006093_,0.383852341,-0.103457167,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,fentanyl,DB00813
,74103,DB00924,10006093,38,10124,26,4225,0.054856358,0.609959668,0.360291443,1.047721484,0.13407405,DB0092410006093_,2.009363018,-0.494362443,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,cyclobenzaprine,DB00924
,74106,DB01202,10006093,47,6667,51,5667,0.262984476,0.783359561,0.514758693,1.189843933,0.424773217,DB0120210006093_,0.85619986,-0.244163479,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,levetiracetam,DB01202
,74107,DB01225,10006093,44,5000,42,4598,0.913821801,0.963382328,0.61543275,1.509935224,0.961426784,DB0122510006093_,0.039336865,-0.037304929,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,enoxaparin,DB01225
,74157,DB01225,10007559,38,5006,32,4608,0.720754183,1.093049344,0.663739561,1.810653688,0.835355337,DB0122510007559_,0.179898091,0.088971354,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,enoxaparin,DB01225
,74166,DB00316,10007636,50,65424,47,36906,0.01454267,0.600085023,0.394767292,0.913631878,0.048078234,DB0031610007636_,3.034925721,-0.510683929,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,74180,DB00996,10007636,34,38919,21,22404,0.781347698,0.932018231,0.525452216,1.690305114,0.880918086,DB0099610007636_,0.126790636,-0.070402904,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,gabapentin,DB00996
,74182,DB01136,10007636,42,9842,32,11083,0.102797152,1.477956172,0.910209093,2.420976762,0.215206335,DB0113610007636_,1.536158015,0.390660169,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,carvedilol,DB01136
,74191,DB00285,10007882,43,10908,18,3700,0.461620774,0.810309355,0.456949877,1.494658324,0.628868436,DB0028510007882_,0.463833208,-0.210339184,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,venlafaxine,DB00285
,74193,DB00399,10007882,37,6955,28,4970,0.899743781,0.944304277,0.561588876,1.604228407,0.956571579,DB0039910007882_,0.044399659,-0.057306837,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,zoledronic acid,DB00399
,74196,DB00497,10007882,119,19148,99,16276,0.891752489,1.021731429,0.775353199,1.348875283,0.955008248,DB0049710007882_,0.046035302,0.021498668,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,oxycodone,DB00497
,74197,DB00567,10007882,106,4413,58,2023,0.307079015,0.837837164,0.599889781,1.180044722,0.474148534,DB0056710007882_,0.746234644,-0.176931513,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,cephalexin,DB00567
,74199,DB00813,10007882,52,10520,33,10135,0.064641606,1.518052561,0.962045852,2.426313602,0.151827385,DB0081310007882_,1.885011029,0.417428304,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,fentanyl,DB00813
,74202,DB00924,10007882,74,10088,23,4228,0.221368959,1.348375223,0.833418247,2.259810252,0.375210736,DB0092410007882_,0.980267449,0.298900329,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,cyclobenzaprine,DB00924
,74245,DB00188,10009657,20,7866,32,8796,0.214205627,0.698910626,0.378492339,1.261259546,0.366514445,DB0018810009657_,1.003717345,-0.358232405,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,bortezomib,DB00188
,74246,DB00264,10009657,56,29551,30,24862,0.050790162,1.570456947,0.99035358,2.535903409,0.126476189,DB0026410009657_,2.067701215,0.451366626,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,metoprolol,DB00264
,74253,DB00480,10009657,133,67295,97,67565,0.017410879,1.376626521,1.051454241,1.807715533,0.055428446,DB0048010009657_,2.892662359,0.319635957,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,74255,DB00682,10009657,40,19419,23,16341,0.164056462,1.463451878,0.854813386,2.561769451,0.302814094,DB0068210009657_,1.194636214,0.380797945,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,warfarin,DB00682
,74266,DB01234,10009657,82,31543,80,32808,0.694732914,1.066137662,0.773543478,1.469780083,0.816264204,DB0123410009657_,0.203017197,0.064042456,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,74281,DB00480,10010214,69,67359,80,67582,0.412589042,0.865357025,0.617737044,1.20951863,0.582057909,DB0048010010214_,0.541185336,-0.144613112,NA,10010214,Compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,74299,DB01234,10010214,39,31586,40,32848,1,1.013956955,0.635134779,1.617496475,1,DB0123410010214_,0,0.013860453,NA,10010214,Compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,74361,DB00683,10011906,50,1534,35,1603,0.078588075,1.492634799,0.944022941,2.383164688,0.175960437,DB0068310011906_,1.737496101,0.40054288,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,midazolam,DB00683
,74362,DB00687,10011906,43,943,99,986,1.71459665041697e-05,0.454312227,0.306421951,0.664198666,0.000174379,DB0068710011906_,8.654281233,-0.788970593,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,fludrocortisone,DB00687
,74363,DB00878,10011906,37,1149,46,874,0.031721479,0.611993101,0.38229675,0.973777206,0.088480828,DB0087810011906_,2.424969386,-0.491034269,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,chlorhexidine,DB00878
,74364,DB01190,10011906,77,4857,67,2218,0.000184889,0.524847387,0.371814016,0.742427704,0.001349573,DB0119010011906_,6.607967136,-0.644647751,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,clindamycin,DB01190
,74365,DB01275,10011906,176,3803,194,3155,0.008618476,0.752669494,0.606799678,0.933066169,0.031610501,DB0127510011906_,3.454265914,-0.284129066,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,74370,DB00012,10012174,40,1606,10,1303,0.000449695,3.244106566,1.586700632,7.304744274,0.002826793,DB0001210012174_,5.868612468,1.176839986,female,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,darbepoetin alfa,DB00012
,74374,DB00567,10012174,63,4456,25,2056,0.565434139,1.162692898,0.718584497,1.934991261,0.717022209,DB0056710012174_,0.332648464,0.150738778,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,cephalexin,DB00567
,74378,DB00916,10012174,68,5255,28,2403,0.739939304,1.11051601,0.703375922,1.796484775,0.850503087,DB0091610012174_,0.161927237,0.104824781,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,metronidazole,DB00916
,74379,DB00924,10012174,109,10053,42,4209,0.719864427,1.08656943,0.753117109,1.593470071,0.834673745,DB0092410012174_,0.180714355,0.083025421,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,cyclobenzaprine,DB00924
,74380,DB01225,10012174,102,4942,95,4545,0.942670159,0.987432954,0.737045276,1.323897221,0.981718542,DB0122510012174_,0.018450629,-0.012646679,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,enoxaparin,DB01225
,74381,DB01275,10012174,58,3921,47,3302,0.921470153,1.039228593,0.693075622,1.5653643,0.965261115,DB0127510012174_,0.035356629,0.038478701,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,hydralazine,DB01275
,74397,DB00480,10012318,37,67391,33,67629,0.634667486,1.125170283,0.684481709,1.856677165,0.772844497,DB0048010012318_,0.257677419,0.117934387,NA,10012318,Dental caries,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,74422,DB00188,10012378,35,7851,28,8800,0.206423473,1.401057475,0.82720439,2.393322178,0.356974966,DB0018810012378_,1.030089623,0.33722729,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,bortezomib,DB00188
,74425,DB00399,10012378,71,6921,36,4962,0.094645624,1.413940838,0.932349857,2.178011136,0.202713573,DB0039910012378_,1.595961265,0.346380726,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,zoledronic acid,DB00399
,74431,DB00927,10012378,97,7400,44,4972,0.030821524,1.48117075,1.02505702,2.170127891,0.08654319,DB0092710012378_,2.447111687,0.392832822,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,famotidine,DB00927
,74433,DB01202,10012378,126,6588,92,5626,0.272978969,1.169561852,0.884623278,1.551197754,0.435947032,DB0120210012378_,0.830234528,0.156629193,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,74434,DB01225,10012378,41,5003,21,4619,0.029777943,1.80241449,1.038963818,3.215849312,0.084226108,DB0122510012378_,2.474250332,0.58912715,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,enoxaparin,DB01225
,74441,DB00567,10013968,163,4356,74,2007,0.943366845,1.014879559,0.762292769,1.361645404,0.982230046,DB0056710013968_,0.017929735,0.014769945,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cephalexin,DB00567
,74442,DB00683,10013968,42,1542,41,1597,0.82450188,1.060937012,0.669167465,1.683112745,0.907015945,DB0068310013968_,0.097595249,0.059152492,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,midazolam,DB00683
,74443,DB00687,10013968,46,940,40,1045,0.272229701,1.278299998,0.810436502,2.023612956,0.435147026,DB0068710013968_,0.832071314,0.245531069,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fludrocortisone,DB00687
,74444,DB00878,10013968,58,1128,36,884,0.289793254,1.262469636,0.810567622,1.989409172,0.454976448,DB0087810013968_,0.787509624,0.233069831,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,chlorhexidine,DB00878
,74445,DB01190,10013968,126,4808,75,2210,0.090370756,0.772211684,0.572981553,1.046781394,0.195828138,DB0119010013968_,1.630517852,-0.258496564,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clindamycin,DB01190
,74454,DB00316,10014561,33,65441,20,36933,0.777077093,0.931213658,0.518657459,1.712685313,0.878512755,DB0031610014561_,0.129524852,-0.071266535,NA,10014561,Emphysema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,74556,DB00687,10016256,81,905,67,1018,0.073495094,1.35969553,0.958888582,1.933181345,0.167351197,DB0068710016256_,1.787660699,0.3072608,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fludrocortisone,DB00687
,74557,DB01190,10016256,173,4761,77,2208,0.835569673,1.041960721,0.788102111,1.388021252,0.914871949,DB0119010016256_,0.08897117,0.041104247,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,clindamycin,DB01190
,74558,DB01225,10016256,305,4739,207,4433,0.000541005,1.378239506,1.145785293,1.660359729,0.003294025,DB0122510016256_,5.715645105,0.320806964,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,74564,DB00188,10017885,35,7851,15,8813,0.001544005,2.619097746,1.392511007,5.165293857,0.007877146,DB0018810017885_,4.843789569,0.962829887,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,74565,DB00285,10017885,60,10891,12,3706,0.102794612,1.701271407,0.904699035,3.478547661,0.215206335,DB0028510017885_,1.536158015,0.531375858,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,74570,DB00480,10017885,187,67241,108,67554,3.66664426657028e-06,1.73952328,1.36503784,2.226031714,4.5025809178603e-05,DB0048010017885_,10.0082747,0.553611099,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,74574,DB00813,10017885,39,10533,22,10146,0.053559916,1.707542414,0.986903862,3.026041465,0.131670633,DB0081310017885_,2.027451681,0.535055152,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,74577,DB00924,10017885,71,10091,31,4220,0.828118521,0.957801119,0.618766621,1.513895929,0.909634356,DB0092410017885_,0.094712567,-0.043115123,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,74620,DB00264,10018852,70,29537,54,24838,0.652862653,1.090100767,0.753115956,1.585303871,0.787016204,DB0026410018852_,0.239506441,0.086270138,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,74626,DB00480,10018852,25,67403,31,67631,0.50435097,0.809182312,0.45804262,1.416209863,0.665390872,DB0048010018852_,0.407380634,-0.211731033,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,lenalidomide,DB00480
,74630,DB00722,10018852,39,25364,34,25998,0.55842852,1.175725702,0.722910527,1.920622966,0.711381668,DB0072210018852_,0.340546189,0.161885576,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,lisinopril,DB00722
,74634,DB00996,10018852,39,38914,31,22394,0.213814828,0.724010265,0.440062705,1.200453051,0.366009921,DB0099610018852_,1.00509484,-0.322949709,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,gabapentin,DB00996
,74637,DB01225,10018852,63,4981,87,4553,0.013416616,0.661948798,0.469662265,0.928532959,0.044987339,DB0122510018852_,3.10137418,-0.412567071,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,enoxaparin,DB01225
,74646,DB00264,10019196,88,29519,60,24832,0.216204803,1.233784888,0.878257703,1.743561274,0.368866598,DB0026410019196_,0.997320224,0.210086589,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,74647,DB00285,10019196,42,10909,12,3706,0.753868689,1.189000292,0.613759274,2.483691822,0.861598714,DB0028510019196_,0.148965646,0.173112863,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,74649,DB00316,10019196,174,65300,83,36870,0.216963324,1.183643253,0.905931075,1.557039922,0.369848631,DB0031610019196_,0.994661464,0.168597185,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,74653,DB00425,10019196,36,12659,26,7458,0.432035781,0.815759085,0.478631686,1.408145757,0.600484388,DB0042510019196_,0.510018636,-0.203636206,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,74655,DB00480,10019196,114,67314,96,67566,0.214179045,1.191942504,0.900321335,1.5808077,0.366492819,DB0048010019196_,1.003776352,0.175584333,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,74658,DB00695,10019196,117,27932,59,20469,0.021572376,1.453197779,1.053289678,2.023579008,0.065647456,DB0069510019196_,2.72345643,0.373766493,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,74659,DB00722,10019196,61,25342,42,25990,0.048602398,1.48949858,0.988774473,2.263021616,0.122440795,DB0072210019196_,2.100127673,0.39843954,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,74665,DB00996,10019196,136,38817,54,22371,0.01938073,1.451463078,1.051132487,2.029101809,0.060308095,DB0099610019196_,2.808288946,0.372572067,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,74667,DB01136,10019196,27,9857,32,11083,0.896470948,0.948683508,0.546404649,1.635838021,0.956301489,DB0113610019196_,0.044682051,-0.052680037,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,74669,DB01202,10019196,42,6672,27,5691,0.276768182,1.326806698,0.797990911,2.240898774,0.440233081,DB0120210019196_,0.820450962,0.282775077,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,levetiracetam,DB01202
,74671,DB01234,10019196,44,31581,39,32849,0.510380667,1.173499056,0.744908029,1.854993437,0.670784562,DB0123410019196_,0.399307264,0.159989931,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,74677,DB00285,10020772,115,10836,50,3668,0.149738319,0.778567127,0.552669797,1.110477966,0.283608359,DB0028510020772_,1.26016101,-0.250300065,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,venlafaxine,DB00285
,74681,DB00497,10020772,173,19094,148,16227,0.955205372,0.993403231,0.79221048,1.246958191,0.993022196,DB0049710020772_,0.007002262,-0.006618624,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,oxycodone,DB00497
,74682,DB00567,10020772,60,4459,27,2054,1,1.023661825,0.637679797,1.682584919,1,DB0056710020772_,0,0.023386223,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,cephalexin,DB00567
,74683,DB00687,10020772,45,941,34,1051,0.107419842,1.477953974,0.917113802,2.401287777,0.222298985,DB0068710020772_,1.503732023,0.390658681,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,fludrocortisone,DB00687
,74685,DB00927,10020772,87,7410,69,4947,0.286632156,0.841787303,0.605348436,1.174417743,0.451388547,DB0092710020772_,0.795426788,-0.172227906,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,famotidine,DB00927
,74686,DB01202,10020772,75,6639,64,5654,1,0.998009039,0.70396794,1.418449091,1,DB0120210020772_,0,-0.001992946,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,levetiracetam,DB01202
,74687,DB01225,10020772,46,4998,39,4601,0.744294228,1.085755447,0.691823701,1.711782463,0.853959003,DB0122510020772_,0.157872093,0.08227601,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,enoxaparin,DB01225
,74696,DB00399,10020947,53,6939,16,4982,0.001974311,2.378102313,1.336821991,4.462254452,0.009631545,DB0039910020947_,4.642711618,0.866302822,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,zoledronic acid,DB00399
,74700,DB00480,10020947,45,67383,37,67625,0.379086379,1.220580293,0.772369068,1.939579956,0.549102333,DB0048010020947_,0.599470457,0.199326396,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,74715,DB01234,10020947,61,31564,53,32835,0.349700938,1.197283658,0.814669377,1.764505701,0.519297269,DB0123410020947_,0.655278787,0.180055373,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,74722,DB00285,10021097,133,10818,65,3653,0.01698682,0.690960143,0.508551487,0.946803862,0.054358239,DB0028510021097_,2.912159092,-0.369673136,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,venlafaxine,DB00285
,74726,DB00567,10021097,50,4469,41,2040,0.006324053,0.556762844,0.359697592,0.865984957,0.024701351,DB0056710021097_,3.70089735,-0.585615903,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,cephalexin,DB00567
,74727,DB00683,10021097,94,1490,125,1513,0.058803964,0.763674348,0.572386758,1.016163454,0.141228878,DB0068310021097_,1.957373456,-0.269613826,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,midazolam,DB00683
,74728,DB00687,10021097,58,928,77,1008,0.285281961,0.81826186,0.564782968,1.180188832,0.449855201,DB0068710021097_,0.798829523,-0.200572871,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,fludrocortisone,DB00687
,74729,DB00878,10021097,37,1149,33,887,0.624299952,0.865610211,0.522011969,1.440820662,0.764167097,DB0087810021097_,0.2689688,-0.144320575,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,chlorhexidine,DB00878
,74730,DB00916,10021097,68,5255,60,2371,0.000233298,0.511376909,0.354760809,0.738764694,0.001638105,DB0091610021097_,6.414215112,-0.670648369,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,metronidazole,DB00916
,74731,DB00927,10021097,177,7320,134,4882,0.291634707,0.880969325,0.69774775,1.114431544,0.457103057,DB0092710021097_,0.782846406,-0.126732472,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,famotidine,DB00927
,74732,DB01190,10021097,54,4880,47,2238,0.00168851,0.526937335,0.348586897,0.799109746,0.008461816,DB0119010021097_,4.772191529,-0.640673646,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,clindamycin,DB01190
,74733,DB01327,10021097,34,629,50,707,0.260552832,0.764469072,0.47282781,1.223193988,0.422018608,DB0132710021097_,0.86270587,-0.268573709,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,cefazolin,DB01327
,74739,DB00316,10021143,334,65140,277,36676,2.57221126673537e-06,0.678924175,0.576884008,0.79944416,3.30210369456113e-05,DB0031610021143_,10.31836572,-0.387245829,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,74740,DB00319,10021143,32,1360,42,1811,1,1.014564458,0.616370412,1.655790662,1,DB0031910021143_,0,0.014459415,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,piperacillin,DB00319
,74743,DB00425,10021143,49,12646,36,7448,0.313453018,0.801661947,0.510282752,1.270225971,0.480975632,DB0042510021143_,0.73193867,-0.221068272,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,74746,DB00683,10021143,40,1544,49,1589,0.452551001,0.840164716,0.535783159,1.31062976,0.620176901,DB0068310021143_,0.477750517,-0.174157316,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,midazolam,DB00683
,74748,DB00722,10021143,76,25327,116,25916,0.00732151,0.6704173,0.49500112,0.90350278,0.027743946,DB0072210021143_,3.584737619,-0.399854924,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,74749,DB00813,10021143,101,10471,89,10079,0.560428433,1.092318535,0.812182645,1.471260658,0.713082649,DB0081310021143_,0.338157947,0.088302534,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,74753,DB01202,10021143,44,6670,50,5668,0.177051341,0.747824691,0.486333119,1.146279839,0.320101419,DB0120210021143_,1.139117398,-0.290586699,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levetiracetam,DB01202
,74754,DB01225,10021143,67,4977,76,4564,0.237694043,0.808444071,0.571772232,1.140863703,0.395151498,DB0122510021143_,0.928486047,-0.212643779,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enoxaparin,DB01225
,74755,DB01275,10021143,46,3933,18,3331,0.005201614,2.164126495,1.228000452,3.973342774,0.021120633,DB0127510021143_,3.857504835,0.772016814,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydralazine,DB01275
,74761,DB00285,10021789,62,10889,18,3700,0.608398597,1.170380623,0.682333385,2.105225583,0.751034851,DB0028510021789_,0.286303222,0.157329015,NA,10021789,Infection,10021881,Infections and infestations,Infec,venlafaxine,DB00285
,74767,DB00813,10021789,62,10510,41,10127,0.074838354,1.457056301,0.965485993,2.219869348,0.169572531,DB0081310021789_,1.774474532,0.376418168,NA,10021789,Infection,10021881,Infections and infestations,Infec,fentanyl,DB00813
,74769,DB00916,10021789,70,5253,26,2405,0.438372339,1.232572273,0.773431416,2.020264279,0.606790786,DB0091610021789_,0.499571217,0.209103265,NA,10021789,Infection,10021881,Infections and infestations,Infec,metronidazole,DB00916
,74770,DB00927,10021789,91,7406,37,4979,0.010855489,1.653411499,1.114600303,2.497566707,0.038019524,DB0092710021789_,3.269655475,0.502840728,NA,10021789,Infection,10021881,Infections and infestations,Infec,famotidine,DB00927
,74771,DB01136,10021789,88,9796,91,11024,0.598974724,1.088247276,0.801429965,1.477143874,0.743713444,DB0113610021789_,0.296099475,0.084568399,NA,10021789,Infection,10021881,Infections and infestations,Infec,carvedilol,DB01136
,74772,DB01190,10021789,50,4884,22,2263,0.899220671,1.053059611,0.624290008,1.830803688,0.956490275,DB0119010021789_,0.044484657,0.051699842,NA,10021789,Infection,10021881,Infections and infestations,Infec,clindamycin,DB01190
,74773,DB01225,10021789,55,4989,44,4596,0.54434757,1.151516026,0.758899576,1.756309275,0.699375608,DB0122510021789_,0.357567331,0.141079358,NA,10021789,Infection,10021881,Infections and infestations,Infec,enoxaparin,DB01225
,74774,DB01275,10021789,24,3955,38,3311,0.014805058,0.528790318,0.302764645,0.906762839,0.048811658,DB0127510021789_,3.019786106,-0.637163301,NA,10021789,Infection,10021881,Infections and infestations,Infec,hydralazine,DB01275
,74785,DB00996,10022116,90,38863,38,22387,0.118290694,1.36432031,0.923678957,2.050266802,0.238669806,DB0099610022116_,1.432674246,0.310656363,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,74860,DB00188,10024855,34,7852,63,8765,0.018631565,0.602454689,0.384396269,0.92958605,0.05843693,DB0018810024855_,2.83980723,-0.506742821,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,74865,DB00567,10024855,38,4481,16,2065,0.883288324,1.094465309,0.594279408,2.107575054,0.951194608,DB0056710024855_,0.050036602,0.090265942,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,cephalexin,DB00567
,74866,DB00687,10024855,44,942,37,1048,0.256365014,1.322818244,0.826890021,2.126465658,0.41718337,DB0068710024855_,0.874229417,0.279764494,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,fludrocortisone,DB00687
,74869,DB00927,10024855,51,7446,23,4993,0.122683145,1.486850977,0.890990705,2.552628118,0.24526365,DB0092710024855_,1.405421524,0.396660445,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,74871,DB01136,10024855,81,9803,82,11033,0.528926353,1.111740227,0.806578021,1.53211367,0.686237527,DB0113610024855_,0.376531462,0.10592656,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,74873,DB01202,10024855,51,6663,45,5673,0.91822141,0.964930428,0.632441595,1.476706251,0.963779565,DB0120210024855_,0.036892678,-0.035699276,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,74875,DB01234,10024855,141,31484,173,32715,0.157107373,0.84689889,0.672816845,1.064585546,0.29361636,DB0123410024855_,1.225481261,-0.166173966,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,74876,DB01275,10024855,31,3948,27,3322,0.895654618,0.966088255,0.55669409,1.686138337,0.95615204,DB0127510024855_,0.044838341,-0.034500088,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,hydralazine,DB01275
,74918,DB00264,10025197,55,29552,40,24852,0.536684578,1.156314172,0.755307151,1.78416649,0.692968223,DB0026410025197_,0.366771135,0.145237508,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,metoprolol,DB00264
,74933,DB00996,10025197,50,38903,21,22404,0.267075199,1.371169047,0.808443143,2.404043425,0.429349048,DB0099610025197_,0.84548506,0.315663695,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,gabapentin,DB00996
,74938,DB01234,10025197,62,31563,46,32842,0.083595625,1.402428481,0.94203245,2.101310983,0.184435985,DB0123410025197_,1.690452842,0.338205363,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,dexamethasone,DB01234
,75111,DB00012,10029331,40,1606,18,1295,0.044830677,1.791552621,0.998119159,3.336774206,0.115255708,DB0001210029331_,2.160602075,0.58308263,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,darbepoetin alfa,DB00012
,75114,DB00567,10029331,56,4463,27,2054,0.813399144,0.954555373,0.590940267,1.576772635,0.899775248,DB0056710029331_,0.105610271,-0.046509625,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,cephalexin,DB00567
,75117,DB00813,10029331,93,10479,59,10109,0.011598061,1.520577642,1.0843454,2.146948841,0.040080863,DB0081310029331_,3.216856291,0.41909029,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,75119,DB00927,10029331,104,7393,57,4959,0.257095522,1.223825866,0.875779837,1.725155685,0.417971041,DB0092710029331_,0.872343129,0.201981908,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,75120,DB01202,10029331,25,6689,33,5685,0.112660645,0.64389588,0.36660769,1.1177673,0.23008314,DB0120210029331_,1.469314558,-0.440218243,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,75121,DB01275,10029331,44,3935,31,3318,0.485594845,1.196773047,0.7369783,1.965231432,0.649625274,DB0127510029331_,0.431359584,0.179628807,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,hydralazine,DB01275
,75130,DB00497,10031161,42,19225,32,16343,0.726411884,1.115716341,0.687386876,1.826999511,0.839857326,DB0049710031161_,0.174523252,0.109496657,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,75134,DB00695,10031161,110,27939,38,20490,3.77321954402517e-05,2.122903338,1.455240609,3.157465225,0.000347205,DB0069510031161_,7.965595502,0.752784651,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,75257,DB00012,10033371,89,1557,55,1258,0.143643505,1.307314429,0.915597966,1.880477712,0.275024185,DB0001210033371_,1.290896239,0.267974978,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,darbepoetin alfa,DB00012
,75260,DB00878,10033371,43,1143,25,895,0.264813414,1.346618772,0.797158059,2.319614131,0.426757033,DB0087810033371_,0.851540437,0.297596837,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,chlorhexidine,DB00878
,75261,DB01202,10033371,143,6571,79,5639,0.00173185,1.553328473,1.169142703,2.076305876,0.008635432,DB0120210033371_,4.751881596,0.440400031,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,75262,DB01275,10033371,95,3884,50,3299,0.006881572,1.613719157,1.130212583,2.328154996,0.026444755,DB0127510033371_,3.632697424,0.47854155,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,75267,DB00285,10033775,136,10815,37,3681,0.253301779,1.251027124,0.862399964,1.855186134,0.41377399,DB0028510033775_,0.882435373,0.223964913,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,75270,DB00425,10033775,198,12497,60,7424,1.93091395621153e-06,1.960344389,1.459442256,2.666461905,2.56852597869535e-05,DB0042510033775_,10.56959328,0.673120167,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,75272,DB00497,10033775,150,19117,98,16277,0.04727335,1.303214775,1.002715692,1.700193716,0.119969105,DB0049710033775_,2.120521028,0.264834116,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,75273,DB00567,10033775,42,4477,10,2071,0.070837147,1.942693813,0.956821445,4.350975241,0.162779595,DB0056710033775_,1.815358169,0.664075573,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,cephalexin,DB00567
,75277,DB00927,10033775,92,7405,31,4985,0.000588078,1.997756452,1.314476642,3.111407175,0.003536001,DB0092710033775_,5.644758864,0.692024777,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,75278,DB01202,10033775,39,6675,27,5691,0.458214802,1.231489082,0.733876502,2.094750478,0.625590239,DB0120210033775_,0.469059692,0.208224073,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,75279,DB01225,10033775,44,5000,24,4616,0.038586611,1.692436728,1.005077829,2.914829691,0.102802933,DB0122510033775_,2.274941398,0.526169341,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,enoxaparin,DB01225
,75280,DB01275,10033775,37,3942,13,3336,0.006230735,2.408277386,1.248672777,4.946172441,0.024391222,DB0127510033775_,3.71353198,0.878911714,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,hydralazine,DB01275
,75330,DB00927,10035226,64,7433,60,4956,0.065285396,0.711241555,0.491233743,1.030900113,0.152929921,DB0092710035226_,1.877775495,-0.340743167,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,famotidine,DB00927
,75333,DB01225,10035226,45,4999,66,4574,0.016608381,0.623887804,0.416400736,0.927295093,0.053381181,DB0122510035226_,2.930297002,-0.471784727,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,enoxaparin,DB01225
,75334,DB01275,10035226,27,3952,41,3308,0.019525049,0.551276443,0.325373744,0.9201948,0.060678164,DB0127510035226_,2.802171379,-0.595518884,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,hydralazine,DB01275
,75368,DB01234,10035484,73,31552,86,32802,0.47489207,0.882467848,0.63675,1.220221045,0.640524326,DB0123410035484_,0.445468178,-0.125032924,NA,10035484,Plasmacytoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,75380,DB00813,10035598,59,10513,26,10142,0.000678726,2.188946713,1.357116979,3.621452303,0.00399194,DB0081310035598_,5.523478039,0.783420475,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,75384,DB01202,10035598,30,6684,23,5695,0.782913309,1.111313376,0.623378689,2.005963978,0.881806742,DB0120210035598_,0.12578236,0.105542537,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levetiracetam,DB01202
,75385,DB01275,10035598,53,3926,41,3308,0.754810346,1.089218947,0.708880352,1.684076708,0.862329068,DB0127510035598_,0.148118331,0.085460877,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydralazine,DB01275
,75390,DB00012,10035664,41,1605,55,1258,0.011869988,0.584405331,0.377537733,0.898359834,0.040822012,DB0001210035664_,3.198533838,-0.537160478,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,darbepoetin alfa,DB00012
,75394,DB00567,10035664,138,4381,67,2014,0.703392553,0.946878969,0.698612667,1.293824484,0.822102459,DB0056710035664_,0.195890246,-0.054583999,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cephalexin,DB00567
,75395,DB00683,10035664,29,1555,35,1603,0.613842077,0.854190371,0.501010021,1.446315928,0.755464777,DB0068310035664_,0.28042212,-0.157601193,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,midazolam,DB00683
,75396,DB00878,10035664,53,1133,43,877,0.83381923,0.954056752,0.619538184,1.476340879,0.913682907,DB0087810035664_,0.090271697,-0.047032121,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,chlorhexidine,DB00878
,75397,DB00927,10035664,303,7194,234,4782,0.095880141,0.860742007,0.720414665,1.029381797,0.204608474,DB0092710035664_,1.586657009,-0.149960463,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,famotidine,DB00927
,75398,DB01190,10035664,82,4852,62,2223,0.003700704,0.605995657,0.428687726,0.86037589,0.016023887,DB0119010035664_,4.13367475,-0.50088246,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,clindamycin,DB01190
,75409,DB00497,10037423,84,19183,74,16301,0.872953772,0.964583274,0.696760671,1.337736806,0.944569365,DB0049710037423_,0.057026154,-0.036059111,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,75412,DB00722,10037423,100,25303,131,25901,0.064976293,0.781405211,0.595864138,1.022131972,0.152402789,DB0072210037423_,1.881228333,-0.246661428,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,75413,DB00813,10037423,72,10500,96,10072,0.036436055,0.719443541,0.521850491,0.988109807,0.098444952,DB0081310037423_,2.318257751,-0.329277226,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,75417,DB00927,10037423,53,7444,29,4987,0.429387251,1.224328263,0.763251658,2.000017754,0.597877421,DB0092710037423_,0.514369528,0.202392337,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,75418,DB00996,10037423,130,38823,89,22336,0.206526536,0.840378468,0.636494897,1.113799554,0.357101823,DB0099610037423_,1.02973432,-0.173902931,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,75421,DB01225,10037423,32,5012,21,4619,0.27018926,1.404272128,0.783863097,2.566352888,0.432846057,DB0122510037423_,0.837373141,0.33951911,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enoxaparin,DB01225
,75422,DB01234,10037423,114,31511,112,32776,0.689529824,1.058743642,0.808087563,1.387275036,0.812875364,DB0123410037423_,0.207177486,0.057082962,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,75423,DB01275,10037423,51,3928,63,3286,0.046207068,0.677257297,0.457390447,0.998626126,0.117894855,DB0127510037423_,2.137962114,-0.389704024,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydralazine,DB01275
,75465,DB00319,10038695,60,1332,81,1772,1,0.985433482,0.688213914,1.404460254,1,DB0031910038695_,0,-0.014673651,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,piperacillin,DB00319
,75467,DB00497,10038695,159,19108,159,16216,0.157598641,0.848655516,0.676177999,1.06515903,0.294273148,DB0049710038695_,1.223246869,-0.164101927,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,75471,DB00916,10038695,42,5281,35,2396,0.009292304,0.544459727,0.33842857,0.880896426,0.033557493,DB0091610038695_,3.394495092,-0.607961302,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metronidazole,DB00916
,75472,DB00924,10038695,45,10117,16,4235,0.673492516,1.177297808,0.651931217,2.234000243,0.801972944,DB0092410038695_,0.220680407,0.163221819,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,75474,DB01225,10038695,78,4966,107,4533,0.007337187,0.66544415,0.489105261,0.901973303,0.027793335,DB0122510038695_,3.582959052,-0.407300567,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enoxaparin,DB01225
,75479,DB00188,10039117,22,7864,33,8795,0.343836784,0.745606212,0.413759263,1.319097534,0.513085802,DB0018810039117_,0.667312192,-0.293557684,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,bortezomib,DB00188
,75480,DB00264,10039117,56,29551,55,24837,0.445841956,0.855764722,0.578977436,1.265322752,0.613686416,DB0026410039117_,0.488271204,-0.155759798,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,75484,DB00399,10039117,34,6958,27,4971,0.697616603,0.899661082,0.526133396,1.552423636,0.81818943,DB0039910039117_,0.200661392,-0.105737163,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,zoledronic acid,DB00399
,75490,DB00722,10039117,34,25369,40,25992,0.56327107,0.87087681,0.53452432,1.411580556,0.71530937,DB0072210039117_,0.335040144,-0.138254748,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,75508,DB00567,10040047,47,4472,43,2038,0.001273186,0.498159008,0.321213435,0.77440277,0.006709916,DB0056710040047_,5.004168871,-0.69683596,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,cephalexin,DB00567
,75509,DB00683,10040047,31,1553,39,1599,0.468717802,0.818467953,0.491021301,1.353809951,0.635136587,DB0068310040047_,0.453915206,-0.200321036,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,midazolam,DB00683
,75510,DB00813,10040047,125,10447,98,10070,0.13841148,1.229466836,0.934817064,1.620818198,0.267540225,DB0081310040047_,1.31848535,0.206580609,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,fentanyl,DB00813
,75511,DB00878,10040047,42,1144,28,892,0.543024397,1.1694936,0.701782575,1.97582906,0.698204582,DB0087810040047_,0.359243121,0.156570835,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,chlorhexidine,DB00878
,75512,DB00924,10040047,85,10077,60,4191,0.002396147,0.589211988,0.417587132,0.835915237,0.011275829,DB0092410040047_,4.485093875,-0.528969249,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,cyclobenzaprine,DB00924
,75513,DB01041,10040047,25,3020,55,3063,0.001041298,0.461074892,0.274521822,0.754767763,0.005698454,DB0104110040047_,5.167560334,-0.774194795,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,thalidomide,DB01041
,75514,DB01202,10040047,55,6659,65,5653,0.080136189,0.718347388,0.491411269,1.046809586,0.178627861,DB0120210040047_,1.722450628,-0.330802,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,levetiracetam,DB01202
,75521,DB00264,10040943,48,29559,50,24842,0.310683897,0.806810382,0.531243504,1.224064996,0.47808016,DB0026410040943_,0.737976863,-0.214666605,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,75529,DB00480,10040943,91,67337,101,67561,0.515931993,0.903993871,0.673252225,1.212360762,0.675631348,DB0048010040943_,0.392107694,-0.100932699,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,75530,DB00497,10040943,44,19223,34,16341,0.73347991,1.100060701,0.686925338,1.775683449,0.845407561,DB0049710040943_,0.167936447,0.095365361,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,75534,DB00695,10040943,77,27972,68,20460,0.27404904,0.828262105,0.589626278,1.165698952,0.43714911,DB0069510040943_,0.827480929,-0.188425623,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,75539,DB00996,10040943,75,38878,44,22381,0.924291261,0.981251764,0.667218727,1.458465689,0.967272995,DB0099610040943_,0.033274512,-0.018926212,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,75545,DB01234,10040943,54,31571,52,32836,0.698645724,1.080044072,0.723947369,1.612572256,0.818811854,DB0123410040943_,0.199900948,0.077001847,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,75554,DB00567,10041349,34,4485,17,2064,0.764037533,0.920415484,0.498766957,1.761053677,0.869551495,DB0056710041349_,0.139777724,-0.082930097,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,cephalexin,DB00567
,75558,DB00916,10041349,33,5290,17,2414,0.759850842,0.885842945,0.47835089,1.699250276,0.866380922,DB0091610041349_,0.143430604,-0.121215607,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,metronidazole,DB00916
,75559,DB00924,10041349,161,10001,50,4201,0.067812296,1.35250994,0.977003794,1.900931873,0.157404293,DB0092410041349_,1.848937672,0.301962081,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,75560,DB00927,10041349,95,7402,42,4974,0.028050454,1.519906239,1.044423736,2.24481735,0.080338456,DB0092710041349_,2.521506868,0.418648648,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,75561,DB01136,10041349,103,9781,83,11032,0.026618505,1.39965199,1.036647714,1.894552021,0.077136585,DB0113610041349_,2.562177601,0.336223627,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,75562,DB01225,10041349,31,5013,24,4616,0.589032139,1.189352072,0.674508955,2.121250534,0.735835263,DB0122510041349_,0.306749012,0.173408682,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,enoxaparin,DB01225
,75563,DB01275,10041349,44,3935,33,3316,0.646873061,1.123554043,0.697487321,1.825986407,0.782237168,DB0127510041349_,0.2455973,0.116496914,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,hydralazine,DB01275
,75568,DB00285,10042772,54,10897,32,3686,0.017377671,0.57083742,0.361366199,0.915058264,0.05534954,DB0028510042772_,2.894086923,-0.560650838,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,75571,DB00425,10042772,94,12601,61,7423,0.559894775,0.907769184,0.649859725,1.276041844,0.712558848,DB0042510042772_,0.338892776,-0.096765136,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,75575,DB00687,10042772,52,934,42,1043,0.139136263,1.382357532,0.893517214,2.149540829,0.268595525,DB0068710042772_,1.314548657,0.323790398,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,fludrocortisone,DB00687
,75578,DB00924,10042772,43,10119,30,4221,0.038581248,0.597918441,0.365922761,0.988582365,0.102802933,DB0092410042772_,2.274941398,-0.51430092,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,75579,DB00927,10042772,70,7427,50,4966,0.77900952,0.936103435,0.64070428,1.376454548,0.879583549,DB0092710042772_,0.128306723,-0.066029301,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,75581,DB01225,10042772,45,4999,37,4603,0.657721565,1.119851582,0.707297809,1.78289295,0.790788187,DB0122510042772_,0.234725126,0.11319616,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,enoxaparin,DB01225
,75629,DB00916,10043554,41,5282,29,2402,0.07097875,0.642961226,0.38894393,1.075556613,0.163012358,DB0091610043554_,1.813929267,-0.441670859,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,metronidazole,DB00916
,75630,DB00924,10043554,33,10129,21,4230,0.135977725,0.656269446,0.36806022,1.195122587,0.264049534,DB0092410043554_,1.331618564,-0.421183833,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,cyclobenzaprine,DB00924
,75632,DB01275,10043554,24,3955,33,3316,0.081844843,0.609818076,0.34412754,1.065951709,0.181459381,DB0127510043554_,1.706723448,-0.494594602,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,hydralazine,DB01275
,75676,DB00316,10044044,37,65437,18,36935,0.674785932,1.160209984,0.643930255,2.1651814,0.802790166,DB0031610044044_,0.219661912,0.148601009,NA,10044044,Tooth loss,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,75717,DB00695,10044640,51,27998,22,20506,0.043160818,1.697835063,1.010988365,2.940987385,0.111981256,DB0069510044640_,2.18942378,0.529353947,NA,10044640,Tricuspid valve incompetence,10007541,Cardiac disorders,Card,furosemide,DB00695
,75739,DB00567,10046571,186,4333,52,2029,0.000824191,1.674835587,1.21943191,2.334571595,0.004693211,DB0056710046571_,5.361638192,0.515715003,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,cephalexin,DB00567
,75742,DB01275,10046571,103,3876,27,3322,3.6313047649184e-09,3.268935259,2.116459291,5.210321651,8.97919527242522e-08,DB0127510046571_,16.22577048,1.184464323,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,hydralazine,DB01275
,75756,DB00927,10048294,41,7456,34,4982,0.347756319,0.805776096,0.498142578,1.311035398,0.517319384,DB0092710048294_,0.659094832,-0.215949371,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,famotidine,DB00927
,75758,DB01136,10048294,78,9806,60,11055,0.026259453,1.465543419,1.032088615,2.08992612,0.076340177,DB0113610048294_,2.572555908,0.382226108,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,carvedilol,DB01136
,75760,DB01225,10048294,41,5003,47,4593,0.335013315,0.800872207,0.512638786,1.246691664,0.50419564,DB0122510048294_,0.684790912,-0.222053887,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,enoxaparin,DB01225
,75761,DB01234,10048294,111,31514,146,32742,0.069636572,0.789903876,0.611175282,1.018507775,0.16064913,DB0123410048294_,1.828532611,-0.235844017,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,75762,DB01275,10048294,47,3932,35,3314,0.655977266,1.131764354,0.713333627,1.810954831,0.789575842,DB0127510048294_,0.236259387,0.12377779,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,hydralazine,DB01275
,75804,DB00188,10048959,182,7704,154,8674,0.011008684,1.330588936,1.06525281,1.663827679,0.038422952,DB0018810048959_,3.259100287,0.285621653,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,75805,DB00285,10048959,150,10801,49,3669,0.869809216,1.039893351,0.746803214,1.469943042,0.942090076,DB0028510048959_,0.059654387,0.039118161,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,75810,DB00480,10048959,1346,66082,980,66682,1.04558772243739e-14,1.385930458,1.274570191,1.507449439,6.12099627711955e-13,DB0048010048959_,28.12188134,0.326371725,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,75811,DB00567,10048959,76,4443,32,2049,0.754242766,1.095273068,0.71314714,1.717143869,0.861874627,DB0056710048959_,0.148645463,0.091003709,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,75814,DB00722,10048959,457,24946,346,25686,1.90477519302343e-05,1.359975736,1.178790371,1.570191092,0.000191351,DB0072210048959_,8.561400585,0.307466859,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,75815,DB00813,10048959,115,10457,52,10116,3.62290942193089e-06,2.139336479,1.527085466,3.032185272,4.46033602601656e-05,DB0081310048959_,10.01770136,0.760495724,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,75817,DB00916,10048959,49,5274,13,2418,0.098001386,1.727991372,0.921035067,3.478785461,0.207881729,DB0091610048959_,1.570785972,0.546959677,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,75818,DB00924,10048959,212,9950,63,4188,0.016087993,1.416391573,1.061754915,1.912056462,0.052042692,DB0092410048959_,2.955690905,0.348112492,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,75819,DB00927,10048959,161,7336,73,4943,0.005655243,1.486006869,1.117352953,1.992160532,0.022580594,DB0092710048959_,3.790664421,0.396092569,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,75820,DB01041,10048959,59,2986,44,3074,0.112486098,1.380348491,0.915210559,2.095618903,0.22981549,DB0104110048959_,1.47047851,0.322335997,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,thalidomide,DB01041
,75821,DB01202,10048959,47,6667,39,5679,0.914105806,1.026538414,0.656064133,1.614344884,0.961536643,DB0120210048959_,0.039222604,0.026192379,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,75822,DB01225,10048959,80,4964,46,4594,0.011691175,1.609417236,1.103526488,2.371656777,0.040321222,DB0122510048959_,3.210877344,0.475872148,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,75823,DB01234,10048959,678,30947,507,32381,1.20502087924807e-08,1.399229098,1.243940781,1.57469282,2.66391705727801e-07,DB0123410048959_,15.13829803,0.335921441,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,75824,DB01275,10048959,82,3897,51,3298,0.095030457,1.36064611,0.94461627,1.976016483,0.203269363,DB0127510048959_,1.593223267,0.307959668,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,75838,DB00924,10049119,43,10119,10,4241,0.097711703,1.802119676,0.890696871,4.025316337,0.207442122,DB0092410049119_,1.57290291,0.58896357,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,75884,DB00497,10050296,53,19214,32,16343,0.128564071,1.408753109,0.891242163,2.259153879,0.253589747,DB0049710050296_,1.372037487,0.342704993,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,75890,DB00924,10050296,46,10116,10,4241,0.056960436,1.928414074,0.958787049,4.289889498,0.137724687,DB0092410050296_,1.982498608,0.656697942,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,75899,DB00285,10051055,37,10914,17,3701,0.346104607,0.738070196,0.404771278,1.399571634,0.515533369,DB0028510051055_,0.662553246,-0.303716343,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,venlafaxine,DB00285
,75906,DB00927,10051055,63,7434,57,4959,0.111236012,0.737319534,0.506066872,1.076220331,0.227908532,DB0092710051055_,1.478810904,-0.30473392,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,famotidine,DB00927
,75907,DB01041,10051055,39,3006,56,3062,0.120471834,0.709444729,0.457444721,1.090570904,0.242039452,DB0104110051055_,1.418654543,-0.343272686,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,thalidomide,DB01041
,75908,DB01202,10051055,29,6685,44,5674,0.017932305,0.559446913,0.33708246,0.915726401,0.056707246,DB0120210051055_,2.869853278,-0.580806639,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,levetiracetam,DB01202
,75954,DB00399,10052904,57,6935,14,4984,0.000142267,2.925753367,1.607423957,5.692153706,0.001078125,DB0039910052904_,6.832531573,1.073552009,female,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,75957,DB00480,10052904,221,67207,181,67481,0.045608308,1.225968386,1.002408842,1.501009977,0.116741102,DB0048010052904_,2.147796596,0.203731051,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,75958,DB00497,10052904,80,19187,53,16322,0.163967336,1.284034971,0.895634049,1.854007266,0.302734621,DB0049710052904_,1.194898695,0.250007441,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,75960,DB00682,10052904,42,19417,40,16324,0.580873433,0.882746009,0.558413403,1.397322795,0.729334743,DB0068210052904_,0.315622471,-0.124717765,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,75963,DB00695,10052904,137,27912,70,20458,0.013587654,1.434468946,1.067246849,1.942715421,0.045453578,DB0069510052904_,3.091063746,0.360794709,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,75964,DB00813,10052904,44,10528,22,10146,0.013098085,1.927363239,1.129715014,3.379144313,0.044153163,DB0081310052904_,3.120090702,0.656152871,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,fentanyl,DB00813
,75967,DB00924,10052904,94,10068,22,4229,0.013713148,1.794668395,1.117047129,3.003795717,0.045788883,DB0092410052904_,3.083713942,0.584820267,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,75974,DB01234,10052904,113,31512,82,32806,0.014530659,1.434620679,1.069577276,1.931265481,0.048057674,DB0123410052904_,3.035353451,0.360900479,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,76017,DB00188,10054236,37,7849,36,8792,0.559100178,1.151246648,0.706902771,1.876526639,0.711840552,DB0018810054236_,0.339901337,0.140845397,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,bortezomib,DB00188
,76020,DB00319,10054236,31,1361,20,1833,0.010229013,2.087091659,1.146661588,3.882001274,0.036210142,DB0031910054236_,3.318416023,0.735771546,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,piperacillin,DB00319
,76024,DB00480,10054236,272,67156,200,67462,0.000882171,1.366188457,1.133672033,1.648639554,0.004969008,DB0048010054236_,5.304535053,0.312024715,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,76028,DB00722,10054236,66,25337,44,25988,0.027988904,1.538518161,1.034494967,2.308134535,0.080201499,DB0072210054236_,2.523213073,0.43081972,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,lisinopril,DB00722
,76031,DB00916,10054236,111,5212,48,2383,0.795916121,1.057299559,0.744337399,1.521472745,0.889464732,DB0091610054236_,0.117135422,0.055718072,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,metronidazole,DB00916
,76035,DB01234,10054236,117,31508,118,32770,0.84463646,1.031246641,0.791269059,1.343912916,0.92150127,DB0123410054236_,0.081751124,0.030768402,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,76042,DB00264,10060945,36,29571,19,24873,0.10517538,1.593699059,0.889979653,2.942165113,0.218825731,DB0026410060945_,1.519479614,0.466057767,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,76048,DB00480,10060945,48,67380,62,67600,0.214865402,0.776724819,0.521430976,1.150912978,0.367248892,DB0048010060945_,1.001715482,-0.25266915,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,76050,DB00682,10060945,44,19415,13,16351,0.000455557,2.850260214,1.507163866,5.769606999,0.002857052,DB0068210060945_,5.857964799,1.047410293,female,10060945,Bacterial infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,76057,DB00996,10060945,41,38912,13,22412,0.065595562,1.816491316,0.953946113,3.695526305,0.153486514,DB0099610060945_,1.874142576,0.596906792,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,76074,DB00497,10061246,31,19236,31,16344,0.526723079,0.849662542,0.499267118,1.445895888,0.684460073,DB0049710061246_,0.379124967,-0.162916018,NA,10061246,Intervertebral disc degeneration,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,76079,DB00722,10061246,33,25370,17,26015,0.022825034,1.990490018,1.076996151,3.81124095,0.06848813,DB0072210061246_,2.681094829,0.688380849,NA,10061246,Intervertebral disc degeneration,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,76084,DB00996,10061246,61,38892,34,22391,0.915489821,1.032914995,0.668042616,1.621302523,0.962143444,DB0099610061246_,0.03859173,0.032384897,NA,10061246,Intervertebral disc degeneration,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,76189,DB00316,10062190,46,65428,36,36917,0.166925468,0.720998456,0.45593354,1.148172161,0.306731163,DB0031610062190_,1.181783604,-0.327118283,NA,10062190,Metabolic encephalopathy,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,76207,DB00996,10062190,30,38923,22,22403,0.39042238,0.784889275,0.437712277,1.428350271,0.560273647,DB0099610062190_,0.579329959,-0.242212622,NA,10062190,Metabolic encephalopathy,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,76412,DB00181,10023547,89,9767,34,5837,0.024904474,1.564327974,1.041223464,2.399238808,0.073271855,DB0018110023547_,2.613578715,0.447456322,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,baclofen,DB00181
,76413,DB00181,10035528,32,9824,29,5842,0.111390586,0.656227412,0.384042848,1.125544565,0.228136322,DB0018110035528_,1.477811926,-0.421247886,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,baclofen,DB00181
,76414,DB00181,10048959,113,9743,55,5816,0.229623547,1.226389348,0.879435366,1.728039798,0.385480118,DB0018110048959_,0.953265663,0.204074363,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,76419,DB00008,10012735,71,1454,42,1634,0.001064561,1.89935433,1.269956935,2.871407972,0.005798773,DB0000810012735_,5.150108863,0.641514002,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,peginterferon alfa-2a,DB00008
,76432,DB00695,10073508,24,28025,33,20495,0.021803333,0.531880998,0.300701386,0.92791447,0.06617137,DB0069510073508_,2.715507387,-0.631335502,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,76433,DB00476,10001949,144,17113,35,6142,0.040662296,1.476580001,1.013317613,2.204788805,0.106961065,DB0047610001949_,2.235290389,0.389728603,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,76435,DB00996,10001949,185,38768,87,22338,0.1297987,1.225285849,0.94411359,1.600437429,0.25537117,DB0099610001949_,1.365037222,0.203174163,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,76436,DB01050,10001949,74,18034,40,9331,0.843265653,0.957222087,0.642458289,1.444807561,0.920520389,DB0105010001949_,0.082816128,-0.043719849,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,76437,DB01156,10001949,72,13550,28,6300,0.452709674,1.195545659,0.762004743,1.923900118,0.620345423,DB0115610001949_,0.477478822,0.178602699,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,76441,DB00575,10013573,141,5103,98,3731,0.740179904,1.051946969,0.804199648,1.380520445,0.850723836,DB0057510013573_,0.16166772,0.050642703,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,76443,DB00472,10020751,93,10666,27,4285,0.155580897,1.383708209,0.891746367,2.213429862,0.291561662,DB0047210020751_,1.232503762,0.324767003,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,fluoxetine,DB00472
,76444,DB00575,10020751,44,5200,19,3810,0.055213861,1.696662027,0.968377979,3.08241308,0.134709828,DB0057510020751_,2.004632236,0.528662807,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,clonidine,DB00575
,76459,DB01050,10042209,106,18002,20,9351,7.1453060863071e-06,2.752955914,1.694794336,4.692018639,8.08673285160741e-05,DB0105010042209_,9.422700666,1.012675212,female,10042209,Stress,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,76460,DB01156,10042209,91,13531,19,6309,0.000913575,2.233076652,1.349894975,3.881855216,0.005115749,DB0115610042209_,5.275431399,0.803380299,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,76463,DB00575,10044565,86,5158,49,3780,0.187696383,1.286177068,0.892900255,1.870789371,0.333689512,DB0057510044565_,1.097544324,0.251674305,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,76467,DB00019,10001760,62,18950,22,9507,0.201989051,1.413833663,0.856312417,2.416983947,0.351387022,DB0001910001760_,1.045867037,0.346304925,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,pegfilgrastim,DB00019
,76468,DB00188,10001760,66,7820,15,8813,3.24712094463702e-10,4.957857509,2.797075106,9.364422191,9.81605221734148e-09,DB0018810001760_,18.43924681,1.600973694,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,bortezomib,DB00188
,76471,DB00433,10001760,114,7542,30,5990,5.49654658080966e-09,3.017720787,2.000311879,4.68241512,1.30807357968838e-07,DB0043310001760_,15.84954015,1.10450184,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,prochlorperazine,DB00433
,76472,DB00437,10001760,69,6852,28,11518,2.22466369643231e-11,4.142025175,2.631273537,6.682799883,8.03231940394549e-10,DB0043710001760_,20.9423776,1.421184841,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,76475,DB01175,10001760,131,10593,16,4876,5.89469337060859e-09,3.768135076,2.232632949,6.796078284,1.39524552225526e-07,DB0117510001760_,15.78502525,1.326580204,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,escitalopram,DB01175
,76476,DB00227,10002034,46,2421,24,1779,0.182046487,1.408294819,0.838382767,2.421870558,0.326449169,DB0022710002034_,1.119481027,0.342379624,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,lovastatin,DB00227
,76477,DB00697,10002034,58,6038,17,1789,1,1.010872408,0.578714169,1.856605621,1,DB0069710002034_,0,0.010813728,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,tizanidine,DB00697
,76479,DB01175,10002034,145,10579,62,4830,0.706435164,1.067767425,0.786158882,1.464878728,0.824247527,DB0117510002034_,0.193284398,0.06556995,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,escitalopram,DB01175
,76480,DB00697,10003988,203,5893,57,1749,0.764115689,1.056967376,0.780215275,1.45129629,0.869621618,DB0069710003988_,0.139697084,0.055403841,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tizanidine,DB00697
,76481,DB01175,10003988,218,10506,46,4846,2.97658771795537e-07,2.185879248,1.581074947,3.079111917,4.85809426677783e-06,DB0117510003988_,12.23486432,0.782018149,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,76488,DB00531,10003997,63,7189,64,6452,0.532223636,0.883467848,0.612817893,1.273298174,0.68905507,DB0053110003997_,0.372434084,-0.12390038,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,76489,DB00541,10003997,48,3086,65,4232,1,1.012693386,0.68041137,1.498012745,1,DB0054110003997_,0,0.012613501,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,vincristine,DB00541
,76492,DB00787,10003997,31,16969,57,17191,0.00740266,0.550987332,0.343651525,0.868416737,0.028003011,DB0078710003997_,3.575443226,-0.59604346,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,acyclovir,DB00787
,76493,DB00997,10003997,32,5299,31,3483,0.154602649,0.678545046,0.400137389,1.152024851,0.290276686,DB0099710003997_,1.236920723,-0.387804411,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,doxorubicin,DB00997
,76496,DB01234,10003997,52,31573,99,32789,0.000318343,0.545489868,0.382070078,0.770921354,0.002117857,DB0123410003997_,6.157350662,-0.606071049,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,76518,DB00531,10018838,69,7183,119,6397,1.22581261755779e-05,0.516413376,0.377448914,0.701917146,0.000129764,DB0053110018838_,8.949790552,-0.660847718,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,cyclophosphamide,DB00531
,76522,DB00787,10018838,42,16958,29,17219,0.122494816,1.470541961,0.89420139,2.449123809,0.245028769,DB0078710018838_,1.40637965,0.385631014,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,acyclovir,DB00787
,76525,DB01234,10018838,54,31571,51,32837,0.626854617,1.101275979,0.736777499,1.648109436,0.766330571,DB0123410018838_,0.266141647,0.096469488,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,76526,DB00019,10018884,30,18982,25,9504,0.063176629,0.600816898,0.341369298,1.066100676,0.149267208,DB0001910018884_,1.902017234,-0.509465053,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,pegfilgrastim,DB00019
,76527,DB00188,10018884,116,7770,127,8701,0.897049247,1.022831332,0.786732161,1.328704881,0.956338178,DB0018810018884_,0.044643686,0.022574598,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,bortezomib,DB00188
,76529,DB00476,10018884,85,17172,41,6136,0.12782031,0.7408078,0.503959383,1.104581931,0.25258481,DB0047610018884_,1.376008206,-0.300014066,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,duloxetine,DB00476
,76530,DB00697,10018884,39,6057,18,1788,0.11562526,0.639631379,0.356266597,1.191016206,0.23461556,DB0069710018884_,1.449807018,-0.446863238,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,tizanidine,DB00697
,76531,DB00019,10021789,31,18981,22,9507,0.243056635,0.70575618,0.395425037,1.280085463,0.401361768,DB0001910021789_,0.912892094,-0.348485456,NA,10021789,Infection,10021881,Infections and infestations,Infec,pegfilgrastim,DB00019
,76533,DB00476,10021789,141,17116,46,6131,0.617923869,1.097964323,0.780927064,1.568923012,0.758853874,DB0047610021789_,0.275946044,0.09345785,NA,10021789,Infection,10021881,Infections and infestations,Infec,duloxetine,DB00476
,76534,DB00697,10021789,84,6012,19,1787,0.344370441,1.314056262,0.788986871,2.296907643,0.513716953,DB0069710021789_,0.66608284,0.273118736,NA,10021789,Infection,10021881,Infections and infestations,Infec,tizanidine,DB00697
,76536,DB00787,10021789,178,16822,184,17064,0.874142806,0.981306105,0.793160299,1.213870672,0.945393501,DB0078710021789_,0.056154035,-0.018870835,NA,10021789,Infection,10021881,Infections and infestations,Infec,acyclovir,DB00787
,76537,DB01175,10021789,104,10620,38,4854,0.275343333,1.250860739,0.853607583,1.867830156,0.438670152,DB0117510021789_,0.824007511,0.223831906,NA,10021789,Infection,10021881,Infections and infestations,Infec,escitalopram,DB01175
,76545,DB00531,10025256,87,7165,111,6405,0.014649116,0.70067032,0.521916534,0.938133569,0.048391157,DB0053110025256_,3.02843818,-0.355717802,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,cyclophosphamide,DB00531
,76553,DB01234,10025256,38,31587,24,32864,0.056990647,1.647319925,0.962643854,2.871504529,0.137759715,DB0123410025256_,1.982244304,0.49914968,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,76554,DB00073,10029366,51,7355,90,6317,3.91986637532733e-05,0.486723974,0.33767698,0.695005894,0.000358503,DB0007310029366_,7.933574253,-0.720058105,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,rituximab,DB00073
,76555,DB00188,10029366,58,7828,54,8774,0.343261099,1.203857858,0.815440391,1.77982773,0.512546823,DB0018810029366_,0.668363211,0.185531282,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,bortezomib,DB00188
,76557,DB00541,10029366,39,3095,75,4222,0.085961715,0.709383046,0.467598078,1.061381383,0.18827046,DB0054110029366_,1.669875734,-0.343359635,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,vincristine,DB00541
,76559,DB00997,10029366,76,5255,49,3465,0.9269392,1.022698144,0.702969442,1.499927037,0.969118049,DB0099710029366_,0.031368849,0.022444374,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,doxorubicin,DB00997
,76560,DB01137,10029366,40,7732,35,5558,0.412778818,0.821537987,0.508074893,1.333931919,0.582185025,DB0113710029366_,0.540966969,-0.196577102,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,levofloxacin,DB01137
,76572,DB00787,10031009,33,16967,17,17231,0.023159762,1.9713305,1.066506898,3.775386724,0.069275033,DB0078710031009_,2.669670718,0.678708695,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,76576,DB01234,10031009,80,31545,53,32835,0.011585171,1.571139019,1.096232998,2.267915427,0.040052113,DB0123410031009_,3.21757384,0.451800846,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,76579,DB00188,10038153,39,7847,53,8775,0.402462749,0.822882198,0.529222523,1.269583605,0.572271963,DB0018810038153_,0.558140941,-0.194942226,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,bortezomib,DB00188
,76587,DB00787,10038153,100,16900,115,17133,0.374173915,0.88155763,0.666879778,1.163701913,0.544010252,DB0078710038153_,0.608787186,-0.126064902,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,acyclovir,DB00787
,76589,DB01234,10038153,157,31468,147,32741,0.38844203,1.111230656,0.881204611,1.401943762,0.558437868,DB0123410038153_,0.582611914,0.1054681,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,76590,DB00227,10040047,27,2440,30,1773,0.136862077,0.654054844,0.372684149,1.142814368,0.265306219,DB0022710040047_,1.326870576,-0.424564072,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,lovastatin,DB00227
,76591,DB00697,10040047,54,6042,24,1782,0.103573906,0.663643291,0.401978289,1.125948823,0.216392984,DB0069710040047_,1.530659155,-0.410010486,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,tizanidine,DB00697
,76593,DB00019,10042128,43,18969,13,9516,0.119273863,1.659311859,0.875299054,3.365126607,0.240220174,DB0001910042128_,1.426199383,0.506402973,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,pegfilgrastim,DB00019
,76594,DB00073,10042128,43,7363,23,6384,0.063866094,1.620923964,0.954176434,2.82110432,0.150422963,DB0007310042128_,1.894304196,0.482996335,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,rituximab,DB00073
,76597,DB00433,10042128,98,7558,49,5971,0.009430986,1.579993657,1.108231654,2.278225684,0.033962663,DB0043310042128_,3.382493514,0.457420833,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,76598,DB00437,10042128,46,6875,72,11474,0.774884017,1.066266315,0.719133363,1.567046869,0.877304578,DB0043710042128_,0.130901052,0.064163121,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,76599,DB00476,10042128,70,17187,17,6160,0.179356158,1.475738334,0.858500795,2.677274451,0.323079537,DB0047610042128_,1.129856741,0.38915843,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,76600,DB00531,10042128,94,7158,74,6442,0.437022954,1.143196177,0.832388615,1.57497844,0.60559076,DB0053110042128_,0.501550834,0.133828004,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,76601,DB00541,10042128,57,3077,43,4254,0.002985261,1.832442828,1.208291568,2.797348674,0.013452354,DB0054110042128_,4.308601199,0.605649955,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,vincristine,DB00541
,76604,DB00787,10042128,129,16871,70,17178,1.7610517967126e-05,1.87634538,1.390869577,2.549381454,0.000178482,DB0078710042128_,8.631024103,0.629325938,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,76605,DB00997,10042128,128,5203,49,3465,0.000820868,1.739550154,1.238511709,2.477196603,0.004678342,DB0099710042128_,5.364811543,0.553626547,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,doxorubicin,DB00997
,76606,DB01175,10042128,57,10667,17,4875,0.132411048,1.532312596,0.877605581,2.812988898,0.259133676,DB0117510042128_,1.350411225,0.426778095,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,76607,DB00019,10047942,260,18752,89,9440,0.001643817,1.470625947,1.150171216,1.89498053,0.008280516,DB0001910047942_,4.793849935,0.385688124,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,pegfilgrastim,DB00019
,76608,DB00188,10047942,184,7702,192,8636,0.497417267,1.074521961,0.870896373,1.32545799,0.659595353,DB0018810047942_,0.416128734,0.071875875,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,bortezomib,DB00188
,76609,DB00227,10047942,39,2428,23,1780,0.439541433,1.243043028,0.721206139,2.188357428,0.607910896,DB0022710047942_,0.497726961,0.217562428,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,lovastatin,DB00227
,76610,DB00327,10047942,51,6087,54,4208,0.035734756,0.652946369,0.435525488,0.977707496,0.096958768,DB0032710047942_,2.333469459,-0.426260284,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,hydromorphone,DB00327
,76611,DB00437,10047942,150,6771,234,11312,0.522939826,1.070927417,0.864529173,1.323321156,0.68132907,DB0043710047942_,0.383709874,0.068525018,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,allopurinol,DB00437
,76612,DB00531,10047942,212,7040,225,6291,0.079701509,0.841989554,0.69241736,1.023559108,0.177922984,DB0053110047942_,1.726404496,-0.171987671,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,cyclophosphamide,DB00531
,76613,DB00787,10047942,502,16498,470,16778,0.20460408,1.086189117,0.954105176,1.236804201,0.354610197,DB0078710047942_,1.036736129,0.082675347,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,acyclovir,DB00787
,76614,DB00997,10047942,106,5225,67,3447,0.814289008,1.043724417,0.759040696,1.443765135,0.900388557,DB0099710047942_,0.104928879,0.042795486,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,doxorubicin,DB00997
,76615,DB01137,10047942,110,7662,110,5483,0.015706398,0.715639276,0.543112676,0.942995287,0.051113369,DB0113710047942_,2.973709185,-0.334579044,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,levofloxacin,DB01137
,76622,DB00295,10010071,41,14622,28,9574,0.90210893,0.958797164,0.578296855,1.611024783,0.957195726,DB0029510010071_,0.043747388,-0.042075735,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,morphine,DB00295
,76626,DB00956,10033295,72,5742,59,3408,0.069368571,0.724343923,0.504836603,1.042765479,0.160182103,DB0095610033295_,1.831443967,-0.322488968,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocodone,DB00956
,76627,DB00956,10051398,20,5794,39,3428,9.1125904513725e-06,0.303448869,0.167423585,0.534084465,0.000100178,DB0095610051398_,9.208566789,-1.192542154,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,hydrocodone,DB00956
,76633,DB09072,10024855,62,6409,27,2508,0.636793833,0.898615251,0.56181888,1.472662318,0.774232199,DB0907210024855_,0.255883452,-0.10690031,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,76640,DB01238,10013983,36,5214,50,3452,0.000808947,0.476720583,0.301054589,0.748280291,0.004618411,DB0123810013983_,5.377704665,-0.740824739,NA,10013983,Dystonia,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,76641,DB00472,10017577,129,10630,42,4270,0.268648264,1.233740373,0.863094055,1.795370665,0.431079197,DB0047210017577_,0.841463455,0.210050509,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,76642,DB01238,10017577,72,5178,42,3460,0.50247456,1.145526996,0.770263142,1.722624607,0.663695668,DB0123810017577_,0.409931565,0.13586479,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,76645,DB01238,10052904,35,5215,24,3478,1,0.972584444,0.561182582,1.712205922,1,DB0123810052904_,0,-0.027798376,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,aripiprazole,DB01238
,76646,DB00203,10005750,77,13801,50,8888,1,0.991776383,0.685077061,1.447093388,1,DB0020310005750_,0,-0.008257617,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,sildenafil,DB00203
,76654,DB00555,10020772,64,6983,24,3462,0.257674342,1.322070646,0.813757042,2.214491996,0.418536696,DB0055510020772_,0.870990708,0.279199178,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,lamotrigine,DB00555
,76656,DB09072,10029148,50,6421,25,2510,0.305322169,0.78181511,0.473418406,1.321962583,0.47213978,DB0907210029148_,0.750480192,-0.246136998,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,sodium oxybate,DB09072
,76664,DB00555,10061920,39,7008,22,3464,0.682443153,0.876263006,0.505945616,1.554154669,0.807946053,DB0055510061920_,0.213259989,-0.132088998,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,76672,DB00108,10048737,68,10126,16,3279,0.307771665,1.376184784,0.788333147,2.546212267,0.474947351,DB0010810048737_,0.744551322,0.319315021,NA,10048737,Poor venous access,10047065,Vascular disorders,Vasc,natalizumab,DB00108
,76684,DB00575,10016173,153,5091,80,3749,0.015397514,1.408307168,1.063966928,1.875817934,0.050326244,DB0057510016173_,2.989228595,0.342388393,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,clonidine,DB00575
,76685,DB00575,10033295,96,5148,55,3774,0.158107001,1.279558277,0.9065819,1.821481301,0.294928857,DB0057510033295_,1.221021116,0.246514922,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,clonidine,DB00575
,76688,DB00181,10015150,46,9810,30,5841,0.722041345,0.912973194,0.563380955,1.499736751,0.836257182,DB0018110015150_,0.178819079,-0.091048759,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,baclofen,DB00181
,76689,DB00327,10015150,43,6095,15,4247,0.022120617,1.997363647,1.086107608,3.875995509,0.066912989,DB0032710015150_,2.704362175,0.691828134,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,hydromorphone,DB00327
,76690,DB00327,10042674,43,6095,22,4240,0.257250522,1.359644016,0.794190037,2.390510056,0.418119588,DB0032710042674_,0.871987793,0.307222913,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,76693,DB00060,10007559,37,9471,13,2452,0.379383592,0.736877514,0.38210318,1.513213452,0.549396602,DB0006010007559_,0.59893469,-0.305333596,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,interferon beta-1a,DB00060
,76702,DB00736,10007739,48,10543,22,5531,0.705446169,1.144590987,0.676890727,1.99329161,0.82351398,DB0073610007739_,0.194174753,0.135047357,NA,10007739,Cataract,10015919,Eye disorders,Eye,esomeprazole,DB00736
,76705,DB00736,10016454,43,10548,7,5546,0.001582334,3.229646595,1.439191571,8.514827255,0.008024607,DB0073610016454_,4.825242527,1.172372718,female,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,esomeprazole,DB00736
,76712,DB00736,10021097,143,10448,64,5489,0.303334786,1.173829325,0.866571617,1.605061155,0.469852079,DB0073610021097_,0.75533736,0.160271332,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,esomeprazole,DB00736
,76716,DB00736,10028391,60,10531,26,5527,0.494782305,1.211105823,0.751665443,2.001872976,0.657228907,DB0073610028391_,0.419722909,0.191533845,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,76718,DB01373,10029148,77,22643,30,7351,0.430362411,0.83324424,0.539497824,1.317586957,0.598839385,DB0137310029148_,0.512761856,-0.182428475,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,calcium,DB01373
,76724,DB00736,10031161,58,10533,13,5540,0.003726096,2.346510899,1.269323697,4.672105531,0.016100635,DB0073610031161_,4.128896588,0.852929501,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,76727,DB01373,10039227,42,22678,8,7373,0.189259282,1.706772829,0.791161361,4.21112838,0.335616814,DB0137310039227_,1.091785203,0.534604353,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,76729,DB01373,10039674,62,22658,13,7368,0.178487851,1.55081168,0.843328125,3.076315028,0.321956709,DB0137310039674_,1.133338186,0.438778458,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,calcium,DB01373
,76734,DB00736,10046306,98,10493,36,5517,0.068025667,1.431257511,0.966187408,2.162712047,0.15775329,DB0073610046306_,1.846722924,0.358553436,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,76735,DB00736,10047461,46,10545,16,5537,0.180566042,1.509577547,0.837945736,2.859363508,0.32452502,DB0073610047461_,1.125392643,0.411829841,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,76738,DB00736,10050584,117,10474,31,5522,0.000463864,1.989717605,1.327447853,3.063985151,0.002901166,DB0073610050584_,5.842642613,0.687992721,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,esomeprazole,DB00736
,76744,DB00736,10055798,53,10538,30,5523,0.729449614,0.925921595,0.580153902,1.502892344,0.842369049,DB0073610055798_,0.17153706,-0.076965718,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,esomeprazole,DB00736
,76745,DB01373,10061623,172,22548,82,7299,0.005254324,0.679010088,0.518277505,0.895682091,0.021277139,DB0137310061623_,3.850122047,-0.387119295,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,76760,DB00108,10037377,63,10131,18,3277,0.699047308,1.132107643,0.660707955,2.034801078,0.819056632,DB0010810037377_,0.19960205,0.124081066,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,natalizumab,DB00108
,76763,DB01156,10037377,65,13557,31,6297,0.912654858,0.973893999,0.624967749,1.547558986,0.960814377,DB0115610037377_,0.039974045,-0.026452812,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,76770,DB01224,10010305,182,7926,210,5707,4.63877178953256e-06,0.624066354,0.507330176,0.76706939,5.54353791715678e-05,DB0122410010305_,9.800292555,-0.471498579,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,76772,DB00563,10039101,204,46442,53,15295,0.128690708,1.267616992,0.932346986,1.750061876,0.253754017,DB0056310039101_,1.371389919,0.237138754,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,76784,DB00656,10060795,52,11961,10,6609,0.001217284,2.873097772,1.443237386,6.345043407,0.00647371,DB0065610060795_,5.040005964,1.055390811,female,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,trazodone,DB00656
,76785,DB01050,10060795,80,18028,28,9343,0.083403372,1.480692646,0.951305272,2.36748841,0.184122759,DB0105010060795_,1.692152574,0.392509983,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,ibuprofen,DB01050
,76787,DB00316,10013654,711,64763,738,36215,3.79309247456919e-31,0.538719176,0.484924029,0.598512221,9.1051539446622e-29,DB0031610013654_,64.56612708,-0.618560853,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,76789,DB00813,10013654,855,9717,2017,8151,3.33217724631831e-135,0.355598129,0.326137958,0.387481547,1.3474812141458e-131,DB0081310013654_,301.3404101,-1.033954037,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,fentanyl,DB00813
,76791,DB01075,10013654,587,19361,732,10365,2.5384294423823e-50,0.429316174,0.383449927,0.480501681,1.51642313393225e-47,DB0107510013654_,107.805145,-0.84556163,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,76793,DB00660,10033295,49,1208,15,352,0.878976123,0.951901441,0.517439941,1.850574675,0.94911728,DB0066010033295_,0.052222905,-0.049293778,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,metaxalone,DB00660
,76803,DB00316,10038540,43,65431,41,36912,0.016947177,0.591628268,0.376567361,0.930855827,0.054252057,DB0031610038540_,2.914114377,-0.524876767,NA,10038540,Renal tubular necrosis,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,76810,DB00404,10038678,31,19861,41,9821,4.23127861999706e-05,0.373892641,0.226573517,0.611363895,0.000383118,DB0040410038678_,7.867167494,-0.983786579,NA,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,76812,DB00813,10038678,76,10496,98,10070,0.056926231,0.744048388,0.543348337,1.015626483,0.137656619,DB0081310038678_,1.982992966,-0.295649209,NA,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,76816,DB00404,10039020,38,19854,31,9831,0.040806903,0.606972245,0.367507676,1.009530761,0.107256692,DB0040410039020_,2.232530329,-0.499272214,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,76824,DB01075,10054889,33,19915,29,11068,0.083899534,0.632400503,0.372066025,1.080315197,0.184910448,DB0107510054889_,1.687883636,-0.458232378,NA,10054889,Transaminases increased,10022891,Investigations,Inv,diphenhydramine,DB01075
,76825,DB01075,10013887,50,19898,38,11059,0.14876528,0.731327428,0.469756859,1.146847743,0.282291033,DB0107510013887_,1.264816709,-0.312894002,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,76843,DB00334,10012218,56,2793,73,2739,0.129719077,0.752332216,0.519253001,1.085073856,0.255271837,DB0033410012218_,1.365426274,-0.284577275,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,76844,DB00334,10013654,34,2815,55,2757,0.024463414,0.605501898,0.381475387,0.948747013,0.072318601,DB0033410013654_,2.626673907,-0.501697581,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,76845,DB00425,10013654,117,12578,138,7346,3.14625467131805e-08,0.495167953,0.383038797,0.639271616,6.33711142035211e-07,DB0042510013654_,14.2716726,-0.702858275,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,76847,DB00425,10013663,36,12659,25,7459,0.595689689,0.848497487,0.495013578,1.475852759,0.74122358,DB0042510013663_,0.299452972,-0.164288156,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,76852,DB01261,10012607,51,3730,50,3253,0.615731016,0.889575823,0.588502224,1.345239878,0.757025585,DB0126110012607_,0.278358228,-0.117010533,NA,10012607,Diabetes mellitus inadequate control,10027433,Metabolism and nutrition disorders,Metab,sitagliptin,DB01261
,76854,DB00722,10047571,141,25262,112,25920,0.043837989,1.291709542,1.000122085,1.671581078,0.113251908,DB0072210047571_,2.178140667,0.255966567,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,lisinopril,DB00722
,76856,DB00227,10047899,43,2424,23,1780,0.258619739,1.372765363,0.805713353,2.395779279,0.419670319,DB0022710047899_,0.86828583,0.316827218,NA,10047899,Weight increased,10022891,Investigations,Inv,lovastatin,DB00227
,76857,DB00227,10061428,50,2417,40,1763,0.667732389,0.911791449,0.586700073,1.425103749,0.798169392,DB0022710061428_,0.225434433,-0.092343989,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,lovastatin,DB00227
,76859,DB01261,10061428,61,3720,70,3233,0.132657084,0.757380649,0.526506307,1.086903503,0.259528224,DB0126110061428_,1.348889819,-0.277889313,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,sitagliptin,DB01261
,76868,DB00316,10048393,364,65110,83,36870,5.65824334562592e-16,2.483388288,1.950998624,3.19248825,3.88828565594189e-14,DB0031610048393_,30.87822295,0.909623873,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,76874,DB00540,10016322,50,2433,17,1074,0.422150605,1.298192542,0.731986356,2.41276456,0.591215529,DB0054010016322_,0.525574643,0.260972945,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,nortriptyline,DB00540
,76875,DB00669,10016322,108,6269,11,1086,0.115496006,1.70073066,0.9097258,3.519933632,0.234434728,DB0066910016322_,1.450578073,0.531057959,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,76876,DB01268,10016322,47,2096,58,3072,0.422262472,1.187635484,0.787463737,1.783157154,0.591324938,DB0126810016322_,0.525389603,0.171964342,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,76885,DB00788,10043414,36,9320,15,5046,0.463474235,1.299401165,0.693073817,2.557157755,0.630674307,DB0078810043414_,0.460965703,0.261903516,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,76894,DB00788,10061623,50,9306,24,5037,0.714532194,1.127614827,0.679170222,1.920922338,0.830796075,DB0078810061623_,0.185370912,0.12010463,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,76897,DB00222,10012378,35,3171,23,3105,0.147934696,1.489966504,0.853634839,2.647778779,0.281110679,DB0022210012378_,1.26900681,0.398753639,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,glimepiride,DB00222
,76901,DB00588,10042609,93,16431,22,8446,0.000709508,2.172878758,1.352694523,3.636010982,0.004140175,DB0058810042609_,5.487017244,0.776052905,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,fluticasone propionate,DB00588
,76903,DB00924,10042609,64,10098,14,4237,0.024755635,1.918042163,1.062770076,3.708182615,0.072956819,DB0092410042609_,2.617887536,0.651304959,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,cyclobenzaprine,DB00924
,76906,DB00177,10061024,34,4766,16,2834,0.467629693,1.263565499,0.677231195,2.456127267,0.634174213,DB0017710061024_,0.455431578,0.233937486,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,valsartan,DB00177
,76907,DB00482,10061024,41,8218,19,3052,0.466304979,0.801395211,0.453894684,1.464373274,0.633093464,DB0048210061024_,0.457137215,-0.221401057,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,celecoxib,DB00482
,76909,DB00924,10061024,43,10119,14,4237,0.469031486,1.286011111,0.689251328,2.548176031,0.635390263,DB0092410061024_,0.453515882,0.251545266,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,cyclobenzaprine,DB00924
,76914,DB06643,10062544,268,52153,25,7490,0.041330513,1.539551759,1.019544513,2.423615587,0.108398113,DB0664310062544_,2.2219446,0.431491308,NA,10062544,Tooth fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,76924,DB00316,10067125,90,65384,48,36905,0.790649008,1.058318953,0.737336544,1.535653353,0.886594108,DB0031610067125_,0.120368003,0.056681756,NA,10067125,Liver injury,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,76926,DB00997,10037377,76,5255,53,3461,0.785892794,0.944436046,0.654490328,1.37148553,0.883799408,DB0099710037377_,0.123525156,-0.057167306,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxorubicin,DB00997
,76930,DB01229,10061169,36,5705,17,2692,1,0.999276792,0.54578516,1.900727634,1,DB0122910061169_,0,-0.00072347,NA,10061169,Embolism,10047065,Vascular disorders,Vasc,paclitaxel,DB01229
,76937,DB00331,10015916,52,24894,26,20726,0.039830776,1.665117962,1.020595735,2.779134621,0.105350366,DB0033110015916_,2.250463667,0.509895969,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,metformin,DB00331
,76978,DB00425,10013950,76,12619,38,7446,0.437630384,1.180151519,0.788460703,1.792882135,0.606081729,DB0042510013950_,0.500740436,0.165642836,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,76979,DB00706,10013950,12,1063,128,15797,0.291306612,1.393154448,0.699166022,2.529529183,0.456752226,DB0070610013950_,0.783614211,0.331570563,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,tamsulosin,DB00706
,76980,DB00741,10013950,47,4047,18,3156,0.011414183,2.036031898,1.157741564,3.732536225,0.039575493,DB0074110013950_,3.229545213,0.711002766,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,hydrocortisone,DB00741
,76983,DB00338,10016165,28,33646,31,22241,0.061479122,0.597083174,0.344980214,1.029108303,0.146176274,DB0033810016165_,1.922942027,-0.515698856,NA,10016165,Failure to thrive,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,77008,DB00706,10035226,7,1068,192,15733,0.107611627,0.537068229,0.212532575,1.132112567,0.222581966,DB0070610035226_,1.502459858,-0.621630136,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,tamsulosin,DB00706
,77009,DB00741,10035226,21,4073,32,3142,0.017466793,0.506301458,0.276874997,0.907496718,0.055562707,DB0074110035226_,2.890243036,-0.68062302,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,hydrocortisone,DB00741
,77011,DB00997,10035226,30,5301,38,3476,0.008522247,0.517706757,0.309143847,0.859933258,0.031331879,DB0099710035226_,3.463119191,-0.658346303,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,doxorubicin,DB00997
,77013,DB00874,10040047,45,3290,49,1927,0.003448239,0.537949988,0.34934261,0.826735545,0.015138963,DB0087410040047_,4.190483527,-0.619989682,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,guaifenesin,DB00874
,77016,DB01190,10015150,52,4882,30,2255,0.340701509,0.800677561,0.499799831,1.303750392,0.509941585,DB0119010015150_,0.673459098,-0.222296958,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,clindamycin,DB01190
,77026,DB00203,10038683,72,13806,28,8910,0.023582106,1.659490361,1.057919996,2.669935435,0.07025054,DB0020310038683_,2.655687277,0.506510544,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,77028,DB00203,10041349,149,13729,69,8869,0.025463586,1.39497593,1.040394236,1.886161734,0.074525147,DB0020310041349_,2.596618666,0.332877161,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,77029,DB00559,10041349,59,9600,17,3289,0.598829689,1.18901801,0.68256771,2.179127857,0.743639164,DB0055910041349_,0.296199356,0.173127765,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,bosentan,DB00559
,77039,DB00203,10052428,37,13841,16,8922,0.205792359,1.490627173,0.808499895,2.87189378,0.356188204,DB0020310052428_,1.032296024,0.399196953,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,77042,DB00203,10013911,31,13847,23,8915,0.675799903,0.867768686,0.489455712,1.559611299,0.803537442,DB0020310013911_,0.218731497,-0.141830091,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,77046,DB00843,10008190,37,2157,28,2145,0.317816149,1.313991299,0.779491796,2.237773755,0.485728259,DB0084310008190_,0.722105949,0.273069298,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,donepezil,DB00843
,77047,DB00177,10027175,61,4739,28,2822,0.271982053,1.2972624,0.814354287,2.113376667,0.434843724,DB0017710027175_,0.832768567,0.260256198,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,valsartan,DB00177
,77048,DB00641,10027175,146,13978,79,12396,0.000362403,1.638901673,1.23667082,2.185649602,0.002361367,DB0064110027175_,6.048514786,0.494026306,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,77049,DB00843,10027175,47,2147,41,2132,0.59089561,1.138298104,0.729364633,1.78281434,0.737392162,DB0084310027175_,0.304635423,0.129534256,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,donepezil,DB00843
,77054,DB00177,10047513,51,4749,21,2829,0.178075777,1.446644082,0.852724127,2.537736066,0.321400886,DB0017710047513_,1.13506607,0.369246448,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,valsartan,DB00177
,77056,DB01104,10047513,142,15321,42,7244,0.006874568,1.598535122,1.124388131,2.315390143,0.026423635,DB0110410047513_,3.633496391,0.469087661,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,sertraline,DB01104
,77059,DB00338,10019663,40,33634,42,22230,0.041622708,0.629489111,0.397718725,0.994886091,0.108969411,DB0033810019663_,2.216688067,-0.462846723,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,omeprazole,DB00338
,77060,DB00421,10019663,30,8873,43,5209,0.000213769,0.409602387,0.247746525,0.66916692,0.001523363,DB0042110019663_,6.486834917,-0.892568379,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,spironolactone,DB00421
,77065,DB00338,10037400,132,33542,82,22190,0.675231418,1.064955823,0.801913769,1.421318396,0.80311581,DB0033810037400_,0.219256354,0.062933317,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,77066,DB00421,10037400,191,8712,75,5177,0.002534802,1.513283327,1.150031663,2.008561777,0.011788267,DB0042110037400_,4.44065059,0.414281679,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,77068,DB00996,10037400,116,38837,56,22369,0.302946002,1.193048298,0.85965991,1.67276266,0.469341001,DB0099610037400_,0.756425694,0.176511627,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,77083,DB00331,10033609,61,24885,71,20681,0.05447772,0.714023574,0.498396932,1.020302482,0.133409127,DB0033110033609_,2.014334731,-0.336839301,NA,10033609,Pancreatic carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metformin,DB00331
,77091,DB00374,10020642,132,17584,26,5698,0.019830393,1.645061041,1.072880448,2.614057415,0.061347836,DB0037410020642_,2.791195385,0.497777491,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,treprostinil,DB00374
,77095,DB00181,10000060,40,9816,28,5843,0.53104427,0.850375838,0.511116862,1.432915811,0.687912749,DB0018110000060_,0.374093268,-0.162076865,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,baclofen,DB00181
,77097,DB14513,10000060,77,7100,29,3535,0.214796215,1.321978285,0.850479794,2.106280825,0.367173112,DB1451310000060_,1.001921847,0.279129315,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,77103,DB05259,10006784,105,11165,27,2701,0.741441822,0.940782814,0.610015096,1.49751551,0.851727304,DB0525910006784_,0.16048887,-0.061042969,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,77104,DB14513,10006784,41,7136,17,3547,0.578527072,1.198744259,0.66508058,2.253837467,0.727257184,DB1451310006784_,0.318475104,0.181274558,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,77105,DB14513,10013700,72,7105,23,3541,0.063393647,1.560090949,0.962021625,2.619576221,0.149638108,DB1451310013700_,1.899535514,0.44474412,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,magnesium,DB14513
,77106,DB00169,10022081,103,38588,17,18158,1.22381082545399e-05,2.85100064,1.696204519,5.084357018,0.000129605,DB0016910022081_,8.9510221,1.047670034,female,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,77107,DB00451,10022081,116,47155,14,15405,9.44212601135167e-05,2.706933811,1.54926771,5.106279151,0.000758802,DB0045110022081_,7.183769995,0.995816559,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,77108,DB00996,10022081,121,38832,39,22386,0.00127766,1.788559399,1.236924394,2.637350381,0.006729447,DB0099610022081_,5.001262382,0.581410491,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,77109,DB05259,10022081,484,10786,76,2652,0.00020702,1.565762346,1.222298318,2.029009831,0.001482781,DB0525910022081_,6.513835801,0.448372827,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,77111,DB00181,10022086,82,9774,19,5852,7.2534194152284e-05,2.583859069,1.552350939,4.513225603,0.000605065,DB0018110022086_,7.410173892,0.949284044,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,77112,DB00996,10022086,410,38543,99,22326,4.01919257563417e-17,2.398875829,1.92046246,3.02081595,3.12095943428491e-15,DB0099610022086_,33.40063593,0.875000223,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,77113,DB14513,10022086,75,7102,17,3547,0.002472123,2.203258642,1.286330524,3.985951899,0.01156635,DB1451310022086_,4.459655226,0.789937465,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,77114,DB00169,10022093,236,38455,20,18155,1.68948204644809e-20,5.571150708,3.524884635,9.290014596,1.83125919962425e-18,DB0016910022093_,40.84152786,1.717601623,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,77117,DB00169,10022095,325,38366,36,18139,5.59771054822503e-23,4.268638459,3.017872819,6.204870005,7.60391843721421e-21,DB0016910022095_,46.32562325,1.451294914,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,77118,DB00181,10022095,76,9780,15,5856,1.71370662043683e-05,3.033594843,1.726653617,5.688918777,0.000174322,DB0018110022095_,8.654606978,1.109748333,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,77120,DB00169,10023230,96,38595,16,18159,2.53950338902658e-05,2.822964636,1.652139083,5.138512229,0.000244912,DB0016910023230_,8.314610382,1.037787622,female,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,77122,DB14513,10028391,53,7124,15,3549,0.052863607,1.760135615,0.975785546,3.36693087,0.130434611,DB1451310028391_,2.036883241,0.56539086,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,77123,DB00169,10029223,110,38581,36,18139,0.061940969,1.43658706,0.977511258,2.156405964,0.147048263,DB0016910029223_,1.916994423,0.362270203,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,77124,DB00181,10029223,46,9810,24,5847,0.623065636,1.142396068,0.6821809,1.958918298,0.763207132,DB0018110029223_,0.270225815,0.133127871,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,77125,DB00451,10029223,98,47173,23,15396,0.169884717,1.390605639,0.875645297,2.296337014,0.310756797,DB0045110029223_,1.168744676,0.329739364,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,77128,DB05259,10033775,216,11054,41,2687,0.176168379,1.280588696,0.910902257,1.839820361,0.318921854,DB0525910033775_,1.14280918,0.247319891,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,77129,DB05259,10037087,251,11019,61,2667,1,0.995920847,0.747544689,1.344437115,1,DB0525910037087_,0,-0.004087495,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,glatiramer,DB05259
,77130,DB00181,10047513,93,9763,36,5835,0.028033741,1.543926313,1.038791543,2.33935523,0.08029967,DB0018110047513_,2.521989767,0.434328726,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,baclofen,DB00181
,77131,DB05259,10047513,80,11190,22,2706,0.615469067,0.879340461,0.541769978,1.48367384,0.756846991,DB0525910047513_,0.278594172,-0.128583129,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,glatiramer,DB05259
,77132,DB00996,10061224,134,38819,47,22378,0.003196054,1.643540329,1.170236847,2.343867678,0.014248349,DB0099610061224_,4.251114207,0.496852652,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,77135,DB08932,10005802,65,19378,19,6578,0.617285059,1.161291257,0.6871102,2.052532695,0.758352821,DB0893210005802_,0.276606538,0.149532538,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,macitentan,DB08932
,77136,DB00115,10048393,209,18216,47,10425,4.98371818516228e-10,2.544829567,1.845094908,3.57418832,1.46202045197534e-08,DB0011510048393_,18.04086139,0.93406368,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,77138,DB00181,10048393,464,9392,113,5758,7.41022154960475e-21,2.517264653,2.039480678,3.128365936,8.54288041365617e-19,DB0018110048393_,41.60401853,0.923172857,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,77139,DB00706,10048393,39,1036,38,15887,1.184527026245e-26,15.7288274,9.756111368,25.39265157,2.061939926149e-24,DB0070610048393_,54.53839498,2.755495169,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,77158,DB00722,10014011,45,25358,33,25999,0.173491698,1.398090801,0.872186246,2.262381938,0.315499465,DB0072210014011_,1.153598291,0.335107592,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,lisinopril,DB00722
,77160,DB00722,10019974,121,25282,58,25974,9.14489941228817e-07,2.143266186,1.553931107,2.985724726,1.32510298264606e-05,DB0072210019974_,11.23143529,0.762330921,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,lisinopril,DB00722
,77161,DB08908,10019974,89,10584,33,3246,0.336634147,0.827127679,0.54785433,1.27617682,0.505667832,DB0890810019974_,0.681875284,-0.189796208,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,dimethyl fumarate,DB08908
,77176,DB01098,10013709,370,7779,272,6937,0.01907733,1.213039184,1.030902509,1.428737044,0.059540207,DB0109810013709_,2.821103442,0.193128933,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,77186,DB00736,10003481,38,10553,19,5534,1,1.048800751,0.589182335,1.927954871,1,DB0073610003481_,0,0.04764737,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,esomeprazole,DB00736
,77200,DB00736,10018884,107,10484,53,5500,0.80199156,1.059116149,0.753806705,1.503691688,0.892894581,DB0073610018884_,0.113286756,0.057434739,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,esomeprazole,DB00736
,77201,DB01275,10018884,55,3924,50,3299,0.694411624,0.924810985,0.61713924,1.388699456,0.816050858,DB0127510018884_,0.2032786,-0.078165903,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,hydralazine,DB01275
,77206,DB00736,10035528,73,10518,62,5491,0.006135427,0.614678855,0.43144472,0.878186447,0.024089881,DB0073610035528_,3.725963386,-0.486655335,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,esomeprazole,DB00736
,77208,DB01275,10035528,36,3943,25,3324,0.519435254,1.213905929,0.707169311,2.114486841,0.678629935,DB0127510035528_,0.387679315,0.193843201,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,hydralazine,DB01275
,77219,DB01015,10002855,125,9762,49,9332,4.16773188118541e-08,2.438367841,1.737029184,3.470734389,8.18329416098773e-07,DB0101510002855_,14.01600087,0.891328898,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,sulfamethoxazole,DB01015
,77221,DB01015,10013710,144,9743,117,9264,0.213033734,1.170249816,0.908951503,1.509227972,0.365079652,DB0101510013710_,1.007639726,0.157217244,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,77222,DB09065,10013710,44,708,90,1847,0.20016288,1.27530329,0.859063747,1.869771399,0.349180774,DB0906510013710_,1.052165514,0.243184025,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,cobicistat,DB09065
,77223,DB00338,10026749,30,33644,29,22243,0.145522698,0.683947479,0.396499534,1.181273567,0.277772347,DB0033810026749_,1.280953396,-0.379874149,NA,10026749,Mania,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,77240,DB01409,10020100,35,5996,18,3948,0.481848023,1.280262342,0.704555045,2.404759525,0.646313885,DB0140910020100_,0.436470004,0.247065012,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,tiotropium,DB01409
,77241,DB01076,10073317,43,25704,31,25552,0.20052357,1.378880332,0.848583589,2.264400463,0.349659151,DB0107610073317_,1.050796454,0.321271816,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,77276,DB01240,10035598,106,5645,35,1541,0.351316231,0.826770726,0.556810267,1.254148519,0.521034002,DB0124010035598_,0.651939976,-0.190227858,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,77277,DB00028,10011906,128,13330,111,5504,2.65255467406382e-08,0.476149118,0.365633927,0.620891488,5.4195413608836e-07,DB0002810011906_,14.42808446,-0.7420242,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,77284,DB00759,10037844,78,916,8,198,0.052382437,2.106408421,0.996205055,5.132645822,0.129484399,DB0075910037844_,2.044194878,0.744984327,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,tetracycline,DB00759
,77285,DB08880,10035664,49,3289,8,801,0.398899766,1.491537666,0.696909793,3.661577658,0.568777473,DB0888010035664_,0.564266005,0.399807579,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,teriflunomide,DB08880
,77287,DB00264,10029883,30,29577,20,24872,0.478706155,1.261378907,0.692832983,2.344082493,0.643950424,DB0026410029883_,0.440133537,0.232205493,NA,10029883,Obesity,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,77290,DB00169,10017853,82,38609,28,18147,0.152771455,1.376515709,0.886232017,2.197106234,0.287825517,DB0016910017853_,1.245400828,0.319555458,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,77292,DB00563,10017853,58,46588,17,15331,0.789073073,1.122727125,0.644530076,2.057361071,0.885694655,DB0056310017853_,0.121383021,0.115760659,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,77296,DB00996,10017853,66,38887,20,22405,0.009825587,1.901296579,1.137900981,3.312046499,0.03507375,DB0099610017853_,3.35030228,0.642536063,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,77297,DB01076,10017853,58,25689,37,25546,0.039521534,1.558819623,1.014215381,2.423056624,0.104699005,DB0107610017853_,2.256665668,0.443928883,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,77304,DB01181,10053762,68,505,71,849,0.007946919,1.609550451,1.115651376,2.320934842,0.029631147,DB0118110053762_,3.518929193,0.475954917,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ifosfamide,DB01181
,77305,DB00005,10016100,38,128044,29,42390,0.000992148,0.433798785,0.260514682,0.729404309,0.005466069,DB0000510016100_,5.209195548,-0.83517448,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,77311,DB08816,10074903,26,1125,55,1847,0.35260612,0.776185039,0.464346287,1.267363158,0.522375757,DB0881610074903_,0.649368109,-0.253364335,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,ticagrelor,DB08816
,77313,DB00264,10001760,393,29214,68,24824,1.16238970632422e-45,4.910748515,3.785657538,6.453637191,5.65803952420966e-43,DB0026410001760_,97.27808154,1.591426377,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,77346,DB00264,10008796,39,29568,49,24843,0.068312927,0.668741884,0.427423976,1.039932828,0.158244935,DB0026410008796_,1.843611224,-0.402357117,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,77347,DB00381,10008796,32,29328,46,22841,0.008305838,0.541797887,0.333809049,0.869651918,0.030684323,DB0038110008796_,3.484003421,-0.612862249,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,77372,DB00635,10020578,20,33033,31,23763,0.006867028,0.46411208,0.250678123,0.840849311,0.026402373,DB0063510020578_,3.634301368,-0.767629204,NA,10020578,Hyperbilirubinaemia,10019805,Hepatobiliary disorders,Hepat,prednisone,DB00635
,77374,DB00264,10023126,20,29587,30,24862,0.046775702,0.560214116,0.301451801,1.019918471,0.119033723,DB0026410023126_,2.128348443,-0.579436218,NA,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,metoprolol,DB00264
,77378,DB00381,10024690,31,29329,31,22856,0.370316455,0.779306178,0.458013521,1.325969392,0.539969935,DB0038110024690_,0.616241818,-0.249351271,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,amlodipine,DB00381
,77383,DB00512,10053762,133,4604,138,4960,0.805295373,1.038299625,0.809159719,1.331882266,0.894590507,DB0051210053762_,0.1113892,0.037584399,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,vancomycin,DB00512
,77384,DB01137,10053762,173,7599,129,5464,0.768210187,0.964279505,0.761135831,1.224224343,0.872826504,DB0113710053762_,0.136018478,-0.036374083,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,levofloxacin,DB01137
,77396,DB00451,10072268,75,47196,31,15388,0.260501999,0.788820785,0.512435656,1.241140964,0.421969251,DB0045110072268_,0.862822833,-0.237216126,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,levothyroxine,DB00451
,77409,DB00193,10005483,61,19259,40,8662,0.067261568,0.685893412,0.452524054,1.049929554,0.156464473,DB0019310005483_,1.854926302,-0.37703304,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,tramadol,DB00193
,77411,DB00497,10005483,72,19195,75,16300,0.245577972,0.815219778,0.581244999,1.142673452,0.404449398,DB0049710005483_,0.905228647,-0.204297535,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,oxycodone,DB00497
,77412,DB00321,10007515,116,7331,55,2795,0.196068459,0.804100566,0.57666941,1.132970509,0.344346336,DB0032110007515_,1.066107338,-0.218030936,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,amitriptyline,DB00321
,77413,DB00476,10007515,77,17180,47,6130,0.005496272,0.584576898,0.400986792,0.860130877,0.022063149,DB0047610007515_,3.813846519,-0.536866945,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,duloxetine,DB00476
,77415,DB00497,10007515,365,18902,270,16105,0.084066237,1.151808236,0.979987663,1.355108707,0.185173975,DB0049710007515_,1.686459489,0.141333087,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,oxycodone,DB00497
,77418,DB00476,10012218,35,17222,20,6157,0.093784933,0.625652753,0.3510159,1.144712727,0.201408306,DB0047610012218_,1.602421059,-0.468959769,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,77420,DB00497,10012218,85,19182,76,16299,0.751903264,0.950301617,0.6886471,1.313470066,0.860023815,DB0049710012218_,0.150795198,-0.050975853,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,77421,DB00813,10012218,62,10510,70,10098,0.382863174,0.851001295,0.594015615,1.216674088,0.552973159,DB0081310012218_,0.592445816,-0.161341629,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,fentanyl,DB00813
,77422,DB00193,10019303,89,19231,29,8673,0.13552622,1.384103769,0.900414116,2.185292066,0.263484223,DB0019310019303_,1.333761789,0.325052832,NA,10019303,Heart rate increased,10022891,Investigations,Inv,tramadol,DB00193
,77425,DB00193,10020772,235,19085,95,8607,0.402226728,1.115580185,0.874144987,1.433137153,0.572022947,DB0019310020772_,0.558576171,0.109374615,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,tramadol,DB00193
,77426,DB00490,10020772,48,4022,22,1554,0.504365224,0.843047866,0.49720669,1.471735851,0.665390872,DB0049010020772_,0.407380634,-0.170731542,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,buspirone,DB00490
,77427,DB00193,10021015,69,19251,25,8677,0.373953794,1.243980392,0.776455245,2.053637699,0.543765413,DB0019310021015_,0.609237352,0.218316232,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,tramadol,DB00193
,77429,DB00193,10044565,199,19121,75,8627,0.190220693,1.197106579,0.912296698,1.584904534,0.33683036,DB0019310044565_,1.088175858,0.179907461,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,77430,DB00497,10044565,175,19092,141,16234,0.650493375,1.055353891,0.839690787,1.328291311,0.785042166,DB0049710044565_,0.242017848,0.053876152,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,77440,DB00497,10061284,43,19224,27,16348,0.231497177,1.354319618,0.817589736,2.280281197,0.38774634,DB0049710061284_,0.947403917,0.303299201,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,77443,DB08910,10043554,67,16677,87,17401,0.196198682,0.803554478,0.574987656,1.118697721,0.344459965,DB0891010043554_,1.065777408,-0.218710295,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,pomalidomide,DB08910
,77446,DB00668,10019303,91,10000,36,4267,0.770496388,1.078596169,0.724447511,1.636676166,0.874236414,DB0066810019303_,0.134404443,0.075660352,NA,10019303,Heart rate increased,10022891,Investigations,Inv,epinephrine,DB00668
,77455,DB00722,10036790,81,25322,63,25969,0.112570316,1.318553787,0.936501654,1.863729337,0.229934394,DB0072210036790_,1.469961256,0.27653552,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,77460,DB00722,10038687,35,25368,52,25980,0.106948224,0.689322734,0.435650162,1.078911095,0.221549754,DB0072210038687_,1.50710809,-0.372045708,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,77463,DB00722,10042604,27,25376,32,26000,0.604320713,0.864501034,0.498104706,1.489949588,0.747737894,DB0072210042604_,0.290702771,-0.145602777,NA,10042604,Supraventricular tachycardia,10007541,Cardiac disorders,Card,lisinopril,DB00722
,77470,DB00563,10065553,52,46594,75,15273,2.26865136161825e-16,0.22728978,0.156345125,0.328207921,1.62927598470316e-14,DB0056310065553_,31.74805557,-1.481529511,male,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,methotrexate,DB00563
,77471,DB00982,10002855,108,3256,70,2031,0.814523309,0.962368278,0.702040546,1.32637099,0.900515044,DB0098210002855_,0.104788409,-0.038358076,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,isotretinoin,DB00982
,77484,DB00338,10064684,55,33619,6,22266,2.70000094732049e-07,6.070188843,2.617354206,17.2577614,4.44253676997302e-06,DB0033810064684_,12.324285,1.803389715,female,10064684,Device dislocation,10077536,Product issues,Prod,omeprazole,DB00338
,77494,DB00480,10024690,34,67394,38,67624,0.723905998,0.897791434,0.548166669,1.465028659,0.837715468,DB0048010024690_,0.177076773,-0.107817494,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,lenalidomide,DB00480
,77496,DB01234,10061016,62,31563,53,32835,0.305605716,1.216949111,0.829426797,1.791034967,0.472381431,DB0123410061016_,0.749968503,0.196346998,NA,10061016,Blood test abnormal,10022891,Investigations,Inv,dexamethasone,DB01234
,77498,DB00451,10049438,109,47162,35,15384,1,1.015867322,0.688125199,1.533053593,1,DB0045110049438_,0,0.015742752,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,77507,DB00722,10005728,62,25341,37,25995,0.00878906,1.718891762,1.125555638,2.658126218,0.032101778,DB0072210005728_,3.438843862,0.541679759,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,lisinopril,DB00722
,77509,DB00203,10024264,64,13814,60,8878,0.042010394,0.68555703,0.473901204,0.992812946,0.109716649,DB0020310024264_,2.209854156,-0.377523589,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,77510,DB00203,10040984,46,13832,16,8922,0.036367167,1.854399687,1.029707015,3.511347494,0.098291851,DB0020310040984_,2.319814157,0.617561025,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,sildenafil,DB00203
,77511,DB00374,10040984,40,17676,16,5708,0.440336252,0.807308834,0.441707376,1.545484347,0.608705902,DB0037410040984_,0.496420047,-0.21404899,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,treprostinil,DB00374
,77512,DB00203,10068319,205,13673,52,8886,7.64824390159032e-11,2.561975952,1.879076353,3.547862344,2.54634694051047e-09,DB0020310068319_,19.78860608,0.940778817,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,77517,DB00068,10053425,38,2196,13,652,0.617875789,0.867939831,0.44896476,1.786854005,0.758848011,DB0006810053425_,0.275953771,-0.141632886,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,interferon beta-1b,DB00068
,77522,DB01118,10061924,73,2990,133,4576,0.248226477,0.840051232,0.620167842,1.130397161,0.40761123,DB0111810061924_,0.897441427,-0.174292398,NA,10061924,Pulmonary toxicity,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,77524,DB00559,10037324,40,9619,14,3292,1,0.977827456,0.519990783,1.948415281,1,DB0055910037324_,0,-0.02242205,NA,10037324,Pulmonary arterial pressure increased,10022891,Investigations,Inv,bosentan,DB00559
,77526,DB08931,10037324,65,6512,16,2430,0.166504539,1.515819593,0.865023444,2.812809723,0.306139605,DB0893110037324_,1.183714055,0.415956278,NA,10037324,Pulmonary arterial pressure increased,10022891,Investigations,Inv,riociguat,DB08931
,77527,DB06228,10037437,48,15864,33,16043,0.09525366,1.470932367,0.924353424,2.366704166,0.203605958,DB0622810037437_,1.591568733,0.385896463,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,77528,DB08931,10037437,42,6535,21,2425,0.258137179,0.742183815,0.428728298,1.322122797,0.419068355,DB0893110037437_,0.869721233,-0.298158337,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,77529,DB08931,10042772,253,6324,100,2346,0.625110589,0.938550776,0.737878752,1.201167734,0.764732004,DB0893110042772_,0.268229828,-0.063418321,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,77533,DB00374,10018836,71,17645,25,5699,0.721198773,0.917259962,0.573576941,1.512093972,0.835557454,DB0037410018836_,0.179656167,-0.086364355,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,77534,DB06403,10018836,46,21425,17,6644,0.552995638,0.839089907,0.471603355,1.562395233,0.706669762,DB0640310018836_,0.347191819,-0.175437419,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,77535,DB08931,10018836,58,6519,20,2426,0.898235708,1.079205001,0.637878896,1.898684361,0.956353692,DB0893110018836_,0.044627464,0.07622466,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,77544,DB00374,10047571,79,17637,22,5702,0.642354977,1.160922742,0.715408962,1.958099067,0.778832076,DB0037410047571_,0.24995982,0.149215156,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,treprostinil,DB00374
,77545,DB00682,10047571,98,19361,38,16326,2.9100622804501e-05,2.174579954,1.48014739,3.25383407,0.000276141,DB0068210047571_,8.194599868,0.776835521,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,warfarin,DB00682
,77546,DB06403,10058080,55,21416,13,6648,0.474852225,1.313301905,0.707801248,2.622223315,0.640497571,DB0640310058080_,0.445509949,0.272544504,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,77549,DB00009,10053762,53,1298,46,1505,0.182446336,1.335775322,0.876271156,2.042822001,0.326988693,DB0000910053762_,1.117829688,0.289511889,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,alteplase,DB00009
,77553,DB01248,10015150,97,2603,25,1349,0.001295804,2.010498916,1.277096637,3.274287842,0.006809319,DB0124810015150_,4.989463118,0.698382908,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,docetaxel,DB01248
,77563,DB01234,10073133,78,31547,122,32766,0.004566527,0.664056167,0.493057353,0.889893606,0.018992273,DB0123410073133_,3.963723066,-0.409388545,NA,10073133,Plasma cell myeloma recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,77568,DB00338,10001480,63,33611,68,22204,0.005468281,0.612066582,0.427275728,0.875635308,0.021973083,DB0033810001480_,3.817937093,-0.490914208,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,77570,DB00999,10001480,51,21379,33,12206,0.571993943,0.882359769,0.558186497,1.412266433,0.722083461,DB0099910001480_,0.32561455,-0.125155405,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,77571,DB01076,10001480,55,25692,62,25521,0.517924982,0.881195165,0.601311474,1.28836776,0.677380677,DB0107610001480_,0.389521865,-0.126476151,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,77579,DB00338,10025197,72,33602,36,22236,0.200634327,1.323485627,0.874993722,2.033907213,0.349747871,DB0033810025197_,1.050542752,0.280268883,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,omeprazole,DB00338
,77592,DB00695,10002424,54,27995,33,20495,0.448152909,1.197961025,0.762568781,1.90789463,0.615867581,DB0069510002424_,0.484723305,0.180620966,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,77612,DB00295,10022687,25,14638,33,9569,0.009997198,0.495240541,0.282155012,0.859182752,0.035558368,DB0029510022687_,3.336579768,-0.702711692,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,77619,DB01222,10022687,32,9242,23,5382,0.484264594,0.810237152,0.458988951,1.451602033,0.648424383,DB0122210022687_,0.433209885,-0.210428294,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,77622,DB00567,10047700,132,4387,38,2043,0.009329843,1.617566884,1.11526058,2.395259014,0.033666192,DB0056710047700_,3.391261148,0.480923097,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cephalexin,DB00567
,77645,DB00188,10023232,82,7804,66,8762,0.047157375,1.394903778,0.99490789,1.962055348,0.119755723,DB0018810023232_,2.122301252,0.332825437,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,bortezomib,DB00188
,77646,DB00480,10023232,619,66809,495,67167,0.000167002,1.257200926,1.114715552,1.418491564,0.001237741,DB0048010023232_,6.694467076,0.228887763,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,77647,DB00787,10023232,157,16843,100,17148,0.00026646,1.598398185,1.234837363,2.076934568,0.001831804,DB0078710023232_,6.302454158,0.469001994,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,77648,DB00927,10023232,55,7442,26,4990,0.171911729,1.418365945,0.87307089,2.359745935,0.313328378,DB0092710023232_,1.160503506,0.349505466,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,famotidine,DB00927
,77649,DB01234,10023232,285,31340,235,32653,0.008217131,1.263567097,1.058676192,1.509327098,0.030437891,DB0123410023232_,3.492067017,0.23393875,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,77650,DB00188,10043607,118,7768,157,8671,0.161383095,0.838971525,0.653741678,1.074314499,0.29931816,DB0018810043607_,1.206248191,-0.175578513,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,bortezomib,DB00188
,77651,DB00787,10043607,294,16706,379,16869,0.001832574,0.783301895,0.669287954,0.916025371,0.009055215,DB0078710043607_,4.70441446,-0.244237095,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,acyclovir,DB00787
,77652,DB00787,10050584,103,16897,67,17181,0.00437672,1.563122304,1.13726832,2.160786231,0.018364127,DB0078710050584_,3.997356116,0.446685298,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,77655,DB01202,10044565,86,6628,83,5635,0.437453892,0.880920521,0.642497304,1.208370038,0.605884474,DB0120210044565_,0.501065948,-0.126787872,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,77656,DB00582,10013710,95,1035,135,1439,0.889092734,0.978392155,0.735245112,1.297983611,0.953955749,DB0058210013710_,0.047137994,-0.021844713,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,voriconazole,DB00582
,77661,DB08901,10020772,31,476,27,553,0.343809733,1.333513792,0.758096008,2.358836825,0.51306,DB0890110020772_,0.667362482,0.287817407,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ponatinib,DB08901
,77667,DB01273,10013709,120,1920,80,1195,0.653308394,0.933613857,0.690947446,1.266877086,0.787463251,DB0127310013709_,0.238938574,-0.068692356,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,varenicline,DB01273
,77672,DB05259,10061822,156,11114,23,2705,0.022514902,1.650726656,1.058758516,2.686476395,0.067758667,DB0525910061822_,2.691802903,0.501215588,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,77673,DB00736,10022052,41,10550,12,5541,0.081892203,1.794419641,0.924302951,3.753659941,0.181537288,DB0073610022052_,1.706294205,0.58468165,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,77677,DB00047,10022086,170,9115,108,8410,0.00246077,1.452292111,1.13221472,1.86958362,0.01152246,DB0004710022086_,4.463457111,0.373143074,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,77678,DB00736,10022086,88,10503,25,5528,0.005270434,1.852602812,1.175111213,3.01940832,0.021329232,DB0073610022086_,3.84767677,0.616591576,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,77679,DB01097,10022086,165,6100,24,1479,0.019392669,1.666787614,1.077355222,2.685904862,0.060338103,DB0109710022086_,2.80779148,0.51089819,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,77680,DB01306,10022086,42,4166,20,3846,0.014945519,1.938534288,1.110747414,3.492043263,0.049172983,DB0130610022086_,3.012410931,0.661932166,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,77682,DB00047,10022093,41,9244,11,8507,0.00012288,3.429695521,1.730028197,7.404095242,0.000951233,DB0004710022093_,6.957751109,1.232471488,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,77684,DB01097,10022093,103,6162,7,1496,0.00021154,3.5719535,1.668037455,9.124799829,0.001510342,DB0109710022093_,6.495419074,1.273112645,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,77694,DB00203,10028997,39,13839,26,8912,0.899269164,0.965944877,0.572855183,1.653926564,0.956490275,DB0020310028997_,0.044484657,-0.034648509,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sildenafil,DB00203
,77695,DB08931,10003658,139,6438,50,2396,0.869058417,1.034640773,0.74104391,1.46476004,0.941754638,DB0893110003658_,0.060010508,0.034054287,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,riociguat,DB08931
,77696,DB08932,10003658,374,19069,146,6451,0.153774768,0.866622322,0.712286561,1.058853647,0.289176876,DB0893210003658_,1.240716751,-0.143152012,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,macitentan,DB08932
,77697,DB00186,10008190,112,16789,66,9942,1,1.004900256,0.734053191,1.385056466,1,DB0018610008190_,0,0.004888289,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,77703,DB00863,10008190,84,10589,62,5778,0.081723984,0.739320696,0.525275417,1.045367732,0.181260224,DB0086310008190_,1.707821581,-0.302023492,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,77708,DB00316,10013663,159,65315,169,36784,1.26807541533661e-08,0.529840531,0.423809719,0.662158866,2.7869032016825e-07,DB0031610013663_,15.09316464,-0.635179203,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,77709,DB00497,10013663,167,19100,254,16121,2.86509955452144e-09,0.554950376,0.453214489,0.678051569,7.27273218644096e-08,DB0049710013663_,16.43654871,-0.588876581,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,77713,DB00497,10042458,92,19175,76,16299,0.876922521,1.028966355,0.750527769,1.414231414,0.947522597,DB0049710042458_,0.053904493,0.02855476,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,77717,DB00497,10066169,43,19224,72,16303,0.000346058,0.506492377,0.338622115,0.749597312,0.002274036,DB0049710066169_,6.086199027,-0.680246005,NA,10066169,Substance abuse,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,77718,DB00497,10074903,202,19065,180,16195,0.642727127,0.953264119,0.775039956,1.173319688,0.779139535,DB0049710074903_,0.249565129,-0.047863269,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,77722,DB00374,10020937,100,17616,22,5702,0.112680635,1.471233364,0.919274271,2.454835199,0.230115025,DB0037410020937_,1.469175985,0.386101072,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,77723,DB00537,10020751,93,7464,40,4258,0.147049642,1.326316092,0.904384207,1.976443217,0.279823343,DB0053710020751_,1.273596792,0.282405244,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ciprofloxacin,DB00537
,77724,DB00480,10009944,41,67387,38,67624,0.737070842,1.082713876,0.679140051,1.730086797,0.848337474,DB0048010009944_,0.164476757,0.079470738,NA,10009944,Colon cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,77737,DB08908,10039203,51,10622,29,3250,0.011259309,0.538128148,0.33405605,0.882058716,0.039126321,DB0890810039203_,3.24095988,-0.619658553,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,dimethyl fumarate,DB08908
,77757,DB08904,10020751,168,11442,21,3538,1.95353858775082e-05,2.473689923,1.563813799,4.10767284,0.000195614,DB0890410020751_,8.539365538,0.905710932,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,certolizumab pegol,DB08904
,77759,DB13867,10040753,124,4426,47,2507,0.019307839,1.494319809,1.055926693,2.145501877,0.060141796,DB1386710040753_,2.811050244,0.401671126,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,fluticasone,DB13867
,77766,DB06285,10028810,71,8779,8,1098,1,1.110011378,0.531915478,2.677662053,1,DB0628510028810_,0,0.104370266,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,teriparatide,DB06285
,77767,DB06285,10035664,142,8708,42,1064,4.28353479880394e-06,0.413169436,0.289065276,0.601325827,5.15416398198954e-05,DB0628510035664_,9.873120537,-0.883897513,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,teriparatide,DB06285
,77770,DB01076,10022004,118,25629,80,25503,0.008326937,1.467730387,1.095095984,1.975763067,0.030738508,DB0107610022004_,3.482239066,0.383717253,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,77777,DB00820,10028810,422,11493,116,5700,6.24774358160394e-09,1.804192121,1.46191913,2.240983665,1.47284251159157e-07,DB0082010028810_,15.73090144,0.590112913,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,tadalafil,DB00820
,77778,DB00559,10046306,82,9577,30,3276,0.744521816,0.934989144,0.607345132,1.474744995,0.854143649,DB0055910046306_,0.157655892,-0.06722036,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,bosentan,DB00559
,77779,DB00820,10046306,140,11775,33,5783,8.26173175745341e-05,2.08348657,1.415317708,3.148248667,0.000677777,DB0082010046306_,7.296692838,0.734042726,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,tadalafil,DB00820
,77801,DB01233,10013950,41,3380,20,1706,1,1.034698556,0.590343214,1.870333998,1,DB0123310013950_,0,0.034110134,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,metoclopramide,DB01233
,77805,DB01233,10022437,52,3369,18,1708,0.201979723,1.464494069,0.839567322,2.66870926,0.351382422,DB0123310022437_,1.045880127,0.381509837,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,metoclopramide,DB01233
,77823,DB00203,10007617,36,13842,42,8896,0.010167324,0.550903632,0.342638013,0.881623595,0.036036691,DB0020310007617_,3.323217673,-0.596195381,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,sildenafil,DB00203
,77826,DB00480,10005654,131,67297,68,67594,6.77037743705739e-06,1.934951835,1.432584115,2.634012483,7.71941216433422e-05,DB0048010005654_,9.469187248,0.660082435,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,77841,DB00480,10013911,317,67111,294,67368,0.330838375,1.082332229,0.920276464,1.273338646,0.499532841,DB0048010013911_,0.694081936,0.079118184,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,77845,DB00470,10016256,76,843,62,891,0.157122782,1.295418586,0.901356582,1.867539297,0.293624865,DB0047010016256_,1.225452297,0.258833875,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dronabinol,DB00470
,77846,DB00338,10019304,59,33615,25,22247,0.073655192,1.561876283,0.962832837,2.603591072,0.167592341,DB0033810019304_,1.786220791,0.445887844,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,omeprazole,DB00338
,77848,DB00480,10019304,82,67346,79,67583,0.813371071,1.041639489,0.755193489,1.437438026,0.899775248,DB0048010019304_,0.105610271,0.040795903,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,lenalidomide,DB00480
,77852,DB01076,10019304,39,25708,47,25536,0.389484286,0.824239942,0.524777219,1.288111871,0.559382874,DB0107610019304_,0.580921114,-0.193293599,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,atorvastatin,DB01076
,77853,DB00470,10028813,104,815,74,879,0.00928496,1.515417852,1.096337949,2.102976911,0.033537884,DB0047010028813_,3.395079609,0.415691211,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dronabinol,DB00470
,77854,DB00470,10033371,33,886,27,926,0.361686473,1.277230582,0.737952555,2.228017399,0.531467719,DB0047010033371_,0.632112818,0.244694126,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,dronabinol,DB00470
,77855,DB00661,10033371,118,3410,24,1571,0.00014386,2.26482312,1.444131193,3.689832398,0.00108832,DB0066110033371_,6.823120325,0.817496663,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,verapamil,DB00661
,77857,DB00661,10037844,66,3462,24,1571,0.421526358,1.247824918,0.768189599,2.090704592,0.590608758,DB0066110037844_,0.52660148,0.22140197,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,verapamil,DB00661
,77858,DB00758,10037844,163,8137,197,9877,1,1.004343135,0.809325249,1.245004007,1,DB0075810037844_,0,0.004333731,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,clopidogrel,DB00758
,77859,DB00758,10047700,240,8060,158,9916,1.05543667994077e-09,1.868677317,1.518959395,2.304098179,2.92176441624466e-08,DB0075810047700_,17.34849306,0.625230863,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,77862,DB00959,10052904,77,8001,22,4980,0.000823904,2.178356618,1.339627377,3.68052624,0.004692082,DB0095910052904_,5.361878801,0.778570748,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,methylprednisolone,DB00959
,77872,DB00715,10040108,49,4794,48,2239,0.000396493,0.476815109,0.312545976,0.727736475,0.002543456,DB0071510040108_,5.974231384,-0.740626476,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,paroxetine,DB00715
,77874,DB00484,10019211,83,2424,40,1740,0.041234336,1.489345479,1.003962836,2.241490781,0.108178913,DB0048410019211_,2.22396882,0.398336748,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,brimonidine,DB00484
,77879,DB00331,10005839,42,24904,38,20714,0.736765829,0.91930907,0.578298648,1.465675401,0.848079282,DB0033110005839_,0.164781155,-0.084132902,NA,10005839,Blood triglycerides increased,10022891,Investigations,Inv,metformin,DB00331
,77887,DB00542,10047895,31,1655,36,1388,0.215216017,0.722270957,0.429593766,1.208007059,0.36764496,DB0054210047895_,1.00063759,-0.325354924,NA,10047895,Weight decreased,10022891,Investigations,Inv,benazepril,DB00542
,77888,DB01039,10047895,66,2907,85,2966,0.162245652,0.792261992,0.563091436,1.110569313,0.300389304,DB0103910047895_,1.202675965,-0.232863144,NA,10047895,Weight decreased,10022891,Investigations,Inv,fenofibrate,DB01039
,77889,DB06655,10047895,75,3613,58,2061,0.100571596,0.737699601,0.514295125,1.062596156,0.211719077,DB0665510047895_,1.552494993,-0.304218582,NA,10047895,Weight decreased,10022891,Investigations,Inv,liraglutide,DB06655
,77892,DB00381,10048592,45,29315,26,22861,0.233591613,1.349713399,0.814685627,2.279596923,0.390272083,DB0038110048592_,0.940911135,0.299892273,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,77894,DB00695,10048592,43,28006,25,20503,0.391462163,1.259193643,0.751629992,2.152062021,0.561325586,DB0069510048592_,0.577454175,0.23047155,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,77907,DB00005,10063829,507,127575,192,42227,0.114584232,0.87405868,0.738593168,1.037810866,0.233014538,DB0000510063829_,1.45665443,-0.134607766,NA,10063829,Device malfunction,10077536,Product issues,Prod,etanercept,DB00005
,77908,DB00158,10063829,35,16780,19,8085,0.664893753,0.887579542,0.493639049,1.643540612,0.796043285,DB0015810063829_,0.228101716,-0.119257137,NA,10063829,Device malfunction,10077536,Product issues,Prod,folic acid,DB00158
,77910,DB00563,10063829,82,46564,26,15322,1,1.037801158,0.660253768,1.681990449,1,DB0056310063829_,0,0.037104203,NA,10063829,Device malfunction,10077536,Product issues,Prod,methotrexate,DB00563
,77937,DB00982,10027951,61,3303,60,2041,0.013699262,0.6283009,0.430676357,0.916839451,0.045754272,DB0098210027951_,3.084470116,-0.464736087,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,isotretinoin,DB00982
,77944,DB00104,10016256,75,1406,46,1031,0.396091709,1.195492076,0.809573472,1.781494799,0.565722312,DB0010410016256_,0.569651936,0.17855788,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,octreotide,DB00104
,77945,DB00104,10016825,32,1449,20,1057,0.671104016,1.16706139,0.643262256,2.166062878,0.800438343,DB0010410016825_,0.222595773,0.154488957,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,octreotide,DB00104
,77950,DB00104,10047895,41,1440,34,1043,0.635203267,0.873476041,0.536761448,1.429682317,0.773299888,DB0010410047895_,0.257088353,-0.135274578,NA,10047895,Weight decreased,10022891,Investigations,Inv,octreotide,DB00104
,77952,DB01261,10010264,42,3739,23,3280,0.079933206,1.60180771,0.939223603,2.796715972,0.178317269,DB0126110010264_,1.724190907,0.47113281,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,77957,DB09140,10022611,47,3694,16,1782,0.278962584,1.416982496,0.786396668,2.685227247,0.442812459,DB0914010022611_,0.814608941,0.348529608,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,77958,DB00736,10020937,129,10462,45,5508,0.019679834,1.509197357,1.065374083,2.172441008,0.06103291,DB0073610020937_,2.796342051,0.411577958,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,77961,DB00736,10033433,47,10544,14,5539,0.059816666,1.763526059,0.953477971,3.471562045,0.143155883,DB0073610033433_,1.943821149,0.567315247,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,77962,DB01234,10033433,45,31580,40,32848,0.515317205,1.17016679,0.746999764,1.838989733,0.675145805,DB0123410033433_,0.392826603,0.157146294,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,77963,DB00222,10000081,41,3165,35,3093,0.566492578,1.144754832,0.709184014,1.856901258,0.717844931,DB0022210000081_,0.331501707,0.135190493,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,glimepiride,DB00222
,77964,DB00697,10000081,90,6006,22,1784,0.496349515,1.215115866,0.753042601,2.04101516,0.658567276,DB0069710000081_,0.417688598,0.194839435,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,tizanidine,DB00697
,77967,DB00476,10006002,64,17193,21,6156,0.805769841,1.091203447,0.656961643,1.882829999,0.894899878,DB0047610006002_,0.111043435,0.087281167,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,77969,DB00273,10017577,126,8355,39,2154,0.331390261,0.832933847,0.57544574,1.229583048,0.500165043,DB0027310017577_,0.692817149,-0.182801055,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,77970,DB00254,10019211,263,5672,80,3308,1.64895105512623e-07,1.917197514,1.481492246,2.503647969,2.85618968593034e-06,DB0025410019211_,12.7660221,0.650864491,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,doxycycline,DB00254
,77981,DB00814,10053425,87,8200,11,3404,2.85736428689076e-05,3.282672605,1.74436801,6.828729806,0.000271827,DB0081410053425_,8.210344455,1.188657909,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,77983,DB00390,10013709,107,4038,102,3199,0.203644014,0.831082298,0.625092843,1.105472354,0.353434567,DB0039010013709_,1.040056911,-0.185026454,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,77984,DB05332,10013709,58,971,48,739,0.687267203,0.919670728,0.60869136,1.394900539,0.811427859,DB0533210013709_,0.208959794,-0.083739577,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,romiplostim,DB05332
,77985,DB05332,10003239,54,975,33,754,0.319713459,1.265292117,0.796563564,2.03641112,0.487866278,DB0533210003239_,0.71771393,0.235303018,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,romiplostim,DB05332
,77986,DB05332,10019211,98,931,43,744,0.001387775,1.820719134,1.242136113,2.705769212,0.007211161,DB0533210019211_,4.932125311,0.599231551,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,romiplostim,DB05332
,77990,DB00734,10005780,74,3976,52,4850,0.002795284,1.735763472,1.197967487,2.531109894,0.012758122,DB0073410005780_,4.361587157,0.551447358,NA,10005780,Blood prolactin increased,10022891,Investigations,Inv,risperidone,DB00734
,77993,DB00230,10029223,186,19488,88,8563,0.59804561,0.928733316,0.715945408,1.212467637,0.742999711,DB0023010029223_,0.297059623,-0.073933647,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,77995,DB00497,10069327,59,19208,49,16326,0.923283616,1.023421235,0.688367505,1.527512994,0.966507093,DB0049710069327_,0.034066642,0.023151166,NA,10069327,Product quality issue,10077536,Product issues,Prod,oxycodone,DB00497
,77997,DB00537,10000081,180,7377,76,4222,0.029902448,1.355459854,1.028155052,1.801392544,0.08450552,DB0053710000081_,2.470938419,0.304140773,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ciprofloxacin,DB00537
,77999,DB00787,10000081,153,16847,111,17137,0.007772485,1.402085134,1.089862317,1.808382493,0.029100458,DB0078710000081_,3.537001372,0.33796051,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,78000,DB08910,10000081,50,16694,51,17437,0.920906919,1.024030524,0.678821151,1.544112154,0.964941435,DB0891010000081_,0.035687869,0.023746334,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,78001,DB11365,10000081,56,1589,23,1525,0.000548606,2.336287087,1.406203543,3.999168123,0.003331819,DB1136510000081_,5.704236745,0.848562954,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,sennosides,DB11365
,78002,DB00540,10010774,43,2440,19,1072,1,0.994306989,0.564020629,1.815625571,1,DB0054010010774_,0,-0.005709278,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,nortriptyline,DB00540
,78003,DB00787,10010774,463,16537,369,16879,0.000445563,1.280678661,1.112640117,1.474938446,0.002806189,DB0078710010774_,5.87592779,0.247390141,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,78004,DB00540,10013968,86,2397,27,1064,0.145653727,1.413759221,0.901937627,2.280824863,0.27797199,DB0054010013968_,1.280234925,0.346252271,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nortriptyline,DB00540
,78005,DB00540,10047700,65,2418,16,1075,0.037372329,1.805852231,1.027128496,3.360253264,0.100324941,DB0054010047700_,2.299340952,0.59103263,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,nortriptyline,DB00540
,78006,DB00787,10047700,415,16585,212,17036,3.85031847055031e-17,2.010725854,1.697579833,2.38727636,2.99458606852011e-15,DB0078710047700_,33.44197038,0.698495778,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,78007,DB08910,10047700,175,16569,109,17379,1.65885822287627e-05,1.683953669,1.316925523,2.161258784,0.000169332,DB0891010047700_,8.683647017,0.521144403,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,78008,DB11365,10047700,95,1550,43,1505,3.637836096159e-05,2.144659975,1.469585767,3.173819277,0.000336159,DB1136510047700_,7.99792531,0.76298102,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sennosides,DB11365
,78010,DB00316,10061105,42,65432,36,36917,0.076227012,0.658271307,0.411604675,1.057628241,0.171837651,DB0031610061105_,1.761205137,-0.418138111,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,78011,DB00338,10061105,35,33639,26,22246,0.69526083,0.890236557,0.520609083,1.540452021,0.816560818,DB0033810061105_,0.202653883,-0.116268057,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,omeprazole,DB00338
,78025,DB00331,10038776,48,24898,25,20727,0.059894478,1.598335,0.965779959,2.705963975,0.14328992,DB0033110038776_,1.942885288,0.468962462,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,78026,DB00005,10028997,168,127914,77,42342,0.021613932,0.722225575,0.548191451,0.958819623,0.065751081,DB0000510028997_,2.721879168,-0.325417759,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,etanercept,DB00005
,78029,DB00512,10013687,16,4721,42,5056,0.002152071,0.408044427,0.213865578,0.742307521,0.010331908,DB0051210013687_,4.572518306,-0.89637922,NA,10013687,Drug eruption,10040785,Skin and subcutaneous tissue disorders,Skin,vancomycin,DB00512
,78031,DB00788,10008479,106,9250,49,5012,0.397796225,1.172106296,0.826335297,1.682921009,0.567463029,DB0078810008479_,0.56657968,0.158802383,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,78035,DB00065,10053762,605,8859,442,4515,5.00313042602139e-08,0.697591661,0.612812207,0.794612086,9.68389420088161e-07,DB0006510053762_,13.84763154,-0.360121361,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,infliximab,DB00065
,78036,DB00065,10066901,260,9204,66,4891,1.69567227248245e-08,2.093295782,1.588334047,2.79213576,3.6089672617167e-07,DB0006510066901_,14.834674,0.738739753,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,78038,DB05679,10019211,272,6659,126,4783,5.14809812063124e-05,1.550506932,1.246450003,1.937185651,0.000452874,DB0567910019211_,7.699896868,0.43858193,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ustekinumab,DB05679
,78039,DB05679,10065154,116,6815,73,4836,0.457028579,1.127627721,0.832115452,1.536381363,0.624343652,DB0567910065154_,0.471054338,0.120116064,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,ustekinumab,DB05679
,78040,DB00005,10017543,41,128041,18,42401,0.365310041,0.754291555,0.423720315,1.395105909,0.534895381,DB0000510017543_,0.6256841,-0.281976308,NA,10017543,Fungal skin infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,78056,DB01109,10003239,55,4357,30,4240,0.011792959,1.783976558,1.120904696,2.889682814,0.040607577,DB0110910003239_,3.203800602,0.578844894,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,heparin,DB01109
,78057,DB01225,10003239,59,4985,43,4597,0.273234188,1.265265595,0.83785184,1.92442288,0.436208852,DB0122510003239_,0.829634132,0.235282057,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,enoxaparin,DB01225
,78058,DB01377,10003239,94,3702,37,2633,0.002201703,1.806764623,1.218440209,2.728886096,0.010521184,DB0137710003239_,4.554364517,0.591537745,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium oxide,DB01377
,78060,DB00188,10037660,179,7707,236,8592,0.100334845,0.845579825,0.690605081,1.033888006,0.211330695,DB0018810037660_,1.554331096,-0.167732703,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,78062,DB01377,10037660,123,3673,79,2591,0.561594752,1.098318176,0.817331978,1.482956085,0.713983118,DB0137710037660_,0.336895961,0.093780078,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,78063,DB00177,10001760,75,4725,9,2841,7.37185189076876e-08,5.009574764,2.497834567,11.40147555,1.37348720648771e-06,DB0017710001760_,13.49815765,1.611351034,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,valsartan,DB00177
,78066,DB00641,10001551,32,14092,29,12446,1,0.97455577,0.570647472,1.670775639,1,DB0064110001551_,0,-0.025773533,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,simvastatin,DB00641
,78068,DB01016,10005557,50,1051,36,1192,0.047166079,1.574895438,0.997011118,2.509656562,0.119766234,DB0101610005557_,2.122213486,0.454188882,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,glyburide,DB01016
,78076,DB11133,10033371,117,2314,32,1542,3.12606088132295e-06,2.435949864,1.625712569,3.743859558,3.92493481087049e-05,DB1113310033371_,10.14557572,0.890336768,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,78077,DB00115,10040984,72,18353,27,10445,0.074466578,1.517623768,0.962237384,2.45912892,0.168941308,DB0011510040984_,1.778203913,0.417145801,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,78084,DB00999,10007632,19,21411,34,12205,4.41191561834346e-05,0.318559655,0.171581287,0.574847808,0.000397284,DB0099910007632_,7.830859147,-1.143945522,male,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,78086,DB00641,10008479,211,13913,121,12354,0.000127988,1.548372421,1.230706693,1.955244083,0.000984459,DB0064110008479_,6.923418552,0.437204328,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,78087,DB00338,10020765,65,33609,39,22233,0.688792563,1.102550171,0.729857868,1.685146103,0.81240636,DB0033810020765_,0.207754621,0.097625834,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,78089,DB01050,10020765,39,18069,13,9358,0.188841167,1.553687513,0.811372881,3.173819352,0.33510144,DB0105010020765_,1.093321986,0.440631146,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,78093,DB00688,10018651,36,6454,70,5308,1.99031804428855e-05,0.422994906,0.274338634,0.642234368,0.000198956,DB0068810018651_,8.522426298,-0.860395142,NA,10018651,Graft versus host disease,10021428,Immune system disorders,Immun,mycophenolate mofetil,DB00688
,78097,DB00051,10022095,515,25216,88,11332,2.58378581618319e-20,2.629937096,2.091719861,3.339577024,2.7440327344798e-18,DB0005110022095_,40.43710303,0.966959928,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,78098,DB00051,10044565,86,25645,38,11382,1,1.004456033,0.677653266,1.513817693,1,DB0005110044565_,0,0.004446134,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,78099,DB01175,10014387,83,10641,10,4882,4.75487295067663e-06,3.807313486,1.968010959,8.240029063,5.6616913027649e-05,DB0117510014387_,9.779202801,1.336923819,female,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,escitalopram,DB01175
,78100,DB01175,10033295,94,10630,55,4837,0.155327104,0.777675672,0.55071113,1.107399919,0.29126256,DB0117510033295_,1.233530152,-0.251445715,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,78101,DB01175,10042464,62,10662,43,4849,0.035050764,0.655762588,0.436677455,0.992826478,0.095497211,DB0117510042464_,2.348658241,-0.421956465,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,78107,DB00864,10059866,29,6840,42,8350,0.550373568,0.842915641,0.505800074,1.387145658,0.704616791,DB0086410059866_,0.350101182,-0.170888396,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,78109,DB01115,10011906,226,3374,130,2138,0.400339229,1.101613685,0.877632426,1.387196774,0.570193261,DB0111510011906_,0.561779921,0.096776091,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,78110,DB00668,10011906,84,10007,96,4207,6.1614262185862e-11,0.367883609,0.270549873,0.499411724,2.08165923079098e-09,DB0066810011906_,19.99010055,-0.999988671,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,78113,DB13867,10011906,153,4397,129,2425,0.000607056,0.654131638,0.511314257,0.837916617,0.003633903,DB1386710011906_,5.617447948,-0.424446666,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,78114,DB00472,10007617,184,10575,45,4267,0.002431054,1.649825315,1.182681986,2.344119097,0.011406687,DB0047210007617_,4.473555533,0.500669413,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,fluoxetine,DB00472
,78123,DB06643,10013971,38,52383,15,7500,0.00251612,0.362721745,0.194796418,0.710169607,0.011719005,DB0664310013971_,4.446543434,-1.014119282,male,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,denosumab,DB06643
,78124,DB00843,10016173,162,2032,179,1994,0.310102338,0.888127928,0.707058723,1.11492797,0.477534709,DB0084310016173_,0.739118433,-0.118639484,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,donepezil,DB00843
,78125,DB01043,10016173,127,1274,118,1292,0.547410483,1.091433152,0.832409229,1.431923372,0.702075413,DB0104310016173_,0.353714455,0.087491651,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,memantine,DB01043
,78126,DB00843,10016256,127,2067,106,2067,0.200700282,1.198061805,0.911515663,1.577191853,0.349816446,DB0084310016256_,1.050346703,0.180705089,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,donepezil,DB00843
,78134,DB00451,10020765,127,47144,49,15370,0.334778626,0.844969254,0.602900325,1.200919975,0.503951579,DB0045110020765_,0.68527509,-0.168455038,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,78153,DB00927,10027175,78,7419,33,4983,0.025338999,1.587488089,1.042179666,2.466757741,0.074245185,DB0092710027175_,2.600382358,0.462152948,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,78154,DB01043,10027175,29,1372,32,1378,0.796027785,0.91025396,0.528103379,1.562898169,0.889513883,DB0104310027175_,0.117080164,-0.094031642,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,memantine,DB01043
,78155,DB06643,10027175,220,52201,21,7494,0.078797017,1.503956942,0.959022096,2.480036627,0.176308116,DB0664310027175_,1.735522157,0.408099596,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,78170,DB00843,10047895,39,2155,45,2128,0.509711505,0.85583959,0.540364376,1.350151811,0.670273753,DB0084310047895_,0.400069063,-0.155672315,NA,10047895,Weight decreased,10022891,Investigations,Inv,donepezil,DB00843
,78171,DB00927,10047895,154,7343,93,4923,0.470820814,1.110197858,0.850418944,1.455849946,0.637059873,DB0092710047895_,0.450891635,0.10453825,NA,10047895,Weight decreased,10022891,Investigations,Inv,famotidine,DB00927
,78172,DB01043,10047895,41,1360,26,1384,0.064116739,1.604473975,0.952180864,2.748491197,0.150857852,DB0104310047895_,1.891417264,0.472795962,NA,10047895,Weight decreased,10022891,Investigations,Inv,memantine,DB01043
,78174,DB00472,10061428,122,10637,59,4253,0.24665003,0.826804695,0.599780335,1.150613759,0.40571958,DB0047210061428_,0.902093047,-0.190186773,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,fluoxetine,DB00472
,78175,DB00654,10061428,58,3758,37,2561,0.833388216,1.06826541,0.692940875,1.665273225,0.913437828,DB0065410061428_,0.090539965,0.06603622,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,latanoprost,DB00654
,78176,DB00843,10061428,40,2154,59,2114,0.053222245,0.665441747,0.431881185,1.01601003,0.13107343,DB0084310061428_,2.031997576,-0.407304178,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,donepezil,DB00843
,78184,DB00697,10028411,97,5999,13,1793,0.004089634,2.229831983,1.240980032,4.348704618,0.017391367,DB0069710028411_,4.051781346,0.801926239,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tizanidine,DB00697
,78186,DB00374,10037324,114,17602,26,5698,0.114592446,1.419313837,0.919473056,2.267418678,0.233014538,DB0037410037324_,1.45665443,0.350173542,NA,10037324,Pulmonary arterial pressure increased,10022891,Investigations,Inv,treprostinil,DB00374
,78188,DB06403,10037324,62,21409,11,6650,0.097308373,1.75066129,0.913315593,3.689371353,0.206820618,DB0640310037324_,1.575903441,0.559993597,NA,10037324,Pulmonary arterial pressure increased,10022891,Investigations,Inv,ambrisentan,DB06403
,78190,DB00559,10015090,110,9549,50,3256,0.100278362,0.750169716,0.530958499,1.07271444,0.211220189,DB0055910015090_,1.554854138,-0.28745581,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,78191,DB09140,10015090,131,3610,46,1752,0.072306735,1.382027812,0.975502066,1.988217457,0.165296794,DB0914010015090_,1.80001267,0.32355185,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,78197,DB01268,10028334,48,2095,57,3073,0.315684075,1.235161205,0.819966813,1.853859513,0.483326882,DB0126810028334_,0.72706208,0.211201492,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,sunitinib,DB01268
,78199,DB00635,10037032,34,33019,46,23748,0.006141369,0.531616955,0.330798878,0.846667082,0.02410601,DB0063510037032_,3.725294085,-0.631832058,NA,10037032,Proteinuria,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,78200,DB00722,10037032,18,25385,39,25993,0.007726904,0.472601612,0.254400807,0.846302449,0.028981404,DB0072210037032_,3.541100905,-0.749502504,NA,10037032,Proteinuria,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,78205,DB00399,10028372,68,6924,37,4961,0.19662081,1.316768288,0.868186631,2.025313186,0.344890089,DB0039910028372_,1.064529495,0.275180468,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,78208,DB01109,10007559,29,4383,33,4237,0.527375615,0.849532011,0.496654385,1.445912414,0.68496939,DB0110910007559_,0.378381127,-0.163069656,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,heparin,DB01109
,78214,DB00620,10037660,107,4721,71,3061,0.877006549,0.977128035,0.714518061,1.34307542,0.947535488,DB0062010037660_,0.053890888,-0.023137587,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,78216,DB01164,10065154,29,6495,30,7906,0.600483399,1.176653164,0.680684729,2.031248168,0.744865792,DB0116410065154_,0.294551221,0.162674107,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,calcium chloride,DB01164
,78219,DB00497,10015150,111,19156,58,16317,0.002473214,1.630134523,1.17535057,2.281511338,0.011568365,DB0049710015150_,4.45948109,0.488662541,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,78220,DB00497,10022061,48,19219,17,16358,0.001628934,2.403080194,1.356695201,4.459221873,0.008216565,DB0049710022061_,4.801603084,0.876751329,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,78223,DB00497,10039073,74,19193,29,16346,0.000319028,2.17311451,1.396281435,3.46550281,0.002121605,DB0049710039073_,6.155582261,0.776161396,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,78231,DB01050,10010071,90,18018,23,9348,0.001909002,2.030096874,1.27170848,3.36610019,0.009367707,DB0105010010071_,4.670486933,0.708083513,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,78239,DB00874,10047700,104,3231,52,1924,0.355089452,1.190882799,0.841352845,1.70335998,0.524891985,DB0087410047700_,0.644562781,0.17469488,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,guaifenesin,DB00874
,78240,DB00404,10012218,62,19830,75,9787,2.22243550850028e-07,0.408007916,0.28639883,0.579466633,3.72674432797001e-06,DB0040410012218_,12.49997554,-0.896468702,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,78241,DB01104,10012218,61,15402,41,7245,0.088312715,0.699850417,0.462986963,1.067613205,0.192439354,DB0110410012218_,1.647974219,-0.356888657,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,78244,DB00635,10026749,35,33018,21,23773,0.588392289,1.199986755,0.679160184,2.17008354,0.735348779,DB0063510026749_,0.307410363,0.18231052,NA,10026749,Mania,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,78245,DB01104,10026749,34,15429,24,7262,0.157805733,0.6667882,0.383635259,1.17620466,0.294544555,DB0110410026749_,1.222324997,-0.405282825,NA,10026749,Mania,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,78268,DB00472,10043607,38,10721,17,4295,0.765037526,0.895507571,0.492725495,1.693980291,0.870359749,DB0047210043607_,0.138848648,-0.110364603,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,fluoxetine,DB00472
,78272,DB00813,10043607,65,10507,43,10125,0.06626208,1.456637922,0.97485203,2.196066012,0.154645839,DB0081310043607_,1.866617683,0.376130987,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,fentanyl,DB00813
,78279,DB00355,10025482,43,1750,33,1230,0.724465122,0.91587149,0.564779034,1.497274742,0.838251783,DB0035510025482_,0.176436767,-0.087879219,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,aztreonam,DB00355
,78288,DB00601,10023676,59,846,43,868,0.103325319,1.407502205,0.922691776,2.161885296,0.216028159,DB0060110023676_,1.532346515,0.341816647,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,linezolid,DB00601
,78307,DB00316,10028035,69,65405,44,36909,0.556779578,0.884952719,0.597543698,1.322901982,0.710089821,DB0031610028035_,0.342363808,-0.12222106,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,78315,DB01076,10028035,41,25706,33,25550,0.415824729,1.234877127,0.761526141,2.016446082,0.585033844,DB0107610028035_,0.53608558,0.210971473,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,78320,DB01373,10006093,49,22671,18,7363,0.66999989,0.884101315,0.505559973,1.613569764,0.799758272,DB0137310006093_,0.223445757,-0.123183613,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,calcium,DB01373
,78321,DB00472,10007515,154,10605,61,4251,1,1.011981289,0.745935879,1.387703962,1,DB0047210007515_,0,0.011910081,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,fluoxetine,DB00472
,78326,DB00472,10062355,58,10701,22,4290,0.901623285,1.056906414,0.636079706,1.815858566,0.95705878,DB0047210062355_,0.043890468,0.055346163,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,78327,DB01373,10062355,145,22575,65,7316,0.035990594,0.722945841,0.535308617,0.985421093,0.097501959,DB0137310062355_,2.327882806,-0.324420968,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,78331,DB01373,10065154,117,22603,13,7368,3.63491856725489e-05,2.93381019,1.649227825,5.677159616,0.000335996,DB0137310065154_,7.998412023,1.076301984,female,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,calcium,DB01373
,78335,DB00904,10018100,54,23015,18,14438,0.020689491,1.881957397,1.086039952,3.411403855,0.063475141,DB0090410018100_,2.757106938,0.632312404,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,78339,DB00193,10045555,79,19241,28,8674,0.296570867,1.27188034,0.81642019,2.035112454,0.462413408,DB0019310045555_,0.771295965,0.240496388,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,78340,DB06228,10045555,21,15891,33,16043,0.133622097,0.642462803,0.353075922,1.14458342,0.260804694,DB0622810045555_,1.343983453,-0.442446358,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,78341,DB01013,10013709,87,930,50,557,0.854027822,1.042106872,0.715345324,1.53138837,0.928913404,DB0101310013709_,0.073739759,0.041244503,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,clobetasol propionate,DB01013
,78349,DB11750,10033371,81,2419,33,1480,0.050456205,1.501602932,0.984587224,2.336839893,0.125847261,DB1175010033371_,2.072686322,0.406533159,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,clobetasol,DB11750
,78353,DB11750,10037087,83,2417,38,1475,0.154067356,1.332842202,0.892153221,2.022997502,0.289623489,DB1175010037087_,1.239173512,0.287313656,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,clobetasol,DB11750
,78372,DB00331,10040752,28,24918,61,20691,1.46566232676917e-05,0.381157203,0.234463774,0.60574772,0.000151972,DB0033110040752_,8.791813427,-0.964543382,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,metformin,DB00331
,78381,DB01118,10022437,35,3028,45,4664,0.423366368,1.197967292,0.745681945,1.910456006,0.59219248,DB0111810022437_,0.523923561,0.180626197,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,amiodarone,DB01118
,78386,DB01109,10008111,53,4359,42,4228,0.353975992,1.223950767,0.799116952,1.885159827,0.523844211,DB0110910008111_,0.646560946,0.20208396,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,heparin,DB01109
,78390,DB01109,10018985,43,4369,68,4202,0.012660504,0.608220877,0.40419586,0.90644706,0.042964134,DB0110910018985_,3.147389601,-0.497217178,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,heparin,DB01109
,78398,DB01109,10061818,66,4346,31,4239,0.000685875,2.07643734,1.332611509,3.29948781,0.004024414,DB0110910061818_,5.515375932,0.730653608,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,78400,DB00193,10005425,40,19280,14,8688,0.464488847,1.287445201,0.685313634,2.563500899,0.631531842,DB0019310005425_,0.459606915,0.252659791,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,tramadol,DB00193
,78401,DB00476,10005425,44,17213,12,6165,0.451085063,1.313218662,0.681247155,2.733359054,0.618748643,DB0047610005425_,0.480056158,0.272481117,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,duloxetine,DB00476
,78402,DB01076,10005425,96,25651,78,25505,0.196976735,1.223757099,0.89774446,1.672555326,0.345364605,DB0107610005425_,1.063154595,0.201925716,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,atorvastatin,DB01076
,78407,DB00051,10005557,73,25658,39,11381,0.356667454,0.830286398,0.555016757,1.258966203,0.526345565,DB0005110005557_,0.641797314,-0.18598458,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,adalimumab,DB00051
,78408,DB00996,10005557,194,38759,137,22288,0.067226091,0.814304839,0.650534746,1.021599418,0.15640271,DB0099610005557_,1.855321126,-0.205420488,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,gabapentin,DB00996
,78413,DB13961,10005557,60,9397,78,6336,0.000159174,0.518671507,0.363562635,0.736825355,0.001187085,DB1396110005557_,6.736254791,-0.65648453,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,fish oil,DB13961
,78428,DB00158,10008629,31,16784,21,8083,0.237136744,0.710908565,0.395352321,1.302635107,0.394477521,DB0015810008629_,0.930193122,-0.341211458,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,folic acid,DB00158
,78429,DB01076,10008629,42,25705,47,25536,0.597087168,0.887744369,0.571083608,1.37596088,0.742395301,DB0107610008629_,0.297873427,-0.11907145,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,atorvastatin,DB01076
,78436,DB01593,10013709,53,1080,20,678,0.06451685,1.663177334,0.96770155,2.964597491,0.151602485,DB0159310013709_,1.886493417,0.508729829,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,zinc,DB01593
,78438,DB10708,10013709,44,976,8,447,0.013850943,2.517661638,1.159809548,6.244137196,0.046161028,DB1070810013709_,3.075619386,0.923330549,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,flax seed,DB10708
,78451,DB00193,10037153,185,19135,61,8641,0.037609166,1.369579119,1.018993238,1.862676974,0.100806296,DB0019310037153_,2.294554469,0.31450348,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,78452,DB00996,10037153,315,38638,106,22319,7.46344028492486e-07,1.716567677,1.372360821,2.161304955,1.10521987543239e-05,DB0099610037153_,11.41288117,0.54032676,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,78453,DB05679,10037153,434,6497,324,4585,0.46916642,0.94532227,0.812577425,1.100551807,0.635491966,DB0567910037153_,0.45335583,-0.056229383,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,ustekinumab,DB05679
,78456,DB13961,10037153,163,9294,76,6338,0.006386345,1.46255849,1.10510973,1.950245977,0.024887336,DB1396110037153_,3.693396209,0.380187293,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,fish oil,DB13961
,78457,DB01156,10060795,42,13580,15,6313,0.476129052,1.301587109,0.706551278,2.529034933,0.641567239,DB0115610060795_,0.443841284,0.263584373,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,bupropion,DB01156
,78458,DB01373,10060795,97,22623,15,7366,0.005606438,2.105361818,1.214659737,3.908347247,0.022423484,DB0137310060795_,3.797646455,0.744487337,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,calcium,DB01373
,78460,DB05679,10060795,25,6906,30,4879,0.054712139,0.588780826,0.331554025,1.037080675,0.133852251,DB0567910060795_,2.011018691,-0.529701276,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,ustekinumab,DB05679
,78479,DB00169,10067585,51,38640,23,18152,1,1.041656483,0.62491879,1.786568349,1,DB0016910067585_,0,0.040812218,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,78482,DB00996,10067585,42,38911,20,22405,0.51273717,1.209139984,0.694068788,2.174668732,0.672889136,DB0099610067585_,0.396174694,0.18990935,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,78495,DB00864,10013950,34,6835,45,8347,0.73557168,0.922677596,0.572467428,1.474792299,0.847238699,DB0086410013950_,0.165772807,-0.080475405,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,78514,DB00222,10010305,29,3177,40,3088,0.182659369,0.704732283,0.420209446,1.168805671,0.327267997,DB0022210010305_,1.116975883,-0.349937288,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,glimepiride,DB00222
,78516,DB00490,10010305,63,4007,39,1537,0.025273367,0.61968475,0.407261962,0.953296368,0.074104573,DB0049010010305_,2.602278032,-0.478544398,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,buspirone,DB00490
,78519,DB00410,10016173,76,1529,31,978,0.042175603,1.567877885,1.011206175,2.483634736,0.110027863,DB0041010016173_,2.207021645,0.449723039,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,mupirocin,DB00410
,78520,DB00490,10016173,153,3917,39,1537,0.017388966,1.539306138,1.070902556,2.259139932,0.055378806,DB0049010016173_,2.893558314,0.431331755,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,buspirone,DB00490
,78521,DB00544,10016173,33,2402,40,2613,0.723655587,0.897499661,0.546475086,1.464864279,0.837567909,DB0054410016173_,0.177252933,-0.108142536,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,fluorouracil,DB00544
,78522,DB00650,10016173,39,2092,32,1982,0.632229572,1.154625886,0.701778075,1.912211813,0.770929408,DB0065010016173_,0.260158469,0.143776384,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,leucovorin,DB00650
,78524,DB01238,10016173,125,5125,60,3442,0.033792361,1.39913432,1.017126129,1.94276081,0.092955074,DB0123810016173_,2.375638973,0.335853702,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole,DB01238
,78525,DB00193,10028372,171,19149,73,8629,0.728725271,1.055568935,0.797016032,1.409836328,0.841846954,DB0019310028372_,0.172157046,0.054079896,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,78529,DB00193,10029354,105,19215,59,8643,0.176138541,0.800532515,0.57585363,1.12188138,0.318878817,DB0019310029354_,1.142944132,-0.222478128,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,tramadol,DB00193
,78532,DB00526,10029354,44,1554,74,1820,0.06080463,0.69644448,0.465315001,1.031830294,0.144906814,DB0052610029354_,1.931664404,-0.361767202,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,oxaliplatin,DB00526
,78533,DB00544,10029354,58,2377,99,2554,0.005708375,0.629542751,0.444972805,0.883815336,0.022749547,DB0054410029354_,3.783210039,-0.462761516,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,fluorouracil,DB00544
,78534,DB00656,10029354,42,11971,43,6576,0.004410793,0.536552222,0.341854658,0.841661197,0.018482017,DB0065610029354_,3.990957079,-0.622591384,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,trazodone,DB00656
,78535,DB00762,10029354,30,1133,51,1318,0.112973238,0.684386421,0.417769535,1.103705266,0.230533464,DB0076210029354_,1.467359247,-0.379232578,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,irinotecan,DB00762
,78542,DB00706,10035528,11,1064,232,15693,0.288572935,0.699303325,0.343195564,1.280104718,0.45361598,DB0070610035528_,0.790504298,-0.357670689,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,tamsulosin,DB00706
,78550,DB00656,10046543,52,11961,16,6603,0.041882749,1.794091531,1.007345942,3.369502992,0.109486629,DB0065610046543_,2.211952842,0.584498783,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,trazodone,DB00656
,78556,DB08908,10057362,86,10587,30,3249,0.582272968,0.879730423,0.573312487,1.383972405,0.730429044,DB0890810057362_,0.314123187,-0.128139756,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,dimethyl fumarate,DB08908
,78557,DB00476,10048439,173,17084,20,6157,4.15378696988898e-08,3.117499859,1.95498887,5.235695368,8.16316190680612e-07,DB0047610048439_,14.01846407,1.137031353,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,78558,DB01281,10011224,152,8780,15,1783,0.004720661,2.057700177,1.20523276,3.776930643,0.019531336,DB0128110011224_,3.935735114,0.72158894,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,abatacept,DB01281
,78560,DB06403,10038435,151,21320,58,6603,0.165439836,0.806314755,0.59113495,1.112642988,0.304714882,DB0640310038435_,1.188378753,-0.215281098,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,ambrisentan,DB06403
,78561,DB06403,10062237,55,21416,16,6645,0.889648528,1.066577533,0.601823319,1.995599817,0.954173684,DB0640310062237_,0.046909566,0.064454954,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,ambrisentan,DB06403
,78572,DB01101,10012735,947,6642,462,3446,0.321850172,1.063469891,0.943246897,1.200124176,0.490156078,DB0110110012735_,0.713031411,0.061537044,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,78574,DB00697,10019063,61,6035,31,1775,0.017101384,0.578793904,0.368432597,0.925947866,0.054641692,DB0069710019063_,2.906958101,-0.546808817,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,tizanidine,DB00697
,78576,DB00682,10003246,92,19367,36,16328,5.50923993311808e-05,2.154454139,1.449913798,3.263800764,0.000479822,DB0068210003246_,7.642094721,0.767537392,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,78579,DB00682,10061394,55,19404,18,16346,0.000238932,2.57386472,1.487697742,4.659166802,0.001671633,DB0068210061394_,6.393954232,0.945408552,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,78586,DB00704,10024855,23,4333,40,5154,0.16328494,0.683976817,0.390249929,1.172524233,0.301792683,DB0070410024855_,1.198014978,-0.379831255,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,naltrexone,DB00704
,78594,DB00316,10008612,39,65435,24,36929,0.793210336,0.917089889,0.537740569,1.594484196,0.887894288,DB0031610008612_,0.118902588,-0.086549787,NA,10008612,Cholecystitis,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,78604,DB00316,10025102,49,65425,26,36927,0.90435925,1.063714025,0.648177024,1.783469923,0.957497529,DB0031610025102_,0.043432138,0.061766581,NA,10025102,Lung infiltration,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,78616,DB00005,10067585,47,128035,34,42385,0.000731046,0.457611309,0.288121269,0.733813068,0.004242116,DB0000510067585_,5.462693075,-0.781735124,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,etanercept,DB00005
,78619,DB00316,10016326,119,65355,42,36911,0.008411969,1.600193975,1.116654681,2.333032103,0.031004502,DB0031610016326_,3.473622851,0.470124856,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,78621,DB00480,10067621,63,67365,62,67600,0.928917292,1.019676518,0.706477566,1.47219003,0.970529892,DB0048010067621_,0.029913076,0.019485438,NA,10067621,Oral disorder,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,78623,DB01238,10034010,22,5228,36,3466,0.000711874,0.405188024,0.226656994,0.709060864,0.004149456,DB0123810034010_,5.48477792,-0.903404064,NA,10034010,Parkinsonism,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,78625,DB00065,10020141,27,9437,35,4922,0.000410661,0.402374351,0.233941082,0.6850896,0.002619639,DB0006510020141_,5.944718682,-0.910372402,NA,10020141,Histoplasmosis,10021881,Infections and infestations,Infec,infliximab,DB00065
,78629,DB00230,10003983,112,19562,42,8609,0.42984963,1.173551731,0.81553297,1.717149877,0.598331746,DB0023010003983_,0.513609919,0.160034818,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,78634,DB00181,10006451,84,9772,23,5848,0.000585339,2.185523289,1.36262333,3.637842283,0.003522758,DB0018110006451_,5.648510942,0.781855291,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,baclofen,DB00181
,78635,DB00230,10006451,209,19465,44,8607,1.93366836706268e-06,2.100299789,1.509636883,2.980286633,2.57088887345688e-05,DB0023010006451_,10.56867376,0.742080091,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,pregabalin,DB00230
,78646,DB00230,10045555,41,19633,31,8620,0.028532714,0.580700101,0.355118068,0.958407978,0.081462269,DB0023010045555_,2.507615319,-0.543520832,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,78647,DB00230,10048334,120,19554,37,8614,0.067583003,1.428747631,0.979979341,2.127251726,0.157010716,DB0023010048334_,1.851441218,0.356798278,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,78654,DB00193,10015090,101,19219,49,8653,0.659093213,0.928032722,0.652782762,1.334846417,0.791749239,DB0019310015090_,0.233510554,-0.074688286,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,78657,DB00863,10015090,74,10599,34,5806,0.420900168,1.192203883,0.78310341,1.848436595,0.589904339,DB0086310015090_,0.527794893,0.175803597,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,78659,DB00169,10018276,42,38649,12,18163,0.144641986,1.644802954,0.849895265,3.432900674,0.276512936,DB0016910018276_,1.285497676,0.497620592,NA,10018276,Gingival bleeding,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,78694,DB06700,10020642,52,2173,16,602,0.765789686,0.900387294,0.501712569,1.702264545,0.870904571,DB0670010020642_,0.138222871,-0.104930282,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,desvenlafaxine,DB06700
,78696,DB06643,10013786,178,52243,16,7499,0.081267262,1.596879093,0.955864216,2.856262448,0.180523429,DB0664310013786_,1.711894708,0.468051158,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,78698,DB06643,10040844,113,52308,19,7496,0.510117667,0.852297781,0.520958915,1.468841073,0.670606515,DB0664310040844_,0.399572729,-0.159819305,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,78703,DB00722,10004146,31,25372,37,25995,0.546398083,0.858413888,0.514834564,1.42244495,0.701067734,DB0072210004146_,0.355150772,-0.152668909,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lisinopril,DB00722
,78705,DB01076,10004146,23,25724,39,25544,0.042236836,0.585626663,0.333791593,1.005582896,0.110171205,DB0107610004146_,2.205719717,-0.535072786,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,atorvastatin,DB01076
,78715,DB00186,10019974,77,16824,33,9975,0.137831085,1.383424193,0.908214649,2.149575886,0.266683112,DB0018610019974_,1.321694172,0.324561725,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,lorazepam,DB00186
,78716,DB00281,10019974,60,11398,19,5652,0.093780457,1.565887868,0.920529647,2.781351815,0.201408306,DB0028110019974_,1.602421059,0.448452991,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,lidocaine,DB00281
,78717,DB00331,10019974,87,24859,56,20696,0.152528645,1.293394615,0.913491299,1.84425465,0.287512312,DB0033110019974_,1.246489594,0.257270247,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,metformin,DB00331
,78718,DB00736,10019974,57,10534,24,5529,0.412605571,1.246510198,0.760322551,2.102821791,0.582065607,DB0073610019974_,0.541172111,0.220347805,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,78719,DB00996,10019974,257,38696,121,22304,0.068597231,1.224273543,0.981885336,1.533361908,0.15877059,DB0099610019974_,1.840294946,0.202347642,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,gabapentin,DB00996
,78720,DB00999,10019974,110,21320,37,12202,0.004463548,1.701485313,1.161840539,2.542792509,0.018654663,DB0099910019974_,3.981659119,0.531501583,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,78721,DB01076,10019974,138,25609,80,25503,0.000102129,1.717831618,1.294213092,2.293125688,0.000812608,DB0107610019974_,7.115261462,0.541062808,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,78722,DB01136,10019974,34,9850,33,11082,0.624249741,1.159159588,0.696047184,1.932495666,0.764123429,DB0113610019974_,0.269025947,0.14769525,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,carvedilol,DB01136
,78746,DB00563,10022081,119,46527,25,15323,0.041986816,1.567581165,1.011553954,2.520175391,0.109681533,DB0056310022081_,2.210174262,0.449533772,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,78747,DB00563,10064355,107,46539,52,15296,0.026743996,0.676307878,0.480905115,0.961554485,0.077436211,DB0056310064355_,2.558300766,-0.391106865,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,78754,DB01592,10012174,88,6188,45,3022,0.78122359,0.955029212,0.657624253,1.403805865,0.880853726,DB0159210012174_,0.126863699,-0.046013351,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,iron,DB01592
,78755,DB00999,10047942,249,21181,115,12124,0.062393245,1.239399199,0.988535734,1.561536353,0.147928241,DB0099910047942_,1.911027978,0.214626745,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,78758,DB01592,10047942,97,6179,43,3024,0.65055173,1.103979169,0.761174826,1.624414724,0.785075072,DB0159210047942_,0.241975933,0.098921079,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,iron,DB01592
,78770,DB00958,10021036,83,4511,24,2561,0.00308582,1.963209963,1.23013931,3.242807452,0.01384261,DB0095810021036_,4.280003778,0.67458087,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,carboplatin,DB00958
,78771,DB01229,10021036,98,5643,28,2681,0.016190258,1.662766014,1.079860167,2.636005931,0.052312345,DB0122910021036_,2.950522897,0.508482489,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,paclitaxel,DB01229
,78779,DB01109,10016256,241,4171,114,4156,3.6687425455932e-11,2.106245781,1.671397825,2.667089897,1.28662972396154e-09,DB0110910016256_,20.47123965,0.744907112,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,78780,DB09140,10019211,556,3185,137,1661,2.82580330532911e-15,2.116215744,1.735127907,2.594510157,1.79411207441004e-13,DB0914010019211_,29.34909598,0.749629467,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,oxygen,DB09140
,78782,DB00046,10037423,35,5424,21,4671,0.226468313,1.435234225,0.8112336,2.598628325,0.381474549,DB0004610037423_,0.963711144,0.361328059,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin lispro,DB00046
,78786,DB00695,10061105,47,28002,49,20479,0.09749319,0.701506288,0.459790532,1.06920205,0.207104579,DB0069510061105_,1.574531402,-0.354525416,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,furosemide,DB00695
,78793,DB00512,10038540,96,4641,135,4963,0.045511075,0.760472016,0.577357395,0.998542057,0.116537614,DB0051210038540_,2.149541192,-0.273815965,NA,10038540,Renal tubular necrosis,10038359,Renal and urinary disorders,Renal,vancomycin,DB00512
,78796,DB00016,10047899,38,2724,13,2277,0.004371585,2.442941342,1.269234677,5.010739882,0.018348442,DB0001610047899_,3.998210594,0.893202781,NA,10047899,Weight increased,10022891,Investigations,Inv,erythropoietin,DB00016
,78797,DB00231,10000059,36,3260,19,2120,0.491444532,1.232093456,0.686141835,2.280441408,0.654570398,DB0023110000059_,0.42377614,0.208714719,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,temazepam,DB00231
,78799,DB00316,10001480,97,65377,79,36874,0.018179398,0.692562467,0.509103623,0.944484108,0.057312801,DB0031610001480_,2.859231282,-0.36735684,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,78801,DB00437,10001480,19,6902,37,11509,0.678808455,0.856260045,0.464750956,1.529032602,0.80556595,DB0043710001480_,0.216210205,-0.155181158,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,78803,DB00451,10001480,112,47159,56,15363,0.011688907,0.651545775,0.468376814,0.915277915,0.040317947,DB0045110001480_,3.210958578,-0.428407624,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,78805,DB08877,10003549,104,3185,121,3108,0.198120877,0.838748825,0.63598727,1.104618016,0.346792345,DB0887710003549_,1.059029108,-0.175843991,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,78806,DB00370,10013709,242,4299,155,3508,0.022717567,1.273980038,1.031725877,1.576784119,0.068235773,DB0037010013709_,2.684786317,0.242145889,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,78807,DB08877,10021097,25,3264,30,3199,0.49963308,0.816765026,0.459513029,1.44023105,0.661372159,DB0887710021097_,0.413438574,-0.202403831,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ruxolitinib,DB08877
,78823,DB00451,10041660,34,47237,22,15397,0.018553579,0.503726416,0.28611662,0.904379193,0.058234022,DB0045110041660_,2.843285531,-0.685721983,NA,10041660,Splenomegaly,10005329,Blood and lymphatic system disorders,Blood,levothyroxine,DB00451
,78826,DB00437,10047943,40,6881,71,11475,0.844166357,0.939510317,0.62044084,1.405138824,0.921217807,DB0043710047943_,0.082058781,-0.062396479,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,allopurinol,DB00437
,78831,DB09401,10013968,54,706,40,720,0.165955526,1.37647528,0.88501674,2.15607382,0.305370574,DB0940110013968_,1.186229243,0.319526087,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,isosorbide,DB09401
,78832,DB00343,10000081,129,8607,44,5051,0.001480287,1.72046789,1.210839963,2.48550128,0.007607653,DB0034310000081_,4.878600556,0.542596283,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,78835,DB00678,10000087,218,15381,103,10621,0.001629786,1.461482803,1.149340624,1.868473966,0.008219286,DB0067810000087_,4.80127189,0.379451539,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,78836,DB06589,10000087,42,1988,54,2599,1,1.016823562,0.659833285,1.557692352,1,DB0658910000087_,0,0.016683613,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,pazopanib,DB06589
,78837,DB00627,10012735,75,1254,97,1502,0.636831431,0.926107682,0.66932987,1.277440896,0.774260004,DB0062710012735_,0.255847539,-0.076764764,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,niacin,DB00627
,78838,DB00343,10013911,30,8706,30,5065,0.043374438,0.581834323,0.338409999,1.000215851,0.112411826,DB0034310013911_,2.185586134,-0.54156954,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,78840,DB06589,10013911,33,1997,64,2589,0.062948268,0.668535893,0.423611129,1.037613072,0.148848077,DB0658910013911_,1.904829114,-0.402665192,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,pazopanib,DB06589
,78842,DB00627,10016256,81,1248,79,1520,0.191286667,1.248681122,0.895933688,1.740981492,0.338191857,DB0062710016256_,1.08414192,0.222087892,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,niacin,DB00627
,78843,DB00627,10019211,60,1269,38,1561,0.001824829,1.941798222,1.262902077,3.018392157,0.009025428,DB0062710019211_,4.70770939,0.663614463,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,niacin,DB00627
,78844,DB06589,10019211,75,1955,70,2583,0.041130135,1.415474377,1.002590247,2.000493979,0.107948636,DB0658910019211_,2.226099756,0.347464724,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pazopanib,DB06589
,78845,DB00627,10028813,75,1254,69,1530,0.103286589,1.326051566,0.934927868,1.883139502,0.215964362,DB0062710028813_,1.532641877,0.28220578,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,niacin,DB00627
,78846,DB06589,10028813,231,1799,257,2396,0.066596443,1.197059289,0.987266028,1.450904937,0.155218769,DB0658910028813_,1.862919747,0.179867956,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pazopanib,DB06589
,78847,DB00627,10047700,42,1287,38,1561,0.211179154,1.340425888,0.837894652,2.150457356,0.362729142,DB0062710047700_,1.014098888,0.29298739,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,niacin,DB00627
,78848,DB06589,10047700,99,1931,115,2538,0.397120388,1.131447572,0.850190367,1.50352535,0.566753679,DB0658910047700_,0.567830498,0.12349785,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pazopanib,DB06589
,78850,DB06626,10061428,42,646,68,1384,0.1734602,1.323125263,0.86817896,1.996650637,0.315485114,DB0662610061428_,1.15364378,0.279996562,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,axitinib,DB06626
,78852,DB05259,10012735,133,11137,32,2696,1,1.006128083,0.677962744,1.533669313,1,DB0525910012735_,0,0.006109383,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,glatiramer,DB05259
,78853,DB05259,10016334,85,11185,24,2704,0.468948243,0.856186541,0.537701984,1.411744503,0.635342473,DB0525910016334_,0.453591098,-0.155267005,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,78867,DB00678,10008479,221,15378,137,10587,0.357402444,1.110589498,0.89200038,1.386679327,0.52711902,DB0067810008479_,0.640328912,0.104890954,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,78868,DB01109,10008479,105,4307,115,4155,0.374801924,0.88083443,0.667156457,1.161939276,0.544637122,DB0110910008479_,0.607635538,-0.126885605,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,78872,DB00193,10014020,47,19273,10,8692,0.030676378,2.119621561,1.056398262,4.707224934,0.086206083,DB0019310014020_,2.451014537,0.751237564,NA,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,tramadol,DB00193
,78873,DB00051,10015958,39,25692,18,11402,0.886336293,0.961556997,0.536839814,1.786550292,0.952748725,DB0005110015958_,0.048404077,-0.039201436,NA,10015958,Eye pain,10015919,Eye disorders,Eye,adalimumab,DB00051
,78874,DB00193,10015958,52,19268,8,8694,0.001976825,2.932755396,1.382748028,7.152484153,0.009634867,DB0019310015958_,4.642366772,1.075942389,female,10015958,Eye pain,10015919,Eye disorders,Eye,tramadol,DB00193
,78875,DB00193,10028836,133,19187,32,8670,0.000942764,1.878041109,1.267555553,2.858522338,0.005246225,DB0019310028836_,5.25024656,0.63022927,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,78876,DB00193,10033433,79,19241,21,8681,0.030156941,1.697237224,1.037443282,2.894150841,0.085043548,DB0019310033433_,2.464591824,0.529001766,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,78877,DB00051,10036790,31,25700,21,11399,0.134600115,0.654758874,0.3642138,1.199437031,0.262090823,DB0005110036790_,1.339064184,-0.423488243,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,78878,DB00193,10036790,73,19247,22,8680,0.11925218,1.496423077,0.917562012,2.533990088,0.240204112,DB0019310036790_,1.426266251,0.403077645,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,78883,DB00207,10008469,81,8999,38,5417,0.217644311,1.283094914,0.861100926,1.942377412,0.370727948,DB0020710008469_,0.99228678,0.249275061,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,78884,DB00668,10008469,121,9970,29,4274,0.003992983,1.788592065,1.182495313,2.787588674,0.017059012,DB0066810008469_,4.07107667,0.581428755,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,78885,DB00999,10008469,148,21282,50,12189,0.001062393,1.695277539,1.221550133,2.387183682,0.005789964,DB0099910008469_,5.151629232,0.527846467,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,78886,DB01109,10008469,40,4372,32,4238,0.477979923,1.211659659,0.740609459,1.99673944,0.643286259,DB0110910008469_,0.441165461,0.191991039,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,78888,DB00165,10037660,73,2072,57,1309,0.271239953,0.809150436,0.560212339,1.173516212,0.434027292,DB0016510037660_,0.834647863,-0.211770426,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,pyridoxine,DB00165
,78889,DB14513,10037660,167,7010,68,3496,0.183093357,1.22473313,0.915639561,1.653562587,0.32775625,DB1451310037660_,1.115485086,0.202722967,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,78890,DB00115,10046306,162,18263,52,10420,0.000196456,1.777456764,1.291850407,2.480905875,0.00141981,DB0011510046306_,6.55723203,0.575183558,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,78893,DB00213,10046306,130,18765,56,13365,0.001651878,1.653363153,1.198775744,2.305883384,0.008312361,DB0021310046306_,4.790011629,0.502811488,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,78894,DB00281,10046306,186,11272,65,5606,0.014868014,1.423125769,1.065430405,1.921442059,0.048963948,DB0028110046306_,3.016671006,0.352855698,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,lidocaine,DB00281
,78895,DB00678,10046306,111,15488,53,10671,0.031091578,1.442948148,1.030141235,2.043392057,0.087107454,DB0067810046306_,2.44061282,0.366688346,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,losartan,DB00678
,78896,DB01222,10046306,127,9147,61,5344,0.223862824,1.216299788,0.887681603,1.682218847,0.378346525,DB0122210046306_,0.971944772,0.195813289,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,budesonide,DB01222
,78897,DB01409,10046306,97,5934,32,3934,0.000392196,2.009459905,1.332104943,3.104316496,0.002522051,DB0140910046306_,5.982682687,0.697865982,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,tiotropium,DB01409
,78898,DB14513,10046306,55,7122,20,3544,0.26834637,1.3684155,0.805672761,2.414429765,0.430839223,DB1451310046306_,0.842020291,0.313653501,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,magnesium,DB14513
,78899,DB00612,10016256,62,1078,42,598,0.344221258,0.818993955,0.537265073,1.258737971,0.513542911,DB0061210016256_,0.666421688,-0.199678576,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,bisoprolol,DB00612
,78901,DB00165,10019211,83,2062,30,1336,0.005924531,1.792283946,1.160198612,2.836081002,0.023436871,DB0016510019211_,3.753444793,0.583490754,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pyridoxine,DB00165
,78904,DB00215,10027599,78,11025,10,5266,9.19199306156367e-06,3.725098474,1.919596802,8.079352326,0.000100861,DB0021510027599_,9.201771315,1.315093288,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,78905,DB00281,10027599,120,11338,14,5657,1.49164563083695e-09,4.275895123,2.449004376,8.065903207,3.99469234911352e-08,DB0028110027599_,17.03571418,1.452993466,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,78906,DB00343,10027599,44,8692,8,5087,0.000835453,3.218652124,1.497237928,7.923108233,0.004746029,DB0034310027599_,5.350447064,1.168962677,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,78908,DB00668,10027599,135,9956,19,4284,3.17995912555516e-07,3.057018209,1.880613138,5.24266832,5.14845861504264e-06,DB0066810027599_,12.17681319,1.117439999,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,epinephrine,DB00668
,78909,DB00669,10027599,324,6053,38,1059,0.022065084,1.491641379,1.056097489,2.160172713,0.066783741,DB0066910027599_,2.706295623,0.39987711,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,sumatriptan,DB00669
,78916,DB00316,10019909,72,65402,55,36898,0.096148077,0.738577472,0.512585191,1.069261861,0.204972141,DB0031610019909_,1.584881205,-0.303029278,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,78917,DB00331,10019909,32,24914,30,20722,0.702245624,0.887193875,0.521905967,1.511923658,0.821369191,DB0033110019909_,0.196782586,-0.119691747,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,78921,DB01234,10019909,18,31607,56,32832,1.95765877945501e-05,0.333863256,0.184681571,0.576688523,0.00019599,DB0123410019909_,8.537449126,-1.097023783,male,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,78924,DB08877,10012735,157,3132,139,3090,0.372659611,1.114330926,0.876273515,1.418243991,0.542394619,DB0887710012735_,0.611761463,0.108254158,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ruxolitinib,DB08877
,78926,DB00046,10049803,35,5424,16,4676,0.03488127,1.885713935,1.015038615,3.653764377,0.095193575,DB0004610049803_,2.351842829,0.634306494,NA,10049803,Blood glucose fluctuation,10022891,Investigations,Inv,insulin lispro,DB00046
,78938,DB00030,10064355,71,2135,79,1742,0.065980466,0.733363476,0.521201004,1.030312424,0.154121437,DB0003010064355_,1.870014436,-0.310113826,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin human,DB00030
,78939,DB00046,10064355,180,5279,161,4531,0.740353937,0.959583961,0.768525323,1.19901363,0.850840538,DB0004610064355_,0.16153055,-0.041255462,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin lispro,DB00046
,78940,DB00335,10064355,31,8435,26,5439,0.342761508,0.768842406,0.441232766,1.349761188,0.512077198,DB0033510064355_,0.669279888,-0.262869264,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,atenolol,DB00335
,78941,DB00343,10064355,32,8704,18,5077,1,1.036968366,0.56411748,1.964248446,1,DB0034310064355_,0,0.036301424,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,78942,DB00722,10064355,125,25278,110,25922,0.266293142,1.165309759,0.894098553,1.520544148,0.42845868,DB0072210064355_,0.847560974,0.15298694,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,78943,DB00736,10064355,52,10539,30,5523,0.726784632,0.908367405,0.568047319,1.476667025,0.840177419,DB0073610064355_,0.174142197,-0.096106351,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,esomeprazole,DB00736
,78944,DB00996,10064355,121,38832,62,22363,0.489396262,1.123932177,0.820494097,1.55284383,0.65276739,DB0099610064355_,0.426534431,0.116833409,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,78950,DB00182,10064355,40,5154,19,2833,0.682748892,1.157163578,0.653291876,2.119746364,0.808180614,DB0018210064355_,0.212969713,0.145971819,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,amphetamine,DB00182
,78951,DB00331,10064355,152,24794,129,20623,0.904365185,0.980070392,0.769403836,1.250033379,0.957497529,DB0033110064355_,0.043432138,-0.020130882,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,78952,DB00338,10064355,153,33521,93,22179,0.557072677,1.088526656,0.835285334,1.424923448,0.710274081,DB0033810064355_,0.342104355,0.08482509,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,78953,DB00381,10064355,114,29246,94,22793,0.726374842,0.945199626,0.712579182,1.256235151,0.839835939,DB0038110064355_,0.174548717,-0.05635913,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,78954,DB00678,10064355,93,15506,61,10663,0.805518652,1.048417846,0.750247807,1.474278585,0.894755964,DB0067810064355_,0.111204263,0.047282214,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,78956,DB00904,10064355,64,23005,34,14422,0.468157911,1.180013262,0.766398544,1.846148144,0.634731042,DB0090410064355_,0.454553926,0.165525677,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,78958,DB00999,10064355,90,21340,56,12183,0.60611227,0.91752124,0.649558079,1.305776577,0.749143536,DB0099910064355_,0.288824677,-0.086079549,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,78960,DB01098,10064355,39,8110,31,7178,0.719303735,1.113460163,0.676228306,1.847919612,0.834262837,DB0109810064355_,0.181206774,0.10747243,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,rosuvastatin,DB01098
,78962,DB01234,10064355,34,31591,37,32851,0.905681317,0.95555801,0.58167417,1.565444148,0.957861963,DB0123410064355_,0.0430516,-0.045459806,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,78964,DB13961,10064355,56,9401,32,6382,0.513601586,1.187972323,0.755201031,1.897971061,0.673603158,DB1396110064355_,0.395114128,0.172247924,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,fish oil,DB13961
,78998,DB00316,10012601,175,65299,94,36859,0.750672926,1.050868647,0.812999232,1.365436019,0.859058816,DB0031610012601_,0.151917889,0.049617105,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,79000,DB00005,10061458,44,128038,9,42410,0.206332463,1.619287112,0.780123353,3.772820544,0.356864537,DB0000510061458_,1.030399018,0.481985998,NA,10061458,Feeling of body temperature change,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,79001,DB00678,10021143,71,15528,36,10688,0.140264155,1.357474299,0.896017609,2.089197182,0.270227091,DB0067810021143_,1.308492596,0.30562584,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,79002,DB00158,10022611,35,16780,18,8086,0.883417648,0.936998696,0.516114374,1.758468527,0.951268864,DB0015810022611_,0.04995854,-0.065073389,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,79003,DB00563,10022611,188,46458,53,15295,0.369375739,1.167800903,0.856338955,1.616509202,0.539031828,DB0056310022611_,0.61798066,0.15512241,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,79005,DB00207,10012735,416,8664,231,5224,0.339561977,1.08584784,0.918822754,1.285666759,0.508641491,DB0020710012735_,0.676011851,0.082361102,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,79006,DB00421,10005725,44,8859,33,5219,0.29010383,0.78551864,0.48819251,1.275125129,0.455303111,DB0042110005725_,0.786791904,-0.241411091,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,spironolactone,DB00421
,79008,DB00421,10005851,33,8870,25,5227,0.343584606,0.777891258,0.448133436,1.366142631,0.512893885,DB0042110005851_,0.667686306,-0.251168536,NA,10005851,Blood urea increased,10022891,Investigations,Inv,spironolactone,DB00421
,79010,DB01136,10005851,25,9859,33,11082,0.599321349,0.851559353,0.485104621,1.477464099,0.744003668,DB0113610005851_,0.295709315,-0.160686077,NA,10005851,Blood urea increased,10022891,Investigations,Inv,carvedilol,DB01136
,79012,DB00421,10006093,31,8872,52,5200,3.12589364138293e-06,0.349440475,0.216151724,0.556344913,3.92493481087049e-05,DB0042110006093_,10.14557572,-1.051422047,male,10006093,Bradycardia,10007541,Cardiac disorders,Card,spironolactone,DB00421
,79021,DB00421,10013710,50,8853,87,5165,3.58193782025779e-10,0.335324481,0.231520301,0.481092179,1.07662933796999e-08,DB0042110013710_,18.34684557,-1.092656616,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,79030,DB00203,10057925,51,13827,19,8919,0.048929036,1.731387925,1.003956692,3.107627813,0.122977597,DB0020310057925_,2.095753078,0.548923356,NA,10057925,Transplant evaluation,10022891,Investigations,Inv,sildenafil,DB00203
,79032,DB08877,10048959,61,3228,39,3190,0.034574401,1.545579606,1.014178712,2.380446418,0.094576764,DB0887710048959_,2.358343452,0.43539899,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,79038,DB01181,10061818,18,555,32,888,0.769326859,0.900044913,0.470826363,1.670978082,0.873663127,DB0118110061818_,0.135060416,-0.105310613,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,ifosfamide,DB01181
,79043,DB08907,10062237,25,4228,36,3874,0.094196042,0.636340769,0.365425128,1.092007321,0.202068307,DB0890710062237_,1.599149484,-0.452021059,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,canagliflozin,DB08907
,79044,DB00099,10003549,89,2296,62,1893,0.359876113,1.183477737,0.841014954,1.6741274,0.52965333,DB0009910003549_,0.635532582,0.168457338,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,filgrastim,DB00099
,79056,DB00115,10027175,302,18123,99,10373,7.77352486992837e-07,1.745974952,1.385109302,2.216718171,1.14693854171242e-05,DB0011510027175_,11.37582921,0.557313111,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,79057,DB00836,10027175,51,5484,20,4055,0.015639571,1.88540313,1.102434288,3.3442123,0.05094004,DB0083610027175_,2.97710602,0.63414166,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,79068,DB08877,10046306,25,3264,30,3199,0.49963308,0.816765026,0.459513029,1.44023105,0.661372159,DB0887710046306_,0.413438574,-0.202403831,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,ruxolitinib,DB08877
,79069,DB00230,10033664,77,19597,19,8632,0.025760432,1.785052945,1.068808645,3.126300726,0.075167958,DB0023010033664_,2.58803023,0.579448076,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,79073,DB13961,10022061,114,9343,25,6389,1.5885537209907e-08,3.118031236,2.006085454,5.024932952,3.40580216608813e-07,DB1396110022061_,14.89261515,1.137201789,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,79074,DB13961,10022093,73,9384,16,6398,6.71025400563376e-06,3.110488466,1.791231989,5.730669922,7.65700136913755e-05,DB1396110022093_,9.477305024,1.134779777,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,79084,DB00758,10022052,91,8209,44,10030,2.05557675699208e-07,2.526850602,1.742255654,3.713032593,3.4768877128402e-06,DB0075810022052_,12.569373,0.926973706,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,79085,DB06285,10022052,172,8678,10,1096,0.012042168,2.172174069,1.148260808,4.625471622,0.041254923,DB0628510022052_,3.187984828,0.775728541,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,79087,DB06285,10033371,346,8504,26,1080,0.008901242,1.689987924,1.12690362,2.637238584,0.032428158,DB0628510033371_,3.428728173,0.524721384,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,79090,DB00264,10062519,48,29559,22,24870,0.016470686,1.835670282,1.086564245,3.194526727,0.053016409,DB0026410062519_,2.937153814,0.607409691,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,79094,DB05679,10004146,19,6912,33,4876,0.001680075,0.406191366,0.217960951,0.736583257,0.008431653,DB0567910004146_,4.775762497,-0.900930886,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ustekinumab,DB05679
,79106,DB11093,10013968,67,1590,21,639,0.399168478,1.282048642,0.767644264,2.223681441,0.569019115,DB1109310013968_,0.563841252,0.2484593,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium citrate,DB11093
,79108,DB00959,10016334,37,8041,19,4983,0.582332054,1.206727666,0.675550765,2.224167294,0.730485732,DB0095910016334_,0.31404558,0.187912288,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,79111,DB00281,10040829,44,11414,8,5663,0.007181601,2.72866536,1.26951247,6.715462586,0.027331353,DB0028110040829_,3.599720789,1.003812611,female,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,lidocaine,DB00281
,79117,DB00470,10011906,68,851,88,865,0.155897982,0.785542884,0.555629158,1.106756907,0.291999748,DB0047010011906_,1.23100234,-0.241380228,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dronabinol,DB00470
,79122,DB00482,10003246,114,8145,31,3040,0.132356457,1.3724705,0.913583632,2.117647993,0.259100263,DB0048210003246_,1.350540178,0.3166124,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,79124,DB00178,10013700,131,1306,40,1640,9.85515196914275e-17,4.110801277,2.841755451,6.059644234,7.34872821301893e-15,DB0017810013700_,32.54424913,1.413617967,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ramipril,DB00178
,79125,DB00887,10013700,40,2301,19,1796,0.085443527,1.643030904,0.925906988,3.01465295,0.187441215,DB0088710013700_,1.674290004,0.496542648,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,bumetanide,DB00887
,79130,DB00555,10013950,45,7002,17,3469,0.416841618,1.311440958,0.73469402,2.447747091,0.586028504,DB0055510013950_,0.534386849,0.2711265,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,lamotrigine,DB00555
,79132,DB00555,10015150,53,6994,10,3476,0.002885554,2.633885359,1.323986977,5.813252571,0.013092834,DB0055510015150_,4.335690213,0.968460079,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,lamotrigine,DB00555
,79133,DB00656,10015150,101,11912,28,6591,0.000829686,1.995792115,1.300512337,3.155013808,0.004719389,DB0065610015150_,5.356076026,0.691041022,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,trazodone,DB00656
,79139,DB00656,10042128,54,11959,19,6600,0.110470094,1.568481411,0.914023476,2.804575295,0.226763484,DB0065610042128_,1.483847723,0.450107897,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,79144,DB00656,10049414,43,11970,25,6594,0.899079116,0.947511997,0.565206518,1.620380274,0.956490275,DB0065610049414_,0.044484657,-0.053915681,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,79145,DB01156,10049414,31,13591,20,6308,0.291107146,0.719398048,0.396814245,1.332891536,0.456507551,DB0115610049414_,0.784150037,-0.329340462,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,79147,DB01273,10037844,45,1995,30,1245,0.810716678,0.93610956,0.573466439,1.5477647,0.898205372,DB0127310037844_,0.107356538,-0.066022758,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,varenicline,DB01273
,79152,DB00635,10022094,138,32915,18,23776,1.33265272402468e-16,5.537842788,3.375591222,9.624365705,9.81198231120131e-15,DB0063510022094_,32.25517207,1.711605036,female,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,79153,DB01373,10022094,41,22679,10,7371,0.515139694,1.332532506,0.656011196,2.984997831,0.674980527,DB0137310022094_,0.393071437,0.287081271,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,79154,DB00005,10059176,111,127971,34,42385,0.773205811,1.081295321,0.730373764,1.638424901,0.876003307,DB0000510059176_,0.132385412,0.078159693,NA,10059176,Juvenile idiopathic arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,79161,DB00188,10028334,127,7759,115,8713,0.104832095,1.240111758,0.954090859,1.613297023,0.218236564,DB0018810028334_,1.522175647,0.215201503,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,bortezomib,DB00188
,79162,DB00188,10040829,51,7835,36,8792,0.040196685,1.589645037,1.016230977,2.510252638,0.106070661,DB0018810040829_,2.243649795,0.463510744,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,bortezomib,DB00188
,79163,DB00480,10040829,571,66857,268,67394,1.84650195225719e-26,2.147686984,1.853634676,2.493338915,3.17224207941701e-24,DB0048010040829_,54.10760361,0.764391442,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,79174,DB00916,10046735,100,5223,29,2402,0.027817188,1.585737999,1.036472852,2.494988906,0.079809504,DB0091610046735_,2.528112679,0.461049914,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,metronidazole,DB00916
,79190,DB00051,10037575,54,25677,14,11406,0.086245822,1.713362159,0.938112099,3.341290868,0.188764847,DB0005110037575_,1.667253233,0.538457615,NA,10037575,Pustular psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,79225,DB01240,10021143,195,5556,68,1508,0.092275492,0.778360398,0.584022204,1.047785358,0.198857203,DB0124010021143_,1.615168283,-0.250565625,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,79226,DB01240,10074414,355,5396,112,1464,0.180874927,0.860009545,0.687766166,1.081774405,0.324991281,DB0124010074414_,1.123956925,-0.150811791,NA,10074414,Catheter management,10042613,Surgical and medical procedures,Surg,epoprostenol,DB01240
,79232,DB00281,10005750,83,11375,55,5616,0.101805433,0.745043855,0.522756671,1.069230526,0.213649165,DB0028110005750_,1.543420023,-0.294312197,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,lidocaine,DB00281
,79235,DB00586,10005750,62,7047,23,2782,0.903836554,1.064176931,0.648501916,1.803621391,0.95743432,DB0058610005750_,0.043498156,0.062201666,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,diclofenac,DB00586
,79244,DB00218,10012735,68,1374,22,928,0.002826321,2.087005706,1.263549857,3.572078841,0.01287191,DB0021810012735_,4.352707853,0.735730362,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,moxifloxacin,DB00218
,79245,DB00465,10012735,51,2053,24,859,0.611071999,0.889168701,0.533375908,1.52078369,0.753148782,DB0046510012735_,0.283492485,-0.117468296,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ketorolac,DB00465
,79249,DB15566,10012735,44,963,21,641,0.245342017,1.394381017,0.802760456,2.49355631,0.404137051,DB1556610012735_,0.906001224,0.332450601,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,prednisolone acetate,DB15566
,79250,DB00654,10015946,181,3635,85,2513,0.004020641,1.472048448,1.125430422,1.93792124,0.017154863,DB0065410015946_,4.065473568,0.386654933,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,latanoprost,DB00654
,79253,DB00654,10022806,73,3743,54,2544,0.648897884,0.918824447,0.635027936,1.336519528,0.783836438,DB0065410022806_,0.243554906,-0.084660201,NA,10022806,Intraocular pressure increased,10022891,Investigations,Inv,latanoprost,DB00654
,79258,DB00654,10030041,92,3724,31,2567,0.000395753,2.045482209,1.34360049,3.190500437,0.002539642,DB0065410030041_,5.975732025,0.715633561,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,latanoprost,DB00654
,79262,DB00281,10047571,66,11392,30,5641,0.745164662,1.089370746,0.696533764,1.739958559,0.854485157,DB0028110047571_,0.157256147,0.085600232,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,lidocaine,DB00281
,79298,DB00108,10030901,209,9985,64,3231,0.77591128,1.056684832,0.792637443,1.425134303,0.877822795,DB0010810030901_,0.130310533,0.05513649,NA,10030901,Opportunistic infection,10021881,Infections and infestations,Infec,natalizumab,DB00108
,79301,DB01267,10002855,32,2820,58,3657,0.135072778,0.715516964,0.448278175,1.12378511,0.262786188,DB0126710002855_,1.336414552,-0.334749971,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,79346,DB08908,10050584,62,10611,6,3273,0.002448712,3.187253409,1.382471565,9.025410892,0.011476224,DB0890810050584_,4.46747782,1.159159546,female,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,dimethyl fumarate,DB08908
,79347,DB08908,10047899,59,10614,10,3269,0.087151108,1.817004486,0.920501556,3.989375775,0.190334167,DB0890810047899_,1.658973978,0.597189258,NA,10047899,Weight increased,10022891,Investigations,Inv,dimethyl fumarate,DB08908
,79352,DB06674,10012735,93,4413,29,1461,0.832983936,1.061679613,0.689901235,1.678551634,0.913108941,DB0667410012735_,0.090900083,0.059852194,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,golimumab,DB06674
,79353,DB00563,10043255,45,46601,7,15341,0.075239123,2.116126691,0.947091713,5.562998,0.170236378,DB0056310043255_,1.770567349,0.749587385,NA,10043255,Tendonitis,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,79354,DB00563,10043607,79,46567,48,15300,0.001291093,0.540777153,0.372889174,0.791438859,0.006787953,DB0056310043607_,4.99260582,-0.614748002,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,methotrexate,DB00563
,79355,DB00737,10000059,45,2756,13,919,0.760383347,1.154219206,0.60857158,2.343041807,0.866851465,DB0073710000059_,0.142887637,0.143424103,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,meclizine,DB00737
,79356,DB00737,10013573,213,2588,68,864,0.82977098,1.045698119,0.783143397,1.410425532,0.91066932,DB0073710013573_,0.093575433,0.044684718,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,meclizine,DB00737
,79357,DB00181,10017885,43,9813,16,5855,0.107767942,1.603471279,0.884032873,3.052521519,0.222712505,DB0018110017885_,1.501873553,0.472170829,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,baclofen,DB00181
,79359,DB08908,10017885,58,10615,11,3268,0.155471239,1.623202366,0.84233125,3.434141691,0.291454552,DB0890810017885_,1.232871196,0.484400967,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,dimethyl fumarate,DB08908
,79360,DB00737,10021097,47,2754,32,900,0.002262608,0.480079838,0.297895211,0.782672741,0.010756134,DB0073710021097_,4.532279126,-0.733802859,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,meclizine,DB00737
,79361,DB01240,10003239,274,5477,83,1493,0.428005414,0.899889236,0.696524129,1.172643395,0.596507015,DB0124010003239_,0.516664278,-0.105483594,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,epoprostenol,DB01240
,79373,DB00153,10053762,228,7195,98,3341,0.546086282,1.080315788,0.845714558,1.388394222,0.700742839,DB0015310053762_,0.355614307,0.077253395,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ergocalciferol,DB00153
,79391,DB00193,10001760,224,19096,16,8686,3.1594593136891e-20,6.368044763,3.832615299,11.34371858,3.32851254750773e-18,DB0019310001760_,40.24400615,1.851292478,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,79394,DB01156,10001760,145,13477,10,6318,2.39598694693009e-14,6.797462755,3.588413233,14.49116279,1.33712350106279e-12,DB0115610001760_,27.34050045,1.916549418,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,bupropion,DB01156
,79395,DB00423,10003239,72,2395,16,1024,0.017612872,1.923697961,1.10143819,3.56165267,0.055946143,DB0042310003239_,2.883365778,0.654249355,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,methocarbamol,DB00423
,79396,DB00433,10003239,154,7502,77,5943,0.001017188,1.584322851,1.194787496,2.115388069,0.0055832,DB0043310003239_,5.187993221,0.460157093,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,prochlorperazine,DB00433
,79397,DB00656,10003239,305,11708,96,6523,6.239105137523e-07,1.770030755,1.399825906,2.254955763,9.43041279699782e-06,DB0065610003239_,11.57157069,0.570996922,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,79398,DB00285,10010774,161,10790,45,3673,0.259616574,1.217880565,0.868230961,1.738730011,0.420768383,DB0028510010774_,0.865672755,0.197112106,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,79399,DB00788,10010774,176,9180,89,4972,0.649427407,1.071054358,0.823335596,1.401473631,0.784277843,DB0078810010774_,0.24299193,0.068643544,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,79400,DB00285,10013496,58,10893,11,3707,0.072582492,1.79420434,0.931207222,3.79600988,0.16581182,DB0028510013496_,1.796901747,0.584561659,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,79403,DB00656,10013496,43,11970,19,6600,0.506615727,1.247884843,0.711077963,2.269301969,0.667337913,DB0065610013496_,0.404458745,0.221449993,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,79406,DB01156,10013496,87,13535,30,6298,0.164311352,1.34943058,0.880839295,2.11975729,0.303188761,DB0115610013496_,1.193399694,0.299682711,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,79407,DB00423,10013573,56,2411,31,1009,0.234560418,0.756044417,0.475877472,1.221063208,0.391449575,DB0042310013573_,0.937898573,-0.279655151,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,methocarbamol,DB00423
,79408,DB00193,10013786,91,19229,25,8677,0.026813145,1.642507354,1.044590724,2.671470412,0.077585151,DB0019310013786_,2.556379227,0.496223949,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,79412,DB00656,10013786,36,11977,19,6600,1,1.044106523,0.582717816,1.928647705,1,DB0065610013786_,0,0.043161518,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,trazodone,DB00656
,79413,DB01069,10013786,51,6649,10,2385,0.08097141,1.829340032,0.916382968,4.047850854,0.180001724,DB0106910013786_,1.714788852,0.603955263,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,promethazine,DB01069
,79414,DB01156,10013786,50,13572,17,6311,0.294607779,1.36767208,0.774671844,2.531751986,0.460458777,DB0115610013786_,0.775531945,0.313110083,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,bupropion,DB01156
,79415,DB00193,10013946,117,19203,31,8671,0.0073616,1.704185443,1.137647689,2.622680069,0.027873764,DB0019310013946_,3.580069407,0.533087251,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,79416,DB00285,10013946,67,10884,11,3707,0.025523553,2.074537876,1.086858097,4.358123143,0.074663247,DB0028510013946_,2.594767321,0.729738419,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,79418,DB00433,10013946,54,7602,29,5991,0.097427451,1.467420876,0.916649461,2.393332555,0.207015121,DB0043310013946_,1.574963439,0.383506354,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,79420,DB00656,10013946,68,11945,14,6605,0.000294424,2.685635405,1.494737244,5.17416207,0.001987146,DB0065610013946_,6.221055969,0.98791735,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,79421,DB01069,10013946,63,6637,17,2378,0.37183487,1.32773618,0.765510701,2.425575069,0.541493091,DB0106910013946_,0.613424972,0.283475372,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,promethazine,DB01069
,79422,DB01156,10013946,67,13555,22,6306,0.171405409,1.416794985,0.863031214,2.411500606,0.312765787,DB0115610013946_,1.162300653,0.348397268,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,79434,DB00433,10020772,99,7557,71,5949,0.586674504,1.097693287,0.799501994,1.513587576,0.733866623,DB0043310020772_,0.30942798,0.093210966,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,prochlorperazine,DB00433
,79442,DB00423,10022437,60,2407,27,1013,0.812209261,0.935254932,0.580710362,1.541861363,0.89905753,DB0042310022437_,0.106408254,-0.066936132,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,methocarbamol,DB00423
,79453,DB00285,10025482,323,10628,69,3649,0.000253925,1.607250558,1.232172562,2.12152701,0.001758974,DB0028510025482_,6.34302439,0.474524991,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,79454,DB00423,10025482,73,2394,26,1014,0.503982914,1.189153705,0.745617,1.951127194,0.665103095,DB0042310025482_,0.40781322,0.173241882,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,methocarbamol,DB00423
,79455,DB00656,10025482,383,11630,120,6499,1.2536075948226e-08,1.783494116,1.445696854,2.213282053,2.75972157704457e-07,DB0065610025482_,15.10296585,0.578574427,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,79456,DB01156,10025482,323,13299,69,6259,2.0980948517453e-10,2.203051518,1.690859179,2.905163749,6.50335178987325e-09,DB0115610025482_,18.85094813,0.789843453,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,79457,DB00193,10027175,226,19094,53,8649,6.38250315048378e-06,1.931490656,1.424885784,2.65995935,7.32754292686029e-05,DB0019310027175_,9.521285213,0.658292066,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,79458,DB00285,10027175,148,10803,38,3680,0.127223096,1.326684291,0.921457814,1.952257003,0.251757622,DB0028510027175_,1.379288473,0.282682815,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,79459,DB00423,10027175,38,2429,18,1022,0.660646855,0.888286604,0.491945896,1.661796349,0.792837988,DB0042310027175_,0.232136381,-0.118460836,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,methocarbamol,DB00423
,79460,DB00433,10027175,60,7596,32,5988,0.074262471,1.478037162,0.945585158,2.349406876,0.168625412,DB0043310027175_,1.78007552,0.390714966,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,79461,DB00788,10027175,120,9236,33,5028,0.000322055,1.979520895,1.334629812,3.010205895,0.002138223,DB0078810027175_,6.147780289,0.682854843,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,79462,DB00193,10033557,123,19197,17,8685,1.97731741553901e-07,3.273067956,1.961512989,5.804980737,3.35856466994784e-06,DB0019310033557_,12.60399686,1.185727758,female,10033557,Palpitations,10007541,Cardiac disorders,Card,tramadol,DB00193
,79465,DB00656,10033557,107,11906,20,6599,9.20590450898373e-07,2.965134095,1.825579353,5.053075749,1.33210679889148e-05,DB0065610033557_,11.22616372,1.086922258,female,10033557,Palpitations,10007541,Cardiac disorders,Card,trazodone,DB00656
,79466,DB00788,10033557,58,9298,12,5049,0.001492029,2.624443242,1.392439577,5.373945756,0.007656022,DB0078810033557_,4.872262807,0.964868775,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,naproxen,DB00788
,79467,DB01069,10033557,52,6648,7,2388,0.010912402,2.66835611,1.205039292,6.972775088,0.038175616,DB0106910033557_,3.265558287,0.981462594,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,promethazine,DB01069
,79468,DB00193,10039101,112,19208,20,8682,4.11473948613861e-05,2.53112512,1.56221612,4.305042928,0.000373596,DB0019310039101_,7.892336618,0.928663915,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,79471,DB00433,10039101,44,7612,18,6002,0.020353307,1.927318295,1.089800254,3.547724836,0.062659485,DB0043310039101_,2.770040215,0.656129552,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,79473,DB00656,10039101,51,11962,19,6600,0.168548732,1.480976122,0.858561206,2.658638887,0.308967723,DB0065610039101_,1.174518462,0.392701412,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,79474,DB00788,10039101,58,9298,18,5043,0.040090945,1.747589696,1.013736981,3.155522569,0.105866034,DB0078810039101_,2.245580817,0.558237522,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,naproxen,DB00788
,79475,DB01069,10039101,42,6658,8,2387,0.108006023,1.882170499,0.871272008,4.648640502,0.223066654,DB0106910039101_,1.500284655,0.632425632,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,promethazine,DB01069
,79476,DB01156,10039101,44,13578,14,6314,0.258525269,1.461466059,0.785338083,2.889810715,0.419568825,DB0115610039101_,0.868527703,0.379440082,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,79499,DB00285,10046306,53,10898,11,3707,0.15055839,1.638808766,0.844935432,3.483402385,0.284737726,DB0028510046306_,1.256186782,0.493969616,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,venlafaxine,DB00285
,79500,DB00404,10046306,135,19757,35,9827,0.000407665,1.918479459,1.313269168,2.870356781,0.002604322,DB0040410046306_,5.950582968,0.651532924,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,alprazolam,DB00404
,79502,DB00433,10046306,62,7594,29,5991,0.019693495,1.686575227,1.067154655,2.723048933,0.061064472,DB0043310046306_,2.795825058,0.52269998,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,79504,DB00656,10046306,71,11942,23,6596,0.030088886,1.704992717,1.05125867,2.862790465,0.084890932,DB0065610046306_,2.466388003,0.533560839,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,trazodone,DB00656
,79505,DB01069,10046306,80,6620,11,2384,0.001156253,2.619049923,1.384846618,5.465729003,0.006211192,DB0106910046306_,5.081402404,0.962811627,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,promethazine,DB01069
,79506,DB01156,10046306,78,13544,14,6314,0.000434592,2.597209425,1.457724745,4.973091794,0.002746967,DB0115610046306_,5.897258014,0.95443757,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,bupropion,DB01156
,79507,DB00423,10047700,68,2399,25,1015,0.645460951,1.150761202,0.713193389,1.911681752,0.78117292,DB0042310047700_,0.246958745,0.140423638,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,methocarbamol,DB00423
,79508,DB00193,10047924,78,19242,15,8687,0.001515939,2.347534376,1.338770292,4.396143726,0.007760795,DB0019310047924_,4.85867056,0.853365576,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,79512,DB00656,10047924,46,11967,11,6608,0.011852044,2.309046475,1.177172559,4.947681702,0.040770971,DB0065610047924_,3.199784949,0.836834658,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,79527,DB00158,10017955,90,16725,78,8026,0.000182618,0.553693119,0.403840779,0.760673113,0.001335959,DB0015810017955_,6.618105811,-0.591144683,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,79529,DB01222,10017955,51,9223,62,5343,0.000113608,0.476547982,0.321891179,0.702764978,0.00089047,DB0122210017955_,7.023761626,-0.741186864,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,79534,DB01076,10013710,177,25570,188,25395,0.528909511,0.935018481,0.756605235,1.155206633,0.686232612,DB0107610013710_,0.376538624,-0.067188984,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,79538,DB08895,10050584,244,27870,42,6604,0.058829225,1.376591896,0.987803525,1.960716971,0.141262156,DB0889510050584_,1.957137852,0.319610804,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,79539,DB00635,10051017,27,33026,47,23747,0.000213244,0.413069335,0.247291241,0.677201095,0.001519825,DB0063510051017_,6.489160156,-0.884139818,NA,10051017,Staphylococcal bacteraemia,10021881,Infections and infestations,Infec,prednisone,DB00635
,79542,DB00787,10000087,162,16838,100,17148,8.67554265183517e-05,1.649790518,1.276735959,2.140682734,0.000706543,DB0078710000087_,7.255126997,0.500648321,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,79545,DB00230,10029410,62,19612,21,8630,0.340532135,1.299107732,0.780370192,2.245404036,0.509731616,DB0023010029410_,0.673870935,0.261677669,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,79546,DB00787,10029410,39,16961,32,17216,0.406557414,1.237063107,0.754823859,2.040789791,0.576153073,DB0078710029410_,0.551381902,0.212740108,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,79547,DB13961,10029410,33,9424,22,6392,1,1.01740206,0.575055118,1.833514964,1,DB1396110029410_,0,0.017252378,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,fish oil,DB13961
,79548,DB00814,10003239,355,7932,103,3312,0.001133774,1.439111466,1.147900581,1.816920336,0.006106813,DB0081410003239_,5.098350235,0.364025886,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,79552,DB00814,10016173,243,8044,89,3326,0.358470374,1.128912908,0.878809598,1.46090083,0.528169626,DB0081410016173_,0.638337786,0.121255142,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,meloxicam,DB00814
,79553,DB00814,10017955,38,8249,48,3367,2.66207561453498e-07,0.32317106,0.205027466,0.506138774,4.38837613847927e-06,DB0081410017955_,12.3365513,-1.129573498,male,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,79554,DB00005,10018836,64,128018,44,42375,0.00031247,0.481453493,0.322876658,0.72379942,0.002086974,DB0000510018836_,6.172040248,-0.73094564,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,79570,DB00814,10048334,58,8229,13,3402,0.048785188,1.844387578,0.997191412,3.674288633,0.122771403,DB0081410048334_,2.097431165,0.612147286,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,79571,DB01611,10048334,79,11834,18,2343,0.583401298,0.868986717,0.514748021,1.54409601,0.731448741,DB0161110048334_,0.312728135,-0.140427439,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,79576,DB00814,10052904,89,8198,40,3375,0.627693927,0.916011506,0.622549488,1.368763693,0.767039846,DB0081410052904_,0.265216529,-0.087726353,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,79592,DB00047,10014625,31,9254,19,8499,0.20171287,1.49842564,0.819447114,2.809587074,0.3511152,DB0004710014625_,1.046640903,0.404414984,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,79600,DB00190,10021097,86,3211,116,4558,0.718227326,1.052353056,0.783819651,1.408439129,0.833604562,DB0019010021097_,0.181996135,0.051028663,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,carbidopa,DB00190
,79602,DB01065,10021097,81,4250,73,2978,0.136450695,0.777530876,0.557552716,1.085827983,0.264713744,DB0106510021097_,1.329106246,-0.251631924,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,melatonin,DB01065
,79631,DB00451,10019022,73,47198,20,15399,0.548033324,1.19085592,0.717799763,2.063109185,0.702539216,DB0045110019022_,0.353054056,0.174672309,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,79634,DB01076,10019022,33,25714,25,25558,0.358013585,1.311981152,0.756532599,2.302093425,0.527739511,DB0107610019022_,0.639152468,0.271538324,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,79643,DB00586,10046571,136,6973,22,2783,2.37726119146805e-05,2.46701826,1.561003279,4.075804036,0.000231345,DB0058610046571_,8.37160004,0.903010239,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,diclofenac,DB00586
,79644,DB00678,10046571,356,15243,89,10635,8.88171877572127e-21,2.790644006,2.203271842,3.566068458,1.01502599139058e-18,DB0067810046571_,41.43161745,1.026272396,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,losartan,DB00678
,79646,DB00370,10048294,36,4505,42,3621,0.109498266,0.688988615,0.427929405,1.104253514,0.22532289,DB0037010048294_,1.490220841,-0.372530533,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,mirtazapine,DB00370
,79648,DB00588,10048294,68,16456,28,8440,0.387473891,1.245522163,0.790555501,2.011047294,0.557533939,DB0058810048294_,0.584231901,0.21955485,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,79676,DB00190,10061422,47,3250,135,4539,1.23218330987328e-05,0.486273235,0.340151921,0.684714862,0.000130362,DB0019010061422_,8.945197567,-0.720984602,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,79678,DB00860,10025482,51,1832,28,1468,0.135778715,1.459367625,0.897896893,2.416535773,0.263770261,DB0086010025482_,1.332676777,0.378003209,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,prednisolone,DB00860
,79679,DB00682,10020993,54,19405,41,16323,0.68033693,1.10785508,0.724159567,1.706395888,0.806615074,DB0068210020993_,0.214908708,0.102425785,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,79680,DB00996,10020993,95,38858,60,22365,0.616418714,0.911301966,0.65247037,1.28148047,0.757571754,DB0099610020993_,0.277637021,-0.09288097,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,79682,DB00564,10016173,98,2506,54,1409,0.93159364,1.020376376,0.719670049,1.459748532,0.972587046,DB0056410016173_,0.0277957,0.020171555,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,carbamazepine,DB00564
,79683,DB00482,10044565,63,8196,26,3045,0.633634359,0.900244059,0.56057992,1.484323236,0.772140897,DB0048210044565_,0.258588237,-0.105089376,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,79689,DB00515,10029366,61,1809,46,2105,0.030490948,1.54288556,1.029325028,2.326698714,0.08575834,DB0051510029366_,2.456221936,0.433654403,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,cisplatin,DB00515
,79692,DB00441,10047942,39,2235,29,1865,0.713062203,1.122141624,0.673390458,1.88943474,0.829586156,DB0044110047942_,0.18682831,0.115239024,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,gemcitabine,DB00441
,79693,DB00515,10047942,47,1823,52,2099,0.91880979,1.040693977,0.682608276,1.58295012,0.964146885,DB0051510047942_,0.036511626,0.039887777,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,cisplatin,DB00515
,79696,DB08880,10000087,56,3282,11,798,0.641109956,1.237763918,0.637890752,2.632574442,0.777943746,DB0888010000087_,0.251101063,0.21330646,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,teriflunomide,DB08880
,79698,DB08880,10028334,57,3281,10,799,0.436582661,1.387975876,0.698543244,3.062707662,0.605156106,DB0888010028334_,0.502268827,0.327846481,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,teriflunomide,DB08880
,79700,DB00115,10022061,168,18257,27,10445,3.63332295952774e-12,3.559661882,2.359458104,5.566180744,1.48756844223032e-10,DB0011510022061_,22.62870806,1.269665563,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,79701,DB00641,10022061,77,14047,22,12453,4.70794343007201e-07,3.102537608,1.909599664,5.238570829,7.35065595838686e-06,DB0064110022061_,11.820721,1.13222036,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,79702,DB00814,10022061,116,8171,20,3395,8.99750930359746e-05,2.409717494,1.487817205,4.097730732,0.000729599,DB0081410022061_,7.223015421,0.879509518,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,79703,DB00115,10022093,96,18329,12,10460,4.42778626858354e-09,4.565021595,2.495110941,9.147895604,1.07663609685216e-07,DB0011510022093_,16.0442542,1.518423245,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,79704,DB00641,10022093,46,14078,13,12462,0.000113681,3.131993713,1.662965233,6.322425699,0.000890876,DB0064110022093_,7.023305344,1.141669771,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,79705,DB00814,10022093,66,8221,9,3406,0.000525621,3.037794957,1.50491135,6.942933941,0.003217125,DB0081410022093_,5.739267109,1.111131909,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,79706,DB00115,10022095,120,18305,22,10450,5.67347487118204e-08,3.113795348,1.963496589,5.157502585,1.0829868336167e-06,DB0011510022095_,13.73578775,1.135842351,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,79707,DB00641,10022095,50,14074,23,12452,0.009404777,1.923322479,1.15122942,3.304367081,0.033889171,DB0064110022095_,3.384659766,0.654054148,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,79708,DB00814,10022095,74,8213,14,3401,0.004636615,2.188690652,1.22373257,4.202740159,0.019242665,DB0081410022095_,3.950625316,0.783303489,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,79709,DB01075,10022095,77,19871,19,11078,0.000862923,2.259271081,1.352887057,3.956228275,0.004877836,DB0107510022095_,5.323053579,0.815042231,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,79710,DB00115,10053425,99,18326,16,10456,1.43947572007648e-07,3.53018488,2.06847607,6.419151438,2.52834074856066e-06,DB0011510053425_,12.8879473,1.261350243,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,79711,DB00641,10053425,52,14072,16,12459,8.21141642286679e-05,2.877215753,1.616129143,5.402561864,0.000674282,DB0064110053425_,7.301862054,1.056823074,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,79712,DB01075,10053425,97,19851,17,11080,1.05471067016372e-06,3.184683347,1.88874163,5.692764967,1.49976034434694e-05,DB0107510053425_,11.10762014,1.158352864,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,79720,DB08880,10027175,72,3266,21,788,0.429062141,0.827264253,0.49926699,1.425638429,0.597567868,DB0888010027175_,0.514887415,-0.189631104,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,teriflunomide,DB08880
,79733,DB00588,10036495,37,16487,13,8455,0.295257299,1.459567448,0.75778053,2.994137676,0.461174359,DB0058810036495_,0.773979088,0.378140123,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,79735,DB09140,10053762,86,3655,43,1755,0.849256446,0.960346147,0.655308362,1.425574998,0.924967604,DB0914010053762_,0.077996565,-0.040461489,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,oxygen,DB09140
,79739,DB00005,10018735,70,128012,18,42401,0.38870843,1.288091185,0.758703638,2.298530997,0.558598223,DB0000510018735_,0.582324807,0.253161421,NA,10018735,Groin pain,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,79740,DB00331,10057668,55,24891,36,20716,0.292374054,1.27151366,0.819983108,1.99352535,0.45794786,DB0033110057668_,0.780999944,0.240208049,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,metformin,DB00331
,79742,DB01076,10057668,54,25693,80,25503,0.024327921,0.670017152,0.465200661,0.958537294,0.072019305,DB0107610057668_,2.630821076,-0.400451967,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,79755,DB01068,10013496,86,13677,33,6807,0.241205136,1.297057255,0.857958207,2.003049264,0.399358334,DB0106810013496_,0.917896185,0.260098048,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,79767,DB00734,10014551,6,4044,47,4855,1.91677612730216e-07,0.153285355,0.053505692,0.35974305,3.26840483335304e-06,DB0073410014551_,12.63120851,-1.875454032,male,10014551,Emotional disorder,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,79772,DB00734,10024264,24,4026,39,4863,0.309568932,0.743347532,0.426838494,1.269971452,0.477006735,DB0073410024264_,0.740224669,-0.296591603,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,79773,DB01068,10024264,95,13668,52,6788,0.598152479,0.907320313,0.639512553,1.299737369,0.743026367,DB0106810024264_,0.297023748,-0.097259735,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,79776,DB00734,10033371,56,3994,32,4870,0.000533658,2.133664153,1.355060614,3.411761077,0.003255705,DB0073410033371_,5.727346325,0.757840761,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,79777,DB00175,10010305,93,8038,74,6032,0.753202165,0.943136514,0.686154374,1.300212422,0.861097314,DB0017510010305_,0.149547757,-0.058544241,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,pravastatin,DB00175
,79780,DB01068,10010305,203,13560,139,6701,0.003749595,0.721694362,0.577547837,0.903951602,0.016191572,DB0106810010305_,4.123264401,-0.326153551,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,79786,DB01060,10013710,30,8557,59,5022,2.8899842394873e-08,0.298444968,0.185339885,0.47148373,5.85458464238332e-07,DB0106010013710_,14.3508706,-1.209169725,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,79791,DB01060,10021143,25,8562,30,5051,0.011124251,0.491626756,0.276902916,0.865853424,0.038751628,DB0106010021143_,3.250582523,-0.710035477,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amoxicillin,DB01060
,79795,DB09053,10038435,18,2267,49,4003,0.125727045,0.648691619,0.354750871,1.136851376,0.249673445,DB0905310038435_,1.387601435,-0.432797839,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,ibrutinib,DB09053
,79796,DB00073,10045170,20,7386,95,6312,1.36129160998011e-15,0.179948755,0.105055317,0.294108924,9.01298487867186e-14,DB0007310045170_,30.037525,-1.715083164,male,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,rituximab,DB00073
,79799,DB00437,10061818,81,6840,171,11375,0.088262476,0.787769495,0.596059755,1.033904995,0.1923538,DB0043710061818_,1.648418894,-0.238549751,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,79801,DB01234,10007617,50,31575,87,32801,0.003530243,0.597035466,0.412798224,0.855307833,0.015425602,DB0123410007617_,4.171726673,-0.515778761,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,79804,DB01234,10047571,142,31483,103,32785,0.005801413,1.435639374,1.105593984,1.869645839,0.02304869,DB0123410047571_,3.770146341,0.361610306,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,dexamethasone,DB01234
,79809,DB00169,10033647,54,38637,31,18144,0.415114788,0.818037695,0.516346692,1.316885976,0.584365341,DB0016910033647_,0.537228908,-0.200846861,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,79814,DB00230,10019063,95,19579,51,8600,0.243079816,0.818231997,0.575677078,1.174697646,0.401379085,DB0023010019063_,0.912848949,-0.200609367,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,79816,DB00005,10034835,111,127971,24,42395,0.058411477,1.532152913,0.978649366,2.491930644,0.140522209,DB0000510034835_,1.962389729,0.426673879,NA,10034835,Pharyngitis,10021881,Infections and infestations,Infec,etanercept,DB00005
,79819,DB00745,10046571,96,2481,27,1056,0.06993621,1.51321114,0.971838745,2.428279926,0.161188414,DB0074510046571_,1.825181323,0.414233976,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,modafinil,DB00745
,79820,DB00915,10046571,106,1349,31,1020,1.7673895321342e-06,2.584483565,1.701964459,4.025293755,2.37382901646129e-05,DB0091510046571_,10.64842119,0.949525707,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,amantadine,DB00915
,79821,DB00213,10022095,58,18837,17,13404,0.000894303,2.427655821,1.393371903,4.449124009,0.00502496,DB0021310022095_,5.293337838,0.886926109,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,79828,DB00112,10000059,56,5877,35,4056,0.669874071,1.104250087,0.709721008,1.739318798,0.799729298,DB0011210000059_,0.223481986,0.099166451,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,79834,DB01101,10000059,79,7510,31,3877,0.224907834,1.31558952,0.856538916,2.066515977,0.379683693,DB0110110000059_,0.96841676,0.274284869,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,79835,DB01234,10000059,244,31381,191,32697,0.003297747,1.331048656,1.096182499,1.618108976,0.014606331,DB0123410000059_,4.226300183,0.285967094,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,79836,DB00377,10000081,75,1044,31,692,0.031390682,1.603242985,1.029201402,2.550259676,0.087758358,DB0037710000081_,2.433168178,0.472028443,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,palonosetron,DB00377
,79844,DB00722,10001488,29,25374,53,25979,0.011050442,0.560225417,0.343328038,0.897565261,0.038535439,DB0072210001488_,3.256176959,-0.579416046,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,79865,DB00002,10011906,44,372,48,761,0.0041969,1.874262111,1.192359859,2.940306642,0.017759292,DB0000210011906_,4.0308464,0.628215041,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cetuximab,DB00002
,79866,DB00762,10011906,212,951,254,1115,0.837151609,0.978585314,0.795325063,1.203333957,0.916034804,DB0076210011906_,0.087700919,-0.021647307,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,irinotecan,DB00762
,79889,DB00722,10012374,59,25344,33,25999,0.004754451,1.834051694,1.177782539,2.900650292,0.019641766,DB0072210012374_,3.930097081,0.60652756,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,79893,DB00999,10012374,56,21374,20,12219,0.07360512,1.600670985,0.945123232,2.817618253,0.167524399,DB0099910012374_,1.786626272,0.470422907,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,79897,DB00002,10012735,25,391,34,775,0.161933081,1.45700314,0.820764437,2.555040352,0.299988662,DB0000210012735_,1.204010599,0.376381682,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cetuximab,DB00002
,79898,DB00377,10012735,120,999,82,641,0.702844864,0.93902048,0.690455052,1.281785742,0.821706817,DB0037710012735_,0.196371618,-0.062917989,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,palonosetron,DB00377
,79899,DB00889,10012735,73,707,46,471,0.844390004,1.057187714,0.707000526,1.593946473,0.921373327,DB0088910012735_,0.081889975,0.055612282,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,granisetron,DB00889
,79900,DB00526,10016256,101,1497,129,1765,0.584218682,0.923104906,0.697733864,1.218689865,0.732054487,DB0052610016256_,0.311900332,-0.080012393,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,oxaliplatin,DB00526
,79901,DB00650,10016256,149,1982,138,1876,0.902595374,1.021963982,0.798069109,1.30931356,0.957195726,DB0065010016256_,0.043747388,0.021726248,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,leucovorin,DB00650
,79902,DB00441,10019211,58,2216,15,1879,1.3140716842289e-05,3.277678225,1.826292629,6.248083664,0.000138051,DB0044110019211_,8.88788697,1.187135314,female,10019211,Headache,10029205,Nervous system disorders,Nerv,gemcitabine,DB00441
,79904,DB00544,10019211,49,2386,28,2625,0.00565225,1.925032102,1.181850849,3.191999898,0.022573789,DB0054410019211_,3.790965822,0.654942644,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,fluorouracil,DB00544
,79905,DB00650,10019211,62,2069,28,1986,0.000864895,2.125079556,1.333154787,3.464565756,0.004888455,DB0065010019211_,5.32087889,0.75380924,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,leucovorin,DB00650
,79906,DB00762,10019211,34,1129,33,1336,0.457087449,1.21910705,0.727454089,2.045132087,0.624391623,DB0076210019211_,0.470977507,0.198118665,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,irinotecan,DB00762
,79915,DB00813,10027175,75,10497,39,10129,0.001812771,1.855595123,1.242694297,2.809560958,0.008974232,DB0081310027175_,4.713397892,0.618205466,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,79918,DB01234,10027175,218,31407,158,32730,0.000516185,1.43785162,1.165514345,1.777071156,0.003168966,DB0123410027175_,5.754349913,0.363150069,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,79919,DB00377,10033371,108,1011,60,663,0.36210173,1.180296518,0.839314741,1.672270975,0.531767688,DB0037710033371_,0.631548561,0.165765693,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,palonosetron,DB00377
,79920,DB00526,10033371,37,1561,39,1855,0.642304958,1.127360196,0.695398781,1.824714444,0.778825317,DB0052610033371_,0.249968498,0.11987879,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,oxaliplatin,DB00526
,79942,DB00377,10047895,66,1053,46,677,0.690573633,0.922499163,0.615327676,1.392777291,0.813340559,DB0037710047895_,0.206605365,-0.08066881,NA,10047895,Weight decreased,10022891,Investigations,Inv,palonosetron,DB00377
,79943,DB00526,10047895,25,1573,51,1843,0.026519188,0.574425801,0.33936916,0.949410905,0.076899648,DB0052610047895_,2.565253981,-0.554384343,NA,10047895,Weight decreased,10022891,Investigations,Inv,oxaliplatin,DB00526
,79944,DB00544,10047895,38,2397,72,2581,0.005005959,0.568355212,0.371643079,0.857096902,0.020486009,DB0054410047895_,3.888013125,-0.565008683,NA,10047895,Weight decreased,10022891,Investigations,Inv,fluorouracil,DB00544
,79945,DB00650,10047895,28,2103,56,1958,0.000866443,0.465605962,0.283529563,0.748977213,0.004895624,DB0065010047895_,5.319413608,-0.764415578,NA,10047895,Weight decreased,10022891,Investigations,Inv,leucovorin,DB00650
,79946,DB00762,10047895,17,1146,41,1328,0.010997423,0.480627383,0.254539443,0.870387436,0.038402078,DB0076210047895_,3.2596437,-0.732662981,NA,10047895,Weight decreased,10022891,Investigations,Inv,irinotecan,DB00762
,79947,DB00889,10047895,53,727,33,484,0.820253941,1.069192407,0.668322117,1.732010244,0.904288487,DB0088910047895_,0.100606847,0.066903604,NA,10047895,Weight decreased,10022891,Investigations,Inv,granisetron,DB00889
,79948,DB01075,10047895,286,19662,156,10941,0.880833943,1.020165749,0.835211417,1.249825744,0.950123172,DB0107510047895_,0.051163648,0.019965113,NA,10047895,Weight decreased,10022891,Investigations,Inv,diphenhydramine,DB01075
,79971,DB00722,10061422,35,25368,50,25982,0.15775422,0.716949887,0.451572349,1.126968925,0.294469317,DB0072210061422_,1.222580469,-0.332749334,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,79974,DB00999,10061422,35,21395,19,12220,1,1.052141748,0.585319471,1.947943223,1,DB0099910061422_,0,0.050827846,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,79978,DB00377,10061818,120,999,65,658,0.23480188,1.215857878,0.876628181,1.698166286,0.391721458,DB0037710061818_,0.937204259,0.1954499,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,palonosetron,DB00377
,79984,DB00544,10070863,43,2392,42,2611,0.661873249,1.117519447,0.710487693,1.758918022,0.793873387,DB0054410070863_,0.230831292,0.111111449,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,fluorouracil,DB00544
,79986,DB00813,10070863,814,9758,1229,8939,2.43640075014865e-26,0.606759148,0.552089805,0.666581339,4.15849309854917e-24,DB0081310070863_,53.83688946,-0.499623357,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,79988,DB01101,10070863,52,7537,23,3885,0.625101705,1.165351217,0.699471743,1.998169922,0.764732004,DB0110110070863_,0.268229828,0.153022516,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,capecitabine,DB01101
,80008,DB00182,10011224,57,5137,18,2834,0.039152288,1.746888008,1.010838508,3.160535105,0.103930306,DB0018210011224_,2.26403474,0.557835924,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amphetamine,DB00182
,80025,DB00526,10003549,58,1540,66,1828,0.854560022,1.043140475,0.715224855,1.517845899,0.929372864,DB0052610003549_,0.07324526,0.042235851,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,oxaliplatin,DB00526
,80026,DB00544,10003549,97,2338,92,2561,0.335792623,1.154878011,0.854284804,1.562166427,0.50496648,DB0054410003549_,0.683263229,0.14399472,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,fluorouracil,DB00544
,80027,DB00762,10003549,73,1090,51,1318,0.004013608,1.730376373,1.182143162,2.549232135,0.017127636,DB0076210003549_,4.067061963,0.548338941,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,irinotecan,DB00762
,80049,DB01217,10019211,100,2654,13,255,0.310428908,0.739172925,0.405858278,1.457221836,0.477865171,DB0121710019211_,0.738426655,-0.302223386,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,anastrozole,DB01217
,80050,DB00072,10025482,71,3652,7,328,0.83414823,0.911013754,0.415246762,2.367121381,0.913889762,DB0007210025482_,0.090045326,-0.093197284,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,trastuzumab,DB00072
,80051,DB00112,10025482,131,5802,68,4023,0.058141502,1.33574091,0.986177577,1.822979841,0.139942482,DB0011210025482_,1.966523781,0.289486126,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,80054,DB01217,10025482,85,2669,8,260,1,1.035021679,0.494678219,2.502684411,1,DB0121710025482_,0,0.034422372,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,anastrozole,DB01217
,80057,DB00531,10047513,30,7222,22,6494,0.489833188,1.226158219,0.683238237,2.2333252,0.6531689,DB0053110047513_,0.425919531,0.203885882,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,cyclophosphamide,DB00531
,80118,DB00316,10054107,74,65400,17,36936,0.000413793,2.45839071,1.436472228,4.444513144,0.002634503,DB0031610054107_,5.93906085,0.899506953,NA,10054107,Nodule,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,80120,DB00635,10054107,73,32980,24,23770,0.000603368,2.192204517,1.365333452,3.637850579,0.003615121,DB0063510054107_,5.622630022,0.784907666,NA,10054107,Nodule,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,80126,DB00316,10007586,38,65436,18,36935,0.580550965,1.191574537,0.663472079,2.218413332,0.728999503,DB0031610007586_,0.316082228,0.175275573,NA,10007586,Cardiac murmur,10022891,Investigations,Inv,acetaminophen,DB00316
,80132,DB00073,10033661,106,7300,137,6270,0.001798116,0.664580214,0.509609602,0.864678905,0.008910914,DB0007310033661_,4.720478495,-0.408599695,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,rituximab,DB00073
,80133,DB01075,10042128,145,19803,48,11049,0.0014903,1.685434295,1.207275231,2.389391344,0.007649389,DB0107510042128_,4.873129466,0.522023272,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,80135,DB09153,10042128,32,7767,21,5678,0.781117625,1.113991935,0.622095586,2.034960294,0.880828655,DB0915310042128_,0.126892162,0.107949902,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,80140,DB00993,10003988,39,3210,15,1604,0.468320147,1.299164396,0.697708157,2.544897865,0.634820023,DB0099310003988_,0.454413749,0.261721285,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,azathioprine,DB00993
,80141,DB00341,10013911,57,11348,19,5049,0.31952903,1.334699888,0.781272426,2.378743826,0.487750548,DB0034110013911_,0.717951176,0.288706464,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,80145,DB00338,10014011,93,33581,42,22230,0.042648291,1.465805697,1.007363727,2.164509791,0.111018601,DB0033810014011_,2.198057512,0.382405055,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,80146,DB00341,10014011,65,11340,31,5037,0.740172019,0.931350768,0.597489626,1.480336681,0.850723836,DB0034110014011_,0.16166772,-0.071119308,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,cetirizine,DB00341
,80150,DB00541,10020772,39,3095,80,4217,0.039361594,0.664264565,0.43963559,0.988888717,0.104369969,DB0054110020772_,2.259813299,-0.409074768,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,vincristine,DB00541
,80152,DB00993,10020772,42,3207,16,1603,0.402212336,1.312057014,0.719701076,2.507820164,0.572022947,DB0099310020772_,0.558576171,0.271596145,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,azathioprine,DB00993
,80156,DB00993,10028813,180,3069,49,1570,7.12041760897773e-05,1.87900788,1.354553577,2.648148334,0.000595388,DB0099310028813_,7.426297483,0.630743914,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,azathioprine,DB00993
,80159,DB00860,10037844,59,1824,33,1463,0.110592629,1.433876222,0.915463098,2.280179383,0.226952981,DB0086010037844_,1.483012414,0.360381422,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,prednisolone,DB00860
,80160,DB00993,10037844,84,3165,33,1586,0.274702894,1.275524309,0.839075056,1.979442565,0.437941809,DB0099310037844_,0.825669233,0.243357317,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,azathioprine,DB00993
,80172,DB00341,10043554,37,11368,37,5031,0.000568644,0.44257614,0.272547238,0.718700384,0.003435256,DB0034110043554_,5.673663695,-0.815142761,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,cetirizine,DB00341
,80173,DB00541,10043554,132,3002,199,4098,0.393761311,0.905472313,0.71734024,1.140039212,0.563741717,DB0054110043554_,0.57315908,-0.099298579,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,vincristine,DB00541
,80180,DB00338,10052251,46,33628,31,22241,1,0.981401361,0.608889965,1.601566797,1,DB0033810052251_,0,-0.018773768,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,80186,DB00338,10061224,104,33570,42,22230,0.006585406,1.639713377,1.135079026,2.406818195,0.025508015,DB0033810061224_,3.668762546,0.494521457,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,80204,DB01101,10003988,98,7491,28,3880,0.004460512,1.812757414,1.178230991,2.871834428,0.018645764,DB0110110003988_,3.982136301,0.594849119,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,capecitabine,DB01101
,80213,DB00853,10010305,18,1803,45,2221,0.010403608,0.492821889,0.267514414,0.872050613,0.036732767,DB0085310010305_,3.304086081,-0.707607449,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,temozolomide,DB00853
,80218,DB00853,10053762,185,1636,201,2065,0.162280393,1.161703498,0.936116328,1.441014641,0.300425589,DB0085310053762_,1.202555179,0.149887461,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,temozolomide,DB00853
,80220,DB00264,10000381,30,29577,25,24867,1,1.00890579,0.57343398,1.789503142,1,DB0026410000381_,0,0.008866368,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,80221,DB00381,10000381,45,29315,34,22853,0.91022366,1.031782696,0.646127931,1.661644512,0.95957874,DB0038110000381_,0.041260903,0.031288079,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,80224,DB00264,10022687,52,29555,39,24853,0.600559823,1.121183726,0.725814358,1.744843487,0.744911076,DB0026410022687_,0.294490429,0.114385025,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,80225,DB00381,10022687,68,29292,42,22845,0.249317691,1.262698104,0.846764171,1.902529971,0.408739195,DB0038110022687_,0.894677992,0.233250784,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,80228,DB01115,10038695,43,3557,23,2245,0.61149035,1.179903518,0.693274368,2.057094282,0.753518596,DB0111510038695_,0.283001581,0.165432671,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nifedipine,DB01115
,80233,DB00829,10006784,60,7992,17,4437,0.0120599,1.959364202,1.12654423,3.586544327,0.041304904,DB0082910006784_,3.18677405,0.672620034,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,80250,DB00451,10015929,67,47204,12,15407,0.050637349,1.822256379,0.97723975,3.702693488,0.126172577,DB0045110015929_,2.070104652,0.600075502,NA,10015929,Eye infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,80262,DB00181,10028245,208,9648,75,5796,0.000114788,1.666017964,1.270820791,2.203906136,0.00089744,DB0018110028245_,7.015963928,0.510436327,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,80265,DB00829,10028245,57,7995,11,4443,0.000526422,2.87944578,1.492652424,6.096812513,0.003220529,DB0082910028245_,5.738209572,1.057597838,female,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,80277,DB00829,10028372,97,7955,37,4417,0.056614638,1.4556095,0.985261995,2.19140885,0.137153525,DB0082910028372_,1.986654357,0.375424713,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,diazepam,DB00829
,80279,DB00060,10030942,69,9439,11,2454,0.164056437,1.630736418,0.855456922,3.423174724,0.302814094,DB0006010030942_,1.194636214,0.489031703,NA,10030942,Optic neuritis,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,80288,DB00540,10033425,68,2415,17,1074,0.032133773,1.77862826,1.027647962,3.245120935,0.089393684,DB0054010033425_,2.414705253,0.575842427,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,nortriptyline,DB00540
,80291,DB00829,10040047,42,8010,54,4400,3.86996268964242e-05,0.427270546,0.27802056,0.652712017,0.000354803,DB0082910040047_,7.943948352,-0.850337869,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,diazepam,DB00829
,80292,DB01062,10040047,74,4412,30,1715,0.826411483,0.958828865,0.616953689,1.524209481,0.908385641,DB0106210040047_,0.096086276,-0.042042671,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,oxybutynin,DB01062
,80303,DB00181,10043607,48,9808,30,5841,0.815803013,0.952870435,0.590811365,1.559344844,0.901247741,DB0018110043607_,0.103975097,-0.04827634,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,baclofen,DB00181
,80305,DB00829,10043607,47,8005,26,4428,1,0.999938965,0.605742482,1.684405042,1,DB0082910043607_,0,-6.10E-05,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,diazepam,DB00829
,80317,DB00448,10047571,47,5098,24,3100,0.539972006,1.190758917,0.711970957,2.040457358,0.695589903,DB0044810047571_,0.362995013,0.174590849,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,lansoprazole,DB00448
,80320,DB01062,10047571,44,4442,8,1737,0.043552731,2.150502152,0.998720822,5.299806412,0.112736574,DB0106210047571_,2.182701389,0.765701374,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,oxybutynin,DB01062
,80324,DB00829,10048334,43,8009,14,4440,0.095692796,1.702660342,0.912486195,3.373594059,0.20432455,DB0082910048334_,1.588045619,0.532191935,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,diazepam,DB00829
,80328,DB00451,10048393,209,47062,23,15396,1.66796436389516e-08,2.972813018,1.927509339,4.795354169,3.55431238791929e-07,DB0045110048393_,14.84993403,1.089508649,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,80330,DB00669,10048393,44,6333,6,1091,0.69270136,1.263292601,0.534587524,3.636372768,0.814915421,DB0066910048393_,0.204670949,0.233721488,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,sumatriptan,DB00669
,80331,DB00829,10048393,130,7922,33,4421,2.28972661398381e-05,2.198319154,1.487495715,3.332932171,0.000224196,DB0082910048393_,8.402989094,0.787693047,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,80347,DB00060,10060795,70,9438,13,2452,0.339507107,1.3988827,0.765725917,2.761800785,0.508602776,DB0006010060795_,0.676087968,0.335673846,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,interferon beta-1a,DB00060
,80375,DB00334,10010774,46,2803,42,2770,0.747884738,1.082300228,0.694243585,1.691328268,0.85676961,DB0033410010774_,0.154586229,0.079088617,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,olanzapine,DB00334
,80376,DB00541,10010774,59,3075,65,4232,0.233620237,1.249173615,0.860213095,1.810934455,0.390307502,DB0054110010774_,0.940820384,0.222482225,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,vincristine,DB00541
,80377,DB00997,10010774,130,5201,45,3469,0.000118983,1.92671346,1.35892311,2.775665777,0.000924873,DB0099710010774_,6.985853848,0.655815681,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,doxorubicin,DB00997
,80379,DB00073,10012378,40,7366,37,6370,0.819075685,0.934927305,0.58198739,1.505379798,0.903514883,DB0007310012378_,0.101462697,-0.067286501,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,rituximab,DB00073
,80380,DB00334,10012378,51,2798,42,2770,0.40397587,1.2020935,0.780507343,1.860300018,0.573674523,DB0033410012378_,0.555693077,0.18406462,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,80381,DB00531,10012378,38,7214,27,6489,0.384578546,1.265940978,0.751943751,2.158646289,0.55464306,DB0053110012378_,0.589430507,0.235815702,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,cyclophosphamide,DB00531
,80384,DB00334,10013573,70,2779,60,2752,0.425959783,1.155301281,0.803128848,1.666230435,0.59472819,DB0033410013573_,0.519650802,0.144361159,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,olanzapine,DB00334
,80389,DB01075,10013786,90,19858,45,11052,0.590156824,1.113113125,0.769294634,1.630737918,0.73676613,DB0107510013786_,0.305484764,0.107160707,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,80390,DB00334,10016256,120,2729,81,2731,0.007742979,1.482456546,1.103204369,2.00047474,0.029027414,DB0033410016256_,3.539514579,0.39370054,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,olanzapine,DB00334
,80392,DB01075,10021789,204,19744,80,11017,0.007406869,1.422864871,1.092260574,1.868528628,0.028010869,DB0107510021789_,3.575162667,0.352672354,NA,10021789,Infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,80401,DB00334,10028813,147,2702,76,2736,2.05211975778972e-06,1.958309459,1.466716691,2.632353326,2.71055114741221e-05,DB0033410028813_,10.51577348,0.67208158,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,olanzapine,DB00334
,80411,DB00316,10040844,182,65292,111,36842,0.542488632,0.925193373,0.726418923,1.182760001,0.697720492,DB0031610040844_,0.359936698,-0.077752512,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,80416,DB01075,10040844,72,19876,41,11056,0.921805604,0.976813813,0.656210408,1.471545655,0.965459737,DB0107510040844_,0.035150879,-0.023459215,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,80419,DB00316,10042682,275,65199,74,36879,2.36040037641934e-09,2.102014907,1.620200627,2.756294634,6.07670165467016e-08,DB0031610042682_,16.61621869,0.742896364,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,80421,DB00531,10042682,40,7212,14,6502,0.001534174,2.575567442,1.370373933,5.129940781,0.007837854,DB0053110042682_,4.848790211,0.946069876,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,80425,DB00531,10043607,19,7233,31,6485,0.046166239,0.54954892,0.293031106,1.005143657,0.117824993,DB0053110043607_,2.138554865,-0.598657483,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,cyclophosphamide,DB00531
,80428,DB01075,10043607,121,19827,68,11029,0.939461539,0.9898161,0.728737375,1.353864339,0.978949994,DB0107510043607_,0.021274716,-0.01023611,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,diphenhydramine,DB01075
,80435,DB00531,10048959,51,7201,24,6492,0.007600013,1.915682156,1.156175098,3.258131668,0.028587054,DB0053110048959_,3.554801337,0.650073776,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,80439,DB00541,10051055,19,3115,33,4264,0.481731549,0.788156872,0.422586778,1.430370328,0.646283719,DB0054110051055_,0.436516679,-0.238058133,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,vincristine,DB00541
,80441,DB00544,10051398,34,2401,34,2619,0.807141589,1.090769403,0.655543508,1.81504405,0.895803955,DB0054410051398_,0.11003369,0.086883322,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fluorouracil,DB00544
,80442,DB00650,10051398,20,2111,34,1980,0.039303652,0.551814221,0.299895079,0.990321835,0.104253141,DB0065010051398_,2.260933287,-0.594543846,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,leucovorin,DB00650
,80482,DB00927,10008531,87,7410,67,4949,0.408290075,0.86726187,0.622036302,1.213658711,0.577693824,DB0092710008531_,0.548711266,-0.142414306,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,80484,DB00165,10011906,70,2075,61,1305,0.068399502,0.721792851,0.500945551,1.042322763,0.158391019,DB0016510011906_,1.842688498,-0.326017092,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pyridoxine,DB00165
,80486,DB01432,10011906,40,1251,26,644,0.358537446,0.792097942,0.466849465,1.365010335,0.528245104,DB0143210011906_,0.638194891,-0.23307023,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cholestyramine,DB01432
,80502,DB00927,10037660,215,7282,154,4862,0.517973534,0.932147677,0.75188422,1.157765223,0.677427323,DB0092710037660_,0.389453004,-0.070264025,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,80504,DB00165,10047942,58,2087,27,1339,0.17860333,1.37811036,0.853863486,2.275514343,0.322142903,DB0016510047942_,1.132760034,0.320713256,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,pyridoxine,DB00165
,80506,DB01060,10047942,85,8502,69,5012,0.05365735,0.726244334,0.521320932,1.014697174,0.131866995,DB0106010047942_,2.025961475,-0.319868772,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,amoxicillin,DB01060
,80507,DB01075,10047942,162,19786,104,10993,0.27467308,0.865455648,0.671604396,1.119352876,0.437920838,DB0107510047942_,0.82571712,-0.14449915,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,diphenhydramine,DB01075
,80545,DB00112,10008531,41,5892,34,4057,0.479462905,0.830343876,0.513136877,1.351554739,0.644490141,DB0011210008531_,0.439295754,-0.185915356,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,80547,DB00526,10008531,30,1568,47,1847,0.24831933,0.751934239,0.456777453,1.2206852,0.407674563,DB0052610008531_,0.897286064,-0.285106407,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,oxaliplatin,DB00526
,80559,DB01101,10043224,51,7538,14,3894,0.035360794,1.881744315,1.024359471,3.686060137,0.09618736,DB0110110043224_,2.341457319,0.632199174,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,80568,DB00112,10035528,175,5758,60,4031,8.07390064844165e-07,2.041722426,1.510137857,2.793399151,1.18664356591748e-05,DB0011210035528_,11.34179668,0.713793778,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,bevacizumab,DB00112
,80571,DB00567,10003239,109,4410,35,2046,0.069287321,1.444784053,0.975177329,2.187479866,0.160050727,DB0056710003239_,1.832264471,0.367959866,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cephalexin,DB00567
,80590,DB00112,10029354,113,5820,62,4029,0.162410595,1.261685184,0.914989382,1.753598068,0.300570513,DB0011210029354_,1.2020729,0.232448275,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,bevacizumab,DB00112
,80598,DB00448,10025482,146,4999,35,3089,9.3047291053713e-08,2.57736064,1.766645237,3.852955729,1.69490509033045e-06,DB0044810025482_,13.28788381,0.946765867,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,80600,DB00448,10050584,52,5093,22,3102,0.184874715,1.439562373,0.857129008,2.494219629,0.329989941,DB0044810050584_,1.108693107,0.36433916,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,lansoprazole,DB00448
,80601,DB00959,10050584,71,8007,18,4984,0.000396894,2.455086376,1.445568155,4.382596644,0.002545721,DB0095910050584_,5.973341531,0.898161944,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,methylprednisolone,DB00959
,80604,DB00889,10010774,60,720,33,484,0.38207762,1.222036213,0.772867199,1.96105003,0.552169216,DB0088910010774_,0.593900729,0.200518494,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,granisetron,DB00889
,80605,DB00950,10010774,103,4615,27,2029,0.015902663,1.677081191,1.084874214,2.675009798,0.051605124,DB0095010010774_,2.964134303,0.517054896,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,fexofenadine,DB00950
,80607,DB00316,10011878,87,65387,37,36916,0.160829499,1.32751542,0.893657764,2.007194504,0.298629795,DB0031610011878_,1.208550616,0.28330909,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,acetaminophen,DB00316
,80611,DB01234,10011878,42,31583,53,32835,0.357358714,0.82387047,0.535975724,1.259277065,0.527069763,DB0123410011878_,0.640422361,-0.193741958,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,dexamethasone,DB01234
,80612,DB00950,10012735,289,4429,100,1956,0.040901338,1.276232801,1.00659937,1.628848446,0.107450069,DB0095010012735_,2.230729016,0.243912614,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fexofenadine,DB00950
,80613,DB00950,10016256,349,4369,139,1917,0.384945297,1.101660753,0.895583744,1.360856672,0.555050173,DB0095010016256_,0.588696768,0.096818817,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,80614,DB00950,10016825,46,4672,13,2043,0.200249917,1.547233019,0.819730322,3.128727323,0.349286245,DB0095010016825_,1.051863508,0.436468187,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,fexofenadine,DB00950
,80619,DB00950,10020642,38,4680,15,2041,0.880907284,1.104796431,0.592144005,2.16700516,0.950123172,DB0095010020642_,0.051163648,0.099661093,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,fexofenadine,DB00950
,80627,DB00950,10028735,51,4667,15,2041,0.225322239,1.486850043,0.820631104,2.854075067,0.380165291,DB0095010028735_,0.967149146,0.396659817,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fexofenadine,DB00950
,80636,DB01234,10043882,65,31560,57,32831,0.365492568,1.18627085,0.818069437,1.724371598,0.535124288,DB0123410043882_,0.625256245,0.170814647,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,dexamethasone,DB01234
,80639,DB00316,10049088,72,65402,11,36942,5.25311084172918e-06,3.697125236,1.947676664,7.733835823,6.17798740379649e-05,DB0031610049088_,9.691932909,1.307555555,female,10049088,Osteopenia,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,80644,DB00316,10052251,69,65405,40,36913,0.92061317,0.973530895,0.650041838,1.475696474,0.964812755,DB0031610052251_,0.035821232,-0.026825719,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,80648,DB01234,10052251,40,31585,55,32833,0.18331335,0.756014322,0.489993666,1.15732445,0.328016026,DB0123410052251_,1.114692811,-0.279694958,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,80653,DB01609,10018884,31,1553,43,1300,0.033883807,0.603595706,0.365407823,0.986765824,0.093148132,DB0160910018884_,2.373564234,-0.504850666,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,deferasirox,DB01609
,80654,DB01609,10037660,33,1551,32,1311,0.615888424,0.87171787,0.51643302,1.473035862,0.757185557,DB0160910037660_,0.278146934,-0.137289451,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,deferasirox,DB01609
,80668,DB00958,10011224,97,4497,54,2531,1,1.010989525,0.714737282,1.442870738,1,DB0095810011224_,0,0.010929579,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carboplatin,DB00958
,80669,DB00112,10013950,47,5886,30,4061,0.816233963,1.080916491,0.668194411,1.773342649,0.901529928,DB0011210013950_,0.103662039,0.077809284,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,80671,DB00958,10013950,58,4536,39,2546,0.395378404,0.834765739,0.545083561,1.290623797,0.565042842,DB0095810013950_,0.570853723,-0.180604145,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,carboplatin,DB00958
,80672,DB01229,10013950,62,5679,54,2655,0.001239458,0.53679048,0.365529755,0.790469517,0.006566815,DB0122910013950_,5.025726416,-0.622147428,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,paclitaxel,DB01229
,80676,DB00112,10025197,37,5896,15,4076,0.089593875,1.705157455,0.912093731,3.34872715,0.194561714,DB0011210025197_,1.637005868,0.533657455,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,bevacizumab,DB00112
,80684,DB01101,10010305,57,7532,15,3893,0.017541129,1.96397111,1.095399488,3.740059283,0.055765431,DB0110110010305_,2.886601112,0.6749685,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,capecitabine,DB01101
,80690,DB00158,10013971,59,16756,33,8071,0.504321963,0.861196804,0.552714411,1.362702988,0.665390872,DB0015810013971_,0.407380634,-0.149432225,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,80715,DB00635,10029410,87,32966,63,23731,1,0.994095902,0.710261512,1.398118226,1,DB0063510029410_,0,-0.005921596,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,80729,DB00531,10035664,226,7026,245,6271,0.038878988,0.823338351,0.681857761,0.993826573,0.103387547,DB0053110035664_,2.269270758,-0.194388043,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,80731,DB00773,10035664,62,2261,82,2745,0.671257981,0.917939448,0.645986599,1.298902591,0.800527031,DB0077310035664_,0.22248498,-0.085623851,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,etoposide,DB00773
,80734,DB00531,10047895,90,7162,98,6418,0.186471948,0.822979666,0.609927079,1.10932739,0.332039157,DB0053110047895_,1.102502373,-0.194823786,NA,10047895,Weight decreased,10022891,Investigations,Inv,cyclophosphamide,DB00531
,80735,DB00541,10047895,35,3099,70,4227,0.072984784,0.682028833,0.439817881,1.040548864,0.166506535,DB0054110047895_,1.792720723,-0.382683344,NA,10047895,Weight decreased,10022891,Investigations,Inv,vincristine,DB00541
,80736,DB00773,10047895,22,2301,30,2797,0.77977419,0.891448911,0.488503644,1.602894724,0.880132524,DB0077310047895_,0.127682787,-0.11490715,NA,10047895,Weight decreased,10022891,Investigations,Inv,etoposide,DB00773
,80747,DB00158,10015150,186,16629,44,8060,7.20644230786878e-06,2.04888799,1.466446478,2.917930523,8.14715423924004e-05,DB0015810015150_,9.415256772,0.717297202,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,80748,DB00331,10015150,177,24769,95,20657,0.000482876,1.553829215,1.203403441,2.016789976,0.003003764,DB0033110015150_,5.807889035,0.440722345,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,80749,DB01222,10015150,74,9200,37,5368,0.489872687,1.166975488,0.775032428,1.784257626,0.653205001,DB0122210015150_,0.425864262,0.154415348,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,budesonide,DB01222
,80753,DB00158,10020919,41,16774,28,8076,0.158084171,0.704985954,0.425224411,1.184678739,0.294896734,DB0015810020919_,1.22113004,-0.3495774,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,folic acid,DB00158
,80755,DB00695,10020919,381,27668,216,20312,0.002659463,1.294921895,1.091838307,1.53886844,0.012255256,DB0069510020919_,4.401800353,0.258450381,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,80757,DB01015,10020919,27,9860,42,9339,0.052847227,0.608908912,0.360702914,1.01189162,0.130415653,DB0101510020919_,2.037028601,-0.496086592,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,sulfamethoxazole,DB01015
,80758,DB01222,10020919,59,9215,32,5373,0.827576969,1.075039998,0.686712303,1.711008802,0.909305492,DB0122210020919_,0.095074166,0.072357869,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,budesonide,DB01222
,80784,DB00158,10029354,88,16727,89,8015,1.03305650272203e-06,0.473786277,0.348366718,0.644264819,1.47135682330255e-05,DB0015810029354_,11.12674048,-0.746998951,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,folic acid,DB00158
,80786,DB00829,10029354,20,8032,33,4421,0.000128121,0.333620736,0.181179914,0.599698961,0.000984982,DB0082910029354_,6.922887039,-1.097750453,male,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,diazepam,DB00829
,80790,DB00829,10030124,56,7996,24,4430,0.348826823,1.292724355,0.786927546,2.184076771,0.518339818,DB0082910030124_,0.657124233,0.256751895,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,80793,DB00158,10033661,80,16735,75,8029,4.53011880272464e-05,0.511754194,0.368347863,0.711723988,0.000406258,DB0015810033661_,7.808522528,-0.66991086,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,folic acid,DB00158
,80796,DB01222,10033661,20,9254,42,5363,9.37008498062483e-07,0.275993295,0.153356565,0.481268411,1.35251336472116e-05,DB0122210033661_,11.21096085,-1.287378706,male,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,budesonide,DB01222
,80811,DB00073,10074170,29,7377,41,6366,0.041713143,0.610409708,0.365398122,1.007628421,0.109151813,DB0007310074170_,2.215015587,-0.493624894,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,rituximab,DB00073
,80816,DB00695,10074170,55,27994,21,20507,0.010261211,1.918547229,1.141222028,3.341048422,0.036309275,DB0069510074170_,3.315682061,0.651568248,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,80818,DB01015,10074170,28,9859,30,9351,0.693970356,0.885248104,0.509193208,1.534603894,0.815769362,DB0101510074170_,0.203623609,-0.12188733,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,80819,DB01234,10074170,68,31557,62,32826,0.482842042,1.140875515,0.796412628,1.636975944,0.647067599,DB0123410074170_,0.435304509,0.131795963,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,80832,DB01409,10000059,53,5978,32,3934,0.739444288,1.089951166,0.688501358,1.750354464,0.85016024,DB0140910000059_,0.16233043,0.086132894,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,tiotropium,DB01409
,80835,DB00688,10021143,65,6425,63,5315,0.373790338,0.853512165,0.592965808,1.229215286,0.543586774,DB0068810021143_,0.609565927,-0.158395484,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolate mofetil,DB00688
,80844,DB00999,10011878,42,21388,18,12221,0.348381674,1.333244409,0.750623841,2.461753219,0.517963107,DB0099910011878_,0.657851261,0.287615377,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,hydrochlorothiazide,DB00999
,80867,DB00437,10013538,34,6887,27,11519,0.004943122,2.106148157,1.232262392,3.632888143,0.020288876,DB0043710013538_,3.897682529,0.744860761,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,allopurinol,DB00437
,80868,DB00641,10013538,55,14069,28,12447,0.020163169,1.737784345,1.082665581,2.847161929,0.062168786,DB0064110013538_,2.777902238,0.552610937,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,simvastatin,DB00641
,80869,DB00641,10018627,20,14104,40,12435,0.002626748,0.440843318,0.243997772,0.772601158,0.012133218,DB0064110018627_,4.411808298,-0.819065754,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,simvastatin,DB00641
,80881,DB00437,10036018,16,6905,38,11508,0.261808346,0.701747002,0.365014831,1.290009148,0.423485069,DB0043710036018_,0.859237021,-0.354182336,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,allopurinol,DB00437
,80882,DB00641,10036018,47,14077,41,12434,1,1.012546376,0.651331996,1.579775816,1,DB0064110036018_,0,0.012468322,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,simvastatin,DB00641
,80890,DB00437,10047513,46,6875,53,11493,0.076248252,1.450837994,0.954634621,2.197874396,0.171870792,DB0043710047513_,1.761012294,0.372141317,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,allopurinol,DB00437
,80894,DB01076,10047626,33,25714,18,25565,0.048820806,1.822678418,0.996609204,3.439018663,0.122799511,DB0107610047626_,2.097202247,0.600307078,NA,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,80901,DB00641,10057668,42,14082,46,12429,0.336350136,0.805876088,0.517145023,1.252767398,0.505428957,DB0064110057668_,0.682347791,-0.215825286,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,80911,DB00181,10036018,54,9802,14,5857,0.003673007,2.304651379,1.261145816,4.496855236,0.015931517,DB0018110036018_,4.139455933,0.834929419,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,baclofen,DB00181
,80913,DB00181,10046543,61,9795,41,5830,0.539783547,0.885553908,0.585600016,1.351346466,0.695517563,DB0018110046543_,0.363099015,-0.121541945,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,baclofen,DB00181
,80916,DB00181,10060800,49,9807,15,5856,0.026840607,1.950529344,1.074610462,3.748268273,0.077651792,DB0018110060800_,2.555520652,0.668100794,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,baclofen,DB00181
,80923,DB00213,10025082,52,18843,28,13393,0.257108367,1.319985694,0.817931499,2.171861242,0.417978997,DB0021310025082_,0.872324093,0.277620898,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,80929,DB00213,10028372,152,18743,108,13313,1,0.999665677,0.775187017,1.292788912,1,DB0021310028372_,0,-0.000334379,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,80930,DB00437,10028372,59,6862,115,11431,0.345905909,0.854630185,0.612639861,1.18157562,0.515339615,DB0043710028372_,0.662929149,-0.157086436,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,allopurinol,DB00437
,80931,DB00836,10028372,49,5486,39,4036,0.745669076,0.924337653,0.593325782,1.448695265,0.85479359,DB0083610028372_,0.156895254,-0.078677849,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,loperamide,DB00836
,80934,DB00285,10009033,45,10906,18,3700,0.562239565,0.848193957,0.480560829,1.558941316,0.714487864,DB0028510009033_,0.336189267,-0.164645946,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,venlafaxine,DB00285
,80935,DB00285,10016173,321,10630,123,3595,0.245034867,0.882624406,0.712210284,1.099437956,0.403795585,DB0028510016173_,0.906846507,-0.124855531,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,80940,DB00285,10030124,58,10893,20,3698,1,0.984504419,0.582438712,1.73053314,1,DB0028510030124_,0,-0.015616893,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,80944,DB00060,10013700,58,9450,13,2452,0.768435913,1.157624832,0.625650712,2.306896308,0.873007498,DB0006010013700_,0.135811134,0.146370347,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,interferon beta-1a,DB00060
,80958,DB00461,10028813,63,1027,13,312,0.261783418,1.471840536,0.788717788,2.955495004,0.423469221,DB0046110028813_,0.859274446,0.386513683,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,nabumetone,DB00461
,80962,DB01373,10042128,176,22544,20,7361,6.32475821483139e-07,2.873398672,1.803230914,4.823526173,9.54341387352716e-06,DB0137310042128_,11.55965929,1.055495535,female,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,80968,DB01373,10050296,60,22660,8,7373,0.015467187,2.440375237,1.161510727,5.913054189,0.050487019,DB0137310050296_,2.98603903,0.892151813,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,80971,DB00787,10007559,85,16915,120,17128,0.020636781,0.717262699,0.536306844,0.955755571,0.063354098,DB0078710007559_,2.75901568,-0.332313119,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,acyclovir,DB00787
,80981,DB00390,10043554,27,4118,34,3267,0.091711941,0.630059426,0.364812368,1.078278577,0.19801613,DB0039010043554_,1.619406788,-0.461941137,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,digoxin,DB00390
,80992,DB00924,10047899,212,9950,43,4208,4.06996729709585e-06,2.084977148,1.492981544,2.971341647,4.93104818640997e-05,DB0092410047899_,9.917373886,0.734757895,NA,10047899,Weight increased,10022891,Investigations,Inv,cyclobenzaprine,DB00924
,80994,DB00108,10039203,67,10127,34,3261,0.035948022,0.634574107,0.413146545,0.990984414,0.097423862,DB0010810039203_,2.328684106,-0.454801202,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,natalizumab,DB00108
,81002,DB00112,10000060,69,5864,27,4064,0.011958548,1.77100852,1.117736876,2.880556753,0.041037983,DB0011210000060_,3.193257239,0.57154917,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,81004,DB01101,10000060,54,7535,30,3878,0.729972544,0.926404488,0.581227183,1.502226822,0.84284454,DB0110110000060_,0.170972751,-0.076444328,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,81022,DB00736,10027599,95,10496,16,5537,2.81645063653337e-06,3.132055267,1.830425967,5.707312783,3.58500750514672e-05,DB0073610027599_,10.2361649,1.141689424,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,81023,DB00959,10027599,69,8009,11,4991,2.27858935353314e-06,3.908674134,2.051875967,8.199547288,2.9708691050406e-05,DB0095910027599_,10.42407093,1.36319822,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,81024,DB00273,10042209,59,8422,8,2185,0.09423463,1.913232593,0.90852147,4.64394826,0.202134589,DB0027310042209_,1.598821519,0.648794268,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,81034,DB00959,10051055,45,8033,30,4972,0.811828912,0.928426357,0.571325815,1.528491301,0.898935166,DB0095910051055_,0.106544366,-0.074264215,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,methylprednisolone,DB00959
,81036,DB00736,10053762,302,10289,161,5392,0.881650084,0.98300233,0.806804376,1.201221767,0.950483399,DB0073610053762_,0.050784582,-0.017143788,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,esomeprazole,DB00736
,81037,DB06700,10053762,78,2147,28,590,0.231410824,0.765597136,0.486071938,1.237075766,0.387636735,DB0670010053762_,0.947686627,-0.267099179,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,desvenlafaxine,DB06700
,81039,DB00437,10013781,34,6887,47,11499,0.421587572,1.207820105,0.752526954,1.920441201,0.590663043,DB0043710013781_,0.526509572,0.188817169,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,81040,DB00761,10013781,72,15235,31,8594,0.218802635,1.310149632,0.848016073,2.067500687,0.372043035,DB0076110013781_,0.988745746,0.270141353,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,81041,DB00904,10013781,127,22942,37,14419,1.71546744499426e-05,2.157230681,1.484410422,3.203612428,0.0001744,DB0090410013781_,8.654160337,0.768825307,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,81042,DB01234,10013781,124,31501,67,32821,1.17505735521113e-05,1.928266081,1.420649248,2.637239884,0.000125046,DB0123410013781_,8.986828222,0.656621195,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,81045,DB00761,10016100,31,15276,25,8600,0.209424301,0.698126796,0.39864493,1.234068633,0.360492322,DB0076110016100_,1.020284621,-0.359354537,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,81047,DB01234,10016100,34,31591,16,32872,0.010129616,2.211151504,1.187356734,4.290869875,0.035936962,DB0123410016100_,3.325988938,0.793513422,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,81049,DB00761,10018838,75,15232,38,8587,0.624614546,1.112668799,0.742780538,1.691559793,0.764374195,DB0076110018838_,0.268697825,0.106761453,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,81050,DB00904,10018838,86,22983,47,14409,0.476211325,1.147196954,0.794339614,1.674759819,0.641621308,DB0090410018838_,0.443757012,0.137321536,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,ondansetron,DB00904
,81051,DB01075,10018838,33,19915,25,11072,0.272620109,0.733902548,0.423068188,1.287996756,0.435544773,DB0107510018838_,0.831157679,-0.309379028,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,diphenhydramine,DB01075
,81052,DB09153,10018838,24,7775,36,5663,0.005827463,0.485593608,0.276812854,0.837743775,0.023129464,DB0915310018838_,3.76664796,-0.722383202,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,sodium chloride,DB09153
,81054,DB00316,10018910,69,65405,34,36919,0.53990347,1.145557251,0.749077634,1.782208356,0.695552748,DB0031610018910_,0.363048429,0.1358912,NA,10018910,Haemolysis,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,81062,DB00316,10025282,69,65405,13,36940,7.29470819291151e-05,2.997688879,1.642495829,5.912453072,0.000607835,DB0031610025282_,7.405607855,1.097841618,female,10025282,Lymphoedema,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,81078,DB00904,10041349,227,22842,107,14349,0.015071369,1.332681351,1.053402213,1.694816754,0.049506492,DB0090410041349_,3.005651472,0.287192966,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,81079,DB09153,10041349,65,7734,27,5672,0.014410601,1.765479134,1.109566536,2.881053379,0.047699615,DB0915310041349_,3.04283195,0.568422118,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,81080,DB00761,10047943,61,15246,18,8607,0.013524776,1.913120257,1.114818646,3.441963637,0.045283579,DB0076110047943_,3.0948108,0.648735551,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,potassium chloride,DB00761
,81081,DB01234,10047943,45,31580,42,32846,0.668151652,1.11437832,0.715180322,1.739597723,0.798398244,DB0123410047943_,0.225147754,0.108296688,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,dexamethasone,DB01234
,81085,DB00904,10051608,34,23035,19,14437,0.77816507,1.121557351,0.621554576,2.082220271,0.879072925,DB0090410051608_,0.128887421,0.114718212,NA,10051608,Platelet count increased,10022891,Investigations,Inv,ondansetron,DB00904
,81094,DB01229,10033661,68,5673,29,2680,0.742840755,1.10771073,0.705493033,1.779409409,0.852793904,DB0122910033661_,0.159237373,0.102295481,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,paclitaxel,DB01229
,81095,DB00982,10011469,40,3324,17,2084,0.217906127,1.475089229,0.814987253,2.782561374,0.371074465,DB0098210011469_,0.991352522,0.388718482,NA,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,isotretinoin,DB00982
,81121,DB11093,10013709,47,1610,13,647,0.30979586,1.45272216,0.76686596,2.947111074,0.47725848,DB1109310013709_,0.739697048,0.373439148,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,calcium citrate,DB11093
,81149,DB11093,10035664,60,1597,28,632,0.471941586,0.848098888,0.527407138,1.393317283,0.638049507,DB1109310035664_,0.449339402,-0.164758037,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,calcium citrate,DB11093
,81150,DB13961,10035664,284,9173,232,6182,0.035832842,0.825004631,0.689027527,0.988575629,0.09718979,DB1396110035664_,2.331089615,-0.192366279,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,fish oil,DB13961
,81151,DB00169,10039117,106,38585,59,18116,0.31572678,0.843540324,0.607556164,1.180861067,0.483352655,DB0016910039117_,0.727008757,-0.170147573,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,81155,DB00169,10041541,59,38632,29,18146,0.820032214,0.955626708,0.602615847,1.546703427,0.904209528,DB0016910041541_,0.100694166,-0.045387915,NA,10041541,Spinal compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,81159,DB00169,10042609,142,38549,34,18141,0.000245298,1.96540898,1.343240056,2.949326798,0.001707082,DB0016910042609_,6.372970022,0.675700356,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,cholecalciferol,DB00169
,81160,DB00404,10042609,56,19836,19,9843,0.176600996,1.462522687,0.855273704,2.608024526,0.319495986,DB0040410042609_,1.141010568,0.380162813,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,alprazolam,DB00404
,81162,DB13961,10042609,42,9415,14,6400,0.019927253,2.039206655,1.090585022,4.046375656,0.06158734,DB1396110042609_,2.787298953,0.712560838,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,fish oil,DB13961
,81176,DB00169,10049088,89,38602,14,18161,2.835515139836e-05,2.990783971,1.69172005,5.692786435,0.000270042,DB0016910049088_,8.216934083,1.095535551,female,10049088,Osteopenia,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,81225,DB00158,10024264,48,16767,24,8080,0.899990336,0.963817929,0.578383777,1.646343504,0.956571579,DB0015810024264_,0.044399659,-0.036852873,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,81226,DB00863,10024264,44,10629,35,5805,0.099596967,0.686571824,0.429926619,1.103999301,0.210170636,DB0086310024264_,1.559835527,-0.376044435,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,81243,DB00203,10048634,144,13734,40,8898,6.24536537576651e-07,2.332285062,1.631126723,3.402794538,9.43716176499125e-06,DB0020310048634_,11.57085528,0.8468485,NA,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,81244,DB00682,10048634,109,19350,21,16343,1.29021695340999e-12,4.383644077,2.728565959,7.369438224,5.72377259415723e-11,DB0068210048634_,23.58380789,1.477880359,female,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,81250,DB00203,10064355,54,13824,35,8903,1,0.99363784,0.637012266,1.568068566,1,DB0020310064355_,0,-0.006382485,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,81252,DB06403,10064355,44,21427,15,6646,0.759459255,0.909821712,0.496290382,1.761313898,0.866028352,DB0640310064355_,0.143837632,-0.09450662,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,ambrisentan,DB06403
,81254,DB00635,10007617,31,33022,51,23743,0.000283062,0.437045538,0.270235293,0.696454595,0.001926151,DB0063510007617_,6.252231684,-0.827717884,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,prednisone,DB00635
,81256,DB00635,10019663,42,33011,35,23759,0.563821094,0.863680537,0.53813319,1.393892776,0.715713867,DB0063510019663_,0.334474818,-0.146552328,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,prednisone,DB00635
,81260,DB00295,10013654,474,14189,406,9196,6.12422900042764e-05,0.756679509,0.659558959,0.868342529,0.000524606,DB0029510013654_,7.552863003,-0.278815486,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,morphine,DB00295
,81262,DB00295,10062237,33,14630,22,9580,1,0.982222907,0.555372563,1.769480059,1,DB0029510062237_,0,-0.017937003,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,morphine,DB00295
,81276,DB00531,10001551,32,7220,54,6462,0.004630124,0.53040785,0.330976738,0.83751873,0.019222291,DB0053110001551_,3.951684659,-0.63410904,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,cyclophosphamide,DB00531
,81277,DB00635,10001551,128,32925,145,23649,0.000212195,0.634077063,0.495657538,0.81032444,0.001513583,DB0063510001551_,6.493275897,-0.455584782,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,prednisone,DB00635
,81278,DB00996,10001551,97,38856,62,22363,0.510849638,0.900438201,0.64777005,1.259791541,0.671199557,DB0099610001551_,0.398688783,-0.104873744,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,gabapentin,DB00996
,81285,DB08889,10002034,70,3095,70,3815,0.230183307,1.232591018,0.869063602,1.748240384,0.386160851,DB0888910002034_,0.951501284,0.209118472,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,carfilzomib,DB08889
,81286,DB09270,10002034,44,3070,46,2322,0.133792744,0.723519337,0.465759007,1.122632179,0.261040846,DB0927010002034_,1.343078386,-0.323628006,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ubidecarenone,DB09270
,81292,DB00531,10003481,40,7212,41,6475,0.578028632,0.875920767,0.551456862,1.390309944,0.726856556,DB0053110003481_,0.319026131,-0.132479641,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,cyclophosphamide,DB00531
,81293,DB00635,10003481,120,32933,123,23671,0.006137175,0.701247881,0.540387796,0.909734818,0.024093914,DB0063510003481_,3.725796005,-0.354893844,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,prednisone,DB00635
,81294,DB00996,10003481,99,38854,65,22360,0.417450812,0.876518121,0.634314133,1.218256264,0.586524192,DB0099610003481_,0.533541364,-0.131797901,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,gabapentin,DB00996
,81323,DB00531,10005364,23,7229,32,6484,0.135946738,0.644703984,0.359846779,1.138039797,0.264008866,DB0053110005364_,1.331772592,-0.438964006,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,cyclophosphamide,DB00531
,81324,DB00635,10005364,70,32983,60,23734,0.328563566,0.839519648,0.585887051,1.206176697,0.49716731,DB0063510005364_,0.69882867,-0.174925398,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,prednisone,DB00635
,81327,DB09153,10005364,30,7769,37,5662,0.034833529,0.590950567,0.352123982,0.984340902,0.095102499,DB0915310005364_,2.352800031,-0.526022908,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,sodium chloride,DB09153
,81340,DB01234,10005396,44,31581,39,32849,0.510380667,1.173499056,0.744908029,1.854993437,0.670784562,DB0123410005396_,0.399307264,0.159989931,NA,10005396,Blood calcium increased,10022891,Investigations,Inv,dexamethasone,DB01234
,81362,DB00188,10005483,34,7852,58,8770,0.05890813,0.654760446,0.415211488,1.018096,0.141406411,DB0018810005483_,1.956117186,-0.423485841,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,bortezomib,DB00188
,81367,DB09153,10005483,33,7766,55,5644,0.000132819,0.436078318,0.27390931,0.684547313,0.001015754,DB0915310005483_,6.89212432,-0.829933424,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,sodium chloride,DB09153
,81372,DB00188,10005557,35,7851,38,8790,0.907017797,1.031220361,0.631828201,1.678630172,0.958537515,DB0018810005557_,0.042346578,0.030742917,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,bortezomib,DB00188
,81375,DB00425,10005557,54,12641,52,7432,0.011699691,0.610584055,0.408916887,0.912374264,0.040344556,DB0042510005557_,3.210298808,-0.493339313,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,zolpidem,DB00425
,81416,DB00169,10005725,44,38647,37,18138,0.011724797,0.558151258,0.352112486,0.889106248,0.040412574,DB0016910005725_,3.208614298,-0.583125281,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,81421,DB00338,10005725,48,33626,33,22239,0.90969906,0.961957365,0.604642366,1.547423328,0.959437782,DB0033810005725_,0.04140781,-0.038785148,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,omeprazole,DB00338
,81426,DB00996,10005725,40,38913,38,22387,0.033448086,0.605623185,0.378534892,0.970363082,0.092239725,DB0099610005725_,2.38336438,-0.501497294,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,gabapentin,DB00996
,81428,DB01234,10005725,17,31608,34,32854,0.025408913,0.519717861,0.272233824,0.956670711,0.07439805,DB0123410005725_,2.598325554,-0.65446919,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,dexamethasone,DB01234
,81440,DB00996,10005802,54,38899,23,22402,0.238541453,1.35211054,0.815634677,2.309128394,0.396267908,DB0099610005802_,0.925664761,0.301666734,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,gabapentin,DB00996
,81442,DB01234,10005802,28,31597,31,32857,0.896522558,0.939222578,0.542727995,1.618762646,0.956301489,DB0123410005802_,0.044682051,-0.062702791,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,81455,DB00635,10005851,44,33009,37,23757,0.500336435,0.855879965,0.53998213,1.363382165,0.661919279,DB0063510005851_,0.412611666,-0.15562514,NA,10005851,Blood urea increased,10022891,Investigations,Inv,prednisone,DB00635
,81456,DB00996,10005851,50,38903,25,22400,0.631968944,1.151604236,0.698836283,1.943205877,0.770701819,DB0099610005851_,0.260453725,0.141155958,NA,10005851,Blood urea increased,10022891,Investigations,Inv,gabapentin,DB00996
,81501,DB00338,10007636,31,33643,25,22247,0.495641035,0.819980319,0.468423042,1.448897402,0.657992606,DB0033810007636_,0.418561585,-0.19847494,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,omeprazole,DB00338
,81509,DB00169,10009887,116,38575,55,18120,0.934763047,0.990712384,0.712432149,1.392320972,0.975176325,DB0016910009887_,0.025136978,-0.009331015,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,81513,DB00425,10009887,34,12661,21,7463,0.889275421,0.954361089,0.537711506,1.731708746,0.953995558,DB0042510009887_,0.047096264,-0.046713179,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,81514,DB00531,10009887,52,7200,97,6419,1.48609356769478e-05,0.477961692,0.33389443,0.677439558,0.000153748,DB0053110009887_,8.780192993,-0.738224693,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,81517,DB09153,10009887,36,7763,28,5671,0.801192205,0.939249472,0.556581394,1.599982879,0.892454221,DB0915310009887_,0.11378006,-0.062674157,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,81619,DB00169,10029366,121,38570,54,18121,0.807774386,1.052745906,0.757427541,1.479907656,0.896255547,DB0016910029366_,0.109529698,0.051401899,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,81622,DB00338,10029366,90,33584,76,22196,0.131141921,0.782669634,0.570033932,1.077064186,0.257445416,DB0033810029366_,1.356947556,-0.245044596,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,omeprazole,DB00338
,81631,DB00531,10035528,140,7112,233,6283,3.06513230402184e-09,0.530850204,0.426149908,0.659328009,7.73214153504156e-08,DB0053110035528_,16.37529488,-0.633275399,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,cyclophosphamide,DB00531
,81633,DB08889,10035528,78,3087,114,3771,0.239704723,0.835835585,0.615943084,1.129327579,0.397516634,DB0888910035528_,0.9225185,-0.179323354,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,carfilzomib,DB08889
,81634,DB09153,10035528,42,7757,47,5652,0.052042492,0.651152197,0.418419846,1.010382374,0.128880431,DB0915310035528_,2.048870199,-0.429011875,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,sodium chloride,DB09153
,81635,DB09270,10035528,37,3077,44,2324,0.054062802,0.635187878,0.39745957,1.010054541,0.13259688,DB0927010035528_,2.020441731,-0.453834453,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,ubidecarenone,DB09270
,81644,DB00635,10036653,56,32997,35,23759,0.525825036,1.152022372,0.741762399,1.811656348,0.683783262,DB0063510036653_,0.38011428,0.141518982,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,81663,DB01234,10037016,42,31583,42,32846,0.913186818,1.040001739,0.66150771,1.635026142,0.961104948,DB0123410037016_,0.039671669,0.039222385,NA,10037016,Protein total increased,10022891,Investigations,Inv,dexamethasone,DB01234
,81672,DB08889,10038153,20,3145,35,3850,0.222221071,0.699558873,0.381839763,1.248683611,0.376334054,DB0888910038153_,0.97727809,-0.357305324,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,carfilzomib,DB08889
,81677,DB00327,10043554,54,6084,57,4205,0.032324143,0.654823404,0.441857956,0.969345718,0.089795772,DB0032710043554_,2.410217388,-0.423389693,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,hydromorphone,DB00327
,81679,DB09153,10043554,55,7744,77,5622,0.000252624,0.518594837,0.359434954,0.743962706,0.001751116,DB0915310043554_,6.347501963,-0.656632362,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,sodium chloride,DB09153
,81683,DB00338,10047942,416,33258,294,21978,0.3960339,0.935058515,0.802597778,1.090443165,0.565670483,DB0033810047942_,0.569743556,-0.067146169,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,omeprazole,DB00338
,81685,DB08889,10047942,67,3098,90,3795,0.62653117,0.911914906,0.652107246,1.269999983,0.766095495,DB0888910047942_,0.26644845,-0.092208598,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,carfilzomib,DB08889
,81686,DB09153,10047942,50,7749,43,5656,0.461454238,0.848735213,0.552384247,1.308926426,0.628726734,DB0915310047942_,0.464058562,-0.164008022,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,sodium chloride,DB09153
,81687,DB09270,10047942,71,3043,43,2325,0.252228402,1.261515251,0.848304641,1.895264977,0.412328101,DB0927010047942_,0.885935884,0.232313579,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,ubidecarenone,DB09270
,81688,DB11133,10047942,40,2391,32,1542,0.394799908,0.806200605,0.491461392,1.332153051,0.564682319,DB1113310047942_,0.571491974,-0.215422678,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,omega-3 fatty acids,DB11133
,81714,DB00635,10059570,59,32994,47,23747,0.622996768,0.903502222,0.605224184,1.355486892,0.763140556,DB0063510059570_,0.27031305,-0.10147671,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,prednisone,DB00635
,81716,DB01234,10059570,26,31599,34,32854,0.438682684,0.795081579,0.458064822,1.365059752,0.607010653,DB0123410059570_,0.499208938,-0.229310555,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,dexamethasone,DB01234
,81721,DB00012,10061818,85,1561,47,1266,0.039427986,1.466547566,1.006756263,2.158457781,0.104498575,DB0001210061818_,2.258581844,0.382911044,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,darbepoetin alfa,DB00012
,81723,DB00190,10061818,19,3278,40,4634,0.184331099,0.67152454,0.366634969,1.189400231,0.329336882,DB0019010061818_,1.110674093,-0.398204719,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,81725,DB00425,10061818,128,12567,75,7409,1,1.006182091,0.74966904,1.358553262,1,DB0042510061818_,0,0.006163061,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,81727,DB08889,10061818,51,3114,104,3781,0.002446035,0.595465671,0.415853683,0.84332225,0.011465722,DB0888910061818_,4.468393382,-0.518411539,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,81728,DB09153,10061818,45,7754,39,5660,0.439949573,0.842259467,0.535493723,1.329962844,0.608283338,DB0915310061818_,0.49711449,-0.171667157,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,81730,DB11133,10061818,31,2400,26,1548,0.340936414,0.76910179,0.440031247,1.354298927,0.510170725,DB1113310061818_,0.673009854,-0.262531952,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,81732,DB00169,10066152,58,38633,23,18152,0.551953597,1.184840354,0.719342819,2.013393334,0.705801382,DB0016910066152_,0.34842141,0.169608043,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,cholecalciferol,DB00169
,81737,DB00338,10066152,72,33602,38,22234,0.284116644,1.253704814,0.834647106,1.910019794,0.448627635,DB0033810066152_,0.801562056,0.226103019,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,omeprazole,DB00338
,81740,DB00635,10066152,69,32984,25,23769,0.002352691,1.988882353,1.241911355,3.281791725,0.011101424,DB0063510066152_,4.500681852,0.687572849,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,prednisone,DB00635
,81741,DB00996,10066152,53,38900,28,22397,0.817521333,1.089837059,0.676793796,1.790034384,0.902479843,DB0099610066152_,0.102608924,0.086028198,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,gabapentin,DB00996
,81767,DB00295,10003246,35,14628,18,9584,0.482506381,1.273942969,0.701753672,2.390794364,0.646877497,DB0029510003246_,0.435598342,0.242116791,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,81769,DB00295,10012601,32,14631,26,9576,0.422329608,0.805554592,0.46478838,1.408272176,0.591371694,DB0029510012601_,0.525310536,-0.216224304,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,morphine,DB00295
,81782,DB08889,10003549,102,3063,132,3753,0.689137232,0.946794138,0.720627102,1.241110528,0.812504357,DB0888910003549_,0.207634002,-0.054673593,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,81786,DB00531,10045170,38,7214,96,6420,1.40980119826098e-08,0.35229168,0.234958599,0.518798529,3.061265964171e-07,DB0053110045170_,14.99926711,-1.043295811,male,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,cyclophosphamide,DB00531
,81787,DB01234,10045170,40,31585,81,32807,0.000493971,0.512940606,0.341999438,0.758356747,0.003061189,DB0123410045170_,5.788951774,-0.667595219,NA,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,81790,DB00531,10058080,35,7217,38,6478,0.480994449,0.826752906,0.506443971,1.346111181,0.64564165,DB0053110058080_,0.43751065,-0.190249412,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,81791,DB01234,10058080,55,31570,73,32815,0.184616326,0.783141454,0.541427132,1.127059293,0.329720848,DB0123410058080_,1.109508898,-0.244441943,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,81806,DB00016,10000081,47,2715,33,2257,0.498091654,1.183943627,0.739827382,1.914619835,0.660112392,DB0001610000081_,0.415345168,0.168850923,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,erythropoietin,DB00016
,81808,DB00658,10000081,30,1273,31,1365,0.897663357,1.037679021,0.602999934,1.783475019,0.956338178,DB0065810000081_,0.044643686,0.036986508,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,sevelamer,DB00658
,81812,DB00230,10007617,73,19601,24,8627,0.226545061,1.338668031,0.833410393,2.222319565,0.381579374,DB0023010007617_,0.963436393,0.291675113,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,pregabalin,DB00230
,81814,DB00722,10007617,106,25297,99,25933,0.529101753,1.097613322,0.826195699,1.459301583,0.686385096,DB0072210007617_,0.376316444,0.093138115,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,lisinopril,DB00722
,81823,DB00695,10034674,26,28023,30,20498,0.10374835,0.633960164,0.360020816,1.109391075,0.216619699,DB0069510034674_,1.529612002,-0.455769159,NA,10034674,Peritonitis,10021881,Infections and infestations,Infec,furosemide,DB00695
,81829,DB00230,10058080,49,19625,21,8630,1,1.026090256,0.603513073,1.802362353,1,DB0023010058080_,0,0.025755711,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,pregabalin,DB00230
,81831,DB00641,10058080,34,14090,36,12439,0.473281147,0.833786494,0.505807971,1.371787379,0.639220767,DB0064110058080_,0.447505396,-0.181777912,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,simvastatin,DB00641
,81860,DB00374,10044565,135,17581,28,5696,0.034843241,1.562004483,1.032514023,2.441134633,0.095124075,DB0037410044565_,2.352573184,0.445969922,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,81866,DB00635,10003827,33,33020,21,23773,0.681807615,1.131320611,0.635179166,2.058339156,0.807557371,DB0063510003827_,0.213741179,0.123385633,NA,10003827,Autoimmune hepatitis,10019805,Hepatobiliary disorders,Hepat,prednisone,DB00635
,81894,DB00158,10040979,30,16785,20,8084,0.290085858,0.722418723,0.396619494,1.343076085,0.455303111,DB0015810040979_,0.786791904,-0.325150359,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,81896,DB06413,10040979,54,1502,35,639,0.059986914,0.656514607,0.416649234,1.046114097,0.143458833,DB0641310040979_,1.941707163,-0.420810336,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,armodafinil,DB06413
,81898,DB01240,10033318,252,5499,98,1478,0.003290666,0.691177187,0.541134977,0.888342845,0.014585184,DB0124010033318_,4.227749069,-0.369359067,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,epoprostenol,DB01240
,81926,DB00559,10003445,51,9608,29,3277,0.038423833,0.599839285,0.372338355,0.983270744,0.102499029,DB0055910003445_,2.277901952,-0.511093518,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,81927,DB00559,10010774,111,9548,38,3268,1,0.999784499,0.684387423,1.489059223,1,DB0055910010774_,0,-0.000215524,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,81928,DB00203,10013946,179,13699,56,8882,7.6418390170118e-07,2.072396255,1.525226474,2.853906204,1.13036431379941e-05,DB0020310013946_,11.39038548,0.728705549,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,81929,DB00559,10013946,64,9595,13,3293,0.088515903,1.689457078,0.91988642,3.348413344,0.192770248,DB0055910013946_,1.646256225,0.524407222,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,81930,DB01240,10013946,108,5643,17,1559,0.028117865,1.75497716,1.042917698,3.13305978,0.080496443,DB0124010013946_,2.51954228,0.562455843,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,81932,DB01240,10022437,119,5632,36,1540,0.62117772,0.903860957,0.614982846,1.357420207,0.761528748,DB0124010022437_,0.272427355,-0.101079739,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,epoprostenol,DB01240
,81942,DB01136,10003285,39,9845,25,11090,0.032303106,1.757212831,1.036091954,3.032161703,0.089764999,DB0113610003285_,2.410560142,0.563728935,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,carvedilol,DB01136
,81959,DB00762,10021097,31,1132,25,1344,0.175304678,1.471984449,0.835677551,2.616943923,0.317828904,DB0076210021097_,1.146242079,0.386611456,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,irinotecan,DB00762
,81960,DB00526,10040047,24,1574,48,1846,0.041452901,0.58649202,0.341949402,0.981615093,0.108643195,DB0052610040047_,2.219686202,-0.533596217,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,oxaliplatin,DB00526
,81961,DB00544,10040047,35,2400,72,2581,0.001649399,0.522838339,0.337403332,0.796860191,0.008303066,DB0054410040047_,4.791130387,-0.648482966,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,fluorouracil,DB00544
,81962,DB00650,10040047,37,2094,79,1935,1.8996270624037e-05,0.432874099,0.283277286,0.650939744,0.000190943,DB0065010040047_,8.563533544,-0.837308357,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,leucovorin,DB00650
,81964,DB00112,10043071,37,5896,24,4067,0.89630472,1.06342908,0.618363811,1.861175262,0.956301489,DB0011210043071_,0.044682051,0.061498668,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,bevacizumab,DB00112
,81966,DB00544,10043071,31,2404,37,2616,0.716040939,0.911761722,0.545092515,1.515595124,0.831983737,DB0054410043071_,0.183942386,-0.092376593,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,fluorouracil,DB00544
,81967,DB00650,10043071,17,2114,33,1981,0.015100462,0.482827187,0.251375655,0.895345601,0.049589265,DB0065010043071_,3.003980906,-0.72809648,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,leucovorin,DB00650
,81973,DB00264,10047290,44,29563,55,24837,0.054745368,0.672122496,0.441433005,1.017971482,0.133921079,DB0026410047290_,2.010504614,-0.397314669,NA,10047290,Ventricular fibrillation,10007541,Cardiac disorders,Card,metoprolol,DB00264
,81981,DB01229,10020751,68,5673,16,2693,0.009497414,2.017350145,1.154872523,3.734108195,0.034164435,DB0122910020751_,3.37657008,0.701784841,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,paclitaxel,DB01229
,81996,DB00381,10023644,77,29283,32,22855,0.002581393,1.87800948,1.228088512,2.932916208,0.011963141,DB0038110023644_,4.425924912,0.630212428,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,amlodipine,DB00381
,81997,DB00996,10023644,65,38888,25,22400,0.099848148,1.497624544,0.930835322,2.480244074,0.210541781,DB0099610023644_,1.558071162,0.403880216,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,gabapentin,DB00996
,81999,DB00381,10038669,85,29275,73,22814,0.574319815,0.907406225,0.655534909,1.258747572,0.724098059,DB0038110038669_,0.322828455,-0.097165052,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,82001,DB00996,10038669,194,38759,158,22267,0.001267595,0.705426398,0.568451309,0.876438025,0.006685137,DB0099610038669_,5.007868527,-0.348952839,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,82004,DB00169,10038687,55,38636,27,18148,0.905719335,0.956832821,0.5930986,1.578298554,0.957861963,DB0016910038687_,0.0430516,-0.044126593,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,82005,DB00381,10038687,65,29295,61,22826,0.322950782,0.830277107,0.576078974,1.198000009,0.491389946,DB0038110038687_,0.71051728,-0.18599577,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,82006,DB01136,10038687,40,9844,30,11085,0.094324343,1.501380012,0.91121383,2.498296702,0.202261001,DB0113610038687_,1.598196331,0.406384693,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,82024,DB00741,10003239,138,3956,69,3105,0.002214735,1.569670361,1.162609498,2.135736602,0.010571924,DB0074110003239_,4.549553428,0.450865636,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocortisone,DB00741
,82026,DB00005,10022955,45,128037,45,42374,2.8260898118078e-07,0.330955117,0.2139674,0.511901601,4.63693949459225e-06,DB0000510022955_,12.281456,-1.105772512,male,10022955,Iritis,10015919,Eye disorders,Eye,etanercept,DB00005
,82027,DB00005,10005734,61,128021,13,42406,0.178011648,1.554243792,0.844728263,3.08421753,0.321329271,DB0000510005734_,1.135288915,0.44098912,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,etanercept,DB00005
,82037,DB00193,10003445,50,19270,18,8684,0.511797781,1.251765839,0.717201456,2.281319673,0.672126139,DB0019310003445_,0.397309249,0.224555226,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,82038,DB00381,10003445,61,29299,57,22830,0.353210682,0.833894677,0.5712908,1.21878786,0.522976638,DB0038110003445_,0.648218485,-0.181648171,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,82041,DB01076,10003445,37,25710,44,25539,0.43806738,0.835320183,0.524377397,1.324019145,0.606476097,DB0107610003445_,0.500089962,-0.179940174,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,82042,DB00423,10013968,82,2385,39,1001,0.543732419,0.882500295,0.591055013,1.337245027,0.698909806,DB0042310013968_,0.358233577,-0.124996155,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methocarbamol,DB00423
,82043,DB00051,10025310,53,25678,45,11375,0.001957112,0.521725576,0.343819767,0.794793868,0.009568065,DB0005110025310_,4.649324335,-0.650613547,NA,10025310,Lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,adalimumab,DB00051
,82049,DB00051,10035598,25,25706,30,11390,0.000331636,0.369249817,0.208113679,0.649856592,0.002191317,DB0005110035598_,6.123252505,-0.996281852,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,82051,DB00051,10047899,313,25418,76,11344,7.6548702442118e-07,1.838015968,1.424892765,2.39630754,1.13101891157452e-05,DB0005110047899_,11.38980655,0.608686712,NA,10047899,Weight increased,10022891,Investigations,Inv,adalimumab,DB00051
,82052,DB00193,10047899,294,19026,81,8621,4.91437045195498e-05,1.644619607,1.280129367,2.132942991,0.000435296,DB0019310047899_,7.73948322,0.497509116,NA,10047899,Weight increased,10022891,Investigations,Inv,tramadol,DB00193
,82054,DB00924,10040753,204,9958,35,4216,8.89937664798683e-08,2.467563145,1.714149272,3.647466907,1.62613913932801e-06,DB0092410040753_,13.32930198,0.903231083,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,cyclobenzaprine,DB00924
,82055,DB09153,10040753,337,7462,132,5567,1.87768802153638e-10,1.904577644,1.547953076,2.354398932,5.87210346770775e-09,DB0915310040753_,18.95305293,0.644260275,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,82056,DB00563,10056819,111,46535,34,15314,0.773051223,1.074366265,0.725475042,1.628390362,0.875903675,DB0056310056819_,0.132499155,0.071730967,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,82057,DB00005,10001551,55,128027,23,42396,0.359308353,0.791877226,0.478609232,1.350335051,0.529084342,DB0000510001551_,0.636607422,-0.233348916,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,etanercept,DB00005
,82060,DB00999,10010264,379,21051,143,12096,1.53903533121688e-05,1.522884514,1.251453777,1.861566152,0.000158436,DB0099910010264_,8.750159092,0.420606243,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,82062,DB00158,10020937,216,16599,67,8037,0.00137214,1.5609314,1.179937273,2.087932448,0.007144042,DB0015810020937_,4.941476544,0.445282694,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,82063,DB00635,10020937,372,32681,168,23626,2.66844855027305e-07,1.60075221,1.329487978,1.933818969,4.39750283034027e-06,DB0063510020937_,12.33447372,0.47047365,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,82065,DB01076,10020937,268,25479,186,25397,0.000157083,1.436206233,1.185752856,1.742543332,0.001173658,DB0107610020937_,6.747629953,0.362005077,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,82069,DB01409,10023232,49,5982,11,3955,0.000500891,2.944828435,1.508459415,6.288436127,0.003095532,DB0140910023232_,5.777795651,1.080050559,female,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,tiotropium,DB01409
,82070,DB00005,10042868,166,127916,44,42375,0.201697263,1.249789714,0.891486908,1.785033604,0.351111796,DB0000510042868_,1.046650599,0.222975308,NA,10042868,Synovitis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,82072,DB00563,10042868,235,46411,53,15295,0.011288706,1.461196597,1.079933854,2.008849177,0.03919472,DB0056310042868_,3.239213247,0.379255687,NA,10042868,Synovitis,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,82074,DB00635,10042868,54,32999,15,23779,0.000557007,2.59408422,1.442372162,4.950942164,0.003375429,DB0063510042868_,5.691232931,0.953233552,NA,10042868,Synovitis,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,82082,DB01076,10048959,525,25222,393,25190,1.70149669894308e-05,1.334170817,1.167001872,1.526218554,0.00017318,DB0107610048959_,8.661176678,0.288309988,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,82083,DB01409,10048959,128,5903,65,3901,0.087895966,1.301333102,0.955303016,1.78716253,0.191674242,DB0140910048959_,1.651958004,0.263389202,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,82097,DB00482,10022052,58,8201,6,3065,0.000635295,3.61267615,1.560709266,10.25804981,0.003780133,DB0048210022052_,5.577996213,1.284448814,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,82099,DB00331,10022094,50,24896,12,20740,2.93678817115418e-05,3.470921445,1.821989369,7.162868729,0.000278375,DB0033110022094_,8.186540272,1.244420105,female,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,82101,DB00451,10022094,82,47189,14,15405,0.023590724,1.911968963,1.07688357,3.651626309,0.070272232,DB0045110022094_,2.655378545,0.648133582,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,82113,DB08895,10020642,105,28009,21,6625,0.570311793,1.182649178,0.73451958,1.991575232,0.720916765,DB0889510020642_,0.327231592,0.167756988,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,82114,DB08895,10021425,89,28025,19,6627,0.806312774,1.107656806,0.668897793,1.926915054,0.895294503,DB0889510021425_,0.110602561,0.102246798,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,tofacitinib,DB08895
,82116,DB08895,10038683,55,28059,7,6639,0.144551191,1.859017948,0.843824372,4.841828636,0.27639967,DB0889510038683_,1.285907383,0.620048363,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,82118,DB00203,10013700,117,13761,108,8830,0.007346031,0.695170396,0.529826488,0.91280553,0.027822827,DB0020310013700_,3.581898476,-0.363598289,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,sildenafil,DB00203
,82119,DB08932,10013700,95,19348,14,6583,0.001869663,2.308859882,1.309417054,4.386098869,0.009208187,DB0893210013700_,4.687662338,0.836753845,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,macitentan,DB08932
,82122,DB00254,10028334,75,5860,28,3360,0.063129883,1.535769608,0.980678744,2.468123177,0.14918358,DB0025410028334_,1.902577648,0.429031628,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,doxycycline,DB00254
,82132,DB00186,10062355,115,16786,56,9952,0.234989437,1.217460335,0.876266118,1.708717499,0.392009478,DB0018610062355_,0.936469261,0.196766997,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,82133,DB00281,10062355,66,11392,33,5638,1,0.989814617,0.641439496,1.55414946,1,DB0028110062355_,0,-0.010237609,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,82134,DB00433,10062355,39,7617,33,5987,0.812140114,0.928922551,0.568510911,1.526120447,0.89905753,DB0043310062355_,0.106408254,-0.073729912,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,82135,DB00904,10062355,147,22922,97,14359,0.69259957,0.949342254,0.72900529,1.24090559,0.814832141,DB0090410062355_,0.204773149,-0.051985898,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,82139,DB00007,10011906,30,1917,379,4073,9.07394121562881e-32,0.168191145,0.111475771,0.245275702,2.27150995097908e-29,DB0000710011906_,65.95452291,-1.782654177,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,leuprolide,DB00007
,82151,DB00996,10029350,16,38937,46,22379,2.13864951359323e-09,0.19991919,0.105616239,0.359887188,5.55752866681146e-08,DB0099610029350_,16.70552722,-1.609842045,male,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,82154,DB00996,10058080,114,38839,65,22360,1,1.009706731,0.737795992,1.391881195,1,DB0099610058080_,0,0.009659923,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,82159,DB00363,10013710,82,4546,116,6772,0.715460578,1.053012153,0.781773251,1.413031308,0.831529947,DB0036310013710_,0.184487965,0.051654775,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,clozapine,DB00363
,82162,DB00736,10056819,43,10548,12,5541,0.06334688,1.882304655,0.974131352,3.924758294,0.149561909,DB0073610056819_,1.900044864,0.632496906,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,82163,DB00005,10069217,163,127919,59,42360,0.586534483,0.914854736,0.675181456,1.254397014,0.733726388,DB0000510069217_,0.309619088,-0.088989985,NA,10069217,Needle issue,10077536,Product issues,Prod,etanercept,DB00005
,82165,DB00047,10007554,35,9250,41,8477,0.301935719,0.782334021,0.483206873,1.260392714,0.468278285,DB0004710007554_,0.758692534,-0.245473493,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,insulin glargine,DB00047
,82173,DB06643,10010264,154,52267,20,7495,0.818326565,1.104184207,0.690143254,1.85938828,0.903048564,DB0664310010264_,0.101978946,0.099106788,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,82180,DB00153,10020947,46,7377,21,3418,1,1.014923382,0.59242901,1.7933758,1,DB0015310020947_,0,0.014813124,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,ergocalciferol,DB00153
,82184,DB06643,10020947,246,52175,171,7344,1.9966790403507e-48,0.202496666,0.165668435,0.248018731,1.14092844729605e-45,DB0664310020947_,103.4844868,-1.597031857,male,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,denosumab,DB06643
,82193,DB00230,10031252,38,19636,24,8627,0.168623585,0.695636432,0.406315114,1.213097661,0.309052117,DB0023010031252_,1.174245353,-0.362928123,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,pregabalin,DB00230
,82195,DB00264,10031252,36,29571,43,24849,0.14133252,0.703531853,0.43882644,1.121935693,0.27174758,DB0026410031252_,1.302881659,-0.351642125,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,metoprolol,DB00264
,82203,DB00526,10020751,20,1578,34,1860,0.216709726,0.693429806,0.3765815,1.24544921,0.369536161,DB0052610020751_,0.99550668,-0.366105262,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,oxaliplatin,DB00526
,82205,DB00526,10051792,40,1558,30,1864,0.068381191,1.594972734,0.963770096,2.665234614,0.158375153,DB0052610051792_,1.842788673,0.466856641,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,oxaliplatin,DB00526
,82209,DB00661,10011906,170,3358,94,1501,0.11637032,0.808447558,0.61989287,1.05938763,0.235681618,DB0066110011906_,1.445273463,-0.212639465,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,verapamil,DB00661
,82211,DB05351,10011906,56,2667,36,1095,0.048036085,0.638750498,0.410200943,1.00585942,0.121424099,DB0535110011906_,2.108465911,-0.448241357,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dexlansoprazole,DB05351
,82219,DB00736,10005750,95,10496,48,5505,0.860156594,1.038043505,0.724960194,1.50341124,0.934091433,DB0073610005750_,0.068180952,0.037337696,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,esomeprazole,DB00736
,82223,DB00736,10043071,52,10539,22,5531,0.462244856,1.240408963,0.739359549,2.147102863,0.629457637,DB0073610043071_,0.462896725,0.215441134,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,esomeprazole,DB00736
,82224,DB01076,10043071,97,25650,98,25485,0.942846966,0.983427027,0.734569009,1.316450055,0.981842735,DB0107610043071_,0.018324131,-0.016711842,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,82225,DB00480,10028164,288,67140,137,67525,1.22078756727056e-13,2.114221739,1.718651759,2.611175742,6.15900215080741e-12,DB0048010028164_,25.81310634,0.748686773,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,lenalidomide,DB00480
,82231,DB00635,10039486,48,33005,16,23778,0.007274982,2.161264919,1.205552443,4.078515553,0.027597474,DB0063510039486_,3.590031027,0.770693661,NA,10039486,Sarcoidosis,10021428,Immune system disorders,Immun,prednisone,DB00635
,82232,DB00480,10040753,489,66939,269,67393,5.30011982689678e-16,1.830153206,1.573313308,2.132516168,3.65652623753233e-14,DB0048010040753_,30.93967772,0.604399683,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,82233,DB00497,10040753,139,19128,62,16313,1.34198858897347e-05,1.911933171,1.406493187,2.624677763,0.000140591,DB0049710040753_,8.869658763,0.648114862,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,oxycodone,DB00497
,82235,DB00635,10056342,70,32983,56,23738,0.587886337,0.899632972,0.623756951,1.302707981,0.734892869,DB0063510056342_,0.308030546,-0.105768408,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,82236,DB00264,10046555,25,29582,65,24827,3.88453500882549e-07,0.322798782,0.194895906,0.519345697,6.15646684998359e-06,DB0026410046555_,11.99800751,-1.130726114,male,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,82243,DB00620,10028735,39,4789,12,3120,0.021096525,2.117165985,1.083962332,4.448730731,0.064483071,DB0062010028735_,2.741352551,0.750078395,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,triamcinolone,DB00620
,82246,DB00065,10016173,49,9415,24,4933,0.90176612,1.069733537,0.642994891,1.825127396,0.957082614,DB0006510016173_,0.043865565,0.067409587,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,infliximab,DB00065
,82258,DB01225,10035742,36,5008,32,4608,0.903716607,1.035147317,0.623833716,1.724708285,0.957417047,DB0122510035742_,0.043516196,0.034543752,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enoxaparin,DB01225
,82259,DB08910,10035742,19,16725,40,17448,0.012653051,0.495545647,0.270959112,0.876237572,0.0429475,DB0891010035742_,3.147776838,-0.702095807,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,82269,DB00924,10005750,83,10079,28,4223,0.348524546,1.24196902,0.79923875,1.98344792,0.518039476,DB0092410005750_,0.657703832,0.216698039,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,cyclobenzaprine,DB00924
,82271,DB00461,10016256,74,1016,13,312,0.066595057,1.74749955,0.945703331,3.482842304,0.155218769,DB0046110016256_,1.862919747,0.558185938,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,nabumetone,DB00461
,82272,DB08893,10016256,97,1988,66,992,0.06133412,0.733416089,0.525745896,1.028345921,0.145897498,DB0889310016256_,1.924850971,-0.310042086,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,mirabegron,DB08893
,82273,DB00316,10042209,266,65208,70,36883,1.6507243278849e-09,2.149341726,1.645575411,2.839259379,4.38940707723365e-08,DB0031610042209_,16.94148659,0.765161621,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,82276,DB00924,10042209,51,10111,7,4244,0.002292652,3.057711363,1.380314892,7.994225398,0.010874295,DB0092410042209_,4.521353526,1.117666716,female,10042209,Stress,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,82279,DB00575,10047895,93,5151,65,3764,0.807888368,1.045510102,0.751183577,1.462472959,0.896336842,DB0057510047895_,0.109438997,0.044504902,NA,10047895,Weight decreased,10022891,Investigations,Inv,clonidine,DB00575
,82297,DB00635,10000804,34,33019,36,23758,0.115236139,0.679568878,0.412389546,1.117644526,0.233992549,DB0063510000804_,1.452466006,-0.386296685,NA,10000804,Acute hepatic failure,10019805,Hepatobiliary disorders,Hepat,prednisone,DB00635
,82301,DB00635,10013395,34,33019,30,23764,0.447812758,0.815675803,0.484287641,1.380237642,0.61559324,DB0063510013395_,0.485168858,-0.203738304,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,82302,DB00641,10013395,18,14106,37,12438,0.002717954,0.428971929,0.229781193,0.773273942,0.012469153,DB0064110013395_,4.38449745,-0.846363795,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,82303,DB00722,10013395,38,25365,62,25970,0.027179223,0.62753096,0.407480222,0.955182811,0.078407055,DB0072210013395_,2.545841363,-0.46596227,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,82307,DB00437,10016825,40,6881,31,11515,0.001306649,2.159226451,1.315842384,3.573436414,0.00685945,DB0043710016825_,4.982127972,0.769750033,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,allopurinol,DB00437
,82308,DB00641,10016825,78,14046,33,12442,0.000264428,2.093602187,1.375874085,3.250812116,0.001820454,DB0064110016825_,6.308669206,0.738886117,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,simvastatin,DB00641
,82309,DB00437,10020646,31,6890,86,11460,0.016220582,0.599570327,0.383788931,0.914729334,0.052400664,DB0043710020646_,2.94883601,-0.511542001,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,allopurinol,DB00437
,82310,DB00635,10020646,59,32994,123,23671,2.71845264743823e-12,0.344140558,0.247795245,0.473359992,1.13962564334791e-10,DB0063510020646_,22.8951511,-1.066705105,male,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,82312,DB00635,10033647,62,32991,47,23747,0.846011926,0.949550842,0.639242233,1.418672721,0.922561545,DB0063510033647_,0.08060119,-0.051766204,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,82314,DB00635,10033661,234,32819,261,23533,1.12956388944643e-06,0.642895181,0.536117951,0.770553635,1.59369762931291e-05,DB0063510033661_,11.0468686,-0.441773584,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,82319,DB00437,10073508,58,6863,73,11473,0.123261281,1.328163401,0.923073014,1.903544494,0.246017144,DB0043710073508_,1.402354053,0.283797087,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,82320,DB00635,10073508,63,32990,46,23748,1,0.985884727,0.663241778,1.475287975,1,DB0063510073508_,0,-0.014215841,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,82322,DB01234,10013442,45,31580,27,32861,0.024724742,1.734245402,1.052784342,2.907493868,0.072888083,DB0123410013442_,2.618830121,0.550572392,NA,10013442,Disseminated intravascular coagulation,10005329,Blood and lymphatic system disorders,Blood,dexamethasone,DB01234
,82324,DB01234,10055798,97,31528,98,32790,0.885976172,1.029421881,0.769024727,1.377782469,0.952535694,DB0123410055798_,0.048627699,0.028997364,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,dexamethasone,DB01234
,82329,DB00005,10062242,104,127978,67,42352,3.94773301901189e-05,0.513659068,0.374209359,0.709265004,0.000360487,DB0000510062242_,7.928054861,-0.666195526,NA,10062242,Shoulder operation,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,82331,DB00158,10005724,53,16762,23,8081,0.714734112,1.110923029,0.668641296,1.900613425,0.830887691,DB0015810005724_,0.185260642,0.105191228,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,folic acid,DB00158
,82335,DB00761,10005724,182,15125,71,8554,0.008335482,1.449707738,1.094662156,1.937692855,0.030761409,DB0076110005724_,3.481494314,0.371361976,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,82336,DB00787,10005724,132,16868,64,17184,6.08634434568236e-07,2.101082288,1.546093675,2.880548113,9.22072398422252e-06,DB0078710005724_,11.594057,0.742452587,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,acyclovir,DB00787
,82337,DB01050,10005724,64,18044,17,9354,0.013244176,1.951578695,1.128450509,3.556689651,0.044533914,DB0105010005724_,3.11150427,0.668638632,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,ibuprofen,DB01050
,82338,DB08910,10005724,62,16682,30,17458,0.000499001,2.162742206,1.376488091,3.466702056,0.003086536,DB0891010005724_,5.780705747,0.771376956,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,pomalidomide,DB08910
,82340,DB00687,10028813,75,911,37,1048,2.49078117008646e-05,2.330940102,1.535210133,3.592505751,0.000240788,DB0068710028813_,8.331594812,0.846271663,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fludrocortisone,DB00687
,82341,DB00188,10037087,146,7740,92,8736,1.07467974692924e-05,1.791088291,1.367810064,2.355473709,0.000115534,DB0018810037087_,9.065949446,0.582823419,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,bortezomib,DB00188
,82342,DB00285,10037087,192,10759,29,3689,1.07694232313931e-05,2.270067689,1.527583978,3.486721093,0.000115666,DB0028510037087_,9.064800831,0.81980965,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,venlafaxine,DB00285
,82344,DB01050,10042772,92,18016,73,9298,0.008175429,0.65041342,0.472670927,0.897823502,0.030326158,DB0105010042772_,3.495744637,-0.430147087,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,82345,DB09153,10042772,65,7734,44,5655,0.77038348,1.080174318,0.724309153,1.624217301,0.874236414,DB0915310042772_,0.134404443,0.077122433,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,82351,DB00586,10021789,64,7045,28,2777,0.642802365,0.900999514,0.568110458,1.462603797,0.779212773,DB0058610021789_,0.249471134,-0.104250561,NA,10021789,Infection,10021881,Infections and infestations,Infec,diclofenac,DB00586
,82357,DB00874,10037087,81,3254,32,1944,0.049399118,1.512104219,0.988556865,2.362860672,0.123896552,DB0087410037087_,2.08830832,0.413502203,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,guaifenesin,DB00874
,82360,DB01394,10013700,51,1389,23,1980,2.23462922554843e-06,3.159811402,1.886028033,5.444552665,2.92297731741929e-05,DB0139410013700_,10.44032274,1.150512343,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,colchicine,DB01394
,82366,DB00404,10012374,81,19811,30,9832,0.189419253,1.340001997,0.870858065,2.112366909,0.335809872,DB0040410012374_,1.091210137,0.292671104,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,82368,DB00404,10012601,61,19831,17,9845,0.03979246,1.781329979,1.026361014,3.25523381,0.105273495,DB0040410012601_,2.251193597,0.577360264,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,alprazolam,DB00404
,82371,DB00404,10013538,48,19844,15,9847,0.140006762,1.587882849,0.873576019,3.05457159,0.269842069,DB0040410013538_,1.309918419,0.462401588,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,alprazolam,DB00404
,82382,DB00404,10042209,147,19745,25,9837,3.44678664165257e-08,2.929340287,1.906540216,4.67715889,6.87917895792239e-07,DB0040410042209_,14.18959634,1.07477724,female,10042209,Stress,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,82392,DB00999,10069326,69,21361,34,12205,0.538603976,1.159563086,0.757886015,1.804753611,0.694508353,DB0099910069326_,0.36455109,0.148043284,NA,10069326,Product substitution issue,10077536,Product issues,Prod,hydrochlorothiazide,DB00999
,82441,DB00005,10037368,86,127996,20,42399,0.177204875,1.424357011,0.867710544,2.447379511,0.320301894,DB0000510037368_,1.13849131,0.353720492,NA,10037368,Pulmonary congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,82458,DB01373,10069327,65,22655,14,7367,0.190123638,1.509719404,0.837921985,2.915044292,0.336717974,DB0137310069327_,1.088509571,0.411923809,NA,10069327,Product quality issue,10077536,Product issues,Prod,calcium,DB01373
,82461,DB00480,10038687,27,67401,36,67626,0.313435768,0.752507664,0.439343462,1.274706044,0.480975632,DB0048010038687_,0.73193867,-0.284344098,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,82463,DB00864,10013968,136,6733,168,8224,0.953596325,0.988790247,0.780987996,1.250037293,0.991545528,DB0086410013968_,0.008490414,-0.011273056,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tacrolimus,DB00864
,82465,DB00381,10020100,98,29262,57,22830,0.088388782,1.341375137,0.957590707,1.894302202,0.192546999,DB0038110020100_,1.647415007,0.293695309,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,82467,DB00635,10020100,75,32978,45,23749,0.355251497,1.200229803,0.818229553,1.778363446,0.525007624,DB0063510020100_,0.644342494,0.182513041,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,82468,DB00722,10020100,95,25308,43,25989,4.85093017001976e-06,2.268725644,1.565900506,3.33441707,5.75889327313667e-05,DB0072210020100_,9.762180149,0.819218284,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,82493,DB00381,10059168,41,29319,14,22873,0.006200776,2.284634386,1.219702768,4.538734372,0.024297466,DB0038110059168_,3.717383219,0.826206005,NA,10059168,Oxygen consumption increased,10022891,Investigations,Inv,amlodipine,DB00381
,82501,DB08932,10059168,192,19251,66,6531,0.942661652,0.986924122,0.74135077,1.327986063,0.981718542,DB0893210059168_,0.018450629,-0.01316212,NA,10059168,Oxygen consumption increased,10022891,Investigations,Inv,macitentan,DB08932
,82504,DB00451,10001488,43,47228,50,15369,1.68333278620799e-09,0.27987278,0.18170292,0.429558185,4.46707746446007e-08,DB0045110001488_,16.92394636,-1.273420137,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,82505,DB00502,10001488,31,1363,47,1825,0.643974403,0.883199783,0.539291493,1.428115423,0.780219736,DB0050210001488_,0.248179686,-0.124203849,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,haloperidol,DB00502
,82510,DB00813,10003054,39,10533,13,10155,0.000455303,2.892441179,1.510162448,5.908627743,0.002856576,DB0081310003054_,5.858131399,1.062100844,female,10003054,Application site rash,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,82512,DB04861,10011906,51,1914,60,1327,0.007866811,0.589426993,0.39491278,0.876858706,0.029380381,DB0486110011906_,3.527428142,-0.528604412,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,nebivolol,DB04861
,82514,DB04861,10035664,65,1900,57,1330,0.224914017,0.798307102,0.546663131,1.168484732,0.379683693,DB0486110035664_,0.96841676,-0.225261915,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,nebivolol,DB04861
,82519,DB09065,10037844,37,715,93,1844,0.920266123,1.026053091,0.67446508,1.533566173,0.964711792,DB0906510037844_,0.035925884,0.025719491,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cobicistat,DB09065
,82530,DB00005,10020028,51,128031,7,42412,0.022284271,2.413605754,1.090440995,6.304341721,0.067260958,DB0000510020028_,2.699175329,0.881121793,NA,10020028,Hiatus hernia,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,82533,DB00761,10001551,87,15220,48,8577,0.928677139,1.021406638,0.709249932,1.48639852,0.970364828,DB0076110001551_,0.030083167,0.021180734,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,potassium chloride,DB00761
,82535,DB00787,10001551,25,16975,42,17206,0.049977054,0.603350437,0.352229699,1.013715783,0.12495452,DB0078710001551_,2.079805452,-0.505257095,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,acyclovir,DB00787
,82537,DB00761,10003481,111,15196,50,8575,0.216513744,1.252754636,0.888434568,1.788078509,0.369297802,DB0076110003481_,0.99615191,0.225344835,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,potassium chloride,DB00761
,82539,DB00787,10003481,30,16970,45,17203,0.105645364,0.675830954,0.410866219,1.097184402,0.219608751,DB0078710003481_,1.515907719,-0.391812302,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,acyclovir,DB00787
,82540,DB00773,10003658,17,2306,40,2787,0.022371043,0.513719437,0.27231749,0.929861984,0.067454224,DB0077310003658_,2.69630608,-0.666078004,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,etoposide,DB00773
,82542,DB00381,10005364,52,29308,47,22840,0.478974586,0.862219089,0.569666813,1.308040941,0.644163166,DB0038110005364_,0.439803221,-0.148245877,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,amlodipine,DB00381
,82544,DB00787,10005364,34,16966,42,17206,0.422603113,0.820981259,0.506304487,1.322522564,0.591581341,DB0078710005364_,0.524956089,-0.197254997,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,acyclovir,DB00787
,82545,DB01076,10005364,33,25714,61,25522,0.003706859,0.536953923,0.340361264,0.833570125,0.016042217,DB0107610005364_,4.132531441,-0.621842992,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,atorvastatin,DB01076
,82549,DB00381,10016326,59,29301,35,22852,0.21285033,1.314689161,0.85079441,2.05899535,0.364836708,DB0038110016326_,1.008305401,0.273600258,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,82553,DB01076,10016326,49,25698,39,25544,0.337201473,1.248873065,0.803054161,1.954018149,0.506346409,DB0107610016326_,0.68053424,0.222241597,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,82558,DB00787,10019301,44,16956,34,17214,0.257393566,1.313794045,0.820311456,2.120658047,0.418300351,DB0078710019301_,0.871555561,0.272919169,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,acyclovir,DB00787
,82559,DB01076,10019301,54,25693,57,25526,0.776156128,0.9411882,0.636227299,1.39087715,0.877974152,DB0107610019301_,0.130138125,-0.06061216,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,82561,DB00773,10021097,67,2256,101,2726,0.180404284,0.80160247,0.576582733,1.10842785,0.324345185,DB0077310021097_,1.125946944,-0.221142467,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,etoposide,DB00773
,82562,DB00531,10022437,50,7202,36,6480,0.330753257,1.249631152,0.796925041,1.977239118,0.499459934,DB0053110022437_,0.694227895,0.222848429,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,cyclophosphamide,DB00531
,82565,DB00773,10028813,139,2184,150,2677,0.301391202,1.135815656,0.888810801,1.450663878,0.467654531,DB0077310028813_,0.760025437,0.127351033,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,etoposide,DB00773
,82566,DB01076,10033661,80,25667,105,25478,0.065401685,0.756301035,0.557928592,1.021880266,0.1531371,DB0107610033661_,1.876421683,-0.279315787,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,atorvastatin,DB01076
,82577,DB00787,10061818,77,16923,117,17131,0.006095627,0.666219767,0.492676336,0.896571934,0.023971209,DB0078710061818_,3.730901788,-0.406135683,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,82578,DB00381,10017412,102,29258,60,22827,0.095540682,1.326326263,0.954419399,1.857129204,0.204063616,DB0038110017412_,1.589323492,0.282412912,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,amlodipine,DB00381
,82581,DB00761,10017412,51,15256,29,8596,1,0.990893816,0.615736308,1.622675244,1,DB0076110017412_,0,-0.009147899,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,potassium chloride,DB00761
,82583,DB00787,10017412,55,16945,76,17172,0.080629034,0.733388097,0.508374697,1.052069438,0.179422127,DB0078710017412_,1.718013996,-0.310080254,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,acyclovir,DB00787
,82584,DB01076,10017412,73,25674,60,25523,0.297772318,1.209504664,0.847366103,1.732160549,0.463683387,DB0107610017412_,0.768553315,0.190210907,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,atorvastatin,DB01076
,82586,DB01020,10047700,66,1747,38,1840,0.003720611,1.828992365,1.201919158,2.818333064,0.016086234,DB0102010047700_,4.129791428,0.603765195,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,isosorbide mononitrate,DB01020
,82587,DB00736,10007515,39,10552,32,5521,0.061060684,0.637669439,0.388817981,1.05277899,0.145404971,DB0073610007515_,1.928232528,-0.449935251,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,esomeprazole,DB00736
,82588,DB00404,10019303,119,19773,51,9811,0.414387094,1.157740191,0.826496525,1.641988832,0.583651467,DB0040410019303_,0.538451278,0.146469994,NA,10019303,Heart rate increased,10022891,Investigations,Inv,alprazolam,DB00404
,82589,DB00736,10019303,60,10531,29,5524,0.823037225,1.085260798,0.684763518,1.756003824,0.906059659,DB0073610019303_,0.098650126,0.081820325,NA,10019303,Heart rate increased,10022891,Investigations,Inv,esomeprazole,DB00736
,82590,DB01409,10019303,53,5978,16,3950,0.004399777,2.18859179,1.229946978,4.107806721,0.018447917,DB0140910019303_,3.99280379,0.783258319,NA,10019303,Heart rate increased,10022891,Investigations,Inv,tiotropium,DB01409
,82596,DB00043,10002424,70,6343,22,2278,0.636025136,1.142685811,0.697171154,1.942897433,0.773792526,DB0004310002424_,0.256451496,0.133381466,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,omalizumab,DB00043
,82603,DB00668,10073317,86,10005,40,4263,0.626632686,0.916096003,0.621399185,1.371011126,0.766166162,DB0066810073317_,0.266356212,-0.087634113,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,epinephrine,DB00668
,82604,DB00455,10022086,89,9312,20,5098,0.000118403,2.436092868,1.485098157,4.183520507,0.00092127,DB0045510022086_,6.98975789,0.890395472,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,82605,DB14500,10022086,65,7744,8,4065,9.17838390830135e-06,4.264281235,2.038250397,10.30456867,0.000100774,DB1450010022086_,9.202626587,1.45027364,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,82606,DB00455,10022095,45,9356,10,5108,0.006965966,2.456688383,1.219261294,5.472807686,0.026686755,DB0045510022095_,3.623587913,0.898814257,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,82612,DB00390,10003239,79,4066,30,3271,0.000306134,2.118218777,1.371365158,3.350042844,0.00205148,DB0039010003239_,6.189193713,0.750575536,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,digoxin,DB00390
,82614,DB00338,10009033,233,33441,149,22123,0.793198549,1.034511493,0.838037657,1.280240486,0.887894288,DB0033810009033_,0.118902588,0.033929328,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,82615,DB00390,10009033,52,4093,56,3245,0.119074461,0.736224927,0.493374329,1.096834895,0.239910487,DB0039010009033_,1.427489394,-0.306219599,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,82616,DB01067,10009033,32,4329,32,4791,0.707814164,1.1067093,0.655251969,1.869226441,0.825398518,DB0106710009033_,0.191888957,0.101391017,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glipizide,DB01067
,82617,DB01275,10009033,41,3938,25,3324,0.21606283,1.384233771,0.819966147,2.380714084,0.368696171,DB0127510009033_,0.997782358,0.325146752,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydralazine,DB01275
,82619,DB00193,10016807,98,19222,21,8681,0.001368845,2.107502438,1.304463112,3.558529483,0.007133953,DB0019310016807_,4.942889792,0.745503568,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,tramadol,DB00193
,82620,DB00761,10016807,263,15044,121,8504,0.068365613,1.228687859,0.98524914,1.539313202,0.158346049,DB0076110016807_,1.842972459,0.205946819,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,82621,DB01275,10016807,36,3943,27,3322,0.704065242,1.123302844,0.661662122,1.928223843,0.822564291,DB0127510016807_,0.195328634,0.116273314,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,hydralazine,DB01275
,82624,DB00338,10017888,45,33629,25,22247,0.542146193,1.19074058,0.71451846,2.026955571,0.6973995,DB0033810017888_,0.360396862,0.17457545,NA,10017888,Gastroenteritis,10021881,Infections and infestations,Infec,omeprazole,DB00338
,82629,DB00695,10017888,48,28001,13,20515,0.000687629,2.705094388,1.442145543,5.443451184,0.004033097,DB0069510017888_,5.513220709,0.995136806,NA,10017888,Gastroenteritis,10021881,Infections and infestations,Infec,furosemide,DB00695
,82635,DB01275,10028813,186,3793,107,3242,0.001220134,1.485713591,1.159370479,1.911718463,0.006484931,DB0127510028813_,5.038274117,0.39589519,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,hydralazine,DB01275
,82636,DB04854,10028813,52,729,58,1428,0.005250405,1.755815099,1.170671185,2.627641081,0.021271101,DB0485410028813_,3.850405885,0.562933193,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,febuxostat,DB04854
,82641,DB01240,10005488,53,5698,20,1556,0.250788384,0.723692608,0.423950301,1.282093918,0.410599686,DB0124010005488_,0.890136538,-0.323388551,NA,10005488,Blood culture positive,10022891,Investigations,Inv,epoprostenol,DB01240
,82642,DB00559,10058080,63,9596,17,3289,0.4410388,1.270146346,0.732833742,2.319014207,0.609222901,DB0055910058080_,0.495571067,0.239132127,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,bosentan,DB00559
,82643,DB00820,10058080,69,11846,25,5791,0.225973601,1.349255454,0.841788386,2.228269095,0.380848686,DB0082010058080_,0.965353133,0.299552925,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,tadalafil,DB00820
,82644,DB01240,10058080,75,5676,18,1558,0.703590322,1.143683223,0.674371195,2.039802663,0.822205647,DB0124010058080_,0.195764736,0.134253951,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,82645,DB00005,10048049,93,127989,10,42409,0.000142465,3.081645283,1.602691226,6.637018358,0.001079318,DB0000510048049_,6.831426164,1.125463637,female,10048049,Wrist fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,82647,DB06605,10007559,204,13869,181,12852,0.681422211,1.044434771,0.849495138,1.284873186,0.807428338,DB0660510007559_,0.213900974,0.04347585,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,apixaban,DB06605
,82649,DB01296,10013968,47,1402,31,952,1,1.029487192,0.635213996,1.689538339,1,DB0129610013968_,0,0.029060807,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glucosamine,DB01296
,82650,DB11097,10013968,34,820,20,663,0.329193406,1.374231726,0.760498731,2.544937658,0.497833766,DB1109710013968_,0.697489061,0.31789483,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,plantago seed,DB11097
,82652,DB06605,10035598,109,13964,77,12956,0.076940929,1.313383552,0.971038181,1.783766525,0.173070398,DB0660510035598_,1.754056841,0.272606671,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,82662,DB00559,10005724,71,9588,19,3287,0.395952571,1.281044697,0.762079678,2.254999743,0.565585051,DB0055910005724_,0.569894595,0.247675915,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,bosentan,DB00559
,82663,DB06228,10005724,50,15862,20,16056,0.00028152,2.530624352,1.478771599,4.489633072,0.001917533,DB0622810005724_,6.256715671,0.928466052,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,rivaroxaban,DB06228
,82664,DB08931,10005724,103,6474,25,2421,0.056740154,1.540702705,0.984606225,2.496376484,0.13733735,DB0893110005724_,1.985314968,0.432238615,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,riociguat,DB08931
,82665,DB00559,10061394,47,9612,13,3293,0.555334267,1.238576197,0.658243306,2.498541974,0.708750207,DB0055910061394_,0.344252133,0.213962492,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,bosentan,DB00559
,82668,DB08931,10064911,353,6224,101,2345,0.017060126,1.316745797,1.046939199,1.66808984,0.054541138,DB0893110064911_,2.908800044,0.275163388,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,82672,DB06282,10019211,100,1440,21,512,0.031732874,1.692747265,1.036440947,2.885316612,0.088503218,DB0628210019211_,2.424716362,0.52635281,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,levocetirizine,DB06282
,82675,DB00924,10043607,74,10088,47,4204,0.027395421,0.656153181,0.448337106,0.968698222,0.078866288,DB0092410043607_,2.540001416,-0.421361009,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,cyclobenzaprine,DB00924
,82676,DB01050,10043607,101,18007,55,9316,0.799505738,0.950053002,0.67677828,1.345914447,0.891657918,DB0105010043607_,0.11467272,-0.051237504,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,ibuprofen,DB01050
,82679,DB09153,10043607,38,7761,26,5673,0.899193242,1.068337857,0.631120049,1.834702186,0.956490275,DB0915310043607_,0.044484657,0.066104036,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,sodium chloride,DB09153
,82681,DB00480,10018830,22,67406,36,67626,0.086908718,0.613111473,0.343549441,1.070963678,0.189883683,DB0048010018830_,1.661343591,-0.489208511,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,82682,DB00480,10045170,29,67399,32,67630,0.798125967,0.909367891,0.530713274,1.552126263,0.89089269,DB0048010045170_,0.115531297,-0.095005546,NA,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,82687,DB00316,10014184,46,65428,30,36923,0.551374157,0.865313098,0.534560339,1.41999935,0.70542077,DB0031610014184_,0.348960817,-0.144663875,NA,10014184,Eczema,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,82688,DB00451,10014184,63,47208,14,15405,0.233001277,1.468409608,0.813568708,2.838919292,0.389533381,DB0045110014184_,0.942805716,0.384179916,NA,10014184,Eczema,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,82714,DB01254,10028334,46,3421,30,3118,0.166619548,1.397451445,0.860969254,2.298920097,0.30627608,DB0125410028334_,1.183268361,0.334650181,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,dasatinib,DB01254
,82716,DB00165,10013573,77,2068,32,1334,0.045441,1.552008928,1.008779928,2.437495738,0.116409207,DB0016510013573_,2.150643645,0.439550174,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pyridoxine,DB00165
,82718,DB00165,10028813,139,2006,50,1316,0.00029189,1.823472493,1.300289706,2.592156883,0.001973084,DB0016510028813_,6.228157231,0.600742646,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pyridoxine,DB00165
,82719,DB00165,10033371,78,2067,20,1346,8.84125792405788e-05,2.539022381,1.529107768,4.403988055,0.00071848,DB0016510033371_,7.238372222,0.931779117,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,pyridoxine,DB00165
,82720,DB00698,10035664,88,3060,14,415,0.538139744,0.852525739,0.476592886,1.638457356,0.694140288,DB0069810035664_,0.365081195,-0.159551878,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,nitrofurantoin,DB00698
,82722,DB01254,10028810,30,3437,25,3123,0.787511593,1.090323152,0.618365381,1.938133233,0.884872849,DB0125410028810_,0.122311318,0.086474122,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,dasatinib,DB01254
,82738,DB00734,10019070,43,4007,60,4842,0.487705805,0.866024986,0.570051539,1.305828667,0.651449966,DB0073410019070_,0.428554683,-0.143841519,NA,10019070,"Hallucination, auditory",10037175,Psychiatric disorders,Psych,risperidone,DB00734
,82739,DB00734,10022998,37,4013,29,4873,0.082722334,1.5491878,0.925297888,2.616877932,0.182928312,DB0073410022998_,1.698660941,0.437730793,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,82746,DB00374,10061024,155,17561,60,5664,0.232085588,0.833193045,0.613691655,1.143895167,0.388434873,DB0037410061024_,0.94562976,-0.182489916,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,treprostinil,DB00374
,82754,DB00695,10022004,151,27898,50,20478,2.9940191026486e-07,2.216718836,1.5992866,3.118292874,4.8804832318213e-06,DB0069510022004_,12.23026632,0.796028101,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,82764,DB00695,10037383,38,28011,18,20510,0.137604258,1.545766386,0.860516571,2.878204821,0.26635207,DB0069510037383_,1.322936275,0.43551983,NA,10037383,Pulmonary fibrosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,82767,DB06403,10024690,138,21333,53,6608,0.199785995,0.80653429,0.582810884,1.130479087,0.348801094,DB0640310024690_,1.05325345,-0.215008866,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,ambrisentan,DB06403
,82768,DB00243,10016256,62,1192,53,1573,0.02690622,1.54345467,1.043684534,2.289315774,0.077811639,DB0024310016256_,2.553464262,0.434023196,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ranolazine,DB00243
,82779,DB00005,10003481,49,128033,14,42405,0.770610305,1.159209347,0.629730795,2.273847435,0.874325198,DB0000510003481_,0.134302893,0.147738175,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,etanercept,DB00005
,82782,DB00734,10054112,72,3978,73,4829,0.312850877,1.19726966,0.849989447,1.686076817,0.480374174,DB0073410054112_,0.73318995,0.180043681,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,risperidone,DB00734
,82788,DB04868,10035598,28,1613,39,1477,0.107792533,0.65750739,0.3875431,1.102430384,0.222745811,DB0486810035598_,1.501724018,-0.419299276,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nilotinib,DB04868
,82808,DB00295,10005724,56,14607,26,9576,0.174320958,1.411990285,0.871274791,2.344383843,0.316536656,DB0029510005724_,1.150316226,0.345000259,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,morphine,DB00295
,82814,DB01590,10013911,67,4671,31,2836,0.248464987,1.312183212,0.842766096,2.084054722,0.407850009,DB0159010013911_,0.896855797,0.271692324,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,everolimus,DB01590
,82825,DB00381,10043458,35,29325,15,22872,0.062745355,1.819847722,0.968227958,3.587701743,0.148582132,DB0038110043458_,1.906617394,0.598752829,NA,10043458,Thirst,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,82838,DB00688,10066260,27,6463,35,5343,0.095668242,0.63777697,0.370783837,1.086039053,0.204284476,DB0068810066260_,1.588241768,-0.449766633,NA,10066260,Acute graft versus host disease,10021428,Immune system disorders,Immun,mycophenolate mofetil,DB00688
,82839,DB00996,10029202,56,38897,27,22398,0.494810045,1.194275383,0.741584406,1.967214097,0.657228907,DB0099610029202_,0.419722909,0.177539627,NA,10029202,Nervous system disorder,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,82840,DB08895,10027175,244,27870,39,6607,0.022495573,1.483151183,1.053250899,2.139074794,0.067708248,DB0889510027175_,2.692547276,0.394169002,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,82841,DB00480,10009866,31,67397,23,67639,0.279717858,1.352657738,0.763446835,2.429545827,0.443542599,DB0048010009866_,0.812961431,0.302071352,NA,10009866,Cold sweat,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,82845,DB00480,10045555,23,67405,32,67630,0.280551334,0.721153815,0.402936112,1.271670182,0.444395071,DB0048010045555_,0.811041312,-0.326902829,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,82847,DB00843,10011906,169,2025,231,1942,0.000930646,0.701676932,0.566327835,0.868058386,0.005190328,DB0084310011906_,5.2609583,-0.354282192,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,donepezil,DB00843
,82848,DB01162,10011906,12,261,99,1603,0.39749905,0.744558654,0.366852272,1.3843027,0.567223807,DB0116210011906_,0.567001333,-0.294963646,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,terazosin,DB01162
,82850,DB00678,10005557,145,15454,109,10615,0.480972716,0.913739784,0.706879676,1.183995007,0.64564165,DB0067810005557_,0.43751065,-0.090209449,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,losartan,DB00678
,82851,DB01016,10013709,57,1044,55,1173,0.439467696,1.164341871,0.781780078,1.735345614,0.60790361,DB0101610013709_,0.497738946,0.152156009,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,glyburide,DB01016
,82857,DB06769,10037844,35,632,54,1002,0.911367547,1.027601259,0.643864285,1.621974031,0.960195795,DB0676910037844_,0.040618062,0.027227211,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,bendamustine,DB06769
,82875,DB00264,10041569,36,29571,27,24865,0.705187824,1.121118023,0.661731868,1.920663171,0.823303809,DB0026410041569_,0.194429998,0.114326422,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,82877,DB00695,10041569,54,27995,34,20494,0.518578597,1.162654872,0.74301171,1.842560886,0.677830797,DB0069510041569_,0.388857584,0.150706073,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,82878,DB00904,10041569,36,23033,26,14430,0.602628326,0.867458169,0.509185835,1.496844296,0.746504809,DB0090410041569_,0.29235322,-0.142187989,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,82880,DB01076,10041569,36,25711,35,25548,1,1.022053708,0.623528748,1.676909828,1,DB0107610041569_,0,0.021814042,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,82892,DB00763,10020850,31,739,24,277,0.012923521,0.484513034,0.269877959,0.879212184,0.043675562,DB0076310020850_,3.13096655,-0.724610946,NA,10020850,Hyperthyroidism,10014698,Endocrine disorders,Endo,methimazole,DB00763
,82893,DB01118,10020850,29,3034,158,4551,1.0075646211341e-12,0.275355491,0.178093406,0.412322523,4.51557307186866e-11,DB0111810020850_,23.82090392,-1.289692323,male,10020850,Hyperthyroidism,10014698,Endocrine disorders,Endo,amiodarone,DB01118
,82907,DB00470,10012735,65,854,55,898,0.258727894,1.2425603,0.843255436,1.836430259,0.419819908,DB0047010012735_,0.86792945,0.217174009,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dronabinol,DB00470
,82908,DB08875,10012735,105,538,157,1086,0.029544091,1.349737514,1.021713913,1.778303825,0.08370879,DB0887510012735_,2.480411294,0.299910139,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cabozantinib,DB08875
,82909,DB08875,10047700,31,612,66,1177,0.74160611,0.903359694,0.56315866,1.421852341,0.851841572,DB0887510047700_,0.160354718,-0.101634473,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cabozantinib,DB08875
,82911,DB01069,10053762,192,6508,67,2328,0.942946209,1.025099654,0.769026831,1.38053954,0.981889317,DB0106910053762_,0.018276688,0.024789832,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,promethazine,DB01069
,82912,DB00470,10061428,62,857,62,891,0.852944353,1.039665203,0.70977511,1.522801805,0.928138201,DB0047010061428_,0.074574634,0.038898741,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,dronabinol,DB00470
,82913,DB08875,10061428,39,604,65,1178,0.457546824,1.170087588,0.756257342,1.790427031,0.624889237,DB0887510061428_,0.470180865,0.157078608,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,cabozantinib,DB08875
,82937,DB00335,10017413,50,8416,29,5436,0.729150498,1.113656352,0.690168254,1.827662218,0.842208637,DB0033510017413_,0.171727508,0.107648612,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,atenolol,DB00335
,82938,DB00338,10017413,206,33468,156,22116,0.215358043,0.872613548,0.704769436,1.082205512,0.367839765,DB0033810017413_,1.000107856,-0.136262492,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,omeprazole,DB00338
,82939,DB00437,10017413,63,6858,102,11444,0.871783752,1.030691993,0.739506316,1.426937446,0.943618675,DB0043710017413_,0.05803314,0.030230415,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,allopurinol,DB00437
,82940,DB00641,10017413,76,14048,84,12391,0.176632438,0.798052451,0.576753789,1.102674128,0.319541872,DB0064110017413_,1.140866958,-0.225580956,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,simvastatin,DB00641
,82941,DB00722,10017413,120,25283,99,25933,0.119208344,1.243275564,0.944265627,1.640096592,0.240139206,DB0072210017413_,1.426536498,0.217749481,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,lisinopril,DB00722
,82943,DB00996,10017413,211,38742,130,22295,0.535692748,0.934039815,0.746681623,1.172090704,0.692197615,DB0099610017413_,0.367883793,-0.068236214,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,gabapentin,DB00996
,82949,DB01254,10003239,85,3382,58,3090,0.091083983,1.338923588,0.944109138,1.910218141,0.196990325,DB0125410003239_,1.624600663,0.291865999,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,dasatinib,DB01254
,82950,DB01254,10003549,40,3427,41,3107,0.654628501,0.884528265,0.556027834,1.40615335,0.78836755,DB0125410003549_,0.237790863,-0.12270081,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,dasatinib,DB01254
,82960,DB00678,10008469,108,15491,65,10659,0.437718895,1.143221117,0.831916095,1.581703789,0.606171659,DB0067810008469_,0.500592068,0.133849819,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,82963,DB13961,10008469,48,9409,39,6375,0.443406113,0.833913498,0.534434793,1.308404473,0.611550514,DB1396110008469_,0.491757721,-0.181625601,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,82970,DB00213,10001760,218,18677,30,13391,3.87727812247865e-24,5.209823027,3.543491486,7.91344299,5.63062184803046e-22,DB0021310001760_,48.92865216,1.650545887,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,82974,DB14513,10001760,132,7045,10,3554,1.07398092178413e-13,6.658713477,3.502701394,14.22698533,5.47085049013483e-12,DB1451310001760_,25.93158703,1.895926294,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,magnesium,DB14513
,82975,DB00660,10016256,54,1203,15,352,1,1.053305242,0.577305725,2.035240043,1,DB0066010016256_,0,0.051933069,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,metaxalone,DB00660
,83002,DB00660,10028813,66,1191,16,351,0.588061344,1.215534648,0.685334804,2.279020118,0.735059201,DB0066010028813_,0.307804237,0.19518402,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,metaxalone,DB00660
,83004,DB00737,10037087,69,2732,19,913,0.533659236,1.213560835,0.717122597,2.14822802,0.6902996,DB0073710037087_,0.370629573,0.193558877,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,meclizine,DB00737
,83018,DB00572,10021097,68,2834,67,2059,0.093047482,0.737434018,0.515810794,1.054525296,0.200168028,DB0057210021097_,1.608598123,-0.304578662,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,atropine,DB00572
,83019,DB00788,10021097,105,9251,81,4980,0.016520416,0.697810944,0.51615084,0.9463697,0.053133748,DB0078810021097_,2.934943002,-0.359807067,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,naproxen,DB00788
,83020,DB08910,10021097,121,16623,130,17358,0.849344609,0.971919584,0.75171073,1.255913192,0.925044462,DB0891010021097_,0.077913475,-0.028482211,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,pomalidomide,DB08910
,83023,DB00331,10038153,74,24872,46,20706,0.141582615,1.339232586,0.914157752,1.980255109,0.272007703,DB0033110038153_,1.301924893,0.292096753,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,metformin,DB00331
,83026,DB00836,10038153,35,5500,23,4052,0.692008613,1.121130773,0.642865132,1.990545721,0.814300902,DB0083610038153_,0.205425323,0.114337795,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,loperamide,DB00836
,83027,DB01076,10038153,81,25666,77,25506,0.811320768,1.045403609,0.755325542,1.447880828,0.898580697,DB0107610038153_,0.106938764,0.04440304,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,83028,DB08910,10038153,91,16653,96,17392,1,0.989981384,0.73429258,1.333856361,1,DB0891010038153_,0,-0.01006914,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,pomalidomide,DB08910
,83030,DB00213,10047942,260,18635,194,13227,0.59823283,0.951295575,0.785687878,1.153219168,0.743091061,DB0021310047942_,0.296936683,-0.04993046,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,83032,DB00331,10047942,224,24722,157,20595,0.09857524,1.188569789,0.964040492,1.468248199,0.208748569,DB0033110047942_,1.56662477,0.172750726,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,metformin,DB00331
,83033,DB00572,10047942,62,2840,36,2090,0.301892127,1.267350719,0.823807333,1.975671532,0.468243831,DB0057210047942_,0.758766112,0.236928674,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,atropine,DB00572
,83034,DB00788,10047942,97,9259,34,5027,0.027357627,1.548906761,1.036517918,2.365396853,0.078774737,DB0078810047942_,2.541162926,0.437549367,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,naproxen,DB00788
,83035,DB00836,10047942,118,5417,63,4012,0.04019028,1.387166888,1.01022976,1.920051339,0.106064409,DB0083610047942_,2.243708739,0.327263457,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,loperamide,DB00836
,83045,DB00051,10004146,55,25676,33,11387,0.167076148,0.73913673,0.471287369,1.175732847,0.306932943,DB0005110004146_,1.18112598,-0.302272355,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,adalimumab,DB00051
,83064,DB06817,10071404,34,648,41,701,0.721979527,0.897166902,0.544905121,1.468801569,0.836204009,DB0681710071404_,0.178882666,-0.108513367,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,raltegravir,DB06817
,83065,DB00264,10019974,131,29476,85,24807,0.06468027,1.297046227,0.979195874,1.72575879,0.15189144,DB0026410019974_,1.884589224,0.260089546,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,metoprolol,DB00264
,83066,DB00338,10019974,170,33504,76,22196,0.004033627,1.481870263,1.123639778,1.969787894,0.017197712,DB0033810019974_,4.062978925,0.393304981,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,omeprazole,DB00338
,83067,DB00482,10019974,54,8205,12,3059,0.125677419,1.677690709,0.884886023,3.45039003,0.249615884,DB0048210019974_,1.387832006,0.51741827,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,celecoxib,DB00482
,83068,DB00497,10019974,85,19182,54,16321,0.104982389,1.339287498,0.940552722,1.921466472,0.218493376,DB0049710019974_,1.52099958,0.292137755,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,oxycodone,DB00497
,83069,DB00563,10019974,303,46343,74,15274,0.019591328,1.349496682,1.042761249,1.76569371,0.06081583,DB0056310019974_,2.799905155,0.299731695,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,methotrexate,DB00563
,83070,DB00264,10039101,170,29437,85,24807,6.7468856164882e-05,1.685409557,1.290835469,2.214414821,0.000569042,DB0026410039101_,7.4715566,0.522008595,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,83071,DB00281,10039101,42,11416,12,5659,0.110252653,1.734926762,0.895841881,3.62308884,0.226422504,DB0028110039101_,1.485352536,0.5509652,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,83072,DB00338,10039101,183,33491,93,22179,0.041754915,1.303106188,1.009206802,1.692117266,0.10923937,DB0033810039101_,2.214213749,0.26475079,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,83074,DB00497,10039101,70,19197,35,16340,0.010507969,1.702319861,1.118384453,2.633852544,0.037031838,DB0049710039101_,3.295977241,0.531991945,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,83075,DB00996,10039101,181,38772,73,22352,0.010731886,1.429392246,1.082895259,1.903422993,0.037661899,DB0099610039101_,3.279106342,0.357249351,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,83076,DB00999,10039101,129,21301,34,12205,2.65905469006289e-05,2.173897839,1.478856891,3.27508193,0.000254713,DB0099910039101_,8.275373061,0.776521796,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,83077,DB01076,10039101,123,25624,88,25495,0.018918863,1.390676126,1.0485617,1.85079536,0.0591545,DB0107610039101_,2.827602616,0.32979005,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,83078,DB00264,10040742,37,29570,19,24873,0.082069168,1.638022994,0.917887958,3.016288691,0.181803387,DB0026410040742_,1.704829465,0.493490023,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,83080,DB00338,10040742,46,33628,25,22247,0.468227008,1.217245745,0.732206136,2.068159036,0.634775609,DB0033810040742_,0.454483714,0.196590721,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,83083,DB00563,10040742,52,46594,14,15334,0.57019326,1.222355026,0.667303589,2.389112728,0.720856239,DB0056310040742_,0.327315553,0.200779347,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,83084,DB00682,10040742,55,19404,27,16337,0.02584275,1.715032994,1.062960157,2.829254291,0.075345426,DB0068210040742_,2.585672059,0.539432319,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,83085,DB00722,10040742,32,25371,22,26010,0.173201256,1.491159905,0.839710465,2.694342222,0.315102091,DB0072210040742_,1.154858594,0.399554277,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,83087,DB01076,10040742,32,25715,18,25565,0.064846787,1.76737789,0.962292628,3.345099713,0.152194097,DB0107610040742_,1.882598617,0.56949703,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,83088,DB08895,10040742,58,28056,10,6636,0.44037347,1.371839994,0.694704461,3.012502266,0.608725337,DB0889510040742_,0.496388119,0.3161529,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,83089,DB00581,10040047,49,2064,51,2018,0.762583401,0.939358617,0.618341252,1.425790557,0.868521505,DB0058110040047_,0.140962932,-0.062557959,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,lactulose,DB00581
,83101,DB00321,10040108,38,7409,33,2817,0.000747717,0.437856387,0.266788544,0.721979275,0.004323781,DB0032110040108_,5.443625009,-0.825864307,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,83106,DB00321,10053762,207,7240,79,2771,1,1.002862005,0.767236962,1.321644815,1,DB0032110053762_,0,0.002857917,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,amitriptyline,DB00321
,83107,DB01024,10053762,126,2085,130,1990,0.562267593,0.925102711,0.712529522,1.200750725,0.714506209,DB0102410053762_,0.336163592,-0.077850509,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,mycophenolic acid,DB01024
,83138,DB00338,10003285,153,33521,77,22195,0.050415115,1.31563867,0.993522876,1.754377995,0.125792519,DB0033810003285_,2.073121402,0.274322229,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,83139,DB00381,10003285,111,29249,56,22831,0.007774651,1.547193358,1.111726828,2.174382229,0.029104423,DB0038110003285_,3.536865137,0.436442553,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,83140,DB00678,10003285,59,15540,39,10685,0.918082142,1.040188352,0.681994345,1.60240435,0.963671869,DB0067810003285_,0.037004427,0.039401805,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,83154,DB00697,10033371,419,5677,83,1723,0.000351569,1.532015697,1.199981657,1.975313808,0.002301901,DB0069710033371_,6.074020054,0.426584318,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,83156,DB00697,10037377,40,6056,15,1791,0.422510387,0.788664679,0.425077454,1.54064273,0.591524426,DB0069710037377_,0.525052302,-0.237414043,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tizanidine,DB00697
,83167,DB00404,10002034,253,19639,95,9767,0.021803699,1.324480392,1.040810848,1.697109895,0.06617137,DB0040410002034_,2.715507387,0.281020226,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,alprazolam,DB00404
,83169,DB00343,10007554,72,8664,44,5051,0.846829178,0.953995097,0.645597965,1.423832039,0.923069792,DB0034310007554_,0.080050434,-0.047096747,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,diltiazem,DB00343
,83171,DB01076,10007554,83,25664,139,25444,0.000153855,0.592013353,0.445268894,0.783003126,0.001152489,DB0107610007554_,6.765831634,-0.524226089,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,83172,DB11089,10007554,45,10130,51,8356,0.124060888,0.727851121,0.475906065,1.109877498,0.247172018,DB1108910007554_,1.397670754,-0.317658756,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,docusate,DB11089
,83174,DB00264,10028735,191,29416,65,24827,2.26327704301493e-11,2.479933171,1.861413669,3.340924852,8.16052634782544e-10,DB0026410028735_,20.92654226,0.908231613,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,83175,DB00404,10028735,124,19768,29,9833,0.00013388,2.126852269,1.409074983,3.309132736,0.001022235,DB0040410028735_,6.885763828,0.754643079,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,83177,DB01076,10028735,149,25598,79,25504,4.04924963540715e-06,1.879116238,1.420288415,2.502261496,4.9105946359478e-05,DB0107610028735_,9.921530423,0.63080158,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,83178,DB01592,10028735,56,6220,13,3054,0.013884629,2.114917113,1.140142246,4.222424313,0.046246909,DB0159210028735_,3.07376066,0.749015622,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iron,DB01592
,83184,DB00343,10039101,57,8679,14,5081,0.002788296,2.383427956,1.309622159,4.636283477,0.012731757,DB0034310039101_,4.363655891,0.868539769,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,83186,DB01592,10039101,53,6223,17,3050,0.159226957,1.527948738,0.869074652,2.819912724,0.296449963,DB0159210039101_,1.215876834,0.423926142,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iron,DB01592
,83187,DB09140,10039101,85,3656,21,1777,0.004509039,1.96713632,1.204067405,3.351623609,0.018802945,DB0914010039101_,3.973741771,0.676578841,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,83188,DB11089,10039101,40,10135,37,8370,0.647335553,0.892818226,0.555980011,1.437125728,0.7825426,DB1108910039101_,0.245206917,-0.113372273,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,83190,DB00343,10047924,41,8695,22,5073,0.794869169,1.087321515,0.631896283,1.918942865,0.88886159,DB0034310047924_,0.117813747,0.083717346,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,83192,DB01076,10047924,86,25661,50,25533,0.002542828,1.711392481,1.193468561,2.477104907,0.011814095,DB0107610047924_,4.438462004,0.537307355,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,83194,DB09140,10047924,61,3680,24,1774,0.483717038,1.225177858,0.749770002,2.062179602,0.647955274,DB0914010047924_,0.433933607,0.203086023,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,83195,DB11089,10047924,34,10141,22,8385,0.420774879,1.277828025,0.725388903,2.295315512,0.589760189,DB1108910047924_,0.528039285,0.245161781,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,83197,DB00316,10064780,41,65433,28,36925,0.453014049,0.826333908,0.498703703,1.387706043,0.620601151,DB0031610064780_,0.477066673,-0.19075634,NA,10064780,Breath sounds abnormal,10022891,Investigations,Inv,acetaminophen,DB00316
,83211,DB00331,10022081,77,24869,48,20704,0.126273929,1.335494423,0.918968114,1.958054173,0.250489433,DB0033110022081_,1.384338543,0.289301577,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,83212,DB01267,10022081,51,2801,22,3693,7.00723638463823e-06,3.055920421,1.815306619,5.304890179,7.94929686535243e-05,DB0126710022081_,9.439841985,1.117080831,female,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,83222,DB00338,10041101,81,33593,53,22219,1,1.010845794,0.705960289,1.458021369,1,DB0033810041101_,0,0.0107874,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,83227,DB00338,10046274,35,33639,60,22212,4.75947149270034e-06,0.38518302,0.246251952,0.594248573,5.66507054728636e-05,DB0033810046274_,9.778606117,-0.954036681,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,83229,DB14726,10046274,39,1978,82,2766,0.039691616,0.665138446,0.440175907,0.990056614,0.105040611,DB1472610046274_,2.253408235,-0.407760071,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,dabigatran,DB14726
,83231,DB00213,10061309,45,18850,31,13390,1,1.031147516,0.637902541,1.686565233,1,DB0021310061309_,0,0.030672275,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pantoprazole,DB00213
,83232,DB00338,10061309,88,33586,47,22225,0.253105478,1.238969933,0.859567575,1.805884743,0.413504724,DB0033810061309_,0.883086341,0.214280335,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,omeprazole,DB00338
,83233,DB00497,10061309,93,19174,80,16295,0.939214482,0.987947876,0.72424123,1.350274059,0.978804305,DB0049710061309_,0.021423549,-0.01212534,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,oxycodone,DB00497
,83245,DB00203,10000059,325,13553,153,8785,0.001078097,1.376867501,1.130455195,1.682957221,0.005862785,DB0020310000059_,5.139130571,0.319810992,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,83249,DB00203,10028411,405,13473,157,8781,1.878785076569e-08,1.681221679,1.392022696,2.038595842,3.9569958474132e-07,DB0020310028411_,14.74261054,0.519520719,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,83250,DB00559,10028411,99,9560,21,3285,0.045341994,1.619795773,1.00199477,2.736829748,0.116243391,DB0055910028411_,2.152069091,0.482300075,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,bosentan,DB00559
,83254,DB00203,10052268,165,13713,33,8905,6.9670628446541e-12,3.246757922,2.221045715,4.877652363,2.74243261852311e-10,DB0020310052268_,22.01700559,1.177656936,female,10052268,Catheter site pain,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,83255,DB00374,10052268,213,17503,48,5676,0.024428078,1.438975253,1.046181435,2.014476718,0.072242577,DB0037410052268_,2.627725697,0.36393123,NA,10052268,Catheter site pain,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,83256,DB00559,10052268,76,9583,15,3291,0.052841013,1.740025404,0.989759957,3.264947857,0.130409468,DB0055910052268_,2.037076026,0.553899713,NA,10052268,Catheter site pain,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,83258,DB06228,10038153,41,15871,32,16044,0.292842031,1.295201916,0.795461859,2.126004442,0.458421343,DB0622810038153_,0.779966554,0.258666603,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,rivaroxaban,DB06228
,83259,DB06228,10049414,119,15793,117,15959,0.844854803,1.027789645,0.788761791,1.339403691,0.921659279,DB0622810049414_,0.081579669,0.027410521,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,83289,DB00331,10013774,48,24898,18,20734,0.002866902,2.220600606,1.26777099,4.058031477,0.013030697,DB0033110013774_,4.340447397,0.797777703,NA,10013774,Dry eye,10015919,Eye disorders,Eye,metformin,DB00331
,83292,DB00736,10013774,44,10547,10,5543,0.01411612,2.312326494,1.1454167,5.157358473,0.046905026,DB0073610013774_,3.059630443,0.838254158,NA,10013774,Dry eye,10015919,Eye disorders,Eye,esomeprazole,DB00736
,83296,DB13961,10013774,70,9387,19,6395,0.000193978,2.509764774,1.492535938,4.418574128,0.001404026,DB1396110013774_,6.568411263,0.920189033,NA,10013774,Dry eye,10015919,Eye disorders,Eye,fish oil,DB13961
,83300,DB00471,10013781,73,14116,15,5450,0.023251435,1.878926784,1.066895284,3.530298322,0.069463309,DB0047110013781_,2.666956601,0.630700754,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,83302,DB00736,10013781,58,10533,25,5528,0.487169305,1.217551553,0.748741917,2.0338317,0.651053471,DB0073610013781_,0.429163504,0.196841918,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,83305,DB13961,10013781,74,9383,35,6379,0.078560138,1.43735722,0.947853092,2.217565836,0.175920364,DB1396110013781_,1.737723864,0.362806163,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,83309,DB00331,10015946,38,24908,22,20730,0.19520974,1.437530667,0.828552619,2.55259823,0.343296959,DB0033110015946_,1.069159436,0.362926827,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,metformin,DB00331
,83329,DB00627,10047895,23,1306,35,1564,0.425135957,0.787025668,0.44156556,1.3779904,0.593893422,DB0062710047895_,0.5210554,-0.239494416,NA,10047895,Weight decreased,10022891,Investigations,Inv,niacin,DB00627
,83330,DB06292,10047895,47,1310,55,1178,0.224725463,0.768520643,0.505093291,1.165346528,0.37942631,DB0629210047895_,0.969094878,-0.263287855,NA,10047895,Weight decreased,10022891,Investigations,Inv,dapagliflozin,DB06292
,83336,DB00433,10037377,102,7554,92,5928,0.344377005,0.870059302,0.648492476,1.168646904,0.513716953,DB0043310037377_,0.66608284,-0.139193906,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,83338,DB01060,10037377,46,8541,36,5045,0.209163462,0.754791466,0.476683803,1.203530884,0.360196652,DB0106010037377_,1.02110514,-0.281313773,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amoxicillin,DB01060
,83353,DB00904,10047302,71,22998,65,14391,0.02746165,0.683539207,0.480963982,0.972734063,0.079022328,DB0090410047302_,2.538024831,-0.380471262,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,ondansetron,DB00904
,83368,DB00060,10020751,92,9416,29,2436,0.365826261,0.820745089,0.534065692,1.295903235,0.535412638,DB0006010020751_,0.624717544,-0.197542706,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,interferon beta-1a,DB00060
,83369,DB01136,10008190,120,9764,146,10969,0.536891525,0.923327924,0.717981063,1.185637348,0.693133288,DB0113610008190_,0.366532964,-0.079770827,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,83373,DB00425,10069326,42,12653,27,7457,0.710122715,0.91676642,0.551641179,1.547586996,0.827129206,DB0042510069326_,0.189794361,-0.086902561,NA,10069326,Product substitution issue,10077536,Product issues,Prod,zolpidem,DB00425
,83378,DB00874,10003658,42,3293,35,1941,0.153687162,0.707389103,0.439211213,1.145538038,0.289063831,DB0087410003658_,1.241107746,-0.346174407,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,guaifenesin,DB00874
,83383,DB00820,10010305,107,11808,44,5772,0.384067239,1.188695121,0.82816151,1.731879544,0.554118471,DB0082010010305_,0.590376768,0.172856168,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,tadalafil,DB00820
,83385,DB01377,10010305,70,3726,40,2630,0.328907346,1.235198812,0.823062865,1.876260306,0.497515658,DB0137710010305_,0.69812825,0.211231938,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,magnesium oxide,DB01377
,83387,DB00350,10013968,14,526,36,425,0.000208223,0.314566429,0.154605353,0.606956026,0.001489963,DB0035010013968_,6.509004056,-1.156560004,male,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,minoxidil,DB00350
,83389,DB04861,10013968,107,1858,60,1327,0.147578744,1.273581576,0.912165565,1.79206748,0.280627018,DB0486110013968_,1.270728828,0.24183307,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nebivolol,DB04861
,83392,DB00737,10016173,151,2650,36,896,0.068577934,1.418027322,0.971693928,2.117607225,0.158746894,DB0073710016173_,1.840444206,0.349266696,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,meclizine,DB00737
,83394,DB01377,10016173,158,3638,88,2582,0.074903835,1.274241555,0.970657639,1.681614228,0.169691644,DB0137710016173_,1.773772348,0.242351143,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium oxide,DB01377
,83395,DB04861,10016173,52,1913,27,1360,0.204688154,1.369063858,0.839356191,2.279422508,0.35468736,DB0486110016173_,1.036518554,0.314127191,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,nebivolol,DB04861
,83400,DB00820,10021015,38,11877,18,5798,1,1.030612562,0.573352997,1.920115222,1,DB0082010021015_,0,0.030153346,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,tadalafil,DB00820
,83403,DB01377,10021015,44,3752,20,2650,0.125172993,1.553734871,0.894280907,2.789555488,0.248868735,DB0137710021015_,1.390829691,0.440661627,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,magnesium oxide,DB01377
,83407,DB00874,10021097,42,3293,38,1938,0.062042406,0.6505525,0.407788576,1.040701876,0.147262474,DB0087410021097_,1.915538747,-0.429933277,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,guaifenesin,DB00874
,83408,DB04861,10021097,34,1931,42,1345,0.017883504,0.563971628,0.345996843,0.913291121,0.05660369,DB0486110021097_,2.871681095,-0.572751333,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,nebivolol,DB04861
,83409,DB00193,10021143,82,19238,55,8647,0.02594295,0.670132902,0.470017365,0.961907918,0.075570066,DB0019310021143_,2.58269503,-0.400279226,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,83410,DB00254,10021143,41,5894,26,3362,0.702808684,0.899506466,0.536139958,1.534534944,0.821701075,DB0025410021143_,0.196378605,-0.105909037,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxycycline,DB00254
,83415,DB00874,10021143,41,3294,31,1945,0.326572127,0.780992382,0.476187154,1.29262832,0.495035038,DB0087410021143_,0.703126735,-0.247189883,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,guaifenesin,DB00874
,83416,DB01377,10021143,61,3735,46,2624,0.766657705,0.9316445,0.622791183,1.402037241,0.871571202,DB0137710021143_,0.137457717,-0.070803975,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium oxide,DB01377
,83426,DB00695,10025282,43,28006,8,20520,8.67298876778325e-05,3.938137602,1.829770351,9.702567804,0.000706444,DB0069510025282_,7.255266487,1.370707922,female,10025282,Lymphoedema,10047065,Vascular disorders,Vasc,furosemide,DB00695
,83436,DB04861,10028813,147,1818,64,1323,0.000677883,1.67124145,1.226603934,2.29789376,0.003988394,DB0486110028813_,5.524366579,0.513566733,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,nebivolol,DB04861
,83437,DB00047,10030124,109,9176,104,8414,0.782941059,0.961030411,0.726560312,1.271778063,0.881806742,DB0004710030124_,0.12578236,-0.039749225,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,83445,DB00316,10039163,87,65387,30,36923,0.020426929,1.637575842,1.070007006,2.570163222,0.062841618,DB0031610039163_,2.767137721,0.493217003,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,83455,DB00737,10047700,119,2682,27,905,0.078508602,1.487011277,0.965100489,2.366245565,0.175864889,DB0073710047700_,1.738039255,0.396768251,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,meclizine,DB00737
,83456,DB04861,10047700,57,1908,22,1365,0.014820444,1.853232278,1.109046238,3.200179077,0.048850133,DB0486110047700_,3.018998184,0.616931292,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,nebivolol,DB04861
,83464,DB00695,10058046,38,28011,23,20505,0.518178576,1.209439408,0.702060253,2.127239346,0.677510079,DB0069510058046_,0.389330849,0.190156953,NA,10058046,Post procedural complication,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,83472,DB06228,10017853,27,15885,44,16032,0.056771035,0.619327629,0.368596973,1.023152714,0.137367823,DB0622810017853_,1.985093112,-0.479120859,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,83476,DB09072,10067482,44,6427,13,2522,0.460128036,1.328077013,0.701113448,2.692499051,0.627566776,DB0907210067482_,0.465905198,0.283732041,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,83479,DB00658,10003549,32,1271,33,1363,0.900556124,1.039886223,0.61508008,1.756138595,0.956698706,DB0065810003549_,0.044266769,0.039111306,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sevelamer,DB00658
,83484,DB00927,10014625,33,7464,24,4992,0.787194512,0.919621186,0.526564412,1.628225077,0.884664062,DB0092710014625_,0.122547297,-0.083793448,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,83487,DB01136,10017577,114,9770,101,11014,0.085908827,1.27241042,0.963443981,1.682493792,0.188199652,DB0113610017577_,1.670251902,0.24091307,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,83495,DB00658,10038435,46,1257,41,1355,0.385802029,1.209334396,0.770585701,1.903427778,0.55595002,DB0065810038435_,0.587076882,0.190070122,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,sevelamer,DB00658
,83496,DB00658,10040047,26,1277,56,1340,0.002341636,0.487317438,0.291804459,0.794722265,0.011060527,DB0065810040047_,4.504372679,-0.718839545,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,sevelamer,DB00658
,83500,DB00559,10038428,62,9597,22,3284,0.900143763,0.964355036,0.583422962,1.650337264,0.956646281,DB0055910038428_,0.044321568,-0.036295758,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,bosentan,DB00559
,83501,DB00203,10005724,137,13741,33,8905,3.53144690438871e-08,2.690305235,1.826591809,4.067197791,7.02618644256e-07,DB0020310005724_,14.16845156,0.989654657,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,sildenafil,DB00203
,83502,DB00524,10005724,38,1539,19,1325,0.060014934,1.72158408,0.962744407,3.177902859,0.143486489,DB0052410005724_,1.941514404,0.543244844,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,metolazone,DB00524
,83504,DB00203,10021015,62,13816,35,8903,0.602529897,1.141530191,0.741781722,1.781982968,0.746418058,DB0020310021015_,0.292469437,0.132369635,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,sildenafil,DB00203
,83505,DB00374,10021015,76,17640,14,5710,0.04951669,1.757098609,0.984772305,3.368158901,0.124078842,DB0037410021015_,2.08683809,0.563663931,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,treprostinil,DB00374
,83506,DB06403,10021015,46,21425,10,6651,0.348386104,1.427948793,0.710317468,3.175485527,0.517963107,DB0640310021015_,0.657851261,0.356239004,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,ambrisentan,DB06403
,83507,DB00203,10021036,53,13825,27,8911,0.359434658,1.265213101,0.781097692,2.093772928,0.529151754,DB0020310021036_,0.636480019,0.235240567,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,sildenafil,DB00203
,83508,DB00374,10021036,40,17676,13,5711,1,0.9941339,0.520453136,2.027320662,1,DB0037410021036_,0,-0.005883373,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,treprostinil,DB00374
,83509,DB00524,10021036,23,1554,34,1310,0.043639501,0.570372242,0.319041916,1.0026336,0.112893144,DB0052410021036_,2.181313539,-0.561466076,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,metolazone,DB00524
,83520,DB00502,10013709,106,1288,146,1726,0.894555056,0.972926905,0.742396184,1.271789109,0.955948677,DB0050210013709_,0.045051053,-0.027446323,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,haloperidol,DB00502
,83529,DB00363,10040047,32,4596,72,6816,0.055905644,0.659147166,0.419742143,1.014694838,0.135921166,DB0036310040047_,1.995680226,-0.416808452,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,clozapine,DB00363
,83534,DB01267,10039897,23,2829,53,3662,0.01997428,0.561792807,0.327752415,0.935234862,0.061698567,DB0126710039897_,2.785494582,-0.576622168,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,paliperidone,DB01267
,83543,DB00009,10055798,63,1288,80,1471,0.548675114,0.899434965,0.630432094,1.278586812,0.703114124,DB0000910055798_,0.352236062,-0.10598853,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,alteplase,DB00009
,83547,DB06228,10037400,113,15799,48,16028,1.92976955006688e-07,2.388338777,1.688200334,3.423883784,3.28629689818645e-06,DB0622810037400_,12.62574919,0.870598052,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,83572,DB00060,10003285,54,9454,11,2454,0.540317815,1.274237893,0.65750092,2.706865837,0.695898952,DB0006010003285_,0.362550813,0.242348269,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,83574,DB01164,10019211,46,6478,22,7914,0.000208024,2.554255049,1.503806271,4.463395258,0.00148888,DB0116410019211_,6.509730984,0.937760615,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,calcium chloride,DB01164
,83587,DB00921,10016322,119,5726,113,4790,0.351323802,0.880964424,0.673196646,1.153374929,0.521034002,DB0092110016322_,0.651939976,-0.126738035,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,83590,DB08931,10010264,297,6280,110,2336,1,1.004331184,0.799967392,1.268215778,1,DB0893110010264_,0,0.004321832,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,83591,DB00820,10051301,40,11875,14,5802,0.312418059,1.395960467,0.742790103,2.780343023,0.47991634,DB0082010051301_,0.734143481,0.333582685,NA,10051301,Exercise tolerance decreased,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,83593,DB06403,10051301,48,21423,19,6642,0.387709364,0.783267841,0.451530184,1.412069499,0.557709234,DB0640310051301_,0.583917538,-0.244280572,NA,10051301,Exercise tolerance decreased,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,83595,DB00243,10003549,37,1217,54,1572,0.592978889,0.885111638,0.562314691,1.379881684,0.739149718,DB0024310003549_,0.302254783,-0.122041497,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ranolazine,DB00243
,83596,DB01065,10003549,142,4189,95,2956,0.7375708,1.054773689,0.804091573,1.388609199,0.848772019,DB0106510003549_,0.163964658,0.053326231,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,83602,DB01065,10047513,48,4283,14,3037,0.0026279,2.430858265,1.315371246,4.783219156,0.012136405,DB0106510047513_,4.411545645,0.88824439,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,melatonin,DB01065
,83606,DB00921,10033557,31,5814,19,4884,0.320154606,1.370551858,0.749087051,2.571217465,0.488379306,DB0092110033557_,0.716662908,0.315213475,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,buprenorphine,DB00921
,83608,DB00028,10007882,74,13384,31,5584,1,0.99593178,0.645786637,1.569544631,1,DB0002810007882_,0,-0.004076518,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,83611,DB00028,10022000,164,13294,73,5542,0.667039642,0.936556757,0.705286812,1.253847073,0.797649652,DB0002810022000_,0.226085811,-0.065545154,NA,10022000,Influenza,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,83612,DB00028,10061623,46,13412,17,5598,0.782098139,1.129390623,0.634596113,2.103262497,0.881329429,DB0002810061623_,0.126323797,0.121678215,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,83616,DB00404,10013990,49,19843,22,9840,0.800931498,1.104481137,0.654894295,1.919441314,0.892356919,DB0040410013990_,0.113889093,0.099375665,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,alprazolam,DB00404
,83618,DB00563,10013990,43,46603,16,15332,0.652518308,0.884152023,0.487839269,1.682129286,0.786745429,DB0056310013990_,0.239850553,-0.123126259,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,methotrexate,DB00563
,83625,DB00215,10033661,21,11082,31,5245,6.9441778576224e-05,0.320640427,0.174922787,0.576791492,0.000583119,DB0021510033661_,7.447119731,-1.137434948,male,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,citalopram,DB00215
,83626,DB05259,10065154,200,11070,46,2682,0.807766513,1.053394239,0.758886015,1.48908128,0.896255547,DB0525910065154_,0.109529698,0.052017559,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,glatiramer,DB05259
,83628,DB00108,10012378,130,10064,40,3255,0.857516928,1.051114659,0.730567382,1.54169831,0.931725294,DB0010810012378_,0.070717257,0.049851181,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,natalizumab,DB00108
,83629,DB00060,10027599,97,9411,10,2455,0.002509378,2.530292797,1.315913579,5.451424709,0.011693822,DB0006010027599_,4.448694576,0.928335026,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,83630,DB00108,10027599,92,10102,15,3280,0.01240615,1.991220544,1.144722989,3.707039198,0.042270731,DB0010810027599_,3.163660381,0.688747789,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,83631,DB05259,10027599,79,11191,20,2708,0.800349973,0.95581956,0.57813799,1.651764441,0.892049316,DB0525910027599_,0.114233861,-0.045186128,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,83637,DB00480,10003011,31,67397,37,67625,0.544551753,0.84067429,0.504305548,1.392742764,0.699501176,DB0048010003011_,0.357387803,-0.173550984,NA,10003011,Appendicitis,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,83645,DB00480,10030095,127,67301,118,67544,0.56529567,1.080127084,0.833856831,1.400108711,0.716865154,DB0048010030095_,0.332867525,0.077078705,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,83647,DB00343,10035528,65,8671,46,5049,0.323981621,0.822816469,0.554444965,1.229793609,0.492402609,DB0034310035528_,0.708458587,-0.195022105,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,diltiazem,DB00343
,83649,DB01137,10035528,89,7683,97,5496,0.004427721,0.656382985,0.485598426,0.886301119,0.018533283,DB0113710035528_,3.988187078,-0.421010842,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,levofloxacin,DB01137
,83661,DB00169,10062352,92,38599,28,18147,0.049465721,1.544740387,1.00194447,2.451178319,0.124012254,DB0016910062352_,2.087374892,0.434855862,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,83666,DB00904,10062352,59,23010,17,14439,0.003117742,2.177781291,1.251741186,3.987311105,0.013964359,DB0090410062352_,4.271246982,0.778306602,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,ondansetron,DB00904
,83670,DB01373,10062352,44,22676,11,7370,0.530988761,1.300030881,0.660257928,2.792738926,0.687911656,DB0137310062352_,0.374094856,0.262388019,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,calcium,DB01373
,83675,DB00668,10056871,65,10026,52,4251,0.00106718,0.529995327,0.361734014,0.780017279,0.005811232,DB0066810056871_,5.147962608,-0.63488709,NA,10056871,Device failure,10077536,Product issues,Prod,epinephrine,DB00668
,83677,DB08868,10001760,177,9025,12,2499,1.64534852193773e-08,4.083973825,2.275366307,8.0678968,3.51156665676541e-07,DB0886810001760_,14.86203337,1.407070491,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,fingolimod,DB08868
,83687,DB06643,10061623,260,52161,17,7498,0.000702703,2.198468908,1.345712304,3.834584263,0.00410548,DB0664310061623_,5.495432727,0.787761167,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,83689,DB00321,10025482,218,7229,55,2795,0.004830423,1.532474994,1.131380795,2.10617197,0.019916495,DB0032110025482_,3.916206973,0.426884072,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,83692,DB00813,10006451,45,10527,22,10146,0.009680165,1.971352531,1.158341455,3.450222201,0.03467709,DB0081310006451_,3.36167605,0.678719871,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,fentanyl,DB00813
,83693,DB08910,10006451,224,16520,119,17369,8.91792000122264e-10,1.979038315,1.57581283,2.495711941,2.50168118710925e-08,DB0891010006451_,17.50371776,0.682611027,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,83694,DB08910,10012378,85,16659,68,17420,0.105247242,1.307086362,0.938302494,1.826703502,0.218957914,DB0891010012378_,1.518875741,0.267800509,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,pomalidomide,DB08910
,83695,DB00813,10042458,40,10532,16,10152,0.002884884,2.409529684,1.318679204,4.612004201,0.013092054,DB0081310042458_,4.335749774,0.879431577,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,fentanyl,DB00813
,83698,DB00641,10048294,50,14074,62,12413,0.087238463,0.711289298,0.479640085,1.05016128,0.190501204,DB0064110048294_,1.658096765,-0.340676043,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,83700,DB05259,10050584,116,11154,22,2706,0.331459771,1.279158157,0.804144888,2.12410415,0.500253794,DB0525910050584_,0.692639722,0.246202172,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,glatiramer,DB05259
,83705,DB00813,10001497,59,10513,96,10072,0.001577273,0.588822039,0.417878356,0.823776403,0.008007461,DB0081310001497_,4.827381547,-0.529631282,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,fentanyl,DB00813
,83709,DB00264,10033295,138,29469,136,24756,0.201691962,0.852427454,0.667357486,1.088995804,0.351111796,DB0026410033295_,1.046650599,-0.159667172,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,83710,DB01212,10011906,58,1961,55,1886,1,1.014211366,0.685134523,1.502896235,1,DB0121210011906_,0,0.014111331,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ceftriaxone,DB01212
,83711,DB01212,10021097,71,1948,69,1872,1,0.988841985,0.695360808,1.406809383,1,DB0121210021097_,0,-0.011220732,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ceftriaxone,DB01212
,83734,DB01611,10053425,120,11793,7,2354,0.000270117,3.42170384,1.60765038,8.704437768,0.001851981,DB0161110053425_,6.291499608,1.230138626,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,83740,DB05259,10030942,46,11224,7,2721,0.299093675,1.5930314,0.71333509,4.187000794,0.465064168,DB0525910030942_,0.765579886,0.465638742,NA,10030942,Optic neuritis,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,83741,DB00331,10029366,38,24908,36,20716,0.64057857,0.87790991,0.541465508,1.42581324,0.777503126,DB0033110029366_,0.251667614,-0.130211299,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,metformin,DB00331
,83742,DB00958,10047942,202,4392,35,2550,1.86510970085677e-13,3.3504323,2.322602358,4.961523996,9.25862294372431e-12,DB0095810047942_,25.40546579,1.209089382,female,10047942,White blood cell count decreased,10022891,Investigations,Inv,carboplatin,DB00958
,83743,DB01229,10047942,151,5590,34,2675,3.05862067419348e-05,2.125086824,1.452130108,3.190409952,0.000288674,DB0122910047942_,8.15021085,0.75381266,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,paclitaxel,DB01229
,83748,DB00575,10010264,95,5149,57,3772,0.247199815,1.220922112,0.867552793,1.731516401,0.406369626,DB0057510010264_,0.900492124,0.199606403,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,83749,DB01224,10010264,140,7968,109,5808,0.605303587,0.936230442,0.721889095,1.216781215,0.748460768,DB0122410010264_,0.28973649,-0.065893634,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,83754,DB00973,10046571,84,3767,28,2993,3.18817697125951e-05,2.383268673,1.532856602,3.808725038,0.000299451,DB0097310046571_,8.113561319,0.868472937,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ezetimibe,DB00973
,83764,DB00727,10002855,82,3761,39,4134,1.29132885957579e-05,2.31086465,1.555583588,3.484792309,0.000135961,DB0072710002855_,8.90314497,0.837621762,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,nitroglycerin,DB00727
,83766,DB00175,10003553,42,8089,9,6097,0.000177677,3.517140343,1.685960314,8.226295315,0.001304224,DB0017510003553_,6.642147275,1.257648257,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,83767,DB00193,10003553,116,19204,9,8693,1.56555640885107e-10,5.834409936,2.967316046,13.08457398,4.94663961397642e-09,DB0019310003553_,19.12455736,1.763773136,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,83773,DB00175,10003988,181,7950,89,6017,0.000967098,1.539175316,1.184937513,2.011432196,0.005359515,DB0017510003988_,5.228881763,0.431246764,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,83774,DB00471,10003988,285,13904,67,5398,0.00014852,1.651433623,1.25896824,2.192612748,0.001116661,DB0047110003988_,6.797412009,0.501643773,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,83777,DB00175,10008479,126,8005,83,6023,0.360909664,1.142167871,0.857120347,1.528826302,0.530818493,DB0017510008479_,0.633335138,0.132928098,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,83779,DB01377,10008479,71,3725,40,2630,0.285179659,1.253178095,0.83601688,1.901685062,0.449774832,DB0137710008479_,0.799008195,0.225682801,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,83782,DB00727,10008531,40,3803,24,4149,0.023186314,1.81815118,1.067345977,3.15968666,0.069323319,DB0072710008531_,2.668973934,0.59782015,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,83783,DB00175,10009033,51,8080,45,6061,0.469208434,0.850152825,0.557309626,1.300761781,0.635516125,DB0017510009033_,0.453317815,-0.162339152,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,83784,DB00471,10009033,144,14045,66,5399,0.245636388,0.838737922,0.621399598,1.142157559,0.404507876,DB0047110009033_,0.905084071,-0.175856991,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,83786,DB00727,10009033,53,3790,44,4129,0.185768113,1.312236769,0.860945437,2.008877371,0.331157331,DB0072710009033_,1.105161697,0.271733139,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nitroglycerin,DB00727
,83787,DB01377,10009033,39,3757,27,2643,1,1.016145897,0.604686302,1.730820288,1,DB0137710009033_,0,0.016016938,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium oxide,DB01377
,83788,DB06643,10009033,85,52336,17,7498,0.228861281,0.716339691,0.421861236,1.287368694,0.384532011,DB0664310009033_,0.95572824,-0.333600796,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,denosumab,DB06643
,83791,DB00612,10013968,63,1077,30,610,0.505857871,1.189344706,0.748897431,1.925723402,0.666698346,DB0061210013968_,0.405417591,0.173402488,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bisoprolol,DB00612
,83792,DB00175,10017885,54,8077,32,6074,0.325681127,1.268998405,0.803660417,2.033527175,0.494156978,DB0017510017885_,0.704902043,0.238227932,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,83794,DB00727,10017885,32,3811,27,4146,0.3612615,1.289321146,0.746771114,2.241481931,0.531142103,DB0072710017885_,0.63272568,0.254115836,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,nitroglycerin,DB00727
,83797,DB00175,10020937,99,8032,49,6057,0.015498552,1.523561511,1.069446215,2.195432641,0.050568451,DB0017510020937_,2.984427398,0.421050693,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,83798,DB00193,10020937,267,19053,66,8636,4.09107525669455e-06,1.833615439,1.393959765,2.441766384,4.95205678665514e-05,DB0019310020937_,9.913122462,0.606289668,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,83799,DB00471,10020937,152,14037,44,5421,0.108666179,1.334073987,0.946664586,1.91397918,0.224031571,DB0047110020937_,1.495968297,0.288237408,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,83801,DB01377,10020937,44,3752,12,2658,0.002423981,2.597187164,1.345207633,5.412531548,0.011379592,DB0137710020937_,4.475933683,0.954428999,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,magnesium oxide,DB01377
,83803,DB00612,10033371,44,1096,12,628,0.023055724,2.100197587,1.080386668,4.402125848,0.069038471,DB0061210033371_,2.673091375,0.742031429,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,bisoprolol,DB00612
,83815,DB00471,10037844,431,13758,151,5314,0.324203469,1.102462299,0.911269507,1.33964926,0.492640084,DB0047110037844_,0.707976424,0.097546132,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,83816,DB00612,10037844,35,1105,18,622,0.884617279,1.094476996,0.597454277,2.071171399,0.951939928,DB0061210037844_,0.049253347,0.09027662,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,bisoprolol,DB00612
,83817,DB01377,10037844,90,3706,54,2616,0.392190536,1.176421257,0.827057262,1.687026818,0.562059225,DB0137710037844_,0.576148052,0.162476997,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,magnesium oxide,DB01377
,83819,DB00175,10038695,51,8080,66,6040,0.00351902,0.577667173,0.392166098,0.846665526,0.01539059,DB0017510038695_,4.173998966,-0.548757401,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,83820,DB00193,10038695,118,19202,60,8642,0.464655867,0.885123439,0.642621505,1.230116229,0.631677241,DB0019310038695_,0.459376709,-0.122028164,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,83822,DB01377,10038695,58,3738,47,2623,0.485127359,0.865964832,0.577239693,1.305035107,0.64924888,DB0137710038695_,0.431939153,-0.14391098,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium oxide,DB01377
,83825,DB00193,10040844,47,19273,24,8678,0.609199027,0.881784732,0.528047687,1.508703621,0.751703898,DB0019310040844_,0.285412786,-0.12580732,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,83826,DB00471,10040844,44,14145,19,5446,0.673768639,0.891621569,0.509312728,1.618512533,0.802138219,DB0047110040844_,0.220474343,-0.114713486,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,83827,DB00588,10040844,40,16484,23,8445,0.689854855,0.890990968,0.520288747,1.560017486,0.812952183,DB0058810040844_,0.207082987,-0.115420988,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,83863,DB01012,10062355,74,10558,68,8617,0.498915222,0.888178812,0.629478407,1.254847289,0.660807461,DB0101210062355_,0.414292765,-0.118582191,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,83864,DB00136,10003549,64,2028,53,1629,0.924790506,0.969964192,0.659311909,1.432126183,0.967602836,DB0013610003549_,0.03293357,-0.030496123,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,calcitriol,DB00136
,83865,DB00471,10003549,335,13854,136,5329,0.602858927,0.947493363,0.771991754,1.168127386,0.746632124,DB0047110003549_,0.292182686,-0.053935347,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,83867,DB01394,10003549,56,1384,46,1957,0.007857039,1.721090741,1.136967822,2.616619295,0.029352229,DB0139410003549_,3.528386805,0.542958241,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,colchicine,DB01394
,83868,DB00404,10005483,53,19839,42,9820,0.028399616,0.624619511,0.408484816,0.960560021,0.08116161,DB0040410005483_,2.511312925,-0.470612597,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,alprazolam,DB00404
,83879,DB00136,10012735,107,1985,90,1592,0.768625167,0.953492438,0.707851999,1.286797537,0.873150591,DB0013610012735_,0.13564724,-0.047623785,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,calcitriol,DB00136
,83881,DB00136,10025482,58,2034,38,1644,0.349960023,1.233590661,0.801006278,1.919308802,0.5195831,DB0013610025482_,0.65472852,0.209929154,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,calcitriol,DB00136
,83882,DB00343,10025482,366,8370,81,5014,2.23102684862208e-18,2.706602658,2.1165413,3.496122123,1.98788273613666e-16,DB0034310025482_,36.15429137,0.995694217,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,83883,DB00715,10025482,144,4699,45,2242,0.01415636,1.526709192,1.080959607,2.1925121,0.047020903,DB0071510025482_,3.057163036,0.423114564,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,83885,DB01394,10025482,59,1381,37,1966,9.19438021686581e-05,2.269544152,1.470335967,3.542896629,0.000742752,DB0139410025482_,7.205148449,0.819578997,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,colchicine,DB01394
,83909,DB00051,10015688,42,25689,10,11410,0.096613838,1.865440194,0.920624503,4.171078551,0.205706354,DB0005110015688_,1.581305591,0.623497054,NA,10015688,Exostosis,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,83913,DB00563,10015688,44,46602,10,15338,0.34524597,1.448124521,0.717837948,3.228075733,0.514705002,DB0056310015688_,0.664161354,0.370269285,NA,10015688,Exostosis,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,83916,DB00316,10022067,75,65399,29,36924,0.083331705,1.460156143,0.939420386,2.326072075,0.184015584,DB0031610022067_,1.692734828,0.378543377,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,83920,DB00490,10022086,59,4011,16,1560,0.243314985,1.434037948,0.811416137,2.678788043,0.401653858,DB0049010022086_,0.912164612,0.360494205,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,83921,DB00697,10022086,75,6021,12,1794,0.052927995,1.862040349,1.002810558,3.772220098,0.130532216,DB0069710022086_,2.036135215,0.621672848,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,83930,DB00158,10047461,66,16749,14,8090,0.003818404,2.27700156,1.265037055,4.393070196,0.01642798,DB0015810047461_,4.108769325,0.822859472,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,folic acid,DB00158
,83931,DB00213,10047461,56,18839,28,13393,0.149263877,1.42182147,0.8874778,2.326018681,0.282960856,DB0021310047461_,1.262446708,0.351938775,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,83943,DB00158,10069868,70,16745,20,8084,0.041842488,1.689666107,1.0150631,2.935142618,0.109422369,DB0015810069868_,2.212539942,0.52453094,NA,10069868,Device issue,10077536,Product issues,Prod,folic acid,DB00158
,83946,DB00563,10069868,203,46443,71,15277,0.673843565,0.940488324,0.713957158,1.25120926,0.802191087,DB0056310069868_,0.220408436,-0.061356045,NA,10069868,Device issue,10077536,Product issues,Prod,methotrexate,DB00563
,83952,DB00316,10074902,49,65425,25,36928,0.718095992,1.106299563,0.670046732,1.869566189,0.833522203,DB0031610074902_,0.182094939,0.101020719,NA,10074902,Expired product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,83958,DB00273,10029148,58,8423,30,2163,0.003183425,0.496493168,0.313401918,0.801470286,0.014201684,DB0027310029148_,4.254394709,-0.700185556,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,topiramate,DB00273
,83967,DB00811,10044565,23,2775,31,4125,0.780959414,1.102859923,0.612685334,1.95844876,0.880700697,DB0081110044565_,0.127037442,0.097906736,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,ribavirin,DB00811
,83970,DB00028,10022061,125,13333,30,5585,0.005867191,1.745311152,1.162363773,2.697432326,0.023259047,DB0002810022061_,3.761061105,0.55693285,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,83973,DB00028,10053483,346,13112,105,5510,0.003383465,1.384772607,1.107311089,1.743611198,0.014905617,DB0002810053483_,4.206017142,0.325535944,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,83974,DB00028,10053505,317,13141,80,5535,2.79722130099032e-05,1.668968091,1.299363963,2.164916506,0.000266975,DB0002810053505_,8.228354899,0.512205526,NA,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,83975,DB00213,10022004,117,18778,39,13382,1.94835629289109e-05,2.137865752,1.47528857,3.157860176,0.000195207,DB0021310022004_,8.541450244,0.759808019,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,83976,DB00213,10052904,106,18789,50,13371,0.017929384,1.508656356,1.067226664,2.157852287,0.05670142,DB0021310052904_,2.869956028,0.411219424,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,83977,DB00213,10061224,48,18847,24,13397,0.187675635,1.421642425,0.853340981,2.427876383,0.333663909,DB0021310061224_,1.097621053,0.35181284,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,83978,DB01050,10024264,68,18040,57,9314,0.007946175,0.615925067,0.42641244,0.892602566,0.029630475,DB0105010024264_,3.518951879,-0.484629967,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,83979,DB01050,10073317,47,18061,22,9349,0.799506929,1.105847543,0.652888381,1.928235315,0.891657918,DB0105010073317_,0.11467272,0.100612048,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,83984,DB00635,10043255,41,33012,11,23783,0.00276589,2.685186206,1.355146115,5.793899193,0.012649224,DB0063510043255_,4.370159418,0.987750076,NA,10043255,Tendonitis,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,83985,DB00059,10000081,47,780,75,1032,0.345731617,0.829207945,0.556327812,1.225540581,0.515167548,DB0005910000081_,0.663263096,-0.187284317,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,pegaspargase,DB00059
,83986,DB00694,10000081,36,598,46,725,0.909045943,0.948837842,0.587541671,1.522135723,0.959147103,DB0069410000081_,0.041710824,-0.052517368,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,daunorubicin,DB00694
,83990,DB00563,10001497,29,46617,32,15316,3.72444638456173e-06,0.297756273,0.17372386,0.508371554,4.56183938575047e-05,DB0056310001497_,9.995199549,-1.211480003,male,10001497,Agitation,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,83991,DB00635,10001497,60,32993,62,23732,0.053278419,0.696117293,0.479672009,1.009584748,0.13113805,DB0063510001497_,2.031504694,-0.362237109,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,84007,DB00541,10014625,29,3105,38,4259,0.901319598,1.046817644,0.621169007,1.747120912,0.956927891,DB0054110014625_,0.044027239,0.045754747,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,vincristine,DB00541
,84017,DB00541,10021036,20,3114,55,4242,0.00657874,0.495405141,0.280626205,0.841900728,0.025489707,DB0054110021036_,3.66948054,-0.702379385,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,vincristine,DB00541
,84019,DB00987,10021036,15,2089,41,2887,0.028358561,0.505676486,0.259268702,0.936055577,0.081070724,DB0098710021036_,2.512433371,-0.68185817,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,cytarabine,DB00987
,84037,DB00059,10038695,38,789,35,1072,0.116803899,1.474812065,0.898063755,2.428313105,0.236313923,DB0005910038695_,1.442594177,0.388530568,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pegaspargase,DB00059
,84038,DB00541,10038695,72,3062,102,4195,0.876655666,0.967073437,0.702429193,1.325597628,0.947351087,DB0054110038695_,0.054085518,-0.033480843,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vincristine,DB00541
,84040,DB00059,10040047,74,753,62,1045,0.00520915,1.655903507,1.14969533,2.391616124,0.021141814,DB0005910040047_,3.856502473,0.504346786,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,pegaspargase,DB00059
,84047,DB00541,10071066,60,3074,46,4251,0.002856596,1.803580472,1.204303635,2.716818649,0.012993188,DB0054110071066_,4.343330089,0.58977384,NA,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,vincristine,DB00541
,84048,DB00635,10071066,107,32946,70,23724,0.542796823,1.100728367,0.806424875,1.510509689,0.698014408,DB0063510071066_,0.359515535,0.095972113,NA,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,84059,DB08910,10013786,60,16684,35,17453,0.005482478,1.793257112,1.162134726,2.805421436,0.022022914,DB0891010013786_,3.815671805,0.584033582,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,pomalidomide,DB08910
,84064,DB00186,10002368,33,16868,25,9983,0.345115844,0.781237864,0.4503291,1.371245181,0.514527096,DB0018610002368_,0.66450706,-0.246875612,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,84067,DB00996,10002368,56,38897,46,22379,0.080083677,0.70044347,0.465563598,1.058422628,0.178533518,DB0099610002368_,1.722978918,-0.356041616,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,84069,DB01224,10002368,27,8081,38,5879,0.011220916,0.516949774,0.303170539,0.870298111,0.039039282,DB0122410002368_,3.243186921,-0.659809558,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,84071,DB06218,10002855,40,1654,38,1398,0.64615067,0.889743371,0.552883038,1.433996604,0.781649463,DB0621810002855_,0.246348896,-0.116822205,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,lacosamide,DB06218
,84072,DB00186,10008469,122,16779,40,9968,0.000795094,1.81189298,1.257118963,2.66113606,0.00455161,DB0018610008469_,5.392274248,0.594372144,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,84073,DB00213,10008469,128,18767,66,13355,0.034100726,1.380099892,1.016746298,1.888324799,0.093602504,DB0021310008469_,2.368698139,0.322155882,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,84075,DB00404,10008469,143,19749,42,9820,0.002180389,1.692957597,1.191593511,2.450786099,0.010445915,DB0040410008469_,4.561544255,0.526477057,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,84076,DB00656,10008469,74,11939,38,6581,0.767068076,1.073428219,0.71558464,1.633793516,0.871962305,DB0065610008469_,0.137009084,0.07085747,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,84077,DB01068,10008469,70,13693,25,6815,0.189611596,1.393545407,0.870490136,2.298948622,0.336026214,DB0106810008469_,1.090566105,0.331851152,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,84082,DB00404,10011469,90,19802,14,9848,8.22198242352e-06,3.196979907,1.808841845,6.084570249,9.16517421553109e-05,DB0040410011469_,9.297514575,1.162206585,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,84083,DB00656,10011469,49,11964,7,6612,0.000203326,3.86839057,1.741655232,10.12924287,0.001461227,DB0065610011469_,6.52847911,1.352838547,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,84084,DB00996,10011469,113,38840,26,22399,5.54904401943919e-06,2.506386685,1.624355695,4.002177784,6.47675941611718e-05,DB0099610011469_,9.64470517,0.918842148,NA,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,84085,DB01068,10011469,84,13679,16,6824,0.000162997,2.618946754,1.521053444,4.794530483,0.00121079,DB0106810011469_,6.716482217,0.962772235,NA,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,84088,DB00213,10019063,87,18808,74,13347,0.262233342,0.83432115,0.604386918,1.154277525,0.42398947,DB0021310019063_,0.858046659,-0.181136878,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,84090,DB00404,10019063,115,19777,64,9798,0.473769927,0.89022321,0.649498905,1.229416576,0.639650848,DB0040410019063_,0.446832802,-0.116283051,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,84091,DB00656,10019063,63,11950,85,6534,5.64568760915831e-08,0.405277516,0.287415784,0.568890208,1.07846583435121e-06,DB0065610019063_,13.73997105,-0.903183221,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,84092,DB01068,10019063,115,13648,143,6697,2.43426346134709e-13,0.394632156,0.305463434,0.508937572,1.18930511303919e-11,DB0106810019063_,25.15506682,-0.929801199,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,84093,DB01202,10019063,48,6666,39,5679,0.914127418,1.048542513,0.671785108,1.645731343,0.961536643,DB0120210019063_,0.039222604,0.047401117,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,84096,DB00996,10019303,176,38777,77,22348,0.049456732,1.317299407,1.001762653,1.745965715,0.123995633,DB0099610019303_,2.087508935,0.275583737,NA,10019303,Heart rate increased,10022891,Investigations,Inv,gabapentin,DB00996
,84097,DB01068,10019303,89,13674,31,6809,0.098056613,1.429581744,0.939220945,2.229085658,0.207940143,DB0106810019303_,1.570505013,0.357381915,NA,10019303,Heart rate increased,10022891,Investigations,Inv,clonazepam,DB01068
,84110,DB01068,10022437,409,13354,180,6660,0.182905287,1.133203193,0.946232825,1.361425098,0.327553429,DB0106810022437_,1.116104094,0.125048306,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,84126,DB00996,10027566,47,38906,13,22412,0.015738738,2.08263569,1.108258586,4.196835729,0.051191709,DB0099610027566_,2.972177702,0.73363425,NA,10027566,Micturition urgency,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,84141,DB00996,10033864,34,38919,31,22394,0.070861524,0.63111858,0.376285314,1.062103196,0.162828495,DB0099610033864_,1.81505781,-0.46026151,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,84142,DB01224,10033864,35,8073,54,5863,0.000509632,0.470736668,0.298177805,0.734673806,0.003135693,DB0122410033864_,5.764905088,-0.753456433,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,84172,DB00186,10038743,54,16847,40,9968,0.286516381,0.798784046,0.52051672,1.234948899,0.451300859,DB0018610038743_,0.795621068,-0.22466465,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,84174,DB00404,10038743,50,19842,31,9831,0.34490701,0.799162104,0.50022096,1.295041694,0.514332441,DB0040410038743_,0.664885451,-0.224191471,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,84175,DB00656,10038743,37,11976,34,6585,0.034311333,0.598355994,0.365022382,0.983764805,0.094023498,DB0065610038743_,2.364210552,-0.513569394,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,84176,DB00996,10038743,53,38900,48,22377,0.02310417,0.635199893,0.421486097,0.959355676,0.069162264,DB0099610038743_,2.671299884,-0.453815537,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,84177,DB01068,10038743,49,13714,37,6803,0.065608048,0.656945532,0.419560022,1.036635807,0.153494218,DB0106810038743_,1.87409238,-0.420154169,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,84179,DB01224,10038743,55,8053,43,5874,0.758684385,0.932981028,0.61373006,1.426528318,0.865388781,DB0122410038743_,0.144576416,-0.069370413,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,84191,DB00028,10029148,37,13421,16,5599,0.880937867,0.964733861,0.523110791,1.85912637,0.950123172,DB0002810029148_,0.051163648,-0.035903008,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,human immunoglobulin g,DB00028
,84205,DB01076,10018852,32,25715,60,25523,0.003346089,0.529360888,0.333373789,0.826500958,0.01477191,DB0107610018852_,4.215027904,-0.636084872,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,atorvastatin,DB01076
,84207,DB00264,10020028,41,29566,22,24870,0.099769864,1.567616376,0.911946852,2.764042522,0.210444238,DB0026410020028_,1.558534565,0.449556234,NA,10020028,Hiatus hernia,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,84209,DB00451,10020028,64,47207,9,15410,0.013794863,2.321133576,1.149048417,5.30797367,0.046006214,DB0045110020028_,3.078978809,0.842055677,NA,10020028,Hiatus hernia,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,84221,DB01039,10033371,125,2848,72,2979,6.17486259722299e-05,1.815775637,1.341455101,2.473115685,0.000528427,DB0103910033371_,7.545606442,0.596512725,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,84232,DB00820,10061822,120,11795,37,5779,0.013131574,1.588999779,1.089341877,2.367098952,0.044248884,DB0082010061822_,3.117925135,0.463104749,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,84235,DB00563,10003553,153,46493,30,15318,0.00769967,1.680214527,1.129813694,2.576463953,0.028893688,DB0056310003553_,3.544132126,0.51892148,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,84236,DB00563,10034960,50,46596,13,15335,0.559033381,1.265776881,0.677189,2.540999143,0.711840552,DB0056310034960_,0.339901337,0.235686068,NA,10034960,Photophobia,10015919,Eye disorders,Eye,methotrexate,DB00563
,84251,DB00331,10005191,93,24853,46,20706,0.003614807,1.684366474,1.170201597,2.454493571,0.015724486,DB0033110005191_,4.152536161,0.521389513,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,84252,DB00999,10005191,90,21340,39,12200,0.168810978,1.319288759,0.895924991,1.974923015,0.309266182,DB0099910005191_,1.173552941,0.277092773,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,84253,DB01076,10005191,94,25653,57,25526,0.003237892,1.640933179,1.167932115,2.32314495,0.014395804,DB0107610005191_,4.240818517,0.495265092,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,84258,DB00999,10040753,323,21107,72,12167,2.96023654668871e-15,2.585923325,1.995203413,3.390132563,1.87267912466216e-13,DB0099910040753_,29.30623612,0.95008263,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,84263,DB00625,10000125,13,563,67,1069,0.000598578,0.368594587,0.185012914,0.681156801,0.003589284,DB0062510000125_,5.629802545,-0.998057919,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,efavirenz,DB00625
,84265,DB00625,10013573,19,557,38,1098,1,0.985645397,0.53144805,1.771601872,1,DB0062510013573_,0,-0.014458627,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,efavirenz,DB00625
,84267,DB00537,10005750,50,7507,20,4278,0.212458474,1.424629847,0.831658967,2.530134707,0.3643755,DB0053710005750_,1.009570349,0.353912023,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,ciprofloxacin,DB00537
,84272,DB08932,10019974,120,19323,21,6576,0.003442584,1.944745699,1.215166542,3.258984028,0.015124237,DB0893210019974_,4.191456734,0.665131223,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,macitentan,DB08932
,84273,DB08932,10033425,954,18489,292,6305,0.116759263,1.114126993,0.973090585,1.278565421,0.236253041,DB0893210033425_,1.442851841,0.108071132,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,84277,DB11133,10000059,42,2389,21,1553,0.3644204,1.300042502,0.7494141,2.320322046,0.53405387,DB1113310000059_,0.627258565,0.262396958,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,omega-3 fatty acids,DB11133
,84278,DB00343,10028391,54,8682,19,5076,0.067252511,1.661601981,0.967966778,2.972036079,0.156450327,DB0034310028391_,1.855016717,0.507782186,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diltiazem,DB00343
,84279,DB00641,10028391,78,14046,49,12426,0.061617125,1.408220353,0.971898103,2.057828911,0.14641831,DB0064110028391_,1.921287615,0.342326746,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,84284,DB00421,10005724,76,8827,27,5225,0.023917695,1.666127408,1.059722312,2.6931356,0.071048948,DB0042110005724_,2.644386232,0.510502016,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,spironolactone,DB00421
,84287,DB01233,10021015,51,3370,19,1707,0.307852079,1.359562082,0.786007264,2.44655864,0.47502961,DB0123310021015_,0.74437814,0.307162649,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,metoclopramide,DB01233
,84289,DB00559,10028334,64,9595,19,3287,0.704643432,1.153919221,0.681336182,2.042903661,0.822904333,DB0055910028334_,0.194915327,0.143164167,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,bosentan,DB00559
,84290,DB01233,10028334,42,3379,18,1708,0.680071157,1.179387058,0.662004985,2.183712816,0.806481857,DB0123310028334_,0.215073878,0.164994861,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,metoclopramide,DB01233
,84300,DB00668,10046735,212,9879,53,4250,0.00031262,1.720764166,1.265142735,2.376772768,0.002087607,DB0066810046735_,6.171736756,0.542768475,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,epinephrine,DB00668
,84306,DB01039,10003549,89,2884,100,2951,0.554644707,0.910702433,0.673339953,1.23005104,0.70812299,DB0103910003549_,0.345137486,-0.093539073,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,84315,DB00213,10042682,79,18816,28,13393,0.001113321,2.008206661,1.289331548,3.212542327,0.006015757,DB0021310042682_,5.113373123,0.697242115,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,84317,DB00451,10042682,255,47016,46,15373,9.42116803830123e-05,1.812471436,1.319132344,2.539799635,0.000757642,DB0045110042682_,7.185299118,0.594691348,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,84318,DB00497,10042682,58,19209,31,16344,0.042483508,1.591890507,1.011709721,2.548959572,0.110666371,DB0049710042682_,2.201235275,0.464922308,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,84320,DB00758,10042682,33,8267,18,10056,0.006850247,2.229990136,1.218645167,4.209896699,0.026357131,DB0075810042682_,3.636016408,0.801997162,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,84322,DB00213,10046735,152,18743,56,13365,1.45137129267898e-05,1.935418197,1.414615175,2.681094089,0.000150698,DB0021310046735_,8.800230215,0.660323426,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,84324,DB00497,10046735,104,19163,67,16308,0.077262819,1.320966254,0.9617591,1.824894831,0.173688535,DB0049710046735_,1.750491611,0.278363479,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,84326,DB00758,10046735,74,8226,47,10027,0.000458221,1.919088016,1.312116964,2.831741576,0.00287112,DB0075810046735_,5.853053145,0.651850082,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,clopidogrel,DB00758
,84327,DB00927,10046735,118,7379,37,4979,2.26529387746126e-05,2.151783677,1.473163035,3.209359495,0.000222381,DB0092710046735_,8.411118636,0.766297115,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,famotidine,DB00927
,84329,DB00222,10037660,59,3147,54,3074,0.776108814,1.067266185,0.722620472,1.578963938,0.87794888,DB0022210037660_,0.13016691,0.065100412,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,84342,DB00203,10005555,35,13843,19,8919,0.579876642,1.186816997,0.660097788,2.197849525,0.728534671,DB0020310005555_,0.316720062,0.171274931,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,sildenafil,DB00203
,84345,DB00047,10033371,243,9042,141,8377,1.05465740410407e-05,1.596606989,1.289240045,1.983298062,0.000113683,DB0004710033371_,9.082094148,0.467880746,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,84346,DB01306,10037844,89,4119,72,3794,0.426712899,1.138559902,0.822365568,1.580870662,0.595414817,DB0130610037844_,0.518496945,0.12976422,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,insulin aspart,DB01306
,84352,DB00422,10022998,48,3387,69,2880,0.006419201,0.591576182,0.399097054,0.870671657,0.024982038,DB0042210022998_,3.689598179,-0.52496481,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,methylphenidate,DB00422
,84353,DB00688,10000081,91,6399,71,5307,0.750769616,1.062978822,0.76903074,1.474175144,0.859119693,DB0068810000081_,0.151847026,0.061075177,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,mycophenolate mofetil,DB00688
,84354,DB00864,10000081,120,6749,119,8273,0.115640751,1.23608943,0.949150298,1.609912067,0.234637935,DB0086410000081_,1.449711653,0.211952711,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,84356,DB08931,10011906,1058,5519,570,1876,9.06050801626857e-15,0.630967482,0.561877708,0.70891507,5.38204414028518e-13,DB0893110011906_,28.25053796,-0.460500952,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,84358,DB08931,10043607,62,6515,30,2416,0.239128132,0.766415039,0.486696181,1.231136246,0.396870895,DB0893110043607_,0.924144252,-0.26603143,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,riociguat,DB08931
,84361,DB05259,10020937,319,10951,80,2648,0.748936068,0.964194246,0.749449099,1.252644628,0.857544195,DB0525910020937_,0.153682562,-0.036462505,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,84362,DB00399,10000059,71,6921,41,4957,0.290683034,1.240271395,0.831279531,1.87224663,0.455964883,DB0039910000059_,0.785339483,0.215330223,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,84363,DB00448,10012174,60,5085,50,3074,0.112745959,0.72547608,0.488696434,1.080949941,0.230194774,DB0044810012174_,1.468829483,-0.320927178,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,lansoprazole,DB00448
,84366,DB00399,10028334,155,6837,90,4908,0.116435591,1.236290194,0.944797313,1.625714884,0.235778638,DB0039910028334_,1.444861887,0.212115116,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,84367,DB00448,10028334,74,5071,23,3101,0.004216241,1.967339019,1.214931081,3.299486773,0.017825944,DB0044810028334_,4.027100355,0.676681878,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,lansoprazole,DB00448
,84370,DB00115,10047340,83,18342,27,10445,0.009743504,1.750524112,1.121079274,2.813870075,0.034861228,DB0011510047340_,3.35638001,0.559915235,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,cyanocobalamin,DB00115
,84375,DB00625,10013709,31,545,40,1096,0.073097801,1.558146897,0.931229794,2.585731496,0.166692031,DB0062510013709_,1.791607292,0.443497228,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,efavirenz,DB00625
,84376,DB14126,10013709,45,926,33,1243,0.010217898,1.829915166,1.132013309,2.985413849,0.036180031,DB1412610013709_,3.319247948,0.604269608,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tenofovir,DB14126
,84381,DB00051,10037162,202,25529,112,11308,0.065178252,0.798919205,0.630366562,1.016724945,0.152746999,DB0005110037162_,1.878972325,-0.224495458,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,84383,DB00620,10037162,41,4787,20,3112,0.357192109,1.332645713,0.761401595,2.405765193,0.526912737,DB0062010037162_,0.640720329,0.287166224,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,triamcinolone,DB00620
,84390,DB00879,10059866,12,1765,49,3663,0.038144108,0.50830458,0.245413758,0.972719744,0.101881708,DB0087910059866_,2.283942862,-0.676674445,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,emtricitabine,DB00879
,84393,DB01118,10053762,62,3001,80,4629,0.299436043,1.195390575,0.841024037,1.692299418,0.465445085,DB0111810053762_,0.764761159,0.178472973,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,amiodarone,DB01118
,84395,DB00480,10020100,367,67061,257,67405,8.12135969308316e-06,1.435330096,1.220025586,1.690654402,9.06839165389511e-05,DB0048010020100_,9.308130542,0.361394855,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,84402,DB01229,10016288,175,5566,124,2585,0.000505661,0.655466865,0.515224889,0.835928947,0.003116538,DB0122910016288_,5.771032449,-0.422407527,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,paclitaxel,DB01229
,84415,DB08907,10038435,33,4220,54,3856,0.009295494,0.558443724,0.349963965,0.879069693,0.033564401,DB0890710038435_,3.394289271,-0.582601427,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,canagliflozin,DB08907
,84416,DB00480,10041101,53,67375,35,67627,0.055308618,1.519936524,0.973286277,2.400512404,0.134882127,DB0048010041101_,2.003354014,0.418668573,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,84419,DB00281,10070863,225,11233,149,5522,0.00640509,0.742314578,0.599296987,0.921692211,0.024940049,DB0028110070863_,3.691280371,-0.297982166,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,lidocaine,DB00281
,84425,DB00264,10013786,136,29471,100,24792,0.326227004,1.144067539,0.876731798,1.497177376,0.494738742,DB0026410013786_,0.703725449,0.134589929,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,84426,DB00641,10013786,59,14065,55,12420,0.778716099,0.94724042,0.644295383,1.39471796,0.879365569,DB0064110013786_,0.128554576,-0.054202342,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,84428,DB00641,10015150,104,14020,70,12405,0.079891212,1.314555282,0.960665874,1.807932605,0.178240506,DB0064110015150_,1.724621486,0.27349842,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,84432,DB00264,10040829,127,29480,57,24835,5.63665675195857e-05,1.876958813,1.362216753,2.614040236,0.000489113,DB0026410040829_,7.622917295,0.629652814,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,84433,DB00641,10040829,58,14066,30,12445,0.018190511,1.71049191,1.081838092,2.755425169,0.057330644,DB0064110040829_,2.858919991,0.536780996,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,84458,DB00448,10005750,37,5108,19,3105,0.583370024,1.183763992,0.662146961,2.183243202,0.731448009,DB0044810005750_,0.312729135,0.168699185,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,lansoprazole,DB00448
,84466,DB08908,10020642,67,10606,14,3265,0.236019476,1.473193752,0.818604144,2.842322647,0.393253585,DB0890810020642_,0.93330062,0.387432665,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,dimethyl fumarate,DB08908
,84473,DB01075,10016334,89,19859,36,11061,0.112184528,1.376956524,0.924462038,2.089974925,0.229333513,DB0107510016334_,1.472577947,0.319875646,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,84474,DB01012,10033425,47,10585,23,8662,0.053354535,1.672188439,0.994301917,2.887717899,0.13130081,DB0101210033425_,2.030264327,0.514133211,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,cinacalcet,DB01012
,84481,DB00316,10067152,54,65420,8,36945,5.68993742550884e-05,3.811920983,1.802680338,9.275793117,0.00049319,DB0031610067152_,7.614615142,1.338133257,female,10067152,Oral herpes,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,84484,DB00451,10067152,43,47228,9,15410,0.261255708,1.558886198,0.749352673,3.63792309,0.422799304,DB0045110067152_,0.860857671,0.443971591,NA,10067152,Oral herpes,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,84495,DB00103,10013968,12,382,41,617,0.027997423,0.473039571,0.223404819,0.931567858,0.080212791,DB0010310013968_,2.523072283,-0.748576234,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,agalsidase beta,DB00103
,84498,DB00814,10003988,226,8061,83,3332,0.375432251,1.125487432,0.868412385,1.470408117,0.545311896,DB0081410003988_,0.606397362,0.118216215,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,84499,DB00814,10006784,43,8244,10,3405,0.128613425,1.775942648,0.877513008,3.968373675,0.25364675,DB0081410006784_,1.371812728,0.574331351,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,84501,DB00814,10037087,180,8107,62,3353,0.225394137,1.200723627,0.892273785,1.634324951,0.380213381,DB0081410037087_,0.967022655,0.182924398,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,meloxicam,DB00814
,84502,DB00814,10042674,71,8216,17,3398,0.044899635,1.727247124,1.004894646,3.133604098,0.115376568,DB0081410042674_,2.159553997,0.546528883,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,84503,DB00814,10046735,69,8218,19,3396,0.126546376,1.500706225,0.890919719,2.645683348,0.250868957,DB0081410046735_,1.38282456,0.405935814,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,meloxicam,DB00814
,84504,DB00678,10013781,97,15502,47,10677,0.050407505,1.421443064,0.992460906,2.06093845,0.125785472,DB0067810013781_,2.07317743,0.351672598,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,84505,DB00471,10016766,39,14150,21,5444,0.247437821,0.714521014,0.409696472,1.279694275,0.406661867,DB0047110016766_,0.899773233,-0.336142872,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,84506,DB01068,10016766,39,13724,12,6828,0.179676896,1.616913775,0.828771814,3.394179731,0.323452145,DB0106810016766_,1.128704104,0.480519255,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,84507,DB01104,10016766,40,15423,15,7271,0.562876336,1.257125105,0.6789482,2.451471224,0.715037793,DB0110410016766_,0.33541988,0.228827451,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,84508,DB01068,10017885,73,13690,24,6816,0.083739202,1.514361699,0.942462493,2.51433742,0.184662521,DB0106810017885_,1.689225328,0.41499403,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,84512,DB01104,10043431,41,15422,20,7266,0.891301216,0.965870612,0.552610261,1.741390143,0.954816394,DB0110410043431_,0.046236214,-0.034725396,NA,10043431,Thinking abnormal,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,84514,DB08895,10061623,213,27901,38,6608,0.12535759,1.327521825,0.935498625,1.929729083,0.249160468,DB0889510061623_,1.389658141,0.283313914,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,84515,DB00959,10016825,113,7965,49,4953,0.034671784,1.434013923,1.014827632,2.052336762,0.094793826,DB0095910016825_,2.356050994,0.360477451,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,methylprednisolone,DB00959
,84531,DB00987,10053762,57,2047,100,2828,0.162927292,0.787511455,0.555679211,1.106974365,0.301269354,DB0098710053762_,1.19975055,-0.238877362,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cytarabine,DB00987
,84543,DB00193,10012374,63,19257,26,8676,0.818581899,1.091681748,0.680721081,1.797786848,0.90321487,DB0019310012374_,0.101794803,0.087719395,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,84545,DB09068,10012378,94,2301,31,955,0.316049519,1.258389665,0.824060905,1.968679919,0.483713998,DB0906810012378_,0.72626146,0.22983286,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,vortioxetine,DB09068
,84551,DB00193,10029216,62,19258,20,8682,0.231724492,1.397585509,0.832034038,2.444539501,0.387997953,DB0019310029216_,0.946755214,0.334746111,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,84552,DB01104,10029216,66,15397,21,7265,0.134121139,1.482918114,0.894971616,2.553913626,0.261506871,DB0110410029216_,1.34129472,0.394011845,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,84556,DB01104,10033664,76,15387,28,7258,0.292926209,1.280265622,0.819393515,2.053491703,0.458500051,DB0110410033664_,0.779794877,0.247067573,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,84557,DB00193,10040753,314,19006,45,8657,1.89925861634459e-16,3.17811943,2.317169128,4.450993817,1.3752620586947e-14,DB0019310040753_,31.917547,1.156289648,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,tramadol,DB00193
,84558,DB00335,10040753,122,8344,25,5440,6.73890090788029e-09,3.181348612,2.052809724,5.114843842,1.56986639554243e-07,DB0033510040753_,15.66710513,1.157305199,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,atenolol,DB00335
,84560,DB00193,10041466,54,19266,10,8692,0.006506892,2.43618672,1.227519843,5.368449049,0.025265329,DB0019310041466_,3.678322217,0.890433997,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,84575,DB01240,10038695,147,5604,47,1529,0.375544897,0.85334728,0.607362489,1.217956077,0.5453851,DB0124010038695_,0.606263129,-0.158588687,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,84577,DB00999,10016288,40,21390,36,12203,0.055454003,0.633928438,0.393664177,1.024033523,0.135076311,DB0099910016288_,2.001915394,-0.455819205,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,hydrochlorothiazide,DB00999
,84581,DB00588,10042128,83,16441,31,8437,0.137701579,1.373955239,0.898672105,2.149966428,0.266491387,DB0058810042128_,1.322413356,0.317693616,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,84582,DB00761,10042128,92,15215,27,8598,0.002089527,1.925477645,1.240969216,3.079476982,0.010087836,DB0076110042128_,4.596424943,0.655174064,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,84588,DB00333,10013654,418,2653,574,2578,7.14538468834292e-07,0.707681366,0.615282674,0.813492196,1.06411578772291e-05,DB0033310013654_,11.45078126,-0.345761334,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,methadone,DB00333
,84592,DB00295,10074903,80,14583,69,9533,0.093444403,0.757941461,0.541776221,1.062673392,0.200822548,DB0029510074903_,1.605333604,-0.277149125,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,84602,DB00423,10016173,111,2356,42,998,0.587659184,1.119473048,0.771672438,1.650182171,0.734656832,DB0042310016173_,0.308351784,0.112858082,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,methocarbamol,DB00423
,84603,DB00921,10016173,61,5784,27,4876,0.005003748,1.904452744,1.190065935,3.122111569,0.02048015,DB0092110016173_,3.888299152,0.644194694,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,buprenorphine,DB00921
,84605,DB00575,10024855,49,5195,29,3800,0.420687711,1.235907521,0.763771785,2.033152465,0.589676035,DB0057510024855_,0.528181986,0.211805535,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,84612,DB00996,10039020,39,38914,89,22336,4.19541202951736e-14,0.251530365,0.167981007,0.370539873,2.24824475424799e-12,DB0099610039020_,26.82087131,-1.380191561,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,84614,DB05676,10006451,268,46861,75,25254,1.49103988407415e-07,1.925698655,1.484812903,2.523509071,2.60931979712976e-06,DB0567610006451_,12.85642098,0.65528884,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,apremilast,DB05676
,84618,DB05676,10042682,49,47080,12,25317,0.01072539,2.195766296,1.150725699,4.536287306,0.037641616,DB0567610042682_,3.27964504,0.786531095,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,84624,DB00537,10008479,68,7489,41,4257,0.764771667,0.942773353,0.629421596,1.427681341,0.870160954,DB0053710008479_,0.13907708,-0.058929372,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,84626,DB11089,10008479,190,9985,118,8289,0.015214839,1.336651892,1.05469735,1.699696403,0.0498687,DB1108910008479_,2.998361736,0.290167899,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,84631,DB11089,10013911,54,10121,43,8364,0.918657565,1.037809497,0.681605525,1.588725423,0.964056956,DB1108910013911_,0.036604903,0.037112239,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,docusate,DB11089
,84642,DB05676,10017944,439,46690,253,25076,0.378346857,0.931921417,0.795879558,1.093016259,0.548333314,DB0567610017944_,0.60087194,-0.070506784,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,84647,DB05676,10033557,159,46970,42,25287,1.55220155716863e-05,2.03807636,1.442023254,2.937216263,0.00015956,DB0567610033557_,8.743087444,0.712006402,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,apremilast,DB05676
,84648,DB05676,10047513,66,47063,39,25290,0.682211932,0.909390064,0.602881669,1.388302606,0.80781785,DB0567610047513_,0.213418679,-0.094981164,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,apremilast,DB05676
,84649,DB00381,10020751,261,29099,115,22772,1.56628438294271e-07,1.776062506,1.419807718,2.233081145,2.72958006437069e-06,DB0038110020751_,12.81136278,0.574398839,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,amlodipine,DB00381
,84650,DB00758,10020751,61,8239,64,10010,0.418542066,1.157990921,0.80087991,1.672965774,0.587586296,DB0075810020751_,0.531732158,0.146686539,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,clopidogrel,DB00758
,84651,DB00343,10012174,111,8625,81,5014,0.131798116,0.796668206,0.591539032,1.076768555,0.258318804,DB0034310012174_,1.353560783,-0.22731699,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,diltiazem,DB00343
,84665,DB00904,10061273,45,23024,34,14422,0.419450516,0.829056543,0.519079448,1.335304893,0.588423413,DB0090410061273_,0.5303085,-0.18746692,NA,10061273,Malnutrition,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,84675,DB06228,10061428,187,15725,142,15934,0.010700264,1.334387412,1.065862377,1.673557614,0.037568482,DB0622810061428_,3.281589827,0.288472319,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,rivaroxaban,DB06228
,84676,DB08911,10061428,22,1617,38,1710,0.069231737,0.612334504,0.343355737,1.067338029,0.159949155,DB0891110061428_,1.832899293,-0.490476571,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,trametinib,DB08911
,84677,DB08912,10061428,15,1315,35,1499,0.021530175,0.488667548,0.246775497,0.923126496,0.065530413,DB0891210061428_,2.725240918,-0.716072881,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,dabrafenib,DB08912
,84692,DB08904,10000081,129,11481,45,3514,0.471532465,0.877393521,0.618992666,1.263712368,0.637743293,DB0890410000081_,0.449819439,-0.130799675,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,certolizumab pegol,DB08904
,84693,DB08904,10012735,283,11327,87,3472,1,0.997084751,0.778971467,1.28691862,1,DB0890410012735_,0,-0.002919507,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,certolizumab pegol,DB08904
,84694,DB08904,10021789,202,11408,76,3483,0.133361667,0.811492077,0.618569601,1.073840223,0.260463796,DB0890410021789_,1.345291407,-0.208880655,NA,10021789,Infection,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,84697,DB08904,10008479,44,11566,11,3548,0.634133935,1.227024339,0.622722265,2.637365944,0.772481079,DB0890410008479_,0.258147764,0.204592002,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,84698,DB05676,10006002,78,47051,25,25304,0.022813895,1.677922543,1.057153145,2.749257571,0.068458614,DB0567610006002_,2.681525895,0.517556447,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,84701,DB00584,10002855,32,2049,19,1855,0.159451243,1.52458451,0.834993883,2.857337684,0.296709917,DB0058410002855_,1.215000329,0.42172192,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,enalapril,DB00584
,84702,DB00177,10005750,125,4675,62,2788,0.251526533,1.202277843,0.876395339,1.663898721,0.41151368,DB0017710005750_,0.887913014,0.18421796,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,valsartan,DB00177
,84703,DB00584,10005750,41,2040,29,1845,0.335758675,1.278570246,0.771990914,2.142725664,0.504929873,DB0058410005750_,0.683335725,0.245742459,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,enalapril,DB00584
,84707,DB00973,10016322,71,3780,27,2994,0.000957009,2.082596442,1.316108718,3.384062266,0.005313122,DB0097310016322_,5.237575603,0.733615405,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,84710,DB00973,10022004,29,3822,39,2982,0.027236327,0.580219968,0.345155378,0.965227558,0.07852439,DB0097310022004_,2.544346001,-0.544347993,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,84711,DB00584,10037660,29,2052,51,1823,0.003197262,0.505260378,0.307389688,0.81636274,0.01425253,DB0058410037660_,4.250820831,-0.682681383,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,enalapril,DB00584
,84712,DB00973,10037660,51,3800,48,2973,0.361027294,0.831292157,0.547669082,1.263494863,0.530946256,DB0097310037660_,0.633094476,-0.184773973,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,84715,DB00641,10046543,34,14090,19,12456,0.12921655,1.581918847,0.876571142,2.937418419,0.254492509,DB0064110046543_,1.368483876,0.45863857,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,simvastatin,DB00641
,84736,DB00996,10016330,41,38912,19,22406,0.503204502,1.242575096,0.704828857,2.267241217,0.664364157,DB0099610016330_,0.408924851,0.217185917,NA,10016330,Feeling drunk,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,84740,DB01240,10005483,45,5706,20,1556,0.093433612,0.613611624,0.353760539,1.100404243,0.200809689,DB0124010005483_,1.60539764,-0.488393085,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,epoprostenol,DB01240
,84741,DB00264,10005851,54,29553,41,24851,0.680482406,1.107488433,0.724065073,1.705498869,0.806696585,DB0026410005851_,0.21480766,0.102094779,NA,10005851,Blood urea increased,10022891,Investigations,Inv,metoprolol,DB00264
,84743,DB01076,10005851,44,25703,58,25525,0.165886822,0.753373702,0.497069374,1.134693346,0.305324215,DB0107610005851_,1.186381068,-0.283193891,NA,10005851,Blood urea increased,10022891,Investigations,Inv,atorvastatin,DB01076
,84745,DB00169,10020919,114,38577,62,18113,0.37323072,0.863338398,0.627876791,1.196695948,0.542954284,DB0016910020919_,0.610730155,-0.146948547,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,84746,DB00264,10020919,147,29460,103,24789,0.161787805,1.200893911,0.926616912,1.561156468,0.299773893,DB0026410020919_,1.204726777,0.183066206,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,84748,DB00381,10020919,170,29190,110,22777,0.131332837,1.2059156,0.942588152,1.548023395,0.257656638,DB0038110020919_,1.356127442,0.187239112,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,84749,DB00437,10020919,64,6857,70,11476,0.015452194,1.530068735,1.071418395,2.18196361,0.050457908,DB0043710020919_,2.986615797,0.425312659,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,allopurinol,DB00437
,84751,DB00264,10038428,117,29490,113,24779,0.319786169,0.869997856,0.665634027,1.137501363,0.487916382,DB0026410038428_,0.717611237,-0.139264531,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,84752,DB00338,10038428,121,33553,89,22183,0.480129288,0.898847247,0.677600001,1.196143122,0.644957114,DB0033810038428_,0.438571454,-0.106642173,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,84754,DB00381,10038428,126,29234,125,22762,0.055971507,0.784851803,0.607519354,1.013995379,0.136034309,DB0038110038428_,1.994848154,-0.242260365,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,84755,DB01240,10038428,53,5698,12,1564,0.649966849,1.212263778,0.6375766,2.498696468,0.784694958,DB0124010038428_,0.242460225,0.192489503,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,epoprostenol,DB01240
,84763,DB08895,10047942,123,27991,25,6621,0.531257799,1.163772762,0.751697969,1.869460009,0.688107584,DB0889510047942_,0.373810081,0.151667109,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,tofacitinib,DB08895
,84766,DB00813,10000891,28,10544,30,10138,0.695340196,0.897400148,0.516213142,1.555555268,0.816576211,DB0081310000891_,0.202635032,-0.10825342,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,fentanyl,DB00813
,84767,DB00904,10000891,47,23022,34,14422,0.568006108,0.865974342,0.544975302,1.389152407,0.719034895,DB0090410000891_,0.32984539,-0.143899999,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,ondansetron,DB00904
,84792,DB00813,10043071,89,10483,130,10038,0.002191785,0.655571372,0.4941786,0.866403447,0.010483319,DB0081310043071_,4.557969994,-0.4222481,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,fentanyl,DB00813
,84801,DB08890,10016173,68,1879,22,537,0.607100711,0.883379971,0.533389771,1.515601835,0.750030184,DB0889010016173_,0.287641828,-0.123999853,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,linaclotide,DB08890
,84802,DB01409,10038687,42,5989,15,3951,0.041598403,1.8470776,1.001903841,3.590999136,0.108932903,DB0140910038687_,2.217023158,0.613604715,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,84804,DB00425,10013952,63,12632,23,7461,0.056522705,1.617810934,0.988463634,2.735745948,0.136997008,DB0042510013952_,1.987796194,0.48107396,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,84805,DB00476,10013952,62,17195,10,6167,0.015355381,2.223656963,1.130856144,4.868024888,0.050222883,DB0047610013952_,2.991284516,0.799153121,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,84811,DB00331,10005654,45,24901,15,20737,0.001624737,2.498215499,1.366371293,4.826616627,0.008199392,DB0033110005654_,4.803695277,0.915576677,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,metformin,DB00331
,84819,DB00331,10020583,30,24916,24,20728,1,1.039900099,0.587553765,1.859346993,1,DB0033110020583_,0,0.03912465,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,84839,DB01050,10018884,88,18020,97,9274,3.13466232168302e-07,0.466904326,0.345455337,0.630350137,5.08608636576778e-06,DB0105010018884_,12.18900191,-0.761630911,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ibuprofen,DB01050
,84841,DB00451,10066152,105,47166,26,15393,0.223963607,1.317965352,0.850900863,2.111147208,0.378488094,DB0045110066152_,0.971570663,0.276089147,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,levothyroxine,DB00451
,84846,DB01142,10013709,96,1644,35,749,0.287519415,1.249490071,0.831468596,1.915363465,0.452433418,DB0114210013709_,0.793114669,0.222735525,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,doxepin,DB01142
,84857,DB00627,10013968,56,1273,54,1545,0.242829426,1.258513086,0.843704545,1.878643379,0.401066416,DB0062710013968_,0.91362824,0.229930933,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,niacin,DB00627
,84858,DB01261,10013968,160,3621,112,3191,0.072181279,1.258883693,0.977803227,1.625303597,0.165074601,DB0126110013968_,1.801357778,0.230225371,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sitagliptin,DB01261
,84861,DB08901,10013709,30,477,29,551,0.506303258,1.194768924,0.681984007,2.096017164,0.667126908,DB0890110013709_,0.404774984,0.177952798,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ponatinib,DB08901
,84862,DB00158,10020772,205,16610,78,8026,0.074220261,1.26990159,0.972434626,1.672554747,0.168557072,DB0015810020772_,1.780480879,0.238939409,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,folic acid,DB00158
,84864,DB00482,10020772,104,8155,23,3048,0.020847554,1.690021878,1.065479883,2.78821369,0.063855731,DB0048210020772_,2.751128937,0.524741474,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,celecoxib,DB00482
,84865,DB00836,10020772,84,5451,48,4027,0.183275959,1.292801468,0.89399732,1.888157481,0.327971446,DB0083610020772_,1.114828729,0.256811545,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,loperamide,DB00836
,84867,DB00836,10037087,104,5431,38,4037,0.00010993,2.034206872,1.387093197,3.039668172,0.000864733,DB0083610037087_,7.053089734,0.710105999,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,loperamide,DB00836
,84869,DB00572,10037844,67,2835,35,2091,0.105796451,1.411816952,0.920670734,2.198687767,0.219848186,DB0057210037844_,1.514818034,0.344877493,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,atropine,DB00572
,84870,DB00836,10037844,160,5375,77,3998,0.001724235,1.545517848,1.16658446,2.062236886,0.008603457,DB0083610037844_,4.75559122,0.435359031,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,loperamide,DB00836
,84871,DB00158,10046306,210,16605,50,8054,1.96237007809205e-06,2.037094335,1.48838855,2.835257228,2.60312377000502e-05,DB0015810046306_,10.55621329,0.711524447,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,folic acid,DB00158
,84873,DB00482,10046306,67,8192,12,3059,0.015517236,2.084810282,1.116410221,4.240870372,0.050616847,DB0048210046306_,2.983470813,0.734677859,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,celecoxib,DB00482
,84875,DB00836,10046306,39,5496,11,4064,0.003690641,2.621408492,1.314730135,5.682146063,0.015990853,DB0083610046306_,4.135738397,0.963711766,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,loperamide,DB00836
,84876,DB01097,10046306,83,6182,12,1491,0.115730475,1.668076709,0.902855977,3.36710438,0.234774681,DB0109710046306_,1.449129029,0.511671292,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,leflunomide,DB01097
,84877,DB08907,10037087,32,4221,22,3888,0.339248799,1.339743853,0.7531757,2.424552813,0.50836068,DB0890710037087_,0.676564084,0.292478441,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,canagliflozin,DB08907
,84879,DB00544,10051055,20,2415,46,2607,0.004164468,0.469435505,0.262226701,0.8122874,0.017648212,DB0054410051055_,4.037120778,-0.75622436,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,fluorouracil,DB00544
,84894,DB00046,10048959,82,5377,68,4624,0.86909105,1.037012584,0.740793702,1.455574891,0.941770587,DB0004610048959_,0.059993572,0.036344064,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,84895,DB01307,10048959,47,2477,33,2036,0.571147311,1.1706329,0.731192542,1.893872112,0.721482462,DB0130710048959_,0.326447209,0.157544543,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,insulin detemir,DB01307
,84897,DB00451,10012431,53,47218,13,15406,0.394269981,1.330173528,0.715116139,2.660709495,0.564208757,DB0045110012431_,0.572330959,0.285309406,NA,10012431,Dermatitis,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,84899,DB00295,10005483,32,14631,62,9540,3.64438260414409e-07,0.336551754,0.212345595,0.524143424,5.81618680934592e-06,DB0029510005483_,12.0548657,-1.08900334,male,10005483,Blood creatinine increased,10022891,Investigations,Inv,morphine,DB00295
,84911,DB05676,10043414,370,46759,257,25072,0.001831123,0.771979045,0.656084305,0.909393446,0.009051238,DB0567610043414_,4.704853758,-0.258797874,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,84912,DB05676,10052904,182,46947,83,25246,0.220755399,1.179150856,0.904275622,1.548515492,0.374425718,DB0567610052904_,0.982361844,0.164794566,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,84920,DB01268,10013946,93,2050,128,3002,0.674903711,1.06395594,0.800763795,1.409344909,0.802871355,DB0126810013946_,0.219560783,0.06199398,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,84921,DB00321,10000081,119,7328,32,2818,0.081356784,1.429952516,0.958314768,2.189647122,0.180643948,DB0032110000081_,1.711227322,0.357641238,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,amitriptyline,DB00321
,84922,DB00741,10000081,106,3988,68,3106,0.245831448,1.21403602,0.883547918,1.677662276,0.404739316,DB0074110000081_,0.904512083,0.193950363,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,hydrocortisone,DB00741
,84926,DB00455,10000087,151,9250,46,5072,0.000389468,1.799867177,1.283568741,2.566205891,0.002508497,DB0045510000087_,5.988071577,0.587712871,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,84927,DB01175,10000087,142,10582,36,4856,0.001095404,1.810014839,1.245802774,2.691418962,0.005935414,DB0117510000087_,5.126818578,0.593335044,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,84928,DB01592,10000087,83,6193,35,3032,0.491247202,1.160985729,0.771256815,1.780714194,0.654429745,DB0159210000087_,0.423991041,0.14926941,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,84932,DB00321,10001949,45,7402,17,2833,1,1.013122868,0.56744177,1.891368218,1,DB0032110001949_,0,0.013037509,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,84933,DB00335,10001949,38,8428,19,5446,0.415745306,1.292328075,0.725905062,2.375849927,0.584972184,DB0033510001949_,0.536190982,0.256445301,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,84934,DB00338,10001949,136,33538,69,22203,0.074120312,1.30485462,0.96915014,1.770486362,0.168402835,DB0033810001949_,1.781396341,0.266091632,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,84935,DB00451,10001949,220,47051,53,15366,0.048449066,1.355598799,0.999720337,1.867174708,0.122174289,DB0045110001949_,2.102306653,0.304243275,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,84938,DB00829,10001949,38,8014,16,4438,0.395530853,1.315211064,0.715131252,2.529705732,0.565182304,DB0082910001949_,0.570606939,0.273997158,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,84939,DB01224,10001949,42,8066,27,5890,0.627486417,1.135861452,0.683265283,1.918178249,0.766909446,DB0122410001949_,0.265386548,0.127391351,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,84944,DB00321,10002855,164,7283,44,2806,0.034413469,1.435938822,1.020744661,2.057400111,0.094234612,DB0032110002855_,2.361967739,0.361818867,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,amitriptyline,DB00321
,84945,DB00741,10002855,71,4023,27,3147,0.0013574,2.056817005,1.300028526,3.341668087,0.007083433,DB0074110002855_,4.949996576,0.721159645,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,hydrocortisone,DB00741
,84950,DB00455,10003239,245,9156,90,5028,0.001162633,1.494863996,1.166324166,1.930051007,0.00624186,DB0045510003239_,5.076477056,0.40203523,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,84951,DB00829,10003239,197,7855,56,4398,4.0574978149832e-06,1.969544285,1.453320392,2.706219592,4.91707376979407e-05,DB0082910003239_,9.920211874,0.677802189,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,diazepam,DB00829
,84956,DB00321,10003988,157,7290,42,2808,0.037397849,1.439750159,1.015420059,2.081307177,0.100378072,DB0032110003988_,2.298811504,0.364469598,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,amitriptyline,DB00321
,84957,DB00557,10003988,110,5877,27,3040,0.00034997,2.107247598,1.369383914,3.34802947,0.00229429,DB0055710003988_,6.077331684,0.74538264,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxyzine,DB00557
,84958,DB00829,10003988,186,7866,65,4389,0.001068767,1.59659946,1.194542561,2.157006816,0.005816259,DB0082910003988_,5.147098093,0.46787603,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diazepam,DB00829
,84963,DB00321,10010305,111,7336,44,2806,0.85653099,0.964938062,0.672777806,1.405163514,0.931058148,DB0032110010305_,0.071433546,-0.035691364,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,amitriptyline,DB00321
,84964,DB00476,10010305,1064,16193,402,5775,0.34266294,0.943929627,0.837423794,1.065499498,0.51195904,DB0047610010305_,0.669510657,-0.057703663,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,84965,DB01175,10010305,132,10592,95,4797,0.000870132,0.629294791,0.478632687,0.829957278,0.004912775,DB0117510010305_,5.315916416,-0.463155466,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,84966,DB01592,10010305,59,6217,42,3025,0.069624621,0.683526247,0.451271982,1.043465021,0.160639293,DB0159210010305_,1.828593841,-0.380490222,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,iron,DB01592
,84970,DB00321,10011224,109,7338,27,2823,0.042479793,1.553082389,1.008801531,2.468542602,0.110662177,DB0032110011224_,2.201273167,0.440241594,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amitriptyline,DB00321
,84971,DB00335,10011224,150,8316,66,5399,0.00921721,1.475483516,1.095083048,2.006170273,0.03335491,DB0033510011224_,3.400550278,0.388985744,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atenolol,DB00335
,84972,DB00455,10011224,282,9119,120,4998,0.022726917,1.287996349,1.03357141,1.612935033,0.068256058,DB0045510011224_,2.684489094,0.253087793,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,84973,DB00829,10011224,104,7948,39,4415,0.042956843,1.481251119,1.013994856,2.203043987,0.111600752,DB0082910011224_,2.192827489,0.392887081,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diazepam,DB00829
,84974,DB01175,10011224,210,10514,75,4817,0.070991438,1.282761339,0.978676295,1.696785915,0.163013011,DB0117510011224_,1.81392526,0.24901505,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,84975,DB01224,10011224,66,8042,37,5880,0.229413971,1.304208836,0.857904254,2.00975332,0.385183373,DB0122410011224_,0.954035764,0.265596601,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,quetiapine,DB01224
,84980,DB00321,10012378,156,7291,51,2799,0.346965682,1.174251668,0.848098933,1.649326219,0.516391651,DB0032110012378_,0.660889788,0.160631066,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,amitriptyline,DB00321
,84981,DB00741,10012378,62,4032,28,3146,0.018205959,1.727580424,1.086000968,2.811275557,0.057358699,DB0074110012378_,2.858430769,0.546721831,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,hydrocortisone,DB00741
,84987,DB00104,10013573,36,1445,23,1054,0.689887902,1.141599696,0.65384882,2.030831748,0.812970053,DB0010410013573_,0.207061005,0.132430521,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,octreotide,DB00104
,84989,DB11074,10013573,40,1220,23,845,0.517549506,1.2044479,0.697954537,2.124251901,0.677142298,DB1107410013573_,0.389873839,0.186021288,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,dimethicone,DB11074
,84994,DB00476,10013774,49,17208,7,6170,0.021461406,2.509982788,1.130017092,6.572241709,0.065355158,DB0047610013774_,2.727918914,0.920275896,NA,10013774,Dry eye,10015919,Eye disorders,Eye,duloxetine,DB00476
,85005,DB00321,10013781,53,7394,22,2828,0.795614605,0.921411451,0.549673952,1.594124321,0.889335739,DB0032110013781_,0.117280456,-0.081848598,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,amitriptyline,DB00321
,85006,DB00335,10013781,72,8394,22,5443,0.001386728,2.122054736,1.299104244,3.598043246,0.007207147,DB0033510013781_,4.932682106,0.752384834,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,85007,DB00338,10013781,229,33445,112,22160,0.009017278,1.354732368,1.075297087,1.714936588,0.032769136,DB0033810013781_,3.418268192,0.30360392,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,85009,DB01175,10013781,47,10677,24,4868,0.700585532,0.892881535,0.534369457,1.528511204,0.82000671,DB0117510013781_,0.198442755,-0.113301366,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,85010,DB01224,10013781,39,8069,25,5892,0.703883502,1.139070997,0.671336107,1.966245264,0.82243856,DB0122410013781_,0.195481498,0.130213015,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,quetiapine,DB01224
,85018,DB01156,10013952,44,13578,13,6315,0.156907641,1.574120023,0.831960465,3.187943803,0.293326507,DB0115610013952_,1.226468932,0.4536964,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,85025,DB00104,10013968,37,1444,26,1051,1,1.035761334,0.606275198,1.793475973,1,DB0010410013968_,0,0.035136745,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,octreotide,DB00104
,85027,DB11074,10013968,47,1213,44,824,0.156112164,0.725749025,0.465956139,1.132136041,0.292288264,DB1107410013968_,1.230014757,-0.32055102,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dimethicone,DB11074
,85030,DB00316,10013990,167,65307,86,36867,0.51267078,1.096225808,0.839883115,1.439514958,0.672851533,DB0031610013990_,0.396230578,0.091873196,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,85034,DB00476,10013990,42,17215,22,6155,0.155495925,0.682582963,0.397977315,1.201648517,0.291475157,DB0047610013990_,1.2328005,-0.381871202,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,duloxetine,DB00476
,85048,DB00451,10016100,68,47203,31,15388,0.128814705,0.715092875,0.460966611,1.132091457,0.253929392,DB0045110016100_,1.370699033,-0.33534285,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,85061,DB00169,10018870,48,38643,30,18145,0.225368203,0.751265673,0.466255885,1.228445531,0.380206232,DB0016910018870_,0.967041457,-0.285995931,NA,10018870,Blood urine present,10022891,Investigations,Inv,cholecalciferol,DB00169
,85062,DB00316,10018870,65,65409,59,36894,0.00870894,0.621385483,0.429978656,0.899697934,0.03188737,DB0031610018870_,3.445545278,-0.475803644,NA,10018870,Blood urine present,10022891,Investigations,Inv,acetaminophen,DB00316
,85075,DB00104,10019211,60,1421,23,1054,0.006618526,1.934470279,1.169484434,3.301034553,0.025617428,DB0010410019211_,3.664482391,0.659833532,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,octreotide,DB00104
,85079,DB00316,10019304,84,65390,42,36911,0.577883851,1.128965868,0.770385655,1.676799476,0.726762345,DB0031610019304_,0.319155753,0.121302052,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,acetaminophen,DB00316
,85082,DB00451,10019304,95,47176,23,15396,0.23872292,1.347954978,0.847334412,2.228978226,0.396426191,DB0045110019304_,0.925265406,0.298588613,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,levothyroxine,DB00451
,85095,DB01592,10022437,121,6155,39,3028,0.02175851,1.526266505,1.052846059,2.255632285,0.066064739,DB0159210022437_,2.717120126,0.422824561,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,iron,DB01592
,85100,DB00321,10028411,81,7366,24,2826,0.323510508,1.294781007,0.8105279,2.140358736,0.491942594,DB0032110028411_,0.709393249,0.258341574,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,amitriptyline,DB00321
,85101,DB00335,10028411,113,8353,55,5410,0.094782775,1.330643576,0.953942988,1.875165082,0.20292169,DB0033510028411_,1.59493514,0.285662717,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,85102,DB00455,10028411,81,9320,37,5081,0.438987719,1.193442314,0.798137567,1.814577325,0.607368786,DB0045510028411_,0.498619117,0.176841832,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,85103,DB00476,10028411,213,17044,50,6127,0.005965297,1.531301104,1.119090599,2.130736688,0.023557367,DB0047610028411_,3.748316681,0.426117769,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,85104,DB00557,10028411,58,5929,24,3043,0.413461491,1.240262394,0.75690579,2.091795814,0.582852585,DB0055710028411_,0.539820981,0.215322965,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxyzine,DB00557
,85105,DB00741,10028411,54,4040,24,3150,0.021636523,1.754192112,1.063279605,2.974384527,0.065804572,DB0074110028411_,2.721065967,0.562008416,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocortisone,DB00741
,85106,DB00829,10028411,92,7960,30,4424,0.01019131,1.704321317,1.115748094,2.671164071,0.036102235,DB0082910028411_,3.321400491,0.533166977,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,diazepam,DB00829
,85107,DB01592,10028411,74,6202,26,3041,0.163985671,1.395503616,0.879785584,2.27871717,0.302736576,DB0159210028411_,1.194892236,0.333255365,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,iron,DB01592
,85112,DB00169,10029410,128,38563,48,18127,0.195599702,1.253462326,0.892587719,1.786019247,0.343771242,DB0016910029410_,1.067778837,0.225909583,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,85114,DB00451,10029410,142,47129,54,15365,0.360610181,0.857339548,0.622202411,1.196357842,0.530540614,DB0045110029410_,0.633858767,-0.153921234,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,85125,DB01156,10037087,203,13419,64,6264,0.006519078,1.480606759,1.110845611,1.99626699,0.025299568,DB0115610037087_,3.676967956,0.392451976,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,bupropion,DB01156
,85130,DB00169,10042128,266,38425,60,18115,4.6638217001201e-08,2.090017298,1.573193259,2.815659971,9.0638486793092e-07,DB0016910042128_,13.91380182,0.737172342,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,85132,DB00335,10042128,48,8418,27,5438,0.635831572,1.148462354,0.701373072,1.91663071,0.773634813,DB0033510042128_,0.256655335,0.138423964,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,85134,DB00741,10042128,30,4064,47,3127,0.002489218,0.491173824,0.29920748,0.795131346,0.011623574,DB0074110042128_,4.454719984,-0.710957194,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,hydrocortisone,DB00741
,85137,DB01592,10042128,34,6242,19,3048,0.660827649,0.873828908,0.483561553,1.624447901,0.792999212,DB0159210042128_,0.231933051,-0.13487068,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,85142,DB00321,10046571,131,7316,20,2830,3.07134097515752e-05,2.533414094,1.571624707,4.292357636,0.000289667,DB0032110046571_,8.146778513,0.929567837,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,amitriptyline,DB00321
,85143,DB00335,10046571,211,8255,53,5412,2.06419716727955e-11,2.609868064,1.918944533,3.604396037,7.48378241957834e-10,DB0033510046571_,21.01311259,0.95929967,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,atenolol,DB00335
,85144,DB00741,10046571,90,4004,31,3143,4.10823973456122e-05,2.278653014,1.495366971,3.556879539,0.000373182,DB0074110046571_,7.893443997,0.823584485,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,hydrocortisone,DB00741
,85145,DB01592,10046571,167,6109,57,3010,0.01737551,1.443517294,1.059006917,1.992254349,0.05534601,DB0159210046571_,2.894150706,0.367082701,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,iron,DB01592
,85180,DB00399,10040753,82,6910,38,4960,0.025584114,1.548881698,1.040100571,2.343654277,0.07479462,DB0039910040753_,2.59300932,0.437533186,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,zoledronic acid,DB00399
,85193,DB08827,10010774,45,1117,17,565,0.34001346,1.338726562,0.74331682,2.518513713,0.509172699,DB0882710010774_,0.674968028,0.291718835,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,lomitapide,DB08827
,85194,DB00448,10028411,60,5085,28,3096,0.270068045,1.304637047,0.817966385,2.127415196,0.432704798,DB0044810028411_,0.837699543,0.265924877,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lansoprazole,DB00448
,85197,DB01098,10074903,72,8077,46,7163,0.095259486,1.38806356,0.944298519,2.058538831,0.203610132,DB0109810074903_,1.591548231,0.327909653,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,rosuvastatin,DB01098
,85198,DB05676,10068319,115,47014,51,25278,0.289381158,1.212356943,0.864271501,1.721473868,0.454519494,DB0567610068319_,0.788514475,0.192566351,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,85203,DB00654,10007559,24,3792,32,2566,0.013391309,0.507561771,0.285343535,0.891579748,0.044928274,DB0065410007559_,3.102687962,-0.678136859,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,latanoprost,DB00654
,85210,DB00512,10030124,40,4697,42,5056,0.912215827,1.025176158,0.646713668,1.622936589,0.960594091,DB0051210030124_,0.040203341,0.02486446,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,85218,DB08932,10007515,151,19292,85,6512,0.000284738,0.599659715,0.455990152,0.79296194,0.00193394,DB0893210007515_,6.24819565,-0.511392927,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,macitentan,DB08932
,85220,DB00451,10000084,73,47198,20,15399,0.548033324,1.19085592,0.717799763,2.063109185,0.702539216,DB0045110000084_,0.353054056,0.174672309,NA,10000084,Abdominal pain lower,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,85224,DB00814,10021789,91,8196,32,3383,0.485813786,1.173769317,0.775059207,1.819108607,0.649853199,DB0081410021789_,0.431008789,0.160220209,NA,10021789,Infection,10021881,Infections and infestations,Infec,meloxicam,DB00814
,85241,DB00275,10013573,104,1956,67,1170,0.685187467,0.928508324,0.670380247,1.293173888,0.809887557,DB0027510013573_,0.210859859,-0.074175933,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,olmesartan,DB00275
,85246,DB00656,10061428,197,11816,124,6495,0.240019811,0.873290905,0.692564772,1.104632526,0.397868721,DB0065610061428_,0.921633174,-0.135486555,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,trazodone,DB00656
,85247,DB00515,10029354,86,1784,93,2058,0.701781865,1.066715693,0.780646703,1.456369818,0.821004821,DB0051510029354_,0.197226297,0.064584482,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,cisplatin,DB00515
,85248,DB00215,10022998,58,11045,37,5239,0.185873861,0.743536941,0.483299762,1.156928864,0.331304116,DB0021510022998_,1.104718546,-0.29633683,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,85249,DB00215,10047513,79,11024,23,5253,0.04279512,1.636649064,1.016368242,2.732606332,0.11130161,DB0021510047513_,2.195511552,0.492650898,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,citalopram,DB00215
,85255,DB01174,10013710,37,902,14,778,0.009607128,2.278445401,1.192567122,4.597910964,0.034481239,DB0117410013710_,3.367339914,0.823493369,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,phenobarbital,DB01174
,85257,DB00009,10002424,129,1222,105,1446,0.006273222,1.45357061,1.101729112,1.921145498,0.0245411,DB0000910002424_,3.707406001,0.374023019,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,alteplase,DB00009
,85266,DB00104,10011906,80,1401,80,997,0.038817657,0.71174348,0.509762104,0.993733702,0.103276696,DB0010410011906_,2.270343525,-0.340037714,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,octreotide,DB00104
,85267,DB00193,10011906,693,18627,552,8150,8.03871855044195e-24,0.549282532,0.488958365,0.617274873,1.1483571581433e-21,DB0019310011906_,48.21595459,-0.599142339,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,85268,DB00258,10011906,50,628,64,679,0.434411184,0.844796294,0.562197119,1.263632922,0.60298883,DB0025810011906_,0.505856606,-0.168659752,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,calcium acetate,DB00258
,85276,DB01076,10018830,43,25704,37,25546,0.57628866,1.155014322,0.726584386,1.844167349,0.72557108,DB0107610018830_,0.320796238,0.144112744,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,85282,DB00193,10018836,39,19281,26,8676,0.139120361,0.674970759,0.400323405,1.155608551,0.26857469,DB0019310018836_,1.314626228,-0.393085909,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,85283,DB00213,10018836,88,18807,48,13373,0.162736495,1.30360801,0.906272894,1.89521648,0.301001251,DB0021310018836_,1.200640859,0.265135813,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,85285,DB00343,10018836,35,8701,17,5078,0.568211418,1.201577193,0.654554068,2.289592908,0.719227546,DB0034310018836_,0.329577496,0.183635021,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,85293,DB00193,10021789,179,19141,74,8628,0.585135876,1.090347104,0.826081137,1.451478586,0.732691637,DB0019310021789_,0.311030352,0.086496089,NA,10021789,Infection,10021881,Infections and infestations,Infec,tramadol,DB00193
,85294,DB00213,10021789,184,18711,131,13290,1,0.997641485,0.792143535,1.25932317,1,DB0021310021789_,0,-0.002361301,NA,10021789,Infection,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,85296,DB00343,10021789,81,8655,39,5056,0.343140266,1.213217146,0.816839112,1.829313105,0.512447526,DB0034310021789_,0.668556962,0.19327563,NA,10021789,Infection,10021881,Infections and infestations,Infec,diltiazem,DB00343
,85297,DB00646,10021789,50,3403,32,1968,0.64620824,0.903633599,0.566286786,1.460768897,0.781673134,DB0064610021789_,0.246318613,-0.101331312,NA,10021789,Infection,10021881,Infections and infestations,Infec,nystatin,DB00646
,85298,DB01306,10021789,47,4161,41,3825,0.830819198,1.053784026,0.676655027,1.646993411,0.911439174,DB0130610021789_,0.092730419,0.052387521,NA,10021789,Infection,10021881,Infections and infestations,Infec,insulin aspart,DB01306
,85299,DB06674,10021789,65,4441,20,1470,0.899437385,1.075757964,0.640709852,1.881842911,0.956490275,DB0667410021789_,0.044484657,0.073025496,NA,10021789,Infection,10021881,Infections and infestations,Infec,golimumab,DB06674
,85302,DB00193,10022595,38,19282,21,8681,0.48168261,0.814698669,0.465812163,1.462095822,0.646267541,DB0019310022595_,0.436541711,-0.204936965,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,tramadol,DB00193
,85310,DB06674,10028813,156,4350,24,1466,0.000151605,2.190406773,1.4124665,3.536048458,0.001137619,DB0667410028813_,6.778817901,0.784087268,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,golimumab,DB06674
,85346,DB00381,10016825,172,29188,64,22823,1.57530517598242e-07,2.101383844,1.567590114,2.8472219,2.74127087392903e-06,DB0038110016825_,12.80708892,0.742596101,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,85348,DB00678,10016825,79,15520,33,10691,0.015756317,1.649039863,1.084653099,2.558327795,0.051240928,DB0067810016825_,2.971216691,0.500193217,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,losartan,DB00678
,85349,DB00927,10016825,105,7392,47,4969,0.019833771,1.501705149,1.052784735,2.170128924,0.061351064,DB0092710016825_,2.79114277,0.406601228,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,famotidine,DB00927
,85351,DB00381,10043521,85,29275,28,22859,3.65995100410248e-05,2.370321373,1.529806892,3.776241367,0.000337906,DB0038110043521_,7.992743079,0.863025547,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,85352,DB00927,10043521,56,7441,11,5005,4.51418036983911e-05,3.423971451,1.772608714,7.255523034,0.000405174,DB0092710043521_,7.811193742,1.23080112,female,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,85353,DB00996,10043521,77,38876,29,22396,0.054805576,1.529602726,0.985864321,2.433184296,0.133996331,DB0099610043521_,2.009942857,0.425008045,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,85385,DB00956,10007559,34,5780,22,3445,0.782640771,0.921132366,0.522376004,1.656118138,0.881770796,DB0095610007559_,0.125823125,-0.082151533,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,hydrocodone,DB00956
,85386,DB00480,10025310,62,67366,82,67580,0.112916855,0.758503312,0.536307109,1.068087048,0.230481036,DB0048010025310_,1.467586691,-0.276408114,NA,10025310,Lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,85387,DB00471,10000081,220,13969,59,5406,0.012623459,1.442964421,1.07611999,1.960986726,0.042871972,DB0047110000081_,3.149537003,0.366699623,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,85405,DB00820,10037383,34,11881,19,5797,0.661099,0.873137358,0.483615823,1.621802959,0.793234301,DB0082010037383_,0.23163664,-0.135662395,NA,10037383,Pulmonary fibrosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,85407,DB00480,10005396,67,67361,59,67603,0.477035834,1.139671097,0.790976644,1.645801606,0.642426832,DB0048010005396_,0.442502349,0.13073971,NA,10005396,Blood calcium increased,10022891,Investigations,Inv,lenalidomide,DB00480
,85415,DB00367,10012735,61,22739,12,455,2.2542497098389e-08,0.101752299,0.053781954,0.209090428,4.66742446814616e-07,DB0036710012735_,14.57748824,-2.285213862,male,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,levonorgestrel,DB00367
,85420,DB00682,10011703,33,19426,17,16347,0.117672332,1.633476088,0.883726681,3.128050836,0.23769585,DB0068210011703_,1.436763362,0.490710313,NA,10011703,Cyanosis,10047065,Vascular disorders,Vasc,warfarin,DB00682
,85426,DB00364,10013968,166,2584,73,1327,0.291463889,1.167771924,0.874085774,1.57241119,0.456944312,DB0036410013968_,0.783193752,0.155097595,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sucralfate,DB00364
,85427,DB00364,10016322,44,2706,15,1385,0.211851872,1.501218268,0.816026396,2.914952282,0.36362325,DB0036410016322_,1.011636976,0.406276957,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,sucralfate,DB00364
,85430,DB06403,10016322,378,21093,93,6568,0.043133169,1.265602289,1.004401955,1.608336402,0.111931617,DB0640310016322_,2.189867155,0.235548126,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,85432,DB00736,10016807,85,10506,30,5523,0.061557473,1.48944772,0.970544318,2.343296366,0.146310646,DB0073610016807_,1.922023205,0.398405393,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,esomeprazole,DB00736
,85433,DB01409,10016807,83,5948,49,3917,0.591480265,1.115500552,0.772445177,1.625868626,0.737822975,DB0140910016807_,0.304051354,0.10930323,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,tiotropium,DB01409
,85435,DB00471,10037423,59,14130,13,5452,0.065776102,1.75114176,0.948568414,3.483391652,0.153751049,DB0047110037423_,1.872420551,0.560268009,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,85436,DB00736,10037423,40,10551,18,5535,0.678501054,1.16573986,0.6523851,2.162468173,0.805292042,DB0073610037423_,0.216550283,0.153355959,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,85439,DB01409,10037423,59,5972,26,3940,0.094948953,1.497056251,0.927098871,2.479239959,0.203136353,DB0140910037423_,1.593877836,0.403500681,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,85441,DB00471,10061822,85,14104,12,5453,0.000373062,2.738304648,1.487396893,5.512189332,0.002419425,DB0047110061822_,6.024225177,1.007338987,female,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,85442,DB00682,10061822,121,19338,59,16305,0.000526022,1.729159255,1.255663607,2.403948737,0.003218563,DB0068210061822_,5.738820321,0.547635311,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,85445,DB01409,10061822,36,5995,23,3943,1,1.029465613,0.592590318,1.82255587,1,DB0140910061822_,0,0.029039846,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,85447,DB00864,10038533,26,6843,33,8359,0.896694143,0.962422124,0.552233674,1.661035957,0.956301489,DB0086410038533_,0.044682051,-0.038302126,NA,10038533,Renal transplant,10042613,Surgical and medical procedures,Surg,tacrolimus,DB00864
,85448,DB00108,10040753,68,10126,14,3281,0.155030667,1.573705539,0.87529884,3.034134309,0.290820803,DB0010810040753_,1.235047999,0.453433054,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,natalizumab,DB00108
,85478,DB00338,10008611,46,33628,14,22258,0.008258114,2.174740967,1.174403607,4.284586767,0.030544504,DB0033810008611_,3.488570516,0.776909562,NA,10008611,Cholecystectomy,10042613,Surgical and medical procedures,Surg,omeprazole,DB00338
,85493,DB01062,10038435,38,4448,17,1728,0.651457489,0.868421757,0.476918505,1.645485917,0.785872774,DB0106210038435_,0.240960365,-0.141077787,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,oxybutynin,DB01062
,85497,DB01075,10038695,113,19835,83,11014,0.061315772,0.756012997,0.563860964,1.017102019,0.145860453,DB0107510038695_,1.925104918,-0.279696711,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,85499,DB01075,10040047,169,19779,146,10951,0.000115704,0.640871314,0.50987488,0.80636976,0.000903796,DB0107510040047_,7.008906516,-0.444926601,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,85500,DB01104,10040047,117,15346,77,7209,0.024836902,0.713790974,0.530094031,0.965846389,0.07313482,DB0110410040047_,2.615450694,-0.337165113,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,sertraline,DB01104
,85522,DB01020,10021097,46,1767,78,1800,0.007826086,0.600842584,0.405515881,0.881607658,0.029259467,DB0102010021097_,3.5315521,-0.509422302,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,isosorbide mononitrate,DB01020
,85523,DB06605,10021097,365,13708,307,12726,0.211149208,1.103732193,0.943840616,1.291428703,0.362689556,DB0660510021097_,1.014208029,0.09869734,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,apixaban,DB06605
,85529,DB00541,10047216,28,3106,58,4239,0.078648605,0.658894561,0.402995486,1.054337012,0.176061675,DB0054110047216_,1.736920918,-0.417191756,NA,10047216,Venoocclusive liver disease,10019805,Hepatobiliary disorders,Hepat,vincristine,DB00541
,85531,DB00864,10047216,20,6849,32,8360,0.402760195,0.762899318,0.413116406,1.376809578,0.572519429,DB0086410047216_,0.557708606,-0.270629212,NA,10047216,Venoocclusive liver disease,10019805,Hepatobiliary disorders,Hepat,tacrolimus,DB00864
,85534,DB01234,10047216,19,31606,40,32848,0.012654127,0.493673239,0.26999171,0.872730537,0.04294838,DB0123410047216_,3.147756342,-0.705881441,NA,10047216,Venoocclusive liver disease,10019805,Hepatobiliary disorders,Hepat,dexamethasone,DB01234
,85540,DB00374,10035528,69,17647,24,5700,0.71835169,0.928623472,0.575516863,1.547001882,0.833618427,DB0037410035528_,0.181979503,-0.074051927,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,treprostinil,DB00374
,85546,DB00682,10038153,70,19389,55,16309,0.720032687,1.07056956,0.740826704,1.553788613,0.834758372,DB0068210038153_,0.180612971,0.068190806,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,warfarin,DB00682
,85548,DB00682,10047942,166,19293,115,16249,0.117952006,1.215722466,0.951754757,1.557350274,0.238105252,DB0068210047942_,1.435042469,0.195338522,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,warfarin,DB00682
,85561,DB00682,10046555,21,19438,52,16312,1.5373133066296e-05,0.338909766,0.193814617,0.572770692,0.000158342,DB0068210046555_,8.750755271,-1.082021383,male,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,warfarin,DB00682
,85562,DB00559,10062352,44,9615,16,3290,0.881971044,0.940977075,0.519726318,1.78900395,0.950618512,DB0055910062352_,0.050642441,-0.060836502,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,bosentan,DB00559
,85563,DB00682,10062352,57,19402,28,16336,0.021576043,1.713991112,1.071672374,2.800207355,0.06565251,DB0068210062352_,2.723379441,0.538824635,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,85565,DB00722,10025082,44,25359,38,25994,0.442010952,1.186883381,0.751120023,1.883283241,0.610138529,DB0072210025082_,0.49406925,0.171330864,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,85594,DB00688,10061818,40,6450,31,5347,0.811935811,1.06968103,0.651557146,1.771168848,0.898995888,DB0068810061818_,0.106476818,0.067360501,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,85596,DB00215,10037884,40,11063,11,5265,0.132389891,1.73053229,0.870591815,3.742600627,0.259116656,DB0021510037884_,1.35047691,0.548429044,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,citalopram,DB00215
,85612,DB00682,10007556,37,19422,37,16327,0.484498806,0.840650807,0.518094004,1.364016033,0.648671902,DB0068210007556_,0.432828233,-0.173578917,NA,10007556,Cardiac failure acute,10007541,Cardiac disorders,Card,warfarin,DB00682
,85614,DB00682,10018870,39,19420,39,16325,0.495158583,0.840634397,0.525022208,1.346038362,0.657505187,DB0068210018870_,0.419302626,-0.173598438,NA,10018870,Blood urine present,10022891,Investigations,Inv,warfarin,DB00682
,85625,DB00476,10062355,116,17141,34,6143,0.352410969,1.222691312,0.826927811,1.850920804,0.52216022,DB0047610062355_,0.649780803,0.201054423,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,85630,DB00472,10020937,116,10643,34,4278,0.122308317,1.371300861,0.926921249,2.077128369,0.244728361,DB0047210020937_,1.407606413,0.315759823,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,85631,DB00996,10020937,574,38379,228,22197,1.25552825177252e-06,1.456045834,1.245615993,1.706615485,1.75214016978182e-05,DB0099610020937_,10.95208747,0.375724429,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,85632,DB01224,10020937,66,8042,29,5888,0.021713905,1.666223935,1.05993151,2.678662863,0.06598266,DB0122410020937_,2.718363304,0.51055995,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,85655,DB01192,10013654,77,691,113,441,1.88668230392973e-07,0.435163806,0.313487208,0.601653452,3.22441120668355e-06,DB0119210013654_,12.6447602,-0.832032753,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,oxymorphone,DB01192
,85660,DB00734,10013983,34,4016,39,4863,0.814696494,1.05568932,0.64513886,1.719851065,0.90059403,DB0073410013983_,0.1047007,0.054193938,NA,10013983,Dystonia,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,85661,DB01224,10013983,40,8068,38,5879,0.251766319,0.767055365,0.478962579,1.230367527,0.411828844,DB0122410013983_,0.887147442,-0.265196296,NA,10013983,Dystonia,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,85662,DB00734,10060933,32,4018,81,4821,0.000268714,0.474062121,0.303857909,0.723729325,0.001844106,DB0073410060933_,6.29576058,-0.746416908,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,85665,DB01224,10006451,46,8062,15,5902,0.005925492,2.24489521,1.229425438,4.333300986,0.023437146,DB0122410006451_,3.753433093,0.808658843,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,quetiapine,DB01224
,85675,DB01306,10009033,32,4176,20,3846,0.209934367,1.47348858,0.815689571,2.723421699,0.361074747,DB0130610009033_,1.018670286,0.387632773,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin aspart,DB01306
,85678,DB01409,10027175,57,5974,26,3940,0.142621982,1.445829201,0.892599955,2.400223545,0.273489295,DB0140910027175_,1.296492799,0.368682998,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,tiotropium,DB01409
,85680,DB01076,10040979,41,25706,73,25510,0.0025887,0.557371258,0.370434269,0.828445247,0.011991186,DB0107610040979_,4.42358339,-0.584523729,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,85685,DB00695,10045285,37,28012,17,20511,0.129248749,1.593641333,0.874911064,3.0190721,0.254527317,DB0069510045285_,1.368347111,0.466021544,NA,10045285,Ulcer,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,85699,DB00695,10061024,271,27778,233,20295,0.070011135,0.849776067,0.709937624,1.017809926,0.161314476,DB0069510061024_,1.824399552,-0.162782415,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,furosemide,DB00695
,85701,DB01118,10061024,37,3026,58,4651,1,0.980509593,0.629343049,1.510650768,1,DB0111810061024_,0,-0.019682849,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,amiodarone,DB01118
,85702,DB01306,10061024,25,4183,30,3836,0.34504004,0.764233084,0.430128177,1.346971744,0.514501628,DB0130610061024_,0.664556559,-0.268882453,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,insulin aspart,DB01306
,85705,DB00199,10012735,85,2625,15,685,0.207945079,1.478559773,0.841291972,2.775221856,0.358759064,DB0019910012735_,1.025104247,0.391068488,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,erythromycin,DB00199
,85707,DB00950,10027175,49,4669,21,2035,1,1.016997207,0.596750972,1.790181478,1,DB0095010027175_,0,0.016854371,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,fexofenadine,DB00950
,85708,DB00973,10027175,51,3800,22,2999,0.0175526,1.829366355,1.086881147,3.17549126,0.055798524,DB0097310027175_,2.886007855,0.603969653,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ezetimibe,DB00973
,85709,DB14500,10027175,121,7688,34,4039,0.000862483,1.869589762,1.26604799,2.827417075,0.004876647,DB1450010027175_,5.323297363,0.625719028,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,potassium,DB14500
,85711,DB00169,10031252,55,38636,32,18143,0.357556112,0.8071289,0.512610581,1.29028047,0.527257358,DB0016910031252_,0.640066504,-0.214271897,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,85717,DB00169,10061822,243,38448,96,18079,0.160922542,1.190224055,0.935360464,1.524675313,0.298739248,DB0016910061822_,1.208184166,0.174141571,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,85719,DB00973,10061822,28,3823,31,2990,0.189892551,0.706465098,0.40731849,1.22022929,0.336376703,DB0097310061822_,1.089523607,-0.34748148,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,85720,DB14500,10061822,52,7757,18,4055,0.164105961,1.5101283,0.867568892,2.746770821,0.302894824,DB1450010061822_,1.194369649,0.412194614,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,85747,DB00213,10016288,102,18793,133,13288,3.88723977164161e-06,0.542289272,0.414386458,0.707885236,4.7391510852319e-05,DB0021310016288_,9.957067441,-0.611955707,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,pantoprazole,DB00213
,85750,DB01610,10016288,33,908,25,1193,0.04386376,1.733835103,0.992257119,3.064917623,0.113301782,DB0161010016288_,2.177700382,0.550335778,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,valganciclovir,DB01610
,85752,DB01377,10035664,226,3570,161,2509,0.915241337,0.986539641,0.797075745,1.223194563,0.962130801,DB0137710035664_,0.03860487,-0.013551771,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,magnesium oxide,DB01377
,85754,DB13867,10038695,64,4486,19,2535,0.015124312,1.90330958,1.122778266,3.372219016,0.049646273,DB1386710038695_,3.002831953,0.643594255,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,85755,DB00213,10040070,96,18799,102,13319,0.004722022,0.666841416,0.49883434,0.890781935,0.019535429,DB0021310040070_,3.935525593,-0.405203018,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,85757,DB00635,10040070,228,32825,218,23576,0.002787928,0.751192585,0.62067148,0.909345876,0.012731757,DB0063510040070_,4.363655891,-0.286093222,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,prednisone,DB00635
,85765,DB00635,10061471,42,33011,52,23742,0.008841059,0.580923443,0.37725456,0.889811298,0.032255844,DB0063510061471_,3.434056028,-0.543136298,NA,10061471,Pseudomonas infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,85774,DB00635,10074171,67,32986,97,23697,1.07627107416634e-05,0.496210546,0.357733045,0.684832725,0.000115634,DB0063510074171_,9.065083105,-0.700754955,NA,10074171,Aspergillus infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,85781,DB00108,10008469,56,10138,7,3288,0.011919428,2.594574855,1.178152956,6.75397653,0.040946504,DB0010810008469_,3.195488849,0.953422671,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,85782,DB00996,10043528,47,38906,22,22403,0.455304484,1.230207592,0.726559579,2.144023663,0.622813789,DB0099610043528_,0.473507699,0.207182929,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,85785,DB00996,10061623,255,38698,180,22245,0.035953795,0.814364593,0.669742968,0.991844965,0.097425022,DB0099610061623_,2.328672198,-0.205347111,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,85790,DB00005,10047940,42,128040,16,42403,0.64891444,0.869341585,0.478537461,1.656587908,0.783838425,DB0000510047940_,0.24355237,-0.140019153,NA,10047940,White blood cell count abnormal,10022891,Investigations,Inv,etanercept,DB00005
,85812,DB01307,10012735,125,2399,84,1985,0.155131889,1.231235475,0.920085305,1.65429507,0.290979534,DB0130710012735_,1.234502345,0.208018116,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,insulin detemir,DB01307
,85813,DB01307,10013573,74,2450,56,2013,0.656172338,1.085739086,0.752867352,1.573152947,0.789738313,DB0130710013573_,0.236053637,0.082260941,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,insulin detemir,DB01307
,85818,DB08895,10047943,49,28065,21,6625,0.031509023,0.55081642,0.323965821,0.967653561,0.0880377,DB0889510047943_,2.429990152,-0.596353702,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,tofacitinib,DB08895
,85876,DB00207,10062355,49,9031,32,5423,0.730665565,0.919502579,0.576361913,1.485565636,0.843350648,DB0020710062355_,0.170372454,-0.083922431,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,85881,DB01039,10028596,19,2954,52,2999,0.000112141,0.370986248,0.206602521,0.640009415,0.000880228,DB0103910028596_,7.035329634,-0.991590285,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,fenofibrate,DB01039
,85884,DB00321,10048294,60,7387,24,2826,0.902559503,0.956411671,0.585400585,1.609183481,0.957195726,DB0032110048294_,0.043747388,-0.04456684,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,amitriptyline,DB00321
,85902,DB01234,10007554,60,31565,104,32784,0.001678076,0.599210881,0.428487238,0.831494688,0.008424296,DB0123410007554_,4.77663539,-0.512141688,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,85908,DB01234,10038687,49,31576,76,32812,0.031343662,0.669981244,0.457878559,0.97234554,0.087664201,DB0123410038687_,2.434241661,-0.40050556,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,85909,DB00087,10053762,63,1306,76,671,1.43134975975188e-06,0.426080312,0.29612989,0.611295007,1.97651843630565e-05,DB0008710053762_,10.83158853,-0.853127425,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,alemtuzumab,DB00087
,85911,DB00760,10053762,28,752,52,963,0.133813318,0.689685755,0.415081306,1.124698571,0.261071299,DB0076010053762_,1.342961734,-0.371519213,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,meropenem,DB00760
,85915,DB06643,10012267,44,52377,14,7501,0.014932353,0.450101743,0.241979451,0.889785938,0.049145044,DB0664310012267_,3.012979273,-0.798281627,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,85916,DB00682,10053483,175,19284,30,16334,4.41983415149572e-21,4.94072663,3.338077408,7.546148169,5.163348474314e-19,DB0068210053483_,42.10753147,1.597512412,female,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,85922,DB01373,10022687,40,22680,14,7367,0.754261325,0.92806219,0.493974133,1.847893973,0.8618771,DB0137310022687_,0.148642594,-0.074656533,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,85926,DB01373,10039117,84,22636,30,7351,0.662873148,0.909286989,0.592333103,1.430755525,0.794492633,DB0137310039117_,0.230051566,-0.095094515,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,85930,DB01373,10039203,65,22655,19,7362,0.799577844,1.111705224,0.657846397,1.964633031,0.891680255,DB0137310039203_,0.114647669,0.105895074,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,85951,DB08932,10020772,230,19213,59,6538,0.056693135,1.326524031,0.991171124,1.799727324,0.13728043,DB0893210020772_,1.985729513,0.282562011,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,macitentan,DB08932
,85952,DB00203,10024690,61,13817,27,8911,0.125062622,1.457040856,0.911305251,2.386578409,0.248715368,DB0020310024690_,1.391446136,0.376407568,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,sildenafil,DB00203
,85953,DB00682,10024690,64,19395,46,16318,0.444013935,1.170569461,0.788484721,1.749864979,0.612009637,DB0068210024690_,0.49100725,0.157490349,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,warfarin,DB00682
,85958,DB05259,10022437,85,11185,26,2702,0.280718622,0.78977414,0.502717669,1.279748682,0.444619866,DB0525910022437_,0.810535595,-0.236008273,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,glatiramer,DB05259
,85966,DB00497,10015090,88,19179,66,16309,0.466437502,1.133793049,0.814074671,1.585730072,0.633177056,DB0049710015090_,0.457005186,0.125568692,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,85968,DB01104,10015090,62,15401,30,7256,0.911077398,0.973663081,0.619429679,1.561335186,0.960018817,DB0110410015090_,0.040802393,-0.026689948,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,85976,DB01104,10016807,84,15379,28,7258,0.127475302,1.415825705,0.912445146,2.258232986,0.252035676,DB0110410016807_,1.378184628,0.347712898,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,sertraline,DB01104
,85987,DB00497,10028735,68,19199,31,16344,0.00332761,1.867297297,1.20355986,2.956537045,0.014707622,DB0049710028735_,4.219389409,0.62449209,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,85989,DB01104,10028735,82,15381,13,7273,5.77970832087096e-05,2.982516806,1.649733899,5.841488775,0.000499736,DB0110410028735_,7.601431328,1.09276751,female,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,85993,DB00370,10030124,41,4500,33,3630,1,1.002221973,0.616854728,1.639620676,1,DB0037010030124_,0,0.002219508,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,85997,DB00804,10047895,84,2916,35,864,0.097860277,0.711178838,0.470253513,1.095554106,0.207674582,DB0080410047895_,1.571782935,-0.34083135,NA,10047895,Weight decreased,10022891,Investigations,Inv,dicyclomine,DB00804
,86000,DB08875,10047895,21,622,52,1191,0.378717621,0.773370286,0.438253986,1.320385555,0.548689138,DB0887510047895_,0.600223232,-0.25699732,NA,10047895,Weight decreased,10022891,Investigations,Inv,cabozantinib,DB08875
,86001,DB00370,10051398,20,4521,41,3622,0.00042115,0.390847474,0.216553328,0.684010596,0.002672977,DB0037010051398_,5.924562632,-0.939437888,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,mirtazapine,DB00370
,86003,DB01104,10051398,29,15434,32,7254,0.001330826,0.425951936,0.248399264,0.727587875,0.006967798,DB0110410051398_,4.966456054,-0.853428766,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sertraline,DB01104
,86009,DB00316,10064774,95,65379,45,36908,0.378583054,1.19174137,0.827264059,1.739591055,0.548600009,DB0031610064774_,0.600385683,0.175415574,NA,10064774,Infusion site extravasation,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,86014,DB01075,10064774,88,19860,36,11061,0.132938234,1.361417013,0.913332175,2.067676359,0.259865503,DB0107510064774_,1.347591076,0.308526079,NA,10064774,Infusion site extravasation,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,86053,DB00982,10005839,102,3262,87,2014,0.032935894,0.72392542,0.535422017,0.980511579,0.091138011,DB0098210005839_,2.395380321,-0.323066903,NA,10005839,Blood triglycerides increased,10022891,Investigations,Inv,isotretinoin,DB00982
,86055,DB00316,10027374,74,65400,31,36922,0.186182122,1.347647318,0.874791739,2.121629124,0.331659183,DB0031610027374_,1.103647395,0.298360345,NA,10027374,Mental impairment,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,86058,DB01592,10041349,68,6208,31,3036,0.829804741,1.072737629,0.69007943,1.701551102,0.91068736,DB0159210041349_,0.093555624,0.070213912,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,iron,DB01592
,86064,DB00005,10073753,470,127612,100,42319,2.89014182142754e-05,1.558574782,1.253193784,1.95462748,0.000274597,DB0000510073753_,8.20020444,0.443771803,NA,10073753,Fear of injection,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,86067,DB08895,10042128,184,27930,15,6631,7.29669414971357e-06,2.912256149,1.718723151,5.313615611,8.22618939417633e-05,DB0889510042128_,9.405602572,1.06892809,female,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,86068,DB00203,10018964,101,13777,53,8885,0.246459808,1.228954757,0.871892889,1.74961715,0.405533572,DB0020310018964_,0.902551617,0.206164017,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,86069,DB00559,10018964,66,9593,33,3273,0.082043858,0.68239468,0.441883657,1.072267626,0.181783337,DB0055910018964_,1.704939757,-0.382147079,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,86070,DB00515,10002034,110,1760,85,2066,0.00507308,1.518941038,1.125574772,2.055568063,0.020698925,DB0051510002034_,3.877673526,0.418013407,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,cisplatin,DB00515
,86088,DB00316,10012218,125,65349,104,36849,0.003756848,0.67777231,0.51814468,0.888046853,0.016214903,DB0031610012218_,4.121824525,-0.388943874,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,86092,DB00316,10057668,165,65309,87,36866,0.645923123,1.070582022,0.820533368,1.404977652,0.781572033,DB0031610057668_,0.24644796,0.068202446,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,86095,DB00399,10001760,137,6855,24,4974,1.95689548401648e-13,4.141550555,2.665552069,6.694964281,9.66860860852881e-12,DB0039910001760_,25.3621367,1.421070248,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,zoledronic acid,DB00399
,86096,DB00451,10003246,318,46953,39,15380,9.00276038455232e-11,2.670981673,1.910160283,3.828994162,2.9450847132291e-09,DB0045110003246_,19.64312826,0.982446073,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,86097,DB14513,10003246,56,7121,14,3550,0.021170448,1.993989713,1.093681516,3.88455903,0.064682424,DB1451310003246_,2.738265762,0.690137513,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,86099,DB14513,10017577,116,7061,41,3523,0.060441065,1.411586339,0.978334793,2.072753505,0.144203812,DB1451310017577_,1.936527622,0.344714135,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,86100,DB00169,10019196,122,38569,61,18114,0.691816412,0.939305711,0.684888591,1.299867641,0.814220538,DB0016910019196_,0.205524019,-0.062614282,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,86101,DB00451,10019196,133,47138,39,15380,0.595714214,1.112682133,0.773103079,1.634349869,0.74122358,DB0045110019196_,0.299452972,0.106773436,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,86102,DB00635,10019196,57,32996,25,23769,0.043204891,1.642403244,1.009356516,2.744358679,0.112083633,DB0063510019196_,2.188509964,0.496160562,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,86103,DB01373,10019196,75,22645,14,7367,0.063209411,1.742717195,0.97616757,3.342428049,0.149319857,DB0137310019196_,1.90166458,0.555445501,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,86109,DB14513,10028372,67,7110,33,3531,1,1.008297468,0.653750223,1.582808628,1,DB1451310028372_,0,0.008263233,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,86110,DB00169,10039203,126,38565,42,18133,0.056525556,1.410595483,0.987104672,2.051922727,0.136997008,DB0016910039203_,1.987796194,0.344011944,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,86112,DB00451,10039203,129,47142,33,15386,0.235226059,1.275817697,0.864309819,1.932105913,0.392267285,DB0045110039203_,0.935811821,0.243587304,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,86113,DB00635,10039203,83,32970,25,23769,5.39548545482904e-05,2.393424431,1.514171224,3.908795388,0.000470929,DB0063510039203_,7.660802747,0.872725157,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,86115,DB00169,10049470,43,38648,7,18168,0.005761783,2.887644723,1.287608446,7.609592979,0.022924161,DB0016910049470_,3.775563843,1.060441195,female,10049470,Bone density decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,86133,DB00399,10068319,56,6936,22,4976,0.015449497,1.826057318,1.095580096,3.145456895,0.050452233,DB0039910068319_,2.98672827,0.602159172,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zoledronic acid,DB00399
,86145,DB00443,10053762,100,2046,24,1166,7.68294165927347e-05,2.374016704,1.498303713,3.900470322,0.000636039,DB0044310053762_,7.360249902,0.864583332,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,betamethasone,DB00443
,86146,DB00741,10053762,135,3959,116,3058,0.437157153,0.898948126,0.692884788,1.167670698,0.605649007,DB0074110053762_,0.501454658,-0.106529948,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocortisone,DB00741
,86163,DB00404,10000059,278,19614,80,9782,7.49283954925338e-06,1.733041416,1.345195322,2.253919723,8.42744063124198e-05,DB0040410000059_,9.381432342,0.549877909,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,86164,DB00497,10000059,193,19074,130,16245,0.043343151,1.264411851,1.006024808,1.593311214,0.11236005,DB0049710000059_,2.186046832,0.234607074,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,86171,DB00497,10010264,270,18997,126,16249,1.09428433864226e-08,1.832847874,1.47645983,2.285169378,2.44170321232697e-07,DB0049710010264_,15.22539982,0.605870972,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,86172,DB00736,10010264,207,10384,75,5478,0.005319957,1.455984967,1.110399735,1.926465578,0.021493249,DB0073610010264_,3.84001638,0.375682625,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,86177,DB00047,10049803,42,9243,36,8482,0.820658701,1.070634297,0.668843842,1.721659329,0.904519726,DB0004710049803_,0.100351166,0.068251273,NA,10049803,Blood glucose fluctuation,10022891,Investigations,Inv,insulin glargine,DB00047
,86184,DB08931,10008469,182,6395,45,2401,0.012407026,1.518478245,1.086316723,2.161427598,0.042270731,DB0893110008469_,3.163660381,0.417708679,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,86186,DB08931,10028735,252,6325,90,2356,0.756962778,1.04294275,0.812656534,1.348393794,0.864024953,DB0893110028735_,0.14615363,0.042046285,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,86187,DB08931,10054112,856,5721,295,2151,0.241423509,1.090985081,0.945682686,1.261055728,0.399535159,DB0893110054112_,0.91745351,0.087081032,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,riociguat,DB08931
,86188,DB08931,10061428,350,6227,113,2333,0.197595829,1.160422266,0.93078068,1.455438108,0.346057852,DB0893110061428_,1.061149317,0.148783961,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,riociguat,DB08931
,86190,DB00959,10003658,64,8014,51,4951,0.178455093,0.775299039,0.527314925,1.144994375,0.321908666,DB0095910003658_,1.133487419,-0.254506467,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,methylprednisolone,DB00959
,86192,DB00005,10062685,55,128027,16,42403,0.7835954,1.138509683,0.642864295,2.128990706,0.882171087,DB0000510062685_,0.125369266,0.129720111,NA,10062685,Hepatic enzyme abnormal,10022891,Investigations,Inv,etanercept,DB00005
,86206,DB00091,10000059,63,5447,17,2653,0.030652183,1.80486017,1.040640408,3.297100107,0.08614794,DB0009110000059_,2.451689224,0.590483121,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,cyclosporine,DB00091
,86207,DB00186,10000059,190,16711,93,9915,0.137940239,1.212112272,0.939745747,1.572655761,0.266841837,DB0018610000059_,1.321099166,0.192364517,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,86210,DB00555,10000059,63,6984,21,3465,0.130074114,1.488349794,0.894093737,2.572800929,0.25581729,DB0055510000059_,1.363291799,0.397667986,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,lamotrigine,DB00555
,86211,DB00688,10000059,90,6400,39,5339,0.000494191,1.924990369,1.305627057,2.884958961,0.003061916,DB0068810000059_,5.78871445,0.654920965,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,mycophenolate mofetil,DB00688
,86212,DB00761,10000059,195,15112,75,8550,0.004098671,1.470993743,1.119946877,1.949077972,0.017422747,DB0076110000059_,4.04997861,0.385938188,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,86219,DB00158,10000060,94,16721,50,8054,0.592707197,0.905546218,0.635212765,1.304440528,0.738881132,DB0015810000060_,0.302618221,-0.099216961,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,86220,DB00186,10000060,142,16759,71,9937,0.255329494,1.185901488,0.884751425,1.601697376,0.416064955,DB0018610000060_,0.87691389,0.170503235,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,86222,DB00370,10000060,30,4511,25,3638,1,0.967758991,0.549119561,1.719384829,1,DB0037010000060_,0,-0.032772199,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,mirtazapine,DB00370
,86227,DB00091,10010264,109,5401,61,2609,0.364076988,0.86319507,0.622909115,1.205478572,0.533669621,DB0009110010264_,0.627978319,-0.147114576,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,86229,DB00370,10010264,73,4468,65,3598,0.604574181,0.904405473,0.636549605,1.287336165,0.747842343,DB0037010010264_,0.290563095,-0.100477487,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,86231,DB00688,10010264,128,6362,109,5269,0.843482211,0.972557085,0.745375495,1.270876387,0.920681447,DB0068810010264_,0.08264118,-0.027826506,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,86232,DB00761,10010264,315,14992,120,8505,0.000185638,1.489145499,1.200897313,1.85651592,0.001354476,DB0076110010264_,6.60434037,0.398202465,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,86237,DB00091,10010774,76,5434,22,2648,0.030234963,1.683310472,1.033110895,2.848836872,0.085202467,DB0009110010774_,2.462724888,0.520762373,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,cyclosporine,DB00091
,86239,DB01233,10010774,86,3335,58,1668,0.088927193,0.741616256,0.522534321,1.059065923,0.193481606,DB0123310010774_,1.642572832,-0.298923344,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,metoclopramide,DB01233
,86244,DB00186,10041101,70,16831,24,9984,0.018666689,1.730106879,1.073731369,2.878888622,0.058515673,DB0018610041101_,2.838460646,0.548183186,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,86247,DB00381,10041101,35,29325,34,22853,0.396003772,0.802229391,0.485750859,1.326197843,0.565642819,DB0038110041101_,0.569792462,-0.220360688,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,86250,DB00761,10041101,46,15261,20,8605,0.370358594,1.296868859,0.75138658,2.316025564,0.540012667,DB0076110041101_,0.616162682,0.259952789,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,86297,DB01175,10030095,54,10670,22,4870,0.711208484,1.120291237,0.670057494,1.934172396,0.827814237,DB0117510030095_,0.188966502,0.113588685,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,86300,DB00982,10042464,24,3340,31,2070,0.00773069,0.47987372,0.268699794,0.847398311,0.028993533,DB0098210042464_,3.540682459,-0.734232292,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,isotretinoin,DB00982
,86305,DB00542,10011906,48,1638,59,1365,0.060186223,0.678059167,0.450116873,1.016978034,0.143817715,DB0054210011906_,1.93920865,-0.388520729,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,benazepril,DB00542
,86306,DB01026,10011906,20,1090,59,1009,2.97330934268283e-06,0.313947682,0.177715322,0.533513643,3.75918403426735e-05,DB0102610011906_,10.18872354,-1.158528924,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ketoconazole,DB01026
,86307,DB01069,10011906,299,6401,182,2213,1.41179727895847e-08,0.568034515,0.467761113,0.691207729,3.06433455635205e-07,DB0106910011906_,14.99826522,-0.565573096,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,86330,DB06700,10047899,57,2168,10,608,0.229142345,1.598258081,0.802788011,3.532355172,0.384881241,DB0670010047899_,0.954820456,0.468914337,NA,10047899,Weight increased,10022891,Investigations,Inv,desvenlafaxine,DB06700
,86336,DB00181,10024855,87,9769,56,5815,0.664572171,0.924769476,0.652396384,1.32011483,0.795843536,DB0018110024855_,0.228352676,-0.078210788,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,86337,DB00273,10024855,86,8395,14,2179,0.107323919,1.594354224,0.898375144,3.044299777,0.222144202,DB0027310024855_,1.504428549,0.466468779,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,86338,DB00181,10027599,104,9752,24,5847,5.6103096197287e-06,2.597992635,1.652003022,4.241256661,6.53810633360979e-05,DB0018110027599_,9.635277893,0.954739083,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,86339,DB00273,10028334,121,8360,21,2172,0.094301256,1.496926485,0.933991267,2.511932181,0.202244493,DB0027310028334_,1.598277954,0.403413996,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,topiramate,DB00273
,86340,DB00273,10033295,98,8383,21,2172,0.494147252,1.20909113,0.746899497,2.045198386,0.656739251,DB0027310033295_,0.420468218,0.189868945,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,topiramate,DB00273
,86345,DB06643,10062237,47,52374,16,7499,0.006202191,0.420578609,0.234065751,0.795111498,0.024301197,DB0664310062237_,3.717229675,-0.866123876,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,denosumab,DB06643
,86347,DB00820,10039710,87,11828,10,5806,3.37276903186954e-07,4.269768695,2.212349951,9.226074714,5.43218345604723e-06,DB0082010039710_,12.1231694,1.451559656,female,10039710,Scleroderma,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,86348,DB00413,10011906,67,2132,72,1135,6.0063374124394e-05,0.49549135,0.347020483,0.706706706,0.000516274,DB0041310011906_,7.568872991,-0.702205383,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pramipexole,DB00413
,86349,DB00734,10011906,115,3935,94,4808,0.004808151,1.49473639,1.12437854,1.991218,0.019835557,DB0073410011906_,3.920279128,0.401949864,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,86372,DB00186,10029223,47,16854,17,9991,0.091863522,1.638880287,0.92317254,3.046288348,0.198221293,DB0018610029223_,1.618371232,0.494013257,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,86373,DB00316,10029223,171,65303,70,36883,0.02245227,1.379716405,1.038555715,1.849723159,0.067616626,DB0031610029223_,2.693901382,0.321877975,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,86378,DB00476,10029223,67,17190,31,6146,0.250450137,0.772740808,0.497179027,1.225351884,0.410199199,DB0047610029223_,0.891112386,-0.257811593,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,86387,DB01068,10029223,45,13718,17,6823,0.417708656,1.316605763,0.738224884,2.455521854,0.586748079,DB0106810029223_,0.533159718,0.275057033,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,86393,DB00734,10046571,57,3993,12,4890,1.87257804558463e-10,5.815462178,3.080381123,11.92925806,5.86309874070184e-09,DB0073410046571_,18.95458758,1.760520263,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,risperidone,DB00734
,86394,DB09020,10046571,97,1857,47,1557,0.002061542,1.730154746,1.200576811,2.523088526,0.009969208,DB0902010046571_,4.608254159,0.548210853,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,bisacodyl,DB09020
,86433,DB01225,10054889,20,5024,49,4591,0.000139387,0.37302114,0.209692841,0.640371035,0.001059055,DB0122510054889_,6.850378653,-0.986120185,NA,10054889,Transaminases increased,10022891,Investigations,Inv,enoxaparin,DB01225
,86438,DB00335,10013950,63,8403,39,5426,0.919007562,1.043089803,0.687711346,1.599873929,0.964244331,DB0033510013950_,0.036410561,0.042187273,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,86439,DB00758,10013950,64,8236,60,10014,0.148832223,1.296913654,0.896379996,1.878618183,0.282369001,DB0075810013950_,1.264540548,0.25998733,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,86440,DB00761,10013950,107,15200,55,8570,0.622646564,1.096885044,0.784260439,1.549075829,0.762835998,DB0076110013950_,0.270712214,0.092474384,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,86444,DB00425,10014625,56,12639,31,7453,0.82464109,1.065236342,0.674382441,1.711014479,0.907111606,DB0042510014625_,0.097489786,0.063196692,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,86445,DB00761,10014625,71,15236,37,8588,0.763486993,1.081632151,0.716379121,1.65738576,0.869056626,DB0076110014625_,0.140346993,0.078471151,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,86446,DB01224,10014625,65,8043,24,5893,0.00348264,1.984256525,1.223705217,3.31844451,0.0152645,DB0122410014625_,4.182225437,0.685244297,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,86451,DB00451,10017822,52,47219,11,15408,0.240814181,1.54250324,0.794883121,3.279453374,0.398846319,DB0045110017822_,0.919179102,0.433406577,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,86459,DB00186,10017955,99,16802,69,9939,0.298847616,0.848738135,0.617203094,1.172741805,0.464805301,DB0018610017955_,0.766136669,-0.164004579,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,86460,DB00999,10017955,113,21317,142,12097,3.27403299860102e-10,0.451592336,0.349219243,0.582909675,9.89171923772734e-09,DB0099910017955_,18.43156787,-0.794975418,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,86462,DB01275,10017955,58,3921,54,3295,0.633056143,0.902608068,0.610326993,1.336754641,0.771750551,DB0127510017955_,0.259093901,-0.102466853,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,hydralazine,DB01275
,86469,DB00722,10058467,33,25370,28,26004,0.522323155,1.20801768,0.707619277,2.075668063,0.680961055,DB0072210058467_,0.384250162,0.188980735,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lisinopril,DB00722
,86483,DB01156,10006451,114,13508,18,6310,2.0265023531284e-06,2.958365935,1.788217785,5.17494697,2.68008122525685e-05,DB0115610006451_,10.52707836,1.084637067,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,bupropion,DB01156
,86493,DB00425,10033318,48,12647,22,7462,0.385883991,1.287309502,0.7614886,2.241145496,0.556037646,DB0042510033318_,0.586919279,0.252554383,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,zolpidem,DB00425
,86494,DB00563,10033318,42,46604,20,15328,0.184864204,0.690692257,0.396405042,1.24222788,0.329982384,DB0056310033318_,1.108716009,-0.370060913,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,methotrexate,DB00563
,86496,DB00656,10033318,49,11964,12,6607,0.010289957,2.254892914,1.18099584,4.661700573,0.036400177,DB0065610033318_,3.313181654,0.813102483,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,trazodone,DB00656
,86497,DB01068,10033318,55,13708,21,6819,0.330849048,1.302864608,0.774527623,2.270154819,0.499532841,DB0106810033318_,0.694081936,0.264565384,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,clonazepam,DB01068
,86501,DB00598,10035664,50,1538,42,986,0.231843992,0.763298452,0.49213891,1.188895633,0.388122262,DB0059810035664_,0.946434881,-0.270106168,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,labetalol,DB00598
,86502,DB06674,10035664,62,4444,21,1469,0.898682078,0.975936247,0.584267726,1.691891522,0.95647837,DB0667410035664_,0.044497104,-0.024358016,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,golimumab,DB06674
,86507,DB00996,10063829,52,38901,18,22407,0.06291117,1.663988045,0.957207748,3.023279446,0.148801664,DB0099610063829_,1.905140975,0.509217158,NA,10063829,Device malfunction,10077536,Product issues,Prod,gabapentin,DB00996
,86511,DB00563,10073317,173,46473,49,15299,0.391632627,1.16227885,0.841484386,1.631457504,0.561489274,DB0056310073317_,0.577162607,0.150382604,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,86514,DB00996,10073317,54,38899,22,22403,0.190389281,1.413632192,0.84635404,2.438306193,0.337074883,DB0099610073317_,1.087450169,0.346162414,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,86516,DB06674,10073317,72,4434,31,1459,0.20784264,0.764277699,0.49287128,1.210247633,0.3586976,DB0667410073317_,1.025275585,-0.268824076,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,golimumab,DB06674
,86518,DB00264,10001480,74,29533,77,24815,0.191627795,0.807515965,0.578603077,1.126287098,0.338651735,DB0026410001480_,1.08278303,-0.213792453,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,86519,DB00497,10001480,35,19232,28,16347,0.899481776,1.062502273,0.627658823,1.814051119,0.95650451,DB0049710001480_,0.044469774,0.060626761,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,86522,DB01268,10001480,51,2092,105,3025,0.046726327,0.702381386,0.490129651,0.995551476,0.11894262,DB0126810001480_,2.129114086,-0.353278737,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,sunitinib,DB01268
,86524,DB00264,10013774,82,29525,21,24871,1.40195002703458e-07,3.289075249,2.016145901,5.596513548,2.46820204022799e-06,DB0026410013774_,12.91202059,1.190606446,female,10013774,Dry eye,10015919,Eye disorders,Eye,metoprolol,DB00264
,86529,DB00264,10013781,174,29433,95,24797,0.000710813,1.543070496,1.194212062,2.004113199,0.004146412,DB0026410013781_,5.485511945,0.43377426,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,86531,DB11089,10013781,69,10106,33,8374,0.009291435,1.732508618,1.127253855,2.711462093,0.033556661,DB1108910013781_,3.39451989,0.549570427,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,86532,DB00497,10013786,76,19191,55,16320,0.380764281,1.175090391,0.81916066,1.695152066,0.550802494,DB0049710013786_,0.596378984,0.161345073,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,86540,DB00497,10042128,118,19149,72,16303,0.02835404,1.395295097,1.031284383,1.898920132,0.081062207,DB0049710042128_,2.512538429,0.333105932,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,86547,DB00374,10015150,168,17548,45,5679,0.297486153,1.208191706,0.863589235,1.720954167,0.463407598,DB0037410015150_,0.769148272,0.189124784,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,treprostinil,DB00374
,86560,DB10631,10012735,82,1214,13,198,1,1.028752204,0.556088876,2.053013581,1,DB1063110012735_,0,0.028346616,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cranberry,DB10631
,86562,DB00950,10053762,139,4579,54,2002,0.525213343,1.125395684,0.812384513,1.578143323,0.683325879,DB0095010053762_,0.380783405,0.118134693,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,fexofenadine,DB00950
,86574,DB00316,10018627,83,65391,110,36843,4.41072044724345e-09,0.425130389,0.315702856,0.570637062,1.07347950884994e-07,DB0031610018627_,16.0471904,-0.855359359,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,86589,DB00016,10048959,58,2704,28,2262,0.016338692,1.732644391,1.081451237,2.835886794,0.052680795,DB0001610048959_,2.94350432,0.549648791,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,86590,DB00433,10048959,114,7542,86,5934,0.829637574,1.042963331,0.77969596,1.399426488,0.910634524,DB0043310048959_,0.093613644,0.042066019,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,86592,DB00829,10048959,100,7952,32,4422,0.005956178,1.737699436,1.154477802,2.679593363,0.023530192,DB0082910048959_,3.749470908,0.552562075,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,86596,DB00222,10018484,36,3170,23,3105,0.117411132,1.533013318,0.881620543,2.7164432,0.237295883,DB0022210018484_,1.438447466,0.427235287,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,glimepiride,DB00222
,86599,DB00213,10020646,34,18861,61,13360,9.14984681771564e-06,0.394822084,0.251471582,0.610649177,0.000100534,DB0021310020646_,9.205015348,-0.929320036,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,86602,DB01076,10020646,47,25700,101,25482,7.13907559403873e-06,0.461408273,0.319097843,0.658745299,8.08142127430267e-05,DB0107610020646_,9.423357708,-0.773472003,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,86604,DB01076,10021036,82,25665,91,25492,0.493439478,0.89502719,0.655527316,1.220410739,0.656113754,DB0107610021036_,0.421421099,-0.110901181,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,86608,DB00722,10061481,43,25360,37,25995,0.502222338,1.191256335,0.749389596,1.901948166,0.66352747,DB0072210061481_,0.410185025,0.175008494,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,86610,DB00996,10061481,36,38917,14,22411,0.241217903,1.480790503,0.779216477,2.972739465,0.399358334,DB0099610061481_,0.917896185,0.392576069,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,86612,DB01076,10061481,37,25710,19,25564,0.022207014,1.936274676,1.085035582,3.565539046,0.067089405,DB0107610061481_,2.70172914,0.660765857,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,86616,DB01590,10025482,123,4615,73,2794,0.940535843,1.020084528,0.754400951,1.387544332,0.979825795,DB0159010025482_,0.020380483,0.019885495,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,86622,DB00682,10013395,33,19426,25,16339,0.792210171,1.110205087,0.64013001,1.948404071,0.88743507,DB0068210013395_,0.119419921,0.104544761,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,86636,DB00722,10003553,136,25267,44,25988,1.14217565389475e-12,3.179224841,2.246514221,4.576654393,5.10579711949378e-11,DB0072210003553_,23.69805944,1.156637406,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,86637,DB00999,10003553,146,21284,22,12217,1.6174698105861e-11,3.809145307,2.421297555,6.269368329,5.9503420533598e-10,DB0099910003553_,21.24240222,1.337404835,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,86640,DB01222,10005750,89,9185,28,5377,0.003712231,1.860697342,1.203075167,2.960123372,0.016057927,DB0122210005750_,4.131552685,0.620951332,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,budesonide,DB01222
,86659,DB00722,10029223,71,25332,39,25993,0.001550952,1.867981494,1.246134499,2.837247401,0.007902837,DB0072210029223_,4.84053348,0.624858433,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,86660,DB00999,10029223,55,21375,20,12219,0.092247847,1.572014827,0.92674267,2.770521537,0.19882208,DB0099910029223_,1.615344927,0.452358126,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,86663,DB00471,10030124,139,14050,40,5425,0.111230706,1.341719195,0.936448677,1.961131614,0.227908532,DB0047110030124_,1.478810904,0.293951773,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,86664,DB00476,10030124,118,17139,38,6139,0.648500182,1.112264513,0.764786347,1.650351255,0.783446043,DB0047610030124_,0.244053086,0.106398039,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,86669,DB00480,10039203,86,67342,78,67584,0.53268678,1.106519711,0.804761459,1.523465331,0.689482802,DB0048010039203_,0.371813524,0.101219694,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,86694,DB01076,10001488,21,25726,73,25510,3.80440490877307e-08,0.285290545,0.166664963,0.468948764,7.53002884240212e-07,DB0107610001488_,14.09919678,-1.254247163,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,86713,DB00451,10013395,83,47188,42,15377,0.02213844,0.643980095,0.438950007,0.957446695,0.066943791,DB0045110013395_,2.703901957,-0.440087461,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,86714,DB00695,10013395,59,27990,47,20481,0.694257933,0.918551429,0.615264434,1.378118478,0.815943204,DB0069510013395_,0.203410529,-0.084957383,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,86718,DB01076,10013395,33,25714,57,25526,0.011161703,0.574724335,0.362401021,0.897942671,0.03885899,DB0107610013395_,3.247815839,-0.55386477,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,86720,DB00654,10016322,46,3770,22,2576,0.174634405,1.428618092,0.839743107,2.500037667,0.316963494,DB0065410016322_,1.148968672,0.356707608,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,86721,DB00706,10016322,10,1065,153,15772,1,0.967935473,0.453617142,1.836302637,1,DB0070610016322_,0,-0.032589854,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,86722,DB00814,10016322,152,8135,49,3366,0.137449562,1.283469082,0.921987615,1.814013108,0.266150631,DB0081410016322_,1.323692848,0.249566632,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,86726,DB00695,10019304,78,27971,34,20494,0.012439234,1.680848747,1.10955885,2.595257268,0.042355757,DB0069510019304_,3.161650921,0.519298872,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,furosemide,DB00695
,86728,DB00722,10019304,41,25362,36,25996,0.568787773,1.167354129,0.727505299,1.88055337,0.719781744,DB0072210019304_,0.328807246,0.154739759,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,lisinopril,DB00722
,86732,DB06228,10015926,39,15873,31,16045,0.339903036,1.271684165,0.772808618,2.109103438,0.509065343,DB0622810015926_,0.675178895,0.240342136,NA,10015926,Eye haemorrhage,10015919,Eye disorders,Eye,rivaroxaban,DB06228
,86733,DB00060,10003988,136,9372,33,2432,0.774632334,1.069406191,0.724443288,1.6199914,0.87716579,DB0006010003988_,0.131059263,0.067103532,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,86739,DB06228,10052535,24,15888,31,16045,0.418690426,0.781851759,0.438871939,1.376985049,0.587716101,DB0622810052535_,0.531511268,-0.246090123,NA,10052535,Small intestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,86745,DB00186,10055798,48,16853,37,9971,0.260812576,0.767563454,0.489145356,1.21309201,0.422303173,DB0018610055798_,0.862031804,-0.264534127,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,lorazepam,DB00186
,86747,DB00999,10055798,69,21361,47,12192,0.384236203,0.837936681,0.569680417,1.241979351,0.554270976,DB0099910055798_,0.590101585,-0.176812741,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,hydrochlorothiazide,DB00999
,86774,DB00019,10016173,104,18908,52,9477,1,1.002432754,0.711211597,1.428025708,1,DB0001910016173_,0,0.002429799,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,86775,DB01229,10016173,61,5680,35,2674,0.379063933,0.820530796,0.531412779,1.28468744,0.549084949,DB0122910016173_,0.599502115,-0.197803836,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,paclitaxel,DB01229
,86776,DB00019,10033775,59,18953,13,9516,0.005531,2.278632549,1.234774807,4.531247014,0.022177155,DB0001910033775_,3.808692581,0.823575504,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,pegfilgrastim,DB00019
,86777,DB00958,10033775,55,4539,22,2563,0.190116102,1.41159015,0.844506837,2.436953394,0.336715972,DB0095810033775_,1.088515518,0.344716835,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,carboplatin,DB00958
,86778,DB01229,10033775,80,5661,14,2695,0.000206267,2.720106334,1.526886691,5.207705197,0.001478115,DB0122910033775_,6.516987666,1.000670973,female,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,paclitaxel,DB01229
,86780,DB00641,10049848,106,14018,96,12379,0.887544401,0.975060982,0.731919971,1.300306676,0.953356575,DB0064110049848_,0.047766285,-0.025255265,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,86783,DB00451,10002948,93,47178,27,15392,0.671532131,1.123759676,0.725087385,1.795534619,0.800722294,DB0045110002948_,0.222241091,0.116679917,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,86796,DB00482,10047895,131,8128,57,3014,0.321221044,0.852261128,0.617980536,1.188024203,0.489508951,DB0048210047895_,0.714352531,-0.159862311,NA,10047895,Weight decreased,10022891,Investigations,Inv,celecoxib,DB00482
,86798,DB00921,10037087,133,5712,62,4841,8.28769527665782e-05,1.817952224,1.331571141,2.505195276,0.000679694,DB0092110037087_,7.293867203,0.597710716,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,buprenorphine,DB00921
,86799,DB00864,10054112,106,6763,140,8252,0.561379175,0.92382404,0.709414476,1.200183341,0.713805322,DB0086410054112_,0.337145012,-0.079233658,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,tacrolimus,DB00864
,86803,DB00060,10017944,44,9464,14,2451,0.514797066,0.813956511,0.436928133,1.610994484,0.674649293,DB0006010017944_,0.393562289,-0.205848341,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,interferon beta-1a,DB00060
,86804,DB00060,10061428,47,9461,11,2454,0.871336648,1.108253029,0.565489974,2.373168249,0.943231835,DB0006010061428_,0.058443178,0.102784928,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,interferon beta-1a,DB00060
,86805,DB08896,10012174,71,752,74,966,0.257590336,1.232350801,0.864472286,1.755857624,0.418443663,DB0889610012174_,0.871213015,0.208923565,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,regorafenib,DB08896
,86809,DB00788,10047340,41,9315,22,5039,1,1.008143766,0.585878642,1.779102649,1,DB0078810047340_,0,0.008110785,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,naproxen,DB00788
,86810,DB05676,10047340,60,47069,31,25298,0.91270678,1.040258633,0.663389836,1.661148611,0.960849796,DB0567610047340_,0.039937182,0.039469367,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,apremilast,DB05676
,86817,DB00005,10038063,63,128019,19,42400,0.799020938,1.098190963,0.648748156,1.943202593,0.891437409,DB0000510038063_,0.114920052,0.093664247,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,86818,DB00575,10061422,25,5219,32,3797,0.042673543,0.568434757,0.322348339,0.991778876,0.11105684,DB0057510061422_,2.197713138,-0.564868736,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,clonidine,DB00575
,86821,DB00682,10014080,32,19427,40,16324,0.09807552,0.672233725,0.408536815,1.097993936,0.207955072,DB0068210014080_,1.570433223,-0.397149194,NA,10014080,Ecchymosis,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,86822,DB00402,10022437,69,1283,28,668,0.323026889,1.282913309,0.806796757,2.089042701,0.49144885,DB0040210022437_,0.710397415,0.249133515,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,eszopiclone,DB00402
,86828,DB01261,10061024,35,3746,25,3278,0.516241316,1.225057444,0.71087656,2.140074278,0.675921593,DB0126110061024_,0.391678196,0.202987736,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,sitagliptin,DB01261
,86830,DB06674,10033425,72,4434,15,1475,0.104961251,1.596580955,0.903353224,3.008826314,0.218475331,DB0667410033425_,1.52108217,0.46786444,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,golimumab,DB06674
,86836,DB01068,10013911,49,13714,17,6823,0.238687484,1.434006942,0.810790203,2.657868538,0.396392387,DB0106810013911_,0.925350682,0.360472583,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,86837,DB00190,10047895,86,3211,96,4578,0.109903725,1.277158321,0.939967681,1.732987162,0.225953806,DB0019010047895_,1.487424699,0.244637548,NA,10047895,Weight decreased,10022891,Investigations,Inv,carbidopa,DB00190
,86843,DB00820,10028411,400,11515,134,5682,9.90714796891369e-05,1.472935001,1.204967262,1.809634524,0.000790677,DB0082010028411_,7.142621346,0.387257009,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,86846,DB00364,10003988,70,2680,25,1375,0.12588495,1.436449345,0.893527186,2.378904924,0.24988903,DB0036410003988_,1.386738339,0.362174336,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sucralfate,DB00364
,86847,DB00472,10003988,160,10599,43,4269,0.018796529,1.498703816,1.06212932,2.154672418,0.058845494,DB0047210003988_,2.832840021,0.404600612,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fluoxetine,DB00472
,86848,DB00620,10003988,100,4728,55,3077,0.36115663,1.183222525,0.840302192,1.681097822,0.531062182,DB0062010003988_,0.632876161,0.168241669,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,triamcinolone,DB00620
,86852,DB00381,10007739,141,29219,81,22806,0.029920323,1.358672712,1.025987219,1.809422289,0.084537859,DB0038110007739_,2.470555809,0.306508276,NA,10007739,Cataract,10015919,Eye disorders,Eye,amlodipine,DB00381
,86860,DB14500,10007739,41,7768,18,4055,0.584950701,1.188991785,0.666983995,2.201830941,0.732568728,DB1450010007739_,0.311198116,0.173105708,NA,10007739,Cataract,10015919,Eye disorders,Eye,potassium,DB14500
,86862,DB00472,10015090,33,10726,22,4290,0.072145501,0.599966493,0.338996288,1.081524646,0.165032025,DB0047210015090_,1.80161573,-0.510881471,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,86863,DB01156,10015090,31,13591,24,6304,0.060412852,0.599132517,0.340022717,1.067783352,0.144182304,DB0115610015090_,1.936676779,-0.512272475,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,86879,DB00620,10016173,110,4718,68,3064,0.816017845,1.05054411,0.766654359,1.448297161,0.901368442,DB0062010016173_,0.10384118,0.04930823,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,triamcinolone,DB00620
,86880,DB01190,10016173,69,4865,30,2255,0.828270201,1.066074072,0.682819938,1.700839358,0.909705926,DB0119010016173_,0.09463389,0.06398281,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,clindamycin,DB01190
,86883,DB11750,10016173,30,2470,23,1490,0.394948908,0.786894013,0.440064234,1.424284107,0.564826685,DB1175010016173_,0.571236348,-0.239661712,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,clobetasol,DB11750
,86884,DB00051,10017955,54,25677,40,11380,0.018157334,0.598326616,0.38996244,0.924913069,0.057250107,DB0005110017955_,2.860325761,-0.513618494,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,86885,DB00364,10017955,46,2704,51,1349,0.000122053,0.450067124,0.293737849,0.687921125,0.00094622,DB0036410017955_,6.963035898,-0.798358544,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,sucralfate,DB00364
,86886,DB00472,10017955,37,10722,26,4286,0.035037587,0.568897594,0.334834808,0.979732341,0.095469358,DB0047210017955_,2.348949943,-0.564054836,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,86888,DB01156,10017955,34,13588,42,6286,3.13106827450606e-05,0.374516683,0.230868839,0.603619495,0.000294508,DB0115610017955_,8.130205982,-0.982118929,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,86894,DB01190,10037153,41,4893,11,2274,0.133454668,1.732115758,0.87239256,3.743578973,0.260611797,DB0119010037153_,1.344723347,0.549343643,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,clindamycin,DB01190
,86897,DB11750,10037153,410,2090,239,1274,0.62679953,1.045700282,0.875849496,1.250273881,0.766281047,DB1175010037153_,0.266206274,0.044686788,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,clobetasol,DB11750
,86898,DB14500,10037153,46,7763,9,4064,0.004133346,2.675525385,1.292286813,6.223578031,0.017546028,DB1450010037153_,4.042927658,0.984145767,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,potassium,DB14500
,86942,DB00051,10003285,129,25602,40,11380,0.045219586,1.433523765,0.997649675,2.099996884,0.116000276,DB0005110003285_,2.154162708,0.360135585,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,86943,DB00425,10003285,31,12664,25,7459,0.268095475,0.730382762,0.416987558,1.291237791,0.430528444,DB0042510003285_,0.842741885,-0.31418655,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,86946,DB00761,10003285,73,15234,15,8610,0.00012761,2.75045167,1.562243107,5.165795638,0.000982493,DB0076110003285_,6.925417213,1.011765142,female,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,86949,DB00887,10003239,62,2279,23,1792,0.001837308,2.119230587,1.288514048,3.599213557,0.009075131,DB0088710003239_,4.702217499,0.751053092,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,bumetanide,DB00887
,86950,DB01039,10003239,83,2890,49,3002,0.00196475,1.75934673,1.216480372,2.568075958,0.009594697,DB0103910003239_,4.64654474,0.564942564,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fenofibrate,DB01039
,86951,DB00213,10028411,213,18682,100,13321,0.000526854,1.518753155,1.190748104,1.948010495,0.00322242,DB0021310028411_,5.737622635,0.417889706,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,86952,DB00887,10028411,51,2290,28,1787,0.16897537,1.421231626,0.875350459,2.351001221,0.309468625,DB0088710028411_,1.172898566,0.351523838,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,bumetanide,DB00887
,86953,DB01611,10028411,131,11782,22,2339,0.513268455,1.182101601,0.746821211,1.955351356,0.673250229,DB0161110028411_,0.395638207,0.167293872,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,86956,DB00381,10029223,61,29299,30,22857,0.043990618,1.586245977,1.008304842,2.545192021,0.113584813,DB0038110029223_,2.175205466,0.461370204,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,86957,DB00695,10029223,56,27993,27,20501,0.075819619,1.518957912,0.943128725,2.502123981,0.171183532,DB0069510029223_,1.765019012,0.418024515,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,86965,DB00264,10017918,58,29549,34,24858,0.094912337,1.435055639,0.923685912,2.261228141,0.20306628,DB0026410017918_,1.594222849,0.361203621,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,metoprolol,DB00264
,86969,DB00480,10002544,63,67365,23,67639,1.21863623143447e-05,2.750396461,1.681810998,4.647739339,0.000129109,DB0048010002544_,8.954856345,1.011745069,female,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,86971,DB00480,10040865,57,67371,10,67652,2.21423667996291e-09,5.723565049,2.896710784,12.57283729,5.72846566267963e-08,DB0048010040865_,16.67523302,1.744591872,female,10040865,Skin hyperpigmentation,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,86972,DB00476,10020937,279,16978,87,6090,0.281770479,1.150302071,0.899458208,1.483361931,0.4457755,DB0047610020937_,0.807939817,0.140024578,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,86973,DB00820,10020937,78,11837,46,5770,0.337040843,0.826577796,0.566115877,1.218985921,0.506177498,DB0082010020937_,0.680867885,-0.190461239,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,86979,DB00787,10013700,151,16849,79,17169,1.1260201159011e-06,1.947644605,1.472668285,2.5924616,1.58924406973455e-05,DB0078710013700_,11.04966699,0.666620747,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,acyclovir,DB00787
,86988,DB00581,10001946,48,2065,40,2029,0.453178894,1.179032302,0.755126916,1.849653559,0.62075637,DB0058110001946_,0.476816592,0.164694019,NA,10001946,Ammonia increased,10022891,Investigations,Inv,lactulose,DB00581
,86999,DB00374,10001760,56,17660,9,5715,0.058676329,2.013430095,0.987649707,4.633673606,0.141023848,DB0037410001760_,1.958826265,0.699839783,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,treprostinil,DB00374
,87000,DB00196,10033661,38,5045,77,3208,1.82431672371635e-09,0.313853634,0.206444168,0.469999167,4.80001652481323e-08,DB0019610033661_,16.85206138,-1.158828537,male,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,fluconazole,DB00196
,87001,DB00741,10033661,18,4076,46,3128,5.7987438940093e-06,0.300342797,0.163554932,0.529334929,6.72638937572968e-05,DB0074110033661_,9.606886962,-1.202830801,male,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,hydrocortisone,DB00741
,87002,DB01050,10033661,51,18057,27,9344,0.90538312,0.977433712,0.601123879,1.622281309,0.957832006,DB0105010033661_,0.043082876,-0.022824803,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,ibuprofen,DB01050
,87015,DB00341,10033295,47,11358,27,5041,0.312455241,0.772576186,0.470805535,1.291622082,0.479934902,DB0034110033295_,0.734104805,-0.258024652,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,87016,DB00471,10033295,47,14142,20,5445,0.683926375,0.904815642,0.525227094,1.613594372,0.808956803,DB0047110033295_,0.212009759,-0.100024067,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,87020,DB01076,10043607,183,25564,202,25381,0.306608298,0.899457626,0.731761853,1.104990336,0.47363869,DB0107610043607_,0.747310506,-0.105963335,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,atorvastatin,DB01076
,87022,DB00005,10067484,365,127717,89,42330,0.008993418,1.359238565,1.075068238,1.73399309,0.032710523,DB0000510067484_,3.42005845,0.306924664,NA,10067484,Adverse reaction,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,87034,DB00334,10061920,33,2816,55,2757,0.017727071,0.587487358,0.368322445,0.924108184,0.056213786,DB0033410061920_,2.878593254,-0.531900552,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,87036,DB01270,10005169,51,1207,28,941,0.165446598,1.419800406,0.870847584,2.357796336,0.30471666,DB0127010005169_,1.188372916,0.350516302,NA,10005169,Blindness,10015919,Eye disorders,Eye,ranibizumab,DB01270
,87037,DB01263,10013709,26,598,57,808,0.051277955,0.61651583,0.367473634,1.010260338,0.127407226,DB0126310013709_,2.060366817,-0.48367128,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,posaconazole,DB01263
,87046,DB01240,10061905,58,5693,21,1555,0.27146658,0.754425002,0.449365032,1.312983147,0.434270528,DB0124010061905_,0.834087602,-0.281799407,NA,10061905,Paracentesis,10022891,Investigations,Inv,epoprostenol,DB01240
,87066,DB00169,10005169,69,38622,27,18148,0.445520251,1.200802888,0.759127351,1.950235519,0.613446516,DB0016910005169_,0.488662198,0.182990406,NA,10005169,Blindness,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,87068,DB00169,10011732,45,38646,18,18157,0.685236134,1.174556541,0.666282994,2.156611308,0.809887557,DB0016910011732_,0.210859859,0.160890665,NA,10011732,Cyst,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,87072,DB00169,10025409,38,38653,14,18161,0.551884355,1.275256186,0.675237944,2.548941182,0.70578151,DB0016910025409_,0.348449565,0.243147089,NA,10025409,Macular degeneration,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,87078,DB00169,10069889,34,38657,16,18159,1,0.998211866,0.535997443,1.937129126,1,DB0016910069889_,0,-0.001789735,NA,10069889,Product adhesion issue,10077536,Product issues,Prod,cholecalciferol,DB00169
,87088,DB13867,10010774,99,4451,51,2503,0.667498386,1.091609489,0.768054637,1.5676796,0.798071144,DB1386710010774_,0.225557532,0.087653203,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,fluticasone,DB13867
,87093,DB13867,10022437,69,4481,29,2525,0.204146849,1.340665293,0.854554525,2.15229392,0.354027837,DB1386710022437_,1.038379732,0.293165978,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,fluticasone,DB13867
,87094,DB13867,10028334,72,4478,29,2525,0.143698663,1.399884554,0.895259865,2.241444555,0.275099734,DB1386710028334_,1.290621577,0.336389772,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone,DB13867
,87095,DB13867,10028411,47,4503,23,2531,0.619126423,1.148578431,0.681738323,1.986703822,0.75999337,DB1386710028411_,0.27444557,0.138525031,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone,DB13867
,87096,DB13867,10047899,90,4460,33,2521,0.036733261,1.541493575,1.020556299,2.379365612,0.099034183,DB1386710047899_,2.312290209,0.4327518,NA,10047899,Weight increased,10022891,Investigations,Inv,fluticasone,DB13867
,87100,DB00153,10043607,47,7376,34,3405,0.054420097,0.638161896,0.400980554,1.025244426,0.133299064,DB0015310043607_,2.015160073,-0.449163272,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,ergocalciferol,DB00153
,87128,DB00722,10012373,20,25383,32,26000,0.127628208,0.640200992,0.346906857,1.154573043,0.25229055,DB0072210012373_,1.377173881,-0.445973102,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,87130,DB00451,10013887,88,47183,32,15387,0.596287139,0.896799931,0.591944208,1.39007102,0.74169581,DB0045110013887_,0.298816079,-0.108922485,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,87133,DB00451,10028347,58,47213,15,15404,0.497241692,1.261549367,0.705453937,2.397564094,0.659401538,DB0045110028347_,0.416422616,0.232340622,NA,10028347,Muscle twitching,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,87134,DB00476,10028347,59,17198,15,6162,0.29003292,1.409250312,0.788649207,2.677095334,0.45525755,DB0047610028347_,0.786891977,0.343057869,NA,10028347,Muscle twitching,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,87138,DB00451,10039897,63,47208,14,15405,0.233001277,1.468409608,0.813568708,2.838919292,0.389533381,DB0045110039897_,0.942805716,0.384179916,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,87139,DB00476,10039897,46,17211,25,6152,0.104604133,0.657713375,0.395343627,1.118136829,0.217921822,DB0047610039897_,1.523618896,-0.418986043,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,87140,DB00502,10039897,35,1359,42,1830,0.642032933,1.122107086,0.691474981,1.811087151,0.778567306,DB0050210039897_,0.250299836,0.115208244,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,haloperidol,DB00502
,87143,DB00476,10052904,128,17129,35,6142,0.180508003,1.311319766,0.895049845,1.966773015,0.32446508,DB0047610052904_,1.125577362,0.271034085,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,87145,DB11089,10052904,40,10135,42,8365,0.317049311,0.786069359,0.496321972,1.243279793,0.484839534,DB1108910052904_,0.723937301,-0.240710248,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,87148,DB00563,10048694,68,46578,18,15330,0.455198429,1.243350954,0.730696103,2.222621878,0.622765945,DB0056310048694_,0.473584522,0.217810117,NA,10048694,Rheumatoid nodule,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,87174,DB00005,10050031,85,127997,28,42391,1,1.005390887,0.649038923,1.601329422,1,DB0000510050031_,0,0.005376408,NA,10050031,Muscle strain,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,87183,DB00563,10061623,416,46230,84,15264,1.89176796921372e-05,1.635080262,1.289611544,2.094153813,0.000190299,DB0056310061623_,8.566914192,0.491691893,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,87185,DB00563,10062132,43,46603,7,15341,0.099495597,2.021999131,0.901618194,5.329383205,0.210099692,DB0056310062132_,1.560173137,0.704086691,NA,10062132,Tooth extraction,10042613,Surgical and medical procedures,Surg,methotrexate,DB00563
,87187,DB01268,10035664,30,2113,52,3078,0.49748822,0.840444516,0.515769321,1.347320455,0.659595353,DB0126810035664_,0.416128734,-0.173824341,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sunitinib,DB01268
,87188,DB06589,10013709,125,1905,172,2481,0.672225816,0.946483758,0.739745823,1.208380039,0.801033888,DB0658910013709_,0.221852026,-0.055001469,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pazopanib,DB06589
,87189,DB01413,10013968,38,1182,52,1607,1,0.993526751,0.631678378,1.550197372,1,DB0141310013968_,0,-0.006494292,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cefepime,DB01413
,87196,DB00695,10061309,62,27987,31,20497,0.092492136,1.464738727,0.936754662,2.333758509,0.199209751,DB0069510061309_,1.613396985,0.381676883,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,furosemide,DB00695
,87233,DB00186,10054236,73,16828,33,9975,0.226888514,1.311248733,0.857309448,2.044247786,0.382072176,DB0018610054236_,0.962145745,0.270979914,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,lorazepam,DB00186
,87234,DB00281,10054236,44,11414,19,5652,0.688547392,1.14671757,0.655021319,2.081765224,0.812273812,DB0028110054236_,0.207917789,0.136903574,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,lidocaine,DB00281
,87235,DB00537,10054236,56,7501,41,4257,0.243236588,0.775189158,0.507970704,1.191769859,0.401598032,DB0053710054236_,0.912303611,-0.254648204,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,87238,DB00761,10054236,93,15214,37,8588,0.08144885,1.418808483,0.958664224,2.138876545,0.180772019,DB0076110054236_,1.710518608,0.349817423,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,87240,DB00787,10054236,94,16906,88,17160,0.60345016,1.084203327,0.801347095,1.468122047,0.747103097,DB0078710054236_,0.291552088,0.080845456,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,acyclovir,DB00787
,87242,DB01373,10054236,79,22641,24,7357,0.819607853,1.069593582,0.669462579,1.768049241,0.903893279,DB0137310054236_,0.10104398,0.067278746,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,calcium,DB01373
,87267,DB00820,10013700,78,11837,31,5785,0.358313017,1.2296444,0.800438437,1.931760432,0.528047637,DB0082010013700_,0.638568777,0.206725022,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,tadalafil,DB00820
,87274,DB01192,10074903,45,723,46,508,0.098308406,0.687566668,0.438204834,1.078127988,0.208322836,DB0119210074903_,1.568666305,-0.374596483,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,oxymorphone,DB01192
,87275,DB00678,10005483,98,15501,94,10630,0.022178321,0.714966182,0.532618749,0.960188681,0.067033539,DB0067810005483_,2.702562207,-0.335520036,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,losartan,DB00678
,87280,DB00864,10044439,173,6696,196,8196,0.491174264,1.080372404,0.873145489,1.335835281,0.654376215,DB0086410044439_,0.42407284,0.077305801,NA,10044439,Transplant rejection,10021428,Immune system disorders,Immun,tacrolimus,DB00864
,87282,DB01015,10044439,30,9857,46,9335,0.049919604,0.617656533,0.376124549,1.000629291,0.124864118,DB0101510044439_,2.08052919,-0.481822748,NA,10044439,Transplant rejection,10021428,Immune system disorders,Immun,sulfamethoxazole,DB01015
,87284,DB01610,10044439,32,909,54,1164,0.26706088,0.758927394,0.469961741,1.208133311,0.429339157,DB0161010044439_,0.845508096,-0.275849166,NA,10044439,Transplant rejection,10021428,Immune system disorders,Immun,valganciclovir,DB01610
,87285,DB00046,10013950,33,5426,22,4670,0.416327168,1.29097241,0.729279907,2.327642923,0.585576646,DB0004610013950_,0.535158198,0.25539574,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,insulin lispro,DB00046
,87286,DB00285,10013950,65,10886,13,3705,0.089137108,1.701593019,0.927642827,3.369418516,0.193850072,DB0028510013950_,1.640670243,0.531564882,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,87292,DB01076,10027141,37,25710,39,25544,0.819262089,0.942570948,0.58438743,1.517884147,0.903663618,DB0107610027141_,0.101298092,-0.059144086,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,87297,DB05351,10047895,63,2660,28,1103,0.815803215,0.933007628,0.585284209,1.521463527,0.901247741,DB0535110047895_,0.103975097,-0.069341903,NA,10047895,Weight decreased,10022891,Investigations,Inv,dexlansoprazole,DB05351
,87298,DB01088,10048959,54,1375,10,427,0.175224246,1.676465968,0.835969389,3.725343408,0.31773787,DB0108810048959_,1.146528543,0.516687988,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,iloprost,DB01088
,87299,DB09140,10048959,234,3507,67,1731,8.13799152193935e-05,1.723706927,1.29991241,2.310935975,0.000668878,DB0914010048959_,7.309909237,0.544477162,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,87332,DB00559,10068319,90,9569,16,3290,0.013385304,1.933989129,1.126436144,3.532729059,0.044919593,DB0055910068319_,3.102881215,0.659584776,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,87333,DB00820,10068319,167,11748,38,5778,6.02751628346246e-06,2.161375069,1.509631684,3.165773049,6.95951089439099e-05,DB0082010068319_,9.572816267,0.770744625,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,87334,DB01076,10068319,160,25587,67,25516,5.67106164685645e-10,2.381531305,1.778717774,3.218442069,1.64711442417262e-08,DB0107610068319_,17.92165582,0.867743686,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,87337,DB09140,10068319,77,3664,15,1783,0.000664517,2.497676132,1.419355396,4.69048462,0.003927777,DB0914010068319_,5.539681619,0.915360752,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,87344,DB09072,10016338,51,6420,12,2523,0.122167016,1.670161335,0.876590013,3.447403256,0.244529394,DB0907210016338_,1.408419755,0.512920229,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,87345,DB01156,10029216,63,13559,17,6311,0.053243142,1.724850658,0.995887207,3.14716432,0.131094186,DB0115610029216_,2.031839241,0.545140472,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,87346,DB09072,10029216,44,6427,15,2520,0.77158328,1.150126125,0.626508481,2.229268075,0.875013656,DB0907210029216_,0.133515786,0.13987161,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,87358,DB00264,10001949,110,29497,75,24817,0.183155767,1.233959248,0.911304593,1.678570593,0.327856806,DB0026410001949_,1.115178332,0.210227901,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,87374,DB08895,10011906,243,27871,118,6528,8.58517138415376e-10,0.482338862,0.384875184,0.607235273,2.41866269916915e-08,DB0889510011906_,17.53746596,-0.729108378,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,87375,DB00043,10003239,352,6061,96,2204,0.015346179,1.333254762,1.055111657,1.697814492,0.050211438,DB0004310003239_,2.991512437,0.287623142,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,omalizumab,DB00043
,87377,DB00043,10028411,130,6283,53,2247,0.445568581,0.877237058,0.630187238,1.235970077,0.613465694,DB0004310028411_,0.488630935,-0.130978017,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,omalizumab,DB00043
,87378,DB00043,10037660,104,6309,41,2259,0.634758926,0.908250754,0.624853895,1.342003963,0.77293794,DB0004310037660_,0.257556518,-0.096234777,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,87381,DB00005,10000084,45,128037,11,42408,0.440483919,1.354957629,0.689928776,2.905390152,0.608862001,DB0000510000084_,0.496163637,0.303770184,NA,10000084,Abdominal pain lower,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,87385,DB01012,10049414,38,10594,46,8639,0.078547516,0.673664129,0.426105333,1.059373786,0.175920364,DB0101210049414_,1.737723864,-0.395023617,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,87388,DB00333,10028334,18,3053,35,3117,0.027041414,0.525122086,0.279339059,0.955045265,0.078108085,DB0033310028334_,2.549661705,-0.644124499,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,methadone,DB00333
,87392,DB01224,10013887,31,8077,31,5886,0.246059477,0.728762589,0.427918321,1.241082546,0.404988939,DB0122410013887_,0.903895524,-0.316407267,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,87404,DB00394,10011906,24,1615,35,759,2.82467511374581e-05,0.3224306,0.182095796,0.562145473,0.000269289,DB0039410011906_,8.219726589,-1.131867359,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,beclomethasone dipropionate,DB00394
,87406,DB09104,10010774,67,983,51,821,0.702814669,1.097137146,0.741492242,1.631620469,0.821701075,DB0910410010774_,0.196378605,0.092704192,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,magnesium hydroxide,DB09104
,87407,DB09104,10012735,60,990,24,848,0.001593128,2.140546204,1.299981409,3.627472884,0.008069247,DB0910410012735_,4.819695077,0.761061032,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,magnesium hydroxide,DB09104
,87412,DB00490,10005750,39,4031,11,1565,0.429148117,1.376377881,0.689175971,2.987776352,0.597655943,DB0049010005750_,0.514740037,0.319455325,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,buspirone,DB00490
,87413,DB14513,10005750,87,7090,23,3541,0.005771952,1.889070942,1.179493431,3.140746286,0.022957669,DB1451310005750_,3.774103226,0.636085143,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,magnesium,DB14513
,87441,DB01043,10011906,110,1291,151,1259,0.009330088,0.710510741,0.543711306,0.926187357,0.033666192,DB0104310011906_,3.391261148,-0.341771214,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,memantine,DB01043
,87442,DB00230,10027599,221,19453,25,8626,2.86186811190515e-14,3.920171446,2.58377159,6.194047634,1.58034040591233e-12,DB0023010027599_,27.17338085,1.366135389,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,87443,DB00196,10042128,38,5045,21,3264,0.595338209,1.170659629,0.668454836,2.103790666,0.740966183,DB0019610042128_,0.299800291,0.157567375,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,fluconazole,DB00196
,87444,DB00404,10042128,99,19793,23,9839,0.000672442,2.139621586,1.347565001,3.532698797,0.003962592,DB0040410042128_,5.530856923,0.760628984,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,87445,DB00646,10042128,50,3403,26,1974,0.719835874,1.115526721,0.678795912,1.873254253,0.834673745,DB0064610042128_,0.180714355,0.109326689,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,nystatin,DB00646
,87446,DB00641,10013952,67,14057,45,12430,0.156118006,1.316544531,0.888322356,1.967405048,0.292288264,DB0064110013952_,1.230014757,0.275010525,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,87447,DB00927,10013952,41,7456,19,4997,0.18985951,1.446176241,0.81945518,2.641429354,0.336329507,DB0092710013952_,1.089663924,0.368922998,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,87449,DB00999,10013952,117,21313,41,12198,0.006126547,1.633202263,1.134496506,2.393296518,0.024069394,DB0099910013952_,3.726814217,0.490542666,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,87450,DB06626,10013952,20,668,74,1378,0.023402962,0.557670047,0.319377546,0.933354457,0.069799938,DB0662610013952_,2.662122152,-0.583987806,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,axitinib,DB06626
,87461,DB06700,10016256,132,2093,34,584,0.771174216,1.083244452,0.728999815,1.647839409,0.874719584,DB0670010016256_,0.13385192,0.07996066,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,desvenlafaxine,DB06700
,87462,DB00563,10069327,51,46595,20,15328,0.493246559,0.838829056,0.491187784,1.485962164,0.656001425,DB0056310069327_,0.421592318,-0.175748341,NA,10069327,Product quality issue,10077536,Product issues,Prod,methotrexate,DB00563
,87477,DB00136,10046571,42,2050,21,1661,0.07438314,1.620284985,0.933948134,2.892174507,0.168817584,DB0013610046571_,1.778936534,0.482602051,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,calcitriol,DB00136
,87479,DB01390,10046571,34,1375,23,1494,0.083179839,1.605925151,0.913603899,2.870725418,0.183752748,DB0139010046571_,1.694164188,0.473700008,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,sodium bicarbonate,DB01390
,87480,DB01593,10046571,38,1095,15,683,0.152317883,1.579780267,0.841402699,3.116075676,0.287194537,DB0159310046571_,1.247595462,0.457285766,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,zinc,DB01593
,87485,DB00394,10047700,49,1590,13,781,0.054128345,1.851011267,0.981710714,3.741980714,0.132709665,DB0039410047700_,2.019591508,0.615732121,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,beclomethasone dipropionate,DB00394
,87486,DB00471,10010774,225,13964,90,5375,0.751567499,0.962295987,0.74874358,1.245506983,0.859740615,DB0047110010774_,0.151124545,-0.038433196,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,87499,DB00341,10047571,90,11315,27,5041,0.071102293,1.485033478,0.955297217,2.378706795,0.163224784,DB0034110047571_,1.812626984,0.395437316,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,cetirizine,DB00341
,87500,DB00471,10047571,89,14100,28,5437,0.407703876,1.225642381,0.792654775,1.949561282,0.577148663,DB0047110047571_,0.549655397,0.203465099,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,montelukast,DB00471
,87511,DB00126,10062237,35,10136,27,5918,0.292585177,0.756886158,0.444634371,1.301545923,0.458169336,DB0012610062237_,0.780516435,-0.278542422,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,ascorbic acid,DB00126
,87512,DB00158,10062237,43,16772,39,8065,0.004503343,0.530171547,0.335388003,0.84051186,0.018788947,DB0015810062237_,3.974486507,-0.634554651,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,folic acid,DB00158
,87515,DB13961,10062237,36,9421,27,6387,0.701132427,0.903945095,0.533100743,1.549747209,0.820482419,DB1396110062237_,0.197862796,-0.100986656,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,fish oil,DB13961
,87519,DB00497,10001053,55,19212,72,16303,0.015951162,0.6482392,0.447580885,0.934363919,0.05171462,DB0049710001053_,2.962014748,-0.433495515,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,87522,DB01075,10001053,49,19899,32,11065,0.487518252,0.851475705,0.534139282,1.374682051,0.651321114,DB0107510001053_,0.428752495,-0.160784311,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,87525,DB00316,10020578,27,65447,36,36917,0.000871747,0.423055949,0.246975307,0.716680404,0.004920305,DB0031610020578_,5.314384678,-0.86025084,NA,10020578,Hyperbilirubinaemia,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,87532,DB01234,10020578,28,31597,44,32844,0.098432345,0.661485375,0.396492914,1.086817649,0.208535036,DB0123410020578_,1.567648213,-0.413267405,NA,10020578,Hyperbilirubinaemia,10019805,Hepatobiliary disorders,Hepat,dexamethasone,DB01234
,87556,DB00019,10043554,64,18948,43,9486,0.150240892,0.745106269,0.498054927,1.12450722,0.284321383,DB0001910043554_,1.257650051,-0.294228428,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,pegfilgrastim,DB00019
,87557,DB00404,10043554,97,19795,60,9802,0.174907284,0.800559814,0.573721691,1.124833683,0.317338254,DB0040410043554_,1.147787028,-0.222444029,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,alprazolam,DB00404
,87562,DB00381,10001053,106,29254,97,22790,0.25749095,0.851325721,0.639878678,1.133684831,0.418397541,DB0038110001053_,0.871323244,-0.160960473,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,87563,DB01076,10001053,112,25635,127,25456,0.330847122,0.875734706,0.672682241,1.138781962,0.499532841,DB0107610001053_,0.694081936,-0.132692081,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,87566,DB14726,10007559,45,1972,54,2794,0.412049092,1.180650535,0.773379137,1.794938131,0.581464764,DB1472610007559_,0.542204903,0.166065587,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,dabigatran,DB14726
,87578,DB00480,10021114,39,67389,28,67634,0.180989182,1.397911643,0.838365251,2.359033965,0.325105385,DB0048010021114_,1.123605888,0.334979439,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,lenalidomide,DB00480
,87580,DB00669,10003239,121,6256,14,1083,0.176850356,1.496124513,0.854028539,2.829112207,0.319848048,DB0066910003239_,1.139909245,0.402878106,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sumatriptan,DB00669
,87581,DB00571,10046571,69,5054,12,2597,0.000201968,2.954306201,1.58407023,6.005042462,0.00145325,DB0057110046571_,6.533953124,1.083263835,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,propranolol,DB00571
,87586,DB00335,10040829,41,8425,14,5451,0.03794763,1.894710405,1.010660849,3.766612233,0.101506483,DB0033510040829_,2.287632606,0.639066006,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,atenolol,DB00335
,87589,DB00758,10040829,41,8259,22,10052,0.002083771,2.268139642,1.318641708,4.001505167,0.010061897,DB0075810040829_,4.598999608,0.818959955,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,clopidogrel,DB00758
,87590,DB00335,10040844,39,8427,17,5448,0.216791933,1.48309128,0.818593617,2.798891211,0.369593539,DB0033510040844_,0.995351422,0.394128612,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,atenolol,DB00335
,87594,DB00758,10050584,150,8150,101,9973,3.70317364010269e-06,1.817262144,1.400239422,2.366760302,4.54068443643761e-05,DB0075810050584_,9.999847707,0.597331052,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,87617,DB00046,10000891,19,5440,32,4660,0.023383508,0.508655887,0.272015469,0.926529539,0.069757747,DB0004610000891_,2.66272679,-0.675983547,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,insulin lispro,DB00046
,87638,DB00425,10044390,37,12658,19,7465,0.679433145,1.148470256,0.64320531,2.11583252,0.806070738,DB0042510044390_,0.215583777,0.138430844,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,87639,DB00451,10044390,152,47119,58,15361,0.29797478,0.854385151,0.627026731,1.177747517,0.463889168,DB0045110044390_,0.768109618,-0.15737319,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,87640,DB00678,10044390,57,15542,37,10687,0.833874416,1.059313672,0.687725457,1.649608661,0.913684982,DB0067810044390_,0.090269426,0.05762122,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,losartan,DB00678
,87644,DB00005,10044728,51,128031,32,42387,0.007097518,0.527667598,0.33262408,0.848512199,0.027082568,DB0000510044728_,3.608864995,-0.639288742,NA,10044728,Tuberculin test positive,10022891,Investigations,Inv,etanercept,DB00005
,87648,DB00207,10021789,147,8933,70,5385,0.120003436,1.265876689,0.944005226,1.711290612,0.241392402,DB0020710021789_,1.421331444,0.235764917,NA,10021789,Infection,10021881,Infections and infestations,Infec,azithromycin,DB00207
,87654,DB00169,10008111,53,38638,38,18137,0.055114435,0.65469805,0.423386765,1.021122025,0.134541021,DB0016910008111_,2.005886137,-0.423581142,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,87656,DB00758,10008111,80,8220,106,9968,0.604359326,0.915186121,0.674849436,1.237032471,0.74776807,DB0075810008111_,0.290662416,-0.088627823,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,87675,DB00563,10010774,221,46425,62,15286,0.300323843,1.173654437,0.881329218,1.582785589,0.466494044,DB0056310010774_,0.762510027,0.160122331,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,87676,DB00601,10013968,27,878,30,881,0.788140928,0.903127899,0.511934899,1.586325012,0.88522456,DB0060110013968_,0.121913926,-0.101891098,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,linezolid,DB00601
,87677,DB00601,10028813,55,850,38,873,0.070581331,1.48620051,0.954012317,2.336190705,0.162323994,DB0060110028813_,1.818160976,0.39622287,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,linezolid,DB00601
,87678,DB00601,10047700,32,873,25,886,0.349087431,1.298870011,0.73895905,2.306695586,0.518609796,DB0060110047700_,0.656603516,0.261494664,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,linezolid,DB00601
,87679,DB00331,10047924,90,24856,41,20711,0.001100449,1.829018285,1.25029414,2.715904749,0.005957226,DB0033110047924_,5.123150302,0.603779367,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,87687,DB00349,10016256,31,991,21,923,0.324895895,1.374673753,0.758862428,2.536640078,0.493335756,DB0034910016256_,0.70656529,0.318216433,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,clobazam,DB00349
,87688,DB01080,10016256,42,2017,22,2090,0.011200903,1.977857536,1.14945273,3.492240569,0.038974812,DB0108010016256_,3.244839685,0.682014206,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,vigabatrin,DB01080
,87690,DB01068,10061422,65,13698,64,6776,0.000151776,0.502402416,0.349808655,0.721870361,0.001138702,DB0106810061422_,6.777866563,-0.688353855,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,87695,DB00203,10048561,30,13848,22,8916,0.670868835,0.877981735,0.489413373,1.598412879,0.800335284,DB0020310048561_,0.222724534,-0.130129489,NA,10048561,Stent placement,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,87704,DB01203,10013709,41,658,20,485,0.145092351,1.510517577,0.852352642,2.758148269,0.277192459,DB0120310013709_,1.283043217,0.412452359,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,nadolol,DB01203
,87714,DB00005,10043431,63,128019,7,42412,0.003259416,2.981755047,1.365362729,7.718287577,0.014470693,DB0000510043431_,4.235629831,1.092512069,female,10043431,Thinking abnormal,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,87715,DB00455,10069327,54,9347,29,5089,1,1.013807899,0.633274726,1.653543862,1,DB0045510069327_,0,0.013713438,NA,10069327,Product quality issue,10077536,Product issues,Prod,loratadine,DB00455
,87744,DB00281,10003549,223,11235,110,5561,1,1.003441168,0.793170324,1.275595128,1,DB0028110003549_,0,0.003435261,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,87747,DB00196,10016288,89,4994,130,3155,1.53003851927461e-09,0.432552412,0.325286132,0.573076405,4.08917767962716e-08,DB0019610016288_,17.01233685,-0.838051777,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,fluconazole,DB00196
,87748,DB00281,10016288,87,11371,83,5588,2.49861093176889e-05,0.515111825,0.376243642,0.70572493,0.000241456,DB0028110016288_,8.328823961,-0.663371266,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,lidocaine,DB00281
,87750,DB06724,10016288,69,7860,44,3875,0.191989259,0.773160965,0.521063211,1.157875504,0.339137705,DB0672410016288_,1.081349045,-0.257268018,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,calcium carbonate,DB06724
,87753,DB11089,10016288,130,10045,149,8258,0.006327001,0.717288721,0.561484857,0.915415226,0.024709192,DB1108910016288_,3.700579965,-0.33227684,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,docusate,DB11089
,87803,DB00904,10074903,37,23032,29,14427,0.377339634,0.799201129,0.478047718,1.348000998,0.547265831,DB0090410074903_,0.602820615,-0.224142638,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,87805,DB06228,10051077,69,15843,104,15972,0.00950679,0.668875433,0.485659271,0.916299464,0.034193484,DB0622810051077_,3.375720191,-0.402157435,NA,10051077,Post procedural haemorrhage,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,87816,DB00264,10013722,33,29574,41,24851,0.102262178,0.676350099,0.414234004,1.096727471,0.214350984,DB0026410013722_,1.540140493,-0.391044439,NA,10013722,Drug level increased,10022891,Investigations,Inv,metoprolol,DB00264
,87819,DB00512,10013722,50,4687,60,5038,0.631614477,0.895756974,0.601533671,1.32888059,0.770447434,DB0051210013722_,0.26078385,-0.110086138,NA,10013722,Drug level increased,10022891,Investigations,Inv,vancomycin,DB00512
,87824,DB00813,10029354,83,10489,64,10104,0.186260488,1.249257449,0.889743437,1.761055268,0.331753815,DB0081310029354_,1.103362107,0.222549334,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,fentanyl,DB00813
,87825,DB00928,10029354,34,801,37,1249,0.139753976,1.432583989,0.864426927,2.367811246,0.269464604,DB0092810029354_,1.311318238,0.359479799,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,azacitidine,DB00928
,87826,DB00005,10050551,89,127993,11,42408,0.000720044,2.680877269,1.428070094,5.56409483,0.004191421,DB0000510050551_,5.4747154,0.98614408,NA,10050551,Lupus-like syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,87827,DB06643,10022086,299,52122,23,7492,0.002294138,1.868597862,1.220902761,2.995477544,0.010878843,DB0664310022086_,4.520935343,0.625188343,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,87828,DB06643,10041569,219,52202,13,7502,0.000670313,2.420954482,1.385619961,4.621763524,0.003953591,DB0664310041569_,5.533131098,0.884161877,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,87830,DB00814,10022086,159,8128,38,3377,0.001962324,1.738372172,1.210608526,2.552382631,0.009584654,DB0081410022086_,4.647592013,0.552949142,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,87833,DB00126,10051398,45,10126,46,5899,0.008622968,0.569943245,0.368840708,0.880112618,0.031624766,DB0012610051398_,3.453814717,-0.562218493,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ascorbic acid,DB00126
,87834,DB00019,10061313,105,18907,32,9497,0.01388178,1.648147699,1.099228756,2.533204433,0.046240347,DB0001910061313_,3.073902553,0.499652051,NA,10061313,Neutrophil count abnormal,10022891,Investigations,Inv,pegfilgrastim,DB00019
,87837,DB00108,10017944,44,10150,21,3274,0.14788988,0.67586511,0.392706057,1.198489271,0.281055997,DB0010810017944_,1.269201351,-0.391761765,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,natalizumab,DB00108
,87845,DB00904,10005555,43,23026,29,14427,0.808714072,0.929028824,0.566545116,1.543732557,0.896808395,DB0090410005555_,0.108913046,-0.073615514,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,ondansetron,DB00904
,87849,DB01306,10005555,84,4124,84,3782,0.585829888,0.917086737,0.667311443,1.26034212,0.733159006,DB0130610005555_,0.310392676,-0.086553224,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,insulin aspart,DB01306
,87868,DB00254,10038695,37,5898,37,3351,0.020439202,0.568223978,0.349612682,0.923414888,0.062865016,DB0025410038695_,2.766765458,-0.565239611,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxycycline,DB00254
,87871,DB00254,10043607,32,5903,42,3346,0.00037396,0.431907601,0.26334276,0.702233948,0.002424355,DB0025410043607_,6.022189929,-0.839543601,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,doxycycline,DB00254
,87874,DB01156,10043607,44,13578,31,6297,0.081638097,0.65825473,0.405951158,1.079385497,0.18108501,DB0115610043607_,1.708788688,-0.418163294,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,bupropion,DB01156
,87880,DB00758,10000081,95,8205,101,9973,0.386644591,1.143261664,0.853377935,1.530590309,0.556752113,DB0075810000081_,0.585635178,0.133885286,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,87887,DB11089,10020993,37,10138,46,8361,0.076405956,0.66338349,0.417952902,1.04648374,0.172163369,DB1108910020993_,1.759311432,-0.41040204,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,87893,DB11089,10063743,40,10135,17,8390,0.022782026,1.947728114,1.078493227,3.66688316,0.068374692,DB1108910063743_,2.682752517,0.666663624,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,87895,DB00758,10064355,39,8261,49,10025,0.914752716,0.965870345,0.616894003,1.503154154,0.961867192,DB0075810064355_,0.038878892,-0.034725672,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,87898,DB01076,10064355,115,25632,107,25476,0.63824431,1.068254274,0.813286843,1.404037801,0.775475613,DB0107610064355_,0.254278743,0.066025796,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,87902,DB11089,10064355,46,10129,19,8388,0.011947495,2.004812632,1.150714268,3.626591974,0.041010762,DB1108910064355_,3.193920748,0.695550606,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,87907,DB00722,10037153,319,25084,272,25760,0.025458931,1.204393928,1.020307518,1.422487066,0.074515672,DB0072210037153_,2.596745819,0.185976476,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,87908,DB00158,10037855,39,16776,17,8087,0.777175465,1.105889258,0.610681833,2.086169695,0.878512755,DB0015810037855_,0.129524852,0.100649769,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,87910,DB00722,10037855,41,25362,46,25986,0.747726004,0.913252563,0.584320153,1.422877697,0.85664377,DB0072210037855_,0.154733118,-0.090742806,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,87913,DB00563,10037884,112,46534,30,15318,0.380701997,1.228923447,0.814748553,1.906114537,0.550729333,DB0056310037884_,0.596511819,0.20613854,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,87919,DB00158,10040984,43,16772,19,8085,0.892107669,1.090957001,0.62182826,1.983587776,0.955096007,DB0015810040984_,0.045943412,0.087055294,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,folic acid,DB00158
,87921,DB00722,10040984,77,25326,77,25955,0.935710065,1.024840487,0.737074513,1.424940915,0.975900766,DB0072210040984_,0.024394372,0.024536978,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,87925,DB00722,10062519,53,25350,20,26012,8.45787928363121e-05,2.71924637,1.598009673,4.803733324,0.000691709,DB0072210062519_,7.276344832,1.000354772,female,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,87927,DB00060,10067482,40,9468,13,2452,0.4954115,0.796870468,0.416731056,1.626496438,0.657721103,DB0006010067482_,0.418974293,-0.227063138,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,87931,DB00588,10067482,74,16450,38,8430,1,0.997952278,0.665485946,1.518479598,1,DB0058810067482_,0,-0.002049822,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,87932,DB00641,10067482,56,14068,38,12437,0.215714071,1.302814867,0.847092775,2.023265353,0.368280355,DB0064110067482_,0.998910796,0.264527206,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,87934,DB00422,10022437,90,3345,76,2873,0.937260547,1.017110029,0.73792028,1.40500451,0.977265797,DB0042210022437_,0.02299661,0.016965301,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,methylphenidate,DB00422
,87937,DB00211,10003549,69,1367,97,1534,0.174300209,0.798300734,0.572442955,1.10835706,0.316533282,DB0021110003549_,1.150326887,-0.225269893,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,midodrine,DB00211
,87942,DB00211,10020919,37,1399,20,1611,0.006965303,2.129842876,1.198126172,3.891962888,0.026686755,DB0021110020919_,3.623587913,0.75604821,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,midodrine,DB00211
,87944,DB01240,10034474,87,5664,25,1551,0.817101933,0.952946502,0.602396293,1.557806867,0.902146946,DB0124010034474_,0.102977861,-0.048196513,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,epoprostenol,DB01240
,87945,DB08932,10034474,193,19250,52,6545,0.140657995,1.261901651,0.923399314,1.751238984,0.270767541,DB0893210034474_,1.306494609,0.23261983,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,macitentan,DB08932
,87947,DB08932,10047895,661,18782,174,6423,0.002107831,1.299085612,1.094895008,1.548015267,0.010156616,DB0893210047895_,4.589629931,0.261660642,NA,10047895,Weight decreased,10022891,Investigations,Inv,macitentan,DB08932
,87953,DB00737,10012174,57,2744,15,917,0.492295399,1.26980937,0.705168003,2.427174137,0.655189092,DB0073710012174_,0.422831396,0.238866787,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,meclizine,DB00737
,87962,DB00186,10005724,88,16813,31,9977,0.013117408,1.684486851,1.106216005,2.627118013,0.044206818,DB0018610005724_,3.118876241,0.521460978,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,lorazepam,DB00186
,87963,DB00335,10005724,43,8423,21,5444,0.307948156,1.323402235,0.767341221,2.350474417,0.475136023,DB0033510005724_,0.744154151,0.280205871,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,atenolol,DB00335
,87966,DB11089,10005724,74,10101,31,8376,0.001111676,1.97934012,1.283655405,3.118798855,0.006007482,DB1108910005724_,5.114749625,0.682763516,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,docusate,DB11089
,87970,DB11365,10013573,63,1582,37,1511,0.02486927,1.626034313,1.05957809,2.52668727,0.073209627,DB1136510013573_,2.614428353,0.486144114,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sennosides,DB11365
,87971,DB00653,10016256,76,1016,37,785,0.024360811,1.586667801,1.04489202,2.445800903,0.072088256,DB0065310016256_,2.629864139,0.461636094,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,magnesium sulfate,DB00653
,87973,DB00497,10028411,140,19127,99,16276,0.171509722,1.203347659,0.922839991,1.574114114,0.312823575,DB0049710028411_,1.162115907,0.185107389,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,87976,DB11089,10028411,87,10088,60,8347,0.318173542,1.199744766,0.8524386,1.698198716,0.486147273,DB1108910028411_,0.721243669,0.182108839,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,87978,DB00335,10030095,51,8415,34,5431,0.911481217,0.968075295,0.614260983,1.543107637,0.96027793,DB0033510030095_,0.040532526,-0.032445411,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,87981,DB00761,10030095,247,15060,102,8523,0.008205836,1.370436126,1.082024383,1.746218726,0.030411449,DB0076110030095_,3.492936138,0.315129029,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,87986,DB00169,10010214,37,38654,20,18155,0.670045953,0.868918307,0.49125285,1.580425847,0.799758272,DB0016910010214_,0.223445757,-0.140506166,NA,10010214,Compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,87994,DB00230,10029412,54,19620,33,8618,0.161115651,0.718764704,0.457353356,1.145214225,0.298992155,DB0023010029412_,1.207337944,-0.330221229,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,87995,DB00316,10029412,84,65390,52,36901,0.593151748,0.911599354,0.637358693,1.314563756,0.73928181,DB0031610029412_,0.302076092,-0.09255469,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,87998,DB00316,10040742,87,65387,30,36923,0.020426929,1.637575842,1.070007006,2.570163222,0.062841618,DB0031610040742_,2.767137721,0.493217003,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,88001,DB01164,10017955,29,6495,60,7876,0.018494491,0.586124337,0.362242883,0.928956497,0.058085911,DB0116410017955_,2.845832148,-0.534223334,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,calcium chloride,DB01164
,88002,DB00190,10001497,43,3254,129,4545,6.95843471073348e-06,0.465625589,0.320782211,0.664393108,7.90246084992998e-05,DB0019010001497_,9.445751254,-0.764373426,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,88003,DB00193,10001497,54,19266,40,8662,0.018805208,0.6069713,0.395512682,0.938469221,0.058865653,DB0019310001497_,2.832497492,-0.499273771,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,88004,DB00915,10001497,21,1434,33,1018,0.004957963,0.451897291,0.246943918,0.810041634,0.0203309,DB0091510001497_,3.895613399,-0.794300356,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,amantadine,DB00915
,88006,DB00190,10003239,39,3258,26,4648,0.00330387,2.139779839,1.26713087,3.668771187,0.014626061,DB0019010003239_,4.224950358,0.760702945,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,carbidopa,DB00190
,88011,DB00190,10003988,17,3280,34,4640,0.257530479,0.707347284,0.369927346,1.304383351,0.418431249,DB0019010003988_,0.871242683,-0.346233526,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,carbidopa,DB00190
,88035,DB00915,10013916,40,1415,37,1014,0.291847139,0.774799222,0.479207429,1.255631926,0.457286045,DB0091510013916_,0.782446166,-0.255151351,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,amantadine,DB00915
,88038,DB00915,10016173,156,1299,135,916,0.114094458,0.814922495,0.632902933,1.050224398,0.232289441,DB0091510016173_,1.459771093,-0.204662268,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,amantadine,DB00915
,88042,DB00915,10017577,75,1380,50,1001,0.710192483,1.088030794,0.743250289,1.604182726,0.827144445,DB0091510017577_,0.189775938,0.084369452,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,amantadine,DB00915
,88045,DB00915,10019063,97,1358,129,922,1.88808976446884e-06,0.510652005,0.383034095,0.679069038,2.51665514498293e-05,DB0091510019063_,10.58999477,-0.672066928,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,amantadine,DB00915
,88046,DB00190,10020642,34,3263,39,4635,0.403682802,1.238317133,0.75652129,2.018059608,0.573355441,DB0019010020642_,0.556249439,0.213753307,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,carbidopa,DB00190
,88071,DB00363,10029379,203,4425,293,6595,0.743249,1.032611098,0.855495638,1.244443836,0.853113535,DB0036310029379_,0.158862639,0.032090641,NA,10029379,Neutrophilia,10005329,Blood and lymphatic system disorders,Blood,clozapine,DB00363
,88085,DB00363,10043071,45,4583,91,6797,0.094866418,0.733415506,0.500308201,1.061751588,0.203012548,DB0036310043071_,1.594487491,-0.310042881,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,clozapine,DB00363
,88112,DB00564,10012378,57,2547,29,1434,0.733745978,1.106603299,0.692220291,1.803804213,0.84562153,DB0056410012378_,0.167683384,0.101295232,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,carbamazepine,DB00564
,88114,DB00455,10042464,36,9365,16,5102,0.562525001,1.225731135,0.662343139,2.368261628,0.714753401,DB0045510042464_,0.335817689,0.203537511,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,loratadine,DB00455
,88160,DB01268,10040844,52,2091,75,3055,1,1.012976804,0.693963724,1.46906266,1,DB0126810040844_,0,0.012893327,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,sunitinib,DB01268
,88162,DB00230,10038695,62,19612,41,8610,0.052990816,0.663889623,0.439988684,1.01127827,0.130615403,DB0023010038695_,2.035498126,-0.409639374,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,88164,DB08932,10013709,130,19313,67,6530,0.006503291,0.656054448,0.484199689,0.895900867,0.025255079,DB0893210013709_,3.678728001,-0.421511493,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,88168,DB00181,10007617,49,9807,35,5836,0.429388714,0.833136804,0.528315592,1.326301455,0.597877421,DB0018110007617_,0.514369528,-0.18255742,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,baclofen,DB00181
,88169,DB00327,10007617,62,6076,33,4229,0.248993291,1.307634991,0.842187715,2.063707233,0.408423892,DB0032710007617_,0.895449692,0.268220155,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,hydromorphone,DB00327
,88170,DB00575,10007617,51,5193,30,3799,0.367759519,1.243624996,0.775468822,2.02657364,0.537462071,DB0057510007617_,0.620897087,0.218030498,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,clonidine,DB00575
,88171,DB00181,10021143,39,9817,29,5842,0.380404514,0.800316718,0.481729602,1.343493147,0.550435311,DB0018110021143_,0.597045838,-0.222747732,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,baclofen,DB00181
,88172,DB00327,10021143,61,6077,66,4196,0.013951583,0.638208105,0.442030086,0.920136948,0.046440494,DB0032710021143_,3.069583491,-0.449090865,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydromorphone,DB00327
,88173,DB00575,10021143,30,5214,32,3797,0.155494412,0.682758551,0.400030595,1.162427256,0.291475157,DB0057510021143_,1.2328005,-0.381613995,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonidine,DB00575
,88174,DB00181,10028596,42,9814,38,5833,0.064008967,0.656962776,0.412888968,1.048283989,0.150664969,DB0018110028596_,1.892696659,-0.420127919,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,baclofen,DB00181
,88181,DB08932,10068319,361,19082,64,6533,2.71114298473805e-07,1.931189275,1.474421412,2.564225381,4.45807903370909e-06,DB0893210068319_,12.32079259,0.658136018,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,88184,DB00996,10061422,59,38894,55,22370,0.011158467,0.617017065,0.419814806,0.908005237,0.038850294,DB0099610061422_,3.248039627,-0.482858597,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,88185,DB00338,10005750,315,33359,184,22088,0.183068567,1.133567822,0.941281605,1.368267628,0.327734193,DB0033810005750_,1.115552385,0.125370023,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,omeprazole,DB00338
,88187,DB01136,10005750,139,9745,100,11015,0.000671575,1.571099906,1.204475574,2.055609956,0.003958814,DB0113610005750_,5.531810866,0.451775951,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,carvedilol,DB01136
,88189,DB00316,10029350,21,65453,31,36922,0.000719661,0.382134099,0.208666039,0.686755382,0.004190118,DB0031610029350_,5.47502633,-0.961983687,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,88193,DB00188,10028596,24,7862,57,8771,0.001638311,0.469770113,0.278528025,0.770042925,0.008255153,DB0018810028596_,4.796917632,-0.755511826,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,bortezomib,DB00188
,88194,DB00787,10028596,64,16936,91,17157,0.043814414,0.712484005,0.508853612,0.99250395,0.11320213,DB0078710028596_,2.178580295,-0.338997817,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,acyclovir,DB00787
,88196,DB00186,10061623,93,16808,72,9936,0.089974147,0.763589091,0.554743984,1.054676744,0.195145676,DB0018610061623_,1.634008941,-0.269725473,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,88197,DB00188,10061623,100,7786,103,8725,0.571862101,1.087950064,0.816435621,1.4493446,0.721969035,DB0018810061623_,0.325773028,0.08429525,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,88198,DB00193,10061623,106,19214,63,8639,0.080510465,0.756488572,0.548128405,1.051552805,0.179277609,DB0019310061623_,1.718819789,-0.279067852,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,88199,DB00264,10061623,202,29405,175,24717,0.795405068,0.970250213,0.787969083,1.19570331,0.889265654,DB0026410061623_,0.117359265,-0.030201289,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,88200,DB00381,10061623,194,29166,148,22739,0.869791619,1.021962874,0.820298528,1.275331689,0.942090076,DB0038110061623_,0.059654387,0.021725164,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,88201,DB00787,10061623,245,16755,282,16966,0.147606172,0.879739092,0.737287164,1.049167648,0.280669023,DB0078710061623_,1.270579159,-0.128129902,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,88202,DB00904,10061623,169,22900,116,14340,0.463655816,0.912313447,0.715349225,1.166861084,0.630888734,DB0090410061623_,0.460625765,-0.091771656,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,88204,DB01104,10061623,79,15384,40,7246,0.694756872,0.930247033,0.627495348,1.398465546,0.816266888,DB0110410061623_,0.203013909,-0.072305102,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,88205,DB01234,10061623,353,31272,380,32508,0.655760622,0.965655968,0.832323893,1.120129843,0.789387371,DB0123410061623_,0.236498114,-0.034947649,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,88210,DB00471,10041349,165,14024,46,5419,0.053293495,1.38596749,0.992566954,1.969122031,0.131169018,DB0047110041349_,2.031268573,0.326398445,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,88214,DB08932,10013952,116,19327,18,6579,0.000955285,2.193784881,1.32721914,3.83457732,0.00530467,DB0893210013952_,5.239167744,0.785628308,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,88216,DB00398,10005191,48,679,81,1457,0.207421097,1.271405999,0.860208153,1.86246868,0.358122933,DB0039810005191_,1.026878962,0.240123374,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,sorafenib,DB00398
,88217,DB00398,10015150,28,699,44,1494,0.247784851,1.35997375,0.808023677,2.254972273,0.407094077,DB0039810015150_,0.898710974,0.307465398,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,sorafenib,DB00398
,88218,DB00421,10015150,81,8822,24,5228,0.002220997,1.999966,1.253088046,3.303202813,0.010596047,DB0042110015150_,4.547274314,0.69313018,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,spironolactone,DB00421
,88225,DB00421,10061428,183,8720,107,5145,1,1.009104158,0.788580055,1.296545516,1,DB0042110061428_,0,0.009062965,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,spironolactone,DB00421
,88229,DB00213,10005725,33,18862,34,13387,0.136911348,0.688880391,0.413281856,1.146927753,0.265382161,DB0021310005725_,1.326584376,-0.372687621,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,pantoprazole,DB00213
,88246,DB00316,10038743,87,65387,49,36904,1,1.002086465,0.698021203,1.453074415,1,DB0031610038743_,0,0.002084291,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,88248,DB00381,10038743,34,29326,23,22864,0.689097574,1.15250447,0.659180225,2.049838166,0.81249806,DB0038110038743_,0.207641753,0.141937374,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,88252,DB00904,10038743,37,23032,21,14435,0.787899664,1.104264918,0.629407953,1.986352005,0.885095921,DB0090410038743_,0.122059255,0.099179881,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,88253,DB01075,10038743,38,19910,22,11075,0.893205612,0.960824515,0.553614594,1.706355425,0.955474763,DB0107510038743_,0.045546928,-0.039963493,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,88260,DB00016,10040047,36,2726,38,2252,0.346764078,0.782681522,0.480343301,1.273165577,0.516179284,DB0001610040047_,0.661301125,-0.245029406,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,erythropoietin,DB00016
,88261,DB00153,10040047,74,7349,54,3385,0.012661221,0.631225752,0.437377334,0.916073309,0.042964134,DB0015310040047_,3.147389601,-0.460091712,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ergocalciferol,DB00153
,88262,DB00196,10040047,100,4983,97,3188,0.00489617,0.659616306,0.491977949,0.884604362,0.020127592,DB0019610040047_,3.905663659,-0.416096967,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,fluconazole,DB00196
,88290,DB00588,10016334,52,16472,11,8457,0.004899391,2.426987157,1.250214947,5.161849016,0.020137061,DB0058810016334_,3.90519333,0.886650635,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,88291,DB00682,10016334,76,19383,20,16344,5.11464051065985e-07,3.203993926,1.936195942,5.540190356,7.91512074316715e-06,DB0068210016334_,11.74673561,1.164398134,female,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,88292,DB00996,10016334,97,38856,42,22383,0.133880287,1.330395228,0.916886095,1.960023776,0.261153494,DB0099610016334_,1.342646943,0.285476062,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,88294,DB00181,10002855,196,9660,96,5775,0.126680919,1.2205093,0.949135057,1.57836309,0.251022085,DB0018110002855_,1.382214357,0.199268231,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,88297,DB00181,10046306,54,9802,29,5842,0.73315892,1.109803878,0.693329633,1.809844947,0.845167301,DB0018110046306_,0.168220681,0.104183313,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,baclofen,DB00181
,88299,DB00273,10046306,63,8418,12,2181,0.390387131,1.360167145,0.72512205,2.776340223,0.560238357,DB0027310046306_,0.579392948,0.307607593,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,topiramate,DB00273
,88300,DB00471,10046306,228,13961,58,5407,0.004157341,1.522488791,1.134551941,2.071475764,0.017625113,DB0047110046306_,4.038430499,0.420346358,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,montelukast,DB00471
,88302,DB00115,10060800,132,18293,28,10444,2.27037541082797e-07,2.691432761,1.77801906,4.207548604,3.8047062590764e-06,DB0011510060800_,12.47927177,0.990073677,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,cyanocobalamin,DB00115
,88305,DB00471,10060800,66,14123,14,5451,0.044628106,1.819537499,1.010607239,3.511276288,0.114836002,DB0047110060800_,2.164250238,0.598582347,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,montelukast,DB00471
,88306,DB05676,10060800,100,47029,14,25315,5.77529210325514e-08,3.844820992,2.187216996,7.287685964,1.09962733019965e-06,DB0567610060800_,13.72053923,1.346727046,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,apremilast,DB05676
,88309,DB01216,10001760,6,230,65,7050,0.025919912,2.828757132,0.991236145,6.590815008,0.075511763,DB0121610001760_,2.583466838,1.039837439,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,finasteride,DB01216
,88311,DB06228,10018830,60,15852,95,15981,0.006112984,0.636731023,0.45265987,0.889614312,0.024026884,DB0622810018830_,3.728581918,-0.451407968,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,88313,DB08889,10035664,139,3026,207,3678,0.07606418,0.816206463,0.649951214,1.022576658,0.171587802,DB0888910035664_,1.76266018,-0.203087937,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,carfilzomib,DB08889
,88314,DB01129,10013709,40,872,30,406,0.0655052,0.621019716,0.37122094,1.048587309,0.153321834,DB0112910013709_,1.87521608,-0.476392449,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,rabeprazole,DB01129
,88320,DB00334,10019063,54,2795,50,2762,0.767207622,1.067266362,0.710115768,1.606624083,0.872045507,DB0033410019063_,0.136913669,0.065100577,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,88321,DB01238,10019063,41,5209,53,3449,0.001406969,0.512238797,0.331399192,0.786760547,0.007288567,DB0123810019063_,4.921448259,-0.668964363,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,88328,DB06228,10025482,337,15575,155,15921,2.75624675205842e-17,2.222449938,1.829601158,2.709321167,2.2087788377395e-15,DB0622810025482_,33.74633659,0.798610163,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,88329,DB08932,10069868,89,19354,17,6580,0.025350629,1.779774852,1.050619032,3.193272784,0.074268979,DB0893210069868_,2.600061923,0.576486868,NA,10069868,Device issue,10077536,Product issues,Prod,macitentan,DB08932
,88330,DB00051,10002556,36,25695,37,11383,0.00049782,0.431037384,0.264571992,0.701635729,0.003080322,DB0005110002556_,5.782721263,-0.841560456,NA,10002556,Ankylosing spondylitis,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,88335,DB06674,10025482,77,4429,24,1466,0.907595371,1.061939366,0.661188714,1.763347471,0.958771936,DB0667410025482_,0.042102046,0.060096827,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,golimumab,DB06674
,88336,DB06674,10028810,44,4462,15,1475,0.880553076,0.969673193,0.527508907,1.881590524,0.950039512,DB0667410028810_,0.051251704,-0.030796179,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,golimumab,DB06674
,88346,DB00331,10040560,123,24823,157,20595,0.000368223,0.650013556,0.508729941,0.828948482,0.002393954,DB0033110040560_,6.034809054,-0.430762061,NA,10040560,Shock,10047065,Vascular disorders,Vasc,metformin,DB00331
,88347,DB00331,10043089,35,24911,17,20735,0.070623849,1.713665093,0.934331572,3.262952791,0.16239593,DB0033110043089_,1.817717916,0.538634406,NA,10043089,Tachypnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,88348,DB00331,10058151,35,24911,20,20732,0.222359097,1.456410135,0.817533465,2.663293077,0.376458656,DB0033110058151_,0.976947049,0.375974596,NA,10058151,Pulseless electrical activity,10007541,Cardiac disorders,Card,metformin,DB00331
,88349,DB08932,10005734,262,19181,74,6523,0.165360655,1.204039014,0.925351297,1.582895596,0.304611733,DB0893210005734_,1.188717319,0.18568175,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,macitentan,DB08932
,88350,DB08932,10019304,74,19369,26,6571,0.908297891,0.965566816,0.609592966,1.574658729,0.958996855,DB0893210019304_,0.041867483,-0.035039976,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,macitentan,DB08932
,88354,DB00321,10016322,148,7299,48,2802,0.334262842,1.183628965,0.846696025,1.680290699,0.503371554,DB0032110016322_,0.686426705,0.168585113,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,88357,DB00404,10027374,42,19850,8,9854,0.009892422,2.606148979,1.208126192,6.429281078,0.035252483,DB0040410027374_,3.345219305,0.957873645,NA,10027374,Mental impairment,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,88358,DB00497,10027374,34,19233,31,16344,0.80411595,0.932045008,0.555564883,1.568783502,0.894066865,DB0049710027374_,0.111974713,-0.070374174,NA,10027374,Mental impairment,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,88360,DB00996,10027374,61,38892,34,22391,0.915489821,1.032914995,0.668042616,1.621302523,0.962143444,DB0099610027374_,0.03859173,0.032384897,NA,10027374,Mental impairment,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,88364,DB00338,10064366,35,33639,17,22255,0.323701973,1.36207526,0.742669409,2.593347294,0.492148328,DB0033810064366_,0.708975128,0.309009463,NA,10064366,Extra dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,88372,DB01156,10043882,46,13576,26,6302,0.447013113,0.821306679,0.496616204,1.385380062,0.614783366,DB0115610043882_,0.486485324,-0.196858696,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,bupropion,DB01156
,88373,DB01156,10047340,71,13551,18,6310,0.02182532,1.836674268,1.081926407,3.277594864,0.066221694,DB0115610047340_,2.71474717,0.607956473,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,bupropion,DB01156
,88374,DB01156,10047513,133,13489,28,6300,5.53806303134777e-05,2.218399105,1.46536695,3.468393096,0.000481854,DB0115610047513_,7.637870127,0.796785812,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,bupropion,DB01156
,88382,DB01076,10001949,109,25638,99,25484,0.532308417,1.094376344,0.825491783,1.452370885,0.689128807,DB0107610001949_,0.372327078,0.090184652,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,88383,DB01076,10069326,51,25696,60,25523,0.393435877,0.844281114,0.569379569,1.247756293,0.563358298,DB0107610069326_,0.573839445,-0.169269767,NA,10069326,Product substitution issue,10077536,Product issues,Prod,atorvastatin,DB01076
,88391,DB01076,10009802,39,25708,24,25559,0.076839832,1.615557498,0.947138223,2.809280541,0.172915113,DB0107610009802_,1.75495448,0.479680097,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,atorvastatin,DB01076
,88401,DB00476,10013971,62,17195,19,6158,0.614728474,1.168614534,0.688905851,2.071251941,0.756183917,DB0047610013971_,0.279470655,0.155818888,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,88405,DB00581,10037087,43,2070,19,2050,0.003038767,2.240889494,1.273138185,4.086676689,0.013661846,DB0058110037087_,4.293148262,0.806872883,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,lactulose,DB00581
,88407,DB08932,10028411,553,18890,155,6442,0.035379562,1.216679314,1.013963902,1.466816922,0.096233435,DB0893210028411_,2.340978425,0.196125274,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,88408,DB08932,10052840,39,19404,15,6582,0.641520005,0.881960615,0.474978563,1.723384224,0.778196614,DB0893210052840_,0.250776069,-0.125607878,NA,10052840,Cardiac flutter,10007541,Cardiac disorders,Card,macitentan,DB08932
,88421,DB00620,10003553,52,4776,11,3121,0.000237285,3.088771115,1.589069407,6.574680368,0.001661439,DB0062010003553_,6.400071351,1.127773314,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,triamcinolone,DB00620
,88423,DB00695,10003553,174,27875,36,20492,9.55773488059772e-15,3.553049103,2.468819253,5.24144021,5.64550699632609e-13,DB0069510003553_,28.2027462,1.267806137,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,88424,DB00904,10003553,102,22967,26,14430,1.50226185367796e-05,2.464779946,1.588648185,3.953084249,0.000155247,DB0090410003553_,8.770496241,0.902102532,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,88425,DB01234,10003553,92,31533,31,32857,6.48469921564588e-09,3.092414131,2.037687273,4.810069606,1.51984234403256e-07,DB0123410003553_,15.69948904,1.128952058,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,88428,DB08932,10000059,506,18937,151,6446,0.17284017,1.140642535,0.94704866,1.380318531,0.314597596,DB0893210000059_,1.156460931,0.131591731,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,88437,DB00650,10028116,37,2094,37,1977,0.81560708,0.944114221,0.579567993,1.538003768,0.901144687,DB0065010028116_,0.104089449,-0.057508123,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,leucovorin,DB00650
,88440,DB00987,10042128,17,2087,61,2867,0.000280013,0.382915408,0.209017384,0.666487131,0.001908997,DB0098710042128_,6.261177066,-0.959941182,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,cytarabine,DB00987
,88441,DB00741,10047895,92,4002,66,3108,0.685287891,1.082561201,0.777650629,1.51394379,0.809927707,DB0074110047895_,0.210810286,0.079329716,NA,10047895,Weight decreased,10022891,Investigations,Inv,hydrocortisone,DB00741
,88447,DB00331,10003598,24,24922,34,20718,0.047807982,0.586824381,0.332804713,1.019446895,0.120987129,DB0033110003598_,2.112071112,-0.533029685,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,88452,DB00331,10018884,194,24752,179,20573,0.321520071,0.900818622,0.730765759,1.110928174,0.489808453,DB0033110018884_,0.713740876,-0.104451349,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,metformin,DB00331
,88462,DB00635,10050819,56,32997,28,23766,0.121897647,1.44048423,0.899361443,2.35602062,0.244111054,DB0063510050819_,1.410132018,0.364979328,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,88481,DB00169,10029412,50,38641,34,18141,0.101347801,0.690396999,0.437593677,1.101254212,0.21288424,DB0016910029412_,1.547006734,-0.370488486,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,88482,DB00404,10040984,103,19789,30,9832,0.009492551,1.705795096,1.125462508,2.656487542,0.034149277,DB0040410040984_,3.377013853,0.534031334,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,88483,DB00999,10040984,73,21357,42,12197,1,0.99262642,0.669550578,1.488497477,1,DB0099910040984_,0,-0.007400899,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,88484,DB00169,10042682,191,38500,37,18138,1.00588752441045e-07,2.431949446,1.702311826,3.560246244,1.81966645417265e-06,DB0016910042682_,13.21685734,0.888693177,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,88495,DB00005,10046851,83,127999,49,42370,0.001715547,0.560712287,0.389189292,0.815457256,0.008572029,DB0000510046851_,4.759250781,-0.578547363,NA,10046851,Uveitis,10015919,Eye disorders,Eye,etanercept,DB00005
,88513,DB00252,10016256,68,2164,52,1856,0.577665261,1.121523099,0.765751521,1.650792278,0.726599784,DB0025210016256_,0.319379456,0.114687672,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,phenytoin,DB00252
,88515,DB00252,10041349,25,2207,43,1865,0.004639226,0.491390577,0.286457402,0.826467536,0.019251903,DB0025210041349_,3.950145363,-0.710515995,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,phenytoin,DB00252
,88521,DB00480,10060933,149,67279,185,67477,0.055136069,0.807778498,0.646423072,1.008019724,0.13457612,DB0048010060933_,2.005625294,-0.213467394,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,88525,DB00281,10006093,81,11377,77,5594,5.63685246978853e-05,0.517238867,0.373291986,0.71727695,0.000489113,DB0028110006093_,7.622917295,-0.659250486,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,lidocaine,DB00281
,88526,DB00575,10006093,102,5142,94,3735,0.107667484,0.788217567,0.587731761,1.05798803,0.222679976,DB0057510006093_,1.502019623,-0.237981127,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,clonidine,DB00575
,88536,DB06605,10015150,60,14013,38,12995,0.068584679,1.46421639,0.958617887,2.261466905,0.158748527,DB0660510015150_,1.840433917,0.381320212,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,apixaban,DB06605
,88537,DB06605,10048959,329,13744,216,12817,6.58852446268214e-05,1.420392238,1.190612089,1.697227876,0.000557205,DB0660510048959_,7.492577045,0.350933057,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,88538,DB08910,10028596,59,16685,121,17367,1.27568654300793e-05,0.507546254,0.365014764,0.698968406,0.000134475,DB0891010028596_,8.914129878,-0.678167431,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,pomalidomide,DB08910
,88539,DB00169,10016970,113,38578,17,18158,1.05004856833436e-06,3.128567276,1.869126864,5.560792792,1.49393919451521e-05,DB0016910016970_,11.11150908,1.14057516,female,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,88540,DB00476,10016970,50,17207,9,6168,0.05454254,1.991465866,0.968807372,4.60897592,0.133530541,DB0047610016970_,2.013425052,0.688870984,NA,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,88541,DB00480,10016970,84,67344,26,67636,1.59484385112777e-08,3.245033971,2.068220373,5.250939474,3.41371910642455e-07,DB0048010016970_,14.89029331,1.177125819,female,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,88551,DB00480,10037867,132,67296,89,67573,0.003726392,1.489238714,1.129378737,1.971455374,0.016100635,DB0048010037867_,4.128896588,0.398265059,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,88554,DB00695,10037867,54,27995,34,20494,0.518578597,1.162654872,0.74301171,1.842560886,0.677830797,DB0069510037867_,0.388857584,0.150706073,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,88561,DB01373,10037867,48,22672,15,7366,1,1.039682238,0.57193314,2.000078903,1,DB0137310037867_,0,0.038915126,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,88576,DB01373,10041541,48,22672,13,7368,0.655831387,1.199923621,0.639478872,2.415561639,0.789436402,DB0137310041541_,0.236436003,0.182257905,NA,10041541,Spinal compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,88617,DB01076,10029331,259,25488,275,25308,0.459657072,0.935139475,0.785395329,1.113236916,0.627119596,DB0107610029331_,0.466618013,-0.067059589,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,88618,DB00275,10061428,32,2028,20,1217,0.886062562,0.960196141,0.529851069,1.779893358,0.952601516,DB0027510061428_,0.0485586,-0.040617701,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,olmesartan,DB00275
,88629,DB05259,10028596,39,11231,16,2712,0.086262286,0.588621056,0.320854263,1.13005244,0.188793022,DB0525910028596_,1.667103988,-0.529972671,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,glatiramer,DB05259
,88636,DB00043,10024570,52,6361,19,2281,1,0.981409645,0.569080993,1.761723705,1,DB0004310024570_,0,-0.018765328,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,omalizumab,DB00043
,88637,DB00051,10007882,105,25626,83,11337,0.000127841,0.559700297,0.415300111,0.756326049,0.000983958,DB0005110007882_,6.923927299,-0.580353823,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,adalimumab,DB00051
,88638,DB00327,10013700,693,5445,144,4118,3.80671605904767e-53,3.639098218,3.022491785,4.406008605,2.47060571881649e-50,DB0032710013700_,114.2247913,1.291735909,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,hydromorphone,DB00327
,88642,DB00186,10018836,34,16867,23,9985,0.681016081,0.875115607,0.500371545,1.556800274,0.807122451,DB0018610018836_,0.214279887,-0.13339928,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,88643,DB00381,10018836,77,29283,50,22837,0.325974443,1.200998603,0.830119697,1.751305896,0.494473582,DB0038110018836_,0.704261554,0.18315338,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,88645,DB00761,10018836,50,15257,35,8590,0.365248368,0.804335214,0.511406585,1.27760689,0.534854672,DB0076110018836_,0.625760211,-0.217739164,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,88649,DB00761,10018867,31,15276,46,8579,2.44077348077596e-05,0.378484399,0.231835706,0.610382762,0.0002367,DB0076110018867_,8.348715934,-0.971580424,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,potassium chloride,DB00761
,88652,DB00381,10042209,96,29264,33,22854,2.44055209598634e-05,2.271813721,1.514713254,3.48551925,0.0002367,DB0038110042209_,8.348715934,0.820578508,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,88653,DB00641,10042209,63,14061,22,12453,0.000111801,2.535957217,1.538085175,4.331298186,0.000878135,DB0064110042209_,7.037709718,0.930571166,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,88655,DB00761,10042209,49,15258,11,8614,0.004274389,2.514755888,1.289219767,5.366462261,0.018026251,DB0076110042209_,4.015926169,0.922175737,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,potassium chloride,DB00761
,88660,DB06605,10046571,265,13808,111,12922,1.90255840624597e-13,2.234016063,1.78106226,2.818101954,9.41784325954336e-12,DB0660510046571_,25.38841501,0.803800891,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,apixaban,DB06605
,88662,DB00950,10050584,45,4673,13,2043,0.200142076,1.513288841,0.80013841,3.064602655,0.349167654,DB0095010050584_,1.052203088,0.414285323,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,fexofenadine,DB00950
,88663,DB06605,10050584,208,13865,122,12911,4.9016071430056e-05,1.587575291,1.261837771,2.004420618,0.000434428,DB0660510050584_,7.741479708,0.462207878,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,88667,DB00091,10003549,124,5386,42,2628,0.044563973,1.440500018,1.004209861,2.102665473,0.114704663,DB0009110003549_,2.165394602,0.364990288,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,88672,DB00635,10031264,80,32973,44,23750,0.171530352,1.309604525,0.895162323,1.938176084,0.312830897,DB0063510031264_,1.162092499,0.269725203,NA,10031264,Osteonecrosis,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,88676,DB00959,10030124,77,8001,42,4960,0.569890578,1.136541016,0.769124798,1.699996756,0.720708886,DB0095910030124_,0.327519987,0.127989454,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,88678,DB06605,10037087,232,13841,137,12896,2.04912604188066e-05,1.577777954,1.27015189,1.96619304,0.000203997,DB0660510037087_,8.49740468,0.456017499,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,apixaban,DB06605
,88688,DB00007,10008479,18,1929,40,4412,0.887014552,1.029234186,0.553920934,1.842605481,0.953020806,DB0000710008479_,0.048118544,0.028815017,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,leuprolide,DB00007
,88691,DB14512,10008479,62,4782,20,2392,0.098676372,1.550561744,0.921246734,2.717118682,0.208866841,DB1451210008479_,1.566058355,0.438617281,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,88692,DB00007,10013968,34,1913,125,4327,0.011296913,0.61527695,0.406583147,0.909077532,0.039212856,DB0000710013968_,3.238750627,-0.485682787,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,leuprolide,DB00007
,88694,DB00275,10028813,138,1922,43,1194,7.07829030141174e-05,1.993322086,1.394397665,2.898954909,0.000592242,DB0027510028813_,7.431595028,0.689802637,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,olmesartan,DB00275
,88696,DB00275,10047700,54,2006,31,1206,0.909829469,1.047234861,0.657060565,1.695538109,0.959437782,DB0027510047700_,0.04140781,0.046153225,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,olmesartan,DB00275
,88714,DB00437,10028810,83,6838,103,11443,0.047624348,1.348446515,0.995951004,1.821160594,0.12062112,DB0043710028810_,2.115100883,0.2989532,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,allopurinol,DB00437
,88715,DB01076,10028810,358,25389,216,25367,3.5988320842565e-09,1.655944756,1.393462545,1.971592713,8.91147445451551e-08,DB0107610028810_,16.23334103,0.504371695,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,88717,DB00087,10043071,32,1337,18,729,1,0.969323872,0.523715638,1.847791395,1,DB0008710043071_,0,-0.03115649,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,alemtuzumab,DB00087
,88719,DB00059,10002198,25,802,34,1073,1,0.983761183,0.557855524,1.713560804,1,DB0005910002198_,0,-0.016372112,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,pegaspargase,DB00059
,88720,DB00563,10002198,114,46532,37,15311,1,1.013808905,0.693786829,1.512262644,1,DB0056310002198_,0,0.013714431,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,methotrexate,DB00563
,88728,DB00059,10021097,92,735,63,1044,1.98745138954055e-05,2.073475456,1.466808326,2.946015834,0.000198745,DB0005910021097_,8.523487263,0.729226164,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,pegaspargase,DB00059
,88729,DB01033,10021097,41,1141,26,1278,0.025544758,1.765844716,1.047084719,3.027660275,0.074708646,DB0103310021097_,2.594159456,0.568629169,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,mercaptopurine,DB01033
,88731,DB00531,10037087,50,7202,37,6479,0.390307348,1.215672475,0.777811812,1.91543625,0.560141482,DB0053110037087_,0.579565881,0.195297401,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,cyclophosphamide,DB00531
,88738,DB00563,10045555,27,46619,49,15299,3.00127838688918e-13,0.180834407,0.108639997,0.295155487,1.44882649034678e-11,DB0056310045555_,24.95768211,-1.710173545,male,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,88749,DB01018,10053762,26,386,49,730,1,1.003486894,0.588800347,1.676261702,1,DB0101810053762_,0,0.003480829,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,guanfacine,DB01018
,88751,DB08895,10033557,138,27976,12,6634,0.000232602,2.726988357,1.510742052,5.408742494,0.001634309,DB0889510033557_,6.416535448,1.003197834,female,10033557,Palpitations,10007541,Cardiac disorders,Card,tofacitinib,DB08895
,88752,DB01611,10040753,297,11616,27,2334,1.99913505243306e-05,2.21010772,1.484048266,3.41882364,0.000199648,DB0161110040753_,8.518956431,0.793041257,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,hydroxychloroquine,DB01611
,88755,DB00887,10002034,100,2241,67,1748,0.381205808,1.164147979,0.840132616,1.621625651,0.551230623,DB0088710002034_,0.595602004,0.151989471,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,bumetanide,DB00887
,88756,DB00678,10011906,474,15125,506,10218,2.86337730319036e-12,0.632875597,0.555727341,0.72059668,1.19656394935387e-10,DB0067810011906_,22.84639686,-0.457481406,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,88757,DB00887,10011906,179,2162,157,1658,0.251357817,0.874374041,0.694880296,1.101064075,0.411314214,DB0088710011906_,0.888397846,-0.13424703,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,88758,DB11133,10011906,45,2386,48,1526,0.017684614,0.5996917,0.388153283,0.925024694,0.056103457,DB1113310011906_,2.880557852,-0.51133959,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,88763,DB01024,10012735,129,2082,78,2042,0.001007911,1.621883226,1.206488865,2.191838866,0.00554014,DB0102410012735_,5.195735439,0.483587959,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,mycophenolic acid,DB01024
,88764,DB00864,10047895,68,6801,97,8295,0.345612582,0.85503796,0.616612708,1.179939326,0.515033972,DB0086410047895_,0.663522415,-0.156609413,NA,10047895,Weight decreased,10022891,Investigations,Inv,tacrolimus,DB00864
,88767,DB01109,10010264,69,4343,57,4213,0.419337706,1.174268575,0.812564473,1.70272969,0.588376655,DB0110910010264_,0.530387967,0.160645464,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,88768,DB01109,10016825,37,4375,18,4252,0.014856898,1.997602237,1.106841913,3.733338231,0.048936538,DB0110910016825_,3.017230967,0.69194758,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,heparin,DB01109
,88770,DB00480,10029354,897,66531,890,66772,0.811824099,1.011516983,0.920293676,1.111731268,0.898935166,DB0048010029354_,0.106544366,0.011451168,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,lenalidomide,DB00480
,88774,DB08931,10010774,306,6271,106,2340,0.533251126,1.07718614,0.856289955,1.363547092,0.69002638,DB0893110010774_,0.37102545,0.074352215,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,88775,DB00559,10013971,269,9390,60,3246,0.002044199,1.5497136,1.163975914,2.09212768,0.009897368,DB0055910013971_,4.615486462,0.43807014,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,88776,DB08931,10013971,533,6044,172,2274,0.09370697,1.165880742,0.973056556,1.40220118,0.201273766,DB0893110013971_,1.603089278,0.153476803,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,88777,DB08931,10016825,219,6358,51,2395,0.001716025,1.617512304,1.18304002,2.247488991,0.00857269,DB0893110016825_,4.75917367,0.480889354,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,riociguat,DB08931
,88778,DB00374,10028836,121,17595,24,5700,0.025697054,1.633191024,1.046376522,2.649991842,0.075024664,DB0037410028836_,2.589938364,0.490535785,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,88782,DB00005,10006272,60,128022,7,42412,0.004428316,2.839708692,1.296628769,7.365089678,0.018533283,DB0000510006272_,3.988187078,1.043701474,female,10006272,Breast mass,10038604,Reproductive system and breast disorders,Repro,etanercept,DB00005
,88783,DB00005,10006298,60,128022,7,42412,0.004428316,2.839708692,1.296628769,7.365089678,0.018533283,DB0000510006298_,3.988187078,1.043701474,female,10006298,Breast pain,10038604,Reproductive system and breast disorders,Repro,etanercept,DB00005
,88784,DB00005,10061284,68,128014,26,42393,0.550790365,0.866130141,0.543778637,1.418493977,0.704828253,DB0000510061284_,0.349801118,-0.143720104,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,88787,DB13961,10003285,64,9393,21,6393,0.002688326,2.074153316,1.248543416,3.579575265,0.012365499,DB1396110003285_,4.392844986,0.72955303,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,88790,DB13961,10016322,197,9260,103,6311,0.032388234,1.303493616,1.019620137,1.674510356,0.089944503,DB1396110016322_,2.408562435,0.265048057,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,88791,DB10708,10019211,58,962,12,443,0.0112605,2.22472143,1.166985884,4.598555166,0.039126321,DB1070810019211_,3.24095988,0.799631708,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,flax seed,DB10708
,88792,DB00788,10020937,156,9200,42,5019,2.36841342359879e-05,2.02621494,1.430268408,2.926302111,0.000230698,DB0078810020937_,8.374402804,0.706169491,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,88794,DB00788,10024855,52,9304,25,5036,0.7197567,1.125829515,0.685172826,1.895830804,0.834604061,DB0078810024855_,0.180797845,0.118520111,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,88796,DB10708,10028813,64,956,15,440,0.017521848,1.962951819,1.091116036,3.751986174,0.055711058,DB1070810028813_,2.887576627,0.67444937,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,flax seed,DB10708
,88798,DB13961,10033557,72,9385,27,6387,0.007402488,1.814742277,1.149948599,2.941982621,0.028003011,DB1396110033557_,3.575443226,0.595943462,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,fish oil,DB13961
,88800,DB00169,10060800,257,38434,59,18116,1.18782150779574e-07,2.053160843,1.540928594,2.774581076,2.12393798179667e-06,DB0016910060800_,13.06223865,0.71938048,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,88802,DB13961,10060800,59,9398,10,6404,5.61409943839681e-06,4.020089977,2.037537265,8.822137583,6.54107286073849e-05,DB1396110060800_,9.634824267,1.391304285,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,fish oil,DB13961
,88805,DB00433,10000060,60,7596,45,5975,0.844006214,1.048802814,0.699618787,1.582161952,0.921081286,DB0043310000060_,0.082206988,0.047649336,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,88806,DB00437,10000060,60,6861,87,11459,0.394069724,1.151823042,0.813670395,1.621316536,0.564014304,DB0043710000060_,0.572675666,0.141345941,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,88816,DB00316,10013442,31,65443,30,36923,0.044432488,0.582980395,0.341319105,0.997147791,0.114467114,DB0031610013442_,2.167467715,-0.53960172,NA,10013442,Disseminated intravascular coagulation,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,88836,DB00295,10015090,46,14617,47,9555,0.033513786,0.639813998,0.416334442,0.982698387,0.092382136,DB0029510015090_,2.381821647,-0.446577773,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,88837,DB00327,10015090,32,6106,31,4231,0.199529455,0.71531372,0.421945237,1.214034795,0.348492092,DB0032710015090_,1.054139741,-0.335034064,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydromorphone,DB00327
,88839,DB00433,10015090,59,7597,42,5978,0.687650189,1.105420093,0.730498647,1.685764769,0.811687484,DB0043310015090_,0.208639884,0.100225437,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,88840,DB00512,10015090,18,4719,32,5066,0.089916657,0.603894873,0.318690643,1.11053132,0.195093427,DB0051210015090_,1.634276722,-0.504355148,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vancomycin,DB00512
,88846,DB01109,10015090,35,4377,28,4242,0.527517322,1.211417886,0.714570255,2.071263942,0.685085739,DB0110910015090_,0.378211283,0.19179148,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,heparin,DB01109
,88851,DB00646,10016288,67,3386,51,1949,0.147524331,0.756246111,0.515182272,1.11581437,0.280533698,DB0064610016288_,1.271061428,-0.279388413,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,nystatin,DB00646
,88856,DB01005,10016288,22,1073,31,836,0.035943116,0.553105041,0.302709537,0.994789545,0.09741852,DB0100510016288_,2.328738943,-0.592207348,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,hydroxyurea,DB01005
,88859,DB00186,10021143,124,16777,126,9882,2.3177913942183e-05,0.579710043,0.448124308,0.749759525,0.000226606,DB0018610021143_,8.392295701,-0.545227226,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,88860,DB00281,10021143,71,11387,72,5599,2.25110112202668e-05,0.484881746,0.343816685,0.683733341,0.000221032,DB0028110021143_,8.417204311,-0.72385024,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,88863,DB00433,10021143,58,7598,56,5964,0.297517977,0.812993396,0.552388229,1.197305588,0.463431396,DB0043310021143_,0.769096918,-0.207032293,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,88864,DB00512,10021143,75,4662,92,5006,0.434922071,0.875382974,0.634816014,1.203894258,0.603339379,DB0051210021143_,0.505275424,-0.133093804,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vancomycin,DB00512
,88865,DB00646,10021143,30,3423,28,1972,0.074763294,0.617339735,0.355237246,1.075746128,0.169468195,DB0064610021143_,1.775090012,-0.482335782,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nystatin,DB00646
,88867,DB00987,10021143,55,2049,74,2854,0.856875454,1.035256857,0.713209974,1.494962566,0.931317629,DB0098710021143_,0.07115489,0.034649567,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cytarabine,DB00987
,88869,DB01109,10021143,63,4349,64,4206,0.789334398,0.951995374,0.659690957,1.373535532,0.885855574,DB0110910021143_,0.12120135,-0.049195104,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,heparin,DB01109
,88870,DB01413,10021143,47,1173,54,1605,0.412909264,1.190837733,0.781948554,1.808057716,0.582306517,DB0141310021143_,0.540758309,0.174657037,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cefepime,DB01413
,88873,DB00281,10030124,97,11361,52,5619,0.662228967,0.922600743,0.651064197,1.320359459,0.79404641,DB0028110030124_,0.230613368,-0.080558703,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,88875,DB00646,10030124,55,3398,34,1966,0.824599862,0.935943329,0.597089141,1.486066012,0.907096084,DB0064610030124_,0.097506898,-0.066200351,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,88877,DB00736,10030124,136,10455,81,5472,0.387962743,0.878783814,0.661221112,1.174189162,0.558008246,DB0073610030124_,0.583381539,-0.129216357,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,88880,DB01109,10030124,69,4343,31,4239,0.000259839,2.172311364,1.399285441,3.441762843,0.001793794,DB0110910030124_,6.323422359,0.775791746,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,88903,DB00281,10043071,73,11385,78,5593,3.11833281870649e-06,0.459783813,0.328948031,0.642052074,3.91803910801625e-05,DB0028110043071_,10.14733416,-0.776998872,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,lidocaine,DB00281
,88904,DB00327,10043071,44,6094,52,4210,0.009106533,0.58460663,0.381427133,0.892407479,0.033038678,DB0032710043071_,3.410076351,-0.536816085,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,hydromorphone,DB00327
,88910,DB00683,10043071,67,1517,36,1602,0.001251612,1.964974136,1.283060391,3.053012621,0.006619729,DB0068310043071_,5.017700901,0.675479083,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,midazolam,DB00683
,88913,DB01109,10043071,41,4371,82,4188,0.000118039,0.479109032,0.320195097,0.707144123,0.000919581,DB0110910043071_,6.991592316,-0.735827084,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,heparin,DB01109
,88933,DB00953,10027599,138,1559,16,216,0.605720189,1.194891818,0.693412653,2.191260091,0.748782165,DB0095310027599_,0.289307173,0.178055652,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,rizatriptan,DB00953
,88939,DB00575,10008479,82,5162,63,3766,0.799425129,0.94961864,0.673517646,1.344185051,0.891654641,DB0057510008479_,0.114676396,-0.051694807,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,88942,DB00695,10034474,171,27878,99,20429,0.063955613,1.265738809,0.981824036,1.639215506,0.150573093,DB0069510034474_,1.893306646,0.23565599,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,furosemide,DB00695
,88943,DB01136,10034474,46,9838,32,11083,0.040389335,1.61936258,1.008325449,2.630008468,0.10641506,DB0113610034474_,2.240408173,0.482032603,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,carvedilol,DB01136
,88948,DB14500,10048294,30,7779,23,4050,0.191131738,0.67908504,0.380845164,1.225955226,0.338002336,DB1450010048294_,1.084702472,-0.387008917,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,potassium,DB14500
,88985,DB00370,10011906,286,4255,282,3381,0.014246909,0.805891262,0.676958619,0.959390229,0.047238097,DB0037010011906_,3.052554576,-0.215806456,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,88987,DB00091,10012735,244,5266,76,2594,0.000507034,1.581404096,1.212096905,2.08291803,0.003123726,DB0009110012735_,5.768728864,0.458313121,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cyclosporine,DB00091
,88989,DB00887,10012735,157,2184,78,1737,0.000878288,1.600676784,1.203035999,2.14403459,0.004951907,DB0088710012735_,5.307982525,0.47042653,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,bumetanide,DB00887
,88990,DB00635,10013710,222,32831,315,23479,4.17420767867779e-15,0.504006929,0.422204821,0.600901881,2.59383094170321e-13,DB0063510013710_,28.9804703,-0.685165263,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,88993,DB01068,10013710,146,13617,127,6713,5.16026025778976e-06,0.566739451,0.442872531,0.726057568,6.09059007076802e-05,DB0106810013710_,9.706180496,-0.567855603,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,88994,DB01394,10013710,25,1415,59,1944,0.02490574,0.58222905,0.347578508,0.949534553,0.073271855,DB0139410013710_,2.613578715,-0.540891352,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,colchicine,DB01394
,88997,DB00451,10018627,94,47177,52,15367,0.002769853,0.58882726,0.415084547,0.843332293,0.012661841,DB0045110018627_,4.369162485,-0.529622416,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,88998,DB00497,10018627,21,19246,34,16341,0.020923567,0.524434751,0.28911943,0.930384736,0.064054479,DB0049710018627_,2.74802133,-0.645434262,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,88999,DB00635,10018627,57,32996,103,23691,1.13984545365156e-08,0.397342296,0.282209629,0.554657789,2.53475784680467e-07,DB0063510018627_,15.18799754,-0.922957164,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,89009,DB00091,10033661,38,5472,32,2638,0.021392459,0.572510361,0.347423659,0.948936795,0.065205635,DB0009110033661_,2.73020938,-0.557724447,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,cyclosporine,DB00091
,89015,DB00091,10070863,36,5474,26,2644,0.134329121,0.668804783,0.391843006,1.156199555,0.261747355,DB0009110070863_,1.340375533,-0.402263065,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclosporine,DB00091
,89017,DB00887,10070863,51,2290,13,1802,0.000108862,3.086248897,1.648280104,6.2049113,0.000857614,DB0088710070863_,7.061356784,1.126956404,female,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,bumetanide,DB00887
,89018,DB06643,10028997,84,52337,13,7502,0.759064465,0.926177778,0.513054597,1.812305908,0.865634494,DB0664310028997_,0.144292522,-0.076689078,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,denosumab,DB06643
,89029,DB00722,10013654,29,25374,45,25987,0.081961,0.660021765,0.398917885,1.07633306,0.181632652,DB0072210013654_,1.705769028,-0.415482467,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,89041,DB00722,10047531,56,25347,37,25995,0.038113081,1.552183814,1.006341273,2.41957853,0.101824701,DB0072210047531_,2.284502558,0.439662852,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,lisinopril,DB00722
,89052,DB01015,10022595,31,9856,36,9345,0.463039445,0.816475792,0.487957073,1.358879272,0.630182947,DB0101510022595_,0.46174511,-0.202758016,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,89074,DB00422,10002368,15,3420,43,2906,1.65326991941304e-05,0.296462619,0.152677726,0.545703968,0.000168828,DB0042210002368_,8.686633044,-1.215834143,male,10002368,Anger,10037175,Psychiatric disorders,Psych,methylphenidate,DB00422
,89075,DB01373,10005555,40,22680,13,7368,1,0.999614836,0.523391341,2.038097368,1,DB0137310005555_,0,-0.000385238,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,calcium,DB01373
,89077,DB00335,10017944,36,8430,21,5444,0.786437745,1.107078812,0.628306014,1.998069754,0.88414144,DB0033510017944_,0.12313823,0.101724845,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,atenolol,DB00335
,89078,DB00451,10017944,222,47049,51,15368,0.023983822,1.421803996,1.044006292,1.968692209,0.071205147,DB0045110017944_,2.642190168,0.351926485,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,89079,DB00335,10022086,79,8387,27,5438,0.003606156,1.897040118,1.209931801,3.059667093,0.015692048,DB0033510022086_,4.154601174,0.640294839,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,89093,DB00451,10062189,65,47206,15,15404,0.24481178,1.41399857,0.797329303,2.670710935,0.403568207,DB0045110062189_,0.907409766,0.346421556,NA,10062189,Vitamin D decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,89097,DB06273,10013968,169,4926,32,1378,0.045382013,1.477273086,1.002377184,2.239445371,0.116314777,DB0627310013968_,2.151455166,0.390197879,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tocilizumab,DB06273
,89100,DB00451,10003553,239,47032,28,15391,7.94578604161317e-09,2.793359662,1.883050871,4.295037858,1.82485789518394e-07,DB0045110003553_,15.51659353,1.027245051,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,89101,DB00451,10040753,787,46484,124,15295,2.4110431821162e-16,2.088423848,1.72436965,2.546978083,1.7268193471914e-14,DB0045110040753_,31.68991011,0.736409642,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,89102,DB01175,10040753,145,10579,27,4865,3.01910143253446e-06,2.469572626,1.626617661,3.88067565,3.80974945531292e-05,DB0117510040753_,10.17536204,0.90404511,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,escitalopram,DB01175
,89112,DB00996,10029412,77,38876,63,22362,0.042986909,0.703068001,0.49718897,0.997367245,0.111656793,DB0099610029412_,2.192325462,-0.352301662,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,89126,DB00950,10013709,215,4503,86,1970,0.52166488,1.093698694,0.84280516,1.429486925,0.680376182,DB0095010013709_,0.385109425,0.089565249,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,89141,DB06285,10037087,132,8718,17,1089,0.895337651,0.969918255,0.580488497,1.721903905,0.95615204,DB0628510037087_,0.044838341,-0.030543484,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,teriparatide,DB06285
,89147,DB01229,10042772,73,5668,35,2674,0.917744818,0.983981883,0.647196612,1.521542644,0.963471694,DB0122910042772_,0.03721217,-0.016147794,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,paclitaxel,DB01229
,89149,DB00863,10024855,80,10593,35,5805,0.283118436,1.252603532,0.830910976,1.92313473,0.447436754,DB0086310024855_,0.804220082,0.225224211,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,89169,DB00542,10047700,55,1631,26,1398,0.012776732,1.812849596,1.110780373,3.028696547,0.043280676,DB0054210047700_,3.140049024,0.59489997,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,benazepril,DB00542
,89172,DB00514,10013710,46,2120,21,1515,0.103573764,1.56518164,0.910941872,2.773388326,0.216392984,DB0051410013710_,1.530659155,0.448001881,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,dextromethorphan,DB00514
,89184,DB14726,10019211,42,1975,37,2811,0.037974427,1.615424682,1.009429203,2.595033406,0.101572994,DB1472610019211_,2.286977586,0.479597883,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,dabigatran,DB14726
,89189,DB00341,10033645,36,11369,14,5054,0.760030158,1.143093521,0.601053527,2.296279325,0.866547788,DB0034110033645_,0.143238021,0.133738202,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,89193,DB06605,10048294,65,14008,47,12986,0.218041371,1.282064881,0.866717166,1.909094528,0.371223827,DB0660510048294_,0.990950092,0.248471967,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,apixaban,DB06605
,89202,DB01175,10052904,54,10670,20,4872,0.454045311,1.232800641,0.725056096,2.176993228,0.621544202,DB0117510052904_,0.475548249,0.209288525,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,89206,DB00682,10067383,36,19423,36,16328,0.479187419,0.840659011,0.514447814,1.37371341,0.644343448,DB0068210067383_,0.43952339,-0.173569158,NA,10067383,Abdominal wall haematoma,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,89207,DB01225,10067383,40,5004,39,4601,0.821759473,0.943018962,0.590178636,1.508002162,0.905088948,DB0122510067383_,0.099722055,-0.058668888,NA,10067383,Abdominal wall haematoma,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,89214,DB08816,10053762,52,1099,73,1829,0.396431482,1.185409854,0.807605148,1.729708797,0.566027084,DB0881610053762_,0.56911335,0.170088583,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ticagrelor,DB08816
,89220,DB00588,10016454,47,16477,10,8458,0.007647705,2.412538723,1.202348601,5.357658694,0.028733553,DB0058810016454_,3.549689755,0.880679605,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,89246,DB00222,10037844,82,3124,68,3060,0.322564491,1.1811457,0.842449974,1.660480072,0.49087681,DB0022210037844_,0.711562079,0.1664849,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,glimepiride,DB00222
,89248,DB06616,10037844,87,874,55,748,0.095391566,1.353543255,0.940436978,1.9615749,0.203854955,DB0661610037844_,1.590346544,0.302725788,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,bosutinib,DB06616
,89249,DB08882,10013573,47,950,28,965,0.033488507,1.704613457,1.035726658,2.852348598,0.092331819,DB0888210013573_,2.382366464,0.533338373,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,linagliptin,DB08882
,89251,DB00829,10003658,42,8010,30,4424,0.323329722,0.773268458,0.471856546,1.281438824,0.491759554,DB0082910003658_,0.709765394,-0.257128997,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,diazepam,DB00829
,89289,DB01409,10010774,83,5948,65,3901,0.309872348,0.837491337,0.596433253,1.180275645,0.477323796,DB0140910010774_,0.7395602,-0.177344359,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,tiotropium,DB01409
,89290,DB00758,10028411,95,8205,123,9951,0.681379238,0.936700182,0.707863459,1.236402716,0.807399032,DB0075810028411_,0.21393727,-0.065392024,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,clopidogrel,DB00758
,89292,DB00787,10017955,42,16958,56,17192,0.189351314,0.760357353,0.496888551,1.155627811,0.335734715,DB0078710017955_,1.091433968,-0.273966755,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,89293,DB01373,10017955,101,22619,51,7330,0.013589857,0.641784288,0.45343341,0.918233307,0.04545516,DB0137310017955_,3.091028924,-0.443503032,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,89302,DB09072,10003553,89,6382,16,2519,0.002175779,2.195382303,1.2771759,4.014679832,0.010429533,DB0907210003553_,4.563113799,0.786356201,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium oxybate,DB09072
,89308,DB09072,10048959,53,6418,14,2521,0.219941782,1.487036069,0.81154554,2.907463766,0.373352045,DB0907210048959_,0.985233484,0.396784924,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,89312,DB00065,10041101,52,9412,53,4904,0.000869453,0.511215447,0.341353087,0.765353713,0.00491052,DB0006510041101_,5.316375412,-0.670964159,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,infliximab,DB00065
,89330,DB00190,10041349,134,3163,211,4463,0.342485128,0.896070633,0.712675856,1.123631727,0.511798139,DB0019010041349_,0.669824991,-0.109736037,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,89331,DB00363,10041349,43,4585,45,6843,0.102050209,1.426067102,0.915065058,2.219946494,0.214034688,DB0036310041349_,1.541617182,0.354920377,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,clozapine,DB00363
,89333,DB00190,10047899,41,3256,26,4648,0.001114848,2.250873945,1.341275867,3.84042743,0.006022769,DB0019010047899_,5.112208198,0.811318561,NA,10047899,Weight increased,10022891,Investigations,Inv,carbidopa,DB00190
,89334,DB00268,10047899,77,2898,25,1520,0.04426121,1.615301005,1.01214239,2.659334043,0.114120938,DB0026810047899_,2.170496531,0.47952132,NA,10047899,Weight increased,10022891,Investigations,Inv,ropinirole,DB00268
,89346,DB01104,10060800,74,15389,14,7272,0.000812278,2.497654223,1.397705469,4.793044177,0.004636424,DB0110410060800_,5.373811918,0.915351981,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,sertraline,DB01104
,89347,DB00203,10003662,65,13813,40,8898,0.841974768,1.046788066,0.694674962,1.594748971,0.919494237,DB0020310003662_,0.083931503,0.045726491,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,sildenafil,DB00203
,89350,DB00374,10003662,64,17652,28,5696,0.181768632,0.737571591,0.465684949,1.195870165,0.326151169,DB0037410003662_,1.120394295,-0.304392123,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,treprostinil,DB00374
,89351,DB00559,10003662,53,9606,19,3287,0.892183385,0.954507846,0.554877145,1.70999923,0.955096007,DB0055910003662_,0.045943412,-0.046559416,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,bosentan,DB00559
,89352,DB00695,10003662,77,27972,64,20464,0.494760597,0.880196772,0.623256659,1.246674361,0.657228907,DB0069510003662_,0.419722909,-0.127609793,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,furosemide,DB00695
,89353,DB00722,10003662,18,25385,53,25979,4.19444459842424e-05,0.347550605,0.191535332,0.603196213,0.000380045,DB0072210003662_,7.875221601,-1.056844999,male,10003662,Atrial flutter,10007541,Cardiac disorders,Card,lisinopril,DB00722
,89355,DB00215,10016807,52,11051,16,5260,0.152047774,1.546880939,0.868377345,2.905503848,0.286806023,DB0021510016807_,1.24894917,0.436240606,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,citalopram,DB00215
,89357,DB00758,10016807,90,8210,62,10012,0.000553784,1.770144495,1.265019818,2.490927256,0.003359385,DB0075810016807_,5.695997341,0.571061179,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,clopidogrel,DB00758
,89358,DB00203,10019304,56,13822,21,8917,0.034974598,1.720308527,1.024487163,2.993532491,0.095372127,DB0020310019304_,2.349968916,0.542503651,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,sildenafil,DB00203
,89360,DB00374,10019304,72,17644,14,5710,0.079439008,1.664255836,0.929694706,3.19817894,0.177495267,DB0037410019304_,1.728811337,0.509378078,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,treprostinil,DB00374
,89361,DB00559,10019304,46,9613,13,3293,0.653668707,1.212101178,0.642877404,2.448680544,0.787749099,DB0055910019304_,0.238575642,0.192355365,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,bosentan,DB00559
,89362,DB00215,10021143,46,11057,28,5248,0.318958209,0.779791312,0.47655221,1.297072708,0.487091362,DB0021510021143_,0.719303572,-0.248728944,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,89367,DB00695,10024690,69,27980,44,20484,0.505472204,1.148023793,0.775033271,1.716614621,0.666365919,DB0069510024690_,0.405916332,0.138042023,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,furosemide,DB00695
,89368,DB00758,10048959,170,8130,129,9945,4.96708036167462e-05,1.611966108,1.272200052,2.046564747,0.000439299,DB0075810048959_,7.730329942,0.477454619,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,89374,DB00682,10072268,18,19441,36,16328,0.002371948,0.419945234,0.224414965,0.759462752,0.011181252,DB0068210072268_,4.493516845,-0.867630971,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,warfarin,DB00682
,89378,DB06655,10005557,101,3587,74,2045,0.111033055,0.778179659,0.567869927,1.07048275,0.227643528,DB0665510005557_,1.479974348,-0.250797858,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,liraglutide,DB06655
,89379,DB01267,10043414,61,2791,125,3590,0.003327388,0.62774735,0.452556135,0.862971098,0.014707622,DB0126710043414_,4.219389409,-0.465617502,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,89383,DB00996,10033647,35,38918,32,22393,0.07461329,0.629366572,0.378281311,1.050295335,0.169193833,DB0099610033647_,1.776710281,-0.463041407,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,89384,DB00999,10033647,68,21362,45,12194,0.435212967,0.862591967,0.582870168,1.287395894,0.603657715,DB0099910033647_,0.504747939,-0.147813507,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,89391,DB01073,10011831,39,1026,57,1593,0.831577544,1.062302626,0.682746828,1.637979319,0.912004663,DB0107310011831_,0.092110176,0.060438841,NA,10011831,Cytomegalovirus infection,10021881,Infections and infestations,Infec,fludarabine,DB01073
,89409,DB00722,10019708,28,25375,30,26002,0.896076563,0.956383741,0.550435483,1.657088254,0.956301489,DB0072210019708_,0.044682051,-0.044596043,NA,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,lisinopril,DB00722
,89411,DB00999,10019708,37,21393,18,12221,0.674342266,1.174231006,0.651487927,2.192033765,0.802491104,DB0099910019708_,0.22003451,0.160613471,NA,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,hydrochlorothiazide,DB00999
,89414,DB00909,10028813,52,768,16,465,0.019806143,1.966842478,1.090092446,3.735528427,0.061315012,DB0090910028813_,2.791730565,0.676429454,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,zonisamide,DB00909
,89417,DB00982,10003239,149,3215,107,1994,0.263775459,0.863695402,0.664813435,1.125071338,0.425619272,DB0098210003239_,0.854210061,-0.146535116,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,isotretinoin,DB00982
,89418,DB00181,10029354,30,9826,21,5850,0.565147685,0.8505281,0.470492168,1.564616093,0.716814577,DB0018110029354_,0.332938081,-0.161897828,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,baclofen,DB00181
,89419,DB00281,10029354,89,11369,42,5629,0.852414981,1.049175904,0.718015996,1.554753225,0.927730502,DB0028110029354_,0.075013996,0.048005002,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,lidocaine,DB00281
,89420,DB00341,10029354,74,11331,41,5027,0.265117619,0.800772289,0.538707739,1.204963873,0.427074809,DB0034110029354_,0.850796085,-0.222178655,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,cetirizine,DB00341
,89421,DB00437,10029354,101,6820,159,11387,0.651900335,1.060590155,0.816620844,1.372196316,0.78617341,DB0043710029354_,0.240577888,0.058825503,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,allopurinol,DB00437
,89422,DB00722,10029354,131,25272,139,25893,0.807248722,0.965597068,0.754226817,1.235680925,0.895882651,DB0072210029354_,0.109945845,-0.035008646,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,lisinopril,DB00722
,89423,DB00924,10029354,54,10108,38,4213,0.015713822,0.592316333,0.383337376,0.92354146,0.051121703,DB0092410029354_,2.973546158,-0.523714441,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,cyclobenzaprine,DB00924
,89424,DB01067,10029354,24,4337,36,4787,0.299469312,0.735864921,0.419255069,1.270215347,0.465459948,DB0106710029354_,0.764729226,-0.306708708,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,glipizide,DB01067
,89425,DB01076,10029354,130,25617,183,25400,0.002600981,0.704372995,0.557748486,0.887399728,0.012031195,DB0107610029354_,4.420252432,-0.35044724,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,atorvastatin,DB01076
,89427,DB11089,10029354,137,10038,126,8281,0.383228453,0.896991954,0.697792012,1.1538563,0.553303116,DB1108910029354_,0.591849297,-0.108708387,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,docusate,DB11089
,89442,DB00921,10074903,67,5778,92,4811,0.002209592,0.606416405,0.434850385,0.841926055,0.010550251,DB0092110074903_,4.551605597,-0.500188391,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,buprenorphine,DB00921
,89443,DB08931,10037423,123,6454,28,2418,0.016230227,1.645758991,1.081298077,2.58472532,0.0524286,DB0893110037423_,2.948303042,0.498201671,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,89447,DB00005,10060968,82,128000,25,42394,0.823016926,1.086345243,0.686856537,1.77504503,0.906059659,DB0000510060968_,0.098650126,0.082819075,NA,10060968,Arthritis infective,10021881,Infections and infestations,Infec,etanercept,DB00005
,89453,DB00230,10033557,118,19556,15,8636,2.1434416411483e-07,3.473510971,2.021315009,6.406986528,3.60693748640096e-06,DB0023010033557_,12.53265149,1.24516589,female,10033557,Palpitations,10007541,Cardiac disorders,Card,pregabalin,DB00230
,89454,DB00230,10054236,46,19628,7,8644,0.004408098,2.893831468,1.297061718,7.600296111,0.018475141,DB0023010054236_,3.991329205,1.062581391,female,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,pregabalin,DB00230
,89467,DB00264,10013578,29,29578,34,24858,0.206309536,0.716840991,0.421180792,1.212697935,0.356836623,DB0026410013578_,1.030477241,-0.332901233,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,89468,DB00722,10013578,24,25379,32,26000,0.351442618,0.768357681,0.432929255,1.346562514,0.521152063,DB0072210013578_,0.651713412,-0.263499924,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,89469,DB01076,10013578,25,25722,35,25548,0.198468574,0.709461703,0.406907956,1.220059812,0.347239407,DB0107610013578_,1.057740802,-0.343248762,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,89480,DB08901,10019211,41,466,31,549,0.086464779,1.557489544,0.936395126,2.613529547,0.189141704,DB0890110019211_,1.66525879,0.443075258,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ponatinib,DB08901
,89487,DB00722,10026865,35,25368,17,26015,0.011876124,2.11129123,1.151214399,4.019987344,0.040835099,DB0072210026865_,3.198213298,0.747299718,NA,10026865,Mass,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,89501,DB00264,10038063,102,29505,129,24763,0.002262737,0.663630308,0.506460394,0.867672335,0.010756134,DB0026410038063_,4.532279126,-0.41003005,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,89537,DB00588,10001760,180,16344,21,8447,1.58993812987744e-14,4.429262345,2.809149205,7.337544869,9.11483614914473e-13,DB0058810001760_,27.72370278,1.488233057,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,89540,DB00588,10069868,58,16466,19,8449,0.092187648,1.566333864,0.91859328,2.787111819,0.198716774,DB0058810069868_,1.615874715,0.44873777,NA,10069868,Device issue,10077536,Product issues,Prod,fluticasone propionate,DB00588
,89541,DB01097,10003285,51,6214,10,1493,0.628856122,1.225314012,0.613245966,2.713570894,0.768014613,DB0109710003285_,0.263946519,0.203197148,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,89542,DB01281,10003285,78,8854,13,1785,0.67182278,1.209601852,0.665937988,2.377902357,0.800827851,DB0128110003285_,0.222109273,0.190291258,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,abatacept,DB01281
,89543,DB01097,10006451,83,6182,17,1486,0.611952913,1.173572876,0.688110471,2.116773385,0.753881017,DB0109710006451_,0.282520726,0.160052836,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,leflunomide,DB01097
,89544,DB01281,10006451,124,8808,29,1769,0.446223065,0.858803112,0.56732488,1.339436247,0.61405022,DB0128110006451_,0.487678562,-0.152215589,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,abatacept,DB01281
,89545,DB01097,10025482,160,6105,28,1475,0.134382736,1.380541211,0.915554884,2.152015897,0.261793909,DB0109710025482_,1.340197693,0.322475604,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,89546,DB01281,10028813,301,8631,38,1760,0.004855989,1.615156192,1.144927479,2.336429818,0.019990551,DB0128110028813_,3.912495577,0.479431665,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,abatacept,DB01281
,89547,DB00203,10001053,188,13690,98,8840,0.088201725,1.238710498,0.963758401,1.600397285,0.192261254,DB0020310001053_,1.648900133,0.214070917,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,89556,DB00668,10037377,31,10060,22,4281,0.071424869,0.599657306,0.335739859,1.088310551,0.163736498,DB0066810037377_,1.809496863,-0.511396943,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,89557,DB00741,10037377,31,4063,28,3146,0.599002681,0.857286436,0.49638763,1.48668847,0.743713444,DB0074110037377_,0.296099475,-0.153983186,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrocortisone,DB00741
,89558,DB00927,10037377,61,7436,55,4961,0.106733192,0.739971859,0.504524179,1.087419445,0.221227309,DB0092710037377_,1.508564558,-0.301143122,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,89566,DB01050,10054889,33,18075,33,9338,0.0088322,0.516620881,0.308864867,0.864222489,0.032230235,DB0105010054889_,3.434850292,-0.66044598,NA,10054889,Transaminases increased,10022891,Investigations,Inv,ibuprofen,DB01050
,89603,DB01216,10011224,8,228,122,6993,0.071216707,2.010953058,0.838810346,4.157238885,0.163401811,DB0121610011224_,1.811543012,0.698608768,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,finasteride,DB01216
,89613,DB00497,10001949,80,19187,57,16318,0.344880555,1.193637813,0.838675253,1.708378058,0.51432217,DB0049710001949_,0.664905421,0.177005629,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,89616,DB00230,10005555,41,19633,15,8636,0.66324316,1.202294362,0.651153986,2.339708821,0.794754916,DB0023010005555_,0.229721493,0.1842317,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,pregabalin,DB00230
,89617,DB00497,10005555,30,19237,29,16346,0.695311555,0.879021493,0.509556722,1.518452553,0.816560818,DB0049710005555_,0.202653883,-0.12894593,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,oxycodone,DB00497
,89629,DB00497,10020937,211,19056,135,16240,0.009277657,1.331983348,1.067017107,1.667433637,0.03351611,DB0049710020937_,3.395729051,0.286669071,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,89630,DB00814,10020937,142,8145,44,3371,0.103817537,1.335608797,0.943833293,1.923021424,0.216729724,DB0081410020937_,1.529104211,0.289387215,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,89631,DB01156,10020937,149,13473,37,6291,0.00034899,1.880302763,1.302496483,2.776936143,0.002288438,DB0115610020937_,6.079885593,0.631432808,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,89633,DB01156,10028245,48,13574,17,6311,0.42304241,1.312684576,0.74072487,2.436930036,0.591928336,DB0115610028245_,0.524369706,0.272074335,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,89635,DB00451,10029202,43,47228,11,15408,0.530663521,1.275315671,0.646521598,2.743022041,0.687659764,DB0045110029202_,0.374461092,0.243193733,NA,10029202,Nervous system disorder,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,89641,DB00736,10041349,113,10478,48,5505,0.24320053,1.236790514,0.873446519,1.774790025,0.401553185,DB0073610041349_,0.912415289,0.212519729,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,89642,DB00814,10041349,119,8168,39,3376,0.218801614,1.261109866,0.869559638,1.864535902,0.372043035,DB0081410041349_,0.988745746,0.231992179,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,89644,DB00230,10052897,73,19601,37,8614,0.469585488,0.867072333,0.575627948,1.326047357,0.635912136,DB0023010052897_,0.452694876,-0.142632877,NA,10052897,Nerve injury,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,89646,DB00497,10052897,34,19233,16,16359,0.0638173,1.807425942,0.970392494,3.508042765,0.150348456,DB0049710052897_,1.894799639,0.591903702,NA,10052897,Nerve injury,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,89650,DB00422,10000081,43,3392,25,2924,0.141852411,1.482595496,0.88284064,2.539712971,0.272338808,DB0042210000081_,1.30070837,0.393794265,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,methylphenidate,DB00422
,89651,DB01115,10000081,61,3539,21,2247,0.016040927,1.844126493,1.103492738,3.198176629,0.051919192,DB0111510000081_,2.958066764,0.61200572,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,nifedipine,DB01115
,89655,DB01050,10001551,61,18047,58,9313,0.00127436,0.542723027,0.372245835,0.792097815,0.006714083,DB0105010001551_,5.003547986,-0.611156168,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,ibuprofen,DB01050
,89661,DB01050,10003481,61,18047,54,9317,0.004212412,0.583177037,0.397301352,0.858069874,0.017815488,DB0105010003481_,4.027687069,-0.539264474,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,ibuprofen,DB01050
,89665,DB01050,10006093,42,18066,28,9343,0.313372966,0.77576857,0.469321149,1.300446256,0.480908945,DB0105010006093_,0.73207733,-0.253901038,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,ibuprofen,DB01050
,89666,DB01115,10006093,45,3555,58,2210,0.000310236,0.482376359,0.318166092,0.727326299,0.002074422,DB0111510006093_,6.178072487,-0.729030641,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,nifedipine,DB01115
,89669,DB01115,10021097,120,3480,81,2187,0.65845309,0.931046575,0.692785717,1.256525964,0.791450497,DB0111510021097_,0.233887945,-0.071445976,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,nifedipine,DB01115
,89670,DB01238,10021097,56,5194,30,3472,0.376611848,1.247758918,0.785307709,2.018497519,0.546421352,DB0123810021097_,0.604364893,0.221349077,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,aripiprazole,DB01238
,89675,DB01238,10022524,30,5220,29,3473,0.181950447,0.688314469,0.398418852,1.190819538,0.326321473,DB0123810022524_,1.11987227,-0.373509468,NA,10022524,Intentional self-injury,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,89683,DB00422,10033295,20,3415,40,2909,0.001624749,0.425968588,0.235355512,0.748038733,0.008199392,DB0042210033295_,4.803695277,-0.853389672,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,methylphenidate,DB00422
,89685,DB00422,10047700,122,3313,87,2862,0.181002621,1.211366158,0.908151803,1.621367165,0.3251096,DB0042210047700_,1.123592923,0.191748779,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,methylphenidate,DB00422
,89692,DB00193,10041349,285,19035,83,8619,0.000339511,1.554764043,1.211823861,2.012980965,0.002236042,DB0019310041349_,6.10304809,0.441323793,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,89705,DB06637,10011906,75,6087,53,1966,2.85213792691799e-05,0.457095874,0.316049649,0.665160595,0.000271428,DB0663710011906_,8.211813223,-0.782862121,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,89710,DB08865,10012174,20,1191,32,939,0.01571189,0.492912732,0.265305698,0.895248559,0.051118584,DB0886510012174_,2.973607168,-0.707423136,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,crizotinib,DB08865
,89726,DB00169,10010254,42,38649,10,18165,0.052897283,1.973975768,0.974353613,4.413153815,0.13048708,DB0016910010254_,2.036481059,0.680049665,NA,10010254,Concussion,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,89731,DB00169,10011985,36,38655,21,18154,0.477423958,0.805125191,0.457342637,1.451915642,0.642759952,DB0016910011985_,0.441983949,-0.216757497,NA,10011985,Decubitus ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,89732,DB00060,10015150,53,9455,13,2452,1,1.057306161,0.567465359,2.117729313,1,DB0006010015150_,0,0.055724316,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,interferon beta-1a,DB00060
,89735,DB00060,10020100,48,9460,7,2458,0.18107144,1.781594971,0.800198699,4.672274027,0.325199877,DB0006010020100_,1.123315279,0.577509014,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,interferon beta-1a,DB00060
,89736,DB00169,10020100,165,38526,56,18119,0.035954781,1.385746519,1.017021171,1.91256145,0.097425022,DB0016910020100_,2.328672198,0.326238998,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,89740,DB00169,10023424,71,38620,26,18149,0.32667463,1.283245603,0.808185656,2.096660515,0.495078566,DB0016910023424_,0.70303881,0.249392496,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,89742,DB00169,10024453,64,38627,7,18168,1.79839615044617e-05,4.300659377,1.970538172,11.12509096,0.000181881,DB0016910024453_,8.612158546,1.458768354,female,10024453,Ligament sprain,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,89744,DB00169,10025197,96,38595,31,18144,0.070536631,1.45583177,0.961726842,2.259777396,0.162245053,DB0016910025197_,1.818647416,0.375577401,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,89746,DB00169,10025282,47,38644,11,18164,0.034431706,2.008305962,1.026337174,4.29494734,0.094269817,DB0016910025282_,2.361594211,0.697291562,NA,10025282,Lymphoedema,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,89749,DB00169,10039227,59,38632,15,18160,0.033426716,1.848950056,1.035292644,3.510370512,0.092195302,DB0016910039227_,2.383846108,0.614617941,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,89750,DB00169,10039580,39,38652,14,18161,0.462021236,1.308837819,0.695023597,2.610492868,0.629185721,DB0016910039580_,0.463328802,0.269139583,NA,10039580,Scar,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,89751,DB00169,10039722,48,38643,7,18168,0.00134261,3.223738391,1.449974994,8.4466702,0.0070167,DB0016910039722_,4.959462254,1.170541677,female,10039722,Scoliosis,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,89756,DB00169,10046555,63,38628,60,18115,0.000135821,0.492400156,0.340075161,0.713634979,0.001035398,DB0016910046555_,6.872969082,-0.708463567,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,89760,DB00169,10052428,74,38617,33,18142,0.836458222,1.053474017,0.689808462,1.640288405,0.915542875,DB0016910052428_,0.088238083,0.05209329,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,89761,DB00060,10052904,61,9447,27,2438,0.023931388,0.583081302,0.364095869,0.95644803,0.071081591,DB0006010052904_,2.643926899,-0.539428648,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,interferon beta-1a,DB00060
,89762,DB00169,10055798,149,38542,83,18092,0.230289297,0.842691852,0.639630765,1.116582612,0.386265278,DB0016910055798_,0.951230898,-0.171153926,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,89765,DB01240,10041349,61,5690,14,1562,0.671628676,1.19607835,0.659211116,2.321956438,0.800757065,DB0124010041349_,0.222197668,0.179048163,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,epoprostenol,DB01240
,89771,DB06616,10025482,46,915,28,775,0.190670066,1.391232301,0.842177613,2.335171979,0.337412912,DB0661610025482_,1.086447841,0.330189902,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,bosutinib,DB06616
,89781,DB01240,10037400,296,5455,86,1490,0.609403603,0.940124824,0.731704485,1.218045975,0.7518328,DB0124010037400_,0.28524132,-0.061742621,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,89782,DB00682,10052268,142,19317,21,16343,3.30268274091104e-19,5.720596148,3.60054037,9.532708209,3.19745914713984e-17,DB0068210052268_,37.9815901,1.744073022,female,10052268,Catheter site pain,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,89783,DB00559,10060933,69,9590,38,3268,0.019420226,0.618795213,0.409741676,0.947166647,0.06040597,DB0055910060933_,2.806667342,-0.479980896,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,89784,DB01240,10060933,69,5682,13,1563,0.278495553,1.459951582,0.797495313,2.886965542,0.442311517,DB0124010060933_,0.815740855,0.378403272,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,89794,DB00620,10000081,80,4748,32,3100,0.019257233,1.632169858,1.067719557,2.548896995,0.060019727,DB0062010000081_,2.813081994,0.489910331,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,triamcinolone,DB00620
,89829,DB00175,10003239,213,7918,102,6004,0.000137811,1.583399164,1.241574024,2.030026771,0.001048743,DB0017510003239_,6.860162994,0.459573906,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,89830,DB00706,10003239,24,1051,232,15693,0.051202255,1.544570802,0.965332073,2.36893067,0.127303375,DB0070610003239_,2.061182263,0.434746074,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tamsulosin,DB00706
,89832,DB01039,10003988,72,2901,50,3001,0.035111631,1.489530827,1.020100318,2.189799267,0.095642628,DB0103910003988_,2.347136661,0.398461189,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fenofibrate,DB01039
,89864,DB00264,10030095,223,29384,120,24772,6.81070034235275e-05,1.566639715,1.248465941,1.9738948,0.00057332,DB0026410030095_,7.464066039,0.448933017,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,89865,DB00295,10030095,52,14611,36,9566,0.827445316,0.945706177,0.606040667,1.490373927,0.909224901,DB0029510030095_,0.0951628,-0.055823353,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,89866,DB00575,10030095,30,5214,30,3799,0.238859755,0.728651113,0.42358414,1.253416292,0.396584034,DB0057510030095_,0.924867321,-0.316560245,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,89905,DB01268,10046571,46,2097,20,3110,1.82531634339634e-06,3.410272419,1.970724631,6.104675089,2.44476127827632e-05,DB0126810046571_,10.61897798,1.226792176,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,sunitinib,DB01268
,89913,DB00175,10062237,41,8090,29,6077,0.903763811,1.062012569,0.643372913,1.774136107,0.957417047,DB0017510062237_,0.043516196,0.060165758,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,pravastatin,DB00175
,89914,DB00264,10062237,131,29476,156,24736,0.003536888,0.70471653,0.553951263,0.895295395,0.015448173,DB0026410062237_,4.170264514,-0.349959642,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,89915,DB00316,10062237,168,65306,144,36809,0.000301732,0.657551012,0.523036962,0.827638997,0.0020271,DB0031610062237_,6.201149095,-0.419232933,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,89917,DB00433,10062237,40,7616,33,5987,0.906020974,0.95283442,0.585128009,1.561306692,0.958051345,DB0043310062237_,0.042853907,-0.048314136,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,prochlorperazine,DB00433
,89918,DB00497,10062237,62,19205,59,16316,0.583755941,0.892772537,0.614487831,1.298295509,0.731695711,DB0049710062237_,0.312390547,-0.113423449,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,oxycodone,DB00497
,89919,DB00575,10062237,23,5221,34,3795,0.010001751,0.491740122,0.276079117,0.861090112,0.035572155,DB0057510062237_,3.336192104,-0.709804909,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,clonidine,DB00575
,89921,DB00999,10062237,78,21352,57,12182,0.178411498,0.780749734,0.547332941,1.119505699,0.321852114,DB0099910062237_,1.133663113,-0.247500623,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,hydrochlorothiazide,DB00999
,89922,DB11089,10062237,57,10118,37,8370,0.255596039,1.27437683,0.827114208,1.985009395,0.416380217,DB1108910062237_,0.876156454,0.242457298,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,docusate,DB11089
,89927,DB00169,10006811,65,38626,12,18163,0.001383632,2.547027435,1.363226485,5.182100602,0.007195324,DB0016910006811_,4.934323916,0.934926968,NA,10006811,Bursitis,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,89929,DB00169,10008611,50,38641,15,18160,0.143363345,1.566545671,0.865272025,3.004561326,0.274547779,DB0016910008611_,1.292629976,0.448872986,NA,10008611,Cholecystectomy,10042613,Surgical and medical procedures,Surg,cholecalciferol,DB00169
,89935,DB00555,10010305,130,6917,85,3401,0.047842269,0.75204367,0.565892848,1.00364755,0.121062243,DB0055510010305_,2.111450463,-0.284960885,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,89936,DB00169,10012431,36,38655,15,18160,0.765432056,1.127505109,0.601919916,2.217287545,0.870592021,DB0016910012431_,0.138581815,0.120007323,NA,10012431,Dermatitis,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,89947,DB00169,10024378,61,38630,55,18120,0.000629422,0.520221267,0.355174592,0.763460866,0.003749003,DB0016910024378_,5.586265297,-0.653501044,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,89970,DB00555,10048294,40,7007,40,3446,0.001795568,0.491816165,0.30864886,0.783764315,0.008902483,DB0055510048294_,4.721425066,-0.70965028,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,89979,DB00169,10062244,129,38562,32,18143,0.000898841,1.896639967,1.278929401,2.888879971,0.005045972,DB0016910062244_,5.289165041,0.640083882,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,89984,DB00169,10070488,52,38639,17,18158,0.244490349,1.437469927,0.817628734,2.652361971,0.403138374,DB0016910070488_,0.908475416,0.362884573,NA,10070488,Upper-airway cough syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,89986,DB01050,10029216,57,18051,17,9354,0.04888329,1.737456777,0.995671403,3.188088967,0.122891996,DB0105010029216_,2.096449389,0.552422422,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,89987,DB00295,10007882,77,14586,50,9552,1,1.00850661,0.696719645,1.471387861,1,DB0029510007882_,0,0.008470633,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,morphine,DB00295
,89989,DB00341,10007882,62,11343,31,5037,0.575105903,0.888137979,0.567416341,1.416309933,0.724646567,DB0034110007882_,0.322071237,-0.118628166,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,cetirizine,DB00341
,89991,DB00476,10007882,85,17172,44,6133,0.056243186,0.689963151,0.473376976,1.018036771,0.136536794,DB0047610007882_,1.991161151,-0.371117087,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,duloxetine,DB00476
,89994,DB01015,10007882,60,9827,83,9298,0.028717437,0.683995138,0.481703163,0.966274551,0.081865175,DB0101510007882_,2.502681597,-0.379804469,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,89997,DB11089,10007882,79,10096,73,8334,0.513190726,0.893329027,0.640642121,1.247058174,0.673232262,DB1108910007882_,0.395664894,-0.112800315,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,docusate,DB11089
,90010,DB01050,10022061,156,17952,27,9344,4.18303849514085e-09,3.00722704,1.98785589,4.712317896,1.02232605155534e-07,DB0105010022061_,16.09601518,1.101018405,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,90011,DB01050,10028245,73,18035,23,9348,0.039963406,1.645092374,1.016683481,2.757055119,0.105603512,DB0105010028245_,2.248063654,0.497796537,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,90019,DB00588,10027599,185,16339,33,8435,5.52293060830317e-10,2.89402153,1.987875476,4.332811962,1.61121233117923e-08,DB0058810027599_,17.94369385,1.062647068,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,90025,DB00588,10037400,82,16442,47,8421,0.575898665,0.893570724,0.61623629,1.308927225,0.725328417,DB0058810037400_,0.321130738,-0.112529793,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,90026,DB00588,10043554,54,16470,34,8434,0.367137978,0.813330188,0.519521837,1.28949182,0.536749638,DB0058810043554_,0.622223516,-0.206618116,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,fluticasone propionate,DB00588
,90032,DB00588,10048908,60,16464,28,8440,0.735879571,1.098493062,0.689862138,1.788549812,0.847406972,DB0058810048908_,0.165574213,0.093939297,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,fluticasone propionate,DB00588
,90042,DB00788,10043607,48,9308,36,5025,0.137566776,0.719856306,0.456901407,1.14324376,0.266289322,DB0078810043607_,1.323171886,-0.328703662,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,naproxen,DB00788
,90050,DB01104,10061284,37,15426,25,7261,0.173325517,0.696631678,0.407933703,1.20830173,0.315306334,DB0110410061284_,1.154210623,-0.361498447,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,90077,DB01195,10011906,50,1189,28,716,0.812182901,1.075304621,0.657177083,1.791248095,0.89905753,DB0119510011906_,0.106408254,0.07260399,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,flecainide,DB01195
,90080,DB00316,10019860,96,65378,12,36941,7.73300683164738e-09,4.519962051,2.471588681,9.054547004,1.78065777108937e-07,DB0031610019860_,15.54111282,1.508503598,female,10019860,Hereditary angioedema,10010331,"Congenital, familial and genetic disorders",Cong,acetaminophen,DB00316
,90101,DB00338,10043607,257,33417,236,22036,0.000304304,0.71812184,0.598935969,0.86130506,0.002040985,DB0033810043607_,6.1943229,-0.33111603,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,omeprazole,DB00338
,90102,DB00455,10043607,60,9341,46,5072,0.083082391,0.708284981,0.47358462,1.065350027,0.183591479,DB0045510043607_,1.695042215,-0.344908751,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,loratadine,DB00455
,90103,DB00668,10043607,68,10023,13,4290,0.005003533,2.23874675,1.224139037,4.422852464,0.02048015,DB0066810043607_,3.888299152,0.805916223,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,epinephrine,DB00668
,90104,DB00814,10043607,32,8255,18,3397,0.2793061,0.731586319,0.397849233,1.386336956,0.443143649,DB0081410043607_,0.813861298,-0.312540062,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,meloxicam,DB00814
,90105,DB01175,10043607,62,10662,23,4869,0.481699805,1.230980902,0.750850046,2.084552839,0.646274117,DB0117510043607_,0.436531535,0.207811333,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,escitalopram,DB01175
,90109,DB00924,10053762,260,9902,77,4174,0.006467485,1.423360213,1.096672932,1.86502229,0.025136781,DB0092410053762_,3.683423141,0.353020423,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,90110,DB01195,10053762,31,1208,20,724,0.883662624,0.929009153,0.508579217,1.733656633,0.951363824,DB0119510053762_,0.04985872,-0.073636688,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,flecainide,DB01195
,90117,DB00482,10000081,88,8171,40,3031,0.317000646,0.816069895,0.554100488,1.220440485,0.484820178,DB0048210000081_,0.723977224,-0.203255272,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,celecoxib,DB00482
,90118,DB00575,10000081,74,5170,51,3778,0.784909576,1.060314272,0.730289285,1.549838843,0.883247992,DB0057510000081_,0.124149266,0.058565347,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,clonidine,DB00575
,90132,DB00182,10003239,82,5112,37,2815,0.33581993,1.220322239,0.815727132,1.856445504,0.504969369,DB0018210003239_,0.683257507,0.199114954,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,amphetamine,DB00182
,90133,DB00327,10003239,100,6038,54,4208,0.137983999,1.290560141,0.915536463,1.836350415,0.266900392,DB0032710003239_,1.320879756,0.255076342,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydromorphone,DB00327
,90134,DB00482,10003239,351,7908,98,2973,0.010791934,1.346435253,1.06883406,1.708998356,0.03783979,DB0048210003239_,3.274394092,0.297460547,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,90135,DB01017,10003239,37,1432,14,887,0.144269693,1.636702453,0.858418463,3.296531137,0.275951745,DB0101710003239_,1.287529266,0.492683518,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,minocycline,DB01017
,90137,DB00295,10005364,26,14637,42,9560,0.000260969,0.404337477,0.237829804,0.67554476,0.001800178,DB0029510005364_,6.319869623,-0.905505409,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,morphine,DB00295
,90157,DB00182,10010774,61,5133,24,2828,0.172858855,1.400262575,0.858011919,2.354011695,0.314614719,DB0018210010774_,1.156406503,0.336659773,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,amphetamine,DB00182
,90158,DB00482,10010774,87,8172,39,3032,0.364124686,0.827710717,0.559713163,1.243546745,0.533707986,DB0048210010774_,0.627906433,-0.189091562,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,celecoxib,DB00482
,90173,DB01017,10016256,73,1396,54,847,0.301676624,0.820292395,0.56283553,1.201643367,0.468000711,DB0101710016256_,0.759285463,-0.198094423,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,minocycline,DB01017
,90201,DB00451,10025256,63,47208,16,15403,0.433520629,1.284710259,0.732974908,2.383801895,0.602038818,DB0045110025256_,0.507433354,0.250533213,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,90275,DB00295,10029366,39,14624,26,9576,1,0.982215611,0.582518626,1.681602263,1,DB0029510029366_,0,-0.017944432,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,morphine,DB00295
,90375,DB00246,10047700,45,1029,8,693,0.000153692,3.785967162,1.752221017,9.356524193,0.001151431,DB0024610047700_,6.766749421,1.331301379,female,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ziprasidone,DB00246
,90378,DB01069,10021789,62,6638,16,2379,0.30121007,1.388686853,0.789761683,2.583563182,0.467483863,DB0106910021789_,0.76039045,0.32835859,NA,10021789,Infection,10021881,Infections and infestations,Infec,promethazine,DB01069
,90403,DB00999,10000891,35,21395,36,12203,0.01346606,0.554561226,0.337926721,0.909139475,0.045108002,DB0099910000891_,3.098695625,-0.589578063,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,hydrochlorothiazide,DB00999
,90409,DB00332,10037377,31,2653,21,1635,0.774668659,0.909773273,0.504376206,1.671831184,0.877188029,DB0033210037377_,0.13103391,-0.094559861,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipratropium,DB00332
,90420,DB00343,10008479,227,8509,81,5014,9.69285998085223e-05,1.651321713,1.272610865,2.160709443,0.00077534,DB0034310008479_,7.16220852,0.501576005,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,90421,DB00490,10008479,51,4019,21,1555,0.792510626,0.939650235,0.553077247,1.650422386,0.887531177,DB0049010008479_,0.119311629,-0.062247564,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,90422,DB00490,10013968,153,3917,62,1514,0.756819105,0.953837951,0.701117081,1.310841963,0.863898474,DB0049010013968_,0.146300024,-0.047261485,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,buspirone,DB00490
,90435,DB00158,10069327,39,16776,17,8087,0.777175465,1.105889258,0.610681833,2.086169695,0.878512755,DB0015810069327_,0.129524852,0.100649769,NA,10069327,Product quality issue,10077536,Product issues,Prod,folic acid,DB00158
,90464,DB00285,10014625,76,10875,14,3704,0.037862325,1.848991047,1.035624122,3.54578414,0.101371144,DB0028510014625_,2.288966801,0.614640111,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,90474,DB00472,10039020,22,10737,90,4222,5.59846868899837e-30,0.096138376,0.057337317,0.154852295,1.23660293689346e-27,DB0047210039020_,61.95742946,-2.341966704,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,fluoxetine,DB00472
,90493,DB00331,10019708,48,24898,30,20722,0.255075108,1.331630964,0.826381018,2.177514059,0.415741791,DB0033110019708_,0.877690905,0.286404479,NA,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,metformin,DB00331
,90506,DB00331,10060800,116,24830,52,20700,0.00017659,1.859675796,1.329042834,2.633004834,0.001298002,DB0033110060800_,6.646928844,0.620402169,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,metformin,DB00331
,90526,DB00268,10003239,88,2887,19,1526,0.000181283,2.447733218,1.471661179,4.274259844,0.001327856,DB0026810003239_,6.62418946,0.895162379,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ropinirole,DB00268
,90527,DB00413,10003239,64,2135,33,1174,0.829835335,1.066425538,0.685553866,1.686568543,0.910701924,DB0041310003239_,0.093539632,0.064312437,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pramipexole,DB00413
,90528,DB00257,10013709,42,910,19,603,0.184073779,1.464436574,0.823891375,2.693276663,0.329027683,DB0025710013709_,1.111613389,0.381470577,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,clotrimazole,DB00257
,90529,DB00927,10013709,224,7273,129,4887,0.186062145,1.166729761,0.932341292,1.465045211,0.331557811,DB0092710013709_,1.103953092,0.154204759,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,90532,DB00390,10033371,126,4019,44,3257,6.58574631224175e-07,2.320393694,1.628638413,3.360415639,9.88896554226075e-06,DB0039010033371_,11.52409101,0.841736867,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,90533,DB00572,10016173,94,2808,48,2078,0.038807536,1.449117234,1.007890293,2.106980784,0.103265447,DB0057210016173_,2.270452453,0.370954567,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,atropine,DB00572
,90536,DB00316,10048049,79,65395,12,36941,1.60368540607212e-06,3.718817999,2.013927546,7.501939942,2.18578537197851e-05,DB0031610048049_,10.73095026,1.313405876,female,10048049,Wrist fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,90546,DB00316,10061394,131,65343,44,36909,0.002648108,1.681703981,1.18655093,2.424104611,0.012208283,DB0031610061394_,4.405640638,0.519807554,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,90548,DB00695,10061394,59,27990,24,20504,0.014210365,1.800816723,1.102753121,3.028436596,0.047143689,DB0069510061394_,3.054555131,0.588240297,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,90555,DB00108,10013887,46,10148,14,3281,1,1.062300584,0.572954456,2.095129817,1,DB0010810013887_,0,0.060436918,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,90557,DB00108,10047513,74,10120,24,3271,1,0.996599371,0.620289904,1.654824182,1,DB0010810047513_,0,-0.003406424,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,natalizumab,DB00108
,90560,DB06637,10008531,43,6119,17,2002,0.547492737,0.827565363,0.461060809,1.551438928,0.702146647,DB0663710008531_,0.353612998,-0.189267186,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,90562,DB09072,10011906,34,6437,23,2512,0.053381778,0.576931063,0.329303665,1.027926974,0.131349406,DB0907210011906_,2.029894282,-0.550032495,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,90602,DB00227,10020772,33,2434,27,1776,0.693943533,0.891835937,0.517914283,1.547979227,0.815769362,DB0022710020772_,0.203623609,-0.11447309,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,lovastatin,DB00227
,90603,DB00727,10020772,81,3762,60,4113,0.026721437,1.475874034,1.040688443,2.103010285,0.077396472,DB0072710020772_,2.558814085,0.38925038,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,nitroglycerin,DB00727
,90627,DB00331,10040984,85,24861,44,20708,0.01011638,1.609089975,1.104882737,2.372591067,0.035899515,DB0033110040984_,3.327031486,0.475668787,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,metformin,DB00331
,90633,DB01261,10044565,35,3746,22,3281,0.233195745,1.393358404,0.792928487,2.498684675,0.389771726,DB0126110044565_,0.94219403,0.331716951,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,sitagliptin,DB01261
,90654,DB01261,10056342,24,3757,37,3266,0.028758236,0.563928931,0.321986014,0.970422557,0.081950371,DB0126110056342_,2.501641446,-0.572827044,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sitagliptin,DB01261
,90673,DB00364,10000081,94,2656,32,1368,0.044769411,1.512848746,0.997260151,2.348658417,0.11513198,DB0036410000081_,2.161676154,0.41399446,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,sucralfate,DB00364
,90675,DB06186,10000081,46,2163,77,3569,1,0.985730102,0.666063934,1.444759902,1,DB0618610000081_,0,-0.014372692,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ipilimumab,DB06186
,90677,DB09020,10000081,43,1911,31,1573,0.637379561,1.141707406,0.699171565,1.883929523,0.774693506,DB0902010000081_,0.255287803,0.132524867,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,bisacodyl,DB09020
,90683,DB08881,10013950,19,604,34,777,0.32297535,0.719046163,0.383370519,1.311776254,0.491398881,DB0888110013950_,0.710499096,-0.329829718,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,vemurafenib,DB08881
,90705,DB00335,10042682,54,8412,15,5450,0.002767499,2.332247553,1.295583307,4.454609609,0.012652179,DB0033510042682_,4.36992584,0.846832418,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,90719,DB00316,10000269,42,65432,32,36921,0.225735061,0.740622341,0.456409411,1.212309074,0.380556462,DB0031610000269_,0.966120723,-0.300264446,NA,10000269,Abscess,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,90773,DB00480,10049438,86,67342,82,67580,0.757928937,1.052505794,0.768469091,1.442379212,0.86479195,DB0048010049438_,0.145266321,0.051173791,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,90774,DB00904,10049438,70,22999,30,14426,0.081144644,1.463556172,0.941044023,2.327095796,0.180325241,DB0090410049438_,1.712993162,0.380869208,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,90777,DB00285,10010264,243,10708,66,3652,0.112545373,1.25566659,0.950279351,1.67882484,0.229892378,DB0028510010264_,1.470144,0.227666579,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,90794,DB01202,10013395,19,6695,32,5686,0.016915816,0.50429945,0.269759743,0.918341041,0.054197004,DB0120210013395_,2.915129648,-0.68458504,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,90796,DB00555,10020937,71,6976,23,3463,0.078491312,1.53235804,0.943900617,2.575093335,0.175841925,DB0055510020937_,1.738169843,0.426807752,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,90797,DB01104,10020937,181,15282,58,7228,0.009792891,1.475983882,1.090895426,2.022595456,0.034997435,DB0110410020937_,3.35248052,0.389324806,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,90798,DB01202,10020937,67,6647,28,5690,0.001251666,2.048189512,1.297507663,3.312118628,0.006619729,DB0120210020937_,5.017700901,0.716956238,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,90799,DB01202,10042458,42,6672,36,5682,1,0.9935552,0.620408766,1.598494263,1,DB0120210042458_,0,-0.006465657,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,90811,DB00451,10057371,44,47227,8,15411,0.14697315,1.794653978,0.835501645,4.414911048,0.279749483,DB0045110057371_,1.273860779,0.584812233,NA,10057371,Hypoaesthesia oral,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,90816,DB00451,10057372,51,47220,8,15411,0.049439255,2.08044136,0.979828195,5.077380589,0.123963638,DB0045110057372_,2.087766998,0.732580064,NA,10057372,Paraesthesia oral,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,90821,DB00555,10074903,46,7001,19,3467,0.597285237,1.198900533,0.687527822,2.170334259,0.742475406,DB0055510074903_,0.297765533,0.181404914,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,lamotrigine,DB00555
,90828,DB09072,10013911,44,6427,13,2522,0.460128036,1.328077013,0.701113448,2.692499051,0.627566776,DB0907210013911_,0.465905198,0.283732041,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,90829,DB01050,10013952,67,18041,27,9344,0.326539619,1.285267085,0.81026608,2.091904815,0.495016661,DB0105010013952_,0.703163858,0.250966545,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,90832,DB06413,10016322,63,1493,26,648,0.9064704,1.051653103,0.649413321,1.747325303,0.958224861,DB0641310016322_,0.042672809,0.05036331,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,armodafinil,DB06413
,90851,DB00196,10002855,106,4977,20,3265,1.13171006155799e-08,3.476451439,2.136728058,5.932696743,2.51879754174866e-07,DB0019610002855_,15.19431403,1.246012072,female,10002855,Anxiety,10037175,Psychiatric disorders,Psych,fluconazole,DB00196
,90857,DB00254,10024855,41,5894,15,3373,0.163319122,1.564153099,0.846137237,3.04697386,0.301834472,DB0025410024855_,1.197876519,0.447344527,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,doxycycline,DB00254
,90864,DB00196,10033371,205,4878,57,3228,1.05977807961336e-09,2.379730852,1.760128169,3.26162533,2.93223861290916e-08,DB0019610033371_,17.34491458,0.866987394,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,90865,DB01212,10033371,55,1964,16,1925,5.81147595797014e-06,3.368642664,1.894092942,6.320894025,6.73669881169769e-05,DB0121210033371_,9.605355451,1.214509893,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ceftriaxone,DB01212
,90881,DB00316,10033553,88,65386,51,36902,0.929609499,0.973800589,0.681866004,1.403545665,0.971029456,DB0031610033553_,0.029398475,-0.026548731,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,90894,DB00316,10039674,93,65381,36,36917,0.054303208,1.458658727,0.982725967,2.20744013,0.133043745,DB0031610039674_,2.017077298,0.377517333,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,90895,DB00381,10039674,49,29311,13,22874,0.000265665,2.941334552,1.570945907,5.911588669,0.001827294,DB0038110039674_,6.304919032,1.078863408,female,10039674,Sciatica,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,90898,DB00999,10039674,46,21384,11,12228,0.008205943,2.391229425,1.219529519,5.122121863,0.030411449,DB0099910039674_,3.492936138,0.871807637,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,90903,DB01069,10061818,82,6618,41,2354,0.080009605,0.711421956,0.481710106,1.065111813,0.17842892,DB0106910061818_,1.723564967,-0.340489557,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,90905,DB00108,10028596,72,10122,35,3260,0.054136973,0.662568063,0.435603599,1.024728539,0.132710686,DB0010810028596_,2.019583815,-0.411631989,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,natalizumab,DB00108
,90910,DB00588,10029216,54,16470,15,8453,0.040632638,1.847609171,1.026877077,3.527472421,0.106915149,DB0058810029216_,2.235719759,0.613892463,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,90921,DB06616,10011906,38,923,37,766,0.553954561,0.852411861,0.521852732,1.393386651,0.707500543,DB0661610011906_,0.346016882,-0.159685464,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,bosutinib,DB06616
,90930,DB08908,10010305,122,10551,42,3237,0.517247937,0.891160606,0.621328094,1.300529651,0.676865657,DB0890810010305_,0.390282464,-0.115230614,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,dimethyl fumarate,DB08908
,90932,DB08908,10073954,47,10626,6,3273,0.034749706,2.412785422,1.028164245,6.911168818,0.094957483,DB0890810073954_,2.354326035,0.880781857,NA,10073954,Intentional underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,dimethyl fumarate,DB08908
,90933,DB00196,10000087,66,5017,18,3267,0.000669132,2.387452958,1.39753991,4.281869472,0.003947955,DB0019610000087_,5.534557509,0.87022709,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,fluconazole,DB00196
,90938,DB00370,10008479,50,4491,26,3637,0.081444349,1.55730377,0.948942706,2.611856661,0.180769661,DB0037010008479_,1.710531647,0.442955974,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,90939,DB00395,10008479,40,2144,13,723,1,1.037611126,0.539971521,2.126765746,1,DB0039510008479_,0,0.036921077,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,carisoprodol,DB00395
,90941,DB00196,10013573,140,4943,46,3239,2.70922075325855e-05,1.994142975,1.415170154,2.855456518,0.000259141,DB0019610013573_,8.258139356,0.690214372,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,fluconazole,DB00196
,90943,DB00395,10013573,65,2119,17,719,0.438543321,1.297239463,0.745494412,2.377011457,0.606918145,DB0039510013573_,0.499361348,0.260238517,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,carisoprodol,DB00395
,90947,DB00196,10020937,67,5016,20,3265,0.001831253,2.180382258,1.303818654,3.801661041,0.009051238,DB0019610020937_,4.704853758,0.779500209,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,fluconazole,DB00196
,90949,DB00404,10020937,252,19640,61,9801,8.7723368981953e-08,2.061532735,1.551314027,2.776533015,1.60851674481384e-06,DB0040410020937_,13.34019808,0.723449752,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,90960,DB00404,10038063,38,19854,22,9840,0.58383808,0.856081432,0.493262274,1.520465382,0.731764977,DB0040410038063_,0.312295886,-0.155389776,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,90974,DB00395,10074903,41,2143,11,725,0.628787859,1.260870599,0.632316602,2.73493228,0.767981646,DB0039510074903_,0.263989444,0.231802434,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,carisoprodol,DB00395
,90975,DB00404,10074903,175,19717,175,9687,6.90219079569765e-11,0.491301185,0.395544104,0.610243778,2.31851865897652e-09,DB0040410074903_,19.88233736,-0.710697928,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,90976,DB00788,10074903,83,9273,23,5038,0.004001709,1.960513668,1.221219505,3.265405018,0.017086568,DB0078810074903_,4.06946261,0.673206514,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,90990,DB00706,10020937,10,1065,113,15812,0.355224459,1.313863972,0.611554406,2.516305905,0.524982425,DB0070610020937_,0.644390494,0.272972392,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,90991,DB01268,10020937,24,2119,31,3099,0.680022795,1.132214758,0.633932413,1.999349975,0.806455783,DB0126810020937_,0.215106209,0.124175677,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,sunitinib,DB01268
,90992,DB01268,10033425,156,1987,171,2959,0.00880999,1.358444664,1.078064901,1.710800801,0.032160347,DB0126810033425_,3.437021036,0.306340416,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sunitinib,DB01268
,90996,DB00706,10047942,17,1058,207,15718,0.406718175,1.220068438,0.694517448,2.011257219,0.57625358,DB0070610047942_,0.551207471,0.198906954,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,tamsulosin,DB00706
,90999,DB00563,10044390,45,46601,7,15341,0.075239123,2.116126691,0.947091713,5.562998,0.170236378,DB0056310044390_,1.770567349,0.749587385,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,91004,DB00465,10002855,67,2037,8,875,0.000154878,3.596052981,1.714362705,8.707834912,0.00115916,DB0046510002855_,6.760059691,1.27983685,female,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ketorolac,DB00465
,91006,DB00734,10012378,55,3995,62,4840,0.709338733,1.074709884,0.731801676,1.574715879,0.826544135,DB0073410012378_,0.190501963,0.07205075,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,91009,DB00316,10013082,164,65310,67,36886,0.027948114,1.382450428,1.034080624,1.865950792,0.080110815,DB0031610013082_,2.524344414,0.323857597,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,91010,DB00404,10013082,43,19849,15,9847,0.266108563,1.422124652,0.774085466,2.757271934,0.42822723,DB0040410013082_,0.848101313,0.352151987,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,91013,DB00904,10013082,51,23018,20,14436,0.086888781,1.599241371,0.936369515,2.833206551,0.189855905,DB0090410013082_,1.66148989,0.469529374,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,91020,DB01212,10053762,83,1936,81,1860,0.936562261,0.984467636,0.711065202,1.363437691,0.976653933,DB0121210053762_,0.023622904,-0.015654255,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ceftriaxone,DB01212
,91041,DB08908,10001949,66,10607,20,3259,1,1.013926323,0.605911609,1.768526104,1,DB0890810001949_,0,0.013830243,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,91044,DB00181,10003246,55,9801,11,5860,0.000308384,2.989307122,1.546022916,6.339247879,0.002063877,DB0018110003246_,6.183169104,1.095041629,female,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,91046,DB01076,10003246,148,25599,86,25497,5.97661319397146e-05,1.714044933,1.304497554,2.263903765,0.000514055,DB0107610003246_,7.57317985,0.538856035,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,91047,DB01104,10003246,67,15396,14,7272,0.003922503,2.260370098,1.257002732,4.358022569,0.016805703,DB0110410003246_,4.086036969,0.81552856,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,91051,DB00181,10019974,45,9811,14,5857,0.031000959,1.918799505,1.033224038,3.788915085,0.086923057,DB0018110019974_,2.442731957,0.651699733,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,baclofen,DB00181
,91055,DB00338,10028245,69,33605,14,22258,8.59274049382128e-06,3.26431804,1.819818569,6.281963045,9.50990247916179e-05,DB0033810028245_,9.260591843,1.183050871,female,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,91056,DB01104,10028245,44,15419,15,7271,0.328696892,1.383259741,0.754499848,2.67785548,0.497311795,DB0110410028245_,0.698538095,0.324442845,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,91061,DB01076,10040808,28,25719,37,25546,0.266136138,0.751673099,0.442948298,1.262442845,0.428258495,DB0107610040808_,0.848028306,-0.285453758,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,atorvastatin,DB01076
,91068,DB00355,10011224,103,1690,55,1208,0.096996317,1.338486503,0.94714769,1.908549426,0.206274126,DB0035510011224_,1.578549286,0.291539501,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,aztreonam,DB00355
,91071,DB06282,10011224,55,1485,14,519,0.329364239,1.372786627,0.745433831,2.696773311,0.498006156,DB0628210011224_,0.697142841,0.316842708,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levocetirizine,DB06282
,91072,DB14500,10011224,205,7604,68,4005,0.000965407,1.587777478,1.197828588,2.126756744,0.005351834,DB1450010011224_,5.230315894,0.462335226,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,91075,DB00381,10011878,57,29303,26,22861,0.026243443,1.71032292,1.057625505,2.834936123,0.076302075,DB0038110011878_,2.573055149,0.536682195,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,amlodipine,DB00381
,91083,DB00355,10016256,37,1756,14,1249,0.04498062,1.879431211,0.987386692,3.7806561,0.115533845,DB0035510016256_,2.158191762,0.630969184,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,aztreonam,DB00355
,91084,DB00564,10016256,121,2483,59,1404,0.382945178,1.159631575,0.836406979,1.622601749,0.553015631,DB0056410016256_,0.592369013,0.148102347,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,carbamazepine,DB00564
,91086,DB06282,10016256,102,1438,37,496,0.840751957,0.950890453,0.63704508,1.445553218,0.918674116,DB0628210016256_,0.084823827,-0.050356414,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,levocetirizine,DB06282
,91087,DB00281,10016322,127,11331,46,5625,0.073837773,1.370557957,0.969386718,1.967672246,0.167920563,DB0028110016322_,1.78426425,0.315217925,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,91089,DB00564,10016322,52,2552,15,1448,0.020456556,1.966686882,1.085686798,3.775833515,0.062896314,DB0056410016322_,2.766267722,0.676350341,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,carbamazepine,DB00564
,91093,DB14500,10016322,160,7649,40,4033,1.11793609441182e-05,2.10891697,1.479798487,3.068633885,0.000119475,DB1450010016322_,9.032400895,0.746174532,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,91094,DB00281,10028810,186,11272,70,5601,0.052161945,1.320333289,0.99587246,1.76720402,0.129085038,DB0028110028810_,2.047283881,0.277884196,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,lidocaine,DB00281
,91098,DB00956,10028810,66,5748,22,3445,0.019504897,1.797910906,1.092840532,3.065997629,0.060635116,DB0095610028810_,2.802881078,0.586625383,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,hydrocodone,DB00956
,91106,DB01076,10029216,90,25657,53,25530,0.002470442,1.689680513,1.18980228,2.420509295,0.011559513,DB0107610029216_,4.460246516,0.524539465,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,91114,DB00563,10030995,39,46607,11,15337,0.744655779,1.166699755,0.58579905,2.526325425,0.854187399,DB0056310030995_,0.157604672,0.154179041,NA,10030995,Oral mucosal blistering,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,91123,DB00355,10035664,75,1718,50,1213,0.781596729,1.059070909,0.724780018,1.558802757,0.881104369,DB0035510035664_,0.126579193,0.057392023,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,aztreonam,DB00355
,91125,DB06282,10035664,45,1495,20,513,0.386418428,0.772175531,0.441840102,1.394165361,0.556578902,DB0628210035664_,0.585946336,-0.258543383,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,levocetirizine,DB06282
,91129,DB01076,10042128,98,25649,71,25512,0.045011469,1.372895487,1.00073403,1.891487217,0.115596137,DB0107610042128_,2.157652741,0.316922004,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,91150,DB08895,10000059,589,27525,97,6549,0.00059017,1.444721516,1.161611095,1.813039481,0.003546957,DB0889510000059_,5.641665142,0.367916581,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,91153,DB00455,10005750,92,9309,41,5077,0.316172606,1.223736582,0.836741611,1.817167038,0.483835295,DB0045510005750_,0.726010729,0.20190895,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,loratadine,DB00455
,91154,DB00455,10008469,115,9286,34,5084,0.001344206,1.851735454,1.251221356,2.805194589,0.007022946,DB0045510008469_,4.958572463,0.616123283,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,91160,DB01075,10016173,350,19598,155,10942,0.016944372,1.26074864,1.038982678,1.535464034,0.054252057,DB0107510016173_,2.914114377,0.231705703,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,91173,DB00381,10007882,163,29197,128,22759,0.952828555,0.992641241,0.782163189,1.262049966,0.990805996,DB0038110007882_,0.00923653,-0.007385969,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,amlodipine,DB00381
,91175,DB06643,10007882,99,52322,23,7492,0.040004311,0.616349917,0.388168439,1.017650517,0.105688616,DB0664310007882_,2.247258091,-0.48394043,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,denosumab,DB06643
,91179,DB08875,10040047,14,629,36,1207,0.449796922,0.746355459,0.36896651,1.430642376,0.617416684,DB0887510040047_,0.482211144,-0.292553305,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,cabozantinib,DB08875
,91182,DB00590,10053762,19,757,43,1909,0.671694675,1.114228681,0.609079342,1.968218926,0.800776157,DB0059010053762_,0.222173826,0.1081624,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,doxazosin,DB00590
,91183,DB06643,10053762,26518,25903,2972,4543,3.92650270982704e-72,1.56486569,1.48919791,1.644640944,4.58702772123572e-69,DB0664310053762_,157.3551392,0.4478,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,91184,DB08899,10053762,30,219,65,8068,2.3120741045468e-23,16.98400636,10.41385081,27.16027857,3.19857199147435e-21,DB0889910053762_,47.1915825,2.832272099,female,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,enzalutamide,DB08899
,91195,DB00381,10062355,234,29126,113,22774,2.1326149140397e-05,1.619165327,1.287200583,2.046600873,0.000210934,DB0038110062355_,8.463963976,0.481910786,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,91197,DB06643,10062355,194,52227,25,7490,0.683119207,1.112900536,0.731018081,1.763588279,0.808418727,DB0664310062355_,0.212675128,0.106969703,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,91201,DB08911,10028813,116,1523,73,1675,0.00030347,1.747327309,1.281401371,2.395448153,0.002035912,DB0891110028813_,6.196811581,0.558087368,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,trametinib,DB08911
,91205,DB08911,10047700,74,1565,45,1703,0.002672703,1.78912852,1.210430217,2.66990507,0.012303326,DB0891110047700_,4.397885683,0.581728641,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,trametinib,DB08911
,91217,DB00788,10007515,60,9296,46,5015,0.08220694,0.703717108,0.470505936,1.058488949,0.182014427,DB0078810007515_,1.703669324,-0.351378839,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,naproxen,DB00788
,91220,DB00788,10042772,48,9308,40,5021,0.044085464,0.647309141,0.415983313,1.012210949,0.113754505,DB0078810042772_,2.173712616,-0.434931292,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,91229,DB00448,10010305,31,5114,24,3100,0.403172294,0.783017879,0.443898001,1.396973147,0.572931978,DB0044810010305_,0.556988282,-0.24459975,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,lansoprazole,DB00448
,91232,DB00646,10028372,35,3418,26,1974,0.350934735,0.777497739,0.453288488,1.349343088,0.520647938,DB0064610028372_,0.652681209,-0.251674542,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,nystatin,DB00646
,91238,DB00169,10022611,53,38638,22,18153,0.710568567,1.131836911,0.676447058,1.954917602,0.827399154,DB0016910022611_,0.189468048,0.123841898,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,91252,DB00343,10005734,51,8685,25,5070,0.5513887,1.190903866,0.723331531,2.008466556,0.705422208,DB0034310005734_,0.348958779,0.17471257,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,diltiazem,DB00343
,91254,DB08931,10005734,224,6353,67,2379,0.122962172,1.251908016,0.944751677,1.677362354,0.245671989,DB0893110005734_,1.403758009,0.224668801,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,riociguat,DB08931
,91255,DB13961,10005734,33,9424,24,6390,0.788557272,0.932331675,0.533980771,1.650267449,0.885530673,DB1396110005734_,0.121568183,-0.070066653,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,fish oil,DB13961
,91259,DB00374,10013578,78,17638,24,5700,0.908318065,1.050255046,0.656653437,1.737707214,0.958996855,DB0037410013578_,0.041867483,0.049033036,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,91260,DB00451,10013578,37,47234,18,15401,0.160827832,0.670234313,0.371923111,1.250955794,0.298629795,DB0045110013578_,1.208550616,-0.400127907,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,91262,DB06403,10013578,50,21421,14,6647,0.882964835,1.108220246,0.602700545,2.172081864,0.951066996,DB0640310013578_,0.050170771,0.102755346,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,91270,DB13961,10037400,31,9426,21,6393,1,1.001197225,0.556649676,1.834969914,1,DB1396110037400_,0,0.001196509,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,91274,DB00374,10040829,42,17674,12,5712,0.873968268,1.13114593,0.584115598,2.36195929,0.945282526,DB0037410040829_,0.056271427,0.123231216,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,treprostinil,DB00374
,91275,DB00451,10040829,165,47106,44,15375,0.2600655,1.223958642,0.872519544,1.749063953,0.421353078,DB0045110040829_,0.864284131,0.202090394,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,91276,DB00788,10040829,38,9318,12,5049,0.104625874,1.715813392,0.876777192,3.610038671,0.217941205,DB0078810040829_,1.523529955,0.539887249,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,naproxen,DB00788
,91279,DB13961,10040829,56,9401,20,6394,0.013412806,1.904315231,1.123755722,3.353813514,0.044980302,DB1396110040829_,3.101530617,0.644122485,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,fish oil,DB13961
,91290,DB00425,10024264,76,12619,59,7425,0.128226387,0.757964894,0.531665068,1.085107944,0.253139854,DB0042510024264_,1.37381316,-0.277118209,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,91292,DB00215,10060795,43,11060,9,5267,0.024688799,2.27518,1.092907475,5.311573632,0.072821084,DB0021510060795_,2.61974975,0.82205917,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,citalopram,DB00215
,91294,DB00425,10060795,42,12653,18,7466,0.285868266,1.376780284,0.774874426,2.543054577,0.450536477,DB0042510060795_,0.797316236,0.319747646,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,zolpidem,DB00425
,91323,DB00706,10047571,8,1067,66,15859,0.142095994,1.80151336,0.74481293,3.774152237,0.272726776,DB0070610047571_,1.299284804,0.588627067,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,tamsulosin,DB00706
,91324,DB00736,10047571,67,10524,21,5532,0.042252397,1.677042408,1.012935457,2.886531754,0.110200858,DB0073610047571_,2.205450594,0.51703177,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,esomeprazole,DB00736
,91325,DB00999,10047571,154,21276,52,12187,0.000794354,1.696358566,1.230251109,2.371876581,0.004548434,DB0099910047571_,5.392972207,0.528483934,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,hydrochlorothiazide,DB00999
,91326,DB06228,10047571,55,15857,37,16039,0.06000147,1.503520399,0.972753219,2.347756799,0.143469811,DB0622810047571_,1.941630645,0.407809291,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,rivaroxaban,DB06228
,91355,DB01268,10002034,43,2100,68,3062,0.697449703,0.922030364,0.611676771,1.376706776,0.818066688,DB0126810002034_,0.20081142,-0.081177123,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,sunitinib,DB01268
,91357,DB01268,10017885,44,2099,55,3075,0.470040077,1.171945867,0.766903168,1.78186337,0.636298266,DB0126810017885_,0.452087854,0.158665502,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,91361,DB00213,10055798,79,18816,68,13353,0.275438399,0.824470074,0.588109908,1.158435783,0.438766325,DB0021310055798_,0.823788298,-0.193014434,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,pantoprazole,DB00213
,91365,DB01268,10055798,22,2121,37,3093,0.689693714,0.86713218,0.485780052,1.513952888,0.812888491,DB0126810055798_,0.207161336,-0.142563857,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,sunitinib,DB01268
,91376,DB00958,10006002,63,4531,16,2569,0.003015511,2.232276151,1.270735881,4.150303821,0.013567737,DB0095810006002_,4.300060582,0.80302176,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,carboplatin,DB00958
,91377,DB01373,10006002,227,22493,36,7345,1.90263383721058e-05,2.059140865,1.442285688,3.017285389,0.000191173,DB0137310006002_,8.562334308,0.72228884,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,91384,DB01373,10019974,144,22576,37,7344,0.225058354,1.266018694,0.87593377,1.871491828,0.379902952,DB0137310019974_,0.967839447,0.23587709,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,calcium,DB01373
,91399,DB01373,10060820,67,22653,13,7368,0.091147417,1.676228238,0.916275963,3.312042538,0.197088669,DB0137310060820_,1.624101556,0.516546173,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,91419,DB13961,10001551,40,9417,28,6386,0.901997087,0.968749553,0.582279633,1.632354075,0.957184982,DB1396110001551_,0.043758612,-0.031749159,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,fish oil,DB13961
,91424,DB13961,10003481,39,9418,25,6389,0.898734342,1.058279807,0.623776792,1.826404802,0.95647837,DB1396110003481_,0.044497104,0.056644766,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,fish oil,DB13961
,91451,DB08907,10023379,84,4169,39,3871,0.000350903,1.999718831,1.348619911,3.011596838,0.002298403,DB0890710023379_,6.075540682,0.693006586,NA,10023379,Ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,canagliflozin,DB08907
,91453,DB08907,10053762,136,4117,78,3832,0.000662932,1.622787636,1.215019145,2.180005589,0.003920174,DB0890710053762_,5.541619191,0.484145433,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,canagliflozin,DB08907
,91456,DB08910,10003983,38,16706,47,17441,0.449213651,0.844086998,0.535240634,1.323340155,0.616834119,DB0891010003983_,0.483155142,-0.169499711,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,pomalidomide,DB08910
,91464,DB00295,10009033,56,14607,50,9552,0.112084309,0.732428929,0.490738712,1.095762642,0.229191027,DB0029510009033_,1.473199444,-0.311388968,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,91465,DB00433,10009033,32,7624,30,5990,0.522578215,0.838068975,0.492551545,1.429467581,0.681079914,DB0043310009033_,0.384075631,-0.176654872,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,91469,DB00904,10009033,105,22964,62,14394,0.750245709,1.0615335,0.767700905,1.478505656,0.858651012,DB0090410009033_,0.152392713,0.059714561,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,91476,DB00012,10013573,55,1591,38,1275,0.525545438,1.159837149,0.747922721,1.815134134,0.683569636,DB0001210013573_,0.380426747,0.148279606,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,darbepoetin alfa,DB00012
,91477,DB00295,10013573,230,14433,131,9471,0.212399313,1.152148007,0.924094605,1.441228956,0.364289318,DB0029510013573_,1.009806898,0.141628033,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,morphine,DB00295
,91478,DB00484,10013573,85,2422,48,1732,0.211340774,1.266274254,0.873523097,1.853877583,0.362971169,DB0048410013573_,1.013431873,0.23607893,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,brimonidine,DB00484
,91549,DB01069,10016173,188,6512,55,2340,0.209286069,1.228240108,0.901370241,1.696919588,0.360349952,DB0106910016173_,1.020679631,0.205582338,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,promethazine,DB01069
,91553,DB00285,10018884,48,10903,25,3693,0.104195449,0.650352349,0.392481273,1.102370617,0.217337928,DB0028510018884_,1.526301863,-0.430240988,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,venlafaxine,DB00285
,91557,DB00654,10018884,22,3794,31,2567,0.010725186,0.480213485,0.264274986,0.858729343,0.037641616,DB0065410018884_,3.27964504,-0.733524515,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,latanoprost,DB00654
,91558,DB00836,10018884,63,5472,59,4016,0.196911015,0.783702121,0.539313216,1.140158531,0.345260892,DB0083610018884_,1.06345494,-0.243726278,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,loperamide,DB00836
,91561,DB01069,10018884,74,6626,28,2367,0.821192144,0.944107327,0.601933965,1.519160662,0.904725148,DB0106910018884_,0.100124085,-0.057515425,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,promethazine,DB01069
,91570,DB00654,10022437,50,3766,41,2557,0.390589057,0.828042009,0.535157023,1.287614584,0.560453534,DB0065410022437_,0.579008941,-0.188691391,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,latanoprost,DB00654
,91571,DB00697,10022437,159,5937,37,1769,0.196553186,1.280384337,0.886630802,1.891763771,0.344805987,DB0069710022437_,1.064773378,0.247160296,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,tizanidine,DB00697
,91572,DB00813,10022437,115,10457,80,10088,0.025677878,1.38674781,1.032030072,1.871019874,0.074990404,DB0081310022437_,2.590395117,0.326961301,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,fentanyl,DB00813
,91576,DB08910,10022437,109,16635,82,17406,0.024485446,1.390856923,1.033929846,1.877108395,0.072363682,DB0891010022437_,2.62605074,0.329920049,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,pomalidomide,DB08910
,91577,DB09153,10022437,59,7740,45,5654,0.842476263,0.957731759,0.637780848,1.446857118,0.919801687,DB0915310022437_,0.08359719,-0.043187542,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,sodium chloride,DB09153
,91580,DB00433,10024855,42,7614,36,5984,0.732252677,0.916913817,0.572627866,1.474991785,0.844418874,DB0043310024855_,0.169106611,-0.086741795,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,91581,DB00455,10024855,55,9346,41,5077,0.133746778,0.728762221,0.476767366,1.121720251,0.260970533,DB0045510024855_,1.343347779,-0.316407771,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,91586,DB00697,10024855,87,6009,19,1787,0.245662676,1.36165761,0.819194147,2.376352569,0.404538495,DB0069710024855_,0.905008381,0.308702788,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,91587,DB00736,10024855,82,10509,24,5529,0.01015085,1.797518868,1.127295925,2.966659631,0.035992864,DB0073610024855_,3.32443458,0.586407308,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,91591,DB01222,10024855,58,9216,29,5376,0.577489422,1.166685297,0.733789347,1.892591318,0.726502713,DB0122210024855_,0.319513061,0.154166648,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,91595,DB00175,10027175,105,8026,45,6061,0.001192695,1.76198937,1.229256086,2.561539017,0.006376482,DB0017510027175_,5.055138704,0.566443495,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,91596,DB00455,10027175,96,9305,24,5094,0.00034516,2.189685749,1.386103687,3.587372999,0.002268702,DB0045510027175_,6.088547622,0.78375804,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,91598,DB00480,10027175,494,66934,353,67309,9.35668377181806e-07,1.407263931,1.224560389,1.618628424,1.3520254677039e-05,DB0048010027175_,11.21132165,0.341647345,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,91602,DB00682,10027175,188,19271,95,16269,4.26928209774223e-05,1.670642772,1.297341066,2.163258302,0.000385894,DB0068210027175_,7.859946904,0.513208446,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,91603,DB00904,10027175,236,22833,69,14387,3.60085189768252e-09,2.155067187,1.640115435,2.863115519,8.91227797839783e-08,DB0090410027175_,16.23325087,0.7678219,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,91607,DB01222,10027175,64,9210,32,5373,0.52494371,1.166794,0.75082394,1.846107299,0.683060946,DB0122210027175_,0.38117119,0.154259817,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,91608,DB08910,10027175,122,16622,77,17411,0.000472377,1.659586539,1.236558404,2.239031842,0.002945423,DB0891010027175_,5.827502702,0.506568499,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,91612,DB13961,10027175,127,9330,74,6340,0.31177515,1.166173988,0.867122259,1.578018846,0.479184295,DB1396110027175_,0.735670007,0.153728295,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,91614,DB00285,10043607,43,10908,20,3698,0.246624399,0.728904111,0.41896017,1.309759585,0.40570999,DB0028510043607_,0.902116686,-0.31621309,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,venlafaxine,DB00285
,91615,DB00433,10043607,84,7572,70,5950,0.744330123,0.942973501,0.677141485,1.316518491,0.853962912,DB0043310043607_,0.157867515,-0.058717098,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,prochlorperazine,DB00433
,91623,DB01069,10043607,46,6654,26,2369,0.079462027,0.629928391,0.380300393,1.064115167,0.177535272,DB0106910043607_,1.728585974,-0.462149131,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,promethazine,DB01069
,91627,DB13961,10043607,71,9386,63,6351,0.132672806,0.762593149,0.53465078,1.089865991,0.259549323,DB1396110043607_,1.348808526,-0.271030615,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,fish oil,DB13961
,91631,DB00381,10050819,42,29318,36,22851,0.732225643,0.909324258,0.568478568,1.461288084,0.844418874,DB0038110050819_,0.169106611,-0.095053529,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,91639,DB00682,10050819,34,19425,18,16346,0.125588451,1.589462548,0.872454161,2.990638174,0.249468539,DB0068210050819_,1.38842247,0.463395939,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,91641,DB00722,10050819,37,25366,47,25985,0.382431325,0.80644949,0.509463228,1.268057265,0.552516414,DB0072210050819_,0.593272137,-0.215114012,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,91644,DB00904,10050819,51,23018,35,14421,0.739488074,0.912917628,0.581931731,1.447139595,0.85016024,DB0090410050819_,0.16233043,-0.091109623,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,91655,DB00295,10055798,33,14630,28,9574,0.358893123,0.771286825,0.451620943,1.325746858,0.528648417,DB0029510055798_,0.637431687,-0.259694957,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,morphine,DB00295
,91656,DB00425,10055798,32,12663,29,7455,0.110392107,0.649666854,0.380290821,1.114014534,0.22664765,DB0042510055798_,1.484358672,-0.43129558,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,zolpidem,DB00425
,91664,DB00722,10055798,91,25312,105,25927,0.431391083,0.887726334,0.662610873,1.187440217,0.599810343,DB0072210055798_,0.51114177,-0.119091766,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,lisinopril,DB00722
,91674,DB00381,10061225,53,29307,38,22849,0.751484036,1.087419808,0.703212861,1.695984645,0.859679345,DB0038110061225_,0.151195814,0.083807741,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,91675,DB00425,10061225,39,12656,17,7467,0.333965292,1.353502589,0.747322365,2.553586272,0.503024337,DB0042510061225_,0.687116726,0.302695743,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,91684,DB00722,10061225,50,25353,40,25992,0.247747983,1.281495324,0.828358945,1.993917017,0.407054365,DB0072210061225_,0.898808527,0.248027618,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,91705,DB01225,10037377,162,4882,153,4487,0.818849611,0.973150666,0.772381974,1.226617116,0.903336849,DB0122510037377_,0.101659762,-0.027216362,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enoxaparin,DB01225
,91708,DB00788,10051055,53,9303,36,5025,0.316163845,0.795247664,0.510334554,1.251998628,0.483835295,DB0078810051055_,0.726010729,-0.229101686,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,naproxen,DB00788
,91711,DB00788,10060795,34,9322,19,5042,0.886458155,0.967849021,0.536022352,1.798155297,0.952754032,DB0078810060795_,0.048398507,-0.032679174,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,naproxen,DB00788
,91720,DB08827,10019211,52,1110,17,565,0.151138783,1.556602703,0.875987939,2.899145565,0.285445153,DB0882710019211_,1.253705377,0.442505692,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lomitapide,DB08827
,91721,DB00973,10047700,114,3737,53,2968,0.001183522,1.708191292,1.217993093,2.42213801,0.006331953,DB0097310047700_,5.062146625,0.535435087,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ezetimibe,DB00973
,91722,DB00108,10061599,52,10142,11,3284,0.239696882,1.530618144,0.787837033,3.257159612,0.397516634,DB0010810061599_,0.9225185,0.425671669,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,natalizumab,DB00108
,91723,DB00437,10010774,161,6760,218,11328,0.047151282,1.237556896,1.000870773,1.527679681,0.119751818,DB0043710010774_,2.122333863,0.213139191,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,91724,DB01394,10010774,47,1393,19,1984,1.62113555401873e-06,3.521898404,2.017400235,6.383745272,2.2072803956168e-05,DB0139410010774_,10.7211643,1.259000163,female,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,colchicine,DB01394
,91725,DB04861,10012735,148,1817,79,1308,0.042774041,1.348494508,1.009437211,1.812245149,0.111274314,DB0486110012735_,2.195756825,0.298988791,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,nebivolol,DB04861
,91726,DB04861,10047895,35,1930,44,1343,0.010700252,0.553635727,0.342735479,0.888308358,0.037568482,DB0486110047895_,3.281589827,-0.591248341,NA,10047895,Weight decreased,10022891,Investigations,Inv,nebivolol,DB04861
,91727,DB01394,10053762,65,1375,59,1944,0.015937059,1.557354783,1.070086977,2.270467707,0.051678461,DB0139410053762_,2.962714193,0.44298873,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,colchicine,DB01394
,91728,DB04861,10053762,42,1923,37,1350,0.355339513,0.7969585,0.497044303,1.282530982,0.525103094,DB0486110053762_,0.644160666,-0.226952672,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,nebivolol,DB04861
,91730,DB01097,10003239,300,5965,73,1430,0.893258622,0.985200343,0.755159298,1.298985728,0.955497126,DB0109710003239_,0.045523523,-0.014910264,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,91731,DB01097,10010264,145,6120,43,1460,0.224163853,0.804477705,0.565812785,1.164327788,0.378721357,DB0109710010264_,0.97095455,-0.217562025,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,91732,DB01097,10023232,123,6142,36,1467,0.309846881,0.816084316,0.556115748,1.223910291,0.477309105,DB0109710023232_,0.739590978,-0.2032376,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,91733,DB01097,10028391,60,6205,10,1493,0.361142191,1.443604943,0.730986106,3.170549028,0.531055804,DB0109710028391_,0.632888171,0.367143418,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,91745,DB00641,10005555,51,14073,25,12450,0.015387124,1.80468768,1.097005495,3.041866314,0.050295412,DB0064110005555_,2.989841419,0.590387546,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,simvastatin,DB00641
,91771,DB00996,10061394,83,38870,25,22400,0.00357134,1.913228892,1.21039182,3.124678099,0.015574063,DB0099610061394_,4.162148404,0.648792334,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,91786,DB00571,10000081,52,5071,30,2579,0.638749315,0.881555494,0.550466801,1.435109047,0.775865779,DB0057110000081_,0.253775738,-0.126067325,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,propranolol,DB00571
,91789,DB00571,10002855,100,5023,36,2573,0.081737944,1.422838001,0.960011134,2.151275213,0.18127589,DB0057110002855_,1.707735152,0.352653469,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,propranolol,DB00571
,91794,DB00535,10033371,39,1165,12,634,0.100813634,1.768174641,0.89914511,3.736954051,0.21207574,DB0053510033371_,1.550811802,0.569947738,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,cefdinir,DB00535
,91797,DB00571,10033425,83,5040,23,2586,0.00934694,1.851472572,1.151736253,3.087375507,0.033720053,DB0057110033425_,3.389662578,0.615981307,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,propranolol,DB00571
,91799,DB00972,10033425,53,2451,15,1164,0.087678913,1.677796154,0.926981231,3.219055872,0.191296138,DB0097210033425_,1.653932591,0.517481119,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,azelastine,DB00972
,91801,DB00571,10048959,65,5058,27,2582,0.43757444,1.228863319,0.771239104,2.007930194,0.606035469,DB0057110048959_,0.500816765,0.206089611,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,91803,DB00959,10048959,124,7954,46,4956,0.002456977,1.679550496,1.186013056,2.414797601,0.011507778,DB0095910048959_,4.464732167,0.518526196,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,91804,DB00972,10048959,54,2450,12,1167,0.015935813,2.143091063,1.126943181,4.418987608,0.051677607,DB0097210048959_,2.962730715,0.762249209,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,azelastine,DB00972
,91805,DB01222,10048959,174,9100,71,5334,0.01100095,1.436455757,1.081534149,1.924917002,0.038408709,DB0122210048959_,3.259471039,0.3621788,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,91810,DB00421,10049438,43,8860,29,5223,0.625017401,0.874103705,0.532592069,1.4537022,0.76465359,DB0042110049438_,0.268332371,-0.134556255,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,91820,DB00264,10061284,48,29559,27,24865,0.104361121,1.495450515,0.914268443,2.4933675,0.217553498,DB0026410061284_,1.525310491,0.402427509,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,91849,DB01592,10055798,41,6235,32,3035,0.05957248,0.623692981,0.382396755,1.025409259,0.142665136,DB0159210055798_,1.947255104,-0.47209705,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,iron,DB01592
,91855,DB00230,10020642,275,19399,88,8563,0.008293295,1.379451717,1.079682476,1.776686789,0.030644444,DB0023010020642_,3.485303915,0.321686114,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,91856,DB00482,10020642,51,8208,30,3041,0.058787836,0.629865105,0.392768881,1.026390319,0.141226596,DB0048210020642_,1.957389618,-0.462249602,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,celecoxib,DB00482
,91865,DB00575,10001488,28,5216,64,3765,1.12997685504996e-07,0.31583443,0.194600416,0.500783163,2.02878699692541e-06,DB0057510001488_,13.10807248,-1.152537157,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,clonidine,DB00575
,91866,DB00181,10012218,40,9816,34,5837,0.147761969,0.69961745,0.431213932,1.140865038,0.280887307,DB0018110012218_,1.269801734,-0.357221594,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,91868,DB00181,10012587,35,9821,20,5851,1,1.042587522,0.584832949,1.907908264,1,DB0018110012587_,0,0.041705625,NA,10012587,Device leakage,10077536,Product issues,Prod,baclofen,DB00181
,91870,DB00575,10019303,39,5205,26,3803,0.80134463,1.095978897,0.64920996,1.878480958,0.892535197,DB0057510019303_,0.11368933,0.091647934,NA,10019303,Heart rate increased,10022891,Investigations,Inv,clonidine,DB00575
,91875,DB00181,10070617,55,9801,60,5811,0.001314696,0.543536175,0.36943549,0.798254659,0.006893432,DB0018110070617_,4.977186235,-0.609659015,NA,10070617,Device infusion issue,10077536,Product issues,Prod,baclofen,DB00181
,91877,DB00635,10023230,106,32947,47,23747,0.005167944,1.625535062,1.142141281,2.344244946,0.021001764,DB0063510023230_,3.863148864,0.48583703,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,91878,DB00635,10058080,146,32907,128,23666,0.11042592,0.820320487,0.642144763,1.048966058,0.226708218,DB0063510058080_,1.484091471,-0.198060178,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,91885,DB00471,10003285,63,14126,19,5446,0.388871097,1.278302859,0.754398322,2.263880911,0.558742178,DB0047110003285_,0.582067132,0.245533307,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,91890,DB00316,10006451,722,64752,203,36750,1.12855128196793e-20,2.018561852,1.724118971,2.371585144,1.26498807874316e-18,DB0031610006451_,41.21146898,0.702385303,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,91891,DB00343,10006451,151,8585,40,5055,2.31206810728087e-06,2.222669736,1.556493142,3.239501468,3.00706136565451e-05,DB0034310006451_,10.41196215,0.798709057,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,diltiazem,DB00343
,91892,DB00264,10047340,97,29510,39,24853,6.35199218916893e-05,2.094604972,1.430000843,3.121881316,0.000540418,DB0026410047340_,7.523167802,0.739364978,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,metoprolol,DB00264
,91893,DB00264,10057362,74,29533,68,24824,0.613470323,0.914719472,0.648854007,1.29123355,0.755201734,DB0026410057362_,0.280770368,-0.089137849,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,91903,DB01240,10007811,54,5697,7,1569,0.05985761,2.124334742,0.96115939,5.546148438,0.14322779,DB0124010007811_,1.943318978,0.753458691,NA,10007811,Catheter site related reaction,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,91905,DB00682,10022086,90,19369,34,16330,4.02252094049095e-05,2.231631682,1.487858129,3.418328268,0.000366489,DB0068210022086_,7.911543125,0.802733014,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,91906,DB00927,10022086,38,7459,16,5000,0.127059665,1.591978705,0.865661666,3.061728786,0.251497669,DB0092710022086_,1.380321557,0.464977711,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,91908,DB06403,10022086,57,21414,8,6653,0.028489986,2.213462796,1.050120628,5.375551331,0.081357954,DB0640310022086_,2.508896669,0.794558165,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,91909,DB00374,10052264,187,17529,48,5676,0.169409612,1.261474494,0.912872598,1.773134302,0.310114328,DB0037410052264_,1.170814248,0.23228127,NA,10052264,Catheter site erythema,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,91911,DB00682,10052264,180,19279,40,16324,9.80305698254491e-18,3.810030964,2.690545956,5.51398652,8.20615773204436e-16,DB0068210052264_,34.73647667,1.337637316,female,10052264,Catheter site erythema,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,91919,DB00996,10064687,44,38909,25,22400,1,1.013236071,0.606456535,1.728152384,1,DB0099610064687_,0,0.01314924,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,91920,DB00374,10067996,73,17643,18,5706,0.330374475,1.311598325,0.774072019,2.337283191,0.499074314,DB0037410067996_,0.695000268,0.271246489,NA,10067996,Catheter site swelling,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,91922,DB00682,10067996,65,19394,11,16353,1.02977754407348e-08,4.982301062,2.608089217,10.47174235,2.30953095102145e-07,DB0068210067996_,15.2810512,1.605891845,female,10067996,Catheter site swelling,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,91925,DB01240,10067996,124,5627,18,1558,0.009538872,1.907189727,1.153763002,3.334651349,0.03429245,DB0124010067996_,3.37283007,0.645630812,NA,10067996,Catheter site swelling,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,91930,DB09072,10000059,64,6407,31,2504,0.35865616,0.806852445,0.516251393,1.285487099,0.528390391,DB0907210000059_,0.637919891,-0.214614471,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,sodium oxybate,DB09072
,91932,DB00455,10013946,91,9310,25,5093,0.00169133,1.991162972,1.265443489,3.240444699,0.008469541,DB0045510013946_,4.771278999,0.688718876,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,91936,DB01104,10013946,87,15376,24,7262,0.018735119,1.712031002,1.078046887,2.816431157,0.058691687,DB0110410013946_,2.835457178,0.537680386,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,91937,DB09072,10013946,36,6435,16,2519,0.645615741,0.880792602,0.475455034,1.703220527,0.78127203,DB0907210013946_,0.24683188,-0.126933093,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,sodium oxybate,DB09072
,91939,DB00455,10061428,160,9241,94,5024,0.551628284,0.925391983,0.711117684,1.209820812,0.705593308,DB0045510061428_,0.348716258,-0.077537866,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,loratadine,DB00455
,91962,DB08932,10017955,267,19176,89,6508,0.951078018,1.01815259,0.796680269,1.311443953,0.989279213,DB0893210017955_,0.010778669,0.017989799,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,91963,DB00820,10038063,43,11872,23,5793,0.696035079,0.912270918,0.537093994,1.587506003,0.817063709,DB0082010038063_,0.202038207,-0.091818274,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,91974,DB00695,10003997,48,28001,46,20482,0.209900399,0.763289261,0.49845018,1.170040693,0.36103995,DB0069510003997_,1.018766662,-0.270118209,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,furosemide,DB00695
,91981,DB01137,10038695,89,7683,95,5498,0.008282245,0.670443645,0.495288026,0.906798815,0.030618635,DB0113710038695_,3.486146473,-0.399815629,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,91984,DB00390,10047302,34,4111,63,3238,4.89799045775176e-05,0.425123125,0.270858826,0.65700578,0.000434288,DB0039010047302_,7.741802918,-0.855376445,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,digoxin,DB00390
,91986,DB00695,10047302,68,27981,93,20435,8.17480422239639e-05,0.534013611,0.384548663,0.738363931,0.000671798,DB0069510047302_,7.305552212,-0.627333952,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,furosemide,DB00695
,91995,DB00656,10064355,48,11965,34,6585,0.297817294,0.777001123,0.48985165,1.244709896,0.463710427,DB0065610064355_,0.768495002,-0.252313484,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,91996,DB00695,10064355,126,27923,91,20437,0.945187377,1.013408065,0.767287904,1.342856781,0.983794334,DB0069510064355_,0.016338414,0.013318973,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,91999,DB01104,10064355,60,15403,38,7248,0.158874515,0.742971943,0.486285692,1.147786584,0.295994178,DB0110410064355_,1.217415493,-0.297096997,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,92010,DB00921,10011906,93,5752,102,4801,0.05955718,0.76104369,0.566781011,1.020826513,0.142649429,DB0092110011906_,1.947365204,-0.273064511,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,92018,DB00047,10000060,58,9227,37,8481,0.098966549,1.440796451,0.936704454,2.241293627,0.209295659,DB0004710000060_,1.564007392,0.365196052,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,92019,DB00758,10000060,43,8257,41,10033,0.273774659,1.274339038,0.810367333,2.006598963,0.436839607,DB0075810000060_,0.828189183,0.242427643,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,92021,DB01409,10000060,45,5986,26,3940,0.628412593,1.139215626,0.686577268,1.926792248,0.767717459,DB0140910000060_,0.264333505,0.130339978,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,tiotropium,DB01409
,92024,DB00758,10005191,42,8258,28,10046,0.015584813,1.82469078,1.103651652,3.059464625,0.050799455,DB0075810005191_,2.979869655,0.601410537,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,clopidogrel,DB00758
,92028,DB00421,10042682,38,8865,16,5236,0.323080791,1.402731544,0.762836351,2.697442804,0.49149185,DB0042110042682_,0.710309921,0.338421439,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,92030,DB01136,10042682,48,9836,20,11095,0.000124999,2.707075913,1.575198196,4.819077247,0.000965362,DB0113610042682_,6.943007259,0.995869053,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,92036,DB00394,10003553,69,1570,35,759,0.831099805,0.953085861,0.619406628,1.489455754,0.911689935,DB0039410003553_,0.092455331,-0.048050284,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,beclomethasone dipropionate,DB00394
,92037,DB00425,10003553,80,12615,10,7474,3.78374198827969e-08,4.739297383,2.44593783,10.26887423,7.49195165061631e-07,DB0042510003553_,14.10426632,1.555888893,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,92039,DB00927,10003553,56,7441,10,5006,1.35334000827548e-05,3.767111792,1.901966528,8.289780966,0.000141667,DB0092710003553_,8.862032494,1.326308605,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,92040,DB00043,10037087,273,6140,79,2221,0.095397735,1.249969518,0.964839083,1.634554138,0.203855898,DB0004310037087_,1.590341917,0.223119166,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,omalizumab,DB00043
,92042,DB00654,10037087,62,3754,34,2564,0.346179632,1.245435522,0.804286827,1.958137008,0.515589753,DB0065410037087_,0.662443882,0.219485286,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,latanoprost,DB00654
,92043,DB00043,10043521,63,6350,16,2284,0.248915605,1.416169733,0.806235795,2.632618558,0.408360172,DB0004310043521_,0.895605721,0.347955856,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omalizumab,DB00043
,92055,DB01409,10046735,48,5983,25,3941,0.400923409,1.264665814,0.763022465,2.144193823,0.570747843,DB0140910046735_,0.560807772,0.234807908,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,tiotropium,DB01409
,92057,DB00394,10047924,39,1600,13,781,0.295258615,1.46416116,0.759759402,3.007440622,0.461174359,DB0039410047924_,0.773979088,0.381282491,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,beclomethasone dipropionate,DB00394
,92058,DB00476,10047924,55,17202,11,6166,0.091927161,1.792272922,0.927025236,3.800379602,0.198301635,DB0047610047924_,1.617965998,0.583484603,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,92061,DB00668,10047924,72,10019,22,4281,0.176843816,1.398421015,0.855913317,2.371218424,0.319847223,DB0066810047924_,1.139911825,0.335343753,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,92065,DB00425,10061623,68,12627,52,7432,0.156336967,0.769707548,0.527891399,1.127911581,0.292498909,DB0042510061623_,1.229294341,-0.261744644,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,92066,DB00476,10061623,103,17154,35,6142,0.846689541,1.053672609,0.710874718,1.595532633,0.922998542,DB0047610061623_,0.080127624,0.052281784,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,92070,DB00927,10061623,33,7464,26,4990,0.594681118,0.848550027,0.491506741,1.47931343,0.740481451,DB0092710061623_,0.300454695,-0.164226236,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,92076,DB00448,10003553,38,5107,12,3112,0.056025428,1.929497584,0.985215321,4.062715649,0.136152772,DB0044810003553_,1.9939777,0.65725965,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lansoprazole,DB00448
,92077,DB00678,10003553,96,15503,30,10694,8.08355987002801e-05,2.207292547,1.450316315,3.448729622,0.000665132,DB0067810003553_,7.315525258,0.791766672,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,92090,DB00051,10025650,68,25663,44,11376,0.051813321,0.685079124,0.461766268,1.025685203,0.128452076,DB0005110025650_,2.052199391,-0.378220938,NA,10025650,Malignant melanoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,adalimumab,DB00051
,92094,DB00316,10025650,42,65432,25,36928,0.898836436,0.948146163,0.564497963,1.623621784,0.956490275,DB0031610025650_,0.044484657,-0.053246608,NA,10025650,Malignant melanoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,92098,DB00863,10025482,384,10289,114,5726,1.21266677593477e-09,1.874516034,1.513069487,2.337095943,3.31685184239806e-08,DB0086310025482_,17.22166465,0.628350511,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,92100,DB01015,10025482,224,9663,128,9253,3.32147160609714e-06,1.675694705,1.339971253,2.102934643,4.13767209318784e-05,DB0101510025482_,10.09279213,0.516227828,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,92101,DB11065,10025482,87,3099,63,2625,0.362205382,1.169700576,0.83236899,1.651554766,0.531875334,DB1106510025482_,0.631346152,0.156747798,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,pancrelipase amylase,DB11065
,92104,DB00230,10051118,173,19501,77,8574,0.94503848,0.987829723,0.75001945,1.311145003,0.983677576,DB0023010051118_,0.016457103,-0.012244942,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,92113,DB00887,10016322,45,2296,18,1797,0.014972028,1.956347364,1.105645237,3.604107846,0.049243081,DB0088710016322_,3.010986412,0.671079145,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,92115,DB00697,10042209,51,6045,8,1798,0.117798599,1.895957046,0.890992997,4.635366276,0.237886922,DB0069710042209_,1.435959836,0.639723749,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,tizanidine,DB00697
,92118,DB06616,10003239,32,929,35,768,0.263559063,0.755962165,0.448483139,1.270197771,0.425400674,DB0661610003239_,0.854723791,-0.279763951,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,bosutinib,DB06616
,92122,DB01076,10008796,40,25707,53,25530,0.178087153,0.749527312,0.484199831,1.152039236,0.321410382,DB0107610008796_,1.135036523,-0.288312522,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,92130,DB01076,10023126,21,25726,34,25549,0.080380442,0.61340707,0.338200196,1.088097382,0.179044346,DB0107610023126_,1.720121761,-0.488726502,NA,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,atorvastatin,DB01076
,92134,DB00433,10028411,66,7590,43,5977,0.383443257,1.208678481,0.809601469,1.821171083,0.553476442,DB0043310028411_,0.59153609,0.189527598,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,prochlorperazine,DB00433
,92135,DB01069,10028411,77,6623,24,2371,0.649593628,1.148546765,0.71628173,1.904344513,0.784352452,DB0106910028411_,0.242896804,0.13849746,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,promethazine,DB01069
,92139,DB06616,10061428,35,926,19,784,0.128828917,1.559237063,0.859873983,2.910198942,0.253944033,DB0661610061428_,1.37064138,0.444196639,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,bosutinib,DB06616
,92141,DB01268,10037660,51,2092,76,3054,0.927454362,0.979636827,0.670136438,1.421904021,0.969463847,DB0126810037660_,0.031012096,-0.020573361,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,92146,DB00959,10048294,44,8034,46,4956,0.016138164,0.590105546,0.380691664,0.913657561,0.052172884,DB0095910048294_,2.953192389,-0.527453867,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,methylprednisolone,DB00959
,92147,DB00959,10054236,31,8047,27,4975,0.22275295,0.709872835,0.409433691,1.237766691,0.376882706,DB0095910054236_,0.975821264,-0.342669431,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,92148,DB00422,10000087,36,3399,27,2922,0.613966536,1.146194695,0.674895253,1.968144983,0.755564886,DB0042210000087_,0.280289617,0.136447495,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,methylphenidate,DB00422
,92171,DB00422,10046735,35,3400,26,2923,0.60763851,1.157269565,0.675175329,2.007201633,0.750518219,DB0042210046735_,0.286991352,0.146063407,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,methylphenidate,DB00422
,92188,DB00482,10069326,40,8219,18,3053,0.553397564,0.825442952,0.461626798,1.532222837,0.707011279,DB0048210069326_,0.346708661,-0.191835125,NA,10069326,Product substitution issue,10077536,Product issues,Prod,celecoxib,DB00482
,92190,DB00285,10022998,77,10874,26,3692,1,1.005517882,0.636108355,1.637231613,1,DB0028510022998_,0,0.005502714,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,92193,DB00285,10069326,50,10901,17,3701,1,0.99855932,0.565287617,1.849202569,1,DB0028510069326_,0,-0.001441719,NA,10069326,Product substitution issue,10077536,Product issues,Prod,venlafaxine,DB00285
,92206,DB01255,10019211,113,2020,61,1517,0.041454705,1.391056054,1.002332573,1.946064399,0.108643195,DB0125510019211_,2.219686202,0.330063209,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lisdexamfetamine,DB01255
,92212,DB00363,10039424,45,4583,58,6830,0.480819028,1.156240626,0.764046772,1.739934033,0.645570217,DB0036310039424_,0.437621295,0.145173903,NA,10039424,Salivary hypersecretion,10017947,Gastrointestinal disorders,Gastr,clozapine,DB00363
,92215,DB00207,10070863,37,9043,16,5439,0.320399845,1.39084519,0.754039425,2.680784911,0.488583275,DB0020710070863_,0.716245351,0.329911612,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,azithromycin,DB00207
,92216,DB00363,10070863,71,4557,67,6821,0.008547168,1.586069346,1.117281305,2.25377213,0.031394959,DB0036310070863_,3.461107955,0.461258846,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,clozapine,DB00363
,92219,DB00158,10000496,40,16775,11,8093,0.101294085,1.754306572,0.882850947,3.793512042,0.212788413,DB0015810000496_,1.547456971,0.562073663,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,92224,DB00563,10000496,72,46574,19,15329,0.465910278,1.247225765,0.743726787,2.191134201,0.632699667,DB0056310000496_,0.45775943,0.220921697,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,92225,DB00588,10000496,38,16486,14,8454,0.309111084,1.391864853,0.736678049,2.782824846,0.476468837,DB0058810000496_,0.741352958,0.330644469,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,92251,DB00563,10040831,87,46559,20,15328,0.177853848,1.432058191,0.872766085,2.459865509,0.321139194,DB0056310040831_,1.135880623,0.359112704,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,92253,DB08868,10015958,97,9105,18,2493,0.138498751,1.475447136,0.884058395,2.598876286,0.267679387,DB0886810015958_,1.317965331,0.388961087,NA,10015958,Eye pain,10015919,Eye disorders,Eye,fingolimod,DB08868
,92255,DB08868,10030942,75,9127,17,2494,0.609608225,1.205516813,0.703546181,2.181892563,0.751961715,DB0886810030942_,0.285069867,0.186908366,NA,10030942,Optic neuritis,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,92256,DB08868,10047571,320,8882,96,2415,0.395112299,0.906321561,0.715963514,1.155972702,0.564952771,DB0886810047571_,0.571013143,-0.098361112,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,fingolimod,DB08868
,92258,DB00281,10016173,265,11193,103,5568,0.038134631,1.279883247,1.013144591,1.626751333,0.101866744,DB0028110016173_,2.284089748,0.24676886,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,lidocaine,DB00281
,92260,DB01109,10016173,84,4328,45,4225,0.001314659,1.822109928,1.250568031,2.685598058,0.006893432,DB0110910016173_,4.977186235,0.599995131,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,heparin,DB01109
,92262,DB09140,10016173,226,3515,88,1710,0.093693955,1.249382983,0.965389596,1.628209745,0.201254033,DB0914010016173_,1.603187323,0.222649816,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,oxygen,DB09140
,92263,DB00158,10024855,95,16720,48,8056,0.788703546,0.953600787,0.666358462,1.38042331,0.885552887,DB0015810024855_,0.121543098,-0.047510157,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,92264,DB00207,10024855,31,9049,30,5425,0.064160818,0.61954483,0.362304028,1.060704179,0.150941295,DB0020710024855_,1.89086429,-0.478770216,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,92265,DB00281,10024855,62,11396,43,5628,0.095882248,0.712065538,0.474264998,1.077929394,0.204608474,DB0028110024855_,1.586657009,-0.339585324,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,92266,DB00404,10024855,202,19690,73,9789,0.020375624,1.375690611,1.046420393,1.82551232,0.062713499,DB0040410024855_,2.769178555,0.318955868,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,92267,DB00448,10024855,40,5105,17,3107,0.272528471,1.431985254,0.791989229,2.698747278,0.435505418,DB0044810024855_,0.831248041,0.359061771,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,lansoprazole,DB00448
,92268,DB00588,10024855,132,16392,47,8421,0.032193898,1.442785564,1.025813955,2.060339476,0.089520868,DB0058810024855_,2.41328352,0.366575665,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,92270,DB01050,10024855,94,18014,41,9330,0.412793046,1.187422361,0.813765589,1.759749116,0.582189473,DB0105010024855_,0.540959329,0.171784875,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,92271,DB01075,10024855,147,19801,73,11024,0.438487333,1.121117434,0.84028442,1.506949091,0.606900086,DB0107510024855_,0.499391104,0.114325897,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,92272,DB01109,10024855,22,4390,30,4240,0.265683428,0.708307988,0.388636267,1.272016238,0.427765698,DB0110910024855_,0.849179668,-0.344876269,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,heparin,DB01109
,92273,DB01137,10024855,46,7726,25,5568,0.279138263,1.326029286,0.796789219,2.255132511,0.442970945,DB0113710024855_,0.814251099,0.282188977,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,92277,DB00005,10017964,50,128032,22,42397,0.275620281,0.752600983,0.44737513,1.305319276,0.438888185,DB0000510017964_,0.823510603,-0.284220095,NA,10017964,Gastrointestinal infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,92281,DB01164,10013573,38,6486,25,7911,0.016001473,1.853845029,1.089044481,3.208234281,0.051835298,DB0116410013573_,2.959683941,0.617261876,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,calcium chloride,DB01164
,92294,DB01590,10035664,135,4603,79,2788,0.830436417,1.035040921,0.775078228,1.389892892,0.911076287,DB0159010035664_,0.093128645,0.034440963,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,everolimus,DB01590
,92296,DB01222,10022611,31,9243,22,5383,0.478736954,0.820656803,0.459574484,1.489190338,0.643975376,DB0122210022611_,0.44009479,-0.19765028,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,92298,DB00635,10025256,51,33002,43,23751,0.464834328,0.853583714,0.557472591,1.312449209,0.631757386,DB0063510025256_,0.459249842,-0.158311658,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,prednisone,DB00635
,92305,DB00175,10012601,32,8099,28,6078,0.601791737,0.857683798,0.499613072,1.48017867,0.746013432,DB0017510012601_,0.293011674,-0.153519781,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,pravastatin,DB00175
,92306,DB00437,10012601,20,6901,45,11501,0.305102927,0.740709429,0.413959634,1.281658284,0.47189564,DB0043710012601_,0.75099742,-0.300146864,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,allopurinol,DB00437
,92309,DB11089,10012601,42,10133,27,8380,0.333835562,1.286427197,0.774103067,2.171713284,0.502914329,DB1108910012601_,0.687335443,0.251868762,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,92316,DB00047,10038428,38,9247,57,8461,0.01795295,0.610021908,0.393217258,0.936886504,0.056748937,DB0004710038428_,2.869118346,-0.494260408,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,insulin glargine,DB00047
,92317,DB00175,10038428,34,8097,28,6078,0.79728209,0.911508309,0.535833482,1.562233937,0.890347732,DB0017510038428_,0.116143182,-0.092654569,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,pravastatin,DB00175
,92319,DB00722,10038428,95,25308,86,25946,0.413566059,1.132495328,0.836525967,1.535031395,0.582935642,DB0072210038428_,0.53967849,0.124423453,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,92322,DB11089,10038428,46,10129,31,8376,0.422615479,1.227046945,0.760746622,2.003772232,0.591582898,DB1108910038428_,0.524953457,0.204610425,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,docusate,DB11089
,92331,DB00367,10003549,58,22742,6,461,0.001775704,0.195988497,0.084221755,0.558726858,0.008818133,DB0036710003549_,4.730945155,-1.629699312,male,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,levonorgestrel,DB00367
,92332,DB00669,10003549,84,6293,16,1081,0.670325061,0.901821116,0.521817489,1.656136807,0.800013359,DB0066910003549_,0.223126852,-0.103339098,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,92333,DB00285,10017577,129,10822,51,3667,0.344177736,0.85711536,0.613802971,1.212527068,0.513507125,DB0028510017577_,0.666491374,-0.154182761,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,92335,DB00455,10017577,111,9290,45,5073,0.109059109,1.346948819,0.942789412,1.952815894,0.224616879,DB0045510017577_,1.493359088,0.2978419,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,92343,DB00338,10048592,52,33622,32,22240,0.823732712,1.074901543,0.678801796,1.726134033,0.906573661,DB0033810048592_,0.098082993,0.072229069,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,92351,DB00285,10049848,80,10871,20,3698,0.249086447,1.360635997,0.824019258,2.349006201,0.408490522,DB0028510049848_,0.895286567,0.307952235,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,92353,DB00455,10049848,60,9341,19,5099,0.043962665,1.72375,1.013162717,3.062334909,0.113523789,DB0045510049848_,2.175742867,0.54450215,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,92354,DB00588,10049848,118,16406,45,8423,0.096820592,1.34627614,0.946368971,1.944650905,0.206008764,DB0058810049848_,1.579836567,0.297342366,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,92382,DB00203,10052270,153,13725,29,8909,1.21475917450183e-11,3.424430521,2.288761122,5.289520855,4.58434241231597e-10,DB0020310052270_,21.50320426,1.230935187,female,10052270,Catheter site pruritus,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,92386,DB00203,10057688,113,13765,28,8910,9.71534352091874e-07,2.612184855,1.712846229,4.108449404,1.39430960659213e-05,DB0020310057688_,11.18052608,0.96018698,NA,10057688,Catheter site discharge,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,92388,DB00682,10038980,21,19438,40,16324,0.001920089,0.440901447,0.246877749,0.766153669,0.009415083,DB0068210038980_,4.66544233,-0.818933905,NA,10038980,Retroperitoneal haemorrhage,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,92394,DB00295,10000059,120,14543,53,9549,0.015574385,1.486627724,1.066230011,2.096996312,0.050771761,DB0029510000059_,2.980414974,0.396510283,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,92399,DB00404,10061818,154,19738,66,9796,0.350208902,1.158019729,0.861564519,1.57118691,0.519830825,DB0040410061818_,0.654251857,0.146711416,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,92401,DB08877,10008479,23,3266,37,3192,0.068991012,0.607586996,0.343847182,1.052605604,0.159506444,DB0887710008479_,1.835670958,-0.49825991,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,92405,DB00868,10010264,50,2934,26,1620,0.903944497,1.061812925,0.645674679,1.784316063,0.957442354,DB0086810010264_,0.043489764,0.059977754,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,benzonatate,DB00868
,92423,DB00682,10005724,141,19318,29,16335,3.75459767840319e-15,4.111061496,2.739890897,6.365111368,2.34139027228536e-13,DB0068210005724_,29.08286132,1.413681267,female,10005724,Blood potassium decreased,10022891,Investigations,Inv,warfarin,DB00682
,92424,DB00820,10005724,103,11812,17,5799,5.16903333341924e-06,2.974380225,1.768237516,5.307223429,6.09683828444805e-05,DB0082010005724_,9.705155142,1.09003569,female,10005724,Blood potassium decreased,10022891,Investigations,Inv,tadalafil,DB00820
,92427,DB00722,10003119,30,25373,43,25989,0.161693956,0.714619736,0.432722787,1.166279313,0.299682732,DB0072210003119_,1.205030923,-0.336004715,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,lisinopril,DB00722
,92429,DB05259,10022000,65,11205,15,2713,1,1.04921813,0.590745716,1.984118238,1,DB0525910022000_,0,0.048045249,NA,10022000,Influenza,10021881,Infections and infestations,Infec,glatiramer,DB05259
,92440,DB13961,10046735,84,9373,39,6375,0.052581352,1.464893164,0.989212204,2.203236493,0.129866183,DB1396110046735_,2.041250723,0.381782314,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,fish oil,DB13961
,92442,DB01373,10053425,92,22628,11,7370,0.000530354,2.724109168,1.452469404,5.65069837,0.003238553,DB0137310053425_,5.732628713,1.002141464,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,92443,DB13961,10053425,78,9379,15,6399,6.28358657938968e-07,3.547541708,2.022390879,6.645781469,9.49218811719872e-06,DB1396110053425_,11.5650414,1.266254887,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,92451,DB00285,10029216,68,10883,13,3705,0.054905562,1.780602645,0.973581511,3.517938466,0.134156885,DB0028510029216_,2.008745382,0.576951872,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,92458,DB00761,10003598,39,15268,24,8601,0.792933125,0.915424555,0.536442944,1.592478741,0.88777302,DB0076110003598_,0.119039177,-0.088367327,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,92485,DB00169,10007632,35,38656,15,18160,0.879724566,1.096160337,0.583195096,2.160843428,0.949457398,DB0016910007632_,0.051864617,0.09181347,NA,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,92486,DB00264,10007632,46,29561,23,24869,0.040312377,1.682534607,0.998798555,2.909085288,0.10626553,DB0026410007632_,2.241814316,0.520301351,NA,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,metoprolol,DB00264
,92499,DB00264,10013554,40,29567,18,24874,0.025287413,1.869456391,1.047045675,3.465334751,0.074133354,DB0026410013554_,2.601889724,0.625647689,NA,10013554,Diverticulum,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,92500,DB00316,10013554,58,65416,17,36936,0.015801574,1.926380215,1.106060535,3.529315595,0.051353162,DB0031610013554_,2.969028768,0.655642706,NA,10013554,Diverticulum,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,92501,DB00338,10013554,41,33633,17,22255,0.10870689,1.595853409,0.886604241,2.99680428,0.224080323,DB0033810013554_,1.495750708,0.467408646,NA,10013554,Diverticulum,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,92507,DB00695,10013554,34,28015,20,20508,0.492047648,1.244455797,0.695861856,2.282322138,0.65501299,DB0069510013554_,0.423100211,0.218698324,NA,10013554,Diverticulum,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,92517,DB00264,10013990,59,29548,72,24820,0.035038725,0.688336062,0.479242736,0.98525225,0.095469358,DB0026410013990_,2.348949943,-0.373478098,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,92522,DB00695,10013990,80,27969,60,20468,0.931772028,0.975738516,0.689120778,1.387977722,0.972739207,DB0069510013990_,0.027639262,-0.024560643,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,92523,DB00761,10013990,45,15262,21,8604,0.522642199,1.20799709,0.704266901,2.136523229,0.681143873,DB0076110013990_,0.383981728,0.18896369,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,potassium chloride,DB00761
,92526,DB00863,10013990,32,10641,18,5822,1,0.972655615,0.529199623,1.842090096,1,DB0086310013990_,0,-0.027725201,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,ranitidine,DB00863
,92570,DB00437,10015150,45,6876,59,11487,0.224229631,1.274143005,0.843754205,1.912639955,0.378797286,DB0043710015150_,0.970754083,0.2422738,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,92571,DB00471,10015150,138,14051,50,5415,0.744186913,1.063650142,0.76316525,1.503378664,0.853891785,DB0047110015150_,0.157950808,0.061706523,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,92573,DB00761,10015150,133,15174,48,8577,0.008053156,1.566166757,1.116742959,2.228936813,0.029948671,DB0076110015150_,3.508270336,0.448631078,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,potassium chloride,DB00761
,92576,DB00863,10015150,141,10532,54,5786,0.02383404,1.434445066,1.039361036,2.004566307,0.070848486,DB0086310015150_,2.647211683,0.360778061,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,92577,DB00864,10015150,46,6823,36,8356,0.045461563,1.564803299,0.988496818,2.494775335,0.116449269,DB0086410015150_,2.150299559,0.447760128,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,tacrolimus,DB00864
,92578,DB01076,10015150,172,25575,141,25442,0.099981496,1.213507967,0.964911528,1.52823827,0.210763784,DB0107610015150_,1.557017281,0.193515312,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,92581,DB00437,10018867,11,6910,53,11493,0.000644638,0.345219254,0.162505735,0.669270561,0.003825332,DB0043710018867_,5.566110144,-1.063575544,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,allopurinol,DB00437
,92590,DB00722,10019022,32,25371,27,26005,0.515418839,1.214795251,0.704870481,2.108313415,0.675204848,DB0072210019022_,0.392739155,0.194575545,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,92642,DB00264,10029148,69,29538,94,24798,0.002660396,0.616263027,0.444771805,0.850239997,0.012258483,DB0026410029148_,4.40153713,-0.484081415,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,92643,DB00437,10029148,15,6906,47,11499,0.034813639,0.531423756,0.275784511,0.96815398,0.09505807,DB0043710029148_,2.353267315,-0.632195542,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,allopurinol,DB00437
,92644,DB00471,10029148,53,14136,15,5450,0.343145859,1.362188122,0.755691038,2.604473175,0.512447526,DB0047110029148_,0.668556962,0.30909232,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,montelukast,DB00471
,92646,DB00656,10029148,45,11968,20,6599,0.516435063,1.240652241,0.716987526,2.219948254,0.676073958,DB0065610029148_,0.391452804,0.215637243,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,trazodone,DB00656
,92647,DB00695,10029148,70,27979,59,20469,0.423478718,0.867986271,0.604766098,1.249525872,0.592286594,DB0069510029148_,0.52376465,-0.141579381,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,92648,DB00761,10029148,52,15255,29,8596,1,1.010390892,0.629113958,1.652001347,1,DB0076110029148_,0,0.010337278,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,potassium chloride,DB00761
,92651,DB00863,10029148,34,10639,20,5820,0.777571883,0.92997981,0.51962446,1.706640485,0.878740499,DB0086310029148_,0.129265648,-0.072592403,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,ranitidine,DB00863
,92653,DB01076,10029148,63,25684,92,25491,0.019464925,0.679645473,0.485042671,0.947120936,0.060527098,DB0107610029148_,2.804664107,-0.38618398,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,92656,DB00136,10030124,31,2061,23,1659,0.784877963,1.084934499,0.609771743,1.956513548,0.883247992,DB0013610030124_,0.124149266,0.081519616,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,calcitriol,DB00136
,92657,DB00656,10030124,77,11936,49,6570,0.455176414,0.864983092,0.596030326,1.26575704,0.622752032,DB0065610030124_,0.473606862,-0.145045319,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,92660,DB00863,10030124,141,10532,66,5774,0.306481326,1.171195311,0.866687974,1.596631495,0.473500977,DB0086310030124_,0.747601302,0.158024861,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,92661,DB00864,10030124,50,6819,53,8339,0.487755646,1.153672556,0.766873541,1.733310773,0.651472708,DB0086410030124_,0.428519775,0.142950381,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,92692,DB00471,10042674,113,14076,25,5440,0.009882241,1.74685018,1.123460476,2.815940581,0.035225754,DB0047110042674_,3.345977805,0.557814269,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,92693,DB00656,10042674,73,11940,22,6597,0.012993142,1.83328222,1.123761288,3.104877646,0.043861135,DB0065610042674_,3.126726662,0.606107923,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,92694,DB00761,10042674,156,15151,72,8553,0.166122888,1.22306555,0.918093892,1.642693435,0.305598217,DB0076110042674_,1.185484057,0.201360453,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,92700,DB00169,10043224,53,38638,16,18159,0.123090491,1.556790049,0.876095019,2.918455932,0.245834847,DB0016910043224_,1.403095321,0.44262604,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,92701,DB00338,10043224,39,33635,17,22255,0.17233504,1.517918413,0.838579805,2.862339482,0.313917292,DB0033810043224_,1.158625728,0.417339931,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,92705,DB00695,10043224,47,28002,15,20513,0.004289567,2.295279321,1.260631523,4.420701919,0.018080703,DB0069510043224_,4.012910043,0.830854545,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,92706,DB00722,10043224,32,25371,19,26013,0.067882101,1.726798668,0.949160521,3.225383225,0.15752459,DB0072210043224_,1.848173708,0.546269213,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,92734,DB00471,10046571,304,13885,43,5422,4.51237230632411e-12,2.760436351,1.997510764,3.899692876,1.83461262291925e-10,DB0047110046571_,22.41901758,1.015388765,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,montelukast,DB00471
,92753,DB00005,10028164,40,128042,13,42406,1,1.019045976,0.533865015,2.076816487,1,DB0000510028164_,0,0.018866871,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,etanercept,DB00005
,92768,DB00250,10013709,49,777,29,781,0.027497917,1.697801193,1.039039893,2.818860814,0.079101862,DB0025010013709_,2.537018862,0.529333998,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dapsone,DB00250
,92769,DB00250,10016256,35,791,43,767,0.353516042,0.789373419,0.484697199,1.277927796,0.523310853,DB0025010016256_,0.647579627,-0.236515788,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dapsone,DB00250
,92772,DB01156,10048334,46,13576,17,6311,0.49827056,1.257823153,0.706852671,2.342370212,0.660264011,DB0115610048334_,0.415115508,0.22938257,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,92776,DB01156,10061623,69,13553,31,6297,0.914673686,1.034124574,0.666936873,1.636806364,0.961865977,DB0115610061623_,0.038880155,0.033555247,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,92778,DB00203,10014011,66,13812,25,8913,0.023530001,1.703574702,1.059564967,2.820212992,0.070123138,DB0020310014011_,2.657502467,0.532728809,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,92779,DB00559,10014011,40,9619,10,3296,0.420387191,1.370566656,0.672612067,3.076791132,0.58932679,DB0055910014011_,0.528774427,0.315224272,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,bosentan,DB00559
,92780,DB00972,10003988,49,2455,16,1163,0.228053812,1.450652764,0.806821271,2.745072108,0.383446549,DB0097210003988_,0.958555046,0.372013637,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,azelastine,DB00972
,92781,DB00425,10005750,108,12587,43,7441,0.027944142,1.484759843,1.032320412,2.169087043,0.080103797,DB0042510005750_,2.524432023,0.395253037,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,zolpidem,DB00425
,92783,DB01104,10005750,114,15349,62,7224,0.372649279,0.865402624,0.628859745,1.200499589,0.542394619,DB0110410005750_,0.611761463,-0.144560419,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,sertraline,DB01104
,92784,DB01234,10005750,199,31426,135,32753,0.000116932,1.536298137,1.227805004,1.927120749,0.000912174,DB0123410005750_,6.999680221,0.429375716,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,dexamethasone,DB01234
,92785,DB00158,10023547,51,16764,36,8068,0.085391741,0.681794491,0.435972034,1.076354235,0.187363573,DB0015810023547_,1.67470431,-0.383026999,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,folic acid,DB00158
,92786,DB00169,10023547,180,38511,116,18059,0.008607379,0.727635584,0.572615006,0.927697204,0.031589632,DB0016910023547_,3.454926309,-0.317954928,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,cholecalciferol,DB00169
,92787,DB00425,10023547,39,12656,30,7454,0.31780338,0.765687154,0.463119955,1.277448903,0.485728259,DB0042510023547_,0.722105949,-0.266981607,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,zolpidem,DB00425
,92790,DB00904,10023547,108,22961,78,14378,0.364808357,0.867042577,0.641482747,1.176452834,0.534400729,DB0090410023547_,0.626609293,-0.142667195,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,ondansetron,DB00904
,92793,DB01104,10023547,44,15419,25,7261,0.441224415,0.828829365,0.495781481,1.41426279,0.609404853,DB0110410023547_,0.495272449,-0.187740977,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,sertraline,DB01104
,92795,DB00924,10044565,108,10054,54,4197,0.298443092,0.834922657,0.595552232,1.182422179,0.464437209,DB0092410044565_,0.76692891,-0.180416185,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,92801,DB08880,10028245,96,3242,27,782,0.488527182,0.857638357,0.55014382,1.377784662,0.652072463,DB0888010028245_,0.427599583,-0.153572763,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,teriflunomide,DB08880
,92805,DB05676,10028836,82,47047,45,25284,0.925907456,0.979287063,0.672457099,1.442332343,0.968423967,DB0567610028836_,0.032085305,-0.020930459,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,92807,DB00531,10001052,34,7218,27,6489,0.700416138,1.132063938,0.662195296,1.953016051,0.819917974,DB0053110001052_,0.198550975,0.12404246,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclophosphamide,DB00531
,92809,DB00635,10001052,85,32968,98,23696,0.001565493,0.623431402,0.460448917,0.842607564,0.007961493,DB0063510001052_,4.833138711,-0.472516541,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,92820,DB00531,10021143,102,7150,101,6415,0.524040321,0.906092948,0.679851877,1.207734626,0.682137366,DB0053110021143_,0.382524225,-0.098613387,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclophosphamide,DB00531
,92821,DB00541,10021143,40,3094,66,4231,0.373882713,0.828800229,0.543584726,1.249683173,0.543692131,DB0054110021143_,0.609372128,-0.187776131,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vincristine,DB00541
,92824,DB00073,10035742,28,7378,54,6353,0.000500429,0.446505425,0.271977174,0.718430987,0.003093912,DB0007310035742_,5.778319032,-0.806303729,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rituximab,DB00073
,92825,DB00531,10035742,51,7201,49,6467,0.763604039,0.93475434,0.618050284,1.414903234,0.869133399,DB0053110035742_,0.140258657,-0.067471522,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclophosphamide,DB00531
,92826,DB00541,10035742,17,3117,35,4262,0.204452957,0.664172623,0.348251595,1.220357329,0.35446514,DB0054110035742_,1.037145274,-0.40921319,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vincristine,DB00541
,92835,DB00188,10016288,63,7823,100,8728,0.032987836,0.702897821,0.503709341,0.974586439,0.09124812,DB0018810016288_,2.394172888,-0.352543744,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,bortezomib,DB00188
,92842,DB00028,10046735,469,12989,282,5333,1.10769746234689e-06,0.682855687,0.585753698,0.797139039,1.56609714838837e-05,DB0002810046735_,11.06433883,-0.381471734,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,human immunoglobulin g,DB00028
,92847,DB00656,10000087,157,11856,42,6577,1.33750546711771e-05,2.073598042,1.4647202,2.993091598,0.000140177,DB0065610000087_,8.872606366,0.729285283,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,92849,DB01373,10000087,269,22451,45,7336,1.19337700142466e-05,1.953354859,1.418578086,2.744696466,0.000126688,DB0137310000087_,8.973784281,0.669548335,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,92851,DB13867,10000087,65,4485,21,2533,0.023975526,1.747975843,1.051741799,3.0183204,0.071192578,DB1386710000087_,2.642366701,0.558458457,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,fluticasone,DB13867
,92857,DB13867,10012735,274,4276,136,2418,0.243517503,1.139285903,0.918331777,1.41850672,0.401874593,DB1386710012735_,0.911615197,0.130401665,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fluticasone,DB13867
,92862,DB01610,10013968,24,917,45,1173,0.14053211,0.682342956,0.394479728,1.153788818,0.270575362,DB0161010013968_,1.307204617,-0.382222879,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,valganciclovir,DB01610
,92874,DB00188,10022000,68,7818,88,8740,0.376606862,0.863865283,0.619091474,1.200952283,0.546421352,DB0018810022000_,0.604364893,-0.146338445,NA,10022000,Influenza,10021881,Infections and infestations,Infec,bortezomib,DB00188
,92878,DB13867,10022000,74,4476,27,2527,0.059669031,1.547241495,0.980714035,2.508337787,0.142854584,DB1386710022000_,1.945928061,0.436473665,NA,10022000,Influenza,10021881,Infections and infestations,Infec,fluticasone,DB13867
,92881,DB13867,10037660,107,4443,69,2485,0.381803327,0.86735385,0.632226835,1.196489166,0.551932209,DB1386710037660_,0.59433005,-0.142308254,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,92892,DB13867,10043071,41,4509,22,2532,0.896037026,1.046509351,0.607402192,1.849135147,0.956301489,DB1386710043071_,0.044682051,0.045460198,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,fluticasone,DB13867
,92894,DB13867,10047700,169,4381,59,2495,0.001208272,1.631187897,1.2006986,2.242382962,0.006439462,DB1386710047700_,5.045310339,0.48930852,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,fluticasone,DB13867
,92899,DB13867,10047924,36,4514,19,2535,0.888527685,1.064054135,0.59292847,1.968210205,0.953826126,DB1386710047924_,0.047273882,0.062086268,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,92929,DB00722,10018985,29,25374,74,25958,1.68722764810527e-05,0.400890865,0.251444527,0.623900467,0.000171916,DB0072210018985_,8.668502061,-0.914066047,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,92931,DB08816,10018985,23,1128,39,1863,1,0.974025073,0.552286963,1.681879159,1,DB0881610018985_,0,-0.026318233,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,ticagrelor,DB08816
,92933,DB08816,10019211,23,1128,31,1871,0.480108043,1.230539394,0.681494577,2.192218247,0.644946741,DB0881610019211_,0.438587538,0.207452605,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ticagrelor,DB08816
,92945,DB08816,10047700,33,1118,30,1872,0.01781757,1.841396544,1.082253939,3.144305747,0.056422484,DB0881610047700_,2.874887541,0.610524275,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ticagrelor,DB08816
,92948,DB00722,10008111,36,25367,77,25955,0.000210246,0.478378591,0.31263885,0.7197681,0.001502535,DB0072210008111_,6.500601362,-0.737352829,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,92960,DB01409,10021097,96,5935,88,3878,0.027146311,0.712853784,0.526615571,0.965909503,0.078329302,DB0140910021097_,2.546833523,-0.338478951,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,tiotropium,DB01409
,92965,DB06228,10027091,31,15881,27,16049,0.601000558,1.160287604,0.66980247,2.021570819,0.745334479,DB0622810027091_,0.293922197,0.148667909,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,92968,DB00641,10055798,66,14058,72,12403,0.231408166,0.808759712,0.569660485,1.146586734,0.387636735,DB0064110055798_,0.947686627,-0.212253425,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,simvastatin,DB00641
,92971,DB00169,10064355,173,38518,88,18087,0.549621856,0.923140575,0.709684648,1.207992307,0.703966986,DB0016910064355_,0.351023818,-0.079973753,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,92975,DB01409,10064355,37,5994,29,3937,0.528308662,0.838036476,0.500632143,1.415373632,0.685757688,DB0140910064355_,0.377230938,-0.176693652,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,tiotropium,DB01409
,92987,DB08877,10042128,36,3253,28,3201,0.380682964,1.265113588,0.748693983,2.157934129,0.550726906,DB0887710042128_,0.596516226,0.235161911,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,ruxolitinib,DB08877
,93000,DB00904,10005802,47,23022,19,14437,0.128123635,1.551218917,0.892681834,2.800056029,0.253013016,DB0090410005802_,1.374314346,0.43904102,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,ondansetron,DB00904
,93001,DB01076,10005802,38,25709,36,25547,0.907528896,1.048919539,0.646995403,1.70346266,0.958758748,DB0107610005802_,0.042115802,0.047760624,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,93004,DB00544,10008531,35,2400,44,2609,0.571096546,0.864750494,0.536512174,1.38451456,0.721453007,DB0054410008531_,0.326488035,-0.14531426,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,fluorouracil,DB00544
,93005,DB00650,10008531,33,2098,37,1977,0.546833715,0.840489579,0.507189208,1.387510016,0.701521425,DB0065010008531_,0.354503838,-0.173770725,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,leucovorin,DB00650
,93007,DB01076,10008531,174,25573,172,25411,1,1.005219547,0.80890159,1.249280523,1,DB0107610008531_,0,0.005205973,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,93012,DB00222,10047942,43,3163,40,3088,0.912100384,1.049518261,0.66425309,1.661575247,0.960588545,DB0022210047942_,0.040209114,0.04833126,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,glimepiride,DB00222
,93029,DB01190,10046735,166,4768,38,2247,3.27800778524775e-05,2.058513487,1.433906291,3.022132167,0.000306704,DB0119010046735_,8.089626539,0.721984114,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,clindamycin,DB01190
,93031,DB00231,10037087,68,3228,22,2117,0.00318953,2.026846577,1.232928643,3.454679603,0.01422409,DB0023110037087_,4.25281829,0.706481175,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,temazepam,DB00231
,93042,DB05259,10037844,207,11063,70,2658,0.017332189,0.710503801,0.537464519,0.94874785,0.055244842,DB0525910037844_,2.895980293,-0.341780982,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,glatiramer,DB05259
,93046,DB09020,10007559,34,1920,27,1577,1,1.034293288,0.602812377,1.790773274,1,DB0902010007559_,0,0.03371838,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,bisacodyl,DB09020
,93048,DB00169,10007617,32,38659,43,18132,8.70519903874068e-06,0.349047978,0.213683849,0.564827862,9.61816547849091e-05,DB0016910007617_,9.249271917,-1.052545894,male,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,93049,DB00480,10007617,35,67393,52,67610,0.085629118,0.675249502,0.426840133,1.05666399,0.187743368,DB0048010007617_,1.672679311,-0.392673023,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,93050,DB00512,10007617,32,4705,34,5064,1,1.012990149,0.604113421,1.694968457,1,DB0051210007617_,0,0.012906501,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,vancomycin,DB00512
,93056,DB00524,10009033,37,1540,36,1308,0.634639072,0.872985716,0.533208817,1.430543752,0.772844497,DB0052410009033_,0.257677419,-0.135836086,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metolazone,DB00524
,93061,DB09020,10035664,93,1861,98,1506,0.085385988,0.768017663,0.567160623,1.039413137,0.187362742,DB0902010035664_,1.674708743,-0.263942547,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,bisacodyl,DB09020
,93062,DB00046,10037377,33,5426,23,4669,0.50231312,1.234584567,0.702220933,2.205507083,0.663599144,DB0004610037377_,0.41007701,0.21073453,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin lispro,DB00046
,93064,DB00471,10037377,77,14112,49,5416,0.006905247,0.603110851,0.41553026,0.882652031,0.026515882,DB0047110037377_,3.630011417,-0.505654267,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,93065,DB00512,10037377,23,4714,30,5068,0.494990734,0.824256907,0.456514894,1.46994189,0.657394914,DB0051210037377_,0.419470355,-0.193273017,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vancomycin,DB00512
,93068,DB01409,10037377,32,5999,31,3935,0.123101879,0.677147041,0.399408694,1.149384753,0.245834847,DB0140910037377_,1.403095321,-0.389866834,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,93072,DB14726,10033425,37,1980,25,2823,0.00409784,2.109817055,1.232033574,3.66906877,0.017420624,DB1472610033425_,4.050100472,0.74660124,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,dabigatran,DB14726
,93073,DB14726,10048959,31,1986,34,2814,0.312948292,1.291813191,0.765015437,2.174120186,0.480465769,DB1472610048959_,0.732999293,0.256046806,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,dabigatran,DB14726
,93082,DB01261,10003445,18,3763,33,3270,0.010833969,0.474038746,0.250787876,0.868583241,0.037959326,DB0126110003445_,3.271240049,-0.746466217,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,sitagliptin,DB01261
,93092,DB00678,10001760,246,15353,32,10692,5.22525747194351e-27,5.353394289,3.690892238,8.007311649,9.28012788175913e-25,DB0067810001760_,55.336752,1.677730806,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,93095,DB00588,10013950,114,16410,37,8431,0.015484368,1.582946415,1.082724245,2.362445336,0.050528445,DB0058810013950_,2.985218842,0.45928793,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,93100,DB00588,10074170,48,16476,25,8443,1,0.983882013,0.594241179,1.666457618,1,DB0058810074170_,0,-0.016249295,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,93103,DB01611,10020772,141,11772,19,2342,0.133152361,1.476353528,0.908845648,2.530558118,0.260138977,DB0161110020772_,1.346539264,0.389575215,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,hydroxychloroquine,DB01611
,93108,DB00451,10030973,59,47212,14,15405,0.341295136,1.375071334,0.758234019,2.66790833,0.510452226,DB0045110030973_,0.672458228,0.318505609,NA,10030973,Oral discomfort,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,93130,DB09053,10003239,74,2211,90,3962,0.016697314,1.473221888,1.0633939,2.035884399,0.053627675,DB0905310003239_,2.925690018,0.387451763,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ibrutinib,DB09053
,93133,DB01592,10020937,87,6189,21,3046,0.002633572,2.038827863,1.251703227,3.465498168,0.012157262,DB0159210020937_,4.409828559,0.712375066,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,iron,DB01592
,93134,DB01592,10035528,58,6218,40,3027,0.104305674,0.705885415,0.462622237,1.086675288,0.217470442,DB0159210035528_,1.525692335,-0.348302356,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,iron,DB01592
,93136,DB06228,10040829,43,15869,28,16048,0.074814475,1.553006591,0.942385673,2.597364923,0.169533038,DB0622810040829_,1.774707458,0.440192788,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,rivaroxaban,DB06228
,93137,DB00706,10048959,15,1060,270,15655,0.539518222,0.820492153,0.451209371,1.384164769,0.695329075,DB0070610048959_,0.363370057,-0.197850933,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,93147,DB00264,10005395,48,29559,24,24868,0.043477574,1.682580786,1.010234934,2.872843586,0.112589759,DB0026410005395_,2.18400452,0.520328797,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,metoprolol,DB00264
,93151,DB06643,10005395,208,52213,55,7460,0.000117852,0.540347664,0.399264799,0.741981323,0.00091826,DB0664310005395_,6.993029442,-0.615542524,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,denosumab,DB06643
,93162,DB00451,10033295,206,47065,86,15333,0.056513241,0.780368487,0.603484203,1.016418248,0.136989952,DB0045110033295_,1.9878477,-0.247989052,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,93165,DB00564,10012735,61,2543,29,1434,0.50588385,1.186123178,0.746535756,1.923937937,0.666707964,DB0056410012735_,0.405403164,0.170690155,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,carbamazepine,DB00564
,93202,DB01377,10017955,59,3737,38,2632,0.75544724,1.093537852,0.712899093,1.695292894,0.862800874,DB0137710017955_,0.147571352,0.089418176,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,magnesium oxide,DB01377
,93203,DB09140,10017955,61,3680,26,1772,0.64598289,1.129693212,0.700257647,1.869804395,0.781607075,DB0914010017955_,0.246403126,0.121946102,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,oxygen,DB09140
,93205,DB00836,10021015,61,5474,17,4058,0.000190122,2.659763604,1.530684113,4.865548221,0.001380483,DB0083610021015_,6.585321564,0.978237248,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,loperamide,DB00836
,93207,DB09140,10021015,41,3700,15,1783,0.393234779,1.317152604,0.711498948,2.568891098,0.563156597,DB0914010021015_,0.574197543,0.275472288,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,oxygen,DB09140
,93216,DB00734,10019211,69,3981,42,4860,0.000353843,2.005416528,1.343828187,3.024624829,0.002313912,DB0073410019211_,6.068815852,0.695851784,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,93220,DB00497,10003997,26,19241,30,16345,0.283675353,0.736234666,0.418051797,1.288522409,0.448060972,DB0049710003997_,0.802825958,-0.306206371,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,oxycodone,DB00497
,93221,DB00904,10003997,44,23025,55,14401,0.000606832,0.500359895,0.328581462,0.758027395,0.003633347,DB0090410003997_,5.617600928,-0.692427649,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,ondansetron,DB00904
,93270,DB00273,10027417,78,8403,16,2177,0.443670701,1.262956941,0.729250769,2.322647641,0.611743257,DB0027310027417_,0.491442599,0.23345575,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,topiramate,DB00273
,93281,DB00864,10001551,19,6850,47,8345,0.008819801,0.492512605,0.272688521,0.856357354,0.032193926,DB0086410001551_,3.435977493,-0.708235226,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,tacrolimus,DB00864
,93282,DB00688,10003481,19,6471,32,5346,0.015814015,0.490560193,0.262387884,0.893327388,0.051384065,DB0068810003481_,2.968427177,-0.712207291,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,mycophenolate mofetil,DB00688
,93283,DB00864,10003481,16,6853,42,8350,0.007861535,0.464199914,0.243422126,0.844004043,0.029364851,DB0086410003481_,3.527956854,-0.76743997,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,tacrolimus,DB00864
,93284,DB00688,10069326,33,6457,17,5361,0.118331956,1.61161806,0.87114689,3.08863572,0.23870725,DB0068810069326_,1.432517374,0.47723868,NA,10069326,Product substitution issue,10077536,Product issues,Prod,mycophenolate mofetil,DB00688
,93285,DB00864,10069326,37,6832,29,8363,0.082225263,1.56170654,0.933541647,2.635967218,0.182030496,DB0086410069326_,1.703581045,0.445779159,NA,10069326,Product substitution issue,10077536,Product issues,Prod,tacrolimus,DB00864
,93292,DB00051,10040829,75,25656,40,11380,0.362600523,0.831699439,0.558941006,1.254001736,0.53220767,DB0005110040829_,0.630721509,-0.184284155,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,93296,DB00620,10040829,31,4797,21,3111,0.887475423,0.957386685,0.531707137,1.756302999,0.953356575,DB0062010040829_,0.047766285,-0.04354791,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,triamcinolone,DB00620
,93312,DB00051,10058080,81,25650,70,11350,6.03007931970339e-05,0.512019297,0.366988168,0.715989755,0.000518061,DB0005110058080_,7.56541837,-0.669392964,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,adalimumab,DB00051
,93316,DB00620,10058080,35,4793,18,3114,0.481807356,1.263251594,0.694902471,2.373752745,0.646303109,DB0062010058080_,0.436486676,0.233689027,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,triamcinolone,DB00620
,93317,DB00999,10058080,41,21389,16,12223,0.216393329,1.464355347,0.803703397,2.796654788,0.369116366,DB0099910058080_,0.99664333,0.38141511,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,93319,DB00051,10067268,31,25700,21,11399,0.134600115,0.654758874,0.3642138,1.199437031,0.262090823,DB0005110067268_,1.339064184,-0.423488243,NA,10067268,Post procedural infection,10021881,Infections and infestations,Infec,adalimumab,DB00051
,93326,DB01075,10022086,141,19807,33,11064,1.53173284235859e-06,2.386643708,1.622827592,3.603424047,2.0985977462286e-05,DB0107510022086_,10.77165608,0.869888073,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,93330,DB00581,10010264,60,2053,31,2038,0.002941908,1.921040257,1.219535211,3.080603269,0.013292315,DB0058110010264_,4.320569265,0.65286684,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,lactulose,DB00581
,93333,DB00203,10028810,488,13390,152,8786,6.03474164039815e-17,2.106550047,1.74874187,2.549171792,4.59111965319437e-15,DB0020310028810_,33.01465247,0.745051561,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,sildenafil,DB00203
,93334,DB00203,10040753,210,13668,66,8872,7.75607733577387e-08,2.065274706,1.557079125,2.770345742,1.4387331882203e-06,DB0020310040753_,13.45174756,0.725263247,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,sildenafil,DB00203
,93338,DB00203,10062244,84,13794,30,8908,0.005069475,1.808159499,1.177806807,2.845146681,0.020687961,DB0020310062244_,3.878203361,0.592309477,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,93343,DB00186,10040979,30,16871,21,9987,0.564199039,0.845672693,0.468007543,1.555026343,0.716026349,DB0018610040979_,0.334038313,-0.167622881,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,93358,DB01050,10053425,91,18017,18,9353,6.38511629494681e-05,2.624362433,1.569737303,4.627662548,0.000542885,DB0105010053425_,7.518613738,0.964837984,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,93359,DB01076,10053425,77,25670,32,25551,1.91976526574951e-05,2.395198868,1.566187068,3.740799912,0.000192636,DB0107610053425_,8.554707569,0.873466262,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,93365,DB00484,10013700,69,2438,26,1754,0.004379186,1.909010349,1.194417399,3.136758928,0.018373009,DB0048410013700_,3.99687257,0.646584966,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,brimonidine,DB00484
,93366,DB00112,10071066,52,5881,22,4069,0.057305644,1.63529561,0.974108959,2.832265524,0.138390873,DB0011210071066_,1.977673182,0.491823589,NA,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,bevacizumab,DB00112
,93367,DB00321,10033775,98,7349,28,2822,0.192700167,1.343923072,0.873120703,2.13014287,0.340021071,DB0032110033775_,1.078747691,0.295593002,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,93368,DB00476,10033775,1548,15709,504,5673,0.055506502,1.109179024,0.997787498,1.234467329,0.135179136,DB0047610033775_,2.001154448,0.103620124,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,93371,DB00186,10040070,80,16821,56,9952,0.329723489,0.845213997,0.592672751,1.212574825,0.498377339,DB0018610040070_,0.696397781,-0.168165433,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,lorazepam,DB00186
,93379,DB00836,10040070,34,5501,27,4048,0.795739802,0.926654189,0.541747492,1.599595447,0.889397596,DB0083610040070_,0.117210904,-0.076174826,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,loperamide,DB00836
,93380,DB01050,10040070,35,18073,25,9346,0.221702709,0.723954416,0.42083904,1.262727465,0.375625609,DB0105010040070_,0.979162352,-0.32302685,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,93381,DB01075,10040070,33,19915,22,11075,0.573501403,0.834184605,0.471719206,1.502625272,0.72334378,DB0107510040070_,0.323870679,-0.181300552,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,93383,DB06724,10040070,44,7885,18,3901,0.588698252,1.209314282,0.683559838,2.226785969,0.735582809,DB0672410040070_,0.307092157,0.19005349,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,93385,DB00795,10037844,257,4312,52,1451,0.000696651,1.663027379,1.222216255,2.299555919,0.004075558,DB0079510037844_,5.502747544,0.508639664,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sulfasalazine,DB00795
,93388,DB00635,10040829,101,32952,54,23740,0.086622122,1.347485183,0.958578119,1.91235629,0.189422835,DB0063510040829_,1.663773543,0.298240028,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,93390,DB01076,10040829,99,25648,62,25521,0.004373926,1.588844256,1.144608368,2.220137235,0.018355334,DB0107610040829_,3.997835085,0.463006869,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,93397,DB05351,10010774,42,2681,25,1106,0.175075754,0.693125295,0.410467197,1.19289339,0.317567194,DB0535110010774_,1.147065849,-0.366544496,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,dexlansoprazole,DB05351
,93398,DB00126,10013990,35,10136,17,5928,0.568042164,1.204122825,0.656051548,2.294075642,0.719063222,DB0012610013990_,0.329805995,0.185751356,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,ascorbic acid,DB00126
,93401,DB01373,10013990,43,22677,23,7358,0.061595508,0.60662893,0.357262733,1.055303702,0.146373559,DB0137310013990_,1.921593304,-0.499837993,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,calcium,DB01373
,93404,DB00126,10016766,72,10099,40,5905,0.844569572,1.052481314,0.704407073,1.592461581,0.921485667,DB0012610016766_,0.081768056,0.051150532,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,93406,DB00451,10016766,209,47062,71,15348,0.78089013,0.959993671,0.729604459,1.275861397,0.880700697,DB0045110016766_,0.127037442,-0.040828588,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,93409,DB05351,10019211,164,2559,39,1092,0.000855859,1.794209611,1.248688541,2.633049099,0.00484259,DB0535110019211_,5.330305607,0.584564597,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,dexlansoprazole,DB05351
,93411,DB00203,10058080,80,13798,36,8902,0.08563804,1.433679954,0.955055596,2.189924148,0.18774727,DB0020310058080_,1.67265853,0.360244533,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,93412,DB00203,10062237,51,13827,29,8909,0.647111686,1.133135637,0.704096846,1.855467599,0.782343935,DB0020310062237_,0.245460821,0.12498869,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,sildenafil,DB00203
,93415,DB00559,10015150,58,9601,18,3288,0.792655481,1.103487017,0.639853056,1.993161432,0.88758728,DB0055910015150_,0.119248419,0.098475181,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,bosentan,DB00559
,93416,DB01240,10015150,191,5560,54,1522,0.812866326,0.96823415,0.708226605,1.342498996,0.899401893,DB0124010015150_,0.1060253,-0.03228133,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,epoprostenol,DB01240
,93417,DB00559,10022004,43,9616,7,3299,0.072600624,2.107465726,0.938672433,5.557563501,0.165840195,DB0055910022004_,1.796730635,0.745486148,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,93418,DB00820,10022004,99,11816,46,5770,0.859087756,1.050948156,0.732489632,1.527525682,0.933162041,DB0082010022004_,0.069176415,0.049692763,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,93419,DB01240,10022004,55,5696,20,1556,0.26136746,0.751260867,0.441537623,1.327582321,0.42291506,DB0124010022004_,0.860583925,-0.286002328,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,93425,DB00374,10000087,432,17284,95,5629,0.000473675,1.480909677,1.180861512,1.873267517,0.002952818,DB0037410000087_,5.824995348,0.392656546,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,93426,DB00559,10000087,132,9527,30,3276,0.045486557,1.512910539,1.009260424,2.335370579,0.116490719,DB0055910000087_,2.149943674,0.414035305,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,93427,DB00374,10016766,107,17609,39,5685,0.500116541,0.885747475,0.607798245,1.314707595,0.661728287,DB0037410016766_,0.41290025,-0.121323386,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,93429,DB00820,10016766,82,11833,28,5788,0.103910293,1.432455803,0.921430665,2.2883098,0.216888911,DB0082010016766_,1.528369985,0.359390316,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,93432,DB08880,10002855,44,3294,8,801,0.596760848,1.337340555,0.619543215,3.302259115,0.742104315,DB0888010002855_,0.29826546,0.290682981,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,teriflunomide,DB08880
,93434,DB08880,10016173,189,3149,51,758,0.50184891,0.892055224,0.644397799,1.253379751,0.663252563,DB0888010016173_,0.410599421,-0.114227238,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,teriflunomide,DB08880
,93435,DB08893,10016173,110,1975,60,998,0.676622042,0.926437735,0.663787382,1.303331557,0.803963008,DB0889310016173_,0.218202021,-0.07640844,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,mirabegron,DB08893
,93437,DB08880,10022437,64,3274,15,794,1,1.034739724,0.579255502,1.96592729,1,DB0888010022437_,0,0.03414992,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,teriflunomide,DB08880
,93438,DB08893,10022437,39,2046,22,1036,0.683294737,0.897662297,0.516103306,1.598468278,0.808535448,DB0889310022437_,0.212530757,-0.107961342,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,mirabegron,DB08893
,93440,DB08880,10028372,81,3257,21,788,0.800145705,0.933204789,0.567559463,1.598554458,0.891935108,DB0888010028372_,0.114361898,-0.069130607,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,teriflunomide,DB08880
,93464,DB01611,10010305,52,11861,8,2353,0.603368361,1.289455617,0.607229077,3.147227451,0.747034261,DB0161110010305_,0.29164423,0.254220127,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,hydroxychloroquine,DB01611
,93468,DB00213,10015916,34,18861,17,13404,0.257593186,1.421329461,0.771963303,2.714055873,0.418443663,DB0021310015916_,0.871213015,0.351592674,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,pantoprazole,DB00213
,93473,DB01373,10015916,60,22660,9,7372,0.024783156,2.168693671,1.068910828,4.974257462,0.073021493,DB0137310015916_,2.617001457,0.774124991,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,calcium,DB01373
,93515,DB00169,10028997,76,38615,38,18137,0.76334828,0.939378012,0.628094727,1.426158269,0.868992812,DB0016910028997_,0.140420425,-0.062537312,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cholecalciferol,DB00169
,93517,DB00213,10028997,31,18864,24,13397,0.784971986,0.917330294,0.520838602,1.634197836,0.883280407,DB0021310028997_,0.124112568,-0.086287682,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pantoprazole,DB00213
,93523,DB00996,10028997,61,38892,35,22390,1,1.003357246,0.651410198,1.567398021,1,DB0099610028997_,0,0.003351623,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,gabapentin,DB00996
,93524,DB00999,10028997,43,21387,27,12212,0.710090762,0.909376567,0.548941852,1.531246182,0.827117597,DB0099910028997_,0.189808397,-0.094996005,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,hydrochlorothiazide,DB00999
,93525,DB01373,10028997,41,22679,9,7372,0.326873724,1.480772638,0.708504122,3.466916063,0.495294624,DB0137310028997_,0.702602493,0.392564004,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,calcium,DB01373
,93562,DB00091,10047571,79,5431,14,2656,0.000137577,2.759329254,1.547697928,5.285731655,0.001047268,DB0009110047571_,6.861570453,1.014987626,female,10047571,Visual impairment,10015919,Eye disorders,Eye,cyclosporine,DB00091
,93564,DB00213,10047571,122,18773,32,13389,6.41262659443672e-08,2.718991148,1.828171198,4.151680936,1.2109170146923e-06,DB0021310047571_,13.62413262,1.00026091,female,10047571,Visual impairment,10015919,Eye disorders,Eye,pantoprazole,DB00213
,93565,DB00635,10047571,228,32825,84,23710,5.03301960908733e-08,1.960536285,1.519311007,2.550336626,9.73457839770865e-07,DB0063510047571_,13.84241132,0.673218051,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,prednisone,DB00635
,93569,DB01611,10047571,78,11835,13,2348,0.671317361,1.190353294,0.655779511,2.338800832,0.800574751,DB0161110047571_,0.22242537,0.174250149,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,hydroxychloroquine,DB01611
,93573,DB00169,10061520,64,38627,23,18152,0.301378459,1.307576737,0.800458503,2.207809789,0.46764856,DB0016910061520_,0.760038205,0.268175605,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,93575,DB00213,10061520,43,18852,10,13411,0.000675052,3.058816226,1.512922746,6.829568226,0.003974407,DB0021310061520_,5.527879742,1.118027987,female,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,93576,DB00588,10061520,62,16462,19,8449,0.059099945,1.674759886,0.987459084,2.967937102,0.141808576,DB0058810061520_,1.953277184,0.515669804,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,93582,DB00996,10061520,69,38884,24,22401,0.031307484,1.656268599,1.027276239,2.757327325,0.087586315,DB0099610061520_,2.435130516,0.50456724,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,93583,DB00999,10061520,44,21386,9,12230,0.002536886,2.795725052,1.346380859,6.515449252,0.011794785,DB0099910061520_,4.440097815,1.028091483,female,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,93590,DB00526,10013968,87,1511,88,1806,0.311576534,1.181592975,0.861206597,1.620981295,0.479025691,DB0052610013968_,0.736001048,0.166863507,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxaliplatin,DB00526
,93591,DB00112,10016173,67,5866,66,4025,0.040997012,0.696593944,0.487133603,0.996323185,0.107652994,DB0011210016173_,2.228842241,-0.361552615,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,bevacizumab,DB00112
,93593,DB00863,10016173,322,10351,139,5701,0.017685876,1.275882097,1.039645544,1.572313043,0.056103457,DB0086310016173_,2.880557852,0.24363778,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,93603,DB01255,10003549,36,2097,17,1561,0.126302474,1.576182772,0.859005506,3.004173541,0.250513908,DB0125510003549_,1.38424084,0.455005957,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,lisdexamfetamine,DB01255
,93604,DB08875,10003549,22,621,52,1191,0.455053977,0.811525627,0.464784613,1.374521236,0.622616927,DB0887510003549_,0.473823834,-0.208839313,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,cabozantinib,DB08875
,93605,DB00213,10013952,77,18818,37,13384,0.056486375,1.480116729,0.987013857,2.255496429,0.136931142,DB0021310013952_,1.988277091,0.392120956,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,93609,DB00213,10035669,38,18857,53,13368,0.001840292,0.508280839,0.325812973,0.786179297,0.009086518,DB0021310035669_,4.700963537,-0.676721151,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,93610,DB00295,10035669,34,14629,43,9559,0.004770113,0.516667675,0.319298244,0.83006983,0.019698731,DB0029510035669_,3.927201082,-0.660355405,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,morphine,DB00295
,93611,DB00425,10035669,40,12655,11,7473,0.020443946,2.147261238,1.08045509,4.643481508,0.062875929,DB0042510035669_,2.766591874,0.764193188,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,zolpidem,DB00425
,93625,DB00338,10003504,34,33640,18,22254,0.481418718,1.249544887,0.685980786,2.350575338,0.646045387,DB0033810003504_,0.436885519,0.222779395,NA,10003504,Aspiration,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,93628,DB00338,10008589,36,33638,19,22253,0.491666953,1.253432796,0.699965845,2.314053146,0.654764485,DB0033810008589_,0.423479674,0.225886024,NA,10008589,Choking,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,93630,DB00761,10007515,105,15202,85,8540,0.014978382,0.693987933,0.515713563,0.936088109,0.049252815,DB0076110007515_,3.010788764,-0.365300706,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,93631,DB01202,10007515,85,6629,64,5654,0.508434068,1.132760348,0.807674769,1.595488059,0.668962056,DB0120210007515_,0.402027937,0.12465744,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,levetiracetam,DB01202
,93638,DB01592,10015150,57,6219,22,3045,0.40009916,1.268508529,0.761766648,2.183553075,0.569981289,DB0159210015150_,0.562151745,0.237841824,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,iron,DB01592
,93648,DB06403,10010305,104,21367,24,6637,0.211437174,1.345989687,0.856183643,2.19658749,0.363089283,DB0640310010305_,1.013106516,0.297129569,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ambrisentan,DB06403
,93650,DB06403,10024670,51,21420,25,6636,0.077566999,0.632011901,0.384071159,1.065391492,0.174238222,DB0640310024670_,1.747331822,-0.458847054,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,ambrisentan,DB06403
,93661,DB00404,10013952,72,19820,26,9836,0.196758783,1.374280671,0.86610932,2.244152233,0.345086048,DB0040410013952_,1.063961479,0.317930446,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,93662,DB01076,10013952,84,25663,75,25508,0.525618818,1.113232518,0.805198051,1.541593551,0.683571429,DB0107610013952_,0.380424124,0.107267961,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,93669,DB00924,10042674,93,10069,22,4229,0.013569173,1.775400837,1.104434211,2.972897849,0.045397531,DB0092410042674_,3.092297549,0.574026221,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,93671,DB01097,10042674,74,6191,8,1495,0.024336459,2.233462662,1.073306303,5.376687354,0.072036467,DB0109710042674_,2.630582798,0.803553144,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,93677,DB00254,10003553,49,5886,7,3381,0.000118686,4.020441901,1.808726761,10.53567876,0.000922703,DB0025410003553_,6.988202645,1.391391822,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxycycline,DB00254
,93680,DB01015,10003553,42,9845,15,9366,0.000769413,2.66343379,1.445966084,5.173939128,0.004426358,DB0101510003553_,5.420178233,0.979616189,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,93682,DB01050,10003553,101,18007,25,9346,0.000631962,2.09679198,1.341451044,3.39412168,0.00376243,DB0105010003553_,5.582690275,0.740408548,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,93687,DB00043,10008469,170,6243,55,2245,0.540270063,1.111484547,0.812189572,1.541224761,0.695871547,DB0004310008469_,0.362590194,0.105696551,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,93688,DB00254,10008469,52,5883,17,3371,0.044506446,1.752629809,0.995292161,3.238466904,0.114601483,DB0025410008469_,2.166294534,0.561117408,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,93691,DB01015,10008469,54,9833,28,9353,0.01045343,1.834362937,1.1405238,3.010184906,0.036866818,DB0101510008469_,3.300443362,0.606697248,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,93697,DB14512,10008469,91,4753,25,2387,0.007059229,1.827905354,1.159766257,2.979118462,0.026967783,DB1451210008469_,3.613112343,0.603170696,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,93698,DB00043,10011224,198,6215,73,2227,0.833816244,0.971901657,0.736058698,1.295009551,0.913682907,DB0004310011224_,0.090271697,-0.028500656,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omalizumab,DB00043
,93700,DB00482,10011224,119,8140,50,3021,0.48549921,0.883311023,0.62792438,1.258393737,0.649548099,DB0048210011224_,0.43147839,-0.124077906,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,celecoxib,DB00482
,93703,DB01611,10011224,268,11645,40,2321,0.10300277,1.33536974,0.952029173,1.917198749,0.215490911,DB0161110011224_,1.534836547,0.289208212,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxychloroquine,DB01611
,93705,DB00279,10019211,79,1158,6,210,0.03983354,2.38668921,1.03008033,6.788069626,0.105350366,DB0027910019211_,2.250463667,0.869907138,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,liothyronine,DB00279
,93709,DB00254,10025482,143,5792,52,3336,0.004197648,1.583835299,1.141957202,2.226038271,0.017759292,DB0025410025482_,4.0308464,0.45984931,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,93711,DB00620,10025482,155,4673,44,3088,2.07532460301876e-07,2.327646227,1.650119729,3.34254999,3.50803261674264e-06,DB0062010025482_,12.56045519,0.844857554,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,93716,DB04861,10025482,65,1900,31,1356,0.073809837,1.496260333,0.955198957,2.389106827,0.16788859,DB0486110025482_,1.784454675,0.402968884,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,nebivolol,DB04861
,93717,DB05351,10025482,77,2646,17,1114,0.015600564,1.90666435,1.110849964,3.456314318,0.050838188,DB0535110025482_,2.979107479,0.645355302,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,dexlansoprazole,DB05351
,93718,DB00043,10028810,39,6374,25,2275,0.03150005,0.556849169,0.327769937,0.962344505,0.088017308,DB0004310028810_,2.430221807,-0.585460868,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,omalizumab,DB00043
,93720,DB00482,10028810,127,8132,32,3039,0.047973153,1.483046213,0.997264711,2.264724983,0.121294182,DB0048210028810_,2.10953643,0.394098224,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,celecoxib,DB00482
,93721,DB00620,10028810,52,4776,34,3098,1,0.992067907,0.630083215,1.5804664,1,DB0062010028810_,0,-0.00796372,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,triamcinolone,DB00620
,93724,DB01409,10028810,109,5922,45,3921,0.007756908,1.603697746,1.120459357,2.328682448,0.029056624,DB0140910028810_,3.538508817,0.472312054,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,tiotropium,DB01409
,93726,DB01611,10028810,200,11713,33,2328,0.373799922,1.204551225,0.827848007,1.802873333,0.543586774,DB0161110028810_,0.609565927,0.18610707,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,hydroxychloroquine,DB01611
,93728,DB04861,10028810,35,1930,15,1372,0.112166636,1.658481542,0.878519794,3.282108134,0.229314771,DB0486110028810_,1.472659672,0.50590245,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,nebivolol,DB04861
,93729,DB05351,10028810,36,2687,14,1117,1,1.068937441,0.560027348,2.154350613,1,DB0535110028810_,0,0.066665109,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,dexlansoprazole,DB05351
,93730,DB14512,10028810,92,4752,46,2366,1,0.995791249,0.689020012,1.456482054,1,DB1451210028810_,0,-0.004217633,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,mometasone furoate,DB14512
,93731,DB00043,10039101,38,6375,16,2284,0.64210558,0.8509412,0.46220708,1.637994035,0.778632739,DB0004310039101_,0.250215796,-0.161412248,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omalizumab,DB00043
,93736,DB01015,10039101,49,9838,31,9350,0.092141858,1.502201924,0.938036203,2.439348148,0.198650652,DB0101510039101_,1.616207515,0.406931981,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,93739,DB01611,10039101,83,11830,12,2349,0.404574345,1.37336387,0.744283525,2.769519994,0.574357907,DB0161110039101_,0.554502545,0.31726311,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxychloroquine,DB01611
,93743,DB14512,10039101,37,4807,15,2397,0.556943815,1.229932774,0.657395226,2.417327092,0.710195904,DB1451210039101_,0.342214425,0.206959513,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mometasone furoate,DB14512
,93744,DB00043,10040753,97,6316,28,2272,0.357643177,1.24613557,0.80860895,1.977055773,0.52735616,DB0004310040753_,0.639879133,0.220047218,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,omalizumab,DB00043
,93745,DB00254,10040753,141,5794,32,3356,3.58196720676464e-07,2.551964412,1.723948949,3.882385,5.72875010829379e-06,DB0025410040753_,12.07001318,0.93686342,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,doxycycline,DB00254
,93747,DB00482,10040753,150,8109,35,3036,0.012093367,1.604561912,1.101456735,2.395343254,0.041389864,DB0048210040753_,3.184719269,0.472850767,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,celecoxib,DB00482
,93748,DB00768,10040753,66,1849,15,669,0.123601804,1.591795568,0.891284056,3.024393455,0.246539243,DB0076810040753_,1.400234095,0.464862667,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,olopatadine,DB00768
,93749,DB01015,10040753,147,9740,73,9308,3.41361424409864e-06,1.924312058,1.44160275,2.587770674,4.22641782412306e-05,DB0101510040753_,10.07157068,0.654568532,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,93751,DB01409,10040753,149,5882,28,3938,5.39221652144988e-12,3.562302934,2.361751702,5.554571629,2.16058553759619e-10,DB0140910040753_,22.25547166,1.270407227,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,tiotropium,DB01409
,93755,DB05351,10040753,56,2667,7,1124,0.000723518,3.37049533,1.52632978,8.794268583,0.004208743,DB0535110040753_,5.470591329,1.215059716,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,dexlansoprazole,DB05351
,93756,DB14512,10040753,190,4654,55,2357,0.000188034,1.749418441,1.283832713,2.416894706,0.001369105,DB1451210040753_,6.593597822,0.559283414,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,mometasone furoate,DB14512
,93760,DB00588,10043521,79,16445,21,8447,0.005754919,1.932262476,1.181046944,3.294997677,0.022904423,DB0058810043521_,3.776425246,0.658691584,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,93774,DB00451,10052137,45,47226,7,15412,0.074981521,2.097792208,0.938878136,5.515628456,0.169806853,DB0045110052137_,1.773093647,0.740885462,NA,10052137,Ear discomfort,10013993,Ear and labyrinth disorders,Ear,levothyroxine,DB00451
,93791,DB00451,10070488,48,47223,10,15409,0.223809832,1.566200013,0.782205228,3.47277877,0.378293449,DB0045110070488_,0.972085065,0.448652312,NA,10070488,Upper-airway cough syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,93808,DB00060,10028810,80,9428,19,2446,0.803690302,1.09236784,0.654582903,1.912104104,0.893803439,DB0006010028810_,0.112269395,0.08834767,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,interferon beta-1a,DB00060
,93811,DB00678,10028334,299,15300,111,10613,8.33031344673265e-09,1.86845867,1.495535919,2.34812813,1.90687038666762e-07,DB0067810028334_,15.47263229,0.62511385,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,93812,DB14500,10028334,183,7626,86,3987,0.436256829,1.112507862,0.853815827,1.459057074,0.604816095,DB1450010028334_,0.502830842,0.106616802,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,93813,DB00678,10028411,195,15404,104,10620,0.038152042,1.292670776,1.012365166,1.658428452,0.101897722,DB0067810028411_,2.283785695,0.256710447,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,93814,DB14500,10028411,113,7696,33,4040,0.002726891,1.79746881,1.207660289,2.741083162,0.012505685,DB1450010028411_,4.381571923,0.586379459,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,93816,DB00795,10035664,63,4506,27,1476,0.267604106,0.764350375,0.477751342,1.253197306,0.429910089,DB0079510035664_,0.844179187,-0.268728989,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sulfasalazine,DB00795
,93833,DB01268,10000087,53,2090,64,3066,0.297169388,1.214793537,0.824147964,1.784193449,0.463058206,DB0126810000087_,0.769902517,0.194574134,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,93834,DB05812,10010774,8,174,112,7841,0.005370672,3.217954617,1.334961941,6.703382215,0.021656533,DB0581210010774_,3.832448109,1.168745945,female,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,abiraterone,DB05812
,93848,DB00783,10013710,106,16608,6,367,0.036150927,0.390428868,0.171949109,1.09493357,0.097844376,DB0078310013710_,2.324377067,-0.940509483,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,estradiol,DB00783
,93851,DB01036,10011906,52,1449,18,404,0.461752814,0.805555495,0.457424985,1.480330583,0.628950523,DB0103610011906_,0.463702685,-0.216223184,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tolterodine,DB01036
,93866,DB08868,10047340,127,9075,18,2493,0.005909932,1.938090206,1.175299746,3.382080529,0.023391443,DB0886810047340_,3.755384997,0.661703058,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,fingolimod,DB08868
,93883,DB08931,10016807,561,6016,203,2243,0.765904786,1.030381101,0.869388518,1.224702839,0.870960103,DB0893110016807_,0.13815911,0.029928735,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,riociguat,DB08931
,93904,DB00993,10047700,96,3153,38,1581,0.264361448,1.266749273,0.856949081,1.905685151,0.426303108,DB0099310047700_,0.852604666,0.236453992,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,azathioprine,DB00993
,93918,DB00451,10043528,86,47185,16,15403,0.037926056,1.75452034,1.020971506,3.207424282,0.101484922,DB0045110043528_,2.287845048,0.562195509,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,93922,DB00374,10060945,46,17670,7,5717,0.076316475,2.125957026,0.952687948,5.584646461,0.172002447,DB0037410060945_,1.760246577,0.754222066,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,93926,DB00722,10038776,45,25358,36,25996,0.316899808,1.281439824,0.808074728,2.045388039,0.484694158,DB0072210038776_,0.724237189,0.247984308,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,93953,DB00471,10003239,468,13721,99,5366,7.22468373343275e-09,1.848688624,1.481703759,2.32562215,1.67387229557761e-07,DB0047110003239_,15.60295597,0.614476536,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,93954,DB09140,10003239,131,3610,58,1740,0.635764073,1.088623626,0.788728191,1.518077245,0.773606401,DB0914010003239_,0.256692061,0.08491417,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,oxygen,DB09140
,93955,DB01202,10008479,46,6668,36,5682,0.739649062,1.088857695,0.687600711,1.736260436,0.850225247,DB0120210008479_,0.162253969,0.085129161,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,93956,DB01222,10008479,179,9095,98,5307,0.659893082,1.065796248,0.82648086,1.381109735,0.792289944,DB0122210008479_,0.232827864,0.063722171,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,93971,DB00471,10028411,166,14023,44,5421,0.024784525,1.458369265,1.038781947,2.085732731,0.073021493,DB0047110028411_,2.617001457,0.37731887,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,93972,DB00722,10028411,271,25132,206,25826,0.001258104,1.351847897,1.122695994,1.629738602,0.006643081,DB0072210028411_,5.014179431,0.301472469,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,93973,DB00924,10028411,153,10009,36,4215,0.001260334,1.789700734,1.235528029,2.654895104,0.006652855,DB0092410028411_,5.012709206,0.582048418,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,93974,DB01222,10028411,131,9143,46,5359,0.002781986,1.669145468,1.182248372,2.393485838,0.012712231,DB0122210028411_,4.365190712,0.5123118,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,budesonide,DB01222
,93975,DB01409,10028411,67,5964,33,3933,0.182664972,1.338858605,0.86808009,2.101696673,0.327267997,DB0140910028411_,1.116975883,0.291817463,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tiotropium,DB01409
,94002,DB11089,10038063,49,10126,35,8372,0.583082431,1.157484426,0.734193214,1.842192199,0.731147872,DB1108910038063_,0.313139552,0.146249052,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,94004,DB01175,10069327,49,10675,19,4873,0.601955524,1.177232817,0.679719138,2.119916463,0.746110907,DB0117510069327_,0.292881021,0.163166614,NA,10069327,Product quality issue,10077536,Product issues,Prod,escitalopram,DB01175
,94009,DB00586,10016322,125,6984,33,2772,0.040251616,1.503429311,1.014514572,2.284571134,0.106151672,DB0058610016322_,2.242886338,0.407748706,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,94013,DB00316,10017944,245,65229,91,36862,0.000505003,1.521461863,1.190966887,1.958101419,0.003114197,DB0031610017944_,5.771784035,0.419671625,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,94036,DB00008,10022004,44,1481,58,1618,0.366365396,0.828846194,0.54342768,1.256479718,0.535959297,DB0000810022004_,0.62369706,-0.187720673,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,peginterferon alfa-2a,DB00008
,94042,DB00175,10001949,49,8082,16,6090,0.002483972,2.307522322,1.288484229,4.351587153,0.011607326,DB0017510001949_,4.456118849,0.836174361,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,94043,DB11089,10001949,60,10115,35,8372,0.120691379,1.418854064,0.919020246,2.220815409,0.242406425,DB1108910001949_,1.417139518,0.349849548,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,docusate,DB11089
,94062,DB00175,10048334,37,8094,15,6091,0.048603662,1.856160205,0.993326506,3.643969946,0.122440795,DB0017510048334_,2.100127673,0.618509948,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,94063,DB00264,10048334,77,29530,49,24843,0.128982829,1.322002909,0.911818016,1.932772759,0.254127401,DB0026410048334_,1.369919559,0.279147942,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,94064,DB00788,10048334,54,9302,14,5047,0.010790649,2.092680468,1.145013729,4.083830048,0.037837808,DB0078810048334_,3.274446466,0.738445765,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,94066,DB00331,10052904,121,24825,63,20689,0.002296195,1.600625093,1.170230964,2.207579507,0.010883903,DB0033110052904_,4.520470381,0.470394236,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,94069,DB00331,10040882,40,24906,24,20728,0.211720313,1.387069919,0.815716194,2.40645476,0.363480516,DB0033110040882_,1.012029585,0.32719355,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,94098,DB00795,10013709,1182,3387,371,1132,0.375633592,1.064813746,0.929058419,1.221878348,0.54548377,DB0079510013709_,0.606082227,0.062799897,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,94099,DB00795,10020751,61,4508,13,1490,0.17540482,1.550768229,0.839969877,3.086029919,0.317942121,DB0079510020751_,1.145885921,0.43875044,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,sulfasalazine,DB00795
,94100,DB00795,10021789,80,4489,38,1465,0.066617884,0.687106044,0.459150527,1.044228258,0.155248788,DB0079510021789_,1.862726363,-0.375266641,NA,10021789,Infection,10021881,Infections and infestations,Infec,sulfasalazine,DB00795
,94101,DB00530,10002034,42,1766,34,1234,0.556177042,0.863211653,0.532737224,1.407723991,0.709596813,DB0053010002034_,0.343058339,-0.147095365,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,erlotinib,DB00530
,94102,DB00642,10002034,30,504,24,509,0.485320765,1.262122505,0.702356988,2.290187088,0.64934241,DB0064210002034_,0.431795105,0.232794832,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,pemetrexed,DB00642
,94105,DB00433,10005557,41,7615,24,5996,0.262181488,1.345100135,0.792671465,2.330161108,0.423919074,DB0043310005557_,0.858212706,0.29646846,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,prochlorperazine,DB00433
,94128,DB00433,10020635,25,7631,38,5982,0.01060779,0.515762041,0.298039391,0.878047069,0.037306094,DB0043310020635_,3.288598578,-0.662109781,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,prochlorperazine,DB00433
,94129,DB00497,10020635,40,19227,55,16320,0.022931382,0.617329463,0.399986604,0.945284416,0.068744456,DB0049710020635_,2.677359189,-0.482352422,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,94132,DB00996,10020635,58,38895,57,22368,0.004751813,0.585210308,0.398757747,0.859031294,0.019632413,DB0099610020635_,3.930573351,-0.535783996,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,94144,DB00958,10028372,58,4536,21,2564,0.098253948,1.561091868,0.930718982,2.714621134,0.208253506,DB0095810028372_,1.568999165,0.445385492,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,carboplatin,DB00958
,94162,DB00186,10034474,42,16859,23,9985,0.798706524,1.081534254,0.635251174,1.885182072,0.891294699,DB0018610034474_,0.115080156,0.078380639,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,lorazepam,DB00186
,94163,DB00433,10034474,30,7626,22,5998,0.888994439,1.072539692,0.597614619,1.953488655,0.953939248,DB0043310034474_,0.047155291,0.07002938,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,prochlorperazine,DB00433
,94164,DB00497,10034474,26,19241,30,16345,0.283675353,0.736234666,0.418051797,1.288522409,0.448060972,DB0049710034474_,0.802825958,-0.306206371,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,oxycodone,DB00497
,94166,DB00996,10034474,43,38910,40,22385,0.030223119,0.61848437,0.392512815,0.976424526,0.085173654,DB0099610034474_,2.463063119,-0.480483359,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,gabapentin,DB00996
,94171,DB00497,10043071,98,19169,118,16257,0.011181816,0.704357577,0.532822828,0.929416202,0.038921278,DB0049710043071_,3.246214182,-0.350469131,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,oxycodone,DB00497
,94173,DB00958,10043071,39,4555,47,2538,0.000414552,0.462394416,0.293656857,0.724514897,0.002638697,DB0095810043071_,5.937470117,-0.771337037,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,carboplatin,DB00958
,94191,DB01234,10047924,78,31547,66,32822,0.242678244,1.229575866,0.874161199,1.733983634,0.400892289,DB0123410047924_,0.914062494,0.206669285,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,94195,DB00019,10047943,68,18944,30,9499,0.593306913,1.136550969,0.728915317,1.810851332,0.7393565,DB0001910047943_,0.301975066,0.127998211,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,pegfilgrastim,DB00019
,94197,DB00497,10047943,47,19220,39,16336,1,1.024298435,0.655321592,1.609162746,1,DB0049710047943_,0,0.024007925,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,oxycodone,DB00497
,94201,DB00996,10047943,88,38865,45,22380,0.588736891,1.126102267,0.777346316,1.651328863,0.735582809,DB0099610047943_,0.307092157,0.118762349,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,gabapentin,DB00996
,94216,DB00451,10071134,79,47192,13,15406,0.020645948,1.983707314,1.0955851,3.890387756,0.063361436,DB0045110071134_,2.758899868,0.684967475,NA,10071134,Product physical issue,10077536,Product issues,Prod,levothyroxine,DB00451
,94226,DB00136,10033371,46,2046,25,1657,0.117966458,1.490010385,0.892218381,2.542293309,0.238125282,DB0013610033371_,1.434958349,0.39878309,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,calcitriol,DB00136
,94228,DB00343,10037153,51,8685,17,5078,0.043961956,1.753992141,0.994972898,3.243395368,0.113523789,DB0034310037153_,2.175742867,0.561894413,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,diltiazem,DB00343
,94229,DB00542,10037153,42,1644,8,1416,1.05923499978989e-05,4.520007661,2.087399193,11.18236744,0.00011413,DB0054210037153_,9.078173182,1.508513689,female,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,benazepril,DB00542
,94230,DB00641,10037153,167,13957,90,12385,0.000120883,1.646525287,1.265190686,2.154587523,0.00093784,DB0064110037153_,6.971931258,0.498667181,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,94231,DB00758,10037153,47,8253,48,10026,0.409896666,1.189507479,0.777540745,1.818845576,0.579347952,DB0075810037153_,0.545852028,0.173539338,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,clopidogrel,DB00758
,94233,DB01068,10037153,127,13636,28,6812,3.38502843696848e-05,2.265784006,1.493715217,3.548296746,0.000315516,DB0106810037153_,8.061301608,0.817920838,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,clonazepam,DB01068
,94234,DB01104,10037153,152,15311,47,7239,0.011580534,1.529020337,1.094370981,2.171212044,0.040041348,DB0110410037153_,3.217842659,0.424627228,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,sertraline,DB01104
,94237,DB00641,10043414,36,14088,24,12451,0.302507946,1.325686389,0.768924007,2.3241698,0.468851121,DB0064110043414_,0.757470001,0.281930355,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,94239,DB01068,10043414,44,13719,30,6810,0.215694037,0.728026889,0.447051054,1.200550598,0.368258111,DB0106810043414_,0.998971197,-0.317417297,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,94240,DB05679,10043414,79,6852,78,4831,0.041185272,0.714121612,0.5144073,0.991514409,0.108071766,DB0567910043414_,2.224959773,-0.336702006,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,94241,DB00136,10047895,35,2057,34,1648,0.464147642,0.824776081,0.497168966,1.369570632,0.631313568,DB0013610047895_,0.459952602,-0.192643347,NA,10047895,Weight decreased,10022891,Investigations,Inv,calcitriol,DB00136
,94242,DB00758,10047895,170,8130,192,9882,0.488727812,1.076208862,0.868408076,1.332804665,0.652262546,DB0075810047895_,0.42730812,0.073444552,NA,10047895,Weight decreased,10022891,Investigations,Inv,clopidogrel,DB00758
,94243,DB05679,10047895,72,6859,51,4858,1,0.99987793,0.687462896,1.463641377,1,DB0567910047895_,0,-0.000122078,NA,10047895,Weight decreased,10022891,Investigations,Inv,ustekinumab,DB05679
,94244,DB00051,10061428,150,25581,72,11348,0.609634362,0.924192833,0.692601173,1.242870078,0.751976311,DB0005110061428_,0.285050457,-0.078834536,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,adalimumab,DB00051
,94246,DB00887,10061428,55,2286,39,1776,0.752537678,1.095638711,0.710152275,1.704588729,0.860580938,DB0088710061428_,0.150147608,0.091337491,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,bumetanide,DB00887
,94260,DB06643,10019974,129,52292,12,7503,0.162282394,1.542428922,0.852761021,3.064336567,0.300425589,DB0664310019974_,1.202555179,0.433358396,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,denosumab,DB06643
,94282,DB08910,10022004,39,16705,49,17439,0.395490241,0.830895643,0.530972473,1.29242926,0.565139634,DB0891010022004_,0.570682439,-0.185251072,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,94287,DB00480,10046735,469,66959,379,67283,0.001707017,1.243450269,1.08321927,1.42814411,0.008536711,DB0048010046735_,4.763379519,0.217889991,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,94288,DB00115,10015916,40,18385,14,10458,0.121179262,1.625211975,0.865139004,3.235680879,0.243126243,DB0011510015916_,1.414174454,0.485638253,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,cyanocobalamin,DB00115
,94293,DB00115,10058080,54,18371,25,10447,0.414945441,1.228359399,0.750814939,2.061192017,0.584159441,DB0011510058080_,0.537581318,0.205679457,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,94296,DB08910,10058080,26,16718,35,17453,0.370172877,0.775524003,0.448092456,1.326379895,0.539790524,DB0891010058080_,0.616574134,-0.254216346,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,94305,DB00213,10007617,41,18854,45,13376,0.048243366,0.64641244,0.412592382,1.010160615,0.121792809,DB0021310007617_,2.105433962,-0.436317527,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,94306,DB00264,10007617,165,29442,107,24785,0.037924888,1.29813289,1.011048043,1.672553046,0.101484922,DB0026410007617_,2.287845048,0.260926994,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,metoprolol,DB00264
,94307,DB00425,10007617,249,12446,157,7327,0.500431934,0.933679705,0.759903399,1.149984797,0.661999838,DB0042510007617_,0.412489967,-0.068621827,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,zolpidem,DB00425
,94310,DB00813,10007617,292,10280,388,9780,2.07108881512349e-05,0.715988974,0.611419042,0.837735038,0.000205934,DB0081310007617_,8.487956361,-0.334090512,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,fentanyl,DB00813
,94311,DB00904,10007617,73,22996,55,14401,0.317355086,0.831201318,0.577366853,1.202643394,0.485150543,DB0090410007617_,0.723296039,-0.184883254,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,ondansetron,DB00904
,94316,DB01413,10011906,31,1189,32,1627,0.302720754,1.325468116,0.777458637,2.256955171,0.469052995,DB0141310011906_,0.757039521,0.281765692,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cefepime,DB01413
,94317,DB00433,10038695,70,7586,65,5955,0.338990356,0.845396205,0.593399112,1.20588591,0.508057234,DB0043310038695_,0.677161171,-0.167949879,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,94318,DB01109,10038695,89,4323,104,4166,0.19072178,0.824709823,0.612269525,1.108905573,0.337469167,DB0110910038695_,1.086281129,-0.192723684,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,heparin,DB01109
,94320,DB00512,10040070,95,4642,100,4998,0.885139233,1.02285893,0.761925276,1.372399472,0.952154072,DB0051210040070_,0.049028417,0.022601579,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,vancomycin,DB00512
,94321,DB00813,10040070,49,10523,42,10126,0.600802056,1.122645265,0.727495345,1.739214132,0.745155572,DB0081310040070_,0.294162261,0.115687745,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,fentanyl,DB00813
,94322,DB01109,10040070,33,4379,61,4209,0.002482721,0.520023647,0.329012157,0.808851076,0.011602509,DB0110910040070_,4.45653393,-0.653880994,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,heparin,DB01109
,94323,DB01137,10040070,45,7727,44,5549,0.161137424,0.734479852,0.473098424,1.140883849,0.299013227,DB0113710040070_,1.207267469,-0.308592714,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,levofloxacin,DB01137
,94325,DB01413,10040070,40,1180,38,1621,0.130514703,1.445816524,0.897846661,2.331974493,0.256489431,DB0141310040070_,1.360667822,0.36867423,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,cefepime,DB01413
,94350,DB00335,10074903,33,8433,22,5443,0.89099921,0.968143485,0.547130303,1.744999568,0.954745791,DB0033510074903_,0.046310162,-0.032374975,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,atenolol,DB00335
,94354,DB00641,10020993,38,14086,50,12425,0.068828525,0.670397955,0.427474736,1.043703237,0.159214801,DB0064110020993_,1.837501039,-0.399883781,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,simvastatin,DB00641
,94355,DB00641,10022523,30,14094,24,12451,0.785502335,1.104251003,0.623749862,1.974879354,0.883669115,DB0064110022523_,0.12367259,0.09916728,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,94356,DB00641,10023676,32,14092,66,12409,6.18206430643269e-05,0.42695462,0.270602958,0.661244966,0.000528957,DB0064110023676_,7.5446036,-0.851077548,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,simvastatin,DB00641
,94361,DB01017,10013709,101,1368,36,865,0.003595093,1.773578152,1.188700314,2.698355301,0.015654245,DB0101710013709_,4.157013132,0.572999061,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,minocycline,DB01017
,94362,DB00158,10062352,64,16751,12,8092,0.001304603,2.57632017,1.376952575,5.247263362,0.006850079,DB0015810062352_,4.983495043,0.94636209,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,folic acid,DB00158
,94366,DB00563,10062352,96,46550,21,15327,0.106972525,1.505137518,0.931016843,2.542947073,0.221573902,DB0056310062352_,1.506999103,0.408884268,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,94374,DB01591,10012735,69,1886,29,627,0.287866812,0.791068705,0.500461495,1.278733611,0.452845482,DB0159110012735_,0.792204312,-0.234370457,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,solifenacin,DB01591
,94375,DB00115,10016766,88,18337,45,10427,0.588720629,1.112001557,0.767246529,1.631385939,0.735582809,DB0011510016766_,0.307092157,0.106161596,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,94377,DB00563,10016766,59,46587,20,15328,0.896519286,0.97060442,0.575741748,1.702468843,0.956301489,DB0056310016766_,0.044682051,-0.029836289,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,94379,DB08895,10016766,103,28011,18,6628,0.296419821,1.353984462,0.814877924,2.376466293,0.462315017,DB0889510016766_,0.771508765,0.303051699,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,94380,DB13961,10016766,63,9394,50,6364,0.441722121,0.853604018,0.578687853,1.264976998,0.609894929,DB1396110016766_,0.494468584,-0.158287872,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,94399,DB00203,10013395,31,13847,19,8919,1,1.050920317,0.574832047,1.970193678,1,DB0020310013395_,0,0.049666272,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,sildenafil,DB00203
,94401,DB00203,10070617,40,13838,11,8927,0.009458236,2.345759196,1.18048667,5.072570078,0.034039808,DB0020310070617_,3.380224615,0.8526091,NA,10070617,Device infusion issue,10077536,Product issues,Prod,sildenafil,DB00203
,94404,DB01240,10070617,84,5667,20,1556,0.631882774,1.153179892,0.698966812,1.98984075,0.770695641,DB0124010070617_,0.260461743,0.14252325,NA,10070617,Device infusion issue,10077536,Product issues,Prod,epoprostenol,DB01240
,94412,DB01611,10042945,171,11742,13,2348,0.000194946,2.630209373,1.49432733,5.049343144,0.001410062,DB0161110042945_,6.564121686,0.967063453,NA,10042945,Systemic lupus erythematosus,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,94415,DB00843,10012267,42,2152,60,2113,0.071186644,0.687376521,0.449841316,1.041912095,0.163368485,DB0084310012267_,1.811746987,-0.374873072,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,donepezil,DB00843
,94416,DB01043,10012267,37,1364,42,1368,0.648435891,0.88357522,0.548525905,1.418072059,0.783404381,DB0104310012267_,0.244106266,-0.123778852,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,memantine,DB01043
,94417,DB01104,10012267,26,15437,34,7252,8.29270507878597e-05,0.359261235,0.206892102,0.617198397,0.000679999,DB0110410012267_,7.293418893,-1.02370548,male,10012267,Dementia,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,94424,DB00563,10036018,58,46588,14,15334,0.340362971,1.363557547,0.750913317,2.648081558,0.50959448,DB0056310036018_,0.674140007,0.310097128,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,methotrexate,DB00563
,94431,DB00016,10003658,43,2719,28,2262,0.338586207,1.277534294,0.772871188,2.142861394,0.507657204,DB0001610003658_,0.677948854,0.244931888,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,erythropoietin,DB00016
,94433,DB01075,10003658,104,19844,110,10987,2.79177614230211e-06,0.523463489,0.396070713,0.69146843,3.5561829852392e-05,DB0107510003658_,10.24423769,-0.647287995,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,94434,DB01394,10003658,19,1421,36,1967,0.334828056,0.730634458,0.394119579,1.314255627,0.503977292,DB0139410003658_,0.685224067,-0.313842002,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,colchicine,DB01394
,94437,DB00281,10020642,69,11389,55,5616,0.009483887,0.618629963,0.427146724,0.899733524,0.034125116,DB0028110020642_,3.377721621,-0.480247984,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,lidocaine,DB00281
,94439,DB00343,10020642,43,8693,30,5065,0.466617478,0.835154691,0.511212215,1.380672389,0.633314071,DB0034310020642_,0.456788818,-0.180138313,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,diltiazem,DB00343
,94440,DB00480,10020642,301,67127,202,67460,9.16280193067472e-06,1.497478483,1.248425333,1.799300431,0.000100645,DB0048010020642_,9.203907913,0.403782682,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,94444,DB00016,10021097,46,2716,37,2253,0.911954619,1.031304198,0.651885364,1.641522004,0.96056931,DB0001610021097_,0.040229139,0.030824213,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,erythropoietin,DB00016
,94447,DB01394,10021097,34,1406,33,1970,0.168407353,1.443413117,0.862853547,2.417057584,0.308795764,DB0139410021097_,1.175075178,0.367010529,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,colchicine,DB01394
,94449,DB00016,10021789,22,2740,31,2259,0.07038137,0.585165873,0.321826221,1.047055662,0.161962241,DB0001610021789_,1.820392052,-0.535859929,NA,10021789,Infection,10021881,Infections and infestations,Infec,erythropoietin,DB00016
,94453,DB08910,10021789,242,16502,266,17222,0.591631826,0.949454194,0.793322594,1.135854509,0.737925527,DB0891010021789_,0.303912372,-0.051867992,NA,10021789,Infection,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,94469,DB00016,10033661,31,2731,38,2252,0.113599951,0.672766233,0.403316945,1.114336569,0.231524752,DB0001610033661_,1.463068492,-0.396357361,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,erythropoietin,DB00016
,94470,DB00193,10033661,50,19270,46,8656,0.000557224,0.488255258,0.32029698,0.745830551,0.003375911,DB0019310033661_,5.691089992,-0.71691694,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,tramadol,DB00193
,94471,DB00281,10033661,42,11416,37,5634,0.01158285,0.560211359,0.35104996,0.897409887,0.040046725,DB0028110033661_,3.217708391,-0.579441141,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,lidocaine,DB00281
,94479,DB01234,10013395,33,31592,51,32837,0.080735858,0.672565573,0.420341428,1.062781105,0.179568626,DB0123410013395_,1.717197829,-0.396655666,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,94484,DB00169,10012267,60,38631,44,18131,0.026921717,0.640004561,0.426395038,0.967306584,0.077839328,DB0016910012267_,2.553108477,-0.446279976,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,94485,DB00338,10012267,42,33632,31,22241,0.634622106,0.895964709,0.549808877,1.474659005,0.772842942,DB0033810012267_,0.257679431,-0.109854254,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,94494,DB01240,10055798,82,5669,21,1555,0.903863403,1.071041872,0.654218187,1.827851856,0.95743432,DB0124010055798_,0.043498156,0.068631887,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,epoprostenol,DB01240
,94499,DB00028,10043528,56,13402,24,5591,0.902548884,0.973412476,0.592821588,1.643954997,0.957195726,DB0002810043528_,0.043747388,-0.026947365,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human immunoglobulin g,DB00028
,94500,DB00316,10043528,116,65358,63,36890,0.876249587,1.039269221,0.758085273,1.436160833,0.947029066,DB0031610043528_,0.054425494,0.038517794,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,94502,DB00028,10062355,69,13389,24,5591,0.494685255,1.200524495,0.743965219,2.000110199,0.657155228,DB0002810062355_,0.419835021,0.18275854,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,94512,DB00996,10007617,318,38635,229,22196,0.010949277,0.797800352,0.670470359,0.950437468,0.038274054,DB0099610007617_,3.262983049,-0.225896899,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,gabapentin,DB00996
,94514,DB00722,10013916,33,25370,38,25994,0.636874958,0.889783123,0.540607251,1.457549534,0.774295017,DB0072210013916_,0.255802318,-0.116777528,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,94518,DB00996,10035669,60,38893,64,22361,0.000713518,0.53899054,0.372429468,0.779152585,0.004158038,DB0099610035669_,5.482711924,-0.618057259,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,gabapentin,DB00996
,94521,DB00437,10037423,52,6869,92,11454,0.795595267,0.942492932,0.656624736,1.340321621,0.889335739,DB0043710037423_,0.117280456,-0.059226859,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,94522,DB00999,10037423,54,21376,46,12193,0.048041208,0.669644126,0.443164639,1.015435129,0.121431209,DB0099910037423_,2.10840736,-0.401008862,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,94533,DB00820,10011878,35,11880,17,5799,1,1.004976829,0.547596292,1.914646712,1,DB0082010011878_,0,0.004964486,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,tadalafil,DB00820
,94535,DB00480,10008469,145,67283,123,67539,0.178684421,1.183344291,0.923937852,1.517594808,0.322222832,DB0048010008469_,1.132511947,0.168344575,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,94536,DB00480,10068319,290,67138,156,67506,1.52168713389107e-10,1.869143703,1.532875894,2.286322762,4.81608023050291e-09,DB0048010068319_,19.15130547,0.625480413,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,94545,DB00678,10033295,47,15552,32,10692,1,1.009765516,0.630402227,1.636402495,1,DB0067810033295_,0,0.009718141,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,94548,DB00316,10072268,155,65319,102,36851,0.241757596,0.857324294,0.663237637,1.11216834,0.399896676,DB0031610072268_,0.916549076,-0.153939026,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,94550,DB00338,10072268,24,33650,41,22231,0.000188011,0.386729217,0.223449946,0.655614389,0.001369105,DB0033810072268_,6.593597822,-0.950030529,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,omeprazole,DB00338
,94553,DB01050,10072268,36,18072,15,9356,0.555511717,1.242447772,0.663089532,2.443910825,0.708885594,DB0105010072268_,0.344061127,0.217083443,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,ibuprofen,DB01050
,94554,DB06769,10035664,29,638,50,1006,0.813208789,0.914577419,0.551785536,1.491324764,0.899686135,DB0676910035664_,0.105709316,-0.089293158,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,bendamustine,DB06769
,94557,DB14512,10013700,81,4763,12,2400,1.08764990098795e-05,3.400776885,1.839943611,6.867493409,0.000116625,DB1451210013700_,9.056549757,1.224003901,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,mometasone furoate,DB14512
,94581,DB00537,10062237,38,7519,25,4273,0.599981214,0.863822711,0.50724787,1.495282994,0.744506371,DB0053710062237_,0.29503387,-0.146387727,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,ciprofloxacin,DB00537
,94583,DB00678,10062237,65,15534,63,10661,0.057953012,0.70811147,0.492479087,1.018666697,0.139617334,DB0067810062237_,1.968849929,-0.345153755,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,losartan,DB00678
,94585,DB01015,10062237,53,9834,63,9318,0.227489683,0.797139119,0.541908497,1.168623175,0.382716738,DB0101510062237_,0.960460152,-0.226726062,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,sulfamethoxazole,DB01015
,94587,DB01275,10062237,39,3940,42,3307,0.264875384,0.779418113,0.489573087,1.23817897,0.426830731,DB0127510062237_,0.851367759,-0.249207647,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,hydralazine,DB01275
,94599,DB00112,10009887,37,5896,25,4066,1,1.020636809,0.597153411,1.771878157,1,DB0011210009887_,0,0.020426755,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,94601,DB00958,10009887,43,4551,23,2562,0.898058515,1.052474026,0.61868552,1.834013713,0.956338178,DB0095810009887_,0.044643686,0.051143608,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,carboplatin,DB00958
,94605,DB00916,10013573,139,5184,33,2398,0.000336368,1.94828485,1.320356263,2.950160471,0.002218953,DB0091610013573_,6.110719621,0.666949422,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,metronidazole,DB00916
,94606,DB01212,10013573,31,1988,27,1914,0.791627955,1.10537013,0.635760261,1.932939893,0.887231487,DB0121210013573_,0.119649354,0.100180238,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ceftriaxone,DB01212
,94608,DB00916,10043071,43,5280,19,2412,1,1.03381705,0.588286656,1.882707147,1,DB0091610043071_,0,0.033257827,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,metronidazole,DB00916
,94609,DB01212,10043071,53,1966,36,1905,0.108389546,1.426410337,0.912047911,2.253645596,0.223601555,DB0121210043071_,1.497889583,0.355161034,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,ceftriaxone,DB01212
,94615,DB00476,10008531,168,17089,34,6143,0.001683153,1.77624099,1.221198344,2.652499428,0.008443066,DB0047610008531_,4.774409752,0.574499328,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,94616,DB00641,10008531,103,14021,111,12364,0.149024553,0.818274058,0.618951449,1.080940826,0.282629991,DB0064110008531_,1.263616688,-0.200557964,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,94617,DB00476,10061024,54,17203,31,6146,0.047421688,0.622343691,0.392567017,1.002523611,0.120256653,DB0047610061024_,2.118127046,-0.474262781,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,duloxetine,DB00476
,94619,DB00190,10033425,45,3252,33,4641,0.003753705,1.945943173,1.211426103,3.155226038,0.01620666,DB0019010033425_,4.122333008,0.665746782,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,carbidopa,DB00190
,94622,DB00190,10037087,33,3264,27,4647,0.035183953,1.73992578,1.012376298,3.014833872,0.095800508,DB0019010037087_,2.345487288,0.553842457,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,carbidopa,DB00190
,94639,DB00051,10042772,57,25674,32,11388,0.300960342,0.79012915,0.503476709,1.259815747,0.467261818,DB0005110042772_,0.760865539,-0.235558866,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,94641,DB00404,10042772,112,19780,44,9818,0.201496324,1.263409454,0.883226674,1.835489005,0.35086657,DB0040410042772_,1.047349269,0.233813982,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,94643,DB00814,10042772,46,8241,17,3398,0.781952111,1.115699904,0.626489855,2.078911497,0.881222599,DB0081410042772_,0.126445019,0.109481925,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,94646,DB00316,10047302,50,65424,52,36901,0.002587167,0.542319133,0.360303722,0.815625462,0.011986585,DB0031610047302_,4.423967201,-0.611900644,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,94661,DB00273,10008479,114,8367,21,2172,0.163832759,1.409158177,0.876941036,2.369699546,0.302528651,DB0027310008479_,1.195579293,0.342992489,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,94670,DB00795,10037660,45,4524,18,1485,0.465503314,0.82063285,0.463970408,1.511248997,0.632314471,DB0079510037660_,0.458368428,-0.197679468,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,94672,DB08907,10013573,132,4121,125,3785,0.849109765,0.969895718,0.750515619,1.254003779,0.924884495,DB0890710013573_,0.07808642,-0.03056672,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,canagliflozin,DB08907
,94673,DB08907,10016173,53,4200,18,3892,0.000112108,2.728017514,1.569245372,4.958171064,0.000880154,DB0890710016173_,7.035413666,1.00357516,female,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,canagliflozin,DB08907
,94676,DB00863,10047895,233,10440,161,5679,0.021863668,0.787258428,0.639454348,0.971051476,0.066307433,DB0086310047895_,2.713453272,-0.239198714,NA,10047895,Weight decreased,10022891,Investigations,Inv,ranitidine,DB00863
,94677,DB00190,10013709,387,2910,466,4208,0.012367826,1.200867318,1.038110357,1.388674615,0.042164501,DB0019010013709_,3.166176624,0.183044061,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,94678,DB00423,10013709,122,2345,57,983,0.502664587,0.897247159,0.64380833,1.262747049,0.663796562,DB0042310013709_,0.409779559,-0.108423916,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,methocarbamol,DB00423
,94679,DB00190,10013968,97,3200,80,4594,0.000275444,1.740524732,1.276536937,2.378952302,0.001882239,DB0019010013968_,6.275293199,0.554186638,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carbidopa,DB00190
,94680,DB08907,10013968,48,4205,36,3874,0.380858026,1.228346598,0.778935256,1.952619251,0.550879252,DB0890710013968_,0.596239636,0.205669036,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,canagliflozin,DB08907
,94683,DB00476,10037377,96,17161,44,6133,0.178217421,0.779741683,0.539622211,1.142335732,0.321590286,DB0047610037377_,1.134476946,-0.24879259,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,94686,DB00480,10062237,362,67066,418,67244,0.052436677,0.86832881,0.751937717,1.002365081,0.129581916,DB0048010062237_,2.04344204,-0.141184823,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,94688,DB01611,10060933,57,11856,8,2353,0.501838073,1.414028887,0.67010451,3.43685486,0.663252563,DB0161110060933_,0.410599421,0.346442997,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,94726,DB00575,10011224,98,5146,60,3769,0.291650745,1.196247614,0.856266549,1.68302915,0.457114567,DB0057510011224_,0.782821227,0.17918967,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonidine,DB00575
,94730,DB00341,10043521,64,11341,23,5045,0.416629252,1.237794975,0.756993323,2.091820221,0.58584339,DB0034110043521_,0.534702777,0.213331551,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,94738,DB00921,10069229,69,5776,49,4854,0.40340219,1.183364705,0.806975384,1.746819524,0.573127213,DB0092110069229_,0.556647574,0.168361826,NA,10069229,Product solubility abnormal,10077536,Product issues,Prod,buprenorphine,DB00921
,94749,DB00338,10069326,42,33632,39,22233,0.139725592,0.711937791,0.44917221,1.130751191,0.269426488,DB0033810069326_,1.311459696,-0.339764744,NA,10069326,Product substitution issue,10077536,Product issues,Prod,omeprazole,DB00338
,94750,DB00588,10069326,33,16491,18,8450,0.882459352,0.939404513,0.513461614,1.773070405,0.950859822,DB0058810069326_,0.050388628,-0.062509101,NA,10069326,Product substitution issue,10077536,Product issues,Prod,fluticasone propionate,DB00588
,94753,DB00334,10003549,65,2784,50,2762,0.188058559,1.289665764,0.874765151,1.91119389,0.334115659,DB0033410003549_,1.096268062,0.254383087,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,olanzapine,DB00334
,94762,DB00182,10020642,59,5135,44,2808,0.121260077,0.733311228,0.486454809,1.112554125,0.24325125,DB0018210020642_,1.413660417,-0.310185072,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,amphetamine,DB00182
,94763,DB00422,10020642,40,3395,33,2916,0.906381116,1.041104882,0.638301113,1.708578019,0.958220151,DB0042210020642_,0.042677724,0.040282535,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,methylphenidate,DB00422
,94764,DB00422,10044565,68,3367,37,2912,0.023366568,1.589364438,1.046255455,2.448431079,0.06972491,DB0042210044565_,2.66319763,0.463334212,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,methylphenidate,DB00422
,94768,DB00182,10061920,23,5171,36,2816,9.09747962188946e-05,0.347971511,0.196425657,0.604828083,0.000735663,DB0018210061920_,7.214738451,-1.055634668,male,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,94770,DB00005,10000269,77,128005,25,42394,1,1.020071726,0.64219297,1.672436489,1,DB0000510000269_,0,0.019872944,NA,10000269,Abscess,10021881,Infections and infestations,Infec,etanercept,DB00005
,94771,DB06285,10003988,202,8648,29,1077,0.458761849,0.867492826,0.582382633,1.33536185,0.626136258,DB0628510003988_,0.468187267,-0.142148037,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,teriparatide,DB06285
,94774,DB00186,10013710,205,16696,176,9832,0.000335872,0.685950275,0.55715264,0.845162124,0.002216243,DB0018610013710_,6.111941742,-0.376950139,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,94775,DB00313,10013710,90,1149,137,1380,0.095104841,0.789075513,0.590949529,1.049622519,0.203359335,DB0031310013710_,1.592780739,-0.236893255,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,valproic acid,DB00313
,94776,DB00319,10013710,35,1357,31,1822,0.102671954,1.515689946,0.902774932,2.555834865,0.215021298,DB0031910013710_,1.537018193,0.415870745,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,piperacillin,DB00319
,94777,DB00349,10013710,36,986,33,911,1,1.007925563,0.605182308,1.683628308,1,DB0034910013710_,0,0.007894321,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,clobazam,DB00349
,94799,DB00364,10046571,90,2660,17,1383,4.285316890709e-05,2.75198808,1.618887058,4.951616794,0.000387211,DB0036410046571_,7.856541907,1.012323589,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,sucralfate,DB00364
,94800,DB01036,10046571,76,1425,10,412,0.016172099,2.196752223,1.118312076,4.80900385,0.052272949,DB0103610046571_,2.951276267,0.786980007,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,tolterodine,DB01036
,94801,DB01238,10046571,82,5168,13,3489,3.38356254192699e-08,4.257861612,2.352448575,8.348178971,6.76326550680995e-07,DB0123810046571_,14.20658981,1.448767065,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,aripiprazole,DB01238
,94821,DB00706,10000081,13,1062,165,15760,0.536205375,1.169193696,0.607502015,2.06431615,0.692536584,DB0070610000081_,0.367394214,0.156314362,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,tamsulosin,DB00706
,94824,DB00572,10012174,111,2791,78,2048,0.821982726,1.044233279,0.770059514,1.421723434,0.905202084,DB0057210012174_,0.099597063,0.043282912,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,atropine,DB00572
,94825,DB00836,10012174,175,5360,120,3955,0.550322953,1.076074807,0.844893113,1.374181065,0.704616791,DB0083610012174_,0.350101182,0.073319982,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,loperamide,DB00836
,94846,DB01076,10033775,241,25506,150,25433,5.71590736390244e-06,1.602044193,1.300227666,1.979126474,6.64496351438194e-05,DB0107610033775_,9.619066264,0.471280434,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,94851,DB00370,10040108,44,4497,20,3643,0.031946976,1.782075878,1.026348112,3.197892218,0.088991763,DB0037010040108_,2.419211469,0.577778908,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,mirtazapine,DB00370
,94861,DB00215,10017955,61,11042,43,5233,0.057442328,0.672307493,0.446982012,1.019083835,0.138609346,DB0021510017955_,1.976095767,-0.397039464,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,94862,DB00215,10021097,167,10936,92,5184,0.2548909,0.860486587,0.661683135,1.124770401,0.415613933,DB0021510021097_,0.877998496,-0.150257251,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,citalopram,DB00215
,94872,DB00480,10005003,7,67421,43,67619,2.09280477846835e-07,0.163273775,0.061973305,0.366125288,3.53530678676353e-06,DB0048010005003_,12.55271048,-1.812326887,male,10005003,Bladder cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,94875,DB01076,10005003,14,25733,37,25546,0.001150001,0.375616846,0.18756259,0.711596347,0.00618598,DB0107610005003_,5.085469904,-0.979185682,NA,10005003,Bladder cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,atorvastatin,DB01076
,94877,DB08907,10003549,36,4217,37,3873,0.640002951,0.893616006,0.547588431,1.457004087,0.777057823,DB0890710003549_,0.252240513,-0.112479119,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,canagliflozin,DB08907
,94879,DB01098,10013781,50,8099,39,7170,0.59512154,1.134979955,0.730830588,1.774123753,0.740784206,DB0109810013781_,0.300045916,0.12661499,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,94882,DB00047,10013950,31,9254,34,8484,0.534425806,0.835909279,0.496355596,1.402988681,0.691005466,DB0004710013950_,0.369607546,-0.179235189,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,94883,DB00331,10013950,128,24818,96,20656,0.459836533,1.109698943,0.84448496,1.462416011,0.62725043,DB0033110013950_,0.466409408,0.104088756,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,94887,DB00654,10037844,79,3737,46,2552,0.409240171,1.172751001,0.802242825,1.731899989,0.578646793,DB0065410037844_,0.547063017,0.159352272,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,latanoprost,DB00654
,94888,DB08907,10037844,122,4131,98,3812,0.338307643,1.148745578,0.869963967,1.52006752,0.507401115,DB0890710037844_,0.678453434,0.138670545,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,canagliflozin,DB08907
,94890,DB00264,10040882,45,29562,46,24846,0.399641645,0.822205395,0.532621507,1.268462255,0.569508303,DB0026410040882_,0.562981917,-0.195765043,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,94896,DB00654,10047700,52,3764,30,2568,0.498623131,1.182515099,0.738188186,1.92564208,0.660467093,DB0065410047700_,0.414807978,0.16764361,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,latanoprost,DB00654
,94897,DB00047,10062355,49,9236,42,8476,0.753729053,1.070687892,0.693675191,1.658985092,0.861512324,DB0004710062355_,0.149065918,0.068301331,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,94898,DB00331,10062355,123,24823,83,20669,0.141497078,1.233928167,0.925886377,1.651340167,0.271924745,DB0033110062355_,1.302229925,0.210202712,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,94900,DB01098,10062355,56,8093,42,7167,0.477454368,1.180760023,0.77629714,1.808209796,0.642759952,DB0109810062355_,0.441983949,0.166158318,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,94904,DB06605,10028372,109,13964,91,12942,0.478187862,1.110117895,0.83179707,1.484516049,0.643500215,DB0660510028372_,0.440832918,0.104466221,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,94905,DB06769,10008531,25,642,43,1013,0.800130535,0.917404775,0.531433227,1.553442226,0.891935108,DB0676910008531_,0.114361898,-0.086206492,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,bendamustine,DB06769
,94907,DB06769,10028813,35,632,35,1021,0.059547641,1.614978469,0.970534348,2.687687061,0.142648104,DB0676910028813_,1.947374491,0.479321625,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,bendamustine,DB06769
,94910,DB08932,10060820,53,19390,14,6583,0.482443752,1.285244721,0.702426057,2.509960532,0.646843021,DB0893210060820_,0.435651639,0.250949145,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,94911,DB00152,10013709,27,804,35,829,0.437894118,0.795524364,0.458509315,1.366681906,0.606365534,DB0015210013709_,0.500272284,-0.228753805,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,thiamine,DB00152
,94912,DB00328,10013709,42,718,53,762,0.458950143,0.841108465,0.540009402,1.303020264,0.626333922,DB0032810013709_,0.467871628,-0.173034656,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,indomethacin,DB00328
,94913,DB00567,10013709,145,4374,67,2014,1,0.99649268,0.737158172,1.358558729,1,DB0056710013709_,0,-0.003513485,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,94927,DB01076,10043882,57,25690,40,25543,0.103614106,1.416830395,0.928888282,2.179640257,0.216425365,DB0107610043882_,1.530509527,0.34842226,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,atorvastatin,DB01076
,94929,DB08895,10012378,404,27710,76,6570,0.06982756,1.260355252,0.982709219,1.634863746,0.160981709,DB0889510012378_,1.826464529,0.231393627,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,tofacitinib,DB08895
,94933,DB00996,10060800,171,38782,64,22361,0.002776811,1.540544096,1.14896408,2.087669002,0.012691441,DB0099610060800_,4.366827422,0.432135663,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,gabapentin,DB00996
,94934,DB08895,10060800,104,28010,7,6639,0.000230722,3.521416616,1.648704779,8.979275896,0.001623701,DB0889510060800_,6.42304689,1.258863356,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,tofacitinib,DB08895
,94938,DB11089,10000891,26,10149,31,8376,0.183266978,0.692210668,0.394405818,1.205735202,0.327966539,DB1108910000891_,1.11484369,-0.367864936,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,docusate,DB11089
,94967,DB00153,10003549,231,7192,137,3302,0.022450695,0.774188036,0.621357869,0.967460212,0.067616626,DB0015310003549_,2.693901382,-0.255940495,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,94968,DB11093,10003549,63,1594,28,632,0.636065824,0.892147784,0.557143565,1.460838237,0.773810891,DB1109310003549_,0.256427762,-0.114123483,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,calcium citrate,DB11093
,94969,DB11093,10003988,55,1602,13,647,0.10088121,1.708331522,0.913676093,3.432604816,0.212126425,DB1109310003988_,1.550572836,0.535517176,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium citrate,DB11093
,94971,DB06643,10013990,58,52363,11,7504,0.364373526,0.755625701,0.392461813,1.597413104,0.534000063,DB0664310013990_,0.627359322,-0.280209131,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,denosumab,DB06643
,94974,DB11093,10033425,68,1589,13,647,0.011709724,2.129251454,1.155772173,4.232112535,0.040369684,DB1109310033425_,3.209676183,0.755770488,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium citrate,DB11093
,94989,DB14126,10071404,28,943,39,1237,0.900518894,0.941797411,0.553774159,1.583069871,0.956698706,DB1412610071404_,0.044266769,-0.05996509,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,tenofovir,DB14126
,94990,DB00005,10025650,86,127996,47,42372,0.006660018,0.605737995,0.419651043,0.883916671,0.025760954,DB0000510025650_,3.658895338,-0.501307738,NA,10025650,Malignant melanoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,etanercept,DB00005
,94996,DB00541,10028116,62,3072,141,4156,0.00067413,0.59491847,0.432382079,0.810692045,0.003970757,DB0054110028116_,5.528798555,-0.519330908,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,vincristine,DB00541
,94998,DB00541,10033661,124,3010,175,4122,0.81138072,0.970343506,0.760808024,1.234622584,0.898590302,DB0054110033661_,0.106928075,-0.03010514,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,vincristine,DB00541
,95014,DB00688,10040753,44,6446,23,5355,0.08433172,1.589192728,0.937692597,2.760956889,0.185618762,DB0068810040753_,1.684060378,0.463226169,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,95017,DB00480,10014625,25,67403,35,67627,0.244998388,0.716664183,0.411116744,1.232208621,0.403748128,DB0048010014625_,0.906964041,-0.333147913,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,95018,DB01234,10014625,78,31547,85,32803,0.814073045,0.954169359,0.692316962,1.313589616,0.900282312,DB0123410014625_,0.105046885,-0.046914098,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,95023,DB00181,10074903,61,9795,20,5851,0.020719828,1.821838632,1.082757331,3.191413833,0.063545962,DB0018110074903_,2.755991817,0.599846229,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,95027,DB06403,10025127,124,21347,44,6617,0.466304595,0.87354734,0.613984795,1.263364328,0.633093464,DB0640310025127_,0.457137215,-0.135192955,NA,10025127,Lung transplant,10042613,Surgical and medical procedures,Surg,ambrisentan,DB06403
,95028,DB00182,10028372,44,5150,17,2835,0.229505528,1.424726522,0.796003543,2.665168616,0.385306601,DB0018210028372_,0.953715895,0.353979881,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,amphetamine,DB00182
,95029,DB00182,10028411,38,5156,17,2835,0.572055566,1.228991081,0.675673395,2.326657235,0.722122,DB0018210028411_,0.325561179,0.206193573,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,amphetamine,DB00182
,95030,DB00182,10033425,68,5126,20,2832,0.013249764,1.878290601,1.124175429,3.272617634,0.044540564,DB0018210033425_,3.11135496,0.630362108,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,amphetamine,DB00182
,95031,DB01175,10037844,250,10474,94,4798,0.112514013,1.218278091,0.954861813,1.565243001,0.229846182,DB0117510037844_,1.470344969,0.197438461,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,escitalopram,DB01175
,95033,DB01175,10039073,56,10668,6,4886,8.8564580754258e-05,4.274847645,1.843631587,12.15010683,0.000719382,DB0117510039073_,7.237118111,1.452748463,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,95056,DB01220,10010305,38,1256,45,1091,0.17982055,0.733609469,0.459773005,1.1650883,0.323632971,DB0122010010305_,1.128145212,-0.309778451,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,rifaximin,DB01220
,95063,DB00338,10012374,85,33589,36,22236,0.025419079,1.563047918,1.046440119,2.377726337,0.074415603,DB0033810012374_,2.598089643,0.446637709,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,95065,DB00924,10012374,40,10122,11,4240,0.280943923,1.523230791,0.76609597,3.294886611,0.444869485,DB0092410012374_,0.809974333,0.420833599,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,95072,DB00422,10028810,48,3387,15,2934,0.000312645,2.771484669,1.521848132,5.341288171,0.002087607,DB0042210028810_,6.171736756,1.019383158,female,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,methylphenidate,DB00422
,95073,DB00924,10028810,145,10017,52,4199,0.386794992,1.168867583,0.84409816,1.640577895,0.556861912,DB0092410028810_,0.585437983,0.156035402,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,cyclobenzaprine,DB00924
,95074,DB06637,10028810,49,6113,14,2005,0.76950356,1.14794248,0.622070863,2.256481821,0.873773071,DB0663710028810_,0.134934581,0.137971192,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,dalfampridine,DB06637
,95075,DB00422,10035664,73,3362,49,2900,0.199309575,1.285019121,0.879410452,1.891870171,0.348235321,DB0042210035664_,1.054876818,0.250773598,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,methylphenidate,DB00422
,95077,DB00169,10048865,130,38561,49,18126,0.199549802,1.247064853,0.890939963,1.770466654,0.348505726,DB0016910048865_,1.054100619,0.220792673,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,cholecalciferol,DB00169
,95078,DB00338,10048865,90,33584,65,22207,0.62221809,0.915562048,0.657785689,1.280354035,0.762417664,DB0033810048865_,0.271260759,-0.088217142,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,omeprazole,DB00338
,95098,DB00115,10004146,34,18391,21,10451,0.779817156,0.92005552,0.518492004,1.669112856,0.880132524,DB0011510004146_,0.127682787,-0.083321263,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyanocobalamin,DB00115
,95102,DB00115,10047571,162,18263,62,10410,0.00787481,1.489348033,1.103716043,2.031455056,0.029408166,DB0011510047571_,3.526482898,0.398338463,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,cyanocobalamin,DB00115
,95103,DB00343,10047571,52,8684,20,5075,0.113208285,1.519417473,0.890494384,2.690090595,0.230896587,DB0034310047571_,1.465785343,0.41832702,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,diltiazem,DB00343
,95105,DB00761,10047571,104,15203,23,8602,1.10117608284833e-05,2.558353449,1.615174909,4.216080159,0.000117948,DB0076110047571_,9.045267602,0.939363867,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,potassium chloride,DB00761
,95108,DB00213,10015150,132,18763,65,13356,0.016500875,1.445538006,1.065250614,1.97834997,0.053097326,DB0021310015150_,2.935628706,0.368481575,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,95110,DB00813,10015150,57,10515,22,10146,0.000164249,2.500069107,1.503179115,4.297941638,0.001219226,DB0081310015150_,6.709539372,0.916318374,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,fentanyl,DB00813
,95111,DB01069,10015150,76,6624,7,2388,7.62851288048328e-05,3.913839507,1.806454134,10.07760626,0.000632242,DB0106910015150_,7.366238771,1.364518863,female,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,promethazine,DB01069
,95114,DB00213,10031252,26,18869,30,13391,0.077426807,0.615082228,0.349240775,1.076516827,0.173982784,DB0021310031252_,1.74879893,-0.485999316,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,95116,DB00316,10031252,84,65390,70,36883,0.018444054,0.676887658,0.486864978,0.943473096,0.057952538,DB0031610031252_,2.848130914,-0.390249961,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,95118,DB00451,10031252,74,47197,25,15394,0.907027747,0.965446188,0.605943897,1.586711673,0.958537515,DB0045110031252_,0.042346578,-0.035164913,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,95119,DB00695,10031252,50,27999,34,20494,0.825210222,1.076418486,0.682276335,1.716973662,0.90753962,DB0069510031252_,0.097018056,0.073639314,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,furosemide,DB00695
,95123,DB00169,10038063,93,38598,47,18128,0.716731554,0.929333347,0.647298343,1.350052449,0.83251017,DB0016910038063_,0.183309841,-0.073287781,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,95161,DB00295,10058080,38,14625,16,9586,0.163336427,1.556672626,0.846988811,2.992158975,0.301845396,DB0029510058080_,1.197840326,0.442550611,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,morphine,DB00295
,95190,DB11089,10018627,17,10158,36,8371,0.001254679,0.389166639,0.204824444,0.711584352,0.006628991,DB1108910018627_,5.016302649,-0.943747649,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,95191,DB00814,10025482,249,8038,69,3346,0.002637142,1.502174288,1.142487019,1.997003857,0.012171602,DB0081410025482_,4.408649769,0.406913584,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,95193,DB09053,10025482,45,2240,57,3995,0.096213962,1.407881112,0.927366235,2.126258027,0.205041672,DB0905310025482_,1.584542043,0.342085817,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ibrutinib,DB09053
,95194,DB01015,10033371,231,9656,114,9267,3.39683461665554e-09,1.944609134,1.544241632,2.460164154,8.4711383205684e-08,DB0101510033371_,16.28401585,0.665060997,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,95196,DB09053,10033371,44,2241,54,3998,0.071641794,1.453499984,0.950132545,2.213129189,0.164133579,DB0905310033371_,1.807074677,0.37397443,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ibrutinib,DB09053
,95198,DB00814,10040047,49,8238,32,3383,0.049024117,0.628847122,0.393946027,1.016542251,0.123163576,DB0081410040047_,2.094241918,-0.463867101,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,meloxicam,DB00814
,95199,DB01015,10040047,152,9735,197,9184,0.003501914,0.727918409,0.584016707,0.905854502,0.015331083,DB0101510040047_,4.177872947,-0.317566312,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,95201,DB09053,10040047,51,2234,118,3934,0.12264115,0.761127401,0.534673719,1.070478438,0.24520767,DB0905310040047_,1.405649795,-0.272954522,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ibrutinib,DB09053
,95205,DB00567,10030124,45,4474,27,2054,0.307348813,0.765166601,0.463147952,1.286455202,0.474477432,DB0056710030124_,0.745541223,-0.26766169,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,95207,DB00904,10061024,88,22981,78,14378,0.030598132,0.705884089,0.514077879,0.970769402,0.086022985,DB0090410061024_,2.453140746,-0.348304235,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,ondansetron,DB00904
,95210,DB00820,10008629,40,11875,14,5802,0.312418059,1.395960467,0.742790103,2.780343023,0.47991634,DB0082010008629_,0.734143481,0.333582685,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,tadalafil,DB00820
,95224,DB01212,10016256,57,1962,44,1897,0.313371063,1.252463481,0.825868038,1.91042695,0.480908945,DB0121210016256_,0.73207733,0.225112397,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ceftriaxone,DB01212
,95243,DB08877,10021789,27,3262,32,3197,0.514220527,0.826962527,0.47544738,1.428446375,0.674213072,DB0887710021789_,0.394209088,-0.189995897,NA,10021789,Infection,10021881,Infections and infestations,Infec,ruxolitinib,DB08877
,95244,DB00542,10037087,40,1646,24,1400,0.205270003,1.417419126,0.829166906,2.471112967,0.355483069,DB0054210037087_,1.034277657,0.348837701,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,benazepril,DB00542
,95264,DB00264,10005734,142,29465,134,24758,0.363587559,0.890418142,0.697778625,1.136799787,0.533160333,DB0026410005734_,0.628933087,-0.116064104,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,metoprolol,DB00264
,95265,DB00331,10005734,68,24878,76,20676,0.078656792,0.743622404,0.52782736,1.045841597,0.176069302,DB0033110005734_,1.736877599,-0.296221895,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,metformin,DB00331
,95269,DB01098,10005734,36,8113,29,7180,0.803545685,1.098583131,0.654245601,1.859554762,0.893716343,DB0109810005734_,0.112366844,0.094021287,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,rosuvastatin,DB01098
,95270,DB00153,10013786,63,7360,13,3426,0.006069944,2.255690164,1.226723545,4.474337752,0.023884501,DB0015310013786_,3.734525507,0.813455986,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,ergocalciferol,DB00153
,95272,DB00331,10013786,110,24836,77,20675,0.269679208,1.18922479,0.880206281,1.613579601,0.432253063,DB0033110013786_,0.838744067,0.173301658,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,95273,DB00399,10013786,55,6937,25,4973,0.068163871,1.577077202,0.964803968,2.645199536,0.157997121,DB0039910013786_,1.845178468,0.455573262,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,zoledronic acid,DB00399
,95274,DB00695,10013786,136,27913,87,20441,0.341979574,1.14472808,0.867754177,1.516929797,0.511199562,DB0069510013786_,0.670995232,0.135167124,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,95277,DB01098,10013786,40,8109,27,7182,0.326525332,1.312097085,0.78462809,2.225760347,0.495009277,DB0109810013786_,0.703178774,0.271626685,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,rosuvastatin,DB01098
,95279,DB00331,10016326,41,24905,21,20731,0.074215924,1.625147194,0.938048577,2.895756715,0.168554505,DB0033110016326_,1.780496109,0.485598393,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,95287,DB00695,10023676,77,27972,57,20471,1,0.988622797,0.692511341,1.418525134,1,DB0069510023676_,0,-0.011442419,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,95294,DB00695,10027417,44,28005,56,20472,0.00608355,0.574386103,0.377823953,0.868324257,0.023932665,DB0069510027417_,3.732511025,-0.554453455,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,95313,DB00924,10028596,53,10109,35,4216,0.045358897,0.631561003,0.403796492,0.998913602,0.116272539,DB0092410028596_,2.151818368,-0.459560742,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,cyclobenzaprine,DB00924
,95314,DB01222,10028596,44,9230,40,5365,0.041647672,0.639431217,0.406545548,1.008244692,0.109007622,DB0122210028596_,2.216337471,-0.44717622,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,budesonide,DB01222
,95322,DB00222,10061818,28,3178,34,3094,0.444237559,0.80179191,0.467123693,1.36590935,0.612263546,DB0022210061818_,0.490592458,-0.220906168,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,95323,DB00727,10061818,26,3817,34,4139,0.51791188,0.829236169,0.476870225,1.426365801,0.677380677,DB0072710061818_,0.389521865,-0.18725028,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,95324,DB00956,10061818,30,5784,35,3432,0.006803163,0.508621684,0.301073621,0.854470453,0.026202845,DB0095610061818_,3.641887289,-0.676050793,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,95325,DB01039,10061818,22,2951,33,3018,0.177024417,0.681848704,0.377751639,1.208354404,0.320063751,DB0103910061818_,1.139235082,-0.382947487,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,95326,DB01592,10061818,45,6231,43,3024,0.001915872,0.50791089,0.326094329,0.79211033,0.00939703,DB0159210061818_,4.667361547,-0.67744926,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,95328,DB08910,10038695,49,16695,65,17423,0.222834201,0.78672534,0.531286782,1.158387311,0.37699591,DB0891010038695_,0.97552094,-0.239876088,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,95330,DB00338,10005169,45,33629,40,22232,0.183876909,0.743749956,0.474746051,1.168867315,0.328779874,DB0033810005169_,1.112366829,-0.296050381,NA,10005169,Blindness,10015919,Eye disorders,Eye,omeprazole,DB00338
,95332,DB00635,10005169,69,32984,39,23755,0.242277025,1.274189876,0.84799043,1.939125371,0.400531564,DB0063510005169_,0.914962703,0.242310585,NA,10005169,Blindness,10015919,Eye disorders,Eye,prednisone,DB00635
,95367,DB00727,10010774,67,3776,67,4106,0.663258772,1.087371235,0.760999491,1.553723252,0.794755508,DB0072710010774_,0.229720749,0.083763073,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,nitroglycerin,DB00727
,95369,DB11089,10013700,92,10083,44,8363,0.002405236,1.734179417,1.196677165,2.546756913,0.011311798,DB1108910013700_,4.481909004,0.550534343,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,docusate,DB11089
,95376,DB00126,10003658,124,10047,85,5860,0.279053226,0.850886501,0.639198536,1.137202764,0.442916219,DB0012610003658_,0.814374648,-0.16147653,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ascorbic acid,DB00126
,95379,DB09270,10020772,46,3068,36,2332,0.91093772,0.971238025,0.612085145,1.551830737,0.959929359,DB0927010020772_,0.040895582,-0.029183707,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ubidecarenone,DB09270
,95380,DB01098,10037377,24,8125,50,7159,0.00040314,0.422952821,0.248320436,0.702063864,0.0025798,DB0109810037377_,5.96004332,-0.860494639,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,95382,DB00126,10064355,41,10130,32,5913,0.225489956,0.747913481,0.459027775,1.2283701,0.380265198,DB0012610064355_,0.966886381,-0.290467974,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,ascorbic acid,DB00126
,95385,DB01136,10064355,46,9838,52,11063,1,0.994765287,0.653531991,1.509855805,1,DB0113610064355_,0,-0.005248462,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,95387,DB00213,10048865,44,18851,37,13384,0.498461499,0.844319216,0.53256445,1.345349929,0.660286272,DB0021310048865_,0.415081793,-0.169224638,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,pantoprazole,DB00213
,95392,DB00215,10008469,53,11050,14,5262,0.049410285,1.802695945,0.984920515,3.521504015,0.12390873,DB0021510008469_,2.088210035,0.589283292,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,95407,DB08895,10000060,142,27972,16,6630,0.003079396,2.103508783,1.250325379,3.783233999,0.013826773,DB0889510000060_,4.281148475,0.7436068,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,95416,DB00864,10060872,32,6837,39,8353,1,1.002448882,0.607230192,1.644011833,1,DB0086410060872_,0,0.002445888,NA,10060872,Transplant failure,10022117,"Injury, poisoning and procedural complications",Inj&P,tacrolimus,DB00864
,95417,DB00563,10047899,351,46295,63,15285,2.53084313972372e-06,1.839380241,1.402359329,2.446675032,3.25615330042281e-05,DB0056310047899_,10.33237894,0.609428689,NA,10047899,Weight increased,10022891,Investigations,Inv,methotrexate,DB00563
,95421,DB08934,10065154,26,4463,38,6166,0.899185192,0.945289309,0.550256636,1.600705049,0.956490275,DB0893410065154_,0.044484657,-0.056264251,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,sofosbuvir,DB08934
,95424,DB00997,10028411,48,5283,13,3501,0.003506061,2.44663181,1.302368396,4.930059294,0.015339017,DB0099710028411_,4.177355572,0.894712307,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,doxorubicin,DB00997
,95425,DB00773,10037660,103,2220,156,2671,0.083549463,0.794425629,0.609287172,1.032332523,0.18437559,DB0077310037660_,1.690780354,-0.230135905,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,etoposide,DB00773
,95426,DB00531,10068319,31,7221,26,6490,0.894419032,1.071627625,0.614999867,1.881170989,0.955931269,DB0053110068319_,0.045069263,0.069178638,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclophosphamide,DB00531
,95439,DB00853,10016256,114,1707,168,2098,0.153613872,0.834040162,0.64593647,1.073898029,0.288956999,DB0085310016256_,1.241477393,-0.181473722,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,temozolomide,DB00853
,95441,DB00853,10047895,25,1796,41,2225,0.318161794,0.755456764,0.438483202,1.277874112,0.486143453,DB0085310047895_,0.721251528,-0.280432728,NA,10047895,Weight decreased,10022891,Investigations,Inv,temozolomide,DB00853
,95442,DB01202,10047895,84,6630,82,5636,0.389179093,0.870819933,0.633251882,1.197881552,0.559069406,DB0120210047895_,0.581481652,-0.138320059,NA,10047895,Weight decreased,10022891,Investigations,Inv,levetiracetam,DB01202
,95445,DB01202,10047942,63,6651,32,5686,0.017195203,1.68302922,1.081349988,2.666329933,0.054878084,DB0120210047942_,2.902641206,0.520595277,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,levetiracetam,DB01202
,95447,DB00853,10061428,43,1778,43,2223,0.324692162,1.25020567,0.79597079,1.963707329,0.49316074,DB0085310061428_,0.706920113,0.223308074,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,temozolomide,DB00853
,95454,DB06218,10013573,75,1619,47,1389,0.114830144,1.368910276,0.93103383,2.030318909,0.233389549,DB0621810013573_,1.455046337,0.314015005,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lacosamide,DB06218
,95458,DB00316,10056871,45,65429,11,36942,0.011523704,2.30975647,1.176053927,4.953232661,0.039878949,DB0031610056871_,3.221906696,0.837142095,NA,10056871,Device failure,10077536,Product issues,Prod,acetaminophen,DB00316
,95467,DB00564,10021097,39,2565,25,1438,0.601692169,0.874607053,0.513697406,1.514518316,0.745960364,DB0056410021097_,0.293082812,-0.133980576,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,carbamazepine,DB00564
,95469,DB00374,10011703,49,17667,25,5699,0.076758747,0.63226857,0.382599891,1.069366967,0.172814019,DB0037410011703_,1.755539296,-0.458441022,NA,10011703,Cyanosis,10047065,Vascular disorders,Vasc,treprostinil,DB00374
,95470,DB00559,10011703,37,9622,25,3281,0.012098413,0.504671268,0.295292946,0.876097237,0.041401743,DB0055910011703_,3.184432304,-0.683848017,NA,10011703,Cyanosis,10047065,Vascular disorders,Vasc,bosentan,DB00559
,95473,DB00230,10005956,43,19631,13,8638,0.308809929,1.455462547,0.767694696,2.951710509,0.476130278,DB0023010005956_,0.742063768,0.375323752,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,95485,DB01234,10005956,40,31585,59,32829,0.088132145,0.704674758,0.459384647,1.071001789,0.192133485,DB0123410005956_,1.649564915,-0.350018919,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,95490,DB00480,10052251,98,67330,98,67564,1,1.003475488,0.75044174,1.341799618,1,DB0048010052251_,0,0.003469463,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,95494,DB00695,10052251,49,28000,21,20507,0.039642643,1.708892871,1.005500556,3.001068925,0.104945802,DB0069510052251_,2.254311233,0.535845717,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,95501,DB00203,10000081,287,13591,100,8838,2.94155064607459e-08,1.866260797,1.478883479,2.371269518,5.95216772379296e-07,DB0020310000081_,14.33434017,0.623936855,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,95511,DB00087,10012735,47,1322,16,731,0.108372683,1.62394636,0.896640753,3.091178903,0.223575541,DB0008710012735_,1.498005932,0.484859212,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,alemtuzumab,DB00087
,95519,DB00864,10014625,85,6784,74,8318,0.036921992,1.408335206,1.017310404,1.953460579,0.099435919,DB0086410014625_,2.30824187,0.342408302,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,tacrolimus,DB00864
,95522,DB01024,10021097,29,2182,43,2077,0.074360018,0.642034724,0.384980041,1.056754365,0.168794256,DB0102410021097_,1.779074728,-0.443112889,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,mycophenolic acid,DB01024
,95524,DB00864,10028411,43,6826,47,8345,0.597248448,1.118476946,0.721118256,1.730848734,0.742475406,DB0086410028411_,0.297765533,0.11196789,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tacrolimus,DB00864
,95528,DB00254,10040047,44,5891,47,3341,0.002957134,0.530957202,0.343035706,0.820527974,0.013341619,DB0025410040047_,4.31686689,-0.63307386,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,doxycycline,DB00254
,95546,DB08932,10002855,350,19093,63,6534,8.10739048712e-07,1.901262061,1.448024449,2.531305247,1.19051820644664e-05,DB0893210002855_,11.33853679,0.642517908,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,macitentan,DB08932
,95547,DB01234,10000496,30,31595,22,32866,0.215490214,1.418477478,0.791111758,2.581359125,0.367981827,DB0123410000496_,0.999721726,0.349584098,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,95551,DB00437,10005750,45,6876,59,11487,0.224229631,1.274143005,0.843754205,1.912639955,0.378797286,DB0043710005750_,0.970754083,0.2422738,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,allopurinol,DB00437
,95558,DB01225,10003549,135,4909,134,4506,0.536487314,0.924777887,0.720126486,1.187581694,0.692783318,DB0122510003549_,0.367038002,-0.078201692,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,95559,DB01060,10003988,134,8453,67,5014,0.270664511,1.186349926,0.876364234,1.618854464,0.43334589,DB0106010003988_,0.836219048,0.170881304,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,amoxicillin,DB01060
,95567,DB00381,10017822,32,29328,20,22867,0.486082811,1.247511698,0.691731759,2.302064065,0.649960453,DB0038110017822_,0.430843759,0.221150926,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,95572,DB00381,10018830,39,29321,34,22853,0.638757294,0.89402891,0.549704465,1.460489533,0.775865779,DB0038110018830_,0.253775738,-0.112017167,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,95577,DB00381,10018838,60,29300,38,22849,0.359287577,1.231303936,0.806417377,1.900988397,0.529068569,DB0038110018838_,0.636637236,0.208073718,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,amlodipine,DB00381
,95579,DB00678,10018838,33,15566,18,10706,0.477616827,1.260920607,0.689237598,2.379784,0.642929916,DB0067810018838_,0.441719556,0.231842095,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,losartan,DB00678
,95583,DB00586,10018884,41,7068,20,2785,0.475766524,0.80775069,0.461577432,1.45808117,0.641329886,DB0058610018884_,0.444211312,-0.21350182,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,diclofenac,DB00586
,95584,DB00678,10018884,210,15389,124,10600,0.179141609,1.166485309,0.928520097,1.470567445,0.32281517,DB0067810018884_,1.130675349,0.153995218,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,losartan,DB00678
,95585,DB01039,10018884,36,2937,31,3020,0.539363739,1.194071628,0.715969689,2.002072995,0.695210901,DB0103910018884_,0.363540025,0.177369004,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,fenofibrate,DB01039
,95586,DB01060,10018884,65,8522,39,5042,1,0.986071668,0.651940395,1.508997042,1,DB0106010018884_,0,-0.014026242,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,amoxicillin,DB01060
,95587,DB01225,10018884,84,4960,105,4535,0.039262991,0.731479497,0.540796792,0.986893764,0.104161053,DB0122510018884_,2.261816994,-0.312686087,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,enoxaparin,DB01225
,95625,DB00482,10003549,142,8117,56,3015,0.687555919,0.94187337,0.684580726,1.311164442,0.811681829,DB0048210003549_,0.208646852,-0.05988444,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,95626,DB00564,10003549,52,2552,34,1429,0.496899783,0.856438455,0.542449796,1.367949534,0.659047875,DB0056410003549_,0.416959099,-0.15497282,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,carbamazepine,DB00564
,95627,DB00734,10003549,62,3988,27,4875,4.61091071245823e-06,2.806724898,1.755664651,4.597317688,5.51400309722314e-05,DB0073410003549_,9.805634591,1.032018287,female,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,95629,DB00916,10003549,103,5220,63,2368,0.075334914,0.741674438,0.534751503,1.035618271,0.170392942,DB0091610003549_,1.769648086,-0.298844895,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,95632,DB01190,10003549,64,4870,50,2235,0.00598413,0.587473408,0.398004309,0.87135328,0.023615774,DB0119010003549_,3.745840409,-0.531924297,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,clindamycin,DB01190
,95634,DB00564,10003988,36,2568,14,1449,0.299249803,1.450809193,0.760599949,2.922071784,0.465251889,DB0056410003988_,0.765176323,0.372121465,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,carbamazepine,DB00564
,95635,DB00868,10003988,66,2918,30,1616,0.391197687,1.218275676,0.776297565,1.952219889,0.561064616,DB0086810003988_,0.577919201,0.197436479,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,benzonatate,DB00868
,95639,DB11133,10003988,57,2374,27,1547,0.214010655,1.375584193,0.851587542,2.272920427,0.366242104,DB1113310003988_,1.004460677,0.318878508,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,omega-3 fatty acids,DB11133
,95668,DB00196,10016256,331,4752,161,3124,0.002296448,1.351516169,1.109888323,1.651013286,0.010883903,DB0019610016256_,4.520470381,0.30122705,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,95673,DB11133,10016256,198,2233,123,1451,0.721146349,1.046011392,0.822670712,1.333970043,0.835521773,DB1113310016256_,0.179698872,0.044984257,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,95674,DB00196,10017577,42,5041,14,3271,0.02829254,1.946491428,1.040081271,3.865530386,0.080908383,DB0019610017577_,2.514437833,0.666028484,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,95676,DB00564,10017577,62,2542,21,1442,0.04881133,1.674600538,1.001739534,2.905176682,0.122793302,DB0056410017577_,2.097252811,0.515574652,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,carbamazepine,DB00564
,95677,DB00734,10017577,46,4004,49,4853,0.53602128,1.137813541,0.742346553,1.741365379,0.692434911,DB0073410017577_,0.367541037,0.129108474,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,95678,DB00814,10017577,150,8137,42,3373,0.024890266,1.480443692,1.042468716,2.142496204,0.073259129,DB0081410017577_,2.613752407,0.392341835,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,95680,DB00916,10017577,53,5270,25,2406,0.902633656,0.967907084,0.589319806,1.629572393,0.957195726,DB0091610017577_,0.043747388,-0.032619184,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,95683,DB01060,10017577,55,8532,40,5041,0.338187539,0.812420348,0.530026556,1.255003188,0.507257274,DB0106010017577_,0.678736959,-0.207737403,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,95685,DB11133,10017577,44,2387,25,1549,0.621688257,1.142117248,0.680595154,1.955790854,0.761946044,DB1113310017577_,0.271879534,0.132883775,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,95687,DB00334,10019211,68,2781,32,2780,0.000373845,2.123953424,1.370877224,3.353203294,0.002423909,DB0033410019211_,6.022373564,0.753279175,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,olanzapine,DB00334
,95689,DB00868,10019211,143,2841,36,1610,6.78354913947493e-06,2.250717357,1.543437626,3.35820015,7.73056965667021e-05,DB0086810019211_,9.467742911,0.811248991,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,benzonatate,DB00868
,95696,DB00316,10024453,78,65396,21,36932,0.001617828,2.097604493,1.281878825,3.57735891,0.008171524,DB0031610024453_,4.807099891,0.740795976,NA,10024453,Ligament sprain,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,95698,DB00338,10024453,43,33631,8,22264,0.000274303,3.558208164,1.653318841,8.76432212,0.001876153,DB0033810024453_,6.278531845,1.269257094,female,10024453,Ligament sprain,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,95720,DB00196,10028334,76,5007,31,3254,0.028485062,1.59319396,1.033769544,2.509683543,0.08134831,DB0019610028334_,2.509015221,0.465740781,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,fluconazole,DB00196
,95723,DB00482,10028334,107,8152,30,3041,0.176951373,1.330441131,0.878230765,2.071500019,0.319975704,DB0048210028334_,1.139510211,0.285510564,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,95724,DB00555,10028334,66,6981,22,3464,0.112030455,1.48855965,0.904914124,2.538008969,0.229125467,DB0055510028334_,1.473485535,0.397808975,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,lamotrigine,DB00555
,95725,DB00586,10028334,127,6982,40,2765,0.225719218,1.257310971,0.872341424,1.84696447,0.380544462,DB0058610028334_,0.966152256,0.228975291,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,95726,DB00697,10028334,167,5929,45,1761,0.619172084,1.102240521,0.78509108,1.575040006,0.759996182,DB0069710028334_,0.27444187,0.097344945,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,tizanidine,DB00697
,95728,DB00814,10028334,129,8158,51,3364,0.868822577,1.042994548,0.746659251,1.476057909,0.94160196,DB0081410028334_,0.060172642,0.042095949,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,95729,DB00868,10028334,38,2946,18,1628,0.674355088,1.166571199,0.647219122,2.178968727,0.802491104,DB0086810028334_,0.22003451,0.154068847,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,benzonatate,DB00868
,95733,DB01060,10028334,107,8480,62,5019,0.936267321,1.021440573,0.738645009,1.422995213,0.976404473,DB0106010028334_,0.02387836,0.021213957,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,amoxicillin,DB01060
,95735,DB11133,10028334,43,2388,29,1545,0.903295089,0.95936231,0.582505349,1.600715922,0.957348417,DB1113310028334_,0.043587882,-0.041486476,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,omega-3 fatty acids,DB11133
,95737,DB00193,10028411,212,19108,66,8636,0.007526422,1.451742897,1.095041042,1.946313175,0.02836876,DB0019310028411_,3.562466732,0.372764833,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,95738,DB00273,10028411,92,8389,15,2178,0.116815703,1.59228983,0.914652478,2.966138828,0.23632871,DB0027310028411_,1.442531604,0.465173125,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,topiramate,DB00273
,95743,DB00814,10028411,94,8193,33,3382,0.492142172,1.175806068,0.781474327,1.809099561,0.65508467,DB0081410028411_,0.422990784,0.161953928,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,95749,DB01015,10028411,92,9795,54,9327,0.004645278,1.622253785,1.14547374,2.316987212,0.019269903,DB0101510028411_,3.949210835,0.483816408,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfamethoxazole,DB01015
,95751,DB11133,10028411,39,2392,17,1557,0.214542966,1.493143534,0.821675041,2.825389357,0.366948326,DB1113310028411_,1.002534242,0.400883652,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,omega-3 fatty acids,DB11133
,95780,DB00186,10028836,102,16799,24,9984,1.16384592271582e-05,2.525783998,1.605289339,4.124859713,0.000123953,DB0018610028836_,8.995605165,0.926551509,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,95781,DB00273,10028836,51,8430,14,2179,0.877491142,0.94160929,0.512204716,1.845667965,0.947981122,DB0027310028836_,0.053420691,-0.060164857,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,topiramate,DB00273
,95782,DB00281,10028836,57,11401,17,5654,0.064241796,1.662750292,0.95248078,3.052142527,0.151070956,DB0028110028836_,1.890005645,0.508473034,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lidocaine,DB00281
,95785,DB00476,10028836,115,17142,28,6149,0.070257499,1.473201534,0.966706895,2.316058263,0.161730381,DB0047610028836_,1.821824642,0.387437947,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,95786,DB00482,10028836,55,8204,20,3051,1,1.022710611,0.602059693,1.804596041,1,DB0048210028836_,0,0.022456565,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,95787,DB00555,10028836,41,7006,10,3476,0.051166331,2.034079895,1.000501672,4.559504137,0.12723211,DB0055510028836_,2.061742227,0.710043577,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lamotrigine,DB00555
,95789,DB00697,10028836,86,6010,12,1794,0.010612681,2.138998986,1.160396946,4.310588677,0.0373208,DB0069710028836_,3.288204459,0.760337956,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tizanidine,DB00697
,95791,DB00814,10028836,73,8214,20,3395,0.109469259,1.508605804,0.907939939,2.617053071,0.225280835,DB0081410028836_,1.490407498,0.411185916,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,95794,DB00924,10028836,93,10069,23,4228,0.02402388,1.69781195,1.064610149,2.813159683,0.071283818,DB0092410028836_,2.64108594,0.529340334,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,95797,DB01015,10028836,42,9845,19,9362,0.006718994,2.101991092,1.194903449,3.829763068,0.025929931,DB0101510028836_,3.652357323,0.742885035,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfamethoxazole,DB01015
,95798,DB01060,10028836,41,8546,11,5070,0.020454731,2.21112527,1.114905339,4.774902307,0.062896314,DB0106010028836_,2.766267722,0.793501558,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,amoxicillin,DB01060
,95800,DB11089,10028836,56,10119,29,8378,0.048679565,1.598752126,1.002615502,2.599395493,0.122575298,DB1108910028836_,2.099029756,0.469223403,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,95802,DB13961,10028836,54,9403,22,6392,0.046028499,1.668504758,0.998106185,2.880151744,0.117536983,DB1396110028836_,2.141002246,0.511927871,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,95808,DB00196,10033425,105,4978,22,3263,1.08328548728666e-07,3.128065729,1.956707674,5.215073229,1.95162159241465e-06,DB0019610033425_,13.14684995,1.140414836,female,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,fluconazole,DB00196
,95811,DB00734,10033425,41,4009,21,4881,0.001197209,2.376830549,1.369831973,4.241334872,0.006396717,DB0073410033425_,5.051970435,0.865767898,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,risperidone,DB00734
,95812,DB00868,10033425,72,2912,21,1625,0.008350466,1.91302387,1.15783109,3.288458014,0.030808055,DB0086810033425_,3.479979094,0.648685168,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,benzonatate,DB00868
,95816,DB01060,10033425,136,8451,63,5018,0.120513963,1.281780896,0.941933667,1.760280924,0.242105589,DB0106010033425_,1.418381331,0.248250436,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,amoxicillin,DB01060
,95817,DB01190,10033425,47,4887,23,2262,0.797822806,0.945853851,0.561341181,1.636294688,0.890762343,DB0119010033425_,0.115677618,-0.055667214,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,clindamycin,DB01190
,95818,DB11133,10033425,83,2348,37,1537,0.057719795,1.468290745,0.979508537,2.238087059,0.139183049,DB1113310033425_,1.971965315,0.384098966,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,omega-3 fatty acids,DB11133
,95819,DB00186,10039203,42,16859,25,9983,1,0.994805876,0.591959468,1.704256412,1,DB0018610039203_,0,-0.005207661,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,95820,DB00193,10039203,72,19248,30,8672,0.830294686,1.081292475,0.69661739,1.716617066,0.910996841,DB0019310039203_,0.093215849,0.078157062,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,95824,DB00338,10039203,103,33571,34,22238,0.000306881,2.006703646,1.349451568,3.05191752,0.002055127,DB0033810039203_,6.187417401,0.696493399,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,95826,DB00476,10039203,65,17192,21,6156,0.806288299,1.108316796,0.668059669,1.9105849,0.895289285,DB0047610039203_,0.11060839,0.102842465,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,95835,DB00924,10039203,55,10107,21,4230,0.801410556,1.096120085,0.651298891,1.910754961,0.892535197,DB0092410039203_,0.11368933,0.091776749,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,95840,DB01068,10039203,58,13705,24,6816,0.482956163,1.201864929,0.734406991,2.024566615,0.647177153,DB0106810039203_,0.435135215,0.183874458,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,95847,DB00193,10047571,130,19190,29,8673,0.000289896,2.025957226,1.345111486,3.146377104,0.001961619,DB0019310047571_,6.233985233,0.706042293,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,tramadol,DB00193
,95849,DB00273,10047571,83,8398,16,2177,0.318408702,1.344706159,0.77923531,2.466183331,0.486379353,DB0027310047571_,0.720766397,0.29617552,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,topiramate,DB00273
,95852,DB00697,10047571,76,6020,13,1793,0.074461463,1.74106239,0.956939571,3.427361578,0.168941308,DB0069710047571_,1.778203913,0.554495496,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,tizanidine,DB00697
,95853,DB00814,10047571,77,8210,21,3394,0.094798595,1.515783505,0.923870302,2.59072121,0.20293005,DB0081410047571_,1.59489394,0.41593247,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,meloxicam,DB00814
,95857,DB00924,10047571,78,10084,13,4238,0.001102519,2.521475841,1.390041526,4.951351769,0.005965356,DB0092410047571_,5.121786518,0.924844381,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,cyclobenzaprine,DB00924
,95860,DB01060,10047571,39,8548,17,5064,0.333341971,1.359050192,0.750087871,2.564920837,0.502373356,DB0106010047571_,0.688411699,0.306786068,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,amoxicillin,DB01060
,95861,DB01068,10047571,111,13652,29,6811,0.001523373,1.909534104,1.257781348,2.984767228,0.007791621,DB0106810047571_,4.854706324,0.646859287,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,clonazepam,DB01068
,95892,DB00814,10047899,135,8152,50,3365,0.568450638,1.114498941,0.797902529,1.57832258,0.719493669,DB0081410047899_,0.329207552,0.108404923,NA,10047899,Weight increased,10022891,Investigations,Inv,meloxicam,DB00814
,95893,DB00868,10047899,42,2942,18,1628,0.416732997,1.291134775,0.724504607,2.391157167,0.585938476,DB0086810047899_,0.534540485,0.255521502,NA,10047899,Weight increased,10022891,Investigations,Inv,benzonatate,DB00868
,95895,DB00916,10047899,38,5285,15,2416,0.766535594,1.158065207,0.62093745,2.270790372,0.871507768,DB0091610047899_,0.1375305,0.146750687,NA,10047899,Weight increased,10022891,Investigations,Inv,metronidazole,DB00916
,95898,DB01015,10047899,103,9784,79,9302,0.157432731,1.23955132,0.914322917,1.685881858,0.294104734,DB0101510047899_,1.223819338,0.214749475,NA,10047899,Weight increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,95899,DB01060,10047899,88,8499,55,5026,0.794230119,0.946186161,0.666669672,1.353038159,0.888516684,DB0106010047899_,0.118201854,-0.055315941,NA,10047899,Weight increased,10022891,Investigations,Inv,amoxicillin,DB01060
,95900,DB01190,10047899,47,4887,9,2276,0.013340095,2.431875572,1.175572783,5.654049407,0.04479075,DB0119010047899_,3.105753625,0.8886628,NA,10047899,Weight increased,10022891,Investigations,Inv,clindamycin,DB01190
,95901,DB11089,10047899,190,9985,93,8314,2.32314814648373e-05,1.701059312,1.318122038,2.207924433,0.000227004,DB1108910047899_,8.390544999,0.531251182,NA,10047899,Weight increased,10022891,Investigations,Inv,docusate,DB11089
,95902,DB11133,10047899,50,2381,20,1554,0.065087768,1.631478269,0.949563017,2.905078428,0.152582562,DB1113310047899_,1.880049436,0.489486517,NA,10047899,Weight increased,10022891,Investigations,Inv,omega-3 fatty acids,DB11133
,95904,DB00196,10048959,62,5021,19,3266,0.002892369,2.12240098,1.249621848,3.766251642,0.013118094,DB0019610048959_,4.333762812,0.752547985,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,95908,DB00814,10048959,185,8102,60,3355,0.117902689,1.276739973,0.946554366,1.743257651,0.238040051,DB0081410048959_,1.435316339,0.244309933,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,95912,DB01060,10048959,106,8481,67,5014,0.692455065,0.935342747,0.680942578,1.292432886,0.814716831,DB0106010048959_,0.204914672,-0.066842242,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,95913,DB11089,10048959,209,9966,156,8251,0.339559018,1.109157618,0.895205146,1.376584047,0.508641491,DB1108910048959_,0.676011851,0.103600824,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,95919,DB00316,10050031,53,65421,31,36922,0.909639502,0.964869671,0.607989861,1.555341558,0.959437782,DB0031610050031_,0.04140781,-0.035762243,NA,10050031,Muscle strain,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,95921,DB00338,10050031,34,33640,18,22254,0.481418718,1.249544887,0.685980786,2.350575338,0.646045387,DB0033810050031_,0.436885519,0.222779395,NA,10050031,Muscle strain,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,95946,DB00186,10052904,90,16811,23,9985,0.000128699,2.324108438,1.455881233,3.853713054,0.000988992,DB0018610052904_,6.918824697,0.843336498,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,95947,DB00193,10052904,147,19173,47,8655,0.042669592,1.411894158,1.009201941,2.007008738,0.111052054,DB0019310052904_,2.197756234,0.344932177,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,95949,DB00281,10052904,60,11398,16,5655,0.027339364,1.860463614,1.056778899,3.463823947,0.078730779,DB0028110052904_,2.541721104,0.620825711,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,lidocaine,DB00281
,95951,DB00482,10052904,109,8150,23,3048,0.010383435,1.772342031,1.120035753,2.918558052,0.036681486,DB0048210052904_,3.30548311,0.572301853,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,95952,DB00555,10052904,51,6996,11,3475,0.009646286,2.3027851,1.183327419,4.906815936,0.034581647,DB0055510052904_,3.364432166,0.834119304,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,lamotrigine,DB00555
,95954,DB00586,10052904,79,7030,23,2782,0.224355369,1.359175761,0.843204631,2.271563876,0.378971845,DB0058610052904_,0.970293363,0.306878458,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,95955,DB00697,10052904,68,6028,28,1778,0.142717889,0.716356997,0.453423283,1.159506905,0.273630293,DB0069710052904_,1.29597738,-0.333576638,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,tizanidine,DB00697
,95960,DB01015,10052904,41,9846,18,9363,0.005799189,2.165849109,1.215819566,4.008845997,0.023043497,DB0101510052904_,3.770371675,0.772812483,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfamethoxazole,DB01015
,95961,DB01060,10052904,40,8547,29,5052,0.453841791,0.815311464,0.492310692,1.365394452,0.621411235,DB0106010052904_,0.475762202,-0.204185075,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,amoxicillin,DB01060
,96057,DB00186,10061822,113,16788,48,9960,0.059631824,1.396665388,0.987067147,2.002702113,0.142785015,DB0018610061822_,1.946415173,0.33408753,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,96058,DB00193,10061822,144,19176,51,8651,0.140936264,1.273753896,0.918555536,1.791303682,0.271193975,DB0019310061822_,1.304920939,0.241968364,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,96060,DB00281,10061822,40,11418,13,5658,0.241582758,1.524683261,0.798079582,3.109561078,0.399665446,DB0028110061822_,0.917127466,0.421786691,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,96062,DB00404,10061822,137,19755,47,9815,0.027845666,1.448207862,1.031742382,2.064491955,0.079876095,DB0040410061822_,2.527278658,0.370326834,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,96064,DB00476,10061822,113,17144,39,6138,0.926450044,1.037381355,0.714111214,1.535612237,0.968741498,DB0047610061822_,0.031757475,0.03669961,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,96065,DB00555,10061822,54,6993,9,3477,0.001090873,2.983022189,1.458484884,6.880857597,0.005916877,DB0055510061822_,5.129946578,1.092936944,female,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,96067,DB00697,10061822,44,6052,10,1796,0.518084627,1.3057004,0.645774862,2.915561122,0.677438866,DB0069710061822_,0.389435965,0.266739602,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,96071,DB00924,10061822,64,10098,18,4233,0.145857799,1.490463726,0.871090758,2.675620613,0.278250336,DB0092410061822_,1.279234083,0.399087297,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,96074,DB01015,10061822,74,9813,44,9337,0.015963162,1.60019217,1.086039778,2.382434471,0.051740761,DB0101510061822_,2.961509395,0.470123728,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,96075,DB01060,10061822,47,8540,20,5061,0.254180893,1.392631566,0.808212329,2.484109019,0.414797589,DB0106010061822_,0.879964614,0.33119517,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,96076,DB01068,10061822,80,13683,22,6818,0.011358492,1.811889455,1.117577981,3.054257101,0.039400589,DB0106810061822_,3.233974504,0.594370199,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,96078,DB11089,10061822,77,10098,52,8355,0.287007334,1.225161798,0.849628241,1.779068675,0.451814685,DB1108910061822_,0.794483173,0.203072915,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,96080,DB13961,10061822,51,9406,34,6380,1,1.017435369,0.645727865,1.621506013,1,DB1396110061822_,0,0.017285117,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,96117,DB00275,10003239,60,2000,23,1214,0.066350769,1.583270594,0.958579868,2.697977685,0.154797848,DB0027510003239_,1.865635217,0.459492704,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,olmesartan,DB00275
,96119,DB01216,10003239,11,225,157,6958,0.023031242,2.166217472,1.044573363,4.058763182,0.06897302,DB0121610003239_,2.674039871,0.772982546,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,finasteride,DB01216
,96121,DB00190,10013573,205,3092,248,4426,0.085692526,1.183212551,0.972804708,1.43786428,0.187827555,DB0019010013573_,1.672230998,0.16823324,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,96124,DB00275,10019211,108,1952,33,1204,0.000346469,2.018234763,1.345462953,3.098993295,0.002276449,DB0027510019211_,6.085138667,0.70222325,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,olmesartan,DB00275
,96126,DB01039,10019211,163,2810,69,2982,7.04026150395681e-11,2.506559076,1.870898321,3.388193029,2.35886900741242e-09,DB0103910019211_,19.86508357,0.918910927,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,fenofibrate,DB01039
,96127,DB09539,10019211,48,619,29,651,0.02524493,1.740016473,1.059738348,2.901241326,0.074041842,DB0953910019211_,2.603124911,0.55389458,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,omega-3-acid ethyl esters,DB09539
,96129,DB00126,10044565,113,10058,53,5892,0.196196541,1.248985658,0.89201747,1.768183016,0.344459965,DB0012610044565_,1.065777408,0.222331748,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,96130,DB00190,10044565,153,3144,177,4497,0.06759199,1.236355555,0.984370233,1.551518912,0.157017716,DB0019010044565_,1.851396637,0.212167983,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,96133,DB01039,10044565,34,2939,26,3025,0.299389925,1.345885991,0.781886318,2.341876991,0.465414684,DB0103910044565_,0.764826478,0.297052525,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,fenofibrate,DB01039
,96144,DB14513,10064355,36,7141,16,3548,0.769595664,1.117894069,0.603781787,2.160730876,0.873834079,DB1451310064355_,0.134864762,0.11144662,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium,DB14513
,96145,DB00959,10001497,21,8057,36,4966,0.000171663,0.359570687,0.199202153,0.633621191,0.001267994,DB0095910001497_,6.670319096,-1.022844496,male,10001497,Agitation,10037175,Psychiatric disorders,Psych,methylprednisolone,DB00959
,96154,DB00196,10046735,51,5032,18,3267,0.025649209,1.839399875,1.054327908,3.351709789,0.074930755,DB0019610046735_,2.591190862,0.609439363,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,fluconazole,DB00196
,96158,DB00005,10012267,50,128032,20,42399,0.489560789,0.827877273,0.483995529,1.468351698,0.652924232,DB0000510012267_,0.426294188,-0.188890356,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,96173,DB01217,10011906,121,2633,7,261,0.20322004,1.713221208,0.794820036,4.397730074,0.352897879,DB0121710011906_,1.041576558,0.538375346,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,anastrozole,DB01217
,96175,DB00537,10006784,45,7512,21,4277,0.521565621,1.219984334,0.710716274,2.159307262,0.680347999,DB0053710006784_,0.385150848,0.198838018,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,96178,DB00537,10028372,71,7486,36,4262,0.614449938,1.12285089,0.740329542,1.729799099,0.755912039,DB0053710028372_,0.279830261,0.115870889,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,ciprofloxacin,DB00537
,96181,DB00537,10044565,65,7492,26,4272,0.154263617,1.425479989,0.890305926,2.344706435,0.289868048,DB0053710044565_,1.238329468,0.354508591,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,96182,DB00537,10047571,46,7511,17,4281,0.148149973,1.542202618,0.866149502,2.873211957,0.281428202,DB0053710047571_,1.267877919,0.433211666,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,ciprofloxacin,DB00537
,96183,DB01050,10047571,120,17988,35,9336,0.002138868,1.779437787,1.211065449,2.675283202,0.010279382,DB0105010047571_,4.577615123,0.576297464,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,ibuprofen,DB01050
,96197,DB01222,10028391,41,9233,16,5389,0.215156262,1.49560842,0.820324718,2.857996144,0.367590663,DB0122210028391_,1.00078529,0.402533094,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,budesonide,DB01222
,96200,DB00264,10069326,121,29486,46,24846,1.688081532178e-06,2.216417042,1.565528602,3.185742927,2.28599809754244e-05,DB0026410069326_,10.68612273,0.795891947,NA,10069326,Product substitution issue,10077536,Product issues,Prod,metoprolol,DB00264
,96208,DB00285,10042609,46,10905,10,3708,0.22087726,1.564030945,0.777585573,3.479703203,0.374555751,DB0028510042609_,0.982014619,0.447266428,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,venlafaxine,DB00285
,96211,DB00285,10047899,218,10733,55,3663,0.049056092,1.352675297,0.999604196,1.857500628,0.123202691,DB0028510047899_,2.093924382,0.302084333,NA,10047899,Weight increased,10022891,Investigations,Inv,venlafaxine,DB00285
,96214,DB00829,10045555,36,8016,28,4426,0.190837126,0.709949554,0.420619654,1.209542109,0.337606263,DB0082910045555_,1.085874964,-0.342561363,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,96223,DB00788,10010264,205,9151,65,4996,0.00010493,1.721786147,1.293662105,2.31770054,0.000831497,DB0078810010264_,7.092283027,0.543362209,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,96224,DB08868,10010264,58,9144,23,2488,0.134772283,0.686167392,0.415764297,1.168061997,0.262299763,DB0886810010264_,1.338267296,-0.376633669,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,96227,DB08868,10025415,141,9061,52,2459,0.063409354,0.735886256,0.530059146,1.035217471,0.149648922,DB0886810025415_,1.899463249,-0.306679716,NA,10025415,Macular oedema,10015919,Eye disorders,Eye,fingolimod,DB08868
,96236,DB01156,10022061,91,13531,17,6311,0.00024354,2.496571396,1.475200084,4.47530934,0.001696869,DB0115610022061_,6.37897056,0.914918349,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,96237,DB01156,10022095,86,13536,35,6293,0.557257612,1.142331943,0.761830274,1.746258838,0.710440952,DB0115610022095_,0.341869442,0.133071737,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,96238,DB01156,10053425,52,13570,8,6320,0.001929465,3.027119934,1.42688984,7.383734059,0.009456053,DB0115610053425_,4.661100237,1.107611651,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,96247,DB00820,10069802,43,11872,12,5804,0.085821658,1.75177514,0.906637172,3.652201098,0.18807139,DB0082010069802_,1.670933653,0.560629639,NA,10069802,Device related sepsis,10021881,Infections and infestations,Infec,tadalafil,DB00820
,96248,DB05676,10001760,460,46669,62,25267,1.97731515456356e-33,4.016796988,3.074524752,5.326850187,5.4709188250214e-31,DB0567610001760_,69.68069131,1.390484816,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,96266,DB01373,10013710,65,22655,19,7362,0.799577844,1.111705224,0.657846397,1.964633031,0.891680255,DB0137310013710_,0.114647669,0.105895074,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,96267,DB08815,10019211,47,1407,17,686,0.344236063,1.347807441,0.753039709,2.523427566,0.513550424,DB0881510019211_,0.666407058,0.298479155,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lurasidone,DB08815
,96268,DB09065,10019211,20,732,60,1877,0.614094907,0.854789426,0.484415643,1.450592251,0.755669793,DB0906510019211_,0.28015078,-0.156900125,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cobicistat,DB09065
,96269,DB01238,10020937,49,5201,16,3486,0.010817717,2.052496946,1.145203193,3.873434333,0.037909965,DB0123810020937_,3.272541285,0.719057074,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,96274,DB01373,10028836,135,22585,22,7359,0.001498943,1.999293268,1.266814801,3.299038209,0.007686997,DB0137310028836_,4.868225019,0.692793752,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,96299,DB01238,10070863,102,5148,94,3408,0.022393897,0.718388237,0.535573694,0.964453937,0.067497106,DB0123810070863_,2.695670557,-0.330745135,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole,DB01238
,96300,DB08815,10070863,47,1407,35,668,0.05429521,0.637677217,0.398743172,1.028185329,0.13303035,DB0881510070863_,2.017177978,-0.449923053,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,lurasidone,DB08815
,96308,DB06285,10047895,106,8744,7,1099,0.098685222,1.903149854,0.888994689,4.860948675,0.20886871,DB0628510047895_,1.566049406,0.643510331,NA,10047895,Weight decreased,10022891,Investigations,Inv,teriparatide,DB06285
,96312,DB01261,10013573,150,3631,106,3197,0.096996306,1.245913344,0.960502251,1.620816677,0.206274126,DB0126110013573_,1.578549286,0.21986887,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sitagliptin,DB01261
,96313,DB01261,10016173,93,3688,76,3227,0.696708875,1.070737781,0.77918334,1.475083183,0.817528949,DB0126110016173_,0.201468965,0.068347926,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sitagliptin,DB01261
,96314,DB01261,10021789,34,3747,25,3278,0.600562415,1.189743352,0.687600574,2.084899182,0.744911076,DB0126110021789_,0.294490429,0.173737613,NA,10021789,Infection,10021881,Infections and infestations,Infec,sitagliptin,DB01261
,96315,DB01261,10025482,98,3683,61,3242,0.036573242,1.414117492,1.013080509,1.987242777,0.098714142,DB0126110025482_,2.31552706,0.346505656,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,96316,DB00331,10041466,72,24874,45,20707,0.137554414,1.331950928,0.904813473,1.979292311,0.266287989,DB0033110041466_,1.323176891,0.286644731,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,metformin,DB00331
,96317,DB00331,10061599,37,24909,15,20737,0.017511406,2.053458247,1.099734297,4.028794583,0.055691053,DB0033110061599_,2.887935776,0.719525322,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,96319,DB00535,10013700,98,1106,27,619,0.00093467,2.03071146,1.297913342,3.272825483,0.005208905,DB0053510013700_,5.257385533,0.708386205,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,cefdinir,DB00535
,96320,DB00535,10013968,58,1146,16,630,0.017408638,1.992139208,1.118410498,3.745189937,0.055424667,DB0053510013968_,2.892730523,0.68920904,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cefdinir,DB00535
,96329,DB00193,10005724,86,19234,24,8678,0.038586271,1.616703895,1.017507625,2.660505979,0.102802933,DB0019310005724_,2.274941398,0.480389444,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,tramadol,DB00193
,96333,DB00927,10005724,47,7450,16,5000,0.019696291,1.971371728,1.096298822,3.728962823,0.061066924,DB0092710005724_,2.795784898,0.678729609,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,famotidine,DB00927
,96335,DB01377,10005724,45,3751,14,2656,0.005229314,2.275686688,1.223660724,4.498697978,0.021210171,DB0137710005724_,3.853274454,0.822281848,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,magnesium oxide,DB01377
,96336,DB09140,10005724,44,3697,9,1789,0.017425318,2.365455726,1.136429206,5.523495891,0.055457619,DB0914010005724_,2.892136173,0.860970699,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,oxygen,DB09140
,96338,DB00203,10005802,38,13840,12,8926,0.029336284,2.04225302,1.044041682,4.295273378,0.083241132,DB0020310005802_,2.486013674,0.71405362,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,sildenafil,DB00203
,96339,DB00421,10005802,39,8864,12,5240,0.057859793,1.921172321,0.98443185,4.034443468,0.139437486,DB0042110005802_,1.97013891,0.652935584,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,spironolactone,DB00421
,96348,DB00091,10007882,46,5464,21,2649,0.896304927,1.061955496,0.619564951,1.877505285,0.956301489,DB0009110007882_,0.044682051,0.060112016,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,cyclosporine,DB00091
,96349,DB00688,10007882,28,6462,40,5338,0.027700695,0.578276815,0.343079865,0.962400658,0.079570818,DB0068810007882_,2.531107861,-0.547702606,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,96351,DB01377,10007882,46,3750,22,2648,0.139116819,1.476373908,0.867840279,2.5836395,0.26857469,DB0137710007882_,1.314626228,0.389589019,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,magnesium oxide,DB01377
,96352,DB09140,10007882,72,3669,21,1777,0.044015028,1.660415766,1.005515416,2.852874812,0.113622553,DB0914010007882_,2.174873267,0.507068032,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,oxygen,DB09140
,96353,DB00091,10015150,80,5430,21,2649,0.010163931,1.858333491,1.134702308,3.172305382,0.036027096,DB0009110015150_,3.323483956,0.619680114,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,cyclosporine,DB00091
,96354,DB00203,10015150,148,13730,75,8863,0.097887356,1.273803921,0.957166796,1.707274427,0.207710619,DB0020310015150_,1.571609421,0.242007637,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,sildenafil,DB00203
,96356,DB00557,10015150,60,5927,19,3048,0.07288894,1.623888968,0.953687897,2.886933705,0.166345629,DB0055710015150_,1.793687553,0.48482387,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxyzine,DB00557
,96357,DB00688,10015150,39,6451,29,5349,0.714730721,1.11505752,0.671039448,1.872439214,0.830887691,DB0068810015150_,0.185260642,0.108905991,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,mycophenolate mofetil,DB00688
,96359,DB09140,10015150,65,3676,16,1782,0.016181819,1.969151768,1.122411691,3.657393145,0.052294012,DB0914010015150_,2.950873408,0.677602875,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,oxygen,DB09140
,96365,DB00682,10016326,39,19420,24,16340,0.255365177,1.367261904,0.801451798,2.377874601,0.416091965,DB0068210016326_,0.876848974,0.31281013,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,96368,DB00996,10016326,66,38887,18,22407,0.004283139,2.112736665,1.239053074,3.782685503,0.018057953,DB0099610016326_,4.014169107,0.747984105,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,96378,DB00927,10016334,37,7460,14,5002,0.084737917,1.771981214,0.934504196,3.552183838,0.186318824,DB0092710016334_,1.680295967,0.572098251,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,96381,DB06403,10016334,77,21394,21,6640,0.720916135,1.138007315,0.694340052,1.943343207,0.835410838,DB0640310016334_,0.179831654,0.129278764,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,96384,DB00193,10018838,31,19289,20,8682,0.225908278,0.697657899,0.384936788,1.292258515,0.380799633,DB0019310018838_,0.96548194,-0.360026413,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,tramadol,DB00193
,96385,DB00203,10018838,60,13818,32,8906,0.453952084,1.208437648,0.773580375,1.920083348,0.62149483,DB0020310018838_,0.475627686,0.189328325,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,sildenafil,DB00203
,96403,DB00557,10018884,32,5955,33,3034,0.005395048,0.494076808,0.293542535,0.83074881,0.021729824,DB0055710018884_,3.829069574,-0.705064292,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,hydroxyzine,DB00557
,96405,DB09140,10018884,109,3632,31,1767,0.007876982,1.710477899,1.133435273,2.649278,0.02941419,DB0914010018884_,3.526278083,0.536772804,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,oxygen,DB09140
,96407,DB00374,10028372,98,17618,17,5707,0.016175711,1.867228233,1.107550348,3.337608234,0.052281409,DB0037410028372_,2.951114441,0.624455103,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,96409,DB00688,10028372,39,6451,31,5347,0.904560126,1.042768325,0.633040612,1.731095462,0.957573483,DB0068810028372_,0.043352816,0.041879027,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,mycophenolate mofetil,DB00688
,96410,DB00761,10028372,146,15161,86,8539,0.731809637,0.956182782,0.726544608,1.264808905,0.844114034,DB0076110028372_,0.169467683,-0.04480619,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,96412,DB01377,10028372,41,3755,24,2646,0.527720116,1.203748713,0.708327548,2.088227922,0.685234831,DB0137710028372_,0.377993681,0.185440615,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium oxide,DB01377
,96413,DB06403,10028372,100,21371,29,6632,0.835651166,1.070082216,0.700943871,1.680300267,0.914888097,DB0640310028372_,0.088953519,0.067735483,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,96414,DB09140,10028372,43,3698,21,1777,1,0.983936587,0.569223064,1.751024599,1,DB0914010028372_,0,-0.016193828,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,oxygen,DB09140
,96415,DB00443,10028813,157,1989,56,1134,0.003044794,1.598205034,1.159865082,2.228617532,0.013683095,DB0044310028813_,4.291594168,0.468881146,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,betamethasone,DB00443
,96417,DB00193,10037400,63,19257,18,8684,0.092575233,1.578311706,0.922056153,2.834220729,0.199356055,DB0019310037400_,1.61266283,0.456355735,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,96422,DB11089,10037400,62,10113,24,8383,0.001069817,2.14128509,1.315952984,3.590862973,0.005820768,DB1108910037400_,5.146323127,0.761406158,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,96423,DB00443,10037660,37,2109,14,1176,0.241079462,1.473523074,0.77427749,2.963371256,0.399217139,DB0044310037660_,0.918249801,0.387656182,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,betamethasone,DB00443
,96424,DB09140,10037660,169,3572,77,1721,0.727917096,1.057456284,0.797730887,1.412025817,0.841246081,DB0914010037660_,0.172871057,0.055866292,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,96425,DB00203,10038153,41,13837,34,8904,0.287451713,0.775995712,0.480084004,1.26171532,0.452353966,DB0020310038153_,0.793290296,-0.253608285,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,sildenafil,DB00203
,96431,DB06403,10038153,57,21414,20,6641,0.594227953,0.883841539,0.522537397,1.55440076,0.740162623,DB0640310038153_,0.300885356,-0.123477487,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,ambrisentan,DB06403
,96433,DB00443,10047700,50,2096,26,1164,0.903667406,1.067953616,0.648287059,1.797515239,0.957417047,DB0044310047700_,0.043516196,0.065744309,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,betamethasone,DB00443
,96434,DB01212,10047700,71,1948,37,1904,0.002338158,1.87527596,1.236361604,2.885940898,0.011050129,DB0121210047700_,4.505313219,0.628755827,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ceftriaxone,DB01212
,96436,DB00688,10047899,79,6411,48,5330,0.089297631,1.368280994,0.942129546,2.005437445,0.19412689,DB0068810047899_,1.63924326,0.313555203,NA,10047899,Weight increased,10022891,Investigations,Inv,mycophenolate mofetil,DB00688
,96437,DB00761,10047899,335,14972,137,8488,0.001370114,1.386258078,1.130906238,1.70682037,0.007139149,DB0076110047899_,4.942161731,0.326608087,NA,10047899,Weight increased,10022891,Investigations,Inv,potassium chloride,DB00761
,96438,DB00927,10047899,103,7394,38,4978,0.001315011,1.824771422,1.244250761,2.726703565,0.006894399,DB0092710047899_,4.977045985,0.601454731,NA,10047899,Weight increased,10022891,Investigations,Inv,famotidine,DB00927
,96440,DB00091,10048959,79,5431,21,2649,0.013190328,1.834768635,1.119418029,3.134033589,0.044398484,DB0009110048959_,3.114549961,0.606918389,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,96441,DB00443,10048959,42,2104,9,1181,0.007360039,2.618813968,1.250929749,6.140827352,0.027869861,DB0044310048959_,3.580209435,0.962721531,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,betamethasone,DB00443
,96442,DB00557,10048959,92,5895,39,3028,0.352840976,1.211646122,0.822302703,1.815199221,0.522593931,DB0055710048959_,0.648950539,0.191979866,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,96443,DB01377,10048959,64,3732,36,2634,0.306717082,1.254690183,0.818710096,1.949642418,0.47376497,DB0137710048959_,0.747043924,0.226888676,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,96444,DB06403,10048959,1038,20433,312,6349,0.645996687,1.033768834,0.907045046,1.180720783,0.781607075,DB0640310048959_,0.246403126,0.033211187,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,96446,DB00512,10005851,16,4721,36,5062,0.012163505,0.476600366,0.246579384,0.882328023,0.041602827,DB0051210005851_,3.179587154,-0.741076947,NA,10005851,Blood urea increased,10022891,Investigations,Inv,vancomycin,DB00512
,96453,DB00563,10040882,77,46569,44,15304,0.004275849,0.575109951,0.391876616,0.853377071,0.018030112,DB0056310040882_,4.015712054,-0.553194037,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,96454,DB00563,10041591,42,46604,10,15338,0.423357038,1.382249077,0.682272361,3.090119028,0.59219248,DB0056310041591_,0.523923561,0.323711938,NA,10041591,Spinal osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,96460,DB06228,10012378,72,15840,38,16038,0.001081458,1.918371043,1.276776477,2.923483633,0.005875673,DB0622810012378_,5.136934693,0.651476411,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,rivaroxaban,DB06228
,96461,DB01060,10013709,273,8314,169,4912,0.652627987,0.954404847,0.782280674,1.167067579,0.786830849,DB0106010013709_,0.239741985,-0.04666733,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,96468,DB08895,10040831,85,28029,27,6619,0.185347484,0.743437188,0.476795715,1.193754038,0.330657299,DB0889510040831_,1.10667279,-0.296470998,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,96471,DB00047,10049848,36,9249,59,8459,0.00539371,0.558075251,0.357704276,0.85991225,0.021726101,DB0004710049848_,3.829240916,-0.583261468,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,96473,DB00787,10049848,117,16883,84,17164,0.016030531,1.416018705,1.059864926,1.898705419,0.051895131,DB0078710049848_,2.9585303,0.347849205,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,96478,DB00441,10038695,29,2245,39,1855,0.049859254,0.614494373,0.364939024,1.023987861,0.124778682,DB0044110038695_,2.081213652,-0.486955507,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gemcitabine,DB00441
,96499,DB00028,10010305,36,13422,23,5592,0.115907529,0.652131485,0.375601014,1.153815883,0.235036316,DB0002810010305_,1.44801524,-0.427509073,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,human immunoglobulin g,DB00028
,96500,DB00281,10010305,99,11359,70,5601,0.026227857,0.697364009,0.507437533,0.962816895,0.076265194,DB0028110010305_,2.573538619,-0.360447753,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,lidocaine,DB00281
,96501,DB00341,10010305,93,11312,55,5013,0.106850281,0.74933363,0.530290615,1.067625368,0.221407933,DB0034110010305_,1.507748427,-0.288570961,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,cetirizine,DB00341
,96504,DB00281,10049848,60,11398,17,5654,0.039343908,1.75071985,1.006950568,3.20372555,0.104333598,DB0028110049848_,2.26016184,0.560027046,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,96505,DB00555,10049848,83,6964,45,3441,0.63690963,0.911374018,0.625047401,1.343992485,0.774319262,DB0055510049848_,0.255771007,-0.092801908,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,96509,DB00059,10033661,26,801,43,1064,0.457474555,0.803272047,0.46955412,1.350258852,0.624823003,DB0005910033661_,0.470286865,-0.219061834,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,pegaspargase,DB00059
,96510,DB00059,10037660,96,731,114,993,0.375763829,1.143843929,0.847947389,1.540617097,0.54558247,DB0005910037660_,0.605901303,0.134394458,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,pegaspargase,DB00059
,96515,DB00541,10063743,31,3103,45,4252,0.907159713,0.943973416,0.576050444,1.528888959,0.958621165,DB0054110063743_,0.042259314,-0.057657275,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,vincristine,DB00541
,96517,DB00338,10051076,38,33636,40,22232,0.048395673,0.627934629,0.391861344,1.004631984,0.122080641,DB0033810051076_,2.103073464,-0.465319212,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,96520,DB00526,10015150,35,1563,32,1862,0.322225814,1.302875726,0.779411834,2.184728901,0.490599254,DB0052610015150_,0.712127667,0.264573919,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,oxaliplatin,DB00526
,96522,DB06403,10042609,53,21418,18,6643,0.779715544,0.913239921,0.525952657,1.657827168,0.880097182,DB0640310042609_,0.127722943,-0.09075665,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,ambrisentan,DB06403
,96523,DB01068,10005750,127,13636,55,6785,0.429446448,1.148939613,0.829820833,1.608941671,0.597928855,DB0106810005750_,0.514283504,0.138839441,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,clonazepam,DB01068
,96526,DB00635,10009657,86,32967,79,23715,0.133000949,0.783106641,0.569979375,1.07717774,0.259949433,DB0063510009657_,1.347268154,-0.244486397,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,prednisone,DB00635
,96531,DB09033,10009900,98,2526,89,1580,0.01400611,0.688829224,0.507955633,0.935056906,0.046604291,DB0903310009900_,3.066062667,-0.372761899,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,vedolizumab,DB09033
,96534,DB06228,10038980,27,15885,44,16032,0.056771035,0.619327629,0.368596973,1.023152714,0.137367823,DB0622810038980_,1.985093112,-0.479120859,NA,10038980,Retroperitoneal haemorrhage,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,96539,DB00215,10069327,53,11050,19,5257,0.314411185,1.327107065,0.771898535,2.376421259,0.482006172,DB0021510069327_,0.729798359,0.283001434,NA,10069327,Product quality issue,10077536,Product issues,Prod,citalopram,DB00215
,96540,DB00983,10037844,72,3429,31,1709,0.527958732,1.15752077,0.746574042,1.832671344,0.685443898,DB0098310037844_,0.377688624,0.146280451,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,formoterol,DB00983
,96549,DB00421,10001949,35,8868,21,5231,1,0.983117267,0.555925328,1.779326809,1,DB0042110001949_,0,-0.017026871,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,96556,DB00924,10001949,63,10099,23,4228,0.636230761,1.146735723,0.700219038,1.940149707,0.773906548,DB0092410001949_,0.256304152,0.136919405,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,96561,DB05259,10001949,51,11219,8,2720,0.322431948,1.545538083,0.726947505,3.775459794,0.490770962,DB0525910001949_,0.711777732,0.435372124,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,96563,DB08868,10001949,72,9130,24,2487,0.383341718,0.817211034,0.507385213,1.359723466,0.553405853,DB0886810001949_,0.591663636,-0.201857914,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,96567,DB00273,10025482,202,8279,22,2171,2.46431918797484e-05,2.407657244,1.542466242,3.938151572,0.000238581,DB0027310025482_,8.340803406,0.878654177,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,96570,DB00745,10025482,77,2500,23,1060,0.15029605,1.419389723,0.875434615,2.383587031,0.28437458,DB0074510025482_,1.257462966,0.350227007,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,modafinil,DB00745
,96571,DB00887,10025482,102,2239,46,1769,0.0017206,1.75169842,1.217700425,2.552866255,0.008589112,DB0088710025482_,4.757259955,0.560585843,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,96572,DB00972,10025482,80,2424,28,1151,0.175368528,1.356587954,0.866633568,2.180223845,0.317900811,DB0097210025482_,1.14601586,0.30497269,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,azelastine,DB00972
,96574,DB05259,10025482,185,11085,29,2699,0.029251598,1.553190368,1.043408473,2.38927228,0.083054631,DB0525910025482_,2.488256681,0.440311117,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,96575,DB06700,10025482,116,2109,24,594,0.207002965,1.361154426,0.861861637,2.231101151,0.357612418,DB0670010025482_,1.028305509,0.308333182,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,desvenlafaxine,DB06700
,96577,DB11133,10025482,74,2357,31,1543,0.042512778,1.562536425,1.008887095,2.472028454,0.110726157,DB1113310025482_,2.200695184,0.446310414,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,96578,DB00060,10051055,41,9467,17,2448,0.104288472,0.62366867,0.345888424,1.172988178,0.217470442,DB0006010051055_,1.525692335,-0.472136029,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,interferon beta-1a,DB00060
,96593,DB00169,10054889,42,38649,25,18150,0.359904727,0.788976016,0.469644091,1.351248082,0.529680612,DB0016910054889_,0.635481072,-0.237019357,NA,10054889,Transaminases increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,96613,DB00421,10061822,79,8824,36,5216,0.208732102,1.297146281,0.862733808,1.98408876,0.359807411,DB0042110061822_,1.02218636,0.260166683,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,96627,DB01068,10013395,36,13727,36,6804,0.003631659,0.495669311,0.303213018,0.810385054,0.015786035,DB0106810013395_,4.148629592,-0.701846286,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,96642,DB00065,10068319,51,9413,25,4932,0.903693635,1.068870626,0.649255697,1.802706981,0.957417047,DB0006510068319_,0.043516196,0.066602601,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,infliximab,DB00065
,96643,DB00959,10068319,64,8014,13,4989,7.89643929626702e-05,3.064557493,1.669120627,6.072894245,0.000651878,DB0095910068319_,7.335653363,1.119903185,female,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,96644,DB01075,10068319,172,19776,56,11041,0.000380583,1.714759525,1.260277235,2.364170082,0.002460918,DB0107510068319_,6.007220972,0.539272852,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,96647,DB00331,10005003,27,24919,119,20633,4.65193170976793e-19,0.1878938,0.11886194,0.287345919,4.43833121565336e-17,DB0033110005003_,37.65366813,-1.671878367,male,10005003,Bladder cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metformin,DB00331
,96656,DB00512,10048799,49,4688,75,5023,0.057420661,0.700047374,0.477030775,1.019225754,0.138569783,DB0051210048799_,1.976381232,-0.356607268,NA,10048799,Acute generalised exanthematous pustulosis,10040785,Skin and subcutaneous tissue disorders,Skin,vancomycin,DB00512
,96659,DB01067,10070863,41,4320,76,4747,0.006812171,0.592831865,0.394336286,0.880046694,0.026225985,DB0106710070863_,3.641004569,-0.522844453,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,glipizide,DB01067
,96662,DB00688,10020937,36,6454,23,5355,0.360364532,1.298659313,0.747750881,2.298550527,0.530261758,DB0068810020937_,0.634384511,0.261332435,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,mycophenolate mofetil,DB00688
,96667,DB01222,10033775,76,9198,29,5376,0.053580458,1.531685046,0.985137365,2.440860629,0.131714973,DB0122210033775_,2.027114986,0.426368467,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,96669,DB05676,10062519,37,47092,15,25314,0.386445911,1.325950984,0.710192538,2.601067778,0.556587987,DB0567610062519_,0.585930013,0.282129926,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,96673,DB01115,10007559,41,3559,31,2237,0.465913439,0.831337872,0.507095715,1.375467467,0.632699667,DB0111510007559_,0.45775943,-0.184718981,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,nifedipine,DB01115
,96676,DB01016,10033371,41,1060,33,1195,0.157827079,1.400444051,0.856915065,2.304116655,0.294553023,DB0101610033371_,1.222296247,0.336789366,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,glyburide,DB01016
,96678,DB00722,10034474,45,25358,47,25985,1,0.981118427,0.636937116,1.50962578,1,DB0072210034474_,0,-0.019062106,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,lisinopril,DB00722
,96684,DB01115,10037423,37,3563,26,2242,0.697207833,0.895483149,0.526212557,1.544694542,0.817855981,DB0111510037423_,0.20106902,-0.110391875,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nifedipine,DB01115
,96687,DB01065,10000087,71,4260,31,3020,0.025683089,1.623551435,1.047623504,2.569012386,0.074996389,DB0106510000087_,2.59031531,0.484615993,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,melatonin,DB01065
,96689,DB06723,10013573,47,983,17,593,0.085903693,1.667338869,0.929609283,3.127492018,0.188196246,DB0672310013573_,1.670269996,0.511228864,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,aluminum hydroxide,DB06723
,96690,DB09104,10013573,38,1012,17,855,0.038364313,1.887916538,1.03143968,3.594250264,0.102365849,DB0910410013573_,2.279202128,0.63547386,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,magnesium hydroxide,DB09104
,96691,DB00734,10016173,69,3981,74,4828,0.498376873,1.130800369,0.800330554,1.596040305,0.660264011,DB0073410016173_,0.415115508,0.122925673,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,96692,DB01065,10016173,179,4152,134,2917,0.597874474,0.93849606,0.742130594,1.189066593,0.742891677,DB0106510016173_,0.297205036,-0.063476621,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,melatonin,DB01065
,96695,DB09104,10016173,63,987,36,836,0.077639663,1.481968866,0.957895309,2.323090183,0.174349299,DB0910410016173_,1.746694526,0.393371518,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium hydroxide,DB09104
,96696,DB00215,10019303,48,11055,10,5266,0.015890464,2.28636139,1.141014694,5.073004793,0.051571902,DB0021510019303_,2.964778283,0.826961641,NA,10019303,Heart rate increased,10022891,Investigations,Inv,citalopram,DB00215
,96700,DB01075,10019303,124,19824,60,11037,0.396739676,1.150595341,0.838013065,1.594800144,0.566324665,DB0107510019303_,0.568587752,0.140279496,NA,10019303,Heart rate increased,10022891,Investigations,Inv,diphenhydramine,DB01075
,96705,DB00575,10020642,53,5191,49,3780,0.26734207,0.787654567,0.522704565,1.18901157,0.429633548,DB0057510020642_,0.844822647,-0.238695653,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,clonidine,DB00575
,96706,DB00734,10020642,19,4031,31,4871,0.321939484,0.740648557,0.394664179,1.355522458,0.490256747,DB0073410020642_,0.712826052,-0.300229048,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,risperidone,DB00734
,96707,DB01065,10020642,30,4301,26,3025,0.496214281,0.811557748,0.462857441,1.431740145,0.658507258,DB0106510020642_,0.417779735,-0.208799732,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,melatonin,DB01065
,96710,DB01065,10033371,172,4159,66,2985,1.21734366505852e-05,1.870263999,1.394414397,2.533623767,0.000129024,DB0106510033371_,8.95551443,0.626079597,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,96711,DB06723,10033371,39,991,19,591,0.580359505,1.223942888,0.683038436,2.264756559,0.728950619,DB0672310033371_,0.316149287,0.202077523,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,aluminum hydroxide,DB06723
,96712,DB00215,10052904,54,11049,21,5255,0.460627241,1.222955108,0.725635921,2.134283922,0.627974638,DB0021510052904_,0.465255498,0.20127015,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,96713,DB00455,10052904,62,9339,20,5098,0.048009536,1.69218019,1.006840748,2.96159879,0.121368662,DB0045510052904_,2.108922572,0.526017751,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,96716,DB01075,10052904,88,19860,40,11057,0.310223533,1.22479366,0.833088788,1.828723667,0.477637393,DB0107510052904_,0.738903427,0.202772389,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,96727,DB01136,10040560,40,9844,53,11062,0.466952655,0.848105437,0.547583813,1.30429446,0.633505408,DB0113610040560_,0.456486743,-0.164750315,NA,10040560,Shock,10047065,Vascular disorders,Vasc,carvedilol,DB01136
,96735,DB00108,10021097,54,10140,23,3272,0.286782217,0.757619071,0.456334517,1.295573948,0.451570753,DB0010810021097_,0.795023212,-0.277574564,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,natalizumab,DB00108
,96751,DB08908,10065154,62,10611,22,3257,0.6054073,0.865062586,0.523357703,1.480318956,0.748526504,DB0890810065154_,0.289648667,-0.144953421,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,dimethyl fumarate,DB08908
,96777,DB09153,10015090,41,7758,38,5661,0.305001302,0.787326827,0.493205935,1.259665436,0.471780098,DB0915310015090_,0.751242295,-0.239111835,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,96791,DB00563,10013946,172,46474,39,15309,0.037417792,1.452744346,1.020664437,2.114131402,0.100421345,DB0056310013946_,2.298380498,0.37345442,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,96800,DB01075,10010144,1034,18914,553,10544,0.451650985,1.04236086,0.936552447,1.161046326,0.619282532,DB0107510010144_,0.479193677,0.041488198,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,96802,DB08816,10037844,22,1129,44,1858,0.521745814,0.822926956,0.467062505,1.411343608,0.680464857,DB0881610037844_,0.384979102,-0.194887836,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ticagrelor,DB08816
,96806,DB01225,10055798,61,4983,134,4506,4.26006027891252e-09,0.411682166,0.298184111,0.562908658,1.03873739482545e-07,DB0122510055798_,16.08008972,-0.88750367,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,enoxaparin,DB01225
,96814,DB01373,10005956,80,22640,20,7361,0.351443062,1.30050772,0.788281661,2.243388682,0.521152063,DB0137310005956_,0.651713412,0.262754742,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,96824,DB06285,10028813,479,8371,26,1080,2.73929927830791e-06,2.37674312,1.592327031,3.69487816,3.4961146652257e-05,DB0628510028813_,10.26127321,0.865731114,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,teriparatide,DB06285
,96842,DB00295,10017955,38,14625,54,9548,0.000243591,0.459425808,0.29487415,0.709342081,0.001697002,DB0029510017955_,6.378892323,-0.777777813,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,96846,DB00295,10037377,78,14585,71,9531,0.044086513,0.717932686,0.513277906,1.005596698,0.113754505,DB0029510037377_,2.173712616,-0.331379467,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,96850,DB00264,10041660,11,29596,40,24852,3.05631051372704e-06,0.230904669,0.106813146,0.458707806,3.85392764947542e-05,DB0026410041660_,10.16383267,-1.46575034,male,10041660,Splenomegaly,10005329,Blood and lymphatic system disorders,Blood,metoprolol,DB00264
,96868,DB00367,10037844,84,22716,9,458,0.00010599,0.188231232,0.093777072,0.428511732,0.000838339,DB0036710037844_,7.084088199,-1.670084116,male,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,levonorgestrel,DB00367
,96872,DB00813,10025482,242,10330,90,10078,3.43583404550074e-16,2.623335579,2.04773783,3.38505171,2.41796246013352e-14,DB0081310025482_,31.35326608,0.96444663,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,96889,DB01033,10000081,43,1139,53,1251,0.603629605,0.891143384,0.576888007,1.369892456,0.747265626,DB0103310000081_,0.291334567,-0.11524994,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,mercaptopurine,DB01033
,96898,DB00541,10007515,50,3084,37,4260,0.004349766,1.866451362,1.192692523,2.944573535,0.018278752,DB0054110007515_,4.002015993,0.62403896,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,vincristine,DB00541
,96899,DB00563,10007515,60,46586,49,15299,5.73144515272262e-06,0.402132734,0.270994927,0.599302048,6.66155365197056e-05,DB0056310007515_,9.616572727,-0.910973062,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,methotrexate,DB00563
,96908,DB00563,10013442,44,46602,16,15332,0.764716573,0.904736571,0.500386553,1.718272498,0.8701171,DB0056310013442_,0.139127479,-0.10011146,NA,10013442,Disseminated intravascular coagulation,10005329,Blood and lymphatic system disorders,Blood,methotrexate,DB00563
,96911,DB00563,10013971,43,46603,25,15323,0.033669959,0.565541764,0.337587452,0.966552282,0.092710545,DB0056310013971_,2.37827306,-0.569971133,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,96913,DB01234,10013971,85,31540,87,32801,0.939223691,1.016075263,0.744285483,1.386734478,0.978804305,DB0123410013971_,0.021423549,0.015947424,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,96914,DB00541,10019211,83,3051,99,4198,0.362100443,1.153542249,0.847827131,1.566272077,0.531767688,DB0054110019211_,0.631548561,0.142837425,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,vincristine,DB00541
,96915,DB01033,10019211,46,1136,53,1251,0.838078409,0.955792453,0.624209362,1.458924473,0.916743627,DB0103310019211_,0.086927423,-0.045214489,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,mercaptopurine,DB01033
,96924,DB01033,10029354,47,1135,68,1236,0.152094562,0.75276917,0.503078309,1.118392621,0.28686295,DB0103310029354_,1.248750704,-0.283996645,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,mercaptopurine,DB01033
,96928,DB01033,10033661,45,1137,67,1237,0.121478249,0.730806563,0.485035538,1.092319034,0.243549505,DB0103310033661_,1.412435051,-0.313606474,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,mercaptopurine,DB01033
,96937,DB00541,10048294,42,3092,40,4257,0.11493658,1.445519778,0.912482607,2.293192849,0.233525439,DB0054110048294_,1.454464263,0.368468965,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,vincristine,DB00541
,96957,DB00295,10012218,73,14590,84,9518,0.000410907,0.566968239,0.408099675,0.786077445,0.002620667,DB0029510012218_,5.944326353,-0.567451992,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,morphine,DB00295
,96958,DB00695,10012218,67,27982,52,20476,0.780759268,0.942856025,0.646259968,1.382250394,0.880670187,DB0069510012218_,0.127072085,-0.058841686,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,96969,DB00425,10061284,49,12646,18,7466,0.099018473,1.607121276,0.918859895,2.93362934,0.209380198,DB0042510061284_,1.56360355,0.474444551,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,96982,DB00264,10035742,41,29566,65,24827,0.001659802,0.529678844,0.349147056,0.795325515,0.008345045,DB0026410035742_,4.786087335,-0.635484411,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,96983,DB00497,10035742,41,19226,48,16327,0.136840612,0.725383024,0.465950923,1.124614862,0.265284175,DB0049710035742_,1.326953669,-0.321055454,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,96985,DB00695,10035742,60,27989,59,20469,0.114317411,0.743731924,0.510189101,1.084452282,0.232608232,DB0069510035742_,1.458399647,-0.296074626,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,96987,DB00959,10035742,42,8036,48,4954,0.004388859,0.53946353,0.347300894,0.835026704,0.018410654,DB0095910035742_,3.994825784,-0.617180096,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,96990,DB01076,10035742,37,25710,63,25520,0.009079416,0.582971106,0.37743389,0.888932663,0.032963046,DB0107610035742_,3.412368153,-0.539617656,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,96994,DB00398,10003549,43,684,134,1404,0.023298989,0.658793704,0.450390958,0.947826109,0.069588539,DB0039810003549_,2.6651554,-0.417344838,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sorafenib,DB00398
,96995,DB00398,10010774,27,700,55,1483,0.904214088,1.03999404,0.62500948,1.693803434,0.957497529,DB0039810010774_,0.043432138,0.039214982,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sorafenib,DB00398
,96996,DB08895,10038435,53,28061,23,6623,0.018676392,0.543891763,0.327349673,0.930496568,0.0585426,DB0889510038435_,2.838000586,-0.609005017,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,tofacitinib,DB08895
,97000,DB00341,10042682,72,11333,16,5052,0.010409274,2.005927333,1.153964968,3.698953647,0.036738203,DB0034110042682_,3.303938123,0.696106464,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,97004,DB00230,10005191,86,19588,25,8626,0.078586174,1.514874356,0.960050482,2.470783066,0.175960437,DB0023010005191_,1.737496101,0.415332502,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,97006,DB01307,10011906,80,2444,125,1944,3.63947461758211e-06,0.509150374,0.377187417,0.684047762,4.47653674886035e-05,DB0130710011906_,10.01407576,-0.675011875,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,insulin detemir,DB01307
,97011,DB00112,10047571,84,5849,51,4040,0.482323202,1.137675217,0.791968816,1.648201489,0.64676387,DB0011210047571_,0.435774013,0.128986897,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,bevacizumab,DB00112
,97012,DB06655,10011906,30,3658,28,2091,0.073999611,0.612538544,0.352542776,1.067211608,0.168201295,DB0665510011906_,1.78259383,-0.49014341,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,liraglutide,DB06655
,97017,DB06655,10033609,34,3654,49,2070,2.82833974076502e-05,0.393148412,0.2452672,0.623705978,0.000269505,DB0665510033609_,8.218924209,-0.933568101,NA,10033609,Pancreatic carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,liraglutide,DB06655
,97024,DB00530,10013573,47,1761,21,1247,0.082458857,1.584612491,0.923359914,2.805660262,0.182474412,DB0053010013573_,1.701145323,0.460339892,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,erlotinib,DB00530
,97027,DB00530,10019211,43,1765,24,1244,0.382787679,1.262700842,0.744819502,2.187494173,0.55287931,DB0053010019211_,0.592615546,0.233252952,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,erlotinib,DB00530
,97033,DB00338,10033557,272,33402,73,22199,1.66600381212802e-13,2.476270672,1.904789494,3.253854603,8.30159435104928e-12,DB0033810033557_,25.51457353,0.906753667,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,omeprazole,DB00338
,97036,DB01409,10033557,63,5968,17,3949,0.000530346,2.451960573,1.414582305,4.476782064,0.003238553,DB0140910033557_,5.732628713,0.896887938,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,tiotropium,DB01409
,97053,DB00121,10035664,146,4077,18,450,0.689908475,0.895310638,0.540585726,1.568068497,0.812974205,DB0012110035664_,0.207055898,-0.11058454,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,biotin,DB00121
,97054,DB00668,10035664,293,9798,135,4168,0.453242475,0.923267995,0.747910118,1.144405209,0.620800837,DB0066810035664_,0.476744962,-0.079835735,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,epinephrine,DB00668
,97055,DB01296,10035664,51,1398,34,949,1,1.018233756,0.641469591,1.634203424,1,DB0129610035664_,0,0.018069514,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,glucosamine,DB01296
,97065,DB00646,10020937,50,3403,13,1987,0.008087348,2.24546258,1.198050635,4.517577354,0.03005244,DB0064610020937_,3.504811433,0.808911549,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,nystatin,DB00646
,97066,DB00678,10020937,178,15421,95,10629,0.047475274,1.291433171,0.999862276,1.676744034,0.120353722,DB0067810020937_,2.11732019,0.255752587,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,losartan,DB00678
,97068,DB01109,10020937,38,4374,19,4251,0.016805747,1.94360523,1.091021786,3.575399579,0.053906774,DB0110910020937_,2.920499123,0.664544614,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,heparin,DB01109
,97071,DB00196,10028372,41,5042,30,3255,0.626450833,0.882304695,0.536429227,1.46655476,0.766032897,DB0019610028372_,0.266530164,-0.125217824,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,fluconazole,DB00196
,97072,DB00678,10028372,122,15477,100,10624,0.193059605,0.837464582,0.636834434,1.103451269,0.340472456,DB0067810028372_,1.077421051,-0.177376307,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,97073,DB00736,10028372,78,10513,37,5516,0.693704366,1.106078469,0.737698427,1.685367748,0.815602588,DB0073610028372_,0.203828067,0.100820849,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,97074,DB01109,10028372,30,4382,30,4240,1,0.967590095,0.562457853,1.664496758,1,DB0110910028372_,0,-0.032946737,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,heparin,DB01109
,97076,DB01611,10028372,86,11827,22,2339,0.297330833,0.773108069,0.478351638,1.300089871,0.463227392,DB0161110028372_,0.769537218,-0.257336435,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,97092,DB00404,10046735,150,19742,32,9830,3.6893123016161e-06,2.333957836,1.583513799,3.537126283,4.52724434397662e-05,DB0040410046735_,10.00281202,0.847565469,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,97093,DB00557,10046735,126,5861,30,3037,5.48421030070241e-05,2.176155619,1.447858013,3.366649396,0.000477959,DB0055710046735_,7.645985372,0.777559843,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxyzine,DB00557
,97095,DB00476,10000125,38,17219,13,6164,1,1.046362135,0.544800753,2.142264774,1,DB0047610000125_,0,0.045319515,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,97133,DB00451,10023424,89,47182,14,15405,0.008156416,2.075475435,1.174046358,3.951101155,0.030266307,DB0045110023424_,3.497720153,0.730190253,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,97139,DB00451,10061011,43,47228,7,15412,0.099294159,2.004481157,0.893816773,5.282107333,0.209785946,DB0045110061011_,1.561667572,0.695385253,NA,10061011,Bladder disorder,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,97146,DB01137,10019063,38,7734,13,5580,0.021961524,2.108846202,1.097592768,4.318622918,0.066550457,DB0113710019063_,2.709794869,0.746140974,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,levofloxacin,DB01137
,97148,DB00190,10040047,16,3281,46,4628,0.01346633,0.490667602,0.258811401,0.884820477,0.045108002,DB0019010040047_,3.098695625,-0.711988361,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,carbidopa,DB00190
,97149,DB00215,10040047,79,11024,55,5221,0.032486623,0.680270344,0.475312996,0.979615833,0.090170104,DB0021510040047_,2.406057346,-0.385264996,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,citalopram,DB00215
,97161,DB09068,10067482,65,2330,27,959,1,0.990862549,0.619193608,1.625355733,1,DB0906810067482_,0,-0.009179454,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,vortioxetine,DB09068
,97162,DB00193,10022052,70,19250,17,8685,0.019993672,1.857717865,1.080968289,3.369479227,0.061747581,DB0019310022052_,2.784700485,0.61934878,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,97163,DB00788,10022052,64,9292,19,5042,0.020646403,1.827693854,1.079681299,3.23455602,0.063361436,DB0078810022052_,2.758899868,0.603054983,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,97165,DB00264,10022061,143,29464,43,24849,1.95218711064756e-10,2.804537898,1.981032715,4.043267006,6.07976755964113e-09,DB0026410022061_,18.91829937,1.031238783,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,97166,DB00788,10022061,124,9232,13,5048,6.52197415420165e-12,5.215955077,2.936463889,10.08013482,2.57983582608262e-10,DB0078810022061_,22.07812517,1.651722212,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,97168,DB00264,10022095,92,29515,38,24854,0.000138269,2.038656732,1.38226068,3.060042195,0.001051619,DB0026410022095_,6.857424202,0.712291126,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,97169,DB00736,10022095,43,10548,9,5544,0.008224868,2.511065838,1.206261505,5.862947402,0.030460115,DB0073610022095_,3.491337157,0.9207073,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,97176,DB00193,10053425,78,19242,16,8686,0.002462734,2.200563485,1.272894116,4.041107171,0.011530633,DB0019310053425_,4.462748082,0.788713457,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,97177,DB00264,10053425,95,29512,26,24866,3.94525631563305e-08,3.078445842,1.976812408,4.952671571,7.77952455036869e-07,DB0026410053425_,14.06660043,1.124424873,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,97178,DB00736,10053425,47,10544,7,5546,0.000493276,3.531409103,1.584802726,9.265846818,0.003058684,DB0073610053425_,5.789770572,1.261696971,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,97209,DB00016,10007559,39,2723,37,2253,0.563636797,0.872145455,0.539737811,1.411493503,0.715554261,DB0001610007559_,0.334697846,-0.136799062,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,erythropoietin,DB00016
,97215,DB00695,10033664,48,28001,9,20519,3.67336652774532e-05,3.90811615,1.896092811,9.061638827,0.000339025,DB0069510033664_,7.989435473,1.363055455,female,10033664,Panic attack,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,97223,DB00285,10019303,55,10896,14,3704,0.405403099,1.33544085,0.731573904,2.603763317,0.575055776,DB0028510019303_,0.553288241,0.289261462,NA,10019303,Heart rate increased,10022891,Investigations,Inv,venlafaxine,DB00285
,97234,DB01611,10051118,37,11876,22,2339,0.000122787,0.331272236,0.189949437,0.590696943,0.000950776,DB0161110051118_,6.958231568,-1.104814776,male,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,97237,DB08908,10047513,70,10603,25,3254,0.543617875,0.859341057,0.536311467,1.41882938,0.698779658,DB0890810047513_,0.358419811,-0.151589397,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,dimethyl fumarate,DB08908
,97239,DB00745,10002855,122,2455,48,1035,0.731291447,1.071516709,0.754808736,1.541731595,0.843717576,DB0074510002855_,0.169937466,0.069075129,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,modafinil,DB00745
,97240,DB00115,10016825,144,18281,46,10426,0.000466248,1.785312118,1.271667191,2.547851876,0.002913877,DB0011510016825_,5.838270716,0.579593256,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,cyanocobalamin,DB00115
,97242,DB08908,10022000,79,10594,37,3242,0.036561668,0.653421374,0.435949727,0.995488831,0.098687969,DB0890810022000_,2.315792239,-0.425533068,NA,10022000,Influenza,10021881,Infections and infestations,Infec,dimethyl fumarate,DB08908
,97244,DB00115,10057668,71,18354,49,10423,0.296488547,0.822872751,0.563325142,1.210575061,0.462367337,DB0011510057668_,0.771395602,-0.194953706,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,97252,DB00635,10011781,115,32938,35,23759,2.66699104481221e-06,2.370011634,1.610232341,3.567750717,3.41211290401017e-05,DB0063510011781_,10.28559375,0.862894864,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,prednisone,DB00635
,97258,DB00316,10013722,70,65404,30,36923,0.213300176,1.317253497,0.847274876,2.093576857,0.365405229,DB0031610013722_,1.006748324,0.275548885,NA,10013722,Drug level increased,10022891,Investigations,Inv,acetaminophen,DB00316
,97259,DB00230,10022523,30,19644,36,8615,7.15713204413458e-05,0.365477696,0.217289607,0.61075672,0.000597982,DB0023010022523_,7.421949487,-1.006550025,male,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,97262,DB01050,10023676,38,18070,21,9350,0.785223617,0.936309118,0.535366275,1.680345861,0.88348663,DB0105010023676_,0.12387912,-0.065809603,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,ibuprofen,DB01050
,97266,DB00316,10038661,30,65444,20,36933,0.558899503,0.846526537,0.464996339,1.572992334,0.711740192,DB0031610038661_,0.340042333,-0.166613728,NA,10038661,Respiratory acidosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,97279,DB00047,10008469,40,9245,38,8480,0.909868959,0.965520347,0.60303107,1.548198084,0.959437782,DB0004710008469_,0.04140781,-0.035088103,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,97292,DB01104,10022052,47,15416,12,7274,0.068166895,1.848024866,0.96450676,3.82964203,0.157997163,DB0110410022052_,1.845178203,0.614117429,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,97297,DB00646,10037153,43,3410,7,1993,0.000562893,3.589577926,1.59693808,9.474007107,0.003404429,DB0064610037153_,5.682678188,1.278034626,female,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,nystatin,DB00646
,97304,DB00051,10040831,88,25643,39,11381,1,1.001450911,0.679028986,1.501039613,1,DB0005110040831_,0,0.001449859,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,97305,DB00051,10042682,95,25636,25,11395,0.01737086,1.689048628,1.077056251,2.741099726,0.055344613,DB0005110042682_,2.894175953,0.524165429,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,97307,DB00285,10042128,50,10901,6,3712,0.008754591,2.8376529,1.214662002,8.105278926,0.032015921,DB0028510042128_,3.441521973,1.042977267,female,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,97317,DB00706,10011781,6,1069,45,15880,0.136740025,1.980575776,0.688925674,4.670545112,0.26515137,DB0070610011781_,1.32745441,0.683387598,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,tamsulosin,DB00706
,97322,DB01020,10013968,117,1696,119,1759,0.893139172,1.019713281,0.776189986,1.339450341,0.955474763,DB0102010013968_,0.045546928,0.019521491,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,isosorbide mononitrate,DB01020
,97323,DB00285,10008190,76,10875,26,3692,1,0.992368224,0.627215034,1.617001288,1,DB0028510008190_,0,-0.007661047,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,97324,DB00656,10008190,76,11937,53,6566,0.196473529,0.788784065,0.547393266,1.143775885,0.34471889,DB0065610008190_,1.065026007,-0.237262677,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,97326,DB01062,10008190,38,4448,21,1724,0.192147026,0.701396109,0.400011619,1.26185889,0.33936399,DB0106210008190_,1.08068203,-0.354682489,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,97329,DB08910,10061822,229,16515,202,17286,0.080925031,1.18658055,0.976515326,1.442750566,0.179936087,DB0891010061822_,1.715153564,0.171075684,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,97330,DB01238,10041349,132,5118,113,3389,0.054902123,0.773545156,0.594780592,1.007369507,0.134156885,DB0123810041349_,2.008745382,-0.256771232,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,97341,DB01016,10016173,33,1068,31,1197,0.526641567,1.193002075,0.702999111,2.029299729,0.684387986,DB0101610016173_,0.379230291,0.176472883,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,glyburide,DB01016
,97342,DB00706,10061818,14,1061,193,15732,0.773101496,1.075532329,0.575068359,1.857272622,0.875922879,DB0070610061818_,0.132477229,0.072815729,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,97358,DB01202,10029354,40,6674,72,5646,0.000119755,0.470007575,0.310518546,0.702461947,0.000929912,DB0120210029354_,6.980420594,-0.755006467,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,levetiracetam,DB01202
,97359,DB01225,10029354,62,4982,63,4577,0.58978173,0.904134546,0.624794977,1.307999513,0.736561637,DB0122510029354_,0.305762358,-0.100777096,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,enoxaparin,DB01225
,97370,DB00381,10005169,53,29307,28,22859,0.11610947,1.476385845,0.916819794,2.425024485,0.235307434,DB0038110005169_,1.446862389,0.389597105,NA,10005169,Blindness,10015919,Eye disorders,Eye,amlodipine,DB00381
,97384,DB00678,10007739,77,15522,37,10687,0.085093052,1.432818199,0.955302325,2.183651646,0.186918843,DB0067810007739_,1.67708075,0.359643273,NA,10007739,Cataract,10015919,Eye disorders,Eye,losartan,DB00678
,97396,DB00207,10022000,127,8953,93,5362,0.160399712,0.817880846,0.619578797,1.082968465,0.29803177,DB0020710022000_,1.210555189,-0.201038618,NA,10022000,Influenza,10021881,Infections and infestations,Infec,azithromycin,DB00207
,97397,DB00381,10022000,304,29056,186,22701,0.009080691,1.276931003,1.059584987,1.542213316,0.032965399,DB0038110022000_,3.41229677,0.244459545,NA,10022000,Influenza,10021881,Infections and infestations,Infec,amlodipine,DB00381
,97398,DB00471,10022000,217,13972,73,5392,0.355210221,1.147159071,0.874337992,1.519768243,0.524976141,DB0047110022000_,0.644402463,0.137288513,NA,10022000,Influenza,10021881,Infections and infestations,Infec,montelukast,DB00471
,97399,DB00678,10022000,191,15408,70,10654,3.28554917315388e-06,1.886645276,1.425875019,2.520818433,4.09874988212386e-05,DB0067810022000_,10.10224344,0.634800266,NA,10022000,Influenza,10021881,Infections and infestations,Infec,losartan,DB00678
,97400,DB00758,10022000,83,8217,71,10003,0.03420574,1.423062138,1.02264949,1.984772575,0.093812382,DB0075810022000_,2.366458423,0.352810985,NA,10022000,Influenza,10021881,Infections and infestations,Infec,clopidogrel,DB00758
,97402,DB00950,10022000,55,4663,23,2033,1,1.042551618,0.628173908,1.782811436,1,DB0095010022000_,0,0.041671187,NA,10022000,Influenza,10021881,Infections and infestations,Infec,fexofenadine,DB00950
,97403,DB14512,10022000,45,4799,20,2392,0.791543572,1.121460402,0.647085453,2.009790205,0.887203509,DB1451210022000_,0.119680888,0.114631766,NA,10022000,Influenza,10021881,Infections and infestations,Infec,mometasone furoate,DB14512
,97404,DB00950,10025482,149,4569,38,2018,0.002115387,1.731694457,1.200541651,2.552482398,0.010186487,DB0095010025482_,4.586693222,0.549100384,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,97416,DB00588,10040742,39,16485,17,8451,0.672147463,1.176050301,0.649455545,2.218519119,0.800970013,DB0058810040742_,0.22193177,0.162161622,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,97421,DB00207,10040753,252,8828,73,5382,5.18727874715453e-09,2.104447064,1.611938121,2.775973027,1.24065170035448e-07,DB0020710040753_,15.90245884,0.744052755,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,azithromycin,DB00207
,97422,DB00678,10040753,221,15378,70,10654,2.07995448569809e-09,2.187219758,1.662466385,2.907940273,5.41571111011138e-08,DB0067810040753_,16.73137655,0.782631221,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,losartan,DB00678
,97423,DB00758,10040753,85,8215,26,10048,1.79076950384263e-11,3.998409172,2.548186882,6.471460243,6.55576273098934e-10,DB0075810040753_,21.14550646,1.385896575,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,clopidogrel,DB00758
,97424,DB00950,10040753,185,4533,43,2013,9.38068707153202e-05,1.910403229,1.358267835,2.739715212,0.000755427,DB0095010040753_,7.188227459,0.647314335,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,fexofenadine,DB00950
,97454,DB00788,10048294,40,9316,33,5028,0.08451262,0.654196258,0.401699035,1.072058268,0.185892402,DB0078810048294_,1.682587254,-0.424347883,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,naproxen,DB00788
,97457,DB00956,10021789,38,5776,20,3447,0.685449777,1.133889686,0.642221588,2.060399528,0.810082612,DB0095610021789_,0.210619046,0.125653922,NA,10021789,Infection,10021881,Infections and infestations,Infec,hydrocodone,DB00956
,97463,DB00688,10013950,45,6445,34,5344,0.734367865,1.097458115,0.686381362,1.769439869,0.846282579,DB0068810013950_,0.166901957,0.092996701,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,mycophenolate mofetil,DB00688
,97467,DB01050,10062237,37,18071,20,9351,0.889203429,0.957309856,0.541071641,1.741753808,0.953968782,DB0105010062237_,0.047124331,-0.043628162,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,ibuprofen,DB01050
,97470,DB00264,10016750,37,29570,21,24871,0.186795017,1.48190476,0.844798429,2.665192246,0.332469326,DB0026410016750_,1.101207675,0.39332826,NA,10016750,Flank pain,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,97476,DB00264,10037400,153,29454,82,24810,0.000993113,1.571648453,1.19349925,2.082338209,0.005469667,DB0026410037400_,5.208537558,0.452125039,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,97481,DB01229,10033609,22,5719,55,2654,1.42335898685832e-12,0.185675464,0.107574508,0.310257588,6.2481175337256e-11,DB0122910033609_,23.4961558,-1.683754946,male,10033609,Pancreatic carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,paclitaxel,DB01229
,97482,DB09053,10013968,72,2213,145,3907,0.388637633,0.876649531,0.648222004,1.176887332,0.558595389,DB0905310013968_,0.58232988,-0.131647989,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibrutinib,DB09053
,97483,DB00451,10035598,244,47027,124,15295,9.54721375790929e-05,0.63999119,0.513078576,0.801613749,0.000765904,DB0045110035598_,7.174453451,-0.446300868,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,97488,DB00332,10037660,80,2604,55,1601,0.529936329,0.894314068,0.622761719,1.292189326,0.687116507,DB0033210037660_,0.375251414,-0.111698259,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ipratropium,DB00332
,97499,DB09153,10038687,36,7763,34,5665,0.331781711,0.772692143,0.469322534,1.274553551,0.500610332,DB0915310038687_,0.691927261,-0.257874573,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,97500,DB00005,10053762,3854,124228,1683,40736,3.44567500632106e-21,0.75090905,0.708125083,0.796503352,4.08891952781711e-19,DB0000510053762_,42.34083601,-0.286470739,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,97501,DB00737,10053762,82,2719,18,914,0.127050984,1.531147883,0.905208088,2.726143484,0.251497669,DB0073710053762_,1.380321557,0.426017705,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,meclizine,DB00737
,97511,DB01098,10042674,64,8085,23,7186,0.000133254,2.472953607,1.512576182,4.178773988,0.001018043,DB0109810042674_,6.889873139,0.905413229,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,97513,DB00656,10002034,109,11904,51,6568,0.361927679,1.179191007,0.836923934,1.680740331,0.531668232,DB0065610002034_,0.631735608,0.164828616,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,trazodone,DB00656
,97522,DB00327,10021097,116,6022,103,4159,0.070946579,0.777829665,0.589534988,1.027431841,0.162966953,DB0032710021097_,1.814207844,-0.251247718,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,hydromorphone,DB00327
,97545,DB01164,10003988,38,6486,30,7906,0.086818313,1.543915465,0.930351895,2.583572087,0.189765029,DB0116410003988_,1.661968662,0.434321699,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium chloride,DB01164
,97550,DB01156,10013654,122,13500,223,6105,1.26669208472769e-36,0.247449906,0.196361639,0.310588177,4.29612921897643e-34,DB0115610013654_,76.83017873,-1.396547117,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,97552,DB00654,10003239,64,3752,23,2575,0.007967173,1.90952117,1.165748627,3.231695355,0.029694029,DB0065410003239_,3.516809303,0.646852514,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,latanoprost,DB00654
,97553,DB01296,10003239,67,1382,19,964,0.000313565,2.458913669,1.448095076,4.364664685,0.002092955,DB0129610003239_,6.169178534,0.899719655,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,glucosamine,DB01296
,97559,DB06724,10023232,88,7841,23,3896,0.004502848,1.900997103,1.18796833,3.158336396,0.018788374,DB0672410023232_,3.974516983,0.64237854,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,97563,DB00654,10033425,56,3760,29,2569,0.266077727,1.319313003,0.825619766,2.149209283,0.428203824,DB0065410033425_,0.848155972,0.277111149,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,latanoprost,DB00654
,97564,DB01296,10033425,58,1391,18,965,0.002754008,2.234719573,1.288317153,4.057315502,0.012602561,DB0129610033425_,4.373855271,0.804115749,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,glucosamine,DB01296
,97567,DB00654,10048959,57,3759,20,2578,0.009799125,1.954393432,1.153083207,3.442976246,0.035010195,DB0065410048959_,3.352115984,0.67007988,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,97568,DB01156,10048959,141,13481,56,6272,0.355946558,1.171405684,0.852396456,1.628820371,0.525628851,DB0115610048959_,0.643159922,0.158204467,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,97571,DB08932,10048959,1060,18383,323,6274,0.086199869,1.120027638,0.984534363,1.276790239,0.188687838,DB0893210048959_,1.667661281,0.113353361,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,97575,DB01080,10037660,40,2019,42,2070,1,0.976439737,0.614285073,1.549930485,1,DB0108010037660_,0,-0.023842244,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,vigabatrin,DB01080
,97581,DB00331,10036790,86,24860,49,20703,0.037452439,1.461605202,1.016948022,2.121438902,0.10048868,DB0033110036790_,2.297710196,0.379535285,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,97584,DB00175,10069327,42,8089,22,6084,0.205324904,1.435852316,0.836878016,2.528605731,0.355566433,DB0017510069327_,1.034043176,0.361758621,NA,10069327,Product quality issue,10077536,Product issues,Prod,pravastatin,DB00175
,97593,DB00959,10043071,103,7975,70,4932,0.581583376,0.909987483,0.663756343,1.253775506,0.729894913,DB0095910043071_,0.31485471,-0.094324435,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,methylprednisolone,DB00959
,97604,DB01225,10069803,52,4992,10,4630,2.52826310906794e-07,4.822141533,2.420769624,10.65201331,4.18907117950701e-06,DB0122510069803_,12.38303152,1.573218131,female,10069803,Injury associated with device,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,97608,DB00864,10000059,67,6802,36,8356,5.71528193992334e-05,2.286196351,1.50075719,3.534197765,0.000494816,DB0086410000059_,7.611324261,0.826889455,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,97611,DB00864,10028334,49,6820,45,8347,0.176914543,1.33265597,0.869661119,2.046448842,0.319953127,DB0086410028334_,1.139580771,0.287173921,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,tacrolimus,DB00864
,97618,DB00996,10016338,46,38907,21,22404,0.446635824,1.261376132,0.737413595,2.225920607,0.614378321,DB0099610016338_,0.487144382,0.232203294,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,97655,DB01229,10016825,141,5600,46,2663,0.026574427,1.45755976,1.03446345,2.086856011,0.077025839,DB0122910016825_,2.563614337,0.37676364,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,paclitaxel,DB01229
,97656,DB01229,10051792,120,5621,41,2668,0.073550629,1.389181292,0.963823881,2.038139113,0.167441388,DB0122910051792_,1.787121909,0.328714575,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,paclitaxel,DB01229
,97659,DB01075,10040753,998,18950,283,10814,4.87633107400151e-27,2.012387348,1.758002201,2.309317456,8.68978727322914e-25,DB0107510040753_,55.40247887,0.699321752,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,97660,DB06285,10040753,51,8799,8,1098,0.531323016,0.795537078,0.373449846,1.946337963,0.688158145,DB0628510040753_,0.373736606,-0.228737822,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,teriparatide,DB06285
,97671,DB00005,10072227,60,128022,28,42391,0.139035772,0.709550583,0.445910999,1.154528058,0.268480405,DB0000510072227_,1.314977346,-0.34312349,NA,10072227,Neck surgery,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,97676,DB00515,10033661,48,1822,75,2076,0.098580192,0.729278762,0.493949648,1.067964282,0.208748569,DB0051510033661_,1.56662477,-0.315699231,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,cisplatin,DB00515
,97678,DB08908,10015150,127,10546,25,3254,0.042901691,1.567365104,1.012698329,2.517514741,0.111500491,DB0890810015150_,2.19372628,0.449395932,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,dimethyl fumarate,DB08908
,97682,DB00051,10005191,111,25620,36,11384,0.107106267,1.370089988,0.932447596,2.056216985,0.221772282,DB0005110005191_,1.506104179,0.314876422,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,97688,DB00213,10042458,66,18829,27,13394,0.015101285,1.738820834,1.095061584,2.832507384,0.049589265,DB0021310042458_,3.003980906,0.553207202,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,97689,DB00230,10042458,218,19456,131,8520,0.004967501,0.728733613,0.583194347,0.913561497,0.020353978,DB0023010042458_,3.894478927,-0.316447029,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,97705,DB00264,10016766,112,29495,83,24809,0.388641892,1.134996432,0.84644434,1.527121259,0.558595389,DB0026410016766_,0.58232988,0.126629507,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,97711,DB00722,10041101,33,25370,33,25999,1,1.024797384,0.612851036,1.713673418,1,DB0072210041101_,0,0.024494919,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,97712,DB00863,10041101,31,10642,20,5820,0.560380122,0.847695768,0.467512891,1.570792551,0.713038436,DB0086310041101_,0.338219952,-0.165233472,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,97716,DB00158,10019303,69,16746,18,8086,0.021211927,1.850928586,1.088423618,3.307209006,0.064794364,DB0015810019303_,2.736536656,0.615687451,NA,10019303,Heart rate increased,10022891,Investigations,Inv,folic acid,DB00158
,97718,DB00787,10019303,62,16938,46,17202,0.122741749,1.368815553,0.919200299,2.051460641,0.245326313,DB0078710019303_,1.405166065,0.313945806,NA,10019303,Heart rate increased,10022891,Investigations,Inv,acyclovir,DB00787
,97721,DB01104,10011469,84,15379,16,7270,0.000352722,2.481708873,1.441448567,4.542753127,0.002307492,DB0110410011469_,6.07159418,0.908947384,NA,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,97730,DB00904,10005191,87,22982,31,14425,0.005880503,1.761484669,1.156220625,2.748498092,0.023299522,DB0090410005191_,3.75932242,0.566157015,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,97739,DB00904,10014387,167,22902,184,14272,1.37634718305905e-07,0.565631402,0.45541771,0.702025214,2.43208643406434e-06,DB0090410014387_,12.92676105,-0.569812647,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,ondansetron,DB00904
,97760,DB01174,10013700,67,872,13,779,2.57665297214501e-08,4.600609449,2.492476855,9.158792438,5.27882489266029e-07,DB0117410013700_,14.45439214,1.526188784,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,phenobarbital,DB01174
,97762,DB00661,10000081,43,3485,14,1581,0.316361582,1.393331222,0.745068593,2.766042603,0.484039942,DB0066110000081_,0.72558785,0.331697443,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,verapamil,DB00661
,97767,DB00273,10038695,50,8431,11,2182,0.751016017,1.176376082,0.603235192,2.510140567,0.85930813,DB0027310038695_,0.151627714,0.162438596,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,topiramate,DB00273
,97769,DB01080,10038695,44,2015,25,2087,0.020432792,1.822617985,1.086602887,3.119837399,0.062848976,DB0108010038695_,2.767020633,0.600273921,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vigabatrin,DB01080
,97775,DB00028,10008479,163,13295,69,5546,0.942240774,0.985440158,0.737875922,1.327940479,0.981388019,DB0002810008479_,0.018787363,-0.014666876,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,97777,DB09037,10035742,63,2463,73,2762,0.862348365,0.967780736,0.676579303,1.381044593,0.936065529,DB0903710035742_,0.066069796,-0.03274973,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pembrolizumab,DB09037
,97780,DB00207,10037087,158,8922,58,5397,0.001080425,1.647802084,1.2098224,2.271089797,0.005872408,DB0020710037087_,5.137490525,0.499442329,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,azithromycin,DB00207
,97781,DB00254,10037087,139,5796,54,3334,0.015363968,1.480610793,1.070555493,2.073149205,0.050238999,DB0025410037087_,2.990963691,0.392454701,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,doxycycline,DB00254
,97792,DB00999,10021519,38,21392,20,12219,0.891458282,1.085276724,0.615510068,1.969507366,0.954926275,DB0099910021519_,0.046121141,0.081835,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,97798,DB00334,10037844,33,2816,19,2793,0.069420427,1.722484078,0.948572984,3.214538703,0.160269699,DB0033410037844_,1.830897261,0.54376748,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,olanzapine,DB00334
,97799,DB00425,10044034,30,12665,22,7462,0.473076489,0.80345144,0.447799955,1.462917141,0.639075704,DB0042510044034_,0.447732359,-0.218838532,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,97805,DB01234,10021654,49,31576,46,32842,0.681485267,1.107923733,0.72539141,1.694761404,0.807434868,DB0123410021654_,0.213892886,0.102487752,NA,10021654,Increased appetite,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,97808,DB00188,10022437,115,7771,87,8741,0.005619017,1.486786837,1.113627693,1.990989508,0.022464958,DB0018810022437_,3.795798597,0.396617306,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,bortezomib,DB00188
,97809,DB00007,10002855,38,1909,35,4417,0.000157448,2.511704847,1.539456,4.108346442,0.001176053,DB0000710002855_,6.745591644,0.920961744,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,leuprolide,DB00007
,97810,DB00007,10018884,10,1937,44,4408,0.073291425,0.517246908,0.231611491,1.045892503,0.167003173,DB0000710018884_,1.789742466,-0.65923494,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,leuprolide,DB00007
,97811,DB00399,10018884,83,6909,55,4943,0.728484876,1.079679414,0.757124601,1.550042017,0.841717217,DB0039910018884_,0.172311168,0.076664158,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,zoledronic acid,DB00399
,97814,DB00399,10030095,44,6948,19,4979,0.072510014,1.659445345,0.947548676,3.013540104,0.165690916,DB0039910030095_,1.797631179,0.506483417,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,97816,DB01234,10030095,133,31492,115,32773,0.161406552,1.203560078,0.930170641,1.559204744,0.299341793,DB0123410030095_,1.206169238,0.185283896,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,97818,DB00399,10047942,214,6778,146,4852,0.704073954,1.049256049,0.843345838,1.308367373,0.822564291,DB0039910047942_,0.195328634,0.048081388,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,zoledronic acid,DB00399
,97823,DB00230,10029354,35,19639,29,8622,0.013860295,0.529843474,0.314430886,0.899273426,0.046186339,DB0023010029354_,3.075071218,-0.635173648,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,pregabalin,DB00230
,97825,DB00158,10047942,175,16640,106,7998,0.063422448,0.793555005,0.618944246,1.021372881,0.149659668,DB0015810047942_,1.899391443,-0.231232421,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,folic acid,DB00158
,97845,DB01060,10000059,106,8481,47,5034,0.109728405,1.33864438,0.939142115,1.933303937,0.22564631,DB0106010000059_,1.488786505,0.291657445,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,97847,DB08890,10010774,97,1850,23,536,0.433306866,1.221804619,0.760169745,2.038781946,0.601795976,DB0889010010774_,0.507836802,0.200328962,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,linaclotide,DB08890
,97848,DB09072,10010774,67,6404,12,2523,0.008239982,2.19952163,1.177369075,4.475686059,0.030498167,DB0907210010774_,3.490088699,0.788239896,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,sodium oxybate,DB09072
,97849,DB01060,10047895,126,8461,117,4964,0.000474047,0.631871949,0.486114315,0.821811837,0.002954431,DB0106010047895_,5.824449063,-0.459068518,NA,10047895,Weight decreased,10022891,Investigations,Inv,amoxicillin,DB01060
,97857,DB00316,10005746,54,65420,21,36932,0.151048099,1.451660898,0.862213554,2.530981032,0.285345643,DB0031610005746_,1.254054053,0.372708348,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,97858,DB00381,10005746,50,29310,38,22849,1,1.025743178,0.659100872,1.60806689,1,DB0038110005746_,0,0.025417402,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,97859,DB00722,10005746,33,25370,36,25996,0.81078914,0.939263277,0.567355531,1.550341576,0.89822005,DB0072210005746_,0.107340197,-0.062659459,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,lisinopril,DB00722
,97863,DB00745,10008479,45,2532,11,1072,0.106424015,1.731782265,0.877683693,3.727405501,0.220750886,DB0074510008479_,1.510720426,0.549151089,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,modafinil,DB00745
,97864,DB01050,10010264,316,17792,142,9229,0.164205622,1.154307,0.942414642,1.419537114,0.303025576,DB0105010010264_,1.193938069,0.143500164,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,97865,DB00381,10013496,52,29308,26,22861,0.067734072,1.560036304,0.956204413,2.60368683,0.157243548,DB0038110013496_,1.849959415,0.444709093,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,97867,DB01050,10013496,55,18053,19,9352,0.14102285,1.49954048,0.875520058,2.677192348,0.271310932,DB0105010013496_,1.304489765,0.405158715,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,97869,DB01050,10016825,94,18014,44,9327,0.652776876,1.106123615,0.764651598,1.621916823,0.786930847,DB0105010016825_,0.239614903,0.100861664,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,ibuprofen,DB01050
,97870,DB00381,10019304,55,29305,32,22855,0.195916324,1.340446083,0.851378595,2.142836104,0.344198158,DB0038110019304_,1.066537747,0.293002456,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,amlodipine,DB00381
,97873,DB01050,10030124,110,17998,53,9318,0.740385712,1.074517455,0.766672948,1.522333991,0.850848768,DB0105010030124_,0.161520877,0.071871682,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,97874,DB00316,10034960,81,65393,28,36925,0.027641245,1.633481044,1.05098987,2.608682366,0.079438082,DB0031610034960_,2.532777398,0.490713348,NA,10034960,Photophobia,10015919,Eye disorders,Eye,acetaminophen,DB00316
,97898,DB00745,10047899,53,2524,22,1061,1,1.012697264,0.601897587,1.757923332,1,DB0074510047899_,0,0.012617329,NA,10047899,Weight increased,10022891,Investigations,Inv,modafinil,DB00745
,97905,DB00515,10070863,26,1844,38,2113,0.377751861,0.784070145,0.4552072,1.331276756,0.547720732,DB0051510070863_,0.601989736,-0.243256792,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,cisplatin,DB00515
,97916,DB00927,10024264,36,7461,24,4992,1,1.003618562,0.581648401,1.760693283,1,DB0092710024264_,0,0.003612031,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,97945,DB00563,10061194,101,46545,26,15322,0.303445963,1.278749195,0.823876591,2.051851552,0.469955052,DB0056310061194_,0.755118222,0.245882409,NA,10061194,Hand deformity,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,97958,DB00413,10025482,67,2132,13,1194,0.000200829,2.885602722,1.570220969,5.723248172,0.001446028,DB0041310025482_,6.538934926,1.059733794,female,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,pramipexole,DB00413
,97965,DB00695,10062519,43,28006,25,20503,0.391462163,1.259193643,0.751629992,2.152062021,0.561325586,DB0069510062519_,0.577454175,0.23047155,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,97968,DB00230,10028411,263,19411,62,8589,3.64132878922106e-06,1.876939495,1.416618225,2.520135871,4.47776969472166e-05,DB0023010028411_,10.01380038,0.629642522,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,97980,DB00333,10061428,24,3047,37,3115,0.12383318,0.663170986,0.378550913,1.141590771,0.24684932,DB0033310061428_,1.398977169,-0.410722425,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,methadone,DB00333
,97988,DB00697,10020937,156,5940,21,1785,0.000262206,2.232007692,1.40522756,3.719364165,0.00180681,DB0069710020937_,6.316192633,0.802901491,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,97989,DB00697,10042458,60,6036,14,1792,0.487871775,1.272322528,0.700647387,2.47143974,0.651528496,DB0069710042458_,0.428434145,0.240843992,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,tizanidine,DB00697
,97992,DB13961,10074903,48,9409,25,6389,0.338975294,1.303717195,0.787136958,2.208931071,0.508057234,DB1396110074903_,0.677161171,0.265219565,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,fish oil,DB13961
,97993,DB08890,10053762,126,1821,47,512,0.129373647,0.753850232,0.526922285,1.093372177,0.254725566,DB0889010053762_,1.367568526,-0.282561562,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,linaclotide,DB08890
,97999,DB00158,10019063,48,16767,41,8063,0.008731941,0.562986449,0.363004563,0.876770197,0.031953092,DB0015810019063_,3.443486329,-0.57449972,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,folic acid,DB00158
,98000,DB00169,10019063,187,38504,172,18003,2.9772102763873e-10,0.508325744,0.410724398,0.629507114,9.02086133888647e-09,DB0016910019063_,18.52372602,-0.676632809,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,98008,DB00169,10028347,60,38631,22,18153,0.345261857,1.281520634,0.774372648,2.194837611,0.514705002,DB0016910028347_,0.664161354,0.248047368,NA,10028347,Muscle twitching,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,98012,DB00169,10040979,116,38575,68,18107,0.154109421,0.800762767,0.588232486,1.097302629,0.28968185,DB0016910040979_,1.238972029,-0.222190546,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,98014,DB00422,10040979,42,3393,26,2923,0.22130637,1.391547094,0.831200354,2.370366757,0.375144894,DB0042210040979_,0.980442943,0.330416145,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylphenidate,DB00422
,98022,DB00422,10047513,37,3398,16,2933,0.018916498,1.995798978,1.080602591,3.851268229,0.059150624,DB0042210047513_,2.82766814,0.69104446,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,methylphenidate,DB00422
,98023,DB01592,10047513,48,6228,14,3053,0.102739575,1.680620073,0.90966176,3.306276759,0.215137202,DB0159210047513_,1.536479306,0.519162816,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,iron,DB01592
,98027,DB00567,10038435,42,4477,33,2048,0.023994124,0.582253305,0.359121922,0.951174355,0.071227686,DB0056710038435_,2.641873687,-0.540849694,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,cephalexin,DB00567
,98034,DB00316,10061273,74,65400,41,36912,1,1.018680118,0.686260857,1.530915377,1,DB0031610061273_,0,0.018507788,NA,10061273,Malnutrition,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,98037,DB00567,10061428,67,4452,33,2048,0.745736939,0.933987083,0.604661226,1.468188847,0.854849343,DB0056710061428_,0.156830033,-0.068292671,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,cephalexin,DB00567
,98038,DB00956,10061428,93,5721,65,3402,0.320829632,0.850829804,0.611283529,1.190266813,0.489096791,DB0095610061428_,0.715194873,-0.161543166,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,hydrocodone,DB00956
,98047,DB01238,10039626,21,5229,30,3472,0.009157993,0.464828513,0.252517924,0.840917591,0.033181866,DB0123810039626_,3.405751742,-0.76608673,NA,10039626,Schizophrenia,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,98053,DB00404,10000060,142,19750,46,9816,0.0103276,1.534235915,1.092080826,2.190769474,0.03651368,DB0040410000060_,3.310068284,0.428032482,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,98055,DB08890,10000087,48,1899,7,552,0.10062657,1.992690676,0.889773793,5.25006264,0.211809361,DB0889010000087_,1.552068651,0.689485824,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,linaclotide,DB08890
,98064,DB00736,10005724,52,10539,21,5532,0.326625506,1.29978285,0.768521959,2.274244343,0.495061206,DB0073610005724_,0.703073876,0.262197212,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,esomeprazole,DB00736
,98065,DB00863,10005724,48,10625,17,5823,0.152050292,1.547388614,0.873023132,2.872926166,0.286806023,DB0086310005724_,1.24894917,0.436568745,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,ranitidine,DB00863
,98067,DB01118,10010264,47,3016,59,4650,0.317317865,1.228151048,0.816625727,1.838196734,0.485121857,DB0111810010264_,0.723355169,0.205509826,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,98068,DB13961,10010264,207,9250,80,6334,8.69750178892925e-06,1.77174299,1.359567066,2.327829672,9.6116810814381e-05,DB1396110010264_,9.249946327,0.571963802,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,98069,DB01118,10013709,114,2949,249,4460,0.001393588,0.692445644,0.547094303,0.872199553,0.007231359,DB0111810013709_,4.929328333,-0.367525537,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,98071,DB00863,10042772,105,10568,47,5793,0.268512451,1.224566322,0.858884645,1.769024907,0.430942554,DB0086310042772_,0.841780483,0.202586759,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,98072,DB01118,10042772,41,3022,64,4645,1,0.984681444,0.646759889,1.484466413,1,DB0111810042772_,0,-0.015437097,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,amiodarone,DB01118
,98073,DB13961,10042772,59,9398,68,6346,0.003501439,0.58591617,0.405648709,0.844108404,0.015331083,DB1396110042772_,4.177872947,-0.534578554,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,98076,DB00121,10000059,61,4162,8,460,0.683526009,0.842777241,0.398453299,2.052513057,0.808682962,DB0012110000059_,0.212348328,-0.171052602,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,biotin,DB00121
,98077,DB00213,10000059,265,18630,116,13305,8.14854388284715e-06,1.631483228,1.305179952,2.049660969,9.09295164341487e-05,DB0021310000059_,9.305425896,0.489489557,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,98080,DB00281,10000059,93,11365,36,5635,0.223022052,1.280901482,0.861851496,1.940619217,0.37724088,DB0028110000059_,0.974871358,0.247564113,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,98083,DB00668,10000059,53,10038,23,4280,1,0.982528113,0.590945383,1.68197673,1,DB0066810000059_,0,-0.017626322,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,epinephrine,DB00668
,98087,DB00916,10000059,62,5261,12,2419,0.003669664,2.375406873,1.264819989,4.852107706,0.015919643,DB0091610000059_,4.140201518,0.865168738,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,metronidazole,DB00916
,98088,DB01137,10000059,53,7719,35,5558,0.745570015,1.090362534,0.697201229,1.72433432,0.85479359,DB0113710000059_,0.156895254,0.086510241,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,98090,DB01377,10000059,44,3752,20,2650,0.125172993,1.553734871,0.894280907,2.789555488,0.248868735,DB0137710000059_,1.390829691,0.440661627,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,magnesium oxide,DB01377
,98094,DB09153,10000059,56,7743,35,5664,0.523288392,1.170365911,0.752666885,1.842547007,0.681597393,DB0915310000059_,0.383316129,0.157316445,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,98099,DB00425,10000060,92,12603,55,7429,0.93189554,0.986006559,0.697527387,1.405125897,0.97284883,DB0042510000060_,0.027526574,-0.014092272,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,98104,DB01234,10000060,223,31402,173,32715,0.00400436,1.342902788,1.095415306,1.648593707,0.01709511,DB0123410000060_,4.068962813,0.294833531,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,98109,DB09140,10000060,93,3648,31,1767,0.08062756,1.453033489,0.954108548,2.267368775,0.179422127,DB0914010000060_,1.718013996,0.373653432,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,oxygen,DB09140
,98110,DB09153,10000060,56,7743,32,5667,0.280562466,1.280778261,0.814002141,2.046809626,0.444399314,DB0915310000060_,0.811031764,0.24746791,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,98111,DB00121,10000081,67,4156,6,462,0.843110486,1.241243765,0.537175456,3.521873677,0.920371249,DB0012110000081_,0.082978159,0.216113913,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,biotin,DB00121
,98116,DB00512,10000081,74,4663,54,5044,0.032296948,1.48226925,1.027209608,2.150922583,0.089752634,DB0051210000081_,2.410697902,0.39357419,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,vancomycin,DB00512
,98123,DB00121,10002034,53,4170,12,456,0.033657578,0.483070539,0.252527952,1.000774239,0.09269616,DB0012110002034_,2.378428233,-0.727592592,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,biotin,DB00121
,98126,DB00668,10002034,38,10053,23,4280,0.206609242,0.703419181,0.407878562,1.238362041,0.357190471,DB0066810002034_,1.029486106,-0.351802291,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,epinephrine,DB00668
,98134,DB00121,10002855,84,4139,9,459,1,1.035026732,0.515407102,2.357768907,1,DB0012110002855_,0,0.034427255,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,biotin,DB00121
,98135,DB00218,10002855,41,1401,29,921,0.804610844,0.929439287,0.559261705,1.562668009,0.894419007,DB0021810002855_,0.111580926,-0.073173792,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,moxifloxacin,DB00218
,98137,DB00281,10002855,138,11320,63,5608,0.651127598,1.085168546,0.798384704,1.48882132,0.785609185,DB0028110002855_,0.24129583,0.081735317,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,lidocaine,DB00281
,98140,DB00512,10002855,36,4701,16,5082,0.003093951,2.432152897,1.313663263,4.700168503,0.013871982,DB0051210002855_,4.27788414,0.888776831,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,vancomycin,DB00512
,98141,DB00668,10002855,86,10005,29,4274,0.306830088,1.266782659,0.821621295,2.005325194,0.473911673,DB0066810002855_,0.746734318,0.236480347,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,epinephrine,DB00668
,98150,DB09153,10002855,97,7702,55,5644,0.137531614,1.292361984,0.917203406,1.836813908,0.266270281,DB0915310002855_,1.323243393,0.256471539,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,sodium chloride,DB09153
,98194,DB00264,10003445,54,29553,46,24846,1,0.986938471,0.653414031,1.496221094,1,DB0026410003445_,0,-0.013147581,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,98199,DB00338,10003445,86,33588,58,22214,0.932160649,0.980641106,0.694473051,1.39340166,0.972993348,DB0033810003445_,0.027378034,-0.019548731,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,98201,DB00404,10003445,41,19851,10,9852,0.051585121,2.034776488,1.001833114,4.557452537,0.128007071,DB0040410003445_,2.055669773,0.710385979,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,98203,DB00451,10003445,102,47169,27,15392,0.358711741,1.2327391,0.799633602,1.961262388,0.528442657,DB0045110003445_,0.63782098,0.209238604,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,98210,DB00864,10003445,30,6839,35,8357,0.900836372,1.047418431,0.620471678,1.758117831,0.956764412,DB0086410003445_,0.044198092,0.0463285,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,98212,DB00999,10003445,35,21395,20,12219,1,0.999450815,0.560961957,1.82798714,1,DB0099910003445_,0,-0.000549336,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,98213,DB01075,10003445,60,19888,17,11080,0.012105462,1.966265509,1.131520539,3.596461289,0.041423169,DB0107510003445_,3.183914925,0.676136063,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,98215,DB01234,10003445,66,31559,62,32826,0.59594635,1.107251094,0.770629775,1.59265344,0.741456274,DB0123410003445_,0.299139088,0.101880452,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,98230,DB00864,10003549,73,6796,77,8315,0.365875585,1.159941077,0.829042469,1.621714788,0.535455012,DB0086410003549_,0.624638403,0.148369208,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,98233,DB06723,10003549,50,980,31,579,0.90621892,0.952970184,0.589239495,1.562372846,0.958144782,DB0672310003549_,0.042756383,-0.048171662,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,aluminum hydroxide,DB06723
,98243,DB00682,10005364,33,19426,31,16333,0.707001023,0.895027826,0.531102616,1.511757529,0.824761313,DB0068210005364_,0.192661253,-0.110900471,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,warfarin,DB00682
,98290,DB00635,10007739,129,32924,70,23724,0.06111232,1.327897551,0.98462614,1.803598384,0.145494981,DB0063510007739_,1.927613687,0.283596902,NA,10007739,Cataract,10015919,Eye disorders,Eye,prednisone,DB00635
,98297,DB00904,10007739,69,23000,30,14426,0.098473648,1.442586079,0.926518541,2.295784771,0.208614131,DB0090410007739_,1.567268998,0.366437391,NA,10007739,Cataract,10015919,Eye disorders,Eye,ondansetron,DB00904
,98299,DB01075,10007739,45,19903,12,11085,0.025871952,2.088521274,1.085991901,4.339374311,0.075409654,DB0107510007739_,2.584819981,0.736456291,NA,10007739,Cataract,10015919,Eye disorders,Eye,diphenhydramine,DB01075
,98315,DB00381,10008629,54,29306,32,22855,0.232765518,1.316030013,0.834334588,2.10689328,0.389263027,DB0038110008629_,0.943500001,0.274619639,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,amlodipine,DB00381
,98318,DB00451,10008629,93,47178,31,15388,0.916964935,0.978506378,0.645157315,1.521261737,0.963037592,DB0045110008629_,0.037662832,-0.021727974,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,levothyroxine,DB00451
,98321,DB00635,10008629,54,32999,36,23758,0.74948911,1.07995701,0.695172834,1.695686821,0.858009244,DB0063510008629_,0.153140405,0.076921235,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,prednisone,DB00635
,98323,DB00682,10008629,38,19421,29,16335,0.714544678,1.102093788,0.661639092,1.853727199,0.830796075,DB0068210008629_,0.185370912,0.097211814,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,warfarin,DB00682
,98350,DB00682,10009802,107,19352,130,16234,0.0048451,0.690476624,0.529095427,0.899506927,0.019962919,DB0068210009802_,3.913878763,-0.37037316,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,warfarin,DB00682
,98355,DB00904,10009802,28,23041,32,14424,0.023325624,0.547791976,0.317660817,0.93959992,0.069636386,DB0090410009802_,2.664468056,-0.601859669,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,ondansetron,DB00904
,98360,DB01234,10009802,17,31608,41,32847,0.003472281,0.430920466,0.22947292,0.775553116,0.01522417,DB0123410009802_,4.184871013,-0.841831738,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,dexamethasone,DB01234
,98416,DB00338,10019660,39,33635,35,22237,0.192910324,0.736701667,0.454537533,1.198096727,0.340277681,DB0033810019660_,1.077993287,-0.305572263,NA,10019660,Hepatic encephalopathy,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,98448,DB00264,10019663,27,29580,39,24853,0.034921212,0.581687471,0.342329956,0.975049043,0.095277563,DB0026410019663_,2.350960927,-0.541821967,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,metoprolol,DB00264
,98452,DB00381,10019663,34,29326,35,22852,0.274920198,0.756986842,0.457898518,1.250159638,0.438142084,DB0038110019663_,0.825212028,-0.278409407,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,amlodipine,DB00381
,98457,DB00451,10019663,44,47227,22,15397,0.114672922,0.652047503,0.382355216,1.142735909,0.233142109,DB0045110019663_,1.456107101,-0.427637862,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,levothyroxine,DB00451
,98483,DB00316,10019708,57,65417,29,36924,0.736359545,1.109429787,0.697498917,1.799918611,0.847745865,DB0031610019708_,0.165174375,0.103846178,NA,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,98489,DB00451,10019708,62,47209,14,15405,0.232532376,1.445073734,0.799717376,2.796231579,0.388984503,DB0045110019708_,0.944215774,0.368160347,NA,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,levothyroxine,DB00451
,98492,DB00635,10019708,46,33007,16,23778,0.009907038,2.071089816,1.150564841,3.919897884,0.035287825,DB0063510019708_,3.344217285,0.72807495,NA,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,prednisone,DB00635
,98520,DB00512,10021036,36,4701,23,5075,0.050480506,1.689638468,0.972639622,2.991443312,0.125895924,DB0051210021036_,2.072299716,0.524514582,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,vancomycin,DB00512
,98522,DB00682,10021036,47,19412,45,16319,0.531902926,0.878032784,0.570535513,1.352677477,0.68875651,DB0068210021036_,0.372867466,-0.130071347,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,98526,DB01234,10021036,103,31522,103,32785,0.780643798,1.04007921,0.783374944,1.380822013,0.88061552,DB0123410021036_,0.127134161,0.039296873,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,98528,DB01377,10021036,33,3763,27,2643,0.599088744,0.858469824,0.499208227,1.488101775,0.743785166,DB0137710021036_,0.296003042,-0.152603749,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,magnesium oxide,DB01377
,98533,DB09153,10021036,102,7697,54,5645,0.060477215,1.385282249,0.984651569,1.967720393,0.144257326,DB0915310021036_,1.93615659,0.325903909,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,sodium chloride,DB09153
,98540,DB00316,10021137,52,65422,29,36924,1,1.012022837,0.630547483,1.653640927,1,DB0031610021137_,0,0.011951136,NA,10021137,Hypovolaemia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,98549,DB00451,10021137,34,47237,17,15402,0.145942338,0.652121165,0.354232994,1.245056532,0.278371202,DB0045110021137_,1.278799798,-0.427524899,NA,10021137,Hypovolaemia,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,98612,DB00121,10022437,90,4133,9,459,1,1.110564242,0.554720482,2.524201535,1,DB0012110022437_,0,0.104868212,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,biotin,DB00121
,98615,DB00281,10022437,117,11341,54,5617,0.743999462,1.073106536,0.769615163,1.512803727,0.853713896,DB0028110022437_,0.158159158,0.070557747,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,lidocaine,DB00281
,98618,DB00448,10022437,84,5061,31,3093,0.015455683,1.655907895,1.082014082,2.593809115,0.050463031,DB0044810022437_,2.986514274,0.504349435,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,lansoprazole,DB00448
,98621,DB00668,10022437,59,10032,17,4286,0.167844051,1.482748511,0.851429442,2.71659479,0.30793551,DB0066810022437_,1.177864901,0.393897467,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,epinephrine,DB00668
,98625,DB01075,10022437,260,19688,137,10960,0.63540862,1.05648348,0.854544888,1.310791879,0.773416276,DB0107510022437_,0.256937855,0.054945921,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,98626,DB01137,10022437,105,7667,64,5529,0.308320155,1.18309441,0.857103647,1.643982927,0.475626226,DB0113710022437_,0.743122973,0.168133387,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,levofloxacin,DB01137
,98632,DB09140,10022437,93,3648,36,1762,0.295597855,1.247675625,0.836850959,1.896004273,0.461434529,DB0914010022437_,0.7734151,0.22128232,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,oxygen,DB09140
,98662,DB00316,10022680,36,65438,19,36934,0.888814032,1.069417788,0.597270847,1.97399688,0.953896257,DB0031610022680_,0.047200359,0.067114377,NA,10022680,Intestinal ischaemia,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,98699,DB00338,10023126,27,33647,37,22235,0.004563378,0.482227535,0.282315466,0.813988824,0.018982178,DB0033810023126_,3.964254758,-0.729339212,NA,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,omeprazole,DB00338
,98714,DB01234,10023126,28,31597,42,32846,0.151097729,0.693026023,0.413578799,1.145011103,0.285408631,DB0123410023126_,1.253833331,-0.366687729,NA,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,dexamethasone,DB01234
,98754,DB00218,10033371,79,1363,46,904,0.512568258,1.138948234,0.773880753,1.692870522,0.672785032,DB0021810033371_,0.396329418,0.130105235,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,moxifloxacin,DB00218
,98757,DB00512,10033371,57,4680,44,5054,0.108990154,1.398924164,0.925456173,2.127062708,0.224540988,DB0051210033371_,1.493697014,0.335703487,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,98767,DB00425,10033557,116,12579,29,7455,1.28854864804101e-05,2.370524517,1.564989414,3.698666514,0.000135695,DB0042510033557_,8.905099975,0.863111246,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,zolpidem,DB00425
,98768,DB00448,10033557,40,5105,13,3111,0.047195802,1.874952729,0.980513424,3.827007792,0.11981858,DB0044810033557_,2.121776515,0.628583448,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,lansoprazole,DB00448
,98770,DB00668,10033557,78,10013,14,4289,0.001840685,2.386365756,1.338801688,4.570698879,0.009086752,DB0066810033557_,4.700937769,0.869771604,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,epinephrine,DB00668
,98775,DB01137,10033557,39,7733,13,5580,0.015905828,2.164617474,1.129796258,4.423824216,0.051608002,DB0113710033557_,2.964078548,0.77224366,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,levofloxacin,DB01137
,98777,DB01373,10033557,168,22552,20,7361,2.21548412971703e-06,2.741825847,1.718244427,4.606841708,2.90226764762582e-05,DB0137310033557_,10.44743309,1.008624066,female,10033557,Palpitations,10007541,Cardiac disorders,Card,calcium,DB01373
,98778,DB01377,10033557,43,3753,15,2655,0.015981872,2.027762871,1.101663511,3.937829889,0.051785443,DB0137710033557_,2.960646193,0.706933151,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,magnesium oxide,DB01377
,98790,DB00635,10033645,90,32963,89,23705,0.033764315,0.727234521,0.536186991,0.986487323,0.092911959,DB0063510033645_,2.376102912,-0.318506266,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,98792,DB00682,10033645,55,19404,36,16328,0.24850232,1.285577848,0.828989556,2.015883969,0.407885817,DB0068210033645_,0.896768005,0.251208304,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,98797,DB00864,10033645,19,6850,33,8359,0.264129119,0.702609464,0.377098679,1.273713569,0.426019937,DB0086410033645_,0.853269134,-0.35295407,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,98799,DB01075,10033645,39,19909,24,11073,0.694702862,0.903798889,0.529734376,1.571967873,0.816264204,DB0107510033645_,0.203017197,-0.101148411,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,98801,DB01234,10033645,45,31580,60,32828,0.240966884,0.779643709,0.517475168,1.16725038,0.399043286,DB0123410033645_,0.918685382,-0.248918247,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,98813,DB00404,10033661,39,19853,26,9836,0.237961576,0.743140967,0.440772625,1.272289528,0.395461704,DB0040410033661_,0.927701327,-0.296869526,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,alprazolam,DB00404
,98819,DB00813,10033661,50,10522,49,10119,1,0.981323821,0.647729703,1.487460394,1,DB0081310033661_,0,-0.018852781,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,fentanyl,DB00813
,98820,DB00864,10033661,71,6798,127,8265,0.009554886,0.679716719,0.500135561,0.91762224,0.034340627,DB0086410033661_,3.37142617,-0.386079157,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,tacrolimus,DB00864
,98822,DB01373,10033661,59,22661,37,7344,0.002693361,0.516760757,0.336643152,0.802628448,0.012381076,DB0137310033661_,4.391586117,-0.660175263,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,calcium,DB01373
,98823,DB01377,10033661,33,3763,37,2633,0.051315414,0.624125664,0.377200918,1.028758547,0.127476199,DB0137710033661_,2.059825609,-0.471403546,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,magnesium oxide,DB01377
,98872,DB00281,10035598,67,11391,42,5629,0.261119823,0.788340001,0.527418063,1.190241965,0.42265836,DB0028110035598_,0.861191085,-0.237825809,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,98879,DB00864,10035598,70,6799,96,8296,0.480922881,0.889739805,0.643195163,1.225593444,0.645627208,DB0086410035598_,0.437533019,-0.116826213,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tacrolimus,DB00864
,98881,DB01377,10035598,45,3751,36,2634,0.571786226,0.877785938,0.552020573,1.404783532,0.721925257,DB0137710035598_,0.325833668,-0.130352521,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium oxide,DB01377
,98887,DB00264,10036653,88,29519,68,24824,0.629680698,1.088317502,0.783689914,1.516879923,0.768748591,DB0026410036653_,0.262991293,0.084632928,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,98893,DB00682,10036653,132,19327,56,16308,9.25317470886055e-06,1.988870249,1.443352263,2.771815714,0.000101511,DB0068210036653_,9.1953461,0.687566763,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,98907,DB09140,10036653,58,3683,12,1786,0.004630381,2.343530606,1.240937834,4.806664984,0.019222291,DB0914010036653_,3.951684659,0.851658598,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,oxygen,DB09140
,98911,DB00281,10038695,104,11354,83,5588,0.001307664,0.616688562,0.456848361,0.834685153,0.006863408,DB0028110038695_,4.981551167,-0.483391145,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,98916,DB00864,10038695,158,6711,237,8155,0.045607475,0.810124513,0.65642378,0.997664012,0.116741102,DB0086410038695_,2.147796596,-0.210567324,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tacrolimus,DB00864
,98927,DB00338,10040831,55,33619,38,22234,0.832872626,0.957249307,0.621457219,1.488244269,0.913005963,DB0033810040831_,0.091012867,-0.043691412,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,98928,DB00381,10040831,57,29303,33,22854,0.201834821,1.347125759,0.862202928,2.136206728,0.351238558,DB0038110040831_,1.046289635,0.297973255,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,98934,DB00635,10040831,73,32980,34,23760,0.039035939,1.546805991,1.015964042,2.397912669,0.103731453,DB0063510040831_,2.265949907,0.436192154,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,98941,DB00904,10040831,38,23031,17,14439,0.269695026,1.401377536,0.771742772,2.648866371,0.432260702,DB0090410040831_,0.838726396,0.337455707,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,98944,DB01373,10040831,59,22661,18,7363,0.894961487,1.065000654,0.618975436,1.919961191,0.955976233,DB0137310040831_,0.045022227,0.062975413,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,98954,DB00264,10041101,47,29560,44,24848,0.673807248,0.897911202,0.582206769,1.387130987,0.802166018,DB0026410041101_,0.220439688,-0.1076841,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,98960,DB00451,10041101,80,47191,14,15405,0.030342694,1.865261931,1.049132107,3.565929165,0.085423629,DB0045110041101_,2.460132526,0.623401489,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,98966,DB00904,10041101,133,22936,65,14391,0.10719907,1.28381621,0.946570208,1.756137854,0.221920734,DB0090410041101_,1.505435014,0.249837056,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,98987,DB00635,10047531,40,33013,16,23778,0.056792156,1.800629397,0.985833519,3.44510426,0.137406279,DB0063510047531_,1.984813204,0.588136269,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,prednisone,DB00635
,99058,DB00635,10060795,125,32928,82,23712,0.526153278,1.097760891,0.823834202,1.469369389,0.684074735,DB0063510060795_,0.379688105,0.093272552,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,prednisone,DB00635
,99060,DB00682,10060795,51,19408,24,16340,0.01983373,1.789049114,1.080654299,3.040836692,0.061351064,DB0068210060795_,2.79114277,0.581684258,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,warfarin,DB00682
,99068,DB01234,10060795,71,31554,51,32837,0.046045639,1.448746093,0.996493004,2.119338565,0.117562858,DB0123410060795_,2.140782129,0.370698419,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,dexamethasone,DB01234
,99079,DB00281,10061428,129,11329,66,5605,0.818790591,0.967036528,0.712043711,1.323848764,0.903314125,DB0028110061428_,0.101684918,-0.033519009,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,lidocaine,DB00281
,99086,DB00916,10061428,47,5276,32,2399,0.087645311,0.667872902,0.416078555,1.084545068,0.191246637,DB0091610061428_,1.654191389,-0.403657389,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,metronidazole,DB00916
,99088,DB01377,10061428,96,3700,68,2602,1,0.992814204,0.717040986,1.38101414,1,DB0137710061428_,0,-0.007211738,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,magnesium oxide,DB01377
,99092,DB09140,10061428,150,3591,57,1741,0.130518333,1.275840861,0.929046863,1.772440381,0.256489431,DB0914010061428_,1.360667822,0.24360546,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,oxygen,DB09140
,99098,DB00404,10062237,46,19846,21,9841,0.796511687,1.086182345,0.63478409,1.917320174,0.889807667,DB0040410062237_,0.116749944,0.082669112,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,alprazolam,DB00404
,99099,DB00425,10062237,27,12668,32,7452,0.009672342,0.49634633,0.285846947,0.855922922,0.034658512,DB0042510062237_,3.362211924,-0.70048135,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,zolpidem,DB00425
,99100,DB00448,10062237,48,5097,46,3078,0.031803503,0.630202461,0.410607696,0.968138114,0.088662574,DB0044810062237_,2.422917423,-0.461714145,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,lansoprazole,DB00448
,99101,DB00451,10062237,158,47113,87,15332,0.000137877,0.591017701,0.451835414,0.777415098,0.001049091,DB0045110062237_,6.859831031,-0.525909311,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,99107,DB00813,10062237,30,10542,27,10141,0.894630449,1.068871291,0.61364096,1.870129522,0.955976233,DB0081310062237_,0.045022227,0.066603223,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,fentanyl,DB00813
,99108,DB00864,10062237,88,6781,92,8300,0.29270419,1.170775701,0.862424648,1.588549244,0.458287446,DB0086410062237_,0.78025868,0.157666521,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,tacrolimus,DB00864
,99111,DB01137,10062237,32,7740,22,5571,0.891182717,1.046937191,0.589019208,1.893421289,0.954816394,DB0113710062237_,0.046236214,0.045868941,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,levofloxacin,DB01137
,99112,DB01234,10062237,112,31513,181,32707,0.000215543,0.642237204,0.50255663,0.817773955,0.001534756,DB0123410062237_,6.479383759,-0.442797566,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,dexamethasone,DB01234
,99114,DB01373,10062237,67,22653,28,7353,0.281926157,0.776711167,0.492409553,1.255244021,0.445887603,DB0137310062237_,0.807688369,-0.252686726,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,calcium,DB01373
,99122,DB00331,10000060,170,24776,93,20659,0.000978437,1.524190081,1.176024934,1.985723577,0.005409865,DB0033110000060_,5.219531073,0.421463174,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,99134,DB01261,10003988,76,3705,66,3237,1,1.006059957,0.711310322,1.42604669,1,DB0126110003988_,0,0.006041669,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sitagliptin,DB01261
,99139,DB01067,10012378,48,4313,39,4784,0.161378466,1.36512063,0.874143809,2.14373722,0.29931816,DB0106710012378_,1.206248191,0.311242798,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,glipizide,DB01067
,99154,DB00641,10049438,41,14083,34,12441,0.817553691,1.065301201,0.659145392,1.731840064,0.902479843,DB0064110049438_,0.102608924,0.063257577,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,99155,DB01136,10049438,26,9858,30,11085,1,0.97453612,0.553233184,1.706077321,1,DB0113610049438_,0,-0.025793695,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,99167,DB01136,10061024,94,9790,142,10973,0.025772578,0.741974964,0.564714096,0.971135198,0.07519505,DB0113610061024_,2.587669871,-0.298439778,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,carvedilol,DB01136
,99168,DB00331,10003119,33,24913,50,20702,0.007809034,0.548455878,0.342151186,0.868652202,0.029210256,DB0033110003119_,3.533235403,-0.600648443,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,metformin,DB00331
,99169,DB00331,10038428,74,24872,80,20672,0.105495584,0.768809396,0.552417524,1.068708648,0.219353038,DB0033110038428_,1.517072801,-0.2629122,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,99172,DB06724,10002034,186,7743,98,3821,0.609872001,0.936607347,0.727067972,1.212607067,0.75213743,DB0672410002034_,0.284836219,-0.065491138,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,calcium carbonate,DB06724
,99173,DB00421,10012735,663,8240,261,4991,4.64327455629459e-09,1.538581317,1.325336284,1.790125144,1.12331773320021e-07,DB0042110012735_,16.00180908,0.430860769,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,99174,DB00887,10017955,45,2296,51,1764,0.06146431,0.677979913,0.441485447,1.037992422,0.146154277,DB0088710017955_,1.92309252,-0.388637618,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,bumetanide,DB00887
,99175,DB00904,10017955,135,22934,100,14356,0.202241384,0.845069135,0.647098316,1.106667359,0.351657843,DB0090410017955_,1.045096612,-0.168336839,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,99176,DB06724,10017955,54,7875,39,3880,0.076462714,0.682202937,0.442722156,1.059868007,0.172265574,DB0672410017955_,1.75871796,-0.382428104,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,99177,DB00203,10018836,64,13814,34,8904,0.407215033,1.213256674,0.787671876,1.898833829,0.576751739,DB0020310018836_,0.550343367,0.19330821,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,99178,DB00421,10018836,40,8863,30,5222,0.323172067,0.785615428,0.476550592,1.307868059,0.491584362,DB0042110018836_,0.710121712,-0.241287884,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,99212,DB00421,10066152,69,8834,24,5228,0.023690997,1.70137746,1.054092719,2.835259914,0.070522975,DB0042110066152_,2.651816743,0.531438193,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,spironolactone,DB00421
,99214,DB00761,10066152,74,15233,27,8598,0.060979577,1.546936333,0.982650267,2.502892223,0.145275801,DB0076110066152_,1.929121264,0.436276416,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,potassium chloride,DB00761
,99217,DB00904,10066152,47,23022,19,14437,0.128123635,1.551218917,0.892681834,2.800056029,0.253013016,DB0090410066152_,1.374314346,0.43904102,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,ondansetron,DB00904
,99219,DB09140,10066152,75,3666,18,1780,0.006980459,2.022871651,1.192708943,3.60810587,0.026729023,DB0914010066152_,3.622005318,0.704518111,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,oxygen,DB09140
,99234,DB00331,10012373,36,24910,54,20698,0.005779532,0.553955425,0.352769329,0.860594953,0.022980865,DB0033110012373_,3.773093381,-0.590671056,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,metformin,DB00331
,99258,DB00924,10022004,68,10094,12,4239,0.004311235,2.379614242,1.275995104,4.835306663,0.018153112,DB0092410022004_,4.008913259,0.866938391,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,99259,DB00959,10022004,44,8034,11,4991,0.005048248,2.484781897,1.261294172,5.340365524,0.020618949,DB0095910022004_,3.881544783,0.910184888,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,99263,DB00959,10028334,125,7953,46,4956,0.001951601,1.693307151,1.196216737,2.433821041,0.009545557,DB0095910028334_,4.651679471,0.526683511,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,methylprednisolone,DB00959
,99269,DB00476,10043607,86,17171,53,6124,0.002594341,0.578728245,0.405745619,0.832129261,0.012008848,DB0047610043607_,4.422111529,-0.546922264,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,duloxetine,DB00476
,99271,DB00924,10048393,79,10083,10,4241,5.78560842886846e-05,3.322280162,1.71283282,7.205275131,0.000500164,DB0092410048393_,7.600575478,1.200651343,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,99272,DB00476,10051055,58,17199,46,6131,7.92514959506487e-05,0.449478305,0.299634338,0.67773275,0.000653816,DB0047610051055_,7.332684137,-0.799667692,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,duloxetine,DB00476
,99279,DB00404,10010071,79,19813,28,9834,0.149329893,1.400381721,0.898973521,2.240582103,0.2830457,DB0040410010071_,1.262146909,0.336744857,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,99291,DB01104,10007617,177,15286,81,7205,0.893263492,1.030007421,0.786227093,1.35897795,0.955497126,DB0110410007617_,0.045523523,0.029566007,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,sertraline,DB01104
,99320,DB01593,10003988,43,1090,10,688,0.003677744,2.712843227,1.331295322,6.094655142,0.015948115,DB0159310003988_,4.138414652,0.997997246,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,zinc,DB01593
,99321,DB01593,10012735,101,1032,31,667,0.000264586,2.104954032,1.376944367,3.297740818,0.001821061,DB0159310012735_,6.308336116,0.744293629,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,zinc,DB01593
,99322,DB01373,10013946,173,22547,44,7337,0.154334674,1.279429397,0.913288121,1.82640865,0.289939385,DB0137310013946_,1.238083395,0.246414195,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,99324,DB14513,10013946,66,7111,20,3544,0.050917803,1.64459367,0.982708323,2.868933869,0.126734005,DB1451310013946_,2.065664834,0.497493344,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,99326,DB01373,10017853,46,22674,9,7372,0.208332343,1.661693947,0.803167933,3.863379603,0.359212545,DB0137310017853_,1.02384102,0.507837532,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,99329,DB01069,10047942,80,6620,30,2365,0.82779034,0.952670672,0.617217376,1.50587541,0.9094639,DB0106910047942_,0.094899974,-0.048486005,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,promethazine,DB01069
,99331,DB14513,10047942,145,7032,54,3510,0.068522617,1.340287985,0.971432161,1.872611719,0.158639803,DB1451310047942_,1.841119039,0.292884505,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,magnesium,DB14513
,99333,DB01373,10057362,58,22662,14,7367,0.410001224,1.346738431,0.741365714,2.616182419,0.579402268,DB0137310057362_,0.545758279,0.297685692,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,99345,DB00722,10007554,80,25323,116,25916,0.018004952,0.705812718,0.52380915,0.947059069,0.056858312,DB0072210007554_,2.867192862,-0.348405349,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,lisinopril,DB00722
,99352,DB00381,10014387,92,29268,78,22809,0.588749385,0.919194385,0.672058949,1.259920948,0.735582809,DB0038110014387_,0.307092157,-0.084257661,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,amlodipine,DB00381
,99353,DB00682,10014387,34,19425,38,16326,0.237897484,0.752004555,0.458984082,1.227613941,0.395392688,DB0068210014387_,0.927875861,-0.285012898,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,warfarin,DB00682
,99354,DB00761,10014387,38,15269,28,8597,0.304791746,0.764148302,0.456402319,1.293712813,0.471566957,DB0076110014387_,0.751694178,-0.268993395,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,potassium chloride,DB00761
,99357,DB01068,10014387,85,13678,24,6816,0.013990572,1.764833874,1.109670148,2.90679548,0.046561432,DB0106810014387_,3.066982725,0.568056564,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,clonazepam,DB01068
,99358,DB01136,10014387,37,9847,34,11081,0.406762616,1.224594778,0.747099667,2.012912436,0.576297284,DB0113610014387_,0.551131634,0.202609995,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,carvedilol,DB01136
,99389,DB00448,10007559,30,5115,21,3103,0.664481719,0.866658237,0.478979331,1.595599139,0.795785584,DB0044810007559_,0.228425496,-0.14311057,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,lansoprazole,DB00448
,99397,DB01233,10011906,186,3235,139,1587,0.00033521,0.656487732,0.5196966,0.830804607,0.002212431,DB0123310011906_,6.11366344,-0.420851273,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,99400,DB01233,10020772,57,3364,25,1701,0.637531712,1.152834423,0.705814259,1.932901357,0.77479533,DB0123310020772_,0.255156375,0.142223626,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,metoclopramide,DB01233
,99421,DB01195,10016173,42,1197,21,723,0.511860864,1.207872669,0.692966622,2.165496453,0.672160972,DB0119510016173_,0.397257426,0.188860688,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,flecainide,DB01195
,99445,DB00316,10001488,70,65404,63,36890,0.008546181,0.626676587,0.439378419,0.895488293,0.031393647,DB0031610001488_,3.461149729,-0.467324682,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,99447,DB00321,10001497,45,7402,25,2825,0.140606768,0.687003617,0.411472218,1.171429295,0.270688754,DB0032110001497_,1.306785629,-0.375415723,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,amitriptyline,DB00321
,99454,DB00927,10007515,67,7430,68,4948,0.016871634,0.656195973,0.460258095,0.935275255,0.054085114,DB0092710007515_,2.917196295,-0.421295796,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,famotidine,DB00927
,99457,DB00404,10020919,51,19841,10,9852,0.004136146,2.532323098,1.270523524,5.596794683,0.017553662,DB0040410020919_,4.042492678,0.929137102,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,alprazolam,DB00404
,99458,DB00722,10020919,71,25332,71,25961,0.933078142,1.024834601,0.726688476,1.44529049,0.973754674,DB0072210020919_,0.026595882,0.024531235,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,99459,DB00758,10020919,42,8258,38,10036,0.215484108,1.343201215,0.844454924,2.142847903,0.367981827,DB0075810020919_,0.999721726,0.295055732,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,clopidogrel,DB00758
,99460,DB00761,10020919,201,15106,93,8532,0.126380989,1.220661082,0.948591852,1.580509279,0.250624894,DB0076110020919_,1.383797904,0.199392583,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,99461,DB00927,10020919,52,7445,25,4991,0.199508011,1.394359747,0.848459069,2.3483744,0.348466216,DB0092710020919_,1.054213995,0.332435347,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,famotidine,DB00927
,99462,DB01136,10020919,82,9802,77,11038,0.26481127,1.19920678,0.866752211,1.660621893,0.426757033,DB0113610020919_,0.851540437,0.181660321,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,carvedilol,DB01136
,99464,DB00404,10016807,126,19766,24,9838,3.07715291627599e-06,2.612974149,1.677666462,4.232500001,3.87463302535638e-05,DB0040410016807_,10.15847451,0.960489093,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,alprazolam,DB00404
,99465,DB00927,10016807,56,7441,24,4992,0.067641249,1.565326225,0.952969686,2.644635814,0.157097436,DB0092710016807_,1.850889054,0.448094253,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,famotidine,DB00927
,99468,DB00695,10042604,56,27993,24,20504,0.030822677,1.70907012,1.041699226,2.884312216,0.08654319,DB0069510042604_,2.447111687,0.535949433,NA,10042604,Supraventricular tachycardia,10007541,Cardiac disorders,Card,furosemide,DB00695
,99509,DB01098,10021015,39,8110,20,7189,0.049731824,1.728485642,0.982877192,3.131108084,0.124524981,DB0109810021015_,2.083248934,0.547245674,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,rosuvastatin,DB01098
,99523,DB01098,10043554,50,8099,46,7163,0.918371174,0.961325233,0.630274545,1.469218969,0.963904799,DB0109810043554_,0.036762745,-0.039442496,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,rosuvastatin,DB01098
,99527,DB01136,10047302,9,9875,48,11067,8.57491639731044e-07,0.210150007,0.090592209,0.43331091,1.25182825605834e-05,DB0113610047302_,11.28832038,-1.559933683,male,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,carvedilol,DB01136
,99535,DB00524,10061818,34,1543,19,1325,0.163982395,1.536427037,0.847224405,2.865847289,0.302736576,DB0052410061818_,1.194892236,0.429459615,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,99538,DB01098,10061818,42,8107,61,7148,0.013155633,0.607103107,0.399201181,0.915460313,0.044312912,DB0109810061818_,3.11647918,-0.49905664,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,99539,DB00627,10013709,49,1280,47,1552,0.297290064,1.263987133,0.823610702,1.941781407,0.463192545,DB0062710013709_,0.769612448,0.234271116,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,niacin,DB00627
,99540,DB00635,10013781,169,32884,55,23739,8.83530028513727e-08,2.218157641,1.626476026,3.066204335,1.61780472305701e-06,DB0063510013781_,13.33444044,0.79667696,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,99542,DB01240,10005724,100,5651,8,1568,0.000126054,3.468071903,1.688843338,8.271705672,0.000972652,DB0124010005724_,6.935484155,1.243598792,female,10005724,Blood potassium decreased,10022891,Investigations,Inv,epoprostenol,DB01240
,99552,DB00559,10040753,117,9542,21,3285,0.004290511,1.918067393,1.195972794,3.219929438,0.018083232,DB0055910040753_,4.012770163,0.651318113,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,bosentan,DB00559
,99553,DB00203,10040880,39,13839,13,8925,0.045404852,1.93469366,1.010280654,3.952843527,0.116357296,DB0020310040880_,2.151089682,0.659948999,NA,10040880,Skin irritation,10040785,Skin and subcutaneous tissue disorders,Skin,sildenafil,DB00203
,99555,DB01240,10040880,71,5680,13,1563,0.228244816,1.502790519,0.822355666,2.967800279,0.3837156,DB0124010040880_,0.957853625,0.407323726,NA,10040880,Skin irritation,10040785,Skin and subcutaneous tissue disorders,Skin,epoprostenol,DB01240
,99560,DB00203,10060800,89,13789,25,8913,0.000105663,2.30104582,1.461282934,3.746541845,0.000836564,DB0020310060800_,7.086207254,0.833363724,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,sildenafil,DB00203
,99601,DB00213,10029148,57,18838,46,13375,0.548452561,0.8797894,0.585707481,1.327840363,0.702872554,DB0021310029148_,0.352579693,-0.128072718,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,99602,DB00451,10029148,153,47118,56,15363,0.469106871,0.890813087,0.651502066,1.233281445,0.635444052,DB0045110029148_,0.45343123,-0.115620652,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,99604,DB01098,10029148,31,8118,24,7185,0.685603091,1.143205324,0.648747714,2.037688742,0.810172735,DB0109810029148_,0.210507801,0.133836004,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,rosuvastatin,DB01098
,99630,DB00451,10043224,70,47201,18,15401,0.457021761,1.268874403,0.747192833,2.264726425,0.624343652,DB0045110043224_,0.471054338,0.238130211,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,99636,DB00843,10046571,95,2099,54,2119,0.000818383,1.77578058,1.250986798,2.542603853,0.0046657,DB0084310046571_,5.367517432,0.57424009,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,donepezil,DB00843
,99652,DB00333,10013709,101,2970,84,3068,0.15633488,1.242009204,0.91636608,1.686964281,0.292498909,DB0033310013709_,1.229294341,0.216730394,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,methadone,DB00333
,99654,DB01233,10013709,115,3306,47,1679,0.236753986,1.242551717,0.872860661,1.793307901,0.394052779,DB0123310013709_,0.931270421,0.217167101,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,99671,DB00175,10003285,40,8091,14,6092,0.012648571,2.151114967,1.144544783,4.284660608,0.042935066,DB0017510003285_,3.148066387,0.765986297,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,99672,DB00193,10003285,108,19212,30,8672,0.016522301,1.624958845,1.074794754,2.525427224,0.053133748,DB0019310003285_,2.934943002,0.485482489,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,99677,DB00476,10003285,88,17169,23,6154,0.195622396,1.371364786,0.857696489,2.276887001,0.343792645,DB0047610003285_,1.067716581,0.315806438,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,99679,DB00656,10003285,39,11974,17,6602,0.485469119,1.264908246,0.69833033,2.386502326,0.649524371,DB0065610003285_,0.43151492,0.234999587,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,99682,DB00175,10010264,143,7988,74,6032,0.008557708,1.459203415,1.092215797,1.963184303,0.031424888,DB0017510010264_,3.460155098,0.377890681,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,99685,DB00281,10010264,168,11290,67,5604,0.142746601,1.244572448,0.93050363,1.680934992,0.273645801,DB0028110010264_,1.295920707,0.218792055,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,99686,DB00650,10010264,33,2098,20,1994,0.128337293,1.568033629,0.870167931,2.894014605,0.253273199,DB0065010010264_,1.373286535,0.449822369,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,leucovorin,DB00650
,99688,DB08895,10010264,1740,26374,369,6277,0.0520289,1.122269846,0.998950681,1.26333674,0.128852841,DB0889510010264_,2.049084292,0.115353282,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,99691,DB00275,10013709,103,1957,61,1176,1,1.01466382,0.725740138,1.428642855,1,DB0027510013709_,0,0.014557346,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,olmesartan,DB00275
,99700,DB00335,10020100,35,8431,22,5443,1,1.027080435,0.585172946,1.840003475,1,DB0033510020100_,0,0.026720249,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,atenolol,DB00335
,99701,DB00338,10020100,146,33528,47,22225,8.32224775293904e-06,2.059122972,1.472230675,2.926294949,9.25927120364032e-05,DB0033810020100_,9.287300123,0.722280151,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,99702,DB00761,10020100,57,15250,27,8598,0.496030475,1.190214253,0.739945267,1.958892824,0.658376603,DB0076110020100_,0.417978167,0.174133335,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,99705,DB00115,10002948,41,18384,17,10455,0.338476512,1.371558687,0.761763289,2.5762631,0.50752299,DB0011510002948_,0.678213269,0.315947821,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,99707,DB00338,10002948,61,33613,33,22239,0.399232633,1.222966498,0.787807159,1.929367023,0.569079705,DB0033810002948_,0.563734775,0.201279463,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,99709,DB00381,10002948,54,29306,30,22857,0.152592255,1.403886029,0.882140838,2.273296554,0.287590968,DB0038110002948_,1.246216059,0.339244126,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,99710,DB00635,10002948,39,33014,32,23762,0.630674786,0.877205722,0.535367043,1.446891856,0.76955118,DB0063510002948_,0.261947817,-0.13101374,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,99714,DB00904,10002948,82,22987,34,14422,0.044585813,1.513119959,1.002369788,2.329607854,0.114744025,DB0090410002948_,2.165051497,0.414173717,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,99720,DB08875,10020772,26,617,37,1206,0.225941971,1.373331677,0.790553306,2.354096769,0.380822981,DB0887510020772_,0.96542063,0.317239668,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,cabozantinib,DB08875
,99722,DB08868,10008469,111,9091,21,2490,0.13515488,1.44768611,0.900107361,2.436174096,0.262888669,DB0886810008469_,1.336024648,0.369966495,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,99723,DB08868,10020642,49,9153,18,2493,0.295355376,0.741471743,0.423402727,1.354955013,0.461283957,DB0886810020642_,0.773741466,-0.299118226,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,fingolimod,DB08868
,99724,DB00820,10018627,44,11871,39,5777,0.006961808,0.54903155,0.348196428,0.868723322,0.026684157,DB0082010018627_,3.623685253,-0.59959937,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,tadalafil,DB00820
,99725,DB06403,10018627,42,21429,27,6634,0.004190862,0.481569281,0.28981707,0.812926379,0.017741592,DB0640310018627_,4.031843548,-0.730705172,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,ambrisentan,DB06403
,99726,DB06403,10019974,37,21434,13,6648,0.738989436,0.882754454,0.458280296,1.810965087,0.84982007,DB0640310019974_,0.162730635,-0.124708199,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,99743,DB00515,10042772,35,1835,25,2126,0.068609154,1.621802701,0.939396224,2.838322314,0.158791196,DB0051510042772_,1.840165173,0.483538309,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,cisplatin,DB00515
,99747,DB00186,10047340,67,16834,25,9983,0.051462578,1.589283364,0.989744475,2.628374296,0.127751227,DB0018610047340_,2.057670447,0.4632832,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,lorazepam,DB00186
,99750,DB00904,10047340,102,22967,28,14428,4.20258026434979e-05,2.288411215,1.492986112,3.614218116,0.000380716,DB0090410047340_,7.87345619,0.827857784,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,ondansetron,DB00904
,99751,DB01104,10047340,61,15402,24,7262,0.486836008,1.198362287,0.735523068,2.011648223,0.650707303,DB0110410047340_,0.42969535,0.180955864,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,sertraline,DB01104
,99775,DB00762,10035664,24,1139,32,1337,0.685625063,0.880427523,0.493102439,1.552544159,0.810180489,DB0076210035664_,0.21049823,-0.127347668,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,irinotecan,DB00762
,99778,DB00661,10048959,68,3460,13,1582,0.002362652,2.391305322,1.304481212,4.733338272,0.011143425,DB0066110048959_,4.496905653,0.871839377,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,verapamil,DB00661
,99781,DB01015,10051055,58,9829,121,9260,3.61452527925804e-07,0.451605728,0.323963459,0.623428947,5.77379501460332e-06,DB0101510051055_,12.06218098,-0.794945763,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,sulfamethoxazole,DB01015
,99787,DB00836,10041101,30,5505,20,4055,0.77571984,1.104922313,0.606057994,2.055972592,0.877814798,DB0083610041101_,0.130319644,0.099775028,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,99792,DB00758,10017944,29,8271,34,10040,0.899765341,1.035380428,0.60796439,1.752645015,0.956571579,DB0075810017944_,0.044399659,0.034768922,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,99793,DB00758,10038153,24,8276,41,10033,0.211919458,0.709653614,0.409786349,1.203808396,0.363691757,DB0075810038153_,1.011448591,-0.342978296,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,clopidogrel,DB00758
,99803,DB00390,10008469,55,4090,20,3281,0.002180589,2.205794932,1.298001027,3.893957528,0.010445924,DB0039010008469_,4.561543378,0.791087957,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,99804,DB00421,10008469,128,8775,38,5214,9.59614445447694e-05,2.001384262,1.381223464,2.960535645,0.000769125,DB0042110008469_,7.170256604,0.693839072,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,99805,DB00695,10008469,293,27756,129,20399,8.57356592087789e-07,1.669260533,1.35130991,2.071372256,1.25182825605834e-05,DB0069510008469_,11.28832038,0.512380734,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,99806,DB00761,10008469,129,15178,49,8576,0.018543413,1.487500033,1.061546223,2.11379104,0.058216018,DB0076110008469_,2.843594739,0.39709688,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,99807,DB01076,10008469,159,25588,123,25460,0.036705894,1.28620683,1.009399374,1.642195855,0.098968431,DB0107610008469_,2.312954356,0.251697445,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,99808,DB01136,10008469,81,9803,50,11065,0.000793346,1.828481418,1.268321763,2.658838058,0.004544147,DB0113610008469_,5.393915179,0.603485796,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,99812,DB00184,10013968,54,1240,37,945,0.666557334,1.112162334,0.711949265,1.754037565,0.797290536,DB0018410013968_,0.22653613,0.106306169,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nicotine,DB00184
,99813,DB00184,10016256,43,1251,41,941,0.312868234,0.78898002,0.497755685,1.252143439,0.480386794,DB0018410016256_,0.733163679,-0.237014282,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,nicotine,DB00184
,99815,DB00184,10021097,34,1260,16,966,0.114248753,1.628830489,0.8688893,3.179852394,0.232504527,DB0018410021097_,1.458845582,0.487862266,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,nicotine,DB00184
,99816,DB00222,10021097,33,3173,54,3074,0.017631128,0.592096538,0.370802607,0.932728989,0.055990602,DB0022210021097_,2.882571424,-0.524085586,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,glimepiride,DB00222
,99817,DB01261,10021097,44,3737,70,3233,0.001689286,0.543850368,0.36313416,0.806807228,0.008463334,DB0126110021097_,4.772012116,-0.609081129,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sitagliptin,DB01261
,99823,DB00295,10001053,60,14603,75,9527,0.000189732,0.521923059,0.364986757,0.743626786,0.001378793,DB0029510001053_,6.586546746,-0.650235098,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,99825,DB01222,10001053,79,9195,64,5341,0.054980712,0.717037721,0.508197387,1.014947243,0.134309296,DB0122210001053_,2.007609962,-0.33262683,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,99849,DB00734,10013700,74,3976,25,4877,2.6507835512051e-09,3.63027187,2.274438197,5.975239059,6.77451100081927e-08,DB0073410013700_,16.50751356,1.289307541,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,risperidone,DB00734
,99850,DB08893,10013968,60,2025,26,1032,0.56340716,1.17599003,0.725773032,1.954042923,0.71536668,DB0889310013968_,0.334960029,0.162110371,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mirabegron,DB08893
,99851,DB00193,10022004,90,19230,27,8675,0.071020171,1.503714533,0.967928737,2.407334403,0.163071867,DB0019310022004_,1.813564272,0.407938402,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,99852,DB00215,10022004,64,11039,16,5260,0.021982238,1.905903684,1.087711033,3.535838137,0.066590197,DB0021510022004_,2.70919791,0.644956271,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,99853,DB00425,10022004,98,12597,30,7454,0.00123119,1.932919183,1.271207265,3.018085839,0.006532464,DB0042510022004_,5.030971005,0.65903139,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,99856,DB01115,10005483,31,3569,27,2241,0.224381587,0.720989036,0.415155823,1.259222493,0.379003953,DB0111510005483_,0.970208643,-0.327131348,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,nifedipine,DB01115
,99862,DB00275,10010774,67,1993,38,1199,0.837939293,1.060713557,0.697132018,1.634498206,0.916610526,DB0027510010774_,0.087072624,0.058941848,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,olmesartan,DB00275
,99863,DB01162,10010774,9,264,49,1653,0.698830612,1.149931461,0.490708026,2.401860399,0.818973767,DB0116210010774_,0.199703226,0.139702342,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,terazosin,DB01162
,99864,DB08889,10010774,54,3111,52,3833,0.237647815,1.279414577,0.855173334,1.915591732,0.395115141,DB0888910010774_,0.92857806,0.246402611,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,carfilzomib,DB08889
,99869,DB01234,10013036,40,31585,24,32864,0.033446576,1.734129178,1.019926577,3.008238779,0.092239725,DB0123410013036_,2.38336438,0.550505373,NA,10013036,Diplopia,10015919,Eye disorders,Eye,dexamethasone,DB01234
,99872,DB01162,10013968,16,257,71,1631,0.204520533,1.429859228,0.763259319,2.532762018,0.354535528,DB0116210013968_,1.036946719,0.357575998,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,terazosin,DB01162
,99873,DB00275,10016256,110,1950,75,1162,0.390601038,0.87402302,0.639661377,1.199437963,0.560453534,DB0027510016256_,0.579008941,-0.134648565,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,olmesartan,DB00275
,99874,DB01162,10016256,14,259,107,1595,0.585936061,0.805842138,0.41963636,1.439304777,0.733239513,DB0116210016256_,0.310282873,-0.215867415,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,terazosin,DB01162
,99875,DB04861,10016256,137,1828,98,1289,0.945276673,0.985760794,0.747342887,1.304044466,0.983867798,DB0486110016256_,0.016263743,-0.014341557,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,nebivolol,DB04861
,99879,DB08889,10018884,51,3114,60,3825,0.847792212,1.044091349,0.702177107,1.547271987,0.923872577,DB0888910018884_,0.07918112,0.043146985,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,carfilzomib,DB08889
,99881,DB04861,10020772,42,1923,33,1354,0.637537029,0.896168629,0.551340603,1.467593803,0.77479533,DB0486110020772_,0.255156375,-0.109626682,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,nebivolol,DB04861
,99882,DB00275,10022437,43,2017,17,1220,0.177820421,1.529750506,0.850013841,2.874363697,0.321094836,DB0027510022437_,1.136018759,0.425104654,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,olmesartan,DB00275
,99883,DB01115,10022437,59,3541,20,2248,0.014369462,1.872617529,1.107668317,3.292801276,0.047590413,DB0111510022437_,3.045123937,0.6273372,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,nifedipine,DB01115
,99884,DB04861,10022437,31,1934,19,1368,0.666658341,1.154005552,0.628679772,2.171766658,0.797361892,DB0486110022437_,0.226446636,0.14323898,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,nebivolol,DB04861
,99885,DB08889,10022437,59,3106,68,3817,0.719888822,1.066231258,0.736837229,1.539092487,0.834674324,DB0888910022437_,0.180713661,0.064130242,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,carfilzomib,DB08889
,99886,DB00275,10046571,39,2021,18,1219,0.408541307,1.306758933,0.726170359,2.438362539,0.577960616,DB0027510046571_,0.548249551,0.267549975,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,olmesartan,DB00275
,99888,DB08889,10046571,42,3123,19,3866,0.000229891,2.736064232,1.552908168,4.991198939,0.001619372,DB0888910046571_,6.425716763,1.006520476,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,carfilzomib,DB08889
,99891,DB00193,10061024,71,19249,64,8638,7.68026133155346e-05,0.49782947,0.349715282,0.709910677,0.000635929,DB0019310061024_,7.360423596,-0.69749769,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,tramadol,DB00193
,99892,DB01015,10061024,24,9863,42,9339,0.018492348,0.541090896,0.313121636,0.915174571,0.058083452,DB0101510061024_,2.845874467,-0.614167999,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,sulfamethoxazole,DB01015
,99901,DB00480,10061368,66,67362,94,67568,0.032413212,0.70427975,0.506046102,0.975329708,0.089994853,DB0048010061368_,2.408002797,-0.350579629,NA,10061368,Spinal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,99902,DB05676,10062355,310,46819,179,25150,0.446703695,0.930305245,0.770980419,1.125328222,0.614454269,DB0567610062355_,0.487020772,-0.072242527,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,99913,DB00341,10037884,58,11347,20,5048,0.389460442,1.290083193,0.763514377,2.267217635,0.559377907,DB0034110037884_,0.580929992,0.254706707,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,cetirizine,DB00341
,99925,DB01042,10029354,55,935,59,1269,0.244062364,1.26506403,0.851162119,1.877781992,0.40257157,DB0104210029354_,0.909882385,0.235122738,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,melphalan,DB01042
,99930,DB01042,10053762,35,955,52,1276,0.660086025,0.899325689,0.563713445,1.419913609,0.792471049,DB0104210053762_,0.232599305,-0.106110031,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,melphalan,DB01042
,99931,DB00678,10046735,144,15455,75,10649,0.053067968,1.322928316,0.992784967,1.775059284,0.130760867,DB0067810046735_,2.034385066,0.2798477,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,99936,DB00331,10002544,42,24904,13,20739,0.00103048,2.690309977,1.416227856,5.46360905,0.005646898,DB0033110002544_,5.176648842,0.98965642,NA,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,99940,DB00715,10008190,30,4813,20,2267,0.227263151,0.706543903,0.387233824,1.315764439,0.382519254,DB0071510008190_,0.96097629,-0.347369937,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,paroxetine,DB00715
,99941,DB01069,10008190,50,6650,24,2371,0.2342402,0.742820502,0.446865027,1.266803446,0.391107109,DB0106910008190_,0.938773821,-0.297300849,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,99942,DB01229,10008190,40,5701,24,2685,0.349037269,0.784999919,0.460719343,1.364330756,0.518549928,DB0122910008190_,0.656718962,-0.242071664,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,paclitaxel,DB01229
,99943,DB11089,10008190,100,10075,98,8309,0.25075341,0.841555659,0.629481678,1.125290897,0.410567999,DB1108910008190_,0.890213714,-0.172503124,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,docusate,DB11089
,99946,DB01229,10010305,47,5694,30,2679,0.219530993,0.737114282,0.455397558,1.21006956,0.372883499,DB0122910010305_,0.986489243,-0.305012335,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,paclitaxel,DB01229
,99947,DB01233,10010305,39,3382,30,1696,0.094372446,0.651961699,0.393174414,1.09091465,0.202339388,DB0123310010305_,1.597808851,-0.427769463,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,metoclopramide,DB01233
,99949,DB00334,10012174,35,2814,24,2788,0.190763226,1.444759379,0.83288037,2.54590994,0.337509602,DB0033410012174_,1.086161319,0.367942788,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,olanzapine,DB00334
,99950,DB00715,10012174,60,4783,33,2254,0.502639265,0.856852016,0.549494915,1.357098639,0.663781198,DB0071510012174_,0.409802704,-0.154490052,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,paroxetine,DB00715
,99955,DB00480,10013781,243,67185,133,67529,1.06467259074449e-08,1.83640294,1.479981549,2.286684483,2.3837239393287e-07,DB0048010013781_,15.24943171,0.607808734,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,99958,DB00480,10013786,410,67018,294,67368,9.47353566822535e-06,1.40183121,1.203400196,1.634586752,0.000103733,DB0048010013786_,9.173686981,0.337779389,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,99959,DB00588,10013786,87,16437,34,8434,0.210451728,1.312978416,0.873070489,2.015274935,0.361739712,DB0058810013786_,1.016830354,0.272298157,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,99960,DB00736,10013786,57,10534,26,5527,0.643329466,1.150242457,0.710590803,1.908245285,0.779707897,DB0073610013786_,0.248835921,0.139972753,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,esomeprazole,DB00736
,99966,DB01234,10028334,510,31115,440,32448,0.003996953,1.208741811,1.060887007,1.377623699,0.017069033,DB0123410028334_,4.070489399,0.189579993,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,99968,DB00588,10029331,143,16381,89,8379,0.163222535,0.821880663,0.625553254,1.084763397,0.301719775,DB0058810029331_,1.198256589,-0.196160073,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,99969,DB00736,10029331,107,10484,71,5482,0.1315764,0.788051529,0.577239688,1.081295214,0.2580093,DB0073610029331_,1.354759647,-0.2381918,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,99972,DB00399,10040844,41,6951,22,4976,0.306696183,1.334085936,0.775222382,2.354867419,0.473746609,DB0039910040844_,0.747082681,0.288246365,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,zoledronic acid,DB00399
,99973,DB00480,10040844,305,67123,256,67406,0.038069878,1.196426171,1.009598084,1.418745114,0.101745475,DB0048010040844_,2.285280927,0.179338922,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,99975,DB00999,10040844,88,21342,50,12189,1,1.005184033,0.701971843,1.45334147,1,DB0099910040844_,0,0.005170642,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,99986,DB00273,10013754,52,8429,13,2180,1,1.034530686,0.554250648,2.074971471,1,DB0027310013754_,0,0.03394788,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,99987,DB00331,10013754,61,24885,48,20704,0.84738111,1.057329454,0.712171181,1.577634804,0.923499077,DB0033110013754_,0.079585479,0.055746346,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,100018,DB01212,10012735,65,1954,32,1909,0.001378154,1.984129217,1.273737572,3.146883207,0.007171802,DB0121210012735_,4.937598287,0.685180136,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ceftriaxone,DB01212
,100022,DB00370,10010305,89,4452,76,3587,0.751846147,0.943554294,0.684562453,1.303091262,0.859977196,DB0037010010305_,0.150849406,-0.05810137,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,mirtazapine,DB00370
,100028,DB09053,10033557,21,2264,33,4019,0.671115801,1.129631148,0.61952302,2.017038173,0.800438343,DB0905310033557_,0.222595773,0.121891161,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,ibrutinib,DB09053
,100031,DB00425,10001497,98,12597,48,7436,0.303435232,1.205227413,0.843833535,1.741848136,0.469952277,DB0042510001497_,0.755124128,0.186668274,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,100032,DB00289,10019211,35,448,30,533,0.202305391,1.387570242,0.813235143,2.38022416,0.351692936,DB0028910019211_,1.044996824,0.32755419,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,atomoxetine,DB00289
,100033,DB08906,10019211,147,2046,45,1113,0.000743392,1.776748682,1.253430054,2.560413457,0.004302081,DB0890610019211_,5.448656424,0.574785111,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,fluticasone furoate,DB08906
,100035,DB00950,10037844,176,4542,54,2002,0.023462365,1.436541306,1.048224295,1.995886565,0.069951177,DB0095010037844_,2.659957745,0.362238354,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,fexofenadine,DB00950
,100037,DB00950,10047513,39,4679,19,2037,0.669328445,0.893633211,0.502697267,1.641426692,0.799241257,DB0095010047513_,0.22409243,-0.112459867,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,fexofenadine,DB00950
,100049,DB00203,10013950,67,13811,36,8902,0.418952178,1.19955312,0.787820321,1.853689431,0.588005019,DB0020310013950_,0.531019796,0.181949088,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,100051,DB01240,10020772,49,5702,13,1563,1,1.033206732,0.550270083,2.081523415,1,DB0124010020772_,0,0.032667298,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,epoprostenol,DB01240
,100056,DB00887,10037087,45,2296,32,1783,0.729443995,1.092053682,0.675667132,1.783466754,0.842369049,DB0088710037087_,0.17153706,0.088060035,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,bumetanide,DB00887
,100062,DB00175,10016322,151,7980,66,6040,0.000177096,1.731605562,1.285760297,2.35373645,0.001300636,DB0017510016322_,6.644902239,0.549049048,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,100063,DB00924,10016322,180,9982,58,4193,0.085398989,1.303563647,0.962340402,1.788227874,0.187371655,DB0092410016322_,1.674661176,0.265101781,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,100077,DB00363,10012378,41,4587,38,6850,0.037934534,1.611131535,1.009001666,2.578541974,0.10149211,DB0036310012378_,2.287774213,0.476936749,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,100079,DB00289,10013709,48,435,48,515,0.453227244,1.183712962,0.760146266,1.843381513,0.620796149,DB0028910013709_,0.476752513,0.168656077,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,atomoxetine,DB00289
,100080,DB00363,10013709,109,4519,88,6800,1.8560254432408e-05,1.863687694,1.390696226,2.503590159,0.000187061,DB0036310013709_,8.584073332,0.622557156,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,clozapine,DB00363
,100093,DB00331,10061284,42,24904,20,20732,0.040978898,1.748176039,1.003380772,3.144302179,0.107626933,DB0033110061284_,2.229084358,0.558572981,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,metformin,DB00331
,100104,DB00682,10020765,40,19419,36,16328,0.818012782,0.934270505,0.580231857,1.509164234,0.902853915,DB0068210020765_,0.102194516,-0.067989262,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,100107,DB00158,10022004,99,16716,23,8081,0.000926986,2.080793497,1.310268381,3.435942847,0.005175958,DB0015810022004_,5.263730915,0.73274931,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,100108,DB00497,10022004,84,19183,45,16330,0.01296043,1.589021369,1.092852306,2.33738502,0.043767573,DB0049710022004_,3.128862089,0.463118336,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,100109,DB00682,10022004,116,19343,44,16320,3.12038398051668e-06,2.224239517,1.558412105,3.225149855,3.91967947086648e-05,DB0068210022004_,10.14691558,0.799415067,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,100110,DB00814,10022004,56,8231,13,3402,0.06283238,1.780359278,0.960030178,3.553659034,0.148683734,DB0081410022004_,1.905933819,0.576815186,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,100111,DB01068,10022004,102,13661,31,6809,0.01601112,1.639946774,1.086406623,2.539871554,0.051854643,DB0106810022004_,2.959310805,0.494663787,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,100112,DB01175,10022004,82,10642,17,4875,0.002147844,2.209518836,1.297687182,3.979014059,0.010316163,DB0117510022004_,4.574043406,0.79277477,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,100117,DB01592,10018884,154,6122,81,2986,0.574530958,0.927334615,0.701411965,1.233634229,0.724293069,DB0159210018884_,0.322559178,-0.075440813,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,iron,DB01592
,100125,DB01592,10061428,138,6138,69,2998,0.881146817,0.976850639,0.723953638,1.328394792,0.950231562,DB0159210061428_,0.051049574,-0.023421515,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,iron,DB01592
,100128,DB00087,10016173,34,1335,18,729,1,1.031447045,0.561824027,1.954483021,1,DB0008710016173_,0,0.030962714,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,alemtuzumab,DB00087
,100134,DB00338,10009657,57,33617,38,22234,1,0.992086262,0.646496402,1.537887493,1,DB0033810009657_,0,-0.007945218,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,omeprazole,DB00338
,100149,DB00422,10013700,63,3372,23,2926,0.00027889,2.376449394,1.449221784,4.026010451,0.001902079,DB0042210013700_,6.264807943,0.865607523,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,methylphenidate,DB00422
,100160,DB00230,10024570,41,19633,12,8639,0.235138111,1.503419081,0.774725973,3.144020793,0.392145502,DB0023010024570_,0.93612233,0.407741901,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,100163,DB00635,10024570,61,32992,21,23773,0.00332558,2.093039972,1.256134807,3.620171076,0.014701121,DB0063510024570_,4.219831525,0.738617541,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,100178,DB00635,10048908,59,32994,24,23770,0.018926609,1.771043461,1.084584896,2.978140109,0.059161126,DB0063510048908_,2.827490614,0.571568899,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,prednisone,DB00635
,100248,DB00683,10013709,182,1402,173,1465,0.430839457,1.09926382,0.876201349,1.379507685,0.59929144,DB0068310013709_,0.512007256,0.094640701,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,midazolam,DB00683
,100278,DB04854,10012735,50,731,72,1414,0.141421141,1.343059108,0.906575874,1.976943859,0.271838437,DB0485410012735_,1.302547372,0.294949928,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,febuxostat,DB04854
,100282,DB00575,10029331,38,5206,45,3784,0.033282147,0.613834666,0.386986868,0.968990345,0.091875311,DB0057510029331_,2.387322935,-0.488029661,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,100287,DB00736,10038428,47,10544,20,5533,0.519572002,1.233117053,0.715775439,2.199450359,0.678751984,DB0073610038428_,0.387499485,0.209545153,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,esomeprazole,DB00736
,100288,DB01234,10038428,123,31502,148,32740,0.247384577,0.863744388,0.674091809,1.105157258,0.40660978,DB0123410038428_,0.899901324,-0.146478401,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,dexamethasone,DB01234
,100296,DB00736,10070863,86,10505,24,5529,0.004693967,1.885916007,1.186322408,3.105114212,0.019443845,DB0073610070863_,3.940224694,0.634413648,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,esomeprazole,DB00736
,100298,DB00196,10006451,66,5017,12,3273,6.23723026026597e-06,3.587643482,1.918897203,7.304439096,7.18272058668526e-05,DB0019610006451_,9.541247242,1.277495575,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,fluconazole,DB00196
,100300,DB00820,10017918,67,11848,17,5799,0.014053269,1.928944489,1.118577649,3.507709929,0.046734587,DB0082010017918_,3.063270772,0.656972956,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,tadalafil,DB00820
,100301,DB08932,10017918,96,19347,21,6576,0.070030698,1.553742706,0.960542985,2.626381566,0.161335456,DB0893210017918_,1.824269503,0.44066667,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,macitentan,DB08932
,100305,DB00193,10029366,38,19282,17,8685,1,1.006822506,0.554349632,1.903417809,1,DB0019310029366_,0,0.006799338,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,tramadol,DB00193
,100306,DB00316,10029366,173,65301,107,36846,0.455227676,0.912292464,0.712511728,1.172504168,0.622777833,DB0031610029366_,0.473565432,-0.091794656,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,100309,DB00019,10035528,61,18951,44,9485,0.077383833,0.693864738,0.462846602,1.047782833,0.17390852,DB0001910035528_,1.749225865,-0.36547824,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,pegfilgrastim,DB00019
,100310,DB00541,10035528,58,3076,105,4192,0.092159533,0.752818337,0.534742594,1.050989161,0.198680609,DB0054110035528_,1.616056722,-0.283931333,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,vincristine,DB00541
,100311,DB00997,10035528,83,5248,62,3452,0.493763873,0.880584256,0.624193254,1.247818435,0.656462072,DB0099710035528_,0.420890359,-0.127169664,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,doxorubicin,DB00997
,100312,DB01098,10035528,70,8079,51,7158,0.31488453,1.216062909,0.834376659,1.782922616,0.482454016,DB0109810035528_,0.728869667,0.195618516,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,rosuvastatin,DB01098
,100315,DB00476,10041349,306,16951,101,6076,0.496297867,1.085977153,0.862781481,1.376452728,0.658544986,DB0047610041349_,0.417722444,0.082480183,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,100319,DB00153,10003285,49,7374,15,3424,0.178398836,1.516771354,0.835126651,2.916453413,0.321840316,DB0015310003285_,1.133699769,0.416583966,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,100329,DB00169,10015946,68,38623,19,18156,0.04977922,1.68238678,0.999245822,2.964571491,0.124625849,DB0016910015946_,2.08243924,0.520213487,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,100335,DB06643,10020772,238,52183,41,7474,0.276543282,0.831418919,0.594328374,1.1893867,0.439995168,DB0664310020772_,0.820991534,-0.184621497,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,denosumab,DB06643
,100336,DB00153,10021097,104,7319,56,3383,0.391835013,0.858434691,0.612820131,1.213385862,0.56170163,DB0015310021097_,0.576784478,-0.152644675,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ergocalciferol,DB00153
,100337,DB06643,10021097,124,52297,31,7484,0.007363192,0.572430733,0.383258461,0.878886782,0.027877781,DB0664310021097_,3.579925278,-0.557863542,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,denosumab,DB06643
,100351,DB00177,10061428,80,4720,51,2799,0.71569974,0.930219069,0.644503727,1.353275886,0.831734356,DB0017710061428_,0.184242173,-0.072335162,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,valsartan,DB00177
,100354,DB00586,10012174,63,7046,30,2775,0.418181237,0.82710753,0.526130521,1.326658216,0.587189498,DB0058610012174_,0.532407686,-0.189820568,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,diclofenac,DB00586
,100375,DB00087,10008469,65,1304,8,739,2.36771020898203e-06,4.602149784,2.186374153,11.16746735,3.06728747378475e-05,DB0008710008469_,10.39213185,1.526523539,female,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,alemtuzumab,DB00087
,100376,DB00087,10011224,57,1312,20,727,0.089247013,1.578912604,0.925531433,2.797840877,0.194048949,DB0008710011224_,1.639644838,0.456736385,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alemtuzumab,DB00087
,100377,DB00087,10013968,98,1271,28,719,0.001429258,1.979359686,1.274638397,3.161847473,0.00738656,DB0008710013968_,4.908093097,0.682773401,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alemtuzumab,DB00087
,100378,DB00087,10019211,151,1218,26,721,2.30985357871691e-10,3.436214996,2.22948366,5.486756989,7.1219356383078e-09,DB0008710019211_,18.76008629,1.234370574,female,10019211,Headache,10029205,Nervous system disorders,Nerv,alemtuzumab,DB00087
,100379,DB00087,10037087,46,1323,8,739,0.001267754,3.210413106,1.489958871,7.9198957,0.006685308,DB0008710037087_,5.007843044,1.166399622,female,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,alemtuzumab,DB00087
,100380,DB00087,10046735,41,1328,10,737,0.017374174,2.274612979,1.112329643,5.123036,0.055345109,DB0008710046735_,2.894166994,0.821809919,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,alemtuzumab,DB00087
,100385,DB00482,10002034,73,8186,41,3030,0.043493698,0.659063692,0.442508928,0.99353356,0.112617036,DB0048210002034_,2.183762274,-0.416935099,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,celecoxib,DB00482
,100417,DB00230,10017944,66,19608,23,8628,0.35889803,1.262641999,0.774483909,2.128632408,0.528648417,DB0023010017944_,0.637431687,0.23320635,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,100419,DB01050,10028836,115,17993,33,9338,0.002233539,1.808529597,1.217687841,2.752799732,0.010645256,DB0105010028836_,4.542640963,0.592514138,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,100431,DB00537,10016288,64,7493,67,4231,0.00048431,0.539388151,0.376043097,0.77312731,0.003011971,DB0053710016288_,5.805160761,-0.617319835,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,ciprofloxacin,DB00537
,100432,DB01073,10016288,67,998,121,1529,0.314762651,0.848399183,0.613108073,1.16602757,0.482337566,DB0107310016288_,0.729111065,-0.164404019,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,fludarabine,DB01073
,100448,DB00230,10038428,46,19628,31,8620,0.081828252,0.651680103,0.404117903,1.063927239,0.18143025,DB0023010038428_,1.706883998,-0.428201477,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,pregabalin,DB00230
,100449,DB08895,10007559,66,28048,20,6626,0.336237079,0.779591324,0.466330739,1.35872807,0.505303117,DB0889510007559_,0.682596798,-0.24898544,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,tofacitinib,DB08895
,100456,DB00394,10003549,37,1602,17,777,1,1.055605073,0.575467081,2.012659275,1,DB0039410003549_,0,0.054114132,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,beclomethasone dipropionate,DB00394
,100457,DB00028,10013573,269,13189,78,5537,0.003567827,1.447853515,1.118958553,1.891373351,0.015565202,DB0002810013573_,4.162717498,0.370082125,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,100458,DB00668,10013573,210,9881,64,4239,0.016434524,1.407684988,1.056643501,1.897125784,0.05291945,DB0066810013573_,2.938984341,0.341946503,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,epinephrine,DB00668
,100464,DB00028,10028836,88,13370,10,5605,6.36482854577173e-06,3.689290153,1.912239941,7.965825831,7.31240213999672e-05,DB0002810028836_,9.523353635,1.305434069,female,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,human immunoglobulin g,DB00028
,100469,DB01075,10028836,105,19843,29,11068,0.000547325,2.019500487,1.326847559,3.163032887,0.003325193,DB0107510028836_,5.706227554,0.702850197,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,100470,DB00394,10037660,42,1597,27,767,0.243513048,0.747160835,0.446212423,1.270469224,0.401874593,DB0039410037660_,0.911615197,-0.291474809,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,beclomethasone dipropionate,DB00394
,100471,DB00028,10041349,72,13386,22,5593,0.213633691,1.367355304,0.837280188,2.318101304,0.365773943,DB0002810041349_,1.005739779,0.312878439,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,100472,DB00207,10041349,54,9026,20,5435,0.070583302,1.625751593,0.956184637,2.870649852,0.162323994,DB0020710041349_,1.818160976,0.485970227,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,100473,DB00281,10041349,113,11345,60,5611,0.684883181,0.931462544,0.674014183,1.298310789,0.809649617,DB0028110041349_,0.211153696,-0.0709993,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,100475,DB00668,10041349,60,10031,21,4282,0.467787001,1.219615693,0.73011131,2.113864782,0.634309955,DB0066810041349_,0.455217556,0.198535804,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,epinephrine,DB00668
,100478,DB00668,10042772,47,10044,20,4283,1,1.002095752,0.581496653,1.787595997,1,DB0066810042772_,0,0.002093559,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,epinephrine,DB00668
,100488,DB00758,10003239,182,8118,144,9930,0.0001033,1.545940925,1.233028179,1.941242588,0.000820441,DB0075810003239_,7.105668677,0.435632738,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,clopidogrel,DB00758
,100489,DB09053,10008531,18,2267,33,4019,1,0.967000365,0.511400639,1.772619248,1,DB0905310008531_,0,-0.033556407,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,ibrutinib,DB09053
,100490,DB00213,10047513,128,18767,53,13368,0.000827159,1.720273358,1.238663701,2.418362513,0.004707054,DB0021310047513_,5.358692974,0.542483207,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,pantoprazole,DB00213
,100493,DB00188,10019974,65,7821,70,8758,0.862704529,1.039832067,0.7292089,1.480887498,0.936336136,DB0018810019974_,0.065780747,0.039059226,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,bortezomib,DB00188
,100515,DB00437,10008469,39,6882,52,11494,0.328501883,1.252581882,0.804274807,1.936498164,0.497102591,DB0043710008469_,0.698958854,0.225206926,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,100516,DB00448,10008469,35,5110,19,3105,0.778881444,1.119327544,0.621709333,2.075214397,0.879514499,DB0044810008469_,0.128385229,0.112728098,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,100517,DB00741,10008469,31,4063,27,3147,0.691186235,0.889314715,0.512478141,1.552139799,0.813806812,DB0074110008469_,0.206032273,-0.117304096,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,100520,DB01377,10008469,36,3760,14,2656,0.06098157,1.816250585,0.953717164,3.652936614,0.145275801,DB0137710008469_,1.929121264,0.596774258,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,100523,DB00448,10021789,54,5091,34,3090,0.912089088,0.963961255,0.614686967,1.530809272,0.960588545,DB0044810021789_,0.040209114,-0.036704177,NA,10021789,Infection,10021881,Infections and infestations,Infec,lansoprazole,DB00448
,100524,DB00656,10021789,112,11901,35,6584,0.002421839,1.770288319,1.199952347,2.670547584,0.011371646,DB0065610021789_,4.476632197,0.571142426,NA,10021789,Infection,10021881,Infections and infestations,Infec,trazodone,DB00656
,100525,DB00741,10021789,44,4050,29,3145,0.553832162,1.178174924,0.71897291,1.957403561,0.707377652,DB0074110021789_,0.346190595,0.163966567,NA,10021789,Infection,10021881,Infections and infestations,Infec,hydrocortisone,DB00741
,100526,DB01377,10021789,27,3769,37,2633,0.010143133,0.509830236,0.297761637,0.862693936,0.035975205,DB0137710021789_,3.324925317,-0.67367748,NA,10021789,Infection,10021881,Infections and infestations,Infec,magnesium oxide,DB01377
,100527,DB14512,10021789,63,4781,30,2382,0.911968131,1.046259607,0.665137623,1.679260451,0.96056931,DB1451210021789_,0.040229139,0.045221526,NA,10021789,Infection,10021881,Infections and infestations,Infec,mometasone furoate,DB14512
,100528,DB00316,10034474,105,65369,66,36887,0.523875936,0.897735969,0.653447969,1.240998077,0.68195716,DB0031610034474_,0.382788438,-0.107879275,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,100530,DB00437,10034474,28,6893,33,11513,0.186089424,1.417106213,0.824263835,2.420943492,0.331572702,DB0043710034474_,1.10390818,0.348616914,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,allopurinol,DB00437
,100534,DB00904,10034474,86,22983,59,14397,0.608443752,0.913089592,0.647564105,1.295123847,0.751036372,DB0090410034474_,0.286301198,-0.090921273,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,ondansetron,DB00904
,100541,DB00437,10035598,75,6846,110,11436,0.401462328,1.138940317,0.836352693,1.543939263,0.571258216,DB0043710035598_,0.559913955,0.130098284,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,100542,DB00656,10035598,36,11977,30,6589,0.095103124,0.660152478,0.394924492,1.110846175,0.203359335,DB0065610035598_,1.592780739,-0.415284443,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,100549,DB00904,10001480,63,23006,41,14415,0.840835995,0.962760014,0.639186455,1.464358642,0.918695734,DB0090410001480_,0.084800295,-0.037951105,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,100552,DB00451,10007632,42,47229,10,15409,0.423830635,1.37027311,0.676362082,3.063850535,0.592605364,DB0045110007632_,0.523226592,0.31501007,NA,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,100553,DB00904,10007632,58,23011,36,14420,1,1.009613695,0.654521421,1.576413364,1,DB0090410007632_,0,0.009567778,NA,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,ondansetron,DB00904
,100566,DB00264,10058467,43,29564,44,24848,0.389468331,0.821385475,0.526600069,1.280419226,0.559377907,DB0026410058467_,0.580929992,-0.196762761,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metoprolol,DB00264
,100570,DB00480,10058467,45,67383,50,67612,0.68167939,0.903064389,0.589923754,1.378894402,0.807528608,DB0048010058467_,0.213776797,-0.101961423,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,100575,DB01234,10058467,33,31592,24,32864,0.187534162,1.430346485,0.819929042,2.529938581,0.333480056,DB0123410058467_,1.098172218,0.357916712,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,100581,DB00465,10025482,46,2058,14,869,0.319681051,1.387317495,0.744637748,2.747268309,0.487866278,DB0046510025482_,0.71771393,0.327372023,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ketorolac,DB00465
,100583,DB00343,10013952,42,8694,12,5083,0.032896611,2.046199414,1.056396399,4.273752889,0.091058069,DB0034310013952_,2.396257855,0.715984128,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,100591,DB01060,10067482,39,8548,21,5060,0.789851578,1.099344214,0.630194531,1.969343183,0.886130966,DB0106010067482_,0.120890522,0.094713833,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,100595,DB00005,10016454,102,127980,21,42398,0.047180535,1.609046952,0.998686965,2.71095939,0.119785606,DB0000510016454_,2.122051755,0.475642049,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,100606,DB05259,10022004,164,11106,29,2699,0.120348693,1.374294949,0.919453873,2.121239971,0.241819775,DB0525910022004_,1.41956256,0.317940835,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,100608,DB08910,10068319,52,16692,38,17450,0.112787442,1.430539552,0.923037848,2.235358813,0.230252644,DB0891010068319_,1.46857812,0.358051682,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,100609,DB00051,10035528,40,25691,25,11395,0.180150488,0.709662977,0.419875444,1.22119067,0.323999697,DB0005110035528_,1.1270127,-0.342965102,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,adalimumab,DB00051
,100611,DB00285,10050584,63,10888,8,3710,0.005688839,2.683355223,1.280178249,6.490632357,0.022685448,DB0028510050584_,3.786031598,0.987067961,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,100612,DB00727,10050584,57,3786,27,4146,0.000255146,2.311627795,1.434804444,3.810142863,0.001766264,DB0072710050584_,6.338888977,0.83795195,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,nitroglycerin,DB00727
,100616,DB00264,10074902,34,29573,22,24870,0.351138758,1.299672746,0.738186688,2.333112149,0.520874064,DB0026410074902_,0.652246986,0.262112499,NA,10074902,Expired product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,100626,DB01238,10061422,56,5194,69,3433,0.000622441,0.536482965,0.369181505,0.776622386,0.003714582,DB0123810061422_,5.595489253,-0.62272047,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,100629,DB00555,10008479,57,6990,32,3454,0.572669455,0.880193855,0.560020485,1.405485772,0.722727962,DB0055510008479_,0.32472239,-0.127613106,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,100630,DB00555,10020642,62,6985,32,3454,0.826622813,0.958082088,0.614368794,1.520298994,0.908584167,DB0055510020642_,0.095867751,-0.042821818,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,lamotrigine,DB00555
,100631,DB00654,10013774,44,3772,13,2585,0.00633763,2.319235052,1.223886521,4.702860187,0.024745187,DB0065410013774_,3.699124291,0.841237412,NA,10013774,Dry eye,10015919,Eye disorders,Eye,latanoprost,DB00654
,100636,DB00996,10022998,136,38817,93,22332,0.215828159,0.841330833,0.641211252,1.107929918,0.368379426,DB0099610022998_,0.998641824,-0.172770316,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,100655,DB00476,10016825,92,17165,28,6149,0.533042617,1.177025375,0.762883782,1.868745229,0.689790527,DB0047610016825_,0.371367312,0.162990387,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,duloxetine,DB00476
,100656,DB00999,10016825,103,21327,35,12204,0.007581921,1.683973147,1.136712385,2.548700367,0.028535336,DB0099910016825_,3.556612096,0.52115597,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,hydrochlorothiazide,DB00999
,100658,DB00281,10022086,117,11341,54,5617,0.743999462,1.073106536,0.769615163,1.512803727,0.853713896,DB0028110022086_,0.158159158,0.070557747,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,100664,DB00722,10040882,53,25350,49,25983,0.621331248,1.108638814,0.737151594,1.670211713,0.761615028,DB0072210040882_,0.272314064,0.103132969,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,100666,DB00476,10062519,40,17217,14,6163,1,1.022751641,0.544283695,2.036668724,1,DB0047610062519_,0,0.022496682,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,100672,DB01115,10028596,31,3569,24,2244,0.487364763,0.812170077,0.460027103,1.450196715,0.6511988,DB0111510028596_,0.428940306,-0.208045506,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,nifedipine,DB01115
,100690,DB01257,10053762,79,857,38,530,0.234526579,1.285487364,0.848257412,1.976564354,0.391411228,DB0125710053762_,0.937996539,0.251137918,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,eculizumab,DB01257
,100692,DB01611,10006451,144,11769,12,2349,0.001585334,2.39501302,1.326797016,4.751016301,0.008036743,DB0161110006451_,4.823731404,0.873388667,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,hydroxychloroquine,DB01611
,100694,DB01611,10012174,75,11838,11,2350,0.465521532,1.353471303,0.713421435,2.831469922,0.632314471,DB0161110012174_,0.458368428,0.302672628,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,hydroxychloroquine,DB01611
,100703,DB01267,10020737,40,2812,16,3699,3.13261276498923e-05,3.288008163,1.796266732,6.302847917,0.0002946,DB0126710020737_,8.129891732,1.19028196,female,10020737,Hyperprolactinaemia,10014698,Endocrine disorders,Endo,paliperidone,DB01267
,100707,DB00331,10001053,53,24893,73,20679,0.005335595,0.603136895,0.41504877,0.871376147,0.02154318,DB0033110001053_,3.837695974,-0.505611084,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,100708,DB00437,10001053,51,6870,57,11489,0.045613473,1.496218053,1.003777491,2.22515373,0.116748637,DB0043710001053_,2.147732058,0.402940627,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,100711,DB00542,10021097,34,1652,31,1393,0.801875415,0.92485064,0.548410602,1.564736904,0.892815853,DB0054210021097_,0.113374931,-0.078123025,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,benazepril,DB00542
,100729,DB01224,10024855,74,8034,65,5852,0.300388901,0.82927563,0.585149152,1.177687128,0.466567528,DB0122410024855_,0.762352515,-0.187202694,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,100730,DB01238,10024855,44,5206,25,3477,0.540420577,1.175419912,0.702273913,2.008192503,0.695972984,DB0123810024855_,0.362444435,0.161625456,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,100731,DB00555,10035664,95,6952,56,3430,0.296770634,0.837016548,0.593774258,1.189438385,0.4626014,DB0055510035664_,0.770889503,-0.177911438,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,lamotrigine,DB00555
,100732,DB01224,10035664,141,7967,130,5787,0.054225274,0.787853781,0.614820071,1.010230845,0.132889965,DB0122410035664_,2.018233824,-0.238442764,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,quetiapine,DB01224
,100733,DB01238,10035664,81,5169,42,3460,0.195033873,1.290900559,0.876320754,1.926240714,0.343033581,DB0123810035664_,1.069926933,0.255340083,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,aripiprazole,DB01238
,100734,DB00051,10052428,49,25682,18,11402,0.596188971,1.208559531,0.691242296,2.205416486,0.741603667,DB0005110052428_,0.298940319,0.18942918,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,100739,DB14726,10018964,18,1999,37,2811,0.216004465,0.684150732,0.365543267,1.236676149,0.368620507,DB1472610018964_,0.997987602,-0.379577018,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dabigatran,DB14726
,100762,DB00395,10003988,58,2126,13,723,0.21279468,1.517007242,0.815614933,3.036419627,0.364777002,DB0039510003988_,1.008469064,0.416739474,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,carisoprodol,DB00395
,100763,DB06724,10003988,244,7685,71,3848,4.41791476489906e-05,1.720697537,1.311983879,2.280727251,0.000397756,DB0672410003988_,7.829671587,0.542729754,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,100784,DB00395,10033425,53,2131,17,719,1,1.051855176,0.594902669,1.950948626,1,DB0039510033425_,0,0.05055544,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,carisoprodol,DB00395
,100785,DB01225,10033425,95,4949,67,4573,0.096156925,1.310145643,0.945682435,1.823738908,0.204978288,DB0122510033425_,1.584851217,0.270138309,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,enoxaparin,DB01225
,100809,DB00115,10020100,96,18329,42,10430,0.182772959,1.300668033,0.895376987,1.917984612,0.327405679,DB0011510020100_,1.116555269,0.262878004,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,100810,DB00682,10020100,108,19351,56,16308,0.002806393,1.625272284,1.165514847,2.288026953,0.012797719,DB0068210020100_,4.358488341,0.485675361,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,100816,DB09035,10029354,33,4693,28,6662,0.050251525,1.672935167,0.97883549,2.877907428,0.125461753,DB0903510029354_,2.075754322,0.514579668,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,nivolumab,DB09035
,100817,DB00364,10037660,72,2678,33,1367,0.676270279,1.113686961,0.723764418,1.745711241,0.803842191,DB0036410037660_,0.218352309,0.107676097,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sucralfate,DB00364
,100832,DB00480,10048685,34,67394,18,67644,0.026728787,1.895875535,1.04098873,3.566153784,0.077413493,DB0048010048685_,2.558594189,0.639680755,NA,10048685,Oral infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,100846,DB00480,10061257,22,67406,39,67623,0.039590643,0.565924366,0.319540175,0.978489659,0.10483982,DB0048010061257_,2.255321615,-0.569294839,NA,10061257,Jaw disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,100861,DB00722,10021114,65,25338,26,26006,2.20366318722651e-05,2.565956291,1.60476623,4.215261472,0.000217022,DB0072210021114_,8.43550984,0.942331232,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,lisinopril,DB00722
,100863,DB01039,10047899,69,2904,36,3015,0.0007596,1.989692922,1.306606124,3.075917274,0.004379971,DB0103910047899_,5.430713128,0.687980316,NA,10047899,Weight increased,10022891,Investigations,Inv,fenofibrate,DB01039
,100865,DB00722,10067585,66,25337,42,25990,0.015867593,1.611902841,1.078034502,2.434055437,0.051512688,DB0072210067585_,2.965927131,0.47741537,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,100868,DB00490,10013573,123,3947,60,1516,0.154036145,0.787398258,0.57026377,1.097263697,0.289595885,DB0049010013573_,1.239268826,-0.239021113,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,buspirone,DB00490
,100869,DB00490,10040108,48,4022,35,1541,0.006229173,0.525491344,0.331464978,0.840594982,0.02438796,DB0049010040108_,3.713665694,-0.643421561,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,buspirone,DB00490
,100877,DB00515,10043071,40,1830,49,2102,0.830057999,0.937656458,0.598710293,1.460904467,0.910813187,DB0051510043071_,0.093417466,-0.064371646,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,cisplatin,DB00515
,100895,DB00281,10015150,112,11346,29,5642,0.001165396,1.920417393,1.265221927,3.00126138,0.006252154,DB0028110015150_,5.074829266,0.652542555,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,lidocaine,DB00281
,100898,DB06228,10067383,42,15870,34,16042,0.359470333,1.248670943,0.775094754,2.02480002,0.529189454,DB0622810067383_,0.636408775,0.22207974,NA,10067383,Abdominal wall haematoma,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,100904,DB06643,10037867,66,52355,9,7506,1,1.05136491,0.521273419,2.40112874,1,DB0664310037867_,0,0.050089234,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,100905,DB06643,10037884,215,52206,35,7480,0.502266723,0.880159812,0.613059947,1.297924822,0.663554525,DB0664310037884_,0.410144251,-0.127651783,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,100937,DB00582,10016256,29,1101,31,1543,0.354234842,1.310888275,0.757398791,2.262978086,0.524087103,DB0058210016256_,0.646097381,0.27070498,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,voriconazole,DB00582
,100976,DB01050,10012373,73,18035,16,9355,0.001048774,2.366566515,1.363363416,4.359125625,0.005734769,DB0105010012373_,5.161207821,0.861440177,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,100978,DB08908,10049438,41,10632,18,3261,0.217998558,0.698649851,0.391867877,1.293844155,0.371203575,DB0890810049438_,0.991004648,-0.358605591,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,100979,DB01238,10025482,104,5146,40,3462,0.002574555,1.749055954,1.200360233,2.592656857,0.011939339,DB0123810025482_,4.427916536,0.559076188,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,100998,DB00843,10022437,50,2144,40,2133,0.338309235,1.243522313,0.800333149,1.94312537,0.507401115,DB0084310022437_,0.678453434,0.217947928,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,donepezil,DB00843
,101010,DB00451,10026749,44,47227,23,15396,0.086975889,0.623657664,0.36836623,1.082387208,0.190006752,DB0045110026749_,1.660695673,-0.472153676,NA,10026749,Mania,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,101021,DB00635,10001367,45,33008,68,23726,0.000114491,0.475674083,0.318825552,0.703716314,0.000895716,DB0063510001367_,7.017886776,-0.743022359,NA,10001367,Adrenal insufficiency,10014698,Endocrine disorders,Endo,prednisone,DB00635
,101030,DB00059,10009887,35,792,54,1053,0.513175979,0.861815947,0.540893335,1.357825336,0.673229717,DB0005910009887_,0.395668675,-0.148713549,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,pegaspargase,DB00059
,101031,DB00541,10009887,59,3075,114,4183,0.029377327,0.70406096,0.50338862,0.976019463,0.083326109,DB0054110009887_,2.484993344,-0.350890335,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,vincristine,DB00541
,101032,DB00694,10009887,28,606,47,724,0.189661824,0.711918214,0.423749233,1.176730421,0.336081238,DB0069410009887_,1.090402369,-0.339792242,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,daunorubicin,DB00694
,101037,DB00059,10020635,27,800,35,1072,0.897005779,1.033713009,0.596431431,1.774013103,0.956338178,DB0005910020635_,0.044643686,0.033157184,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,pegaspargase,DB00059
,101038,DB00541,10020635,38,3096,58,4239,0.677620202,0.897038613,0.578104558,1.377699233,0.804591725,DB0054110020635_,0.217420304,-0.108656371,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,vincristine,DB00541
,101051,DB00338,10073508,37,33637,13,22259,0.059131559,1.883393242,0.978200722,3.862349993,0.141865007,DB0033810073508_,1.952879327,0.633075066,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,101059,DB00175,10064355,41,8090,28,6078,0.7166173,1.10013581,0.663217612,1.849349318,0.832470586,DB0017510064355_,0.183357389,0.095433636,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,101063,DB11093,10011906,31,1626,33,627,0.000104735,0.362422042,0.212671602,0.616194877,0.000830328,DB1109310011906_,7.093689478,-1.014945884,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,calcium citrate,DB11093
,101068,DB00555,10054112,30,7017,23,3463,0.14225146,0.643730076,0.360942411,1.162357221,0.272935481,DB0055510054112_,1.298519846,-0.440475777,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,lamotrigine,DB00555
,101069,DB01156,10054112,79,13543,46,6282,0.247045567,0.796656162,0.546256849,1.173648837,0.406179566,DB0115610054112_,0.900959935,-0.227332108,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,bupropion,DB01156
,101070,DB11065,10011906,102,3084,89,2599,0.825027075,0.965825757,0.716036998,1.304759124,0.90739515,DB1106510011906_,0.097177257,-0.034771836,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pancrelipase amylase,DB11065
,101082,DB00028,10048634,365,13093,80,5535,2.6937181245301e-08,1.928716356,1.507125373,2.493917689,5.48658511455046e-07,DB0002810048634_,14.41578961,0.656854681,NA,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,101083,DB00316,10048634,137,65337,20,36933,5.93147187320114e-11,3.8720498,2.411426249,6.54019096,2.00913322406046e-09,DB0031610048634_,20.02556244,1.353784031,female,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,101084,DB01075,10048634,135,19813,30,11067,8.0858943918229e-07,2.513509984,1.680894116,3.871878313,1.18802534426532e-05,DB0107510048634_,11.34063291,0.921680176,NA,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,101085,DB00028,10064774,212,13246,90,5525,0.898769911,0.982519373,0.762651736,1.274349313,0.95647837,DB0002810064774_,0.044497104,-0.017635217,NA,10064774,Infusion site extravasation,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,101092,DB00343,10055798,61,8675,53,5042,0.040108321,0.668987557,0.454555053,0.987244226,0.10589596,DB0034310055798_,2.245298177,-0.401989818,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,diltiazem,DB00343
,101093,DB01118,10055798,27,3036,55,4654,0.256462161,0.752560171,0.455327619,1.216736082,0.417289789,DB0111810055798_,0.873974362,-0.284274324,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,amiodarone,DB01118
,101095,DB06403,10012378,100,21371,29,6632,0.835651166,1.070082216,0.700943871,1.680300267,0.914888097,DB0640310012378_,0.088953519,0.067735483,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ambrisentan,DB06403
,101097,DB00230,10033318,38,19636,18,8633,0.773148813,0.928158035,0.516526165,1.7287894,0.87595761,DB0023010033318_,0.132437579,-0.074553264,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,pregabalin,DB00230
,101098,DB00455,10033318,54,9347,21,5097,0.22544576,1.40219125,0.831885046,2.447111829,0.380232743,DB0045510033318_,0.966971732,0.338036191,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,loratadine,DB00455
,101099,DB00476,10033318,52,17205,13,6164,0.323000705,1.433013353,0.768829838,2.87093124,0.491423236,DB0047610033318_,0.710449534,0.359779467,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,duloxetine,DB00476
,101100,DB08931,10033318,353,6224,121,2325,0.45746595,1.089778158,0.878906724,1.358589879,0.624823003,DB0893110033318_,0.470286865,0.085974151,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,riociguat,DB08931
,101102,DB00455,10042458,76,9325,33,5085,0.31444584,1.255882851,0.823039965,1.954307452,0.482034754,DB0045510042458_,0.729739063,0.227838792,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,loratadine,DB00455
,101104,DB00341,10002424,40,11365,18,5050,1,0.987437647,0.552586214,1.831747052,1,DB0034110002424_,0,-0.012641926,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,cetirizine,DB00341
,101108,DB00043,10015150,80,6333,27,2273,0.826286704,1.063440071,0.677847877,1.716310802,0.908324454,DB0004310015150_,0.096153636,0.061509004,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,omalizumab,DB00043
,101110,DB00043,10016825,78,6335,19,2281,0.133356669,1.478041426,0.883993811,2.591299952,0.260463796,DB0004310016825_,1.345291407,0.390717851,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,omalizumab,DB00043
,101113,DB00043,10043528,87,6326,14,2286,0.00301345,2.245514574,1.26588316,4.285757349,0.013563103,DB0004310043528_,4.30040218,0.808934704,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omalizumab,DB00043
,101117,DB00695,10009887,73,27976,34,20494,0.030834945,1.572824645,1.033003838,2.438413149,0.086559143,DB0069510009887_,2.446927365,0.45287314,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,101118,DB00787,10009887,64,16936,46,17202,0.085204455,1.413135611,0.951852209,2.112474556,0.187082947,DB0078710009887_,1.676203194,0.345811073,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,101119,DB01225,10009887,38,5006,18,4622,0.021854666,1.949035881,1.083631934,3.633312299,0.066287781,DB0122510009887_,2.7137497,0.66733483,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,101120,DB06724,10009887,35,7894,19,3900,0.772396886,0.91009508,0.505773426,1.686457647,0.875407561,DB0672410009887_,0.133065717,-0.094206201,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,101121,DB01225,10016288,56,4988,73,4567,0.050920991,0.702406452,0.485639668,1.011237629,0.126735938,DB0122510016288_,2.065649588,-0.353243051,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,enoxaparin,DB01225
,101122,DB00476,10066901,38,17219,14,6163,0.8761298,0.971493205,0.514118646,1.942504746,0.946938539,DB0047610066901_,0.054521089,-0.028921004,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,101126,DB00370,10000081,75,4466,41,3622,0.047937062,1.483494638,0.997952681,2.232971662,0.121232085,DB0037010000081_,2.110048516,0.394400546,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,mirtazapine,DB00370
,101137,DB00635,10021328,26,33027,38,23756,0.005129152,0.492145412,0.286849982,0.832249083,0.02087801,DB0063510021328_,3.869058837,-0.708981054,NA,10021328,Ileus,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,101150,DB00996,10002198,83,38870,26,22399,0.005243439,1.83956227,1.171358639,2.979141569,0.021254304,DB0099610002198_,3.851195874,0.609527647,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,gabapentin,DB00996
,101158,DB01156,10043414,35,13587,22,6306,0.257890006,0.738363276,0.420772025,1.322468197,0.41878348,DB0115610043414_,0.870401246,-0.303319332,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,101159,DB09072,10043414,50,6421,26,2509,0.249438223,0.751461008,0.457788254,1.260603868,0.408860295,DB0907210043414_,0.894381759,-0.285735957,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,101160,DB09072,10046571,48,6423,6,2529,0.003656516,3.149899975,1.343629208,9.017025206,0.015871772,DB0907210046571_,4.143213064,1.147370698,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,sodium oxybate,DB09072
,101164,DB06723,10019211,54,976,18,592,0.03341257,1.819060512,1.038306266,3.328978158,0.092170793,DB0672310019211_,2.38411198,0.598320166,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,aluminum hydroxide,DB06723
,101173,DB00563,10020144,50,46596,26,15322,0.06249699,0.632364187,0.386046529,1.0586963,0.148094061,DB0056310020144_,1.90990766,-0.458289806,NA,10020144,Histoplasmosis disseminated,10021881,Infections and infestations,Infec,methotrexate,DB00563
,101174,DB00635,10020144,61,32992,44,23750,1,0.998003617,0.666011707,1.506317721,1,DB0063510020144_,0,-0.001998378,NA,10020144,Histoplasmosis disseminated,10021881,Infections and infestations,Infec,prednisone,DB00635
,101197,DB00136,10040047,20,2072,32,1650,0.016323569,0.497806791,0.268760602,0.901270924,0.052649245,DB0013610040047_,2.944103382,-0.697543247,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,calcitriol,DB00136
,101198,DB00222,10040047,34,3172,42,3086,0.355951818,0.78760761,0.484566266,1.271874084,0.525628851,DB0022210040047_,0.643159922,-0.23875527,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,glimepiride,DB00222
,101199,DB00678,10040047,130,15469,114,10610,0.057839561,0.782168851,0.602756655,1.016107656,0.139396845,DB0067810040047_,1.970430416,-0.24568464,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,losartan,DB00678
,101200,DB01281,10040047,55,8877,19,1779,0.058706708,0.580157337,0.33799497,1.037839894,0.141077511,DB0128110040047_,1.958445815,-0.544455942,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,abatacept,DB01281
,101201,DB01611,10040047,85,11828,13,2348,0.49424599,1.29793978,0.718348395,2.541621575,0.656804057,DB0161110040047_,0.420369543,0.260778223,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,hydroxychloroquine,DB01611
,101203,DB08877,10003988,46,3243,38,3191,0.443887901,1.191082774,0.755909942,1.886669336,0.611877887,DB0887710003988_,0.491222548,0.174862788,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ruxolitinib,DB08877
,101206,DB09033,10012735,112,2512,54,1615,0.088766187,1.333364177,0.949125314,1.892508707,0.193203264,DB0903310012735_,1.644012464,0.287705205,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,vedolizumab,DB09033
,101208,DB09033,10037660,80,2544,52,1617,0.927834475,0.977861602,0.677087838,1.422704073,0.969784046,DB0903310037660_,0.030681865,-0.02238713,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,vedolizumab,DB09033
,101210,DB08877,10022437,28,3261,44,3185,0.057395704,0.621581637,0.37163627,1.023812231,0.138528634,DB0887710022437_,1.976678231,-0.475488021,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ruxolitinib,DB08877
,101227,DB00231,10007559,31,3265,22,2117,0.778337172,0.91365976,0.510670207,1.660973797,0.87912651,DB0023110007559_,0.128826467,-0.090297031,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,temazepam,DB00231
,101262,DB00575,10011906,236,5008,157,3672,0.374870748,1.102194727,0.892661377,1.363707016,0.544694089,DB0057510011906_,0.607530947,0.097303399,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,101263,DB01016,10011906,29,1072,63,1165,0.001949903,0.500396049,0.308211413,0.795518444,0.009539027,DB0101610011906_,4.652363841,-0.692355396,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,glyburide,DB01016
,101293,DB00331,10024855,131,24815,117,20635,0.609072813,0.931069395,0.719537277,1.205960504,0.751618727,DB0033110024855_,0.285526095,-0.071421467,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,metformin,DB00331
,101299,DB00028,10017533,57,13401,10,5605,0.007148307,2.383950358,1.205493391,5.240365271,0.027238801,DB0002810017533_,3.603112799,0.868758926,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,101301,DB00471,10017533,63,14126,6,5459,0.000131395,4.057731194,1.762316068,11.48020264,0.001006766,DB0047110017533_,6.901012006,1.400623998,female,10017533,Fungal infection,10021881,Infections and infestations,Infec,montelukast,DB00471
,101304,DB00668,10017533,55,10036,6,4297,0.000351265,3.924851562,1.690656452,11.16395969,0.002300197,DB0066810017533_,6.07476045,1.367328532,female,10017533,Fungal infection,10021881,Infections and infestations,Infec,epinephrine,DB00668
,101317,DB00028,10047461,83,13375,29,5586,0.466998642,1.195306752,0.773728011,1.895071772,0.633535099,DB0002810047461_,0.456439876,0.178402848,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,101320,DB00451,10047461,117,47154,27,15392,0.120586308,1.414454769,0.924008039,2.237683153,0.242213902,DB0045110047461_,1.417934052,0.346744134,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,101321,DB00471,10047461,58,14131,14,5451,0.146134365,1.598120685,0.87945882,3.105169201,0.278606063,DB0047110047461_,1.277956457,0.468828367,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,montelukast,DB00471
,101324,DB00668,10047461,57,10034,26,4277,0.810080379,0.934478955,0.577144703,1.550603454,0.897774334,DB0066810047461_,0.107836541,-0.067766172,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,epinephrine,DB00668
,101327,DB09153,10047461,40,7759,31,5668,0.810668006,0.942607833,0.57423992,1.56043831,0.898198349,DB0915310047461_,0.107364356,-0.059104955,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,101330,DB00316,10019641,50,65424,40,36913,0.10057569,0.705293816,0.455963088,1.09720654,0.211719217,DB0031610019641_,1.552494331,-0.349140803,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,101349,DB00264,10022972,39,29568,33,24859,1,0.993601445,0.608713357,1.63078495,1,DB0026410022972_,0,-0.006419114,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,metoprolol,DB00264
,101350,DB00338,10022972,60,33614,53,22219,0.124861846,0.748323254,0.508277226,1.104443817,0.248379602,DB0033810022972_,1.39279705,-0.289920237,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,omeprazole,DB00338
,101369,DB00316,10023003,102,65372,23,36930,2.20289822294513e-05,2.505277231,1.58119715,4.129514083,0.000216988,DB0031610023003_,8.43566968,0.9183994,NA,10023003,Irritable bowel syndrome,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,101370,DB00338,10023003,61,33613,15,22257,0.000239322,2.692690666,1.511539887,5.102113297,0.001673471,DB0033810023003_,6.392855342,0.990540941,NA,10023003,Irritable bowel syndrome,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,101378,DB00999,10023003,52,21378,13,12226,0.006272918,2.287532999,1.227651663,4.581208415,0.0245411,DB0099910023003_,3.707406001,0.827473944,NA,10023003,Irritable bowel syndrome,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,101403,DB00863,10033661,26,10647,36,5804,0.000278136,0.393726783,0.228031047,0.671198232,0.001898414,DB0086310033661_,6.266736548,-0.932098053,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,ranitidine,DB00863
,101411,DB13961,10033661,30,9427,36,6378,0.023161198,0.563843311,0.335019525,0.942580762,0.069275387,DB1396110033661_,2.669665604,-0.572978883,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,fish oil,DB13961
,101414,DB00338,10041660,26,33648,37,22235,0.002818013,0.464354966,0.269912219,0.788038208,0.012841793,DB0033810041660_,4.355050348,-0.767106007,NA,10041660,Splenomegaly,10005329,Blood and lymphatic system disorders,Blood,omeprazole,DB00338
,101431,DB00455,10043554,44,9357,35,5083,0.098579527,0.682907205,0.427545229,1.098295218,0.208748569,DB0045510043554_,1.56662477,-0.381396293,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,loratadine,DB00455
,101433,DB00727,10043554,28,3815,35,4138,0.614067691,0.867748412,0.507440202,1.471347091,0.755669793,DB0072710043554_,0.28015078,-0.141853454,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,nitroglycerin,DB00727
,101448,DB00374,10015958,48,17668,14,5710,0.882345375,1.108050968,0.600347511,2.177764109,0.950859822,DB0037410015958_,0.050388628,0.102602587,NA,10015958,Eye pain,10015919,Eye disorders,Eye,treprostinil,DB00374
,101449,DB06228,10021143,64,15848,31,16045,0.000630854,2.090121265,1.340232749,3.322910109,0.00375626,DB0622810021143_,5.584331616,0.737222086,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,101450,DB09054,10011906,80,344,122,459,0.426118567,0.875068403,0.629582498,1.211807964,0.594791024,DB0905410011906_,0.519545155,-0.13345322,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,idelalisib,DB09054
,101453,DB01257,10013709,47,889,21,547,0.251276493,1.376813847,0.796921653,2.452661972,0.411221146,DB0125710013709_,0.888624141,0.319772023,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,eculizumab,DB01257
,101466,DB00169,10011878,71,38620,32,18143,0.915939433,1.042319187,0.67732186,1.636123845,0.962395043,DB0016910011878_,0.038330265,0.041448218,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,cholecalciferol,DB00169
,101468,DB00331,10011878,26,24920,34,20718,0.091497704,0.635775741,0.366242271,1.091701526,0.197667227,DB0033110011878_,1.621170332,-0.452909386,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,metformin,DB00331
,101469,DB00338,10011878,58,33616,35,22237,0.750660823,1.09621691,0.708234983,1.719051215,0.859058816,DB0033810011878_,0.151917889,0.091865079,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,omeprazole,DB00338
,101475,DB00338,10013786,196,33478,104,22168,0.075886202,1.247910801,0.978257799,1.599562344,0.17130775,DB0033810013786_,1.764293633,0.221470794,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,101477,DB00924,10013786,51,10111,22,4229,0.898010953,0.969597595,0.576705253,1.681172487,0.956338178,DB0092410013786_,0.044643686,-0.030874144,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,cyclobenzaprine,DB00924
,101478,DB00115,10013946,149,18276,52,10420,0.00193537,1.63366292,1.182754356,2.28770723,0.009479402,DB0011510013946_,4.658634046,0.490824684,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,101480,DB00678,10013946,110,15489,60,10664,0.158862748,1.262217685,0.912422315,1.760779382,0.295994178,DB0067810013946_,1.217415493,0.232870241,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,101481,DB00924,10013946,78,10084,17,4234,0.012641354,1.926401064,1.127876965,3.477852599,0.042918883,DB0092410013946_,3.14844338,0.655653528,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,101482,DB00115,10020642,151,18274,74,10398,0.329703064,1.161099244,0.872515233,1.556586383,0.498369731,DB0011510020642_,0.696413045,0.14936718,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,101483,DB00177,10020642,32,4768,25,2825,0.336068561,0.758434244,0.434458215,1.337871357,0.505193568,DB0017710020642_,0.68281362,-0.276499176,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,valsartan,DB00177
,101484,DB00624,10020642,7,555,51,4345,0.834406547,1.074553592,0.409356867,2.393767357,0.914096571,DB0062410020642_,0.089819056,0.071905312,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,testosterone,DB00624
,101485,DB00678,10020642,125,15474,74,10650,0.311872523,1.16254718,0.864248825,1.573261139,0.479305927,DB0067810020642_,0.735416206,0.150613443,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,101486,DB01136,10020642,51,9833,63,11052,0.639075947,0.909908858,0.615743514,1.338878947,0.776154316,DB0113610020642_,0.253403918,-0.094410841,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,carvedilol,DB01136
,101487,DB00115,10028372,191,18234,127,10345,0.177293746,0.853265113,0.677270878,1.07798312,0.320363395,DB0011510028372_,1.138299318,-0.158684979,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,101488,DB00177,10028372,40,4760,25,2825,0.897621182,0.949592114,0.560749015,1.636956393,0.956338178,DB0017710028372_,0.044643686,-0.051722741,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,valsartan,DB00177
,101489,DB00115,10031282,51,18374,12,10460,0.003724633,2.419384215,1.271811916,4.987456863,0.016098325,DB0011510031282_,4.129040029,0.883513051,NA,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,101492,DB00338,10031282,90,33584,14,22258,4.81259431597678e-09,4.260474379,2.411350268,8.107186498,1.15995156280444e-07,DB0033810031282_,15.9697174,1.449380511,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,101493,DB00451,10031282,121,47150,11,15408,2.27226895109794e-06,3.594705494,1.938492736,7.39530649,2.96438317402768e-05,DB0045110031282_,10.42625649,1.279462067,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,101495,DB00678,10031282,43,15556,8,10716,0.000160031,3.702480972,1.719838466,9.121317812,0.001192527,DB0067810031282_,6.731680542,1.309003128,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,101496,DB00115,10046543,52,18373,28,10444,0.907409384,1.055681753,0.654095101,1.737172535,0.958745315,DB0011510046543_,0.042129813,0.054186769,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,cyanocobalamin,DB00115
,101497,DB00331,10046543,50,24896,40,20712,0.915746904,1.039932172,0.672161397,1.618241191,0.96231589,DB0033110046543_,0.038412514,0.039155492,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,101522,DB01240,10012378,51,5700,13,1563,1,1.07572253,0.574884775,2.161864254,1,DB0124010012378_,0,0.072992556,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,epoprostenol,DB01240
,101523,DB00695,10060800,120,27929,53,20475,0.001967551,1.659847911,1.191187478,2.339940706,0.009606589,DB0069510060800_,4.645306092,0.506725978,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,furosemide,DB00695
,101528,DB00215,10003246,48,11055,16,5260,0.230880799,1.427391784,0.79550757,2.69553312,0.386972856,DB0021510003246_,0.949400729,0.355848851,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,101531,DB00215,10005750,77,11026,27,5249,0.206152425,1.357654721,0.864439956,2.192585694,0.356642223,DB0021510005750_,1.031022176,0.305758741,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,citalopram,DB00215
,101532,DB06643,10005750,113,52308,26,7489,0.038810232,0.622253669,0.403097913,0.994030377,0.103267393,DB0664310005750_,2.270433605,-0.474407441,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,denosumab,DB06643
,101534,DB00007,10006002,27,1920,43,4409,0.150632284,1.441816081,0.854008084,2.395048632,0.28479551,DB0000710006002_,1.255983865,0.365903487,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,leuprolide,DB00007
,101535,DB06643,10006002,950,51471,80,7435,9.31965886503303e-07,1.715331464,1.362430576,2.185776234,1.3474545284235e-05,DB0664310006002_,11.21470819,0.539606335,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,101536,DB00007,10025482,14,1933,65,4387,0.01342176,0.488868275,0.252711853,0.88282491,0.045001716,DB0000710025482_,3.101054668,-0.715662201,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,leuprolide,DB00007
,101555,DB01233,10021097,76,3345,52,1674,0.088429257,0.731442745,0.504690357,1.067265775,0.192613468,DB0123310021097_,1.647069854,-0.312736332,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,metoclopramide,DB01233
,101563,DB01098,10009033,39,8110,39,7170,0.649503774,0.884101624,0.551766806,1.416610986,0.784287431,DB0109810009033_,0.242979705,-0.123183263,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,101566,DB00635,10013774,99,32954,23,23771,9.48651756999945e-08,3.10479382,1.95620572,5.124612606,1.72383763793595e-06,DB0063510013774_,13.27095757,1.13294731,female,10013774,Dry eye,10015919,Eye disorders,Eye,prednisone,DB00635
,101571,DB01593,10019211,95,1038,23,675,8.57194537476975e-06,2.684692757,1.668229315,4.484509097,9.49288325998833e-05,DB0159310019211_,9.262383078,0.987566292,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,zinc,DB01593
,101575,DB00814,10023232,120,8167,29,3386,0.008328038,1.715496813,1.133155977,2.67570254,0.030740413,DB0081410023232_,3.482177107,0.539702726,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,101578,DB06674,10019211,132,4374,18,1472,0.000112513,2.467442513,1.49572886,4.308224441,0.00088281,DB0667410019211_,7.032400231,0.903182194,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,golimumab,DB06674
,101581,DB00787,10005483,65,16935,81,17167,0.245493347,0.813468787,0.577301465,1.142400237,0.40433565,DB0078710005483_,0.90550993,-0.206447721,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,acyclovir,DB00787
,101589,DB00695,10011878,58,27991,33,20495,0.288194558,1.286888981,0.825020111,2.037913807,0.453197366,DB0069510011878_,0.791427562,0.252227663,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,furosemide,DB00695
,101590,DB00722,10011878,36,25367,33,25999,0.718110217,1.118085325,0.677379677,1.851135078,0.833522203,DB0072210011878_,0.182094939,0.111617691,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,lisinopril,DB00722
,101604,DB00999,10037884,114,21316,51,12188,0.167616253,1.278100886,0.910205858,1.816319533,0.307699354,DB0099910037884_,1.178632096,0.245375293,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,101616,DB00661,10003673,36,3492,16,1579,1,1.017402774,0.548466869,1.969798376,1,DB0066110003673_,0,0.01725308,NA,10003673,Atrioventricular block complete,10007541,Cardiac disorders,Card,verapamil,DB00661
,101625,DB00334,10001488,25,2824,84,2728,4.87035489507504e-09,0.287539504,0.175663255,0.455639281,1.17231939942351e-07,DB0033410001488_,15.95911147,-1.246395024,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,101629,DB00334,10022437,69,2780,52,2760,0.142213958,1.31730886,0.902088673,1.933700702,0.272873487,DB0033410022437_,1.298747009,0.275590913,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,101631,DB00334,10061422,22,2827,41,2771,0.015709713,0.526017714,0.297588442,0.906649982,0.051117828,DB0033410061422_,2.973621967,-0.642420389,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,101632,DB01224,10061422,58,8050,88,5829,1.41989279330474e-05,0.477267154,0.335977144,0.673683148,0.000147897,DB0122410061422_,8.818992486,-0.739678873,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,101658,DB01098,10021143,29,8120,41,7168,0.054970304,0.624415651,0.373811506,1.030620357,0.134290109,DB0109810021143_,2.007752826,-0.470939025,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,101659,DB01409,10021143,84,5947,58,3908,0.795771453,0.951741105,0.671255618,1.357312258,0.889397596,DB0140910021143_,0.117210904,-0.04946223,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,101686,DB00437,10051792,25,6896,43,11503,1,0.969807272,0.567076693,1.625754777,1,DB0043710051792_,0,-0.030657916,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,allopurinol,DB00437
,101687,DB00741,10051792,59,4035,46,3128,1,0.994300199,0.662750387,1.499778482,1,DB0074110051792_,0,-0.005716107,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocortisone,DB00741
,101688,DB00927,10051792,103,7394,73,4943,0.699383054,0.943257941,0.690514205,1.294046139,0.819274175,DB0092710051792_,0.199336483,-0.058415502,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,famotidine,DB00927
,101689,DB01234,10051792,172,31453,134,32754,0.013592215,1.336663866,1.059668517,1.689029701,0.045457266,DB0123410051792_,3.090982598,0.290176857,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,101691,DB00646,10033425,76,3377,34,1966,0.230627712,1.301268455,0.854039451,2.01944557,0.386647282,DB0064610033425_,0.950242417,0.263339523,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,nystatin,DB00646
,101692,DB00698,10033425,78,3070,6,423,0.23146466,1.790966239,0.77993446,5.060679332,0.387704228,DB0069810033425_,0.947512529,0.582755272,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,nitrofurantoin,DB00698
,101694,DB11750,10033425,49,2451,21,1492,0.213442175,1.420254027,0.832083253,2.503675891,0.365555444,DB1175010033425_,1.006337317,0.350835748,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,clobetasol,DB11750
,101695,DB00196,10046571,108,4975,27,3258,1.86252516136248e-06,2.619221728,1.700384589,4.164828551,2.48889038466765e-05,DB0019610046571_,10.60108848,0.962877223,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,fluconazole,DB00196
,101697,DB11750,10046571,46,2454,7,1506,0.000147253,4.031754089,1.80174263,10.61504176,0.001108561,DB1175010046571_,6.804692387,1.394201539,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,clobetasol,DB11750
,101698,DB00698,10053762,66,3082,12,417,0.375687027,0.744229584,0.39463512,1.525898792,0.545501091,DB0069810053762_,0.606050474,-0.295405711,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,nitrofurantoin,DB00698
,101699,DB11750,10053762,51,2449,23,1490,0.276116544,1.348989778,0.805705153,2.323014851,0.439515737,DB1175010053762_,0.822081757,0.299356,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,clobetasol,DB11750
,101712,DB06643,10001760,491,51930,14,7501,7.62962564853685e-15,5.065798843,2.98811437,9.340316858,4.57342554553686e-13,DB0664310001760_,28.41334371,1.622511844,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,101713,DB06643,10028810,206,52215,27,7488,0.7659771,1.094157098,0.729815013,1.701834917,0.870989683,DB0664310028810_,0.138125147,0.089984293,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,denosumab,DB06643
,101714,DB00153,10033557,82,7341,12,3427,2.93298946339749e-05,3.189699068,1.728074116,6.433004069,0.000278116,DB0015310033557_,8.187473914,1.159926576,female,10033557,Palpitations,10007541,Cardiac disorders,Card,ergocalciferol,DB00153
,101715,DB01012,10054112,2419,8213,1944,6741,0.545009254,1.021323018,0.953772422,1.093669951,0.699866541,DB0101210054112_,0.356865617,0.021098863,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,cinacalcet,DB01012
,101723,DB00641,10037855,36,14088,29,12446,0.803719588,1.096657232,0.653414904,1.85541391,0.893803439,DB0064110037855_,0.112269395,0.092266673,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,101724,DB00682,10037855,52,19407,24,16340,0.015100491,1.824221667,1.103975509,3.095513145,0.049589265,DB0068210037855_,3.003980906,0.601153412,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,101726,DB00999,10037855,47,21383,22,12217,0.531255514,1.220542997,0.720719322,2.12807504,0.688107584,DB0099910037855_,0.373810081,0.199295839,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,101732,DB00455,10022004,70,9331,19,5099,0.005248877,2.013179308,1.197009855,3.544805863,0.021266549,DB0045510022004_,3.85061992,0.699715218,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,101733,DB00455,10028391,43,9358,16,5102,0.219846411,1.465193915,0.807698353,2.789528696,0.373255792,DB0045510028391_,0.985491325,0.381987599,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,101735,DB00455,10028836,60,9341,12,5106,0.000724738,2.732948721,1.453585612,5.586859838,0.004213146,DB0045510028836_,5.469545623,1.005381144,female,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,101740,DB08889,10013573,53,3112,53,3832,0.325231784,1.231320558,0.822786348,1.8427956,0.493629317,DB0888910013573_,0.705970415,0.208087218,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,carfilzomib,DB08889
,101748,DB00814,10060800,54,8233,14,3401,0.140714506,1.593329249,0.871382725,3.110450902,0.270841385,DB0081410060800_,1.306221924,0.465825694,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,meloxicam,DB00814
,101749,DB00924,10060800,62,10100,12,4239,0.010428347,2.168368345,1.155806273,4.42567336,0.036800579,DB0092410060800_,3.302241708,0.77397497,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,cyclobenzaprine,DB00924
,101753,DB00295,10022086,45,14618,12,9590,0.004066992,2.460059508,1.279025037,5.111410914,0.017321223,DB0029510022086_,4.055822794,0.90018554,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,101754,DB00381,10022086,206,29154,71,22816,3.89877200624029e-10,2.270580162,1.724757937,3.019062775,1.16785438386354e-08,DB0038110022086_,18.26551254,0.820035377,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,101755,DB00695,10022086,136,27913,25,20503,4.74825087679524e-13,3.99572693,2.593435765,6.393588348,2.21880487638334e-11,DB0069510022086_,24.53146732,1.385225523,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,101756,DB00787,10022086,42,16958,12,17236,2.92836061760248e-05,3.55689952,1.837781198,7.426165224,0.000277777,DB0078710022086_,8.188692546,1.268889244,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,101757,DB00959,10022086,71,8007,14,4988,1.56381537459369e-05,3.15902781,1.762435993,6.076617102,0.000160597,DB0095910022086_,8.736610369,1.150264325,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,101758,DB01136,10022086,46,9838,19,11096,0.000147804,2.730512188,1.56739111,4.938335804,0.001112073,DB0113610022086_,6.80152986,1.004489206,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,101759,DB11089,10022086,42,10133,10,8397,0.000121905,3.480149482,1.717027513,7.785091235,0.000945213,DB1108910022086_,6.964100166,1.247075247,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,101761,DB01593,10033371,52,1081,18,680,0.032519914,1.816698485,1.03493377,3.329086206,0.090233921,DB0159310033371_,2.405349855,0.597020835,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,zinc,DB01593
,101770,DB00051,10033775,298,25433,109,11311,0.084019899,1.215862405,0.972005216,1.530152428,0.185087416,DB0005110033775_,1.686927048,0.195453624,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,101771,DB00421,10033775,65,8838,12,5240,4.42544188533216e-05,3.21128707,1.717263238,6.538119796,0.000398229,DB0042110033775_,7.82848292,1.166671813,female,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,101776,DB13961,10042674,72,9385,27,6387,0.007402488,1.814742277,1.149948599,2.941982621,0.028003011,DB1396110042674_,3.575443226,0.595943462,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,101778,DB00373,10003549,43,1789,30,1257,1,1.007096815,0.613518245,1.672618486,1,DB0037310003549_,0,0.007071751,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,timolol,DB00373
,101780,DB00448,10003658,38,5107,26,3098,0.698109049,0.886611984,0.523318308,1.524014951,0.81843832,DB0044810003658_,0.200357242,-0.12034784,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,lansoprazole,DB00448
,101782,DB11133,10021097,28,2403,30,1544,0.057899575,0.599794707,0.343801774,1.043381181,0.139520564,DB1113310021097_,1.969543274,-0.511167838,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,omega-3 fatty acids,DB11133
,101797,DB00316,10037437,70,65404,53,36900,0.110584116,0.745174523,0.513952749,1.08595802,0.22694437,DB0031610037437_,1.483050358,-0.294136829,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,101808,DB00706,10043607,8,1067,136,15789,0.863445898,0.870447373,0.367370152,1.770825539,0.937005364,DB0070610043607_,0.065066272,-0.138747978,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,tamsulosin,DB00706
,101810,DB01137,10043607,45,7727,54,5539,0.013708596,0.597401788,0.392437586,0.905569787,0.0457795,DB0113710043607_,3.083918885,-0.515165381,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,levofloxacin,DB01137
,101816,DB06228,10061024,65,15847,76,16000,0.39962227,0.86352523,0.609931537,1.219542443,0.569496129,DB0622810061024_,0.563003293,-0.146732164,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,101820,DB01136,10010264,145,9739,119,10996,0.010884582,1.375725809,1.070341391,1.771063163,0.0380935,DB0113610010264_,3.267711622,0.318981453,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,101823,DB00338,10020646,65,33609,74,22198,0.001688147,0.580173529,0.409054239,0.821064734,0.008461661,DB0033810020646_,4.772209786,-0.544428033,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,101824,DB00451,10020646,66,47205,63,15356,3.44113505532098e-09,0.340804157,0.237477997,0.489454328,8.57348198380208e-08,DB0045110020646_,16.27200679,-1.076447286,male,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,101838,DB00829,10038435,43,8009,31,4423,0.273921091,0.766065916,0.470856953,1.25951842,0.437000235,DB0082910038435_,0.827821546,-0.26648706,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,diazepam,DB00829
,101839,DB00950,10011906,97,4621,77,1979,0.000108032,0.539524435,0.393979226,0.741010562,0.000852102,DB0095010011906_,7.067803778,-0.617067203,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,101841,DB01012,10003549,48,10584,59,8626,0.040289787,0.663076441,0.442887213,0.9884183,0.106225693,DB0101210003549_,2.242189268,-0.410865,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,101847,DB01012,10061428,320,10312,182,8503,7.37758433933268e-05,1.449768749,1.201956413,1.75291597,0.000613962,DB0101210061428_,7.395578002,0.37140406,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,cinacalcet,DB01012
,101852,DB05676,10042674,128,47001,35,25294,0.000202587,1.968105653,1.344527829,2.949213599,0.001456905,DB0567610042674_,6.531441108,0.677071483,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,101854,DB00887,10012174,69,2272,39,1776,0.11622453,1.382883078,0.915720893,2.114591699,0.235467995,DB0088710012174_,1.446180276,0.324170507,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,bumetanide,DB00887
,101856,DB01065,10012174,54,4277,57,2994,0.03274863,0.663232578,0.447132788,0.982710883,0.090720108,DB0106510012174_,2.399976246,-0.410629554,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,melatonin,DB01065
,101857,DB01118,10012174,23,3040,39,4670,0.794536841,0.905949811,0.515450617,1.558614566,0.888754638,DB0111810012174_,0.11793408,-0.098771371,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,amiodarone,DB01118
,101858,DB01377,10012174,97,3699,46,2624,0.025555875,1.495777501,1.038634278,2.181397392,0.074728688,DB0137710012174_,2.593891224,0.402646139,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,magnesium oxide,DB01377
,101860,DB00887,10018884,70,2271,52,1763,0.853289585,1.045029444,0.715364653,1.534828245,0.928379352,DB0088710018884_,0.074314846,0.044045061,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,bumetanide,DB00887
,101861,DB01065,10018884,48,4283,32,3019,0.909206915,1.057320505,0.660388123,1.713414219,0.959182187,DB0106510018884_,0.041674246,0.055737882,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,melatonin,DB01065
,101862,DB01068,10018884,80,13683,41,6799,0.922906762,0.969521773,0.656584805,1.451043002,0.966266525,DB0106810018884_,0.034315577,-0.030952347,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,clonazepam,DB01068
,101865,DB14500,10018884,124,7685,49,4024,0.106464637,1.325058665,0.942395701,1.88848906,0.220800299,DB1450010018884_,1.51049661,0.281456734,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,potassium,DB14500
,101869,DB01068,10020993,43,13720,24,6816,0.696900854,0.890097283,0.527673151,1.534815629,0.817641839,DB0106810020993_,0.201330888,-0.116424516,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,clonazepam,DB01068
,101888,DB00542,10028813,113,1573,48,1376,2.98724634312597e-05,2.058874426,1.444183331,2.972898367,0.00028275,DB0054210028813_,8.170946231,0.722159438,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,benazepril,DB00542
,101889,DB01020,10028813,97,1716,75,1803,0.05125737,1.358784711,0.987252772,1.876082004,0.127379187,DB0102010028813_,2.06058692,0.306590706,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,isosorbide mononitrate,DB01020
,101890,DB00175,10047700,234,7897,120,5986,0.000493167,1.478076715,1.177890595,1.862570628,0.003058684,DB0017510047700_,5.789770572,0.390741726,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,101894,DB00264,10050953,55,29552,47,24845,1,0.983820273,0.654129895,1.484872516,1,DB0026410050953_,0,-0.016312048,NA,10050953,Lower gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,101934,DB01202,10005750,31,6683,25,5693,0.893571217,1.056319661,0.60281233,1.868234436,0.955670726,DB0120210005750_,0.045341854,0.054790849,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,levetiracetam,DB01202
,101944,DB00999,10045555,30,21400,31,12208,0.022997332,0.552102765,0.322697268,0.943346256,0.068898943,DB0099910045555_,2.67511444,-0.594021082,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,101955,DB00542,10013700,60,1626,21,1403,0.000258269,2.464532002,1.468863551,4.288740516,0.001785298,DB0054210013700_,6.328169932,0.902001932,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,benazepril,DB00542
,101956,DB01076,10005728,40,25707,45,25538,0.588696208,0.883047907,0.561847876,1.383413141,0.735582809,DB0107610005728_,0.307092157,-0.124375826,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,atorvastatin,DB01076
,101958,DB01136,10027175,105,9779,62,11053,4.58488000835829e-05,1.914104584,1.383564723,2.667536504,0.000410329,DB0113610027175_,7.798551748,0.649249933,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,101960,DB01076,10033557,184,25563,75,25508,9.06942545769117e-12,2.448149163,1.860650296,3.248275091,3.48778124587289e-10,DB0107610033557_,21.77658514,0.895332295,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,101967,DB00377,10011224,58,1061,41,682,0.672817183,0.909361097,0.591734514,1.408383489,0.801411037,DB0037710011224_,0.221381309,-0.095013017,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,palonosetron,DB00377
,101969,DB00377,10013968,122,997,52,671,0.008880688,1.578630117,1.114222942,2.261959264,0.032373468,DB0037710013968_,3.430416095,0.456557456,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,palonosetron,DB00377
,101973,DB00203,10069327,8,13870,61,8877,2.28923542080328e-17,0.083947693,0.034663824,0.176186782,1.84578383545442e-15,DB0020310069327_,33.92587236,-2.477561382,male,10069327,Product quality issue,10077536,Product issues,Prod,sildenafil,DB00203
,101974,DB00737,10003549,120,2681,44,888,0.580158532,0.903341264,0.628724199,1.318083746,0.728733012,DB0073710003549_,0.316447852,-0.101654874,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,meclizine,DB00737
,101990,DB00264,10017853,59,29548,37,24855,0.182502287,1.341321775,0.874201183,2.082198781,0.327043878,DB0026410017853_,1.117660934,0.293655527,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,102002,DB00695,10022972,56,27993,51,20477,0.281386624,0.803229606,0.539497029,1.198243181,0.445341342,DB0069510022972_,0.80891423,-0.219114671,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,furosemide,DB00695
,102003,DB00722,10022972,23,25380,30,26002,0.411722895,0.785461134,0.435589932,1.398872309,0.581194721,DB0072210022972_,0.54266943,-0.241484301,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,lisinopril,DB00722
,102005,DB01076,10022972,29,25718,34,25549,0.530873198,0.847339963,0.497848911,1.43343564,0.687850894,DB0107610022972_,0.374183189,-0.165653291,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,atorvastatin,DB01076
,102006,DB00319,10007515,41,1351,34,1819,0.044316674,1.623332045,0.999177172,2.652602461,0.114241532,DB0031910007515_,2.169440368,0.484480855,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,piperacillin,DB00319
,102007,DB01225,10007515,70,4974,63,4577,0.930496221,1.022428481,0.715185659,1.464257012,0.971696754,DB0122510007515_,0.028711504,0.022180661,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,enoxaparin,DB01225
,102011,DB00761,10038687,61,15246,48,8577,0.089116101,0.714973472,0.481329089,1.067321984,0.193828161,DB0076110038687_,1.640783278,-0.335509839,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,102016,DB01175,10021097,173,10551,88,4804,0.41939393,0.895114214,0.686937121,1.173322518,0.588414538,DB0117510021097_,0.530323583,-0.110803956,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,escitalopram,DB01175
,102032,DB00338,10017853,73,33601,50,22222,0.85410211,0.965549015,0.66439709,1.413334312,0.928955765,DB0033810017853_,0.073694157,-0.035058412,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,102035,DB00682,10017853,40,19419,47,16317,0.131442966,0.715127418,0.456860567,1.114570997,0.257814967,DB0068210017853_,1.355513133,-0.335294546,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,102038,DB00682,10022972,33,19426,25,16339,0.792210171,1.110205087,0.64013001,1.948404071,0.88743507,DB0068210022972_,0.119419921,0.104544761,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,warfarin,DB00682
,102041,DB00338,10027141,30,33644,28,22244,0.226738716,0.708403502,0.408845394,1.230885728,0.381856616,DB0033810027141_,0.962710091,-0.34474143,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,102056,DB01136,10046274,23,9861,51,11064,0.006910012,0.506026057,0.294923705,0.843867695,0.026524959,DB0113610046274_,3.629669144,-0.681167116,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,102057,DB00584,10003239,44,2037,28,1846,0.15425864,1.423953516,0.862874595,2.385726521,0.289868048,DB0058410003239_,1.238329468,0.353437169,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,enalapril,DB00584
,102060,DB00695,10009802,55,27994,55,20473,0.101454047,0.731349736,0.493746429,1.083224442,0.213064846,DB0069510009802_,1.546158717,-0.312863499,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,furosemide,DB00695
,102063,DB01377,10015090,31,3765,23,2647,0.88996283,0.947621602,0.533556535,1.705987295,0.954386794,DB0137710015090_,0.046686245,-0.05380001,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium oxide,DB01377
,102074,DB00682,10024378,25,19434,46,16318,0.001728299,0.456345025,0.268563398,0.758800281,0.008619358,DB0068210024378_,4.753744674,-0.784506121,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,warfarin,DB00682
,102086,DB00695,10043089,48,28001,28,20500,0.355098278,1.255050809,0.771365456,2.078319637,0.524891985,DB0069510043089_,0.644562781,0.227176057,NA,10043089,Tachypnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,102089,DB00264,10054889,36,29571,29,24863,0.901363248,1.043746955,0.62206359,1.765343548,0.956927891,DB0026410054889_,0.044027239,0.04281708,NA,10054889,Transaminases increased,10022891,Investigations,Inv,metoprolol,DB00264
,102093,DB00682,10063743,54,19405,43,16321,0.838576473,1.056241886,0.694089083,1.616097475,0.917116693,DB0068210063743_,0.08652056,0.054717218,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,102094,DB00555,10001497,100,6947,93,3393,1.31906886645272e-05,0.525188609,0.390789036,0.706428597,0.000138521,DB0055510001497_,8.88449096,-0.643997826,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,102097,DB00555,10041962,48,6999,37,3449,0.048531544,0.639302646,0.406877066,1.011732742,0.122311868,DB0055510041962_,2.1011812,-0.447377312,NA,10041962,Status epilepticus,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,102098,DB00555,10045555,53,6994,11,3475,0.007144923,2.393768856,1.233780554,5.089725909,0.027233801,DB0055510045555_,3.60329638,0.872869051,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,102099,DB01156,10045555,61,13561,38,6290,0.15986297,0.744557952,0.488026874,1.148937016,0.297286651,DB0115610045555_,1.213058451,-0.294964589,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,102109,DB00904,10061169,32,23037,32,14424,0.071227082,0.626153778,0.371207762,1.056066927,0.163404465,DB0090410061169_,1.811526772,-0.468159287,NA,10061169,Embolism,10047065,Vascular disorders,Vasc,ondansetron,DB00904
,102116,DB01069,10001497,31,6669,25,2370,0.003356127,0.440706531,0.251250779,0.780263555,0.014804908,DB0106910001497_,4.21279654,-0.819376087,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,promethazine,DB01069
,102117,DB00182,10028810,53,5141,21,2831,0.223336079,1.389734883,0.82219258,2.430915913,0.377662688,DB0018210028810_,0.97375384,0.329112997,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,amphetamine,DB00182
,102118,DB01104,10028810,159,15304,46,7240,0.002603728,1.635175382,1.169556763,2.325399458,0.012042756,DB0110410028810_,4.41929192,0.491750066,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,sertraline,DB01104
,102121,DB00437,10038063,28,6893,54,11492,0.569200022,0.864457483,0.526724927,1.390556392,0.720164745,DB0043710038063_,0.328275281,-0.145653156,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,102125,DB00682,10050953,30,19429,50,16314,0.003242183,0.50381909,0.309160849,0.808337753,0.014410009,DB0068210050953_,4.239832253,-0.685538023,NA,10050953,Lower gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,102134,DB00338,10013036,36,33638,24,22248,1,0.992091204,0.575593565,1.738684178,1,DB0033810013036_,0,-0.007940237,NA,10013036,Diplopia,10015919,Eye disorders,Eye,omeprazole,DB00338
,102143,DB00275,10012174,34,2026,23,1214,0.680006922,0.885825112,0.504100623,1.58293994,0.806455783,DB0027510012174_,0.215106209,-0.121235738,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,olmesartan,DB00275
,102144,DB01307,10012174,42,2482,36,2033,0.908739989,0.955600705,0.595122809,1.54146627,0.95913476,DB0130710012174_,0.041723693,-0.045415126,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,insulin detemir,DB01307
,102145,DB01307,10017577,38,2486,25,2044,0.444921034,1.249689637,0.73222858,2.167819381,0.612964483,DB0130710017577_,0.489448284,0.22289523,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,insulin detemir,DB01307
,102146,DB01377,10017577,45,3751,27,2643,0.548941825,1.174300803,0.710989002,1.973671401,0.703387324,DB0137710017577_,0.35184758,0.160672909,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,102147,DB00169,10020646,44,38647,58,18117,3.07923530946315e-07,0.355634097,0.234611261,0.535655832,5.00462183144492e-06,DB0016910020646_,12.20514871,-1.033852895,male,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,102156,DB00695,10021137,47,28002,47,20481,0.143362826,0.731426478,0.477410291,1.120493148,0.274547779,DB0069510021137_,1.292629976,-0.312758572,NA,10021137,Hypovolaemia,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,102161,DB01104,10033661,34,15429,17,7269,0.880793415,0.942255025,0.511605732,1.799699398,0.950123172,DB0110410033661_,0.051163648,-0.059479314,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,sertraline,DB01104
,102162,DB01136,10033661,42,9842,59,11056,0.273834721,0.799681565,0.52465513,1.209342281,0.436887671,DB0113610033661_,0.828079162,-0.223541675,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,carvedilol,DB01136
,102165,DB00421,10040047,126,8777,79,5173,0.662905273,0.94003062,0.702405419,1.264444917,0.794494909,DB0042110040047_,0.230048701,-0.06184283,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,spironolactone,DB00421
,102167,DB01307,10040047,20,2504,38,2031,0.002026799,0.426971587,0.234593729,0.755157565,0.009830943,DB0130710040047_,4.622220411,-0.851037808,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,insulin detemir,DB01307
,102197,DB01036,10003549,43,1458,15,407,0.518668242,0.800326895,0.430617607,1.567416839,0.677890822,DB0103610003549_,0.388769033,-0.222735016,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,tolterodine,DB01036
,102222,DB01036,10016256,80,1421,18,404,0.452366952,1.263432027,0.740126151,2.266686295,0.619978606,DB0103610016256_,0.478070308,0.233831849,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tolterodine,DB01036
,102224,DB00451,10021015,159,47112,44,15375,0.369429999,1.179303794,0.839369278,1.687425547,0.539081082,DB0045110021015_,0.617889289,0.164924259,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,102225,DB00588,10021015,74,16450,28,8440,0.208058345,1.355969042,0.866257127,2.177936301,0.358857811,DB0058810021015_,1.024829039,0.304516359,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,fluticasone propionate,DB00588
,102228,DB06228,10021015,42,15870,21,16055,0.007815666,2.023259596,1.170939295,3.598144951,0.029230901,DB0622810021015_,3.532528868,0.704709872,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,rivaroxaban,DB06228
,102230,DB00390,10046571,86,4059,39,3262,0.0026931,1.772009505,1.196686518,2.665569221,0.012380961,DB0039010046571_,4.391595426,0.572114216,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,digoxin,DB00390
,102241,DB00588,10070863,37,16487,18,8450,1,1.053520858,0.58440284,1.966994382,1,DB0058810070863_,0,0.052137753,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,102242,DB01050,10070863,549,17559,347,9024,0.003292127,0.813118173,0.707787157,0.935063205,0.014588815,DB0105010070863_,4.227500126,-0.206878826,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,102243,DB00761,10013709,374,14933,199,8426,0.537594892,1.060459343,0.888595067,1.268593339,0.693745088,DB0076110013709_,0.365650695,0.058702157,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,102244,DB00316,10015946,68,65406,19,36934,0.005077248,2.02097479,1.200586541,3.560566642,0.020709459,DB0031610015946_,3.877164731,0.703579964,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,acetaminophen,DB00316
,102246,DB00331,10015967,56,24890,32,20720,0.107454946,1.456795194,0.926884819,2.32573704,0.222345372,DB0033110015967_,1.503523377,0.376238951,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,metformin,DB00331
,102248,DB00331,10023644,43,24903,31,20721,0.561411992,1.154152283,0.710262908,1.895367036,0.713805322,DB0033110023644_,0.337145012,0.14336612,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,metformin,DB00331
,102252,DB00331,10041232,37,24909,17,20735,0.040837817,1.811717642,0.994617129,3.432183349,0.107315372,DB0033110041232_,2.231983379,0.594275369,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,102254,DB00471,10041232,44,14145,14,5451,0.659771903,1.21112894,0.650798204,2.395002121,0.792184385,DB0047110041232_,0.232961104,0.191552933,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,102260,DB00182,10001760,42,5152,10,2842,0.013232416,2.316638699,1.14161121,5.186320214,0.044497415,DB0018210001760_,3.112324185,0.840117298,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,amphetamine,DB00182
,102261,DB00295,10001760,47,14616,23,9579,0.2723356,1.339233838,0.796468314,2.312464469,0.43528983,DB0029510001760_,0.831743195,0.292097688,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,morphine,DB00295
,102262,DB00813,10001760,51,10521,11,10157,5.64244910687441e-07,4.475493787,2.30182146,9.528041706,8.64287731784346e-06,DB0081310001760_,11.65877501,1.498616689,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,fentanyl,DB00813
,102279,DB00182,10025482,146,5048,29,2823,3.53837224455555e-08,2.815130787,1.874232103,4.362891616,7.03466890549462e-07,DB0018210025482_,14.16724503,1.035008721,female,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,102280,DB00956,10025482,191,5623,78,3389,0.003945232,1.475790855,1.124173008,1.952854479,0.016887944,DB0095610025482_,4.081155286,0.389194019,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,102289,DB00182,10049848,47,5147,14,2838,0.043651587,1.85096392,0.999713963,3.647041322,0.112897961,DB0018210049848_,2.181270872,0.615706541,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,102315,DB00620,10043071,40,4788,14,3118,0.049735087,1.860466505,0.988959633,3.708584236,0.12452722,DB0062010043071_,2.083230953,0.620827265,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,triamcinolone,DB00620
,102317,DB00620,10047895,103,4725,56,3076,0.325120434,1.197330218,0.853623567,1.694469877,0.493548404,DB0062010047895_,0.706134342,0.18009426,NA,10047895,Weight decreased,10022891,Investigations,Inv,triamcinolone,DB00620
,102318,DB00073,10047899,45,7361,20,6387,0.012331727,1.952154002,1.127967489,3.493941602,0.042066311,DB0007310047899_,3.168508083,0.668933379,NA,10047899,Weight increased,10022891,Investigations,Inv,rituximab,DB00073
,102356,DB00328,10012735,27,733,38,777,0.310891089,0.753313788,0.437527743,1.281159226,0.478370981,DB0032810012735_,0.737368736,-0.28327342,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,indomethacin,DB00328
,102359,DB00328,10028813,44,716,26,789,0.014125547,1.864100151,1.109609955,3.188471436,0.046927453,DB0032810028813_,3.059152432,0.622778444,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,indomethacin,DB00328
,102397,DB00656,10028735,77,11936,18,6601,0.000524181,2.365655382,1.400866248,4.204432651,0.003209432,DB0065610028735_,5.741661307,0.861055101,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,102399,DB00722,10028735,123,25280,64,25968,6.77816996209111e-06,1.974141004,1.447169404,2.715304849,7.7261143735284e-05,DB0072210028735_,9.468319397,0.680133369,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,102404,DB00448,10028810,64,5081,25,3099,0.061811567,1.561313656,0.967106693,2.593546095,0.146794095,DB0044810028810_,1.918724387,0.445527554,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,lansoprazole,DB00448
,102417,DB00656,10060800,57,11956,18,6601,0.039548045,1.748292586,1.013003129,3.159381713,0.1047534,DB0065610060800_,2.256146258,0.558639647,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,trazodone,DB00656
,102429,DB00958,10027457,40,4554,16,2569,0.266408249,1.410234505,0.770504601,2.703149884,0.428552069,DB0095810027457_,0.847343033,0.343756006,NA,10027457,Metastases to liver,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,carboplatin,DB00958
,102443,DB00526,10002034,43,1555,50,1844,1,1.019831581,0.658368568,1.573977884,1,DB0052610002034_,0,0.019637497,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,oxaliplatin,DB00526
,102444,DB00650,10002034,51,2080,74,1940,0.017942783,0.642874913,0.438475321,0.936287852,0.056726732,DB0065010002034_,2.869509721,-0.44180511,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,leucovorin,DB00650
,102445,DB00762,10002034,43,1120,35,1334,0.106584477,1.463079269,0.907661632,2.372746439,0.220987812,DB0076210002034_,1.509647727,0.380543303,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,irinotecan,DB00762
,102463,DB00002,10037844,79,337,79,730,8.9280273845267e-06,2.164719666,1.522299136,3.078725892,9.83514515894199e-05,DB0000210037844_,9.226963254,0.772290868,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cetuximab,DB00002
,102480,DB00002,10053762,27,389,39,770,0.23055296,1.370066509,0.793744889,2.334420856,0.386558943,DB0000210053762_,0.950470918,0.314859286,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cetuximab,DB00002
,102488,DB00642,10053762,55,479,58,475,0.766367969,0.940382538,0.623880942,1.4161653,0.871350686,DB0064210053762_,0.137710759,-0.061468531,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,pemetrexed,DB00642
,102495,DB00186,10007882,84,16817,63,9945,0.1708133,0.78850812,0.561418772,1.112230667,0.311934385,DB0018610007882_,1.164962416,-0.237612574,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,lorazepam,DB00186
,102500,DB00186,10024384,39,16862,27,9981,0.52651219,0.855010121,0.509872302,1.453344767,0.684304436,DB0018610024384_,0.379352379,-0.156641973,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,lorazepam,DB00186
,102501,DB00497,10024384,40,19227,27,16348,0.391467807,1.259638936,0.753754036,2.135435191,0.561325586,DB0049710024384_,0.577454175,0.230825121,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,oxycodone,DB00497
,102513,DB00836,10015090,46,5489,18,4057,0.022006998,1.888720432,1.072275803,3.466467729,0.066642161,DB0083610015090_,2.708417859,0.635899579,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loperamide,DB00836
,102526,DB00343,10037660,153,8583,96,4999,0.595985854,0.928254409,0.712707474,1.213963071,0.741456274,DB0034310037660_,0.299139088,-0.074449436,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,102529,DB01075,10038063,41,19907,23,11074,1,0.991639958,0.580859763,1.732053444,1,DB0107510038063_,0,-0.008395184,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,102531,DB00982,10005425,49,3315,23,2078,0.274354092,1.335387123,0.795464897,2.303910712,0.43753169,DB0098210005425_,0.826606142,0.289221229,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,isotretinoin,DB00982
,102554,DB00441,10025482,58,2216,24,1870,0.003362491,2.038963462,1.241525248,3.445684583,0.014825644,DB0044110025482_,4.211396926,0.712441572,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,gemcitabine,DB00441
,102555,DB00530,10025482,47,1761,30,1238,0.726096292,1.101373114,0.67780606,1.814600567,0.839640177,DB0053010025482_,0.174781839,0.096557687,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,erlotinib,DB00530
,102556,DB01041,10025482,56,2989,33,3085,0.010397287,1.751303309,1.115744178,2.788613212,0.03672055,DB0104110025482_,3.304418738,0.560360259,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,thalidomide,DB01041
,102557,DB01101,10025482,115,7474,54,3854,0.623797186,1.098140021,0.786117151,1.55058788,0.763766695,DB0110110025482_,0.26949291,0.093617858,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,102565,DB00530,10047895,79,1729,49,1219,0.521656127,1.136603764,0.779567466,1.67124066,0.680376182,DB0053010047895_,0.385109425,0.128044661,NA,10047895,Weight decreased,10022891,Investigations,Inv,erlotinib,DB00530
,102566,DB00530,10012174,47,1761,31,1237,0.816808996,1.064982271,0.658315192,1.744712807,0.901922933,DB0053010012174_,0.103226203,0.062958152,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,erlotinib,DB00530
,102574,DB01050,10024378,33,18075,29,9342,0.043478879,0.588126774,0.346003948,1.004775523,0.112589759,DB0105010024378_,2.18400452,-0.530812752,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,ibuprofen,DB01050
,102579,DB06724,10000087,131,7798,33,3886,0.000298811,1.978130265,1.338735854,2.998334588,0.002011064,DB0672410000087_,6.209091571,0.682152088,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,102580,DB06724,10013968,337,7592,135,3784,0.035978928,1.244134982,1.011968944,1.536613925,0.097485425,DB0672410013968_,2.328052396,0.218440495,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,102581,DB06724,10035598,56,7873,24,3895,0.633903949,1.154342831,0.702600859,1.950663889,0.772344093,DB0672410035598_,0.258325112,0.143531204,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,102585,DB06724,10037377,63,7866,34,3885,0.666157976,0.915172873,0.592683577,1.435254119,0.796939781,DB0672410037377_,0.22697616,-0.088642299,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,102601,DB00588,10001949,62,16462,38,8430,0.397731509,0.83553064,0.548630517,1.287392063,0.5674477,DB0058810001949_,0.566606692,-0.179688259,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,102637,DB00112,10019465,20,5913,34,4057,0.001223783,0.403632224,0.219826988,0.722790766,0.006497101,DB0011210019465_,5.036399182,-0.907251151,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,bevacizumab,DB00112
,102649,DB01101,10020772,47,7542,16,3892,0.181929183,1.5158267,0.842729057,2.867922337,0.326321473,DB0110110020772_,1.11987227,0.415960966,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,capecitabine,DB01101
,102652,DB00112,10021789,46,5887,28,4063,0.636562123,1.133864572,0.692485619,1.887027564,0.774075798,DB0011210021789_,0.25608548,0.125631773,NA,10021789,Infection,10021881,Infections and infestations,Infec,bevacizumab,DB00112
,102653,DB01101,10021789,53,7536,20,3888,0.265391121,1.367167328,0.802392588,2.418068815,0.427399787,DB0110110021789_,0.850035435,0.312740955,NA,10021789,Infection,10021881,Infections and infestations,Infec,capecitabine,DB01101
,102679,DB00019,10010305,74,18938,25,9504,0.088436067,1.485451203,0.931999915,2.442108782,0.192620321,DB0001910010305_,1.647034279,0.395718567,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,pegfilgrastim,DB00019
,102683,DB00997,10010305,29,5302,35,3479,0.020252972,0.543737432,0.319978445,0.917500542,0.06242259,DB0099710010305_,2.77382805,-0.60928881,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,doxorubicin,DB00997
,102688,DB00019,10013968,179,18833,82,9447,0.510632136,1.094992188,0.837518783,1.441811459,0.671064732,DB0001910013968_,0.398889676,0.090747229,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pegfilgrastim,DB00019
,102704,DB00377,10016288,46,1073,28,695,0.903388924,1.064079768,0.644191611,1.785984987,0.957387878,DB0037710016288_,0.043546663,0.062110358,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,palonosetron,DB00377
,102707,DB00836,10016288,49,5486,46,4029,0.251597483,0.782338477,0.511235687,1.198969262,0.411603898,DB0083610016288_,0.887693805,-0.245467797,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,loperamide,DB00836
,102714,DB00019,10022437,79,18933,18,9511,0.00162505,2.204706821,1.308082015,3.912417069,0.008200121,DB0001910022437_,4.803606418,0.790594539,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,pegfilgrastim,DB00019
,102715,DB00377,10022437,33,1086,21,702,1,1.015777319,0.565216574,1.863589452,1,DB0037710022437_,0,0.015654151,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,palonosetron,DB00377
,102724,DB00019,10030124,36,18976,18,9511,1,1.002424036,0.554216923,1.876164097,1,DB0001910030124_,0,0.002421103,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,102725,DB00377,10030124,39,1080,25,698,1,1.00821792,0.588966724,1.754974015,1,DB0037710030124_,0,0.008184337,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,palonosetron,DB00377
,102787,DB00441,10000060,38,2236,19,1875,0.080874263,1.676897585,0.939338726,3.090625191,0.179838416,DB0044110000060_,1.715696521,0.516945411,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,gemcitabine,DB00441
,102791,DB00642,10003549,31,503,22,511,0.259487266,1.431016075,0.790047656,2.632473503,0.42062365,DB0064210003549_,0.866016789,0.358384734,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pemetrexed,DB00642
,102793,DB00642,10028813,51,483,30,503,0.020307892,1.769443464,1.084981671,2.929731768,0.062559968,DB0064210028813_,2.77162969,0.57066507,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pemetrexed,DB00642
,102795,DB00642,10047700,33,501,19,514,0.063610517,1.780949693,0.968712817,3.362172054,0.149992965,DB0064210047700_,1.897166887,0.577146757,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pemetrexed,DB00642
,102811,DB00073,10012818,31,7375,48,6359,0.012398344,0.55689156,0.342213739,0.894223365,0.042249365,DB0007310012818_,3.164165962,-0.585384744,NA,10012818,Diffuse large B-cell lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,rituximab,DB00073
,102812,DB00186,10001053,79,16822,59,9949,0.185598229,0.791931674,0.557521403,1.13018139,0.330910594,DB0018610001053_,1.105907048,-0.233280161,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,102813,DB00186,10010071,73,16828,36,9972,0.427069516,1.201662897,0.794930527,1.845849263,0.595703791,DB0018610010071_,0.518011731,0.183706345,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,102814,DB00193,10035669,31,19289,26,8676,0.021459704,0.536273539,0.307954338,0.940999771,0.065353763,DB0019310035669_,2.727940258,-0.623110914,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,tramadol,DB00193
,102815,DB00186,10039020,18,16883,79,9929,4.7303199415721e-19,0.134000487,0.075527097,0.225860149,4.49679781787424e-17,DB0018610039020_,37.64058103,-2.009911845,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,102820,DB01592,10003246,45,6231,12,3055,0.06541432,1.83848288,0.954766521,3.824007351,0.153156852,DB0159210003246_,1.876292709,0.60894071,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,iron,DB01592
,102854,DB00563,10009887,105,46541,125,15223,7.95756084672345e-22,0.274765044,0.209769859,0.359263112,9.93655519506536e-20,DB0056310009887_,43.75548146,-1.291838931,male,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,102855,DB00773,10009887,36,2287,40,2787,0.728193476,1.096743934,0.676815286,1.771519041,0.8414545,DB0077310009887_,0.172623337,0.092345731,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,etoposide,DB00773
,102856,DB00987,10009887,67,2037,110,2818,0.313242776,0.842654061,0.609018471,1.158691584,0.480835481,DB0098710009887_,0.732230102,-0.171198771,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,cytarabine,DB00987
,102880,DB00563,10035598,102,46544,79,15269,3.18909093236054e-08,0.423569318,0.312475034,0.575938976,6.41356198600588e-07,DB0056310035598_,14.25968084,-0.859038099,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,102887,DB00541,10038687,38,3096,48,4249,0.74223785,1.086483094,0.688859707,1.702855061,0.852277468,DB0054110038687_,0.159843138,0.082945961,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vincristine,DB00541
,102889,DB00541,10040070,88,3046,108,4189,0.463717251,1.120551954,0.832514589,1.50486998,0.630937858,DB0054110040070_,0.460547903,0.11382138,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,vincristine,DB00541
,102890,DB00563,10040070,99,46547,136,15212,3.86988929090204e-27,0.237918386,0.181603349,0.310700656,6.96712602817535e-25,DB0056310040070_,55.62342452,-1.435827582,male,10040070,Septic shock,10021881,Infections and infestations,Infec,methotrexate,DB00563
,102891,DB00773,10040070,69,2254,57,2770,0.029576221,1.487513184,1.02733697,2.161152357,0.083786275,DB0077310040070_,2.479486062,0.397105722,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,etoposide,DB00773
,102892,DB00997,10040070,66,5265,65,3449,0.024179108,0.665208954,0.463714317,0.954451177,0.071643315,DB0099710040070_,2.636055431,-0.407654071,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,doxorubicin,DB00997
,102894,DB00773,10047700,116,2207,137,2690,0.845949955,1.03202432,0.793568615,1.340243939,0.922538514,DB0077310047700_,0.080626154,0.031522233,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,etoposide,DB00773
,102901,DB00073,10000880,17,7389,41,6366,0.000286798,0.357253843,0.190078077,0.643569597,0.001945211,DB0007310000880_,6.242384701,-1.029308706,male,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,rituximab,DB00073
,102904,DB01234,10000880,26,31599,49,32839,0.014814334,0.551442194,0.328902539,0.90506126,0.048833054,DB0123410000880_,3.019347864,-0.595218262,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,102912,DB00451,10012267,80,47191,25,15394,0.910107208,1.04388669,0.658741984,1.708291407,0.959542868,DB0045110012267_,0.041298287,0.042950949,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,102926,DB00476,10012601,67,17190,32,6145,0.20787357,0.74847383,0.483696612,1.180093232,0.358729137,DB0047610012601_,1.025187668,-0.289719039,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,duloxetine,DB00476
,102927,DB00678,10012601,60,15539,43,10681,0.841292934,0.959090823,0.637077051,1.454863109,0.919014039,DB0067810012601_,0.084453881,-0.041769503,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,102928,DB00736,10012601,37,10554,16,5537,0.565262635,1.213174777,0.657788665,2.338067612,0.716865154,DB0073610012601_,0.332867525,0.193240706,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,esomeprazole,DB00736
,102937,DB06724,10012601,45,7884,14,3905,0.164525217,1.59200072,0.856882352,3.144517899,0.303444924,DB0672410012601_,1.192555153,0.464991539,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,calcium carbonate,DB06724
,102938,DB00370,10016173,139,4402,129,3534,0.260865279,0.865067912,0.672941038,1.112704283,0.422362491,DB0037010016173_,0.861891349,-0.144947264,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,mirtazapine,DB00370
,102956,DB01043,10035664,35,1366,56,1354,0.032606369,0.619617733,0.391396495,0.969105786,0.090438229,DB0104310035664_,2.403088215,-0.478652551,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,memantine,DB01043
,102957,DB00281,10040047,140,11318,98,5573,0.010111462,0.703424511,0.538363175,0.922101063,0.03588709,DB0028110040047_,3.327377671,-0.351794713,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,lidocaine,DB00281
,102958,DB00370,10040047,46,4495,58,3605,0.022580284,0.636115446,0.421258889,0.955681382,0.067920441,DB0037010040047_,2.689418247,-0.452375214,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,mirtazapine,DB00370
,102960,DB01156,10040047,52,13570,34,6294,0.130987449,0.709365551,0.451196076,1.128509677,0.257190192,DB0115610040047_,1.357939421,-0.343384299,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,bupropion,DB01156
,102962,DB06637,10040047,66,6096,26,1993,0.465268019,0.829910263,0.51824225,1.365548412,0.632077372,DB0663710040047_,0.458743468,-0.186437701,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,dalfampridine,DB06637
,102974,DB00046,10044565,48,5411,32,4660,0.311014032,1.291778979,0.807451656,2.09173366,0.478518136,DB0004610044565_,0.737061168,0.256020322,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,insulin lispro,DB00046
,102975,DB00047,10044565,88,9197,64,8454,0.165954956,1.263899017,0.904278497,1.774915009,0.305370574,DB0004710044565_,1.186229243,0.234201401,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,102976,DB00281,10044565,74,11384,40,5631,0.689732412,0.915094151,0.613864485,1.382016432,0.812888491,DB0028110044565_,0.207161336,-0.088728322,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,102977,DB00678,10044565,169,15430,87,10637,0.029603313,1.339108423,1.02664953,1.757103275,0.083831402,DB0067810044565_,2.478947611,0.292004037,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,losartan,DB00678
,102978,DB00915,10044565,54,1401,47,1004,0.355273662,0.823432802,0.541670764,1.255552351,0.52502562,DB0091510044565_,0.644308217,-0.194273333,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,amantadine,DB00915
,102980,DB01377,10044565,35,3761,28,2642,0.609582072,0.878110876,0.517545112,1.502478695,0.751961715,DB0137710044565_,0.285069867,-0.129982411,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,magnesium oxide,DB01377
,102981,DB01043,10046571,59,1342,43,1367,0.106955655,1.397481101,0.920235681,2.137139008,0.221556418,DB0104310046571_,1.507078015,0.334671402,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,memantine,DB01043
,102982,DB01377,10046571,162,3634,37,2633,6.96581069036462e-12,3.171786581,2.198989318,4.681809268,2.74243261852311e-10,DB0137710046571_,22.01700559,1.154295019,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,magnesium oxide,DB01377
,102983,DB00046,10047513,40,5419,20,4672,0.051046883,1.724209106,0.982843858,3.11792834,0.126979739,DB0004610047513_,2.063727744,0.544768456,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,insulin lispro,DB00046
,102984,DB00813,10047513,60,10512,17,10151,1.62630347448268e-06,3.407746817,1.960867554,6.235313334,2.21202519155381e-05,DB0081310047513_,10.71901699,1.226051315,female,10047513,Vision blurred,10015919,Eye disorders,Eye,fentanyl,DB00813
,102986,DB00924,10047513,98,10064,27,4224,0.060681367,1.523395849,0.984664619,2.430897423,0.144661572,DB0092410047513_,1.933358249,0.420941954,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,cyclobenzaprine,DB00924
,102987,DB00973,10047513,32,3819,21,3000,0.579783943,1.196990924,0.667707372,2.189030725,0.728446184,DB0097310047513_,0.316841528,0.179810844,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ezetimibe,DB00973
,102989,DB06724,10047513,73,7856,16,3903,0.002081561,2.26659763,1.304525841,4.178367586,0.010052148,DB0672410047513_,4.599968937,0.818279866,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,calcium carbonate,DB06724
,103013,DB01043,10047700,36,1365,21,1389,0.045099508,1.744076419,0.985273378,3.161717265,0.115765681,DB0104310047700_,2.156187124,0.556225143,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,memantine,DB01043
,103040,DB01224,10037377,53,8055,23,5894,0.036162484,1.686071243,1.014306762,2.885879432,0.097866758,DB0122410037377_,2.324148339,0.522401115,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,quetiapine,DB01224
,103053,DB00958,10047895,93,4501,51,2534,0.930238612,1.026618888,0.719246927,1.479659885,0.971504934,DB0095810047895_,0.028908932,0.026270769,NA,10047895,Weight decreased,10022891,Investigations,Inv,carboplatin,DB00958
,103080,DB00186,10013952,78,16823,26,9982,0.010712924,1.780026293,1.128234017,2.893590765,0.037607906,DB0018610013952_,3.280540991,0.576628135,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,103087,DB01229,10022437,55,5686,12,2697,0.012146976,2.17381034,1.14782862,4.467662012,0.041554403,DB0122910022437_,3.180751784,0.776481545,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,paclitaxel,DB01229
,103098,DB00112,10028334,46,5887,27,4064,0.55132609,1.176079243,0.714564517,1.970956882,0.70537644,DB0011210028334_,0.349023661,0.162186231,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,bevacizumab,DB00112
,103105,DB00997,10008531,43,5288,60,3454,0.00015552,0.468145369,0.308102806,0.706014293,0.001163468,DB0099710008531_,6.756350322,-0.758976414,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,103116,DB01075,10013946,101,19847,36,11061,0.020159934,1.563552426,1.058274933,2.357403981,0.062162456,DB0107510013946_,2.778004069,0.446960428,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,103117,DB01234,10013946,184,31441,126,32762,0.000261675,1.521653173,1.205795758,1.925287044,0.001803863,DB0123410013946_,6.317824837,0.419797357,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,103122,DB00904,10019974,111,22958,53,14403,0.107995505,1.313901834,0.938305141,1.860004339,0.223060023,DB0090410019974_,1.500314384,0.27300121,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,ondansetron,DB00904
,103123,DB01015,10019974,45,9842,33,9348,0.307029564,1.295171148,0.807482129,2.097069418,0.474108335,DB0101510019974_,0.746319428,0.258642847,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,103125,DB01075,10019974,94,19854,38,11059,0.1015725,1.377868571,0.93517812,2.0665617,0.213277849,DB0107510019974_,1.54515951,0.320537792,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,103126,DB01234,10019974,158,31467,163,32725,0.955415169,1.008077641,0.804346486,1.263158477,0.993161739,DB0123410019974_,0.006861749,0.008045192,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,103127,DB00073,10020751,130,7276,81,6326,0.021507417,1.395351158,1.046936445,1.868950577,0.065476309,DB0007310020751_,2.726066895,0.33314611,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,rituximab,DB00073
,103131,DB00904,10020751,198,22871,92,14364,0.018034524,1.35164977,1.049325696,1.751904761,0.05693118,DB0090410020751_,2.865912113,0.301325898,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ondansetron,DB00904
,103133,DB01015,10020751,112,9775,67,9314,0.00259228,1.592759807,1.164731609,2.192342313,0.012003537,DB0101510020751_,4.422553952,0.465468239,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,sulfamethoxazole,DB01015
,103135,DB01075,10020751,291,19657,128,10969,0.027223945,1.268641667,1.025601104,1.57636174,0.078494879,DB0107510020751_,2.544721895,0.237946774,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,diphenhydramine,DB01075
,103136,DB01234,10020751,243,31382,206,32682,0.032941906,1.228470537,1.015453353,1.487356052,0.09114985,DB0123410020751_,2.395250429,0.20576993,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,dexamethasone,DB01234
,103148,DB00073,10037377,20,7386,38,6369,0.003595384,0.453868418,0.249959448,0.800796429,0.015654245,DB0007310037377_,4.157013132,-0.789947952,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rituximab,DB00073
,103150,DB00541,10037377,20,3114,46,4251,0.059735074,0.593574036,0.33188382,1.026068237,0.142986652,DB0054110037377_,1.945003998,-0.521593328,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vincristine,DB00541
,103153,DB01075,10037377,108,19840,66,11031,0.578837217,0.909819701,0.663082534,1.25644528,0.727580497,DB0107510037377_,0.318030637,-0.094508829,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,103154,DB00073,10061822,108,7298,38,6369,6.03379852859778e-07,2.480064438,1.696289896,3.696441832,9.15430847470088e-06,DB0007310061822_,11.60128592,0.908284543,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,103156,DB00531,10061822,35,7217,35,6481,0.719209607,0.898026142,0.545060007,1.479514988,0.834225382,DB0053110061822_,0.181251671,-0.1075561,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,103159,DB00904,10061822,152,22917,88,14368,0.594672628,1.082937365,0.826738622,1.425791061,0.740481451,DB0090410061822_,0.300454695,0.079677132,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,103161,DB01075,10061822,72,19876,27,11070,0.092347414,1.485190241,0.941706148,2.406446232,0.19897957,DB0107510061822_,1.614553123,0.395542873,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,103167,DB00762,10061309,23,1140,32,1337,0.585707736,0.84301198,0.468130025,1.496033052,0.733075487,DB0076210061309_,0.310506599,-0.170774109,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,irinotecan,DB00762
,103211,DB00211,10037660,31,1405,31,1600,0.70004225,1.138740393,0.665749652,1.947845441,0.819772367,DB0021110037660_,0.198728578,0.129922733,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,midodrine,DB00211
,103213,DB00211,10061428,23,1413,34,1597,0.350349415,0.764627641,0.427870343,1.343742249,0.519999682,DB0021110061428_,0.65392708,-0.268366307,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,midodrine,DB00211
,103214,DB00112,10022437,64,5869,46,4045,0.845700358,0.958883178,0.644868296,1.435795441,0.922393987,DB0011210022437_,0.080782828,-0.041986028,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,bevacizumab,DB00112
,103238,DB00186,10020765,42,16859,20,9988,0.510949753,1.244151407,0.713851602,2.238246244,0.671297542,DB0018610020765_,0.39854281,0.218453697,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,103240,DB00186,10025197,44,16857,21,9987,0.443629133,1.241354726,0.722010377,2.19928392,0.611729712,DB0018610025197_,0.491464741,0.216203304,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,lorazepam,DB00186
,103241,DB00186,10028810,206,16695,68,9940,1.34025512968712e-05,1.803636609,1.363284399,2.411680928,0.000140437,DB0018610028810_,8.870752005,0.589804965,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,lorazepam,DB00186
,103257,DB00321,10037377,47,7400,16,2834,0.778247581,1.124968133,0.625204283,2.129185197,0.879072925,DB0032110037377_,0.128887421,0.117754709,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amitriptyline,DB00321
,103263,DB00043,10008479,99,6314,37,2263,0.844627885,0.95899085,0.64902896,1.444102649,0.92150127,DB0004310008479_,0.081751124,-0.041873745,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,103274,DB00635,10071408,206,32847,7,23787,3.15054633609893e-39,21.31121171,10.15531935,53.59826273,1.20017551368638e-36,DB0063510071408_,82.71059554,3.059233305,female,10071408,Maternal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,103300,DB00635,10027141,34,33019,32,23762,0.317979311,0.764636074,0.457661934,1.280285377,0.485943474,DB0063510027141_,0.721662971,-0.268355279,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,103305,DB00635,10031009,65,32988,19,23775,0.000337001,2.465548915,1.459732133,4.355404418,0.002222017,DB0063510031009_,6.109339948,0.902414466,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,103320,DB00590,10003549,23,753,72,1880,0.41783935,0.797628271,0.472186271,1.302300372,0.586897551,DB0059010003549_,0.532905004,-0.226112616,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,doxazosin,DB00590
,103323,DB00787,10012174,261,16739,240,17008,0.280106654,1.104969669,0.922496933,1.324011651,0.443944853,DB0078710012174_,0.81205493,0.099817885,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,acyclovir,DB00787
,103325,DB09020,10012174,43,1911,50,1554,0.091908073,0.699419402,0.45154493,1.079323612,0.198268596,DB0902010012174_,1.618132623,-0.357504714,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,bisacodyl,DB09020
,103327,DB00727,10037660,62,3781,73,4100,0.664592667,0.921008479,0.643783908,1.314029687,0.795845753,DB0072710037660_,0.22834989,-0.082286036,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,103329,DB01042,10037660,22,968,50,1278,0.039206168,0.581039043,0.332628544,0.985111039,0.104031306,DB0104210037660_,2.263063403,-0.542937324,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,melphalan,DB01042
,103335,DB00480,10023681,98,67330,64,67598,0.007426623,1.537331468,1.110400679,2.141201443,0.02807144,DB0048010023681_,3.573002606,0.4300481,NA,10023681,Lactose intolerance,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,103344,DB00335,10043607,64,8402,51,5414,0.291430983,0.808642338,0.550032698,1.194131316,0.456906348,DB0033510043607_,0.783276836,-0.212398563,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,atenolol,DB00335
,103345,DB00254,10051055,21,5914,33,3355,0.000293144,0.361048678,0.198196451,0.644135069,0.001980539,DB0025410051055_,6.224386074,-1.018742488,male,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,doxycycline,DB00254
,103349,DB00108,10028810,108,10086,25,3270,0.155023277,1.400539205,0.898027301,2.263379222,0.290817318,DB0010810028810_,1.235059983,0.336857309,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,natalizumab,DB00108
,103362,DB06724,10020772,144,7785,44,3875,0.004763393,1.628945325,1.152053856,2.343542995,0.01967407,DB0672410020772_,3.928453749,0.487932765,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,calcium carbonate,DB06724
,103364,DB06724,10021114,47,7882,7,3912,0.001200434,3.332178562,1.494872881,8.746146762,0.006410689,DB0672410021114_,5.049788535,1.203626313,female,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,calcium carbonate,DB06724
,103367,DB06724,10031161,80,7849,8,3911,1.62558253162165e-07,4.982877349,2.407217079,11.94808291,2.81942836315902e-06,DB0672410031161_,12.7789764,1.606007505,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,103368,DB00153,10038435,74,7349,37,3402,0.683110663,0.925848854,0.614458942,1.416582412,0.808418727,DB0015310038435_,0.212675128,-0.077044282,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,ergocalciferol,DB00153
,103381,DB00390,10002855,57,4088,17,3284,0.000146443,2.693117053,1.540829767,4.948256252,0.001103884,DB0039010002855_,6.808920205,0.990699278,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,digoxin,DB00390
,103382,DB00413,10003549,61,2138,42,1165,0.251517221,0.79147718,0.521922772,1.21013973,0.41151368,DB0041310003549_,0.887913014,-0.233854231,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pramipexole,DB00413
,103387,DB00413,10021097,26,2173,30,1177,0.006843157,0.469530611,0.265357824,0.825731484,0.026335634,DB0041310021097_,3.636832337,-0.756021783,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,pramipexole,DB00413
,103388,DB00390,10037844,80,4065,62,3239,0.932085928,1.028131064,0.726217161,1.461404229,0.972972376,DB0039010037844_,0.027399587,0.027742653,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,digoxin,DB00390
,103395,DB00012,10025482,39,1607,33,1280,0.811233691,0.941375969,0.573251734,1.554112493,0.898541046,DB0001210025482_,0.106982891,-0.060412677,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,darbepoetin alfa,DB00012
,103398,DB01050,10041349,201,17907,98,9273,0.667797911,1.062106535,0.829026026,1.368256756,0.798193265,DB0105010041349_,0.225404524,0.060254233,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,103399,DB00060,10038435,40,9468,12,2453,0.609359564,0.863595897,0.443355874,1.811243664,0.75180301,DB0006010038435_,0.285280944,-0.146650331,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,interferon beta-1a,DB00060
,103425,DB01067,10037660,55,4306,78,4745,0.162279707,0.777039113,0.538612112,1.11438874,0.300425589,DB0106710037660_,1.202555179,-0.252264592,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,103441,DB00451,10000891,86,47185,46,15373,0.008283398,0.609115102,0.420816199,0.891808854,0.030618635,DB0045110000891_,3.486146473,-0.495748027,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,103445,DB00381,10015150,215,29145,119,22768,0.002760944,1.411396081,1.12223273,1.782104849,0.012628803,DB0038110015150_,4.371775123,0.344579343,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,103449,DB00489,10025482,32,1051,27,1107,0.430196398,1.248206689,0.718960951,2.181857703,0.598655919,DB0048910025482_,0.513068272,0.221707872,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sotalol,DB00489
,103451,DB00381,10033546,30,29330,22,22865,0.889309627,1.063072223,0.592850611,1.934672396,0.953995558,DB0038110033546_,0.047096264,0.061163039,NA,10033546,Pallor,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,103454,DB00381,10046274,39,29321,39,22848,0.304224188,0.779245969,0.486744736,1.247480054,0.470869,DB0038110046274_,0.753175356,-0.249428533,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,103482,DB00531,10048294,45,7207,48,6468,0.407126141,0.841381698,0.546752675,1.292713864,0.576687986,DB0053110048294_,0.550453911,-0.17270986,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,cyclophosphamide,DB00531
,103490,DB00635,10049088,80,32973,27,23767,0.000385073,2.135666475,1.364901091,3.438389652,0.002485057,DB0063510049088_,5.997459874,0.758778764,NA,10049088,Osteopenia,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,103493,DB00028,10060795,33,13425,17,5598,0.534222614,0.80947592,0.437680149,1.550815117,0.690843855,DB0002810060795_,0.36984145,-0.211368253,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,human immunoglobulin g,DB00028
,103502,DB00028,10010774,46,13412,20,5595,0.892620764,0.95947688,0.555726263,1.713920402,0.955295567,DB0002810010774_,0.045734492,-0.04136706,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,human immunoglobulin g,DB00028
,103508,DB00695,10016454,69,27980,30,20498,0.018719865,1.684945235,1.082282818,2.681011823,0.058655885,DB0069510016454_,2.836067372,0.521733062,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,103509,DB00761,10016454,34,15273,22,8603,0.676217349,0.87053623,0.49423375,1.563399618,0.803815626,DB0076110016454_,0.218385357,-0.138645901,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,103511,DB00722,10016970,37,25366,17,26015,0.00599393,2.232132409,1.225468153,4.228991412,0.023643799,DB0072210016970_,3.744654381,0.802957366,NA,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,103513,DB00722,10018627,45,25358,72,25960,0.020366804,0.639846296,0.430629102,0.941842026,0.062690024,DB0072210018627_,2.769552958,-0.446527294,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,103515,DB00761,10020646,102,15205,84,8541,0.011227132,0.682132814,0.505339441,0.922802103,0.039058324,DB0076110020646_,3.242699254,-0.382530898,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,103517,DB00761,10022972,30,15277,21,8604,0.466851564,0.804591342,0.445233933,1.479542235,0.633432919,DB0076110022972_,0.456601175,-0.21742078,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,potassium chloride,DB00761
,103531,DB00761,10031161,57,15250,7,8618,9.92956013360094e-06,4.601108178,2.093459946,11.96403886,0.000107918,DB0076110031161_,9.134143457,1.526297183,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,103533,DB00695,10031282,54,27995,13,20515,9.94990345637997e-05,3.043865596,1.638791776,6.081594743,0.000793616,DB0069510031282_,7.13891097,1.113128285,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,103534,DB00722,10031282,49,25354,12,26020,9.75960588547831e-07,4.190183677,2.195976111,8.657827904,1.400279698143e-05,DB0072210031282_,11.17625346,1.43274457,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,103536,DB00028,10038435,38,13420,36,5579,0.000494205,0.438834142,0.270466738,0.713252286,0.003061916,DB0002810038435_,5.78871445,-0.823633747,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,human immunoglobulin g,DB00028
,103557,DB00695,10049088,34,28015,21,20507,0.586737798,1.185125657,0.668095668,2.149580807,0.733875946,DB0069510049088_,0.309415275,0.169848808,NA,10049088,Osteopenia,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,103587,DB06769,10011906,22,645,37,1019,0.892222712,0.939393421,0.522770016,1.651873688,0.955096007,DB0676910011906_,0.045943412,-0.062520909,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,bendamustine,DB06769
,103606,DB00646,10074170,41,3412,23,1977,1,1.032884659,0.603343807,1.808814736,1,DB0064610074170_,0,0.032355528,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,nystatin,DB00646
,103619,DB00158,10013946,98,16717,24,8080,0.001868458,1.97359217,1.251500046,3.228553371,0.009203113,DB0015810013946_,4.688213428,0.679855319,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,103624,DB00169,10017626,64,38627,27,18148,0.735887283,1.11365767,0.699740584,1.817428403,0.847406972,DB0016910017626_,0.165574213,0.107649796,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,cholecalciferol,DB00169
,103627,DB00169,10020096,53,38638,14,18161,0.065419129,1.779381073,0.97296569,3.473604089,0.153159584,DB0016910020096_,1.876274865,0.576265592,NA,10020096,Hip arthroplasty,10042613,Surgical and medical procedures,Surg,cholecalciferol,DB00169
,103659,DB00158,10046543,30,16785,21,8083,0.230509389,0.687939295,0.380704454,1.265092123,0.386522872,DB0015810046543_,0.950564235,-0.374054679,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,folic acid,DB00158
,103683,DB00203,10052915,82,13796,35,8903,0.04573709,1.511893682,1.005167994,2.317014424,0.116973915,DB0020310052915_,2.145804316,0.413362959,NA,10052915,Catheter placement,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,103684,DB01240,10052915,161,5590,54,1522,0.205993027,0.811798157,0.589645235,1.132407853,0.35647684,DB0124010052915_,1.031486006,-0.208503544,NA,10052915,Catheter placement,10042613,Surgical and medical procedures,Surg,epoprostenol,DB01240
,103690,DB00203,10008629,40,13838,24,8914,0.898088324,1.07362072,0.631104639,1.863226924,0.956338178,DB0020310008629_,0.044643686,0.071036786,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,sildenafil,DB00203
,103691,DB00331,10002948,34,24912,21,20731,0.343018951,1.347310917,0.759500736,2.44368673,0.512345331,DB0033110002948_,0.668756407,0.298110693,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,metformin,DB00331
,103692,DB00722,10002948,43,25360,38,25994,0.507475154,1.159863974,0.731881781,1.844683142,0.668120151,DB0072210002948_,0.403287255,0.148302735,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,103702,DB00169,10022998,80,38611,58,18117,0.01338881,0.647195673,0.455620583,0.924227431,0.044926132,DB0016910022998_,3.102735646,-0.4351066,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,103705,DB01373,10022998,40,22680,17,7364,0.356155771,0.763987091,0.423089882,1.438105068,0.5258414,DB0137310022998_,0.642755632,-0.269204387,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,calcium,DB01373
,103707,DB00169,10039897,38,38653,17,18158,1,1.050071704,0.578360401,1.984567634,1,DB0016910039897_,0,0.048858451,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,103711,DB01202,10039897,36,6678,20,5698,0.139626703,1.535793451,0.864444844,2.803355008,0.269301154,DB0120210039897_,1.311924994,0.429047153,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,103714,DB01202,10061822,48,6666,39,5679,0.914127418,1.048542513,0.671785108,1.645731343,0.961536643,DB0120210061822_,0.039222604,0.047401117,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,103718,DB00060,10009033,43,9465,10,2455,0.865713641,1.11530932,0.550878337,2.492688605,0.939001095,DB0006010009033_,0.062938633,0.109131784,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,interferon beta-1a,DB00060
,103719,DB08906,10009033,52,2141,66,1092,1.56481398023363e-06,0.401967572,0.271885921,0.591647616,2.13890460064695e-05,DB0890610009033_,10.75263164,-0.91138386,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone furoate,DB08906
,103720,DB08906,10025482,94,2099,20,1138,5.36775619760792e-05,2.54756517,1.550047796,4.383689649,0.000468898,DB0890610025482_,7.665124847,0.935138068,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,fluticasone furoate,DB08906
,103724,DB08906,10037660,40,2153,28,1130,0.248557033,0.749876855,0.448554385,1.269293611,0.407950148,DB0890610037660_,0.896610299,-0.287846279,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,fluticasone furoate,DB08906
,103726,DB00956,10000081,75,5739,29,3438,0.052268978,1.549221456,0.994609475,2.47273261,0.129282968,DB0095610000081_,2.045751729,0.437752518,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,hydrocodone,DB00956
,103727,DB00395,10002855,52,2132,11,725,0.18640461,1.607232731,0.822895808,3.435226374,0.331967811,DB0039510002855_,1.10271727,0.4745139,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,carisoprodol,DB00395
,103731,DB00395,10012378,64,2120,13,723,0.109440129,1.678768387,0.90875739,3.342722854,0.22524734,DB0039510012378_,1.490556191,0.518060422,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,carisoprodol,DB00395
,103746,DB05679,10008190,32,6899,27,4882,0.510282584,0.83869966,0.486080102,1.457181116,0.670754092,DB0567910008190_,0.399352689,-0.17590261,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,ustekinumab,DB05679
,103749,DB00381,10061599,49,29311,28,22859,0.206895117,1.364776682,0.840646609,2.256049155,0.35754831,DB0038110061599_,1.028484792,0.310990812,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,103752,DB00364,10012735,214,2536,88,1312,0.087793669,1.257995702,0.967802791,1.646282397,0.191498826,DB0036410012735_,1.652873603,0.229519742,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sucralfate,DB00364
,103753,DB00983,10012735,87,3414,33,1707,0.202529506,1.318143517,0.869531142,2.041070659,0.351966154,DB0098310012735_,1.044220262,0.27622432,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,formoterol,DB00983
,103754,DB01029,10012735,83,1257,54,847,0.928387561,1.035684051,0.717877697,1.504410816,0.970169246,DB0102910012735_,0.030284743,0.035062127,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,irbesartan,DB01029
,103778,DB00727,10016256,264,3579,244,3929,0.06636665,1.187747671,0.988231386,1.427991273,0.154828027,DB0072710016256_,1.865440279,0.1720588,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,103779,DB00983,10016256,183,3318,38,1702,7.33575206303671e-08,2.469944351,1.724228132,3.619794803,1.36751945373702e-06,DB0098310016256_,13.50251208,0.90419562,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,formoterol,DB00983
,103781,DB11074,10016256,91,1169,60,808,0.797405368,1.048287721,0.738663147,1.496449043,0.890446532,DB1107410016256_,0.116032221,0.047158091,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dimethicone,DB11074
,103782,DB00231,10020772,50,3246,30,2109,0.817866775,1.082869227,0.67277986,1.770035979,0.902749624,DB0023110020772_,0.102310035,0.07961421,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,temazepam,DB00231
,103784,DB00364,10020772,38,2712,23,1377,0.498380368,0.838928151,0.484912999,1.481319403,0.660264011,DB0036410020772_,0.415115508,-0.175630213,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,sucralfate,DB00364
,103785,DB00398,10020772,39,688,54,1484,0.041404213,1.557512607,0.994070727,2.421233681,0.108554162,DB0039810020772_,2.220506045,0.443090066,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,sorafenib,DB00398
,103786,DB00512,10020772,48,4689,45,5053,0.532512591,1.149452914,0.747695703,1.769916659,0.68932523,DB0051210020772_,0.372042087,0.139286102,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,vancomycin,DB00512
,103788,DB00983,10020772,35,3466,16,1724,0.881618081,1.08805015,0.584649062,2.111587706,0.950483399,DB0098310020772_,0.050784582,0.084387241,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,formoterol,DB00983
,103789,DB00997,10020772,75,5256,40,3474,0.292574915,1.239255038,0.831286257,1.871998883,0.458166913,DB0099710020772_,0.780521722,0.214510423,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,doxorubicin,DB00997
,103811,DB00213,10042128,104,18791,43,13378,0.002437958,1.721860506,1.195088322,2.518926047,0.011433976,DB0021310042128_,4.471165993,0.543405396,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,103824,DB00364,10047895,84,2666,41,1359,0.848364544,1.044362243,0.706249215,1.565753237,0.92428343,DB0036410047895_,0.078736512,0.043406405,NA,10047895,Weight decreased,10022891,Investigations,Inv,sucralfate,DB00364
,103825,DB00512,10047895,37,4700,38,5060,0.907787485,1.048278852,0.647092764,1.696791309,0.958771936,DB0051210047895_,0.042102046,0.047149631,NA,10047895,Weight decreased,10022891,Investigations,Inv,vancomycin,DB00512
,103826,DB00727,10047895,83,3760,95,4078,0.761726,0.947566067,0.694794011,1.290233023,0.867966655,DB0072710047895_,0.141601982,-0.053858617,NA,10047895,Weight decreased,10022891,Investigations,Inv,nitroglycerin,DB00727
,103827,DB00972,10047895,38,2466,24,1155,0.272617417,0.74162485,0.431197951,1.298996559,0.435544773,DB0097210047895_,0.831157679,-0.298911757,NA,10047895,Weight decreased,10022891,Investigations,Inv,azelastine,DB00972
,103828,DB01029,10047895,31,1309,23,878,0.77912124,0.904084641,0.50650965,1.635440966,0.879672513,DB0102910047895_,0.128205585,-0.100832294,NA,10047895,Weight decreased,10022891,Investigations,Inv,irbesartan,DB01029
,103830,DB11074,10047895,34,1226,23,845,1,1.0188587,0.578238314,1.825454548,1,DB1107410047895_,0,0.018683079,NA,10047895,Weight decreased,10022891,Investigations,Inv,dimethicone,DB11074
,103831,DB00480,10017853,37,67391,25,67637,0.129201941,1.485390471,0.870449067,2.574602813,0.254473269,DB0048010017853_,1.368559481,0.395677681,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,103846,DB00722,10039674,41,25362,32,26000,0.291773163,1.313469418,0.806873115,2.155532845,0.457206032,DB0072210039674_,0.782621154,0.272672047,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,103859,DB00047,10018627,23,9262,30,8488,0.216981572,0.702616925,0.38942784,1.252107026,0.369867744,DB0004710018627_,0.994609785,-0.352943451,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,insulin glargine,DB00047
,103860,DB00158,10018627,30,16785,26,8078,0.031681062,0.555287838,0.317175949,0.978218548,0.088398597,DB0015810018627_,2.425899184,-0.588268673,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,folic acid,DB00158
,103863,DB00480,10018627,128,67300,209,67453,1.18189896621797e-05,0.613838376,0.488584426,0.768734412,0.000125647,DB0048010018627_,8.982034377,-0.488023617,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,103865,DB00904,10018627,27,23042,31,14425,0.021726956,0.545281719,0.312947776,0.94448939,0.065999758,DB0090410018627_,2.71810421,-0.606452702,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,103906,DB00222,10035664,108,3098,118,3010,0.416363502,0.889273069,0.675147032,1.170324541,0.585606905,DB0022210035664_,0.535106526,-0.117350927,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,glimepiride,DB00222
,103907,DB01241,10035664,31,912,40,1031,0.629275067,0.876181537,0.525200739,1.449610401,0.768324746,DB0124110035664_,0.263542789,-0.132181976,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,gemfibrozil,DB01241
,103909,DB00046,10038695,55,5404,59,4633,0.257148733,0.799224945,0.542065414,1.176738623,0.418016748,DB0004610038695_,0.872233781,-0.224112839,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin lispro,DB00046
,103910,DB00047,10038695,70,9215,61,8457,0.792783688,1.053160153,0.735397997,1.511715568,0.887662424,DB0004710038695_,0.119163761,0.051795313,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,103912,DB00646,10038695,62,3391,48,1952,0.134151247,0.743598813,0.499686842,1.112322958,0.261517078,DB0064610038695_,1.341255691,-0.29625362,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nystatin,DB00646
,103913,DB01076,10038695,189,25558,202,25381,0.477617311,0.929192717,0.757354786,1.139586621,0.642929916,DB0107610038695_,0.441719556,-0.073439116,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,103915,DB09020,10038695,30,1924,29,1575,0.598107999,0.846876862,0.488859561,1.469169907,0.742999711,DB0902010038695_,0.297059623,-0.166199976,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bisacodyl,DB09020
,103927,DB00904,10045170,24,23045,31,14425,0.008086992,0.484607098,0.27204748,0.853465071,0.03005244,DB0090410045170_,3.504811433,-0.724416824,NA,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,103936,DB00230,10001488,19,19655,34,8617,5.53462132798625e-07,0.244983521,0.131945489,0.442210276,8.49503775802152e-06,DB0023010001488_,11.67602836,-1.406564334,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,103938,DB00230,10002368,47,19627,28,8623,0.210081242,0.73746342,0.452023668,1.223812183,0.361256449,DB0023010002368_,1.018167187,-0.304538793,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,103940,DB00482,10016322,136,8123,39,3032,0.170028612,1.301577224,0.903311521,1.914008439,0.310916357,DB0048210016322_,1.168231353,0.263576778,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,103946,DB00656,10048959,161,11852,79,6540,0.415868767,1.124575479,0.852361846,1.493977032,0.585051945,DB0065610048959_,0.536054641,0.117405612,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,103947,DB00921,10048959,57,5788,24,4879,0.003527776,2.001849704,1.22045778,3.378316054,0.015419904,DB0092110048959_,4.172096118,0.694071605,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,103961,DB08932,10062352,100,19343,20,6577,0.027188431,1.699988969,1.043411304,2.904354089,0.078429315,DB0893210062352_,2.545557511,0.530621762,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,103977,DB00455,10061818,96,9305,51,5067,0.930996462,1.025026754,0.721122754,1.471914094,0.972103284,DB0045510061818_,0.028293221,0.024718713,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,103979,DB00028,10058080,50,13408,15,5600,0.279095172,1.39212461,0.768462873,2.671807882,0.442936008,DB0002810058080_,0.814329972,0.330831077,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,103980,DB00186,10058080,42,16859,22,9986,0.698906197,1.130817793,0.659443342,1.990229781,0.818987281,DB0018610058080_,0.199686725,0.122941082,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,lorazepam,DB00186
,103981,DB00404,10058080,50,19842,21,9841,0.613945604,1.180854073,0.696002578,2.071099714,0.755564886,DB0040410058080_,0.280289617,0.166237967,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,alprazolam,DB00404
,103983,DB00668,10058080,49,10042,12,4291,0.092301061,1.74477047,0.913474372,3.607716618,0.198895998,DB0066810058080_,1.614973213,0.556623011,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,epinephrine,DB00668
,103984,DB01075,10058080,63,19885,30,11067,0.517132809,1.168729659,0.744821499,1.871525068,0.676782389,DB0107510058080_,0.390405492,0.155917397,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,103987,DB00795,10000059,143,4426,25,1478,0.001985179,1.910016055,1.236743458,3.062643764,0.009666703,DB0079510000059_,4.639068008,0.647111648,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,sulfasalazine,DB00795
,103991,DB00795,10037087,78,4491,26,1477,0.909338078,0.986641798,0.623059055,1.6091944,0.959243559,DB0079510037087_,0.041610265,-0.013448226,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,sulfasalazine,DB00795
,103992,DB00795,10046735,63,4506,13,1490,0.14092938,1.602309503,0.869818273,3.183353563,0.271190655,DB0079510046735_,1.304933182,0.471446028,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,sulfasalazine,DB00795
,103994,DB00795,10048959,82,4487,20,1483,0.248493494,1.35500856,0.819825982,2.341550251,0.407884065,DB0079510048959_,0.896772298,0.303807771,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,103997,DB00563,10015967,48,46598,11,15337,0.36450056,1.43618763,0.73526685,3.067679997,0.534143293,DB0056310015967_,0.627091137,0.361992124,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,methotrexate,DB00563
,104000,DB08868,10019465,73,9129,13,2498,0.186441863,1.536486802,0.843216213,3.027521586,0.332009375,DB0886810019465_,1.102592073,0.429498513,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,104004,DB00668,10021789,127,9964,45,4258,0.314820582,1.206014652,0.850349024,1.737851043,0.482398215,DB0066810021789_,0.728985333,0.187321247,NA,10021789,Infection,10021881,Infections and infestations,Infec,epinephrine,DB00668
,104005,DB09153,10021789,133,7666,83,5616,0.267058547,1.173872541,0.883724742,1.566916561,0.429339157,DB0915310021789_,0.845508096,0.160308147,NA,10021789,Infection,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,104016,DB01097,10003549,70,6195,25,1478,0.089377658,0.66806231,0.416084587,1.105118017,0.194260698,DB0109710003549_,1.63855422,-0.403373832,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,104018,DB00924,10012735,521,9641,169,4082,0.003129854,1.305203002,1.090835523,1.568078646,0.014005486,DB0092410012735_,4.268306166,0.266358586,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,104019,DB06218,10012735,42,1652,22,1414,0.075396988,1.63379977,0.948131024,2.888559785,0.170472959,DB0621810012735_,1.769178592,0.490908449,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lacosamide,DB06218
,104020,DB06218,10028813,61,1633,46,1390,0.555391165,1.128703041,0.751754207,1.704741264,0.708750207,DB0621810028813_,0.344252133,0.121069222,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lacosamide,DB06218
,104022,DB00983,10016322,53,3448,19,1721,0.256893869,1.392226969,0.807763729,2.498498777,0.417785327,DB0098310016322_,0.87278755,0.330904601,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,formoterol,DB00983
,104034,DB00005,10059866,49,128033,28,42391,0.024528836,0.579417743,0.35698422,0.95756282,0.072448691,DB0000510059866_,2.624876681,-0.545731571,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,104035,DB00620,10015150,56,4772,40,3092,0.67457736,0.907137472,0.592248498,1.400780451,0.802671507,DB0062010015150_,0.219809731,-0.097461272,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,triamcinolone,DB00620
,104038,DB00620,10040844,24,4804,34,3098,0.004179486,0.455250019,0.257753692,0.792356861,0.017700442,DB0062010040844_,4.034165678,-0.786908518,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,triamcinolone,DB00620
,104042,DB00213,10039203,39,18856,22,13399,0.436287335,1.259683696,0.728265623,2.231791666,0.604842436,DB0021310039203_,0.502787291,0.230860654,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,104043,DB00656,10039203,43,11970,20,6599,0.598895446,1.185248731,0.681663125,2.12878792,0.7436826,DB0065610039203_,0.296140948,0.169952652,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,104046,DB00264,10001052,49,29558,37,24855,0.665540868,1.113580124,0.711671556,1.755981568,0.796538571,DB0026410001052_,0.227479725,0.107580162,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,104048,DB01118,10001052,15,3048,51,4658,0.005123589,0.449518063,0.234305838,0.813914378,0.020862866,DB0111810001052_,3.869784429,-0.799579242,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,104059,DB00656,10044565,185,11828,93,6526,0.487862526,1.097556212,0.849299677,1.42638208,0.651528496,DB0065610044565_,0.428434145,0.093086083,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,104060,DB08815,10044565,42,1412,26,677,0.357286149,0.774637466,0.4595695,1.327928499,0.526992308,DB0881510044565_,0.640569327,-0.255360145,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,lurasidone,DB08815
,104062,DB08815,10047899,54,1400,27,676,0.904038024,0.965753742,0.591685866,1.609790079,0.957450283,DB0881510047899_,0.043481484,-0.034846403,NA,10047899,Weight increased,10022891,Investigations,Inv,lurasidone,DB08815
,104078,DB00761,10038063,68,15239,42,8583,0.6906727,0.911894985,0.611165078,1.374738524,0.81342079,DB0076110038063_,0.206506726,-0.092230444,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,104081,DB09072,10040753,115,6356,29,2506,0.031556771,1.563467858,1.029805525,2.444301504,0.088135504,DB0907210040753_,2.428879827,0.44690634,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,sodium oxybate,DB09072
,104085,DB01254,10000059,33,3434,35,3113,0.543421864,0.854743291,0.513452202,1.41998797,0.698629381,DB0125410000059_,0.358634891,-0.1569541,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,dasatinib,DB01254
,104093,DB01104,10029354,90,15373,41,7245,0.925273582,1.03449052,0.70673955,1.537175647,0.967973417,DB0110410029354_,0.032550654,0.033909054,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,sertraline,DB01104
,104094,DB00688,10009887,53,6437,45,5333,0.919133937,0.975774115,0.642251788,1.488120591,0.964291834,DB0068810009887_,0.036361298,-0.024524159,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,mycophenolate mofetil,DB00688
,104095,DB00688,10013700,45,6445,14,5364,0.00088961,2.674877815,1.44004317,5.282158586,0.005004471,DB0068810013700_,5.297423623,0.983903703,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,mycophenolate mofetil,DB00688
,104152,DB01234,10074171,31,31594,37,32851,0.628015258,0.871174476,0.52254939,1.443458967,0.767336353,DB0123410074171_,0.264830043,-0.137913006,NA,10074171,Aspergillus infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,104161,DB00982,10013573,52,3312,17,2084,0.017793981,1.924481223,1.09149153,3.560148199,0.056378351,DB0098210013573_,2.87567005,0.654656437,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,isotretinoin,DB00982
,104165,DB06285,10003549,191,8659,21,1085,0.658668727,1.139677682,0.720752831,1.892094504,0.791554443,DB0628510003549_,0.233756618,0.130745487,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,104166,DB06285,10013573,500,8350,40,1066,0.003828214,1.595741151,1.146976689,2.275318489,0.016463448,DB0628510013573_,4.106612608,0.4673383,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,teriparatide,DB06285
,104168,DB06285,10025482,217,8633,17,1089,0.058098903,1.610123336,0.977708127,2.826377418,0.139866252,DB0628510025482_,1.967068653,0.476310782,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,104174,DB00950,10003658,34,4684,23,2033,0.111326787,0.641655969,0.366053718,1.143952905,0.22805008,DB0095010003658_,1.478190025,-0.443702993,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,fexofenadine,DB00950
,104180,DB00264,10010071,57,29550,52,24840,0.70076186,0.921439461,0.621303013,1.369168452,0.820158314,DB0026410010071_,0.198257892,-0.0818182,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,104213,DB00661,10003239,82,3446,20,1575,0.01252499,1.873710355,1.133497257,3.238411293,0.04260912,DB0066110003239_,3.155686961,0.627920612,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,verapamil,DB00661
,104214,DB01394,10003239,66,1374,57,1946,0.008893154,1.639647107,1.124732534,2.396640046,0.032412166,DB0139410003239_,3.429221438,0.49448104,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,colchicine,DB01394
,104218,DB01217,10012378,48,2706,6,262,0.473871287,0.774648132,0.326757272,2.236256984,0.639721978,DB0121710012378_,0.446721607,-0.255346376,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,anastrozole,DB01217
,104224,DB06724,10013911,48,7881,22,3897,0.89868659,1.078857812,0.637683839,1.879603134,0.95647837,DB0672410013911_,0.044497104,0.0759029,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,104229,DB00437,10028411,68,6853,75,11471,0.014934281,1.51754406,1.075133979,2.138921401,0.049147754,DB0043710028411_,3.012924137,0.417093278,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,allopurinol,DB00437
,104230,DB00575,10028411,41,5203,20,3809,0.152983116,1.500692957,0.857680875,2.708365748,0.288158595,DB0057510028411_,1.244244272,0.405926973,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,clonidine,DB00575
,104234,DB01394,10028411,42,1398,23,1980,0.00020287,2.585593606,1.511886754,4.52586043,0.001458346,DB0139410028411_,6.530452316,0.949955116,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,colchicine,DB01394
,104236,DB00661,10037660,42,3486,21,1574,0.683547353,0.903063339,0.520880835,1.610883018,0.808683417,DB0066110037660_,0.212347765,-0.101962585,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,verapamil,DB00661
,104238,DB01394,10037660,38,1402,36,1967,0.096541252,1.48073781,0.908601779,2.41748671,0.205597472,DB0139410037660_,1.581835042,0.392540484,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,colchicine,DB01394
,104247,DB00437,10061428,149,6772,234,11312,0.557861961,1.063631414,0.858273353,1.314821634,0.710901105,DB0043710061428_,0.341221952,0.061688915,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,allopurinol,DB00437
,104248,DB00661,10061428,41,3487,15,1580,0.562543694,1.238430222,0.668785959,2.416158942,0.714753401,DB0066110061428_,0.335817689,0.213844628,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,verapamil,DB00661
,104250,DB01394,10061428,29,1411,32,1971,0.362760327,1.265824928,0.735103753,2.171384586,0.532273931,DB0139410061428_,0.630597014,0.235724027,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,colchicine,DB01394
,104251,DB06724,10061428,170,7759,94,3825,0.389964993,0.891565506,0.68683513,1.163160281,0.559877094,DB0672410061428_,0.580037994,-0.114776366,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,calcium carbonate,DB06724
,104253,DB00374,10049438,159,17557,79,5645,0.002327072,0.647131884,0.490176912,0.860161139,0.011006226,DB0037410049438_,4.509294197,-0.435205165,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,104254,DB00682,10049438,87,19372,49,16315,0.024851356,1.495305722,1.041129621,2.169112548,0.073169186,DB0068210049438_,2.614980909,0.402330682,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,104255,DB00820,10049438,77,11838,44,5772,0.437014839,0.853287205,0.580843642,1.267247078,0.60559076,DB0082010049438_,0.501550834,-0.158659088,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,104256,DB08932,10049438,135,19308,56,6541,0.210478478,0.816669011,0.593043627,1.137582794,0.361773862,DB0893210049438_,1.016735952,-0.202521393,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,104257,DB01373,10003285,137,22583,37,7344,0.376591328,1.204108472,0.831235611,1.783334028,0.546421352,DB0137310003285_,0.604364893,0.185739436,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,104258,DB00722,10000381,25,25378,32,26000,0.428763171,0.800402936,0.454627255,1.394395362,0.5972939,DB0072210000381_,0.515345992,-0.222640009,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,104267,DB00983,10047899,37,3464,15,1725,0.556546549,1.22827108,0.655907352,2.416017981,0.70989596,DB0098310047899_,0.342636855,0.205607554,NA,10047899,Weight increased,10022891,Investigations,Inv,formoterol,DB00983
,104276,DB00635,10000269,41,33012,34,23760,0.55951654,0.867924225,0.537199036,1.410485763,0.712223589,DB0063510000269_,0.339363387,-0.141650867,NA,10000269,Abscess,10021881,Infections and infestations,Infec,prednisone,DB00635
,104282,DB00327,10007882,39,6099,36,4226,0.238890042,0.750673772,0.463997553,1.217471742,0.396603489,DB0032710007882_,0.924818265,-0.286784113,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,hydromorphone,DB00327
,104283,DB00787,10007882,89,16911,115,17133,0.091851517,0.784080035,0.587257781,1.04400261,0.19821166,DB0078710007882_,1.618419829,-0.243244178,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,acyclovir,DB00787
,104284,DB00281,10013950,63,11395,32,5639,0.913159893,0.974248289,0.626172072,1.542987203,0.961104948,DB0028110013950_,0.039671669,-0.026089091,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,104285,DB00327,10013950,49,6089,23,4239,0.148497704,1.483096975,0.884950984,2.554699217,0.28192576,DB0032710013950_,1.266111504,0.394132452,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,hydromorphone,DB00327
,104286,DB00512,10013950,18,4719,34,5064,0.052224548,0.568150547,0.30164331,1.036257782,0.129211574,DB0051210013950_,2.046304107,-0.565368848,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,vancomycin,DB00512
,104304,DB00327,10029354,43,6095,37,4225,0.361932871,0.805624068,0.506012788,1.288250478,0.531668232,DB0032710029354_,0.631735608,-0.216138062,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,hydromorphone,DB00327
,104306,DB01413,10029354,38,1182,60,1599,0.532827047,0.856823238,0.551145833,1.317727146,0.689630398,DB0141310029354_,0.37159948,-0.154523639,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,cefepime,DB01413
,104307,DB00186,10033433,47,16854,19,9989,0.16346644,1.466078843,0.843517232,2.64689623,0.302043189,DB0018610033433_,1.197185263,0.382591383,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,104310,DB00497,10033433,48,19219,15,16360,0.000344439,2.723799149,1.498755949,5.238354239,0.002265096,DB0049710033433_,6.090137973,1.002027652,female,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,104312,DB00761,10033433,106,15201,39,8586,0.023768761,1.535156267,1.053131437,2.278862468,0.070714418,DB0076110033433_,2.649105802,0.428632179,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,104317,DB00878,10037660,51,1135,40,880,1,0.988549804,0.634206346,1.550058569,1,DB0087810037660_,0,-0.011516254,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,chlorhexidine,DB00878
,104324,DB00787,10044055,35,16965,21,17227,0.06100939,1.692369245,0.957650512,3.061048861,0.145309154,DB0078710044055_,1.928891713,0.526129467,NA,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,104345,DB00761,10063743,52,15255,25,8600,0.553955295,1.172569389,0.714024603,1.973546776,0.707500543,DB0076110063743_,0.346016882,0.1591974,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,104346,DB00787,10063743,47,16953,32,17216,0.090845133,1.491509893,0.931366251,2.41652298,0.196582703,DB0078710063743_,1.626672055,0.399788958,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,acyclovir,DB00787
,104368,DB01137,10003553,60,7712,7,5586,2.76611488156551e-08,6.207753472,2.832011619,16.10955684,5.61663419559284e-07,DB0113710003553_,14.39236306,1.825799071,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,104370,DB00332,10008469,51,2633,15,1641,0.010161469,2.118695914,1.168078524,4.071300032,0.036020797,DB0033210008469_,3.323658809,0.750800765,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,ipratropium,DB00332
,104383,DB00471,10024570,44,14145,6,5459,0.010881213,2.830293884,1.200619591,8.13122198,0.038084246,DB0047110024570_,3.267954567,1.040380552,female,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,104405,DB00332,10040753,88,2596,14,1642,7.08703332130574e-08,3.974790101,2.238261874,7.593851955,1.32538364176821e-06,DB0033210040753_,13.5338086,1.379971942,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,ipratropium,DB00332
,104406,DB01112,10040753,46,1099,15,564,0.166797129,1.573411807,0.853668856,3.061851285,0.306538195,DB0111210040753_,1.182412916,0.453246387,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,cefuroxime,DB01112
,104407,DB01137,10040753,183,7589,55,5538,1.07735161692792e-09,2.427869911,1.783212173,3.351667241,2.97147820051944e-08,DB0113710040753_,17.3316212,0.887014293,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,levofloxacin,DB01137
,104408,DB06282,10040753,87,1453,16,517,0.014846512,1.934222205,1.113811785,3.566828131,0.048908455,DB0628210040753_,3.017804994,0.659705284,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,levocetirizine,DB06282
,104410,DB00471,10042682,67,14122,19,5446,0.277811026,1.359831855,0.806220949,2.399769872,0.441477755,DB0047110042682_,0.817627644,0.307361056,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,104414,DB00254,10046735,91,5844,30,3358,0.007583077,1.742876619,1.139529997,2.734670124,0.028537646,DB0025410046735_,3.556531141,0.555536977,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,doxycycline,DB00254
,104416,DB06282,10046735,44,1496,7,526,0.051118623,2.209438632,0.979208711,5.849419391,0.127131517,DB0628210046735_,2.062533159,0.79273847,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,levocetirizine,DB06282
,104417,DB00254,10047924,48,5887,12,3376,0.007050569,2.29368818,1.198151476,4.750177999,0.026946449,DB0025410047924_,3.613903735,0.830161081,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxycycline,DB00254
,104418,DB00332,10047924,38,2646,22,1634,0.89384855,1.066645114,0.61247237,1.900542859,0.95581177,DB0033210047924_,0.045194278,0.064518315,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipratropium,DB00332
,104420,DB01137,10047924,42,7730,28,5565,0.808702454,1.079894227,0.652900464,1.811485766,0.896808395,DB0113710047924_,0.108913046,0.076863099,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,104433,DB00879,10012378,23,1754,55,3657,0.627697435,0.871915663,0.509619459,1.44796367,0.767039846,DB0087910012378_,0.265216529,-0.137062577,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,emtricitabine,DB00879
,104438,DB01156,10024264,93,13529,49,6279,0.470218795,0.880882317,0.615888121,1.273544884,0.63647464,DB0115610024264_,0.451810705,-0.126831241,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,104445,DB00482,10008190,55,8204,21,3050,0.897460143,0.973684272,0.578236627,1.698119454,0.956338178,DB0048210008190_,0.044643686,-0.026668184,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,104449,DB00421,10020937,86,8817,25,5227,0.0010938,2.039247336,1.291517408,3.32780637,0.005929165,DB0042110020937_,5.127871808,0.712580787,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,104451,DB06413,10020937,40,1516,13,661,0.449317853,1.341473049,0.697238432,2.752125601,0.616904059,DB0641310020937_,0.483041762,0.2937683,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,armodafinil,DB06413
,104455,DB00421,10022086,50,8853,10,5242,0.000711888,2.960380014,1.482168409,6.552686831,0.004149456,DB0042110022086_,5.48477792,1.085317643,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,104459,DB00787,10033425,233,16767,133,17115,6.91840063756397e-08,1.788197766,1.437342534,2.232207007,1.29707675291276e-06,DB0078710033425_,13.55539748,0.581208278,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,104462,DB00316,10061016,48,65426,27,36926,1,1.003365958,0.613507201,1.672626192,1,DB0031610061016_,0,0.003360306,NA,10061016,Blood test abnormal,10022891,Investigations,Inv,acetaminophen,DB00316
,104469,DB00787,10061016,35,16965,46,17202,0.266863933,0.77150671,0.482202354,1.224632952,0.429088147,DB0078710061016_,0.84609291,-0.259409911,NA,10061016,Blood test abnormal,10022891,Investigations,Inv,acyclovir,DB00787
,104473,DB00169,10035226,215,38476,222,17953,3.74060434180523e-16,0.451889379,0.372534935,0.548045954,2.62191426998268e-14,DB0016910035226_,31.27228661,-0.794317867,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cholecalciferol,DB00169
,104509,DB08908,10040047,72,10601,37,3242,0.012409682,0.595135386,0.394158222,0.912119284,0.042274299,DB0890810040047_,3.163575963,-0.518966359,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,dimethyl fumarate,DB08908
,104510,DB00619,10016173,38,2861,23,2471,0.197595939,1.426860699,0.825957379,2.515966845,0.346057852,DB0061910016173_,1.061149317,0.355476715,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,imatinib,DB00619
,104516,DB00374,10015090,301,17415,83,5641,0.208708299,1.174672643,0.916535355,1.519341392,0.359778177,DB0037410015090_,1.022267613,0.160989507,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,104525,DB00688,10011224,129,6361,88,5290,0.168707268,1.219073255,0.92010036,1.621383222,0.309097726,DB0068810011224_,1.174097787,0.198090943,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolate mofetil,DB00688
,104526,DB00864,10011224,83,6786,109,8283,0.661581235,0.929433532,0.688715833,1.25045427,0.793595562,DB0086410011224_,0.231181315,-0.073179983,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tacrolimus,DB00864
,104528,DB00635,10017888,43,33010,25,23769,0.460923338,1.23848869,0.739291308,2.116514057,0.628243923,DB0063510017888_,0.464826775,0.213891838,NA,10017888,Gastroenteritis,10021881,Infections and infestations,Infec,prednisone,DB00635
,104534,DB00264,10038776,43,29564,33,24859,0.730585759,1.095691744,0.679769137,1.780650946,0.843292426,DB0026410038776_,0.170441494,0.091385893,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,104540,DB00635,10058854,100,32953,106,23688,0.005721575,0.678170345,0.510506954,0.900279654,0.022793512,DB0063510058854_,3.781279334,-0.388356776,NA,10058854,Cytomegalovirus viraemia,10021881,Infections and infestations,Infec,prednisone,DB00635
,104541,DB00864,10058854,105,6764,124,8268,0.840944686,1.035069615,0.788781428,1.356118927,0.918770126,DB0086410058854_,0.084719323,0.034468685,NA,10058854,Cytomegalovirus viraemia,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,104563,DB00136,10011906,75,2017,97,1585,0.001630832,0.607685084,0.440138631,0.836294406,0.008223773,DB0013610011906_,4.800726188,-0.498098485,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,calcitriol,DB00136
,104564,DB00905,10011906,40,2678,34,891,0.000118092,0.391543864,0.240026402,0.642011995,0.000919718,DB0090510011906_,6.991443752,-0.937657729,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,bimatoprost,DB00905
,104566,DB00136,10054112,29,2063,35,1647,0.127376247,0.661573933,0.388295396,1.119322399,0.251924369,DB0013610054112_,1.378626359,-0.413133536,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,calcitriol,DB00136
,104567,DB00316,10054112,500,64974,289,36664,0.765958021,0.976261498,0.842441468,1.133035353,0.870989683,DB0031610054112_,0.138125147,-0.0240248,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,104568,DB00641,10054112,106,14018,75,12400,0.155533431,1.250190157,0.920414389,1.705330816,0.291497124,DB0064110054112_,1.23272514,0.223295665,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,simvastatin,DB00641
,104569,DB00678,10054112,101,15498,102,10622,0.006355839,0.678684825,0.509681894,0.903596504,0.024799707,DB0067810054112_,3.696923459,-0.387598435,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,losartan,DB00678
,104571,DB01115,10054112,85,3515,37,2231,0.060262323,1.458023985,0.976154134,2.215434311,0.143927595,DB0111510054112_,1.938444918,0.377082084,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,nifedipine,DB01115
,104572,DB01275,10054112,77,3902,47,3302,0.084272592,1.386317835,0.949144899,2.043642266,0.185527457,DB0127510054112_,1.68455239,0.326651193,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,hydralazine,DB01275
,104590,DB00327,10069868,31,6107,20,4242,0.886838745,1.076656194,0.593510379,1.995899671,0.95298528,DB0032710069868_,0.048155821,0.073860121,NA,10069868,Device issue,10077536,Product issues,Prod,hydromorphone,DB00327
,104592,DB00497,10011224,249,19018,172,16203,0.038710459,1.233384659,1.010284805,1.508590297,0.103065156,DB0049710011224_,2.272393908,0.209762145,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,104594,DB01394,10011224,35,1405,24,1979,0.007404693,2.053712741,1.181439237,3.626275284,0.028008687,DB0139410011224_,3.575240582,0.719649248,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,colchicine,DB01394
,104596,DB01068,10028810,141,13622,50,6790,0.044420602,1.405630715,1.009863281,1.984497375,0.1144421,DB0106810028810_,2.167686258,0.34048611,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,clonazepam,DB01068
,104615,DB08895,10008479,236,27878,64,6582,0.337585163,0.870595657,0.656991843,1.16790723,0.506785452,DB0889510008479_,0.679667536,-0.138577639,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,104617,DB00203,10003997,45,13833,23,8915,0.386757685,1.260896665,0.746347812,2.185039153,0.556838701,DB0020310003997_,0.585479667,0.231823106,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,sildenafil,DB00203
,104622,DB00016,10054112,67,2695,49,2241,0.510712103,1.136963626,0.771336919,1.686133298,0.671102715,DB0001610054112_,0.398833076,0.128361223,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,erythropoietin,DB00016
,104625,DB00916,10040070,46,5277,38,2393,0.008802354,0.548962034,0.348437658,0.869550297,0.032141399,DB0091610040070_,3.43761038,-0.599725994,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,metronidazole,DB00916
,104629,DB00005,10036653,43,128039,12,42407,0.754967721,1.186808544,0.614770017,2.4725526,0.862429787,DB0000510036653_,0.14800154,0.171267809,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,104646,DB01254,10020937,41,3426,20,3128,0.020556189,1.871509568,1.068944586,3.37956028,0.063159682,DB0125410020937_,2.762089128,0.626745361,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,dasatinib,DB01254
,104647,DB00641,10007882,75,14049,81,12394,0.227519227,0.816858619,0.588041463,1.133457501,0.382754192,DB0064110007882_,0.960362291,-0.202289248,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,simvastatin,DB00641
,104648,DB01306,10007882,39,4169,43,3823,0.437630899,0.831724265,0.523858788,1.316905544,0.606081729,DB0130610007882_,0.500740436,-0.184254305,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,insulin aspart,DB01306
,104650,DB14513,10007882,48,7129,28,3536,0.541180624,0.85031298,0.521745108,1.410107533,0.696549441,DB1451310007882_,0.361616503,-0.162150786,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,magnesium,DB14513
,104681,DB06643,10022000,127,52294,14,7501,0.443811913,1.301191261,0.747086521,2.449131999,0.611853359,DB0664310022000_,0.491262635,0.2632802,NA,10022000,Influenza,10021881,Infections and infestations,Infec,denosumab,DB06643
,104691,DB00619,10002034,32,2867,20,2474,0.267583252,1.380592731,0.763506431,2.55409333,0.429902862,DB0061910002034_,0.844195998,0.322512922,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,imatinib,DB00619
,104701,DB08877,10061818,32,3257,32,3197,1,0.981578249,0.580694187,1.65917239,1,DB0887710061818_,0,-0.018593545,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,104702,DB00737,10020751,44,2757,6,926,0.032194668,2.462758728,1.040922071,7.094833676,0.089520868,DB0073710020751_,2.41328352,0.901282156,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,meclizine,DB00737
,104703,DB00814,10020751,106,8181,23,3392,0.00342327,1.910762856,1.20608737,3.149495107,0.015055745,DB0081410020751_,4.19599563,0.647502563,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,meloxicam,DB00814
,104707,DB00316,10067484,52,65422,21,36932,0.223116105,1.39785349,0.827372879,2.443556695,0.377363544,DB0031610067484_,0.974546249,0.334937839,NA,10067484,Adverse reaction,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,104719,DB00065,10010264,100,9364,43,4914,0.289680072,1.220358207,0.844002177,1.790969364,0.454847991,DB0006510010264_,0.787792002,0.199144428,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,104790,DB00158,10033557,86,16729,17,8087,0.000305964,2.445422742,1.440871064,4.393160982,0.002051077,DB0015810033557_,6.18939017,0.894218009,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,folic acid,DB00158
,104793,DB01255,10044565,34,2099,16,1562,0.150240269,1.581159669,0.845712169,3.079377033,0.284321383,DB0125510044565_,1.257650051,0.458158545,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,lisdexamfetamine,DB01255
,104799,DB00424,10016256,88,1106,27,401,0.511176662,1.181575183,0.747189043,1.921587026,0.671511748,DB0042410016256_,0.398223768,0.166848449,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,hyoscyamine,DB00424
,104805,DB05259,10022075,57,11213,12,2716,0.761522079,1.15052784,0.609330248,2.359373244,0.867834721,DB0525910022075_,0.141753996,0.140220828,NA,10022075,Injection site induration,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,104811,DB00059,10012735,26,801,51,1056,0.126049607,0.672235499,0.398596987,1.109534708,0.250176609,DB0005910012735_,1.385588173,-0.397146554,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pegaspargase,DB00059
,104861,DB00695,10061225,83,27966,39,20489,0.021727065,1.559190821,1.053017684,2.344638217,0.065999758,DB0069510061225_,2.71810421,0.444166982,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,104866,DB01225,10033661,46,4998,37,4603,0.582009391,1.144971208,0.725105582,1.81903777,0.73018552,DB0122510033661_,0.31445664,0.135379491,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,enoxaparin,DB01225
,104870,DB00480,10066901,64,67364,85,67577,0.100891186,0.755325862,0.537281737,1.057337488,0.212128531,DB0048010066901_,1.550562912,-0.280606018,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,104871,DB00682,10066901,16,19443,39,16325,0.000198674,0.344474931,0.179617736,0.631080667,0.001432449,DB0068210066901_,6.548369984,-1.065733961,male,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,104883,DB01254,10010774,72,3395,41,3107,0.017260596,1.607007584,1.076719732,2.426916389,0.055053364,DB0125410010774_,2.899452301,0.474373806,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,dasatinib,DB01254
,104885,DB01142,10012735,56,1684,17,767,0.159261447,1.500126768,0.852212849,2.772998102,0.296493174,DB0114210012735_,1.215731081,0.405549617,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,doxepin,DB01142
,104897,DB00193,10061428,289,19031,163,8539,0.024022544,0.795562029,0.653154122,0.9716278,0.071283818,DB0019310061428_,2.64108594,-0.22870646,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,tramadol,DB00193
,104899,DB00874,10011224,122,3213,70,1906,0.879203123,1.033884845,0.759920164,1.415661627,0.949253441,DB0087410011224_,0.052079455,0.033323401,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,guaifenesin,DB00874
,104900,DB00874,10028810,88,3247,35,1941,0.047167834,1.502886838,1.000627568,2.301417402,0.119766234,DB0087410028810_,2.122213486,0.407387817,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,guaifenesin,DB00874
,104903,DB00338,10023874,44,33630,7,22265,7.63122245502092e-05,4.16140757,1.859092109,10.95033761,0.000632367,DB0033810023874_,7.366041285,1.425853375,female,10023874,Laryngitis,10021881,Infections and infestations,Infec,omeprazole,DB00338
,104914,DB01254,10013710,20,3447,41,3107,0.002753485,0.439740251,0.243491102,0.769920622,0.012602359,DB0125410013710_,4.373871236,-0.821571065,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,dasatinib,DB01254
,104924,DB13867,10068319,54,4496,17,2537,0.034694668,1.792282177,1.020533027,3.305340633,0.094836662,DB1386710068319_,2.355599213,0.583489767,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,104925,DB13961,10068319,82,9375,30,6384,0.003552735,1.861217087,1.209923375,2.933560696,0.015504506,DB1396110068319_,4.166624577,0.621230621,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,104926,DB00175,10035226,35,8096,64,6042,1.45229766718634e-05,0.408153381,0.261957624,0.62665436,0.000150765,DB0017510035226_,8.799789635,-0.896112243,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pravastatin,DB00175
,104927,DB00193,10035226,96,19224,79,8623,0.000103957,0.545060888,0.400043363,0.744546794,0.000825159,DB0019310035226_,7.099934563,-0.60685777,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,tramadol,DB00193
,104930,DB00758,10035226,30,8270,50,10024,0.17794243,0.727268675,0.446038331,1.167414268,0.32125948,DB0075810035226_,1.135506134,-0.318459303,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,clopidogrel,DB00758
,104935,DB00121,10025482,144,4079,9,459,0.098653768,1.800258343,0.913862336,4.044468562,0.208846468,DB0012110025482_,1.566155902,0.587930179,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,104936,DB00627,10025482,39,1290,28,1571,0.035144045,1.695930243,1.010983616,2.87868004,0.095711674,DB0062710025482_,2.346415007,0.528231406,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,niacin,DB00627
,104955,DB00451,10039073,341,46930,49,15370,3.93164473928313e-09,2.279326719,1.6846005,3.143088724,9.65825065159413e-08,DB0045110039073_,16.1528682,0.823880101,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,104960,DB00169,10066901,79,38612,33,18142,0.613130349,1.124794639,0.740169076,1.744368408,0.75490696,DB0016910066901_,0.281160769,0.117600476,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,104995,DB00186,10013082,47,16854,16,9992,0.066734395,1.741480847,0.969092325,3.292219021,0.15544451,DB0018610013082_,1.861466463,0.554735813,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,104997,DB00476,10013082,55,17202,21,6156,0.794834907,0.937263894,0.557175667,1.633122801,0.88886159,DB0047610013082_,0.117813747,-0.064790399,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,105001,DB00275,10033425,50,2010,21,1216,0.174541932,1.440265115,0.84458603,2.537734468,0.316850354,DB0027510033425_,1.149325687,0.364827204,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,olmesartan,DB00275
,105017,DB00186,10060933,43,16858,31,9977,0.401680177,0.820935089,0.505036737,1.348637056,0.571407416,DB0018610060933_,0.55965281,-0.197311236,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,105019,DB00476,10060933,58,17199,11,6166,0.054692456,1.890353918,0.981540722,3.997135804,0.133810324,DB0047610060933_,2.011331974,0.63676407,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,105044,DB00829,10046555,35,8017,18,4436,0.886160138,1.075908703,0.592249179,2.020399432,0.952648431,DB0082910046555_,0.048509351,0.07316561,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,diazepam,DB00829
,105048,DB00555,10046571,112,6935,27,3459,0.000379705,2.06886541,1.34616338,3.2836316,0.002455843,DB0055510046571_,6.009285094,0.727000346,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,lamotrigine,DB00555
,105101,DB01068,10015090,38,13725,19,6821,1,0.993951734,0.558501594,1.826767448,1,DB0106810015090_,0,-0.00606663,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,105102,DB01222,10015090,56,9218,38,5367,0.519938284,0.858038535,0.557480071,1.333480464,0.679101484,DB0122210015090_,0.386984702,-0.153106268,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,105103,DB13961,10015090,48,9409,40,6374,0.329745654,0.812941098,0.522512811,1.270883126,0.498389331,DB1396110015090_,0.696373718,-0.207096623,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,105104,DB00215,10033318,39,11064,11,5265,0.131701574,1.687118573,0.846537193,3.655475225,0.258176776,DB0021510033318_,1.354110749,0.523022087,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,citalopram,DB00215
,105105,DB00295,10033318,43,14620,36,9566,0.300061395,0.781554094,0.489822265,1.253529879,0.466141476,DB0029510033318_,0.763266095,-0.246470913,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,morphine,DB00295
,105108,DB00736,10033318,45,10546,15,5538,0.13562324,1.575342843,0.860960238,3.045466737,0.26361435,DB0073610033318_,1.333268038,0.454472927,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,esomeprazole,DB00736
,105112,DB00321,10035664,179,7268,120,2730,2.74369921209902e-06,0.56035218,0.440202298,0.715192696,3.50088028106906e-05,DB0032110035664_,10.25991102,-0.5791898,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,amitriptyline,DB00321
,105113,DB00215,10037377,63,11040,29,5247,1,1.032454564,0.654280344,1.665020995,1,DB0021510037377_,0,0.031939039,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,105116,DB01068,10037377,102,13661,37,6803,0.10414798,1.372824335,0.932782766,2.060134375,0.217272879,DB0106810037377_,1.526601207,0.316870176,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,105117,DB13961,10037377,55,9402,59,6355,0.016303081,0.630131126,0.427712193,0.927036712,0.052597111,DB1396110037377_,2.945094088,-0.461827345,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,105120,DB00390,10000059,66,4079,34,3267,0.042251632,1.554657474,1.010101933,2.432091849,0.110200858,DB0039010000059_,2.205450594,0.441255247,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,digoxin,DB00390
,105122,DB00863,10000059,164,10509,75,5765,0.219849579,1.199511508,0.905507734,1.601453594,0.373255792,DB0086310000059_,0.985491325,0.181914397,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,105123,DB00390,10005483,34,4111,27,3274,1,1.002873601,0.585963856,1.732095458,1,DB0039010005483_,0,0.00286948,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,digoxin,DB00390
,105133,DB00207,10013950,50,9030,23,5432,0.332768058,1.307694886,0.782234194,2.248005195,0.501752956,DB0020710013950_,0.689647401,0.268265958,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,105136,DB00678,10013950,72,15527,66,10658,0.098744842,0.748838116,0.528186063,1.063135066,0.208944468,DB0067810013950_,1.565686766,-0.289232452,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,105139,DB00213,10013990,56,18839,34,13387,0.521016189,1.170369163,0.750535953,1.849726168,0.679987326,DB0021310013990_,0.385681119,0.157319223,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,105143,DB00678,10013990,41,15558,26,10698,0.804102946,1.084337371,0.647180128,1.847435297,0.894066865,DB0067810013990_,0.111974713,0.080969083,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,losartan,DB00678
,105156,DB00996,10021518,47,38906,8,22417,0.000398985,3.38501707,1.58438465,8.29635085,0.002557256,DB0099610021518_,5.968820327,1.219358949,female,10021518,Impaired gastric emptying,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,105169,DB00207,10062237,25,9055,32,5423,0.005606511,0.467905477,0.265522659,0.815879362,0.022423484,DB0020710062237_,3.797646455,-0.759488977,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,azithromycin,DB00207
,105170,DB00343,10062237,36,8700,26,5069,0.429495576,0.806761667,0.473153052,1.393233937,0.597965583,DB0034310062237_,0.514222081,-0.214726987,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,diltiazem,DB00343
,105174,DB00863,10062237,41,10632,37,5803,0.031981695,0.604804199,0.37780854,0.971252227,0.089074316,DB0086310062237_,2.418284243,-0.502850512,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,ranitidine,DB00863
,105177,DB00863,10064355,58,10615,30,5810,0.911051583,1.058188577,0.668912436,1.705629298,0.960010859,DB0086310064355_,0.040810683,0.056558557,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,105178,DB01373,10064355,94,22626,34,7347,0.606760116,0.897731706,0.599991434,1.37229828,0.749679875,DB0137310064355_,0.288108997,-0.107884023,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,105186,DB00996,10074170,43,38910,15,22410,0.101953912,1.651027459,0.898951354,3.200231625,0.213877473,DB0099610074170_,1.542351984,0.501397796,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,105200,DB08908,10051055,36,10637,17,3262,0.145110757,0.649431808,0.354912173,1.234674577,0.277207475,DB0890810051055_,1.282989047,-0.43165744,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,dimethyl fumarate,DB08908
,105204,DB00207,10018884,51,9029,41,5414,0.162115661,0.745906122,0.484014192,1.155695958,0.300201497,DB0020710018884_,1.203301372,-0.293155529,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,azithromycin,DB00207
,105207,DB00788,10018884,62,9294,60,5001,0.001561183,0.556021274,0.3829017,0.808064733,0.007944186,DB0078810018884_,4.835314998,-0.586948724,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,naproxen,DB00788
,105247,DB00169,10039163,48,38643,9,18166,0.009765001,2.507153542,1.216406242,5.813673508,0.034923878,DB0016910039163_,3.354584488,0.919148063,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,105282,DB00697,10033295,45,6051,20,1786,0.137696439,0.664143597,0.383031223,1.190569142,0.266491249,DB0069710033295_,1.322413872,-0.409256893,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,tizanidine,DB00697
,105290,DB01076,10000059,320,25427,274,25309,0.069490985,1.162458919,0.985218327,1.372329334,0.160380239,DB0107610000059_,1.830207788,0.15053752,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,105291,DB06589,10000059,36,1994,42,2611,0.645724369,1.122337741,0.695797672,1.802087181,0.781373487,DB0658910000059_,0.246702026,0.115413779,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,pazopanib,DB06589
,105295,DB01076,10005555,66,25681,79,25504,0.280072594,0.829689205,0.588852416,1.165814195,0.443926261,DB0107610005555_,0.81209681,-0.1867041,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,105298,DB01592,10005750,58,6218,27,3040,0.907853498,1.050230551,0.652977401,1.72869492,0.958771936,DB0159210005750_,0.042102046,0.049009712,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,iron,DB01592
,105299,DB06589,10005750,55,1975,74,2579,0.928285156,0.97054682,0.668451083,1.401961992,0.970147351,DB0658910005750_,0.030307311,-0.029895634,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,pazopanib,DB06589
,105300,DB01076,10012601,127,25620,104,25479,0.147165155,1.214426736,0.929167451,1.59027948,0.279982347,DB0107610012601_,1.273028725,0.194272143,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,105338,DB00433,10035742,51,7605,47,5973,0.47497709,0.852259575,0.561175632,1.296782011,0.640583497,DB0043310035742_,0.445375805,-0.159864134,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,105341,DB01137,10035742,37,7735,45,5548,0.018260018,0.589784147,0.370607684,0.933290176,0.057498001,DB0113710035742_,2.856005101,-0.527998662,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,105350,DB01039,10037377,32,2941,29,3022,0.699847092,1.133814683,0.662481994,1.948035373,0.819622255,DB0103910037377_,0.19891171,0.125587773,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fenofibrate,DB01039
,105353,DB01039,10053762,75,2898,66,2985,0.394194307,1.170446112,0.826030392,1.661756477,0.564115822,DB0103910053762_,0.57249569,0.157384968,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,fenofibrate,DB01039
,105354,DB00295,10017885,42,14621,32,9570,0.552316061,0.859090383,0.529109654,1.407081493,0.706196165,DB0029510017885_,0.347862226,-0.151881144,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,105362,DB00471,10033557,129,14060,26,5439,0.001567916,1.919287179,1.250264468,3.052322695,0.007969191,DB0047110033557_,4.832172236,0.651953856,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,montelukast,DB00471
,105363,DB00678,10033557,138,15461,51,10673,0.000101426,1.867869915,1.344157997,2.631295566,0.000807625,DB0067810033557_,7.121412505,0.624798699,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,losartan,DB00678
,105364,DB00924,10033557,81,10081,27,4224,0.341122001,1.25697698,0.802944881,2.024940919,0.510285224,DB0092410033557_,0.672785447,0.228709616,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,cyclobenzaprine,DB00924
,105398,DB01225,10005483,46,4998,81,4559,0.000326122,0.518058785,0.351861794,0.754832228,0.002160312,DB0122510005483_,6.137502677,-0.657666559,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,enoxaparin,DB01225
,105417,DB00512,10012174,60,4677,40,5058,0.020330485,1.62210062,1.067070383,2.489372625,0.062603889,DB0051210012174_,2.770927879,0.483721988,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,vancomycin,DB00512
,105418,DB00213,10013781,104,18791,41,13380,0.001250773,1.806119797,1.246058954,2.661813504,0.006616335,DB0021310013781_,5.018213762,0.591180786,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,105419,DB00295,10013781,58,14605,36,9566,0.833341702,1.05525157,0.683885682,1.648211655,0.913407226,DB0029510013781_,0.090573467,0.053779194,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,105422,DB00433,10013781,52,7604,23,5997,0.01969661,1.782981921,1.070665157,3.056361569,0.061066924,DB0043310013781_,2.795784898,0.578287199,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,105440,DB00512,10021789,57,4680,48,5050,0.23862251,1.281346605,0.855534251,1.926235751,0.396309524,DB0051210021789_,0.925559747,0.24791156,NA,10021789,Infection,10021881,Infections and infestations,Infec,vancomycin,DB00512
,105441,DB01109,10021789,35,4377,31,4239,0.80502804,1.093402001,0.653582453,1.837379429,0.894473299,DB0110910021789_,0.111520227,0.089293938,NA,10021789,Infection,10021881,Infections and infestations,Infec,heparin,DB01109
,105444,DB00213,10029151,30,18865,22,13399,1,0.968517617,0.54002917,1.762901075,1,DB0021310029151_,0,-0.031988607,NA,10029151,Nephropathy,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,105524,DB00019,10011224,85,18927,48,9481,0.519404176,0.887062704,0.614969497,1.292539592,0.678606196,DB0001910011224_,0.387714296,-0.119839607,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pegfilgrastim,DB00019
,105526,DB09270,10011224,68,3046,48,2320,0.705948186,1.079016226,0.731658031,1.602092209,0.823789037,DB0927010011224_,0.193840805,0.076049725,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ubidecarenone,DB09270
,105527,DB06769,10013968,26,641,50,1006,0.470398001,0.816204847,0.482455339,1.35205703,0.636668029,DB0676910013968_,0.451506906,-0.203089918,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bendamustine,DB06769
,105530,DB01222,10042772,63,9211,44,5361,0.366165942,0.833367792,0.557206506,1.256072601,0.535775539,DB0122210042772_,0.624039975,-0.182280207,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,105533,DB00480,10061256,21,67407,37,67625,0.047911992,0.56940893,0.316624634,0.998636267,0.121199181,DB0048010061256_,2.110319964,-0.563156422,NA,10061256,Ischaemic stroke,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,105542,DB00264,10061105,39,29568,24,24868,0.255531999,1.366687042,0.801246483,2.376515758,0.416304611,DB0026410061105_,0.876338049,0.312389594,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,metoprolol,DB00264
,105548,DB00341,10060933,36,11369,17,5051,0.881637852,0.940829319,0.514355924,1.787947271,0.950483399,DB0034110060933_,0.050784582,-0.060993538,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,105550,DB01267,10022095,34,2818,23,3692,0.015337243,1.936511228,1.105138017,3.451210329,0.050185414,DB0126710022095_,2.99203085,0.660888018,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,105553,DB00563,10019670,43,46603,23,15325,0.063617158,0.614796324,0.362218033,1.069133617,0.149997937,DB0056310019670_,1.897133738,-0.486464246,NA,10019670,Hepatic function abnormal,10019805,Hepatobiliary disorders,Hepat,methotrexate,DB00563
,105554,DB00563,10062685,49,46597,11,15337,0.295830449,1.466135882,0.75190673,3.127823848,0.46165603,DB0056310062685_,0.772935189,0.382630288,NA,10062685,Hepatic enzyme abnormal,10022891,Investigations,Inv,methotrexate,DB00563
,105555,DB00497,10028997,35,19232,29,16346,1,1.025789227,0.60882459,1.740586254,1,DB0049710028997_,0,0.025462294,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,oxycodone,DB00497
,105556,DB01029,10013573,92,1248,39,862,0.012971625,1.629016958,1.096457601,2.459356231,0.043799753,DB0102910013573_,3.128127111,0.487976739,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,irbesartan,DB01029
,105557,DB01029,10013709,78,1262,49,852,0.779961183,1.074659601,0.733882255,1.586423367,0.880223249,DB0102910013709_,0.127579711,0.072003961,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,irbesartan,DB01029
,105566,DB00193,10013654,235,19085,219,8483,1.34837822231358e-14,0.476961198,0.394347235,0.577096165,7.78947726890383e-13,DB0019310013654_,27.88083245,-0.740320137,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,105574,DB05676,10033645,38,47091,20,25309,1,1.021152919,0.579277428,1.85275957,1,DB0567610033645_,0,0.020932302,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,105575,DB00390,10000060,60,4085,24,3277,0.003841869,2.005305092,1.22707964,3.374735559,0.01651137,DB0039010000060_,4.103706047,0.695796215,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,digoxin,DB00390
,105576,DB00471,10000060,89,14100,29,5436,0.4718473,1.183167528,0.769358493,1.868795215,0.638005416,DB0047110000060_,0.449408507,0.168195188,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,105578,DB01098,10000060,64,8085,48,7161,0.39429222,1.180938877,0.798448412,1.756944443,0.564225223,DB0109810000060_,0.572301776,0.16630978,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,105580,DB01240,10000060,209,5542,74,1502,0.055197467,0.765482106,0.580686502,1.01824453,0.13467608,DB0124010000060_,2.004882788,-0.26724944,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,105581,DB08931,10000060,224,6353,88,2358,0.650442119,0.944781523,0.731567718,1.228893081,0.785013507,DB0893110000060_,0.242054356,-0.056801571,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,105582,DB00567,10003549,127,4392,55,2026,0.746561234,1.065157103,0.766745471,1.49623305,0.855570372,DB0056710003549_,0.155986931,0.063122302,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,105583,DB08931,10003549,430,6147,139,2307,0.143939584,1.160989448,0.950721946,1.424559901,0.275430565,DB0893110003549_,1.289419715,0.149272614,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,105584,DB00471,10003658,96,14093,65,5400,0.000541826,0.565943225,0.408123919,0.789025308,0.003298264,DB0047110003658_,5.714358908,-0.569261515,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,montelukast,DB00471
,105585,DB00567,10003658,31,4488,20,2061,0.230296114,0.711822502,0.391940031,1.321133535,0.386265278,DB0056710003658_,0.951230898,-0.339926694,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,cephalexin,DB00567
,105586,DB00788,10003658,43,9313,37,5024,0.045150148,0.6269376,0.393974702,1.002115698,0.115867381,DB0078810003658_,2.155309008,-0.466908266,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,naproxen,DB00788
,105587,DB08931,10007559,185,6392,64,2382,0.664607654,1.077191548,0.803133159,1.460526709,0.795845753,DB0893110007559_,0.22834989,0.074357236,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,riociguat,DB08931
,105588,DB08931,10012174,189,6388,44,2402,0.003549235,1.615130778,1.153773763,2.304340628,0.015491804,DB0893110012174_,4.167444163,0.479415931,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,riociguat,DB08931
,105589,DB00390,10020919,87,4058,34,3267,0.000287641,2.059828593,1.366924791,3.167469259,0.001949372,DB0039010020919_,6.240247898,0.722622772,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,digoxin,DB00390
,105590,DB00455,10020919,38,9363,20,5098,1,1.034517942,0.586340564,1.878641466,1,DB0045510020919_,0,0.033935562,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,loratadine,DB00455
,105594,DB01118,10020919,41,3022,27,4682,0.000647375,2.352399962,1.40929706,3.985859615,0.00383788,DB0111810020919_,5.562835249,0.855436067,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,amiodarone,DB01118
,105595,DB08931,10020919,219,6358,88,2358,0.556595139,0.922975757,0.714050132,1.201437915,0.709923488,DB0893110020919_,0.342598079,-0.080152311,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,riociguat,DB08931
,105596,DB09140,10020919,160,3581,54,1744,0.020987485,1.442917237,1.047642144,2.013636213,0.064209513,DB0914010020919_,2.7456039,0.366666923,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,oxygen,DB09140
,105597,DB00390,10020772,45,4100,31,3270,0.563356577,1.157718781,0.71481772,1.897054187,0.715353991,DB0039010020772_,0.334977766,0.146451501,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,digoxin,DB00390
,105598,DB01118,10020772,28,3035,37,4672,0.610460321,1.164903066,0.685126332,1.960394322,0.752624275,DB0111810020772_,0.284189147,0.152637878,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,amiodarone,DB01118
,105599,DB08931,10020772,72,6505,14,2432,0.027387788,1.922656561,1.072531013,3.69868703,0.078852949,DB0893110020772_,2.540170571,0.653707855,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,riociguat,DB08931
,105600,DB09140,10020772,78,3663,31,1767,0.409084372,1.213692961,0.787669221,1.911988406,0.578479811,DB0914010020772_,0.547351632,0.193667746,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,oxygen,DB09140
,105601,DB00390,10025482,159,3986,70,3231,1.86540756363336e-05,1.841042709,1.375671914,2.484741534,0.000187935,DB0039010025482_,8.579414475,0.610332101,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,105602,DB01118,10025482,67,2996,53,4656,0.000309722,1.964445103,1.345459124,2.880769209,0.002071778,DB0111810025482_,6.179348083,0.675209815,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,105603,DB08931,10025482,568,6009,153,2293,0.000169446,1.416613885,1.174942678,1.715826895,0.001253377,DB0893110025482_,6.681913699,0.348269436,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,105604,DB09140,10025482,329,3412,80,1718,2.40872706953109e-09,2.070471128,1.605133095,2.696446399,6.19201868191928e-08,DB0914010025482_,16.59741959,0.727776179,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,105605,DB00471,10033318,94,14095,20,5445,0.01540903,1.81562349,1.110427873,3.110494471,0.050354491,DB0047110033318_,2.988667468,0.59642893,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,montelukast,DB00471
,105607,DB01098,10033318,30,8119,35,7174,0.265809644,0.757394621,0.448657631,1.271255181,0.427916489,DB0109810033318_,0.84882722,-0.277870865,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,rosuvastatin,DB01098
,105609,DB00213,10034474,54,18841,32,13389,0.444611466,1.199168983,0.760052143,1.920170318,0.612679532,DB0021310034474_,0.489913266,0.181628802,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,105615,DB00588,10034474,34,16490,17,8451,1,1.024984486,0.556592435,1.957573389,1,DB0058810034474_,0,0.024677477,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,fluticasone propionate,DB00588
,105616,DB00682,10034474,107,19352,64,16300,0.031171555,1.408187915,1.022881956,1.95218057,0.087280354,DB0068210034474_,2.438629882,0.342303711,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,warfarin,DB00682
,105620,DB08931,10034474,80,6497,18,2428,0.052098349,1.660911145,0.984362823,2.950244812,0.128958354,DB0893110034474_,2.048265766,0.507366334,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,riociguat,DB08931
,105621,DB09140,10034474,52,3689,14,1784,0.063050528,1.796059081,0.977623133,3.519175807,0.149049539,DB0914010034474_,1.90347655,0.585594865,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,oxygen,DB09140
,105622,DB00390,10035598,66,4079,45,3256,0.442361187,1.170719473,0.787102035,1.755248511,0.61046169,DB0039010035598_,0.49353974,0.157618494,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,105623,DB00455,10035598,47,9354,22,5096,0.614690623,1.163848165,0.686707661,2.030492921,0.75615505,DB0045510035598_,0.279508832,0.151731899,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,105624,DB00471,10035598,56,14133,29,5436,0.224351382,0.742749126,0.465712928,1.207795935,0.378971845,DB0047110035598_,0.970293363,-0.297396941,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,105625,DB00476,10035598,51,17206,23,6154,0.356265508,0.793081654,0.475498594,1.360981913,0.525944335,DB0047610035598_,0.642559899,-0.231829094,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,105626,DB01118,10035598,40,3023,56,4653,0.674791586,1.099413139,0.711928269,1.684063722,0.802790166,DB0111810035598_,0.219661912,0.094776528,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,105627,DB08931,10035598,85,6492,31,2415,1,1.019995866,0.666860399,1.596990186,1,DB0893110035598_,0,0.019798574,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,105628,DB00213,10039163,52,18843,27,13394,0.208946059,1.368974635,0.843709233,2.268417045,0.359998865,DB0021310039163_,1.021654401,0.314062018,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,105629,DB00390,10039163,71,4074,33,3268,0.009582639,1.725735103,1.123552458,2.700295401,0.034419196,DB0039010039163_,3.369140841,0.545653106,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,digoxin,DB00390
,105634,DB00588,10039163,43,16481,18,8450,0.501807085,1.224769849,0.69119073,2.257680479,0.663230633,DB0058810039163_,0.410632486,0.202752948,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,fluticasone propionate,DB00588
,105637,DB08931,10039163,128,6449,52,2394,0.6113614,0.913787372,0.654645853,1.291417687,0.753417151,DB0893110039163_,0.28313622,-0.090157369,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,riociguat,DB08931
,105638,DB09140,10039163,110,3631,32,1766,0.010781709,1.671747018,1.113580721,2.572858589,0.03780938,DB0914010039163_,3.275198051,0.513869198,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,oxygen,DB09140
,105657,DB00203,10048865,67,13811,41,8897,0.843721103,1.052714894,0.702591531,1.594357965,0.920865722,DB0020310048865_,0.082441049,0.05137244,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,sildenafil,DB00203
,105658,DB00316,10048865,150,65324,89,36864,0.736083236,0.951114658,0.726645373,1.251054871,0.847571914,DB0031610048865_,0.165379589,-0.050120658,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,acetaminophen,DB00316
,105663,DB00476,10048865,38,17219,15,6162,0.755517707,0.906574208,0.486809415,1.77540409,0.862862608,DB0047610048865_,0.147499803,-0.09808239,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,duloxetine,DB00476
,105666,DB00588,10048865,41,16483,34,8434,0.038284066,0.617018264,0.381716987,1.003253817,0.102198414,DB0058810048865_,2.280839117,-0.482856654,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,fluticasone propionate,DB00588
,105667,DB00722,10048865,67,25336,56,25976,0.279052918,1.226643697,0.846941179,1.782467321,0.442916219,DB0072210048865_,0.814374648,0.204281738,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,lisinopril,DB00722
,105674,DB00471,10061818,63,14126,27,5438,0.63809223,0.898261393,0.563179446,1.468544249,0.775308753,DB0047110061818_,0.254493938,-0.107294169,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,105675,DB00476,10061818,75,17182,27,6150,1,0.994257743,0.632064773,1.607718046,1,DB0047610061818_,0,-0.005758807,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,105676,DB00567,10061818,36,4483,18,2063,0.769961836,0.92037998,0.507744858,1.726054223,0.873985571,DB0056710061818_,0.134691413,-0.082968673,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,105677,DB00213,10064911,111,18784,32,13389,2.15374767014304e-06,2.472395649,1.654351425,3.789944899,2.82914830133483e-05,DB0021310064911_,10.47294975,0.905187579,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,105678,DB00316,10064911,149,65325,42,36911,3.02482448654414e-05,2.004519239,1.414533794,2.895453344,0.000285947,DB0031610064911_,8.15970473,0.695404251,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,105683,DB00588,10064911,71,16453,26,8442,0.162178138,1.401134105,0.881989078,2.290046536,0.300296035,DB0058810064911_,1.202986507,0.337281984,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,105684,DB00722,10064911,50,25353,17,26015,3.84381274077372e-05,3.018026263,1.710532366,5.583682224,0.000352651,DB0072210064911_,7.950030606,1.104603062,female,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,105688,DB00982,10015090,49,3315,70,2031,5.97398342953982e-06,0.428934342,0.290221337,0.629676067,6.90224854705293e-05,DB0098210015090_,9.58107823,-0.84645142,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,isotretinoin,DB00982
,105694,DB01238,10011906,129,5121,104,3398,0.154681851,0.82307252,0.628327627,1.080228298,0.290378579,DB0123810011906_,1.236569763,-0.194710966,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,105695,DB00065,10054236,90,9374,56,4901,0.335350183,0.840281742,0.594190401,1.197177426,0.504560937,DB0006510054236_,0.68406666,-0.174018036,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,infliximab,DB00065
,105696,DB00588,10054236,67,16457,19,8449,0.022015459,1.810366334,1.073684885,3.194000901,0.066663941,DB0058810054236_,2.708091083,0.593529219,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,105697,DB00836,10054236,46,5489,21,4054,0.081730586,1.617734427,0.944350216,2.858686531,0.181267221,DB0083610054236_,1.70778298,0.481026669,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,loperamide,DB00836
,105698,DB06724,10054236,33,7896,21,3898,0.385334807,0.775806095,0.434991204,1.412980832,0.55548594,DB0672410054236_,0.58791198,-0.253852667,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,105702,DB00788,10022086,162,9194,44,5017,1.80631864513864e-05,2.009014038,1.429030711,2.876470831,0.000182507,DB0078810022086_,8.608724356,0.697644073,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,105708,DB00193,10005734,56,19264,24,8678,0.904068377,1.051112141,0.640381327,1.774594801,0.957450283,DB0019310005734_,0.043481484,0.049848786,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,tramadol,DB00193
,105709,DB00706,10005734,6,1069,81,15844,0.82336464,1.097851936,0.390487244,2.503021143,0.906247631,DB0070610005734_,0.098442687,0.093355485,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,tamsulosin,DB00706
,105718,DB00996,10038063,73,38880,48,22377,0.50847594,0.875306775,0.599652363,1.287985547,0.668983661,DB0099610038063_,0.401995642,-0.133180854,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,105726,DB01164,10007559,37,6487,47,7889,0.912576385,0.957369853,0.604200488,1.506868563,0.960751003,DB0116410007559_,0.040040006,-0.043565491,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,calcium chloride,DB01164
,105794,DB06724,10051055,54,7875,51,3868,0.0011291,0.5200786,0.347357898,0.779709284,0.006089123,DB0672410051055_,5.101251139,-0.653775326,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,calcium carbonate,DB06724
,105796,DB00316,10028997,95,65379,57,36896,0.735549996,0.940568232,0.670116519,1.330491755,0.847238699,DB0031610028997_,0.165772807,-0.061271085,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,105812,DB08868,10016173,452,8750,116,2395,0.564686297,1.066521928,0.863279145,1.326137169,0.716402216,DB0886810016173_,0.333513516,0.064402819,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,fingolimod,DB08868
,105814,DB08868,10016322,196,9006,38,2473,0.053233232,1.416277302,0.993329573,2.067168699,0.131082065,DB0886810016322_,2.031931699,0.348031811,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,105818,DB08868,10061224,79,9123,26,2485,0.403602624,0.827650962,0.524149599,1.346647251,0.573334503,DB0886810061224_,0.556285958,-0.189163757,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,fingolimod,DB08868
,105822,DB01217,10013968,110,2644,6,262,0.1828026,1.816404273,0.797171989,5.106570331,0.32743646,DB0121710013968_,1.116461257,0.596858873,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,anastrozole,DB01217
,105826,DB00343,10010305,73,8663,48,5047,0.509321416,0.88603741,0.606154127,1.305567683,0.66986132,DB0034310010305_,0.400684573,-0.120996105,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,diltiazem,DB00343
,105827,DB00581,10010305,63,2050,77,1992,0.197488605,0.79507897,0.557311205,1.130696907,0.345995506,DB0058110010305_,1.061329493,-0.229313835,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,lactulose,DB00581
,105828,DB01118,10010305,30,3033,47,4662,1,0.981124112,0.597656714,1.588065411,1,DB0111810010305_,0,-0.019056311,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,amiodarone,DB01118
,105831,DB00588,10019063,70,16454,49,8419,0.098935109,0.730935411,0.499704676,1.076646039,0.209263173,DB0058810019063_,1.564162616,-0.31343018,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,105832,DB00682,10019063,44,19415,51,16313,0.122639614,0.724913861,0.47282086,1.107427343,0.24520767,DB0068210019063_,1.405649795,-0.321702444,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,105835,DB00341,10044565,124,11281,50,5018,0.620419798,1.103141418,0.786892224,1.567000415,0.760959118,DB0034110044565_,0.273175643,0.098161944,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,105836,DB00581,10044565,31,2082,24,2045,0.417100608,1.268637254,0.717884759,2.267482121,0.586235836,DB0058110044565_,0.53403312,0.237943296,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,lactulose,DB00581
,105837,DB00682,10044565,161,19298,107,16257,0.064651413,1.267555172,0.985592021,1.635663307,0.15183724,DB0068210044565_,1.884946122,0.237089984,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,105842,DB00635,10049414,63,32990,76,23718,0.002508,0.595987007,0.419707926,0.843732194,0.011689473,DB0063510049414_,4.449066565,-0.517536412,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,105851,DB01068,10064355,57,13706,32,6808,0.574386859,0.884787406,0.563536348,1.411415824,0.72416522,DB0106810064355_,0.322735708,-0.122407882,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,105852,DB00656,10067482,40,11973,22,6597,1,1.001799411,0.580662068,1.771350489,1,DB0065610067482_,0,0.001797794,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,105853,DB01068,10067482,70,13693,24,6816,0.124681605,1.451812095,0.900787099,2.416457626,0.248098412,DB0106810067482_,1.393929788,0.372812497,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,105855,DB01164,10013709,71,6453,41,7895,0.000118606,2.118586837,1.420423629,3.197269234,0.000922222,DB0116410013709_,6.988724874,0.75074928,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,105876,DB00422,10003988,51,3384,27,2922,0.040114493,1.63088271,1.000834989,2.712572739,0.105906935,DB0042210003988_,2.245194546,0.489121408,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,methylphenidate,DB00422
,105881,DB00182,10022998,62,5132,49,2803,0.057787098,0.691088763,0.466082072,1.029723874,0.139319778,DB0018210022998_,1.970983427,-0.369487007,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,105882,DB00404,10022998,87,19805,50,9812,0.413541616,0.862061816,0.601413924,1.247402242,0.582916818,DB0040410022998_,0.539710782,-0.148428298,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,105912,DB00316,10033664,108,65366,36,36917,0.005334144,1.694312189,1.151938529,2.544952806,0.021540632,DB0031610033664_,3.837814246,0.52727687,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,105913,DB00635,10033664,46,33007,10,23784,0.00019538,3.314541659,1.649569736,7.369307188,0.001412809,DB0063510033664_,6.56217513,1.198319351,female,10033664,Panic attack,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,105914,DB08932,10033664,51,19392,8,6589,0.036038477,2.166165504,1.01967997,5.28795177,0.097612673,DB0893210033664_,2.326747946,0.772958555,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,macitentan,DB08932
,105916,DB00316,10037383,38,65436,20,36933,0.891515483,1.072392565,0.608416993,1.945618379,0.954929174,DB0031610037383_,0.046118104,0.069892194,NA,10037383,Pulmonary fibrosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,105917,DB00635,10037383,58,32995,32,23762,0.240825183,1.305300819,0.833391948,2.077947605,0.398846319,DB0063510037383_,0.919179102,0.266433527,NA,10037383,Pulmonary fibrosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,105918,DB08932,10037383,64,19379,35,6562,0.027255789,0.619192759,0.403494849,0.964444008,0.078571882,DB0893210037383_,2.543741377,-0.47933865,NA,10037383,Pulmonary fibrosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,105919,DB00204,10012735,32,932,20,1023,0.050095457,1.755718512,0.966121425,3.263531394,0.125191015,DB0020410012735_,2.077914589,0.562878182,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dofetilide,DB00204
,105920,DB00158,10013710,46,16769,85,8019,3.27284395775714e-14,0.258808421,0.17656099,0.375180295,1.7884969527993e-12,DB0015810013710_,27.04964554,-1.351667177,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,105926,DB00252,10013887,18,2214,32,1876,0.014450944,0.476706336,0.251056606,0.878539597,0.04781509,DB0025210013887_,3.040413999,-0.740854626,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,phenytoin,DB00252
,105929,DB00158,10017577,241,16574,90,8014,0.038630496,1.29481697,1.010685332,1.670916932,0.102877669,DB0015810017577_,2.274214674,0.258369349,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,105930,DB00252,10017577,27,2205,32,1876,0.236710624,0.717920857,0.412138284,1.241961493,0.393993083,DB0025210017577_,0.931421926,-0.331395943,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,phenytoin,DB00252
,105941,DB00158,10047340,46,16769,21,8083,0.896687664,1.055851351,0.616996651,1.864096422,0.956301489,DB0015810047340_,0.044682051,0.054347409,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,folic acid,DB00158
,105954,DB00126,10001760,194,9977,26,5919,4.99544062319232e-17,4.426356196,2.926067353,6.955396644,3.82813868165044e-15,DB0012610001760_,33.19639769,1.487576717,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,ascorbic acid,DB00126
,105956,DB00745,10003239,60,2517,21,1062,0.538722876,1.205442886,0.718380551,2.097745205,0.694610556,DB0074510003239_,0.364403942,0.18684704,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,modafinil,DB00745
,105961,DB00745,10013968,80,2497,28,1055,0.454157421,1.207087163,0.770863618,1.94062452,0.621620468,DB0074510013968_,0.475425552,0.188210154,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,modafinil,DB00745
,105996,DB00213,10041349,195,18700,103,13318,0.015348061,1.348312494,1.05543847,1.730769148,0.050211438,DB0021310041349_,2.991512437,0.298853806,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,105998,DB00950,10041349,56,4662,25,2031,0.903709335,0.975858764,0.596973434,1.637077126,0.957417047,DB0095010041349_,0.043516196,-0.024437412,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,fexofenadine,DB00950
,106013,DB00181,10065154,75,9781,22,5849,0.002981991,2.038537187,1.251687357,3.448294252,0.013439922,DB0018110065154_,4.309525728,0.712232486,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,baclofen,DB00181
,106015,DB00441,10013709,56,2218,37,1857,0.293001169,1.267102716,0.817687774,1.983965229,0.458574874,DB0044110013709_,0.779631699,0.236732969,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,gemcitabine,DB00441
,106026,DB00916,10010305,40,5283,32,2399,0.020985447,0.56769217,0.346768987,0.936083831,0.064207016,DB0091610010305_,2.745642785,-0.566175962,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,metronidazole,DB00916
,106028,DB01212,10011224,42,1977,38,1903,0.821807078,1.063901659,0.666254202,1.703696012,0.905122417,DB0121210011224_,0.099685077,0.061942961,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ceftriaxone,DB01212
,106029,DB01164,10016256,34,6490,30,7906,0.209528768,1.380562623,0.818980936,2.338186518,0.360648528,DB0116410016256_,1.019851401,0.322491114,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,106031,DB00916,10029354,33,5290,38,2393,0.000145906,0.39289267,0.238150971,0.645132046,0.001100627,DB0091610029354_,6.811875074,-0.934218809,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,metronidazole,DB00916
,106033,DB01212,10029354,26,1993,51,1890,0.002587251,0.483546322,0.288106382,0.793877109,0.011986585,DB0121210029354_,4.423967201,-0.726608164,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,ceftriaxone,DB01212
,106034,DB00916,10047895,70,5253,42,2389,0.181846331,0.757983047,0.508128106,1.14289957,0.326223778,DB0091610047895_,1.120171697,-0.277094259,NA,10047895,Weight decreased,10022891,Investigations,Inv,metronidazole,DB00916
,106042,DB00297,10053762,63,1609,40,839,0.342382727,0.821349196,0.538816205,1.264607695,0.511714901,DB0029710053762_,0.669987642,-0.196806929,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,bupivacaine,DB00297
,106043,DB00745,10033371,100,2477,33,1050,0.245796302,1.284423974,0.852486066,1.979430296,0.404695155,DB0074510033371_,0.904621198,0.250310348,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,modafinil,DB00745
,106048,DB00476,10013496,224,17033,65,6112,0.139687562,1.236571917,0.93276209,1.658704903,0.269363038,DB0047610013496_,1.311695225,0.212342968,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,106050,DB06403,10008190,83,21388,31,6630,0.377711121,0.829952612,0.542809972,1.298810992,0.54770382,DB0640310008190_,0.602020613,-0.186386674,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,106060,DB00471,10006784,56,14133,16,5449,0.356166251,1.34937895,0.762348194,2.522334114,0.525842105,DB0047110006784_,0.642754292,0.29964445,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,106061,DB00471,10022052,61,14128,12,5453,0.035248504,1.961979862,1.044922805,4.00670737,0.095951421,DB0047110022052_,2.34391325,0.673954097,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,106062,DB00471,10022086,150,14039,37,5428,0.013699301,1.567470451,1.085918028,2.314413537,0.045754272,DB0047110022086_,3.084470116,0.449463143,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,106072,DB00338,10038743,43,33631,19,22253,0.154386829,1.497477655,0.853918607,2.721641916,0.289995913,DB0033810038743_,1.237888451,0.403782129,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,106073,DB01156,10038743,49,13573,20,6308,0.698379845,1.138614573,0.6637829,2.024035625,0.818627998,DB0115610038743_,0.200125514,0.129812236,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,106081,DB00563,10051792,146,46500,51,15297,0.740840323,0.941746412,0.679952191,1.322899877,0.851278159,DB0056310051792_,0.161016343,-0.060019242,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,106091,DB01222,10046735,113,9161,25,5380,1.95539135956802e-06,2.654306817,1.706769562,4.279724687,2.59714309682897e-05,DB0122210046735_,10.55851343,0.976183535,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,budesonide,DB01222
,106094,DB05351,10037844,68,2655,28,1103,1,1.008931807,0.636867606,1.637138423,1,DB0535110037844_,0,0.008892154,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dexlansoprazole,DB05351
,106119,DB00343,10043554,39,8697,46,5049,0.001433362,0.492217138,0.312402391,0.77213701,0.007405587,DB0034310043554_,4.905520624,-0.708835322,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,diltiazem,DB00343
,106124,DB00571,10011906,145,4978,134,2475,5.73403448950909e-07,0.538025787,0.420284953,0.689170205,8.75002011940472e-06,DB0057110011906_,11.64645456,-0.619848789,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,106141,DB01050,10048865,41,18067,26,9345,0.439579171,0.815670883,0.486793335,1.389758321,0.607927575,DB0105010048865_,0.497699523,-0.203744335,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,ibuprofen,DB01050
,106154,DB00575,10042772,36,5208,44,3785,0.022720566,0.59467524,0.371105009,0.94730187,0.068240883,DB0057510042772_,2.684711433,-0.519739838,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,106156,DB00959,10042772,46,8032,25,4977,0.626675106,1.140166208,0.685039446,1.939126558,0.766200207,DB0095910042772_,0.266311776,0.131174048,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,106157,DB01015,10042772,58,9829,62,9319,0.522730775,0.886950265,0.608437319,1.291341204,0.681208647,DB0101510042772_,0.383886636,-0.11996637,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,106247,DB06186,10003239,23,2186,40,3606,0.896569628,0.94851721,0.540533855,1.628158984,0.956301489,DB0618610003239_,0.044682051,-0.052855345,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ipilimumab,DB06186
,106254,DB00820,10003997,42,11873,9,5807,0.024021926,2.28234338,1.094125588,5.335844429,0.071283818,DB0082010003997_,2.64108594,0.825202713,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,tadalafil,DB00820
,106258,DB01068,10039897,74,13689,50,6790,0.10358202,0.734091773,0.505296554,1.074356473,0.216401334,DB0106810039897_,1.530620565,-0.309121227,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,106265,DB00051,10002198,86,25645,17,11403,0.001246246,2.24935491,1.325690523,4.039612111,0.006595707,DB0005110002198_,5.021336366,0.810643469,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,adalimumab,DB00051
,106266,DB00065,10002198,129,9335,46,4911,0.024752434,1.475286893,1.044033204,2.117012064,0.072951474,DB0006510002198_,2.617960804,0.388852474,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,infliximab,DB00065
,106267,DB00051,10016717,30,25701,21,11399,0.127782757,0.633613608,0.350718551,1.164905465,0.252520094,DB0005110016717_,1.376264452,-0.456315961,NA,10016717,Fistula,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,106269,DB00051,10054236,74,25657,59,11361,0.000932303,0.555416428,0.388860664,0.796298731,0.005197918,DB0005110054236_,5.259497044,-0.588037125,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,adalimumab,DB00051
,106281,DB00480,10060084,69,67359,83,67579,0.291492824,0.834042714,0.597009245,1.162052141,0.456948793,DB0048010060084_,0.783183944,-0.181470662,NA,10060084,Light chain analysis increased,10022891,Investigations,Inv,lenalidomide,DB00480
,106282,DB00188,10061822,68,7818,67,8761,0.488997595,1.137334846,0.798386465,1.620492217,0.652422465,DB0018810061822_,0.427062975,0.128687671,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,106294,DB09053,10047943,59,2226,69,3983,0.019847483,1.529950024,1.057746239,2.20674974,0.061379034,DB0905310047943_,2.790686968,0.425235071,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,ibrutinib,DB09053
,106295,DB00169,10018985,34,38657,21,18154,0.315003498,0.760308833,0.428622155,1.379073291,0.48255191,DB0016910018985_,0.728666778,-0.274030569,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,106297,DB00695,10018985,40,28009,47,20481,0.029588733,0.622342002,0.397632035,0.969798236,0.083812689,DB0069510018985_,2.47917086,-0.474265495,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,106317,DB00624,10008479,7,555,54,4342,1,1.014145788,0.387359166,2.250545954,1,DB0062410008479_,0,0.01404667,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,testosterone,DB00624
,106318,DB00956,10008479,78,5736,44,3423,0.850641384,1.057887114,0.720002659,1.571610791,0.926255979,DB0095610008479_,0.076604647,0.05627363,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,106319,DB00624,10012735,13,549,119,4277,0.677221838,0.851116167,0.437214149,1.525070564,0.804245873,DB0062410012735_,0.217850245,-0.161206653,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,testosterone,DB00624
,106320,DB00650,10020772,36,2095,36,1978,0.81331955,0.944140926,0.575532672,1.548859921,0.899770802,DB0065010020772_,0.105615213,-0.057479838,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,leucovorin,DB00650
,106322,DB00231,10002034,62,3234,38,2101,0.836629796,1.059967824,0.693804722,1.638114307,0.915625842,DB0023110002034_,0.088147467,0.058238553,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,temazepam,DB00231
,106328,DB01212,10002034,44,1975,36,1905,0.499072457,1.178852944,0.737996593,1.894127302,0.660978991,DB0121210002034_,0.414033224,0.164541884,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ceftriaxone,DB01212
,106331,DB11074,10002034,32,1228,29,839,0.291959421,0.75401618,0.43812105,1.302557444,0.457425382,DB1107410002034_,0.782141508,-0.282341452,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,dimethicone,DB11074
,106344,DB00887,10020646,34,2307,32,1783,0.454204389,0.82121233,0.489588821,1.380474247,0.621664837,DB0088710020646_,0.475354179,-0.196973579,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,bumetanide,DB00887
,106345,DB00927,10020646,23,7474,30,4986,0.016583222,0.511471358,0.283383904,0.911862325,0.053310084,DB0092710020646_,2.931629768,-0.670463691,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,famotidine,DB00927
,106357,DB00193,10033645,39,19281,23,8679,0.336028096,0.76325069,0.444376177,1.339556724,0.505148639,DB0019310033645_,0.682902559,-0.270168744,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,106365,DB00656,10033645,39,11974,25,6594,0.601095238,0.859095052,0.506434535,1.482545369,0.745343349,DB0065610033645_,0.293910295,-0.151875709,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,106374,DB01039,10033645,33,2940,36,3015,0.809965822,0.940037717,0.566342891,1.555702434,0.89770415,DB0103910033645_,0.107914719,-0.06183528,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,fenofibrate,DB01039
,106422,DB00103,10051792,18,376,65,593,0.001972353,0.437053413,0.240028834,0.75993274,0.009622886,DB0010310051792_,4.643611034,-0.827699865,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,agalsidase beta,DB00103
,106457,DB00959,10047571,69,8009,19,4983,0.001273781,2.259347209,1.341907048,3.98177813,0.006712374,DB0095910047571_,5.003802582,0.815075926,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,methylprednisolone,DB00959
,106459,DB01060,10037844,358,8229,198,4883,0.446625342,1.072899549,0.896008755,1.287583323,0.614378321,DB0106010037844_,0.487144382,0.070364843,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,amoxicillin,DB01060
,106460,DB08868,10024855,57,9145,8,2503,0.093656424,1.949980885,0.924110118,4.73968245,0.201189857,DB0886810024855_,1.603506253,0.66781957,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,106461,DB08868,10041466,70,9132,17,2494,0.793080232,1.124540738,0.653369391,2.042310879,0.887854389,DB0886810041466_,0.118947526,0.11737472,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,106464,DB08868,10050584,99,9103,11,2500,0.002232313,2.471630652,1.32040107,5.11909446,0.010640373,DB0886810050584_,4.543099703,0.904878116,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,fingolimod,DB08868
,106478,DB00019,10000087,56,18956,16,9513,0.045472552,1.756430762,0.992720509,3.282302645,0.116467336,DB0001910000087_,2.150144425,0.563283774,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,pegfilgrastim,DB00019
,106480,DB00019,10012735,209,18803,88,9441,0.17401101,1.192461305,0.92402745,1.54970738,0.316170421,DB0001910012735_,1.151473904,0.176019494,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pegfilgrastim,DB00019
,106481,DB00019,10016322,126,18886,25,9504,5.26728081384022e-06,2.536205359,1.640160923,4.069836384,6.18911382171615e-05,DB0001910016322_,9.690133551,0.930669011,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,106482,DB00019,10016334,43,18969,13,9516,0.119273863,1.659311859,0.875299054,3.365126607,0.240220174,DB0001910016334_,1.426199383,0.506402973,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,106500,DB00012,10012735,128,1518,76,1237,0.034370183,1.372296012,1.014472402,1.866457344,0.094150411,DB0001210012735_,2.362861661,0.316485258,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,darbepoetin alfa,DB00012
,106510,DB00688,10020646,20,6470,41,5337,0.000690647,0.402411053,0.223073797,0.703774812,0.004046735,DB0068810020646_,5.509844958,-0.910281192,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,mycophenolate mofetil,DB00688
,106520,DB00688,10022437,47,6443,48,5330,0.351799931,0.810037682,0.529173942,1.239378116,0.521545834,DB0068810022437_,0.65095812,-0.210674512,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,mycophenolate mofetil,DB00688
,106524,DB00927,10022437,118,7379,61,4955,0.106733175,1.298940618,0.943557488,1.803726098,0.221227309,DB0092710022437_,1.508564558,0.261549023,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,famotidine,DB00927
,106526,DB01015,10022437,126,9761,90,9291,0.039987576,1.332565486,1.007101089,1.76923191,0.10565676,DB0101510022437_,2.247559555,0.287106021,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,sulfamethoxazole,DB01015
,106640,DB00864,10038540,28,6841,51,8341,0.090012363,0.669419544,0.40596109,1.083158857,0.195211302,DB0086410038540_,1.633672707,-0.401344294,NA,10038540,Renal tubular necrosis,10038359,Renal and urinary disorders,Renal,tacrolimus,DB00864
,106715,DB00153,10064355,35,7388,15,3424,0.879656634,1.081384112,0.574586738,2.134244528,0.949457398,DB0015310064355_,0.051864617,0.078241805,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,ergocalciferol,DB00153
,106718,DB00437,10064355,25,6896,60,11486,0.144086738,0.69401455,0.416527964,1.124996358,0.27567201,DB0043710064355_,1.288543488,-0.365262353,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,allopurinol,DB00437
,106720,DB00688,10064355,38,6452,20,5358,0.112459894,1.577773896,0.89406734,2.865572387,0.229771341,DB0068810064355_,1.470670632,0.456014927,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,mycophenolate mofetil,DB00688
,106726,DB01015,10064355,18,9869,33,9348,0.024519105,0.516680255,0.273710465,0.945404338,0.072438426,DB0101510064355_,2.625018372,-0.660331058,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,sulfamethoxazole,DB01015
,106745,DB00688,10065381,37,6453,67,5311,9.82480669707672e-05,0.454534643,0.295187238,0.690271636,0.00078482,DB0068810065381_,7.150056077,-0.788481145,NA,10065381,Polyomavirus-associated nephropathy,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,106752,DB00864,10065381,48,6821,86,8306,0.036038889,0.679670245,0.466489072,0.980136328,0.097612673,DB0086410065381_,2.326747946,-0.386147533,NA,10065381,Polyomavirus-associated nephropathy,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,106785,DB00864,10067757,20,6849,46,8346,0.018034119,0.529841158,0.296590838,0.914779386,0.05693118,DB0086410067757_,2.865912113,-0.63517802,NA,10067757,Focal segmental glomerulosclerosis,10038359,Renal and urinary disorders,Renal,tacrolimus,DB00864
,106799,DB01268,10041349,24,2119,34,3096,0.894078988,1.03135198,0.583336508,1.796981734,0.955860142,DB0126810041349_,0.045143671,0.030870544,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,sunitinib,DB01268
,106844,DB00563,10046851,42,46604,10,15338,0.423357038,1.382249077,0.682272361,3.090119028,0.59219248,DB0056310046851_,0.523923561,0.323711938,NA,10046851,Uveitis,10015919,Eye disorders,Eye,methotrexate,DB00563
,106872,DB00904,10040829,86,22983,38,14418,0.07887597,1.419741105,0.957934043,2.139544024,0.176454039,DB0090410040829_,1.734694836,0.350474535,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,106884,DB01039,10003658,28,2945,48,3003,0.028632644,0.594875372,0.358324505,0.970534971,0.081681033,DB0103910003658_,2.504933453,-0.519403354,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,fenofibrate,DB01039
,106885,DB00343,10007515,125,8611,107,4988,0.003856174,0.676751234,0.517275749,0.886584673,0.016559308,DB0034310007515_,4.100806896,-0.390451528,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,diltiazem,DB00343
,106889,DB00695,10008111,56,27993,69,20459,0.003667787,0.593182237,0.409160871,0.856721731,0.015916754,DB0069510008111_,4.140383013,-0.522253613,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,106899,DB00175,10019196,31,8100,23,6083,1,1.012200419,0.570741536,1.819779051,1,DB0017510019196_,0,0.012126593,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,106900,DB00343,10019196,33,8703,25,5070,0.340881422,0.769007563,0.442999832,1.350559186,0.510109204,DB0034310019196_,0.673130451,-0.262654475,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,106901,DB00588,10019196,53,16471,26,8442,0.905705253,1.044785154,0.641277399,1.74194277,0.957861963,DB0058810019196_,0.0430516,0.04381127,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,106902,DB00904,10019196,70,22999,37,14419,0.427483262,1.186057149,0.784946442,1.8185976,0.59604793,DB0090410019196_,0.517434196,0.170634486,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,106924,DB00695,10047290,35,28014,32,20496,0.38740177,0.800234293,0.480979949,1.335548595,0.557475941,DB0069510047290_,0.584335932,-0.222850728,NA,10047290,Ventricular fibrillation,10007541,Cardiac disorders,Card,furosemide,DB00695
,106925,DB00904,10047290,41,23028,23,14433,0.701945866,1.117283582,0.654551436,1.951252677,0.82110532,DB0090410047290_,0.197103895,0.110900366,NA,10047290,Ventricular fibrillation,10007541,Cardiac disorders,Card,ondansetron,DB00904
,106945,DB08932,10009887,52,19391,8,6589,0.036301382,2.208753914,1.041182676,5.386811363,0.09813152,DB0893210009887_,2.321446659,0.792428517,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,106946,DB00564,10013968,66,2538,22,1441,0.032561165,1.703104109,1.032223876,2.911498389,0.090334079,DB0056410013968_,2.404240493,0.532452532,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carbamazepine,DB00564
,106947,DB00814,10013968,254,8033,110,3305,0.681838013,0.950025994,0.753718706,1.203816711,0.807559819,DB0081410013968_,0.213738148,-0.051265933,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,meloxicam,DB00814
,106953,DB06228,10047924,33,15879,20,16056,0.074369781,1.668355268,0.928914939,3.069617005,0.168809127,DB0622810047924_,1.778986628,0.511838272,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,106957,DB09072,10010071,46,6425,34,2501,0.005756485,0.526659582,0.329927495,0.8482775,0.022907151,DB0907210010071_,3.776306156,-0.641200894,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,106970,DB00404,10047461,63,19829,17,9845,0.023646499,1.839918184,1.062715961,3.355976555,0.07040646,DB0040410047461_,2.653470256,0.609721105,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,alprazolam,DB00404
,106973,DB00177,10015150,37,4763,22,2828,1,0.998568648,0.57243569,1.780859032,1,DB0017710015150_,0,-0.001432377,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,valsartan,DB00177
,106993,DB00619,10016807,59,2840,34,2460,0.059754481,1.502991754,0.965673986,2.372799165,0.143020082,DB0061910016807_,1.944770224,0.407457625,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,imatinib,DB00619
,106996,DB00169,10000269,33,38658,18,18157,0.652620105,0.861097533,0.470801219,1.624790216,0.786830849,DB0016910000269_,0.239741985,-0.149547502,NA,10000269,Abscess,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,107012,DB00542,10003988,37,1649,23,1401,0.295250678,1.36661981,0.786527494,2.421477313,0.461174359,DB0054210003988_,0.773979088,0.312340399,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,benazepril,DB00542
,107013,DB13867,10003988,111,4439,38,2516,0.007315161,1.655526766,1.131873996,2.468609043,0.027724192,DB1386710003988_,3.585449906,0.504119246,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone,DB13867
,107015,DB00455,10007882,65,9336,45,5073,0.229417474,0.78491402,0.52768073,1.176591723,0.385183373,DB0045510007882_,0.954035764,-0.242181096,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,loratadine,DB00455
,107017,DB00836,10007882,59,5476,30,4045,0.106092199,1.452676975,0.919007789,2.340175743,0.220340822,DB0083610007882_,1.51257974,0.373408044,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,loperamide,DB00836
,107018,DB00863,10007882,73,10600,34,5806,0.478439233,1.175988261,0.771617551,1.824869772,0.643739614,DB0086310007882_,0.44046096,0.162108867,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,ranitidine,DB00863
,107019,DB13867,10007882,54,4496,21,2533,0.182882631,1.448644816,0.85824439,2.531478487,0.327524014,DB1386710007882_,1.116193902,0.37062851,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,fluticasone,DB13867
,107020,DB00567,10017577,56,4463,23,2058,0.715441929,1.122714662,0.677562344,1.917368404,0.831526656,DB0056710017577_,0.184491923,0.115749558,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,107021,DB00761,10017577,218,15089,86,8539,0.00465046,1.434492646,1.111025005,1.866132716,0.019286421,DB0076110017577_,3.94835398,0.36081123,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,107022,DB00863,10017577,172,10501,57,5783,0.000797781,1.661742229,1.222631183,2.287427417,0.00456408,DB0086310017577_,5.389538409,0.507866588,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,107023,DB13867,10017577,62,4488,25,2529,0.177727053,1.397423994,0.862883839,2.327026933,0.320958817,DB1386710017577_,1.136442461,0.334630537,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,107032,DB00996,10017822,45,38908,16,22409,0.110175204,1.619842227,0.897916906,3.070988069,0.226308383,DB0099610017822_,1.485856682,0.482328754,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,107034,DB01050,10017822,55,18053,44,9327,0.03350228,0.645797138,0.426180722,0.983700429,0.092355263,DB0105010017822_,2.382112579,-0.437269852,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,107037,DB00374,10037844,231,17485,86,5638,0.263258311,0.866136833,0.672042537,1.124888118,0.425058799,DB0037410037844_,0.85552777,-0.143712377,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,treprostinil,DB00374
,107038,DB00542,10037844,54,1632,24,1400,0.007816553,1.929754438,1.165586383,3.282128829,0.02923214,DB0054210037844_,3.532486497,0.65739276,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,benazepril,DB00542
,107039,DB01190,10037844,288,4646,145,2140,0.394391769,0.914883447,0.741649897,1.132328872,0.564306233,DB0119010037844_,0.572158208,-0.088958602,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,clindamycin,DB01190
,107040,DB13867,10037844,114,4436,58,2496,0.573889287,1.105934523,0.796021131,1.55056249,0.723728826,DB1386710037844_,0.323338507,0.100690699,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone,DB13867
,107046,DB00381,10048634,41,29319,9,22878,0.00016027,3.554622089,1.701366503,8.32078592,0.001193906,DB0038110048634_,6.730524963,1.268248754,female,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,107061,DB00169,10053483,45,38646,10,18165,0.029514602,2.115136292,1.050559663,4.708421489,0.083643267,DB0016910053483_,2.481194346,0.749119251,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,107064,DB00381,10053483,47,29313,10,22877,4.17613035823925e-05,3.667923437,1.828668698,8.1431616,0.000378516,DB0038110053483_,7.879252702,1.299625681,female,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,107069,DB00695,10053483,59,27990,15,20513,8.29995541150467e-05,2.882508042,1.614008568,5.473580357,0.000680488,DB0069510053483_,7.292700942,1.058660763,female,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,107072,DB00996,10053483,49,38904,8,22417,0.000267263,3.529241509,1.657271364,8.630658485,0.001836844,DB0099610053483_,6.299706239,1.261082978,female,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,107082,DB00374,10053484,83,17633,14,5710,0.02369752,1.91967439,1.081276675,3.666371802,0.070530409,DB0037410053484_,2.651711328,0.652155583,NA,10053484,Infusion site warmth,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,107123,DB00374,10054997,203,17513,41,5683,0.004390046,1.606596491,1.14226447,2.309054034,0.018412695,DB0037410054997_,3.994714908,0.474117961,NA,10054997,Infusion site infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,107131,DB00820,10054997,77,11838,20,5796,0.009200439,1.884937618,1.1393145,3.258792968,0.033310404,DB0082010054997_,3.401885506,0.633894727,NA,10054997,Infusion site infection,10021881,Infections and infestations,Infec,tadalafil,DB00820
,107143,DB00381,10061218,49,29311,22,22865,0.031117386,1.737429191,1.030528069,3.018695852,0.087175113,DB0038110061218_,2.439836385,0.552406544,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,107148,DB00695,10061218,50,27999,21,20507,0.030710818,1.743829146,1.028105203,3.057817139,0.086289029,DB0069510061218_,2.450052819,0.556083354,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,107168,DB00820,10065464,54,11861,7,5809,0.000176798,3.777645929,1.712349447,9.849109465,0.001299172,DB0082010065464_,6.646028524,1.329101046,female,10065464,Infusion site haemorrhage,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,107220,DB00181,10023232,58,9798,22,5849,0.081577914,1.573756647,0.947391989,2.703292588,0.180997338,DB0018110023232_,1.709272954,0.45346553,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,107222,DB01592,10023232,71,6205,14,3053,0.001026988,2.49505523,1.391030971,4.801859766,0.005631452,DB0159210023232_,5.179387912,0.914310865,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,iron,DB01592
,107224,DB00997,10024384,33,5298,23,3491,0.891267339,0.94543306,0.537580582,1.689354155,0.954816394,DB0099710024384_,0.046236214,-0.056112192,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,doxorubicin,DB00997
,107231,DB09401,10008479,27,733,32,728,0.595660765,0.838093044,0.477753602,1.460287702,0.74122358,DB0940110008479_,0.299452972,-0.176626153,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,isosorbide,DB09401
,107233,DB00047,10029148,26,9259,31,8487,0.353836785,0.768793993,0.438026382,1.339219779,0.52367483,DB0004710029148_,0.64688434,-0.262932235,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,insulin glargine,DB00047
,107236,DB00996,10029148,106,38847,61,22364,1,1.000360947,0.722995829,1.394862094,1,DB0099610029148_,0,0.000360882,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,107264,DB09068,10016256,82,2313,30,956,0.672411725,1.129686305,0.729749529,1.790851104,0.801085173,DB0906810016256_,0.221788004,0.121939988,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,vortioxetine,DB09068
,107265,DB09068,10041349,38,2357,14,972,0.877860619,1.119301069,0.589647767,2.246958681,0.948282841,DB0906810041349_,0.053102466,0.112704445,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,vortioxetine,DB09068
,107268,DB00512,10017955,25,4712,42,5056,0.085655768,0.638724692,0.372403225,1.074523879,0.187762643,DB0051210017955_,1.672576651,-0.44828176,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,vancomycin,DB00512
,107269,DB01068,10017955,44,13719,30,6810,0.215694037,0.728026889,0.447051054,1.200550598,0.368258111,DB0106810017955_,0.998971197,-0.317417297,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,107282,DB00480,10017944,371,67057,318,67344,0.039176454,1.171657348,1.005546468,1.365831759,0.103973455,DB0048010017944_,2.263619655,0.158419283,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,107285,DB00218,10013700,267,1175,43,907,3.75078783853546e-26,4.790194281,3.41689526,6.85285833,6.23983913518384e-24,DB0021810013700_,53.43108783,1.56657097,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,moxifloxacin,DB00218
,107291,DB06674,10033371,149,4357,39,1451,0.198969811,1.27227308,0.884102875,1.869267618,0.347818161,DB0667410033371_,1.056075462,0.240805128,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,golimumab,DB06674
,107301,DB00363,10039897,68,4560,50,6838,0.000141047,2.039306491,1.391862876,3.005748266,0.001069964,DB0036310039897_,6.840130721,0.712609795,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,clozapine,DB00363
,107307,DB01068,10046555,31,13732,19,6821,0.456499981,0.810468952,0.443213628,1.519569107,0.623864715,DB0106810046555_,0.471821737,-0.210142246,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,clonazepam,DB01068
,107311,DB01068,10061284,68,13695,27,6813,0.382359847,1.252862754,0.790603418,2.037864762,0.552455576,DB0106810061284_,0.593382253,0.225431136,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,107321,DB01285,10016807,34,1242,20,589,0.462200975,0.806315425,0.446561335,1.491891073,0.629414186,DB0128510016807_,0.462965756,-0.215280267,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,corticotropin,DB01285
,107324,DB00758,10010774,129,8171,171,9903,0.482845117,0.914268553,0.720352186,1.158169445,0.647067599,DB0075810010774_,0.435304509,-0.089630929,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,107325,DB06285,10010774,133,8717,8,1098,0.041552241,2.09397772,1.028542544,4.964610452,0.108849975,DB0628510010774_,2.217784725,0.739065473,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,teriparatide,DB06285
,107327,DB00421,10013786,40,8863,17,5235,0.274742338,1.389752044,0.769305837,2.617195184,0.437964846,DB0042110013786_,0.825616633,0.329125346,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,spironolactone,DB00421
,107329,DB00761,10013786,85,15222,36,8589,0.155538904,1.332239484,0.891409779,2.027618587,0.291497124,DB0076110013786_,1.23272514,0.286861349,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,potassium chloride,DB00761
,107343,DB01394,10013709,55,1385,86,1917,0.541917503,0.885247371,0.614763401,1.265732249,0.697224746,DB0139410013709_,0.360647473,-0.121888158,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,colchicine,DB01394
,107345,DB00273,10041349,179,8302,46,2147,1,1.006339293,0.721456188,1.428572367,1,DB0027310041349_,0,0.006319284,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,107347,DB01225,10016173,137,4907,99,4541,0.06495882,1.280586588,0.97835189,1.681119546,0.152382202,DB0122510016173_,1.881363429,0.247318245,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,enoxaparin,DB01225
,107354,DB00264,10022093,96,29511,25,24867,1.26307085233301e-08,3.235534573,2.065176051,5.247754257,2.77822739360444e-07,DB0026410022093_,15.09628255,1.174194161,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,107355,DB00338,10022093,135,33539,19,22253,7.27149981897222e-14,4.714204726,2.903819467,8.07530152,3.79982848393012e-12,DB0033810022093_,26.29606519,1.550580233,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,107356,DB00404,10022093,82,19810,6,9856,4.92535438171994e-09,6.799606243,2.991725439,19.06921153,1.18447337532945e-07,DB0040410022093_,15.94879738,1.916864705,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,107369,DB00404,10007617,514,19378,403,9459,5.00019956956578e-12,0.622575357,0.54410592,0.71275849,2.02356036468109e-10,DB0040410007617_,22.32099241,-0.473890602,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,alprazolam,DB00404
,107370,DB00758,10007617,23,8277,34,10040,0.506771769,0.820568044,0.461103546,1.435540617,0.667443114,DB0075810007617_,0.404301115,-0.197758442,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,107372,DB01118,10007617,25,3038,42,4667,0.802161223,0.914406001,0.532867282,1.539192666,0.892951095,DB0111810007617_,0.113223464,-0.089480604,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,amiodarone,DB01118
,107376,DB01390,10021097,65,1344,51,1466,0.08823462,1.390036361,0.940972848,2.062824679,0.192309037,DB0139010021097_,1.648651632,0.329329906,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sodium bicarbonate,DB01390
,107379,DB00363,10029282,27,4601,56,6832,0.17753782,0.715951762,0.434116805,1.154622537,0.320694197,DB0036310029282_,1.137267267,-0.334142486,NA,10029282,Neuroleptic malignant syndrome,10029205,Nervous system disorders,Nerv,clozapine,DB00363
,107391,DB00624,10011906,7,555,81,4315,0.39632734,0.671940958,0.260498865,1.458666524,0.565971004,DB0062410011906_,0.569212431,-0.397584802,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,testosterone,DB00624
,107394,DB00335,10007739,45,8421,13,5452,0.009835034,2.240976676,1.18667995,4.532342425,0.035100321,DB0033510007739_,3.349544994,0.806911787,NA,10007739,Cataract,10015919,Eye disorders,Eye,atenolol,DB00335
,107395,DB01098,10007739,39,8110,19,7190,0.034478275,1.819706263,1.025458797,3.337121986,0.094372743,DB0109810007739_,2.360502986,0.598675094,NA,10007739,Cataract,10015919,Eye disorders,Eye,rosuvastatin,DB01098
,107401,DB05676,10013968,281,46848,175,25154,0.126871449,0.862161352,0.71086154,1.047971711,0.251276498,DB0567610013968_,1.38120136,-0.148312842,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,107410,DB00787,10007554,27,16973,46,17202,0.034567669,0.594888036,0.355432364,0.977785926,0.094563271,DB0078710007554_,2.358486137,-0.519382065,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,acyclovir,DB00787
,107415,DB00193,10013710,190,19130,98,8604,0.276847744,0.872006286,0.678873276,1.125940536,0.440319666,DB0019310013710_,0.820254302,-0.136958647,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,107416,DB00246,10013710,23,1051,39,662,0.000175488,0.371678692,0.209880659,0.644612532,0.001292073,DB0024610013710_,6.651507213,-0.98972553,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ziprasidone,DB00246
,107428,DB00480,10005555,82,67346,72,67590,0.42097618,1.143013268,0.822501862,1.591414936,0.589995142,DB0048010005555_,0.527640975,0.133667993,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,107430,DB01234,10005555,38,31587,34,32854,0.556595057,1.162473561,0.712272858,1.904132027,0.709923488,DB0123410005555_,0.342598079,0.150550115,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,107435,DB00928,10013709,27,808,49,1237,0.550506893,0.843665458,0.502604317,1.389378958,0.704654224,DB0092810013709_,0.350048059,-0.169999239,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,azacitidine,DB00928
,107441,DB01234,10022004,66,31559,64,32824,0.725746165,1.072552993,0.748592564,1.53761212,0.839364542,DB0123410022004_,0.175110172,0.070041782,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,107443,DB00928,10028813,38,797,23,1263,0.000278664,2.616969171,1.506725647,4.637565965,0.001901233,DB0092810028813_,6.265252465,0.962016843,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,azacitidine,DB00928
,107453,DB00584,10013709,89,1992,74,1800,0.631279392,1.086724477,0.783907859,1.510297428,0.770110172,DB0058410013709_,0.261221694,0.083168105,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,enalapril,DB00584
,107456,DB00115,10054236,69,18356,36,10436,0.760441991,1.089695843,0.717567783,1.68014478,0.86688573,DB0011510054236_,0.14284811,0.085898614,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,107457,DB00158,10054236,46,16769,38,8066,0.014353761,0.58227217,0.370328882,0.920445351,0.047553392,DB0015810054236_,3.045902149,-0.540817294,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,folic acid,DB00158
,107460,DB00736,10054236,43,10548,23,5530,1,0.980146724,0.576993424,1.705706841,1,DB0073610054236_,0,-0.020053,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,107462,DB01222,10054236,52,9222,16,5389,0.023118452,1.899104408,1.066068184,3.56737788,0.069190834,DB0122210054236_,2.670886884,0.641382411,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,budesonide,DB01222
,107485,DB00215,10000060,62,11041,13,5263,0.005990669,2.273290401,1.235648512,4.51071124,0.023634482,DB0021510000060_,3.745048543,0.821228298,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,107488,DB08827,10000060,42,1120,15,567,0.317285447,1.41723304,0.762161129,2.776114342,0.48510051,DB0882710000060_,0.723399172,0.348706407,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,lomitapide,DB08827
,107490,DB01217,10012735,209,2545,10,258,0.01842578,2.118331939,1.11009299,4.540525484,0.05791589,DB0121710012735_,2.84876349,0.750628958,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,anastrozole,DB01217
,107493,DB01098,10016766,47,8102,48,7161,0.536396206,0.865451505,0.565587917,1.323611819,0.69269796,DB0109810016766_,0.367161219,-0.144503937,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,107497,DB00227,10025482,84,2383,29,1774,0.000315178,2.155927468,1.391400674,3.427247955,0.002101586,DB0022710025482_,6.165062879,0.768221011,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,lovastatin,DB00227
,107498,DB00227,10047700,87,2380,18,1785,3.65148977521248e-08,3.624029065,2.154428934,6.423490941,7.24646347613892e-07,DB0022710047700_,14.1375821,1.287586408,female,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lovastatin,DB00227
,107507,DB00264,10028836,117,29490,77,24815,0.097107627,1.27859263,0.950407947,1.728448942,0.206460728,DB0026410028836_,1.577645062,0.245759965,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,107508,DB00421,10028836,50,8853,11,5241,0.001975841,2.690749708,1.381124689,5.736903539,0.009634867,DB0042110028836_,4.642366772,0.989819857,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,spironolactone,DB00421
,107511,DB05676,10053762,223,46906,103,25226,0.221504615,1.164341843,0.917353067,1.486047433,0.375374455,DB0567610053762_,0.979831204,0.152155986,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,apremilast,DB05676
,107514,DB01050,10014020,48,18060,6,9365,0.000149113,4.147901081,1.77181403,11.86599923,0.001120477,DB0105010014020_,6.794001216,1.422602443,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,ibuprofen,DB01050
,107515,DB00331,10028810,311,24635,127,20625,1.76716750654545e-12,2.050137625,1.661129363,2.542749046,7.62100047736624e-11,DB0033110028810_,23.29752837,0.717906925,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,metformin,DB00331
,107517,DB00715,10040753,60,4783,12,2275,0.004839994,2.377974573,1.263099903,4.866064419,0.019946573,DB0071510040753_,3.91469792,0.866249106,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,paroxetine,DB00715
,107518,DB08868,10003591,50,9152,17,2494,0.45487595,0.801512515,0.453482991,1.48514991,0.622442055,DB0886810003591_,0.474104739,-0.221254692,NA,10003591,Ataxia,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,107522,DB08868,10049848,212,8990,75,2436,0.057949294,0.765954397,0.583585058,1.014461802,0.139614774,DB0886810049848_,1.968868262,-0.266632645,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,107525,DB08895,10058080,78,28036,19,6627,0.897202661,0.970378387,0.581426714,1.69846405,0.956338178,DB0889510058080_,0.044643686,-0.030069194,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,107536,DB01039,10012735,212,2761,168,2883,0.010872539,1.317598207,1.063609157,1.634293416,0.03805642,DB0103910012735_,3.268685473,0.275810539,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fenofibrate,DB01039
,107537,DB09401,10012735,38,722,45,715,0.498407398,0.83635688,0.521527926,1.335107106,0.660264011,DB0940110012735_,0.415115508,-0.178699867,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,isosorbide,DB09401
,107538,DB00973,10028813,254,3597,102,2919,1.25436050478809e-09,2.020579446,1.590876467,2.581688995,3.42376592610124e-08,DB0097310028813_,17.18993965,0.703384325,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ezetimibe,DB00973
,107546,DB00165,10002034,54,2091,22,1344,0.075149841,1.577476164,0.93962456,2.733567613,0.170095028,DB0016510002034_,1.771398007,0.455826205,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,pyridoxine,DB00165
,107548,DB00555,10002034,39,7008,23,3463,0.500800803,0.837932739,0.487262985,1.472081883,0.662303985,DB0055510002034_,0.412030636,-0.176817446,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,lamotrigine,DB00555
,107549,DB00572,10002034,62,2840,52,2074,0.5023756,0.870746837,0.589805907,1.289965377,0.663631654,DB0057210002034_,0.410028021,-0.138404002,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,atropine,DB00572
,107655,DB00999,10018867,22,21408,49,12190,3.27972094451109e-08,0.255669841,0.147126045,0.431122048,6.57069093189589e-07,DB0099910018867_,14.23547666,-1.36386835,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,hydrochlorothiazide,DB00999
,107663,DB00544,10021027,32,2403,19,2634,0.034851009,1.845877313,1.01184974,3.456653296,0.095140341,DB0054410021027_,2.352402208,0.612954673,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,fluorouracil,DB00544
,107668,DB00999,10021027,32,21398,19,12220,0.885091366,0.961848453,0.528570836,1.796767801,0.952141547,DB0099910021027_,0.049041572,-0.038898374,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,107674,DB00581,10021097,45,2068,51,2018,0.472239768,0.861051134,0.560793342,1.318176636,0.63827868,DB0058110021097_,0.448980289,-0.149601387,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,lactulose,DB00581
,107686,DB00999,10024264,90,21340,62,12177,0.272013913,0.828331399,0.592299268,1.16484572,0.434881437,DB0099910024264_,0.832681843,-0.188341964,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,107691,DB00165,10035528,30,2115,29,1337,0.107684974,0.654052675,0.377395677,1.134925651,0.222683772,DB0016510035528_,1.502002576,-0.424567388,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,pyridoxine,DB00165
,107693,DB00572,10035528,44,2858,33,2093,0.908127867,0.976436555,0.605354417,1.588821198,0.958948296,DB0057210035528_,0.04191812,-0.023845503,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,atropine,DB00572
,107694,DB00727,10035528,33,3810,52,4121,0.101581755,0.686451424,0.428808044,1.084852011,0.213277849,DB0072710035528_,1.54515951,-0.376219815,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,nitroglycerin,DB00727
,107699,DB00398,10037660,20,707,55,1483,0.378499567,0.762827067,0.429579638,1.305082858,0.548524389,DB0039810037660_,0.600523535,-0.270723922,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sorafenib,DB00398
,107701,DB01175,10037660,192,10532,100,4792,0.279373733,0.873605178,0.680755852,1.126711338,0.443197452,DB0117510037660_,0.813739893,-0.135126747,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,107706,DB00581,10046571,52,2061,35,2034,0.08394229,1.466110844,0.932527888,2.32972446,0.18498461,DB0058110046571_,1.687482645,0.382613211,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,lactulose,DB00581
,107707,DB00727,10046571,98,3745,37,4136,5.36204992807187e-09,2.92481507,1.979195181,4.404605962,1.27896081995798e-07,DB0072710046571_,15.87204776,1.073231255,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,nitroglycerin,DB00727
,107719,DB00581,10048294,27,2086,44,2025,0.041213329,0.595769037,0.353279394,0.987989181,0.108129195,DB0058110048294_,2.224428517,-0.517902209,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,lactulose,DB00581
,107720,DB00646,10048294,24,3429,32,1968,0.001962329,0.43051233,0.241914817,0.756675897,0.009584654,DB0064610048294_,4.647592013,-0.842779313,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,nystatin,DB00646
,107759,DB01104,10013990,34,15429,17,7269,0.880793415,0.942255025,0.511605732,1.799699398,0.950123172,DB0110410013990_,0.051163648,-0.059479314,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,sertraline,DB01104
,107770,DB00451,10046555,59,47212,49,15370,2.81963076148755e-06,0.391998744,0.263675586,0.585000239,3.58818661659164e-05,DB0045110046555_,10.23527851,-0.936496644,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,107792,DB00136,10002034,38,2054,54,1628,0.00761597,0.557851695,0.356447707,0.86536009,0.028636831,DB0013610002034_,3.553061606,-0.583662131,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,calcitriol,DB00136
,107793,DB00410,10002034,44,1561,19,990,0.190503143,1.468488118,0.834059685,2.679641156,0.337185534,DB0041010002034_,1.087121954,0.38423338,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,mupirocin,DB00410
,107794,DB00410,10016256,138,1467,58,951,0.007475981,1.542170797,1.113813477,2.157392361,0.028219451,DB0041010016256_,3.567743781,0.433191032,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,mupirocin,DB00410
,107795,DB00658,10016256,46,1257,39,1357,0.320962107,1.273202023,0.806844441,2.017987764,0.489213626,DB0065810016256_,0.714956023,0.241535005,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sevelamer,DB00658
,107853,DB00213,10043414,35,18860,23,13398,0.791706378,1.081045673,0.620636628,1.917195331,0.887231487,DB0021310043414_,0.119649354,0.077928789,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,107854,DB00381,10043414,47,29313,33,22854,0.735381276,1.110451197,0.696278585,1.789655686,0.847122629,DB0038110043414_,0.165909814,0.104766417,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,107857,DB01076,10043414,51,25696,43,25540,0.470298144,1.178841014,0.769871673,1.812627725,0.636549264,DB0107610043414_,0.451693465,0.164531764,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,107900,DB00177,10040047,40,4760,36,2814,0.073761177,0.656926587,0.407125715,1.063364037,0.167811706,DB0017710040047_,1.784912728,-0.420183006,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,valsartan,DB00177
,107903,DB01050,10040047,111,17997,81,9290,0.021652919,0.707363815,0.525838703,0.955090323,0.065846686,DB0105010040047_,2.720426181,-0.346210155,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,107909,DB00656,10009033,68,11945,37,6582,1,1.012695117,0.668093777,1.55671998,1,DB0065610009033_,0,0.01261521,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,107910,DB00924,10009033,49,10113,24,4227,0.521645367,0.853394427,0.512856547,1.45623446,0.680376182,DB0092410009033_,0.385109425,-0.158533438,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,107912,DB13867,10009033,59,4491,26,2528,0.362964279,1.27733709,0.79028091,2.11699068,0.532469155,DB1386710009033_,0.630230308,0.244777512,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,107914,DB00868,10013968,210,2774,83,1563,0.007996849,1.425482754,1.091640901,1.87514193,0.029774378,DB0086810013968_,3.514107064,0.354510531,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,benzonatate,DB00868
,107917,DB01224,10003549,129,7979,110,5807,0.234714408,0.853506532,0.655108856,1.113590551,0.391587954,DB0122410003549_,0.937545129,-0.158402084,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,107918,DB01048,10016256,14,451,51,1084,0.20932546,0.659953738,0.333844551,1.225427632,0.360369381,DB0104810016256_,1.020625715,-0.415585541,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,abacavir,DB01048
,107920,DB00193,10020100,54,19266,27,8675,0.63283157,0.900558309,0.557004942,1.48803612,0.771556093,DB0019310020100_,0.259345903,-0.104740364,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,107933,DB00112,10005169,32,5901,22,4069,1,1.00297303,0.564054958,1.814500336,1,DB0011210005169_,0,0.002968619,NA,10005169,Blindness,10015919,Eye disorders,Eye,bevacizumab,DB00112
,107941,DB06403,10048669,34,21437,18,6643,0.07207897,0.585351252,0.321175427,1.101670556,0.164912366,DB0640310048669_,1.802341062,-0.535543181,NA,10048669,Terminal state,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,107946,DB00207,10028810,181,8899,85,5370,0.063680623,1.284925601,0.985319709,1.686800489,0.150093721,DB0020710028810_,1.896495375,0.250700819,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,azithromycin,DB00207
,107947,DB01060,10028810,154,8433,64,5017,0.016233013,1.431501518,1.06046652,1.951484159,0.052431156,DB0106010028810_,2.948254291,0.358723906,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,107953,DB00207,10043882,40,9040,19,5436,0.422460624,1.265946179,0.715392478,2.316834243,0.591507884,DB0020710043882_,0.525080267,0.23581981,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,azithromycin,DB00207
,107956,DB01060,10043882,39,8548,11,5070,0.027503943,2.102779556,1.054988036,4.556812824,0.079106176,DB0106010043882_,2.536964333,0.743260068,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,amoxicillin,DB01060
,107970,DB06605,10037884,53,14020,30,13003,0.035988072,1.638477851,1.027269359,2.657854859,0.097500151,DB0660510037884_,2.327901351,0.493767671,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,apixaban,DB06605
,107972,DB00264,10056342,50,29557,37,24855,0.591260157,1.136359104,0.727879043,1.788620938,0.737656337,DB0026410056342_,0.304277231,0.127829383,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,107974,DB00451,10056342,84,47187,29,15390,0.826886155,0.944703808,0.612536088,1.49556452,0.908717392,DB0045110056342_,0.095721133,-0.056883831,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,107977,DB00999,10056342,41,21389,16,12223,0.216393329,1.464355347,0.803703397,2.796654788,0.369116366,DB0099910056342_,0.99664333,0.38141511,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,107982,DB00682,10014011,55,19404,19,16345,0.000604846,2.438258496,1.423987471,4.352573966,0.003623148,DB0068210014011_,5.620411946,0.891284054,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,107983,DB01240,10014011,58,5693,6,1570,0.014288509,2.665645127,1.150255841,7.576538391,0.047367065,DB0124010014011_,3.049828133,0.980446102,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,107984,DB00203,10054236,96,13782,21,8917,8.9163676852306e-07,2.957587476,1.828472125,4.998719096,1.2957370957756e-05,DB0020310054236_,11.25384575,1.084373894,female,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,107985,DB00559,10054236,54,9605,20,3286,0.789158428,0.923704542,0.542971019,1.631760328,0.885744089,DB0055910054236_,0.121327208,-0.079363018,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,bosentan,DB00559
,107986,DB01240,10054236,87,5664,10,1566,0.005796419,2.405250685,1.243459429,5.204914958,0.023035815,DB0124010054236_,3.770705094,0.877654133,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,108010,DB00588,10021143,121,16403,73,8395,0.286401458,0.848335836,0.628484839,1.151811556,0.451144351,DB0058810021143_,0.795967922,-0.164478689,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,108011,DB01050,10021143,76,18032,37,9334,0.842483756,1.06324753,0.708158558,1.621853838,0.919801687,DB0105010021143_,0.08359719,0.061327932,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,108018,DB00471,10038687,42,14147,24,5441,0.130152835,0.6730727,0.397882252,1.16321798,0.255924239,DB0047110038687_,1.362873818,-0.395901932,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,108021,DB00381,10033775,296,29064,138,22749,3.03348741551472e-07,1.678860277,1.366115271,2.071564892,4.93716512178355e-06,DB0038110033775_,12.21871925,0.518115157,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,108022,DB00571,10033775,44,5079,14,2595,0.12737109,1.605681344,0.861708028,3.17867917,0.251924369,DB0057110033775_,1.378626359,0.47354818,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,propranolol,DB00571
,108037,DB05679,10003246,33,6898,26,4883,0.692867257,0.898480602,0.520412978,1.566435668,0.814954759,DB0567910003246_,0.204622678,-0.107050163,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ustekinumab,DB05679
,108042,DB00051,10009033,78,25653,43,11377,0.277473219,0.804511516,0.547129968,1.196911652,0.441060931,DB0005110009033_,0.818572247,-0.217519998,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,108044,DB05679,10011224,57,6874,28,4881,0.122063819,1.445448745,0.902765278,2.363962648,0.24439618,DB0567910011224_,1.408964681,0.368419824,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ustekinumab,DB05679
,108046,DB00051,10023215,37,25694,15,11405,0.880758036,1.094894427,0.586313742,2.148287408,0.950123172,DB0005110023215_,0.051163648,0.090657945,NA,10023215,Joint effusion,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,108053,DB05679,10028810,73,6858,33,4876,0.037052851,1.572745992,1.027266319,2.454150776,0.099701509,DB0567910028810_,2.305574464,0.452823131,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ustekinumab,DB05679
,108054,DB00065,10020751,162,9302,46,4911,0.000123192,1.859233133,1.329925042,2.644113279,0.000953225,DB0006510020751_,6.955659767,0.620164108,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,infliximab,DB00065
,108057,DB00158,10046735,143,16672,33,8071,4.9351591939545e-05,2.097734404,1.42689278,3.166130405,0.00043677,DB0015810046735_,7.736104053,0.740857907,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,108067,DB00480,10005191,162,67266,122,67540,0.017396664,1.333270411,1.047336242,1.700937536,0.055399966,DB0048010005191_,2.893176301,0.287634879,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,108071,DB00758,10043607,76,8224,82,9992,0.470738613,1.126070987,0.812030323,1.559987986,0.636965043,DB0075810043607_,0.451040502,0.118734571,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,clopidogrel,DB00758
,108100,DB00682,10002948,45,19414,33,16331,0.571358581,1.147076626,0.715471579,1.856549811,0.72156175,DB0068210002948_,0.326337319,0.137216642,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,108102,DB00285,10010305,140,10811,62,3656,0.086897077,0.763633926,0.560959705,1.049707514,0.18986614,DB0028510010305_,1.661435982,-0.269666759,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,108104,DB00437,10017577,92,6829,104,11442,0.007419837,1.482087781,1.1053907,1.984607757,0.028049821,DB0043710017577_,3.573773011,0.393451757,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,108105,DB01591,10017577,62,1893,11,645,0.054180581,1.920129802,0.994579159,4.069080741,0.132799008,DB0159110017577_,2.018918508,0.652392789,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,solifenacin,DB01591
,108106,DB00437,10027175,60,6861,69,11477,0.035859937,1.454518183,1.01031184,2.08912596,0.097253245,DB0043710027175_,2.330436925,0.3746747,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,108107,DB01591,10027175,41,1914,10,646,0.417721773,1.383616971,0.676730387,3.115710744,0.586748079,DB0159110027175_,0.533159718,0.324701064,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,solifenacin,DB01591
,108117,DB01202,10003658,36,6678,35,5683,0.633366571,0.875328203,0.533431579,1.437766867,0.771991699,DB0120210003658_,0.258781481,-0.133156373,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,levetiracetam,DB01202
,108122,DB00264,10029354,196,29411,200,24692,0.054425561,0.822764475,0.67164233,1.007738294,0.133306237,DB0026410029354_,2.015106264,-0.195085297,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,metoprolol,DB00264
,108124,DB00682,10029354,87,19372,102,16262,0.023190247,0.7160221,0.531211276,0.963371166,0.069326772,DB0068210029354_,2.668924129,-0.334044246,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,warfarin,DB00682
,108125,DB01050,10029354,116,17992,62,9309,0.873998135,0.968003922,0.704418014,1.341256087,0.94529538,DB0105010029354_,0.056257829,-0.03251914,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,ibuprofen,DB01050
,108133,DB00331,10043554,100,24846,133,20619,0.00035655,0.623978497,0.476163815,0.815457338,0.002329292,DB0033110043554_,6.06219072,-0.471639371,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,metformin,DB00331
,108134,DB01306,10043554,23,4185,34,3832,0.083758462,0.619453008,0.347732694,1.084923224,0.184689499,DB0130610043554_,1.689079247,-0.478918436,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,insulin aspart,DB01306
,108138,DB05676,10020937,114,47015,48,25281,0.161580468,1.277122251,0.903593422,1.829407886,0.299585616,DB0567610020937_,1.205355038,0.244609306,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,108149,DB00987,10025482,26,2078,30,2898,0.497991792,1.208609481,0.684368052,2.121279732,0.660081963,DB0098710025482_,0.415391266,0.18947051,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,cytarabine,DB00987
,108150,DB00059,10028813,43,784,97,1010,0.003297258,0.571245887,0.384509116,0.837138663,0.014605395,DB0005910028813_,4.226364269,-0.559935537,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pegaspargase,DB00059
,108151,DB00059,10043071,55,772,47,1060,0.023334611,1.606330983,1.055872137,2.452030592,0.069647448,DB0005910043071_,2.664309215,0.473952686,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,pegaspargase,DB00059
,108161,DB00563,10063743,56,46590,49,15299,1.16422912531722e-06,0.375292942,0.251067601,0.562623626,1.63864859753483e-05,DB0056310063743_,11.01905359,-0.980048379,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,108170,DB01068,10001949,118,13645,52,6788,0.513254793,1.128864538,0.806889031,1.598195114,0.673249107,DB0106810001949_,0.395639874,0.121212294,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,108172,DB01224,10016322,128,7980,70,5847,0.050601738,1.339778295,0.9913936,1.823249257,0.126102553,DB0122410016322_,2.070659793,0.292504149,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,108173,DB01068,10047513,160,13603,49,6791,0.002401817,1.630097042,1.175213385,2.296508945,0.011298748,DB0106810047513_,4.483063324,0.488639548,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,clonazepam,DB01068
,108174,DB01224,10047513,41,8067,15,5902,0.020789573,1.999663458,1.082425816,3.893300235,0.063722691,DB0122410047513_,2.753214568,0.692978895,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,quetiapine,DB01224
,108176,DB01104,10057668,50,15413,35,7251,0.08022365,0.672069097,0.427291961,1.067648708,0.178777332,DB0110410057668_,1.721614201,-0.397394121,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,108177,DB01224,10057668,56,8052,46,5871,0.547981288,0.887652475,0.589305939,1.342918612,0.70253326,DB0122410057668_,0.353062533,-0.11917497,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,108184,DB00951,10016256,32,620,21,544,0.327622213,1.336702466,0.737384166,2.470318452,0.496085596,DB0095110016256_,0.701006794,0.290205735,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,isoniazid,DB00951
,108200,DB06724,10013709,227,7702,77,3842,0.003633567,1.470536272,1.127290463,1.935697757,0.01579041,DB0672410013709_,4.148352473,0.385627145,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,108202,DB06724,10013710,53,7876,35,3884,0.210500408,0.746750231,0.47737324,1.181383216,0.361799727,DB0672410013710_,1.016664462,-0.292024513,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,108215,DB00472,10029216,42,10717,12,4300,0.365837581,1.4042297,0.724927247,2.933185364,0.535414299,DB0047210029216_,0.624714441,0.339488896,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,108219,DB00331,10018867,46,24900,82,20670,2.48556578184948e-05,0.465681484,0.317116715,0.67656516,0.000240372,DB0033110018867_,8.333323034,-0.764253388,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,108222,DB14500,10010264,159,7650,65,4008,0.102091998,1.281600854,0.951963673,1.742185948,0.214096711,DB1450010010264_,1.541327444,0.248109964,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,108225,DB00264,10011781,124,29483,43,24849,1.32262329938616e-07,2.43036082,1.704597781,3.524531975,2.34345489884497e-06,DB0026410011781_,12.96388426,0.888039732,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,metoprolol,DB00264
,108226,DB00381,10011781,119,29241,26,22861,6.54373906759393e-11,3.578158438,2.324594895,5.702565468,2.20515617168855e-09,DB0038110011781_,19.9324675,1.274848265,female,10011781,Cystitis,10021881,Infections and infestations,Infec,amlodipine,DB00381
,108227,DB00471,10011781,57,14132,6,5459,0.000603885,3.669764683,1.584675205,10.42283011,0.003617803,DB0047110011781_,5.621888462,1.300127541,female,10011781,Cystitis,10021881,Infections and infestations,Infec,montelukast,DB00471
,108229,DB00695,10011781,118,27931,36,20492,1.10176747193875e-06,2.404724385,1.642487161,3.59835048,1.55866297093165e-05,DB0069510011781_,11.06909708,0.877435296,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,furosemide,DB00695
,108231,DB14500,10011781,42,7767,9,4064,0.011522828,2.441628486,1.170014605,5.711129135,0.039878543,DB1450010011781_,3.22191686,0.892665229,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,potassium,DB14500
,108232,DB00178,10013968,72,1365,74,1606,0.444729836,1.144706455,0.809028164,1.618948412,0.612797428,DB0017810013968_,0.489720858,0.135148233,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ramipril,DB00178
,108233,DB01129,10013968,47,865,13,423,0.089274872,1.767313637,0.928256391,3.600743223,0.19408544,DB0112910013968_,1.639456802,0.569460674,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rabeprazole,DB01129
,108247,DB08880,10033371,139,3199,35,774,0.845036903,0.960895166,0.653059438,1.447026911,0.921765987,DB0888010033371_,0.081463898,-0.039889964,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,teriflunomide,DB08880
,108249,DB00715,10002855,153,4690,55,2232,0.082898285,1.323869933,0.962439974,1.84383103,0.183223158,DB0071510002855_,1.697050424,0.280559214,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,paroxetine,DB00715
,108251,DB01020,10008190,32,1781,26,1852,0.358155147,1.279744787,0.73557452,2.24552195,0.527878861,DB0102010008190_,0.638888452,0.246660673,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,isosorbide mononitrate,DB01020
,108253,DB01020,10053762,38,1775,45,1833,0.579555444,0.872070412,0.548111738,1.381037537,0.728219076,DB0102010053762_,0.317153348,-0.136885111,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,isosorbide mononitrate,DB01020
,108254,DB00281,10013971,40,11418,19,5652,1,1.042115475,0.589024996,1.906922669,1,DB0028110013971_,0,0.041252758,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,108256,DB00787,10013971,28,16972,43,17205,0.096197233,0.660113522,0.394696271,1.087788381,0.205022644,DB0078710013971_,1.584634846,-0.415343455,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,108259,DB00588,10025197,40,16484,17,8451,0.577022416,1.20626932,0.668062895,2.27053524,0.726231208,DB0058810025197_,0.319886846,0.18753239,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,fluticasone propionate,DB00588
,108268,DB00338,10056342,72,33602,33,22239,0.089573969,1.443995153,0.94349109,2.25224512,0.19453456,DB0033810056342_,1.637145444,0.367413684,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,108285,DB00727,10040047,42,3801,60,4113,0.194645369,0.757486291,0.496844853,1.145529703,0.342556562,DB0072710040047_,1.07131849,-0.277749839,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,nitroglycerin,DB00727
,108308,DB00046,10040753,40,5419,13,4679,0.001358392,2.656407613,1.389874042,5.419673421,0.007087908,DB0004610040753_,4.94936501,0.976974689,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,insulin lispro,DB00046
,108309,DB01098,10040753,137,8012,38,7171,4.41804440292371e-12,3.226408644,2.23449732,4.759624112,1.79765165837229e-10,DB0109810040753_,22.43936975,1.171369644,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,rosuvastatin,DB01098
,108332,DB01224,10008531,36,8072,16,5901,0.120981071,1.644792779,0.888789308,3.177787483,0.242856904,DB0122410008531_,1.41528288,0.497614406,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,108335,DB00472,10042464,92,10667,49,4263,0.111543327,0.750359173,0.523933307,1.086142078,0.228351286,DB0047210042464_,1.476870106,-0.28720329,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,108338,DB00795,10003549,65,4504,25,1478,0.538197509,0.853246401,0.528208363,1.418237422,0.694154495,DB0079510003549_,0.365060728,-0.158706909,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,108343,DB04868,10019211,68,1573,47,1469,0.12843169,1.351020233,0.911230115,2.017534754,0.253421437,DB0486810019211_,1.372701416,0.300860035,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,nilotinib,DB04868
,108344,DB00590,10021097,32,744,67,1885,0.426850677,1.209954455,0.761438745,1.88801364,0.59554465,DB0059010021097_,0.518278914,0.190582719,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,doxazosin,DB00590
,108349,DB00381,10040560,139,29221,166,22721,0.00020374,0.651102676,0.515591203,0.821175261,0.001463397,DB0038110040560_,6.526994526,-0.429087928,NA,10040560,Shock,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,108355,DB00177,10070863,31,4769,29,2821,0.081776555,0.632390243,0.367832346,1.090053175,0.181346219,DB0017710070863_,1.707347262,-0.458248602,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,valsartan,DB00177
,108356,DB00335,10070863,141,8325,181,5284,6.39339868600101e-10,0.494463131,0.392838846,0.621441468,1.8406405746061e-08,DB0033510070863_,17.81056709,-0.704282689,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,atenolol,DB00335
,108357,DB00381,10070863,826,28534,739,22148,0.006097546,0.867580141,0.783430078,0.960907075,0.023976961,DB0038110070863_,3.730661861,-0.14204739,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,108367,DB00722,10005364,43,25360,42,25990,0.829157419,1.049260179,0.669413043,1.645723245,0.910242979,DB0072210005364_,0.094043705,0.048085324,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,lisinopril,DB00722
,108372,DB05351,10008479,46,2677,15,1116,0.479637077,1.278340389,0.697421219,2.475739486,0.644575927,DB0535110008479_,0.439162655,0.245562665,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,dexlansoprazole,DB05351
,108387,DB01016,10003549,36,1065,44,1184,0.732980339,0.909660224,0.564187217,1.458205932,0.845054091,DB0101610003549_,0.168354641,-0.094684129,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,glyburide,DB01016
,108389,DB00068,10044565,46,2188,17,648,0.449233283,0.801441267,0.447160793,1.501838746,0.616834119,DB0006810044565_,0.483155142,-0.221343588,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,interferon beta-1b,DB00068
,108398,DB00531,10021036,37,7215,51,6465,0.053403833,0.650101528,0.413318543,1.013804486,0.131379078,DB0053110021036_,2.029668406,-0.430626731,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,cyclophosphamide,DB00531
,108421,DB00177,10011906,127,4673,108,2742,0.006030394,0.690063467,0.527280107,0.904376861,0.02375733,DB0017710011906_,3.739864163,-0.370971705,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,108423,DB00374,10012378,114,17602,32,5692,0.561957407,1.152005081,0.77141968,1.764862317,0.714284699,DB0037410012378_,0.336473657,0.141503973,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,treprostinil,DB00374
,108424,DB00374,10017885,145,17571,35,5689,0.138275294,1.341309916,0.920673726,2.002411151,0.267345796,DB0037410017885_,1.319212342,0.293646686,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,108446,DB00287,10013709,60,1341,37,780,0.829707208,0.943250619,0.60959072,1.476343547,0.910667119,DB0028710013709_,0.09357785,-0.058423263,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,travoprost,DB00287
,108453,DB06403,10060933,61,21410,16,6645,0.686974114,1.183272084,0.673146696,2.200418329,0.811209353,DB0640310060933_,0.209229117,0.168283554,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,108454,DB00005,10003757,48,128034,17,42402,0.775638781,0.935083909,0.52808033,1.734706677,0.877792514,DB0000510003757_,0.13034503,-0.067119012,NA,10003757,Atypical pneumonia,10021881,Infections and infestations,Infec,etanercept,DB00005
,108461,DB08932,10028391,153,19290,60,6537,0.342806795,0.864170039,0.636208542,1.186758432,0.512130302,DB0893210028391_,0.66917619,-0.145985725,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,108462,DB00635,10064882,34,33019,16,23778,0.196478799,1.530264837,0.821688982,2.969720295,0.34471889,DB0063510064882_,1.065026007,0.425440816,NA,10064882,Procedural pain,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,108469,DB01273,10013573,40,2000,24,1251,0.897720854,1.042490634,0.609903936,1.81723304,0.956338178,DB0127310013573_,0.044643686,0.04161269,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,varenicline,DB01273
,108475,DB01222,10061822,47,9227,23,5382,0.536197809,1.191960589,0.708480452,2.059031795,0.692536584,DB0122210061822_,0.367394214,0.175599505,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,108477,DB01101,10021097,39,7550,32,3876,0.058676269,0.625686635,0.381295815,1.033513636,0.141023848,DB0110110021097_,1.958826265,-0.468905617,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,capecitabine,DB01101
,108482,DB08880,10020772,70,3268,9,800,0.083750071,1.903705633,0.942263258,4.354583593,0.184678743,DB0888010020772_,1.689137487,0.64380232,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,teriflunomide,DB08880
,108491,DB00682,10018276,33,19426,30,16334,0.800740598,0.924922932,0.546583056,1.570645407,0.892281272,DB0068210018276_,0.113973868,-0.078044862,NA,10018276,Gingival bleeding,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,108493,DB00472,10042128,43,10716,9,4303,0.089528918,1.918441406,0.921412439,4.479900176,0.194496921,DB0047210042128_,1.637338946,0.651513089,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,108494,DB00788,10042128,59,9297,19,5042,0.056236638,1.684007113,0.988445674,2.99483816,0.136527203,DB0078810042128_,1.991231397,0.52117614,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,108496,DB01060,10042128,49,8538,20,5061,0.17105464,1.452228473,0.846299911,2.582338018,0.312288328,DB0106010042128_,1.163828389,0.373099254,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,108502,DB00437,10037087,142,6779,142,11404,1.82970606306694e-05,1.682129752,1.320916205,2.142278428,0.000184586,DB0043710037087_,8.597396293,0.5200607,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,108503,DB09073,10037087,491,19769,10,780,0.032000114,1.937273347,1.038762152,4.081627394,0.089106731,DB0907310037087_,2.417920404,0.661281493,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,palbociclib,DB09073
,108504,DB00215,10043554,47,11056,52,5224,3.19371421695583e-05,0.427090596,0.281240161,0.647116565,0.000299917,DB0021510043554_,8.11200467,-0.85075912,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,citalopram,DB00215
,108506,DB09073,10043554,211,20049,11,779,0.370105485,0.745318679,0.405889581,1.522349113,0.539747838,DB0907310043554_,0.616653216,-0.293943395,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,palbociclib,DB09073
,108507,DB01224,10048959,72,8036,56,5861,0.720078062,0.937737805,0.651018127,1.356719424,0.834774158,DB0122410048959_,0.180594061,-0.064284894,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,108508,DB00331,10074903,159,24787,93,20659,0.006368486,1.424935933,1.095605895,1.862009942,0.024837994,DB0033110074903_,3.695380789,0.354126854,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,108514,DB01075,10005734,70,19878,45,11052,0.437654824,0.864885615,0.585900789,1.288245319,0.606098896,DB0107510005734_,0.500712111,-0.145158018,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,diphenhydramine,DB01075
,108521,DB00404,10031009,61,19831,17,9845,0.03979246,1.781329979,1.026361014,3.25523381,0.105273495,DB0040410031009_,2.251193597,0.577360264,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,108522,DB06643,10031009,102,52319,11,7504,0.475924567,1.329960914,0.712420489,2.749389365,0.641432955,DB0664310031009_,0.444050613,0.285149554,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,108526,DB01175,10061822,77,10647,27,4865,0.288549216,1.303048441,0.829647729,2.10468521,0.453592257,DB0117510061822_,0.790556597,0.264706474,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,108528,DB00019,10003549,165,18847,77,9452,0.632287344,1.074664734,0.814138038,1.42916122,0.770964088,DB0001910003549_,0.260113485,0.072008738,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,108529,DB00019,10012174,94,18918,33,9496,0.089167925,1.429796646,0.951599425,2.19699336,0.193909068,DB0001910012174_,1.640365951,0.357532229,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,pegfilgrastim,DB00019
,108533,DB01234,10018836,58,31567,67,32821,0.591572018,0.900069096,0.621946555,1.299147479,0.737872742,DB0123410018836_,0.303983906,-0.105283746,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,108536,DB06186,10021015,35,2174,20,3626,0.000117101,2.918261331,1.633874019,5.349591361,0.000913357,DB0618610021015_,6.998383851,1.070988004,female,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,ipilimumab,DB06186
,108538,DB00203,10005191,34,13844,21,8917,1,1.042839765,0.587663013,1.892239298,1,DB0020310005191_,0,0.041947535,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,sildenafil,DB00203
,108539,DB00374,10005191,49,17667,10,5714,0.224491314,1.584723384,0.79237217,3.511489064,0.379147632,DB0037410005191_,0.96982962,0.460409871,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,treprostinil,DB00374
,108541,DB00374,10012587,141,17575,36,5688,0.219602072,1.267574764,0.872517535,1.884833192,0.372972041,DB0037410012587_,0.986251819,0.23710544,NA,10012587,Device leakage,10077536,Product issues,Prod,treprostinil,DB00374
,108550,DB00182,10013710,43,5151,36,2816,0.07544189,0.652999802,0.408564827,1.049237982,0.17055045,DB0018210013710_,1.76872413,-0.426178453,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,108551,DB00776,10013710,32,1873,66,1273,1.79332951635458e-07,0.329644591,0.207757571,0.513578157,3.07486407941161e-06,DB0077610013710_,12.69224986,-1.109740201,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,oxcarbazepine,DB00776
,108590,DB00264,10039020,53,29554,99,24793,1.71635839127166e-06,0.449114421,0.31532922,0.633479308,2.31475014441127e-05,DB0026410039020_,10.67362371,-0.80047759,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,108591,DB00682,10039020,7,19452,46,16318,6.62277032871973e-10,0.127666256,0.048626753,0.284775006,1.90354858491414e-08,DB0068210039020_,17.77696092,-2.058335792,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,108593,DB00999,10039020,27,21403,53,12186,6.74980673829639e-08,0.290062155,0.175315087,0.469732434,1.26863546740165e-06,DB0099910039020_,13.57756867,-1.237660052,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,108596,DB00829,10008531,66,7986,20,4434,0.017250032,1.832150277,1.095159879,3.195425613,0.055023006,DB0082910008531_,2.900003892,0.605490292,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,108597,DB00169,10020028,55,38636,13,18162,0.026153417,1.988777473,1.07230138,3.969160549,0.076078194,DB0016910020028_,2.575993594,0.687520115,NA,10020028,Hiatus hernia,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,108598,DB00338,10020028,86,33588,25,22247,0.000137075,2.278441477,1.444654652,3.714505572,0.001043902,DB0033810020028_,6.864789644,0.823491646,NA,10020028,Hiatus hernia,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,108623,DB00374,10029331,54,17662,12,5712,0.314323841,1.455278566,0.768222586,2.991132421,0.481939863,DB0037410029331_,0.729935939,0.375197337,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,108626,DB00635,10005425,89,32964,23,23771,2.91596512182884e-06,2.790325743,1.747588402,4.626950962,3.69646217638153e-05,DB0063510005425_,10.20554927,1.026158343,female,10005425,Blood cholesterol increased,10022891,Investigations,Inv,prednisone,DB00635
,108627,DB00193,10039073,227,19093,35,8667,3.87189190817166e-11,2.944008751,2.053731173,4.335809722,1.35066594301648e-09,DB0019310039073_,20.42266808,1.079772173,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,108628,DB00285,10039073,61,10890,7,3711,0.003022448,2.969559526,1.355728589,7.702677184,0.013596617,DB0028510039073_,4.297934258,1.088413634,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,venlafaxine,DB00285
,108629,DB00338,10039073,238,33436,59,22213,2.81392385373724e-13,2.679821976,2.006595182,3.6290653,1.36586943152799e-11,DB0033810039073_,25.01664485,0.985750365,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,108630,DB00682,10039073,47,19412,18,16346,0.003864027,2.198605504,1.252517069,4.024521785,0.016582197,DB0068210039073_,4.099425623,0.787823298,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,108632,DB08895,10043607,89,28025,35,6611,0.015597772,0.599862768,0.401083986,0.915046966,0.05083224,DB0889510043607_,2.97922448,-0.51105437,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,tofacitinib,DB08895
,108649,DB01109,10013700,183,4229,114,4156,0.000151598,1.577462294,1.236601402,2.019185543,0.001137619,DB0110910013700_,6.778817901,0.455817412,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,heparin,DB01109
,108650,DB00472,10022086,99,10660,29,4283,0.141588565,1.371529717,0.897294705,2.155998285,0.272007703,DB0047210022086_,1.301924893,0.315926699,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,108653,DB00472,10064355,39,10720,22,4290,0.202644335,0.709438998,0.409798062,1.257830876,0.352119148,DB0047210064355_,1.043785673,-0.343280765,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,108659,DB01267,10001540,41,2811,74,3641,0.10628485,0.717685049,0.476095803,1.068809783,0.220618912,DB0126710001540_,1.511318446,-0.331724456,NA,10001540,Akathisia,10029205,Nervous system disorders,Nerv,paliperidone,DB01267
,108668,DB00213,10014011,43,18852,14,13407,0.010073042,2.184247455,1.171598519,4.32472209,0.035774882,DB0021310014011_,3.330509256,0.781271355,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,108672,DB00213,10019022,34,18861,21,13400,0.682190651,1.1502312,0.648333762,2.086618624,0.807817551,DB0021310019022_,0.213419049,0.139962965,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,108674,DB00213,10021114,36,18859,19,13402,0.338626599,1.346466846,0.751751522,2.486106709,0.507688806,DB0021310021114_,0.677886605,0.29748401,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,pantoprazole,DB00213
,108683,DB00451,10047626,70,47201,23,15396,1,0.992720315,0.611862283,1.667159009,1,DB0045110047626_,0,-0.007306312,NA,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,108686,DB00451,10048762,55,47216,16,15403,0.783298253,1.121392385,0.633035403,2.097350384,0.882057861,DB0045110048762_,0.125497624,0.114571114,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,108688,DB00213,10060945,40,18855,20,13401,0.237914682,1.421463532,0.811169811,2.567748595,0.39539627,DB0021310060945_,0.927866801,0.351686997,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,108693,DB00381,10012671,26,29334,40,22847,0.008618029,0.50627184,0.296547884,0.850523873,0.031610501,DB0038110012671_,3.454265914,-0.68068152,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,108695,DB00635,10012671,34,33019,35,23759,0.143804679,0.699013045,0.422841385,1.154399339,0.275232534,DB0063510012671_,1.290138962,-0.358085875,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,108702,DB00213,10012601,60,18835,37,13384,0.536769737,1.15227369,0.752010088,1.786848977,0.693029219,DB0021310012601_,0.366683118,0.141737112,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,108704,DB00264,10012601,103,29504,80,24812,0.603813757,1.082775952,0.800224648,1.469477605,0.747337482,DB0026410012601_,0.291238412,0.07952807,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,108716,DB06589,10012174,41,1989,40,2613,0.213295134,1.34646747,0.845952807,2.144734879,0.365405229,DB0658910012174_,1.006748324,0.297484474,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,pazopanib,DB06589
,108728,DB08896,10003988,43,780,37,1003,0.08468979,1.494071922,0.930175288,2.410137405,0.18624314,DB0889610003988_,1.680702257,0.401505226,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,regorafenib,DB08896
,108731,DB00374,10057925,50,17666,19,5705,0.574472068,0.849868932,0.491748445,1.527703878,0.724237911,DB0037410057925_,0.322635335,-0.162673139,NA,10057925,Transplant evaluation,10022891,Investigations,Inv,treprostinil,DB00374
,108772,DB01593,10035664,30,1103,21,677,0.662747529,0.876896612,0.481178053,1.625529194,0.794417715,DB0159310035664_,0.230145866,-0.131366182,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,zinc,DB01593
,108773,DB06186,10035664,65,2144,86,3560,0.174434139,1.254921724,0.890883068,1.760693719,0.316687027,DB0618610035664_,1.149841288,0.2270732,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ipilimumab,DB06186
,108774,DB09035,10035664,103,4623,190,6500,0.030402224,0.762225485,0.591951074,0.976937508,0.08554999,DB0903510035664_,2.458654395,-0.271512854,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,nivolumab,DB09035
,108782,DB00512,10035742,25,4712,30,5068,0.786984835,0.896311284,0.504646792,1.579156274,0.884476968,DB0051210035742_,0.122758806,-0.109467511,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vancomycin,DB00512
,108785,DB01075,10035742,39,19909,32,11065,0.107609826,0.677394796,0.413246486,1.117603342,0.222581966,DB0107510035742_,1.502459858,-0.389501021,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,108789,DB08896,10013573,40,783,29,1011,0.025505989,1.780357986,1.065854801,3.00689439,0.074624324,DB0889610013573_,2.595288772,0.57681446,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,regorafenib,DB08896
,108793,DB01202,10011224,63,6651,43,5675,0.282329772,1.250094488,0.833555089,1.89047001,0.446367357,DB0120210011224_,0.806612995,0.223219139,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levetiracetam,DB01202
,108796,DB00874,10028334,55,3280,35,1941,0.742395851,0.929935274,0.595409462,1.469738094,0.852376218,DB0087410028334_,0.15972728,-0.072640293,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,guaifenesin,DB00874
,108798,DB14512,10028334,61,4783,15,2397,0.013743115,2.037835448,1.141353392,3.86928852,0.045858682,DB1451210028334_,3.082190742,0.71188819,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,mometasone furoate,DB14512
,108799,DB00874,10036790,40,3295,19,1957,0.498863165,1.250293534,0.705109694,2.29254623,0.660768388,DB0087410036790_,0.414351896,0.223378351,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,guaifenesin,DB00874
,108803,DB00874,10046735,38,3297,16,1960,0.261656249,1.411802161,0.766250142,2.719636157,0.423291144,DB0087410046735_,0.859695054,0.344867016,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,guaifenesin,DB00874
,108804,DB00983,10046735,40,3461,14,1726,0.309564584,1.424766333,0.756389674,2.843279765,0.477006735,DB0098310046735_,0.740224669,0.354007823,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,formoterol,DB00983
,108805,DB01060,10046735,141,8446,75,5006,0.478404677,1.114297971,0.834246392,1.498279131,0.643710283,DB0106010046735_,0.440506526,0.108224584,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,amoxicillin,DB01060
,108806,DB01202,10046735,51,6663,25,5693,0.027628689,1.742936755,1.058625278,2.939613036,0.079416052,DB0120210046735_,2.533054765,0.555571481,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,levetiracetam,DB01202
,108818,DB00169,10057362,123,38568,56,18119,0.872837427,1.031899966,0.746063895,1.442563381,0.944495289,DB0016910057362_,0.05710458,0.031401731,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,108819,DB00338,10057362,85,33589,60,22212,0.734213322,0.9368261,0.664981575,1.326951432,0.846123032,DB0033810057362_,0.167090502,-0.065257607,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,108822,DB00999,10057362,49,21381,33,12206,0.490961194,0.847682679,0.533938661,1.361425017,0.654175241,DB0099910057362_,0.424380011,-0.165248913,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,108833,DB00060,10022000,97,9411,23,2442,0.820391141,1.094335508,0.687214584,1.811345998,0.90434181,DB0006010022000_,0.100547881,0.090147337,NA,10022000,Influenza,10021881,Infections and infestations,Infec,interferon beta-1a,DB00060
,108839,DB00216,10013709,111,812,17,91,0.279845513,0.731988054,0.413929357,1.361010788,0.443678105,DB0021610013709_,0.812655968,-0.311991084,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,eletriptan,DB00216
,108846,DB01261,10005554,37,3744,29,3274,0.710861126,1.115660939,0.666024698,1.885379417,0.827574838,DB0126110005554_,0.189255737,0.109447,NA,10005554,Blood glucose abnormal,10022891,Investigations,Inv,sitagliptin,DB01261
,108847,DB00374,10005555,44,17672,10,5714,0.346210766,1.422636465,0.704842626,3.172642626,0.515618448,DB0037410005555_,0.662388228,0.352511815,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,treprostinil,DB00374
,108860,DB00126,10048294,36,10135,27,5918,0.360077736,0.778583545,0.459152399,1.334869552,0.5299204,DB0012610048294_,0.635028473,-0.250278978,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,ascorbic acid,DB00126
,108861,DB00715,10022086,39,4804,16,2271,0.771944655,1.152250706,0.627674102,2.2135533,0.875159166,DB0071510022086_,0.133349505,0.141717165,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,108863,DB00051,10052904,305,25426,113,11307,0.109629347,1.20028173,0.963048321,1.504717539,0.225513177,DB0005110052904_,1.489376687,0.182556304,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,108873,DB00319,10008531,41,1351,30,1823,0.014741732,1.843748287,1.117032452,3.075004213,0.048645587,DB0031910008531_,3.023194183,0.611800612,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,piperacillin,DB00319
,108877,DB00678,10024570,32,15567,21,10703,1,1.047690138,0.585446808,1.912823425,1,DB0067810024570_,0,0.046587873,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,108878,DB00540,10002855,60,2423,21,1070,0.395199512,1.261608103,0.75183861,2.195420394,0.564978732,DB0054010002855_,0.570967192,0.23238718,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,nortriptyline,DB00540
,108879,DB06637,10002855,78,6084,15,2004,0.053589148,1.71264535,0.974745744,3.213069852,0.131724014,DB0663710002855_,2.027046348,0.538039164,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,dalfampridine,DB06637
,108881,DB00540,10003549,50,2433,32,1059,0.113934664,0.68017797,0.425101678,1.102315151,0.232062972,DB0054010003549_,1.460746514,-0.385400794,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,nortriptyline,DB00540
,108882,DB00745,10003549,75,2502,38,1045,0.346847518,0.824408217,0.54681464,1.260823437,0.516274252,DB0074510003549_,0.661117159,-0.193089463,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,modafinil,DB00745
,108899,DB06637,10012174,43,6119,13,2006,0.87744145,1.08435423,0.570943917,2.202631471,0.947946918,DB0663710012174_,0.053456772,0.08098463,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,dalfampridine,DB06637
,108901,DB00181,10012378,227,9629,90,5781,0.000807446,1.514237942,1.178398692,1.959467974,0.004611847,DB0018110012378_,5.379126937,0.414912304,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,108902,DB00540,10012378,48,2435,26,1065,0.374823648,0.807530699,0.488059128,1.363724044,0.544653635,DB0054010012378_,0.607605219,-0.213774207,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,nortriptyline,DB00540
,108903,DB06637,10012378,155,6007,44,1975,0.453691536,1.158189954,0.820350443,1.664467981,0.621237863,DB0663710012378_,0.476041238,0.146858402,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,dalfampridine,DB06637
,108909,DB00169,10028035,69,38622,23,18152,0.179118985,1.409990917,0.868108246,2.369812397,0.322807166,DB0016910028035_,1.130700144,0.343583262,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,108910,DB00181,10028035,34,9822,27,5844,0.289071711,0.749279504,0.43832202,1.292556128,0.454196301,DB0018110028035_,0.789225793,-0.288643196,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,108915,DB00996,10028035,69,38884,24,22401,0.031307484,1.656268599,1.027276239,2.757327325,0.087586315,DB0099610028035_,2.435130516,0.50456724,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,108920,DB00169,10028335,54,38637,34,18141,0.207744833,0.745694313,0.47656828,1.181717653,0.358587663,DB0016910028335_,1.025582123,-0.293439531,NA,10028335,Muscle spasticity,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,108926,DB06637,10028335,63,6099,25,1994,0.455381177,0.823886364,0.509327521,1.37081664,0.62285387,DB0663710028335_,0.473443347,-0.193722666,NA,10028335,Muscle spasticity,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,108928,DB00788,10028372,83,9273,47,5014,0.782816028,0.954881192,0.658636324,1.398719408,0.881806742,DB0078810028372_,0.12578236,-0.046168353,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,108929,DB01104,10028372,123,15340,76,7210,0.066910699,0.760660173,0.566070593,1.027786563,0.155765453,DB0110410028372_,1.859403907,-0.273568574,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,108932,DB00425,10039203,49,12646,36,7448,0.313453018,0.801661947,0.510282752,1.270225971,0.480975632,DB0042510039203_,0.73193867,-0.221068272,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,108936,DB01050,10039203,56,18052,22,9349,0.284834376,1.318288617,0.791543716,2.26872748,0.449365078,DB0105010039203_,0.79991963,0.276334393,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,108937,DB01104,10039203,38,15425,18,7268,1,0.994720175,0.553517763,1.852875243,1,DB0110410039203_,0,-0.005293813,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,108940,DB00540,10041349,42,2441,16,1075,0.669239748,1.155978871,0.633113819,2.212787299,0.79917165,DB0054010041349_,0.224179526,0.144947492,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,nortriptyline,DB00540
,108941,DB00788,10041349,123,9233,50,5011,0.092392908,1.335083233,0.951757365,1.897390229,0.199044962,DB0078810041349_,1.614224538,0.288993637,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,108942,DB06637,10041349,55,6107,13,2006,0.324888518,1.389629793,0.747585081,2.779027464,0.493335756,DB0663710041349_,0.70656529,0.329037376,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,108946,DB00169,10043431,54,38637,12,18163,0.016844771,2.115396043,1.117385659,4.345738834,0.054012176,DB0016910043431_,2.918545778,0.749242049,NA,10043431,Thinking abnormal,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,108949,DB00404,10043431,51,19841,24,9838,0.902594001,1.05366174,0.636300966,1.791124342,0.957195726,DB0040410043431_,0.043747388,0.052271469,NA,10043431,Thinking abnormal,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,108953,DB00996,10043431,48,38905,21,22404,0.319014421,1.316255479,0.7729295,2.314975475,0.487120603,DB0099610043431_,0.719243543,0.274790947,NA,10043431,Thinking abnormal,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,108973,DB00745,10044565,53,2524,13,1070,0.078064037,1.728102362,0.92457999,3.470529692,0.175130219,DB0074510044565_,1.742225473,0.547023906,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,modafinil,DB00745
,108975,DB00745,10048393,128,2449,29,1054,0.001664009,1.89931645,1.251931103,2.968461652,0.008364596,DB0074510048393_,4.783747263,0.641494059,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,modafinil,DB00745
,108976,DB00788,10048393,85,9271,18,5043,0.00010591,2.568524191,1.529543175,4.545259518,0.000838125,DB0078810048393_,7.084343065,0.943331489,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,108977,DB01104,10048393,133,15330,33,7253,0.000582089,1.906787705,1.29276464,2.886049166,0.003506006,DB0110410048393_,5.653277774,0.645419996,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,108979,DB00126,10049848,112,10059,44,5901,0.024299984,1.493227025,1.043084335,2.170696994,0.071952809,DB0012610049848_,2.631744807,0.400939567,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,108980,DB00181,10049848,144,9712,63,5808,0.042629464,1.366883663,1.007862889,1.871772534,0.110986079,DB0018110049848_,2.198350496,0.31253345,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,108981,DB00203,10049848,62,13816,44,8894,0.619472273,0.907102477,0.6059457,1.368152538,0.760228331,DB0020310049848_,0.274136455,-0.097499851,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,108983,DB00745,10049848,49,2528,18,1065,0.686764244,1.146774654,0.652625752,2.101967916,0.81105262,DB0074510049848_,0.209422344,0.136953353,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,modafinil,DB00745
,108984,DB00788,10049848,55,9301,28,5033,0.908249949,1.062923423,0.661749233,1.74267763,0.958996855,DB0078810049848_,0.041867483,0.061023058,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,108986,DB13961,10049848,94,9363,61,6353,0.805722544,1.045593238,0.748316828,1.470170663,0.894887901,DB1396110049848_,0.111056819,0.044584416,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,109045,DB00476,10013395,41,17216,43,6134,1.28436319927843e-06,0.339728479,0.215741778,0.534262786,1.78905599857094e-05,DB0047610013395_,10.93123736,-1.07960857,male,10013395,Disorientation,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,109047,DB00921,10062355,51,5794,40,4863,0.8327467,1.070142573,0.692198988,1.664636058,0.912909484,DB0092110062355_,0.091118545,0.067791885,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,109048,DB00043,10008531,43,6370,9,2291,0.156513643,1.718331651,0.824502545,4.01513084,0.292756529,DB0004310008531_,1.228413976,0.54135385,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,109049,DB01409,10008531,73,5958,31,3935,0.043535891,1.555202105,1.006470616,2.454995011,0.112698532,DB0140910008531_,2.183038882,0.441605509,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,109053,DB00635,10014950,19,33034,43,23751,1.44375113734844e-05,0.317697716,0.174789182,0.5571494,0.000150026,DB0063510014950_,8.804704002,-1.146654926,male,10014950,Eosinophilia,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,109057,DB00043,10033371,178,6235,60,2240,0.709761339,1.065803197,0.787815482,1.458985387,0.826898779,DB0004310033371_,0.190072987,0.063728691,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,109067,DB00043,10068319,59,6354,20,2280,0.89844691,1.058531972,0.626493589,1.860454253,0.956410053,DB0004310068319_,0.044568532,0.056883016,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omalizumab,DB00043
,109068,DB00471,10068319,139,14050,40,5425,0.111230706,1.341719195,0.936448677,1.961131614,0.227908532,DB0047110068319_,1.478810904,0.293951773,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,109069,DB00682,10013990,44,19415,30,16334,0.414406974,1.233910562,0.758050452,2.033821709,0.583651467,DB0068210013990_,0.538451278,0.210188445,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,warfarin,DB00682
,109072,DB00688,10012174,52,6438,37,5341,0.522015406,1.165916563,0.749041833,1.831176122,0.680732019,DB0068810012174_,0.384586561,0.153507527,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,mycophenolate mofetil,DB00688
,109073,DB00864,10012174,58,6811,64,8328,0.584614601,1.108088857,0.761938739,1.608645075,0.732355822,DB0086410012174_,0.311488787,0.102636781,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,tacrolimus,DB00864
,109078,DB00635,10020583,49,33004,31,23763,0.650434482,1.138031314,0.71107674,1.84691838,0.785013507,DB0063510020583_,0.242054356,0.129299852,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,109083,DB00635,10021027,37,33016,29,23765,0.803069257,0.918370792,0.549414021,1.548686657,0.893413274,DB0063510021027_,0.112706013,-0.085154057,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,109084,DB00635,10027417,55,32998,86,23708,6.88966577945087e-06,0.459486904,0.321322771,0.652291251,7.83621224633779e-05,DB0063510027417_,9.454169879,-0.777644839,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,109085,DB00688,10027417,18,6472,36,5342,0.002262071,0.41272916,0.220383577,0.747097538,0.010755884,DB0068810027417_,4.532302365,-0.884963688,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,mycophenolate mofetil,DB00688
,109086,DB00864,10027417,31,6838,73,8319,0.002025954,0.516659682,0.327548245,0.797715212,0.009827851,DB0086410027417_,4.622534967,-0.660370877,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,tacrolimus,DB00864
,109087,DB00776,10021036,48,1857,36,1303,0.822509483,0.93557885,0.590965355,1.492877905,0.905668339,DB0077610021036_,0.099082112,-0.066589851,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,oxcarbazepine,DB00776
,109088,DB00169,10044034,175,38516,50,18125,0.001561962,1.647029501,1.195988063,2.304075372,0.007947382,DB0016910044034_,4.834912675,0.498973363,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,109098,DB01067,10013709,184,4177,170,4653,0.092365092,1.205667442,0.96921343,1.500479846,0.199009503,DB0106710013709_,1.614402701,0.187033308,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,109104,DB00688,10009657,31,6459,33,5345,0.317227302,0.777395375,0.459798622,1.311302487,0.485068042,DB0068810009657_,0.723466105,-0.25180621,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,109107,DB08912,10016256,75,1255,86,1448,1,1.006205997,0.721258899,1.401232639,1,DB0891210016256_,0,0.006186819,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dabrafenib,DB08912
,109108,DB08912,10028813,94,1236,56,1478,4.84503674322402e-05,2.006759327,1.413239358,2.871506304,0.000430315,DB0891210028813_,7.750992537,0.696521146,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dabrafenib,DB08912
,109121,DB01156,10014380,81,13541,54,6274,0.041242219,0.695001655,0.485835856,1.00106365,0.108194193,DB0115610014380_,2.223827585,-0.363841052,NA,10014380,Electrocardiogram QRS complex prolonged,10022891,Investigations,Inv,bupropion,DB01156
,109126,DB01156,10018100,146,13476,53,6275,0.126235599,1.282656558,0.929270719,1.794072311,0.250470106,DB0115610018100_,1.384415702,0.248933363,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,109127,DB00514,10021097,20,2146,44,1492,1.51778382740075e-05,0.316119155,0.175742215,0.550348506,0.000156554,DB0051410021097_,8.762109525,-1.151636063,male,10021097,Hypotension,10047065,Vascular disorders,Vasc,dextromethorphan,DB00514
,109136,DB00514,10037660,37,2129,22,1514,0.594655394,1.195925897,0.684018252,2.137663304,0.740481451,DB0051410037660_,0.300454695,0.178920695,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,dextromethorphan,DB00514
,109152,DB00316,10058267,51,65423,36,36917,0.315729398,0.799414494,0.511525704,1.261145849,0.483352655,DB0031610058267_,0.727008757,-0.223875702,NA,10058267,Troponin increased,10022891,Investigations,Inv,acetaminophen,DB00316
,109156,DB00065,10028813,270,9194,99,4858,0.001848507,1.441023846,1.137319753,1.838057164,0.00911937,DB0006510028813_,4.69735456,0.365353865,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,infliximab,DB00065
,109166,DB00480,10013687,31,67397,22,67640,0.219474864,1.414161501,0.792749293,2.563689667,0.372850897,DB0048010013687_,0.98657668,0.346536777,NA,10013687,Drug eruption,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,109168,DB01590,10017577,30,4708,24,2843,0.325244476,0.754877087,0.425686081,1.35215599,0.493629317,DB0159010017577_,0.705970415,-0.281200342,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,109169,DB00480,10028411,215,67213,220,67442,0.847794122,0.980599725,0.808512494,1.189220644,0.923872577,DB0048010028411_,0.07918112,-0.01959093,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,109170,DB01590,10028411,40,4698,25,2842,0.898322275,0.967882878,0.571566198,1.668540819,0.956365087,DB0159010028411_,0.044615548,-0.032644193,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,everolimus,DB01590
,109171,DB01590,10040047,36,4702,27,2840,0.433979817,0.80536488,0.474347366,1.382471308,0.602512493,DB0159010040047_,0.506646879,-0.216459837,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,everolimus,DB01590
,109173,DB00559,10061599,45,9614,6,3300,0.023481106,2.574378495,1.093447292,7.391423508,0.069997262,DB0055910061599_,2.65929915,0.945608144,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,bosentan,DB00559
,109187,DB00047,10024774,19,9266,32,8486,0.035456722,0.54379207,0.290991733,0.98984904,0.096403406,DB0004710024774_,2.339213748,-0.609188329,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,109188,DB00264,10024774,71,29536,71,24821,0.312206486,0.840369093,0.595904569,1.185160046,0.479701682,DB0026410024774_,0.734590864,-0.173914087,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,109189,DB00695,10024774,77,27972,79,20449,0.034977641,0.712560513,0.513475036,0.988441671,0.095372127,DB0069510024774_,2.349968916,-0.33889044,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,109193,DB01137,10013573,185,7587,111,5482,0.136303905,1.204233887,0.9440623,1.541949429,0.264526591,DB0113710013573_,1.329813499,0.185843586,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,109194,DB01137,10016322,75,7697,32,5561,0.013561509,1.693265995,1.103714063,2.651647757,0.045380556,DB0113710016322_,3.092671555,0.526659205,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,109200,DB00635,10060820,62,32991,19,23775,0.000653304,2.351543816,1.387126285,4.165766767,0.003868896,DB0063510060820_,5.554786123,0.855072055,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,109203,DB01137,10028334,109,7663,66,5527,0.280757486,1.191141479,0.867654167,1.645925869,0.444639819,DB0113710028334_,0.810490721,0.174912073,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,109205,DB08910,10003246,47,16697,32,17456,0.070917039,1.535485977,0.958834643,2.488086504,0.162927574,DB0891010003246_,1.81444951,0.428846928,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,pomalidomide,DB08910
,109206,DB08910,10013781,59,16685,33,17455,0.004545436,1.870340759,1.200818146,2.958524659,0.01892403,DB0891010013781_,3.96732274,0.626120638,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,109209,DB08910,10033775,100,16644,71,17417,0.013926532,1.473837903,1.075630916,2.02859506,0.04637383,DB0891010033775_,3.071019985,0.387869817,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,109210,DB08910,10046306,104,16640,65,17423,0.001140089,1.675250833,1.216217748,2.322077527,0.00613957,DB0891010046306_,5.093000492,0.515962905,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,109217,DB05679,10042609,48,6883,25,4884,0.234179433,1.362347186,0.822212654,2.308956787,0.391042906,DB0567910042609_,0.938937991,0.309209084,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,ustekinumab,DB05679
,109222,DB05679,10035664,82,6849,61,4848,0.798040413,0.951552165,0.673328816,1.350925575,0.890838937,DB0567910035664_,0.115591635,-0.04966077,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ustekinumab,DB05679
,109232,DB00887,10008479,75,2266,42,1773,0.089325498,1.397095503,0.939887058,2.100846926,0.194171413,DB0088710008479_,1.63901394,0.334395441,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,109252,DB00285,10028596,34,10917,31,3687,0.000140478,0.3704436,0.220588429,0.624226123,0.001066107,DB0028510028596_,6.843741369,-0.993054073,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,venlafaxine,DB00285
,109253,DB00563,10028596,81,46565,59,15289,7.5073458381256e-06,0.450767415,0.318177784,0.641906758,8.43834019051235e-05,DB0056310028596_,9.380139836,-0.796803782,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,methotrexate,DB00563
,109289,DB00480,10061590,32,67396,23,67639,0.227942304,1.396311443,0.791843873,2.498998391,0.383306472,DB0048010061590_,0.958920422,0.333834076,NA,10061590,Blood disorder,10005329,Blood and lymphatic system disorders,Blood,lenalidomide,DB00480
,109292,DB06273,10013700,255,4840,25,1385,1.16032478651212e-08,2.918573333,1.922267184,4.614831713,2.57485327255981e-07,DB0627310013700_,15.1723031,1.071094912,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,tocilizumab,DB06273
,109299,DB08908,10020100,63,10610,14,3265,0.344816326,1.384732211,0.766197378,2.680066667,0.514276965,DB0890810020100_,0.664993317,0.325506772,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,dimethyl fumarate,DB08908
,109308,DB00563,10012601,118,46528,29,15319,0.180194725,1.33965485,0.885800318,2.087674454,0.324057085,DB0056310012601_,1.12683559,0.292412006,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,109309,DB13961,10012601,36,9421,33,6381,0.220166503,0.738917458,0.447287396,1.224247105,0.373663442,DB1396110012601_,0.984399774,-0.302569058,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,fish oil,DB13961
,109310,DB13961,10040047,64,9393,68,6346,0.009779973,0.635903724,0.44412999,0.90950658,0.034967912,DB1396110040047_,3.353324451,-0.452708104,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,fish oil,DB13961
,109335,DB00254,10047942,73,5862,25,3363,0.026362135,1.675103091,1.048427551,2.759771057,0.076551191,DB0025410047942_,2.569795593,0.51587471,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,doxycycline,DB00254
,109336,DB00281,10047942,113,11345,48,5623,0.400810146,1.166787942,0.824063852,1.674148903,0.570682285,DB0028110047942_,0.560922643,0.154254625,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,lidocaine,DB00281
,109337,DB00341,10047942,125,11280,64,5004,0.383180102,0.866457597,0.634811652,1.192443324,0.553263698,DB0034110047942_,0.591920541,-0.143342107,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,cetirizine,DB00341
,109338,DB00471,10047942,127,14062,56,5409,0.407352778,0.87235894,0.631122097,1.219005632,0.576900203,DB0047110047942_,0.550085986,-0.136554311,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,montelukast,DB00471
,109354,DB06403,10010774,324,21147,92,6569,0.485733897,1.093971731,0.863763935,1.396853723,0.649779403,DB0640310010774_,0.431122353,0.089814864,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,109359,DB14512,10022437,63,4781,27,2385,0.574073454,1.163945194,0.728451522,1.906082908,0.72390898,DB1451210022437_,0.323089613,0.151815264,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,mometasone furoate,DB14512
,109360,DB00451,10040849,42,47229,13,15406,1,1.053842005,0.554788442,2.140381223,1,DB0045110040849_,0,0.052442538,NA,10040849,Skin fissures,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,109368,DB00203,10046306,163,13715,60,8878,0.000139428,1.758510193,1.298731342,2.408627178,0.001059207,DB0020310046306_,6.850234501,0.564466969,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,109403,DB00363,10009033,37,4591,28,6860,0.007349049,1.974431729,1.174169036,3.354370615,0.027832254,DB0036310009033_,3.581559729,0.680280625,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clozapine,DB00363
,109407,DB00334,10042464,30,2819,37,2775,0.390885523,0.798188952,0.474784173,1.331964248,0.560751853,DB0033410042464_,0.5784768,-0.225409927,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,109408,DB00254,10001760,47,5888,10,3378,0.002280461,2.696183723,1.342328288,5.992671046,0.010827659,DB0025410001760_,4.525651398,0.991837337,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,doxycycline,DB00254
,109410,DB00958,10001760,45,4549,17,2568,0.184129665,1.494238084,0.83657463,2.790821341,0.329073482,DB0095810001760_,1.111474203,0.401616434,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,carboplatin,DB00958
,109413,DB00958,10013573,94,4500,38,2547,0.082760635,1.400042749,0.947677562,2.104868761,0.18299586,DB0095810013573_,1.698291748,0.336502771,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,carboplatin,DB00958
,109417,DB01409,10000087,65,5966,30,3936,0.114339798,1.429383923,0.912078179,2.2870358,0.232644779,DB0140910000087_,1.458242542,0.357243529,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,tiotropium,DB01409
,109423,DB00480,10017626,157,67271,171,67491,0.472612609,0.921153675,0.736754123,1.151049448,0.638629572,DB0048010017626_,0.448430693,-0.0821284,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,lenalidomide,DB00480
,109425,DB00381,10013887,51,29309,63,22824,0.017766888,0.630421972,0.426897384,0.927052265,0.056316266,DB0038110013887_,2.876771864,-0.461365886,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,109437,DB00563,10001052,61,46585,40,15308,0.001093089,0.501104177,0.330745295,0.766773227,0.005926537,DB0056310001052_,5.128315144,-0.690941262,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,109446,DB00541,10045170,45,3089,99,4198,0.008062009,0.617773502,0.422975621,0.890304311,0.029975232,DB0054110045170_,3.507383855,-0.48163339,NA,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,vincristine,DB00541
,109447,DB00563,10045170,18,46628,40,15308,1.70753506657435e-12,0.147740614,0.079726929,0.263793288,7.38199987251758e-11,DB0056310045170_,23.32939144,-1.912297153,male,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,109448,DB00635,10045170,27,33026,85,23709,3.10201104065665e-13,0.228041171,0.142081816,0.355377256,1.49197365422983e-11,DB0063510045170_,24.92833618,-1.478229093,male,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,109450,DB00987,10045170,21,2083,59,2869,0.004165854,0.490307321,0.282032685,0.821999807,0.017651241,DB0098710045170_,4.036949159,-0.7127229,NA,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,cytarabine,DB00987
,109458,DB00541,10074170,24,3110,57,4240,0.023355892,0.574082297,0.339919504,0.942405623,0.069699202,DB0054110074170_,2.663566417,-0.554982518,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,vincristine,DB00541
,109459,DB00635,10074170,94,32959,68,23726,1,0.995105911,0.720324497,1.380871308,1,DB0063510074170_,0,-0.004906104,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,109472,DB00177,10018884,53,4747,34,2816,0.738656648,0.924730821,0.588393399,1.471065759,0.849604638,DB0017710018884_,0.16298417,-0.078252588,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,valsartan,DB00177
,109475,DB00331,10062352,44,24902,13,20739,0.000479969,2.818640081,1.490649177,5.705955566,0.002986386,DB0033110062352_,5.81369124,1.036254528,female,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,metformin,DB00331
,109476,DB01076,10062352,39,25708,25,25558,0.103319658,1.550876195,0.914863635,2.67486631,0.216024914,DB0107610062352_,1.532361537,0.438820058,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,109479,DB00581,10003445,35,2078,43,2026,0.36066802,0.793630921,0.490882809,1.275304148,0.530595892,DB0058110003445_,0.63375458,-0.231136761,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,lactulose,DB00581
,109481,DB08932,10003445,233,19210,81,6516,0.844868949,0.975718566,0.753386799,1.274522079,0.921659279,DB0893210003445_,0.081579669,-0.024581088,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,109483,DB00211,10007559,30,1406,36,1595,0.900937575,0.945355292,0.559191736,1.587858358,0.956813906,DB0021110007559_,0.044146362,-0.056194452,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,midodrine,DB00211
,109486,DB00211,10008479,44,1392,9,1622,7.38057840516157e-08,5.693396404,2.730732697,13.3125207,1.37441376818754e-06,DB0021110008479_,13.49748327,1.739306978,female,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,midodrine,DB00211
,109488,DB00211,10010264,61,1375,36,1595,0.001313425,1.965103968,1.272010222,3.075021876,0.006889518,DB0021110010264_,4.977754202,0.675545154,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,midodrine,DB00211
,109489,DB01220,10010264,53,1241,22,1114,0.002127318,2.161814456,1.282803725,3.758914518,0.010235502,DB0122010010264_,4.581892992,0.770947895,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,rifaximin,DB01220
,109490,DB00193,10020919,70,19250,32,8670,0.91512261,0.985227564,0.639202178,1.548482104,0.962082946,DB0019310020919_,0.03865461,-0.014882635,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,tramadol,DB00193
,109491,DB00635,10020919,140,32913,95,23699,0.691180778,1.061135283,0.811464727,1.392626038,0.813806812,DB0063510020919_,0.206032273,0.059339357,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,109492,DB00736,10020919,39,10552,14,5539,0.248542362,1.462256454,0.775909301,2.918231717,0.407938804,DB0073610020919_,0.896638106,0.379980759,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,esomeprazole,DB00736
,109496,DB00581,10019641,43,2070,46,2023,0.748068365,0.913588119,0.585708338,1.422484562,0.856905279,DB0058110019641_,0.154427893,-0.090375445,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,lactulose,DB00581
,109497,DB00635,10019641,38,33015,13,23781,0.022153211,2.105477606,1.096786903,4.308507074,0.06698075,DB0063510019641_,2.70335002,0.744542333,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,prednisone,DB00635
,109499,DB08932,10019641,86,19357,32,6565,0.671436063,0.911469413,0.600324869,1.415426105,0.800648592,DB0893210019641_,0.22233314,-0.092697242,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,macitentan,DB08932
,109504,DB08932,10019663,43,19400,17,6580,0.555938662,0.85794221,0.4788229,1.605699684,0.709344324,DB0893210019663_,0.343414223,-0.153218536,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,macitentan,DB08932
,109510,DB08932,10059570,54,19389,21,6576,0.595638547,0.872151641,0.517653841,1.521443098,0.74122358,DB0893210059570_,0.299452972,-0.13679197,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,macitentan,DB08932
,109519,DB00193,10064911,70,19250,10,8692,0.000148155,3.160485276,1.619703961,6.880339884,0.001114554,DB0019310064911_,6.799301063,1.150725584,female,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,109521,DB00736,10064911,38,10553,12,5541,0.136888134,1.66265436,0.849672063,3.497885714,0.265346947,DB0073610064911_,1.326717077,0.508415338,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,109527,DB00654,10028813,131,3685,53,2545,0.001007284,1.706909347,1.226295127,2.404938585,0.005538428,DB0065410028813_,5.196044622,0.534684336,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,latanoprost,DB00654
,109528,DB00193,10051398,44,19276,62,8640,5.48665049529503e-09,0.318110305,0.210917618,0.476182131,1.30630985750752e-07,DB0019310051398_,15.85088939,-1.145357084,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,tramadol,DB00193
,109532,DB00196,10074170,42,5041,27,3258,1,1.005355507,0.604171832,1.699350471,1,DB0019610074170_,0,0.005341217,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,fluconazole,DB00196
,109535,DB00451,10074170,70,47201,14,15405,0.099562578,1.631786076,0.91049117,3.13835075,0.210125043,DB0045110074170_,1.560052481,0.489675167,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,109544,DB01141,10053762,37,361,62,543,0.665959732,0.897708239,0.567872418,1.403158711,0.796847687,DB0114110053762_,0.227091726,-0.107910164,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,micafungin,DB01141
,109545,DB00355,10008469,39,1754,23,1240,0.517876501,1.198669922,0.694295882,2.113719692,0.677367825,DB0035510008469_,0.389540837,0.181212544,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,aztreonam,DB00355
,109546,DB00684,10008469,52,2740,33,2315,0.227397677,1.331267565,0.841196289,2.133895508,0.382635422,DB0068410008469_,0.960672644,0.286131545,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,tobramycin,DB00684
,109580,DB09153,10067482,55,7744,32,5667,0.328254121,1.2577465,0.797966339,2.012774176,0.496856387,DB0915310067482_,0.699454255,0.229321627,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,109598,DB00186,10000381,40,16861,14,9994,0.09201049,1.693478921,0.901447669,3.371622529,0.198435372,DB0018610000381_,1.617291814,0.526784946,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,109622,DB00472,10015150,67,10692,23,4289,0.560618867,1.168523207,0.71702762,1.96946163,0.713227651,DB0047210015150_,0.337954623,0.155740736,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,fluoxetine,DB00472
,109623,DB00727,10015150,35,3808,22,4151,0.045894774,1.734074358,0.987135008,3.109175893,0.117280199,DB0072710015150_,2.143189346,0.55047376,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,nitroglycerin,DB00727
,109624,DB00758,10015150,55,8245,53,10021,0.245067135,1.261245163,0.847963207,1.877415559,0.403823443,DB0075810015150_,0.906777519,0.232099458,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,clopidogrel,DB00758
,109628,DB00722,10023230,47,25356,31,26001,0.069126984,1.554672967,0.966889211,2.532367375,0.159778647,DB0072210023230_,1.833965877,0.441265213,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,109631,DB01076,10023230,50,25697,29,25554,0.023768756,1.714515364,1.063746674,2.810950099,0.070714418,DB0107610023230_,2.649105802,0.539130454,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,109633,DB00472,10023232,40,10719,15,4297,0.882395603,1.068999982,0.577077365,2.085350682,0.950859822,DB0047210023232_,0.050388628,0.066723615,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,fluoxetine,DB00472
,109634,DB00727,10023232,38,3805,27,4146,0.104703851,1.533443917,0.910015141,2.617166909,0.218051793,DB0072710023232_,1.52302266,0.427516132,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,nitroglycerin,DB00727
,109635,DB00758,10023232,54,8246,51,10023,0.202370762,1.286972933,0.860296309,1.927658595,0.351760051,DB0075810023232_,1.04480601,0.252292898,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,clopidogrel,DB00758
,109636,DB01067,10023232,34,4327,33,4790,0.624572034,1.140530585,0.684102238,1.903477073,0.764357757,DB0106710023232_,0.268719331,0.13149358,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,glipizide,DB01067
,109637,DB00758,10033425,208,8092,162,9912,1.81144207234596e-05,1.572667415,1.271762779,1.947604203,0.000182919,DB0075810033425_,8.606468404,0.452773168,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,clopidogrel,DB00758
,109638,DB00332,10048959,49,2635,23,1633,0.32783881,1.320213918,0.785675447,2.279723856,0.496356381,DB0033210048959_,0.700461101,0.277793782,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ipratropium,DB00332
,109641,DB00727,10053762,103,3740,98,4075,0.353276943,1.145142021,0.856729302,1.531464284,0.523060015,DB0072710053762_,0.648059071,0.135528665,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,nitroglycerin,DB00727
,109674,DB00051,10019974,199,25532,93,11327,0.70249504,0.949294901,0.737689336,1.229048469,0.821564909,DB0005110019974_,0.196544332,-0.05203578,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,adalimumab,DB00051
,109684,DB00279,10033371,62,1175,10,206,1,1.086883054,0.541844262,2.417291085,1,DB0027910033371_,0,0.083314017,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,liothyronine,DB00279
,109687,DB01238,10049119,40,5210,30,3472,0.626266279,0.888561792,0.53861205,1.480396941,0.765842851,DB0123810049119_,0.266778286,-0.118151087,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,109699,DB06285,10000087,87,8763,11,1095,1,0.988298228,0.523862705,2.059221302,1,DB0628510000087_,0,-0.011770776,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,teriparatide,DB06285
,109701,DB06285,10047700,108,8742,6,1100,0.049700475,2.264793804,1.003877291,6.322945418,0.124458341,DB0628510047700_,2.083784231,0.817483719,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,teriparatide,DB06285
,109709,DB00959,10002424,31,8047,24,4978,0.407774899,0.79906945,0.453328947,1.424591524,0.577218117,DB0095910002424_,0.549535065,-0.224307416,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,methylprednisolone,DB00959
,109710,DB00028,10020751,169,13289,61,5554,0.344904409,1.157883148,0.857636738,1.581104336,0.514332441,DB0002810020751_,0.664885451,0.146593466,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,human immunoglobulin g,DB00028
,109713,DB01012,10020772,68,10564,41,8644,0.147214196,1.357075612,0.906810229,2.053414533,0.280035109,DB0101210020772_,1.272840296,0.305332099,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,cinacalcet,DB01012
,109714,DB01012,10053762,181,10451,142,8543,0.735287449,1.041945553,0.830157971,1.309794052,0.847082337,DB0101210053762_,0.165957379,0.04108969,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cinacalcet,DB01012
,109717,DB01390,10013968,71,1338,50,1467,0.020009172,1.556656538,1.060185856,2.300320731,0.061784562,DB0139010013968_,2.784101749,0.442540276,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium bicarbonate,DB01390
,109718,DB00136,10016173,46,2046,40,1642,0.742665686,0.922942871,0.587772904,1.454632648,0.852611542,DB0013610016173_,0.159451238,-0.080187941,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,calcitriol,DB00136
,109720,DB06724,10030124,99,7830,49,3870,1,0.998592593,0.700533908,1.439830271,1,DB0672410030124_,0,-0.001408398,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,109721,DB00706,10042772,11,1064,157,15768,0.872967521,1.038321451,0.506282761,1.917168952,0.944569365,DB0070610042772_,0.057026154,0.03760542,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,109722,DB06724,10042772,65,7864,25,3894,0.312676034,1.287458098,0.798970267,2.135158048,0.480175833,DB0672410042772_,0.733602922,0.252669807,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,109725,DB00169,10049414,80,38611,51,18124,0.091553796,0.736295614,0.51162412,1.068175855,0.197755898,DB0016910049414_,1.620721846,-0.306123592,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,109728,DB00996,10049414,94,38859,47,22378,0.483808224,1.151776061,0.802853268,1.672073136,0.648060907,DB0099610049414_,0.433770595,0.141305152,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,109729,DB01076,10049414,68,25679,58,25525,0.422519612,1.165378165,0.80846676,1.684616619,0.591524426,DB0107610049414_,0.525052302,0.15304564,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,109730,DB01136,10049414,35,9849,47,11068,0.440050379,0.836856902,0.523903297,1.325478056,0.608354756,DB0113610049414_,0.496997087,-0.178102189,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,109733,DB11089,10049414,26,10149,31,8376,0.183266978,0.692210668,0.394405818,1.205735202,0.327966539,DB1108910049414_,1.11484369,-0.367864936,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,109755,DB01190,10000059,78,4856,20,2265,0.015866766,1.818956407,1.098395929,3.147924996,0.051512688,DB0119010000059_,2.965927131,0.598262934,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,clindamycin,DB01190
,109762,DB00635,10040808,42,33011,40,23754,0.218535078,0.755569839,0.478071619,1.195775101,0.371730597,DB0063510040808_,0.989585889,-0.280283061,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,109766,DB00635,10048762,54,32999,14,23780,0.000300094,2.779470551,1.522154848,5.41905723,0.002018674,DB0063510048762_,6.205314284,1.02226046,female,10048762,Tooth infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,109771,DB00635,10062556,37,33016,13,23781,0.030385648,2.05001015,1.064736823,4.203959269,0.085517619,DB0063510062556_,2.459032848,0.717844744,NA,10062556,Grip strength decreased,10022891,Investigations,Inv,prednisone,DB00635
,109781,DB00811,10013710,22,2776,65,4091,0.004060076,0.498839504,0.292112379,0.822193113,0.017299255,DB0081110013710_,4.057091829,-0.695470871,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,109782,DB00836,10013710,63,5472,70,4005,0.017109152,0.658758974,0.459950619,0.941817999,0.054659869,DB0083610013710_,2.906625498,-0.417397556,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,109783,DB00924,10013710,87,10075,37,4214,0.921446222,0.98348414,0.660971879,1.489297814,0.965256414,DB0092410013710_,0.035361499,-0.016653767,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,109805,DB08895,10001949,66,28048,10,6636,0.241420014,1.561494438,0.797380381,3.40840979,0.399535159,DB0889510001949_,0.91745351,0.445643336,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,109807,DB00887,10003658,51,2290,54,1761,0.111264786,0.726338803,0.482892191,1.091158595,0.227958603,DB0088710003658_,1.478591231,-0.319738702,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,bumetanide,DB00887
,109808,DB00927,10003658,71,7426,84,4932,0.000372252,0.561411481,0.402566943,0.78102252,0.00241477,DB0092710003658_,6.026151134,-0.577301164,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,famotidine,DB00927
,109809,DB01413,10003658,17,1203,37,1622,0.125694424,0.619586288,0.325497115,1.134542406,0.249631881,DB0141310003658_,1.387767923,-0.478703302,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,cefepime,DB01413
,109810,DB09020,10003658,24,1930,36,1568,0.025349184,0.541725065,0.30775223,0.937852782,0.074268885,DB0902010003658_,2.600063195,-0.612996667,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,bisacodyl,DB09020
,109828,DB00327,10042772,31,6107,26,4236,0.501073015,0.827041078,0.474435458,1.45248884,0.662543599,DB0032710042772_,0.411668913,-0.189900914,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,109830,DB00887,10042772,36,2305,22,1793,0.424803668,1.272811452,0.725838273,2.27989219,0.593593276,DB0088710042772_,0.521560914,0.241228195,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,bumetanide,DB00887
,109833,DB00281,10001551,39,11419,19,5652,1,1.015988106,0.572494888,1.863178596,1,DB0028110001551_,0,0.015861642,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,lidocaine,DB00281
,109834,DB00319,10001551,21,1371,34,1819,0.495906378,0.819524712,0.449818899,1.460696559,0.658261749,DB0031910001551_,0.418152633,-0.199030727,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,piperacillin,DB00319
,109835,DB00451,10001551,151,47120,49,15370,1,1.005193316,0.723449835,1.418100719,1,DB0045110001551_,0,0.005179878,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,levothyroxine,DB00451
,109836,DB00813,10001551,45,10527,56,10112,0.231071863,0.771904865,0.509004126,1.164781988,0.387206676,DB0081310001551_,0.948796682,-0.258893968,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,fentanyl,DB00813
,109837,DB00927,10001551,62,7435,75,4941,0.000582942,0.549413066,0.38522793,0.781144464,0.003510336,DB0092710001551_,5.652043431,-0.598904723,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,famotidine,DB00927
,109839,DB00281,10003481,37,11421,22,5649,0.490957429,0.831875647,0.477477668,1.481898744,0.654175241,DB0028110003481_,0.424380011,-0.184072312,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,lidocaine,DB00281
,109840,DB00319,10003481,16,1376,34,1819,0.149230996,0.622180824,0.319296861,1.163945283,0.282939859,DB0031910003481_,1.262520916,-0.474524515,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,piperacillin,DB00319
,109841,DB00451,10003481,164,47107,54,15365,0.937308906,0.990597418,0.723823003,1.374288837,0.977296836,DB0045110003481_,0.022964849,-0.009447065,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,levothyroxine,DB00451
,109842,DB00927,10003481,64,7433,63,4953,0.02912997,0.676968364,0.469580265,0.976148092,0.082780828,DB0092710003481_,2.491558791,-0.390130736,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,famotidine,DB00927
,109849,DB00421,10022595,51,8852,51,5201,0.009750219,0.587601098,0.390015621,0.885212236,0.034880504,DB0042110022595_,3.35582723,-0.531706967,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,spironolactone,DB00421
,109854,DB00480,10029148,94,67334,164,67498,1.53886182493137e-05,0.574572611,0.440971175,0.745062473,0.000158436,DB0048010029148_,8.750159092,-0.5541288,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,109855,DB13961,10029148,54,9403,27,6387,0.212641125,1.358476462,0.839833149,2.245702132,0.364585107,DB1396110029148_,1.008995265,0.306363823,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,fish oil,DB13961
,109858,DB00169,10041660,20,38671,30,18145,5.12167065632621e-05,0.31281684,0.168357133,0.569541262,0.000451225,DB0016910041660_,7.703543453,-1.162137436,male,10041660,Splenomegaly,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,109867,DB01039,10005557,48,2925,43,3008,0.527924769,1.147927429,0.742169012,1.780471278,0.685443898,DB0103910005557_,0.377688624,0.13795808,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,fenofibrate,DB01039
,109868,DB00904,10046306,210,22859,126,14330,0.735585426,1.044813633,0.832924498,1.314968832,0.847238699,DB0090410046306_,0.165772807,0.043838527,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,ondansetron,DB00904
,109871,DB06228,10046306,60,15852,28,16048,0.00057017,2.169290625,1.362695005,3.53107508,0.003443686,DB0622810046306_,5.671212747,0.774400213,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,109883,DB01273,10027175,31,2009,19,1256,1,1.02003615,0.555584569,1.919940448,1,DB0127310027175_,0,0.019838068,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,varenicline,DB01273
,109889,DB01275,10033661,16,3963,35,3314,0.001062172,0.382326437,0.197235089,0.71072952,0.005789358,DB0127510033661_,5.151733907,-0.961480489,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,hydralazine,DB01275
,109891,DB00046,10053762,105,5354,105,4587,0.294177215,0.856757298,0.645442093,1.137256111,0.459990963,DB0004610053762_,0.776548435,-0.154600599,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin lispro,DB00046
,109892,DB01261,10053762,62,3719,57,3246,0.781905758,0.949360031,0.649675518,1.389584648,0.881222599,DB0126110053762_,0.126445019,-0.051967173,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sitagliptin,DB01261
,109893,DB01275,10053762,78,3901,79,3270,0.257174298,0.827659981,0.595285428,1.150537013,0.418034471,DB0127510053762_,0.872191383,-0.18915286,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,hydralazine,DB01275
,109894,DB09270,10053762,75,3039,49,2319,0.411198271,1.167937937,0.800597497,1.717283618,0.580547686,DB0927010053762_,0.543783335,0.155239747,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ubidecarenone,DB09270
,109896,DB00448,10000087,78,5067,28,3096,0.015352891,1.702003107,1.089559978,2.729859582,0.050217862,DB0044810000087_,2.991384493,0.531805856,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,lansoprazole,DB00448
,109901,DB00448,10044565,51,5094,22,3102,0.184644737,1.411604395,0.83893258,2.449347707,0.329731559,DB0044810044565_,1.109476414,0.344726927,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,lansoprazole,DB00448
,109913,DB05259,10061623,62,11208,16,2712,0.775518915,0.937628805,0.533447446,1.743721614,0.87775377,DB0525910061623_,0.130389169,-0.064401139,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,109915,DB00497,10009033,92,19175,66,16309,0.299508557,1.1855873,0.85423036,1.653226963,0.465502745,DB0049710009033_,0.764637285,0.170238263,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,109925,DB00653,10037423,59,1033,11,811,9.66705965266095e-07,4.208291944,2.171701526,8.944364215,1.38889676398028e-05,DB0065310037423_,11.18441573,1.437056851,female,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium sulfate,DB00653
,109926,DB01050,10037423,60,18048,17,9354,0.029561688,1.829203022,1.052563811,3.345951247,0.083749619,DB0105010037423_,2.479923654,0.603880365,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,109929,DB00555,10013722,24,7023,31,3455,0.00044816,0.38090533,0.213544196,0.671703178,0.002819167,DB0055510013722_,5.87131388,-0.965204413,NA,10013722,Drug level increased,10022891,Investigations,Inv,lamotrigine,DB00555
,109934,DB00682,10059168,54,19405,24,16340,0.008615026,1.89455566,1.150708578,3.205894444,0.031608914,DB0068210059168_,3.454316121,0.638984331,NA,10059168,Oxygen consumption increased,10022891,Investigations,Inv,warfarin,DB00682
,109940,DB08932,10040753,369,19074,56,6541,6.59888644095628e-10,2.259681796,1.699537359,3.053706452,1.89772133589208e-08,DB0893210040753_,17.78002687,0.815224005,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,macitentan,DB08932
,109941,DB08932,10044565,178,19265,62,6535,0.881464668,0.973878567,0.724508388,1.32409044,0.95045981,DB0893210044565_,0.050809401,-0.026468658,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,109958,DB00863,10003658,95,10578,87,5753,0.000571245,0.593868552,0.438482371,0.805222276,0.003448988,DB0086310003658_,5.669674468,-0.521097277,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ranitidine,DB00863
,109975,DB00047,10020919,49,9236,55,8463,0.325508757,0.816356495,0.543268289,1.223568763,0.493946605,DB0004710020919_,0.705327854,-0.202904138,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,insulin glargine,DB00047
,109976,DB00425,10020919,40,12655,16,7468,0.213443492,1.475278974,0.807268536,2.823977261,0.365555444,DB0042510020919_,1.006337317,0.388847107,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,zolpidem,DB00425
,109977,DB00451,10020919,188,47083,55,15364,0.502640326,1.115409097,0.821423176,1.536096631,0.663781198,DB0045110020919_,0.409802704,0.109221241,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,109978,DB00863,10020919,43,10630,21,5819,0.793507288,1.120900299,0.650029851,1.990411896,0.888018693,DB0086310020919_,0.118762485,0.114132201,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,ranitidine,DB00863
,109979,DB00887,10020919,88,2253,53,1762,0.142877395,1.298447101,0.907545129,1.872890961,0.273866573,DB0088710020919_,1.295114251,0.261169013,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,bumetanide,DB00887
,109980,DB01075,10020919,44,19904,27,11070,0.710649383,0.906355619,0.548567515,1.523062064,0.827428337,DB0107510020919_,0.189432778,-0.098323534,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,diphenhydramine,DB01075
,109981,DB01306,10020919,40,4168,26,3840,0.175298328,1.417327847,0.84207905,2.423973976,0.317828904,DB0130610020919_,1.146242079,0.348773301,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,insulin aspart,DB01306
,109982,DB11089,10020919,68,10107,47,8360,0.397807166,1.196714785,0.812106528,1.776558316,0.567463238,DB1108910020919_,0.56657931,0.179580124,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,109984,DB00203,10018092,44,13834,14,8924,0.02135548,2.027323082,1.089615914,4.007701901,0.065123127,DB0020310018092_,2.731475542,0.706716244,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,109986,DB00451,10018092,58,47213,13,15406,0.269660012,1.455800987,0.788123389,2.897125897,0.432235474,DB0045110018092_,0.83878476,0.375556256,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,110020,DB00887,10030095,94,2247,43,1772,0.003699177,1.72371257,1.182352019,2.547932944,0.016020803,DB0088710030095_,4.13386723,0.544480435,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,110021,DB00264,10039163,51,29556,20,24872,0.002804174,2.145803351,1.256598778,3.801058047,0.012789817,DB0026410039163_,4.359105962,0.763514005,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,metoprolol,DB00264
,110024,DB00887,10039163,45,2296,19,1796,0.030049193,1.852375325,1.057418201,3.365923815,0.084824468,DB0088710039163_,2.467171241,0.616468775,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,bumetanide,DB00887
,110028,DB08931,10040047,99,6478,50,2396,0.077707508,0.732364197,0.51434136,1.054204688,0.174475365,DB0893110040047_,1.745971722,-0.311477352,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,riociguat,DB08931
,110029,DB00047,10049414,34,9251,38,8480,0.410619397,0.820178468,0.500374352,1.339587499,0.580010793,DB0004710049414_,0.544708567,-0.198233318,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,110030,DB00203,10049414,96,13782,50,8888,0.234520941,1.238173256,0.869831677,1.781472421,0.391411228,DB0020310049414_,0.937996539,0.213637113,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,110031,DB00264,10049414,78,29529,67,24825,0.933546749,0.978719465,0.696698004,1.37812746,0.974166354,DB0026410049414_,0.026173195,-0.02151023,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,110034,DB00451,10049414,110,47161,37,15382,0.848357107,0.969661642,0.662289894,1.44877738,0.92428343,DB0045110049414_,0.078736512,-0.030808091,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,110035,DB00682,10049414,79,19380,62,16302,0.734959447,1.071841087,0.758343624,1.520732333,0.84679725,DB0068210049414_,0.166293987,0.069377812,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,110039,DB08931,10049414,49,6528,11,2435,0.145283283,1.661562981,0.850618632,3.549716599,0.277446316,DB0893110049414_,1.282127822,0.507758714,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,110057,DB01195,10013968,56,1183,18,726,0.019513278,1.908700427,1.095061173,3.478648551,0.060648899,DB0119510013968_,2.802653793,0.646422606,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,flecainide,DB01195
,110060,DB00193,10012601,53,19267,41,8661,0.010098669,0.581102394,0.37896137,0.896711733,0.03585863,DB0019310012601_,3.328171015,-0.5428283,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,tramadol,DB00193
,110067,DB00480,10029366,401,67027,389,67273,0.642846109,1.034640212,0.897293808,1.1930911,0.779247831,DB0048010029366_,0.249426144,0.034053745,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,110076,DB09140,10011224,312,3429,103,1695,0.000476161,1.497234612,1.184973367,1.903937156,0.002966204,DB0914010011224_,5.820472414,0.403619815,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,110080,DB09140,10040753,135,3606,20,1778,2.40230224710509e-08,3.327643239,2.063145668,5.640910965,4.95639831751626e-07,DB0914010040753_,14.51741632,1.202264317,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,oxygen,DB09140
,110082,DB00051,10060800,75,25656,12,11408,0.000407922,2.778997173,1.500100431,5.619520273,0.002605648,DB0005110060800_,5.950074034,1.022090134,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,adalimumab,DB00051
,110087,DB06228,10028596,67,15845,103,15973,0.007063855,0.655752267,0.474345133,0.901355177,0.026974191,DB0622810028596_,3.612874746,-0.421972203,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,110095,DB06228,10018870,104,15808,154,15922,0.00263269,0.680206287,0.524697233,0.878899455,0.012154255,DB0622810018870_,4.410075971,-0.385359164,NA,10018870,Blood urine present,10022891,Investigations,Inv,rivaroxaban,DB06228
,110102,DB00588,10038063,50,16474,19,8449,0.308780259,1.349657428,0.781147606,2.425698097,0.476098495,DB0058810038063_,0.742130523,0.299850803,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,110103,DB00904,10038063,62,23007,50,14406,0.206022634,0.776452511,0.526001632,1.151207804,0.356492869,DB0090410038063_,1.031441041,-0.253019796,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,110104,DB00927,10038063,31,7466,19,4997,0.885220992,1.092026851,0.596947784,2.048372528,0.952183569,DB0092710038063_,0.048997438,0.088035465,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,110128,DB08882,10011906,26,971,36,957,0.199444786,0.711933445,0.409310986,1.222899597,0.348378934,DB0888210011906_,1.054464501,-0.339770848,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,linagliptin,DB08882
,110133,DB00399,10061822,70,6922,42,4956,0.387502614,1.193266076,0.801057265,1.7967593,0.557541016,DB0039910061822_,0.584219207,0.176694149,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,110136,DB00455,10001551,42,9359,20,5098,0.690477778,1.143881692,0.65597032,2.05912408,0.813284927,DB0045510001551_,0.206673767,0.134427472,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,loratadine,DB00455
,110138,DB00455,10003481,35,9366,19,5099,1,1.002871342,0.557530655,1.857878608,1,DB0045510003481_,0,0.002867228,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,loratadine,DB00455
,110152,DB00343,10038695,98,8638,81,5014,0.023431972,0.70232611,0.516759075,0.956685756,0.069882498,DB0034310038695_,2.660940055,-0.353357438,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,110153,DB00343,10040560,31,8705,22,5073,0.478857131,0.821195444,0.459843738,1.490268899,0.64408759,DB0034310040560_,0.439920553,-0.196994141,NA,10040560,Shock,10047065,Vascular disorders,Vasc,diltiazem,DB00343
,110158,DB00343,10070863,322,8414,190,4905,0.888749236,0.987955999,0.820282905,1.19247006,0.953896257,DB0034310070863_,0.047200359,-0.012117117,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,110159,DB08932,10008531,269,19174,95,6502,0.716236486,0.960201671,0.755812157,1.228598372,0.832149303,DB0893210008531_,0.183743403,-0.040611942,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,110160,DB08932,10043521,130,19313,28,6569,0.027449041,1.579109595,1.042223822,2.470816427,0.078994695,DB0893210043521_,2.538374575,0.456861141,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,110179,DB08895,10008190,100,28014,45,6601,0.000623446,0.523662035,0.364405578,0.762783103,0.003719733,DB0889510008190_,5.594103486,-0.646908775,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,110181,DB08932,10042209,114,19329,9,6588,3.73389182531394e-07,4.317192024,2.194124557,9.690564251,5.94228896828162e-06,DB0893210042209_,12.03341615,1.462605196,female,10042209,Stress,10037175,Psychiatric disorders,Psych,macitentan,DB08932
,110183,DB08932,10049414,140,19303,52,6545,0.560814303,0.912865085,0.658668751,1.282135461,0.713366432,DB0893210049414_,0.337760061,-0.09116718,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,110218,DB08932,10061822,164,19279,43,6554,0.148368152,1.296547699,0.920557603,1.861135811,0.28175103,DB0893210061822_,1.266731471,0.259705116,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,110225,DB00537,10028334,93,7464,37,4261,0.06665925,1.434856737,0.968518108,2.165171582,0.155331416,DB0053710028334_,1.862194276,0.361065009,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ciprofloxacin,DB00537
,110228,DB00368,10013709,125,535,147,651,0.83949688,1.03470473,0.78674116,1.359450382,0.91779871,DB0036810013709_,0.085777182,0.034116101,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,norepinephrine,DB00368
,110229,DB00388,10013709,57,579,51,499,0.919449954,0.963237923,0.635633166,1.462849238,0.964382416,DB0038810013709_,0.036267366,-0.037454834,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,phenylephrine,DB00388
,110250,DB00413,10048959,73,2126,30,1177,0.209127625,1.347033739,0.863642232,2.148212131,0.360182133,DB0041310048959_,1.021145451,0.297904945,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,pramipexole,DB00413
,110256,DB00410,10010264,46,1559,19,990,0.123173395,1.537182788,0.877047682,2.79530891,0.245916425,DB0041010010264_,1.402763536,0.429951382,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,mupirocin,DB00410
,110257,DB00864,10010264,106,6763,144,8248,0.441901264,0.89777381,0.690380754,1.164322643,0.610013926,DB0086410010264_,0.494273492,-0.107837124,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,110274,DB00787,10040882,36,16964,33,17215,0.718464184,1.10704382,0.670576205,1.833144045,0.833712164,DB0078710040882_,0.181867064,0.101693237,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,110275,DB01076,10040882,56,25691,40,25543,0.125177612,1.391920421,0.910905816,2.144478724,0.248868735,DB0107610040882_,1.390829691,0.330684391,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,110278,DB00484,10013709,139,2368,70,1710,0.017385238,1.433822186,1.060570837,1.952766093,0.055370288,DB0048410013709_,2.893712146,0.360343736,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,brimonidine,DB00484
,110280,DB00924,10007515,132,10030,50,4201,0.568213019,1.105736946,0.791121383,1.566691978,0.719227546,DB0092410007515_,0.329577496,0.100512032,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,cyclobenzaprine,DB00924
,110281,DB06218,10007515,58,1636,18,1418,6.23624992337607e-05,2.791882316,1.612609596,5.059594277,0.000532467,DB0621810007515_,7.537990468,1.026716034,female,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,lacosamide,DB06218
,110285,DB06218,10033295,74,1620,69,1367,0.606460243,0.905003639,0.637682443,1.28569677,0.749362558,DB0621810033295_,0.288532356,-0.099816314,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lacosamide,DB06218
,110293,DB06605,10037844,344,13729,250,12783,0.003182613,1.28117215,1.083440597,1.516708258,0.014199265,DB0660510037844_,4.254565077,0.247775401,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,apixaban,DB06605
,110294,DB00706,10001760,13,1062,48,15877,9.17301346193537e-05,4.048668276,2.005687983,7.620385427,0.000741315,DB0070610001760_,7.207085108,1.398388006,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,tamsulosin,DB00706
,110318,DB06605,10048632,24,14049,35,12998,0.090602851,0.634431984,0.360835035,1.097986954,0.196169352,DB0660510048632_,1.628776952,-0.455025194,NA,10048632,Atrial thrombosis,10007541,Cardiac disorders,Card,apixaban,DB06605
,110321,DB00341,10011906,208,11197,150,4918,7.50257255714338e-06,0.609078254,0.489981732,0.758575531,8.43477842876449e-05,DB0034110011906_,9.380562017,-0.495808524,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,110322,DB00734,10012587,200,3850,196,4706,0.034160501,1.247246068,1.014243259,1.533961016,0.093736071,DB0073410012587_,2.367272205,0.220937975,NA,10012587,Device leakage,10077536,Product issues,Prod,risperidone,DB00734
,110323,DB00734,10064355,24,4026,74,4828,2.35380130585655e-05,0.388981323,0.234223151,0.625097072,0.000229551,DB0073410064355_,8.37938727,-0.94422395,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,110325,DB00695,10011469,42,28007,11,20517,0.001242726,2.796965927,1.414805786,6.025556971,0.006580391,DB0069510011469_,5.023661132,1.028535232,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,110326,DB00722,10011469,62,25341,14,26018,1.07798319788277e-08,4.54649506,2.51645378,8.79668949,2.40942077860108e-07,DB0072210011469_,15.23870927,1.51435662,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,110330,DB00695,10027091,58,27991,29,20499,0.103153772,1.464672316,0.922174731,2.37366301,0.215729555,DB0069510027091_,1.533729717,0.381631543,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,110332,DB00741,10030095,39,4055,16,3158,0.02926995,1.898130861,1.034312203,3.645403747,0.083090887,DB0074110030095_,2.48782025,0.640869645,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,110341,DB00537,10037087,175,7382,76,4222,0.046680164,1.316918586,0.9976237,1.752188208,0.118842375,DB0053710037087_,2.129957241,0.275294603,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ciprofloxacin,DB00537
,110344,DB00537,10046735,136,7421,45,4253,0.00133305,1.731970917,1.225184572,2.488875322,0.006975757,DB0053710046735_,4.965314417,0.549260019,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,ciprofloxacin,DB00537
,110347,DB09037,10011906,180,2346,213,2622,0.599959165,0.944482264,0.764017119,1.166634737,0.744506371,DB0903710011906_,0.29503387,-0.05711837,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pembrolizumab,DB09037
,110349,DB01306,10007559,56,4152,64,3802,0.232861836,0.801264855,0.548024113,1.168601737,0.389362173,DB0130610007559_,0.943245333,-0.221563731,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,insulin aspart,DB01306
,110351,DB01592,10008190,57,6219,34,3033,0.370112803,0.817648154,0.524307149,1.292649661,0.539747838,DB0159210008190_,0.616653216,-0.201323165,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,iron,DB01592
,110353,DB08895,10022437,373,27741,72,6574,0.114997456,1.227667678,0.950176973,1.60517999,0.23361219,DB0889510022437_,1.454092847,0.205116172,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,tofacitinib,DB08895
,110354,DB08895,10049187,85,28029,18,6628,0.801701209,1.116657191,0.665326222,1.975188975,0.892739804,DB0889510049187_,0.113460114,0.110339571,NA,10049187,Red blood cell sedimentation rate increased,10022891,Investigations,Inv,tofacitinib,DB08895
,110358,DB01098,10022437,133,8016,98,7111,0.183950879,1.203906989,0.918570762,1.58245112,0.328888131,DB0109810022437_,1.112037613,0.185572093,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,rosuvastatin,DB01098
,110379,DB00181,10047943,37,9819,24,5847,0.791177635,0.918035132,0.534143237,1.605811704,0.886940936,DB0018110047943_,0.119976887,-0.085519619,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,baclofen,DB00181
,110407,DB08934,10001760,89,4400,22,6182,1.61262503584525e-16,5.683416207,3.52549821,9.536908007,1.18072002972681e-14,DB0893410001760_,32.07006685,1.737552497,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,sofosbuvir,DB08934
,110409,DB00879,10047895,12,1765,44,3668,0.085519154,0.566830612,0.271817054,1.095168038,0.187572677,DB0087910047895_,1.673588899,-0.567694765,NA,10047895,Weight decreased,10022891,Investigations,Inv,emtricitabine,DB00879
,110430,DB04844,10053762,127,549,103,366,0.202419405,0.822155382,0.607993495,1.11333672,0.351798073,DB0484410053762_,1.044697924,-0.195825872,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tetrabenazine,DB04844
,110445,DB00252,10053762,85,2147,80,1828,0.577063234,0.904656942,0.654305815,1.251765724,0.726231208,DB0025210053762_,0.319886846,-0.100199477,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,phenytoin,DB00252
,110458,DB00273,10001488,24,8457,38,2155,2.94178329514049e-12,0.160975973,0.092157127,0.276101931,1.22640402716523e-10,DB0027310001488_,22.8217646,-1.826500162,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,110460,DB00273,10001497,41,8440,32,2161,6.52607511710995e-06,0.328105127,0.201086758,0.539646323,7.46465989787794e-05,DB0027310001497_,9.502745595,-1.114421213,male,10001497,Agitation,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,110461,DB00334,10001497,58,2791,127,2685,1.26920873270611e-07,0.439407406,0.314893343,0.607023288,2.25846276595875e-06,DB0033410001497_,13.00082617,-0.822328264,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,110465,DB01097,10037660,76,6189,21,1482,0.604432539,0.866595985,0.526751669,1.484756597,0.74779372,DB0109710037660_,0.290628115,-0.143182403,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,110473,DB00448,10022086,44,5101,10,3114,0.002872579,2.68577368,1.329285214,5.994450703,0.01305086,DB0044810022086_,4.338901249,0.987968835,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,110474,DB00678,10022086,124,15475,46,10678,0.000219012,1.859995984,1.314799142,2.67160087,0.001555453,DB0067810022086_,6.465988225,0.620574328,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,110485,DB00451,10061309,136,47135,37,15382,0.37656608,1.199509487,0.828251381,1.776116285,0.546415271,DB0045110061309_,0.604376023,0.181912713,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levothyroxine,DB00451
,110490,DB00624,10022086,11,551,43,4353,0.048504232,2.020635309,0.934014266,4.014082073,0.12226062,DB0062410022086_,2.101600281,0.703411971,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,testosterone,DB00624
,110491,DB00795,10022086,108,4461,17,1486,0.00314829,2.116104971,1.256954657,3.778719244,0.01407241,DB0079510022086_,4.263539135,0.749577121,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,110492,DB00158,10022107,60,16755,7,8097,3.70810060952007e-05,4.141528481,1.890369217,10.74335269,0.000341631,DB0015810022107_,7.981778322,1.421064918,female,10022107,Injection site urticaria,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,110500,DB00572,10013573,88,2814,49,2077,0.135846668,1.325485128,0.919678818,1.929370745,0.263882156,DB0057210013573_,1.332252654,0.281778527,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,atropine,DB00572
,110513,DB00722,10047654,20,25383,33,25999,0.099528124,0.620777574,0.337459175,1.114700095,0.210102227,DB0072210047654_,1.560161072,-0.476782435,NA,10047654,Vitreous floaters,10015919,Eye disorders,Eye,lisinopril,DB00722
,110535,DB00316,10035759,56,65418,56,36897,0.002972677,0.564051771,0.382301987,0.832114069,0.013405991,DB0031610035759_,4.31205362,-0.572609239,NA,10035759,Pneumothorax,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,110568,DB00230,10017885,96,19578,33,8618,0.250342033,1.280504075,0.853359294,1.965646357,0.410086024,DB0023010017885_,0.891388328,0.247253809,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,110570,DB00476,10017885,104,17153,23,6154,0.033920594,1.622319376,1.023992437,2.673649552,0.093229761,DB0047610017885_,2.372688282,0.483856839,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,110571,DB00788,10017885,80,9276,22,5039,0.003458708,1.975297271,1.217870493,3.33049394,0.01517732,DB0078810017885_,4.187953042,0.680718904,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,110572,DB00761,10020937,181,15126,60,8565,0.00025538,1.708131924,1.267357079,2.330346204,0.00176765,DB0076110020937_,6.338104081,0.535400331,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,110574,DB00316,10027566,64,65410,20,36933,0.022399797,1.806832064,1.079008375,3.153092504,0.067505005,DB0031610027566_,2.695553538,0.591575071,NA,10027566,Micturition urgency,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,110582,DB00476,10028391,124,17133,35,6142,0.240319083,1.270050898,0.865523336,1.907312078,0.398208857,DB0047610028391_,0.920778644,0.239056977,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,110583,DB00761,10028391,85,15222,27,8598,0.007665146,1.778161012,1.140371108,2.855140414,0.028782624,DB0076110028391_,3.547983414,0.575579691,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,110584,DB00813,10028391,37,10535,19,10149,0.031324451,1.875952744,1.05072902,3.455803904,0.087624456,DB0081310028391_,2.434695141,0.62911666,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fentanyl,DB00813
,110585,DB00761,10028836,74,15233,26,8599,0.03690402,1.606618403,1.014420772,2.619847052,0.099392608,DB0076110028836_,2.308677533,0.474131599,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,110586,DB00813,10028836,38,10534,15,10153,0.002383005,2.4414278,1.311145793,4.781051015,0.011224314,DB0081310028836_,4.489672998,0.892583032,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fentanyl,DB00813
,110587,DB00230,10031009,44,19630,6,8645,0.003179119,3.229252193,1.370421603,9.276039558,0.014187289,DB0023010031009_,4.255408872,1.172250591,female,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,110589,DB00695,10031009,79,27970,38,20490,0.038806069,1.522961184,1.021363127,2.306638206,0.103265447,DB0069510031009_,2.270452453,0.420656587,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,110593,DB00788,10033775,119,9237,52,5009,0.226533371,1.241004447,0.886953224,1.757111129,0.38157191,DB0078810033775_,0.963455952,0.21592109,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,110594,DB00230,10036018,52,19622,13,8638,0.078695315,1.760849439,0.944853752,3.527013347,0.176133034,DB0023010036018_,1.736515696,0.565796328,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,pregabalin,DB00230
,110596,DB00476,10036018,45,17212,13,6164,0.553459068,1.23963324,0.656637006,2.506439894,0.707011279,DB0047610036018_,0.346708661,0.214815562,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,duloxetine,DB00476
,110597,DB00695,10036018,97,27952,60,20468,0.331824932,1.183794402,0.848805898,1.662669059,0.50061807,DB0069510036018_,0.691911803,0.168724874,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,110598,DB00761,10036018,57,15250,21,8604,0.09895061,1.531365208,0.913380182,2.661555334,0.209270368,DB0076110036018_,1.564128235,0.426159631,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,potassium chloride,DB00761
,110606,DB00761,10052904,74,15233,27,8598,0.060979577,1.546936333,0.982650267,2.502892223,0.145275801,DB0076110052904_,1.929121264,0.436276416,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,110607,DB00476,10074903,245,17012,62,6115,0.013132971,1.420355581,1.069200126,1.91153335,0.044250755,DB0047610074903_,3.117882845,0.35090725,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,110608,DB00761,10074903,54,15253,15,8610,0.01202938,2.032069309,1.129391867,3.879876132,0.041227232,DB0076110074903_,3.188656278,0.709054638,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,110609,DB00813,10074903,118,10454,132,10036,0.251942687,0.858202795,0.662709405,1.110314414,0.412027596,DB0081310074903_,0.886664952,-0.152914849,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,110611,DB01275,10003658,52,3927,48,3301,0.686381393,0.910652189,0.601435477,1.381361619,0.810800841,DB0127510003658_,0.209732827,-0.093594245,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,hydralazine,DB01275
,110614,DB01062,10007559,37,4449,14,1731,1,1.028285814,0.541322088,2.064460241,1,DB0106210007559_,0,0.027893157,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,oxybutynin,DB01062
,110616,DB08910,10007559,92,16652,96,17392,1,1.000920791,0.743071282,1.347564023,1,DB0891010007559_,0,0.000920367,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,pomalidomide,DB08910
,110617,DB09270,10007559,22,3092,41,2327,0.000491373,0.403892047,0.228460492,0.696280597,0.003050398,DB0927010007559_,5.792483346,-0.906607648,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,ubidecarenone,DB09270
,110618,DB01015,10013573,220,9667,150,9231,0.001605081,1.400487809,1.130521682,1.738759045,0.008118032,DB0101510013573_,4.813667506,0.336820611,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,110619,DB01275,10013573,102,3877,86,3263,1,0.998212681,0.738879298,1.35118679,1,DB0127510013573_,0,-0.001788918,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,hydralazine,DB01275
,110620,DB09270,10013573,134,2980,98,2270,0.78677696,1.041568558,0.791894941,1.373824292,0.884327142,DB0927010013573_,0.122928215,0.040727806,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ubidecarenone,DB09270
,110621,DB09401,10013573,26,734,33,727,0.425832521,0.780494157,0.443395329,1.360811107,0.594582089,DB0940110013573_,0.519896492,-0.247828025,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,isosorbide,DB09401
,110622,DB00115,10019301,50,18375,33,10439,0.495180391,0.860781329,0.543312393,1.380195472,0.657505187,DB0011510019301_,0.419302626,-0.14991478,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,110624,DB00316,10019301,105,65369,56,36897,0.805468486,1.058332341,0.757895553,1.491566999,0.894731171,DB0031610019301_,0.111231973,0.056694406,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,110625,DB00338,10019301,62,33612,40,22232,0.919823047,1.025218221,0.677768298,1.566640608,0.964515682,DB0033810019301_,0.036129187,0.024905489,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,omeprazole,DB00338
,110628,DB00695,10019301,72,27977,57,20471,0.6566009,0.924265004,0.643591872,1.332823455,0.790020726,DB0069510019301_,0.235696099,-0.078756448,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,furosemide,DB00695
,110630,DB00996,10019301,69,38884,46,22379,0.439588186,0.863305967,0.585745054,1.282846191,0.607927575,DB0099610019301_,0.497699523,-0.146986112,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,gabapentin,DB00996
,110637,DB08910,10019301,45,16699,50,17438,0.83730067,0.939808725,0.613671189,1.435679906,0.91617884,DB0891010019301_,0.087543693,-0.062078908,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,pomalidomide,DB08910
,110644,DB01060,10037087,203,8384,86,4995,0.008127538,1.406278664,1.084752903,1.836105287,0.030174057,DB0106010037087_,3.500772758,0.34094697,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,amoxicillin,DB01060
,110645,DB00575,10022086,47,5197,33,3796,0.909795638,1.040297643,0.651149281,1.679598051,0.959437782,DB0057510022086_,0.04140781,0.039506868,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,110708,DB00537,10068319,45,7512,18,4280,0.237417738,1.424347221,0.807022324,2.617961267,0.394791555,DB0053710068319_,0.929397362,0.353713618,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ciprofloxacin,DB00537
,110711,DB14512,10068319,45,4799,15,2397,0.215186896,1.49835963,0.817753726,2.90007542,0.367631052,DB1451210068319_,1.000675419,0.40437093,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mometasone furoate,DB14512
,110719,DB00285,10006784,39,10912,14,3704,0.874483876,0.945589884,0.501604347,1.887647547,0.945626193,DB0028510006784_,0.055907933,-0.055946331,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,110726,DB00285,10013911,39,10912,13,3705,1,1.018607701,0.531539786,2.082135725,1,DB0028510013911_,0,0.018436696,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,110733,DB08875,10013968,26,617,39,1204,0.351176326,1.300690597,0.752676651,2.214829884,0.520874064,DB0887510013968_,0.652246986,0.262895352,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cabozantinib,DB08875
,110745,DB00956,10020642,51,5763,24,3443,0.401650731,1.269522473,0.765597526,2.160744444,0.571407416,DB0095610020642_,0.55965281,0.238640824,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocodone,DB00956
,110748,DB13961,10020642,71,9386,38,6376,0.281257443,1.269217285,0.843120949,1.937426374,0.445231828,DB1396110020642_,0.809160171,0.238400399,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,fish oil,DB13961
,110752,DB00497,10021114,36,19231,15,16360,0.023519663,2.041623612,1.089757918,4.015259129,0.070100276,DB0049710021114_,2.657828549,0.71374538,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,oxycodone,DB00497
,110768,DB00281,10024264,55,11403,38,5633,0.121847437,0.714980888,0.463763239,1.11269819,0.244038393,DB0028110024264_,1.410429717,-0.335499467,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,110769,DB00437,10024264,34,6887,49,11497,0.570082403,1.15832759,0.724393497,1.832949872,0.720856239,DB0043710024264_,0.327315553,0.146977232,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,110773,DB13961,10024264,34,9423,30,6384,0.308574061,0.767846436,0.455518822,1.300340403,0.475920153,DB1396110024264_,0.742505186,-0.264165518,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,110774,DB00177,10028334,70,4730,39,2811,0.84192576,1.066675653,0.708849532,1.625805493,0.919459817,DB0017710028334_,0.083968937,0.064546946,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,valsartan,DB00177
,110775,DB00285,10028334,128,10823,47,3671,0.66207452,0.923735538,0.654923477,1.32236239,0.793987989,DB0028510028334_,0.230686945,-0.079329463,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,venlafaxine,DB00285
,110781,DB00451,10031009,174,47097,45,15374,0.181405294,1.262193292,0.904340219,1.79417982,0.3256326,DB0045110031009_,1.121985527,0.232850916,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,110782,DB00497,10031009,55,19212,37,16338,0.295583208,1.264107382,0.817876922,1.973776453,0.461434529,DB0049710031009_,0.7734151,0.234366246,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,110786,DB13961,10031009,40,9417,20,6394,0.293196087,1.357943542,0.774491354,2.45421831,0.458815583,DB1396110031009_,0.77910693,0.305971454,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,110803,DB00177,10037377,38,4762,22,2828,1,1.025769958,0.590073507,1.824728041,1,DB0017710037377_,0,0.025443509,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,valsartan,DB00177
,110804,DB00425,10037377,79,12616,64,7420,0.067684686,0.726020745,0.514832452,1.02713221,0.157177487,DB0042510037377_,1.850379623,-0.32017669,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,110808,DB08875,10042128,30,613,49,1194,0.468241099,1.192399749,0.722841029,1.938606456,0.634778343,DB0887510042128_,0.454479407,0.175967873,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,cabozantinib,DB08875
,110809,DB13961,10042128,61,9396,31,6383,0.202113903,1.33672493,0.852883575,2.133922944,0.351499532,DB1396110042128_,1.045546898,0.29022254,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,110812,DB00285,10047340,54,10897,9,3709,0.042411536,2.042241245,0.998696081,4.709556423,0.110506268,DB0028510047340_,2.202683034,0.714047854,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,venlafaxine,DB00285
,110816,DB13961,10047340,52,9405,14,6400,0.001474076,2.527384199,1.378781534,4.942784937,0.007580922,DB1396110047340_,4.88212044,0.927184854,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,fish oil,DB13961
,110828,DB01075,10040829,46,19902,15,11082,0.08151072,1.707579488,0.935709868,3.294405978,0.180886425,DB0107510040829_,1.70988593,0.535076864,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,110857,DB00915,10013709,135,1320,91,960,0.62119802,1.07891093,0.80981814,1.442442818,0.761528748,DB0091510013709_,0.272427355,0.075952134,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,amantadine,DB00915
,110858,DB01217,10013709,72,2682,12,256,0.080426143,0.572838847,0.303511722,1.175680729,0.17912987,DB0121710013709_,1.719644208,-0.557150846,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,anastrozole,DB01217
,110873,DB09072,10024264,146,6325,62,2473,0.585641099,0.920726053,0.676888624,1.264904735,0.733044896,DB0907210024264_,0.31054833,-0.082592732,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,110874,DB00273,10033775,161,8320,31,2162,0.148760982,1.349530592,0.911379139,2.057740346,0.282291033,DB0027310033775_,1.264816709,0.299756822,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,110876,DB00669,10033775,85,6292,10,1087,0.306882523,1.468383432,0.757556479,3.182249608,0.473929847,DB0066910033775_,0.746695971,0.384162089,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,sumatriptan,DB00669
,110878,DB00669,10044565,53,6324,13,1084,0.291725507,0.698866911,0.374276222,1.402341838,0.457204482,DB0066910044565_,0.782624545,-0.358294955,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,sumatriptan,DB00669
,110881,DB00338,10050819,63,33611,44,22228,0.768049494,0.94691861,0.633894913,1.42556008,0.872719842,DB0033810050819_,0.136140688,-0.054542134,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,110884,DB01373,10050819,56,22664,17,7364,0.892117723,1.070322017,0.612428606,1.966184308,0.955096007,DB0137310050819_,0.045943412,0.067959554,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,110886,DB00126,10060795,43,10128,21,5924,0.603858879,1.197705853,0.694537996,2.126870662,0.747359951,DB0012610060795_,0.291208348,0.180407938,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,ascorbic acid,DB00126
,110890,DB00273,10061428,110,8371,31,2162,0.674770765,0.916445535,0.608447966,1.417141887,0.802790166,DB0027310061428_,0.219661912,-0.087252641,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,topiramate,DB00273
,110891,DB00669,10061428,50,6327,8,1089,1,1.075754141,0.504199747,2.635009037,1,DB0066910061428_,0,0.073021942,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,sumatriptan,DB00669
,110892,DB00471,10000087,180,14009,66,5399,0.774779381,1.051063357,0.787087956,1.418156293,0.877243929,DB0047110000087_,0.130970185,0.049802373,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,110894,DB00588,10000087,252,16272,72,8396,4.83828395733185e-06,1.805885186,1.382705459,2.383807145,5.74539389286052e-05,DB0058810000087_,9.764526993,0.59105088,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,110898,DB01234,10000087,315,31310,190,32698,1.72618813870733e-09,1.731362854,1.440521095,2.085503679,4.56697083300676e-08,DB0123410000087_,16.9018306,0.548908875,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,110904,DB00196,10013710,110,4973,130,3155,2.32097791800507e-06,0.536882143,0.410953687,0.700299126,3.01605622797276e-05,DB0019610013710_,10.40897537,-0.621976682,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,110949,DB01234,10047899,490,31135,388,32500,5.15846998880469e-05,1.318242472,1.150416166,1.511421225,0.00045348,DB0123410047899_,7.698560396,0.276299389,NA,10047899,Weight increased,10022891,Investigations,Inv,dexamethasone,DB01234
,110950,DB00196,10050584,37,5046,18,3267,0.336422221,1.33081169,0.737232287,2.487527998,0.505508379,DB0019610050584_,0.682190665,0.28578905,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,fluconazole,DB00196
,110951,DB00207,10050584,53,9027,12,5443,0.00118131,2.662944996,1.403376857,5.479889003,0.006321402,DB0020710050584_,5.063814246,0.979432652,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,azithromycin,DB00207
,110952,DB00471,10050584,138,14051,28,5437,0.001221285,1.907054527,1.261536452,2.978154233,0.006488425,DB0047110050584_,5.037735411,0.645559919,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,110957,DB01015,10050584,74,9813,24,9357,1.22002480888268e-06,2.940165488,1.831548173,4.876830514,1.70985615043888e-05,DB0101510050584_,10.97651622,1.078465868,female,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,sulfamethoxazole,DB01015
,110959,DB00196,10061428,79,5004,55,3230,0.721444045,0.927158349,0.646929424,1.336907186,0.835799546,DB0019610061428_,0.179366472,-0.075630909,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,fluconazole,DB00196
,110960,DB00207,10061428,108,8972,61,5394,0.749463874,1.06442857,0.769078084,1.484710215,0.858009244,DB0020710061428_,0.153140405,0.062438101,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,azithromycin,DB00207
,110977,DB00153,10008479,124,7299,44,3395,0.132751058,1.310846525,0.919935722,1.898133382,0.259652386,DB0015310008479_,1.34841152,0.270673131,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,110994,DB00136,10037660,31,2061,33,1649,0.257200504,0.751669983,0.443194997,1.271967904,0.418064143,DB0013610037660_,0.872120406,-0.285457903,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,calcitriol,DB00136
,111009,DB01307,10047899,39,2485,21,2048,0.119246484,1.530413904,0.875237383,2.747624686,0.240201842,DB0130710047899_,1.426275701,0.425538224,NA,10047899,Weight increased,10022891,Investigations,Inv,insulin detemir,DB01307
,111010,DB06655,10053762,143,3545,56,2063,0.01327624,1.485945501,1.078119078,2.07211963,0.044610543,DB0665510053762_,3.109785068,0.396051271,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,liraglutide,DB06655
,111019,DB00471,10067482,74,14115,33,5432,0.516183501,0.862994371,0.564538046,1.344805045,0.675910196,DB0047110067482_,0.391695058,-0.147347111,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,111022,DB01257,10054112,37,899,23,545,1,0.97524096,0.557512878,1.738877039,1,DB0125710054112_,0,-0.0250707,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,eculizumab,DB01257
,111031,DB00722,10005839,23,25380,31,26001,0.342592195,0.760095353,0.423106841,1.346972175,0.511926088,DB0072210005839_,0.669575024,-0.274311389,NA,10005839,Blood triglycerides increased,10022891,Investigations,Inv,lisinopril,DB00722
,111035,DB00863,10005557,66,10607,37,5803,0.917851102,0.975878923,0.642009046,1.503622001,0.96354479,DB0086310005557_,0.037136305,-0.024416754,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,ranitidine,DB00863
,111041,DB06616,10035598,23,938,34,769,0.031039085,0.554784561,0.309182898,0.978998648,0.086999403,DB0661610035598_,2.441854027,-0.589175419,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosutinib,DB06616
,111057,DB08932,10018830,56,19387,23,6574,0.438070719,0.825601408,0.499410734,1.407120574,0.606476097,DB0893210018830_,0.500089962,-0.191643179,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,111061,DB00005,10062189,59,128023,23,42396,0.523072381,0.849524444,0.5166543,1.441565376,0.681467995,DB0000510062189_,0.383505991,-0.163078564,NA,10062189,Vitamin D decreased,10022891,Investigations,Inv,etanercept,DB00005
,111071,DB00264,10047899,432,29175,269,24623,9.68649800017735e-05,1.35537166,1.160129367,1.585646469,0.000774949,DB0026410047899_,7.162712921,0.304075705,NA,10047899,Weight increased,10022891,Investigations,Inv,metoprolol,DB00264
,111085,DB00316,10008589,49,65425,14,36939,0.024951785,1.976088477,1.073404306,3.876451376,0.073366259,DB0031610008589_,2.612291134,0.681119374,NA,10008589,Choking,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,111099,DB01222,10007882,58,9216,51,5354,0.035942414,0.66073093,0.4449679,0.983701828,0.09741852,DB0122210007882_,2.328738943,-0.414408588,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,budesonide,DB01222
,111138,DB00588,10030095,136,16388,52,8416,0.075213489,1.343124243,0.967816274,1.888411916,0.170209777,DB0058810030095_,1.770723622,0.294998425,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,111142,DB01222,10030095,91,9183,40,5365,0.145710087,1.329102368,0.905337919,1.982200429,0.278068117,DB0122210030095_,1.279889171,0.284503803,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,111180,DB06655,10024574,44,3644,30,2089,0.468048012,0.840831067,0.515025315,1.389758393,0.634614774,DB0665510024574_,0.45473712,-0.173364511,NA,10024574,Lipase increased,10022891,Investigations,Inv,liraglutide,DB06655
,111182,DB01137,10037377,55,7717,54,5539,0.118464539,0.731085808,0.492141011,1.086396174,0.238892208,DB0113710037377_,1.43174284,-0.313224441,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,111200,DB00196,10000081,100,4983,54,3231,0.317658437,1.200695448,0.851219708,1.709603769,0.485543687,DB0019610000081_,0.722486012,0.182900929,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,fluconazole,DB00196
,111223,DB00203,10059168,123,13755,43,8895,0.000413375,1.849738088,1.29585477,2.685302487,0.002632834,DB0020310059168_,5.939694462,0.615044055,NA,10059168,Oxygen consumption increased,10022891,Investigations,Inv,sildenafil,DB00203
,111224,DB00559,10059168,50,9609,21,3285,0.415136162,0.813964426,0.479218399,1.429062136,0.584365341,DB0055910059168_,0.537228908,-0.205838617,NA,10059168,Oxygen consumption increased,10022891,Investigations,Inv,bosentan,DB00559
,111225,DB00374,10062244,82,17634,15,5709,0.043405708,1.769719023,1.011944958,3.30788775,0.112446294,DB0037410062244_,2.185279562,0.57082079,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,111231,DB00065,10013968,287,9177,133,4824,0.251457701,1.13433111,0.91745328,1.408193756,0.411439239,DB0006510013968_,0.888093926,0.126043147,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,infliximab,DB00065
,111233,DB00065,10016256,186,9278,66,4891,0.005974887,1.485597279,1.113581455,2.002700922,0.023584607,DB0006510016256_,3.747161031,0.395816899,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,111237,DB00065,10020937,62,9402,22,4935,0.133824793,1.479193059,0.895305582,2.530507614,0.261083997,DB0006510020937_,1.342913095,0.391496709,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,infliximab,DB00065
,111261,DB00863,10009033,47,10626,35,5805,0.166404464,0.733644553,0.463012813,1.172308961,0.305991048,DB0086310009033_,1.184199433,-0.309730628,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,111264,DB00904,10058467,31,23038,21,14435,0.777318981,0.924944604,0.514514563,1.6942139,0.878599416,DB0090410058467_,0.129426212,-0.078021431,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ondansetron,DB00904
,111334,DB00635,10022972,43,33010,21,23773,0.163398163,1.474634232,0.855855195,2.616702911,0.301927643,DB0063510022972_,1.197567884,0.388409981,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,111336,DB00635,10035618,33,33020,18,23776,0.395280916,1.320081653,0.721833979,2.490594335,0.564978732,DB0063510035618_,0.570967192,0.277693593,NA,10035618,Pleurisy,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,111358,DB00996,10013952,142,38811,49,22376,0.001532823,1.670768426,1.199088083,2.362588053,0.007831713,DB0099610013952_,4.849573984,0.513283656,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,111359,DB00996,10022052,126,38827,24,22401,3.47934054394036e-08,3.0289002,1.945501768,4.903638139,6.93362139480457e-07,DB0099610022052_,14.18171341,1.108199583,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,111360,DB00996,10022067,47,38906,23,22402,0.619606327,1.176659172,0.70005939,2.030816395,0.760331312,DB0099610022067_,0.274001004,0.162679213,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,111367,DB00996,10039674,89,38864,34,22391,0.048536251,1.508114171,1.004957143,2.310778629,0.122314314,DB0099610039674_,2.101161205,0.410859977,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,111368,DB00996,10046735,342,38611,127,22298,1.40865273723413e-05,1.555156653,1.264081415,1.923130831,0.000146843,DB0099610046735_,8.826147251,0.441576282,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,111383,DB00158,10008190,129,16686,75,8029,0.202204169,0.827654743,0.617052877,1.116787656,0.351635879,DB0015810008190_,1.045159075,-0.189159188,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,111384,DB00455,10008190,55,9346,47,5071,0.028397996,0.634935147,0.421647683,0.95957004,0.081161391,DB0045510008190_,2.511315622,-0.454232416,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,111386,DB00455,10017955,55,9346,39,5079,0.233225347,0.766426365,0.498545829,1.188283733,0.38980881,DB0045510017955_,0.942098892,-0.266016651,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,111389,DB01413,10021097,63,1157,80,1579,0.728565074,1.074702378,0.753113052,1.528150786,0.841772878,DB0141310021097_,0.172245042,0.072043766,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,cefepime,DB01413
,111391,DB00215,10046571,238,10865,50,5226,1.56790511916012e-08,2.289433033,1.678355833,3.177135347,3.36565014758054e-07,DB0021510046571_,14.9044745,0.828304203,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,citalopram,DB00215
,111392,DB01216,10046571,7,229,148,6967,0.350117489,1.438849441,0.56216544,3.088183386,0.519742681,DB0121610046571_,0.654421434,0.363843795,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,finasteride,DB01216
,111393,DB14726,10046571,38,1979,24,2824,0.00172023,2.259025135,1.3156643,3.950339192,0.008588082,DB1472610046571_,4.757379813,0.814933364,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,dabigatran,DB14726
,111404,DB00471,10021789,178,14011,56,5409,0.211883898,1.227074856,0.90244644,1.69086394,0.363654473,DB0047110021789_,1.011551113,0.204633171,NA,10021789,Infection,10021881,Infections and infestations,Infec,montelukast,DB00471
,111405,DB00471,10022998,42,14147,18,5447,0.667957397,0.898412415,0.505556021,1.659561601,0.798311289,DB0047110022998_,0.225256671,-0.107126057,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,montelukast,DB00471
,111406,DB00588,10022998,46,16478,27,8441,0.62059409,0.872748299,0.530825483,1.461091398,0.761119619,DB0058810022998_,0.272964747,-0.136108082,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,111412,DB00471,10042772,78,14111,29,5436,0.91429078,1.036165283,0.667800596,1.64829994,0.961631513,DB0047110042772_,0.039123944,0.03552667,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,111420,DB00471,10051055,66,14123,36,5429,0.096664441,0.704762332,0.462065765,1.090583913,0.205765155,DB0047110051055_,1.581019785,-0.349894651,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,montelukast,DB00471
,111429,DB00588,10061224,41,16483,14,8454,0.202045795,1.502018181,0.80155473,2.985021683,0.351404335,DB0058810061224_,1.045817766,0.406809658,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,111431,DB00588,10061225,39,16485,17,8451,0.672147463,1.176050301,0.649455545,2.218519119,0.800970013,DB0058810061225_,0.22193177,0.162161622,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,111435,DB00471,10061623,66,14123,38,5427,0.048735307,0.667425771,0.440625846,1.023995587,0.122682287,DB0047110061623_,2.0981573,-0.4043271,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,111436,DB00588,10061623,84,16440,45,8423,0.852106437,0.95639088,0.657500498,1.407371021,0.927437586,DB0058810061623_,0.075329779,-0.044588579,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,111449,DB00524,10012174,48,1529,51,1293,0.304975395,0.795972815,0.521442068,1.213358968,0.471767788,DB0052410012174_,0.751268389,-0.228190245,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,metolazone,DB00524
,111452,DB00641,10029148,46,14078,32,12443,0.30890218,1.270537583,0.791266909,2.062957618,0.476230611,DB0064110029148_,0.741853064,0.239440104,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,simvastatin,DB00641
,111464,DB00688,10013971,34,6456,31,5347,0.709572917,0.908380251,0.540976169,1.530520865,0.826752549,DB0068810013971_,0.190249844,-0.09609221,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolate mofetil,DB00688
,111496,DB00207,10010774,109,8971,62,5393,0.751343734,1.05687824,0.765307573,1.470610732,0.859589556,DB0020710010774_,0.151300264,0.055319506,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,111573,DB00254,10000087,59,5876,24,3364,0.170149836,1.407342513,0.860222048,2.370351629,0.311046942,DB0025410000087_,1.16781144,0.341703183,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,doxycycline,DB00254
,111585,DB01098,10010264,128,8021,75,7134,0.004527849,1.517890026,1.130510538,2.050196454,0.018865736,DB0109810010264_,3.970407891,0.41732123,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,111611,DB00682,10001760,153,19306,30,16334,5.90680348030713e-17,4.314665393,2.900855965,6.615689008,4.50029940521371e-15,DB0068210001760_,33.03463247,1.462019776,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,111612,DB01268,10001760,61,2082,25,3105,1.23707636362708e-08,3.638000482,2.24146582,6.070618088,2.7301891031014e-07,DB0126810001760_,15.11372478,1.291434213,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,sunitinib,DB01268
,111613,DB00273,10013946,44,8437,10,2183,0.866004952,1.138447524,0.563358812,2.541112765,0.939258929,DB0027310013946_,0.062664088,0.129665513,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,topiramate,DB00273
,111614,DB00682,10013946,184,19275,78,16286,1.40741891238238e-07,1.993091641,1.520056463,2.634337105,2.47700074402215e-06,DB0068210013946_,12.90846211,0.689687022,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,111615,DB01225,10013946,37,5007,13,4627,0.001702193,2.62973723,1.364227099,5.398475283,0.008515017,DB0122510013946_,4.765924002,0.966883929,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,111616,DB13961,10013946,97,9360,39,6375,0.004893405,1.693936074,1.155170725,2.52722715,0.020117799,DB1396110013946_,3.906150357,0.527054859,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,111627,DB01225,10053762,109,4935,104,4536,0.835260938,0.963330389,0.727230852,1.276685039,0.914708514,DB0122510053762_,0.089149828,-0.037358843,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,enoxaparin,DB01225
,111632,DB00331,10064911,41,24905,22,20730,0.100705238,1.551203718,0.902344716,2.735257766,0.211955109,DB0033110064911_,1.551380775,0.439031222,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,111641,DB00555,10011224,73,6974,27,3459,0.202025359,1.340989542,0.849894723,2.173823174,0.351402697,DB0055510011224_,1.045822428,0.293407805,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lamotrigine,DB00555
,111643,DB00316,10061355,85,65389,35,36918,0.128026922,1.371143887,0.914634305,2.095272954,0.252879027,DB0031610061355_,1.374844059,0.315645345,NA,10061355,Poisoning,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,111669,DB00433,10007559,48,7608,45,5975,0.40348025,0.837728447,0.545228532,1.289141412,0.573207134,DB0043310007559_,0.556508138,-0.17706128,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,prochlorperazine,DB00433
,111670,DB00215,10035598,36,11067,18,5258,0.884344324,0.950215929,0.52508913,1.779187366,0.951843037,DB0021510035598_,0.049355134,-0.051066026,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,111671,DB00887,10035598,60,2281,31,1784,0.069109184,1.513618772,0.960754856,2.427564916,0.159751553,DB0088710035598_,1.834135463,0.414503322,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bumetanide,DB00887
,111672,DB00332,10000081,34,2650,21,1635,1,0.998922055,0.561118391,1.817885926,1,DB0033210000081_,0,-0.001078526,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ipratropium,DB00332
,111673,DB00437,10000081,104,6817,152,11394,0.298751886,1.143582674,0.880801278,1.480003574,0.464738908,DB0043710000081_,0.766279519,0.134166031,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,111675,DB00887,10000081,53,2288,16,1799,0.000520667,2.603944682,1.459953949,4.897464278,0.003192752,DB0088710000081_,5.746872101,0.957027481,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,bumetanide,DB00887
,111676,DB00973,10000081,56,3795,33,2988,0.198505253,1.336055426,0.851426392,2.126791763,0.34726859,DB0097310000081_,1.057656764,0.289721561,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ezetimibe,DB00973
,111678,DB00887,10002855,45,2296,17,1798,0.009613356,2.072550148,1.158573201,3.876563904,0.034494172,DB0088710002855_,3.366964885,0.728779804,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,bumetanide,DB00887
,111696,DB01136,10003553,43,9841,10,11105,5.22289373996308e-07,4.851524758,2.399227534,10.83448525,8.054195479902e-06,DB0113610003553_,11.72931742,1.579293039,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,111712,DB00437,10006002,33,6888,33,11513,0.041159055,1.671336587,0.99890424,2.796738953,0.108019146,DB0043710006002_,2.225446786,0.513623658,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,allopurinol,DB00437
,111713,DB00588,10006002,71,16453,18,8450,0.006722756,2.025753164,1.193572916,3.614261199,0.025938737,DB0058810006002_,3.652017784,0.705941564,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,111715,DB00678,10006002,75,15524,27,10697,0.003255351,1.914010131,1.217157788,3.094087324,0.014453866,DB0067810006002_,4.236793329,0.649200586,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,111716,DB00695,10006002,116,27933,42,20486,4.92231769545286e-05,2.025532215,1.411129749,2.957325016,0.000435854,DB0069510006002_,7.73820431,0.705832488,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,111720,DB00620,10007559,31,4797,22,3110,0.778639599,0.913556041,0.511111101,1.659236855,0.879344398,DB0062010007559_,0.128578651,-0.090410557,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,triamcinolone,DB00620
,111724,DB00887,10016256,162,2179,112,1703,0.345099358,1.130406674,0.875303473,1.463879054,0.514527096,DB0088710016256_,0.66450706,0.122577456,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,111725,DB00437,10020635,30,6891,43,11503,0.545628836,1.164596386,0.704691767,1.90191989,0.700377128,DB0043710020635_,0.356136335,0.152374577,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,allopurinol,DB00437
,111726,DB00451,10020635,79,47192,36,15383,0.103666758,0.715319229,0.476310518,1.092935214,0.216514371,DB0045110020635_,1.530098356,-0.335026362,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,111728,DB00678,10020635,30,15569,21,10703,1,0.982074812,0.543540597,1.805750721,1,DB0067810020635_,0,-0.01808779,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,111734,DB00437,10033318,42,6879,53,11493,0.201960325,1.323930511,0.860580874,2.025292663,0.351361474,DB0043710033318_,1.045939745,0.280604972,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,allopurinol,DB00437
,111737,DB00887,10033318,52,2289,28,1787,0.138557614,1.449725368,0.89468065,2.394446701,0.26776362,DB0088710033318_,1.317650704,0.371374137,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,bumetanide,DB00887
,111744,DB00451,10050528,32,47239,18,15401,0.070243768,0.579602716,0.315553016,1.097054238,0.161712936,DB0045110050528_,1.821932518,-0.545412382,NA,10050528,Ejection fraction decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,111748,DB00695,10050528,43,28006,43,20485,0.156087146,0.731464833,0.467807178,1.143672927,0.292260339,DB0069510050528_,1.230110303,-0.312706135,NA,10050528,Ejection fraction decreased,10022891,Investigations,Inv,furosemide,DB00695
,111758,DB00186,10062237,42,16859,44,9964,0.009756208,0.564193102,0.360389483,0.882011771,0.03489864,DB0018610062237_,3.355307423,-0.572358707,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,lorazepam,DB00186
,111761,DB00887,10062237,30,2311,28,1787,0.506530728,0.828532336,0.476410025,1.444992134,0.667292829,DB0088710062237_,0.404526305,-0.188099413,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,bumetanide,DB00887
,111770,DB00999,10069868,49,21381,7,12232,0.00012269,4.004547508,1.80355883,10.48513989,0.000950456,DB0099910069868_,6.958568587,1.387430592,female,10069868,Device issue,10077536,Product issues,Prod,hydrochlorothiazide,DB00999
,111779,DB00175,10008190,78,8053,93,6013,0.002405891,0.626279472,0.456594833,0.857079465,0.011312854,DB0017510008190_,4.481815715,-0.467958566,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,111782,DB00175,10044390,35,8096,22,6084,0.592266453,1.195522648,0.681151325,2.141749315,0.738465935,DB0017510044390_,0.303180305,0.178583452,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,111785,DB00422,10046571,65,3370,23,2926,0.000137319,2.453330784,1.499785231,4.148147877,0.001045452,DB0042210046571_,6.863305685,0.897446605,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,methylphenidate,DB00422
,111792,DB00448,10027599,40,5105,11,3113,0.019554126,2.217241241,1.11445661,4.79929224,0.060725448,DB0044810027599_,2.801392422,0.796263739,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,lansoprazole,DB00448
,111794,DB00455,10051055,55,9346,44,5074,0.057806341,0.678623128,0.447506627,1.034460312,0.139353388,DB0045510051055_,1.970742216,-0.387689345,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,loratadine,DB00455
,111806,DB00341,10037377,74,11331,39,5029,0.413271791,0.84215741,0.56308498,1.276918744,0.58269272,DB0034110037377_,0.540095298,-0.171788335,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,111827,DB00395,10013709,127,2057,36,700,0.403315028,1.200426669,0.814240833,1.808154902,0.573080818,DB0039510013709_,0.556728528,0.182677051,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,carisoprodol,DB00395
,111830,DB00395,10025482,87,2097,22,714,0.260643305,1.346313333,0.828126044,2.275728369,0.422107099,DB0039510025482_,0.862496209,0.297369992,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,carisoprodol,DB00395
,111839,DB00335,10069327,45,8421,25,5440,0.623990653,1.16283546,0.697001703,1.981171495,0.763942865,DB0033510069327_,0.269262277,0.150861384,NA,10069327,Product quality issue,10077536,Product issues,Prod,atenolol,DB00335
,111844,DB00422,10027599,42,3393,16,2933,0.005051239,2.268777048,1.246014704,4.332457598,0.020627953,DB0042210027599_,3.881108205,0.819240941,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,methylphenidate,DB00422
,111874,DB01225,10015090,52,4992,55,4585,0.496510464,0.868384848,0.581452602,1.295331902,0.658664457,DB0122510015090_,0.417541045,-0.141120289,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enoxaparin,DB01225
,111882,DB00404,10051055,99,19793,74,9788,0.009317395,0.661578735,0.484098812,0.907543009,0.03363193,DB0040410051055_,3.392279354,-0.413126278,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,alprazolam,DB00404
,111913,DB00433,10052904,40,7616,12,6008,0.001968812,2.629329491,1.350895955,5.510999292,0.009610963,DB0043310052904_,4.644850807,0.966728867,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,prochlorperazine,DB00433
,111916,DB00904,10052904,84,22985,26,14430,0.001130289,2.028239678,1.292262263,3.283210139,0.006094679,DB0090410052904_,5.100339168,0.707168263,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,111928,DB00997,10063743,40,5291,24,3490,0.798052618,1.099358629,0.645445617,1.910070584,0.890838937,DB0099710063743_,0.115591635,0.094726946,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,doxorubicin,DB00997
,111933,DB00381,10013395,48,29312,44,22843,0.462440766,0.850156411,0.552642397,1.310673692,0.629675483,DB0038110013395_,0.462550699,-0.162334933,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,111942,DB00334,10040047,50,2799,48,2764,0.919074371,1.028642005,0.675675312,1.567417191,0.964259603,DB0033410040047_,0.036394723,0.02823949,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,olanzapine,DB00334
,111945,DB01268,10000081,57,2086,84,3046,1,0.990858893,0.69179796,1.410580272,1,DB0126810000081_,0,-0.009183143,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,111946,DB00338,10005555,76,33598,38,22234,0.179895988,1.323524139,0.884993156,2.009292086,0.32371038,DB0033810005555_,1.127906052,0.280297981,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,omeprazole,DB00338
,111947,DB00338,10015916,52,33622,25,22247,0.201556919,1.37628577,0.838466555,2.315311707,0.350948835,DB0033810015916_,1.047114836,0.3193884,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,omeprazole,DB00338
,111948,DB00722,10015916,56,25347,31,26001,0.00521205,1.853027122,1.173870967,2.974439787,0.021149941,DB0072210015916_,3.856118178,0.616820584,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,lisinopril,DB00722
,111964,DB00121,10020937,74,4149,7,461,0.851774602,1.174596446,0.538151049,3.040767542,0.927210793,DB0012110020937_,0.075574346,0.160924638,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,biotin,DB00121
,111966,DB00338,10027599,255,33419,57,22215,3.59089549587675e-16,2.973765042,2.222608862,4.038167768,2.52033880131162e-14,DB0033810027599_,31.31179796,1.089828841,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,111976,DB00795,10023232,107,4462,17,1486,0.003099212,2.096044063,1.24453205,3.743661247,0.0138932,DB0079510023232_,4.276355751,0.740051789,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfasalazine,DB00795
,112025,DB06403,10003445,104,21367,45,6616,0.06618273,0.71561353,0.499236334,1.040320248,0.154492821,DB0640310003445_,1.86760765,-0.33461502,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,112026,DB06403,10006002,77,21394,21,6640,0.720916135,1.138007315,0.694340052,1.943343207,0.835410838,DB0640310006002_,0.179831654,0.129278764,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,112027,DB00820,10008469,262,11653,61,5755,2.12845909192693e-08,2.121108833,1.596673469,2.856087314,4.43844087515266e-07,DB0082010008469_,14.62779249,0.751938987,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,112028,DB00820,10016322,385,11530,147,5669,0.009877657,1.287740047,1.059170152,1.572263114,0.035215914,DB0082010016322_,3.346257198,0.252888781,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,112029,DB01240,10016322,186,5565,57,1519,0.474712669,0.890696074,0.654823104,1.227287255,0.640380935,DB0124010016322_,0.445692069,-0.115752016,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,112030,DB00820,10029331,51,11864,33,5783,0.202283281,0.753300692,0.476273836,1.206473662,0.35168096,DB0082010029331_,1.045030879,-0.283290805,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,112033,DB00820,10051099,83,11832,16,5800,0.000233906,2.542778392,1.475584291,4.65749557,0.001641494,DB0082010051099_,6.412148719,0.933257338,NA,10051099,Catheter site haemorrhage,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,112034,DB01240,10051099,190,5561,41,1535,0.167098425,1.279113435,0.903865244,1.848241737,0.306963142,DB0124010051099_,1.181027598,0.246167209,NA,10051099,Catheter site haemorrhage,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,112035,DB06403,10051099,55,21416,6,6655,0.009617857,2.848547213,1.227608285,8.100381248,0.034505611,DB0640310051099_,3.366633332,1.046809115,female,10051099,Catheter site haemorrhage,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,112036,DB01240,10068319,98,5653,16,1560,0.050857925,1.690111253,0.986873939,3.082164252,0.126626935,DB0124010068319_,2.066510038,0.524794357,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,112038,DB08881,10028813,56,567,45,766,0.012503166,1.680549558,1.097073385,2.586654851,0.042543134,DB0888110028813_,3.157236811,0.519120858,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,vemurafenib,DB08881
,112039,DB08881,10037844,109,514,151,660,0.628485375,0.926914394,0.698743893,1.226973233,0.767769948,DB0888110037844_,0.264265138,-0.075894065,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,vemurafenib,DB08881
,112040,DB00695,10040829,122,27927,62,20466,0.02025671,1.442026305,1.053147552,1.991744248,0.062425213,DB0069510040829_,2.77378603,0.366049281,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,112047,DB00836,10002855,81,5454,46,4029,0.175164943,1.300760638,0.892699771,1.915325995,0.317685126,DB0083610002855_,1.146694556,0.2629492,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,loperamide,DB00836
,112048,DB00836,10012378,65,5470,30,4045,0.03650488,1.602147118,1.02228434,2.563568497,0.098598945,DB0083610012378_,2.31669472,0.471344678,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,loperamide,DB00836
,112056,DB00588,10046543,52,16472,13,8455,0.017825376,2.053128689,1.101669826,4.11296276,0.056440403,DB0058810046543_,2.874570016,0.71936482,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,fluticasone propionate,DB00588
,112069,DB00641,10017533,35,14089,22,12453,0.232860266,1.406153204,0.801610815,2.517500031,0.389362173,DB0064110017533_,0.943245333,0.340857752,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,simvastatin,DB00641
,112076,DB00331,10000084,35,24911,17,20735,0.070623849,1.713665093,0.934331572,3.262952791,0.16239593,DB0033110000084_,1.817717916,0.538634406,NA,10000084,Abdominal pain lower,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,112093,DB00687,10003549,49,937,61,1024,0.556488391,0.877918206,0.583749118,1.314601271,0.709865827,DB0068710003549_,0.342679303,-0.130201849,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,fludrocortisone,DB00687
,112101,DB00512,10006093,23,4714,38,5060,0.12249868,0.649719062,0.36894317,1.120816873,0.245028769,DB0051210006093_,1.40637965,-0.431215221,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,vancomycin,DB00512
,112108,DB00687,10012735,61,925,40,1045,0.010359557,1.72236725,1.125239522,2.661518923,0.036614355,DB0068710012735_,3.30731491,0.543699653,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fludrocortisone,DB00687
,112112,DB00264,10013036,43,29564,21,24871,0.044140997,1.722557977,0.999743926,3.05675749,0.113866835,DB0026410013036_,2.172725628,0.543810382,NA,10013036,Diplopia,10015919,Eye disorders,Eye,metoprolol,DB00264
,112113,DB00331,10013036,33,24913,18,20734,0.160844444,1.525785856,0.834253419,2.878996437,0.298646909,DB0033110013036_,1.208493311,0.422509593,NA,10013036,Diplopia,10015919,Eye disorders,Eye,metformin,DB00331
,112120,DB00687,10013573,101,885,114,971,0.885369134,0.972066461,0.724600318,1.302656549,0.952284462,DB0068710013573_,0.048891484,-0.028331102,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,fludrocortisone,DB00687
,112145,DB00047,10020937,62,9223,58,8460,0.927189338,0.980529745,0.673386326,1.429558343,0.969321736,DB0004710020937_,0.031158693,-0.019662297,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,112149,DB01306,10020937,42,4166,31,3835,0.410303111,1.247157409,0.763834199,2.056595868,0.579719798,DB0130610020937_,0.545210399,0.220866889,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,insulin aspart,DB01306
,112155,DB00512,10021015,45,4692,32,5066,0.085330615,1.51826666,0.941958837,2.473160492,0.187299809,DB0051210021015_,1.675044691,0.417569329,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,vancomycin,DB00512
,112185,DB00331,10038063,62,24884,44,20708,0.436200481,1.172614549,0.783725175,1.767731452,0.604755735,DB0033110038063_,0.502930646,0.159235913,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,112201,DB00331,10040070,66,24880,54,20698,1,1.016783719,0.698490346,1.48568999,1,DB0033110040070_,0,0.016644429,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,metformin,DB00331
,112202,DB00381,10040070,47,29313,52,22835,0.085128211,0.704114949,0.464121311,1.065689178,0.186980449,DB0038110040070_,1.676751218,-0.350813656,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,amlodipine,DB00381
,112207,DB00727,10042772,32,3811,49,4124,0.14606619,0.706729987,0.437013545,1.128599707,0.278515214,DB0072710042772_,1.278282594,-0.347106599,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,112218,DB00727,10047513,31,3812,19,4154,0.047795275,1.777816764,0.971242266,3.336818886,0.120960793,DB0072710047513_,2.112288814,0.575386075,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,nitroglycerin,DB00727
,112221,DB00047,10058080,35,9250,31,8487,0.902461729,1.035907735,0.619828971,1.738889923,0.957195726,DB0004710058080_,0.043747388,0.035278081,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,112225,DB01306,10058080,31,4177,19,3847,0.200908496,1.502597741,0.820869989,2.820166436,0.350051692,DB0130610058080_,1.049674444,0.407195437,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,insulin aspart,DB01306
,112234,DB00820,10027599,190,11725,39,5777,8.17636732771507e-08,2.400271588,1.690608225,3.486045487,1.50765215860393e-06,DB0082010027599_,13.40495698,0.875581893,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,112235,DB06403,10027599,199,21272,50,6611,0.202847644,1.236906048,0.901901583,1.724426555,0.352379243,DB0640310027599_,1.043047288,0.212613139,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,112247,DB06168,10013709,43,566,21,379,0.291290471,1.370692913,0.781286782,2.472779746,0.45674054,DB0616810013709_,0.783639797,0.315316388,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,canakinumab,DB06168
,112256,DB01409,10013971,71,5960,44,3922,0.774697379,1.061861333,0.717257082,1.587328043,0.877201654,DB0140910013971_,0.131018376,0.060023343,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,112259,DB00177,10022437,88,4712,35,2815,0.047946641,1.501985757,1.001409722,2.297068784,0.121248717,DB0017710022437_,2.10991133,0.40678807,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,valsartan,DB00177
,112265,DB05679,10003549,39,6892,25,4884,0.799401439,1.10550735,0.651373559,1.908581317,0.891653766,DB0567910003549_,0.114677376,0.10030437,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,112266,DB05679,10010264,186,6745,99,4810,0.020657716,1.339769502,1.041191378,1.732455902,0.063392453,DB0567910010264_,2.758410455,0.292497586,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,112270,DB00814,10039073,186,8101,29,3386,5.53569344781247e-08,2.680599364,1.801468289,4.122521464,1.06107530100992e-06,DB0081410039073_,13.75622773,0.986040413,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,112277,DB00814,10043414,41,8246,16,3399,1,1.056256902,0.57910704,2.019316526,1,DB0081410043414_,0,0.054731434,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,112281,DB00169,10005839,32,38659,19,18156,0.452957217,0.791009597,0.434774746,1.477402185,0.620556485,DB0016910005839_,0.477138648,-0.234445178,NA,10005839,Blood triglycerides increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,112287,DB00996,10028810,492,38461,182,22243,1.55544859903586e-07,1.563375674,1.315122285,1.865079626,2.7130037442374e-06,DB0099610028810_,12.81745414,0.446847377,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,gabapentin,DB00996
,112289,DB01050,10042458,143,17965,52,9319,0.027920493,1.426492429,1.030621535,2.001120238,0.080053466,DB0105010042458_,2.52506054,0.355218584,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,112291,DB00996,10046306,231,38722,86,22339,0.000434881,1.549588579,1.203972316,2.010011215,0.002748462,DB0099610046306_,5.896713785,0.437989463,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,112300,DB00404,10006093,41,19851,30,9832,0.129000956,0.676887706,0.412189475,1.123413931,0.25415359,DB0040410006093_,1.36981651,-0.390249889,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,alprazolam,DB00404
,112301,DB00572,10006093,28,2874,31,2095,0.113272739,0.658474352,0.379277556,1.138414114,0.231001159,DB0057210006093_,1.465332553,-0.417829708,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,atropine,DB00572
,112303,DB00758,10006093,30,8270,45,10029,0.416266657,0.808474224,0.491274895,1.31315904,0.585533357,DB0075810006093_,0.535232126,-0.212606482,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,112314,DB01075,10007617,224,19724,116,10981,0.569452031,1.075075005,0.854252343,1.358818184,0.720292901,DB0107510007617_,0.328097343,0.072390431,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,112321,DB00682,10012442,87,19372,14,16350,1.39686192780742e-11,5.244621778,2.963021598,9.993176376,5.19695906191339e-10,DB0068210012442_,21.37777727,1.657203128,female,10012442,Dermatitis contact,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,112324,DB01225,10013573,94,4950,97,4543,0.46458884,0.889404319,0.660537014,1.19714766,0.631602455,DB0122510013573_,0.45949511,-0.117203345,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,enoxaparin,DB01225
,112325,DB00820,10015967,53,11862,16,5800,0.095485944,1.619627546,0.910805137,3.038173538,0.20399298,DB0082010015967_,1.589669699,0.482196213,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,tadalafil,DB00820
,112337,DB01088,10030095,58,1371,25,412,0.145443047,0.697331118,0.423131568,1.179024823,0.277650556,DB0108810030095_,1.28139195,-0.36049492,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,iloprost,DB01088
,112338,DB01225,10030095,37,5007,24,4616,0.199392537,1.421221596,0.826447195,2.487342774,0.348322389,DB0122510030095_,1.054626822,0.35151678,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,112341,DB01240,10037844,328,5423,81,1495,0.420859997,1.116307008,0.866518805,1.451755307,0.589863763,DB0124010037844_,0.527863679,0.110025923,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,epoprostenol,DB01240
,112347,DB00682,10046735,125,19334,56,16308,6.57608455497908e-05,1.882727439,1.362228259,2.630639085,0.000556511,DB0068210046735_,7.49382324,0.632721491,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,112349,DB01240,10046735,60,5691,13,1563,0.566423597,1.26754522,0.685933898,2.523704246,0.717809428,DB0124010046735_,0.331551165,0.237082133,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,epoprostenol,DB01240
,112358,DB00682,10061026,49,19410,32,16332,0.314944989,1.288416774,0.808312824,2.079820364,0.482518523,DB0068210061026_,0.72873597,0.253414157,NA,10061026,Cardiac operation,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,112366,DB06403,10061520,44,21427,11,6650,0.634345999,1.241409655,0.630415182,2.666927951,0.772654169,DB0640310061520_,0.257923719,0.216247553,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,112392,DB01409,10001760,63,5968,6,3960,1.47153254994975e-08,6.967575284,3.024042383,19.71458906,3.17955060217255e-07,DB0140910001760_,14.96135578,1.941267285,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,tiotropium,DB01409
,112393,DB00115,10029216,83,18342,19,10453,0.000120375,2.489466859,1.497563473,4.343653392,0.000934039,DB0011510029216_,6.975992122,0.912068575,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,112394,DB00126,10029216,44,10127,9,5936,0.002414557,2.86548447,1.379333981,6.680997855,0.01134447,DB0012610029216_,4.479024895,1.052737436,female,10029216,Nervousness,10037175,Psychiatric disorders,Psych,ascorbic acid,DB00126
,112395,DB00115,10036653,46,18379,21,10451,0.446911419,1.245617259,0.727971739,2.198791613,0.614723914,DB0011510036653_,0.486582032,0.219631197,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,112411,DB08880,10003549,94,3244,43,766,0.000891137,0.51625847,0.352890731,0.765662088,0.005010921,DB0888010003549_,5.296135646,-0.661147728,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,teriflunomide,DB08880
,112420,DB13961,10048334,40,9417,14,6400,0.036284064,1.941695281,1.033181848,3.867278604,0.098098154,DB1396110048334_,2.321786731,0.663561448,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,112423,DB06637,10051290,67,6095,20,1999,0.802965691,1.098698955,0.656536459,1.916829111,0.893342905,DB0663710051290_,0.11278478,0.094126712,NA,10051290,Central nervous system lesion,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,112425,DB00005,10015943,70,128012,18,42401,0.38870843,1.288091185,0.758703638,2.298530997,0.558598223,DB0000510015943_,0.582324807,0.253161421,NA,10015943,Eye inflammation,10015919,Eye disorders,Eye,etanercept,DB00005
,112428,DB01118,10033661,22,3041,31,4678,0.778840899,1.091690049,0.601042982,1.951355155,0.879487607,DB0111810033661_,0.128415806,0.087726999,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,amiodarone,DB01118
,112459,DB01233,10040047,42,3379,40,1686,0.004410323,0.523963572,0.33023257,0.832532229,0.018481588,DB0123310040047_,3.990980298,-0.646333116,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,metoclopramide,DB01233
,112460,DB09140,10040047,84,3657,57,1741,0.044955501,0.701611243,0.492729812,1.005206078,0.11548061,DB0914010040047_,2.158652644,-0.354375813,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,oxygen,DB09140
,112467,DB00213,10009033,162,18733,88,13333,0.045625391,1.310234624,1.003556667,1.720125726,0.116773456,DB0021310009033_,2.147519498,0.270206224,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,112469,DB00874,10009033,73,3262,43,1933,1,1.006008945,0.67781664,1.509035314,1,DB0087410009033_,0,0.005990963,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,guaifenesin,DB00874
,112471,DB00874,10013709,96,3239,53,1923,0.731178195,1.07537911,0.757211388,1.541279227,0.843642459,DB0087410013709_,0.170026501,0.07267326,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,112476,DB00758,10018867,22,8278,92,9982,1.16477681231802e-08,0.288380276,0.172227425,0.463584764,2.58037577006145e-07,DB0075810018867_,15.17016062,-1.243475266,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,clopidogrel,DB00758
,112483,DB00490,10028813,270,3800,72,1504,0.003405379,1.484125737,1.132002079,1.966168762,0.014991227,DB0049010028813_,4.200290088,0.394825869,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,buspirone,DB00490
,112484,DB00490,10035664,98,3972,23,1553,0.03089746,1.665828615,1.044730654,2.760469909,0.086702226,DB0049010035664_,2.445275725,0.510322666,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,buspirone,DB00490
,112485,DB00814,10035664,214,8073,94,3321,0.611499195,0.936532969,0.728864885,1.21085094,0.753518596,DB0081410035664_,0.283001581,-0.065570553,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,meloxicam,DB00814
,112486,DB00490,10046571,90,3980,7,1569,4.89892045739036e-07,5.067824116,2.353968505,12.99279159,7.61490977069815e-06,DB0049010046571_,11.78540242,1.622911557,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,buspirone,DB00490
,112487,DB00874,10046571,115,3220,37,1939,0.000841778,1.87141756,1.275784453,2.801549851,0.004774736,DB0087410046571_,5.344416599,0.626696197,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,guaifenesin,DB00874
,112488,DB14512,10046571,78,4766,18,2394,0.002102512,2.176467598,1.287574408,3.872003273,0.010135633,DB1451210046571_,4.591698057,0.777703195,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,mometasone furoate,DB14512
,112489,DB00656,10048393,122,11891,21,6598,3.17759682273747e-08,3.223382763,2.015375153,5.400042491,6.3953393940011e-07,DB0065610048393_,14.26252615,1.170431356,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,112490,DB00814,10048393,57,8230,11,3404,0.016014283,2.143128989,1.110611128,4.538163396,0.051861692,DB0081410048393_,2.959174874,0.762266906,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,112494,DB00996,10057668,149,38804,104,22321,0.132760062,0.824131632,0.636889706,1.069710035,0.259652386,DB0099610057668_,1.34841152,-0.193425015,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,112519,DB00338,10009900,43,33631,32,22240,0.637728395,0.888618611,0.549155834,1.451484938,0.774956235,DB0033810009900_,0.254948722,-0.118087145,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,112529,DB00203,10038669,18,13860,33,8905,0.000263228,0.350468355,0.185661076,0.641233027,0.001812666,DB0020310038669_,6.312956814,-1.048484862,male,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,112531,DB00695,10038669,44,28005,31,20497,0.90734559,1.038836712,0.641063803,1.702345172,0.958745315,DB0069510038669_,0.042129813,0.038101541,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,112533,DB00374,10042674,254,17462,68,5656,0.170707971,1.209859382,0.920758348,1.608113638,0.311807027,DB0037410042674_,1.165370785,0.19050414,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,112534,DB01240,10042674,152,5599,38,1538,0.655318173,1.0987534,0.76187026,1.619411831,0.788963159,DB0124010042674_,0.237035652,0.094176265,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,112535,DB01240,10048959,239,5512,54,1522,0.217114805,1.222071493,0.900801298,1.683258898,0.370034861,DB0124010048959_,0.994158059,0.200547364,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,112569,DB09053,10042361,20,2265,53,3999,0.141135076,0.666290332,0.376264237,1.136760496,0.271459091,DB0905310042361_,1.303943828,-0.406029769,NA,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,ibrutinib,DB09053
,112571,DB01109,10047895,57,4355,34,4236,0.026532434,1.630562273,1.045718006,2.577577415,0.076933815,DB0110910047895_,2.564809771,0.488924908,NA,10047895,Weight decreased,10022891,Investigations,Inv,heparin,DB01109
,112572,DB09053,10047895,33,2252,55,3997,0.823239656,1.064908667,0.667727116,1.674873094,0.906206603,DB0905310047895_,0.098487961,0.062889037,NA,10047895,Weight decreased,10022891,Investigations,Inv,ibrutinib,DB09053
,112650,DB01156,10051055,46,13576,26,6302,0.447013113,0.821306679,0.496616204,1.385380062,0.614783366,DB0115610051055_,0.486485324,-0.196858696,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,bupropion,DB01156
,112679,DB00480,10005722,37,67391,15,67647,0.00214985,2.476154928,1.326405629,4.856679676,0.01032313,DB0048010005722_,4.573368276,0.906706925,NA,10005722,Blood potassium abnormal,10022891,Investigations,Inv,lenalidomide,DB00480
,112681,DB14513,10062355,54,7123,31,3533,0.563235298,0.864018169,0.544469354,1.393114763,0.715297262,DB1451310062355_,0.335057072,-0.146161482,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,112698,DB01029,10003988,36,1304,17,884,0.257587079,1.43535955,0.779924177,2.743156201,0.418443663,DB0102910003988_,0.871213015,0.361415375,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,irbesartan,DB01029
,112709,DB01202,10048393,50,6664,10,5708,2.83171238853682e-06,4.282207069,2.143829643,9.479746781,3.60268926102082e-05,DB0120210048393_,10.23124488,1.454468547,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,112714,DB00169,10062355,266,38425,128,18047,0.828422945,0.976009741,0.786960642,1.215680636,0.909816664,DB0016910062355_,0.094512168,-0.024282712,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,112715,DB00213,10062355,165,18730,83,13338,0.009630567,1.415643424,1.079903605,1.867611164,0.034541781,DB0021310062355_,3.365585648,0.347584144,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,112718,DB08880,10062355,76,3262,24,785,0.250966213,0.762112263,0.472543948,1.269991568,0.410839654,DB0888010062355_,0.889552276,-0.271661408,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,teriflunomide,DB08880
,112740,DB01060,10021789,108,8479,69,5012,0.638818869,0.925217967,0.676300522,1.272984947,0.775904716,DB0106010021789_,0.253725554,-0.077725929,NA,10021789,Infection,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,112752,DB11089,10003445,40,10135,31,8376,0.812326907,1.066392162,0.649920459,1.764765484,0.899071824,DB1108910003445_,0.106392355,0.06428114,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,112754,DB01115,10003658,36,3564,26,2242,0.601876442,0.871042156,0.509963432,1.506783391,0.746048066,DB0111510003658_,0.292965249,-0.138064904,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,nifedipine,DB01115
,112769,DB01307,10020772,38,2486,28,2041,0.709693772,1.114156148,0.663437331,1.891979735,0.826838384,DB0130710020772_,0.190146027,0.1080973,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,insulin detemir,DB01307
,112772,DB00169,10021518,48,38643,6,18169,0.000627037,3.760969945,1.606963993,10.75578888,0.003737342,DB0016910021518_,5.589380536,1.324676888,female,10021518,Impaired gastric emptying,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,112782,DB01115,10040047,35,3565,30,2238,0.248773524,0.732454703,0.435503556,1.238814919,0.408173848,DB0111510040047_,0.896062096,-0.311353779,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,nifedipine,DB01115
,112787,DB01307,10047700,94,2430,40,2029,0.00028785,1.96189258,1.334622775,2.930250713,0.001950039,DB0130710047700_,6.239906067,0.673909609,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,insulin detemir,DB01307
,112788,DB09146,10047700,82,706,17,410,6.31727181869959e-05,2.799150932,1.618615892,5.1092366,0.000537986,DB0914610047700_,7.527677353,1.029316133,female,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,iron sucrose,DB09146
,112795,DB01142,10025482,61,1679,8,776,0.000183124,3.522702475,1.668753801,8.566340894,0.001338916,DB0114210025482_,6.61589472,1.259228444,female,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,doxepin,DB01142
,112830,DB00381,10058467,43,29317,32,22855,0.907499376,1.047570206,0.647392897,1.711158919,0.958758188,DB0038110058467_,0.042116386,0.046473393,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,amlodipine,DB00381
,112831,DB00451,10058467,49,47222,16,15403,1,0.998930419,0.558265707,1.882376312,1,DB0045110058467_,0,-0.001070153,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levothyroxine,DB00451
,112878,DB00019,10019303,37,18975,13,9516,0.296658593,1.427335025,0.741098185,2.927818154,0.462467892,DB0001910019303_,0.771178148,0.355809087,NA,10019303,Heart rate increased,10022891,Investigations,Inv,pegfilgrastim,DB00019
,112922,DB00181,10013710,69,9787,37,5834,0.6871081,1.111649825,0.734131719,1.707488435,0.811307667,DB0018110013710_,0.209107929,0.105845241,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,112924,DB00404,10013710,155,19737,128,9734,2.55584215863073e-05,0.597212755,0.468903963,0.761781903,0.000246082,DB0040410013710_,8.309846859,-0.515481856,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,112925,DB01202,10013710,120,6594,94,5624,0.580116215,1.088830548,0.822210627,1.445382929,0.72869727,DB0120210013710_,0.316496901,0.085104228,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,112927,DB00472,10001052,45,10714,13,4299,0.382085973,1.388868794,0.735394155,2.80948986,0.552169216,DB0047210001052_,0.593900729,0.328489599,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,112932,DB00996,10021425,43,38910,29,22396,0.540964275,0.853461714,0.520573101,1.4179504,0.696388893,DB0099610021425_,0.361847021,-0.158454595,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,gabapentin,DB00996
,112936,DB00563,10015916,79,46567,18,15330,0.194544354,1.444799493,0.857495594,2.563248504,0.342436105,DB0056310015916_,1.071670193,0.367970552,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,methotrexate,DB00563
,112938,DB00005,10049564,55,128027,16,42403,0.7835954,1.138509683,0.642864295,2.128990706,0.882171087,DB0000510049564_,0.125369266,0.129720111,NA,10049564,Impaired driving ability,10041244,Social circumstances,SocCi,etanercept,DB00005
,112954,DB00734,10025482,59,3991,38,4864,0.002043933,1.892096615,1.234725915,2.930531348,0.009897368,DB0073410025482_,4.615486462,0.637685534,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,112955,DB01065,10025482,120,4211,39,3012,9.2757213439801e-06,2.200595704,1.516681469,3.255053069,0.000101673,DB0106510025482_,9.193746802,0.788728098,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,112958,DB00624,10037844,13,549,86,4310,0.523368499,1.186675063,0.60320565,2.156466851,0.681667955,DB0062410037844_,0.383212609,0.171155332,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,testosterone,DB00624
,112959,DB01065,10037844,112,4219,59,2992,0.070798895,1.346172597,0.96992292,1.884652059,0.16270592,DB0106510037844_,1.815810879,0.297265453,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,melatonin,DB01065
,112962,DB00741,10048959,64,4030,33,3141,0.063145126,1.511486779,0.975420413,2.381832427,0.149206188,DB0074110048959_,1.902426117,0.413093788,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,112963,DB01065,10048959,63,4268,49,3002,0.629258089,0.904351474,0.610792735,1.345779624,0.768324746,DB0106510048959_,0.263542789,-0.100537195,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,112988,DB00338,10006811,45,33629,13,22259,0.006863871,2.291147053,1.214281773,4.630297076,0.026396026,DB0033810006811_,3.634541815,0.829052589,NA,10006811,Bursitis,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,112998,DB00338,10016454,101,33573,27,22245,7.75139927202836e-06,2.478512901,1.606924391,3.944569791,8.68480519459784e-05,DB0033810016454_,9.351350496,0.907658744,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,112999,DB00338,10017822,53,33621,18,22254,0.014688346,1.948922935,1.122998064,3.536362605,0.048484638,DB0033810017822_,3.026508266,0.667276879,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,113015,DB00338,10031161,158,33516,35,22237,1.1534244052239e-10,2.995033963,2.065065009,4.454366371,3.72225420396688e-09,DB0033810031161_,19.40893638,1.096955571,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,113046,DB09140,10037423,107,3634,45,1753,0.48287758,1.146975086,0.798402902,1.671104823,0.647094608,DB0914010037423_,0.43526277,0.137128117,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,113048,DB09140,10061024,61,3680,23,1775,0.349036278,1.279139449,0.777256525,2.173207052,0.518549928,DB0914010061024_,0.656718962,0.246187546,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,oxygen,DB09140
,113055,DB01238,10007515,57,5193,29,3473,0.268816147,1.314467826,0.824660554,2.13680364,0.431264186,DB0123810007515_,0.841034416,0.273431889,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,aripiprazole,DB01238
,113078,DB00207,10003553,78,9002,25,5430,0.005571845,1.88190482,1.184366214,3.086613851,0.022306897,DB0020710003553_,3.802859351,0.632284466,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,113079,DB00874,10003553,53,3282,8,1968,4.40836237392267e-05,3.9717841,1.871037802,9.695916321,0.0003971,DB0087410003553_,7.831322204,1.379215389,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,guaifenesin,DB00874
,113095,DB00213,10017944,113,18782,55,13366,0.022589515,1.462076286,1.049382911,2.058274767,0.067940431,DB0021310017944_,2.689123977,0.379857539,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,113098,DB00814,10013781,40,8247,14,3401,0.655394054,1.178239898,0.626604631,2.3478278,0.789018376,DB0081410013781_,0.236965668,0.164021713,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,113100,DB00814,10028391,64,8223,22,3393,0.551715566,1.200328949,0.728010466,2.050321395,0.705634317,DB0081410028391_,0.34865814,0.182595643,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,113102,DB00635,10053156,53,33000,17,23777,0.003314625,2.246263278,1.279872787,4.13940342,0.014665027,DB0063510053156_,4.222289735,0.809268071,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,113104,DB00005,10069826,95,127987,15,42404,0.005521974,2.098188118,1.210092517,3.896714539,0.02214772,DB0000510069826_,3.81002071,0.741074171,NA,10069826,Inflammatory marker increased,10022891,Investigations,Inv,etanercept,DB00005
,113113,DB00177,10008531,42,4758,15,2835,0.098912819,1.66824373,0.904399192,3.244762584,0.209232532,DB0017710008531_,1.564309055,0.511771414,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,113116,DB00695,10011703,38,28011,20,20508,0.287238899,1.391057301,0.789079554,2.52421218,0.452088656,DB0069510011703_,0.793876976,0.330064106,NA,10011703,Cyanosis,10047065,Vascular disorders,Vasc,furosemide,DB00695
,113117,DB00169,10019909,61,38630,40,18135,0.109023869,0.715903858,0.47254007,1.095397516,0.224592845,DB0016910019909_,1.493466093,-0.334209397,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,113119,DB00695,10019909,37,28012,35,20493,0.284457454,0.773395271,0.47367846,1.265006325,0.44895906,DB0069510019909_,0.800823576,-0.256965014,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,113123,DB00682,10005728,52,19407,28,16336,0.056699294,1.563242147,0.968742284,2.571970437,0.137289018,DB0068210005728_,1.985666953,0.446761964,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,warfarin,DB00682
,113125,DB08931,10005728,45,6532,24,2422,0.173112084,0.695261491,0.413652326,1.195827999,0.314983465,DB0893110005728_,1.155235133,-0.363467257,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,riociguat,DB08931
,113133,DB00682,10054112,485,18974,212,16152,1.21996161797824e-16,1.947408677,1.651462085,2.302648485,9.03287074043891e-15,DB0068210054112_,32.33790617,0.666499605,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,113134,DB00697,10054112,44,6052,17,1789,0.358700534,0.765122606,0.427173217,1.432066942,0.528440956,DB0069710054112_,0.6378242,-0.267719189,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,tizanidine,DB00697
,113144,DB00706,10015150,9,1066,78,15847,0.121397955,1.715216036,0.754018007,3.43882291,0.243453516,DB0070610015150_,1.412829253,0.539539041,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,tamsulosin,DB00706
,113155,DB00254,10029354,31,5904,28,3360,0.078666046,0.630083556,0.364997772,1.092305142,0.176082519,DB0025410029354_,1.736802535,-0.46190284,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,doxycycline,DB00254
,113165,DB06616,10033371,31,930,25,778,1,1.03731851,0.587185152,1.849382509,1,DB0661610033371_,0,0.036639028,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,bosutinib,DB06616
,113174,DB06605,10005557,50,14023,46,12987,1,1.006653701,0.660380584,1.537528542,1,DB0660510005557_,0,0.006631662,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,apixaban,DB06605
,113175,DB00641,10006451,171,13953,57,12418,1.24021097650919e-11,2.669731624,1.965486796,3.67325128,4.67033603403208e-10,DB0064110006451_,21.4846199,0.981977952,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,simvastatin,DB00641
,113176,DB01098,10006451,83,8066,42,7167,0.002868907,1.755864728,1.195638192,2.612927928,0.013037554,DB0109810006451_,4.339921283,0.562961458,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,rosuvastatin,DB01098
,113178,DB06605,10006451,134,13939,52,12981,2.27944866336238e-08,2.399602373,1.728265466,3.375707227,4.71588414927039e-07,DB0660510006451_,14.56715923,0.875303046,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,apixaban,DB06605
,113179,DB06605,10047895,252,13821,222,12811,0.610045612,1.052196586,0.873538958,1.268096465,0.752271771,DB0660510047895_,0.284657623,0.050879966,NA,10047895,Weight decreased,10022891,Investigations,Inv,apixaban,DB06605
,113182,DB00788,10007617,44,9312,31,5030,0.275511246,0.766718878,0.47266667,1.25760624,0.438791391,DB0078810007617_,0.823731171,-0.265635066,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,naproxen,DB00788
,113183,DB00814,10007617,37,8250,22,3393,0.195566278,0.691709359,0.396756281,1.232951065,0.343739369,DB0081410007617_,1.067871558,-0.368589413,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,meloxicam,DB00814
,113192,DB00814,10012174,68,8219,31,3384,0.657314732,0.903160745,0.58121078,1.43209778,0.790542601,DB0081410012174_,0.235035733,-0.101854729,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,meloxicam,DB00814
,113195,DB09570,10012174,80,3821,52,3883,0.013748025,1.563326662,1.085649671,2.268014902,0.045870379,DB0957010012174_,3.081935709,0.446816027,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ixazomib,DB09570
,113197,DB00215,10035226,47,11056,48,5228,0.000237189,0.46302879,0.302562805,0.708263526,0.001661209,DB0021510035226_,6.400209864,-0.769966046,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,citalopram,DB00215
,113198,DB00641,10035226,84,14040,104,12371,0.022811192,0.71169255,0.526837712,0.959031166,0.068454411,DB0064110035226_,2.681587286,-0.340109272,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,simvastatin,DB00641
,113199,DB00788,10035226,28,9328,36,5025,0.000568169,0.419012902,0.245966196,0.707079578,0.003432781,DB0078810035226_,5.674384509,-0.869853568,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,naproxen,DB00788
,113211,DB00761,10056342,36,15271,19,8606,0.88874641,1.067785337,0.596030292,1.971987279,0.953896257,DB0076110056342_,0.047200359,0.065586725,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,113213,DB00904,10056342,49,23020,21,14435,0.175862368,1.463133303,0.860777762,2.569664787,0.318475409,DB0090410056342_,1.144210015,0.380580234,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,113225,DB00316,10061169,38,65436,32,36921,0.105319184,0.67005636,0.407532316,1.108032743,0.219073571,DB0031610061169_,1.518347667,-0.400393451,NA,10061169,Embolism,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,113236,DB01234,10061169,32,31593,45,32843,0.210155325,0.739252419,0.454551772,1.189626642,0.361360201,DB0123410061169_,1.01788003,-0.302115848,NA,10061169,Embolism,10047065,Vascular disorders,Vasc,dexamethasone,DB01234
,113246,DB00996,10026749,33,38920,22,22403,0.578814602,0.863432397,0.488403654,1.554975948,0.727580497,DB0099610026749_,0.318030637,-0.146839674,NA,10026749,Mania,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,113271,DB06403,10022000,262,21209,61,6600,0.041313028,1.336553944,1.006580168,1.798915106,0.108358324,DB0640310022000_,2.22231173,0.290094618,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,113273,DB00193,10013781,114,19206,32,8670,0.015502912,1.608164056,1.077306562,2.462890239,0.050579537,DB0019310013781_,2.984208183,0.47509319,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,113277,DB00924,10013781,75,10087,19,4232,0.053213351,1.656066328,0.989112975,2.90593434,0.131057666,DB0092410013781_,2.032117856,0.504445108,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,113299,DB00153,10048393,52,7371,13,3426,0.044738951,1.859084539,0.996559301,3.726825062,0.115070534,DB0015310048393_,2.16221,0.620084183,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,113300,DB00571,10048393,47,5076,9,2600,0.004235904,2.674615053,1.293213588,6.217350761,0.017894688,DB0057110048393_,4.023251363,0.983805464,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,propranolol,DB00571
,113301,DB00588,10048393,91,16433,10,8458,3.45279725825642e-08,4.684166445,2.432195702,10.10134294,6.88855984313245e-07,DB0058810048393_,14.18823361,1.54418798,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,113304,DB00316,10051290,59,65415,18,36935,0.023446456,1.850706371,1.076277464,3.334721047,0.069921726,DB0031610051290_,2.660378866,0.615567389,NA,10051290,Central nervous system lesion,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,113309,DB00996,10051290,59,38894,18,22407,0.01742454,1.888322124,1.097997822,3.402995232,0.055457619,DB0099610051290_,2.892136173,0.63568867,NA,10051290,Central nervous system lesion,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,113328,DB00287,10013573,40,1361,19,798,0.496415249,1.234236883,0.692769765,2.272892484,0.658588004,DB0028710013573_,0.417657123,0.21045287,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,travoprost,DB00287
,113329,DB01162,10013573,8,265,76,1626,0.330694294,0.646004444,0.266106828,1.35935855,0.499413933,DB0116210013573_,0.694320001,-0.436948896,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,terazosin,DB01162
,113350,DB00421,10006784,38,8865,17,5235,0.402150081,1.31997105,0.726381155,2.496528199,0.571966607,DB0042110006784_,0.558674668,0.277609805,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,113351,DB00695,10006784,107,27942,58,20470,0.069351549,1.351490965,0.972298012,1.894976162,0.160163095,DB0069510006784_,1.831562637,0.301208402,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,113352,DB00203,10017885,114,13764,56,8882,0.098118822,1.313643547,0.944815091,1.844763407,0.208013327,DB0020310017885_,1.570153131,0.27280461,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,113353,DB00421,10017885,112,8791,23,5229,3.75421708939275e-07,2.896285753,1.83409341,4.761679756,5.97153380905829e-06,DB0042110017885_,12.02850674,1.063429141,female,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,113354,DB00559,10017885,65,9594,13,3293,0.08919794,1.716027914,0.93532062,3.398607779,0.193958294,DB0055910017885_,1.640112124,0.540012268,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,bosentan,DB00559
,113355,DB00421,10061024,84,8819,76,5176,0.008235522,0.648743038,0.46899478,0.89850036,0.030489754,DB0042110061024_,3.490364596,-0.432718576,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,spironolactone,DB00421
,113358,DB00695,10037324,61,27988,11,20517,1.71501287566449e-06,4.065045757,2.119317287,8.570319395,2.31471699290583e-05,DB0069510037324_,10.67363803,1.402424999,female,10037324,Pulmonary arterial pressure increased,10022891,Investigations,Inv,furosemide,DB00695
,113362,DB01050,10002424,39,18069,33,9338,0.045560323,0.610751402,0.374031052,1.002843289,0.11663931,DB0105010002424_,2.148668925,-0.493065274,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,113366,DB06724,10037844,221,7708,91,3828,0.143540634,1.20604882,0.937578399,1.561964027,0.274857258,DB0672410037844_,1.291503379,0.187349578,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,calcium carbonate,DB06724
,113367,DB01281,10033425,153,8779,24,1774,0.309477589,1.28818629,0.831182699,2.07870897,0.476949865,DB0128110033425_,0.740343898,0.253235252,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,abatacept,DB01281
,113370,DB01281,10052904,86,8846,15,1783,0.689055451,1.155595598,0.661224581,2.159036042,0.81249806,DB0128110052904_,0.207641753,0.14461588,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,abatacept,DB01281
,113371,DB00158,10003658,140,16675,104,8000,0.000946757,0.645831758,0.496823972,0.841788722,0.005263934,DB0015810003658_,5.246876599,-0.437216246,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,folic acid,DB00158
,113372,DB01020,10003658,33,1780,44,1834,0.300288902,0.772808429,0.474347252,1.248094554,0.466453553,DB0102010003658_,0.762596829,-0.25772409,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,isosorbide mononitrate,DB01020
,113408,DB01076,10003997,18,25729,32,25551,0.048105928,0.558618223,0.29517037,1.025966745,0.121542203,DB0107610003997_,2.107493726,-0.582289004,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,113417,DB00169,10006093,64,38627,62,18113,7.31658027198237e-05,0.484040778,0.335838026,0.69813871,0.00060956,DB0016910006093_,7.402772484,-0.725586125,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,113418,DB01020,10006093,32,1781,20,1858,0.092790643,1.66893357,0.921748296,3.091525135,0.199697224,DB0102010006093_,1.61095294,0.512184842,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,isosorbide mononitrate,DB01020
,113419,DB01118,10006093,70,2993,94,4615,0.419397144,1.148221719,0.827391168,1.587222278,0.588414538,DB0111810006093_,0.530323583,0.138214414,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,amiodarone,DB01118
,113426,DB01020,10013573,68,1745,81,1797,0.403660959,0.86455771,0.612598658,1.217080933,0.573355398,DB0102010013573_,0.556249514,-0.145537221,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,isosorbide mononitrate,DB01020
,113429,DB10631,10013573,44,1252,6,205,0.836639317,1.200607992,0.500974814,3.491897738,0.915625842,DB1063110013573_,0.088147467,0.182828088,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,cranberry,DB10631
,113432,DB00169,10013887,72,38619,53,18122,0.015987662,0.63747111,0.440715374,0.927255378,0.051801011,DB0016910013887_,2.960345609,-0.45024632,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,113435,DB01076,10013887,63,25684,67,25516,0.725876616,0.934120158,0.651307561,1.338398816,0.839460011,DB0107610013887_,0.174996438,-0.0681502,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,113455,DB00169,10063829,36,38655,22,18153,0.3269507,0.768436017,0.439860414,1.371711595,0.495363844,DB0016910063829_,0.702462748,-0.263397977,NA,10063829,Device malfunction,10077536,Product issues,Prod,cholecalciferol,DB00169
,113456,DB00381,10063829,39,29321,19,22868,0.111410979,1.600869247,0.902803905,2.933889209,0.22816031,DB0038110063829_,1.477706784,0.470546761,NA,10063829,Device malfunction,10077536,Product issues,Prod,amlodipine,DB00381
,113459,DB01076,10063829,43,25704,28,25555,0.095814461,1.526791553,0.926681086,2.552964002,0.204492437,DB0107610063829_,1.587224287,0.42316851,NA,10063829,Device malfunction,10077536,Product issues,Prod,atorvastatin,DB01076
,113469,DB00682,10016454,48,19411,17,16347,0.001644782,2.377718118,1.342341206,4.412170555,0.008283692,DB0068210016454_,4.79346651,0.866141254,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,113471,DB08932,10018964,139,19304,71,6526,0.006566227,0.661856634,0.493049131,0.895094791,0.025448727,DB0893210018964_,3.671089556,-0.412706312,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,113472,DB00374,10020100,61,17655,10,5714,0.05144135,1.974098417,1.002962093,4.325087831,0.127734721,DB0037410020100_,2.057799658,0.680111796,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,113483,DB00203,10047942,35,13843,38,8900,0.030016098,0.592201459,0.362944841,0.963673267,0.084744698,DB0020310047942_,2.468112091,-0.5239084,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,sildenafil,DB00203
,113484,DB08932,10047942,50,19393,19,6578,0.678132885,0.892608434,0.516612586,1.604402445,0.805000469,DB0893210047942_,0.216912419,-0.113607278,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,macitentan,DB08932
,113487,DB00682,10000891,32,19427,41,16323,0.078000604,0.655798481,0.399543676,1.067759091,0.17500285,DB0068210000891_,1.74295302,-0.421901732,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,warfarin,DB00682
,113488,DB01234,10000891,42,31583,57,32831,0.19269097,0.765963409,0.501407359,1.161665752,0.340016256,DB0123410000891_,1.078761852,-0.266620879,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,113528,DB01015,10042033,37,9850,66,9315,0.002048459,0.530178089,0.344201117,0.805620077,0.009915347,DB0101510042033_,4.613671558,-0.634542313,NA,10042033,Stevens-Johnson syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,113538,DB01590,10001760,47,4691,10,2857,0.001392888,2.862136814,1.424518837,6.363010769,0.007230585,DB0159010001760_,4.929435324,1.051568484,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,everolimus,DB01590
,113540,DB00425,10048334,46,12649,13,7471,0.015241889,2.08988431,1.109334223,4.219388595,0.04993868,DB0042510048334_,2.996959426,0.737108711,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,113541,DB00695,10048334,103,27946,44,20484,0.002508389,1.715827067,1.193866527,2.502334358,0.011690247,DB0069510048334_,4.449000379,0.539895219,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,113543,DB08908,10048334,133,10540,46,3233,0.478535124,0.886859931,0.628229505,1.271748634,0.643819201,DB0890810048334_,0.440337336,-0.120068223,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,dimethyl fumarate,DB08908
,113544,DB00695,10048393,90,27959,10,20518,1.53284188567148e-12,6.604017979,3.429334592,14.24542909,6.67618044157e-11,DB0069510048393_,23.42988999,1.887678248,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,113546,DB00264,10061520,58,29549,30,24862,0.031935501,1.626653642,1.029243653,2.619724039,0.088967796,DB0026410061520_,2.419480819,0.486524924,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,113548,DB00695,10061520,47,28002,29,20499,0.488237932,1.186416046,0.731117323,1.955584734,0.651821628,DB0069510061520_,0.427984331,0.170937036,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,113554,DB14500,10061818,72,7737,51,4022,0.104162854,0.733940584,0.504527775,1.074440494,0.217295286,DB1450010061818_,1.526498084,-0.309327202,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,113570,DB00480,10003986,43,67385,38,67624,0.580390014,1.135590662,0.7167553,1.805666505,0.728953804,DB0048010003986_,0.316144919,0.127152923,NA,10003986,Back injury,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,113571,DB00497,10028035,38,19229,14,16361,0.007538916,2.309334171,1.222625041,4.615770891,0.028403987,DB0049710028035_,3.561225752,0.836959245,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,113573,DB00921,10033425,40,5805,31,4872,0.811380706,1.082957316,0.659526625,1.793425404,0.898590302,DB0092110033425_,0.106928075,0.079695555,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,buprenorphine,DB00921
,113575,DB00043,10033775,72,6341,19,2281,0.281557577,1.363084995,0.811002587,2.399343449,0.445492305,DB0004310033775_,0.808575305,0.30975051,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,omalizumab,DB00043
,113587,DB01306,10016322,59,4149,40,3826,0.156221043,1.360116286,0.892837407,2.091142701,0.292386769,DB0130610016322_,1.229677802,0.3075702,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,113592,DB06626,10010774,20,668,30,1422,0.224621733,1.418950521,0.75770841,2.604363809,0.379299901,DB0662610010774_,0.969428092,0.349917529,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,axitinib,DB06626
,113598,DB06643,10018280,75,52346,9,7506,0.742065771,1.19490013,0.596639683,2.715467676,0.852146128,DB0664310018280_,0.159997256,0.178062608,NA,10018280,Gingival disorder,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,113599,DB00264,10033433,104,29503,39,24853,7.00167307076094e-06,2.246282111,1.540235324,3.336000871,7.94470005028929e-05,DB0026410033433_,9.440420419,0.809276455,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,113603,DB00264,10044055,43,29564,13,24879,0.000676165,2.78337751,1.468753376,5.64350979,0.003979178,DB0026410044055_,5.526680113,1.023665122,female,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,113612,DB00046,10017577,55,5404,41,4651,0.537629349,1.154525521,0.755008843,1.778006852,0.693745088,DB0004610017577_,0.365650695,0.143689455,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,113613,DB00046,10038428,27,5432,38,4654,0.060407713,0.608797864,0.356869417,1.025379072,0.144179269,DB0004610038428_,1.936697828,-0.496268982,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,insulin lispro,DB00046
,113615,DB01136,10038428,62,9822,59,11056,0.362634299,1.182860372,0.813769585,1.720931293,0.532207848,DB0113610038428_,0.630721175,0.167935549,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,carvedilol,DB01136
,113625,DB00060,10067484,89,9419,17,2448,0.27833824,1.36061438,0.802016921,2.443863793,0.442155177,DB0006010067484_,0.816094379,0.307936348,NA,10067484,Adverse reaction,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,113626,DB08908,10067484,63,10610,18,3261,0.895580684,1.075724219,0.627803113,1.933428742,0.95615204,DB0890810067484_,0.044838341,0.072994127,NA,10067484,Adverse reaction,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,113628,DB00051,10020937,316,25415,140,11280,1,1.001793141,0.817420307,1.232843775,1,DB0005110020937_,0,0.001791535,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,113630,DB08910,10005191,41,16703,24,17464,0.025054478,1.786123022,1.053425383,3.092115112,0.073573561,DB0891010005191_,2.609469547,0.580047362,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,pomalidomide,DB08910
,113631,DB08910,10008531,46,16698,40,17448,0.449901874,1.201644426,0.768993848,1.884853932,0.617544623,DB0891010008531_,0.482003949,0.183690974,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,113633,DB08910,10040844,29,16715,37,17451,0.460601804,0.818301511,0.485144807,1.368033996,0.627974638,DB0891010040844_,0.465255498,-0.200524415,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,pomalidomide,DB08910
,113641,DB00331,10023547,84,24862,71,20681,0.935732081,0.984136326,0.708539263,1.370247619,0.975904366,DB0033110023547_,0.024390683,-0.015990849,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,metformin,DB00331
,113642,DB00476,10023547,37,17220,25,6152,0.01979539,0.528787018,0.30961956,0.917165632,0.061304487,DB0047610023547_,2.791902243,-0.63716954,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,duloxetine,DB00476
,113645,DB08889,10023547,35,3130,51,3834,0.447359714,0.840652387,0.52915509,1.321819479,0.615131308,DB0888910023547_,0.485919524,-0.173577038,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,carfilzomib,DB08889
,113648,DB00678,10000060,95,15504,66,10658,1,0.989488916,0.714491014,1.377306331,1,DB0067810000060_,0,-0.010566716,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,113649,DB00829,10000060,46,8006,18,4436,0.239732163,1.415956178,0.80411584,2.598014541,0.397549597,DB0082910000060_,0.922435579,0.347805047,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,diazepam,DB00829
,113650,DB01015,10000060,60,9827,48,9333,0.386684853,1.18715123,0.797761432,1.774963822,0.556794837,DB0101510000060_,0.585558443,0.171556513,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,113661,DB01039,10000081,50,2923,34,3017,0.062445543,1.517766585,0.959226302,2.427837796,0.148012183,DB0103910000081_,1.91046069,0.417239902,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,fenofibrate,DB01039
,113679,DB00316,10003210,32,65442,23,36930,0.40043837,0.785153598,0.445238705,1.405295774,0.570272664,DB0031610003210_,0.561640674,-0.241875915,NA,10003210,Arteriosclerosis,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,113688,DB01118,10003239,25,3038,37,4672,0.896685507,1.039113985,0.598255437,1.777068412,0.956301489,DB0111810003239_,0.044682051,0.038368413,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,amiodarone,DB01118
,113689,DB00264,10003662,57,29550,92,24800,9.67097301673807e-05,0.519986113,0.366777444,0.731712717,0.000774053,DB0026410003662_,7.163870074,-0.653953173,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,metoprolol,DB00264
,113690,DB00316,10003662,60,65414,66,36887,0.000189051,0.512626139,0.355179855,0.738635841,0.001374229,DB0031610003662_,6.58986256,-0.668208473,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,113691,DB00338,10003662,31,33643,38,22234,0.013249695,0.539161785,0.324285955,0.890112966,0.044540564,DB0033810003662_,3.11135496,-0.617739596,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,omeprazole,DB00338
,113698,DB00316,10005395,72,65402,45,36908,0.630265985,0.902923661,0.613526478,1.341406046,0.769213047,DB0031610005395_,0.262387303,-0.102117268,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,113701,DB00996,10005395,46,38907,18,22407,0.193922284,1.471765483,0.836755105,2.697621226,0.341615659,DB0099610005395_,1.074068979,0.386462689,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,gabapentin,DB00996
,113705,DB01015,10006784,34,9853,21,9360,0.137333988,1.537997188,0.866581199,2.790822043,0.266005222,DB0101510006784_,1.32423934,0.430481042,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,113714,DB06643,10010214,83,52338,6,7509,0.109138841,1.984665795,0.873754947,5.565187152,0.224735979,DB0664310010214_,1.492828992,0.685450535,NA,10010214,Compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,113722,DB00316,10016766,204,65270,108,36845,0.636775819,1.066285217,0.840064342,1.359626163,0.774232199,DB0031610016766_,0.255883452,0.064180848,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,113726,DB00829,10017577,129,7923,44,4410,0.004996661,1.631811892,1.148135235,2.357865016,0.020457438,DB0082910017577_,3.88940877,0.489690987,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,113727,DB01039,10017577,50,2923,22,3029,0.000780701,2.354835222,1.395869772,4.094608112,0.004482957,DB0103910017577_,5.407472455,0.856470756,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,113738,DB00338,10018092,32,33642,18,22254,0.665438779,1.175951055,0.640329552,2.225734213,0.796460011,DB0033810018092_,0.227578356,0.162077229,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,113741,DB00996,10018092,31,38922,23,22402,0.396598135,0.775775975,0.437757284,1.393548985,0.566170933,DB0099610018092_,0.568859244,-0.253891492,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,113749,DB00338,10029223,83,33591,40,22232,0.11661227,1.373317933,0.930517991,2.056869227,0.23604432,DB0033810029223_,1.443735697,0.317229661,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,113755,DB00678,10033775,152,15447,81,10643,0.070373554,1.292927398,0.979821001,1.716697715,0.161954986,DB0067810033775_,1.820436848,0.256908948,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,losartan,DB00678
,113756,DB00829,10033775,108,7944,40,4414,0.030600038,1.500180692,1.032628302,2.21802483,0.086023743,DB0082910033775_,2.453131935,0.405585562,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,113757,DB01015,10033775,79,9808,75,9306,1,0.999420908,0.718370268,1.391458467,1,DB0101510033775_,0,-0.00057926,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,113769,DB00678,10035598,75,15524,55,10669,0.721152081,0.937173308,0.652383106,1.353638533,0.835521773,DB0067810035598_,0.179698872,-0.064887054,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,113770,DB01015,10035598,73,9814,79,9302,0.416889606,0.875849329,0.62744354,1.22118525,0.586065824,DB0101510035598_,0.534323168,-0.132561201,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,113772,DB06643,10035598,56,52365,17,7498,0.011600407,0.471681113,0.269930459,0.866418715,0.040086333,DB0664310035598_,3.216719837,-0.75145213,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,denosumab,DB06643
,113777,DB00678,10037423,68,15531,34,10690,0.131200266,1.376584563,0.898515108,2.144987924,0.257531103,DB0067810037423_,1.356614779,0.319605477,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,113779,DB01015,10037423,43,9844,40,9341,1,1.02007219,0.646989164,1.611602966,1,DB0101510037423_,0,0.019873399,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,113781,DB01118,10037423,31,3032,48,4661,1,0.992820441,0.609398293,1.596132271,1,DB0111810037423_,0,-0.007205456,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,113783,DB00316,10038423,35,65439,15,36938,0.461691175,1.317084268,0.700805215,2.596083303,0.628915451,DB0031610038423_,0.46375845,0.275420405,NA,10038423,Renal cyst,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,113793,DB00996,10041101,54,38899,37,22388,0.446000097,0.83999013,0.542560709,1.313285309,0.613855874,DB0099610041101_,0.487995112,-0.174365137,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,113802,DB01118,10046571,76,2987,35,4674,7.88481705005938e-10,3.397268295,2.241587376,5.239737178,2.23452739796022e-08,DB0111810046571_,17.61665099,1.222971666,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,amiodarone,DB01118
,113803,DB00338,10047302,35,33639,26,22246,0.69526083,0.890236557,0.520609083,1.540452021,0.816560818,DB0033810047302_,0.202653883,-0.116268057,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,omeprazole,DB00338
,113808,DB01118,10047302,57,3006,104,4605,0.328192518,0.839657997,0.594877818,1.174937783,0.49679175,DB0111810047302_,0.699584355,-0.174760616,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,amiodarone,DB01118
,113819,DB00338,10048706,52,33622,8,22264,1.43678448711355e-05,4.304104656,2.029996177,10.49543435,0.000149449,DB0033810048706_,8.808552237,1.459569139,female,10048706,Joint range of motion decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,113822,DB00996,10048706,54,38899,13,22412,0.003240193,2.393241076,1.288596439,4.781467344,0.014403596,DB0099610048706_,4.240277383,0.872648546,NA,10048706,Joint range of motion decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,113899,DB00559,10052264,69,9590,25,3281,0.812493679,0.944270798,0.58869004,1.560414774,0.899178829,DB0055910052264_,0.106273345,-0.057342291,NA,10052264,Catheter site erythema,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,113900,DB00158,10022052,196,16619,38,8066,2.10874488652433e-08,2.503294161,1.759411965,3.647068886,4.39907613827714e-07,DB0015810022052_,14.6367011,0.917607529,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,113901,DB01373,10022052,106,22614,8,7373,1.7276804742024e-06,4.319939668,2.113012262,10.27108778,2.32822769876494e-05,DB0137310022052_,10.66781813,1.463241437,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,113916,DB00338,10037855,72,33602,42,22230,0.566020373,1.134145188,0.764373097,1.701841988,0.717471391,DB0033810037855_,0.332022205,0.125879229,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,113919,DB00996,10037884,112,38841,64,22361,1,1.007485615,0.734225902,1.392635242,1,DB0099610037884_,0,0.007457737,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,113921,DB09053,10043554,32,2253,73,3979,0.259887747,0.77420097,0.492660058,1.192585695,0.421142963,DB0905310043554_,0.864782924,-0.255923788,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,ibrutinib,DB09053
,113924,DB01175,10005750,76,10648,44,4848,0.235455759,0.786462958,0.534653247,1.169311431,0.39258807,DB0117510005750_,0.934994385,-0.240209655,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,escitalopram,DB01175
,113950,DB00370,10008190,37,4504,19,3644,0.137215827,1.575447711,0.881339835,2.905510283,0.265844919,DB0037010008190_,1.324842152,0.454539493,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,mirtazapine,DB00370
,113952,DB01156,10008190,51,13571,36,6292,0.063981503,0.656825171,0.419936198,1.037163798,0.150620555,DB0115610008190_,1.892991484,-0.420337398,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,113953,DB00921,10010264,49,5796,34,4869,0.439249626,1.210655563,0.764537705,1.937199076,0.607635199,DB0092110010264_,0.498180579,0.191162,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,113954,DB01156,10020642,145,13477,66,6262,0.940775999,1.020820577,0.756697029,1.389454882,0.980037141,DB0115610020642_,0.020164809,0.020606791,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,bupropion,DB01156
,113960,DB00370,10037660,81,4460,62,3601,0.799286126,1.054833152,0.746109687,1.497529634,0.891581897,DB0037010037660_,0.114757982,0.053382604,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,113961,DB00921,10037660,33,5812,24,4879,0.689560145,1.1542553,0.660813021,2.04406063,0.812875364,DB0092110037660_,0.207177486,0.143455374,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,113963,DB00921,10043071,43,5802,16,4887,0.005455238,2.26345127,1.247415209,4.310528016,0.021928573,DB0092110043071_,3.819964781,0.816890759,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,buprenorphine,DB00921
,113976,DB00860,10013700,46,1837,9,1487,1.40702937215655e-05,4.135802835,1.991919757,9.645363514,0.000146703,DB0086010013700_,8.827102025,1.419681466,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,prednisolone,DB00860
,113978,DB00678,10000891,41,15558,56,10668,0.000845148,0.5020297,0.326888667,0.765279862,0.004790753,DB0067810000891_,5.341067773,-0.689095998,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,losartan,DB00678
,114001,DB00619,10013968,57,2842,66,2428,0.100093551,0.737875879,0.506212164,1.072726963,0.210915423,DB0061910013968_,1.556298067,-0.303979655,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,imatinib,DB00619
,114003,DB01394,10013968,112,1328,75,1928,3.79769087858312e-07,2.16755761,1.589426963,2.969314487,6.03520584906635e-06,DB0139410013968_,12.01790059,0.773601008,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,colchicine,DB01394
,114004,DB04868,10013968,66,1575,62,1454,0.928318892,0.982736817,0.678909525,1.423972888,0.970147351,DB0486810013968_,0.030307311,-0.017413929,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nilotinib,DB04868
,114006,DB01394,10019211,81,1359,38,1965,6.41167761093078e-09,3.081077313,2.056968304,4.687206746,1.50474058931532e-07,DB0139410019211_,15.70947513,1.125279313,female,10019211,Headache,10029205,Nervous system disorders,Nerv,colchicine,DB01394
,114007,DB01591,10019211,80,1875,11,645,0.002890842,2.500982399,1.31487606,5.243869811,0.013113433,DB0159110019211_,4.33411815,0.916683614,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,solifenacin,DB01591
,114008,DB00619,10033425,53,2846,41,2453,0.676633959,1.114134234,0.724376649,1.724426962,0.803963008,DB0061910033425_,0.218202021,0.108077632,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,imatinib,DB00619
,114010,DB01394,10033425,56,1384,34,1969,8.50970225217232e-05,2.342678844,1.494038545,3.721631213,0.000695515,DB0139410033425_,7.270858428,0.85129508,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,colchicine,DB01394
,114028,DB00678,10042772,108,15491,107,10617,0.007970815,0.691795522,0.52392733,0.913516464,0.029705498,DB0067810042772_,3.516423148,-0.368464856,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,losartan,DB00678
,114029,DB01115,10042772,41,3559,26,2242,1,0.993386402,0.591394096,1.696465598,1,DB0111510042772_,0,-0.006635565,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,nifedipine,DB01115
,114039,DB08896,10017577,42,781,53,987,1,1.001472918,0.644307337,1.548233577,1,DB0889610017577_,0,0.001471834,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,regorafenib,DB08896
,114055,DB00203,10022595,52,13826,27,8911,0.419340082,1.241245686,0.76482442,2.057176819,0.588376655,DB0020310022595_,0.530387967,0.216115461,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,sildenafil,DB00203
,114057,DB00787,10046571,316,16684,134,17114,5.66240138209504e-19,2.419005094,1.967945499,2.986607702,5.33463155298811e-17,DB0078710046571_,37.46972676,0.883356338,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,acyclovir,DB00787
,114084,DB01296,10028813,76,1373,35,948,0.05957034,1.499041385,0.982600054,2.326269219,0.142665136,DB0129610028813_,1.947255104,0.404825827,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,glucosamine,DB01296
,114091,DB09570,10016173,103,3798,53,3882,4.59824057999967e-05,1.986196171,1.40798569,2.830176474,0.000411035,DB0957010016173_,7.796832918,0.686221338,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ixazomib,DB09570
,114094,DB00480,10016454,110,67318,77,67585,0.01564425,1.434226956,1.061954839,1.945257986,0.050948966,DB0048010016454_,2.976930809,0.360625997,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,114095,DB00641,10016454,41,14083,21,12454,0.041767406,1.726506091,0.996292715,3.077276328,0.109261173,DB0064110016454_,2.21401418,0.546099766,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,114098,DB01234,10016454,48,31577,32,32856,0.056763804,1.560735032,0.977126014,2.523448751,0.137362971,DB0123410016454_,1.985128432,0.445156885,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,114111,DB01115,10003239,84,3516,30,2238,0.006356909,1.782087383,1.157545238,2.811424989,0.024802043,DB0111510003239_,3.696829246,0.577785364,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,nifedipine,DB01115
,114112,DB00471,10003246,90,14099,8,5457,2.20909794001565e-06,4.354270745,2.115703612,10.40089581,2.89534476954931e-05,DB0047110003246_,10.44982127,1.471157144,female,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,114113,DB00588,10003246,105,16419,20,8448,1.01801891867726e-05,2.701167706,1.662052455,4.605046724,0.000110299,DB0058810003246_,9.112312339,0.993684163,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,114114,DB00820,10003246,59,11856,22,5794,0.342500806,1.310624289,0.790181573,2.248538343,0.511804075,DB0082010003246_,0.669813393,0.27050358,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,114122,DB00471,10024855,93,14096,36,5429,1,0.994957415,0.66950528,1.50737872,1,DB0047110024855_,0,-0.005055341,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,114130,DB00060,10029148,45,9463,15,2450,0.422683391,0.776727129,0.424091164,1.502785338,0.591614949,DB0006010029148_,0.52489928,-0.252666175,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,interferon beta-1a,DB00060
,114131,DB09020,10016256,122,1832,92,1512,0.570921473,1.09439394,0.82064869,1.463543227,0.721353182,DB0902010016256_,0.326626412,0.090200731,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,bisacodyl,DB09020
,114132,DB00788,10017577,158,9198,64,4997,0.055443299,1.341172359,0.994860356,1.826208205,0.135063655,DB0078810017577_,2.002009096,0.293544127,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,114133,DB01069,10017577,100,6600,17,2378,0.002913015,2.119335847,1.256279956,3.790078833,0.01318784,DB0106910017577_,4.328460118,0.75110276,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,114134,DB01069,10019063,41,6659,14,2381,1,1.047110788,0.558004884,2.083779844,1,DB0106910019063_,0,0.046034741,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,promethazine,DB01069
,114148,DB00316,10057667,39,65435,20,36933,0.787369052,1.100634935,0.626411143,1.991984135,0.884765643,DB0031610057667_,0.122432479,0.095887227,NA,10057667,Bipolar disorder,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,114156,DB00745,10047895,59,2518,30,1053,0.410801475,0.822507342,0.518004582,1.330561536,0.580143351,DB0074510047895_,0.544480049,-0.19539787,NA,10047895,Weight decreased,10022891,Investigations,Inv,modafinil,DB00745
,114175,DB00829,10009033,40,8012,11,4443,0.039666197,2.016419139,1.014141354,4.361949385,0.104992295,DB0082910009033_,2.25386831,0.701323235,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diazepam,DB00829
,114177,DB00829,10046306,38,8014,19,4435,0.782714782,1.1068166,0.62155548,2.035155207,0.881806742,DB0082910046306_,0.12578236,0.101487967,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,diazepam,DB00829
,114202,DB00211,10016173,94,1342,140,1491,0.034726956,0.746048859,0.562199819,0.986548022,0.094910115,DB0021110016173_,2.35482499,-0.292964186,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,midodrine,DB00211
,114218,DB00338,10056812,76,33598,40,22232,0.255661279,1.257224972,0.846097497,1.893426647,0.416402077,DB0033810056812_,0.876103954,0.228906889,NA,10056812,Body height decreased,10022891,Investigations,Inv,omeprazole,DB00338
,114219,DB00399,10056812,40,6952,37,4961,0.296642237,0.771492749,0.480160218,1.242523319,0.462456108,DB0039910056812_,0.771203628,-0.259428006,NA,10056812,Body height decreased,10022891,Investigations,Inv,zoledronic acid,DB00399
,114225,DB00678,10056812,45,15554,15,10709,0.01240691,2.065451336,1.129362877,3.991369148,0.042270731,DB0067810056812_,3.163660381,0.725348767,NA,10056812,Body height decreased,10022891,Investigations,Inv,losartan,DB00678
,114227,DB00787,10056812,53,16947,65,17183,0.311897431,0.826745235,0.563758478,1.207679464,0.479330194,DB0078710056812_,0.735365578,-0.190258691,NA,10056812,Body height decreased,10022891,Investigations,Inv,acyclovir,DB00787
,114249,DB00758,10018964,38,8262,94,9980,0.00014218,0.488342757,0.325470384,0.719822707,0.001077621,DB0075810018964_,6.8329998,-0.716737748,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,114251,DB00758,10028735,54,8246,36,10038,0.005531546,1.825890777,1.174490608,2.869031772,0.022177651,DB0075810028735_,3.808670195,0.602067965,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,114252,DB01136,10028735,65,9819,34,11081,0.000243751,2.15741327,1.402458669,3.373064459,0.001697894,DB0113610028735_,6.378366659,0.768909944,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,114254,DB00331,10029410,48,24898,41,20711,0.915480731,0.973847075,0.628209425,1.515873512,0.962143444,DB0033110029410_,0.03859173,-0.026500995,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,114258,DB00758,10035598,50,8250,61,10013,1,0.994833736,0.669716527,1.471772344,1,DB0075810035598_,0,-0.005179655,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,114266,DB00758,10039101,53,8247,48,10026,0.160233103,1.342319691,0.890045805,2.028865238,0.297806408,DB0075810039101_,1.211311642,0.29439923,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,114267,DB01136,10039101,55,9829,31,11084,0.00224679,2.000644792,1.264446748,3.217541043,0.010694836,DB0113610039101_,4.537994265,0.693469525,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,114282,DB00331,10055798,83,24863,60,20692,0.449222068,1.151257608,0.815565226,1.633490432,0.616834119,DB0033110055798_,0.483155142,0.140854917,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,metformin,DB00331
,114296,DB09270,10016256,322,2792,217,2151,0.155792755,1.143163997,0.95042258,1.376956188,0.291854648,DB0927010016256_,1.23149938,0.133799854,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,114306,DB01065,10022437,146,4185,91,2960,0.383530677,1.134715225,0.863563427,1.497560079,0.55354389,DB0106510022437_,0.591414235,0.126381716,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,melatonin,DB01065
,114309,DB09270,10022437,78,3036,53,2315,0.53364318,1.122137987,0.778072102,1.629238632,0.690295816,DB0927010022437_,0.370635055,0.115235783,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ubidecarenone,DB09270
,114321,DB01065,10047895,98,4233,47,3004,0.032882062,1.479644171,1.031200794,2.149137096,0.091032175,DB0106510047895_,2.396542261,0.391801634,NA,10047895,Weight decreased,10022891,Investigations,Inv,melatonin,DB01065
,114331,DB01065,10053762,124,4207,113,2938,0.044515222,0.766379271,0.586425204,1.002366072,0.114618466,DB0106510053762_,2.166146351,-0.266078099,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,melatonin,DB01065
,114334,DB00169,10054786,41,38650,21,18154,0.785490539,0.917042127,0.529349811,1.633974729,0.883669115,DB0016910054786_,0.12367259,-0.086601868,NA,10054786,Skin burning sensation,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,114341,DB01065,10061428,86,4245,67,2984,0.561714429,0.902301021,0.64562406,1.265535046,0.714032538,DB0106510061428_,0.336826746,-0.102807088,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,melatonin,DB01065
,114353,DB00264,10051077,21,29586,32,24860,0.037883191,0.551435162,0.302125246,0.986520497,0.101416681,DB0026410051077_,2.288517692,-0.595231013,NA,10051077,Post procedural haemorrhage,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,114361,DB00588,10041349,197,16327,66,8402,0.002519442,1.536001349,1.155190499,2.064601892,0.011729362,DB0058810041349_,4.445659992,0.429182513,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,114365,DB08931,10024855,156,6421,72,2374,0.131207668,0.801068974,0.599564872,1.07886629,0.257531759,DB0893110024855_,1.356612232,-0.221808226,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,114366,DB08931,10060933,68,6509,27,2419,0.816506753,0.935982446,0.589615657,1.524785784,0.901759664,DB0893110060933_,0.103407242,-0.066158557,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,114368,DB00115,10013971,91,18334,59,10413,0.443887294,0.876016328,0.623833244,1.238235764,0.611877887,DB0011510013971_,0.491222548,-0.132370549,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,114370,DB00115,10016322,363,18062,153,10319,0.00165385,1.355447036,1.117242885,1.650911824,0.008319892,DB0011510016322_,4.789105956,0.304131315,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,114373,DB00115,10062237,67,18358,48,10424,0.243334486,0.792599973,0.538565763,1.174230224,0.40166884,DB0011510062237_,0.91212731,-0.232436632,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,cyanocobalamin,DB00115
,114377,DB00982,10060795,35,3329,29,2072,0.301007484,0.751238863,0.444563835,1.278260392,0.467293608,DB0098210060795_,0.760797508,-0.286031618,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,isotretinoin,DB00982
,114379,DB08932,10021015,93,19350,33,6564,0.837388785,0.955995762,0.635692899,1.470188154,0.916179909,DB0893210021015_,0.087542527,-0.045001799,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,macitentan,DB08932
,114389,DB01076,10005839,29,25718,47,25536,0.038844116,0.61266433,0.371716662,0.994171309,0.103323224,DB0107610005839_,2.269893107,-0.489938078,NA,10005839,Blood triglycerides increased,10022891,Investigations,Inv,atorvastatin,DB01076
,114391,DB00051,10008190,114,25617,89,11331,9.04206157832224e-05,0.566603991,0.425229018,0.756937727,0.000732421,DB0005110008190_,7.219155182,-0.568094649,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,114392,DB00571,10008190,35,5088,18,2591,1,0.990182135,0.544581442,1.860947743,1,DB0057110008190_,0,-0.009866378,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,propranolol,DB00571
,114400,DB06228,10013700,93,15819,28,16048,1.28329360763354e-09,3.369703597,2.186484054,5.344859312,3.4936688220246e-08,DB0622810013700_,17.16972832,1.214824787,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,rivaroxaban,DB06228
,114404,DB00820,10037884,56,11859,20,5796,0.270533177,1.368482021,0.807564307,2.410067408,0.433220324,DB0082010037884_,0.83650885,0.313702112,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,tadalafil,DB00820
,114410,DB06403,10054236,70,21401,15,6646,0.203852956,1.449175193,0.820898214,2.727845938,0.353623946,DB0640310054236_,1.039521229,0.370994562,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,114419,DB01101,10061623,46,7543,14,3894,0.100177105,1.6961468,0.914822812,3.344984929,0.211040731,DB0110110061623_,1.555704126,0.52835909,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,114441,DB00169,10070608,196,38495,165,18010,4.57029702388678e-08,0.55578866,0.449134319,0.688407097,8.88866128545054e-07,DB0016910070608_,13.9333192,-0.587367166,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,114443,DB00316,10070608,51,65423,45,36908,0.033012429,0.639336466,0.419670585,0.976982517,0.091309174,DB0031610070608_,2.393504016,-0.447324412,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,114444,DB00338,10070608,134,33540,116,22156,0.03805415,0.76310392,0.590330829,0.987635039,0.101718953,DB0033810070608_,2.285541627,-0.270361058,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,omeprazole,DB00338
,114445,DB00355,10070608,304,1489,181,1082,0.05602825,1.220391474,0.994996246,1.49978732,0.136153335,DB0035510070608_,1.993973567,0.199171688,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,aztreonam,DB00355
,114449,DB00904,10070608,60,23009,38,14418,1,0.989404765,0.647897932,1.527782767,1,DB0090410070608_,0,-0.010651764,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,114450,DB01222,10070608,90,9184,64,5341,0.239654397,0.817833131,0.585904264,1.147227979,0.397489634,DB0122210070608_,0.922586422,-0.20109696,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,budesonide,DB01222
,114452,DB06724,10070608,34,7895,18,3901,0.882679179,0.933325984,0.511765253,1.757703424,0.951006178,DB0672410070608_,0.05023472,-0.069000746,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,114453,DB08820,10070608,1000,3401,723,2822,0.012706432,1.147636132,1.028838856,1.280478977,0.043086958,DB0882010070608_,3.144534917,0.13770429,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,ivacaftor,DB08820
,114454,DB11065,10070608,444,2742,363,2325,0.648132581,1.037129165,0.890906667,1.207850835,0.783168329,DB1106510070608_,0.244407627,0.036456478,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,pancrelipase amylase,DB11065
,114468,DB00230,10039897,79,19595,47,8604,0.100163289,0.738040901,0.507519604,1.083771395,0.211020082,DB0023010039897_,1.555801977,-0.303756035,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,114474,DB00213,10040844,64,18831,46,13375,1,0.988192809,0.665601879,1.477331753,1,DB0021310040844_,0,-0.01187745,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,114476,DB08895,10040844,55,28059,21,6625,0.077817581,0.618393123,0.367649741,1.07737774,0.174666762,DB0889510040844_,1.744875335,-0.480630903,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,114506,DB01115,10037087,74,3526,34,2234,0.134872834,1.378893543,0.903486879,2.142720845,0.26246631,DB0111510037087_,1.337632548,0.321281397,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,nifedipine,DB01115
,114511,DB05676,10002034,55,47074,28,25301,0.908416409,1.055753056,0.658056487,1.729049977,0.959026229,DB0567610002034_,0.041836854,0.05425431,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,apremilast,DB05676
,114525,DB00043,10013573,198,6215,57,2243,0.149262166,1.25361016,0.92536384,1.72109099,0.282960856,DB0004310013573_,1.262446708,0.226027516,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,omalizumab,DB00043
,114526,DB00043,10020772,55,6358,15,2285,0.414293137,1.317702696,0.732212501,2.51645297,0.583584947,DB0004310020772_,0.538565255,0.275889838,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,omalizumab,DB00043
,114528,DB00043,10028813,167,6246,41,2259,0.025836954,1.47303037,1.037442284,2.134343329,0.075332704,DB0004310028813_,2.585840923,0.387321755,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,omalizumab,DB00043
,114530,DB00043,10037844,236,6177,88,2212,0.748308226,0.96036851,0.744873555,1.247311387,0.857074656,DB0004310037844_,0.154230251,-0.040438203,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,omalizumab,DB00043
,114533,DB00043,10047700,90,6323,23,2277,0.162495836,1.409051699,0.880806952,2.340880199,0.300651324,DB0004310047700_,1.201804077,0.342916924,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,omalizumab,DB00043
,114548,DB00996,10000125,35,38918,23,22402,0.682652495,0.875950398,0.503023227,1.553102662,0.808084703,DB0099610000125_,0.213088395,-0.132445813,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,114567,DB00222,10003239,76,3130,47,3081,0.013729127,1.591582788,1.087979086,2.349350668,0.045824774,DB0022210003239_,3.08293041,0.464728985,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,glimepiride,DB00222
,114568,DB00542,10003239,44,1642,22,1402,0.045418727,1.707385923,0.995961421,3.006979243,0.116363492,DB0054210003239_,2.151036436,0.534963501,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,benazepril,DB00542
,114594,DB09020,10012378,39,1915,17,1587,0.029745971,1.900831483,1.04570288,3.598184237,0.084158317,DB0902010012378_,2.475055532,0.642291413,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,bisacodyl,DB09020
,114604,DB09020,10012735,92,1862,53,1551,0.040553969,1.445769491,1.012771341,2.081781269,0.106745552,DB0902010012735_,2.237307294,0.368641699,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,bisacodyl,DB09020
,114606,DB00542,10013573,55,1631,42,1382,0.679101568,1.109540335,0.724049903,1.711053538,0.805768281,DB0054210013573_,0.215959071,0.103945817,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,benazepril,DB00542
,114610,DB00996,10015958,82,38871,30,22395,0.038624876,1.574761443,1.024746981,2.479887158,0.102873124,DB0099610015958_,2.274258852,0.454103796,NA,10015958,Eye pain,10015919,Eye disorders,Eye,gabapentin,DB00996
,114624,DB00542,10017955,34,1652,26,1398,0.793867629,1.106565921,0.641168622,1.930427242,0.888291402,DB0054210017955_,0.118455435,0.101261454,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,benazepril,DB00542
,114629,DB00999,10018627,44,21386,57,12182,4.3654056685374e-05,0.439716726,0.289596264,0.663681079,0.000394007,DB0099910018627_,7.839141159,-0.821624564,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,114642,DB00996,10021114,61,38892,23,22402,0.089095943,1.527655969,0.931546081,2.587129171,0.193800634,DB0099610021114_,1.640925308,0.423734514,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,gabapentin,DB00996
,114643,DB00999,10021114,40,21390,22,12217,1,1.038464136,0.602203932,1.835461957,1,DB0099910021114_,0,0.037742829,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,hydrochlorothiazide,DB00999
,114655,DB01039,10022086,32,2941,19,3032,0.06678643,1.736154576,0.952146505,3.24974994,0.15554504,DB0103910022086_,1.860819945,0.551672653,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,114676,DB00996,10027417,85,38868,48,22377,1,1.019500567,0.707158898,1.484853482,1,DB0099610027417_,0,0.019312867,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,114684,DB09020,10028813,143,1811,68,1536,0.00010918,1.783324735,1.315679207,2.436567595,0.000859868,DB0902010028813_,7.058731674,0.578479451,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,bisacodyl,DB09020
,114687,DB01039,10029331,40,2933,30,3021,0.229025796,1.373259696,0.831659023,2.289748229,0.384734648,DB0103910029331_,0.955201407,0.317187254,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,fenofibrate,DB01039
,114695,DB00222,10033425,89,3117,46,3082,0.00033408,1.91285609,1.320429861,2.803496121,0.002205802,DB0022210033425_,6.116664136,0.64859746,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,glimepiride,DB00222
,114724,DB00999,10038063,55,21375,39,12200,0.333844423,0.804936035,0.524043066,1.246948648,0.502914329,DB0099910038063_,0.687335443,-0.216992464,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,114746,DB00222,10044565,38,3168,32,3096,0.550334981,1.160483215,0.703965794,1.924129072,0.704616791,DB0022210044565_,0.350101182,0.148836483,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,glimepiride,DB00222
,114752,DB00996,10047461,110,38843,54,22371,0.371975786,1.173226369,0.839270266,1.65716783,0.541668294,DB0099610047461_,0.613101469,0.159757534,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,114753,DB00999,10047461,58,21372,22,12217,0.104341275,1.507022166,0.907813823,2.587266402,0.21752938,DB0099910047461_,1.525421359,0.410135629,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,114760,DB00996,10047531,45,38908,20,22405,0.368905526,1.295656869,0.749313065,2.316916246,0.538525033,DB0099610047531_,0.618921296,0.259017801,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,gabapentin,DB00996
,114765,DB09020,10047895,43,1911,38,1566,0.736377129,0.927315187,0.582115306,1.482373115,0.847745865,DB0902010047895_,0.165174375,-0.075461764,NA,10047895,Weight decreased,10022891,Investigations,Inv,bisacodyl,DB09020
,114767,DB00542,10048959,35,1651,20,1404,0.173363724,1.487999874,0.83121038,2.733549607,0.315354013,DB0054210048959_,1.154059419,0.397432851,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,benazepril,DB00542
,114769,DB09020,10048959,34,1920,23,1581,0.504423564,1.21718809,0.693127177,2.173889304,0.665450746,DB0902010048959_,0.407290655,0.196543354,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,bisacodyl,DB09020
,114833,DB01039,10061428,56,2917,38,3013,0.048421814,1.522068832,0.987011933,2.370090534,0.122129,DB0103910061428_,2.102677416,0.420070483,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,fenofibrate,DB01039
,114834,DB09020,10061428,48,1906,40,1564,1,0.984681344,0.630066981,1.546112108,1,DB0902010061428_,0,-0.015437199,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,bisacodyl,DB09020
,114864,DB00993,10003549,61,3188,37,1582,0.332141203,0.818169303,0.532502122,1.27219781,0.50100065,DB0099310003549_,0.691147881,-0.200685992,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,azathioprine,DB00993
,114871,DB00421,10044565,81,8822,39,5213,0.342652381,1.227214949,0.826295039,1.850330091,0.511957814,DB0042110044565_,0.669513052,0.204747333,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,114872,DB00421,10047571,61,8842,11,5241,6.82831839225635e-05,3.286777048,1.712101046,6.935419595,0.000574527,DB0042110047571_,7.461962828,1.189907464,female,10047571,Visual impairment,10015919,Eye disorders,Eye,spironolactone,DB00421
,114877,DB00169,10002424,43,38648,32,18143,0.062112762,0.630811365,0.389825055,1.030422355,0.147389541,DB0016910002424_,1.914676262,-0.460748406,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,114878,DB00927,10002424,30,7467,21,4995,0.886865645,0.95566353,0.528526501,1.758264571,0.95298528,DB0092710002424_,0.048155821,-0.045349384,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,famotidine,DB00927
,114880,DB00989,10016256,42,792,35,843,0.350778801,1.27708557,0.786991277,2.083479178,0.520517051,DB0098910016256_,0.652932632,0.244580583,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,rivastigmine,DB00989
,114896,DB01373,10015090,116,22604,39,7342,0.851650784,0.966099882,0.666170844,1.428125788,0.927152803,DB0137310015090_,0.075636891,-0.034488053,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,114898,DB00877,10016256,45,1063,44,1387,0.192451888,1.334285116,0.853746779,2.086697634,0.339719813,DB0087710016256_,1.079634079,0.288395655,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sirolimus,DB00877
,114899,DB10708,10016256,79,941,38,417,0.67783472,0.921330571,0.60661995,1.419475095,0.804755555,DB1070810016256_,0.217216706,-0.081936381,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,flax seed,DB10708
,114900,DB00877,10019211,39,1069,35,1396,0.122280195,1.454898728,0.8912595,2.383069204,0.244709347,DB0087710019211_,1.407684113,0.374936295,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sirolimus,DB00877
,114901,DB00338,10022000,407,33267,217,22055,0.009576587,1.243432546,1.050995334,1.474317682,0.034402159,DB0033810022000_,3.369635963,0.217875738,NA,10022000,Influenza,10021881,Infections and infestations,Infec,omeprazole,DB00338
,114902,DB00641,10022000,144,13980,96,12379,0.032085119,1.328202286,1.017599039,1.739975523,0.08929141,DB0064110022000_,2.415849991,0.283826363,NA,10022000,Influenza,10021881,Infections and infestations,Infec,simvastatin,DB00641
,114903,DB00715,10022000,40,4803,16,2271,0.667027431,1.182032487,0.645726248,2.266130542,0.797649652,DB0071510022000_,0.226085811,0.167235404,NA,10022000,Influenza,10021881,Infections and infestations,Infec,paroxetine,DB00715
,114905,DB00787,10022000,270,16730,277,16971,0.897215413,0.988769847,0.831893499,1.175122819,0.956338178,DB0078710022000_,0.044643686,-0.011293688,NA,10022000,Influenza,10021881,Infections and infestations,Infec,acyclovir,DB00787
,114906,DB00864,10022000,46,6823,57,8335,1,0.98585539,0.652728798,1.481957372,1,DB0086410022000_,0,-0.014245599,NA,10022000,Influenza,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,114908,DB08877,10022000,29,3260,32,3197,0.700310476,0.888753141,0.517406563,1.520737795,0.819879108,DB0887710022000_,0.198598379,-0.117935764,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ruxolitinib,DB08877
,114910,DB14513,10022000,95,7082,51,3513,0.658658056,0.924016457,0.649104893,1.328610914,0.791554443,DB1451310022000_,0.233756618,-0.079025397,NA,10022000,Influenza,10021881,Infections and infestations,Infec,magnesium,DB14513
,114911,DB00877,10028813,50,1058,37,1394,0.011004521,1.780068495,1.131321455,2.823206525,0.038418626,DB0087710028813_,3.25921289,0.576651844,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sirolimus,DB00877
,114913,DB00787,10047943,43,16957,25,17223,0.028451036,1.746941691,1.042651914,2.986251321,0.081268798,DB0078710047943_,2.509993124,0.557866654,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,acyclovir,DB00787
,114915,DB01373,10047943,67,22653,21,7360,1,1.036609312,0.626371872,1.783599557,1,DB0137310047943_,0,0.03595511,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,calcium,DB01373
,114922,DB14513,10050584,72,7105,22,3542,0.04731402,1.631459108,0.998197848,2.767573474,0.120049136,DB1451310050584_,2.119854156,0.489474773,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium,DB14513
,114950,DB14513,10061623,75,7102,44,3520,0.379424303,0.844857211,0.573320998,1.258137676,0.549425287,DB1451310061623_,0.59888248,-0.168587647,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,114954,DB14513,10061818,50,7127,41,3523,0.018636019,0.602841469,0.39008463,0.936405727,0.058447412,DB1451310061818_,2.839627864,-0.50610102,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,114957,DB00313,10011906,60,1179,73,1444,1,1.006655754,0.696851295,1.449591672,1,DB0031310011906_,0,0.006633702,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,valproic acid,DB00313
,114988,DB00514,10028813,79,2087,31,1505,0.004218647,1.83742826,1.191663512,2.896617272,0.017834681,DB0051410028813_,4.026610344,0.608366909,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dextromethorphan,DB00514
,114989,DB00535,10028813,52,1152,18,628,0.12441961,1.57448611,0.896697781,2.885976584,0.247698966,DB0053510028813_,1.395541116,0.453928939,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cefdinir,DB00535
,114990,DB13867,10028813,330,4220,109,2445,3.30494080125143e-07,1.753967303,1.399810549,2.211203412,5.32783618282084e-06,DB1386710028813_,12.14256537,0.561880252,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fluticasone,DB13867
,114992,DB00514,10033371,48,2118,13,1523,0.000981567,2.654401114,1.409450958,5.359447505,0.005421408,DB0051410033371_,5.217399763,0.97621906,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,dextromethorphan,DB00514
,114993,DB01241,10033371,43,900,29,1042,0.029996625,1.716224064,1.03744396,2.876063236,0.084698976,DB0124110033371_,2.468651771,0.540126566,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,gemfibrozil,DB01241
,114995,DB00535,10037660,36,1168,19,627,1,1.017114398,0.562721858,1.893898011,1,DB0053510037660_,0,0.016969596,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,cefdinir,DB00535
,114997,DB11133,10037660,48,2383,35,1539,0.649886145,0.885731826,0.558200485,1.417931274,0.784615544,DB1113310037660_,0.242561434,-0.121341053,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,114999,DB00281,10040753,592,10866,150,5521,2.55117629874852e-15,2.0052224,1.668397178,2.422102423,1.63356075548367e-13,DB0028110040753_,29.44284406,0.695754977,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,lidocaine,DB00281
,115000,DB00425,10040753,195,12500,43,7441,1.89260707865757e-10,2.699396829,1.929194457,3.853625907,5.90470944362185e-09,DB0042510040753_,18.94751559,0.993028351,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,zolpidem,DB00425
,115002,DB00535,10040753,73,1131,24,622,0.03707088,1.672352394,1.029592783,2.803850881,0.0997316,DB0053510040753_,2.305272705,0.514231254,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,cefdinir,DB00535
,115003,DB00722,10040753,275,25128,131,25901,8.79365551557961e-14,2.163770608,1.749679931,2.687038589,4.55002431549232e-12,DB0072210040753_,26.11588854,0.771852352,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,lisinopril,DB00722
,115004,DB00904,10040753,260,22809,79,14377,2.90701759860571e-09,2.074432818,1.60532976,2.705911461,7.36491157391335e-08,DB0090410040753_,16.4239537,0.729687775,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,115005,DB01060,10040753,346,8241,104,4977,1.14989815376808e-10,2.009136219,1.604424117,2.533548532,3.71315392773881e-09,DB0106010040753_,19.41138421,0.697704888,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,115014,DB08882,10028813,66,931,44,949,0.03900848,1.528667118,1.016422711,2.318197241,0.103674206,DB0888210028813_,2.266501927,0.424396191,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,linagliptin,DB08882
,115015,DB09072,10017577,61,6410,23,2512,1,1.039318257,0.632347186,1.763763107,1,DB0907210017577_,0,0.038564976,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,115023,DB08868,10019974,188,9014,39,2472,0.120989582,1.321940078,0.929243859,1.923189895,0.242856904,DB0886810019974_,1.41528288,0.279100414,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,fingolimod,DB08868
,115027,DB08868,10049438,41,9161,18,2493,0.109789941,0.619885183,0.347539864,1.14842628,0.225755191,DB0886810049438_,1.488304093,-0.478221006,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,115031,DB00108,10002198,46,10148,10,3285,0.279331947,1.488989223,0.740142952,3.312838062,0.443150221,DB0010810002198_,0.813846467,0.398097516,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,natalizumab,DB00108
,115051,DB00108,10042772,42,10152,17,3278,0.447915203,0.797744707,0.443808909,1.49686746,0.615701868,DB0010810042772_,0.484992413,-0.225966649,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,115052,DB00108,10046543,39,10155,16,3279,0.432165025,0.787071768,0.429140958,1.510757877,0.600631189,DB0010810046543_,0.509774196,-0.239435843,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,natalizumab,DB00108
,115054,DB00047,10020100,31,9254,19,8499,0.20171287,1.49842564,0.819447114,2.809587074,0.3511152,DB0004710020100_,1.046640903,0.404414984,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,115060,DB06589,10020772,90,1940,88,2565,0.053693497,1.352110138,0.990383408,1.846454998,0.131900334,DB0658910020772_,2.025708685,0.301666438,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,pazopanib,DB06589
,115062,DB01306,10042674,39,4169,23,3843,0.097448945,1.562967828,0.908632913,2.746624474,0.207050655,DB0130610042674_,1.574791806,0.446586468,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,115089,DB06643,10020583,56,52365,13,7502,0.141671644,0.617144997,0.333113342,1.230772306,0.272105403,DB0664310020583_,1.301565776,-0.48265128,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,denosumab,DB06643
,115117,DB00950,10003553,90,4628,21,2035,0.008896282,1.884338395,1.157920613,3.200893301,0.032416827,DB0095010003553_,3.429077636,0.633576775,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fexofenadine,DB00950
,115121,DB00586,10013781,58,7051,11,2794,0.022137597,2.089219524,1.083683766,4.42126659,0.066943791,DB0058610013781_,2.703901957,0.736790563,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,diclofenac,DB00586
,115125,DB00927,10013781,42,7455,19,4997,0.189941834,1.481644743,0.841806116,2.700696046,0.336423308,DB0092710013781_,1.089385065,0.393152783,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,115130,DB00341,10013786,61,11344,32,5036,0.432654946,0.846274905,0.542265748,1.343563593,0.601074802,DB0034110013786_,0.509035889,-0.166911026,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,cetirizine,DB00341
,115136,DB00950,10013786,42,4676,11,2045,0.136144307,1.66972913,0.842723694,3.603577123,0.264304671,DB0095010013786_,1.330652783,0.512661416,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,fexofenadine,DB00950
,115140,DB00586,10013946,69,7040,13,2792,0.013163575,2.104850913,1.151237701,4.157343659,0.044333982,DB0058610013946_,3.11600381,0.74424464,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,diclofenac,DB00586
,115144,DB00927,10013946,74,7423,35,4981,0.095326503,1.418694265,0.9351693,2.189493151,0.203745091,DB0092710013946_,1.590885619,0.349736917,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,115145,DB00950,10013946,44,4674,14,2042,0.389221771,1.37305914,0.736485578,2.719219065,0.559115436,DB0095010013946_,0.581399322,0.317041199,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,fexofenadine,DB00950
,115194,DB00996,10043882,96,38857,48,22377,0.437280585,1.151783881,0.805974104,1.665177277,0.605708272,DB0099610043882_,0.501356808,0.141311941,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,gabapentin,DB00996
,115197,DB00091,10052140,66,5444,13,2657,0.001575163,2.477617139,1.350919467,4.905493956,0.008001334,DB0009110052140_,4.828147055,0.907297267,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,cyclosporine,DB00091
,115232,DB01050,10033775,230,17878,88,9283,0.014685035,1.357098223,1.055576646,1.75774407,0.048479798,DB0105010033775_,3.026608099,0.305348761,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,115234,DB00108,10038695,35,10159,16,3279,0.254002136,0.706075004,0.380047357,1.368125673,0.414585554,DB0010810038695_,0.880475922,-0.348033809,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,natalizumab,DB00108
,115258,DB00175,10035528,72,8059,75,6031,0.053678151,0.718448181,0.511681736,1.008120504,0.13188736,DB0017510035528_,2.025807054,-0.330661697,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,pravastatin,DB00175
,115259,DB00471,10035528,87,14102,44,5421,0.142644884,0.760095728,0.522312564,1.120166755,0.273516367,DB0047110035528_,1.296393815,-0.274310895,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,montelukast,DB00471
,115261,DB00471,10038153,39,14150,26,5439,0.036528466,0.57659864,0.341848697,0.987518166,0.098628735,DB0047110038153_,2.316392628,-0.550608853,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,montelukast,DB00471
,115263,DB01136,10038153,46,9838,45,11070,0.5288472,1.150224704,0.745125456,1.776583646,0.686168703,DB0113610038153_,0.376631759,0.139957318,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,carvedilol,DB01136
,115265,DB00813,10050584,52,10520,20,10148,0.000331275,2.508143805,1.470582156,4.438298988,0.00218948,DB0081310050584_,6.124091217,0.91954296,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,115267,DB00213,10054112,243,18652,164,13257,0.648774402,1.053136921,0.859211252,1.29343228,0.783705286,DB0021310054112_,0.243722241,0.051773254,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,pantoprazole,DB00213
,115268,DB00215,10054112,86,11017,28,5248,0.087214277,1.463057878,0.943969799,2.331385991,0.190458622,DB0021510054112_,1.658320314,0.380528682,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,citalopram,DB00215
,115269,DB00471,10054112,188,14001,87,5378,0.154992526,0.830077028,0.639096897,1.08510953,0.29078746,DB0047110054112_,1.235162655,-0.186236778,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,montelukast,DB00471
,115270,DB00497,10054112,170,19097,125,16250,0.218700307,1.157244629,0.912323721,1.471238068,0.37195384,DB0049710054112_,0.988985518,0.14604186,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,oxycodone,DB00497
,115271,DB00656,10054112,103,11910,85,6534,0.007173565,0.66477872,0.493157204,0.89820609,0.027307335,DB0065610054112_,3.600599921,-0.408301046,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,trazodone,DB00656
,115272,DB00727,10054112,34,3809,45,4128,0.42869883,0.818853868,0.507482288,1.31028908,0.597220095,DB0072710054112_,0.515469565,-0.199849638,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,nitroglycerin,DB00727
,115273,DB00813,10054112,82,10490,61,10107,0.131419879,1.295162824,0.917416326,1.836942883,0.257782325,DB0081310054112_,1.355639752,0.25863642,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,fentanyl,DB00813
,115275,DB00497,10064355,42,19225,41,16334,0.581785631,0.870350029,0.552045019,1.373106207,0.730061601,DB0049710064355_,0.314626364,-0.138859816,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,115279,DB01041,10017955,32,3013,45,3073,0.170703273,0.725312159,0.444785845,1.17044568,0.311807027,DB0104110017955_,1.165370785,-0.321153152,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,thalidomide,DB01041
,115280,DB01041,10037660,28,3017,60,3058,0.001152691,0.473065873,0.28993852,0.75502607,0.006196641,DB0104110037660_,5.083747858,-0.748520633,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,thalidomide,DB01041
,115306,DB00788,10020642,87,9269,34,5027,0.125513173,1.387736304,0.922109256,2.131450878,0.249394394,DB0078810020642_,1.388719723,0.327673862,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,naproxen,DB00788
,115325,DB00480,10061599,111,67317,66,67596,0.00068168,1.688771544,1.233967356,2.326678332,0.00400348,DB0048010061599_,5.520591175,0.524001367,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,115333,DB13867,10028810,89,4461,33,2521,0.045206089,1.524026316,1.008248514,2.353934052,0.115982629,DB1386710028810_,2.154314845,0.421355725,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,fluticasone,DB13867
,115334,DB13867,10039101,44,4506,12,2542,0.024725379,2.068312999,1.071371442,4.3101736,0.072888083,DB1386710039101_,2.618830121,0.726733298,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,115335,DB00333,10003988,52,3019,35,3117,0.052377216,1.533827672,0.97716547,2.433691143,0.129477582,DB0033310003988_,2.044247525,0.427766358,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,methadone,DB00333
,115337,DB00624,10003988,7,555,61,4335,1,0.89632553,0.344122371,1.974120807,1,DB0062410003988_,0,-0.109451617,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,testosterone,DB00624
,115343,DB00959,10024855,44,8034,24,4978,0.707773121,1.135979588,0.674868379,1.955677897,0.825368965,DB0095910024855_,0.191924762,0.127495351,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,115350,DB00959,10047899,115,7963,38,4964,0.000558583,1.886467133,1.294558483,2.803986547,0.003383032,DB0095910047899_,5.688982789,0.634705838,NA,10047899,Weight increased,10022891,Investigations,Inv,methylprednisolone,DB00959
,115353,DB05676,10028596,61,47068,61,25268,0.00080335,0.536824884,0.370081438,0.778718787,0.004590947,DB0567610028596_,5.383668872,-0.622083338,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,apremilast,DB05676
,115354,DB05679,10028596,21,6910,42,4867,8.67123154815535e-05,0.352201113,0.197875657,0.609179414,0.00070641,DB0567910028596_,7.255314161,-1.043552923,male,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,ustekinumab,DB05679
,115355,DB01015,10038695,128,9759,179,9202,0.000816619,0.674288394,0.532159045,0.852370213,0.004657659,DB0101510038695_,5.369242338,-0.394097375,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,115361,DB00065,10009887,43,9421,46,4911,0.001037386,0.487299756,0.313482476,0.756275687,0.005681362,DB0006510009887_,5.170564199,-0.718875829,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,infliximab,DB00065
,115363,DB00404,10009887,48,19844,21,9841,0.701840778,1.133515404,0.665387621,1.994170936,0.8210372,DB0040410009887_,0.19718686,0.125323781,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,115364,DB00433,10009887,71,7585,36,5984,0.031458088,1.555885034,1.026222505,2.396040148,0.08791875,DB0043310009887_,2.431342185,0.442044538,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,115365,DB00497,10009887,81,19186,48,16327,0.051299838,1.436019844,0.992083635,2.098558715,0.127452547,DB0049710009887_,2.060011161,0.361875289,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,115368,DB00741,10009887,32,4062,29,3145,0.604538217,0.854364849,0.49939289,1.467205797,0.747842343,DB0074110009887_,0.290563095,-0.157396953,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,hydrocortisone,DB00741
,115369,DB00916,10009887,75,5248,46,2385,0.114671545,0.740975168,0.504872874,1.097791899,0.233142109,DB0091610009887_,1.456107101,-0.299788166,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,metronidazole,DB00916
,115370,DB00065,10011906,31,9433,30,4927,0.020776192,0.539728491,0.315660124,0.924165708,0.06368539,DB0006510011906_,2.753800102,-0.616689059,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,115371,DB00557,10011906,201,5786,170,2897,1.29267301468861e-06,0.592011706,0.477824394,0.734173769,1.79824875316698e-05,DB0055710011906_,10.92611219,-0.524228871,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,115372,DB00620,10011906,86,4742,117,3015,1.1854549882251e-07,0.4673857,0.348265897,0.625222697,2.12042765331723e-06,DB0062010011906_,13.06389277,-0.760600452,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,115374,DB00433,10046735,53,7603,30,5990,0.151281501,1.391828136,0.871960405,2.259375382,0.285642861,DB0043310046735_,1.253012988,0.330618089,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,prochlorperazine,DB00433
,115375,DB00620,10046735,73,4755,40,3092,0.438067886,1.186672006,0.794003712,1.796361188,0.606476097,DB0062010046735_,0.500089962,0.171152756,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,triamcinolone,DB00620
,115378,DB01225,10001053,52,4992,41,4599,0.467581961,1.168425613,0.759407942,1.808383416,0.634130065,DB0122510001053_,0.455501196,0.155657212,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enoxaparin,DB01225
,115380,DB11089,10001053,78,10097,55,8352,0.383024629,1.173075993,0.819062053,1.690150263,0.55309998,DB1108910001053_,0.592216498,0.159629353,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,115382,DB00722,10024670,31,25372,34,25998,0.805131139,0.934235078,0.555093767,1.567137064,0.894533435,DB0072210024670_,0.111452999,-0.068027183,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,lisinopril,DB00722
,115388,DB00281,10008190,71,11387,52,5619,0.034192027,0.673758381,0.463823539,0.984406046,0.09379924,DB0028110008190_,2.366598529,-0.394883718,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,115391,DB00874,10008190,34,3301,26,1950,0.347974544,0.77254695,0.44853327,1.345006575,0.517570784,DB0087410008190_,0.658608983,-0.258062496,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,guaifenesin,DB00874
,115392,DB01109,10008190,55,4357,42,4228,0.2620819,1.270714402,0.832969337,1.950966064,0.423797154,DB0110910008190_,0.858500348,0.239579264,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,heparin,DB01109
,115399,DB00627,10016825,36,1293,23,1576,0.017104792,1.907350754,1.093468333,3.389865273,0.054649261,DB0062710016825_,2.906819591,0.64571524,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,niacin,DB00627
,115405,DB00374,10013911,58,17658,19,5705,1,0.986253634,0.578252722,1.755217296,1,DB0037410013911_,0,-0.013841722,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,115406,DB06403,10013911,40,21431,13,6648,0.871965603,0.954474194,0.499709705,1.946211878,0.943737786,DB0640310013911_,0.057906921,-0.046594673,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,115407,DB00108,10022000,91,10103,24,3271,0.445313131,1.227585797,0.774322979,2.016972876,0.613309841,DB0010810022000_,0.48888502,0.205049474,NA,10022000,Influenza,10021881,Infections and infestations,Infec,natalizumab,DB00108
,115435,DB00697,10048010,54,6042,16,1790,1,0.99987793,0.562069376,1.876510796,1,DB0069710048010_,0,-0.000122078,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,115439,DB00374,10054996,39,17677,13,5711,0.872845161,0.969225075,0.506036025,1.980314327,0.944495289,DB0037410054996_,0.05710458,-0.031258419,NA,10054996,Infusion site reaction,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,115450,DB01065,10002855,109,4222,40,3011,0.000275142,1.943212334,1.336634172,2.875235549,0.001880913,DB0106510002855_,6.275997842,0.664342446,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,melatonin,DB01065
,115452,DB01065,10003239,100,4231,32,3019,5.06302734147521e-05,2.229582578,1.479527023,3.441424009,0.000446808,DB0106510003239_,7.713382256,0.801814383,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,melatonin,DB01065
,115454,DB11093,10003239,72,1585,15,645,0.020734736,1.952827363,1.099008474,3.696481779,0.063584266,DB1109310003239_,2.755389223,0.669278252,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium citrate,DB11093
,115461,DB01065,10010774,122,4209,70,2981,0.181367302,1.234333463,0.908943565,1.687148754,0.325586636,DB0106510010774_,1.12212669,0.210531118,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,melatonin,DB01065
,115463,DB14513,10010774,219,6958,85,3479,0.055249982,1.288243525,0.99482585,1.680716134,0.134772936,DB1451310010774_,2.004163872,0.253279682,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,115464,DB00169,10013710,109,38582,99,18076,3.13731931803343e-06,0.515818938,0.389090635,0.684569838,3.93718970038237e-05,DB0016910013710_,10.14245827,-0.661999471,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,115465,DB01065,10013710,58,4273,49,3002,0.37378137,0.831616515,0.55696675,1.24610521,0.543586774,DB0106510013710_,0.609565927,-0.184383864,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,115467,DB13961,10013710,39,9418,33,6381,0.399611184,0.800738932,0.490160891,1.31532868,0.569495769,DB1396110013710_,0.563003925,-0.222220313,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,115468,DB14513,10013710,30,7147,20,3544,0.29658565,0.743800693,0.40801943,1.384069779,0.462422743,DB1451310013710_,0.771275778,-0.295982166,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,115476,DB14513,10013781,69,7108,12,3552,0.000313419,2.873153519,1.541471789,5.836106568,0.002092243,DB1451310013781_,6.169518719,1.055410214,female,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,115480,DB13961,10013786,59,9398,30,6384,0.233319608,1.335919477,0.845847779,2.150524135,0.389904373,DB1396110013786_,0.941853767,0.289619801,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,fish oil,DB13961
,115481,DB14513,10013786,48,7129,16,3548,0.184013915,1.493004742,0.831630014,2.820860655,0.328967269,DB1451310013786_,1.111797019,0.400790695,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,magnesium,DB14513
,115484,DB14513,10022437,151,7026,57,3507,0.07474061,1.322294861,0.966002202,1.831358074,0.169426243,DB1451310022437_,1.775337591,0.279368758,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,magnesium,DB14513
,115485,DB00047,10001760,73,9212,17,8501,1.4938644137162e-08,3.962250707,2.311537163,7.173416635,3.22118343843562e-07,DB0004710001760_,14.94834683,1.376812224,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,insulin glargine,DB00047
,115492,DB14513,10047899,165,7012,55,3509,0.009098889,1.501230593,1.096918925,2.081783947,0.033015502,DB1451310047899_,3.410778081,0.406285167,NA,10047899,Weight increased,10022891,Investigations,Inv,magnesium,DB14513
,115493,DB01240,10009033,44,5707,9,1567,0.504046854,1.342309185,0.644922881,3.134334836,0.665170778,DB0124010009033_,0.407711463,0.294391403,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,115542,DB00588,10036653,33,16491,23,8445,0.260396682,0.734727632,0.41828791,1.311436399,0.421824651,DB0058810036653_,0.863165571,-0.308255417,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,115543,DB01076,10036653,51,25696,61,25522,0.345098372,0.830408398,0.56080478,1.225174168,0.514527096,DB0107610036653_,0.66450706,-0.185837653,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,115546,DB00588,10051792,38,16486,24,8444,0.422583551,0.810994005,0.473676107,1.414299313,0.591569709,DB0058810051792_,0.524975751,-0.209494617,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,115547,DB00904,10051792,123,22946,90,14366,0.25969052,0.85564907,0.646109889,1.136796262,0.420875255,DB0090410051792_,0.865418796,-0.155894951,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,115548,DB01076,10051792,47,25700,40,25543,0.520122763,1.167817374,0.749416437,1.827686869,0.679241179,DB0107610051792_,0.386779017,0.155136514,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,115552,DB08932,10053377,60,19383,6,6591,0.001556416,3.400416331,1.47308332,9.634566926,0.007924533,DB0893210053377_,4.837791947,1.223897874,female,10053377,Central venous catheterisation,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,115553,DB06228,10064687,37,15875,24,16052,0.096186157,1.558824987,0.907546676,2.725087588,0.205007349,DB0622810064687_,1.584709454,0.443932324,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,115554,DB00537,10008531,71,7486,37,4261,0.689012666,1.092243379,0.722669911,1.675221505,0.81249806,DB0053710008531_,0.207641753,0.088233727,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,115555,DB00559,10008531,76,9583,19,3287,0.238863235,1.37195761,0.819869988,2.406557974,0.396584034,DB0055910008531_,0.924867321,0.316238633,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,115556,DB06292,10017533,129,1228,48,1185,1.28514454489006e-08,2.592549254,1.828438526,3.727110329,2.81734982172104e-07,DB0629210017533_,15.08229899,0.95264166,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,dapagliflozin,DB06292
,115573,DB00181,10021015,42,9814,16,5855,0.135902781,1.566023824,0.861259196,2.986662053,0.263962506,DB0018110021015_,1.331948207,0.448539811,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,baclofen,DB00181
,115582,DB08911,10013573,28,1611,30,1718,1,0.995325045,0.570185655,1.732545072,1,DB0891110013573_,0,-0.004685917,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,trametinib,DB08911
,115586,DB00028,10042682,48,13410,19,5596,0.894091883,1.054229694,0.607586764,1.900922714,0.955860142,DB0002810042682_,0.045143671,0.052810352,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,115587,DB00959,10042682,44,8034,15,4987,0.044215855,1.820749073,0.992653295,3.526203872,0.114020773,DB0095910042682_,2.171374625,0.599247995,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,115588,DB00028,10042727,38,13420,14,5601,0.762285492,1.132829058,0.599437468,2.265357581,0.868285351,DB0002810042727_,0.141234873,0.124718095,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,human immunoglobulin g,DB00028
,115589,DB00028,10047513,43,13415,18,5597,1,0.996691259,0.5622624,1.837696698,1,DB0002810047513_,0,-0.003314227,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,human immunoglobulin g,DB00028
,115590,DB00959,10047513,63,8015,27,4975,0.127153386,1.44828659,0.907726111,2.368526239,0.251664225,DB0095910047513_,1.379659521,0.370381196,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,methylprednisolone,DB00959
,115591,DB01075,10047513,103,19845,48,11049,0.349205286,1.19468864,0.839581609,1.7212485,0.518740906,DB0107510047513_,0.656350739,0.1778856,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,diphenhydramine,DB01075
,115592,DB00230,10002544,86,19588,19,8632,0.005483444,1.994605725,1.202287687,3.474906705,0.022025109,DB0023010002544_,3.815572148,0.690446399,NA,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,115594,DB00476,10002544,42,17215,8,6169,0.108540196,1.881373679,0.871900271,4.642458123,0.223833286,DB0047610002544_,1.496853763,0.63200219,NA,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,115596,DB00973,10013709,151,3700,110,2911,0.567584818,1.080014354,0.834909343,1.400576012,0.718726578,DB0097310013709_,0.330274274,0.076974332,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,115601,DB01296,10053762,40,1409,15,968,0.051220504,1.831603254,0.983394476,3.590413747,0.127336701,DB0129610053762_,2.060920508,0.605191678,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,glucosamine,DB01296
,115606,DB00451,10037855,110,47161,22,15397,0.033566129,1.63232131,1.025570814,2.711425956,0.092497321,DB0045110037855_,2.380575595,0.490003118,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,115609,DB00243,10011906,59,1195,147,1479,5.56773324789386e-06,0.496861738,0.357374184,0.683517167,6.49280693970231e-05,DB0024310011906_,9.642230525,-0.699443484,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ranolazine,DB00243
,115635,DB01109,10035528,44,4368,63,4207,0.051257708,0.672704613,0.44588724,1.00701957,0.127379187,DB0110910035528_,2.06058692,-0.396448956,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,heparin,DB01109
,115662,DB00295,10005734,55,14608,25,9577,0.137421862,1.442297808,0.883053618,2.417269307,0.266126401,DB0029510005734_,1.323783893,0.366237542,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,morphine,DB00295
,115664,DB00476,10005734,50,17207,31,6146,0.022086029,0.576114934,0.360530231,0.933907905,0.066827589,DB0047610005734_,2.705639278,-0.5514481,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,duloxetine,DB00476
,115678,DB00451,10025082,99,47172,36,15383,0.550013469,0.896775872,0.606431644,1.35302217,0.704376082,DB0045110025082_,0.350442859,-0.108949312,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,115685,DB00476,10048294,63,17194,47,6130,0.000195982,0.477891624,0.321983645,0.713674487,0.001416579,DB0047610048294_,6.559510725,-0.738371299,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,115686,DB00295,10048334,34,14629,23,9579,0.89306524,0.967940281,0.553430413,1.722073148,0.955451035,DB0029510048334_,0.045571762,-0.032584887,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,115701,DB08895,10034839,46,28068,6,6640,0.215391575,1.813644441,0.772211902,5.199192358,0.367869232,DB0889510034839_,1.000027751,0.595338324,NA,10034839,Pharyngitis streptococcal,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,115703,DB13867,10037377,28,4522,31,2523,0.00939384,0.503983304,0.290562544,0.870607088,0.033859843,DB1386710037377_,3.385525539,-0.685212137,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,115713,DB00374,10033295,54,17662,18,5706,0.891121924,0.969198941,0.558990944,1.757435045,0.954799437,DB0037410033295_,0.046253975,-0.031285383,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,115719,DB00213,10074903,82,18813,26,13395,0.000178543,2.245493539,1.428313986,3.640093907,0.001309979,DB0021310074903_,6.637744113,0.808925336,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,115773,DB00264,10014011,45,29562,31,24861,0.42137232,1.220769556,0.755426429,1.996092157,0.590435306,DB0026410014011_,0.526895207,0.199481444,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,115775,DB00316,10014011,216,65258,88,36865,0.010006422,1.386596781,1.076946988,1.798066562,0.035581547,DB0031610014011_,3.335928116,0.326852386,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,115783,DB00761,10014011,42,15265,10,8615,0.013138832,2.370247632,1.169518068,5.300733427,0.044264831,DB0076110014011_,3.117564799,0.862994436,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,115785,DB00863,10014011,36,10637,23,5817,0.586287656,0.855977466,0.493005156,1.514531116,0.733522349,DB0086310014011_,0.309897212,-0.155511228,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,ranitidine,DB00863
,115786,DB00904,10014011,68,23001,35,14421,0.363147992,1.218078631,0.798347767,1.888390531,0.532664662,DB0090410014011_,0.629863205,0.197274725,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,ondansetron,DB00904
,115788,DB00996,10014011,81,38872,22,22403,0.00137094,2.121906589,1.310765502,3.57204456,0.007142038,DB0099610014011_,4.941757085,0.752315019,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,115789,DB01050,10014011,63,18045,34,9337,0.830866119,0.958779026,0.621610616,1.50200526,0.911471627,DB0105010014011_,0.092694813,-0.042094652,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,115790,DB01222,10014011,45,9229,22,5383,0.528390256,1.193076616,0.700737807,2.088667711,0.685783201,DB0122210014011_,0.377193734,0.176535362,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,budesonide,DB01222
,115794,DB00333,10035664,78,2993,47,3105,0.003688446,1.721515665,1.179195121,2.536913632,0.015983976,DB0033310035664_,4.136168549,0.543205104,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,methadone,DB00333
,115798,DB06273,10035664,91,5004,26,1384,0.909831325,0.968028126,0.617294396,1.56664626,0.959437782,DB0627310035664_,0.04140781,-0.032494137,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,tocilizumab,DB06273
,115799,DB00863,10037377,66,10607,45,5795,0.2733093,0.801320555,0.539566409,1.199549418,0.436262522,DB0086310037377_,0.829511103,-0.221494218,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,115802,DB00273,10040753,129,8352,16,2177,0.003538006,2.101366455,1.242648686,3.794698421,0.015451771,DB0027310040753_,4.170031627,0.742587826,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,topiramate,DB00273
,115806,DB00433,10040753,53,7603,25,5995,0.038921917,1.67156636,1.01923207,2.810677935,0.103470301,DB0043310040753_,2.268470655,0.513761127,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,115808,DB00761,10040753,228,15079,40,8585,1.43028974362831e-14,3.245071645,2.308278958,4.66735646,8.22651332850551e-13,DB0076110040753_,27.82624394,1.177137428,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,115809,DB00863,10040753,222,10451,54,5786,8.21877633041576e-09,2.275938365,1.680488672,3.129581509,1.88508320981656e-07,DB0086310040753_,15.48412369,0.822392436,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,ranitidine,DB00863
,115811,DB00996,10040753,422,38531,95,22330,1.86196309346122e-19,2.574308351,2.054766313,3.252976559,1.83646153514552e-17,DB0099610040753_,38.53610594,0.945580897,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,gabapentin,DB00996
,115814,DB06273,10040753,50,5045,6,1404,0.049594856,2.318961182,0.990933805,6.632824298,0.124253041,DB0627310040753_,2.085435137,0.841119319,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,tocilizumab,DB06273
,115829,DB00497,10009802,14,19253,55,16320,1.47586417682848e-08,0.215806735,0.110763929,0.393502053,3.18498274942008e-07,DB0049710009802_,14.95964878,-1.533372016,male,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,oxycodone,DB00497
,115834,DB00425,10012601,37,12658,29,7455,0.25286367,0.751455014,0.449282692,1.267928488,0.413186719,DB0042510012601_,0.883855684,-0.285743933,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,zolpidem,DB00425
,115835,DB00641,10012601,65,14059,47,12428,0.298728993,1.222527467,0.826441846,1.820495593,0.464720053,DB0064110012601_,0.766320092,0.20092041,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,simvastatin,DB00641
,115836,DB00682,10012601,39,19420,44,16320,0.186959005,0.744885515,0.471113255,1.173731971,0.332671097,DB0068210012601_,1.100600974,-0.294524744,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,115837,DB00758,10012601,40,8260,32,10042,0.096037052,1.519619673,0.929924044,2.501674047,0.204847352,DB0075810012601_,1.585490203,0.418460088,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,clopidogrel,DB00758
,115841,DB00863,10016322,178,10495,57,5783,0.000258668,1.720689966,1.267841837,2.365822028,0.001787586,DB0086310016322_,6.326889422,0.542725354,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,115844,DB00338,10018852,46,33628,38,22234,0.317050193,0.800381328,0.509304931,1.264486955,0.484839534,DB0033810018852_,0.723937301,-0.222667005,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,omeprazole,DB00338
,115851,DB00321,10021097,124,7323,46,2804,0.931154435,1.032193358,0.728085886,1.485503206,0.97224892,DB0032110021097_,0.028143416,0.031686012,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,amitriptyline,DB00321
,115854,DB00321,10028836,53,7394,10,2840,0.034369399,2.035596639,1.02306512,4.49412794,0.094150411,DB0032110028836_,2.362861661,0.710788965,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,amitriptyline,DB00321
,115855,DB00327,10028836,48,6090,16,4246,0.010261497,2.091478675,1.165110784,3.951346192,0.036309275,DB0032710028836_,3.315682061,0.737871316,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydromorphone,DB00327
,115856,DB00425,10028836,74,12621,32,7452,0.1581759,1.365382589,0.889548408,2.138948453,0.295015507,DB0042510028836_,1.220727359,0.311434675,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,115857,DB00678,10028836,75,15524,39,10685,0.180921604,1.323618462,0.886626991,2.003849619,0.325038734,DB0067810028836_,1.123810922,0.280369245,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,115861,DB01016,10033425,33,1068,26,1202,0.188398445,1.428248611,0.822462373,2.504170978,0.334530373,DB0101610033425_,1.095027601,0.356448946,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,glyburide,DB01016
,115865,DB00425,10038428,31,12664,20,7464,0.772626261,0.913555869,0.503975636,1.692386009,0.875573143,DB0042510038428_,0.132876586,-0.090410746,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,zolpidem,DB00425
,115866,DB00497,10038428,35,19232,37,16338,0.407567355,0.80360964,0.49124291,1.312241064,0.577004341,DB0049710038428_,0.549905489,-0.218641651,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,oxycodone,DB00497
,115867,DB00641,10038428,50,14074,44,12431,1,1.003704384,0.655384508,1.541937699,1,DB0064110038428_,0,0.003697539,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,simvastatin,DB00641
,115868,DB00678,10038428,70,15529,40,10684,0.38215999,1.203977992,0.80437226,1.824231718,0.552230639,DB0067810038428_,0.593789495,0.185631067,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,losartan,DB00678
,115882,DB00497,10040829,61,19206,31,16344,0.020812906,1.674488803,1.069156815,2.671271889,0.063768182,DB0049710040829_,2.752500929,0.515507927,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,115883,DB00678,10040829,82,15517,42,10682,0.142403765,1.344015834,0.914896995,2.000466908,0.273177855,DB0067810040829_,1.297632214,0.295662023,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,115884,DB00863,10040829,36,10637,24,5816,0.499097905,0.82017804,0.475484318,1.438536239,0.66097939,DB0086310040829_,0.41403262,-0.19823384,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,115890,DB00695,10040831,46,28003,35,20493,0.910513373,0.961792639,0.606003041,1.538644204,0.959635541,DB0069510040831_,0.041201712,-0.038956403,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,furosemide,DB00695
,115919,DB00321,10050584,56,7391,17,2833,0.434089928,1.262604721,0.721525249,2.322064858,0.602606552,DB0032110050584_,0.50649078,0.233176826,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,amitriptyline,DB00321
,115920,DB00327,10050584,49,6089,16,4246,0.007502177,2.135397659,1.191838456,4.028661552,0.028298016,DB0032710050584_,3.564963597,0.758652887,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,hydromorphone,DB00327
,115921,DB00863,10050584,105,10568,29,5811,0.000729665,1.990824431,1.307132208,3.120185695,0.004235698,DB0086310050584_,5.464207155,0.68854884,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,115924,DB00338,10055798,129,33545,111,22161,0.047214367,0.767779569,0.59071343,0.999241311,0.119854136,DB0033810055798_,2.121479812,-0.264252607,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,omeprazole,DB00338
,115925,DB00678,10055798,60,15539,37,10687,0.679048413,1.115298927,0.72772012,1.729675161,0.805741582,DB0067810055798_,0.215992206,0.109122465,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,losartan,DB00678
,115926,DB00863,10055798,47,10626,26,5814,1,0.989073515,0.599374077,1.665609067,1,DB0086310055798_,0,-0.010986617,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,ranitidine,DB00863
,115952,DB00363,10010144,30,4598,26,6862,0.054741163,1.721850824,0.982855009,3.035549822,0.133917025,DB0036310010144_,2.010534888,0.543399773,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,115953,DB00697,10000059,87,6009,15,1791,0.056652007,1.728549719,0.98947777,3.228734679,0.137206119,DB0069710000059_,1.986270965,0.547282744,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,tizanidine,DB00697
,115954,DB00814,10000059,165,8122,36,3379,0.00029412,1.906715791,1.31957849,2.822852651,0.001985604,DB0081410000059_,6.221831911,0.645382281,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,115972,DB00973,10038435,32,3819,35,2986,0.175660147,0.714905387,0.427407364,1.192011122,0.318164236,DB0097310038435_,1.145187564,-0.335605071,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,ezetimibe,DB00973
,115983,DB00472,10011224,147,10612,44,4268,0.090789452,1.343603232,0.951546671,1.930938412,0.196492446,DB0047210011224_,1.627131292,0.295354984,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,115984,DB00264,10013946,179,29428,103,24789,0.002186082,1.46389558,1.141725354,1.885338111,0.010463211,DB0026410013946_,4.559889916,0.381101088,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,115985,DB00425,10013946,81,12614,41,7443,0.453110807,1.165748489,0.790205611,1.74323809,0.620701354,DB0042510013946_,0.476905225,0.153363361,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,115986,DB00472,10013946,48,10711,17,4295,0.783398716,1.132193638,0.638623716,2.102518997,0.882133198,DB0047210013946_,0.125412216,0.124157023,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,115987,DB00736,10013946,122,10469,64,5489,1,0.999465709,0.731251071,1.377081072,1,DB0073610013946_,0,-0.000534434,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,115988,DB00761,10013946,84,15223,41,8584,0.513378242,1.155291354,0.785374143,1.723447036,0.673343833,DB0076110013946_,0.395499183,0.144352567,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,115989,DB00404,10013971,87,19805,33,9829,0.206978737,1.308428956,0.866477316,2.018626481,0.357600064,DB0040410013971_,1.028340056,0.268827147,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,115990,DB00425,10013971,53,12642,34,7450,0.738919785,0.918628449,0.58552714,1.458897935,0.849779265,DB0042510013971_,0.162778652,-0.084873537,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,115991,DB00404,10016825,131,19761,33,9829,0.000317003,1.974462636,1.338055189,2.989217795,0.002110484,DB0040410016825_,6.160838084,0.680296278,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,alprazolam,DB00404
,115992,DB00425,10016825,85,12610,20,7464,6.88475019317514e-05,2.515518448,1.530097766,4.327980166,0.00057872,DB0042510016825_,7.45469226,0.922478925,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,zolpidem,DB00425
,115993,DB00472,10016825,67,10692,14,4298,0.025800343,1.923703394,1.069253881,3.710447701,0.075246824,DB0047210016825_,2.586981579,0.654252179,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,fluoxetine,DB00472
,115994,DB00736,10016825,67,10524,26,5527,0.228251294,1.353331678,0.847692622,2.220876152,0.3837156,DB0073610016825_,0.957853625,0.302569462,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,esomeprazole,DB00736
,115995,DB00588,10022437,294,16230,135,8333,0.303612519,1.118129389,0.90730242,1.383707469,0.470171447,DB0058810022437_,0.754657869,0.111657101,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,116000,DB00761,10025197,37,15270,14,8611,0.243061694,1.490326256,0.786410966,2.986083414,0.401361768,DB0076110025197_,0.912892094,0.39899506,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,potassium chloride,DB00761
,116002,DB00455,10028735,87,9314,18,5100,5.27986163798477e-05,2.646397796,1.578012029,4.679014841,0.000462758,DB0045510028735_,7.678306038,0.973199393,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,116003,DB00472,10028735,43,10716,15,4297,0.77111426,1.149487408,0.625261351,2.23011154,0.874689322,DB0047210028735_,0.133886516,0.13931611,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,116004,DB00736,10028735,88,10503,25,5528,0.005270434,1.852602812,1.175111213,3.01940832,0.021329232,DB0073610028735_,3.84767677,0.616591576,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,116005,DB00455,10028810,184,9217,61,5057,0.000557279,1.654921156,1.229821105,2.253457737,0.003375911,DB0045510028810_,5.691089992,0.503753368,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,loratadine,DB00455
,116006,DB00472,10028810,112,10647,41,4271,0.653981024,1.095805117,0.758422166,1.610861033,0.78787658,DB0047210028810_,0.238413826,0.09148936,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,fluoxetine,DB00472
,116007,DB00736,10028810,165,10426,47,5506,0.000108315,1.853913583,1.331010591,2.625782538,0.000854076,DB0073610028810_,7.065490215,0.617298855,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,116008,DB00761,10028810,247,15060,94,8531,0.000960677,1.488460006,1.167281719,1.911140321,0.005330673,DB0076110028810_,5.234277697,0.397742032,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,116009,DB00455,10047924,54,9347,27,5091,0.81573718,1.089335808,0.673335363,1.801065923,0.901212667,DB0045510047924_,0.104014015,0.08556816,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,116011,DB00682,10047924,94,19365,35,16329,1.78326390419991e-05,2.264546587,1.520250678,3.443331883,0.000180489,DB0068210047924_,8.619838624,0.817374556,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,116012,DB01240,10047924,57,5694,8,1568,0.070105005,1.961861672,0.928776233,4.772450197,0.161428827,DB0124010047924_,1.823690931,0.673893855,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,116049,DB01240,10062355,185,5566,37,1539,0.081280546,1.382430027,0.962119863,2.034092899,0.180523429,DB0124010062355_,1.711894708,0.32384284,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,116051,DB08931,10017412,52,6525,15,2431,0.490118589,1.291511989,0.7144032,2.474846662,0.653466591,DB0893110017412_,0.425463871,0.255813617,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,riociguat,DB08931
,116066,DB00279,10013709,83,1154,24,192,0.03289211,0.5756471,0.351310196,0.97310461,0.091050405,DB0027910013709_,2.396342028,-0.55226048,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,liothyronine,DB00279
,116068,DB00091,10002034,74,5436,33,2637,0.755929499,1.087785252,0.710453484,1.697701466,0.863147622,DB0009110002034_,0.147169546,0.08414375,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,cyclosporine,DB00091
,116076,DB00264,10003671,24,29583,41,24851,0.005799921,0.491744545,0.284107437,0.833622416,0.023044506,DB0026410003671_,3.770327896,-0.709795915,NA,10003671,Atrioventricular block,10007541,Cardiac disorders,Card,metoprolol,DB00264
,116084,DB00668,10006093,46,10045,43,4260,0.000270184,0.453699276,0.292286481,0.705443149,0.001852078,DB0066810006093_,6.291447035,-0.790320689,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,epinephrine,DB00668
,116098,DB00813,10018100,40,10532,16,10152,0.002884884,2.409529684,1.318679204,4.612004201,0.013092054,DB0081310018100_,4.335749774,0.879431577,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,116120,DB08816,10020772,17,1134,33,1869,0.660203979,0.849061559,0.441399252,1.577138706,0.792537212,DB0881610020772_,0.232515819,-0.163623588,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ticagrelor,DB08816
,116124,DB00153,10013781,61,7362,13,3426,0.008142504,2.18349203,1.184808763,4.338354977,0.030225352,DB0015310013781_,3.499074243,0.780925444,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,116128,DB00153,10019303,46,7377,13,3426,0.123425819,1.643251738,0.871519522,3.319800435,0.246281089,DB0015310019303_,1.401281758,0.496677046,NA,10019303,Heart rate increased,10022891,Investigations,Inv,ergocalciferol,DB00153
,116131,DB01592,10019303,49,6227,12,3055,0.028435727,2.003175696,1.048161089,4.143965594,0.081236115,DB0159210019303_,2.510395361,0.694733769,NA,10019303,Heart rate increased,10022891,Investigations,Inv,iron,DB01592
,116135,DB00399,10020642,44,6948,28,4970,0.719398279,1.124089216,0.683270112,1.877722547,0.834354083,DB0039910020642_,0.181097406,0.116973122,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,zoledronic acid,DB00399
,116136,DB01592,10020642,45,6231,28,3039,0.31839259,0.783885548,0.47740802,1.307598812,0.486379353,DB0159210020642_,0.720766397,-0.243492253,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,iron,DB01592
,116143,DB00399,10022437,129,6863,69,4929,0.049930604,1.342686783,0.992296411,1.830011466,0.124874018,DB0039910022437_,2.080449909,0.294672669,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,zoledronic acid,DB00399
,116171,DB00316,10043458,44,65430,25,36928,1,0.993324279,0.594592492,1.693840482,1,DB0031610043458_,0,-0.006698103,NA,10043458,Thirst,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,116173,DB00451,10043458,44,47227,18,15401,0.460151968,0.797147575,0.45112337,1.466208348,0.627566776,DB0045110043458_,0.465905198,-0.226715454,NA,10043458,Thirst,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,116177,DB11093,10047895,47,1610,13,647,0.30979586,1.45272216,0.76686596,2.947111074,0.47725848,DB1109310047895_,0.739697048,0.373439148,NA,10047895,Weight decreased,10022891,Investigations,Inv,calcium citrate,DB11093
,116215,DB11089,10051792,36,10139,25,8382,0.522487664,1.190448895,0.694505455,2.070700493,0.681010004,DB1108910051792_,0.384178282,0.174330459,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,116218,DB00480,10043071,77,67351,67,67595,0.405405024,1.153415126,0.820331818,1.625177992,0.575055776,DB0048010043071_,0.553288241,0.142727216,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,116221,DB01307,10011224,34,2490,20,2049,0.271684756,1.398813316,0.779716487,2.573037294,0.434513771,DB0130710011224_,0.833527641,0.335624245,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin detemir,DB01307
,116231,DB06605,10019016,44,14029,49,12984,0.40617585,0.831078808,0.539941914,1.275786443,0.575754772,DB0660510019016_,0.552073452,-0.185030653,NA,10019016,Haemorrhagic stroke,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,116233,DB06605,10045555,34,14039,30,13003,0.900649392,1.049711831,0.623037283,1.776867748,0.95675912,DB0660510045555_,0.044203623,0.048515679,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,116234,DB00374,10029216,65,17651,11,5713,0.044561562,1.912421929,1.00062989,4.02207171,0.114704074,DB0037410029216_,2.165399737,0.648370465,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,treprostinil,DB00374
,116235,DB00695,10029216,99,27950,27,20501,1.19012711779686e-06,2.68937368,1.741693812,4.284686423,1.67107325273988e-05,DB0069510029216_,10.99945938,0.989308334,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,116237,DB00695,10043528,40,28009,13,20515,0.008198344,2.253614788,1.180443528,4.593393648,0.030400434,DB0069510043528_,3.493298391,0.8125355,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,116241,DB00331,10024570,40,24906,29,20723,0.62916724,1.147641743,0.693702577,1.920152949,0.768264467,DB0033110024570_,0.263621247,0.137709178,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,116243,DB00695,10024570,36,28013,17,20511,0.163769423,1.550516836,0.848386106,2.944607888,0.302443567,DB0069510024570_,1.195860575,0.438588318,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,116252,DB00331,10051792,49,24897,27,20725,0.08502474,1.510688849,0.925559806,2.51451438,0.186815543,DB0033110051792_,1.67763355,0.412565738,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,116254,DB00571,10016322,82,5041,28,2581,0.067698287,1.49936001,0.962877446,2.398813316,0.157202127,DB0057110016322_,1.850222871,0.405038357,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,116257,DB01156,10057362,37,13585,13,6315,0.448447976,1.323072582,0.686756432,2.714509304,0.616164939,DB0115610057362_,0.484240593,0.279956745,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,116264,DB01015,10035226,111,9776,130,9251,0.105127631,0.808003049,0.620440599,1.050788281,0.218735042,DB0101510035226_,1.519894137,-0.213189447,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sulfamethoxazole,DB01015
,116279,DB00904,10002511,102,22967,51,14405,0.211728333,1.254376387,0.887205597,1.793071995,0.363482414,DB0090410002511_,1.012024364,0.226638546,NA,10002511,Anhedonia,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,116284,DB00215,10012374,43,11060,14,5262,0.256497076,1.461257598,0.78332457,2.894686078,0.417331449,DB0021510012374_,0.873874532,0.379297434,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,116286,DB00316,10012374,165,65309,51,36902,9.06729820867069e-05,1.828049477,1.327590284,2.554964161,0.000734126,DB0031610012374_,7.216830186,0.603249539,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,116287,DB00472,10012374,43,10716,19,4293,0.778281424,0.906668321,0.51647825,1.649341482,0.87908243,DB0047210012374_,0.128876609,-0.097978583,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,116292,DB00904,10012374,52,23017,16,14440,0.01208978,2.038887713,1.145377293,3.827391548,0.041380282,DB0090410012374_,3.184950781,0.712404421,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,116293,DB01156,10012374,65,13557,21,6307,0.163768553,1.439961516,0.867886526,2.482387345,0.302443567,DB0115610012374_,1.195860575,0.364616388,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,116297,DB00215,10013496,53,11050,21,5255,0.534353587,1.200205795,0.710940966,2.097255927,0.690942741,DB0021510013496_,0.369698323,0.182493038,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,116313,DB00316,10028347,72,65402,36,36917,0.616532923,1.128942185,0.746482996,1.734730802,0.757634803,DB0031610028347_,0.277553799,0.121281075,NA,10028347,Muscle twitching,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,116320,DB00904,10028347,28,23041,30,14426,0.042940478,0.584391876,0.336242973,1.012643857,0.111582483,DB0090410028347_,2.192991207,-0.537183501,NA,10028347,Muscle twitching,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,116324,DB00620,10033425,105,4723,51,3081,0.097608374,1.34300342,0.949129689,1.921445637,0.207307378,DB0062010033425_,1.573552669,0.294908464,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,triamcinolone,DB00620
,116344,DB00904,10043224,35,23034,15,14441,0.246107395,1.462851818,0.778173368,2.884088566,0.405042444,DB0090410043224_,0.903763416,0.380387831,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,116360,DB00215,10043607,50,11053,24,5252,1,0.989927834,0.596280381,1.686112688,1,DB0021510043607_,0,-0.010123233,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,citalopram,DB00215
,116361,DB00281,10043607,75,11383,35,5636,0.839186473,1.060976214,0.700365485,1.635462166,0.91759293,DB0028110043607_,0.086001418,0.059189441,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,lidocaine,DB00281
,116366,DB00620,10048959,98,4730,41,3091,0.017797076,1.561912368,1.071001655,2.313981616,0.056381478,DB0062010048959_,2.875614586,0.445910947,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,116385,DB00316,10054196,82,65392,18,36935,9.83182808966471e-05,2.5730582,1.530869664,4.555961411,0.000785262,DB0031610054196_,7.149493613,0.945095152,NA,10054196,Affect lability,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,116398,DB00316,10061224,144,65330,58,36895,0.033162159,1.402128886,1.026595897,1.936755481,0.091648338,DB0031610061224_,2.389796434,0.337991714,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,116405,DB00904,10061224,54,23015,17,14439,0.014016291,1.99279548,1.137091085,3.668337208,0.046635216,DB0090410061224_,3.065399323,0.689538417,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,116430,DB00480,10029202,30,67398,31,67631,1,0.971081687,0.56778364,1.658668536,1,DB0048010029202_,0,-0.029344687,NA,10029202,Nervous system disorder,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,116432,DB01234,10029202,28,31597,30,32858,1,0.97057636,0.558579082,1.681558637,1,DB0123410029202_,0,-0.029865199,NA,10029202,Nervous system disorder,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,116441,DB00480,10002424,37,67391,35,67627,0.814776666,1.060869577,0.649913051,1.73479762,0.900608932,DB0048010002424_,0.104684153,0.059088928,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,116442,DB01234,10002424,27,31598,36,32852,0.377881564,0.77976923,0.455191598,1.321068633,0.547825102,DB0123410002424_,0.6017992,-0.248757262,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,116449,DB00338,10061024,164,33510,147,22125,0.007522466,0.73662382,0.585593818,0.927295903,0.028364369,DB0033810061024_,3.562621532,-0.305677938,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,omeprazole,DB00338
,116450,DB00005,10014004,58,128024,15,42404,0.498031025,1.280701865,0.716301659,2.433488869,0.660081963,DB0000510014004_,0.415391266,0.24740826,NA,10014004,Ear disorder,10013993,Ear and labyrinth disorders,Ear,etanercept,DB00005
,116454,DB06403,10013700,94,21377,17,6644,0.043245837,1.718463603,1.017332131,3.076344651,0.11214649,DB0640310013700_,2.187949313,0.541430637,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ambrisentan,DB06403
,116467,DB00204,10033557,32,932,33,1010,0.899829288,1.050848567,0.620130162,1.778749453,0.956571579,DB0020410033557_,0.044399659,0.049597997,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,dofetilide,DB00204
,116470,DB01222,10013971,73,9201,46,5359,0.703007632,0.924307801,0.629449301,1.36960435,0.821800601,DB0122210013971_,0.196257491,-0.078710145,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,116474,DB00598,10053762,38,1550,23,1005,0.894661415,1.071231027,0.617790409,1.895605205,0.955976233,DB0059810053762_,0.045022227,0.068808479,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,labetalol,DB00598
,116475,DB00497,10058080,65,19202,37,16338,0.05827569,1.494714319,0.98283854,2.303850487,0.140240467,DB0049710058080_,1.964396708,0.401935098,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,oxycodone,DB00497
,116484,DB00005,10057681,100,127982,18,42401,0.014095195,1.840483385,1.106932576,3.232251775,0.046853266,DB0000510057681_,3.060734559,0.610028246,NA,10057681,Joint arthroplasty,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,116489,DB06228,10003988,189,15723,147,15929,0.018243692,1.302544672,1.043200053,1.628971632,0.057456918,DB0622810003988_,2.856719868,0.264319791,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,rivaroxaban,DB06228
,116490,DB00761,10018985,31,15276,28,8597,0.077295616,0.623059552,0.361353181,1.078874211,0.173754834,DB0076110018985_,1.750109971,-0.473113176,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,116503,DB00635,10005728,55,32998,28,23766,0.148124617,1.414718921,0.881756541,2.316956595,0.281400373,DB0063510005728_,1.267976811,0.346930869,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,prednisone,DB00635
,116520,DB01175,10014380,32,10692,20,4872,0.294527261,0.729066919,0.40392941,1.3465683,0.460392594,DB0117510014380_,0.775675689,-0.315989755,NA,10014380,Electrocardiogram QRS complex prolonged,10022891,Investigations,Inv,escitalopram,DB01175
,116521,DB01175,10022523,42,10682,32,4860,0.032231778,0.597167252,0.367577128,0.978640714,0.089595207,DB0117510022523_,2.412453451,-0.515558051,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,116522,DB00316,10040741,35,65439,19,36934,1,1.039692399,0.578593243,1.924207507,1,DB0031610040741_,0,0.0389249,NA,10040741,Sinus bradycardia,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,116523,DB00678,10069326,57,15542,37,10687,0.833874416,1.059313672,0.687725457,1.649608661,0.913684982,DB0067810069326_,0.090269426,0.05762122,NA,10069326,Product substitution issue,10077536,Product issues,Prod,losartan,DB00678
,116525,DB01050,10038435,115,17993,82,9289,0.028565295,0.723997487,0.540069986,0.974377944,0.081528724,DB0105010038435_,2.506799882,-0.322967357,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,ibuprofen,DB01050
,116556,DB00060,10047340,50,9458,9,2456,0.418608123,1.442584661,0.701098282,3.341411648,0.587616262,DB0006010047340_,0.53168116,0.366436408,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,interferon beta-1a,DB00060
,116563,DB00073,10051313,36,7370,17,6390,0.038657211,1.835977522,1.003776766,3.489096714,0.102938384,DB0007310051313_,2.273624687,0.607577049,NA,10051313,B-lymphocyte count decreased,10022891,Investigations,Inv,rituximab,DB00073
,116572,DB00619,10000059,51,2848,42,2452,0.916529653,1.045446956,0.678614542,1.618220048,0.962734307,DB0061910000059_,0.037977807,0.044444503,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,imatinib,DB00619
,116573,DB00741,10000059,63,4031,34,3140,0.098834033,1.443299784,0.933840277,2.265552671,0.209082701,DB0074110000059_,1.565025406,0.366932009,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,hydrocortisone,DB00741
,116582,DB00341,10019974,50,11355,21,5047,0.897918982,1.058266865,0.62336445,1.857050636,0.956338178,DB0034110019974_,0.044643686,0.056632537,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,cetirizine,DB00341
,116584,DB00341,10040753,409,10996,105,4963,1.06730043991734e-07,1.758045925,1.411454205,2.205615769,1.92480219987838e-06,DB0034110040753_,13.16068735,0.564202923,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,cetirizine,DB00341
,116586,DB01234,10040753,287,31338,168,32720,1.80974348551944e-09,1.783641156,1.46833763,2.172333173,4.76405683694327e-08,DB0123410040753_,16.85958116,0.578656868,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,116587,DB01233,10038695,52,3369,23,1703,0.624870799,1.142810883,0.684436859,1.963530634,0.764509819,DB0123310038695_,0.26852041,0.133490914,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoclopramide,DB01233
,116590,DB06273,10021097,37,5058,36,1374,1.63397781713715e-07,0.279236885,0.17095031,0.456603017,2.83305454640171e-06,DB0627310021097_,12.77415508,-1.275694807,male,10021097,Hypotension,10047065,Vascular disorders,Vasc,tocilizumab,DB06273
,116603,DB00581,10002855,42,2071,18,2051,0.002571451,2.310494081,1.296341727,4.278791492,0.011929155,DB0058110002855_,4.428769878,0.837461389,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,lactulose,DB00581
,116604,DB00213,10022116,44,18851,17,13404,0.036649933,1.840324157,1.029950756,3.437137011,0.098880522,DB0021310022116_,2.313843003,0.609941729,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,116607,DB00231,10033371,142,3154,50,2089,0.000114189,1.880818713,1.346589948,2.663983714,0.000893957,DB0023110033371_,7.019852967,0.631707168,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,116608,DB00581,10033371,92,2021,52,2017,0.001209287,1.765482132,1.235696973,2.545428843,0.00644422,DB0058110033371_,5.04457172,0.568423816,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,lactulose,DB00581
,116634,DB00540,10013700,169,2314,32,1059,1.26039286241532e-06,2.41646053,1.635368001,3.671405669,1.75846212253645e-05,DB0054010013700_,10.94848583,0.882303879,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,nortriptyline,DB00540
,116638,DB06228,10037660,157,15755,122,15954,0.030325138,1.303124959,1.020958738,1.666526346,0.085388928,DB0622810037660_,2.46053884,0.264765195,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,116642,DB00331,10018836,40,24906,42,20710,0.318293828,0.791937935,0.500314595,1.251723356,0.486288661,DB0033110018836_,0.72095288,-0.233272255,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,116643,DB00588,10018836,41,16483,16,8452,0.402280492,1.313994761,0.721046074,2.509725159,0.572074701,DB0058810018836_,0.5584857,0.273071933,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,116649,DB00169,10009866,38,38653,13,18162,0.369491463,1.373505274,0.71545853,2.810791752,0.539125877,DB0016910009866_,0.617806198,0.317366066,NA,10009866,Cold sweat,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,116674,DB01020,10010774,38,1775,40,1838,1,0.983720796,0.610960186,1.581518589,1,DB0102010010774_,0,-0.016413166,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,isosorbide mononitrate,DB01020
,116675,DB01020,10012735,89,1724,80,1798,0.386352559,1.160204245,0.841664875,1.601480314,0.556499274,DB0102010012735_,0.586089412,0.148596063,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,isosorbide mononitrate,DB01020
,116689,DB00207,10046571,108,8972,24,5431,1.90584842820153e-06,2.723799031,1.735085802,4.440189039,2.53775207372225e-05,DB0020710046571_,10.58164679,1.002027609,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,azithromycin,DB00207
,116690,DB01020,10046571,53,1760,30,1848,0.007459776,1.854681051,1.15748262,3.021622504,0.028170422,DB0102010046571_,3.569482726,0.617712741,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,isosorbide mononitrate,DB01020
,116691,DB08910,10046571,288,16456,121,17367,9.45053175227134e-19,2.511877875,2.022162032,3.135872095,8.7313612340405e-17,DB0891010046571_,36.9770253,0.921030631,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,116716,DB00169,10064882,40,38651,12,18163,0.183552062,1.566399093,0.805383265,3.280671439,0.328353758,DB0016910064882_,1.113663721,0.448779413,NA,10064882,Procedural pain,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,116751,DB00327,10037377,83,6055,36,4226,0.018768141,1.609056655,1.073503196,2.455240988,0.058770985,DB0032710037377_,2.83410699,0.475648079,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydromorphone,DB00327
,116752,DB00335,10027175,96,8370,36,5429,0.005291166,1.729603275,1.165923936,2.616545047,0.021399952,DB0033510027175_,3.844366618,0.547892061,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,116757,DB00635,10034972,54,32999,13,23781,0.000156616,2.993406202,1.611751514,5.98035468,0.0011705,DB0063510034972_,6.750324225,1.096411937,female,10034972,Photosensitivity reaction,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,116758,DB00335,10037153,115,8351,49,5416,0.015547316,1.522050973,1.078395019,2.17617268,0.050702381,DB0033510037153_,2.981782398,0.42005875,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,atenolol,DB00335
,116770,DB00153,10002855,146,7277,33,3406,8.92357516081851e-05,2.070647194,1.407686115,3.127060253,0.000724386,DB0015310002855_,7.230186217,0.727861213,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ergocalciferol,DB00153
,116776,DB00331,10030041,42,24904,19,20733,0.028266216,1.84025575,1.046642196,3.351286173,0.080850697,DB0033110030041_,2.515151066,0.609904556,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,metformin,DB00331
,116777,DB00635,10030041,62,32991,28,23766,0.041993996,1.595107642,1.005164434,2.589996782,0.109684722,DB0063510030041_,2.210145197,0.466941221,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,prednisone,DB00635
,116779,DB00331,10033433,68,24878,29,20723,0.002091155,1.953149503,1.246846309,3.130907378,0.010093284,DB0033110033433_,4.595885047,0.6694432,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,116799,DB08932,10000081,423,19020,95,6502,0.00015469,1.522056777,1.213451542,1.925619923,0.001157914,DB0893210000081_,6.761134998,0.420062563,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,116802,DB00761,10003445,73,15234,66,8559,0.005882333,0.621407834,0.438828436,0.881447095,0.023305017,DB0076110003445_,3.759086627,-0.475767675,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,116811,DB08932,10008629,75,19368,38,6559,0.050431464,0.668402463,0.446172614,1.01627252,0.12580164,DB0893210008629_,2.073048897,-0.402864797,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,macitentan,DB08932
,116812,DB11089,10008629,32,10143,23,8384,0.684688142,1.150008194,0.651686992,2.059679283,0.809582898,DB1108910008629_,0.211236105,0.139769068,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,docusate,DB11089
,116816,DB00213,10009657,55,18840,24,13397,0.051446339,1.629562241,0.991378082,2.754192732,0.127738531,DB0021310009657_,2.05776983,0.488311415,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,116825,DB00887,10010774,43,2298,36,1779,0.732718971,0.924698811,0.577314266,1.488823344,0.844808341,DB0088710010774_,0.168645493,-0.078287204,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,bumetanide,DB00887
,116828,DB11365,10012174,51,1594,39,1509,0.337257347,1.237875321,0.794773606,1.94133296,0.506415846,DB1136510012174_,0.680397118,0.213396459,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,sennosides,DB11365
,116829,DB11365,10012735,107,1538,60,1488,0.000823005,1.725058351,1.235288876,2.427769508,0.004688319,DB1136510012735_,5.362681153,0.545260877,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sennosides,DB11365
,116830,DB00341,10020919,47,11358,12,5056,0.090304627,1.74344719,0.909651515,3.61384491,0.195725179,DB0034110020919_,1.63104375,0.555864297,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,cetirizine,DB00341
,116835,DB00341,10017944,59,11346,29,5039,0.64464167,0.903567204,0.569228901,1.463839829,0.780618245,DB0034110017944_,0.247669051,-0.101404789,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,116837,DB00404,10017944,81,19811,19,9843,0.001968719,2.118082617,1.272261745,3.700062438,0.009610963,DB0040410017944_,4.644850807,0.750511254,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,116840,DB08932,10017944,160,19283,54,6543,1,1.005376345,0.733199169,1.397184571,1,DB0893210017944_,0,0.005361944,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,116841,DB11089,10017944,47,10128,29,8378,0.248293622,1.340630705,0.825626494,2.210932372,0.407657818,DB1108910017944_,0.897327137,0.293140179,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,116843,DB00887,10019211,151,2190,62,1753,9.62538999518501e-06,1.949170722,1.430770002,2.682074504,0.000105199,DB0088710019211_,9.159657629,0.667404011,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,bumetanide,DB00887
,116844,DB04854,10019211,25,756,34,1452,0.212068156,1.412063178,0.801190955,2.457687331,0.363863781,DB0485410019211_,1.01097571,0.345051882,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,febuxostat,DB04854
,116845,DB11365,10019211,49,1596,25,1523,0.01298232,1.86998702,1.126293302,3.176342752,0.043833047,DB1136510019211_,3.12736724,0.62593149,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sennosides,DB11365
,116850,DB00451,10021518,55,47216,6,15413,0.006697833,2.992402531,1.290084145,8.507184479,0.02586498,DB0045110021518_,3.654865362,1.096076587,female,10021518,Impaired gastric emptying,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,116855,DB00904,10021518,52,23017,23,14433,0.191272431,1.417683939,0.85196926,2.428146779,0.338191857,DB0090410021518_,1.08414192,0.349024511,NA,10021518,Impaired gastric emptying,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,116861,DB00341,10033318,59,11346,27,5041,0.906966986,0.97087331,0.605121506,1.594678966,0.95853111,DB0034110033318_,0.04235326,-0.029559293,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,cetirizine,DB00341
,116865,DB11089,10033318,41,10134,34,8373,1,0.996334445,0.616284517,1.620250017,1,DB1108910033318_,0,-0.003672289,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,docusate,DB11089
,116867,DB00193,10037423,82,19238,38,8664,0.921281,0.971826798,0.653271869,1.469099704,0.965141033,DB0019310037423_,0.03548104,-0.028577682,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,116868,DB00341,10037423,45,11360,10,5058,0.055729622,2.003536575,0.99440827,4.462299431,0.135590606,DB0034110037423_,1.998115183,0.694913907,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,116869,DB00390,10037423,57,4088,27,3274,0.02678045,1.690630457,1.049180158,2.786986975,0.077511878,DB0039010037423_,2.557324091,0.525101511,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,116870,DB00887,10037423,48,2293,29,1786,0.298761061,1.289122543,0.79289242,2.129377521,0.464739428,DB0088710037423_,0.766278401,0.253961788,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bumetanide,DB00887
,116871,DB00904,10037423,132,22937,69,14387,0.244945615,1.199894293,0.88947664,1.631020549,0.403737098,DB0090410037423_,0.906991362,0.182233464,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,116873,DB11089,10037423,59,10116,33,8374,0.074595182,1.479968115,0.949683177,2.342344977,0.16917557,DB1108910037423_,1.776818227,0.392020543,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,116875,DB01069,10038695,60,6640,32,2363,0.07380879,0.667295313,0.426326115,1.062135664,0.16788859,DB0106910038695_,1.784454675,-0.404522584,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,promethazine,DB01069
,116879,DB00761,10039163,108,15199,37,8588,0.008999785,1.649265101,1.124634314,2.467601948,0.032716872,DB0076110039163_,3.419864367,0.500329795,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,116880,DB00904,10039163,54,23015,18,14438,0.020689491,1.881957397,1.086039952,3.411403855,0.063475141,DB0090410039163_,2.757106938,0.632312404,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,ondansetron,DB00904
,116884,DB00341,10048294,32,11373,19,5049,0.361556621,0.74769376,0.410671956,1.397611631,0.531398798,DB0034110048294_,0.632242507,-0.290761797,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,cetirizine,DB00341
,116886,DB01240,10048294,47,5704,17,1559,0.358168368,0.755672452,0.42452667,1.407902127,0.527878861,DB0124010048294_,0.638888452,-0.280147262,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,epoprostenol,DB01240
,116889,DB01240,10061428,338,5413,78,1498,0.176330049,1.199178845,0.92823105,1.564830158,0.319104963,DB0124010061428_,1.142235193,0.181637026,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,epoprostenol,DB01240
,116890,DB11365,10061428,54,1591,51,1497,1,0.996266796,0.662129929,1.500828875,1,DB1136510061428_,0,-0.00374019,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,sennosides,DB11365
,116931,DB00295,10061024,29,14634,47,9555,0.000133497,0.40288586,0.244323288,0.654060894,0.00101962,DB0029510061024_,6.888325285,-0.909101983,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,morphine,DB00295
,116932,DB00471,10061024,55,14134,33,5432,0.055443669,0.640551811,0.408152518,1.019462812,0.135063655,DB0047110061024_,2.002009096,-0.445425269,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,montelukast,DB00471
,116941,DB00213,10003997,35,18860,24,13397,1,1.035914048,0.598607599,1.821141075,1,DB0021310003997_,0,0.035284175,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,116946,DB00003,10008479,32,2966,49,2544,0.013095851,0.560208888,0.346056001,0.895575054,0.044151151,DB0000310008479_,3.120136293,-0.579445551,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,dornase alfa,DB00003
,116956,DB00003,10022000,76,2922,77,2516,0.32523154,0.849898124,0.607925464,1.187988873,0.493629317,DB0000310022000_,0.705970415,-0.16263879,NA,10022000,Influenza,10021881,Infections and infestations,Infec,dornase alfa,DB00003
,116957,DB00332,10022000,34,2650,16,1640,0.464320711,1.315002261,0.703693715,2.559949235,0.631450223,DB0033210022000_,0.459736164,0.273838385,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ipratropium,DB00332
,116959,DB00425,10022000,117,12578,62,7422,0.53444153,1.1135455,0.810444408,1.542616115,0.691005466,DB0042510022000_,0.369607546,0.107549069,NA,10022000,Influenza,10021881,Infections and infestations,Infec,zolpidem,DB00425
,116961,DB01104,10022000,132,15331,38,7248,0.00633932,1.642212719,1.135757318,2.424864429,0.024748112,DB0110410022000_,3.699006074,0.496044551,NA,10022000,Influenza,10021881,Infections and infestations,Infec,sertraline,DB01104
,116972,DB01104,10038687,35,15428,21,7265,0.391105577,0.784863858,0.443973046,1.419957821,0.560947813,DB0110410038687_,0.578127402,-0.242245006,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,116986,DB00698,10011906,78,3070,29,400,1.29933705681841e-05,0.350588782,0.223016394,0.564368857,0.000136694,DB0069810011906_,8.897763404,-1.048141303,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,nitrofurantoin,DB00698
,116987,DB00737,10011906,100,2701,50,882,0.020429665,0.653173257,0.456411311,0.944781,0.062843036,DB0073710011906_,2.76711516,-0.42591286,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,meclizine,DB00737
,116988,DB00972,10011906,43,2461,37,1142,0.007453736,0.539360892,0.337389197,0.866069364,0.028151656,DB0097210011906_,3.570149093,-0.617370373,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,azelastine,DB00972
,117010,DB00654,10035664,93,3723,86,2512,0.04438335,0.729694067,0.535877478,0.994523152,0.114368546,DB0065410035664_,2.168329181,-0.315129919,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,latanoprost,DB00654
,117011,DB01162,10035664,6,267,66,1636,0.221859718,0.557168699,0.195398626,1.296489703,0.375850193,DB0116210035664_,0.978564637,-0.584887213,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,terazosin,DB01162
,117012,DB00115,10043554,118,18307,79,10393,0.265045196,0.847978565,0.631675624,1.143492216,0.427025834,DB0011510043554_,0.850910766,-0.164899921,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,cyanocobalamin,DB00115
,117013,DB00656,10043554,47,11966,33,6586,0.293267067,0.783920436,0.491198793,1.264328801,0.458881738,DB0065610043554_,0.778962754,-0.243447749,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,trazodone,DB00656
,117015,DB00341,10047943,34,11371,17,5051,0.761315023,0.88841342,0.482213874,1.697421297,0.867650712,DB0034110047943_,0.141966051,-0.118318082,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,cetirizine,DB00341
,117016,DB00588,10047943,52,16472,30,8438,0.640485576,0.887931775,0.555523366,1.442761013,0.777426154,DB0058810047943_,0.251766618,-0.118860369,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,117027,DB00338,10009866,32,33642,20,22252,0.888166079,1.05830237,0.586841581,1.952983864,0.953646495,DB0033810009866_,0.047462226,0.056666086,NA,10009866,Cold sweat,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,117035,DB00331,10038687,30,24916,39,20713,0.069700402,0.639485883,0.383485612,1.056658442,0.160764748,DB0033110038687_,1.827813175,-0.447090734,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,117039,DB04854,10005483,20,761,43,1443,0.688888261,0.881982791,0.487803869,1.544886905,0.812447693,DB0485410005483_,0.207703745,-0.125582734,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,febuxostat,DB04854
,117043,DB04854,10016256,35,746,59,1427,0.580115952,1.134681964,0.717695603,1.77089334,0.72869727,DB0485410016256_,0.316496901,0.126352404,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,febuxostat,DB04854
,117053,DB00169,10043521,97,38594,24,18151,0.00336319,1.90080192,1.205293116,3.109541128,0.014826237,DB0016910043521_,4.211356892,0.64227586,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,117064,DB00588,10020993,37,16487,25,8443,0.284972242,0.757943687,0.443892827,1.314464361,0.449555598,DB0058810020993_,0.799495744,-0.277146188,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,fluticasone propionate,DB00588
,117081,DB00047,10020642,72,9213,61,8457,0.664001397,1.083432045,0.758576443,1.551767142,0.795391547,DB0004710020642_,0.228920774,0.080133822,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,insulin glargine,DB00047
,117085,DB00047,10033318,36,9249,19,8499,0.057742889,1.741033104,0.971695626,3.215982665,0.139225963,DB0004710033318_,1.97165703,0.554478675,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,insulin glargine,DB00047
,117103,DB00047,10064355,113,9172,118,8400,0.353416029,0.877031702,0.67034474,1.146976743,0.52320095,DB0004710064355_,0.647789663,-0.131212139,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,117131,DB08895,10015150,195,27919,29,6617,0.016873853,1.593636197,1.074050493,2.445073059,0.054088931,DB0889510015150_,2.917125713,0.466018322,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,117132,DB00169,10020751,393,38298,114,18061,2.55483021789895e-06,1.625735796,1.315476284,2.022338308,3.28139322147441e-05,DB0016910020751_,10.32465737,0.485960511,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,cholecalciferol,DB00169
,117133,DB08895,10037087,326,27788,44,6602,0.000241772,1.760239657,1.280382554,2.472735139,0.001686622,DB0889510037087_,6.385027563,0.565449968,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,117134,DB00158,10042682,69,16746,15,8089,0.003361338,2.221926358,1.257510104,4.185324141,0.014823048,DB0015810042682_,4.211572029,0.798374548,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,117135,DB08895,10042682,87,28027,7,6639,0.002317014,2.944026911,1.368937357,7.542570051,0.010965557,DB0889510042682_,4.512996133,1.079778342,female,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,117155,DB00421,10068319,69,8834,16,5236,0.000409645,2.555911896,1.466193331,4.724005863,0.00261443,DB0042110068319_,5.946709254,0.938409066,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,117158,DB00169,10022094,82,38609,11,18164,9.93227771657252e-06,3.506779687,1.86030132,7.301295205,0.000107925,DB0016910022094_,9.134076526,1.254698148,female,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,117163,DB01225,10003658,61,4983,80,4560,0.041209517,0.697803178,0.490440226,0.988548916,0.108124592,DB0122510003658_,2.224471086,-0.359818196,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,enoxaparin,DB01225
,117170,DB01225,10028372,44,5000,54,4586,0.156202067,0.747374358,0.489225359,1.136259251,0.292371384,DB0122510028372_,1.229730422,-0.29118907,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,enoxaparin,DB01225
,117174,DB00958,10042128,48,4546,20,2565,0.309883657,1.354102843,0.786525699,2.414295921,0.477323796,DB0095810042128_,0.7395602,0.303139127,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,carboplatin,DB00958
,117175,DB01229,10042128,61,5680,12,2697,0.003501754,2.41348018,1.283926179,4.933089528,0.015331083,DB0122910042128_,4.177872947,0.881069764,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,paclitaxel,DB01229
,117179,DB01225,10061428,85,4959,62,4578,0.183053354,1.26560355,0.899222633,1.789877673,0.327718119,DB0122510061428_,1.115601434,0.235549123,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,enoxaparin,DB01225
,117192,DB01296,10013709,60,1389,23,960,0.016731845,1.802572275,1.089189483,3.07769364,0.053695932,DB0129610013709_,2.92441803,0.589214686,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,glucosamine,DB01296
,117193,DB00158,10038153,81,16734,51,8053,0.136643278,0.764354151,0.53130065,1.108512528,0.265018894,DB0015810038153_,1.327954158,-0.268724049,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,folic acid,DB00158
,117194,DB00563,10038153,32,46614,24,15324,0.002935262,0.438325559,0.250102325,0.777960207,0.013272554,DB0056310038153_,4.322056964,-0.824793359,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,methotrexate,DB00563
,117195,DB01068,10038153,38,13725,19,6821,1,0.993951734,0.558501594,1.826767448,1,DB0106810038153_,0,-0.00606663,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,clonazepam,DB01068
,117198,DB00316,10056812,126,65348,42,36911,0.002816004,1.694503432,1.186119375,2.464309063,0.012834866,DB0031610056812_,4.355589899,0.527389737,NA,10056812,Body height decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,117250,DB00203,10060933,100,13778,37,8901,0.003616797,1.745984163,1.185205995,2.622155028,0.01573054,DB0020310060933_,4.152151253,0.557318387,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,117257,DB00736,10013950,95,10496,36,5517,0.097164921,1.387049359,0.934522845,2.099179172,0.206557478,DB0073610013950_,1.577176559,0.327178728,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,117259,DB06403,10013950,56,21415,16,6645,0.889743696,1.086034321,0.61370153,2.029771981,0.954236817,DB0640310013950_,0.046843402,0.082532824,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,117277,DB08935,10013968,38,494,61,752,0.831689657,0.948327399,0.605170875,1.470363938,0.912067678,DB0893510013968_,0.092041083,-0.053055479,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,obinutuzumab,DB08935
,117280,DB08904,10065154,83,11527,15,3544,0.056068632,1.701129898,0.972772407,3.179605503,0.136201737,DB0890410065154_,1.993618128,0.531292676,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,certolizumab pegol,DB08904
,117285,DB00734,10029282,64,3986,93,4809,0.258932988,0.830278383,0.592543668,1.15724153,0.420010096,DB0073410029282_,0.86747653,-0.185994233,NA,10029282,Neuroleptic malignant syndrome,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,117286,DB00734,10048294,28,4022,40,4862,0.542135682,0.846211983,0.501814314,1.409018078,0.6973995,DB0073410048294_,0.360396862,-0.166985379,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,117296,DB00108,10050584,41,10153,10,3285,0.514662239,1.326513984,0.65254118,2.97340507,0.67450623,DB0010810050584_,0.393774367,0.282554437,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,natalizumab,DB00108
,117306,DB00563,10049438,34,46612,18,15330,0.108072758,0.621233366,0.341018929,1.168767268,0.223166976,DB0056310049438_,1.499835019,-0.476048477,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,117307,DB00635,10049438,90,32963,59,23735,0.61822589,1.098403293,0.781933885,1.552856479,0.759105174,DB0063510049438_,0.275614941,0.093857574,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,117328,DB00635,10041569,74,32979,28,23766,0.0033851,1.904519401,1.217356463,3.057575184,0.014911574,DB0063510041569_,4.205617605,0.644229694,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,117334,DB00887,10028596,17,2324,34,1781,0.000984493,0.383261752,0.20012774,0.708002958,0.005434586,DB0088710028596_,5.214972022,-0.959037098,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,bumetanide,DB00887
,117336,DB00169,10054236,147,38544,70,18105,0.941893382,0.986418176,0.736740201,1.331471816,0.981065069,DB0016910054236_,0.019116493,-0.0136749,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,117345,DB00451,10058267,43,47228,16,15403,0.650880874,0.876524159,0.483593165,1.667552774,0.785329528,DB0045110058267_,0.241651869,-0.131791012,NA,10058267,Troponin increased,10022891,Investigations,Inv,levothyroxine,DB00451
,117356,DB01076,10014625,49,25698,67,25516,0.094437027,0.726171166,0.491656267,1.065933112,0.202420066,DB0107610014625_,1.597410209,-0.319969526,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,117362,DB01076,10019465,31,25716,30,25553,1,1.026788226,0.601021002,1.756474749,1,DB0107610019465_,0,0.026435703,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,117386,DB00480,10047899,635,66793,594,67068,0.21800531,1.073390119,0.957805019,1.203146292,0.371203575,DB0048010047899_,0.991004648,0.070821976,NA,10047899,Weight increased,10022891,Investigations,Inv,lenalidomide,DB00480
,117387,DB00563,10019465,34,46612,31,15317,6.82218447813951e-05,0.360414132,0.214849099,0.606636762,0.000574103,DB0056310019465_,7.462701473,-1.020501543,male,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,117388,DB00563,10029350,77,46569,85,15263,3.80985348006408e-14,0.29691142,0.215130974,0.409231756,2.0626570282901e-12,DB0056310029350_,26.90702614,-1.214321434,male,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,117396,DB00563,10021015,63,46583,56,15292,1.65524092524923e-07,0.369315632,0.253430776,0.539391014,2.86614016601949e-06,DB0056310021015_,12.76254432,-0.996103629,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,117398,DB00563,10074903,179,46467,39,15309,0.018193523,1.512087345,1.063932282,2.197803194,0.057333264,DB0056310074903_,2.858874302,0.413491044,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,117399,DB00559,10005750,51,9608,15,3291,0.672859362,1.164575517,0.643546737,2.23306233,0.801436847,DB0055910005750_,0.221349104,0.152356657,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,bosentan,DB00559
,117400,DB00016,10019211,67,2695,40,2250,0.115934715,1.398329371,0.927350462,2.132486499,0.235062017,DB0001610019211_,1.447905898,0.335278218,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,erythropoietin,DB00016
,117401,DB00008,10061428,51,1474,56,1620,1,1.000920442,0.666592503,1.500032398,1,DB0000810061428_,0,0.000920019,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,peginterferon alfa-2a,DB00008
,117403,DB06292,10012735,47,1310,34,1199,0.311591615,1.26510611,0.790546663,2.043246355,0.479025691,DB0629210012735_,0.736001048,0.235156,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dapagliflozin,DB06292
,117412,DB01050,10013946,145,17963,55,9316,0.051460408,1.367262628,0.99481199,1.902528915,0.127751227,DB0105010013946_,2.057670447,0.312810659,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,117426,DB00497,10005425,33,19234,18,16357,0.159182518,1.559082344,0.852364136,2.94209536,0.296388219,DB0049710005425_,1.216085134,0.444097407,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,oxycodone,DB00497
,117444,DB00338,10062060,59,33615,24,22248,0.043654889,1.627025997,0.99633887,2.735815276,0.112900946,DB0033810062060_,2.181244432,0.486753807,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,117468,DB01373,10013496,69,22651,7,7374,0.001162963,3.208997952,1.475990717,8.280695253,0.006242285,DB0137310013496_,5.076408984,1.165958724,female,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,calcium,DB01373
,117471,DB00169,10061422,45,38646,61,18114,8.8419388362519e-08,0.345781016,0.229792497,0.516890436,1.61845656205349e-06,DB0016910061422_,13.3340376,-1.061949606,male,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,117477,DB00635,10040943,98,32955,46,23748,0.01760898,1.535218426,1.070504827,2.230223963,0.055944444,DB0063510040943_,2.883396148,0.428672668,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,117489,DB00009,10018985,104,1247,93,1458,0.075755333,1.307369383,0.968387046,1.767053129,0.171075127,DB0000910018985_,1.765652481,0.268017014,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,alteplase,DB00009
,117492,DB01065,10016322,104,4227,37,3014,0.000190306,2.004020133,1.360558025,3.010168564,0.001381628,DB0106510016322_,6.584492629,0.69515523,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,117509,DB00423,10010264,66,2401,22,1018,0.407868192,1.271856291,0.769760245,2.177106067,0.577319086,DB0042310010264_,0.549360156,0.24047748,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,methocarbamol,DB00423
,117511,DB01067,10010264,62,4299,35,4788,0.00141081,1.972762188,1.280249308,3.083548154,0.007303425,DB0106710010264_,4.919411842,0.679434687,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,117512,DB00207,10013971,37,9043,17,5438,0.40030394,1.308795216,0.717948507,2.481152508,0.570189344,DB0020710013971_,0.56178679,0.269107032,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,117515,DB01104,10013971,62,15401,22,7264,0.291970871,1.329249159,0.804922676,2.272661368,0.457425382,DB0110410013971_,0.782141508,0.284614241,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,117518,DB06228,10013971,147,15765,74,16002,4.85996489156229e-07,2.016294932,1.513343216,2.706008009,7.56506382258315e-06,DB0622810013971_,11.79196977,0.701261635,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,117519,DB13961,10013971,41,9416,29,6385,0.903062779,0.958668048,0.580829904,1.601358935,0.957326661,DB1396110013971_,0.043610607,-0.042210408,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,117533,DB01067,10018884,40,4321,64,4759,0.075082296,0.688383107,0.450720703,1.040205706,0.16997142,DB0106710018884_,1.772124973,-0.373409754,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,glipizide,DB01067
,117561,DB00213,10002948,41,18854,30,13391,0.904589408,0.970658272,0.591128984,1.610796497,0.957573483,DB0021310002948_,0.043352816,-0.029780807,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,117562,DB00264,10002948,56,29551,26,24866,0.010759036,1.812352642,1.118869533,3.007591796,0.037747098,DB0026410002948_,3.276846675,0.594625804,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,117565,DB00787,10002948,29,16971,30,17218,1,0.980733652,0.567701412,1.691785117,1,DB0078710002948_,0,-0.019454363,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,117566,DB01076,10002948,53,25694,48,25535,0.690688667,1.097315882,0.728140112,1.657414627,0.813421373,DB0107610002948_,0.20650601,0.09286709,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,117592,DB00051,10011906,274,25457,247,11173,1.47264640798994e-15,0.486869887,0.407863933,0.581487459,9.70138116140741e-14,DB0005110011906_,29.96392304,-0.719758364,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,117593,DB00204,10011906,62,902,102,941,0.006997383,0.634270453,0.448811871,0.89059326,0.026782122,DB0020410011906_,3.620020715,-0.455279834,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dofetilide,DB00204
,117594,DB05259,10060800,47,11223,11,2717,1,1.034399782,0.527900911,2.214743505,1,DB0525910060800_,0,0.033821338,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,glatiramer,DB05259
,117599,DB00950,10017885,53,4665,13,2043,0.060234039,1.785321853,0.957477517,3.578373255,0.143892731,DB0095010017885_,1.938687181,0.579598709,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,fexofenadine,DB00950
,117600,DB05351,10017885,73,2650,31,1100,0.913308855,0.97748543,0.629786619,1.549220671,0.961184788,DB0535110017885_,0.039588601,-0.022771892,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,dexlansoprazole,DB05351
,117601,DB00051,10013538,70,25661,31,11389,1,1.002186152,0.647441401,1.583925031,1,DB0005110013538_,0,0.002183766,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,adalimumab,DB00051
,117604,DB01067,10013710,30,4331,38,4785,0.626784461,0.872244131,0.520907016,1.448522463,0.766280445,DB0106710013710_,0.26620706,-0.136685927,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,117607,DB00736,10033661,31,10560,22,5531,0.310648469,0.738080575,0.413335498,1.339228158,0.478053629,DB0073610033661_,0.738032358,-0.30370228,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,esomeprazole,DB00736
,117608,DB00959,10033661,55,8023,53,4949,0.02214665,0.640175074,0.43016464,0.953459112,0.066964764,DB0095910033661_,2.703588715,-0.446013587,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,methylprednisolone,DB00959
,117611,DB00736,10037153,105,10486,33,5520,0.008912087,1.674911249,1.121397136,2.561309345,0.032460916,DB0073610037153_,3.427718495,0.515760178,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,esomeprazole,DB00736
,117612,DB00959,10037153,55,8023,19,4983,0.030172748,1.797813707,1.048960474,3.211954865,0.085076547,DB0095910037153_,2.46420388,0.586571319,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,methylprednisolone,DB00959
,117613,DB01067,10037153,67,4294,34,4789,0.000179145,2.197581301,1.430494802,3.432149427,0.001313845,DB0106710037153_,6.634797387,0.787357347,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,glipizide,DB01067
,117614,DB00524,10070863,36,1541,27,1317,0.701804759,1.139464697,0.668741222,1.962802556,0.821013333,DB0052410070863_,0.197215929,0.130558588,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,metolazone,DB00524
,117615,DB00959,10070863,55,8023,49,4953,0.068136583,0.692984842,0.462075453,1.041848121,0.157947797,DB0095910070863_,1.845490698,-0.366747153,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,methylprednisolone,DB00959
,117621,DB01373,10044055,64,22656,7,7374,0.003302022,2.975820569,1.363191142,7.701131985,0.014619627,DB0137310044055_,4.225390324,1.090519822,female,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,117623,DB06643,10065687,106,52315,8,7507,0.087765178,1.901305209,0.930089703,4.520039236,0.191454197,DB0664310065687_,1.653106681,0.642540603,NA,10065687,Bone loss,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,117631,DB00811,10003481,20,2778,34,4122,0.677901571,0.872811348,0.475012666,1.564111482,0.804780398,DB0081110003481_,0.217185837,-0.136035843,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,ribavirin,DB00811
,117640,DB00341,10041349,157,11248,61,5007,0.416452919,1.145687214,0.84551246,1.569387755,0.58568566,DB0034110041349_,0.53497205,0.136004644,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,117646,DB00051,10008469,84,25647,37,11383,1,1.007623684,0.67630041,1.527275523,1,DB0005110008469_,0,0.007594771,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,117649,DB00575,10022998,34,5210,32,3797,0.318344788,0.774369721,0.462720751,1.298713452,0.486324117,DB0057510022998_,0.720879969,-0.255705844,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,clonidine,DB00575
,117657,DB00091,10044565,52,5458,20,2650,0.449041504,1.262292655,0.739004995,2.237198462,0.616685699,DB0009110044565_,0.483395787,0.232929635,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,cyclosporine,DB00091
,117660,DB01222,10000059,110,9164,27,5378,1.62410235596517e-05,2.390790364,1.55532123,3.795411823,0.00016601,DB0122210000059_,8.70346115,0.871624008,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,117661,DB01050,10040829,55,18053,19,9352,0.14102285,1.49954048,0.875520058,2.677192348,0.271310932,DB0105010040829_,1.304489765,0.405158715,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,117666,DB00115,10013754,40,18385,17,10455,0.33769579,1.338034329,0.741093466,2.518232438,0.506838187,DB0011510013754_,0.679563485,0.291201618,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,117667,DB00169,10013754,72,38619,24,18151,0.155254947,1.410022692,0.87725455,2.341608899,0.291148023,DB0016910013754_,1.233923469,0.343605798,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,117669,DB00656,10020937,157,11856,41,6578,6.39742025052861e-06,2.124494386,1.495874294,3.078074386,7.34146218228092e-05,DB0065610020937_,9.519387435,0.753533838,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,117671,DB00476,10065154,127,17130,33,6144,0.105252086,1.380284277,0.933667246,2.093249264,0.218959327,DB0047610065154_,1.518869289,0.322289475,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,duloxetine,DB00476
,117672,DB00656,10065154,59,11954,29,6590,0.656454902,1.121577891,0.706773361,1.816601485,0.789956965,DB0065610065154_,0.23577681,0.114736525,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,trazodone,DB00656
,117694,DB08880,10049848,75,3263,18,791,1,1.010060756,0.593568736,1.806566771,1,DB0888010049848_,0,0.010010483,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,teriflunomide,DB08880
,117713,DB00455,10033433,48,9353,11,5107,0.006224045,2.382544283,1.218797141,5.092877932,0.024374109,DB0045510033433_,3.714233799,0.868168943,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,117715,DB00455,10047513,74,9327,37,5081,0.764914856,1.089527487,0.723558903,1.665961891,0.870286203,DB0045510047513_,0.138933153,0.085744104,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,loratadine,DB00455
,117731,DB00005,10040979,73,128009,45,42374,0.001334926,0.537016221,0.365338209,0.796962268,0.006984875,DB0000510040979_,4.964008209,-0.621726978,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,117744,DB00404,10022004,145,19747,31,9831,5.55165625714266e-06,2.328585876,1.569971792,3.554698261,6.47837002082108e-05,DB0040410022004_,9.644456526,0.845261163,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,117748,DB00404,10036790,80,19812,25,9837,0.047935774,1.58883237,1.002320302,2.600892127,0.121232085,DB0040410036790_,2.110048516,0.462999388,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,117750,DB00448,10037087,97,5048,30,3094,0.000833777,1.981610038,1.300287859,3.100241879,0.004739045,DB0044810037087_,5.351919688,0.683909665,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,lansoprazole,DB00448
,117753,DB00448,10068319,51,5094,21,3103,0.143622071,1.479292705,0.872139527,2.594469037,0.274993162,DB0044810068319_,1.291009047,0.391564071,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lansoprazole,DB00448
,117766,DB00451,10007636,42,47229,24,15395,0.031607246,0.570445017,0.337450665,0.985179411,0.088237104,DB0045110007636_,2.42772772,-0.561338491,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,117779,DB00451,10041569,70,47201,19,15400,0.539086521,1.202018447,0.715393164,2.114757887,0.694926029,DB0045110041569_,0.363949871,0.184002183,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,117786,DB00470,10047895,34,885,51,902,0.095897303,0.679615,0.422539375,1.081162928,0.204615684,DB0047010047895_,1.586621772,-0.386228818,NA,10047895,Weight decreased,10022891,Investigations,Inv,dronabinol,DB00470
,117787,DB00687,10047895,22,964,33,1052,0.275502508,0.727636548,0.401142801,1.296255452,0.438791391,DB0068710047895_,0.823731171,-0.317953602,NA,10047895,Weight decreased,10022891,Investigations,Inv,fludrocortisone,DB00687
,117788,DB00829,10047895,158,7894,68,4386,0.092255825,1.290969439,0.963102708,1.745957087,0.198831122,DB0082910047895_,1.615299447,0.255393439,NA,10047895,Weight decreased,10022891,Investigations,Inv,diazepam,DB00829
,117790,DB00829,10061428,107,7945,56,4398,0.805009766,1.057686394,0.756846255,1.491953377,0.894473299,DB0082910061428_,0.111520227,0.056083875,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,diazepam,DB00829
,117791,DB00381,10015967,85,29275,27,22860,2.14945355218225e-05,2.458214488,1.57737489,3.94485466,0.000212447,DB0038110015967_,8.45681601,0.899435269,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,amlodipine,DB00381
,117802,DB09270,10012378,48,3066,25,2343,0.123902518,1.467139441,0.883865473,2.490857432,0.246941251,DB0927010012378_,1.398604819,0.383314546,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ubidecarenone,DB09270
,117822,DB00482,10042772,37,8222,19,3052,0.290571318,0.722883917,0.404477661,1.33292962,0.455844052,DB0048210042772_,0.785604519,-0.324506627,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,117823,DB01261,10042772,22,3759,40,3263,0.004815287,0.477472843,0.269677513,0.824904641,0.019861877,DB0126110042772_,3.918953116,-0.739247994,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,sitagliptin,DB01261
,117828,DB08908,10028411,47,10626,18,3261,0.462921177,0.801334201,0.455955588,1.468191758,0.630118048,DB0890810028411_,0.4618481,-0.221477189,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,dimethyl fumarate,DB08908
,117844,DB00635,10047943,114,32939,69,23725,0.261315105,1.189993983,0.874434957,1.629678378,0.422856376,DB0063510047943_,0.860722695,0.173948251,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,prednisone,DB00635
,117847,DB00019,10015150,72,18940,16,9513,0.002071199,2.260160513,1.300930019,4.165860113,0.010012226,DB0001910015150_,4.603948373,0.815435834,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,pegfilgrastim,DB00019
,117848,DB00958,10018884,81,4513,33,2552,0.116708725,1.387929828,0.912350165,2.154900495,0.236175905,DB0095810018884_,1.443178391,0.327813305,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,carboplatin,DB00958
,117849,DB00958,10035528,178,4416,49,2536,2.15912946092231e-06,2.085950004,1.506529212,2.934791461,2.83480109292423e-05,DB0095810035528_,10.47095369,0.735224389,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,carboplatin,DB00958
,117850,DB01229,10035528,129,5612,39,2670,0.012230802,1.573610786,1.088649831,2.320064073,0.04179765,DB0122910035528_,3.174915153,0.453372842,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,paclitaxel,DB01229
,117862,DB01255,10060933,30,2103,25,1553,0.681681866,0.886193213,0.501577271,1.578293597,0.807528608,DB0125510060933_,0.213776797,-0.120820279,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,lisdexamfetamine,DB01255
,117863,DB08868,10011906,59,9143,32,2479,0.002842304,0.49992093,0.319024727,0.796514208,0.012937909,DB0886810011906_,4.347593607,-0.693305332,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,117881,DB00035,10021036,68,602,65,477,0.311003466,0.829062011,0.568576155,1.209648684,0.478515883,DB0003510021036_,0.737065875,-0.187460324,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,desmopressin,DB00035
,117884,DB00983,10048959,48,3453,24,1716,1,0.993918284,0.594616564,1.70251987,1,DB0098310048959_,0,-0.006100285,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,formoterol,DB00983
,117889,DB00451,10060800,297,46974,37,15382,6.25657576812337e-10,2.628607338,1.862556107,3.808569859,1.80223664728902e-08,DB0045110060800_,17.83165227,0.966454177,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,117892,DB00190,10013710,50,3247,59,4615,0.378223568,1.204466427,0.807185936,1.791133004,0.548245318,DB0019010013710_,0.601032432,0.18603667,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,117897,DB00227,10037087,51,2416,26,1777,0.161937954,1.442616316,0.878886262,2.420652313,0.299988662,DB0022710037087_,1.204010599,0.366458351,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,lovastatin,DB00227
,117920,DB01015,10028116,33,9854,51,9330,0.028721394,0.612670699,0.382623129,0.968832662,0.0818693,DB0101510028116_,2.5026312,-0.489927683,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,117922,DB00153,10029354,44,7379,26,3413,0.366657848,0.782787895,0.47054397,1.326610314,0.536301245,DB0015310029354_,0.623059251,-0.244893508,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,ergocalciferol,DB00153
,117923,DB06769,10029354,42,625,42,1014,0.038104967,1.621864457,1.019243451,2.581136496,0.101813374,DB0676910029354_,2.28461381,0.483576387,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,bendamustine,DB06769
,117924,DB00153,10043554,38,7385,27,3412,0.107474731,0.650268644,0.386017881,1.109451902,0.222377558,DB0015310043554_,1.503378631,-0.430369704,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,ergocalciferol,DB00153
,117925,DB01015,10043554,121,9766,200,9181,8.52010995047351e-07,0.568780762,0.449195147,0.717726748,1.2452103978215e-05,DB0101510043554_,11.29362096,-0.564260224,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,sulfamethoxazole,DB01015
,117940,DB00316,10065553,35,65439,32,36921,0.05565198,0.6170726,0.370989165,1.029727161,0.135445583,DB0031610065553_,1.999185318,-0.482768596,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,117941,DB01015,10065553,46,9841,44,9337,1,0.991912159,0.640992628,1.536604448,1,DB0101510065553_,0,-0.008120725,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,sulfamethoxazole,DB01015
,117962,DB01075,10047924,109,19839,53,11044,0.459791194,1.144888941,0.816513525,1.622523462,0.627204916,DB0107510047924_,0.466481972,0.135307637,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,117968,DB00441,10043645,51,2223,53,1841,0.273108378,0.796956386,0.528994862,1.199701372,0.43608746,DB0044110043645_,0.82991246,-0.226955324,NA,10043645,Thrombotic microangiopathy,10005329,Blood and lymphatic system disorders,Blood,gemcitabine,DB00441
,117978,DB08932,10017577,272,19171,87,6510,0.669026627,1.061651382,0.829576624,1.369930987,0.799026053,DB0893210017577_,0.224361727,0.059825603,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,117979,DB08932,10058080,91,19352,28,6569,0.751313257,1.103201411,0.714615139,1.752418207,0.859573395,DB0893210058080_,0.151319065,0.098216326,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,117989,DB00136,10013573,40,2052,45,1637,0.123089447,0.709191767,0.44900093,1.116571266,0.245834847,DB0013610013573_,1.403095321,-0.343629314,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,calcitriol,DB00136
,117990,DB00136,10028813,126,1966,83,1599,0.152586576,1.234619168,0.920743553,1.662507576,0.287590968,DB0013610028813_,1.246216059,0.210762557,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,calcitriol,DB00136
,117991,DB00626,10037844,75,792,23,423,0.026121748,1.740925229,1.060486258,2.956040635,0.076002895,DB0062610037844_,2.576983848,0.554416713,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,bacitracin,DB00626
,118000,DB01075,10007515,231,19717,178,10919,0.001253624,0.718711655,0.587653225,0.880098284,0.006625645,DB0107510007515_,5.016807502,-0.330295038,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,118006,DB00559,10028391,44,9615,13,3293,0.761035063,1.159166624,0.612277049,2.348881889,0.867486573,DB0055910028391_,0.142155245,0.147701319,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bosentan,DB00559
,118037,DB00684,10013573,34,2758,17,2331,0.089612808,1.690184824,0.915650029,3.234936154,0.194594792,DB0068410013573_,1.63683587,0.524837886,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,tobramycin,DB00684
,118038,DB00684,10019211,78,2714,41,2307,0.015173704,1.616992111,1.089323721,2.431423339,0.049768008,DB0068410019211_,3.000382901,0.480567702,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,tobramycin,DB00684
,118039,DB00684,10047700,41,2751,24,2324,0.16903354,1.443068377,0.84860647,2.504724641,0.309544474,DB0068410047700_,1.172653501,0.366771664,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,tobramycin,DB00684
,118053,DB00836,10010774,175,5360,90,3985,0.00545427,1.445580801,1.110847605,1.891799583,0.021926358,DB0083610010774_,3.820065818,0.368511179,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,118060,DB00571,10013709,262,4861,115,2494,0.18040053,1.16889507,0.92997494,1.476332008,0.324345185,DB0057110013709_,1.125946944,0.156058918,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,118073,DB00555,10047340,38,7009,19,3467,1,0.98929674,0.555414721,1.819596874,1,DB0055510047340_,0,-0.010760952,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,lamotrigine,DB00555
,118080,DB00331,10060933,99,24847,73,20679,0.444052032,1.128649768,0.825263541,1.549701024,0.612039939,DB0033110060933_,0.490957739,0.121022022,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,118082,DB00678,10002424,40,15559,130,10594,3.36162001463045e-21,0.209517441,0.143052469,0.301004452,3.99819828436929e-19,DB0067810002424_,42.36327294,-1.562948291,male,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,118084,DB00222,10010264,46,3160,31,3097,0.109931891,1.454195843,0.899808541,2.379115875,0.225981314,DB0022210010264_,1.487302963,0.374453063,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,118085,DB00678,10010264,286,15313,94,10630,4.89554563567546e-11,2.112015369,1.665072941,2.699174683,1.67769774489869e-09,DB0067810010264_,20.20584337,0.747642643,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,118086,DB01307,10010264,50,2474,21,2048,0.008115561,1.970668332,1.15778243,3.466265563,0.030140237,DB0130710010264_,3.501894215,0.67837274,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,insulin detemir,DB01307
,118087,DB00678,10047899,264,15335,113,10611,1.41536979898048e-05,1.616552042,1.29017098,2.036253134,0.000147455,DB0067810047899_,8.821984861,0.480295512,NA,10047899,Weight increased,10022891,Investigations,Inv,losartan,DB00678
,118089,DB01115,10007515,54,3546,50,2218,0.053252179,0.675600698,0.449464304,1.017069321,0.131104156,DB0111510007515_,2.031763189,-0.392153061,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,nifedipine,DB01115
,118095,DB00421,10028596,59,8844,54,5198,0.024068706,0.642212074,0.435651631,0.94833502,0.071400704,DB0042110028596_,2.639447546,-0.442836696,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,spironolactone,DB00421
,118096,DB00421,10040070,47,8856,46,5206,0.017346888,0.600679531,0.390795875,0.923710334,0.055283287,DB0042110040070_,2.895284641,-0.509693713,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,spironolactone,DB00421
,118097,DB00999,10040070,30,21400,28,12211,0.074716259,0.611404936,0.352786089,1.062552128,0.1693981,DB0099910040070_,1.775503715,-0.491995797,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,118112,DB00555,10013710,149,6898,129,3357,3.9107928052285e-06,0.562117916,0.439464551,0.719870379,4.76344712166038e-05,DB0055510013710_,9.951953874,-0.576043637,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,118113,DB01018,10022998,15,397,37,742,0.456455151,0.75787899,0.381499941,1.435264054,0.623819666,DB0101810022998_,0.471893948,-0.27723155,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,guanfacine,DB01018
,118116,DB00177,10033557,61,4739,14,2836,0.000675205,2.60719912,1.438452012,5.056828748,0.003974862,DB0017710033557_,5.527765233,0.958276511,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,valsartan,DB00177
,118123,DB00480,10028391,134,67294,100,67562,0.026013116,1.345328846,1.030379536,1.761366699,0.075745033,DB0048010028391_,2.580382404,0.296638478,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,118126,DB00531,10071066,73,7179,40,6476,0.010665786,1.646223507,1.102910856,2.488855249,0.037477467,DB0053110071066_,3.284015401,0.498483881,NA,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,118127,DB01234,10071066,84,31541,25,32863,3.38377125287816e-09,3.501089516,2.216613374,5.714034386,8.44657430027564e-08,DB0123410071066_,16.28691979,1.25307421,female,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,118128,DB00619,10037844,143,2756,76,2418,0.000515859,1.650663867,1.234101154,2.222351259,0.003167704,DB0061910037844_,5.754748217,0.50117755,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,imatinib,DB00619
,118135,DB00046,10029331,61,5398,46,4646,0.558922162,1.141330189,0.764022975,1.715341247,0.711751806,DB0004610029331_,0.340026016,0.132194414,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,insulin lispro,DB00046
,118136,DB00047,10029331,78,9207,66,8452,0.675606018,1.084866122,0.770521879,1.531478859,0.803379592,DB0004710029331_,0.21892796,0.081456589,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,118137,DB00668,10013700,314,9777,43,4260,9.38604889880354e-16,3.18145226,2.302780321,4.493795442,6.29368100267987e-14,DB0066810013700_,30.39664519,1.157337778,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,epinephrine,DB00668
,118143,DB00404,10020765,57,19835,26,9836,0.815571975,1.087140659,0.672008766,1.802605926,0.901141583,DB0040410020765_,0.104092894,0.083551001,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,118150,DB00575,10024264,52,5192,46,3783,0.355702259,0.823680775,0.541921287,1.255502098,0.52542268,DB0057510024264_,0.643552235,-0.193972233,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,118163,DB06218,10043071,45,1649,8,1428,2.39942596978052e-06,4.869061232,2.261747304,12.00035916,3.10514264421841e-05,DB0621810043071_,10.37986581,1.582901153,female,10043071,Tachycardia,10007541,Cardiac disorders,Card,lacosamide,DB06218
,118258,DB00425,10020937,166,12529,65,7419,0.004867848,1.512220596,1.126911791,2.049916409,0.020029393,DB0042510020937_,3.910554415,0.413579164,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,118260,DB00451,10027374,59,47212,13,15406,0.219722919,1.48092925,0.802736722,2.944418042,0.373101,DB0045110027374_,0.985906118,0.392669762,NA,10027374,Mental impairment,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,118271,DB11365,10021097,34,1611,42,1506,0.246715455,0.756830913,0.464274864,1.22580454,0.405776412,DB1136510021097_,0.901952981,-0.278615415,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sennosides,DB11365
,118277,DB00904,10040752,68,23001,55,14401,0.164464609,0.774109053,0.534205771,1.126094948,0.30338636,DB0090410040752_,1.192748169,-0.25604252,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,ondansetron,DB00904
,118286,DB00186,10049848,121,16780,64,9944,0.492650136,1.120418184,0.820000422,1.543124234,0.655556268,DB0018610049848_,0.422271139,0.113701995,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,118287,DB01238,10049848,36,5214,23,3479,0.894954377,1.044378272,0.600998442,1.849447367,0.955976233,DB0123810049848_,0.045022227,0.043421753,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,118294,DB00404,10061422,44,19848,47,9815,0.000306655,0.462948088,0.299545344,0.714276113,0.002054135,DB0040410061422_,6.187900667,-0.770140353,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,118306,DB00682,10043071,130,19329,80,16284,0.031033377,1.368990871,1.027468448,1.833481851,0.086995394,DB0068210043071_,2.441900103,0.314073878,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,warfarin,DB00682
,118308,DB01015,10027417,17,9870,38,9343,0.002715858,0.423498089,0.223982561,0.769322687,0.012461607,DB0101510027417_,4.385102794,-0.859206278,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,sulfamethoxazole,DB01015
,118312,DB00586,10007882,33,7076,31,2774,0.00068854,0.417360843,0.247243349,0.706122124,0.004037541,DB0058610007882_,5.512119373,-0.873804099,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,diclofenac,DB00586
,118315,DB00318,10053762,39,4244,13,1826,0.543434518,1.290679263,0.67251706,2.641822098,0.698629381,DB0031810053762_,0.358634891,0.255168641,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,codeine,DB00318
,118317,DB06724,10053762,284,7645,72,3847,6.30084652687957e-08,1.984760907,1.522710371,2.615492345,1.19235241871152e-06,DB0672410053762_,13.63958238,0.685498457,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium carbonate,DB06724
,118320,DB00887,10033425,69,2272,33,1782,0.020078283,1.63977464,1.062587071,2.57620304,0.061957931,DB0088710033425_,2.781299654,0.494558817,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,bumetanide,DB00887
,118325,DB00047,10048959,162,9123,107,8411,0.008105909,1.395827755,1.084633528,1.802221281,0.030110771,DB0004710048959_,3.502872345,0.333487612,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,118326,DB00887,10048959,85,2256,75,1740,0.417074085,0.874143689,0.629006629,1.216819972,0.58621423,DB0088710048959_,0.534069976,-0.134510513,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,118350,DB06643,10012601,69,52352,10,7505,1,0.98915942,0.506520271,2.154831328,1,DB0664310012601_,0,-0.010899767,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,denosumab,DB06643
,118364,DB06643,10048592,78,52343,13,7502,0.633315084,0.859955262,0.474451918,1.687637351,0.771948665,DB0664310048592_,0.258837227,-0.150874913,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,118365,DB01060,10000087,101,8486,33,5048,0.002195588,1.820563786,1.215953284,2.789941263,0.010495066,DB0106010000087_,4.556850057,0.599146226,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,118367,DB01060,10020642,50,8537,35,5046,0.433608205,0.844409005,0.536550898,1.342102611,0.602096815,DB0106010020642_,0.507337025,-0.169118298,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,amoxicillin,DB01060
,118387,DB00776,10003549,45,1860,25,1314,0.390825749,1.271520232,0.758857587,2.175359066,0.56068414,DB0077610003549_,0.578597563,0.240213218,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,oxcarbazepine,DB00776
,118392,DB00996,10040829,129,38824,56,22369,0.078891487,1.327229484,0.96227294,1.851069544,0.176474426,DB0099610040829_,1.73457931,0.283093675,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,118396,DB11089,10040829,43,10132,24,8383,0.139998337,1.482352951,0.878763958,2.556108094,0.269842069,DB1108910040829_,1.309918419,0.393630657,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,docusate,DB11089
,118411,DB00996,10019708,57,38896,8,22417,2.38690396811757e-05,4.106287156,1.948852429,9.968897041,0.000232069,DB0099610019708_,8.368477145,1.412519252,female,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,gabapentin,DB00996
,118422,DB00572,10019211,102,2800,55,2071,0.070702378,1.371615952,0.973544662,1.950014569,0.162521975,DB0057210019211_,1.816942054,0.315989572,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,atropine,DB00572
,118425,DB00388,10021097,45,591,41,509,0.823023323,0.945351187,0.594626899,1.506330574,0.906059659,DB0038810021097_,0.098650126,-0.056198794,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,phenylephrine,DB00388
,118437,DB00563,10047942,204,46442,97,15251,0.003201816,0.690635394,0.539322279,0.889477202,0.014266778,DB0056310047942_,4.249821686,-0.370143244,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,methotrexate,DB00563
,118444,DB01068,10038695,119,13644,52,6788,0.463855653,1.138512753,0.814187496,1.611205711,0.631078977,DB0106810038695_,0.460324263,0.129722808,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,118448,DB00051,10006784,98,25633,28,11392,0.041843597,1.555477947,1.012454222,2.461201915,0.109422369,DB0005110006784_,2.212539942,0.44178286,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,118453,DB00051,10047571,139,25592,54,11366,0.434710568,1.143195926,0.828516115,1.597195134,0.603197344,DB0005110047571_,0.505510866,0.133827784,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,adalimumab,DB00051
,118456,DB00319,10010264,41,1351,40,1813,0.172663795,1.375362961,0.862390527,2.19501002,0.314341865,DB0031910010264_,1.157274142,0.318717668,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,piperacillin,DB00319
,118465,DB14500,10005724,130,7679,41,4032,0.004363475,1.664785193,1.161074876,2.43161045,0.018321714,DB1450010005724_,3.999668349,0.509696102,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,potassium,DB14500
,118470,DB00829,10018884,35,8017,19,4435,1,1.019050589,0.566421606,1.888133723,1,DB0082910018884_,0,0.018871399,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,diazepam,DB00829
,118471,DB00334,10021097,68,2781,92,2720,0.045276091,0.72296263,0.518080847,1.004708191,0.116116895,DB0033410021097_,2.153157877,-0.324397745,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,olanzapine,DB00334
,118473,DB00829,10021097,116,7936,77,4377,0.225505104,0.830909993,0.616019876,1.125996164,0.380278543,DB0082910021097_,0.966851286,-0.185233802,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,diazepam,DB00829
,118474,DB01069,10021097,130,6570,47,2348,0.931474749,0.988504554,0.700461395,1.415837342,0.972488084,DB0106910021097_,0.027897457,-0.011562029,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,promethazine,DB01069
,118477,DB00682,10029366,27,19432,32,16332,0.193303865,0.709159166,0.408552927,1.222381898,0.340811757,DB0068210029366_,1.076424986,-0.343675284,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,warfarin,DB00682
,118481,DB00863,10029366,38,10635,17,5823,0.572751584,1.223840456,0.673577812,2.314578993,0.722760866,DB0086310029366_,0.324676863,0.201993829,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,ranitidine,DB00863
,118486,DB00787,10035528,391,16609,445,16803,0.09975417,0.888918203,0.772656114,1.022373006,0.210427498,DB0078710035528_,1.558614114,-0.117750058,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,acyclovir,DB00787
,118487,DB00829,10035528,36,8016,22,4432,0.783615696,0.904745695,0.517263276,1.616575075,0.882171087,DB0082910035528_,0.125369266,-0.100101375,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,diazepam,DB00829
,118488,DB01225,10035528,58,4986,69,4571,0.153100432,0.770639656,0.532669136,1.111528236,0.288331652,DB0122510035528_,1.243643893,-0.260534387,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,enoxaparin,DB01225
,118489,DB14500,10035528,117,7692,72,4001,0.279597088,0.845266963,0.623258426,1.152998677,0.443417972,DB1450010035528_,0.813242451,-0.168102769,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,potassium,DB14500
,118490,DB00472,10013911,42,10717,9,4303,0.088809993,1.873653736,0.897991149,4.381664294,0.193274526,DB0047210013911_,1.643643684,0.627890394,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,118502,DB01175,10013916,37,10687,18,4874,0.884298747,0.937478546,0.519754277,1.751045396,0.951814769,DB0117510013916_,0.049384833,-0.064561406,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,118504,DB00715,10017577,83,4760,30,2257,0.223594496,1.311840414,0.851725893,2.07009868,0.378026715,DB0071510017577_,0.972790411,0.271431047,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,118518,DB00555,10007515,118,6929,72,3414,0.161686234,0.807535231,0.59548921,1.10143938,0.299680757,DB0055510007515_,1.205037513,-0.213768595,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,lamotrigine,DB00555
,118519,DB00818,10007515,81,1339,97,1580,0.938404526,0.985351844,0.717669898,1.350056337,0.978144719,DB0081810007515_,0.022097646,-0.0147565,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,propofol,DB00818
,118520,DB00683,10013710,45,1539,74,1564,0.01171005,0.618081033,0.414050283,0.913911151,0.040369684,DB0068310013710_,3.209676183,-0.481135709,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,midazolam,DB00683
,118521,DB00818,10013710,47,1373,119,1558,2.76783537446685e-06,0.44830668,0.310280255,0.638793815,3.52825183403789e-05,DB0081810013710_,10.25212295,-0.802277728,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,propofol,DB00818
,118525,DB00813,10014625,72,10500,36,10132,0.001339907,1.929836027,1.275021012,2.967550217,0.007004666,DB0081310014625_,4.961178789,0.657435039,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,118529,DB00722,10040108,46,25357,45,25987,0.834607012,1.047635392,0.67901386,1.617199013,0.91418995,DB0072210040108_,0.089716907,0.046535617,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,118530,DB00818,10040108,38,1382,112,1565,1.37870808669065e-07,0.384348195,0.256862945,0.564292591,2.4354396544801e-06,DB0081810040108_,12.92538326,-0.95620638,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,propofol,DB00818
,118538,DB00572,10043554,23,2879,32,2094,0.01927368,0.522852413,0.291205672,0.924870659,0.060063867,DB0057210043554_,2.812346826,-0.648456047,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,atropine,DB00572
,118539,DB00472,10000087,103,10656,30,4282,0.124222499,1.379573248,0.909363542,2.150346497,0.247390868,DB0047210000087_,1.39678573,0.321774211,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,118540,DB00060,10010264,54,9454,22,2443,0.086188499,0.634304969,0.379045774,1.096046984,0.188678663,DB0006010010264_,1.667709906,-0.455225417,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,118563,DB00678,10020646,27,15572,70,10654,5.07247717183992e-10,0.263910646,0.162590971,0.417151647,1.48639980447951e-08,DB0067810020646_,18.02432379,-1.332144696,male,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,118591,DB00398,10033425,60,667,97,1441,0.092637807,1.336211455,0.939107268,1.888761332,0.199444043,DB0039810033425_,1.612221567,0.289838337,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sorafenib,DB00398
,118598,DB00563,10054112,148,46498,37,15311,0.146939953,1.317112576,0.912954759,1.944107742,0.279715866,DB0056310054112_,1.273980956,0.275441899,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,methotrexate,DB00563
,118599,DB00620,10054112,40,4788,24,3108,0.798590163,1.081873785,0.634990472,1.8801028,0.891240524,DB0062010054112_,0.11514094,0.078694524,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,triamcinolone,DB00620
,118601,DB00316,10003504,39,65435,24,36929,0.793210336,0.917089889,0.537740569,1.594484196,0.887894288,DB0031610003504_,0.118902588,-0.086549787,NA,10003504,Aspiration,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,118606,DB00230,10016330,49,19625,16,8635,0.346367683,1.347434629,0.752771447,2.540147438,0.515793697,DB0023010016330_,0.662048406,0.29820251,NA,10016330,Feeling drunk,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,118610,DB00316,10039897,94,65380,80,36873,0.007199669,0.662709259,0.486444334,0.904601385,0.02737895,DB0031610039897_,3.597980797,-0.411418908,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,118616,DB00635,10011655,50,33003,29,23765,0.36435392,1.241522501,0.770300217,2.035512543,0.533986216,DB0063510011655_,0.627385253,0.21633845,NA,10011655,Cushingoid,10014698,Endocrine disorders,Endo,prednisone,DB00635
,118625,DB00959,10018651,28,8050,30,4972,0.041597854,0.576511746,0.331418072,0.99987793,0.108932903,DB0095910018651_,2.217023158,-0.550759565,NA,10018651,Graft versus host disease,10021428,Immune system disorders,Immun,methylprednisolone,DB00959
,118635,DB01024,10028813,128,2083,55,2065,1.39540761192756e-07,2.306747051,1.658489454,3.244031363,2.45915448069164e-06,DB0102410028813_,12.91569297,0.835838329,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,mycophenolic acid,DB01024
,118636,DB00196,10037087,85,4998,24,3261,0.000154129,2.310584104,1.450727021,3.810683925,0.001154211,DB0019610037087_,6.764338203,0.837500352,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,fluconazole,DB00196
,118644,DB01015,10042682,48,9839,37,9344,0.384628307,1.232015189,0.784956953,1.947612089,0.554684391,DB0101510042682_,0.589355993,0.208651194,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,118650,DB00635,10061494,30,33023,36,23758,0.045077259,0.599550915,0.356555311,1.001468024,0.115725522,DB0063510061494_,2.156534084,-0.51157438,NA,10061494,Rhinovirus infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,118671,DB00425,10005724,56,12639,18,7466,0.022091982,1.837716087,1.063362403,3.32426034,0.066835587,DB0042510005724_,2.705519602,0.608523544,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,zolpidem,DB00425
,118674,DB00836,10005724,48,5487,21,4054,0.04999804,1.688677867,0.99008491,2.974233053,0.1249951,DB0083610005724_,2.079480743,0.523945895,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,loperamide,DB00836
,118678,DB00264,10021027,70,29537,27,24865,0.000460787,2.182430363,1.38124768,3.541198505,0.00288479,DB0026410021027_,5.84830326,0.780439101,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,118679,DB00264,10044066,39,29568,31,24861,0.904567724,1.057803486,0.642974498,1.753976689,0.957573483,DB0026410044066_,0.043352816,0.056194575,NA,10044066,Torsade de pointes,10007541,Cardiac disorders,Card,metoprolol,DB00264
,118692,DB00275,10021097,45,2015,45,1192,0.015049008,0.591688419,0.380048041,0.921134553,0.049451578,DB0027510021097_,3.006761308,-0.524775102,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,olmesartan,DB00275
,118694,DB00343,10021143,104,8632,55,5040,0.619925466,1.104059312,0.787269629,1.563002579,0.760529501,DB0034310021143_,0.273740377,0.098993671,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,118695,DB00472,10021143,37,10722,18,4294,0.549846968,0.823256784,0.456389478,1.53786796,0.704186687,DB0047210021143_,0.350711778,-0.194487117,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,118698,DB00343,10022523,47,8689,29,5066,0.812362785,0.944924797,0.581678314,1.55892142,0.899071824,DB0034310022523_,0.106392355,-0.056649935,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,118706,DB00472,10038695,43,10716,28,4284,0.048328398,0.613963619,0.372221142,1.027668264,0.121937914,DB0047210038695_,2.104243263,-0.487819605,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,118759,DB00869,10013709,76,1229,43,886,0.251310308,1.274032588,0.855913447,1.91718125,0.411249272,DB0086910013709_,0.888555747,0.242187136,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dorzolamide,DB00869
,118762,DB00215,10010071,34,11069,27,5249,0.053782035,0.597160655,0.349327369,1.030243756,0.132099311,DB0021510010071_,2.024201281,-0.515569099,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,118764,DB01075,10010071,60,19888,54,11043,0.010822139,0.616937138,0.419649938,0.908929578,0.037922934,DB0107510010071_,3.272199234,-0.482988144,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,118765,DB00215,10012373,35,11068,30,5246,0.022857072,0.552967314,0.329452338,0.933531725,0.068556871,DB0021510012373_,2.680091643,-0.592456387,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,118767,DB01075,10012373,42,19906,43,11054,0.006168014,0.542387106,0.345728697,0.850407018,0.024194337,DB0107510012373_,3.721636702,-0.611775314,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,118774,DB01224,10027417,70,8038,26,5891,0.002517066,1.973073327,1.240019151,3.22931201,0.011722372,DB0122410027417_,4.446256118,0.679592392,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,quetiapine,DB01224
,118778,DB01224,10038678,42,8066,11,5906,0.001238511,2.795473508,1.412962929,6.026090073,0.006563359,DB0122410038678_,5.026252834,1.028001505,female,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,quetiapine,DB01224
,118779,DB00557,10070863,358,5629,302,2765,5.24116999897978e-11,0.582308702,0.494815948,0.685636019,1.78682429861457e-09,DB0055710070863_,20.14282593,-0.540754557,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxyzine,DB00557
,118783,DB00682,10029148,57,19402,38,16326,0.302590942,1.262180023,0.822336071,1.957051869,0.468948611,DB0068210029148_,0.757262087,0.232840403,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,warfarin,DB00682
,118784,DB01234,10029148,42,31583,61,32827,0.114109539,0.715650595,0.471097616,1.077983661,0.23230844,DB0123410029148_,1.459689309,-0.334563227,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,dexamethasone,DB01234
,118792,DB01240,10016334,62,5689,17,1559,1,0.999404322,0.57490553,1.829102146,1,DB0124010016334_,0,-0.000595856,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,118793,DB00682,10020642,119,19340,57,16307,0.000348769,1.760280601,1.272357807,2.459835975,0.002287272,DB0068210020642_,6.080395401,0.565473228,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,118794,DB01240,10033775,52,5699,7,1569,0.079464335,2.044948032,0.922862349,5.34776956,0.177535272,DB0124010033775_,1.728585974,0.715372377,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,epoprostenol,DB01240
,118814,DB00758,10027141,30,8270,86,9988,2.09476691757468e-05,0.421333523,0.26807285,0.645896834,0.000207777,DB0075810027141_,8.47904438,-0.864330543,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,118815,DB00264,10046274,47,29560,78,24814,0.000204357,0.505831819,0.344364016,0.735952107,0.001467027,DB0026410046274_,6.524517687,-0.681551039,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,118830,DB00169,10018484,49,38642,26,18149,0.621250273,0.885155968,0.539238865,1.484287758,0.761551285,DB0016910018484_,0.272397762,-0.121991414,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,118832,DB00264,10018484,41,29566,31,24861,0.722946206,1.112080471,0.680379703,1.834805456,0.836991698,DB0026410018484_,0.177941127,0.106232559,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,metoprolol,DB00264
,118833,DB00178,10025482,34,1403,30,1650,0.257576961,1.332725682,0.787086753,2.266983795,0.418443663,DB0017810025482_,0.871213015,0.28722623,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ramipril,DB00178
,118837,DB00788,10037162,80,9276,35,5026,0.327056883,1.238401093,0.821372497,1.901844858,0.495472186,DB0078810037162_,0.702244061,0.213821107,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,118841,DB01267,10061422,29,2823,41,3674,0.808785944,0.920530921,0.550233043,1.521872742,0.896852337,DB0126710061422_,0.108864049,-0.082804687,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,118859,DB00181,10011781,56,9800,16,5855,0.0071011,2.090980618,1.181234581,3.908672628,0.027092301,DB0018110011781_,3.608505699,0.737633151,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,baclofen,DB00181
,118861,DB01068,10021143,55,13708,28,6812,0.90746062,0.976107609,0.607990766,1.599758638,0.958745315,DB0106810021143_,0.042129813,-0.024182444,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,118864,DB01068,10038678,57,13706,6,6834,2.04903509230987e-05,4.737121761,2.045674439,13.45206038,0.000203997,DB0106810038678_,8.49740468,1.555429728,female,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,118877,DB00153,10040979,34,7389,22,3417,0.248845497,0.714694084,0.405373174,1.28481144,0.408270638,DB0015310040979_,0.895824996,-0.335900683,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,118878,DB00404,10040979,48,19844,28,9834,0.541946457,0.849555921,0.521938391,1.407188159,0.697244934,DB0040410040979_,0.360618518,-0.163041512,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,118884,DB01076,10017367,28,25719,34,25549,0.448378838,0.818090578,0.477694902,1.390429202,0.616113637,DB0107610017367_,0.484323857,-0.200782218,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,118886,DB00181,10061822,52,9804,28,5843,0.728758389,1.106830974,0.685384545,1.822333179,0.841866714,DB0018110061822_,0.172133575,0.101500954,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,118893,DB00575,10028372,53,5191,33,3796,0.511391368,1.174419111,0.744799752,1.876525885,0.671726656,DB0057510028372_,0.397903784,0.160773652,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,clonidine,DB00575
,118895,DB00813,10062355,39,10533,28,10140,0.270915915,1.340865096,0.803579156,2.264237427,0.433627137,DB0081310062355_,0.835570247,0.293315,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,118898,DB01175,10016322,189,10535,77,4815,0.424067583,1.121832192,0.854292668,1.485295858,0.592857826,DB0117510016322_,0.522800662,0.114963234,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,118911,DB00950,10012174,56,4662,27,2029,0.718654477,0.902699126,0.558845178,1.491026547,0.833884533,DB0095010012174_,0.181660336,-0.102365975,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,fexofenadine,DB00950
,118942,DB00215,10053762,287,10816,115,5161,0.130137905,1.190802911,0.953346169,1.495428184,0.255904454,DB0021510053762_,1.362951133,0.174627795,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,118946,DB01050,10062244,47,18061,15,9356,0.108343594,1.623109857,0.891170247,3.12697479,0.223550621,DB0105010062244_,1.498117398,0.484343974,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,118961,DB00175,10027599,37,8094,14,6092,0.032508915,1.989057443,1.049181157,3.987179548,0.090212925,DB0017510027599_,2.405582565,0.68766088,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,118964,DB00745,10027599,43,2534,13,1070,0.375793598,1.396630686,0.733474562,2.842953771,0.545595554,DB0074510027599_,0.605877321,0.334062683,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,modafinil,DB00745
,118966,DB00927,10027599,55,7442,12,5004,0.000139359,3.081572033,1.628404432,6.329214731,0.001058994,DB0092710027599_,6.850436349,1.125439867,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,118972,DB00451,10028164,68,47203,14,15405,0.124251911,1.585102468,0.882784099,3.05280158,0.247430697,DB0045110028164_,1.396624747,0.460649054,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,levothyroxine,DB00451
,118980,DB00334,10043071,47,2802,78,2734,0.004862412,0.587999415,0.398848593,0.85873389,0.020009158,DB0033410043071_,3.911565209,-0.531029327,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,olanzapine,DB00334
,119006,DB00264,10050894,38,29569,18,24874,0.044403902,1.775883631,0.988665349,3.306583424,0.114404681,DB0026410050894_,2.168013283,0.574298119,NA,10050894,Anti-neutrophil cytoplasmic antibody positive vasculitis,10021428,Immune system disorders,Immun,metoprolol,DB00264
,119010,DB01275,10050894,175,3804,96,3253,0.000608396,1.558774713,1.202780379,2.029962784,0.00364104,DB0127510050894_,5.615485818,0.443900072,NA,10050894,Anti-neutrophil cytoplasmic antibody positive vasculitis,10021428,Immune system disorders,Immun,hydralazine,DB01275
,119021,DB01275,10068513,44,3935,14,3335,0.000835664,2.663221028,1.429463578,5.271258915,0.004746205,DB0127510068513_,5.350410009,0.979536303,NA,10068513,Pulmonary renal syndrome,10038359,Renal and urinary disorders,Renal,hydralazine,DB01275
,119048,DB00773,10021789,52,2271,48,2779,0.18691455,1.325580973,0.874383867,2.013285692,0.332625771,DB0077310021789_,1.10073723,0.281850834,NA,10021789,Infection,10021881,Infections and infestations,Infec,etoposide,DB00773
,119053,DB00773,10042128,36,2287,56,2771,0.290420854,0.77894374,0.495835646,1.209927402,0.455662398,DB0077310042128_,0.786003099,-0.249816456,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,etoposide,DB00773
,119054,DB00059,10047700,61,766,128,979,0.002466526,0.609231723,0.435005937,0.845928231,0.011543244,DB0005910047700_,4.461654963,-0.495556587,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pegaspargase,DB00059
,119076,DB00422,10028334,57,3378,22,2927,0.000922326,2.244656417,1.347078671,3.866068654,0.005155551,DB0042210028334_,5.26768132,0.808552466,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,methylphenidate,DB00422
,119087,DB00734,10019063,38,4012,69,4833,0.050220043,0.663453859,0.43333447,1.002203934,0.125422604,DB0073410019063_,2.076066408,-0.41029597,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,119092,DB00275,10012378,35,2025,17,1220,0.564081362,1.240266253,0.673080802,2.371669544,0.715945754,DB0027510012378_,0.334150877,0.215326077,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,olmesartan,DB00275
,119103,DB00635,10041349,254,32799,116,23678,3.51603234352958e-05,1.580723592,1.263267871,1.987637752,0.00032605,DB0063510041349_,8.028459407,0.457882712,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,119107,DB01281,10046571,249,8683,8,1790,4.53005148475347e-12,6.415825678,3.197847713,15.05147131,1.84037717583841e-10,DB0128110046571_,22.41588039,1.8587677,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,abatacept,DB01281
,119109,DB01281,10048439,50,8882,6,1792,0.282306223,1.68122645,0.718972123,4.805424453,0.446367357,DB0128110048439_,0.806612995,0.519523557,NA,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,abatacept,DB01281
,119116,DB00476,10022523,44,17213,29,6148,0.01575984,0.541953008,0.331235639,0.899035895,0.051246042,DB0047610022523_,2.971116888,-0.612575983,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,119117,DB00836,10022523,52,5483,87,3988,1.55280099765639e-06,0.434766152,0.301488108,0.621648085,2.12469412927633e-05,DB0083610022523_,10.75929761,-0.832946973,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,loperamide,DB00836
,119136,DB00273,10007515,61,8420,25,2168,0.059651881,0.628288251,0.387498083,1.047174236,0.142820029,DB0027310007515_,1.946169982,-0.464756219,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,topiramate,DB00273
,119163,DB00619,10023232,28,2871,30,2464,0.428609296,0.801057974,0.459749355,1.391771368,0.59717449,DB0061910023232_,0.515545931,-0.221821958,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,imatinib,DB00619
,119164,DB00863,10023232,97,10576,35,5805,0.035275182,1.521157157,1.022318089,2.310882624,0.096006889,DB0086310023232_,2.343335334,0.419471332,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,119171,DB00619,10048959,76,2823,56,2438,0.378630767,1.172021126,0.815286111,1.693534866,0.548654027,DB0061910048959_,0.600287224,0.158729716,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,119182,DB00814,10022052,55,8232,15,3400,0.186776655,1.514408058,0.842099817,2.89039179,0.332455122,DB0081410022052_,1.1012504,0.415024642,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,119183,DB13961,10022052,60,9397,19,6395,0.002672205,2.148957403,1.263307736,3.817076852,0.012303189,DB1396110022052_,4.39789676,0.764982795,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,119184,DB00181,10022061,72,9784,14,5857,2.649404314957e-05,3.07847848,1.719410256,5.916140723,0.000253881,DB0018110022061_,8.278644415,1.124435475,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,119185,DB00335,10022061,65,8401,9,5456,4.62789501661089e-07,4.690049586,2.321969572,10.72298273,7.23211774742076e-06,DB0033510022061_,11.83697865,1.545443155,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,119189,DB13961,10022086,133,9324,54,6360,0.001213688,1.679958199,1.213617162,2.353587298,0.006459666,DB1396110022086_,5.042177622,0.518768911,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,119230,DB00863,10007559,69,10604,55,5785,0.038175963,0.684402817,0.472523175,0.995410152,0.101956432,DB0086310007559_,2.283209698,-0.379208621,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,ranitidine,DB00863
,119232,DB01222,10007559,90,9184,87,5318,0.000935795,0.599068493,0.440231582,0.815462423,0.005214621,DB0122210007559_,5.256288909,-0.512379342,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,budesonide,DB01222
,119234,DB01394,10007559,28,1412,36,1967,0.798546455,1.083464636,0.633622612,1.83556871,0.891223384,DB0139410007559_,0.115160171,0.080163903,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,colchicine,DB01394
,119238,DB13961,10007559,60,9397,64,6350,0.012867918,0.633549415,0.437252314,0.916854215,0.04351386,DB1396110007559_,3.134675769,-0.456417279,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,fish oil,DB13961
,119239,DB14513,10007559,37,7140,36,3528,0.005631624,0.50786092,0.311612267,0.828527925,0.022511935,DB1451310007559_,3.793709672,-0.677547648,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,magnesium,DB14513
,119244,DB00437,10007739,32,6889,36,11510,0.104356122,1.485050603,0.892072816,2.462300329,0.217551704,DB0043710007739_,1.525318736,0.395448848,NA,10007739,Cataract,10015919,Eye disorders,Eye,allopurinol,DB00437
,119247,DB00586,10007739,39,7070,14,2791,0.878774957,1.099695222,0.583049095,2.196337306,0.949052042,DB0058610007739_,0.052291643,0.09503307,NA,10007739,Cataract,10015919,Eye disorders,Eye,diclofenac,DB00586
,119250,DB00863,10007739,52,10621,15,5825,0.028883876,1.901197455,1.052949424,3.639448772,0.082224052,DB0086310007739_,2.498307413,0.642483927,NA,10007739,Cataract,10015919,Eye disorders,Eye,ranitidine,DB00863
,119254,DB01015,10007739,34,9853,30,9351,0.803186936,1.075619689,0.638269573,1.821187131,0.89346856,DB0101510007739_,0.112644132,0.07289695,NA,10007739,Cataract,10015919,Eye disorders,Eye,sulfamethoxazole,DB01015
,119255,DB01068,10007739,48,13715,13,6827,0.055893699,1.837894051,0.979281223,3.700302166,0.135901751,DB0106810007739_,1.995823074,0.608620378,NA,10007739,Cataract,10015919,Eye disorders,Eye,clonazepam,DB01068
,119303,DB00215,10013946,46,11057,20,5256,0.793113948,1.093308261,0.633193066,1.953254339,0.887862015,DB0021510013946_,0.118938937,0.089208201,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,119305,DB00281,10013946,63,11395,9,5662,8.06928695519782e-05,3.477947279,1.718919375,7.961666024,0.000664269,DB0028110013946_,7.316822824,1.246442258,female,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,119308,DB00437,10013946,31,6890,36,11510,0.163726533,1.438441569,0.859603975,2.394454651,0.302386485,DB0043710013946_,1.19604933,0.363560284,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,119313,DB00758,10013946,42,8258,41,10033,0.322343714,1.24455539,0.788993665,1.964496362,0.490674598,DB0075810013946_,0.711974104,0.21877835,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,119315,DB01068,10013946,72,13691,32,6808,0.676503227,1.118825865,0.727330343,1.755791447,0.80384645,DB0106810013946_,0.21834701,0.112279801,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,119316,DB01098,10013946,57,8092,55,7154,0.704084991,0.916237824,0.620469405,1.354036506,0.822564291,DB0109810013946_,0.195328634,-0.087479315,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,119317,DB01222,10013946,55,9219,27,5378,0.493019497,1.188350102,0.735855709,1.961891536,0.655851033,DB0122210013946_,0.4218216,0.172565876,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,119321,DB09140,10013946,59,3682,12,1786,0.004636152,2.384578834,1.264219317,4.886625561,0.019242264,DB0914010013946_,3.95064617,0.869022519,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,oxygen,DB09140
,119355,DB00046,10016322,74,5385,40,4652,0.017973612,1.598103608,1.071247023,2.415161335,0.056796873,DB0004610016322_,2.868274011,0.468817681,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,119356,DB00121,10016322,98,4125,8,460,0.511410371,1.365979654,0.660880681,3.273717429,0.671734833,DB0012110016322_,0.397891611,0.311871867,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,119359,DB00437,10016322,91,6830,106,11440,0.011879089,1.437863529,1.072714751,1.924175617,0.040839953,DB0043710016322_,3.198094441,0.363158351,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,119361,DB00727,10016322,80,3763,46,4127,0.000434177,1.907190186,1.307083127,2.811796778,0.002744672,DB0072710016322_,5.898093814,0.645631052,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,119363,DB00959,10016322,102,7976,39,4963,0.008903028,1.627343382,1.112842465,2.422317423,0.032432415,DB0095910016322_,3.428596908,0.486948858,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,119364,DB01015,10016322,75,9812,49,9332,0.047019616,1.455701441,1.00102008,2.133783431,0.119488515,DB0101510016322_,2.124535017,0.375487875,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,119368,DB09140,10016322,134,3607,35,1763,0.000795683,1.871109722,1.275176278,2.810278044,0.004554063,DB0914010016322_,5.39173548,0.626531689,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,119370,DB14513,10016322,162,7015,43,3521,0.000124193,1.890871153,1.339954024,2.718964197,0.000959979,DB1451310016322_,6.948599555,0.637037651,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,119377,DB00364,10017853,37,2713,14,1386,0.37470162,1.350086418,0.710009049,2.713098718,0.544536523,DB0036410017853_,0.607820262,0.300168604,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,sucralfate,DB00364
,119378,DB00381,10017853,47,29313,28,22859,0.29498225,1.30898351,0.802665243,2.171403323,0.46087621,DB0038110017853_,0.774625798,0.269250889,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,119384,DB00863,10017853,32,10641,18,5822,1,0.972655615,0.529199623,1.842090096,1,DB0086310017853_,0,-0.027725201,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,119396,DB00215,10017885,50,11053,17,5259,0.294236326,1.399403111,0.792481655,2.590830554,0.460056283,DB0021510017885_,0.776406444,0.336045797,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,119398,DB00381,10017885,221,29139,89,22798,5.39579756556864e-08,1.942740237,1.511382594,2.515208291,1.03675832610359e-06,DB0038110017885_,13.77941171,0.66409947,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,119399,DB00437,10017885,46,6875,34,11512,0.000293683,2.265383439,1.421233432,3.643380047,0.001983414,DB0043710017885_,6.222935699,0.817744033,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,119401,DB00758,10017885,50,8250,35,10039,0.011960842,1.738277908,1.105115676,2.761893535,0.041043176,DB0075810017885_,3.193130696,0.552894915,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,119402,DB01015,10017885,38,9849,24,9357,0.127332173,1.504201299,0.878462096,2.623630145,0.251897328,DB0101510017885_,1.378733702,0.408262059,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,119403,DB01222,10017885,74,9200,36,5369,0.427474363,1.199621599,0.793868515,1.842342119,0.59604793,DB0122210017885_,0.517434196,0.182006173,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,119407,DB09140,10017885,63,3678,16,1782,0.02095844,1.907532827,1.084879756,3.548798222,0.064139318,DB0914010017885_,2.746697713,0.645810694,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,oxygen,DB09140
,119410,DB14513,10017885,46,7131,21,3543,0.796019437,1.088315812,0.635294957,1.923114059,0.889513883,DB1451310017885_,0.117080164,0.084631374,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,119436,DB00381,10019022,45,29315,31,22856,0.644447875,1.131746796,0.700341185,1.850763037,0.780476932,DB0038110019022_,0.247850094,0.123762277,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,119469,DB00451,10021027,57,47214,9,15410,0.04410617,2.066973311,1.015668322,4.751011209,0.113782577,DB0045110021027_,2.173465869,0.726085369,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,119524,DB00046,10028334,54,5405,33,4659,0.130909084,1.410462105,0.896443327,2.249709722,0.257055527,DB0004610028334_,1.35846316,0.343917385,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin lispro,DB00046
,119527,DB00364,10028334,45,2705,21,1379,0.794153391,1.092395412,0.634409317,1.938801407,0.888495866,DB0036410028334_,0.118225284,0.08837291,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,sucralfate,DB00364
,119528,DB00581,10028334,25,2088,31,2038,0.420451421,0.787187124,0.443907714,1.382943031,0.589401115,DB0058110028334_,0.528648318,-0.23928929,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,lactulose,DB00581
,119529,DB00688,10028334,37,6453,16,5362,0.027196868,1.921401932,1.041515747,3.70381607,0.078445043,DB0068810028334_,2.545356987,0.653055093,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,mycophenolate mofetil,DB00688
,119533,DB11365,10028334,33,1612,21,1527,0.17087184,1.488379163,0.831658162,2.719922393,0.311987101,DB1136510028334_,1.164793435,0.397687717,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,sennosides,DB11365
,119540,DB01015,10028596,21,9866,50,9331,0.000295739,0.397238541,0.226444906,0.674159332,0.001994226,DB0101510028596_,6.217499277,-0.923218319,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,sulfamethoxazole,DB01015
,119541,DB01068,10028596,57,13706,39,6801,0.12868671,0.725210342,0.473707916,1.120667052,0.253754017,DB0106810028596_,1.371389919,-0.32129354,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,clonazepam,DB01068
,119546,DB14513,10028596,34,7143,30,3534,0.023326931,0.560730467,0.332465392,0.950263519,0.069636386,DB1451310028596_,2.664468056,-0.57851494,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,magnesium,DB14513
,119549,DB00364,10033425,79,2671,24,1376,0.026212972,1.695547845,1.056534433,2.813873902,0.076226127,DB0036410033425_,2.574051003,0.528005901,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sucralfate,DB00364
,119550,DB00688,10033425,65,6425,24,5354,0.000549146,2.256675299,1.39141079,3.775078583,0.003333942,DB0068810033425_,5.703599869,0.813892623,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,mycophenolate mofetil,DB00688
,119554,DB11365,10033425,39,1606,22,1526,0.052931015,1.684145392,0.969006188,2.997125076,0.13053354,DB1136510033425_,2.03612507,0.521258249,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sennosides,DB11365
,119562,DB00381,10033647,32,29328,42,22845,0.026090595,0.593500709,0.362511281,0.963171098,0.075929063,DB0038110033647_,2.577955761,-0.52171687,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,119585,DB06723,10037660,35,995,26,584,0.418177226,0.790233924,0.457045174,1.381997461,0.587189498,DB0672310037660_,0.532407686,-0.235426271,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,aluminum hydroxide,DB06723
,119594,DB00381,10040808,36,29324,36,22851,0.341737992,0.779268551,0.476952927,1.273194208,0.510986419,DB0038110040808_,0.671412266,-0.249399554,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,amlodipine,DB00381
,119596,DB00451,10040808,61,47210,23,15396,0.528395558,0.864944126,0.527391098,1.464849183,0.685783201,DB0045110040808_,0.377193734,-0.145090369,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levothyroxine,DB00451
,119601,DB00695,10040808,28,28021,33,20495,0.069273547,0.620614398,0.361178071,1.059468567,0.160025943,DB0069510040808_,1.832419332,-0.477045327,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,furosemide,DB00695
,119624,DB00338,10042609,146,33528,57,22215,0.000543176,1.697118046,1.240868416,2.348384272,0.003304948,DB0033810042609_,5.712334639,0.528931546,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,omeprazole,DB00338
,119626,DB00381,10042609,85,29275,51,22836,0.142163245,1.300077787,0.907740317,1.878384066,0.27281601,DB0038110042609_,1.298957667,0.262424099,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,amlodipine,DB00381
,119629,DB00586,10042609,45,7064,18,2787,1,0.986340295,0.558516108,1.813740659,1,DB0058610042609_,0,-0.013753857,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,diclofenac,DB00586
,119630,DB00635,10042609,177,32876,62,23732,3.4062697347296e-07,2.060766058,1.534175233,2.799865791,5.47774854557158e-06,DB0063510042609_,12.11481639,0.723077786,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,prednisone,DB00635
,119632,DB00695,10042609,81,27968,37,20491,0.019290866,1.60390998,1.073932148,2.435852757,0.06009605,DB0069510042609_,2.811811171,0.472444386,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,furosemide,DB00695
,119634,DB00758,10042609,22,8278,31,10043,0.678937134,0.86099915,0.474588338,1.53704277,0.805653035,DB0075810042609_,0.216102106,-0.149661762,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,clopidogrel,DB00758
,119635,DB00863,10042609,48,10625,11,5829,0.006158914,2.393832165,1.224736333,5.116425558,0.02416451,DB0086310042609_,3.722870256,0.872895498,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,ranitidine,DB00863
,119640,DB01068,10042609,58,13705,15,6825,0.024312289,1.925520193,1.076151411,3.661113089,0.071981136,DB0106810042609_,2.631351195,0.655196161,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,clonazepam,DB01068
,119642,DB01136,10042609,31,9853,28,11087,0.434493103,1.245785381,0.722451076,2.157163622,0.60302719,DB0113610042609_,0.505792993,0.219766159,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,carvedilol,DB01136
,119643,DB01222,10042609,39,9235,16,5389,0.264118207,1.422348268,0.775858902,2.729095992,0.426015408,DB0122210042609_,0.853279765,0.352309216,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,budesonide,DB01222
,119661,DB00635,10050256,72,32981,20,23774,7.29387682748423e-05,2.594954005,1.562789748,4.498725714,0.000607835,DB0063510050256_,7.405607855,0.953568792,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,119663,DB00695,10050256,53,27996,40,20488,0.916485508,0.969646792,0.630839682,1.501010398,0.962707173,DB0069510050256_,0.038005992,-0.030823406,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,119759,DB00381,10061224,76,29284,50,22837,0.369710849,1.18536111,0.818417026,1.730077511,0.539311264,DB0038110061224_,0.61746239,0.170047463,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,119764,DB00635,10061224,77,32976,29,23765,0.002190787,1.91348736,1.23329393,3.043833588,0.010480082,DB0063510061224_,4.558278802,0.64892742,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,119766,DB00695,10061224,88,27961,47,20481,0.081556114,1.371450487,0.951413848,1.999031238,0.180971885,DB0069510061224_,1.709413589,0.31586893,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,119841,DB00864,10062015,58,6811,60,8332,0.403336715,1.182521937,0.808610702,1.728208286,0.573084234,DB0086410062015_,0.556722569,0.167649392,NA,10062015,Immunosuppressant drug level increased,10022891,Investigations,Inv,tacrolimus,DB00864
,119943,DB00338,10067585,42,33632,24,22248,0.616205626,1.157685333,0.684826278,1.999128345,0.757416114,DB0033810067585_,0.277842489,0.146422609,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,119945,DB00381,10067585,41,29319,30,22857,0.812127042,1.065462325,0.649024005,1.767704106,0.89905753,DB0038110067585_,0.106408254,0.063408813,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,119947,DB00451,10067585,52,47219,15,15404,0.777049522,1.130908399,0.62678114,2.163554566,0.878512755,DB0045110067585_,0.129524852,0.123021202,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,119952,DB00695,10067585,42,28007,33,20495,0.815274309,0.931359838,0.576104856,1.517189448,0.900909559,DB0069510067585_,0.104350405,-0.07110957,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,120045,DB00584,10008190,30,2051,24,1850,0.683136686,1.127459997,0.634650483,2.023179444,0.808421214,DB0058410008190_,0.212672051,0.119967312,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,enalapril,DB00584
,120052,DB00641,10016334,44,14080,18,12457,0.004853469,2.1625466,1.223542676,3.979144934,0.019984871,DB0064110016334_,3.912779741,0.771286509,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,120056,DB00390,10028411,86,4059,25,3276,1.75684599516834e-06,2.775987527,1.756072477,4.53533148,2.36208168710996e-05,DB0039010028411_,10.65338216,1.021006549,female,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,digoxin,DB00390
,120075,DB00331,10042609,73,24873,48,20704,0.234578687,1.26591647,0.867151762,1.862941235,0.391449575,DB0033110042609_,0.937898573,0.235796342,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,metformin,DB00331
,120086,DB01248,10012174,95,2605,54,1320,0.536771366,0.891477828,0.62726483,1.277924742,0.693029219,DB0124810012174_,0.366683118,-0.114874713,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,docetaxel,DB01248
,120111,DB00203,10054997,60,13818,18,8920,0.00344413,2.151710335,1.25223707,3.875700368,0.015127239,DB0020310054997_,4.19125827,0.766263031,NA,10054997,Infusion site infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,120113,DB00682,10054997,58,19401,10,16354,1.13887513365176e-07,4.888852631,2.476422015,10.72943893,2.04267027553984e-06,DB0068210054997_,13.10125265,1.58695764,female,10054997,Infusion site infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,120114,DB00203,10069868,100,13778,29,8909,6.21725952176057e-05,2.229612807,1.460569136,3.500719196,0.000531186,DB0020310069868_,7.540398315,0.801827941,NA,10069868,Device issue,10077536,Product issues,Prod,sildenafil,DB00203
,120121,DB00482,10021097,48,8211,45,3026,1.09128525993646e-05,0.393135553,0.255683645,0.605443614,0.000116936,DB0048210021097_,9.053882657,-0.933600809,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,celecoxib,DB00482
,120129,DB00381,10037400,154,29206,66,22821,2.97382735434169e-05,1.823187558,1.357211922,2.472211666,0.000281683,DB0038110037400_,8.174727983,0.600586375,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,120132,DB01136,10037400,48,9836,55,11060,1,0.981329121,0.651511691,1.473695439,1,DB0113610037400_,0,-0.01884738,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,120133,DB01373,10037400,53,22667,9,7372,0.075559103,1.915114743,0.935939687,4.418698288,0.170722944,DB0137310037400_,1.767713249,0.649777539,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,120142,DB00381,10064911,157,29203,44,22843,1.12578872461546e-10,2.790945633,1.985560574,3.995223864,3.64201312326366e-09,DB0038110064911_,19.43072925,1.026380475,female,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,120145,DB00761,10064911,149,15158,52,8573,0.002419752,1.62056159,1.173038351,2.269812831,0.011363808,DB0076110064911_,4.477321667,0.48277275,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,120153,DB00316,10011985,51,65423,43,36910,0.053532881,0.669169892,0.437063153,1.028698122,0.131622636,DB0031610011985_,2.02781627,-0.401717302,NA,10011985,Decubitus ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,120161,DB00722,10009802,31,25372,31,26001,1,1.024795429,0.602291865,1.743718968,1,DB0072210009802_,0,0.024493011,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,lisinopril,DB00722
,120167,DB00181,10002034,85,9771,52,5819,0.929347509,0.973460904,0.680279701,1.404669644,0.970882903,DB0018110002034_,0.029549412,-0.026897615,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,baclofen,DB00181
,120170,DB00175,10003246,57,8074,23,6083,0.012234219,1.86704755,1.130717426,3.178837621,0.041801176,DB0017510003246_,3.174830798,0.624358333,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,120174,DB01067,10007882,42,4319,32,4791,0.128321489,1.455865355,0.895582154,2.38739583,0.253251518,DB0106710007882_,1.373372141,0.37560047,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,glipizide,DB01067
,120182,DB00338,10021425,38,33636,24,22248,0.897444703,1.047274842,0.611957866,1.825550478,0.956338178,DB0033810021425_,0.044643686,0.046191402,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,omeprazole,DB00338
,120190,DB00115,10042209,99,18326,20,10452,5.11860075884336e-06,2.823075034,1.732157715,4.824464856,6.04820952781288e-05,DB0011510042209_,9.713163183,1.037826728,female,10042209,Stress,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,120192,DB00181,10042209,63,9793,14,5857,0.000341921,2.691203503,1.48987887,5.205527778,0.002249664,DB0018110042209_,6.096974601,0.989988492,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,120222,DB00181,10047340,47,9809,11,5860,0.003879365,2.552436697,1.303503316,5.461888935,0.016636928,DB0018110047340_,4.096130452,0.937048471,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,baclofen,DB00181
,120223,DB00338,10047340,143,33531,51,22221,9.09686524390161e-05,1.858135168,1.340276873,2.612378962,0.000735663,DB0033810047340_,7.214738451,0.619573387,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,omeprazole,DB00338
,120224,DB00641,10047340,49,14075,21,12454,0.005447664,2.064496793,1.214415238,3.626644458,0.021904825,DB0064110047340_,3.82104833,0.724886513,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,simvastatin,DB00641
,120225,DB00682,10047340,60,19399,24,16340,0.001955469,2.105693008,1.291144101,3.53758772,0.009560921,DB0068210047340_,4.650071221,0.744644633,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,warfarin,DB00682
,120226,DB00722,10047340,80,25323,55,25977,0.024745302,1.492090821,1.044917149,2.144212118,0.072938634,DB0072210047340_,2.618136828,0.400178372,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,lisinopril,DB00722
,120230,DB01067,10051055,20,4341,41,4782,0.027940833,0.537397662,0.297790866,0.94021126,0.080098681,DB0106710051055_,2.524495895,-0.621016933,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,glipizide,DB01067
,120277,DB00264,10019851,22,29585,49,24843,0.000104807,0.377020896,0.217033321,0.635642364,0.000830772,DB0026410019851_,7.093154626,-0.975454667,NA,10019851,Hepatotoxicity,10019805,Hepatobiliary disorders,Hepat,metoprolol,DB00264
,120285,DB00264,10040560,40,29567,56,24836,0.013743647,0.600006506,0.389453601,0.916836063,0.045858682,DB0026410040560_,3.082190742,-0.510814781,NA,10040560,Shock,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,120289,DB00047,10043554,35,9250,55,8463,0.014537826,0.582243976,0.36945336,0.906691632,0.048069283,DB0004710043554_,3.035111921,-0.540865716,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,insulin glargine,DB00047
,120292,DB00584,10002034,40,2041,37,1837,0.908852849,0.973025639,0.60360677,1.572195281,0.95913476,DB0058410002034_,0.041723693,-0.027344847,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,enalapril,DB00584
,120293,DB01005,10002034,46,1049,31,836,0.558603436,1.182469595,0.726565588,1.947588712,0.711501044,DB0100510002034_,0.340378394,0.167605128,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,hydroxyurea,DB01005
,120294,DB01005,10013709,36,1059,28,839,1,1.018607898,0.598923978,1.748474688,1,DB0100510013709_,0,0.018436889,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,hydroxyurea,DB01005
,120295,DB00121,10010264,79,4144,13,455,0.214972088,0.667300658,0.365004402,1.318806063,0.367380697,DB0012110010264_,1.001356647,-0.404514574,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,120302,DB00207,10035226,34,9046,34,5421,0.043726494,0.599318267,0.36095754,0.994995888,0.113036083,DB0020710035226_,2.180048192,-0.511962491,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,azithromycin,DB00207
,120305,DB01060,10035226,36,8551,35,5046,0.036686888,0.607017067,0.369908877,0.996924864,0.098944681,DB0106010035226_,2.31319436,-0.499198372,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,amoxicillin,DB01060
,120321,DB00588,10013538,68,16456,18,8450,0.011608265,1.939806883,1.139518319,3.468670952,0.04010558,DB0058810013538_,3.216239792,0.662588423,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,120323,DB00678,10013538,68,15531,14,10710,7.41480120081756e-06,3.349272056,1.864718415,6.451641036,8.34859925309444e-05,DB0067810013538_,9.390831694,1.208743026,female,10013538,Diverticulitis,10021881,Infections and infestations,Infec,losartan,DB00678
,120332,DB01075,10019860,141,19807,22,11075,2.12723118371202e-10,3.583495953,2.274751993,5.90408302,6.5858977224818e-09,DB0107510019860_,18.83833518,1.276338847,female,10019860,Hereditary angioedema,10010331,"Congenital, familial and genetic disorders",Cong,diphenhydramine,DB01075
,120334,DB00668,10020751,139,9952,42,4261,0.049830088,1.417003363,0.994851513,2.055580291,0.124717565,DB0066810020751_,2.081703576,0.348544334,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,epinephrine,DB00668
,120335,DB00761,10020751,129,15178,48,8577,0.014610466,1.518665465,1.081145305,2.164334719,0.048282134,DB0076110020751_,3.030693682,0.417831966,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,potassium chloride,DB00761
,120336,DB01068,10020751,124,13639,39,6801,0.012024545,1.585398168,1.096814474,2.337152685,0.041216036,DB0106810020751_,3.188927865,0.460835586,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,clonazepam,DB01068
,120347,DB00668,10042682,38,10053,13,4290,0.543373893,1.247349655,0.649157459,2.554779014,0.698602694,DB0066810042682_,0.35867309,0.221021024,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,120348,DB00761,10042682,82,15225,23,8602,0.002139371,2.014264043,1.254492451,3.355175367,0.010279382,DB0076110042682_,4.577615123,0.70025389,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,120351,DB00341,10051118,41,11364,20,5048,0.781184599,0.91063896,0.520812351,1.642385668,0.880828655,DB0034110051118_,0.126892162,-0.093608771,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,120355,DB01068,10051118,72,13691,39,6801,0.686369943,0.917082463,0.612044993,1.392625065,0.810800841,DB0106810051118_,0.209732827,-0.086557884,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,120356,DB01075,10051118,38,19910,24,11073,0.690913238,0.880582968,0.514406349,1.53542504,0.813594716,DB0107510051118_,0.206292929,-0.127171127,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,120360,DB06403,10056819,96,21375,20,6641,0.124641764,1.491264959,0.913354961,2.551870843,0.248037912,DB0640310056819_,1.394173674,0.399624726,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,120369,DB01015,10014625,44,9843,57,9324,0.134224696,0.731243027,0.48142544,1.104134985,0.261621455,DB0101510014625_,1.340856648,-0.313009416,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,120374,DB00281,10018100,43,11415,34,5637,0.051265345,0.624546077,0.38858386,1.01106613,0.127381916,DB0028110018100_,2.060565495,-0.47073017,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,120381,DB00683,10027417,13,1571,53,1585,6.97895259563165e-07,0.247582401,0.123291857,0.462601741,1.0428753210698e-05,DB0068310027417_,11.47094383,-1.396011817,male,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,midazolam,DB00683
,120400,DB01275,10070863,50,3929,53,3296,0.273183061,0.791435176,0.525286876,1.190911623,0.436140474,DB0127510070863_,0.829790899,-0.233907303,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,hydralazine,DB01275
,120409,DB00190,10012267,26,3271,77,4597,0.000810282,0.474587983,0.291275861,0.750793646,0.004625533,DB0019010012267_,5.376163565,-0.745308255,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,120428,DB00211,10019063,20,1416,59,1572,8.62534114010984e-05,0.376463011,0.213540267,0.638127549,0.000703217,DB0021110019063_,7.259845341,-0.976935482,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,midodrine,DB00211
,120429,DB08893,10019063,26,2059,59,999,1.57563204380238e-11,0.213925976,0.128607327,0.347169689,5.81270010825903e-10,DB0889310019063_,21.26580573,-1.542125231,male,10019063,Hallucination,10037175,Psychiatric disorders,Psych,mirabegron,DB08893
,120433,DB00190,10028372,30,3267,69,4605,0.024107006,0.612884844,0.384365914,0.956240896,0.071490116,DB0019010028372_,2.638196071,-0.489578217,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,carbidopa,DB00190
,120436,DB00514,10013573,78,2088,32,1504,0.007789133,1.755488618,1.142644684,2.753766649,0.029144107,DB0051410013573_,3.535502564,0.562747233,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,dextromethorphan,DB00514
,120446,DB00514,10041349,34,2132,32,1504,0.258105303,0.749600406,0.44659223,1.260850896,0.419029547,DB0051410041349_,0.869813843,-0.288215006,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,dextromethorphan,DB00514
,120448,DB01136,10069327,34,9850,31,11084,0.455604658,1.23416103,0.735400551,2.07818948,0.623013654,DB0113610069327_,0.473186845,0.210391411,NA,10069327,Product quality issue,10077536,Product issues,Prod,carvedilol,DB01136
,120450,DB00364,10002855,51,2699,25,1375,1,1.039265884,0.628999752,1.758582676,1,DB0036410002855_,0,0.038514583,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,sucralfate,DB00364
,120452,DB01611,10002855,136,11777,16,2345,0.047582199,1.692432614,1.003016898,3.05098299,0.120531789,DB0161110002855_,2.115841753,0.52616691,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,hydroxychloroquine,DB01611
,120465,DB00273,10016825,49,8432,11,2182,0.750820554,1.152714225,0.590128363,2.462615002,0.859159281,DB0027310016825_,0.151800949,0.142119357,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,topiramate,DB00273
,120467,DB00421,10016825,132,8771,28,5224,8.8619708095606e-08,2.807638098,1.853284134,4.392799181,1.62155866849496e-06,DB0042110016825_,13.33212273,1.032343595,female,10016825,Flushing,10047065,Vascular disorders,Vasc,spironolactone,DB00421
,120470,DB00364,10019211,154,2596,34,1366,1.71598029375698e-06,2.382921815,1.624226708,3.585372599,2.31475014441127e-05,DB0036410019211_,10.67362371,0.868327388,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sucralfate,DB00364
,120471,DB00930,10019211,47,1243,10,632,0.009896531,2.388795491,1.181274278,5.338553649,0.035262345,DB0093010019211_,3.344939594,0.87078926,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,colesevelam,DB00930
,120486,DB00490,10047895,74,3996,29,1547,1,0.987869108,0.632181034,1.581152445,1,DB0049010047895_,0,-0.012205072,NA,10047895,Weight decreased,10022891,Investigations,Inv,buspirone,DB00490
,120487,DB00930,10047895,35,1255,21,621,0.475806281,0.824800481,0.462471236,1.504590011,0.641346022,DB0093010047895_,0.444186151,-0.192613763,NA,10047895,Weight decreased,10022891,Investigations,Inv,colesevelam,DB00930
,120488,DB00364,10047899,46,2704,10,1390,0.010229348,2.364231628,1.17232566,5.270896396,0.036210142,DB0036410047899_,3.318416023,0.860453076,NA,10047899,Weight increased,10022891,Investigations,Inv,sucralfate,DB00364
,120489,DB00490,10047899,100,3970,32,1544,0.377591424,1.215312498,0.804995579,1.879046504,0.547600793,DB0049010047899_,0.602208737,0.195001244,NA,10047899,Weight increased,10022891,Investigations,Inv,buspirone,DB00490
,120490,DB01611,10047899,188,11725,17,2344,0.000844357,2.21070676,1.341068282,3.88308123,0.004787819,DB0161110047899_,5.341680261,0.793312265,NA,10047899,Weight increased,10022891,Investigations,Inv,hydroxychloroquine,DB01611
,120491,DB00437,10054112,105,6816,94,11452,1.21046389244993e-05,1.876767346,1.404830094,2.510276789,0.000128398,DB0043710054112_,8.960375146,0.6295508,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,allopurinol,DB00437
,120492,DB00715,10054112,42,4801,11,2276,0.078105414,1.809943991,0.913706817,3.905633223,0.175208092,DB0071510054112_,1.741780915,0.593295901,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,paroxetine,DB00715
,120493,DB00904,10054112,273,22796,151,14305,0.228505887,1.134551456,0.925578544,1.394949858,0.384057627,DB0090410054112_,0.956962667,0.126237379,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,ondansetron,DB00904
,120494,DB00706,10007515,7,1068,84,15841,0.51762739,1.23601472,0.480987022,2.669636593,0.677193636,DB0070610007515_,0.389798026,0.211892268,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,tamsulosin,DB00706
,120500,DB00404,10019196,58,19834,13,9849,0.007616537,2.215421653,1.199044881,4.409625371,0.028636916,DB0040410019196_,3.55305863,0.795442748,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,120503,DB00999,10019196,48,21382,22,12217,0.455976035,1.246651,0.737663459,2.16961786,0.623389239,DB0099910019196_,0.472584173,0.220460756,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,120504,DB01175,10019196,33,10691,18,4874,0.547073479,0.83583808,0.456598747,1.578312229,0.701728792,DB0117510019196_,0.354208286,-0.179320368,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,120508,DB00404,10029148,47,19845,23,9839,1,1.013146779,0.602616769,1.749289885,1,DB0040410029148_,0,0.01306111,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,alprazolam,DB00404
,120509,DB00999,10029148,57,21373,53,12186,0.012700188,0.61322929,0.414087984,0.909380533,0.043068563,DB0099910029148_,3.144961946,-0.489016368,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,hydrochlorothiazide,DB00999
,120510,DB01175,10029148,34,10690,20,4872,0.379153367,0.774764253,0.432865833,1.422082704,0.549169101,DB0117510029148_,0.599348868,-0.255196485,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,escitalopram,DB01175
,120513,DB00811,10020578,23,2775,30,4126,0.674168621,1.139890979,0.630915522,2.034423328,0.80236002,DB0081110020578_,0.22019787,0.130932626,NA,10020578,Hyperbilirubinaemia,10019805,Hepatobiliary disorders,Hepat,ribavirin,DB00811
,120530,DB00005,10019194,206,127876,46,42373,0.015868057,1.483879063,1.073255525,2.090368244,0.051512688,DB0000510019194_,2.965927131,0.394659647,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,120536,DB00051,10028034,68,25663,15,11405,0.011989995,2.014644617,1.139338096,3.796782457,0.041124422,DB0005110028034_,3.191153122,0.700442811,NA,10028034,Mouth ulceration,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,120540,DB00207,10000060,53,9027,21,5434,0.117623406,1.519220582,0.899812099,2.654857821,0.23760615,DB0020710000060_,1.437140808,0.418197428,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,120548,DB00563,10019663,53,46593,41,15307,6.2905374949469e-05,0.42468386,0.277070764,0.655096746,0.000536405,DB0056310019663_,7.530621467,-0.856410245,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,methotrexate,DB00563
,120550,DB00207,10020642,50,9030,25,5430,0.475913816,1.20259992,0.729085188,2.031312785,0.641432955,DB0020710020642_,0.444050613,0.184485813,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,azithromycin,DB00207
,120560,DB01202,10038435,35,6679,25,5693,0.519258701,1.19330477,0.693177053,2.082664306,0.678466717,DB0120210038435_,0.387919855,0.176726576,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,levetiracetam,DB01202
,120610,DB00624,10037660,7,555,56,4340,1,0.977481074,0.373949141,2.163994792,1,DB0062410037660_,0,-0.022776349,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,testosterone,DB00624
,120612,DB01268,10008796,27,2116,33,3097,0.510309218,1.19745116,0.690372555,2.060426039,0.670757734,DB0126810008796_,0.399347259,0.180195264,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,sunitinib,DB01268
,120620,DB00575,10013710,59,5185,87,3742,2.93439817634648e-05,0.489459423,0.344620052,0.691062085,0.000278199,DB0057510013710_,8.187174089,-0.714453715,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,120621,DB00627,10013710,13,1316,38,1561,0.004208836,0.405923084,0.19753499,0.782959303,0.017802983,DB0062710013710_,4.028389262,-0.901591585,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,niacin,DB00627
,120622,DB01275,10013710,33,3946,25,3324,0.791563747,1.111887485,0.639938341,1.954675313,0.887203509,DB0127510013710_,0.119680888,0.106059008,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,120623,DB00169,10024570,90,38601,17,18158,0.000241367,2.490329323,1.471650717,4.463581853,0.00168486,DB0016910024570_,6.386072746,0.91241496,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,120624,DB00338,10024570,52,33622,35,22237,1,0.982619893,0.627800867,1.554684216,1,DB0033810024570_,0,-0.017532914,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,120625,DB00381,10024570,77,29283,52,22835,0.477402487,1.154690358,0.801431713,1.675365939,0.642759952,DB0038110024570_,0.441983949,0.14383222,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,120626,DB00169,10042727,63,38628,21,18154,0.197857456,1.409927381,0.848292606,2.433739053,0.346406382,DB0016910042727_,1.060142678,0.3435382,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,120627,DB01611,10037162,53,11860,14,2347,0.323861239,0.749180257,0.408951713,1.464645821,0.492317016,DB0161110037162_,0.708632429,-0.288775661,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,120632,DB08895,10013710,65,28049,7,6639,0.049518244,2.197790368,1.007690661,5.684872578,0.124078842,DB0889510013710_,2.08683809,0.787452477,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,120643,DB01101,10040844,198,7391,57,3851,5.53331514168612e-05,1.809840499,1.337970643,2.481242444,0.00048152,DB0110110040844_,7.638562292,0.593238719,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,capecitabine,DB01101
,120660,DB00059,10035664,32,795,37,1070,0.538316862,1.163936261,0.695303143,1.939089618,0.694259025,DB0005910035664_,0.364910153,0.15180759,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pegaspargase,DB00059
,120664,DB00531,10054236,41,7211,62,6454,0.009794605,0.591897407,0.388318798,0.893782289,0.03500112,DB0053110054236_,3.352375213,-0.524421958,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,120665,DB00541,10054236,17,3117,38,4259,0.100412331,0.611314371,0.322908597,1.112004395,0.211451539,DB0054110054236_,1.553759436,-0.492143933,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,vincristine,DB00541
,120672,DB00497,10022687,39,19228,33,16342,1,1.004434796,0.615241157,1.648853804,1,DB0049710022687_,0,0.004424991,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,120673,DB00005,10029883,47,128035,10,42409,0.223175348,1.556731371,0.776274421,3.455743744,0.377439457,DB0000510029883_,0.974345103,0.442588348,NA,10029883,Obesity,10027433,Metabolism and nutrition disorders,Metab,etanercept,DB00005
,120678,DB01065,10002034,72,4259,48,3003,0.780196992,1.057643732,0.721614038,1.562170541,0.88036596,DB0106510002034_,0.127417595,0.05604354,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,melatonin,DB01065
,120717,DB00480,10037014,53,67375,35,67627,0.055308618,1.519936524,0.973286277,2.400512404,0.134882127,DB0048010037014_,2.003354014,0.418668573,NA,10037014,Protein total decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,120721,DB00158,10037162,196,16619,85,8019,0.442457326,1.112625354,0.857004081,1.454781156,0.61051423,DB0015810037162_,0.493453677,0.106722407,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,120722,DB00404,10037162,60,19832,8,9854,8.04412509643446e-05,3.726225136,1.773820955,9.027873568,0.000662509,DB0040410037162_,7.319476033,1.315395693,female,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,120737,DB00321,10042464,36,7411,18,2832,0.361359227,0.764283643,0.421995834,1.432151319,0.531226358,DB0032110042464_,0.632567063,-0.268816298,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,amitriptyline,DB00321
,120738,DB00231,10018884,36,3260,28,2111,0.520272332,0.832593653,0.492374336,1.42107402,0.679352123,DB0023110018884_,0.386615695,-0.183209567,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,temazepam,DB00231
,120756,DB00028,10027599,257,13201,39,5576,4.66474014817474e-11,2.783292144,1.978395802,4.01108584,1.60909048287104e-09,DB0002810027599_,20.24759674,1.023634451,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,120758,DB00186,10027599,134,16767,23,9985,6.56909412726167e-10,3.469384582,2.216144988,5.664661976,1.89018762052625e-08,DB0018610027599_,17.78400465,1.243977224,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,120761,DB00213,10027599,149,18746,24,13397,3.09849815393659e-15,4.436657589,2.868358165,7.146251892,1.95778903788998e-13,DB0021310027599_,29.26179041,1.489901298,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,120762,DB00264,10027599,117,29490,30,24862,2.07145419381994e-10,3.287770808,2.185026039,5.090297697,6.43155093413393e-09,DB0026410027599_,18.86205012,1.190209769,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,120768,DB00695,10027599,167,27882,26,20502,7.19874336701557e-18,4.722829076,3.110406396,7.44448841,6.10235516310943e-16,DB0069510027599_,35.0326867,1.552408001,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,120770,DB00761,10027599,85,15222,13,8612,7.1786377439718e-07,3.699039547,2.049987898,7.234992148,1.06725392025056e-05,DB0076110027599_,11.44783655,1.308073204,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,120771,DB00813,10027599,66,10506,8,10160,4.62491524242861e-12,7.977652948,3.818768445,19.24545686,1.87457050342692e-10,DB0081310027599_,22.39747136,2.076644251,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,120810,DB00213,10069327,70,18825,42,13379,0.442405333,1.184480273,0.796132367,1.781487347,0.610467266,DB0021310069327_,0.493530605,0.16930409,NA,10069327,Product quality issue,10077536,Product issues,Prod,pantoprazole,DB00213
,120818,DB00904,10069327,52,23017,15,14441,0.007810158,2.174960284,1.205304096,4.161505737,0.029212379,DB0090410069327_,3.533162721,0.777010404,NA,10069327,Product quality issue,10077536,Product issues,Prod,ondansetron,DB00904
,120829,DB00586,10013710,35,7074,23,2782,0.058118101,0.598490249,0.343082789,1.062959172,0.139906061,DB0058610013710_,1.966784072,-0.513345047,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,120850,DB00683,10041962,27,1557,42,1596,0.113028073,0.659046986,0.38866435,1.100359301,0.230591656,DB0068310041962_,1.467106856,-0.416960448,NA,10041962,Status epilepticus,10029205,Nervous system disorders,Nerv,midazolam,DB00683
,120858,DB00951,10072268,34,618,19,546,0.123024706,1.580406119,0.864620512,2.969601712,0.245768908,DB0095110072268_,1.403363585,0.457681852,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,isoniazid,DB00951
,120859,DB00028,10059830,38,13420,22,5593,0.255663113,0.719879145,0.414609269,1.279086523,0.416402077,DB0002810059830_,0.876103954,-0.328671935,NA,10059830,Infusion site rash,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,120860,DB00646,10013710,47,3406,22,1978,0.452072424,1.240656858,0.730433509,2.168530706,0.619650283,DB0064610013710_,0.478600019,0.215640964,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,120861,DB00927,10013710,43,7454,42,4974,0.095179265,0.683218481,0.435322762,1.072920175,0.203480031,DB0092710013710_,1.592187406,-0.380940586,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,120862,DB00370,10013950,33,4508,26,3637,1,1.023999557,0.592780911,1.786259312,1,DB0037010013950_,0,0.023716094,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,mirtazapine,DB00370
,120867,DB00927,10062237,36,7461,33,4983,0.217862166,0.728621111,0.44091412,1.207605148,0.371055986,DB0092710062237_,0.991402322,-0.31660142,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,famotidine,DB00927
,120878,DB00281,10027496,19,11439,38,5633,2.63664974872581e-07,0.246242431,0.13396107,0.438356741,4.34918974868265e-06,DB0028110027496_,12.34552099,-1.401438736,male,10027496,Methaemoglobinaemia,10005329,Blood and lymphatic system disorders,Blood,lidocaine,DB00281
,120897,DB00193,10048393,117,19203,25,8677,0.000357187,2.114640025,1.362873238,3.402774454,0.002332008,DB0019310048393_,6.061025756,0.748884597,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,120904,DB00641,10073085,20,14104,31,12444,0.049872041,0.569245664,0.307325792,1.0315947,0.124780981,DB0064110073085_,2.081195232,-0.563443191,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,120905,DB00722,10073085,31,25372,32,26000,1,0.992727963,0.585666593,1.680536377,1,DB0072210073085_,0,-0.007298607,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,120918,DB01129,10016256,58,854,22,414,0.389126475,1.277860957,0.757922133,2.224346863,0.55902437,DB0112910016256_,0.58156221,0.245187553,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,rabeprazole,DB01129
,120923,DB00273,10003553,50,8431,8,2185,0.253719552,1.619682315,0.7604157,3.962314164,0.414237611,DB0027310003553_,0.88131553,0.482230028,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,topiramate,DB00273
,120933,DB00047,10005554,100,9185,91,8427,1,1.008213304,0.750123223,1.356559374,1,DB0004710005554_,0,0.008179758,NA,10005554,Blood glucose abnormal,10022891,Investigations,Inv,insulin glargine,DB00047
,120938,DB00273,10016173,235,8246,50,2143,0.234154671,1.221427998,0.893155017,1.69888182,0.391032301,DB0027310016173_,0.938965112,0.200020664,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,topiramate,DB00273
,120939,DB00046,10033557,41,5418,14,4678,0.001728722,2.528273363,1.348156152,5.027981636,0.008620653,DB0004610033557_,4.753594496,0.927536605,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,insulin lispro,DB00046
,120946,DB01012,10023547,1568,9064,1535,7150,3.85954875009361e-08,0.805807911,0.745614444,0.870868745,7.62482066112067e-07,DB0101210023547_,14.08668685,-0.215909889,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,cinacalcet,DB01012
,120947,DB01012,10050196,26,10606,35,8650,0.053800032,0.605880955,0.349939504,1.036630458,0.132137342,DB0101210050196_,2.023913425,-0.501071756,NA,10050196,Blood phosphorus increased,10022891,Investigations,Inv,cinacalcet,DB01012
,120956,DB08816,10028596,77,1074,133,1769,0.768422607,0.95360198,0.703245732,1.285924766,0.873007498,DB0881610028596_,0.135811134,-0.047508907,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,ticagrelor,DB08816
,120962,DB00863,10019860,68,10605,8,5832,1.43180678269147e-06,4.673614551,2.240501422,11.26755493,1.97663031948767e-05,DB0086310019860_,10.83153193,1.541932766,female,10019860,Hereditary angioedema,10010331,"Congenital, familial and genetic disorders",Cong,ranitidine,DB00863
,120963,DB09153,10019860,179,7620,43,5656,4.1296714872933e-13,3.089572096,2.199804998,4.424730583,1.94531209755384e-11,DB0915310019860_,24.6630136,1.128032601,female,10019860,Hereditary angioedema,10010331,"Congenital, familial and genetic disorders",Cong,sodium chloride,DB09153
,120965,DB01075,10034829,53,19895,15,11082,0.021835195,1.968112808,1.092338529,3.761098824,0.066244009,DB0107510034829_,2.714410248,0.677075118,NA,10034829,Pharyngeal oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,120991,DB00635,10023469,75,32978,22,23772,0.000114062,2.45736315,1.510300082,4.153410767,0.000893096,DB0063510023469_,7.02081638,0.899088885,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,prednisone,DB00635
,120992,DB00563,10048592,115,46531,32,15316,0.444617691,1.182900933,0.793142595,1.810194081,0.612679532,DB0056310048592_,0.489913266,0.167969839,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,120993,DB00635,10048592,78,32975,30,23764,0.003222719,1.873705983,1.214955734,2.958931411,0.014340471,DB0063510048592_,4.24466957,0.627918279,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,120994,DB00563,10055798,61,46585,36,15312,0.006558867,0.556959993,0.362866166,0.866129592,0.025423951,DB0056310055798_,3.672063582,-0.585261867,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,methotrexate,DB00563
,120996,DB00537,10030095,37,7520,19,4279,0.781624682,1.108088074,0.620198466,2.042589062,0.881110577,DB0053710030095_,0.126572148,0.102636075,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,121002,DB01068,10013663,48,13715,34,6806,0.126268814,0.700572444,0.44172918,1.122268027,0.250489433,DB0106810013663_,1.384338543,-0.355857501,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,121005,DB08895,10046735,180,27934,18,6628,0.000127996,2.372722185,1.457767929,4.097828582,0.000984459,DB0889510046735_,6.923418552,0.864037897,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,121011,DB00829,10020751,101,7951,24,4430,7.03048976075126e-05,2.344586115,1.487917433,3.833144639,0.000588805,DB0082910020751_,7.437415639,0.852108889,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,diazepam,DB00829
,121014,DB00959,10040753,129,7949,43,4959,0.000261667,1.871470657,1.313184919,2.713396872,0.001803863,DB0095910040753_,6.317824837,0.626724569,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,121027,DB01224,10011906,434,7674,372,5545,0.020609846,0.843012105,0.729076634,0.97509129,0.063285358,DB0122410011906_,2.760101287,-0.170773961,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,121038,DB06643,10031252,69,52352,21,7494,0.003876726,0.470343902,0.284891674,0.807801533,0.016628548,DB0664310031252_,4.096634318,-0.754291146,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,denosumab,DB06643
,121047,DB00335,10023232,82,8384,29,5436,0.004484669,1.833266815,1.185425381,2.908980653,0.01872441,DB0033510023232_,3.977927255,0.60609952,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,121050,DB00563,10030095,93,46553,29,15319,0.916370434,1.055254846,0.688717,1.661945198,0.962639876,DB0056310030095_,0.038075898,0.053782298,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,121052,DB00758,10030095,68,8232,58,10016,0.048406956,1.426451274,0.988766584,2.06378656,0.122098431,DB0075810030095_,2.102927751,0.355189734,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,121054,DB08895,10030095,55,28059,11,6635,0.753967721,1.182323735,0.611669318,2.506532828,0.861653981,DB0889510030095_,0.148901503,0.167481769,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,121058,DB01050,10013538,41,18067,23,9348,0.792120969,0.922339378,0.540250403,1.611221066,0.88743507,DB0105010013538_,0.119419921,-0.080842034,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,121060,DB06273,10013538,53,5042,17,1393,0.562097654,0.861338219,0.489077982,1.592221224,0.714393871,DB0627310013538_,0.336320829,-0.149268031,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,tocilizumab,DB06273
,121061,DB01104,10003239,353,15110,89,7197,2.24780491540194e-08,1.889125946,1.490538881,2.415472091,4.65591427906541e-07,DB0110410003239_,14.57995735,0.63611426,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,121062,DB00741,10008479,69,4025,37,3137,0.07555476,1.45336151,0.958312602,2.235755852,0.170722944,DB0074110008479_,1.767713249,0.373879156,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,121075,DB00741,10020642,32,4062,25,3149,1,0.992299586,0.568441813,1.750353772,1,DB0074110020642_,0,-0.007730216,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocortisone,DB00741
,121076,DB01050,10020642,124,17984,84,9287,0.056553471,0.76234245,0.572571014,1.019147414,0.137043237,DB0105010020642_,1.987458805,-0.271359415,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,121077,DB01104,10020642,122,15341,50,7236,0.460382501,1.150876804,0.820634164,1.635219634,0.627799748,DB0110410020642_,0.465534035,0.14052409,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,sertraline,DB01104
,121083,DB00624,10022437,8,554,62,4334,1,1.009431486,0.41517518,2.130049106,1,DB0062410022437_,0,0.009387287,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,testosterone,DB00624
,121090,DB00624,10033371,22,540,108,4288,0.048953313,1.617363887,0.964740175,2.602323429,0.123032733,DB0062410033371_,2.095304833,0.480797594,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,testosterone,DB00624
,121105,DB00635,10029350,33,33020,75,23719,1.11624084145515e-08,0.316067798,0.203153033,0.482177998,2.48647377268209e-07,DB0063510029350_,15.2072301,-1.151798537,male,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,121106,DB00864,10029350,31,6838,67,8325,0.007904853,0.563324527,0.355172778,0.875758881,0.029497312,DB0086410029350_,3.523456129,-0.573899392,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,tacrolimus,DB00864
,121118,DB00787,10013911,100,16900,92,17156,0.515316267,1.10341215,0.822259559,1.482107028,0.675145805,DB0078710013911_,0.392826603,0.098407333,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,121131,DB06643,10028596,75,52346,23,7492,0.00312473,0.466716985,0.289012551,0.780992129,0.01398851,DB0664310028596_,4.269518967,-0.762032232,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,denosumab,DB06643
,121133,DB08895,10043521,67,28047,7,6639,0.037021298,2.265638843,1.040490033,5.85449911,0.099637007,DB0889510043521_,2.306221626,0.817856769,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,121135,DB09053,10021789,15,2270,43,4009,0.130058751,0.616117913,0.317193927,1.134294411,0.255806215,DB0905310021789_,1.363335092,-0.484316917,NA,10021789,Infection,10021881,Infections and infestations,Infec,ibrutinib,DB09053
,121140,DB00921,10016256,124,5721,100,4803,0.786598846,1.041031791,0.791121156,1.372668511,0.884240379,DB0092110016256_,0.123026331,0.040212328,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,121154,DB00046,10016807,26,5433,33,4659,0.150079031,0.675668202,0.387460619,1.166752681,0.284055973,DB0004610016807_,1.258583974,-0.392053149,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,insulin lispro,DB00046
,121155,DB00046,10038435,58,5401,71,4621,0.05023306,0.698957454,0.484235621,1.005327899,0.125427566,DB0004610038435_,2.076026853,-0.358165406,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,insulin lispro,DB00046
,121159,DB00620,10006784,36,4792,19,3113,0.492204046,1.230813803,0.68610322,2.27601845,0.655117267,DB0062010006784_,0.422941025,0.207675579,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,triamcinolone,DB00620
,121170,DB00741,10033425,93,4001,45,3129,0.009124344,1.616140407,1.116694274,2.36882672,0.033085695,DB0074110033425_,3.40865426,0.480040842,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocortisone,DB00741
,121187,DB00737,10008190,41,2760,13,919,1,1.050098046,0.548677143,2.145819461,1,DB0073710008190_,0,0.048883537,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,meclizine,DB00737
,121197,DB00544,10028116,51,2384,59,2594,0.77296734,0.940541477,0.630901779,1.398077707,0.875860279,DB0054410028116_,0.132548699,-0.061299531,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,fluorouracil,DB00544
,121198,DB09053,10029354,27,2258,59,3993,0.428840597,0.809258287,0.491814245,1.300891281,0.597354271,DB0905310029354_,0.515244923,-0.211637146,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,ibrutinib,DB09053
,121199,DB00544,10043554,69,2366,104,2549,0.036373513,0.714826483,0.516683366,0.983808497,0.098301233,DB0054410043554_,2.319718712,-0.335715447,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,fluorouracil,DB00544
,121201,DB00814,10013710,62,8225,46,3369,0.002810065,0.552131128,0.370139516,0.828759141,0.012812241,DB0081410013710_,4.357354224,-0.593969709,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,121203,DB00814,10038435,60,8227,34,3381,0.139331312,0.725248891,0.467511509,1.141708243,0.268922682,DB0081410038435_,1.313331369,-0.321240386,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,meloxicam,DB00814
,121204,DB00814,10070863,103,8184,86,3329,2.23372043305215e-06,0.487195812,0.361238303,0.658416996,2.92251575822677e-05,DB0081410070863_,10.44048066,-0.71908916,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,meloxicam,DB00814
,121206,DB00950,10006451,111,4607,26,2030,0.003434978,1.881014337,1.213919878,3.014624831,0.015096247,DB0095010006451_,4.19330909,0.631811172,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,fexofenadine,DB00950
,121229,DB01050,10036018,52,18056,32,9339,0.489250551,0.840505388,0.530562245,1.350312503,0.65261027,DB0105010036018_,0.426775158,-0.173751916,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,ibuprofen,DB01050
,121230,DB00196,10037377,32,5051,24,3261,0.585302541,0.860839155,0.490340087,1.530300908,0.732830509,DB0019610037377_,0.310840833,-0.149847604,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluconazole,DB00196
,121234,DB00471,10037400,53,14136,13,5452,0.168527236,1.572423708,0.8447394,3.146810382,0.308967723,DB0047110037400_,1.174518462,0.452618192,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,121238,DB00281,10005191,30,11428,21,5650,0.234275736,0.706278478,0.390740683,1.299175074,0.391141596,DB0028110005191_,0.938685647,-0.347745675,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,lidocaine,DB00281
,121245,DB01076,10016334,68,25679,39,25544,0.006491386,1.734394575,1.152764158,2.642318553,0.025214433,DB0107610016334_,3.6803387,0.550658404,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,121247,DB01076,10024570,38,25709,32,25551,0.550282596,1.180196894,0.717722544,1.95208396,0.704614346,DB0107610024570_,0.350104653,0.165681284,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,121248,DB00281,10042682,40,11418,11,5660,0.100126746,1.80252084,0.906866234,3.898344896,0.210968458,DB0028110042682_,1.556046645,0.589186152,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,121249,DB00331,10042682,102,24844,37,20715,7.20089812532673e-06,2.298495132,1.563000371,3.447109049,8.14263743704939e-05,DB0033110042682_,9.415811328,0.832254619,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,121269,DB00916,10015150,49,5274,13,2418,0.098001386,1.727991372,0.921035067,3.478785461,0.207881729,DB0091610015150_,1.570785972,0.546959677,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,metronidazole,DB00916
,121274,DB00203,10007598,47,13831,14,8924,0.008535913,2.166013205,1.171541886,4.262683582,0.031368956,DB0020310007598_,3.461936526,0.772888245,NA,10007598,Cardiac pacemaker insertion,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,121283,DB00695,10007598,51,27998,21,20507,0.030900483,1.778767863,1.050722455,3.114550893,0.086706079,DB0069510007598_,2.445231286,0.575920913,NA,10007598,Cardiac pacemaker insertion,10042613,Surgical and medical procedures,Surg,furosemide,DB00695
,121300,DB00047,10016807,56,9229,50,8468,0.922517328,1.027650581,0.688354392,1.537873004,0.965974225,DB0004710016807_,0.034618127,0.027275207,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,insulin glargine,DB00047
,121301,DB00688,10016807,35,6455,16,5362,0.04864841,1.816992506,0.978266414,3.519958547,0.122541778,DB0068810016807_,2.099303259,0.597182665,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,mycophenolate mofetil,DB00688
,121302,DB00688,10030124,58,6432,41,5337,0.478405188,1.173786983,0.772057951,1.799151528,0.643710283,DB0068810030124_,0.440506526,0.16023526,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,121304,DB00635,10039163,57,32996,26,23768,0.058080349,1.57916936,0.976492674,2.61756506,0.13983738,DB0063510039163_,1.967275103,0.456898987,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,prednisone,DB00635
,121307,DB00996,10039163,49,38904,16,22409,0.05262803,1.764006967,0.985849257,3.324059099,0.129965158,DB0099610039163_,2.040488877,0.567587907,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,gabapentin,DB00996
,121367,DB00641,10046274,32,14092,46,12429,0.040206018,0.613575657,0.377911569,0.985207134,0.106073992,DB0064110046274_,2.243618394,-0.488451702,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,121379,DB01067,10030095,39,4322,31,4792,0.186627125,1.394814294,0.846405445,2.316442128,0.33227175,DB0106710030095_,1.10180212,0.332761284,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,121381,DB00047,10055798,31,9254,41,8477,0.125885699,0.692631856,0.419547952,1.132902926,0.24988903,DB0004710055798_,1.386738339,-0.367256654,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,insulin glargine,DB00047
,121388,DB00635,10061024,107,32946,108,23686,0.015159054,0.712292869,0.539775482,0.939885602,0.049729264,DB0063510061024_,3.001161712,-0.33926612,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,prednisone,DB00635
,121391,DB00433,10006451,57,7599,31,5989,0.106188769,1.449101818,0.918595017,2.325501025,0.220487917,DB0043310006451_,1.511912384,0.370943928,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,121392,DB00904,10006451,247,22822,85,14371,7.2149906345374e-07,1.829801812,1.423268512,2.371953242,1.07205216975023e-05,DB0090410006451_,11.44335074,0.604207662,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,121394,DB00924,10006451,162,10000,27,4224,1.13580855768812e-06,2.534267414,1.675823392,3.970005708,1.6020782365888e-05,DB0092410006451_,11.04162378,0.929904607,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,cyclobenzaprine,DB00924
,121395,DB01060,10006451,149,8438,46,5035,5.1500145765133e-05,1.932719374,1.377340517,2.757274239,0.000452963,DB0106010006451_,7.699699075,0.658928013,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,121397,DB00338,10013082,78,33596,34,22238,0.042490557,1.518519619,1.002474938,2.344422106,0.110679247,DB0033810013082_,2.201118929,0.417735926,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,121400,DB00480,10013082,48,67380,43,67619,0.601709051,1.120237114,0.72661239,1.731928431,0.745963701,DB0048010013082_,0.293078338,0.113540372,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,121406,DB01234,10013082,52,31573,33,32855,0.029435618,1.639715929,1.039818775,2.61951711,0.08345967,DB0123410013082_,2.483391759,0.494523013,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,121407,DB01211,10035664,35,1617,33,754,0.005353264,0.494697412,0.296070276,0.828297348,0.021601252,DB0121110035664_,3.835004008,-0.703808992,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,clarithromycin,DB01211
,121408,DB00787,10048959,350,16650,233,17015,4.00010316523919e-07,1.535046932,1.295031866,1.822224076,6.32546636212743e-06,DB0078710048959_,11.97092679,0.428560955,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,121410,DB00327,10051055,64,6074,46,4216,0.846255703,0.965696449,0.649488505,1.445860023,0.922769955,DB0032710051055_,0.080375312,-0.034905729,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,hydromorphone,DB00327
,121411,DB00433,10051055,86,7570,93,5927,0.033768635,0.724051884,0.532580621,0.983430593,0.092914118,DB0043310051055_,2.376079676,-0.322892226,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,prochlorperazine,DB00433
,121412,DB01060,10051055,39,8548,41,5040,0.010526532,0.560900337,0.351837393,0.892813965,0.037087313,DB0106010051055_,3.294480334,-0.578212041,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,amoxicillin,DB01060
,121425,DB00381,10028735,233,29127,75,22812,1.6232860200727e-12,2.433028983,1.866841163,3.201863693,7.0467502952289e-11,DB0038110028735_,23.37586946,0.889136976,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,121426,DB00169,10041232,59,38632,22,18153,0.404652613,1.26013605,0.760389291,2.160548991,0.574391464,DB0016910041232_,0.554444123,0.231219691,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,121428,DB00264,10041232,48,29559,23,24869,0.031171209,1.755805808,1.046984718,3.025545986,0.087280354,DB0026410041232_,2.438629882,0.562927901,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,121429,DB00381,10041232,50,29310,18,22869,0.004554528,2.167289446,1.242212513,3.948543575,0.018951413,DB0038110041232_,3.965876777,0.773477283,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,121434,DB00641,10047924,44,14080,33,12442,0.494828044,1.178211727,0.732790993,1.911243387,0.657228907,DB0064110047924_,0.419722909,0.163997804,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,121441,DB06228,10068319,51,15861,32,16044,0.036518279,1.612104438,1.015730402,2.593716903,0.098611359,DB0622810068319_,2.316568825,0.47754043,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,121460,DB00005,10028347,85,127997,23,42396,0.43668523,1.22409053,0.764654107,2.034185708,0.605245691,DB0000510028347_,0.502120802,0.202198144,NA,10028347,Muscle twitching,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,121466,DB00476,10022998,1217,16040,442,5735,0.794758103,0.984458709,0.878437414,1.104752686,0.88886159,DB0047610022998_,0.117813747,-0.015663322,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,121468,DB00028,10016825,92,13366,38,5577,1,1.010192975,0.684221008,1.51768887,1,DB0002810016825_,0,0.010141377,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,human immunoglobulin g,DB00028
,121474,DB00099,10013709,56,2329,53,1902,0.495163454,0.862916705,0.578980086,1.287507059,0.657505187,DB0009910013709_,0.419302626,-0.14743711,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,filgrastim,DB00099
,121478,DB01195,10007515,53,1186,45,699,0.086855541,0.694310224,0.452439837,1.069308275,0.189814832,DB0119510007515_,1.661706251,-0.36483641,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,flecainide,DB01195
,121485,DB00193,10069327,66,19254,19,8683,0.099557594,1.566508706,0.928070658,2.765828478,0.210122961,DB0019310069327_,1.56006239,0.448849389,NA,10069327,Product quality issue,10077536,Product issues,Prod,tramadol,DB00193
,121496,DB01202,10067482,92,6622,67,5651,0.337590256,1.171772847,0.844254555,1.633534378,0.506785452,DB0120210067482_,0.679667536,0.158517856,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,121499,DB01067,10028810,56,4305,37,4786,0.016010854,1.68250787,1.088797449,2.627273571,0.051854643,DB0106710028810_,2.959310805,0.52028546,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,glipizide,DB01067
,121500,DB00264,10062244,70,29537,37,24855,0.025042207,1.591984952,1.053752826,2.440442752,0.073541965,DB0026410062244_,2.609899087,0.464981635,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,121501,DB00331,10062244,64,24882,28,20724,0.004412364,1.903700089,1.202821588,3.084615859,0.018485718,DB0033110062244_,3.99075682,0.643799407,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,121505,DB13961,10062244,48,9409,12,6402,0.000914964,2.721465947,1.422698399,5.633337599,0.005121344,DB1396110062244_,5.274338372,1.001170686,female,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,121523,DB01222,10009887,33,9241,33,5372,0.029581877,0.581372695,0.347336415,0.973009808,0.083797785,DB0122210009887_,2.479348702,-0.542363256,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,121524,DB01373,10009887,61,22659,23,7358,0.526997059,0.861262008,0.524899048,1.459180818,0.684700245,DB0137310009887_,0.378774135,-0.149356514,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,121526,DB00003,10011906,58,2940,71,2522,0.049434181,0.70080802,0.484568548,1.010003621,0.12396274,DB0000310011906_,2.087774241,-0.355521295,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dornase alfa,DB00003
,121527,DB00030,10047571,24,2182,31,1790,0.102522407,0.635188957,0.355323684,1.122696469,0.214802237,DB0003010047571_,1.538037503,-0.453832754,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,insulin human,DB00030
,121534,DB00051,10021519,73,25658,28,11392,0.589435295,1.157543991,0.738964569,1.86041839,0.736206692,DB0005110021519_,0.306244368,0.146300512,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,121539,DB00338,10037162,143,33531,50,22222,6.27627337437647e-05,1.89538216,1.36398159,2.672051657,0.000535362,DB0033810037162_,7.53256713,0.639420486,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,121541,DB00005,10064385,169,127913,72,42347,0.073865577,0.777074958,0.586259937,1.038942307,0.167961997,DB0000510064385_,1.784017536,-0.252218462,NA,10064385,Circumstance or information capable of leading to medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,121553,DB00338,10023424,74,33600,12,22260,2.12421499664413e-07,4.085320014,2.20398606,8.262101537,3.58146191063445e-06,DB0033810023424_,12.53973949,1.407400064,female,10023424,Kidney infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,121555,DB00404,10054236,43,19849,19,9843,0.787326985,1.122276536,0.639788962,2.040341263,0.884765643,DB0040410054236_,0.122432479,0.115359243,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,alprazolam,DB00404
,121557,DB00231,10013710,37,3259,15,2124,0.153085155,1.607476125,0.858669975,3.160937913,0.288323537,DB0023110013710_,1.243672036,0.474665325,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,121558,DB00761,10013710,77,15230,35,8590,0.3243294,1.240870533,0.821151598,1.908671944,0.49278871,DB0076110013710_,0.707674777,0.215813176,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,121559,DB00956,10013710,51,5763,23,3444,0.27996598,1.325086311,0.793592866,2.275958757,0.443815558,DB0095610013710_,0.812346212,0.281477598,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,121570,DB00668,10003239,117,9974,39,4264,0.188194217,1.282482672,0.883965893,1.896645566,0.334303236,DB0066810003239_,1.095706806,0.248797787,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,epinephrine,DB00668
,121571,DB00959,10003239,225,7853,103,4899,0.009602743,1.362721338,1.071451728,1.742711592,0.034474916,DB0095910003239_,3.367523285,0.309483684,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,methylprednisolone,DB00959
,121572,DB09153,10003239,99,7700,32,5667,2.47686881934957e-05,2.276768877,1.512114355,3.511692444,0.000239663,DB0915310003239_,8.336276128,0.822757279,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium chloride,DB09153
,121573,DB00281,10033775,91,11367,30,5641,0.052671676,1.505291931,0.98526564,2.359408782,0.13004039,DB0028110033775_,2.039910185,0.408986853,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,121574,DB00697,10033775,113,5983,19,1787,0.020920448,1.77618339,1.082753307,3.068448763,0.064049151,DB0069710033775_,2.748104509,0.5744669,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,121575,DB00904,10033775,231,22838,102,14354,0.002707777,1.423385825,1.121650537,1.816837721,0.01243321,DB0090410033775_,4.387384161,0.353038417,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,121579,DB00065,10021097,49,9415,40,4917,0.043289233,0.639757696,0.412107452,0.998489146,0.112241199,DB0006510021097_,2.18710516,-0.446665774,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,infliximab,DB00065
,121581,DB00065,10043071,28,9436,30,4927,0.007895804,0.487353406,0.280218238,0.845212735,0.02946982,DB0006510043071_,3.524388574,-0.71876574,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,infliximab,DB00065
,121583,DB00582,10011906,43,1087,81,1493,0.112967013,0.72922826,0.487472943,1.078019022,0.230529711,DB0058210011906_,1.467375527,-0.315768482,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,voriconazole,DB00582
,121584,DB00879,10011906,23,1754,76,3636,0.051261824,0.627396767,0.374085034,1.01565655,0.127379187,DB0087910011906_,2.06058692,-0.466176136,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,emtricitabine,DB00879
,121586,DB08877,10016766,46,3243,39,3190,0.514195801,1.160183584,0.738501165,1.830869782,0.674197467,DB0887710016766_,0.394232233,0.148578255,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,ruxolitinib,DB08877
,121594,DB00916,10030124,34,5289,23,2408,0.152406339,0.673059722,0.384123354,1.199454957,0.287312674,DB0091610030124_,1.2471842,-0.395921214,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,121595,DB00950,10030124,52,4666,24,2032,0.802804781,0.943572601,0.56949276,1.605232647,0.893313651,DB0095010030124_,0.112817527,-0.058081969,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,121606,DB00338,10029151,38,33636,18,22254,0.275630462,1.396729119,0.777588808,2.600600853,0.438888185,DB0033810029151_,0.823510603,0.33413316,NA,10029151,Nephropathy,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,121620,DB01104,10000125,35,15428,15,7271,0.879644189,1.099660075,0.584791597,2.168600235,0.949457398,DB0110410000125_,0.051864617,0.095001109,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,121621,DB00715,10020642,58,4785,31,2256,0.569351307,0.882133715,0.559134416,1.41599037,0.720261201,DB0071510020642_,0.328141353,-0.125411631,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,paroxetine,DB00715
,121623,DB00213,10047924,67,18828,30,13391,0.038610878,1.588384604,1.017615722,2.532833405,0.102846265,DB0021310047924_,2.274519982,0.462717528,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,121631,DB00404,10016334,62,19830,14,9848,0.006810321,2.199272178,1.216774078,4.256343719,0.026220782,DB0040410016334_,3.641202979,0.788126477,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,121653,DB00451,10053156,77,47194,13,15406,0.026752603,1.933410425,1.06626013,3.795928452,0.0774526,DB0045110053156_,2.558089139,0.659285503,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,121655,DB00996,10053156,62,38891,23,22402,0.071949194,1.552739007,0.94809056,2.626899651,0.164694207,DB0099610053156_,1.803664816,0.440020472,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,121667,DB00973,10010774,69,3782,63,2958,0.377771291,0.856635663,0.597730211,1.22954845,0.547720732,DB0097310010774_,0.601989736,-0.154742582,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ezetimibe,DB00973
,121670,DB09401,10016256,44,716,35,725,0.355346064,1.27273964,0.787641624,2.070220088,0.525103094,DB0940110016256_,0.644160666,0.241171774,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,isosorbide,DB09401
,121672,DB00996,10016454,63,38890,26,22399,0.185799436,1.395582722,0.870594086,2.29713424,0.331201938,DB0099610016454_,1.105027004,0.33331205,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,121674,DB06643,10016454,184,52237,15,7500,0.031573855,1.761188223,1.03959071,3.212874711,0.088176666,DB0664310016454_,2.428412913,0.565988708,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,121676,DB00973,10017577,67,3784,36,2985,0.071569836,1.468051317,0.96201103,2.27328585,0.16399731,DB0097310017577_,1.807905252,0.383935887,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,121678,DB09401,10019211,34,726,16,744,0.013722697,2.176625617,1.157221769,4.261990119,0.045812038,DB0940110019211_,3.083208388,0.777775795,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,isosorbide,DB09401
,121680,DB06643,10024855,74,52347,22,7493,0.004778518,0.481477147,0.295556062,0.814635905,0.019728791,DB0664310024855_,3.925676245,-0.730896511,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,121694,DB00973,10050584,34,3817,17,3004,0.156264793,1.573908278,0.853294295,3.010331782,0.29241591,DB0097310050584_,1.229578142,0.453561875,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,ezetimibe,DB00973
,121695,DB00169,10060820,84,38607,29,18146,0.158636878,1.361466119,0.882763286,2.155215181,0.295686451,DB0016910060820_,1.218455673,0.308562148,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,121696,DB00381,10060820,46,29314,24,22863,0.117759395,1.494860886,0.893447595,2.561330552,0.237844298,DB0038110060820_,1.436139028,0.402033149,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,121709,DB01015,10037855,49,9838,46,9335,1,1.010754876,0.661277861,1.547232532,1,DB0101510037855_,0,0.010697454,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,121713,DB00091,10013700,112,5398,12,2658,2.7834421326332e-09,4.595783744,2.52319423,9.176908646,7.07912689465542e-08,DB0009110013700_,16.46353016,1.525139306,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,cyclosporine,DB00091
,121714,DB00761,10013700,205,15102,64,8561,1.71509086133792e-05,1.815740249,1.363334162,2.446405159,0.000174395,DB0076110013700_,8.654186479,0.596493235,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,potassium chloride,DB00761
,121715,DB00091,10042674,43,5467,10,2660,0.038492571,2.092027073,1.033143581,4.67662293,0.102623027,DB0009110042674_,2.276692936,0.738133487,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,121726,DB00338,10048302,147,33527,108,22164,0.405348506,0.899805421,0.69670492,1.165204895,0.575022154,DB0033810048302_,0.553346711,-0.105576738,NA,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,121728,DB00635,10048302,35,33018,53,23741,0.000707449,0.474833172,0.300623539,0.741687531,0.004130103,DB0063510048302_,5.489453017,-0.744791754,NA,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,121734,DB00482,10047513,52,8207,21,3050,0.791661438,0.92023636,0.543683544,1.611252112,0.887231487,DB0048210047513_,0.119649354,-0.083124728,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,celecoxib,DB00482
,121735,DB00927,10047513,58,7439,17,4999,0.001939084,2.292554461,1.314686935,4.204788319,0.009493167,DB0092710047513_,4.657182951,0.829666681,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,famotidine,DB00927
,121761,DB00177,10043607,23,4777,31,2819,0.002796563,0.437875455,0.243318293,0.777452306,0.012759324,DB0017710043607_,4.361492997,-0.825820759,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,valsartan,DB00177
,121766,DB08828,10003239,25,737,35,1107,0.790393847,1.072841832,0.610003173,1.861762828,0.886473405,DB0882810003239_,0.120504154,0.070311046,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,vismodegib,DB08828
,121767,DB00028,10000087,78,13380,28,5587,0.523463729,1.163196953,0.745673298,1.863196122,0.681717293,DB0002810000087_,0.383140234,0.151172208,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,human immunoglobulin g,DB00028
,121785,DB00318,10070863,161,4122,342,1497,1.69329970408233e-75,0.171025641,0.139621856,0.20887666,2.11944679627638e-72,DB0031810070863_,165.0349716,-1.765941786,male,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,codeine,DB00318
,121786,DB00005,10007554,64,128018,38,42381,0.005669563,0.557576261,0.367467677,0.85642449,0.022620629,DB0000510007554_,3.788892981,-0.584155995,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,etanercept,DB00005
,121798,DB00060,10065154,67,9441,16,2449,0.89170925,1.086220861,0.621293044,2.012097322,0.955005127,DB0006010065154_,0.04603857,0.082704572,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,interferon beta-1a,DB00060
,121800,DB00188,10015090,22,7864,35,8793,0.231642018,0.702843111,0.392408273,1.23335895,0.387897474,DB0018810015090_,0.947014218,-0.352621583,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bortezomib,DB00188
,121802,DB00213,10061024,97,18798,93,13328,0.038839324,0.739524112,0.550161055,0.99454535,0.103323224,DB0021310061024_,2.269893107,-0.301748391,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,121804,DB00399,10061024,27,6965,35,4963,0.020043088,0.549732427,0.319598407,0.936096931,0.061863852,DB0039910061024_,2.782819245,-0.598323615,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,zoledronic acid,DB00399
,121805,DB00497,10061024,60,19207,75,16300,0.030174096,0.678933347,0.474945621,0.966932998,0.085076547,DB0049710061024_,2.46420388,-0.38723232,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,oxycodone,DB00497
,121817,DB00788,10028735,49,9307,18,5043,0.198971572,1.474999259,0.842992856,2.693334966,0.347818161,DB0078810028735_,1.056075462,0.388657487,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,naproxen,DB00788
,121821,DB00398,10033553,41,686,61,1477,0.082261143,1.446920108,0.93923227,2.209565662,0.18209821,DB0039810033553_,1.703209124,0.369437234,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,sorafenib,DB00398
,121837,DB10708,10003239,37,983,14,441,0.646507171,1.185508343,0.618481412,2.399241973,0.781918787,DB1070810003239_,0.246004397,0.170171664,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,flax seed,DB10708
,121840,DB00047,10012378,85,9200,59,8459,0.11129398,1.324617046,0.93786148,1.88160355,0.228007915,DB0004710012378_,1.478374936,0.281123396,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,insulin glargine,DB00047
,121851,DB10708,10013573,46,974,17,438,0.577884588,1.216633175,0.675265601,2.290588023,0.726762345,DB1070810013573_,0.319155753,0.196087351,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,flax seed,DB10708
,121852,DB00321,10017885,45,7402,13,2837,0.461817181,1.326658764,0.70202867,2.684906325,0.628981197,DB0032110017885_,0.463653916,0.282663574,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,amitriptyline,DB00321
,121853,DB00472,10017885,55,10704,12,4300,0.057403271,1.841147544,0.972971219,3.781013029,0.138540537,DB0047210017885_,1.976592311,0.610389043,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,121854,DB00814,10017885,59,8228,27,3388,0.635519592,0.899796368,0.560489507,1.478764992,0.773487949,DB0081410017885_,0.256845189,-0.105586799,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,121877,DB00338,10026865,34,33640,17,22255,0.39211018,1.323120223,0.718766689,2.526242091,0.561985241,DB0033810026865_,0.576279691,0.279992752,NA,10026865,Mass,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,121896,DB00047,10028810,71,9214,43,8475,0.030671321,1.518692189,1.024290029,2.275415009,0.08619648,DB0004710028810_,2.451125939,0.417849563,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,121897,DB00230,10028810,341,19333,89,8562,5.19634798586595e-06,1.696809364,1.338041529,2.170662349,6.12218766510473e-05,DB0023010028810_,9.701005971,0.528749643,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,pregabalin,DB00230
,121898,DB00321,10028810,74,7373,31,2819,0.661949034,0.912698005,0.591065557,1.439941583,0.793904753,DB0032110028810_,0.230791783,-0.091350225,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,amitriptyline,DB00321
,121899,DB00814,10028810,131,8156,38,3377,0.060408837,1.427397722,0.985515127,2.110725134,0.144179269,DB0081410028810_,1.936697828,0.355853012,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,meloxicam,DB00814
,121900,DB09270,10028810,51,3063,34,2334,0.58244998,1.142945576,0.723631441,1.825760024,0.730598793,DB0927010028810_,0.313890816,0.133608769,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ubidecarenone,DB09270
,121919,DB00316,10041591,76,65398,26,36927,0.029777594,1.650507958,1.044875481,2.685587306,0.084226108,DB0031610041591_,2.474250332,0.501083094,NA,10041591,Spinal osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,121923,DB00996,10041591,38,38915,19,22406,0.68103317,1.151557443,0.647414246,2.115255409,0.807122451,DB0099610041591_,0.214279887,0.141115324,NA,10041591,Spinal osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,121928,DB00230,10061246,51,19623,16,8635,0.287982344,1.402674936,0.786414078,2.636858607,0.45297205,DB0023010061246_,0.791924856,0.338381083,NA,10061246,Intervertebral disc degeneration,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,121931,DB00338,10061246,47,33627,23,22249,0.271884001,1.352041163,0.804434753,2.333617346,0.434752203,DB0033810061246_,0.832979059,0.301615423,NA,10061246,Intervertebral disc degeneration,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,121956,DB00586,10002034,68,7041,30,2775,0.652129352,0.893357165,0.571940336,1.425631579,0.786384678,DB0058610002034_,0.240309194,-0.112768817,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,diclofenac,DB00586
,121960,DB00115,10007739,102,18323,53,10419,0.6163162,1.09435132,0.777088599,1.556643028,0.757494018,DB0011510007739_,0.277739638,0.090161786,NA,10007739,Cataract,10015919,Eye disorders,Eye,cyanocobalamin,DB00115
,121961,DB00158,10007739,62,16753,41,8063,0.115020105,0.727786466,0.482289039,1.108738667,0.233640144,DB0015810007739_,1.453973193,-0.31774759,NA,10007739,Cataract,10015919,Eye disorders,Eye,folic acid,DB00158
,121962,DB00193,10007739,65,19255,19,8683,0.099173908,1.542694303,0.912923793,2.726150175,0.209590847,DB0019310007739_,1.562597994,0.433530435,NA,10007739,Cataract,10015919,Eye disorders,Eye,tramadol,DB00193
,121966,DB15566,10007739,35,972,27,635,0.596973548,0.846950544,0.492643726,1.47036541,0.742333697,DB1556610007739_,0.29795641,-0.166112975,NA,10007739,Cataract,10015919,Eye disorders,Eye,prednisolone acetate,DB15566
,121967,DB00115,10021688,42,18383,26,10446,0.800746805,0.917934242,0.549460087,1.560384823,0.892281272,DB0011510021688_,0.113973868,-0.085629523,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,cyanocobalamin,DB00115
,121968,DB00338,10021688,52,33622,18,22254,0.019581326,1.91209489,1.099906374,3.474057269,0.060795554,DB0033810021688_,2.800238612,0.648199442,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,omeprazole,DB00338
,121970,DB00480,10021688,103,67325,82,67580,0.122578224,1.260850102,0.933998022,1.706662887,0.245137796,DB0048010021688_,1.405934795,0.231786177,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,lenalidomide,DB00480
,121972,DB00682,10021688,34,19425,19,16345,0.16855108,1.505716962,0.834480109,2.795485025,0.308967723,DB0068210021688_,1.174518462,0.409269172,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,warfarin,DB00682
,121979,DB00586,10030124,59,7050,33,2772,0.129768849,0.703005575,0.450459825,1.114081042,0.255328419,DB0058610030124_,1.365204645,-0.352390456,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,121983,DB01225,10030124,75,4969,61,4579,0.490219532,1.132993222,0.795301167,1.619532473,0.653503053,DB0122510030124_,0.425408074,0.124863,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,121985,DB00115,10056812,60,18365,33,10439,0.914394267,1.033488056,0.664462049,1.633038,0.961701877,DB0011510056812_,0.039050775,0.032939543,NA,10056812,Body height decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,121986,DB00193,10056812,45,19275,15,8687,0.332476894,1.352101571,0.739226618,2.612810424,0.501427283,DB0019310056812_,0.690296681,0.301660101,NA,10056812,Body height decreased,10022891,Investigations,Inv,tramadol,DB00193
,121987,DB00451,10056812,127,47144,30,15389,0.115238103,1.381840897,0.921837388,2.132636895,0.233992549,DB0045110056812_,1.452466006,0.323416593,NA,10056812,Body height decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,121990,DB00682,10056812,39,19420,29,16335,0.628633567,1.131172045,0.681419251,1.897605101,0.76784714,DB0068210056812_,0.264164602,0.123254303,NA,10056812,Body height decreased,10022891,Investigations,Inv,warfarin,DB00682
,122019,DB01136,10018836,36,9848,34,11081,0.474316073,1.191379109,0.724001152,1.964257433,0.639993737,DB0113610018836_,0.446296889,0.175111551,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,122029,DB00820,10008531,170,11745,63,5753,0.067545921,1.321768252,0.9825473,1.797247861,0.156931501,DB0082010008531_,1.851945865,0.278970425,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,122032,DB00820,10060800,94,11821,17,5799,4.04640840896228e-05,2.712423577,1.605257355,4.856666916,0.000368346,DB0082010060800_,7.906488431,0.997842544,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,tadalafil,DB00820
,122033,DB06403,10060800,156,21315,24,6637,0.000768068,2.023808959,1.31011674,3.256672925,0.004421035,DB0640310060800_,5.421381533,0.704981359,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,ambrisentan,DB06403
,122038,DB01609,10035664,53,1531,40,1303,0.59830407,1.127619782,0.728638187,1.757144455,0.743126874,DB0160910035664_,0.296888489,0.120109024,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,deferasirox,DB01609
,122042,DB00230,10013496,149,19525,50,8601,0.104724753,1.312671793,0.945946065,1.848496666,0.218069408,DB0023010013496_,1.52294188,0.272064597,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,122043,DB00215,10049414,35,11068,18,5258,0.770087418,0.923740604,0.508626757,1.734288975,0.874040593,DB0021510049414_,0.134628459,-0.079323979,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,122044,DB00588,10049414,63,16461,42,8426,0.214676838,0.767847641,0.510995542,1.164170817,0.36707405,DB0058810049414_,1.002191681,-0.264163949,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,122047,DB08880,10048959,36,3302,15,794,0.076713668,0.577194614,0.306416845,1.140619337,0.172727322,DB0888010048959_,1.756041099,-0.549575784,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,teriflunomide,DB08880
,122053,DB01136,10005555,43,9841,44,11071,0.668375115,1.099413932,0.70446288,1.714813779,0.798540788,DB0113610005555_,0.224969232,0.094777249,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,carvedilol,DB01136
,122057,DB01067,10028411,49,4312,36,4787,0.063836749,1.510967353,0.960724953,2.396743349,0.15037406,DB0106710028411_,1.894629357,0.412750077,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,glipizide,DB01067
,122058,DB00804,10002855,91,2909,12,887,0.004197459,2.31172295,1.253744957,4.659997694,0.017759292,DB0080410002855_,4.0308464,0.837993112,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,dicyclomine,DB00804
,122061,DB01068,10003246,55,13708,12,6828,0.008758494,2.282895203,1.206898141,4.686460996,0.032025736,DB0106810003246_,3.441215441,0.825444463,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,122063,DB00364,10012378,52,2698,14,1386,0.034960943,1.907816793,1.037395656,3.741246388,0.095351325,DB0036410012378_,2.350187052,0.645959548,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,sucralfate,DB00364
,122064,DB00804,10012378,81,2919,11,888,0.008384546,2.239605589,1.181030822,4.685623516,0.030912098,DB0080410012378_,3.476607649,0.806299774,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,dicyclomine,DB00804
,122068,DB01238,10027599,48,5202,7,3495,1.20645728697432e-05,4.606399383,2.069171863,12.08078818,0.000127999,DB0123810027599_,8.963488815,1.527446507,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,122072,DB01068,10039020,20,13743,44,6796,9.42101518974427e-09,0.224794118,0.125438073,0.389868575,2.13199642068384e-07,DB0106810039020_,15.36103682,-1.492570326,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,122080,DB01104,10059570,48,15415,13,7273,0.075117522,1.742041222,0.928253328,3.506840729,0.170031071,DB0110410059570_,1.771774087,0.555057542,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,sertraline,DB01104
,122082,DB00230,10061623,55,19619,35,8616,0.086643711,0.690124529,0.443298801,1.087331575,0.189462165,DB0023010061623_,1.663565932,-0.370883221,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,122086,DB01068,10061623,69,13694,30,6810,0.593512803,1.143769355,0.734185532,1.821156446,0.739517149,DB0106810061623_,0.301757807,0.13432926,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,122088,DB01275,10047513,22,3957,30,3319,0.09361097,0.615144312,0.337396217,1.105068634,0.20110865,DB0127510047513_,1.603909969,-0.485898385,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,hydralazine,DB01275
,122096,DB00959,10012174,80,7998,56,4946,0.479262954,0.883446487,0.618880987,1.268671595,0.644364554,DB0095910012174_,0.439490635,-0.123924559,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,methylprednisolone,DB00959
,122100,DB08880,10033425,105,3233,22,787,0.571536063,1.161770005,0.722896618,1.945685257,0.72168084,DB0888010033425_,0.326172288,0.149944709,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,teriflunomide,DB08880
,122102,DB01156,10046543,40,13582,20,6308,0.782258309,0.928881667,0.5298525,1.678560316,0.881453237,DB0115610046543_,0.126183328,-0.073773925,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,bupropion,DB01156
,122104,DB01062,10008479,44,4442,20,1725,0.57635837,0.854385026,0.491394843,1.534835417,0.725624091,DB0106210008479_,0.32072318,-0.157373337,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,122105,DB14500,10017577,126,7683,44,4029,0.022387507,1.501655777,1.055125798,2.172409044,0.067491184,DB1450010017577_,2.695758302,0.40656835,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,122106,DB00115,10049848,223,18202,132,10340,0.738946828,0.959716346,0.769272001,1.20107381,0.84978966,DB0011510049848_,0.162766419,-0.041117511,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,122107,DB14500,10049848,66,7743,33,4040,0.9154616,1.043521533,0.675897007,1.639341285,0.962143444,DB1450010049848_,0.03859173,0.042601083,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,potassium,DB14500
,122112,DB00437,10018964,21,6900,33,11513,0.888235014,1.061800991,0.583318667,1.892473262,0.953688875,DB0043710018964_,0.047417788,0.059966514,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,122113,DB00455,10018964,37,9364,15,5103,0.384467342,1.344207068,0.71934447,2.639095775,0.554528319,DB0045510018964_,0.589637402,0.295804299,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,122124,DB00115,10015958,47,18378,19,10453,0.248617923,1.406960921,0.809538422,2.540118372,0.407973661,DB0011510015958_,0.896552663,0.341432003,NA,10015958,Eye pain,10015919,Eye disorders,Eye,cyanocobalamin,DB00115
,122125,DB00695,10015958,49,28000,19,20509,0.019050591,1.888952968,1.091650872,3.398807448,0.059480507,DB0069510015958_,2.82210664,0.63602269,NA,10015958,Eye pain,10015919,Eye disorders,Eye,furosemide,DB00695
,122152,DB00252,10041962,30,2202,35,1873,0.212243322,0.729139049,0.430621044,1.227677534,0.364067543,DB0025210041962_,1.010415871,-0.315890826,NA,10041962,Status epilepticus,10029205,Nervous system disorders,Nerv,phenytoin,DB00252
,122158,DB00480,10052897,57,67371,69,67593,0.326988599,0.828811412,0.573029844,1.194682308,0.495383015,DB0048010052897_,0.702424047,-0.187762638,NA,10052897,Nerve injury,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,122164,DB08895,10053156,86,28028,26,6620,0.278388863,0.78125799,0.498334187,1.263621229,0.442208869,DB0889510053156_,0.815972953,-0.246849851,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,122166,DB01033,10040047,35,1147,38,1266,1,1.016606829,0.618923095,1.665565954,1,DB0103310040047_,0,0.016470443,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,mercaptopurine,DB01033
,122176,DB00788,10046274,19,9337,42,5019,9.99603301619135e-08,0.243198336,0.133438081,0.428015959,1.80892067353246e-06,DB0078810046274_,13.2227802,-1.413877971,male,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,122179,DB00216,10013700,58,865,7,101,0.836456247,0.967491358,0.425193744,2.580896481,0.915542875,DB0021610013700_,0.088238083,-0.033048786,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,eletriptan,DB00216
,122188,DB00734,10001540,19,4031,32,4870,0.262765868,0.717358597,0.383547712,1.306975022,0.424524468,DB0073410001540_,0.856785636,-0.332179428,NA,10001540,Akathisia,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,122207,DB06403,10003246,66,21405,14,6647,0.235472249,1.463907656,0.813300912,2.824554654,0.392603113,DB0640310003246_,0.934956069,0.381109337,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,122230,DB01175,10017885,60,10664,21,4871,0.337278262,1.304992175,0.781356082,2.261710638,0.506432786,DB0117510017885_,0.680363668,0.266197045,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,122232,DB01175,10033557,85,10639,12,4880,2.20982503266623e-05,3.248735671,1.764335858,6.540190692,0.000217426,DB0117510033557_,8.433653801,1.178265896,female,10033557,Palpitations,10007541,Cardiac disorders,Card,escitalopram,DB01175
,122236,DB01175,10038743,39,10685,28,4864,0.085064867,0.634070339,0.379797317,1.071215468,0.186872546,DB0117510038743_,1.677328464,-0.455595386,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,122249,DB01006,10025482,199,5748,6,171,0.833803135,0.98669142,0.436375114,2.759544748,0.913682907,DB0100610025482_,0.090271697,-0.013397933,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,letrozole,DB01006
,122257,DB00351,10053762,41,625,39,825,0.165215842,1.387372664,0.861393466,2.237714071,0.304419643,DB0035110053762_,1.189348125,0.327411789,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,megestrol acetate,DB00351
,122258,DB00947,10053762,70,3102,7,61,0.000984573,0.196861925,0.085734512,0.528495193,0.005434586,DB0094710053762_,5.214972022,-1.625252685,male,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,fulvestrant,DB00947
,122259,DB01006,10053762,95,5852,10,167,0.000846137,0.271184439,0.137922779,0.594437883,0.004795326,DB0100610053762_,5.340113516,-1.304956104,male,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,letrozole,DB01006
,122260,DB00947,10061818,219,2953,9,59,0.053166113,0.486317238,0.235453107,1.130796405,0.130965867,DB0094710061818_,2.032818545,-0.720894115,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,fulvestrant,DB00947
,122278,DB00829,10008190,67,7985,24,4430,0.078133903,1.548738592,0.957111475,2.5860112,0.175242087,DB0082910008190_,1.741586905,0.437440788,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,122290,DB00860,10003549,43,1840,19,1477,0.038116588,1.816355186,1.030914235,3.315256045,0.101828898,DB0086010003549_,2.284461346,0.596831848,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,prednisolone,DB00860
,122299,DB11089,10013952,45,10130,35,8372,0.822606977,1.062598871,0.667336419,1.704484025,0.905737748,DB1108910013952_,0.099005476,0.060717673,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,122307,DB01029,10028813,74,1266,43,858,0.497973768,1.166214037,0.781764222,1.758260831,0.660081963,DB0102910028813_,0.415391266,0.153762636,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,irbesartan,DB01029
,122319,DB01029,10035664,51,1289,25,876,0.193031523,1.386180998,0.835866607,2.353600438,0.340434352,DB0102910035664_,1.077532971,0.326552482,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,irbesartan,DB01029
,122329,DB00335,10043071,36,8430,16,5449,0.255161845,1.454321523,0.785815889,2.809842306,0.415856218,DB0033510043071_,0.877415707,0.374539484,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,atenolol,DB00335
,122332,DB11089,10043071,67,10108,57,8350,0.927927981,0.970996211,0.670997673,1.409293084,0.969862496,DB1108910043071_,0.030600974,-0.029432713,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,docusate,DB11089
,122333,DB00860,10047700,71,1812,33,1463,0.009035852,1.736847808,1.126747381,2.726674074,0.032827556,DB0086010047700_,3.416486982,0.552071866,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,prednisolone,DB00860
,122335,DB00843,10053762,65,2129,89,2084,0.048673044,0.714958484,0.508072305,1.001612701,0.122568593,DB0084310053762_,2.099084462,-0.335530802,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,donepezil,DB00843
,122357,DB00695,10008629,59,27990,46,20482,0.76725726,0.938573417,0.62723261,1.412104859,0.872083072,DB0069510008629_,0.136870593,-0.063394198,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,furosemide,DB00695
,122371,DB00441,10020772,47,2227,19,1875,0.006014326,2.082303968,1.193993014,3.771384051,0.02371002,DB0044110020772_,3.741857533,0.733474958,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,gemcitabine,DB00441
,122374,DB00112,10018964,22,5911,42,4049,9.47278957219598e-05,0.358842604,0.203681204,0.616012111,0.000760979,DB0011210018964_,7.180905016,-1.024871416,male,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bevacizumab,DB00112
,122399,DB01248,10010774,80,2620,40,1334,1,1.018316495,0.684012865,1.53709467,1,DB0124810010774_,0,0.018150769,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,docetaxel,DB01248
,122401,DB00424,10012735,91,1103,25,403,0.231416993,1.329671794,0.832210185,2.193653983,0.387636735,DB0042410012735_,0.947686627,0.28493214,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,hyoscyamine,DB00424
,122409,DB00758,10002388,24,8276,34,10040,0.599001607,0.856346185,0.485443417,1.488492855,0.743713444,DB0075810002388_,0.296099475,-0.155080563,NA,10002388,Angina unstable,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,122412,DB00264,10022081,56,29551,27,24865,0.02003049,1.745159316,1.083614459,2.874592388,0.061842676,DB0026410022081_,2.7831616,0.55684585,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,122416,DB01076,10022081,54,25693,29,25554,0.008012687,1.851962469,1.158082839,3.017397969,0.029817156,DB0107610022081_,3.512671349,0.616245871,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,122430,DB00016,10010774,87,2675,47,2243,0.017347405,1.55199037,1.071070336,2.273120445,0.055283287,DB0001610010774_,2.895284641,0.439538217,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,erythropoietin,DB00016
,122433,DB00635,10024774,96,32957,57,23737,0.286063724,1.213029043,0.864724435,1.71516507,0.450776955,DB0063510024774_,0.796782619,0.193120573,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,122436,DB00016,10029331,35,2727,25,2265,0.603633852,1.162781371,0.674091783,2.033320155,0.747265626,DB0001610029331_,0.291334567,0.150814869,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,erythropoietin,DB00016
,122460,DB01073,10061818,17,1048,34,1616,0.469514354,0.771064259,0.401799582,1.427525753,0.635850236,DB0107310061818_,0.452792222,-0.259983564,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,fludarabine,DB01073
,122463,DB00343,10016322,152,8584,50,5045,0.000296589,1.786602511,1.287381099,2.51619049,0.001998676,DB0034310016322_,6.215270136,0.580315778,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,122465,DB01377,10016322,60,3736,29,2641,0.103946957,1.462479702,0.921131846,2.370308889,0.216939597,DB0137710016322_,1.528136318,0.380133421,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,122467,DB09153,10016322,62,7737,33,5666,0.145557287,1.375850858,0.886558632,2.170353214,0.277816868,DB0915310016322_,1.280793131,0.319072345,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,122478,DB00646,10027175,44,3409,8,1992,0.001223395,3.213286345,1.492355948,7.919779558,0.006496353,DB0064610027175_,5.036514357,1.167294197,female,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,nystatin,DB00646
,122479,DB00727,10027175,47,3796,34,4139,0.0738843,1.507171248,0.946719308,2.422024575,0.167982773,DB0072710027175_,1.783893847,0.410234548,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,122483,DB00230,10028997,72,19602,36,8615,0.530888339,0.879004377,0.580823457,1.351492247,0.687850894,DB0023010028997_,0.374183189,-0.128965402,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pregabalin,DB00230
,122486,DB00722,10028997,44,25359,34,25998,0.256989121,1.326714986,0.828524911,2.141128622,0.417875598,DB0072210028997_,0.872571504,0.282705952,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lisinopril,DB00722
,122496,DB00497,10048439,65,19202,12,16363,2.67974194905807e-08,4.615579755,2.470088973,9.393654124,5.46023388612336e-07,DB0049710048439_,14.42060403,1.529437484,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,122498,DB00722,10048439,60,25343,6,26026,9.31721770526508e-13,10.26827733,4.45050396,29.09607167,4.18995838122999e-11,DB0072210048439_,23.89574522,2.329059272,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,122500,DB00736,10048439,39,10552,11,5542,0.073328735,1.862038144,0.934338399,4.033974419,0.167059223,DB0073610048439_,1.789406899,0.621671664,NA,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,122518,DB00997,10013709,105,5226,94,3420,0.033370696,0.731042359,0.546222812,0.979551117,0.092084273,DB0099710013709_,2.385051111,-0.313283875,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,122532,DB00316,10021114,112,65362,29,36924,9.76312838629659e-05,2.181724493,1.439120927,3.405883623,0.000780605,DB0031610021114_,7.155441548,0.780115616,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,acetaminophen,DB00316
,122534,DB01104,10021114,37,15426,13,7273,0.448326218,1.341924082,0.696620671,2.752691042,0.616073538,DB0110410021114_,0.484388943,0.294104466,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,sertraline,DB01104
,122558,DB00924,10003553,86,10076,9,4242,4.03287674790332e-06,4.022927792,2.020708538,9.103939894,4.89513578012648e-05,DB0092410003553_,9.924683451,1.392009944,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,122571,DB00531,10028334,45,7207,20,6496,0.008504486,2.02787045,1.171754334,3.629806446,0.031277518,DB0053110028334_,3.464855719,0.706986203,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclophosphamide,DB00531
,122589,DB00112,10006002,63,5870,23,4068,0.007921892,1.898139638,1.158651895,3.212216683,0.029552672,DB0011210006002_,3.521581126,0.640874269,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bevacizumab,DB00112
,122653,DB00196,10008469,41,5042,13,3272,0.024624832,2.046520461,1.073011426,4.16925565,0.072681343,DB0019610008469_,2.621670555,0.716141015,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,122654,DB00863,10008469,121,10552,56,5784,0.305600565,1.18434253,0.854414097,1.6590482,0.472381431,DB0086310008469_,0.749968503,0.169187793,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,122655,DB01234,10008469,166,31459,123,32765,0.00457616,1.405606357,1.105967458,1.790368949,0.019023305,DB0123410008469_,3.962090485,0.34046878,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,122656,DB00863,10010774,263,10410,130,5710,0.364063015,1.109687072,0.893666176,1.3834756,0.533669621,DB0086310010774_,0.627978319,0.104078059,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,122658,DB01234,10024264,95,31530,112,32776,0.403465908,0.881736103,0.663373644,1.169972599,0.573202247,DB0123410024264_,0.556516662,-0.125862471,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,122659,DB00196,10029354,68,5015,91,3194,5.17649954494603e-06,0.475953868,0.341298944,0.661084708,6.10427503539284e-05,DB0019610029354_,9.703936114,-0.742434346,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,fluconazole,DB00196
,122660,DB00196,10033775,56,5027,21,3264,0.034356126,1.731341851,1.02959354,3.01659424,0.094121714,DB0019610033775_,2.363166505,0.548896744,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,fluconazole,DB00196
,122661,DB00863,10033775,137,10536,34,5806,1.1870540854572e-05,2.220364331,1.513489603,3.339758862,0.000126144,DB0086310033775_,8.978086503,0.797671295,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,122665,DB00073,10047513,31,7375,25,6382,0.89337054,1.073059873,0.612441737,1.897762229,0.955535825,DB0007310047513_,0.045483023,0.070514261,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,rituximab,DB00073
,122697,DB00421,10048294,48,8855,47,5205,0.014102919,0.600360107,0.392445915,0.918824676,0.046871209,DB0042110048294_,3.060351682,-0.510225625,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,spironolactone,DB00421
,122722,DB00688,10008479,88,6402,33,5345,4.75068250266413e-05,2.226193229,1.47391627,3.435551875,0.000422792,DB0068810008479_,7.768629646,0.800293054,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,122730,DB00635,10040979,66,32987,34,23760,0.127843387,1.39818862,0.910692723,2.182217623,0.252592433,DB0063510040979_,1.375978027,0.335177556,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,122733,DB00531,10041349,38,7214,38,6478,0.646965482,0.897983736,0.556724676,1.448476294,0.782313016,DB0053110041349_,0.245500343,-0.107603322,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,122754,DB00624,10012378,6,556,80,4316,0.231979469,0.582246688,0.206533076,1.332718036,0.388319079,DB0062410012378_,0.94592791,-0.540861059,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,testosterone,DB00624
,122755,DB01217,10013573,93,2661,10,258,0.724055926,0.901745726,0.461485917,1.966786364,0.837833638,DB0121710013573_,0.176935721,-0.103422699,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,anastrozole,DB01217
,122762,DB00572,10009887,31,2871,36,2090,0.061978015,0.626935295,0.373667865,1.046248352,0.14711628,DB0057210009887_,1.916531981,-0.466911942,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,atropine,DB00572
,122791,DB00635,10031161,188,32865,34,23760,2.1768812742323e-17,3.997418234,2.761789276,5.944863173,1.75789014725641e-15,DB0063510031161_,33.97466208,1.385648711,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,122794,DB00993,10038695,35,3214,19,1600,0.772442743,0.917059303,0.508536622,1.702764482,0.875421786,DB0099310038695_,0.133049467,-0.086583138,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azathioprine,DB00993
,122815,DB00047,10003246,51,9234,25,8493,0.010902203,1.876224874,1.140072523,3.162921996,0.038144513,DB0004710003246_,3.266373351,0.629261712,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin glargine,DB00047
,122817,DB01156,10003246,60,13562,14,6314,0.017156581,1.995220946,1.100927174,3.869397624,0.05478143,DB0115610003246_,2.90440402,0.690754794,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,122842,DB00047,10017577,102,9183,57,8461,0.002387073,1.648726713,1.179141514,2.324946727,0.011239447,DB0004710017577_,4.488325638,0.500003301,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,122843,DB00706,10017577,24,1051,203,15722,0.012739316,1.768483399,1.10220166,2.721708061,0.043181755,DB0070610017577_,3.142337209,0.570122342,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,122844,DB01156,10017577,166,13456,53,6275,0.015906495,1.460570823,1.064416588,2.032523764,0.051608002,DB0115610017577_,2.964078548,0.378827334,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,122845,DB04861,10017577,41,1924,14,1373,0.018241227,2.089446034,1.110607568,4.166620909,0.057452598,DB0486110017577_,2.856795055,0.736898975,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,nebivolol,DB04861
,122846,DB00047,10022004,37,9248,21,8497,0.086826408,1.618776925,0.92226306,2.913244659,0.189770115,DB0004710022004_,1.661941863,0.481670879,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,122847,DB00331,10022004,104,24842,67,20685,0.106386,1.292482206,0.941168533,1.78520063,0.220715577,DB0033110022004_,1.510880388,0.25656456,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,122848,DB00381,10022004,131,29229,78,22809,0.059511573,1.310588488,0.98220132,1.758623606,0.142579299,DB0038110022004_,1.94785695,0.270476264,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,122859,DB00331,10048393,83,24863,32,20720,0.000152383,2.161464948,1.421033999,3.361476042,0.001142435,DB0033110048393_,6.774593516,0.770786208,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,metformin,DB00331
,122860,DB00381,10048393,103,29257,23,22864,2.15689257526701e-09,3.499568489,2.209593977,5.76673636,5.6000203108214e-08,DB0038110048393_,16.69791052,1.252639672,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,122863,DB00331,10050256,45,24901,23,20729,0.06683729,1.628698339,0.964455353,2.821339093,0.155635911,DB0033110050256_,1.860235901,0.487781131,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,metformin,DB00331
,122864,DB00641,10050256,33,14091,29,12446,1,1.005087574,0.591280976,1.717043796,1,DB0064110050256_,0,0.005074676,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,122866,DB00722,10050256,57,25346,42,25990,0.108095213,1.391610335,0.917507213,2.125912228,0.223187045,DB0072210050256_,1.499745091,0.330461591,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,122867,DB01050,10050256,39,18069,14,9357,0.309658556,1.442559113,0.765749252,2.877855463,0.477110041,DB0105010050256_,0.740008121,0.366418698,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,122893,DB00331,10067585,80,24866,65,20687,0.933503508,1.023927249,0.728484293,1.443803195,0.974140569,DB0033110067585_,0.026199665,0.023645479,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,122908,DB00482,10022061,72,8187,12,3059,0.006508993,2.241745876,1.2057111,4.545341788,0.025271623,DB0048210022061_,3.678073143,0.807254971,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,122918,DB00441,10010774,82,2192,53,1841,0.159730183,1.299342629,0.90330306,1.882636069,0.297102775,DB0044110010774_,1.213677157,0.261858467,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,gemcitabine,DB00441
,122919,DB00773,10010774,35,2288,31,2796,0.213722688,1.379609372,0.823439633,2.321432069,0.36589057,DB0077310010774_,1.00542098,0.321800395,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,etoposide,DB00773
,122925,DB00773,10029331,30,2293,58,2769,0.039875544,0.624671312,0.386609352,0.990757188,0.105445541,DB0077310029331_,2.249560661,-0.470529668,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,etoposide,DB00773
,122940,DB01050,10020646,25,18083,30,9341,0.002423768,0.430478315,0.24261073,0.75770244,0.011379592,DB0105010020646_,4.475933683,-0.842858327,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,ibuprofen,DB01050
,122947,DB09153,10030095,39,7760,18,5681,0.108504726,1.586134828,0.884933822,2.949007057,0.223786475,DB0915310030095_,1.497062919,0.461300131,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,122948,DB09153,10047895,102,7697,77,5622,0.878964656,0.967548542,0.711176503,1.32092528,0.94911728,DB0915310047895_,0.052222905,-0.032989683,NA,10047895,Weight decreased,10022891,Investigations,Inv,sodium chloride,DB09153
,122960,DB00343,10003119,39,8697,36,5059,0.054144609,0.63021995,0.38968561,1.021656749,0.132723215,DB0034310003119_,2.019489406,-0.461686394,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,diltiazem,DB00343
,122969,DB00661,10013710,50,3478,28,1567,0.388520496,0.804606653,0.494715117,1.332676908,0.558504853,DB0066110013710_,0.582491971,-0.217401751,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,verapamil,DB00661
,122973,DB00335,10040741,38,8428,24,5441,1,1.022177544,0.596749877,1.783411031,1,DB0033510040741_,0,0.021935199,NA,10040741,Sinus bradycardia,10007541,Cardiac disorders,Card,atenolol,DB00335
,122980,DB06273,10033371,159,4936,33,1377,0.131329143,1.344063667,0.91421895,2.029305878,0.257656638,DB0627310033371_,1.356127442,0.295697612,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,123001,DB00441,10021097,33,2241,40,1854,0.122899636,0.682600731,0.415309596,1.115055807,0.245575045,DB0044110021097_,1.404152696,-0.381845172,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,gemcitabine,DB00441
,123003,DB00441,10021143,33,2241,27,1867,1,1.018243003,0.591344691,1.767572123,1,DB0044110021143_,0,0.018078596,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gemcitabine,DB00441
,123005,DB00515,10021143,17,1853,41,2110,0.007978292,0.472238591,0.250624304,0.853136026,0.029722828,DB0051510021143_,3.515839906,-0.750270932,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cisplatin,DB00515
,123012,DB00843,10010774,28,2166,38,2135,0.216189547,0.726352363,0.427655684,1.220005188,0.36885254,DB0084310010774_,0.997358334,-0.319720033,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,donepezil,DB00843
,123013,DB01043,10010774,31,1370,40,1370,0.33645858,0.77507221,0.465813525,1.278860833,0.505525715,DB0104310010774_,0.682156371,-0.25479908,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,memantine,DB01043
,123038,DB00169,10018830,36,38655,25,18150,0.13267874,0.67612933,0.394672113,1.175470298,0.259551273,DB0016910018830_,1.348801011,-0.391370904,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,123044,DB00761,10018830,35,15272,16,8609,0.560473194,1.233152921,0.664299776,2.38750412,0.713105082,DB0076110018830_,0.338126489,0.20957424,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,123046,DB00904,10018830,56,23013,33,14423,0.827918534,1.063551941,0.67940944,1.689154912,0.909547717,DB0090410018830_,0.094807818,0.061614194,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,123049,DB00016,10035226,33,2729,30,2260,0.799208553,0.910973798,0.536786181,1.551524244,0.891545906,DB0001610035226_,0.11479835,-0.093241144,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,erythropoietin,DB00016
,123050,DB00331,10035226,79,24867,108,20644,0.000879627,0.607273496,0.448162575,0.819757106,0.004958392,DB0033110035226_,5.306673707,-0.49877602,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metformin,DB00331
,123051,DB00678,10035226,71,15528,69,10655,0.046926194,0.706092376,0.499247876,0.999060648,0.119318501,DB0067810035226_,2.125958883,-0.348009205,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,losartan,DB00678
,123054,DB06228,10035226,74,15838,78,15998,0.807775599,0.958291461,0.687150364,1.335475471,0.896255547,DB0622810035226_,0.109529698,-0.042603309,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,rivaroxaban,DB06228
,123060,DB00451,10048709,45,47226,11,15408,0.441046322,1.334683446,0.679470433,2.862422144,0.609222901,DB0045110048709_,0.495571067,0.288694145,NA,10048709,Urosepsis,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,123061,DB00480,10048709,25,67403,35,67627,0.244998388,0.716664183,0.411116744,1.232208621,0.403748128,DB0048010048709_,0.906964041,-0.333147913,NA,10048709,Urosepsis,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,123078,DB00541,10038435,45,3089,63,4234,1,0.979051422,0.650661471,1.462703796,1,DB0054110038435_,0,-0.021171112,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,vincristine,DB00541
,123089,DB01276,10037844,69,1948,40,1471,0.202038168,1.302508526,0.864265445,1.986010509,0.351402697,DB0127610037844_,1.045822428,0.26429204,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,exenatide,DB01276
,123107,DB06285,10020100,71,8779,13,1093,0.219090536,0.680004426,0.371797821,1.343826926,0.372400074,DB0628510020100_,0.987786535,-0.385655973,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,teriparatide,DB06285
,123108,DB00264,10029366,64,29543,60,24832,0.588418903,0.896575883,0.620194923,1.297636402,0.735348779,DB0026410029366_,0.307410363,-0.109172346,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,metoprolol,DB00264
,123109,DB00399,10029366,59,6933,39,4959,0.758050367,1.082092784,0.708762589,1.668505534,0.864834475,DB0039910029366_,0.145217149,0.078896929,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,zoledronic acid,DB00399
,123110,DB00404,10029366,35,19857,25,9837,0.170630672,0.693537754,0.403176783,1.209599553,0.311698327,DB0040410029366_,1.165719461,-0.3659496,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,alprazolam,DB00404
,123127,DB00264,10047942,336,29271,284,24608,0.967666056,0.994625501,0.845934095,1.170105165,1,DB0026410047942_,0,-0.005388994,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,metoprolol,DB00264
,123128,DB00404,10047942,218,19674,77,9785,0.010684449,1.408086106,1.079813903,1.852590755,0.037533011,DB0040410047942_,3.282534439,0.342231411,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,alprazolam,DB00404
,123129,DB00973,10047942,29,3822,30,2991,0.294558528,0.756526303,0.437100309,1.307678071,0.460395541,DB0097310047942_,0.775669286,-0.279017977,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,ezetimibe,DB00973
,123130,DB01039,10047942,45,2928,33,3018,0.140430087,1.405465357,0.874337606,2.280481023,0.270455822,DB0103910047942_,1.307646514,0.340368463,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,fenofibrate,DB01039
,123131,DB06228,10047942,119,15793,84,15992,0.011259959,1.434494224,1.07484325,1.921712508,0.039126321,DB0622810047942_,3.24095988,0.36081233,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,rivaroxaban,DB06228
,123133,DB01098,10005557,77,8072,85,7124,0.178363067,0.799507366,0.57859433,1.103229914,0.32178683,DB0109810005557_,1.133865972,-0.223759533,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,rosuvastatin,DB01098
,123150,DB00341,10015967,43,11362,17,5051,0.779809681,1.124443211,0.627391205,2.105087125,0.880132524,DB0034110015967_,0.127682787,0.11728799,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,cetirizine,DB00341
,123154,DB00993,10016256,148,3101,72,1547,0.883877981,1.025453258,0.763231204,1.388027983,0.951576192,DB0099310016256_,0.04963552,0.025134718,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,azathioprine,DB00993
,123157,DB00091,10037087,138,5372,17,2653,3.47654774333351e-10,4.008201047,2.408148271,7.096274532,1.04554985621878e-08,DB0009110037087_,18.37613782,1.388342524,female,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,cyclosporine,DB00091
,123158,DB00993,10037087,73,3176,19,1600,0.009825253,1.935337715,1.150715238,3.408693269,0.03507375,DB0099310037087_,3.35030228,0.660281841,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,azathioprine,DB00993
,123159,DB00363,10012735,20,4608,43,6845,0.197871145,0.690933274,0.38451826,1.202068509,0.346412884,DB0036310012735_,1.06012391,-0.369712025,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,clozapine,DB00363
,123246,DB01234,10001949,87,31538,84,32804,0.646369151,1.077260672,0.788633623,1.472298878,0.781841796,DB0123410001949_,0.246102866,0.074421404,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,123253,DB01234,10057668,85,31540,82,32806,0.642578157,1.078164852,0.786239173,1.479157898,0.779030804,DB0123410057668_,0.249704691,0.075260385,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,123266,DB00198,10019211,73,1202,30,973,0.002165718,1.969158192,1.259057962,3.148319617,0.010386987,DB0019810019211_,4.567201462,0.677606138,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,oseltamivir,DB00198
,123270,DB06674,10019974,48,4458,8,1482,0.085760694,1.994538014,0.932467592,4.893808162,0.187953461,DB0667410019974_,1.671560895,0.690412451,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,golimumab,DB06674
,123271,DB06674,10020772,36,4470,15,1475,0.420666615,0.791976379,0.421465403,1.561660071,0.589671332,DB0667410020772_,0.528189961,-0.233223712,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,golimumab,DB06674
,123285,DB00423,10011224,39,2428,17,1023,0.88363834,0.966598963,0.531252306,1.831212043,0.951357163,DB0042310011224_,0.049865721,-0.033971592,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methocarbamol,DB00423
,123287,DB00787,10011224,318,16682,207,17041,4.83568021071168e-07,1.569261054,1.311354255,1.881126699,7.53666494743887e-06,DB0078710011224_,11.79573079,0.450604842,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,123289,DB00653,10013968,57,1035,34,788,0.280193619,1.276224457,0.81127504,2.034255831,0.444015751,DB0065310013968_,0.811895241,0.243906076,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium sulfate,DB00653
,123299,DB00787,10020642,98,16902,69,17179,0.019919679,1.443543656,1.049285178,1.995306563,0.061570745,DB0078710020642_,2.787568438,0.367100963,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,123304,DB00787,10028391,49,16951,25,17223,0.004943958,1.991399771,1.205737895,3.36629275,0.020290724,DB0078710028391_,3.897591456,0.688837794,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,123309,DB00653,10035664,44,1048,56,766,0.009170161,0.574474123,0.373675152,0.878403107,0.033214507,DB0065310035664_,3.404768541,-0.554300225,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,magnesium sulfate,DB00653
,123348,DB00542,10053762,41,1645,28,1396,0.395239162,1.242552949,0.745650393,2.098091733,0.564978732,DB0054210053762_,0.570967192,0.217168093,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,benazepril,DB00542
,123377,DB01075,10016326,46,19902,23,11074,0.708141468,1.112862867,0.660418902,1.924635823,0.825633679,DB0107510016326_,0.191604092,0.106935855,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,123383,DB01097,10000081,52,6213,10,1493,0.628964826,1.249537622,0.626305113,2.764303505,0.768088666,DB0109710000081_,0.263850102,0.222773581,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,leflunomide,DB01097
,123384,DB01097,10002855,52,6213,6,1497,0.094414643,2.088009575,0.894879076,5.959617725,0.202380338,DB0109710002855_,1.59760649,0.736211256,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,leflunomide,DB01097
,123385,DB05351,10002855,49,2674,19,1112,0.893380526,1.072451764,0.616676896,1.938332551,0.955535825,DB0535110002855_,0.045483023,0.069947396,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,dexlansoprazole,DB05351
,123386,DB00727,10005750,45,3798,36,4137,0.180633325,1.361512052,0.856839989,2.177461689,0.324634846,DB0072710005750_,1.125054279,0.308595885,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,nitroglycerin,DB00727
,123408,DB00678,10043882,40,15559,41,10683,0.088701051,0.669891462,0.422025761,1.062598912,0.193101468,DB0067810043882_,1.644539485,-0.400639577,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,losartan,DB00678
,123415,DB00678,10048865,46,15553,33,10691,0.908815957,0.958154617,0.599080667,1.547862262,0.95913476,DB0067810048865_,0.041723693,-0.042746118,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,losartan,DB00678
,123439,DB00476,10013538,42,17215,10,6167,0.273405608,1.50450754,0.742282349,3.365027021,0.436376501,DB0047610013538_,0.829249873,0.408465629,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,duloxetine,DB00476
,123446,DB00343,10018884,143,8593,62,5033,0.049089451,1.350881877,0.993798904,1.854481227,0.123262917,DB0034310018884_,2.093435667,0.300757621,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,diltiazem,DB00343
,123482,DB00213,10059570,44,18851,26,13395,0.469773923,1.202487241,0.723831768,2.035462939,0.636075111,DB0021310059570_,0.452438623,0.184392113,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,pantoprazole,DB00213
,123487,DB00758,10006451,71,8229,49,10025,0.002293693,1.765143107,1.207954446,2.597717606,0.010877712,DB0075810006451_,4.521039378,0.568231767,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,clopidogrel,DB00758
,123488,DB01098,10011224,150,7999,94,7115,0.007998926,1.419357055,1.087217117,1.860675386,0.029774378,DB0109810011224_,3.514107064,0.350203991,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,123507,DB00005,10027091,41,128041,20,42399,0.1811079,0.678831017,0.388642343,1.223160532,0.325222522,DB0000510027091_,1.123245648,-0.387383053,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,123510,DB00433,10003445,37,7619,27,5993,0.801874907,1.077929214,0.637946071,1.842986436,0.892815853,DB0043310003445_,0.113374931,0.075041806,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,123521,DB00338,10073133,17,33657,37,22235,3.38669190985955e-05,0.303541435,0.160264958,0.552889829,0.000315615,DB0033810073133_,8.060987598,-1.192237155,male,10073133,Plasma cell myeloma recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,omeprazole,DB00338
,123535,DB00635,10033295,67,32986,55,23739,0.464384098,0.876691666,0.604285766,1.276520549,0.631503752,DB0063510033295_,0.459651395,-0.131599926,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,123547,DB00996,10024670,53,38900,29,22396,0.908785184,1.052204025,0.656770364,1.716907095,0.95913476,DB0099610024670_,0.041723693,0.050887035,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,gabapentin,DB00996
,123550,DB01076,10024670,38,25709,41,25542,0.736650243,0.920830908,0.576140154,1.468368932,0.848001912,DB0107610024670_,0.164872389,-0.082478856,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,atorvastatin,DB01076
,123565,DB00321,10014380,28,7419,32,2818,3.06891893023686e-05,0.332395577,0.192444588,0.571071038,0.000289528,DB0032110014380_,8.147256822,-1.101429523,male,10014380,Electrocardiogram QRS complex prolonged,10022891,Investigations,Inv,amitriptyline,DB00321
,123569,DB00321,10038695,56,7391,41,2809,0.001941998,0.519112286,0.33998401,0.798642677,0.009505665,DB0032110038695_,4.655867386,-0.655635068,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amitriptyline,DB00321
,123575,DB00112,10029366,242,5691,47,4044,1.09979018966803e-19,3.658374292,2.659761211,5.126556131,1.10758563737257e-17,DB0011210029366_,39.04176404,1.297018866,female,10029366,Neutrophil count decreased,10022891,Investigations,Inv,bevacizumab,DB00112
,123582,DB00370,10002855,132,4409,67,3596,0.001841554,1.606768857,1.184384913,2.196940625,0.009090189,DB0037010002855_,4.700559589,0.474225241,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,mirtazapine,DB00370
,123589,DB00476,10019070,36,17221,27,6150,0.005873846,0.47616671,0.280885509,0.816255256,0.023281306,DB0047610019070_,3.760104549,-0.741987255,NA,10019070,"Hallucination, auditory",10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,123599,DB01076,10019075,22,25725,33,25550,0.139526597,0.662140416,0.367667549,1.170669432,0.269151373,DB0107610019075_,1.312481332,-0.412277636,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,123600,DB01104,10019075,28,15435,30,7256,0.001828688,0.438772089,0.252385453,0.76063016,0.009041962,DB0110410019075_,4.705879101,-0.823775159,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,sertraline,DB01104
,123604,DB01175,10020937,140,10584,16,4876,5.59036732462136e-10,4.031304355,2.393600164,7.254799593,1.62817512606839e-08,DB0117510020937_,17.93322091,1.394089985,female,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,123605,DB00370,10033775,35,4506,23,3640,0.50819383,1.229247458,0.704678906,2.183325198,0.66876728,DB0037010033775_,0.402319143,0.206402159,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,mirtazapine,DB00370
,123607,DB01175,10033775,133,10591,31,4861,0.000478176,1.969074831,1.321504721,3.017690949,0.002977345,DB0117510033775_,5.816723298,0.677563804,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,123630,DB01062,10000081,43,4443,17,1728,1,0.983757236,0.547777062,1.845013744,1,DB0106210000081_,0,-0.016376124,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,oxybutynin,DB01062
,123631,DB01062,10002855,76,4410,20,1725,0.135966278,1.486365343,0.895344723,2.577060968,0.264037059,DB0106210002855_,1.33166581,0.396333773,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,oxybutynin,DB01062
,123633,DB01062,10010305,75,4411,43,1702,0.048615975,0.673046615,0.454534359,1.007678567,0.122465944,DB0106210010305_,2.099922296,-0.395940687,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,oxybutynin,DB01062
,123661,DB00829,10001760,88,7964,12,4442,1.41713948155436e-07,4.089893184,2.224329531,8.226409022,2.49243969706633e-06,DB0082910001760_,12.90224853,1.408518853,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,diazepam,DB00829
,123665,DB00285,10028372,94,10857,29,3689,0.754820894,1.101350425,0.718175419,1.735809835,0.862329068,DB0028510028372_,0.148118331,0.096537086,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,venlafaxine,DB00285
,123666,DB08868,10028372,278,8924,87,2424,0.270492745,0.867947215,0.676851752,1.122187021,0.433185954,DB0886810028372_,0.836588189,-0.141624379,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,fingolimod,DB08868
,123667,DB00285,10029148,39,10912,11,3707,0.74458765,1.204433749,0.604157499,2.610296136,0.854143649,DB0028510029148_,0.157655892,0.186009539,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,venlafaxine,DB00285
,123675,DB00333,10010774,53,3018,39,3113,0.115914216,1.40166917,0.90659985,2.183889914,0.235038585,DB0033310010774_,1.448005587,0.337663791,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,methadone,DB00333
,123686,DB00480,10017412,257,67171,280,67382,0.341868819,0.920762299,0.77399733,1.094896229,0.5110776,DB0048010017412_,0.671233841,-0.082553366,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,lenalidomide,DB00480
,123699,DB08868,10003988,284,8918,73,2438,0.694431461,1.063529553,0.816206812,1.4006597,0.816055928,DB0886810003988_,0.203272387,0.061593144,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fingolimod,DB08868
,123709,DB00864,10047513,34,6835,35,8357,0.544597978,1.187727066,0.717865544,1.963184419,0.6995167,DB0086410047513_,0.357365611,0.172041452,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,tacrolimus,DB00864
,123716,DB00480,10043882,112,67316,109,67553,0.840134553,1.031147403,0.78480524,1.355154755,0.918209427,DB0048010043882_,0.08532978,0.030672166,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,lenalidomide,DB00480
,123762,DB09270,10000059,67,3047,36,2332,0.107703207,1.424297156,0.932574449,2.207225904,0.222683772,DB0927010000059_,1.502002576,0.353678468,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ubidecarenone,DB09270
,123771,DB00722,10040070,73,25330,60,25972,0.224230412,1.247495401,0.873965515,1.786585067,0.378797286,DB0072210040070_,0.970754083,0.221137862,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,lisinopril,DB00722
,123775,DB01156,10028334,148,13474,35,6293,0.000161536,1.974885517,1.356734963,2.946013961,0.001201804,DB0115610028334_,6.723931876,0.680510431,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,123777,DB00736,10052904,58,10533,25,5528,0.487169305,1.217551553,0.748741917,2.0338317,0.651053471,DB0073610052904_,0.429163504,0.196841918,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,123779,DB00005,10061160,195,127887,43,42376,0.016087283,1.502615946,1.075176014,2.142812294,0.052042692,DB0000510061160_,2.955690905,0.407207553,NA,10061160,Foot operation,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,123798,DB01060,10003553,54,8533,16,5065,0.012858514,2.003231289,1.128053008,3.753749597,0.04349045,DB0106010003553_,3.135213898,0.694761521,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amoxicillin,DB01060
,123799,DB00043,10006451,69,6344,15,2285,0.081529324,1.656829503,0.936007893,3.125166432,0.180920075,DB0004310006451_,1.709699922,0.504905838,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,omalizumab,DB00043
,123801,DB06282,10006451,44,1496,9,524,0.15447847,1.712092967,0.817642157,4.016613487,0.290085128,DB0628210006451_,1.237580855,0.537716579,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,levocetirizine,DB06282
,123804,DB01611,10013781,73,11840,9,2352,0.231310871,1.611208915,0.802346218,3.668793879,0.387520713,DB0161110013781_,0.947985977,0.476984776,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,123807,DB00471,10013786,74,14115,20,5445,0.167590851,1.427236789,0.860426925,2.472616329,0.307663468,DB0047110013786_,1.178748731,0.355740259,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,123809,DB01060,10013786,43,8544,19,5062,0.356535118,1.340808584,0.763811054,2.439062111,0.526242168,DB0106010013786_,0.641993776,0.293272853,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,amoxicillin,DB01060
,123813,DB00668,10024855,53,10038,30,4273,0.229181955,0.752038984,0.471085961,1.221017278,0.384898582,DB0066810024855_,0.954775404,-0.284967116,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,epinephrine,DB00668
,123815,DB01060,10024855,35,8552,19,5062,0.887949976,1.090362077,0.606109334,2.020078997,0.953581309,DB0106010024855_,0.047530583,0.086509822,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,amoxicillin,DB01060
,123816,DB01611,10024855,66,11847,7,2354,0.11607859,1.873380336,0.858727273,4.846001906,0.235272062,DB0161110024855_,1.447012724,0.627744465,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,hydroxychloroquine,DB01611
,123824,DB00972,10037087,57,2447,18,1161,0.168292081,1.502298438,0.866625122,2.725250267,0.308595162,DB0097210037087_,1.175725015,0.406996228,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,azelastine,DB00972
,123825,DB06282,10037087,73,1467,12,521,0.011045028,2.159813185,1.15284212,4.406820723,0.03852678,DB0628210037087_,3.256401693,0.77002173,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,levocetirizine,DB06282
,123826,DB00394,10037844,40,1599,10,784,0.066375133,1.960751041,0.957286831,4.420623021,0.154834077,DB0039410037844_,1.865401205,0.673327584,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,beclomethasone dipropionate,DB00394
,123827,DB00972,10037844,51,2453,44,1135,0.003556509,0.536383567,0.349007091,0.827307238,0.0155184,DB0097210037844_,4.165728839,-0.622905763,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,azelastine,DB00972
,123828,DB06282,10037844,55,1485,11,522,0.114081072,1.757208247,0.900970248,3.752208216,0.232271184,DB0628210037844_,1.459849692,0.563726327,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,levocetirizine,DB06282
,123832,DB00635,10040560,39,33014,26,23768,0.802432456,1.079920649,0.640773242,1.848107385,0.893152549,DB0063510040560_,0.112997885,0.076887565,NA,10040560,Shock,10047065,Vascular disorders,Vasc,prednisone,DB00635
,123860,DB00668,10068319,77,10014,16,4287,0.006220575,2.060146743,1.189906932,3.787722678,0.024364149,DB0066810068319_,3.714642515,0.722777215,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,123861,DB01611,10068319,84,11829,7,2354,0.022462004,2.387935759,1.10747264,6.128820036,0.067632109,DB0161110068319_,2.693672424,0.870429293,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxychloroquine,DB01611
,123864,DB00193,10060800,100,19220,31,8671,0.07206154,1.455310646,0.963254188,2.255454207,0.164886841,DB0019310060800_,1.802495853,0.37521938,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,tramadol,DB00193
,123865,DB00588,10060800,81,16443,26,8442,0.040184992,1.599441609,1.016289357,2.595027659,0.106061103,DB0058810060800_,2.243739905,0.469654574,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,fluticasone propionate,DB00588
,123866,DB00641,10060800,66,14058,45,12430,0.183523857,1.296803294,0.873806355,1.940105938,0.328336822,DB0064110060800_,1.113715303,0.259902231,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,simvastatin,DB00641
,123867,DB00678,10060800,61,15538,35,10689,0.407404801,1.198928224,0.778028068,1.873790276,0.576908316,DB0067810060800_,0.550071923,0.181428011,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,losartan,DB00678
,123880,DB00381,10013990,66,29294,53,22834,0.926364913,0.970658798,0.665620343,1.42142554,0.968710286,DB0038110013990_,0.031789695,-0.029780264,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,123881,DB00425,10013990,38,12657,16,7468,0.323334011,1.401296906,0.762325628,2.693842957,0.491759554,DB0042510013990_,0.709765394,0.337398169,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,zolpidem,DB00425
,123886,DB00175,10044565,108,8023,49,6057,0.003382485,1.663918396,1.174554072,2.386363316,0.014903799,DB0017510044565_,4.206139146,0.5091753,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,123901,DB00996,10002544,88,38865,14,22411,4.5049010560913e-07,3.624509195,2.04900856,6.903204172,7.05879727328524e-06,DB0099610002544_,11.86123588,1.287718885,female,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,123905,DB00537,10013573,218,7339,87,4211,0.004500715,1.437715302,1.112892821,1.870747168,0.018780964,DB0053710013573_,3.974911488,0.363055258,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,123911,DB00374,10005557,46,17670,20,5704,0.254232466,0.74246645,0.430093577,1.32620896,0.414855995,DB0037410005557_,0.879823819,-0.297777595,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,treprostinil,DB00374
,123913,DB00497,10042674,122,19145,74,16301,0.021471052,1.403724961,1.042277575,1.901446202,0.065380745,DB0049710042674_,2.727527479,0.33912939,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,123915,DB00190,10052904,32,3265,48,4626,0.820780735,0.944562055,0.582987242,1.511998276,0.904559154,DB0019010052904_,0.100307576,-0.057033893,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,carbidopa,DB00190
,123925,DB00153,10022004,56,7367,25,3414,1,1.038032192,0.635843261,1.739405488,1,DB0015310022004_,0,0.037326798,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,123926,DB00472,10022004,67,10692,14,4298,0.025800343,1.923703394,1.069253881,3.710447701,0.075246824,DB0047210022004_,2.586981579,0.654252179,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,123935,DB00927,10020937,99,7398,33,4983,0.00032435,2.020569123,1.347822313,3.099552621,0.002150197,DB0092710020937_,6.142195595,0.703379216,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,123941,DB01156,10022093,50,13572,7,6321,0.000927647,3.326396457,1.499897978,8.701588176,0.005177548,DB0115610022093_,5.263423702,1.201889573,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,123943,DB00051,10029331,129,25602,55,11365,0.872791472,1.041152896,0.753104791,1.456038206,0.944476074,DB0005110029331_,0.057124924,0.040328653,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,123945,DB00448,10029331,50,5095,50,3074,0.012670775,0.603400432,0.398377909,0.913942201,0.042991006,DB0044810029331_,3.146764348,-0.505174236,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,lansoprazole,DB00448
,123946,DB01156,10029331,86,13536,40,6288,1,0.998747023,0.67788583,1.493912202,1,DB0115610029331_,0,-0.001253762,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,123956,DB00207,10030124,67,9013,36,5419,0.611346883,1.118990451,0.734437489,1.730071109,0.753416922,DB0020710030124_,0.283136524,0.112426896,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,123957,DB00321,10030124,57,7390,14,2836,0.144478216,1.562458374,0.857886107,3.041246769,0.276310383,DB0032110030124_,1.28623047,0.446260461,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,123974,DB00813,10028596,30,10542,52,10116,0.010558463,0.553629318,0.340693105,0.88495301,0.037169918,DB0081310028596_,3.292255498,-0.591259917,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,fentanyl,DB00813
,123982,DB00451,10028116,43,47228,14,15405,1,1.001849711,0.537473374,1.983323625,1,DB0045110028116_,0,0.001848003,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,124008,DB00363,10054112,916,3712,1316,5572,0.361045314,1.044788416,0.949880935,1.148979425,0.530957903,DB0036310054112_,0.633072539,0.043814392,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,clozapine,DB00363
,124037,DB00158,10070863,63,16752,36,8068,0.451783523,0.842843215,0.550488993,1.308171984,0.61939964,DB0015810070863_,0.479004592,-0.170974323,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,124038,DB00341,10070863,76,11329,45,5023,0.137793299,0.748806247,0.510412153,1.109796476,0.266629628,DB0034110070863_,1.321894745,-0.289275011,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,124044,DB08932,10005619,103,19340,33,6564,0.843519434,1.059323923,0.70876513,1.620869797,0.92070296,DB0893210005619_,0.082617814,0.057630896,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,macitentan,DB08932
,124047,DB08932,10017412,125,19318,28,6569,0.049782796,1.517992381,1.000122085,2.378524997,0.124628866,DB0893210017412_,2.082415029,0.41738866,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,macitentan,DB08932
,124055,DB01611,10029354,31,11882,25,2336,7.30575637177872e-07,0.24381679,0.13905985,0.431589802,1.084925458939e-05,DB0161110029354_,11.43141418,-1.411338198,male,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,hydroxychloroquine,DB01611
,124062,DB01109,10001551,32,4380,44,4226,0.135089733,0.701734183,0.429815278,1.134369931,0.262800846,DB0110910001551_,1.336358775,-0.354200603,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,heparin,DB01109
,124071,DB01109,10006093,26,4386,62,4208,5.99696850310663e-05,0.402368242,0.243746513,0.647091531,0.000515553,DB0110910006093_,7.570270527,-0.910387584,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,heparin,DB01109
,124077,DB00019,10028391,71,18941,22,9507,0.047574616,1.61983016,0.991326538,2.746967797,0.120524194,DB0001910028391_,2.115904764,0.482321304,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pegfilgrastim,DB00019
,124078,DB00019,10028836,45,18967,7,9522,0.001725225,3.227229187,1.443962037,8.485194935,0.00860566,DB0001910028836_,4.755335123,1.171623932,female,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pegfilgrastim,DB00019
,124081,DB01254,10000087,32,3435,36,3112,0.394759559,0.805333717,0.482937541,1.337464593,0.564664267,DB0125410000087_,0.571523943,-0.216498533,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,dasatinib,DB01254
,124091,DB00338,10031009,105,33569,47,22225,0.025101749,1.479079878,1.038588927,2.134202862,0.073700025,DB0033810031009_,2.607752141,0.391420191,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,124103,DB00399,10037377,61,6931,65,4933,0.028871006,0.667967838,0.462211372,0.964220208,0.082204885,DB0039910037377_,2.498540556,-0.403515253,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zoledronic acid,DB00399
,124107,DB00451,10012218,80,47191,21,15398,0.419461851,1.243002318,0.760683861,2.117461407,0.588423413,DB0045110012218_,0.5303085,0.217529678,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,124111,DB00996,10012218,63,38890,128,22297,1.95178020655089e-17,0.282194383,0.205208125,0.384647636,1.5883140163836e-15,DB0099610012218_,34.07610331,-1.265159144,male,10012218,Delirium,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,124116,DB08875,10033425,24,619,30,1213,0.11027105,1.567343071,0.868721378,2.799911498,0.226425635,DB0887510033425_,1.485338709,0.449381874,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,cabozantinib,DB08875
,124120,DB00186,10043882,62,16839,32,9976,0.593379185,1.147861847,0.737066411,1.819093524,0.739420764,DB0018610043882_,0.30188815,0.137900948,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,lorazepam,DB00186
,124128,DB00541,10054889,20,3114,58,4239,0.002639928,0.469451946,0.266874721,0.794186663,0.012181254,DB0054110054889_,4.407857058,-0.756189338,NA,10054889,Transaminases increased,10022891,Investigations,Inv,vincristine,DB00541
,124130,DB00904,10054889,48,23021,58,14398,0.000885414,0.517593621,0.345384207,0.772563388,0.004985671,DB0090410054889_,5.301187203,-0.658564861,NA,10054889,Transaminases increased,10022891,Investigations,Inv,ondansetron,DB00904
,124131,DB00051,10069327,44,25687,22,11398,0.688950639,0.887462471,0.520326779,1.555508968,0.812484804,DB0005110069327_,0.207658068,-0.119389045,NA,10069327,Product quality issue,10077536,Product issues,Prod,adalimumab,DB00051
,124143,DB01611,10008531,94,11819,21,2340,0.614148143,0.886203187,0.546412339,1.501211431,0.755699924,DB0161110008531_,0.280110907,-0.120809024,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,124146,DB01268,10035528,61,2082,67,3063,0.121120589,1.339337241,0.926628786,1.932808013,0.243017799,DB0126810035528_,1.414620592,0.292174895,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,sunitinib,DB01268
,124147,DB00335,10047942,106,8360,51,5414,0.084687298,1.345979752,0.953200307,1.922065755,0.18624314,DB0033510047942_,1.680702257,0.297122188,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,atenolol,DB00335
,124154,DB00047,10008531,45,9240,44,8474,0.831700725,0.937975251,0.604397154,1.456370673,0.912067678,DB0004710008531_,0.092041083,-0.064031715,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,124155,DB00341,10008531,103,11302,45,5023,1,1.017269188,0.708848408,1.480387422,1,DB0034110008531_,0,0.01712177,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,124161,DB00341,10051792,85,11320,34,5034,0.690179547,1.111739,0.73762192,1.709598924,0.813113235,DB0034110051792_,0.206884899,0.105925456,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,124169,DB00678,10019196,54,15545,18,10706,0.007774634,2.066068101,1.192052206,3.745242916,0.029104423,DB0067810019196_,3.536865137,0.725647333,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,124170,DB06637,10019196,71,6091,11,2008,0.019623619,2.127815016,1.117412574,4.462870771,0.060894495,DB0663710019196_,2.798612505,0.755095639,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,dalfampridine,DB06637
,124172,DB00904,10028836,121,22948,42,14414,0.000672804,1.809542141,1.263375846,2.637406951,0.003964282,DB0090410028836_,5.530430484,0.593073853,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,124174,DB01076,10013774,65,25682,23,25560,8.43168279082839e-06,2.81277517,1.72387834,4.744275379,9.35726333784777e-05,DB0107610013774_,9.276772596,1.034171601,female,10013774,Dry eye,10015919,Eye disorders,Eye,atorvastatin,DB01076
,124178,DB00005,10013971,55,128027,13,42406,0.326453031,1.401319255,0.75573053,2.796617972,0.494974631,DB0000510013971_,0.703248768,0.337414118,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,124181,DB01104,10037400,42,15421,17,7269,0.6761497,1.164543624,0.648371538,2.18359076,0.803771561,DB0110410037400_,0.218440179,0.152329271,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,124203,DB00331,10031009,52,24894,24,20728,0.015454974,1.804049015,1.091917037,3.061519842,0.050463031,DB0033110031009_,2.986514274,0.590033591,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,124204,DB01076,10031009,53,25694,28,25555,0.007253805,1.882583525,1.169031045,3.092174249,0.027533035,DB0107610031009_,3.592368737,0.632645049,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,124217,DB08934,10012174,28,4461,32,6172,0.512435232,1.210574585,0.701181463,2.078965227,0.672627219,DB0893410012174_,0.396564012,0.19109511,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,sofosbuvir,DB08934
,124223,DB00115,10017413,195,18230,112,10360,0.952421105,0.98943798,0.779268207,1.261382583,0.99044108,DB0011510017413_,0.0096049,-0.010618194,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,124224,DB00169,10017413,266,38425,124,18051,1,1.007739165,0.810673949,1.258348179,1,DB0016910017413_,0,0.007709371,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,124225,DB00421,10017413,37,8866,32,5220,0.133198153,0.680805153,0.412106695,1.130322922,0.260196813,DB0042110017413_,1.346316963,-0.384479132,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,spironolactone,DB00421
,124229,DB01136,10017413,100,9784,89,11026,0.107875661,1.266207689,0.940725272,1.706528165,0.222873786,DB0113610017413_,1.501149652,0.236026362,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,carvedilol,DB01136
,124232,DB00115,10061822,140,18285,63,10409,0.124510489,1.2650492,0.932172305,1.733164831,0.24782358,DB0011510061822_,1.395038157,0.235111015,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,124246,DB01076,10019196,92,25655,66,25517,0.046209575,1.38642702,0.999199019,1.932838691,0.117895529,DB0107610019196_,2.137956393,0.326729949,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,124247,DB00588,10042674,149,16375,46,8422,0.002289618,1.665920118,1.188321878,2.374576726,0.010862308,DB0058810042674_,4.522456451,0.510377594,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,124249,DB00215,10047571,74,11029,14,5262,0.000800097,2.521725324,1.410749913,4.840542266,0.00457584,DB0021510047571_,5.386964954,0.92494332,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,citalopram,DB00215
,124257,DB00331,10017626,46,24900,26,20726,0.124045257,1.472638347,0.891063024,2.482564966,0.247150244,DB0033110017626_,1.397758854,0.387055586,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,metformin,DB00331
,124259,DB00331,10017918,40,24906,27,20725,0.46174248,1.232776828,0.737731152,2.089783246,0.628950523,DB0033110017918_,0.463702685,0.209269209,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,metformin,DB00331
,124263,DB00331,10024574,33,24913,27,20725,1,1.016761481,0.592683749,1.758604934,1,DB0033110024574_,0,0.016622558,NA,10024574,Lipase increased,10022891,Investigations,Inv,metformin,DB00331
,124273,DB00338,10041541,36,33638,25,22247,0.896125082,0.952387477,0.555920909,1.655615489,0.956301489,DB0033810041541_,0.044682051,-0.048783314,NA,10041541,Spinal compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,124283,DB01590,10021097,24,4714,37,2830,0.000290768,0.389458064,0.222397273,0.670186051,0.001966509,DB0159010021097_,6.231495348,-0.942999084,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,everolimus,DB01590
,124285,DB00338,10031127,39,33635,49,22223,0.003059632,0.525893456,0.33613441,0.817807714,0.013745076,DB0033810031127_,4.287074654,-0.642656643,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,omeprazole,DB00338
,124290,DB00153,10051055,27,7396,34,3405,0.000138318,0.365636147,0.211813412,0.625451013,0.001051841,DB0015310051055_,6.85721299,-1.006116573,male,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,ergocalciferol,DB00153
,124292,DB01097,10003246,60,6205,20,1483,0.200879392,0.717036817,0.4245135,1.260064238,0.350024184,DB0109710003246_,1.049753029,-0.33262809,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,124293,DB00051,10013082,72,25659,25,11395,0.322256226,1.278949542,0.801029211,2.105687104,0.49060293,DB0005110013082_,0.712120175,0.24603907,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,124295,DB01097,10022061,121,6144,6,1497,2.30206021232675e-06,4.913076403,2.186636364,13.67961647,2.99478607676361e-05,DB0109710022061_,10.41605266,1.591900304,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,124296,DB01097,10022095,111,6154,12,1491,0.005430361,2.240873043,1.228768367,4.479900357,0.021846949,DB0109710022095_,3.823693993,0.806865541,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,124298,DB00051,10022112,83,25648,19,11401,0.00704393,1.941811959,1.168204184,3.387893882,0.026924943,DB0005110022112_,3.614702161,0.663621536,NA,10022112,Injection site warmth,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,124302,DB00874,10002034,45,3290,34,1942,0.292366065,0.781295816,0.487528134,1.262461386,0.45794786,DB0087410002034_,0.780999944,-0.246801435,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,guaifenesin,DB00874
,124303,DB01222,10002034,119,9155,80,5325,0.336246164,0.865217105,0.644909618,1.165903974,0.505303117,DB0122210002034_,0.682596798,-0.144774816,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,budesonide,DB01222
,124305,DB01222,10003658,87,9187,76,5329,0.011148512,0.664061492,0.481547984,0.917338502,0.038820778,DB0122210003658_,3.248799672,-0.409380525,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,budesonide,DB01222
,124364,DB00959,10009033,52,8026,34,4968,0.824268947,0.946696392,0.601858248,1.506698104,0.906902857,DB0095910009033_,0.097719938,-0.054776837,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,124366,DB11089,10009033,67,10108,58,8349,0.856998544,0.954127781,0.660439511,1.382051339,0.931393055,DB1108910009033_,0.071073905,-0.046957674,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,124367,DB00760,10012735,28,752,33,982,0.695727562,1.107930071,0.638877131,1.909303669,0.816830399,DB0076010012735_,0.202323795,0.102493474,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,meropenem,DB00760
,124368,DB00193,10017918,46,19274,12,8690,0.090168549,1.728291225,0.90041186,3.585771411,0.195486664,DB0019310017918_,1.632263116,0.547133189,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,tramadol,DB00193
,124373,DB00316,10017918,155,65319,45,36908,4.49824131963603e-05,1.94624347,1.388111213,2.777071023,0.000403881,DB0031610017918_,7.814389345,0.665901089,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,124375,DB00381,10017918,47,29313,25,22862,0.124080341,1.466250049,0.884023435,2.48666869,0.247201407,DB0038110017918_,1.397551862,0.382708154,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,amlodipine,DB00381
,124377,DB00480,10017918,100,67328,67,67595,0.010516105,1.498443769,1.08854063,2.073856151,0.037058025,DB0048010017918_,3.295270345,0.404427082,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,124382,DB00695,10017918,72,27977,26,20502,0.001433135,2.029294737,1.27933574,3.312629047,0.00740514,DB0069510017918_,4.905580965,0.707688313,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,furosemide,DB00695
,124384,DB00761,10017918,42,15265,11,8614,0.021379236,2.154527028,1.089428744,4.643031675,0.065184226,DB0076110017918_,2.730537766,0.767571223,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,124390,DB00996,10017918,85,38868,20,22405,0.000147162,2.449826892,1.491133839,4.212625716,0.001108356,DB0099610017918_,6.804877188,0.896017366,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,gabapentin,DB00996
,124394,DB01234,10017918,41,31584,27,32861,0.068845133,1.579893098,0.948523602,2.67155136,0.159246212,DB0123410017918_,1.837303773,0.457357185,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,124414,DB01234,10020646,33,31592,50,32838,0.099609078,0.686037413,0.428058588,1.086425292,0.210170636,DB0123410020646_,1.559835527,-0.376823115,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,124417,DB00207,10035528,30,9050,50,5405,7.15816844167241e-06,0.358368134,0.219725416,0.575491326,8.09954616828926e-05,DB0020710035528_,9.421117433,-1.026194515,male,10035528,Platelet count decreased,10022891,Investigations,Inv,azithromycin,DB00207
,124419,DB00281,10035528,78,11380,35,5636,0.688763019,1.103700861,0.730762622,1.697182989,0.812391113,DB0028110035528_,0.207773389,0.098668952,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,lidocaine,DB00281
,124421,DB00588,10035528,93,16431,75,8393,0.004072699,0.633388913,0.461690581,0.87144544,0.017340391,DB0058810035528_,4.054716742,-0.456670649,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,124424,DB00956,10035528,36,5778,24,3443,0.689116435,0.893834864,0.517762492,1.568930647,0.81249806,DB0095610035528_,0.207641753,-0.112234236,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,hydrocodone,DB00956
,124425,DB00959,10035528,54,8024,38,4964,0.590633924,0.87913769,0.568944863,1.370646528,0.737205598,DB0095910035528_,0.304888459,-0.12881375,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,methylprednisolone,DB00959
,124426,DB01222,10035528,49,9225,41,5364,0.099608949,0.694962588,0.448896331,1.080731758,0.210170636,DB0122210035528_,1.559835527,-0.363897265,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,budesonide,DB01222
,124427,DB01409,10035528,32,5999,26,3940,0.422539951,0.808364993,0.465936378,1.414616624,0.591524426,DB0140910035528_,0.525052302,-0.212741598,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,tiotropium,DB01409
,124442,DB00956,10042772,31,5783,27,3440,0.172861547,0.683025745,0.393724332,1.191574558,0.314614719,DB0095610042772_,1.156406503,-0.381222726,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,124444,DB00207,10046306,106,8974,47,5408,0.09289333,1.359094894,0.953608206,1.962546814,0.199901852,DB0020710046306_,1.609928771,0.306818959,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,azithromycin,DB00207
,124446,DB00321,10046306,66,7381,13,2837,0.023208634,1.95129794,1.064249496,3.862528776,0.069373851,DB0032110046306_,2.668245274,0.668494761,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,amitriptyline,DB00321
,124447,DB00381,10046306,170,29190,77,22810,6.18577268280821e-05,1.725212459,1.309708055,2.290029135,0.000529102,DB0038110046306_,7.544329387,0.545350208,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,124448,DB00425,10046306,95,12600,34,7450,0.013224308,1.652038308,1.104631064,2.524360855,0.044478685,DB0042510046306_,3.112745193,0.502009864,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,zolpidem,DB00425
,124450,DB00588,10046306,268,16256,93,8375,0.000928678,1.484624102,1.166585031,1.903251519,0.005182102,DB0058810046306_,5.26254453,0.395161611,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,124453,DB00761,10046306,129,15178,45,8580,0.005383978,1.620472397,1.144612612,2.331265463,0.021701864,DB0076110046306_,3.830357128,0.48271771,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,124454,DB00787,10046306,121,16879,72,17176,0.000289472,1.710088406,1.26594464,2.324409155,0.001959002,DB0078710046306_,6.235319974,0.536545068,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,acyclovir,DB00787
,124455,DB00813,10046306,47,10525,12,10156,9.71799759377752e-06,3.778894586,1.972453859,7.831968052,0.000106035,DB0081310046306_,9.151744259,1.329431529,female,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,fentanyl,DB00813
,124456,DB00874,10046306,76,3259,35,1941,0.234165643,1.293179335,0.851997436,1.997407321,0.391032301,DB0087410046306_,0.938965112,0.257103787,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,guaifenesin,DB00874
,124458,DB00959,10046306,90,7988,30,4972,0.002443376,1.867216254,1.22090708,2.929313142,0.011454277,DB0095910046306_,4.469392084,0.624448688,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,124459,DB01136,10046306,66,9818,36,11079,0.000444722,2.0687134,1.356781562,3.199994258,0.002802232,DB0113610046306_,5.877339135,0.726926868,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,carvedilol,DB01136
,124523,DB00316,10058151,30,65444,26,36927,0.125210024,0.651034233,0.372131205,1.14624436,0.2488767,DB0031610058151_,1.390797685,-0.429193054,NA,10058151,Pulseless electrical activity,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,124535,DB00480,10018276,83,67345,40,67622,9.34385733046669e-05,2.083512629,1.412090428,3.119738971,0.00075307,DB0048010018276_,7.191351976,0.734055233,NA,10018276,Gingival bleeding,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,124542,DB00878,10003549,30,1156,26,894,0.684255369,0.892383993,0.506071383,1.583134264,0.809198586,DB0087810003549_,0.211710922,-0.113858754,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,chlorhexidine,DB00878
,124543,DB00820,10006784,44,11871,11,5805,0.044185679,1.955962176,0.993084225,4.20271286,0.113963248,DB0082010006784_,2.171879272,0.670882234,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,124549,DB01240,10020937,65,5686,11,1565,0.16002093,1.626280011,0.849023659,3.426082522,0.297485687,DB0124010020937_,1.212389165,0.486295205,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,epoprostenol,DB01240
,124554,DB00878,10037844,38,1148,29,891,1,1.016994151,0.605528101,1.724320515,1,DB0087810037844_,0,0.016851366,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,chlorhexidine,DB00878
,124555,DB00682,10037867,31,19428,21,16343,0.487823427,1.241775515,0.690783981,2.274639823,0.651528352,DB0068210037867_,0.428434365,0.216542222,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,124558,DB01240,10037867,39,5712,13,1563,0.501960503,0.820926775,0.427686845,1.68043808,0.663333341,DB0124010037867_,0.410477638,-0.197321363,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,epoprostenol,DB01240
,124559,DB00820,10042209,58,11857,10,5806,0.001060148,2.839941355,1.43778959,6.237204272,0.005784328,DB0082010042209_,5.152603133,1.043783402,female,10042209,Stress,10037175,Psychiatric disorders,Psych,tadalafil,DB00820
,124564,DB01240,10047513,63,5688,7,1569,0.018391643,2.482425656,1.133758693,6.438654295,0.057829336,DB0124010047513_,2.850259092,0.909236169,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,epoprostenol,DB01240
,124582,DB00437,10020993,18,6903,52,11494,0.047268261,0.576387842,0.31704624,1.002673437,0.11996198,DB0043710020993_,2.120580416,-0.550974508,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,allopurinol,DB00437
,124593,DB01248,10021143,17,2683,37,1337,2.35120326361496e-07,0.2290495,0.120457374,0.418882374,3.92638994816513e-06,DB0124810021143_,12.44779014,-1.473817143,male,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docetaxel,DB01248
,124594,DB13867,10021143,40,4510,21,2533,0.893671065,1.069788195,0.614351338,1.914237303,0.955733567,DB1386710021143_,0.0452761,0.06746068,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,124596,DB00381,10035742,31,29329,43,22844,0.01386624,0.561539698,0.341945457,0.912392527,0.046200295,DB0038110035742_,3.074769096,-0.577072808,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,124598,DB00441,10035742,20,2254,39,1855,0.001464889,0.422125415,0.232430544,0.744547748,0.00754253,DB0044110035742_,4.887197639,-0.862452818,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gemcitabine,DB00441
,124608,DB00321,10074903,66,7381,25,2825,1,1.010433541,0.627512686,1.674862675,1,DB0032110074903_,0,0.010379487,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,amitriptyline,DB00321
,124617,DB00788,10006002,47,9309,14,5047,0.058790238,1.820051401,0.98393794,3.58340892,0.141226596,DB0078810006002_,1.957389618,0.598864743,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,124618,DB06724,10006002,61,7868,12,3907,0.001719922,2.524056009,1.343590466,5.156317613,0.008587357,DB0672410006002_,4.757464324,0.925867135,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,124619,DB14500,10006002,42,7767,16,4057,0.332398607,1.371102959,0.75375294,2.615831447,0.501339687,DB1450010006002_,0.690471389,0.315615495,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,124649,DB00480,10045285,46,67382,30,67632,0.067030305,1.539008767,0.950780232,2.525612111,0.156023162,DB0048010045285_,1.857750807,0.431138552,NA,10045285,Ulcer,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,124650,DB00115,10055798,63,18362,46,10426,0.195760646,0.777666761,0.522929534,1.164166746,0.343978113,DB0011510055798_,1.067177249,-0.251457174,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,cyanocobalamin,DB00115
,124669,DB08895,10025197,70,28044,9,6637,0.085899632,1.8406702,0.915623657,4.194307604,0.188195193,DB0889510025197_,1.670275595,0.610129745,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,tofacitinib,DB08895
,124691,DB00814,10039101,60,8227,17,3398,0.207996159,1.457762659,0.83788229,2.668896804,0.358821189,DB0081410039101_,1.024931095,0.376902835,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,meloxicam,DB00814
,124692,DB00924,10039101,64,10098,19,4232,0.226978651,1.41170656,0.833778385,2.498336603,0.382127407,DB0092410039101_,0.962001199,0.344799299,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,124693,DB00950,10039101,42,4676,12,2044,0.234609126,1.529863348,0.788687753,3.199226978,0.391449575,DB0095010039101_,0.937898573,0.425178416,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fexofenadine,DB00950
,124698,DB13961,10039101,67,9390,23,6391,0.003551387,1.982582393,1.21695143,3.340469556,0.015499909,DB1396110039101_,4.166921137,0.684400234,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,124718,DB00193,10068319,110,19210,18,8684,1.27653589912372e-05,2.762484611,1.667804351,4.837032382,0.000134538,DB0019310068319_,8.913664798,1.016130496,female,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,124720,DB00814,10068319,75,8212,18,3397,0.038857231,1.723524772,1.018095047,3.069340524,0.103350601,DB0081410068319_,2.269628178,0.54437148,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,meloxicam,DB00814
,124721,DB00950,10068319,51,4667,20,2036,0.795447251,1.112428945,0.649698611,1.975293129,0.889265654,DB0095010068319_,0.117359265,0.106545864,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fexofenadine,DB00950
,124742,DB06403,10015090,265,21206,78,6583,0.749319438,1.054639265,0.815089241,1.377835206,0.857883319,DB0640310015090_,0.153287181,0.053198779,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,124743,DB06403,10020772,101,21370,29,6632,0.757441857,1.080841626,0.708385021,1.696377711,0.86438411,DB0640310020772_,0.145738037,0.077740021,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ambrisentan,DB06403
,124746,DB00181,10061296,35,9821,15,5856,0.308705744,1.391276278,0.739641161,2.74441674,0.476034641,DB0018110061296_,0.742264653,0.330221512,NA,10061296,Motor dysfunction,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,124752,DB00316,10057840,30,65444,27,36926,0.096784638,0.626904713,0.360155302,1.096217617,0.205957271,DB0031610057840_,1.580086556,-0.466960723,NA,10057840,Major depression,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,124762,DB00535,10047700,35,1169,15,631,0.548181675,1.259363478,0.66414469,2.501868371,0.70266837,DB0053510047700_,0.352870233,0.230606417,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cefdinir,DB00535
,124788,DB01039,10011906,56,2917,119,2932,3.37750173523982e-06,0.473067221,0.336578346,0.658180192,4.19058924289727e-05,DB0103910011906_,10.08008411,-0.748517785,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,124795,DB00343,10007625,38,8698,25,5070,0.694840039,0.886007892,0.520399433,1.533332593,0.816298847,DB0034310007625_,0.202974756,-0.121029421,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,diltiazem,DB00343
,124796,DB01076,10007625,29,25718,47,25536,0.038844116,0.61266433,0.371716662,0.994171309,0.103323224,DB0107610007625_,2.269893107,-0.489938078,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,124839,DB08895,10037377,91,28023,40,6606,0.001674136,0.53632078,0.365539576,0.799364849,0.008406663,DB0889510037377_,4.77873068,-0.623022826,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,124842,DB01240,10027175,57,5694,14,1562,0.884500285,1.116873027,0.612454293,2.176310685,0.951918915,DB0124010027175_,0.049275421,0.11053284,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,epoprostenol,DB01240
,124845,DB08931,10016173,353,6224,123,2323,0.560127905,1.071138603,0.864951468,1.333534766,0.712766268,DB0893110016173_,0.338601727,0.068722198,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,riociguat,DB08931
,124849,DB06228,10005750,38,15874,50,16026,0.240690313,0.767285768,0.489309571,1.194381333,0.398685753,DB0622810005750_,0.919581758,-0.264895968,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,rivaroxaban,DB06228
,124855,DB00497,10002198,48,19219,30,16345,0.211052315,1.360722774,0.844315545,2.225332574,0.36257051,DB0049710002198_,1.014536313,0.30801601,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,oxycodone,DB00497
,124860,DB00005,10047482,223,127859,62,42357,0.243725104,1.191530388,0.895389472,1.605893045,0.402116208,DB0000510047482_,0.911014158,0.175238521,NA,10047482,Viral upper respiratory tract infection,10021881,Infections and infestations,Infec,etanercept,DB00005
,124863,DB00451,10047482,51,47220,8,15411,0.049439255,2.08044136,0.979828195,5.077380589,0.123963638,DB0045110047482_,2.087766998,0.732580064,NA,10047482,Viral upper respiratory tract infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,124896,DB00921,10038743,33,5812,26,4877,0.895934179,1.065056152,0.616814658,1.85704705,0.956271898,DB0092110038743_,0.044712994,0.063027522,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,124905,DB00318,10011906,83,4200,114,1725,1.89606049002952e-16,0.29909753,0.221367353,0.402716647,1.3752620586947e-14,DB0031810011906_,31.917547,-1.206985573,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,codeine,DB00318
,124906,DB00108,10002948,53,10141,10,3285,0.140627594,1.716715772,0.86311362,3.789032699,0.270718932,DB0010810002948_,1.306674147,0.540413031,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,124913,DB01015,10040829,43,9844,27,9354,0.094518354,1.513280391,0.91318461,2.549049816,0.202511674,DB0101510040829_,1.596957744,0.414279739,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,124915,DB00454,10037844,72,1895,13,588,0.089261175,1.718135688,0.935695019,3.406856192,0.194071714,DB0045410037844_,1.639527531,0.541239801,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,meperidine,DB00454
,124919,DB00005,10037377,81,128001,50,42369,0.000776959,0.536251298,0.37228683,0.779045501,0.004463488,DB0000510037377_,5.411824707,-0.623152388,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,124945,DB00213,10025197,34,18861,25,13396,0.895573014,0.965920889,0.559256899,1.689696114,0.95615204,DB0021310025197_,0.044838341,-0.034673344,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,pantoprazole,DB00213
,124956,DB01255,10028813,91,2042,39,1539,0.003701595,1.75830625,1.188144147,2.64461815,0.016026423,DB0125510028813_,4.133516453,0.564350988,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lisdexamfetamine,DB01255
,124958,DB00768,10013709,96,1819,34,650,1,1.008956107,0.668151823,1.555378682,1,DB0076810013709_,0,0.008916239,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,olopatadine,DB00768
,124965,DB00264,10033318,139,29468,88,24804,0.038410697,1.329536575,1.010157889,1.757775106,0.102474009,DB0026410033318_,2.278146084,0.284830442,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,metoprolol,DB00264
,124967,DB00381,10033318,177,29183,74,22813,3.80906173960507e-06,1.869757849,1.416893893,2.488403496,4.65247155323044e-05,DB0038110033318_,9.97552687,0.62580893,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,amlodipine,DB00381
,124968,DB00472,10033318,38,10721,12,4300,0.5334437,1.270053367,0.648937705,2.672396121,0.690188759,DB0047210033318_,0.370790155,0.239058921,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,fluoxetine,DB00472
,124990,DB00381,10019075,34,29326,36,22851,0.228029532,0.735928733,0.446582256,1.210381649,0.383428623,DB0038110019075_,0.958601795,-0.306621995,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,124993,DB01255,10041349,72,2061,50,1528,0.780245676,1.067594323,0.729163669,1.573520614,0.880389357,DB0125510041349_,0.127391019,0.065407821,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,lisdexamfetamine,DB01255
,125005,DB01261,10019211,179,3602,75,3228,1.88387883957897e-08,2.138548422,1.617192659,2.851438911,3.96459209754469e-07,DB0126110019211_,14.74069268,0.760127291,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sitagliptin,DB01261
,125007,DB00190,10025482,93,3204,97,4577,0.036605505,1.369541559,1.015458886,1.846219853,0.098786005,DB0019010025482_,2.314799336,0.314476055,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,125008,DB00268,10025482,118,2857,29,1516,0.000127651,2.158779686,1.420228577,3.378613433,0.000982663,DB0026810025482_,6.925243999,0.769543102,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,125013,DB01307,10020993,50,2474,51,2018,0.268076693,0.799732491,0.527942695,1.210890452,0.430511432,DB0130710020993_,0.842781399,-0.223477993,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,insulin detemir,DB01307
,125021,DB00264,10028035,30,29577,28,24864,0.694766252,0.900702252,0.519853444,1.564989091,0.816266888,DB0026410028035_,0.203013909,-0.10458054,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,125047,DB01039,10020937,37,2936,23,3028,0.068517439,1.658955229,0.957337249,2.932109081,0.158634801,DB0103910020937_,1.84115057,0.506188024,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,fenofibrate,DB01039
,125048,DB00331,10028836,100,24846,60,20692,0.046736416,1.388004601,0.997351528,1.945932027,0.118956781,DB0033110028836_,2.128995033,0.327867177,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,125050,DB01069,10028836,62,6638,7,2388,0.001393287,3.18621713,1.455017977,8.262564288,0.007231226,DB0106910028836_,4.929346649,1.158834361,female,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,promethazine,DB01069
,125051,DB00381,10046543,67,29293,24,22863,0.000670614,2.17881736,1.348305785,3.633977122,0.003954477,DB0038110046543_,5.532907001,0.778782234,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,125065,DB00451,10062352,112,47159,14,15405,0.000247401,2.613375275,1.493662981,4.935644865,0.001720123,DB0045110062352_,6.36535934,0.960642595,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,125066,DB00695,10062352,75,27974,27,20501,0.001221826,2.035676711,1.29500179,3.289455457,0.006489985,DB0069510062352_,5.037495131,0.7108283,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,125073,DB01062,10011224,68,4418,25,1720,0.907461468,1.05893074,0.658175948,1.754559281,0.958745315,DB0106210011224_,0.042129813,0.057259663,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxybutynin,DB01062
,125074,DB01118,10011224,75,2988,106,4603,0.590442579,1.089959739,0.796887987,1.484547017,0.737001765,DB0111810011224_,0.305164991,0.086140759,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,125085,DB00695,10037833,45,28004,28,20500,0.554110155,1.176468185,0.717846832,1.959132084,0.707663942,DB0069510037833_,0.345785956,0.162516886,NA,10037833,Rales,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,125088,DB01062,10042772,35,4451,17,1728,0.440976685,0.799298322,0.434613606,1.525758991,0.609206747,DB0106210042772_,0.495597583,-0.224021034,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,125090,DB01118,10047924,18,3045,39,4670,0.276409399,0.70787426,0.38040887,1.269991689,0.439848713,DB0111810047924_,0.821324445,-0.3454888,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,125096,DB00695,10051076,37,28012,18,20510,0.172747112,1.505035437,0.835153508,2.809050366,0.314473564,DB0069510051076_,1.156855265,0.408816444,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,125104,DB00264,10034474,70,29537,91,24801,0.006887826,0.645904096,0.465862696,0.892262077,0.026461049,DB0026410034474_,3.632081481,-0.437104245,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,metoprolol,DB00264
,125105,DB00338,10034474,84,33590,43,22229,0.174814669,1.29276173,0.884546961,1.913759954,0.317217394,DB0033810034474_,1.148167955,0.256780806,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,omeprazole,DB00338
,125106,DB00381,10034474,88,29272,62,22825,0.564831177,1.10678252,0.790280314,1.558122255,0.716495559,DB0038110034474_,0.33338323,0.101457176,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,amlodipine,DB00381
,125108,DB00331,10010071,43,24903,84,20668,2.73477041678509e-06,0.424855982,0.286949755,0.62100161,3.49203013870274e-05,DB0033110010071_,10.2624422,-0.856005035,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,metformin,DB00331
,125111,DB00999,10029354,137,21293,60,12179,0.087787199,1.305995443,0.956580838,1.801273481,0.191492659,DB0099910029354_,1.652905807,0.266965542,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,hydrochlorothiazide,DB00999
,125124,DB00005,10037423,38,128044,18,42401,0.216766761,0.699083585,0.389253986,1.301376676,0.369585464,DB0000510037423_,0.99537327,-0.357984966,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,125143,DB00374,10013700,77,17639,14,5710,0.049680181,1.78031583,0.998551786,3.410873369,0.124419375,DB0037410013700_,2.084097364,0.576790781,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,treprostinil,DB00374
,125166,DB00904,10007559,181,22888,112,14344,0.951979839,1.012798351,0.794987137,1.294856026,0.990021368,DB0090410007559_,0.010028752,0.012717144,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,ondansetron,DB00904
,125167,DB06724,10007559,62,7867,40,3879,0.204542106,0.764307972,0.504438772,1.169723298,0.354561233,DB0672410007559_,1.036874217,-0.268784466,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,calcium carbonate,DB06724
,125179,DB00996,10042609,156,38797,56,22369,0.002062527,1.606133592,1.175852854,2.221479152,0.009972137,DB0099610042609_,4.607960393,0.473829795,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,gabapentin,DB00996
,125194,DB00515,10051398,36,1834,27,2124,0.098144395,1.543982164,0.907661811,2.655508752,0.208050763,DB0051510051398_,1.569973176,0.4343649,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cisplatin,DB00515
,125216,DB06637,10023547,435,5727,150,1869,0.584165007,0.946414301,0.778359323,1.155616404,0.732021267,DB0663710023547_,0.311945712,-0.055074855,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,dalfampridine,DB06637
,125234,DB00316,10021328,34,65440,40,36913,0.002218171,0.479456899,0.2943454,0.777003666,0.010586993,DB0031610021328_,4.548129143,-0.735101277,NA,10021328,Ileus,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,125244,DB01222,10021789,105,9169,59,5346,0.870809933,1.037633851,0.745846129,1.455382866,0.942816974,DB0122210021789_,0.058883105,0.036942978,NA,10021789,Infection,10021881,Infections and infestations,Infec,budesonide,DB01222
,125247,DB00213,10033647,35,18860,38,13383,0.074598799,0.653599138,0.400682247,1.063350681,0.16917557,DB0021310033647_,1.776818227,-0.425261055,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,125248,DB00316,10033647,70,65404,42,36911,0.768176168,0.940590948,0.632495183,1.414000965,0.872806717,DB0031610033647_,0.136041149,-0.061246933,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,125255,DB00653,10040047,36,1056,53,769,0.001399242,0.494817675,0.311417501,0.778532274,0.007254971,DB0065310040047_,4.926068374,-0.703565917,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,magnesium sulfate,DB00653
,125278,DB01190,10010264,70,4864,39,2246,0.351673425,0.828838949,0.550540076,1.263806075,0.521406565,DB0119010010264_,0.651225186,-0.187729414,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,clindamycin,DB01190
,125284,DB00999,10038428,75,21355,44,12195,0.924007642,0.97338216,0.661678585,1.447260293,0.967014687,DB0099910038428_,0.033541596,-0.026978509,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,hydrochlorothiazide,DB00999
,125295,DB00222,10020937,29,3177,31,3097,0.795652043,0.911950015,0.528882885,1.568228906,0.889358676,DB0022210020937_,0.117254664,-0.092170098,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,glimepiride,DB00222
,125297,DB00047,10028411,65,9220,43,8475,0.100765919,1.389455142,0.929720864,2.095260969,0.212018519,DB0004710028411_,1.551081654,0.328911686,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin glargine,DB00047
,125300,DB00222,10033775,31,3175,19,3109,0.118863891,1.597537971,0.872291392,2.999891568,0.239532133,DB0022210033775_,1.429067706,0.468463676,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,glimepiride,DB00222
,125302,DB00588,10033775,171,16353,57,8411,0.003924203,1.542994604,1.135685948,2.123285279,0.016811618,DB0058810033775_,4.085685089,0.433725076,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,125303,DB00158,10040808,37,16778,34,8070,0.007415424,0.523420349,0.319354991,0.860390081,0.028035157,DB0015810040808_,3.574295959,-0.647370411,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,folic acid,DB00158
,125310,DB00996,10040808,37,38916,45,22380,0.000790302,0.472845092,0.297522426,0.74736379,0.004528685,DB0099610040808_,5.39732357,-0.748987444,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,gabapentin,DB00996
,125316,DB00364,10013700,85,2665,19,1381,0.000491607,2.317857654,1.390203645,4.055231745,0.003050853,DB0036410013700_,5.792334217,0.840643334,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,sucralfate,DB00364
,125318,DB00188,10001480,40,7846,41,8787,0.738325028,1.092610761,0.688036976,1.733821493,0.849334706,DB0018810001480_,0.163301934,0.088570025,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,125320,DB00641,10001480,32,14092,49,12426,0.018650936,0.575872298,0.356670402,0.918106176,0.05848024,DB0064110001480_,2.839066352,-0.551869348,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,125322,DB01234,10001480,133,31492,130,32758,0.621565432,1.064234825,0.828925253,1.366522423,0.761848794,DB0123410001480_,0.272007176,0.062256067,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,125323,DB00188,10013911,50,7836,60,8768,0.77399,0.932429892,0.626756407,1.382031646,0.876665036,DB0018810013911_,0.131630303,-0.069961313,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,125325,DB01234,10013911,182,31443,168,32720,0.283643184,1.127328153,0.908476074,1.39960342,0.448037084,DB0123410013911_,0.802879274,0.119850367,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,125327,DB00641,10016807,121,14003,53,12422,1.19047555535117e-05,2.02515109,1.453361731,2.855178806,0.000126436,DB0064110016807_,8.975774224,0.70564431,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,simvastatin,DB00641
,125329,DB00480,10041466,61,67367,46,67616,0.147778222,1.330981148,0.89277051,1.99641497,0.280894571,DB0048010041466_,1.269775874,0.285916376,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,125330,DB00682,10041466,44,19415,26,16338,0.186128049,1.424084433,0.857254828,2.410341309,0.331607925,DB0068210041466_,1.103801958,0.353529104,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,125332,DB00188,10044565,80,7806,58,8770,0.01277858,1.549592826,1.089799663,2.214956648,0.043284147,DB0018810044565_,3.139968837,0.437992203,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,125333,DB00531,10044565,45,7207,46,6470,0.598701877,0.87823142,0.568309244,1.356405661,0.743533137,DB0053110044565_,0.296341945,-0.129845144,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,125334,DB00188,10047899,130,7756,106,8722,0.015069783,1.379127735,1.056838347,1.802969661,0.049504374,DB0018810047899_,3.005694244,0.321451223,NA,10047899,Weight increased,10022891,Investigations,Inv,bortezomib,DB00188
,125336,DB01118,10061428,45,3018,74,4635,0.777006,0.933922543,0.628119113,1.375214314,0.878512755,DB0111810061428_,0.129524852,-0.068361775,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,amiodarone,DB01118
,125387,DB00213,10020635,39,18856,42,13379,0.07034707,0.65887703,0.414714148,1.044540796,0.161901123,DB0021310020635_,1.82076948,-0.417218363,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,125390,DB00761,10020635,46,15261,39,8586,0.069595923,0.663634209,0.423296006,1.045017118,0.160587177,DB0076110020635_,1.828918324,-0.410024171,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,125396,DB09153,10020635,27,7772,42,5657,0.002078575,0.467937573,0.27706158,0.777990979,0.01003957,DB0915310020635_,4.601220952,-0.759420384,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,sodium chloride,DB09153
,125403,DB00316,10051077,48,65426,25,36928,0.808016639,1.083701568,0.654953112,1.834348429,0.896432542,DB0031610051077_,0.109332235,0.080382559,NA,10051077,Post procedural haemorrhage,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,125416,DB00695,10051077,22,28027,30,20498,0.034078559,0.536353557,0.294701154,0.961748353,0.09357586,DB0069510051077_,2.368982838,-0.622961714,NA,10051077,Post procedural haemorrhage,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,125447,DB00213,10061273,33,18862,18,13403,0.396503677,1.302722738,0.712171747,2.458379448,0.566064641,DB0021310061273_,0.569047,0.264456488,NA,10061273,Malnutrition,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,125458,DB00695,10061273,39,28010,14,20514,0.025059053,2.040162011,1.083300553,4.069114536,0.073582887,DB0069510061273_,2.609342788,0.713029222,NA,10061273,Malnutrition,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,125484,DB01075,10009866,32,19916,20,11077,0.666910298,0.889904381,0.49331472,1.642562637,0.797567549,DB0107510009866_,0.226188746,-0.116641259,NA,10009866,Cold sweat,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,125485,DB00668,10000087,55,10036,22,4281,0.900807136,1.0664056,0.638767721,1.838920338,0.956764412,DB0066810000087_,0.044198092,0.064293741,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,epinephrine,DB00668
,125486,DB01109,10000087,38,4374,18,4252,0.010776343,2.052055311,1.140676852,3.826173578,0.037795208,DB0110910000087_,3.275572953,0.718841882,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,heparin,DB01109
,125488,DB09153,10000087,83,7716,45,5654,0.106440119,1.3515103,0.927607263,1.991689908,0.220766868,DB0915310000087_,1.510648029,0.301222708,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,125489,DB09145,10037660,33,966,23,445,0.144462938,0.661139925,0.371749164,1.194073757,0.276291215,DB0914510037660_,1.286299842,-0.413789774,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,water,DB09145
,125495,DB06605,10018627,23,14050,46,12987,0.00234883,0.462181024,0.267251064,0.778853093,0.01108619,DB0660510018627_,4.502055095,-0.771798638,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,apixaban,DB06605
,125497,DB06605,10021789,97,13976,74,12959,0.219665667,1.215416133,0.88800609,1.669393159,0.373051983,DB0660510021789_,0.986037505,0.195086514,NA,10021789,Infection,10021881,Infections and infestations,Infec,apixaban,DB06605
,125498,DB06605,10023232,86,13987,67,12966,0.292782128,1.189876603,0.853686416,1.664473622,0.458382169,DB0660510023232_,0.780052013,0.173849607,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,125500,DB06605,10028391,68,14005,43,12990,0.056542466,1.46675948,0.985930192,2.203355142,0.137026865,DB0660510028391_,1.987578279,0.383055532,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,125505,DB00333,10044565,19,3052,36,3116,0.030066026,0.538900102,0.291312263,0.96720219,0.084844649,DB0033310044565_,2.466933351,-0.618225064,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,methadone,DB00333
,125522,DB00005,10074300,31,128051,27,42392,0.000360304,0.380103242,0.219517699,0.662010271,0.00235002,DB0000510074300_,6.053331292,-0.967312373,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,125525,DB01281,10037087,107,8825,26,1772,0.412661918,0.826375687,0.532371561,1.326202992,0.582098236,DB0128110037087_,0.541116056,-0.190705782,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,abatacept,DB01281
,125528,DB01281,10046735,103,8829,22,1776,0.809461505,0.941767467,0.588049672,1.572340962,0.89735331,DB0128110046735_,0.108305615,-0.059996885,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,abatacept,DB01281
,125547,DB00158,10039101,130,16685,31,8073,0.000256513,2.028988516,1.361245981,3.110100888,0.001774091,DB0015810039101_,6.3344671,0.707537401,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,125548,DB00230,10039101,76,19598,23,8628,0.126096177,1.454751916,0.901534276,2.43268948,0.250250143,DB0023010039101_,1.385294289,0.374835382,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,125551,DB00736,10039101,73,10518,28,5525,0.17245887,1.369480669,0.873589241,2.202445616,0.314077559,DB0073610039101_,1.15811532,0.314431594,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,125561,DB00413,10040753,51,2148,15,1192,0.036700661,1.886462052,1.038721553,3.628649843,0.098968431,DB0041310040753_,2.312954356,0.634703144,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,pramipexole,DB00413
,125563,DB00736,10040753,240,10351,43,5510,4.1209159232903e-13,2.970895726,2.136353291,4.219323391,1.94292870033517e-11,DB0073610040753_,24.66423955,1.088863499,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,125575,DB00051,10013781,79,25652,14,11406,0.000665286,2.509008549,1.409923129,4.79982729,0.0039303,DB0005110013781_,5.539039597,0.919887675,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,125586,DB08895,10028334,376,27738,61,6585,0.004830855,1.463294054,1.112355582,1.953547854,0.019916715,DB0889510028334_,3.916195958,0.380690096,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,125616,DB00264,10064687,35,29572,25,24867,0.604604288,1.177251425,0.684569306,2.052457767,0.747842343,DB0026410064687_,0.290563095,0.16318242,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,125625,DB01050,10016288,53,18055,40,9331,0.079223648,0.684759004,0.4453087,1.060407996,0.177111936,DB0105010016288_,1.730973339,-0.378688321,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,ibuprofen,DB01050
,125653,DB00635,10035759,63,32990,53,23741,0.398618597,0.855429194,0.583949264,1.257350258,0.568438871,DB0063510035759_,0.564861498,-0.156151955,NA,10035759,Pneumothorax,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,125655,DB00904,10035759,38,23031,35,14421,0.117002058,0.679854394,0.417892139,1.108901409,0.236614664,DB0090410035759_,1.44132235,-0.38587663,NA,10035759,Pneumothorax,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,125659,DB00059,10043554,49,778,63,1044,0.84441403,1.04370619,0.695031947,1.559673882,0.921373327,DB0005910043554_,0.081889975,0.042778022,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,pegaspargase,DB00059
,125661,DB01033,10043554,19,1163,38,1266,0.031879488,0.544412554,0.29465262,0.974462402,0.088841426,DB0103310043554_,2.420902225,-0.608047949,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,mercaptopurine,DB01033
,125663,DB00316,10040030,39,65435,20,36933,0.787369052,1.100634935,0.626411143,1.991984135,0.884765643,DB0031610040030_,0.122432479,0.095887227,NA,10040030,Sensory loss,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,125676,DB01109,10043607,69,4343,87,4183,0.10601436,0.763911253,0.547097599,1.063189757,0.22022186,DB0110910043607_,1.513119785,-0.269303658,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,heparin,DB01109
,125680,DB00169,10023874,48,38643,6,18169,0.000627037,3.760969945,1.606963993,10.75578888,0.003737342,DB0016910023874_,5.589380536,1.324676888,female,10023874,Laryngitis,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,125681,DB00316,10023874,60,65414,17,36936,0.012115277,1.992867298,1.147307803,3.643766633,0.041454055,DB0031610023874_,3.183169572,0.689574455,NA,10023874,Laryngitis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,125687,DB00363,10001507,167,4461,360,6528,4.10947555442854e-05,0.678854028,0.559366017,0.821222283,0.000373182,DB0036310001507_,7.893443997,-0.387349155,NA,10001507,Agranulocytosis,10005329,Blood and lymphatic system disorders,Blood,clozapine,DB00363
,125700,DB00722,10042609,78,25325,48,25984,0.00551896,1.667257509,1.148557357,2.442080723,0.02213901,DB0072210042609_,3.810414082,0.511180067,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,lisinopril,DB00722
,125701,DB00761,10042609,50,15257,17,8608,0.074628786,1.65937877,0.940119635,3.071154648,0.169220028,DB0076110042609_,1.776555469,0.506443298,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,potassium chloride,DB00761
,125716,DB00619,10003239,77,2822,53,2441,0.213583191,1.256628423,0.870324034,1.826158149,0.365735125,DB0061910003239_,1.00584591,0.22843228,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,imatinib,DB00619
,125737,DB00514,10053762,56,2110,40,1496,1,0.992607695,0.646041565,1.537401102,1,DB0051410053762_,0,-0.007419763,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,dextromethorphan,DB00514
,125743,DB00863,10006451,138,10535,45,5795,0.001837975,1.686835294,1.194908111,2.421110675,0.009075928,DB0086310006451_,4.702129651,0.522854166,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,ranitidine,DB00863
,125762,DB00760,10013968,23,757,37,978,0.430619679,0.80319613,0.451482323,1.40150003,0.599102221,DB0076010013968_,0.512323042,-0.219156348,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,meropenem,DB00760
,125772,DB00073,10043521,146,7260,33,6374,4.60745198730624e-15,3.88384417,2.642744282,5.861337083,2.83622659218605e-13,DB0007310043521_,28.8911317,1.356825429,female,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rituximab,DB00073
,125777,DB00541,10029350,21,3113,43,4254,0.161493222,0.66740953,0.375405606,1.152291515,0.299470834,DB0054110029350_,1.205738249,-0.404351434,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,vincristine,DB00541
,125778,DB00153,10037153,65,7358,17,3422,0.032107561,1.778132832,1.028152139,3.241083372,0.089339676,DB0015310037153_,2.415309592,0.575563843,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,ergocalciferol,DB00153
,125779,DB00175,10037153,108,8023,45,6061,0.00071234,1.813004876,1.267068582,2.631925578,0.004151633,DB0017510037153_,5.484253531,0.594985621,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,pravastatin,DB00175
,125780,DB00316,10037153,403,65071,142,36811,6.34674266009129e-07,1.605479541,1.322162612,1.958749644,9.56560383145066e-06,DB0031610037153_,11.55733683,0.473422491,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,125785,DB00115,10003553,129,18296,14,10458,6.05224667961342e-13,5.265897727,3.025397776,9.908784069,2.78360986830514e-11,DB0011510003553_,24.30468742,1.66125164,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,125795,DB00115,10037884,93,18332,53,10419,1,0.997294045,0.703613137,1.426329289,1,DB0011510037884_,0,-0.002709623,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,125797,DB00115,10047924,66,18359,27,10445,0.160829387,1.390704407,0.875768145,2.265672823,0.298629795,DB0011510047924_,1.208550616,0.329810387,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,125809,DB00381,10061394,55,29305,15,22872,0.000145509,2.861630782,1.593527863,5.456329653,0.001098419,DB0038110061394_,6.813883742,1.051391666,female,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,125811,DB01076,10061394,54,25693,23,25560,0.000536362,2.335779212,1.408903428,3.988816934,0.003269546,DB0107610061394_,5.723104144,0.848345545,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,125812,DB09140,10008531,77,3664,34,1764,0.758868861,1.090303137,0.716150313,1.691008029,0.865542861,DB0914010008531_,0.144398384,0.086455765,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,125814,DB01225,10013950,36,5008,32,4608,0.903716607,1.035147317,0.623833716,1.724708285,0.957417047,DB0122510013950_,0.043516196,0.034543752,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,125822,DB00641,10018985,10,14114,43,12432,5.08649068990275e-07,0.204873962,0.091749558,0.414221106,7.87387560565924e-06,DB0064110018985_,11.75196016,-1.585360306,male,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,125825,DB00335,10024264,31,8435,30,5435,0.116090447,0.665856484,0.389376298,1.140047875,0.235280977,DB0033510024264_,1.446974831,-0.406681121,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,125826,DB00404,10024264,133,19759,57,9805,0.395197934,1.157851888,0.842019818,1.609832897,0.564978732,DB0040410024264_,0.570967192,0.146566467,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,125828,DB01225,10024264,33,5011,23,4617,0.348430914,1.321929284,0.751846064,2.361600928,0.518015077,DB0122510024264_,0.65775093,0.279092249,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,enoxaparin,DB01225
,125831,DB01109,10030095,34,4378,21,4249,0.106242553,1.571253237,0.88442035,2.853895608,0.220548531,DB0110910030095_,1.511637511,0.451873541,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,125847,DB00395,10016256,116,2068,35,701,0.630456403,1.123413523,0.755650117,1.706691447,0.769328241,DB0039510016256_,0.26223756,0.116371839,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,carisoprodol,DB00395
,125851,DB01015,10013971,40,9847,24,9357,0.079800509,1.5836867,0.930855147,2.748724418,0.178083489,DB0101510013971_,1.7255028,0.459755483,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,125862,DB08932,10013950,100,19343,37,6560,0.623889868,0.916590934,0.622106409,1.37673374,0.763842992,DB0893210013950_,0.269393019,-0.087093998,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,125870,DB00341,10039073,72,11333,8,5060,1.49304212795444e-05,4.018503421,1.931769857,9.670888231,0.000154415,DB0034110039073_,8.775865753,1.39090955,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,125871,DB00425,10039073,72,12623,13,7471,1.35923183511592e-05,3.277807474,1.799486153,6.455932074,0.000142142,DB0042510039073_,8.858683522,1.187174746,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,125872,DB00471,10039073,104,14085,12,5453,5.8903634119542e-06,3.355384652,1.839316745,6.707957981,6.81635677899721e-05,DB0047110039073_,9.593600332,1.210566414,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,125874,DB00476,10039073,148,17109,27,6150,0.000729459,1.970390493,1.299365674,3.093313889,0.004235437,DB0047610039073_,5.464268792,0.678231743,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,125875,DB05676,10039073,117,47012,25,25304,5.77517591949954e-06,2.518959199,1.624345352,4.051306379,6.70496903904794e-05,DB0567610039073_,9.610076566,0.9238458,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,125877,DB00060,10062355,44,9464,9,2456,0.611425583,1.26868701,0.610166754,2.959777289,0.753478583,DB0006010062355_,0.283054684,0.237982515,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,125888,DB00046,10047531,43,5416,25,4667,0.142623341,1.482074478,0.883462949,2.536366159,0.273489295,DB0004610047531_,1.296492799,0.39344278,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,insulin lispro,DB00046
,125896,DB00381,10057362,60,29300,47,22840,1,0.995134468,0.667735589,1.490828182,1,DB0038110057362_,0,-0.004877407,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,125914,DB00316,10010947,47,65427,18,36935,0.195980332,1.474024853,0.839954767,2.697131155,0.344237564,DB0031610010947_,1.066423266,0.387996655,NA,10010947,Coordination abnormal,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,125927,DB00695,10013887,64,27985,37,20491,0.268566784,1.266525034,0.831740657,1.954024468,0.43099566,DB0069510013887_,0.841657258,0.236276956,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,125928,DB01156,10013887,38,13584,20,6308,0.672395496,0.882315103,0.500221727,1.601746795,0.801083994,DB0115610013887_,0.221789476,-0.125206027,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,125939,DB00437,10049848,34,6887,61,11485,0.831821614,0.929497335,0.591721985,1.438318166,0.912158161,DB0043710049848_,0.091941882,-0.073111339,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,125950,DB00153,10005750,88,7335,38,3401,0.772979602,1.073747858,0.724361322,1.618744927,0.875860279,DB0015310005750_,0.132548699,0.071155199,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,ergocalciferol,DB00153
,125962,DB05676,10036018,54,47075,44,25285,0.043808293,0.659173026,0.434366283,1.005207023,0.11320213,DB0567610036018_,2.178580295,-0.41676922,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,apremilast,DB05676
,125963,DB00230,10014062,67,19607,12,8639,0.002119618,2.459995692,1.318769467,4.999545502,0.010202938,DB0023010014062_,4.585079548,0.900159599,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,125964,DB00316,10014062,83,65391,40,36913,0.452833825,1.171307199,0.793798935,1.754009783,0.620467437,DB0031610014062_,0.477282154,0.15812039,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,125971,DB01162,10013709,10,263,80,1622,0.532993129,0.771006633,0.351571684,1.517764703,0.689743465,DB0116210013709_,0.37143554,-0.260058302,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,terazosin,DB01162
,125983,DB00820,10024670,56,11859,17,5799,0.103536794,1.610769693,0.92137067,2.959863315,0.21634124,DB0082010024670_,1.530898303,0.476712135,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,tadalafil,DB00820
,125985,DB06643,10030973,46,52375,7,7508,0.835578509,0.942005684,0.422224339,2.47395622,0.914871949,DB0664310030973_,0.08897117,-0.059743971,NA,10030973,Oral discomfort,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,125987,DB00169,10001488,32,38659,49,18126,1.37984119271978e-07,0.306207112,0.189707484,0.488032122,2.43580428143984e-06,DB0016910001488_,12.92523356,-1.183493568,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,125993,DB00331,10001497,62,24884,107,20645,3.96961865748572e-06,0.480734971,0.34558418,0.663772086,4.82838622915373e-05,DB0033110001497_,9.938413167,-0.732439156,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,metformin,DB00331
,126004,DB00169,10013395,53,38638,25,18150,1,0.995859054,0.607818676,1.672964851,1,DB0016910013395_,0,-0.004149544,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,126006,DB00169,10014387,30,38661,25,18150,0.041730508,0.563391949,0.320150225,0.999343275,0.109191463,DB0016910014387_,2.214652392,-0.573779714,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,cholecalciferol,DB00169
,126008,DB00927,10014387,27,7470,30,4986,0.058142374,0.600766145,0.343173986,1.047000782,0.139942482,DB0092710014387_,1.966523781,-0.50954953,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,famotidine,DB00927
,126018,DB00927,10021015,49,7448,23,4993,0.184621008,1.428163992,0.852402086,2.459396704,0.329720848,DB0092710021015_,1.109508898,0.356389698,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,famotidine,DB00927
,126034,DB00169,10039020,24,38667,30,18145,0.00036996,0.37541671,0.209973755,0.664460862,0.002402571,DB0016910039020_,6.031215713,-0.979718643,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,126035,DB00331,10039020,57,24889,75,20677,0.010851919,0.631398526,0.439175628,0.903473763,0.038012087,DB0033110039020_,3.269851103,-0.459818038,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,126036,DB00381,10039020,50,29310,98,22789,4.45249591973377e-08,0.396697268,0.276230431,0.563510902,8.69295880518818e-07,DB0038110039020_,13.95558229,-0.924581838,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,126037,DB00722,10039020,46,25357,75,25957,0.013739998,0.627855008,0.425040859,0.918701647,0.045852326,DB0072210039020_,3.082329346,-0.465446018,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,126041,DB00722,10040752,20,25383,45,25987,0.002734477,0.455054759,0.254446791,0.786813439,0.012531729,DB0072210040752_,4.37949157,-0.787337519,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,lisinopril,DB00722
,126053,DB00381,10053459,33,29327,18,22869,0.259168435,1.429609602,0.781688661,2.697399021,0.420286427,DB0038110053459_,0.866818832,0.357401401,NA,10053459,Secretion discharge,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,126074,DB00423,10016322,53,2414,22,1018,1,1.015932287,0.60363225,1.763942197,1,DB0042310016322_,0,0.0158067,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,methocarbamol,DB00423
,126075,DB00476,10016322,443,16814,137,6040,0.138987839,1.161568062,0.954643719,1.4206368,0.268407564,DB0047610016322_,1.315248693,0.14977087,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,126076,DB01175,10022116,69,10655,9,4883,6.78643414428309e-05,3.513019533,1.745554896,8.012951199,0.000571735,DB0117510022116_,7.466834392,1.256475934,female,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,126081,DB00715,10047513,39,4804,19,2268,0.888556669,0.969093873,0.545262316,1.779647814,0.953826126,DB0071510047513_,0.047273882,-0.031393796,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,paroxetine,DB00715
,126091,DB00620,10010774,83,4745,49,3083,0.653569071,1.100580513,0.761628783,1.605167765,0.787705215,DB0062010010774_,0.238631352,0.09583778,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,triamcinolone,DB00620
,126092,DB00335,10013786,56,8410,15,5450,0.001421929,2.419197015,1.347847537,4.610291401,0.007354465,DB0033510013786_,4.912447637,0.883435673,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,atenolol,DB00335
,126093,DB00620,10013786,38,4790,25,3107,1,0.985935188,0.578537648,1.707733917,1,DB0062010013786_,0,-0.014164659,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,triamcinolone,DB00620
,126097,DB00620,10027175,45,4783,20,3112,0.163130631,1.463867274,0.844969172,2.622363655,0.301562765,DB0062010027175_,1.19877711,0.381081751,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,triamcinolone,DB00620
,126098,DB00169,10033553,46,38645,30,18145,0.17566515,0.719932443,0.444661272,1.181669781,0.318164236,DB0016910033553_,1.145187564,-0.3285979,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,126105,DB00331,10040844,73,24873,47,20705,0.198541178,1.292912503,0.883632654,1.908022601,0.347309589,DB0033110040844_,1.057538708,0.256897428,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,126106,DB00169,10062519,76,38615,26,18149,0.168665141,1.373872067,0.869556369,2.235764378,0.309091401,DB0016910062519_,1.174118251,0.31763308,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,126108,DB00381,10062519,39,29321,33,22854,0.72340799,0.921159886,0.564325868,1.511893929,0.837386203,DB0038110062519_,0.177469901,-0.082121658,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,126111,DB00335,10068319,55,8411,25,5440,0.16801927,1.422863623,0.870605247,2.38588701,0.308180909,DB0033510068319_,1.177068303,0.352671477,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atenolol,DB00335
,126112,DB00620,10068319,38,4790,14,3118,0.0863988,1.766715604,0.933869896,3.536271414,0.189036706,DB0062010068319_,1.66581407,0.569122232,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,triamcinolone,DB00620
,126115,DB06403,10005750,64,21407,25,6636,0.319377321,0.793586682,0.492332427,1.316397587,0.487575208,DB0640310005750_,0.718310727,-0.231192505,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,ambrisentan,DB06403
,126116,DB06403,10037087,267,21204,65,6596,0.079605893,1.277774253,0.969592483,1.705086077,0.177755715,DB0640310037087_,1.727345061,0.2451197,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ambrisentan,DB06403
,126152,DB00285,10035528,40,10911,30,3688,0.001362644,0.450698439,0.273328785,0.750503863,0.007106835,DB0028510035528_,4.946698283,-0.796956814,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,venlafaxine,DB00285
,126153,DB00557,10035528,50,5937,30,3037,0.479258644,0.852587451,0.530424755,1.391854983,0.644364554,DB0055710035528_,0.439490635,-0.159479493,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,hydroxyzine,DB00557
,126155,DB01104,10035528,106,15357,48,7238,0.86270251,1.040808625,0.732503184,1.497755404,0.936336136,DB0110410035528_,0.065780747,0.039997935,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,sertraline,DB01104
,126158,DB00972,10046571,55,2449,11,1168,0.007226385,2.384179503,1.228476148,5.071925247,0.027454363,DB0097210046571_,3.595230185,0.868855041,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,azelastine,DB00972
,126160,DB00175,10047942,89,8042,70,6036,0.809123362,0.95425733,0.68857823,1.326919024,0.897075589,DB0017510047942_,0.108615152,-0.046821906,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,pravastatin,DB00175
,126161,DB00285,10047942,91,10860,20,3698,0.079774028,1.549251838,0.945398725,2.659035624,0.178054628,DB0028510047942_,1.725664879,0.437772129,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,venlafaxine,DB00285
,126163,DB01104,10047942,137,15326,65,7221,1,0.993060817,0.732929249,1.357364467,1,DB0110410047942_,0,-0.006963371,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,sertraline,DB01104
,126165,DB00557,10061818,43,5944,13,3054,0.118214608,1.699386657,0.895306185,3.450025138,0.238552914,DB0055710061818_,1.433164133,0.530267396,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,126185,DB01592,10005557,34,6242,21,3046,0.390904949,0.79011394,0.444696724,1.43518685,0.560751853,DB0159210005557_,0.5784768,-0.235578117,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,iron,DB01592
,126190,DB01076,10005746,34,25713,32,25551,0.902128554,1.055825694,0.63192912,1.767885641,0.957195726,DB0107610005746_,0.043747388,0.054323109,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,atorvastatin,DB01076
,126233,DB09153,10007559,44,7755,33,5666,0.908438071,0.974158948,0.605420087,1.581392068,0.959026229,DB0915310007559_,0.041836854,-0.026180798,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,sodium chloride,DB09153
,126241,DB00863,10038687,34,10639,28,5812,0.111389813,0.663344028,0.389996407,1.13689501,0.228136322,DB0086310038687_,1.477811926,-0.410461527,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,126246,DB01222,10038687,45,9229,40,5365,0.05514721,0.654032328,0.417023618,1.028961995,0.13459094,DB0122210038687_,2.005515178,-0.424598497,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,126259,DB00316,10034972,52,65422,21,36932,0.223116105,1.39785349,0.827372879,2.443556695,0.377363544,DB0031610034972_,0.974546249,0.334937839,NA,10034972,Photosensitivity reaction,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,126267,DB00996,10040844,95,38858,69,22356,0.144345655,0.792131803,0.57458162,1.096739293,0.276086996,DB0099610040844_,1.28703926,-0.233027483,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,126268,DB01050,10040844,54,18054,32,9339,0.569399567,0.872923009,0.55316541,1.398061933,0.720261201,DB0105010040844_,0.328141353,-0.135907918,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,126273,DB00316,10049414,103,65371,75,36878,0.100776537,0.774763151,0.569657791,1.057898921,0.212031639,DB0031610049414_,1.551019775,-0.255197908,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,126274,DB00421,10049414,54,8849,30,5222,0.821846915,1.062223096,0.666716856,1.721801023,0.905147329,DB0042110049414_,0.099657554,0.060363972,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,126282,DB00928,10012735,22,813,35,1251,1,0.967223966,0.536375952,1.709540876,1,DB0092810012735_,0,-0.033325201,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,azacitidine,DB00928
,126286,DB00016,10017413,45,2717,29,2261,0.292839192,1.29122897,0.789162298,2.143201145,0.458421343,DB0001610017413_,0.779966554,0.255594455,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,erythropoietin,DB00016
,126288,DB00404,10017413,73,19819,30,9832,0.403997653,1.207120988,0.778560587,1.914629039,0.573678631,DB0040410017413_,0.555685916,0.188238175,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,alprazolam,DB00404
,126302,DB00016,10029354,32,2730,33,2257,0.382965033,0.801726142,0.475655245,1.349833774,0.553029111,DB0001610029354_,0.592344636,-0.220988199,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,erythropoietin,DB00016
,126303,DB00115,10029354,162,18263,113,10359,0.101121038,0.813189261,0.634774345,1.044675673,0.212501318,DB0011510029354_,1.548807089,-0.206791403,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,cyanocobalamin,DB00115
,126304,DB00404,10029354,102,19790,45,9817,0.539848867,1.124389181,0.783657947,1.635836785,0.695552748,DB0040410029354_,0.363048429,0.117239938,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,alprazolam,DB00404
,126311,DB00715,10035528,41,4802,17,2270,0.777743348,1.140061062,0.631949925,2.145234325,0.878833433,DB0071510035528_,0.129159895,0.131081825,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,paroxetine,DB00715
,126312,DB00928,10035528,20,815,48,1238,0.100890116,0.633054031,0.35313412,1.096469289,0.212128531,DB0092810035528_,1.550562912,-0.457199504,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,azacitidine,DB00928
,126318,DB06637,10003988,115,6047,39,1980,0.850492986,0.965515862,0.663541202,1.431628242,0.926141691,DB0663710003988_,0.076728042,-0.035092748,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,dalfampridine,DB06637
,126325,DB00108,10013745,55,10139,14,3281,0.484209055,1.271262835,0.696320227,2.478880095,0.648383046,DB0010810013745_,0.433273637,0.240010764,NA,10013745,Drug specific antibody present,10022891,Investigations,Inv,natalizumab,DB00108
,126335,DB01202,10013752,35,6679,42,5676,0.137160926,0.70821574,0.438311483,1.137949943,0.265767937,DB0120210013752_,1.32513177,-0.345006514,NA,10013752,Drug withdrawal convulsions,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,126341,DB00484,10011224,45,2462,23,1757,0.21579717,1.396160431,0.823562368,2.427145966,0.368350452,DB0048410011224_,0.998720478,0.33372592,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,brimonidine,DB00484
,126350,DB09140,10017577,83,3658,20,1778,0.003939396,2.016918309,1.221532535,3.482340686,0.01686465,DB0914010017577_,4.082535582,0.701570757,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,126358,DB01409,10049848,36,5995,20,3946,0.586080215,1.18473439,0.666613569,2.163414184,0.733315171,DB0140910049848_,0.310179695,0.169518606,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,tiotropium,DB01409
,126366,DB01409,10022000,92,5939,32,3934,0.001579323,1.904284603,1.258265061,2.949553903,0.008014773,DB0140910022000_,4.826468801,0.644106402,NA,10022000,Influenza,10021881,Infections and infestations,Infec,tiotropium,DB01409
,126367,DB00007,10016173,9,1938,144,4308,4.5603261488121e-14,0.138952638,0.062167733,0.27200586,2.42893967216872e-12,DB0000710016173_,26.7435663,-1.973622135,male,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,leuprolide,DB00007
,126371,DB00758,10042361,24,8276,90,9984,1.16870105307413e-07,0.321731103,0.195865638,0.509909279,2.09259585695187e-06,DB0075810042361_,13.07710523,-1.134039165,male,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,126381,DB00331,10043458,30,24916,36,20716,0.139623218,0.692873967,0.41200643,1.157463996,0.269301154,DB0033110043458_,1.311924994,-0.366907163,NA,10043458,Thirst,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,126391,DB00285,10014387,66,10885,26,3692,0.547660736,0.861032131,0.538423382,1.414848332,0.70229357,DB0028510014387_,0.353403772,-0.149623457,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,venlafaxine,DB00285
,126403,DB14513,10035226,50,7127,66,3498,1.50004528399659e-07,0.371862067,0.251640985,0.546539478,2.62420567652914e-06,DB1451310035226_,12.85073231,-0.989232281,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,magnesium,DB14513
,126414,DB00213,10062060,31,18864,21,13400,0.889203056,1.048613483,0.583315185,1.920910614,0.953968782,DB0021310062060_,0.047124331,0.047468799,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,126420,DB09053,10042128,26,2259,56,3996,0.487496524,0.821340228,0.493547328,1.33422307,0.651308637,DB0905310042128_,0.428771652,-0.196817849,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,ibrutinib,DB09053
,126423,DB00758,10035528,63,8237,86,9988,0.508957048,0.888306664,0.630509439,1.245613678,0.669437756,DB0075810035528_,0.401317089,-0.118438253,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,clopidogrel,DB00758
,126429,DB06273,10019211,172,4923,31,1379,0.024245836,1.55405253,1.049915155,2.369132081,0.071816745,DB0627310019211_,2.633637619,0.440866055,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,tocilizumab,DB06273
,126439,DB06605,10010305,88,13985,95,12938,0.299911353,0.856972313,0.633209477,1.158749986,0.465949696,DB0660510010305_,0.7636776,-0.154349668,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,apixaban,DB06605
,126467,DB01222,10022004,66,9208,26,5379,0.1034043,1.482844885,0.927611935,2.436095901,0.216124526,DB0122210022004_,1.531900529,0.393962462,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,126469,DB06605,10022004,45,14028,25,13008,0.041643874,1.669080928,1.00120789,2.841981811,0.10900311,DB0660510022004_,2.216378868,0.512273132,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,126473,DB00215,10030095,58,11045,13,5263,0.010747983,2.125862326,1.15001298,4.233177323,0.037713353,DB0021510030095_,3.277741053,0.754177521,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,126476,DB01224,10012239,59,8049,93,5824,2.90364989830363e-06,0.459059085,0.324958512,0.644163264,3.68351532707098e-05,DB0122410012239_,10.20905792,-0.778576352,NA,10012239,Delusion,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,126484,DB00852,10028813,81,1085,11,460,0.000122803,3.12023526,1.634965907,6.558854294,0.000950776,DB0085210028813_,6.958231568,1.137908403,female,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pseudoephedrine,DB00852
,126496,DB01050,10016334,60,18048,18,9353,0.041865968,1.727398944,1.005374294,3.110939059,0.109453648,DB0105010016334_,2.212254121,0.546616777,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,126520,DB00451,10040752,41,47230,11,15408,0.63210869,1.215951743,0.613601507,2.623797326,0.770799885,DB0045110040752_,0.260326492,0.195527097,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,126536,DB00184,10057852,39,1255,36,946,0.408042467,0.816678171,0.501466465,1.333292353,0.577463009,DB0018410057852_,0.549110892,-0.202510177,NA,10057852,Nicotine dependence,10037175,Psychiatric disorders,Psych,nicotine,DB00184
,126539,DB08935,10016288,17,515,42,771,0.101839163,0.606177546,0.319836187,1.101939769,0.213685831,DB0893510016288_,1.543248422,-0.500582355,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,obinutuzumab,DB08935
,126543,DB00110,10011906,31,500,40,648,1,1.004396666,0.59826892,1.672734485,1,DB0011010011906_,0,0.004387029,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,palivizumab,DB00110
,126544,DB00869,10011906,45,1260,47,882,0.066197421,0.670350386,0.431153238,1.041103293,0.154508655,DB0086910011906_,1.867505162,-0.39995474,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dorzolamide,DB00869
,126551,DB00722,10048010,63,25340,44,25988,0.05294356,1.468413903,0.983019346,2.210692433,0.130552227,DB0072210048010_,2.035981923,0.384182841,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,126553,DB00829,10048010,44,8008,25,4429,0.900354791,0.973390239,0.581890694,1.66207786,0.956698706,DB0082910048010_,0.044266769,-0.026970209,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,126559,DB00203,10037884,56,13822,24,8914,0.107861162,1.504772625,0.916737536,2.540669331,0.222861348,DB0020310037884_,1.50120546,0.408641807,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,sildenafil,DB00203
,126560,DB00374,10037884,53,17663,13,5711,0.472787117,1.318169235,0.708244261,2.63793543,0.638783282,DB0037410037884_,0.448190034,0.276243831,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,treprostinil,DB00374
,126565,DB00169,10011781,188,38503,34,18141,1.90966667546542e-08,2.605188353,1.799871269,3.874938576,4.01404146858126e-07,DB0016910011781_,14.72829707,0.957504977,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,126566,DB14513,10011781,43,7134,8,3556,0.006880649,2.679009267,1.243334355,6.603472972,0.02644314,DB1451310011781_,3.632758498,0.98544705,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,magnesium,DB14513
,126574,DB06643,10022004,232,52189,23,7492,0.106230608,1.448025951,0.941036101,2.331474591,0.220548007,DB0664310022004_,1.511639888,0.370201216,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,126575,DB14513,10022004,58,7119,13,3551,0.007485916,2.225300654,1.203114698,4.43318972,0.028252899,DB1451310022004_,3.566559215,0.799892032,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,126577,DB01373,10048334,134,22586,8,7373,3.39648969214985e-09,5.467770006,2.694551064,12.93056911,8.4711383205684e-08,DB0137310048334_,16.28401585,1.698870856,female,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,126593,DB01224,10033425,103,8005,38,5879,0.000207031,1.99054857,1.357628013,2.97346645,0.001482781,DB0122410033425_,6.513835801,0.688410264,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,quetiapine,DB01224
,126594,DB00169,10003591,46,38645,20,18155,0.8950207,1.080512041,0.62630974,1.928960906,0.955976233,DB0016910003591_,0.045022227,0.077435041,NA,10003591,Ataxia,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,126597,DB00316,10003591,53,65421,24,36929,0.407436952,1.246602244,0.756021839,2.111782059,0.576908316,DB0031610003591_,0.550071923,0.220421645,NA,10003591,Ataxia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,126600,DB00555,10003591,62,6985,48,3438,0.024511095,0.635769981,0.428138018,0.949182971,0.072418832,DB0055510003591_,2.625288898,-0.452918446,NA,10003591,Ataxia,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,126627,DB00231,10016173,135,3161,58,2081,0.006871725,1.532217814,1.112339008,2.132794406,0.026416569,DB0023110016173_,3.633763835,0.426716237,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,temazepam,DB00231
,126630,DB00316,10017076,60,65414,16,36937,0.005780083,2.117477455,1.203875009,3.939188422,0.022981316,DB0031610017076_,3.773073743,0.750225501,NA,10017076,Fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,126642,DB00423,10017577,43,2424,8,1032,0.029797654,2.287921812,1.058468224,5.654638156,0.084259193,DB0042310017577_,2.473857604,0.8276439,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,methocarbamol,DB00423
,126643,DB00843,10017577,50,2144,55,2118,0.621966542,0.898088979,0.596874502,1.348542235,0.76216273,DB0084310017577_,0.27159519,-0.10748613,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,donepezil,DB00843
,126644,DB00321,10024264,39,7408,16,2834,0.879906091,0.932489836,0.508267743,1.790373362,0.94955584,DB0032110024264_,0.05176094,-0.069897027,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,126646,DB00736,10024264,35,10556,20,5533,0.776932315,0.917281396,0.514499225,1.678572536,0.878478692,DB0073610024264_,0.129563626,-0.086340988,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,126647,DB00321,10027175,99,7348,19,2831,0.003668958,2.007370704,1.217352994,3.481062042,0.015918142,DB0032110027175_,4.140295791,0.696825758,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,126648,DB00564,10027175,53,2551,26,1437,0.636427388,1.148268802,0.701839983,1.921831876,0.773999962,DB0056410027175_,0.256183454,0.138255419,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,carbamazepine,DB00564
,126649,DB00321,10028372,68,7379,25,2825,0.907896553,1.041299181,0.648237858,1.72303357,0.958771936,DB0032110028372_,0.042102046,0.040469146,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,amitriptyline,DB00321
,126651,DB00564,10028372,38,2566,12,1451,0.101734362,1.79042635,0.912366804,3.77557344,0.213525588,DB0056410028372_,1.543998604,0.582453776,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,carbamazepine,DB00564
,126652,DB00787,10028372,99,16901,109,17139,0.578278649,0.921071761,0.693831318,1.221441424,0.727049209,DB0078710028372_,0.318761116,-0.082217329,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,126658,DB00722,10039203,53,25350,56,25976,0.923706377,0.9697943,0.653096074,1.438460426,0.966829343,DB0072210039203_,0.03373328,-0.030671292,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,126675,DB00996,10039227,46,38907,21,22404,0.446635824,1.261376132,0.737413595,2.225920607,0.614378321,DB0099610039227_,0.487144382,0.232203294,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,126686,DB00787,10042209,41,16959,12,17236,4.64137390890575e-05,3.472727145,1.789651058,7.260515143,0.000414468,DB0078710042209_,7.788515957,1.244940206,female,10042209,Stress,10037175,Psychiatric disorders,Psych,acyclovir,DB00787
,126692,DB08868,10042209,113,9089,16,2495,0.009587951,1.938564847,1.140769762,3.513749117,0.03443357,DB0886810042209_,3.368723316,0.661947929,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,fingolimod,DB08868
,126693,DB00169,10057668,143,38548,65,18110,0.881653741,1.033538714,0.765287268,1.40875111,0.950483399,DB0016910057668_,0.050784582,0.032988558,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,126694,DB00186,10057668,74,16827,38,9970,0.494673261,1.153838184,0.76949814,1.755474659,0.657155228,DB0018610057668_,0.419835021,0.143093936,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,126696,DB00321,10057668,37,7410,24,2826,0.045020541,0.58798913,0.341808509,1.029361739,0.115603039,DB0032110057668_,2.157593037,-0.531046817,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,126698,DB00555,10057668,44,7003,40,3446,0.006996741,0.541291594,0.343964396,0.854173606,0.026781613,DB0055510057668_,3.620039719,-0.613797155,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,126700,DB00722,10057668,53,25350,49,25983,0.621331248,1.108638814,0.737151594,1.670211713,0.761615028,DB0072210057668_,0.272314064,0.103132969,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,126702,DB00787,10057668,57,16943,47,17201,0.326206093,1.231223525,0.821612025,1.852977787,0.494738742,DB0078710057668_,0.703725449,0.208008411,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,126703,DB00843,10057668,33,2161,21,2152,0.131511265,1.564716907,0.875505764,2.855720123,0.257900817,DB0084310057668_,1.355180199,0.447704917,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,donepezil,DB00843
,126708,DB08868,10057668,126,9076,41,2470,0.34193049,0.836353296,0.581892387,1.224245944,0.511155259,DB0886810057668_,0.671081901,-0.178704153,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,126718,DB00982,10047700,40,3324,21,2080,0.597103907,1.191833244,0.683998886,2.134113351,0.742395301,DB0098210047700_,0.297873427,0.175492663,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,isotretinoin,DB00982
,126720,DB01050,10039580,47,18061,6,9365,0.000222893,4.061310825,1.732145734,11.62966161,0.001578112,DB0105010039580_,6.45152626,1.401505785,female,10039580,Scar,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,126727,DB11089,10049438,34,10141,27,8380,0.898297495,1.040591839,0.608868637,1.794805918,0.956365087,DB1108910049438_,0.044615548,0.039789628,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,126735,DB00996,10028347,69,38884,27,22398,0.090403888,1.47204453,0.930611733,2.390582774,0.195883785,DB0099610028347_,1.63023373,0.386652271,NA,10028347,Muscle twitching,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,126743,DB01137,10028411,111,7661,52,5541,0.010398567,1.543861339,1.098823592,2.193665684,0.036722602,DB0113710028411_,3.304362865,0.434286641,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,126744,DB09270,10028411,72,3042,42,2326,0.181426712,1.310727203,0.880045653,1.97397973,0.325648806,DB0927010028411_,1.12193576,0.2705821,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ubidecarenone,DB09270
,126751,DB00005,10001497,38,128044,18,42401,0.216766761,0.699083585,0.389253986,1.301376676,0.369585464,DB0000510001497_,0.99537327,-0.357984966,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,126763,DB00722,10016326,41,25362,15,26017,0.000408755,2.803969056,1.51898564,5.453834048,0.002609696,DB0072210016326_,5.948521597,1.031035934,female,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,126766,DB01362,10028813,41,825,28,562,1,0.997490782,0.594204693,1.696206328,1,DB0136210028813_,0,-0.002512371,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,iohexol,DB01362
,126772,DB00999,10005555,44,21386,20,12219,0.437058286,1.257005135,0.725031623,2.252378314,0.605607793,DB0099910005555_,0.501522708,0.228732014,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,126775,DB00829,10005557,34,8018,19,4435,1,0.9898104,0.548063625,1.839280021,1,DB0082910005557_,0,-0.010241869,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,diazepam,DB00829
,126781,DB01076,10012267,44,25703,41,25542,0.828356437,1.066476087,0.680664536,1.674169649,0.909762627,DB0107610012267_,0.094571563,0.064359836,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,126819,DB00989,10012735,41,793,33,845,0.284599301,1.323671791,0.807535486,2.184365609,0.449169452,DB0098910012735_,0.800355064,0.280409535,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,rivastigmine,DB00989
,126820,DB01065,10012735,282,4049,141,2910,0.000537994,1.437321578,1.163254236,1.782238381,0.00327822,DB0106510012735_,5.720454817,0.362781367,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,melatonin,DB01065
,126824,DB00989,10019063,61,773,129,749,1.0591952114191e-06,0.458386997,0.326766506,0.637478346,1.50572991520557e-05,DB0098910019063_,11.10364769,-0.78004148,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,rivastigmine,DB00989
,126826,DB01065,10019063,56,4275,83,2968,1.16278774576903e-05,0.468466018,0.326546009,0.667762706,0.000123891,DB0106510019063_,8.996109517,-0.758291713,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,melatonin,DB01065
,126827,DB01136,10019063,45,9839,43,11072,0.455626612,1.177646709,0.757191695,1.833770437,0.623016038,DB0113610019063_,0.473183017,0.163518133,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,carvedilol,DB01136
,126833,DB01065,10020772,64,4267,39,3012,0.545661026,1.158318941,0.763725578,1.776934671,0.70039555,DB0106510020772_,0.356110033,0.146969765,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,melatonin,DB01065
,126839,DB00338,10029412,50,33624,31,22241,0.821017365,1.066882401,0.668072253,1.72835927,0.904700649,DB0033810029412_,0.100151165,0.064740752,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,126841,DB00722,10029412,43,25360,36,25996,0.430758341,1.224392607,0.7677568,1.962964641,0.599215844,DB0072210029412_,0.512133405,0.20244489,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,126855,DB01136,10047571,48,9836,39,11076,0.133183519,1.385898388,0.8885353,2.173732911,0.260190182,DB0113610047571_,1.346342446,0.326348585,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,carvedilol,DB01136
,126874,DB01267,10057362,44,2808,63,3652,0.694321246,0.908321423,0.601596966,1.36099325,0.815971973,DB0126710057362_,0.203375271,-0.096156972,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,paliperidone,DB01267
,126875,DB01267,10073317,26,2826,39,3676,0.616501456,0.867217994,0.505569582,1.46506938,0.757634803,DB0126710073317_,0.277553799,-0.142464899,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,paliperidone,DB01267
,126881,DB01611,10020642,68,11845,6,2355,0.058042232,2.253188387,0.981766212,6.36207293,0.139768226,DB0161110020642_,1.967769755,0.812346274,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxychloroquine,DB01611
,126883,DB01611,10022437,130,11783,30,2331,0.453598178,0.85728587,0.571128713,1.324657281,0.621142386,DB0161110022437_,0.476194938,-0.153983846,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,hydroxychloroquine,DB01611
,126884,DB01611,10028334,105,11808,15,2346,0.267283824,1.39072029,0.804064993,2.577778871,0.42957934,DB0161110028334_,0.844948828,0.329821807,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,126893,DB00158,10043554,93,16722,66,8038,0.017300305,0.677324568,0.488213787,0.944268967,0.055156593,DB0015810043554_,2.897579002,-0.3896047,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,folic acid,DB00158
,126895,DB06724,10043554,63,7866,59,3860,0.000459852,0.523999038,0.360717917,0.762189508,0.002879963,DB0672410043554_,5.849977739,-0.64626543,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,calcium carbonate,DB06724
,126896,DB01118,10048959,47,3016,58,4651,0.269595368,1.249589722,0.829659779,1.873569238,0.43215821,DB0111810048959_,0.838963531,0.222815275,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,126897,DB00982,10028411,63,3301,47,2054,0.373315561,0.834095443,0.560191046,1.249399073,0.543055967,DB0098210028411_,0.610542895,-0.181407444,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,isotretinoin,DB00982
,126917,DB09153,10070863,38,7761,21,5678,0.355577098,1.323832039,0.756505796,2.377208139,0.525311602,DB0915310070863_,0.643763664,0.28053059,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium chloride,DB09153
,126936,DB00441,10037377,40,2234,34,1860,1,0.979514413,0.601781854,1.602462451,1,DB0044110037377_,0,-0.020698327,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gemcitabine,DB00441
,126943,DB00404,10021114,51,19841,11,9851,0.009768539,2.301885893,1.184079268,4.900785403,0.034934155,DB0040410021114_,3.354290277,0.833728741,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,alprazolam,DB00404
,126955,DB00563,10003983,61,46585,8,15340,0.011207754,2.510933787,1.196727346,6.077637578,0.03899607,DB0056310003983_,3.24429442,0.920654711,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,126956,DB00563,10011968,43,46603,10,15338,0.425384907,1.41518622,0.700051928,3.159345365,0.594146463,DB0056310011968_,0.520629419,0.347261127,NA,10011968,Decreased immune responsiveness,10021428,Immune system disorders,Immun,methotrexate,DB00563
,126957,DB00563,10025082,193,46453,60,15288,0.770337246,1.058607205,0.788065483,1.439960164,0.874204063,DB0056310025082_,0.134441449,0.056954086,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,126958,DB00563,10042609,236,46410,60,15288,0.079049721,1.295669125,0.971591471,1.751245812,0.176775729,DB0056310042609_,1.732873417,0.25902726,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,methotrexate,DB00563
,126961,DB00563,10072005,41,46605,9,15339,0.326455401,1.499315481,0.717603711,3.50901284,0.494974631,DB0056310072005_,0.703248768,0.405008658,NA,10072005,Spinal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,126963,DB00682,10027091,40,19419,11,16353,0.000586425,3.062019262,1.541427725,6.618302046,0.003527677,DB0068210027091_,5.647115768,1.119074588,female,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,126970,DB00373,10016173,43,1789,25,1262,0.53376818,1.213247533,0.720208335,2.084392978,0.690403763,DB0037310016173_,0.370478688,0.193300676,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,timolol,DB00373
,126973,DB11065,10016173,53,3133,26,2662,0.022749303,1.731848731,1.060534881,2.893763991,0.068297107,DB1106510016173_,2.683887873,0.549189469,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,pancrelipase amylase,DB11065
,126992,DB00722,10033664,38,25365,23,26009,0.053862214,1.694092753,0.983403113,2.979571117,0.132252993,DB0072210033664_,2.023038576,0.527147348,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,127002,DB09053,10000081,33,2252,48,4004,0.415119675,1.222301546,0.757694609,1.950414144,0.584365341,DB0905310000081_,0.537228908,0.200735595,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ibrutinib,DB09053
,127003,DB09053,10003549,66,2219,126,3926,0.647680188,0.926761456,0.674198533,1.264220546,0.78282977,DB0905310003549_,0.244840014,-0.076059076,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ibrutinib,DB09053
,127004,DB00285,10028411,101,10850,19,3699,0.015128675,1.812299002,1.100775032,3.138889605,0.049651295,DB0028510028411_,3.002730807,0.594596206,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,venlafaxine,DB00285
,127005,DB00571,10028411,45,5078,18,2591,0.424350484,1.275607842,0.722082161,2.34634373,0.593174455,DB0057110028411_,0.522266732,0.243422804,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,propranolol,DB00571
,127006,DB00813,10028411,54,10518,22,10146,0.000488062,2.367475061,1.416779926,4.085915876,0.003032727,DB0081310028411_,5.798293052,0.861824012,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fentanyl,DB00813
,127007,DB00285,10043882,51,10900,17,3701,1,1.018628223,0.577686017,1.883971945,1,DB0028510043882_,0,0.018456843,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,venlafaxine,DB00285
,127014,DB00285,10047571,70,10881,13,3705,0.042754296,1.833504946,1.004212951,3.617516768,0.111233956,DB0028510047571_,2.19611958,0.606229406,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,venlafaxine,DB00285
,127037,DB00904,10020993,48,23021,60,14396,0.00034029,0.50027309,0.334810076,0.744052672,0.002240614,DB0090410020993_,6.101005467,-0.69260115,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,127040,DB00470,10003549,37,882,34,919,0.629840284,1.13380992,0.685479148,1.880493788,0.768889853,DB0047010003549_,0.262807554,0.125583572,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,dronabinol,DB00470
,127063,DB00472,10008190,56,10703,35,4277,0.047139396,0.639392876,0.411143785,1.006686859,0.119727415,DB0047210008190_,2.122537659,-0.447236184,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,127065,DB00115,10013887,40,18385,25,10447,0.700294873,0.909180917,0.537870849,1.564600247,0.819879108,DB0011510013887_,0.198598379,-0.095211176,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,127067,DB00472,10013887,40,10719,20,4292,0.473989545,0.800806916,0.456628827,1.447708703,0.63978996,DB0047210013887_,0.446615344,-0.222135414,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,127070,DB00641,10013887,42,14082,33,12442,0.644454124,1.124487042,0.695355513,1.832419353,0.780476932,DB0064110013887_,0.247850094,0.117326969,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,127072,DB00678,10013887,31,15568,29,10695,0.238684578,0.734385161,0.427864751,1.263735053,0.396392387,DB0067810013887_,0.925350682,-0.308721646,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,losartan,DB00678
,127073,DB00761,10013887,37,15270,21,8604,1,0.992757832,0.565675184,1.786228571,1,DB0076110013887_,0,-0.00726852,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,127090,DB00472,10033295,137,10622,109,4203,1.54326578940823e-07,0.497340714,0.382875611,0.647319835,2.69443648452975e-06,DB0047210033295_,12.82432147,-0.698479947,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,127093,DB00761,10033295,51,15256,23,8602,0.398620867,1.250288471,0.749710411,2.145051506,0.568438871,DB0076110033295_,0.564861498,0.223374301,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,127122,DB13961,10067482,36,9421,18,6396,0.331957763,1.35779157,0.750352513,2.542330811,0.500760986,DB1396110067482_,0.691626365,0.305859534,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,127128,DB00327,10020751,44,6094,18,4244,0.068952423,1.702280757,0.962121515,3.134717921,0.159431249,DB0032710020751_,1.836142489,0.531968973,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,hydromorphone,DB00327
,127133,DB00349,10041962,29,993,34,910,0.370664689,0.781749114,0.455455518,1.333903931,0.540357802,DB0034910041962_,0.615523763,-0.246221416,NA,10041962,Status epilepticus,10029205,Nervous system disorders,Nerv,clobazam,DB00349
,127141,DB00864,10009657,42,6827,47,8345,0.748762999,1.092308023,0.702057265,1.69462124,0.857439407,DB0086410009657_,0.153804764,0.08829291,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,127142,DB01015,10009657,38,9849,27,9354,0.265093805,1.33664908,0.7942516,2.278412589,0.427054484,DB0101510009657_,0.850843676,0.290165796,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,127148,DB00005,10071553,53,128029,11,42408,0.19238264,1.595907533,0.82378838,3.388670562,0.339620384,DB0000510071553_,1.079926803,0.467442561,NA,10071553,Nasal discharge discolouration,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,127164,DB01164,10000059,86,6438,113,7823,0.615968113,0.924771103,0.688938747,1.237683897,0.757244868,DB0116410000059_,0.278068607,-0.078209028,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,calcium chloride,DB01164
,127168,DB04861,10000081,23,1942,30,1357,0.024925748,0.535834871,0.295834225,0.958713406,0.073318406,DB0486110000081_,2.6129436,-0.623929241,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,nebivolol,DB04861
,127173,DB01211,10012735,52,1600,27,760,0.714616022,0.914851294,0.559125294,1.527694649,0.830822547,DB0121110012735_,0.185339048,-0.088993747,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,clarithromycin,DB01211
,127174,DB04861,10013573,77,1888,43,1344,0.220878882,1.274642901,0.860412613,1.909721076,0.374555751,DB0486110013573_,0.982014619,0.242666062,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,nebivolol,DB04861
,127180,DB01211,10028813,81,1571,25,762,0.055630886,1.571265682,0.98332916,2.590772291,0.135419708,DB0121110028813_,1.999376379,0.451881461,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,clarithromycin,DB01211
,127186,DB00177,10047700,131,4669,48,2802,0.003680673,1.637751119,1.163953268,2.337787952,0.015956869,DB0017710047700_,4.137865891,0.493324032,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,valsartan,DB00177
,127188,DB01211,10047700,51,1601,15,772,0.108889954,1.639173035,0.90034677,3.159659206,0.224369728,DB0121110047700_,1.494460015,0.494191868,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,clarithromycin,DB01211
,127191,DB00331,10016825,128,24818,51,20701,3.79541114348086e-06,2.093385213,1.501234225,2.957483288,4.63795359862364e-05,DB0033110016825_,9.978652231,0.738782475,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,metformin,DB00331
,127195,DB00196,10008531,36,5047,37,3248,0.053531619,0.62621415,0.383690433,1.021022132,0.131622636,DB0019610008531_,2.02781627,-0.468062873,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,127203,DB00028,10046306,315,13143,109,5506,0.094751438,1.210643004,0.968345137,1.523005111,0.202887177,DB0002810046306_,1.595105231,0.191151627,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,127221,DB06655,10003988,46,3642,27,2092,1,0.978616274,0.593663651,1.642374548,1,DB0665510003988_,0,-0.02161567,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,liraglutide,DB06655
,127223,DB06655,10010774,80,3608,51,2068,0.582134116,0.899110502,0.62220793,1.309448997,0.730289714,DB0665510010774_,0.314313955,-0.106349335,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,liraglutide,DB06655
,127225,DB06655,10013573,75,3613,38,2081,0.555045171,1.13679229,0.756483708,1.733331247,0.70854823,DB0665510013573_,0.344537149,0.128210515,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,liraglutide,DB06655
,127235,DB00331,10048561,27,24919,30,20722,0.28901765,0.748427015,0.427944347,1.303046655,0.454138506,DB0033110048561_,0.789353047,-0.289781588,NA,10048561,Stent placement,10042613,Surgical and medical procedures,Surg,metformin,DB00331
,127243,DB00331,10060820,34,24912,21,20731,0.343018951,1.347310917,0.759500736,2.44368673,0.512345331,DB0033110060820_,0.668756407,0.298110693,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,127267,DB00186,10038687,61,16840,38,9970,0.835197744,0.950393418,0.623160398,1.466037333,0.914696473,DB0018610038687_,0.089162992,-0.050879256,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,127269,DB01075,10038687,57,19891,34,11063,0.743495301,0.932424438,0.598936981,1.471653844,0.853340349,DB0107510038687_,0.158596809,-0.069967162,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,127272,DB00950,10046306,73,4645,18,2038,0.028768793,1.77924693,1.047831987,3.176370067,0.08196829,DB0095010046306_,2.501422819,0.576190202,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,fexofenadine,DB00950
,127273,DB00983,10046306,41,3460,11,1729,0.075097016,1.862363177,0.937232104,4.028409332,0.169997421,DB0098310046306_,1.771972013,0.621846207,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,formoterol,DB00983
,127276,DB00678,10005425,53,15546,27,10697,0.21213911,1.350673471,0.833904318,2.234961521,0.363938029,DB0067810005425_,1.010771676,0.300603336,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,losartan,DB00678
,127286,DB00678,10043414,38,15561,20,10704,0.352352335,1.306946123,0.74113724,2.372183036,0.522088059,DB0067810043414_,0.649919009,0.267693212,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,127296,DB00482,10020751,90,8169,23,3048,0.111206177,1.459927113,0.913266644,2.424001894,0.227891815,DB0048210020751_,1.478884258,0.378386512,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,celecoxib,DB00482
,127297,DB00482,10046735,146,8113,37,3034,0.035893997,1.475547003,1.01992665,2.183435435,0.09732193,DB0048210046735_,2.329730929,0.38902877,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,celecoxib,DB00482
,127305,DB00836,10013911,42,5493,38,4037,0.365211068,0.812319737,0.510174933,1.297128744,0.534854672,DB0083610013911_,0.625760211,-0.207861252,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,127307,DB08908,10028836,40,10633,11,3268,0.869042666,1.117608862,0.56200155,2.417975362,0.941754638,DB0890810028836_,0.060010508,0.111191458,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,dimethyl fumarate,DB08908
,127310,DB00126,10040829,52,10119,19,5926,0.084464925,1.602735149,0.930692141,2.873571235,0.185834146,DB0012610040829_,1.682900689,0.471711638,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,ascorbic acid,DB00126
,127311,DB01101,10040829,206,7383,46,3862,2.62455180708747e-08,2.342399926,1.69003335,3.307082316,5.36649896921775e-07,DB0110110040829_,14.43791992,0.851176013,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,capecitabine,DB01101
,127312,DB01234,10040829,187,31438,99,32789,2.73349729563878e-08,1.970027071,1.535175738,2.541078767,5.55899237260081e-07,DB0123410040829_,14.40267879,0.678047284,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,127325,DB08875,10012174,25,618,56,1187,0.631914493,0.85750991,0.507411432,1.413100238,0.770695641,DB0887510012174_,0.260461743,-0.153722543,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,cabozantinib,DB08875
,127330,DB00207,10029331,69,9011,70,5385,0.002014559,0.589113946,0.41551253,0.835001492,0.009785759,DB0020710029331_,4.626827101,-0.529135658,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,127331,DB00950,10029331,47,4671,32,2024,0.063884222,0.636472685,0.396321707,1.034026298,0.150452181,DB0095010029331_,1.894109982,-0.451813777,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,fexofenadine,DB00950
,127355,DB00404,10061284,64,19828,15,9847,0.007996596,2.11886914,1.193188515,4.006036995,0.029774378,DB0040410061284_,3.514107064,0.750882522,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,127363,DB00165,10013709,78,2067,60,1306,0.285167436,0.821438032,0.574751789,1.178809262,0.449769047,DB0016510013709_,0.799021057,-0.196698777,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pyridoxine,DB00165
,127366,DB00215,10048393,95,11008,8,5268,4.13324108826344e-09,5.682902581,2.767039792,13.55780914,1.0110957841322e-07,DB0021510048393_,16.10706097,1.73746212,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,127367,DB00999,10048393,114,21316,20,12219,6.21317794865705e-08,3.26731848,2.018607004,5.552949482,1.17665635117811e-06,DB0099910048393_,13.65283374,1.183969612,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,127368,DB06413,10048393,45,1511,10,664,0.053075923,1.97697781,0.974774911,4.42687088,0.13076821,DB0641310048393_,2.034328916,0.68156932,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,armodafinil,DB06413
,127371,DB00169,10047461,144,38547,60,18115,0.452995166,1.127862219,0.828568206,1.551670452,0.620591455,DB0016910047461_,0.477082296,0.120324,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,127372,DB00635,10047461,128,32925,57,23737,0.002163054,1.618939676,1.175471214,2.253737302,0.010377055,DB0063510047461_,4.568158191,0.481771414,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,127374,DB08932,10047461,132,19311,37,6560,0.329708976,1.211897819,0.835028327,1.797711356,0.498369731,DB0893210047461_,0.696413045,0.192187576,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,127375,DB00668,10050584,73,10018,13,4290,0.001983402,2.404552409,1.320568042,4.735036153,0.009660655,DB0066810050584_,4.639693798,0.877363778,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,epinephrine,DB00668
,127376,DB13961,10050584,101,9356,42,6372,0.007745959,1.637737001,1.13036717,2.410144819,0.029027414,DB1396110050584_,3.539514579,0.493315411,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,fish oil,DB13961
,127401,DB00005,10006811,169,127913,27,42392,0.000181727,2.074261618,1.376106708,3.240667203,0.001330369,DB0000510006811_,6.622298812,0.729605244,NA,10006811,Bursitis,10028395,Musculoskeletal and connective tissue disorders,Musc,etanercept,DB00005
,127405,DB00331,10003285,90,24856,48,20704,0.012853839,1.561777312,1.087802233,2.266799656,0.043486318,DB0033110003285_,3.135308914,0.445824475,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,127408,DB00695,10003285,108,27941,44,20484,0.000941008,1.799438164,1.255663573,2.617848587,0.005239227,DB0069510003285_,5.251581317,0.587474485,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,127418,DB00542,10013709,63,1623,67,1357,0.207919798,0.78625467,0.544062803,1.135040464,0.358754496,DB0054210013709_,1.025116979,-0.240474531,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,benazepril,DB00542
,127419,DB00763,10013709,51,719,13,288,0.196112231,1.570810386,0.826567139,3.197835835,0.344388695,DB0076310013709_,1.065984331,0.451591656,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,methimazole,DB00763
,127423,DB00542,10025482,58,1628,30,1394,0.029539881,1.655181982,1.040907294,2.6808559,0.083705884,DB0054210025482_,2.480446005,0.503910962,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,benazepril,DB00542
,127425,DB00916,10025482,101,5222,27,2404,0.01218551,1.721979397,1.113305585,2.747733528,0.041660143,DB0091610025482_,3.178210423,0.543474442,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,127436,DB00268,10053762,105,2870,42,1503,0.157521707,1.309172358,0.901727555,1.930664499,0.294202441,DB0026810053762_,1.223487172,0.26939515,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ropinirole,DB00268
,127449,DB00451,10016970,116,47155,9,15410,6.38118234474291e-07,4.21204313,2.142955432,9.443996806,9.60649358141853e-06,DB0045110016970_,11.55307127,1.437947834,female,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,127464,DB00722,10041569,38,25365,30,26002,0.331755471,1.298466263,0.783139266,2.170892495,0.500585107,DB0072210041569_,0.691977651,0.26118377,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,127466,DB00996,10041569,66,38887,34,22391,0.67783037,1.117737043,0.728015705,1.744474469,0.804755555,DB0099610041569_,0.217216706,0.111306144,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,127469,DB00390,10062355,58,4087,18,3283,0.00026631,2.587980436,1.499697078,4.6778138,0.001831248,DB0039010062355_,6.302757598,0.950877817,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,127470,DB00722,10062355,135,25268,94,25938,0.004301387,1.474231911,1.123943123,1.940436084,0.018120922,DB0072210062355_,4.010688118,0.388137116,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,127471,DB01137,10062355,36,7736,29,5564,0.705787174,0.892852164,0.531583758,1.511580771,0.823674283,DB0113710062355_,0.193980115,-0.113334261,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,127473,DB06228,10047513,60,15852,32,16044,0.003290753,1.897661118,1.215132336,3.014147725,0.014585184,DB0622810047513_,4.227749069,0.640622137,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,rivaroxaban,DB06228
,127476,DB00374,10022076,45,17671,17,5707,0.556346335,0.854923101,0.479327805,1.594613614,0.709761129,DB0037410022076_,0.342826803,-0.156743754,NA,10022076,Injection site infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,127479,DB01261,10033425,94,3687,48,3255,0.002130715,1.728743167,1.204260631,2.509810308,0.010250908,DB0126110033425_,4.580388963,0.547394652,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sitagliptin,DB01261
,127481,DB08868,10052904,93,9109,37,2474,0.05326243,0.682694169,0.460425147,1.030948315,0.131112844,DB0886810052904_,2.031696926,-0.381708295,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,fingolimod,DB08868
,127504,DB00112,10042772,57,5876,28,4063,0.150352237,1.407561133,0.8788329,2.302549985,0.284429707,DB0011210042772_,1.257269133,0.341858514,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,bevacizumab,DB00112
,127505,DB00115,10042772,127,18298,103,10369,0.008718198,0.698750241,0.533954109,0.91619064,0.031916132,DB0011510042772_,3.444643705,-0.35846191,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,127506,DB00544,10042772,26,2409,35,2618,0.441017471,0.807340769,0.465199428,1.384739857,0.609222901,DB0054410042772_,0.495571067,-0.214009434,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,fluorouracil,DB00544
,127507,DB01273,10035664,41,1999,14,1261,0.050225782,1.847071916,0.981573971,3.68413626,0.125422604,DB0127310035664_,2.076066408,0.613601637,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,varenicline,DB01273
,127509,DB00563,10053156,70,46576,26,15322,0.635819706,0.88566938,0.55716715,1.448322241,0.773634813,DB0056310053156_,0.256655335,-0.121411558,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,127511,DB00697,10008479,78,6018,17,1789,0.270624631,1.363903728,0.797183378,2.465904443,0.433317912,DB0069710008479_,0.836283612,0.310350976,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,127512,DB00868,10008479,55,2929,16,1630,0.023862325,1.912741432,1.075925067,3.588510448,0.070912518,DB0086810008479_,2.646308307,0.648537518,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,benzonatate,DB00868
,127513,DB01212,10008479,38,1981,19,1922,0.022486849,1.940111065,1.086626702,3.576379828,0.067697496,DB0121210008479_,2.692706085,0.662745222,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ceftriaxone,DB01212
,127514,DB00215,10061024,44,11059,27,5249,0.309243873,0.773522435,0.467868087,1.300590259,0.476631594,DB0021510061024_,0.741011425,-0.256800605,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,citalopram,DB00215
,127518,DB00727,10061024,49,3794,61,4112,0.501985743,0.870622201,0.583688964,1.292763512,0.66335002,DB0072710061024_,0.410452494,-0.13854715,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,nitroglycerin,DB00727
,127524,DB01222,10061024,34,9240,25,5380,0.417408176,0.791887753,0.458181546,1.386105901,0.586524192,DB0122210061024_,0.533541364,-0.233335623,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,budesonide,DB01222
,127538,DB00656,10006784,60,11953,17,6602,0.01225014,1.949336183,1.12132755,3.566773064,0.041844696,DB0065610006784_,3.173790239,0.667488895,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,127539,DB01076,10006784,122,25625,62,25521,1.13388511677993e-05,1.959719692,1.431325683,2.706565359,0.000121057,DB0107610006784_,9.019251166,0.672801449,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,127541,DB00656,10016322,212,11801,92,6527,0.05337613,1.274518138,0.991288779,1.649214704,0.131347805,DB0065610016322_,2.029906471,0.242568176,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,127552,DB00563,10003997,51,46595,53,15295,8.96337068666634e-09,0.315852926,0.21065968,0.473194952,2.03808130189468e-07,DB0056310003997_,15.40608682,-1.152478596,male,10003997,Bacteraemia,10021881,Infections and infestations,Infec,methotrexate,DB00563
,127555,DB00773,10003997,33,2290,46,2781,0.570836116,0.871236131,0.537710924,1.397688272,0.721268016,DB0077310003997_,0.326744482,-0.137842236,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,etoposide,DB00773
,127560,DB00381,10016334,84,29276,36,22851,0.002268474,1.821219664,1.218271917,2.772397155,0.010779508,DB0038110016334_,4.530108356,0.599506422,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,127567,DB00804,10020772,57,2943,10,889,0.142147776,1.721548275,0.866747398,3.797151362,0.272796282,DB0080410020772_,1.299029981,0.543224046,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,dicyclomine,DB00804
,127569,DB00804,10021097,56,2944,17,882,1,0.986895552,0.561615768,1.8214937,1,DB0080410021097_,0,-0.013191068,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,dicyclomine,DB00804
,127571,DB00804,10037660,76,2924,16,883,0.211800444,1.434276517,0.823734977,2.649523551,0.363582462,DB0080410037660_,1.011749151,0.360660553,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,dicyclomine,DB00804
,127573,DB14500,10037660,174,7635,88,3985,0.843668116,1.03201317,0.79167912,1.353271688,0.920827008,DB1450010037660_,0.082483091,0.031511428,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,127597,DB00343,10028411,137,8599,35,5060,3.22328433372207e-06,2.303198551,1.576234185,3.44723897,4.03277518709441e-05,DB0034310028411_,10.11847069,0.834298831,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,diltiazem,DB00343
,127599,DB00471,10049848,88,14101,23,5442,0.110531885,1.476510836,0.923307054,2.45200605,0.226854893,DB0047110049848_,1.483444705,0.389681761,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,127602,DB00476,10061422,37,17220,34,6143,0.000114456,0.388230914,0.236809387,0.638228124,0.000895716,DB0047610061422_,7.017886776,-0.946154977,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,127612,DB00153,10047942,98,7325,38,3401,0.403777199,1.197369786,0.813502086,1.794574185,0.573458526,DB0015310047942_,0.556069662,0.180127306,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,ergocalciferol,DB00153
,127613,DB06643,10047942,283,52138,31,7484,0.171258567,1.310395044,0.901824653,1.966779964,0.312562938,DB0664310047942_,1.162949428,0.270328652,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,denosumab,DB06643
,127619,DB00338,10003983,54,33620,39,22233,0.672986632,0.915652461,0.595173353,1.420251653,0.801533955,DB0033810003983_,0.221227944,-0.088118396,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,127632,DB00333,10041349,68,3003,64,3088,0.660240845,1.092544889,0.762099823,1.567951344,0.792548323,DB0033310041349_,0.2325018,0.088509736,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,methadone,DB00333
,127634,DB08934,10041349,24,4465,60,6144,0.014181922,0.550445634,0.32732526,0.898871327,0.047076064,DB0893410041349_,3.05599061,-0.597027085,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,sofosbuvir,DB08934
,127660,DB00641,10021143,57,14067,60,12415,0.35430429,0.838441284,0.5726011,1.226497524,0.524123492,DB0064110021143_,0.64602795,-0.176210725,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,127662,DB00007,10028372,8,1939,55,4397,0.001389512,0.329896166,0.13542448,0.698327019,0.007216621,DB0000710028372_,4.931368429,-1.108977322,male,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,leuprolide,DB00007
,127682,DB01234,10061394,63,31562,43,32845,0.032667422,1.524653703,1.01810495,2.302707682,0.090566731,DB0123410061394_,2.401668338,0.421767304,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,127683,DB01373,10061394,75,22645,10,7371,0.00510738,2.441330436,1.25577835,5.300931485,0.020811949,DB0137310061394_,3.872227984,0.892543151,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,127706,DB00461,10013709,69,1021,25,300,0.376519028,0.811085409,0.496352298,1.362969383,0.54639224,DB0046110013709_,0.604418172,-0.209381917,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,nabumetone,DB00461
,127708,DB00316,10018304,38,65436,15,36938,0.256008869,1.43003763,0.768401656,2.798888961,0.416781148,DB0031610018304_,0.875194019,0.357700759,NA,10018304,Glaucoma,10015919,Eye disorders,Eye,acetaminophen,DB00316
,127715,DB01050,10031161,66,18042,12,9359,0.000284907,2.852944597,1.527928212,5.801930642,0.001934584,DB0105010031161_,6.247863059,1.048351653,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,127720,DB00916,10044221,37,5286,38,2393,0.000614563,0.440837655,0.271881066,0.714242866,0.003672147,DB0091610044221_,5.606978727,-0.819078601,NA,10044221,Toxic encephalopathy,10029205,Nervous system disorders,Nerv,metronidazole,DB00916
,127732,DB01202,10071066,30,6684,20,5698,0.477582133,1.278698768,0.701671527,2.378418534,0.642915489,DB0120210071066_,0.441741996,0.245842974,NA,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,127778,DB00264,10013496,58,29549,32,24860,0.05684793,1.524867144,0.973557718,2.427416394,0.137522234,DB0026410013496_,1.983969672,0.421907288,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,127780,DB01076,10013496,38,25709,48,25535,0.281874212,0.786314252,0.499694134,1.22948365,0.445832276,DB0107610013496_,0.807812461,-0.240398755,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,127783,DB13961,10016825,64,9393,24,6390,0.012008723,1.814048441,1.117501747,3.036200411,0.04117254,DB1396110016825_,3.189983739,0.595561055,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,fish oil,DB13961
,127819,DB00264,10057668,67,29540,53,24839,0.783490927,1.06298942,0.730006805,1.554597749,0.882171087,DB0026410057668_,0.125369266,0.061085146,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,127823,DB13961,10057668,42,9415,27,6387,0.902391549,1.055270051,0.634830562,1.781860011,0.957195726,DB1396110057668_,0.043747388,0.053796707,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,127854,DB00019,10016825,41,18971,14,9515,0.252698868,1.468821112,0.783914474,2.918839738,0.412955935,DB0001910016825_,0.884414387,0.384460115,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,pegfilgrastim,DB00019
,127869,DB01065,10024855,40,4291,30,3021,0.80817729,0.938721346,0.56876838,1.564464718,0.896477889,DB0106510024855_,0.10928165,-0.0632366,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,melatonin,DB01065
,127871,DB01065,10033295,31,4300,21,3030,1,1.040198275,0.57765654,1.908549487,1,DB0106510033295_,0,0.039411344,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,melatonin,DB01065
,127872,DB06403,10033295,45,21426,8,6653,0.194017381,1.746534193,0.814315809,4.292272011,0.341725927,DB0640310033295_,1.073746247,0.557633363,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,ambrisentan,DB06403
,127875,DB00695,10035669,37,28012,63,20465,3.98474614559592e-05,0.429075181,0.277794565,0.654316374,0.000363299,DB0069510035669_,7.920284842,-0.846123128,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,furosemide,DB00695
,127888,DB00374,10035759,32,17684,21,5703,0.015246764,0.491419303,0.274527394,0.897468577,0.049948425,DB0037410035759_,2.996764306,-0.710457539,NA,10035759,Pneumothorax,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,127894,DB00370,10038695,37,4504,36,3627,0.478295524,0.827675377,0.507626034,1.350727246,0.643595671,DB0037010038695_,0.44068459,-0.189134258,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mirtazapine,DB00370
,127895,DB01065,10038695,40,4291,47,3004,0.020911778,0.59586233,0.379832208,0.930785728,0.064026336,DB0106510038695_,2.748460787,-0.517745628,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,melatonin,DB01065
,127896,DB00370,10043607,23,4518,33,3630,0.042099151,0.560030713,0.313366803,0.984971852,0.109893857,DB0037010043607_,2.208240318,-0.579763652,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,mirtazapine,DB00370
,127904,DB00338,10049414,86,33588,60,22212,0.799632406,0.947888582,0.673483262,1.341522656,0.891684355,DB0033810049414_,0.114643071,-0.053518314,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,127908,DB00374,10053405,45,17671,11,5713,0.53291617,1.322554992,0.672942068,2.837667724,0.689694807,DB0037410053405_,0.371506088,0.279565466,NA,10053405,Brain natriuretic peptide increased,10022891,Investigations,Inv,treprostinil,DB00374
,127910,DB00695,10053405,48,28001,25,20503,0.192200007,1.405858839,0.849469942,2.380117755,0.339434756,DB0069510053405_,1.080473527,0.340648389,NA,10053405,Brain natriuretic peptide increased,10022891,Investigations,Inv,furosemide,DB00695
,127920,DB00695,10061422,31,28018,31,20497,0.247093956,0.731579831,0.429952022,1.244786703,0.406233715,DB0069510061422_,0.900826632,-0.312548931,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,127926,DB01065,10068319,42,4289,8,3043,0.000146664,3.724251776,1.724128058,9.1971186,0.001105238,DB0106510068319_,6.80769433,1.314865966,female,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,melatonin,DB01065
,127929,DB00005,10051060,99,127983,28,42391,0.537811095,1.171108168,0.763096637,1.851340837,0.693928509,DB0000510051060_,0.365386337,0.157950453,NA,10051060,Hip surgery,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,127934,DB00853,10028813,174,1647,191,2075,0.224774567,1.147690462,0.919551584,1.431714674,0.379484841,DB0085310028813_,0.968940628,0.137751629,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,temozolomide,DB00853
,127942,DB01050,10044034,44,18064,28,9343,0.386247655,0.812790502,0.494469308,1.356708245,0.5564244,DB0105010044034_,0.586223966,-0.207281888,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,127944,DB01050,10069327,66,18042,32,9339,0.831244367,1.067598912,0.689288607,1.684577595,0.911753388,DB0105010069327_,0.092385734,0.06541212,NA,10069327,Product quality issue,10077536,Product issues,Prod,ibuprofen,DB01050
,127978,DB00399,10008469,42,6950,15,4983,0.021362622,2.007419966,1.089164929,3.901867399,0.065141128,DB0039910008469_,2.73119916,0.696850298,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,128004,DB01394,10013573,62,1378,42,1961,0.000248236,2.100297102,1.387845662,3.20611261,0.001724578,DB0139410013573_,6.362772963,0.742078812,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,colchicine,DB01394
,128010,DB01394,10047700,56,1384,43,1960,0.003586221,1.843952523,1.209382833,2.828655887,0.015620739,DB0139410047700_,4.159155796,0.611911378,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,colchicine,DB01394
,128026,DB00047,10043071,33,9252,36,8482,0.472243661,0.840386571,0.507289161,1.388059653,0.63827868,DB0004710043071_,0.448980289,-0.173893289,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,insulin glargine,DB00047
,128027,DB00321,10043071,46,7401,24,2826,0.227919691,0.73188429,0.436611547,1.256132347,0.383305229,DB0032110043071_,0.958923664,-0.312132851,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,amitriptyline,DB00321
,128042,DB08895,10005750,337,27777,74,6572,0.613730581,1.077451126,0.834240167,1.407310644,0.755369411,DB0889510005750_,0.280548363,0.074598183,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,tofacitinib,DB08895
,128048,DB08895,10016322,310,27804,59,6587,0.142805532,1.244763148,0.938346604,1.67583047,0.273738808,DB0889510016322_,1.295580881,0.21894527,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,128052,DB00635,10018691,39,33014,20,23774,0.236399015,1.404222144,0.799083008,2.541872537,0.393621032,DB0063510018691_,0.932366681,0.339483515,NA,10018691,Granuloma,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,128057,DB00563,10056342,69,46577,40,15308,0.005314638,0.566946029,0.378449481,0.859555079,0.021476709,DB0056310056342_,3.840786227,-0.567491167,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,128061,DB00650,10051055,14,2117,37,1977,0.000606119,0.353438744,0.175940261,0.671805432,0.003629945,DB0065010051055_,5.618537696,-1.040045092,male,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,leucovorin,DB00650
,128065,DB01041,10061822,50,2995,37,3081,0.132235124,1.390074192,0.887821804,2.194080906,0.258982209,DB0104110061822_,1.350995909,0.329357121,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,thalidomide,DB01041
,128074,DB01240,10036653,85,5666,14,1562,0.083882055,1.673632052,0.941529417,3.199805733,0.184884476,DB0124010036653_,1.688024102,0.514996146,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,epoprostenol,DB01240
,128076,DB01115,10070863,80,3520,58,2210,0.426479883,0.866012885,0.607202465,1.241544185,0.595169829,DB0111510070863_,0.518908487,-0.143855491,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,nifedipine,DB01115
,128078,DB00355,10013968,80,1713,57,1206,1,0.988110942,0.68885466,1.425046797,1,DB0035510013968_,0,-0.011960298,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,aztreonam,DB00355
,128079,DB00355,10028813,49,1744,21,1242,0.064756883,1.661431925,0.972113024,2.932479267,0.152030606,DB0035510028813_,1.883673426,0.507679836,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,aztreonam,DB00355
,128085,DB00682,10013538,61,19398,38,16326,0.15763742,1.351029317,0.886092486,2.083582143,0.294313995,DB0068210013538_,1.223108072,0.300866759,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,warfarin,DB00682
,128091,DB00983,10013700,42,3459,12,1728,0.109047401,1.748314661,0.900770119,3.657828147,0.224616879,DB0098310013700_,1.493359088,0.558652273,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,formoterol,DB00983
,128096,DB00115,10006451,223,18202,84,10388,0.001007594,1.51506902,1.172306675,1.973544138,0.005539553,DB0011510006451_,5.195841517,0.415460995,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,128097,DB13961,10006451,142,9315,58,6356,0.000826762,1.670503069,1.220344303,2.312111283,0.004705702,DB1396110006451_,5.358980389,0.51312482,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,fish oil,DB13961
,128098,DB14513,10006451,103,7074,29,3535,0.005195401,1.774772551,1.163061115,2.786009131,0.021100294,DB1451310006451_,3.858468288,0.573672275,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,magnesium,DB14513
,128106,DB00126,10001551,51,10120,56,5889,0.001209806,0.529966054,0.354892279,0.789850998,0.006445677,DB0012610001551_,5.044345552,-0.634942324,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,ascorbic acid,DB00126
,128108,DB00295,10001551,36,14627,39,9563,0.032805953,0.60353169,0.372498642,0.975340875,0.090859753,DB0029510001551_,2.398438135,-0.50495673,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,morphine,DB00295
,128115,DB00683,10001551,21,1563,32,1606,0.168652596,0.674388759,0.367859562,1.212087399,0.309083736,DB0068310001551_,1.174143048,-0.393948541,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,midazolam,DB00683
,128116,DB00736,10001551,37,10554,22,5531,0.680866954,0.881396854,0.505886757,1.570142619,0.807023985,DB0073610001551_,0.21440189,-0.126247296,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,esomeprazole,DB00736
,128118,DB00818,10001551,31,1389,40,1637,0.719851376,0.913428879,0.549240003,1.506225166,0.834673745,DB0081810001551_,0.180714355,-0.090549761,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,propofol,DB00818
,128120,DB00959,10001551,49,8029,56,4946,0.00170543,0.539062014,0.359107199,0.806803361,0.008529585,DB0095910001551_,4.764214531,-0.617924661,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,methylprednisolone,DB00959
,128122,DB01075,10001551,53,19895,38,11059,0.230201152,0.775314495,0.501199057,1.209616707,0.386172829,DB0107510001551_,0.951470266,-0.254486532,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,diphenhydramine,DB01075
,128131,DB00557,10002034,69,5918,40,3027,0.542038565,0.882338452,0.587659918,1.340561852,0.697329304,DB0055710002034_,0.360497521,-0.125179564,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,hydroxyzine,DB00557
,128133,DB00804,10002034,46,2954,15,884,0.760139501,0.917726346,0.500252974,1.778556226,0.866653659,DB0080410002034_,0.143115853,-0.085856031,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,dicyclomine,DB00804
,128134,DB00829,10002034,57,7995,39,4415,0.33559886,0.807118595,0.526829281,1.248016447,0.504766672,DB0082910002034_,0.683658992,-0.214284664,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,diazepam,DB00829
,128176,DB00126,10003481,44,10127,45,5900,0.010835053,0.569702106,0.366810371,0.884221395,0.037960597,DB0012610003481_,3.271206572,-0.562641675,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,ascorbic acid,DB00126
,128178,DB00295,10003481,37,14626,29,9573,0.528826133,0.83508824,0.499366314,1.408894026,0.686168703,DB0029510003481_,0.376631759,-0.180217883,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,morphine,DB00295
,128186,DB00818,10003481,33,1387,34,1643,0.620732687,1.149676932,0.686214967,1.924159235,0.761218564,DB0081810003481_,0.272834757,0.139480974,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,propofol,DB00818
,128188,DB00959,10003481,40,8038,50,4952,0.000991512,0.492877138,0.316395802,0.763491649,0.005465399,DB0095910003481_,5.209318095,-0.707495349,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,methylprednisolone,DB00959
,128190,DB01075,10003481,63,19885,45,11052,0.22720158,0.778138146,0.52204301,1.168260476,0.382427865,DB0107510003481_,0.961215232,-0.250851205,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,diphenhydramine,DB01075
,128191,DB01109,10003481,31,4381,43,4227,0.130104527,0.695620993,0.422866834,1.132297171,0.25585796,DB0110910003481_,1.363132832,-0.362950318,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,heparin,DB01109
,128280,DB00736,10013990,42,10549,19,5534,0.685896169,1.159616444,0.659023782,2.113321805,0.810409763,DB0073610013990_,0.210215279,0.148089299,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,esomeprazole,DB00736
,128285,DB01015,10013990,33,9854,31,9350,1,1.010069752,0.59917729,1.706845996,1,DB0101510013990_,0,0.01001939,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,sulfamethoxazole,DB01015
,128287,DB01075,10013990,57,19891,32,11065,1,0.9908749,0.631359856,1.580078106,1,DB0107510013990_,0,-0.009166989,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,diphenhydramine,DB01075
,128295,DB11089,10013990,45,10130,28,8379,0.241784924,1.329321674,0.810647546,2.214963537,0.399906666,DB1108910013990_,0.916524094,0.284668792,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,docusate,DB11089
,128298,DB00264,10017367,31,29576,24,24868,0.788147908,1.086083039,0.616767556,1.934375863,0.88522456,DB0026410017367_,0.121913926,0.082577682,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,128301,DB00316,10017367,43,65431,26,36927,0.80253223,0.933375212,0.56054489,1.582570151,0.893193872,DB0031610017367_,0.11295162,-0.068948002,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,128334,DB00338,10020635,60,33614,65,22207,0.005985397,0.609852634,0.421926541,0.880196934,0.023619002,DB0033810020635_,3.745703736,-0.494537934,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,128357,DB01060,10020772,84,8503,45,5036,0.647471591,1.105562319,0.759440006,1.628079378,0.782689053,DB0106010020772_,0.245019785,0.100354092,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,amoxicillin,DB01060
,128404,DB00281,10030095,46,11412,26,5645,0.61619454,0.875171956,0.529096358,1.476461338,0.757416114,DB0028110030095_,0.277842489,-0.133334891,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,128405,DB00327,10030095,40,6098,15,4247,0.039534987,1.857111622,1.002208944,3.623862366,0.104724089,DB0032710030095_,2.256426112,0.619022389,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,128416,DB00864,10030095,37,6832,34,8358,0.234107103,1.331269025,0.81194615,2.188994146,0.390971802,DB0086410030095_,0.939119838,0.286132641,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,128417,DB01015,10030095,54,9833,28,9353,0.01045343,1.834362937,1.1405238,3.010184906,0.036866818,DB0101510030095_,3.300443362,0.606697248,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,128419,DB01060,10030095,44,8543,26,5055,1,1.001359541,0.602286036,1.696364146,1,DB0106010030095_,0,0.001358618,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,128420,DB01115,10030095,52,3548,22,2246,0.119562335,1.496160988,0.890028131,2.594559908,0.24069051,DB0111510030095_,1.424243362,0.402902486,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,128433,DB00813,10030124,68,10504,48,10120,0.113110668,1.364852159,0.928463756,2.020188991,0.230733298,DB0081310030124_,1.466492791,0.311046114,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,128435,DB01024,10030124,31,2180,20,2100,0.204393913,1.492976415,0.821315842,2.773182937,0.354397836,DB0102410030124_,1.037335167,0.400771721,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,mycophenolic acid,DB01024
,128436,DB01233,10030124,54,3367,29,1697,0.814918206,0.938513062,0.584614446,1.534683517,0.900648575,DB0123310030124_,0.104640137,-0.063458505,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,128441,DB09020,10030124,43,1911,22,1582,0.077783302,1.617833684,0.941996999,2.852801071,0.174597275,DB0902010030124_,1.745273243,0.481088022,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,bisacodyl,DB09020
,128445,DB00557,10033775,88,5899,25,3042,0.00690407,1.815088236,1.150070587,2.961287837,0.026515704,DB0055710033775_,3.630018129,0.596134082,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,128449,DB00646,10033775,35,3418,15,1985,0.377788734,1.355008665,0.718991454,2.67760363,0.547720732,DB0064610033775_,0.601989736,0.303807849,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,nystatin,DB00646
,128450,DB00804,10033775,48,2952,6,893,0.034375671,2.419732205,1.029302109,6.941897759,0.094160538,DB0080410033775_,2.362754102,0.883656875,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,dicyclomine,DB00804
,128454,DB01060,10033775,77,8510,33,5048,0.137049356,1.384065529,0.907884888,2.152215151,0.265581121,DB0106010033775_,1.325834946,0.325025204,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,amoxicillin,DB01060
,128455,DB01109,10033775,35,4377,18,4252,0.027617833,1.888770618,1.039263533,3.548006309,0.079397873,DB0110910033775_,2.533283704,0.635926151,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,heparin,DB01109
,128467,DB00804,10037087,64,2936,17,882,0.789710326,1.130914602,0.650276665,2.070921279,0.886070728,DB0080410037087_,0.120958503,0.123026688,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,dicyclomine,DB00804
,128468,DB05351,10037087,70,2653,17,1114,0.043005733,1.72879073,1.001122129,3.148666132,0.111700167,DB0535110037087_,2.191937078,0.547422164,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,dexlansoprazole,DB05351
,128570,DB00264,10040752,37,29570,50,24842,0.030905723,0.621693178,0.394979996,0.970564119,0.086716154,DB0026410040752_,2.44511509,-0.47530859,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,metoprolol,DB00264
,128571,DB00281,10040752,29,11429,39,5632,4.49440058143082e-05,0.366450012,0.218316445,0.608755415,0.000403605,DB0028110040752_,7.815072732,-1.003893159,male,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,lidocaine,DB00281
,128596,DB00281,10043554,64,11394,64,5607,9.39396652445094e-05,0.492109448,0.341980297,0.70818845,0.000756149,DB0028110043554_,7.187272297,-0.709054132,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,lidocaine,DB00281
,128600,DB00646,10043554,48,3405,40,1960,0.094322429,0.690823776,0.4427937,1.082796935,0.202261001,DB0064610043554_,1.598196331,-0.369870515,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,nystatin,DB00646
,128601,DB00736,10043554,42,10549,34,5519,0.068765973,0.646274548,0.400930859,1.048757423,0.159091106,DB0073610043554_,1.838278248,-0.436530868,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,esomeprazole,DB00736
,128605,DB00959,10043554,80,7998,80,4922,0.002410325,0.615451535,0.44476173,0.85157753,0.011329647,DB0095910043554_,4.480332349,-0.485399078,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,methylprednisolone,DB00959
,128611,DB09020,10043554,21,1933,30,1574,0.064343868,0.57009373,0.308898413,1.03403025,0.151270388,DB0902010043554_,1.888686394,-0.561954493,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,bisacodyl,DB09020
,128617,DB00804,10046571,79,2921,12,887,0.023006791,1.998713849,1.076307188,4.050809956,0.068919426,DB0080410046571_,2.674817189,0.692503898,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,dicyclomine,DB00804
,128619,DB01024,10046571,41,2170,17,2103,0.003281366,2.337027272,1.293861653,4.401652745,0.014549716,DB0102410046571_,4.230183788,0.848879725,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,mycophenolic acid,DB01024
,128620,DB01109,10046571,132,4280,36,4234,9.87701837513335e-14,3.626412755,2.485594022,5.412449345,5.06076857681053e-12,DB0110910046571_,26.00950275,1.288243938,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,heparin,DB01109
,128621,DB01233,10046571,89,3332,22,1704,0.00155856,2.068608837,1.280166052,3.478238877,0.007933817,DB0123310046571_,4.836621052,0.726876322,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,metoclopramide,DB01233
,128622,DB05351,10046571,57,2666,6,1125,0.000223063,4.008152476,1.72522211,11.40879583,0.001579105,DB0535110046571_,6.450897082,1.388330406,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,dexlansoprazole,DB05351
,128627,DB00126,10047942,192,9979,74,5871,0.002044,1.526453848,1.159102408,2.028074837,0.009897368,DB0012610047942_,4.615486462,0.422947299,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,ascorbic acid,DB00126
,128631,DB00575,10047942,38,5206,24,3805,0.608075167,1.157194434,0.675124322,2.020365296,0.750916409,DB0057510047942_,0.28646094,0.145998485,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,clonidine,DB00575
,128634,DB00646,10047942,58,3395,31,1969,0.740955777,1.085100358,0.687275159,1.742992016,0.851354997,DB0064610047942_,0.160926084,0.081672479,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,nystatin,DB00646
,128637,DB00813,10047942,122,10450,68,10100,0.000251656,1.733973202,1.276818041,2.371644844,0.001745556,DB0081310047942_,6.35068206,0.550415424,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,fentanyl,DB00813
,128639,DB00829,10047942,61,7991,25,4429,0.215783871,1.352335212,0.834952592,2.251670037,0.368339712,DB0082910047942_,0.998749637,0.301832885,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,diazepam,DB00829
,128640,DB00864,10047942,28,6841,32,8360,0.796509415,1.069265165,0.619644746,1.835265849,0.889807667,DB0086410047942_,0.116749944,0.066971651,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,tacrolimus,DB00864
,128641,DB01015,10047942,185,9702,183,9198,0.712542477,0.958401031,0.775435584,1.184637027,0.829078987,DB0101510047942_,0.187439849,-0.042488976,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,128649,DB09020,10047942,31,1923,22,1582,0.677175642,1.159172742,0.646960653,2.110355042,0.804245873,DB0902010047942_,0.217850245,0.147706597,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,bisacodyl,DB09020
,128651,DB11089,10047942,204,9971,131,8276,0.023154757,1.29251077,1.030674438,1.625494166,0.069267945,DB1108910047942_,2.669773032,0.25658666,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,docusate,DB11089
,128659,DB00997,10021036,43,5288,35,3479,0.35475706,0.808310306,0.504195736,1.303872705,0.524586612,DB0099710021036_,0.645144733,-0.212809252,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,doxorubicin,DB00997
,128664,DB00836,10035226,53,5482,58,4017,0.042056033,0.66963344,0.451484761,0.991357491,0.109808566,DB0083610035226_,2.209016739,-0.40102482,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,loperamide,DB00836
,128665,DB00836,10038435,51,5484,32,4043,0.504990967,1.174934122,0.739220711,1.893033698,0.665982016,DB0083610038435_,0.406492612,0.161212079,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,loperamide,DB00836
,128666,DB00836,10038695,56,5479,47,4028,0.547864888,0.875962077,0.582428463,1.32251784,0.70241829,DB0083610038695_,0.353226198,-0.13243248,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loperamide,DB00836
,128699,DB00335,10019974,41,8425,24,5441,0.799272823,1.103280378,0.65016423,1.911186246,0.891581897,DB0033510019974_,0.114757982,0.098287904,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,atenolol,DB00335
,128700,DB00761,10019974,68,15239,27,8598,0.134130514,1.420954022,0.896814384,2.310748225,0.261508341,DB0076110019974_,1.3412891,0.351328493,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,128703,DB00381,10023230,47,29313,30,22857,0.422493803,1.221613108,0.756372795,2.001292912,0.591524426,DB0038110023230_,0.525052302,0.200172205,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,128704,DB08895,10023230,322,27792,68,6578,0.437073434,1.120777761,0.859117551,1.480325185,0.605612821,DB0889510023230_,0.501514407,0.114022874,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,128706,DB06273,10042674,51,5044,11,1399,0.536766329,1.285886046,0.659605789,2.743603569,0.693029219,DB0627310042674_,0.366683118,0.251448011,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,128709,DB00285,10016322,259,10692,72,3646,0.141432283,1.226637137,0.938593265,1.620189741,0.271849913,DB0028510016322_,1.302505157,0.20427639,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,128716,DB01255,10025482,47,2086,27,1551,0.342175502,1.294201024,0.785659924,2.171418297,0.511463354,DB0125510025482_,0.670479341,0.257893535,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,lisdexamfetamine,DB01255
,128720,DB01255,10047700,44,2089,32,1546,1,1.017588467,0.627554569,1.666417492,1,DB0125510047700_,0,0.01743558,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lisdexamfetamine,DB01255
,128723,DB00381,10043528,43,29317,24,22863,0.218088826,1.397229083,0.828812848,2.408066995,0.371261603,DB0038110043528_,0.990848335,0.334491049,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,128732,DB06655,10025482,79,3609,28,2091,0.025678187,1.634564003,1.046127708,2.622672009,0.074990404,DB0665510025482_,2.590395117,0.491376104,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,liraglutide,DB06655
,128760,DB00555,10013754,41,7006,26,3460,0.36179224,0.77882682,0.464261478,1.328452193,0.531535913,DB0055510013754_,0.631984514,-0.249966568,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,128783,DB00230,10012601,142,19532,65,8586,0.820295535,0.960326871,0.710341829,1.310116472,0.904291238,DB0023010012601_,0.100603805,-0.040481561,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,pregabalin,DB00230
,128790,DB00451,10014387,77,47194,35,15384,0.123297407,0.717146351,0.47484656,1.10264882,0.246079904,DB0045110014387_,1.402098983,-0.332475343,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,levothyroxine,DB00451
,128812,DB01097,10002034,49,6216,10,1493,0.742211003,1.176889918,0.587157731,2.612147286,0.852275669,DB0109710002034_,0.159845249,0.162875296,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,leflunomide,DB01097
,128826,DB00688,10003997,36,6454,38,5340,0.348803921,0.78386725,0.482113018,1.272370131,0.518320438,DB0068810003997_,0.657161622,-0.243515597,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,128829,DB00761,10003997,31,15276,35,8590,0.006516086,0.498058015,0.296790114,0.832241871,0.025291688,DB0076110003997_,3.677279462,-0.697038712,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,128831,DB00864,10003997,47,6822,46,8346,0.296941512,1.249966076,0.813399372,1.921839493,0.462785428,DB0086410003997_,0.77049177,0.223116412,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,128834,DB00959,10003997,39,8039,34,4968,0.148388235,0.708906449,0.435374776,1.15935679,0.281778988,DB0095910003997_,1.266632244,-0.344031709,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,128846,DB11089,10003997,16,10159,34,8373,0.001515589,0.387874599,0.199787176,0.722746893,0.007760253,DB1108910003997_,4.858740288,-0.94707319,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,docusate,DB11089
,128906,DB01109,10018852,40,4372,77,4193,0.000361711,0.498254067,0.330416227,0.741195544,0.002357446,DB0110910018852_,6.050176461,-0.696645157,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,heparin,DB01109
,128965,DB00524,10020646,40,1537,20,1324,0.049916757,1.722522872,0.977857146,3.126665957,0.124863148,DB0052410020646_,2.080536955,0.543790002,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,metolazone,DB00524
,129024,DB00601,10035664,25,880,30,881,0.584392531,0.834364575,0.466360583,1.480949673,0.732196848,DB0060110035664_,0.311705883,-0.181084832,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,linezolid,DB00601
,129026,DB01024,10035664,73,2138,65,2055,0.666386293,1.079426304,0.75766278,1.540719732,0.79714036,DB0102410035664_,0.226724505,0.0764297,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,mycophenolic acid,DB01024
,129027,DB01212,10035664,91,1928,76,1865,0.384539726,1.158198962,0.83874249,1.603033539,0.554617504,DB0121210035664_,0.589476586,0.146866179,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ceftriaxone,DB01212
,129029,DB01390,10035664,57,1352,64,1453,0.852827939,0.957161125,0.652559094,1.401114759,0.928030734,DB0139010035664_,0.074690428,-0.043783538,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sodium bicarbonate,DB01390
,129034,DB00281,10038435,66,11392,40,5631,0.302779714,0.815612313,0.541766436,1.24165551,0.469130524,DB0028110038435_,0.756874247,-0.203816143,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,lidocaine,DB00281
,129042,DB00916,10038435,24,5299,37,2394,2.45979583215608e-06,0.293122386,0.167344766,0.504458057,3.17250900138481e-05,DB0091610038435_,10.35840271,-1.227165056,male,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,metronidazole,DB00916
,129043,DB01212,10038435,20,1999,32,1909,0.071128955,0.596942229,0.322342795,1.080484553,0.163264601,DB0121210038435_,1.812383078,-0.51593494,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,ceftriaxone,DB01212
,129044,DB01233,10038435,36,3385,20,1706,0.776224002,0.907199025,0.509494431,1.659314947,0.877982174,DB0123310038435_,0.130128988,-0.09739342,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,metoclopramide,DB01233
,129052,DB00653,10038695,30,1062,36,786,0.057914099,0.616932317,0.363572939,1.040105196,0.139549168,DB0065310038695_,1.96933828,-0.482995958,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium sulfate,DB00653
,129055,DB01024,10038695,47,2164,56,2064,0.274086402,0.800544975,0.528814763,1.207278199,0.43718436,DB0102410038695_,0.827400296,-0.222462565,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolic acid,DB01024
,129062,DB00524,10040047,44,1533,25,1319,0.112157652,1.514097913,0.90092761,2.596635872,0.229305323,DB0052410040047_,1.472700877,0.414819825,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,metolazone,DB00524
,129065,DB01390,10040047,25,1384,38,1479,0.202550402,0.703139666,0.404514484,1.202675505,0.351990831,DB0139010040047_,1.044150153,-0.352199736,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,sodium bicarbonate,DB01390
,129085,DB00959,10044439,40,8038,44,4958,0.009280458,0.560793406,0.355572968,0.882071579,0.033523925,DB0095910044439_,3.395495918,-0.578402702,NA,10044439,Transplant rejection,10021428,Immune system disorders,Immun,methylprednisolone,DB00959
,129086,DB01024,10044439,38,2173,57,2063,0.037421584,0.632990274,0.406572108,0.975724088,0.100425069,DB0102410044439_,2.298343417,-0.457300222,NA,10044439,Transplant rejection,10021428,Immune system disorders,Immun,mycophenolic acid,DB01024
,129109,DB00695,10046543,81,27968,46,20482,0.17797613,1.289542426,0.88679763,1.895061537,0.321298254,DB0069510046543_,1.135385447,0.254287447,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,129111,DB00761,10046543,57,15250,23,8602,0.19968283,1.397882911,0.846966848,2.379341597,0.348690462,DB0076110046543_,1.053570679,0.334958885,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,potassium chloride,DB00761
,129132,DB01097,10046571,115,6150,7,1496,2.44174735185188e-05,3.995857286,1.872831044,10.1828152,0.000236744,DB0109710046571_,8.34853069,1.385258146,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,leflunomide,DB01097
,129133,DB01212,10046571,47,1972,26,1915,0.024303264,1.755188705,1.060060108,2.965447135,0.071958466,DB0121210046571_,2.631666183,0.562576376,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ceftriaxone,DB01212
,129147,DB00695,10047943,95,27954,67,20461,0.87349656,1.0378467,0.750801744,1.441616759,0.944986195,DB0069510047943_,0.05658496,0.037148086,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,furosemide,DB00695
,129151,DB01015,10047943,36,9851,22,9359,0.114533506,1.554594878,0.889354125,2.776241241,0.232930728,DB0101510047943_,1.457014174,0.441214983,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,129185,DB00635,10023547,90,32963,61,23733,0.741713727,1.062288472,0.75868709,1.496079615,0.851946571,DB0063510023547_,0.160231464,0.060425517,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,prednisone,DB00635
,129188,DB00028,10018910,29,13429,35,5580,2.54305728039211e-05,0.34430882,0.202805145,0.580463513,0.00024503,DB0002810018910_,8.31412876,-1.066216291,male,10018910,Haemolysis,10005329,Blood and lymphatic system disorders,Blood,human immunoglobulin g,DB00028
,129198,DB00136,10020947,147,1945,34,1648,1.00284554421413e-13,3.662045758,2.491610211,5.518413554,5.12836481121951e-12,DB0013610020947_,25.99623426,1.298021942,female,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,calcitriol,DB00136
,129205,DB00904,10020947,42,23027,38,14418,0.107577733,0.692070264,0.43528581,1.103478012,0.222538127,DB0090410020947_,1.502656834,-0.36806779,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,129206,DB01373,10020947,137,22583,47,7334,0.731493901,0.94663085,0.674303178,1.349628967,0.843877074,DB0137310020947_,0.169748442,-0.054846072,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,calcium,DB01373
,129217,DB00758,10047571,52,8248,38,10036,0.019105946,1.664997472,1.073743439,2.603125947,0.059608283,DB0075810047571_,2.819960744,0.509823605,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,clopidogrel,DB00758
,129223,DB01225,10025482,99,4945,61,4579,0.013260301,1.502761464,1.07846644,2.108421457,0.044569504,DB0122510025482_,3.110705429,0.407304391,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,129246,DB00215,10055798,42,11061,17,5259,0.675891093,1.174627858,0.653779666,2.203113518,0.803554995,DB0021510055798_,0.218709652,0.16095138,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,citalopram,DB00215
,129268,DB00635,10016334,94,32959,35,23759,0.000637205,1.936006305,1.299919967,2.942750778,0.003789352,DB0063510016334_,5.575560285,0.660627246,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,129295,DB00563,10061160,49,46597,8,15340,0.065257603,2.016249797,0.946766049,4.930442366,0.152891767,DB0056310061160_,1.878025012,0.70123925,NA,10061160,Foot operation,10042613,Surgical and medical procedures,Surg,methotrexate,DB00563
,129296,DB00051,10062244,48,25683,15,11405,0.274835951,1.421046298,0.781818991,2.733280045,0.438074222,DB0005110062244_,0.825366925,0.35139343,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,129308,DB00254,10022437,75,5860,42,3346,1,1.019623066,0.68800005,1.528959206,1,DB0025410022437_,0,0.019433016,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,doxycycline,DB00254
,129312,DB13867,10016173,132,4418,79,2475,0.662400462,0.93605369,0.69973632,1.258903162,0.794197698,DB1386710016173_,0.230422859,-0.066082443,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone,DB13867
,129314,DB00338,10019196,105,33569,46,22226,0.019609038,1.511301056,1.058531308,2.187390893,0.060860026,DB0033810019196_,2.799178708,0.412970906,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,129315,DB00421,10019196,31,8872,22,5230,0.569128652,0.830671459,0.465170222,1.507418591,0.720126441,DB0042110019196_,0.328328469,-0.185520919,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,spironolactone,DB00421
,129320,DB00390,10024855,40,4105,38,3263,0.492075861,0.836743244,0.521823616,1.343787729,0.65501299,DB0039010024855_,0.423100211,-0.178238013,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,digoxin,DB00390
,129321,DB00678,10024855,95,15504,66,10658,1,0.989488916,0.714491014,1.377306331,1,DB0067810024855_,0,-0.010566716,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,losartan,DB00678
,129323,DB01098,10024855,46,8103,34,7175,0.434540812,1.197979982,0.751489778,1.926871295,0.603064493,DB0109810024855_,0.505731134,0.18063679,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,129325,DB00204,10044066,30,934,24,1019,0.272549694,1.363539469,0.764422972,2.456403342,0.435526093,DB0020410044066_,0.83120057,0.31008387,NA,10044066,Torsade de pointes,10007541,Cardiac disorders,Card,dofetilide,DB00204
,129339,DB00482,10013781,47,8212,15,3056,0.669411947,1.166013547,0.639498624,2.248617645,0.7992865,DB0048210013781_,0.224035824,0.153590706,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,celecoxib,DB00482
,129354,DB00433,10011224,134,7522,93,5927,0.380913289,1.135300611,0.86294,1.498922064,0.550937015,DB0043310011224_,0.596134786,0.126897471,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,129355,DB08889,10011224,56,3109,49,3836,0.09253869,1.410015481,0.940766119,2.119427781,0.199285525,DB0888910011224_,1.613016686,0.343600684,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carfilzomib,DB08889
,129358,DB04861,10037660,30,1935,23,1364,0.779902183,0.919471148,0.513859571,1.665354208,0.88017556,DB0486110037660_,0.127633892,-0.083956613,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,nebivolol,DB04861
,129359,DB08889,10037660,107,3058,127,3758,0.841135983,1.035388986,0.789325692,1.356041326,0.918864548,DB0888910037660_,0.084616558,0.034777188,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,129360,DB00338,10063829,60,33614,25,22247,0.058866471,1.58839538,0.980620025,2.644852775,0.141338678,DB0033810063829_,1.956596294,0.462724312,NA,10063829,Device malfunction,10077536,Product issues,Prod,omeprazole,DB00338
,129367,DB00381,10040829,181,29179,70,22817,2.67365000632161e-07,2.021892771,1.525477505,2.705422329,4.40331393584985e-06,DB0038110040829_,12.33315313,0.704034088,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,129376,DB09020,10018884,30,1924,25,1579,1,0.984824708,0.557340359,1.754161348,1,DB0902010018884_,0,-0.015291615,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,bisacodyl,DB09020
,129387,DB01050,10055798,58,18050,55,9316,0.001397764,0.544263395,0.369485442,0.802619736,0.007250166,DB0105010055798_,4.926730886,-0.608321967,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,ibuprofen,DB01050
,129390,DB11089,10055798,52,10123,37,8370,0.522823345,1.162021573,0.747006185,1.823962185,0.681261731,DB1108910055798_,0.383808714,0.150161224,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,docusate,DB11089
,129402,DB01202,10001551,30,6684,23,5695,0.782913309,1.111313376,0.623378689,2.005963978,0.881806742,DB0120210001551_,0.12578236,0.105542537,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,levetiracetam,DB01202
,129408,DB01202,10003481,31,6683,24,5694,0.787010037,1.100474521,0.624347723,1.962025283,0.884476968,DB0120210003481_,0.122758806,0.09574147,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,levetiracetam,DB01202
,129410,DB00313,10021097,66,1173,50,1467,0.009812626,1.650513784,1.116016482,2.453969327,0.035039378,DB0031310021097_,3.351282755,0.501086624,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,valproic acid,DB00313
,129420,DB00313,10027417,15,1224,37,1480,0.0234717,0.490323926,0.24874547,0.920383881,0.069973192,DB0031310027417_,2.659643089,-0.712689034,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,valproic acid,DB00313
,129426,DB01275,10033295,10,3969,50,3299,2.00310686005101e-09,0.166287107,0.075069627,0.332416672,5.23735857028351e-08,DB0127510033295_,16.76486346,-1.794039422,male,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,hydralazine,DB01275
,129446,DB01174,10070863,69,870,59,733,1,0.985336014,0.67592124,1.440129609,1,DB0117410070863_,0,-0.014772565,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,phenobarbital,DB01174
,129456,DB08932,10047513,163,19280,49,6548,0.476724558,1.129771229,0.815252156,1.590399157,0.642116835,DB0893210047513_,0.442985006,0.12201516,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,macitentan,DB08932
,129471,DB00788,10030095,50,9306,15,5046,0.049897551,1.807368339,0.997395389,3.468861318,0.124821044,DB0078810030095_,2.080874214,0.591871831,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,129479,DB00188,10038428,24,7862,36,8792,0.300723579,0.7455415,0.425119798,1.285803294,0.467004566,DB0018810038428_,0.761416244,-0.293644479,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,bortezomib,DB00188
,129482,DB05259,10057668,61,11209,15,2713,1,0.984286786,0.551684439,1.867725935,1,DB0525910057668_,0,-0.015837975,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,129490,DB01033,10002034,45,1137,57,1247,0.54378497,0.865902457,0.567456863,1.314509781,0.698926086,DB0103310002034_,0.358210284,-0.143983013,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,mercaptopurine,DB01033
,129509,DB00051,10024570,45,25686,16,11404,0.490205588,1.248654779,0.692016593,2.367740421,0.653503053,DB0005110024570_,0.425408074,0.222066795,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,129510,DB00395,10013968,58,2126,22,714,0.603826509,0.885452281,0.529237395,1.530838656,0.747337482,DB0039510013968_,0.291238412,-0.121656713,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carisoprodol,DB00395
,129516,DB08932,10053762,115,19328,48,6549,0.240022772,0.81178239,0.574138841,1.16335374,0.397868721,DB0893210053762_,0.921633174,-0.208522967,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,129517,DB00559,10067482,38,9621,48,3258,2.2749787468948e-09,0.268122259,0.170122997,0.419910446,5.86828423573405e-08,DB0055910067482_,16.65111845,-1.316312211,male,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,129521,DB00112,10014801,53,5880,47,4044,0.220284656,0.775582611,0.512613479,1.176632994,0.373789237,DB0011210014801_,0.984063177,-0.254140776,NA,10014801,Endophthalmitis,10021881,Infections and infestations,Infec,bevacizumab,DB00112
,129522,DB08932,10039101,286,19157,73,6524,0.027812133,1.334192846,1.026797077,1.752590815,0.079808069,DB0893210039101_,2.528130662,0.2883265,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,129535,DB00182,10071134,49,5145,27,2825,1,0.996472756,0.609216895,1.661990332,1,DB0018210071134_,0,-0.00353348,NA,10071134,Product physical issue,10077536,Product issues,Prod,amphetamine,DB00182
,129536,DB05259,10001760,105,11165,7,2721,0.000105395,3.655426772,1.71035117,9.3244583,0.000834934,DB0525910001760_,7.088158035,1.29621285,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,glatiramer,DB05259
,129590,DB00795,10001760,86,4483,6,1497,7.61060048058779e-06,4.785621529,2.104914155,13.43011166,8.54144095593655e-05,DB0079510001760_,9.367995741,1.565615908,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,sulfasalazine,DB00795
,129591,DB00795,10017944,98,4471,19,1484,0.030455739,1.711772427,1.035645952,2.974810129,0.085673064,DB0079510017944_,2.457216811,0.537529341,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,sulfasalazine,DB00795
,129592,DB01097,10017944,117,6148,22,1481,0.329906806,1.281062357,0.804134538,2.130063012,0.498568412,DB0109710017944_,0.696014463,0.2476897,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,leflunomide,DB01097
,129593,DB00795,10028813,298,4271,78,1425,0.064301158,1.274629053,0.982644042,1.669395352,0.1511835,DB0079510028813_,1.88926095,0.242655198,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sulfasalazine,DB00795
,129595,DB00009,10013968,56,1295,66,1485,0.926240295,0.972978053,0.663599109,1.422482023,0.968656741,DB0000910013968_,0.031844971,-0.027393753,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alteplase,DB00009
,129597,DB08931,10047513,63,6514,20,2426,0.620152409,1.173124749,0.698045439,2.053349196,0.760702152,DB0893110047513_,0.273513388,0.159670914,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,riociguat,DB08931
,129598,DB08932,10000087,503,18940,130,6467,0.004732767,1.321102018,1.084947724,1.618167356,0.019570641,DB0893210000087_,3.93372475,0.27846625,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,129616,DB00007,10020642,8,1939,43,4409,0.021389307,0.423088901,0.171464873,0.912608007,0.065203589,DB0000710020642_,2.730240773,-0.860172954,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,leuprolide,DB00007
,129636,DB00497,10050256,35,19232,23,16352,0.35856906,1.293847112,0.7428547,2.294540377,0.528276876,DB0049710050256_,0.638134747,0.257620038,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,129658,DB00698,10037844,109,3039,9,420,0.1509891,1.673592614,0.841306399,3.786480442,0.28526494,DB0069810037844_,1.254336915,0.514972582,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,nitrofurantoin,DB00698
,129659,DB00213,10072268,38,18857,15,13406,0.051717502,1.80098429,0.967351479,3.525507317,0.128274267,DB0021310072268_,2.053584595,0.588333343,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,pantoprazole,DB00213
,129661,DB00540,10037844,50,2433,15,1076,0.221577984,1.474039938,0.810101753,2.83932108,0.375450591,DB0054010037844_,0.979628397,0.388006889,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,nortriptyline,DB00540
,129668,DB00682,10037884,76,19383,42,16322,0.032843926,1.52373917,1.031364912,2.278415111,0.090950546,DB0068210037884_,2.397439366,0.421167294,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,129669,DB08932,10037884,87,19356,11,6586,0.000682356,2.691184987,1.431041201,5.592795353,0.004006194,DB0893210037884_,5.519913632,0.989981612,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,macitentan,DB08932
,129678,DB01101,10020937,146,7443,65,3843,0.341045582,1.159713991,0.857717359,1.582595845,0.51026771,DB0110110020937_,0.67281977,0.148173415,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,capecitabine,DB01101
,129679,DB00887,10021097,118,2223,91,1724,1,1.005629232,0.752784788,1.346928046,1,DB0088710021097_,0,0.005613447,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,bumetanide,DB00887
,129680,DB00887,10046571,63,2278,27,1788,0.009567008,1.831163322,1.143986208,3.00341812,0.034372446,DB0088710046571_,3.370500018,0.60495146,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,bumetanide,DB00887
,129681,DB00230,10064355,57,19617,26,8625,0.905104739,0.963891152,0.595768529,1.598309506,0.957698934,DB0023010064355_,0.043221816,-0.036776903,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,129742,DB00381,10039073,157,29203,49,22838,3.1691635574819e-09,2.505641095,1.806586273,3.529446736,7.96381110023056e-08,DB0038110039073_,16.34577308,0.918544628,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,129743,DB00999,10039073,195,21235,44,12195,1.77809859449099e-09,2.545073714,1.825486069,3.618150475,4.69250216427668e-08,DB0099910039073_,16.87471479,0.934159614,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,129745,DB00398,10033371,31,696,63,1475,0.910198136,1.042780369,0.649143725,1.644851492,0.959573168,DB0039810033371_,0.04126671,0.041890578,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sorafenib,DB00398
,129747,DB00398,10048959,18,709,65,1473,0.041446611,0.575454609,0.318698536,0.990971559,0.108632813,DB0039810048959_,2.219781775,-0.552594925,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sorafenib,DB00398
,129750,DB00588,10062355,112,16412,56,8412,0.934889426,1.025103248,0.736503884,1.440878321,0.975219008,DB0058810062355_,0.025093209,0.024793338,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,129755,DB06605,10028411,154,13919,117,12916,0.112114251,1.221380916,0.952977215,1.568787293,0.22923442,DB0660510028411_,1.47301013,0.199982117,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,129756,DB06605,10040829,43,14030,27,13006,0.120136057,1.476328716,0.891128232,2.486120877,0.241563279,DB0660510040829_,1.420623817,0.389558409,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,apixaban,DB06605
,129761,DB01020,10037844,40,1773,33,1845,0.345934651,1.26126164,0.771692237,2.074270734,0.515351232,DB0102010037844_,0.662906608,0.232112522,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,isosorbide mononitrate,DB01020
,129763,DB00177,10046735,45,4755,25,2825,0.901267582,1.069398751,0.640324434,1.823917582,0.956927891,DB0017710046735_,0.044027239,0.067096576,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,valsartan,DB00177
,129764,DB00437,10046735,53,6868,60,11486,0.040749673,1.477195882,1,2.176794681,0.107131941,DB0043710046735_,2.233694108,0.390145616,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,129766,DB01104,10046735,164,15299,28,7258,3.6393963869898e-08,2.778585086,1.850929946,4.314751221,7.22519139214705e-07,DB0110410046735_,14.14052193,1.021941836,female,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,sertraline,DB01104
,129767,DB01136,10046735,64,9820,44,11071,0.01184801,1.639789313,1.098688342,2.467232824,0.040765095,DB0113610046735_,3.199929073,0.494567766,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,carvedilol,DB01136
,129770,DB00204,10013573,52,912,38,1005,0.06630262,1.507642437,0.963267979,2.378366446,0.154719849,DB0020410013573_,1.866139226,0.410547131,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,dofetilide,DB00204
,129782,DB00215,10013911,54,11049,15,5261,0.070284527,1.714095294,0.952246212,3.273749814,0.161778431,DB0021510013911_,1.821527593,0.538885416,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,129785,DB00761,10013911,81,15226,40,8585,0.569116088,1.141787213,0.771740377,1.713573133,0.720126441,DB0076110013911_,0.328328469,0.132594765,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,129787,DB08910,10013911,53,16691,35,17453,0.041908607,1.583385669,1.013477685,2.501645312,0.109519187,DB0891010013911_,2.211655519,0.459565383,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,129791,DB00571,10028810,61,5062,27,2582,0.572864751,1.152359278,0.719357255,1.890782678,0.722835608,DB0057110028810_,0.324573457,0.141811387,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,propranolol,DB00571
,129792,DB00787,10028810,339,16661,235,17013,5.2205610430488e-06,1.473005181,1.241752898,1.749642437,6.14520586728785e-05,DB0078710028810_,9.697253221,0.387304655,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,acyclovir,DB00787
,129794,DB01234,10028810,507,31118,306,32582,1.73549276910636e-14,1.734784364,1.500972021,2.007604409,9.87390204241573e-13,DB0123410028810_,27.64371109,0.55088312,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,129795,DB08910,10028810,426,16318,302,17186,1.75795891454781e-07,1.485602265,1.276911379,1.730128295,3.02210268599667e-06,DB0891010028810_,12.70955772,0.395820256,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,129799,DB00121,10016173,155,4068,19,449,0.69824033,0.900462842,0.550835016,1.551563149,0.818519214,DB0012110016173_,0.200258408,-0.104846379,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,biotin,DB00121
,129810,DB00177,10041349,56,4744,21,2829,0.075581594,1.590128463,0.945357758,2.771063091,0.170756129,DB0017710041349_,1.767518885,0.463814807,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,valsartan,DB00177
,129811,DB09140,10041349,66,3675,26,1772,0.432713865,1.223916583,0.763644509,2.015413284,0.601108999,DB0914010041349_,0.508978997,0.202056031,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,oxygen,DB09140
,129812,DB09270,10041349,40,3074,19,2349,0.112055639,1.60860293,0.907385736,2.948852149,0.229168058,DB0927010041349_,1.473299665,0.475366057,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ubidecarenone,DB09270
,129837,DB00814,10044565,91,8196,35,3380,0.768389605,1.072223331,0.717052098,1.635516835,0.873007498,DB0081410044565_,0.135811134,0.069734372,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,129845,DB00404,10025082,50,19842,12,9850,0.02125529,2.06837939,1.085453007,4.269192996,0.064889118,DB0040410025082_,2.735075345,0.726765397,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,129846,DB00497,10025082,31,19236,21,16354,0.487024505,1.255013594,0.698146765,2.298884519,0.6509096,DB0049710025082_,0.429384509,0.227146404,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,129853,DB09140,10025082,65,3676,22,1776,0.166649137,1.427355094,0.865057055,2.439869164,0.30630905,DB0914010025082_,1.183160718,0.355823147,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,129855,DB00497,10036790,49,19218,30,16345,0.175222553,1.389142429,0.863901848,2.267782473,0.31773787,DB0049710036790_,1.146528543,0.328686599,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,129857,DB00863,10036790,62,10611,31,5809,0.744713563,1.094905385,0.699617141,1.74586919,0.854225564,DB0086310036790_,0.157559994,0.090667954,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,129863,DB14500,10053762,154,7655,61,4012,0.069831213,1.323127193,0.974898778,1.814929536,0.160981709,DB1450010053762_,1.826464529,0.27999802,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium,DB14500
,129866,DB01065,10017885,39,4292,12,3039,0.009804972,2.30094891,1.177958348,4.834890117,0.035021563,DB0106510017885_,3.351791315,0.833321607,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,melatonin,DB01065
,129868,DB00285,10060800,92,10859,23,3695,0.19807307,1.361034216,0.852849076,2.256419666,0.346720208,DB0028510060800_,1.059237141,0.308244864,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,venlafaxine,DB00285
,129871,DB00046,10000059,35,5424,30,4662,1,1.002765255,0.597030768,1.693758554,1,DB0004610000059_,0,0.002761438,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,insulin lispro,DB00046
,129872,DB01039,10000059,34,2939,39,3012,0.640004748,0.893465895,0.545456591,1.457054855,0.777057823,DB0103910000059_,0.252240513,-0.112647116,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,fenofibrate,DB01039
,129886,DB00273,10020937,141,8340,22,2171,0.024355446,1.668264909,1.056609932,2.753924337,0.072076434,DB0027310020937_,2.630028136,0.51178411,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,129887,DB00564,10020937,42,2562,9,1454,0.005078324,2.647912448,1.265872376,6.204943718,0.020711208,DB0056410020937_,3.877080276,0.973771574,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,carbamazepine,DB00564
,129889,DB00472,10027599,108,10651,6,4306,4.26791110059473e-10,7.276635409,3.233084262,20.27818928,1.26473554993385e-08,DB0047210027599_,18.1858177,1.984668586,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,129899,DB00482,10010305,63,8196,32,3039,0.163775278,0.730015811,0.468749492,1.157233215,0.302443754,DB0048210010305_,1.195859955,-0.314689086,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,celecoxib,DB00482
,129908,DB00650,10013950,21,2110,31,1983,0.124835613,0.636719465,0.346483585,1.148440794,0.248348465,DB0065010013950_,1.392922419,-0.45142612,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,leucovorin,DB00650
,129925,DB00544,10038695,27,2408,40,2613,0.22083017,0.732510947,0.430828216,1.227788891,0.374509389,DB0054410038695_,0.982138405,-0.311276993,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluorouracil,DB00544
,129926,DB00650,10038695,20,2111,49,1965,0.000216446,0.380018037,0.213143487,0.653963653,0.001539515,DB0065010038695_,6.476287639,-0.967536562,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,leucovorin,DB00650
,129945,DB00972,10013709,89,2415,48,1131,0.455674086,0.868391338,0.599994994,1.269971438,0.623043765,DB0097210013709_,0.473138513,-0.141112816,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,azelastine,DB00972
,129965,DB00958,10037087,78,4516,22,2563,0.003132589,2.012002851,1.236667292,3.401123875,0.014015335,DB0095810037087_,4.267603182,0.699130669,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,carboplatin,DB00958
,129967,DB00115,10001497,47,18378,34,10438,0.298265859,0.785145664,0.494022446,1.259684959,0.464202624,DB0011510001497_,0.767434133,-0.241886019,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,129969,DB00126,10001497,31,10140,25,5920,0.266825292,0.723981516,0.413244275,1.28016496,0.429039138,DB0012610001497_,0.846207133,-0.322989418,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,ascorbic acid,DB00126
,129979,DB00115,10061422,24,18401,31,10441,0.002851038,0.439296991,0.246572126,0.77379575,0.012973174,DB0011510061422_,4.344871604,-0.822579578,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,129987,DB00051,10024774,52,25679,32,11388,0.155460372,0.720642433,0.454987335,1.157580923,0.291450082,DB0005110024774_,1.232886534,-0.327612197,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,adalimumab,DB00051
,130002,DB00863,10040979,34,10639,24,5816,0.338417802,0.774477597,0.445469814,1.366492268,0.507487124,DB0086310040979_,0.678283941,-0.255566546,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,130009,DB00404,10066169,20,19872,30,9832,0.000117444,0.329857634,0.17743828,0.600708403,0.000915623,DB0040410066169_,6.995905352,-1.109094129,male,10066169,Substance abuse,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,130041,DB01050,10056819,68,18040,25,9346,0.154908091,1.409136336,0.878568344,2.328221045,0.290667301,DB0105010056819_,1.235575961,0.342976989,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,130050,DB00005,10066994,49,128033,24,42395,0.135135719,0.676050023,0.406846051,1.152189687,0.262861125,DB0000510066994_,1.336129429,-0.391488207,NA,10066994,Joint fluid drainage,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,130051,DB00381,10060800,119,29241,72,22815,0.093037244,1.289556154,0.9538681,1.75373229,0.200154196,DB0038110060800_,1.608667231,0.254298093,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,130052,DB00421,10060800,46,8857,8,5244,0.000559681,3.404183387,1.589390008,8.358562128,0.003388119,DB0042110060800_,5.687480247,1.225005083,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,spironolactone,DB00421
,130053,DB01222,10060800,42,9232,9,5396,0.003496029,2.727446336,1.307401693,6.377611634,0.015311691,DB0122210060800_,4.17913862,1.003365763,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,budesonide,DB01222
,130057,DB14513,10003658,92,7085,51,3513,0.532099123,0.894463411,0.626896812,1.288575143,0.688976623,DB1451310003658_,0.372547938,-0.111531282,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,magnesium,DB14513
,130058,DB00177,10047895,103,4697,65,2785,0.687600716,0.939576893,0.679624767,1.30697215,0.811687484,DB0017710047895_,0.208639884,-0.062325619,NA,10047895,Weight decreased,10022891,Investigations,Inv,valsartan,DB00177
,130060,DB00471,10030095,84,14105,24,5441,0.235732197,1.350071781,0.848111104,2.225452707,0.39287454,DB0047110030095_,0.934264955,0.300157762,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,130061,DB00482,10030095,40,8219,16,3055,0.765236946,0.929249586,0.508015725,1.780195383,0.870483106,DB0048210030095_,0.138706927,-0.073377916,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,130064,DB00295,10022004,53,14610,14,9588,0.001582635,2.484329322,1.357926486,4.851433654,0.008024607,DB0029510022004_,4.825242527,0.910002733,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,130072,DB00028,10017577,40,13418,27,5588,0.059558918,0.616988222,0.368950534,1.046602657,0.142649429,DB0002810017577_,1.947365204,-0.482905344,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,130075,DB00776,10017577,50,1855,21,1318,0.050601096,1.691432325,0.99198123,2.980027633,0.126102553,DB0077610017577_,2.070659793,0.5255757,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,oxcarbazepine,DB00776
,130096,DB00331,10039203,57,24889,31,20721,0.067894571,1.530775372,0.97137391,2.453958934,0.157532666,DB0033110039203_,1.848122438,0.425774386,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,130100,DB00402,10013700,49,1303,10,686,0.004868091,2.578739406,1.280284881,5.746534944,0.020029393,DB0040210013700_,3.910554415,0.947300677,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,eszopiclone,DB00402
,130138,DB01225,10010305,53,4991,58,4582,0.390167494,0.838926824,0.565656992,1.241898867,0.560038577,DB0122510010305_,0.57974961,-0.175631794,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,enoxaparin,DB01225
,130152,DB00230,10013710,115,19559,47,8604,0.732427803,1.076346769,0.759554186,1.546715666,0.844528198,DB0023010013710_,0.168977154,0.073572685,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,130155,DB06655,10013700,49,3639,18,2101,0.124898128,1.571577911,0.896532056,2.874387553,0.248435226,DB0665510013700_,1.392573126,0.452080153,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,liraglutide,DB06655
,130157,DB01234,10018985,21,31604,31,32857,0.266815452,0.704283344,0.384553775,1.265797871,0.429036439,DB0123410018985_,0.846213424,-0.350574526,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,130165,DB08904,10037087,219,11391,59,3500,0.392260959,1.140496663,0.849652237,1.551382999,0.562144824,DB0890410037087_,0.575995768,0.131463836,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,certolizumab pegol,DB08904
,130173,DB00051,10016766,42,25689,18,11402,1,1.035613603,0.583109217,1.912266912,1,DB0005110016766_,0,0.034994104,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,130174,DB00635,10016766,73,32980,50,23744,0.854926415,1.051135616,0.723251954,1.538491666,0.929630334,DB0063510016766_,0.072968262,0.049871119,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,130175,DB00736,10016766,60,10531,40,5513,0.246150176,0.785284845,0.516949658,1.204244745,0.40508749,DB0073610016766_,0.903652211,-0.241708767,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,130193,DB00051,10041101,58,25673,60,11360,5.26058117852783e-06,0.427745043,0.29273321,0.624653499,6.18538923183199e-05,DB0005110041101_,9.69073553,-0.849227956,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,130197,DB01225,10042674,32,5012,22,4618,0.339465235,1.340158413,0.753641972,2.42458803,0.508569034,DB0122510042674_,0.676154313,0.292787825,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,130239,DB06724,10013786,63,7866,13,3906,0.002157499,2.406293095,1.308855773,4.772446444,0.010355129,DB0672410013786_,4.570273287,0.878087429,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,calcium carbonate,DB06724
,130240,DB00136,10020583,42,2050,15,1667,0.00672119,2.276371276,1.231618762,4.435437562,0.025936502,DB0013610020583_,3.652103974,0.822582629,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,calcitriol,DB00136
,130247,DB00410,10047895,42,1563,34,975,0.282699224,0.770668628,0.474975529,1.258419098,0.446814534,DB0041010047895_,0.805611682,-0.260496793,NA,10047895,Weight decreased,10022891,Investigations,Inv,mupirocin,DB00410
,130249,DB00581,10061428,49,2064,57,2012,0.37774019,0.838027958,0.557200625,1.256366178,0.547720732,DB0058110061428_,0.601989736,-0.176703816,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,lactulose,DB00581
,130250,DB01109,10061428,66,4346,36,4234,0.005128733,1.785960641,1.169624845,2.766684837,0.020877924,DB0110910061428_,3.869062961,0.579956445,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,heparin,DB01109
,130265,DB01202,10015150,43,6671,14,5704,0.001202101,2.625922783,1.407420993,5.20221896,0.006413467,DB0120210015150_,5.049355319,0.965432371,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,levetiracetam,DB01202
,130301,DB00502,10044565,26,1368,49,1823,0.193576916,0.707168725,0.41959376,1.167119471,0.341144434,DB0050210044565_,1.075449331,-0.346485992,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,haloperidol,DB00502
,130305,DB00678,10029354,66,15533,64,10660,0.04944717,0.707750249,0.493663967,1.015171198,0.123977571,DB0067810029354_,2.08765461,-0.345664004,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,losartan,DB00678
,130316,DB01015,10013950,86,9801,53,9328,0.013378062,1.544290929,1.082773521,2.220267069,0.044901023,DB0101510013950_,3.103294704,0.434564859,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,130328,DB00087,10037844,81,1288,32,715,0.128862377,1.404943128,0.912006393,2.209906137,0.253962008,DB0008710037844_,1.370570599,0.339996823,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,alemtuzumab,DB00087
,130355,DB00741,10030124,47,4047,29,3145,0.354053886,1.259428275,0.774361426,2.080269736,0.52391524,DB0074110030124_,0.646425364,0.230657868,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,130366,DB00571,10033295,86,5037,41,2568,0.776944803,1.069389364,0.726554709,1.596539194,0.878478692,DB0057110033295_,0.129563626,0.067087798,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,propranolol,DB00571
,130372,DB01234,10005734,76,31549,85,32803,0.693274844,0.929628673,0.672873273,1.282486089,0.815261689,DB0123410005734_,0.204246127,-0.072970049,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,130376,DB01234,10045555,52,31573,53,32835,0.922555093,1.020351849,0.682170384,1.525488366,0.965994527,DB0123410045555_,0.03459711,0.020147518,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,130379,DB00669,10002855,136,6241,18,1079,0.356566159,1.306228258,0.791960505,2.280046285,0.526242168,DB0066910002855_,0.641993776,0.267143792,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,sumatriptan,DB00669
,130382,DB01591,10012378,43,1912,10,646,0.339180915,1.452594959,0.713604249,3.261124622,0.508287933,DB0159110012378_,0.676707195,0.373351584,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,solifenacin,DB01591
,130383,DB00268,10022437,98,2877,39,1506,0.170115865,1.315301312,0.893685919,1.969085312,0.311006469,DB0026810022437_,1.167941566,0.274065774,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ropinirole,DB00268
,130384,DB00669,10022437,102,6275,21,1076,0.440851232,0.832909499,0.514293482,1.409555336,0.609127528,DB0066910022437_,0.495727628,-0.182830287,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,sumatriptan,DB00669
,130385,DB01591,10022437,41,1914,10,646,0.417721773,1.383616971,0.676730387,3.115710744,0.586748079,DB0159110022437_,0.533159718,0.324701064,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,solifenacin,DB01591
,130388,DB06655,10046571,59,3629,11,2108,0.000151289,3.11510773,1.616272515,6.590787087,0.001135813,DB0665510046571_,6.780406149,1.136263736,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,liraglutide,DB06655
,130390,DB01067,10047899,73,4288,44,4779,0.001436036,1.84892539,1.251772154,2.758865436,0.007418672,DB0106710047899_,4.903755244,0.6146046,NA,10047899,Weight increased,10022891,Investigations,Inv,glipizide,DB01067
,130453,DB00136,10019211,72,2020,41,1641,0.083391147,1.426478157,0.953187393,2.159781693,0.184103502,DB0013610019211_,1.69225717,0.355208579,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,calcitriol,DB00136
,130457,DB00136,10033425,44,2048,18,1664,0.014049837,1.985743194,1.119218227,3.665846488,0.046726129,DB0013610033425_,3.063451771,0.685993249,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,calcitriol,DB00136
,130466,DB00956,10048959,108,5706,47,3420,0.078364971,1.377228001,0.966424624,1.988842734,0.175647929,DB0095610048959_,1.739273693,0.320072784,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,130468,DB08877,10055798,33,3256,41,3188,0.350006787,0.78809938,0.481433046,1.281161255,0.519607982,DB0887710055798_,0.654680632,-0.23813108,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,ruxolitinib,DB08877
,130497,DB00563,10039203,73,46573,18,15330,0.330562032,1.334908193,0.788312276,2.377527344,0.499271563,DB0056310039203_,0.694605117,0.28886252,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,130503,DB01076,10019708,34,25713,19,25564,0.053380475,1.779073952,0.98610313,3.302650111,0.131349406,DB0107610019708_,2.029894282,0.576092977,NA,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,atorvastatin,DB01076
,130509,DB00321,10013950,49,7398,7,2843,0.010187889,2.689661971,1.210056408,7.047852336,0.036099754,DB0032110013950_,3.321469228,0.989415524,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,amitriptyline,DB00321
,130515,DB00316,10029202,69,65405,39,36914,1,0.99853806,0.664649559,1.519383671,1,DB0031610029202_,0,-0.001463009,NA,10029202,Nervous system disorder,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,130538,DB05676,10021425,44,47085,16,25313,0.22246018,1.478398373,0.817690343,2.807385105,0.376545799,DB0567610021425_,0.976715596,0.390959322,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,apremilast,DB05676
,130539,DB05676,10028391,101,47028,38,25291,0.06167673,1.429371774,0.975035617,2.134730707,0.146513587,DB0567610028391_,1.920637108,0.357235029,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,130545,DB00230,10015535,50,19624,17,8634,0.426001303,1.293987313,0.733144946,2.394769346,0.594755567,DB0023010015535_,0.519604769,0.257728391,NA,10015535,Euphoric mood,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,130559,DB00273,10039897,39,8442,29,2164,3.14469065432994e-05,0.344775132,0.207243912,0.579533161,0.00029563,DB0027310039897_,8.126401331,-1.064862865,male,10039897,Sedation,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,130569,DB01175,10001497,75,10649,67,4825,8.06515266164892e-05,0.507200429,0.359266026,0.717342933,0.000664033,DB0117510001497_,7.317178699,-0.678849031,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,130579,DB00734,10033864,39,4011,39,4863,0.424808184,1.212385487,0.75597458,1.944259628,0.593593276,DB0073410033864_,0.521560914,0.192589896,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,130582,DB00734,10042464,30,4020,38,4864,0.903014964,0.955220182,0.570411293,1.586439499,0.957326661,DB0073410042464_,0.043610607,-0.045813408,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,130584,DB00734,10043071,31,4019,79,4823,0.000320664,0.470952788,0.299685642,0.723582444,0.002130597,DB0073410043071_,6.151352935,-0.752997427,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,risperidone,DB00734
,130585,DB01175,10043071,49,10675,29,4863,0.271774793,0.769708711,0.476032438,1.265362892,0.434631323,DB0117510043071_,0.83325714,-0.261743133,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,escitalopram,DB01175
,130594,DB00186,10066901,33,16868,19,9989,1,1.028534529,0.567632516,1.915671543,1,DB0018610066901_,0,0.028135002,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,130600,DB01068,10066901,40,13723,16,6824,0.569990016,1.243121126,0.680228827,2.379689784,0.720782622,DB0106810066901_,0.327417683,0.217625254,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,130607,DB00331,10017888,41,24905,23,20729,0.133506461,1.483690163,0.86929488,2.591108884,0.260636467,DB0033110017888_,1.344628688,0.394532338,NA,10017888,Gastroenteritis,10021881,Infections and infestations,Infec,metformin,DB00331
,130609,DB00175,10019303,38,8093,17,6089,0.076835676,1.681722873,0.92549677,3.180760576,0.172913163,DB0017510019303_,1.754965757,0.519818787,NA,10019303,Heart rate increased,10022891,Investigations,Inv,pravastatin,DB00175
,130621,DB08934,10048959,39,4450,31,6173,0.02106121,1.745042543,1.059241725,2.897511047,0.064412579,DB0893410048959_,2.742446333,0.556778935,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,130634,DB00877,10012735,68,1040,62,1369,0.045644599,1.443500398,0.997969003,2.091174115,0.116805559,DB0087710012735_,2.14724462,0.367070996,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sirolimus,DB00877
,130635,DB00877,10013968,29,1079,43,1388,0.630151096,0.86761378,0.51867049,1.432617882,0.769126399,DB0087710013968_,0.262499955,-0.142008618,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sirolimus,DB00877
,130646,DB00877,10037660,48,1060,71,1360,0.507792475,0.867447341,0.58314959,1.280918794,0.668469234,DB0087710037660_,0.402764906,-0.142200471,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sirolimus,DB00877
,130652,DB00104,10051398,37,1444,19,1058,0.221372193,1.42661838,0.794495127,2.641999706,0.375210736,DB0010410051398_,0.980267449,0.355306874,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,octreotide,DB00104
,130679,DB00688,10003988,50,6440,26,5352,0.06370595,1.598119478,0.974492539,2.678571033,0.150139953,DB0068810003988_,1.896187399,0.468827612,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,mycophenolate mofetil,DB00688
,130680,DB00864,10021143,48,6821,75,8317,0.202720813,0.780379845,0.530776566,1.137734575,0.352183599,DB0086410021143_,1.043602651,-0.247974496,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tacrolimus,DB00864
,130681,DB01222,10021143,93,9181,70,5335,0.120470039,0.772051455,0.559017862,1.070389044,0.242039452,DB0122210021143_,1.418654543,-0.25870408,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,130682,DB00688,10035598,40,6450,40,5338,0.430969465,0.827612836,0.519564241,1.318330152,0.599393743,DB0068810035598_,0.511836562,-0.189209824,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolate mofetil,DB00688
,130683,DB01222,10035598,59,9215,44,5361,0.219611902,0.780127641,0.518273618,1.182028546,0.372972724,DB0122210035598_,0.986249989,-0.248297731,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,130684,DB00688,10038687,31,6459,24,5354,0.892234448,1.070703451,0.60738754,1.908957331,0.955096007,DB0068810038687_,0.045943412,0.068315863,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolate mofetil,DB00688
,130685,DB00864,10038687,54,6815,44,8348,0.052483328,1.503282496,0.989562376,2.294849028,0.129666724,DB0086410038687_,2.042787781,0.407651048,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tacrolimus,DB00864
,130706,DB00864,10011831,118,6751,139,8253,0.800423895,1.037807675,0.803252626,1.338952245,0.892093881,DB0086410011831_,0.114183904,0.037110484,NA,10011831,Cytomegalovirus infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,130712,DB06655,10035664,42,3646,28,2091,0.534778945,0.860286207,0.519095105,1.445790847,0.691356707,DB0665510035664_,0.36909937,-0.150490146,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,liraglutide,DB06655
,130722,DB00635,10001949,69,32984,46,23748,0.706242778,1.079993405,0.732754117,1.604855836,0.824077927,DB0063510001949_,0.193490181,0.076954935,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,130724,DB00635,10044390,62,32991,44,23750,1,1.0143955,0.67802753,1.529054799,1,DB0063510044390_,0,0.014292868,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,130727,DB00410,10013700,44,1561,20,989,0.243721916,1.393679699,0.79881423,2.511606311,0.402116208,DB0041010013700_,0.911014158,0.331947515,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,mupirocin,DB00410
,130728,DB00646,10013700,75,3378,21,1979,0.002577354,2.092066094,1.27063232,3.58587639,0.011948312,DB0064610013700_,4.427165296,0.738152139,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,nystatin,DB00646
,130730,DB00410,10037844,80,1525,30,979,0.01233916,1.711581113,1.102620907,2.71960183,0.042087634,DB0041010037844_,3.1680013,0.537417571,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,mupirocin,DB00410
,130731,DB00514,10037844,44,2122,21,1515,0.161921719,1.495735862,0.86642087,2.65997115,0.299979728,DB0051410037844_,1.204040379,0.402618301,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dextromethorphan,DB00514
,130733,DB01307,10037844,54,2470,35,2034,0.284105432,1.27044812,0.811598099,2.011649247,0.448627635,DB0130710037844_,0.801562056,0.239369688,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,insulin detemir,DB01307
,130763,DB14500,10040047,96,7713,81,3992,0.001774108,0.613419868,0.450473437,0.83714274,0.008811873,DB1450010040047_,4.73165526,-0.488705638,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,potassium,DB14500
,130790,DB00126,10043071,48,10123,31,5914,0.726035525,0.904597393,0.563409589,1.47190773,0.839588375,DB0012610043071_,0.174843537,-0.100265303,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,ascorbic acid,DB00126
,130791,DB00158,10043071,73,16742,34,8070,0.917915459,1.034902279,0.67933732,1.605302326,0.963555238,DB0015810043071_,0.037125462,0.034307006,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,folic acid,DB00158
,130794,DB01118,10043071,19,3044,35,4674,0.577968005,0.83358636,0.449547364,1.500862977,0.726797704,DB0111810043071_,0.319107101,-0.182017971,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,amiodarone,DB01118
,130849,DB00318,10020751,61,4222,13,1826,0.020888807,2.029206654,1.099558499,4.036567123,0.063959728,DB0031810020751_,2.749501641,0.707644906,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,codeine,DB00318
,130856,DB00316,10038669,447,65027,297,36656,0.029021725,0.848412139,0.730559014,0.986387685,0.082531216,DB0031610038669_,2.494578682,-0.164388749,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,130880,DB00588,10014011,92,16432,37,8431,0.226230221,1.27581069,0.86141649,1.924325039,0.381134557,DB0058810014011_,0.964602797,0.243581812,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,130882,DB00005,10065433,49,128033,19,42400,0.574917412,0.854083035,0.49366418,1.5363665,0.724521356,DB0000510065433_,0.322244041,-0.157726859,NA,10065433,Ligament rupture,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,130897,DB00321,10043607,38,7409,19,2831,0.372782278,0.764220021,0.428930254,1.405934888,0.542497075,DB0032110043607_,0.611572585,-0.268899545,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,amitriptyline,DB00321
,130899,DB01233,10048959,45,3376,13,1713,0.092168312,1.756229649,0.927944504,3.558679816,0.198691386,DB0123310048959_,1.616002481,0.563169266,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,130907,DB00904,10036590,32,23037,29,14427,0.149820958,0.691065152,0.404688091,1.184527676,0.283686525,DB0090410036590_,1.259885437,-0.369521173,NA,10036590,Premature baby,10036585,"Pregnancy, puerperium and perinatal conditions",Preg,ondansetron,DB00904
,130913,DB00904,10071404,115,22954,141,14315,9.64681855818164e-08,0.508639763,0.393729545,0.65595978,1.74873535035727e-06,DB0090410071404_,13.25661769,-0.676015248,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,130961,DB00203,10043071,118,13760,40,8898,0.000295317,1.907583691,1.320990875,2.806193424,0.001992403,DB0020310043071_,6.218413824,0.645837358,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,sildenafil,DB00203
,130962,DB01240,10043071,98,5653,23,1553,0.577163956,1.170526142,0.73436114,1.939108804,0.726267905,DB0124010043071_,0.319836317,0.157453342,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,epoprostenol,DB01240
,130976,DB01592,10007882,40,6236,21,3046,0.785538394,0.930397528,0.534582509,1.664008317,0.88367186,DB0159210007882_,0.123669484,-0.072143335,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,iron,DB01592
,130983,DB06724,10010305,87,7842,50,3869,0.41133413,0.85848249,0.598071981,1.243978522,0.580708307,DB0672410010305_,0.543506702,-0.152588995,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,calcium carbonate,DB06724
,131013,DB14500,10061024,72,7737,58,4015,0.015419148,0.644199168,0.44854703,0.928740183,0.050378161,DB1450010061024_,2.988197512,-0.439747333,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,potassium,DB14500
,131014,DB00222,10062237,25,3181,30,3098,0.499024699,0.811618041,0.456584885,1.431258921,0.66093239,DB0022210062237_,0.414103729,-0.208725443,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,glimepiride,DB00222
,131016,DB00331,10062237,106,24840,109,20643,0.130824771,0.808173094,0.612260244,1.066462938,0.256947554,DB0033110062237_,1.358883284,-0.212979019,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,131018,DB14500,10062237,43,7766,24,4049,0.797084959,0.934137046,0.553381311,1.611808891,0.890165409,DB1450010062237_,0.11634798,-0.068132121,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,potassium,DB14500
,131033,DB00264,10003119,79,29528,91,24801,0.044734853,0.729166728,0.532234942,0.997127886,0.115065625,DB0026410003119_,2.16225266,-0.315852866,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,metoprolol,DB00264
,131041,DB00904,10003119,36,23033,35,14421,0.067363339,0.644020291,0.392827011,1.056753355,0.1566182,DB0090410003119_,1.853944281,-0.440025046,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,ondansetron,DB00904
,131043,DB00996,10003119,41,38912,36,22389,0.075040085,0.655321884,0.408390932,1.055625014,0.169897811,DB0099610003119_,1.772558132,-0.422628738,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,gabapentin,DB00996
,131072,DB00364,10008479,58,2692,30,1370,1,0.983898851,0.619422476,1.591934224,1,DB0036410008479_,0,-0.016232181,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,sucralfate,DB00364
,131074,DB01225,10008479,65,4979,65,4575,0.659092564,0.918876188,0.639782317,1.319661966,0.791749239,DB0122510008479_,0.233510554,-0.084603891,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,131102,DB01076,10018838,59,25688,46,25537,0.241202331,1.275060135,0.852144967,1.918261001,0.399358334,DB0107610018838_,0.917896185,0.242993343,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,131104,DB00181,10018884,46,9810,40,5831,0.092987029,0.683593864,0.437082469,1.073089861,0.20007073,DB0018110018884_,1.609084326,-0.380391304,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,baclofen,DB00181
,131106,DB00364,10018884,50,2700,24,1376,0.901450926,1.061717074,0.637185975,1.814458532,0.95698137,DB0036410018884_,0.043971355,0.059887478,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,sucralfate,DB00364
,131107,DB00537,10018884,57,7500,44,4254,0.145187117,0.734824011,0.486210628,1.117004517,0.277313037,DB0053710018884_,1.282608312,-0.308124249,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ciprofloxacin,DB00537
,131109,DB00582,10021097,30,1100,44,1530,0.905038233,0.948357566,0.571740846,1.5539061,0.957667115,DB0058210021097_,0.043255041,-0.053023669,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,voriconazole,DB00582
,131113,DB00295,10028116,38,14625,15,9587,0.121022971,1.660619318,0.891825963,3.251541134,0.242914649,DB0029510028116_,1.415045134,0.507190616,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,131127,DB00582,10028813,49,1081,45,1529,0.043051975,1.539871502,0.998190556,2.380597396,0.111776092,DB0058210028813_,2.191257583,0.431698973,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,voriconazole,DB00582
,131129,DB01060,10035528,45,8542,65,5016,3.65275115680868e-06,0.406559746,0.271198778,0.604786353,4.48971541532459e-05,DB0106010035528_,10.01113615,-0.900024384,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,amoxicillin,DB01060
,131133,DB01060,10035598,32,8555,39,5042,0.002854584,0.483597555,0.292895338,0.793284084,0.012985937,DB0106010035598_,4.343888302,-0.726502217,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amoxicillin,DB01060
,131140,DB09153,10037377,41,7758,38,5661,0.305001302,0.787326827,0.493205935,1.259665436,0.471780098,DB0915310037377_,0.751242295,-0.239111835,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,131141,DB00601,10037660,29,876,42,869,0.145953502,0.685104045,0.407531945,1.137706182,0.278382397,DB0060110037660_,1.278759582,-0.378184562,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,linezolid,DB00601
,131158,DB00181,10040070,43,9813,24,5847,0.899420673,1.067553271,0.632712574,1.841180623,0.956490275,DB0018110040070_,0.044484657,0.065369367,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,baclofen,DB00181
,131159,DB00295,10040070,48,14615,42,9560,0.19473495,0.747590736,0.483294647,1.160272652,0.3426798,DB0029510040070_,1.070958795,-0.290899595,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,morphine,DB00295
,131160,DB00319,10040070,58,1334,49,1804,0.017214891,1.600440227,1.067644488,2.407463057,0.054934249,DB0031910040070_,2.901618282,0.470278733,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,piperacillin,DB00319
,131161,DB00582,10040070,18,1112,49,1525,0.012027436,0.503902416,0.274693115,0.886257235,0.041223256,DB0058210040070_,3.188752712,-0.685372649,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,voriconazole,DB00582
,131163,DB00927,10040070,41,7456,34,4982,0.347756319,0.805776096,0.498142578,1.311035398,0.517319384,DB0092710040070_,0.659094832,-0.215949371,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,famotidine,DB00927
,131165,DB01076,10040070,84,25663,85,25498,0.938651337,0.981879292,0.717159483,1.344076531,0.978327864,DB0107610040070_,0.021910426,-0.018286899,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,131166,DB01225,10040070,45,4999,37,4603,0.657721565,1.119851582,0.707297809,1.78289295,0.790788187,DB0122510040070_,0.234725126,0.11319616,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,enoxaparin,DB01225
,131170,DB00537,10043071,37,7520,29,4269,0.200596635,0.724333379,0.432789188,1.222979814,0.349747871,DB0053710043071_,1.050542752,-0.322503524,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,ciprofloxacin,DB00537
,131172,DB00758,10043071,21,8279,31,10043,0.57723443,0.821765805,0.448436824,1.477851092,0.726326958,DB0075810043071_,0.31975501,-0.196299834,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,131173,DB01225,10043071,58,4986,67,4573,0.208051365,0.793987949,0.547510893,1.148464565,0.358857545,DB0122510043071_,1.024829778,-0.230686996,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,enoxaparin,DB01225
,131174,DB09153,10043071,48,7751,67,5632,0.000591376,0.520597336,0.351086986,0.766828706,0.003552581,DB0915310043071_,5.640080978,-0.652778403,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,sodium chloride,DB09153
,131183,DB00904,10044640,36,23033,30,14426,0.256250767,0.751603035,0.449864143,1.263993257,0.417062007,DB0090410044640_,0.87452037,-0.285546973,NA,10044640,Tricuspid valve incompetence,10007541,Cardiac disorders,Card,ondansetron,DB00904
,131209,DB00364,10047700,145,2605,63,1337,0.293076608,1.181258797,0.866052718,1.626348227,0.458679288,DB0036410047700_,0.779404033,0.166580647,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sucralfate,DB00364
,131216,DB00927,10047943,36,7461,20,4996,0.585258355,1.205265836,0.678391664,2.200184591,0.732792639,DB0092710047943_,0.310892511,0.186700154,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,famotidine,DB00927
,131218,DB01076,10047943,81,25666,59,25524,0.075361318,1.365272459,0.963722225,1.944062716,0.170434264,DB0107610047943_,1.769405604,0.311354013,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,atorvastatin,DB01076
,131268,DB01076,10056342,37,25710,30,25553,0.463678242,1.225794969,0.736655937,2.055149258,0.63090292,DB0107610056342_,0.46060328,0.203589588,NA,10056342,Pulmonary mass,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,131375,DB00564,10010305,40,2564,26,1437,0.605374774,0.862272375,0.511002857,1.478237199,0.74851358,DB0056410010305_,0.289665932,-0.148184078,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,carbamazepine,DB00564
,131440,DB00425,10041347,25,12670,40,7444,8.30825239814003e-05,0.367224064,0.213319396,0.62091759,0.000681062,DB0042510041347_,7.291857745,-1.00178309,male,10041347,Somnambulism,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,131445,DB00996,10049816,64,38889,26,22399,0.154179031,1.41777092,0.885633721,2.331309585,0.289760892,DB0099610049816_,1.238699208,0.349085864,NA,10049816,Muscle tightness,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,131470,DB00188,10023547,108,7778,86,8742,0.020404992,1.411419202,1.051554344,1.899262879,0.062781833,DB0018810023547_,2.768089526,0.344595724,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,bortezomib,DB00188
,131471,DB00374,10037087,201,17515,49,5675,0.075920213,1.329063561,0.966799778,1.858165157,0.171359134,DB0037410037087_,1.763993724,0.284474605,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,treprostinil,DB00374
,131472,DB00559,10037087,76,9583,21,3285,0.415345188,1.240561314,0.755523244,2.12160974,0.58456566,DB0055910037087_,0.53688617,0.21556395,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,bosentan,DB00559
,131476,DB00904,10042674,172,22897,65,14391,0.000370473,1.663112006,1.242254885,2.249720417,0.002405011,DB0090410042674_,6.030200938,0.50869055,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,131491,DB00273,10017885,44,8437,10,2183,0.866004952,1.138447524,0.563358812,2.541112765,0.939258929,DB0027310017885_,0.062664088,0.129665513,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,topiramate,DB00273
,131493,DB01222,10027599,68,9206,18,5387,0.002258713,2.210503125,1.297871698,3.954611027,0.010742836,DB0122210027599_,4.533516154,0.793220148,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,131499,DB00273,10037153,61,8420,12,2181,0.467638641,1.316679361,0.700373918,2.691679787,0.634174213,DB0027310037153_,0.455431578,0.275112932,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,topiramate,DB00273
,131500,DB01222,10037153,69,9205,19,5386,0.002614969,2.124798194,1.262142757,3.743950775,0.012086243,DB0122210037153_,4.41568738,0.75367683,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,budesonide,DB01222
,131541,DB00656,10061024,33,11980,30,6589,0.048328266,0.604990117,0.357368742,1.027956435,0.121937914,DB0065610061024_,2.104243263,-0.502543156,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,trazodone,DB00656
,131546,DB00682,10028309,6,19453,50,16314,1.02468837345617e-11,0.100642635,0.035241737,0.234919734,3.90913409235058e-10,DB0068210028309_,21.66253504,-2.296179308,male,10028309,Muscle haemorrhage,10028395,Musculoskeletal and connective tissue disorders,Musc,warfarin,DB00682
,131552,DB00331,10009802,37,24909,40,20712,0.254280431,0.769152777,0.478151107,1.23439877,0.414882752,DB0033110009802_,0.879759324,-0.262465659,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,metformin,DB00331
,131553,DB00331,10017853,48,24898,34,20718,0.506597379,1.174745977,0.741204305,1.880635773,0.667330466,DB0033110017853_,0.404469905,0.161051935,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,131574,DB09270,10018884,36,3078,39,2329,0.128033789,0.698512008,0.430013915,1.131882741,0.252881206,DB0927010018884_,1.374835443,-0.358802909,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ubidecarenone,DB09270
,131575,DB14513,10018884,79,7098,42,3522,0.699145064,0.933328526,0.632549121,1.394480256,0.819086647,DB1451310018884_,0.199565405,-0.068998022,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,magnesium,DB14513
,131579,DB09270,10028372,46,3068,25,2343,0.185951774,1.405102626,0.842631698,2.394031236,0.331394831,DB0927010028372_,1.10444477,0.340110344,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,ubidecarenone,DB09270
,131580,DB14513,10035528,94,7083,70,3494,0.011923078,0.662433577,0.479642278,0.918591668,0.040949412,DB1451310035528_,3.195417835,-0.411834987,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,magnesium,DB14513
,131582,DB14513,10047571,54,7123,20,3544,0.321465375,1.34335947,0.789616845,2.373163339,0.489768386,DB1451310047571_,0.713822682,0.295173543,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,magnesium,DB14513
,131584,DB00451,10047654,40,47231,10,15409,0.514573022,1.304973252,0.641113636,2.926848898,0.674490195,DB0045110047654_,0.39379814,0.266182544,NA,10047654,Vitreous floaters,10015919,Eye disorders,Eye,levothyroxine,DB00451
,131591,DB00158,10009900,41,16774,17,8087,0.675027065,1.162730515,0.645716591,2.184292962,0.802945891,DB0015810009900_,0.21946795,0.150771132,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,131595,DB00904,10009900,41,23028,18,14438,0.229650584,1.428098293,0.80196487,2.642070114,0.385513194,DB0090410009900_,0.953179861,0.356343694,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,131599,DB00169,10036807,34,38657,23,18152,0.20037842,0.694131832,0.396974752,1.234547351,0.349464006,DB0016910036807_,1.051354709,-0.365093377,NA,10036807,Progressive multifocal leukoencephalopathy,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,131631,DB00497,10031252,30,19237,26,16349,1,0.980618676,0.560269062,1.726859337,1,DB0049710031252_,0,-0.019571605,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,oxycodone,DB00497
,131639,DB00497,10037400,63,19204,26,16349,0.00184722,2.062762181,1.286598153,3.396008286,0.009113875,DB0049710037400_,4.697957278,0.724045949,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,131650,DB01238,10010774,58,5192,33,3469,0.519199729,1.174258288,0.751326478,1.86323363,0.678423388,DB0123810010774_,0.38798372,0.160636704,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,aripiprazole,DB01238
,131652,DB00158,10003246,152,16663,31,8073,2.40473800789221e-06,2.375477383,1.604305229,3.621477649,3.10989119495433e-05,DB0015810003246_,10.37833772,0.865198421,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,131653,DB00814,10003246,91,8196,31,3384,0.423112462,1.211982847,0.796560554,1.889388794,0.59199484,DB0081410003246_,0.52425736,0.192257735,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,131654,DB00695,10039073,141,27908,22,20506,1.92054177207625e-15,4.70907388,2.990111144,7.75592053,1.2433852334735e-13,DB0069510039073_,29.71576852,1.54949126,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,131656,DB00635,10021688,72,32981,24,23770,0.000828339,2.162109796,1.34526784,3.590568767,0.004712744,DB0063510021688_,5.35748485,0.771084502,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,131663,DB09270,10028334,83,3031,41,2327,0.021853067,1.554069172,1.052125673,2.327366545,0.066287781,DB0927010028334_,2.7137497,0.440876763,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ubidecarenone,DB09270
,131664,DB09270,10047513,41,3073,20,2348,0.118438894,1.566226705,0.894047809,2.829791802,0.238867976,DB0927010047513_,1.431844281,0.448669354,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ubidecarenone,DB09270
,131665,DB09270,10047899,75,3039,50,2318,0.522787578,1.144076691,0.78590353,1.67783422,0.68123201,DB0927010047899_,0.383852341,0.134597928,NA,10047899,Weight increased,10022891,Investigations,Inv,ubidecarenone,DB09270
,131690,DB00338,10035742,56,33618,58,22214,0.016711414,0.638015399,0.433752749,0.937789371,0.053659849,DB0033810035742_,2.925090254,-0.449392859,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,131712,DB00863,10005750,102,10571,54,5786,0.86683719,1.033876184,0.735054258,1.468247714,0.939967637,DB0086310005750_,0.061909833,0.033315024,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,ranitidine,DB00863
,131714,DB00959,10006451,106,7972,33,4969,0.000302548,2.002035721,1.340756313,3.061032367,0.002031287,DB0095910006451_,6.199085864,0.694164523,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,131717,DB09072,10011224,96,6375,25,2510,0.067280803,1.511895461,0.962586591,2.457233326,0.156480838,DB0907210011224_,1.854821718,0.413364136,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium oxybate,DB09072
,131718,DB04861,10016322,31,1934,24,1363,0.783011058,0.910337751,0.514540841,1.628794189,0.881832675,DB0486110016322_,0.125752951,-0.093939594,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,nebivolol,DB04861
,131719,DB00635,10019063,69,32984,64,23730,0.159026334,0.77565706,0.543709864,1.107942837,0.296202323,DB0063510019063_,1.216712534,-0.25404479,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,131720,DB00736,10019063,48,10543,32,5521,0.290395641,0.785529208,0.491317443,1.271272452,0.455649436,DB0073610019063_,0.786031546,-0.241397638,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,esomeprazole,DB00736
,131761,DB00661,10047899,52,3476,11,1584,0.019283936,2.153927643,1.106498323,4.590997055,0.060092265,DB0066110047899_,2.811874143,0.767292986,NA,10047899,Weight increased,10022891,Investigations,Inv,verapamil,DB00661
,131766,DB00761,10068319,103,15204,26,8599,0.000101409,2.240477734,1.4442748,3.593338502,0.000807618,DB0076110068319_,7.121421373,0.806689117,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,131781,DB00215,10013781,67,11036,16,5260,0.012835947,1.995781124,1.142662027,3.6935586,0.043452437,DB0021510013781_,3.136088342,0.691035515,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,131782,DB00381,10013781,172,29188,74,22813,1.07560293159325e-05,1.816631444,1.374735827,2.420577885,0.000115586,DB0038110013781_,9.065499697,0.596983931,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,131785,DB00852,10013700,162,1004,21,450,6.32937046676228e-09,3.455539405,2.151258921,5.813025263,1.48941363221886e-07,DB0085210013700_,15.71971314,1.239978568,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,pseudoephedrine,DB00852
,131809,DB00182,10001497,49,5145,48,2804,0.00521274,0.556362808,0.364925723,0.848685203,0.021151106,DB0018210001497_,3.856063099,-0.586334666,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,131814,DB01076,10001497,60,25687,98,25485,0.002377217,0.60743991,0.432794916,0.846531919,0.011203074,DB0107610001497_,4.491567065,-0.498502022,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,131815,DB09072,10001497,66,6405,50,2485,0.000547556,0.51215037,0.348214448,0.757432722,0.003326213,DB0907210001497_,5.705920939,-0.669137007,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,131831,DB00620,10010264,104,4724,50,3082,0.080608515,1.356968576,0.956304659,1.947468362,0.179399248,DB0062010010264_,1.718141521,0.305253223,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,131832,DB00741,10010264,63,4031,37,3137,0.187807543,1.325023641,0.866712948,2.051559986,0.333853263,DB0074110010264_,1.097053715,0.281430302,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,131840,DB00909,10013573,38,782,19,462,0.67408431,1.181395727,0.655370749,2.196963181,0.802332333,DB0090910013573_,0.220232376,0.166696559,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,zonisamide,DB00909
,131841,DB00182,10013781,51,5143,12,2840,0.005340203,2.346664564,1.231710308,4.8434208,0.021556822,DB0018210013781_,3.837062933,0.852994985,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,amphetamine,DB00182
,131843,DB00682,10013781,74,19385,27,16337,0.00012189,2.309687455,1.467693191,3.735671333,0.000945213,DB0068210013781_,6.964100166,0.837112214,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,131845,DB01076,10013781,138,25609,74,25509,1.28722887102158e-05,1.857549766,1.389830102,2.499656829,0.000135583,DB0107610013781_,8.905924395,0.619258289,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,131866,DB00909,10016256,38,782,15,466,0.194336943,1.509181943,0.800656878,2.987144229,0.342157392,DB0090910016256_,1.072484436,0.411567744,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,zonisamide,DB00909
,131867,DB00620,10016322,62,4766,17,3115,0.001060451,2.383433924,1.372758513,4.357440312,0.005784777,DB0062010016322_,5.15252552,0.868542273,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,131868,DB00741,10016322,49,4045,30,3144,0.361670332,1.269475991,0.787827864,2.076705161,0.531460778,DB0074110016322_,0.632125878,0.23860421,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,131875,DB00182,10017577,62,5132,16,2836,0.005853295,2.141189309,1.217780586,3.983354328,0.023214911,DB0018210017577_,3.762960483,0.761361426,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,131876,DB00620,10017577,60,4768,27,3105,0.122610543,1.447082851,0.902260786,2.376619644,0.245165122,DB0062010017577_,1.405823327,0.369549703,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,131877,DB00741,10017577,45,4049,19,3155,0.030597549,1.845323871,1.055260848,3.34774914,0.086022985,DB0074110017577_,2.453140746,0.612654802,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,131887,DB00909,10019211,49,771,12,469,0.004028705,2.482385238,1.28476228,5.182112928,0.017183693,DB0090910019211_,4.063794414,0.909219887,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,zonisamide,DB00909
,131888,DB00182,10020937,80,5114,21,2831,0.001597486,2.108696931,1.287666747,3.599203313,0.008087428,DB0018210020937_,4.817444485,0.746070188,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,131889,DB00620,10020937,53,4775,18,3114,0.014685996,1.920060582,1.104240762,3.490150624,0.048479926,DB0062010020937_,3.026605463,0.652356739,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,triamcinolone,DB00620
,131890,DB00741,10020937,64,4030,21,3153,0.000373529,2.38409991,1.433114102,4.119582255,0.002422154,DB0074110020937_,6.023098001,0.868821657,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,hydrocortisone,DB00741
,131892,DB00956,10020937,77,5737,40,3427,0.502188305,1.149911607,0.772970555,1.733891852,0.663500947,DB0095610020937_,0.410224997,0.139685076,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,131908,DB01076,10022998,47,25700,81,25502,0.002521599,0.575786308,0.392964668,0.835213155,0.011737395,DB0107610022998_,4.444975394,-0.552018679,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,131909,DB00182,10028334,80,5114,26,2826,0.018495341,1.700206538,1.077387722,2.76487395,0.058085911,DB0018210028334_,2.845832148,0.530749737,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,amphetamine,DB00182
,131910,DB00620,10028334,72,4756,27,3105,0.012933736,1.740842994,1.101616286,2.825656521,0.043699068,DB0062010028334_,3.130428514,0.554369475,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,triamcinolone,DB00620
,131912,DB00620,10028372,36,4792,19,3113,0.492204046,1.230813803,0.68610322,2.27601845,0.655117267,DB0062010028372_,0.422941025,0.207675579,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,triamcinolone,DB00620
,131913,DB00741,10028372,38,4056,29,3145,1,1.016032925,0.608737857,1.712321456,1,DB0074110028372_,0,0.015905756,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocortisone,DB00741
,131916,DB00182,10033775,84,5110,16,2836,2.00533926034544e-05,2.913375495,1.689639087,5.340222441,0.000200153,DB0018210033775_,8.516427537,1.069312373,female,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,131917,DB00620,10033775,59,4769,22,3110,0.029212275,1.748772536,1.05308441,3.003963205,0.082959858,DB0062010033775_,2.489398421,0.558914134,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,triamcinolone,DB00620
,131918,DB00741,10033775,36,4058,22,3152,0.426209245,1.270982525,0.726059871,2.27289434,0.594839515,DB0074110033775_,0.519463632,0.239790243,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,hydrocortisone,DB00741
,131920,DB00956,10033775,71,5743,38,3429,0.619742577,1.115592643,0.740273553,1.70466205,0.760412353,DB0095610033775_,0.273894423,0.109385782,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,131939,DB00620,10037884,37,4791,30,3102,0.380629511,0.798570827,0.478933328,1.341468282,0.550699573,DB0062010037884_,0.596565859,-0.224931615,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,triamcinolone,DB00620
,131945,DB00451,10038743,75,47196,28,15391,0.566876715,0.873524595,0.558847214,1.401333245,0.71815789,DB0045110038743_,0.331065832,-0.135218993,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,131951,DB09072,10038743,41,6430,22,2513,0.260132943,0.728381681,0.422873166,1.286685776,0.421449359,DB0907210038743_,0.864055653,-0.316930081,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,sodium oxybate,DB09072
,131965,DB00620,10041349,43,4785,17,3115,0.085407159,1.646529983,0.91779577,3.085218152,0.18738176,DB0062010041349_,1.674607247,0.498670033,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,triamcinolone,DB00620
,131966,DB00741,10041349,44,4050,30,3144,0.638333691,1.138523624,0.69800965,1.880303442,0.775548363,DB0074110041349_,0.254184934,0.129732356,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,hydrocortisone,DB00741
,131967,DB00909,10041349,21,799,35,446,9.67235087077809e-05,0.335216964,0.183010634,0.600383208,0.000774053,DB0090910041349_,7.163870074,-1.092977304,male,10041349,Somnolence,10029205,Nervous system disorders,Nerv,zonisamide,DB00909
,131968,DB00620,10044565,45,4783,15,3117,0.023781648,1.954893862,1.067346772,3.78279807,0.070732744,DB0062010044565_,2.648846669,0.670335902,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,triamcinolone,DB00620
,131969,DB00741,10044565,37,4057,25,3149,0.610076956,1.148719355,0.671653207,1.995304661,0.752290934,DB0074110044565_,0.28463215,0.138647717,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,hydrocortisone,DB00741
,131978,DB00620,10050584,52,4776,17,3115,0.012870975,1.994861068,1.132565971,3.68682033,0.043521398,DB0062010050584_,3.134502553,0.690574408,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,triamcinolone,DB00620
,131979,DB00741,10050584,45,4049,19,3155,0.030597549,1.845323871,1.055260848,3.34774914,0.086022985,DB0074110050584_,2.453140746,0.612654802,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocortisone,DB00741
,131994,DB01076,10050819,42,25705,27,25556,0.091083163,1.546517318,0.931158508,2.609322167,0.196990325,DB0107610050819_,1.624600663,0.436005511,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,131999,DB00331,10019301,28,24918,33,20719,0.198277476,0.705516474,0.41058215,1.204474244,0.347008685,DB0033110019301_,1.05840547,-0.348825157,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,metformin,DB00331
,132012,DB08931,10016322,275,6302,71,2375,0.004509202,1.45968466,1.115472891,1.930940188,0.018802945,DB0893110016322_,3.973741771,0.378220426,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,132018,DB00374,10024670,50,17666,22,5702,0.218715446,0.733571768,0.435710286,1.273311302,0.37196697,DB0037410024670_,0.98895022,-0.309829842,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,treprostinil,DB00374
,132024,DB08931,10055798,65,6512,36,2410,0.055968504,0.668243372,0.436787788,1.036791842,0.136034309,DB0893110055798_,1.994848154,-0.403102842,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,riociguat,DB08931
,132036,DB08931,10066152,127,6450,37,2409,0.214355148,1.281920294,0.879760981,1.908287503,0.366710603,DB0893110066152_,1.003182291,0.248359184,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,riociguat,DB08931
,132040,DB00788,10001551,36,9320,19,5042,1,1.025027276,0.571913311,1.893843935,1,DB0078810001551_,0,0.024719223,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,naproxen,DB00788
,132043,DB00788,10003481,38,9318,17,5044,0.573126937,1.209956825,0.665831112,2.288678516,0.723079655,DB0078810003481_,0.32423589,0.190584677,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,naproxen,DB00788
,132054,DB09072,10035664,61,6410,21,2514,0.711480591,1.139227028,0.682226959,1.974190364,0.828039289,DB0907210035664_,0.188694676,0.130349987,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sodium oxybate,DB09072
,132065,DB09072,10042609,82,6389,24,2511,0.232394744,1.342738822,0.840976887,2.218886205,0.388828508,DB0907210042609_,0.944616887,0.294711425,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,sodium oxybate,DB09072
,132083,DB00996,10020096,56,38897,12,22413,0.000927665,2.688951008,1.424317102,5.512584951,0.005177548,DB0099610020096_,5.263423702,0.989151158,NA,10020096,Hip arthroplasty,10042613,Surgical and medical procedures,Surg,gabapentin,DB00996
,132086,DB00996,10023469,59,38894,21,22404,0.062709834,1.618349404,0.96858385,2.804995833,0.148504706,DB0099610023469_,1.907138633,0.481406743,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,gabapentin,DB00996
,132092,DB00186,10039073,55,16846,6,10002,1.86606173033145e-06,5.441506665,2.345738711,15.47829249,2.49234921655295e-05,DB0018610039073_,10.59969974,1.694055983,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,132093,DB00588,10039073,110,16414,16,8452,7.3932834225201e-08,3.539979101,2.083884494,6.414099999,1.37629217252791e-06,DB0058810039073_,13.49611751,1.264120824,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,132128,DB00650,10043554,48,2083,104,1910,5.47593983396712e-07,0.423289102,0.292492343,0.605155697,8.41501125997478e-06,DB0065010043554_,11.68549339,-0.859699878,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,leucovorin,DB00650
,132158,DB01132,10005003,33,1252,151,1379,5.50110277850275e-16,0.240835567,0.158730947,0.355970531,3.78524833855876e-14,DB0113210005003_,30.90507981,-1.423640871,male,10005003,Bladder cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pioglitazone,DB01132
,132229,DB00874,10000081,41,3294,27,1949,0.705352221,0.898500468,0.53765562,1.524069164,0.82344088,DB0087410000081_,0.194263523,-0.107028052,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,guaifenesin,DB00874
,132236,DB00874,10002855,58,3277,21,1955,0.059898248,1.647558574,0.981373599,2.867319562,0.143292419,DB0087410002855_,1.942867845,0.49929454,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,guaifenesin,DB00874
,132247,DB00874,10003988,57,3278,31,1945,0.739719894,1.09099236,0.68981548,1.754885354,0.850288075,DB0087410003988_,0.162180075,0.087087704,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,guaifenesin,DB00874
,132329,DB00635,10069868,106,32947,37,23757,8.39959615832154e-05,2.06572094,1.408028872,3.091707555,0.000687477,DB0063510069868_,7.28248152,0.725479289,NA,10069868,Device issue,10077536,Product issues,Prod,prednisone,DB00635
,132341,DB09035,10013968,203,4523,227,6463,0.014386804,1.277802513,1.048045784,1.557178838,0.047638844,DB0903510013968_,3.044106795,0.245141816,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nivolumab,DB09035
,132342,DB01296,10037660,35,1414,15,968,0.14629446,1.597066502,0.844463806,3.165729954,0.278800402,DB0129610037660_,1.277259159,0.46816851,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,glucosamine,DB01296
,132348,DB01060,10002855,144,8443,43,5038,3.50637593959904e-05,1.998181426,1.409720604,2.883931528,0.000325269,DB0106010002855_,8.030856719,0.69223748,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,amoxicillin,DB01060
,132370,DB00186,10009887,83,16818,36,9972,0.128389644,1.367031848,0.913247952,2.083361914,0.253357493,DB0018610009887_,1.372953773,0.312641855,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,132371,DB00193,10009887,57,19263,35,8667,0.175032794,0.732735093,0.472388131,1.151219005,0.317510477,DB0019310009887_,1.147244462,-0.310971043,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,132404,DB00451,10005395,84,47187,15,15404,0.026652324,1.827997303,1.047332653,3.411457687,0.077226076,DB0045110005395_,2.56101811,0.603220997,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,132408,DB01373,10005395,93,22627,25,7356,0.453436689,1.209353589,0.770015005,1.965137792,0.620985952,DB0137310005395_,0.476446819,0.190085993,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,calcium,DB01373
,132409,DB00761,10019303,108,15199,51,8574,0.32050048,1.194559048,0.847649586,1.702930353,0.488680035,DB0076110019303_,0.716047328,0.17777712,NA,10019303,Heart rate increased,10022891,Investigations,Inv,potassium chloride,DB00761
,132434,DB00316,10002948,113,65361,66,36887,0.815722383,0.966221294,0.706809018,1.330087449,0.901212667,DB0031610002948_,0.104014015,-0.034362388,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,132442,DB01156,10002948,45,13577,12,6316,0.088280406,1.744450833,0.906794139,3.625528305,0.192384901,DB0115610002948_,1.648257223,0.556439797,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,132460,DB01156,10014625,59,13563,21,6307,0.336176617,1.30640614,0.781345708,2.265994281,0.505257999,DB0115610014625_,0.682686091,0.267279963,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,132464,DB00404,10057668,75,19817,26,9836,0.137721142,1.431738157,0.905008225,2.332422288,0.266519434,DB0040410057668_,1.322308116,0.3588892,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,132468,DB00999,10057668,50,21380,29,12210,1,0.984640153,0.610735341,1.614688765,1,DB0099910057668_,0,-0.015479031,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,132472,DB00783,10011906,124,16590,12,361,4.38053000579051e-05,0.224901936,0.122810013,0.451159558,0.000394999,DB0078310011906_,7.836627128,-1.492090813,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,estradiol,DB00783
,132490,DB01409,10020919,45,5986,25,3941,0.541371252,1.185012614,0.710017441,2.020092159,0.696726565,DB0140910020919_,0.361362248,0.169753419,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,tiotropium,DB01409
,132495,DB00338,10039163,63,33611,30,22242,0.167753302,1.389661728,0.88589156,2.224688607,0.307864936,DB0033810039163_,1.178094113,0.329060356,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,omeprazole,DB00338
,132500,DB00343,10064911,109,8627,41,5054,0.016890238,1.557416908,1.076308598,2.292118771,0.054131551,DB0034310064911_,2.916338066,0.44302862,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,132503,DB01222,10064911,55,9219,23,5382,0.196377525,1.39599955,0.842684403,2.383108886,0.344612827,DB0122210064911_,1.065333731,0.333610682,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,132504,DB01409,10064911,54,5977,23,3943,0.080380932,1.548784776,0.932813665,2.648817553,0.179044346,DB0140910064911_,1.720121761,0.437470608,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tiotropium,DB01409
,132509,DB00973,10042772,21,3830,38,2983,0.002168325,0.430467586,0.239457214,0.754179,0.010398546,DB0097310042772_,4.566089291,-0.842883251,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,ezetimibe,DB00973
,132529,DB00316,10016059,54,65420,6,36947,5.75499905379854e-06,5.082115063,2.189084942,14.46216804,6.68301966552218e-05,DB0031610016059_,9.613355534,1.625727526,female,10016059,Facial pain,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,132542,DB00193,10058920,38,19282,27,8675,0.080276172,0.633205229,0.376342461,1.079159043,0.178861793,DB0019310058920_,1.721141879,-0.456960692,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,132543,DB00316,10058920,88,65386,31,36922,0.021970195,1.602947825,1.053327995,2.49886437,0.066561445,DB0031610058920_,2.709629773,0.471844325,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,132549,DB00316,10061368,52,65422,29,36924,1,1.012022837,0.630547483,1.653640927,1,DB0031610061368_,0,0.011951136,NA,10061368,Spinal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,132594,DB00230,10006002,72,19602,20,8631,0.069907039,1.585100543,0.954176188,2.749053224,0.161128247,DB0023010006002_,1.825554669,0.46064784,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,132596,DB00108,10011224,49,10145,21,3274,0.267230245,0.753031723,0.442444315,1.324038601,0.429506358,DB0010810011224_,0.845118733,-0.283647923,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,natalizumab,DB00108
,132599,DB00230,10015958,52,19622,11,8640,0.027499822,2.081476689,1.072262982,4.426179034,0.079101862,DB0023010015958_,2.537018862,0.733077588,NA,10015958,Eye pain,10015919,Eye disorders,Eye,pregabalin,DB00230
,132622,DB00230,10043554,33,19641,32,8619,0.001724426,0.452546504,0.269545261,0.760691411,0.008603457,DB0023010043554_,4.75559122,-0.79286475,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,pregabalin,DB00230
,132637,DB00009,10019211,38,1313,45,1506,0.911533119,0.96857604,0.607891605,1.536178712,0.960287291,DB0000910019211_,0.040522778,-0.031928286,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,alteplase,DB00009
,132640,DB00009,10047700,47,1304,62,1489,0.49412431,0.865655269,0.575176673,1.295451527,0.656739251,DB0000910047700_,0.420468218,-0.144268522,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,alteplase,DB00009
,132648,DB00104,10003549,38,1443,20,1057,0.282007807,1.3915776,0.784422994,2.539750443,0.445989905,DB0010410003549_,0.807458961,0.330438067,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,octreotide,DB00104
,132665,DB00734,10047700,71,3979,46,4856,0.00098486,1.883512132,1.278405687,2.798958376,0.00543503,DB0073410047700_,5.2148903,0.633138189,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,risperidone,DB00734
,132669,DB00695,10002383,38,28011,54,20474,0.00201554,0.514373721,0.330304117,0.793791488,0.009787266,DB0069510002383_,4.626673113,-0.664805194,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,furosemide,DB00695
,132673,DB00227,10002855,39,2428,20,1783,0.232246367,1.431863228,0.811855671,2.600605736,0.388666842,DB0022710002855_,0.94503275,0.358976553,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,lovastatin,DB00227
,132674,DB00246,10002855,45,1029,21,680,0.202404312,1.415809115,0.81758334,2.52601889,0.35179503,DB0024610002855_,1.044706573,0.347701181,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ziprasidone,DB00246
,132689,DB01067,10005483,13,4348,43,4780,0.000233435,0.33242335,0.163752207,0.630798027,0.001638624,DB0106710005483_,6.41389866,-1.101345973,male,10005483,Blood creatinine increased,10022891,Investigations,Inv,glipizide,DB01067
,132692,DB00335,10005557,77,8389,50,5415,1,0.994051436,0.686166627,1.451385843,1,DB0033510005557_,0,-0.005966327,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,atenolol,DB00335
,132741,DB01067,10027175,47,4314,17,4806,4.03119280211489e-05,3.07966103,1.732773573,5.729204103,0.000367151,DB0106710027175_,7.909736178,1.124819536,female,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,glipizide,DB01067
,132770,DB00404,10038428,45,19847,26,9836,0.530001461,0.857767766,0.517587189,1.449160942,0.687165262,DB0040410038428_,0.375180459,-0.153421886,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,alprazolam,DB00404
,132776,DB00335,10041349,134,8332,59,5406,0.014118325,1.47355994,1.074841134,2.041128028,0.04690736,DB0033510041349_,3.059580678,0.387681201,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,132777,DB01261,10041349,40,3741,20,3283,0.050367083,1.755005808,0.999685711,3.175686483,0.125702504,DB0126110041349_,2.073837244,0.562472166,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,sitagliptin,DB01261
,132784,DB00335,10042458,42,8424,11,5454,0.006799519,2.471877098,1.249387129,5.328732255,0.026193491,DB0033510042458_,3.642244322,0.904977821,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,atenolol,DB00335
,132790,DB00695,10042727,49,28000,19,20509,0.019050591,1.888952968,1.091650872,3.398807448,0.059480507,DB0069510042727_,2.82210664,0.63602269,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,132808,DB00404,10061520,42,19850,8,9854,0.009892422,2.606148979,1.208126192,6.429281078,0.035252483,DB0040410061520_,3.345219305,0.957873645,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,132810,DB00722,10061520,57,25346,31,26001,0.003898026,1.886190872,1.196983383,3.023667236,0.01670764,DB0072210061520_,4.091889164,0.634559384,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,132825,DB00335,10065154,50,8416,25,5440,0.343126084,1.292745651,0.783661917,2.183544756,0.512447526,DB0033510065154_,0.668556962,0.256768368,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,atenolol,DB00335
,132826,DB00437,10065154,39,6882,66,11480,1,0.98570751,0.645140452,1.488156693,1,DB0043710065154_,0,-0.014395611,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,allopurinol,DB00437
,132828,DB00722,10065154,159,25244,144,25888,0.299694531,1.132331626,0.897429165,1.429713004,0.465709178,DB0072210065154_,0.764193921,0.124278893,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,lisinopril,DB00722
,132837,DB00863,10016288,41,10632,43,5797,0.002871713,0.51988616,0.330103368,0.817753929,0.013048274,DB0086310016288_,4.339099405,-0.654145414,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,ranitidine,DB00863
,132852,DB00695,10003119,77,27972,69,20459,0.240201247,0.816219383,0.581762454,1.147050951,0.398073096,DB0069510003119_,0.921119633,-0.203072108,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,furosemide,DB00695
,132860,DB00619,10010774,38,2861,28,2466,0.619649859,1.169736421,0.696945453,1.985184049,0.760331312,DB0061910010774_,0.274001004,0.156778442,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,imatinib,DB00619
,132880,DB00695,10039674,45,28004,13,20515,0.00202116,2.535758954,1.343861203,5.124755099,0.009809118,DB0069510039674_,4.624442901,0.930492982,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,132901,DB00915,10016256,126,1329,46,1005,2.74694271913585e-05,2.070755403,1.450542956,2.999901628,0.000262558,DB0091510016256_,8.245039388,0.72791347,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,amantadine,DB00915
,132902,DB00915,10019211,56,1399,16,1035,0.000593053,2.588437314,1.453803176,4.86342492,0.003561839,DB0091510019211_,5.637478183,0.95105434,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,amantadine,DB00915
,132913,DB01015,10021789,129,9758,101,9280,0.163324774,1.214648341,0.927383705,1.594612993,0.301834472,DB0101510021789_,1.197876519,0.194454604,NA,10021789,Infection,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,132914,DB09140,10021789,67,3674,19,1779,0.047691998,1.707340674,1.009613742,3.019853446,0.120745922,DB0914010021789_,2.114066759,0.534936999,NA,10021789,Infection,10021881,Infections and infestations,Infec,oxygen,DB09140
,132916,DB00588,10030124,241,16283,108,8360,0.254993899,1.145667712,0.907876624,1.453551736,0.415724276,DB0058810030124_,0.877733037,0.135987622,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,132917,DB00697,10030124,45,6051,10,1796,0.519122443,1.335590943,0.661886277,2.978666391,0.678339262,DB0069710030124_,0.38810773,0.289373848,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,132952,DB00181,10047899,131,9725,26,5845,1.58120033176881e-08,3.028068,1.973701236,4.81382963,3.39141988743723e-07,DB0018110047899_,14.89684697,1.107924792,female,10047899,Weight increased,10022891,Investigations,Inv,baclofen,DB00181
,132955,DB00813,10047899,82,10490,32,10136,7.54483069222297e-06,2.476102615,1.625449372,3.854885411,8.47866074155968e-05,DB0081310047899_,9.375372959,0.906685798,NA,10047899,Weight increased,10022891,Investigations,Inv,fentanyl,DB00813
,132960,DB00497,10056812,51,19216,26,16349,0.038724722,1.668851733,1.020775803,2.789896355,0.103092047,DB0049710056812_,2.272133034,0.512135805,NA,10056812,Body height decreased,10022891,Investigations,Inv,oxycodone,DB00497
,132967,DB00996,10056812,77,38876,40,22385,0.63192058,1.108437272,0.746753073,1.667892524,0.770695641,DB0099610056812_,0.260461743,0.102951161,NA,10056812,Body height decreased,10022891,Investigations,Inv,gabapentin,DB00996
,132968,DB00999,10056812,62,21368,17,12222,0.006668405,2.08598996,1.203507587,3.808025999,0.025778222,DB0099910056812_,3.658225264,0.735243543,NA,10056812,Body height decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,132974,DB00480,10062016,41,67387,43,67619,0.913186312,0.956758405,0.608155379,1.503167133,0.961104948,DB0048010062016_,0.039671669,-0.04420437,NA,10062016,Immunosuppression,10021428,Immune system disorders,Immun,lenalidomide,DB00480
,132986,DB01234,10062016,23,31602,32,32856,0.345064483,0.74727623,0.417480097,1.317895914,0.514523481,DB0123410062016_,0.664514086,-0.291320376,NA,10062016,Immunosuppression,10021428,Immune system disorders,Immun,dexamethasone,DB01234
,132989,DB00169,10065553,36,38655,20,18155,0.567290872,0.845417138,0.476313678,1.54179683,0.718475502,DB0016910065553_,0.33062367,-0.167925119,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,132991,DB00480,10065553,109,67319,120,67542,0.50860258,0.911355868,0.69645468,1.191424233,0.669116786,DB0048010065553_,0.401796667,-0.092821823,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,lenalidomide,DB00480
,133000,DB01234,10065553,72,31553,71,32817,0.80178884,1.054730051,0.748964428,1.485614621,0.892794236,DB0123410065553_,0.113399143,0.053284858,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,dexamethasone,DB01234
,133027,DB01104,10007739,42,15421,11,7275,0.103670934,1.801221199,0.910730212,3.881642859,0.216514371,DB0110410007739_,1.530098356,0.588464879,NA,10007739,Cataract,10015919,Eye disorders,Eye,sertraline,DB01104
,133036,DB05351,10033425,61,2662,15,1116,0.07416574,1.704674053,0.952244108,3.243891914,0.168476924,DB0535110033425_,1.780956491,0.533373921,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,dexlansoprazole,DB05351
,133038,DB01261,10047513,50,3731,32,3271,0.182066723,1.36979441,0.859391807,2.21206957,0.326474319,DB0126110047513_,1.119403989,0.314660663,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,sitagliptin,DB01261
,133041,DB00374,10042682,86,17630,19,5705,0.13983204,1.464646757,0.882597449,2.552444077,0.269592193,DB0037410042682_,1.310844858,0.381614092,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,133048,DB01104,10040979,49,15414,18,7268,0.431871716,1.283525316,0.733872765,2.343129972,0.600335716,DB0110410040979_,0.510266253,0.249610445,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,133056,DB01261,10002034,80,3701,88,3215,0.137298306,0.789742748,0.573775289,1.08561069,0.265955707,DB0126110002034_,1.324425498,-0.236048022,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,sitagliptin,DB01261
,133059,DB00331,10012218,61,24885,42,20710,0.373332217,1.208706689,0.802317889,1.836417974,0.543056853,DB0033110012218_,0.610541264,0.189550936,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,metformin,DB00331
,133063,DB06655,10013709,82,3606,46,2073,0.926293907,1.024774267,0.702645835,1.5104931,0.968674572,DB0665510013709_,0.031826563,0.024472361,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,liraglutide,DB06655
,133064,DB01276,10019211,34,1983,22,1489,0.683438838,1.160388796,0.656192221,2.092003134,0.808636124,DB0127610019211_,0.212406248,0.148755118,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,exenatide,DB01276
,133071,DB06655,10022437,34,3654,18,2101,0.885206982,1.08607982,0.594678173,2.048096927,0.952183569,DB0665510022437_,0.048997438,0.082574718,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,liraglutide,DB06655
,133081,DB01261,10030124,58,3723,48,3255,0.844620705,1.056447271,0.706019538,1.587144109,0.92150127,DB0126110030124_,0.081751124,0.054911648,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,133087,DB01261,10035598,32,3749,39,3264,0.188220019,0.714404355,0.432178494,1.173251258,0.334307298,DB0126110035598_,1.095694656,-0.336306153,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sitagliptin,DB01261
,133092,DB00331,10041101,23,24923,31,20721,0.099908956,0.616860217,0.343351659,1.093165194,0.210636207,DB0033110041101_,1.557622773,-0.483112833,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,133115,DB00331,10061623,152,24794,131,20621,0.765047918,0.965005056,0.758306136,1.229481262,0.870359749,DB0033110061623_,0.138848648,-0.035621939,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,133119,DB00331,10066901,42,24904,48,20704,0.138638844,0.727444514,0.468886967,1.124687813,0.267871362,DB0033110066901_,1.317248407,-0.318217552,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,133127,DB00795,10003988,74,4495,24,1479,1,1.014517137,0.629945044,1.688225512,1,DB0079510003988_,0,0.014412773,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfasalazine,DB00795
,133129,DB00005,10053181,61,128021,36,42383,0.009218442,0.560975409,0.36558382,0.872140481,0.03335491,DB0000510053181_,3.400550278,-0.578078209,NA,10053181,Therapeutic response delayed,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,133148,DB00950,10008479,78,4640,21,2035,0.047570369,1.628896724,0.992325057,2.785567992,0.120519242,DB0095010008479_,2.115945853,0.487902929,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,133158,DB00950,10020772,80,4638,21,2035,0.03791783,1.671378681,1.019858068,2.85459342,0.101482959,DB0095010020772_,2.287864382,0.513648843,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,fexofenadine,DB00950
,133271,DB01261,10020635,22,3759,36,3267,0.023852533,0.531178159,0.297028728,0.929862091,0.070887424,DB0126110020635_,2.646662243,-0.632657799,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,sitagliptin,DB01261
,133272,DB01261,10029331,50,3731,40,3263,0.749960635,1.093157907,0.70486207,1.705182343,0.858399499,DB0126110029331_,0.152685672,0.08907067,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,sitagliptin,DB01261
,133278,DB00484,10007739,31,2476,22,1758,1,1.000496073,0.558794339,1.820121407,1,DB0048410007739_,0,0.00049595,NA,10007739,Cataract,10015919,Eye disorders,Eye,brimonidine,DB00484
,133284,DB00484,10018304,54,2453,23,1757,0.036211273,1.68147022,1.010202459,2.882154783,0.097953412,DB0048410018304_,2.323263298,0.519668542,NA,10018304,Glaucoma,10015919,Eye disorders,Eye,brimonidine,DB00484
,133285,DB00654,10018304,51,3765,39,2559,0.590150529,0.888832343,0.572468404,1.389563656,0.73676613,DB0065410018304_,0.305484764,-0.117846651,NA,10018304,Glaucoma,10015919,Eye disorders,Eye,latanoprost,DB00654
,133306,DB06724,10007739,58,7871,18,3901,0.08721534,1.596929648,0.92603243,2.884198574,0.190458622,DB0672410007739_,1.658320314,0.468082816,NA,10007739,Cataract,10015919,Eye disorders,Eye,calcium carbonate,DB06724
,133311,DB00207,10013911,34,9046,18,5437,0.774517897,1.135310242,0.622724839,2.137438933,0.87707399,DB0020710013911_,0.131163923,0.126905955,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,133317,DB06643,10013911,86,52335,39,7476,3.53247303931636e-08,0.315006411,0.213205323,0.472846134,7.02618644256e-07,DB0664310013911_,14.16845156,-1.155162289,male,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,133319,DB09270,10013911,28,3086,30,2338,0.230113194,0.707162353,0.405863096,1.228608019,0.38608019,DB0927010013911_,0.951710184,-0.346495003,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,ubidecarenone,DB09270
,133325,DB01062,10029331,32,4454,32,1713,0.000207159,0.384665636,0.227402717,0.650733071,0.001483496,DB0106210029331_,6.513354116,-0.955380799,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,133326,DB01306,10029331,36,4172,63,3803,0.00164492,0.520933612,0.335117684,0.798908156,0.008283692,DB0130610029331_,4.79346651,-0.65213267,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,insulin aspart,DB01306
,133327,DB06724,10029331,132,7797,64,3855,0.939077193,1.019741894,0.748965101,1.400540927,0.978713508,DB0672410029331_,0.021516317,0.019549551,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,133330,DB00254,10035528,34,5901,29,3359,0.11560502,0.66742711,0.393851236,1.137756962,0.234583544,DB0025410035528_,1.449943488,-0.404325094,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,doxycycline,DB00254
,133332,DB00331,10035528,165,24781,167,20585,0.076677641,0.820734936,0.657280195,1.02476228,0.17266839,DB0033110035528_,1.756382345,-0.197555077,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,metformin,DB00331
,133335,DB01062,10035528,34,4452,21,1724,0.097792269,0.627014169,0.352450637,1.140308731,0.207561418,DB0106210035528_,1.572327991,-0.46678614,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,oxybutynin,DB01062
,133338,DB13961,10035528,97,9360,73,6341,0.529809919,0.900190387,0.656406564,1.239070634,0.68702781,DB1396110035528_,0.375380507,-0.105148997,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,fish oil,DB13961
,133388,DB00480,10043414,115,67313,86,67576,0.040603189,1.342426303,1.006152289,1.796768995,0.106853706,DB0048010043414_,2.236294616,0.29447865,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,133392,DB01234,10043414,66,31559,79,32809,0.406928197,0.868536017,0.616509571,1.220267421,0.576440054,DB0123410043414_,0.550883927,-0.140946224,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,133399,DB00169,10049040,46,38645,31,18144,0.14149165,0.696674845,0.432209303,1.136974026,0.271924745,DB0016910049040_,1.302229925,-0.361436483,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,133404,DB00316,10049040,63,65411,50,36903,0.077581356,0.710883929,0.482520737,1.052123776,0.174255582,DB0031610049040_,1.747232193,-0.341246112,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,133406,DB00338,10049040,37,33637,31,22241,0.38565626,0.789194277,0.476266273,1.315832429,0.555770432,DB0033810049040_,0.587399962,-0.236742757,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,133407,DB00381,10049040,31,29329,22,22865,0.783031529,1.098560987,0.615694225,1.991799352,0.881832675,DB0038110049040_,0.125752951,0.09400113,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,133408,DB00480,10049040,68,67360,87,67575,0.147859331,0.78410726,0.562252767,1.089584007,0.281018258,DB0048010049040_,1.269335636,-0.243209456,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,133410,DB00695,10049040,52,27997,23,20505,0.046472143,1.655839542,0.99522837,2.835701117,0.118459596,DB0069510049040_,2.133183342,0.504308156,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,133412,DB00722,10049040,21,25382,30,26002,0.264024219,0.717105999,0.390109534,1.295262189,0.42591608,DB0072210049040_,0.853512947,-0.332531612,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,133416,DB01234,10049040,42,31583,65,32823,0.052435264,0.671529916,0.444210173,1.005392623,0.129581916,DB0123410049040_,2.04344204,-0.398196713,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,133477,DB00422,10001760,51,3384,8,2941,1.1899378560219e-07,5.539224812,2.603696936,13.54276603,2.12699874502112e-06,DB0042210001760_,13.06079861,1.711854565,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,methylphenidate,DB00422
,133488,DB00158,10004146,44,16771,26,8078,0.443506408,0.815150131,0.490557659,1.380050267,0.611608611,DB0015810004146_,0.491662725,-0.204382973,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,folic acid,DB00158
,133494,DB00451,10021519,118,47153,25,15394,0.05150468,1.540884025,0.993944516,2.478122234,0.12782964,DB0045110021519_,2.057056841,0.432356294,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,133503,DB00115,10022052,96,18329,12,10460,4.42778626858354e-09,4.565021595,2.495110941,9.147895604,1.07663609685216e-07,DB0011510022052_,16.0442542,1.518423245,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,133505,DB01098,10022052,41,8108,9,7200,2.51555907776103e-05,4.044948281,1.934800894,9.470885552,0.000242826,DB0109810022052_,8.323166168,1.397468764,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,133507,DB00115,10040753,363,18062,94,10378,3.29485069323397e-13,2.218785297,1.761503006,2.818128185,1.57750729456566e-11,DB0011510040753_,24.87259008,0.796959883,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,133508,DB00186,10040753,203,16698,52,9956,7.17963470931106e-09,2.327556117,1.706892141,3.223891427,1.66416841564587e-07,DB0018610040753_,15.6087701,0.84481884,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,lorazepam,DB00186
,133509,DB00567,10040753,90,4429,26,2055,0.034105336,1.606005171,1.024569476,2.598001721,0.093605486,DB0056710040753_,2.368666288,0.473749835,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,cephalexin,DB00567
,133510,DB01592,10040753,143,6133,20,3047,1.86329891345168e-09,3.551900182,2.210706795,6.001979006,4.89034567549451e-08,DB0159210040753_,16.83341775,1.267482723,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,iron,DB01592
,133518,DB00203,10040070,74,13804,35,8903,0.140569931,1.363607317,0.899582962,2.102888924,0.270627748,DB0020310040070_,1.307011027,0.310133627,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,sildenafil,DB00203
,133521,DB00424,10033371,57,1137,11,417,0.050066189,1.899811359,0.97414165,4.057459381,0.125135717,DB0042410033371_,2.078356392,0.641754596,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,hyoscyamine,DB00424
,133528,DB06605,10005750,94,13979,45,12988,0.000227203,1.940749533,1.345413145,2.836429567,0.001603877,DB0660510005750_,6.435331722,0.663074256,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,apixaban,DB06605
,133530,DB06605,10013710,94,13979,117,12916,0.032138423,0.742336597,0.559113153,0.983376427,0.089398683,DB0660510013710_,2.414649326,-0.297952504,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,133535,DB00193,10001551,66,19254,22,8680,0.249088305,1.352484924,0.823163625,2.30343189,0.408490522,DB0019310001551_,0.895286567,0.301943585,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,tramadol,DB00193
,133539,DB00588,10001551,53,16471,31,8437,0.564873759,0.875764914,0.551480476,1.412594973,0.716501714,DB0058810001551_,0.33337464,-0.132657587,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,133540,DB00695,10001551,109,27940,95,20433,0.227339558,0.839096791,0.631009611,1.117410089,0.382598859,DB0069510001551_,0.960768203,-0.175429214,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,furosemide,DB00695
,133543,DB00193,10003481,69,19251,21,8681,0.137379597,1.481649454,0.897296905,2.544843362,0.266064154,DB0019310003481_,1.324017819,0.393155963,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,tramadol,DB00193
,133546,DB00588,10003481,51,16473,33,8435,0.300114677,0.791377488,0.500483931,1.266906174,0.466210471,DB0058810003481_,0.763118092,-0.233980196,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,133547,DB00695,10003481,146,27903,90,20438,0.209761589,1.188206753,0.906938541,1.563872288,0.360883843,DB0069510003481_,1.019199136,0.17244524,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,furosemide,DB00695
,133548,DB01137,10003481,29,7743,34,5559,0.055116244,0.61239651,0.359457349,1.03699652,0.134541021,DB0113710003481_,2.005886137,-0.490375315,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,levofloxacin,DB01137
,133550,DB00009,10013709,64,1287,70,1481,0.790748969,1.052112662,0.731342007,1.511317355,0.88663055,DB0000910013709_,0.1203269,0.050800201,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,alteplase,DB00009
,133552,DB09153,10035226,43,7756,35,5664,0.647011709,0.897201412,0.560090497,1.446183295,0.782313016,DB0915310035226_,0.245500343,-0.108474902,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sodium chloride,DB09153
,133554,DB00327,10043607,42,6096,29,4233,1,1.005667481,0.610733526,1.677006192,1,DB0032710043607_,0,0.005651481,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,hydromorphone,DB00327
,133556,DB09153,10051055,30,7769,30,5669,0.239500842,0.729722116,0.424468408,1.254471797,0.397328935,DB0915310051055_,0.922990791,-0.31509148,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,sodium chloride,DB09153
,133561,DB00682,10059570,34,19425,16,16348,0.063950444,1.788358605,0.960137005,3.470874989,0.150567666,DB0068210059570_,1.89334269,0.581298219,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,warfarin,DB00682
,133562,DB00722,10059570,42,25361,23,26009,0.017710736,1.872710476,1.100402177,3.263192478,0.056174381,DB0072210059570_,2.879294485,0.627386834,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,lisinopril,DB00722
,133563,DB00761,10059570,44,15263,21,8604,0.605560346,1.181086522,0.686924653,2.092701551,0.748654988,DB0076110059570_,0.289477031,0.166434796,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,potassium chloride,DB00761
,133571,DB00203,10019301,43,13835,22,8916,0.44559595,1.259581849,0.73641638,2.212520123,0.613465694,DB0020310019301_,0.488630935,0.2307798,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,sildenafil,DB00203
,133580,DB00482,10035664,139,8120,61,3010,0.296601854,0.844722201,0.618852793,1.164481973,0.462434293,DB0048210035664_,0.771250802,-0.168747462,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,celecoxib,DB00482
,133581,DB01394,10035664,49,1391,64,1939,0.771414448,1.067227753,0.715458116,1.58361221,0.874859937,DB0139410035664_,0.133691477,0.065064401,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,colchicine,DB01394
,133617,DB00996,10058467,31,38922,22,22403,0.476811104,0.811068661,0.454603555,1.47055192,0.642157087,DB0099610058467_,0.442922322,-0.209402567,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,gabapentin,DB00996
,133626,DB09033,10028813,103,2521,50,1619,0.128225059,1.322859197,0.928948049,1.904896456,0.253139854,DB0903310028813_,1.37381316,0.279795453,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,vedolizumab,DB09033
,133627,DB09033,10047700,59,2565,22,1647,0.028990917,1.721804501,1.034654296,2.963194012,0.08246151,DB0903310047700_,2.495423637,0.543372869,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,vedolizumab,DB09033
,133645,DB00373,10047571,39,1793,21,1266,0.355600506,1.311178232,0.74844886,2.358109856,0.525331421,DB0037310047571_,0.643725937,0.270926147,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,timolol,DB00373
,133729,DB00497,10000381,88,19179,99,16276,0.055977877,0.754354394,0.559093498,1.016400194,0.136043501,DB0049710000381_,1.994780583,-0.281893003,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,133732,DB00575,10010305,58,5186,63,3766,0.032675619,0.668595129,0.458611368,0.973187398,0.090584681,DB0057510010305_,2.401470159,-0.40257659,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,clonidine,DB00575
,133740,DB00575,10016322,94,5150,46,3783,0.024897203,1.500997242,1.041253193,2.190503169,0.073261481,DB0057510016322_,2.6137203,0.406129715,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,133744,DB00327,10019063,64,6074,44,4218,1,1.010087029,0.675999315,1.521424951,1,DB0032710019063_,0,0.010036494,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,hydromorphone,DB00327
,133745,DB00575,10019063,38,5206,42,3787,0.068723724,0.658194702,0.41212753,1.048127754,0.159021355,DB0057510019063_,1.838716776,-0.418254491,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,clonidine,DB00575
,133757,DB01068,10021097,236,13527,135,6705,0.200660472,0.866527722,0.696905372,1.080992436,0.349781849,DB0106810021097_,1.050445608,-0.143261177,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,clonazepam,DB01068
,133773,DB01413,10037844,36,1184,43,1616,0.565804231,1.142621593,0.708148355,1.834186935,0.71730119,DB0141310037844_,0.332259457,0.133325265,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cefepime,DB01413
,133774,DB00413,10010264,58,2141,30,1177,0.822358729,1.062823104,0.668412503,1.721289988,0.905540277,DB0041310010264_,0.099223522,0.060928674,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,pramipexole,DB00413
,133776,DB06413,10010264,63,1493,31,643,0.566776184,0.875308281,0.554633023,1.406834028,0.718094183,DB0641310010264_,0.331154544,-0.133179134,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,armodafinil,DB06413
,133789,DB00482,10039073,157,8102,27,3044,7.46669899373429e-05,2.184558642,1.44203838,3.426941891,0.000620396,DB0048210039073_,7.385153041,0.781413814,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,133813,DB00073,10043414,43,7363,21,6386,0.032384225,1.775843055,1.029731173,3.154000665,0.089938123,DB0007310043414_,2.408633365,0.574275271,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,133815,DB00343,10016766,41,8695,15,5080,0.12821137,1.596882116,0.864354865,3.109115821,0.253129219,DB0034310016766_,1.373855173,0.468053051,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,133816,DB00421,10016766,45,8858,15,5237,0.06020717,1.773583692,0.969169473,3.429020612,0.143848155,DB0042110016766_,1.938997016,0.573002184,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,133818,DB00950,10016766,34,4684,17,2039,0.647928352,0.870651753,0.471805451,1.66589397,0.782971139,DB0095010016766_,0.244659444,-0.138513206,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,fexofenadine,DB00950
,133819,DB06228,10016766,50,15862,33,16043,0.06157291,1.532411679,0.967371829,2.456836345,0.14633208,DB0622810016766_,1.921876722,0.426842755,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,133838,DB01224,10050584,45,8063,18,5899,0.029673199,1.828951245,1.036591541,3.360739825,0.083984068,DB0122410050584_,2.477128166,0.603742713,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,133844,DB00005,10022088,46,128036,14,42405,0.881778872,1.088214098,0.587748167,2.143666285,0.950542688,DB0000510022088_,0.050722207,0.084537911,NA,10022088,Injection site paraesthesia,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,133854,DB01115,10033425,106,3494,31,2237,8.11407445995473e-05,2.188939803,1.4491593,3.393067651,0.000667329,DB0111510033425_,7.312226917,0.783417318,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,nifedipine,DB01115
,133855,DB01202,10033425,60,6654,41,5677,0.316228577,1.248519612,0.824092243,1.908403466,0.483892775,DB0120210033425_,0.725891935,0.221958539,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,levetiracetam,DB01202
,133856,DB00590,10048959,22,754,44,1908,0.407200186,1.265174072,0.716915895,2.173719431,0.576751739,DB0059010048959_,0.550343367,0.235209719,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,doxazosin,DB00590
,133862,DB09053,10012174,36,2249,66,3986,0.917482104,0.966736173,0.623361392,1.477955868,0.963349796,DB0905310012174_,0.037338698,-0.033829651,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ibrutinib,DB09053
,133899,DB00924,10022086,124,10038,24,4227,0.000258881,2.175584484,1.394542615,3.528699716,0.001788589,DB0092410022086_,6.326328466,0.777297357,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,133901,DB01240,10003988,244,5507,47,1529,0.023811196,1.441311009,1.045188807,2.024504043,0.070808608,DB0124010003988_,2.6477747,0.365553122,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,epoprostenol,DB01240
,133904,DB14126,10011906,15,956,49,1227,0.001212626,0.393055346,0.203413857,0.717940988,0.006456983,DB1412610011906_,5.042593125,-0.933804848,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tenofovir,DB14126
,133908,DB00563,10013950,119,46527,37,15311,0.852661215,1.058364602,0.72599177,1.575759268,0.92790693,DB0056310013950_,0.074823843,0.056724889,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,133911,DB01234,10024774,69,31556,98,32790,0.052416837,0.731620676,0.529502441,1.006145834,0.12955725,DB0123410024774_,2.043632412,-0.312493102,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,133912,DB08910,10024774,52,16692,86,17402,0.00816104,0.630381632,0.437619509,0.900371874,0.030281329,DB0891010024774_,3.497223959,-0.461429878,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,133915,DB00285,10022086,103,10848,19,3699,0.011851063,1.84852356,1.123823376,3.199233262,0.040770263,DB0028510022086_,3.199802322,0.614387245,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,133924,DB06403,10038683,47,21424,18,6643,0.465108759,0.809635816,0.461069829,1.482300193,0.631951671,DB0640310038683_,0.458942357,-0.211170742,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,133925,DB01306,10013700,53,4155,36,3830,0.16659974,1.357012182,0.869992431,2.138497383,0.306250378,DB0130610013700_,1.183352283,0.305285358,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,insulin aspart,DB01306
,133927,DB00820,10012575,54,11861,10,5806,0.003009428,2.643197339,1.331362027,5.826872335,0.013546962,DB0082010012575_,4.301592966,0.971989297,NA,10012575,Device breakage,10077536,Product issues,Prod,tadalafil,DB00820
,133935,DB00820,10074414,144,11771,32,5784,1.64774943135052e-05,2.211111932,1.496770738,3.357621431,0.000168296,DB0082010074414_,8.689783495,0.793495525,NA,10074414,Catheter management,10042613,Surgical and medical procedures,Surg,tadalafil,DB00820
,133938,DB00646,10005750,32,3421,23,1977,0.482229689,0.804081492,0.454586289,1.443357667,0.6466899,DB0064610005750_,0.435888389,-0.218054656,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,nystatin,DB00646
,133939,DB00927,10005750,76,7421,30,4986,0.012751689,1.702017661,1.100011122,2.69520638,0.043220909,DB0092710005750_,3.141430888,0.531814407,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,famotidine,DB00927
,133940,DB06724,10005750,82,7847,30,3889,0.189200279,1.354639459,0.880046791,2.136348594,0.33554614,DB0672410005750_,1.091995805,0.303535337,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,calcium carbonate,DB06724
,133949,DB00196,10013950,49,5034,36,3249,0.577639378,0.878492908,0.558370457,1.393968045,0.726593021,DB0019610013950_,0.319388765,-0.129547444,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,fluconazole,DB00196
,133962,DB00196,10030124,54,5029,36,3249,0.913752957,0.969064513,0.622462849,1.524791272,0.961391243,DB0019610030124_,0.039373832,-0.031424093,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,133965,DB00646,10047899,44,3409,24,1976,0.899450195,1.062671272,0.630022456,1.832978331,0.956490275,DB0064610047899_,0.044484657,0.060785806,NA,10047899,Weight increased,10022891,Investigations,Inv,nystatin,DB00646
,133966,DB06724,10047899,140,7789,41,3878,0.002407597,1.700014378,1.189865563,2.475954847,0.011319862,DB0672410047899_,4.481196419,0.530636709,NA,10047899,Weight increased,10022891,Investigations,Inv,calcium carbonate,DB06724
,133971,DB00115,10067482,58,18367,28,10444,0.502593579,1.177842198,0.73754899,1.922153801,0.663769487,DB0011510067482_,0.409820348,0.163684119,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,133977,DB00451,10011732,53,47218,18,15401,0.890475434,0.960381372,0.553333806,1.742667726,0.954651553,DB0045110011732_,0.046408871,-0.040424811,NA,10011732,Cyst,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,133995,DB00169,10014062,59,38632,20,18155,0.228395545,1.38637005,0.822372598,2.431611408,0.383908994,DB0016910014062_,0.95734975,0.326688857,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,133997,DB00451,10014062,77,47194,21,15398,0.557191362,1.196316967,0.730303513,2.042033992,0.710390946,DB0045110014062_,0.341939832,0.179247643,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,133998,DB00635,10014062,35,33018,19,23775,0.337833822,1.326422255,0.738028499,2.45525057,0.50694725,DB0063510014062_,0.679348325,0.282485284,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,134003,DB00399,10031282,56,6936,11,4987,1.54451150985148e-05,3.660016186,1.89484416,7.754662339,0.000158956,DB0039910031282_,8.746880103,1.29746757,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,134006,DB00972,10040753,151,2353,35,1144,4.90819945146028e-05,2.097186007,1.432868492,3.143876524,0.000434823,DB0097210040753_,7.740571208,0.740596449,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,azelastine,DB00972
,134009,DB00399,10044034,71,6921,66,4932,0.138226291,0.766625472,0.539393328,1.090865833,0.267280542,DB0039910044034_,1.319456452,-0.2657569,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,134010,DB00563,10044034,52,46594,13,15335,0.471952731,1.316459578,0.706624652,2.636263069,0.638049507,DB0056310044034_,0.449339402,0.274945995,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,134013,DB13961,10044034,40,9417,17,6397,0.106691551,1.5983141,0.884874845,3.009550137,0.221174921,DB1396110044034_,1.508801394,0.468949386,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,134027,DB00169,10044055,92,38599,14,18161,1.40378774284895e-05,3.091811175,1.75176088,5.877260678,0.000146422,DB0016910044055_,8.829018148,1.12875706,female,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,134028,DB00399,10044055,37,6955,17,4981,0.165938537,1.558677228,0.854851547,2.955515541,0.305365942,DB0039910044055_,1.186244412,0.44383753,NA,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,134029,DB00563,10044055,45,46601,12,15336,0.645089574,1.234083114,0.641821498,2.56383734,0.780833021,DB0056310044055_,0.247393954,0.210328277,NA,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,134052,DB00526,10037087,43,1555,28,1866,0.015512572,1.842509954,1.112807763,3.095239013,0.050604772,DB0052610037087_,2.983709401,0.611128747,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,oxaliplatin,DB00526
,134067,DB00695,10022687,71,27978,38,20490,0.121435428,1.368349162,0.909855059,2.08693724,0.243491511,DB0069510022687_,1.412673201,0.313605022,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,134089,DB08910,10028735,31,16713,23,17465,0.222696522,1.408450033,0.794645793,2.530745326,0.376835593,DB0891010028735_,0.975946281,0.342489832,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,134090,DB08910,10033371,266,16478,196,17292,0.00020752,1.424161756,1.178250966,1.723740766,0.001485676,DB0891010033371_,6.511885451,0.353583399,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,134113,DB06643,10039073,108,52313,12,7503,0.49001628,1.290821042,0.709034619,2.577003207,0.653360171,DB0664310039073_,0.425626739,0.255278482,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,134115,DB00829,10028391,39,8013,13,4441,0.14576783,1.662610494,0.867669903,3.398584892,0.278139263,DB0082910028391_,1.279633346,0.508388954,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diazepam,DB00829
,134116,DB00829,10028836,58,7994,13,4441,0.001757987,2.478415555,1.340304891,4.936362392,0.008744732,DB0082910028836_,4.739303845,0.907619467,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diazepam,DB00829
,134146,DB00254,10017944,40,5895,19,3369,0.587743631,1.20310118,0.67944981,2.203241446,0.734731949,DB0025410017944_,0.308249541,0.184902539,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,doxycycline,DB00254
,134147,DB00537,10017944,43,7514,23,4275,0.898077408,1.063666614,0.625917899,1.851761517,0.956338178,DB0053710017944_,0.044643686,0.061722009,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,ciprofloxacin,DB00537
,134148,DB01611,10017944,121,11792,23,2338,1,1.043078288,0.662191773,1.711585672,1,DB0161110017944_,0,0.042176234,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,134164,DB00215,10010144,832,10271,487,4789,0.000156191,0.796608315,0.707643487,0.897358337,0.001167836,DB0021510010144_,6.752602923,-0.227392171,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,134174,DB00588,10020751,226,16298,71,8397,0.000205556,1.639955091,1.24911647,2.175440566,0.001474022,DB0058810020751_,6.519760482,0.494668858,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,fluticasone propionate,DB00588
,134182,DB11750,10013709,135,2365,102,1411,0.084279757,0.789700792,0.600763473,1.040542902,0.185535461,DB1175010013709_,1.684509253,-0.236101149,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,clobetasol,DB11750
,134186,DB11750,10015150,32,2468,22,1491,0.672540943,0.878770881,0.492882299,1.593751153,0.801166493,DB1175010015150_,0.221686497,-0.129231074,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,clobetasol,DB11750
,134202,DB00285,10007617,220,10731,86,3632,0.259465493,0.865852544,0.669814076,1.127574687,0.420601325,DB0028510007617_,0.866069866,-0.144040657,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,venlafaxine,DB00285
,134228,DB00275,10011906,47,2013,36,1201,0.301367446,0.778997607,0.490776397,1.245511918,0.46764856,DB0027510011906_,0.760038205,-0.249747305,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,olmesartan,DB00275
,134229,DB00364,10011906,118,2632,74,1326,0.159506303,0.803417168,0.590992116,1.097874073,0.296795346,DB0036410011906_,1.214712448,-0.218881188,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sucralfate,DB00364
,134231,DB00524,10035598,40,1537,21,1323,0.070051702,1.639284294,0.938342328,2.942225353,0.161342751,DB0052410035598_,1.824224288,0.494259741,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metolazone,DB00524
,134232,DB01069,10035598,47,6653,23,2372,0.220888165,0.728590416,0.432565398,1.260019774,0.37455941,DB0106910035598_,0.982004851,-0.316643549,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,promethazine,DB01069
,134254,DB00863,10022004,77,10596,24,5816,0.015923973,1.760954787,1.099850206,2.9158565,0.051648769,DB0086310022004_,2.96328892,0.565856155,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,134256,DB00555,10027599,84,6963,13,3473,1.1286715265302e-05,3.222601875,1.783008253,6.311267502,0.000120525,DB0055510027599_,9.02365665,1.170189069,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,134257,DB00863,10027599,119,10554,18,5822,4.9622842893824e-09,3.646724019,2.208148069,6.370548473,1.19226364302026e-07,DB0086310027599_,15.94224193,1.293829236,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,134258,DB00399,10047571,39,6953,20,4978,0.236545737,1.396063646,0.793569839,2.529759721,0.393815716,DB0039910047571_,0.931872204,0.333656595,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,zoledronic acid,DB00399
,134259,DB00863,10047571,79,10594,20,5820,0.001428637,2.169911245,1.313655564,3.746665574,0.007384078,DB0086310047571_,4.908429281,0.774686266,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,ranitidine,DB00863
,134260,DB00169,10057372,58,38633,9,18166,0.000881343,3.030252835,1.490667184,6.958868036,0.004965409,DB0016910057372_,5.305259696,1.10864606,female,10057372,Paraesthesia oral,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,134276,DB00737,10012735,207,2594,49,883,0.024845225,1.437951899,1.0379057,2.024642517,0.073155229,DB0073710012735_,2.615171674,0.363219809,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,meclizine,DB00737
,134277,DB01036,10012735,70,1431,20,402,0.897024961,0.983236574,0.582711579,1.728197482,0.956338178,DB0103610012735_,0.044643686,-0.016905523,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,tolterodine,DB01036
,134278,DB01036,10019211,66,1435,7,415,0.00875153,2.725785217,1.238626961,7.097448392,0.032009179,DB0103610019211_,3.441732562,1.00275654,female,10019211,Headache,10029205,Nervous system disorders,Nerv,tolterodine,DB01036
,134283,DB00737,10028411,54,2747,9,923,0.055320391,2.015797054,0.981997353,4.662528111,0.134887912,DB0073710028411_,2.003311129,0.701014677,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,meclizine,DB00737
,134285,DB00698,10037087,55,3093,7,422,1,1.071995738,0.482619976,2.808815144,1,DB0069810037087_,0,0.069522087,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,nitrofurantoin,DB00698
,134287,DB00169,10039101,239,38452,89,18086,0.065492585,1.263041582,0.985556178,1.6309738,0.15329913,DB0016910039101_,1.875364166,0.233522766,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,134299,DB00169,10058046,38,38653,15,18160,0.659303218,1.190195287,0.639446463,2.32972808,0.791856756,DB0016910058046_,0.233374768,0.1741174,NA,10058046,Post procedural complication,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,134303,DB01222,10001760,99,9175,18,5387,3.66445044562443e-07,3.22904676,1.938573642,5.678389671,5.84289232412728e-06,DB0122210001760_,12.05028462,1.172186973,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,budesonide,DB01222
,134313,DB08906,10040753,52,2141,10,1148,0.001715533,2.787527122,1.394762233,6.175755029,0.008572029,DB0890610040753_,4.759250781,1.025154867,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,fluticasone furoate,DB08906
,134317,DB00451,10003997,48,47223,22,15397,0.210326969,0.711383513,0.421043511,1.237945923,0.361605699,DB0045110003997_,1.017200889,-0.340543595,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,134347,DB00181,10031252,27,9829,34,5837,0.004888546,0.471606465,0.273382739,0.806195376,0.020099395,DB0018110031252_,3.907065548,-0.751610401,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,baclofen,DB00181
,134349,DB00193,10031252,35,19285,30,8672,0.01056359,0.524610998,0.312700897,0.885242733,0.037184523,DB0019310031252_,3.29186264,-0.645098248,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,tramadol,DB00193
,134364,DB00564,10046571,45,2559,13,1450,0.037728366,1.961112141,1.035435266,3.97610681,0.101069109,DB0056410046571_,2.291950745,0.673511731,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,carbamazepine,DB00564
,134365,DB00654,10046571,59,3757,19,2579,0.003489954,2.131374734,1.24914842,3.795435693,0.015292909,DB0065410046571_,4.180366023,0.756767187,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,latanoprost,DB00654
,134369,DB00402,10070863,57,1295,23,673,0.337681413,1.287801011,0.772991066,2.210545111,0.506838187,DB0040210070863_,0.679563485,0.252936121,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,eszopiclone,DB00402
,134392,DB00404,10029223,46,19846,15,9847,0.174439913,1.52156959,0.833757883,2.935653015,0.316687027,DB0040410029223_,1.149841288,0.419742427,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,134393,DB00497,10029223,57,19210,28,16347,0.016455733,1.732286883,1.083109627,2.830100716,0.052974762,DB0049710029223_,2.937939669,0.549442433,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,134404,DB01098,10038428,32,8117,29,7180,1,0.976065643,0.571264696,1.674133217,1,DB0109810038428_,0,-0.024225438,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,rosuvastatin,DB01098
,134405,DB01104,10038428,37,15426,20,7266,0.670050473,0.871405991,0.492423417,1.58567329,0.799758272,DB0110410038428_,0.223445757,-0.137647291,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,sertraline,DB01104
,134427,DB00404,10060933,66,19826,23,9839,0.175469788,1.42405611,0.873529372,2.400557677,0.317952805,DB0040410060933_,1.14585232,0.353509216,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,134428,DB00497,10060933,48,19219,36,16339,0.585721317,1.133513994,0.720159889,1.798603246,0.733075487,DB0049710060933_,0.310506599,0.125322537,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,134432,DB01098,10060933,36,8113,19,7190,0.077924973,1.679115657,0.936976858,3.102029419,0.17485555,DB0109810060933_,1.743795074,0.51826726,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,134445,DB00295,10061623,56,14607,65,9537,0.001976164,0.562535874,0.385967794,0.817557528,0.009634867,DB0029510061623_,4.642366772,-0.575300371,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,134449,DB01098,10061623,40,8109,42,7167,0.440043783,0.841756674,0.531378108,1.331604879,0.608354756,DB0109810061623_,0.496997087,-0.172264292,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,134450,DB01224,10061623,38,8070,39,5878,0.134251003,0.709728978,0.441252793,1.140634657,0.261653329,DB0122410061623_,1.340734822,-0.342872103,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,134459,DB00285,10023232,49,10902,13,3705,0.468506648,1.280925291,0.683382483,2.576847044,0.634974592,DB0028510023232_,0.454170293,0.2475827,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,venlafaxine,DB00285
,134460,DB00264,10059570,50,29557,37,24855,0.591260157,1.136359104,0.727879043,1.788620938,0.737656337,DB0026410059570_,0.304277231,0.127829383,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,metoprolol,DB00264
,134464,DB01050,10017412,44,18064,14,9357,0.127160439,1.627946774,0.875063032,3.218290846,0.251668711,DB0105010017412_,1.379641695,0.487319573,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,ibuprofen,DB01050
,134465,DB00982,10012374,48,3316,55,2046,0.002057454,0.538564218,0.356388769,0.81135742,0.009953101,DB0098210012374_,4.609871077,-0.618848535,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,isotretinoin,DB00982
,134466,DB00982,10016256,62,3302,49,2052,0.236799621,0.786360662,0.529590834,1.173134256,0.394103778,DB0098210016256_,0.931141007,-0.240339734,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,isotretinoin,DB00982
,134474,DB00635,10048983,49,33004,47,23747,0.178186663,0.750149674,0.492166998,1.144386323,0.321566398,DB0063510048983_,1.13455123,-0.287482527,NA,10048983,Cytomegalovirus colitis,10021881,Infections and infestations,Infec,prednisone,DB00635
,134481,DB00196,10000059,52,5031,17,3268,0.012946185,1.986774435,1.128094428,3.671543388,0.043730703,DB0019610000059_,3.129704827,0.686512437,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,fluconazole,DB00196
,134482,DB00254,10000059,120,5815,29,3359,9.56899204569098e-06,2.39005453,1.578299697,3.728517631,0.00010467,DB0025410000059_,9.164702205,0.871316182,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,doxycycline,DB00254
,134483,DB00285,10000059,122,10829,32,3686,0.225650572,1.297671121,0.871314641,1.983742757,0.380462829,DB0028510000059_,0.966366796,0.260571212,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,134484,DB00422,10000059,40,3395,27,2922,0.388805599,1.275028141,0.761213777,2.166266782,0.558685537,DB0042210000059_,0.582168511,0.24296825,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,methylphenidate,DB00422
,134486,DB08910,10000059,80,16664,59,17429,0.04165703,1.418157355,0.999769196,2.021653467,0.109026689,DB0891010000059_,2.216162577,0.349358392,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,134487,DB00207,10007515,44,9036,70,5385,2.67967972505352e-07,0.374622062,0.250523301,0.554913584,4.41048100018984e-06,DB0020710007515_,12.3315268,-0.981837596,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,azithromycin,DB00207
,134488,DB00254,10007515,36,5899,20,3368,1,1.027697765,0.578155911,1.876891341,1,DB0025410007515_,0,0.027321121,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,doxycycline,DB00254
,134489,DB00281,10007515,169,11289,113,5558,0.015165314,0.736314317,0.575520365,0.944973565,0.049746698,DB0028110007515_,3.000811199,-0.306098191,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,lidocaine,DB00281
,134491,DB00787,10007515,45,16955,56,17192,0.320297752,0.814810108,0.537510369,1.228992009,0.488511072,DB0078710007515_,0.716393142,-0.20480019,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,acyclovir,DB00787
,134492,DB08910,10007515,30,16714,29,17459,0.795438038,1.080566021,0.626393395,1.866704969,0.889265654,DB0891010007515_,0.117359265,0.077484998,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,pomalidomide,DB08910
,134493,DB00422,10010774,51,3384,29,2920,0.089931672,1.517385093,0.940861993,2.489737872,0.195101849,DB0042210010774_,1.634233555,0.41698852,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,methylphenidate,DB00422
,134495,DB00186,10012601,37,16864,26,9982,0.515735684,0.842348342,0.496177665,1.449698533,0.67545354,DB0018610012601_,0.392370903,-0.171561642,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,lorazepam,DB00186
,134500,DB00656,10012601,40,11973,15,6604,0.258584961,1.47083618,0.794245837,2.868519254,0.419639791,DB0065610012601_,0.868358576,0.385831069,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,trazodone,DB00656
,134502,DB00787,10012601,34,16966,69,17179,0.000737983,0.498952331,0.32058749,0.763327847,0.004274248,DB0078710012601_,5.45514713,-0.695244717,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,acyclovir,DB00787
,134503,DB00996,10012601,140,38813,89,22336,0.491843396,0.905248735,0.688705255,1.195083175,0.654902544,DB0099610012601_,0.423268842,-0.099545527,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,134508,DB00476,10015090,46,17211,10,6167,0.172434351,1.648311084,0.819787512,3.665381819,0.314054664,DB0047610015090_,1.158188219,0.499751178,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,134510,DB00813,10015090,31,10541,26,10142,0.691054789,1.147167952,0.658640672,2.013077196,0.813688495,DB0081310015090_,0.20617767,0.137296255,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,134511,DB08910,10015090,50,16694,53,17435,1,0.985269905,0.655476786,1.479104591,1,DB0891010015090_,0,-0.014839661,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,134528,DB00196,10020751,49,5034,20,3265,0.083900873,1.588960239,0.925233927,2.827518831,0.184910448,DB0019610020751_,1.687883636,0.463079864,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,fluconazole,DB00196
,134529,DB00281,10020751,97,11361,40,5631,0.362531257,1.201899612,0.822307742,1.786017367,0.53220405,DB0028110020751_,0.63072831,0.183903315,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,lidocaine,DB00281
,134530,DB00285,10020751,90,10861,14,3704,0.004405108,2.192398168,1.239273082,4.175775558,0.018465555,DB0028510020751_,3.991848149,0.784995998,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,venlafaxine,DB00285
,134531,DB00656,10020751,99,11914,27,6592,0.000721796,2.028691743,1.312697508,3.234013482,0.004200689,DB0065610020751_,5.47250674,0.707391124,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,trazodone,DB00656
,134533,DB00813,10020751,59,10513,41,10127,0.109827728,1.386162109,0.914038074,2.120106638,0.225815575,DB0081310020751_,1.488036652,0.326538856,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,fentanyl,DB00813
,134534,DB08910,10020751,111,16633,79,17409,0.008774932,1.470589926,1.091238606,1.989691575,0.032067999,DB0891010020751_,3.439896672,0.38566363,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,pomalidomide,DB08910
,134535,DB00196,10027175,53,5030,8,3277,9.27320856364876e-06,4.315541861,2.035026937,10.52523519,0.000101669,DB0019610027175_,9.193791774,1.462222893,female,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,fluconazole,DB00196
,134536,DB00207,10027175,73,9007,23,5432,0.005749552,1.914063867,1.182187263,3.209528635,0.022887217,DB0020710027175_,3.777176721,0.649228661,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,134537,DB00254,10027175,50,5885,9,3379,0.000559906,3.18951719,1.55035529,7.387173332,0.00338909,DB0025410027175_,5.687193735,1.159869554,female,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,doxycycline,DB00254
,134538,DB00281,10027175,72,11386,27,5644,0.239459581,1.321874217,0.837611782,2.142963374,0.397298097,DB0028110027175_,0.923068407,0.279050591,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,134539,DB00422,10027175,65,3370,16,2933,8.21513219494469e-07,3.534944347,2.016670148,6.560088715,1.20499302312568e-05,DB0042210027175_,11.32645169,1.262697556,female,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,methylphenidate,DB00422
,134541,DB11089,10027175,110,10065,67,8340,0.048662614,1.360386729,0.993556148,1.874510454,0.122559938,DB1108910027175_,2.099155076,0.307769019,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,docusate,DB11089
,134543,DB00656,10029331,86,11927,55,6564,0.378830079,0.860557544,0.605581567,1.231795579,0.548800061,DB0065610029331_,0.600021092,-0.150174793,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,134558,DB00207,10038435,79,9001,74,5381,0.007034198,0.638262432,0.458004298,0.890232244,0.026895614,DB0020710038435_,3.615792059,-0.449005745,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,azithromycin,DB00207
,134559,DB00254,10038435,50,5885,37,3351,0.262555488,0.76951779,0.491952406,1.213481887,0.424341071,DB0025410038435_,0.857217734,-0.261991207,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,doxycycline,DB00254
,134561,DB00656,10038435,57,11956,44,6575,0.095709389,0.712454526,0.471753591,1.082233949,0.204347436,DB0065610038435_,1.587933615,-0.339039192,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,trazodone,DB00656
,134563,DB00196,10043607,42,5041,31,3254,0.630447156,0.874574852,0.535645405,1.442178577,0.769328241,DB0019610043607_,0.26223756,-0.134017395,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,fluconazole,DB00196
,134566,DB11089,10043607,95,10080,99,8308,0.110721727,0.790919208,0.589584612,1.060486857,0.227167538,DB1108910043607_,1.482067483,-0.234559455,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,docusate,DB11089
,134568,DB00787,10047899,266,16734,182,17066,3.36988952741724e-05,1.490509163,1.228246358,1.812101273,0.000314272,DB0078710047899_,8.065251897,0.399117782,NA,10047899,Weight increased,10022891,Investigations,Inv,acyclovir,DB00787
,134569,DB08910,10047899,138,16606,111,17377,0.041703698,1.300951216,1.004977103,1.687266511,0.109135875,DB0891010047899_,2.215161615,0.263095701,NA,10047899,Weight increased,10022891,Investigations,Inv,pomalidomide,DB08910
,134570,DB00207,10068319,81,8999,19,5436,7.06907543916616e-05,2.575083547,1.545777486,4.500891575,0.000591654,DB0020710068319_,7.432589365,0.945881979,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,134571,DB00254,10068319,44,5891,8,3380,0.001259008,3.155341627,1.467084205,7.771106207,0.006646522,DB0025410068319_,5.01366159,1.149096771,female,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxycycline,DB00254
,134572,DB00281,10068319,63,11395,18,5653,0.043490187,1.736281122,1.013914578,3.119171491,0.112613494,DB0028110068319_,2.183793731,0.55174554,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,134573,DB00476,10068319,110,17147,12,6165,7.31501412519202e-06,3.295817945,1.811106146,6.576230119,8.24507488339074e-05,DB0047610068319_,9.403309427,1.192654375,female,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,134576,DB11089,10068319,73,10102,27,8380,0.000248238,2.242684358,1.422932391,3.632235434,0.001724578,DB1108910068319_,6.362772963,0.807673523,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,134598,DB00624,10053762,45,517,112,4284,1.32121125941161e-09,3.328386196,2.272628203,4.807165043,3.58390484557627e-08,DB0062410053762_,17.1442278,1.202487561,female,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,testosterone,DB00624
,134612,DB01229,10061309,47,5694,15,2694,0.219073484,1.482408823,0.812678025,2.859636043,0.37238313,DB0122910061309_,0.987832037,0.393668348,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,paclitaxel,DB01229
,134659,DB01050,10041466,41,18067,16,9355,0.401922789,1.326861988,0.72811702,2.534477201,0.57167427,DB0105010041466_,0.559185908,0.282816747,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,134673,DB00471,10013911,46,14143,25,5440,0.183877821,0.707755806,0.42538743,1.203348649,0.328779874,DB0047110013911_,1.112366829,-0.345656151,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,134676,DB00471,10056819,53,14136,12,5453,0.097342327,1.703745988,0.89798815,3.505618489,0.206884127,DB0047110056819_,1.575596417,0.532829349,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,134677,DB05676,10016322,331,46798,189,25140,0.518270182,0.940816358,0.783935906,1.13171445,0.677563071,DB0567610016322_,0.389252637,-0.061007315,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,134682,DB14513,10011224,165,7012,79,3485,0.836643423,1.038046601,0.7865803,1.37944821,0.915625842,DB1451310011224_,0.088147467,0.037340678,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium,DB14513
,134686,DB14513,10030095,35,7142,16,3548,0.88192236,1.086694895,0.584905062,2.105756629,0.950599903,DB1451310030095_,0.050662017,0.083140883,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,134696,DB08907,10020751,35,4218,19,3891,0.074871194,1.699181887,0.943887985,3.150202259,0.169632318,DB0890710020751_,1.774122022,0.530146892,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,canagliflozin,DB08907
,134697,DB08907,10046735,35,4218,28,3882,0.614281685,1.150406457,0.678495401,1.967180106,0.755840897,DB0890710046735_,0.279924379,0.140115321,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,canagliflozin,DB08907
,134704,DB00641,10013754,32,14092,21,12454,0.335429888,1.346670166,0.752507573,2.458618192,0.504645876,DB0064110013754_,0.683898332,0.297635002,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,134705,DB01050,10013754,60,18048,33,9338,0.826655396,0.940726616,0.604784961,1.486531999,0.908584167,DB0105010013754_,0.095867751,-0.061102706,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,134706,DB00395,10016322,50,2134,10,726,0.134854968,1.700842315,0.846831489,3.781278652,0.262441256,DB0039510016322_,1.337728008,0.531123608,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,carisoprodol,DB00395
,134736,DB06403,10000060,278,21193,80,6581,0.573959303,1.079078332,0.837274267,1.403892194,0.723799759,DB0640310000060_,0.323240501,0.07610728,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,134737,DB00374,10038435,184,17532,80,5644,0.03038584,0.740439298,0.565456064,0.976891956,0.085517619,DB0037410038435_,2.459032848,-0.300511623,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,treprostinil,DB00374
,134738,DB08931,10038435,96,6481,43,2403,0.335999612,0.827826652,0.57008093,1.21928964,0.505133253,DB0893110038435_,0.682933018,-0.188951504,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,riociguat,DB08931
,134739,DB08931,10061105,45,6532,33,2413,0.004461234,0.50376544,0.313584618,0.817035108,0.018647299,DB0893110061105_,3.982053948,-0.685644515,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,riociguat,DB08931
,134750,DB00973,10060795,37,3814,21,3000,0.287828183,1.385805603,0.788340824,2.497322354,0.452837959,DB0097310060795_,0.792220924,0.326281634,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,ezetimibe,DB00973
,134753,DB00177,10023232,46,4754,14,2836,0.031048188,1.959936273,1.056403595,3.867728224,0.087018352,DB0017710023232_,2.441636237,0.672911959,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,valsartan,DB00177
,134755,DB01222,10023232,76,9198,20,5385,0.000915809,2.224612924,1.343277426,3.8496109,0.005125528,DB0122210023232_,5.273521733,0.799582934,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,budesonide,DB01222
,134756,DB01129,10028813,67,845,25,411,0.300046036,1.303297806,0.798435597,2.187420982,0.466131391,DB0112910028813_,0.76328773,0.264897826,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,rabeprazole,DB01129
,134762,DB00654,10015150,37,3779,15,2583,0.090236018,1.685869513,0.900972983,3.313838341,0.195616803,DB0065410015150_,1.631597619,0.522281462,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,latanoprost,DB00654
,134763,DB00678,10015150,126,15473,63,10661,0.037674062,1.377996135,1.009416691,1.897510762,0.100959649,DB0067810015150_,2.293034356,0.320630368,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,134781,DB04868,10028596,37,1604,47,1469,0.150894353,0.721056008,0.452866329,1.140543474,0.285176921,DB0486810028596_,1.254645518,-0.327038463,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,nilotinib,DB04868
,134784,DB06403,10074414,84,21387,30,6631,0.508192481,0.868162285,0.565467366,1.366105175,0.66876728,DB0640310074414_,0.402319143,-0.141376617,NA,10074414,Catheter management,10042613,Surgical and medical procedures,Surg,ambrisentan,DB06403
,134787,DB00115,10021114,41,18384,10,10462,0.01285481,2.333172882,1.148728706,5.225714493,0.043486318,DB0011510021114_,3.135308914,0.847229093,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,cyanocobalamin,DB00115
,134788,DB00186,10021114,36,16865,14,9994,0.190727533,1.523775256,0.801583503,3.059921155,0.337469167,DB0018610021114_,1.086281129,0.421190977,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,lorazepam,DB00186
,134793,DB00715,10028334,89,4754,22,2265,0.005391491,1.927264556,1.194054225,3.237590155,0.021718825,DB0071510028334_,3.829575865,0.656101669,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,paroxetine,DB00715
,134794,DB06637,10028334,103,6059,30,1989,0.613240694,1.127049577,0.741540074,1.759585733,0.754989772,DB0663710028334_,0.281051077,0.119603225,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,dalfampridine,DB06637
,134795,DB00715,10028411,61,4782,15,2272,0.019007021,1.931978439,1.081973205,3.668441278,0.059380702,DB0071510028411_,2.823785981,0.658544576,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,paroxetine,DB00715
,134800,DB06637,10052238,107,6055,9,2010,3.5465881129218e-06,3.946274589,1.997709098,8.880711698,4.37662293653285e-05,DB0663710052238_,10.03664806,1.372771992,female,10052238,Escherichia urinary tract infection,10021881,Infections and infestations,Infec,dalfampridine,DB06637
,134813,DB00381,10019744,12,29348,39,22848,2.92628038902518e-06,0.239550781,0.114159873,0.467128873,3.70775030250793e-05,DB0038110019744_,10.20250016,-1.428989854,male,10019744,Hepatitis C,10021881,Infections and infestations,Infec,amlodipine,DB00381
,134830,DB01068,10049119,46,13717,21,6819,0.796278624,1.088923515,0.636199587,1.922667861,0.889699623,DB0106810049119_,0.116871375,0.085189607,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,134843,DB01050,10061284,41,18067,24,9347,0.694522025,0.883818691,0.521150449,1.530177396,0.816125866,DB0105010061284_,0.203186689,-0.123503338,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,134861,DB00186,10022095,65,16836,11,9997,2.17895478439747e-05,3.508603631,1.836208037,7.376732019,0.000214873,DB0018610022095_,8.445465609,1.255218132,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,134865,DB00181,10037153,50,9806,10,5861,0.000698788,2.988292954,1.496277099,6.613499379,0.004084878,DB0018110037153_,5.500463471,1.094702306,female,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,baclofen,DB00181
,134866,DB00186,10037153,86,16815,21,9987,0.000118155,2.432226144,1.494553755,4.130455187,0.000919934,DB0018610037153_,6.991208576,0.888806947,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,134867,DB00230,10037153,108,19566,39,8612,0.323624477,1.218854806,0.837123608,1.807695629,0.492058967,DB0023010037153_,0.709156719,0.197911734,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,134868,DB00295,10037153,35,14628,20,9582,0.680395231,1.146357904,0.643269168,2.096989166,0.806629621,DB0029510037153_,0.214890673,0.136589876,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,morphine,DB00295
,134869,DB00497,10037153,69,19198,37,16338,0.02452947,1.587024391,1.048963834,2.435727114,0.072448691,DB0049710037153_,2.624876681,0.46186081,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,134870,DB01069,10037153,38,6662,12,2383,0.872107308,1.13270062,0.578233953,2.385098459,0.943852291,DB0106910037153_,0.057785596,0.12460471,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,promethazine,DB01069
,134905,DB08908,10016334,73,10600,21,3258,0.902906954,1.068419931,0.648956762,1.831075946,0.957326661,DB0890810016334_,0.043610607,0.066180857,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,134908,DB00973,10020751,43,3808,17,3004,0.017973358,1.99515516,1.111861767,3.739123434,0.056796873,DB0097310020751_,2.868274011,0.690721822,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ezetimibe,DB00973
,134911,DB00394,10033371,62,1577,6,788,4.80426517964155e-06,5.161679696,2.227875114,14.66835514,5.70886574352976e-05,DB0039410033371_,9.770905105,1.641262049,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,beclomethasone dipropionate,DB00394
,134914,DB00820,10015958,40,11875,15,5801,0.472208847,1.302710098,0.70337625,2.540861493,0.638264446,DB0082010015958_,0.449002589,0.264446785,NA,10015958,Eye pain,10015919,Eye disorders,Eye,tadalafil,DB00820
,134924,DB00169,10017888,44,38647,16,18159,0.409621227,1.292088498,0.714579444,2.453817737,0.579052058,DB0016910017888_,0.546362895,0.2562599,NA,10017888,Gastroenteritis,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,134944,DB00115,10031009,77,18348,21,10451,0.00210958,2.088479504,1.274513039,3.565699314,0.010164114,DB0011510031009_,4.588892044,0.736436291,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,134946,DB00341,10031009,36,11369,14,5054,0.760030158,1.143093521,0.601053527,2.296279325,0.866547788,DB0034110031009_,0.143238021,0.133738202,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,134948,DB00588,10031009,52,16472,15,8453,0.05205382,1.778965377,0.985584921,3.404366109,0.128902412,DB0058810031009_,2.04869966,0.576031947,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,134951,DB00341,10041232,45,11360,10,5058,0.055729622,2.003536575,0.99440827,4.462299431,0.135590606,DB0034110041232_,1.998115183,0.694913907,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,134952,DB00451,10041232,79,47192,16,15403,0.094231532,1.61148932,0.933213557,2.956722269,0.202134589,DB0045110041232_,1.598821519,0.477158795,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,134954,DB00588,10041232,44,16480,12,8456,0.048689849,1.881348653,0.976108665,3.915429948,0.122586939,DB0058810041232_,2.098934794,0.631988888,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,134971,DB00115,10068319,142,18283,27,10445,7.04646173338568e-09,3.00448923,1.978841234,4.721676876,1.636908940893e-07,DB0011510068319_,15.62528598,1.10010758,female,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,134977,DB01050,10027599,198,17910,38,9333,7.52512429607959e-10,2.715146906,1.909169767,3.954072291,2.13951208353112e-08,DB0105010027599_,17.66010294,0.998846061,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,135002,DB00497,10005750,120,19147,91,16284,0.446146897,1.121478355,0.846205566,1.490615897,0.614009696,DB0049710005750_,0.48774456,0.114647775,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,oxycodone,DB00497
,135010,DB00425,10008469,85,12610,22,7462,0.000273339,2.28623039,1.415596331,3.842375476,0.0018698,DB0042510008469_,6.281924015,0.826904343,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,135011,DB00497,10008469,83,19184,54,16321,0.144031031,1.307639646,0.91658754,1.879017023,0.275585489,DB0049710008469_,1.288857394,0.268223715,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,135012,DB00531,10008469,36,7216,16,6500,0.017760432,2.02658924,1.09509553,3.915031411,0.056305989,DB0053110008469_,2.876954368,0.706354202,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,135016,DB00927,10008469,110,7387,47,4969,0.008694421,1.574273832,1.106829505,2.269547788,0.031842393,DB0092710008469_,3.446956776,0.453794107,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,135017,DB00959,10008469,116,7962,51,4951,0.044823387,1.414319261,1.007017212,2.010475096,0.11524388,DB0095910008469_,2.160704697,0.346648328,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,135019,DB01175,10008469,67,10657,18,4874,0.045963191,1.702313686,0.998429632,3.047992895,0.117417517,DB0117510008469_,2.142019171,0.531988318,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,135027,DB01175,10008531,91,10633,34,4858,0.334782214,1.222788098,0.814974634,1.873527776,0.503951579,DB0117510008531_,0.68527509,0.201133578,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,135030,DB00184,10011224,34,1260,17,965,0.197674631,1.531467601,0.826391253,2.941679629,0.346172602,DB0018410011224_,1.060817779,0.426226492,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nicotine,DB00184
,135031,DB00327,10011224,71,6067,44,4218,0.56889316,1.121878995,0.75788365,1.676814355,0.719897778,DB0032710011224_,0.328646052,0.115004953,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydromorphone,DB00327
,135032,DB00683,10011224,26,1558,30,1608,0.68865193,0.89451136,0.505638185,1.572790133,0.812314761,DB0068310011224_,0.207867378,-0.111477677,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,midazolam,DB00683
,135033,DB00813,10011224,93,10479,78,10090,0.398431921,1.14803866,0.839423969,1.573665501,0.568240687,DB0081310011224_,0.565210206,0.138054973,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,135037,DB00184,10012735,42,1252,23,959,0.206991286,1.398533584,0.815628192,2.45410024,0.357603993,DB0018410012735_,1.02832907,0.335424247,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,nicotine,DB00184
,135038,DB06723,10013968,56,974,23,587,0.151980996,1.4670426,0.877337993,2.526333859,0.286726753,DB0672310013968_,1.249225595,0.383248537,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,aluminum hydroxide,DB06723
,135040,DB00295,10019303,43,14620,28,9574,1,1.005672112,0.610121686,1.682346683,1,DB0029510019303_,0,0.005656086,NA,10019303,Heart rate increased,10022891,Investigations,Inv,morphine,DB00295
,135045,DB00927,10019303,63,7434,29,4987,0.108859168,1.457292091,0.923221558,2.350497715,0.224323878,DB0092710019303_,1.494664388,0.376579981,NA,10019303,Heart rate increased,10022891,Investigations,Inv,famotidine,DB00927
,135046,DB00959,10019303,62,8016,22,4980,0.023980155,1.750745191,1.059610875,2.995253079,0.07119828,DB0095910019303_,2.642286613,0.560041521,NA,10019303,Heart rate increased,10022891,Investigations,Inv,methylprednisolone,DB00959
,135048,DB01175,10019303,54,10670,13,4879,0.034795731,1.899333441,1.021756003,3.797813883,0.09503612,DB0117510019303_,2.353498247,0.641503004,NA,10019303,Heart rate increased,10022891,Investigations,Inv,escitalopram,DB01175
,135053,DB00959,10021143,73,8005,80,4922,0.000415208,0.561113093,0.402037379,0.782042373,0.002642232,DB0095910021143_,5.936131318,-0.577832802,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,135055,DB00184,10028813,64,1230,41,941,0.420335012,1.194117262,0.786518855,1.830485887,0.589285071,DB0018410028813_,0.528845221,0.177407219,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,nicotine,DB00184
,135060,DB00683,10033318,30,1554,24,1614,0.410472492,1.29815317,0.730018196,2.331507327,0.579850028,DB0068310033318_,0.544985782,0.260942616,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,midazolam,DB00683
,135061,DB00813,10033318,56,10516,52,10116,0.923191574,1.035966541,0.696715106,1.542732443,0.966449231,DB0081310033318_,0.03412651,0.035334847,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,fentanyl,DB00813
,135062,DB00959,10033318,44,8034,30,4972,0.719441395,0.907684054,0.557085631,1.497446062,0.834385681,DB0095910033318_,0.181059536,-0.096858919,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,methylprednisolone,DB00959
,135068,DB00425,10036790,42,12653,20,7464,0.51070098,1.238810247,0.710619568,2.229088472,0.671102715,DB0042510036790_,0.398833076,0.214151441,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,135073,DB00927,10036790,42,7455,21,4995,0.303969393,1.340009248,0.774825231,2.385075468,0.470557761,DB0092710036790_,0.753836562,0.292676515,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,135074,DB00959,10036790,39,8039,14,4988,0.08885941,1.728397812,0.916947485,3.449776958,0.193350131,DB0095910036790_,1.643252582,0.547194859,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,135076,DB01075,10036790,58,19890,36,11061,0.592008386,0.895958903,0.580746533,1.399097964,0.738272585,DB0107510036790_,0.303442166,-0.109860734,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,135081,DB00295,10037423,60,14603,77,9525,0.000100829,0.508261619,0.356102618,0.72246861,0.000803609,DB0029510037423_,7.126398048,-0.676758966,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,135082,DB00327,10037423,39,6099,16,4246,0.075197321,1.696853001,0.925232712,3.257024755,0.170180515,DB0032710037423_,1.770895555,0.52877536,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydromorphone,DB00327
,135083,DB00433,10037423,31,7625,34,5986,0.210197316,0.715805887,0.42490716,1.201770977,0.361408761,DB0043310037423_,1.017745658,-0.334346256,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prochlorperazine,DB00433
,135085,DB00959,10037423,52,8026,27,4975,0.487910599,1.193749374,0.735092402,1.979688401,0.65156379,DB0095910037423_,0.428379974,0.177099088,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,135098,DB00186,10043089,32,16869,19,9989,1,0.997307349,0.548039456,1.863280655,1,DB0018610043089_,0,-0.002696283,NA,10043089,Tachypnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,135110,DB00904,10043089,26,23043,46,14410,1.54946970156879e-05,0.3534695,0.209647935,0.584251271,0.000159349,DB0090410043089_,8.744412785,-1.039958079,male,10043089,Tachypnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,135118,DB00184,10047700,41,1253,23,959,0.25184951,1.364159831,0.793353726,2.398742645,0.411910373,DB0018410047700_,0.886949495,0.31053873,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,nicotine,DB00184
,135119,DB00624,10047700,9,553,56,4340,0.551988574,1.261236701,0.54535617,2.587747683,0.705828939,DB0062410047700_,0.348382367,0.232092749,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,testosterone,DB00624
,135120,DB00563,10062544,43,46603,8,15340,0.146480055,1.76916189,0.822012271,4.357986255,0.279012155,DB0056310062544_,1.276499931,0.570505926,NA,10062544,Tooth fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,135123,DB00115,10017944,91,18334,50,10422,0.930055055,1.034583264,0.724195398,1.492927829,0.971371126,DB0011510017944_,0.029046674,0.033998702,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,135124,DB00281,10017944,42,11416,10,5661,0.037906962,2.082630877,1.027327806,4.658774335,0.101464816,DB0028110017944_,2.288043181,0.733631939,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,135131,DB00115,10019974,125,18300,44,10428,0.006180023,1.618826706,1.138596833,2.339608548,0.024232401,DB0011510019974_,3.72006465,0.481701631,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,135132,DB00158,10019974,147,16668,29,8075,2.17501419732404e-06,2.455643105,1.638699605,3.79836664,2.85351875101884e-05,DB0015810019974_,10.46437258,0.898388684,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,folic acid,DB00158
,135133,DB00169,10019974,219,38472,69,18106,0.003489995,1.493722474,1.134037021,1.988653551,0.015292909,DB0016910019974_,4.180366023,0.401271309,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,135134,DB00193,10019974,133,19187,33,8669,0.001358527,1.820922249,1.234753382,2.755425835,0.007087911,DB0019310019974_,4.949364665,0.599343103,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,tramadol,DB00193
,135135,DB00207,10019974,43,9037,12,5443,0.017089689,2.158142377,1.116764796,4.499875393,0.054613599,DB0020710019974_,2.907472361,0.769247841,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,azithromycin,DB00207
,135138,DB00451,10019974,236,47035,52,15367,0.009068779,1.482737417,1.093486278,2.043874286,0.032931252,DB0045110019974_,3.413333157,0.393889985,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,135145,DB00108,10016825,50,10144,12,3283,0.458345135,1.34845436,0.707005098,2.785697038,0.625703179,DB0010810016825_,0.468879175,0.298959018,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,natalizumab,DB00108
,135147,DB00836,10021036,31,5504,27,4048,0.594375888,0.844441172,0.48686335,1.473051646,0.740276728,DB0083610021036_,0.300731206,-0.169080206,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,loperamide,DB00836
,135152,DB00381,10001480,85,29275,75,22812,0.472778204,0.883132374,0.639399092,1.221847735,0.638783282,DB0038110001480_,0.448190034,-0.124280175,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,135154,DB00404,10001480,37,19855,16,9846,0.770482443,1.1467434,0.622056439,2.209100356,0.874236414,DB0040410001480_,0.134404443,0.136926099,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,135157,DB00761,10001480,40,15267,27,8598,0.524240732,0.834349518,0.499098848,1.414893965,0.682364446,DB0076110001480_,0.382191385,-0.181102879,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,135158,DB00787,10001480,94,16906,82,17166,0.326596617,1.163964932,0.855623995,1.586080373,0.495045964,DB0078710001480_,0.703104664,0.151832222,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,135159,DB00996,10001480,65,38888,43,22382,0.485013933,0.870024606,0.582644486,1.310819343,0.649146658,DB0099610001480_,0.432096612,-0.139233785,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,135167,DB00480,10034474,51,67377,67,67595,0.16694086,0.763660654,0.519814693,1.11598969,0.306739274,DB0048010034474_,1.181757161,-0.269631758,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,135170,DB00761,10034474,85,15222,31,8594,0.041332322,1.54800848,1.014153959,2.419190685,0.108398113,DB0076110034474_,2.2219446,0.436969253,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,135171,DB00787,10034474,26,16974,30,17218,0.689073085,0.879128746,0.499225511,1.538626462,0.81249806,DB0078710034474_,0.207641753,-0.128823923,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,acyclovir,DB00787
,135188,DB01047,10013709,42,745,25,455,1,1.026021051,0.601701543,1.782216532,1,DB0104710013709_,0,0.025688264,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fluocinonide,DB01047
,135193,DB00451,10048908,124,47147,18,15401,0.000586308,2.250147282,1.365998909,3.923212109,0.003527677,DB0045110048908_,5.647115768,0.810995673,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,levothyroxine,DB00451
,135194,DB00451,10014551,67,47204,13,15406,0.091224004,1.68199059,0.91977116,3.322469465,0.197205605,DB0045110014551_,1.623508412,0.519977967,NA,10014551,Emotional disorder,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,135197,DB08880,10047895,72,3266,22,787,0.356041991,0.788669571,0.479971575,1.344276367,0.525732472,DB0888010047895_,0.642962805,-0.237407841,NA,10047895,Weight decreased,10022891,Investigations,Inv,teriflunomide,DB08880
,135203,DB00804,10013709,111,2889,24,875,0.14643356,1.400652096,0.888040236,2.292782488,0.278964024,DB0080410013709_,1.276672451,0.336937911,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dicyclomine,DB00804
,135206,DB00341,10042128,49,11356,22,5046,1,0.98968157,0.586452335,1.720775716,1,DB0034110042128_,0,-0.010372034,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,135209,DB00736,10042128,60,10531,14,5539,0.004512832,2.254062609,1.24351,4.371879114,0.018813606,DB0073610042128_,3.973174945,0.812734192,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,esomeprazole,DB00736
,135211,DB00813,10042128,52,10520,24,10144,0.002600999,2.089146652,1.263840996,3.546374331,0.012031195,DB0081310042128_,4.420252432,0.736755682,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,135212,DB00924,10042128,51,10111,11,4240,0.049659267,1.944160292,0.99937639,4.140864339,0.12437885,DB0092410042128_,2.084423132,0.664830157,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,135218,DB00341,10054236,38,11367,25,5043,0.132996479,0.674367121,0.396110485,1.166969293,0.259949433,DB0034110054236_,1.347268154,-0.393980626,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,cetirizine,DB00341
,135225,DB01060,10054236,49,8538,36,5045,0.367768165,0.804288308,0.511668728,1.275027059,0.537462071,DB0106010054236_,0.620897087,-0.217797482,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,135255,DB00264,10003553,112,29495,27,24865,1.09707414249191e-10,3.496807121,2.279639704,5.541797909,3.55130465953199e-09,DB0026410003553_,19.45595079,1.251850301,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,135259,DB01592,10021789,67,6209,33,3034,1,0.992097224,0.642989192,1.557807205,1,DB0159210021789_,0,-0.007934169,NA,10021789,Infection,10021881,Infections and infestations,Infec,iron,DB01592
,135264,DB00668,10048634,119,9972,22,4281,0.000129974,2.322021977,1.462324908,3.850036151,0.000997186,DB0066810048634_,6.910573398,0.842438348,NA,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,135272,DB00471,10053505,48,14141,9,5456,0.052870408,2.057700637,0.99773591,4.77349854,0.130439148,DB0047110053505_,2.036848459,0.721589164,NA,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,135273,DB00668,10053505,106,9985,37,4266,0.313579164,1.223953578,0.832983289,1.834392003,0.481072526,DB0066810053505_,0.731737238,0.202086257,NA,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,135281,DB00338,10042682,153,33521,63,22209,0.001312823,1.609010512,1.191771378,2.194564871,0.006887736,DB0033810042682_,4.978012874,0.475619401,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,135283,DB04854,10016173,31,750,24,1462,0.000831801,2.516791308,1.418265423,4.516298082,0.004730396,DB0485410016173_,5.353746258,0.9229848,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,febuxostat,DB04854
,135294,DB00451,10069227,39,47232,13,15406,1,0.97853095,0.511164325,1.998370224,1,DB0045110069227_,0,-0.021702863,NA,10069227,Product taste abnormal,10077536,Product issues,Prod,levothyroxine,DB00451
,135318,DB00472,10013950,47,10712,17,4295,0.782938223,1.108505566,0.623991253,2.061717409,0.881806742,DB0047210013950_,0.12578236,0.103012771,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,135323,DB00295,10049438,35,14628,32,9570,0.171230999,0.715584005,0.429963447,1.194705154,0.312523473,DB0029510049438_,1.163075698,-0.334656279,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,135347,DB00338,10067973,40,33634,33,22239,0.341800645,0.801472951,0.492675695,1.311981196,0.511024735,DB0033810067973_,0.671337285,-0.221304056,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,omeprazole,DB00338
,135350,DB00451,10067973,40,47231,36,15383,2.19635493180828e-05,0.361892752,0.224792791,0.584527307,0.000216465,DB0045110067973_,8.438082139,-1.016407376,male,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,levothyroxine,DB00451
,135356,DB00904,10067973,44,23025,56,14400,0.000427532,0.49139182,0.323193461,0.742981156,0.002708851,DB0090410067973_,5.911230556,-0.710513466,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,ondansetron,DB00904
,135361,DB00836,10046571,175,5360,37,4038,7.84302799004821e-15,3.562719586,2.48069707,5.239398675,4.69064825297877e-13,DB0083610046571_,28.38803542,1.270524182,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,loperamide,DB00836
,135381,DB09146,10021097,46,742,25,402,1,0.996875613,0.589749977,1.71995856,1,DB0914610021097_,0,-0.003129278,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,iron sucrose,DB09146
,135387,DB00798,10037660,27,780,39,605,0.015788033,0.537224321,0.312401633,0.911700684,0.051321845,DB0079810037660_,2.969638781,-0.621339541,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,gentamicin,DB00798
,135409,DB00203,10061494,42,13836,26,8912,0.901757969,1.040497981,0.622744294,1.76910582,0.957082614,DB0020310061494_,0.043865565,0.039699426,NA,10061494,Rhinovirus infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,135410,DB00374,10061494,40,17676,14,5710,0.75325773,0.922957133,0.491155411,1.838050636,0.861142111,DB0037410061494_,0.149495734,-0.080172489,NA,10061494,Rhinovirus infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,135422,DB08900,10022687,41,970,17,420,1,1.044231384,0.572586809,1.984043463,1,DB0890010022687_,0,0.043281097,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,teduglutide,DB08900
,135427,DB00007,10012378,59,1888,39,4413,1.14091732119626e-09,3.535234959,2.310675933,5.463151514,3.13364804468585e-08,DB0000710012378_,17.27848291,1.262779764,female,10012378,Depression,10037175,Psychiatric disorders,Psych,leuprolide,DB00007
,135450,DB00218,10013968,61,1381,36,914,0.671983728,1.121427856,0.724144415,1.758692077,0.800901423,DB0021810013968_,0.222017406,0.114602745,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,moxifloxacin,DB00218
,135454,DB00115,10021015,72,18353,27,10445,0.074466578,1.517623768,0.962237384,2.45912892,0.168941308,DB0011510021015_,1.778203913,0.417145801,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,cyanocobalamin,DB00115
,135459,DB01060,10021015,47,8540,17,5064,0.091509584,1.639343387,0.922850087,3.048849746,0.197684768,DB0106010021015_,1.621081597,0.494295788,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,amoxicillin,DB01060
,135462,DB00218,10037844,52,1390,22,928,0.090548651,1.577738136,0.934145305,2.747715699,0.1961247,DB0021810037844_,1.629004595,0.455992262,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,moxifloxacin,DB00218
,135466,DB09140,10037844,105,3636,52,1746,0.862928521,0.969606092,0.685391887,1.386347152,0.93655991,DB0914010037844_,0.065541787,-0.030865381,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,oxygen,DB09140
,135468,DB06403,10034474,106,21365,23,6638,0.145368306,1.431860445,0.904806279,2.357990732,0.277578433,DB0640310034474_,1.281651743,0.358974609,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,ambrisentan,DB06403
,135474,DB00193,10018627,44,19276,31,8671,0.060726883,0.638484305,0.393877454,1.046626237,0.144734652,DB0019310018627_,1.932853196,-0.448658185,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,tramadol,DB00193
,135479,DB00193,10022086,209,19111,43,8659,4.8391169087334e-07,2.202174729,1.577992464,3.136618014,7.53978588891863e-06,DB0019310022086_,11.79531677,0.789445385,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,135482,DB00351,10010774,26,640,36,828,0.896109018,0.934400442,0.535716734,1.609768102,0.956301489,DB0035110010774_,0.044682051,-0.067850194,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,megestrol acetate,DB00351
,135484,DB00530,10013709,119,1689,59,1209,0.027815672,1.44358021,1.038141764,2.025443562,0.079809504,DB0053010013709_,2.528112679,0.367126285,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,erlotinib,DB00530
,135485,DB00351,10051398,16,650,51,813,0.000927174,0.392627585,0.206942873,0.707644603,0.005176462,DB0035110051398_,5.263633557,-0.934893738,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,megestrol acetate,DB00351
,135487,DB00959,10041349,70,8008,22,4980,0.004850622,1.978605718,1.208713888,3.360302407,0.019978227,DB0095910041349_,3.913112232,0.682392414,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,135488,DB00820,10005191,37,11878,13,5803,0.366286773,1.390482568,0.721676084,2.853151662,0.535877763,DB0082010005191_,0.623849199,0.329650858,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,tadalafil,DB00820
,135489,DB08932,10015150,210,19233,61,6536,0.293276481,1.169904964,0.874543024,1.584827207,0.458882808,DB0893210015150_,0.778960422,0.156922518,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,macitentan,DB08932
,135493,DB00706,10029331,7,1068,222,15703,0.039383742,0.463629107,0.183766913,0.974779084,0.104418161,DB0070610029331_,2.259351661,-0.768670385,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,135496,DB00996,10029410,70,38883,35,22390,0.543483542,1.15168229,0.756806436,1.781523607,0.698658234,DB0099610029410_,0.358593592,0.141223735,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,135509,DB01234,10048762,32,31593,32,32856,0.900989189,1.039989068,0.61672387,1.75374187,0.956830061,DB0123410048762_,0.044129478,0.039210201,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,135511,DB08910,10048762,35,16709,29,17459,0.382474508,1.261057332,0.74844831,2.139770718,0.552563616,DB0891010048762_,0.593186709,0.231950521,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,135514,DB00490,10033371,210,3860,40,1536,9.39688049540588e-06,2.088888713,1.475200006,3.023485787,0.000102958,DB0049010033371_,9.181186336,0.736632208,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,135517,DB00656,10049119,36,11977,15,6604,0.384190607,1.32332418,0.706029975,2.603576308,0.554235619,DB0065610049119_,0.590165378,0.280146889,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,135521,DB00537,10051055,41,7516,24,4274,0.897784808,0.971432028,0.572304003,1.683322824,0.956338178,DB0053710051055_,0.044643686,-0.028983979,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,ciprofloxacin,DB00537
,135528,DB00820,10038435,150,11765,87,5729,0.20989975,0.839595001,0.63915906,1.108544954,0.36103995,DB0082010038435_,1.018766662,-0.174835645,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,tadalafil,DB00820
,135536,DB00327,10007515,84,6054,63,4199,0.673060143,0.924795636,0.657481304,1.306462038,0.801585186,DB0032710007515_,0.221164029,-0.0781825,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,hydromorphone,DB00327
,135543,DB00295,10024264,71,14592,94,9508,6.49176895731991e-06,0.492164695,0.356032577,0.677762276,7.43674643901302e-05,DB0029510024264_,9.506492018,-0.708941872,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,morphine,DB00295
,135590,DB13961,10046571,239,9218,69,6345,2.03482286332832e-11,2.384069517,1.812955431,3.169714084,7.38747499483218e-10,DB1396110046571_,21.02606493,0.868808908,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,fish oil,DB13961
,135599,DB08906,10003553,66,2127,22,1136,0.068464049,1.602048324,0.969795067,2.741709813,0.158532135,DB0890610003553_,1.841797962,0.471283013,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone furoate,DB08906
,135602,DB11089,10003553,42,10133,11,8396,0.000264418,3.163385302,1.599430261,6.818287795,0.001820454,DB1108910003553_,6.308669206,1.151642752,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,135618,DB01377,10025482,132,3664,49,2621,6.30784981625657e-05,1.92684044,1.372561582,2.743058856,0.000537271,DB0137710025482_,7.529007924,0.655881583,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,135623,DB01377,10043071,58,3738,21,2649,0.007891556,1.957074938,1.166671223,3.403625006,0.029459707,DB0137710043071_,3.524731812,0.67145098,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,magnesium oxide,DB01377
,135624,DB00051,10037377,77,25654,49,11371,0.052848481,0.69652865,0.48026588,1.018639555,0.130415653,DB0005110037377_,2.037028601,-0.361646353,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,135657,DB00624,10040753,14,548,38,4358,0.001443972,2.928973604,1.456173933,5.572744976,0.007452347,DB0062410040753_,4.899226213,1.074652056,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,testosterone,DB00624
,135658,DB00973,10040753,71,3780,23,2998,9.44158132433411e-05,2.44798995,1.506776294,4.116837085,0.000758802,DB0097310040753_,7.183769995,0.895267259,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,ezetimibe,DB00973
,135659,DB01136,10040753,105,9779,45,11070,1.43489485150521e-08,2.64125764,1.84378927,3.837897703,3.11061535437644e-07,DB0113610040753_,14.98327508,0.971255183,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,carvedilol,DB01136
,135661,DB00381,10054236,91,29269,42,22845,0.00493137,1.691099103,1.160436919,2.500388786,0.020248546,DB0038110054236_,3.899672281,0.525378674,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,135662,DB00563,10054236,64,46582,47,15301,5.71066415079207e-05,0.447285176,0.302041755,0.666648575,0.000494601,DB0056310054236_,7.611758468,-0.804558911,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,135666,DB00338,10062189,31,33643,19,22253,0.885433397,1.079211221,0.590531205,2.022433235,0.952314613,DB0033810062189_,0.048859823,0.076230423,NA,10062189,Vitamin D decreased,10022891,Investigations,Inv,omeprazole,DB00338
,135667,DB00381,10062189,43,29317,14,22873,0.003128536,2.396237942,1.285535669,4.743748219,0.014000776,DB0038110062189_,4.268642499,0.873899983,NA,10062189,Vitamin D decreased,10022891,Investigations,Inv,amlodipine,DB00381
,135675,DB11750,10013968,44,2456,30,1483,0.629270844,0.885643569,0.541664369,1.465937572,0.768324746,DB1175010013968_,0.263542789,-0.121440702,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clobetasol,DB11750
,135676,DB00005,10028740,43,128039,7,42412,0.099890922,2.034648707,0.907429874,5.36169545,0.210606632,DB0000510028740_,1.55776319,0.710323179,NA,10028740,Nasal dryness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,135689,DB04861,10003239,55,1910,26,1361,0.088040026,1.507171604,0.923780644,2.517306237,0.191964502,DB0486110003239_,1.650444809,0.410234784,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,nebivolol,DB04861
,135694,DB04861,10033425,48,1917,22,1365,0.110225222,1.553367423,0.914727472,2.715739747,0.226384589,DB0486110033425_,1.485520006,0.440425105,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,nebivolol,DB04861
,135700,DB00136,10008479,37,2055,19,1663,0.13560272,1.575713181,0.879420931,2.912278556,0.263593958,DB0013610008479_,1.333345396,0.454707983,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,calcitriol,DB00136
,135725,DB00193,10013538,69,19251,15,8687,0.008932998,2.075700329,1.174829427,3.909925855,0.032519057,DB0019310013538_,3.425928982,0.730298604,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,tramadol,DB00193
,135729,DB01075,10013538,49,19899,25,11072,0.808445029,1.090569699,0.66023226,1.84366081,0.896604841,DB0107510013538_,0.109140048,0.086700219,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,135742,DB08896,10053762,171,652,199,841,0.381052092,1.108324272,0.875718677,1.401835469,0.55106898,DB0889610053762_,0.595895287,0.102849209,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,regorafenib,DB08896
,135767,DB00030,10008479,32,2174,23,1798,0.683100493,1.150629434,0.649961977,2.067191875,0.808418727,DB0003010008479_,0.212675128,0.140309127,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,insulin human,DB00030
,135771,DB00887,10016173,66,2275,66,1749,0.153485806,0.768846985,0.534968299,1.104959823,0.288860804,DB0088710016173_,1.241810353,-0.262863309,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,bumetanide,DB00887
,135776,DB01224,10030124,43,8065,23,5894,0.261290817,1.366270266,0.804247566,2.377924742,0.422830088,DB0122410030124_,0.860784864,0.312084594,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,135777,DB00537,10028391,34,7523,23,4275,0.580926528,0.840053302,0.479880111,1.49567987,0.729383988,DB0053710028391_,0.315554953,-0.174289934,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ciprofloxacin,DB00537
,135792,DB01248,10021015,41,2659,9,1365,0.016182594,2.338186687,1.115205856,5.487839968,0.052294012,DB0124810021015_,2.950873408,0.849375709,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,docetaxel,DB01248
,135814,DB01248,10043554,51,2649,34,1340,0.246024978,0.758857015,0.479550167,1.214229302,0.404982874,DB0124810043554_,0.903910498,-0.275941905,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,docetaxel,DB01248
,135821,DB00349,10041349,64,958,55,889,0.705843964,1.079750136,0.732161168,1.596794942,0.823703986,DB0034910041349_,0.193944054,0.076729659,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,clobazam,DB00349
,135824,DB00557,10002198,44,5943,6,3061,0.000775283,3.77659437,1.601067183,10.8561581,0.004456225,DB0055710002198_,5.413453198,1.328822643,female,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,hydroxyzine,DB00557
,135831,DB00773,10021143,25,2298,31,2796,1,0.981219888,0.55376175,1.722542371,1,DB0077310021143_,0,-0.018958697,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etoposide,DB00773
,135835,DB00773,10028116,56,2267,118,2709,0.000466303,0.56716658,0.403015284,0.790155024,0.002913877,DB0077310028116_,5.838270716,-0.567102227,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,etoposide,DB00773
,135852,DB00656,10029412,33,11980,25,6594,0.271272991,0.726589645,0.41868425,1.275667198,0.434027292,DB0065610029412_,0.834647863,-0.319393411,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,135857,DB00704,10033425,98,4258,99,5095,0.248013344,1.18446053,0.883851087,1.587198361,0.407388498,DB0070410033425_,0.897988008,0.169287422,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,naltrexone,DB00704
,135859,DB00557,10052904,38,5949,20,3047,0.890404158,0.973136608,0.551131494,1.768430429,0.954638381,DB0055710052904_,0.046422669,-0.027230808,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxyzine,DB00557
,135883,DB00047,10070863,52,9233,40,8478,0.405265767,1.19368364,0.774406055,1.852204552,0.574924344,DB0004710070863_,0.553516822,0.177044022,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,135885,DB00996,10042464,90,38863,65,22360,0.18126379,0.796660877,0.572357012,1.114026302,0.325456384,DB0099610042464_,1.122526824,-0.22732619,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,135887,DB00338,10018388,43,33631,23,22249,0.451861323,1.236811218,0.728739389,2.150644694,0.619465649,DB0033810018388_,0.478898029,0.212536469,NA,10018388,Glossodynia,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,135890,DB00678,10042727,40,15559,23,10701,0.523588699,1.196089816,0.698532745,2.09419495,0.68173518,DB0067810042727_,0.383113996,0.17905775,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,135891,DB00338,10044034,92,33582,47,22225,0.165128071,1.295457161,0.9016426,1.883107649,0.30431125,DB0033810044034_,1.189704254,0.258863653,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,135892,DB00678,10044034,38,15561,22,10702,0.599378641,1.187890213,0.684463799,2.11002047,0.744048674,DB0067810044034_,0.295648824,0.172178804,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,135920,DB00480,10040882,92,67336,101,67561,0.564662806,0.913950824,0.681298238,1.224715755,0.716402216,DB0048010040882_,0.333513516,-0.089978512,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,135922,DB00480,10064265,26,67402,34,67628,0.366230493,0.767273633,0.442121335,1.317190488,0.535832499,DB0048010064265_,0.623933669,-0.264911783,NA,10064265,Skin haemorrhage,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,135927,DB00108,10008531,46,10148,18,3277,0.468734909,0.825235277,0.468555517,1.514462659,0.635136587,DB0010810008531_,0.453915206,-0.192086749,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,135936,DB01101,10031009,40,7549,14,3894,0.249836082,1.473753246,0.783810569,2.936431419,0.409397551,DB0110110031009_,0.893068588,0.387812376,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,135949,DB00047,10037423,41,9244,44,8474,0.514247057,0.854209057,0.543745109,1.33934441,0.67423104,DB0004710037423_,0.394182438,-0.157579318,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,135959,DB00343,10028596,57,8679,55,5040,0.00784394,0.601880625,0.407449936,0.889674551,0.029311625,DB0034310028596_,3.529771099,-0.507696151,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,diltiazem,DB00343
,135966,DB00343,10035598,73,8663,56,5039,0.120142923,0.758280729,0.527017215,1.0960322,0.241563279,DB0034310035598_,1.420623817,-0.276701607,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,136021,DB09072,10047340,49,6422,12,2523,0.154620133,1.604182575,0.839181025,3.319254377,0.290284748,DB0907210047340_,1.236892949,0.472614328,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,sodium oxybate,DB09072
,136023,DB01101,10028334,61,7528,21,3887,0.127842376,1.499792526,0.898812934,2.597345307,0.252592433,DB0110110028334_,1.375978027,0.405326782,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,capecitabine,DB01101
,136024,DB00051,10049848,49,25682,20,11400,0.795593313,1.087528195,0.634279876,1.932410234,0.889335739,DB0005110049848_,0.117280456,0.08390741,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,136029,DB00051,10064355,201,25530,102,11318,0.287824588,0.87361662,0.684274175,1.121045227,0.452837959,DB0005110064355_,0.792220924,-0.135113649,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,136032,DB00374,10018830,49,17667,11,5713,0.365803041,1.440425379,0.738321376,3.074278554,0.535393559,DB0037410018830_,0.624753179,0.364938472,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,136041,DB00480,10013700,259,67169,217,67445,0.053691074,1.198449458,0.996444466,1.442555617,0.131900334,DB0048010013700_,2.025708685,0.181028603,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,lenalidomide,DB00480
,136042,DB08910,10013700,41,16703,34,17454,0.355457513,1.260089303,0.779801625,2.048319932,0.525208731,DB0891010013700_,0.643959512,0.231182594,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,pomalidomide,DB08910
,136043,DB08895,10024384,75,28039,16,6630,0.790427511,1.108383242,0.639579986,2.039172782,0.886473405,DB0889510024384_,0.120504154,0.102902415,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,tofacitinib,DB08895
,136044,DB00331,10058920,36,24910,24,20728,0.437872533,1.248166304,0.724149531,2.187606993,0.606352476,DB0033110058920_,0.500293818,0.221675518,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,metformin,DB00331
,136072,DB01592,10013700,85,6191,21,3046,0.003468603,1.99131846,1.220861739,3.388003155,0.015214391,DB0159210013700_,4.185513494,0.688796962,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,iron,DB01592
,136083,DB13867,10047895,88,4462,55,2499,0.538380944,0.896117296,0.630209907,1.283730141,0.69428888,DB1386710047895_,0.364867151,-0.109683964,NA,10047895,Weight decreased,10022891,Investigations,Inv,fluticasone,DB13867
,136090,DB06228,10003285,39,15873,36,16040,0.729626955,1.094712096,0.677529004,1.773263795,0.842499814,DB0622810003285_,0.171381838,0.090491403,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,rivaroxaban,DB06228
,136095,DB00218,10020937,33,1409,25,925,0.589901204,0.866627919,0.496233601,1.530896055,0.73660585,DB0021810020937_,0.305702334,-0.143145554,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,moxifloxacin,DB00218
,136099,DB00619,10053762,55,2844,43,2451,0.683074199,1.102271421,0.72333961,1.689430737,0.808418727,DB0061910053762_,0.212675128,0.097372979,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,imatinib,DB00619
,136104,DB01006,10028813,728,5219,8,169,0.000903381,2.946386304,1.453195796,6.965525655,0.00506676,DB0100610028813_,5.285053717,1.080579438,female,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,letrozole,DB01006
,136105,DB01006,10047700,278,5669,7,170,0.855639655,1.190914858,0.558064045,3.035663645,0.930234222,DB0100610047700_,0.072318873,0.1747218,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,letrozole,DB01006
,136114,DB00316,10027452,62,65412,33,36920,0.831339393,1.060434132,0.684216023,1.670733307,0.911819568,DB0031610027452_,0.092313151,0.058678383,NA,10027452,Metastases to bone,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,136116,DB00904,10027452,34,23035,21,14435,1,1.014584476,0.571911472,1.840385291,1,DB0090410027452_,0,0.014479146,NA,10027452,Metastases to bone,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ondansetron,DB00904
,136127,DB08880,10046571,67,3271,12,797,0.390577542,1.360315865,0.725321046,2.777181118,0.560453534,DB0888010046571_,0.579008941,0.307716926,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,teriflunomide,DB08880
,136128,DB08880,10060795,59,3279,11,798,0.542302571,1.305249479,0.675183201,2.768746433,0.697549453,DB0888010060795_,0.360181867,0.266394194,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,teriflunomide,DB08880
,136144,DB00364,10002034,61,2689,36,1364,0.514571937,0.859550139,0.557076818,1.343347868,0.674490195,DB0036410002034_,0.39379814,-0.151346121,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,sucralfate,DB00364
,136149,DB00193,10013990,38,19282,23,8679,0.269175075,0.743647121,0.431529785,1.308394098,0.4316951,DB0019310013990_,0.840035727,-0.296188657,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,tramadol,DB00193
,136153,DB00537,10013990,32,7525,19,4279,0.884688794,0.957727552,0.525856438,1.790613206,0.951944941,DB0053710013990_,0.049248081,-0.043191934,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,ciprofloxacin,DB00537
,136155,DB00999,10013990,52,21378,42,12197,0.106843254,0.706415583,0.46103368,1.088030037,0.221402099,DB0099910013990_,1.507774777,-0.34755157,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,hydrochlorothiazide,DB00999
,136162,DB00537,10018867,21,7536,35,4263,7.12277292437751e-05,0.339443111,0.187498637,0.600456233,0.00059549,DB0053710018867_,7.4261258,-1.080448912,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,ciprofloxacin,DB00537
,136212,DB01076,10024378,38,25709,43,25540,0.579759441,0.877914519,0.551997235,1.391303111,0.728440578,DB0107610024378_,0.316849224,-0.130206049,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,atorvastatin,DB01076
,136214,DB01276,10047700,88,1929,53,1458,0.224035699,1.254886096,0.876041165,1.812144465,0.378590013,DB0127610047700_,0.97130142,0.227044809,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,exenatide,DB01276
,136219,DB08910,10042674,81,16663,66,17422,0.137298066,1.283161645,0.914970371,1.805189065,0.265955707,DB0891010042674_,1.324425498,0.249327068,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,136234,DB01225,10011224,90,4954,64,4576,0.122370641,1.298912845,0.929815136,1.8235632,0.24482511,DB0122510011224_,1.40721116,0.261527642,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enoxaparin,DB01225
,136255,DB00169,10031009,140,38551,38,18137,0.002132702,1.733286745,1.202955789,2.55183219,0.010258593,DB0016910031009_,4.579639597,0.550019459,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,136259,DB01373,10031009,83,22637,15,7366,0.033959465,1.800416461,1.030429247,3.363047179,0.093315475,DB0137310031009_,2.371769317,0.588018005,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,136278,DB06413,10027175,40,1516,16,658,0.883247125,1.085051702,0.589229952,2.091072827,0.951169726,DB0641310027175_,0.050062761,0.081627637,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,armodafinil,DB06413
,136286,DB01373,10038063,59,22661,23,7358,0.442546341,0.832904887,0.506207595,1.414271406,0.610598192,DB0137310038063_,0.49331616,-0.182835825,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,136291,DB00480,10024670,90,67338,93,67569,0.882470988,0.971055906,0.718435918,1.312009033,0.950859822,DB0048010024670_,0.050388628,-0.029371237,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,lenalidomide,DB00480
,136293,DB14726,10033371,35,1982,25,2823,0.008353994,1.993789136,1.1555927,3.486986332,0.030818911,DB1472610033371_,3.479626773,0.690036917,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,dabigatran,DB14726
,136294,DB01225,10050584,77,4967,35,4605,0.000392419,2.039510764,1.347969345,3.140920506,0.002523171,DB0122510050584_,5.982238915,0.712709958,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,enoxaparin,DB01225
,136295,DB00065,10021972,46,9418,30,4927,0.396605017,0.802188262,0.49493162,1.317939515,0.566170933,DB0006510021972_,0.568859244,-0.220411957,NA,10021972,Inflammatory bowel disease,10017947,Gastrointestinal disorders,Gastr,infliximab,DB00065
,136296,DB00635,10021972,34,33019,18,23776,0.326518625,1.360124488,0.746680469,2.558729878,0.495009277,DB0063510021972_,0.703178774,0.307576231,NA,10021972,Inflammatory bowel disease,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,136297,DB00472,10010774,106,10653,59,4253,0.04614978,0.71727809,0.515784219,1.005721771,0.117800144,DB0047210010774_,2.138765789,-0.332291662,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,136300,DB00472,10043071,88,10671,30,4282,0.475597448,1.177052111,0.768510083,1.848779414,0.64116317,DB0047210043071_,0.444471299,0.163013101,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,fluoxetine,DB00472
,136313,DB00795,10002855,37,4532,15,1488,0.51862888,0.809902494,0.43244596,1.593234661,0.677879667,DB0079510002855_,0.388785489,-0.210841417,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,sulfasalazine,DB00795
,136314,DB00795,10020772,35,4534,18,1485,0.148455031,0.636907536,0.34985968,1.198340735,0.281875284,DB0079510020772_,1.266290562,-0.451130789,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,sulfasalazine,DB00795
,136317,DB00795,10047899,44,4525,8,1495,0.145435784,1.816880374,0.843596597,4.478927891,0.277650556,DB0079510047899_,1.28139195,0.59712095,NA,10047899,Weight increased,10022891,Investigations,Inv,sulfasalazine,DB00795
,136322,DB00987,10010774,32,2072,29,2899,0.116329959,1.543699443,0.90140042,2.654111678,0.235654347,DB0098710010774_,1.44538918,0.434181771,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,cytarabine,DB00987
,136334,DB00327,10038678,35,6103,28,4234,0.608255285,0.867211195,0.511693916,1.482330043,0.751004906,DB0032710038678_,0.286343095,-0.142472739,NA,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydromorphone,DB00327
,136347,DB00327,10074903,37,6101,26,4236,1,0.988058618,0.581400478,1.702077639,1,DB0032710074903_,0,-0.012013253,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,hydromorphone,DB00327
,136348,DB00451,10067482,167,47104,45,15374,0.298775129,1.211239295,0.866389658,1.724142048,0.464747559,DB0045110067482_,0.766260904,0.191644047,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,136355,DB00451,10005425,164,47107,28,15391,0.000994333,1.913554065,1.275569288,2.969821513,0.005474665,DB0045110005425_,5.207624278,0.64896228,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,levothyroxine,DB00451
,136358,DB00472,10017944,43,10716,12,4300,0.298137988,1.43778749,0.743968451,2.998369001,0.464045825,DB0047210017944_,0.767771972,0.363105467,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,136360,DB01076,10017944,110,25637,77,25506,0.018934604,1.421255791,1.051989271,1.928313686,0.05917798,DB0107610017944_,2.827205767,0.35154084,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,136364,DB00682,10000381,31,19428,28,16336,0.795052096,0.930954598,0.540051897,1.611466411,0.888990507,DB0068210000381_,0.117668722,-0.07154477,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,136371,DB01042,10011906,21,969,36,1292,0.416938306,0.777860937,0.428524405,1.37886246,0.586085908,DB0104210011906_,0.5342889,-0.251207515,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,melphalan,DB01042
,136379,DB01073,10028116,22,1043,57,1593,0.035702737,0.589602074,0.341019102,0.986688958,0.096881893,DB0107310028116_,2.334262644,-0.528307421,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,fludarabine,DB01073
,136381,DB01073,10033661,30,1035,46,1604,1,1.010710395,0.611710334,1.647786484,1,DB0107310033661_,0,0.010653445,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,fludarabine,DB01073
,136385,DB01073,10047700,25,1040,33,1617,0.587263461,1.177805845,0.667294711,2.055165492,0.734410928,DB0107310047700_,0.308686559,0.163653254,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,fludarabine,DB01073
,136398,DB00327,10010264,94,6044,52,4210,0.203793292,1.259135745,0.88584696,1.80683995,0.353577999,DB0032710010264_,1.039651171,0.230425569,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,136399,DB00502,10010264,45,1349,47,1825,0.239973286,1.295169422,0.835736709,2.005104213,0.397849053,DB0050210010264_,0.921682609,0.258641514,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,haloperidol,DB00502
,136400,DB00904,10010264,349,22720,117,14339,9.1995940204536e-10,1.882532155,1.520978869,2.343867541,2.5738300034872e-08,DB0090410010264_,17.47528568,0.632617761,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,136407,DB00904,10019860,88,22981,7,14449,7.34216684219221e-12,7.904683693,3.677971266,20.23322526,2.87185796796164e-10,DB0090410019860_,21.97089173,2.067455456,female,10019860,Hereditary angioedema,10010331,"Congenital, familial and genetic disorders",Cong,ondansetron,DB00904
,136439,DB00316,10051076,74,65400,45,36908,0.703024855,0.928031628,0.632064632,1.376088778,0.821800601,DB0031610051076_,0.196257491,-0.074689465,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,136441,DB00476,10051076,59,17198,20,6157,0.89877044,1.056104206,0.626098819,1.853435466,0.95647837,DB0047610051076_,0.044497104,0.05458686,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,136447,DB00996,10051076,68,38885,45,22380,0.494036066,0.869716574,0.587878152,1.297667785,0.656714464,DB0099610051076_,0.42050596,-0.139587898,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,136453,DB08868,10010774,114,9088,33,2478,0.761753603,0.941939387,0.632666218,1.436934193,0.867966655,DB0886810010774_,0.141601982,-0.059814352,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,fingolimod,DB08868
,136455,DB00381,10013754,40,29320,28,22859,0.714592508,1.113730162,0.66999346,1.875204486,0.830822547,DB0038110013754_,0.185339048,0.107714888,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,136474,DB08868,10028335,81,9121,31,2480,0.106317671,0.710471554,0.46310221,1.115059878,0.220669612,DB0886810028335_,1.511088663,-0.341826369,NA,10028335,Muscle spasticity,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,136479,DB00182,10029148,34,5160,18,2834,1,1.037421739,0.568507262,1.954917571,1,DB0018210029148_,0,0.036738538,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,amphetamine,DB00182
,136486,DB11089,10029148,40,10135,26,8381,0.386466635,1.272192213,0.756780035,2.173214001,0.556602586,DB1108910029148_,0.585903783,0.240741564,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,docusate,DB11089
,136488,DB00381,10052904,181,29179,70,22817,2.67365000632161e-07,2.021892771,1.525477505,2.705422329,4.40331393584985e-06,DB0038110052904_,12.33315313,0.704034088,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,136490,DB00537,10052904,36,7521,19,4279,0.88849188,1.077993202,0.601286866,1.992147353,0.953826126,DB0053710052904_,0.047273882,0.075101166,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,ciprofloxacin,DB00537
,136493,DB00706,10052904,7,1068,65,15860,0.221868893,1.59918114,0.61702651,3.497429557,0.375850193,DB0070610052904_,0.978564637,0.469491711,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,tamsulosin,DB00706
,136499,DB00537,10061822,53,7504,21,4277,0.182246631,1.43843534,0.851681577,2.514155024,0.326685491,DB0053710061822_,1.118757374,0.363555953,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,136509,DB00776,10011906,37,1868,36,1303,0.185697019,0.71700115,0.438140463,1.174335955,0.331053048,DB0077610011906_,1.105476649,-0.332677835,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,oxcarbazepine,DB00776
,136522,DB00635,10054889,72,32981,93,23701,0.000189276,0.556374278,0.403036601,0.765379881,0.001375669,DB0063510054889_,6.588815023,-0.586314049,NA,10054889,Transaminases increased,10022891,Investigations,Inv,prednisone,DB00635
,136529,DB01281,10020751,132,8800,22,1776,0.448403139,1.210887927,0.764600035,2.003681215,0.616130924,DB0128110020751_,0.484295799,0.191353914,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,abatacept,DB01281
,136534,DB08893,10037844,41,2044,19,1039,0.784468918,1.096859276,0.618703035,2.011738949,0.882978932,DB0889310037844_,0.124453938,0.092450892,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,mirabegron,DB08893
,136545,DB01611,10013774,68,11845,8,2353,0.213509679,1.688458616,0.808694564,4.073538848,0.365644976,DB0161110013774_,1.006092427,0.523816051,NA,10013774,Dry eye,10015919,Eye disorders,Eye,hydroxychloroquine,DB01611
,136561,DB00542,10013968,67,1619,46,1378,0.290784635,1.239621725,0.832943681,1.858794944,0.456083428,DB0054210013968_,0.78507953,0.214806272,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,benazepril,DB00542
,136564,DB13867,10020919,47,4503,22,2532,0.529936356,1.201195534,0.707783849,2.098327498,0.687116507,DB1386710020919_,0.375251414,0.183317339,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,fluticasone,DB13867
,136567,DB00264,10013654,56,29551,61,24831,0.164492226,0.771409124,0.526785498,1.127790668,0.30342354,DB0026410013654_,1.192625628,-0.259536405,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,136573,DB00349,10053762,67,955,61,883,1,1.015546032,0.698090051,1.479544463,1,DB0034910053762_,0,0.01542643,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,clobazam,DB00349
,136586,DB00761,10012601,49,15258,31,8594,0.641370837,0.890298937,0.555992465,1.445446418,0.77810544,DB0076110012601_,0.250893237,-0.116197989,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,136599,DB00472,10040979,34,10725,23,4289,0.056173641,0.591189297,0.337767898,1.0524582,0.136399461,DB0047210040979_,1.992167488,-0.525619013,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,136600,DB00641,10040979,32,14092,27,12448,0.896697329,1.046928513,0.607256283,1.817406301,0.956301489,DB0064110040979_,0.044682051,0.045860651,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,simvastatin,DB00641
,136602,DB00761,10040979,54,15253,33,8592,0.737638923,0.921766528,0.586467231,1.468705827,0.848812708,DB0076110040979_,0.16391672,-0.081463311,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,136609,DB00319,10013700,88,1304,55,1798,5.65699858479919e-06,2.205610649,1.544521762,3.172750398,6.58375947759339e-05,DB0031910013700_,9.628319534,0.791004409,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,piperacillin,DB00319
,136618,DB01033,10047700,67,1115,93,1211,0.141550593,0.782536536,0.556752225,1.095075837,0.271974891,DB0103310047700_,1.302045528,-0.245214667,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,mercaptopurine,DB01033
,136619,DB00196,10047942,84,4999,73,3212,0.069247723,0.739389904,0.532099377,1.029423175,0.159973317,DB0019610047942_,1.832748249,-0.301929886,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,fluconazole,DB00196
,136632,DB08889,10044565,22,3143,45,3840,0.048656424,0.597349447,0.340814017,1.018297001,0.122556093,DB0888910044565_,2.099186449,-0.515252998,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,carfilzomib,DB08889
,136633,DB00158,10016334,53,16762,12,8092,0.016354854,2.132127905,1.124139828,4.386154772,0.05271134,DB0015810016334_,2.942924673,0.757120497,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,136635,DB01097,10020937,78,6187,22,1481,0.52360173,0.848734578,0.521120136,1.436053259,0.681735263,DB0109710020937_,0.383113874,-0.16400877,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,leflunomide,DB01097
,136651,DB00813,10002974,30,10542,22,10146,0.404953721,1.312392242,0.731550981,2.389459873,0.574678781,DB0081310002974_,0.553944036,0.271851611,NA,10002974,Apnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,136660,DB00115,10044390,73,18352,37,10435,0.619900028,1.121850525,0.744852093,1.715548011,0.760516791,DB0011510044390_,0.273757089,0.114979576,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,136662,DB00437,10044390,25,6896,36,11510,0.597207249,1.159069973,0.666323099,1.986853634,0.742470224,DB0043710044390_,0.297772511,0.147617936,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,136673,DB00563,10025310,34,46612,20,15328,0.040834801,0.559044444,0.312574056,1.025271251,0.107312813,DB0056310025310_,2.232007222,-0.581526303,NA,10025310,Lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,methotrexate,DB00563
,136691,DB09153,10008531,110,7689,75,5624,0.653830414,1.072780398,0.790970535,1.461634997,0.787803457,DB0915310008531_,0.23850664,0.070253781,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,136711,DB01048,10019211,25,440,50,1085,0.434636275,1.23274478,0.721156563,2.060206958,0.603142016,DB0104810019211_,0.505602594,0.209243211,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,abacavir,DB01048
,136715,DB14126,10019211,36,935,36,1240,0.276477209,1.326020644,0.80509779,2.184089801,0.43991667,DB1412610019211_,0.821169955,0.28218246,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,tenofovir,DB14126
,136730,DB00586,10017944,35,7074,15,2790,0.755163906,0.920282809,0.488819957,1.816602569,0.862589717,DB0058610017944_,0.147816116,-0.083074255,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,diclofenac,DB00586
,136737,DB00363,10053762,47,4581,58,6830,0.368365908,1.208147809,0.802908677,1.809673444,0.538055696,DB0036310053762_,0.6197932,0.189088451,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,clozapine,DB00363
,136756,DB00682,10007625,41,19418,44,16320,0.276645065,0.783162757,0.49879627,1.227281168,0.440063878,DB0068210007625_,0.820835385,-0.244414742,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,warfarin,DB00682
,136765,DB00374,10060800,96,17620,12,5712,0.000690772,2.593455831,1.416896756,5.197243362,0.004047018,DB0037410060800_,5.509775058,0.952991284,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,treprostinil,DB00374
,136766,DB08932,10060800,116,19327,8,6589,6.76125266012055e-08,4.943271502,2.42517119,11.72768226,1.26992702407925e-06,DB0893210060800_,13.57655112,1.598027359,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,macitentan,DB08932
,136767,DB08932,10069841,81,19362,16,6581,0.046569211,1.720592973,0.997356359,3.154843684,0.11863459,DB0893210069841_,2.131707179,0.542668983,NA,10069841,Device alarm issue,10077536,Product issues,Prod,macitentan,DB08932
,136771,DB00381,10053425,72,29288,22,22865,6.10949623128e-05,2.554911925,1.565772684,4.328027723,0.000523685,DB0038110053425_,7.554619557,0.938017752,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,136780,DB00563,10002948,34,46612,30,15318,0.000122144,0.372451913,0.221128888,0.630293347,0.000946787,DB0056310002948_,6.962436766,-0.987647341,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,136799,DB00169,10038743,49,38642,18,18157,0.432320016,1.27906599,0.73174642,2.333706864,0.600752379,DB0016910038743_,0.509572445,0.246130116,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,136807,DB01306,10048294,30,4178,30,3836,0.795878926,0.918160842,0.533641709,1.579670785,0.889460982,DB0130610048294_,0.117139638,-0.085382695,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,insulin aspart,DB01306
,136820,DB00795,10022437,40,4529,18,1485,0.284337326,0.728678732,0.406776063,1.354712894,0.448809885,DB0079510022437_,0.8011559,-0.316522341,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,sulfasalazine,DB00795
,136842,DB00316,10052137,47,65427,21,36932,0.448698223,1.263381603,0.740333008,2.225422746,0.616307993,DB0031610052137_,0.484008452,0.233791938,NA,10052137,Ear discomfort,10013993,Ear and labyrinth disorders,Ear,acetaminophen,DB00316
,136844,DB08904,10037660,158,11452,70,3489,0.011575951,0.687686684,0.514418139,0.927187939,0.040036035,DB0890410037660_,3.21797535,-0.374421946,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,136848,DB01413,10010305,47,1173,61,1598,0.842880176,1.04960633,0.696371121,1.573656841,0.920196268,DB0141310010305_,0.083168297,0.04841517,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,cefepime,DB01413
,136850,DB01413,10029350,38,1182,63,1596,0.356951681,0.814496338,0.52586081,1.246975337,0.526646737,DB0141310029350_,0.641225284,-0.205185347,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,cefepime,DB01413
,136881,DB00321,10061822,46,7401,13,2837,0.383043684,1.356315339,0.719214086,2.740622592,0.553112302,DB0032110061822_,0.59219422,0.304771713,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,136886,DB01267,10061623,18,2834,39,3676,0.080781135,0.598710107,0.321644154,1.074504837,0.179646527,DB0126710061623_,1.716764096,-0.512977759,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,136913,DB06605,10042361,59,14014,110,12923,9.19048835119731e-06,0.494623829,0.353906564,0.685391745,0.000100861,DB0660510042361_,9.201771315,-0.703957747,NA,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,136921,DB13961,10011224,228,9229,108,6306,0.001641955,1.442448797,1.139617763,1.835087591,0.008271927,DB1396110011224_,4.794887824,0.366342223,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,136937,DB00531,10025327,33,7219,19,6497,0.127389266,1.563078845,0.862162323,2.912594018,0.251928264,DB0053110025327_,1.3786109,0.446657495,NA,10025327,Lymphopenia,10005329,Blood and lymphatic system disorders,Blood,cyclophosphamide,DB00531
,136938,DB00635,10025327,31,33022,48,23746,0.000840405,0.464417787,0.28565227,0.74495846,0.004769008,DB0063510025327_,5.345617011,-0.76697073,NA,10025327,Lymphopenia,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,136945,DB00997,10045170,43,5288,79,3435,2.17350759147792e-08,0.353612779,0.237415165,0.520458274,4.52519976570275e-07,DB0099710045170_,14.60843393,-1.039552809,male,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,doxorubicin,DB00997
,136951,DB00787,10062237,81,16919,101,17147,0.180916361,0.812793969,0.598660916,1.100585654,0.325038734,DB0078710062237_,1.123810922,-0.207277622,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,acyclovir,DB00787
,136959,DB08932,10061758,41,19402,12,6585,0.752921593,1.159600618,0.597498302,2.425291182,0.860884621,DB0893210061758_,0.14979479,0.148075651,NA,10061758,Chemotherapy,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,136961,DB00472,10003658,42,10717,23,4289,0.219071458,0.730825658,0.428976895,1.274777694,0.37238313,DB0047210003658_,0.987832037,-0.313580345,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,fluoxetine,DB00472
,136970,DB11750,10037844,138,2362,79,1434,0.71910587,1.060517941,0.791963488,1.428056278,0.834143768,DB1175010037844_,0.181349508,0.058757412,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,clobetasol,DB11750
,136972,DB01240,10007815,72,5679,18,1558,0.797274232,1.097362362,0.645359217,1.961171006,0.890347732,DB0124010007815_,0.116143182,0.092909447,NA,10007815,Catheterisation cardiac,10022891,Investigations,Inv,epoprostenol,DB01240
,136973,DB00559,10020642,50,9609,15,3291,0.775571611,1.14162453,0.629751013,2.19202589,0.877771785,DB0055910020642_,0.130368646,0.132452274,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,bosentan,DB00559
,136974,DB06403,10020937,82,21389,25,6636,1,1.017633112,0.642850396,1.663902,1,DB0640310020937_,0,0.017479452,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,136975,DB01240,10024855,108,5643,36,1540,0.30602168,0.818736803,0.554142901,1.23486393,0.472927057,DB0124010024855_,0.748814116,-0.19999261,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,epoprostenol,DB01240
,136976,DB06403,10041349,116,21355,38,6623,0.775653332,0.946734349,0.650481315,1.405650833,0.877792514,DB0640310041349_,0.13034503,-0.054736744,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,136981,DB06403,10061428,428,21043,114,6547,0.153113601,1.16807369,0.946074141,1.451795299,0.288346122,DB0640310061428_,1.243593707,0.155355973,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ambrisentan,DB06403
,136982,DB06403,10062244,96,21375,18,6643,0.047020333,1.657438143,0.993997852,2.917144566,0.119488515,DB0640310062244_,2.124535017,0.505273123,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,136989,DB00203,10033295,43,13835,40,8898,0.114176829,0.691417461,0.438552911,1.09220033,0.232376148,DB0020310033295_,1.459397892,-0.369011497,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,136997,DB01222,10047513,73,9201,38,5367,0.621951934,1.120571538,0.745956599,1.707589935,0.762162596,DB0122210047513_,0.271595366,0.113838857,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,budesonide,DB01222
,137005,DB08932,10013395,49,19394,12,6585,0.376904782,1.386406682,0.726193863,2.86571951,0.546801092,DB0893210013395_,0.603670177,0.326715279,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,macitentan,DB08932
,137009,DB00619,10035664,49,2850,45,2449,0.755402636,0.935712604,0.609060895,1.440494707,0.862768675,DB0061910035664_,0.147608671,-0.066446897,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,imatinib,DB00619
,137018,DB00820,10042674,233,11682,72,5744,0.000442527,1.591146475,1.214214831,2.106524044,0.002789072,DB0082010042674_,5.882046335,0.46445481,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,137020,DB00864,10048959,36,6833,37,8355,0.480725178,1.189678557,0.729777356,1.937772985,0.645477182,DB0086410048959_,0.437765419,0.17368315,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,137033,DB00455,10061024,35,9366,34,5084,0.016425021,0.558774691,0.338030984,0.924685509,0.052901812,DB0045510061024_,2.939317685,-0.582008944,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,loratadine,DB00455
,137039,DB00682,10051099,98,19361,17,16347,2.62568303611072e-12,4.867054977,2.888314511,8.695039939,1.10337455802031e-10,DB0068210051099_,22.92747767,1.582489027,female,10051099,Catheter site haemorrhage,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,137040,DB08932,10051099,113,19330,29,6568,0.2081256,1.323950705,0.872981014,2.067912404,0.358950257,DB0893210051099_,1.024571459,0.280620225,NA,10051099,Catheter site haemorrhage,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,137041,DB08932,10052264,227,19216,51,6546,0.006735259,1.516171906,1.113191561,2.099698587,0.025979351,DB0893210052264_,3.650453249,0.416188675,NA,10052264,Catheter site erythema,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,137042,DB00682,10052915,76,19383,19,16345,2.38989772992439e-07,3.372841561,2.01833619,5.909255312,3.98467883482795e-06,DB0068210052915_,12.43305384,1.215755582,female,10052915,Catheter placement,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,137043,DB08932,10052915,99,19344,24,6573,0.146474853,1.401611842,0.889221061,2.292091326,0.279012155,DB0893210052915_,1.276499931,0.33762289,NA,10052915,Catheter placement,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,137044,DB08932,10067996,86,19357,11,6586,0.000941687,2.660116973,1.413694242,5.530536727,0.005240788,DB0893210067996_,5.251283417,0.978370096,NA,10067996,Catheter site swelling,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,137059,DB00381,10024264,131,29229,110,22777,0.602779453,0.928029901,0.714283139,1.207615834,0.746568874,DB0038110024264_,0.292267404,-0.074691326,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,137063,DB01068,10005734,56,13707,23,6817,0.474812432,1.210872549,0.732405514,2.063808822,0.640497571,DB0106810005734_,0.445509949,0.191341214,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,clonazepam,DB01068
,137069,DB00950,10033425,103,4615,40,2016,0.581744282,1.124830252,0.770463516,1.670280313,0.730044565,DB0095010033425_,0.314649698,0.117632137,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,fexofenadine,DB00950
,137070,DB00950,10048959,101,4617,28,2028,0.033107615,1.584326286,1.029837917,2.510256028,0.091516844,DB0095010048959_,2.39123224,0.460159261,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,137075,DB00814,10002034,75,8212,38,3377,0.299358762,0.811676701,0.541122013,1.235446433,0.465380001,DB0081410002034_,0.764901,-0.20865317,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,meloxicam,DB00814
,137112,DB00669,10021097,45,6332,13,1084,0.095601654,0.592645552,0.312892333,1.201640396,0.204167166,DB0066910021097_,1.588816179,-0.523158778,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sumatriptan,DB00669
,137124,DB01098,10016288,23,8126,37,7172,0.026921497,0.548669663,0.31091695,0.949140875,0.077839328,DB0109810016288_,2.553108477,-0.600258726,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,rosuvastatin,DB01098
,137128,DB01073,10021789,17,1048,34,1616,0.469514354,0.771064259,0.401799582,1.427525753,0.635850236,DB0107310021789_,0.452792222,-0.259983564,NA,10021789,Infection,10021881,Infections and infestations,Infec,fludarabine,DB01073
,137129,DB01118,10021789,17,3046,38,4671,0.214661318,0.686065487,0.362418464,1.247919877,0.367069128,DB0111810021789_,1.002205089,-0.376782193,NA,10021789,Infection,10021881,Infections and infestations,Infec,amiodarone,DB01118
,137142,DB00019,10046571,55,18957,19,9510,0.175596668,1.45216065,0.847877034,2.592665042,0.318098159,DB0001910046571_,1.145395268,0.373052551,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,pegfilgrastim,DB00019
,137148,DB00537,10047942,69,7488,57,4241,0.040127589,0.685660018,0.474711455,0.993613101,0.105929104,DB0053710047942_,2.244985239,-0.377373374,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,ciprofloxacin,DB00537
,137149,DB01073,10047942,80,985,107,1543,0.313484502,1.171137614,0.85560631,1.597946813,0.481009902,DB0107310047942_,0.731867423,0.157975596,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,fludarabine,DB01073
,137150,DB01118,10047942,21,3042,37,4672,0.686697598,0.871676271,0.483810392,1.531991477,0.811012999,DB0111810047942_,0.209471197,-0.137337173,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,amiodarone,DB01118
,137151,DB01377,10047942,59,3737,44,2626,0.763276403,0.942279087,0.624782524,1.430358274,0.868948621,DB0137710047942_,0.140471279,-0.059453777,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,magnesium oxide,DB01377
,137168,DB00399,10042674,48,6944,24,4974,0.186855727,1.432560937,0.859063795,2.448765854,0.332554863,DB0039910042674_,1.10095043,0.359463707,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,137170,DB00399,10005483,34,6958,20,4978,0.580492453,1.216215752,0.679375934,2.232697909,0.728979664,DB0039910005483_,0.316109443,0.195744195,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,zoledronic acid,DB00399
,137171,DB00399,10020583,31,6961,28,4970,0.427311657,0.790498096,0.45812797,1.369584897,0.595890008,DB0039910020583_,0.517699178,-0.235092031,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,zoledronic acid,DB00399
,137172,DB01373,10020583,72,22648,18,7363,0.39008172,1.300401625,0.76691233,2.318350026,0.559998799,DB0137310020583_,0.57982064,0.262673159,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,calcium,DB01373
,137173,DB01373,10021015,74,22646,21,7360,0.634528523,1.145238978,0.696955235,1.959601806,0.772764779,DB0137310021015_,0.257780573,0.13561333,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,calcium,DB01373
,137184,DB00335,10021015,46,8420,27,5438,0.720343019,1.100336185,0.668867204,1.842956086,0.83495243,DB0033510021015_,0.180380526,0.095615756,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,atenolol,DB00335
,137190,DB00231,10041349,61,3235,34,2105,0.525553311,1.167354106,0.752281154,1.838658966,0.683569636,DB0023110041349_,0.380426747,0.15473974,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,temazepam,DB00231
,137193,DB00425,10042682,54,12641,13,7471,0.002203724,2.454879538,1.321073873,4.906979518,0.010525101,DB0042510042682_,4.553992305,0.898077692,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,137202,DB00476,10014011,45,17212,7,6170,0.039231896,2.304481767,1.03084628,6.059743688,0.104089067,DB0047610014011_,2.262508329,0.834855821,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,duloxetine,DB00476
,137205,DB00999,10014011,70,21360,16,12223,0.000442426,2.503477979,1.438516997,4.619911054,0.002788767,DB0099910014011_,5.882155764,0.917680957,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,137207,DB08895,10014011,123,27991,13,6633,0.003038289,2.242081255,1.26261928,4.332944044,0.013661846,DB0889510014011_,4.293148262,0.807404566,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,137213,DB06724,10018884,124,7805,48,3871,0.165081894,1.281261907,0.908999283,1.831474405,0.304247482,DB0672410018884_,1.189913825,0.247845457,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,calcium carbonate,DB06724
,137216,DB00987,10001551,35,2069,50,2878,1,0.973710078,0.611126579,1.536204602,1,DB0098710001551_,0,-0.026641681,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,cytarabine,DB00987
,137220,DB00987,10003481,29,2075,35,2893,0.610679417,1.155171454,0.678770179,1.952384954,0.752806119,DB0098710003481_,0.283947563,0.144248778,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,cytarabine,DB00987
,137221,DB01377,10003481,40,3756,18,2652,0.139971839,1.568938741,0.876715615,2.914250275,0.269822139,DB0137710003481_,1.30999228,0.450399429,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,magnesium oxide,DB01377
,137225,DB01060,10012174,90,8497,70,5011,0.08460371,0.758266841,0.547535481,1.053724154,0.186077193,DB0106010012174_,1.681593677,-0.276719923,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,amoxicillin,DB01060
,137233,DB00787,10025482,377,16623,267,16981,5.47133571529074e-06,1.442370867,1.227947515,1.696117492,6.39742256567691e-05,DB0078710025482_,9.65703028,0.366288195,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,137234,DB01060,10025482,245,8342,90,4991,5.89364989093432e-05,1.628643993,1.270557855,2.10310347,0.0005085,DB0106010025482_,7.58404494,0.487747762,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,137237,DB01060,10038435,75,8512,61,5020,0.074107855,0.725147937,0.509302753,1.035910716,0.16838181,DB0106010038435_,1.781521199,-0.321379594,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,amoxicillin,DB01060
,137252,DB00642,10013968,38,496,37,496,1,1.027007328,0.624142617,1.691261271,1,DB0064210013968_,0,0.026649066,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pemetrexed,DB00642
,137253,DB01273,10013968,51,1989,32,1243,1,0.995994445,0.623972391,1.611107785,1,DB0127310013968_,0,-0.004013599,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,varenicline,DB01273
,137254,DB00186,10017885,97,16804,34,9974,0.008337705,1.693328866,1.134048604,2.584078345,0.030767454,DB0018610017885_,3.481297828,0.526696334,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,137272,DB00541,10009657,39,3095,34,4263,0.056599612,1.579806416,0.969260758,2.586453787,0.137123443,DB0054110009657_,1.986873713,0.457302318,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,vincristine,DB00541
,137275,DB00997,10021015,69,5262,20,3494,0.000674281,2.290618777,1.372854198,3.986807951,0.003971203,DB0099710021015_,5.528686128,0.82882199,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,doxorubicin,DB00997
,137276,DB00997,10028116,114,5217,134,3380,4.85184293451062e-06,0.551240045,0.423928319,0.715741913,5.75889327313667e-05,DB0099710028116_,9.762180149,-0.595584912,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,137283,DB00567,10011224,84,4435,39,2042,1,0.991693145,0.667995863,1.495086929,1,DB0056710011224_,0,-0.008341549,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cephalexin,DB00567
,137286,DB01261,10011224,65,3716,45,3258,0.248113579,1.266371989,0.850064646,1.901072506,0.407476752,DB0126110011224_,0.897771397,0.23615611,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sitagliptin,DB01261
,137295,DB00230,10014551,71,19603,11,8640,0.000432212,2.844693431,1.496726588,5.958735743,0.002734219,DB0023010014551_,5.901909269,1.045455305,female,10014551,Emotional disorder,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,137297,DB00316,10014551,79,65395,24,36929,0.007303308,1.858814645,1.164199891,3.070565488,0.027684952,DB0031610014551_,3.586866255,0.619938997,NA,10014551,Emotional disorder,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,137298,DB00338,10014551,40,33634,11,22261,0.009275478,2.406717402,1.211627472,5.201831003,0.033515146,DB0033810014551_,3.395757817,0.878263745,NA,10014551,Emotional disorder,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,137305,DB01611,10002034,129,11784,20,2341,0.374511307,1.281329827,0.79429027,2.172103556,0.544380341,DB0161110002034_,0.60810712,0.247898466,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,hydroxychloroquine,DB01611
,137306,DB00005,10019744,56,128026,38,42381,0.001107637,0.487824871,0.317413438,0.757183177,0.005988738,DB0000510019744_,5.117874641,-0.717798809,NA,10019744,Hepatitis C,10021881,Infections and infestations,Infec,etanercept,DB00005
,137311,DB00005,10043554,36,128046,18,42401,0.157269014,0.662279682,0.366326102,1.238950464,0.293866215,DB0000510043554_,1.224630668,-0.412067331,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,etanercept,DB00005
,137312,DB00421,10043554,45,8858,43,5209,0.026425483,0.615457163,0.39547986,0.958820978,0.076699849,DB0042110043554_,2.567855541,-0.485389933,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,spironolactone,DB00421
,137313,DB00581,10043554,23,2090,31,2038,0.273842223,0.723534848,0.401401159,1.286692952,0.436887671,DB0058110043554_,0.828079162,-0.323606568,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,lactulose,DB00581
,137314,DB01255,10012378,81,2052,42,1536,0.063342592,1.443468791,0.976237495,2.161471097,0.149560473,DB0125510012378_,1.900054464,0.3670491,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,lisdexamfetamine,DB01255
,137322,DB00112,10037032,119,5814,66,4025,0.173988404,1.248200372,0.913660452,1.717647117,0.316156327,DB0011210037032_,1.151518481,0.221702811,NA,10037032,Proteinuria,10038359,Renal and urinary disorders,Renal,bevacizumab,DB00112
,137328,DB00646,10003658,45,3408,31,1969,0.473065827,0.838716733,0.51725172,1.375890821,0.639075704,DB0064610003658_,0.447732359,-0.175882254,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,nystatin,DB00646
,137330,DB00688,10003658,25,6465,30,5348,0.176663713,0.689381971,0.388237219,1.214249256,0.319587453,DB0068810003658_,1.140724325,-0.371959777,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,mycophenolate mofetil,DB00688
,137333,DB00864,10003658,29,6840,59,8333,0.023909497,0.598833829,0.369658017,0.950427945,0.071028609,DB0086410003658_,2.644672533,-0.512771133,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,tacrolimus,DB00864
,137348,DB00818,10006093,44,1376,68,1609,0.176290952,0.756694697,0.502174732,1.130222301,0.319064424,DB0081810006093_,1.142362242,-0.278795413,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,propofol,DB00818
,137351,DB00959,10006093,36,8042,23,4979,0.894070543,0.969046846,0.557991344,1.714983828,0.955860142,DB0095910006093_,0.045143671,-0.031442323,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,methylprednisolone,DB00959
,137361,DB00646,10008479,50,3403,20,1980,0.171028236,1.454504137,0.847525984,2.587355524,0.312250967,DB0064610008479_,1.163948032,0.374665043,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,137367,DB01115,10008479,74,3526,43,2225,0.702198251,1.085951454,0.732887182,1.626631273,0.82134572,DB0111510008479_,0.196811161,0.082456519,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,137373,DB11365,10008479,35,1610,23,1525,0.186780712,1.44123056,0.823570584,2.567457493,0.332455122,DB1136510008479_,1.1012504,0.365497305,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,sennosides,DB11365
,137412,DB00904,10010741,36,23033,21,14435,0.891891294,1.07436671,0.610214251,1.937743535,0.955030252,DB0090410010741_,0.046012261,0.071731381,NA,10010741,Conjunctivitis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,137425,DB00706,10011224,15,1060,217,15708,0.891778021,1.024349124,0.561462872,1.735426846,0.955008248,DB0070610011224_,0.046035302,0.02405741,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tamsulosin,DB00706
,137427,DB01012,10011224,32,10600,37,8648,0.181968302,0.705619268,0.42515813,1.165271645,0.326342362,DB0101210011224_,1.11980826,-0.348679467,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cinacalcet,DB01012
,137428,DB01115,10011224,106,3494,34,2234,0.000402908,1.993148173,1.337550566,3.037401047,0.002578628,DB0111510011224_,5.960497891,0.689715385,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nifedipine,DB01115
,137432,DB11365,10011224,31,1614,26,1522,0.690178831,1.124303067,0.642696248,1.981431375,0.813113235,DB1136510011224_,0.206884899,0.117163348,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sennosides,DB11365
,137529,DB00682,10020646,40,19419,64,16300,0.001488318,0.524630973,0.344093561,0.791363467,0.007639964,DB0068210020646_,4.874362413,-0.645060172,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,137549,DB00658,10020919,33,1270,26,1370,0.239255679,1.369003441,0.789145464,2.398080436,0.397009913,DB0065810020919_,0.923794029,0.31408306,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,sevelamer,DB00658
,137552,DB00688,10020919,36,6454,39,5339,0.247140413,0.763627622,0.470957636,1.235115135,0.406297386,DB0068810020919_,0.900669911,-0.269675014,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,mycophenolate mofetil,DB00688
,137558,DB00864,10020919,35,6834,51,8341,0.4481432,0.837618462,0.528027938,1.315017834,0.615867581,DB0086410020919_,0.484723305,-0.177192578,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,tacrolimus,DB00864
,137561,DB00959,10020919,40,8038,34,4968,0.187329941,0.727170357,0.448103143,1.186083706,0.333173253,DB0095910020919_,1.099092644,-0.3185945,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,methylprednisolone,DB00959
,137563,DB01012,10020919,36,10596,20,8665,0.179897256,1.471939005,0.828896955,2.685648638,0.32371038,DB0101210020919_,1.127906052,0.386580582,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,cinacalcet,DB01012
,137565,DB01115,10020919,47,3553,18,2250,0.073349056,1.653398373,0.939514704,3.033034056,0.167097186,DB0111510020919_,1.789179685,0.50283279,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,nifedipine,DB01115
,137578,DB00658,10021097,51,1252,43,1353,0.249181096,1.281603101,0.830780923,1.985127539,0.40859171,DB0065810021097_,0.895038886,0.248111717,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sevelamer,DB00658
,137579,DB00688,10021097,83,6407,62,5316,0.557631847,1.110711402,0.788039717,1.572653544,0.710708304,DB0068810021097_,0.341493195,0.105000713,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,mycophenolate mofetil,DB00688
,137602,DB00213,10024384,38,18857,25,13396,0.799350963,1.079820391,0.634699609,1.867372313,0.891621265,DB0021310024384_,0.114713827,0.076794723,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,pantoprazole,DB00213
,137609,DB00688,10024384,98,6392,94,5284,0.30739243,0.86184776,0.641168704,1.1590224,0.474515344,DB0068810024384_,0.745461324,-0.148676637,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,mycophenolate mofetil,DB00688
,137611,DB00722,10024384,37,25366,31,26001,0.466875125,1.22341999,0.738287656,2.039755229,0.633432919,DB0072210024384_,0.456601175,0.201650207,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,lisinopril,DB00722
,137614,DB00864,10024384,105,6764,117,8275,0.497487068,1.097905364,0.833758962,1.444280534,0.659595353,DB0086410024384_,0.416128734,0.093404149,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,tacrolimus,DB00864
,137616,DB00904,10024384,72,22997,54,14402,0.314861343,0.835017948,0.578245729,1.212072891,0.482440543,DB0090410024384_,0.728897592,-0.18030206,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,ondansetron,DB00904
,137617,DB00959,10024384,32,8046,30,4972,0.115588485,0.659187665,0.387366461,1.124446022,0.234562365,DB0095910024384_,1.450033776,-0.416747013,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,methylprednisolone,DB00959
,137626,DB01610,10024384,57,884,63,1155,0.394588169,1.182030232,0.802228291,1.738548586,0.564510424,DB0161010024384_,0.571796429,0.167233496,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,valganciclovir,DB01610
,137633,DB00213,10027417,41,18854,41,13380,0.144187057,0.709683392,0.448643645,1.122541363,0.275828431,DB0021310027417_,1.287976234,-0.342936335,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,137635,DB00343,10027417,52,8684,21,5074,0.180640723,1.446783797,0.855311693,2.531934566,0.324637043,DB0034310027417_,1.12504751,0.369343022,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,diltiazem,DB00343
,137641,DB00904,10027417,57,23012,63,14393,0.00188906,0.565919234,0.388190208,0.823420311,0.009285448,DB0090410027417_,4.679306785,-0.569303906,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,137659,DB00316,10037368,58,65416,32,36921,1,1.022981339,0.653236369,1.628350377,1,DB0031610037368_,0,0.022721246,NA,10037368,Pulmonary congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,137661,DB00338,10037368,32,33642,23,22249,0.783797454,0.920135703,0.521711299,1.647128466,0.882317605,DB0033810037368_,0.125203192,-0.083234117,NA,10037368,Pulmonary congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,137664,DB00635,10037368,39,33014,20,23774,0.236399015,1.404222144,0.799083008,2.541872537,0.393621032,DB0063510037368_,0.932366681,0.339483515,NA,10037368,Pulmonary congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,137669,DB00695,10037368,62,27987,30,20498,0.072012187,1.513636121,0.963531963,2.426066306,0.164802607,DB0069510037368_,1.803006841,0.414514783,NA,10037368,Pulmonary congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,137717,DB00688,10043071,37,6453,36,5342,0.555753456,0.850840906,0.522183515,1.387517189,0.709143678,DB0068810043071_,0.343697125,-0.161530118,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,mycophenolate mofetil,DB00688
,137718,DB00706,10043071,6,1069,59,15866,0.304016155,1.509284949,0.531236504,3.496181776,0.470602434,DB0070610043071_,0.75374163,0.411635995,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,tamsulosin,DB00706
,137723,DB01015,10043071,78,9809,68,9313,0.619080035,1.089023801,0.775575436,1.532472623,0.759989665,DB0101510043071_,0.274450444,0.0852817,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,sulfamethoxazole,DB01015
,137731,DB00343,10046571,219,8517,51,5044,1.13736402156347e-10,2.54293984,1.863359117,3.527549816,3.67493709979053e-09,DB0034310046571_,19.42172982,0.933320829,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,diltiazem,DB00343
,137736,DB11365,10046571,52,1593,31,1517,0.044919449,1.597154106,0.998476459,2.593281832,0.115410559,DB1136510046571_,2.159259432,0.468223362,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,sennosides,DB11365
,137782,DB00316,10048038,40,65434,34,36919,0.089539717,0.663818021,0.409590655,1.081328595,0.194508385,DB0031610048038_,1.637280006,-0.409747232,NA,10048038,Wound infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,137785,DB00635,10048038,35,33018,21,23773,0.588392289,1.199986755,0.679160184,2.17008354,0.735348779,DB0063510048038_,0.307410363,0.18231052,NA,10048038,Wound infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,137790,DB00695,10048038,37,28012,14,20514,0.033525779,1.935404341,1.021642422,3.876747995,0.092400662,DB0069510048038_,2.381621137,0.660316266,NA,10048038,Wound infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,137856,DB00635,10061124,25,33028,59,23735,1.79297709183869e-07,0.304511416,0.182673352,0.493969097,3.07486407941161e-06,DB0063510061124_,12.69224986,-1.189046703,male,10061124,Enterococcal infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,137865,DB00864,10061124,39,6830,48,8344,1,0.992606381,0.632624757,1.548760795,1,DB0086410061124_,0,-0.007421088,NA,10061124,Enterococcal infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,137898,DB00864,10061471,33,6836,27,8365,0.121080501,1.495537385,0.871088323,2.58851422,0.242965185,DB0086410061471_,1.414837116,0.402485597,NA,10061471,Pseudomonas infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,138015,DB00814,10010305,91,8196,30,3385,0.315573428,1.252742244,0.81933446,1.965137233,0.483227843,DB0081410010305_,0.727267011,0.225334943,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,meloxicam,DB00814
,138020,DB00158,10049414,34,16781,23,8081,0.205621371,0.711856528,0.406978119,1.266596192,0.35596805,DB0015810049414_,1.0329143,-0.339878894,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,138022,DB00563,10049414,50,46596,25,15323,0.106837589,0.657701147,0.399099063,1.109891992,0.221399088,DB0056310049414_,1.50778838,-0.419004634,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,138025,DB01104,10049414,58,15405,36,7250,0.222601294,0.758213368,0.491312512,1.184405578,0.376710985,DB0110410049414_,0.976277004,-0.276790445,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,138026,DB00158,10064355,82,16733,50,8054,0.192781872,0.789403691,0.548077035,1.146890794,0.340130991,DB0015810064355_,1.078424469,-0.23647744,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,138027,DB00421,10064355,37,8866,26,5226,0.514620582,0.838840447,0.493801157,1.444514847,0.67450623,DB0042110064355_,0.393774367,-0.175734761,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,spironolactone,DB00421
,138029,DB00588,10064355,100,16424,45,8423,0.538003322,1.139645022,0.793163406,1.660059166,0.694057292,DB0058810064355_,0.365200769,0.13071683,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,138030,DB00814,10064355,39,8248,24,3391,0.12685407,0.668111082,0.391121085,1.163342781,0.251251543,DB0081410064355_,1.381300677,-0.40330083,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,meloxicam,DB00814
,138037,DB00338,10008796,44,33630,38,22234,0.258834648,0.765540542,0.484463536,1.214710865,0.419937315,DB0033810008796_,0.867649829,-0.267173103,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,138053,DB00555,10039897,52,6995,19,3467,0.311278604,1.356474501,0.787127856,2.433518933,0.478771065,DB0055510039897_,0.736532739,0.304889055,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,138056,DB00404,10043521,47,19845,7,9855,0.00121788,3.334199365,1.496891783,8.746518834,0.006475954,DB0040410043521_,5.039659329,1.20423258,female,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,138123,DB01142,10028813,103,1637,25,759,0.003203001,1.909818728,1.212136757,3.113511534,0.01426843,DB0114210028813_,4.24970588,0.647008331,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,doxepin,DB01142
,138124,DB01142,10047700,62,1678,9,775,0.000381054,3.180575448,1.561326034,7.318855886,0.002463052,DB0114210047700_,6.006354077,1.157062139,female,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,doxepin,DB01142
,138156,DB00455,10001497,29,9372,35,5083,0.001523936,0.449404279,0.264647251,0.757812713,0.007793123,DB0045510001497_,4.854513537,-0.799832397,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,loratadine,DB00455
,138157,DB00455,10015150,116,9285,42,5076,0.023526959,1.509860429,1.050449446,2.207197945,0.070118046,DB0045510015150_,2.657575085,0.412017215,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,loratadine,DB00455
,138159,DB01238,10010144,132,5118,92,3410,0.782366312,0.955992731,0.724274699,1.2661218,0.881537144,DB0123810010144_,0.126088141,-0.045004969,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,138164,DB00451,10022611,61,47210,25,15394,0.318983582,0.795623864,0.491880497,1.323316889,0.487109626,DB0045110022611_,0.719266077,-0.228628738,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,138168,DB00177,10048959,126,4674,41,2809,0.000479341,1.846789279,1.284480316,2.704033178,0.002982832,DB0017710048959_,5.814882069,0.613448607,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,138169,DB00476,10054236,34,17223,19,6158,0.120086793,0.639831242,0.354446161,1.188377368,0.241505841,DB0047610054236_,1.42086162,-0.446550821,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,duloxetine,DB00476
,138180,DB01076,10039227,33,25714,24,25559,0.289115948,1.366698413,0.783374044,2.417375274,0.454252231,DB0107610039227_,0.78910266,0.312397914,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,138184,DB00761,10016322,249,15058,77,8548,1.66477304585212e-06,1.83567352,1.414233069,2.405645668,2.25908928808585e-05,DB0076110016322_,10.6979637,0.607411455,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,138185,DB00761,10022004,77,15230,25,8600,0.017009708,1.739161148,1.094111563,2.853158277,0.054408297,DB0076110022004_,2.91123861,0.553402898,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,138192,DB00471,10033645,41,14148,19,5446,0.47486005,0.830674679,0.470825384,1.516684974,0.640497571,DB0047110033645_,0.445509949,-0.185517042,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,138193,DB08932,10019303,384,19059,108,6489,0.084231686,1.210541199,0.973462415,1.515759053,0.185464922,DB0893210019303_,1.684889517,0.191067532,NA,10019303,Heart rate increased,10022891,Investigations,Inv,macitentan,DB08932
,138209,DB01238,10013950,51,5199,18,3484,0.018748951,1.898564783,1.088359778,3.459190403,0.05872304,DB0123810013950_,2.834923133,0.641098223,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,aripiprazole,DB01238
,138226,DB00476,10038743,62,17195,27,6150,0.399485206,0.821279891,0.514289106,1.344009951,0.569347105,DB0047610038743_,0.563265005,-0.196891313,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,138227,DB01238,10038743,62,5188,40,3462,0.91922609,1.034328119,0.682306172,1.583807194,0.964295004,DB0123810038743_,0.03635801,0.033752056,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,138228,DB01238,10051076,40,5210,23,3479,0.607739123,1.161254672,0.67727062,2.03581262,0.750621551,DB0123810051076_,0.286853681,0.149501034,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole,DB01238
,138229,DB00715,10020937,53,4790,16,2271,0.120986161,1.570407468,0.881706055,2.949923593,0.242856904,DB0071510020937_,1.41528288,0.45133512,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,paroxetine,DB00715
,138231,DB01275,10028596,38,3941,51,3298,0.031856379,0.623578706,0.397539981,0.970613355,0.088791148,DB0127510028596_,2.421468314,-0.47228029,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,hydralazine,DB01275
,138232,DB00678,10030095,87,15512,48,10676,0.253551807,1.247424358,0.866320299,1.815081443,0.414053755,DB0067810030095_,0.881759471,0.221080912,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,138233,DB08910,10030095,43,16701,29,17459,0.076383052,1.550025602,0.945230965,2.575776011,0.172122982,DB0891010030095_,1.759546049,0.438271448,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,138234,DB00575,10035664,153,5091,97,3732,0.298840365,1.156227566,0.88742424,1.512435583,0.464805301,DB0057510035664_,0.766136669,0.145162608,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,clonidine,DB00575
,138235,DB08910,10046735,70,16674,38,17450,0.000984228,1.927786003,1.280076738,2.943319713,0.005433824,DB0891010046735_,5.2151122,0.656372196,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,pomalidomide,DB08910
,138242,DB14513,10040753,150,7027,32,3532,3.27665529050321e-06,2.355931264,1.596041831,3.575425629,4.08959564629045e-05,DB1451310040753_,10.10447936,0.856936091,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,magnesium,DB14513
,138243,DB00480,10044390,191,67237,156,67506,0.059832122,1.229253236,0.989407104,1.529140238,0.143179837,DB0048010044390_,1.943653834,0.206406859,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,138244,DB00087,10003549,55,1314,22,725,0.226149752,1.379176253,0.819511956,2.39572118,0.381035623,DB0008710003549_,0.96486241,0.321486403,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,alemtuzumab,DB00087
,138251,DB00773,10051398,43,2280,52,2775,1,1.006451691,0.65332727,1.543378008,1,DB0077310051398_,0,0.006430968,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,etoposide,DB00773
,138252,DB00795,10011224,59,4510,15,1488,0.418045377,1.297672881,0.724210788,2.470684123,0.587077134,DB0079510011224_,0.532599064,0.260572569,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfasalazine,DB00795
,138302,DB01076,10061225,58,25689,49,25534,0.439212584,1.176526585,0.790073101,1.758307572,0.607615935,DB0107610061225_,0.498212282,0.162566525,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,138304,DB00005,10013687,54,128028,9,42410,0.057353052,1.987412956,0.97309574,4.579410478,0.138463816,DB0000510013687_,1.977146247,0.686833771,NA,10013687,Drug eruption,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,138314,DB00956,10015150,36,5778,15,3452,0.309432983,1.433799419,0.764308406,2.823099651,0.476895102,DB0095610015150_,0.740458725,0.360327857,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocodone,DB00956
,138315,DB01097,10015150,49,6216,8,1495,0.399703025,1.47303913,0.689935968,3.60940819,0.569580332,DB0109710015150_,0.562855449,0.387327702,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,leflunomide,DB01097
,138317,DB00904,10031161,58,23011,10,14446,2.64895079054709e-05,3.641049987,1.844310968,7.993110913,0.000253881,DB0090410031161_,8.278644415,1.292272098,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,138319,DB01097,10031161,73,6192,18,1485,0.894048776,0.972627291,0.572455758,1.73708936,0.955860142,DB0109710031161_,0.045143671,-0.027754321,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,138324,DB00996,10037867,65,38888,26,22399,0.127369196,1.439960251,0.900638132,2.365448819,0.251924369,DB0099610037867_,1.378626359,0.36461551,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,138328,DB00904,10039073,58,23011,12,14444,0.000177179,3.03378958,1.610878417,6.208457656,0.001300881,DB0090410039073_,6.644713611,1.109812524,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,138329,DB00956,10039073,73,5741,12,3455,2.59508258429333e-06,3.660611221,1.970322314,7.418591929,3.32864484771589e-05,DB0095610039073_,10.3103602,1.297630134,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocodone,DB00956
,138334,DB00005,10037575,60,128022,13,42406,0.177525669,1.528755655,0.829873984,3.036264275,0.320683266,DB0000510037575_,1.137301354,0.424454107,NA,10037575,Pustular psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,138335,DB08896,10003239,20,803,32,1008,0.47930819,0.78465915,0.421865592,1.426984947,0.644364554,DB0889610003239_,0.439490635,-0.242505859,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,regorafenib,DB08896
,138339,DB00635,10018916,24,33029,30,23764,0.052432234,0.575610215,0.321931957,1.018707038,0.129581916,DB0063510018916_,2.04344204,-0.552324557,NA,10018916,Haemolytic anaemia,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,138343,DB01062,10003988,110,4376,29,1716,0.068945577,1.487387683,0.976110274,2.332485602,0.159422432,DB0106210003988_,1.836197795,0.397021349,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,oxybutynin,DB01062
,138345,DB00363,10010774,29,4599,72,6816,0.01886447,0.596967545,0.373293274,0.932275726,0.059023045,DB0036310010774_,2.829827321,-0.51589253,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,clozapine,DB00363
,138346,DB00199,10028813,162,2548,23,677,0.004776533,1.871069875,1.192948686,3.060817951,0.019722146,DB0019910028813_,3.926013125,0.626510393,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,erythromycin,DB00199
,138359,DB00338,10024774,82,33592,70,22202,0.115835931,0.774247599,0.555618359,1.081286927,0.23494328,DB0033810024774_,1.448411156,-0.255863561,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,138360,DB00787,10024774,37,16963,51,17197,0.165873568,0.735507257,0.468017635,1.145969766,0.305310509,DB0078710024774_,1.186425957,-0.307194873,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,acyclovir,DB00787
,138363,DB00316,10033799,35,65439,24,36929,0.498364856,0.822989024,0.475732484,1.446372305,0.660264011,DB0031610033799_,0.415115508,-0.194812414,NA,10033799,Paralysis,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,138365,DB00316,10014363,33,65441,18,36935,1,1.034737452,0.565873131,1.952100113,1,DB0031610014363_,0,0.034147725,NA,10014363,Electrocardiogram abnormal,10022891,Investigations,Inv,acetaminophen,DB00316
,138371,DB00343,10010264,172,8564,75,5020,0.033277436,1.344266234,1.016723976,1.791641805,0.091870328,DB0034310010264_,2.387377171,0.295848313,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,138373,DB13867,10010264,119,4431,36,2518,0.000678822,1.878292656,1.279431642,2.817484659,0.00399194,DB1386710010264_,5.523478039,0.630363203,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,138379,DB00695,10025102,39,28010,16,20512,0.055372679,1.784977485,0.974455431,3.422464756,0.13496577,DB0069510025102_,2.002734088,0.579405802,NA,10025102,Lung infiltration,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,138382,DB01234,10025102,32,31593,28,32860,0.52093849,1.18868519,0.693120067,2.049443416,0.679934862,DB0123410025102_,0.385758277,0.172847814,NA,10025102,Lung infiltration,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,138397,DB00264,10002544,40,29567,10,24882,0.000185075,3.366005748,1.653865993,7.551303226,0.001350745,DB0026410002544_,6.607098837,1.213726804,female,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,138398,DB00788,10043554,42,9314,35,5026,0.071711945,0.647536292,0.403033459,1.046240376,0.164258505,DB0078810043554_,1.806313842,-0.434580438,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,naproxen,DB00788
,138412,DB00656,10022061,91,11922,10,6609,6.48414143924916e-09,5.043591823,2.619118353,10.88321514,1.51984234403256e-07,DB0065610022061_,15.69948904,1.618118492,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,138414,DB00956,10022061,44,5770,9,3458,0.001575723,2.929651476,1.409272448,6.834404383,0.008001908,DB0095610022061_,4.828075287,1.074883466,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,138423,DB00996,10022112,58,38895,9,22416,3.54478954418784e-05,3.713999388,1.82710884,8.528691809,0.000328601,DB0099610022112_,8.020666528,1.312109298,female,10022112,Injection site warmth,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,138426,DB00656,10053425,63,11950,9,6610,1.80467720739973e-05,3.871750753,1.913717378,8.862085455,0.000182446,DB0065610053425_,8.609056732,1.353706796,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,138437,DB00715,10047942,49,4794,10,2277,0.011388029,2.327116721,1.161787891,5.162644852,0.039495231,DB0071510047942_,3.231575361,0.844630043,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,paroxetine,DB00715
,138439,DB00668,10020772,95,9996,53,4250,0.124739808,0.762093395,0.537895661,1.089813109,0.248189787,DB0066810020772_,1.393561555,-0.271686165,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,epinephrine,DB00668
,138440,DB01590,10012174,80,4658,79,2788,0.002125676,0.606184339,0.436954705,0.841032025,0.010228537,DB0159010012174_,4.582573706,-0.50057115,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,everolimus,DB01590
,138441,DB01590,10043554,42,4696,24,2843,0.898787241,1.059463435,0.625414784,1.833198525,0.95647837,DB0159010043554_,0.044497104,0.057762587,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,everolimus,DB01590
,138442,DB01590,10035742,182,4556,31,2836,7.44344620645019e-14,3.654023092,2.478439129,5.55053519,3.88581893816372e-12,DB0159010035742_,26.27368736,1.295828778,female,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,everolimus,DB01590
,138468,DB00497,10020993,25,19242,31,16344,0.179839107,0.68500743,0.387600527,1.199267114,0.323638978,DB0049710020993_,1.128126649,-0.378325594,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,138476,DB01306,10021097,68,4140,78,3788,0.181840843,0.797696204,0.565827103,1.122213754,0.326223778,DB0130610021097_,1.120171697,-0.226027451,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,insulin aspart,DB01306
,138522,DB01050,10009802,58,18050,7,9364,2.02322734495198e-05,4.297877879,1.957769515,11.16661283,0.000201709,DB0105010009802_,8.508685379,1.458121384,female,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,ibuprofen,DB01050
,138523,DB01050,10019851,41,18067,14,9357,0.201123519,1.516701925,0.809421814,3.014039935,0.350333446,DB0105010019851_,1.048869876,0.416538191,NA,10019851,Hepatotoxicity,10019805,Hepatobiliary disorders,Hepat,ibuprofen,DB01050
,138529,DB00169,10015137,44,38647,13,18162,0.156223616,1.590574213,0.841171188,3.219707425,0.292386769,DB0016910015137_,1.229677802,0.464095091,NA,10015137,Eructation,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,138545,DB00983,10037087,54,3447,18,1722,0.165337453,1.498587068,0.862010645,2.723913418,0.304590338,DB0098310037087_,1.188787558,0.40452271,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,formoterol,DB00983
,138553,DB00563,10025197,83,46563,30,15318,0.662897413,0.910151292,0.592704236,1.43241484,0.794494909,DB0056310025197_,0.230048701,-0.094144439,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,methotrexate,DB00563
,138562,DB01068,10046543,46,13717,28,6812,0.389399188,0.815884236,0.498755337,1.356813045,0.559324444,DB0106810046543_,0.581025573,-0.203482801,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,clonazepam,DB01068
,138567,DB00745,10011224,47,2530,17,1066,0.679308562,1.164836882,0.653037367,2.174267396,0.80595931,DB0074510011224_,0.215722021,0.152581061,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,modafinil,DB00745
,138569,DB00028,10012378,44,13414,13,5602,0.310265033,1.413529434,0.747011419,2.862808567,0.477659319,DB0002810012378_,0.738857523,0.346089721,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,human immunoglobulin g,DB00028
,138591,DB00515,10037377,40,1830,51,2100,0.67123695,0.900073162,0.576783971,1.395964218,0.800526126,DB0051510037377_,0.22248611,-0.105279227,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cisplatin,DB00515
,138594,DB00745,10022437,74,2503,26,1057,0.505121396,1.20183873,0.754519932,1.969856753,0.666037066,DB0074510022437_,0.406409956,0.183852659,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,modafinil,DB00745
,138595,DB00745,10042458,79,2498,34,1049,0.916755819,0.975739448,0.640350034,1.514798155,0.962914154,DB0074510042458_,0.037791016,-0.024559687,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,modafinil,DB00745
,138649,DB00950,10012378,83,4635,22,2034,0.0414438,1.655493946,1.021116303,2.790978687,0.108630861,DB0095010012378_,2.219799743,0.504099421,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,fexofenadine,DB00950
,138660,DB00722,10016338,43,25360,16,26016,0.000350102,2.757063089,1.521110085,5.24555963,0.002294872,DB0072210016338_,6.077078,1.014166015,female,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,138678,DB00706,10027175,14,1061,136,15789,0.128606768,1.531825061,0.812880401,2.671648856,0.253643135,DB0070610027175_,1.371826979,0.426459875,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,138679,DB00761,10027175,166,15141,46,8579,7.24893116331704e-06,2.044656321,1.465261396,2.90296451,8.18287118865314e-05,DB0076110027175_,9.410882375,0.715229717,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,138681,DB00564,10042458,41,2563,13,1450,0.085672119,1.784035698,0.933407004,3.641193322,0.187790655,DB0056410042458_,1.672427473,0.578878044,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,carbamazepine,DB00564
,138683,DB00669,10042458,46,6331,8,1089,1,0.989062653,0.460599702,2.433191906,1,DB0066910042458_,0,-0.0109976,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,sumatriptan,DB00669
,138685,DB00904,10042458,75,22994,21,14435,0.000698072,2.241994554,1.366083114,3.832704921,0.004081595,DB0090410042458_,5.501267451,0.807365895,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,138689,DB00888,10005191,26,651,37,728,0.369472552,0.785949509,0.451610127,1.34989973,0.539113247,DB0088810005191_,0.617829624,-0.240862726,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,mechlorethamine,DB00888
,138690,DB00888,10015150,64,613,69,696,0.785145503,1.053115749,0.72434825,1.529268096,0.883456745,DB0088810015150_,0.123912948,0.05175315,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,mechlorethamine,DB00888
,138692,DB00888,10037844,40,637,39,726,0.562409874,1.168811886,0.72289558,1.891202576,0.714669738,DB0088810037844_,0.335934747,0.155987751,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,mechlorethamine,DB00888
,138704,DB00334,10047700,120,2729,55,2757,1.01567348596366e-06,2.203919391,1.581306065,3.104400758,1.45160817737144e-05,DB0033410047700_,11.14025344,0.790237317,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,olanzapine,DB00334
,138720,DB00588,10021036,33,16491,43,8425,5.03549542218945e-05,0.392088354,0.241170177,0.632283785,0.000444677,DB0058810021036_,7.718163227,-0.936268072,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,fluticasone propionate,DB00588
,138729,DB11365,10002855,37,1608,13,1535,0.001479844,2.71636481,1.404583863,5.591249005,0.007606118,DB1136510002855_,4.878802368,0.999294519,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,sennosides,DB11365
,138742,DB00264,10048561,20,29587,31,24861,0.034586369,0.542121098,0.292791278,0.982171155,0.094594737,DB0026410048561_,2.358153437,-0.612265875,NA,10048561,Stent placement,10042613,Surgical and medical procedures,Surg,metoprolol,DB00264
,138753,DB01611,10007559,87,11826,19,2342,0.693811788,0.906790751,0.546076758,1.581165586,0.815655918,DB0161110007559_,0.203762682,-0.09784356,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,hydroxychloroquine,DB01611
,138755,DB01611,10035598,39,11874,17,2344,0.010217854,0.452902724,0.249773144,0.855367055,0.036180031,DB0161110035598_,3.319247948,-0.792077915,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxychloroquine,DB01611
,138783,DB00482,10012174,48,8211,22,3049,0.419436462,0.810168932,0.478767454,1.411928556,0.588423413,DB0048210012174_,0.5303085,-0.210512495,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,celecoxib,DB00482
,138785,DB00169,10016165,32,38659,24,18151,0.08607588,0.626019285,0.357214494,1.111062047,0.188471365,DB0016910016165_,1.668809192,-0.468374101,NA,10016165,Failure to thrive,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,138786,DB00451,10016165,39,47232,25,15394,0.012579986,0.508420098,0.299935533,0.876898685,0.042751946,DB0045110016165_,3.152340563,-0.676447208,NA,10016165,Failure to thrive,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,138788,DB00497,10016165,32,19235,20,16355,0.330124562,1.360422733,0.754234516,2.510734149,0.49876845,DB0049710016165_,0.695613318,0.307795485,NA,10016165,Failure to thrive,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,138814,DB01592,10038695,40,6236,15,3052,0.471627078,1.305120414,0.70405516,2.547524657,0.637802389,DB0159210038695_,0.449726778,0.266295308,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iron,DB01592
,138833,DB06674,10013709,1013,3493,297,1193,0.039323967,1.164919489,1.005747419,1.351687392,0.10429124,DB0667410013709_,2.260567911,0.152651977,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,golimumab,DB06674
,138846,DB00169,10062544,54,38637,14,18161,0.050276983,1.813000739,0.992821848,3.535395349,0.125507431,DB0016910062544_,2.07539031,0.594983339,NA,10062544,Tooth fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,138849,DB00404,10013395,48,19844,36,9826,0.063433185,0.660209948,0.419397048,1.047792454,0.149678287,DB0040410013395_,1.899267043,-0.415197392,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,138854,DB00404,10013916,39,19853,16,9846,0.56925578,1.208835742,0.659764553,2.318394805,0.720198377,DB0040410013916_,0.328228582,0.1896577,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,138859,DB00404,10018100,46,19846,9,9853,0.009110788,2.53745823,1.2265411,5.898957694,0.033051833,DB0040410018100_,3.40967824,0.931162883,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,138876,DB01015,10044565,89,9798,70,9311,0.264732396,1.20822017,0.872279504,1.679137663,0.426665708,DB0101510044565_,0.851754459,0.189148343,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,138903,DB00028,10061520,95,13363,28,5587,0.112424037,1.418567189,0.92101478,2.249129089,0.229724866,DB0002810061520_,1.470872919,0.349647341,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,138914,DB00682,10043882,30,19429,29,16335,0.60333089,0.869749707,0.504187359,1.502439374,0.747005462,DB0068210043882_,0.291682783,-0.139549801,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,warfarin,DB00682
,138917,DB00264,10009887,72,29535,71,24821,0.355781813,0.852233538,0.605134567,1.200501151,0.525473046,DB0026410009887_,0.643456382,-0.159894684,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,138918,DB00641,10009887,37,14087,36,12439,0.725199644,0.907544603,0.557487761,1.478706126,0.838917025,DB0064110009887_,0.175643475,-0.097012564,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,138919,DB00761,10009887,83,15224,34,8591,0.122958148,1.377553723,0.913008536,2.120109653,0.245671989,DB0076110009887_,1.403758009,0.320309262,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,138926,DB00215,10013950,56,11047,26,5250,1,1.023615483,0.631310037,1.700388849,1,DB0021510013950_,0,0.023340951,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,138928,DB00433,10013950,75,7581,54,5966,0.656474223,1.093032082,0.758823854,1.5834711,0.789956965,DB0043310013950_,0.23577681,0.088955561,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,138929,DB00788,10013950,44,9312,24,5037,1,0.991676025,0.589183783,1.707095346,1,DB0078810013950_,0,-0.008358813,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,naproxen,DB00788
,138932,DB00351,10016256,77,589,107,757,0.635317983,0.924905786,0.667331446,1.277481392,0.773400485,DB0035110016256_,0.256958273,-0.078063399,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,megestrol acetate,DB00351
,138933,DB01296,10016256,113,1336,86,897,0.407794329,0.882246055,0.65178388,1.197486287,0.577230078,DB0129610016256_,0.549514343,-0.125284288,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,glucosamine,DB01296
,138934,DB06186,10016256,94,2115,154,3492,0.946743055,1.007792265,0.766798259,1.318904669,0.985218489,DB0618610016256_,0.014891846,0.007762062,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ipilimumab,DB06186
,138935,DB06723,10016256,71,959,43,567,0.920167387,0.976236302,0.649162835,1.482477181,0.964685696,DB0672310016256_,0.035952934,-0.02405061,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,aluminum hydroxide,DB06723
,138940,DB06724,10017577,127,7802,31,3888,0.000227555,2.041453299,1.366577783,3.134956803,0.001605931,DB0672410017577_,6.43405167,0.713661956,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,138943,DB00316,10020942,36,65438,17,36936,0.668053026,1.19525804,0.654131699,2.269747041,0.798342817,DB0031610020942_,0.225217179,0.178362096,NA,10020942,Hypoalbuminaemia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,138953,DB00904,10020942,23,23046,32,14424,0.00339696,0.449854919,0.251267359,0.793518121,0.01495755,DB0090410020942_,4.202539068,-0.798830151,NA,10020942,Hypoalbuminaemia,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,138982,DB00316,10025256,102,65372,58,36895,1,0.992538389,0.711967163,1.395120909,1,DB0031610025256_,0,-0.007489588,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,138984,DB00695,10025256,30,28019,23,20505,0.889945639,0.954525272,0.535917233,1.72123133,0.954386794,DB0069510025256_,0.046686245,-0.04654116,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,furosemide,DB00695
,138990,DB00904,10025256,77,22992,35,14421,0.120309614,1.379868311,0.913474275,2.121903187,0.241787461,DB0090410025256_,1.419696197,0.321988068,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,ondansetron,DB00904
,139000,DB06186,10028372,25,2184,51,3595,0.406791251,0.806942873,0.477574161,1.331040343,0.576306791,DB0618610028372_,0.551115137,-0.214502402,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,ipilimumab,DB06186
,139002,DB06724,10028372,87,7842,39,3880,0.635581604,1.103708796,0.746680892,1.657670477,0.77352116,DB0672410028372_,0.256802253,0.098676141,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,139005,DB00788,10040047,50,9306,49,5012,0.004075102,0.549570315,0.36253511,0.833543746,0.017347732,DB0078810040047_,4.054293517,-0.598618551,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,naproxen,DB00788
,139008,DB09020,10040047,39,1915,48,1556,0.063419827,0.66026921,0.418991039,1.034810285,0.149659668,DB0902010040047_,1.899391443,-0.415107634,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,bisacodyl,DB09020
,139014,DB06186,10003481,43,2166,48,3598,0.064019162,1.487934526,0.959035689,2.30239368,0.150679629,DB0618610003481_,1.892599361,0.397388934,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,ipilimumab,DB06186
,139015,DB00370,10012174,67,4474,54,3609,1,1.000856701,0.68692389,1.464082076,1,DB0037010012174_,0,0.000856334,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,mirtazapine,DB00370
,139016,DB00331,10019663,22,24924,32,20720,0.054548745,0.571552149,0.316291513,1.015023279,0.133539514,DB0033110019663_,2.013357862,-0.55939955,NA,10019663,Hepatic failure,10019805,Hepatobiliary disorders,Hepat,metformin,DB00331
,139019,DB00370,10028372,20,4521,41,3622,0.00042115,0.390847474,0.216553328,0.684010596,0.002672977,DB0037010028372_,5.924562632,-0.939437888,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,mirtazapine,DB00370
,139023,DB06186,10061428,32,2177,54,3592,1,0.977766968,0.608877392,1.547239058,1,DB0618610061428_,0,-0.022483912,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ipilimumab,DB06186
,139025,DB00451,10017918,118,47153,25,15394,0.05150468,1.540884025,0.993944516,2.478122234,0.12782964,DB0045110017918_,2.057056841,0.432356294,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,139038,DB00590,10002034,32,744,43,1909,0.008877626,1.909068198,1.159407646,3.114646523,0.032364551,DB0059010002034_,3.430691574,0.646615268,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,doxazosin,DB00590
,139067,DB00421,10055798,70,8833,32,5220,0.258179778,1.292714782,0.838117961,2.033096792,0.419098685,DB0042110055798_,0.869648861,0.256744489,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,spironolactone,DB00421
,139074,DB01224,10061284,52,8056,26,5891,0.134633767,1.462472598,0.895534429,2.443077992,0.262117514,DB0122410061284_,1.338962348,0.380128564,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,139076,DB00065,10001760,173,9291,15,4942,2.06388407031452e-17,6.134831376,3.612342703,11.21182114,1.67177789794198e-15,DB0006510001760_,34.02488873,1.813982592,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,infliximab,DB00065
,139082,DB01306,10012607,30,4178,38,3828,0.222643735,0.723371036,0.431887065,1.201609879,0.376758552,DB0130610012607_,0.976150743,-0.323832999,NA,10012607,Diabetes mellitus inadequate control,10027433,Metabolism and nutrition disorders,Metab,insulin aspart,DB01306
,139085,DB00316,10012671,64,65410,46,36907,0.233117692,0.785048503,0.528990735,1.173077859,0.389678434,DB0031610012671_,0.942433408,-0.242009776,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,139087,DB01306,10022437,51,4157,34,3832,0.156485572,1.382669203,0.876490774,2.206065469,0.292714436,DB0130610022437_,1.228557767,0.324015836,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,insulin aspart,DB01306
,139089,DB00996,10024690,31,38922,21,22404,0.566974276,0.849723091,0.472740559,1.556279467,0.718212957,DB0099610024690_,0.330989157,-0.162844758,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,gabapentin,DB00996
,139096,DB01306,10047942,34,4174,44,3822,0.139461906,0.707596836,0.437596983,1.135305844,0.269066074,DB0130610047942_,1.312798302,-0.345880789,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,insulin aspart,DB01306
,139099,DB00060,10058080,43,9465,11,2454,1,1.013514383,0.513022941,2.18269197,1,DB0006010058080_,0,0.013423878,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,interferon beta-1a,DB00060
,139117,DB00512,10025482,58,4679,37,5061,0.013025017,1.695440871,1.101189055,2.639751994,0.043948982,DB0051210025482_,3.124725824,0.527942808,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,139118,DB01212,10025482,46,1973,12,1929,1.38146814147163e-05,3.746439842,1.945725509,7.795800113,0.000144267,DB0121210025482_,8.843847943,1.320806014,female,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ceftriaxone,DB01212
,139122,DB01212,10040070,40,1979,20,1921,0.01846897,1.941061,1.103635525,3.51806783,0.05801349,DB0121210040070_,2.847079714,0.663234731,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,ceftriaxone,DB01212
,139128,DB00512,10054889,29,4708,51,5047,0.033102312,0.609604174,0.371873171,0.982066083,0.091510519,DB0051210054889_,2.391301351,-0.494945427,NA,10054889,Transaminases increased,10022891,Investigations,Inv,vancomycin,DB00512
,139129,DB01212,10054889,22,1997,34,1907,0.0814422,0.617976332,0.342973114,1.092167479,0.180769661,DB0121210054889_,1.710531647,-0.481305119,NA,10054889,Transaminases increased,10022891,Investigations,Inv,ceftriaxone,DB01212
,139142,DB00043,10000081,49,6364,14,2286,0.566001126,1.257184472,0.681451088,2.470612439,0.717464294,DB0004310000081_,0.332032097,0.228874675,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,omalizumab,DB00043
,139147,DB00635,10002383,18,33035,34,23760,0.001005773,0.380777737,0.20242338,0.693582697,0.005531281,DB0063510002383_,5.19733593,-0.96553944,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,prednisone,DB00635
,139150,DB00043,10003549,60,6353,22,2278,0.900366519,0.977921975,0.589522808,1.678344123,0.956698706,DB0004310003549_,0.044266769,-0.022325392,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,139155,DB01222,10025082,69,9205,42,5363,0.843660488,0.957180278,0.641909444,1.442309906,0.920827008,DB0122210025082_,0.082483091,-0.043763527,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,139182,DB00471,10062244,73,14116,14,5451,0.015810675,2.013485855,1.12559141,3.867047285,0.051376385,DB0047110062244_,2.968576641,0.699867476,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,139183,DB00588,10062244,75,16449,34,8434,0.61254869,1.131022859,0.744036774,1.75131784,0.754420501,DB0058810062244_,0.281805373,0.123122409,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,139186,DB00471,10062352,68,14121,21,5444,0.408610973,1.248339043,0.754908777,2.146576846,0.578042423,DB0047110062352_,0.548108016,0.221813902,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,montelukast,DB00471
,139187,DB01222,10062352,48,9226,21,5384,0.317257171,1.333844923,0.782489952,2.34811657,0.485099603,DB0122210062352_,0.723401042,0.288065691,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,budesonide,DB01222
,139195,DB01050,10040560,38,18070,16,9355,0.56646157,1.22951535,0.669029676,2.363265058,0.717822942,DB0105010040560_,0.331532339,0.206620067,NA,10040560,Shock,10047065,Vascular disorders,Vasc,ibuprofen,DB01050
,139200,DB00065,10048959,103,9361,46,4911,0.387059422,1.174668821,0.820577374,1.704251809,0.557166315,DB0006510048959_,0.584891493,0.160986253,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,139221,DB00169,10061284,62,38629,28,18147,0.910368456,1.04020377,0.65547726,1.689100756,0.959579535,DB0016910061284_,0.041260075,0.039416627,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,139241,DB00099,10003239,35,2350,27,1928,0.897890396,1.063516021,0.622944168,1.833837776,0.956338178,DB0009910003239_,0.044643686,0.06158042,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,filgrastim,DB00099
,139253,DB01050,10024384,37,18071,16,9355,0.663786687,1.197104731,0.649357414,2.306258979,0.79520683,DB0105010024384_,0.229153035,0.179905917,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,ibuprofen,DB01050
,139265,DB00843,10001497,34,2160,43,2130,0.301977129,0.779762276,0.480223518,1.257181199,0.46829415,DB0084310001497_,0.758658654,-0.248766181,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,donepezil,DB00843
,139274,DB08868,10035664,97,9105,39,2472,0.045343104,0.675292805,0.459848899,1.008832739,0.116243391,DB0886810035664_,2.152069091,-0.392608897,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,fingolimod,DB08868
,139286,DB00567,10020751,44,4475,13,2068,0.196898212,1.564011508,0.825157954,3.172287495,0.345260892,DB0056710020751_,1.06345494,0.447254,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,cephalexin,DB00567
,139288,DB00567,10046735,70,4449,32,2049,1,1.007460231,0.651813985,1.587608989,1,DB0056710046735_,0,0.007432541,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,cephalexin,DB00567
,139290,DB00374,10053459,44,17672,11,5713,0.530902606,1.293095118,0.656613549,2.778266826,0.687850894,DB0037410053459_,0.374183189,0.257038661,NA,10053459,Secretion discharge,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,139295,DB01136,10003119,33,9851,28,11087,0.304718294,1.326421275,0.776655082,2.280102518,0.471508822,DB0113610003119_,0.751817467,0.282484545,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,carvedilol,DB01136
,139326,DB00736,10029410,35,10556,16,5537,0.768113493,1.147401143,0.61792338,2.222186915,0.872773231,DB0073610029410_,0.136079515,0.13749951,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,esomeprazole,DB00736
,139329,DB01076,10040831,33,25714,26,25557,0.434866651,1.261472854,0.731514415,2.19693221,0.603302453,DB0107610040831_,0.505336628,0.23227997,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,139340,DB00275,10035664,49,2011,34,1203,0.566112942,0.862170214,0.541971453,1.385668607,0.717539729,DB0027510035664_,0.331926962,-0.148302564,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,olmesartan,DB00275
,139388,DB08896,10000087,46,777,45,995,0.234010227,1.308820825,0.839032943,2.042855311,0.390822431,DB0889610000087_,0.939501963,0.269126598,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,regorafenib,DB08896
,139391,DB00351,10003549,46,620,82,782,0.076894201,0.707711076,0.474604788,1.044887991,0.173015244,DB0035110003549_,1.75437557,-0.345719354,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,megestrol acetate,DB00351
,139397,DB00863,10048294,32,10641,42,5798,0.000206871,0.415162102,0.253344082,0.674366421,0.001482038,DB0086310048294_,6.514337276,-0.879086227,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,ranitidine,DB00863
,139408,DB00295,10028836,57,14606,22,9580,0.037526684,1.69932649,1.021910301,2.921296869,0.100630382,DB0029510028836_,2.296301062,0.53023199,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,139412,DB09130,10013941,96,6774,8,113,0.000411123,0.20028268,0.094572272,0.488627272,0.002621023,DB0913010013941_,5.944190639,-1.608025512,male,10013941,Dyspareunia,10038604,Reproductive system and breast disorders,Repro,copper,DB09130
,139415,DB00334,10006093,21,2828,39,2773,0.01911929,0.528050799,0.294320675,0.922640908,0.059646374,DB0033410006093_,2.819321919,-0.63856279,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,olanzapine,DB00334
,139417,DB00334,10014387,46,2803,60,2752,0.169739894,0.752757734,0.499341997,1.12833057,0.310621584,DB0033410014387_,1.169179879,-0.284011837,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,olanzapine,DB00334
,139420,DB00215,10035669,23,11080,38,5238,1.50868585619331e-06,0.286189017,0.162565053,0.493383788,2.06917859274934e-05,DB0021510035669_,10.78577375,-1.251102788,male,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,citalopram,DB00215
,139430,DB01240,10039101,82,5669,15,1561,0.170810166,1.505190805,0.858506021,2.819177545,0.311934385,DB0124010039101_,1.164962416,0.408919671,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,139452,DB00169,10009657,59,38632,42,18133,0.042335726,0.659360383,0.436284553,1.004457956,0.11036344,DB0016910009657_,2.20397636,-0.41648503,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,139481,DB00115,10019303,97,18328,44,10428,0.220261818,1.254334095,0.868984752,1.835847962,0.373774615,DB0011510019303_,0.984102298,0.22660483,NA,10019303,Heart rate increased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,139483,DB00335,10019303,52,8414,18,5447,0.019789783,1.87010855,1.07473793,3.400795922,0.061294343,DB0033510019303_,2.792067732,0.625996477,NA,10019303,Heart rate increased,10022891,Investigations,Inv,atenolol,DB00335
,139487,DB00065,10000059,71,9393,13,4944,0.000183487,2.874502502,1.576156235,5.666996133,0.001341012,DB0006510000059_,6.614330618,1.055879616,female,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,infliximab,DB00065
,139491,DB06643,10068319,119,52302,9,7506,0.061018917,1.897538059,0.966001846,4.253291938,0.145325261,DB0664310068319_,1.928780869,0.640557287,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,denosumab,DB06643
,139493,DB00682,10069326,25,19434,37,16327,0.029894811,0.56766868,0.327377648,0.969023704,0.084488479,DB0068210069326_,2.471140092,-0.56621734,NA,10069326,Product substitution issue,10077536,Product issues,Prod,warfarin,DB00682
,139494,DB00542,10002424,16,1670,49,1375,1.66350015208632e-06,0.268956312,0.142122538,0.483680624,2.25852796991679e-05,DB0054210002424_,10.6982122,-1.313206322,male,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,benazepril,DB00542
,139496,DB01060,10009033,37,8550,24,5057,0.790805137,0.911845032,0.530467263,1.595248754,0.886674616,DB0106010009033_,0.120277201,-0.092285224,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amoxicillin,DB01060
,139498,DB14500,10009033,62,7747,46,4027,0.082809568,0.700614422,0.469821025,1.051513805,0.183081237,DB1450010009033_,1.697825308,-0.355797583,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,139510,DB06285,10006451,58,8792,8,1098,0.697161707,0.905460869,0.428807035,2.201886306,0.817820122,DB0628510006451_,0.201112867,-0.099311217,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,teriparatide,DB06285
,139514,DB01012,10016256,96,10536,88,8597,0.456806681,0.890149232,0.658589567,1.204359176,0.624170277,DB0101210016256_,0.471332069,-0.116366154,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,139519,DB06285,10011224,89,8761,12,1094,0.750745956,0.926114373,0.502630669,1.865789201,0.859111319,DB0628510011224_,0.151856774,-0.076757539,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,teriparatide,DB06285
,139521,DB06285,10022000,99,8751,6,1100,0.084987985,2.07393143,0.916604335,5.800965135,0.186773896,DB0628510022000_,1.677856505,0.729446048,NA,10022000,Influenza,10021881,Infections and infestations,Infec,teriparatide,DB06285
,139537,DB08931,10036653,97,6480,23,2423,0.049616246,1.576956562,0.990001934,2.610637437,0.124294784,DB0893110036653_,2.085099243,0.455496763,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,139538,DB00203,10005483,84,13794,59,8879,0.607217818,0.916438404,0.648416627,1.302548182,0.750121976,DB0020310005483_,0.28751945,-0.087260422,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,sildenafil,DB00203
,139583,DB01076,10072268,68,25679,49,25534,0.095492928,1.379905003,0.941355796,2.035792029,0.20399298,DB0107610072268_,1.589669699,0.322014658,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,atorvastatin,DB01076
,139592,DB01222,10020937,97,9177,37,5368,0.030425758,1.533450526,1.038247914,2.308052985,0.085597887,DB0122210020937_,2.458094686,0.427520442,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,139612,DB00820,10040979,35,11880,25,5791,0.167720346,0.682439997,0.396515941,1.190718064,0.307836693,DB0082010040979_,1.178185854,-0.382080673,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,139614,DB00820,10074300,117,11798,37,5779,0.019815368,1.548882725,1.060424681,2.310001016,0.061333839,DB0082010074300_,2.79142357,0.437533848,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,tadalafil,DB00820
,139626,DB01234,10005911,43,31582,39,32849,0.581126088,1.146793143,0.725815703,1.816977215,0.729530004,DB0123410005911_,0.315354783,0.136969475,NA,10005911,Body temperature increased,10022891,Investigations,Inv,dexamethasone,DB01234
,139634,DB01234,10019303,112,31513,99,32789,0.24176367,1.177116918,0.889777669,1.559229041,0.399896676,DB0123410019303_,0.916549076,0.163068159,NA,10019303,Heart rate increased,10022891,Investigations,Inv,dexamethasone,DB01234
,139658,DB01234,10037400,40,31585,26,32862,0.064863115,1.600639691,0.952783852,2.732535207,0.152219432,DB0123410037400_,1.88243217,0.470403356,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,139673,DB00480,10060795,114,67314,66,67596,0.000324141,1.734490912,1.26961575,2.386382598,0.002149624,DB0048010060795_,6.142462215,0.550713948,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,lenalidomide,DB00480
,139690,DB08895,10002855,283,27831,46,6600,0.016480501,1.458938266,1.064018457,2.040851017,0.053044753,DB0889510002855_,2.936619328,0.377708956,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,tofacitinib,DB08895
,139691,DB00814,10010774,153,8134,52,3363,0.245248671,1.216461733,0.880256795,1.704542377,0.404059253,DB0081410010774_,0.906193745,0.195946426,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,139693,DB01275,10013709,96,3883,77,3272,0.758116026,1.050578259,0.767327298,1.442334616,0.864890614,DB0127510013709_,0.145152238,0.049340735,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,139700,DB00381,10024670,37,29323,29,22858,1,0.994565571,0.594975893,1.677182722,1,DB0038110024670_,0,-0.00544925,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,amlodipine,DB00381
,139707,DB06218,10070863,59,1635,41,1395,0.358971026,1.227710556,0.804735449,1.888552038,0.5287061,DB0621810070863_,0.637322578,0.205151098,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,lacosamide,DB06218
,139708,DB00398,10000060,14,713,36,1502,0.646205489,0.819317365,0.405501225,1.568514584,0.781673134,DB0039810000060_,0.246318613,-0.199283768,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,sorafenib,DB00398
,139721,DB09053,10037087,30,2255,23,4029,0.002369727,2.330165672,1.305155782,4.211539034,0.011172785,DB0905310037087_,4.49427438,0.845939369,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ibrutinib,DB09053
,139723,DB00471,10052904,88,14101,16,5449,0.004073851,2.125278221,1.237282797,3.884021348,0.01734389,DB0047110052904_,4.054515019,0.753902721,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,139724,DB00999,10052904,154,21276,56,12183,0.003125535,1.574676417,1.151660608,2.180022675,0.01399092,DB0099910052904_,4.269346754,0.454049802,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,139726,DB00213,10022052,51,18844,13,13408,0.000505302,2.791248619,1.495533785,5.596675601,0.003115246,DB0021310022052_,5.771447009,1.026489029,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,139727,DB00213,10037153,169,18726,60,13361,1.48965018272126e-06,2.009638807,1.487288034,2.747508945,2.04627410780394e-05,DB0021310037153_,10.79690483,0.697955008,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,139731,DB00635,10003504,20,33033,36,23758,0.000965711,0.399571324,0.219120114,0.709200057,0.005352957,DB0063510003504_,5.230106069,-0.917362996,NA,10003504,Aspiration,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,139737,DB01076,10060933,98,25649,74,25509,0.078934235,1.317084722,0.963509548,1.806913368,0.176555085,DB0107610060933_,1.734122354,0.27542075,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,139747,DB01020,10000081,22,1791,35,1843,0.141292964,0.646899814,0.359990839,1.139144939,0.27169856,DB0102010000081_,1.303062063,-0.435563844,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,isosorbide mononitrate,DB01020
,139749,DB01225,10008190,53,4991,51,4589,0.843958716,0.955499363,0.636695113,1.435187165,0.921048571,DB0122510008190_,0.082242506,-0.045521182,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,enoxaparin,DB01225
,139752,DB14512,10021097,38,4806,19,2393,1,0.995838541,0.558651055,1.832958733,1,DB1451210021097_,0,-0.004170142,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,mometasone furoate,DB14512
,139763,DB01036,10013709,104,1397,25,397,0.510136468,1.182087246,0.745705088,1.937518982,0.670606515,DB0103610013709_,0.399572729,0.167281729,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tolterodine,DB01036
,139776,DB14512,10011906,69,4775,57,2355,0.005444655,0.59705391,0.412753971,0.866598311,0.021896079,DB1451210011906_,3.821447718,-0.515747869,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,139778,DB00441,10018884,40,2234,28,1866,0.539806918,1.193196395,0.714912131,2.016658327,0.69553063,DB0044110018884_,0.363080228,0.176635753,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,gemcitabine,DB00441
,139783,DB00190,10035664,60,3237,150,4524,0.000117574,0.559076947,0.405915106,0.761850056,0.000916498,DB0019010035664_,6.994950489,-0.581468164,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,carbidopa,DB00190
,139784,DB00661,10035664,77,3451,38,1557,0.683885038,0.914239447,0.609066501,1.392910064,0.808956803,DB0066110035664_,0.212009759,-0.089662765,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,verapamil,DB00661
,139785,DB00190,10035669,21,3276,58,4616,0.007935988,0.510210453,0.293512971,0.855403699,0.029595318,DB0019010035669_,3.520139097,-0.672931985,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,carbidopa,DB00190
,139786,DB00264,10035669,39,29568,53,24839,0.027296517,0.618173133,0.397891036,0.952957307,0.078659096,DB0026410035669_,2.542632005,-0.48098671,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,metoprolol,DB00264
,139804,DB00530,10000081,41,1767,44,1224,0.056872403,0.645580066,0.408640256,1.017918303,0.137564621,DB0053010000081_,1.983661498,-0.43760604,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,erlotinib,DB00530
,139807,DB00620,10012174,57,4771,29,3103,0.318482634,1.278303239,0.801818053,2.078636096,0.486449883,DB0062010012174_,0.720621398,0.245533604,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,triamcinolone,DB00620
,139811,DB01104,10028391,63,15400,24,7262,0.42119062,1.237802422,0.761773266,2.073524725,0.590248472,DB0110410028391_,0.527211693,0.213337567,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,139815,DB00222,10022437,68,3138,44,3084,0.03560405,1.518752856,1.02077661,2.280260426,0.096703726,DB0022210022437_,2.336103346,0.417889508,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,glimepiride,DB00222
,139824,DB06605,10061256,40,14033,44,12989,0.445665219,0.8414649,0.534041812,1.322439212,0.613539532,DB0660510061256_,0.48851058,-0.172610978,NA,10061256,Ischaemic stroke,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,139827,DB11365,10010305,28,1617,42,1506,0.053651743,0.62100011,0.368701018,1.031586439,0.131859379,DB1136510010305_,2.026019236,-0.476424019,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,sennosides,DB11365
,139850,DB00182,10070863,272,4922,313,2539,2.09107716410658e-20,0.448319011,0.376966626,0.532936684,2.24801485720006e-18,DB0018210070863_,40.63648413,-0.802250221,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,amphetamine,DB00182
,139851,DB00950,10047899,96,4622,32,2024,0.207175282,1.313620837,0.868913521,2.033235663,0.357839551,DB0095010047899_,1.027670574,0.272787322,NA,10047899,Weight increased,10022891,Investigations,Inv,fexofenadine,DB00950
,139880,DB00758,10041349,91,8209,80,9994,0.036996629,1.384805392,1.012641693,1.896869876,0.099580809,DB0075810041349_,2.306785817,0.325559618,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,139893,DB01050,10064355,82,18026,57,9314,0.088687954,0.74335668,0.523215507,1.062354586,0.193080951,DB0105010064355_,1.644645743,-0.296579296,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,139913,DB00722,10017412,68,25335,51,25981,0.09852967,1.367317015,0.936666126,2.006981393,0.208682355,DB0072210017412_,1.566942017,0.312850436,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,lisinopril,DB00722
,139914,DB00999,10017412,61,21369,22,12217,0.067500548,1.585191842,0.958994265,2.71241891,0.156860746,DB0099910017412_,1.852396832,0.460705436,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,139926,DB00285,10020937,117,10834,29,3689,0.150946382,1.373697805,0.906557341,2.144202719,0.285214984,DB0028510020937_,1.254512054,0.317506232,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,139927,DB00028,10028596,38,13420,30,5585,0.010808699,0.527140549,0.317700872,0.882032602,0.037885939,DB0002810028596_,3.273175244,-0.640288069,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,human immunoglobulin g,DB00028
,139937,DB00381,10016288,86,29274,100,22787,0.00753399,0.669442422,0.495593909,0.902638478,0.028389642,DB0038110016288_,3.561730917,-0.401310119,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,amlodipine,DB00381
,139939,DB09053,10016288,19,2266,71,3981,0.00266675,0.47019006,0.266843537,0.791396138,0.012281303,DB0905310016288_,4.399677289,-0.754618283,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,ibrutinib,DB09053
,139962,DB00363,10010264,23,4605,33,6855,0.892131221,1.037530133,0.580899059,1.823715902,0.955096007,DB0036310010264_,0.045943412,0.036843017,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,clozapine,DB00363
,139992,DB01050,10061024,38,18070,28,9343,0.154808227,0.701687137,0.419159473,1.187942961,0.290527935,DB0105010061024_,1.236055546,-0.354267649,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,ibuprofen,DB01050
,139996,DB01109,10000636,28,4384,37,4233,0.215814119,0.730721039,0.429881538,1.22926806,0.368367423,DB0110910000636_,0.998674408,-0.313723508,NA,10000636,Activated partial thromboplastin time prolonged,10022891,Investigations,Inv,heparin,DB01109
,140050,DB00497,10065154,88,19179,48,16327,0.012437584,1.560685543,1.085088945,2.268644751,0.042355757,DB0049710065154_,3.161650921,0.445125176,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,oxycodone,DB00497
,140051,DB00787,10065154,39,16961,15,17233,0.00093962,2.641738031,1.423136478,5.159721738,0.005232055,DB0078710065154_,5.252951125,0.971437045,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,acyclovir,DB00787
,140052,DB01039,10065154,34,2939,25,3026,0.238935557,1.400173948,0.808891208,2.454591281,0.396666527,DB0103910065154_,0.924659334,0.336596477,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,fenofibrate,DB01039
,140084,DB00722,10000891,74,25329,122,25910,0.001227054,0.620479699,0.458171752,0.835430704,0.006511832,DB0072210000891_,5.034134412,-0.477262392,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,lisinopril,DB00722
,140114,DB00390,10033425,119,4026,46,3255,1.58616422616803e-05,2.091309088,1.471275257,3.016586425,0.000162543,DB0039010033425_,8.724566844,0.737790228,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,digoxin,DB00390
,140190,DB01050,10005557,83,18025,42,9329,1,1.022794798,0.696833657,1.521239321,1,DB0105010005557_,0,0.022538879,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,ibuprofen,DB01050
,140202,DB01075,10005724,67,19881,19,11078,0.009123062,1.964877708,1.165454757,3.465781785,0.033084947,DB0107510005724_,3.408676887,0.675430008,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,diphenhydramine,DB01075
,140271,DB00497,10038687,30,19237,37,16338,0.14123609,0.688636081,0.410679351,1.14612103,0.27161184,DB0049710038687_,1.303381291,-0.373042333,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,140299,DB00327,10061822,35,6103,20,4242,0.582805237,1.216334634,0.681930962,2.226971033,0.730939768,DB0032710061822_,0.313424219,0.195841938,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,140300,DB00813,10061822,59,10513,34,10134,0.016723448,1.672686396,1.077737163,2.633526571,0.053682094,DB0081310061822_,2.924675787,0.514430954,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,140317,DB00343,10027091,67,8669,46,5049,0.433481365,0.848324464,0.573253821,1.265064814,0.602015876,DB0034310027091_,0.507471462,-0.164492094,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,140331,DB00295,10047513,67,14596,37,9565,0.423262401,1.186612367,0.782107955,1.82554011,0.592141588,DB0029510047513_,0.524009505,0.171102497,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,morphine,DB00295
,140334,DB01039,10011224,56,2917,48,3003,0.374345014,1.201024276,0.799247061,1.810827567,0.54419881,DB0103910011224_,0.608440639,0.183174756,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fenofibrate,DB01039
,140335,DB00678,10022052,41,15558,13,10711,0.012371353,2.171214273,1.139914208,4.418440145,0.042171057,DB0067810022052_,3.166021158,0.775286584,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,140337,DB00335,10022095,41,8425,11,5454,0.00670124,2.412739824,1.216654538,5.209332273,0.025871819,DB0033510022095_,3.654600972,0.880762958,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,140338,DB00678,10022095,49,15550,14,10710,0.002854025,2.410522235,1.308835042,4.73038451,0.012984518,DB0067810022095_,4.343997568,0.879843419,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,140356,DB01212,10043554,35,1984,43,1898,0.303895429,0.778722913,0.481530968,1.25166319,0.47047097,DB0121210043554_,0.754021023,-0.250099993,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,ceftriaxone,DB01212
,140363,DB00650,10003239,35,2096,27,1987,0.444913398,1.228821362,0.719673547,2.119260572,0.612964483,DB0065010003239_,0.489448284,0.206055468,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,leucovorin,DB00650
,140370,DB00482,10033557,57,8202,17,3054,0.511881151,1.248425407,0.714569161,2.292984597,0.672160972,DB0048210033557_,0.397257426,0.221883083,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,celecoxib,DB00482
,140385,DB00047,10022067,44,9241,42,8476,0.913955109,0.960882435,0.614413282,1.504613685,0.961512267,DB0004710022067_,0.039247956,-0.039903213,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,140391,DB06703,10015150,71,704,29,382,0.228715877,1.328151147,0.834238394,2.161678942,0.384312269,DB0670310015150_,0.956299856,0.28378786,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,gadobutrol,DB06703
,140395,DB00341,10022437,194,11211,62,5006,0.024094691,1.397203292,1.042443225,1.89481385,0.071457627,DB0034110022437_,2.63865064,0.33447259,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,cetirizine,DB00341
,140396,DB01060,10022437,115,8472,62,5019,0.584268993,1.098853969,0.798336872,1.524746552,0.732059512,DB0106010022437_,0.311893468,0.094267791,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,amoxicillin,DB01060
,140398,DB01281,10022095,88,8844,6,1792,0.005024244,2.971614633,1.309094061,8.329582673,0.020543245,DB0128110022095_,3.885223121,1.089105453,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,140405,DB00331,10006002,75,24871,53,20699,0.375376455,1.177713786,0.817109595,1.708023685,0.545260984,DB0033110006002_,0.60649073,0.16357509,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,140406,DB00695,10064684,64,27985,16,20512,3.48609738634273e-05,2.931745816,1.674571247,5.435632404,0.000323617,DB0069510064684_,8.035950754,1.075598087,female,10064684,Device dislocation,10077536,Product issues,Prod,furosemide,DB00695
,140407,DB08932,10064684,179,19264,44,6553,0.053389638,1.383824439,0.988953027,1.973473121,0.13135645,DB0893210064684_,2.029840661,0.324850999,NA,10064684,Device dislocation,10077536,Product issues,Prod,macitentan,DB08932
,140417,DB08904,10013700,173,11437,29,3530,0.001458554,1.841099001,1.234778937,2.836239558,0.007514678,DB0890410013700_,4.890897143,0.610362677,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,certolizumab pegol,DB08904
,140418,DB00588,10054112,224,16300,142,8326,0.051361143,0.805789358,0.648956255,1.003167073,0.127571713,DB0058810054112_,2.059076615,-0.215932913,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,fluticasone propionate,DB00588
,140420,DB01222,10054112,138,9136,91,5314,0.369620233,0.882081418,0.670532575,1.164996723,0.539238931,DB0122210054112_,0.61759652,-0.125470917,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,budesonide,DB01222
,140421,DB01409,10054112,83,5948,47,3919,0.4704889,1.163493527,0.801992964,1.705456871,0.63675827,DB0140910054112_,0.451365177,0.151427141,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,tiotropium,DB01409
,140424,DB00381,10001052,37,29323,26,22861,0.705332408,1.109503289,0.653768147,1.908723508,0.823436036,DB0038110001052_,0.194269406,0.103912428,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,140426,DB00695,10001052,46,28003,27,20501,0.407293515,1.247275525,0.75895021,2.08738524,0.576831813,DB0069510001052_,0.55020454,0.220961593,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,140433,DB01212,10002198,37,1982,46,1895,0.267463164,0.769094629,0.482709159,1.21805001,0.429775601,DB0121210002198_,0.844492066,-0.262541262,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,ceftriaxone,DB01212
,140437,DB01069,10000060,46,6654,13,2382,0.55333846,1.266654659,0.671433106,2.560410942,0.70697037,DB0106910000060_,0.346766524,0.236379298,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,promethazine,DB01069
,140443,DB00046,10022437,41,5418,47,4645,0.197559618,0.747907732,0.478807307,1.164117593,0.346040352,DB0004610022437_,1.061199886,-0.290475661,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,insulin lispro,DB00046
,140444,DB00047,10022437,92,9193,78,8440,0.643747633,1.082906082,0.790910368,1.485733287,0.780052855,DB0004710022437_,0.248393598,0.079648244,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,insulin glargine,DB00047
,140453,DB01098,10047899,135,8014,64,7145,2.24510155539302e-05,1.880563432,1.384102372,2.577899914,0.000220484,DB0109810047899_,8.419686245,0.63157143,NA,10047899,Weight increased,10022891,Investigations,Inv,rosuvastatin,DB01098
,140467,DB00381,10019196,80,29280,41,22846,0.02784008,1.522443242,1.031863029,2.276967286,0.079866467,DB0038110019196_,2.527399198,0.420316441,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,140470,DB00829,10047340,57,7995,19,4435,0.054839886,1.66410223,0.973761406,2.966389738,0.134052488,DB0082910047340_,2.009523852,0.509285777,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,diazepam,DB00829
,140483,DB00007,10061818,15,1932,63,4389,0.034577708,0.540935664,0.285289187,0.964032634,0.09458089,DB0000710061818_,2.358299828,-0.614454928,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,leuprolide,DB00007
,140485,DB01050,10061818,150,17958,65,9306,0.248102139,1.195835886,0.88712198,1.627419383,0.407474083,DB0105010061818_,0.897777949,0.178845427,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,140486,DB06643,10061818,133,52288,48,7467,3.80768271660773e-07,0.395716031,0.282204311,0.56305242,6.04925598102353e-06,DB0664310061818_,12.01557527,-0.927058418,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,140487,DB00203,10001949,44,13834,28,8910,1,1.012102485,0.615662378,1.689614219,1,DB0020310001949_,0,0.012029835,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,140515,DB00051,10007559,79,25652,55,11365,0.011233491,0.636382685,0.445057769,0.915578606,0.039075273,DB0005110007559_,3.242265408,-0.45195519,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,adalimumab,DB00051
,140518,DB01281,10007559,33,8899,19,1779,0.000535238,0.347288142,0.191254804,0.647928124,0.003264032,DB0128110007559_,5.724792007,-1.057600463,male,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,abatacept,DB01281
,140523,DB08877,10033425,68,3221,41,3188,0.012077917,1.641411946,1.09433294,2.489005995,0.041347753,DB0887710033425_,3.185737195,0.495556814,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ruxolitinib,DB08877
,140529,DB00399,10031252,20,6972,30,4968,0.009561386,0.475067265,0.255392775,0.8657935,0.034356944,DB0039910031252_,3.370951133,-0.744298875,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,zoledronic acid,DB00399
,140530,DB00480,10031252,56,67372,92,67570,0.003853105,0.61049039,0.429837951,0.860382661,0.016548835,DB0048010031252_,4.101439602,-0.493492727,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,140544,DB00433,10014625,35,7621,26,5994,0.897436275,1.058772722,0.618577852,1.833686326,0.956338178,DB0043310014625_,0.044643686,0.057110428,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,140545,DB00904,10014625,111,22958,80,14376,0.37110663,0.868841393,0.645439201,1.174054534,0.540717172,DB0090410014625_,0.614858925,-0.140594687,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,140563,DB00788,10029354,44,9312,27,5034,0.619162886,0.880978435,0.532824714,1.481468412,0.759996182,DB0078810029354_,0.27444187,-0.126722131,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,naproxen,DB00788
,140565,DB01050,10058080,40,18068,29,9342,0.164247802,0.713149329,0.430947942,1.193624646,0.303082134,DB0105010058080_,1.193751439,-0.338064443,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,140566,DB00091,10029331,47,5463,27,2643,0.533565214,0.842201177,0.512554342,1.409658483,0.690262052,DB0009110029331_,0.370683968,-0.171736366,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,cyclosporine,DB00091
,140567,DB00193,10029331,223,19097,109,8593,0.474650472,0.920577851,0.727776806,1.170202762,0.640329894,DB0019310029331_,0.445771777,-0.082753707,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,140610,DB01590,10042674,34,4704,20,2847,1,1.028887976,0.574260847,1.890204552,1,DB0159010042674_,0,0.028478584,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,140624,DB00186,10038678,58,16843,36,9972,0.831244001,0.953883862,0.618210594,1.489705023,0.911753388,DB0018610038678_,0.092385734,-0.047213353,NA,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,140631,DB00186,10039897,65,16836,82,9926,4.72128504783214e-06,0.467348435,0.331882864,0.655808146,5.62679562377093e-05,DB0018610039897_,9.785385346,-0.760680186,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,140638,DB00047,10048294,43,9242,54,8464,0.127229308,0.729280388,0.476388651,1.110429323,0.251757622,DB0004710048294_,1.379288473,-0.315697001,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,insulin glargine,DB00047
,140642,DB01270,10013709,68,1190,41,928,0.234520759,1.293231659,0.856202924,1.974111161,0.391411228,DB0127010013709_,0.937996539,0.257144248,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ranibizumab,DB01270
,140652,DB01075,10060933,32,19916,18,11079,1,0.988950696,0.538303422,1.872177614,1,DB0107510060933_,0,-0.011110801,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,140655,DB01075,10018836,39,19909,25,11072,0.602464697,0.867572928,0.511656063,1.496598894,0.746381968,DB0107510018836_,0.292517788,-0.142055704,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,140663,DB00368,10021097,71,589,84,714,0.932028978,1.024608614,0.722145837,1.450644762,0.97294949,DB0036810021097_,0.02742311,0.0243107,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,norepinephrine,DB00368
,140714,DB00421,10013946,76,8827,23,5229,0.004557403,1.957366485,1.21224527,3.2750239,0.018961826,DB0042110013946_,3.965327498,0.67159994,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,140716,DB00829,10013946,49,8003,13,4441,0.016232367,2.09149976,1.115899679,4.207181491,0.052431156,DB0082910013946_,2.948254291,0.737881397,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,diazepam,DB00829
,140718,DB14500,10013946,41,7768,14,4059,0.200138622,1.530210522,0.816001875,3.043010579,0.349167654,DB1450010013946_,1.052203088,0.425405322,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,140719,DB00421,10027599,83,8820,12,5240,1.57092948389487e-07,4.108905421,2.228551152,8.281881073,2.73456168769381e-06,DB0042110027599_,12.8095394,1.413156672,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,140721,DB00956,10027599,72,5742,11,3456,1.71620289955807e-06,3.939130651,2.072016484,8.252111894,2.31475014441127e-05,DB0095610027599_,10.67362371,1.370960052,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,140735,DB01432,10053762,37,1254,23,647,0.49180166,0.830097941,0.47572671,1.476645321,0.654875352,DB0143210053762_,0.423310364,-0.186211583,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cholestyramine,DB01432
,140778,DB00285,10069327,39,10912,14,3704,0.874483876,0.945589884,0.501604347,1.887647547,0.945626193,DB0028510069327_,0.055907933,-0.055946331,NA,10069327,Product quality issue,10077536,Product issues,Prod,venlafaxine,DB00285
,140796,DB00704,10000087,67,4289,95,5099,0.301158746,0.838471643,0.602302931,1.161680212,0.467418006,DB0070410000087_,0.760531333,-0.176174517,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,naltrexone,DB00704
,140797,DB00704,10037660,45,4311,52,5142,0.918535125,1.032206613,0.675382896,1.572200643,0.963993363,DB0070410037660_,0.036670869,0.031698854,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,140804,DB08935,10029354,43,489,45,768,0.07133204,1.50023705,0.94879255,2.369669391,0.163587896,DB0893510029354_,1.810404841,0.405623129,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,obinutuzumab,DB08935
,140805,DB08935,10043554,23,509,32,781,0.778715939,1.102753813,0.608649123,1.969590638,0.879365569,DB0893510043554_,0.128554576,0.097810517,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,obinutuzumab,DB08935
,140812,DB00448,10042674,46,5099,13,3111,0.014543277,2.158702576,1.144544281,4.362579301,0.048078234,DB0044810042674_,3.034925721,0.769507382,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,140813,DB00787,10042674,88,16912,70,17178,0.130379845,1.276903269,0.92159911,1.775010296,0.256274759,DB0078710042674_,1.361505132,0.244437825,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,140814,DB00836,10042674,31,5504,20,4055,0.672822448,1.141895453,0.629443173,2.117254228,0.801411037,DB0083610042674_,0.221381309,0.13268956,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,140815,DB01234,10042674,168,31457,118,32770,0.001082787,1.483136423,1.164418332,1.894220732,0.005882205,DB0123410042674_,5.135823644,0.39415905,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,140816,DB00424,10053762,35,1159,21,407,0.063713222,0.585491681,0.327074913,1.071677515,0.150150359,DB0042410053762_,1.896118091,-0.535303305,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,hyoscyamine,DB00424
,140820,DB00736,10060800,59,10532,12,5541,0.001558145,2.586579652,1.374248609,5.29118783,0.007932568,DB0073610060800_,4.836778497,0.950336405,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,esomeprazole,DB00736
,140837,DB00279,10053762,41,1196,11,205,0.230141018,0.639100443,0.316152438,1.401980427,0.386114551,DB0027910053762_,0.95162119,-0.447693649,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,liothyronine,DB00279
,140843,DB01075,10047571,95,19853,28,11069,0.00243026,1.891644215,1.228937491,2.997501721,0.011405151,DB0107510047571_,4.473690197,0.637446406,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,diphenhydramine,DB01075
,140847,DB00514,10046571,38,2128,17,1519,0.12915387,1.595393932,0.875100486,3.026380442,0.254408347,DB0051410046571_,1.368814638,0.467120685,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,dextromethorphan,DB00514
,140855,DB00169,10019194,63,38628,14,18161,0.009730705,2.115655915,1.172196377,4.090117262,0.034826098,DB0016910019194_,3.357388217,0.74936489,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,140859,DB04844,10012378,44,632,27,442,0.621063721,1.13955086,0.678503123,1.945007422,0.761482411,DB0484410012378_,0.272488205,0.130634202,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,tetrabenazine,DB04844
,140860,DB00287,10015946,67,1334,40,777,0.918377396,0.975615254,0.642787356,1.497124147,0.963904799,DB0028710015946_,0.036762745,-0.024686977,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,travoprost,DB00287
,140868,DB00153,10060800,43,7380,15,3424,0.3969923,1.330026446,0.723163435,2.58102907,0.566623729,DB0015310060800_,0.568059813,0.285198826,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,ergocalciferol,DB00153
,140872,DB00213,10003119,31,18864,34,13387,0.079256283,0.647064847,0.384368266,1.085548829,0.177170691,DB0021310003119_,1.730641655,-0.435308762,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,pantoprazole,DB00213
,140878,DB00887,10010305,38,2303,33,1782,0.631590476,0.891037763,0.541685655,1.472449965,0.770436034,DB0088710010305_,0.260798646,-0.115368469,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,bumetanide,DB00887
,140894,DB00213,10050256,40,18855,19,13402,0.185572228,1.49638668,0.846210245,2.736790847,0.330909129,DB0021310050256_,1.105911476,0.403053322,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,140898,DB00996,10050256,76,38877,45,22380,0.924763576,0.97221041,0.663541345,1.439194497,0.967593918,DB0099610050256_,0.032942786,-0.028183027,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,140900,DB00370,10002034,62,4479,47,3616,0.771849171,1.06498763,0.715279926,1.59480863,0.875126405,DB0037010002034_,0.13338694,0.062963184,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,mirtazapine,DB00370
,140901,DB08816,10002034,20,1131,31,1871,0.884361223,1.067259134,0.573583238,1.943737971,0.951843037,DB0881610002034_,0.049355134,0.065093805,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ticagrelor,DB08816
,140934,DB01076,10029366,48,25699,57,25526,0.380369266,0.836440434,0.557390246,1.250499421,0.55042976,DB0107610029366_,0.597055925,-0.17859997,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,140935,DB00448,10047942,40,5105,20,3104,0.507105434,1.215996435,0.692828932,2.19993167,0.667732008,DB0044810047942_,0.403868372,0.195563852,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,lansoprazole,DB00448
,140938,DB00540,10011906,75,2408,63,1028,0.000145662,0.508314164,0.355718082,0.728321455,0.00109926,DB0054010011906_,6.813117732,-0.67665559,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,nortriptyline,DB00540
,140939,DB00555,10011906,195,6852,125,3361,0.025439234,0.765249071,0.60577665,0.969513289,0.074466314,DB0055510011906_,2.597408412,-0.267553915,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,140943,DB05259,10046571,198,11072,40,2688,0.322247192,1.201717465,0.849491914,1.737758515,0.49060293,DB0525910046571_,0.712120175,0.183751755,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,glatiramer,DB05259
,140947,DB01067,10028334,55,4306,37,4786,0.020610778,1.652082709,1.067138205,2.583777589,0.063285358,DB0106710028334_,2.760101287,0.50203674,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,glipizide,DB01067
,140952,DB06724,10028596,32,7897,24,3895,0.119811628,0.657642828,0.37478176,1.168577829,0.241118492,DB0672410028596_,1.422466796,-0.41909331,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,calcium carbonate,DB06724
,140958,DB14513,10008190,57,7120,34,3530,0.433886329,0.831199855,0.533130921,1.313640166,0.602435274,DB1451310008190_,0.506775049,-0.184885014,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,140964,DB01068,10016275,39,13724,12,6828,0.179676896,1.616913775,0.828771814,3.394179731,0.323452145,DB0106810016275_,1.128704104,0.480519255,NA,10016275,Fear,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,140967,DB00165,10022437,50,2095,19,1347,0.06071773,1.691760153,0.974898561,3.052663052,0.144725961,DB0016510022437_,1.932913246,0.525769498,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,pyridoxine,DB00165
,140973,DB01175,10055798,40,10684,23,4869,0.414109662,0.792610101,0.462590252,1.388409575,0.583373393,DB0117510055798_,0.538927829,-0.232423854,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,escitalopram,DB01175
,140977,DB00619,10001760,73,2826,9,2485,5.92766544720726e-12,7.130417571,3.547562288,16.24143386,2.35716620695678e-10,DB0061910001760_,22.16839079,1.964369798,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,imatinib,DB00619
,140988,DB00788,10005750,84,9272,39,5022,0.449501934,1.166558899,0.787553176,1.75499633,0.617092332,DB0078810005750_,0.48273662,0.154058303,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,naproxen,DB00788
,141003,DB00281,10020993,37,11421,14,5657,0.457499889,1.309072035,0.690531133,2.62352803,0.62484137,DB0028110020993_,0.47025747,0.269318516,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,lidocaine,DB00281
,141005,DB01136,10020993,62,9822,81,11034,0.400981635,0.859890331,0.606852241,1.213350047,0.570798932,DB0113610020993_,0.560718265,-0.150950419,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,carvedilol,DB01136
,141040,DB00321,10007617,156,7291,60,2790,1,0.994925704,0.731657308,1.367902532,1,DB0032110007617_,0,-0.005087214,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,amitriptyline,DB00321
,141066,DB00193,10046555,23,19297,31,8671,8.34202835440174e-05,0.33339918,0.185521683,0.591021705,0.000683355,DB0019310046555_,7.288495551,-1.098414769,male,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,tramadol,DB00193
,141076,DB05676,10008531,99,47030,32,25297,0.012945662,1.664088042,1.106673523,2.563560329,0.043730703,DB0567610008531_,3.129704827,0.509277251,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,141078,DB00222,10012174,55,3151,53,3075,1,1.012705523,0.679285035,1.510911897,1,DB0022210012174_,0,0.012625486,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,glimepiride,DB00222
,141082,DB00722,10038540,25,25378,53,25979,0.002136553,0.482877714,0.287417982,0.791133734,0.010272413,DB0072210038540_,4.578293282,-0.727991838,NA,10038540,Renal tubular necrosis,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,141085,DB00338,10000496,52,33622,24,22248,0.15979102,1.433694612,0.867768011,2.432671562,0.297163362,DB0033810000496_,1.213473253,0.360254757,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,141106,DB00153,10006002,73,7350,10,3429,4.37860126580934e-05,3.405226115,1.747545135,7.406209867,0.000394893,DB0015310006002_,7.836895982,1.225311344,female,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,141108,DB00338,10021519,77,33597,32,22240,0.030698157,1.592836184,1.041645997,2.487635093,0.086258065,DB0033810021519_,2.450411726,0.465516191,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,141126,DB01075,10050819,49,19899,19,11078,0.205721915,1.435713393,0.829489692,2.583824283,0.356113177,DB0107510050819_,1.032506685,0.361661864,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,141133,DB06674,10040753,50,4456,9,1481,0.096108664,1.846393153,0.896063305,4.281012662,0.204933579,DB0667410040753_,1.585069358,0.613234089,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,golimumab,DB06674
,141134,DB00051,10046306,160,25571,42,11378,0.001687471,1.695053307,1.199162766,2.443234326,0.008459885,DB0005110046306_,4.772419756,0.52771419,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,adalimumab,DB00051
,141163,DB01075,10028372,114,19834,82,11015,0.085220449,0.772110225,0.575665034,1.039415005,0.18710487,DB0107510028372_,1.676086019,-0.258627961,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,141169,DB00072,10047895,66,3657,6,329,1,0.989610715,0.426687842,2.815043945,1,DB0007210047895_,0,-0.01044363,NA,10047895,Weight decreased,10022891,Investigations,Inv,trastuzumab,DB00072
,141175,DB01234,10049438,54,31571,63,32825,0.579025497,0.891190509,0.607699136,1.303045164,0.727772694,DB0123410049438_,0.317766513,-0.115197059,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,141184,DB01234,10059282,35,31590,28,32860,0.315346453,1.300243597,0.768285088,2.21941535,0.482950621,DB0123410059282_,0.727840864,0.262551629,NA,10059282,Metastases to central nervous system,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,141196,DB00904,10074170,51,23018,29,14427,0.730870462,1.102265361,0.685176895,1.804476434,0.843454003,DB0090410074170_,0.170249909,0.097367481,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,ondansetron,DB00904
,141197,DB01075,10074170,36,19912,15,11082,0.383116385,1.335705177,0.712891609,2.627127137,0.553186891,DB0107510074170_,0.592059376,0.289459375,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,141239,DB00635,10019744,23,33030,44,23750,9.81273286048356e-05,0.375868778,0.216606223,0.636274657,0.000784094,DB0063510019744_,7.150981794,-0.978515192,NA,10019744,Hepatitis C,10021881,Infections and infestations,Infec,prednisone,DB00635
,141251,DB00213,10019974,92,18803,37,13384,0.003014912,1.769848715,1.195398504,2.669073346,0.013567361,DB0021310019974_,4.300088261,0.570894071,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,141266,DB00531,10013950,40,7212,36,6480,1,0.998336199,0.619509173,1.614037719,1,DB0053110013950_,0,-0.001665187,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,cyclophosphamide,DB00531
,141274,DB01233,10025482,103,3318,38,1688,0.103409088,1.378872194,0.93716208,2.066542525,0.216125939,DB0123310025482_,1.531893991,0.321265914,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,141315,DB00635,10041660,29,33024,40,23754,0.007204485,0.521506391,0.311720641,0.862718471,0.027391523,DB0063510041660_,3.597521697,-0.65103375,NA,10041660,Splenomegaly,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,141329,DB01101,10016173,64,7525,32,3876,1,1.030164452,0.662596585,1.630729597,1,DB0110110016173_,0,0.029718452,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,capecitabine,DB01101
,141344,DB01073,10020983,62,1003,101,1549,0.80411222,0.948038856,0.672623135,1.327588009,0.894066865,DB0107310020983_,0.111974713,-0.05335979,NA,10020983,Hypogammaglobulinaemia,10021428,Immune system disorders,Immun,fludarabine,DB01073
,141355,DB00537,10022437,104,7453,50,4248,0.353841614,1.185559544,0.836335892,1.699837464,0.52367483,DB0053710022437_,0.64688434,0.170214852,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ciprofloxacin,DB00537
,141388,DB00958,10010305,49,4545,29,2556,0.81368571,0.950230271,0.586798824,1.564135602,0.899948619,DB0095810010305_,0.105417608,-0.051050933,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,carboplatin,DB00958
,141389,DB00112,10012378,62,5871,47,4044,0.62545105,0.908652012,0.610572185,1.360133341,0.765077292,DB0011210012378_,0.267778415,-0.095793083,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,bevacizumab,DB00112
,141396,DB01234,10020765,41,31584,63,32825,0.061667421,0.676371606,0.444796111,1.01847363,0.146498094,DB0123410020765_,1.920742858,-0.391012642,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,141398,DB01234,10061309,62,31563,57,32831,0.521530382,1.13141402,0.776518243,1.651139602,0.680335795,DB0123410061309_,0.385168787,0.123468196,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,141404,DB01101,10012378,51,7538,10,3898,0.002723023,2.637090163,1.321912145,5.833094135,0.012489033,DB0110110012378_,4.382904347,0.969676098,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,capecitabine,DB01101
,141405,DB01229,10012378,66,5675,6,2703,2.73877642313505e-06,5.239033652,2.278798633,14.80994072,3.4961146652257e-05,DB0122910012378_,10.26127321,1.656137064,female,10012378,Depression,10037175,Psychiatric disorders,Psych,paclitaxel,DB01229
,141422,DB01240,10007882,81,5670,30,1546,0.16233077,0.736224159,0.476826693,1.164334573,0.300504563,DB0124010007882_,1.20229234,-0.306220642,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,141439,DB00559,10043071,61,9598,19,3287,0.797629583,1.099491168,0.646813758,1.952000565,0.890622272,DB0055910043071_,0.115834878,0.094847498,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,bosentan,DB00559
,141440,DB09140,10043071,58,3683,27,1771,1,1.032920824,0.641136903,1.70285504,1,DB0914010043071_,0,0.032390541,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,oxygen,DB09140
,141445,DB00316,10021113,77,65397,6,36947,1.43096862297589e-09,7.250856974,3.183030535,20.36618962,3.84394586151469e-08,DB0031610021113_,17.07418134,1.981119665,female,10021113,Hypothermia,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,141514,DB00112,10028411,51,5882,18,4073,0.013535535,1.961816175,1.124902398,3.573783397,0.045305176,DB0011210028411_,3.094334001,0.673870664,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,bevacizumab,DB00112
,141515,DB00958,10028411,41,4553,9,2576,0.007332953,2.577150596,1.231286441,6.039769175,0.027783306,DB0095810028411_,3.583319959,0.946684369,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,carboplatin,DB00958
,141516,DB01060,10001760,85,8502,11,5070,2.66407730941457e-08,4.607612032,2.446411993,9.587131013,5.43674472654985e-07,DB0106010001760_,14.42491517,1.527709725,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,amoxicillin,DB01060
,141518,DB11365,10002034,46,1599,48,1500,0.675473422,0.899029854,0.582895055,1.385221974,0.8032946,DB1136510002034_,0.219033759,-0.106439037,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,sennosides,DB11365
,141520,DB01060,10016173,190,8397,97,4984,0.241315449,1.162635458,0.903218671,1.504425775,0.399427795,DB0106010016173_,0.917722269,0.150689375,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,amoxicillin,DB01060
,141521,DB11365,10016173,66,1579,66,1482,0.723137699,0.938617237,0.651930856,1.351344148,0.837158089,DB1136510016173_,0.177742351,-0.063347511,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sennosides,DB11365
,141523,DB01060,10020937,84,8503,41,5040,0.352622134,1.214318789,0.824924081,1.81290964,0.52238476,DB0106010020937_,0.649350874,0.194183252,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,amoxicillin,DB01060
,141524,DB01229,10020937,84,5657,15,2694,0.000192687,2.666602674,1.524686301,4.984239762,0.001396221,DB0122910020937_,6.573986138,0.980805256,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,paclitaxel,DB01229
,141527,DB11365,10025482,58,1587,30,1518,0.006667753,1.848920867,1.162947385,2.993889545,0.025777597,DB1136510025482_,3.658249489,0.614602154,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sennosides,DB11365
,141543,DB01060,10029354,39,8548,38,5043,0.032722043,0.605538417,0.376728788,0.973989473,0.090670347,DB0106010029354_,2.400524914,-0.501637271,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,amoxicillin,DB01060
,141544,DB11365,10029354,40,1605,40,1508,0.821257005,0.939552743,0.587220426,1.503369486,0.904741207,DB1136510029354_,0.100106335,-0.062351322,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,sennosides,DB11365
,141552,DB01060,10039101,37,8550,23,5058,0.893734797,0.951683669,0.549970564,1.679632818,0.955748455,DB0106010039101_,0.045260523,-0.049522579,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amoxicillin,DB01060
,141586,DB00073,10022000,32,7374,22,6385,0.41631549,1.259439699,0.708607889,2.277513596,0.585576646,DB0007310022000_,0.535158198,0.230666939,NA,10022000,Influenza,10021881,Infections and infestations,Infec,rituximab,DB00073
,141630,DB01234,10008796,33,31592,34,32854,1,1.009360743,0.605779799,1.680101764,1,DB0123410008796_,0,0.009317203,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,dexamethasone,DB01234
,141632,DB00454,10013968,34,1933,17,584,0.095919114,0.604375647,0.325621079,1.16248567,0.204646391,DB0045410013968_,1.58647171,-0.503559342,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,meperidine,DB00454
,141636,DB00788,10015150,104,9252,27,5034,0.00042832,2.095691177,1.35926314,3.334579143,0.002713522,DB0078810015150_,5.909507741,0.739883417,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,naproxen,DB00788
,141646,DB00863,10016334,44,10629,12,5828,0.034729514,2.010397873,1.042733453,4.184965932,0.094912172,DB0086310016334_,2.354803324,0.698332649,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,141651,DB01234,10016334,91,31534,53,32835,0.000787646,1.78778967,1.260050003,2.559023865,0.004515929,DB0123410016334_,5.400144412,0.580980036,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,141677,DB00158,10029410,43,16772,17,8087,0.581437321,1.219579879,0.680765632,2.282514456,0.729765132,DB0015810029410_,0.315032534,0.198506438,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,141680,DB00682,10029410,37,19422,19,16345,0.081960633,1.638823345,0.918195026,3.018189967,0.181632652,DB0068210029410_,1.705769028,0.493978512,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,141681,DB00863,10029410,39,10634,19,5821,0.783531904,1.123584616,0.633163675,2.060681753,0.882171087,DB0086310029410_,0.125369266,0.116524124,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,141707,DB01234,10043224,45,31580,20,32868,0.001144513,2.34174575,1.35436209,4.18752539,0.006160238,DB0123410043224_,5.089639853,0.850896698,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,141728,DB11365,10048959,35,1610,30,1518,0.80223599,1.099947928,0.652467311,1.864774428,0.893015415,DB1136510048959_,0.113151436,0.095262841,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sennosides,DB11365
,141729,DB00863,10051055,43,10630,48,5792,0.000862527,0.488126711,0.315384335,0.753477787,0.004876647,DB0086310051055_,5.323297363,-0.717180254,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,ranitidine,DB00863
,141752,DB11365,10061818,53,1592,42,1506,0.406690712,1.193669288,0.77602977,1.846232992,0.576242002,DB1136510061818_,0.551227564,0.177031999,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,sennosides,DB11365
,141768,DB00563,10017553,36,46610,18,15330,0.15560268,0.657803963,0.363771803,1.230851077,0.291570796,DB0056310017553_,1.232472436,-0.418848321,NA,10017553,Furuncle,10021881,Infections and infestations,Infec,methotrexate,DB00563
,141770,DB00005,10061822,730,127352,140,42279,4.37329560519702e-10,1.730984055,1.442316546,2.090107317,1.29450534890319e-08,DB0000510061822_,18.16255209,0.548690065,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,141771,DB00563,10061822,1726,44920,366,14982,5.96663888755452e-16,1.57277666,1.402083642,1.768166002,4.08419539477527e-14,DB0056310061822_,30.82906656,0.45284263,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,141781,DB01069,10028596,32,6668,22,2373,0.019858873,0.517656212,0.290931131,0.93714896,0.061407033,DB0106910028596_,2.790230904,-0.658443941,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,promethazine,DB01069
,141785,DB00776,10035664,35,1870,24,1315,1,1.025506466,0.589777636,1.811148692,1,DB0077610035664_,0,0.025186604,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,oxcarbazepine,DB00776
,141828,DB00863,10035598,62,10611,33,5807,1,1.028189048,0.662662839,1.621645127,1,DB0086310035598_,0,0.027799049,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,141830,DB01101,10037087,95,7494,30,3878,0.017503254,1.638624003,1.074639397,2.564619175,0.055668585,DB0110110037087_,2.888339289,0.493856867,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,capecitabine,DB01101
,141852,DB13867,10002855,77,4473,26,2528,0.022769017,1.673656706,1.057415573,2.728448499,0.068343453,DB1386710002855_,2.683209505,0.515010877,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,fluticasone,DB13867
,141853,DB13867,10003239,112,4438,45,2509,0.063908537,1.407015859,0.98342479,2.042753607,0.150499659,DB1386710003239_,1.893794458,0.34147105,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone,DB13867
,141860,DB00999,10013946,174,21256,69,12170,0.009052077,1.443791993,1.085400501,1.93872872,0.032879686,DB0099910013946_,3.414900246,0.367272981,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,141864,DB13867,10017885,38,4512,19,2535,0.782027414,1.123669007,0.630346006,2.068027538,0.881268621,DB1386710017885_,0.126392795,0.11659923,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,fluticasone,DB13867
,141866,DB13867,10021789,65,4485,21,2533,0.023975526,1.747975843,1.051741799,3.0183204,0.071192578,DB1386710021789_,2.642366701,0.558458457,NA,10021789,Infection,10021881,Infections and infestations,Infec,fluticasone,DB13867
,141884,DB00722,10042361,15,25388,46,25986,9.38837174140494e-05,0.33374912,0.173039422,0.608977427,0.00075593,DB0072210042361_,7.187561768,-1.097365706,male,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,141888,DB00999,10042609,102,21328,39,12200,0.034918768,1.49602988,1.024252775,2.22465667,0.095277563,DB0099910042609_,2.350960927,0.402814852,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,hydrochlorothiazide,DB00999
,141905,DB00999,10048865,55,21375,31,12208,1,1.013303027,0.640613359,1.629267461,1,DB0099910048865_,0,0.013215319,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,hydrochlorothiazide,DB00999
,141939,DB00788,10008190,59,9297,38,5023,0.395231781,0.838878635,0.547851282,1.298340084,0.564978732,DB0078810008190_,0.570967192,-0.175689237,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,141940,DB00956,10008190,43,5771,32,3435,0.340160642,0.799854696,0.493413797,1.308763032,0.50933507,DB0095610008190_,0.674649189,-0.223325198,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,141944,DB00425,10027599,124,12571,17,7467,3.08800472871996e-11,4.332364376,2.596398079,7.681127442,1.09295292996977e-09,DB0042510027599_,20.63438269,1.466113438,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,141947,DB00472,10028836,57,10702,6,4306,0.000383333,3.8223838,1.650225184,10.85585638,0.002475047,DB0047210028836_,6.001495818,1.340874259,female,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fluoxetine,DB00472
,141951,DB00956,10028836,37,5777,14,3453,0.149794771,1.579602139,0.832632748,3.167855468,0.283656321,DB0095610028836_,1.25999191,0.457173004,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocodone,DB00956
,141991,DB00635,10005956,50,33003,23,23771,0.075817913,1.565785148,0.937534875,2.689127104,0.171183532,DB0063510005956_,1.765019012,0.44838739,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,141996,DB00950,10016173,131,4587,56,2000,0.935884684,1.019972355,0.736901994,1.427348363,0.976044157,DB0095010016173_,0.024247451,0.019775524,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,fexofenadine,DB00950
,141997,DB01026,10016173,36,1074,26,1042,0.302701139,1.343175524,0.782537815,2.334542536,0.469050253,DB0102610016173_,0.757045368,0.295036604,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ketoconazole,DB01026
,142000,DB00635,10016454,77,32976,31,23763,0.006027879,1.789890205,1.165133703,2.811516751,0.023750984,DB0063510016454_,3.740131332,0.58215428,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,142013,DB01026,10033371,40,1070,26,1042,0.133201762,1.497920839,0.884619116,2.576555892,0.260196813,DB0102610033371_,1.346316963,0.404078039,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ketoconazole,DB01026
,142056,DB00989,10003549,20,814,37,841,0.042746158,0.558658061,0.304473019,0.997385458,0.111218288,DB0098910003549_,2.196260447,-0.582217691,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,rivastigmine,DB00989
,142057,DB01593,10003549,53,1080,30,668,0.730271777,1.092680106,0.67767606,1.790677531,0.843096241,DB0159310003549_,0.170674163,0.088633491,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,zinc,DB01593
,142077,DB01593,10013573,50,1083,30,668,1,1.027994913,0.633800031,1.692658617,1,DB0159310013573_,0,0.027610219,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,zinc,DB01593
,142097,DB00451,10048439,146,47125,10,15409,3.59637959666052e-09,4.773930687,2.522339641,10.16848515,8.91088126165405e-08,DB0045110048439_,16.2334076,1.563170009,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,142103,DB00641,10061422,20,14104,44,12431,0.000595682,0.400639741,0.223571663,0.694650643,0.003575181,DB0064110061422_,5.63373957,-0.914692658,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,142114,DB00451,10040872,40,47231,18,15401,0.284688469,0.724622479,0.405821521,1.343242701,0.4492193,DB0045110040872_,0.800244092,-0.322104478,NA,10040872,Skin infection,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,142134,DB00544,10015150,33,2402,31,2622,0.614992481,1.16197967,0.687528295,1.968383972,0.756473273,DB0054410015150_,0.279088077,0.150125162,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,fluorouracil,DB00544
,142167,DB06403,10005191,48,21423,7,6654,0.057096222,2.129682457,0.957527677,5.581829552,0.137976849,DB0640310005191_,1.980669372,0.755972888,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,ambrisentan,DB06403
,142170,DB00820,10053505,86,11829,13,5803,1.2463502404191e-05,3.245167744,1.798922225,6.345994751,0.000131594,DB0082010053505_,8.935789445,1.177167042,female,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,142172,DB06403,10053505,84,21387,13,6648,0.016258732,2.00839017,1.112360007,3.930801584,0.052501322,DB0640310053505_,2.946916923,0.697333491,NA,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,142182,DB00741,10001760,42,4052,12,3162,0.001347772,2.730852779,1.408588306,5.707615514,0.007040182,DB0074110001760_,4.956121311,1.004613934,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocortisone,DB00741
,142189,DB00433,10023232,47,7609,28,5992,0.293814758,1.321827866,0.809681001,2.194809698,0.459547227,DB0043310023232_,0.777513564,0.279015525,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,prochlorperazine,DB00433
,142190,DB00741,10023232,44,4050,19,3155,0.030392651,1.803877576,1.029119583,3.278514705,0.08553221,DB0074110023232_,2.458862249,0.589938557,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocortisone,DB00741
,142198,DB00433,10044565,66,7590,48,5972,0.70561154,1.081900782,0.733483693,1.606000487,0.823597413,DB0043310044565_,0.194073445,0.078719478,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,142205,DB00316,10042945,89,65385,9,36944,1.29800955700747e-09,5.58815826,2.814082452,12.61947095,3.52825038324109e-08,DB0031610042945_,17.15987864,1.720649762,female,10042945,Systemic lupus erythematosus,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,142230,DB01234,10021688,46,31579,43,32845,0.671633655,1.112652005,0.717836804,1.72764611,0.800757065,DB0123410021688_,0.222197668,0.106746359,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,dexamethasone,DB01234
,142232,DB01075,10022004,169,19779,46,11051,5.88139601585447e-06,2.05265867,1.472485569,2.911763013,6.80874231564566e-05,DB0107510022004_,9.594718044,0.719135865,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,142236,DB00889,10025482,44,736,21,496,0.242142959,1.411645352,0.810077359,2.532142331,0.400366996,DB0088910025482_,0.915373663,0.34475594,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,granisetron,DB00889
,142241,DB01234,10049848,211,31414,206,32682,0.52333646,1.06564659,0.874719413,1.298310466,0.681643113,DB0123410049848_,0.383249052,0.063581742,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,142243,DB00787,10002855,162,16838,90,17158,3.37219560026845e-06,1.834164117,1.407606655,2.402705084,4.18618706189331e-05,DB0078710002855_,10.08113515,0.606588855,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,acyclovir,DB00787
,142260,DB00153,10020583,38,7385,14,3425,0.550761421,1.258768338,0.66564673,2.518513238,0.704818102,DB0015310020583_,0.349815521,0.230133734,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,ergocalciferol,DB00153
,142262,DB00787,10020583,36,16964,25,17223,0.159134323,1.461961644,0.853268239,2.541994025,0.296319473,DB0078710020583_,1.216317104,0.379779126,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,acyclovir,DB00787
,142264,DB00335,10022004,51,8415,14,5451,0.00316721,2.359602354,1.284928282,4.620522444,0.01414255,DB0033510022004_,4.25856726,0.858493111,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,atenolol,DB00335
,142269,DB01234,10022061,38,31587,18,32870,0.004874953,2.196844495,1.223072094,4.09022937,0.020050731,DB0123410022061_,3.909489681,0.78702201,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,142272,DB00335,10027599,58,8408,11,5454,3.42501165243296e-05,3.41998592,1.775372784,7.233248787,0.000318621,DB0033510027599_,8.051507497,1.229636434,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,142273,DB00787,10027599,49,16951,14,17234,6.14916610216011e-06,3.557953837,1.932338406,6.980790387,7.0859636560841e-05,DB0078710027599_,9.554809588,1.269185615,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,142274,DB01234,10027599,72,31553,20,32868,1.23994290817976e-08,3.749569507,2.25849591,6.500183297,2.73536712895552e-07,DB0123410027599_,15.11182999,1.321641035,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,142291,DB01076,10031282,56,25691,12,25571,6.15444032511296e-08,4.644537082,2.460208309,9.52052024,1.16632634423644e-06,DB0107610031282_,13.66165163,1.535691708,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,142292,DB01234,10031282,45,31580,18,32870,0.000361637,2.60214779,1.476223054,4.777361547,0.002357256,DB0123410031282_,6.050256912,0.956337177,NA,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,142321,DB00710,10028813,142,2264,9,192,0.528498492,1.337910362,0.670674667,3.034038744,0.685868611,DB0071010028813_,0.377069198,0.291108965,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ibandronate,DB00710
,142331,DB00710,10011906,41,2365,12,189,0.000502031,0.273278858,0.138016222,0.581178118,0.003101267,DB0071010011906_,5.775944409,-1.297262549,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ibandronate,DB00710
,142335,DB09029,10013968,169,11175,88,7182,0.122220695,1.23421155,0.946624432,1.618585627,0.244627524,DB0902910013968_,1.408018537,0.210432345,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,secukinumab,DB09029
,142343,DB14500,10020937,96,7713,27,4046,0.003972205,1.865045823,1.203841096,2.979353188,0.016982664,DB1450010020937_,4.075562206,0.623285623,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,potassium,DB14500
,142346,DB00471,10033775,132,14057,40,5425,0.199931141,1.273530723,0.886666315,1.865179247,0.348892285,DB0047110033775_,1.052992043,0.24179314,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,142347,DB14500,10033775,82,7727,35,4038,0.329871285,1.224282283,0.813152533,1.878157115,0.498543395,DB1450010033775_,0.696064642,0.20235478,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,potassium,DB14500
,142348,DB00203,10007815,100,13778,49,8889,0.129470523,1.316634695,0.925393975,1.895095723,0.254887669,DB0020310007815_,1.366932346,0.275079008,NA,10007815,Catheterisation cardiac,10022891,Investigations,Inv,sildenafil,DB00203
,142349,DB08932,10007815,135,19308,41,6556,0.601875807,1.118019124,0.782029607,1.628933646,0.746048066,DB0893210007815_,0.292965249,0.11155848,NA,10007815,Catheterisation cardiac,10022891,Investigations,Inv,macitentan,DB08932
,142350,DB00203,10037324,100,13778,22,8916,5.7035732126293e-07,2.941306897,1.838241021,4.90617491,8.71365428038135e-06,DB0020310037324_,11.65061931,1.078854005,female,10037324,Pulmonary arterial pressure increased,10022891,Investigations,Inv,sildenafil,DB00203
,142351,DB08932,10037324,125,19318,29,6568,0.06341362,1.465433596,0.971025702,2.279810021,0.149652271,DB0893210037324_,1.899440871,0.382151169,NA,10037324,Pulmonary arterial pressure increased,10022891,Investigations,Inv,macitentan,DB08932
,142352,DB00203,10043554,48,13830,27,8911,0.636259757,1.145491418,0.699937507,1.910846884,0.773906548,DB0020310043554_,0.256304152,0.135833731,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,sildenafil,DB00203
,142353,DB05259,10000059,49,11221,8,2720,0.401070133,1.484669315,0.696254684,3.634369216,0.570893991,DB0525910000059_,0.560551741,0.395192064,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,glatiramer,DB05259
,142371,DB09027,10019744,71,5108,329,6823,1.07089569462005e-25,0.288292829,0.219265183,0.374668735,1.7269014314778e-23,DB0902710019744_,52.41312842,-1.243778548,male,10019744,Hepatitis C,10021881,Infections and infestations,Infec,ledipasvir,DB09027
,142440,DB00215,10029331,67,11036,38,5238,0.402233218,0.836868547,0.553094565,1.282744618,0.572022947,DB0021510029331_,0.558576171,-0.178088273,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,142441,DB00650,10029331,82,2049,86,1928,0.52864033,0.897205847,0.650407365,1.236884636,0.686018813,DB0065010029331_,0.376850227,-0.10846996,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,leucovorin,DB00650
,142450,DB00404,10000381,45,19847,48,9814,0.000241103,0.463581701,0.30145494,0.711750458,0.00168324,DB0040410000381_,6.387034603,-0.768772639,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,142475,DB00264,10003983,36,29571,28,24864,0.802565017,1.081084165,0.641299984,1.839699718,0.893211452,DB0026410003983_,0.112931938,0.077964394,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,142476,DB00381,10003983,44,29316,39,22848,0.580994871,0.879292407,0.558100144,1.390030069,0.72942347,DB0038110003983_,0.315500824,-0.128637778,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,142488,DB00381,10052428,34,29326,19,22868,0.269541319,1.395395755,0.773448637,2.590353518,0.432097922,DB0038110052428_,0.839103045,0.333178071,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,142489,DB00451,10052428,78,47193,31,15388,0.372917263,0.820408239,0.534522743,1.287807736,0.542627581,DB0045110052428_,0.611332049,-0.19795321,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,142506,DB00451,10022687,92,47179,34,15385,0.534856119,0.882370484,0.589218458,1.349662247,0.691405468,DB0045110022687_,0.369028843,-0.125143261,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,142509,DB14500,10010774,156,7653,60,4013,0.042876075,1.363326934,1.003425916,1.872918996,0.11146253,DB1450010010774_,2.194066796,0.309927988,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,142525,DB00818,10011906,31,1389,42,1635,0.63481069,0.868855747,0.524982827,1.424004778,0.772965164,DB0081810011906_,0.257521298,-0.140578166,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,propofol,DB00818
,142535,DB00331,10073317,64,24882,66,20686,0.251426007,0.806178345,0.562250975,1.155280571,0.411412992,DB0033110073317_,0.888157723,-0.215450289,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,142548,DB06605,10051398,29,14044,46,12987,0.027258084,0.583002629,0.352951962,0.948618297,0.078574187,DB0660510051398_,2.543712038,-0.539563583,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,apixaban,DB06605
,142555,DB00005,10027145,42,128040,10,42409,0.423351813,1.39108616,0.686767026,3.109447991,0.59219248,DB0000510027145_,0.523923561,0.330084852,NA,10027145,Melanocytic naevus,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,etanercept,DB00005
,142558,DB00996,10022094,53,38900,17,22408,0.034624519,1.795875753,1.023256843,3.309412264,0.094679375,DB0099610022094_,2.3572591,0.585492788,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,142568,DB00338,10051608,40,33634,21,22251,0.433909294,1.260103283,0.725285578,2.250201425,0.602451247,DB0033810051608_,0.506748535,0.231193688,NA,10051608,Platelet count increased,10022891,Investigations,Inv,omeprazole,DB00338
,142569,DB00480,10051608,42,67386,22,67640,0.012339675,1.916266408,1.118114928,3.370951833,0.042087634,DB0048010051608_,3.1680013,0.650378714,NA,10051608,Platelet count increased,10022891,Investigations,Inv,lenalidomide,DB00480
,142610,DB00996,10002948,78,38875,45,22380,1,0.99786487,0.682479579,1.474575596,1,DB0099610002948_,0,-0.002137413,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,142615,DB00996,10013395,106,38847,59,22366,0.871638344,1.034392093,0.745094422,1.448002262,0.943480712,DB0099610013395_,0.058179357,0.033813905,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,142618,DB00514,10022437,35,2131,17,1519,0.205479652,1.467404393,0.7968897,2.804127866,0.355787534,DB0051410022437_,1.033421542,0.383495121,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,dextromethorphan,DB00514
,142623,DB00996,10054196,37,38916,22,22403,0.893206235,0.968158247,0.556140725,1.723389227,0.955474763,DB0099610054196_,0.045546928,-0.032359727,NA,10054196,Affect lability,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,142648,DB00186,10018100,50,16851,24,9984,0.47014111,1.234373886,0.743919074,2.101447298,0.636385872,DB0018610018100_,0.451950182,0.210563867,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,142654,DB00186,10020100,47,16854,24,9984,0.623565228,1.16010414,0.694727619,1.98479823,0.763571804,DB0018610020100_,0.269748113,0.148509777,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,142655,DB00264,10020100,126,29481,64,24828,0.000978448,1.6580018,1.217139716,2.277668961,0.005409865,DB0026410020100_,5.219531073,0.505613142,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,142665,DB01592,10047571,46,6230,18,3049,0.504567077,1.250639398,0.709824664,2.295791536,0.665548334,DB0159210047571_,0.407144016,0.223654939,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,iron,DB01592
,142683,DB00381,10005191,118,29242,77,22810,0.247319453,1.195385102,0.889008448,1.615250123,0.406540872,DB0038110005191_,0.900070809,0.178468394,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,142684,DB00215,10029354,61,11042,42,5234,0.07169819,0.688443248,0.456521272,1.047032482,0.164244156,DB0021510029354_,1.806401199,-0.373322393,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,citalopram,DB00215
,142713,DB00338,10000381,45,33629,21,22251,0.209009723,1.41783607,0.826963091,2.506308063,0.36006284,DB0033810000381_,1.021476706,0.349131815,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,142717,DB06285,10022086,174,8676,14,1092,0.126558123,1.564254794,0.903411233,2.931687876,0.250882783,DB0628510022086_,1.382769451,0.447409541,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,142731,DB00586,10012378,151,6958,34,2771,0.002206024,1.76859445,1.208890693,2.654290807,0.01053417,DB0058610012378_,4.553131014,0.570185135,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,diclofenac,DB00586
,142735,DB00169,10037162,157,38534,42,18133,0.000776739,1.759024985,1.243758691,2.536549878,0.00446313,DB0016910037162_,5.411904961,0.56475967,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,142737,DB00341,10037162,55,11350,16,5052,0.15611874,1.530035596,0.863000392,2.863674251,0.292288264,DB0034110037162_,1.230014757,0.425291,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,142738,DB00476,10037162,136,17121,27,6150,0.004126362,1.809375059,1.189163517,2.848379077,0.017522038,DB0047610037162_,4.044295855,0.592981514,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,142739,DB00586,10037162,73,7036,23,2782,0.365082708,1.254904498,0.774288189,2.106176185,0.534696549,DB0058610037162_,0.62605589,0.227059472,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,142740,DB00722,10037162,104,25299,56,25976,9.25859709961041e-05,1.906803771,1.364335771,2.689520519,0.000747083,DB0072210037162_,7.199334525,0.645428422,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,142741,DB00736,10037162,47,10544,7,5546,0.000493276,3.531409103,1.584802726,9.265846818,0.003058684,DB0073610037162_,5.789770572,1.261696971,female,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,142744,DB01156,10037162,84,13538,17,6311,0.000840662,2.303343953,1.355085613,4.143013543,0.004769435,DB0115610037162_,5.345527328,0.83436196,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,142746,DB13961,10037162,62,9395,18,6396,0.000855251,2.344808596,1.367620982,4.216811544,0.004839671,DB1396110037162_,5.330908523,0.852203776,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,142758,DB08893,10046571,102,1983,32,1026,0.014909721,1.648964412,1.090045674,2.554521431,0.049079778,DB0889310046571_,3.014308189,0.500147462,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,mirabegron,DB08893
,142764,DB00987,10020772,38,2066,61,2867,0.537419972,0.864516273,0.558555844,1.323079877,0.693587525,DB0098710020772_,0.36587784,-0.14558515,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,cytarabine,DB00987
,142773,DB00480,10009245,20,67408,32,67630,0.126303725,0.627064117,0.339846015,1.130668123,0.250513908,DB0048010009245_,1.38424084,-0.466706484,NA,10009245,Clavicle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,142775,DB00741,10020751,46,4048,25,3149,0.185583195,1.431293023,0.859046969,2.436760511,0.330910323,DB0074110020751_,1.105907867,0.358578247,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,hydrocortisone,DB00741
,142781,DB00687,10047700,40,946,20,1065,0.003573989,2.250738892,1.274640278,4.094665743,0.015583031,DB0068710047700_,4.161572729,0.811258559,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,fludrocortisone,DB00687
,142782,DB00404,10001551,51,19841,20,9842,0.44900285,1.264859089,0.740474062,2.241310386,0.616664834,DB0040410001551_,0.483429622,0.234960723,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,alprazolam,DB00404
,142783,DB00404,10003481,48,19844,23,9839,1,1.034725556,0.616792448,1.783585146,1,DB0040410003481_,0,0.034136228,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,alprazolam,DB00404
,142784,DB00736,10008469,71,10520,31,5522,0.464282166,1.20216155,0.77690522,1.899742974,0.631446807,DB0073610008469_,0.459741573,0.184121228,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,142802,DB01296,10028334,31,1418,19,964,0.77253421,1.109176727,0.60308197,2.090956575,0.875506573,DB0129610028334_,0.132952619,0.103618053,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,glucosamine,DB01296
,142821,DB01327,10013709,25,638,51,706,0.013213599,0.542670181,0.318230933,0.904242799,0.044456891,DB0132710013709_,3.113235297,-0.611253545,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cefazolin,DB01327
,142822,DB09140,10013709,70,3671,52,1746,0.018656061,0.640301688,0.438744823,0.939582452,0.058492819,DB0914010013709_,2.838851276,-0.445815826,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,142828,DB00927,10000060,77,7420,49,4967,0.855123557,1.051927354,0.724422052,1.540160509,0.929797415,DB0092710000060_,0.07278855,0.050624056,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,142858,DB00338,10003119,50,33624,41,22231,0.335030666,0.806309106,0.52266118,1.250245701,0.50419564,DB0033810003119_,0.684790912,-0.215288103,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,omeprazole,DB00338
,142859,DB01118,10003119,21,3042,36,4673,0.785958592,0.896086776,0.496032528,1.580450409,0.883823038,DB0111810003119_,0.12349842,-0.109718022,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,amiodarone,DB01118
,142864,DB11097,10016173,33,821,25,658,0.89328605,1.057904607,0.603432947,1.875699598,0.955501814,DB1109710016173_,0.045518617,0.056290166,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,plantago seed,DB11097
,142865,DB00761,10019196,61,15246,35,8590,0.915632941,0.981964236,0.637144502,1.534753724,0.962215366,DB0076110019196_,0.03851698,-0.018200391,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,142872,DB01118,10038695,55,3008,104,4605,0.219519746,0.809651325,0.57108074,1.13711601,0.372883499,DB0111810038695_,0.986489243,-0.211151587,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,142897,DB00043,10016322,49,6364,22,2278,0.416918309,0.797261648,0.471812993,1.387995034,0.586073629,DB0004310016322_,0.534309851,-0.226572363,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,142903,DB00230,10005169,65,19609,29,8622,1,0.985525919,0.626531782,1.585045551,1,DB0023010005169_,0,-0.014579852,NA,10005169,Blindness,10015919,Eye disorders,Eye,pregabalin,DB00230
,142913,DB00196,10047895,91,4992,76,3209,0.10913627,0.769739068,0.559465692,1.061535259,0.224735979,DB0019610047895_,1.492828992,-0.261703694,NA,10047895,Weight decreased,10022891,Investigations,Inv,fluconazole,DB00196
,142914,DB00264,10023469,42,29565,19,24873,0.028033857,1.859668911,1.057750022,3.386533316,0.08029967,DB0026410023469_,2.521989767,0.620398467,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,metoprolol,DB00264
,142915,DB00316,10023469,93,65381,39,36914,0.123764201,1.346345895,0.916806914,2.01081312,0.246749244,DB0031610023469_,1.399382666,0.297394178,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,142918,DB01076,10023469,41,25706,21,25562,0.015105239,1.941408756,1.120653678,3.459034761,0.049596292,DB0107610023469_,3.003839201,0.663413872,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,atorvastatin,DB01076
,142919,DB00175,10005425,34,8097,16,6090,0.151681479,1.598224505,0.857493803,3.103887718,0.286284973,DB0017510005425_,1.250767556,0.468893329,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,pravastatin,DB00175
,142920,DB00588,10005425,38,16486,23,8445,0.588167194,0.846346542,0.491056795,1.489059241,0.735121594,DB0058810005425_,0.307719359,-0.16682638,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,142924,DB01590,10005557,72,4666,41,2826,0.845028228,1.063592787,0.712794774,1.605850266,0.921765987,DB0159010005557_,0.081463898,0.061652599,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,everolimus,DB01590
,142930,DB01241,10025482,35,908,21,1050,0.020450317,1.926668658,1.081876348,3.509927481,0.062891842,DB0124110025482_,2.766338815,0.655792428,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,gemfibrozil,DB01241
,142932,DB01065,10003658,41,4290,46,3005,0.036829062,0.624384782,0.39855323,0.975179865,0.099231787,DB0106510003658_,2.310296885,-0.470988463,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,melatonin,DB01065
,142933,DB00836,10006093,44,5491,56,4019,0.007859193,0.575130338,0.377635809,0.871044689,0.029358186,DB0083610006093_,3.528183849,-0.553158589,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,loperamide,DB00836
,142937,DB01065,10013968,199,4132,121,2930,0.201850258,1.166162288,0.920861794,1.481694983,0.351238558,DB0106510013968_,1.046289635,0.153718262,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,melatonin,DB01065
,142944,DB00215,10037423,53,11050,25,5251,1,1.007433079,0.614317906,1.693916699,1,DB0021510037423_,0,0.00740559,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,142947,DB00836,10037423,45,5490,22,4053,0.136132841,1.509995556,0.886357239,2.645035407,0.264301933,DB0083610037423_,1.330663143,0.412106707,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loperamide,DB00836
,142949,DB00215,10038695,123,10980,35,5241,0.006073099,1.677399291,1.142241022,2.520657056,0.023893339,DB0021510038695_,3.734155545,0.517244553,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,142954,DB00836,10043071,79,5456,92,3983,0.002909665,0.626911178,0.456824016,0.858644361,0.013177212,DB0083610043071_,4.32926633,-0.46695041,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,loperamide,DB00836
,142955,DB01065,10043071,38,4293,31,3020,0.541799064,0.862339339,0.521199953,1.436771516,0.697150876,DB0106510043071_,0.360753427,-0.14810642,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,melatonin,DB01065
,142960,DB00688,10008531,44,6446,33,5345,0.730857491,1.105552613,0.687029364,1.795000123,0.843454003,DB0068810008531_,0.170249909,0.100345312,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,142968,DB14513,10022061,58,7119,8,3556,0.000114994,3.621010363,1.718482161,8.792078985,0.000898519,DB1451310022061_,7.01476276,1.286753093,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,142972,DB01175,10022095,109,10615,28,4864,0.00535147,1.783724326,1.166726462,2.811383341,0.021596543,DB0117510022095_,3.835222018,0.578703497,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,142974,DB01175,10053425,51,10673,12,4880,0.040334525,1.943149371,1.020866799,4.007882081,0.106300997,DB0117510053425_,2.241480618,0.664310044,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,142981,DB00005,10061590,51,128031,21,42398,0.413541119,0.804223643,0.475162329,1.407779274,0.582916818,DB0000510061590_,0.539710782,-0.217877886,NA,10061590,Blood disorder,10005329,Blood and lymphatic system disorders,Blood,etanercept,DB00005
,143002,DB00758,10037087,158,8142,115,9959,2.83029046720262e-05,1.680448349,1.310796332,2.159895606,0.000269642,DB0075810037087_,8.218415981,0.519060632,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,clopidogrel,DB00758
,143016,DB00678,10005555,51,15548,32,10692,0.737825578,1.096001407,0.690422418,1.763539059,0.848953281,DB0067810005555_,0.163751123,0.091668472,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,losartan,DB00678
,143018,DB01307,10005555,54,2470,34,2035,0.235526915,1.308448793,0.832820439,2.081445164,0.392656896,DB0130710005555_,0.934819086,0.268842308,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,insulin detemir,DB01307
,143020,DB00727,10020751,53,3790,28,4145,0.001650564,2.069956576,1.282860072,3.406248148,0.00830734,DB0072710020751_,4.790615812,0.727527629,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,nitroglycerin,DB00727
,143022,DB01005,10053762,44,1051,39,828,0.651840621,0.888878691,0.558562939,1.41914232,0.78617341,DB0100510053762_,0.240577888,-0.117794509,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxyurea,DB01005
,143028,DB00588,10013990,48,16476,24,8444,1,1.025005719,0.615127565,1.750935732,1,DB0058810013990_,0,0.024698193,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,fluticasone propionate,DB00588
,143038,DB00169,10034829,40,38651,13,18162,0.30244234,1.445842121,0.757318056,2.947017457,0.468827608,DB0016910034829_,0.757520151,0.368691934,NA,10034829,Pharyngeal oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,143051,DB11097,10046571,43,811,11,672,0.000233994,3.23678278,1.625612979,7.017929001,0.001641678,DB1109710046571_,6.412036601,1.174579867,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,plantago seed,DB11097
,143065,DB00331,10003553,157,24789,34,20718,1.11699354588213e-15,3.859117925,2.64843367,5.771235419,7.43295578569921e-14,DB0033110003553_,30.2302677,1.350438641,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,143068,DB01104,10003553,79,15384,13,7273,0.00011653,2.872842364,1.585757561,5.635552037,0.000909762,DB0110410003553_,7.002327396,1.055301911,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,143069,DB08910,10003553,51,16693,21,17467,0.000209925,2.541162848,1.500791047,4.449630476,0.001500446,DB0891010003553_,6.501993175,0.932621791,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,143070,DB00186,10036018,45,16856,27,9981,1,0.986885344,0.598792177,1.655237374,1,DB0018610036018_,0,-0.013201413,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,lorazepam,DB00186
,143074,DB00904,10036018,47,23022,36,14420,0.368251678,0.817756841,0.518278536,1.300038208,0.537988848,DB0090410036018_,0.619917448,-0.201190248,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,ondansetron,DB00904
,143075,DB00996,10036018,99,38854,44,22381,0.16449984,1.296066721,0.89956514,1.894069178,0.30342354,DB0099610036018_,1.192625628,0.259334079,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,143076,DB08910,10036018,28,16716,40,17448,0.22523892,0.730662215,0.433907807,1.214831553,0.380133266,DB0891010036018_,0.967233388,-0.313804012,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,pomalidomide,DB08910
,143095,DB13867,10008469,58,4492,17,2537,0.015421041,1.926742079,1.103592149,3.537433422,0.050381216,DB1386710008469_,2.988136875,0.655830535,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,143128,DB06285,10006002,245,8605,21,1085,0.093112205,1.470993482,0.936011326,2.430211114,0.200274482,DB0628510006002_,1.608066443,0.38593801,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,teriparatide,DB06285
,143142,DB00381,10052251,35,29325,20,22867,0.280077615,1.364602541,0.766003195,2.495300391,0.443926261,DB0038110052251_,0.81209681,0.310863207,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,143168,DB00153,10062355,53,7370,22,3417,0.710305206,1.116926942,0.66650654,1.9318171,0.827202425,DB0015310062355_,0.189705844,0.110581112,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,143170,DB01076,10062355,159,25588,125,25458,0.049714915,1.265528885,0.99420916,1.613814258,0.124488572,DB0107610062355_,2.083541362,0.235490126,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,143183,DB00230,10005425,65,19609,24,8627,0.491810517,1.191514734,0.735258391,1.99165589,0.654875352,DB0023010005425_,0.423310364,0.175225383,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,pregabalin,DB00230
,143190,DB05259,10022107,274,10996,41,2687,0.003078684,1.632979023,1.169327808,2.33280384,0.013824755,DB0525910022107_,4.281294482,0.490405969,NA,10022107,Injection site urticaria,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,143192,DB05259,10047895,59,11211,16,2712,0.66199001,0.892011771,0.505625559,1.66362423,0.793904753,DB0525910047895_,0.230791783,-0.11427595,NA,10047895,Weight decreased,10022891,Investigations,Inv,glatiramer,DB05259
,143203,DB00213,10021143,129,18766,106,13315,0.287790964,0.863488692,0.661946528,1.128368028,0.452806506,DB0021310021143_,0.792290383,-0.146774477,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,143210,DB00853,10035664,18,1803,32,2234,0.253113414,0.697024514,0.367080426,1.284670513,0.413504838,DB0085310035664_,0.883086065,-0.360934698,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,temozolomide,DB00853
,143213,DB00213,10035742,34,18861,50,13371,0.001170158,0.482072531,0.302190207,0.760753639,0.006272579,DB0021310035742_,5.071567653,-0.729660698,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,143228,DB00695,10018836,119,27930,68,20460,0.103386167,1.281947672,0.943213861,1.754249536,0.216095216,DB0069510018836_,1.532036154,0.24838054,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,143233,DB00264,10064366,34,29573,17,24875,0.091074984,1.682257665,0.913847052,3.211760999,0.196988764,DB0026410064366_,1.624608587,0.52013674,NA,10064366,Extra dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,143238,DB00530,10016173,40,1768,21,1247,0.295916982,1.343334378,0.769060038,2.410627684,0.461765581,DB0053010016173_,0.772697916,0.295154865,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,erlotinib,DB00530
,143241,DB00927,10016322,111,7386,41,4975,0.000821485,1.823485459,1.261314236,2.681819972,0.004681353,DB0092710016322_,5.364168148,0.600749757,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,143242,DB01234,10016322,388,31237,294,32594,3.6892515276589e-05,1.377046102,1.179382639,1.609243264,0.000340193,DB0123410016322_,7.985997849,0.319940699,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,143251,DB00404,10009033,127,19765,48,9814,0.125639702,1.313775202,0.934656086,1.873244611,0.249560913,DB0040410009033_,1.388052254,0.272904826,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,143252,DB00476,10009033,86,17171,32,6145,0.834551739,0.961777283,0.633393888,1.493599993,0.91418995,DB0047610009033_,0.089716907,-0.038972369,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,143253,DB00678,10009033,92,15507,47,10677,0.100473528,1.347740834,0.937560374,1.960142226,0.211529571,DB0067810009033_,1.553390475,0.298429734,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,143268,DB00215,10046735,78,11025,19,5257,0.006398496,1.957423468,1.172373667,3.42741451,0.02492296,DB0021510046735_,3.691965802,0.671629051,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,citalopram,DB00215
,143270,DB00761,10046735,88,15219,26,8599,0.003174569,1.912318379,1.221579717,3.08945225,0.014170595,DB0076110046735_,4.256586265,0.648316317,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,potassium chloride,DB00761
,143272,DB00678,10051055,66,15533,76,10648,0.002597537,0.595338258,0.421106572,0.83979098,0.01202044,DB0067810051055_,4.421146784,-0.518625534,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,losartan,DB00678
,143280,DB01174,10053762,48,891,48,744,0.400858432,0.835106822,0.541049991,1.288921609,0.570716275,DB0117410053762_,0.560863084,-0.180195631,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,phenobarbital,DB01174
,143330,DB00182,10013968,123,5071,38,2814,0.001483365,1.796069136,1.23520391,2.664978389,0.007621468,DB0018210013968_,4.876786237,0.585600464,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amphetamine,DB00182
,143337,DB00695,10019660,60,27989,55,20473,0.256679836,0.797972423,0.543893978,1.172716847,0.417531889,DB0069510019660_,0.873394356,-0.22568124,NA,10019660,Hepatic encephalopathy,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,143355,DB00715,10013654,37,4806,68,2219,5.07020267494412e-12,0.251293482,0.163113697,0.381744101,2.05031195862933e-10,DB0071510013654_,22.30785897,-1.38113377,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,paroxetine,DB00715
,143367,DB00327,10028372,56,6082,38,4224,1,1.023485305,0.664619913,1.59145593,1,DB0032710028372_,0,0.023213768,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydromorphone,DB00327
,143377,DB00373,10011906,42,1790,40,1247,0.173194352,0.731566997,0.460018333,1.164903788,0.315100436,DB0037310011906_,1.154863845,-0.312566474,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,timolol,DB00373
,143381,DB00196,10054112,61,5022,32,3253,0.393101226,1.234722589,0.790332501,1.962324519,0.563057366,DB0019610054112_,0.574373762,0.210846321,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,fluconazole,DB00196
,143384,DB00635,10054112,335,32718,244,23550,0.898969537,0.988230482,0.834680854,1.171329573,0.956490275,DB0063510054112_,0.044484657,-0.011839327,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,prednisone,DB00635
,143387,DB01015,10054112,119,9768,108,9273,0.739042851,1.046025534,0.798007225,1.372327077,0.849862904,DB0101510054112_,0.162680232,0.044997776,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,sulfamethoxazole,DB01015
,143388,DB01039,10054112,21,2952,33,3018,0.133693328,0.650640308,0.356842801,1.161654341,0.260904975,DB0103910054112_,1.343599017,-0.429798312,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,fenofibrate,DB01039
,143389,DB00697,10007882,46,6050,23,1783,0.043509265,0.589467039,0.348923794,1.021864272,0.112651796,DB0069710007882_,2.183453667,-0.528536474,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,tizanidine,DB00697
,143390,DB01069,10007882,48,6652,22,2373,0.340951647,0.778348414,0.459703918,1.357130306,0.510170725,DB0106910007882_,0.673009854,-0.250581022,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,promethazine,DB01069
,143391,DB01175,10007882,46,10678,27,4865,0.312177044,0.776207469,0.471869363,1.300195542,0.479675772,DB0117510007882_,0.734644879,-0.253335438,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,escitalopram,DB01175
,143402,DB11133,10010774,65,2366,28,1546,0.068467933,1.516725033,0.954940135,2.465940992,0.158534146,DB1113310010774_,1.841785279,0.416553427,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,omega-3 fatty acids,DB11133
,143404,DB00399,10013946,68,6924,24,4974,0.002020335,2.03525974,1.259277033,3.39510219,0.009806926,DB0039910013946_,4.624666435,0.710623447,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,143406,DB01060,10013946,51,8536,19,5062,0.083907234,1.591733375,0.922464718,2.858243244,0.184916714,DB0106010013946_,1.68784975,0.464823595,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,143414,DB00804,10022437,62,2938,23,876,0.364140463,0.803788717,0.487597673,1.367833619,0.533707986,DB0080410022437_,0.627906433,-0.218418834,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,dicyclomine,DB00804
,143415,DB11133,10022437,46,2385,35,1539,0.491358982,0.848126497,0.531892037,1.363010952,0.654512919,DB1113310022437_,0.423863955,-0.164725484,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,omega-3 fatty acids,DB11133
,143417,DB00804,10028334,63,2937,14,885,0.341269877,1.355862474,0.747004442,2.633624564,0.510428969,DB0080410028334_,0.67250379,0.304437764,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,dicyclomine,DB00804
,143443,DB06186,10019211,69,2140,55,3591,4.84881901514119e-05,2.104928703,1.449203478,3.069458407,0.000430578,DB0618610019211_,7.750381126,0.744281596,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ipilimumab,DB06186
,143444,DB09035,10019211,95,4631,64,6626,3.0874442502567e-06,2.12371534,1.527025615,2.969797191,3.88573005113705e-05,DB0903510019211_,10.15561458,0.753167074,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,nivolumab,DB09035
,143467,DB00321,10042458,47,7400,20,2830,0.682319067,0.898733032,0.521192015,1.604173318,0.807853728,DB0032110042458_,0.213374267,-0.10676925,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,amitriptyline,DB00321
,143468,DB00656,10042458,147,11866,99,6520,0.123221512,0.815899749,0.626905151,1.065602726,0.245975125,DB0065610042458_,1.402524867,-0.203463788,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,143480,DB01029,10016173,47,1293,18,883,0.039863234,1.782714699,1.00810604,3.284389545,0.105418292,DB0102910016173_,2.249819107,0.578137314,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,irbesartan,DB01029
,143481,DB01029,10019211,55,1285,25,876,0.10456813,1.499506032,0.910728643,2.531853353,0.217881355,DB0102910019211_,1.523804607,0.405135742,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,irbesartan,DB01029
,143482,DB01203,10019211,42,657,24,481,0.371388183,1.280943181,0.746409609,2.243470924,0.541008758,DB0120310019211_,0.614319811,0.247596666,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,nadolol,DB01203
,143483,DB01029,10025482,47,1293,19,882,0.056712189,1.687011929,0.963587682,3.065797222,0.137313916,DB0102910025482_,1.985485614,0.522958875,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,irbesartan,DB01029
,143487,DB00341,10040979,55,11350,25,5043,0.903889391,0.977498619,0.598140196,1.639041149,0.95743432,DB0034110040979_,0.043498156,-0.0227584,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,143489,DB00736,10040979,37,10554,13,5540,0.235349997,1.493966753,0.775383414,3.065637041,0.392461517,DB0073610040979_,0.935316792,0.401434833,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,143502,DB00177,10042772,30,4770,29,2821,0.077854276,0.611866074,0.354019059,1.058875912,0.174734206,DB0017710042772_,1.744489283,-0.491241854,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,valsartan,DB00177
,143503,DB00697,10042772,60,6036,19,1787,0.788196672,0.934917482,0.5484806,1.663558081,0.885260416,DB0069710042772_,0.121873422,-0.067297008,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,143517,DB00341,10062355,75,11330,35,5033,0.835904372,0.951901132,0.628289778,1.467527611,0.915146254,DB0034110062355_,0.088671386,-0.049294102,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,143540,DB00734,10020751,37,4013,13,4889,4.52064051649277e-05,3.466987128,1.798196282,7.118259324,0.000405615,DB0073410020751_,7.8101051,1.243285954,female,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,risperidone,DB00734
,143541,DB01190,10020751,68,4866,23,2262,0.212628736,1.374339908,0.842971294,2.317491348,0.364575754,DB0119010020751_,1.009020918,0.317973549,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,clindamycin,DB01190
,143553,DB00455,10003553,109,9292,31,5087,0.000944675,1.924861816,1.279253205,2.973298751,0.00525519,DB0045510003553_,5.248539085,0.654854181,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,143554,DB01156,10003553,65,13557,8,6320,4.36475940170243e-05,3.787138965,1.811162087,9.147324902,0.000394007,DB0115610003553_,7.839141159,1.331610844,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,143555,DB00471,10013971,79,14110,23,5442,0.268238702,1.324694886,0.822750273,2.21159026,0.430718977,DB0047110013971_,0.842299428,0.281182159,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,143566,DB00722,10023644,50,25353,22,26010,0.000832429,2.331689574,1.385661071,4.044581643,0.004733458,DB0072210023644_,5.353099303,0.846593144,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,lisinopril,DB00722
,143568,DB00215,10039101,55,11048,12,5264,0.012253089,2.183715266,1.154229627,4.484254888,0.041852048,DB0021510039101_,3.173614541,0.781027677,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,143569,DB01068,10039101,52,13711,13,6827,0.02448364,1.991626756,1.068482088,3.989664669,0.072363682,DB0106810039101_,2.62605074,0.68895177,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,143582,DB00215,10047924,51,11052,11,5265,0.013879888,2.208600363,1.13550808,4.703798393,0.046236977,DB0021510047924_,3.073975428,0.792358995,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,143585,DB00641,10048865,39,14085,48,12427,0.132297105,0.716871519,0.457143691,1.117922555,0.259045694,DB0064110048865_,1.350750808,-0.332858647,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,simvastatin,DB00641
,143595,DB00722,10052140,40,25363,14,26018,0.000313732,2.930976889,1.560589326,5.833157089,0.002093803,DB0072210052140_,6.168773118,1.075335777,female,10052140,Eye pruritus,10015919,Eye disorders,Eye,lisinopril,DB00722
,143598,DB00484,10037844,45,2462,30,1750,0.814261959,1.066202514,0.654147177,1.760379808,0.900377586,DB0048410037844_,0.104941064,0.064103284,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,brimonidine,DB00484
,143603,DB00186,10013946,125,16776,50,9958,0.0184393,1.483944166,1.059850086,2.105493838,0.057941063,DB0018610013946_,2.848328947,0.39470352,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,143606,DB01593,10016256,110,1023,57,641,0.278295982,1.209072617,0.856210179,1.722079659,0.442114767,DB0159310016256_,0.816185776,0.189853634,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,zinc,DB01593
,143608,DB00829,10017885,54,7998,17,4437,0.046049162,1.762117142,1.004467295,3.246584714,0.117566144,DB0082910017885_,2.140754177,0.566516008,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,diazepam,DB00829
,143624,DB01593,10037087,50,1083,11,687,0.000728273,2.881973853,1.468116648,6.18311168,0.004229018,DB0159310037087_,5.465785365,1.058475425,female,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,zinc,DB01593
,143647,DB00169,10058467,41,38650,16,18159,0.572881088,1.203922334,0.660918154,2.298932681,0.722838872,DB0016910058467_,0.324568942,0.185584838,NA,10058467,Lung neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cholecalciferol,DB00169
,143654,DB00829,10061818,42,8010,14,4440,0.123050475,1.662858651,0.8890374,3.300730615,0.245806104,DB0082910061818_,1.403212248,0.5085382,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,143656,DB01611,10021097,131,11782,20,2341,0.321484453,1.301414857,0.807224134,2.205094553,0.489768386,DB0161110021097_,0.713822682,0.263452024,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,hydroxychloroquine,DB01611
,143669,DB00484,10047571,61,2446,41,1739,0.839120174,1.05776058,0.696844929,1.620074668,0.917558606,DB0048410047571_,0.086038826,0.056154013,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,brimonidine,DB00484
,143695,DB00028,10024264,38,13420,22,5593,0.255663113,0.719879145,0.414609269,1.279086523,0.416402077,DB0002810024264_,0.876103954,-0.328671935,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,143700,DB00196,10017533,94,4989,18,3267,1.35820630798025e-07,3.419292693,2.045499574,6.029653215,2.40245308245363e-06,DB0019610017533_,12.93902022,1.229433715,female,10017533,Fungal infection,10021881,Infections and infestations,Infec,fluconazole,DB00196
,143702,DB00196,10066901,18,5065,39,3246,8.80463900431262e-06,0.295829076,0.15900053,0.530647044,9.71578237734498e-05,DB0019610066901_,9.239173852,-1.217973439,male,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,143713,DB00482,10027599,81,8178,6,3065,2.6330043613802e-06,5.059295963,2.222849228,14.20755727,3.37355689197556e-05,DB0048210027599_,10.29695782,1.621227336,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,143746,DB00126,10017412,37,10134,17,5928,0.480791866,1.273150337,0.69845369,2.413382448,0.645550236,DB0012610017412_,0.437652247,0.241494409,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,ascorbic acid,DB00126
,143748,DB00437,10017412,36,6885,59,11487,0.915872968,1.018019099,0.652491562,1.56868563,0.96236383,DB0043710017412_,0.038362698,0.017858679,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,allopurinol,DB00437
,143768,DB08908,10008190,84,10589,45,3234,0.003322555,0.570127735,0.391441786,0.839988022,0.014692238,DB0890810008190_,4.220435925,-0.561894847,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,143773,DB00982,10000496,55,3309,36,2065,0.828635886,0.953444454,0.612715043,1.499919239,0.909933794,DB0098210000496_,0.094383436,-0.047674111,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,isotretinoin,DB00982
,143774,DB00795,10000087,45,4524,11,1492,0.438593779,1.349087934,0.684811435,2.900246226,0.606921239,DB0079510000087_,0.499356252,0.29942876,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,sulfasalazine,DB00795
,143775,DB00795,10047700,109,4460,26,1477,0.157566583,1.388252761,0.894224674,2.228624954,0.294244442,DB0079510047700_,1.223344423,0.32804595,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sulfasalazine,DB00795
,143780,DB00264,10037437,34,29573,40,24852,0.161615688,0.714317592,0.438425323,1.157811435,0.299602819,DB0026410037437_,1.20529762,-0.336427609,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,143782,DB00695,10037437,45,28004,32,20496,1,1.029230031,0.639505501,1.674083203,1,DB0069510037437_,0,0.02881098,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,143784,DB00996,10037437,40,38913,40,22385,0.014480435,0.575291455,0.361569864,0.915147156,0.047900609,DB0099610037437_,3.038627064,-0.552878488,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,143785,DB01373,10037437,40,22680,23,7358,0.038669782,0.564235217,0.329507694,0.987944046,0.102966644,DB0137310037437_,2.273350188,-0.572284063,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,143790,DB00727,10043607,32,3811,29,4144,0.521150021,1.199836419,0.701557016,2.059987741,0.680064167,DB0072710043607_,0.385568122,0.18218523,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,nitroglycerin,DB00727
,143791,DB14513,10043607,76,7101,53,3511,0.059906033,0.70900573,0.491505382,1.029292346,0.143297999,DB1451310043607_,1.942828906,-0.343891671,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,magnesium,DB14513
,143818,DB11089,10008469,79,10096,32,8375,0.000519041,2.047807263,1.340725047,3.195277203,0.003183898,DB1108910008469_,5.749649048,0.716769593,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,143876,DB00169,10041823,33,38658,28,18147,0.026970435,0.553286529,0.324108739,0.950617176,0.077951037,DB0016910041823_,2.551674375,-0.591879277,NA,10041823,Squamous cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cholecalciferol,DB00169
,143888,DB00169,10048706,57,38634,7,18168,0.000133048,3.828780943,1.742676615,9.953876051,0.001016914,DB0016910048706_,6.89098272,1.342546461,female,10048706,Joint range of motion decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,143907,DB00008,10033371,61,1464,46,1630,0.049523148,1.4762569,0.983436064,2.229353005,0.124085215,DB0000810033371_,2.086786732,0.389509763,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,peginterferon alfa-2a,DB00008
,143922,DB00169,10021639,50,38641,14,18161,0.106501272,1.678532485,0.913278148,3.288776356,0.220850138,DB0016910021639_,1.510270915,0.517919891,NA,10021639,Incontinence,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,143930,DB00982,10047513,49,3315,22,2079,0.220061424,1.396750531,0.825897337,2.433474073,0.373518955,DB0098210047513_,0.984786526,0.334148489,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,isotretinoin,DB00982
,143934,DB00678,10041466,35,15564,27,10697,0.698450374,0.890938667,0.523631604,1.531382892,0.818692416,DB0067810041466_,0.200046826,-0.11547969,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,losartan,DB00678
,143938,DB00661,10046571,63,3465,14,1581,0.01281509,2.052999939,1.133610087,3.980300858,0.043396628,DB0066110046571_,3.137373528,0.719302109,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,verapamil,DB00661
,143939,DB00193,10049848,123,19197,60,8642,0.630747313,0.922862762,0.67170532,1.279853385,0.769617744,DB0019310049848_,0.261861323,-0.080274742,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,143941,DB00736,10049848,50,10541,27,5526,0.904651616,0.970789873,0.59552174,1.6146288,0.957604967,DB0073610049848_,0.043319938,-0.029645237,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,143952,DB00211,10025482,54,1382,51,1580,0.370745504,1.210442753,0.804209174,1.824079986,0.540430656,DB0021110025482_,0.615388947,0.190986204,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,midodrine,DB00211
,143957,DB01076,10033295,67,25680,80,25503,0.283346287,0.831731701,0.59177908,1.165857642,0.447689177,DB0107610033295_,0.803656088,-0.184245365,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,143958,DB00211,10040047,31,1405,39,1592,0.717036669,0.900713273,0.54024048,1.490238142,0.832718627,DB0021110040047_,0.183059477,-0.104568304,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,midodrine,DB00211
,143981,DB00316,10067585,51,65423,35,36918,0.370969172,0.822273414,0.524349637,1.302988396,0.540636764,DB0031610067585_,0.615007641,-0.195682319,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,144012,DB01156,10067482,60,13562,24,6304,0.638494573,1.162052287,0.712113295,1.953165248,0.775690046,DB0115610067482_,0.254002264,0.150187655,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,144013,DB08910,10028836,31,16713,31,17457,0.899280065,1.044530416,0.613783248,1.777573775,0.956490275,DB0891010028836_,0.044484657,0.043567422,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pomalidomide,DB08910
,144022,DB00682,10043521,79,19380,26,16338,1.22556095454406e-05,2.561380593,1.625333575,4.160486278,0.000129764,DB0068210043521_,8.949794486,0.940546407,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,warfarin,DB00682
,144023,DB00820,10043521,99,11816,31,5785,0.030777777,1.563494244,1.03378815,2.42532255,0.086435586,DB0082010043521_,2.448355814,0.446923216,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,144024,DB00005,10033733,109,127973,40,42379,0.570191235,0.90238831,0.622681207,1.331289691,0.720856239,DB0000510033733_,0.327315553,-0.102710353,NA,10033733,Papule,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,144058,DB00996,10048439,180,38773,21,22404,4.6600829371186e-17,4.952194232,3.142603801,8.199289551,3.5868310395948e-15,DB0099610048439_,33.2615073,1.599830758,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,144065,DB00996,10057667,40,38913,25,22400,0.79687343,0.921031478,0.545030862,1.584535724,0.89005462,DB0099610057667_,0.116472448,-0.082261065,NA,10057667,Bipolar disorder,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,144077,DB00374,10052270,101,17615,23,5701,0.142274565,1.421177831,0.895676131,2.345375709,0.272969849,DB0037410052270_,1.298393933,0.351485986,NA,10052270,Catheter site pruritus,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,144114,DB00390,10035528,51,4094,34,3267,0.443739684,1.19696643,0.758578655,1.910161124,0.611785869,DB0039010035528_,0.491372945,0.179790381,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,digoxin,DB00390
,144119,DB08895,10060795,260,27854,72,6574,0.233330782,0.852315334,0.65316755,1.124082295,0.389908279,DB0889510060795_,0.94184375,-0.15979871,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,tofacitinib,DB08895
,144122,DB01136,10019301,38,9846,37,11078,0.563412047,1.155526303,0.714590285,1.870019731,0.71536668,DB0113610019301_,0.334960029,0.144555914,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,carvedilol,DB01136
,144134,DB00381,10000486,23,29337,51,22836,1.69604593409751e-05,0.351050534,0.204712438,0.585124402,0.000172692,DB0038110000486_,8.663998035,-1.046825094,male,10000486,Acidosis,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,144194,DB11365,10003988,58,1587,37,1511,0.061245774,1.492306989,0.964940738,2.333518489,0.14572691,DB1136510003988_,1.926020887,0.400323238,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sennosides,DB11365
,144195,DB00653,10013709,43,1049,40,782,0.364645363,0.801481586,0.503422389,1.278492013,0.534279293,DB0065310013709_,0.626836557,-0.221293282,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,magnesium sulfate,DB00653
,144198,DB01610,10013709,22,919,53,1165,0.01247362,0.526361171,0.302475526,0.888002896,0.042456341,DB0161010013709_,3.159278997,-0.641767665,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,valganciclovir,DB01610
,144199,DB11365,10013709,38,1607,36,1512,1,0.993156652,0.60922462,1.621768574,1,DB1136510013709_,0,-0.006866871,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sennosides,DB11365
,144210,DB00316,10021058,36,65438,27,36926,0.293855837,0.752409041,0.444113714,1.288754057,0.459570457,DB0031610021058_,0.777463015,-0.284475165,NA,10021058,Hypophosphataemia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,144329,DB00203,10003246,67,13811,30,8908,0.117433918,1.44046205,0.922576033,2.297572705,0.237305443,DB0020310003246_,1.43840718,0.36496393,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,144330,DB08932,10003246,135,19308,26,6571,0.006249633,1.766945974,1.15366789,2.80514091,0.024456096,DB0893210003246_,3.710875769,0.569252618,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,144331,DB00203,10027175,140,13738,81,8857,0.488751924,1.114328099,0.840426622,1.485722996,0.652262546,DB0020310027175_,0.42730812,0.108251622,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,144332,DB08932,10027175,292,19151,66,6531,0.002173921,1.508713374,1.149691119,2.00507353,0.010421577,DB0893210027175_,4.563876914,0.411257218,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,144361,DB00497,10020646,39,19228,47,16328,0.128904154,0.70465045,0.448529242,1.101400318,0.254019995,DB0049710020646_,1.370342297,-0.350053415,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,144394,DB00316,10021518,45,65429,13,36940,0.029107028,1.954306885,1.035885257,3.949820957,0.082724574,DB0031610021518_,2.49223858,0.670035596,NA,10021518,Impaired gastric emptying,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,144409,DB00433,10028334,86,7570,72,5948,0.688011312,0.938534868,0.676905779,1.304496059,0.811905241,DB0043310028334_,0.208371644,-0.06343527,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,prochlorperazine,DB00433
,144411,DB01306,10028334,56,4152,49,3817,0.844402159,1.050655028,0.701282102,1.578559943,0.921373327,DB0130610028334_,0.081889975,0.049413805,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin aspart,DB01306
,144486,DB08932,10052268,206,19237,41,6556,0.001175595,1.712202237,1.218161313,2.459442501,0.006295309,DB0893210052268_,5.067950484,0.5377804,NA,10052268,Catheter site pain,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,144487,DB08932,10056520,124,19319,24,6573,0.010207663,1.7577563,1.127560179,2.849522663,0.036150422,DB0893210056520_,3.320066647,0.564038166,NA,10056520,Catheter site infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,144488,DB00564,10018100,44,2560,35,1428,0.124741688,0.701341364,0.437426556,1.131942694,0.248189787,DB0056410018100_,1.393561555,-0.354760543,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,carbamazepine,DB00564
,144504,DB14126,10016256,40,931,40,1236,0.250340593,1.327421116,0.827301272,2.129920002,0.410086024,DB1412610016256_,0.891388328,0.283238049,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tenofovir,DB14126
,144506,DB09053,10034474,16,2269,39,4013,0.324641923,0.725622914,0.377649268,1.332313555,0.493135283,DB0905310034474_,0.706971734,-0.320724801,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,ibrutinib,DB09053
,144526,DB01075,10005911,48,19900,35,11062,0.251251274,0.762375655,0.482642431,1.215138111,0.411203869,DB0107510005911_,0.888666157,-0.271315859,NA,10005911,Body temperature increased,10022891,Investigations,Inv,diphenhydramine,DB01075
,144529,DB00996,10024570,57,38896,25,22400,0.301750208,1.313034223,0.806973165,2.193977099,0.468073427,DB0099610024570_,0.7591301,0.272340659,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,144531,DB00996,10033557,232,38721,56,22369,3.65754237409306e-10,2.393281338,1.779808129,3.266143163,1.09809824446643e-08,DB0099610033557_,18.32710093,0.872665369,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,gabapentin,DB00996
,144564,DB00007,10003988,32,1915,113,4339,0.028197544,0.641682041,0.417620993,0.961482293,0.080689397,DB0000710003988_,2.517148105,-0.443662361,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,leuprolide,DB00007
,144566,DB00927,10013573,278,7219,124,4892,0.000102041,1.519211454,1.221027276,1.898951695,0.000812157,DB0092710013573_,7.115817029,0.41819142,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,144593,DB00007,10033425,42,1905,78,4374,0.271811439,1.236260675,0.82535773,1.829387973,0.434667341,DB0000710033425_,0.833174274,0.212091239,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,leuprolide,DB00007
,144614,DB00836,10049848,41,5494,18,4057,0.06548066,1.68191486,0.943275947,3.115258688,0.153278043,DB0083610049848_,1.875501734,0.519932942,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,144615,DB00927,10049848,43,7454,26,4990,0.713557031,1.107163289,0.664048314,1.879586739,0.830069995,DB0092710049848_,0.186245251,0.101801149,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,144616,DB06643,10049848,111,52310,23,7492,0.115810349,0.691214652,0.437849687,1.136009899,0.23490952,DB0664310049848_,1.448554859,-0.369304864,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,144618,DB00836,10051398,29,5506,46,4029,0.001371668,0.461351818,0.278965297,0.751683499,0.007144012,DB0083610051398_,4.941480703,-0.773594364,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,loperamide,DB00836
,144619,DB00927,10051398,38,7459,41,4975,0.037699966,0.618218803,0.38632639,0.987009036,0.101013621,DB0092710051398_,2.292499913,-0.480912834,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,famotidine,DB00927
,144621,DB00115,10018838,60,18365,27,10445,0.371590154,1.263897146,0.789467843,2.072266148,0.541241672,DB0011510018838_,0.613889387,0.234199921,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,144622,DB00158,10018838,48,16767,26,8078,0.62099865,0.889448871,0.540423285,1.494664136,0.761455906,DB0015810018838_,0.272523013,-0.117153254,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,folic acid,DB00158
,144626,DB08932,10018838,102,19341,27,6570,0.265911889,1.283260328,0.831896569,2.042714981,0.427976242,DB0893210018838_,0.848687595,0.249403971,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,macitentan,DB08932
,144629,DB01373,10018852,42,22678,8,7373,0.189259282,1.706772829,0.791161361,4.21112838,0.335616814,DB0137310018852_,1.091785203,0.534604353,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,calcium,DB01373
,144633,DB00158,10018884,209,16606,155,7949,5.90702629743565e-05,0.64545007,0.520935601,0.801156101,0.000509236,DB0015810018884_,7.582598158,-0.437807422,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,folic acid,DB00158
,144634,DB00165,10018884,35,2110,27,1339,0.511362028,0.822679785,0.481307654,1.420222537,0.6717049,DB0016510018884_,0.397936172,-0.195188236,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,pyridoxine,DB00165
,144635,DB01611,10018884,73,11840,10,2351,0.302913946,1.449481594,0.74360585,3.15353147,0.46931084,DB0161110018884_,0.756489958,0.371205971,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,hydroxychloroquine,DB01611
,144636,DB00390,10022437,68,4077,37,3264,0.06063378,1.471275359,0.969010841,2.265437189,0.144591419,DB0039010022437_,1.933843312,0.386129616,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,digoxin,DB00390
,144637,DB08932,10022437,418,19025,103,6494,0.003117732,1.385199507,1.111862636,1.73902707,0.013964359,DB0893210022437_,4.271246982,0.325844178,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,macitentan,DB08932
,144641,DB08932,10038153,72,19371,26,6571,0.815982696,0.939371007,0.591862155,1.534310882,0.901351313,DB0893210038153_,0.103860183,-0.062544769,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,macitentan,DB08932
,144642,DB14513,10038153,43,7134,19,3545,0.786963038,1.124581623,0.640389877,2.046604793,0.884476968,DB1451310038153_,0.122758806,0.117411076,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,magnesium,DB14513
,144680,DB01203,10028813,39,660,19,486,0.172760063,1.510982309,0.840317629,2.804664878,0.314473564,DB0120310028813_,1.156855265,0.412759975,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,nadolol,DB01203
,144681,DB06684,10028813,65,682,13,322,0.004811571,2.359116984,1.264870177,4.735545282,0.019848108,DB0668410028813_,3.919646604,0.85828739,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,vilazodone,DB06684
,144685,DB00736,10038153,35,10556,18,5535,1,1.019561557,0.56142173,1.914154689,1,DB0073610038153_,0,0.019372689,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,esomeprazole,DB00736
,144704,DB00480,10015926,31,67397,24,67638,0.348786657,1.296279304,0.736271072,2.308436504,0.518309435,DB0048010015926_,0.657182851,0.259498087,NA,10015926,Eye haemorrhage,10015919,Eye disorders,Eye,lenalidomide,DB00480
,144705,DB01234,10027940,31,31594,19,32869,0.088491354,1.697396424,0.928840543,3.180891993,0.19272477,DB0123410027940_,1.646492169,0.529095562,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,144720,DB00213,10003553,121,18774,21,13400,7.65665681609293e-12,4.112405752,2.571707599,6.888244263,2.981558880163e-10,DB0021310003553_,21.93340465,1.414008198,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,144723,DB00268,10011224,68,2907,23,1522,0.074419344,1.547788925,0.947839502,2.61380967,0.168870588,DB0026810011224_,1.778622607,0.436827413,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ropinirole,DB00268
,144727,DB00169,10014011,126,38565,31,18144,0.000784105,1.912247577,1.281769692,2.933042339,0.004499554,DB0016910014011_,5.403776958,0.648279292,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,144739,DB00635,10023215,48,33005,15,23779,0.00319463,2.305441255,1.268713615,4.433650452,0.01424321,DB0063510023215_,4.251474998,0.835272092,NA,10023215,Joint effusion,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,144755,DB00213,10036790,99,18796,37,13384,0.00062687,1.905213963,1.292829051,2.861935763,0.003737189,DB0021310036790_,5.589421554,0.644594319,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,144758,DB00213,10040753,273,18622,72,13349,3.92259161087823e-16,2.717912503,2.087210623,3.578181584,2.74581412761476e-14,DB0021310040753_,31.22611369,0.999864123,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,144759,DB00268,10040753,52,2923,15,1530,0.050643829,1.814359164,1.001910759,3.481829153,0.126172577,DB0026810040753_,2.070104652,0.595732328,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,ropinirole,DB00268
,144763,DB00425,10047461,35,12660,17,7467,0.567325386,1.21425982,0.661757337,2.31310333,0.718501904,DB0042510047461_,0.330586924,0.19413469,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,zolpidem,DB00425
,144790,DB00635,10060968,42,33011,11,23783,0.001891866,2.750741636,1.391523315,5.925619898,0.009293223,DB0063510060968_,4.678469874,1.011870561,female,10060968,Arthritis infective,10021881,Infections and infestations,Infec,prednisone,DB00635
,144794,DB00169,10062060,114,38577,37,18138,0.054238479,1.448653361,0.991435054,2.160827642,0.132916132,DB0016910062060_,2.018036936,0.370634408,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,144797,DB00635,10062060,45,33008,19,23775,0.0566405,1.705905724,0.977515004,3.089279894,0.137197212,DB0063510062060_,1.986335884,0.534096186,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,144803,DB01261,10038435,48,3733,61,3242,0.052991541,0.683429649,0.456826187,1.017330126,0.130615403,DB0126110038435_,2.035498126,-0.380631556,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,sitagliptin,DB01261
,144808,DB00008,10003549,60,1465,38,1638,0.007336346,1.765073316,1.148756747,2.741613769,0.027792152,DB0000810003549_,3.583001603,0.568192228,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,peginterferon alfa-2a,DB00008
,144830,DB00814,10006451,93,8194,21,3394,0.009615265,1.834256027,1.130779095,3.107601275,0.034498668,DB0081410006451_,3.366834557,0.606638964,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,meloxicam,DB00814
,144834,DB00448,10020751,51,5094,20,3104,0.10967748,1.553749533,0.908155103,2.756939284,0.225585709,DB0044810020751_,1.489055108,0.440671063,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,lansoprazole,DB00448
,144839,DB00996,10022687,68,38885,32,22393,0.405806839,1.223780965,0.792489017,1.926134066,0.575377337,DB0099610022687_,0.552729216,0.201945218,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,144851,DB00448,10047924,36,5109,15,3109,0.247830776,1.460417702,0.77836177,2.87601982,0.407150651,DB0044810047924_,0.898572012,0.378722492,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lansoprazole,DB00448
,144863,DB00370,10048959,43,4498,37,3626,0.821488853,0.936884635,0.588176511,1.498798566,0.904892846,DB0037010048959_,0.099938745,-0.065195126,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,144879,DB05676,10040742,32,47097,18,25311,0.882735462,0.955427348,0.520231646,1.808194854,0.951043643,DB0567610040742_,0.050195326,-0.045596554,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,144884,DB00177,10068319,36,4764,15,2835,0.30900059,1.428148155,0.761025155,2.81293621,0.47634042,DB0017710068319_,0.741622512,0.356378609,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,valsartan,DB00177
,144903,DB00619,10030124,42,2857,30,2464,0.476217999,1.207377581,0.735441472,2.004469566,0.641621308,DB0061910030124_,0.443757012,0.188450719,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,144905,DB00619,10061428,33,2866,31,2463,0.801134348,0.914845704,0.541426436,1.549415532,0.892412703,DB0061910061428_,0.113826582,-0.088999858,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,imatinib,DB00619
,144907,DB00710,10037660,54,2352,6,195,0.460962609,0.746270883,0.31587639,2.149864199,0.628264871,DB0071010037660_,0.464793432,-0.292666631,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ibandronate,DB00710
,144932,DB01175,10045555,42,10682,13,4879,0.246050052,1.475631293,0.776187591,2.998977645,0.404986106,DB0117510045555_,0.903902517,0.389085893,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,144933,DB00455,10070863,56,9345,42,5076,0.136947171,0.724281447,0.476090417,1.109340882,0.265425436,DB0045510070863_,1.326421321,-0.322575223,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,144934,DB01062,10070863,36,4450,39,1706,1.21394639278184e-05,0.353949305,0.217846054,0.573716029,0.000128716,DB0106210070863_,8.95790575,-1.038601583,male,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,oxybutynin,DB01062
,144945,DB00472,10010144,938,9821,304,4008,0.000730245,1.259161624,1.099293165,1.445340001,0.004238601,DB0047210010144_,5.463522111,0.230446121,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,144951,DB00497,10040984,55,19212,42,16333,0.611886371,1.113256608,0.731111237,1.706191278,0.753852039,DB0049710040984_,0.282559165,0.107289601,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,144952,DB01104,10040984,48,15415,29,7257,0.327453436,0.779251154,0.481058842,1.282657702,0.495875094,DB0110410040984_,0.701431211,-0.24942188,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,144955,DB00181,10016334,42,9814,14,5857,0.070965301,1.790339047,0.957472161,3.55264988,0.162993522,DB0018110016334_,1.814044818,0.582405013,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,144977,DB00421,10008190,72,8831,52,5200,0.263970394,0.815331766,0.561824872,1.19025116,0.425855386,DB0042110008190_,0.85365546,-0.204160174,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,144984,DB00490,10008531,46,4024,17,1559,1,1.048302329,0.587549809,1.956724738,1,DB0049010008531_,0,0.047172026,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,144989,DB00490,10028411,41,4029,16,1560,1,0.992182973,0.542955307,1.899881018,1,DB0049010028411_,0,-0.00784774,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,buspirone,DB00490
,144991,DB00490,10037660,73,3997,32,1544,0.583037821,0.881254273,0.571483614,1.386240056,0.731134245,DB0049010037660_,0.31315819,-0.126409076,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,144994,DB00316,10073133,25,65449,32,36921,0.002204785,0.440716076,0.250351074,0.767679453,0.010529208,DB0031610073133_,4.553602137,-0.819354429,NA,10073133,Plasma cell myeloma recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,145014,DB01118,10037313,8,3055,57,4652,2.34022787633857e-06,0.213751448,0.087948444,0.451108285,3.03692370918584e-05,DB0111810037313_,10.4020804,-1.542941398,male,10037313,Pulmonary alveolar haemorrhage,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,145019,DB06228,10038435,67,15845,78,15998,0.406199694,0.867273164,0.61574969,1.218747046,0.575763534,DB0622810038435_,0.552058234,-0.142401284,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,rivaroxaban,DB06228
,145020,DB00343,10043607,78,8658,45,5050,1,1.011010419,0.690494804,1.495954212,1,DB0034310043607_,0,0.010950246,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,diltiazem,DB00343
,145031,DB00421,10005750,65,8838,31,5221,0.342397687,1.238672011,0.794573846,1.968927232,0.511722713,DB0042110005750_,0.669972377,0.214039847,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,spironolactone,DB00421
,145042,DB05676,10016338,62,47067,28,25301,0.507301138,1.190268732,0.750112651,1.932551888,0.66793951,DB0567610016338_,0.403557663,0.174179107,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,145048,DB00338,10012218,52,33622,43,22229,0.294803209,0.799534989,0.523342527,1.227201892,0.460709435,DB0033810012218_,0.774987728,-0.223724984,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,145055,DB00404,10070863,1185,18707,953,8909,3.95853720337499e-30,0.592171355,0.54129805,0.648013447,8.89317524706938e-28,DB0040410070863_,62.28709845,-0.523959234,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,145057,DB00243,10011078,22,1232,50,1576,0.029634756,0.562967716,0.322747533,0.952919552,0.083893329,DB0024310011078_,2.47820918,-0.574532996,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,ranolazine,DB00243
,145058,DB08827,10013573,39,1123,14,568,0.303674189,1.408720074,0.740893445,2.83321199,0.470225393,DB0882710013573_,0.754543139,0.342681543,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lomitapide,DB08827
,145062,DB00181,10019196,46,9810,13,5858,0.014893172,2.11288451,1.121287168,4.26664171,0.049034511,DB0018110019196_,3.015230919,0.74805408,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,145063,DB00230,10019196,82,19592,22,8629,0.042145688,1.641594978,1.014392841,2.762929169,0.109977109,DB0023010019196_,2.207483037,0.495668317,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,145080,DB00115,10033557,153,18272,35,10437,1.62251005069595e-07,2.496896135,1.718649815,3.718712724,2.81595752278264e-06,DB0011510033557_,12.7802082,0.915048414,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,cyanocobalamin,DB00115
,145083,DB01611,10033557,77,11836,9,2352,0.145793327,1.700062902,0.848972537,3.863599265,0.278177816,DB0161110033557_,1.279494743,0.530665251,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,hydroxychloroquine,DB01611
,145085,DB06228,10033557,119,15793,32,16044,2.60661207243724e-13,3.777365442,2.536820669,5.773566916,1.27232680267433e-11,DB0622810033557_,25.08758867,1.329026793,female,10033557,Palpitations,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,145087,DB00620,10046571,97,4731,18,3114,3.84871939879859e-08,3.546553099,2.124812358,6.247831327,7.60639201185504e-07,DB0062010046571_,14.0891067,1.265976174,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,triamcinolone,DB00620
,145089,DB00480,10047513,362,67066,253,67409,8.43556638366117e-06,1.438137041,1.22091501,1.696062802,9.35959739951599e-05,DB0048010047513_,9.276523188,0.363348555,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,lenalidomide,DB00480
,145090,DB00656,10047513,93,11920,35,6584,0.052129723,1.467641544,0.98390093,2.234082392,0.129023519,DB0065610047513_,2.047760574,0.38365672,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,trazodone,DB00656
,145095,DB00169,10025650,44,38647,28,18147,0.208015528,0.737858179,0.449061665,1.231212119,0.358831051,DB0016910025650_,1.02490361,-0.304003643,NA,10025650,Malignant melanoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cholecalciferol,DB00169
,145102,DB00497,10010144,1489,17778,806,15569,2.12100589174068e-27,1.617818387,1.479948047,1.769593645,3.93997454872111e-25,DB0049710010144_,56.19345306,0.481078567,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,145103,DB00956,10010144,426,5388,218,3249,0.057504096,1.178298167,0.992564083,1.401880297,0.138752024,DB0095610010144_,1.97506694,0.164071166,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,hydrocodone,DB00956
,145106,DB00829,10070863,686,7366,504,3950,4.77732852241338e-07,0.729937595,0.645449325,0.825828213,7.45013825046785e-06,DB0082910070863_,11.80727797,-0.314796235,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,145117,DB00047,10043607,55,9230,41,8477,0.356714521,1.232008498,0.806398139,1.89564249,0.526375431,DB0004710043607_,0.641740574,0.208645763,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,insulin glargine,DB00047
,145118,DB00115,10043607,194,18231,137,10335,0.050743138,0.802770793,0.64081232,1.007857326,0.126389022,DB0011510043607_,2.068390652,-0.219686044,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,cyanocobalamin,DB00115
,145119,DB00158,10043607,88,16727,84,8020,8.76859674789818e-06,0.502294678,0.367771147,0.686446073,9.68414140834049e-05,DB0015810043607_,9.242435824,-0.688568323,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,folic acid,DB00158
,145124,DB00193,10048439,90,19230,7,8695,1.66618830666841e-08,5.813505167,2.707037907,14.88460787,3.55196752966579e-07,DB0019310048439_,14.85059397,1.760183688,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,145134,DB00169,10051118,60,38631,28,18147,1,1.006613318,0.632459489,1.638229643,1,DB0016910051118_,0,0.006591546,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,145135,DB00193,10051118,53,19267,21,8681,0.706338487,1.137124955,0.673883687,1.986054497,0.824153019,DB0019310051118_,0.193399064,0.128503108,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,145137,DB00316,10051118,173,65301,62,36891,0.001724455,1.576351438,1.172612309,2.143062398,0.008603457,DB0031610051118_,4.75559122,0.45511296,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,145138,DB00338,10051118,61,33613,29,22243,0.161224905,1.391923313,0.880455123,2.247506328,0.299120991,DB0033810051118_,1.206907135,0.330686469,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,145141,DB00635,10051118,86,32967,55,23739,0.549831872,1.125983542,0.793170056,1.610139791,0.704184509,DB0063510051118_,0.350714871,0.118656913,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,145153,DB05676,10037884,144,46985,80,25249,0.833342921,0.967263114,0.730631709,1.288337602,0.913407226,DB0567610037884_,0.090573467,-0.033284728,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,145158,DB00005,10054112,465,127617,199,42220,0.002959928,0.773054894,0.653147054,0.917676903,0.013353076,DB0000510054112_,4.316008494,-0.257405219,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,145162,DB00230,10038743,70,19604,20,8631,0.107753295,1.540923217,0.925767513,2.676310749,0.222712505,DB0023010038743_,1.501873553,0.432381728,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,145163,DB00285,10038743,38,10913,16,3702,0.437983225,0.805667224,0.438044458,1.549649692,0.606425889,DB0028510038743_,0.500172752,-0.216084495,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,145164,DB00598,10016256,67,1521,38,990,0.54166306,1.147518646,0.752899065,1.771277755,0.697033856,DB0059810016256_,0.360921296,0.137601912,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,labetalol,DB00598
,145165,DB11750,10016256,88,2412,44,1469,0.315862832,1.217987122,0.833544639,1.802103543,0.483501996,DB1175010016256_,0.726699835,0.197199596,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,clobetasol,DB11750
,145181,DB00480,10049414,43,67385,39,67623,0.66027365,1.106451582,0.700388511,1.752796686,0.792569604,DB0048010049414_,0.232474949,0.101158121,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,145185,DB00264,10000880,26,29581,40,24852,0.018253966,0.546099994,0.319899659,0.917422031,0.057482389,DB0026410000880_,2.856276665,-0.60495318,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metoprolol,DB00264
,145187,DB01137,10000880,25,7747,59,5534,1.67189557704704e-07,0.302713327,0.181410001,0.491600163,2.89307276120352e-06,DB0113710000880_,12.75319138,-1.194969037,male,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levofloxacin,DB01137
,145190,DB00207,10016288,34,9046,22,5433,0.783616954,0.928200944,0.526726062,1.667757139,0.882171087,DB0020710016288_,0.125369266,-0.074507035,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,azithromycin,DB00207
,145191,DB01373,10016288,39,22681,26,7355,0.005704736,0.486416986,0.288487492,0.832849661,0.022737962,DB0137310016288_,3.783719426,-0.720689026,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,calcium,DB01373
,145193,DB00207,10033661,32,9048,21,5434,0.77711444,0.915168461,0.511100283,1.671688654,0.878512755,DB0020710033661_,0.129524852,-0.08864712,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,azithromycin,DB00207
,145195,DB00158,10002198,52,16763,13,8091,0.033359525,1.930635618,1.035899812,3.867373013,0.09205828,DB0015810002198_,2.385333429,0.657849285,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,folic acid,DB00158
,145203,DB00654,10002855,32,3784,22,2576,1,0.990197729,0.55634556,1.792989526,1,DB0065410002855_,0,-0.009850629,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,latanoprost,DB00654
,145204,DB04861,10002855,36,1929,21,1366,0.501645222,1.213878747,0.686304367,2.198847227,0.663150083,DB0486110002855_,0.410753945,0.193820809,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,nebivolol,DB04861
,145218,DB00175,10015150,63,8068,37,6069,0.264855748,1.2808031,0.839006326,1.980331043,0.426812173,DB0017510015150_,0.851411239,0.247487303,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,pravastatin,DB00175
,145220,DB00588,10015150,162,16362,56,8412,0.009642445,1.487247969,1.089878562,2.05550745,0.034574951,DB0058810015150_,3.364625824,0.396927411,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,145234,DB01261,10030095,33,3748,22,3281,0.344863401,1.31304828,0.741197327,2.369149239,0.514311177,DB0126110030095_,0.664926794,0.272351365,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,145236,DB00688,10051358,85,6405,87,5291,0.165657564,0.80710132,0.590058153,1.103685467,0.305019723,DB0068810051358_,1.187378838,-0.214306067,NA,10051358,Post transplant lymphoproliferative disorder,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,mycophenolate mofetil,DB00688
,145251,DB00904,10031127,31,23038,37,14419,0.008546214,0.524381445,0.314469523,0.8690819,0.031393647,DB0090410031127_,3.461149729,-0.64553591,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,ondansetron,DB00904
,145252,DB00996,10031127,71,38882,46,22379,0.564472647,0.8883723,0.604294851,1.317340394,0.71628014,DB0099610031127_,0.333683931,-0.118364367,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,gabapentin,DB00996
,145263,DB00537,10047513,54,7503,26,4272,0.559914383,1.18249899,0.726534057,1.970346619,0.712566552,DB0053710047513_,0.338881965,0.167629988,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ciprofloxacin,DB00537
,145264,DB00904,10047513,164,22905,67,14389,0.002785552,1.537674382,1.149597643,2.076558383,0.012723647,DB0090410047513_,4.364293049,0.430271134,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ondansetron,DB00904
,145301,DB00019,10061428,74,18938,53,9476,0.047959566,0.698616426,0.483947348,1.014603861,0.121271494,DB0001910061428_,2.109723495,-0.358653434,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,pegfilgrastim,DB00019
,145304,DB04861,10061428,37,1928,29,1358,0.705686694,0.898692375,0.53490377,1.52311752,0.82366673,DB0486110061428_,0.193989285,-0.106814489,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,nebivolol,DB04861
,145308,DB00559,10052915,37,9622,19,3287,0.165862802,0.665269443,0.372316033,1.226529386,0.305308099,DB0055910052915_,1.186433851,-0.407563143,NA,10052915,Catheter placement,10042613,Surgical and medical procedures,Surg,bosentan,DB00559
,145312,DB00472,10016807,37,10722,26,4286,0.035037587,0.568897594,0.334834808,0.979732341,0.095469358,DB0047210016807_,2.348949943,-0.564054836,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,fluoxetine,DB00472
,145314,DB00813,10016807,38,10534,12,10156,0.000339963,3.053156858,1.560629977,6.420858338,0.002238736,DB0081310016807_,6.101843685,1.116176091,female,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,fentanyl,DB00813
,145318,DB00813,10017955,35,10537,40,10128,0.488599604,0.841044587,0.518248491,1.359175549,0.652152571,DB0081310017955_,0.427476739,-0.173110604,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,145320,DB00030,10021097,35,2171,24,1797,0.512245645,1.207048409,0.694947441,2.129651231,0.672462319,DB0003010021097_,0.3968092,0.188178048,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,insulin human,DB00030
,145324,DB00472,10030095,56,10703,10,4302,0.013751621,2.250783728,1.136397513,4.953304984,0.045879465,DB0047210030095_,3.081737652,0.811278479,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,145329,DB00030,10061428,40,2166,25,1796,0.315175086,1.326591738,0.78186291,2.291226566,0.482773673,DB0003010061428_,0.728207321,0.28261305,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,insulin human,DB00030
,145333,DB00203,10039117,37,13841,18,8920,0.406820719,1.324710659,0.734772675,2.473317063,0.576333006,DB0020310039117_,0.551069649,0.281194065,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,145341,DB00213,10047340,71,18824,18,13403,3.21597205453806e-05,2.808384981,1.655147665,5.009562056,0.000301684,DB0021310047340_,8.106130817,1.032609578,female,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,pantoprazole,DB00213
,145365,DB01202,10000087,51,6663,12,5706,1.05207762357709e-05,3.639132947,1.911730153,7.506821815,0.000113428,DB0120210000087_,9.084338163,1.291745452,female,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,levetiracetam,DB01202
,145379,DB01104,10001488,63,15400,61,7225,6.76542516579886e-05,0.484541779,0.33486404,0.701519651,0.000570148,DB0110410001488_,7.469614361,-0.72455162,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,145381,DB01104,10001497,118,15345,105,7181,3.22155800297083e-06,0.525902713,0.400252028,0.691829257,4.03260113080717e-05,DB0110410001497_,10.11851386,-0.64263904,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,145386,DB01104,10012239,47,15416,46,7240,0.000496276,0.479856267,0.312342521,0.737563095,0.003072575,DB0110410012239_,5.785239388,-0.734268663,NA,10012239,Delusion,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,145420,DB00421,10012601,34,8869,18,5234,0.774880165,1.114727857,0.611410059,2.098764144,0.877304578,DB0042110012601_,0.130901052,0.1086103,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,spironolactone,DB00421
,145425,DB01136,10012601,44,9840,50,11065,1,0.989552721,0.644015292,1.515798317,1,DB0113610012601_,0,-0.010502235,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,carvedilol,DB01136
,145429,DB00121,10013573,181,4042,21,447,0.810391367,0.953169526,0.597512115,1.594239337,0.897967544,DB0012110013573_,0.107621354,-0.047962505,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,biotin,DB00121
,145433,DB01390,10013573,35,1374,31,1486,0.455986892,1.220977607,0.726863626,2.059845707,0.623389239,DB0139010013573_,0.472584173,0.199651855,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sodium bicarbonate,DB01390
,145459,DB00188,10030095,31,7855,28,8800,0.434979718,1.240318368,0.719134263,2.14812775,0.603395619,DB0018810030095_,0.505182213,0.215368095,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,145463,DB01377,10030095,35,3761,17,2653,0.25779126,1.452207185,0.790091678,2.770418372,0.418661926,DB0137710030095_,0.870691543,0.373084595,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,145464,DB06724,10030095,59,7870,19,3900,0.116261822,1.538769909,0.90289209,2.737277279,0.235531379,DB0672410030095_,1.445911129,0.430983337,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,145470,DB00331,10031127,20,24926,31,20721,0.03400176,0.536337306,0.289636079,0.971743529,0.09340889,DB0033110031127_,2.370768756,-0.622992014,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,metformin,DB00331
,145475,DB00722,10031127,21,25382,56,25976,8.87347325565246e-05,0.383756068,0.22066066,0.644143273,0.000720541,DB0072210031127_,7.235507713,-0.957748169,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,lisinopril,DB00722
,145479,DB01136,10031127,14,9870,52,11063,1.82681401671147e-05,0.301803963,0.154359369,0.553059258,0.0001844,DB0113610031127_,8.59840228,-1.197977603,male,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,carvedilol,DB01136
,145490,DB00331,10043882,41,24905,28,20724,0.468671036,1.218458355,0.735238157,2.046572702,0.63511552,DB0033110043882_,0.453948375,0.197586417,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,metformin,DB00331
,145493,DB00787,10043882,32,16968,34,17214,0.902233732,0.954809106,0.570136454,1.595555326,0.957195726,DB0078710043882_,0.043747388,-0.046243848,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,acyclovir,DB00787
,145498,DB06643,10043882,56,52365,11,7504,0.353193982,0.729542878,0.377951548,1.545067074,0.522966642,DB0664310043882_,0.6482376,-0.315337135,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,denosumab,DB06643
,145503,DB00169,10052897,45,38646,16,18159,0.410027592,1.321584266,0.732501426,2.505353851,0.579408379,DB0016910052897_,0.545747732,0.278831218,NA,10052897,Nerve injury,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,145521,DB01234,10052897,28,31597,32,32856,0.796448455,0.909882202,0.527707639,1.56034657,0.889807667,DB0123410052897_,0.116749944,-0.094440136,NA,10052897,Nerve injury,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,145568,DB06643,10043607,60,52361,19,7496,0.005460037,0.452091859,0.265896898,0.802666261,0.021944505,DB0664310043607_,3.819238518,-0.793869893,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,denosumab,DB06643
,145614,DB00635,10026865,49,33004,28,23766,0.356557958,1.260159789,0.776239961,2.083102464,0.526242168,DB0063510026865_,0.641993776,0.23123853,NA,10026865,Mass,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,145616,DB00230,10002948,56,19618,18,8633,0.311626851,1.369100497,0.792314045,2.476034895,0.479038006,DB0023010002948_,0.73597534,0.314153953,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,145617,DB00476,10002948,45,17212,13,6164,0.553459068,1.23963324,0.656637006,2.506439894,0.707011279,DB0047610002948_,0.346708661,0.214815562,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,145623,DB00273,10047513,103,8378,22,2171,0.503682587,1.213181404,0.757878334,2.024745598,0.664806889,DB0027310047513_,0.408258673,0.193246168,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,topiramate,DB00273
,145627,DB00321,10015150,39,7408,11,2839,0.430395332,1.358668487,0.681264669,2.945865809,0.598843525,DB0032110015150_,0.512754943,0.306505166,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,amitriptyline,DB00321
,145628,DB00321,10023232,45,7402,15,2835,0.772377585,1.148994856,0.627438326,2.22268329,0.875404559,DB0032110023232_,0.133069146,0.138887522,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,amitriptyline,DB00321
,145640,DB06605,10007515,65,14008,79,12954,0.112084017,0.760887178,0.538918801,1.071051763,0.229191027,DB0660510007515_,1.473199444,-0.273270188,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,apixaban,DB06605
,145641,DB06605,10033425,281,13792,191,12842,0.000950055,1.369847057,1.133945601,1.657636662,0.00528009,DB0660510033425_,5.243812143,0.314699096,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,145644,DB01005,10012735,64,1031,42,825,0.365938027,1.219220515,0.803954115,1.865503334,0.535503973,DB0100510012735_,0.624546971,0.198211733,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,hydroxyurea,DB01005
,145646,DB01068,10023232,90,13673,22,6818,0.001747034,2.039857369,1.26722133,3.418763545,0.00869547,DB0106810023232_,4.744953075,0.712879888,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,145660,DB01224,10001760,52,8056,16,5901,0.001874852,2.380458625,1.336227034,4.471359638,0.009231148,DB0122410001760_,4.685171873,0.867293169,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,quetiapine,DB01224
,145661,DB01224,10020642,83,8025,45,5872,0.126089554,1.349575493,0.926343451,1.988629339,0.250246446,DB0122410020642_,1.385309062,0.299790093,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,quetiapine,DB01224
,145663,DB00231,10011906,159,3137,128,2011,0.062822567,0.796358231,0.622611147,1.020135983,0.148677907,DB0023110011906_,1.905973013,-0.227706156,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,145664,DB00268,10011906,105,2870,93,1452,0.000160857,0.571257492,0.424805647,0.769214023,0.001197771,DB0026810011906_,6.727293309,-0.559915222,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,145667,DB00158,10011781,75,16740,9,8095,5.79765578631329e-06,4.029160215,2.011895474,9.159380452,6.72638937572968e-05,DB0015810011781_,9.606886962,1.393557971,female,10011781,Cystitis,10021881,Infections and infestations,Infec,folic acid,DB00158
,145668,DB00316,10011781,263,65211,63,36890,4.30384762161581e-11,2.361560658,1.787207302,3.161502185,1.49539503944708e-09,DB0031610011781_,20.32087542,0.859322696,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,145672,DB01075,10011781,111,19837,11,11086,1.4602742145067e-11,5.639895995,3.031092999,11.62898494,5.41754519806756e-10,DB0107510011781_,21.33620813,1.729865625,female,10011781,Cystitis,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,145680,DB00635,10023424,80,32973,33,23761,0.007258182,1.74693494,1.15063204,2.707071048,0.02754368,DB0063510023424_,3.591982162,0.55786279,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,145686,DB00222,10037153,40,3166,24,3104,0.059889153,1.633894821,0.958616943,2.840761684,0.143283701,DB0022210037153_,1.942928694,0.490966626,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,glimepiride,DB00222
,145687,DB00999,10037153,356,21074,165,12074,0.027484329,1.236176484,1.02347043,1.498010338,0.079074604,DB0099910037153_,2.537363523,0.212023135,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,145689,DB00451,10037162,220,47051,37,15382,8.08161741844235e-05,1.943735989,1.366732088,2.835265705,0.000665076,DB0045110037162_,7.315609052,0.664611889,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,145690,DB00999,10037162,124,21306,37,12202,0.000378861,1.919291882,1.319000208,2.853123622,0.002453098,DB0099910037162_,6.010403746,0.651956307,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,145697,DB00264,10038683,49,29558,39,24853,0.831021143,1.056429332,0.679339066,1.652893907,0.911622667,DB0026410038683_,0.092529116,0.054894667,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,145701,DB00863,10049848,70,10603,24,5816,0.051076399,1.599819133,0.99239689,2.663111772,0.127038526,DB0086310049848_,2.063264886,0.469890581,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,145710,DB00863,10056819,48,10625,8,5832,0.000646705,3.293172713,1.54292359,8.066454552,0.003835001,DB0086310056819_,5.563585624,1.191851451,female,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,145714,DB00203,10013781,80,13798,31,8907,0.014752746,1.665842579,1.086738481,2.612376472,0.048672767,DB0020310013781_,3.022635596,0.510331049,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,145716,DB09037,10003988,38,2488,34,2801,0.34399653,1.25819263,0.768500721,2.067424202,0.513280471,DB0903710003988_,0.666932856,0.22967627,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pembrolizumab,DB09037
,145717,DB09037,10016256,170,2356,205,2630,0.485949898,0.925754643,0.745089385,1.1490177,0.649960453,DB0903710016256_,0.430843759,-0.077146043,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pembrolizumab,DB09037
,145719,DB09037,10061428,44,2482,68,2767,0.103857203,0.721403698,0.480203183,1.074069122,0.216795314,DB0903710061428_,1.528801624,-0.326556384,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,pembrolizumab,DB09037
,145737,DB00060,10005186,41,9467,11,2454,0.864665069,0.96616941,0.486811671,2.08748784,0.937999229,DB0006010005186_,0.064006152,-0.034416088,NA,10005186,Blindness unilateral,10015919,Eye disorders,Eye,interferon beta-1a,DB00060
,145749,DB01068,10001488,64,13699,66,6774,3.41862416572937e-05,0.479511294,0.334158684,0.68772964,0.000318146,DB0106810001488_,8.053000271,-0.734987831,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,145760,DB00563,10038428,60,46586,16,15332,0.508153981,1.234158458,0.701547933,2.296352094,0.66876728,DB0056310038428_,0.402319143,0.210389327,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,methotrexate,DB00563
,145777,DB06700,10013968,51,2174,14,604,1,1.012088382,0.547246637,1.993913522,1,DB0670010013968_,0,0.012015901,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,desvenlafaxine,DB06700
,145780,DB00231,10016322,57,3239,23,2116,0.050745541,1.61888151,0.978236583,2.762165542,0.126389022,DB0023110016322_,2.068390652,0.481735485,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,145784,DB00829,10039897,30,8022,44,4410,4.15225457235941e-05,0.374851661,0.227167009,0.610838255,0.000376741,DB0082910039897_,7.883951292,-0.981224902,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,145790,DB08895,10024774,115,27999,25,6621,0.829349544,1.087748979,0.70041535,1.751806625,0.910396858,DB0889510024774_,0.093874667,0.084110404,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,145800,DB00904,10024378,73,22996,54,14402,0.362026463,0.846650821,0.58704174,1.227688823,0.531735413,DB0090410024378_,0.631609256,-0.166466923,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,ondansetron,DB00904
,145809,DB00218,10011906,36,1406,41,909,0.017418199,0.567830124,0.349671104,0.918452141,0.05544839,DB0021810011906_,2.892302597,-0.565932983,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,moxifloxacin,DB00218
,145810,DB00535,10011906,39,1165,42,604,0.001762332,0.481616414,0.29978948,0.772209991,0.008759176,DB0053510011906_,4.737653447,-0.730607302,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cefdinir,DB00535
,145827,DB06403,10047513,125,21346,30,6631,0.219048928,1.294328029,0.862289532,1.999958242,0.37236547,DB0640310047513_,0.987879461,0.257991664,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ambrisentan,DB06403
,145830,DB00028,10016173,163,13295,48,5567,0.033284484,1.421960739,1.023173445,2.008214317,0.091875311,DB0002810016173_,2.387322935,0.352036721,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,human immunoglobulin g,DB00028
,145832,DB00668,10016173,158,9933,49,4254,0.055565802,1.380973697,0.994257943,1.947712127,0.135279684,DB0066810016173_,2.000410914,0.322788828,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,epinephrine,DB00668
,145876,DB00727,10037087,82,3761,35,4138,1.39658078411132e-06,2.577419974,1.71056328,3.956275933,1.93409514806987e-05,DB0072710037087_,10.85328587,0.946788889,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,nitroglycerin,DB00727
,145877,DB00950,10037087,133,4585,34,2022,0.00372533,1.724977171,1.17118656,2.603635438,0.016100015,DB0095010037087_,4.128935076,0.545213816,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,fexofenadine,DB00950
,145880,DB13867,10037087,96,4454,32,2522,0.00908597,1.698580552,1.124058544,2.627801389,0.032975452,DB1386710037087_,3.411991879,0.529792933,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone,DB13867
,145881,DB00043,10048959,75,6338,21,2279,0.352585284,1.284152946,0.780699245,2.199474651,0.52235961,DB0004310048959_,0.64939902,0.250099315,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,145883,DB13867,10048959,73,4477,25,2529,0.033571504,1.649362783,1.031548286,2.718927858,0.092507284,DB1386710048959_,2.380467888,0.500389021,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,145886,DB06769,10053762,31,636,34,1022,0.152953929,1.464751067,0.861270271,2.48302193,0.288138324,DB0676910053762_,1.244314624,0.381685308,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,bendamustine,DB06769
,145890,DB00874,10033371,111,3224,42,1934,0.010867812,1.585256604,1.096693697,2.328933857,0.038047474,DB0087410033371_,3.268920588,0.46074629,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,145901,DB00065,10002855,82,9382,20,4937,0.001554975,2.15740292,1.308846015,3.719193394,0.007919496,DB0006510002855_,4.838427716,0.768905146,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,infliximab,DB00065
,145922,DB06643,10047899,194,52227,28,7487,0.919367444,0.993244993,0.66549775,1.534999656,0.964366314,DB0664310047899_,0.036284063,-0.006777925,NA,10047899,Weight increased,10022891,Investigations,Inv,denosumab,DB06643
,145935,DB00722,10063829,41,25362,42,25990,1,1.000376948,0.63418938,1.576893348,1,DB0072210063829_,0,0.000376877,NA,10063829,Device malfunction,10077536,Product issues,Prod,lisinopril,DB00722
,145938,DB08932,10051055,59,19384,18,6579,0.793312551,1.112484109,0.646520595,2.005698633,0.887941952,DB0893210051055_,0.118848907,0.106595451,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,macitentan,DB08932
,145943,DB00158,10048334,95,16720,25,8079,0.006007785,1.836096323,1.170486565,2.980560929,0.023691854,DB0015810048334_,3.742624003,0.607641754,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,145944,DB00338,10048334,111,33563,44,22228,0.003888502,1.670726963,1.167854708,2.427292453,0.016670897,DB0033810048334_,4.09409075,0.513258839,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,145945,DB00758,10048334,47,8253,33,10041,0.017611057,1.732725908,1.085736963,2.794501156,0.055944444,DB0075810048334_,2.883396148,0.549695838,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,clopidogrel,DB00758
,145948,DB00169,10049438,77,38614,51,18124,0.058074134,0.708635164,0.490834827,1.030718025,0.139832238,DB0016910049438_,1.967311878,-0.344414463,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,145949,DB00158,10062355,105,16710,52,8052,0.864621206,0.972977995,0.690675795,1.385544912,0.937971003,DB0015810062355_,0.064036244,-0.027393813,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,145950,DB00338,10062355,204,33470,145,22127,0.510777333,0.930100399,0.747546136,1.159646514,0.671136238,DB0033810062355_,0.398783126,-0.072462743,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,145951,DB00758,10062355,60,8240,48,10026,0.032745595,1.520880713,1.021990448,2.273945304,0.09071648,DB0075810062355_,2.400016245,0.419289584,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,145959,DB00190,10005750,54,3243,92,4582,0.308990883,0.829329221,0.579533312,1.176850632,0.476339568,DB0019010005750_,0.7416243,-0.187138072,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,carbidopa,DB00190
,145979,DB01202,10028372,61,6653,44,5674,0.432168377,1.182341434,0.787963105,1.786945601,0.600631189,DB0120210028372_,0.509774196,0.167496738,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,levetiracetam,DB01202
,145980,DB00678,10051398,35,15564,57,10667,4.4314490187532e-05,0.420848493,0.26791869,0.652777757,0.000398701,DB0067810051398_,7.827297591,-0.865482385,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,losartan,DB00678
,145981,DB00758,10051398,7,8293,44,10030,2.97287066099832e-06,0.192428318,0.073075056,0.430937152,3.75918403426735e-05,DB0075810051398_,10.18872354,-1.648031571,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,clopidogrel,DB00758
,145982,DB01050,10051398,41,18067,51,9320,3.43541218190482e-05,0.414720099,0.267808217,0.638648499,0.000319476,DB0105010051398_,8.048829315,-0.880151447,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ibuprofen,DB01050
,145985,DB00814,10002855,168,8119,44,3371,0.005961184,1.585257157,1.128460889,2.268357953,0.023544661,DB0081410002855_,3.748856189,0.460746638,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,meloxicam,DB00814
,145988,DB00814,10003658,37,8250,40,3375,3.91449293308625e-05,0.378444315,0.234895661,0.608307657,0.000358198,DB0081410003658_,7.934423959,-0.971686338,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,meloxicam,DB00814
,145998,DB01050,10038153,43,18065,17,9354,0.413791482,1.309741796,0.731094006,2.450795896,0.583128302,DB0105010038153_,0.539348045,0.269830016,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,ibuprofen,DB01050
,146030,DB00864,10037032,24,6845,46,8346,0.072113695,0.636167918,0.371024508,1.065293542,0.164975847,DB0086410037032_,1.801956198,-0.452292728,NA,10037032,Proteinuria,10038359,Renal and urinary disorders,Renal,tacrolimus,DB00864
,146040,DB01590,10000087,68,4670,37,2830,0.685216821,1.113725493,0.733435387,1.714936464,0.809887557,DB0159010000087_,0.210859859,0.107710695,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,everolimus,DB01590
,146048,DB08908,10048709,41,10632,16,3263,0.43377604,0.786455199,0.431188378,1.503397488,0.602298049,DB0890810048709_,0.507002858,-0.240219521,NA,10048709,Urosepsis,10021881,Infections and infestations,Infec,dimethyl fumarate,DB08908
,146049,DB01097,10021789,153,6112,34,1469,0.778562558,1.081530619,0.738176947,1.62534319,0.879305512,DB0109710021789_,0.128622874,0.078377277,NA,10021789,Infection,10021881,Infections and infestations,Infec,leflunomide,DB01097
,146050,DB00924,10038435,77,10085,44,4207,0.10877117,0.730030407,0.496745095,1.084693799,0.224186482,DB0092410038435_,1.495277064,-0.314669093,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,cyclobenzaprine,DB00924
,146052,DB00924,10058080,32,10130,18,4233,0.350960044,0.742881938,0.404097884,1.407321308,0.520670792,DB0092410058080_,0.652637314,-0.297218146,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,cyclobenzaprine,DB00924
,146059,DB00641,10003285,55,14069,39,12436,0.302468274,1.246555102,0.811501926,1.931275032,0.468827608,DB0064110003285_,0.757520151,0.220383829,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,146060,DB00787,10003285,96,16904,91,17157,0.660416217,1.070766534,0.794685484,1.443576053,0.792704535,DB0078710003285_,0.232304718,0.068374779,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,146068,DB00635,10038683,84,32969,45,23749,0.128471183,1.344633089,0.924993961,1.977486368,0.25346131,DB0063510038683_,1.372544091,0.29612118,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,146069,DB00695,10038683,79,27970,33,20495,0.007060456,1.754131308,1.154237511,2.720497325,0.026969175,DB0069510038683_,3.613060735,0.561973753,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,146075,DB00924,10028391,64,10098,25,4226,0.816645948,1.071350939,0.664194307,1.778251334,0.901856553,DB0092410028391_,0.103299804,0.068920412,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,146081,DB00005,10010007,60,128022,19,42400,1,1.04590329,0.615457314,1.85606589,1,DB0000510010007_,0,0.044880904,NA,10010007,Colonoscopy,10022891,Investigations,Inv,etanercept,DB00005
,146089,DB00524,10000060,45,1532,19,1325,0.007769545,2.047878932,1.167053103,3.726927816,0.029093594,DB0052410000060_,3.537237263,0.71680459,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,metolazone,DB00524
,146095,DB00524,10010264,94,1483,47,1297,0.002329756,1.748827212,1.209059239,2.558769076,0.011017926,DB0052410010264_,4.508231728,0.558945399,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,146098,DB00571,10016256,245,4878,123,2486,0.910193339,1.015125164,0.809551186,1.278107809,0.959573168,DB0057110016256_,0.04126671,0.015011919,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,146131,DB00641,10011781,62,14062,14,12461,3.53983976367212e-07,3.924060929,2.171139839,7.594908003,5.66827220153041e-06,DB0064110011781_,12.08062621,1.367127069,female,10011781,Cystitis,10021881,Infections and infestations,Infec,simvastatin,DB00641
,146138,DB00316,10061819,50,65424,21,36932,0.268777602,1.344049337,0.792520369,2.356384994,0.431228669,DB0031610061819_,0.841116776,0.29568695,NA,10061819,Disease recurrence,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,146139,DB00451,10061819,46,47225,9,15410,0.208809328,1.667737061,0.806348917,3.876442203,0.359869729,DB0045110061819_,1.022013176,0.511467654,NA,10061819,Disease recurrence,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,146142,DB08895,10061819,84,28030,17,6629,0.614300459,1.168565709,0.68761858,2.101483891,0.755840897,DB0889510061819_,0.279924379,0.155777107,NA,10061819,Disease recurrence,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,146172,DB00650,10009887,24,2107,32,1982,0.226140835,0.705568794,0.396136268,1.241004072,0.381035623,DB0065010009887_,0.96486241,-0.348751001,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,leucovorin,DB00650
,146174,DB00413,10010305,38,2161,47,1160,0.000196778,0.434108575,0.273667484,0.684620246,0.001421552,DB0041310010305_,6.556006381,-0.834460603,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,pramipexole,DB00413
,146177,DB00472,10020642,92,10667,36,4276,1,1.024438756,0.688578838,1.553440525,1,DB0047210020642_,0,0.024144907,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,fluoxetine,DB00472
,146185,DB00678,10024264,61,15538,44,10680,0.842460279,0.95293952,0.635625743,1.438914444,0.919801687,DB0067810024264_,0.08359719,-0.048203841,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,losartan,DB00678
,146191,DB00338,10057668,92,33582,65,22207,0.683906366,0.93596269,0.673615449,1.306988025,0.808956803,DB0033810057668_,0.212009759,-0.066179664,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,146192,DB00678,10057668,36,15563,34,10690,0.182834567,0.72731195,0.442045168,1.198939137,0.327460248,DB0067810057668_,1.116388612,-0.318399802,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,losartan,DB00678
,146206,DB00668,10022061,84,10007,20,4283,0.017629746,1.797537414,1.092026313,3.095888241,0.055989595,DB0066810022061_,2.882589415,0.586417625,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,146212,DB00668,10053425,63,10028,9,4294,0.000704761,2.99707294,1.480937399,6.862447327,0.004116585,DB0066810053425_,5.492731463,1.097636126,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,146219,DB00190,10008190,32,3265,38,4636,0.466714917,1.195678857,0.721506946,1.970047078,0.633373673,DB0019010008190_,0.45669471,0.178714105,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,146220,DB00190,10012239,77,3220,173,4501,0.000526922,0.622189915,0.467509412,0.82178012,0.003222465,DB0019010012239_,5.737608539,-0.474509903,NA,10012239,Delusion,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,146226,DB00437,10003445,16,6905,42,11504,0.135483149,0.634696502,0.332843176,1.153880218,0.263410228,DB0043710003445_,1.334042662,-0.454608345,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,146251,DB01115,10000059,53,3547,22,2246,0.120154756,1.52535864,0.90901909,2.641604348,0.24157783,DB0111510000059_,1.42056358,0.422229556,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,nifedipine,DB01115
,146253,DB00682,10019016,27,19432,46,16318,0.003164779,0.492911328,0.294519265,0.810156882,0.014137697,DB0068210019016_,4.258910481,-0.707425983,NA,10019016,Haemorrhagic stroke,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,146257,DB00005,10038743,40,128042,12,42407,0.873126624,1.103985273,0.567757712,2.311909235,0.944702629,DB0000510038743_,0.056885079,0.098926608,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,146262,DB09037,10012735,110,2416,123,2712,1,1.003876032,0.76439719,1.317085284,1,DB0903710012735_,0,0.00386854,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pembrolizumab,DB09037
,146268,DB09037,10028813,145,2381,89,2746,3.41269796650496e-06,1.878724092,1.424454186,2.489071093,4.22627873025126e-05,DB0903710028813_,10.07160359,0.630592872,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pembrolizumab,DB09037
,146270,DB09037,10047700,82,2444,45,2790,6.83396830051561e-05,2.079933376,1.422477675,3.075368993,0.000574911,DB0903710047700_,7.461295786,0.732335862,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pembrolizumab,DB09037
,146275,DB00881,10028813,42,670,20,570,0.03665958,1.785798607,1.011765764,3.250272462,0.098901473,DB0088110028813_,2.31363115,0.579865714,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,quinapril,DB00881
,146279,DB00051,10061224,41,25690,11,11409,0.174891863,1.655271857,0.835199922,3.571988338,0.317321227,DB0005110061224_,1.147840684,0.503965259,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,146297,DB00108,10061284,54,10140,20,3275,0.588723347,0.872070035,0.512616031,1.540447987,0.735582809,DB0010810061284_,0.307092157,-0.136885543,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,natalizumab,DB00108
,146338,DB01234,10069327,38,31587,21,32867,0.01902222,1.882819652,1.077039553,3.377703305,0.059417595,DB0123410069327_,2.823164878,0.632770468,NA,10069327,Product quality issue,10077536,Product issues,Prod,dexamethasone,DB01234
,146345,DB00695,10041660,29,28020,37,20491,0.024934463,0.573199585,0.339879859,0.958115265,0.073335835,DB0069510041660_,2.61270591,-0.556521307,NA,10041660,Splenomegaly,10005329,Blood and lymphatic system disorders,Blood,furosemide,DB00695
,146356,DB00230,10061422,45,19629,22,8629,0.69121854,0.899199974,0.528425401,1.573384564,0.813814047,DB0023010061422_,0.206023382,-0.106249829,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,146362,DB00555,10005750,33,7014,25,3461,0.12306073,0.651355995,0.375030452,1.144511172,0.24581285,DB0055510005750_,1.403184806,-0.428698943,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,lamotrigine,DB00555
,146364,DB01136,10006784,39,9845,36,11079,0.418433632,1.219106582,0.754278678,1.975331551,0.587449754,DB0113610006784_,0.531964561,0.198118281,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,146368,DB00722,10013082,63,25340,41,25991,0.02386523,1.576037207,1.046514512,2.396518264,0.07091714,DB0072210013082_,2.646243122,0.4549136,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,146382,DB01076,10014020,55,25692,8,25575,9.66324056675272e-10,6.843399076,3.240323848,16.63626898,2.6963723810732e-08,DB0107610014020_,17.42877344,1.923284549,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,atorvastatin,DB01076
,146419,DB00215,10001488,24,11079,33,5243,8.47637114876774e-05,0.344197401,0.1944337,0.600972676,0.000693114,DB0021510001488_,7.274316428,-1.066539947,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,146465,DB00213,10020100,59,18836,45,13376,0.765164078,0.931061246,0.620633069,1.405238567,0.870437886,DB0021310020100_,0.138758877,-0.071430219,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,146468,DB01104,10020100,46,15417,16,7270,0.341027368,1.35575127,0.752732927,2.567252619,0.510254981,DB0110410020100_,0.672844716,0.304355744,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,146471,DB00695,10000880,25,28024,32,20496,0.043290899,0.571404438,0.32450741,0.995459159,0.112241199,DB0069510000880_,2.18710516,-0.559658023,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,furosemide,DB00695
,146490,DB01377,10037423,44,3752,13,2657,0.004262907,2.396525645,1.264717864,4.859851037,0.017992858,DB0137710037423_,4.017780377,0.87402004,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium oxide,DB01377
,146493,DB00836,10061818,86,5449,67,4008,0.741963186,0.94415899,0.676154511,1.323102369,0.852096878,DB0083610061818_,0.160055052,-0.057460705,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,146494,DB01377,10061818,62,3734,34,2636,0.252219962,1.287262385,0.831341602,2.023674046,0.412327126,DB0137710061818_,0.885938249,0.252517781,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,146508,DB00051,10037884,114,25617,46,11374,0.607750726,1.100347823,0.774299932,1.586470282,0.750621551,DB0005110037884_,0.286853681,0.095626333,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,146518,DB00046,10005750,42,5417,32,4660,0.641041436,1.129057683,0.694665943,1.851235129,0.777921244,DB0004610005750_,0.251129989,0.121383376,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,insulin lispro,DB00046
,146519,DB00047,10005750,66,9219,32,8486,0.003081124,1.898437822,1.225338787,2.99625946,0.013829805,DB0004710005750_,4.280929223,0.641031349,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,insulin glargine,DB00047
,146520,DB00758,10005750,87,8213,65,10009,0.003117558,1.631086828,1.1676285,2.288341222,0.013964359,DB0075810005750_,4.271246982,0.489246559,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,clopidogrel,DB00758
,146536,DB00863,10033318,54,10619,20,5820,0.144621442,1.47976721,0.870404496,2.612635005,0.276495877,DB0086310033318_,1.285559371,0.391884785,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,ranitidine,DB00863
,146538,DB00863,10043071,63,10610,52,5788,0.031000594,0.660912097,0.449857781,0.974745378,0.086923057,DB0086310043071_,2.442731957,-0.414134432,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,ranitidine,DB00863
,146539,DB01050,10043071,131,17977,52,9319,0.117403823,1.305950045,0.939270067,1.839000519,0.237290234,DB0105010043071_,1.438471271,0.26693078,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,ibuprofen,DB01050
,146558,DB00153,10047571,72,7351,16,3423,0.005547574,2.09530714,1.204657441,3.865985032,0.022230047,DB0015310047571_,3.806310434,0.739700149,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,ergocalciferol,DB00153
,146568,DB00688,10021789,81,6409,53,5325,0.190950666,1.269782678,0.88537177,1.834382078,0.337761659,DB0068810021789_,1.085414784,0.238845766,NA,10021789,Infection,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,146585,DB00338,10061148,54,33620,39,22233,0.672986632,0.915652461,0.595173353,1.420251653,0.801533955,DB0033810061148_,0.221227944,-0.088118396,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,146596,DB00684,10061428,38,2754,18,2330,0.043352875,1.785891594,0.991431157,3.333798873,0.112374174,DB0068410061428_,2.185921132,0.579917783,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,tobramycin,DB00684
,146597,DB00698,10061428,44,3104,13,416,0.020857558,0.453740418,0.237587095,0.92624317,0.06388083,DB0069810061428_,2.750735955,-0.79023001,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,nitrofurantoin,DB00698
,146598,DB00484,10011906,73,2434,65,1715,0.188090094,0.791372846,0.555299784,1.129786408,0.334152149,DB0048410011906_,1.096158852,-0.233986062,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,brimonidine,DB00484
,146609,DB00115,10013710,67,18358,35,10437,0.757179039,1.08832768,0.712235205,1.689247747,0.864234272,DB0011510013710_,0.145911399,0.084642279,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,146622,DB00169,10029216,142,38549,33,18142,0.000124114,2.025077637,1.377840165,3.055861776,0.000959513,DB0016910029216_,6.949084306,0.705608039,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,146638,DB00641,10013946,90,14034,47,12428,0.003390483,1.695721509,1.177812409,2.469276071,0.014930281,DB0064110013946_,4.204363818,0.528108319,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,146646,DB00190,10013950,70,3227,89,4585,0.515581262,1.117484736,0.802435164,1.551066015,0.67535455,DB0019010013950_,0.392517467,0.111080388,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,carbidopa,DB00190
,146663,DB01175,10016825,70,10654,27,4865,0.510754659,1.183845877,0.748438821,1.922808602,0.671136238,DB0117510016825_,0.398783126,0.168768357,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,escitalopram,DB01175
,146665,DB01175,10042772,84,10640,53,4839,0.064644329,0.720805122,0.504189994,1.038523205,0.151827385,DB0117510042772_,1.885011029,-0.327386467,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,146667,DB01175,10060800,55,10669,10,4882,0.004587755,2.516607745,1.269134577,5.541849859,0.019065477,DB0117510060800_,3.959876063,0.922911862,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,escitalopram,DB01175
,146673,DB00213,10001551,82,18813,90,13331,0.005076544,0.645641944,0.472337061,0.881444879,0.020708768,DB0021310001551_,3.877198084,-0.437510195,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,pantoprazole,DB00213
,146677,DB06724,10001551,32,7897,20,3899,0.460236796,0.790009414,0.437507916,1.459491105,0.627666184,DB0672410001551_,0.465746808,-0.235710417,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,calcium carbonate,DB06724
,146682,DB00213,10003481,92,18803,81,13340,0.164118597,0.80581932,0.590730324,1.100991295,0.302896878,DB0021310003481_,1.194362869,-0.21589573,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,pantoprazole,DB00213
,146686,DB06724,10003481,37,7892,20,3899,0.778229159,0.913992029,0.516122877,1.664331668,0.879072925,DB0672410003481_,0.128887421,-0.089933429,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,calcium carbonate,DB06724
,146713,DB00695,10005364,113,27936,74,20454,0.504570211,1.118081039,0.826197674,1.520716557,0.665548334,DB0069510005364_,0.407144016,0.111613858,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,furosemide,DB00695
,146739,DB00559,10010305,67,9592,19,3287,0.535617685,1.208379847,0.715913648,2.133792068,0.692151661,DB0055910010305_,0.367950184,0.189280493,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,bosentan,DB00559
,146753,DB09153,10014625,32,7767,35,5664,0.107089747,0.666765798,0.399138679,1.110315947,0.221755544,DB0915310014625_,1.506179659,-0.405316423,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,146758,DB14513,10021097,96,7081,63,3501,0.089584975,0.753454923,0.54115995,1.055229,0.194550425,DB1451310021097_,1.637063894,-0.283086086,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,magnesium,DB14513
,146772,DB14513,10030124,89,7088,50,3514,0.470007885,0.88248219,0.615698851,1.277165769,0.636271072,DB1451310030124_,0.452130593,-0.125016672,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,146774,DB00476,10038695,90,17167,32,6145,1,1.006746787,0.665001679,1.559700573,1,DB0047610038695_,0,0.006724129,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,146776,DB06724,10038695,68,7861,52,3867,0.019073164,0.643293759,0.440788098,0.943631774,0.05953074,DB0672410038695_,2.821262465,-0.441153803,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,146778,DB14513,10038695,44,7133,24,3540,0.700026184,0.909866497,0.540347509,1.56705787,0.819771814,DB1451310038695_,0.198729253,-0.094457397,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium,DB14513
,146782,DB14513,10040047,64,7113,48,3516,0.033803026,0.659085852,0.445252485,0.981419928,0.092979546,DB1451310040047_,2.375375747,-0.416901476,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,magnesium,DB14513
,146783,DB00646,10041349,34,3419,16,1984,0.557007675,1.233100864,0.660316113,2.398803586,0.710217516,DB0064610041349_,0.342183995,0.209532024,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,nystatin,DB00646
,146784,DB01109,10041349,38,4374,27,4243,0.262306084,1.365202875,0.81031416,2.329656896,0.424068359,DB0110910041349_,0.857860612,0.311303044,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,heparin,DB01109
,146787,DB14500,10041349,66,7743,41,4032,0.413109986,0.838269211,0.558122184,1.272228979,0.582542703,DB1450010041349_,0.540352787,-0.176415976,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,potassium,DB14500
,146837,DB00480,10052137,48,67380,34,67628,0.123135559,1.41695089,0.89424744,2.267821396,0.245868899,DB0048010052137_,1.402956818,0.348507302,NA,10052137,Ear discomfort,10013993,Ear and labyrinth disorders,Ear,lenalidomide,DB00480
,146853,DB01101,10040047,36,7553,35,3873,0.008037115,0.527438667,0.321339505,0.866595034,0.029895362,DB0110110040047_,3.51005194,-0.639722692,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,capecitabine,DB01101
,146862,DB00188,10020751,63,7823,33,8795,0.000300787,2.146211536,1.385370513,3.38028662,0.002022301,DB0018810020751_,6.203519176,0.763704212,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,bortezomib,DB00188
,146864,DB00950,10020751,93,4625,28,2028,0.089788166,1.456349524,0.942122546,2.316402828,0.194886597,DB0095010020751_,1.635337446,0.375932979,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,fexofenadine,DB00950
,146871,DB00588,10028164,46,16478,11,8457,0.023986896,2.14617587,1.094323645,4.597598163,0.071210251,DB0058810028164_,2.642118499,0.763687593,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,fluticasone propionate,DB00588
,146873,DB00996,10028164,44,38909,13,22412,0.038021289,1.949553282,1.031047656,3.946643466,0.101662131,DB0099610028164_,2.286100402,0.66760026,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,gabapentin,DB00996
,146879,DB01076,10003662,32,25715,60,25523,0.003346089,0.529360888,0.333373789,0.826500958,0.01477191,DB0107610003662_,4.215027904,-0.636084872,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,146907,DB00863,10022000,131,10542,67,5773,0.708607492,1.070719476,0.79023982,1.462231201,0.826067099,DB0086310022000_,0.191079275,0.06833083,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ranitidine,DB00863
,146908,DB01062,10022000,50,4436,13,1732,0.207159669,1.501669807,0.801142648,3.021185378,0.357839551,DB0106210022000_,1.027670574,0.406577693,NA,10022000,Influenza,10021881,Infections and infestations,Infec,oxybutynin,DB01062
,146910,DB09153,10022000,119,7680,93,5606,0.624484012,0.934024779,0.704487114,1.241472587,0.764285619,DB0915310022000_,0.268813712,-0.068252311,NA,10022000,Influenza,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,146926,DB00423,10012735,105,2362,38,1002,0.454990908,1.172115485,0.795143604,1.759833515,0.622563041,DB0042310012735_,0.473910385,0.158810223,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,methocarbamol,DB00423
,146927,DB08895,10028735,282,27832,49,6597,0.048917335,1.364111395,1.002973803,1.889746469,0.122954067,DB0889510028735_,2.095944433,0.310503224,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,146981,DB00188,10073133,33,7853,47,8781,0.313271221,0.785111507,0.486766248,1.253042132,0.480841948,DB0018810073133_,0.732216654,-0.241929524,NA,10073133,Plasma cell myeloma recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,bortezomib,DB00188
,147007,DB00727,10047302,11,3832,52,4121,6.75642138419882e-07,0.227535781,0.106868476,0.442232284,1.0127889140785e-05,DB0072710047302_,11.50021764,-1.480447773,male,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,nitroglycerin,DB00727
,147024,DB01175,10028836,45,10679,19,4873,0.892713641,1.080742094,0.618695116,1.95873594,0.9552998,DB0117510028836_,0.045730061,0.077647929,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,147040,DB01065,10019211,238,4093,76,2975,1.13202200238215e-10,2.275927846,1.742782917,3.000085903,3.65992599417157e-09,DB0106510019211_,19.42582291,0.822387813,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,melatonin,DB01065
,147042,DB01065,10028411,52,4279,19,3032,0.014848347,1.939092314,1.124596512,3.480537769,0.048911437,DB0106510028411_,3.017744032,0.662219984,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,melatonin,DB01065
,147054,DB01067,10037087,101,4260,75,4748,0.009388515,1.500853255,1.098886179,2.057490846,0.033849134,DB0106710037087_,3.385841856,0.406033783,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,glipizide,DB01067
,147060,DB06724,10000060,78,7851,30,3889,0.259542562,1.287933217,0.833741013,2.036799626,0.42068734,DB0672410000060_,0.865865381,0.253038776,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,147080,DB00451,10005287,39,47232,11,15408,0.744991709,1.15659156,0.580726734,2.504462558,0.854423591,DB0045110005287_,0.1573282,0.145477369,NA,10005287,Blood albumin decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,147092,DB01233,10005483,26,3395,34,1692,0.000270299,0.381190787,0.21889838,0.656742135,0.001852624,DB0123310005483_,6.291152088,-0.964455276,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,metoclopramide,DB01233
,147093,DB06724,10005483,45,7884,40,3879,0.007562016,0.553512146,0.352802276,0.87128008,0.028476734,DB0672410005483_,3.558667879,-0.591471584,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,calcium carbonate,DB06724
,147120,DB00451,10005802,102,47169,24,15395,0.177671152,1.387086078,0.881939027,2.264479306,0.320901961,DB0045110005802_,1.136619621,0.3272052,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,147147,DB06724,10020919,40,7889,28,3891,0.156897647,0.70459816,0.423296943,1.187878893,0.293326507,DB0672410020919_,1.226468932,-0.350127625,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,calcium carbonate,DB06724
,147148,DB09153,10020919,41,7758,37,5662,0.359581312,0.808745676,0.505082612,1.298923381,0.529276386,DB0915310020919_,0.636244515,-0.212270779,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,sodium chloride,DB09153
,147155,DB00863,10028735,86,10587,18,5822,7.49660111660062e-05,2.627257433,1.565846062,4.645704694,0.000622487,DB0086310028735_,7.381788318,0.965940501,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,147159,DB06724,10028735,58,7871,12,3907,0.004649581,2.399017189,1.272453461,4.913687678,0.019284296,DB0672410028735_,3.94846419,0.875059149,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,147185,DB00863,10039101,83,10590,29,5811,0.037156072,1.570449171,1.016491332,2.490039129,0.099883825,DB0086310039101_,2.30374752,0.451361674,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,147190,DB09153,10039101,33,7766,22,5677,0.7856642,1.096527495,0.619627389,1.976401347,0.883734037,DB0915310039101_,0.123599125,0.092148364,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,147204,DB14512,10064385,90,4754,60,2352,0.080031022,0.74211454,0.527313967,1.050835796,0.178452133,DB1451210064385_,1.723434878,-0.298251682,NA,10064385,Circumstance or information capable of leading to medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,mometasone furoate,DB14512
,147211,DB08932,10010253,58,19385,21,6576,0.795997236,0.936921361,0.559606634,1.626604824,0.889513883,DB0893210010253_,0.117080164,-0.065155926,NA,10010253,Concomitant disease aggravated,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,147212,DB08932,10038687,115,19328,46,6551,0.36321578,0.847378799,0.596281993,1.221744973,0.532748906,DB0893210038687_,0.629705061,-0.16560746,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,147217,DB00928,10016288,109,726,182,1104,0.518403319,0.91074004,0.698546577,1.18348513,0.67766909,DB0092810016288_,0.389096178,-0.093497779,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,azacitidine,DB00928
,147228,DB00695,10005395,50,27999,24,20504,0.099050289,1.525635101,0.919809486,2.596609633,0.209430627,DB0069510005395_,1.563362728,0.422410783,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,furosemide,DB00695
,147231,DB01234,10005395,44,31581,35,32853,0.260630095,1.307767283,0.819674706,2.100804261,0.422098709,DB0123410005395_,0.862516085,0.268321319,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,147288,DB00295,10007554,30,14633,33,9569,0.039580165,0.594516842,0.349982558,1.006228549,0.104817354,DB0029510007554_,2.25553593,-0.520006234,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,morphine,DB00295
,147291,DB00736,10007554,33,10558,21,5532,0.476732358,0.823393355,0.46190273,1.49906735,0.642116835,DB0073610007554_,0.442985006,-0.194321239,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,esomeprazole,DB00736
,147294,DB00046,10011906,174,5285,246,4446,2.36442590966605e-07,0.595068541,0.485161978,0.728621284,3.94596412924267e-06,DB0004610011906_,12.44281724,-0.519078685,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,147317,DB00787,10037423,63,16937,57,17191,0.583420965,1.121834197,0.770964167,1.635453525,0.731448741,DB0078710037423_,0.312728135,0.114965022,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,147318,DB00864,10037423,41,6828,33,8359,0.079032211,1.520943992,0.937109629,2.48584906,0.17674409,DB0086410037423_,1.733052414,0.419331189,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tacrolimus,DB00864
,147321,DB01109,10037423,44,4368,36,4234,0.500822628,1.184703011,0.743646354,1.898354744,0.662312477,DB0110910037423_,0.412017815,0.16949212,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,heparin,DB01109
,147322,DB00211,10038435,29,1407,30,1601,0.792523274,1.099917828,0.633559645,1.906886145,0.887531177,DB0021110038435_,0.119311629,0.095235475,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,midodrine,DB00211
,147331,DB11065,10010264,71,3115,48,2640,0.26464493,1.253562503,0.853621245,1.854748419,0.426610334,DB1106510010264_,0.85188425,0.2259895,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,pancrelipase amylase,DB11065
,147336,DB08882,10013709,30,967,23,970,0.403796676,1.308214317,0.728807103,2.376912539,0.573470695,DB0888210013709_,0.556048442,0.26866309,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,linagliptin,DB08882
,147340,DB01136,10013887,32,9852,29,11086,0.441694201,1.241642493,0.726945768,2.129012864,0.609894929,DB0113610013887_,0.494468584,0.216435094,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,147346,DB00230,10005734,52,19622,19,8632,0.522090171,1.203954313,0.699449289,2.157857591,0.680767224,DB0023010005734_,0.384534847,0.1856114,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,pregabalin,DB00230
,147349,DB00678,10005734,76,15523,47,10677,0.582636134,1.112238607,0.762438672,1.637368826,0.730797423,DB0067810005734_,0.313618981,0.106374747,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,losartan,DB00678
,147350,DB01222,10005734,32,9242,20,5385,0.885619858,0.932271038,0.516494594,1.721711679,0.952411128,DB0122210005734_,0.04875848,-0.070131693,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,budesonide,DB01222
,147363,DB00678,10027599,86,15513,16,10708,7.52345628054124e-08,3.709970544,2.15814805,6.784379565,1.39903819125593e-06,DB0067810027599_,13.47972556,1.311023937,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,losartan,DB00678
,147380,DB00374,10003246,66,17650,15,5709,0.24473221,1.423162858,0.802876663,2.687293107,0.403496522,DB0037410003246_,0.90758741,0.352881759,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,147381,DB08932,10054997,65,19378,13,6584,0.089508741,1.698726523,0.926649921,3.361966126,0.194473241,DB0893210054997_,1.637460705,0.529878866,NA,10054997,Infusion site infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,147383,DB08932,10028334,292,19151,90,6507,0.44156525,1.10237083,0.865961213,1.414682722,0.609795497,DB0893210028334_,0.494631628,0.097463161,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,147390,DB08932,10001760,97,19346,11,6586,0.000132989,3.002039866,1.604253203,6.216283555,0.00101661,DB0893210001760_,6.891281733,1.099292013,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,macitentan,DB08932
,147391,DB08880,10025482,96,3242,13,796,0.04904762,1.812872594,1.004912472,3.546819471,0.123187299,DB0888010025482_,2.094049324,0.594912656,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,teriflunomide,DB08880
,147396,DB00722,10057362,63,25340,67,25965,0.8608492,0.963482306,0.671774745,1.380450366,0.934669801,DB0072210057362_,0.067561966,-0.037201155,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,147402,DB00203,10061822,133,13745,72,8866,0.250426169,1.191479357,0.886682,1.61218938,0.410172722,DB0020310061822_,0.891176935,0.175195693,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,147403,DB00368,10007515,71,589,60,738,0.034329652,1.482255704,1.017826283,2.16449504,0.094068794,DB0036810007515_,2.363728912,0.393565052,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,norepinephrine,DB00368
,147413,DB00158,10017076,130,16685,20,8084,9.6223993763774e-08,3.14918097,1.955880869,5.330028761,1.74551254387909e-06,DB0015810017076_,13.25846232,1.14714241,female,10017076,Fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,147436,DB00169,10037855,84,38607,37,18138,0.845311028,1.066596292,0.716062032,1.616344575,0.922007609,DB0016910037855_,0.081201802,0.064472543,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,147438,DB00186,10037855,38,16863,19,9989,0.585890486,1.184753665,0.665822403,2.176908574,0.733199935,DB0018610037855_,0.310336852,0.169534876,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,147443,DB00073,10043528,47,7359,25,6382,0.057329852,1.630345359,0.982014309,2.76749518,0.138426893,DB0007310043528_,1.977412943,0.488791869,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rituximab,DB00073
,147448,DB00480,10043528,31,67397,26,67636,0.511055264,1.196532604,0.687435533,2.098420026,0.671385827,DB0048010043528_,0.398411305,0.179427877,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,147450,DB00904,10043528,36,23033,15,14441,0.19742682,1.504711727,0.80317254,2.959268141,0.345911476,DB0090410043528_,1.061572386,0.408601336,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,147453,DB08932,10016825,563,18880,168,6429,0.142616412,1.141135912,0.956474612,1.36718729,0.273489295,DB0893210016825_,1.296492799,0.13202418,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,macitentan,DB08932
,147455,DB00425,10010144,1182,11513,638,6846,0.059830424,1.101669911,0.995002652,1.220497777,0.143179837,DB0042510010144_,1.943653834,0.096827129,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,147456,DB00210,10013709,77,808,28,321,0.735510517,1.092432974,0.685473491,1.783906826,0.847227922,DB0021010013709_,0.165785528,0.088407295,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,adapalene,DB00210
,147462,DB00343,10047942,60,8676,32,5063,0.745414994,1.094187122,0.699997074,1.739452966,0.854722582,DB0034310047942_,0.156978328,0.090011733,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,diltiazem,DB00343
,147465,DB06605,10002855,121,13952,52,12981,1.74580170154638e-06,2.164823606,1.550415648,3.060034783,2.34963634025328e-05,DB0660510002855_,10.6586649,0.772338883,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,apixaban,DB06605
,147470,DB06605,10064385,33,14040,19,13014,0.097795107,1.609884637,0.888477255,2.998275174,0.207561418,DB0660510064385_,1.572327991,0.476162522,NA,10064385,Circumstance or information capable of leading to medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,147473,DB01306,10017577,63,4145,36,3830,0.025494824,1.616907601,1.054310247,2.513566533,0.074604112,DB0130610017577_,2.595559651,0.480515437,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,147482,DB00656,10028334,162,11851,64,6555,0.025029499,1.400055505,1.0403152,1.903526699,0.073516638,DB0065610028334_,2.610243534,0.336511882,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,147495,DB09153,10051792,145,7654,65,5634,0.000894299,1.641974915,1.214633492,2.240125393,0.00502496,DB0915310051792_,5.293337838,0.495899734,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium chloride,DB09153
,147507,DB00736,10061818,97,10494,50,5503,1,1.017325372,0.714780773,1.463587066,1,DB0073610061818_,0,0.017176999,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,147517,DB00331,10009887,48,24898,30,20722,0.255075108,1.331630964,0.826381018,2.177514059,0.415741791,DB0033110009887_,0.877690905,0.286404479,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,147533,DB00188,10016322,85,7801,67,8761,0.033632536,1.424738162,1.020630124,1.995826434,0.092656034,DB0018810016322_,2.378861201,0.353988051,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,147535,DB08910,10016322,160,16584,126,17362,0.017491034,1.329396498,1.044967806,1.69427928,0.055634129,DB0891010016322_,2.888958432,0.284725078,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,147536,DB08910,10048959,282,16462,264,17224,0.210757292,1.11762204,0.940245149,1.328801634,0.362146527,DB0891010048959_,1.015706378,0.11120325,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,147539,DB08932,10028836,149,19294,38,6559,0.128497238,1.332930698,0.926950632,1.959307432,0.253493687,DB0893210028836_,1.372416358,0.28738005,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,147541,DB08932,10036018,70,19373,17,6580,0.265864565,1.398507767,0.813644293,2.537124903,0.427965588,DB0893210036018_,0.848712488,0.335405787,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,macitentan,DB08932
,147546,DB00451,10051792,104,47167,23,15396,0.098693147,1.475921915,0.932260113,2.431423174,0.20886871,DB0045110051792_,1.566049406,0.389282822,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,147547,DB00455,10051792,70,9331,34,5084,0.608368889,1.121757175,0.733381003,1.745747361,0.751034851,DB0045510051792_,0.286303222,0.114896362,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,147549,DB00761,10051792,35,15272,18,8607,0.886251936,1.095857421,0.603623048,2.056672554,0.952702357,DB0076110051792_,0.048452746,0.09153709,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,147554,DB01241,10013573,29,914,31,1040,0.895661635,1.064382662,0.613732898,1.841174702,0.95615204,DB0124110013573_,0.044838341,0.062394971,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,gemfibrozil,DB01241
,147559,DB00343,10048294,51,8685,29,5066,1,1.025810641,0.637029078,1.68088584,1,DB0034310048294_,0,0.025483169,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,diltiazem,DB00343
,147573,DB00186,10012374,47,16854,17,9991,0.091863522,1.638880287,0.92317254,3.046288348,0.198221293,DB0018610012374_,1.618371232,0.494013257,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,147577,DB00186,10013663,55,16846,15,9993,0.006123557,2.174996899,1.210752298,4.147703327,0.024059445,DB0018610013663_,3.727227633,0.777027239,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,147578,DB00333,10013663,27,3044,33,3119,0.519077046,0.838365367,0.483628698,1.441663379,0.678296801,DB0033310013663_,0.388170327,-0.176301275,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,methadone,DB00333
,147596,DB06605,10037867,30,14043,21,13012,0.330788729,1.323672907,0.732600629,2.433805523,0.499499152,DB0660510037867_,0.694149378,0.280410378,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,apixaban,DB06605
,147597,DB06228,10006784,33,15879,19,16057,0.05219223,1.756270018,0.969383645,3.270642491,0.129147824,DB0622810006784_,2.046797606,0.563192252,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,147598,DB06605,10006784,49,14024,22,13011,0.004106545,2.066260682,1.225220193,3.590959871,0.017446973,DB0660510006784_,4.048589125,0.72574054,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,147599,DB06605,10020937,129,13944,64,12969,3.33784634328433e-05,1.874637183,1.377331159,2.57346861,0.000311726,DB0660510020937_,8.073385865,0.628415138,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,147600,DB05676,10016100,52,47077,26,25303,0.813064751,1.074967177,0.658957286,1.793976056,0.89954571,DB0567610016100_,0.10586541,0.072290128,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,147611,DB00390,10037087,41,4104,28,3273,0.545537189,1.167762654,0.70318162,1.965344281,0.700287892,DB0039010037087_,0.356263754,0.155089657,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,digoxin,DB00390
,147634,DB01068,10049414,40,13723,30,6810,0.097982162,0.661660347,0.401552647,1.101153532,0.207857724,DB0106810049414_,1.570901452,-0.413002925,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,147656,DB00627,10011906,24,1305,56,1543,0.005969093,0.506853849,0.298671403,0.836640307,0.023565278,DB0062710011906_,3.74798093,-0.679532583,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,niacin,DB00627
,147658,DB00046,10029354,18,5441,38,4654,0.001175848,0.405202784,0.217390306,0.72878259,0.006296022,DB0004610029354_,5.067837259,-0.903367636,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,insulin lispro,DB00046
,147660,DB00688,10029354,78,6412,65,5313,1,0.994323228,0.704723486,1.406894389,1,DB0068810029354_,0,-0.005692946,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,mycophenolate mofetil,DB00688
,147692,DB00572,10011224,51,2851,36,2090,0.91308014,1.038521492,0.661971577,1.644468688,0.961104948,DB0057210011224_,0.039671669,0.03779806,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atropine,DB00572
,147707,DB00678,10015090,104,15495,69,10655,0.876695358,1.036446718,0.756408748,1.427746373,0.947355032,DB0067810015090_,0.054081354,0.035798246,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,147715,DB09140,10021143,195,3546,103,1695,0.445415823,0.904977795,0.703929894,1.1687871,0.613372884,DB0914010021143_,0.488782235,-0.099844871,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,147716,DB00572,10025482,87,2815,47,2079,0.092441183,1.367007105,0.943317678,2.002417515,0.199116323,DB0057210025482_,1.613866086,0.312623755,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,atropine,DB00572
,147717,DB00421,10028411,155,8748,43,5209,3.63255344627528e-06,2.146283973,1.51929309,3.08879826,4.47091437230114e-05,DB0042110028411_,10.01533252,0.763737962,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,spironolactone,DB00421
,147728,DB00390,10036790,57,4088,19,3282,0.000665658,2.408200387,1.408036586,4.296491716,0.00393143,DB0039010036790_,5.538751991,0.878879741,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,147730,DB00678,10036790,80,15519,27,10697,0.001048475,2.042262355,1.304637493,3.289229849,0.005733727,DB0067810036790_,5.161389587,0.714058191,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,147732,DB00203,10037368,52,13826,22,8916,0.120343939,1.524215166,0.90889414,2.637508892,0.241819466,DB0020310037368_,1.419563838,0.421479632,NA,10037368,Pulmonary congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,147740,DB00887,10037660,72,2269,48,1767,0.455288077,1.168089592,0.794997966,1.729455674,0.622807552,DB0088710037660_,0.473517713,0.155369587,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,147742,DB00374,10037833,62,17654,14,5710,0.28394826,1.432329262,0.792216458,2.772843843,0.448451601,DB0037410037833_,0.801954515,0.359301974,NA,10037833,Rales,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,147750,DB00203,10039101,154,13724,60,8878,0.000707316,1.660329471,1.222931767,2.279289174,0.004130103,DB0020310039101_,5.489453017,0.507016059,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,147751,DB00374,10039101,156,17560,25,5699,0.000649381,2.024985857,1.320276535,3.228639702,0.003847834,DB0037410039101_,5.560244858,0.705562716,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,147752,DB00390,10039101,41,4104,11,3290,0.000648847,2.987510858,1.505269214,6.455256582,0.003845101,DB0039010039101_,5.560955427,1.094440552,female,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,147753,DB00559,10039101,67,9592,18,3288,0.45345352,1.275889609,0.747966723,2.285384968,0.620992824,DB0055910039101_,0.476435752,0.243643668,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bosentan,DB00559
,147755,DB00678,10039101,102,15497,37,10687,0.000681742,1.901056813,1.292241156,2.851849684,0.00400348,DB0067810039101_,5.520591175,0.642409949,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,147756,DB00761,10039101,108,15199,37,8588,0.008999785,1.649265101,1.124634314,2.467601948,0.032716872,DB0076110039101_,3.419864367,0.500329795,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,147769,DB00203,10040742,78,13800,32,8906,0.031145109,1.573039811,1.029072381,2.456093691,0.087224889,DB0020310040742_,2.43926557,0.453009933,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,147797,DB00421,10046306,85,8818,28,5224,0.006068795,1.798361857,1.159283418,2.867946691,0.02388177,DB0042110046306_,3.734639852,0.586876171,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,spironolactone,DB00421
,147799,DB09140,10046306,92,3649,27,1771,0.022522749,1.653609287,1.062130483,2.652528182,0.067774522,DB0914010046306_,2.691568938,0.502960346,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,oxygen,DB09140
,147814,DB00421,10047924,45,8858,25,5227,0.901459339,1.062159842,0.636670872,1.809812471,0.95698137,DB0042110047924_,0.043971355,0.060304422,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,147816,DB00678,10047924,73,15526,31,10693,0.027339007,1.621783482,1.050961173,2.556781971,0.078730779,DB0067810047924_,2.541721104,0.483526458,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,147843,DB00321,10037844,177,7270,49,2801,0.042367262,1.391641989,1.005731667,1.95691523,0.110412797,DB0032110037844_,2.203529238,0.330484337,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,amitriptyline,DB00321
,147844,DB00333,10037844,30,3041,34,3118,0.708066659,0.90471793,0.533346135,1.527514248,0.825584719,DB0033310037844_,0.191663393,-0.100132064,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,methadone,DB00333
,147845,DB09037,10037844,87,2439,94,2741,0.82045145,1.040140573,0.763883868,1.414946517,0.904351949,DB0903710037844_,0.10053667,0.039355871,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,pembrolizumab,DB09037
,147881,DB01261,10046571,84,3697,54,3249,0.08459117,1.366991851,0.956408286,1.968129009,0.186057396,DB0126110046571_,1.681700071,0.312612597,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,sitagliptin,DB01261
,147883,DB08895,10040829,66,28048,16,6630,0.888638193,0.975068312,0.557882775,1.805337195,0.953864445,DB0889510040829_,0.047233708,-0.025247747,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,147897,DB00437,10028735,47,6874,32,11514,9.40278716631391e-05,2.460057268,1.535275967,3.987762524,0.000756511,DB0043710028735_,7.186793011,0.900184629,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,147902,DB00186,10023547,72,16829,48,9960,0.57021278,0.88776024,0.607139639,1.308210011,0.720856239,DB0018610023547_,0.327315553,-0.119053572,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,lorazepam,DB00186
,147907,DB01076,10023547,99,25648,103,25480,0.778094927,0.954855583,0.716858639,1.271373223,0.879072925,DB0107610023547_,0.128887421,-0.046195171,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,atorvastatin,DB01076
,147954,DB00996,10011781,133,38820,32,22393,2.09747331792275e-06,2.397464766,1.619040584,3.647434328,2.76420587423411e-05,DB0099610011781_,10.49617208,0.874411832,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,gabapentin,DB00996
,147966,DB08868,10028334,244,8958,65,2446,0.943989289,1.025000192,0.773645761,1.37435321,0.982722423,DB0886810028334_,0.017428576,0.0246928,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,fingolimod,DB08868
,147977,DB08868,10047626,52,9150,21,2490,0.150937364,0.673874317,0.398063192,1.18016769,0.285208196,DB0886810047626_,1.254535854,-0.394711659,NA,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,fingolimod,DB08868
,147981,DB00996,10048592,72,38881,37,22388,0.619417884,1.120506667,0.743446479,1.714365885,0.76019139,DB0099610048592_,0.274185049,0.113780964,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,147983,DB00273,10049848,68,8413,18,2175,0.893844705,0.976663799,0.572715372,1.749050874,0.95581177,DB0027310049848_,0.045194278,-0.023612802,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,147984,DB00843,10049848,36,2158,34,2139,0.904282468,1.049506575,0.635657224,1.736001646,0.957497529,DB0084310049848_,0.043432138,0.048320125,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,donepezil,DB00843
,147985,DB00273,10057668,58,8423,39,2154,1.07134730960561e-05,0.380372519,0.248408604,0.587985013,0.000115199,DB0027310057668_,9.068850609,-0.966604194,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,148042,DB00136,10021097,48,2044,41,1641,0.829316325,0.939942262,0.603252965,1.470328804,0.910379403,DB0013610021097_,0.09389384,-0.061936829,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,calcitriol,DB00136
,148043,DB01592,10021097,134,6142,59,3008,0.535949393,1.112279855,0.810264409,1.542540553,0.692376074,DB0159210021097_,0.367626011,0.106411832,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,iron,DB01592
,148045,DB00455,10022000,108,9293,42,5076,0.070869023,1.404528262,0.973168768,2.060214401,0.162831491,DB0045510022000_,1.815039409,0.339701489,NA,10022000,Influenza,10021881,Infections and infestations,Infec,loratadine,DB00455
,148046,DB00695,10022000,342,27707,175,20353,9.53878355324142e-05,1.435566627,1.191874548,1.734049468,0.000765358,DB0069510022000_,7.175166781,0.361559633,NA,10022000,Influenza,10021881,Infections and infestations,Infec,furosemide,DB00695
,148049,DB01592,10022000,81,6195,31,3036,0.266313283,1.280430088,0.834742515,2.009471757,0.428473676,DB0159210022000_,0.847525977,0.247196028,NA,10022000,Influenza,10021881,Infections and infestations,Infec,iron,DB01592
,148052,DB01592,10025482,225,6051,74,2993,0.002597885,1.503878258,1.147096867,1.990506928,0.01202044,DB0159210025482_,4.421146784,0.408047277,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,148063,DB01592,10037660,135,6141,74,2993,0.4137144,0.889155381,0.662395579,1.201326731,0.583050936,DB0159210037660_,0.539480727,-0.117483277,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,148074,DB00956,10000381,32,5782,37,3430,0.005912499,0.513081193,0.308827924,0.848265691,0.023396316,DB0095610000381_,3.755176705,-0.667321176,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocodone,DB00956
,148082,DB01590,10000060,31,4707,22,2845,0.571842742,0.851705131,0.476419512,1.547167736,0.721961933,DB0159010000060_,0.325782865,-0.160514902,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,everolimus,DB01590
,148083,DB01590,10010774,79,4659,93,2774,1.0663436081658e-05,0.505811492,0.368515234,0.692896674,0.000114778,DB0159010010774_,9.072508798,-0.681591225,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,everolimus,DB01590
,148084,DB00112,10021015,100,5833,25,4066,8.56303129381341e-07,2.787981636,1.780330062,4.520359307,1.25113550615834e-05,DB0011210021015_,11.28887392,1.025317906,female,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,bevacizumab,DB00112
,148095,DB00264,10054112,264,29343,235,24657,0.527675209,0.944028982,0.788128822,1.131217102,0.685234831,DB0026410054112_,0.377993681,-0.057598412,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,metoprolol,DB00264
,148097,DB01592,10054112,85,6191,44,3023,0.777202913,0.94329319,0.64620838,1.393942904,0.878524891,DB0159210054112_,0.129511038,-0.058378132,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,iron,DB01592
,148098,DB04844,10054112,49,627,38,431,0.65033473,0.886480782,0.557740278,1.417922079,0.785013468,DB0484410054112_,0.242054405,-0.120495833,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,tetrabenazine,DB04844
,148099,DB11089,10054112,119,10056,79,8328,0.132274157,1.247469157,0.929310704,1.682215691,0.259020057,DB1108910054112_,1.350849781,0.221116824,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,docusate,DB11089
,148101,DB00678,10047461,36,15563,20,10704,0.49747026,1.237995879,0.697295754,2.258396947,0.659595353,DB0067810047461_,0.416128734,0.213493846,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,losartan,DB00678
,148115,DB00246,10013573,48,1026,12,689,0.001761646,2.684847545,1.392370461,5.594959943,0.008757446,DB0024610013573_,4.737850932,0.987623946,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ziprasidone,DB00246
,148140,DB00184,10069327,49,1245,26,956,0.154712696,1.446912428,0.874452954,2.444544557,0.290379751,DB0018410069327_,1.236565727,0.369431926,NA,10069327,Product quality issue,10077536,Product issues,Prod,nicotine,DB00184
,148143,DB08932,10048669,45,19398,23,6574,0.123627581,0.663078748,0.392453464,1.149160035,0.246562429,DB0893210048669_,1.400140057,-0.410861521,NA,10048669,Terminal state,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,148144,DB00169,10002948,70,38621,35,18140,0.754194951,0.93938743,0.617278244,1.453226167,0.861838722,DB0016910002948_,0.148687124,-0.062527287,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,148145,DB00186,10002948,53,16848,21,9987,0.147763714,1.496018638,0.886599547,2.61285715,0.280887307,DB0018610002948_,1.269801734,0.402807338,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,148149,DB00497,10002948,33,19234,28,16347,1,1.001669258,0.586648296,1.721422748,1,DB0049710002948_,0,0.001667867,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,148151,DB01104,10002948,33,15430,17,7269,0.762892645,0.914485476,0.494572016,1.751753687,0.868699858,DB0110410002948_,0.140757602,-0.089393694,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,148153,DB01234,10002948,55,31570,38,32850,0.061195893,1.506032737,0.977856233,2.341395191,0.145627997,DB0123410002948_,1.926699878,0.409478867,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,148154,DB00264,10013887,64,29543,60,24832,0.588418903,0.896575883,0.620194923,1.297636402,0.735348779,DB0026410013887_,0.307410363,-0.109172346,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,148158,DB00544,10013887,35,2400,17,2636,0.005085992,2.260934941,1.229377304,4.315526806,0.020736048,DB0054410013887_,3.875881627,0.815778418,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,fluorouracil,DB00544
,148160,DB00904,10013887,55,23014,39,14417,0.596009606,0.883453451,0.575242415,1.368478423,0.741460234,DB0090410013887_,0.299133748,-0.123916675,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,148162,DB01234,10013887,54,31571,40,32848,0.121075982,1.404591011,0.915754283,2.170514012,0.242965185,DB0123410013887_,1.414837116,0.339746165,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,148166,DB00433,10029331,164,7492,135,5885,0.723866282,0.954219578,0.753198036,1.210598787,0.837715468,DB0043310029331_,0.177076773,-0.046861468,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,148167,DB00482,10029331,70,8189,24,3047,0.816032495,1.085237993,0.672601279,1.808155006,0.901368442,DB0048210029331_,0.10384118,0.081799311,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,148168,DB00186,10044390,45,16856,17,9991,0.116264776,1.568956953,0.879975729,2.925699821,0.235531379,DB0018610044390_,1.445911129,0.450411038,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,148170,DB00497,10044390,39,19228,37,16338,0.646441844,0.895631488,0.556082336,1.444887466,0.781892411,DB0049710044390_,0.24603813,-0.110226236,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,148172,DB01234,10044390,72,31553,59,32829,0.189580659,1.269681077,0.88710847,1.823535807,0.336005368,DB0123410044390_,1.090628142,0.238765749,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,148174,DB00581,10016256,155,1958,132,1937,0.245119942,1.161605633,0.906960435,1.48939081,0.403897798,DB0058110016256_,0.906593409,0.149803215,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lactulose,DB00581
,148176,DB00230,10001497,112,19562,61,8590,0.185349235,0.806279118,0.584433938,1.121411243,0.330657299,DB0023010001497_,1.10667279,-0.215325296,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,148177,DB00514,10001497,16,2150,34,1502,0.000221475,0.328853426,0.168856492,0.614877045,0.001569767,DB0051410001497_,6.456828277,-1.112143141,male,10001497,Agitation,10037175,Psychiatric disorders,Psych,dextromethorphan,DB00514
,148179,DB00814,10001497,30,8257,22,3393,0.045953534,0.560401956,0.312086658,1.021126966,0.117407528,DB0081410001497_,2.14210425,-0.579100974,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,meloxicam,DB00814
,148200,DB00814,10024264,53,8234,17,3398,0.42948868,1.286534764,0.732029276,2.373796217,0.597965583,DB0081410024264_,0.514222081,0.251952374,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,148229,DB00181,10061024,28,9828,30,5841,0.028883994,0.554746964,0.318964474,0.961889039,0.082224052,DB0018110061024_,2.498307413,-0.58924319,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,baclofen,DB00181
,148258,DB01076,10050256,58,25689,36,25547,0.029695497,1.60218171,1.038881857,2.501038946,0.084038129,DB0107610050256_,2.476484668,0.471366269,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,148277,DB08932,10064685,66,19377,23,6574,0.903080567,0.97355202,0.597041362,1.641491954,0.957326661,DB0893210064685_,0.043610607,-0.02680402,NA,10064685,Device occlusion,10077536,Product issues,Prod,macitentan,DB08932
,148285,DB00115,10033645,40,18385,23,10449,1,0.988420883,0.577237424,1.730399442,1,DB0011510033645_,0,-0.011646677,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,148290,DB01137,10007515,37,7735,48,5545,0.007786136,0.552626319,0.349404402,0.867777072,0.029134969,DB0113710007515_,3.535816151,-0.593073241,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,levofloxacin,DB01137
,148291,DB00472,10044066,29,10730,36,4276,6.27413685830905e-06,0.321031179,0.189615444,0.539265563,7.22363939205665e-05,DB0047210044066_,9.535566568,-1.136217028,male,10044066,Torsade de pointes,10007541,Cardiac disorders,Card,fluoxetine,DB00472
,148297,DB01609,10040642,110,1474,46,1297,2.20562582584521e-05,2.103640242,1.465205578,3.061625519,0.000217134,DB0160910040642_,8.434994213,0.743669292,NA,10040642,Sickle cell anaemia with crisis,10005329,Blood and lymphatic system disorders,Blood,deferasirox,DB01609
,148301,DB00338,10021114,65,33609,30,22242,0.115419963,1.433862362,0.916526565,2.29051427,0.234298469,DB0033810021114_,1.451159466,0.360371756,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,omeprazole,DB00338
,148303,DB09037,10021114,34,2492,36,2799,0.81085221,1.060816464,0.641810263,1.749987895,0.898226748,DB0903710021114_,0.107332739,0.059038861,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,pembrolizumab,DB09037
,148309,DB00188,10017944,42,7844,31,8797,0.078934384,1.519392222,0.931685234,2.50262199,0.176555085,DB0018810017944_,1.734122354,0.418310401,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,148310,DB00184,10025482,39,1255,13,969,0.007062562,2.315518763,1.201905235,4.754683176,0.02697395,DB0018410025482_,3.612883699,0.83963375,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,nicotine,DB00184
,148318,DB00874,10007559,48,3287,40,1936,0.119343655,0.706855028,0.453039261,1.108019836,0.240342321,DB0087410007559_,1.425691032,-0.346929687,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,guaifenesin,DB00874
,148329,DB00196,10021143,38,5045,41,3244,0.027204223,0.596021796,0.372183526,0.952315649,0.07844977,DB0019610021143_,2.545296728,-0.517478041,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluconazole,DB00196
,148344,DB00874,10047924,41,3294,17,1959,0.222484564,1.434226391,0.794496215,2.700308911,0.37656484,DB0087410047924_,0.97666503,0.360625604,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,guaifenesin,DB00874
,148354,DB01233,10061818,56,3365,35,1691,0.315181575,0.804094898,0.515583761,1.269395841,0.482773673,DB0123310061818_,0.728207321,-0.218037985,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,148361,DB00413,10019063,58,2141,114,1093,4.71382625453507e-17,0.259843705,0.184449576,0.362788843,3.62289248831737e-15,DB0041310019063_,33.25150366,-1.347674963,male,10019063,Hallucination,10037175,Psychiatric disorders,Psych,pramipexole,DB00413
,148368,DB00471,10000059,191,13998,55,5410,0.062316673,1.342100203,0.987814364,1.84933041,0.147773354,DB0047110000059_,1.91207557,0.294235703,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,148380,DB00996,10019304,46,38907,21,22404,0.446635824,1.261376132,0.737413595,2.225920607,0.614378321,DB0099610019304_,0.487144382,0.232203294,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,gabapentin,DB00996
,148382,DB00227,10028334,51,2416,17,1786,0.004104629,2.217315484,1.254400013,4.109988028,0.017445254,DB0022710028334_,4.048687648,0.796297223,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,lovastatin,DB00227
,148383,DB00455,10028334,145,9256,65,5053,0.216022483,1.21775799,0.900889772,1.661340224,0.368639289,DB0045510028334_,0.997936651,0.197011455,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,148385,DB00455,10042772,63,9338,44,5074,0.222850816,0.778041352,0.520194397,1.172721924,0.377011887,DB0045510042772_,0.975478561,-0.250975605,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,148421,DB00480,10000369,22,67406,31,67631,0.271623102,0.712051076,0.392771396,1.27021863,0.434441599,DB0048010000369_,0.833693753,-0.339605634,NA,10000369,Accident,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,148441,DB00588,10041569,34,16490,17,8451,1,1.024984486,0.556592435,1.957573389,1,DB0058810041569_,0,0.024677477,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,148455,DB00706,10001949,10,1065,64,15861,0.025546713,2.326857808,1.062031601,4.578723684,0.07471021,DB0070610001949_,2.594138521,0.844518777,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,148489,DB01050,10039020,18,18090,32,9339,1.76728098520068e-05,0.290405869,0.153409651,0.533561672,0.00017901,DB0105010039020_,8.628071348,-1.236475785,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,148492,DB04861,10013709,92,1873,63,1324,0.86778618,1.032273572,0.735002584,1.457444883,0.940796702,DB0486110013709_,0.061028207,0.031763721,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,nebivolol,DB04861
,148495,DB00395,10022437,71,2113,24,712,1,0.996845989,0.614264227,1.669577108,1,DB0039510022437_,0,-0.003158995,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,carisoprodol,DB00395
,148496,DB00972,10022437,46,2458,20,1159,0.894160386,1.084474168,0.625465283,1.944868251,0.955860142,DB0097210022437_,0.045143671,0.081095232,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,azelastine,DB00972
,148517,DB00395,10053762,47,2137,18,718,0.664916957,0.877350255,0.496205421,1.615971519,0.796052936,DB0039510053762_,0.228089593,-0.130848988,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,carisoprodol,DB00395
,148518,DB00972,10053762,51,2453,25,1154,0.901253621,0.959724722,0.580390876,1.625120698,0.956927891,DB0097210053762_,0.044027239,-0.041108784,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,azelastine,DB00972
,148540,DB01118,10009802,35,3028,24,4685,0.002009165,2.256150095,1.301478591,3.973001973,0.009764428,DB0111810009802_,4.629009316,0.813659863,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,amiodarone,DB01118
,148555,DB00410,10035664,71,1534,50,959,0.566414084,0.887774861,0.603709156,1.313842023,0.717809428,DB0041010035664_,0.331551165,-0.119037103,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,mupirocin,DB00410
,148559,DB01307,10035664,91,2433,74,1995,1,1.008346574,0.729344922,1.39786117,1,DB0130710035664_,0,0.008311934,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,insulin detemir,DB01307
,148561,DB08816,10035664,21,1130,33,1869,0.88773277,1.052506722,0.575663058,1.884729456,0.953461196,DB0881610035664_,0.047656551,0.051174673,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ticagrelor,DB08816
,148564,DB00455,10038695,56,9345,42,5076,0.136947171,0.724281447,0.476090417,1.109340882,0.265425436,DB0045510038695_,1.326421321,-0.322575223,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,148568,DB00758,10038695,70,8230,56,10018,0.019584949,1.521513532,1.054038098,2.205103252,0.060803212,DB0075810038695_,2.800112658,0.419705584,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,148569,DB00788,10038695,37,9319,33,5028,0.043786038,0.604939207,0.367547106,0.999559158,0.113156969,DB0078810038695_,2.178979322,-0.50262731,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,naproxen,DB00788
,148570,DB01306,10038695,30,4178,31,3835,0.700223196,0.888307205,0.518395019,1.520238184,0.819879108,DB0130610038695_,0.198598379,-0.118437644,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin aspart,DB01306
,148577,DB08868,10005734,62,9140,15,2496,0.780927159,1.128740726,0.633235651,2.140319612,0.880700697,DB0886810005734_,0.127037442,0.12110261,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,fingolimod,DB08868
,148578,DB08868,10016825,50,9152,12,2499,0.758667009,1.137716517,0.596285409,2.350902909,0.865387738,DB0886810016825_,0.144577621,0.129023198,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,fingolimod,DB08868
,148582,DB01156,10035528,45,13577,21,6307,1,0.99543366,0.580199012,1.760718805,1,DB0115610035528_,0,-0.004576797,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,bupropion,DB01156
,148586,DB08868,10040741,51,9151,23,2488,0.047005212,0.602901487,0.360999964,1.035802022,0.119467414,DB0886810040741_,2.124711627,-0.506001467,NA,10040741,Sinus bradycardia,10007541,Cardiac disorders,Card,fingolimod,DB08868
,148648,DB00186,10070863,516,16385,347,9661,0.062792814,0.876798718,0.761938185,1.00991927,0.148661032,DB0018610070863_,1.906086515,-0.131477825,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,148649,DB00230,10070863,179,19495,103,8548,0.031867416,0.761989202,0.5938363,0.982084528,0.088812492,DB0023010070863_,2.421227963,-0.271822895,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,148663,DB01050,10000060,122,17986,43,9328,0.03191906,1.471429885,1.030485415,2.136597775,0.088942276,DB0105010000060_,2.41976771,0.386234639,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,148738,DB00601,10012735,44,861,13,898,2.15446017958306e-05,3.528010616,1.850392599,7.191330972,0.000212815,DB0060110012735_,8.455088827,1.260734147,female,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,linezolid,DB00601
,148758,DB00331,10008469,134,24812,72,20680,0.002514441,1.551157656,1.155596851,2.096651427,0.011712226,DB0033110008469_,4.447122048,0.439001527,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,148761,DB00678,10023676,30,15569,22,10702,0.887859573,0.937354896,0.522586418,1.706353802,0.953538943,DB0067810023676_,0.047575012,-0.06469331,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,148762,DB00999,10023676,36,21394,57,12182,1.23875193122584e-06,0.359639324,0.229997491,0.555769558,1.7333294922689e-05,DB0099910023676_,10.96288134,-1.022653629,male,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,148779,DB00341,10016766,39,11366,22,5046,0.404355152,0.786993836,0.454696361,1.395153111,0.574093238,DB0034110016766_,0.55496346,-0.239534863,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,148808,DB00996,10005956,52,38901,23,22402,0.337539108,1.301971841,0.782592418,2.229547643,0.50673761,DB0099610005956_,0.679761943,0.263879916,NA,10005956,Bone disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,148814,DB00287,10016173,44,1357,24,793,0.898509514,1.07133357,0.63186259,1.856950884,0.956423691,DB0028710016173_,0.044554273,0.0689042,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,travoprost,DB00287
,148816,DB00698,10016173,123,3025,15,414,0.789460041,1.122249981,0.646626677,2.08650095,0.885865533,DB0069810016173_,0.121190109,0.115335582,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,nitrofurantoin,DB00698
,148950,DB00537,10040753,110,7447,33,4265,0.000830747,1.908950577,1.280743647,2.914370103,0.004724912,DB0053710040753_,5.354906268,0.646553655,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,148965,DB11133,10013968,101,2330,55,1519,0.316118101,1.197107369,0.847790856,1.705495002,0.483794135,DB1113310013968_,0.726095803,0.179908121,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omega-3 fatty acids,DB11133
,148966,DB00390,10033557,108,4037,26,3275,1.1699840638995e-09,3.36920813,2.173280102,5.402524843,3.20344074162482e-08,DB0039010033557_,17.25645528,1.214677741,female,10033557,Palpitations,10007541,Cardiac disorders,Card,digoxin,DB00390
,148971,DB00338,10003997,36,33638,34,22238,0.143370603,0.70000623,0.425613343,1.153509435,0.274551675,DB0033810003997_,1.292615785,-0.356666044,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,omeprazole,DB00338
,148985,DB00203,10052264,231,13647,57,8881,1.47174493946965e-12,2.637201452,1.963251364,3.593556295,6.43139081196337e-11,DB0020310052264_,23.46724521,0.969718299,NA,10052264,Catheter site erythema,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,148990,DB09140,10052264,40,3701,10,1788,0.068040513,1.932249683,0.946853315,4.343199391,0.157766838,DB0914010052264_,1.846637045,0.658684963,NA,10052264,Catheter site erythema,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,148994,DB00695,10052268,54,27995,7,20521,3.11304841389901e-07,5.654590039,2.564537476,14.73885096,5.05257657050543e-06,DB0069510052268_,12.19561223,1.732467612,female,10052268,Catheter site pain,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,149007,DB00203,10067996,74,13804,15,8923,6.11654908775113e-06,3.188785692,1.812729991,5.986093953,7.05064847942287e-05,DB0020310067996_,9.559805869,1.159640184,female,10067996,Catheter site swelling,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,149044,DB00343,10003246,53,8683,11,5084,0.000992124,2.820915704,1.45453953,5.994381243,0.005466069,DB0034310003246_,5.209195548,1.03706155,female,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,diltiazem,DB00343
,149045,DB00761,10003246,92,15215,24,8601,0.000437174,2.166909292,1.369212928,3.554708825,0.002760628,DB0076110003246_,5.892297149,0.773301863,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,149048,DB06724,10003246,65,7864,7,3912,6.49627243429542e-06,4.619391996,2.116309655,11.95242167,7.43866351276215e-05,DB0672410003246_,9.506234268,1.530263094,female,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,149050,DB08895,10003246,242,27872,57,6589,1,1.00367217,0.748313316,1.365889752,1,DB0889510003246_,0,0.003665444,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,149054,DB00695,10014011,61,27988,26,20502,0.022080789,1.718599583,1.069086952,2.835253337,0.066819522,DB0069510014011_,2.705760001,0.541509763,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,149060,DB08895,10017577,355,27759,78,6568,0.580534417,1.076837384,0.839290471,1.396391597,0.728996138,DB0889510017577_,0.316086845,0.074028397,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,149061,DB00678,10021789,144,15455,63,10661,0.002235485,1.576678376,1.163505014,2.157422056,0.01065163,DB0067810021789_,4.542042356,0.455320341,NA,10021789,Infection,10021881,Infections and infestations,Infec,losartan,DB00678
,149063,DB06724,10021789,70,7859,39,3880,0.540935577,0.886145305,0.589464184,1.349354262,0.696380256,DB0672410021789_,0.361859423,-0.120874341,NA,10021789,Infection,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,149065,DB08895,10021789,677,27437,140,6506,0.149796136,1.146663893,0.952508867,1.38837208,0.283656321,DB0889510021789_,1.25999191,0.136856764,NA,10021789,Infection,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,149066,DB00343,10022000,113,8623,38,5057,0.00286309,1.74386566,1.195633684,2.593792317,0.013020123,DB0034310022000_,4.341259199,0.556104293,NA,10022000,Influenza,10021881,Infections and infestations,Infec,diltiazem,DB00343
,149067,DB00761,10022000,200,15107,117,8508,0.768494256,0.962733667,0.761290402,1.2219731,0.873054912,DB0076110022000_,0.135756824,-0.037978471,NA,10022000,Influenza,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,149069,DB06724,10022000,81,7848,45,3874,0.567981312,0.888546067,0.608425785,1.312032865,0.71902082,DB0672410022000_,0.329864965,-0.118168785,NA,10022000,Influenza,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,149070,DB08895,10022000,553,27561,85,6561,0.000108588,1.548718255,1.22849178,1.972900132,0.000855753,DB0889510022000_,7.063529281,0.437427657,NA,10022000,Influenza,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,149073,DB08895,10028372,188,27926,37,6609,0.349358182,1.202487271,0.840668414,1.762244962,0.518953365,DB0889510028372_,0.655941255,0.184392138,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,149074,DB01261,10033371,102,3679,69,3234,0.103276855,1.299405438,0.944305616,1.796982549,0.215952599,DB0126110033371_,1.532696347,0.261906804,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,149075,DB06700,10033371,77,2148,16,602,0.308990976,1.348610633,0.772944759,2.495490002,0.476339568,DB0670010033371_,0.7416243,0.299074902,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,desvenlafaxine,DB06700
,149081,DB00678,10042682,85,15514,33,10691,0.004690612,1.774963522,1.173555095,2.742122208,0.019431479,DB0067810042682_,3.940860874,0.573779872,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,149085,DB01050,10022095,124,17984,32,9339,0.000246757,2.012221805,1.353745448,3.070976508,0.001716104,DB0105010022095_,6.367698925,0.699239487,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,149093,DB00668,10020937,75,10016,21,4282,0.093391845,1.526825566,0.929350385,2.612315911,0.200752751,DB0066810020937_,1.605681221,0.423190787,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,epinephrine,DB00668
,149094,DB00904,10020937,296,22773,120,14336,3.85966088727312e-05,1.552791273,1.250499514,1.938152248,0.000354044,DB0090410020937_,7.946090559,0.440054133,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,149099,DB00182,10000059,65,5129,31,2821,0.591728384,1.153249133,0.738876943,1.835262328,0.737975924,DB0018210000059_,0.303844078,0.142583292,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,amphetamine,DB00182
,149100,DB00182,10042464,48,5146,31,2821,0.480109297,0.848840151,0.527968529,1.382923119,0.644946741,DB0018210042464_,0.438587538,-0.163884389,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,149101,DB00193,10017413,80,19240,60,8642,0.003276139,0.598901679,0.42278228,0.852373146,0.014530212,DB0019310017413_,4.231525217,-0.512657835,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,tramadol,DB00193
,149102,DB00316,10017413,342,65132,204,36749,0.531883406,0.945904961,0.792592221,1.131140934,0.688748199,DB0031610017413_,0.372879533,-0.055613179,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,149103,DB00433,10017413,80,7576,63,5957,1,0.998474795,0.707428105,1.414510348,1,DB0043310017413_,0,-0.001526369,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,prochlorperazine,DB00433
,149104,DB00497,10017413,109,19158,91,16284,0.943319102,1.018114223,0.763051628,1.361127334,0.982219244,DB0049710017413_,0.017940733,0.017952115,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,oxycodone,DB00497
,149105,DB00904,10017413,174,22895,113,14343,0.761218885,0.964626417,0.756142071,1.234695455,0.867650712,DB0090410017413_,0.141966051,-0.036014385,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,ondansetron,DB00904
,149109,DB00203,10028391,118,13760,50,8888,0.013688795,1.524367569,1.085002734,2.169117307,0.045736619,DB0020310028391_,3.084856011,0.421579615,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,149110,DB00588,10028391,91,16433,30,8438,0.034249453,1.557527162,1.019924684,2.44047619,0.093897978,DB0058810028391_,2.365546424,0.443099411,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,149112,DB00374,10034474,140,17576,32,5692,0.075327087,1.416802723,0.958085802,2.153213873,0.170386169,DB0037410034474_,1.769687835,0.348402729,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,treprostinil,DB00374
,149113,DB00421,10034474,52,8851,24,5228,0.342890376,1.279767871,0.77377893,2.173533444,0.512240611,DB0042110034474_,0.668960822,0.246678711,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,spironolactone,DB00421
,149163,DB00169,10007697,84,38607,9,18166,5.66401351470398e-07,4.392031636,2.205682174,9.938772456,8.66761822572595e-06,DB0016910007697_,11.65591652,1.479791907,female,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,149164,DB00722,10007697,40,25363,19,26013,0.005784858,2.15917361,1.221282039,3.948327157,0.022995084,DB0072210007697_,3.772474809,0.769725561,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,149167,DB01373,10036018,75,22645,31,7350,0.258840191,0.785268786,0.509888079,1.23607634,0.419937315,DB0137310036018_,0.867649829,-0.241729218,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,calcium,DB01373
,149168,DB06643,10036018,72,52349,14,7501,0.325514289,0.736917391,0.411775854,1.415669813,0.493946605,DB0664310036018_,0.705327854,-0.305279481,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,denosumab,DB06643
,149170,DB00169,10057371,39,38652,11,18164,0.171138775,1.666126121,0.836599959,3.607877941,0.312398535,DB0016910057371_,1.16347555,0.510501244,NA,10057371,Hypoaesthesia oral,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,149186,DB00470,10002034,31,888,28,925,0.599639715,1.153184807,0.663251528,2.013186335,0.744258289,DB0047010002034_,0.295367142,0.142527512,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,dronabinol,DB00470
,149196,DB00470,10012174,35,884,30,923,0.451262211,1.218006348,0.719590047,2.073065903,0.618927038,DB0047010012174_,0.479767883,0.197215381,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,dronabinol,DB00470
,149199,DB00470,10013968,41,878,33,920,0.286995527,1.30166867,0.794883346,2.145964098,0.451811903,DB0047010013968_,0.794489331,0.263647033,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dronabinol,DB00470
,149221,DB00165,10047895,56,2089,41,1325,0.526681883,0.86636616,0.565180146,1.33776936,0.684423459,DB0016510047895_,0.379178461,-0.143447643,NA,10047895,Weight decreased,10022891,Investigations,Inv,pyridoxine,DB00165
,149226,DB00404,10051398,49,19843,52,9810,0.000176012,0.465862635,0.308547972,0.702426757,0.001295204,DB0040410051398_,6.649087388,-0.763864462,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,alprazolam,DB00404
,149229,DB13961,10051398,16,9441,41,6373,2.00215519180567e-06,0.263450798,0.137881004,0.480245644,2.64921465978414e-05,DB1396110051398_,10.53866222,-1.333888652,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fish oil,DB13961
,149230,DB00165,10061428,41,2104,27,1339,0.900529782,0.96638268,0.577235943,1.642058915,0.956698706,DB0016510061428_,0.044266769,-0.034195374,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,pyridoxine,DB00165
,149239,DB00437,10070863,30,6891,92,11454,0.003445947,0.542028404,0.346039929,0.827403896,0.015132688,DB0043710070863_,4.190898094,-0.612436874,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,allopurinol,DB00437
,149267,DB00321,10012373,39,7408,24,2826,0.067297371,0.619935875,0.362808603,1.079754366,0.156500478,DB0032110012373_,1.854696214,-0.478139234,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,149269,DB00497,10012373,88,19179,63,16312,0.326325694,1.188012559,0.849362107,1.669987593,0.494849331,DB0049710012373_,0.703501945,0.172281792,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,149294,DB00999,10016454,59,21371,12,12227,0.000462186,2.812892781,1.495267773,5.751288768,0.002892169,DB0099910016454_,5.845748514,1.034213413,female,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,149349,DB01136,10018867,19,9865,61,11054,2.4082539423978e-05,0.349051878,0.196731255,0.592756938,0.000233799,DB0113610018867_,8.361050751,-1.052534721,male,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,carvedilol,DB01136
,149354,DB01104,10042209,88,15375,26,7260,0.034598615,1.598168744,1.020801473,2.582196766,0.094623306,DB0110410042209_,2.357851467,0.468858439,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,149359,DB00005,10019641,33,128049,20,42399,0.037976838,0.546357283,0.304320388,1.004842035,0.101574274,DB0000510019641_,2.286964985,-0.604482153,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,etanercept,DB00005
,149380,DB00335,10015150,74,8392,36,5429,0.170825444,1.329764763,0.879999016,2.042379986,0.311934892,DB0033510015150_,1.164960794,0.285002056,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,atenolol,DB00335
,149386,DB00737,10016322,58,2743,12,920,0.162237625,1.620839709,0.85626387,3.33137317,0.300385022,DB0073710016322_,1.202690219,0.482944354,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,meclizine,DB00737
,149388,DB01062,10016322,77,4409,13,1732,0.002957127,2.326523642,1.279233116,4.577875199,0.013341619,DB0106210016322_,4.31686689,0.844375154,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,149398,DB00335,10018884,83,8383,59,5406,0.604451352,0.907206978,0.640754074,1.291377957,0.747793933,DB0033510018884_,0.29062783,-0.097384654,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,atenolol,DB00335
,149400,DB00727,10018884,52,3791,54,4119,0.845201689,1.046291942,0.699057972,1.564716233,0.921926606,DB0072710018884_,0.081289662,0.04525243,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,nitroglycerin,DB00727
,149402,DB01062,10018884,43,4443,19,1726,0.670092459,0.879212872,0.499827885,1.602206819,0.799790227,DB0106210018884_,0.223405802,-0.128728235,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,oxybutynin,DB01062
,149403,DB06637,10018884,37,6125,18,2001,0.161032588,0.671573505,0.371819805,1.256046895,0.298869661,DB0663710018884_,1.207747718,-0.398131805,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,dalfampridine,DB06637
,149404,DB08868,10018884,51,9151,15,2496,0.76471493,0.927369979,0.512248009,1.778952623,0.8701171,DB0886810018884_,0.139127479,-0.075402679,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,fingolimod,DB08868
,149405,DB11133,10018884,32,2399,22,1552,0.88865256,0.941012914,0.527824294,1.706566506,0.953864445,DB1113310018884_,0.047233708,-0.060798415,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,omega-3 fatty acids,DB11133
,149415,DB08868,10024384,84,9118,19,2492,0.546470392,1.208277113,0.726162105,2.110270873,0.701143399,DB0886810024384_,0.355042849,0.189195472,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,fingolimod,DB08868
,149425,DB01050,10025256,49,18059,11,9360,0.009225385,2.308734676,1.183696123,4.926964749,0.033370845,DB0105010025256_,3.400072663,0.836699615,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,ibuprofen,DB01050
,149458,DB00169,10029368,35,38656,17,18158,0.882809798,0.967122136,0.527321994,1.841288241,0.951043643,DB0016910029368_,0.050195326,-0.033430488,NA,10029368,Neutrophil count increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,149474,DB00331,10005728,37,24909,26,20726,0.529458883,1.184092856,0.697708932,2.037327774,0.686775895,DB0033110005728_,0.375747248,0.168976959,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,metformin,DB00331
,149486,DB01276,10025482,40,1977,22,1489,0.247364743,1.369264136,0.79054045,2.43008138,0.406589893,DB0127610025482_,0.899950235,0.314273469,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,149514,DB01261,10016807,37,3744,22,3281,0.189637258,1.473753916,0.844848985,2.628557469,0.336049035,DB0126110016807_,1.090498192,0.38781283,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,sitagliptin,DB01261
,149539,DB00864,10029444,40,6829,148,8244,1.26767738999391e-11,0.326306476,0.223758744,0.466236711,4.75673093447395e-10,DB0086410029444_,21.46629028,-1.119918229,male,10029444,Nocardiosis,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,149555,DB01222,10012174,102,9172,76,5329,0.117617393,0.77980172,0.572595374,1.065864271,0.237603134,DB0122210012174_,1.437153502,-0.248715596,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,budesonide,DB01222
,149557,DB00588,10051398,20,16504,35,8433,9.69000851456761e-06,0.291996713,0.159645195,0.520379161,0.000105773,DB0058810051398_,9.154213347,-1.231012734,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fluticasone propionate,DB00588
,149560,DB01136,10016288,28,9856,40,11075,0.394535687,0.786586748,0.466963316,1.308246251,0.564450703,DB0113610016288_,0.571902228,-0.240052267,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,carvedilol,DB01136
,149573,DB00264,10037867,44,29563,31,24861,0.487648726,1.193601659,0.736660058,1.955946932,0.651422988,DB0026410037867_,0.428596096,0.17697534,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,149609,DB00787,10058080,40,16960,47,17201,0.520715902,0.863161757,0.551419777,1.34531434,0.679796239,DB0078710058080_,0.385962174,-0.14715317,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,acyclovir,DB00787
,149610,DB01136,10058080,18,9866,42,11073,0.009133438,0.481032458,0.260440379,0.854571417,0.033111153,DB0113610058080_,3.407885115,-0.731820531,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,carvedilol,DB01136
,149627,DB00722,10040844,85,25318,71,25961,0.228926171,1.227580592,0.884766031,1.7076027,0.384616452,DB0072210040844_,0.955508669,0.205045234,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,149671,DB00669,10069868,178,6199,28,1069,0.764357847,1.096292629,0.728631632,1.705845549,0.869827189,DB0066910069868_,0.139460721,0.09193415,NA,10069868,Device issue,10077536,Product issues,Prod,sumatriptan,DB00669
,149701,DB00451,10064882,44,47227,7,15412,0.07453646,2.05113563,0.916350161,5.398864487,0.169070663,DB0045110064882_,1.777438526,0.718393606,NA,10064882,Procedural pain,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,149707,DB08910,10002855,66,16678,32,17456,0.00024752,2.15865221,1.394053037,3.405106095,0.001720726,DB0891010002855_,6.365009202,0.76948405,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,pomalidomide,DB08910
,149708,DB08910,10017885,61,16683,30,17458,0.000692265,2.12773221,1.352254671,3.414422657,0.004053955,DB0891010017885_,5.508062425,0.755056722,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,149710,DB08910,10017944,51,16693,45,17443,0.415540715,1.184245373,0.777020886,1.810315551,0.584748782,DB0891010017944_,0.536572956,0.169105756,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,149711,DB08910,10020772,93,16651,90,17398,0.65656102,1.079663247,0.798616514,1.460254497,0.790020726,DB0891010020772_,0.235696099,0.076649184,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,pomalidomide,DB08910
,149743,DB00999,10003246,143,21287,43,12196,0.000122292,1.90529656,1.345300602,2.747647822,0.000947791,DB0099910003246_,6.961376308,0.644637671,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,149746,DB00999,10031282,45,21385,10,12229,0.004642238,2.573256784,1.277916816,5.728670336,0.019259921,DB0099910031282_,3.949729,0.945172328,NA,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,149754,DB00451,10063829,66,47205,14,15405,0.154121729,1.538422588,0.855091311,2.967247956,0.289684267,DB0045110063829_,1.238963682,0.430757598,NA,10063829,Device malfunction,10077536,Product issues,Prod,levothyroxine,DB00451
,149759,DB08911,10013709,31,1608,36,1712,0.805239013,0.916851168,0.545563251,1.532603108,0.894590507,DB0891110013709_,0.1113892,-0.086810123,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,trametinib,DB08911
,149790,DB00512,10003988,46,4691,24,5074,0.003717913,2.072989033,1.237171775,3.55669192,0.016077214,DB0051210003988_,4.130352283,0.728991543,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,vancomycin,DB00512
,149797,DB09153,10020772,125,7674,79,5620,0.318224135,1.158735089,0.865398279,1.559331832,0.486210446,DB0915310020772_,0.721113733,0.147328969,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,sodium chloride,DB09153
,149799,DB00512,10024378,40,4697,50,5048,0.52539635,0.859796575,0.551657363,1.332380855,0.683445577,DB0051210024378_,0.38060825,-0.151059459,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,vancomycin,DB00512
,149843,DB00650,10013710,36,2095,15,1999,0.0069064,2.289446766,1.218182687,4.515686159,0.026516904,DB0065010013710_,3.629972858,0.828310201,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,leucovorin,DB00650
,149844,DB00787,10013710,33,16967,83,17165,3.97489599521061e-06,0.402215565,0.26006458,0.609247012,4.83368684867503e-05,DB0078710013710_,9.937315966,-0.910767103,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,149855,DB00073,10024855,31,7375,19,6388,0.257630675,1.413185981,0.772659271,2.650434005,0.418478698,DB0007310024855_,0.871129291,0.345846716,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,rituximab,DB00073
,149858,DB08908,10050256,42,10631,16,3263,0.440861407,0.805709489,0.44286621,1.537306453,0.609127528,DB0890810050256_,0.495727628,-0.216032036,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,149862,DB00422,10042464,19,3416,32,2917,0.023158607,0.507075722,0.270940828,0.924493882,0.069275033,DB0042210042464_,2.669670718,-0.679094933,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,methylphenidate,DB00422
,149865,DB00364,10037087,47,2703,22,1378,0.798398876,1.089101656,0.64042212,1.905968533,0.891083795,DB0036410037087_,0.11531681,0.085353187,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,sucralfate,DB00364
,149866,DB01039,10037087,60,2913,52,2999,0.391331965,1.187875323,0.802627013,1.763050428,0.561226577,DB0103910037087_,0.577630575,0.172166268,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,fenofibrate,DB01039
,149868,DB00364,10047942,46,2704,24,1376,0.89930365,0.97533275,0.580323924,1.678150286,0.956490275,DB0036410047942_,0.044484657,-0.024976585,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,sucralfate,DB00364
,149869,DB00421,10047942,84,8819,40,5212,0.304378717,1.241105048,0.840557739,1.859690919,0.471024968,DB0042110047942_,0.752844177,0.216002151,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,spironolactone,DB00421
,149870,DB00678,10047942,193,15406,103,10621,0.037348963,1.291788052,1.010435311,1.659406558,0.100277577,DB0067810047942_,2.299813167,0.256027345,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,losartan,DB00678
,149880,DB00758,10001760,78,8222,16,10058,4.51850521085209e-14,5.962554935,3.448144066,10.9532843,2.4115514612639e-12,DB0075810001760_,26.75075082,1.78549907,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,clopidogrel,DB00758
,149885,DB00169,10003119,56,38635,41,18134,0.037736201,0.641084846,0.42073541,0.984196442,0.101077785,DB0016910003119_,2.291864912,-0.444593466,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,149900,DB00433,10005191,41,7615,19,6001,0.067219541,1.700462531,0.963678516,3.105518132,0.156394391,DB0043310005191_,1.855374317,0.530900291,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,prochlorperazine,DB00433
,149901,DB00451,10005191,221,47050,51,15368,0.023932814,1.415370177,1.039126679,1.960122147,0.07108181,DB0045110005191_,2.643923812,0.347391106,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,149905,DB06228,10005191,34,15878,27,16049,0.371619262,1.272808185,0.74503246,2.194409594,0.541254075,DB0622810005191_,0.61386647,0.241225629,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,rivaroxaban,DB06228
,149908,DB00794,10012735,40,796,19,590,0.138369816,1.559971084,0.872214088,2.882804768,0.267474576,DB0079410012735_,1.318730759,0.444667285,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,primidone,DB00794
,149913,DB01142,10016256,71,1669,27,757,0.504573499,1.192609364,0.748808032,1.949487709,0.665548334,DB0114210016256_,0.407144016,0.176143649,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,doxepin,DB01142
,149920,DB00904,10016766,92,22977,49,14407,0.386519126,1.177295849,0.823057384,1.701924599,0.556647686,DB0090410016766_,0.58582276,0.163220155,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,149921,DB01076,10016766,98,25649,81,25502,0.231257262,1.202936485,0.886593766,1.636054164,0.387443249,DB0107610016766_,0.948185895,0.184765638,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,atorvastatin,DB01076
,149933,DB00213,10021519,38,18857,23,13398,0.603994627,1.173848061,0.681273838,2.064922912,0.747439975,DB0021310021519_,0.291101278,0.160287293,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,149936,DB00695,10021519,54,27995,44,20484,0.609893749,0.898001177,0.591679807,1.369487224,0.75213743,DB0069510021519_,0.284836219,-0.1075839,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,149943,DB00231,10028334,49,3247,24,2115,0.279096597,1.329813442,0.797615127,2.27332325,0.442936008,DB0023110028334_,0.814329972,0.285038663,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,temazepam,DB00231
,149947,DB00794,10028813,37,799,23,586,0.594591679,1.179704931,0.67440399,2.10366753,0.740462148,DB0079410028813_,0.300480763,0.165264349,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,primidone,DB00794
,149951,DB01409,10030095,72,5959,46,3920,0.924749521,1.029643682,0.699829495,1.528222387,0.967593918,DB0140910030095_,0.032942786,0.029212803,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,149954,DB00497,10040844,53,19214,46,16329,0.919952704,0.979169732,0.646802991,1.487255026,0.964555064,DB0049710040844_,0.036088358,-0.021050278,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,oxycodone,DB00497
,149957,DB00904,10040844,82,22987,58,14398,0.487269317,0.885540526,0.624544802,1.262622716,0.651131245,DB0090410040844_,0.429044052,-0.121557057,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,149958,DB01076,10040844,70,25677,74,25509,0.738909531,0.939733213,0.667648161,1.321635506,0.849779265,DB0107610040844_,0.162778652,-0.06215926,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,149965,DB09140,10042674,85,3656,21,1777,0.004509039,1.96713632,1.204067405,3.351623609,0.018802945,DB0914010042674_,3.973741771,0.676578841,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,149970,DB00433,10047899,72,7584,63,5957,0.542962303,0.897687364,0.630050847,1.281774386,0.698141819,DB0043310047899_,0.359333018,-0.107933418,NA,10047899,Weight increased,10022891,Investigations,Inv,prochlorperazine,DB00433
,149974,DB01268,10047899,36,2107,53,3077,1,0.991950899,0.628558396,1.549525989,1,DB0126810047899_,0,-0.00808167,NA,10047899,Weight increased,10022891,Investigations,Inv,sunitinib,DB01268
,149975,DB00231,10048959,58,3238,25,2114,0.089758945,1.514552525,0.929162837,2.535397398,0.19483165,DB0023110048959_,1.635619427,0.415120032,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,149976,DB00268,10048959,73,2902,33,1512,0.535615734,1.152510172,0.75020794,1.804140878,0.692151661,DB0026810048959_,0.367950184,0.141942322,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,149979,DB01268,10048959,66,2077,77,3053,0.195285085,1.259852729,0.888446804,1.782462824,0.343395,DB0126810048959_,1.068873891,0.230994832,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,149982,DB00264,10049040,22,29585,38,24854,0.006384449,0.486378429,0.273924305,0.843817618,0.024883636,DB0026410049040_,3.693544891,-0.720768298,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,149996,DB00433,10053762,186,7470,126,5894,0.204443172,1.16473146,0.921501774,1.476083367,0.35446514,DB0043310053762_,1.037145274,0.152490554,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,prochlorperazine,DB00433
,149998,DB01142,10053762,41,1699,16,768,0.666994437,1.158253404,0.631385236,2.22548033,0.797649652,DB0114210053762_,0.226085811,0.146913184,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,doxepin,DB01142
,150006,DB00497,10061225,32,19235,37,16338,0.226828062,0.734618576,0.44280674,1.212621488,0.381994849,DB0049710061225_,0.962348154,-0.308403859,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,150079,DB00451,10064265,41,47230,13,15406,1,1.028767628,0.540260303,2.093174303,1,DB0045110064265_,0,0.028361608,NA,10064265,Skin haemorrhage,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,150140,DB01248,10016288,98,2602,54,1320,0.662140698,0.920680031,0.649224339,1.317345554,0.794021198,DB0124810016288_,0.23064512,-0.082642718,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,docetaxel,DB01248
,150143,DB00112,10042128,87,5846,43,4048,0.072914367,1.400935268,0.959107598,2.073411113,0.166389212,DB0011210042128_,1.793425585,0.337140062,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,150144,DB00222,10002855,34,3172,18,3110,0.036451896,1.851783569,1.01439449,3.490462363,0.098472569,DB0022210002855_,2.317977254,0.616149266,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,glimepiride,DB00222
,150206,DB00641,10060933,55,14069,36,12439,0.172100341,1.350755315,0.870856099,2.118499883,0.313598439,DB0064110060933_,1.15964197,0.300663928,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,150216,DB00437,10010264,97,6824,91,11455,7.68458499831265e-05,1.78917608,1.328024399,2.412567902,0.000636039,DB0043710010264_,7.360249902,0.581755223,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,150224,DB09072,10068319,41,6430,13,2522,0.548077576,1.236972122,0.648437886,2.520295079,0.702571035,DB0907210068319_,0.353008765,0.212666556,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium oxybate,DB09072
,150268,DB01373,10029216,83,22637,8,7373,0.000203275,3.379206222,1.636489438,8.090259624,0.001461059,DB0137310029216_,6.52859391,1.217640836,female,10029216,Nervousness,10037175,Psychiatric disorders,Psych,calcium,DB01373
,150273,DB06643,10040753,126,52295,20,7495,0.618206484,0.902955341,0.560167829,1.529484498,0.759105174,DB0664310040753_,0.275614941,-0.102082183,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,denosumab,DB06643
,150293,DB01609,10054112,71,1513,55,1288,0.648171017,1.098870909,0.755532558,1.6054268,0.783192369,DB0160910054112_,0.244376932,0.094283206,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,deferasirox,DB01609
,150305,DB01181,10037660,30,543,62,858,0.269049706,0.76470331,0.470812436,1.218676235,0.431565035,DB0118110037660_,0.84033706,-0.26826735,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ifosfamide,DB01181
,150306,DB01181,10047700,28,545,55,865,0.416970697,0.808126371,0.48714112,1.31453376,0.586100254,DB0118110047700_,0.534264421,-0.213036832,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ifosfamide,DB01181
,150316,DB01104,10031009,43,15420,10,7276,0.039510675,2.028920572,1.003225281,4.530852534,0.104680788,DB0110410031009_,2.256839677,0.707503914,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,150336,DB06724,10017944,39,7890,14,3905,0.379987956,1.378715816,0.731249813,2.752648874,0.550119581,DB0672410017944_,0.597619604,0.321152498,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,150355,DB00999,10044034,70,21360,18,12221,0.001732461,2.224955687,1.309951829,3.971654841,0.008637657,DB0099910044034_,4.75162386,0.799737,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,150356,DB06724,10044034,62,7867,8,3911,5.49013217601579e-05,3.85226262,1.836147946,9.325393995,0.000478317,DB0672410044034_,7.64523766,1.348660669,female,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,150364,DB00999,10049848,137,21293,95,12144,0.150512052,0.822488444,0.627847192,1.081115113,0.284660331,DB0099910049848_,1.25645863,-0.195420847,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,150365,DB06724,10049848,62,7867,18,3901,0.043185298,1.707922734,0.995617056,3.072441623,0.112039239,DB0672410049848_,2.188906125,0.535277857,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,150381,DB06724,10061024,32,7897,24,3895,0.119811628,0.657642828,0.37478176,1.168577829,0.241118492,DB0672410061024_,1.422466796,-0.41909331,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,calcium carbonate,DB06724
,150386,DB06724,10061623,68,7861,29,3890,0.588098844,1.160306968,0.739621914,1.862599409,0.735071119,DB0672410061623_,0.307788023,0.148684598,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,150389,DB06724,10061822,54,7875,31,3888,0.490219262,0.860038454,0.542064379,1.386445938,0.653503053,DB0672410061822_,0.425408074,-0.150778177,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,150392,DB00999,10062244,66,21364,11,12228,2.40057173951313e-05,3.434081862,1.799177663,7.214360285,0.000233139,DB0099910062244_,8.363876384,1.233749601,female,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,150396,DB00916,10008479,46,5277,23,2408,0.697915041,0.912653863,0.540538979,1.581344633,0.818265616,DB0091610008479_,0.200568281,-0.09139859,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,150428,DB00019,10003239,151,18861,61,9468,0.165017331,1.242580715,0.916148139,1.703440312,0.304160482,DB0001910003239_,1.190199815,0.217190439,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pegfilgrastim,DB00019
,150430,DB00193,10074903,137,19183,62,8640,1,0.995236182,0.731233806,1.367637768,1,DB0019310074903_,0,-0.004775201,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,150431,DB00482,10074903,96,8163,18,3053,0.005648073,1.994616807,1.19481792,3.514201822,0.022560535,DB0048210074903_,3.791553139,0.690451955,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,celecoxib,DB00482
,150452,DB00641,10057362,46,14078,46,12429,0.601189682,0.882871856,0.573317562,1.359556573,0.745442875,DB0064110057362_,0.293776774,-0.124575212,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,150477,DB00331,10015958,61,24885,35,20717,0.081619447,1.450930648,0.941886135,2.266774559,0.181060596,DB0033110015958_,1.708923518,0.372205177,NA,10015958,Eye pain,10015919,Eye disorders,Eye,metformin,DB00331
,150568,DB08820,10010264,56,4345,43,3502,0.839382514,1.049656955,0.691002196,1.604282747,0.917718939,DB0882010010264_,0.085864101,0.048463402,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ivacaftor,DB08820
,150578,DB00343,10002855,115,8621,24,5071,5.21277571782216e-07,2.818340134,1.80057697,4.583169264,8.04227666063311e-06,DB0034310002855_,11.73079835,1.036148107,female,10002855,Anxiety,10037175,Psychiatric disorders,Psych,diltiazem,DB00343
,150579,DB00394,10002855,45,1594,9,785,0.01188933,2.461602961,1.180604458,5.758139753,0.040867141,DB0039410002855_,3.197428928,0.900812748,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,beclomethasone dipropionate,DB00394
,150580,DB00852,10002855,43,1123,10,461,0.123103586,1.764643015,0.863889993,3.972847008,0.245834847,DB0085210002855_,1.403095321,0.567948412,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,pseudoephedrine,DB00852
,150585,DB00695,10002948,46,28003,17,20511,0.01493647,1.981903647,1.114394583,3.688639118,0.049147754,DB0069510002948_,3.012924137,0.684057821,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,150587,DB00761,10002948,36,15271,18,8607,0.777066097,1.127246498,0.62313681,2.109945719,0.878512755,DB0076110002948_,0.129524852,0.119777931,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,150592,DB01050,10002948,35,18073,25,9346,0.221702709,0.723954416,0.42083904,1.262727465,0.375625609,DB0105010002948_,0.979162352,-0.32302685,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,150594,DB00394,10003239,47,1592,14,780,0.127460364,1.644525107,0.883556771,3.254941024,0.252030858,DB0039410003239_,1.378203747,0.497451654,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,beclomethasone dipropionate,DB00394
,150597,DB01233,10003239,64,3357,22,1704,0.134065057,1.476538749,0.893606476,2.526960538,0.261416915,DB0123310003239_,1.341638771,0.389700666,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,metoclopramide,DB01233
,150601,DB00455,10007515,33,9368,34,5084,0.009985445,0.526743668,0.315819605,0.877692422,0.035524498,DB0045510007515_,3.337532727,-0.641041248,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,loratadine,DB00455
,150638,DB00394,10011224,85,1554,32,762,0.226467138,1.302376647,0.849150478,2.041013044,0.381474549,DB0039410011224_,0.963711144,0.264190785,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,beclomethasone dipropionate,DB00394
,150641,DB01233,10011224,88,3333,29,1697,0.047239842,1.544888683,1.000567749,2.449027946,0.119901433,DB0123310011224_,2.121085268,0.434951858,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoclopramide,DB01233
,150652,DB00852,10013968,59,1107,26,445,0.712688954,0.912258241,0.557754241,1.528420813,0.829206966,DB0085210013968_,0.187285498,-0.09183217,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pseudoephedrine,DB00852
,150653,DB00993,10016173,60,3189,16,1603,0.026475796,1.884777757,1.067593485,3.517488202,0.076807715,DB0099310016173_,2.566450185,0.633809913,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,azathioprine,DB00993
,150658,DB00656,10018100,43,11970,14,6605,0.096063635,1.694757878,0.908650013,3.356615761,0.204861351,DB0065610018100_,1.585421865,0.527539886,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,150663,DB00996,10018100,94,38859,41,22384,0.152247523,1.320651275,0.905555326,1.956181535,0.287085344,DB0099610018100_,1.247975741,0.278125005,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,150664,DB01050,10018100,52,18056,15,9356,0.052028199,1.796272781,0.995231526,3.437381901,0.128852841,DB0105010018100_,2.049084292,0.585713841,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,150669,DB01233,10020937,38,3383,13,1713,0.237259481,1.480010471,0.768740988,3.03631973,0.394611792,DB0123310020937_,0.929852802,0.392049162,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,metoclopramide,DB01233
,150674,DB00695,10021688,43,28006,26,20502,0.466753615,1.210703142,0.726965039,2.053136909,0.633382486,DB0069510021688_,0.456680796,0.1912013,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,furosemide,DB00695
,150680,DB00343,10022437,111,8625,50,5045,0.139070376,1.29851543,0.920126744,1.854829454,0.268527498,DB0034310022437_,1.314801959,0.261221635,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,diltiazem,DB00343
,150688,DB00343,10028836,49,8687,10,5085,0.001061181,2.868059603,1.433603736,6.356204172,0.005786959,DB0034310028836_,5.152148309,1.053635705,female,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,diltiazem,DB00343
,150689,DB00656,10028836,74,11939,25,6594,0.034890163,1.634790069,1.025345515,2.688610689,0.095207675,DB0065610028836_,2.351694726,0.491514398,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,150695,DB00338,10029216,134,33540,39,22233,1.7022378246929e-06,2.277546676,1.583114716,3.344166518,2.30101934800992e-05,DB0033810029216_,10.67957325,0.823098844,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,150696,DB00343,10029216,45,8691,13,5082,0.028102803,2.024015264,1.071719627,4.094079869,0.080462086,DB0034310029216_,2.51996919,0.705083293,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,diltiazem,DB00343
,150698,DB00656,10029216,51,11962,18,6601,0.129695074,1.563485364,0.897176226,2.846124258,0.255234157,DB0065610029216_,1.365573893,0.446917537,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,150700,DB00761,10029216,48,15259,7,8618,0.000188353,3.872616305,1.741210255,10.14931131,0.0013711,DB0076110029216_,6.592141936,1.353930326,female,10029216,Nervousness,10037175,Psychiatric disorders,Psych,potassium chloride,DB00761
,150725,DB00115,10046555,30,18395,41,10431,0.000275253,0.414929339,0.24999401,0.681400427,0.00188118,DB0011510046555_,6.275855934,-0.879647042,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,cyanocobalamin,DB00115
,150728,DB00656,10046555,25,11988,32,6587,0.001985195,0.429286797,0.243673478,0.748379295,0.009666703,DB0065610046555_,4.639068008,-0.845630059,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,trazodone,DB00656
,150746,DB00455,10048393,48,9353,12,5106,0.014158604,2.183580685,1.141361152,4.520297741,0.047022414,DB0045510048393_,3.057130901,0.780966045,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,150748,DB00761,10048393,42,15265,12,8613,0.033759189,1.974759715,1.019992202,4.122704312,0.092902714,DB0076110048393_,2.376202417,0.680446728,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,150823,DB00563,10062556,92,46554,34,15314,0.537076242,0.890091353,0.594375657,1.361503514,0.693252585,DB0056310062556_,0.366360866,-0.116431177,NA,10062556,Grip strength decreased,10022891,Investigations,Inv,methotrexate,DB00563
,150848,DB00230,10013952,102,19572,39,8612,0.521199627,1.150799809,0.787703376,1.711573561,0.680064167,DB0023010013952_,0.385568122,0.140457187,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,150884,DB00973,10030124,41,3810,38,2983,0.494566295,0.84477416,0.528456722,1.353386209,0.657063614,DB0097310030124_,0.41997444,-0.168685954,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,150886,DB00230,10031161,110,19564,22,8629,0.000407997,2.205274323,1.384911204,3.664565623,0.002605806,DB0023010031161_,5.950013317,0.790851911,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,150926,DB01261,10048959,72,3709,43,3260,0.047913209,1.471635808,0.99178984,2.206670367,0.121199181,DB0126110048959_,2.110319964,0.386374576,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,150968,DB01240,10043554,48,5703,16,1560,0.540428252,0.820644134,0.456380677,1.552690093,0.695972984,DB0124010043554_,0.362444435,-0.197665718,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,epoprostenol,DB01240
,150970,DB08880,10000059,76,3262,15,794,0.506729153,1.2332108,0.698091289,2.323578885,0.667420429,DB0888010000059_,0.404335104,0.209621175,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,teriflunomide,DB08880
,150978,DB08880,10061428,41,3297,14,795,0.302123487,0.706227464,0.37493455,1.409831577,0.468445118,DB0888010061428_,0.758336329,-0.347817906,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,teriflunomide,DB08880
,150991,DB08877,10040047,37,3252,58,3171,0.029459134,0.622090599,0.399159218,0.958788824,0.08351759,DB0887710040047_,2.482698014,-0.474669539,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ruxolitinib,DB08877
,151001,DB00480,10002368,17,67411,34,67628,0.0240772,0.501614802,0.262778151,0.923264916,0.071421873,DB0048010002368_,2.639151119,-0.68992278,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,151023,DB01073,10012735,33,1032,46,1604,0.641600674,1.114967695,0.685697711,1.795374153,0.77822264,DB0107310012735_,0.250742626,0.108825431,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fludarabine,DB01073
,151033,DB00987,10054236,14,2090,37,2891,0.044865911,0.52345851,0.260706425,0.994365435,0.115329369,DB0098710054236_,2.159963165,-0.647297507,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,cytarabine,DB00987
,151034,DB01015,10054236,58,9829,52,9329,0.775130451,1.05866255,0.714620461,1.571782727,0.877413689,DB0101510054236_,0.130776688,0.057006366,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,151064,DB01202,10066901,39,6675,24,5694,0.253939542,1.386141313,0.811789225,2.412720282,0.414506668,DB0120210066901_,0.880666218,0.326523853,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,151066,DB09035,10021097,101,4625,152,6538,0.651808474,0.939309304,0.720915182,1.219671314,0.786166625,DB0903510021097_,0.240586517,-0.062610457,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,nivolumab,DB09035
,151071,DB00476,10022061,134,17123,11,6166,1.24902845885091e-08,4.386634611,2.372310813,9.004564112,2.75194577040202e-07,DB0047610022061_,15.10578744,1.47856233,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,151072,DB00335,10035226,56,8410,48,5417,0.158388317,0.75149569,0.501093994,1.130778716,0.295327865,DB0033510035226_,1.219669132,-0.285689805,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,atenolol,DB00335
,151077,DB00480,10061275,32,67396,67,67595,0.000560671,0.479027192,0.304117382,0.740465497,0.003392939,DB0048010061275_,5.686058912,-0.735997914,NA,10061275,Mantle cell lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,151088,DB00087,10010264,46,1323,26,721,0.900480286,0.964228366,0.578074012,1.639508642,0.956698706,DB0008710010264_,0.044266769,-0.036427118,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,alemtuzumab,DB00087
,151089,DB00877,10010264,34,1074,29,1402,0.096326,1.530183542,0.898547599,2.621527129,0.205213885,DB0087710010264_,1.5837025,0.42538769,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,sirolimus,DB00877
,151090,DB00087,10016256,89,1280,36,711,0.123396915,1.373045363,0.911494518,2.105756316,0.246250457,DB0008710016256_,1.401406141,0.317031165,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,alemtuzumab,DB00087
,151097,DB08889,10028813,151,3014,117,3768,0.000129792,1.613325358,1.252617773,2.082013157,0.000996083,DB0888910028813_,6.911679686,0.478297488,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,carfilzomib,DB08889
,151098,DB00480,10033645,68,67360,57,67605,0.326150961,1.197318323,0.829491526,1.733760011,0.494684248,DB0048010033645_,0.703835603,0.180084325,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,151100,DB08889,10047700,59,3106,47,3838,0.029997646,1.55104489,1.036158451,2.333367841,0.084698976,DB0888910047700_,2.468651771,0.438928827,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,carfilzomib,DB08889
,151114,DB00316,10061126,37,65437,16,36937,0.395181679,1.305336278,0.708360558,2.513490621,0.564978732,DB0031610061126_,0.570967192,0.266460692,NA,10061126,Escherichia infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,151144,DB08904,10006451,116,11494,24,3535,0.087917617,1.486436941,0.949781385,2.417285147,0.191713503,DB0890410006451_,1.651753195,0.396381941,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,151146,DB00065,10016322,54,9410,26,4931,0.813611865,1.088333894,0.668848824,1.813014935,0.899904811,DB0006510016322_,0.105466287,0.084647989,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,151153,DB06273,10052904,64,5031,11,1399,0.15905044,1.617761918,0.843434652,3.411566904,0.296236727,DB0627310052904_,1.216596392,0.481043662,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,tocilizumab,DB06273
,151159,DB00051,10043071,32,25699,29,11391,0.007659049,0.489095207,0.28645044,0.838429421,0.028765893,DB0005110043071_,3.54856488,-0.715198111,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,adalimumab,DB00051
,151168,DB06228,10010305,86,15826,84,15992,0.877827432,1.034556096,0.756265832,1.415652129,0.948266477,DB0622810010305_,0.053119722,0.033972441,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,rivaroxaban,DB06228
,151170,DB00213,10013082,40,18855,17,13404,0.080530961,1.672674083,0.926550162,3.148081861,0.179287367,DB0021310013082_,1.718765357,0.514423593,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,151199,DB00203,10001551,81,13797,59,8879,0.487755023,0.883519257,0.623233709,1.258856181,0.651472708,DB0020310001551_,0.428519775,-0.123842191,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,sildenafil,DB00203
,151200,DB00203,10003481,89,13789,57,8881,1,1.005643786,0.712355832,1.429632904,1,DB0020310003481_,0,0.00562792,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,sildenafil,DB00203
,151202,DB00563,10047482,38,46608,12,15336,1,1.041991833,0.532838167,2.190812328,1,DB0056310047482_,0,0.041134105,NA,10047482,Viral upper respiratory tract infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,151216,DB00287,10011906,43,1358,37,780,0.077727586,0.667670458,0.416150046,1.075636338,0.174502015,DB0028710011906_,1.745818989,-0.403960553,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,travoprost,DB00287
,151295,DB00497,10042609,87,19180,59,16316,0.184072288,1.254380057,0.890417266,1.777908576,0.329027683,DB0049710042609_,1.111613389,0.226641472,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,oxycodone,DB00497
,151308,DB00335,10052904,46,8420,20,5445,0.164243188,1.487310454,0.861296095,2.65745555,0.303082134,DB0033510052904_,1.193751439,0.396969425,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,151316,DB00331,10020646,57,24889,129,20623,5.96120177059781e-11,0.366132062,0.263068212,0.504107916,2.0179032651663e-09,DB0033110020646_,20.02120685,-1.004761187,male,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,151336,DB00390,10000087,73,4072,35,3266,0.014357463,1.672759662,1.10017223,2.586722516,0.047560944,DB0039010000087_,3.045743367,0.514474755,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,digoxin,DB00390
,151337,DB00727,10000087,47,3796,47,4126,0.755602168,1.086909857,0.707971574,1.668716017,0.862925027,DB0072710000087_,0.147427467,0.083338677,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,nitroglycerin,DB00727
,151338,DB01222,10000087,106,9168,33,5372,0.001046824,1.882070543,1.260665898,2.877114072,0.005725293,DB0122210000087_,5.162861494,0.632372523,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,budesonide,DB01222
,151339,DB00316,10003119,89,65385,59,36894,0.346685242,0.851176967,0.605542054,1.204061881,0.516105773,DB0031610003119_,0.661443548,-0.16113522,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,151344,DB00982,10013774,36,3328,25,2076,0.692797145,0.898289021,0.522832125,1.566007422,0.814936921,DB0098210013774_,0.204644567,-0.107263413,NA,10013774,Dry eye,10015919,Eye disorders,Eye,isotretinoin,DB00982
,151354,DB00715,10028372,40,4803,16,2271,0.667027431,1.182032487,0.645726248,2.266130542,0.797649652,DB0071510028372_,0.226085811,0.167235404,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,paroxetine,DB00715
,151355,DB01104,10006002,52,15411,17,7269,0.19905582,1.442762964,0.820231449,2.663092628,0.347896022,DB0110410006002_,1.05585163,0.36656,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,151356,DB01104,10019303,70,15393,38,7248,0.471147119,0.867394249,0.575686623,1.324919647,0.637417926,DB0110410019303_,0.450329754,-0.142261678,NA,10019303,Heart rate increased,10022891,Investigations,Inv,sertraline,DB01104
,151362,DB08889,10012735,131,3034,140,3745,0.262345776,1.154967397,0.898591901,1.483721144,0.424080362,DB0888910012735_,0.857832308,0.144072116,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,carfilzomib,DB08889
,151364,DB08889,10033371,70,3095,60,3825,0.040736055,1.441749417,1.003108735,2.077704275,0.107106853,DB0888910033371_,2.233928314,0.365857249,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,151366,DB01234,10036018,58,31567,94,32794,0.00733013,0.64101215,0.453758702,0.898946632,0.027774609,DB0123410036018_,3.583633023,-0.444706867,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,dexamethasone,DB01234
,151385,DB00451,10050031,49,47222,9,15410,0.126946514,1.776601082,0.86336768,4.114891655,0.251396754,DB0045110050031_,1.380722896,0.574702035,NA,10050031,Muscle strain,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,151388,DB00829,10050584,71,7981,16,4438,0.000655291,2.46740976,1.417775419,4.553975234,0.003877603,DB0082910050584_,5.552538037,0.90316892,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,151389,DB00451,10060820,82,47189,20,15399,0.299852526,1.337915814,0.812538903,2.304518705,0.465885836,DB0045110060820_,0.763814661,0.29111304,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,151390,DB00682,10060820,38,19421,12,16352,0.002488527,2.666097978,1.363346437,5.606349208,0.011622414,DB0068210060820_,4.454819835,0.980615972,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,151407,DB00158,10005483,55,16760,41,8063,0.037793139,0.64535997,0.422514282,0.992800942,0.101216839,DB0015810005483_,2.290490139,-0.437947025,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,folic acid,DB00158
,151409,DB00158,10012174,179,16636,99,8005,0.27404445,0.870034852,0.675862365,1.125358011,0.43714911,DB0015810012174_,0.827480929,-0.139222008,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,folic acid,DB00158
,151441,DB00328,10018627,10,750,40,775,3.81149909663162e-05,0.258550316,0.114431136,0.530839302,0.000350237,DB0032810018627_,7.95690089,-1.352664956,male,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,indomethacin,DB00328
,151448,DB00480,10016952,46,67382,25,67637,0.012607549,1.846943662,1.111185642,3.137144068,0.042831773,DB0048010016952_,3.15047509,0.613532198,NA,10016952,Food poisoning,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,151450,DB06403,10036653,145,21326,28,6633,0.01946257,1.610616865,1.067971633,2.510546223,0.060523355,DB0640310036653_,2.804725957,0.476617251,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,151455,DB00820,10017885,113,11802,51,5765,0.676746381,1.082304117,0.76975285,1.539928552,0.803963008,DB0082010017885_,0.218202021,0.07909221,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,151456,DB01240,10017885,67,5684,16,1560,0.688450669,1.14925652,0.656508689,2.131098735,0.812186703,DB0124010017885_,0.208025035,0.139115229,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,151457,DB08932,10017885,248,19195,62,6535,0.030075809,1.361774531,1.025634905,1.83178117,0.084863146,DB0893210017885_,2.466715364,0.308788651,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,151464,DB00795,10012735,181,4388,66,1437,0.452578674,0.898126035,0.66937872,1.217145886,0.620198658,DB0079510012735_,0.477715437,-0.10744487,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sulfasalazine,DB00795
,151465,DB01296,10012735,105,1344,60,923,0.286287331,1.201732065,0.856676584,1.698279852,0.451034674,DB0129610012735_,0.796211059,0.183763903,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,glucosamine,DB01296
,151482,DB05676,10044565,245,46884,101,25228,0.023817678,1.305295852,1.030598065,1.663381419,0.070819872,DB0567610044565_,2.647615643,0.266429722,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,151493,DB00635,10010144,42,33011,89,23705,2.16500924092236e-09,0.338881664,0.22892065,0.49459762,5.61769673224524e-08,DB0063510010144_,16.694759,-1.082104306,male,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,151499,DB00836,10008190,30,5505,38,4037,0.026592737,0.578993536,0.345783603,0.96144689,0.077070411,DB0083610008190_,2.563035851,-0.546463965,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,151500,DB00455,10047571,70,9331,24,5094,0.05113405,1.59222548,0.987511218,2.651276765,0.127163867,DB0045510047571_,2.062278731,0.46513271,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,loratadine,DB00455
,151562,DB00586,10016825,38,7071,12,2793,0.636792473,1.250769921,0.638679754,2.633204287,0.774232199,DB0058610016825_,0.255883452,0.223759299,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,diclofenac,DB00586
,151563,DB00814,10016825,44,8243,10,3405,0.098412089,1.817461435,0.899832953,4.054988092,0.208508928,DB0081410016825_,1.567773416,0.597440712,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,meloxicam,DB00814
,151564,DB00814,10033775,128,8159,47,3368,0.557643069,1.124195155,0.79677236,1.609871218,0.710708304,DB0081410033775_,0.341493195,0.117067362,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,151565,DB00115,10073085,52,18373,28,10444,0.907409384,1.055681753,0.654095101,1.737172535,0.958745315,DB0011510073085_,0.042129813,0.054186769,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,151566,DB00404,10073085,42,19850,15,9847,0.324818976,1.38899623,0.754197867,2.697940656,0.493261701,DB0040410073085_,0.706715412,0.32858135,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,151579,DB00264,10016338,41,29566,19,24873,0.037164611,1.815348982,1.029735084,3.312423838,0.09989461,DB0026410016338_,2.303639551,0.596277726,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,151597,DB00656,10020642,124,11889,83,6536,0.166149105,0.821336436,0.615947985,1.099891799,0.305625055,DB0065610020642_,1.185396237,-0.196822465,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,trazodone,DB00656
,151598,DB00814,10020642,91,8196,36,3379,0.921867999,1.042111798,0.6996188,1.58203119,0.965486617,DB0081410020642_,0.035123039,0.04124923,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,meloxicam,DB00814
,151600,DB01261,10020642,32,3749,23,3280,0.500193073,1.217217541,0.68878327,2.183197829,0.661779581,DB0126110020642_,0.412822738,0.19656755,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,sitagliptin,DB01261
,151601,DB00264,10022998,49,29558,42,24850,1,0.980836125,0.635988761,1.518603283,1,DB0026410022998_,0,-0.019349882,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,151602,DB00695,10022998,49,28000,29,20499,0.422276697,1.237002736,0.765776201,2.031612064,0.591327271,DB0069510022998_,0.525385657,0.212691305,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,151604,DB00814,10022998,37,8250,18,3397,0.554315207,0.846420853,0.469081823,1.58168605,0.707857031,DB0081410022998_,0.345513139,-0.166738581,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,meloxicam,DB00814
,151613,DB00982,10018836,35,3329,22,2079,1,0.993541874,0.564911121,1.783135332,1,DB0098210018836_,0,-0.00647907,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,isotretinoin,DB00982
,151620,DB00661,10002855,47,3481,18,1577,0.592275808,1.182863121,0.671609747,2.171421782,0.738465935,DB0066110002855_,0.303180305,0.167937873,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,verapamil,DB00661
,151667,DB00374,10047461,123,17593,30,5694,0.186160835,1.32694161,0.883188058,2.051908664,0.331632501,DB0037410047461_,1.103727846,0.282876753,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,151673,DB00398,10012174,21,706,46,1492,1,0.964788028,0.542486692,1.66444406,1,DB0039810012174_,0,-0.035846862,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,sorafenib,DB00398
,151678,DB00904,10019063,90,22979,62,14394,0.560082637,0.909291192,0.650236978,1.278574281,0.712728916,DB0090410019063_,0.338654133,-0.095089893,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,151709,DB00213,10037400,116,18779,48,13373,0.001416367,1.720936783,1.218325737,2.464028071,0.007329307,DB0021310037400_,4.91587429,0.542868784,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,151742,DB00316,10062060,85,65389,43,36910,0.581954895,1.115822601,0.764255457,1.650310676,0.730169427,DB0031610062060_,0.31447868,0.109591892,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,151757,DB00586,10010264,177,6932,55,2750,0.12176484,1.276633043,0.935090834,1.766734256,0.243945009,DB0058610010264_,1.410812452,0.244226177,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,151759,DB01026,10013573,38,1072,29,1039,0.38543764,1.269866216,0.756422354,2.152110449,0.555592502,DB0102610013573_,0.587720163,0.238911554,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ketoconazole,DB01026
,151764,DB01026,10019211,75,1035,48,1020,0.025590323,1.539544099,1.045842899,2.28450571,0.074808613,DB0102610019211_,2.592822247,0.431486333,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ketoconazole,DB01026
,151766,DB00186,10028116,58,16843,31,9977,0.741909808,1.108284665,0.704207452,1.774951319,0.852093841,DB0018610028116_,0.160058616,0.102813473,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,151771,DB00620,10028411,43,4785,24,3108,0.616326643,1.163678628,0.688941719,2.009263482,0.757494018,DB0062010028411_,0.277739638,0.151586218,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,triamcinolone,DB00620
,151773,DB01026,10028813,86,1024,47,1021,0.001213717,1.823920819,1.249351546,2.690362111,0.006459666,DB0102610028813_,5.042177622,0.60098848,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ketoconazole,DB01026
,151779,DB00193,10042128,98,19222,38,8664,0.458729418,1.162403212,0.79094862,1.739724492,0.626113965,DB0019310042128_,0.468222871,0.150489596,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,151782,DB00193,10042682,65,19255,18,8684,0.074227008,1.62858449,0.953674518,2.919358202,0.168565113,DB0019310042682_,1.780433175,0.487711227,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,151788,DB00586,10044565,85,7024,28,2777,0.462468488,1.200165117,0.772882208,1.915739486,0.62969692,DB0058610044565_,0.462516654,0.182459145,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,151791,DB00586,10048439,43,7066,12,2793,0.367416126,1.416296342,0.732370026,2.955117862,0.537096539,DB0058610048439_,0.621577426,0.348045254,NA,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,151797,DB00193,10050256,36,19284,16,8686,1,1.013461649,0.547909236,1.957149474,1,DB0019310050256_,0,0.013371846,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,151800,DB01026,10053762,47,1063,49,1019,0.754305847,0.9195288,0.597046337,1.414796013,0.861890505,DB0102610053762_,0.148627041,-0.083893914,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ketoconazole,DB01026
,151801,DB00186,10057362,49,16852,26,9982,0.720273603,1.116333508,0.679851811,1.872559403,0.83489187,DB0018610057362_,0.180453059,0.110049661,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,151802,DB00193,10057362,42,19278,15,8687,0.477399933,1.261689419,0.685057676,2.450719745,0.642759952,DB0019310057362_,0.441983949,0.232451632,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,151809,DB00193,10064355,80,19240,31,8671,0.537798933,1.163019102,0.758798808,1.823610045,0.693928509,DB0019310064355_,0.365386337,0.151019298,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,151813,DB00586,10074903,80,7029,22,2783,0.150601163,1.439638022,0.886825746,2.429528437,0.284757154,DB0058610074903_,1.256118555,0.364391709,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,diclofenac,DB00586
,151816,DB00820,10022086,46,11869,20,5796,0.792913567,1.123148478,0.650556169,2.006272162,0.88777003,DB0082010022086_,0.119042545,0.116135882,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,151817,DB00108,10010774,37,10157,16,3279,0.337169685,0.746565464,0.404586914,1.439428896,0.506327601,DB0010810010774_,0.680571387,-0.292271971,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,natalizumab,DB00108
,151832,DB00264,10014418,40,29567,25,24867,0.263723472,1.345653026,0.796334001,2.315176322,0.425574574,DB0026410014418_,0.854315084,0.296879416,NA,10014418,Electrolyte imbalance,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,151843,DB14500,10043554,54,7755,26,4047,0.813530177,1.083846908,0.665884415,1.806053447,0.899871258,DB1450010043554_,0.105503572,0.080516664,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,potassium,DB14500
,151844,DB14513,10043554,52,7125,19,3545,0.311472394,1.36168258,0.790175079,2.442780588,0.478971033,DB1451310043554_,0.736115157,0.308721126,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,magnesium,DB14513
,151847,DB00635,10002424,54,32999,30,23764,0.270048293,1.296250894,0.814517472,2.098942537,0.432700302,DB0063510002424_,0.837709935,0.25947617,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,151854,DB00814,10040753,156,8131,48,3367,0.074297891,1.345727423,0.965441985,1.905658195,0.168682364,DB0081410040753_,1.779737836,0.296934702,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,meloxicam,DB00814
,151855,DB01097,10040753,141,6124,16,1487,0.00213829,2.13959398,1.267740886,3.858211321,0.010278577,DB0109710040753_,4.577693475,0.760616082,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,leflunomide,DB01097
,151862,DB01611,10011906,136,11777,53,2308,6.67803693859964e-05,0.502890351,0.362367661,0.706746214,0.000563959,DB0161110011906_,7.48052922,-0.687383122,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,151868,DB08934,10013710,20,4469,57,6147,0.005073968,0.482656818,0.274244863,0.817104639,0.020699866,DB0893410013710_,3.877628037,-0.728449399,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,sofosbuvir,DB08934
,151884,DB00399,10028810,144,6848,66,4932,0.002340013,1.571309364,1.163378611,2.140996131,0.011055888,DB0039910028810_,4.504792105,0.451909262,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,zoledronic acid,DB00399
,151886,DB14513,10028810,166,7011,58,3506,0.02152095,1.431193693,1.052190819,1.970394514,0.065507444,DB1451310028810_,2.725591487,0.358508846,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,magnesium,DB14513
,151887,DB00213,10039073,109,18786,21,13400,5.74874167841332e-10,3.702195383,2.304205291,6.223381532,1.6669131276017e-08,DB0021310039073_,17.90970725,1.30892599,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,151918,DB00043,10028372,38,6375,13,2287,1,1.048608945,0.545222128,2.149395723,1,DB0004310028372_,0,0.047464471,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,omalizumab,DB00043
,151919,DB00471,10028372,99,14090,35,5430,0.699852398,1.090068295,0.733554477,1.654118401,0.819622255,DB0047110028372_,0.19891171,0.08624035,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,151924,DB14512,10028411,39,4805,24,2388,0.421840465,0.807638926,0.472372138,1.40741242,0.590908918,DB1451210028411_,0.526093389,-0.213640194,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,mometasone furoate,DB14512
,151926,DB00471,10029331,126,14063,60,5405,0.188063199,0.807101444,0.587935864,1.118639299,0.334115659,DB0047110029331_,1.096268062,-0.214305914,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,151966,DB00668,10069327,43,10048,22,4281,0.498140166,0.832774737,0.486572242,1.463706649,0.66013987,DB0066810069327_,0.415303542,-0.182992098,NA,10069327,Product quality issue,10077536,Product issues,Prod,epinephrine,DB00668
,151979,DB09053,10007515,8,2277,47,4005,0.00058572,0.299431533,0.122014471,0.641054234,0.003524647,DB0905310007515_,5.647975087,-1.205869492,male,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,ibrutinib,DB09053
,152006,DB00973,10047895,101,3750,69,2952,0.39006208,1.152243424,0.836647881,1.594800385,0.559985896,DB0097310047895_,0.57984368,0.141710845,NA,10047895,Weight decreased,10022891,Investigations,Inv,ezetimibe,DB00973
,152029,DB00813,10035669,27,10545,41,10127,0.068558526,0.632450648,0.37380788,1.054042704,0.158708958,DB0081310035669_,1.84068321,-0.458153088,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,fentanyl,DB00813
,152032,DB11089,10035669,40,10135,43,8364,0.268996149,0.767698661,0.485893742,1.210496243,0.431526627,DB1108910035669_,0.840426062,-0.264357992,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,docusate,DB11089
,152073,DB00390,10016825,57,4088,15,3286,3.81396333956606e-05,3.053999021,1.70228331,5.819568049,0.000350402,DB0039010016825_,7.95642935,1.116451886,female,10016825,Flushing,10047065,Vascular disorders,Vasc,digoxin,DB00390
,152091,DB00695,10030041,45,28004,29,20499,0.638721775,1.135828021,0.696495949,1.879370055,0.77585849,DB0069510030041_,0.253785133,0.127361919,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,furosemide,DB00695
,152092,DB00524,10033318,49,1528,23,1321,0.016430284,1.841448703,1.093914426,3.185229055,0.052912279,DB0052410033318_,2.939119844,0.6105526,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,metolazone,DB00524
,152093,DB00203,10037844,279,13599,175,8763,0.808248133,1.027335303,0.845680894,1.250701281,0.896499722,DB0020310037844_,0.109257296,0.026968365,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sildenafil,DB00203
,152100,DB00203,10038776,60,13818,12,8926,4.96964141126684e-05,3.229688483,1.718583644,6.598567098,0.000439452,DB0020310038776_,7.729982693,1.172385688,female,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,152101,DB00374,10038776,81,17635,14,5710,0.030462809,1.873210987,1.053691902,3.581256888,0.085685312,DB0037410038776_,2.457073851,0.627654064,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,152111,DB00374,10041349,145,17571,48,5676,0.866637023,0.975826555,0.698559938,1.384239889,0.93980874,DB0037410041349_,0.062078892,-0.024470418,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,152112,DB00390,10041349,49,4096,37,3264,0.828058453,1.055325049,0.672834564,1.667904074,0.909617051,DB0039010041349_,0.094731591,0.053848822,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,digoxin,DB00390
,152113,DB00421,10041349,88,8815,46,5206,0.530529585,1.1298254,0.780837617,1.653810754,0.687570946,DB0042110041349_,0.37459026,0.122063108,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,152114,DB00524,10061428,40,1537,27,1317,0.386155383,1.269324146,0.755258882,2.163535678,0.556306719,DB0052410061428_,0.586435484,0.238484591,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,metolazone,DB00524
,152143,DB00695,10018358,37,28012,37,20491,0.195508233,0.731522344,0.450885007,1.186810758,0.343672435,DB0069510018358_,1.0680663,-0.312627513,NA,10018358,Glomerular filtration rate decreased,10022891,Investigations,Inv,furosemide,DB00695
,152147,DB00343,10028334,128,8608,49,5046,0.011887165,1.531250196,1.091383633,2.178374367,0.040862644,DB0034310028334_,3.197538979,0.426084523,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,diltiazem,DB00343
,152157,DB00410,10033425,35,1570,25,984,0.68766251,0.877499814,0.506925228,1.539564384,0.811687484,DB0041010033425_,0.208639884,-0.130678536,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,mupirocin,DB00410
,152158,DB01306,10033425,90,4118,64,3802,0.121876833,1.298295254,0.928862285,1.82367236,0.244078671,DB0130610033425_,1.410264682,0.261052061,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin aspart,DB01306
,152160,DB00620,10061818,46,4782,28,3104,0.812446244,1.066380311,0.650980965,1.775772056,0.899145261,DB0062010061818_,0.106310677,0.064270027,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,152163,DB01306,10061818,32,4176,32,3834,0.801972421,0.918121556,0.543471843,1.551052719,0.892892183,DB0130610061818_,0.113289441,-0.085425483,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,152164,DB00635,10037876,58,32995,18,23776,0.001061387,2.32186127,1.348230377,4.188679161,0.005787016,DB0063510037876_,5.15213856,0.842369135,NA,10037876,Rash papular,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,152166,DB00635,10040872,64,32989,23,23771,0.003221049,2.00503861,1.227422201,3.385105812,0.014334253,DB0063510040872_,4.245103272,0.695663317,NA,10040872,Skin infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,152174,DB14512,10053762,82,4762,32,2380,0.270500196,1.280715278,0.838821957,1.998199682,0.433185954,DB1451210053762_,0.836588189,0.247418733,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,mometasone furoate,DB14512
,152176,DB00316,10036772,30,65444,20,36933,0.558899503,0.846526537,0.464996339,1.572992334,0.711740192,DB0031610036772_,0.340042333,-0.166613728,NA,10036772,Proctalgia,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,152183,DB00635,10059866,51,33002,61,23733,0.007251797,0.601266035,0.406066266,0.887057281,0.027527481,DB0063510059866_,3.592570482,-0.508717789,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,152191,DB00007,10010774,18,1929,77,4375,0.013298641,0.530230977,0.297762269,0.897455978,0.044674393,DB0000710010774_,3.108354797,-0.634442561,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,leuprolide,DB00007
,152194,DB08875,10035664,20,623,39,1204,1,0.991073458,0.542717076,1.758433136,1,DB0887510035664_,0,-0.008966622,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cabozantinib,DB08875
,152195,DB09104,10013709,38,1012,23,849,0.241250039,1.38582942,0.797480749,2.457277962,0.399386382,DB0910410013709_,0.917825956,0.32629882,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,magnesium hydroxide,DB09104
,152197,DB00158,10020642,86,16729,35,8069,0.437143763,1.185145031,0.790594414,1.811269205,0.605646416,DB0015810020642_,0.501458936,0.169865156,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,152199,DB00381,10020642,172,29188,124,22763,0.518672893,1.081783006,0.853131193,1.374902241,0.677890822,DB0038110020642_,0.388769033,0.078610611,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,152203,DB00586,10020642,68,7041,14,2791,0.025961043,1.925226745,1.070380456,3.712891583,0.075602261,DB0058610020642_,2.582269093,0.655043751,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,diclofenac,DB00586
,152229,DB00741,10022086,40,4054,18,3156,0.062077378,1.729845129,0.966939788,3.212256563,0.147325528,DB0074110022086_,1.915110667,0.548031884,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,152236,DB00381,10022095,70,29290,37,22850,0.06343645,1.475908112,0.976918345,2.262631981,0.149679272,DB0038110022095_,1.899260458,0.38927347,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,152259,DB00186,10001949,77,16824,45,9963,1,1.013302238,0.691946108,1.499393392,1,DB0018610001949_,0,0.01321454,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,152261,DB01224,10007776,19,8089,66,5851,4.94569154912819e-11,0.20825271,0.117900869,0.3517083,1.69377853249296e-09,DB0122410007776_,20.19630399,-1.569002983,male,10007776,Catatonia,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,152265,DB01224,10012374,36,8072,16,5901,0.120981071,1.644792779,0.888789308,3.177787483,0.242856904,DB0122410012374_,1.41528288,0.497614406,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,152340,DB05676,10029148,94,47035,59,25270,0.351469102,0.855982072,0.611421322,1.206773026,0.521161276,DB0567610029148_,0.651695735,-0.155505847,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,apremilast,DB05676
,152341,DB05676,10062237,34,47095,20,25309,0.775909854,0.913588445,0.510897416,1.675303353,0.877822795,DB0567610062237_,0.130310533,-0.090375087,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,apremilast,DB05676
,152357,DB00773,10019211,28,2295,50,2777,0.108866395,0.677663483,0.409359099,1.101464388,0.224329977,DB0077310019211_,1.4946372,-0.389104452,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,etoposide,DB00773
,152376,DB00694,10043554,43,591,20,751,0.000229656,2.730150735,1.552125108,4.95514234,0.00161815,DB0069410043554_,6.426471736,1.004356822,female,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,daunorubicin,DB00694
,152377,DB00773,10045170,34,2289,44,2783,0.819427308,0.939489513,0.580237457,1.509498094,0.903751045,DB0077310045170_,0.101201349,-0.062418623,NA,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,etoposide,DB00773
,152410,DB01248,10047895,73,2627,36,1338,0.918511974,1.032793507,0.679714646,1.594210865,0.963988311,DB0124810047895_,0.03667611,0.032267273,NA,10047895,Weight decreased,10022891,Investigations,Inv,docetaxel,DB01248
,152429,DB00537,10001551,37,7520,13,4285,0.142366198,1.621715997,0.841369725,3.32865311,0.273115756,DB0053710001551_,1.297859561,0.483484846,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,ciprofloxacin,DB00537
,152442,DB01202,10002948,50,6664,48,5670,0.611181133,0.886301545,0.583391997,1.347727249,0.753242376,DB0120210002948_,0.283368222,-0.120698042,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,152445,DB00377,10003239,59,1060,23,700,0.037039455,1.693553803,1.019024361,2.901716089,0.09968077,DB0037710003239_,2.305782498,0.526829163,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,palonosetron,DB00377
,152447,DB00836,10003239,113,5422,49,4026,0.001688511,1.712268138,1.210932254,2.452113086,0.008461816,DB0083610003239_,4.772191529,0.537818888,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,loperamide,DB00836
,152448,DB01591,10003239,44,1911,6,650,0.03155744,2.493831466,1.052047965,7.194519558,0.088135504,DB0159110003239_,2.428879827,0.913820269,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,solifenacin,DB01591
,152451,DB00377,10010774,101,1018,60,663,0.613113638,1.096286051,0.776227945,1.558986526,0.754904065,DB0037710010774_,0.281164604,0.09192815,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,palonosetron,DB00377
,152453,DB01202,10010774,84,6630,61,5657,0.357412164,1.174941587,0.833208209,1.665023928,0.52711902,DB0120210010774_,0.640328912,0.161218433,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,levetiracetam,DB01202
,152457,DB00836,10011224,108,5427,58,4017,0.056977977,1.378234869,0.989895041,1.935704674,0.13774393,DB0083610011224_,1.982358897,0.3208036,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loperamide,DB00836
,152458,DB01069,10011224,152,6548,46,2349,0.369373525,1.185359226,0.844092421,1.692388985,0.539031828,DB0106910011224_,0.61798066,0.170045873,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,promethazine,DB01069
,152462,DB09146,10013573,41,747,16,411,0.319731499,1.409511069,0.762759605,2.725796012,0.487866278,DB0914610013573_,0.71771393,0.343242885,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,iron sucrose,DB09146
,152467,DB00537,10014020,43,7514,11,4287,0.015347373,2.230139206,1.129422976,4.801201327,0.050211438,DB0053710014020_,2.991512437,0.802064008,NA,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,ciprofloxacin,DB00537
,152470,DB00904,10014020,65,23004,24,14432,0.028653786,1.699100446,1.048762187,2.839465009,0.081719173,DB0090410014020_,2.504466633,0.530098962,NA,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,ondansetron,DB00904
,152482,DB01202,10017577,76,6638,77,5641,0.289456452,0.838781755,0.601558953,1.169343673,0.454617856,DB0120210017577_,0.78829809,-0.175804731,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,152486,DB00836,10019211,219,5316,76,3999,2.23212556099462e-09,2.167498268,1.656655415,2.861681178,5.77190559476082e-08,DB0083610019211_,16.66767846,0.77357363,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,152487,DB09146,10019211,39,749,17,410,0.477149094,1.255526081,0.683704099,2.398425567,0.642546438,DB0914610019211_,0.442316187,0.227554673,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,iron sucrose,DB09146
,152503,DB00537,10023232,56,7501,21,4277,0.121527103,1.520457673,0.904730897,2.647663952,0.243628868,DB0053710023232_,1.412109244,0.41901139,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,ciprofloxacin,DB00537
,152504,DB01069,10023232,51,6649,15,2380,0.576216555,1.216991963,0.672061983,2.334965362,0.725515959,DB0106910023232_,0.32087221,0.19638221,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,promethazine,DB01069
,152508,DB09146,10028813,100,688,28,399,0.000820405,2.070089473,1.322408384,3.330800656,0.004676716,DB0914610028813_,5.365159076,0.72759183,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,iron sucrose,DB09146
,152526,DB00537,10039101,48,7509,17,4281,0.093831763,1.609678389,0.90779573,2.989690977,0.201500645,DB0053710039101_,1.601962695,0.476034401,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ciprofloxacin,DB00537
,152527,DB00836,10039101,48,5487,15,4060,0.002964656,2.367559641,1.30110448,4.558540729,0.013372114,DB0083610039101_,4.314583786,0.861859738,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loperamide,DB00836
,152528,DB00904,10039101,128,22941,70,14386,0.380144394,1.146700371,0.849605714,1.558536562,0.550301274,DB0090410039101_,0.59728938,0.136888576,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,152547,DB00425,10046543,38,12657,15,7469,0.202346921,1.494912372,0.802708767,2.927467814,0.35174187,DB0042510046543_,1.044857697,0.402067591,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,zolpidem,DB00425
,152555,DB01069,10047571,63,6637,7,2388,0.000973699,3.23808858,1.480033628,8.392826111,0.005389846,DB0106910047571_,5.223238387,1.174983211,female,10047571,Visual impairment,10015919,Eye disorders,Eye,promethazine,DB01069
,152574,DB00316,10061218,99,65375,37,36916,0.031935477,1.510896264,1.025812448,2.268708853,0.088967796,DB0031610061218_,2.419480819,0.412703027,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,152586,DB00425,10068319,104,12591,22,7462,1.76689503915713e-06,2.801463785,1.754153383,4.666790921,2.37377133167622e-05,DB0042510068319_,10.6484455,1.030142061,female,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,152587,DB00836,10068319,35,5500,19,4056,0.334227146,1.358425606,0.75478975,2.517595381,0.503340793,DB0083610068319_,0.686487818,0.306326386,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loperamide,DB00836
,152588,DB00904,10068319,170,22899,52,14404,2.12975430936227e-06,2.056380366,1.498113344,2.864453889,2.80042981598736e-05,DB0090410068319_,10.48315255,0.720947334,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,152599,DB00433,10060800,43,7613,11,6009,0.000472219,3.085170799,1.562908179,6.641353802,0.002944784,DB0043310060800_,5.827719668,1.12660702,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,prochlorperazine,DB00433
,152600,DB00497,10060800,89,19178,41,16334,0.001034112,1.848787458,1.262614962,2.747681949,0.005664018,DB0049710060800_,5.173621736,0.614529996,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,oxycodone,DB00497
,152604,DB01373,10060800,167,22553,44,7337,0.228965215,1.234732045,0.880126981,1.764713586,0.384657464,DB0137310060800_,0.955402044,0.210853979,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,calcium,DB01373
,152605,DB00203,10074903,27,13851,76,8862,1.37886547204583e-12,0.227316081,0.140707051,0.35716783,6.0755802074279e-11,DB0020310074903_,23.52415853,-1.481413805,male,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,152618,DB08910,10003239,123,16621,81,17407,0.001193378,1.590295722,1.190683668,2.133804718,0.006379487,DB0891010003239_,5.054667565,0.463919987,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pomalidomide,DB08910
,152620,DB08910,10019211,210,16534,115,17373,1.38286043773243e-08,1.918699563,1.519698507,2.432597856,3.00826886746017e-07,DB0891010019211_,15.01673086,0.651647646,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,152625,DB08910,10038683,41,16703,42,17446,1,1.019617006,0.646295865,1.607555986,1,DB0891010038683_,0,0.019427072,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,152626,DB00682,10022687,58,19401,34,16330,0.094733672,1.435839628,0.924012388,2.262882646,0.202857399,DB0068210022687_,1.595252017,0.361749785,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,152627,DB00557,10037153,93,5894,35,3032,0.132150542,1.36684707,0.914971257,2.083410488,0.258893717,DB0055710037153_,1.35133766,0.312506678,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxyzine,DB00557
,152630,DB00169,10037437,46,38645,24,18151,0.70092244,0.900236667,0.538060104,1.542459235,0.820314993,DB0016910037437_,0.198066875,-0.105097586,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,152633,DB00722,10037437,34,25369,39,25993,0.641566899,0.89324068,0.546780843,1.452728154,0.778200742,DB0072210037437_,0.250770765,-0.112899216,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,152637,DB00169,10043709,52,38639,12,18163,0.02250234,2.036943605,1.072689735,4.193631061,0.067724739,DB0016910043709_,2.692303747,0.711450452,NA,10043709,Thyroid disorder,10014698,Endocrine disorders,Endo,cholecalciferol,DB00169
,152645,DB11750,10047895,36,2464,33,1480,0.10256253,0.655350605,0.395238516,1.089700594,0.214869174,DB1175010047895_,1.53772593,-0.422584912,NA,10047895,Weight decreased,10022891,Investigations,Inv,clobetasol,DB11750
,152646,DB00230,10050296,77,19597,31,8620,0.753787597,1.092558451,0.710849248,1.716943209,0.861560507,DB0023010050296_,0.149009991,0.088522149,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,152658,DB00108,10020772,80,10114,19,3276,0.242300082,1.36377337,0.817626817,2.38624593,0.400531894,DB0010810020772_,0.914961879,0.310255395,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,natalizumab,DB00108
,152669,DB00178,10037660,21,1416,32,1648,0.404776799,0.763837469,0.416574969,1.37323335,0.574521203,DB0017810037660_,0.554218276,-0.26940025,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ramipril,DB00178
,152693,DB00863,10027175,113,10560,36,5804,0.004335218,1.725147129,1.174344332,2.588898752,0.018230735,DB0086310027175_,4.004646381,0.545312339,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,152694,DB01065,10027175,65,4266,28,3023,0.033490392,1.644916777,1.038233955,2.668205314,0.092332175,DB0106510027175_,2.382362606,0.497689791,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,melatonin,DB01065
,152704,DB01068,10027940,38,13725,17,6823,0.775934181,1.111204003,0.611676048,2.101159374,0.877822795,DB0106810027940_,0.130310533,0.105444115,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,152706,DB00472,10038743,35,10724,27,4285,0.011233152,0.517962114,0.304217726,0.890969855,0.039075273,DB0047210038743_,3.242265408,-0.657853179,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,152719,DB00437,10040070,40,6881,58,11488,0.530438799,1.151381793,0.748923041,1.754521165,0.687470235,DB0043710040070_,0.374736745,0.14096278,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,allopurinol,DB00437
,152723,DB00227,10046571,51,2416,16,1787,0.002506145,2.357186966,1.317314709,4.443974985,0.011681865,DB0022710046571_,4.449717675,0.857468944,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,lovastatin,DB00227
,152724,DB00683,10013700,90,1494,30,1608,6.56121710721346e-09,3.227827295,2.099736675,5.087327968,1.53367355858698e-07,DB0068310013700_,15.69042977,1.171809247,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,midazolam,DB00683
,152732,DB08893,10048959,33,2052,20,1038,0.558444868,0.834710596,0.462377825,1.54322064,0.711384921,DB0889310048959_,0.340541616,-0.180670206,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,mirabegron,DB08893
,152734,DB00641,10074903,64,14060,35,12440,0.025959261,1.617848561,1.054501884,2.519344989,0.075601259,DB0064110074903_,2.582282337,0.481097218,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,152738,DB00115,10016334,70,18355,14,10458,9.58246757006544e-05,2.848719989,1.589022692,5.480704451,0.000768263,DB0011510016334_,7.171377897,1.046869767,female,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,152745,DB00230,10020100,68,19606,28,8623,0.824957575,1.068117363,0.677970611,1.724452393,0.907364962,DB0023010020100_,0.097210526,0.065897625,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,152752,DB00996,10020100,106,38847,50,22375,0.279106782,1.221023299,0.864099237,1.745951733,0.442936008,DB0099610020100_,0.814329972,0.199689277,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,152773,DB00331,10048439,52,24894,6,20746,1.3617329543686e-08,7.22232305,3.102360412,20.57937642,2.96915393658886e-07,DB0033110048439_,15.02981861,1.977176653,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,152782,DB00115,10062244,76,18349,22,10450,0.004273202,1.967366369,1.209787573,3.323756502,0.018023284,DB0011510062244_,4.016090819,0.67669578,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,152783,DB00230,10062244,55,19619,12,8639,0.023828405,2.018174915,1.067140864,4.142753074,0.070835743,DB0023010062244_,2.647391565,0.702193596,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,152790,DB00996,10062244,78,38875,31,22394,0.090235178,1.44941118,0.94439955,2.274976037,0.195616803,DB0099610062244_,1.631597619,0.371157391,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,152801,DB00787,10013395,19,16981,54,17194,5.13323715172783e-05,0.356252346,0.199339424,0.611073262,0.000452017,DB0078710013395_,7.701790294,-1.032115963,male,10013395,Disorientation,10037175,Psychiatric disorders,Psych,acyclovir,DB00787
,152804,DB00537,10009887,44,7513,27,4271,0.804643208,0.926421085,0.560151314,1.558245232,0.894419007,DB0053710009887_,0.111580926,-0.076426412,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,ciprofloxacin,DB00537
,152808,DB00126,10054236,46,10125,19,5926,0.246130754,1.416973917,0.813129506,2.563441705,0.405068207,DB0012610054236_,0.903699813,0.348523554,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,152834,DB00641,10013990,38,14086,34,12441,1,0.987124086,0.604620256,1.617585078,1,DB0064110013990_,0,-0.012959527,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,simvastatin,DB00641
,152835,DB00758,10013990,22,8278,30,10044,0.780547419,0.889804934,0.488647402,1.596376435,0.880525693,DB0075810013990_,0.127236172,-0.116753016,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,clopidogrel,DB00758
,152837,DB00381,10031009,86,29274,47,22840,0.054004416,1.427615044,0.988727865,2.083786103,0.132490636,DB0038110031009_,2.021243306,0.356005251,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,152852,DB01076,10010144,154,25593,202,25381,0.009139711,0.756067721,0.608568313,0.937775945,0.033127266,DB0107610010144_,3.407398592,-0.279624328,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,152853,DB01175,10010144,428,10296,227,4665,0.064190477,0.854302119,0.722809087,1.011713718,0.150990798,DB0117510010144_,1.890536381,-0.157470379,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,152860,DB00646,10050584,47,3406,15,1985,0.046192852,1.825906744,1,3.52525901,0.117870024,DB0064610050584_,2.138172754,0.602076709,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,nystatin,DB00646
,152861,DB08828,10001760,136,626,165,977,0.047168349,1.286205257,0.995068968,1.660827447,0.119766234,DB0882810001760_,2.122213486,0.251696222,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,vismodegib,DB08828
,152862,DB08828,10012735,47,715,66,1076,0.766698542,1.071627937,0.712137499,1.60207634,0.87159878,DB0882810012735_,0.137426076,0.069178928,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,vismodegib,DB08828
,152863,DB08828,10028411,18,744,37,1105,0.328305073,0.722656436,0.384204063,1.313408534,0.49690024,DB0882810028411_,0.699365998,-0.324821362,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,vismodegib,DB08828
,152905,DB00635,10020096,53,33000,20,23774,0.01243882,1.909093829,1.122003985,3.372361876,0.042355757,DB0063510020096_,3.161650921,0.646628695,NA,10020096,Hip arthroplasty,10042613,Surgical and medical procedures,Surg,prednisone,DB00635
,152920,DB00641,10007554,47,14077,52,12423,0.268673798,0.797656966,0.525585136,1.207712339,0.431088437,DB0064110007554_,0.841442019,-0.226076642,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,simvastatin,DB00641
,152932,DB00065,10040753,57,9407,14,4943,0.008312318,2.139273017,1.175501862,4.161978275,0.03070179,DB0006510040753_,3.483434324,0.76046606,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,infliximab,DB00065
,152936,DB01098,10008469,42,8107,44,7165,0.449662308,0.84364223,0.538677298,1.319601586,0.617296378,DB0109810008469_,0.482406016,-0.170026773,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,152937,DB01098,10020642,61,8088,39,7170,0.131248468,1.38654224,0.911536986,2.131480081,0.257549275,DB0109810020642_,1.356544217,0.326813051,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,rosuvastatin,DB01098
,152951,DB01136,10007556,16,9868,41,11074,0.004838411,0.437969669,0.22926669,0.798134384,0.019944489,DB0113610007556_,3.914802419,-0.82560562,NA,10007556,Cardiac failure acute,10007541,Cardiac disorders,Card,carvedilol,DB01136
,152954,DB00008,10028411,42,1483,35,1641,0.248360837,1.327724227,0.822628132,2.154710433,0.407717241,DB0000810028411_,0.897181381,0.283466369,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,peginterferon alfa-2a,DB00008
,152957,DB08910,10028334,233,16511,185,17303,0.005008328,1.31985733,1.082177432,1.611662529,0.020490917,DB0891010028334_,3.887773588,0.277523648,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,pomalidomide,DB08910
,152960,DB00480,10003662,25,67403,99,67563,1.28225109004802e-11,0.253144883,0.156324138,0.395856292,4.80113531366272e-10,DB0048010003662_,21.45699852,-1.373793294,male,10003662,Atrial flutter,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,152977,DB00327,10012218,63,6075,46,4216,0.844891552,0.950493388,0.638250865,1.424805803,0.921664811,DB0032710012218_,0.081573667,-0.050774073,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,hydromorphone,DB00327
,152978,DB05676,10035664,280,46849,139,25190,0.472043786,1.083112431,0.880140096,1.337893297,0.638123376,DB0567610035664_,0.449223635,0.079838777,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,apremilast,DB05676
,153015,DB00836,10000060,53,5482,42,4033,0.754709041,0.928366272,0.606240971,1.429642662,0.862276239,DB0083610000060_,0.148179597,-0.074328934,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,153018,DB04868,10000087,30,1611,24,1492,0.680729314,1.157611854,0.650944176,2.079372288,0.806956762,DB0486810000087_,0.214485191,0.146359136,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,nilotinib,DB04868
,153025,DB04868,10028813,121,1520,61,1455,6.37667475425581e-05,1.898396175,1.371809093,2.649529734,0.000542342,DB0486810028813_,7.519613158,0.641009411,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,nilotinib,DB04868
,153026,DB04868,10033645,29,1612,66,1450,2.37535521219504e-05,0.39534687,0.244800587,0.624616769,0.000231245,DB0486810033645_,8.372031814,-0.927991748,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,nilotinib,DB04868
,153027,DB04868,10047700,50,1591,30,1486,0.069182892,1.556452176,0.964680376,2.550090366,0.159865698,DB0486810047700_,1.833421204,0.442408985,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,nilotinib,DB04868
,153032,DB00451,10021113,43,47228,8,15411,0.191508181,1.753834271,0.814904123,4.320212832,0.33852001,DB0045110021113_,1.083172075,0.561804403,NA,10021113,Hypothermia,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,153043,DB00956,10013654,165,5649,208,3259,2.0331576863006e-13,0.457684348,0.369087316,0.566846016,1.00171602220077e-11,DB0095610013654_,25.32672147,-0.78157553,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,hydrocodone,DB00956
,153044,DB00169,10073317,55,38636,20,18155,0.386001718,1.292171543,0.761952702,2.277028947,0.556146307,DB0016910073317_,0.586723878,0.25632417,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,153045,DB00381,10073317,53,29307,37,22850,0.67097966,1.116797221,0.719920585,1.748971927,0.800371966,DB0038110073317_,0.222678702,0.110464965,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,153049,DB00758,10043554,40,8260,78,9996,0.015525043,0.62061682,0.412460423,0.921044676,0.050636028,DB0075810043554_,2.983091935,-0.477041424,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,clopidogrel,DB00758
,153054,DB00421,10007617,32,8871,19,5233,1,0.993514676,0.545645647,1.857143031,1,DB0042110007617_,0,-0.006506445,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,spironolactone,DB00421
,153058,DB00264,10017626,41,29566,38,24854,0.734822992,0.906995274,0.568782882,1.449600127,0.846677144,DB0026410017626_,0.166435833,-0.097618039,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,metoprolol,DB00264
,153061,DB00695,10017626,48,28001,22,20506,0.069944516,1.597794752,0.94568613,2.780455211,0.161200492,DB0069510017626_,1.825106398,0.468624399,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,furosemide,DB00695
,153078,DB00441,10035528,52,2222,40,1854,0.7512684,1.084707067,0.700976202,1.689421906,0.859540781,DB0044110035528_,0.151357008,0.081309966,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,gemcitabine,DB00441
,153081,DB09020,10035528,30,1924,24,1580,1,1.026502911,0.577549715,1.842861607,1,DB0902010035528_,0,0.026157794,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,bisacodyl,DB09020
,153085,DB00448,10035664,153,4992,104,3020,0.395556786,0.890016267,0.686297921,1.157948706,0.565203996,DB0044810035664_,0.570568558,-0.116515539,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,lansoprazole,DB00448
,153129,DB00758,10061822,39,8261,53,10021,0.601655451,0.892647324,0.574125434,1.377059567,0.745932434,DB0075810061822_,0.293120253,-0.113563711,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,153135,DB00758,10020642,47,8253,58,10016,1,0.983449756,0.65408564,1.471947906,1,DB0075810020642_,0,-0.016688729,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,clopidogrel,DB00758
,153136,DB00335,10060800,37,8429,21,5444,0.68762283,1.137973973,0.648127419,2.048520657,0.811687484,DB0033510060800_,0.208639884,0.129249464,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,atenolol,DB00335
,153140,DB00334,10002855,78,2771,60,2752,0.143835635,1.291024596,0.906244164,1.846905428,0.275265151,DB0033410002855_,1.29002046,0.255436164,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,153142,DB00695,10012374,61,27988,15,20513,5.79913145585595e-05,2.980435185,1.67305004,5.647262488,0.000501085,DB0069510012374_,7.598734067,1.092069325,female,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,153153,DB01015,10060795,31,9856,36,9345,0.463039445,0.816475792,0.487957073,1.358879272,0.630182947,DB0101510060795_,0.46174511,-0.202758016,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,153160,DB01068,10042128,48,13715,10,6830,0.011189154,2.390290012,1.19317837,5.302368389,0.038941665,DB0106810042128_,3.245690521,0.871414703,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,153181,DB00480,10013952,264,67164,217,67445,0.031704414,1.221675905,1.016632298,1.469328546,0.088442614,DB0048010013952_,2.425401364,0.200223608,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,153193,DB01098,10029354,49,8100,32,7177,0.182715045,1.356733636,0.850588301,2.19166826,0.327325929,DB0109810029354_,1.116798879,0.305080073,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,rosuvastatin,DB01098
,153195,DB01067,10035528,48,4313,47,4776,0.605921015,1.130894376,0.738788804,1.73205148,0.748942365,DB0106710035528_,0.289093247,0.123008802,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,glipizide,DB01067
,153233,DB00264,10023644,43,29564,43,24849,0.449103651,0.840520271,0.537585249,1.314152875,0.616738824,DB0026410023644_,0.483309645,-0.173734209,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,metoprolol,DB00264
,153234,DB00338,10023644,66,33608,31,22241,0.120246208,1.408935656,0.906025132,2.234925907,0.241697424,DB0033810023644_,1.420068649,0.342834565,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,omeprazole,DB00338
,153246,DB01015,10037868,31,9856,33,9348,0.707604992,0.890981362,0.527287927,1.502041564,0.82522782,DB0101510037868_,0.192095786,-0.11543177,NA,10037868,Rash maculo-papular,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,153260,DB00482,10042458,45,8214,11,3060,0.230920293,1.523887097,0.774816704,3.271660647,0.387026711,DB0048210042458_,0.949261568,0.421264371,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,celecoxib,DB00482
,153274,DB00762,10043554,32,1131,42,1327,0.722753401,0.893995688,0.542252514,1.461256289,0.836842197,DB0076210043554_,0.17811976,-0.112054328,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,irinotecan,DB00762
,153291,DB00999,10013036,40,21390,16,12223,0.266568251,1.428573568,0.781990532,2.733766044,0.428756974,DB0099910013036_,0.846865014,0.356676441,NA,10013036,Diplopia,10015919,Eye disorders,Eye,hydrochlorothiazide,DB00999
,153305,DB00169,10038683,63,38628,36,18139,0.38806462,0.821788838,0.537022893,1.274838766,0.558047899,DB0016910038683_,0.583310479,-0.196271806,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,153306,DB00381,10038683,63,29297,34,22853,0.100759787,1.4453668,0.937528152,2.263452263,0.212018519,DB0038110038683_,1.551081654,0.36836313,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,153308,DB00480,10038683,102,67326,103,67559,1,0.99371818,0.748081068,1.319939901,1,DB0048010038683_,0,-0.006301634,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,153311,DB00722,10038683,33,25370,24,26008,0.233020816,1.409562101,0.807957386,2.493109791,0.389553657,DB0072210038683_,0.942753665,0.343279089,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,153312,DB00761,10038683,41,15266,21,8604,0.79188773,1.100379786,0.634894861,1.961396285,0.887301788,DB0076110038683_,0.11957012,0.09565538,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,153313,DB00787,10038683,18,16982,33,17215,0.049006829,0.552950916,0.293030746,1.011429326,0.123131912,DB0078710038683_,2.094499045,-0.59248604,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,153334,DB00575,10050584,37,5207,17,3812,0.128444167,1.593294035,0.873465567,3.022332393,0.253436544,DB0057510050584_,1.372641807,0.465803593,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,clonidine,DB00575
,153344,DB08931,10000081,183,6394,44,2402,0.007966706,1.562404553,1.114743912,2.23123602,0.029694029,DB0893110000081_,3.516809303,0.446226014,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,153347,DB00257,10013968,62,890,32,590,0.278431427,1.284210425,0.813776459,2.060630525,0.442236393,DB0025710013968_,0.815910714,0.250144074,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clotrimazole,DB00257
,153348,DB00654,10013968,122,3694,62,2536,0.057103377,1.350829261,0.982650699,1.872802799,0.137981455,DB0065410013968_,1.980635985,0.300718671,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,latanoprost,DB00654
,153350,DB00540,10019211,118,2365,31,1060,0.008240365,1.705833732,1.131697826,2.640048174,0.030498167,DB0054010019211_,3.490088699,0.534053984,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,nortriptyline,DB00540
,153351,DB08932,10040070,97,19346,31,6566,0.838859779,1.061976454,0.70152034,1.648640128,0.917350195,DB0893210040070_,0.086265987,0.060131751,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,macitentan,DB08932
,153359,DB00295,10013946,39,14624,24,9578,0.89757941,1.064300763,0.623697437,1.851367845,0.956338178,DB0029510013946_,0.044643686,0.062318023,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,153380,DB00924,10035528,56,10106,35,4216,0.065123489,0.667504877,0.429192984,1.05101093,0.152652686,DB0092410035528_,1.879589962,-0.404208582,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,cyclobenzaprine,DB00924
,153387,DB00153,10047899,149,7274,44,3395,0.007767646,1.580459341,1.119215431,2.271478737,0.029088557,DB0015310047899_,3.537410421,0.457715527,NA,10047899,Weight increased,10022891,Investigations,Inv,ergocalciferol,DB00153
,153438,DB00950,10000059,63,4655,22,2034,0.407428914,1.251199532,0.756919792,2.141669867,0.576908316,DB0095010000059_,0.550071923,0.224102717,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,fexofenadine,DB00950
,153441,DB01306,10000059,52,4156,27,3839,0.017000347,1.778894994,1.094513567,2.95218248,0.054388282,DB0130610000059_,2.91160656,0.575992382,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,insulin aspart,DB01306
,153442,DB01590,10000059,50,4688,36,2831,0.434766913,0.838751946,0.534138988,1.328837445,0.603243681,DB0159010000059_,0.505434049,-0.175840271,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,everolimus,DB01590
,153443,DB06605,10000059,183,13890,81,12952,9.14959760113893e-09,2.106545092,1.611280938,2.774652351,2.07504031877426e-07,DB0660510000059_,15.38811507,0.745049208,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,153451,DB01075,10003119,33,19915,21,11076,0.670469757,0.873980211,0.490520819,1.590320891,0.800083838,DB0107510003119_,0.22303876,-0.134697545,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,153468,DB01075,10009887,71,19877,34,11063,0.540741732,1.162231708,0.761399818,1.805652518,0.69622319,DB0107510009887_,0.362084995,0.150342043,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,153476,DB00904,10012601,48,23021,33,14423,0.731950649,0.911298047,0.572700562,1.466190805,0.844218732,DB0090410012601_,0.169343657,-0.092885271,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,153480,DB01075,10012601,36,19912,20,11077,1,1.001335837,0.564063113,1.826508955,1,DB0107510012601_,0,0.001334946,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,diphenhydramine,DB01075
,153484,DB01013,10012735,83,934,65,542,0.090602494,0.741158631,0.519709999,1.060443787,0.196169352,DB0101310012735_,1.628776952,-0.2995406,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,clobetasol propionate,DB01013
,153486,DB00169,10013538,129,38562,41,18134,0.031867327,1.479575461,1.033367118,2.158263593,0.088812492,DB0016910013538_,2.421227963,0.391755196,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,153488,DB00904,10013538,96,22973,36,14420,0.007173375,1.67382573,1.129503095,2.529787035,0.027307335,DB0090410013538_,3.600599921,0.515111863,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,153489,DB00916,10013538,81,5242,47,2384,0.211376842,0.783838788,0.538664649,1.151909598,0.363021254,DB0091610013538_,1.013293896,-0.243551907,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,metronidazole,DB00916
,153496,DB06605,10013538,33,14040,29,13004,0.899025937,1.053978401,0.620070436,1.800514819,0.956490275,DB0660510013538_,0.044484657,0.052571957,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,apixaban,DB06605
,153502,DB01075,10016766,41,19907,28,11069,0.450659315,0.814212602,0.491188175,1.367877649,0.618374405,DB0107510016766_,0.480661171,-0.205533766,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,153505,DB06605,10016766,49,14024,32,13001,0.147289575,1.419528237,0.890423842,2.291897276,0.280148086,DB0660510016766_,1.272436937,0.350324589,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,153512,DB06605,10016825,96,13977,55,12978,0.004175273,1.620663701,1.150484493,2.302683413,0.017686875,DB0660510016825_,4.034932442,0.482835758,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,apixaban,DB06605
,153513,DB01013,10019211,81,936,32,575,0.043555734,1.554586824,1.005845551,2.452695514,0.112738797,DB0101310019211_,2.18268167,0.441209802,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,clobetasol propionate,DB01013
,153528,DB04861,10028334,31,1934,20,1367,0.776811056,1.09557218,0.60196301,2.037293775,0.878384143,DB0486110028334_,0.12967126,0.091276765,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,nebivolol,DB04861
,153529,DB06605,10028334,129,13944,80,12953,0.004359888,1.497871898,1.123371052,2.007507005,0.01831104,DB0660510028334_,4.000251122,0.404045366,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,153549,DB01118,10033557,26,3037,36,4673,0.696848177,1.111258476,0.642888048,1.896590693,0.817604014,DB0111810033557_,0.20137715,0.105493135,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,amiodarone,DB01118
,153552,DB06605,10033557,142,13931,50,12983,4.06188343900701e-10,2.646464802,1.903011476,3.733819172,1.21187975248921e-08,DB0660510033557_,18.22850808,0.973224712,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,apixaban,DB06605
,153554,DB01013,10037844,44,973,23,584,0.699120877,1.148155993,0.670509924,2.013781175,0.819076564,DB0101310037844_,0.199577715,0.138157171,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,clobetasol propionate,DB01013
,153555,DB04861,10037844,53,1912,20,1367,0.015824344,1.894293996,1.107624582,3.361575136,0.051408092,DB0486110037844_,2.967959683,0.638846208,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,nebivolol,DB04861
,153562,DB00207,10042128,39,9041,18,5437,0.411699924,1.302948695,0.72699138,2.422357116,0.5811779,DB0020710042128_,0.542698373,0.264629923,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,153563,DB00904,10042128,232,22837,104,14352,0.004045843,1.401922985,1.106646997,1.785898153,0.0172442,DB0090410042128_,4.06027945,0.337844855,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,153568,DB06605,10042128,32,14041,19,13014,0.125463479,1.560991008,0.857811322,2.916377244,0.2493145,DB0660510042128_,1.389040125,0.445320881,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,153574,DB01075,10043224,44,19904,12,11085,0.025410253,2.042008323,1.059600221,4.249117917,0.07439805,DB0107510043224_,2.598325554,0.713933796,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,153586,DB00207,10048959,81,8999,37,5418,0.181670883,1.318014126,0.881489472,2.003833633,0.326020288,DB0020710048959_,1.120795666,0.276126154,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,153587,DB00254,10048959,89,5846,48,3340,0.788838863,1.059341141,0.735550628,1.541932806,0.885584365,DB0025410048959_,0.121507553,0.05764715,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,153589,DB01590,10048959,133,4605,72,2795,0.465592196,1.121175791,0.83197149,1.521146696,0.632394113,DB0159010048959_,0.458242483,0.114377948,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,153590,DB04861,10048959,45,1920,21,1366,0.1297517,1.524368659,0.884681824,2.707101926,0.255307365,DB0486110048959_,1.365287108,0.42158033,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,nebivolol,DB04861
,153592,DB01234,10041541,51,31574,56,32832,0.846656043,0.946983255,0.634884019,1.409765977,0.922998542,DB0123410041541_,0.080127624,-0.054473868,NA,10041541,Spinal compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,153613,DB00706,10020751,6,1069,90,15835,1,0.987527964,0.352244557,2.242083354,1,DB0070610020751_,0,-0.012550465,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,tamsulosin,DB00706
,153616,DB01222,10021097,108,9166,95,5310,0.003356972,0.658637009,0.494184875,0.878946205,0.014806278,DB0122210021097_,4.212704015,-0.417582717,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,budesonide,DB01222
,153623,DB01222,10028836,53,9221,12,5393,0.001783708,2.582988136,1.361245123,5.315121971,0.008852026,DB0122210028836_,4.727108964,0.948946921,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,budesonide,DB01222
,153635,DB00046,10035226,21,5438,34,4658,0.021283179,0.529093859,0.29138988,0.939720909,0.064955398,DB0004610035226_,2.734054426,-0.636589436,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,insulin lispro,DB00046
,153636,DB00047,10035226,37,9248,48,8470,0.127369431,0.70600433,0.446554253,1.108184831,0.251924369,DB0004710035226_,1.378626359,-0.348133908,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,insulin glargine,DB00047
,153639,DB01050,10035226,34,18074,48,9323,6.40326972925218e-06,0.365388857,0.228156473,0.579347473,7.34496602702176e-05,DB0105010035226_,9.518910281,-1.006793131,male,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ibuprofen,DB01050
,153647,DB06292,10037844,43,1314,30,1203,0.285584695,1.312113482,0.79848434,2.181349376,0.450197536,DB0629210037844_,0.798068824,0.271639183,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dapagliflozin,DB06292
,153649,DB00175,10001760,113,8018,20,6086,5.90787063194883e-12,4.288195234,2.646210196,7.294928101,2.35107311976949e-10,DB0017510001760_,22.17097906,1.455865953,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,pravastatin,DB00175
,153650,DB00480,10001760,557,66871,112,67550,1.62664187870423e-72,5.023445365,4.092637215,6.212212605,1.94346735371548e-69,DB0048010001760_,158.2138977,1.614116026,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,153651,DB00927,10001760,92,7405,21,4995,1.53777264655573e-06,2.954896432,1.821261569,5.006447413,2.10510214350645e-05,DB0092710001760_,10.76856147,1.083463602,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,famotidine,DB00927
,153653,DB00480,10011878,86,67342,68,67594,0.147158688,1.269433217,0.912677508,1.771747035,0.279980707,DB0048010011878_,1.27303458,0.238570515,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,lenalidomide,DB00480
,153659,DB00758,10027175,81,8219,66,10008,0.015836617,1.494357964,1.064868648,2.103611766,0.05144072,DB0075810027175_,2.967325204,0.401696659,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,153660,DB00480,10028810,911,66517,646,67016,8.98114167870796e-12,1.420785447,1.282362603,1.574850347,3.45635884370189e-10,DB0048010028810_,21.78563525,0.35120985,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,153661,DB00758,10028810,97,8203,55,10019,3.81124179923859e-06,2.154002281,1.529537386,3.060110392,4.65405299386696e-05,DB0075810028810_,9.975187013,0.767327638,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,clopidogrel,DB00758
,153662,DB00927,10028810,112,7385,39,4977,0.000299493,1.935298151,1.330651059,2.867870548,0.002015146,DB0092710028810_,6.207063629,0.660261398,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,famotidine,DB00927
,153668,DB01234,10037437,90,31535,102,32786,0.563772188,0.917379462,0.682843247,1.230660449,0.715674296,DB0123410037437_,0.33453011,-0.086234084,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,153671,DB00091,10040047,57,5453,43,2627,0.031455957,0.638628713,0.421088047,0.974847579,0.087917467,DB0009110040047_,2.431356776,-0.448432037,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,cyclosporine,DB00091
,153696,DB00215,10005724,35,11068,20,5256,0.563309703,0.831069572,0.466153847,1.520847424,0.715329028,DB0021510005724_,0.335012664,-0.185041767,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,citalopram,DB00215
,153716,DB00190,10031127,25,3272,46,4628,0.333411401,0.768734624,0.451621032,1.280558722,0.502434782,DB0019010031127_,0.688289435,-0.263009462,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,carbidopa,DB00190
,153718,DB00190,10042772,38,3259,55,4619,1,0.979230838,0.628439753,1.51171215,1,DB0019010042772_,0,-0.020987875,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,153722,DB00374,10043554,69,17647,17,5707,0.37871537,1.312587589,0.76279924,2.383127633,0.548689138,DB0037410043554_,0.600223232,0.272000448,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,treprostinil,DB00374
,153747,DB13867,10028735,58,4492,15,2539,0.00655149,2.185332705,1.219366938,4.161002486,0.025400975,DB1386710028735_,3.672967701,0.781768085,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,153751,DB00005,10002368,50,128032,15,42404,0.885890695,1.103993394,0.609905234,2.117033755,0.952535694,DB0000510002368_,0.048627699,0.098933964,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,153753,DB01068,10027951,57,13706,12,6828,0.004562832,2.366252014,1.254315545,4.848468565,0.01898141,DB0106810027951_,3.964295178,0.861307275,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,153754,DB01224,10027951,48,8060,13,5904,0.000988893,2.704435375,1.440638285,5.445800818,0.0054532,DB0122410027951_,5.211552632,0.994893157,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,153756,DB00563,10037383,73,46573,22,15326,0.812169285,1.091927882,0.669797659,1.848289393,0.89905753,DB0056310037383_,0.106408254,0.087944833,NA,10037383,Pulmonary fibrosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,153790,DB00820,10003481,47,11868,32,5784,0.150324083,0.715803565,0.446676158,1.160591765,0.284407149,DB0082010003481_,1.257348444,-0.3343495,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,tadalafil,DB00820
,153796,DB00381,10061422,24,29336,36,22851,0.013087545,0.519308696,0.296301791,0.895043205,0.044128809,DB0038110061422_,3.120642452,-0.655256782,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,153808,DB06605,10046274,40,14033,64,12969,0.007638032,0.577628327,0.378780436,0.871476347,0.028707466,DB0660510046274_,3.550598055,-0.54882465,NA,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,153810,DB06605,10047700,327,13746,153,12880,4.22731494625851e-13,2.002549301,1.645204137,2.446291647,1.98952503782283e-11,DB0660510047700_,24.64054009,0.694421019,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,153823,DB00381,10009657,43,29317,39,22848,0.505605317,0.859280242,0.543803297,1.361536968,0.666457839,DB0038110009657_,0.405778399,-0.151660168,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,amlodipine,DB00381
,153848,DB00381,10017944,132,29228,77,22810,0.042906928,1.337847289,1.001977508,1.796827115,0.111504138,DB0038110017944_,2.193693576,0.291061821,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,153852,DB01592,10017944,33,6243,23,3044,0.199819916,0.699588915,0.397812661,1.250197092,0.348802397,DB0159210017944_,1.053249716,-0.357262381,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,153853,DB09140,10017944,36,3705,18,1780,0.884593048,0.960882346,0.529824939,1.80268614,0.951939928,DB0914010017944_,0.049253347,-0.039903306,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,oxygen,DB09140
,153855,DB00047,10023676,34,9251,21,8497,0.176514222,1.487049861,0.837837809,2.698551557,0.319360981,DB0004710023676_,1.141433215,0.396794198,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,insulin glargine,DB00047
,153883,DB06724,10010264,133,7796,30,3889,3.47297919012919e-05,2.211421323,1.475863502,3.412465013,0.000322741,DB0672410010264_,8.038660785,0.793635441,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,153884,DB00215,10023232,82,11021,19,5257,0.003691113,2.058546388,1.236701286,3.596016091,0.01599158,DB0021510023232_,4.13569296,0.722000097,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,153885,DB08904,10023232,125,11485,18,3541,0.001417252,2.140876888,1.298322968,3.735705719,0.007333163,DB0890410023232_,4.915348285,0.761215506,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,certolizumab pegol,DB08904
,153886,DB08904,10033425,164,11446,36,3523,0.077247684,1.402119869,0.970404123,2.075536423,0.173669365,DB0890410033425_,1.750601988,0.337985284,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,certolizumab pegol,DB08904
,153887,DB08904,10048959,160,11450,28,3531,0.004196516,1.762072423,1.171680828,2.74062547,0.017759292,DB0890410048959_,4.0308464,0.566490629,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,153890,DB00338,10000084,46,33628,24,22248,0.393157868,1.26803652,0.757892646,2.172657082,0.563072891,DB0033810000084_,0.574346191,0.237469657,NA,10000084,Abdominal pain lower,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,153896,DB01065,10005483,22,4309,32,3019,0.008261909,0.481722978,0.266151888,0.857112375,0.030556393,DB0106510005483_,3.488181352,-0.730386065,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,melatonin,DB01065
,153916,DB01221,10053762,42,489,48,548,1,0.980587187,0.620478424,1.544725229,1,DB0122110053762_,0,-0.019603716,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ketamine,DB01221
,153954,DB00136,10037844,38,2054,28,1654,0.803035777,1.092855948,0.650165606,1.857260387,0.893394933,DB0013610037844_,0.112726542,0.088794406,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,calcitriol,DB00136
,153955,DB00658,10037844,31,1272,24,1372,0.275391873,1.393033628,0.786561588,2.49491299,0.438720894,DB0065810037844_,0.823891845,0.331483835,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sevelamer,DB00658
,153978,DB00091,10017577,72,5438,12,2658,0.00015631,2.932388508,1.576484313,5.948050759,0.001168542,DB0009110017577_,6.751998045,1.075817281,female,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,153988,DB00688,10071066,64,6426,15,5363,1.14851188342886e-06,3.560435194,2.003479084,6.736346761,1.61825970817087e-05,DB0068810071066_,11.03157415,1.269882783,female,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,mycophenolate mofetil,DB00688
,153989,DB00864,10071066,129,6740,52,8340,8.63863661619088e-13,3.069459445,2.204331703,4.328261784,3.90484201988955e-11,DB0086410071066_,23.9662187,1.12150147,female,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,tacrolimus,DB00864
,153992,DB00688,10075160,23,6467,40,5338,0.004859748,0.474642812,0.270906722,0.813387809,0.020002892,DB0068810075160_,3.911878427,-0.745192733,NA,10075160,Graft versus host disease in gastrointestinal tract,10021428,Immune system disorders,Immun,mycophenolate mofetil,DB00688
,153993,DB00864,10075160,42,6827,52,8340,1,0.986693171,0.640132305,1.51287232,1,DB0086410075160_,0,-0.013396158,NA,10075160,Graft versus host disease in gastrointestinal tract,10021428,Immune system disorders,Immun,tacrolimus,DB00864
,153996,DB01238,10026749,70,5180,56,3446,0.314695932,0.831587036,0.575178171,1.207062195,0.482288341,DB0123810026749_,0.729213125,-0.184419312,NA,10026749,Mania,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,154010,DB00563,10009657,49,46597,52,15296,9.1071668417507e-09,0.309330846,0.204956973,0.46621852,2.06630885140628e-07,DB0056310009657_,15.3923318,-1.173343877,male,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,methotrexate,DB00563
,154051,DB00451,10029354,298,46973,123,15296,0.030803038,0.788937351,0.636830303,0.982260522,0.086501907,DB0045110029354_,2.447588821,-0.237068365,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,levothyroxine,DB00451
,154052,DB13961,10029354,57,9400,39,6375,1,0.991202071,0.647305669,1.531967338,1,DB1396110029354_,0,-0.008836859,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,fish oil,DB13961
,154056,DB01373,10018627,36,22684,23,7358,0.014472047,0.507696276,0.29254473,0.898037015,0.047875875,DB0137310018627_,3.039143561,-0.677871892,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,calcium,DB01373
,154083,DB06643,10062060,58,52363,7,7508,0.851123128,1.188000132,0.541133264,3.086441175,0.926635937,DB0664310062060_,0.076194523,0.172271332,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,denosumab,DB06643
,154096,DB01097,10066901,296,5969,73,1430,0.839475219,0.971413206,0.744290672,1.281296361,0.917794116,DB0109710066901_,0.085782188,-0.029003354,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,154098,DB00813,10019063,46,10526,34,10134,0.263391015,1.302536445,0.81734167,2.094292499,0.425219616,DB0081310019063_,0.8551495,0.264313475,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,fentanyl,DB00813
,154113,DB06403,10054997,70,21401,12,6649,0.067283486,1.812237353,0.974082867,3.676330673,0.156480838,DB0640310054997_,1.854821718,0.594562189,NA,10054997,Infusion site infection,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,154126,DB00363,10007776,20,4608,35,6853,0.585025062,0.849861586,0.464233198,1.515606885,0.732628211,DB0036310007776_,0.311116921,-0.162681783,NA,10007776,Catatonia,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,154158,DB00451,10012239,44,47227,20,15399,0.244321268,0.717343997,0.413825682,1.285167328,0.402884852,DB0045110012239_,0.909104485,-0.33219978,NA,10012239,Delusion,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,154161,DB00451,10033864,33,47238,18,15401,0.101752093,0.597727304,0.326800722,1.12785979,0.213554276,DB0045110033864_,1.543864257,-0.514620642,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,154182,DB08908,10041349,63,10610,13,3266,0.222241834,1.491690633,0.811335451,2.958739709,0.376344969,DB0890810041349_,0.977249086,0.399910129,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,154185,DB00374,10051099,107,17609,21,5703,0.038456369,1.650098612,1.02560561,2.777405174,0.102543816,DB0037410051099_,2.277465101,0.500835051,NA,10051099,Catheter site haemorrhage,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,154195,DB08932,10022687,82,19361,30,6567,0.744015639,0.927106718,0.602873523,1.460857894,0.853713896,DB0893210022687_,0.158159158,-0.075686598,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,154202,DB00404,10035226,75,19817,57,9805,0.01591162,0.651017174,0.454805473,0.936323945,0.051616522,DB0040410035226_,2.963913456,-0.429219256,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,alprazolam,DB00404
,154206,DB01267,10061920,92,2760,167,3548,0.008723653,0.708221056,0.540325672,0.923658957,0.031931657,DB0126710061920_,3.444157379,-0.344999008,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,154212,DB00480,10049848,327,67101,366,67296,0.158758659,0.896040124,0.769207981,1.04344768,0.295829472,DB0048010049848_,1.217972098,-0.109770086,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,154245,DB00776,10037660,31,1874,38,1301,0.025389015,0.566468173,0.338897072,0.940278811,0.074355758,DB0077610037660_,2.598894165,-0.568334382,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,oxcarbazepine,DB00776
,154246,DB00879,10037660,13,1764,44,3668,0.153921193,0.614407424,0.302808006,1.165117199,0.289400468,DB0087910037660_,1.239943846,-0.487097014,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,emtricitabine,DB00879
,154274,DB00019,10047940,102,18910,47,9482,0.66410141,1.088199462,0.762296304,1.573396808,0.795456974,DB0001910047940_,0.228838519,0.08452446,NA,10047940,White blood cell count abnormal,10022891,Investigations,Inv,pegfilgrastim,DB00019
,154276,DB00461,10013700,135,955,17,308,0.000140563,2.559767237,1.510459374,4.597847591,0.0010666,DB0046110013700_,6.84327915,0.939916331,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,nabumetone,DB00461
,154277,DB00878,10013700,67,1119,24,896,0.000727133,2.234486161,1.370215843,3.757751089,0.004224267,DB0087810013700_,5.466909628,0.804011296,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,chlorhexidine,DB00878
,154279,DB00860,10003239,38,1845,16,1480,0.037366783,1.904785432,1.032265394,3.674412392,0.100315176,DB0086010003239_,2.299438286,0.644369368,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisolone,DB00860
,154288,DB00451,10043709,133,47138,33,15386,0.175842119,1.315485747,0.892457433,1.989847331,0.318451846,DB0045110043709_,1.144284005,0.274205987,NA,10043709,Thyroid disorder,10014698,Endocrine disorders,Endo,levothyroxine,DB00451
,154289,DB00480,10043709,71,67357,33,67629,0.000173256,2.160180643,1.410248472,3.371864743,0.001277966,DB0048010043709_,6.6624856,0.770191849,NA,10043709,Thyroid disorder,10014698,Endocrine disorders,Endo,lenalidomide,DB00480
,154292,DB00203,10050584,122,13756,47,8891,0.002546649,1.677685698,1.187780279,2.40441151,0.011829755,DB0020310050584_,4.437137273,0.517415283,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,154293,DB01240,10050584,56,5695,11,1565,0.37094818,1.398924195,0.722948561,2.968775483,0.540636147,DB0124010050584_,0.615008782,0.335703509,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,epoprostenol,DB01240
,154294,DB00051,10013687,44,25687,17,11403,0.679211223,1.148961488,0.643042723,2.14593803,0.8058802,DB0005110013687_,0.215820183,0.138858481,NA,10013687,Drug eruption,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,154309,DB00126,10033557,91,10080,20,5925,1.76390408073834e-05,2.67432799,1.632643748,4.587628153,0.000178702,DB0012610033557_,8.62979127,0.98369813,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,ascorbic acid,DB00126
,154325,DB00051,10047943,63,25668,30,11390,0.736801469,0.931864205,0.593890377,1.492142159,0.848101711,DB0005110047943_,0.164754708,-0.070568178,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,adalimumab,DB00051
,154326,DB00126,10047943,37,10134,24,5921,0.691734987,0.900758932,0.524130878,1.575530186,0.814161162,DB0012610047943_,0.205596945,-0.104517613,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,ascorbic acid,DB00126
,154327,DB00169,10047943,110,38581,72,18103,0.031396679,0.716851412,0.52752214,0.9792926,0.087770455,DB0016910047943_,2.433030339,-0.332886695,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,154331,DB00115,10066901,34,18391,17,10455,0.771063865,1.136984377,0.617456446,2.171229971,0.874688779,DB0011510066901_,0.133887137,0.128379474,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,154334,DB00019,10002855,68,18944,22,9507,0.073918632,1.551142976,0.946286745,2.637079011,0.168046292,DB0001910002855_,1.783515788,0.438992063,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,pegfilgrastim,DB00019
,154335,DB00019,10060933,35,18977,24,9505,0.268627097,0.730415505,0.422037688,1.284305681,0.431066617,DB0001910060933_,0.841492637,-0.314141721,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,154337,DB00184,10013700,51,1243,17,965,0.00259313,2.328210553,1.312470838,4.32901597,0.01200536,DB0018410013700_,4.422402084,0.84509997,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,nicotine,DB00184
,154361,DB00193,10000087,239,19081,68,8634,0.00062173,1.590352275,1.208507303,2.116733143,0.003711177,DB0019310000087_,5.596406209,0.463955548,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,154370,DB01238,10022086,50,5200,33,3469,1,1.010779948,0.636963592,1.623205856,1,DB0123810022086_,0,0.010722259,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,154400,DB01046,10013573,45,840,12,316,0.360126697,1.410401406,0.722089236,2.968528516,0.529962782,DB0104610013573_,0.634948498,0.343874349,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lubiprostone,DB01046
,154424,DB00425,10013538,31,12664,23,7461,0.400801735,0.794094108,0.447880285,1.427269768,0.570682285,DB0042510013538_,0.560922643,-0.230553301,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,zolpidem,DB00425
,154425,DB00537,10013538,62,7495,36,4262,0.916314051,0.979325364,0.638089161,1.523217106,0.962623242,DB0053710013538_,0.038093178,-0.020891348,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,154430,DB01136,10013538,36,9848,25,11090,0.071699432,1.621555117,0.946124269,2.820293542,0.164244156,DB0113610013538_,1.806401199,0.483385637,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,carvedilol,DB01136
,154434,DB01047,10028813,68,719,24,456,0.018647677,1.796163271,1.094597013,3.037861739,0.05847351,DB0104710028813_,2.839181443,0.585652874,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fluocinonide,DB01047
,154439,DB00480,10043224,44,67384,14,67648,6.33495038399765e-05,3.155388023,1.696839142,6.234122534,0.00053923,DB0048010043224_,7.525368681,1.149111475,female,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,154447,DB00820,10043554,33,11882,23,5793,0.200199402,0.699515593,0.398141488,1.248937662,0.349209721,DB0082010043554_,1.052082617,-0.357367193,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,tadalafil,DB00820
,154461,DB01076,10048592,36,25711,30,25553,0.538457961,1.192620162,0.713925576,2.005467879,0.694351845,DB0107610048592_,0.364776466,0.176152703,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,154472,DB00051,10030041,47,25684,9,11411,0.019411324,2.320107979,1.123539403,5.386149688,0.060388998,DB0005110030041_,2.806948335,0.841613727,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,adalimumab,DB00051
,154476,DB00956,10047513,49,5765,20,3447,0.169845024,1.464842875,0.853106644,2.606273725,0.310705811,DB0095610047513_,1.168908759,0.381747984,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,hydrocodone,DB00956
,154536,DB01285,10035664,35,1241,17,592,1,0.982128827,0.53058703,1.885670501,1,DB0128510035664_,0,-0.018032791,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,corticotropin,DB01285
,154550,DB01234,10044055,53,31572,30,32858,0.008047399,1.838596677,1.153202988,2.981309757,0.029929377,DB0123410044055_,3.508914779,0.609002605,NA,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,154551,DB00169,10048762,61,38630,17,18158,0.0674599,1.686632897,0.972067713,3.081389737,0.156794012,DB0016910048762_,1.85282236,0.522734173,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,154553,DB01373,10048762,43,22677,7,7374,0.09913498,1.997358654,0.890374219,5.26481283,0.20953385,DB0137310048762_,1.562869977,0.691825635,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,calcium,DB01373
,154580,DB00758,10024264,34,8266,44,10030,0.820264688,0.937618315,0.580609193,1.502421583,0.904288487,DB0075810024264_,0.100606847,-0.064412326,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,154596,DB00047,10000087,99,9186,60,8458,0.010660359,1.519194961,1.089867239,2.132936962,0.037460901,DB0004710000087_,3.284457539,0.418180564,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,insulin glargine,DB00047
,154600,DB00381,10024378,42,29318,65,22822,0.000575219,0.50299982,0.332688995,0.753153163,0.003469688,DB0038110024378_,5.663690531,-0.687165466,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,amlodipine,DB00381
,154632,DB00421,10036653,38,8865,30,5222,0.257497543,0.746174736,0.44957308,1.248704281,0.418397541,DB0042110036653_,0.871323244,-0.292795475,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,154640,DB00820,10003119,33,11882,19,5797,0.556976027,0.847391375,0.467432213,1.578811653,0.710211239,DB0082010003119_,0.342192834,-0.165592619,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,tadalafil,DB00820
,154641,DB00921,10013663,199,5646,265,4638,4.06538859141383e-07,0.616912012,0.508556598,0.747412064,6.41987017875114e-06,DB0092110013663_,11.95611266,-0.483028872,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,154642,DB00924,10015150,98,10064,27,4224,0.060681367,1.523395849,0.984664619,2.430897423,0.144661572,DB0092410015150_,1.933358249,0.420941954,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,cyclobenzaprine,DB00924
,154664,DB00404,10016288,33,19859,27,9835,0.055119079,0.605291232,0.352731358,1.047187715,0.134541021,DB0040410016288_,2.005886137,-0.502045561,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,alprazolam,DB00404
,154669,DB01175,10016288,31,10693,22,4870,0.136757405,0.641770351,0.35938287,1.164621524,0.265152202,DB0117510016288_,1.327451272,-0.443524748,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,escitalopram,DB01175
,154672,DB00158,10021789,232,16583,110,7994,0.907603298,1.01671743,0.805566836,1.2896576,0.958771936,DB0015810021789_,0.042102046,0.016579232,NA,10021789,Infection,10021881,Infections and infestations,Infec,folic acid,DB00158
,154673,DB00273,10042772,55,8426,13,2180,0.880723738,1.094586626,0.589051055,2.188259634,0.950123172,DB0027310042772_,0.051163648,0.090376782,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,154674,DB00620,10042772,29,4799,33,3099,0.026775943,0.567546746,0.331672792,0.966202157,0.077503101,DB0062010042772_,2.557437333,-0.566432161,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,triamcinolone,DB00620
,154688,DB01118,10043778,7,3056,49,4660,1.30357894185893e-05,0.217871014,0.083145588,0.484392889,0.000137073,DB0111810043778_,8.89499725,-1.523852071,male,10043778,Thyroiditis,10014698,Endocrine disorders,Endo,amiodarone,DB01118
,154705,DB00624,10041349,6,556,46,4350,1,1.0204862,0.354531241,2.410487836,1,DB0062410041349_,0,0.02027918,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,testosterone,DB00624
,154706,DB00776,10041349,32,1873,29,1310,0.358399075,0.771837233,0.449794923,1.329484438,0.528142189,DB0077610041349_,0.638389734,-0.25898159,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,oxcarbazepine,DB00776
,154707,DB01065,10041349,84,4247,60,2991,0.932119201,0.985965113,0.69705524,1.401907313,0.972985711,DB0106510041349_,0.027385882,-0.014134307,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,melatonin,DB01065
,154716,DB00046,10046735,41,5418,17,4675,0.011507345,2.080834623,1.154612064,3.911787273,0.039848569,DB0004610046735_,3.222668779,0.732769074,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,insulin lispro,DB00046
,154721,DB01068,10043607,59,13704,43,6797,0.058009507,0.68053454,0.451143053,1.034025358,0.13970697,DB0106810043607_,1.968208123,-0.384876702,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,clonazepam,DB01068
,154725,DB00230,10047924,77,19597,13,8638,0.000530011,2.610711829,1.439167032,5.125965182,0.00323721,DB0023010047924_,5.733043456,0.959622915,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,154731,DB00641,10016766,47,14077,56,12419,0.138188792,0.740446863,0.491148312,1.111932987,0.267227692,DB0064110016766_,1.319654203,-0.300501407,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,154758,DB01068,10012218,44,13719,32,6808,0.112260511,0.682332883,0.422596684,1.112848028,0.229453151,DB0106810012218_,1.472056406,-0.382237642,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,154763,DB00230,10051076,262,19412,160,8491,0.00114339,0.716258063,0.585144884,0.878958992,0.006154999,DB0023010051076_,5.090490728,-0.333714754,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,154818,DB08906,10003239,56,2137,19,1139,0.109736533,1.570722148,0.913840109,2.813709049,0.225654196,DB0890610003239_,1.488751556,0.451535481,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone furoate,DB08906
,154830,DB01234,10018867,29,31596,48,32840,0.052200087,0.627961505,0.381713676,1.016545393,0.129161186,DB0123410018867_,2.046694153,-0.465276411,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,dexamethasone,DB01234
,154832,DB00563,10029366,48,46598,47,15301,2.51427189805506e-07,0.335355406,0.219444652,0.512695935,4.17351669342451e-06,DB0056310029366_,12.38675155,-1.092564397,male,10029366,Neutrophil count decreased,10022891,Investigations,Inv,methotrexate,DB00563
,154833,DB00059,10035528,19,808,43,1064,0.05123434,0.582011289,0.317733293,1.029496043,0.127356041,DB0005910035528_,2.06076864,-0.541265435,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,pegaspargase,DB00059
,154834,DB00059,10035598,31,796,29,1078,0.184781892,1.447363679,0.836266473,2.511421561,0.329902668,DB0005910035598_,1.108957613,0.369743749,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pegaspargase,DB00059
,154836,DB00541,10043089,24,3110,31,4266,0.891210239,1.061941267,0.595122898,1.873501063,0.954816394,DB0054110043089_,0.046236214,0.060098617,NA,10043089,Tachypnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vincristine,DB00541
,154838,DB01234,10043089,31,31594,53,32835,0.028742392,0.607888224,0.377085577,0.964762726,0.081919996,DB0123410043089_,2.502012168,-0.497764255,NA,10043089,Tachypnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,154870,DB00230,10003553,121,19553,18,8633,1.78370765352067e-06,2.967800412,1.799114949,5.180092116,2.39391144614709e-05,DB0023010003553_,10.63999685,1.087821076,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,154882,DB00188,10047513,52,7834,40,8788,0.07556041,1.458265348,0.945962028,2.263003915,0.170722944,DB0018810047513_,1.767713249,0.377247612,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,bortezomib,DB00188
,154888,DB08932,10037437,40,19403,26,6571,0.015013515,0.521058322,0.309973504,0.88999082,0.049356545,DB0893210037437_,3.0086849,-0.651893301,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,154898,DB01050,10029366,42,18066,18,9353,0.586174278,1.207961787,0.680015841,2.230799155,0.733397953,DB0105010029366_,0.310066814,0.188934466,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,ibuprofen,DB01050
,154901,DB01050,10047942,188,17920,81,9290,0.174933317,1.203200777,0.921328723,1.583257545,0.317374534,DB0105010047942_,1.147672708,0.18498532,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,ibuprofen,DB01050
,154904,DB00480,10061406,25,67403,47,67615,0.012760554,0.533593494,0.314712455,0.884834049,0.043242591,DB0048010061406_,3.140929367,-0.628120978,NA,10061406,Cardiac valve disease,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,154922,DB00115,10005750,207,18218,91,10381,0.039552619,1.296182728,1.006946941,1.679415747,0.104760237,DB0011510005750_,2.256080997,0.259423582,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,154923,DB00126,10005750,119,10052,50,5895,0.054132283,1.395724366,0.993389714,1.986253755,0.132709665,DB0012610005750_,2.019591508,0.333413539,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,ascorbic acid,DB00126
,154924,DB00688,10005750,32,6458,29,5349,0.796817055,0.913966056,0.534755279,1.568057475,0.890036389,DB0068810005750_,0.116492931,-0.089961846,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,mycophenolate mofetil,DB00688
,154942,DB00126,10033318,34,10137,26,5919,0.348031928,0.763592329,0.444346514,1.326470757,0.517575752,DB0012610033318_,0.658599383,-0.269721233,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,ascorbic acid,DB00126
,154947,DB00115,10041349,225,18200,101,10371,0.04881601,1.26944737,0.998131021,1.623703477,0.122799198,DB0011510041349_,2.097204798,0.238581664,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,154951,DB00331,10051118,67,24879,35,20717,0.028095938,1.594025707,1.043501368,2.473448222,0.080446812,DB0033110051118_,2.520159028,0.466262708,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,154954,DB06655,10017885,36,3652,32,2087,0.076142592,0.642982133,0.386900851,1.072801207,0.171720663,DB0665510017885_,1.761886173,-0.441638342,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,liraglutide,DB06655
,154965,DB00316,10022035,42,65432,11,36942,0.021457578,2.155675328,1.090551403,4.643585809,0.065352717,DB0031610022035_,2.727956269,0.768104052,NA,10022035,Initial insomnia,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,154985,DB00199,10047700,122,2588,18,682,0.024218663,1.785792748,1.074443212,3.13686208,0.071740299,DB0019910047700_,2.634702635,0.579862433,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,erythromycin,DB00199
,154986,DB01432,10047700,43,1248,13,657,0.086921412,1.740862398,0.910934768,3.554950593,0.189903526,DB0143210047700_,1.661239092,0.554380621,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cholestyramine,DB01432
,154987,DB00381,10005728,66,29294,52,22835,1,0.989378211,0.67719508,1.452157957,1,DB0038110005728_,0,-0.010678603,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,amlodipine,DB00381
,154988,DB00678,10005728,62,15537,30,10694,0.136298201,1.422451696,0.905139868,2.280591588,0.264525287,DB0067810005728_,1.329818431,0.352381929,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,losartan,DB00678
,154990,DB00264,10015967,54,29553,27,24865,0.025818589,1.68271936,1.041266381,2.779335618,0.075291686,DB0026410015967_,2.586385559,0.520411151,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,metoprolol,DB00264
,155020,DB00993,10009900,41,3208,26,1593,0.360992282,0.783118334,0.465787027,1.33858813,0.530909616,DB0099310009900_,0.633163486,-0.244471465,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,azathioprine,DB00993
,155057,DB01075,10012218,61,19887,49,11048,0.058311885,0.691626894,0.466706243,1.029517987,0.140314726,DB0107510012218_,1.96386734,-0.368708639,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,155066,DB00476,10001497,1186,16071,425,5752,0.976633425,0.998781082,0.889538227,1.123023373,1,DB0047610001497_,0,-0.001219661,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,155071,DB00476,10013911,48,17209,27,6150,0.065701308,0.635340226,0.388157984,1.059986308,0.153637195,DB0047610013911_,1.873161335,-0.453594635,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,155085,DB01273,10042458,71,1969,67,1208,0.015568953,0.650248037,0.455334354,0.929367739,0.050765735,DB0127310042458_,2.980533663,-0.430401393,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,varenicline,DB01273
,155136,DB00203,10047513,111,13767,77,8861,0.652742939,0.927849296,0.686675743,1.259134256,0.786907981,DB0020310047513_,0.239643962,-0.074885956,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,sildenafil,DB00203
,155140,DB06643,10012174,116,52305,62,7453,1.54307938909862e-14,0.266597266,0.194020894,0.369371388,8.85586064245791e-13,DB0664310012174_,27.75252675,-1.322016126,male,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,denosumab,DB06643
,155147,DB00381,10025476,39,29321,19,22868,0.111410979,1.600869247,0.902803905,2.933889209,0.22816031,DB0038110025476_,1.477706784,0.470546761,NA,10025476,Malabsorption,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,155159,DB00273,10043071,64,8417,10,2183,0.149619321,1.65978745,0.844785888,3.632039492,0.283451212,DB0027310043071_,1.260715262,0.506689552,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,topiramate,DB00273
,155160,DB00741,10043071,35,4059,48,3126,0.010239122,0.561616088,0.351641505,0.888967472,0.036238455,DB0074110043071_,3.317634421,-0.57693678,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,hydrocortisone,DB00741
,155170,DB00115,10016100,36,18389,14,10458,0.242490235,1.462377588,0.769321256,2.936530588,0.40069503,DB0011510016100_,0.914554666,0.380063596,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,155172,DB00635,10016100,38,33015,33,23761,0.470683551,0.828756208,0.505938216,1.363913394,0.636923326,DB0063510016100_,0.451105998,-0.187829247,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,155183,DB00193,10006784,100,19220,44,8658,0.92833464,1.023807478,0.7106385,1.496148606,0.970147351,DB0019310006784_,0.030307311,0.023528499,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,155184,DB00924,10006784,61,10101,9,4242,0.001462528,2.846093237,1.403472577,6.525275535,0.007532585,DB0092410006784_,4.888516977,1.04594726,female,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,155200,DB01224,10007617,284,7824,167,5750,0.025721896,1.249780734,1.025475942,1.526925171,0.075080516,DB0122410007617_,2.5891942,0.222968123,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,quetiapine,DB01224
,155240,DB00230,10060800,108,19566,16,8635,5.44536045102035e-06,2.97876599,1.752168084,5.400685894,6.37051347159758e-05,DB0023010060800_,9.661245391,1.091509117,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,pregabalin,DB00230
,155242,DB00448,10017955,26,5119,30,3094,0.018159375,0.523855195,0.297003641,0.918339402,0.05725311,DB0044810017955_,2.860273321,-0.646539979,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,lansoprazole,DB00448
,155244,DB13961,10017955,51,9406,86,6328,1.56650999699569e-07,0.398985083,0.276056421,0.571589398,2.72958006437069e-06,DB1396110017955_,12.81136278,-0.91883125,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,155279,DB01039,10041349,37,2936,28,3023,0.261598412,1.36051026,0.808005909,2.314342591,0.423210603,DB0103910041349_,0.859885345,0.307859821,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,fenofibrate,DB01039
,155298,DB01118,10072268,26,3037,60,4649,0.095521052,0.663374723,0.400856306,1.070274999,0.204044767,DB0111810072268_,1.589415862,-0.410415255,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,amiodarone,DB01118
,155300,DB01592,10008531,70,6206,27,3040,0.328656428,1.269901722,0.802089136,2.064455757,0.49729351,DB0159210008531_,0.698574863,0.238939513,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,155302,DB01592,10022004,41,6235,13,3054,0.192264856,1.544736672,0.809969915,3.14688556,0.339481978,DB0159210022004_,1.080334417,0.434853457,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,155315,DB00588,10033645,50,16474,26,8442,1,0.985463057,0.601345348,1.650514701,1,DB0058810033645_,0,-0.014643639,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,155319,DB00745,10024855,34,2543,16,1067,0.755236745,0.891649727,0.476515126,1.737775114,0.86263543,DB0074510024855_,0.147763122,-0.114681906,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,modafinil,DB00745
,155320,DB00745,10047700,89,2488,22,1061,0.026018092,1.724943206,1.065168553,2.906221,0.075751613,DB0074510047700_,2.580295547,0.545194126,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,modafinil,DB00745
,155325,DB00115,10040979,70,18355,36,10436,0.685981954,1.105551322,0.72888668,1.702919681,0.810449242,DB0011510040979_,0.210166566,0.100344144,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,155330,DB00996,10038678,77,38876,29,22396,0.054805576,1.529602726,0.985864321,2.433184296,0.133996331,DB0099610038678_,2.009942857,0.425008045,NA,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,155345,DB00327,10052904,31,6107,21,4241,1,1.025138282,0.569657509,1.879797122,1,DB0032710052904_,0,0.024827513,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydromorphone,DB00327
,155366,DB00273,10040984,45,8436,6,2187,0.162466265,1.944207397,0.825445264,5.583927163,0.300607193,DB0027310040984_,1.201950873,0.664854386,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,155381,DB01296,10003549,36,1413,55,928,0.000114849,0.43002861,0.272043115,0.672501681,0.000897789,DB0129610003549_,7.015575984,-0.843903538,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,glucosamine,DB01296
,155385,DB13961,10013990,38,9419,16,6398,0.12624275,1.613206904,0.87744673,3.101795834,0.25047484,DB1396110013990_,1.384396805,0.478224064,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,fish oil,DB13961
,155386,DB00175,10022004,40,8091,20,6086,0.151032065,1.504344012,0.857899462,2.719094853,0.285325607,DB0017510022004_,1.254124269,0.408356931,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,155403,DB01296,10046571,41,1408,17,966,0.103354289,1.65433663,0.913047376,3.125045974,0.216062949,DB0129610046571_,1.532185481,0.503400101,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,glucosamine,DB01296
,155407,DB00175,10061623,49,8082,32,6074,0.574778041,1.150770469,0.721362824,1.859274723,0.724415181,DB0017510061623_,0.322390597,0.140431691,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,155411,DB13961,10061623,68,9389,43,6371,0.771291921,1.073079031,0.720823291,1.613013215,0.874777595,DB1396110061623_,0.133785602,0.070532115,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,155420,DB01224,10020751,41,8067,17,5900,0.061192173,1.763829488,0.979081744,3.314808664,0.145627997,DB0122410020751_,1.926699878,0.567487291,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,quetiapine,DB01224
,155422,DB01068,10040753,207,13556,35,6805,3.5438985986081e-11,2.96879372,2.064670986,4.383800152,1.24617223631323e-09,DB0106810040753_,20.50318919,1.088155716,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,clonazepam,DB01068
,155423,DB01224,10040753,48,8060,12,5905,0.000350224,2.930272751,1.531616773,6.066232563,0.002295099,DB0122410040753_,6.076979364,1.075095508,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,quetiapine,DB01224
,155424,DB00193,10044034,42,19278,22,8680,0.589142422,0.859592358,0.501280354,1.512941096,0.735920569,DB0019310044034_,0.306633089,-0.151297004,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,155436,DB00182,10019303,46,5148,17,2835,0.186257781,1.490058126,0.836281084,2.777834785,0.331753815,DB0018210019303_,1.103362107,0.39881513,NA,10019303,Heart rate increased,10022891,Investigations,Inv,amphetamine,DB00182
,155437,DB00182,10024264,41,5153,19,2833,0.589926105,1.186310476,0.671636143,2.168536283,0.736619447,DB0018210024264_,0.305683874,0.170848051,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,155447,DB00334,10041349,78,2771,73,2739,0.742384516,1.056165609,0.754119762,1.480527459,0.852376218,DB0033410041349_,0.15972728,0.054644999,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,olanzapine,DB00334
,155449,DB00715,10070863,198,4645,151,2136,7.2621866654546e-06,0.603018687,0.48234785,0.755082677,8.19431536816802e-05,DB0071510070863_,9.409484799,-0.505807093,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,paroxetine,DB00715
,155452,DB09072,10028810,231,6240,87,2448,0.799624172,1.041616592,0.806773844,1.354864318,0.891684355,DB0907210028810_,0.114643071,0.040773921,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,sodium oxybate,DB09072
,155459,DB00563,10018884,97,46549,58,15290,0.000511052,0.549358441,0.392554388,0.774683171,0.003143326,DB0056310018884_,5.762473709,-0.599004152,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,methotrexate,DB00563
,155464,DB00773,10035528,59,2264,61,2766,0.403681975,1.181633068,0.808205544,1.726532471,0.573355441,DB0077310035528_,0.556249439,0.166897437,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,etoposide,DB00773
,155465,DB01033,10035528,26,1156,32,1272,0.692218225,0.894078727,0.508402136,1.55889776,0.814511093,DB0103310035528_,0.205167232,-0.111961446,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,mercaptopurine,DB01033
,155468,DB00773,10047942,62,2261,76,2751,1,0.992587118,0.694694351,1.413670141,1,DB0077310047942_,0,-0.007440494,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,etoposide,DB00773
,155469,DB00788,10042458,60,9296,27,5034,0.499237096,1.203339762,0.751117872,1.974390764,0.661080456,DB0078810042458_,0.413879727,0.185100826,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,naproxen,DB00788
,155518,DB00706,10035598,8,1067,116,15809,0.853642309,1.021817079,0.429768194,2.088804829,0.928660858,DB0070610035598_,0.074011668,0.021582492,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tamsulosin,DB00706
,155519,DB00736,10035598,52,10539,23,5530,0.543904483,1.186284701,0.712413981,2.033224502,0.699028425,DB0073610035598_,0.358063873,0.170826323,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,155540,DB00398,10017577,25,702,40,1498,0.281569823,1.333559037,0.768816021,2.272881457,0.445498273,DB0039810017577_,0.808561909,0.287851336,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,sorafenib,DB00398
,155541,DB00398,10019211,44,683,64,1474,0.056901914,1.483463805,0.975957718,2.237710866,0.137621163,DB0039810019211_,1.983250565,0.394379762,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sorafenib,DB00398
,155594,DB00005,10009900,52,128030,31,42388,0.010936928,0.555369043,0.349284828,0.896577939,0.038243603,DB0000510009900_,3.263778981,-0.588122444,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,155643,DB00047,10007515,50,9235,74,8444,0.008776086,0.617824536,0.422158749,0.897649272,0.032069988,DB0004710007515_,3.439834626,-0.481550785,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,insulin glargine,DB00047
,155660,DB00421,10062237,44,8859,48,5204,0.003332184,0.538480815,0.348891875,0.829343677,0.014722886,DB0042110062237_,4.218352107,-0.619003411,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,spironolactone,DB00421
,155667,DB00557,10038695,43,5944,25,3042,0.608881103,0.880273739,0.524499346,1.506996286,0.751435067,DB0055710038695_,0.285770477,-0.127522353,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxyzine,DB00557
,155685,DB00563,10051118,106,46540,54,15294,0.010123001,0.645075315,0.460333309,0.913108694,0.035915918,DB0056310051118_,3.326574694,-0.438388202,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,155708,DB00695,10001949,97,27952,60,20468,0.331824932,1.183794402,0.848805898,1.662669059,0.50061807,DB0069510001949_,0.691911803,0.168724874,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,155710,DB00904,10001949,90,22979,42,14414,0.12757548,1.344136117,0.921447914,1.988907662,0.252205287,DB0090410001949_,1.377511893,0.295751514,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,155725,DB01229,10003481,35,5706,15,2694,0.879423366,1.101632066,0.585090781,2.174951467,0.949360756,DB0122910003481_,0.05196641,0.096792777,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,paclitaxel,DB01229
,155745,DB00537,10005191,38,7519,17,4281,0.48279887,1.27268093,0.700145285,2.407671475,0.647065147,DB0053710005191_,0.435308299,0.241125644,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,ciprofloxacin,DB00537
,155751,DB00295,10006002,61,14602,34,9568,0.4643604,1.175555896,0.75992292,1.846151198,0.631487861,DB0029510006002_,0.45967656,0.161741139,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,155756,DB01101,10006002,63,7526,9,3899,4.78930709558975e-05,3.626185983,1.791414581,8.301727886,0.000425869,DB0110110006002_,7.761378289,1.288181402,female,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,capecitabine,DB01101
,155775,DB00196,10007882,41,5042,24,3261,0.798966856,1.104900758,0.650552177,1.915575896,0.891407184,DB0019610007882_,0.114953959,0.099755519,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,fluconazole,DB00196
,155776,DB00537,10007882,53,7504,27,4271,0.726582102,1.117251866,0.68909149,1.850234443,0.840017178,DB0053710007882_,0.174332938,0.110871979,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,155782,DB01190,10008479,35,4899,25,2260,0.096177947,0.645882375,0.374671469,1.128697287,0.204998163,DB0119010008479_,1.584754263,-0.437137874,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,clindamycin,DB01190
,155811,DB01190,10011224,56,4878,34,2251,0.211087802,0.760054631,0.486138454,1.204248037,0.362619625,DB0119010011224_,1.014400858,-0.274364966,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clindamycin,DB01190
,155866,DB00695,10017533,74,27975,24,20504,0.000303037,2.259841573,1.408753836,3.746878925,0.002033529,DB0069510017533_,6.197982627,0.81529471,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,155868,DB00904,10017533,62,23007,18,14438,0.002692915,2.161508708,1.261511458,3.883945762,0.012380961,DB0090410017533_,4.391595426,0.770806454,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,ondansetron,DB00904
,155873,DB00531,10017577,33,7219,17,6499,0.065243301,1.747494714,0.944786219,3.348568134,0.15286537,DB0053110017577_,1.878197676,0.55818317,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,155962,DB01229,10021789,42,5699,21,2688,0.892291627,0.943330846,0.544986962,1.680326406,0.955096839,DB0122910021789_,0.045942542,-0.058338214,NA,10021789,Infection,10021881,Infections and infestations,Infec,paclitaxel,DB01229
,155981,DB00399,10023232,92,6900,42,4956,0.017046533,1.573273734,1.078702699,2.327938532,0.054506189,DB0039910023232_,2.909441021,0.45315863,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,156004,DB00904,10028411,219,22850,81,14375,2.85428971655061e-05,1.700883067,1.311251848,2.224825789,0.000271584,DB0090410028411_,8.211240071,0.531147567,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,156037,DB00537,10029354,76,7481,52,4246,0.30998517,0.829549878,0.574112917,1.206746268,0.477438192,DB0053710029354_,0.739320568,-0.186872041,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,ciprofloxacin,DB00537
,156058,DB00997,10033553,96,5235,7,3507,3.82560637470731e-14,9.186956719,4.284141732,23.4824476,2.06905480574448e-12,DB0099710033553_,26.90392923,2.21778473,female,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,doxorubicin,DB00997
,156071,DB00399,10035528,103,6889,108,4890,0.005884907,0.677001057,0.510394796,0.897476635,0.0233117,DB0039910035528_,3.758799884,-0.390082444,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,zoledronic acid,DB00399
,156075,DB01101,10035528,42,7547,16,3892,0.333312061,1.353695799,0.744130062,2.582716239,0.502357082,DB0110110035528_,0.688444093,0.302838481,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,capecitabine,DB01101
,156147,DB00316,10039722,33,65441,17,36936,0.883092066,1.095642333,0.592911414,2.09754902,0.951117766,DB0031610039722_,0.050117391,0.091340797,NA,10039722,Scoliosis,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,156165,DB00997,10039801,46,5285,53,3461,0.005262394,0.568435712,0.373500153,0.862189705,0.021304826,DB0099710039801_,3.84882165,-0.564867057,NA,10039801,Second primary malignancy,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,doxorubicin,DB00997
,156221,DB01190,10047895,48,4886,33,2252,0.091878292,0.670444248,0.420274693,1.081355114,0.19823689,DB0119010047895_,1.618292551,-0.399814729,NA,10047895,Weight decreased,10022891,Investigations,Inv,clindamycin,DB01190
,156233,DB00316,10048962,61,65413,40,36913,0.469141667,0.860575086,0.568125252,1.316456718,0.635474811,DB0031610048962_,0.453382825,-0.150154409,NA,10048962,Brain oedema,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,156256,DB00399,10050819,41,6951,19,4979,0.148119533,1.545643698,0.875772743,2.823162765,0.281400373,DB0039910050819_,1.267976811,0.435440457,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,zoledronic acid,DB00399
,156278,DB00316,10052897,61,65413,28,36925,0.379844897,1.229825997,0.773952116,1.9986502,0.549958585,DB0031610052897_,0.597912304,0.206872693,NA,10052897,Nerve injury,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,156446,DB00115,10039674,36,18389,18,10454,0.777143082,1.136999288,0.628610893,2.128002071,0.878512755,DB0011510039674_,0.129524852,0.128392589,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,156451,DB09140,10003988,146,3595,45,1753,0.007376329,1.581940885,1.119427798,2.273155946,0.027915455,DB0914010003988_,3.578574785,0.458652502,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,oxygen,DB09140
,156452,DB00404,10005734,49,19843,22,9840,0.800931498,1.104481137,0.654894295,1.919441314,0.892356919,DB0040410005734_,0.113889093,0.099375665,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,alprazolam,DB00404
,156456,DB01104,10005734,54,15409,38,7248,0.072449026,0.668429331,0.432846424,1.041555395,0.165565785,DB0110410005734_,1.798386671,-0.402824601,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,sertraline,DB01104
,156471,DB00193,10013971,106,19214,27,8675,0.00635447,1.772498596,1.151643751,2.816418811,0.024796205,DB0019310013971_,3.697064658,0.572390187,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,156472,DB00331,10013971,109,24837,72,20680,0.134903617,1.260499821,0.926911108,1.722957222,0.26248524,DB0033110013971_,1.337560428,0.231508325,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,156478,DB09140,10019303,92,3649,29,1769,0.049192411,1.537845314,0.999013164,2.431900402,0.123464586,DB0914010019303_,2.091800918,0.43038229,NA,10019303,Heart rate increased,10022891,Investigations,Inv,oxygen,DB09140
,156483,DB00331,10033318,95,24851,56,20696,0.040807325,1.412778498,1.004435297,2.003344114,0.107256692,DB0033110033318_,2.232530329,0.345558332,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,metformin,DB00331
,156486,DB01132,10033371,31,1254,32,1498,0.609803763,1.157184471,0.678744495,1.970554592,0.75209703,DB0113210033371_,0.284889934,0.145989874,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,pioglitazone,DB01132
,156487,DB00455,10040979,31,9370,21,5097,0.468111905,0.803030686,0.44634889,1.471960243,0.634685034,DB0045510040979_,0.454626413,-0.219362352,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,156489,DB00588,10040979,74,16450,44,8424,0.436545472,0.861267551,0.584621783,1.282056632,0.605131753,DB0058810040979_,0.502309072,-0.149350078,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,156493,DB00193,10041569,36,19284,18,8684,0.768628303,0.900651127,0.497906201,1.685809569,0.873150591,DB0019310041569_,0.13564724,-0.104637303,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,156496,DB00404,10041569,32,19860,19,9843,0.552758733,0.834745564,0.458672287,1.559560114,0.706536098,DB0040410041569_,0.347380985,-0.180628314,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,156514,DB00203,10052251,48,13830,14,8924,0.008604545,2.212256591,1.19884476,4.347544009,0.031581437,DB0020310052251_,3.455185755,0.794013076,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,156516,DB00331,10052251,33,24913,19,20733,0.212332547,1.445413654,0.79787292,2.691323802,0.364190235,DB0033110052251_,1.010078923,0.368395546,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,156520,DB00588,10052251,44,16480,18,8450,0.502120109,1.25331748,0.709061185,2.306220382,0.663444193,DB0058810052251_,0.410310539,0.225794019,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,156559,DB05259,10003988,170,11100,37,2691,0.596685601,1.113870061,0.774601303,1.639803708,0.742050851,DB0525910003988_,0.298337506,0.107840493,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,glatiramer,DB05259
,156586,DB05259,10049848,179,11091,57,2671,0.081227467,0.756294527,0.556611993,1.040903833,0.180455899,DB0525910049848_,1.712268855,-0.279324392,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,156587,DB00181,10050584,78,9778,30,5841,0.045415442,1.553098237,1.006011891,2.455191053,0.116360745,DB0018110050584_,2.151060043,0.440251798,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,156606,DB00581,10025482,66,2047,47,2022,0.104600411,1.3869917,0.934666913,2.07224332,0.217921822,DB0058110025482_,1.523618896,0.327137157,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,lactulose,DB00581
,156607,DB00008,10047895,57,1468,53,1623,0.383430791,1.188959451,0.797787,1.774536268,0.553473645,DB0000810047895_,0.591541144,0.173078514,NA,10047895,Weight decreased,10022891,Investigations,Inv,peginterferon alfa-2a,DB00008
,156617,DB00008,10022437,55,1470,77,1599,0.181829605,0.777030308,0.535428009,1.121343504,0.326216037,DB0000810022437_,1.120195426,-0.252275923,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,peginterferon alfa-2a,DB00008
,156620,DB00046,10017955,54,5405,59,4633,0.217648405,0.784550382,0.530998478,1.157132181,0.370727948,DB0004610017955_,0.99228678,-0.242644487,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,insulin lispro,DB00046
,156636,DB00115,10039073,136,18289,21,10451,1.76987613137628e-10,3.700595037,2.324925127,6.174671702,5.55808770767331e-09,DB0011510039073_,19.00801173,1.308493628,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,156642,DB01224,10007515,238,7870,114,5803,0.000155761,1.539346793,1.222911787,1.946853506,0.001165105,DB0122410007515_,6.754944015,0.431358166,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,quetiapine,DB01224
,156645,DB00327,10038669,53,6085,41,4221,0.600162776,0.896710126,0.584074637,1.38540098,0.744646664,DB0032710038669_,0.29484545,-0.109022629,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydromorphone,DB00327
,156654,DB00734,10017600,73,3977,38,4864,1.3084870628315e-05,2.349301527,1.56253814,3.582985358,0.000137519,DB0073410017600_,8.891746127,0.854118061,NA,10017600,Galactorrhoea,10038604,Reproductive system and breast disorders,Repro,risperidone,DB00734
,156656,DB00181,10022000,70,9786,37,5834,0.616439156,1.127879069,0.745764194,1.730703115,0.757579166,DB0018110022000_,0.277627237,0.120338939,NA,10022000,Influenza,10021881,Infections and infestations,Infec,baclofen,DB00181
,156657,DB00722,10022000,247,25156,171,25861,6.72634401859739e-05,1.484905055,1.215926626,1.816794833,0.000567765,DB0072210022000_,7.473803345,0.395350834,NA,10022000,Influenza,10021881,Infections and infestations,Infec,lisinopril,DB00722
,156660,DB01075,10023644,41,19907,17,11080,0.339373757,1.34234738,0.745561834,2.52111205,0.508446476,DB0107510023644_,0.676395327,0.294419857,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,diphenhydramine,DB01075
,156662,DB01075,10039101,113,19835,41,11056,0.018133499,1.536224513,1.064976131,2.254851641,0.057178386,DB0107510039101_,2.861579316,0.429327792,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,156665,DB00641,10063743,33,14091,26,12449,0.69683981,1.121309702,0.650033224,1.953382599,0.817604014,DB0064110063743_,0.20137715,0.114497379,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,simvastatin,DB00641
,156666,DB01075,10063743,40,19908,15,11082,0.207356275,1.484410364,0.801867437,2.894074535,0.358058481,DB0107510063743_,1.027058952,0.395017632,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,diphenhydramine,DB01075
,156672,DB08932,10048561,56,19387,33,6564,0.014184082,0.574569841,0.366866446,0.912903269,0.047077288,DB0893210048561_,3.055964596,-0.55413362,NA,10048561,Stent placement,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,156675,DB00425,10022086,100,12595,34,7450,0.005209855,1.739673909,1.166901697,2.651453213,0.021142663,DB0042510022086_,3.85646232,0.553697687,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,156681,DB11089,10005364,26,10149,35,8372,0.070491701,0.612813928,0.353931663,1.048505626,0.162184284,DB1108910005364_,1.819022034,-0.489693933,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,docusate,DB11089
,156711,DB00927,10055798,44,7453,17,4999,0.065795764,1.735949262,0.970693457,3.244700248,0.153775989,DB0092710055798_,1.872258353,0.551554389,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,famotidine,DB00927
,156732,DB00734,10010305,61,3989,53,4849,0.087886539,1.399012257,0.949852096,2.066264639,0.191661635,DB0073410010305_,1.65202378,0.335766457,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,156735,DB00682,10047943,55,19404,35,16329,0.205058933,1.322388295,0.849692941,2.082825652,0.35519945,DB0068210047943_,1.035075816,0.279439416,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,warfarin,DB00682
,156749,DB00424,10011906,42,1152,33,395,0.000717502,0.436649851,0.266016658,0.721893565,0.004178471,DB0042410011906_,5.477809967,-0.828623662,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,hyoscyamine,DB00424
,156755,DB01013,10033371,50,967,19,588,0.098086781,1.599739075,0.916011371,2.902972695,0.207970561,DB0101310033371_,1.570358742,0.469840538,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,clobetasol propionate,DB01013
,156764,DB01098,10003246,55,8094,31,7178,0.050613919,1.573357115,0.994098015,2.531315497,0.12612693,DB0109810003246_,2.070466495,0.453211626,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,156767,DB01098,10015150,57,8092,41,7168,0.360910127,1.231478434,0.80889695,1.889465005,0.530818493,DB0109810015150_,0.633335138,0.208215426,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,rosuvastatin,DB01098
,156769,DB01098,10016825,47,8102,27,7182,0.07978035,1.543028272,0.940377166,2.579430452,0.178061178,DB0109810016825_,1.725628094,0.433746896,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,rosuvastatin,DB01098
,156771,DB00355,10025082,33,1760,24,1239,0.893016521,0.967962397,0.551950898,1.720745915,0.9554468,DB0035510025082_,0.045576195,-0.032562039,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,aztreonam,DB00355
,156785,DB01240,10037324,67,5684,8,1568,0.022773386,2.310205025,1.104336469,5.580613938,0.068352663,DB0124010037324_,2.683074755,0.837336276,NA,10037324,Pulmonary arterial pressure increased,10022891,Investigations,Inv,epoprostenol,DB01240
,156832,DB00684,10013952,33,2759,18,2330,0.157890872,1.548134618,0.844183992,2.92844194,0.2946407,DB0068410013952_,1.221998633,0.437050734,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tobramycin,DB00684
,156864,DB00215,10020993,41,11062,25,5251,0.355572504,0.778528529,0.461685374,1.337391133,0.525311602,DB0021510020993_,0.643763664,-0.250349642,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,citalopram,DB00215
,156868,DB01136,10063743,28,9856,30,11085,0.895619128,1.049736351,0.603833553,1.819525048,0.95615204,DB0113610063743_,0.044838341,0.048539038,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,carvedilol,DB01136
,156870,DB00213,10067482,49,18846,37,13384,0.826768516,0.940515246,0.600875711,1.483405443,0.908626101,DB0021310067482_,0.0958216,-0.061327419,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,156899,DB00285,10061422,41,10910,23,3695,0.060415795,0.603757542,0.353332999,1.055515811,0.144182784,DB0028510061422_,1.936673454,-0.504582582,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,156916,DB00480,10024774,140,67288,227,67435,6.40048541297628e-06,0.618093294,0.496909715,0.76659775,7.34337665124755e-05,DB0048010024774_,9.519126694,-0.481115871,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,156919,DB08895,10029216,54,28060,7,6639,0.143967231,1.825154063,0.827452071,4.756189978,0.275473441,DB0889510029216_,1.289264056,0.601664402,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,tofacitinib,DB08895
,156920,DB08895,10044565,109,28005,27,6619,0.827057813,0.954151846,0.620762661,1.514460489,0.90884904,DB0889510044565_,0.095576271,-0.046932452,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,156938,DB09072,10029331,40,6431,16,2519,1,0.979242874,0.535144712,1.876563228,1,DB0907210029331_,0,-0.020975583,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,156943,DB00374,10074414,117,17599,39,5685,0.85194002,0.969088692,0.668333052,1.432395145,0.927294854,DB0037410074414_,0.075483691,-0.031399142,NA,10074414,Catheter management,10042613,Surgical and medical procedures,Surg,treprostinil,DB00374
,156944,DB00559,10074414,49,9610,18,3288,0.779619259,0.931389655,0.532109462,1.701294495,0.880016857,DB0055910074414_,0.127814216,-0.071077555,NA,10074414,Catheter management,10042613,Surgical and medical procedures,Surg,bosentan,DB00559
,156945,DB00682,10074414,127,19332,33,16331,4.61515514036325e-11,3.250844989,2.200276606,4.927324003,1.59512627040694e-09,DB0068210074414_,20.25631294,1.178914959,female,10074414,Catheter management,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,156950,DB09053,10048959,51,2234,65,3987,0.079100503,1.400168155,0.947300451,2.060003586,0.176873712,DB0905310048959_,1.732319294,0.33659234,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ibrutinib,DB09053
,157004,DB00005,10058920,57,128025,17,42402,0.788710944,1.110495633,0.636710163,2.036649911,0.885552887,DB0000510058920_,0.121543098,0.104806432,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,157007,DB00788,10022093,73,9283,10,5051,2.5358646580943e-06,3.971728448,2.039086576,8.638447759,3.26101773669318e-05,DB0078810022093_,10.33088613,1.379201377,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,157013,DB01175,10007617,78,10646,22,4870,0.050914131,1.621818424,0.998317517,2.73806458,0.126730865,DB0117510007617_,2.065689614,0.483548004,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,escitalopram,DB01175
,157019,DB01118,10028596,29,3034,45,4664,1,0.990669702,0.597518205,1.61901074,1,DB0111810028596_,0,-0.009374098,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,amiodarone,DB01118
,157025,DB01175,10035598,36,10688,29,4863,0.023019162,0.564870589,0.336291604,0.956228049,0.068952555,DB0117510035598_,2.674336614,-0.57115862,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,157026,DB01233,10035598,38,3383,32,1694,0.040478196,0.5946744,0.360350633,0.987092406,0.106604817,DB0123310035598_,2.238626584,-0.51974125,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoclopramide,DB01233
,157054,DB08910,10029223,30,16714,22,17466,0.214398643,1.424966961,0.794563332,2.593709388,0.366749208,DB0891010029223_,1.003077021,0.354148628,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,157062,DB00773,10029366,61,2262,67,2760,0.589831741,1.110867457,0.768570872,1.603083173,0.736574711,DB0077310029366_,0.305744607,0.105141203,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,etoposide,DB00773
,157093,DB00559,10027175,91,9568,19,3287,0.047948251,1.645250028,0.993802266,2.862198466,0.121248717,DB0055910027175_,2.10991133,0.497892366,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,bosentan,DB00559
,157110,DB00165,10020937,43,2102,22,1344,0.442508711,1.249624992,0.727417928,2.204245364,0.610569105,DB0016510020937_,0.493363797,0.2228435,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,pyridoxine,DB00165
,157115,DB00165,10029331,71,2074,68,1298,0.01628958,0.653558597,0.458446024,0.932264435,0.052573876,DB0016510029331_,2.945535944,-0.425323083,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,pyridoxine,DB00165
,157116,DB00586,10029331,92,7017,33,2772,0.690036268,1.10131322,0.730617753,1.697072433,0.813015717,DB0058610029331_,0.207004838,0.096503304,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,157120,DB00115,10030041,52,18373,9,10463,0.000266507,3.290195914,1.605792879,7.598108734,0.001831887,DB0011510030041_,6.302408444,1.190947111,female,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,cyanocobalamin,DB00115
,157124,DB00338,10030041,66,33608,32,22240,0.179055332,1.364845565,0.881623517,2.152674639,0.322714578,DB0033810030041_,1.130987006,0.311041283,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,omeprazole,DB00338
,157132,DB00165,10033425,67,2078,14,1352,2.64885714698727e-05,3.112845235,1.723996865,6.022281952,0.000253881,DB0016510033425_,8.278644415,1.135537175,female,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,pyridoxine,DB00165
,157143,DB08877,10053762,99,3190,94,3135,0.826822099,1.035036402,0.769050097,1.393795469,0.908665992,DB0887710053762_,0.095777698,0.034436598,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ruxolitinib,DB08877
,157146,DB00410,10013968,100,1505,51,958,0.22835526,1.248020271,0.872839448,1.802719127,0.383853554,DB0041010013968_,0.95749417,0.221558513,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mupirocin,DB00410
,157165,DB00761,10040844,59,15248,19,8606,0.033226298,1.752577827,1.029259518,3.115348932,0.091771711,DB0076110040844_,2.388451184,0.561087748,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,potassium chloride,DB00761
,157187,DB00264,10067973,39,29568,33,24859,1,0.993601445,0.608713357,1.63078495,1,DB0026410067973_,0,-0.006419114,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,metoprolol,DB00264
,157189,DB06643,10067973,66,52355,18,7497,0.019953753,0.525083913,0.307833231,0.940327101,0.061646027,DB0664310067973_,2.786346493,-0.644197196,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,denosumab,DB06643
,157201,DB00853,10051398,26,1795,48,2218,0.12441389,0.669378029,0.396971247,1.10575216,0.247696959,DB0085310051398_,1.395549219,-0.401406312,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,temozolomide,DB00853
,157209,DB00563,10062237,92,46554,57,15291,0.000271701,0.530171801,0.376693528,0.751631844,0.001860533,DB0056310062237_,6.286892405,-0.634554171,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,methotrexate,DB00563
,157227,DB00005,10005619,61,128021,10,42409,0.038546295,2.020595806,1.027349952,4.424375403,0.102736702,DB0000510005619_,2.275585857,0.703392421,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,etanercept,DB00005
,157237,DB01050,10022067,38,18070,15,9356,0.468469581,1.311689082,0.704444677,2.568188727,0.634957095,DB0105010022067_,0.454197849,0.271315682,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,157241,DB00741,10038435,36,4058,21,3153,0.348498946,1.33191937,0.755126206,2.406359864,0.518039476,DB0074110038435_,0.657703832,0.286621038,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,hydrocortisone,DB00741
,157242,DB00028,10033425,156,13302,46,5569,0.03622316,1.419827827,1.014321733,2.021273896,0.097975485,DB0002810033425_,2.323037981,0.350535616,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,human immunoglobulin g,DB00028
,157251,DB00213,10013538,78,18817,31,13390,0.006153718,1.790416817,1.166238855,2.810947012,0.024149073,DB0021310013538_,3.72350929,0.582448452,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,157260,DB00853,10010774,44,1777,69,2197,0.249627167,0.788445246,0.524693485,1.174011374,0.409109825,DB0085310010774_,0.893771638,-0.237692315,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,temozolomide,DB00853
,157267,DB00421,10003445,125,8778,97,5155,0.042385628,0.756815796,0.574520133,0.999392827,0.110444235,DB0042110003445_,2.203244547,-0.27863539,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,157268,DB00524,10003445,37,1540,17,1327,0.037905626,1.875049637,1.024169031,3.568301622,0.101464816,DB0052410003445_,2.288043181,0.628635132,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,metolazone,DB00524
,157275,DB01241,10013968,33,910,40,1031,0.81198557,0.934707173,0.565967298,1.534415579,0.899013951,DB0124110013968_,0.106456727,-0.067521982,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gemfibrozil,DB01241
,157277,DB00390,10013971,102,4043,36,3265,1.23346481347828e-05,2.287825486,1.545814342,3.455500745,0.000130417,DB0039010013971_,8.944774893,0.827601797,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,digoxin,DB00390
,157278,DB00904,10013971,145,22924,70,14386,0.078760777,1.299906492,0.969949361,1.756092427,0.176249533,DB0090410013971_,1.735854488,0.262292332,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,157282,DB00421,10025082,54,8849,18,5234,0.037078999,1.774370427,1.023107491,3.218504831,0.09974634,DB0042110025082_,2.305124911,0.573445671,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,157283,DB00904,10025082,61,23008,18,14438,0.003640713,2.126554185,1.239565091,3.825243597,0.015812315,DB0090410025082_,4.146966184,0.754502916,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,157285,DB00364,10030124,34,2716,17,1383,1,1.018405337,0.551101249,1.951168568,1,DB0036410030124_,0,0.018238009,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,sucralfate,DB00364
,157288,DB00904,10037400,107,22962,30,14426,4.42195463976463e-05,2.240727459,1.481772883,3.482759767,0.000398052,DB0090410037400_,7.828928822,0.806800572,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,157293,DB09140,10038687,51,3690,20,1778,0.523787585,1.228626721,0.717196545,2.182838035,0.681859033,DB0914010038687_,0.382932339,0.205897059,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxygen,DB09140
,157330,DB00188,10000060,67,7819,52,8776,0.052626372,1.446118442,0.990312471,2.121972189,0.129965158,DB0018810000060_,2.040488877,0.36888303,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,157333,DB00572,10000087,55,2847,26,2100,0.069421749,1.560212818,0.958232578,2.601301678,0.160269699,DB0057210000087_,1.830897261,0.444822234,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,atropine,DB00572
,157337,DB01373,10025082,45,22675,20,7361,0.248778738,0.730427379,0.422237098,1.306753406,0.408173848,DB0137310025082_,0.896062096,-0.314125465,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,157354,DB00695,10005287,46,28003,24,20504,0.18509303,1.40338638,0.838742819,2.404690755,0.330267483,DB0069510005287_,1.107852398,0.338888159,NA,10005287,Blood albumin decreased,10022891,Investigations,Inv,furosemide,DB00695
,157367,DB00319,10038540,30,1362,61,1792,0.053680647,0.647156055,0.401116358,1.024210216,0.13188736,DB0031910038540_,2.025807054,-0.435167816,NA,10038540,Renal tubular necrosis,10038359,Renal and urinary disorders,Renal,piperacillin,DB00319
,157389,DB09033,10013573,53,2571,33,1636,1,1.021977708,0.646406393,1.637110715,1,DB0903310013573_,0,0.021739679,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,vedolizumab,DB09033
,157390,DB09033,10013968,82,2542,42,1627,0.262905372,1.249540081,0.846486639,1.868379574,0.424693554,DB0903310013968_,0.85638742,0.222775549,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vedolizumab,DB09033
,157394,DB09033,10016256,116,2508,93,1576,0.094275656,0.783854095,0.587023035,1.048988345,0.202214338,DB0903310016256_,1.598427063,-0.243532379,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,vedolizumab,DB09033
,157417,DB00683,10001497,27,1557,57,1581,0.001812112,0.481093126,0.290926263,0.77789148,0.008972555,DB0068310001497_,4.713584798,-0.731694418,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,midazolam,DB00683
,157418,DB00818,10001497,26,1394,36,1641,0.607076273,0.850235964,0.490290915,1.455912963,0.750017619,DB0081810001497_,0.287658581,-0.162241363,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,propofol,DB00818
,157461,DB00987,10013709,39,2065,84,2844,0.025952467,0.639487852,0.423898858,0.950054373,0.075589849,DB0098710013709_,2.582433281,-0.447087654,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cytarabine,DB00987
,157466,DB00480,10008111,33,67395,55,67607,0.024595196,0.601893225,0.378595099,0.943559189,0.0726061,DB0048010008111_,2.622706337,-0.507675217,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,157594,DB00457,10013573,31,648,22,489,0.887688341,1.063301346,0.587830159,1.95336012,0.953432958,DB0045710013573_,0.047686168,0.061378545,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,prazosin,DB00457
,157603,DB00982,10003988,77,3287,51,2050,0.782838818,0.941628763,0.649494575,1.375182822,0.881806742,DB0098210003988_,0.12578236,-0.060144177,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,isotretinoin,DB00982
,157604,DB00982,10022998,25,3339,34,2067,0.002910123,0.455244636,0.25960025,0.788406404,0.013178154,DB0098210022998_,4.329194838,-0.786920343,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,isotretinoin,DB00982
,157612,DB00294,10013709,67,14304,10,158,1.82741046553438e-08,0.074030514,0.036968315,0.164471091,3.86121254715202e-07,DB0029410013709_,14.76711439,-2.603277919,male,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,etonogestrel,DB00294
,157618,DB00921,10048010,83,5762,110,4793,0.001651634,0.627688558,0.464996954,0.844621129,0.008311929,DB0092110048010_,4.790063516,-0.465711162,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,157646,DB00682,10074903,52,19407,40,16324,0.753447763,1.093513404,0.709807394,1.69576213,0.86130317,DB0068210074903_,0.149308722,0.089395819,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,157663,DB00158,10037423,49,16766,29,8075,0.397419037,0.813813213,0.503561265,1.337104522,0.567125024,DB0015810037423_,0.567175498,-0.206024407,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,157681,DB00916,10020937,54,5269,19,2412,0.375672569,1.300948428,0.756945923,2.329707044,0.545495164,DB0091610020937_,0.606061338,0.263093558,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,metronidazole,DB00916
,157701,DB01012,10005395,66,10566,52,8633,0.85344614,1.037034831,0.709243265,1.523210973,0.92851125,DB0101210005395_,0.074172782,0.036365517,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,cinacalcet,DB01012
,157746,DB01224,10010774,115,7993,83,5834,1,1.01129113,0.754333913,1.360681501,1,DB0122410010774_,0,0.011227861,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,quetiapine,DB01224
,157753,DB01224,10025482,130,7978,70,5847,0.043234495,1.36105191,1.00805313,1.850738742,0.112141087,DB0122410025482_,2.187997496,0.308257864,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,157754,DB05351,10028334,56,2667,19,1112,0.522284775,1.228818035,0.715150137,2.200735972,0.680939225,DB0535110028334_,0.384282221,0.20605276,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,dexlansoprazole,DB05351
,157772,DB11089,10040984,30,10145,20,8387,0.480347932,1.240053786,0.680745593,2.305751854,0.645151907,DB1108910040984_,0.438269475,0.215154754,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,docusate,DB11089
,157811,DB00048,10022086,9,225,55,794,0.158525789,0.577735634,0.247104683,1.202025455,0.295521302,DB0004810022086_,1.219014357,-0.548638895,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,collagenase clostridium histolyticum,DB00048
,157814,DB13867,10022086,41,4509,12,2542,0.044488031,1.926024431,0.990895681,4.033678556,0.114566448,DB1386710022086_,2.166600289,0.655457998,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,157830,DB00620,10001760,61,4767,12,3120,3.10260844423912e-05,3.326608485,1.769843076,6.800521221,0.000292301,DB0062010001760_,8.137725435,1.201953312,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,triamcinolone,DB00620
,157838,DB00741,10028810,59,4035,32,3142,0.110733519,1.435631747,0.91582068,2.287855601,0.227180031,DB0074110028810_,1.482012488,0.361604994,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,hydrocortisone,DB00741
,157844,DB00471,10022061,122,14067,21,5444,0.000239794,2.248239424,1.405524484,3.766802204,0.001676551,DB0047110022061_,6.39101634,0.810147432,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,157846,DB00381,10022093,80,29280,19,22868,3.8635628860672e-07,3.288329505,1.974463252,5.74629235,6.12877190466363e-06,DB0038110022093_,12.00251617,1.190379686,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,157847,DB00471,10022093,76,14113,10,5455,0.000409889,2.9377026,1.511631953,6.376355829,0.002615348,DB0047110022093_,5.946358274,1.077627847,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,157951,DB01202,10018884,41,6673,20,5698,0.039691998,1.750391343,1.000947616,3.157603221,0.105040611,DB0120210018884_,2.253408235,0.559839387,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,levetiracetam,DB01202
,157954,DB00758,10029354,31,8269,47,10027,0.362957465,0.799811157,0.490749596,1.286909817,0.532469155,DB0075810029354_,0.630230308,-0.223379633,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,clopidogrel,DB00758
,157971,DB01050,10013774,51,18057,17,9354,0.124915484,1.554055466,0.882107177,2.872081736,0.248460349,DB0105010013774_,1.392472009,0.440867943,NA,10013774,Dry eye,10015919,Eye disorders,Eye,ibuprofen,DB01050
,157985,DB00175,10039073,66,8065,12,6094,2.39357546004651e-07,4.155483901,2.224440971,8.454036345,3.98954540059115e-06,DB0017510039073_,12.43183327,1.424428884,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,157986,DB00273,10039073,46,8435,11,2182,1,1.081744368,0.550806565,2.319976981,1,DB0027310039073_,0,0.078574894,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,topiramate,DB00273
,157995,DB00997,10048610,68,5263,24,3490,0.007203903,1.878711196,1.161670455,3.135643377,0.027391523,DB0099710048610_,3.597521697,0.630586008,NA,10048610,Cardiotoxicity,10007541,Cardiac disorders,Card,doxorubicin,DB00997
,158005,DB01195,10003658,73,1166,54,690,0.25559268,0.80008464,0.547671051,1.174694833,0.416380217,DB0119510003658_,0.876156454,-0.223037758,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,flecainide,DB01195
,158007,DB06605,10013709,243,13830,206,12827,0.365594373,1.09403204,0.903484589,1.325786389,0.535192453,DB0660510013709_,0.625128871,0.08986999,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,158015,DB00422,10020937,44,3391,14,2935,0.000790513,2.719719925,1.459333601,5.384512816,0.004529401,DB0042210020937_,5.397165564,1.000528906,female,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,methylphenidate,DB00422
,158022,DB00820,10035528,50,11865,35,5781,0.105393549,0.696041176,0.442408972,1.106031616,0.219192899,DB0082010035528_,1.517803121,-0.362346459,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,tadalafil,DB00820
,158023,DB08932,10035528,103,19340,25,6572,0.153303519,1.399989623,0.896402004,2.264896285,0.28861073,DB0893210035528_,1.242676455,0.336464824,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,macitentan,DB08932
,158024,DB00264,10035759,27,29580,30,24862,0.351862619,0.756459081,0.43255483,1.316957079,0.521597662,DB0026410035759_,0.65085875,-0.279106837,NA,10035759,Pneumothorax,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,158028,DB00264,10039203,52,29555,36,24856,0.392966062,1.214784561,0.778865815,1.913516352,0.562967365,DB0026410039203_,0.574533618,0.194566745,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,158078,DB00264,10066152,65,29542,45,24847,0.338811575,1.214879075,0.817734197,1.818932405,0.50789371,DB0026410066152_,0.677483085,0.194644545,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,metoprolol,DB00264
,158089,DB00158,10041349,126,16689,64,8040,0.755941604,0.948456737,0.695721304,1.303910199,0.863147622,DB0015810041349_,0.147169546,-0.052919103,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,158107,DB05676,10017999,41,47088,25,25304,0.6078824,0.881304151,0.523178046,1.512603604,0.750716773,DB0567610017999_,0.286726832,-0.126352479,NA,10017999,Gastrointestinal pain,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,158108,DB00461,10019211,51,1039,16,309,0.881764835,0.947998502,0.522941672,1.807466114,0.950542688,DB0046110019211_,0.050722207,-0.053402357,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,nabumetone,DB00461
,158132,DB00451,10005911,35,47236,17,15402,0.196483865,0.671315009,0.366020702,1.278194033,0.34471889,DB0045110005911_,1.065026007,-0.398516791,NA,10005911,Body temperature increased,10022891,Investigations,Inv,levothyroxine,DB00451
,158137,DB00316,10014418,71,65403,51,36902,0.187950965,0.785507101,0.540357008,1.149000113,0.334005954,DB0031610014418_,1.09659646,-0.241425781,NA,10014418,Electrolyte imbalance,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,158160,DB08907,10016322,44,4209,23,3887,0.027086327,1.766563684,1.041684972,3.071202655,0.078216326,DB0890710016322_,2.548276876,0.569036238,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,canagliflozin,DB08907
,158173,DB00695,10022061,84,27965,9,20519,5.32693317386493e-12,6.847202752,3.439462416,15.4941214,2.14259278462188e-10,DB0069510022061_,22.26383425,1.923840212,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,158174,DB00695,10022093,48,28001,8,20520,9.09766913447739e-06,4.396851441,2.061285828,10.76640515,0.000100055,DB0069510022093_,9.209787248,1.480888703,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,158183,DB01026,10012735,87,1023,54,1014,0.008895935,1.596587446,1.11071887,2.312099628,0.032416827,DB0102610012735_,3.429077636,0.467868505,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ketoconazole,DB01026
,158187,DB01015,10023232,78,9809,40,9341,0.001574005,1.856896181,1.25129733,2.793946564,0.007996272,DB0101510023232_,4.828779864,0.618906374,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfamethoxazole,DB01015
,158215,DB08877,10017577,26,3263,36,3193,0.20220568,0.706769506,0.4087416,1.206673577,0.351635879,DB0887710017577_,1.045159075,-0.347050683,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,ruxolitinib,DB08877
,158221,DB00868,10003239,59,2925,22,1624,0.127856489,1.488861803,0.894824768,2.561798283,0.252608825,DB0086810003239_,1.375913132,0.398011937,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,benzonatate,DB00868
,158223,DB06228,10003239,213,15699,129,15947,3.42542345919632e-06,1.677208398,1.339935233,2.106244938,4.24004029314694e-05,DB0622810003239_,10.06835269,0.517130743,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,rivaroxaban,DB06228
,158224,DB01109,10003549,105,4307,80,4190,0.118325294,1.276807049,0.942327779,1.735414469,0.23870297,DB0110910003549_,1.432535304,0.244362469,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,158226,DB00722,10003997,17,25386,33,25999,0.033402607,0.527600145,0.275551265,0.975079258,0.092148145,DB0072210003997_,2.384357727,-0.639416583,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,lisinopril,DB00722
,158245,DB00868,10037844,80,2904,45,1601,0.92469357,0.980097863,0.668218718,1.453040449,0.967584075,DB0086810037844_,0.032952959,-0.020102852,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,benzonatate,DB00868
,158251,DB00028,10042674,155,13303,52,5563,0.192269395,1.246453019,0.903486262,1.743938612,0.339481978,DB0002810042674_,1.080334417,0.220301933,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,158252,DB00295,10042674,99,14564,61,9541,0.745980583,1.063214549,0.764244964,1.4894081,0.855054056,DB0029510042674_,0.156590589,0.061296912,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,158256,DB01109,10042674,44,4368,17,4253,0.00076967,2.520012147,1.40831943,4.712566703,0.004427348,DB0110910042674_,5.419954496,0.924263722,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,158261,DB00028,10061428,75,13383,30,5585,0.914686348,1.043279063,0.673916921,1.652926393,0.961865977,DB0002810061428_,0.038880155,0.042368699,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,human immunoglobulin g,DB00028
,158295,DB00331,10040943,33,24913,48,20704,0.013766228,0.57136299,0.355160468,0.909018005,0.045925281,DB0033110040943_,3.080739522,-0.559730562,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,158328,DB00230,10037423,33,19641,20,8631,0.295508862,0.725069837,0.403663642,1.334240987,0.461373315,DB0023010037423_,0.773547769,-0.321487301,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,158329,DB00727,10037423,31,3812,40,4133,0.477193917,0.840279916,0.507113816,1.380523261,0.642573878,DB0072710037423_,0.442273483,-0.174020209,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nitroglycerin,DB00727
,158335,DB00230,10061819,68,19606,14,8637,0.007830738,2.139660774,1.191219653,4.121904793,0.029272695,DB0023010061819_,3.531100122,0.7606473,NA,10061819,Disease recurrence,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,158337,DB00338,10061819,35,33639,18,22254,0.403983847,1.28634501,0.708852069,2.413210118,0.573674523,DB0033810061819_,0.555693077,0.251804871,NA,10061819,Disease recurrence,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,158350,DB00190,10041466,37,3260,54,4620,0.915204306,0.971030448,0.619701988,1.506769075,0.962130351,DB0019010041466_,0.038605337,-0.029397454,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,158351,DB00215,10041466,36,11067,16,5260,0.882864464,1.069390166,0.577908874,2.066035917,0.951043643,DB0021510041466_,0.050195326,0.067088548,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,158357,DB00996,10058920,104,38849,30,22395,0.000589295,1.998381287,1.319735881,3.109553365,0.003542511,DB0099610058920_,5.642919579,0.692337496,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,158370,DB00541,10064687,18,3116,32,4265,0.393127576,0.769944314,0.406127802,1.416679315,0.563072891,DB0054110064687_,0.574346191,-0.261437087,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,vincristine,DB00541
,158384,DB01156,10007617,343,13279,216,6112,0.000451842,0.730892719,0.612973431,0.873058081,0.00283927,DB0115610007617_,5.864208152,-0.313488589,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,bupropion,DB01156
,158385,DB00820,10019304,44,11871,19,5797,0.689514859,1.130862072,0.645991654,2.052977112,0.812875364,DB0082010019304_,0.207177486,0.122980237,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,tadalafil,DB00820
,158406,DB08932,10018627,107,19336,58,6539,0.005183254,0.623891978,0.448465664,0.875446182,0.021054217,DB0893210018627_,3.860654394,-0.471778037,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,macitentan,DB08932
,158408,DB00950,10022437,91,4627,23,2033,0.017783491,1.738280871,1.086644558,2.887652609,0.0563587,DB0095010022437_,2.876018664,0.55289662,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,fexofenadine,DB00950
,158411,DB00484,10013774,45,2462,10,1770,0.00028326,3.234385836,1.60148354,7.218930705,0.001926389,DB0048410013774_,6.252107815,1.17383906,female,10013774,Dry eye,10015919,Eye disorders,Eye,brimonidine,DB00484
,158414,DB00484,10030041,131,2376,64,1716,0.011446544,1.478166719,1.080566811,2.039164137,0.039669655,DB0048410030041_,3.227168734,0.390802617,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,brimonidine,DB00484
,158425,DB01307,10000081,38,2486,17,2052,0.040203821,1.844806979,1.012858695,3.496462136,0.106073519,DB0130710000081_,2.243622849,0.612374654,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,insulin detemir,DB01307
,158427,DB09104,10000081,34,1016,24,848,0.593231513,1.182311858,0.674823991,2.101664882,0.739306845,DB0910410000081_,0.302042227,0.167471724,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,magnesium hydroxide,DB09104
,158461,DB01075,10017955,62,19886,45,11052,0.188945363,0.765750814,0.512935592,1.151121132,0.335207579,DB0107510017955_,1.093005299,-0.26689847,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,158467,DB00424,10019211,71,1123,10,418,0.002674064,2.641463606,1.339169634,5.80043134,0.012308513,DB0042410019211_,4.397464122,0.97133316,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,hyoscyamine,DB00424
,158468,DB08900,10019211,35,976,15,422,1,1.008876063,0.530210907,2.010553655,1,DB0890010019211_,0,0.008836903,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,teduglutide,DB08900
,158473,DB01306,10020751,34,4174,25,3841,0.433990943,1.251463385,0.723486251,2.19234252,0.602512493,DB0130610020751_,0.506646879,0.224313574,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,insulin aspart,DB01306
,158480,DB00588,10022004,124,16400,39,8429,0.007675739,1.63411036,1.130794255,2.408563586,0.028820342,DB0058810022004_,3.546673835,0.491098534,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,158493,DB01307,10037660,33,2491,35,2034,0.326130925,0.769929397,0.461942529,1.280651577,0.494682403,DB0130710037660_,0.703839333,-0.26145646,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,insulin detemir,DB01307
,158495,DB08900,10037660,41,970,11,426,0.167843473,1.636422845,0.816244284,3.565288114,0.30793551,DB0890010037660_,1.177864901,0.492512668,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,teduglutide,DB08900
,158540,DB00904,10060933,83,22986,41,14415,0.230029115,1.269507914,0.86265541,1.894516002,0.386000721,DB0090410060933_,0.951916042,0.238629356,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,158594,DB00924,10019303,63,10099,17,4234,0.111087817,1.553673248,0.89665037,2.835766642,0.227718712,DB0092410019303_,1.479644132,0.440621965,NA,10019303,Heart rate increased,10022891,Investigations,Inv,cyclobenzaprine,DB00924
,158600,DB00586,10041349,74,7035,28,2777,0.912299305,1.04321422,0.665386046,1.678193453,0.960594091,DB0058610041349_,0.040203341,0.042306543,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,158607,DB08820,10018964,91,4310,56,3489,0.112199802,1.315411998,0.929747246,1.87510929,0.2293469,DB0882010018964_,1.472519574,0.274149923,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ivacaftor,DB08820
,158663,DB00047,10015090,39,9246,28,8490,0.33009305,1.278950296,0.766361535,2.160070431,0.498735173,DB0004710015090_,0.695680039,0.24603966,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,158664,DB00175,10015090,40,8091,51,6055,0.014100118,0.58698506,0.377513697,0.90703913,0.046866667,DB0017510015090_,3.06044858,-0.532755911,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,158665,DB00575,10015090,34,5210,27,3802,0.795189546,0.918954297,0.537171478,1.586472488,0.889098203,DB0057510015090_,0.117547584,-0.084518889,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonidine,DB00575
,158666,DB00727,10015090,38,3805,24,4149,0.040683615,1.726346244,1.00695434,3.014750762,0.107001081,DB0072710015090_,2.234916338,0.546007178,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nitroglycerin,DB00727
,158673,DB00555,10044223,52,6995,20,3466,0.38022022,1.288309863,0.754625182,2.281970634,0.550337744,DB0055510044223_,0.59722311,0.253331176,NA,10044223,Toxic epidermal necrolysis,10040785,Skin and subcutaneous tissue disorders,Skin,lamotrigine,DB00555
,158677,DB08880,10016322,63,3275,17,792,0.670003175,0.896206173,0.5145118,1.643174534,0.799758272,DB0888010016322_,0.223445757,-0.109584788,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,teriflunomide,DB08880
,158678,DB08880,10012378,97,3241,22,787,0.906510811,1.07059768,0.663500254,1.798877659,0.958224861,DB0888010012378_,0.042672809,0.068217072,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,teriflunomide,DB08880
,158697,DB01225,10000059,34,5010,31,4609,1,1.008988048,0.600664126,1.70067215,1,DB0122510000059_,0,0.008947896,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,158698,DB01225,10022437,49,4995,39,4601,0.521587439,1.157287946,0.742915985,1.813691689,0.680359577,DB0122510022437_,0.385133831,0.146079291,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,enoxaparin,DB01225
,158704,DB00668,10016825,48,10043,25,4278,0.44210384,0.817895421,0.493651352,1.386154529,0.610202658,DB0066810016825_,0.49396415,-0.201020798,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,epinephrine,DB00668
,158707,DB01015,10016825,40,9847,24,9357,0.079800509,1.5836867,0.930855147,2.748724418,0.178083489,DB0101510016825_,1.7255028,0.459755483,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,sulfamethoxazole,DB01015
,158717,DB01234,10017944,144,31481,110,32778,0.016702995,1.363012106,1.055505046,1.764151471,0.053642646,DB0123410017944_,2.925410897,0.309697035,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,158721,DB00471,10043528,67,14122,13,5452,0.023581975,1.989670707,1.087276561,3.932911475,0.07025054,DB0047110043528_,2.655687277,0.687969151,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,158727,DB01097,10053762,143,6122,34,1469,1,1.009218932,0.68688198,1.520168533,1,DB0109710053762_,0,0.009176697,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,leflunomide,DB01097
,158732,DB00557,10015090,33,5954,20,3047,0.562164185,0.844425205,0.469512763,1.555753638,0.714426611,DB0055710015090_,0.336275001,-0.169099114,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxyzine,DB00557
,158738,DB00682,10017822,23,19436,39,16325,0.007159963,0.495362289,0.282322648,0.850678112,0.027273332,DB0068210017822_,3.601845901,-0.702465888,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,warfarin,DB00682
,158749,DB01075,10014625,39,19909,31,11066,0.136176968,0.69930553,0.424917098,1.159849941,0.264358316,DB0107510014625_,1.33044984,-0.357667537,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,158753,DB01075,10020993,32,19916,26,11071,0.170000796,0.684204428,0.394795419,1.195942341,0.310893405,DB0107510020993_,1.168305174,-0.379498535,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,diphenhydramine,DB01075
,158760,DB09038,10013573,76,2172,100,2441,0.318090561,0.854153781,0.621697054,1.169585551,0.486091125,DB0903810013573_,0.721359173,-0.157644031,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,empagliflozin,DB09038
,158761,DB09038,10028813,128,2120,103,2438,0.008413397,1.429006147,1.086341897,1.883374956,0.03100759,DB0903810028813_,3.473523269,0.3569792,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,empagliflozin,DB09038
,158762,DB09038,10033371,35,2213,32,2509,0.390991943,1.239984582,0.742837588,2.076400655,0.560840163,DB0903810033371_,0.578319328,0.215098945,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,empagliflozin,DB09038
,158764,DB00678,10039073,109,15490,22,10702,5.50050482801369e-09,3.422919261,2.148874265,5.689955398,1.30842325252796e-07,DB0067810039073_,15.84927286,1.230493772,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,158773,DB00678,10062352,33,15566,20,10704,0.67790015,1.134657086,0.631679551,2.08777493,0.804780398,DB0067810062352_,0.217185837,0.126330479,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,losartan,DB00678
,158812,DB01018,10061422,14,398,49,730,0.040449363,0.524304651,0.263888972,0.979646514,0.106555573,DB0101810061422_,2.239088621,-0.645682369,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,guanfacine,DB01018
,158813,DB01255,10061422,24,2109,53,1525,3.44899353706154e-06,0.327534864,0.192461581,0.542721679,4.26821069311029e-05,DB0125510061422_,10.06173077,-1.116160774,male,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,lisdexamfetamine,DB01255
,158848,DB00112,10013990,34,5899,16,4075,0.24860434,1.467884578,0.787187336,2.851958734,0.40797018,DB0011210013990_,0.896561196,0.383822302,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,bevacizumab,DB00112
,158853,DB00019,10047895,60,18952,42,9487,0.114037414,0.715098912,0.473754074,1.088325681,0.232240985,DB0001910047895_,1.459979716,-0.335334407,NA,10047895,Weight decreased,10022891,Investigations,Inv,pegfilgrastim,DB00019
,158854,DB00019,10053762,1467,17545,765,8764,0.361982268,0.957905886,0.873807665,1.050681452,0.53171108,DB0001910053762_,0.631655021,-0.043005746,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,158869,DB00950,10001760,65,4653,13,2043,0.008762237,2.195144742,1.195011325,4.35148132,0.032032739,DB0095010001760_,3.440996814,0.786247986,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,fexofenadine,DB00950
,158870,DB01248,10001760,71,2629,6,1368,1.28450642273506e-07,6.156268912,2.682706055,17.37820167,2.28284322661197e-06,DB0124810001760_,12.99008886,1.817470898,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,docetaxel,DB01248
,158890,DB00950,10035664,175,4543,98,1958,0.043929414,0.769636454,0.594058635,1.001772315,0.11346022,DB0095010035664_,2.176302991,-0.261837013,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,fexofenadine,DB00950
,158894,DB00999,10043882,59,21371,38,12201,0.597445181,0.886425525,0.579442926,1.370694657,0.742586432,DB0099910043882_,0.297616008,-0.120558167,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,hydrochlorothiazide,DB00999
,158918,DB00950,10061428,77,4641,36,2020,0.757038477,0.93096539,0.616627933,1.42912554,0.864092597,DB0095010061428_,0.146075343,-0.071533178,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,fexofenadine,DB00950
,158961,DB00019,10061818,93,18919,47,9482,1,0.991713041,0.690430921,1.441387485,1,DB0001910061818_,0,-0.008321487,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,158967,DB01118,10021114,58,3005,36,4673,1.58076826302271e-05,2.505106469,1.620404385,3.919682125,0.000162085,DB0111810021114_,8.727389572,0.918331236,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,amiodarone,DB01118
,158975,DB00377,10053762,268,851,208,515,0.022126467,0.779858148,0.627729703,0.96945375,0.066922983,DB0037710053762_,2.704212827,-0.248643237,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,palonosetron,DB00377
,159000,DB01248,10013709,50,2650,33,1341,0.242569007,0.766800831,0.481743995,1.234959762,0.400762208,DB0124810013709_,0.914387026,-0.265528184,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,159021,DB00158,10013950,93,16722,49,8055,0.653387073,0.914254333,0.639390723,1.321391048,0.787503919,DB0015810013950_,0.238886932,-0.089646483,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,159024,DB01202,10013950,38,6676,34,5684,0.905732553,0.951553449,0.582355623,1.560474079,0.957861963,DB0120210013950_,0.0430516,-0.04965942,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,levetiracetam,DB01202
,159030,DB00958,10021789,59,4535,43,2542,0.212481416,0.769145576,0.508780515,1.171000501,0.364394469,DB0095810021789_,1.009518293,-0.262475021,NA,10021789,Infection,10021881,Infections and infestations,Infec,carboplatin,DB00958
,159031,DB00158,10028372,122,16693,53,8051,0.571181041,1.110186789,0.79694852,1.564872626,0.721482994,DB0015810028372_,0.326446471,0.10452828,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,159040,DB00112,10068319,48,5885,17,4074,0.015981297,1.9545118,1.1020684,3.630543419,0.051785443,DB0011210068319_,2.960646193,0.670140443,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bevacizumab,DB00112
,159070,DB00947,10016256,725,2447,12,56,0.380599989,1.382501627,0.727505466,2.849819593,0.550672687,DB0094710016256_,0.596614681,0.323894631,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fulvestrant,DB00947
,159073,DB00281,10019303,55,11403,18,5653,0.135659349,1.5147476,0.874925595,2.743789614,0.263653022,DB0028110019303_,1.333121351,0.415248824,NA,10019303,Heart rate increased,10022891,Investigations,Inv,lidocaine,DB00281
,159082,DB09153,10019303,44,7755,32,5667,1,1.004786956,0.622021272,1.639351837,1,DB0915310019303_,0,0.004775535,NA,10019303,Heart rate increased,10022891,Investigations,Inv,sodium chloride,DB09153
,159103,DB00661,10002034,39,3489,20,1575,0.671964806,0.880296466,0.499199694,1.598429581,0.800901423,DB0066110002034_,0.222017406,-0.127496535,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,verapamil,DB00661
,159109,DB00661,10011224,52,3476,12,1583,0.030057683,1.973210806,1.035867074,4.073487594,0.084825661,DB0066110011224_,2.467157171,0.679662067,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,verapamil,DB00661
,159116,DB00661,10040753,48,3480,11,1584,0.046539969,1.985977637,1.013652744,4.252422825,0.118577335,DB0066110040753_,2.132189919,0.686111305,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,verapamil,DB00661
,159118,DB00471,10043554,37,14152,25,5440,0.032872246,0.568939071,0.333051695,0.986994045,0.091014587,DB0047110043554_,2.396735493,-0.563981932,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,montelukast,DB00471
,159122,DB00588,10047942,160,16364,85,8383,0.786444239,0.964322763,0.735645207,1.271477305,0.88414144,DB0058810047942_,0.12313823,-0.036329224,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,159142,DB01062,10002034,59,4427,24,1721,0.902079078,0.955683798,0.583250085,1.611927899,0.957195726,DB0106210002034_,0.043747388,-0.045328176,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,oxybutynin,DB01062
,159179,DB00741,10016825,38,4056,17,3157,0.057099805,1.739712292,0.956357995,3.293611679,0.137979165,DB0074110016825_,1.980652587,0.55371975,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,hydrocortisone,DB00741
,159193,DB01075,10040872,34,19914,18,11079,1,1.050870356,0.576778977,1.977398481,1,DB0107510040872_,0,0.049618731,NA,10040872,Skin infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,159197,DB01234,10046555,29,31596,55,32833,0.008530699,0.547923523,0.336792048,0.874574119,0.031358564,DB0123410046555_,3.462267861,-0.601619558,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,dexamethasone,DB01234
,159235,DB01373,10061246,60,22660,9,7372,0.024783156,2.168693671,1.068910828,4.974257462,0.073021493,DB0137310061246_,2.617001457,0.774124991,NA,10061246,Intervertebral disc degeneration,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,159243,DB00958,10019211,101,4493,37,2548,0.024914689,1.547953215,1.048787699,2.328977106,0.073294078,DB0095810019211_,2.613275459,0.436933552,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,carboplatin,DB00958
,159249,DB00112,10050819,35,5898,23,4068,0.894218185,1.049583186,0.6018691,1.863588516,0.955876492,DB0011210050819_,0.045126567,0.04839312,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bevacizumab,DB00112
,159252,DB00541,10000060,28,3106,39,4258,1,0.984233623,0.581917652,1.644945411,1,DB0054110000060_,0,-0.015891988,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,vincristine,DB00541
,159273,DB01015,10061818,69,9818,80,9301,0.249334899,0.817092494,0.582647474,1.143394034,0.408754659,DB0101510061818_,0.894640158,-0.202002979,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,159286,DB00264,10012373,53,29554,55,24837,0.288307248,0.809840297,0.544479527,1.203532704,0.453304061,DB0026410012373_,0.791192161,-0.210918215,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,159291,DB00177,10017577,62,4738,30,2820,0.386631163,1.229984624,0.781102237,1.975763869,0.556748028,DB0017710017577_,0.585642515,0.207001668,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,159298,DB01076,10041466,74,25673,49,25534,0.029953425,1.502007932,1.032494992,2.202107835,0.084608649,DB0107610041466_,2.469718779,0.406802834,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,159300,DB11089,10061024,47,10128,62,8345,0.015703316,0.624634082,0.417739063,0.928548204,0.051106502,DB1108910061024_,2.973843539,-0.47058927,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,docusate,DB11089
,159327,DB00482,10001760,109,8150,10,3061,4.2139757000849e-07,4.093697512,2.139270686,8.788687687,6.62862664732087e-06,DB0048210001760_,11.92411292,1.409448599,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,celecoxib,DB00482
,159387,DB01065,10021143,35,4296,31,3020,0.380242867,0.793718834,0.474220071,1.334253552,0.550337744,DB0106510021143_,0.59722311,-0.231025994,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,melatonin,DB01065
,159392,DB00425,10029148,37,12658,20,7464,0.785679555,1.090889965,0.616436053,1.985210226,0.883734037,DB0042510029148_,0.123599125,0.086993844,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,zolpidem,DB00425
,159395,DB00924,10029148,38,10124,21,4230,0.31744376,0.756054348,0.431983549,1.357802567,0.48527199,DB0092410029148_,0.723045742,-0.279642016,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,cyclobenzaprine,DB00924
,159404,DB00472,10048393,85,10674,22,4290,0.068093955,1.552841782,0.960939227,2.610723351,0.157862904,DB0047210048393_,1.846028321,0.44008666,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,159425,DB00624,10003549,11,551,140,4256,0.118458688,0.606948298,0.294289367,1.129107238,0.238892208,DB0062410003549_,1.43174284,-0.499311668,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,testosterone,DB00624
,159436,DB00624,10010264,12,550,50,4346,0.065268794,1.896020314,0.913250187,3.638863457,0.152904658,DB0062410010264_,1.877940703,0.639757118,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,testosterone,DB00624
,159450,DB00745,10017577,82,2495,31,1052,0.675844052,1.115278574,0.724390552,1.75622256,0.803554995,DB0074510017577_,0.218709652,0.109104216,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,modafinil,DB00745
,159451,DB00370,10019063,46,4495,63,3600,0.00641514,0.584824544,0.389922317,0.87136392,0.024971781,DB0037010019063_,3.690008856,-0.536443402,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,mirtazapine,DB00370
,159457,DB01068,10019196,58,13705,23,6817,0.408632851,1.254285162,0.761038849,2.132645345,0.578043456,DB0106810019196_,0.548106229,0.226565818,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,159460,DB06218,10019211,60,1634,37,1399,0.146978345,1.388255869,0.900412495,2.165454521,0.279749483,DB0621810019211_,1.273860779,0.328048189,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lacosamide,DB06218
,159462,DB00745,10020937,55,2522,13,1070,0.060419175,1.794721795,0.962999978,3.59626892,0.144184303,DB0074510020937_,1.936662918,0.584850021,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,modafinil,DB00745
,159464,DB00370,10022437,100,4441,66,3597,0.207799377,1.227169924,0.887440887,1.706454443,0.35863471,DB0037010022437_,1.02545093,0.204710644,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,mirtazapine,DB00370
,159474,DB00745,10028334,52,2525,13,1070,0.099787819,1.694832132,0.905359993,3.40778303,0.210473666,DB0074510028334_,1.558394736,0.527583699,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,modafinil,DB00745
,159476,DB00370,10028411,38,4503,24,3639,0.371530143,1.279496792,0.746320393,2.234103927,0.541187391,DB0037010028411_,0.613989681,0.246466869,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,mirtazapine,DB00370
,159484,DB00624,10033425,9,553,59,4337,0.564803295,1.196293281,0.518538149,2.445946844,0.716495559,DB0062410033425_,0.33338323,0.179227844,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,testosterone,DB00624
,159486,DB00745,10033775,46,2531,15,1068,0.479505852,1.29391374,0.705749651,2.506373462,0.644498431,DB0074510033775_,0.439282891,0.257671532,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,modafinil,DB00745
,159487,DB01224,10033775,68,8040,25,5892,0.002978517,1.993208564,1.241976894,3.295026286,0.013430022,DB0122410033775_,4.310262635,0.689745684,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,159489,DB06218,10041349,42,1652,41,1395,0.57700977,0.865068568,0.545513334,1.37271036,0.726231208,DB0621810041349_,0.319886846,-0.144946505,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,lacosamide,DB06218
,159497,DB06218,10044565,41,1653,32,1404,0.812337353,1.088252913,0.664723003,1.7957247,0.899071824,DB0621810044565_,0.106392355,0.084573579,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,lacosamide,DB06218
,159552,DB00158,10049848,92,16723,48,8056,0.651813934,0.92332411,0.643778503,1.33909651,0.786166625,DB0015810049848_,0.240586517,-0.079774958,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,159574,DB01202,10043607,35,6679,29,5689,1,1.028004884,0.609583,1.745901471,1,DB0120210043607_,0,0.027619918,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,levetiracetam,DB01202
,159587,DB00575,10040047,52,5192,31,3798,0.434685904,1.227021349,0.770166521,1.984730312,0.603179041,DB0057510040047_,0.505541209,0.204589565,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,clonidine,DB00575
,159590,DB00531,10024264,21,7231,36,6480,0.022993878,0.522778501,0.28966284,0.921052253,0.068894475,DB0053110024264_,2.675179296,-0.64859742,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,159601,DB00316,10030973,40,65434,18,36935,0.494853236,1.254393515,0.702613104,2.324846102,0.657228907,DB0031610030973_,0.419722909,0.2266522,NA,10030973,Oral discomfort,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,159610,DB00544,10061428,39,2396,75,2578,0.003213599,0.559563592,0.368364381,0.838321162,0.014305947,DB0054410061428_,4.247079972,-0.580598099,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,fluorouracil,DB00544
,159646,DB00656,10007617,210,11803,148,6471,0.022177005,0.777951926,0.625902907,0.968853512,0.067033415,DB0065610007617_,2.702564059,-0.251090548,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,trazodone,DB00656
,159647,DB00734,10007617,56,3994,22,4880,2.93032024396474e-06,3.109743375,1.864781376,5.358677957,3.71108010660627e-05,DB0073410007617_,10.2016025,1.134540207,female,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,risperidone,DB00734
,159657,DB00252,10033371,50,2182,17,1891,0.000726389,2.548292667,1.439001388,4.730644326,0.004220576,DB0025210033371_,5.46778363,0.935423592,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,phenytoin,DB00252
,159685,DB00316,10067967,47,65427,27,36926,1,0.982439752,0.599323127,1.640757972,1,DB0031610067967_,0,-0.017716258,NA,10067967,Brain injury,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,159698,DB01050,10012601,30,18078,23,9348,0.190948312,0.674456046,0.378562487,1.216618475,0.337761659,DB0105010012601_,1.085414784,-0.39384877,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,ibuprofen,DB01050
,159719,DB01101,10046571,65,7524,13,3895,0.001050797,2.588201702,1.410728853,5.124933601,0.005742246,DB0110110046571_,5.159904864,0.950963311,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,capecitabine,DB01101
,159721,DB00126,10015150,119,10052,43,5902,0.006730516,1.624848325,1.135679936,2.363397583,0.025966773,DB0012610015150_,3.650937512,0.485414473,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,ascorbic acid,DB00126
,159730,DB01076,10050528,13,25734,38,25545,0.000391486,0.339581466,0.165943028,0.651894389,0.002518717,DB0107610050528_,5.984005645,-1.080041401,male,10050528,Ejection fraction decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,159742,DB00531,10020983,80,7172,113,6403,0.001760449,0.632082023,0.46764299,0.85095715,0.008753952,DB0053110020983_,4.738249995,-0.45873611,NA,10020983,Hypogammaglobulinaemia,10021428,Immune system disorders,Immun,cyclophosphamide,DB00531
,159759,DB00678,10012378,226,15373,87,10637,1.85934969352645e-06,1.797377114,1.395780113,2.332004669,2.48591081863391e-05,DB0067810012378_,10.60228635,0.586328443,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,losartan,DB00678
,159767,DB00678,10028391,87,15512,55,10669,0.668930041,1.087972886,0.766683398,1.555335165,0.798928849,DB0067810028391_,0.224483387,0.084316227,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,159768,DB00678,10029410,40,15559,17,10707,0.105559727,1.619157006,0.896785198,3.047673541,0.219460367,DB0067810029410_,1.516583625,0.481905647,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,159769,DB00451,10030216,42,47229,9,15410,0.328369644,1.522605375,0.730360029,3.558442776,0.496945395,DB0045110030216_,0.699275129,0.42042293,NA,10030216,Oesophagitis,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,159773,DB00678,10031161,76,15523,22,10702,0.000179172,2.381575475,1.464442172,4.023958661,0.001313861,DB0067810031161_,6.634785363,0.867762233,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,159777,DB00451,10039674,75,47196,10,15409,0.005147978,2.448762575,1.260045573,5.315582965,0.020937215,DB0045110039674_,3.866227086,0.895582826,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,159779,DB00678,10040844,49,15550,43,10681,0.244121239,0.782740722,0.508616107,1.20850715,0.402643414,DB0067810040844_,0.909703938,-0.244953772,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,159781,DB00678,10042609,57,15542,28,10696,0.15176908,1.400959697,0.87579717,2.289380321,0.286407797,DB0067810042609_,1.25033862,0.337157499,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,losartan,DB00678
,159782,DB00678,10043071,67,15532,40,10684,0.492282322,1.152139449,0.766806836,1.751174344,0.655188275,DB0067810043071_,0.422832643,0.141620604,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,losartan,DB00678
,159828,DB00410,10013709,53,1552,37,972,0.659752279,0.897155853,0.573720712,1.415828398,0.792178916,DB0041010013709_,0.232968009,-0.108525682,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,mupirocin,DB00410
,159834,DB00410,10020937,40,1565,12,997,0.021020214,2.122982981,1.085432192,4.4677809,0.064302162,DB0041010020937_,2.744162022,0.752822166,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,mupirocin,DB00410
,159838,DB00410,10022437,33,1572,18,991,0.665643733,1.155720758,0.628150831,2.192637597,0.79663277,DB0041010022437_,0.227361472,0.144724182,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,mupirocin,DB00410
,159843,DB00230,10023230,52,19622,15,8636,0.183540643,1.525737305,0.845303526,2.919701876,0.328350514,DB0023010023230_,1.113673602,0.422477772,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,159852,DB00213,10029216,72,18823,25,13396,0.001810167,2.049590861,1.28361848,3.374262875,0.008963874,DB0021310029216_,4.714552755,0.717640193,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,159853,DB00230,10029216,166,19508,39,8612,0.000239913,1.878997848,1.317610229,2.7388055,0.001677155,DB0023010029216_,6.390656389,0.630738575,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,159854,DB00331,10029216,80,24866,28,20724,3.95021501179937e-05,2.381114739,1.530439208,3.806324423,0.000360588,DB0033110029216_,7.927773688,0.867568756,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,metformin,DB00331
,159866,DB00316,10040026,67,65407,30,36923,0.341150507,1.260772899,0.808043454,2.009576643,0.510308507,DB0031610040026_,0.672739821,0.231724945,NA,10040026,Sensory disturbance,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,159869,DB00451,10040026,48,47223,8,15411,0.086681097,1.957950287,0.917938593,4.794173838,0.189520266,DB0045110040026_,1.663259317,0.671898154,NA,10040026,Sensory disturbance,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,159875,DB00115,10074903,93,18332,29,10443,0.00442226,1.826803377,1.191826311,2.877750714,0.018517468,DB0011510074903_,3.98904079,0.602567651,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,159910,DB06589,10013968,42,1988,84,2569,0.022609759,0.646185971,0.433040224,0.95154967,0.06798576,DB0658910013968_,2.688457004,-0.436667937,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pazopanib,DB06589
,159932,DB00706,10038428,7,1068,76,15849,0.367956084,1.366792833,0.530246541,2.965369811,0.537666391,DB0070610038428_,0.620517003,0.312466997,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,tamsulosin,DB00706
,159959,DB01390,10011906,81,1328,106,1411,0.174269915,0.811969333,0.594366885,1.105895719,0.316521025,DB0139010011906_,1.150365611,-0.208292706,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sodium bicarbonate,DB01390
,159970,DB08932,10018092,62,19381,18,6579,0.608877491,1.169227792,0.682129857,2.101888761,0.751435067,DB0893210018092_,0.285770477,0.156343524,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,159973,DB08932,10024855,320,19123,112,6485,0.780382851,0.968915097,0.777447034,1.214848745,0.880415616,DB0893210024855_,0.127361192,-0.031578291,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,159977,DB08932,10036653,205,19238,56,6541,0.153122707,1.244638963,0.920739249,1.706359876,0.288352942,DB0893210036653_,1.243570058,0.218845498,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,160000,DB00641,10040753,200,13924,60,12415,1.80178576886549e-15,2.971772102,2.214420003,4.039415233,1.1737283503006e-13,DB0064110040753_,29.7734209,1.089158442,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,simvastatin,DB00641
,160004,DB11089,10040753,109,10066,34,8373,1.15072552508851e-07,2.666470109,1.797382872,4.047739995,2.06181461669744e-06,DB1108910040753_,13.09192408,0.980755541,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,docusate,DB11089
,160005,DB00338,10046306,292,33382,107,22165,5.97377260795599e-08,1.811961787,1.446101297,2.284402953,1.13372283754602e-06,DB0033810046306_,13.69000379,0.594410118,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,160006,DB00497,10046306,108,19159,47,16328,9.379421719214e-05,1.958260617,1.377155496,2.822168576,0.000755427,DB0049710046306_,7.188227459,0.672056639,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,oxycodone,DB00497
,160010,DB00588,10039203,62,16462,20,8448,0.079167899,1.590836378,0.947063114,2.782779887,0.177002359,DB0058810039203_,1.73159222,0.464259902,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,160011,DB00285,10016825,59,10892,7,3711,0.004232061,2.871679116,1.308375742,7.459018952,0.017881324,DB0028510016825_,4.023998489,1.054896917,female,10016825,Flushing,10047065,Vascular disorders,Vasc,venlafaxine,DB00285
,160013,DB00656,10016825,62,11951,20,6599,0.037117145,1.711685361,1.018758948,2.994957168,0.099828523,DB0065610016825_,2.304301337,0.537478477,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,trazodone,DB00656
,160016,DB00341,10021015,42,11363,21,5047,0.682120738,0.888334861,0.513733535,1.58070886,0.807782646,DB0034110021015_,0.21346226,-0.118406512,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,cetirizine,DB00341
,160024,DB00331,10037596,38,24908,18,20734,0.059161749,1.757312761,0.978275012,3.272185418,0.141924484,DB0033110037596_,1.952460163,0.563785802,NA,10037596,Pyelonephritis,10021881,Infections and infestations,Infec,metformin,DB00331
,160045,DB00169,10014551,44,38647,12,18163,0.113826867,1.723214897,0.894382377,3.584815165,0.231888332,DB0016910014551_,1.46149935,0.544191672,NA,10014551,Emotional disorder,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,160052,DB01006,10016256,1171,4776,20,157,0.004954915,1.924482432,1.198249212,3.251454492,0.020326021,DB0100610016256_,3.895853409,0.654657065,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,letrozole,DB01006
,160089,DB01307,10008190,42,2482,35,2034,1,0.983400702,0.610391139,1.593093306,1,DB0130710008190_,0,-0.01673861,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,insulin detemir,DB01307
,160090,DB01098,10069327,44,8105,25,7184,0.089965583,1.559955786,0.932903592,2.662803682,0.195135154,DB0109810069327_,1.634062864,0.444657479,NA,10069327,Product quality issue,10077536,Product issues,Prod,rosuvastatin,DB01098
,160103,DB00374,10017944,162,17554,57,5667,0.580384278,0.917517712,0.673421049,1.265665734,0.728953804,DB0037410017944_,0.316144919,-0.086083395,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,160120,DB00186,10051118,46,16855,33,9975,0.415553163,0.824965578,0.515818243,1.332691668,0.584748782,DB0018610051118_,0.536572956,-0.192413617,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,160124,DB00331,10057362,83,24863,93,20659,0.048801617,0.741578412,0.544542786,1.008492432,0.122792372,DB0033110057362_,2.097260385,-0.298974375,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,160126,DB01592,10044565,53,6223,24,3043,0.808401445,1.079847855,0.653593157,1.832714251,0.896602219,DB0159210044565_,0.109142972,0.076820156,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,iron,DB01592
,160156,DB00316,10061577,38,65436,16,36937,0.395379512,1.340624859,0.729779518,2.575704638,0.565042842,DB0031610061577_,0.570853723,0.293135818,NA,10061577,Ulcer haemorrhage,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,160188,DB00374,10048669,34,17682,26,5698,0.001335754,0.421418307,0.245263549,0.731976992,0.006987817,DB0037410048669_,4.963587066,-0.864129335,NA,10048669,Terminal state,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,160203,DB00588,10013774,46,16478,14,8454,0.10064589,1.685695774,0.909924645,3.321906062,0.211841545,DB0058810013774_,1.551916713,0.522178401,NA,10013774,Dry eye,10015919,Eye disorders,Eye,fluticasone propionate,DB00588
,160205,DB00575,10013781,43,5201,20,3809,0.097223227,1.574495049,0.904682019,2.830132008,0.206673071,DB0057510013781_,1.5766171,0.453934617,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,clonidine,DB00575
,160211,DB00829,10016825,63,7989,11,4443,0.000123234,3.1849228,1.662345868,6.710112074,0.000953412,DB0082910016825_,6.955463197,1.15842805,female,10016825,Flushing,10047065,Vascular disorders,Vasc,diazepam,DB00829
,160235,DB00951,10013710,35,617,64,501,0.000204262,0.444350461,0.280621614,0.693885572,0.001466546,DB0095110013710_,6.52484511,-0.811141701,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,isoniazid,DB00951
,160257,DB00668,10007882,59,10032,18,4285,0.260888597,1.400071366,0.813152809,2.525620332,0.42238385,DB0066810007882_,0.861840782,0.336523211,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,epinephrine,DB00668
,160266,DB00668,10030124,43,10048,24,4279,0.286831424,0.762987764,0.452099077,1.316306623,0.451607049,DB0066810030124_,0.794942839,-0.270513284,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,160268,DB14512,10030124,33,4811,17,2395,0.881470834,0.966382358,0.521795582,1.853768055,0.95045981,DB1451210030124_,0.050809401,-0.034195707,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,mometasone furoate,DB14512
,160288,DB00030,10019211,72,2134,37,1784,0.01888684,1.62659463,1.073678533,2.500936974,0.059071941,DB0003010019211_,2.828999243,0.486488645,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,insulin human,DB00030
,160321,DB00398,10005750,34,693,73,1465,1,0.984607866,0.628796138,1.515313194,1,DB0039810005750_,0,-0.015511822,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,sorafenib,DB00398
,160327,DB08895,10029410,84,28030,20,6626,1,0.992836279,0.603530196,1.708747713,1,DB0889510029410_,0,-0.007189504,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,160330,DB00734,10012575,41,4009,64,4838,0.236504519,0.773119298,0.508021105,1.164932981,0.393762234,DB0073410012575_,0.932008018,-0.257321912,NA,10012575,Device breakage,10077536,Product issues,Prod,risperidone,DB00734
,160338,DB01156,10039203,41,13581,19,6309,1,1.002441561,0.568224145,1.830235946,1,DB0115610039203_,0,0.002438585,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,160347,DB00186,10011781,55,16846,9,9999,7.32669922997212e-05,3.627126221,1.777330653,8.35378307,0.000610017,DB0018610011781_,7.402024135,1.28844066,female,10011781,Cystitis,10021881,Infections and infestations,Infec,lorazepam,DB00186
,160349,DB00455,10011781,44,9357,6,5112,0.000294728,4.006085368,1.699310786,11.51156736,0.00198894,DB0045510011781_,6.220153487,1.387814547,female,10011781,Cystitis,10021881,Infections and infestations,Infec,loratadine,DB00455
,160370,DB00722,10021137,22,25381,31,26001,0.273335529,0.727020243,0.400977429,1.297123261,0.436291142,DB0072210021137_,0.829445501,-0.318800957,NA,10021137,Hypovolaemia,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,160374,DB00451,10021639,54,47217,7,15412,0.016515761,2.518092181,1.141896552,6.561587784,0.053133748,DB0045110021639_,2.934943002,0.923501544,NA,10021639,Incontinence,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,160391,DB06228,10040047,114,15798,102,15974,0.375699622,1.130093407,0.856731681,1.49236578,0.545504313,DB0622810040047_,0.606044567,0.122300291,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,160393,DB01118,10048294,32,3031,40,4669,0.397670924,1.232287184,0.747479974,2.016765875,0.567392061,DB0111810048294_,0.566704748,0.208871942,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,amiodarone,DB01118
,160415,DB00598,10005750,33,1555,18,1010,0.664430067,1.190673944,0.647208993,2.258889017,0.795759981,DB0059810005750_,0.22845767,0.174519486,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,labetalol,DB00598
,160416,DB00598,10007515,30,1558,23,1005,0.570998263,0.841441465,0.469533557,1.526245075,0.72139819,DB0059810007515_,0.326564019,-0.172638829,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,labetalol,DB00598
,160417,DB01275,10007515,48,3931,44,3305,0.752248627,0.917196343,0.594776188,1.417447926,0.860362682,DB0127510007515_,0.150401255,-0.086433716,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,hydralazine,DB01275
,160434,DB01115,10033318,44,3556,10,2258,0.001834533,2.793491501,1.381631262,6.238298655,0.009063191,DB0111510033318_,4.703534059,1.027292248,female,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,nifedipine,DB01115
,160435,DB00575,10037423,39,5205,27,3802,0.90073174,1.055099359,0.628380366,1.795741563,0.956763316,DB0057510037423_,0.044199237,0.053634942,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonidine,DB00575
,160467,DB08910,10035528,231,16513,275,17213,0.151633294,0.875612208,0.730876857,1.048231824,0.28622127,DB0891010035528_,1.250990095,-0.132831971,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,pomalidomide,DB08910
,160502,DB00722,10069868,48,25355,17,26015,8.86129357896282e-05,2.897072505,1.635676284,5.375271433,0.000719664,DB0072210069868_,7.236726774,1.063700746,female,10069868,Device issue,10077536,Product issues,Prod,lisinopril,DB00722
,160509,DB00193,10016825,114,19206,23,8679,0.000189841,2.239748482,1.420521611,3.677522589,0.001379107,DB0019310016825_,6.586318994,0.806363575,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,tramadol,DB00193
,160514,DB00335,10033775,107,8359,36,5429,0.000528247,1.930309012,1.30973816,2.904669088,0.003229061,DB0033510033775_,5.735563794,0.6576801,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,160563,DB00868,10016173,98,2886,31,1615,0.005059639,1.768852233,1.164377265,2.754810936,0.020654234,DB0086810016173_,3.879834921,0.57033088,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,benzonatate,DB00868
,160564,DB11074,10016173,34,1226,26,842,0.691223341,0.898152362,0.518908049,1.571127829,0.813814047,DB1107410016173_,0.206023382,-0.107415557,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,dimethicone,DB11074
,160568,DB11074,10035664,53,1207,58,810,0.013047199,0.613396483,0.409896522,0.916252784,0.044012531,DB1107410035664_,3.123280898,-0.48874376,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,dimethicone,DB11074
,160577,DB00868,10047942,60,2924,20,1626,0.058634294,1.668092648,0.987041919,2.932836274,0.140942152,DB0086810047942_,1.959405745,0.511680847,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,benzonatate,DB00868
,160591,DB00043,10035664,92,6321,43,2257,0.167762576,0.76397546,0.524549274,1.128109369,0.307871209,DB0004310035664_,1.178073738,-0.269219611,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,omalizumab,DB00043
,160602,DB08868,10013887,57,9145,19,2492,0.482587319,0.817510856,0.478056092,1.45812881,0.646936513,DB0886810013887_,0.435507114,-0.201491096,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,160603,DB08868,10013950,60,9142,22,2489,0.226149259,0.742547764,0.44780845,1.273957991,0.381035623,DB0886810013950_,0.96486241,-0.297668082,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,fingolimod,DB08868
,160607,DB01069,10035226,32,6668,30,2365,0.000217985,0.378371736,0.222129344,0.646141556,0.001549207,DB0106910035226_,6.470011777,-0.971878139,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,promethazine,DB01069
,160608,DB00433,10048294,48,7608,59,5961,0.024145298,0.637469157,0.425532868,0.950723742,0.071571374,DB0043310048294_,2.637060084,-0.450249384,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,prochlorperazine,DB00433
,160614,DB00635,10053555,31,33022,26,23768,0.592496628,0.858183594,0.492950928,1.505216772,0.738653664,DB0063510053555_,0.302926122,-0.152937224,NA,10053555,Arthritis bacterial,10021881,Infections and infestations,Infec,prednisone,DB00635
,160636,DB01075,10027091,48,19900,19,11078,0.250650674,1.406343316,0.810910687,2.534933216,0.410463708,DB0107510027091_,0.890467763,0.340992943,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,160639,DB00003,10000087,45,2953,37,2556,0.91127147,1.052712486,0.663904928,1.678470596,0.960127091,DB0000310000087_,0.040689617,0.051370153,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,dornase alfa,DB00003
,160642,DB00341,10000087,167,11238,40,5028,0.000254617,1.86787698,1.313706771,2.712489436,0.001763301,DB0034110000087_,6.340567399,0.624802481,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,160648,DB00472,10003553,57,10702,12,4300,0.044324975,1.908451684,1.011229563,3.912178023,0.114257327,DB0047210003553_,2.16930212,0.646292277,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,160650,DB00043,10003988,57,6356,14,2286,0.225179193,1.464224828,0.803685359,2.851249531,0.380045916,DB0004310003988_,0.967463202,0.381325975,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,omalizumab,DB00043
,160652,DB00668,10003988,112,9979,36,4267,0.14896251,1.330235448,0.904762413,1.997873037,0.282542905,DB0066810003988_,1.263924863,0.285355955,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,epinephrine,DB00668
,160653,DB14512,10003988,66,4778,33,2379,1,0.995814152,0.644170427,1.566418817,1,DB1451210003988_,0,-0.004194633,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,mometasone furoate,DB14512
,160659,DB00588,10011762,50,16474,44,8424,0.011571191,0.581074109,0.379375852,0.892855638,0.040027472,DB0058810011762_,3.218189272,-0.542876976,NA,10011762,Cystic fibrosis,10010331,"Congenital, familial and genetic disorders",Cong,fluticasone propionate,DB00588
,160667,DB00471,10013946,80,14109,40,5425,0.184128612,0.769013877,0.519101057,1.155493249,0.329073482,DB0047110013946_,1.111474203,-0.262646264,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,160673,DB00003,10028810,54,2944,56,2537,0.336476862,0.831005713,0.558811575,1.234810673,0.505525715,DB0000310028810_,0.682156371,-0.18511861,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,dornase alfa,DB00003
,160676,DB00537,10028810,64,7493,26,4272,0.153683027,1.403363898,0.875387069,2.310594708,0.289063831,DB0053710028810_,1.241107746,0.338872138,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,160677,DB00668,10028810,232,9859,108,4195,0.43655358,0.914045401,0.722183284,1.162856184,0.605131753,DB0066810028810_,0.502309072,-0.089875036,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,epinephrine,DB00668
,160683,DB00472,10039101,35,10724,18,4294,0.446181262,0.778571234,0.428627047,1.461956332,0.614024842,DB0047210039101_,0.487719893,-0.25029479,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,160684,DB00668,10039101,39,10052,14,4289,0.653801402,1.188587758,0.630580201,2.372519794,0.787786558,DB0066810039101_,0.238528092,0.172765844,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,160685,DB00003,10040753,48,2950,42,2551,1,0.988281451,0.637137159,1.538101916,1,DB0000310040753_,0,-0.011787753,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,dornase alfa,DB00003
,160688,DB00472,10040753,153,10606,29,4283,9.27241758977419e-05,2.130451721,1.422806223,3.293457745,0.000747739,DB0047210040753_,7.198456697,0.756334033,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,fluoxetine,DB00472
,160691,DB00169,10052140,60,38631,12,18163,0.00502152,2.350802046,1.251400975,4.801748388,0.020535302,DB0016910052140_,3.885609835,0.854756566,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,160699,DB06228,10020642,55,15857,47,16029,0.428198711,1.182898372,0.786278388,1.785908623,0.596713133,DB0622810020642_,0.516318796,0.167967674,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,rivaroxaban,DB06228
,160716,DB00563,10031009,92,46554,35,15313,0.471544261,0.864639518,0.579696481,1.315848972,0.637743293,DB0056310031009_,0.449819439,-0.145442601,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,160717,DB00537,10037153,31,7526,22,4276,0.474330313,0.800622926,0.44823353,1.453231018,0.639996524,DB0053710037153_,0.446292534,-0.222365196,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,ciprofloxacin,DB00537
,160720,DB00999,10020028,44,21386,14,12225,0.05606704,1.796539331,0.965805121,3.551048049,0.136201737,DB0099910020028_,1.993618128,0.585862221,NA,10020028,Hiatus hernia,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,160730,DB00656,10055798,35,11978,26,6593,0.283515522,0.740993873,0.433030957,1.282976948,0.447889263,DB0065610055798_,0.803209259,-0.299762923,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,trazodone,DB00656
,160768,DB01281,10013700,287,8645,48,1750,0.264549089,1.210336152,0.88483175,1.686668846,0.426508868,DB0128110013700_,0.85212212,0.190898132,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,abatacept,DB01281
,160776,DB08895,10018836,61,28053,30,6616,0.001847021,0.479540716,0.304639059,0.769849846,0.00911375,DB0889510018836_,4.697970983,-0.734926475,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,160779,DB01273,10016256,79,1961,37,1238,0.146034232,1.34781569,0.894724384,2.063036532,0.278495959,DB0127310016256_,1.27835173,0.298485274,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,varenicline,DB01273
,160791,DB00316,10010254,61,65413,22,36931,0.085606144,1.565424871,0.947387915,2.677904939,0.187732145,DB0031610010254_,1.672739091,0.44815727,NA,10010254,Concussion,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,160794,DB00996,10010254,55,38898,11,22414,0.000497535,2.881073093,1.491170939,6.10664135,0.00307892,DB0099610010254_,5.783176342,1.058162827,female,10010254,Concussion,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,160803,DB00814,10021097,72,8215,40,3375,0.143214962,0.739513716,0.494574591,1.119801542,0.274335812,DB0081410021097_,1.293402333,-0.30176245,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,meloxicam,DB00814
,160805,DB01142,10021097,45,1695,9,775,0.024674364,2.285511174,1.096200501,5.344579788,0.072790758,DB0114210021097_,2.620166278,0.826589708,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,doxepin,DB01142
,160807,DB00814,10024855,46,8241,11,3404,0.109140376,1.727256781,0.87998483,3.702481055,0.224735979,DB0081410024855_,1.492828992,0.546534474,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,160824,DB00051,10048706,90,25641,27,11393,0.087394563,1.481100158,0.953545878,2.370641192,0.190770759,DB0005110048706_,1.656682788,0.392785162,NA,10048706,Joint range of motion decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,160836,DB00480,10018836,121,67307,120,67542,0.948646959,1.011854883,0.779319407,1.313848896,0.987043456,DB0048010018836_,0.013041212,0.011785165,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,160869,DB00904,10022086,97,22972,23,14433,7.54783141720087e-06,2.649649804,1.667278704,4.378242866,8.48022008126201e-05,DB0090410022086_,9.375189063,0.974427482,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,160887,DB00343,10033557,135,8601,29,5066,8.41783268899988e-08,2.741720234,1.821777848,4.255381799,1.54729183377875e-06,DB0034310033557_,13.37900436,1.008585546,female,10033557,Palpitations,10007541,Cardiac disorders,Card,diltiazem,DB00343
,160893,DB00959,10033557,69,8009,17,4985,0.000315327,2.526149617,1.467394084,4.587745742,0.002102046,DB0095910033557_,6.164843953,0.926696253,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,methylprednisolone,DB00959
,160921,DB01076,10033664,34,25713,23,25560,0.184734304,1.469446754,0.840418698,2.613450809,0.329840109,DB0107610033664_,1.109147259,0.384885972,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,160931,DB00281,10001053,39,11419,38,5633,0.003362789,0.50628733,0.315094445,0.814228291,0.014825716,DB0028110001053_,4.211392064,-0.680650924,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,160943,DB00437,10044565,60,6861,88,11458,0.443870458,1.138636576,0.804963531,1.601275916,0.611877887,DB0043710044565_,0.491222548,0.129831561,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,160949,DB00404,10014011,48,19844,6,9856,0.000251106,3.972903307,1.697111019,11.36524261,0.001742427,DB0040410014011_,6.352476218,1.379497139,female,10014011,Ear infection,10021881,Infections and infestations,Infec,alprazolam,DB00404
,160950,DB00455,10014011,38,9363,14,5104,0.245434319,1.479585834,0.78276042,2.959245259,0.404251093,DB0045510014011_,0.905719076,0.391762207,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,loratadine,DB00455
,160954,DB00956,10040753,63,5751,17,3450,0.002402355,2.222970354,1.282226733,4.059671343,0.011300267,DB0095610040753_,4.482928957,0.798844299,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,hydrocodone,DB00956
,160955,DB01069,10040753,120,6580,16,2379,4.69774234212385e-05,2.711618244,1.598959649,4.906439892,0.000418932,DB0106910040753_,7.777802344,0.997545595,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,promethazine,DB01069
,160963,DB00455,10047899,150,9251,48,5070,0.000945282,1.712593894,1.227373651,2.427174531,0.005257457,DB0045510047899_,5.248107844,0.538009119,NA,10047899,Weight increased,10022891,Investigations,Inv,loratadine,DB00455
,160965,DB01069,10051398,45,6655,25,2370,0.077405113,0.641056385,0.383804466,1.093456944,0.173941472,DB0106910051398_,1.749036402,-0.444637862,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,promethazine,DB01069
,160974,DB00091,10021789,85,5425,41,2629,1,1.004675183,0.682122155,1.500781732,1,DB0009110021789_,0,0.004664288,NA,10021789,Infection,10021881,Infections and infestations,Infec,cyclosporine,DB00091
,160987,DB00635,10027940,43,33010,14,23780,0.010050452,2.212572802,1.187035418,4.379996235,0.035711542,DB0063510027940_,3.332281342,0.794156002,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,160989,DB00814,10001760,107,8180,7,3408,1.15728275427371e-09,6.367994514,2.981813508,16.23368276,3.17362307731711e-08,DB0081410001760_,17.26580688,1.851284587,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,meloxicam,DB00814
,160997,DB01017,10013700,111,1358,16,885,1.05976038544114e-10,4.518885388,2.641093338,8.238202183,3.43686634562868e-09,DB0101710013700_,19.48870573,1.508265368,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,minocycline,DB01017
,161045,DB00399,10017413,88,6904,60,4938,0.801815447,1.049017804,0.74542466,1.484903808,0.892794236,DB0039910017413_,0.113399143,0.047854302,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,zoledronic acid,DB00399
,161047,DB01076,10017413,123,25624,135,25448,0.453962259,0.90485982,0.702450086,1.164726851,0.62149483,DB0107610017413_,0.475627686,-0.099975243,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,161048,DB01373,10017413,184,22536,85,7296,0.008322553,0.700829893,0.538296742,0.918577976,0.030724483,DB0137310017413_,3.482695453,-0.355490085,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,calcium,DB01373
,161049,DB13961,10017413,67,9390,50,6364,0.636782555,0.908181352,0.619373168,1.339277839,0.774232199,DB1396110017413_,0.255883452,-0.096311193,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,fish oil,DB13961
,161051,DB08910,10044565,218,16526,126,17362,6.72381454058604e-08,1.817636722,1.451495266,2.284155579,1.26420218311376e-06,DB0891010044565_,13.58106932,0.597537153,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,161066,DB01136,10028391,54,9830,51,11064,0.379307897,1.191729528,0.796748793,1.784742017,0.54931725,DB0113610028391_,0.599079136,0.175405637,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,carvedilol,DB01136
,161071,DB08895,10054107,106,28008,21,6625,0.499583237,1.193954688,0.741901308,2.009977105,0.661372159,DB0889510054107_,0.413438574,0.177271064,NA,10054107,Nodule,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,161073,DB01611,10037153,76,11837,16,2345,0.779188712,0.941004344,0.542685616,1.732283919,0.879672513,DB0161110037153_,0.128205585,-0.060807523,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxychloroquine,DB01611
,161113,DB00264,10064911,112,29495,37,24855,2.2035186359969e-07,2.550707215,1.744080279,3.808092011,3.70092570908488e-06,DB0026410064911_,12.50692758,0.93637066,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,161141,DB00335,10006002,37,8429,15,5450,0.154283551,1.594838899,0.853445337,3.131119197,0.289884781,DB0033510006002_,1.23827174,0.466772727,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,161153,DB01069,10030124,74,6626,28,2367,0.821192144,0.944107327,0.601933965,1.519160662,0.904725148,DB0106910030124_,0.100124085,-0.057515425,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,161176,DB00126,10006784,63,10108,23,5922,0.056459608,1.60473681,0.980236683,2.71414065,0.136892123,DB0012610006784_,1.988562088,0.472959762,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,161177,DB00482,10006784,47,8212,9,3062,0.070087908,1.947152207,0.94186703,4.524641584,0.161396528,DB0048210006784_,1.823891036,0.666367898,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,161191,DB00559,10047513,45,9614,10,3296,0.277041252,1.542652737,0.765344057,3.437278,0.440553812,DB0055910047513_,0.819722679,0.433503491,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,bosentan,DB00559
,161209,DB00575,10013950,32,5212,24,3805,1,0.973386864,0.554616544,1.73001606,1,DB0057510013950_,0,-0.026973676,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,clonidine,DB00575
,161225,DB00213,10031282,49,18846,6,13415,1.34498273766303e-06,5.812973349,2.486712824,16.60948557,1.86805132150451e-05,DB0021310031282_,10.88802965,1.760092204,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,161243,DB00153,10038695,50,7373,27,3412,0.539353502,0.857004247,0.525354177,1.426323215,0.695210901,DB0015310038695_,0.363540025,-0.154312405,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,161263,DB00343,10008469,108,8628,33,5062,0.00079659,1.920006989,1.287262743,2.93282117,0.004558261,DB0034310008469_,5.390814044,0.652328826,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,161270,DB01377,10047895,91,3705,66,2604,0.869815979,0.969048027,0.69518785,1.356921414,0.942090076,DB0137710047895_,0.059654387,-0.031441105,NA,10047895,Weight decreased,10022891,Investigations,Inv,magnesium oxide,DB01377
,161300,DB00497,10051118,28,19239,30,16345,0.429345536,0.792946632,0.456275698,1.374041036,0.597851689,DB0049710051118_,0.514412567,-0.231999359,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,161305,DB00563,10072268,35,46611,22,15326,0.020557119,0.523135127,0.298293582,0.936365908,0.063159682,DB0056310072268_,2.762089128,-0.647915479,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,methotrexate,DB00563
,161314,DB00982,10053762,134,3230,97,2004,0.269081651,0.8571229,0.651011822,1.131773041,0.431597938,DB0098210053762_,0.840260824,-0.154173964,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,isotretinoin,DB00982
,161318,DB01432,10047895,40,1251,18,652,0.674782465,1.158084056,0.64282115,2.164213327,0.802790166,DB0143210047895_,0.219661912,0.146766963,NA,10047895,Weight decreased,10022891,Investigations,Inv,cholestyramine,DB01432
,161354,DB00682,10007632,46,19413,11,16353,4.53212836674744e-05,3.522437621,1.796596104,7.542993839,0.000406369,DB0068210007632_,7.808249601,1.259153256,female,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,warfarin,DB00682
,161358,DB01362,10002198,32,834,26,564,0.49815006,0.832430433,0.474850264,1.471540026,0.66013987,DB0136210002198_,0.415303542,-0.183405625,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,iohexol,DB01362
,161363,DB00734,10010774,39,4011,34,4868,0.19371018,1.392077469,0.85445355,2.277990562,0.341336167,DB0073410010774_,1.074887459,0.330797213,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,risperidone,DB00734
,161385,DB00734,10043414,31,4019,29,4873,0.362658347,1.296064911,0.75421878,2.23313147,0.532228283,DB0073410043414_,0.630682778,0.259332682,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,161387,DB00502,10047700,36,1358,27,1845,0.020719067,1.811113196,1.063548663,3.11846087,0.063545962,DB0050210047700_,2.755991817,0.593941681,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,haloperidol,DB00502
,161424,DB00158,10003553,75,16740,23,8081,0.065605479,1.574112619,0.974558614,2.634519194,0.153494218,DB0015810003553_,1.87409238,0.453691697,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,161428,DB01098,10003553,56,8093,8,7201,7.56875702081394e-09,6.227848151,2.950647249,15.1372198,1.74742888267101e-07,DB0109810003553_,15.55995015,1.829030872,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,161446,DB00654,10061818,32,3784,21,2577,1,1.037750579,0.578770127,1.898129302,1,DB0065410061818_,0,0.037055466,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,161448,DB00051,10024690,69,25662,39,11381,0.250356806,0.784622914,0.522064982,1.194458999,0.410097444,DB0005110024690_,0.89136048,-0.242552041,NA,10024690,Liver function test abnormal,10022891,Investigations,Inv,adalimumab,DB00051
,161456,DB00921,10013700,117,5728,32,4871,1.15380367008328e-09,3.108772844,2.082995209,4.761404944,3.16573376494145e-08,DB0092110013700_,17.26829588,1.134228064,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,buprenorphine,DB00921
,161458,DB00722,10015967,65,25338,49,25983,0.111091384,1.360284832,0.924048961,2.01384375,0.227718712,DB0072210015967_,1.479644132,0.307694113,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,lisinopril,DB00722
,161477,DB01285,10011906,59,1217,42,567,0.048538943,0.654623468,0.427442401,1.009983716,0.122314314,DB0128510011906_,2.101161205,-0.423695067,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,corticotropin,DB01285
,161483,DB01296,10011906,29,1420,43,940,0.000907699,0.446593996,0.266815667,0.737813097,0.005088262,DB0129610011906_,5.280819037,-0.806105382,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,glucosamine,DB01296
,161489,DB00787,10003553,61,16939,12,17236,2.2511281658157e-09,5.172050088,2.756134084,10.55822522,5.80961255164119e-08,DB0078710003553_,16.66116686,1.643269145,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,161491,DB06228,10006451,116,15796,39,16037,2.38193053746365e-10,3.019773392,2.082895797,4.46247679,7.3355646370512e-09,DB0622810006451_,18.73053145,1.105181793,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,161492,DB00421,10020751,82,8821,23,5229,0.00108137,2.113322346,1.315397121,3.522134593,0.005875673,DB0042110020751_,5.136934693,0.748261281,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,spironolactone,DB00421
,161508,DB00455,10054112,88,9313,60,5058,0.194404858,0.796592541,0.566163563,1.127262667,0.342247861,DB0045510054112_,1.072220065,-0.227411972,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,loratadine,DB00455
,161511,DB08895,10047895,231,27883,62,6584,0.370836207,0.879751274,0.661148817,1.18570148,0.540525795,DB0889510047895_,0.615212918,-0.128116054,NA,10047895,Weight decreased,10022891,Investigations,Inv,tofacitinib,DB08895
,161512,DB08895,10064355,39,28075,17,6629,0.04031419,0.54169948,0.299130133,1.021865594,0.10626553,DB0889510064355_,2.241814316,-0.613043895,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,161543,DB01234,10000846,18,31607,40,32848,0.008031006,0.467675794,0.252285888,0.834986282,0.029875361,DB0123410000846_,3.51072119,-0.759979972,NA,10000846,Acute lymphocytic leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,161553,DB00433,10007882,54,7602,48,5972,0.549237265,0.88378988,0.586984064,1.334155886,0.703578901,DB0043310007882_,0.351575254,-0.123535937,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,161555,DB00727,10007882,33,3810,32,4141,0.708930849,1.120824839,0.666595035,1.886610646,0.826298175,DB0072710007882_,0.190799584,0.114064878,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,nitroglycerin,DB00727
,161559,DB00646,10008531,43,3410,21,1979,0.602257803,1.188340316,0.687570584,2.114501645,0.746309613,DB0064610008531_,0.292614734,0.172557641,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,161561,DB00196,10010305,42,5041,52,3233,0.001911397,0.518036878,0.3357154,0.795270452,0.009376832,DB0019610010305_,4.669513338,-0.657708846,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,fluconazole,DB00196
,161566,DB00264,10012218,43,29564,66,24826,0.001989119,0.547114739,0.363534955,0.81581056,0.009682222,DB0026410012218_,4.637463832,-0.603096738,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,161570,DB00722,10012218,41,25362,38,25994,0.735748214,1.105829047,0.693463102,1.767384067,0.847316062,DB0072210012218_,0.165681499,0.100595323,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,161572,DB00904,10012218,45,23024,31,14425,0.723796878,0.909468474,0.562684511,1.487393922,0.837662951,DB0090410012218_,0.177139465,-0.094894944,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,161578,DB00152,10013968,46,785,38,826,0.314096781,1.273565197,0.801049291,2.035132849,0.481654156,DB0015210013968_,0.730528942,0.24182021,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,thiamine,DB00152
,161580,DB00537,10015090,38,7519,15,4283,0.254064523,1.443004124,0.774400971,2.827260043,0.414661855,DB0053710015090_,0.880291898,0.366727137,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ciprofloxacin,DB00537
,161584,DB00433,10015150,79,7577,24,5996,1.44325031300024e-05,2.604612789,1.629319459,4.307912152,0.000150003,DB0043310015150_,8.804853267,0.957284023,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,prochlorperazine,DB00433
,161586,DB00787,10015150,86,16914,67,17181,0.105713361,1.303830236,0.9356457,1.823492953,0.219692891,DB0078710015150_,1.515524659,0.265306268,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,161587,DB00836,10015150,60,5475,16,4059,0.000102725,2.779814383,1.577895784,5.179371247,0.000816734,DB0083610015150_,7.110196722,1.022384157,female,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,loperamide,DB00836
,161596,DB00860,10019211,72,1811,26,1470,0.000278729,2.247250306,1.408841987,3.687377939,0.001901233,DB0086010019211_,6.265252465,0.809707383,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,prednisolone,DB00860
,161597,DB01413,10019211,35,1185,23,1636,0.006813983,2.100374258,1.199338919,3.743911835,0.026231041,DB0141310019211_,3.640811799,0.742115547,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cefepime,DB01413
,161600,DB00715,10020772,56,4787,31,2256,0.488848057,0.851369227,0.537822462,1.370243611,0.652368247,DB0071510020772_,0.42714608,-0.16090937,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,paroxetine,DB00715
,161601,DB00787,10020772,155,16845,130,17118,0.108642627,1.211622117,0.952513326,1.543306708,0.224000585,DB0078710020772_,1.496106617,0.191960054,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,acyclovir,DB00787
,161605,DB00437,10020937,53,6868,78,11468,0.470553721,1.134577127,0.783882343,1.63120986,0.636813209,DB0043710020937_,0.451278902,0.126260006,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,161611,DB00433,10024264,32,7624,21,5999,0.580356976,1.199004362,0.669611209,2.19029212,0.728950619,DB0043310024264_,0.316149287,0.181491514,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,161613,DB00836,10024264,98,5437,64,4011,0.47144152,1.129589779,0.813745736,1.577398775,0.637669961,DB0083610024264_,0.449934433,0.121854539,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,161620,DB00646,10028411,46,3407,18,1982,0.191535831,1.486575634,0.842664516,2.732047067,0.3385575,DB0064610028411_,1.083061333,0.396475243,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,nystatin,DB00646
,161621,DB00727,10028411,54,3789,48,4125,0.320034591,1.224728366,0.812550283,1.850879742,0.488210397,DB0072710028411_,0.717008826,0.202719078,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,nitroglycerin,DB00727
,161622,DB00836,10028411,59,5476,21,4054,0.003039445,2.07978659,1.242768188,3.610016697,0.013663142,DB0083610028411_,4.293053439,0.732265288,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,loperamide,DB00836
,161626,DB00860,10033371,50,1833,21,1475,0.015158012,1.915561899,1.123793818,3.373773644,0.04972895,DB0086010033371_,3.001168025,0.650011,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,prednisolone,DB00860
,161628,DB00512,10033425,34,4703,18,5080,0.017178149,2.040145485,1.118583416,3.842724302,0.054833645,DB0051210033425_,2.903451309,0.713021121,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,vancomycin,DB00512
,161630,DB00186,10038063,48,16853,29,9979,1,0.980052283,0.605115395,1.6129342,1,DB0018610038063_,0,-0.020149359,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,161640,DB00196,10041349,53,5030,26,3259,0.29743122,1.320701778,0.809418238,2.204999704,0.463342595,DB0019610041349_,0.769288552,0.278163246,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,fluconazole,DB00196
,161642,DB00433,10041349,63,7593,33,5987,0.063050917,1.505251759,0.971369127,2.371594499,0.149049539,DB0043310041349_,1.90347655,0.408960166,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,161643,DB00727,10041349,50,3793,40,4133,0.167658547,1.361988551,0.878497714,2.12374345,0.307755501,DB0072710041349_,1.178449639,0.308945802,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,161644,DB00787,10041349,111,16889,100,17148,0.407580002,1.127017768,0.851598934,1.493108037,0.577004341,DB0078710041349_,0.549905489,0.119575001,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,161645,DB00836,10041349,105,5430,70,4005,0.537626477,1.106373235,0.807491865,1.523654021,0.693745088,DB0083610041349_,0.365650695,0.10108731,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,161647,DB01015,10041349,57,9830,60,9321,0.579328341,0.900814046,0.6150077,1.318140175,0.728070407,DB0101510041349_,0.317357522,-0.104456429,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,161649,DB00646,10042674,38,3415,12,1988,0.075967636,1.843247176,0.940254607,3.884045543,0.171426953,DB0064610042674_,1.763598032,0.611528786,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,161653,DB11089,10042674,60,10115,38,8369,0.222239232,1.30637734,0.854967647,2.018293976,0.376344969,DB1108910042674_,0.977249086,0.267257917,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,161654,DB00196,10048294,22,5061,36,3249,0.000606475,0.392357113,0.219467648,0.686690743,0.003631663,DB0019610048294_,5.618064717,-0.935582852,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,fluconazole,DB00196
,161655,DB00715,10048294,31,4812,42,2245,6.98403048795979e-06,0.344409381,0.208712526,0.562728728,7.92639211468148e-05,DB0071510048294_,9.442727499,-1.065924268,male,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,paroxetine,DB00715
,161656,DB00836,10048294,30,5505,27,4048,0.502021825,0.817057076,0.468642073,1.430858286,0.663381026,DB0083610048294_,0.410405754,-0.202046326,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,loperamide,DB00836
,161658,DB01413,10048294,48,1172,57,1602,0.483133661,1.151009043,0.761359985,1.733814248,0.6473225,DB0141310048294_,0.434910655,0.140638986,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,cefepime,DB01413
,161662,DB00836,10050584,56,5479,17,4058,0.000784826,2.4395421,1.394433759,4.48549578,0.0045032,DB0083610050584_,5.40296707,0.891810358,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,loperamide,DB00836
,161668,DB00646,10061818,46,3407,22,1978,0.527252232,1.213831354,0.713070161,2.125657947,0.684879755,DB0064610061818_,0.378511996,0.193781765,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,161671,DB00341,10006784,43,11362,14,5054,0.388323483,1.366248762,0.732330799,2.706492894,0.558328515,DB0034110006784_,0.582807753,0.312068854,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,161673,DB00588,10006784,76,16448,24,8444,0.043647577,1.625659791,1.01483382,2.692889716,0.112893144,DB0058810006784_,2.181313539,0.485913759,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,161677,DB01156,10006784,57,13565,11,6317,0.005666924,2.413000274,1.251361127,5.107694875,0.022615364,DB0115610006784_,3.789125764,0.8808709,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,161679,DB11089,10006784,44,10131,25,8382,0.146457453,1.456124691,0.870966384,2.484900541,0.278999431,DB1108910006784_,1.276545536,0.375778586,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,docusate,DB11089
,161682,DB00341,10008469,124,11281,47,5021,0.404861263,1.174244268,0.831530608,1.682621459,0.574594547,DB0034110008469_,0.554090623,0.160624765,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,161688,DB00215,10020100,36,11067,15,5261,0.764827939,1.140889261,0.608611777,2.245030707,0.870206145,DB0021510020100_,0.139025147,0.131808012,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,161694,DB01156,10020100,30,13592,22,6306,0.10280857,0.632668449,0.35262091,1.152067247,0.215213097,DB0115610020100_,1.536126592,-0.457808772,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,161695,DB11089,10020100,55,10120,30,8377,0.079966388,1.517535959,0.954631831,2.455371876,0.178362809,DB1108910020100_,1.723935551,0.41708794,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,161705,DB01062,10027175,58,4428,18,1727,0.442636914,1.25666344,0.727413397,2.273288415,0.610681886,DB0106210027175_,0.4931791,0.228460145,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,161706,DB13867,10027175,59,4491,6,2548,1.4016042368687e-06,5.578956748,2.41102547,15.83728865,1.93951920853349e-05,DB1386710027175_,10.85048535,1.719001796,female,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,fluticasone,DB13867
,161712,DB13867,10033318,44,4506,18,2536,0.288824491,1.375687039,0.776862128,2.535359142,0.453902828,DB1386710033318_,0.789872139,0.318953271,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,fluticasone,DB13867
,161713,DB00215,10033664,38,11065,18,5258,1,1.003183357,0.558056355,1.869227875,1,DB0021510033664_,0,0.003178301,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,161717,DB00425,10033664,43,12652,18,7466,0.235016019,1.409670631,0.795406673,2.598779408,0.392041382,DB0042510033664_,0.93638788,0.343356082,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,161721,DB01156,10033664,67,13555,20,6308,0.083846118,1.558935365,0.933360758,2.715130609,0.184820765,DB0115610033664_,1.688368762,0.44400313,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,161727,DB13867,10035598,40,4510,18,2536,0.493411169,1.249567704,0.698306003,2.320713437,0.656109302,DB1386710035598_,0.421427884,0.222797655,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,161731,DB00404,10038683,39,19853,12,9850,0.179823456,1.612452831,0.826687546,3.384029967,0.323632971,DB0040410038683_,1.128145212,0.477756517,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,161777,DB00341,10061822,69,11336,25,5043,0.433269688,1.227795065,0.765911796,2.027992357,0.601769815,DB0034110061822_,0.507880275,0.205219931,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,161807,DB00230,10002198,57,19617,14,8637,0.052466245,1.792541588,0.985518653,3.485369912,0.129636704,DB0023010002198_,2.043019327,0.583634494,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,pregabalin,DB00230
,161808,DB00448,10046735,56,5089,22,3102,0.099757925,1.551503679,0.930106016,2.674376864,0.210427498,DB0044810046735_,1.558614114,0.439224576,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,lansoprazole,DB00448
,161827,DB00364,10020937,38,2712,12,1388,0.175418902,1.620525456,0.825754989,3.417660034,0.317942121,DB0036410020937_,1.145885921,0.482750452,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,sucralfate,DB00364
,161828,DB00704,10010774,36,4320,17,5177,0.001288229,2.537513187,1.386630418,4.824747792,0.006776966,DB0070410010774_,4.994225769,0.931184541,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,naltrexone,DB00704
,161843,DB00028,10022086,126,13332,33,5582,0.014455881,1.598619654,1.080722529,2.425290026,0.047828414,DB0002810022086_,3.040135385,0.46914054,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,161845,DB00028,10053425,103,13355,23,5592,0.005768551,1.87508196,1.182829195,3.092038474,0.022947615,DB0002810053425_,3.774541287,0.62865237,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,161870,DB09053,10028372,20,2265,43,4009,0.512220354,0.823297861,0.457588445,1.434217899,0.672462319,DB0905310028372_,0.3968092,-0.194437222,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,ibrutinib,DB09053
,161884,DB00564,10048294,37,2567,14,1449,0.240689525,1.491681328,0.784515275,2.997516735,0.398685753,DB0056410048294_,0.919581758,0.399903892,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,carbamazepine,DB00564
,161889,DB00186,10003246,79,16822,17,9991,4.59104578909049e-05,2.759901338,1.618382698,4.976398179,0.000410511,DB0018610003246_,7.798107971,1.015194932,female,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,161890,DB01136,10003246,46,9838,35,11080,0.093886293,1.480167789,0.932196507,2.369080619,0.201582509,DB0113610003246_,1.601556508,0.392155452,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,carvedilol,DB01136
,161904,DB00341,10000060,101,11304,22,5046,0.001588132,2.049262548,1.280737455,3.418427611,0.008047646,DB0034110000060_,4.82237562,0.717479996,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,161906,DB00584,10000081,38,2043,38,1836,0.645072648,0.898703287,0.555269493,1.454529875,0.780833021,DB0058410000081_,0.247393954,-0.106802347,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,enalapril,DB00584
,161918,DB00341,10060795,56,11349,21,5047,0.538868502,1.18586633,0.705894167,2.064308214,0.694766738,DB0034110060795_,0.364179119,0.170473587,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,cetirizine,DB00341
,161925,DB08893,10003549,63,2022,41,1017,0.206975399,0.772941983,0.509417854,1.183817332,0.357600064,DB0889310003549_,1.028340056,-0.257551288,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,mirabegron,DB08893
,161928,DB08893,10010305,46,2039,49,1009,0.000359978,0.464667988,0.301565601,0.71489355,0.002348187,DB0889310010305_,6.054111713,-0.766432132,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,mirabegron,DB08893
,161955,DB00706,10017885,9,1066,58,15867,0.037044042,2.309517992,1.003150288,4.710585817,0.09968801,DB0070610017885_,2.305709872,0.837038841,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,tamsulosin,DB00706
,161957,DB01137,10017885,44,7728,17,5576,0.027092609,1.867404471,1.044350633,3.489810873,0.078219915,DB0113710017885_,2.548230996,0.624549483,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,161964,DB00215,10021015,32,11071,33,5243,0.002022375,0.459244082,0.273087678,0.771464226,0.009813206,DB0021510021015_,4.624026226,-0.778173441,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,citalopram,DB00215
,161970,DB00761,10025082,62,15245,18,8607,0.010311244,1.944609297,1.134593178,3.495646626,0.036463211,DB0076110025082_,3.311451441,0.665061082,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,161981,DB00588,10038428,48,16476,24,8444,1,1.025005719,0.615127565,1.750935732,1,DB0058810038428_,0,0.024698193,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,fluticasone propionate,DB00588
,161984,DB00695,10041232,55,27994,10,20518,6.30432605455402e-06,4.031057719,2.034362038,8.873269997,7.25363144425268e-05,DB0069510041232_,9.531423233,1.394028803,female,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,162010,DB00695,10064780,33,28016,22,20506,0.78588702,1.097931211,0.620967828,1.977272897,0.883799408,DB0069510064780_,0.123525156,0.093427691,NA,10064780,Breath sounds abnormal,10022891,Investigations,Inv,furosemide,DB00695
,162036,DB00136,10000081,34,2058,25,1657,0.792494482,1.095011116,0.631481949,1.922757903,0.887531177,DB0013610000081_,0.119311629,0.090764515,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,calcitriol,DB00136
,162037,DB00863,10000081,219,10454,96,5744,0.074102165,1.253462836,0.979411644,1.613988294,0.168376159,DB0086310000081_,1.781554759,0.22590999,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,162047,DB00687,10019211,91,895,37,1048,4.18829067244856e-08,2.87849227,1.921840391,4.387096452,8.2125490731302e-07,DB0068710019211_,14.01243229,1.05726664,female,10019211,Headache,10029205,Nervous system disorders,Nerv,fludrocortisone,DB00687
,162049,DB00584,10030124,30,2051,30,1844,0.697867544,0.899098394,0.521445999,1.550227827,0.818262916,DB0058410030124_,0.200571581,-0.106362802,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,enalapril,DB00584
,162052,DB00175,10061822,52,8079,47,6059,0.360823301,0.829767711,0.547617033,1.260247973,0.530750188,DB0017510061822_,0.633463825,-0.186609484,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,162053,DB00722,10061822,138,25265,117,25915,0.132294064,1.209825658,0.938210722,1.562239105,0.259045694,DB0072210061822_,1.350750808,0.190476265,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,162058,DB00656,10012174,119,11894,63,6556,0.815959899,1.041159872,0.759630489,1.438646227,0.90134507,DB0065610012174_,0.103867109,0.040335354,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,trazodone,DB00656
,162061,DB00213,10060933,65,18830,29,13392,0.036208144,1.594056525,1.013601687,2.5633018,0.097953412,DB0021310060933_,2.323263298,0.466282041,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,162065,DB00186,10022061,70,16831,14,9994,5.84051728478946e-05,2.968814875,1.656028468,5.710787214,0.000504224,DB0018610022061_,7.592490216,1.088162841,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,162066,DB00316,10022061,331,65143,57,36896,5.77202166189647e-21,3.288966946,2.47620546,4.438182868,6.71316767181189e-19,DB0031610022061_,41.84504585,1.190573517,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,162067,DB01118,10018867,18,3045,42,4667,0.145994817,0.656895482,0.355223566,1.168713359,0.278440993,DB0111810018867_,1.278549116,-0.420230357,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,amiodarone,DB01118
,162075,DB00343,10035226,20,8716,41,5054,1.6698251997036e-06,0.282882022,0.156829047,0.494670557,2.26419166232701e-05,DB0034310035226_,10.69570765,-1.262725352,male,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,diltiazem,DB00343
,162099,DB00264,10003246,157,29450,83,24809,0.000554644,1.593458456,1.212936232,2.1061466,0.003363436,DB0026410003246_,5.694792159,0.465906784,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,162101,DB00904,10003246,90,22979,30,14426,0.002490922,1.883339015,1.232802623,2.951548827,0.011627968,DB0090410003246_,4.45434201,0.633046273,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,162118,DB00904,10022061,72,22997,13,14443,5.1616153816088e-06,3.478259107,1.910367578,6.84948022,6.09082201147418e-05,DB0090410022061_,9.706142415,1.246531912,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,162131,DB00904,10022095,45,23024,9,14447,0.000672246,3.137282428,1.513817797,7.302125273,0.003961883,DB0090410022095_,5.531035907,1.143356956,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,162133,DB00126,10042209,75,10096,8,5937,2.99473291352087e-08,5.511743449,2.656067597,13.24338319,6.04814096288099e-07,DB0012610042209_,14.3183447,1.706880988,female,10042209,Stress,10037175,Psychiatric disorders,Psych,ascorbic acid,DB00126
,162169,DB00338,10061218,66,33608,24,22248,0.012736534,1.820436846,1.125194881,3.038607437,0.043175109,DB0033810061218_,3.142491132,0.599076498,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,162173,DB00722,10061218,39,25364,21,26011,0.019365615,1.90448008,1.092840037,3.40864871,0.060271766,DB0072210061218_,2.80889151,0.644209047,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,162218,DB00316,10022694,49,65425,27,36926,1,1.024285691,0.627681541,1.704715972,1,DB0031610022694_,0,0.023995483,NA,10022694,Intestinal perforation,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,162224,DB00115,10041101,39,18386,26,10446,0.521170874,0.852236036,0.505491609,1.458974888,0.680064167,DB0011510041101_,0.385568122,-0.159891752,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,162239,DB00959,10005483,32,8046,49,4953,7.38892663209671e-05,0.402041746,0.248819169,0.641495375,0.000614711,DB0095910005483_,7.39435834,-0.911199351,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,methylprednisolone,DB00959
,162243,DB00231,10012174,50,3246,25,2114,0.341074605,1.302464297,0.787858307,2.20436508,0.510275426,DB0023110012174_,0.672804649,0.264258083,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,temazepam,DB00231
,162249,DB01390,10012174,34,1375,33,1484,0.711411731,1.111936977,0.664175336,1.86347954,0.828032474,DB0139010012174_,0.188702906,0.106103519,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,sodium bicarbonate,DB01390
,162250,DB00046,10012735,222,5237,161,4531,0.094873219,1.192973363,0.965566956,1.476427035,0.203015635,DB0004610012735_,1.594472285,0.176448815,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,insulin lispro,DB00046
,162267,DB01015,10020993,22,9865,35,9346,0.062860157,0.595522584,0.332519733,1.044901661,0.148699927,DB0101510020993_,1.905824918,-0.518315966,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,sulfamethoxazole,DB01015
,162269,DB01132,10020993,26,1259,31,1499,1,0.998591281,0.566231247,1.748334403,1,DB0113210020993_,0,-0.001409712,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,pioglitazone,DB01132
,162326,DB00046,10048294,34,5425,38,4654,0.286556654,0.767601313,0.467906711,1.254674743,0.451337247,DB0004610048294_,0.795540444,-0.264484804,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,insulin lispro,DB00046
,162332,DB00688,10048294,45,6445,43,5335,0.520352264,0.866286567,0.556574337,1.349902889,0.67943962,DB0068810048294_,0.38648691,-0.143539517,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,mycophenolate mofetil,DB00688
,162384,DB01075,10064355,44,19904,21,11076,0.606408536,1.165914762,0.678216361,2.065431932,0.749333538,DB0107510064355_,0.288571083,0.153505982,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,162404,DB00921,10022086,167,5678,290,4613,6.00143021244259e-15,0.467878788,0.382867072,0.570317193,3.64313148115597e-13,DB0092110022086_,28.6407626,-0.759546017,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,162408,DB00852,10033371,62,1104,13,458,0.026027811,1.977830048,1.063248232,3.960300702,0.075775712,DB0085210033371_,2.579977453,0.682000309,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,pseudoephedrine,DB00852
,162453,DB01591,10033371,66,1889,14,642,0.117491659,1.602026706,0.883172757,3.11073714,0.237394746,DB0159110033371_,1.43803093,0.471269519,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,solifenacin,DB01591
,162459,DB00230,10056819,62,19612,11,8640,0.00320034,2.483014468,1.29548655,5.231844678,0.014261412,DB0023010056819_,4.250197842,0.909473333,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,162468,DB00584,10008479,34,2047,23,1851,0.349776512,1.336617735,0.761520312,2.386032493,0.519369315,DB0058410008479_,0.65514006,0.290142344,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,enalapril,DB00584
,162476,DB00158,10001551,45,16770,32,8072,0.112366011,0.676875339,0.420409357,1.101438441,0.229624148,DB0015810001551_,1.471311448,-0.390268161,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,folic acid,DB00158
,162479,DB01175,10001551,48,10676,19,4873,0.692579497,1.153104535,0.664453953,2.079621859,0.814826761,DB0117510001551_,0.204779751,0.1424579,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,escitalopram,DB01175
,162481,DB00158,10003481,41,16774,29,8075,0.124951582,0.680596084,0.41249745,1.136476562,0.248522746,DB0015810003481_,1.392220906,-0.384786271,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,folic acid,DB00158
,162511,DB08935,10035664,24,508,42,771,0.608630385,0.867383123,0.495857874,1.486381397,0.751196191,DB0893510035664_,0.286088422,-0.142274504,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,obinutuzumab,DB08935
,162530,DB00722,10037867,42,25361,29,26003,0.122027867,1.484918385,0.903101803,2.472751241,0.244334602,DB0072210037867_,1.409216672,0.395359811,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,162531,DB01234,10037867,55,31570,38,32850,0.061195893,1.506032737,0.977856233,2.341395191,0.145627997,DB0123410037867_,1.926699878,0.409478867,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,162568,DB00722,10030041,47,25356,42,25990,0.526504473,1.147024258,0.740061911,1.783038961,0.684304436,DB0072210030041_,0.379352379,0.137170987,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,lisinopril,DB00722
,162574,DB00177,10007882,37,4763,24,2826,0.790589748,0.914719317,0.531592767,1.6018622,0.886565478,DB0017710007882_,0.120400295,-0.089138018,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,valsartan,DB00177
,162590,DB00193,10038428,47,19273,45,8657,0.000400437,0.469144401,0.304750175,0.723002558,0.002565004,DB0019310038428_,5.965795377,-0.756844667,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,tramadol,DB00193
,162592,DB00182,10013654,175,5019,328,2524,1.9123237000168e-44,0.268357401,0.22069275,0.325493947,8.78686690223073e-42,DB0018210013654_,94.5353157,-1.3154356,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,162624,DB01229,10009887,36,5705,20,2689,0.567003276,0.848442786,0.477101327,1.550002247,0.718223154,DB0122910009887_,0.330974958,-0.164352627,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,paclitaxel,DB01229
,162637,DB05676,10028411,269,46860,120,25209,0.098255882,1.205902883,0.968359101,1.509010336,0.208253506,DB0567610028411_,1.568999165,0.187228567,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,162653,DB00169,10062237,107,38584,92,18083,2.55708164497255e-05,0.545056747,0.408429823,0.728708574,0.000246111,DB0016910062237_,8.309728247,-0.606865367,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,162657,DB00028,10019303,83,13375,31,5584,0.680290769,1.117800844,0.730839134,1.749783739,0.80660187,DB0002810019303_,0.214925079,0.111363223,NA,10019303,Heart rate increased,10022891,Investigations,Inv,human immunoglobulin g,DB00028
,162679,DB01137,10005750,42,7730,19,5574,0.092473681,1.593925005,0.905705904,2.905123567,0.199178162,DB0113710005750_,1.613555566,0.466199531,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,levofloxacin,DB01137
,162690,DB00678,10052904,87,15512,47,10677,0.187290993,1.274086029,0.882750946,1.859182146,0.333136285,DB0067810052904_,1.099203608,0.242229081,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,162691,DB01137,10052904,43,7729,16,5577,0.024021442,1.939114374,1.068948616,3.691882534,0.071283818,DB0113710052904_,2.64108594,0.662231361,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,162692,DB01224,10052904,31,8077,26,5891,0.594279353,0.869626453,0.499058659,1.5266222,0.740174034,DB0122410052904_,0.30086994,-0.139691524,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,quetiapine,DB01224
,162708,DB00697,10003246,45,6051,8,1798,0.248942957,1.671280873,0.77786789,4.112607782,0.408379555,DB0069710003246_,0.895558254,0.513590322,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,tizanidine,DB00697
,162712,DB00722,10005191,87,25316,58,25974,0.012345011,1.538964829,1.090837585,2.185093778,0.042103102,DB0072210005191_,3.16763385,0.431110002,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,162713,DB00761,10005191,50,15257,25,8600,0.718105443,1.127363356,0.68378877,1.903200373,0.833522203,DB0076110005191_,0.182094939,0.119881593,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,potassium chloride,DB00761
,162718,DB00761,10005557,108,15199,69,8556,0.432239878,0.881119346,0.644632269,1.211252633,0.600680852,DB0076110005557_,0.509691513,-0.126562195,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,potassium chloride,DB00761
,162741,DB09140,10006451,135,3606,12,1786,2.59762461662048e-12,5.571397032,3.075973171,11.08226248,1.09333167410519e-10,DB0914010006451_,22.93662131,1.717645836,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,oxygen,DB09140
,162774,DB00619,10042674,40,2859,20,2474,0.050397702,1.730500453,0.984996144,3.133486201,0.125772951,DB0061910042674_,2.073276973,0.548410646,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,162788,DB05676,10016173,252,46877,80,25249,2.34531095726469e-05,1.696648363,1.313704946,2.211122192,0.000228829,DB0567610016173_,8.382536111,0.528654754,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,apremilast,DB05676
,162791,DB00476,10054196,1083,16174,376,5801,0.623497669,1.033085729,0.91424304,1.16922993,0.763522851,DB0047610054196_,0.269812226,0.032550177,NA,10054196,Affect lability,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,162797,DB00230,10022000,224,19450,73,8578,0.026483035,1.353332141,1.033391778,1.789747394,0.076820236,DB0023010022000_,2.566287189,0.302569804,NA,10022000,Influenza,10021881,Infections and infestations,Infec,pregabalin,DB00230
,162798,DB00476,10022000,162,17095,53,6124,0.64079634,1.094972486,0.79719109,1.525012906,0.777660072,DB0047610022000_,0.251465776,0.090729236,NA,10022000,Influenza,10021881,Infections and infestations,Infec,duloxetine,DB00476
,162804,DB00921,10054112,32,5813,39,4864,0.121114698,0.686591409,0.415717409,1.126549347,0.243015254,DB0092110054112_,1.414631064,-0.37601591,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,buprenorphine,DB00921
,162806,DB01115,10013573,146,3454,43,2225,3.01079341050429e-06,2.18694675,1.539758691,3.162388147,3.80291709731404e-05,DB0111510013573_,10.17715704,0.782506393,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,nifedipine,DB01115
,162809,DB13961,10046306,91,9366,39,6375,0.015294538,1.588145319,1.078483062,2.377644887,0.050079967,DB1396110046306_,2.994134218,0.462566869,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,fish oil,DB13961
,162810,DB06285,10021097,43,8807,7,1099,0.496375392,0.766573586,0.340782768,2.024622354,0.658576064,DB0628510021097_,0.417675254,-0.265824583,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,teriparatide,DB06285
,162824,DB11089,10034474,35,10140,22,8385,0.352014858,1.315538636,0.749738019,2.356057121,0.521756877,DB1108910034474_,0.650553553,0.274246191,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,docusate,DB11089
,162833,DB00646,10048959,57,3396,32,1968,0.912270604,1.032239533,0.655574685,1.651016796,0.960594091,DB0064610048959_,0.040203341,0.031730746,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,162862,DB00973,10000087,70,3781,25,2996,0.000524402,2.218396574,1.383251207,3.665967015,0.003210411,DB0097310000087_,5.741356432,0.796784671,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ezetimibe,DB00973
,162872,DB00051,10050256,43,25688,13,11407,0.248584477,1.46882651,0.774905816,2.978446719,0.407969716,DB0005110050256_,0.896562332,0.384463789,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,162888,DB06643,10012318,156,52265,22,7493,1,1.01659229,0.647660239,1.670068413,1,DB0664310012318_,0,0.016456142,NA,10012318,Dental caries,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,162958,DB00678,10040979,38,15561,38,10686,0.102941972,0.686741516,0.426039233,1.106976606,0.215397637,DB0067810040979_,1.535269485,-0.375797308,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,162973,DB00065,10005750,44,9420,18,4939,0.422995712,1.281665047,0.724646521,2.359353606,0.591894503,DB0006510005750_,0.524426864,0.248160051,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,infliximab,DB00065
,162980,DB00188,10008531,26,7860,55,8773,0.007128797,0.527659407,0.317298483,0.856848593,0.027186133,DB0018810008531_,3.605048255,-0.639304266,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,162986,DB00787,10044565,160,16840,142,17106,0.248151794,1.144553195,0.906377151,1.446535787,0.407501322,DB0078710044565_,0.897711102,0.135014338,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,162987,DB09153,10044565,58,7741,36,5663,0.464805096,1.178593132,0.763317926,1.842008943,0.631757386,DB0915310044565_,0.459249842,0.164321466,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,162989,DB00787,10061822,135,16865,107,17141,0.061177197,1.282317098,0.986686018,1.669987098,0.145609872,DB0078710061822_,1.926824342,0.248668674,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,163006,DB00381,10021519,45,29315,33,22854,0.820225311,1.063104523,0.663217247,1.720270889,0.904288487,DB0038110021519_,0.100606847,0.061193422,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,163019,DB06228,10028024,54,15858,49,16027,0.622267438,1.113781146,0.741987099,1.675509666,0.762460359,DB0622810028024_,0.27120476,0.107760664,NA,10028024,Mouth haemorrhage,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,163041,DB00863,10006002,59,10614,14,5826,0.003082628,2.313108599,1.274533575,4.490324826,0.013833015,DB0086310006002_,4.280697133,0.838592334,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,163047,DB06228,10000060,80,15832,48,16028,0.004428868,1.687261815,1.164417394,2.467877345,0.018534119,DB0622810000060_,3.988141982,0.523106987,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,163050,DB00186,10017944,81,16820,31,9977,0.039457814,1.549852924,1.012111283,2.428325192,0.104561814,DB0018610017944_,2.257976856,0.438160039,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,163052,DB06605,10031161,41,14032,13,13020,0.000341891,2.926069459,1.536397019,5.954641015,0.002249664,DB0660510031161_,6.096974601,1.073660041,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,163068,DB00490,10033295,85,3985,18,1558,0.019324473,1.846055808,1.096428657,3.274401108,0.060172218,DB0049010033295_,2.810544532,0.613051368,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,buspirone,DB00490
,163076,DB01015,10035759,31,9856,19,9362,0.156364091,1.549759838,0.847585872,2.905695829,0.292518425,DB0101510035759_,1.229227624,0.438099975,NA,10035759,Pneumothorax,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,163080,DB00864,10041349,30,6839,31,8361,0.521798089,1.183094,0.691088416,2.022801452,0.680482388,DB0086410041349_,0.384953338,0.168133041,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,tacrolimus,DB00864
,163081,DB00285,10047513,95,10856,14,3704,0.001837468,2.315263312,1.312170408,4.40070083,0.009075131,DB0028510047513_,4.702217499,0.839523423,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,venlafaxine,DB00285
,163082,DB00490,10047513,37,4033,19,1557,0.299071213,0.751847463,0.419995244,1.388616041,0.465042997,DB0049010047513_,0.765625411,-0.285221818,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,buspirone,DB00490
,163083,DB00787,10047513,129,16871,75,17173,0.000103738,1.750748911,1.305956478,2.361356805,0.000823671,DB0078710047513_,7.101739185,0.560043645,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,acyclovir,DB00787
,163103,DB00231,10000087,32,3264,22,2117,0.888912495,0.943418074,0.529774385,1.709104159,0.953911952,DB0023110000087_,0.047183905,-0.05824575,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,temazepam,DB00231
,163128,DB00480,10018304,55,67373,39,67623,0.099516365,1.415479489,0.922067132,2.191682566,0.210102227,DB0048010018304_,1.560161072,0.347468335,NA,10018304,Glaucoma,10015919,Eye disorders,Eye,lenalidomide,DB00480
,163134,DB00008,10013709,40,1485,74,1602,0.00728339,0.583226952,0.38408915,0.874361034,0.027619061,DB0000810013709_,3.589249125,-0.539178885,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,peginterferon alfa-2a,DB00008
,163147,DB00787,10017533,43,16957,24,17224,0.019716544,1.819834679,1.079342655,3.13703575,0.06111071,DB0078710017533_,2.79506815,0.598745661,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,acyclovir,DB00787
,163156,DB00787,10062355,176,16824,174,17074,0.829921307,1.026529422,0.826778688,1.274592649,0.910731198,DB0078710062355_,0.093507487,0.02618362,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,163163,DB00813,10061623,53,10519,48,10120,0.765980503,1.062304764,0.704449694,1.605466646,0.870989683,DB0081310061623_,0.138125147,0.060440854,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,163186,DB00190,10019075,83,3214,128,4546,0.571342534,0.917165782,0.684625715,1.22323261,0.72156175,DB0019010019075_,0.326337319,-0.086467036,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,163194,DB00915,10070863,22,1433,32,1019,0.011575055,0.489013681,0.269022392,0.873924879,0.040035572,DB0091510070863_,3.217986925,-0.715364812,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,amantadine,DB00915
,163198,DB00697,10013754,62,6034,25,1781,0.199091112,0.732030194,0.451790129,1.219553632,0.347923002,DB0069710013754_,1.055774084,-0.311933517,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,163203,DB00697,10047513,71,6025,21,1785,1,1.001659576,0.606324982,1.721492463,1,DB0069710047513_,0,0.0016582,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,tizanidine,DB00697
,163241,DB14500,10047942,137,7672,79,3994,0.470260049,0.902813729,0.677603156,1.209752266,0.63651409,DB1450010047942_,0.451748724,-0.102239027,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,potassium,DB14500
,163275,DB01229,10013700,60,5681,9,2700,0.000394263,3.168122597,1.559396635,7.273752354,0.002532245,DB0122910013700_,5.978648923,1.153139172,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,paclitaxel,DB01229
,163302,DB00557,10053762,166,5821,89,2978,0.737371682,0.954219239,0.730286184,1.253686739,0.848609412,DB0055710053762_,0.164156256,-0.046861824,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxyzine,DB00557
,163313,DB00563,10036790,98,46548,49,15299,0.021185416,0.657348168,0.461680439,0.946665245,0.064720904,DB0056310036790_,2.737671036,-0.419541465,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,163315,DB09140,10028810,158,3583,38,1760,4.76666627665947e-05,2.042162958,1.418137048,3.006354821,0.000424071,DB0914010028810_,7.765609296,0.71400952,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,oxygen,DB09140
,163322,DB00112,10028116,49,5884,51,4040,0.040812579,0.659725875,0.435517194,0.998344608,0.107265138,DB0011210028116_,2.232451581,-0.415930871,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,163324,DB00433,10028116,47,7609,28,5992,0.293814758,1.321827866,0.809681001,2.194809698,0.459547227,DB0043310028116_,0.777513564,0.279015525,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,163328,DB00433,10033553,43,7613,20,6000,0.056039871,1.694404401,0.974235377,3.043977786,0.136169747,DB0043310033553_,1.993853033,0.527331293,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,prochlorperazine,DB00433
,163332,DB01234,10033553,44,31581,18,32870,0.000533834,2.544247,1.439924706,4.679802779,0.0032564,DB0123410033553_,5.72713313,0.933834732,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,163334,DB01394,10003988,45,1395,25,1978,0.000191612,2.551567579,1.523312461,4.364503428,0.001389191,DB0139410003988_,6.57903404,0.936707907,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,colchicine,DB01394
,163343,DB01394,10016256,111,1329,94,1909,0.000254492,1.695882565,1.264975189,2.277505791,0.001762668,DB0139410016256_,6.340926973,0.528203292,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,colchicine,DB01394
,163363,DB00820,10064355,47,11868,34,5782,0.095981644,0.673472328,0.423576664,1.08109961,0.204762398,DB0082010064355_,1.585905007,-0.395308371,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,tadalafil,DB00820
,163369,DB09146,10013700,123,665,89,338,0.02645712,0.70262228,0.513787046,0.963337624,0.076770481,DB0914610013700_,2.566935081,-0.352935829,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,iron sucrose,DB09146
,163401,DB01234,10056819,113,31512,76,32812,0.003464068,1.548159664,1.146889857,2.099608482,0.015196672,DB0123410056819_,4.186678838,0.437066912,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,163402,DB00982,10025482,37,3327,14,2087,0.113197689,1.657698462,0.872792743,3.327708009,0.230892893,DB0098210025482_,1.465801343,0.505430172,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,isotretinoin,DB00982
,163415,DB00252,10003549,30,2202,31,1877,0.518083449,0.824950937,0.48043107,1.414742906,0.677438866,DB0025210003549_,0.389435965,-0.192431364,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,phenytoin,DB00252
,163416,DB00252,10010305,42,2190,39,1869,0.736379441,0.919091863,0.577357939,1.46616153,0.847745865,DB0025210010305_,0.165174375,-0.084369202,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,phenytoin,DB00252
,163436,DB01263,10012735,36,588,19,846,0.000416609,2.724254087,1.504601936,5.079999918,0.002649864,DB0126310012735_,5.933247109,1.002194661,female,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,posaconazole,DB01263
,163460,DB00656,10023676,21,11992,31,6588,0.000422799,0.372171229,0.20308629,0.669367608,0.002681773,DB0065610023676_,5.921277235,-0.988401236,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,trazodone,DB00656
,163465,DB01234,10023676,30,31595,36,32852,0.622808943,0.866489815,0.515337925,1.447319792,0.762963814,DB0123410023676_,0.270544675,-0.143304924,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,163504,DB00656,10037423,56,11957,29,6590,0.821302596,1.064274866,0.667373162,1.730476621,0.904756344,DB0065610037423_,0.100089605,0.06229369,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,163512,DB00099,10038695,24,2361,33,1922,0.060034991,0.592125626,0.333618935,1.036655789,0.143521578,DB0009910038695_,1.941269887,-0.52403646,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,filgrastim,DB00099
,163514,DB00537,10038695,49,7508,44,4254,0.030054421,0.630977139,0.410591211,0.972307484,0.084825562,DB0053710038695_,2.46715834,-0.460485648,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ciprofloxacin,DB00537
,163518,DB00207,10040070,35,9045,29,5426,0.19842942,0.724041015,0.429392425,1.229432729,0.347216809,DB0020710040070_,1.057805884,-0.322907238,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,azithromycin,DB00207
,163545,DB01220,10033371,35,1259,18,1118,0.069956511,1.726298364,0.945376972,3.257249456,0.161214001,DB0122010033371_,1.825022598,0.545979442,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,rifaximin,DB01220
,163552,DB00091,10005483,27,5483,30,2640,0.002536396,0.433382931,0.247339417,0.755994631,0.011793591,DB0009110005483_,4.440199067,-0.836133575,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,cyclosporine,DB00091
,163562,DB00213,10006451,230,18665,77,13344,2.06297583826042e-09,2.135415583,1.64124464,2.804215186,5.37416451027503e-08,DB0021310006451_,16.73907762,0.75866128,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,163563,DB00455,10006451,143,9258,38,5080,3.04283206920426e-05,2.064807082,1.432447785,3.041245915,0.000287391,DB0045510006451_,8.15466783,0.725036799,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,loratadine,DB00455
,163564,DB00476,10020642,1071,16186,366,5811,0.43993118,1.050547167,0.928492114,1.190705557,0.608273905,DB0047610020642_,0.497129997,0.04931114,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,duloxetine,DB00476
,163569,DB00230,10029883,48,19626,12,8639,0.091400655,1.760694372,0.92077783,3.643399921,0.197506266,DB0023010029883_,1.621984966,0.565708261,NA,10029883,Obesity,10027433,Metabolism and nutrition disorders,Metab,pregabalin,DB00230
,163578,DB09033,10019211,143,2481,61,1608,0.007921937,1.519234662,1.110287862,2.099540189,0.029552672,DB0903310019211_,3.521581126,0.418206696,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,vedolizumab,DB09033
,163580,DB01255,10001488,13,2120,64,1514,2.42663295198385e-13,0.145154718,0.07302826,0.267339518,1.18778486299619e-11,DB0125510001488_,25.15634591,-1.929955084,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,lisdexamfetamine,DB01255
,163581,DB01255,10001497,21,2112,35,1543,0.002624449,0.438447148,0.241490899,0.777928705,0.012123662,DB0125510001497_,4.412596163,-0.824516003,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,lisdexamfetamine,DB01255
,163591,DB00571,10022437,95,5028,52,2557,0.660804881,0.929095852,0.65337651,1.333829089,0.792989993,DB0057110022437_,0.231944677,-0.073543368,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,propranolol,DB00571
,163598,DB09037,10037660,73,2453,92,2743,0.476452836,0.88730807,0.640231574,1.225968531,0.641839011,DB0903710037660_,0.443417768,-0.11956304,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,pembrolizumab,DB09037
,163637,DB00331,10047531,48,24898,38,20714,0.829478325,1.0508996,0.672063228,1.653788106,0.910519212,DB0033110047531_,0.09374028,0.049646559,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,metformin,DB00331
,163640,DB00227,10048959,51,2416,27,1776,0.202968385,1.388416074,0.850661242,2.312439421,0.352542391,DB0022710048959_,1.042584406,0.328163582,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,lovastatin,DB00227
,163643,DB00678,10037377,80,15519,78,10646,0.028390935,0.703611026,0.508054819,0.974773637,0.081145623,DB0067810037377_,2.511509929,-0.351529595,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,163645,DB01306,10051055,13,4195,37,3829,0.000289354,0.320739098,0.156197926,0.618500315,0.001958459,DB0130610051055_,6.235597253,-1.137127265,male,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,insulin aspart,DB01306
,163647,DB00451,10000496,76,47195,35,15384,0.097715223,0.707817958,0.468173298,1.089193678,0.207442122,DB0045110000496_,1.57290291,-0.34556834,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,163655,DB00451,10006811,54,47217,8,15411,0.037538064,2.202948927,1.041745991,5.361883011,0.100646506,DB0045110006811_,2.296140845,0.789796884,NA,10006811,Bursitis,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,163672,DB06724,10027175,80,7849,24,3895,0.028208464,1.654074464,1.035137973,2.734664497,0.080711858,DB0672410027175_,2.516869778,0.503241616,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,163677,DB00924,10060933,39,10123,11,4240,0.279329377,1.485014445,0.744972344,3.217901752,0.443150221,DB0092410060933_,0.813846467,0.395424499,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,163689,DB00115,10001053,52,18373,37,10435,0.320436969,0.798224125,0.513299891,1.252469043,0.488611541,DB0011510001053_,0.7161875,-0.225365862,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,163764,DB00126,10005725,23,10148,32,5913,0.001780984,0.418819054,0.233787039,0.739241393,0.008841848,DB0012610005725_,4.728259402,-0.870316303,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,ascorbic acid,DB00126
,163778,DB00497,10005734,42,19225,33,16342,0.816798253,1.081893379,0.669116221,1.762611639,0.901922933,DB0049710005734_,0.103226203,0.078712635,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,oxycodone,DB00497
,163789,DB01592,10006451,79,6197,20,3047,0.00688487,1.942052315,1.174536222,3.356391128,0.026454008,DB0159210006451_,3.632347617,0.663745308,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,iron,DB01592
,163851,DB00126,10009887,35,10136,16,5929,0.469185197,1.279561248,0.689090714,2.478071557,0.635501025,DB0012610009887_,0.453341575,0.246517244,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,163852,DB00158,10009887,44,16771,25,8079,0.521143385,0.847852325,0.507212195,1.446669863,0.680064167,DB0015810009887_,0.385568122,-0.165048803,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,163853,DB00381,10009887,82,29278,50,22837,0.187766532,1.279201982,0.888758069,1.857353354,0.333791647,DB0038110009887_,1.097238292,0.246236432,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,163854,DB00588,10009887,43,16481,15,8453,0.213827215,1.470273794,0.800194907,2.850899685,0.366009921,DB0058810009887_,1.00509484,0.385448638,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,163857,DB01015,10009887,39,9848,51,9330,0.13939938,0.724498459,0.464442653,1.122328062,0.269014551,DB0101510009887_,1.312989807,-0.322275645,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,163861,DB11089,10009887,58,10117,33,8374,0.091448151,1.454741511,0.931968552,2.305308703,0.197584534,DB1108910009887_,1.621588765,0.374828229,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,163865,DB11750,10012735,268,2232,167,1346,0.753527192,0.967748812,0.785167952,1.195354323,0.86133778,DB1175010012735_,0.14926854,-0.032782717,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,clobetasol,DB11750
,163867,DB00126,10021015,37,10134,20,5925,0.890793048,1.081635125,0.611073326,1.968787554,0.954680373,DB0012610021015_,0.046378682,0.078473901,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,ascorbic acid,DB00126
,163868,DB00158,10021015,33,16782,23,8081,0.198171344,0.690882348,0.3933168,1.233161434,0.346857584,DB0015810021015_,1.058841004,-0.369785733,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,folic acid,DB00158
,163869,DB00196,10021015,42,5041,29,3256,0.80774415,0.9354546,0.567827007,1.56049014,0.896255547,DB0019610021015_,0.109529698,-0.066722665,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,fluconazole,DB00196
,163902,DB00186,10021027,46,16855,7,10001,0.000162093,3.89903232,1.747550635,10.24015886,0.001204754,DB0018610021027_,6.721479917,1.360728399,female,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,lorazepam,DB00186
,163918,DB00338,10024378,62,33612,63,22209,0.017266031,0.650281575,0.450286245,0.938815001,0.055064017,DB0033810024378_,2.89925882,-0.430349818,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,omeprazole,DB00338
,163960,DB00627,10037660,16,1313,39,1560,0.014005127,0.487555976,0.253131463,0.897613197,0.046603969,DB0062710037660_,3.066069568,-0.718350173,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,niacin,DB00627
,163968,DB14500,10038435,73,7736,38,4035,1,1.001996653,0.666727536,1.527544613,1,DB1450010038435_,0,0.001994662,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,potassium,DB14500
,163972,DB00295,10039020,25,14638,41,9561,0.000225464,0.398283535,0.231947422,0.671283401,0.001593741,DB0029510039020_,6.441671326,-0.920591128,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,163977,DB00904,10039020,26,23043,33,14423,0.00718622,0.493146819,0.283151533,0.850572319,0.02734561,DB0090410039020_,3.599199276,-0.706948342,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,163984,DB11089,10039020,16,10159,36,8371,0.000664167,0.366239816,0.189584593,0.67758837,0.00392659,DB1108910039020_,5.539983937,-1.004466924,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,163988,DB01592,10040047,61,6215,54,3013,0.001815571,0.547649933,0.372431092,0.807298276,0.00898471,DB0159210040047_,4.712231079,-0.602119004,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,iron,DB01592
,163991,DB00158,10040943,45,16770,14,8090,0.165491616,1.550575377,0.835232971,3.060671661,0.304788896,DB0015810040943_,1.188135888,0.438626073,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,163992,DB00169,10040943,62,38629,31,18144,0.823952951,0.939399982,0.600782633,1.496618844,0.906706996,DB0016910040943_,0.097935928,-0.062513924,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,163994,DB00295,10040943,30,14633,20,9582,1,0.982226553,0.539293787,1.825979389,1,DB0029510040943_,0,-0.017933291,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,morphine,DB00295
,163995,DB00338,10040943,63,33611,38,22234,0.685162416,1.096729614,0.721602303,1.686864229,0.809887557,DB0033810040943_,0.210859859,0.092332674,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,163996,DB00381,10040943,53,29307,45,22842,0.684627858,0.91796702,0.605065672,1.398040177,0.809548033,DB0038110040943_,0.21127917,-0.085593815,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,163997,DB00588,10040943,35,16489,20,8448,0.671891572,0.896605386,0.503119294,1.640146763,0.800864773,DB0058810040943_,0.222063169,-0.10913944,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,164001,DB00904,10040943,48,23021,14,14442,0.00892925,2.150835462,1.165915751,4.225839919,0.032507665,DB0090410040943_,3.426279363,0.765856354,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,164002,DB00999,10040943,41,21389,25,12214,0.798809933,0.936510102,0.555744457,1.607823061,0.891356522,DB0099910040943_,0.115010795,-0.06559497,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,hydrochlorothiazide,DB00999
,164005,DB01373,10040943,43,22677,17,7364,0.547548895,0.821375367,0.458495276,1.53717498,0.702184407,DB0137310040943_,0.353559222,-0.196775066,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,164039,DB00381,10041349,316,29044,202,22685,0.029124431,1.221845159,1.019941592,1.466408801,0.08276956,DB0038110041349_,2.491694921,0.200362142,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,164045,DB00115,10052428,37,18388,23,10449,0.788310526,0.914147494,0.528680703,1.612357626,0.885341847,DB0011510052428_,0.12178144,-0.089763348,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,164047,DB00158,10052428,35,16780,17,8087,1,0.992235407,0.540793264,1.889866057,1,DB0015810052428_,0,-0.007794894,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,164049,DB00338,10052428,46,33628,31,22241,1,0.981401361,0.608889965,1.601566797,1,DB0033810052428_,0,-0.018773768,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,164051,DB00563,10052428,62,46584,12,15336,0.105033916,1.700848126,0.907483372,3.468888306,0.218574656,DB0056310052428_,1.520627648,0.531127024,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,164052,DB00588,10052428,43,16481,14,8454,0.161290376,1.575475901,0.844876691,3.119918708,0.299210779,DB0058810052428_,1.206607007,0.454557386,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,164055,DB00722,10052428,37,25366,27,26005,0.210814608,1.404875731,0.832287556,2.399940661,0.362221334,DB0072210052428_,1.015499834,0.339948851,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,164056,DB00904,10052428,42,23027,14,14442,0.039309815,1.881497818,1.006840743,3.73144566,0.104263727,DB0090410052428_,2.260831757,0.632068171,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,164058,DB00996,10052428,63,38890,37,22388,0.917564864,0.980193999,0.642801371,1.513909594,0.963386915,DB0099610052428_,0.037300167,-0.020004768,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,164061,DB01373,10052428,40,22680,11,7370,0.745175424,1.181648209,0.594633672,2.554711337,0.854485157,DB0137310052428_,0.157256147,0.166910251,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,164119,DB00169,10061922,20,38671,30,18145,5.12167065632621e-05,0.31281684,0.168357133,0.569541262,0.000451225,DB0016910061922_,7.703543453,-1.162137436,male,10061922,Pulmonary function test decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,164195,DB00169,10067973,31,38660,22,18153,0.141987748,0.661642007,0.370841204,1.199739766,0.272578728,DB0016910067973_,1.299827795,-0.413030644,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,cholecalciferol,DB00169
,164197,DB00381,10067973,48,29312,41,22846,0.670421108,0.912479591,0.588648907,1.420221389,0.800083838,DB0038110067973_,0.22303876,-0.09158956,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,amlodipine,DB00381
,164229,DB09140,10020937,44,3697,18,1780,0.68256335,1.176882142,0.664010974,2.170608793,0.807997372,DB0914010020937_,0.213196472,0.162868689,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,oxygen,DB09140
,164246,DB05676,10024264,45,47084,47,25282,0.002000141,0.514095075,0.333818209,0.790980379,0.009723268,DB0567610024264_,4.633233525,-0.66534706,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,164251,DB00480,10018838,85,67343,65,67597,0.102590159,1.312617906,0.939017413,1.842208302,0.214909929,DB0048010018838_,1.537536273,0.272023544,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,164265,DB06228,10022437,128,15784,76,16000,0.000188785,1.707219068,1.274290732,2.300519262,0.001373053,DB0622810022437_,6.590718391,0.534865771,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,rivaroxaban,DB06228
,164278,DB00678,10029331,202,15397,115,10609,0.107538673,1.210273938,0.956542321,1.537378446,0.22246608,DB0067810029331_,1.502980639,0.190846729,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,losartan,DB00678
,164281,DB06228,10029331,104,15808,106,15970,1,0.991186382,0.748219422,1.312840185,1,DB0622810029331_,0,-0.008852687,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,164283,DB00678,10038153,73,15526,34,10690,0.061307066,1.478276058,0.970512796,2.292737923,0.145846342,DB0067810038153_,1.925201663,0.390876583,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,losartan,DB00678
,164284,DB00706,10038153,10,1065,83,15842,0.085387799,1.792101192,0.826403163,3.476888713,0.187362742,DB0070610038153_,1.674708743,0.583388782,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,tamsulosin,DB00706
,164291,DB00678,10061623,113,15486,76,10648,0.940809821,1.022336459,0.756831417,1.387453436,0.980052954,DB0067810061623_,0.020148674,0.022090653,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,164297,DB01212,10001053,39,1980,25,1916,0.129983858,1.5094139,0.886801881,2.613273985,0.25569718,DB0121210001053_,1.363761427,0.41172143,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ceftriaxone,DB01212
,164302,DB00182,10021097,45,5149,19,2833,0.361221571,1.303089313,0.745197267,2.363936151,0.531124707,DB0018210021097_,0.632758431,0.26473784,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,amphetamine,DB00182
,164312,DB00654,10000059,33,3783,18,2580,0.477441133,1.250284511,0.682133713,2.363839988,0.642759952,DB0065410000059_,0.441983949,0.223371134,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,latanoprost,DB00654
,164315,DB01036,10035664,50,1451,10,412,0.42731578,1.41945528,0.703602858,3.167772004,0.595890008,DB0103610035664_,0.517699178,0.350273192,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,tolterodine,DB01036
,164323,DB00421,10005557,68,8835,57,5195,0.051040811,0.701518138,0.485203664,1.017398836,0.126979739,DB0042110005557_,2.063727744,-0.354508524,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,spironolactone,DB00421
,164325,DB14500,10005557,47,7762,30,4043,0.400122698,0.816059849,0.504562783,1.338590963,0.56999296,DB1450010005557_,0.562131269,-0.203267582,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,potassium,DB14500
,164331,DB00590,10030124,27,749,34,1918,0.00907515,2.033007363,1.170914745,3.498192924,0.032949833,DB0059010030124_,3.412769087,0.709516156,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,doxazosin,DB00590
,164349,DB01234,10013538,107,31518,81,32807,0.033904848,1.374999275,1.020177556,1.859254641,0.093196228,DB0123410013538_,2.37304803,0.318453204,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,164351,DB06643,10013538,43,52378,10,7505,0.208035391,0.616136325,0.304705079,1.375670814,0.358851969,DB0664310013538_,1.024845318,-0.484287033,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,denosumab,DB06643
,164404,DB00887,10037400,67,2274,49,1766,0.776545315,1.06188739,0.719622466,1.5763805,0.878213089,DB0088710037400_,0.129866016,0.060047881,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bumetanide,DB00887
,164407,DB01222,10037423,61,9213,27,5378,0.267789185,1.318796862,0.824390256,2.161187199,0.4301622,DB0122210037423_,0.843592931,0.276719853,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,164410,DB00887,10061818,38,2303,22,1793,0.296058575,1.344672542,0.772119238,2.395996683,0.461902338,DB0088710061818_,0.7724018,0.29615052,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,164419,DB01156,10017885,81,13541,19,6309,0.005037199,1.986223941,1.192647137,3.470708037,0.020585008,DB0115610017885_,3.883192221,0.686235319,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,164429,DB00285,10017944,45,10906,13,3705,0.762205892,1.175941942,0.622576839,2.378836975,0.868285351,DB0028510017944_,0.141234873,0.16206948,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,164430,DB01068,10017944,57,13706,28,6812,1,1.011772023,0.632299097,1.653752056,1,DB0106810017944_,0,0.011703272,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,164432,DB01156,10017944,39,13583,13,6315,0.37079601,1.39476967,0.728171821,2.849817734,0.54048929,DB0115610017944_,0.615280457,0.33272929,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,164441,DB08910,10050584,119,16625,63,17425,9.71404978368734e-06,1.979730283,1.445589149,2.733294037,0.000106014,DB0891010050584_,9.151943002,0.682960615,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,pomalidomide,DB08910
,164442,DB00203,10061224,40,13838,22,8916,0.603775896,1.171429235,0.679178516,2.071041258,0.747337482,DB0020310061224_,0.291238412,0.158224571,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,164443,DB00374,10061224,48,17668,10,5714,0.224162372,1.552298984,0.77487013,3.443662101,0.378721357,DB0037410061224_,0.97095455,0.439737047,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,164451,DB00321,10005750,49,7398,18,2832,1,1.042049815,0.595144829,1.90409791,1,DB0032110005750_,0,0.041189749,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,amitriptyline,DB00321
,164452,DB00390,10005750,37,4108,15,3286,0.025028494,1.972900409,1.054803226,3.876685386,0.073516638,DB0039010005750_,2.610243534,0.679504749,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,digoxin,DB00390
,164454,DB11089,10005750,90,10085,71,8336,0.811641741,1.047777157,0.758000881,1.453074966,0.898803639,DB1108910005750_,0.10669069,0.046670927,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,docusate,DB11089
,164474,DB00341,10042609,37,11368,15,5053,0.880651758,1.096408819,0.586772424,2.152395402,0.950087484,DB0034110042609_,0.05120121,0.092040129,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,cetirizine,DB00341
,164476,DB01076,10042609,92,25655,64,25519,0.030190949,1.429863356,1.027546312,2.000116589,0.085114935,DB0107610042609_,2.46375276,0.357578885,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,atorvastatin,DB01076
,164487,DB01136,10013781,46,9838,29,11086,0.014699708,1.787357773,1.098260469,2.952840231,0.048519096,DB0113610013781_,3.025797835,0.580738425,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,164500,DB01136,10042128,45,9839,35,11080,0.115843088,1.447845352,0.909413631,2.322276542,0.234944678,DB0113610042128_,1.448405204,0.370076487,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,164527,DB00402,10028813,92,1260,31,665,0.038828094,1.565988347,1.019701099,2.462014072,0.103299237,DB0040210028813_,2.270125292,0.448517156,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,eszopiclone,DB00402
,164530,DB00956,10029331,48,5766,53,3414,0.002521631,0.536255315,0.354337632,0.809851763,0.011737395,DB0095610029331_,4.444975394,-0.623144897,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,164532,DB11133,10029331,31,2400,23,1551,0.674405638,0.871066244,0.489612891,1.570640393,0.802533091,DB1113310029331_,0.21998219,-0.13803725,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,omega-3 fatty acids,DB11133
,164533,DB00402,10047700,46,1306,14,682,0.096066997,1.715405847,0.918684407,3.403780619,0.204861351,DB0040210047700_,1.585421865,0.539649698,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,eszopiclone,DB00402
,164534,DB11133,10047700,70,2361,24,1550,0.005347069,1.914505691,1.183097735,3.197955653,0.021581221,DB1113310047700_,3.835931764,0.649459464,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,omega-3 fatty acids,DB11133
,164535,DB00402,10053762,42,1310,20,676,0.891815523,1.08362956,0.616449166,1.964799732,0.955017051,DB0040210053762_,0.046026084,0.08031611,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,eszopiclone,DB00402
,164536,DB11133,10053762,43,2388,31,1543,0.633423669,0.896295591,0.549108233,1.478335417,0.772027317,DB1113310053762_,0.258735344,-0.10948502,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,omega-3 fatty acids,DB11133
,164537,DB00227,10011224,61,2406,34,1769,0.209029633,1.319031889,0.849151503,2.079346638,0.36006284,DB0022710011224_,1.021476706,0.27689805,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lovastatin,DB00227
,164538,DB00868,10011224,149,2835,80,1566,0.887473543,1.028804629,0.773084116,1.377259323,0.953356575,DB0086810011224_,0.047766285,0.028397574,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,benzonatate,DB00868
,164564,DB00264,10060820,50,29557,21,24871,0.008258086,2.003413962,1.181230735,3.512933765,0.030544504,DB0026410060820_,3.488570516,0.694852706,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,164570,DB00341,10064355,53,11352,30,5038,0.28520706,0.78402645,0.491269823,1.27269916,0.449777565,DB0034110064355_,0.799002118,-0.243312522,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,164595,DB06589,10010774,27,2003,41,2612,0.622368157,0.858796881,0.506145596,1.435557553,0.762565995,DB0658910010774_,0.271066223,-0.152222844,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,pazopanib,DB06589
,164634,DB00557,10027599,61,5926,6,3061,3.14762291894093e-06,5.251408038,2.27473401,14.88457318,3.94729334085699e-05,DB0055710027599_,10.13989535,1.658496238,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,164672,DB00215,10020937,149,10954,29,5247,1.59203813413023e-06,2.460972441,1.642211859,3.806080112,2.17216311215226e-05,DB0021510020937_,10.73720197,0.900556573,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,164673,DB00540,10020937,42,2441,18,1073,1,1.025684665,0.574669709,1.902194826,1,DB0054010020937_,0,0.025360355,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,nortriptyline,DB00540
,164685,DB00126,10042609,42,10129,12,5933,0.024147106,2.050019629,1.058522419,4.281144066,0.071572697,DB0012610042609_,2.637041601,0.717849368,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,ascorbic acid,DB00126
,164693,DB00563,10049548,71,46575,9,15339,0.004003382,2.598216324,1.293827975,5.915348091,0.017092323,DB0056310049548_,4.069125854,0.95482518,NA,10049548,Knee operation,10042613,Surgical and medical procedures,Surg,methotrexate,DB00563
,164700,DB00480,10048334,41,67387,33,67629,0.354785913,1.246881414,0.769101563,2.035533518,0.524614521,DB0048010048334_,0.645091533,0.220645565,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,164710,DB14500,10003246,48,7761,9,4064,0.002939761,2.792566521,1.35349655,6.479955918,0.013288327,DB1450010003246_,4.320869334,1.026961073,female,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,164721,DB14500,10013950,55,7754,25,4048,0.637007687,1.148492134,0.702510627,1.926501877,0.774381848,DB1450010013950_,0.255690184,0.138449895,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,164723,DB00335,10028391,45,8421,21,5444,0.255610088,1.385280758,0.807213828,2.451038752,0.416380217,DB0033510028391_,0.876156454,0.325902832,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,164724,DB00927,10028391,42,7455,24,4992,0.614959087,1.171781942,0.692431508,2.025826757,0.756449895,DB0092710028391_,0.27911898,0.158525617,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,famotidine,DB00927
,164725,DB14500,10028391,40,7769,12,4061,0.106639368,1.742320967,0.894905897,3.65252136,0.221092901,DB1450010028391_,1.5091723,0.555218114,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,164734,DB00338,10053156,61,33613,28,22244,0.128789649,1.441698617,0.907188682,2.343473397,0.253914328,DB0033810053156_,1.370758361,0.365822013,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,164737,DB06643,10053156,109,52312,15,7500,1,1.04182858,0.604268789,1.926200594,1,DB0664310053156_,0,0.040977419,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,164767,DB14500,10029354,81,7728,41,4032,0.923811348,1.030751383,0.698054861,1.542704812,0.966829343,DB1450010029354_,0.03373328,0.030288035,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,potassium,DB14500
,164782,DB00722,10040829,88,25315,65,25967,0.051636482,1.388699942,0.99597275,1.944978623,0.12811638,DB0072210040829_,2.05481621,0.328368016,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,164813,DB00374,10065455,36,17680,14,5710,0.514652245,0.830463573,0.436749048,1.668118782,0.67450623,DB0037410065455_,0.393774367,-0.185771212,NA,10065455,Infusion site cellulitis,10021881,Infections and infestations,Infec,treprostinil,DB00374
,164822,DB00635,10073755,91,32962,101,23693,0.003273011,0.647648031,0.482181442,0.868813806,0.014521242,DB0063510073755_,4.232142745,-0.434407892,NA,10073755,Pneumocystis jirovecii pneumonia,10021881,Infections and infestations,Infec,prednisone,DB00635
,164824,DB01234,10073755,89,31536,98,32790,0.714630663,0.944257312,0.700319202,1.271779379,0.830822547,DB0123410073755_,0.185339048,-0.057356574,NA,10073755,Pneumocystis jirovecii pneumonia,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,164836,DB00338,10074902,48,33626,16,22256,0.015105312,1.985577284,1.107549967,3.746752676,0.049596292,DB0033810074902_,3.003839201,0.685909695,NA,10074902,Expired product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,164860,DB00627,10017955,8,1321,42,1557,1.87032552799344e-05,0.224603398,0.090777181,0.486471008,0.000188358,DB0062710017955_,8.577164757,-1.493419106,male,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,niacin,DB00627
,164892,DB01098,10047571,54,8095,32,7177,0.082546375,1.496088908,0.947600269,2.397213374,0.182606587,DB0109810047571_,1.700421241,0.402854308,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,rosuvastatin,DB01098
,164893,DB00043,10028334,69,6344,13,2287,0.031688145,1.913353516,1.04605827,3.780193122,0.088411303,DB0004310028334_,2.425755455,0.64885747,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,omalizumab,DB00043
,164900,DB00338,10022094,52,33622,14,22258,0.001578231,2.458834734,1.342350794,4.80567864,0.008010774,DB0033810022094_,4.826967919,0.899687552,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,164925,DB06724,10013946,75,7854,37,3882,1,1.001899375,0.665805149,1.53124281,1,DB0672410013946_,0,0.001897573,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,164926,DB00863,10074903,43,10630,13,5827,0.067937512,1.813103139,0.956034911,3.678231918,0.157588691,DB0086310074903_,1.847766859,0.595039819,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,164933,DB00341,10018964,32,11373,25,5043,0.042946481,0.567619644,0.325505507,1.000157885,0.111584942,DB0034110018964_,2.192969166,-0.566303725,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,164934,DB00497,10018964,30,19237,50,16325,0.003332899,0.509190419,0.31245386,0.816957229,0.014724676,DB0049710018964_,4.218230574,-0.674933229,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,164957,DB08895,10005483,42,28072,23,6623,0.002218294,0.430839018,0.253025609,0.751104772,0.010586993,DB0889510005483_,4.548129143,-0.842020768,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,tofacitinib,DB08895
,164993,DB00338,10002383,29,33645,41,22231,0.002023167,0.467361535,0.280033708,0.770771813,0.009816141,DB0033810002383_,4.623727198,-0.760652156,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,omeprazole,DB00338
,165036,DB00887,10003988,46,2295,21,1794,0.046477215,1.712079976,0.997022957,3.03218656,0.118459596,DB0088710003988_,2.133183342,0.537708992,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bumetanide,DB00887
,165038,DB01115,10003988,70,3530,25,2243,0.014179413,1.778986018,1.108608709,2.94139151,0.047072793,DB0111510003988_,3.056060095,0.576043549,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,nifedipine,DB01115
,165100,DB00047,10046306,35,9250,27,8491,0.526329923,1.189917347,0.699124228,2.046009896,0.684187125,DB0004710046306_,0.379523825,0.173883848,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,165102,DB00175,10046306,49,8082,28,6078,0.298730925,1.316046855,0.809841161,2.177412176,0.464720053,DB0017510046306_,0.766320092,0.274632436,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,pravastatin,DB00175
,165104,DB00343,10046306,68,8668,23,5072,0.02192957,1.729917124,1.062835025,2.912860759,0.066472785,DB0034310046306_,2.710962669,0.548073502,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,diltiazem,DB00343
,165106,DB00646,10046306,38,3415,20,1980,0.785321269,1.10160483,0.623077263,2.004041271,0.883559959,DB0064610046306_,0.123796124,0.096768053,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,nystatin,DB00646
,165109,DB00688,10046306,36,6454,22,5356,0.291130617,1.357937435,0.776437299,2.426278775,0.456517123,DB0068810046306_,0.78412907,0.305966957,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,165116,DB01015,10046306,89,9798,54,9327,0.009138432,1.568876595,1.105050101,2.245476087,0.033126975,DB0101510046306_,3.407407378,0.450359819,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,165128,DB00213,10046555,30,18865,53,13368,4.74589978436282e-05,0.4011116,0.247304137,0.639716483,0.000422581,DB0021310046555_,7.769128895,-0.913515586,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,165191,DB00512,10008479,37,4700,38,5060,0.907787485,1.048278852,0.647092764,1.696791309,0.958771936,DB0051210008479_,0.042102046,0.047149631,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,165195,DB00169,10017918,95,38596,30,18145,0.067534925,1.488724001,0.977964278,2.326515717,0.156912888,DB0016910017918_,1.852064484,0.397919378,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,165196,DB00213,10017918,44,18851,14,13407,0.007275644,2.235160295,1.201630617,4.418147839,0.027597993,DB0021310017918_,3.590012224,0.804312946,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,165200,DB00635,10017918,84,32969,24,23770,2.19727073848687e-05,2.523367282,1.586551312,4.156194391,0.000216515,DB0063510017918_,8.437852718,0.925594233,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,prednisone,DB00635
,165209,DB00653,10019211,37,1055,19,803,0.173744273,1.481918566,0.823469904,2.749904456,0.315838599,DB0065310019211_,1.152523959,0.393337576,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,magnesium sulfate,DB00653
,165212,DB14512,10006451,70,4774,16,2396,0.003711975,2.195543886,1.25885627,4.059431465,0.016057927,DB1451210006451_,4.131552685,0.7864298,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,mometasone furoate,DB14512
,165239,DB00363,10013642,25,4603,32,6856,0.589728919,1.163623037,0.660172871,2.029566262,0.736525141,DB0036310013642_,0.305811908,0.151538445,NA,10013642,Drooling,10029205,Nervous system disorders,Nerv,clozapine,DB00363
,165240,DB00363,10025482,45,4583,44,6844,0.050582523,1.527186273,0.983479996,2.373120945,0.126072599,DB0036310025482_,2.070897359,0.423427005,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,clozapine,DB00363
,165249,DB01611,10001760,246,11667,9,2352,7.27853955105388e-11,5.509880736,2.849775385,12.21109767,2.43405104452228e-09,DB0161110001760_,19.83370887,1.706542978,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxychloroquine,DB01611
,165250,DB00005,10027940,61,128021,36,42383,0.009218442,0.560975409,0.36558382,0.872140481,0.03335491,DB0000510027940_,3.400550278,-0.578078209,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,165272,DB01373,10029410,61,22659,23,7358,0.526997059,0.861262008,0.524899048,1.459180818,0.684700245,DB0137310029410_,0.378774135,-0.149356514,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,165285,DB01267,10039626,61,2791,108,3607,0.058903685,0.729983874,0.522224747,1.012580622,0.141402197,DB0126710039626_,1.956146992,-0.314732836,NA,10039626,Schizophrenia,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,165295,DB00514,10011224,47,2119,20,1516,0.059993973,1.681037348,0.972199338,3.008116746,0.143462663,DB0051410011224_,1.941680469,0.519411072,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dextromethorphan,DB00514
,165296,DB00868,10028810,68,2916,35,1611,0.835170319,1.073359327,0.700343793,1.671006846,0.914685493,DB0086810028810_,0.089174996,0.070793288,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,benzonatate,DB00868
,165305,DB00295,10054112,84,14579,49,9553,0.535194976,1.123320365,0.77975871,1.633668395,0.691758455,DB0029510054112_,0.368518438,0.116288911,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,morphine,DB00295
,165314,DB01104,10054236,56,15407,21,7265,0.394815737,1.257391816,0.748754867,2.188010099,0.564682319,DB0110410054236_,0.571491974,0.229039588,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,sertraline,DB01104
,165323,DB00571,10003988,75,5048,37,2572,0.920073705,1.032784811,0.685587997,1.580087631,0.964606718,DB0057110003988_,0.036034806,0.032258854,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,propranolol,DB00571
,165330,DB00571,10041349,80,5043,49,2560,0.30306423,0.828824536,0.571697723,1.212137468,0.469502167,DB0057110041349_,0.756082364,-0.187746803,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,propranolol,DB00571
,165331,DB00697,10041349,106,5990,27,1779,0.532812639,1.165956347,0.755326638,1.857559962,0.689628728,DB0069710041349_,0.371601902,0.153541649,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,165351,DB00331,10001052,16,24930,48,20704,1.8703326135764e-06,0.276835826,0.146688069,0.49633637,2.49741898642904e-05,DB0033110001052_,10.59766767,-1.284330635,male,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,165418,DB00268,10000059,41,2934,12,1533,0.081102991,1.784984782,0.917085026,3.742217635,0.180247917,DB0026810000059_,1.713422058,0.57940989,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ropinirole,DB00268
,165422,DB00268,10006451,44,2931,17,1528,0.342429399,1.349229191,0.752464655,2.52793978,0.511751556,DB0026810006451_,0.669916014,0.29953346,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,ropinirole,DB00268
,165425,DB00697,10011224,116,5980,24,1782,0.126957687,1.440218041,0.918569963,2.345795397,0.25140941,DB0069710011224_,1.380672555,0.364794519,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tizanidine,DB00697
,165445,DB00455,10068319,99,9302,26,5092,0.000478338,2.084271343,1.339887416,3.350254076,0.002978002,DB0045510068319_,5.816502601,0.734419318,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,165455,DB00218,10013709,48,1394,53,897,0.009143469,0.582923606,0.382419618,0.886602998,0.033138378,DB0021810013709_,3.407063207,-0.539699137,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,moxifloxacin,DB00218
,165458,DB00218,10059866,22,1420,32,918,0.00445878,0.444605433,0.244449747,0.794930631,0.018640004,DB0021810059866_,3.982445256,-0.810568057,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,moxifloxacin,DB00218
,165468,DB08932,10017533,70,19373,7,6590,0.000536178,3.401656274,1.565688757,8.774794275,0.003268804,DB0893210017533_,5.72333116,1.224262452,female,10017533,Fungal infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,165480,DB01016,10035664,28,1073,35,1193,0.702010578,0.889517935,0.517453196,1.516362722,0.821162745,DB0101610035664_,0.197033961,-0.11707561,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,glyburide,DB01016
,165482,DB08932,10061623,61,19382,28,6569,0.18095701,0.738376712,0.464331858,1.200950762,0.325072103,DB0893210061623_,1.123708265,-0.303301135,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,165496,DB14500,10005750,85,7724,32,4041,0.118086832,1.389645868,0.91368753,2.161087903,0.238313361,DB1450010005750_,1.434168828,0.329048944,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,potassium,DB14500
,165499,DB00476,10006093,35,17222,20,6157,0.093784933,0.625652753,0.3510159,1.144712727,0.201408306,DB0047610006093_,1.602421059,-0.468959769,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,duloxetine,DB00476
,165510,DB00465,10013968,61,2043,28,855,0.723668463,0.911769557,0.569344436,1.492603355,0.837567909,DB0046510013968_,0.177252933,-0.092367999,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ketorolac,DB00465
,165514,DB00476,10019196,64,17193,25,6152,0.718025648,0.916014621,0.568203645,1.519633556,0.833497656,DB0047610019196_,0.18212439,-0.087722953,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,165524,DB00465,10037844,55,2049,16,867,0.235715258,1.454383658,0.815767976,2.735116833,0.392871219,DB0046510037844_,0.934273407,0.374582208,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ketorolac,DB00465
,165525,DB00697,10037844,155,5941,45,1761,1,1.020987386,0.724931983,1.462824987,1,DB0069710037844_,0,0.020770184,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,tizanidine,DB00697
,165526,DB00295,10068319,47,14616,17,9585,0.039785151,1.813016315,1.021212134,3.370097877,0.105264754,DB0029510068319_,2.251276637,0.594991931,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,165528,DB00575,10068319,39,5205,16,3813,0.054877754,1.785511932,0.973356291,3.42784643,0.134113873,DB0057510068319_,2.009066041,0.579705171,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonidine,DB00575
,165530,DB14500,10068319,68,7741,15,4058,0.001563411,2.376323924,1.342449681,4.482134097,0.007953249,DB1450010068319_,4.834174793,0.865554724,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,165532,DB08932,10011703,39,19404,20,6577,0.134955441,0.660965724,0.375912383,1.197033863,0.262568746,DB0893210011703_,1.337242341,-0.414053295,NA,10011703,Cyanosis,10047065,Vascular disorders,Vasc,macitentan,DB08932
,165536,DB08932,10062244,128,19315,21,6576,0.00122081,2.07525067,1.300235947,3.470528602,0.006487209,DB0893210062244_,5.037922834,0.730081951,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,165585,DB08932,10016766,121,19322,34,6563,0.355395612,1.208792142,0.819384857,1.826457565,0.525132201,DB0893210016766_,0.644105237,0.189621631,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,165588,DB00698,10025482,86,3062,10,419,0.750683734,1.176737988,0.603711395,2.5614635,0.859058816,DB0069810025482_,0.151917889,0.162746194,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,nitrofurantoin,DB00698
,165601,DB08868,10053762,50,9152,15,2496,0.761796617,0.909084201,0.501300764,1.74619524,0.867975499,DB0886810053762_,0.141591791,-0.095317559,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,fingolimod,DB08868
,165611,DB00715,10024855,36,4807,16,2271,0.882830668,1.062971296,0.573637264,2.056183935,0.951043643,DB0071510024855_,0.050195326,0.061068096,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,paroxetine,DB00715
,165612,DB00829,10024855,57,7995,26,4428,0.490332855,1.214145503,0.749838457,2.014944199,0.653603078,DB0082910024855_,0.425255026,0.19404054,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,165684,DB00722,10000125,32,25371,24,26008,0.285069445,1.366795855,0.779885542,2.425747798,0.449660211,DB0072210000125_,0.799263067,0.312469208,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,165700,DB01097,10020751,122,6143,7,1496,8.23847369846037e-06,4.243899113,1.992730469,10.80461912,9.17966431386311e-05,DB0109710020751_,9.295934828,1.445482449,female,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,leflunomide,DB01097
,165701,DB01373,10020751,229,22491,50,7331,0.009563411,1.492808194,1.0938516,2.072580955,0.034361871,DB0137310020751_,3.370807738,0.40065904,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,calcium,DB01373
,165702,DB00999,10022061,157,21273,31,12208,2.67702145695794e-09,2.906302293,1.965936087,4.42484849,6.82828811219209e-08,DB0099910022061_,16.49960674,1.066881583,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,165704,DB00341,10033557,116,11289,27,5041,0.001855504,1.918405908,1.25132396,3.038735288,0.009150432,DB0034110033557_,4.693954201,0.651494585,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,cetirizine,DB00341
,165705,DB01097,10033775,63,6202,13,1490,0.770165966,1.164241994,0.632149938,2.31247184,0.874085165,DB0109710033775_,0.134577465,0.152070226,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,leflunomide,DB01097
,165706,DB01611,10041349,95,11818,20,2341,0.800967293,0.940909545,0.575095229,1.612841337,0.892358774,DB0161110041349_,0.113887015,-0.06090827,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,hydroxychloroquine,DB01611
,165722,DB06605,10051055,273,13800,278,12755,0.263051601,0.907655345,0.763883864,1.078456604,0.424868498,DB0660510051055_,0.855975575,-0.096890549,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,apixaban,DB06605
,165727,DB00544,10021015,36,2399,18,2635,0.005927021,2.196431255,1.211284149,4.120273401,0.023441432,DB0054410021015_,3.753250236,0.786833886,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,fluorouracil,DB00544
,165729,DB06637,10020100,42,6120,9,2010,0.327378066,1.532565785,0.733710054,3.587333548,0.495815878,DB0663710020100_,0.701550635,0.426943315,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,dalfampridine,DB06637
,165737,DB00722,10037876,35,25368,32,26000,0.714145716,1.120995843,0.673837692,1.870811177,0.830507805,DB0072210037876_,0.185717952,0.114217436,NA,10037876,Rash papular,10040785,Skin and subcutaneous tissue disorders,Skin,lisinopril,DB00722
,165742,DB00281,10067482,81,11377,26,5645,0.062993312,1.545744258,0.981755263,2.508819902,0.14894119,DB0028110067482_,1.904203751,0.435505514,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,165743,DB00316,10067482,136,65338,56,36897,0.050284999,1.371433583,0.997352664,1.907639488,0.125521481,DB0031610067482_,2.075278368,0.315856604,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,165749,DB00904,10067482,67,23002,24,14432,0.017456009,1.751531169,1.083648512,2.921578753,0.055535124,DB0090410067482_,2.890739598,0.560490359,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,165752,DB06637,10022095,45,6117,6,2013,0.033223376,2.468041745,1.047476181,7.089584066,0.091771711,DB0663710022095_,2.388451184,0.90342502,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,165753,DB06616,10000087,35,926,21,782,0.275238247,1.40721731,0.789191153,2.566661107,0.438529311,DB0661610000087_,0.824328625,0.341614216,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,bosutinib,DB06616
,165759,DB00028,10024855,41,13417,19,5596,0.673165231,0.900031624,0.510151862,1.643314268,0.80169218,DB0002810024855_,0.221030561,-0.105325378,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,165765,DB06605,10029148,33,14040,36,12997,0.54702309,0.84857598,0.512391358,1.401101591,0.701715523,DB0660510029148_,0.354227194,-0.164195652,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,apixaban,DB06605
,165769,DB06700,10074903,53,2172,14,604,1,1.052761465,0.571049997,2.069186393,1,DB0670010074903_,0,0.051416679,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,desvenlafaxine,DB06700
,165791,DB00559,10049438,54,9605,27,3279,0.123863146,0.682791489,0.421847227,1.129415755,0.24688097,DB0055910049438_,1.398848963,-0.381565752,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,165797,DB00514,10016173,49,2117,31,1505,0.647854535,1.123700772,0.698569715,1.832295177,0.782917966,DB0051410016173_,0.244727358,0.116627499,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,dextromethorphan,DB00514
,165802,DB00231,10010264,56,3240,23,2116,0.06382958,1.589994022,0.959270594,2.716140047,0.150370647,DB0023110010264_,1.89465205,0.463730256,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,165804,DB05351,10010264,56,2667,25,1106,0.805267142,0.928944145,0.566786431,1.562084694,0.894590507,DB0535110010264_,0.1113892,-0.073706666,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,dexlansoprazole,DB05351
,165805,DB00471,10010305,104,14085,35,5430,0.568651629,1.14552328,0.773136329,1.734097955,0.719678755,DB0047110010305_,0.32895034,0.135861545,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,montelukast,DB00471
,165810,DB01373,10020919,46,22674,13,7368,0.762636888,1.149828945,0.610409846,2.321209714,0.868521505,DB0137310020919_,0.140962932,0.139613188,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,calcium,DB01373
,165813,DB00203,10047340,41,13837,20,8918,0.358475918,1.321215422,0.755946926,2.381884031,0.528169626,DB0020310047340_,0.638337786,0.278552087,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,sildenafil,DB00203
,165816,DB00471,10047340,57,14132,7,5458,0.001832546,3.145000682,1.430358191,8.1761905,0.009055215,DB0047110047340_,4.70441446,1.145814107,female,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,montelukast,DB00471
,165821,DB00471,10048334,45,14144,12,5453,0.30110475,1.445675115,0.751449979,3.004907546,0.467361798,DB0047110048334_,0.760651594,0.36857642,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,165822,DB00656,10048334,34,11979,20,6599,0.886900203,0.936501321,0.52335468,1.718406405,0.95298528,DB0065610048334_,0.048155821,-0.065604346,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,165825,DB08932,10048334,62,19381,14,6583,0.18736534,1.504156451,0.832057698,2.911663792,0.333224937,DB0893210048334_,1.09893753,0.408232243,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,165833,DB00335,10040984,41,8425,18,5447,0.18340541,1.47260788,0.826315387,2.726249129,0.328147246,DB0033510040984_,1.114292851,0.387034897,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,atenolol,DB00335
,165835,DB01164,10064685,36,6488,46,7890,0.911487701,0.951717145,0.596949531,1.506718088,0.96027793,DB0116410064685_,0.040532526,-0.049487405,NA,10064685,Device occlusion,10077536,Product issues,Prod,calcium chloride,DB01164
,165836,DB01164,10035598,38,6486,35,7901,0.240355476,1.322540879,0.812318735,2.158896493,0.398231503,DB0116410035598_,0.920721776,0.279554794,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium chloride,DB01164
,165840,DB00246,10028813,50,1024,13,688,0.001518871,2.582910874,1.369548799,5.223538263,0.007773273,DB0024610028813_,4.857063931,0.948917009,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ziprasidone,DB00246
,165884,DB00175,10031161,53,8078,6,6100,7.9885712897405e-08,6.669464736,2.86689182,18.9977675,1.4750937572942e-06,DB0017510031161_,13.42678901,1.897539607,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,165885,DB00213,10031161,78,18817,14,13407,9.74929432401442e-08,3.969444669,2.228807602,7.598153839,1.76548536897499e-06,DB0021310031161_,13.24708491,1.378626203,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,165908,DB00996,10061159,36,38917,16,22409,0.471716281,1.29558867,0.700678639,2.501026816,0.637844665,DB0099610061159_,0.449660497,0.258965163,NA,10061159,Foot deformity,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,165913,DB00316,10011953,31,65443,20,36933,0.662964524,0.874753968,0.482879134,1.619490307,0.794529694,DB0031610011953_,0.23000492,-0.133812611,NA,10011953,Decreased activity,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,165924,DB00316,10022093,196,65278,25,36928,1.06134812810242e-16,4.434861662,2.915894535,7.023892465,7.90298457426975e-15,DB0031610022093_,32.47153591,1.489496423,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,165926,DB00316,10022095,193,65281,40,36913,2.84708339052483e-10,2.728252853,1.932213401,3.93855998,8.66152626388254e-09,DB0031610022095_,18.56437489,1.003661424,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,165928,DB00316,10022107,77,65397,9,36944,1.06194056712767e-07,4.832616425,2.417595631,10.97014033,1.91645093078961e-06,DB0031610022107_,13.16503556,1.575388024,female,10022107,Injection site urticaria,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,165930,DB01050,10022107,44,18064,8,9363,0.003246506,2.850688092,1.326706693,7.013353395,0.014425798,DB0105010022107_,4.238737172,1.047560401,female,10022107,Injection site urticaria,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,165940,DB00555,10014380,43,7004,31,3455,0.108539709,0.68424786,0.420436296,1.12545806,0.223833286,DB0055510014380_,1.496853763,-0.379435059,NA,10014380,Electrocardiogram QRS complex prolonged,10022891,Investigations,Inv,lamotrigine,DB00555
,165945,DB06605,10023547,51,14022,44,12989,0.758414829,1.073727131,0.702697651,1.646443545,0.865137628,DB0660510023547_,0.144866677,0.071135896,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,apixaban,DB06605
,165954,DB00007,10003239,82,1865,95,4357,6.55260645577766e-06,2.016323458,1.474277145,2.752576822,7.49174687647306e-05,DB0000710003239_,9.499123467,0.701275783,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,leuprolide,DB00007
,165958,DB00433,10028836,50,7606,8,6012,1.5931870731544e-06,4.939690832,2.321247313,12.07450678,2.17316669527054e-05,DB0043310028836_,10.73674005,1.597302745,female,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,prochlorperazine,DB00433
,165976,DB08868,10018823,55,9147,8,2503,0.121784097,1.881156334,0.889360272,4.579810128,0.243948711,DB0886810018823_,1.410797279,0.631886659,NA,10018823,Haemangioma of skin,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fingolimod,DB08868
,165978,DB08868,10028245,156,9046,44,2467,0.862001125,0.966906779,0.685763943,1.388010636,0.935727247,DB0886810028245_,0.066431247,-0.03365319,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,165992,DB00722,10046543,45,25358,33,25999,0.173491698,1.398090801,0.872186246,2.262381938,0.315499465,DB0072210046543_,1.153598291,0.335107592,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,165993,DB01373,10046543,70,22650,18,7363,0.456390923,1.264171478,0.744109883,2.257143542,0.623764321,DB0137310046543_,0.471982673,0.23441695,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,calcium,DB01373
,165998,DB01104,10005191,47,15416,17,7269,0.42108668,1.303558994,0.734162204,2.423409881,0.590118542,DB0110410005191_,0.527431844,0.265098212,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,sertraline,DB01104
,166000,DB13961,10005191,38,9419,22,6392,0.599829398,1.172132046,0.675095811,2.082796502,0.744405842,DB1396110005191_,0.295168906,0.158824352,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,fish oil,DB13961
,166003,DB00682,10012218,22,19437,31,16333,0.07233587,0.596361395,0.328843934,1.064170237,0.165349017,DB0068210012218_,1.799696783,-0.516908429,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,166015,DB00635,10014387,32,33021,33,23761,0.166318365,0.697783599,0.415286289,1.171083356,0.305907665,DB0063510014387_,1.184471972,-0.359846254,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,prednisone,DB00635
,166020,DB00153,10017955,45,7378,28,3411,0.255359519,0.743013945,0.452664223,1.239168825,0.416091965,DB0015310017955_,0.876848974,-0.297040466,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,166030,DB00682,10040893,41,19418,32,16332,0.814439089,1.077650122,0.661874547,1.76876398,0.900478746,DB0068210040893_,0.104828717,0.074782857,NA,10040893,Skin necrosis,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,166050,DB00635,10051714,47,33006,20,23774,0.047856531,1.69266937,0.983351169,3.016691358,0.121080847,DB0063510051714_,2.1112968,0.526306792,NA,10051714,Calciphylaxis,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,166078,DB01175,10047340,48,10676,8,4884,0.00554958,2.744705746,1.285811923,6.723354374,0.022236388,DB0117510047340_,3.806025222,1.009673873,female,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,escitalopram,DB01175
,166086,DB00254,10009033,38,5897,29,3359,0.252054325,0.746432508,0.447390719,1.257401866,0.412167611,DB0025410009033_,0.886325189,-0.292450077,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxycycline,DB00254
,166095,DB14500,10037400,51,7758,27,4046,1,0.985099651,0.605226645,1.636503885,1,DB1450010037400_,0,-0.015012474,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,166096,DB01590,10031009,91,4647,66,2801,0.279388195,0.83109882,0.596528606,1.163132437,0.443207019,DB0159010031009_,0.813718307,-0.185006574,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,everolimus,DB01590
,166103,DB00231,10040047,40,3256,32,2107,0.396309112,0.808931429,0.493754053,1.33499145,0.565971004,DB0023110040047_,0.569212431,-0.212041126,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,temazepam,DB00231
,166111,DB01202,10057668,46,6668,67,5651,0.005729954,0.581884988,0.390177344,0.861135172,0.022820423,DB0120210057668_,3.780099412,-0.541482467,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,166128,DB00572,10013700,107,2795,26,2100,3.24730937576225e-08,3.091380919,1.990130456,4.96484659,6.51817693332652e-07,DB0057210013700_,14.24350093,1.128617891,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,atropine,DB00572
,166163,DB00588,10042458,95,16429,35,8433,0.095218426,1.3932244,0.935553975,2.117759223,0.203547196,DB0058810042458_,1.591857382,0.331620773,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,166165,DB00363,10003549,24,4604,30,6858,0.578422127,1.191634203,0.665778155,2.111436044,0.727177426,DB0036310003549_,0.31858478,0.175325645,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,clozapine,DB00363
,166180,DB00028,10000059,64,13394,28,5587,0.819340156,0.953433409,0.601896925,1.545963552,0.903692843,DB0002810000059_,0.101265751,-0.047685695,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,human immunoglobulin g,DB00028
,166191,DB01015,10001052,32,9855,41,9340,0.240601032,0.739716178,0.450478826,1.204900652,0.398575541,DB0101510001052_,0.919858235,-0.301488709,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,166218,DB00158,10033318,48,16767,21,8083,0.797361033,1.101885007,0.646744844,1.938809312,0.890416974,DB0015810033318_,0.116065415,0.097022356,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,folic acid,DB00158
,166227,DB00158,10040070,45,16770,40,8064,0.005241007,0.540954534,0.345140287,0.85065537,0.021246124,DB0015810040070_,3.851580804,-0.614420045,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,folic acid,DB00158
,166230,DB00351,10047700,40,626,38,826,0.161278632,1.388614828,0.856962078,2.253479169,0.299199551,DB0035110047700_,1.206644532,0.328306724,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,megestrol acetate,DB00351
,166277,DB00136,10010774,34,2058,31,1651,0.61692993,0.879902138,0.522316506,1.48729243,0.758040539,DB0013610010774_,0.277018414,-0.127944585,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,calcitriol,DB00136
,166314,DB01409,10033775,49,5982,20,3946,0.083210175,1.616056814,0.941348118,2.874796126,0.183804315,DB0140910033775_,1.693883595,0.479989117,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,tiotropium,DB01409
,166315,DB13867,10033775,46,4504,16,2538,0.110444883,1.619957721,0.897972087,3.072134219,0.226738295,DB1386710033775_,1.483958813,0.48240005,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,fluticasone,DB13867
,166317,DB00512,10014625,62,4675,68,5030,0.929819089,0.98099994,0.682268874,1.408282818,0.971182561,DB0051210014625_,0.029240814,-0.01918288,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,vancomycin,DB00512
,166318,DB00581,10014625,27,2086,32,2037,0.512905523,0.823969941,0.47308247,1.425335435,0.673016298,DB0058110014625_,0.395985733,-0.193621229,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,lactulose,DB00581
,166323,DB01060,10037884,43,8544,24,5057,0.899415404,1.060447976,0.628387685,1.829210364,0.956490275,DB0106010037884_,0.044484657,0.058691437,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,amoxicillin,DB01060
,166326,DB00641,10040984,46,14078,32,12443,0.30890218,1.270537583,0.791266909,2.062957618,0.476230611,DB0064110040984_,0.741853064,0.239440104,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,166327,DB00678,10040984,44,15555,34,10690,0.644942255,0.889373665,0.55520195,1.43585637,0.780773851,DB0067810040984_,0.247469735,-0.117237811,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,losartan,DB00678
,166328,DB00706,10040984,6,1069,48,15877,0.153506772,1.856343763,0.647752312,4.357708362,0.28887324,DB0070610040984_,1.241767302,0.618608834,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,tamsulosin,DB00706
,166338,DB00959,10043528,43,8035,19,4983,0.2400909,1.403489001,0.79952026,2.553212637,0.397949376,DB0095910043528_,0.921430478,0.33896128,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,166358,DB01097,10060933,45,6220,8,1495,0.599760955,1.351936633,0.62897303,3.328012713,0.744338474,DB0109710060933_,0.295259409,0.301538108,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,166360,DB06605,10009802,33,14040,22,13011,0.279838077,1.390043366,0.785992373,2.50389365,0.443678105,DB0660510009802_,0.812655968,0.329334945,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,apixaban,DB06605
,166372,DB00203,10067482,28,13850,32,8906,0.033185982,0.562687388,0.326145164,0.965447751,0.091694895,DB0020310067482_,2.389288572,-0.575031067,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,166373,DB00331,10067482,138,24808,80,20672,0.009551529,1.43739317,1.082829627,1.918838261,0.034333156,DB0033110067482_,3.371643755,0.362831175,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,166374,DB00341,10067482,55,11350,24,5044,1,1.018437517,0.619126339,1.722501066,1,DB0034110067482_,0,0.018269606,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,166375,DB00996,10067482,97,38856,54,22371,0.866089022,1.034202964,0.733665083,1.471227613,0.939291974,DB0099610067482_,0.062628907,0.033631047,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,166379,DB08906,10003549,63,2130,40,1118,0.346053624,0.826750439,0.543644914,1.270055658,0.515472034,DB0890610003549_,0.662672227,-0.190252396,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,fluticasone furoate,DB08906
,166398,DB00715,10000059,51,4792,18,2269,0.303220123,1.341564492,0.768470927,2.445810767,0.46968831,DB0071510000059_,0.755685975,0.293836464,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,paroxetine,DB00715
,166400,DB00983,10000087,38,3463,13,1727,0.295795407,1.457642254,0.757123507,2.990319453,0.461615049,DB0098310000087_,0.773023963,0.376820236,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,formoterol,DB00983
,166403,DB00264,10002368,20,29587,33,24859,0.018429314,0.509224482,0.27681186,0.914345045,0.0579206,DB0026410002368_,2.848682178,-0.674866334,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,166405,DB00338,10002368,42,33632,35,22237,0.351462027,0.793434947,0.494376623,1.280508646,0.521161276,DB0033810002368_,0.651695735,-0.231383725,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,166412,DB00169,10010144,52,38639,28,18147,0.55056054,0.872226676,0.540582553,1.434771448,0.704654224,DB0016910010144_,0.350048059,-0.136705939,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,166413,DB00175,10010144,61,8070,30,6076,0.056361906,1.530874917,0.972094919,2.458733884,0.136749221,DB0017510010144_,1.989606532,0.425839413,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,pravastatin,DB00175
,166414,DB00264,10010144,1011,28596,640,24252,1.01368542016948e-08,1.339708554,1.210403987,1.483654991,2.28025000163926e-07,DB0026410010144_,15.29381056,0.292452093,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,166415,DB00295,10010144,459,14204,254,9348,0.029481763,1.189253311,1.015707167,1.394942925,0.083571759,DB0029510010144_,2.482049632,0.17332564,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,morphine,DB00295
,166416,DB00338,10010144,254,33420,232,22040,0.000396151,0.722041762,0.601411619,0.867160148,0.002541574,DB0033810010144_,5.974971521,-0.3256723,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,166417,DB00421,10010144,60,8843,30,5222,0.511959291,1.181069858,0.748772274,1.899158597,0.672237485,DB0042110010144_,0.397143601,0.166420687,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,spironolactone,DB00421
,166418,DB00661,10010144,489,3039,321,1274,2.20941129632376e-08,0.638670166,0.545336762,0.748578502,4.58904590469142e-07,DB0066110010144_,14.59442351,-0.44836713,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,verapamil,DB00661
,166419,DB00715,10010144,288,4555,146,2141,0.490349345,0.927199874,0.751948506,1.147091744,0.653608486,DB0071510010144_,0.425246752,-0.075586122,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,paroxetine,DB00715
,166420,DB00761,10010144,122,15185,112,8513,0.000208232,0.61065856,0.467926874,0.797596854,0.001489963,DB0076110010144_,6.509004056,-0.493217298,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,potassium chloride,DB00761
,166423,DB00175,10013786,39,8092,17,6089,0.059284955,1.726188152,0.952809964,3.257564857,0.142142208,DB0017510013786_,1.950927255,0.545915597,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,pravastatin,DB00175
,166429,DB00338,10022998,105,33569,69,22203,1,1.006499256,0.735464624,1.384929494,1,DB0033810022998_,0,0.006478227,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,166434,DB00175,10028836,51,8080,20,6086,0.011587564,1.920609119,1.123702699,3.40484978,0.040054458,DB0017510028836_,3.217515308,0.652642385,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,166437,DB00661,10037087,55,3473,13,1582,0.034269521,1.926960073,1.035613524,3.85655845,0.093933402,DB0066110037087_,2.365169238,0.655943669,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,verapamil,DB00661
,166439,DB00338,10040844,113,33561,70,22202,0.705596081,1.067925713,0.785280273,1.460912667,0.823597413,DB0033810040844_,0.194073445,0.065718181,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,166446,DB00722,10018358,29,25374,30,26002,1,0.990590965,0.573497753,1.708677273,1,DB0072210018358_,0,-0.00945358,NA,10018358,Glomerular filtration rate decreased,10022891,Investigations,Inv,lisinopril,DB00722
,166447,DB00363,10013573,44,4584,55,6833,0.410710474,1.192470224,0.782063899,1.808912291,0.580096036,DB0036310013573_,0.54456161,0.176026974,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,clozapine,DB00363
,166449,DB00531,10016322,45,7207,25,6491,0.055018587,1.621112491,0.971807046,2.761967069,0.134364355,DB0053110016322_,2.007200105,0.483112637,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,166466,DB00181,10053762,246,9610,170,5701,0.136344345,0.858461459,0.701146331,1.053011305,0.264577352,DB0018110053762_,1.329621622,-0.152613493,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,166477,DB00678,10012671,26,15573,33,10691,0.023325852,0.540913066,0.310460404,0.933091088,0.069636386,DB0067810012671_,2.664468056,-0.614496704,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,166479,DB01076,10012671,61,25686,73,25510,0.299834459,0.829895056,0.580549617,1.18276203,0.465871535,DB0107610012671_,0.763845359,-0.186456025,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,166481,DB08917,10028813,126,790,16,178,0.043516565,1.773641495,1.018780424,3.279595343,0.112665147,DB0891710028813_,2.183335164,0.573034775,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ferric carboxymaltose,DB08917
,166537,DB08895,10040882,82,28032,27,6619,0.142647865,0.717122536,0.458810645,1.15369157,0.273516367,DB0889510040882_,1.296393815,-0.332508551,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,166538,DB01060,10015150,71,8516,37,5044,0.550512502,1.13658277,0.752231488,1.742750845,0.704654224,DB0106010015150_,0.350048059,0.12802619,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,amoxicillin,DB01060
,166553,DB01050,10033645,32,18076,30,9341,0.022032061,0.551201098,0.324184692,0.939662362,0.066706528,DB0105010033645_,2.707452454,-0.595655568,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,166557,DB08868,10048959,80,9122,8,2503,0.003723234,2.743801666,1.325001206,6.583285839,0.016093605,DB0886810048959_,4.129333286,1.009344428,female,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,166561,DB01039,10012174,34,2939,33,3018,0.902343547,1.058012323,0.633930244,1.767530839,0.957195726,DB0103910012174_,0.043747388,0.056391981,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,fenofibrate,DB01039
,166590,DB00635,10052428,64,32989,26,23768,0.013589304,1.773471965,1.107846482,2.916249793,0.04545516,DB0063510052428_,3.091028924,0.572939188,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,166630,DB01216,10003553,6,230,47,7068,0.006677431,3.92176067,1.356231162,9.317415249,0.025805526,DB0121610003553_,3.657166627,1.366540703,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,finasteride,DB01216
,166636,DB01216,10037844,7,229,163,6952,0.503478146,1.303666406,0.510134357,2.791799471,0.664620483,DB0121610037844_,0.408539103,0.265180607,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,finasteride,DB01216
,166660,DB00196,10070863,25,5058,31,3254,0.018747049,0.518850986,0.29314695,0.90984259,0.058722062,DB0019610070863_,2.834939781,-0.656138555,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,fluconazole,DB00196
,166665,DB00341,10008190,67,11338,49,5019,0.008584038,0.605304419,0.411912494,0.895077088,0.03151057,DB0034110008190_,3.457432224,-0.502023776,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,166687,DB00490,10024855,34,4036,17,1559,0.43267556,0.772572306,0.418392203,1.479161219,0.601087556,DB0049010024855_,0.509014671,-0.258029675,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,buspirone,DB00490
,166690,DB01241,10033425,33,910,22,1049,0.054783497,1.728631731,0.970059623,3.136624984,0.133976947,DB0124110033425_,2.010087529,0.547330189,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,gemfibrozil,DB01241
,166763,DB00047,10037377,36,9249,45,8473,0.181328898,0.732896039,0.458860472,1.163010115,0.325539927,DB0004710037377_,1.122270161,-0.310751417,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,166781,DB00820,10062352,46,11869,13,5803,0.094727741,1.729978867,0.918110132,3.493238774,0.202857399,DB0082010062352_,1.595252017,0.548109193,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,tadalafil,DB00820
,166784,DB00169,10053156,85,38606,18,18157,0.001377038,2.220907272,1.323886013,3.926872428,0.007166704,DB0016910053156_,4.938309357,0.797915793,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,166820,DB06643,10061257,161,52260,22,7493,0.911234815,1.049279254,0.669176615,1.722415036,0.960120631,DB0664310061257_,0.040696345,0.048103504,NA,10061257,Jaw disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,166824,DB00175,10000060,66,8065,29,6077,0.016378651,1.714799419,1.090866435,2.756534107,0.052768626,DB0017510000060_,2.941838476,0.539296117,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,pravastatin,DB00175
,166827,DB01065,10000060,31,4300,24,3027,0.783861031,0.909286031,0.515366253,1.622598701,0.882368791,DB0106510000060_,0.12514518,-0.095095568,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,melatonin,DB01065
,166828,DB00203,10007739,40,13838,26,8912,1,0.990804373,0.589457215,1.692220728,1,DB0020310007739_,0,-0.009238168,NA,10007739,Cataract,10015919,Eye disorders,Eye,sildenafil,DB00203
,166833,DB01050,10007739,57,18051,11,9360,0.001253667,2.686847941,1.393687561,5.68481415,0.006625645,DB0105010007739_,5.016807502,0.988368737,NA,10007739,Cataract,10015919,Eye disorders,Eye,ibuprofen,DB01050
,166840,DB00996,10013774,92,38861,17,22408,1.95737731546154e-06,3.12047086,1.846268728,5.587951407,2.59782545803544e-05,DB0099610013774_,10.55825073,1.137983907,female,10013774,Dry eye,10015919,Eye disorders,Eye,gabapentin,DB00996
,166846,DB00316,10015929,70,65404,20,36933,0.005828115,1.976401868,1.188097486,3.43123501,0.023130306,DB0031610015929_,3.766611592,0.681277953,NA,10015929,Eye infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,166847,DB00338,10015929,42,33632,16,22256,0.060687503,1.737076235,0.95606749,3.310604169,0.144667032,DB0033810015929_,1.93332051,0.552203375,NA,10015929,Eye infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,166862,DB00169,10017533,125,38566,30,18145,0.000530896,1.960363251,1.306846431,3.027212755,0.003239983,DB0016910017533_,5.732187312,0.673129788,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,166865,DB00338,10017533,90,33584,25,22247,5.18092546652532e-05,2.384697033,1.516269603,3.879274851,0.000455225,DB0033810017533_,7.694718263,0.869072086,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,166895,DB00175,10021789,66,8065,40,6066,0.324705587,1.241009961,0.824280575,1.889466602,0.49316074,DB0017510021789_,0.706920113,0.215925533,NA,10021789,Infection,10021881,Infections and infestations,Infec,pravastatin,DB00175
,166898,DB01065,10021789,37,4294,30,3021,0.618573411,0.867718548,0.520336345,1.457823976,0.759438666,DB0106510021789_,0.275175716,-0.14188787,NA,10021789,Infection,10021881,Infections and infestations,Infec,melatonin,DB01065
,166899,DB14513,10021789,71,7106,36,3528,0.918057751,0.979160683,0.645420139,1.50889439,0.963665508,DB1451310021789_,0.037011028,-0.02105952,NA,10021789,Infection,10021881,Infections and infestations,Infec,magnesium,DB14513
,166917,DB00433,10028810,84,7572,35,5985,0.001131388,1.89688643,1.262512928,2.904559063,0.006099342,DB0043310028810_,5.099574435,0.640213821,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,166919,DB00557,10028810,57,5930,13,3054,0.007255946,2.257939954,1.218819699,4.503542994,0.027537185,DB0055710028810_,3.59221802,0.814452873,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,hydroxyzine,DB00557
,166921,DB00829,10028810,93,7959,23,4431,0.000276911,2.25098959,1.411436508,3.729838563,0.001890989,DB0082910028810_,6.270655431,0.811369937,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,diazepam,DB00829
,166922,DB01065,10028810,79,4252,33,3018,0.011623027,1.699059103,1.115107321,2.641206702,0.04014339,DB0106510028810_,3.215297486,0.530074629,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,melatonin,DB01065
,166943,DB00557,10046306,46,5941,20,3047,0.602772363,1.179577022,0.682544217,2.109203961,0.746568874,DB0055710046306_,0.292267404,0.165155918,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,hydroxyzine,DB00557
,166948,DB00421,10058080,31,8872,36,5216,0.007262061,0.5062752,0.302468045,0.843003012,0.027554426,DB0042110058080_,3.591592103,-0.680674885,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,spironolactone,DB00421
,166952,DB00588,10058080,66,16458,31,8437,0.747706134,1.091416718,0.701472429,1.732093471,0.856639674,DB0058810058080_,0.154737899,0.087476594,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,167021,DB00641,10001497,39,14085,47,12428,0.160112099,0.73218196,0.465979386,1.144632747,0.297622923,DB0064110001497_,1.211927951,-0.311726217,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,167099,DB00563,10020635,52,46594,41,15307,5.31794814497863e-05,0.41666293,0.271267798,0.643805706,0.000465475,DB0056310020635_,7.672451278,-0.875477706,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,167125,DB00181,10008469,56,9800,12,5859,0.000591515,2.789833857,1.476578342,5.722338614,0.003553013,DB0018110008469_,5.639959367,1.025982044,female,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,167131,DB00181,10037844,170,9686,87,5784,0.269031285,1.166869388,0.893990885,1.531975061,0.431564078,DB0018110037844_,0.84033928,0.154324426,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,baclofen,DB00181
,167183,DB00399,10049848,46,6946,34,4964,0.909671852,0.966872967,0.606258,1.555725407,0.959437782,DB0039910049848_,0.04140781,-0.033688161,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,zoledronic acid,DB00399
,167207,DB00695,10039020,34,28015,56,20472,0.000158936,0.443674298,0.280793232,0.691731116,0.001185577,DB0069510039020_,6.737526096,-0.812664549,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,167211,DB00338,10048010,93,33581,29,22243,0.000270135,2.124112647,1.38632618,3.344606629,0.001851981,DB0033810048010_,6.291499608,0.753354137,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,167212,DB00497,10048010,75,19192,65,16310,0.932406466,0.980573212,0.693540101,1.389570699,0.973171181,DB0049710048010_,0.027195281,-0.019617968,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,167213,DB00695,10048010,46,28003,10,20518,0.000191737,3.370336474,1.677227012,7.493787239,0.001389908,DB0069510048010_,6.578517858,1.215012583,female,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,167241,DB00950,10022086,50,4668,13,2043,0.099373084,1.683194735,0.898369925,3.385445208,0.209918951,DB0095010022086_,1.561033772,0.520693615,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,167307,DB00471,10001949,62,14127,12,5453,0.026561829,1.994280255,1.063315669,4.069629777,0.076997813,DB0047110001949_,2.563978263,0.690283211,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,167308,DB00761,10001949,65,15242,24,8601,0.077352193,1.528276005,0.942976541,2.554757435,0.173852278,DB0076110001949_,1.749549315,0.424140306,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,167318,DB00121,10021097,55,4168,9,459,0.289197382,0.673054813,0.327191214,1.559537607,0.454298712,DB0012110021097_,0.789000342,-0.395928506,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,biotin,DB00121
,167324,DB00695,10034568,34,28015,20,20508,0.492047648,1.244455797,0.695861856,2.282322138,0.65501299,DB0069510034568_,0.423100211,0.218698324,NA,10034568,Peripheral coldness,10047065,Vascular disorders,Vasc,furosemide,DB00695
,167326,DB00996,10034568,37,38916,26,22399,0.434927698,0.819097715,0.482657851,1.409223137,0.603339379,DB0099610034568_,0.505275424,-0.199551893,NA,10034568,Peripheral coldness,10047065,Vascular disorders,Vasc,gabapentin,DB00996
,167332,DB00321,10042674,50,7397,12,2838,0.156147068,1.598613136,0.837885229,3.302843944,0.292313207,DB0032110042674_,1.229929424,0.469136463,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,167336,DB00115,10053156,39,18386,12,10460,0.059398822,1.848924065,0.947922737,3.880678354,0.142369765,DB0011510053156_,1.949327625,0.614603883,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,167339,DB00381,10053156,52,29308,19,22868,0.003837557,2.135404434,1.241029124,3.826008023,0.016495534,DB0038110053156_,4.104665584,0.758656059,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,167345,DB00115,10061224,60,18365,30,10442,0.660618857,1.137178479,0.72149348,1.827384333,0.792837988,DB0011510061224_,0.232136381,0.128550176,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,167347,DB00761,10061224,39,15268,14,8611,0.15449794,1.571087038,0.833911009,3.134477888,0.290100965,DB0076110061224_,1.237526263,0.451767761,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,167348,DB01050,10061224,46,18062,21,9350,0.699741878,1.133911506,0.662682211,2.00158156,0.81955344,DB0105010061224_,0.198995673,0.125673166,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,167351,DB00115,10061623,140,18285,106,10366,0.02779898,0.748781048,0.576933852,0.974174374,0.079783392,DB0011510061623_,2.528439917,-0.289308664,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,167354,DB00695,10061623,168,27881,114,20414,0.546026859,1.079022521,0.844961632,1.382007405,0.700725054,DB0069510061623_,0.355639689,0.076055558,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,167355,DB00761,10061623,91,15216,55,8570,0.666748834,0.9318816,0.658842248,1.328645642,0.797410733,DB0076110061623_,0.226385384,-0.070549511,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,167357,DB00863,10021015,54,10619,26,5814,0.640406061,1.137114851,0.698973779,1.893833356,0.777383487,DB0086310021015_,0.251821503,0.128494222,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,ranitidine,DB00863
,167362,DB00669,10028411,56,6321,11,1086,0.727777868,0.874700131,0.451581033,1.857627315,0.841122159,DB0066910028411_,0.173018376,-0.133874159,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sumatriptan,DB00669
,167366,DB10708,10016173,44,976,19,436,1,1.034462818,0.583572662,1.89929845,1,DB1070810016173_,0,0.033882275,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,flax seed,DB10708
,167368,DB00115,10019196,58,18367,41,10431,0.295698345,0.803419134,0.528996221,1.230244736,0.461518377,DB0011510019196_,0.773233406,-0.218878741,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,167409,DB00363,10046571,39,4589,44,6844,0.217299281,1.321863601,0.835015277,2.085604209,0.370253239,DB0036310046571_,0.993568077,0.27904256,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,clozapine,DB00363
,167410,DB00924,10015090,45,10117,24,4227,0.354603324,0.783386638,0.46657121,1.346227395,0.524447791,DB0092410015090_,0.645409396,-0.244128914,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,167417,DB00381,10029366,61,29299,45,22842,0.844795367,1.056824377,0.706979026,1.59025916,0.921636384,DB0038110029366_,0.081604511,0.055268541,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,amlodipine,DB00381
,167422,DB01050,10035598,51,18057,33,9338,0.35634702,0.79924112,0.505517821,1.279349536,0.526020353,DB0105010035598_,0.642415374,-0.224092602,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,167430,DB00924,10047942,97,10065,35,4216,0.502518876,1.160870045,0.779871977,1.764127982,0.663704176,DB0092410047942_,0.409918746,0.149169763,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,cyclobenzaprine,DB00924
,167431,DB00956,10047942,51,5763,29,3438,0.90781528,1.049128888,0.651071556,1.720206004,0.958771936,DB0095610047942_,0.042102046,0.047960189,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,hydrocodone,DB00956
,167436,DB00448,10061818,43,5102,26,3098,1,1.004236171,0.601863283,1.706190244,1,DB0044810061818_,0,0.004227224,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,167437,DB00924,10061818,58,10104,27,4224,0.634663445,0.898051034,0.558754787,1.477167033,0.772844497,DB0092410061818_,0.257677419,-0.107528382,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,167438,DB01190,10061818,34,4900,26,2259,0.068771211,0.602913022,0.350303023,1.048999488,0.159096223,DB0119010061818_,1.838246084,-0.505982335,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,clindamycin,DB01190
,167449,DB00230,10019303,72,19602,28,8623,0.663735417,1.131172635,0.721197061,1.819789395,0.795199773,DB0023010019303_,0.229161909,0.123254825,NA,10019303,Heart rate increased,10022891,Investigations,Inv,pregabalin,DB00230
,167450,DB00678,10019303,113,15486,52,10672,0.016899299,1.497527782,1.068059821,2.12380697,0.054153986,DB0067810019303_,2.915923705,0.403815603,NA,10019303,Heart rate increased,10022891,Investigations,Inv,losartan,DB00678
,167451,DB00230,10019974,103,19571,29,8622,0.036682339,1.564688789,1.026817812,2.453275493,0.098944681,DB0023010019974_,2.31319436,0.447686947,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,pregabalin,DB00230
,167452,DB00678,10019974,71,15528,35,10689,0.113350747,1.396388416,0.918277867,2.158984291,0.231124381,DB0067810019974_,1.464799268,0.3338892,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,losartan,DB00678
,167456,DB00230,10040831,45,19629,15,8636,0.401552246,1.319828741,0.7216602,2.55072266,0.571317264,DB0023010040831_,0.559810594,0.277501986,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,167471,DB11089,10049848,92,10083,46,8361,0.004586865,1.658387256,1.150365274,2.420045406,0.019063285,DB1108910049848_,3.959991038,0.505845598,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,docusate,DB11089
,167494,DB00203,10046735,64,13814,36,8902,0.539587212,1.145660128,0.749334502,1.776115031,0.6953498,DB0020310046735_,0.363340251,0.135981002,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,sildenafil,DB00203
,167534,DB00588,10019974,87,16437,22,8446,0.002202626,2.031955143,1.260081171,3.410267578,0.010523679,DB0058810019974_,4.554127451,0.708998454,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,167536,DB01097,10019974,52,6213,8,1495,0.323443177,1.563967595,0.735722022,3.821205352,0.491879784,DB0109710019974_,0.709520935,0.447225923,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,leflunomide,DB01097
,167545,DB00588,10042209,86,16438,18,8450,0.000240803,2.45595463,1.464320663,4.341851014,0.001681366,DB0058810042209_,6.388148613,0.898515537,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,167550,DB01097,10060795,75,6190,12,1491,0.219602574,1.505370927,0.810348685,3.050896443,0.372972041,DB0109710060795_,0.986251819,0.409039331,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,leflunomide,DB01097
,167573,DB08880,10005750,45,3293,10,799,1,1.091827236,0.539494822,2.440580761,1,DB0888010005750_,0,0.087852656,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,teriflunomide,DB08880
,167590,DB00333,10037660,41,3030,42,3110,1,1.001964199,0.633455508,1.58379215,1,DB0033310037660_,0,0.001962272,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,methadone,DB00333
,167599,DB00619,10025482,77,2822,58,2436,0.484565244,1.145966491,0.800758034,1.64762644,0.648694768,DB0061910025482_,0.432792984,0.136248378,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,167614,DB00213,10040829,96,18799,37,13384,0.001409063,1.847188016,1.251073576,2.779207391,0.007297256,DB0021310040829_,4.920256834,0.613664491,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,167723,DB00099,10035226,34,2351,31,1924,0.707110598,0.897595999,0.533137353,1.516247927,0.82485253,DB0009910035226_,0.19255066,-0.108035202,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,filgrastim,DB00099
,167727,DB00250,10035664,39,787,52,758,0.160496963,0.722510467,0.458616007,1.130235849,0.298159776,DB0025010035664_,1.210125775,-0.325023372,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,dapsone,DB00250
,167739,DB00321,10005557,40,7407,12,2838,0.535822629,1.277122948,0.655714871,2.678290182,0.692321422,DB0032110005557_,0.367704949,0.244609851,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,amitriptyline,DB00321
,167740,DB00273,10005750,57,8424,14,2179,1,1.053157803,0.578077453,2.050568101,1,DB0027310005750_,0,0.051793083,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,topiramate,DB00273
,167741,DB00285,10005750,96,10855,34,3684,0.839618246,0.958257272,0.64061268,1.464586877,0.917805277,DB0028510005750_,0.085770028,-0.042638986,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,venlafaxine,DB00285
,167762,DB00321,10027599,125,7322,19,2831,4.55327404901133e-05,2.543417315,1.558798963,4.374805552,0.000407847,DB0032110027599_,7.804617566,0.933508576,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,167763,DB01156,10027599,155,13467,19,6309,1.31854604063968e-10,3.82124595,2.36353727,6.524794407,4.21117651011107e-09,DB0115610027599_,19.28552377,1.340576534,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,167789,DB00537,10073508,28,7529,34,4264,0.003266923,0.466424439,0.27204813,0.793739891,0.014501572,DB0053710073508_,4.233498209,-0.762659247,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,ciprofloxacin,DB00537
,167790,DB00472,10006451,97,10662,16,4296,0.000352488,2.442577873,1.428597731,4.447839172,0.002306483,DB0047210006451_,6.072031212,0.893053987,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,fluoxetine,DB00472
,167791,DB00727,10006451,48,3795,14,4159,2.46274960256119e-06,3.757146171,2.033424386,7.390816521,3.1751147319382e-05,DB0072710006451_,10.3575817,1.323659672,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,nitroglycerin,DB00727
,167795,DB00695,10007815,43,28006,19,20509,0.071625186,1.657306031,0.945024,3.012325283,0.164109835,DB0069510007815_,1.807219352,0.505193411,NA,10007815,Catheterisation cardiac,10022891,Investigations,Inv,furosemide,DB00695
,167801,DB00230,10062355,78,19596,26,8625,0.241543743,1.320366623,0.836896428,2.146529659,0.399630677,DB0023010062355_,0.917214465,0.277909443,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,167803,DB01136,10062355,76,9808,56,11059,0.017908349,1.530199852,1.06811452,2.203691519,0.056660517,DB0113610062355_,2.870677662,0.425398349,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,167804,DB00051,10011732,49,25682,14,11406,0.171504763,1.554420076,0.84411454,3.050053768,0.312823575,DB0005110011732_,1.162115907,0.441102535,NA,10011732,Cyst,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,167815,DB00051,10062016,47,25684,14,11406,0.212589001,1.490879708,0.806557837,2.933431569,0.364531404,DB0005110062016_,1.009142575,0.399366354,NA,10062016,Immunosuppression,10021428,Immune system disorders,Immun,adalimumab,DB00051
,167827,DB00433,10007515,31,7625,30,5990,0.439660261,0.811775946,0.474730568,1.38988718,0.607995262,DB0043310007515_,0.497588189,-0.208530905,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,prochlorperazine,DB00433
,167829,DB01222,10007515,35,9239,30,5375,0.123204744,0.678780016,0.404300143,1.145921242,0.245950991,DB0122210007515_,1.402622987,-0.387458186,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,budesonide,DB01222
,167831,DB00381,10015916,65,29295,18,22869,3.26247085454796e-05,2.818863096,1.651400186,5.050645501,0.000305501,DB0038110015916_,8.093558489,1.036333646,female,10015916,Eye disorder,10015919,Eye disorders,Eye,amlodipine,DB00381
,167832,DB00678,10015916,43,15556,11,10713,0.002056314,2.691976486,1.364379804,5.791236808,0.009948502,DB0067810015916_,4.610333286,0.990275677,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,losartan,DB00678
,167834,DB00381,10039203,65,29295,33,22854,0.052305764,1.536610998,0.995445792,2.413171461,0.129355695,DB0038110039203_,2.045189346,0.429579341,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,167837,DB08880,10003988,71,3267,13,796,0.405086793,1.330606302,0.725965195,2.634228907,0.574774972,DB0888010003988_,0.553776668,0.285634705,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,teriflunomide,DB08880
,167838,DB00193,10006002,109,19211,26,8676,0.002707336,1.893276491,1.224175008,3.029015966,0.012432273,DB0019310006002_,4.387459528,0.638308921,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,167841,DB00471,10006002,56,14133,10,5455,0.019337398,2.16140101,1.091560435,4.755524783,0.060198202,DB0047110006002_,2.810112798,0.770756627,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,167843,DB00641,10006002,54,14070,28,12447,0.026062983,1.706068093,1.061075065,2.799131561,0.075857104,DB0064110006002_,2.578903918,0.534191362,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,167847,DB00338,10015958,76,33598,29,22243,0.012236633,1.734964873,1.117170685,2.761800587,0.041806707,DB0033810015958_,3.174698509,0.550987167,NA,10015958,Eye pain,10015919,Eye disorders,Eye,omeprazole,DB00338
,167927,DB00381,10033664,38,29322,18,22869,0.081285336,1.646493031,0.916616768,3.065732604,0.180523429,DB0038110033664_,1.711894708,0.498647591,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,167929,DB00996,10033664,86,38867,22,22403,0.000409788,2.253176208,1.397037401,3.782037666,0.002615025,DB0099610033664_,5.946481696,0.812340869,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,167934,DB08896,10048959,28,795,31,1009,0.689753412,1.146271564,0.656506327,1.993315989,0.812888491,DB0889610048959_,0.207161336,0.136514557,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,regorafenib,DB08896
,167948,DB08931,10005750,39,6538,13,2433,0.87578715,1.116381362,0.582180496,2.283317323,0.946704443,DB0893110005750_,0.054768332,0.110092528,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,riociguat,DB08931
,167954,DB00476,10049119,50,17207,10,6167,0.105712119,1.792043144,0.897467312,3.966000001,0.219692891,DB0047610049119_,1.515524659,0.58335639,NA,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,167978,DB00563,10024968,34,46612,19,15329,0.078158193,0.588499461,0.326161351,1.092521315,0.175275741,DB0056310024968_,1.741394885,-0.530179269,NA,10024968,Lower respiratory tract infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,167979,DB08827,10025482,54,1108,16,566,0.069332201,1.723563434,0.961277953,3.256901223,0.160133289,DB0882710025482_,1.831748756,0.544393912,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,lomitapide,DB08827
,167987,DB01610,10011831,49,892,79,1139,0.232577402,0.792089902,0.536916141,1.158914691,0.389034375,DB0161010011831_,0.944087572,-0.23308038,NA,10011831,Cytomegalovirus infection,10021881,Infections and infestations,Infec,valganciclovir,DB01610
,168001,DB00338,10002544,62,33612,19,22253,0.00289664,2.16035439,1.274357922,3.826962476,0.0131352,DB0033810002544_,4.332459652,0.770272278,NA,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,168006,DB00470,10010774,33,886,21,932,0.096597581,1.65256329,0.920042255,3.030459093,0.205706354,DB0047010010774_,1.581305591,0.502327591,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,dronabinol,DB00470
,168033,DB11089,10013538,43,10132,22,8385,0.079819889,1.617490566,0.945555115,2.841725965,0.178111615,DB1108910013538_,1.725344874,0.480875915,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,docusate,DB11089
,168038,DB00813,10013911,33,10539,23,10145,0.284262848,1.381117379,0.786212647,2.465180381,0.448732747,DB0081310013911_,0.801327787,0.322892867,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,168043,DB11089,10019063,59,10116,106,8301,8.93341923798789e-07,0.456754344,0.32595919,0.634744573,1.29767850052783e-05,DB1108910019063_,11.25234857,-0.783609574,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,docusate,DB11089
,168045,DB00641,10021789,105,14019,76,12399,0.203904263,1.221916833,0.900009827,1.665537151,0.353674017,DB0064110021789_,1.039379646,0.200420801,NA,10021789,Infection,10021881,Infections and infestations,Infec,simvastatin,DB00641
,168046,DB00706,10021789,6,1069,144,15781,0.310616378,0.615094105,0.221528264,1.376534206,0.478032232,DB0070610021789_,0.738077118,-0.485980007,NA,10021789,Infection,10021881,Infections and infestations,Infec,tamsulosin,DB00706
,168053,DB11365,10033371,65,1580,47,1501,0.177974947,1.313714778,0.882500475,1.9683917,0.321298254,DB1136510033371_,1.135385447,0.272858832,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sennosides,DB11365
,168074,DB00741,10001367,41,4053,34,3140,0.815326163,0.934256178,0.576957385,1.521648853,0.900928983,DB0074110001367_,0.104328844,-0.068004598,NA,10001367,Adrenal insufficiency,10014698,Endocrine disorders,Endo,hydrocortisone,DB00741
,168086,DB00268,10003988,76,2899,12,1533,1.91555574745428e-05,3.348385888,1.802580445,6.786077884,0.000192324,DB0026810003988_,8.55632991,1.208478405,female,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ropinirole,DB00268
,168090,DB00268,10009033,40,2935,16,1529,0.39921964,1.302341535,0.710454944,2.499485616,0.569076614,DB0026810009033_,0.563740207,0.264163825,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ropinirole,DB00268
,168095,DB01156,10009033,66,13556,15,6313,0.011446624,2.049006935,1.155934943,3.868887307,0.039669655,DB0115610009033_,3.227168734,0.717355254,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,168097,DB01273,10009033,48,1992,16,1259,0.027109614,1.895747036,1.052263448,3.592892364,0.078249185,DB0127310009033_,2.547856871,0.639612975,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,varenicline,DB01273
,168098,DB00231,10011224,64,3232,21,2118,0.005002294,1.996933732,1.199202568,3.453803096,0.020477388,DB0023110011224_,3.888434028,0.69161287,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,temazepam,DB00231
,168102,DB00231,10012378,65,3231,27,2112,0.052483255,1.57351878,0.986599664,2.573284516,0.129666724,DB0023110012378_,2.042787781,0.453314373,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,temazepam,DB00231
,168107,DB00203,10012442,93,13785,27,8911,0.000152638,2.226504447,1.435962054,3.559098639,0.001144024,DB0020310012442_,6.773203191,0.800432843,NA,10012442,Dermatitis contact,10040785,Skin and subcutaneous tissue disorders,Skin,sildenafil,DB00203
,168110,DB00316,10012442,37,65437,24,36929,0.595832497,0.870037043,0.50670634,1.520435981,0.741353207,DB0031610012442_,0.299278105,-0.13921949,NA,10012442,Dermatitis contact,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,168125,DB01240,10013709,57,5694,19,1557,0.48244131,0.820360598,0.479082896,1.464928645,0.646843021,DB0124010013709_,0.435651639,-0.198011281,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,168128,DB01212,10013968,99,1920,60,1881,0.004463706,1.616281563,1.153331344,2.280994551,0.018654663,DB0121210013968_,3.981659119,0.480128179,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ceftriaxone,DB01212
,168155,DB00196,10016322,58,5025,21,3264,0.020544968,1.793882192,1.070037026,3.118339129,0.063134912,DB0019610016322_,2.762481376,0.584382094,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,168156,DB00268,10016322,74,2901,21,1524,0.011740865,1.850958099,1.122152539,3.178005865,0.040459997,DB0026810016322_,3.207441509,0.615703396,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,168158,DB00836,10016322,67,5468,22,4053,0.000742172,2.257158218,1.373755503,3.845326773,0.004296442,DB0083610016322_,5.44996795,0.814106596,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,168216,DB00196,10018884,46,5037,45,3240,0.051751566,0.657588164,0.425293699,1.017244579,0.128323184,DB0019610018884_,2.053203319,-0.419176435,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,fluconazole,DB00196
,168218,DB00868,10018884,36,2948,15,1631,0.38202233,1.327737669,0.706489165,2.618513999,0.552153136,DB0086810018884_,0.59392985,0.283476493,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,benzonatate,DB00868
,168220,DB01156,10018884,59,13563,28,6300,0.908546989,0.978766381,0.613575439,1.595895865,0.959033459,DB0115610018884_,0.041829315,-0.021462295,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,bupropion,DB01156
,168235,DB00868,10021097,64,2920,30,1616,0.514176028,1.180629505,0.750321493,1.895765903,0.674188356,DB0086810021097_,0.394245747,0.166047775,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,benzonatate,DB00868
,168238,DB00334,10021143,27,2822,32,2780,0.514542012,0.831220801,0.477695808,1.436362575,0.674483183,DB0033410021143_,0.393808536,-0.184859814,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,olanzapine,DB00334
,168239,DB00741,10021143,32,4062,33,3141,0.259926726,0.749869314,0.445328863,1.261183631,0.421180161,DB0074110021143_,0.8646946,-0.287856336,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrocortisone,DB00741
,168240,DB00836,10021143,51,5484,36,4039,0.913373213,1.043385099,0.666382029,1.649186303,0.961224147,DB0083610021143_,0.039547654,0.04247033,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loperamide,DB00836
,168242,DB00868,10021143,51,2933,29,1617,0.906513164,0.969532288,0.600260513,1.593204006,0.958224861,DB0086810021143_,0.042672809,-0.030941501,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,benzonatate,DB00868
,168244,DB01156,10021143,61,13561,23,6305,0.41392424,1.233054487,0.751335766,2.089701685,0.583252849,DB0115610021143_,0.539134483,0.209494414,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,168245,DB01212,10021143,33,1986,26,1915,0.512298007,1.223791444,0.706891135,2.139339313,0.672497471,DB0121210021143_,0.396756928,0.201953781,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ceftriaxone,DB01212
,168250,DB00868,10021789,36,2948,19,1627,1,1.045697225,0.581949621,1.936682319,1,DB0086810021789_,0,0.044683864,NA,10021789,Infection,10021881,Infections and infestations,Infec,benzonatate,DB00868
,168253,DB01409,10021789,54,5977,23,3943,0.080380932,1.548784776,0.932813665,2.648817553,0.179044346,DB0140910021789_,1.720121761,0.437470608,NA,10021789,Infection,10021881,Infections and infestations,Infec,tiotropium,DB01409
,168255,DB00868,10025482,109,2875,37,1609,0.008340903,1.648539827,1.119631055,2.475782647,0.030777094,DB0086810025482_,3.480984556,0.499889943,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,benzonatate,DB00868
,168266,DB09140,10027599,54,3687,10,1788,0.002944032,2.618341697,1.316183236,5.780882265,0.01329734,DB0914010027599_,4.320191287,0.962541177,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,oxygen,DB09140
,168290,DB00695,10031123,46,28003,32,20496,0.908801104,1.052144174,0.655463968,1.70783382,0.95913476,DB0069510031123_,0.041723693,0.050830153,NA,10031123,Orthopnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,168403,DB01156,10038435,58,13564,40,6288,0.063687097,0.672196775,0.441104937,1.033441804,0.150102249,DB0115610038435_,1.896438556,-0.397204161,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,bupropion,DB01156
,168404,DB09140,10038435,62,3679,26,1772,0.646387508,1.148518809,0.712892433,1.898884471,0.781846011,DB0914010038435_,0.246097475,0.13847312,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,oxygen,DB09140
,168405,DB00169,10042604,38,38653,15,18160,0.659303218,1.190195287,0.639446463,2.32972808,0.791856756,DB0016910042604_,0.233374768,0.1741174,NA,10042604,Supraventricular tachycardia,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,168407,DB00203,10042604,39,13839,18,8920,0.277876308,1.396516361,0.779537951,2.595306141,0.441554802,DB0020310042604_,0.817453139,0.333980822,NA,10042604,Supraventricular tachycardia,10007541,Cardiac disorders,Card,sildenafil,DB00203
,168472,DB00334,10047895,35,2814,34,2778,1,1.016241381,0.613604417,1.684792962,1,DB0033410047895_,0,0.016110901,NA,10047895,Weight decreased,10022891,Investigations,Inv,olanzapine,DB00334
,168474,DB00868,10047895,49,2935,49,1597,0.003743719,0.544177936,0.356858284,0.829820524,0.016167529,DB0086810047895_,4.124750441,-0.608478998,NA,10047895,Weight decreased,10022891,Investigations,Inv,benzonatate,DB00868
,168476,DB01273,10047895,36,2004,25,1250,0.691841373,0.89823497,0.521664079,1.569153852,0.814231687,DB0127310047895_,0.205510326,-0.107323586,NA,10047895,Weight decreased,10022891,Investigations,Inv,varenicline,DB01273
,168547,DB00695,10057362,58,27991,54,20474,0.213691042,0.785641342,0.532639159,1.160482054,0.365848306,DB0069510057362_,1.005536495,-0.241254899,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,168553,DB01175,10057362,31,10693,20,4872,0.228553589,0.706223812,0.389469307,1.308815157,0.384100961,DB0117510057362_,0.956849843,-0.347823078,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,168582,DB00196,10061623,36,5047,27,3258,0.60496627,0.860728869,0.507090067,1.477160682,0.748166858,DB0019610061623_,0.290129253,-0.149975726,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,168583,DB00203,10061623,39,13839,31,8907,0.392396213,0.80972594,0.491933783,1.343291195,0.562307998,DB0020310061623_,0.57570554,-0.211059434,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,168585,DB00421,10061623,44,8859,21,5231,0.443704084,1.237197283,0.719150288,2.193142844,0.611768876,DB0042110061623_,0.491400721,0.212848566,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,168588,DB00836,10061623,40,5495,24,4051,0.449243445,1.228666334,0.72149878,2.134315617,0.616834119,DB0083610061623_,0.483155142,0.2059293,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,168597,DB00741,10061822,33,4061,17,3157,0.198056381,1.508975522,0.814978568,2.894109856,0.346702538,DB0074110061822_,1.059288105,0.411430958,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,hydrocortisone,DB00741
,168602,DB01240,10061822,55,5696,19,1557,0.393439919,0.791302585,0.460711293,1.416324482,0.563358298,DB0124010061822_,0.573839445,-0.23407485,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,168634,DB11065,10016256,122,3064,84,2604,0.154623426,1.234289124,0.922362841,1.658134214,0.290284748,DB1106510016256_,1.236892949,0.210495196,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pancrelipase amylase,DB11065
,168635,DB01050,10016807,67,18041,13,9358,0.00053062,2.673254124,1.461315178,5.281456566,0.003239049,DB0105010016807_,5.732475393,0.983296503,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,ibuprofen,DB01050
,168639,DB11065,10047895,89,3097,87,2601,0.356704566,0.859175757,0.629040722,1.173803848,0.526375431,DB1106510047895_,0.641740574,-0.151781771,NA,10047895,Weight decreased,10022891,Investigations,Inv,pancrelipase amylase,DB11065
,168680,DB00476,10006784,92,17165,29,6148,0.605705064,1.136257261,0.740551198,1.791514119,0.748782165,DB0047610006784_,0.289307173,0.127739757,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,168681,DB08868,10006784,69,9133,20,2491,0.795852591,0.940975522,0.563872649,1.637977901,0.889450459,DB0886810006784_,0.117151469,-0.060838152,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,168694,DB00512,10020919,38,4699,24,5074,0.041414531,1.709582966,0.997569021,2.984331957,0.108575798,DB0051210020919_,2.220306753,0.536249461,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,vancomycin,DB00512
,168703,DB00374,10005750,90,17626,19,5705,0.094070442,1.533107267,0.926218251,2.666563548,0.201861543,DB0037410005750_,1.600173249,0.427296569,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,treprostinil,DB00374
,168704,DB00678,10007882,79,15520,52,10672,0.858700643,1.044670248,0.726278099,1.513703673,0.932799372,DB0067810007882_,0.069565137,0.043701284,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,losartan,DB00678
,168709,DB00678,10043554,64,15535,70,10654,0.007990529,0.627050744,0.43925593,0.893758246,0.02975787,DB0067810043554_,3.514661645,-0.466727811,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,losartan,DB00678
,168710,DB06724,10008479,128,7801,43,3876,0.026964364,1.478977683,1.036967648,2.145749717,0.077945488,DB0672410008479_,2.551745572,0.391351094,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,168711,DB00678,10016334,45,15554,20,10704,0.128684353,1.548385689,0.895159617,2.76978882,0.253754017,DB0067810016334_,1.371389919,0.437212897,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,168714,DB06724,10037087,161,7768,40,3879,3.96364723906971e-05,2.009805063,1.410599182,2.923773911,0.000361563,DB0672410037087_,7.925073401,0.698037734,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,calcium carbonate,DB06724
,168715,DB01261,10037844,81,3700,70,3233,1,1.011091781,0.722516303,1.417905815,1,DB0126110037844_,0,0.011030719,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sitagliptin,DB01261
,168716,DB06724,10046735,57,7872,16,3903,0.045556123,1.766239501,0.998753198,3.299741139,0.116635922,DB0672410046735_,2.148697974,0.568852711,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,calcium carbonate,DB06724
,168757,DB00999,10020583,69,21361,59,12180,0.026743423,0.666879037,0.46386995,0.961302071,0.077436211,DB0099910020583_,2.558300766,-0.405146603,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,168758,DB00682,10053505,57,19402,7,16357,3.2495515349067e-09,6.864597859,3.124032624,17.84105715,8.15023493273116e-08,DB0068210053505_,16.32263399,1.926377459,female,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,168762,DB00682,10065464,40,19419,11,16353,0.000586425,3.062019262,1.541427725,6.618302046,0.003527677,DB0068210065464_,5.647115768,1.119074588,female,10065464,Infusion site haemorrhage,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,168793,DB00310,10013709,36,908,34,747,0.624452244,0.871152093,0.524153387,1.450556907,0.764282326,DB0031010013709_,0.268818022,-0.137938699,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,chlorthalidone,DB00310
,168826,DB00843,10017955,26,2168,30,2143,0.59273292,0.856704005,0.484904868,1.504295407,0.738895678,DB0084310017955_,0.302598535,-0.154662805,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,donepezil,DB00843
,168828,DB01267,10028813,32,2820,32,3683,0.311652632,1.305963365,0.772607983,2.207548798,0.479038006,DB0126710028813_,0.73597534,0.266940979,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,paliperidone,DB01267
,168838,DB08904,10058080,56,11554,13,3546,0.475964598,1.32202602,0.713033134,2.638448262,0.641432955,DB0890410058080_,0.444050613,0.279165423,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,168859,DB00921,10044565,73,5772,45,4858,0.113986097,1.365301,0.927065494,2.030171354,0.232149741,DB0092110044565_,1.460372682,0.311374917,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,buprenorphine,DB00921
,168914,DB01285,10020772,40,1236,25,584,0.282579722,0.756075353,0.44280348,1.31376963,0.446679375,DB0128510020772_,0.805914224,-0.279614235,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,corticotropin,DB01285
,168944,DB01202,10027599,63,6651,22,5696,0.000173146,2.452205531,1.486081152,4.190943776,0.001277336,DB0120210027599_,6.662978781,0.896987836,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,168945,DB00316,10009900,73,65401,44,36909,0.772745913,0.936307925,0.635330475,1.394065206,0.875652109,DB0031610009900_,0.132786403,-0.065810876,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,168961,DB00526,10035664,25,1573,35,1859,0.601564491,0.844196946,0.482068214,1.458418611,0.745837251,DB0052610035664_,0.293247865,-0.169369463,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,oxaliplatin,DB00526
,168976,DB00698,10002034,44,3104,12,417,0.036954214,0.492708591,0.253281287,1.033431767,0.099492114,DB0069810002034_,2.307676895,-0.707837373,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,nitrofurantoin,DB00698
,168986,DB00177,10020751,69,4731,22,2828,0.008770142,1.874649041,1.142723102,3.189930192,0.032054953,DB0017710020751_,3.440303567,0.628421464,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,valsartan,DB00177
,169001,DB00060,10061818,48,9460,18,2447,0.172131787,0.689805838,0.3931177,1.262423811,0.313644867,DB0006010061818_,1.15949393,-0.371345116,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,169002,DB00472,10001497,78,10681,63,4249,4.817027629012e-05,0.492534621,0.348179399,0.699199874,0.000428045,DB0047210001497_,7.756283332,-0.708190525,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,169004,DB00916,10016322,38,5285,12,2419,0.288098948,1.449370312,0.73981538,3.05218872,0.45310123,DB0091610016322_,0.791639714,0.371129195,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,169009,DB06724,10020751,85,7844,16,3903,0.000114277,2.643201037,1.535034731,4.839446306,0.000894512,DB0672410020751_,7.019232641,0.971990697,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,calcium carbonate,DB06724
,169012,DB00341,10010264,224,11181,61,5007,0.000452266,1.644384098,1.231308548,2.224548387,0.002841006,DB0034110010264_,5.863597038,0.497365905,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,169015,DB01097,10047899,72,6193,7,1496,0.014627257,2.484467507,1.142762625,6.413130777,0.048328507,DB0109710047899_,3.029733685,0.910058354,NA,10047899,Weight increased,10022891,Investigations,Inv,leflunomide,DB01097
,169016,DB01592,10047899,131,6145,43,3024,0.022310884,1.499150528,1.051662719,2.174191755,0.067318094,DB0159210047899_,2.698326219,0.404898633,NA,10047899,Weight increased,10022891,Investigations,Inv,iron,DB01592
,169018,DB00028,10047895,116,13342,45,5570,0.72871785,1.076162212,0.755420815,1.55636441,0.841846954,DB0002810047895_,0.172157046,0.073401205,NA,10047895,Weight decreased,10022891,Investigations,Inv,human immunoglobulin g,DB00028
,169032,DB00316,10037162,195,65279,63,36890,7.00256817517926e-05,1.74914877,1.309954171,2.363108728,0.000587121,DB0031610037162_,7.440279241,0.559129253,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,169036,DB00047,10040829,40,9245,11,8507,0.000191166,3.345675683,1.683540238,7.234510462,0.001387299,DB0004710040829_,6.580396509,1.207668671,female,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,insulin glargine,DB00047
,169040,DB00437,10003246,45,6876,31,11515,0.000124746,2.430860727,1.503118531,3.977208611,0.000963686,DB0043710003246_,6.94474502,0.888245403,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,allopurinol,DB00437
,169041,DB00455,10003246,51,9350,12,5106,0.007656213,2.320791796,1.219249776,4.786290575,0.028757295,DB0045510003246_,3.54886382,0.841908419,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,169049,DB00423,10013700,131,2336,22,1018,1.11750309118108e-05,2.594343527,1.631639229,4.307885799,0.000119453,DB0042310013700_,9.03258498,0.953333508,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,methocarbamol,DB00423
,169067,DB01240,10033546,43,5708,16,1560,0.338477383,0.734529376,0.40410465,1.400938824,0.50752299,DB0124010033546_,0.678213269,-0.30852529,NA,10033546,Pallor,10047065,Vascular disorders,Vasc,epoprostenol,DB01240
,169069,DB00275,10037087,61,1999,22,1215,0.038570443,1.685025673,1.013849649,2.897357501,0.10278543,DB0027510037087_,2.275111671,0.5217808,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,olmesartan,DB00275
,169074,DB00668,10044565,80,10011,21,4282,0.049202259,1.629396048,0.995971356,2.778642167,0.123481298,DB0066810044565_,2.091665569,0.488209424,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,epinephrine,DB00668
,169085,DB13961,10017944,37,9420,26,6388,0.898211292,0.96501443,0.568189016,1.661563894,0.956353692,DB1396110017944_,0.044627464,-0.035612224,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,169100,DB08880,10047513,48,3290,12,797,0.870584351,0.969001703,0.50412579,2.013742104,0.94263098,DB0888010047513_,0.059080399,-0.03148891,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,teriflunomide,DB08880
,169113,DB00175,10005724,44,8087,14,6092,0.003362326,2.367378067,1.271884276,4.681611966,0.014825644,DB0017510005724_,4.211396926,0.861783042,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,pravastatin,DB00175
,169114,DB00455,10005724,42,9359,14,5104,0.123426319,1.63602074,0.874845673,3.246757874,0.246281089,DB0045510005724_,1.401281758,0.492266915,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,loratadine,DB00455
,169117,DB00338,10056819,137,33537,63,22209,0.016817428,1.440064297,1.060500363,1.973871575,0.053937659,DB0033810056819_,2.919926362,0.364687763,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,169118,DB00695,10056819,81,27968,33,20495,0.004222051,1.798666497,1.185728138,2.78515915,0.017844766,DB0069510056819_,4.026045015,0.587045555,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,169120,DB00904,10056819,81,22988,42,14414,0.353737106,1.209216793,0.822580799,1.80085309,0.523593864,DB0090410056819_,0.647038963,0.189972872,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,169123,DB00213,10013887,27,18868,40,13381,0.002823866,0.478708399,0.282390569,0.800039511,0.012864007,DB0021310013887_,4.353322006,-0.736663638,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,169124,DB00480,10013887,32,67396,28,67634,0.60825033,1.146891002,0.66884237,1.977197793,0.751004906,DB0048010013887_,0.286343095,0.137054805,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,169136,DB00540,10010144,183,2300,95,996,0.175205819,0.834238903,0.640017941,1.092773439,0.317728535,DB0054010010144_,1.146557926,-0.181235463,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,nortriptyline,DB00540
,169137,DB00996,10010144,1257,37696,760,21665,0.279552745,0.950577845,0.866638299,1.04317854,0.443392025,DB0099610010144_,0.813300968,-0.050685221,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,169176,DB00635,10028116,67,32986,96,23698,1.47511611905119e-05,0.50140016,0.361225985,0.692524036,0.000152711,DB0063510028116_,8.786960622,-0.690350773,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,169204,DB00635,10034474,82,32971,41,23753,0.055246465,1.440831573,0.978395333,2.151359295,0.134770611,DB0063510034474_,2.004181126,0.365220428,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,prednisone,DB00635
,169240,DB00581,10047942,34,2079,25,2044,0.295756505,1.337007806,0.771444296,2.346663048,0.461568041,DB0058110047942_,0.773125802,0.290434137,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,lactulose,DB00581
,169244,DB11365,10047942,42,1603,31,1517,0.343557227,1.282050571,0.782423477,2.121384485,0.512872453,DB1136510047942_,0.667728094,0.248460804,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,sennosides,DB11365
,169304,DB00544,10042128,34,2401,31,2622,0.532558244,1.197681846,0.711829201,2.021941673,0.689367351,DB0054410042128_,0.371980984,0.180387893,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,fluorouracil,DB00544
,169323,DB08906,10028813,140,2053,38,1120,9.4239516033581e-05,2.009520228,1.383796054,2.979348983,0.00075775,DB0890610028813_,7.185156667,0.697896001,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,fluticasone furoate,DB08906
,169352,DB09053,10003988,39,2246,44,4008,0.038844972,1.581673673,0.997532815,2.499084892,0.103323224,DB0905310003988_,2.269893107,0.458483573,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ibrutinib,DB09053
,169374,DB00688,10067482,60,6430,18,5360,5.34197240511083e-05,2.778332256,1.615831113,5.006398443,0.000467079,DB0068810067482_,7.669012951,1.02185084,female,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,169376,DB00126,10016288,23,10148,35,5910,0.000322472,0.382729796,0.215715938,0.667030337,0.002140452,DB0012610016288_,6.146738392,-0.960426032,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,ascorbic acid,DB00126
,169378,DB00126,10029354,75,10096,56,5889,0.172885832,0.781232743,0.544411355,1.12664951,0.314637131,DB0012610029354_,1.156335268,-0.246882168,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,ascorbic acid,DB00126
,169380,DB01175,10029354,60,10664,33,4859,0.37250128,0.828473886,0.532209222,1.309977156,0.542208225,DB0117510029354_,0.612105172,-0.188169962,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,escitalopram,DB01175
,169415,DB00480,10017076,54,67374,33,67629,0.024348784,1.642540976,1.045878634,2.615455915,0.072064478,DB0048010017076_,2.630194033,0.496244418,NA,10017076,Fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,169420,DB00564,10003239,30,2574,24,1439,0.200632601,0.698906992,0.393302753,1.254350477,0.349747871,DB0056410003239_,1.050542752,-0.358237604,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,carbamazepine,DB00564
,169427,DB00999,10003983,43,21387,29,12210,0.539936211,0.846529619,0.516183536,1.4067703,0.695563736,DB0099910003983_,0.363032631,-0.166610089,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,169430,DB00316,10023204,47,65427,21,36932,0.448698223,1.263381603,0.740333008,2.225422746,0.616307993,DB0031610023204_,0.484008452,0.233791938,NA,10023204,Joint dislocation,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,169445,DB01156,10022998,107,13515,51,6277,0.864135246,0.974406173,0.690824759,1.390151259,0.937540552,DB0115610022998_,0.064495267,-0.025927047,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,169449,DB00928,10043554,25,810,32,1254,0.494292155,1.209370917,0.681647019,2.123572158,0.656818711,DB0092810043554_,0.420347234,0.190100321,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,azacitidine,DB00928
,169497,DB00198,10033371,44,1231,11,992,0.000271518,3.221849079,1.626703849,6.956217594,0.001859522,DB0019810033371_,6.287435761,1.169955443,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,oseltamivir,DB00198
,169521,DB00203,10022004,101,13777,33,8905,0.00049239,1.978215602,1.322183736,3.029321985,0.003054992,DB0020310022004_,5.790978285,0.682195227,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,169524,DB08932,10052251,101,19342,22,6575,0.061149273,1.560528436,0.975723067,2.602465208,0.14555,DB0893210052251_,1.927235609,0.445024505,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,169527,DB00737,10000081,63,2738,14,918,0.184497407,1.508566095,0.831227672,2.930142614,0.329540251,DB0073710000081_,1.110056774,0.411159594,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,meclizine,DB00737
,169535,DB00669,10003988,98,6279,14,1083,0.591507501,1.207328888,0.683186421,2.298181898,0.737822975,DB0066910003988_,0.304051354,0.188410389,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sumatriptan,DB00669
,169558,DB00737,10049848,40,2761,11,921,0.629209702,1.21293317,0.607647022,2.63238488,0.76829847,DB0073710049848_,0.263576988,0.193041534,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,meclizine,DB00737
,169576,DB00678,10022061,87,15512,21,10703,2.93362245108574e-06,2.85836059,1.757671146,4.850822872,3.7134729654124e-05,DB0067810022061_,10.20095792,1.05024824,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,169585,DB00678,10037153,239,15360,145,10579,0.249766553,1.135261047,0.918284409,1.407330109,0.409309133,DB0067810037153_,0.893284581,0.126862622,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,losartan,DB00678
,169592,DB00678,10053425,53,15546,9,10715,1.20594139023331e-05,4.058694377,1.983677773,9.362616548,0.00012797,DB0067810053425_,8.963714683,1.40086134,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,169642,DB00540,10043071,42,2441,10,1081,0.094062984,1.85969354,0.913925358,4.172546941,0.201857006,DB0054010043071_,1.600195723,0.620411711,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,nortriptyline,DB00540
,169651,DB14500,10040753,159,7650,20,4053,1.44928656686334e-12,4.211384746,2.632199659,7.093288746,6.33851870382743e-11,DB1450010040753_,23.48179092,1.437791512,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,potassium,DB14500
,169707,DB00761,10005851,49,15258,29,8596,0.814520304,0.951919514,0.589019446,1.563944031,0.900515044,DB0076110005851_,0.104788409,-0.049274792,NA,10005851,Blood urea increased,10022891,Investigations,Inv,potassium chloride,DB00761
,169717,DB08889,10019211,87,3078,43,3842,4.2328895371281e-07,2.525137936,1.727031145,3.74055387,6.65041849870963e-06,DB0888910019211_,11.92083077,0.926295689,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,carfilzomib,DB08889
,169718,DB08889,10025482,107,3058,82,3803,0.001087911,1.622639056,1.200616358,2.199693871,0.005905768,DB0888910025482_,5.131825799,0.48405387,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,169723,DB00512,10044565,21,4716,31,5067,0.26949024,0.727863266,0.396951863,1.309962633,0.432055313,DB0051210044565_,0.83920166,-0.317642069,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,vancomycin,DB00512
,169729,DB00158,10029216,47,16768,13,8091,0.074165579,1.744482796,0.927871929,3.516728825,0.168476924,DB0015810029216_,1.780956491,0.55645812,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,folic acid,DB00158
,169730,DB00193,10031161,99,19221,27,8675,0.020224656,1.654847131,1.071184256,2.63718961,0.062340087,DB0019310031161_,2.775150615,0.503708637,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,169731,DB00641,10039073,81,14043,16,12459,4.90769442953543e-10,4.491150585,2.603854911,8.23417388,1.4429390165586e-08,DB0064110039073_,18.05399873,1.502108924,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,169733,DB00193,10040943,41,19279,16,8686,0.670293243,1.154500693,0.633577005,2.205202867,0.799993547,DB0019310040943_,0.223151617,0.14366795,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,169735,DB00153,10048334,52,7371,10,3429,0.008657966,2.418885608,1.214224148,5.345029179,0.031731978,DB0015310048334_,3.450430352,0.883306942,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,ergocalciferol,DB00153
,169745,DB00193,10052428,43,19277,9,8693,0.034935817,2.154497923,1.035354337,5.028940277,0.095302573,DB0019310052428_,2.350698466,0.767557714,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,169754,DB01222,10016825,63,9211,22,5383,0.041764109,1.673482343,1.014278056,2.859667738,0.109257984,DB0122210016825_,2.214043369,0.514906691,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,budesonide,DB01222
,169756,DB00115,10019304,37,18388,19,10453,0.781953049,1.107027258,0.620139732,2.039012033,0.881222599,DB0011510019304_,0.126445019,0.101678277,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,cyanocobalamin,DB00115
,169764,DB01222,10028735,94,9180,24,5381,0.000160112,2.295697825,1.451563485,3.764525168,0.001192898,DB0122210028735_,6.731369891,0.831036861,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,169768,DB00588,10029410,51,16473,20,8448,0.379396597,1.307762057,0.765473829,2.317369673,0.549400301,DB0058810029410_,0.598927958,0.268317323,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,169782,DB00186,10013990,42,16859,20,9988,0.510949753,1.244151407,0.713851602,2.238246244,0.671297542,DB0018610013990_,0.39854281,0.218453697,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,lorazepam,DB00186
,169783,DB00203,10013990,41,13837,20,8918,0.358475918,1.321215422,0.755946926,2.381884031,0.528169626,DB0020310013990_,0.638337786,0.278552087,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,sildenafil,DB00203
,169793,DB00451,10027566,54,47217,13,15406,0.394634987,1.355297216,0.72967398,2.708018544,0.564546676,DB0045110027566_,0.571732212,0.304020778,NA,10027566,Micturition urgency,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,169795,DB00203,10036018,40,13838,22,8916,0.603775896,1.171429235,0.679178516,2.071041258,0.747337482,DB0020310036018_,0.291238412,0.158224571,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,sildenafil,DB00203
,169821,DB00331,10016100,30,24916,24,20728,1,1.039900099,0.587553765,1.859346993,1,DB0033110016100_,0,0.03912465,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,169828,DB00331,10054236,34,24912,20,20732,0.273830607,1.414742744,0.791067372,2.594677127,0.436887671,DB0033110054236_,0.828079162,0.346947708,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,metformin,DB00331
,169834,DB08895,10028034,111,28003,15,6631,0.040529565,1.752248235,1.016967668,3.238274769,0.106702685,DB0889510028034_,2.23770896,0.560899669,NA,10028034,Mouth ulceration,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,169842,DB00264,10051118,68,29539,42,24850,0.125420811,1.36203122,0.913398534,2.052203437,0.249248555,DB0026410051118_,1.389304669,0.30897713,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,169849,DB00199,10000059,62,2648,7,693,0.033787143,2.317595131,1.05398692,6.029502613,0.092945584,DB0019910000059_,2.375741071,0.840530066,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,erythromycin,DB00199
,169889,DB01268,10068319,32,2111,28,3102,0.047775574,1.679149231,0.976164551,2.903944922,0.120916755,DB0126810068319_,2.112652949,0.518287255,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sunitinib,DB01268
,169895,DB00451,10043431,78,47193,7,15412,0.000200854,3.639012607,1.684544564,9.349699542,0.001446028,DB0045110043431_,6.538934926,1.291712383,female,10043431,Thinking abnormal,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,169896,DB00490,10016256,252,3818,95,1481,0.853122858,1.028972146,0.802974232,1.327157753,0.928236374,DB0049010016256_,0.074468865,0.028560388,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,169897,DB08882,10016256,47,950,39,954,0.440553551,1.210084543,0.766683718,1.919322114,0.608926228,DB0888210016256_,0.496058155,0.190690228,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,linagliptin,DB08882
,169918,DB00169,10000084,48,38643,20,18155,0.698260093,1.127544689,0.65641882,2.006171555,0.81852413,DB0016910000084_,0.200252402,0.120042427,NA,10000084,Abdominal pain lower,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,169939,DB00588,10016766,65,16459,28,8440,0.510427499,1.190374993,0.752762169,1.927588936,0.670829341,DB0058810016766_,0.39924051,0.174268378,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,169963,DB01394,10038435,28,1412,34,1969,0.605177288,1.148342315,0.667440223,1.961134108,0.7483222,DB0139410038435_,0.289921644,0.138319438,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,colchicine,DB01394
,169966,DB00656,10061920,27,11986,35,6584,0.000801982,0.4237684,0.246456377,0.721329853,0.004585123,DB0065610061920_,5.384938395,-0.8585682,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,169999,DB00158,10023469,68,16747,20,8084,0.052546832,1.641195489,0.983896558,2.855441625,0.129794217,DB0015810023469_,2.041805032,0.495424933,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,folic acid,DB00158
,170002,DB00338,10023469,62,33612,16,22256,0.000437919,2.565757049,1.462175048,4.76488591,0.00276434,DB0033810023469_,5.890953281,0.942253581,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,omeprazole,DB00338
,170011,DB00321,10047895,101,7346,39,2811,1,0.990984856,0.676618605,1.477178481,1,DB0032110047895_,0,-0.009056027,NA,10047895,Weight decreased,10022891,Investigations,Inv,amitriptyline,DB00321
,170022,DB00820,10028391,121,11794,37,5779,0.010658347,1.60237666,1.098985675,2.386151604,0.037456333,DB0082010028391_,3.284579485,0.47148794,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,170098,DB00836,10033295,98,5437,148,3927,2.00277695566483e-08,0.478293528,0.365440595,0.623745189,4.19242210213827e-07,DB0083610033295_,14.68481702,-0.73753066,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,loperamide,DB00836
,170103,DB00490,10047700,124,3946,34,1542,0.072173863,1.425156592,0.963331565,2.15887481,0.165064822,DB0049010047700_,1.801417024,0.354281697,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,buspirone,DB00490
,170108,DB00761,10003553,80,15227,14,8611,7.24283141635522e-06,3.231344151,1.816689074,6.179864154,8.18125585642015e-05,DB0076110003553_,9.411079798,1.172898197,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,170109,DB00814,10003553,47,8240,6,3409,0.00350885,3.240836268,1.380950988,9.282997105,0.015349942,DB0081410003553_,4.17664356,1.175831404,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,meloxicam,DB00814
,170110,DB01409,10005750,41,5990,20,3946,0.295709519,1.350427636,0.771911225,2.43684806,0.461522116,DB0140910005750_,0.773225304,0.30042131,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,tiotropium,DB01409
,170119,DB00588,10037423,75,16449,37,8431,0.920412246,1.03896069,0.691201623,1.586247148,0.964788479,DB0058810037423_,0.035846395,0.038220877,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,170176,DB01065,10033557,44,4287,9,3042,0.00021072,3.468576268,1.668004795,8.093652027,0.001505308,DB0106510033557_,6.498757713,1.243744212,female,10033557,Palpitations,10007541,Cardiac disorders,Card,melatonin,DB01065
,170193,DB01065,10037087,87,4244,31,3020,0.000664743,1.996866201,1.307574974,3.122586888,0.003928672,DB0106510037087_,5.539453799,0.691579052,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,melatonin,DB01065
,170211,DB00829,10047513,87,7965,22,4432,0.000577339,2.200322151,1.363373164,3.695626118,0.003479875,DB0082910047513_,5.660758808,0.788603782,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,diazepam,DB00829
,170218,DB00829,10052904,64,7988,20,4434,0.02239506,1.776189417,1.059238536,3.103385815,0.067497106,DB0082910052904_,2.695670557,0.574470292,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,diazepam,DB00829
,170225,DB00927,10061822,35,7462,20,4996,0.679488453,1.17162052,0.657052421,2.144634326,0.806114837,DB0092710061822_,0.215529069,0.15838785,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,170226,DB01065,10061822,39,4292,11,3040,0.00569172,2.510926961,1.258679966,5.445099735,0.022695214,DB0106510061822_,3.785601225,0.920651992,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,170231,DB08889,10013709,83,3082,80,3805,0.130003287,1.280831637,0.927094796,1.770334923,0.255725829,DB0888910013709_,1.363649387,0.247509583,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,170255,DB00395,10070863,197,1987,81,655,0.127021695,0.801768081,0.606208452,1.067814027,0.251469855,DB0039510070863_,1.380432158,-0.220935889,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,carisoprodol,DB00395
,170266,DB01075,10000891,32,19916,26,11071,0.170000796,0.684204428,0.394795419,1.195942341,0.310893405,DB0107510000891_,1.168305174,-0.379498535,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,170270,DB00153,10018838,33,7390,17,3422,0.760936057,0.898891191,0.485740364,1.72323063,0.867392526,DB0015310018838_,0.142263665,-0.106593285,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,ergocalciferol,DB00153
,170284,DB00169,10034972,48,38643,19,18156,0.600930208,1.186944631,0.68458087,2.138947413,0.745279349,DB0016910034972_,0.293996166,0.171382469,NA,10034972,Photosensitivity reaction,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,170294,DB00065,10003246,54,9410,13,4944,0.009508685,2.182321546,1.173962634,4.363483142,0.03419796,DB0006510003246_,3.375589277,0.780389239,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,infliximab,DB00065
,170298,DB00921,10046735,89,5756,43,4860,0.002678505,1.747487862,1.198605411,2.582201643,0.012324639,DB0092110046735_,4.396154859,0.558179249,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,buprenorphine,DB00921
,170316,DB00213,10039117,42,18853,30,13391,1,0.994398413,0.60741755,1.646313951,1,DB0021310039117_,0,-0.005617335,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,170318,DB00381,10039117,52,29308,43,22844,0.836166296,0.942607631,0.61692226,1.446811905,0.915356757,DB0038110039117_,0.088441391,-0.059105169,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,170328,DB01224,10042772,48,8060,30,5887,0.5659505,1.168601404,0.724527042,1.912748823,0.717434719,DB0122410042772_,0.332073319,0.155807652,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,170357,DB00471,10013538,45,14144,9,5456,0.069119939,1.928700889,0.930221656,4.490661152,0.159769387,DB0047110013538_,1.834023835,0.656846662,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,montelukast,DB00471
,170362,DB00863,10013538,37,10636,13,5827,0.18434596,1.559244129,0.809276449,3.199487892,0.329336882,DB0086310013538_,1.110674093,0.444201171,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,ranitidine,DB00863
,170369,DB00028,10013700,60,13398,11,5604,0.00872427,2.281399205,1.187293712,4.816885937,0.03193169,DB0002810013700_,3.444156351,0.824788941,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,human immunoglobulin g,DB00028
,170490,DB00153,10037884,42,7381,18,3421,0.889532256,1.081461282,0.60813597,1.998999068,0.954089642,DB0015310037884_,0.046997648,0.078313166,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,ergocalciferol,DB00153
,170491,DB00788,10037884,47,9309,22,5039,0.615176848,1.156396042,0.682301436,2.017496046,0.756576135,DB0078810037884_,0.278952109,0.145308308,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,naproxen,DB00788
,170496,DB06403,10046306,134,21337,24,6637,0.011038504,1.736639264,1.117670379,2.807743452,0.038509135,DB0640310046306_,3.256859797,0.551951788,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,170501,DB00959,10067482,37,8041,22,4980,1,1.041593629,0.597708881,1.855971271,1,DB0095910067482_,0,0.040751876,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,170502,DB01281,10053762,155,8777,42,1756,0.100834839,0.738371222,0.519818915,1.068941632,0.212103372,DB0128110053762_,1.550681518,-0.30330857,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,abatacept,DB01281
,170503,DB01281,10067482,65,8867,12,1786,0.87905283,1.090985659,0.582614091,2.224100937,0.949141622,DB0128110067482_,0.052197259,0.087081562,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,170506,DB01060,10047924,31,8556,35,5046,0.010157409,0.522371825,0.311099755,0.873383858,0.036008834,DB0106010047924_,3.323990981,-0.649375637,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amoxicillin,DB01060
,170512,DB00996,10007632,41,38912,15,22410,0.164369274,1.574155853,0.852845694,3.062368659,0.303253061,DB0099610007632_,1.193187638,0.453719162,NA,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,gabapentin,DB00996
,170514,DB00370,10025482,115,4426,60,3603,0.005559008,1.560183367,1.128406393,2.175892185,0.022269073,DB0037010025482_,3.804556417,0.444803357,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,170515,DB08931,10042609,45,6532,25,2421,0.106570764,0.667179006,0.399467917,1.13798996,0.220968095,DB0893110042609_,1.509736953,-0.404696895,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,riociguat,DB08931
,170526,DB01075,10035226,57,19891,52,11045,0.011951338,0.608650458,0.41027822,0.904774524,0.04101887,DB0107510035226_,3.193723063,-0.496511137,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,diphenhydramine,DB01075
,170543,DB01033,10009887,17,1165,45,1259,0.00121127,0.408423708,0.217861003,0.732535238,0.00645086,DB0103310009887_,5.043541769,-0.895450145,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,mercaptopurine,DB01033
,170545,DB00635,10025310,21,33032,33,23761,0.005360817,0.457759025,0.251629361,0.815364594,0.021623429,DB0063510025310_,3.833977871,-0.78141238,NA,10025310,Lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,170565,DB00341,10074903,54,11351,13,5055,0.046356497,1.849793459,0.995144196,3.698308038,0.118207269,DB0034110074903_,2.135315681,0.615073989,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,170570,DB00047,10057362,68,9217,60,8458,0.85930883,1.0400127,0.723120944,1.499019854,0.933344323,DB0004710057362_,0.068981097,0.039232925,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,170574,DB01224,10012267,36,8072,40,5877,0.079988085,0.655298132,0.405310761,1.055990823,0.178396065,DB0122410012267_,1.723749115,-0.422664983,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,170597,DB01590,10016322,42,4696,29,2838,0.623126166,0.875276218,0.531157048,1.46053051,0.763263492,DB0159010016322_,0.27015197,-0.133215765,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,170603,DB00327,10014625,51,6087,26,4236,0.203316002,1.36501244,0.833810181,2.284676715,0.353029536,DB0032710014625_,1.041203554,0.311163542,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,170613,DB00563,10000269,40,46606,15,15333,0.641224703,0.877330828,0.474016553,1.710170955,0.777964058,DB0056310000269_,0.251074953,-0.130871131,NA,10000269,Abscess,10021881,Infections and infestations,Infec,methotrexate,DB00563
,170623,DB00047,10035528,41,9244,53,8465,0.098783525,0.708412457,0.458929495,1.086610614,0.208984261,DB0004710035528_,1.565496336,-0.344728788,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,insulin glargine,DB00047
,170642,DB01104,10058080,47,15416,23,7263,0.898167905,0.962767962,0.572486604,1.662548984,0.956353692,DB0110410058080_,0.044627464,-0.037942849,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,sertraline,DB01104
,170657,DB00448,10016322,74,5071,21,3103,0.001311706,2.156074795,1.310046131,3.694323815,0.00688325,DB0044810016322_,4.978664356,0.768289344,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,lansoprazole,DB00448
,170661,DB00448,10043071,30,5115,33,3091,0.018769593,0.549428943,0.322989621,0.931236398,0.058771667,DB0044810043071_,2.834095391,-0.598875826,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,lansoprazole,DB00448
,170666,DB00182,10007515,76,5118,95,2757,6.57601175867602e-08,0.430993504,0.31333045,0.591172136,1.23800988018589e-06,DB0018210007515_,13.6020054,-0.841662262,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,amphetamine,DB00182
,170667,DB00514,10007515,45,2121,35,1501,0.731051185,0.909905111,0.568952918,1.465794035,0.843569972,DB0051410007515_,0.170112426,-0.094414958,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,dextromethorphan,DB00514
,170671,DB01104,10014387,54,15409,35,7251,0.140379366,0.726011562,0.465416849,1.14585248,0.270399504,DB0110410014387_,1.30785477,-0.320189339,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,sertraline,DB01104
,170675,DB00514,10016256,82,2084,41,1495,0.06321235,1.434604273,0.968281287,2.154363509,0.149319857,DB0051410016256_,1.90166458,0.360889043,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dextromethorphan,DB00514
,170677,DB01104,10019196,46,15417,20,7266,0.894967115,1.083979752,0.627997304,1.936018393,0.955976233,DB0110410019196_,0.045022227,0.080639224,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,170678,DB00514,10019211,58,2108,13,1523,4.36871351332021e-05,3.222487692,1.737423328,6.434640069,0.000394141,DB0051410019211_,7.838801007,1.170153636,female,10019211,Headache,10029205,Nervous system disorders,Nerv,dextromethorphan,DB00514
,170679,DB00182,10024855,44,5150,21,2831,0.696421627,1.151736064,0.66881527,2.043598695,0.817353208,DB0018210024855_,0.201683954,0.141270425,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,170681,DB00182,10037660,45,5149,34,2818,0.157886517,0.724412045,0.452596057,1.169108219,0.2946407,DB0018210037660_,1.221998633,-0.322394925,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,170689,DB00514,10040108,31,2135,27,1509,0.424641473,0.811553645,0.466560242,1.419674632,0.593423421,DB0051410040108_,0.521847102,-0.208804788,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,dextromethorphan,DB00514
,170696,DB00451,10048865,154,47117,55,15364,0.573401441,0.913020453,0.66661325,1.266655242,0.723293325,DB0045110048865_,0.323940434,-0.090996997,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,levothyroxine,DB00451
,170698,DB00904,10048865,41,23028,41,14415,0.040262951,0.626007683,0.395775107,0.990099892,0.106170913,DB0090410048865_,2.242705097,-0.468392635,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,ondansetron,DB00904
,170700,DB01136,10048865,37,9847,37,11078,0.641900689,1.125005477,0.693070509,1.826086459,0.778454748,DB0113610048865_,0.250444416,0.117787904,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,carvedilol,DB01136
,170707,DB00904,10057668,66,23003,28,14428,0.089563817,1.478437849,0.936388545,2.390906524,0.194520548,DB0090410057668_,1.637217478,0.390986023,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,170722,DB01098,10022061,47,8102,25,7184,0.043693182,1.666926341,1.004179561,2.829233298,0.112961079,DB0109810022061_,2.180711957,0.510981416,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,170728,DB00722,10022081,63,25340,34,25998,0.002213009,1.901020379,1.233115722,2.976800435,0.010565605,DB0072210022081_,4.550151393,0.642390784,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,170770,DB01097,10053425,70,6195,6,1497,0.008238312,2.818974379,1.228797222,7.957634233,0.030495889,DB0109710053425_,3.490163399,1.036373123,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,170777,DB00722,10017822,31,25372,30,26002,0.898239162,1.059015398,0.61987418,1.811591588,0.956353692,DB0072210017822_,0.044627464,0.057339607,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,170781,DB00531,10012818,38,7214,66,6450,0.001064279,0.514811221,0.335498989,0.780008457,0.005797838,DB0053110012818_,5.150270144,-0.663955007,NA,10012818,Diffuse large B-cell lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyclophosphamide,DB00531
,170784,DB00635,10012818,57,32996,43,23751,0.839584651,0.954203219,0.630776703,1.452859418,0.917802954,DB0063510012818_,0.085772558,-0.046878612,NA,10012818,Diffuse large B-cell lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,170798,DB01190,10013573,85,4849,37,2248,0.844411266,1.065018701,0.713344172,1.617588581,0.921373327,DB0119010013573_,0.081889975,0.062992359,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,clindamycin,DB01190
,170803,DB00331,10018838,42,24904,30,20722,0.555303971,1.164900897,0.711695867,1.92825237,0.708749529,DB0033110018838_,0.344253088,0.152636016,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,metformin,DB00331
,170812,DB09020,10025482,54,1900,31,1573,0.122303129,1.441991407,0.905462455,2.332779729,0.244727294,DB0902010025482_,1.407610772,0.36602508,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,bisacodyl,DB09020
,170814,DB00046,10027175,59,5400,26,4666,0.004253143,1.960620853,1.214327517,3.246317012,0.017961738,DB0004610027175_,4.019511471,0.673261185,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,insulin lispro,DB00046
,170824,DB00588,10038153,66,16458,28,8440,0.445599915,1.208755908,0.765353188,1.955495601,0.613465694,DB0058810038153_,0.488630935,0.189591655,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,170828,DB01075,10038153,54,19894,37,11060,0.326243356,0.811399552,0.523930007,1.269011642,0.494738742,DB0107510038153_,0.703725449,-0.208994681,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,diphenhydramine,DB01075
,170831,DB00046,10047942,35,5424,21,4671,0.226468313,1.435234225,0.8112336,2.598628325,0.381474549,DB0004610047942_,0.963711144,0.361328059,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,insulin lispro,DB00046
,170832,DB00047,10047942,50,9235,48,8470,0.839875105,0.955363252,0.629192367,1.452096736,0.918021297,DB0004710047942_,0.08553469,-0.045663642,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,insulin glargine,DB00047
,170833,DB00207,10047942,78,9002,51,5404,0.648542852,0.918129452,0.635812469,1.335856273,0.783461584,DB0020710047942_,0.24403325,-0.085416883,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,azithromycin,DB00207
,170834,DB00586,10047942,63,7046,12,2793,0.0197381,2.080945896,1.109692381,4.246159256,0.06115949,DB0058610047942_,2.794270242,0.732822548,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,diclofenac,DB00586
,170836,DB00641,10047942,180,13944,129,12346,0.075365134,1.235428937,0.978611961,1.563193256,0.170435563,DB0064110047942_,1.769397986,0.211418227,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,simvastatin,DB00641
,170841,DB00158,10060800,71,16744,12,8092,0.000236225,2.859293865,1.538142233,5.795924604,0.001655338,DB0015810060800_,6.403750054,1.050574694,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,folic acid,DB00158
,170842,DB00425,10060800,74,12621,19,7465,0.000758768,2.303550005,1.375383873,4.042971179,0.004376133,DB0042510060800_,5.431589853,0.834451413,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,zolpidem,DB00425
,170851,DB11089,10060800,44,10131,16,8391,0.003972043,2.277540694,1.258932817,4.327380737,0.016982664,DB1108910060800_,4.075562206,0.823096218,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,docusate,DB11089
,170873,DB01075,10016807,61,19887,17,11080,0.009147387,1.999136208,1.151905906,3.653017299,0.033150292,DB0107510016807_,3.406703767,0.692715191,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,diphenhydramine,DB01075
,170882,DB00956,10023232,47,5767,25,3442,0.714323129,1.122073274,0.675330119,1.906105256,0.830630337,DB0095610023232_,0.185570425,0.115178111,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocodone,DB00956
,170883,DB00341,10035528,89,11316,37,5031,0.772081173,1.069418221,0.720035535,1.616992435,0.875238437,DB0034110035528_,0.13325893,0.067114782,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,cetirizine,DB00341
,170884,DB01050,10035528,84,18024,56,9315,0.152588939,0.775246114,0.545768409,1.108468809,0.287590968,DB0105010035528_,1.246216059,-0.254574733,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,ibuprofen,DB01050
,170885,DB00874,10047899,50,3285,16,1960,0.029269336,1.864335361,1.040712435,3.51745588,0.083090887,DB0087410047899_,2.48782025,0.622904615,NA,10047899,Weight increased,10022891,Investigations,Inv,guaifenesin,DB00874
,170886,DB01075,10047899,199,19749,85,11012,0.040195023,1.305433838,1.006553189,1.705230075,0.106070661,DB0107510047899_,2.243649795,0.266535429,NA,10047899,Weight increased,10022891,Investigations,Inv,diphenhydramine,DB01075
,170900,DB00213,10001949,78,18817,35,13386,0.027395222,1.585332358,1.050414563,2.436106074,0.078866288,DB0021310001949_,2.540001416,0.460794075,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,170902,DB01202,10001949,51,6663,36,5682,0.450102765,1.208070344,0.771951171,1.908421909,0.617771979,DB0120210001949_,0.481635856,0.189024329,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,170906,DB01068,10013990,49,13714,16,6824,0.14903304,1.523851777,0.851118945,2.873013686,0.282634262,DB0106810013990_,1.263601578,0.421241194,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,clonazepam,DB01068
,170911,DB01068,10018100,37,13726,27,6813,0.143305283,0.680188162,0.402749263,1.162672298,0.274466581,DB0106810018100_,1.292925772,-0.38538581,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,170937,DB01115,10037844,78,3522,43,2225,0.509984359,1.14596082,0.776676342,1.710492419,0.670531919,DB0111510037844_,0.399683972,0.136243429,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,nifedipine,DB01115
,170941,DB01073,10043071,27,1038,33,1617,0.352970829,1.274433102,0.732405527,2.200060858,0.522724561,DB0107310043071_,0.648700605,0.242501454,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,fludarabine,DB01073
,170943,DB00169,10021688,76,38615,23,18152,0.066687867,1.553284768,0.963028727,2.596602899,0.155377439,DB0016910021688_,1.861898032,0.440371894,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,170954,DB01267,10001497,26,2826,52,3663,0.08424498,0.648131411,0.387430406,1.060082472,0.185477548,DB0126710001497_,1.684821439,-0.433661809,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,170960,DB00907,10033295,43,1095,78,1733,0.505793057,0.872497099,0.582181005,1.292851874,0.666671873,DB0090710033295_,0.405457298,-0.13639595,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,cocaine,DB00907
,170972,DB05679,10060933,36,6895,18,4891,0.268337317,1.418667589,0.783709896,2.656819396,0.430839223,DB0567910060933_,0.842020291,0.349718113,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,170988,DB06674,10009900,34,4472,25,1465,0.003499253,0.445592843,0.257169078,0.78189304,0.015324538,DB0667410009900_,4.178299936,-0.808349653,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,golimumab,DB06674
,170990,DB00370,10011224,65,4476,35,3628,0.05453831,1.505222263,0.980721494,2.345351285,0.133526405,DB0037010011224_,2.013456029,0.40894057,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mirtazapine,DB00370
,171002,DB00540,10035664,65,2418,41,1050,0.068961678,0.688507064,0.455364682,1.051479641,0.159445636,DB0054010035664_,1.836052258,-0.373229701,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,nortriptyline,DB00540
,171004,DB00316,10041807,38,65436,15,36938,0.256008869,1.43003763,0.768401656,2.798888961,0.416781148,DB0031610041807_,0.875194019,0.357700759,NA,10041807,Sputum discoloured,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,171031,DB00455,10047942,144,9257,69,5049,0.426808848,1.138287646,0.846672127,1.542815589,0.595502446,DB0045510047942_,0.518349783,0.129525068,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,loratadine,DB00455
,171032,DB00512,10047942,50,4687,44,5054,0.351392175,1.225314523,0.799015263,1.884847401,0.521120701,DB0051210047942_,0.651773592,0.203197564,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,vancomycin,DB00512
,171061,DB00924,10003285,55,10107,17,4234,0.302033907,1.35524829,0.773817403,2.493820185,0.468347664,DB0092410003285_,0.758544387,0.303984677,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,171064,DB00820,10005557,28,11887,30,5786,0.003021606,0.454314584,0.261256165,0.787758931,0.013593993,DB0082010005557_,4.298127241,-0.788965404,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,tadalafil,DB00820
,171065,DB00091,10006451,64,5446,9,2661,8.22689314825592e-05,3.474136346,1.716879604,7.954139403,0.000675129,DB0009110006451_,7.300606461,1.245345915,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,cyclosporine,DB00091
,171067,DB00572,10006451,35,2867,17,2109,0.203690051,1.514373843,0.823340521,2.890849176,0.353492208,DB0057210006451_,1.039893835,0.415002048,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,atropine,DB00572
,171072,DB00626,10012735,40,827,17,429,0.568673386,1.220350421,0.667028521,2.324507332,0.719688964,DB0062610012735_,0.328936154,0.199138048,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,bacitracin,DB00626
,171076,DB00421,10013781,51,8852,17,5235,0.043527452,1.774108004,1.006429441,3.280485908,0.112687786,DB0042110013781_,2.183134242,0.573297764,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,171092,DB00421,10017944,49,8854,18,5234,0.098773063,1.609177567,0.919687046,2.938371712,0.208978949,DB0042110017944_,1.565521755,0.475723221,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,171097,DB00820,10017944,90,11825,41,5775,0.779535504,1.072030885,0.732103058,1.59342108,0.87996954,DB0082010017944_,0.127867986,0.069554873,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,171102,DB00421,10037153,62,8841,30,5222,0.388776231,1.220632544,0.776176628,1.95829904,0.558658607,DB0042110037153_,0.582216714,0.199369203,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,spironolactone,DB00421
,171103,DB00455,10037153,107,9294,39,5079,0.029626991,1.499281921,1.028379013,2.226314105,0.083880381,DB0045510037153_,2.478363528,0.404986274,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,loratadine,DB00455
,171104,DB00480,10037153,39,67389,38,67624,0.909775283,1.029901094,0.641647969,1.654521738,0.959437782,DB0048010037153_,0.04140781,0.029462773,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,171110,DB00950,10037153,64,4654,18,2038,0.115561637,1.55689541,0.908489103,2.798935338,0.234540778,DB0095010037153_,1.450125812,0.442693716,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,fexofenadine,DB00950
,171111,DB01013,10037153,88,929,47,560,0.577498486,1.12859315,0.770232091,1.67062484,0.726502713,DB0101310037153_,0.319513061,0.120971857,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,clobetasol propionate,DB01013
,171119,DB00043,10047899,81,6332,18,2282,0.06645812,1.621755737,0.961737884,2.87926302,0.154979522,DB0004310047899_,1.864462287,0.483509351,NA,10047899,Weight increased,10022891,Investigations,Inv,omalizumab,DB00043
,171126,DB00563,10015090,94,46552,45,15303,0.048434249,0.686683513,0.47619328,1.003181858,0.122142783,DB0056310015090_,2.102564563,-0.375881772,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,171127,DB00563,10042772,83,46563,41,15307,0.036944102,0.66549791,0.45228886,0.993011333,0.099480174,DB0056310042772_,2.307796914,-0.407219782,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,171149,DB00476,10019974,78,17179,30,6147,0.742930012,0.930330353,0.602784638,1.470251143,0.852863708,DB0047610019974_,0.159155524,-0.072215538,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,duloxetine,DB00476
,171154,DB13961,10019974,67,9390,18,6396,0.000218644,2.535244162,1.487199233,4.538446311,0.001553469,DB1396110019974_,6.467264464,0.930289949,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,fish oil,DB13961
,171223,DB09153,10020642,40,7759,31,5668,0.810668006,0.942607833,0.57423992,1.56043831,0.898198349,DB0915310020642_,0.107364356,-0.059104955,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,sodium chloride,DB09153
,171227,DB00421,10047513,68,8835,21,5231,0.008004595,1.91711964,1.159060954,3.29724672,0.029793371,DB0042110047513_,3.513469353,0.650823872,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,spironolactone,DB00421
,171237,DB01234,10012267,39,31586,33,32855,0.41029804,1.229292419,0.753155131,2.017524142,0.579719798,DB0123410012267_,0.545210399,0.206438735,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,171245,DB00399,10038435,62,6930,34,4964,0.252820715,1.306175716,0.84485195,2.050467409,0.413142213,DB0039910038435_,0.883963405,0.267103567,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,zoledronic acid,DB00399
,171252,DB00956,10028411,74,5740,23,3444,0.005786188,1.93030853,1.192388098,3.236642151,0.022998633,DB0095610028411_,3.772320483,0.65767985,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocodone,DB00956
,171308,DB01394,10000081,30,1410,29,1974,0.182934026,1.448090144,0.83569772,2.512694983,0.327582578,DB0139410000081_,1.116015111,0.370245546,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,colchicine,DB01394
,171315,DB01104,10038669,102,15361,44,7242,0.657286315,1.092908877,0.759416709,1.595756834,0.790542601,DB0110410038669_,0.235035733,0.088842836,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,171324,DB00531,10063620,50,7202,58,6458,0.208398477,0.773031125,0.517978705,1.150169772,0.359291223,DB0053110063620_,1.023622015,-0.257435966,NA,10063620,Acute lymphocytic leukaemia recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyclophosphamide,DB00531
,171325,DB00541,10063620,38,3096,57,4240,0.753957635,0.912996644,0.58756316,1.404624387,0.861653981,DB0054110063620_,0.148901503,-0.091023074,NA,10063620,Acute lymphocytic leukaemia recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,vincristine,DB00541
,171326,DB00563,10063620,32,46614,53,15295,2.43144260599299e-13,0.198140689,0.123583874,0.313123,1.18903197950746e-11,DB0056310063620_,25.15529651,-1.618777949,male,10063620,Acute lymphocytic leukaemia recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,methotrexate,DB00563
,171330,DB00987,10063620,26,2078,42,2886,0.621044282,0.859798689,0.504349759,1.440583865,0.761476336,DB0098710063620_,0.272496182,-0.151057,NA,10063620,Acute lymphocytic leukaemia recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cytarabine,DB00987
,171332,DB01234,10063620,37,31588,41,32847,0.821222648,0.93838554,0.584925969,1.500867782,0.904725148,DB0123410063620_,0.100124085,-0.063594391,NA,10063620,Acute lymphocytic leukaemia recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,171336,DB08895,10037855,41,28073,13,6633,0.384985225,0.74518822,0.3911738,1.516615482,0.555077295,DB0889510037855_,0.588647904,-0.294118448,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,171345,DB00030,10003549,50,2156,40,1781,0.91501807,1.032580164,0.664276546,1.614214262,0.961992279,DB0003010003549_,0.038748855,0.032060683,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,insulin human,DB00030
,171386,DB00678,10042674,109,15490,61,10663,0.2105724,1.230037123,0.890111619,1.713321813,0.361864308,DB0067810042674_,1.016485977,0.20704435,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,171388,DB00331,10043528,39,24907,16,20736,0.014810532,2.02924444,1.107820431,3.891162895,0.048823583,DB0033110043528_,3.019541824,0.707663527,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,171413,DB00813,10042674,55,10517,29,10139,0.008437561,1.828325109,1.144728127,2.976231493,0.031077041,DB0081310042674_,3.471285968,0.603400307,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,171415,DB01076,10048334,99,25648,69,25514,0.024856121,1.427270288,1.038510112,1.971050244,0.073179114,DB0107610048334_,2.614845228,0.355763731,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,171431,DB00641,10019196,39,14085,27,12448,0.38760493,1.276553432,0.761286788,2.169827023,0.557630912,DB0064110019196_,0.584057984,0.244163815,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,171433,DB00334,10012735,80,2769,40,2772,0.000295678,2.001917643,1.347824,3.015579898,0.00199407,DB0033410012735_,6.217577748,0.694105542,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,olanzapine,DB00334
,171473,DB08820,10049414,53,4348,38,3507,0.597818336,1.124921628,0.725886858,1.758314898,0.742861971,DB0882010049414_,0.297245024,0.117713369,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,ivacaftor,DB08820
,171474,DB08820,10061922,100,4301,78,3467,0.878868814,1.033451322,0.758194104,1.412921184,0.949059889,DB0882010061922_,0.052283375,0.032903999,NA,10061922,Pulmonary function test decreased,10022891,Investigations,Inv,ivacaftor,DB08820
,171485,DB00641,10005191,60,14064,48,12427,0.630172243,1.104473841,0.742475879,1.65085853,0.769134352,DB0064110005191_,0.262489614,0.099369059,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,171486,DB01015,10005191,46,9841,41,9340,0.830027582,1.06485448,0.682952662,1.665326154,0.910798822,DB0101510005191_,0.093433238,0.062838151,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,171492,DB00264,10037855,55,29552,43,24849,0.761327602,1.075536491,0.708305755,1.642601962,0.867650712,DB0026410037855_,0.141966051,0.072819599,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,171494,DB00641,10040844,47,14077,44,12431,0.833561423,0.943253644,0.611389598,1.457826879,0.913570529,DB0064110040844_,0.090394699,-0.058420056,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,simvastatin,DB00641
,171495,DB01015,10040844,39,9848,41,9340,0.655748142,0.902156949,0.566206507,1.435344699,0.789387371,DB0101510040844_,0.236498114,-0.102966773,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,171501,DB01015,10044223,25,9862,33,9348,0.237042468,0.718107514,0.409054217,1.24600556,0.394383092,DB0101510044223_,0.930432527,-0.33113598,NA,10044223,Toxic epidermal necrolysis,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,171527,DB00814,10013911,46,8241,18,3397,1,1.053413615,0.598067384,1.933283152,1,DB0081410013911_,0,0.052035953,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,171537,DB01075,10037153,58,19890,32,11065,1,1.008311169,0.643573642,1.60573432,1,DB0107510037153_,0,0.008276821,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,171538,DB00065,10037162,67,9397,35,4922,1,1.002672409,0.65564657,1.55745588,1,DB0006510037162_,0,0.002668844,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,infliximab,DB00065
,171540,DB01068,10037162,44,13719,16,6824,0.336998051,1.367884818,0.756075811,2.598942949,0.50614215,DB0106810037162_,0.680937719,0.313265618,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,171547,DB00316,10008611,57,65417,13,36940,0.00174009,2.475903666,1.338816542,4.931106538,0.008665831,DB0031610008611_,4.748367418,0.906605447,NA,10008611,Cholecystectomy,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,171554,DB00688,10002855,39,6451,22,5356,0.157448249,1.471772759,0.850106889,2.609636392,0.294117492,DB0068810002855_,1.22377596,0.386467633,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,mycophenolate mofetil,DB00688
,171555,DB08912,10047571,53,1277,41,1493,0.058002484,1.511100285,0.978978778,2.346916327,0.13970697,DB0891210047571_,1.968208123,0.412838051,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,dabrafenib,DB08912
,171564,DB00480,10013036,44,67384,39,67623,0.584926806,1.132205005,0.718793808,1.789431673,0.732568728,DB0048010013036_,0.311198116,0.124167063,NA,10013036,Diplopia,10015919,Eye disorders,Eye,lenalidomide,DB00480
,171570,DB00820,10059168,106,11809,28,5788,0.002980734,1.85545202,1.21213498,2.927282268,0.013436561,DB0082010059168_,4.309775882,0.618128343,NA,10059168,Oxygen consumption increased,10022891,Investigations,Inv,tadalafil,DB00820
,171571,DB06186,10028813,96,2113,121,3525,0.045807614,1.323471571,0.99613565,1.754554046,0.117108704,DB0618610028813_,2.144652679,0.280258262,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ipilimumab,DB06186
,171573,DB00654,10020751,125,3691,47,2551,0.000367046,1.837970227,1.299017786,2.638585023,0.002387479,DB0065410020751_,6.037517442,0.608661825,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,latanoprost,DB00654
,171579,DB06228,10007554,52,15860,52,16024,1,1.010340994,0.674047566,1.514390131,1,DB0622810007554_,0,0.010287892,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,171588,DB00370,10061818,74,4467,39,3624,0.035615188,1.539275358,1.028048976,2.336599653,0.096723867,DB0037010061818_,2.335895094,0.431311759,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,mirtazapine,DB00370
,171589,DB00888,10061818,28,649,47,718,0.096428783,0.659272154,0.392573011,1.089204285,0.205401725,DB0088810061818_,1.582787586,-0.41661885,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,mechlorethamine,DB00888
,171591,DB05676,10033664,53,47076,19,25310,0.13878127,1.499728048,0.873145831,2.683210355,0.26806773,DB0567610033664_,1.316515605,0.40528379,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,171616,DB01261,10016322,47,3734,36,3267,0.581300664,1.142251927,0.722314459,1.819919332,0.72966204,DB0126110016322_,0.31517381,0.133001689,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,171624,DB00669,10022086,162,6215,35,1062,0.220447335,0.790943295,0.542535554,1.181793296,0.374004919,DB0066910022086_,0.983486329,-0.234529001,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,171679,DB01202,10061623,32,6682,26,5692,0.895573118,1.048426191,0.604540421,1.833964284,0.95615204,DB0120210061623_,0.044838341,0.047290174,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,171681,DB08932,10013990,67,19376,24,6573,0.80967923,0.947026268,0.585678748,1.580296382,0.897443276,DB0893210013990_,0.108205363,-0.054428448,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,macitentan,DB08932
,171684,DB08895,10003553,139,27975,11,6635,6.64478484677044e-05,2.997004422,1.622865797,6.147083523,0.000561331,DB0889510003553_,7.485199642,1.097613264,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,171685,DB08895,10009033,83,28031,21,6625,0.802602018,0.934118498,0.572700498,1.589174999,0.893233721,DB0889510009033_,0.112907006,-0.068151977,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,171702,DB00313,10053762,57,1182,50,1467,0.091625984,1.414677127,0.942759152,2.128615965,0.197854918,DB0031310053762_,1.620221255,0.346901326,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,valproic acid,DB00313
,171703,DB00319,10053762,30,1362,51,1802,0.307311743,0.778326783,0.475860416,1.253118881,0.47446045,DB0031910053762_,0.745577015,-0.250608813,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,piperacillin,DB00319
,171704,DB00368,10053762,34,626,35,763,0.536352132,1.183884339,0.707328983,1.979634998,0.692660528,DB0036810053762_,0.367215259,0.168800845,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,norepinephrine,DB00368
,171706,DB00683,10053762,68,1516,62,1576,0.475061894,1.140134762,0.790061177,1.647846697,0.640654758,DB0068310053762_,0.445264566,0.131146468,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,midazolam,DB00683
,171707,DB00787,10053762,239,16761,219,17029,0.279480497,1.108770154,0.917972122,1.339775106,0.443313573,DB0078710053762_,0.81347792,0.103251432,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,171708,DB00818,10053762,47,1373,57,1620,0.920527009,0.972903241,0.642260529,1.467653176,0.964812755,DB0081810053762_,0.035821232,-0.027470646,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,propofol,DB00818
,171709,DB06218,10053762,174,1520,164,1272,0.325914568,0.887904015,0.703779163,1.120519907,0.494425557,DB0621810053762_,0.704358681,-0.118891633,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lacosamide,DB06218
,171737,DB00319,10073508,19,1373,45,1808,0.040432145,0.556090751,0.305693645,0.975330089,0.106520892,DB0031910073508_,2.239414148,-0.586823778,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,piperacillin,DB00319
,171742,DB00959,10073508,33,8045,19,4983,0.886704623,1.075787958,0.593299703,2.004681045,0.952921521,DB0095910073508_,0.048222728,0.073053377,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,methylprednisolone,DB00959
,171790,DB00264,10012267,40,29567,42,24850,0.320220628,0.800448602,0.50574927,1.265108892,0.488465845,DB0026410012267_,0.716485729,-0.222582956,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,171802,DB01076,10043528,31,25716,22,25561,0.271561059,1.400582914,0.784973932,2.539609101,0.434382014,DB0107610043528_,0.833830917,0.336888517,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,171815,DB00515,10035528,49,1821,37,2114,0.062611321,1.537227434,0.97780595,2.435138302,0.148318185,DB0051510035528_,1.908395413,0.429980426,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,cisplatin,DB00515
,171819,DB00115,10008469,116,18309,46,10426,0.040245998,1.435978822,1.011348371,2.068914194,0.106142182,DB0011510008469_,2.242975748,0.361846723,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,171823,DB00641,10020919,46,14078,30,12445,0.206849779,1.355453764,0.836889495,2.225422536,0.357500506,DB0064110020919_,1.028618502,0.304136279,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,simvastatin,DB00641
,171824,DB01104,10020919,50,15413,18,7268,0.364004279,1.309794579,0.750350386,2.387425039,0.533607677,DB0110410020919_,0.628094396,0.269870315,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,sertraline,DB01104
,171825,DB01104,10035598,55,15408,34,7252,0.212101235,0.761350221,0.48717455,1.205489942,0.363884927,DB0110410035598_,1.010917597,-0.272661815,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,171864,DB01104,10061422,64,15399,52,7234,0.003754783,0.578184429,0.394284992,0.851348369,0.016208652,DB0110410061422_,4.12221013,-0.547862381,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,171873,DB00443,10011906,24,2122,32,1158,0.001067995,0.409398053,0.229554509,0.721087272,0.005813865,DB0044310011906_,5.147509767,-0.893067362,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,betamethasone,DB00443
,171877,DB01225,10022595,36,5008,46,4594,0.149389765,0.717941104,0.450025711,1.137334891,0.283136749,DB0122510022595_,1.261825284,-0.331367741,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,enoxaparin,DB01225
,171981,DB00404,10039073,124,19768,20,9842,1.75106967508794e-07,3.086732265,1.913788954,5.231513267,3.01124412232166e-06,DB0040410039073_,12.71315723,1.127113012,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,171982,DB00736,10039073,101,10490,18,5535,3.75529586302531e-06,2.960511875,1.77932828,5.201927012,4.59320389760913e-05,DB0073610039073_,9.988347667,1.085362184,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,171983,DB01098,10039073,43,8106,24,7185,0.08517719,1.588046439,0.94124528,2.738849697,0.187072395,DB0109810039073_,1.676259595,0.462504606,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,171984,DB01104,10039073,88,15375,19,7267,0.001186922,2.189053283,1.320992948,3.810531501,0.006349497,DB0110410039073_,5.059379729,0.783469159,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,171985,DB06674,10039073,174,4332,28,1462,0.000128063,2.097088482,1.394204073,3.261936744,0.000984684,DB0667410039073_,6.923189364,0.740549945,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,golimumab,DB06674
,171988,DB00404,10043414,63,19829,17,9845,0.023646499,1.839918184,1.062715961,3.355976555,0.07040646,DB0040410043414_,2.653470256,0.609721105,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,171989,DB01373,10043414,39,22681,12,7369,1,1.055890296,0.541324548,2.216434546,1,DB0137310043414_,0,0.054384293,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,171990,DB06674,10043414,59,4447,22,1468,0.606372054,0.885327755,0.532209942,1.522965313,0.749333538,DB0667410043414_,0.288571083,-0.121797358,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,golimumab,DB06674
,171997,DB00958,10028116,53,4541,40,2545,0.158949073,0.742649269,0.481824422,1.152565448,0.296100382,DB0095810028116_,1.217056755,-0.297531392,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,172001,DB09068,10010774,62,2333,16,970,0.101167335,1.61091849,0.912704006,3.006513795,0.21256462,DB0906810010774_,1.548509241,0.476804507,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,vortioxetine,DB09068
,172005,DB00457,10012735,36,643,15,496,0.059228195,1.850402393,0.975092197,3.680988677,0.142028928,DB0045710012735_,1.951724524,0.615403125,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,prazosin,DB00457
,172012,DB00182,10043071,41,5153,26,2826,0.608323688,0.864835528,0.515281403,1.475896841,0.751034851,DB0018210043071_,0.286303222,-0.145215931,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,amphetamine,DB00182
,172044,DB01136,10048334,37,9847,17,11098,0.001601077,2.452885374,1.346051495,4.648056602,0.008104047,DB0113610048334_,4.81539171,0.897265035,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,carvedilol,DB01136
,172048,DB01281,10012735,162,8770,25,1773,0.236130014,1.310006276,0.85317021,2.090697741,0.393362957,DB0128110012735_,0.933022537,0.270031928,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,abatacept,DB01281
,172050,DB01281,10068319,59,8873,17,1781,0.215463445,0.696648439,0.399484248,1.277969849,0.367960021,DB0128110068319_,0.999780985,-0.361474387,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,abatacept,DB01281
,172059,DB00316,10005839,34,65440,34,36919,0.022263576,0.564198332,0.340187198,0.935621409,0.067217791,DB0031610005839_,2.699817321,-0.572349437,NA,10005839,Blood triglycerides increased,10022891,Investigations,Inv,acetaminophen,DB00316
,172082,DB00188,10037377,80,7806,131,8697,0.006756098,0.680410217,0.507750181,0.907031589,0.026053996,DB0018810037377_,3.647584137,-0.385059403,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bortezomib,DB00188
,172105,DB00471,10043882,41,14148,16,5449,1,0.986928773,0.541413671,1.885643953,1,DB0047110043882_,0,-0.013157408,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,montelukast,DB00471
,172116,DB06605,10018838,38,14035,38,12995,0.81835333,0.925920341,0.574418566,1.49245056,0.903059143,DB0660510018838_,0.101967231,-0.076967073,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,apixaban,DB06605
,172117,DB06605,10018884,269,13804,262,12771,0.568725691,0.94986515,0.796912538,1.132386339,0.719737833,DB0660510018884_,0.328868254,-0.051435252,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,apixaban,DB06605
,172121,DB00814,10028372,85,8202,36,3379,0.919969391,0.972714719,0.650010713,1.482274366,0.964555064,DB0081410028372_,0.036088358,-0.027664437,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,172122,DB00814,10029331,73,8214,42,3373,0.098424402,0.71375404,0.480685219,1.071981323,0.208526612,DB0081410029331_,1.567688612,-0.337216858,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,172131,DB00641,10028641,25,14099,30,12445,0.28050403,0.735585354,0.41457035,1.294656946,0.444361734,DB0064110028641_,0.811116333,-0.307088697,NA,10028641,Myopathy,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,172148,DB01062,10020751,51,4435,8,1737,0.012579313,2.496433036,1.172870998,6.104390438,0.042751946,DB0106210020751_,3.152340563,0.914862927,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,oxybutynin,DB01062
,172149,DB01062,10037844,103,4383,29,1716,0.141182321,1.390424994,0.909342038,2.186790114,0.271528303,DB0106210037844_,1.303688898,0.329609451,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,oxybutynin,DB01062
,172151,DB00476,10020765,56,17201,34,6143,0.016428353,0.588230143,0.377033551,0.930094178,0.052909301,DB0047610020765_,2.93917613,-0.530637007,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,172153,DB00695,10020765,66,27983,40,20488,0.376411519,1.208053944,0.803239558,1.837424755,0.546251306,DB0069510020765_,0.604676141,0.189010754,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,172165,DB01050,10042128,85,18023,24,9347,0.008162128,1.836724762,1.155161315,3.02424885,0.030282102,DB0105010042128_,3.497198444,0.607983965,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,172198,DB00295,10013663,78,14585,86,9516,0.00096397,0.591790631,0.429443424,0.814453144,0.005346121,DB0029510013663_,5.231384039,-0.52460237,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,morphine,DB00295
,172199,DB08910,10007882,55,16689,77,17411,0.098055212,0.745195669,0.517046108,1.067793417,0.207940143,DB0891010007882_,1.570505013,-0.294108452,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,172200,DB00246,10070863,71,1003,27,674,0.014176986,1.766533559,1.106163494,2.89474175,0.047071568,DB0024610070863_,3.056086118,0.569019185,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,ziprasidone,DB00246
,172220,DB00051,10000060,95,25636,38,11382,0.638418082,1.109956615,0.753937196,1.66357354,0.775615044,DB0005110000060_,0.254098959,0.104320929,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,172223,DB00425,10013496,63,12632,16,7468,0.001523494,2.327748641,1.327307899,4.321125331,0.007791621,DB0042510013496_,4.854706324,0.844901552,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,172265,DB00003,10000081,39,2959,25,2568,0.258147293,1.353787964,0.796381356,2.340964089,0.419071833,DB0000310000081_,0.869712934,0.302906562,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,dornase alfa,DB00003
,172287,DB00005,10014561,36,128046,21,42398,0.045407455,0.567629783,0.322481862,1.023461237,0.116357296,DB0000510014561_,2.151089682,-0.566285864,NA,10014561,Emphysema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,172292,DB00888,10010264,25,652,30,735,0.890768266,0.9394384,0.523873028,1.6716015,0.954680373,DB0088810010264_,0.046378682,-0.062473029,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,mechlorethamine,DB00888
,172296,DB00888,10040829,53,624,31,734,0.002326747,2.01011692,1.249066082,3.283206678,0.011005675,DB0088810040829_,4.509344239,0.698192889,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,mechlorethamine,DB00888
,172297,DB01104,10040829,56,15407,16,7270,0.077321691,1.651488961,0.933238699,3.086703127,0.173806016,DB0110410040829_,1.749815454,0.501677281,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,sertraline,DB01104
,172306,DB00476,10042609,93,17164,24,6153,0.171382988,1.389071877,0.878126525,2.278061279,0.312746587,DB0047610042609_,1.162362043,0.32863581,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,duloxetine,DB00476
,172311,DB01104,10042609,59,15404,12,7274,0.004950674,2.32165153,1.233836479,4.748022895,0.0203167,DB0110410042609_,3.896312081,0.842278799,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,sertraline,DB01104
,172321,DB00678,10067482,53,15546,37,10687,1,0.984713123,0.63451007,1.542632003,1,DB0067810067482_,0,-0.015404926,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,172322,DB00787,10033645,35,16965,21,17227,0.06100939,1.692369245,0.957650512,3.061048861,0.145309154,DB0078710033645_,1.928891713,0.526129467,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,172325,DB00193,10012373,45,19275,8,8694,0.011024546,2.537089323,1.182977618,6.234418593,0.038470654,DB0019310012373_,3.257859561,0.931017488,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,172326,DB00230,10012373,48,19626,11,8640,0.047917135,1.920975389,0.983165144,4.103913564,0.121199181,DB0023010012373_,2.110319964,0.652833072,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,172327,DB00472,10012373,52,10707,11,4301,0.050787933,1.898875342,0.977639564,4.040328192,0.126476189,DB0047210012373_,2.067701215,0.641261786,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,172332,DB01268,10065154,23,2120,38,3092,0.695244763,0.882763278,0.500554319,1.525326492,0.816560818,DB0126810065154_,0.202653883,-0.124698202,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,sunitinib,DB01268
,172339,DB00451,10015137,49,47222,7,15412,0.042046549,2.284439777,1.029075297,5.979785391,0.109796236,DB0045110015137_,2.209129029,0.82612082,NA,10015137,Eructation,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,172344,DB06655,10015137,38,3650,21,2098,1,1.0400998,0.593308368,1.870766347,1,DB0665510015137_,0,0.03931667,NA,10015137,Eructation,10017947,Gastrointestinal disorders,Gastr,liraglutide,DB06655
,172369,DB09037,10035598,19,2507,31,2804,0.203519512,0.685562191,0.364936434,1.256131416,0.353324552,DB0903710035598_,1.040368234,-0.37751606,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pembrolizumab,DB09037
,172379,DB00126,10037162,42,10129,10,5935,0.008898835,2.46083131,1.213877893,5.503980339,0.032421633,DB0012610037162_,3.428929379,0.900499224,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,172402,DB01076,10048561,21,25726,41,25542,0.010864133,0.508541256,0.285394125,0.880991373,0.038039662,DB0107610048561_,3.269125935,-0.676208934,NA,10048561,Stent placement,10042613,Surgical and medical procedures,Surg,atorvastatin,DB01076
,172431,DB01611,10022611,58,11855,14,2347,0.523735471,0.820212582,0.450919297,1.595099712,0.681847591,DB0161110022611_,0.38294912,-0.198191726,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxychloroquine,DB01611
,172432,DB00227,10035664,85,2382,82,1721,0.078422148,0.748996125,0.542790366,1.034006721,0.175735905,DB0022710035664_,1.73877295,-0.289021469,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,lovastatin,DB00227
,172433,DB00627,10035664,33,1296,54,1545,0.189338673,0.728602375,0.454639374,1.152084228,0.335734715,DB0062710035664_,1.091433968,-0.316627135,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,niacin,DB00627
,172440,DB01156,10037423,37,13585,21,6307,0.480889117,0.8180135,0.466020344,1.47211163,0.645614855,DB0115610037423_,0.437552153,-0.200876439,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,172441,DB01611,10037423,37,11876,13,2348,0.084146873,0.562740101,0.291820922,1.155596293,0.185320533,DB0161110037423_,1.685668342,-0.574937389,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxychloroquine,DB01611
,172446,DB01611,10038695,71,11842,36,2325,1.78360938126525e-05,0.387250992,0.255132477,0.597015567,0.00018049,DB0161110038695_,8.619837421,-0.948682237,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxychloroquine,DB01611
,172475,DB06724,10010774,237,7692,102,3817,0.24205514,1.152978851,0.907262829,1.473762908,0.400265444,DB0672410010774_,0.915627342,0.142348898,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,172502,DB00243,10053762,44,1210,56,1570,0.918700742,1.019479011,0.665874936,1.552377049,0.964070944,DB0024310053762_,0.036590393,0.019291724,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ranolazine,DB00243
,172505,DB09153,10022004,66,7733,27,5672,0.011095379,1.792869761,1.128152961,2.922835146,0.038663933,DB0915310022004_,3.252848076,0.583817554,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,172518,DB00455,10038435,55,9346,38,5080,0.276429405,0.786744994,0.510203272,1.224562205,0.439867235,DB0045510038435_,0.821282337,-0.239851106,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,loratadine,DB00455
,172536,DB00136,10013700,113,1979,76,1606,0.230020485,1.206543265,0.887143652,1.648341597,0.386000721,DB0013610013700_,0.951916042,0.187759465,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,calcitriol,DB00136
,172539,DB09270,10013700,55,3059,15,2353,0.000215895,2.81986779,1.566079918,5.389287812,0.001536427,DB0927010013700_,6.478295637,1.036690001,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,ubidecarenone,DB09270
,172546,DB00722,10015946,57,25346,42,25990,0.108095213,1.391610335,0.917507213,2.125912228,0.223187045,DB0072210015946_,1.499745091,0.330461591,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,lisinopril,DB00722
,172555,DB06724,10016825,39,7890,12,3907,0.179274673,1.609288109,0.824380155,3.379741155,0.322965549,DB0672410016825_,1.13020962,0.475791913,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,calcium carbonate,DB06724
,172557,DB05676,10008190,70,47059,51,25278,0.104792273,0.737301616,0.506478352,1.079701909,0.218184078,DB0567610008190_,1.52241618,-0.304758222,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,172586,DB00175,10022086,67,8064,13,6093,5.78093449173677e-07,3.893795312,2.12741909,7.697245018,8.81391317374135e-06,DB0017510022086_,11.63917904,1.359384341,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,172617,DB00804,10008479,68,2932,18,881,0.699244433,1.135100038,0.663025939,2.039785922,0.81916218,DB0080410008479_,0.199473193,0.126720786,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,dicyclomine,DB00804
,172619,DB00169,10020765,94,38597,62,18113,0.039201755,0.711484669,0.510595886,0.997458757,0.104024848,DB0016910020765_,2.263125482,-0.34040141,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,172620,DB00264,10020765,50,29557,46,24846,0.682500264,0.913711807,0.599638832,1.395068277,0.80796081,DB0026410020765_,0.213241724,-0.090240067,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,172621,DB00316,10020765,120,65354,83,36870,0.164502079,0.815663595,0.61127033,1.092764145,0.30342354,DB0031610020765_,1.192625628,-0.20375327,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,172623,DB00996,10020765,114,38839,59,22366,0.528010504,1.112700646,0.805259189,1.551352005,0.685455295,DB0099610020765_,0.377671997,0.106790075,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,172643,DB01156,10028836,62,13560,20,6308,0.190332386,1.442085701,0.858279503,2.52327075,0.336996853,DB0115610028836_,1.087681688,0.366090469,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,172648,DB00804,10047899,65,2935,12,887,0.132825519,1.636765249,0.871346654,3.345173918,0.25972243,DB0080410047899_,1.348141797,0.492721885,NA,10047899,Weight increased,10022891,Investigations,Inv,dicyclomine,DB00804
,172650,DB00264,10048439,63,29544,7,24885,1.37611925543383e-10,7.580342423,3.47081789,19.61959643,4.38439934897919e-09,DB0026410048439_,19.2452132,2.025558373,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,172654,DB00999,10048439,61,21369,10,12229,5.54034522695532e-05,3.490784638,1.774044196,7.64391212,0.000481972,DB0099910048439_,7.637623613,1.250126536,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,172656,DB00169,10048592,63,38628,25,18150,0.567403232,1.184046155,0.734002316,1.965130077,0.718565872,DB0016910048592_,0.330497898,0.168937518,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,172657,DB00316,10048592,86,65388,64,36889,0.105647809,0.758105679,0.54203476,1.064979491,0.219608751,DB0031610048592_,1.515907719,-0.276932485,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,172675,DB11365,10016288,34,1611,35,1513,0.716703932,0.912364835,0.548960763,1.514786775,0.83251017,DB1136510016288_,0.183309841,-0.091715331,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,sennosides,DB11365
,172677,DB00646,10018884,42,3411,32,1968,0.274200729,0.757314115,0.465078214,1.243830976,0.43734018,DB0064610018884_,0.827043943,-0.277977165,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,nystatin,DB00646
,172678,DB00924,10018884,71,10091,28,4223,0.911966358,1.061170664,0.675277316,1.709953721,0.96056931,DB0092410018884_,0.040229139,0.059372699,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,cyclobenzaprine,DB00924
,172703,DB00188,10028411,35,7851,47,8781,0.439085277,0.832902715,0.521279888,1.319530727,0.607471789,DB0018810028411_,0.498449543,-0.182838432,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,bortezomib,DB00188
,172705,DB00476,10035528,71,17186,39,6138,0.038586788,0.650211579,0.433454881,0.988315452,0.102802933,DB0047610035528_,2.274941398,-0.430457463,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,duloxetine,DB00476
,172708,DB11365,10035528,30,1615,26,1522,0.788619256,1.087343784,0.61839555,1.923721311,0.885530673,DB1136510035528_,0.121568183,0.083737827,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,sennosides,DB11365
,172709,DB00745,10035664,52,2525,21,1062,1,1.041439313,0.612947114,1.829811591,1,DB0074510035664_,0,0.040603711,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,modafinil,DB00745
,172733,DB00019,10068319,40,18972,15,9514,0.391717498,1.337286766,0.722352397,2.607325799,0.561580323,DB0001910068319_,0.577000465,0.290642759,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pegfilgrastim,DB00019
,172734,DB00188,10068319,34,7852,28,8800,0.252067504,1.360857455,0.800143473,2.332093043,0.412167611,DB0018810068319_,0.886325189,0.308114982,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bortezomib,DB00188
,172736,DB00646,10068319,38,3415,13,1987,0.108711139,1.700623949,0.883565936,3.487989556,0.224080323,DB0064610068319_,1.495750708,0.530995213,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nystatin,DB00646
,172741,DB00193,10013952,57,19263,27,8675,0.814172957,0.950731197,0.59106567,1.564566589,0.900338508,DB0019310013952_,0.104984467,-0.05052391,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,172742,DB01068,10013952,49,13714,23,6817,0.900522446,1.058999836,0.63238503,1.822744403,0.956698706,DB0106810013952_,0.044266769,0.057324912,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,172745,DB00996,10015967,71,38882,19,22406,0.00202762,2.153351944,1.282912861,3.785390186,0.0098323,DB0099610015967_,4.622082437,0.767025672,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,gabapentin,DB00996
,172749,DB01068,10074903,153,13610,78,6762,0.888281797,0.974552793,0.735985746,1.299188129,0.953707237,DB0106810074903_,0.047398534,-0.025776587,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,172759,DB00181,10061623,101,9755,50,5821,0.310629441,1.205317067,0.849213793,1.730121776,0.478038341,DB0018110061623_,0.738064339,0.186742658,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,172775,DB01156,10019303,60,13562,20,6308,0.228812274,1.395379611,0.828304248,2.446269658,0.384461957,DB0115610019303_,0.955910436,0.333166501,NA,10019303,Heart rate increased,10022891,Investigations,Inv,bupropion,DB01156
,172780,DB00207,10008190,46,9034,22,5433,0.45156708,1.257461061,0.740253638,2.197335275,0.619215937,DB0020710008190_,0.479301218,0.229094657,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,172798,DB00829,10049848,79,7973,18,4436,0.000269035,2.441729286,1.447431278,4.33622948,0.001845882,DB0082910049848_,6.294797853,0.892706512,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,172805,DB00399,10016322,133,6859,40,4958,3.27591102715232e-07,2.403278204,1.67287186,3.520296742,5.28914750299132e-06,DB0039910016322_,12.14985348,0.876833724,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,172811,DB00169,10030041,80,38611,23,18152,0.034759497,1.635204719,1.017292424,2.726036713,0.094960992,DB0016910030041_,2.354289084,0.491768007,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,172820,DB14500,10002855,95,7714,29,4044,0.0100399,1.717271869,1.120406395,2.705331552,0.035686108,DB1450010002855_,3.332993811,0.540736909,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,potassium,DB14500
,172830,DB00959,10003553,73,8005,15,4987,2.14952987611005e-05,3.031633525,1.720860341,5.696987068,0.000212447,DB0095910003553_,8.45681601,1.109101591,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,172849,DB01373,10021519,102,22618,8,7373,3.66603345530196e-06,4.15619631,2.030093355,9.890976162,4.5025809178603e-05,DB0137310021519_,10.0082747,1.424600308,female,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,172852,DB00656,10013911,32,11981,21,6598,0.566215756,0.839187045,0.468798837,1.532564413,0.717615234,DB0065610013911_,0.33182174,-0.175321659,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,172860,DB01156,10000125,43,13579,12,6316,0.145885071,1.666677204,0.862670832,3.47452806,0.278272068,DB0115610000125_,1.279155982,0.510831946,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,172864,DB00697,10027599,122,5974,10,1796,4.86367940786109e-06,3.667436575,1.922139104,7.85665855,5.77033686461877e-05,DB0069710027599_,9.760195004,1.299492937,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,172869,DB00181,10030095,35,9821,23,5848,0.785850042,0.906140391,0.519920381,1.607928235,0.883799408,DB0018110030095_,0.123525156,-0.098561028,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,172892,DB09072,10021097,38,6433,13,2522,0.756295063,1.145945271,0.595937813,2.348534712,0.863412774,DB0907210021097_,0.1468624,0.136229861,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sodium oxybate,DB09072
,172914,DB00829,10006093,25,8027,33,4421,0.001331229,0.417274757,0.237540732,0.724456305,0.006967798,DB0082910006093_,4.966456054,-0.874010384,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,diazepam,DB00829
,172939,DB00661,10027417,46,3482,10,1585,0.02978521,2.09365472,1.038806863,4.66552448,0.084237598,DB0066110027417_,2.474113926,0.738911209,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,verapamil,DB00661
,172944,DB00999,10042464,39,21391,29,12210,0.312779355,0.767652466,0.462385402,1.287884786,0.480292412,DB0099910042464_,0.73336017,-0.264418167,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,173028,DB00091,10046571,107,5403,15,2655,2.61290866721036e-07,3.504853823,2.027603754,6.493136834,4.31680102562063e-06,DB0009110046571_,12.35299593,1.254148814,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,cyclosporine,DB00091
,173035,DB00710,10000081,45,2361,6,195,0.281554054,0.619583348,0.259034418,1.799527409,0.445492305,DB0071010000081_,0.808575305,-0.478708047,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ibandronate,DB00710
,173048,DB00710,10016256,101,2305,8,193,1,1.057085569,0.506186476,2.553021547,1,DB0071010016256_,0,0.055515658,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ibandronate,DB00710
,173121,DB00736,10007882,66,10525,31,5522,0.668752219,1.116994957,0.717559785,1.773499742,0.798801658,DB0073610007882_,0.224642601,0.110642005,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,173122,DB01137,10007882,45,7727,45,5548,0.133091821,0.718031056,0.463571347,1.112131742,0.260056966,DB0113710007882_,1.346854571,-0.331242458,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,levofloxacin,DB01137
,173126,DB01137,10023232,59,7713,28,5565,0.080524413,1.520275485,0.952700294,2.479814473,0.179287367,DB0113710023232_,1.718765357,0.418891559,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,173127,DB06674,10023232,70,4436,10,1480,0.008779534,2.335307032,1.193437043,5.095665466,0.032078129,DB0667410023232_,3.439580825,0.848143374,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,golimumab,DB06674
,173146,DB00316,10036590,35,65439,32,36921,0.05565198,0.6170726,0.370989165,1.029727161,0.135445583,DB0031610036590_,1.999185318,-0.482768596,NA,10036590,Premature baby,10036585,"Pregnancy, puerperium and perinatal conditions",Preg,acetaminophen,DB00316
,173203,DB00181,10040753,104,9752,31,5840,0.000450668,2.008966932,1.331948772,3.109459781,0.002832573,DB0018110040753_,5.866569718,0.697620626,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,baclofen,DB00181
,173205,DB00295,10040753,86,14577,29,9573,0.001511942,1.947458099,1.264103052,3.080439611,0.007744596,DB0029510040753_,4.860760006,0.666524983,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,morphine,DB00295
,173209,DB00697,10040753,118,5978,8,1798,9.16945712797634e-07,4.435885704,2.173315454,10.53614353,1.32756364973207e-05,DB0069710040753_,11.22958004,1.489727304,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,tizanidine,DB00697
,173210,DB00813,10040753,42,10530,14,10154,0.000397181,2.892979551,1.547575274,5.738747164,0.002547248,DB0081310040753_,5.972741598,1.062286958,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,fentanyl,DB00813
,173211,DB00852,10040753,58,1108,11,460,0.014448368,2.188160843,1.124157392,4.667247966,0.047809573,DB0085210040753_,3.040529389,0.783061393,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,pseudoephedrine,DB00852
,173218,DB09270,10040753,75,3039,23,2345,5.02999010586872e-05,2.515773622,1.553345915,4.220689122,0.00044434,DB0927010040753_,7.718921106,0.922580359,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,ubidecarenone,DB09270
,173223,DB00422,10048393,40,3395,16,2933,0.009917723,2.159490027,1.179767088,4.139889039,0.035316312,DB0042210048393_,3.343410326,0.769872095,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,methylphenidate,DB00422
,173225,DB00564,10048393,52,2552,13,1450,0.00604475,2.272327999,1.215022529,4.564848486,0.023801402,DB0056410048393_,3.738010806,0.820804856,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,carbamazepine,DB00564
,173228,DB00915,10048393,89,1366,24,1027,3.30653277568298e-06,2.78696536,1.744471772,4.609516072,4.1210153631497e-05,DB0091510048393_,10.09682588,1.024953319,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,amantadine,DB00915
,173313,DB00331,10038669,33,24913,40,20712,0.125822721,0.685895752,0.418971325,1.115866813,0.249811181,DB0033110038669_,1.387049923,-0.377029627,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,173361,DB00186,10048334,39,16862,14,9994,0.118063828,1.651045513,0.876453197,3.29394476,0.238286048,DB0018610048334_,1.434283444,0.501408732,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,173364,DB00736,10048334,50,10541,12,5541,0.01094082,2.19016417,1.148898458,4.522203823,0.038249577,DB0073610048334_,3.26362279,0.783976504,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,173367,DB01075,10048334,42,19906,11,11086,0.021794439,2.126364716,1.075352002,4.58171233,0.06615666,DB0107510048334_,2.715729716,0.754413816,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,173389,DB00734,10040108,30,4020,39,4863,0.808957988,0.930527831,0.557156174,1.540082572,0.896971703,DB0073410040108_,0.108730963,-0.072003293,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,173404,DB11089,10011781,59,10116,17,8390,4.18568875275677e-05,2.878164136,1.653701741,5.271711747,0.000379317,DB1108910011781_,7.8771389,1.057152638,female,10011781,Cystitis,10021881,Infections and infestations,Infec,docusate,DB11089
,173405,DB00175,10019974,48,8083,22,6084,0.053448099,1.64217472,0.971092552,2.859997339,0.131457217,DB0017510019974_,2.029073827,0.496021412,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,pravastatin,DB00175
,173406,DB00788,10019974,54,9302,18,5043,0.08270481,1.626373492,0.937754502,2.950031961,0.182910889,DB0078810019974_,1.698756188,0.486352684,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,naproxen,DB00788
,173407,DB01175,10019974,50,10674,20,4872,0.699116569,1.1410748,0.666329447,2.025909977,0.819076564,DB0117510019974_,0.199577715,0.131970625,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,escitalopram,DB01175
,173409,DB11089,10019974,55,10120,31,8376,0.102901228,1.468410551,0.927980779,2.361942643,0.215347036,DB1108910019974_,1.535504431,0.384180558,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,docusate,DB11089
,173410,DB01175,10048393,97,10627,20,4872,0.000612855,2.223410328,1.361829604,3.804672018,0.003664026,DB0117510048393_,5.609192781,0.799042201,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,173417,DB00497,10003246,82,19185,36,16339,0.000798495,1.939813354,1.295086246,2.957527583,0.00456717,DB0049710003246_,5.388861578,0.662591759,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,173419,DB00795,10003246,36,4533,14,1489,0.621657839,0.844717776,0.443135857,1.70027066,0.761926527,DB0079510003246_,0.271905149,-0.168752701,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfasalazine,DB00795
,173422,DB00126,10013952,54,10117,27,5918,0.564563253,1.169932581,0.723257615,1.93392945,0.71634984,DB0012610013952_,0.333586628,0.156946124,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,173426,DB01373,10013952,116,22604,29,7352,0.245148777,1.300986073,0.859054578,2.029550422,0.40393265,DB0137310013952_,0.906507122,0.263122494,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,173428,DB00115,10017918,52,18373,12,10460,0.003796289,2.466956162,1.298826761,5.079722929,0.01635291,DB0011510017918_,4.113349397,0.902985068,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,173436,DB01373,10017918,53,22667,8,7373,0.037062318,2.154767963,1.017313657,5.250469571,0.099716773,DB0137310017918_,2.305421378,0.767683044,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,calcium,DB01373
,173438,DB08895,10017918,76,28038,9,6637,0.051879903,1.998862612,0.998699264,4.540801829,0.128574697,DB0889510017918_,2.051245243,0.692578325,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,173452,DB00126,10039101,64,10107,31,5914,0.455500906,1.208058406,0.774017099,1.921878796,0.622923907,DB0012610039101_,0.473330907,0.189014447,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,173454,DB00381,10039101,147,29213,89,22798,0.065421314,1.288977873,0.983396483,1.697587426,0.153159584,DB0038110039101_,1.876274865,0.253849558,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,173456,DB00829,10039101,39,8013,13,4441,0.14576783,1.662610494,0.867669903,3.398584892,0.278139263,DB0082910039101_,1.279633346,0.508388954,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diazepam,DB00829
,173457,DB01373,10039101,122,22598,40,7341,0.927303701,0.990797989,0.687387957,1.455331882,0.969361391,DB0137310039101_,0.031117784,-0.009244611,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,173460,DB00115,10048908,58,18367,27,10445,0.430104597,1.221563335,0.760747377,2.007771383,0.598575705,DB0011510048908_,0.513202271,0.200131461,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,cyanocobalamin,DB00115
,173461,DB00126,10048908,30,10141,20,5925,0.661375935,0.876404109,0.481018065,1.629715544,0.793457927,DB0012610048908_,0.231354763,-0.131927982,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,ascorbic acid,DB00126
,173464,DB00381,10048908,74,29286,36,22851,0.020705523,1.60387234,1.062656809,2.460472037,0.063516913,DB0038110048908_,2.756449065,0.472420918,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,amlodipine,DB00381
,173470,DB08895,10048908,52,28062,9,6637,0.513648623,1.366497875,0.666844394,3.155858475,0.673648042,DB0889510048908_,0.395047497,0.312251171,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,tofacitinib,DB08895
,173472,DB09539,10003549,22,645,31,649,0.26328401,0.714258904,0.389507498,1.289453261,0.425087236,DB0953910003549_,0.85546087,-0.336509772,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,omega-3-acid ethyl esters,DB09539
,173473,DB09539,10016256,45,622,49,631,0.749658444,0.93173251,0.597888296,1.449051366,0.85816572,DB0953910016256_,0.152958051,-0.070709512,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,omega-3-acid ethyl esters,DB09539
,173492,DB00190,10020100,51,3246,43,4631,0.011478231,1.691949776,1.102457232,2.607712459,0.039760848,DB0019010020100_,3.22487257,0.525881577,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,carbidopa,DB00190
,173513,DB08868,10003674,55,9147,12,2499,0.552448338,1.252159994,0.661252276,2.573335282,0.706330937,DB0886810003674_,0.347671402,0.224870056,NA,10003674,Atrioventricular block first degree,10007541,Cardiac disorders,Card,fingolimod,DB08868
,173538,DB00887,10064911,70,2271,27,1788,0.001282729,2.040840658,1.285797063,3.325015281,0.00675141,DB0088710064911_,4.998003932,0.71336181,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bumetanide,DB00887
,173600,DB08816,10055798,32,1119,45,1857,0.47734221,1.180027723,0.721135448,1.911055272,0.642724176,DB0881610055798_,0.442039611,0.165537932,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,ticagrelor,DB08816
,173611,DB00656,10039020,35,11978,73,6546,1.91581475724356e-11,0.262023015,0.169733291,0.397717988,6.97468017924475e-10,DB0065610039020_,21.08356446,-1.339322936,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,173612,DB00230,10060795,37,19637,14,8637,0.76112519,1.162401844,0.61342802,2.328927368,0.867570495,DB0023010060795_,0.142058508,0.15048842,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,pregabalin,DB00230
,173616,DB08895,10023424,83,28031,6,6640,0.001672838,3.27679749,1.442455209,9.188378614,0.008402549,DB0889510023424_,4.779220204,1.18686657,female,10023424,Kidney infection,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,173619,DB00864,10051358,158,6711,171,8221,0.287183633,1.131864102,0.903645794,1.417024833,0.452026814,DB0086410051358_,0.794013777,0.123865921,NA,10051358,Post transplant lymphoproliferative disorder,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,tacrolimus,DB00864
,173620,DB00230,10013395,57,19617,20,8631,0.457437123,1.253895914,0.74137014,2.205117692,0.624804344,DB0023010013395_,0.470316729,0.226255435,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,173653,DB00254,10061818,34,5901,38,3350,0.004499126,0.50796814,0.30957353,0.830575313,0.018775824,DB0025410061818_,3.975185191,-0.67733655,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,173656,DB08907,10020646,36,4217,62,3848,0.002228,0.529882397,0.340468631,0.813783734,0.010621741,DB0890710020646_,4.544852364,-0.635100189,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,canagliflozin,DB08907
,173664,DB00921,10061428,53,5792,38,4865,0.526244349,1.17149385,0.756450224,1.829843053,0.68414238,DB0092110061428_,0.379589225,0.158279729,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,buprenorphine,DB00921
,173674,DB06643,10041349,84,52337,23,7492,0.0081624,0.522842134,0.326150181,0.869739468,0.030282102,DB0664310041349_,3.497198444,-0.648475707,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,173690,DB00697,10022004,59,6037,14,1792,0.575048964,1.250913395,0.688003975,2.432126484,0.724646567,DB0069710022004_,0.322071237,0.223874001,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,173714,DB00588,10003285,80,16444,27,8441,0.065078473,1.520918152,0.971485298,2.449894959,0.152567576,DB0058810003285_,1.88014766,0.4193142,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,173749,DB00588,10005191,51,16473,19,8449,0.256795897,1.376719839,0.798313875,2.470835047,0.41767768,DB0058810005191_,0.873045244,0.319703741,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,173781,DB00153,10016825,40,7383,19,3420,0.889533871,0.975215006,0.550845488,1.785531051,0.954089642,DB0015310016825_,0.046997648,-0.025097313,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,ergocalciferol,DB00153
,173782,DB00121,10047942,81,4142,13,455,0.220845084,0.684519456,0.374896786,1.351468479,0.3745226,DB0012110047942_,0.98210313,-0.379038211,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,biotin,DB00121
,173786,DB00060,10066901,124,9384,33,2432,0.920825137,0.973830753,0.656854235,1.480359608,0.964924382,DB0006010066901_,0.035705541,-0.026517756,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,173799,DB00656,10045555,56,11957,41,6578,0.16787186,0.751442117,0.492716213,1.154463907,0.307953509,DB0065610045555_,1.177806453,-0.285761095,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,173803,DB00230,10011878,44,19630,18,8633,0.89054356,1.075028888,0.608179434,1.977892632,0.954671384,DB0023010011878_,0.046388098,0.072347534,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,pregabalin,DB00230
,173826,DB00656,10005724,44,11969,11,6608,0.016020662,2.208287999,1.121271918,4.745067128,0.05187596,DB0065610005724_,2.958899803,0.792217554,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,trazodone,DB00656
,173827,DB00656,10005750,106,11907,40,6579,0.045463283,1.464181717,1.00746239,2.165448287,0.116449269,DB0065610005750_,2.150299559,0.381296532,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,trazodone,DB00656
,173830,DB05259,10007882,41,11229,14,2714,0.304140299,0.707842833,0.377337249,1.407973429,0.470766879,DB0525910007882_,0.753392257,-0.345533197,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,glatiramer,DB05259
,173834,DB05259,10047571,105,11165,29,2699,0.511706446,0.875240099,0.5740782,1.373052867,0.672039768,DB0525910047571_,0.397437761,-0.133257031,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,glatiramer,DB05259
,173839,DB05259,10061296,77,11193,30,2698,0.036190261,0.61870348,0.399981752,0.97959652,0.097926807,DB0525910061296_,2.323534948,-0.480129152,NA,10061296,Motor dysfunction,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,173842,DB00051,10013946,67,25664,21,11399,0.202691221,1.417120659,0.856476918,2.437624116,0.352154844,DB0005110013946_,1.043684301,0.348627108,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,173843,DB00863,10022061,84,10589,10,5830,5.6033187601011e-08,4.624071056,2.391871272,10.00296593,1.07154044095495e-06,DB0086310022061_,13.74641328,1.531275498,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,173854,DB00635,10039020,19,33034,50,23744,4.57208498794946e-07,0.273140935,0.152019917,0.471722096,7.15766848768621e-06,DB0063510039020_,11.84732626,-1.297767373,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,173855,DB01175,10039020,33,10691,27,4865,0.025636644,0.556229803,0.323944183,0.962787212,0.074914862,DB0117510039020_,2.591402983,-0.586573755,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,173881,DB00196,10043554,53,5030,67,3218,0.000224338,0.506112412,0.345203328,0.738802764,0.001586631,DB0019610043554_,6.446142614,-0.680996477,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,fluconazole,DB00196
,173896,DB01175,10044565,154,10570,68,4824,0.884163281,1.033547849,0.770429922,1.398945145,0.951727419,DB0117510044565_,0.04947661,0.032997398,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,173901,DB05679,10037844,148,6783,77,4832,0.028626005,1.36919262,1.029968434,1.832226147,0.081666526,DB0567910037844_,2.505111076,0.314221238,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ustekinumab,DB05679
,173902,DB00531,10010264,61,7191,41,6475,0.163652693,1.339634748,0.885799613,2.044552647,0.302312955,DB0053110010264_,1.196292523,0.292397001,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,173903,DB00541,10010264,37,3097,25,4272,0.006340476,2.041339321,1.193574169,3.545557806,0.024750787,DB0054110010264_,3.698898008,0.713606122,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,vincristine,DB00541
,173912,DB00531,10016173,54,7198,58,6458,0.344144317,0.835330949,0.564847109,1.233582196,0.513471838,DB0053110016173_,0.666560094,-0.179927286,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclophosphamide,DB00531
,173913,DB00541,10016173,13,3121,38,4259,0.015460443,0.466893694,0.227814047,0.897872521,0.050474576,DB0054110016173_,2.986285522,-0.761653683,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,vincristine,DB00541
,173928,DB00480,10015967,176,67252,96,67566,1.02166792989414e-06,1.841873501,1.428020533,2.387866939,1.45711022991142e-05,DB0048010015967_,11.13647029,0.610783261,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,lenalidomide,DB00480
,173932,DB01611,10042128,63,11850,6,2355,0.101984208,2.086610639,0.905542785,5.90662867,0.213921867,DB0161110042128_,1.542144438,0.735541046,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,173933,DB01611,10070863,179,11734,24,2337,0.070653896,1.485396343,0.964276226,2.384944593,0.162450811,DB0161110070863_,1.817380026,0.395681634,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxychloroquine,DB01611
,173956,DB05351,10013700,63,2660,12,1119,0.009980191,2.208175307,1.174024348,4.516652447,0.035514697,DB0535110013700_,3.337808664,0.792166521,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,dexlansoprazole,DB05351
,173983,DB00877,10035664,37,1071,59,1372,0.345369117,0.803436521,0.513587976,1.242861914,0.514817095,DB0087710035664_,0.663943597,-0.2188571,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sirolimus,DB00877
,173989,DB00706,10058080,7,1068,44,15881,0.040347372,2.365555858,0.896757719,5.310137855,0.106324195,DB0070610058080_,2.241262413,0.861013029,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,tamsulosin,DB00706
,173994,DB01611,10058080,48,11865,19,2342,0.013050313,0.498674629,0.287121547,0.900073392,0.044018941,DB0161110058080_,3.123135256,-0.695801442,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,hydroxychloroquine,DB01611
,174007,DB00275,10011224,36,2024,18,1219,0.572971407,1.204439195,0.662910243,2.263598772,0.722935482,DB0027510011224_,0.324435297,0.18601406,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,olmesartan,DB00275
,174011,DB00588,10036790,131,16393,71,8397,0.709346875,0.94510475,0.701809596,1.281660218,0.826544135,DB0058810036790_,0.190501963,-0.056459511,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone propionate,DB00588
,174013,DB00275,10053762,63,1997,29,1208,0.27466616,1.313992607,0.828364968,2.129007561,0.437920838,DB0027510053762_,0.82571712,0.273070294,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,olmesartan,DB00275
,174088,DB00921,10000081,38,5807,27,4876,0.534528764,1.181747748,0.701658643,2.015796256,0.691101257,DB0092110000081_,0.369468929,0.166994485,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,buprenorphine,DB00921
,174091,DB00921,10027599,85,5760,19,4884,6.94202568741082e-09,3.792800059,2.282492694,6.617200519,1.61478889551853e-07,DB0092110027599_,15.63889142,1.333104548,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,buprenorphine,DB00921
,174097,DB01285,10013968,62,1214,25,584,0.557368085,1.19288343,0.730024927,2.00264758,0.710479695,DB0128510013968_,0.34181491,0.176373427,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,corticotropin,DB01285
,174112,DB00706,10047899,13,1062,155,15770,0.424544426,1.245409465,0.646258371,2.202722595,0.593350893,DB0070610047899_,0.52196933,0.219464363,NA,10047899,Weight increased,10022891,Investigations,Inv,tamsulosin,DB00706
,174113,DB01285,10047899,66,1210,32,577,1,0.983522396,0.627365194,1.569550518,1,DB0128510047899_,0,-0.01661487,NA,10047899,Weight increased,10022891,Investigations,Inv,corticotropin,DB01285
,174124,DB00051,10028735,66,25665,19,11401,0.100013345,1.543080971,0.914347804,2.724029735,0.210788659,DB0005110028735_,1.556899261,0.433781049,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,174125,DB00482,10028735,46,8213,10,3061,0.132810269,1.714416933,0.851998773,3.815254942,0.259718297,DB0048210028735_,1.348157709,0.539073042,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,celecoxib,DB00482
,174146,DB00641,10033557,131,13993,36,12439,1.37058651148051e-11,3.234463243,2.219955118,4.820741099,5.11005197932839e-10,DB0064110033557_,21.39464135,1.173862993,female,10033557,Palpitations,10007541,Cardiac disorders,Card,simvastatin,DB00641
,174207,DB00423,10012378,61,2406,29,1011,0.640066498,0.88390787,0.555477403,1.435853855,0.777078955,DB0042310012378_,0.252213319,-0.123402441,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,methocarbamol,DB00423
,174225,DB00423,10033371,156,2311,39,1001,0.00210471,1.732340117,1.202326673,2.548282246,0.010144369,DB0042310033371_,4.590836549,0.549473163,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,methocarbamol,DB00423
,174226,DB00461,10033371,49,1041,19,306,0.304453176,0.758235233,0.430631804,1.385555785,0.471126323,DB0046110033371_,0.75262902,-0.276761608,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,nabumetone,DB00461
,174234,DB00698,10003549,98,3050,22,407,0.04362956,0.594531371,0.366492267,1.003505098,0.112879865,DB0069810003549_,2.18143117,-0.519981795,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,nitrofurantoin,DB00698
,174253,DB00275,10003549,60,2000,40,1197,0.601517503,0.897781976,0.587735042,1.384186981,0.745796583,DB0027510003549_,0.293302393,-0.107828029,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,olmesartan,DB00275
,174255,DB00761,10024264,74,15233,46,8579,0.63388215,0.90599952,0.618105582,1.340338096,0.772335433,DB0076110024264_,0.258336324,-0.098716503,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,174257,DB06605,10024264,54,14019,46,12987,0.689722964,1.087460412,0.719691112,1.649299468,0.812888491,DB0660510024264_,0.207161336,0.083845081,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,174280,DB00030,10048959,49,2157,20,1801,0.006939991,2.045260525,1.18836558,3.646757609,0.02661795,DB0003010048959_,3.626169461,0.715525178,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,insulin human,DB00030
,174282,DB00188,10046735,48,7838,40,8788,0.198646924,1.345413672,0.864862681,2.103110934,0.3474355,DB0018810046735_,1.057176244,0.296701528,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,bortezomib,DB00188
,174328,DB00343,10033318,120,8616,46,5049,0.014965745,1.528658329,1.077574423,2.20094642,0.049230286,DB0034310033318_,3.011246276,0.424390442,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,diltiazem,DB00343
,174360,DB01222,10038683,46,9228,25,5380,0.806674197,1.07273753,0.644649509,1.824141119,0.895526273,DB0122210038683_,0.110343719,0.070213821,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,174362,DB01164,10049414,74,6450,87,7849,0.873531053,1.035075489,0.747400484,1.430301595,0.944995818,DB0116410049414_,0.056574777,0.034474361,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,calcium chloride,DB01164
,174364,DB01175,10005557,44,10680,28,4864,0.163696477,0.715679082,0.435125898,1.195322824,0.302372586,DB0117510005557_,1.196095293,-0.334523422,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,escitalopram,DB01175
,174410,DB00193,10019196,55,19265,21,8681,0.619647851,1.180150731,0.701733317,2.055792262,0.760331312,DB0019310019196_,0.274001004,0.165642168,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,174411,DB06228,10028391,45,15867,21,16055,0.002912702,2.168185289,1.264363242,3.833837248,0.013187557,DB0622810028391_,4.328481528,0.773890545,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,rivaroxaban,DB06228
,174420,DB00193,10061394,49,19271,8,8694,0.003995053,2.763177324,1.297099628,6.759011802,0.017062308,DB0019310061394_,4.070883477,1.016381222,female,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,174422,DB00635,10061394,60,32993,9,23785,2.70138419368479e-07,4.805947063,2.369585816,11.02019398,4.44342199818553e-06,DB0063510061394_,12.32408576,1.569854122,female,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,174424,DB00404,10064355,68,19824,30,9832,0.667580042,1.124175928,0.720991907,1.791082338,0.798132469,DB0040410064355_,0.225480694,0.117050258,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,174427,DB00586,10024264,36,7073,16,2789,0.757563584,0.887231951,0.479041618,1.715366173,0.864468915,DB0058610024264_,0.145639932,-0.11964883,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,174433,DB01012,10016322,59,10573,31,8654,0.055322775,1.557752164,0.991126017,2.492406733,0.134887912,DB0101210016322_,2.003311129,0.443243862,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,174499,DB00158,10061623,123,16692,52,8052,0.466460947,1.141016579,0.817720915,1.61180179,0.63318147,DB0015810061623_,0.456998215,0.131919601,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,174502,DB11089,10061623,63,10112,68,8339,0.134382892,0.764042915,0.532905044,1.093975336,0.261793909,DB1108910061623_,1.340197693,-0.26913132,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,174503,DB14500,10061623,68,7741,26,4047,0.191296805,1.367290654,0.857023347,2.242728287,0.338191857,DB1450010061623_,1.08414192,0.312831157,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,174506,DB00046,10028810,52,5407,27,4665,0.031675724,1.66154664,1.02277211,2.756282661,0.088398597,DB0004610028810_,2.425899184,0.50774888,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,insulin lispro,DB00046
,174507,DB00193,10028810,254,19066,69,8633,0.000104036,1.666785118,1.271048752,2.210440502,0.000825663,DB0019310028810_,7.099323361,0.510896692,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,tramadol,DB00193
,174508,DB00476,10028810,205,17052,46,6131,0.003092933,1.60237693,1.157188483,2.260090829,0.013869783,DB0047610028810_,4.278042687,0.471488108,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,duloxetine,DB00476
,174509,DB00973,10028810,57,3794,34,2987,0.2420771,1.319824478,0.845847975,2.087511483,0.400276575,DB0097310028810_,0.915599533,0.277498756,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ezetimibe,DB00973
,174519,DB01050,10043882,71,18037,25,9346,0.105726534,1.47154675,0.920486278,2.425114759,0.219711581,DB0105010043882_,1.515439588,0.386314059,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,ibuprofen,DB01050
,174520,DB00820,10048865,45,11870,13,5803,0.094634763,1.692229757,0.89624014,3.421831723,0.202703398,DB0082010048865_,1.596011461,0.526047042,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,tadalafil,DB00820
,174529,DB00682,10005555,60,19399,24,16340,0.001955469,2.105693008,1.291144101,3.53758772,0.009560921,DB0068210005555_,4.650071221,0.744644633,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,warfarin,DB00682
,174532,DB08932,10005555,68,19375,28,6569,0.410369678,0.823379713,0.522552294,1.329580206,0.579751524,DB0893210005555_,0.545155674,-0.194337809,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,macitentan,DB08932
,174538,DB08932,10062237,81,19362,38,6559,0.112350852,0.722095761,0.484853914,1.092604379,0.229606416,DB0893210062237_,1.47138867,-0.325597517,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,macitentan,DB08932
,174550,DB00722,10066152,32,25371,29,26003,0.701181792,1.130932148,0.662439836,1.938263722,0.820515905,DB0072210066152_,0.197821984,0.123042202,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,lisinopril,DB00722
,174552,DB05679,10025482,86,6845,34,4875,0.003711723,1.801352858,1.195765443,2.76921033,0.016057927,DB0567910025482_,4.131552685,0.58853797,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,174556,DB01067,10024855,30,4331,30,4793,0.69965294,1.106660024,0.643404708,1.903580902,0.81951728,DB0106710024855_,0.199039794,0.101346492,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,glipizide,DB01067
,174569,DB01109,10048959,47,4365,20,4250,0.001937447,2.288039835,1.326926071,4.083163322,0.009487633,DB0110910048959_,4.657766118,0.827695484,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,174590,DB00641,10017412,54,14070,28,12447,0.026062983,1.706068093,1.061075065,2.799131561,0.075857104,DB0064110017412_,2.578903918,0.534191362,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,simvastatin,DB00641
,174592,DB00091,10037844,155,5355,42,2628,0.000506361,1.811006658,1.275900023,2.620047288,0.003120316,DB0009110037844_,5.769820938,0.593882856,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cyclosporine,DB00091
,174601,DB00668,10008531,139,9952,44,4259,0.087884464,1.351866893,0.954869187,1.947138288,0.191661635,DB0066810008531_,1.65202378,0.301486521,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,174603,DB00030,10012735,100,2106,52,1769,0.005977234,1.615157064,1.136669632,2.318002072,0.023592102,DB0003010012735_,3.746843303,0.479432205,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,insulin human,DB00030
,174607,DB00321,10022004,52,7395,12,2838,0.123519587,1.662992181,0.874405509,3.427922295,0.246435048,DB0032110022004_,1.400656817,0.508618498,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,174608,DB00668,10022004,104,9987,36,4267,0.307940372,1.234256893,0.835971667,1.860142679,0.475136023,DB0066810022004_,0.744154151,0.210469083,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,174609,DB00678,10022004,77,15522,44,10680,0.354409376,1.204070151,0.820105213,1.787373484,0.524249441,DB0067810022004_,0.645787675,0.185707611,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,174612,DB01409,10022004,37,5994,17,3949,0.264596101,1.433864246,0.786151734,2.719533396,0.426550661,DB0140910022004_,0.852024137,0.36037307,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,174613,DB09140,10022004,41,3700,18,1780,0.888914566,1.095775262,0.613553094,2.032524983,0.953911952,DB0914010022004_,0.047183905,0.091462114,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,174614,DB01109,10025482,72,4340,29,4241,3.2872163325444e-05,2.426044875,1.552613019,3.88109238,0.000307435,DB0110910025482_,8.087248327,0.886262308,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,174615,DB00524,10037660,54,1523,28,1316,0.032423738,1.666160846,1.030071908,2.748888891,0.090019323,DB0052410037660_,2.407730928,0.510522085,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,174620,DB00193,10043224,43,19277,13,8689,0.247668055,1.490919089,0.786437532,3.023666103,0.406948479,DB0019310043224_,0.899068689,0.399392768,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,174650,DB00656,10035226,27,11986,52,6567,4.73182768983262e-08,0.284501229,0.171628925,0.46182613,9.18921986163653e-07,DB0065610035226_,13.90006461,-1.257017706,male,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,trazodone,DB00656
,174652,DB01068,10035226,28,13735,30,6810,0.004714085,0.462769383,0.266157007,0.802290288,0.019510271,DB0106810035226_,3.93681426,-0.770526443,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,clonazepam,DB01068
,174694,DB01610,10011906,43,898,64,1154,0.485599716,0.863473269,0.566762399,1.30464543,0.649625274,DB0161010011906_,0.431359584,-0.146792338,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,valganciclovir,DB01610
,174707,DB00563,10040872,46,46600,22,15326,0.159406375,0.687671602,0.405187568,1.200751359,0.296668429,DB0056310040872_,1.215140164,-0.374443878,NA,10040872,Skin infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,174712,DB01611,10013971,54,11859,12,2349,0.739223269,0.891328132,0.470030047,1.833627168,0.850033188,DB0161110013971_,0.162479886,-0.115042645,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxychloroquine,DB01611
,174727,DB08877,10029410,37,3252,37,3192,1,0.981549914,0.603500394,1.596355832,1,DB0887710029410_,0,-0.018622412,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,ruxolitinib,DB08877
,174737,DB00338,10021654,48,33626,20,22252,0.083603197,1.588185411,0.924598484,2.825838258,0.184435985,DB0033810021654_,1.690452842,0.462592114,NA,10021654,Increased appetite,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,174758,DB00188,10027175,52,7834,34,8794,0.01672868,1.716757397,1.091888307,2.731300392,0.053692331,DB0018810027175_,2.924485096,0.540437277,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,174759,DB00722,10042128,119,25284,95,25937,0.074741564,1.284972773,0.972416004,1.701867717,0.169426243,DB0072210042128_,1.775337591,0.25073753,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,174795,DB00186,10026749,41,16860,18,9990,0.345518255,1.349629581,0.757734943,2.497175402,0.514937196,DB0018610026749_,0.663710336,0.29983017,NA,10026749,Mania,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,174796,DB00186,10033664,56,16845,20,9988,0.05672026,1.660189539,0.98014232,2.922807993,0.137314487,DB0018610033664_,1.98548146,0.506931776,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,174813,DB00476,10002368,83,17174,53,6124,0.001220565,0.558454755,0.390430391,0.804841177,0.006486568,DB0047610002368_,5.038021752,-0.582581676,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,174899,DB00193,10016288,59,19261,66,8636,4.90188234283494e-07,0.40082555,0.277002852,0.578857266,7.61726144731991e-06,DB0019310016288_,11.78509364,-0.914228984,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,tramadol,DB00193
,174902,DB00959,10016288,63,8015,34,4968,0.600246609,1.148542166,0.744036243,1.800693036,0.744697071,DB0095910016288_,0.29477776,0.138493456,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,methylprednisolone,DB00959
,174912,DB00264,10042361,41,29566,74,24818,7.01690868556948e-05,0.465081605,0.309396573,0.690493959,0.000587949,DB0026410042361_,7.438871197,-0.765542395,NA,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,174942,DB00999,10013082,63,21367,17,12222,0.004919186,2.11973329,1.2244375,3.866320842,0.020207987,DB0099910013082_,3.901677354,0.751290274,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,174943,DB00722,10013754,58,25345,50,25982,0.387022847,1.189148845,0.800189479,1.772718113,0.557134947,DB0072210013754_,0.584947793,0.173237795,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,174944,DB00999,10013754,68,21362,22,12217,0.020725001,1.767672746,1.07856829,3.004915112,0.063558121,DB0099910013754_,2.755800502,0.569663849,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,174950,DB00193,10014387,45,19275,6,8696,0.002119773,3.383292613,1.438280374,9.706110275,0.010202938,DB0019310014387_,4.585079548,1.218849381,female,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,tramadol,DB00193
,174960,DB00601,10043554,41,864,56,855,0.143879894,0.724647753,0.466735281,1.117036626,0.275336392,DB0060110043554_,1.289761685,-0.3220696,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,linezolid,DB00601
,174971,DB08935,10028813,36,496,50,763,0.650226947,1.107493866,0.690015756,1.762505802,0.784918841,DB0893510028813_,0.242174953,0.102099685,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,obinutuzumab,DB08935
,174973,DB08935,10047700,28,504,30,783,0.171891188,1.449549325,0.823661293,2.544249393,0.313304201,DB0893510047700_,1.160580674,0.371252698,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,obinutuzumab,DB08935
,174982,DB01065,10033425,102,4229,44,3007,0.00640813,1.648216648,1.142739359,2.411507072,0.024948187,DB0106510033425_,3.690954105,0.499693884,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,melatonin,DB01065
,174990,DB01076,10013082,61,25686,52,25531,0.451615734,1.165993544,0.791844248,1.722457929,0.619250349,DB0107610013082_,0.479245646,0.153573551,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,174999,DB06282,10013709,90,1450,32,501,0.915015894,0.971779581,0.633504786,1.523570475,0.961992279,DB0628210013709_,0.038748855,-0.028626269,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,levocetirizine,DB06282
,175017,DB00153,10000081,130,7293,44,3395,0.070886715,1.375377324,0.967615852,1.987598967,0.162865024,DB0015310000081_,1.814833494,0.318728111,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,175026,DB06674,10016256,149,4357,37,1453,0.120896354,1.342873372,0.926384931,1.990550673,0.242753192,DB0667410016256_,1.415710024,0.294811626,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,golimumab,DB06674
,175050,DB01142,10041349,38,1702,12,772,0.354207449,1.436172613,0.729725634,3.036212437,0.524068717,DB0114210041349_,0.646132463,0.361981667,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,doxepin,DB01142
,175055,DB08880,10029331,48,3290,7,802,0.233314343,1.671361428,0.748168222,4.395380615,0.389904373,DB0888010029331_,0.941853767,0.513638521,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,teriflunomide,DB08880
,175058,DB00773,10012174,39,2284,42,2785,0.576253079,1.132226581,0.710395662,1.800715947,0.725543658,DB0077310012174_,0.320834032,0.12418612,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,etoposide,DB00773
,175059,DB01181,10012735,22,551,42,878,0.59950771,0.834791673,0.469143259,1.448380693,0.744147155,DB0118110012735_,0.295516475,-0.180573078,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ifosfamide,DB01181
,175068,DB00563,10020942,26,46620,38,15310,4.21235567919993e-09,0.22471762,0.130959113,0.380005364,1.02853477963558e-07,DB0056310020942_,16.08996041,-1.492910688,male,10020942,Hypoalbuminaemia,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,175074,DB00741,10021015,39,4055,38,3136,0.355625773,0.793748473,0.493272852,1.278293349,0.525353985,DB0074110021015_,0.643682987,-0.230988653,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,hydrocortisone,DB00741
,175075,DB00773,10021015,46,2277,36,2791,0.056564463,1.566058839,0.986765066,2.502742234,0.137061595,DB0077310021015_,1.987324859,0.44856217,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,etoposide,DB00773
,175076,DB00987,10021015,25,2079,37,2891,0.897135918,0.93957728,0.540358856,1.608780597,0.956338178,DB0098710021015_,0.044643686,-0.062325206,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,cytarabine,DB00987
,175087,DB01181,10033661,18,555,48,872,0.069318742,0.589384836,0.319184077,1.044609097,0.160116273,DB0118110033661_,1.831855021,-0.528675938,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,ifosfamide,DB01181
,175097,DB00531,10063743,34,7218,34,6482,0.715428575,0.89804027,0.540872353,1.490984097,0.831526656,DB0053110063743_,0.184491923,-0.107540368,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,cyclophosphamide,DB00531
,175103,DB08880,10047942,38,3300,14,795,0.215196088,0.65397238,0.344354652,1.313347133,0.367634809,DB0888010047942_,1.0006652,-0.42469016,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,teriflunomide,DB08880
,175144,DB00480,10010264,25,67403,37,67625,0.161824136,0.677906384,0.391112355,1.156822034,0.299830643,DB0048010010264_,1.204537488,-0.388746077,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,175145,DB00581,10012174,43,2070,46,2023,0.748068365,0.913588119,0.585708338,1.422484562,0.856905279,DB0058110012174_,0.154427893,-0.090375445,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,lactulose,DB00581
,175147,DB00695,10014418,47,28002,22,20506,0.088122075,1.564452621,0.923942176,2.726968821,0.192125514,DB0069510014418_,1.649606399,0.447536,NA,10014418,Electrolyte imbalance,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,175152,DB01075,10034474,32,19916,19,11078,0.883914953,0.936821594,0.514803305,1.750132474,0.951596508,DB0107510034474_,0.04961417,-0.065262416,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,175160,DB00028,10006784,53,13405,24,5591,0.709010163,0.921065746,0.558072756,1.56171425,0.826334951,DB0002810006784_,0.190755078,-0.08222386,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,175161,DB00207,10036790,63,9017,58,5397,0.023229591,0.650179617,0.447077162,0.946947413,0.069420703,DB0020710036790_,2.667570139,-0.43050662,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,175162,DB01136,10036790,54,9830,34,11081,0.007410325,1.790291856,1.143469106,2.838636607,0.028021923,DB0113610036790_,3.574768125,0.582378654,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,175172,DB00213,10013774,53,18842,6,13415,1.78465869227647e-07,6.28837995,2.704519447,17.90653611,3.06399436489138e-06,DB0021310013774_,12.69579115,1.838703478,female,10013774,Dry eye,10015919,Eye disorders,Eye,pantoprazole,DB00213
,175183,DB01104,10013774,48,15415,8,7278,0.003734003,2.832720227,1.327446181,6.937376155,0.016129701,DB0110410013774_,4.127092933,1.041237461,female,10013774,Dry eye,10015919,Eye disorders,Eye,sertraline,DB01104
,175194,DB01076,10015967,57,25690,33,25550,0.014825294,1.717831667,1.099424314,2.724102696,0.048856927,DB0107610015967_,3.018859108,0.541062837,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,atorvastatin,DB01076
,175198,DB01020,10037087,40,1773,25,1853,0.045675015,1.671951371,0.985067015,2.888543087,0.116860638,DB0102010037087_,2.146773183,0.51399143,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,isosorbide mononitrate,DB01020
,175224,DB00121,10053762,111,4112,6,462,0.084711379,2.078302913,0.917783613,5.817229931,0.186282824,DB0012110053762_,1.680489203,0.731551653,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,biotin,DB00121
,175237,DB00843,10002855,44,2150,21,2152,0.005595271,2.096834405,1.21566341,3.725821208,0.022385341,DB0084310002855_,3.799348935,0.740428781,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,donepezil,DB00843
,175238,DB00843,10003988,31,2163,21,2152,0.209150677,1.46854811,0.81434738,2.698146177,0.360196652,DB0084310003988_,1.02110514,0.384274233,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,donepezil,DB00843
,175239,DB00343,10012378,66,8670,29,5066,0.240206862,1.329791054,0.84586727,2.137975809,0.398073096,DB0034310012378_,0.921119633,0.285021828,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,diltiazem,DB00343
,175240,DB00343,10037377,49,8687,34,5061,0.427077804,0.839640114,0.530409286,1.343133508,0.595703791,DB0034310037377_,0.518011731,-0.174781915,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,175243,DB00182,10046735,51,5143,16,2836,0.053808147,1.757567723,0.983905622,3.308570978,0.1321511,DB0018210046735_,2.023809311,0.563930878,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,amphetamine,DB00182
,175244,DB00829,10046735,67,7985,25,4429,0.10106108,1.486457749,0.924857617,2.46031582,0.212409282,DB0082910046735_,1.549240291,0.39639594,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,diazepam,DB00829
,175264,DB06285,10029148,80,8770,9,1097,0.866717395,1.111876378,0.555229947,2.526983904,0.93987651,DB0628510029148_,0.062006785,0.106049019,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,teriparatide,DB06285
,175269,DB00327,10013710,53,6085,54,4208,0.048249019,0.678771006,0.454775967,1.012658957,0.121798365,DB0032710013710_,2.105388346,-0.38747146,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,175270,DB00455,10013710,71,9330,20,5098,0.007935152,1.939673426,1.165739953,3.368271525,0.029595318,DB0045510013710_,3.520139097,0.662519622,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,175271,DB01118,10013710,80,2983,176,4533,0.006292272,0.690764358,0.521381718,0.908659848,0.024599147,DB0111810013710_,3.705043507,-0.36995653,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,175291,DB00213,10018985,21,18874,31,13390,0.010626111,0.48059434,0.262353636,0.863970936,0.037358033,DB0021310018985_,3.287207317,-0.732731732,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,175296,DB01020,10020772,29,1784,33,1845,0.798060866,0.908872689,0.529948741,1.551010245,0.890838937,DB0102010020772_,0.115591635,-0.09555025,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,isosorbide mononitrate,DB01020
,175297,DB01377,10020772,54,3742,28,2642,0.214498207,1.361583715,0.844848798,2.238819621,0.366895644,DB0137710020772_,1.00267782,0.308648518,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,magnesium oxide,DB01377
,175299,DB00333,10000381,45,3026,56,3096,0.366871538,0.822187354,0.540865027,1.2437015,0.536509312,DB0033310000381_,0.62267136,-0.195786985,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,methadone,DB00333
,175301,DB00555,10000381,15,7032,36,3450,7.67427840581706e-08,0.204462824,0.103861967,0.383481143,1.42506822957896e-06,DB0055510000381_,13.46129086,-1.587369108,male,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lamotrigine,DB00555
,175308,DB00295,10014625,53,14610,71,9531,9.38994008649962e-05,0.486980917,0.334247062,0.705671225,0.000755941,DB0029510014625_,7.187547881,-0.719530341,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,morphine,DB00295
,175320,DB00115,10057362,56,18369,36,10436,0.587602988,0.883766999,0.570813679,1.384037003,0.734643481,DB0011510057362_,0.308369957,-0.123561827,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,175346,DB01248,10020772,36,2664,15,1359,0.554621622,1.224232643,0.65105368,2.415695338,0.70812299,DB0124810020772_,0.345137486,0.202314234,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,docetaxel,DB01248
,175350,DB00112,10021027,53,5880,7,4084,1.01795341574849e-06,5.258141385,2.379025141,13.72585391,1.4533897627892e-05,DB0011210021027_,11.13902687,1.659777615,female,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,bevacizumab,DB00112
,175361,DB00635,10029223,48,33005,34,23760,1,1.016317134,0.641239381,1.626921828,1,DB0063510029223_,0,0.01618544,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,175380,DB11097,10003549,33,821,26,657,1,1.015684659,0.582521712,1.787673591,1,DB1109710003549_,0,0.015562926,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,plantago seed,DB11097
,175388,DB11097,10010774,36,818,29,654,1,0.992500526,0.584739785,1.697469159,1,DB1109710010774_,0,-0.007527736,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,plantago seed,DB11097
,175394,DB11097,10013573,35,819,25,658,0.692786873,1.124678731,0.646843264,1.981813581,0.814936921,DB1109710013573_,0.204644567,0.117497422,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,plantago seed,DB11097
,175396,DB00497,10013990,45,19222,30,16345,0.353649481,1.275481487,0.785661879,2.097900291,0.523478903,DB0049710013990_,0.64725855,0.243323744,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,oxycodone,DB00497
,175397,DB01050,10013990,62,18046,18,9353,0.032819109,1.78517494,1.041671111,3.208740454,0.090891402,DB0105010013990_,2.398089874,0.579516416,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,ibuprofen,DB01050
,175400,DB11097,10016256,77,777,61,622,1,1.010479629,0.700415431,1.462907233,1,DB1109710016256_,0,0.010425098,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,plantago seed,DB11097
,175403,DB00482,10027175,80,8179,21,3050,0.177015308,1.420509815,0.867823991,2.42367389,0.320063751,DB0048210027175_,1.139235082,0.351015832,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,175411,DB00186,10031009,47,16854,22,9986,0.385448243,1.265803754,0.74730058,2.206914738,0.555592502,DB0018610031009_,0.587720163,0.235707299,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,175416,DB11089,10031009,35,10140,20,8387,0.22210162,1.44742959,0.812072729,2.648294476,0.376174799,DB1108910031009_,0.977701353,0.369789287,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,175469,DB00557,10029354,34,5953,20,3047,0.665750035,0.870152972,0.485768217,1.598185766,0.796678137,DB0055710029354_,0.227304525,-0.139086253,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,hydroxyzine,DB00557
,175488,DB00999,10005746,33,21397,17,12222,0.770820928,1.108813625,0.599839803,2.123413199,0.874483718,DB0099910005746_,0.134121604,0.103290637,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,hydrochlorothiazide,DB00999
,175504,DB00112,10030095,38,5895,36,4055,0.191547613,0.726122259,0.447174987,1.181061945,0.338566943,DB0011210030095_,1.083033442,-0.320036878,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,175570,DB00853,10013573,20,1801,31,2235,0.480611746,0.800674043,0.430941951,1.455815494,0.645393246,DB0085310013573_,0.437895464,-0.222301352,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,temozolomide,DB00853
,175585,DB00635,10061225,57,32996,24,23770,0.031593792,1.710906403,1.044551487,2.883663959,0.088213599,DB0063510061225_,2.427994145,0.53702329,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,175598,DB00112,10061169,54,5879,21,4070,0.024822189,1.780085355,1.055582797,3.1082199,0.073099684,DB0011210061169_,2.615931236,0.576661315,NA,10061169,Embolism,10047065,Vascular disorders,Vasc,bevacizumab,DB00112
,175648,DB01073,10035528,60,1005,115,1535,0.174291506,0.796950599,0.567319159,1.110251607,0.316533282,DB0107310035528_,1.150326887,-0.226962585,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,fludarabine,DB01073
,175649,DB00073,10028836,34,7372,17,6390,0.067675615,1.733514682,0.940908849,3.312110084,0.157163364,DB0007310028836_,1.85046948,0.550150956,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,rituximab,DB00073
,175651,DB01050,10019063,48,18060,61,9310,3.57911666606347e-06,0.405654104,0.271759452,0.602481843,4.4126210866547e-05,DB0105010019063_,10.0284566,-0.902254443,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,175705,DB00544,10001760,33,2402,21,2632,0.055342747,1.721700273,0.963843153,3.140833106,0.134924094,DB0054410001760_,2.003042928,0.543312334,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,fluorouracil,DB00544
,175780,DB00073,10022611,46,7360,26,6381,0.096624798,1.533843546,0.927242848,2.588041642,0.205707564,DB0007310022611_,1.58129971,0.427776707,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rituximab,DB00073
,175788,DB11065,10000081,143,3043,71,2617,0.000153072,1.731963706,1.287506121,2.347497638,0.001147111,DB1106510000081_,6.770508956,0.549255855,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,pancrelipase amylase,DB11065
,175796,DB11065,10053762,52,3134,31,2657,0.14878071,1.422026825,0.891512573,2.302769339,0.282310123,DB1106510053762_,1.264749086,0.352083196,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,pancrelipase amylase,DB11065
,175798,DB11065,10061428,54,3132,41,2647,0.678200555,1.113074708,0.725379625,1.719466831,0.805044441,DB1106510061428_,0.216857797,0.107126193,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,pancrelipase amylase,DB11065
,175847,DB00567,10046306,44,4475,9,2072,0.024975643,2.263403342,1.08786471,5.282705679,0.073418033,DB0056710046306_,2.611585691,0.816869584,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,cephalexin,DB00567
,175848,DB00567,10047895,81,4438,42,2039,0.556868887,0.886087983,0.60069897,1.323840192,0.71013481,DB0056710047895_,0.342300454,-0.12093903,NA,10047895,Weight decreased,10022891,Investigations,Inv,cephalexin,DB00567
,175859,DB06273,10040047,32,5063,19,1391,0.010002644,0.46277537,0.253560116,0.867003823,0.035572928,DB0627310040047_,3.336170393,-0.770513505,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,tocilizumab,DB06273
,175869,DB00650,10061428,29,2102,55,1959,0.001905835,0.49148808,0.300863461,0.787988334,0.009354784,DB0065010061428_,4.67186743,-0.710317593,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,leucovorin,DB00650
,175870,DB00762,10061428,28,1135,37,1332,0.705843699,0.888158311,0.519989538,1.50165242,0.823703986,DB0076210061428_,0.193944054,-0.118605274,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,irinotecan,DB00762
,175881,DB01036,10053762,47,1454,15,407,0.641543211,0.877117713,0.475961466,1.707020574,0.778200742,DB0103610053762_,0.250770765,-0.131114073,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tolterodine,DB01036
,175885,DB00997,10003658,44,5287,35,3479,0.420132,0.827260702,0.517486175,1.33144804,0.589047585,DB0099710003658_,0.529248308,-0.189635395,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,doxorubicin,DB00997
,175926,DB00341,10061623,56,11349,24,5044,1,1.037008191,0.631484494,1.751703217,1,DB0034110061623_,0,0.036339828,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,175933,DB01016,10070863,17,1084,48,1180,0.000573216,0.385705553,0.20660901,0.68779025,0.003459303,DB0101610070863_,5.666688172,-0.952681016,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,glyburide,DB01016
,175934,DB00252,10027175,43,2189,29,1879,0.341725355,1.272699649,0.773085961,2.12288756,0.510986419,DB0025210027175_,0.671412266,0.241140352,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,phenytoin,DB00252
,175957,DB00958,10061822,37,4557,13,2572,0.182577153,1.606288803,0.832645057,3.299421981,0.327155257,DB0095810061822_,1.117320428,0.473926427,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,carboplatin,DB00958
,175971,DB00112,10047942,200,5733,28,4063,1.76226034931699e-21,5.061530265,3.389097779,7.828451836,2.14449135563876e-19,DB0011210047942_,42.98621437,1.621668862,female,10047942,White blood cell count decreased,10022891,Investigations,Inv,bevacizumab,DB00112
,175994,DB00734,10006093,36,4014,31,4871,0.176060442,1.409160881,0.845742821,2.360393006,0.318759383,DB0073410006093_,1.143318745,0.342994407,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,risperidone,DB00734
,175995,DB00321,10010071,39,7408,39,2811,3.26803273176599e-05,0.379495634,0.236595742,0.608734185,0.000305913,DB0032110010071_,8.092211324,-0.968912187,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,175997,DB00490,10021097,50,4020,38,1538,0.002491265,0.503452434,0.322187042,0.79244349,0.011627968,DB0049010021097_,4.45434201,-0.686266042,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,buspirone,DB00490
,175999,DB00557,10021143,30,5957,35,3032,0.000924556,0.43630753,0.258213757,0.733099669,0.005165115,DB0055710021143_,5.265827932,-0.82940794,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxyzine,DB00557
,176070,DB00472,10037423,47,10712,24,4288,0.356865851,0.783911605,0.469105924,1.342191303,0.526549658,DB0047210037423_,0.641409634,-0.243459014,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,176076,DB00404,10047943,55,19837,15,9847,0.041365185,1.8200842,1.013210205,3.470454852,0.108462656,DB0040410047943_,2.221349353,0.598882764,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,alprazolam,DB00404
,176080,DB00480,10007554,144,67284,175,67487,0.092635103,0.825342181,0.657177303,1.035202119,0.199444043,DB0048010007554_,1.612221567,-0.191957214,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,lenalidomide,DB00480
,176092,DB00904,10037437,36,23033,27,14429,0.517745356,0.835275788,0.49290516,1.431160482,0.677263695,DB0090410037437_,0.389694576,-0.179993323,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,176103,DB00169,10021654,58,38633,17,18158,0.106342578,1.603560409,0.920557963,2.938359111,0.220695169,DB0016910021654_,1.510972857,0.472226413,NA,10021654,Increased appetite,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,176111,DB00413,10041349,56,2143,33,1174,0.737406204,0.929672317,0.590337794,1.484878857,0.848630564,DB0041310041349_,0.16413133,-0.072923102,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,pramipexole,DB00413
,176113,DB00669,10041349,74,6303,10,1087,0.538196882,1.276146884,0.653786299,2.779766356,0.694154495,DB0066910041349_,0.365060728,0.243845291,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,sumatriptan,DB00669
,176114,DB00820,10041349,112,11803,54,5762,1,1.012528414,0.724276409,1.430499164,1,DB0082010041349_,0,0.012450582,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,176116,DB06228,10041349,103,15809,36,16040,6.27869958761231e-09,2.902949876,1.967203471,4.372008962,1.47859059651583e-07,DB0622810041349_,15.72700632,1.065727419,female,10041349,Somnolence,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,176121,DB00230,10049564,95,19579,31,8620,0.174357365,1.349140172,0.890311092,2.096119515,0.316580895,DB0023010049564_,1.150176477,0.29946748,NA,10049564,Impaired driving ability,10041244,Social circumstances,SocCi,pregabalin,DB00230
,176145,DB00761,10049848,110,15197,66,8559,0.694008785,0.938675281,0.684760697,1.295278005,0.815795966,DB0076110049848_,0.203590997,-0.063285673,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,176147,DB09270,10049848,32,3082,21,2347,0.676668845,1.160361719,0.646899466,2.12325019,0.803963008,DB0927010049848_,0.218202021,0.148731784,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,ubidecarenone,DB09270
,176152,DB00656,10061818,76,11937,31,6588,0.187530066,1.353017927,0.879160711,2.128599741,0.333480056,DB0065610061818_,1.098172218,0.302337599,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,176154,DB01068,10061818,65,13698,43,6797,0.15179014,0.750116848,0.501918872,1.131000269,0.286407797,DB0106810061818_,1.25033862,-0.287526288,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,176190,DB00820,10038428,82,11833,37,5779,0.76899364,1.082348976,0.724652125,1.644011124,0.873452361,DB0082010038428_,0.135301689,0.079133657,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,tadalafil,DB00820
,176192,DB08932,10005724,218,19225,42,6555,0.000425834,1.769814458,1.265501789,2.527875348,0.002699489,DB0893210005724_,5.914692762,0.570874715,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,macitentan,DB08932
,176195,DB00331,10023379,44,24902,41,20711,0.663028724,0.892559441,0.569633455,1.401208029,0.794569675,DB0033110023379_,0.2299546,-0.113662166,NA,10023379,Ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,176204,DB01136,10018838,29,9855,32,11083,1,1.019177649,0.594411722,1.740861397,1,DB0113610018838_,0,0.018996075,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,carvedilol,DB01136
,176206,DB00121,10018884,46,4177,10,458,0.067242582,0.504467207,0.248969108,1.128954762,0.156434151,DB0012110018884_,1.855120116,-0.684252443,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,biotin,DB00121
,176225,DB00678,10047943,40,15559,26,10698,0.9004311,1.05781556,0.629412686,1.806629671,0.956698706,DB0067810047943_,0.044266769,0.05620599,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,losartan,DB00678
,176229,DB00316,10017822,78,65396,34,36919,0.237489597,1.295146029,0.855147537,1.999272664,0.394877063,DB0031610017822_,0.929180796,0.258623453,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,176286,DB00524,10062237,31,1546,24,1320,0.78545457,1.102779098,0.622965072,1.974336318,0.883669115,DB0052410062237_,0.12367259,0.097833446,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,metolazone,DB00524
,176287,DB00688,10062237,52,6438,65,5313,0.031409202,0.660236312,0.448640989,0.967457766,0.087796127,DB0068810062237_,2.432737896,-0.41515746,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,mycophenolate mofetil,DB00688
,176288,DB00736,10062237,57,10534,49,5504,0.013414863,0.607802875,0.406985284,0.910732039,0.044984329,DB0073610062237_,3.101441095,-0.497904668,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,esomeprazole,DB00736
,176289,DB01118,10062237,13,3050,38,4671,0.044173648,0.523966955,0.255660459,1.007580181,0.113943518,DB0111810062237_,2.172052407,-0.646326659,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,amiodarone,DB01118
,176290,DB01390,10062237,30,1379,33,1484,1,0.978315353,0.572964116,1.664463824,1,DB0139010062237_,0,-0.021923214,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,sodium bicarbonate,DB01390
,176291,DB06724,10062237,42,7887,22,3897,0.894102713,0.943295349,0.549544728,1.661707259,0.955860142,DB0672410062237_,0.045143671,-0.058375844,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,calcium carbonate,DB06724
,176301,DB00829,10022004,57,7995,24,4430,0.295372657,1.315958203,0.802381276,2.220586501,0.461283957,DB0082910022004_,0.773741466,0.274565072,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,176303,DB00213,10057362,32,18863,22,13399,1,1.033212846,0.581720737,1.867171372,1,DB0021310057362_,0,0.032673216,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,176314,DB00654,10047899,34,3782,18,2580,0.478517495,1.288509722,0.705790447,2.428966157,0.64381196,DB0065410047899_,0.440348583,0.253486296,NA,10047899,Weight increased,10022891,Investigations,Inv,latanoprost,DB00654
,176319,DB06228,10049438,33,15879,26,16050,0.363755797,1.282885607,0.743748546,2.234599132,0.533317778,DB0622810049438_,0.628637825,0.249111921,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,176364,DB00051,10058046,54,25677,38,11382,0.031514441,0.629927176,0.408106165,0.981141652,0.08804348,DB0005110058046_,2.429924492,-0.46215106,NA,10058046,Post procedural complication,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,176372,DB00588,10012374,45,16479,12,8456,0.048819861,1.924221958,1.000428826,3.998591217,0.122799511,DB0058810012374_,2.097202247,0.654521708,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,fluticasone propionate,DB00588
,176375,DB06700,10016173,56,2169,10,608,0.227413362,1.569504763,0.787376693,3.471259857,0.382637321,DB0670010016173_,0.960667682,0.450760132,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,desvenlafaxine,DB06700
,176376,DB00829,10020937,124,7928,33,4421,7.43954490557419e-05,2.095277556,1.414595947,3.182188739,0.000618433,DB0082910020937_,7.388322091,0.739686029,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,176402,DB00169,10051290,77,38614,29,18146,0.34860614,1.247719499,0.804153169,1.984871798,0.518129058,DB0016910051290_,0.657530921,0.221317484,NA,10051290,Central nervous system lesion,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,176409,DB00635,10020141,51,33002,52,23742,0.088813634,0.70559212,0.469791978,1.059257604,0.193274526,DB0063510020141_,1.643643684,-0.348717943,NA,10020141,Histoplasmosis,10021881,Infections and infestations,Infec,prednisone,DB00635
,176412,DB01190,10040753,63,4871,30,2255,0.910846482,0.972159072,0.617972828,1.560393611,0.959852455,DB0119010040753_,0.040975699,-0.028235834,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,clindamycin,DB01190
,176413,DB00563,10067152,68,46578,14,15334,0.12403201,1.5989646,0.890509349,3.079513695,0.247142583,DB0056310067152_,1.397789851,0.469356295,NA,10067152,Oral herpes,10021881,Infections and infestations,Infec,methotrexate,DB00563
,176420,DB00273,10013654,36,8445,19,2174,0.017570886,0.487786388,0.271863643,0.902209605,0.055849899,DB0027310013654_,2.885087569,-0.717877699,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,176421,DB00281,10013654,45,11413,58,5613,1.45750904091702e-06,0.381597039,0.252290942,0.573952672,2.00789439939748e-05,DB0028110013654_,10.81583885,-0.963390098,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,lidocaine,DB00281
,176471,DB00264,10048865,97,29510,80,24812,0.939815563,1.019471116,0.750043884,1.389000135,0.979230668,DB0026410048865_,0.020988048,0.019283979,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,metoprolol,DB00264
,176473,DB01076,10048865,81,25666,85,25498,0.756089546,0.946684859,0.689214251,1.299559994,0.863253136,DB0107610048865_,0.14704731,-0.054789019,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,atorvastatin,DB01076
,176476,DB11089,10048865,33,10142,23,8384,0.59169127,1.186068013,0.675118087,2.117252504,0.737964651,DB1108910048865_,0.303859353,0.170643645,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,docusate,DB11089
,176479,DB00813,10061309,147,10425,153,10015,0.522350321,0.923019986,0.72969489,1.16717929,0.680961055,DB0081310061309_,0.384250162,-0.080104391,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fentanyl,DB00813
,176481,DB06724,10013971,65,7864,19,3900,0.047234618,1.696536817,1.003000541,3.000627935,0.119893963,DB0672410013971_,2.121147572,0.528589007,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,176483,DB09065,10053762,21,731,43,1894,0.398368987,1.265274729,0.70805077,2.196756747,0.56817216,DB0906510053762_,0.565330807,0.235289276,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,cobicistat,DB09065
,176520,DB01024,10013710,39,2172,74,2046,0.000386457,0.496535733,0.326347079,0.74525757,0.002492766,DB0102410013710_,5.994362503,-0.700099829,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,mycophenolic acid,DB01024
,176529,DB01020,10028334,33,1780,25,1853,0.237101382,1.374010421,0.788987741,2.420665525,0.394456143,DB0102010028334_,0.930247317,0.317733778,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,isosorbide mononitrate,DB01020
,176530,DB01020,10033371,63,1750,34,1844,0.00188535,1.952109837,1.259586609,3.072267091,0.009275018,DB0102010033371_,4.680430727,0.668910755,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,isosorbide mononitrate,DB01020
,176551,DB00924,10010264,233,9929,70,4181,0.013002301,1.401644853,1.065862427,1.862666952,0.0438836,DB0092410010264_,3.126214611,0.337646442,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,176552,DB11750,10010264,48,2452,24,1489,0.464480823,1.214425316,0.725918092,2.082186341,0.631531842,DB1175010010264_,0.459606915,0.194270974,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,clobetasol,DB11750
,176567,DB01592,10033775,53,6223,26,3041,1,0.996137558,0.610561677,1.663008727,1,DB0159210033775_,0,-0.003869921,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,iron,DB01592
,176571,DB00480,10061161,76,67352,26,67636,4.70335727697104e-07,2.935542702,1.858355567,4.776032373,7.34567712567937e-06,DB0048010061161_,11.82139856,1.076892343,female,10061161,Pelvic fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,176573,DB00381,10015929,42,29318,12,22875,0.001380873,2.730728358,1.410975566,5.698694833,0.007182399,DB0038110015929_,4.936121858,1.004568372,female,10015929,Eye infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,176575,DB00264,10001488,25,29582,50,24842,0.000283891,0.419888299,0.248822299,0.691915111,0.001928954,DB0026410001488_,6.250777208,-0.867766558,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,176579,DB00193,10049414,40,19280,18,8684,1,1.000922077,0.560402719,1.855909245,1,DB0019310049414_,0,0.000921652,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,176585,DB00364,10053762,75,2675,40,1360,0.841585641,0.953282509,0.637207352,1.444674466,0.919202949,DB0036410053762_,0.084248345,-0.047843978,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sucralfate,DB00364
,176586,DB00804,10053762,124,2876,26,873,0.09335142,1.447526259,0.935221851,2.318411367,0.200706198,DB0080410053762_,1.605913141,0.369856071,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,dicyclomine,DB00804
,176599,DB01076,10003827,46,25701,20,25563,0.001852354,2.287758827,1.326013038,4.083473669,0.009136636,DB0107610003827_,4.695462967,0.82757266,NA,10003827,Autoimmune hepatitis,10019805,Hepatobiliary disorders,Hepat,atorvastatin,DB01076
,176634,DB00047,10019974,36,9249,19,8499,0.057742889,1.741033104,0.971695626,3.215982665,0.139225963,DB0004710019974_,1.97165703,0.554478675,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,176642,DB01611,10019974,121,11792,13,2348,0.034626732,1.853252556,1.041652008,3.587263527,0.0946805,DB0161110019974_,2.357247212,0.616942234,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,hydroxychloroquine,DB01611
,176645,DB05259,10010774,41,11229,19,2709,0.021898265,0.520647536,0.294859911,0.951322844,0.066389943,DB0525910010774_,2.712209692,-0.652681981,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,glatiramer,DB05259
,176681,DB00333,10007515,120,2951,135,3017,0.481927781,0.90879244,0.700853118,1.177288445,0.646365533,DB0033310007515_,0.436390095,-0.09563855,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,methadone,DB00333
,176686,DB08931,10021143,143,6434,41,2405,0.154143579,1.303665174,0.912271246,1.899003511,0.289714979,DB0893110021143_,1.238857669,0.265179662,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,176687,DB08931,10038695,114,6463,44,2402,0.856740071,0.962923999,0.672089536,1.401040712,0.931227655,DB0893110038695_,0.071251504,-0.037780791,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,176702,DB00065,10025482,182,9282,70,4887,0.02713878,1.368879193,1.031192924,1.83425293,0.078316168,DB0006510025482_,2.547001205,0.313992298,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,176712,DB01015,10068319,45,9842,41,9340,0.914030003,1.041587439,0.666236596,1.632488344,0.961536643,DB0101510068319_,0.039222604,0.040745933,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,176714,DB01136,10065154,75,9809,73,11042,0.408823387,1.156532424,0.825637052,1.620763932,0.578204075,DB0113610065154_,0.547828401,0.145426238,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,carvedilol,DB01136
,176734,DB06228,10054787,75,15837,70,16006,0.677492052,1.082833014,0.770708114,1.523048103,0.80448507,DB0622810054787_,0.217552871,0.079580767,NA,10054787,Haemorrhoidal haemorrhage,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,176736,DB01075,10001949,40,19908,25,11072,0.69783474,0.889860141,0.526454777,1.531320963,0.818262715,DB0107510001949_,0.200571827,-0.116690973,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,176738,DB01233,10012378,57,3364,15,1711,0.02311717,1.93254018,1.075710573,3.686618269,0.069190834,DB0123310012378_,2.670886884,0.658835293,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,metoclopramide,DB01233
,176746,DB01233,10020751,49,3372,17,1709,0.191691906,1.460736129,0.823673308,2.714085042,0.338753647,DB0123310020751_,1.082482141,0.378940506,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,metoclopramide,DB01233
,176817,DB00321,10014387,42,7405,24,2826,0.128388246,0.667888051,0.394384757,1.155352459,0.253357493,DB0032110014387_,1.372953773,-0.403634707,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,amitriptyline,DB00321
,176818,DB00836,10014387,119,5416,161,3914,2.93617308783388e-07,0.534197804,0.416349055,0.683789943,4.80406533543191e-06,DB0083610014387_,12.24604805,-0.62698909,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,loperamide,DB00836
,176819,DB00836,10047302,79,5456,125,3950,5.58343310152098e-08,0.457584541,0.339703992,0.613272146,1.06890414474493e-06,DB0083610047302_,13.7488766,-0.781793622,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,loperamide,DB00836
,176820,DB00836,10074903,70,5465,68,4007,0.118064232,0.754807241,0.531417443,1.072565115,0.238286048,DB0083610074903_,1.434283444,-0.281292873,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,loperamide,DB00836
,176821,DB00321,10013654,198,7249,132,2718,9.24361023201014e-07,0.562475279,0.446919022,0.709646879,1.33719479883537e-05,DB0032110013654_,11.22235148,-0.575408094,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,amitriptyline,DB00321
,176822,DB00836,10013654,200,5335,345,3730,6.12284627206327e-24,0.405344764,0.337098181,0.486403158,8.77051848834785e-22,DB0083610013654_,48.48547612,-0.903017305,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,loperamide,DB00836
,176824,DB00836,10044066,70,5465,108,3967,1.0913417463717e-06,0.470517758,0.342230036,0.643410577,1.54516120675358e-05,DB0083610044066_,11.07779722,-0.753921577,NA,10044066,Torsade de pointes,10007541,Cardiac disorders,Card,loperamide,DB00836
,176827,DB09140,10054112,119,3622,35,1763,0.008681453,1.654804947,1.121320708,2.497546963,0.03180598,DB0914010054112_,3.448100956,0.503683145,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,oxygen,DB09140
,176833,DB01225,10021015,56,4988,34,4606,0.056581723,1.520850347,0.973860549,2.40690731,0.137086422,DB0122510021015_,1.987143737,0.419269617,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,enoxaparin,DB01225
,176845,DB01156,10007882,60,13562,32,6296,0.574577846,0.870461636,0.557072051,1.383271966,0.724319154,DB0115610007882_,0.322523163,-0.138731592,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,bupropion,DB01156
,176873,DB00472,10069327,47,10712,17,4295,0.782938223,1.108505566,0.623991253,2.061717409,0.881806742,DB0047210069327_,0.12578236,0.103012771,NA,10069327,Product quality issue,10077536,Product issues,Prod,fluoxetine,DB00472
,176880,DB01377,10051398,37,3759,27,2643,0.898980553,0.963508726,0.569420245,1.649849487,0.956490275,DB0137710051398_,0.044484657,-0.037173735,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,magnesium oxide,DB01377
,176891,DB00046,10020642,38,5421,31,4661,0.903747823,1.053961999,0.637435377,1.754817719,0.957417047,DB0004610020642_,0.043516196,0.052556396,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,insulin lispro,DB00046
,176895,DB00046,10020937,43,5416,22,4670,0.046367428,1.685237594,0.984403597,2.962962603,0.118221285,DB0004610020937_,2.135197113,0.521906559,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,insulin lispro,DB00046
,176902,DB00421,10029331,72,8831,49,5203,0.450388942,0.865739508,0.592894081,1.273370121,0.618100211,DB0042110029331_,0.48110468,-0.144171215,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,176904,DB01307,10029331,34,2490,29,2040,0.899034726,0.960522258,0.565815207,1.640392377,0.956490275,DB0130710029331_,0.044484657,-0.040278124,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,insulin detemir,DB01307
,176935,DB00115,10044034,83,18342,32,10440,0.06471548,1.476305773,0.970259627,2.296405543,0.151950161,DB0011510044034_,1.884202698,0.389542868,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,176936,DB14513,10044034,38,7139,16,3548,0.664761422,1.180313362,0.641631918,2.270724146,0.795939233,DB1451310044034_,0.228232437,0.165779964,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,176939,DB00476,10053425,79,17178,7,6170,3.68839152344394e-05,4.053586319,1.876633407,10.41592772,0.000340173,DB0047610053425_,7.986055563,1.399602,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,176969,DB00915,10010305,45,1410,56,995,0.005431731,0.567205313,0.371067317,0.862766967,0.02185079,DB0091510010305_,3.823518225,-0.567033936,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,amantadine,DB00915
,176972,DB00126,10012374,39,10132,19,5926,0.586493246,1.200569512,0.676515897,2.201721813,0.733692262,DB0012610012374_,0.3096656,0.182796038,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,ascorbic acid,DB00126
,177018,DB00115,10022998,48,18377,26,10446,0.903992358,1.049407015,0.637713413,1.763275226,0.957450283,DB0011510022998_,0.043481484,0.048225257,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,177023,DB00904,10022998,47,23022,32,14424,0.729385545,0.92022068,0.5746205,1.490968684,0.842332069,DB0090410022998_,0.171580962,-0.083141769,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,177033,DB00285,10041466,39,10912,11,3707,0.74458765,1.204433749,0.604157499,2.610296136,0.854143649,DB0028510041466_,0.157655892,0.186009539,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,177058,DB00285,10057668,53,10898,20,3698,0.686397895,0.899215038,0.527831549,1.590231597,0.810802116,DB0028510057668_,0.209731255,-0.106233077,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,177073,DB00863,10013911,53,10620,28,5812,0.907942616,1.035902056,0.642738894,1.702968975,0.958771936,DB0086310013911_,0.042102046,0.035272599,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,177075,DB00863,10040844,34,10639,27,5813,0.179010193,0.688027919,0.402523893,1.186966064,0.322677474,DB0086310040844_,1.131101987,-0.373925862,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,177094,DB00364,10000087,80,2670,29,1371,0.123616236,1.416393212,0.910534426,2.259032275,0.246557102,DB0036410000087_,1.400161661,0.348113649,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,sucralfate,DB00364
,177099,DB01296,10003988,41,1408,15,968,0.038610154,1.878709453,1.011344653,3.6754354,0.102846265,DB0129610003988_,2.274519982,0.63058508,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,glucosamine,DB01296
,177102,DB00768,10016256,78,1837,20,664,0.198819707,1.409467402,0.845647301,2.452823011,0.347622043,DB0076810016256_,1.056639472,0.343211904,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,olopatadine,DB00768
,177120,DB08895,10036018,96,28018,12,6634,0.036360756,1.89415834,1.035104092,3.796201429,0.098281914,DB0889510036018_,2.319915261,0.638774592,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,tofacitinib,DB08895
,177133,DB00364,10048959,59,2691,18,1382,0.052361563,1.683155458,0.974427648,3.044957334,0.129463237,DB0036410048959_,2.044358321,0.52067028,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sucralfate,DB00364
,177135,DB00158,10056819,55,16760,19,8085,0.262953984,1.396419177,0.8152485,2.493246207,0.424738016,DB0015810056819_,0.856282733,0.333911229,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,177139,DB00588,10056819,60,16464,26,8442,0.496339644,1.183254462,0.734707992,1.955220629,0.658567276,DB0058810056819_,0.417688598,0.168268661,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,177165,DB05679,10006451,41,6890,10,4899,0.001471482,2.914954583,1.434227638,6.531908523,0.007569063,DB0567910006451_,4.883686041,1.069854239,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,ustekinumab,DB05679
,177167,DB00575,10028334,70,5174,39,3790,0.204477578,1.314719533,0.874243338,2.002750659,0.354472754,DB0057510028334_,1.037123794,0.27362336,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,clonidine,DB00575
,177168,DB00669,10028334,80,6297,11,1086,0.553464621,1.254241103,0.661938699,2.62171271,0.707011279,DB0066910028334_,0.346708661,0.226530691,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,sumatriptan,DB00669
,177233,DB00455,10021036,43,9358,12,5106,0.046597766,1.955090646,1.011692479,4.077159257,0.11868433,DB0045510021036_,2.131287998,0.670436558,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,loratadine,DB00455
,177238,DB00927,10021036,46,7451,24,4992,0.392056962,1.284097471,0.766606731,2.202504909,0.561959715,DB0092710021036_,0.576325114,0.250056114,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,famotidine,DB00927
,177240,DB01225,10021036,45,4999,29,4611,0.160630213,1.431229431,0.876269324,2.371513155,0.29838623,DB0122510021036_,1.209366558,0.358533817,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,enoxaparin,DB01225
,177268,DB00572,10022437,50,2852,21,2105,0.029614318,1.757136591,1.032626329,3.090146938,0.08385805,DB0057210022437_,2.47862979,0.563685547,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,atropine,DB00572
,177282,DB00480,10047531,34,67394,25,67637,0.244181233,1.364895368,0.790631779,2.386655223,0.402719977,DB0048010047531_,0.909513805,0.311077773,NA,10047531,Visual acuity reduced,10015919,Eye disorders,Eye,lenalidomide,DB00480
,177298,DB00264,10033647,38,29569,27,24865,0.535218677,1.183504989,0.703633162,2.016250143,0.69177208,DB0026410033647_,0.368498741,0.168480366,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,177299,DB00904,10033647,30,23039,20,14436,0.884650343,0.939886566,0.516162877,1.746823114,0.951939928,DB0090410033647_,0.049253347,-0.061996085,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,177325,DB00678,10027175,190,15409,78,10646,7.85816971501237e-05,1.682913936,1.284836855,2.222365994,0.00064882,DB0067810027175_,7.340354533,0.520526777,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,losartan,DB00678
,177327,DB01039,10027175,36,2937,25,3026,0.156454001,1.483531202,0.863846674,2.585223601,0.292665796,DB0103910027175_,1.22872395,0.394425194,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,fenofibrate,DB01039
,177334,DB06218,10035664,35,1659,18,1418,0.094821848,1.661713516,0.911337424,3.131179807,0.202955276,DB0621810035664_,1.59476964,0.507849308,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,lacosamide,DB06218
,177335,DB00186,10038683,37,16864,20,9988,0.785446271,1.095703878,0.61928934,1.993548168,0.883669115,DB0018610038683_,0.12367259,0.091396968,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,177362,DB00443,10011224,41,2105,18,1172,0.493201024,1.26813681,0.708650509,2.356542727,0.655979199,DB0044310011224_,0.421626199,0.237548744,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,betamethasone,DB00443
,177363,DB00443,10016256,95,2051,51,1139,0.929635562,1.034446216,0.722514089,1.495560735,0.971029456,DB0044310016256_,0.029398475,0.033866227,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,betamethasone,DB00443
,177366,DB00443,10035664,51,2095,29,1161,0.906447207,0.974577254,0.602303567,1.604162335,0.958224861,DB0044310035664_,0.042672809,-0.025751488,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,betamethasone,DB00443
,177375,DB00820,10061428,401,11514,109,5707,1.0285512311238e-08,1.823417817,1.468257006,2.280286483,2.3077651822526e-07,DB0082010061428_,15.28181605,0.600712661,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,tadalafil,DB00820
,177377,DB08893,10019211,96,1989,22,1036,0.00031593,2.272353608,1.408243984,3.817956717,0.002105266,DB0889310019211_,6.163313606,0.820816126,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,mirabegron,DB08893
,177378,DB08931,10002855,133,6444,26,2420,0.001566747,1.920941616,1.250881358,3.056169866,0.007965347,DB0893110002855_,4.83265481,0.652815491,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,riociguat,DB08931
,177379,DB08931,10003239,278,6299,77,2369,0.020468577,1.357749874,1.046352777,1.77921279,0.062929593,DB0893110003239_,2.765738751,0.305828825,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,riociguat,DB08931
,177382,DB08931,10013709,88,6489,33,2413,1,0.99162767,0.655729832,1.532122768,1,DB0893110013709_,0,-0.008407575,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,177385,DB08931,10033433,376,6201,103,2343,0.004303216,1.379203993,1.100175149,1.741479437,0.018126607,DB0893110033433_,4.010374407,0.321506516,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,riociguat,DB08931
,177390,DB08931,10052264,70,6507,8,2438,0.000452704,3.278297172,1.572201117,7.903411331,0.002843326,DB0893110052264_,5.862780907,1.187324133,female,10052264,Catheter site erythema,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,177391,DB08931,10052268,57,6520,12,2434,0.076779326,1.773189106,0.938673597,3.637378591,0.172831231,DB0893110052268_,1.755439702,0.57277968,NA,10052268,Catheter site pain,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,177392,DB08931,10052270,54,6523,7,2439,0.005436253,2.884399251,1.30599322,7.523941262,0.021867307,DB0893110052270_,3.822762581,1.059316646,female,10052270,Catheter site pruritus,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,177397,DB08931,10054236,69,6508,12,2434,0.011604343,2.150380727,1.153119782,4.370000284,0.0400973,DB0893110054236_,3.216446273,0.765644909,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,riociguat,DB08931
,177404,DB01240,10073989,58,5693,9,1567,0.133895717,1.773677302,0.870319086,4.081458018,0.261164213,DB0124010073989_,1.342605902,0.573054963,NA,10073989,Catheter site vesicles,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,177446,DB00982,10001551,35,3329,52,2049,5.34248388192031e-05,0.414345643,0.260987785,0.650818133,0.000467079,DB0098210001551_,7.669012951,-0.881054768,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,isotretinoin,DB00982
,177447,DB00982,10003481,29,3335,54,2047,1.01854153125141e-06,0.329698493,0.201710832,0.529032493,1.45377123288971e-05,DB0098210003481_,11.13876443,-1.109576701,male,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,isotretinoin,DB00982
,177451,DB01097,10024384,54,6211,13,1490,1,0.996495462,0.534971566,1.995820284,1,DB0109710024384_,0,-0.003510693,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,leflunomide,DB01097
,177452,DB08895,10015916,65,28049,9,6637,0.140270106,1.708895002,0.846406888,3.905791907,0.270228652,DB0889510015916_,1.30848682,0.535846964,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,tofacitinib,DB08895
,177454,DB00480,10064355,45,67383,35,67627,0.265499041,1.290364018,0.811119378,2.068078116,0.427521199,DB0048010064355_,0.849751403,0.254924363,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,177490,DB00051,10022081,57,25674,13,11407,0.027263061,1.94806132,1.053078279,3.880986833,0.078578187,DB0005110022081_,2.543661137,0.666834683,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,177491,DB00982,10001760,56,3308,18,2083,0.011417661,1.958799348,1.130662188,3.550891265,0.03958494,DB0098210001760_,3.229306534,0.672331708,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,isotretinoin,DB00982
,177509,DB00982,10028813,78,3286,31,2070,0.036251274,1.58489665,1.028841222,2.49631092,0.09803477,DB0098210028813_,2.322433064,0.4605192,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,isotretinoin,DB00982
,177518,DB00051,10044390,37,25694,27,11393,0.056890097,0.607646084,0.359909767,1.038245867,0.137598915,DB0005110044390_,1.983412238,-0.498162666,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,177519,DB00005,10054889,58,128024,21,42398,0.697703903,0.914657086,0.546717932,1.586851746,0.818237054,DB0000510054889_,0.200603187,-0.089206053,NA,10054889,Transaminases increased,10022891,Investigations,Inv,etanercept,DB00005
,177528,DB00213,10068319,121,18774,52,13369,0.001940448,1.656977596,1.186849752,2.341507814,0.009498962,DB0021310068319_,4.656572796,0.504995217,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,177553,DB06403,10027175,92,21379,18,6643,0.072581585,1.588089672,0.95032299,2.799817243,0.16581182,DB0640310027175_,1.796901747,0.46253183,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,177558,DB00005,10074903,1333,126749,775,41644,4.18846245723294e-34,0.565121694,0.516477756,0.618661863,1.20321022610238e-31,DB0000510074903_,71.19514471,-0.570714183,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,177560,DB00246,10010264,35,1039,26,675,0.689553151,0.87461635,0.506433065,1.527940335,0.812875364,DB0024610010264_,0.207177486,-0.133969946,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ziprasidone,DB00246
,177563,DB00186,10012239,36,16865,22,9986,0.892715579,0.968892648,0.554374532,1.729918594,0.9552998,DB0018610012239_,0.045730061,-0.03160146,NA,10012239,Delusion,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,177584,DB00186,10043414,36,16865,29,9979,0.247345837,0.734550967,0.437642463,1.24277264,0.406571529,DB0018610043414_,0.899995403,-0.308495895,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,177590,DB09153,10008469,110,7689,51,5648,0.006289885,1.584282428,1.124565033,2.257976334,0.024593473,DB0915310008469_,3.70527421,0.460131578,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,177647,DB00480,10022000,752,66676,786,66876,0.426686179,0.959601506,0.866670086,1.06252206,0.595394501,DB0048010022000_,0.518531067,-0.041237178,NA,10022000,Influenza,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,177648,DB00814,10022000,100,8187,29,3386,0.098101508,1.42616082,0.933068881,2.241682849,0.207985009,DB0081410022000_,1.570289275,0.354986093,NA,10022000,Influenza,10021881,Infections and infestations,Infec,meloxicam,DB00814
,177649,DB00924,10022000,113,10049,34,4217,0.101414517,1.394725084,0.941305025,2.114905905,0.212998847,DB0092410022000_,1.546468526,0.332697324,NA,10022000,Influenza,10021881,Infections and infestations,Infec,cyclobenzaprine,DB00924
,177674,DB00879,10000059,6,1771,61,3651,8.98715468302413e-06,0.202794291,0.071494684,0.468661598,9.89641226825678e-05,DB0087910000059_,9.220753171,-1.595563158,male,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,emtricitabine,DB00879
,177689,DB00115,10013774,69,18356,16,10456,0.000622068,2.456429981,1.410003401,4.53693918,0.003712772,DB0011510013774_,5.595976583,0.898709068,NA,10013774,Dry eye,10015919,Eye disorders,Eye,cyanocobalamin,DB00115
,177694,DB00115,10023644,44,18381,17,10455,0.184930774,1.472153499,0.823825539,2.749766996,0.330056383,DB0011510023644_,1.108491781,0.386726294,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,cyanocobalamin,DB00115
,177698,DB01076,10023644,47,25700,34,25549,0.181912496,1.374217281,0.865004997,2.204129214,0.326309069,DB0107610023644_,1.119910281,0.317884319,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,atorvastatin,DB01076
,177708,DB01076,10052140,36,25711,18,25565,0.019803791,1.988606295,1.099789498,3.720788144,0.061315012,DB0107610052140_,2.791730565,0.687434039,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,atorvastatin,DB01076
,177739,DB01075,10028347,35,19913,20,11077,1,0.973454747,0.546347651,1.780516252,1,DB0107510028347_,0,-0.02690394,NA,10028347,Muscle twitching,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,177741,DB00377,10051792,56,1063,15,708,0.001178069,2.485451109,1.373377752,4.770540252,0.006305988,DB0037710051792_,5.066255671,0.910454176,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,palonosetron,DB00377
,177746,DB00476,10001488,101,17156,45,6132,0.22124583,0.802214002,0.558519071,1.168208459,0.375081211,DB0047610001488_,0.980612714,-0.220379871,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,177760,DB00582,10035664,46,1084,93,1481,0.03413994,0.675868218,0.459894063,0.981589489,0.093685684,DB0058210035664_,2.367809888,-0.391757166,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,voriconazole,DB00582
,177764,DB00051,10018884,56,25675,43,11377,0.008494359,0.577088835,0.380681534,0.88025166,0.031249017,DB0005110018884_,3.465767344,-0.549759065,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,adalimumab,DB00051
,177766,DB00331,10023126,25,24921,35,20717,0.051259964,0.593805364,0.340544053,1.021208473,0.127379187,DB0033110023126_,2.06058692,-0.521203683,NA,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,metformin,DB00331
,177801,DB00695,10061481,46,28003,28,20500,0.481101342,1.202666585,0.735688977,1.998750784,0.645738402,DB0069510061481_,0.437360807,0.184541246,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,177812,DB00451,10067125,42,47229,8,15411,0.189314122,1.713016266,0.79429963,4.225513129,0.335702739,DB0045110067125_,1.091529215,0.538255715,NA,10067125,Liver injury,10019805,Hepatobiliary disorders,Hepat,levothyroxine,DB00451
,177821,DB00169,10040880,38,38653,26,18149,0.141492419,0.68623855,0.405783642,1.177512149,0.271924745,DB0016910040880_,1.302229925,-0.376529971,NA,10040880,Skin irritation,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,177833,DB06285,10013709,91,8759,15,1091,0.348668765,0.755674827,0.432996471,1.410500935,0.518170934,DB0628510013709_,0.657450103,-0.280144118,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,177837,DB00175,10006451,96,8035,49,6057,0.028149468,1.476844482,1.034467797,2.131871912,0.08057814,DB0017510006451_,2.518527883,0.389907705,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,pravastatin,DB00175
,177846,DB00695,10021114,70,27979,25,20503,0.00167898,2.051794936,1.282571912,3.382871569,0.00842696,DB0069510021114_,4.776319224,0.718714989,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,furosemide,DB00695
,177874,DB01221,10013654,21,510,37,559,0.104768885,0.622357208,0.341266716,1.10799845,0.218152664,DB0122110013654_,1.522560167,-0.474241062,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,ketamine,DB01221
,177903,DB00175,10006784,33,8098,20,6086,0.489077352,1.240027856,0.690001247,2.282822709,0.652475482,DB0017510006784_,0.426981715,0.215133844,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,177905,DB00295,10006784,52,14611,15,9587,0.003762346,2.274572793,1.260215586,4.352807972,0.016234633,DB0029510006784_,4.120608476,0.821792251,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,morphine,DB00295
,177908,DB00761,10006784,74,15233,15,8610,8.94399067179774e-05,2.788311426,1.58505726,5.235110405,0.000725931,DB0076110006784_,7.228055417,1.025436189,female,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,177912,DB00852,10019211,84,1082,15,456,0.001818185,2.359047074,1.334249467,4.44985258,0.008995952,DB0085210019211_,4.710980586,0.858257755,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pseudoephedrine,DB00852
,177920,DB00482,10028372,71,8188,22,3049,0.484757271,1.201726557,0.734448785,2.040472576,0.648902264,DB0048210028372_,0.432473168,0.18375932,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,177922,DB00668,10028372,51,10040,28,4275,0.270463761,0.775549591,0.479201003,1.279252406,0.433167193,DB0066810028372_,0.836631499,-0.254183351,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,epinephrine,DB00668
,177925,DB01060,10028372,54,8533,20,5061,0.071500338,1.601342366,0.941724108,2.82777677,0.16388092,DB0106010028372_,1.808615211,0.470842256,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,amoxicillin,DB01060
,177927,DB09153,10028372,32,7767,48,5651,0.001412033,0.485063783,0.299703436,0.775669807,0.007309038,DB0915310028372_,4.91864366,-0.723474886,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium chloride,DB09153
,177933,DB00404,10061224,49,19843,20,9842,0.523181035,1.215151356,0.70864315,2.159530086,0.681565552,DB0040410061224_,0.383362844,0.194868642,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,177935,DB00497,10061224,40,19227,33,16342,1,1.030246627,0.633175103,1.686830862,1,DB0049710061224_,0,0.029798218,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,177942,DB01075,10061224,45,19903,11,11086,0.011578262,2.278587292,1.159728567,4.88779134,0.040036126,DB0107510061224_,3.21797307,0.823555642,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,177948,DB01255,10037844,39,2094,17,1561,0.076067219,1.709939622,0.94079358,3.236349007,0.171587802,DB0125510037844_,1.76266018,0.536458061,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,lisdexamfetamine,DB01255
,177978,DB11133,10003239,81,2350,33,1541,0.02486871,1.609372847,1.055305264,2.504218017,0.073209627,DB1113310003239_,2.614428353,0.475844567,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,omega-3 fatty acids,DB11133
,177985,DB01136,10022000,105,9779,93,11022,0.099831537,1.272522718,0.952092857,1.703089552,0.210515198,DB0113610022000_,1.55819743,0.241001322,NA,10022000,Influenza,10021881,Infections and infestations,Infec,carvedilol,DB01136
,177991,DB00343,10040753,119,8617,23,5072,9.37461641073411e-08,3.045173111,1.933692694,4.995331625,1.7052719194197e-06,DB0034310040753_,13.28178598,1.11355775,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,diltiazem,DB00343
,177992,DB00557,10040753,86,5901,15,3052,1.90196294683492e-05,2.964994404,1.697831271,5.536691866,0.000191142,DB0055710040753_,8.562495832,1.086875145,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,hydroxyzine,DB00557
,178007,DB00829,10023232,56,7996,16,4438,0.018520437,1.942502959,1.097002872,3.632357958,0.05815083,DB0082910023232_,2.844715119,0.663977327,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,diazepam,DB00829
,178008,DB01060,10023232,57,8530,22,5059,0.101634356,1.536578852,0.92344199,2.643167113,0.213349762,DB0106010023232_,1.544822386,0.42955842,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,amoxicillin,DB01060
,178010,DB00741,10039101,36,4058,17,3157,0.096059275,1.647353761,0.899709792,3.133777072,0.204861351,DB0074110039101_,1.585421865,0.499170219,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrocortisone,DB00741
,178011,DB00788,10040753,160,9196,43,5018,1.57555591189723e-05,2.03031772,1.439094361,2.918688982,0.000161708,DB0078810040753_,8.729716668,0.708192293,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,naproxen,DB00788
,178012,DB00158,10062244,40,16775,12,8092,0.181823738,1.60792025,0.826442658,3.369008443,0.326216037,DB0015810062244_,1.120195426,0.474941574,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,178018,DB08895,10062244,134,27980,18,6628,0.022443668,1.763422282,1.073192583,3.068600333,0.067607372,DB0889510062244_,2.694038253,0.567256399,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,178029,DB00542,10019211,86,1600,36,1388,0.000196973,2.071837002,1.378551287,3.169870479,0.001422765,DB0054210019211_,6.555152976,0.728435654,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,benazepril,DB00542
,178030,DB08910,10005728,27,16717,32,17456,0.696376899,0.881052915,0.507577026,1.51871275,0.817351734,DB0891010005728_,0.201685758,-0.126637592,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,pomalidomide,DB08910
,178035,DB00374,10017367,42,17674,18,5706,0.296322504,0.75331985,0.423949282,1.391549945,0.462190661,DB0037410017367_,0.771777788,-0.283265373,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,178047,DB08932,10012378,169,19274,55,6542,0.817468109,1.042976159,0.764035676,1.442868911,0.90244222,DB0893210012378_,0.102650613,0.042078318,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,macitentan,DB08932
,178053,DB00480,10014020,76,67352,21,67641,1.02243272456015e-08,3.634222416,2.217467624,6.207215028,2.29796016802595e-07,DB0048010014020_,15.28607381,1.290395172,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,lenalidomide,DB00480
,178055,DB01234,10014020,49,31576,14,32874,3.49512397364775e-06,3.643405008,1.979188758,7.148210471,4.31716793455503e-05,DB0123410014020_,10.05032585,1.292918686,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,dexamethasone,DB01234
,178064,DB00635,10064658,52,33001,21,23773,0.024018621,1.78375446,1.055669655,3.118731331,0.071283818,DB0063510064658_,2.64108594,0.57872039,NA,10064658,Osteonecrosis of jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,178073,DB05676,10028372,69,47060,30,25299,0.345076407,1.236412099,0.794335133,1.967249758,0.514526668,DB0567610028372_,0.664507893,0.212213717,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,178094,DB00758,10008469,63,8237,59,10015,0.17080702,1.298259388,0.894510814,1.886532872,0.311934385,DB0075810008469_,1.164962416,0.261024435,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,178122,DB00555,10020751,46,7001,15,3471,0.173817933,1.520355383,0.832177993,2.936102056,0.31591487,DB0055510020751_,1.152282501,0.418944112,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,lamotrigine,DB00555
,178130,DB00555,10033775,61,6986,31,3455,0.911615744,0.973147325,0.620380793,1.55471544,0.960355089,DB0055510033775_,0.040452178,-0.027219795,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,178137,DB00404,10039897,36,19856,28,9834,0.083384203,0.636765981,0.377578418,1.084053299,0.184103228,DB0040410039897_,1.692258659,-0.451353068,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,178139,DB00555,10040753,72,6975,15,3471,0.001239538,2.388479399,1.354048946,4.493394887,0.006566815,DB0055510040753_,5.025726416,0.870656929,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,lamotrigine,DB00555
,178144,DB00555,10068319,39,7008,12,3474,0.179147989,1.611020589,0.825125048,3.383917547,0.32281517,DB0055510068319_,1.130675349,0.476867884,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lamotrigine,DB00555
,178153,DB05676,10013781,79,47050,27,25302,0.041530001,1.573460783,1.00477559,2.535107307,0.108807982,DB0567610013781_,2.218170588,0.453277514,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,178163,DB08895,10028997,48,28066,26,6620,0.001015279,0.43546871,0.264589395,0.731797032,0.00557448,DB0889510028997_,5.189556263,-0.831332333,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,tofacitinib,DB08895
,178179,DB00958,10016825,51,4543,26,2559,0.721719401,1.104901537,0.674270864,1.850949208,0.836020471,DB0095810016825_,0.179102179,0.099756225,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,carboplatin,DB00958
,178182,DB00758,10018985,50,8250,70,10004,0.462616014,0.866157058,0.589442108,1.264627988,0.629848852,DB0075810018985_,0.462275406,-0.143689027,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,178187,DB01296,10013573,51,1398,33,950,0.910034263,1.050187275,0.659119489,1.693664656,0.959542868,DB0129610013573_,0.041298287,0.048968505,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,glucosamine,DB01296
,178190,DB00390,10050584,45,4100,21,3280,0.045973828,1.71416385,0.997810256,3.036004714,0.11743084,DB0039010050584_,2.141905713,0.538925411,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,digoxin,DB00390
,178209,DB00706,10005750,13,1062,126,15799,0.157495893,1.534824321,0.792507367,2.732524976,0.294183061,DB0070610005750_,1.223553048,0.428415926,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,tamsulosin,DB00706
,178227,DB00178,10053762,40,1397,36,1644,0.294409474,1.307442837,0.807495882,2.12377567,0.460271994,DB0017810053762_,0.775937673,0.268073196,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ramipril,DB00178
,178232,DB00321,10040753,108,7339,17,2833,0.000254803,2.452105571,1.45933797,4.371976921,0.001764354,DB0032110040753_,6.339970861,0.896947072,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,amitriptyline,DB00321
,178239,DB05676,10040753,453,46676,148,25181,5.48597486880783e-08,1.65125024,1.367719299,2.002981167,1.05254634617966e-06,DB0567610040753_,13.76429824,0.501532722,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,apremilast,DB05676
,178243,DB00673,10011906,82,585,61,280,0.017265791,0.643683497,0.442141203,0.940615894,0.055064017,DB0067310011906_,2.89925882,-0.440548137,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,aprepitant,DB00673
,178247,DB00227,10022437,44,2423,33,1770,0.907883114,0.973994854,0.603422235,1.585933484,0.958771936,DB0022710022437_,0.042102046,-0.026349259,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,lovastatin,DB00227
,178262,DB00863,10028810,165,10508,57,5783,0.002304086,1.593054847,1.169955571,2.196346647,0.010913219,DB0086310028810_,4.517780468,0.465653461,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ranitidine,DB00863
,178264,DB00321,10033557,56,7391,12,2838,0.076115242,1.791854052,0.947627842,3.678308266,0.171688762,DB0032110033557_,1.762071965,0.583250867,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,amitriptyline,DB00321
,178265,DB00863,10033557,108,10565,18,5822,1.60744508747026e-07,3.306194588,1.993448703,5.794971661,2.79257727192041e-06,DB0086310033557_,12.78854564,1.195797857,female,10033557,Palpitations,10007541,Cardiac disorders,Card,ranitidine,DB00863
,178267,DB00863,10046306,103,10570,39,5801,0.052245722,1.449409976,0.992106797,2.155762027,0.12924977,DB0086310046306_,2.046008545,0.37115656,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,ranitidine,DB00863
,178289,DB00820,10036653,139,11776,34,5782,0.00016362,2.007248677,1.369171353,3.017542942,0.001214901,DB0082010036653_,6.713092753,0.696764967,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,178291,DB08932,10042772,595,18848,209,6388,0.650754354,0.964872756,0.820635908,1.137990993,0.785255844,DB0893210042772_,0.241745698,-0.035759045,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,178297,DB04868,10001760,66,1575,15,1501,2.83478891018771e-08,4.191379501,2.354278324,7.944616481,5.74941562533056e-07,DB0486810001760_,14.36899743,1.433029916,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,nilotinib,DB04868
,178301,DB00950,10003988,80,4638,46,2010,0.142122422,0.753712232,0.51593382,1.112467683,0.272757583,DB0095010003988_,1.299171852,-0.282744639,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fexofenadine,DB00950
,178304,DB00126,10013950,63,10108,33,5912,0.671779807,1.11660506,0.720653788,1.75903822,0.800822342,DB0012610013950_,0.222116152,0.110292885,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,178306,DB00043,10013952,46,6367,14,2286,0.661168079,1.179672335,0.635781728,2.328150409,0.79329908,DB0004310013952_,0.231554978,0.165236718,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omalizumab,DB00043
,178310,DB14513,10013952,49,7128,7,3557,0.000546529,3.492777956,1.571608381,9.149172779,0.003321508,DB1451310013952_,5.707336494,1.250697396,female,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium,DB14513
,178332,DB00950,10021097,53,4665,29,2027,0.33428923,0.794166765,0.494193365,1.299486229,0.503386436,DB0095010021097_,0.686397142,-0.230461809,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,fexofenadine,DB00950
,178345,DB00455,10028372,78,9323,34,5084,0.320815004,1.251047186,0.824881781,1.933581695,0.489088675,DB0045510028372_,0.715211467,0.223980949,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,178346,DB00950,10028372,37,4681,17,2039,0.882130862,0.948058694,0.51922632,1.799896027,0.950746667,DB0095010028372_,0.050507638,-0.053338865,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,fexofenadine,DB00950
,178352,DB00996,10030041,48,38905,22,22403,0.456315252,1.256401583,0.743639663,2.186098376,0.623693329,DB0099610030041_,0.472096491,0.228251748,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,gabapentin,DB00996
,178372,DB13961,10036790,40,9417,28,6386,0.901997087,0.968749553,0.582279633,1.632354075,0.957184982,DB1396110036790_,0.043758612,-0.031749159,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,178374,DB00950,10037660,101,4617,47,2009,0.71797584,0.935079754,0.652414066,1.357072354,0.833478562,DB0095010037660_,0.182147298,-0.067123455,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,178376,DB00341,10040047,80,11325,59,5009,0.004032878,0.599743366,0.422384452,0.855825767,0.017195912,DB0034110040047_,4.063083597,-0.511253439,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,cetirizine,DB00341
,178377,DB00471,10040047,102,14087,56,5409,0.039832181,0.699389602,0.499198776,0.988603338,0.105350366,DB0047110040047_,2.250463667,-0.357547322,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,montelukast,DB00471
,178381,DB00588,10040070,37,16487,19,8449,1,0.997956874,0.559009842,1.838319515,1,DB0058810040070_,0,-0.002045217,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,178382,DB00641,10040070,24,14100,35,12440,0.066889888,0.605002469,0.3440949,1.04709203,0.155735434,DB0064110040070_,1.859596647,-0.502522741,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,simvastatin,DB00641
,178383,DB00863,10040070,31,10642,25,5815,0.161706655,0.677548413,0.386768863,1.198182878,0.299686909,DB0086310040070_,1.205016987,-0.389274271,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,ranitidine,DB00863
,178405,DB00996,10043414,68,38885,46,22379,0.436175517,0.850773963,0.576475076,1.265637756,0.604751212,DB0099610043414_,0.502938126,-0.161608799,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,178407,DB00126,10043521,38,10133,12,5933,0.076942188,1.85405728,0.94753044,3.900555669,0.173070398,DB0012610043521_,1.754056841,0.617376362,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,178511,DB00126,10068319,83,10088,31,5914,0.032083368,1.569571524,1.026155115,2.457221118,0.089291263,DB0012610068319_,2.415851632,0.450802667,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,178515,DB00338,10070488,36,33638,14,22258,0.111030415,1.701475972,0.895322814,3.416046683,0.227643528,DB0033810070488_,1.479974348,0.531496093,NA,10070488,Upper-airway cough syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,178527,DB00203,10061225,50,13828,23,8915,0.18861969,1.401515345,0.838763252,2.408401478,0.334806666,DB0020310061225_,1.09420203,0.337554041,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,178546,DB00186,10005364,59,16842,31,9977,0.662488011,1.127463947,0.717517342,1.803357422,0.794254303,DB0018610005364_,0.230351588,0.119970815,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,lorazepam,DB00186
,178554,DB00997,10042772,78,5253,19,3495,2.47463158049908e-05,2.731072371,1.63425408,4.785772661,0.000239491,DB0099710042772_,8.336995712,1.004694342,female,10042772,Syncope,10029205,Nervous system disorders,Nerv,doxorubicin,DB00997
,178565,DB01175,10006451,124,10600,22,4870,8.84019392623171e-06,2.589406912,1.633924438,4.287232082,9.75092309488042e-05,DB0117510006451_,9.235563508,0.951428858,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,escitalopram,DB01175
,178568,DB01394,10012174,16,1424,44,1959,0.017184869,0.500351627,0.262431771,0.908745328,0.054851763,DB0139410012174_,2.903120949,-0.692444173,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,colchicine,DB01394
,178572,DB00363,10016256,45,4583,47,6841,0.088618921,1.429094812,0.92646715,2.202143733,0.192954829,DB0036310016256_,1.645299163,0.357041245,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,clozapine,DB00363
,178573,DB00363,10028606,28,4600,125,6763,9.02487364659376e-09,0.329359433,0.210028864,0.500339678,2.04940651231721e-07,DB0036310028606_,15.40054541,-1.110605623,male,10028606,Myocarditis,10007541,Cardiac disorders,Card,clozapine,DB00363
,178593,DB00363,10037660,52,4576,90,6798,0.438382166,0.858369892,0.596723706,1.22363274,0.606790786,DB0036310037660_,0.499571217,-0.152720163,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,clozapine,DB00363
,178626,DB00563,10047216,25,46621,65,15283,3.89645248598806e-21,0.126059855,0.07610903,0.202862413,4.60306757726724e-19,DB0056310047216_,42.22239382,-2.070998448,male,10047216,Venoocclusive liver disease,10019805,Hepatobiliary disorders,Hepat,methotrexate,DB00563
,178658,DB00682,10087283,32,19427,24,16340,0.689754236,1.121436882,0.639850894,1.990560886,0.812888491,DB0068210087283_,0.207161336,0.114610793,NA,10087283,Red blood cell transfusion,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,178667,DB08895,10074903,236,27878,47,6599,0.323505315,1.188579391,0.864901643,1.664183007,0.491942594,DB0889510074903_,0.709393249,0.172758805,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,178668,DB00285,10001949,67,10884,17,3701,0.315737687,1.340115471,0.776752003,2.438053236,0.483352655,DB0028510001949_,0.727008757,0.292755783,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,178670,DB00422,10005750,45,3390,22,2927,0.035484778,1.765933767,1.035675779,3.095997253,0.096454746,DB0042210005750_,2.33868133,0.568679597,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,methylphenidate,DB00422
,178682,DB00051,10054107,65,25666,20,11400,0.159365979,1.443565411,0.862704613,2.517310497,0.296645759,DB0005110054107_,1.215216584,0.367116033,NA,10054107,Nodule,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,178687,DB00678,10029148,46,15553,33,10691,0.908815957,0.958154617,0.599080667,1.547862262,0.95913476,DB0067810029148_,0.041723693,-0.042746118,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,losartan,DB00678
,178688,DB00091,10038435,45,5465,46,2624,0.000428797,0.46974587,0.303549577,0.726509872,0.002715888,DB0009110038435_,5.908636345,-0.755563434,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,cyclosporine,DB00091
,178689,DB01137,10038435,65,7707,78,5515,0.002728536,0.596357118,0.421576219,0.841211213,0.012512139,DB0113710038435_,4.381055976,-0.516915599,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,levofloxacin,DB01137
,178703,DB00316,10017412,156,65318,69,36884,0.095455806,1.276698111,0.955419107,1.72100199,0.203955117,DB0031610017412_,1.589855323,0.244277144,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,acetaminophen,DB00316
,178705,DB00678,10017412,50,15549,17,10707,0.012202708,2.025226919,1.147518157,3.747636882,0.041709004,DB0067810017412_,3.177038245,0.705681753,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,losartan,DB00678
,178711,DB00374,10053482,81,17635,7,5717,9.49406696103328e-05,3.751234555,1.738606744,9.62878549,0.000762339,DB0037410053482_,7.179119707,1.322085001,female,10053482,Infusion site induration,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,178747,DB01137,10015090,49,7723,42,5551,0.455630105,0.838570843,0.543088556,1.299902477,0.623016038,DB0113710015090_,0.473183017,-0.176056214,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,178748,DB05676,10015090,51,47078,20,25309,0.263151047,1.370867044,0.802843499,2.42813257,0.424950867,DB0567610015090_,0.855781724,0.315443419,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,178750,DB01137,10044565,72,7700,48,5545,0.710818595,1.080205787,0.738088892,1.59317742,0.827557708,DB0113710044565_,0.189276437,0.077151567,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,178761,DB00641,10019974,82,14042,38,12437,0.000892565,1.911196532,1.284803107,2.888886598,0.00501841,DB0064110019974_,5.294642213,0.647729503,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,simvastatin,DB00641
,178791,DB00158,10048294,50,16765,38,8066,0.039602143,0.633056104,0.406566199,0.992964203,0.104856445,DB0015810048294_,2.255163057,-0.457196229,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,folic acid,DB00158
,178810,DB00158,10015090,91,16724,45,8059,0.926901169,0.97445259,0.673850002,1.427083564,0.969116835,DB0015810015090_,0.031370102,-0.025879412,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,178825,DB00682,10074300,65,19394,17,16347,3.45668716367309e-06,3.222597854,1.865958611,5.867040493,4.27370753043966e-05,DB0068210074300_,10.06044374,1.170187821,female,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,warfarin,DB00682
,178826,DB00695,10074300,51,27998,20,20508,0.016132995,1.867793636,1.093759813,3.308560512,0.052165797,DB0069510074300_,2.953328237,0.62475786,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,furosemide,DB00695
,178829,DB08932,10074300,177,19266,43,6554,0.051348678,1.400250767,0.997228727,2.004880135,0.127546779,DB0893210074300_,2.05927209,0.33665134,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,178915,DB00982,10037844,44,3320,35,2066,0.295472891,0.782354169,0.488667657,1.260960053,0.461347636,DB0098210037844_,0.77360343,-0.245447739,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,isotretinoin,DB00982
,178917,DB00115,10040829,98,18327,31,10441,0.003269087,1.800970984,1.190780826,2.793522543,0.014508728,DB0011510040829_,4.233004885,0.588325955,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,178925,DB00321,10022000,54,7393,24,2826,0.527267519,0.86010017,0.521513071,1.457794113,0.684879755,DB0032110022000_,0.378511996,-0.150706419,NA,10022000,Influenza,10021881,Infections and infestations,Infec,amitriptyline,DB00321
,178927,DB01076,10022000,250,25497,193,25390,0.008617798,1.28989094,1.063877694,1.565920601,0.031610501,DB0107610022000_,3.454265914,0.254557672,NA,10022000,Influenza,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,178943,DB06186,10047700,76,2133,97,3549,0.094514032,1.30355181,0.94775736,1.787487585,0.202510808,DB0618610047700_,1.596962021,0.265092701,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ipilimumab,DB06186
,178946,DB00874,10021789,45,3290,19,1957,0.242310195,1.408727841,0.804735218,2.558106973,0.400536018,DB0087410021789_,0.914951585,0.342687056,NA,10021789,Infection,10021881,Infections and infestations,Infec,guaifenesin,DB00874
,178954,DB00065,10020144,47,9417,33,4924,0.195918613,0.744756637,0.466464333,1.201563617,0.344198158,DB0006510020144_,1.066537747,-0.294697776,NA,10020144,Histoplasmosis disseminated,10021881,Infections and infestations,Infec,infliximab,DB00065
,178955,DB00065,10038695,39,9425,18,4939,0.780106655,1.135383446,0.633451073,2.110982648,0.880309353,DB0006510038695_,0.127481896,0.126970432,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,infliximab,DB00065
,178974,DB01240,10046306,105,5646,15,1561,0.0135346,1.935147328,1.117362423,3.590994806,0.04530493,DB0124010046306_,3.094339413,0.660183462,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,178976,DB08932,10046306,210,19233,44,6553,0.002864986,1.626050362,1.168688672,2.307759769,0.013026493,DB0893210046306_,4.340770081,0.486153983,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,178977,DB00820,10052251,58,11857,6,5810,2.20628604559914e-05,4.736938891,2.047625668,13.44361273,0.000217159,DB0082010052251_,8.434882172,1.555391124,female,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,178989,DB00437,10061623,57,6864,78,11468,0.284166949,1.220902645,0.850924221,1.742655684,0.44866933,DB0043710061623_,0.80146912,0.199590458,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,179002,DB09053,10048294,19,2266,32,4020,0.884040092,1.053333764,0.562723248,1.920891648,0.951656815,DB0905310048294_,0.049550797,0.051960148,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,ibrutinib,DB09053
,179023,DB00736,10003246,68,10523,24,5529,0.099195169,1.488657032,0.921378508,2.482495023,0.209627353,DB0073610003246_,1.562423835,0.397874393,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,179025,DB06228,10003246,56,15856,28,16048,0.0020775,2.024163021,1.263445668,3.311288664,0.010035302,DB0622810003246_,4.601646234,0.705156292,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,rivaroxaban,DB06228
,179028,DB00736,10003553,89,10502,17,5536,3.25707652187136e-05,2.759573307,1.628362369,4.952147727,0.000305104,DB0073610003553_,8.094856992,1.015076069,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,179048,DB00374,10013946,237,17479,51,5673,0.007019442,1.508189978,1.108610819,2.086626211,0.026850909,DB0037410013946_,3.617455593,0.410910241,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,179065,DB13961,10021143,31,9426,29,6385,0.235836065,0.724125971,0.421714305,1.246663188,0.392972898,DB1396110021143_,0.934014632,-0.322789908,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,179074,DB13961,10038695,47,9410,26,6388,0.473514564,1.227126721,0.743665972,2.06648448,0.639437453,DB1396110038695_,0.447166469,0.204675438,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,179088,DB09140,10043607,46,3695,14,1784,0.164876148,1.586270029,0.854104639,3.133061211,0.303969155,DB0914010043607_,1.190829046,0.461385367,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,oxygen,DB09140
,179138,DB00153,10000060,83,7340,27,3412,0.122026842,1.42895589,0.913834332,2.299952285,0.244334602,DB0015310000060_,1.409216672,0.356944031,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,179139,DB00959,10006784,38,8040,13,4989,0.06183352,1.813756425,0.943999135,3.714423672,0.146832964,DB0095910006784_,1.918459637,0.595400068,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,179159,DB00203,10024774,68,13810,31,8907,0.121668753,1.414746162,0.911520048,2.240838233,0.243791978,DB0020310024774_,1.411439968,0.346950124,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,179167,DB01307,10003239,48,2476,36,2033,0.740362365,1.09478939,0.692887665,1.743516706,0.850840538,DB0130710003239_,0.16153055,0.090562007,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin detemir,DB01307
,179175,DB00258,10013968,36,642,27,716,0.155389581,1.486591402,0.86680612,2.576982794,0.291359645,DB0025810013968_,1.233196883,0.39648585,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium acetate,DB00258
,179222,DB00480,10034018,33,67395,32,67630,0.901975132,1.034854391,0.616712674,1.738469195,0.957184982,DB0048010034018_,0.043758612,0.034260732,NA,10034018,Parosmia,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,179256,DB00480,10013990,76,67352,88,67574,0.390258838,0.866484604,0.628830804,1.191594436,0.560141482,DB0048010013990_,0.579565881,-0.143310938,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,179259,DB00126,10020919,53,10118,23,5922,0.283342837,1.348695801,0.8114624,2.308289763,0.447689177,DB0012610020919_,0.803656088,0.299138052,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,ascorbic acid,DB00126
,179261,DB00480,10020919,45,67383,41,67621,0.667683844,1.101426044,0.70516799,1.724773596,0.798169392,DB0048010020919_,0.225434433,0.096605744,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,179264,DB01592,10020919,41,6235,13,3054,0.192264856,1.544736672,0.809969915,3.14688556,0.339481978,DB0159210020919_,1.080334417,0.434853457,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,iron,DB01592
,179282,DB00874,10047895,66,3269,47,1929,0.327166537,0.828673588,0.558903765,1.237043725,0.495577673,DB0087410047895_,0.702031181,-0.187928944,NA,10047895,Weight decreased,10022891,Investigations,Inv,guaifenesin,DB00874
,179291,DB00203,10047943,38,13840,19,8919,0.416262124,1.288848925,0.72428858,2.368305388,0.585533357,DB0020310047943_,0.535232126,0.253749514,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,sildenafil,DB00203
,179358,DB01222,10069868,71,9203,44,5361,0.771235311,0.93999202,0.635405794,1.404204685,0.874746396,DB0122210069868_,0.133821268,-0.061883893,NA,10069868,Device issue,10077536,Product issues,Prod,budesonide,DB01222
,179362,DB06186,10012671,25,2184,33,3613,0.41554374,1.253193614,0.712400229,2.179186434,0.584748782,DB0618610012671_,0.536572956,0.225695184,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,ipilimumab,DB06186
,179363,DB06186,10046571,33,2176,28,3618,0.01104758,1.959402667,1.14459697,3.375625438,0.038531269,DB0618610046571_,3.256285195,0.672639665,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ipilimumab,DB06186
,179390,DB01156,10003119,34,13588,24,6304,0.120886741,0.657254477,0.378091613,1.159517397,0.242743161,DB0115610003119_,1.415751345,-0.419684004,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,bupropion,DB01156
,179392,DB01234,10044034,159,31466,167,32721,0.955733631,0.990068968,0.791303131,1.238367758,0.993412234,DB0123410044034_,0.006609561,-0.009980673,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,179393,DB00924,10020937,144,10018,35,4216,0.002897599,1.731407848,1.187365603,2.586785881,0.013136147,DB0092410020937_,4.332387506,0.548934862,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,179400,DB00316,10062189,74,65400,14,36939,4.85691821319339e-05,2.985423467,1.67180825,5.725715556,0.000431225,DB0031610062189_,7.748881079,1.093741602,female,10062189,Vitamin D decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,179406,DB00316,10062262,102,65372,43,36910,0.119210821,1.33931512,0.928889578,1.960569106,0.240139206,DB0031610062262_,1.426536498,0.292158379,NA,10062262,Spinal operation,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,179421,DB00126,10038428,42,10129,36,5909,0.099495172,0.680646378,0.42514687,1.094724752,0.210099692,DB0012610038428_,1.560173137,-0.384712376,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,ascorbic acid,DB00126
,179431,DB06643,10018286,79,52342,6,7509,0.141352991,1.888876005,0.829831221,5.303309367,0.271760983,DB0664310018286_,1.302832337,0.635981946,NA,10018286,Gingival pain,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,179434,DB01373,10044016,38,22682,15,7366,0.523739884,0.822690105,0.441808889,1.610943699,0.681847591,DB0137310044016_,0.38294912,-0.195175692,NA,10044016,Tooth abscess,10021881,Infections and infestations,Infec,calcium,DB01373
,179446,DB09020,10021097,51,1903,52,1552,0.270546381,0.79992523,0.529532803,1.207888733,0.433220324,DB0902010021097_,0.83650885,-0.223237018,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,bisacodyl,DB09020
,179464,DB00668,10002424,35,10056,25,4278,0.048833197,0.595608184,0.345973377,1.039533705,0.122805352,DB0066810002424_,2.09715468,-0.518172237,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,epinephrine,DB00668
,179465,DB00465,10046735,43,2061,8,875,0.029652583,2.281443381,1.054616305,5.642110591,0.083939275,DB0046510046735_,2.47766166,0.824808305,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,ketorolac,DB00465
,179467,DB01238,10011224,68,5182,25,3477,0.010310354,1.824934893,1.136059009,3.019185808,0.036462517,DB0123810011224_,3.311470475,0.601544312,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,aripiprazole,DB01238
,179478,DB08896,10046571,36,787,14,1026,7.00061123530684e-05,3.350229779,1.74889622,6.773322184,0.000587051,DB0889610046571_,7.440399238,1.209028934,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,regorafenib,DB08896
,179479,DB00390,10012378,43,4102,27,3274,0.397649447,1.271081983,0.765863566,2.144150145,0.567391757,DB0039010012378_,0.566705284,0.239868493,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,digoxin,DB00390
,179481,DB00641,10029354,63,14061,101,12374,0.000205083,0.548943244,0.393842373,0.760085622,0.001471438,DB0064110029354_,6.521514891,-0.599760224,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,simvastatin,DB00641
,179487,DB00215,10047942,120,10983,52,5224,0.622975245,1.097631502,0.78502425,1.553202014,0.763131973,DB0021510047942_,0.270324297,0.093154678,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,citalopram,DB00215
,179488,DB00390,10047942,31,4114,25,3276,1,0.987418185,0.562965593,1.747944036,1,DB0039010047942_,0,-0.012661636,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,digoxin,DB00390
,179489,DB01136,10047942,140,9744,125,10990,0.063107962,1.263199396,0.983776002,1.623417019,0.149165306,DB0113610047942_,1.90270015,0.233647706,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,carvedilol,DB01136
,179516,DB05259,10022094,83,11187,21,2707,0.804867352,0.956384453,0.58559442,1.628869249,0.894427482,DB0525910022094_,0.11157145,-0.0445953,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,179536,DB00425,10016766,44,12651,22,7462,0.61014668,1.179695331,0.691391408,2.068435822,0.752324346,DB0042510016766_,0.284587736,0.165256211,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,179565,DB00080,10039020,23,617,42,871,0.368786615,0.773182623,0.438997704,1.330984318,0.538426205,DB0008010039020_,0.61910483,-0.257240006,NA,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,daptomycin,DB00080
,179571,DB00331,10072268,53,24893,57,20695,0.18078782,0.773026189,0.521391244,1.144384512,0.324866758,DB0033110072268_,1.124340156,-0.257442351,NA,10072268,Drug-induced liver injury,10019805,Hepatobiliary disorders,Hepat,metformin,DB00331
,179622,DB00820,10052915,84,11831,14,5802,5.07169330196783e-05,2.942294903,1.658113659,5.61606952,0.000447497,DB0082010052915_,7.711839958,1.079189856,female,10052915,Catheter placement,10042613,Surgical and medical procedures,Surg,tadalafil,DB00820
,179631,DB00451,10003598,51,47220,24,15395,0.140716963,0.692812297,0.418523707,1.177341826,0.270841385,DB0045110003598_,1.306221924,-0.366996172,NA,10003598,Atelectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,179679,DB01610,10016256,19,922,35,1183,0.214926065,0.696643611,0.373827266,1.261163376,0.367340634,DB0161010016256_,1.001465704,-0.361481318,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,valganciclovir,DB01610
,179691,DB00295,10020919,44,14619,21,9581,0.254500472,1.373159484,0.798648475,2.432860063,0.415190226,DB0029510020919_,0.879018488,0.317114278,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,morphine,DB00295
,179725,DB00451,10048302,32,47239,22,15397,0.010378922,0.474085851,0.266989448,0.856685767,0.036675402,DB0045110048302_,3.305648997,-0.746366854,NA,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,179727,DB00537,10048302,22,7535,41,4257,4.26548955942419e-06,0.303183186,0.171736048,0.52181191,5.13362605629418e-05,DB0053710048302_,9.877113222,-1.193418083,male,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,ciprofloxacin,DB00537
,179728,DB00736,10048302,46,10545,32,5521,0.23255542,0.752664955,0.468454076,1.222744646,0.389010673,DB0073610048302_,0.944148499,-0.284135097,NA,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,esomeprazole,DB00736
,179730,DB00864,10048302,17,6852,54,8338,0.00028916,0.383121708,0.208001875,0.671847683,0.001957646,DB0086410048302_,6.236012441,-0.959402565,NA,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,tacrolimus,DB00864
,179744,DB00635,10055181,50,33003,76,23718,3.92803891812754e-05,0.472804732,0.323970762,0.684781002,0.000359188,DB0063510055181_,7.931665478,-0.749072806,NA,10055181,BK virus infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,179755,DB00635,10065381,33,33020,61,23733,8.0880590605296e-06,0.388834818,0.246475882,0.603605948,9.03696630843871e-05,DB0063510065381_,9.311601932,-0.944600659,NA,10065381,Polyomavirus-associated nephropathy,10021881,Infections and infestations,Infec,prednisone,DB00635
,179802,DB00005,10061852,65,128017,25,42394,0.542090707,0.86103763,0.535213178,1.425866923,0.697379319,DB0000510061852_,0.3604258,-0.14961707,NA,10061852,Eye operation,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,179805,DB00331,10048294,107,24839,135,20617,0.001464447,0.657885832,0.505275979,0.854805696,0.007540991,DB0033110048294_,4.887401647,-0.41872387,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,metformin,DB00331
,179808,DB00758,10006784,40,8260,36,10038,0.20479434,1.350249492,0.838161676,2.182256207,0.354816453,DB0075810006784_,1.036154658,0.300289385,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,179849,DB00421,10014387,42,8861,12,5240,0.023725743,2.069646182,1.068510376,4.322610664,0.070598421,DB0042110014387_,2.650747505,0.727377666,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,spironolactone,DB00421
,179871,DB00864,10013573,87,6782,73,8319,0.020257485,1.46181962,1.05678948,2.027039593,0.062425213,DB0086410013573_,2.77378603,0.379681975,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,tacrolimus,DB00864
,179872,DB01024,10013573,34,2177,19,2101,0.071368727,1.726780916,0.953912205,3.215547717,0.163647859,DB0102410013573_,1.81003836,0.546258933,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,mycophenolic acid,DB01024
,179873,DB01109,10013573,104,4308,61,4209,0.001610758,1.665632484,1.199077221,2.330757649,0.008142854,DB0110910013573_,4.810614588,0.510204921,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,heparin,DB01109
,179874,DB01233,10013573,111,3310,38,1688,0.034765845,1.489540844,1.016786308,2.224396768,0.094971964,DB0123310013573_,2.35417355,0.398467914,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,metoclopramide,DB01233
,179881,DB00281,10018884,78,11380,39,5632,1,0.989803875,0.664678007,1.495535437,1,DB0028110018884_,0,-0.010248461,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,lidocaine,DB00281
,179900,DB00864,10029155,60,6809,69,8323,0.789903266,1.06288557,0.738109065,1.526912198,0.886130966,DB0086410029155_,0.120890522,0.060987446,NA,10029155,Nephropathy toxic,10038359,Renal and urinary disorders,Renal,tacrolimus,DB00864
,179911,DB00012,10029354,40,1606,27,1286,0.535598047,1.186223829,0.705833492,2.021823474,0.692151661,DB0001210029354_,0.367950184,0.170775009,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,darbepoetin alfa,DB00012
,179916,DB00959,10029354,62,8016,59,4943,0.018700298,0.648041936,0.445483966,0.943514845,0.05860705,DB0095910029354_,2.83690029,-0.433799869,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,methylprednisolone,DB00959
,179917,DB01109,10029354,39,4373,38,4232,1,0.99322436,0.617513396,1.59877769,1,DB0110910029354_,0,-0.006798699,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,heparin,DB01109
,179934,DB00012,10037660,57,1589,33,1280,0.161044291,1.391229877,0.884556814,2.220032932,0.29888083,DB0001210037660_,1.207710348,0.330188159,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,darbepoetin alfa,DB00012
,180012,DB00563,10050551,52,46594,7,15341,0.022538818,2.445939796,1.106343244,6.383997778,0.067815112,DB0056310050551_,2.690970212,0.894429424,NA,10050551,Lupus-like syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,180020,DB00193,10022093,96,19224,12,8690,1.750172905871e-06,3.6158335,1.976249761,7.246196045,2.35431396268266e-05,DB0019310022093_,10.65667609,1.285322396,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,180108,DB00213,10040943,43,18852,20,13401,0.125459791,1.528312676,0.879336864,2.74371757,0.2493145,DB0021310040943_,1.389040125,0.424164301,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,180111,DB00761,10040943,36,15271,29,8596,0.15600652,0.698806893,0.416251254,1.182397924,0.292172178,DB0076110040943_,1.230412,-0.358380837,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,potassium chloride,DB00761
,180132,DB08932,10020937,174,19269,53,6544,0.539901499,1.114949574,0.814334606,1.548552179,0.695552748,DB0893210020937_,0.363048429,0.108809179,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,180155,DB08932,10048634,131,19312,20,6577,0.00033663,2.230769868,1.385667973,3.774802238,0.002220406,DB0893210048634_,6.110065322,0.802346758,NA,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,180165,DB00787,10013952,71,16929,53,17195,0.104993213,1.3606541,0.93931511,1.981624105,0.218507252,DB0078710013952_,1.520936075,0.30796554,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,180167,DB06228,10013952,34,15878,20,16056,0.056751161,1.719018096,0.961070347,3.15325392,0.137346455,DB0622810013952_,1.985248679,0.541753254,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,180168,DB00480,10016322,651,66777,516,67146,5.56721688083021e-05,1.268594085,1.127874161,1.427393166,0.00048383,DB0048010016322_,7.633777553,0.237909268,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,180170,DB06228,10016322,169,15743,82,15994,1.83301385610625e-08,2.093776281,1.597456878,2.762874713,3.87149611954622e-07,DB0622810016322_,14.76445462,0.738969269,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,180171,DB00482,10037377,38,8221,26,3045,0.022933346,0.541399659,0.319637848,0.930319029,0.068746423,DB0048210037377_,2.677330576,-0.613597531,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,celecoxib,DB00482
,180176,DB00584,10025482,59,2022,30,1844,0.009749212,1.793274598,1.131121699,2.896967688,0.034879274,DB0058410025482_,3.355862482,0.584043333,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,enalapril,DB00584
,180177,DB00196,10037153,50,5033,14,3271,0.004354176,2.320893627,1.260697741,4.553626154,0.018295693,DB0019610037153_,4.00108961,0.841952296,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,fluconazole,DB00196
,180178,DB00571,10037153,65,5058,18,2591,0.019382242,1.849688365,1.081171979,3.320824293,0.06030923,DB0057110037153_,2.808270117,0.615017174,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,propranolol,DB00571
,180179,DB00927,10037153,50,7447,16,5000,0.008013292,2.098038833,1.173465892,3.951747192,0.029817295,DB0092710037153_,3.512666697,0.741003019,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,famotidine,DB00927
,180203,DB00338,10017918,85,33589,35,22237,0.019253686,1.607777646,1.072291273,2.457436778,0.06001223,DB0033810017918_,2.813206906,0.474852881,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,omeprazole,DB00338
,180206,DB01162,10028813,15,258,54,1648,0.07282488,1.773710418,0.915481222,3.247105156,0.166235516,DB0116210028813_,1.794349727,0.573073634,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,terazosin,DB01162
,180226,DB00515,10019211,41,1829,23,2128,0.005202048,2.073671062,1.210188751,3.635077558,0.021120766,DB0051510019211_,3.857498542,0.729320496,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cisplatin,DB00515
,180230,DB06723,10053762,36,994,18,592,0.667857163,1.190981976,0.652008553,2.24932523,0.798245937,DB0672310053762_,0.225338537,0.174778157,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,aluminum hydroxide,DB06723
,180232,DB06605,10047513,65,14008,55,12978,0.647847226,1.094889021,0.752148286,1.598921966,0.782917966,DB0660510047513_,0.244727358,0.090653007,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,apixaban,DB06605
,180238,DB06605,10042772,144,13929,132,12901,0.95176939,1.010397188,0.79124597,1.291073853,0.989861255,DB0660510042772_,0.010190492,0.010343509,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,180262,DB00758,10019196,42,8258,36,10038,0.1383204,1.418098675,0.885967942,2.280441843,0.26742317,DB0075810019196_,1.31892297,0.349317013,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,180275,DB00177,10050584,43,4757,12,2838,0.01716057,2.137605947,1.105054778,4.460771028,0.054787512,DB0017710050584_,2.904292987,0.759686486,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,valsartan,DB00177
,180276,DB00555,10050584,48,6999,17,3469,0.289938917,1.399423989,0.789006888,2.599743651,0.455164358,DB0055510050584_,0.787096699,0.336060716,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,lamotrigine,DB00555
,180277,DB01202,10050584,49,6665,16,5702,0.000430587,2.619727118,1.462603034,4.940814672,0.002725583,DB0120210050584_,5.905072865,0.963070159,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,levetiracetam,DB01202
,180288,DB00758,10060933,35,8265,28,10046,0.100742973,1.519305366,0.897126326,2.595108407,0.212011749,DB0075810060933_,1.551113588,0.418253234,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,180308,DB00009,10006093,23,1328,53,1498,0.004850715,0.489630237,0.284753335,0.818022879,0.019978227,DB0000910006093_,3.913112232,-0.714104792,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,alteplase,DB00009
,180317,DB00186,10021113,64,16837,6,10002,7.19397810374391e-08,6.33709097,2.755369511,17.91105665,1.342995131086e-06,DB0018610021113_,13.52060827,1.846419826,female,10021113,Hypothermia,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,180330,DB00582,10029354,23,1107,37,1537,0.599976214,0.863147211,0.486655464,1.501155348,0.744506371,DB0058210029354_,0.29503387,-0.147170022,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,voriconazole,DB00582
,180340,DB01234,10024670,33,31592,34,32854,1,1.009360743,0.605779799,1.680101764,1,DB0123410024670_,0,0.009317203,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,dexamethasone,DB01234
,180353,DB00480,10019194,51,67377,21,67641,0.000362089,2.438204965,1.440480983,4.267382669,0.002359617,DB0048010019194_,6.049255798,0.891262099,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,180356,DB01234,10019194,47,31578,12,32876,1.53613875974869e-06,4.07722997,2.129387565,8.445731523,2.10402307016313e-05,DB0123410019194_,10.76907421,1.405417829,female,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,180358,DB01029,10033425,35,1305,15,886,0.146957001,1.583853711,0.836953273,3.141141262,0.279738189,DB0102910033425_,1.273901154,0.459860935,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,irbesartan,DB01029
,180362,DB00480,10035532,23,67405,31,67631,0.340833353,0.744427251,0.414461816,1.318939243,0.510080831,DB0048010035532_,0.673186073,-0.295140147,NA,10035532,Platelet disorder,10005329,Blood and lymphatic system disorders,Blood,lenalidomide,DB00480
,180422,DB00343,10020751,76,8660,29,5066,0.053499821,1.533028255,0.985908823,2.443221228,0.131565962,DB0034310020751_,2.02824694,0.427245031,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,diltiazem,DB00343
,180423,DB00264,10043882,62,29545,30,24862,0.011878617,1.739069991,1.107036374,2.787133071,0.040839953,DB0026410043882_,3.198094441,0.553350482,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,metoprolol,DB00264
,180443,DB00683,10012218,48,1536,72,1566,0.050276195,0.679771559,0.45841757,1.00038515,0.125507431,DB0068310012218_,2.07539031,-0.38599848,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,midazolam,DB00683
,180444,DB00818,10012218,25,1395,32,1645,0.789932575,0.921256798,0.52070328,1.613133431,0.886130966,DB0081810012218_,0.120890522,-0.082016457,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,propofol,DB00818
,180452,DB00813,10027646,16,10556,79,10089,6.5150148695197e-12,0.193594075,0.105469198,0.334476834,2.57902358200791e-10,DB0081310027646_,22.07844006,-1.641991708,male,10027646,Miosis,10015919,Eye disorders,Eye,fentanyl,DB00813
,180516,DB00683,10045555,21,1563,30,1608,0.262091241,0.720228903,0.390105126,1.306917569,0.423799223,DB0068310045555_,0.858495466,-0.328186196,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,midazolam,DB00683
,180524,DB01006,10000081,88,5859,6,171,0.053951536,0.428149064,0.1853612,1.215009891,0.132410468,DB0100610000081_,2.021848574,-0.848283864,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,letrozole,DB01006
,180534,DB00804,10019211,193,2807,31,868,0.000561288,1.92497488,1.301066114,2.933701289,0.003395502,DB0080410019211_,5.685303629,0.654912918,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,dicyclomine,DB00804
,180539,DB00736,10006002,57,10534,17,5536,0.037514761,1.762036116,1.00928404,3.23452037,0.10060882,DB0073610006002_,2.296515349,0.566470024,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,180542,DB06643,10018292,48,52373,6,7509,1,1.147035136,0.489913508,3.281121051,1,DB0664310018292_,0,0.137180471,NA,10018292,Gingivitis,10021881,Infections and infestations,Infec,denosumab,DB06643
,180568,DB08931,10005737,65,6512,14,2432,0.074039499,1.733901552,0.960816792,3.351841444,0.168270133,DB0893110005737_,1.782184654,0.550374102,NA,10005737,Blood pressure diastolic decreased,10022891,Investigations,Inv,riociguat,DB08931
,180574,DB00390,10020646,25,4120,36,3265,0.027018408,0.550383699,0.315967194,0.944691245,0.078058788,DB0039010020646_,2.550293038,-0.59713961,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,digoxin,DB00390
,180591,DB01306,10016173,104,4104,102,3764,0.671810195,0.935170668,0.70208698,1.245832164,0.800827851,DB0130610016173_,0.222109273,-0.067026234,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin aspart,DB01306
,180592,DB09020,10016173,101,1853,86,1518,0.821024999,0.96209118,0.708475126,1.308899159,0.904700649,DB0902010016173_,0.100151165,-0.038646051,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,bisacodyl,DB09020
,180605,DB01306,10024855,29,4179,30,3836,0.695665586,0.887339322,0.512829705,1.5331315,0.816830399,DB0130610024855_,0.202323795,-0.11952782,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,insulin aspart,DB01306
,180606,DB06724,10024855,55,7874,22,3897,0.466332783,1.237245696,0.740961124,2.133962915,0.633093464,DB0672410024855_,0.457137215,0.212887696,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,180608,DB00287,10028813,41,1360,11,806,0.019287797,2.208261845,1.106925978,4.792187826,0.060093609,DB0028710028813_,2.811851778,0.792205711,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,travoprost,DB00287
,180610,DB01306,10030124,48,4160,39,3827,0.590948611,1.132230705,0.724776034,1.778538444,0.737440797,DB0130610030124_,0.304569469,0.124189762,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,insulin aspart,DB01306
,180623,DB00421,10019974,38,8865,15,5237,0.202013326,1.496526448,0.803300242,2.931520835,0.351401552,DB0042110019974_,1.045825686,0.403146721,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,spironolactone,DB00421
,180663,DB01413,10043554,41,1179,39,1620,0.109044186,1.444296693,0.902425557,2.314941918,0.224616879,DB0141310043554_,1.493359088,0.367622485,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,cefepime,DB01413
,180690,DB00213,10043521,42,18853,18,13403,0.087448011,1.658787919,0.933901085,3.062971395,0.190866553,DB0021310043521_,1.656180768,0.506087166,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,180691,DB00316,10043521,220,65254,63,36890,6.0193419640696e-07,1.97415192,1.485233373,2.656440371,9.13501175089892e-06,DB0031610043521_,11.60339608,0.680138898,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,180696,DB01104,10043521,46,15417,13,7273,0.123517724,1.669242113,0.886058598,3.37004303,0.246435048,DB0110410043521_,1.400656817,0.512369699,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,180700,DB00104,10069218,61,1420,40,1037,0.681055886,1.113669551,0.728930053,1.717645735,0.807122451,DB0010410069218_,0.214279887,0.107660465,NA,10069218,Syringe issue,10077536,Product issues,Prod,octreotide,DB00104
,180711,DB11093,10025482,59,1598,15,645,0.117848131,1.587328534,0.881236223,3.035665633,0.237968666,DB1109310025482_,1.435616268,0.462052436,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,calcium citrate,DB11093
,180744,DB00321,10019063,49,7398,23,2827,0.42842746,0.814092779,0.485583311,1.402910733,0.596968606,DB0032110019063_,0.515890753,-0.20568094,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,amitriptyline,DB00321
,180745,DB00321,10047513,62,7385,15,2835,0.124606643,1.586723001,0.890219499,3.008437485,0.247977409,DB0032110047513_,1.394417628,0.461670884,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,amitriptyline,DB00321
,180748,DB09038,10047700,87,2161,75,2466,0.092344216,1.323634818,0.955237419,1.837695261,0.19897957,DB0903810047700_,1.614553123,0.280381603,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,empagliflozin,DB09038
,180786,DB04868,10012735,53,1588,51,1465,0.842469607,0.95871983,0.635797281,1.446881898,0.919801687,DB0486810012735_,0.08359719,-0.042156395,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,nilotinib,DB04868
,180787,DB00213,10018627,33,18862,37,13384,0.06781721,0.632887664,0.383332658,1.040782238,0.157408289,DB0021310018627_,1.848912284,-0.457462338,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,180791,DB00321,10029331,69,7378,54,2796,0.000103095,0.484256153,0.333297853,0.706743709,0.000818936,DB0032110029331_,7.107504202,-0.72514127,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,180795,DB00476,10050296,45,17212,9,6168,0.122128743,1.791813498,0.864257118,4.17134763,0.244490023,DB0047610050296_,1.408580777,0.583228234,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,180805,DB00331,10001480,44,24902,42,20710,0.588095873,0.871266918,0.5574881,1.363351321,0.735071119,DB0033110001480_,0.307788023,-0.137806899,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,metformin,DB00331
,180816,DB00046,10061428,66,5393,65,4627,0.480613559,0.871176546,0.607593178,1.249452289,0.645393246,DB0004610061428_,0.437895464,-0.137910629,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,insulin lispro,DB00046
,180848,DB00333,10044066,48,3023,40,3112,0.335895267,1.235284543,0.792437171,1.934828936,0.505016746,DB0033310044066_,0.68316369,0.211301343,NA,10044066,Torsade de pointes,10007541,Cardiac disorders,Card,methadone,DB00333
,180849,DB01118,10044066,36,3027,43,4666,0.297610067,1.290463245,0.803202197,2.062598771,0.463511324,DB0111810044066_,0.768924464,0.255001259,NA,10044066,Torsade de pointes,10007541,Cardiac disorders,Card,amiodarone,DB01118
,180851,DB01118,10047290,24,3039,41,4668,0.704571923,0.89913415,0.51851397,1.527357185,0.822904333,DB0111810047290_,0.194915327,-0.106323034,NA,10047290,Ventricular fibrillation,10007541,Cardiac disorders,Card,amiodarone,DB01118
,180855,DB01234,10061368,27,31598,43,32845,0.093642475,0.652694299,0.387719139,1.080902991,0.201168114,DB0123410061368_,1.603614332,-0.426646407,NA,10061368,Spinal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,180864,DB00987,10007515,28,2076,56,2872,0.119259866,0.691764393,0.421528504,1.111989443,0.240210389,DB0098710007515_,1.42624012,-0.368509854,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,cytarabine,DB00987
,180901,DB00722,10020583,31,25372,23,26009,0.276383036,1.381650413,0.779699912,2.482023231,0.439829436,DB0072210020583_,0.821368274,0.323278736,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,180962,DB00737,10013700,78,2723,15,917,0.051581582,1.751007868,0.993154607,3.293951302,0.128004331,DB0073710013700_,2.05569118,0.560191547,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,meclizine,DB00737
,180984,DB14500,10007882,63,7746,33,4040,1,0.99570433,0.642262643,1.569456017,1,DB1450010007882_,0,-0.004304923,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,potassium,DB14500
,181025,DB00863,10058080,35,10638,19,5821,1,1.007979932,0.560453391,1.867118118,1,DB0086310058080_,0,0.00794826,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,ranitidine,DB00863
,181028,DB14500,10058080,31,7778,23,4050,0.198711339,0.701807326,0.395559788,1.262257915,0.347490356,DB1450010058080_,1.057018368,-0.354096377,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,potassium,DB14500
,181041,DB00169,10074170,60,38631,28,18147,1,1.006613318,0.632459489,1.638229643,1,DB0016910074170_,0,0.006591546,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,181068,DB06282,10033371,81,1459,18,515,0.098143519,1.588144841,0.933304541,2.841569361,0.208050763,DB0628210033371_,1.569973176,0.462566569,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,levocetirizine,DB06282
,181073,DB00112,10001551,30,5903,27,4064,0.344852354,0.764989944,0.438818219,1.33960663,0.514309293,DB0011210001551_,0.664930458,-0.267892591,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,bevacizumab,DB00112
,181090,DB00112,10046571,92,5841,23,4068,2.2247224845814e-06,2.785533798,1.744992607,4.618865057,2.91219275434373e-05,DB0011210046571_,10.44401914,1.024439524,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,bevacizumab,DB00112
,181094,DB00338,10005746,39,33635,23,22249,0.698912842,1.121670485,0.653243798,1.96776358,0.818987281,DB0033810005746_,0.199686725,0.114819078,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,omeprazole,DB00338
,181103,DB01281,10010264,124,8808,29,1769,0.446223065,0.858803112,0.56732488,1.339436247,0.61405022,DB0128110010264_,0.487678562,-0.152215589,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,181104,DB01281,10012378,74,8858,9,1789,0.183171107,1.66052108,0.827007895,3.780616724,0.327873101,DB0128110012378_,1.115128632,0.507131457,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,abatacept,DB01281
,181105,DB09153,10012378,67,7732,26,5673,0.005874851,1.890604719,1.184068628,3.102923069,0.023282392,DB0915310012378_,3.760057892,0.636896735,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,sodium chloride,DB09153
,181110,DB01234,10019304,44,31581,32,32856,0.135743676,1.430496366,0.886580181,2.331267987,0.263721684,DB0123410019304_,1.33286096,0.358021493,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,dexamethasone,DB01234
,181122,DB00959,10023232,83,7995,36,4966,0.072519252,1.43203077,0.955784276,2.184188694,0.165695902,DB0095910023232_,1.797601087,0.359093556,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,methylprednisolone,DB00959
,181130,DB01234,10026865,32,31593,23,32865,0.180041638,1.447304767,0.820660917,2.590722029,0.32389418,DB0123410026865_,1.127338421,0.369703046,NA,10026865,Mass,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,181143,DB01234,10029216,135,31490,53,32835,2.70346705284381e-10,2.655977455,1.918807331,3.723156116,8.25806292667049e-09,DB0123410029216_,18.61207579,0.976812743,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,181148,DB00390,10042674,54,4091,16,3285,0.000238982,2.7096705,1.524402426,5.081591243,0.001671764,DB0039010042674_,6.393875877,0.996827041,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,181149,DB09153,10042674,46,7753,21,5678,0.082209446,1.604163599,0.936916906,2.833343536,0.182014427,DB0915310042674_,1.703669324,0.472602498,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,181152,DB00715,10048959,74,4769,24,2263,0.126577818,1.463039875,0.909533603,2.431806678,0.250912364,DB0071510048959_,1.382651548,0.380516378,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,181153,DB00993,10048959,60,3189,26,1593,0.64430188,1.152716215,0.713138797,1.911033486,0.780474911,DB0099310048959_,0.247852684,0.142121084,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,azathioprine,DB00993
,181155,DB00338,10062519,61,33613,29,22243,0.161224905,1.391923313,0.880455123,2.247506328,0.299120991,DB0033810062519_,1.206907135,0.330686469,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,181161,DB01234,10062519,36,31589,31,32857,0.464995999,1.207899517,0.726197723,2.019859828,0.631861858,DB0123410062519_,0.459084488,0.188882915,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,181173,DB00158,10035528,135,16680,121,7983,8.38408692538107e-07,0.533962685,0.414051313,0.689259888,1.22635350491731e-05,DB0015810035528_,11.30888033,-0.62742932,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,folic acid,DB00158
,181188,DB01068,10046306,75,13688,25,6815,0.088566089,1.493616954,0.937740446,2.45435999,0.192871554,DB0106810046306_,1.645730834,0.401200664,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,clonazepam,DB01068
,181194,DB00959,10003246,46,8032,7,4995,9.2045676210259e-05,4.086344147,1.83062909,10.73279253,0.000743408,DB0095910003246_,7.204265843,1.407650719,female,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,methylprednisolone,DB00959
,181196,DB00563,10017076,129,46517,21,15327,0.001673372,2.023885544,1.269358857,3.382162738,0.008403625,DB0056310017076_,4.779092157,0.7050192,NA,10017076,Fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,181246,DB00804,10013968,147,2853,37,862,0.370158295,1.200327271,0.824628547,1.785861058,0.539784233,DB0080410013968_,0.616585788,0.182594246,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dicyclomine,DB00804
,181285,DB01076,10037437,37,25710,28,25555,0.320937891,1.313451136,0.782052697,2.228895177,0.489205084,DB0107610037437_,0.714973482,0.272658128,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,181301,DB00381,10002383,39,29321,41,22846,0.214565118,0.741171802,0.465455594,1.178433401,0.366974274,DB0038110002383_,1.002463531,-0.299522828,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,amlodipine,DB00381
,181321,DB01076,10013916,51,25696,29,25554,0.018273227,1.748873072,1.087325011,2.862596705,0.057529259,DB0107610013916_,2.85546161,0.558971621,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,181336,DB00736,10013952,64,10527,17,5536,0.009803391,1.979730651,1.14417265,3.609622411,0.035018298,DB0073610013952_,3.351884562,0.682960801,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,esomeprazole,DB00736
,181338,DB00422,10013968,74,3361,54,2895,0.371805014,1.180338433,0.816825873,1.715068607,0.541479613,DB0042210013968_,0.613449862,0.165801205,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylphenidate,DB00422
,181349,DB00736,10017412,34,10557,18,5535,1,0.990335984,0.543257563,1.864414665,1,DB0073610017412_,0,-0.009711015,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,esomeprazole,DB00736
,181358,DB00736,10023547,32,10559,25,5528,0.16163954,0.670117786,0.384354173,1.180800275,0.299608717,DB0073610023547_,1.205277932,-0.400301782,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,esomeprazole,DB00736
,181363,DB00476,10036790,49,17208,11,6166,0.186932899,1.596060108,0.818158861,3.406292683,0.332647164,DB0047610036790_,1.100672919,0.46753816,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,181366,DB01050,10036790,48,18060,28,9343,0.628804147,0.886861814,0.544850915,1.469053201,0.767981646,DB0105010036790_,0.263989444,-0.1200661,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,181367,DB00422,10037844,67,3368,38,2911,0.038599307,1.523814622,1.005209767,2.339971237,0.10282615,DB0042210037844_,2.274715579,0.421216811,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,methylphenidate,DB00422
,181437,DB00836,10001760,69,5466,15,4060,2.08755089173493e-06,3.416340212,1.93147122,6.440356705,2.75458208781388e-05,DB0083610001760_,10.49965973,1.228569865,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,loperamide,DB00836
,181440,DB00836,10006451,73,5462,29,4046,0.004571775,1.864533092,1.194824049,2.980167951,0.019008085,DB0083610006451_,3.96289086,0.623010669,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,loperamide,DB00836
,181456,DB01137,10016807,37,7735,28,5565,0.899872284,0.95073966,0.565499367,1.614901223,0.956571579,DB0113710016807_,0.044399659,-0.050515008,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,levofloxacin,DB01137
,181471,DB01296,10019211,63,1386,25,958,0.020038415,1.741440239,1.071008808,2.911122285,0.061856692,DB0129610019211_,2.782934989,0.554712494,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,glucosamine,DB01296
,181473,DB01137,10020642,38,7734,22,5571,0.434805521,1.244178681,0.716427136,2.211255102,0.603277113,DB0113710020642_,0.50537863,0.218475618,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,levofloxacin,DB01137
,181480,DB01137,10028372,91,7681,61,5532,0.680318946,1.074434062,0.766836568,1.514381752,0.806611945,DB0113710028372_,0.214912588,0.071794069,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,181482,DB00836,10028810,92,5443,40,4035,0.004467007,1.704937618,1.161295637,2.543051888,0.018665494,DB0083610028810_,3.98107869,0.533528523,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,loperamide,DB00836
,181483,DB01137,10028810,86,7686,41,5552,0.02993156,1.515131156,1.031098211,2.258795187,0.084565062,DB0113710028810_,2.47023408,0.415502007,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,levofloxacin,DB01137
,181485,DB00126,10029331,140,10031,91,5854,0.450064375,0.897840614,0.683220359,1.184669079,0.617735416,DB0012610029331_,0.481695042,-0.107762716,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,181498,DB01296,10037844,48,1401,25,958,0.332716287,1.312747234,0.787307154,2.238093612,0.501689284,DB0129610037844_,0.689774306,0.272122067,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,glucosamine,DB01296
,181510,DB01296,10047700,33,1416,20,963,0.777674368,1.122118875,0.620832188,2.076732837,0.878774377,DB0129610047700_,0.129227096,0.115218751,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,glucosamine,DB01296
,181525,DB01261,10000059,35,3746,28,3275,0.80013659,1.092784133,0.64433656,1.869311784,0.891935108,DB0126110000059_,0.114361898,0.08872869,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,sitagliptin,DB01261
,181576,DB00863,10017955,62,10611,62,5778,0.000898064,0.544529472,0.376122034,0.788415221,0.005042855,DB0086310017955_,5.289782811,-0.607833211,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,181578,DB00404,10021015,69,19823,22,9840,0.074373316,1.55684771,0.950826343,2.644494151,0.168809861,DB0040410021015_,1.778982278,0.442663078,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,alprazolam,DB00404
,181581,DB00863,10038435,124,10549,94,5746,0.018449253,0.718577991,0.544083357,0.951622972,0.057960343,DB0086310038435_,2.847996238,-0.330481032,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,ranitidine,DB00863
,181588,DB01175,10047571,57,10667,23,4869,0.717150746,1.131199364,0.685039628,1.926246464,0.832794671,DB0117510047571_,0.182968161,0.123278454,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,escitalopram,DB01175
,181589,DB06637,10047571,53,6109,15,2004,0.674124067,1.159053971,0.641950083,2.219068654,0.802343323,DB0663710047571_,0.22021868,0.14760413,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,dalfampridine,DB06637
,181602,DB00571,10008479,42,5081,23,2586,0.792869966,0.929406184,0.544903177,1.622786643,0.88774012,DB0057110008479_,0.119076237,-0.073209409,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,181603,DB00571,10011224,57,5066,31,2578,0.82071043,0.935696778,0.592307478,1.503477794,0.904519726,DB0057110011224_,0.100351166,-0.06646381,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,propranolol,DB00571
,181604,DB00571,10012378,96,5027,50,2559,0.929629317,0.977365603,0.684927547,1.409575044,0.971029456,DB0057110012378_,0.029398475,-0.022894488,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,propranolol,DB00571
,181612,DB00571,10047899,60,5063,24,2585,0.35413651,1.276422849,0.780904761,2.148386824,0.524008003,DB0057110047899_,0.646248322,0.244061516,NA,10047899,Weight increased,10022891,Investigations,Inv,propranolol,DB00571
,181613,DB00737,10047899,46,2755,9,923,0.158701672,1.71206107,0.823920227,3.994108827,0.295765275,DB0073710047899_,1.218189128,0.537697949,NA,10047899,Weight increased,10022891,Investigations,Inv,meclizine,DB00737
,181638,DB00423,10011906,68,2399,47,993,0.009273944,0.598961779,0.403735358,0.895005341,0.03351421,DB0042310011906_,3.395785739,-0.51255749,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,methocarbamol,DB00423
,181715,DB01068,10029354,29,13734,35,6805,0.000454055,0.410561591,0.241852382,0.692065897,0.002850112,DB0106810029354_,5.860397057,-0.890229323,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,clonazepam,DB01068
,181788,DB00218,10022116,39,1403,23,927,0.695681755,1.120339398,0.647793711,1.978726197,0.816830399,DB0021810022116_,0.202323795,0.113631674,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,moxifloxacin,DB00218
,181792,DB01060,10027175,70,8517,30,5051,0.146663178,1.383749879,0.88882037,2.202221104,0.279269896,DB0106010027175_,1.275576597,0.324797118,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,amoxicillin,DB01060
,181793,DB01060,10038695,40,8547,44,5037,0.004536703,0.535763353,0.339753223,0.842700756,0.018893644,DB0106010038695_,3.968929722,-0.62406272,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amoxicillin,DB01060
,181811,DB00193,10049438,52,19268,23,8679,1,1.018386294,0.611862525,1.744687706,1,DB0019310049438_,0,0.01821931,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,181814,DB00476,10049438,37,17220,14,6163,0.87384037,0.945870971,0.499021979,1.895417906,0.945166209,DB0047610049438_,0.056394484,-0.055649114,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,181827,DB00973,10043607,30,3821,24,2997,1,0.980434802,0.552849613,1.756345887,1,DB0097310043607_,0,-0.019759131,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,ezetimibe,DB00973
,181844,DB00381,10042458,54,29306,42,22845,1,1.002256951,0.657029995,1.538167538,1,DB0038110042458_,0,0.002254407,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,181846,DB00814,10042458,61,8226,32,3383,0.3023115,0.78395281,0.502054311,1.245393274,0.46868134,DB0081410042458_,0.757832187,-0.243406452,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,meloxicam,DB00814
,181866,DB00497,10013946,85,19182,51,16324,0.057510855,1.418326899,0.99009419,2.049785073,0.138761964,DB0049710013946_,1.974995307,0.349477937,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,181867,DB00813,10013946,39,10533,18,10150,0.011060375,2.087802497,1.165373611,3.880478661,0.038567519,DB0081310013946_,3.25534483,0.736112076,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,181872,DB00451,10058920,102,47169,19,15400,0.025848901,1.752625736,1.066533062,3.03127221,0.07535452,DB0045110058920_,2.58555137,0.561115084,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,181873,DB00497,10058920,33,19234,25,16350,0.694328976,1.122051093,0.646945735,1.969081368,0.815971973,DB0049710058920_,0.203375271,0.115158344,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,181881,DB00472,10022061,61,10698,10,4302,0.005416107,2.452820942,1.245717373,5.375352852,0.021799357,DB0047210022061_,3.825874808,0.897238767,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,181883,DB00472,10022095,76,10683,15,4297,0.010052403,2.037873325,1.159650817,3.822903278,0.03571606,DB0047210022095_,3.332154827,0.711906776,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,181934,DB09270,10025482,116,2998,48,2320,0.000219428,1.8699167,1.318561773,2.687447868,0.001557567,DB0927010025482_,6.46463028,0.625893885,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,181935,DB13867,10025482,155,4395,57,2497,0.005632332,1.54486829,1.128495052,2.140192495,0.022513054,DB1386710025482_,3.793659963,0.434938658,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,181937,DB13867,10033425,120,4430,38,2516,0.001393456,1.793377518,1.231296316,2.664823115,0.007231359,DB1386710033425_,4.929328333,0.584100724,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone,DB13867
,181942,DB00381,10061016,26,29334,32,22855,0.086109754,0.633058957,0.36223857,1.096738749,0.188529831,DB0038110061016_,1.668499033,-0.457191723,NA,10061016,Blood test abnormal,10022891,Investigations,Inv,amlodipine,DB00381
,181945,DB00563,10061016,38,46608,14,15334,0.747902489,0.892986304,0.472810946,1.784782604,0.856771275,DB0056310061016_,0.154584286,-0.113184036,NA,10061016,Blood test abnormal,10022891,Investigations,Inv,methotrexate,DB00563
,181953,DB00563,10048762,67,46579,13,15335,0.091171228,1.696699601,0.927824584,3.35167514,0.197115833,DB0056310048762_,1.623963739,0.528684953,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,181957,DB00115,10017626,40,18385,16,10456,0.266780356,1.421794654,0.778191253,2.720995793,0.428993128,DB0011510017626_,0.846314379,0.351919914,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,cyanocobalamin,DB00115
,181961,DB00399,10027175,64,6928,39,4959,0.48266638,1.17459431,0.775380068,1.799878513,0.646993003,DB0039910027175_,0.435419798,0.16092282,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,zoledronic acid,DB00399
,181967,DB00399,10042682,44,6948,25,4973,0.392770169,1.259687809,0.753059774,2.150841318,0.562736503,DB0039910042682_,0.574943783,0.23086392,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,181990,DB00341,10022998,37,11368,22,5046,0.322116869,0.74651663,0.428451664,1.330013833,0.490475997,DB0034110022998_,0.712378937,-0.292337386,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,cetirizine,DB00341
,181996,DB01068,10029410,49,13714,14,6826,0.080514011,1.742045851,0.945639873,3.419254862,0.179277609,DB0106810029410_,1.718819789,0.555060199,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,clonazepam,DB01068
,182003,DB00215,10022086,95,11008,30,5246,0.054265931,1.509079507,0.9902728,2.360459524,0.132977206,DB0021510022086_,2.017577552,0.411499867,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,182021,DB00863,10016825,94,10579,36,5804,0.079681962,1.432514972,0.964561552,2.169183274,0.177886902,DB0086310016825_,1.726607314,0.359431621,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,ranitidine,DB00863
,182023,DB00338,10021518,41,33633,18,22254,0.182792049,1.507129167,0.846437692,2.787853953,0.327428718,DB0033810021518_,1.116484903,0.410206628,NA,10021518,Impaired gastric emptying,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,182027,DB00273,10046735,96,8385,8,2185,0.000545846,3.12682498,1.521619927,7.461300512,0.003318122,DB0027310046735_,5.708356205,1.140018106,female,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,topiramate,DB00273
,182048,DB00448,10005557,31,5114,20,3104,0.885066763,0.940797468,0.518405917,1.744816785,0.952134564,DB0044810005557_,0.049048906,-0.061027393,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,lansoprazole,DB00448
,182061,DB00046,10012378,38,5421,26,4666,0.38181698,1.257955763,0.74283627,2.161298023,0.551932209,DB0004610012378_,0.59433005,0.229487993,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,insulin lispro,DB00046
,182066,DB00959,10015090,48,8030,19,4983,0.102191728,1.567648495,0.903216861,2.827503233,0.214271662,DB0095910015090_,1.540510619,0.449576723,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,182072,DB00046,10020919,37,5422,40,4652,0.358859185,0.793658566,0.492659619,1.275562488,0.52863024,DB0004610020919_,0.637466071,-0.231101928,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,insulin lispro,DB00046
,182076,DB00787,10020919,35,16965,30,17218,0.535930739,1.184057936,0.705856631,1.997408399,0.692368991,DB0078710020919_,0.367636242,0.168947468,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,acyclovir,DB00787
,182093,DB00761,10027417,34,15273,25,8600,0.342289348,0.76582327,0.443303513,1.339902513,0.511604431,DB0076110027417_,0.670203549,-0.266803854,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,182124,DB00046,10043554,20,5439,37,4655,0.004967059,0.462656102,0.254051629,0.819356904,0.020353978,DB0004610043554_,3.894478927,-0.770771262,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,insulin lispro,DB00046
,182151,DB00316,10064990,30,65444,26,36927,0.125210024,0.651034233,0.372131205,1.14624436,0.2488767,DB0031610064990_,1.390797685,-0.429193054,NA,10064990,Skin abrasion,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,182265,DB00182,10040979,55,5139,31,2821,0.910097179,0.973910121,0.614473889,1.56902819,0.959542868,DB0018210040979_,0.041298287,-0.026436258,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amphetamine,DB00182
,182272,DB06204,10070863,68,744,12,367,0.000687784,2.79326861,1.476272395,5.742913741,0.00403356,DB0620410070863_,5.513105988,1.027212455,female,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,tapentadol,DB06204
,182278,DB00635,10036590,39,33014,47,23747,0.021063768,0.596885994,0.380028735,0.93278255,0.064412907,DB0063510036590_,2.74244124,-0.516029149,NA,10036590,Premature baby,10036585,"Pregnancy, puerperium and perinatal conditions",Preg,prednisone,DB00635
,182285,DB00959,10009887,33,8045,34,4968,0.043042575,0.599411707,0.359319519,0.998796826,0.111762728,DB0095910009887_,2.191377154,-0.511806593,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,182291,DB00959,10035226,39,8039,25,4977,0.897949707,0.965784927,0.569111999,1.66733232,0.956338178,DB0095910035226_,0.044643686,-0.034814113,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,methylprednisolone,DB00959
,182308,DB00126,10012601,43,10128,24,5921,0.899685674,1.047439049,0.620806978,1.806412388,0.956571579,DB0012610012601_,0.044399659,0.046348184,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,ascorbic acid,DB00126
,182310,DB00404,10021519,41,19851,12,9850,0.110104419,1.695311106,0.87365215,3.545277836,0.22621602,DB0040410021519_,1.486264894,0.527866267,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,182353,DB00285,10048010,127,10824,34,3684,0.23668518,1.271293591,0.863032671,1.918681656,0.39397568,DB0028510048010_,0.931466097,0.240034958,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,182354,DB00331,10048010,65,24881,41,20711,0.172465947,1.319652379,0.878815386,2.002126229,0.314079567,DB0033110048010_,1.158108928,0.277368353,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,182394,DB09072,10048908,39,6432,12,2523,0.534293574,1.274784169,0.652626717,2.678931557,0.690882134,DB0907210048908_,0.369786043,0.242776885,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,sodium oxybate,DB09072
,182410,DB00338,10004146,40,33634,32,22240,0.470082513,0.826553408,0.506127323,1.359759384,0.636339326,DB0033810004146_,0.452023327,-0.190490744,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,omeprazole,DB00338
,182420,DB01261,10025197,28,3753,35,3268,0.164198235,0.696657537,0.407256181,1.181587302,0.30302258,DB0126110025197_,1.193947955,-0.361461327,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,sitagliptin,DB01261
,182460,DB01202,10000059,35,6679,20,5698,0.175385205,1.492912373,0.837251301,2.732543025,0.317920079,DB0120210000059_,1.145955252,0.400728825,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,levetiracetam,DB01202
,182468,DB00335,10028836,45,8421,17,5448,0.067314635,1.712461349,0.959906226,3.194970604,0.15651866,DB0033510028836_,1.854580043,0.537931721,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,182478,DB01156,10028810,138,13484,46,6282,0.055795805,1.397661584,0.992954135,1.999024114,0.135713944,DB0115610028810_,1.99720596,0.334800543,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,bupropion,DB01156
,182479,DB00480,10028836,144,67284,90,67572,0.000392544,1.606833286,1.226036036,2.115433555,0.002523671,DB0048010028836_,5.982040722,0.474265339,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,182489,DB00264,10006002,104,29503,49,24843,0.000620979,1.787184854,1.260275866,2.565107285,0.003707116,DB0026410006002_,5.597501197,0.580641674,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,182501,DB00019,10010774,118,18894,38,9491,0.016937333,1.559840469,1.072951967,2.313502933,0.054239497,DB0001910010774_,2.914345912,0.444583552,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,pegfilgrastim,DB00019
,182517,DB00761,10024384,41,15266,22,8603,0.896233862,1.050234664,0.610681898,1.852564765,0.956301489,DB0076110024384_,0.044682051,0.049013629,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,potassium chloride,DB00761
,182553,DB00264,10074170,39,29568,30,24862,0.809125664,1.093126095,0.661575701,1.822678564,0.897075589,DB0026410074170_,0.108615152,0.089041569,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,182554,DB00338,10074170,73,33601,31,22241,0.044402048,1.558689395,1.010539112,2.456457797,0.114404681,DB0033810074170_,2.168013283,0.443845337,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,182587,DB00682,10001949,45,19414,34,16330,0.653067658,1.113249924,0.697025655,1.793108774,0.78720918,DB0068210001949_,0.239261272,0.107283597,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,182616,DB00193,10007554,58,19262,32,8670,0.362358489,0.815850439,0.520627694,1.299335823,0.532055575,DB0019310007554_,0.631007331,-0.203524226,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,tramadol,DB00193
,182618,DB00887,10007554,52,2289,56,1759,0.094442683,0.713635818,0.47707475,1.065805521,0.202423935,DB0088710007554_,1.597391092,-0.337382505,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,bumetanide,DB00887
,182640,DB00193,10017853,50,19270,9,8693,0.007196845,2.506129696,1.219442755,5.799464598,0.027370732,DB0019310017853_,3.598281021,0.918739609,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,182692,DB06228,10036653,36,15876,32,16044,0.628635315,1.136899483,0.686043492,1.891743906,0.76784714,DB0622810036653_,0.264164602,0.128304806,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,182693,DB00338,10040979,89,33585,73,22199,0.172757158,0.805862663,0.584409699,1.114231655,0.314473564,DB0033810040979_,1.156855265,-0.215841944,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,182799,DB00169,10015488,52,38639,15,18160,0.114879584,1.629290866,0.903017537,3.116996546,0.233466774,DB0016910015488_,1.454715507,0.488144869,NA,10015488,Essential hypertension,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,182800,DB00158,10016970,48,16767,11,8093,0.025177889,2.10616056,1.077860645,4.499761711,0.07389056,DB0015810016970_,2.605170193,0.74486665,NA,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,182811,DB00158,10039203,52,16763,12,8092,0.022218392,2.091775435,1.101123969,4.307889663,0.067116065,DB0015810039203_,2.701331841,0.738013196,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,182815,DB00169,10048049,71,38620,6,18169,5.47608018268475e-07,5.567289829,2.434234564,15.68396709,8.41501125997478e-06,DB0016910048049_,11.68549339,1.71690837,female,10048049,Wrist fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,182839,DB09053,10042772,28,2257,52,4000,0.907007074,0.95430008,0.57854458,1.544107673,0.958537515,DB0905310042772_,0.042346578,-0.046777107,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,ibrutinib,DB09053
,182847,DB00374,10005758,33,17683,21,5703,0.017079654,0.506797899,0.284334003,0.922612364,0.054588852,DB0037410005758_,2.907925597,-0.679642976,NA,10005758,Blood pressure systolic decreased,10022891,Investigations,Inv,treprostinil,DB00374
,182850,DB08931,10005758,53,6524,24,2422,0.440070661,0.819822639,0.496047171,1.391961718,0.608354756,DB0893110005758_,0.496997087,-0.198667256,NA,10005758,Blood pressure systolic decreased,10022891,Investigations,Inv,riociguat,DB08931
,182851,DB01046,10016256,68,817,13,315,0.019811254,2.015762195,1.084536456,4.035675215,0.061324713,DB0104610016256_,2.79157237,0.700997384,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lubiprostone,DB01046
,182852,DB06403,10016766,75,21396,13,6648,0.058495792,1.792473953,0.98656534,3.524390593,0.140679984,DB0640310016766_,1.961267583,0.583596762,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,182853,DB08931,10016766,85,6492,29,2417,0.750945859,1.09122562,0.706319696,1.73034454,0.859247587,DB0893110016766_,0.151698172,0.087301486,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,182856,DB08931,10028411,206,6371,74,2372,0.837818336,1.036461323,0.787399231,1.376712649,0.916554499,DB0893110028411_,0.087133749,0.035812337,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,riociguat,DB08931
,182865,DB00381,10017626,44,29316,21,22866,0.07910363,1.634233644,0.950849835,2.894333942,0.176873712,DB0038110017626_,1.732319294,0.491173975,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,amlodipine,DB00381
,182867,DB01069,10037377,55,6645,19,2376,1,1.035066567,0.603259463,1.850858715,1,DB0106910037377_,0,0.03446574,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,promethazine,DB01069
,182874,DB00761,10001497,47,15260,25,8600,0.902353926,1.059504035,0.638459196,1.797731179,0.957195726,DB0076110001497_,0.043747388,0.057800907,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,potassium chloride,DB00761
,182879,DB00184,10002855,39,1255,21,961,0.234596245,1.421867654,0.810016091,2.561945406,0.391449575,DB0018410002855_,0.937898573,0.351971257,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,nicotine,DB00184
,182881,DB01118,10002855,23,3040,35,4674,1,1.010357945,0.568804063,1.762918615,1,DB0111810002855_,0,0.010304669,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,amiodarone,DB01118
,182887,DB00987,10005364,23,2081,48,2880,0.115710244,0.663195344,0.383716205,1.115900014,0.234742699,DB0098710005364_,1.449265264,-0.410685696,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,cytarabine,DB00987
,182918,DB01076,10012218,37,25710,38,25545,0.908453641,0.967428223,0.598074393,1.563616295,0.959026229,DB0107610012218_,0.041836854,-0.033114044,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,182929,DB00343,10029354,30,8706,23,5072,0.32146336,0.759928755,0.426279331,1.371525376,0.489768386,DB0034310029354_,0.713822682,-0.274530594,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,diltiazem,DB00343
,182940,DB01076,10036790,93,25654,85,25498,0.599634707,1.08743816,0.801161035,1.477741689,0.744258289,DB0107610036790_,0.295367142,0.083824618,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,182951,DB01076,10038687,48,25699,48,25535,1,0.993618234,0.651676554,1.514999369,1,DB0107610038687_,0,-0.006402217,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,182964,DB01060,10061818,56,8531,35,5046,0.827979812,0.946388016,0.608584193,1.48996964,0.909558014,DB0106010061818_,0.094796497,-0.055102629,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,182969,DB00563,10006811,75,46571,12,15336,0.017591278,2.058004269,1.11119533,4.161041461,0.055901195,DB0056310006811_,2.884169516,0.721736712,NA,10006811,Bursitis,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,182970,DB00563,10050256,59,46587,13,15335,0.219290246,1.493877526,0.809763482,2.970175019,0.372629374,DB0056310050256_,0.98717099,0.401375106,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,183029,DB00193,10042209,89,19231,13,8689,2.26588413404103e-05,3.093043903,1.718336871,6.039424236,0.000222381,DB0019310042209_,8.411118636,1.129155688,female,10042209,Stress,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,183032,DB13961,10042209,56,9401,17,6397,0.002617872,2.241398783,1.282068257,4.118795675,0.012095404,DB1396110042209_,4.41492972,0.807100128,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,fish oil,DB13961
,183040,DB00394,10053762,44,1595,22,772,0.894708335,0.968066421,0.563223999,1.708725291,0.955976233,DB0039410053762_,0.045022227,-0.032454578,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,beclomethasone dipropionate,DB00394
,183103,DB00480,10060800,264,67164,108,67554,1.9977964221916e-16,2.458749511,1.95768489,3.105687014,1.43671898652001e-14,DB0048010060800_,31.87382927,0.899652892,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,lenalidomide,DB00480
,183153,DB00641,10048908,39,14085,12,12463,0.00067889,2.875484738,1.474308693,6.035595609,0.00399194,DB0064110048908_,5.523478039,1.056221265,female,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,simvastatin,DB00641
,183155,DB01047,10019211,47,740,19,461,0.151107454,1.540539934,0.87408,2.8162963,0.285416746,DB0104710019211_,1.2538049,0.432132961,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,fluocinonide,DB01047
,183157,DB00158,10040831,45,16770,15,8089,0.269313982,1.447028247,0.791114745,2.796568283,0.431852002,DB0015810040831_,0.839672337,0.369511969,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,183217,DB01590,10000496,50,4688,35,2832,0.501761655,0.863015271,0.547706559,1.37331863,0.663187262,DB0159010000496_,0.410697881,-0.147322892,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,everolimus,DB01590
,183218,DB00218,10033425,39,1403,20,930,0.419427275,1.292452033,0.730421677,2.354533542,0.588423413,DB0021810033425_,0.5303085,0.256541215,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,moxifloxacin,DB00218
,183223,DB00563,10011831,22,46624,32,15316,7.44553162841515e-08,0.225866574,0.12502075,0.401092662,1.3855277794895e-06,DB0056310011831_,13.48942942,-1.487810834,male,10011831,Cytomegalovirus infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,183227,DB00788,10013538,35,9321,23,5038,0.491711569,0.822523297,0.471874545,1.459727691,0.654776767,DB0078810013538_,0.423460916,-0.195378472,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,naproxen,DB00788
,183281,DB00264,10013916,46,29561,32,24860,0.428104265,1.208893536,0.753151443,1.962168457,0.596613149,DB0026410013916_,0.516486368,0.189705508,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,183352,DB00091,10002855,70,5440,10,2660,5.67712950353626e-05,3.42237623,1.751294542,7.458700042,0.000492161,DB0009110002855_,7.616703763,1.230335114,female,10002855,Anxiety,10037175,Psychiatric disorders,Psych,cyclosporine,DB00091
,183366,DB00787,10013538,84,16916,37,17211,1.46689951600398e-05,2.309920676,1.550409749,3.50068783,0.000152057,DB0078710013538_,8.791253822,0.837213185,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,acyclovir,DB00787
,183377,DB00455,10016288,40,9361,56,5062,4.57422933742747e-06,0.386278442,0.250439739,0.590976986,5.47387289479995e-05,DB0045510016288_,9.812939074,-0.951196816,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,loratadine,DB00455
,183379,DB00653,10016288,34,1058,46,776,0.00792149,0.542310637,0.334139312,0.872589491,0.029552672,DB0065310016288_,3.521581126,-0.61191631,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,magnesium sulfate,DB00653
,183380,DB01141,10016288,32,366,45,560,0.718060126,1.087945576,0.655877125,1.787068817,0.833519273,DB0114110016288_,0.182098454,0.084291126,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,micafungin,DB01141
,183419,DB11089,10007739,45,10130,27,8380,0.194074772,1.378717363,0.836340218,2.312961084,0.341804107,DB1108910007739_,1.073517493,0.32115362,NA,10007739,Cataract,10015919,Eye disorders,Eye,docusate,DB11089
,183453,DB01175,10017955,48,10676,33,4859,0.071952289,0.66202569,0.415681076,1.066083589,0.164694207,DB0117510017955_,1.803664816,-0.412450918,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,183457,DB01175,10005483,37,10687,20,4872,0.567772274,0.843403698,0.476419957,1.535309167,0.718825433,DB0117510005483_,0.330136742,-0.170309553,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,escitalopram,DB01175
,183469,DB00169,10019641,31,38660,28,18147,0.016640561,0.519677845,0.30153033,0.899480485,0.053471534,DB0016910019641_,2.928605841,-0.654546188,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,cholecalciferol,DB00169
,183489,DB00254,10010264,110,5825,44,3344,0.04294132,1.43514021,1.000198517,2.090518412,0.111582483,DB0025410010264_,2.192991207,0.361262552,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,183491,DB05259,10010264,112,11158,35,2693,0.20823559,0.77234046,0.522837763,1.166397116,0.359081053,DB0525910010264_,1.024207142,-0.258329816,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,183493,DB00695,10013754,49,28000,19,20509,0.019050591,1.888952968,1.091650872,3.398807448,0.059480507,DB0069510013754_,2.82210664,0.63602269,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,183532,DB00181,10049438,34,9822,19,5852,0.887544686,1.066180348,0.590504141,1.980570385,0.953356575,DB0018110049438_,0.047766285,0.064082494,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,183537,DB00181,10050256,35,9821,19,5852,0.780121206,1.09765484,0.610262449,2.033286701,0.880309353,DB0018110050256_,0.127481896,0.09317594,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,183574,DB00635,10001480,35,33018,28,23766,0.702568895,0.89973936,0.531589241,1.535817812,0.821576595,DB0063510001480_,0.196530108,-0.105650158,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,183593,DB00203,10013952,76,13802,17,8921,1.66934864256729e-05,2.889452277,1.690163163,5.220366164,0.000170277,DB0020310013952_,8.678082119,1.061066961,female,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,183594,DB00207,10013952,44,9036,16,5439,0.083993207,1.655241064,0.914651913,3.145823406,0.185059636,DB0020710013952_,1.68707715,0.503946656,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,183643,DB00697,10044565,100,5996,19,1787,0.078116389,1.568474366,0.950627832,2.721601006,0.175225234,DB0069710044565_,1.741683084,0.450103406,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,183649,DB00177,10022086,47,4753,16,2834,0.050644237,1.751379873,0.9730595,3.315618906,0.126172577,DB0017710022086_,2.070104652,0.560403976,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,183663,DB00502,10001540,19,1375,31,1841,0.565609242,0.820670939,0.436039602,1.506627072,0.717192355,DB0050210001540_,0.332411197,-0.197633056,NA,10001540,Akathisia,10029205,Nervous system disorders,Nerv,haloperidol,DB00502
,183701,DB00181,10051290,41,9815,17,5854,0.223360937,1.438426681,0.798513965,2.70303068,0.377680352,DB0018110051290_,0.97370707,0.363549934,NA,10051290,Central nervous system lesion,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,183704,DB00273,10022998,56,8425,20,2173,0.202391361,0.722208546,0.425594117,1.273553231,0.351784224,DB0027310022998_,1.044737292,-0.325441337,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,183705,DB01015,10013781,42,9845,11,9370,4.27281602823472e-05,3.633514633,1.837236132,7.829976153,0.000386147,DB0101510013781_,7.859291414,1.290200398,female,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,183706,DB01015,10013911,34,9853,18,9363,0.051047932,1.794890879,0.984852287,3.378532455,0.126979739,DB0101510013911_,2.063727744,0.584944229,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,183718,DB00341,10006002,39,11366,19,5049,0.77592878,0.911827887,0.513762291,1.672280985,0.877822795,DB0034110006002_,0.130310533,-0.092304027,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,183737,DB00863,10028391,69,10604,26,5814,0.107305784,1.455029226,0.913521979,2.383322635,0.22211541,DB0086310028391_,1.504558168,0.375025987,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,183739,DB00863,10033433,44,10629,16,5824,0.177229568,1.506785746,0.832724074,2.863358161,0.320324499,DB0086310033433_,1.138420737,0.409978737,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,183746,DB00399,10039101,55,6937,23,4975,0.028742901,1.714890904,1.034975557,2.927983168,0.081919996,DB0039910039101_,2.502012168,0.539349466,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zoledronic acid,DB00399
,183751,DB00341,10048439,43,11362,13,5055,0.248021479,1.471599137,0.775905774,2.985594771,0.407389132,DB0034110048439_,0.897986452,0.386349658,NA,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,183762,DB00863,10060800,70,10603,17,5823,0.001544366,2.26124809,1.315179784,4.103146511,0.007877673,DB0086310060800_,4.84372275,0.815916913,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,ranitidine,DB00863
,183772,DB00863,10070863,43,10630,33,5807,0.14966773,0.711868366,0.441240004,1.15790535,0.283512271,DB0086310070863_,1.260499872,-0.339862264,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,183791,DB00761,10019063,49,15258,41,8584,0.062125768,0.672405198,0.434566011,1.045061642,0.147413749,DB0076110019063_,1.91451203,-0.396894148,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,potassium chloride,DB00761
,183792,DB01098,10019063,31,8118,39,7170,0.150700242,0.702070194,0.42305852,1.15604602,0.284893259,DB0109810019063_,1.2556407,-0.353721889,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,rosuvastatin,DB01098
,183794,DB06228,10019063,20,15892,44,16032,0.003684568,0.458562563,0.255913493,0.794957673,0.015969802,DB0622810019063_,4.137055746,-0.779658546,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,rivaroxaban,DB06228
,183802,DB00338,10047461,122,33552,59,22213,0.048135157,1.368970328,0.994815318,1.902060855,0.121586835,DB0033810047461_,2.107126581,0.314058872,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,183808,DB00158,10061224,43,16772,20,8084,1,1.036263653,0.596132745,1.860697204,1,DB0015810061224_,0,0.035621603,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,183822,DB06643,10014184,138,52283,11,7504,0.062183103,1.800589807,0.974956749,3.692919679,0.147529819,DB0664310014184_,1.913724959,0.588114282,NA,10014184,Eczema,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,183829,DB00476,10013654,49,17208,34,6143,0.003832387,0.514468031,0.325152428,0.822651653,0.016477351,DB0047610013654_,4.105768504,-0.664621862,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,183867,DB00586,10042772,40,7069,19,2786,0.561898796,0.829757596,0.468511254,1.519600242,0.71422747,DB0058610042772_,0.336553782,-0.186621673,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,183869,DB06605,10028735,117,13956,42,12991,2.53024293292044e-08,2.592835229,1.806659974,3.785510325,5.19183727492692e-07,DB0660510028735_,14.47100801,0.95275196,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,183871,DB00285,10003246,45,10906,12,3706,0.542702891,1.274267433,0.662078301,2.649442899,0.69792776,DB0028510003246_,0.359639677,0.242371451,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,venlafaxine,DB00285
,183873,DB14500,10028372,72,7737,30,4043,0.345862201,1.254058672,0.807065142,1.992859357,0.515296661,DB1450010028372_,0.663012504,0.226385229,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,183874,DB06285,10028411,151,8699,8,1098,0.010573434,2.382281774,1.174107168,5.635260747,0.037207672,DB0628510028411_,3.2912403,0.868058757,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,teriparatide,DB06285
,183885,DB00047,10039906,48,9237,50,8468,0.544312844,0.880085032,0.579052384,1.336326878,0.699348084,DB0004710039906_,0.357606686,-0.127736749,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,183886,DB00264,10039906,175,29432,148,24744,0.955404888,0.994091439,0.793559788,1.246654643,0.993161739,DB0026410039906_,0.006861749,-0.005926086,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,183887,DB00285,10039906,155,10796,80,3638,0.003083336,0.65291335,0.493967805,0.868547949,0.0138348,DB0028510039906_,4.280568147,-0.426310854,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,183888,DB00343,10039906,46,8690,42,5053,0.035547611,0.636901491,0.409352131,0.993242329,0.096585586,DB0034310039906_,2.337325766,-0.45114028,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,183889,DB00575,10039906,80,5164,57,3772,0.930655767,1.025180356,0.718811512,1.470289067,0.97184406,DB0057510039906_,0.02855992,0.024868554,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,clonidine,DB00575
,183890,DB00641,10039906,82,14042,63,12412,0.452826061,1.150492069,0.817601933,1.625471283,0.620467437,DB0064110039906_,0.477282154,0.140189737,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,simvastatin,DB00641
,183892,DB00682,10039906,99,19360,85,16279,0.940886225,0.979347354,0.724940042,1.325458505,0.980113122,DB0068210039906_,0.020087283,-0.020868894,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,183893,DB00695,10039906,194,27855,110,20418,0.031283935,1.292755944,1.017140278,1.649942464,0.087548387,DB0069510039906_,2.435563645,0.25677633,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,183895,DB06403,10039906,62,21409,23,6638,0.445297731,0.83578867,0.510040345,1.414660105,0.613309841,DB0640310039906_,0.48888502,-0.179379485,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,183897,DB00273,10000059,69,8412,11,2182,0.163724795,1.627005115,0.853291569,3.415990802,0.302386485,DB0027310000059_,1.19604933,0.486740972,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,topiramate,DB00273
,183903,DB08889,10008479,35,3130,45,3840,0.91013289,0.954204236,0.593850853,1.521978512,0.959542868,DB0888910008479_,0.041298287,-0.046877547,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,183904,DB08889,10038695,23,3142,31,3854,0.784616187,0.910046375,0.505630745,1.615942591,0.883059927,DB0888910038695_,0.124362214,-0.094259719,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carfilzomib,DB08889
,183906,DB00207,10066901,23,9057,55,5400,4.70453981377551e-09,0.249356823,0.146068438,0.413076515,1.13709268050657e-07,DB0020710066901_,15.98962093,-1.388870384,male,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,183907,DB00512,10066901,60,4677,60,5038,0.713662599,1.077154401,0.738667952,1.570771945,0.83017443,DB0051210066901_,0.186119444,0.07432275,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,183926,DB00531,10061124,32,7220,22,6494,0.343055717,1.308257385,0.736048431,2.365785564,0.512385688,DB0053110061124_,0.66867764,0.268696011,NA,10061124,Enterococcal infection,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,183952,DB00343,10017944,35,8701,15,5080,0.378835941,1.362266297,0.724094751,2.687632477,0.548800061,DB0034310017944_,0.600021092,0.309149708,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,184024,DB01212,10020751,33,1986,24,1917,0.350434947,1.327130153,0.757781494,2.356174879,0.520111947,DB0121210020751_,0.653711207,0.283018831,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ceftriaxone,DB01212
,184027,DB00158,10005191,76,16739,16,8088,0.001637379,2.295054134,1.325371794,4.219857999,0.008252041,DB0015810005191_,4.797294768,0.830756431,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,184038,DB05679,10047899,91,6840,51,4858,0.198667807,1.2672547,0.887896087,1.826094289,0.347460463,DB0567910047899_,1.057104395,0.236852907,NA,10047899,Weight increased,10022891,Investigations,Inv,ustekinumab,DB05679
,184082,DB00169,10004146,72,38619,36,18139,0.757346113,0.939384291,0.620987683,1.44377178,0.864349901,DB0016910004146_,0.145777614,-0.062530628,NA,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cholecalciferol,DB00169
,184105,DB01076,10052428,26,25721,34,25549,0.303993959,0.759598645,0.437566133,1.304275694,0.470581932,DB0107610052428_,0.753785196,-0.274965084,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,184117,DB00399,10007739,65,6927,43,4955,0.768851544,1.081303211,0.723042043,1.63148969,0.873366444,DB0039910007739_,0.135400058,0.078166991,NA,10007739,Cataract,10015919,Eye disorders,Eye,zoledronic acid,DB00399
,184125,DB00540,10025482,62,2421,17,1074,0.084190649,1.617705223,0.928508404,2.966396078,0.185393643,DB0054010025482_,1.685273914,0.481008616,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,nortriptyline,DB00540
,184126,DB00198,10022000,131,1144,113,890,0.453586815,0.901938808,0.685007248,1.188887607,0.621142386,DB0019810022000_,0.476194938,-0.103208602,NA,10022000,Influenza,10021881,Infections and infestations,Infec,oseltamivir,DB00198
,184127,DB00281,10022000,125,11333,59,5612,0.813409147,1.049130184,0.762480902,1.457661919,0.899775248,DB0028110022000_,0.105610271,0.047961425,NA,10022000,Influenza,10021881,Infections and infestations,Infec,lidocaine,DB00281
,184128,DB00497,10022000,144,19123,113,16262,0.530694342,1.08370932,0.840405812,1.400208718,0.687682752,DB0049710022000_,0.374427664,0.080389712,NA,10022000,Influenza,10021881,Infections and infestations,Infec,oxycodone,DB00497
,184129,DB00697,10022000,59,6037,18,1788,0.891896542,0.97079308,0.562882425,1.753700731,0.955030252,DB0069710022000_,0.046012261,-0.029641933,NA,10022000,Influenza,10021881,Infections and infestations,Infec,tizanidine,DB00697
,184130,DB00788,10022000,86,9270,28,5033,0.017906365,1.667528835,1.075734026,2.657659038,0.056660517,DB0078810022000_,2.870677662,0.511342791,NA,10022000,Influenza,10021881,Infections and infestations,Infec,naproxen,DB00788
,184131,DB01015,10022000,96,9791,101,9280,0.47457544,0.900893263,0.673102251,1.205104053,0.640261533,DB0101510022000_,0.445878541,-0.104368493,NA,10022000,Influenza,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,184132,DB01137,10022000,76,7696,66,5527,0.267182712,0.826994622,0.585682553,1.170301711,0.429456221,DB0113710022000_,0.845235473,-0.189957087,NA,10022000,Influenza,10021881,Infections and infestations,Infec,levofloxacin,DB01137
,184133,DB09140,10022000,81,3660,27,1771,0.097713605,1.45154821,0.924884987,2.343586021,0.207442122,DB0914010022000_,1.57290291,0.372630718,NA,10022000,Influenza,10021881,Infections and infestations,Infec,oxygen,DB09140
,184136,DB01015,10025082,30,9857,22,9359,0.405501486,1.294721995,0.721696591,2.357421054,0.575121595,DB0101510025082_,0.55317379,0.258295997,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,184137,DB06228,10025082,38,15874,26,16050,0.133963774,1.477717278,0.873642585,2.536124535,0.261258884,DB0622810025082_,1.342243472,0.390498517,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,184159,DB00829,10019063,36,8016,32,4422,0.056364941,0.620600203,0.374131232,1.033747208,0.136750274,DB0082910019063_,1.989598831,-0.4770682,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,184163,DB09037,10013573,35,2491,44,2791,0.650760055,0.891281672,0.553038825,1.426708996,0.785255844,DB0903710013573_,0.241745698,-0.115094772,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pembrolizumab,DB09037
,184169,DB00230,10039073,144,19530,12,8639,5.11470805915927e-12,5.308223711,2.944843162,10.51830871,2.06671946710225e-10,DB0023010039073_,22.29988838,1.669257262,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,184175,DB00668,10070863,65,10026,58,4245,6.23790633083086e-05,0.474514524,0.32723665,0.689509007,0.000532521,DB0066810070863_,7.537887297,-0.745463052,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,epinephrine,DB00668
,184178,DB00252,10039906,211,2021,209,1699,0.121296201,0.848753669,0.689946951,1.044124849,0.243286581,DB0025210039906_,1.413515184,-0.163986278,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,phenytoin,DB00252
,184179,DB01202,10039906,941,5773,868,4850,0.070012385,0.910780358,0.823210877,1.007726655,0.161314476,DB0120210039906_,1.824399552,-0.093453511,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,184199,DB06168,10037660,95,514,62,338,1,1.007586519,0.702106345,1.453476472,1,DB0616810037660_,0,0.007557886,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,canakinumab,DB06168
,184210,DB00099,10021789,26,2359,34,1921,0.088600228,0.622798771,0.357530466,1.073218853,0.192937905,DB0009910021789_,1.645386877,-0.473531812,NA,10021789,Infection,10021881,Infections and infestations,Infec,filgrastim,DB00099
,184217,DB00582,10040047,32,1098,47,1527,0.907934531,0.946877127,0.580584242,1.526769915,0.958771936,DB0058210040047_,0.042102046,-0.054585944,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,voriconazole,DB00582
,184218,DB00928,10040047,39,796,76,1210,0.239487503,0.780140938,0.510652717,1.175738533,0.397319343,DB0092810040047_,0.923014932,-0.248280686,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,azacitidine,DB00928
,184247,DB00999,10039117,32,21398,34,12205,0.01429492,0.536821126,0.320555165,0.897128203,0.047384177,DB0099910039117_,3.049466932,-0.622090339,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,184248,DB01076,10039117,39,25708,51,25532,0.206530794,0.759477086,0.48717582,1.175747305,0.357101823,DB0107610039117_,1.02973432,-0.275125127,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,184269,DB01060,10003285,36,8551,25,5056,0.595646203,0.85145347,0.496528331,1.481599284,0.74122358,DB0106010003285_,0.299452972,-0.160810425,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,amoxicillin,DB01060
,184299,DB00158,10023230,65,16750,15,8089,0.008173649,2.092622753,1.179545532,3.953549151,0.030321693,DB0015810023230_,3.49589187,0.738418185,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,folic acid,DB00158
,184309,DB00310,10033371,36,908,22,759,0.284234966,1.367595251,0.775378298,2.462978349,0.448715681,DB0031010033371_,0.80136582,0.313053906,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,chlorthalidone,DB00310
,184311,DB01065,10035664,161,4170,135,2916,0.132220796,0.833982244,0.655943317,1.06159432,0.258973445,DB0106510035664_,1.351029753,-0.181543167,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,melatonin,DB01065
,184314,DB01222,10040979,39,9235,23,5382,1,0.98819446,0.574964896,1.735076145,1,DB0122210040979_,0,-0.011875778,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,184323,DB00563,10047924,99,46547,24,15324,0.209158564,1.357990274,0.862052797,2.219715029,0.360196652,DB0056310047924_,1.02110514,0.306005867,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,184371,DB01097,10042609,46,6219,19,1484,0.05663279,0.577768684,0.330741226,1.047457237,0.137191178,DB0109710042609_,1.986379865,-0.548581691,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,leflunomide,DB01097
,184376,DB00930,10053762,292,998,131,511,0.267937354,1.141199207,0.900132053,1.45170919,0.430327103,DB0093010053762_,0.843209656,0.132079645,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,colesevelam,DB00930
,184377,DB01307,10016173,80,2444,53,2016,0.250311836,1.245037863,0.864317398,1.806016118,0.410074893,DB0130710016173_,0.891415471,0.219165942,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin detemir,DB01307
,184383,DB00338,10041569,64,33610,40,22232,0.841307792,1.058357913,0.701761599,1.613365557,0.919014039,DB0033810041569_,0.084453881,0.056718568,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,184391,DB14500,10013971,69,7740,26,4047,0.160117396,1.387575576,0.870733572,2.274061007,0.297622923,DB1450010013971_,1.211927951,0.327558035,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,184402,DB00814,10010264,200,8087,57,3358,0.012384974,1.456958043,1.077270794,1.997096677,0.042212012,DB0081410010264_,3.165050455,0.37635073,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,184403,DB01273,10010264,51,1989,14,1261,0.004361843,2.309003401,1.25249519,4.536586379,0.018317787,DB0127310010264_,3.999882706,0.836816003,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,varenicline,DB01273
,184404,DB00814,10011224,159,8128,45,3370,0.024131199,1.464974058,1.043422991,2.092954868,0.071545719,DB0081410011224_,2.637418614,0.381837534,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,meloxicam,DB00814
,184408,DB00316,10076308,438,65036,201,36752,0.014744693,1.231458596,1.03917008,1.463254116,0.048652305,DB0031610076308_,3.023056084,0.208199317,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,184409,DB00814,10076308,63,8224,23,3392,0.721094297,1.129743018,0.689639129,1.911975803,0.835510066,DB0081410076308_,0.179712883,0.121990189,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,meloxicam,DB00814
,184416,DB00863,10051792,45,10628,28,5812,0.624146354,0.878889476,0.535843395,1.464702041,0.764045315,DB0086310051792_,0.269128179,-0.129096128,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,184434,DB06589,10025482,31,1999,42,2611,0.905821654,0.964068193,0.583645758,1.576880105,0.957917651,DB0658910025482_,0.042993464,-0.036593247,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,pazopanib,DB06589
,184476,DB00390,10069339,117,4028,101,3200,0.580039605,0.920301413,0.696157863,1.218324525,0.728688095,DB0039010069339_,0.316509492,-0.08305404,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,digoxin,DB00390
,184477,DB14726,10069339,53,1964,83,2765,0.596704973,0.898976667,0.621413201,1.290922514,0.742052384,DB1472610069339_,0.29833544,-0.106498199,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,dabigatran,DB14726
,184489,DB00654,10064355,34,3782,32,2566,0.207672708,0.720932861,0.43042253,1.210143937,0.358474939,DB0065410064355_,1.025896527,-0.327209266,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,latanoprost,DB00654
,184498,DB08895,10041349,119,27995,23,6623,0.453720338,1.224025477,0.777774079,2.006862892,0.62126112,DB0889510041349_,0.476003802,0.202144998,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,184499,DB00656,10076309,100,11913,52,6567,0.798640224,1.060090689,0.749789887,1.514195157,0.891257487,DB0065610076309_,0.115121907,0.05835446,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,184500,DB01267,10076309,86,2766,77,3638,0.016290201,1.468877635,1.062916182,2.03303103,0.052573876,DB0126710076309_,2.945535944,0.384498596,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,paliperidone,DB01267
,184505,DB06366,10012735,340,1398,6,77,0.003765539,3.119812558,1.353574925,8.837867879,0.016245745,DB0636610012735_,4.119924245,1.137772923,female,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pertuzumab,DB06366
,184506,DB06643,10037855,97,52324,13,7502,1,1.069812346,0.59676972,2.082355161,1,DB0664310037855_,0,0.067483255,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,184512,DB06643,10060933,189,52232,22,7493,0.4049669,1.232400894,0.789894131,2.014972167,0.574678781,DB0664310060933_,0.553944036,0.208964213,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,184518,DB01373,10012318,48,22672,10,7371,0.223825211,1.560487182,0.779095297,3.461370243,0.378295117,DB0137310012318_,0.972080654,0.444998069,NA,10012318,Dental caries,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,184530,DB01222,10006784,36,9238,15,5390,0.310385428,1.400272359,0.746919,2.755509947,0.477816683,DB0122210006784_,0.738528127,0.33666676,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,184545,DB01156,10039906,307,13315,182,6146,0.009084613,0.778646375,0.644389493,0.942920031,0.032975082,DB0115610039906_,3.412003106,-0.250198284,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,bupropion,DB01156
,184548,DB01611,10017885,57,11856,12,2349,0.870696089,0.941098838,0.49831236,1.93019948,0.942713132,DB0161110017885_,0.058993251,-0.06070711,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,184554,DB06643,10005393,40,52381,11,7504,0.057568133,0.520915389,0.262181875,1.126269596,0.13887238,DB0664310005393_,1.974199896,-0.652167651,NA,10005393,Blood calcium abnormal,10022891,Investigations,Inv,denosumab,DB06643
,184555,DB08910,10041569,39,16705,38,17450,0.819756873,1.072052551,0.667630876,1.722924494,0.903981767,DB0891010041569_,0.100946088,0.069575083,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pomalidomide,DB08910
,184557,DB06643,10013082,94,52327,8,7507,0.177982878,1.6856791,0.820870851,4.020201028,0.321299403,DB0664310013082_,1.135381871,0.522168509,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,184583,DB00776,10039906,165,1740,175,1164,7.18535539161247e-05,0.63085008,0.500194574,0.79527182,0.000600054,DB0077610039906_,7.418490536,-0.460687036,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,oxcarbazepine,DB00776
,184584,DB00829,10039906,167,7885,119,4335,0.033748453,0.771572793,0.604372351,0.987447629,0.092887759,DB0082910039906_,2.376363406,-0.259324258,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,184585,DB01080,10039906,414,1645,443,1669,0.49055212,0.948159146,0.813445569,1.105114552,0.653812463,DB0108010039906_,0.424934723,-0.053232915,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,vigabatrin,DB01080
,184586,DB06218,10039906,396,1298,366,1070,0.181107649,0.891948374,0.754810344,1.054104945,0.325222522,DB0621810039906_,1.123245648,-0.114347025,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,lacosamide,DB06218
,184589,DB01202,10049848,60,6654,50,5668,0.923790374,1.022182786,0.689333776,1.521430094,0.966829343,DB0120210049848_,0.03373328,0.021940327,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,184595,DB00999,10038743,39,21391,11,12228,0.038789369,2.026691478,1.017487468,4.389249105,0.103235577,DB0099910038743_,2.270741743,0.70640465,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,184607,DB00776,10037844,54,1851,36,1303,0.828968989,1.055906981,0.675530281,1.667845525,0.910150159,DB0077610037844_,0.094145683,0.054400095,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,oxcarbazepine,DB00776
,184613,DB00776,10047895,34,1871,27,1312,0.694098837,0.883065585,0.5143639,1.529721078,0.815819199,DB0077610047895_,0.203562519,-0.124355806,NA,10047895,Weight decreased,10022891,Investigations,Inv,oxcarbazepine,DB00776
,184614,DB00451,10069339,495,46776,346,15073,3.40970890783646e-26,0.461003442,0.400501581,0.531072491,5.70854768423447e-24,DB0045110069339_,53.52007759,-0.77434977,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,184631,DB00433,10020751,63,7593,25,5995,0.003409697,1.989531525,1.232058778,3.30490939,0.015002325,DB0043310020751_,4.199550108,0.687899196,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,prochlorperazine,DB00433
,184636,DB00186,10056819,42,16859,21,9987,0.602345179,1.18479755,0.685548924,2.107294222,0.746347516,DB0018610056819_,0.292563949,0.169571916,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,184645,DB00264,10024670,32,29575,22,24870,0.496977475,1.223140644,0.688772181,2.210092402,0.659117661,DB0026410024670_,0.416853216,0.20142185,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,metoprolol,DB00264
,184646,DB00331,10024670,34,24912,30,20722,0.900161022,0.942743417,0.559671407,1.59532854,0.956646281,DB0033110024670_,0.044321568,-0.058961125,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,metformin,DB00331
,184652,DB06210,10035528,146,1314,102,959,0.786573911,1.044652336,0.794219394,1.377983909,0.884231257,DB0621010035528_,0.123036647,0.043684137,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,eltrombopag,DB06210
,184662,DB09153,10016825,54,7745,36,5663,0.748272869,1.096789504,0.705197995,1.724045128,0.857064835,DB0915310016825_,0.15424171,0.09238728,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,sodium chloride,DB09153
,184668,DB00175,10040047,71,8060,58,6048,0.655533253,0.91856518,0.639041107,1.32497596,0.789149811,DB0017510040047_,0.236799102,-0.084942414,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,pravastatin,DB00175
,184695,DB01141,10013709,30,368,68,537,0.064216791,0.644053816,0.396138624,1.02647487,0.151032423,DB0114110013709_,1.890260741,-0.439972991,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,micafungin,DB01141
,184696,DB01413,10013709,56,1164,89,1570,0.388657534,0.848730746,0.591109076,1.210085709,0.558595389,DB0141310013709_,0.58232988,-0.164013285,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cefepime,DB01413
,184701,DB00582,10017533,20,1110,34,1540,0.577586243,0.816170774,0.442631351,1.468058693,0.726593021,DB0058210017533_,0.319388765,-0.203131664,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,voriconazole,DB00582
,184702,DB00635,10017533,146,32907,81,23713,0.059373565,1.298864425,0.982794517,1.726767485,0.142328695,DB0063510017533_,1.94961614,0.261490364,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,184706,DB00864,10017533,29,6840,47,8345,0.24890109,0.752798755,0.456374236,1.222641444,0.408349103,DB0086410017533_,0.895632826,-0.283957344,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,184709,DB01015,10017533,42,9845,24,9357,0.048519416,1.663204489,0.983336961,2.873843493,0.12229303,DB0101510017533_,2.10133523,0.508746156,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,184745,DB00688,10033661,54,6436,83,5295,0.000369156,0.535296632,0.37200355,0.764736291,0.002398829,DB0068810033661_,6.03277442,-0.624934233,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,mycophenolate mofetil,DB00688
,184753,DB00959,10035598,44,8034,50,4952,0.003800397,0.542462036,0.352773175,0.83148438,0.016365241,DB0095910035598_,4.11259565,-0.611637176,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,184761,DB00512,10038687,30,4707,37,5061,0.624610467,0.871802154,0.519250168,1.452855896,0.764374195,DB0051210038687_,0.268697825,-0.137192768,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vancomycin,DB00512
,184764,DB01015,10038687,24,9863,40,9341,0.032571167,0.568265834,0.32738529,0.966792412,0.090357058,DB0101510038687_,2.403986147,-0.565165953,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,184769,DB00582,10038695,47,1083,65,1509,1,1.007498687,0.671397791,1.502188243,1,DB0058210038695_,0,0.007470712,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,voriconazole,DB00582
,184802,DB00512,10059866,42,4695,93,5005,5.90547126858492e-05,0.481467906,0.325436514,0.701982433,0.000509186,DB0051210059866_,7.582697442,-0.730915703,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,184807,DB01015,10059866,21,9866,33,9348,0.076329653,0.602972581,0.331258947,1.074603277,0.172017399,DB0101510059866_,1.760159652,-0.505883555,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,184816,DB00635,10067472,27,33026,37,23757,0.011016396,0.524943101,0.307303983,0.886050846,0.038447317,DB0063510067472_,3.258466352,-0.644465401,NA,10067472,Organising pneumonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,184843,DB00480,10037868,34,67394,45,67617,0.260342502,0.75805949,0.470832497,1.210293777,0.421749879,DB0048010037868_,0.863342845,-0.276993413,NA,10037868,Rash maculo-papular,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,184848,DB00497,10039906,122,19145,84,16291,0.141296689,1.23586193,0.927643293,1.653112145,0.27169856,DB0049710039906_,1.303062063,0.211768646,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,184852,DB00619,10042682,59,2840,20,2474,0.000148351,2.569296925,1.51963094,4.518542235,0.00111571,DB0061910042682_,6.79826452,0.943632291,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,184857,DB09270,10011906,48,3066,94,2274,2.50784335189298e-08,0.378797373,0.260626795,0.54438547,5.1498955081646e-07,DB0927010011906_,14.47911923,-0.970753851,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,184872,DB06228,10020751,84,15828,43,16033,0.000239041,1.978736483,1.353517798,2.930029357,0.001671949,DB0622810020751_,6.393765387,0.682458501,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,rivaroxaban,DB06228
,184919,DB13961,10037423,36,9421,21,6393,0.685375461,1.163251439,0.660330474,2.099329369,0.810012993,DB1396110037423_,0.21070499,0.151219049,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,184925,DB00814,10005191,34,8253,21,3394,0.140008142,0.665849278,0.3748322,1.209187265,0.269842069,DB0081410005191_,1.309918419,-0.406691943,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,meloxicam,DB00814
,184926,DB00281,10012378,112,11346,31,5640,0.003133034,1.795888161,1.195546965,2.770537449,0.014016136,DB0028110012378_,4.267546065,0.585499697,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,lidocaine,DB00281
,184928,DB00620,10012378,95,4733,35,3097,0.003619887,1.775948174,1.190230885,2.70448803,0.015741375,DB0062010012378_,4.151462673,0.574334463,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,triamcinolone,DB00620
,184932,DB00530,10012432,31,1777,29,1239,0.289769415,0.745411552,0.432106093,1.289138864,0.454952607,DB0053010012432_,0.787562027,-0.293818794,NA,10012432,Dermatitis acneiform,10040785,Skin and subcutaneous tissue disorders,Skin,erlotinib,DB00530
,184939,DB00530,10013786,90,1718,19,1249,8.81091732642305e-08,3.442501136,2.068842164,6.013640635,1.61502762848696e-06,DB0053010013786_,13.33615849,1.236198282,female,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,erlotinib,DB00530
,184941,DB00814,10013786,50,8237,19,3396,0.894393144,1.084954692,0.627331672,1.951717869,0.955931269,DB0081410013786_,0.045069263,0.081538228,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,meloxicam,DB00814
,184947,DB00620,10037087,148,4680,86,3046,0.4550687,1.120087657,0.849381645,1.484584618,0.622620867,DB0062010037087_,0.473817506,0.113406947,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,triamcinolone,DB00620
,184958,DB09027,10008479,37,5142,40,7112,0.298255515,1.279347867,0.79437991,2.055577453,0.464200267,DB0902710008479_,0.76743921,0.246350469,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,184959,DB09027,10012174,27,5152,37,7115,1,1.007769564,0.589332607,1.703030589,1,DB0902710012174_,0,0.007739536,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,ledipasvir,DB09027
,184960,DB09027,10012735,319,4860,335,6817,0.000336746,1.335631527,1.13702256,1.568777412,0.002220893,DB0902710012735_,6.109846095,0.289404234,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ledipasvir,DB09027
,184965,DB09027,10047700,126,5053,127,7025,0.012014433,1.379258975,1.066393339,1.783774131,0.041186746,DB0902710047700_,3.189638778,0.32154638,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ledipasvir,DB09027
,184970,DB00264,10069339,480,29127,635,24257,3.10125085799249e-14,0.629532677,0.55729729,0.710759744,1.70358158416578e-12,DB0026410069339_,27.09828827,-0.462777518,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,184971,DB00736,10069339,409,10182,308,5245,1.31066572655756e-06,0.684037865,0.586319284,0.798717142,1.82279622341616e-05,DB0073610069339_,10.91255376,-0.379742004,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,esomeprazole,DB00736
,184972,DB00758,10069339,143,8157,248,9826,0.000565193,0.694608399,0.560189061,0.858656215,0.003416375,DB0075810069339_,5.679175269,-0.364407047,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,clopidogrel,DB00758
,184973,DB01076,10069339,384,25363,608,24975,2.74934619299877e-13,0.621927057,0.545235315,0.708711986,1.33951000339152e-11,DB0107610069339_,25.03613214,-0.474932464,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,184974,DB01394,10069339,36,1404,87,1916,0.003846405,0.564783294,0.369568615,0.84765236,0.016528159,DB0139410069339_,4.102689767,-0.571313172,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,colchicine,DB01394
,184975,DB04854,10069339,23,758,30,1456,0.187976899,1.472436698,0.810581706,2.642353995,0.334018778,DB0485410069339_,1.096558065,0.386918646,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,febuxostat,DB04854
,184976,DB09027,10069339,37,5142,97,7055,0.000575815,0.523382007,0.347673462,0.773196056,0.003471797,DB0902710069339_,5.663082942,-0.647443666,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ledipasvir,DB09027
,184978,DB00924,10001497,57,10105,26,4225,0.717933633,0.916634551,0.566116622,1.521033087,0.833478562,DB0092410001497_,0.182147298,-0.087046413,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,184983,DB00158,10017413,80,16735,72,8032,0.000166602,0.533270968,0.382536994,0.744601358,0.001235128,DB0015810017413_,6.696580636,-0.628725601,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,folic acid,DB00158
,184985,DB00787,10017413,286,16714,237,17011,0.021857915,1.228184644,1.028903251,1.467163582,0.066293809,DB0078710017413_,2.713658772,0.20553718,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,acyclovir,DB00787
,184991,DB00047,10065154,43,9242,45,8473,0.593085298,0.876053896,0.562505696,1.362746762,0.739243979,DB0004710065154_,0.302127265,-0.132327665,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,insulin glargine,DB00047
,184993,DB00230,10065154,47,19627,20,8631,1,1.033445462,0.600113942,1.842365964,1,DB0023010065154_,0,0.032898329,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,pregabalin,DB00230
,184998,DB00905,10015946,270,2448,23,902,2.2523155956446e-15,4.324692725,2.7990588,6.987207584,1.44395403491508e-13,DB0090510015946_,29.566221,1.464341092,female,10015946,Eye irritation,10015919,Eye disorders,Eye,bimatoprost,DB00905
,185015,DB09037,10037087,37,2489,65,2770,0.027676057,0.633550044,0.409723423,0.966800426,0.079521772,DB0903710037087_,2.531724432,-0.456416287,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,pembrolizumab,DB09037
,185021,DB00374,10022067,65,17651,16,5708,0.366488142,1.313708857,0.750715564,2.43474475,0.536082852,DB0037410022067_,0.623466556,0.272854325,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,185024,DB00820,10044565,79,11836,37,5779,0.921023313,1.042486483,0.6960459,1.58706211,0.965007709,DB0082010044565_,0.035619189,0.041608709,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,185027,DB00927,10001053,61,7436,39,4977,0.918467356,1.046873105,0.687995885,1.609925449,0.963960728,DB0092710001053_,0.036704724,0.045807726,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,185056,DB00381,10069339,569,28791,664,22223,9.38472206454135e-13,0.661455432,0.589529135,0.741968719,4.21670802506785e-11,DB0038110069339_,23.88938129,-0.413312671,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,185057,DB00678,10069339,247,15352,251,10473,1.16308742669597e-05,0.671346055,0.559866208,0.804904715,0.000123898,DB0067810069339_,8.996054479,-0.398470545,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,losartan,DB00678
,185058,DB00927,10069339,200,7297,192,4824,0.000297162,0.688677283,0.560152023,0.846825859,0.002001767,DB0092710069339_,6.213724802,-0.372982502,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,famotidine,DB00927
,185059,DB08882,10069339,20,977,32,961,0.093420417,0.614916891,0.330797944,1.117533106,0.200797138,DB0888210069339_,1.605460146,-0.486268157,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,linagliptin,DB08882
,185091,DB00181,10051118,38,9818,21,5850,0.892892469,1.07819851,0.616214271,1.935814324,0.955415161,DB0018110051118_,0.045609309,0.075291602,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,185096,DB05679,10011906,42,6889,62,4847,0.000195902,0.476646768,0.313732874,0.717931019,0.001416195,DB0567910011906_,6.559781423,-0.740979592,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,185098,DB00921,10000059,43,5802,40,4863,0.659209109,0.901030629,0.570999727,1.424694275,0.79180136,DB0092110000059_,0.233444727,-0.104216028,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,buprenorphine,DB00921
,185107,DB00349,10039906,274,748,264,680,0.577822628,0.943577798,0.769909168,1.15642329,0.72673658,DB0034910039906_,0.319191205,-0.058076461,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,clobazam,DB00349
,185108,DB00555,10039906,434,6613,301,3185,4.18091167166272e-06,0.694444232,0.594400035,0.812110873,5.0479346327209e-05,DB0055510039906_,9.893946289,-0.36464342,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,185109,DB00909,10039906,129,691,91,390,0.145810515,0.800235045,0.589560369,1.089116795,0.278190418,DB0090910039906_,1.279449442,-0.222849788,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,zonisamide,DB00909
,185112,DB00661,10076309,38,3490,13,1582,0.448733423,1.324894933,0.68807352,2.718565859,0.616327003,DB0066110076309_,0.483977607,0.28133316,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,verapamil,DB00661
,185120,DB00773,10008531,21,2302,45,2782,0.033767366,0.564034539,0.318154481,0.969968322,0.092914118,DB0077310008531_,2.376079676,-0.572639789,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,etoposide,DB00773
,185128,DB00669,10071134,905,5472,198,899,0.001237505,0.750956929,0.632739844,0.894117558,0.006558691,DB0066910071134_,5.026964272,-0.28640698,NA,10071134,Product physical issue,10077536,Product issues,Prod,sumatriptan,DB00669
,185136,DB00158,10042458,51,16764,21,8083,0.615097873,1.170950307,0.691377306,2.051065702,0.756544533,DB0015810042458_,0.278993881,0.157815648,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,folic acid,DB00158
,185137,DB00563,10042458,44,46602,9,15339,0.206843407,1.609109982,0.775080001,3.749755881,0.357500506,DB0056310042458_,1.028618502,0.47568122,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,185141,DB08820,10011906,35,4366,51,3494,0.006323813,0.549258472,0.345836715,0.863352791,0.024701351,DB0882010011906_,3.70089735,-0.599186144,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ivacaftor,DB08820
,185142,DB08820,10035664,178,4223,158,3387,0.370054989,0.90357242,0.721615714,1.132205364,0.539708441,DB0882010035664_,0.616726209,-0.101399017,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ivacaftor,DB08820
,185152,DB00370,10007617,82,4459,48,3615,0.075887147,1.384923811,0.955549351,2.026718371,0.17130775,DB0037010007617_,1.764293633,0.325645128,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,mirtazapine,DB00370
,185166,DB01060,10044034,52,8535,48,5033,0.028853493,0.638879311,0.422459362,0.967811865,0.082164747,DB0106010044034_,2.499028935,-0.448039713,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,185184,DB00904,10000880,50,23019,53,14403,0.008203178,0.590314325,0.392713864,0.88613822,0.030407634,DB0090410000880_,3.493061575,-0.527100129,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ondansetron,DB00904
,185203,DB00390,10005734,31,4114,35,3266,0.17129869,0.703187861,0.418341798,1.17685883,0.312625313,DB0039010005734_,1.162749889,-0.352131195,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,digoxin,DB00390
,185206,DB00524,10010774,37,1540,24,1320,0.302394403,1.321302189,0.765148234,2.321644526,0.468782217,DB0052410010774_,0.757616974,0.278617757,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,metolazone,DB00524
,185208,DB08890,10012378,50,1897,8,551,0.149487632,1.814934157,0.847067001,4.460180037,0.28324256,DB0889010012378_,1.261451647,0.59604919,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,linaclotide,DB08890
,185213,DB00695,10013496,47,28002,22,20506,0.088122075,1.564452621,0.923942176,2.726968821,0.192125514,DB0069510013496_,1.649606399,0.447536,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,185218,DB00203,10013786,39,13839,18,8920,0.277876308,1.396516361,0.779537951,2.595306141,0.441554802,DB0020310013786_,0.817453139,0.333980822,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,sildenafil,DB00203
,185224,DB08932,10013786,63,19380,19,6578,0.704662597,1.125445685,0.664330853,1.992679268,0.822904333,DB0893210013786_,0.194915327,0.118179121,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,macitentan,DB08932
,185230,DB08931,10017577,105,6472,34,2412,0.563922575,1.150909352,0.772648445,1.753195159,0.715796064,DB0893110017577_,0.33435998,0.140552371,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,185233,DB08932,10018836,106,19337,38,6559,0.773384079,0.946171211,0.646778941,1.410791974,0.876186393,DB0893210018836_,0.132176433,-0.055331743,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,185234,DB00390,10027175,58,4087,27,3274,0.020808888,1.720707919,1.069556949,2.833010582,0.063763304,DB0039010027175_,2.752577429,0.542735787,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,digoxin,DB00390
,185237,DB08931,10027175,89,6488,9,2437,1.68793707577589e-05,3.714260314,1.866947505,8.402960863,0.000171933,DB0893110027175_,8.668403091,1.31217955,female,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,185238,DB08931,10028334,146,6431,42,2404,0.158375774,1.299390604,0.913031727,1.884095774,0.295314952,DB0893110028334_,1.219712858,0.261895389,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,riociguat,DB08931
,185255,DB00390,10047513,36,4109,16,3285,0.050510851,1.798646315,0.97101007,3.477900975,0.125940118,DB0039010047513_,2.071948739,0.587034335,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,digoxin,DB00390
,185290,DB00678,10003119,31,15568,25,10699,0.587141294,0.85219027,0.486657929,1.506300638,0.734285674,DB0067810003119_,0.308857124,-0.159945455,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,losartan,DB00678
,185321,DB00582,10034972,43,1087,41,1533,0.091356362,1.478849865,0.934291981,2.343936648,0.197450839,DB0058210034972_,1.622265641,0.391264668,NA,10034972,Photosensitivity reaction,10040785,Skin and subcutaneous tissue disorders,Skin,voriconazole,DB00582
,185341,DB01307,10022086,39,2485,17,2052,0.030081914,1.894103999,1.04307013,3.582038544,0.084875816,DB0130710022086_,2.466566081,0.638745903,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,insulin detemir,DB01307
,185342,DB01307,10044565,32,2492,25,2044,0.894112324,1.049887013,0.600654699,1.854392887,0.955860142,DB0130710044565_,0.045143671,0.048682552,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,insulin detemir,DB01307
,185346,DB01115,10021789,40,3560,21,2247,0.597327493,1.202175951,0.690090888,2.152179558,0.742483875,DB0111510021789_,0.297754126,0.184133207,NA,10021789,Infection,10021881,Infections and infestations,Infec,nifedipine,DB01115
,185384,DB00321,10020937,116,7331,36,2814,0.31486656,1.236809742,0.842024833,1.856155887,0.482440543,DB0032110020937_,0.728897592,0.212535275,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,185392,DB00656,10005557,70,11943,30,6589,0.294686133,1.28731693,0.8272032,2.048002687,0.460553855,DB0065610005557_,0.775325482,0.252560153,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,trazodone,DB00656
,185407,DB00158,10057362,59,16756,26,8078,0.816664964,1.093980632,0.678246113,1.809769132,0.901858608,DB0015810057362_,0.103297525,0.089823,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,185410,DB00563,10057362,109,46537,53,15295,0.022420767,0.675934971,0.482262237,0.957660152,0.067556583,DB0056310057362_,2.694789767,-0.391658404,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,185411,DB00656,10057362,41,11972,18,6601,0.496307662,1.255922814,0.704888886,2.324466144,0.658544986,DB0065610057362_,0.417722444,0.227870612,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,185415,DB00421,10038063,37,8866,21,5231,1,1.039535402,0.59208605,1.871282255,1,DB0042110038063_,0,0.038773884,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,spironolactone,DB00421
,185431,DB00455,10030095,56,9345,22,5096,0.234412681,1.388053259,0.832918552,2.390365124,0.391320524,DB0045510030095_,0.9382283,0.327902232,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,185441,DB13961,10030095,69,9388,30,6384,0.040212486,1.563995523,1.003703759,2.490896654,0.106080408,DB1396110030095_,2.243557908,0.44724378,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,185444,DB00656,10022004,80,11933,20,6599,0.001051895,2.211932964,1.340385699,3.816777344,0.005747649,DB0065610022004_,5.158964385,0.793866778,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,185448,DB00656,10027599,126,11887,13,6606,1.52241908155945e-12,5.386811047,3.035476243,10.40404482,6.63628284557051e-11,DB0065610027599_,23.43588403,1.683953567,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,185452,DB00813,10006784,39,10533,17,10151,0.006887776,2.210708709,1.220794337,4.17075716,0.026461049,DB0081310006784_,3.632081481,0.793313147,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,185484,DB00213,10016454,55,18840,17,13404,0.001740893,2.30172565,1.315342425,4.232529791,0.008668189,DB0021310016454_,4.748095342,0.833659124,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,185489,DB06643,10050819,63,52358,9,7506,1,1.003514233,0.496159435,2.29638606,1,DB0664310050819_,0,0.003508073,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,185505,DB06643,10049816,52,52369,9,7506,0.562034064,0.828127255,0.404181133,1.912310083,0.714334853,DB0664310049816_,0.336403444,-0.188588447,NA,10049816,Muscle tightness,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,185508,DB00287,10019211,43,1358,17,800,0.177391767,1.489827425,0.825647884,2.805977529,0.32051848,DB0028710019211_,1.137815343,0.398660291,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,travoprost,DB00287
,185521,DB00684,10037844,34,2758,23,2325,0.426723391,1.2461232,0.710612196,2.222465234,0.595414817,DB0068410037844_,0.518496945,0.220037292,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,tobramycin,DB00684
,185531,DB00484,10052140,54,2453,34,1746,0.662197296,1.13040665,0.719197734,1.799067727,0.794044658,DB0048410052140_,0.230615575,0.122577436,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,brimonidine,DB00484
,185534,DB06643,10062132,299,52122,40,7475,0.742354333,1.072024759,0.768134695,1.532390735,0.852365781,DB0664310062132_,0.159739524,0.069549159,NA,10062132,Tooth extraction,10042613,Surgical and medical procedures,Surg,denosumab,DB06643
,185535,DB06643,10064143,91,52330,8,7507,0.223368077,1.631788022,0.793557023,3.895302549,0.377680352,DB0664310064143_,0.97370707,0.48967636,NA,10064143,Dental implantation,10042613,Surgical and medical procedures,Surg,denosumab,DB06643
,185536,DB08932,10008611,70,19373,17,6580,0.265864565,1.398507767,0.813644293,2.537124903,0.427965588,DB0893210008611_,0.848712488,0.335405787,NA,10008611,Cholecystectomy,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,185538,DB00316,10021654,58,65416,27,36926,0.431363517,1.212545824,0.755517671,1.991927853,0.599787877,DB0031610021654_,0.511179224,0.192722137,NA,10021654,Increased appetite,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,185543,DB00198,10003549,35,1240,25,978,0.792497609,1.104182936,0.637423359,1.938617904,0.887531177,DB0019810003549_,0.119311629,0.099105637,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,oseltamivir,DB00198
,185550,DB00198,10016256,74,1201,29,974,0.000776971,2.068762223,1.317528076,3.32567003,0.004463488,DB0019810016256_,5.411824707,0.726950469,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,oseltamivir,DB00198
,185567,DB00443,10003549,30,2116,29,1161,0.038750752,0.567669487,0.32741788,0.985566011,0.10314045,DB0044310003549_,2.271663624,-0.566215919,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,betamethasone,DB00443
,185568,DB00653,10003549,33,1059,38,784,0.068187128,0.64307421,0.387045812,1.063541851,0.158037093,DB0065310003549_,1.844925508,-0.441495149,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,magnesium sulfate,DB00653
,185577,DB06724,10020947,91,7838,33,3886,0.149664759,1.367160486,0.90692743,2.106659136,0.283512271,DB0672410020947_,1.260499872,0.312735951,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,calcium carbonate,DB06724
,185604,DB00213,10037884,72,18823,54,13367,0.78616355,0.946875802,0.655652803,1.374543742,0.883958973,DB0021310037884_,0.123344628,-0.054587343,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,185606,DB00787,10037884,121,16879,95,17153,0.065204687,1.294346561,0.980350069,1.713088906,0.152795329,DB0078710037884_,1.878655971,0.258005982,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,185614,DB00047,10061818,44,9241,67,8451,0.009787577,0.600597187,0.400489372,0.892764379,0.034990338,DB0004710061818_,3.352683323,-0.509830808,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,185626,DB13961,10035226,56,9401,61,6353,0.010583751,0.620424054,0.423211461,0.908022762,0.037240834,DB1396110035226_,3.290349443,-0.477352077,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fish oil,DB13961
,185632,DB09037,10033371,47,2479,63,2772,0.385526009,0.834236103,0.557002049,1.241909278,0.555658889,DB0903710033371_,0.587600682,-0.181238819,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,pembrolizumab,DB09037
,185633,DB09037,10035664,56,2470,78,2757,0.220734218,0.80140422,0.555619226,1.14954805,0.374407055,DB0903710035664_,0.98241169,-0.221389815,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pembrolizumab,DB09037
,185643,DB00334,10002034,35,2814,27,2785,0.372153092,1.282877723,0.75217377,2.210146578,0.541835392,DB0033410002034_,0.612793029,0.249105775,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,olanzapine,DB00334
,185644,DB00472,10002034,91,10668,40,4272,0.627878006,0.911033957,0.620462405,1.358980301,0.767207,DB0047210002034_,0.264998631,-0.093175108,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,fluoxetine,DB00472
,185650,DB00186,10029282,36,16865,58,9950,1.64710577038974e-06,0.366207303,0.234491774,0.565028022,2.23858196353125e-05,DB0018610029282_,10.70708285,-1.004555703,male,10029282,Neuroleptic malignant syndrome,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,185661,DB00186,10039906,255,16646,199,9809,0.003814137,0.755121203,0.623742568,0.915126535,0.016412311,DB0018610039906_,4.109723572,-0.280877009,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,185662,DB00215,10039906,165,10938,64,5212,0.176234644,1.228444255,0.913295386,1.669543794,0.319019841,DB0021510039906_,1.14250198,0.205748535,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,185664,DB00321,10039906,105,7342,31,2819,0.211131811,1.300438047,0.861644627,2.014088306,0.362671524,DB0032110039906_,1.014257748,0.262701167,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,185665,DB00334,10039906,51,2798,31,2781,0.034244822,1.635016217,1.022872182,2.651960991,0.09389018,DB0033410039906_,2.365629476,0.491652723,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,olanzapine,DB00334
,185666,DB00370,10039906,53,4488,38,3625,0.597682987,1.126501416,0.726966651,1.760641118,0.742829322,DB0037010039906_,0.297288976,0.119116738,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,mirtazapine,DB00370
,185667,DB00425,10039906,130,12565,61,7423,0.152702338,1.259020071,0.92054334,1.738375189,0.287726234,DB0042510039906_,1.245745829,0.230333697,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,zolpidem,DB00425
,185668,DB00472,10039906,146,10613,89,4223,0.002173649,0.652768429,0.496818846,0.861651033,0.010421224,DB0047210039906_,4.56391079,-0.42653284,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,185670,DB00490,10039906,53,4017,39,1537,0.003121067,0.520017187,0.335960701,0.811241471,0.013975683,DB0049010039906_,4.270436418,-0.653893416,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,buspirone,DB00490
,185671,DB00540,10039906,33,2450,18,1073,0.447281281,0.803003032,0.436932251,1.521838139,0.615055635,DB0054010039906_,0.486042552,-0.219396789,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,nortriptyline,DB00540
,185672,DB00715,10039906,56,4787,38,2249,0.094647226,0.692381455,0.449023755,1.077955579,0.202713573,DB0071510039906_,1.595961265,-0.36761824,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,paroxetine,DB00715
,185674,DB00996,10039906,405,38548,208,22217,0.191281696,1.122229014,0.946290178,1.334005176,0.338191857,DB0099610039906_,1.08414192,0.115316899,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,185675,DB01075,10039906,217,19731,107,10990,0.322131495,1.129613331,0.890954512,1.439283253,0.490484061,DB0107510039906_,0.712362496,0.121875389,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,185676,DB01104,10039906,173,15290,94,7192,0.262640532,0.865700746,0.668463714,1.126866994,0.42440841,DB0110410039906_,0.857059056,-0.14421599,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,185677,DB01175,10039906,117,10607,70,4822,0.080651488,0.75982931,0.559145872,1.039032878,0.179449305,DB0117510039906_,1.717862536,-0.274661463,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,185678,DB01224,10039906,128,7980,106,5811,0.350215871,0.879340369,0.672858857,1.151130756,0.519830825,DB0122410039906_,0.654251857,-0.128583233,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,185680,DB00334,10040108,25,2824,48,2764,0.00645411,0.509829653,0.300344462,0.846115745,0.025093748,DB0033410040108_,3.685136531,-0.673678624,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,olanzapine,DB00334
,185690,DB00678,10001949,51,15548,33,10691,0.82471092,1.062680907,0.672163575,1.701099314,0.907142323,DB0067810001949_,0.097455925,0.060794872,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,losartan,DB00678
,185694,DB01068,10029331,96,13667,50,6790,0.791706849,0.953891557,0.669964421,1.372710028,0.887231487,DB0106810029331_,0.119649354,-0.047205286,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,185698,DB01109,10013710,32,4380,58,4212,0.004035204,0.530603807,0.332687481,0.832685291,0.017203037,DB0110910013710_,4.062669315,-0.633739663,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,185716,DB00656,10006002,35,11978,19,6600,1,1.015018262,0.56443592,1.879968124,1,DB0065610006002_,0,0.014906604,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,185718,DB01098,10006002,36,8113,20,7189,0.107271596,1.594943165,0.89796651,2.910690982,0.22206213,DB0109810006002_,1.504798072,0.466838102,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,185756,DB00410,10012378,38,1567,13,996,0.058766216,1.857529005,0.962116741,3.819988714,0.141188246,DB0041010012378_,1.957661204,0.619247113,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,mupirocin,DB00410
,185770,DB00999,10024570,61,21369,46,12193,0.159378785,0.756681405,0.507260855,1.13554178,0.296648587,DB0099910024570_,1.215207048,-0.278812979,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,185773,DB00443,10037844,93,2053,35,1155,0.048073804,1.494715655,0.99584123,2.288255195,0.121480693,DB0044310037844_,2.107999935,0.401935992,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,betamethasone,DB00443
,185785,DB01018,10022437,13,399,43,736,0.083333822,0.557921685,0.271895223,1.072326378,0.184015584,DB0101810022437_,1.692734828,-0.583536677,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,guanfacine,DB01018
,185790,DB00422,10076309,44,3391,70,2879,0.001191596,0.533723646,0.356240346,0.792067976,0.0063715,DB0042210076309_,5.055920436,-0.627877092,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,methylphenidate,DB00422
,185815,DB00158,10010144,31,16784,46,8058,1.06336768815249e-06,0.323561797,0.19817633,0.521778098,1.51084430719396e-05,DB0015810010144_,11.10025683,-1.128365156,male,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,folic acid,DB00158
,185816,DB00227,10010144,18,2449,47,1756,1.39837507157699e-06,0.274687919,0.149600175,0.483897299,1.93606998980254e-05,DB0022710010144_,10.85226533,-1.292119666,male,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,lovastatin,DB00227
,185817,DB00678,10010144,174,15425,205,10519,1.58210179117068e-07,0.578850386,0.469435658,0.713025087,2.75218700072278e-06,DB0067810010144_,12.80311469,-0.546711236,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,losartan,DB00678
,185818,DB01592,10010144,62,6214,22,3045,0.242743772,1.380943703,0.83512793,2.363950114,0.400987936,DB0159210010144_,0.913823936,0.322767108,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,iron,DB01592
,185821,DB06605,10043554,68,14005,93,12940,0.014172346,0.675595155,0.486280145,0.934550963,0.047059134,DB0660510043554_,3.056350303,-0.392161266,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,apixaban,DB06605
,185854,DB00571,10044565,71,5052,45,2564,0.276280241,0.800798634,0.541788203,1.194384143,0.439723047,DB0057110044565_,0.821610189,-0.222145757,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,propranolol,DB00571
,185856,DB01276,10054107,46,1971,24,1487,0.179222259,1.445860697,0.859964087,2.48848007,0.322904729,DB0127610054107_,1.130397956,0.368704782,NA,10054107,Nodule,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,185857,DB01276,10064355,32,1985,24,1487,1,0.998824829,0.567394671,1.78018697,1,DB0127610064355_,0,-0.001175862,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,exenatide,DB01276
,185868,DB06605,10061225,38,14035,29,13004,0.464136279,1.214077918,0.728727665,2.04226937,0.631313568,DB0660510061225_,0.459952602,0.193984874,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,185873,DB00186,10005470,14,16887,38,9970,1.68766812231699e-07,0.217527813,0.108805113,0.410953323,2.91940484337625e-06,DB0018610005470_,12.74413078,-1.525428559,male,10005470,Blood creatine phosphokinase increased,10022891,Investigations,Inv,lorazepam,DB00186
,185881,DB00814,10000087,118,8169,34,3381,0.072042509,1.436422928,0.97124513,2.174982907,0.164864822,DB0081410000087_,1.802629404,0.362155946,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,185900,DB05676,10060933,103,47026,55,25274,1,1.006492311,0.718401097,1.423424058,1,DB0567610060933_,0,0.006471327,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,185901,DB00268,10061428,51,2924,28,1517,0.811626082,0.944987636,0.582022461,1.563168676,0.898803639,DB0026810061428_,0.10669069,-0.056583435,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ropinirole,DB00268
,185908,DB00497,10060795,51,19216,35,16340,0.386294225,1.239048193,0.789825765,1.96410379,0.55644715,DB0049710060795_,0.586183082,0.214343498,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,oxycodone,DB00497
,185911,DB06605,10053762,372,13701,306,12727,0.128957237,1.129257969,0.966191091,1.320585982,0.254086501,DB0660510053762_,1.370080515,0.121560753,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,185969,DB00572,10061818,71,2831,69,2057,0.099104351,0.747712402,0.526460276,1.062392857,0.209494379,DB0057210061818_,1.563058371,-0.290736864,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,atropine,DB00572
,185985,DB01062,10022086,44,4442,6,1739,0.010619393,2.870334203,1.215761959,8.25781386,0.037339409,DB0106210022086_,3.287705968,1.05442847,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,186006,DB00091,10038695,26,5484,45,2625,1.31867948077152e-07,0.276620809,0.163446162,0.459236177,2.3372548989939e-06,DB0009110038695_,12.96653344,-1.28510763,male,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclosporine,DB00091
,186009,DB01222,10038695,97,9177,116,5289,1.91008279041757e-07,0.481948853,0.363378015,0.638077047,3.25804841960583e-06,DB0122210038695_,12.63438219,-0.729917285,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,budesonide,DB01222
,186026,DB00437,10042682,44,6877,33,11513,0.000540047,2.232100636,1.38770368,3.622001482,0.003288958,DB0043710042682_,5.717184358,0.802943131,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,186028,DB00736,10042682,41,10550,13,5540,0.116436166,1.656095247,0.869056086,3.371467679,0.235778638,DB0073610042682_,1.444861887,0.504462571,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,esomeprazole,DB00736
,186035,DB00374,10048961,49,17667,13,5711,0.656910228,1.218419148,0.650364166,2.449955053,0.790246469,DB0037410048961_,0.235410396,0.197554239,NA,10048961,Localised oedema,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,186036,DB06403,10048961,45,21426,10,6651,0.427259325,1.396844731,0.693522741,3.110142071,0.595877931,DB0640310048961_,0.517719446,0.33421593,NA,10048961,Localised oedema,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,186057,DB08932,10003997,46,19397,10,6587,0.221319075,1.562032161,0.777025779,3.473581378,0.375144894,DB0893210003997_,0.980442943,0.445987641,NA,10003997,Bacteraemia,10021881,Infections and infestations,Infec,macitentan,DB08932
,186061,DB00126,10013971,59,10112,27,5918,0.314703005,1.27886312,0.797187841,2.100353123,0.482288341,DB0012610013971_,0.729213125,0.245971496,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,186071,DB00983,10037660,45,3456,9,1731,0.008573369,2.503977683,1.20516888,5.839381172,0.031473602,DB0098310037660_,3.458606106,0.917880541,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,formoterol,DB00983
,186084,DB08932,10047571,162,19281,35,6562,0.013483898,1.575182762,1.08632923,2.342519151,0.045163972,DB0893210047571_,3.097455593,0.454371305,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,macitentan,DB08932
,186101,DB00843,10044565,34,2160,36,2137,0.810353642,0.934372556,0.564890951,1.542635866,0.897944669,DB0084310044565_,0.107646829,-0.067880038,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,donepezil,DB00843
,186132,DB00273,10002034,43,8438,9,2184,0.730455993,1.236602138,0.593411718,2.889528341,0.843179297,DB0027310002034_,0.170575654,0.212367407,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,topiramate,DB00273
,186133,DB00115,10003119,25,18400,32,10440,0.00227645,0.443282172,0.251701752,0.772489695,0.010813496,DB0011510003119_,4.52696032,-0.813548755,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,cyanocobalamin,DB00115
,186144,DB00273,10008469,45,8436,6,2187,0.162466265,1.944207397,0.825445264,5.583927163,0.300607193,DB0027310008469_,1.201950873,0.664854386,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,186147,DB00273,10011224,110,8371,16,2177,0.026454104,1.787827258,1.050553919,3.244375381,0.076766142,DB0027310011224_,2.566991593,0.58100106,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,topiramate,DB00273
,186149,DB00598,10013573,37,1551,20,1008,0.584231519,1.202211796,0.675493263,2.199524771,0.732054487,DB0059810013573_,0.311900332,0.184163024,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,labetalol,DB00598
,186151,DB00343,10013971,165,8571,50,5045,2.31822396241225e-05,1.94233529,1.40472856,2.727071193,0.000226607,DB0034310013971_,8.392295049,0.663891007,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,186153,DB00641,10017885,95,14029,63,12412,0.078879017,1.334112967,0.959208321,1.866479227,0.176454039,DB0064110017885_,1.734694836,0.288266627,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,186160,DB00115,10036790,77,18348,40,10432,0.700302711,1.094491938,0.737009969,1.647607534,0.819879108,DB0011510036790_,0.198598379,0.090290272,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,186163,DB00338,10040984,105,33569,72,22200,0.817897688,0.964409031,0.707422241,1.321111926,0.902764791,DB0033810040984_,0.102293235,-0.036239768,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,186165,DB00682,10040984,41,19418,18,16346,0.025339682,1.917363172,1.076719786,3.547238384,0.074245185,DB0068210040984_,2.600382358,0.650950894,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,186187,DB01285,10025482,67,1209,9,600,4.51337186401045e-05,3.692581345,1.817117719,8.483474312,0.000405171,DB0128510025482_,7.811202111,1.306325765,female,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,corticotropin,DB01285
,186198,DB00115,10034474,33,18392,17,10455,0.883084522,1.103477791,0.59690609,2.113342017,0.951117766,DB0011510034474_,0.050117391,0.09846682,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,cyanocobalamin,DB00115
,186199,DB00169,10034474,48,38643,35,18140,0.058629391,0.643781027,0.407671559,1.025870278,0.14093681,DB0016910034474_,1.959443647,-0.44039663,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,cholecalciferol,DB00169
,186214,DB00051,10027940,39,25692,15,11405,0.768049905,1.154161107,0.621779707,2.254721321,0.872719842,DB0005110027940_,0.136140688,0.143373766,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,adalimumab,DB00051
,186220,DB01109,10020919,46,4366,37,4233,0.44059348,1.205343336,0.763165186,1.915373014,0.608933387,DB0110910020919_,0.496046398,0.186764453,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,heparin,DB01109
,186221,DB01109,10038687,19,4393,33,4237,0.050479112,0.555352715,0.29785299,1.007534936,0.125895924,DB0110910038687_,2.072299716,-0.588151845,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,heparin,DB01109
,186225,DB00203,10060795,28,13850,31,8907,0.044341303,0.58090307,0.335459813,1.001640695,0.114288209,DB0020310060795_,2.169031875,-0.543171369,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,sildenafil,DB00203
,186227,DB06403,10060795,60,21411,18,6643,1,1.034217471,0.601829412,1.8626466,1,DB0640310060795_,0,0.033645075,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,ambrisentan,DB06403
,186240,DB00736,10039906,65,10526,44,5509,0.189704748,0.77319586,0.518558423,1.162430221,0.33613464,DB0073610039906_,1.090243486,-0.257222886,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,esomeprazole,DB00736
,186241,DB01068,10039906,332,13431,206,6634,0.012202996,0.796075313,0.665287538,0.954266141,0.041709004,DB0106810039906_,3.177038245,-0.228061483,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,186243,DB06724,10039906,53,7876,31,3888,0.485291158,0.844008868,0.530964806,1.362613218,0.649333749,DB0672410039906_,0.431808444,-0.169592277,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,186253,DB05259,10039906,124,11146,33,2695,0.612921616,0.908536809,0.613020538,1.380746389,0.754720666,DB0525910039906_,0.281407578,-0.095919876,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,186285,DB00153,10019974,43,7380,9,3430,0.024899427,2.220428867,1.066081943,5.186735014,0.073261481,DB0015310019974_,2.6137203,0.79770036,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,ergocalciferol,DB00153
,186286,DB00758,10019974,37,8263,23,10051,0.012969555,1.956698583,1.131291715,3.451893711,0.043795576,DB0075810019974_,3.128222467,0.671258657,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,clopidogrel,DB00758
,186301,DB00331,10069339,548,24398,731,20021,1.53833259524303e-17,0.61518496,0.548819927,0.689277133,1.26359600831134e-15,DB0033110069339_,34.30481476,-0.485832308,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,186302,DB00695,10069339,744,27305,783,19745,5.92030097415988e-13,0.687127871,0.619617855,0.761911633,2.7276969518982e-11,DB0069510069339_,24.32497838,-0.375234874,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,186303,DB00722,10069339,548,24855,910,25122,4.27526751845587e-20,0.608676529,0.545648292,0.678448838,4.46820702674404e-18,DB0072210069339_,39.94954446,-0.496468304,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,186304,DB00811,10069339,34,2764,68,4088,0.156129928,0.739539422,0.473576179,1.135659803,0.2922988,DB0081110069339_,1.229978712,-0.301727689,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ribavirin,DB00811
,186305,DB00999,10069339,364,21066,397,11842,3.21809998189735e-19,0.515407504,0.445016911,0.596791685,3.12131948428679e-17,DB0099910069339_,38.00569076,-0.662797421,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,hydrochlorothiazide,DB00999
,186313,DB00051,10007697,58,25673,15,11405,0.074448745,1.71770959,0.96035101,3.26497546,0.168922721,DB0005110007697_,1.778313943,0.540991769,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,186322,DB00563,10047943,56,46590,25,15323,0.199499256,0.736718401,0.451986932,1.232638809,0.348462501,DB0056310047943_,1.054224656,-0.305549547,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,methotrexate,DB00563
,186324,DB00051,10060820,33,25698,23,11397,0.110073314,0.636330989,0.362336561,1.135515297,0.226169791,DB0005110060820_,1.486469276,-0.452036428,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,186353,DB00480,10061224,124,67304,122,67540,0.898541212,1.019960251,0.787737588,1.320835554,0.956423691,DB0048010061224_,0.044554273,0.019763657,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,186355,DB01234,10061224,75,31550,48,32840,0.008684443,1.626362926,1.116823825,2.38851366,0.0318125,DB0123410061224_,3.447895997,0.486346188,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,186358,DB00425,10030124,137,12558,66,7418,0.188871111,1.226095841,0.906258097,1.673105615,0.335131951,DB0042510030124_,1.093230942,0.203835008,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,186361,DB00051,10051055,46,25685,38,11382,0.006072462,0.536411797,0.341275994,0.847698188,0.023892624,DB0005110051055_,3.734185479,-0.622853134,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,adalimumab,DB00051
,186367,DB01104,10013786,75,15388,17,7269,0.004861242,2.083976058,1.217885394,3.767872119,0.020005912,DB0110410013786_,3.91172746,0.734277635,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,sertraline,DB01104
,186369,DB00273,10039906,290,8191,184,2009,1.07599882002568e-20,0.38661072,0.318168774,0.470677021,1.20865935830662e-18,DB0027310039906_,41.2570199,-0.950336983,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,186370,DB00448,10039906,36,5109,30,3094,0.204059932,0.726765535,0.434245551,1.224317472,0.353900457,DB0044810039906_,1.038739601,-0.319151364,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,lansoprazole,DB00448
,186371,DB01222,10039906,44,9230,38,5367,0.084610029,0.673330679,0.425641317,1.069455551,0.186083305,DB0122210039906_,1.681560829,-0.395518719,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,186372,DB00762,10013887,45,1118,21,1348,0.000250766,2.582760081,1.496515945,4.593127045,0.001740303,DB0076210013887_,6.353696164,0.948858626,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,irinotecan,DB00762
,186388,DB00635,10016970,62,32991,16,23778,0.000118431,2.79278075,1.591535472,5.187173368,0.00092127,DB0063510016970_,6.98975789,1.027037784,female,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,186394,DB08895,10061159,94,28020,10,6636,0.011980799,2.226134766,1.157718265,4.796637288,0.041100928,DB0889510061159_,3.191724571,0.800266793,NA,10061159,Foot deformity,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,186402,DB00313,10039906,77,1162,92,1425,0.873541407,1.026387185,0.740568511,1.419355851,0.944995818,DB0031310039906_,0.056574777,0.026045049,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,valproic acid,DB00313
,186432,DB00635,10006811,54,32999,14,23780,0.000300094,2.779470551,1.522154848,5.41905723,0.002018674,DB0063510006811_,6.205314284,1.02226046,female,10006811,Bursitis,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,186447,DB09130,10053762,129,6741,6,115,0.029270759,0.366873237,0.159254774,1.039268935,0.083090887,DB0913010053762_,2.48782025,-1.002738895,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,copper,DB09130
,186467,DB00476,10033664,124,17133,16,6161,1.88286601856939e-05,2.786984311,1.648091107,5.030732431,0.00018944,DB0047610033664_,8.571439554,1.024960119,female,10033664,Panic attack,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,186468,DB00471,10062355,116,14073,42,5423,0.78939783,1.064290274,0.740651626,1.555368428,0.885855574,DB0047110062355_,0.12120135,0.062308168,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,186470,DB13867,10062355,36,4514,14,2540,0.300521885,1.446855882,0.759823572,2.909739882,0.466733543,DB1386710062355_,0.761996756,0.369392845,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,186477,DB00051,10012601,82,25649,23,11397,0.056068895,1.584167963,0.986891567,2.638376979,0.136201737,DB0005110012601_,1.993618128,0.460059325,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,adalimumab,DB00051
,186482,DB00734,10001488,53,3997,91,4811,0.042783092,0.701057135,0.488602385,0.997144944,0.111278746,DB0073410001488_,2.195716997,-0.35516589,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,186486,DB00476,10019063,129,17128,66,6111,0.021955097,0.697362722,0.513654136,0.954415165,0.066538653,DB0047610019063_,2.709972253,-0.360449599,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,186498,DB00571,10001497,38,5085,28,2581,0.150257605,0.688859191,0.410765463,1.168291224,0.284342776,DB0057110001497_,1.25757481,-0.372718395,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,propranolol,DB00571
,186500,DB00571,10020772,71,5052,21,2588,0.026362617,1.731857005,1.048986501,2.975005905,0.076551191,DB0057110020772_,2.569795593,0.549194246,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,propranolol,DB00571
,186502,DB00571,10043071,34,5089,17,2592,1,1.018665659,0.552310367,1.948231579,1,DB0057110043071_,0,0.018493594,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,propranolol,DB00571
,186510,DB00480,10061284,40,67388,34,67628,0.487856879,1.180657764,0.728574148,1.92318109,0.651528496,DB0048010061284_,0.428434145,0.16607171,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,186523,DB06643,10061520,72,52349,11,7504,0.867748261,0.938246615,0.494098744,1.963819348,0.940780921,DB0664310061520_,0.061044982,-0.063742449,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,186525,DB01012,10037844,46,10586,37,8648,1,1.015640514,0.643875869,1.611990407,1,DB0101210037844_,0,0.015519461,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cinacalcet,DB01012
,186532,DB00404,10069339,189,19703,129,9733,0.00578464,0.723729544,0.574736416,0.913769883,0.022995084,DB0040410069339_,3.772474809,-0.323337514,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,alprazolam,DB00404
,186533,DB00813,10069339,154,10418,216,9952,0.000287622,0.681088836,0.549214318,0.842988614,0.001949372,DB0081310069339_,6.240247898,-0.384062532,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,fentanyl,DB00813
,186536,DB00722,10029883,36,25367,29,26003,0.38522673,1.272493721,0.75839282,2.152229586,0.555367137,DB0072210029883_,0.588125876,0.240978535,NA,10029883,Obesity,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,186555,DB00051,10019303,54,25677,25,11395,0.902917429,0.958571447,0.585992122,1.608383903,0.957326661,DB0005110019303_,0.043610607,-0.042311179,NA,10019303,Heart rate increased,10022891,Investigations,Inv,adalimumab,DB00051
,186568,DB06724,10028836,61,7868,8,3911,5.3024850537968e-05,3.789681732,1.804593903,9.180498902,0.000464509,DB0672410028836_,7.674530383,1.33228204,female,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,186578,DB00669,10000087,50,6327,9,1088,0.853840921,0.955339338,0.463384679,2.216258711,0.9288062,DB0066910000087_,0.073855173,-0.045688674,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,sumatriptan,DB00669
,186579,DB00795,10012378,58,4511,24,1479,0.366807483,0.792370375,0.482674043,1.3385468,0.536445484,DB0079510012378_,0.622790336,-0.232726351,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,sulfasalazine,DB00795
,186580,DB00795,10019211,179,4390,56,1447,0.817114834,1.053557043,0.771417804,1.457702154,0.902146946,DB0079510019211_,0.102977861,0.052172099,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sulfasalazine,DB00795
,186583,DB00795,10047895,50,4519,28,1475,0.024948386,0.582915332,0.358457417,0.965387218,0.073364471,DB0079510047895_,2.612315511,-0.539713331,NA,10047895,Weight decreased,10022891,Investigations,Inv,sulfasalazine,DB00795
,186584,DB00016,10002855,31,2731,21,2269,0.487957115,1.226415166,0.680398199,2.252290276,0.65159291,DB0001610002855_,0.428335283,0.204095415,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,erythropoietin,DB00016
,186594,DB01267,10012239,31,2821,72,3643,0.006580716,0.556064314,0.351625791,0.861062997,0.025493607,DB0126710012239_,3.669327577,-0.586871318,NA,10012239,Delusion,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,186600,DB01267,10019063,34,2818,52,3663,0.511830448,0.849931313,0.533284423,1.338828953,0.672152248,DB0126710019063_,0.397270404,-0.162599741,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,186603,DB01267,10039906,19,2833,33,3682,0.32957029,0.748334961,0.401144528,1.358488144,0.498231728,DB0126710039906_,0.696689992,-0.289904593,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,paliperidone,DB01267
,186604,DB01267,10042458,30,2822,65,3650,0.021426044,0.597003718,0.372768293,0.936596344,0.065296048,DB0126710042458_,2.728823763,-0.515831937,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,186654,DB00541,10020919,21,3113,35,4262,0.500545932,0.821480087,0.45343135,1.454284196,0.662098371,DB0054110020919_,0.412341138,-0.196647581,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,vincristine,DB00541
,186655,DB00563,10020919,32,46614,34,15314,4.42790920347196e-06,0.309210263,0.184653406,0.516643515,5.31450198234066e-05,DB0056310020919_,9.842486158,-1.173733772,male,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,186680,DB05676,10011224,519,46610,230,25099,0.0151872,1.215075144,1.037582182,1.42654449,0.049802951,DB0567610011224_,2.999681031,0.194805922,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,186688,DB01067,10047942,54,4307,42,4781,0.099796211,1.42714594,0.933800202,2.194327034,0.210482922,DB0106710047942_,1.558350759,0.355676604,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,glipizide,DB01067
,186692,DB00997,10076309,125,5206,76,3438,0.610108276,1.086176697,0.807451501,1.469130002,0.752296103,DB0099710076309_,0.284625278,0.082663912,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,doxorubicin,DB00997
,186707,DB14512,10063829,71,4773,32,2380,0.674763667,1.106334086,0.7168932,1.741149633,0.802790166,DB1451210063829_,0.219661912,0.101051925,NA,10063829,Device malfunction,10077536,Product issues,Prod,mometasone furoate,DB14512
,186736,DB01050,10013654,75,18033,70,9301,0.000418852,0.552605218,0.393233594,0.777456381,0.002660267,DB0105010013654_,5.929328706,-0.593111424,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,186739,DB01050,10069339,321,17787,318,9053,1.99644604051754e-16,0.513765507,0.437638834,0.603142526,1.43671898652001e-14,DB0105010069339_,31.87382927,-0.66598833,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ibuprofen,DB01050
,186746,DB05679,10028411,45,6886,26,4883,0.468953807,1.227299975,0.739896991,2.07524356,0.635342473,DB0567910028411_,0.453591098,0.204816614,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ustekinumab,DB05679
,186748,DB05259,10028411,78,11192,22,2706,0.52650304,0.857199832,0.527244147,1.448196925,0.684304436,DB0525910028411_,0.379352379,-0.154084212,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,glatiramer,DB05259
,186783,DB00091,10001760,70,5440,10,2660,5.67712950353626e-05,3.42237623,1.751294542,7.458700042,0.000492161,DB0009110001760_,7.616703763,1.230335114,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,cyclosporine,DB00091
,186790,DB11089,10001760,125,10050,19,8388,1.97097129298031e-16,5.49052801,3.36929168,9.434479471,1.42326869329636e-14,DB1108910001760_,31.88323518,1.703024428,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,docusate,DB11089
,186813,DB08910,10041349,102,16642,100,17388,0.672293946,1.065753207,0.80012883,1.419755763,0.801035624,DB0891010041349_,0.221849859,0.063681786,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,186831,DB01076,10017626,23,25724,33,25550,0.183333265,0.692263601,0.388005828,1.215491427,0.328040495,DB0107610017626_,1.114618217,-0.36778847,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,atorvastatin,DB01076
,186834,DB00065,10019303,36,9428,15,4942,0.555074736,1.258068588,0.671009725,2.475631491,0.708551559,DB0006510019303_,0.34453245,0.229577678,NA,10019303,Heart rate increased,10022891,Investigations,Inv,infliximab,DB00065
,186837,DB00177,10029331,45,4755,36,2814,0.203560089,0.739796749,0.465412738,1.183494984,0.353371657,DB0017710029331_,1.040234922,-0.301379794,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,valsartan,DB00177
,186934,DB05676,10038428,48,47081,30,25299,0.552836796,0.85976965,0.533639553,1.405721985,0.706536098,DB0567610038428_,0.347380985,-0.151090775,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,apremilast,DB05676
,186935,DB08868,10011224,190,9012,52,2459,1,0.996982889,0.727495881,1.386995037,1,DB0886810011224_,0,-0.003021672,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fingolimod,DB08868
,186945,DB00563,10033295,34,46612,21,15327,0.027708675,0.532405449,0.300123348,0.965602897,0.079589392,DB0056310033295_,2.530874456,-0.630349957,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,186972,DB00635,10071404,61,32992,72,23722,0.004737543,0.609191399,0.42573514,0.869284932,0.019581151,DB0063510071404_,3.933187876,-0.495622776,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,186974,DB00993,10071404,21,3228,33,1586,2.98196357373268e-05,0.312743717,0.17136413,0.558977516,0.000282352,DB0099310071404_,8.172356072,-1.16237122,male,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,azathioprine,DB00993
,186981,DB06262,10013709,350,3450,434,3880,0.200618907,0.906989925,0.779708125,1.054478324,0.349747871,DB0626210013709_,1.050542752,-0.097623937,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,186982,DB00190,10024855,45,3252,68,4606,0.773509319,0.937293624,0.626659551,1.390183379,0.876309396,DB0019010024855_,0.132036058,-0.06475868,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,186983,DB00211,10024855,43,1393,58,1573,0.417947294,0.837227399,0.547047053,1.272780033,0.586986435,DB0021110024855_,0.532753569,-0.177659562,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,midodrine,DB00211
,186984,DB06262,10024855,195,3605,194,4120,0.193028691,1.148726869,0.931938359,1.415952968,0.340434352,DB0626210024855_,1.077532971,0.138654259,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,186996,DB00956,10013663,27,5787,38,3429,0.00069245,0.421049435,0.246743278,0.709390188,0.004054137,DB0095610013663_,5.50801748,-0.865005029,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,hydrocodone,DB00956
,187008,DB00186,10061284,52,16849,22,9986,0.228106312,1.400853889,0.83542088,2.423724962,0.383508661,DB0018610061284_,0.958393075,0.337081971,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,187010,DB14512,10046306,59,4785,20,2392,0.149883712,1.474618172,0.872619804,2.592023564,0.283768024,DB1451210046306_,1.25959819,0.38839909,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,mometasone furoate,DB14512
,187020,DB00571,10042458,46,5077,21,2588,0.795382575,1.116573635,0.651383215,1.974283481,0.889265461,DB0057110042458_,0.117359482,0.110264742,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,propranolol,DB00571
,187021,DB01255,10042458,38,2095,32,1546,0.626116964,0.876345956,0.530445626,1.456108961,0.765678069,DB0125510042458_,0.266993473,-0.131994339,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,lisdexamfetamine,DB01255
,187030,DB00264,10039674,50,29557,33,24859,0.321192044,1.2743155,0.804622322,2.042435946,0.489478947,DB0026410039674_,0.714413828,0.242409172,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,187040,DB00482,10069339,59,8200,71,3000,2.86451712164854e-11,0.304074104,0.210966,0.436777829,1.01955088073842e-09,DB0048210069339_,20.70390362,-1.190483843,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,celecoxib,DB00482
,187062,DB01590,10018884,53,4685,52,2815,0.014620775,0.612475671,0.408527867,0.918544509,0.048310127,DB0159010018884_,3.030114076,-0.490246058,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,everolimus,DB01590
,187093,DB01220,10013709,46,1248,31,1105,0.296214387,1.313695755,0.808883829,2.159472896,0.462063154,DB0122010013709_,0.772053701,0.272844352,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,rifaximin,DB01220
,187108,DB01050,10045555,51,18057,31,9340,0.48530194,0.850975357,0.533797427,1.376839976,0.649333749,DB0105010045555_,0.431808444,-0.161372109,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,187126,DB00193,10037884,64,19256,27,8675,0.821354118,1.067869768,0.670700159,1.743350694,0.904794141,DB0019310037884_,0.10004783,0.065665793,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,187142,DB00635,10051358,101,32952,123,23671,0.000100916,0.589882282,0.448564707,0.774197593,0.000804181,DB0063510051358_,7.125686617,-0.527832284,NA,10051358,Post transplant lymphoproliferative disorder,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,187171,DB00321,10069339,110,7337,60,2790,0.03035587,0.697177767,0.502847553,0.974559986,0.085451572,DB0032110069339_,2.459805478,-0.360714855,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,amitriptyline,DB00321
,187172,DB00425,10069339,139,12556,123,7361,0.001243457,0.662555005,0.515112431,0.852983776,0.006583598,DB0042510069339_,5.023173842,-0.411651699,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,zolpidem,DB00425
,187174,DB01373,10069339,148,22572,76,7305,0.001733713,0.630239949,0.474148655,0.843532085,0.008641442,DB0137310069339_,4.751185869,-0.46165466,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,calcium,DB01373
,187196,DB00958,10070863,37,4557,30,2555,0.158968942,0.691565633,0.414588871,1.162072077,0.296126902,DB0095810070863_,1.216967194,-0.368797219,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,carboplatin,DB00958
,187200,DB01020,10019211,54,1759,41,1837,0.1453987,1.375351346,0.89438768,2.129005373,0.277616302,DB0102010019211_,1.281515328,0.318709223,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,isosorbide mononitrate,DB01020
,187204,DB09270,10003549,129,2985,115,2253,0.20954643,0.846688331,0.649305641,1.105109634,0.360664589,DB0927010003549_,1.01980687,-0.16642262,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,187208,DB00924,10028735,45,10117,12,4239,0.19064208,1.571222184,0.816422738,3.266320457,0.337374744,DB0092410028735_,1.086560965,0.451853777,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,187220,DB00073,10013700,181,7225,36,6371,1.56840646106114e-20,4.432968982,3.080820058,6.539997208,1.72853517102692e-18,DB0007310013700_,40.89925735,1.489069559,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,rituximab,DB00073
,187225,DB00341,10029366,40,11365,18,5050,1,0.987437647,0.552586214,1.831747052,1,DB0034110029366_,0,-0.012641926,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,cetirizine,DB00341
,187228,DB11089,10029366,75,10100,43,8364,0.063121916,1.44436247,0.978698678,2.155607399,0.14918358,DB1108910029366_,1.902577648,0.367668027,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,docusate,DB11089
,187241,DB01373,10029354,197,22523,67,7314,0.720057838,0.954815029,0.7192223,1.281075205,0.83476912,DB0137310029354_,0.180600095,-0.046237644,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,calcium,DB01373
,187261,DB08910,10056812,30,16714,31,17457,1,1.010762362,0.590816472,1.727128657,1,DB0891010056812_,0,0.01070486,NA,10056812,Body height decreased,10022891,Investigations,Inv,pomalidomide,DB08910
,187266,DB01234,10014011,63,31562,37,32851,0.006586152,1.772212975,1.162297343,2.736990607,0.025509027,DB0123410014011_,3.668722875,0.572229034,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,187275,DB08908,10039906,247,10426,93,3186,0.092406091,0.811604753,0.634676635,1.045129969,0.199057049,DB0890810039906_,1.614163819,-0.208741815,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,187276,DB06589,10051398,79,1951,143,2510,0.018188988,0.710786395,0.529561152,0.948454228,0.057330644,DB0658910051398_,2.858919991,-0.341383324,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pazopanib,DB06589
,187300,DB00169,10053425,220,38471,27,18148,1.42232771436472e-14,3.843285703,2.569455671,5.967367057,8.18967885478131e-13,DB0016910053425_,27.83073152,1.346327652,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,187307,DB00331,10012374,72,24874,31,20721,0.001989943,1.934744436,1.252896231,3.051825854,0.009684437,DB0033110012374_,4.637235162,0.659975243,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,metformin,DB00331
,187346,DB00028,10005191,40,13418,27,5588,0.059558918,0.616988222,0.368950534,1.046602657,0.142649429,DB0002810005191_,1.947365204,-0.482905344,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,human immunoglobulin g,DB00028
,187347,DB00028,10016334,47,13411,12,5603,0.152010763,1.636324224,0.853857173,3.39111163,0.286772619,DB0002810016334_,1.249065646,0.492452399,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,187399,DB00364,10021789,42,2708,10,1390,0.026539279,2.15549096,1.060212245,4.833168145,0.076945174,DB0036410021789_,2.564662131,0.768018521,NA,10021789,Infection,10021881,Infections and infestations,Infec,sucralfate,DB00364
,187406,DB00047,10037884,32,9253,21,8497,0.270943551,1.39927929,0.781650633,2.555416165,0.433653527,DB0004710037884_,0.835509389,0.335957311,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,insulin glargine,DB00047
,187414,DB06228,10013560,53,15859,73,16003,0.090022168,0.732629491,0.504073657,1.058684872,0.195217612,DB0622810013560_,1.633640384,-0.311115175,NA,10013560,Diverticulum intestinal haemorrhagic,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,187431,DB01281,10000087,51,8881,7,1791,0.479083966,1.469233762,0.662441025,3.844161143,0.644244342,DB0128110000087_,0.439677212,0.384741015,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,abatacept,DB01281
,187434,DB00563,10005728,43,46603,15,15333,0.879040469,0.943166827,0.513514819,1.828178813,0.949141622,DB0056310005728_,0.052197259,-0.058512101,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,methotrexate,DB00563
,187443,DB00051,10015916,47,25684,17,11403,0.501539892,1.227428647,0.691506955,2.281080482,0.663027515,DB0005110015916_,0.41093879,0.20492145,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,adalimumab,DB00051
,187445,DB00316,10015916,83,65391,37,36916,0.254250905,1.266434086,0.849662684,1.920031565,0.414873171,DB0031610015916_,0.879782417,0.236205145,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,acetaminophen,DB00316
,187449,DB01281,10019211,303,8629,44,1754,0.040506541,1.399732918,1.012990189,1.975085389,0.106658095,DB0128110019211_,2.238126931,0.336281446,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,abatacept,DB01281
,187456,DB00571,10028372,44,5079,18,2591,0.500955951,1.246933301,0.704263922,2.297584031,0.662438797,DB0057110028372_,0.411827108,0.220687178,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,propranolol,DB00571
,187458,DB01281,10028411,53,8879,11,1787,0.867494713,0.969713507,0.499338947,2.063060211,0.940554821,DB0128110028411_,0.061285343,-0.030754605,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,abatacept,DB01281
,187460,DB00186,10047461,39,16862,24,9984,0.896596832,0.962193684,0.5638658,1.673642746,0.956301489,DB0018610047461_,0.044682051,-0.038539514,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,lorazepam,DB00186
,187463,DB00051,10048439,111,25620,9,11411,9.43444716321722e-10,5.493308152,2.789923499,12.33248893,2.63532883831206e-08,DB0005110048439_,17.45167277,1.703530652,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,187466,DB00959,10049848,58,8020,15,4987,0.001545564,2.404224635,1.343069163,4.572786491,0.007882259,DB0095910049848_,4.843140752,0.877227454,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,187468,DB00316,10053156,93,65381,26,36927,0.001079344,2.020221069,1.295747642,3.252786674,0.005868218,DB0031610053156_,5.138204328,0.703206946,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,187471,DB00059,10005364,22,805,43,1064,0.160891642,0.676371743,0.382032811,1.166685047,0.298702981,DB0005910005364_,1.208305574,-0.391012439,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,pegaspargase,DB00059
,187472,DB00541,10005364,30,3104,51,4246,0.367449999,0.804677814,0.493572756,1.291097268,0.537116184,DB0054110005364_,0.62154085,-0.217313313,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,vincristine,DB00541
,187473,DB00563,10005364,52,46594,62,15286,1.85182498999892e-11,0.275164637,0.186528934,0.404523478,6.75575570605435e-10,DB0056310005364_,21.11545609,-1.29038568,male,10005364,Blood bilirubin increased,10022891,Investigations,Inv,methotrexate,DB00563
,187501,DB00688,10013573,105,6385,49,5329,0.000783898,1.788366598,1.259764764,2.569553227,0.004498856,DB0068810013573_,5.403932121,0.581302688,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,mycophenolate mofetil,DB00688
,187502,DB00715,10018884,34,4809,16,2271,1,1.003508967,0.537701991,1.951252965,1,DB0071510018884_,0,0.003502825,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,paroxetine,DB00715
,187528,DB00635,10039117,67,32986,32,23762,0.065916922,1.508254609,0.975502744,2.376357137,0.154011227,DB0063510039117_,1.870729777,0.410953094,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,187535,DB00196,10042772,61,5022,18,3267,0.002435456,2.204405567,1.282759234,3.970842805,0.011425301,DB0019610042772_,4.471925015,0.790457888,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,fluconazole,DB00196
,187557,DB00635,10015108,57,32996,47,23747,0.488194531,0.872823783,0.58256119,1.313265678,0.651793943,DB0063510015108_,0.428026805,-0.136021596,NA,10015108,Epstein-Barr virus infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,187560,DB05676,10003658,53,47076,41,25288,0.08357286,0.694370292,0.453100316,1.071009646,0.184411738,DB0567610003658_,1.690584314,-0.364749899,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,apremilast,DB05676
,187564,DB01174,10039906,100,839,125,667,0.001987651,0.636175141,0.474510003,0.851241252,0.009676866,DB0117410039906_,4.638017187,-0.452281375,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,phenobarbital,DB01174
,187572,DB01076,10002368,18,25729,34,25549,0.026488497,0.525717627,0.279445012,0.957628645,0.076831842,DB0107610002368_,2.56613611,-0.642991041,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,187585,DB00687,10005750,46,940,79,1006,0.012678543,0.623304691,0.418865483,0.918527552,0.043008459,DB0068710005750_,3.146358454,-0.472719809,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,fludrocortisone,DB00687
,187586,DB06262,10005750,309,3491,363,3951,0.657190651,0.963401456,0.819442853,1.132157393,0.790475278,DB0626210005750_,0.235120896,-0.037285074,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,droxidopa,DB06262
,187587,DB06262,10013573,627,3173,618,3696,0.007231844,1.181763968,1.045328988,1.336035868,0.027467525,DB0626210013573_,3.594750869,0.16700821,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,187588,DB06262,10019211,413,3387,229,4085,1.80998949523795e-20,2.174971162,1.833933368,2.584190165,1.95784254659792e-18,DB0626210019211_,40.77468855,0.777015406,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,187590,DB00787,10069339,210,16790,287,16961,0.000957215,0.739168648,0.614865778,0.88743481,0.005313704,DB0078710069339_,5.237466165,-0.302229172,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,acyclovir,DB00787
,187591,DB00904,10069339,412,22657,402,14054,2.05223349544181e-10,0.635755362,0.551854717,0.732407078,6.38000679215706e-09,DB0090410069339_,18.87009667,-0.45294144,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ondansetron,DB00904
,187602,DB01068,10016334,46,13717,8,6832,0.003435064,2.863771427,1.33743443,7.029184001,0.015096247,DB0106810016334_,4.19330909,1.052139437,female,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,187615,DB01065,10039906,70,4261,55,2996,0.58279482,0.894896726,0.617606349,1.302308593,0.730939768,DB0106510039906_,0.313424219,-0.111046958,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,melatonin,DB01065
,187617,DB00924,10008190,52,10110,46,4205,0.000316982,0.470192262,0.309537261,0.716258475,0.002110484,DB0092410008190_,6.160838084,-0.7546136,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,187621,DB01067,10062237,27,4334,32,4791,0.896097679,0.932703459,0.536644123,1.609946755,0.956301489,DB0106710062237_,0.044682051,-0.069667964,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,glipizide,DB01067
,187663,DB00178,10069339,20,1417,33,1647,0.266222493,0.704512372,0.381252207,1.271206965,0.428360754,DB0017810069339_,0.847789555,-0.350249386,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ramipril,DB00178
,187664,DB00526,10069339,21,1577,87,1807,1.02436464909935e-08,0.276686323,0.162340181,0.452127615,2.29996684050415e-07,DB0052610069339_,15.28520095,-1.284870823,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,oxaliplatin,DB00526
,187665,DB00544,10069339,19,2416,97,2556,1.10480272295581e-12,0.207288095,0.119288203,0.342624575,4.94293439538613e-11,DB0054410069339_,23.73047686,-1.573645688,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,fluorouracil,DB00544
,187666,DB00650,10069339,40,2091,108,1906,1.34102943722746e-09,0.33768525,0.22758622,0.492447723,3.63250311057316e-08,DB0065010069339_,17.13075877,-1.085641031,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,leucovorin,DB00650
,187667,DB01020,10069339,60,1753,73,1805,0.377368592,0.846337813,0.587328868,1.215672269,0.54729273,DB0102010069339_,0.602771464,-0.166836693,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,isosorbide mononitrate,DB01020
,187672,DB09038,10017533,257,1991,99,2442,1.28392616530258e-23,3.183253711,2.494837414,4.086562995,1.79989329359884e-21,DB0903810017533_,47.76655957,1.157903853,female,10017533,Fungal infection,10021881,Infections and infestations,Infec,empagliflozin,DB09038
,187677,DB00563,10007554,41,46605,26,15322,0.010455864,0.518470314,0.309535611,0.883068477,0.036870458,DB0056310007554_,3.300344647,-0.656872506,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,methotrexate,DB00563
,187681,DB00059,10029354,78,749,111,996,0.699057123,0.934450233,0.679503268,1.280313808,0.819056632,DB0005910029354_,0.19960205,-0.067796909,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,pegaspargase,DB00059
,187697,DB00059,10069339,34,793,46,1061,1,0.98893004,0.609389502,1.591048415,1,DB0005910069339_,0,-0.011131688,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,pegaspargase,DB00059
,187698,DB00541,10069339,70,3064,161,4136,0.00018701,0.586942346,0.435084528,0.785055139,0.001362969,DB0054110069339_,6.598089896,-0.532828682,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,vincristine,DB00541
,187699,DB00563,10069339,210,46436,264,15084,5.04151363246952e-47,0.258406468,0.214332999,0.311229881,2.70441195570329e-44,DB0056310069339_,100.3188596,-1.353221475,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,methotrexate,DB00563
,187700,DB00694,10069339,41,593,37,734,0.197933478,1.371262438,0.845531101,2.23047025,0.34651047,DB0069410069339_,1.059842243,0.315731803,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,daunorubicin,DB00694
,187701,DB01234,10069339,343,31282,530,32358,6.28056458440145e-09,0.669437644,0.582165386,0.768978205,1.47859059651583e-07,DB0123410069339_,15.72700632,-0.401317256,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,dexamethasone,DB01234
,187708,DB00051,10028245,47,25684,25,11395,0.446282912,0.834105466,0.50278252,1.414933531,0.614099237,DB0005110028245_,0.487598741,-0.181395426,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,187710,DB08895,10013781,304,27810,31,6615,8.33412810403634e-07,2.332593132,1.60732959,3.496878314,1.22074425864918e-05,DB0889510013781_,11.31346474,0.846980581,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,187735,DB00868,10061818,38,2946,14,1632,0.243447184,1.503512766,0.793495177,3.013461076,0.401786422,DB0086810061818_,0.911834619,0.407804215,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,benzonatate,DB00868
,187740,DB01611,10046306,156,11757,12,2349,0.000500676,2.597236902,1.442160355,5.143074906,0.00309508,DB0161110046306_,5.777941504,0.95444815,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,hydroxychloroquine,DB01611
,187758,DB00005,10039906,159,127923,63,42356,0.243664949,0.83562171,0.620296537,1.137564955,0.402054813,DB0000510039906_,0.911166848,-0.179579269,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,187759,DB00158,10039906,126,16689,51,8053,0.3338619,1.192115579,0.853604242,1.686462316,0.502924469,DB0015810039906_,0.687315282,0.175729526,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,187760,DB00482,10039906,38,8221,24,3047,0.044823885,0.586871406,0.342393481,1.02457274,0.11524388,DB0048210039906_,2.160704697,-0.532949553,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,187761,DB00563,10039906,167,46479,80,15268,0.007649694,0.685732791,0.521896826,0.907345124,0.028738971,DB0056310039906_,3.549501208,-0.377267245,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,187762,DB00788,10039906,75,9281,26,5035,0.047425546,1.5648763,0.988410653,2.551137468,0.120256653,DB0078810039906_,2.118127046,0.447806779,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,187776,DB01281,10024774,38,8894,18,1780,0.003856983,0.422550681,0.234682069,0.788447044,0.016560429,DB0128110024774_,4.10073923,-0.861445884,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,abatacept,DB01281
,187781,DB01065,10046571,133,4198,53,2998,0.000278646,1.791970512,1.289195127,2.521822583,0.001901233,DB0106510046571_,6.265252465,0.583315859,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,melatonin,DB01065
,187798,DB00564,10039906,163,2441,125,1338,0.007405732,0.714857419,0.557228621,0.918734467,0.028009568,DB0056410039906_,3.575209105,-0.33567217,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,carbamazepine,DB00564
,187799,DB09153,10039906,56,7743,62,5637,0.024602912,0.657593304,0.449083777,0.961067082,0.072624801,DB0915310039906_,2.622448798,-0.419168617,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,187808,DB01611,10044565,54,11859,11,2350,0.868049194,0.972793064,0.501977996,2.066489565,0.941029553,DB0161110044565_,0.060780734,-0.027583897,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,hydroxychloroquine,DB01611
,187822,DB01263,10011906,47,577,83,782,0.192589531,0.767585684,0.516270489,1.130354839,0.339917128,DB0126310011906_,1.079053431,-0.264505166,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,posaconazole,DB01263
,187824,DB01101,10040849,81,7508,15,3893,7.89834526510848e-05,2.799765337,1.598662325,5.239341231,0.000651933,DB0110110040849_,7.335569044,1.029535605,female,10040849,Skin fissures,10040785,Skin and subcutaneous tissue disorders,Skin,capecitabine,DB01101
,187846,DB00005,10072850,76,128006,27,42392,0.733238318,0.932181397,0.593736116,1.504900741,0.845203227,DB0000510072850_,0.168178175,-0.070227851,NA,10072850,Sensitivity to weather change,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,187881,DB06273,10037844,248,4847,56,1354,0.175446625,1.23706814,0.916042966,1.694998006,0.317942121,DB0627310037844_,1.145885921,0.212744177,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,tocilizumab,DB06273
,187882,DB06273,10042128,49,5046,6,1404,0.049609023,2.271989112,0.969596859,6.504532834,0.124282613,DB0627310042128_,2.085197169,0.820655709,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,tocilizumab,DB06273
,187887,DB00451,10034474,94,47177,31,15388,0.917616571,0.989049405,0.652523418,1.536808778,0.963386915,DB0045110034474_,0.037300167,-0.011010994,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,levothyroxine,DB00451
,187894,DB06262,10005734,167,3633,204,4110,0.488982531,0.926090969,0.746518306,1.147727758,0.652422465,DB0626210005734_,0.427062975,-0.076782811,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,droxidopa,DB06262
,187902,DB00087,10035528,55,1314,22,725,0.226149752,1.379176253,0.819511956,2.39572118,0.381035623,DB0008710035528_,0.96486241,0.321486403,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,alemtuzumab,DB00087
,187904,DB08910,10011224,194,16550,175,17313,0.157945817,1.159673336,0.939370298,1.432462819,0.294711849,DB0891010011224_,1.221757184,0.148138358,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,187906,DB00030,10053762,43,2163,40,1781,0.579951407,0.885175938,0.559208084,1.403984851,0.728594706,DB0003010053762_,0.316637661,-0.121968854,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin human,DB00030
,187915,DB00374,10062352,64,17652,27,5697,0.270491931,0.765021922,0.480318766,1.249289058,0.433185954,DB0037410062352_,0.836588189,-0.267850789,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,187934,DB08910,10061623,284,16460,318,17170,0.410761487,0.931578379,0.789864062,1.098324082,0.58013356,DB0891010061623_,0.544496926,-0.070874949,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,187936,DB11093,10033371,67,1590,15,645,0.045354955,1.811543097,1.014784174,3.441103149,0.116268103,DB1109310033371_,2.15185652,0.594179022,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,calcium citrate,DB11093
,187954,DB00924,10030124,84,10078,26,4225,0.207603206,1.354361222,0.861980849,2.194799239,0.358390271,DB0092410030124_,1.026132745,0.30332992,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,187967,DB08910,10005396,30,16714,24,17464,0.343321152,1.306075924,0.73782464,2.335418262,0.512593026,DB0891010005396_,0.66827307,0.267027164,NA,10005396,Blood calcium increased,10022891,Investigations,Inv,pomalidomide,DB08910
,187972,DB08910,10000060,85,16659,78,17410,0.43263273,1.138864843,0.826969924,1.570211206,0.601059823,DB0891010000060_,0.509060811,0.130032014,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,187975,DB00410,10037660,52,1553,23,986,0.185261543,1.435236456,0.856594164,2.473680077,0.33053451,DB0041010037660_,1.107044208,0.361329613,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,mupirocin,DB00410
,187984,DB00641,10013774,44,14080,14,12461,0.000509105,2.781235859,1.495056361,5.497541753,0.003133915,DB0064110013774_,5.765472124,1.022895383,female,10013774,Dry eye,10015919,Eye disorders,Eye,simvastatin,DB00641
,187987,DB00695,10015946,32,28017,21,20507,0.781385739,1.115380668,0.623410808,2.035826835,0.880938299,DB0069510015946_,0.126767691,0.109195753,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,furosemide,DB00695
,187995,DB00338,10013754,109,33565,53,22219,0.06501234,1.361400622,0.971349762,1.928649387,0.152467622,DB0033810013754_,1.880803019,0.308514039,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,188003,DB14513,10020642,54,7123,27,3537,1,0.993119967,0.613516958,1.642832324,1,DB1451310020642_,0,-0.006903809,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,magnesium,DB14513
,188018,DB00575,10069327,41,5203,20,3809,0.152983116,1.500692957,0.857680875,2.708365748,0.288158595,DB0057510069327_,1.244244272,0.405926973,NA,10069327,Product quality issue,10077536,Product issues,Prod,clonidine,DB00575
,188029,DB00567,10008531,46,4473,9,2072,0.013194198,2.367332816,1.142103011,5.511592083,0.044402983,DB0056710008531_,3.11444862,0.861763927,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,188030,DB00956,10008531,40,5774,15,3452,0.126594945,1.594197656,0.860113167,3.111515915,0.250917931,DB0095610008531_,1.382629363,0.466370573,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,188038,DB08877,10061428,44,3245,77,3152,0.001762067,0.555104931,0.373020366,0.817152561,0.008758687,DB0887710061428_,4.737709326,-0.588598119,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ruxolitinib,DB08877
,188045,DB00540,10012735,92,2391,23,1068,0.013170873,1.786442882,1.113984711,2.974627328,0.044347197,DB0054010012735_,3.11570577,0.580226426,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,nortriptyline,DB00540
,188066,DB00497,10048948,37,19230,16,16359,0.026466478,1.967178302,1.06726968,3.789337995,0.076789159,DB0049710048948_,2.566691807,0.676600182,NA,10048948,Bedridden,10041244,Social circumstances,SocCi,oxycodone,DB00497
,188119,DB08910,10017412,60,16684,75,17413,0.302224189,0.834960971,0.584082185,1.189198481,0.468559797,DB0891010017412_,0.75809155,-0.180370296,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,pomalidomide,DB08910
,188121,DB00193,10076309,139,19181,61,8641,0.938889119,1.02656445,0.753582501,1.41247511,0.978556296,DB0019310076309_,0.021676961,0.026217742,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,188122,DB00497,10076309,115,19152,89,16286,0.526555717,1.098736158,0.825230072,1.467013289,0.684323279,DB0049710076309_,0.379324843,0.094160572,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,188123,DB00813,10076309,82,10490,52,10116,0.019086697,1.520663631,1.060194347,2.198288518,0.059565905,DB0081310076309_,2.820671927,0.419146839,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,188124,DB00996,10076309,395,38558,192,22233,0.058008894,1.186291214,0.995064716,1.418106976,0.13970697,DB0099610076309_,1.968208123,0.170831813,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,188126,DB01592,10061623,46,6230,30,3037,0.221304812,0.747464946,0.460806088,1.229061811,0.375144894,DB0159210061623_,0.980442943,-0.29106787,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,188128,DB00399,10016288,26,6966,33,4965,0.033383251,0.561599845,0.322091187,0.969539316,0.092114082,DB0039910016288_,2.384727447,-0.576965702,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,zoledronic acid,DB00399
,188133,DB00203,10023232,110,13768,39,8899,0.000977752,1.823001216,1.253268249,2.701395091,0.005408296,DB0020310023232_,5.219821193,0.600484163,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,188134,DB00559,10023232,43,9616,14,3292,1,1.051462251,0.563405869,2.083920897,1,DB0055910023232_,0,0.050181815,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,bosentan,DB00559
,188135,DB00203,10023644,34,13844,16,8922,0.314621417,1.369473748,0.735034434,2.658765439,0.482247657,DB0020310023644_,0.729297486,0.314426541,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,sildenafil,DB00203
,188149,DB00316,10039906,530,64944,322,36631,0.298997769,0.92839018,0.806272402,1.070289214,0.464970054,DB0031610039906_,0.765782275,-0.074303182,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,188150,DB00471,10039906,88,14101,42,5423,0.279641839,0.805776434,0.551061046,1.194878653,0.443462186,DB0047110039906_,0.813142743,-0.215948953,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,188158,DB00230,10007882,85,19589,42,8609,0.562482496,0.889436875,0.607046822,1.320990519,0.714727468,DB0023010007882_,0.335853973,-0.117166742,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,pregabalin,DB00230
,188159,DB00230,10016454,50,19624,12,8639,0.071508125,1.834241535,0.962549351,3.785674458,0.163891621,DB0023010016454_,1.808549918,0.606631064,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,188165,DB00230,10042609,49,19625,13,8638,0.127954304,1.659011065,0.885745053,3.335120068,0.252776907,DB0023010042609_,1.375247969,0.506221681,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,pregabalin,DB00230
,188176,DB00295,10016825,41,14622,21,9581,0.435482666,1.279268552,0.73813111,2.280255462,0.603933936,DB0029510016825_,0.504290464,0.246288471,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,morphine,DB00295
,188177,DB11089,10016825,57,10118,26,8381,0.01088727,1.815870051,1.122126129,3.011478175,0.0380953,DB1108910016825_,3.267664356,0.59656472,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,docusate,DB11089
,188193,DB00390,10054112,86,4059,41,3260,0.00666588,1.684546707,1.14475928,2.514300855,0.025773945,DB0039010054112_,3.658391172,0.521496511,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,digoxin,DB00390
,188194,DB00559,10054112,374,9285,142,3164,0.279505884,0.897523616,0.734626841,1.10132658,0.443340202,DB0055910054112_,0.813417854,-0.108115845,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,bosentan,DB00559
,188195,DB01233,10054112,40,3381,28,1698,0.196162812,0.717477347,0.430095534,1.212128894,0.344419993,DB0123310054112_,1.065893456,-0.332013903,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,metoclopramide,DB01233
,188196,DB01240,10054112,461,5290,109,1467,0.152177949,1.1728386,0.941873262,1.470473536,0.286974738,DB0124010054112_,1.248361088,0.159426964,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,epoprostenol,DB01240
,188205,DB01075,10047302,43,19905,36,11061,0.077565822,0.663719956,0.416081505,1.064464593,0.174238222,DB0107510047302_,1.747331822,-0.409894971,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,188207,DB00264,10002198,62,29545,38,24854,0.132268667,1.37251514,0.901749319,2.113626248,0.259018954,DB0026410002198_,1.350854038,0.316644925,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,metoprolol,DB00264
,188237,DB00231,10070863,182,3114,134,2005,0.259941838,0.874530042,0.690695503,1.109453022,0.421191666,DB0023110070863_,0.864667285,-0.134068632,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,temazepam,DB00231
,188243,DB00091,10016322,59,5451,16,2654,0.035679677,1.79526701,1.017162639,3.349229509,0.096839313,DB0009110016322_,2.334702246,0.585153763,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,188305,DB00482,10064848,48,8211,25,3046,0.186072616,0.712277307,0.429704798,1.207750129,0.331565231,DB0048210064848_,1.103930714,-0.339287967,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,celecoxib,DB00482
,188306,DB00864,10064848,45,6824,41,8351,0.192228625,1.343124266,0.858896819,2.105680977,0.339468744,DB0086410064848_,1.0803734,0.294998442,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,tacrolimus,DB00864
,188315,DB00060,10039906,207,9301,54,2411,0.938445171,0.99367493,0.730578051,1.371469612,0.978144719,DB0006010039906_,0.022097646,-0.006345158,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,interferon beta-1a,DB00060
,188316,DB00181,10039906,205,9651,152,5719,0.040551477,0.799228164,0.643057977,0.994995267,0.106745552,DB0018110039906_,2.237307294,-0.224108812,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,188317,DB00451,10039906,339,46932,161,15258,0.000111113,0.684550379,0.565289411,0.831791868,0.000873224,DB0045110039906_,7.043318473,-0.378993038,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,188318,DB00476,10039906,337,16920,127,6050,0.631984763,0.948812867,0.76969747,1.175551025,0.770702398,DB0047610039906_,0.260452975,-0.05254369,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,188319,DB00697,10039906,87,6009,30,1776,0.505409885,0.85716171,0.558035532,1.349712781,0.666355811,DB0069710039906_,0.4059315,-0.154128685,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,188320,DB00706,10039906,6,1069,94,15831,1,0.945268252,0.337533232,2.142520494,1,DB0070610039906_,0,-0.056286527,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,188321,DB00745,10039906,54,2523,20,1063,0.700364178,1.137530286,0.666008825,2.016727205,0.819893664,DB0074510039906_,0.198580626,0.128859496,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,modafinil,DB00745
,188365,DB09140,10000087,110,3631,23,1775,0.000104652,2.337657398,1.475102279,3.854780142,0.000829795,DB0914010000087_,7.094331284,0.849149316,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,oxygen,DB09140
,188368,DB00678,10011781,83,15516,12,10712,2.94620616817947e-09,4.77492689,2.591411589,9.616984318,7.4570081011649e-08,DB0067810011781_,16.41152647,1.563378663,female,10011781,Cystitis,10021881,Infections and infestations,Infec,losartan,DB00678
,188369,DB00820,10011781,44,11871,9,5807,0.01256113,2.391425034,1.151154849,5.575457234,0.042701918,DB0082010011781_,3.153511452,0.871889437,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,tadalafil,DB00820
,188370,DB01136,10011781,50,9834,12,11103,6.57554029235395e-08,4.703550533,2.468296985,9.710453391,1.23800988018589e-06,DB0113610011781_,13.6020054,1.548317656,female,10011781,Cystitis,10021881,Infections and infestations,Infec,carvedilol,DB01136
,188373,DB00678,10013971,75,15524,56,10668,0.656392536,0.920352801,0.641782475,1.326455303,0.789930994,DB0067810013971_,0.235809687,-0.082998203,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,188374,DB00678,10020993,55,15544,49,10675,0.194340452,0.770870316,0.514483527,1.157922076,0.342157392,DB0067810020993_,1.072484436,-0.260235121,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,188378,DB01240,10028334,98,5653,23,1553,0.577163956,1.170526142,0.73436114,1.939108804,0.726267905,DB0124010028334_,0.319836317,0.157453342,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,epoprostenol,DB01240
,188384,DB00030,10037844,35,2171,24,1797,0.512245645,1.207048409,0.694947441,2.129651231,0.672462319,DB0003010037844_,0.3968092,0.188178048,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,insulin human,DB00030
,188385,DB09140,10046571,125,3616,22,1776,1.62195169403901e-06,2.790206348,1.75653803,4.628195673,2.20781979688324e-05,DB0914010046571_,10.72091995,1.026115553,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,oxygen,DB09140
,188398,DB00820,10054112,485,11430,164,5652,2.39357384870844e-05,1.462328877,1.218843724,1.761585079,0.000232631,DB0082010054112_,8.3660565,0.380030286,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,tadalafil,DB00820
,188409,DB00678,10056819,47,15552,27,10697,0.4796737,1.197288983,0.730039894,2.000471983,0.644595118,DB0067810056819_,0.439132884,0.18005982,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,188419,DB00678,10062244,46,15553,19,10705,0.075965585,1.666356561,0.95668332,3.013438822,0.171426953,DB0067810062244_,1.763598032,0.510639543,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,188420,DB00695,10062244,86,27963,37,20491,0.006021933,1.703217479,1.14536457,2.577517443,0.023732888,DB0069510062244_,3.740893495,0.532519097,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,188435,DB00030,10069339,42,2164,50,1771,0.089559665,0.687521587,0.442763157,1.062935207,0.194520548,DB0003010069339_,1.637217478,-0.374662051,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,insulin human,DB00030
,188436,DB00588,10069339,156,16368,120,8348,0.000865755,0.66301658,0.518472327,0.849651502,0.004892263,DB0058810069339_,5.320100345,-0.410955281,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,fluticasone propionate,DB00588
,188437,DB00682,10069339,255,19204,377,15987,1.32325277745204e-12,0.563102077,0.47779226,0.662786852,5.85058019433587e-11,DB0068210069339_,23.56189519,-0.574294358,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,warfarin,DB00682
,188438,DB00820,10069339,113,11802,99,5717,2.45399173366706e-05,0.552903471,0.417600645,0.733092094,0.000237712,DB0082010069339_,8.344450367,-0.592571847,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,tadalafil,DB00820
,188439,DB01136,10069339,281,9603,352,10763,0.182116254,0.894740378,0.760264957,1.05222818,0.326529722,DB0113610069339_,1.119234302,-0.111221684,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,carvedilol,DB01136
,188440,DB01240,10069339,79,5672,40,1536,0.002194163,0.53491012,0.35954859,0.80675515,0.010491749,DB0124010069339_,4.55716618,-0.625656546,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,epoprostenol,DB01240
,188441,DB09140,10069339,81,3660,48,1750,0.254003643,0.806917097,0.555046009,1.184004909,0.414585554,DB0914010069339_,0.880475922,-0.214534346,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,oxygen,DB09140
,188445,DB00555,10001949,46,7001,19,3467,0.597285237,1.198900533,0.687527822,2.170334259,0.742475406,DB0055510001949_,0.297765533,0.181404914,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,lamotrigine,DB00555
,188447,DB01373,10001949,77,22643,24,7357,0.908330247,1.042452687,0.651338965,1.725517862,0.958996855,DB0137310001949_,0.041867483,0.04157629,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,calcium,DB01373
,188448,DB13961,10001949,54,9403,26,6388,0.17054278,1.410943188,0.867271944,2.349879207,0.311570251,DB1396110001949_,1.166130442,0.344258408,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,188449,DB00571,10027175,74,5049,22,2587,0.022749679,1.723345529,1.05566353,2.920994671,0.068297107,DB0057110027175_,2.683887873,0.544267477,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,propranolol,DB00571
,188450,DB01373,10033295,58,22662,12,7369,0.165911836,1.571588903,0.834300961,3.21715353,0.305339161,DB0137310033295_,1.186332116,0.452087148,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,188451,DB00571,10039906,81,5042,29,2580,0.104775196,1.429173735,0.921984428,2.272355909,0.218157162,DB0057110039906_,1.522539549,0.35709647,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,propranolol,DB00571
,188452,DB01373,10039906,119,22601,55,7326,0.033676602,0.701341037,0.504781833,0.984968942,0.09272398,DB0137310039906_,2.378128157,-0.354761009,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,calcium,DB01373
,188453,DB13961,10039906,71,9386,49,6365,0.925862735,0.982603231,0.672254075,1.446461787,0.968399911,DB1396110039906_,0.032110146,-0.017549871,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,fish oil,DB13961
,188476,DB00374,10057688,85,17631,22,5702,0.429529609,1.249510792,0.773577836,2.09993824,0.597997128,DB0037410057688_,0.514169327,0.222752108,NA,10057688,Catheter site discharge,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,188477,DB00065,10061822,125,9339,28,4929,1.53536650477615e-05,2.356069922,1.551373111,3.693519106,0.000158201,DB0006510061822_,8.751643352,0.856994944,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,188487,DB06724,10015150,63,7866,20,3899,0.100457685,1.561330322,0.929817554,2.730729471,0.211521628,DB0672410015150_,1.553428024,0.445538228,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,calcium carbonate,DB06724
,188488,DB14513,10015150,55,7122,24,3540,0.633461878,1.139054292,0.692006631,1.927551169,0.772036715,DB1451310015150_,0.258723172,0.13019835,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,magnesium,DB14513
,188490,DB13961,10021519,37,9420,14,6400,0.063573022,1.795505404,0.947141311,3.598143213,0.149920767,DB1396110021519_,1.897648343,0.585286545,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,188534,DB00186,10016334,51,16850,15,9993,0.015068498,2.016341525,1.115327905,3.863380454,0.049503246,DB0018610016334_,3.00571703,0.701284743,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,188535,DB00338,10016334,103,33571,41,22231,0.006176349,1.663580042,1.147385447,2.4521787,0.02422161,DB0033810016334_,3.720510081,0.508971932,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,188542,DB00295,10029410,32,14631,20,9582,1,1.047860187,0.580832798,1.934437321,1,DB0029510029410_,0,0.046750167,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,morphine,DB00295
,188565,DB00537,10008190,45,7512,22,4276,0.611734062,1.164331925,0.683617229,2.038967056,0.753770383,DB0053710008190_,0.282667489,0.152147468,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,188567,DB00490,10012378,175,3895,48,1528,0.032684973,1.430217036,1.027583335,2.022965789,0.090591902,DB0049010012378_,2.40139045,0.357826206,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,buspirone,DB00490
,188607,DB00734,10049119,8,4042,206,4696,4.65467012897429e-44,0.045125361,0.019212718,0.09078111,2.10944835069119e-41,DB0073410049119_,93.65956234,-3.098310852,male,10049119,Emotional distress,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,188618,DB00203,10053505,82,13796,26,8912,0.001054932,2.037271358,1.29550245,3.303046932,0.005760053,DB0020310053505_,5.156808561,0.711611343,NA,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,188633,DB00710,10037844,62,2344,6,195,0.646131319,0.859695161,0.366816246,2.463428211,0.781649463,DB0071010037844_,0.246348896,-0.151177416,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ibandronate,DB00710
,188660,DB00588,10018627,33,16491,30,8438,0.023622109,0.562832052,0.332513767,0.956108963,0.070341806,DB0058810018627_,2.654388972,-0.574774004,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,fluticasone propionate,DB00588
,188704,DB00046,10069339,112,5347,166,4526,5.69875767561679e-06,0.571141971,0.443829248,0.732721194,6.62795776564546e-05,DB0004610069339_,9.621628738,-0.560117464,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,insulin lispro,DB00046
,188705,DB00047,10069339,179,9106,290,8228,8.96617275886536e-10,0.557750893,0.459200375,0.675994775,2.51387574364561e-08,DB0004710069339_,17.49885506,-0.583842845,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,insulin glargine,DB00047
,188706,DB00275,10069339,66,1994,48,1189,0.325195136,0.819956737,0.552665323,1.224026065,0.493604789,DB0027510069339_,0.706020103,-0.1985037,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,olmesartan,DB00275
,188707,DB01115,10069339,66,3534,102,2166,6.53325976219548e-09,0.396647588,0.285142571,0.548590455,1.52781790791199e-07,DB0111510069339_,15.69425514,-0.92470708,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,nifedipine,DB01115
,188740,DB00316,10016275,81,65393,12,36941,7.15706935164718e-07,3.813081937,2.067771772,7.684597133,1.06495085144662e-05,DB0031610016275_,11.44999682,1.33843777,female,10016275,Fear,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,188743,DB00669,10020937,73,6304,10,1087,0.63915309,1.258704018,0.644344166,2.743229006,0.776220989,DB0066910020937_,0.25331802,0.230082635,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,sumatriptan,DB00669
,188760,DB01229,10007559,48,5693,9,2700,0.006683862,2.529192848,1.225126964,5.871883953,0.025822784,DB0122910007559_,3.656498061,0.92790022,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,paclitaxel,DB01229
,188801,DB00046,10028372,28,5431,44,4648,0.012463042,0.544656524,0.325986701,0.8962283,0.042431327,DB0004610028372_,3.159868351,-0.607599915,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin lispro,DB00046
,188893,DB00996,10003445,43,38910,30,22395,0.465746819,0.824980083,0.505519323,1.362356016,0.632541632,DB0099610003445_,0.45800924,-0.192396034,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,188898,DB00996,10019641,31,38922,39,22386,0.001147129,0.457170133,0.27571817,0.752141612,0.006172421,DB0099610019641_,5.087664147,-0.782699675,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,gabapentin,DB00996
,188913,DB00341,10003481,40,11365,30,5038,0.036929397,0.591074894,0.358578216,0.98394109,0.099450766,DB0034110003481_,2.308092576,-0.525812545,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,cetirizine,DB00341
,188936,DB00987,10020635,36,2068,41,2887,0.415468552,1.225728529,0.758237794,1.973734593,0.584686829,DB0098710020635_,0.53667891,0.203535385,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,cytarabine,DB00987
,188975,DB00863,10067482,47,10626,16,5824,0.112950073,1.609969859,0.895542575,3.044750977,0.230513038,DB0086310067482_,1.467447855,0.476215458,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,188977,DB05676,10015137,45,47084,18,25311,0.354820264,1.343928229,0.762403654,2.467303495,0.524650558,DB0567610015137_,0.645022843,0.29559684,NA,10015137,Eructation,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,188978,DB05676,10016766,220,46909,181,25148,2.52263875972425e-05,0.651594449,0.532495313,0.798201587,0.000243375,DB0567610016766_,8.320906475,-0.428332921,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,188979,DB05676,10063541,37,47092,32,25297,0.05736141,0.621097273,0.376384515,1.030177346,0.138468936,DB0567610063541_,1.97710927,-0.47626757,NA,10063541,Bowel movement irregularity,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,188980,DB00758,10000059,88,8212,101,9973,0.71381815,1.058093254,0.784676757,1.424595878,0.830288509,DB0075810000059_,0.185982038,0.056468471,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,188981,DB00868,10000059,37,2947,18,1628,0.777133816,1.135531169,0.627950237,2.126017611,0.878512755,DB0086810000059_,0.129524852,0.127100532,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,benzonatate,DB00868
,188984,DB00341,10029331,105,11300,71,4997,0.00667079,0.653994206,0.478412739,0.898452282,0.025783652,DB0034110029331_,3.658014645,-0.424656787,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,188988,DB00868,10047700,86,2898,36,1610,0.179578268,1.327082711,0.884856543,2.026523493,0.323346675,DB0086810047700_,1.129030234,0.282983083,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,benzonatate,DB00868
,188992,DB00158,10061822,72,16743,35,8069,1,0.991404784,0.652618272,1.531595708,1,DB0015810061822_,0,-0.008632368,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,188993,DB00207,10061822,48,9032,22,5433,0.323583668,1.312400775,0.776031728,2.285811394,0.492014504,DB0020710061822_,0.709247083,0.271858112,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,189067,DB00158,10047943,38,16777,30,8074,0.051010242,0.609590696,0.367470881,1.01964392,0.126916012,DB0015810047943_,2.064229732,-0.494967538,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,folic acid,DB00158
,189075,DB00421,10040753,146,8757,12,5240,1.21208085491457e-17,7.280436195,4.037940013,14.43155089,1.00345024476944e-15,DB0042110040753_,34.53533209,1.985190777,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,spironolactone,DB00421
,189077,DB00588,10043417,44,16480,15,8453,0.214683243,1.504556276,0.820738979,2.912409393,0.36707405,DB0058810043417_,1.002191681,0.408498021,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,189078,DB00722,10043417,53,25350,44,25988,0.311057511,1.234853411,0.811962714,1.886196861,0.478561769,DB0072210043417_,0.736969988,0.210952268,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,189098,DB00999,10068319,154,21276,45,12194,4.24121252787006e-05,1.961354584,1.397747836,2.800926841,0.000383731,DB0099910068319_,7.865569876,0.673635349,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,189106,DB00338,10060933,108,33566,65,22207,0.586445761,1.09927788,0.800348333,1.520007937,0.733667777,DB0033810060933_,0.309698972,0.094653491,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,189107,DB00471,10060933,39,14150,16,5449,0.880255853,0.93865155,0.512087482,1.800788172,0.949771523,DB0047110060933_,0.051533826,-0.063310955,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,189110,DB00343,10036653,44,8692,11,5084,0.010964358,2.339494249,1.187608306,5.028314135,0.038314032,DB0034310036653_,3.261939087,0.849934773,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,189125,DB00153,10069339,114,7309,83,3356,0.001921562,0.630677134,0.469679327,0.849836488,0.009420547,DB0015310069339_,4.664862095,-0.460961221,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ergocalciferol,DB00153
,189126,DB06724,10069339,195,7734,190,3729,2.48411895268325e-11,0.494863293,0.40156846,0.609948928,8.89578565003804e-10,DB0672410069339_,20.84027329,-0.703473731,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,calcium carbonate,DB06724
,189134,DB06228,10018627,25,15887,50,16026,0.005219865,0.504387827,0.298852537,0.831349264,0.02117675,DB0622810018627_,3.85485142,-0.684409809,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,rivaroxaban,DB06228
,189155,DB00482,10033775,78,8181,42,3029,0.062412754,0.687628365,0.465494034,1.028369216,0.147954477,DB0048210033775_,1.910850639,-0.374506754,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,189156,DB00706,10033775,13,1062,102,15823,0.034351432,1.898894728,0.974393565,3.408394026,0.094113757,DB0070610033775_,2.363251047,0.641271995,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,tamsulosin,DB00706
,189161,DB00275,10037844,48,2012,38,1199,0.214662473,0.752830538,0.478531159,1.191696871,0.367069128,DB0027510037844_,1.002205089,-0.283915126,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,olmesartan,DB00275
,189162,DB00373,10037844,33,1799,23,1264,1,1.008093885,0.571179848,1.807317657,1,DB0037310037844_,0,0.008061305,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,timolol,DB00373
,189184,DB00381,10024774,72,29288,57,22830,0.929474387,0.984628846,0.685605288,1.419778487,0.970957565,DB0038110024774_,0.029472514,-0.015490515,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,189190,DB01076,10003553,129,25618,34,25549,3.01674273335105e-14,3.783508391,2.574726983,5.698387149,1.65889294447976e-12,DB0107610003553_,27.12487064,1.330651725,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,189191,DB00230,10000060,102,19572,32,8619,0.109535358,1.403722178,0.93458903,2.160456792,0.225390392,DB0023010000060_,1.489921303,0.339127407,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,189195,DB01098,10033557,70,8079,27,7182,0.000138677,2.304532842,1.457236782,3.742225239,0.001054265,DB0109810033557_,6.854911398,0.834877984,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,rosuvastatin,DB01098
,189196,DB00285,10003658,51,10900,29,3689,0.028419006,0.595212031,0.369548501,0.975481412,0.081203779,DB0028510003658_,2.510793495,-0.518837583,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,venlafaxine,DB00285
,189203,DB00343,10037423,86,8650,41,5054,0.31004785,1.225497629,0.833953433,1.826987167,0.477492763,DB0034310037423_,0.739206274,0.203346989,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,189218,DB00377,10002855,49,1070,20,703,0.079403404,1.609278671,0.929726392,2.884017387,0.177423256,DB0037710002855_,1.729217123,0.475786048,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,palonosetron,DB00377
,189241,DB01067,10016322,46,4315,38,4785,0.189030006,1.342329327,0.852668255,2.12443853,0.335323348,DB0106710016322_,1.092659994,0.294406408,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,189242,DB01592,10016322,98,6178,32,3035,0.048045229,1.504420599,0.997539528,2.323725638,0.121435535,DB0159210016322_,2.108371733,0.40840784,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,189246,DB01248,10006002,76,2624,18,1356,0.001927118,2.181549852,1.285686815,3.89260166,0.009446905,DB0124810006002_,4.66206811,0.780035565,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,docetaxel,DB01248
,189247,DB00019,10008469,34,18978,16,9513,0.881977572,1.06518399,0.57179974,2.067807676,0.950618512,DB0001910008469_,0.050642441,0.063147545,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,189248,DB00515,10051055,19,1851,33,2118,0.162895136,0.65887712,0.35268444,1.197853329,0.301241683,DB0051510051055_,1.199842404,-0.417218226,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,cisplatin,DB00515
,189256,DB00338,10005728,41,33633,34,22238,0.346118408,0.797336039,0.493528326,1.295737167,0.515539318,DB0033810005728_,0.662541707,-0.22647906,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,omeprazole,DB00338
,189258,DB00999,10005728,63,21367,29,12210,0.385541955,1.24143951,0.787251574,2.00055869,0.555660053,DB0099910005728_,0.587598588,0.216271601,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,189263,DB00193,10025082,47,19273,11,8691,0.047109658,1.926711697,0.984328033,4.121523325,0.11966923,DB0019310025082_,2.123023755,0.655814766,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,189278,DB00758,10003246,41,8259,20,10054,0.000683892,2.495432517,1.427592623,4.499518306,0.004013865,DB0075810003246_,5.518000577,0.914462068,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,clopidogrel,DB00758
,189310,DB00656,10017955,46,11967,46,6573,0.004414286,0.549309521,0.356557076,0.84618771,0.018489286,DB0065610017955_,3.990563828,-0.599093206,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,189318,DB00734,10039897,56,3994,81,4821,0.341445492,0.834528241,0.581171167,1.191092458,0.510618994,DB0073410039897_,0.672131576,-0.180888694,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,189333,DB01068,10007515,285,13478,146,6694,0.756728049,0.969482663,0.789650547,1.194456541,0.863836772,DB0106810007515_,0.146371449,-0.030992687,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,clonazepam,DB01068
,189338,DB00514,10013968,63,2103,46,1490,0.921487432,0.970346563,0.648974683,1.460421337,0.965261115,DB0051410013968_,0.035356629,-0.03010199,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dextromethorphan,DB00514
,189353,DB00472,10029148,45,10714,13,4299,0.382085973,1.388868794,0.735394155,2.80948986,0.552169216,DB0047210029148_,0.593900729,0.328489599,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,fluoxetine,DB00472
,189355,DB01068,10029148,46,13717,15,6825,0.174072089,1.525814798,0.835864374,2.944522499,0.316259537,DB0106810029148_,1.151192081,0.422528561,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,clonazepam,DB01068
,189359,DB00273,10076309,154,8327,48,2145,0.253432888,0.826468583,0.591917565,1.172109182,0.413962432,DB0027310076309_,0.881980052,-0.190593375,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,topiramate,DB00273
,189360,DB00316,10076309,633,64841,273,36680,0.000171864,1.311655923,1.135634575,1.518173178,0.001269121,DB0031610076309_,6.669430834,0.271290403,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,189361,DB00471,10076309,97,14092,33,5432,0.623388673,1.133029182,0.755176911,1.739098936,0.763455716,DB0047110076309_,0.269900157,0.124894738,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,189362,DB00472,10076309,82,10677,35,4277,0.758414451,0.938503335,0.623465755,1.439320302,0.865137628,DB0047210076309_,0.144866677,-0.063468869,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,189363,DB00555,10076309,64,6983,21,3465,0.105845527,1.512188962,0.909533135,2.611542908,0.219941475,DB0055510076309_,1.51439379,0.413558245,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lamotrigine,DB00555
,189364,DB00641,10076309,125,13999,66,12409,0.00059971,1.678788872,1.23486383,2.300083894,0.003594841,DB0064110076309_,5.628255636,0.518072624,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,189365,DB00736,10076309,113,10478,54,5499,0.623490869,1.098211482,0.785919569,1.550987156,0.763522851,DB0073610076309_,0.269812226,0.093682931,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,esomeprazole,DB00736
,189367,DB01068,10076309,120,13643,49,6791,0.252214034,1.21897588,0.866270467,1.738451923,0.412327126,DB0106810076309_,0.885938249,0.198011064,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,189373,DB00451,10076308,282,46989,74,15345,0.09591948,1.244468833,0.959582869,1.631262427,0.204646391,DB0045110076308_,1.58647171,0.218708798,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,189374,DB01068,10076308,98,13665,54,6786,0.545761624,0.901240015,0.639185415,1.282407229,0.700490468,DB0106810076308_,0.35597452,-0.10398367,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,189388,DB01267,10022437,28,2824,41,3674,0.714519626,0.888523081,0.527761664,1.476010968,0.830796075,DB0126710022437_,0.185370912,-0.118194654,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,189394,DB06605,10007882,101,13972,79,12954,0.262704301,1.185322451,0.873405989,1.613423454,0.42445109,DB0660510007882_,0.856958499,0.170014848,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,apixaban,DB06605
,189397,DB00321,10048393,98,7349,15,2835,0.000298317,2.520053151,1.452601518,4.681478067,0.002008518,DB0032110048393_,6.210358126,0.924279993,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,189411,DB00471,10023547,47,14142,24,5441,0.287947733,0.753458673,0.451013661,1.28961922,0.452931161,DB0047110023547_,0.792015127,-0.283081109,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,montelukast,DB00471
,189438,DB00115,10006093,31,18394,22,10450,0.474841422,0.800552329,0.448574697,1.451918351,0.640497571,DB0011510006093_,0.445509949,-0.222453378,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,cyanocobalamin,DB00115
,189441,DB06228,10028997,25,15887,36,16040,0.199963138,0.701143058,0.40324513,1.201375203,0.348936538,DB0622810028997_,1.052865213,-0.355043335,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,rivaroxaban,DB06228
,189476,DB06637,10036018,78,6084,14,2005,0.03793734,1.835864373,1.028641879,3.520638645,0.101494452,DB0663710036018_,2.287751143,0.607515419,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,dalfampridine,DB06637
,189500,DB09037,10002034,61,2465,47,2788,0.051688608,1.467820333,0.982880701,2.204070375,0.128233607,DB0903710002034_,2.053901626,0.383778534,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,pembrolizumab,DB09037
,189513,DB01104,10051076,34,15429,21,7265,0.315647484,0.762336134,0.429555868,1.383389888,0.483293374,DB0110410051076_,0.727131411,-0.2713677,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,189514,DB00734,10057362,76,3974,131,4771,0.013316082,0.696533415,0.516306835,0.93415855,0.044724809,DB0073410057362_,3.107226914,-0.361639512,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,189560,DB00399,10019974,50,6942,29,4969,0.423281451,1.234095437,0.764689147,2.025723972,0.592152479,DB0039910019974_,0.523991111,0.210338262,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,zoledronic acid,DB00399
,189585,DB00230,10013946,64,19610,29,8622,0.910348604,0.970314349,0.616042091,1.562125345,0.959579421,DB0023010013946_,0.041260194,-0.030135189,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,189599,DB00316,10035742,99,65375,104,36849,1.35724473798167e-05,0.536542072,0.403166744,0.713672227,0.000142019,DB0031610035742_,8.859549562,-0.6226103,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,189621,DB00480,10053762,161,67267,141,67521,0.249390707,1.146153592,0.908318326,1.447637381,0.408807904,DB0048010053762_,0.894509906,0.136411634,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,189626,DB00425,10070863,763,11932,381,7103,0.006706434,1.192097365,1.049036991,1.356476477,0.025887162,DB0042510070863_,3.654008115,0.175714248,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,189627,DB00868,10070863,38,2946,17,1629,0.571143185,1.236002345,0.678404067,2.34291344,0.721482462,DB0086810070863_,0.326447209,0.211882256,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,benzonatate,DB00868
,189681,DB00316,10071408,202,65272,10,36943,1.36776367116967e-27,11.43305148,6.089263421,24.20197552,2.57718050872364e-25,DB0031610071408_,56.61793135,2.436508413,female,10071408,Maternal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,189721,DB00295,10042458,46,14617,30,9572,1,1.004109242,0.619906227,1.648730181,1,DB0029510042458_,0,0.004100822,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,morphine,DB00295
,189733,DB00215,10062355,46,11057,32,5244,0.113593073,0.681766555,0.424360441,1.107640239,0.231519709,DB0021510062355_,1.463090271,-0.383067975,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,189760,DB00921,10039906,42,5803,39,4864,0.655866109,0.902672342,0.568704507,1.435795507,0.789460122,DB0092110039906_,0.236405957,-0.102395647,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,buprenorphine,DB00921
,189768,DB00321,10022086,93,7354,13,2837,0.00017813,2.75938295,1.534194252,5.384408064,0.001307262,DB0032110022086_,6.639820499,1.015007086,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,189772,DB00321,10040047,49,7398,36,2814,0.003357302,0.517740792,0.329119461,0.821487906,0.014806489,DB0032110040047_,4.212689754,-0.658280563,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,amitriptyline,DB00321
,189773,DB00472,10040047,76,10683,37,4275,0.347141007,0.82200574,0.546974522,1.25488854,0.516564843,DB0047210040047_,0.660554456,-0.196007902,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,fluoxetine,DB00472
,189795,DB00335,10028735,42,8424,21,5444,0.367482322,1.292467134,0.747421351,2.300095062,0.537148497,DB0033510028735_,0.621480692,0.256552899,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atenolol,DB00335
,189796,DB00476,10028735,63,17194,10,6167,0.011437163,2.259653636,1.150340784,4.943245212,0.039644709,DB0047610028735_,3.227797782,0.815211543,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,189798,DB00887,10028735,37,2304,18,1797,0.102718701,1.603048976,0.886370754,3.001765505,0.21510206,DB0088710028735_,1.536642665,0.471907426,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bumetanide,DB00887
,189800,DB01068,10028735,65,13698,22,6818,0.137654771,1.470560558,0.893796784,2.507226069,0.266438629,DB0106810028735_,1.322611345,0.38564366,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,189806,DB01039,10043607,30,2943,29,3022,0.896088097,1.062269272,0.614357923,1.839092478,0.956301489,DB0103910043607_,0.044682051,0.060407442,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,fenofibrate,DB01039
,189813,DB01156,10076309,82,13540,42,6286,0.628650198,0.906408996,0.616742066,1.349627461,0.76784714,DB0115610076309_,0.264164602,-0.098264645,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,189840,DB00203,10005851,39,13839,19,8919,0.347989635,1.322868854,0.745698335,2.425307309,0.517575752,DB0020310005851_,0.658599383,0.279802752,NA,10005851,Blood urea increased,10022891,Investigations,Inv,sildenafil,DB00203
,189879,DB00243,10002383,37,1217,43,1583,0.648282443,1.119195536,0.69647503,1.790788221,0.783290998,DB0024310002383_,0.244251008,0.112610156,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,ranolazine,DB00243
,189880,DB01020,10002383,18,1795,34,1844,0.036667147,0.543953675,0.288070635,0.994759625,0.098911735,DB0102010002383_,2.313527389,-0.608891192,NA,10002383,Angina pectoris,10007541,Cardiac disorders,Card,isosorbide mononitrate,DB01020
,189892,DB00243,10035664,14,1240,38,1588,0.015994075,0.471936885,0.235093101,0.895847769,0.051818596,DB0024310035664_,2.960006207,-0.750910021,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ranolazine,DB00243
,189896,DB00722,10062244,67,25336,35,25997,0.001010866,1.964190463,1.28593081,3.047687819,0.005553477,DB0072210062244_,5.193331096,0.675080182,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,189899,DB01076,10062244,73,25674,33,25550,0.00012726,2.201394531,1.439919071,3.430230457,0.000980086,DB0107610062244_,6.927870095,0.789091037,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,189906,DB01267,10012378,42,2810,37,3678,0.086879789,1.485660736,0.929365957,2.383866667,0.189852257,DB0126710012378_,1.661509105,0.395859613,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,189908,DB01267,10025482,29,2823,37,3678,1,1.021170783,0.604113406,1.711042822,1,DB0126710025482_,0,0.020949796,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,189923,DB05679,10047513,38,6893,25,4884,0.799219942,1.076996579,0.632465928,1.86415614,0.891545906,DB0567910047513_,0.11479835,0.074176221,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ustekinumab,DB05679
,189925,DB01068,10012239,26,13737,36,6804,6.50805771209846e-05,0.357738972,0.207199147,0.609742364,0.000551376,DB0106810012239_,7.503094212,-1.027951688,male,10012239,Delusion,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,189931,DB00334,10019070,15,2834,35,2777,0.004215105,0.419995586,0.212612939,0.791336593,0.017825271,DB0033410019070_,4.027138122,-0.867511078,NA,10019070,"Hallucination, auditory",10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,189934,DB00588,10048439,59,16465,11,8457,0.000898907,2.754855762,1.432423172,5.819248279,0.005045972,DB0058810048439_,5.289165041,1.013365086,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,189942,DB05676,10003246,219,46910,116,25213,0.954215542,1.014717728,0.806133723,1.282764631,0.992091273,DB0567610003246_,0.007940167,0.014610473,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,189943,DB05676,10005191,80,47049,24,25305,0.010048363,1.792797741,1.123706952,2.959883173,0.035708946,DB0567610005191_,3.332354024,0.583777383,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,189947,DB00999,10001949,100,21330,44,12195,0.164785124,1.299384406,0.902139921,1.898340186,0.303839008,DB0099910001949_,1.191257298,0.261890618,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,189954,DB01220,10002034,30,1264,37,1099,0.172872704,0.705076893,0.417615864,1.18164338,0.314624133,DB0122010002034_,1.156376582,-0.349448414,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,rifaximin,DB01220
,189961,DB00285,10008531,76,10875,13,3705,0.019645089,1.991749556,1.096279756,3.915788865,0.060946728,DB0028510008531_,2.797755101,0.689013426,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,189963,DB14513,10008531,69,7108,22,3542,0.073521856,1.562826987,0.953274773,2.657656667,0.167391298,DB1451310008531_,1.787421104,0.446496352,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,189965,DB00331,10013496,36,24910,20,20732,0.178923538,1.498080883,0.843993132,2.732112911,0.322554453,DB0033110013496_,1.131483311,0.404184877,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,metformin,DB00331
,189966,DB00999,10013496,52,21378,16,12223,0.031295053,1.858174427,1.043791259,3.4881079,0.087560858,DB0099910013496_,2.43542121,0.619594515,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,189986,DB14513,10038435,47,7130,36,3528,0.060361063,0.646015404,0.408818192,1.028573397,0.144111044,DB1451310038435_,1.93717114,-0.43693193,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,magnesium,DB14513
,189988,DB14513,10053762,200,6977,59,3505,0.000231515,1.702854936,1.263899033,2.323693753,0.001627976,DB1451310053762_,6.420417577,0.532306217,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium,DB14513
,190054,DB00982,10000081,44,3320,29,2072,0.809885095,0.946920114,0.577272592,1.574786391,0.897633603,DB0098210000081_,0.107993308,-0.054540546,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,isotretinoin,DB00982
,190074,DB01202,10069339,70,6644,102,5616,0.00049639,0.580122887,0.420772058,0.795845809,0.003072916,DB0120210069339_,5.785128342,-0.544515324,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,levetiracetam,DB01202
,190075,DB00028,10015150,199,13259,76,5539,0.548832949,1.093849128,0.834082637,1.447037373,0.703282099,DB0002810015150_,0.351997189,0.089702786,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,human immunoglobulin g,DB00028
,190077,DB01109,10015150,47,4365,20,4250,0.001937447,2.288039835,1.326926071,4.083163322,0.009487633,DB0110910015150_,4.657766118,0.827695484,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,heparin,DB01109
,190079,DB00126,10076309,64,10107,29,5916,0.281806092,1.291762364,0.819713481,2.080645565,0.445788307,DB0012610076309_,0.807911087,0.256007459,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ascorbic acid,DB00126
,190080,DB00169,10076309,288,38403,113,18062,0.107046992,1.198690393,0.960337959,1.504664589,0.221693206,DB0016910076309_,1.506460807,0.181229622,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,190081,DB00213,10076309,116,18779,73,13348,0.459256078,1.129514126,0.834837418,1.536583655,0.626621298,DB0021310076309_,0.467412911,0.121787563,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,190082,DB00404,10076309,134,19758,62,9800,0.70366314,1.071999704,0.786783021,1.47445767,0.822250872,DB0040410076309_,0.195709734,0.069525787,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,190083,DB00635,10076309,240,32813,169,23625,0.840696831,1.02247079,0.835674565,1.253271324,0.918632974,DB0063510076309_,0.084868612,0.022222042,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,190084,DB00688,10076309,40,6450,40,5338,0.430969465,0.827612836,0.519564241,1.318330152,0.599393743,DB0068810076309_,0.511836562,-0.189209824,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,mycophenolate mofetil,DB00688
,190086,DB01050,10076309,161,17947,57,9314,0.012070211,1.465850536,1.07613126,2.021559348,0.041329445,DB0105010076309_,3.186180069,0.382435645,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,190087,DB01075,10076309,197,19751,122,10975,0.348068593,0.897273317,0.711388774,1.135405198,0.517593515,DB0107510076309_,0.658565065,-0.108394762,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,190088,DB01109,10076309,32,4380,29,4241,0.8978863,1.068450828,0.62480768,1.833968477,0.956338178,DB0110910076309_,0.044643686,0.066209775,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,heparin,DB01109
,190089,DB01136,10076309,76,9808,70,11045,0.24431661,1.222631084,0.870880124,1.718625557,0.402884852,DB0113610076309_,0.909104485,0.201005163,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,190090,DB01175,10076309,76,10648,26,4866,0.238596218,1.335837117,0.844545696,2.175949777,0.396303419,DB0117510076309_,0.925575152,0.289558149,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,190091,DB06724,10076309,63,7866,19,3900,0.059513364,1.64392117,0.96960011,2.912794955,0.142579299,DB0672410076309_,1.94785695,0.497084346,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium carbonate,DB06724
,190092,DB00028,10014011,185,13273,93,5522,0.144812838,0.827622609,0.640314157,1.075724645,0.27675904,DB0002810014011_,1.284608042,-0.189198015,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,190095,DB00471,10014011,51,14138,41,5424,0.000626159,0.47722631,0.309736536,0.739306665,0.003734111,DB0047110014011_,5.590245499,-0.739764455,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,montelukast,DB00471
,190097,DB00668,10014011,127,9964,70,4233,0.084928382,0.770754563,0.569927277,1.049662473,0.18666632,DB0066810014011_,1.678432642,-0.260385292,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,epinephrine,DB00668
,190098,DB01075,10014011,143,19805,72,11025,0.520827702,1.105632583,0.826381204,1.490241896,0.679857778,DB0107510014011_,0.385871653,0.100417644,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,190103,DB09153,10014011,55,7744,21,5678,0.010136051,1.920221139,1.141102241,3.346900897,0.035957366,DB0915310014011_,3.325421315,0.652440356,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,190108,DB00028,10015929,42,13416,15,5600,0.664683692,1.168737225,0.634384178,2.270833428,0.795900547,DB0002810015929_,0.228281042,0.155923871,NA,10015929,Eye infection,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,190115,DB01075,10015929,44,19904,14,11083,0.074260473,1.74998463,0.940739438,3.459151531,0.168625412,DB0107510015929_,1.78007552,0.559607005,NA,10015929,Eye infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,190155,DB00218,10040753,47,1395,9,941,0.000151975,3.521126871,1.695550864,8.210303664,0.001140031,DB0021810040753_,6.776699842,1.258781072,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,moxifloxacin,DB00218
,190156,DB00575,10040753,48,5196,20,3809,0.035770328,1.759243059,1.022534157,3.134945601,0.09703929,DB0057510040753_,2.332639334,0.564883636,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,clonidine,DB00575
,190176,DB00091,10040753,79,5431,18,2652,0.002221971,2.142957631,1.269151744,3.808761324,0.01059973,DB0009110040753_,4.546926754,0.762186946,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,cyclosporine,DB00091
,190177,DB00126,10040753,215,9956,65,5880,9.37760813730921e-07,1.953442292,1.470774838,2.624590103,1.35322772379452e-05,DB0012610040753_,11.21043282,0.669593094,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,190180,DB00285,10040753,131,10820,21,3697,0.000683973,2.131456151,1.335613641,3.564036011,0.004013892,DB0028510040753_,5.517994023,0.756805385,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,venlafaxine,DB00285
,190181,DB00571,10040753,54,5069,20,2589,0.266091606,1.378975768,0.810015874,2.437643995,0.428213051,DB0057110040753_,0.848134424,0.321341026,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,propranolol,DB00571
,190184,DB00028,10040872,34,13424,21,5594,0.181455059,0.674698623,0.380076533,1.224500253,0.325688567,DB0002810040872_,1.121813669,-0.393489173,NA,10040872,Skin infection,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,190186,DB00169,10040872,32,38659,20,18155,0.371764262,0.751368586,0.416644357,1.386705803,0.541435263,DB0016910040872_,0.613531771,-0.285858954,NA,10040872,Skin infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,190215,DB00281,10014011,89,11369,43,5628,0.926329863,1.024618185,0.703255758,1.513079944,0.968692902,DB0028110014011_,0.03180764,0.02432004,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,lidocaine,DB00281
,190222,DB00028,10025197,44,13414,12,5603,0.239562146,1.531564462,0.794389637,3.188004924,0.397380475,DB0002810025197_,0.922861083,0.426289737,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,human immunoglobulin g,DB00028
,190234,DB00188,10042674,32,7854,29,8799,0.442051312,1.236196644,0.723599718,2.120107121,0.610162197,DB0018810042674_,0.49403046,0.212039443,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,190235,DB00115,10014011,54,18371,22,10450,0.231787393,1.396206819,0.835630592,2.408881927,0.388071699,DB0011510014011_,0.946565166,0.333759144,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,190240,DB00059,10002034,34,793,54,1053,0.442278905,0.83614233,0.522381276,1.322189352,0.610403547,DB0005910002034_,0.493634988,-0.178956429,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,pegaspargase,DB00059
,190242,DB00563,10038063,47,46599,27,15321,0.029912585,0.572333843,0.349085637,0.956002974,0.084527971,DB0056310038063_,2.470672782,-0.558032816,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,methotrexate,DB00563
,190251,DB00512,10069339,395,4342,547,4551,5.931221368388e-05,0.756903696,0.658885319,0.868910261,0.00051081,DB0051210069339_,7.579512968,-0.278519252,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,vancomycin,DB00512
,190252,DB00028,10022004,196,13262,60,5555,0.038082405,1.368220047,1.01794196,1.862246932,0.101763433,DB0002810022004_,2.285104443,0.313510659,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,190259,DB00028,10065473,41,13417,9,5606,0.08708302,1.903383904,0.910448707,4.457113498,0.190209172,DB0002810065473_,1.659630905,0.643633304,NA,10065473,Infusion site irritation,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,190271,DB00921,10008531,37,5808,37,4866,0.483124237,0.837826002,0.515721914,1.361060907,0.6473225,DB0092110008531_,0.434910655,-0.176944835,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,190281,DB00484,10022806,80,2427,56,1724,1,1.014771518,0.707988522,1.46298733,1,DB0048410022806_,0,0.014663481,NA,10022806,Intraocular pressure increased,10022891,Investigations,Inv,brimonidine,DB00484
,190284,DB00905,10022806,39,2679,22,903,0.073450402,0.597620583,0.343564113,1.064315658,0.16727197,DB0090510022806_,1.788134227,-0.514799203,NA,10022806,Intraocular pressure increased,10022891,Investigations,Inv,bimatoprost,DB00905
,190318,DB08910,10037884,60,16684,42,17446,0.047439068,1.493790999,0.989803128,2.27300554,0.120275388,DB0891010037884_,2.117971266,0.401317184,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,pomalidomide,DB08910
,190325,DB00213,10039101,85,18810,35,13386,0.006863334,1.728242308,1.152295493,2.642258621,0.026395892,DB0021310039101_,3.634546873,0.547104885,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,190326,DB00787,10039101,104,16896,64,17184,0.00147641,1.65266403,1.198074001,2.294803487,0.007589214,DB0078710039101_,4.881027193,0.50238855,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,190327,DB08910,10039101,60,16684,41,17447,0.036432629,1.530311045,1.011190858,2.336562363,0.098440753,DB0891010039101_,2.318300407,0.425471012,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,190329,DB00787,10040753,231,16769,100,17148,9.92972815024379e-14,2.362245088,1.858271835,3.020654267,5.08282189735459e-12,DB0078710040753_,26.00515452,0.859612475,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,acyclovir,DB00787
,190330,DB08910,10040753,185,16559,108,17380,9.70556292130689e-07,1.797847817,1.409024173,2.303439642,1.39366687455095e-05,DB0891010040753_,11.18098715,0.586590292,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,190331,DB06724,10047942,185,7744,82,3837,0.430246992,1.117835966,0.854733268,1.472517357,0.598710476,DB0672410047942_,0.512977144,0.111394643,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,calcium carbonate,DB06724
,190334,DB06724,10062355,54,7875,27,3892,1,0.988441054,0.610740025,1.634817642,1,DB0672410062355_,0,-0.01162627,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,190340,DB00264,10052140,42,29565,15,24877,0.003230958,2.355915829,1.279639574,4.574595052,0.014368622,DB0026410052140_,4.242708448,0.856929539,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,metoprolol,DB00264
,190354,DB00230,10053156,69,19605,17,8634,0.03409407,1.787464771,1.039064853,3.244585497,0.093589122,DB0023010053156_,2.368841115,0.580798287,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,190357,DB01373,10053156,55,22665,8,7373,0.027607129,2.236269364,1.058491362,5.439676057,0.07937578,DB0137310053156_,2.533561998,0.804809015,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,190360,DB00484,10041349,39,2468,24,1756,0.608795679,1.156131866,0.675237426,2.01766152,0.751364921,DB0048410041349_,0.285863831,0.145079835,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,brimonidine,DB00484
,190366,DB08910,10013952,70,16674,40,17448,0.002138421,1.831188795,1.223701071,2.773944203,0.010278577,DB0891010013952_,4.577693475,0.604965371,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,190367,DB14500,10013952,43,7766,8,4065,0.00452544,2.813262731,1.305889311,6.934987078,0.018857197,DB1450010013952_,3.970860637,1.034344924,female,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,190368,DB00281,10029366,40,11418,22,5649,0.686665157,0.899546018,0.521351706,1.590766255,0.811008477,DB0028110029366_,0.209476773,-0.105865068,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,lidocaine,DB00281
,190370,DB08910,10017577,118,16626,89,17399,0.021243852,1.387465517,1.04387187,1.849594318,0.064861732,DB0891010017577_,2.73549747,0.327478714,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,190372,DB08910,10013946,70,16674,45,17443,0.011424961,1.627262486,1.102523172,2.42335748,0.039605023,DB0891010013946_,3.228799314,0.486899146,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,190375,DB08910,10056819,52,16692,46,17442,0.420109125,1.181219799,0.778564857,1.797318677,0.589031223,DB0891010056819_,0.529276087,0.166547632,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,190381,DB00868,10030124,43,2941,31,1615,0.270977416,0.761767474,0.4669103,1.255819906,0.433685961,DB0086810030124_,0.835434598,-0.272113922,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,benzonatate,DB00868
,190386,DB00451,10051608,74,47197,6,15413,0.000127311,4.027694296,1.764618721,11.33007102,0.000980334,DB0045110051608_,6.927617429,1.393194077,female,10051608,Platelet count increased,10022891,Investigations,Inv,levothyroxine,DB00451
,190402,DB08910,10015150,98,16646,47,17441,5.86433377707357e-06,2.184652007,1.526767958,3.16491479,6.79273512457261e-05,DB0891010015150_,9.597071788,0.781456551,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,pomalidomide,DB08910
,190420,DB00281,10001760,78,11380,9,5662,1.00833229798073e-06,4.311209271,2.156410735,9.788505437,1.44239534434958e-05,DB0028110001760_,11.1466203,1.461218438,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,lidocaine,DB00281
,190421,DB08910,10001760,184,16560,32,17456,7.68859121366033e-29,6.060651834,4.144353684,9.127295082,1.57886421914892e-26,DB0891010001760_,59.41050668,1.801817358,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,pomalidomide,DB08910
,190422,DB00399,10037884,47,6945,33,4965,1,1.018194393,0.637621746,1.643049055,1,DB0039910037884_,0,0.018030855,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,zoledronic acid,DB00399
,190425,DB00338,10062244,103,33571,49,22223,0.056725085,1.391479906,0.980599582,1.998216328,0.137317639,DB0033810062244_,1.985458506,0.330367861,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,190427,DB08910,10062244,39,16705,36,17452,0.644288966,1.131772065,0.700493232,1.833215765,0.780474911,DB0891010062244_,0.247852684,0.123784604,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,190430,DB00338,10066274,32,33642,32,22240,0.098296304,0.661101351,0.392012111,1.114835081,0.208305587,DB0033810066274_,1.568749111,-0.41384812,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,omeprazole,DB00338
,190431,DB00399,10066274,31,6961,19,4979,0.667444387,1.166980226,0.637943769,2.189109363,0.798024733,DB0039910066274_,0.225615689,0.154419409,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,zoledronic acid,DB00399
,190433,DB08910,10066274,34,16710,36,17452,1,0.98638121,0.59844132,1.622608245,1,DB0891010066274_,0,-0.013712376,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,pomalidomide,DB08910
,190460,DB00787,10042682,108,16892,65,17183,0.000766218,1.6901251,1.230194696,2.337509486,0.004412802,DB0078710042682_,5.423245402,0.52480255,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,190462,DB08910,10000087,82,16662,67,17421,0.139861032,1.279618571,0.914617987,1.795776291,0.2696382,DB0891010000087_,1.310674217,0.246562042,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,190470,DB01156,10005483,36,13586,23,6305,0.261991852,0.726380797,0.418435711,1.285102334,0.42369346,DB0115610005483_,0.858745057,-0.319680887,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,bupropion,DB01156
,190473,DB00484,10020751,122,2385,47,1733,0.000228396,1.885858201,1.328317247,2.715618345,0.001610932,DB0048410020751_,6.430942137,0.634382996,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,brimonidine,DB00484
,190480,DB00904,10007636,40,23029,22,14434,0.695969367,1.139615303,0.660897358,2.014121823,0.817040153,DB0090410007636_,0.202067039,0.130690752,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,ondansetron,DB00904
,190487,DB09035,10051398,438,4288,613,6077,0.869494402,1.012625372,0.888155586,1.153857427,0.941955255,DB0903510051398_,0.059797505,0.012546336,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,nivolumab,DB09035
,190490,DB09038,10036018,20,2228,94,2447,5.20203906229112e-11,0.233749443,0.136110987,0.383266597,1.77578697080938e-09,DB0903810036018_,20.14902215,-1.453505495,male,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,empagliflozin,DB09038
,190492,DB00678,10017533,44,15555,10,10714,0.000732204,3.030497259,1.50178568,6.756849317,0.004246009,DB0067810017533_,5.461775886,1.108726718,female,10017533,Fungal infection,10021881,Infections and infestations,Infec,losartan,DB00678
,190493,DB09038,10046571,86,2162,72,2469,0.062067429,1.363955011,0.980114727,1.902747822,0.147308566,DB0903810046571_,1.915225804,0.310388575,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,empagliflozin,DB09038
,190504,DB00695,10040753,388,27661,73,20455,2.29382982935024e-34,3.930299608,3.051726757,5.122862626,6.77453000724393e-32,DB0069510040753_,71.76955298,1.368715659,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,furosemide,DB00695
,190508,DB01240,10042682,72,5679,11,1565,0.079472891,1.803607615,0.947444474,3.782449531,0.177540789,DB0124010042682_,1.728554897,0.58978889,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,190526,DB00007,10074902,14,1933,41,4411,0.465110863,0.77924991,0.391354974,1.463284525,0.631951671,DB0000710074902_,0.458942357,-0.249423475,NA,10074902,Expired product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,leuprolide,DB00007
,190530,DB00956,10022086,83,5731,25,3442,0.001840615,1.993833306,1.258888339,3.261872532,0.009086752,DB0095610022086_,4.700937769,0.69005907,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,hydrocodone,DB00956
,190538,DB08889,10051055,33,3132,63,3822,0.038874482,0.639248874,0.405169576,0.992015843,0.103381944,DB0888910051055_,2.269324952,-0.447461427,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,carfilzomib,DB08889
,190539,DB08910,10051055,112,16632,186,17302,9.09230045189074e-05,0.626419032,0.490522754,0.796939665,0.00073547,DB0891010051055_,7.215000218,-0.467735752,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,pomalidomide,DB08910
,190559,DB01306,10028735,43,4165,7,3859,5.56300487527058e-07,5.690484359,2.534016336,15.01674675,8.53362025949735e-06,DB0130610028735_,11.67149687,1.738795369,female,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin aspart,DB01306
,190564,DB01234,10039101,163,31462,114,32774,0.001117173,1.489431406,1.1646317,1.910064468,0.006034089,DB0123410039101_,5.110330415,0.39839444,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,190572,DB00794,10013573,36,800,25,584,0.895209729,1.051172543,0.606271635,1.848505771,0.956081007,DB0079410013573_,0.044912634,0.049906249,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,primidone,DB00794
,190588,DB00007,10028334,19,1928,32,4420,0.287614698,1.361146197,0.726979726,2.482515305,0.452569807,DB0000710028334_,0.792813259,0.308327136,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,leuprolide,DB00007
,190592,DB00682,10048908,69,19390,26,16338,0.000280543,2.236025812,1.404950751,3.660138177,0.001911748,DB0068210048908_,6.259737024,0.804700099,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,warfarin,DB00682
,190593,DB01234,10048908,133,31492,98,32790,0.010026581,1.413065016,1.079834233,1.85436645,0.035643587,DB0123410048908_,3.334186045,0.345761116,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,dexamethasone,DB01234
,190594,DB08910,10048908,45,16699,30,17458,0.063845615,1.568146402,0.965934298,2.579390573,0.150388206,DB0891010048908_,1.89453529,0.449894286,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,pomalidomide,DB08910
,190605,DB01020,10016256,98,1715,93,1785,0.552679217,1.096742434,0.810699462,1.484622377,0.706454311,DB0102010016256_,0.347496749,0.092344363,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,isosorbide mononitrate,DB01020
,190611,DB00007,10020937,31,1916,24,4428,8.40867419921098e-05,2.984547802,1.690369529,5.329737479,0.00068805,DB0000710020937_,7.28164848,1.093448245,female,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,leuprolide,DB00007
,190614,DB01005,10019211,63,1032,24,843,0.001303954,2.14342844,1.307163498,3.620297085,0.006847356,DB0100510019211_,4.983892686,0.762406622,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,hydroxyurea,DB01005
,190618,DB00316,10062501,32,65442,30,36923,0.047523929,0.601796928,0.354098043,1.025406452,0.120448026,DB0031610062501_,2.116536937,-0.507835219,NA,10062501,Non-cardiac chest pain,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,190646,DB01413,10007515,22,1198,40,1619,0.299797529,0.743355721,0.418381666,1.288945851,0.465827922,DB0141310007515_,0.763938979,-0.296580586,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,cefepime,DB01413
,190649,DB08910,10037437,35,16709,45,17443,0.37222664,0.81195048,0.50641235,1.292244006,0.541868477,DB0891010037437_,0.612731969,-0.208315926,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,190660,DB00512,10009887,49,4688,34,5064,0.047702175,1.556683563,0.982913651,2.491453295,0.120765873,DB0051210009887_,2.113901544,0.442557637,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,vancomycin,DB00512
,190663,DB01413,10047700,46,1174,33,1626,0.005278068,1.930126171,1.199411366,3.136775077,0.021355192,DB0141310047700_,3.846460373,0.657585374,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,cefepime,DB01413
,190712,DB00497,10013082,40,19227,25,16350,0.262494018,1.360572691,0.805029262,2.341164796,0.424280855,DB0049710013082_,0.85735965,0.307905707,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,190715,DB00695,10013082,56,27993,34,20494,0.454878807,1.205821681,0.773416708,1.905262396,0.622442055,DB0069510013082_,0.474104739,0.187161227,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,190719,DB00996,10013082,83,38870,38,22387,0.25779077,1.258011458,0.846830344,1.899306644,0.418661926,DB0099610013082_,0.870691543,0.229532266,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,190728,DB00425,10013786,55,12640,28,7456,0.570426911,1.15870076,0.72167439,1.898829102,0.720960612,DB0042510013786_,0.327170772,0.147299343,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,zolpidem,DB00425
,190733,DB01015,10013786,52,9835,30,9351,0.034812777,1.647982766,1.030922298,2.678228077,0.09505807,DB0101510013786_,2.353267315,0.499551974,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,190735,DB01068,10013786,38,13725,19,6821,1,0.993951734,0.558501594,1.826767448,1,DB0106810013786_,0,-0.00606663,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,clonazepam,DB01068
,190738,DB14500,10013786,46,7763,17,4056,0.234385143,1.413726271,0.793952736,2.633945086,0.391286979,DB1450010013786_,0.938314027,0.346228964,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,potassium,DB14500
,190739,DB00230,10013990,58,19616,29,8622,0.561668195,0.879090729,0.553256191,1.425193732,0.714028786,DB0023010013990_,0.336832001,-0.128867168,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,pregabalin,DB00230
,190748,DB00959,10017577,118,7960,58,4944,0.159923742,1.263584868,0.913240368,1.765273855,0.297357589,DB0095910017577_,1.21281986,0.233952815,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,190754,DB00295,10020568,38,14625,36,9566,0.121762884,0.690451584,0.425697936,1.121762707,0.243945009,DB0029510020568_,1.410812452,-0.370409427,NA,10020568,Hyperaesthesia,10029205,Nervous system disorders,Nerv,morphine,DB00295
,190755,DB00327,10020568,47,6091,33,4229,1,0.98885478,0.61909803,1.596106686,1,DB0032710020568_,0,-0.011207793,NA,10020568,Hyperaesthesia,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,190756,DB00497,10020568,42,19225,37,16338,0.910264329,0.964660707,0.60488875,1.544132138,0.959579421,DB0049710020568_,0.041260194,-0.035978838,NA,10020568,Hyperaesthesia,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,190815,DB01039,10022437,59,2914,54,2997,0.569447574,1.12369072,0.760702353,1.66279154,0.720292901,DB0103910022437_,0.328097343,0.116618554,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,fenofibrate,DB01039
,190843,DB01039,10028334,56,2917,47,3004,0.321290539,1.226981562,0.814788198,1.85489162,0.48958647,DB0103910028334_,0.714194182,0.204557139,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,fenofibrate,DB01039
,190846,DB00327,10028411,59,6079,23,4239,0.017659804,1.788674848,1.085988457,3.040212669,0.056047808,DB0032710028411_,2.881550244,0.581475037,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydromorphone,DB00327
,190893,DB01068,10033645,36,13727,18,6822,1,0.993952616,0.549398878,1.860693507,1,DB0106810033645_,0,-0.006065744,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,190898,DB00425,10036018,38,12657,13,7471,0.109425969,1.725349438,0.898325527,3.532084739,0.225227015,DB0042510036018_,1.490646432,0.545429603,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,zolpidem,DB00425
,190899,DB00497,10036018,41,19226,33,16342,0.907161607,1.05606651,0.65115432,1.724704855,0.958621165,DB0049710036018_,0.042259314,0.054551167,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,oxycodone,DB00497
,190909,DB01068,10036018,47,13716,20,6820,0.605414962,1.168467237,0.678399154,2.083579625,0.748526504,DB0106810036018_,0.289648667,0.155692836,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,clonazepam,DB01068
,190914,DB00327,10047899,58,6080,32,4230,0.333015695,1.260971173,0.803761949,2.010537852,0.502025554,DB0032710047899_,0.689104257,0.231882196,NA,10047899,Weight increased,10022891,Investigations,Inv,hydromorphone,DB00327
,190915,DB00567,10047899,59,4460,21,2060,0.334808484,1.297577042,0.774381485,2.254983795,0.503974471,DB0056710047899_,0.685229665,0.260498712,NA,10047899,Weight increased,10022891,Investigations,Inv,cephalexin,DB00567
,190921,DB00695,10048439,77,27972,10,20518,5.55802265979045e-10,5.647933314,2.910661963,12.24794301,1.62055047823175e-08,DB0069510048439_,17.93791485,1.731289693,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,190925,DB01611,10048439,79,11834,7,2354,0.040005664,2.244853792,1.038294896,5.772743134,0.105688616,DB0161110048439_,2.247258091,0.808640393,NA,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,190980,DB00230,10062060,39,19635,11,8640,0.22024815,1.560091256,0.783129751,3.379020032,0.373774615,DB0023010062060_,0.984102298,0.444744317,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,pregabalin,DB00230
,190985,DB00695,10062060,46,28003,34,20494,1,0.990148894,0.621638751,1.591299577,1,DB0069510062060_,0,-0.00989995,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,191061,DB08906,10003988,39,2154,15,1143,0.316161489,1.379540139,0.739752702,2.70604582,0.483835295,DB0890610003988_,0.726010729,0.321750211,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone furoate,DB08906
,191064,DB00737,10011224,68,2733,13,919,0.068626363,1.758754546,0.957326678,3.487285103,0.158824034,DB0073710011224_,1.839958397,0.564605914,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,meclizine,DB00737
,191066,DB00287,10013968,37,1364,15,802,0.247501511,1.450111626,0.771146305,2.862888555,0.406729859,DB0028710013968_,0.899606051,0.371640537,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,travoprost,DB00287
,191068,DB00230,10013971,41,19633,16,8635,0.774239736,1.127031837,0.6184876,2.152728547,0.876844133,DB0023010013971_,0.13142603,0.119587484,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,191070,DB00497,10013971,55,19212,37,16338,0.295583208,1.264107382,0.817876922,1.973776453,0.461434529,DB0049710013971_,0.7734151,0.234366246,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,191078,DB00727,10017577,50,3793,46,4127,0.472103134,1.182643846,0.774410152,1.809702423,0.638154374,DB0072710017577_,0.44917506,0.16775248,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,191079,DB00737,10017577,84,2717,18,914,0.103509185,1.569631623,0.929260737,2.791662826,0.216292149,DB0073710017577_,1.531125246,0.450840957,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,meclizine,DB00737
,191137,DB00654,10052140,57,3759,22,2576,0.021120621,1.775367624,1.065347397,3.058234407,0.06454171,DB0065410052140_,2.7404436,0.574007514,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,latanoprost,DB00654
,191187,DB00334,10042458,49,2800,43,2769,0.60015171,1.126894277,0.730168561,1.744815982,0.744646664,DB0033410042458_,0.29484545,0.119465422,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,191203,DB00115,10028245,100,18325,23,10449,2.8941126552976e-05,2.479079962,1.562191693,4.091667573,0.000274925,DB0011510028245_,8.199012177,0.907887508,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,191205,DB00697,10028245,70,6026,23,1783,0.709234463,0.900516213,0.553368304,1.516403133,0.826468108,DB0069710028245_,0.19059395,-0.10478711,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,191250,DB00695,10001946,30,28019,29,20499,0.293801816,0.756851279,0.438793996,1.307298109,0.459547227,DB0069510001946_,0.777513564,-0.278588506,NA,10001946,Ammonia increased,10022891,Investigations,Inv,furosemide,DB00695
,191257,DB00338,10005619,50,33624,20,22252,0.066149573,1.654456557,0.967038665,2.934886089,0.1544244,DB0033810005619_,1.868050623,0.503472591,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,omeprazole,DB00338
,191259,DB00451,10005619,68,47203,13,15406,0.092100242,1.707127813,0.934398217,3.369940235,0.198593508,DB0045110005619_,1.616495219,0.534812317,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,191263,DB00695,10005619,65,27984,18,20510,0.000125794,2.646570606,1.55027997,4.742837535,0.000970929,DB0069510005619_,6.9372577,0.973264691,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,furosemide,DB00695
,191322,DB00497,10017412,55,19212,39,16336,0.408443635,1.199136836,0.780798904,1.857487804,0.577839818,DB0049710017412_,0.54845858,0.181601994,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,oxycodone,DB00497
,191359,DB01060,10012378,104,8483,43,5038,0.048370126,1.436357548,0.995759217,2.103708181,0.122027906,DB0106010012378_,2.10350552,0.362110428,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,amoxicillin,DB01060
,191367,DB00003,10053762,38,2960,31,2562,0.903445951,1.060991553,0.640801091,1.769041217,0.957389002,DB0000310053762_,0.043545489,0.059203898,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,dornase alfa,DB00003
,191368,DB00684,10053762,114,2678,79,2269,0.185407045,1.222600171,0.904358928,1.659582606,0.330695538,DB0068410053762_,1.106557152,0.200979878,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tobramycin,DB00684
,191374,DB01276,10016256,40,1977,23,1488,0.368697976,1.308867422,0.761091736,2.300864928,0.538354163,DB0127610016256_,0.61923864,0.2691622,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,191427,DB00879,10033371,17,1760,44,3668,0.494053932,0.80526817,0.430046444,1.442965486,0.656714839,DB0087910033371_,0.420505389,-0.216579926,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,emtricitabine,DB00879
,191494,DB00635,10029202,32,33021,25,23769,0.789040142,0.921364715,0.528892825,1.622157383,0.885694655,DB0063510029202_,0.121383021,-0.081899322,NA,10029202,Nervous system disorder,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,191500,DB00115,10029223,64,18361,27,10445,0.229367399,1.348416308,0.846990221,2.20118909,0.3851362,DB0011510029223_,0.954158241,0.298930799,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,191531,DB00115,10050296,47,18378,15,10457,0.048128718,1.782818924,0.978909241,3.434487923,0.121582253,DB0011510050296_,2.107164263,0.578195777,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,191539,DB00318,10061355,8,4275,48,1791,5.11429059452648e-18,0.069838416,0.028511362,0.149357947,4.43660489363461e-16,DB0031810061355_,35.35147207,-2.661571049,male,10061355,Poisoning,10022117,"Injury, poisoning and procedural complications",Inj&P,codeine,DB00318
,191587,DB00115,10070863,42,18383,27,10445,0.617785087,0.883855514,0.531996879,1.491662939,0.75875434,DB0011510070863_,0.276077217,-0.123461675,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,191588,DB00422,10070863,73,3362,67,2882,0.731927279,0.934022863,0.658521403,1.326499502,0.8442103,DB0042210070863_,0.169353645,-0.068254363,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,methylphenidate,DB00422
,191592,DB00318,10074903,16,4267,40,1799,1.71140357511465e-10,0.168711676,0.087952723,0.309014416,5.38733448765132e-09,DB0031810074903_,19.0392151,-1.779564082,male,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,codeine,DB00318
,191594,DB00924,10074903,81,10081,32,4219,0.836424365,1.059348994,0.694340451,1.651653159,0.915542875,DB0092410074903_,0.088238083,0.057654563,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,191595,DB00956,10074903,77,5737,36,3431,0.241310119,1.27912726,0.848355407,1.96115801,0.399427795,DB0095610074903_,0.917722269,0.246178017,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocodone,DB00956
,191599,DB08931,10018627,42,6535,24,2422,0.095816201,0.64861867,0.382875892,1.122366028,0.204492437,DB0893110018627_,1.587224287,-0.4329103,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,riociguat,DB08931
,191601,DB06273,10007882,40,5055,14,1396,0.411879196,0.789065686,0.418832547,1.574909957,0.581328475,DB0627310007882_,0.54243932,-0.236905709,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,tocilizumab,DB06273
,191665,DB00814,10000060,45,8242,19,3396,0.891283747,0.975875866,0.558365511,1.769393555,0.954816394,DB0081410000060_,0.046236214,-0.024419887,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,191679,DB01394,10017577,42,1398,23,1980,0.00020287,2.585593606,1.511886754,4.52586043,0.001458346,DB0139410017577_,6.530452316,0.949955116,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,colchicine,DB01394
,191683,DB01190,10022437,45,4889,17,2268,0.583443251,1.227909184,0.687358546,2.293812605,0.731448741,DB0119010022437_,0.312728135,0.205312873,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,clindamycin,DB01190
,191685,DB00620,10023232,47,4781,15,3117,0.013244964,2.042622279,1.119903462,3.939908766,0.044533914,DB0062010023232_,3.11150427,0.714234413,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,triamcinolone,DB00620
,191688,DB01394,10023232,30,1410,20,1983,0.013261483,2.109134575,1.153470876,3.935658896,0.044569504,DB0139410023232_,3.110705429,0.74627771,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,colchicine,DB01394
,191714,DB00230,10048948,48,19626,9,8642,0.014106091,2.34839089,1.139012055,5.446161033,0.04687763,DB0023010048948_,3.060214694,0.853730366,NA,10048948,Bedridden,10041244,Social circumstances,SocCi,pregabalin,DB00230
,191715,DB00316,10048948,56,65418,21,36932,0.122724551,1.505471561,0.897107726,2.618141888,0.245326313,DB0031610048948_,1.405166065,0.409106179,NA,10048948,Bedridden,10041244,Social circumstances,SocCi,acetaminophen,DB00316
,191727,DB00230,10050256,113,19561,34,8617,0.058894092,1.464090665,0.989123957,2.218266022,0.141385625,DB0023010050256_,1.956264192,0.381234344,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,191731,DB01373,10050256,43,22677,14,7367,1,0.997804635,0.535099055,1.975933915,1,DB0137310050256_,0,-0.002197779,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,calcium,DB01373
,191737,DB01050,10051118,63,18045,22,9349,0.135675991,1.483611805,0.899743137,2.533977951,0.263653022,DB0105010051118_,1.333121351,0.394479524,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,191781,DB13961,10006002,48,9409,20,6394,0.082158051,1.630899142,0.948696111,2.903920536,0.181923624,DB1396110006002_,1.704168329,0.489131484,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fish oil,DB13961
,191791,DB09270,10035226,19,3095,32,2336,0.006418897,0.448204366,0.239387522,0.817515062,0.024982038,DB0927010035226_,3.689598179,-0.802505977,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ubidecarenone,DB09270
,191813,DB00620,10037377,31,4797,36,3096,0.017082689,0.555825251,0.331738308,0.926367429,0.054595232,DB0062010037377_,2.907808726,-0.58730133,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,triamcinolone,DB00620
,191881,DB01076,10013786,124,25623,99,25484,0.107446996,1.245722722,0.948229863,1.640144401,0.222337674,DB0107610013786_,1.503558,0.219715861,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,191883,DB00590,10037844,20,756,44,1908,0.674060193,1.147110905,0.636001293,2.003118651,0.802321793,DB0059010037844_,0.220245513,0.137246524,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,doxazosin,DB00590
,191899,DB01432,10019211,58,1233,12,658,0.001883316,2.578303346,1.357476411,5.313190642,0.009267615,DB0143210019211_,4.681229268,0.947131565,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cholestyramine,DB01432
,191900,DB00687,10025482,49,937,37,1048,0.078553061,1.480913718,0.937404247,2.356817557,0.175920364,DB0068710025482_,1.737723864,0.392659275,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,fludrocortisone,DB00687
,191909,DB00557,10040047,64,5923,45,3022,0.103914773,0.725636433,0.486578988,1.090237926,0.21688965,DB0055710040047_,1.528366578,-0.320706171,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,hydroxyzine,DB00557
,191957,DB05679,10040753,48,6883,19,4890,0.033882857,1.79472158,1.03395163,3.237493261,0.093148132,DB0567910040753_,2.373564234,0.584849901,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,ustekinumab,DB05679
,191981,DB01225,10016322,40,5004,32,4608,0.636108202,1.151061856,0.703708575,1.896507329,0.773818154,DB0122510016322_,0.256418376,0.140684869,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,191990,DB00316,10040808,53,65421,54,36899,0.002419693,0.553610751,0.371632595,0.824293237,0.011363808,DB0031610040808_,4.477321667,-0.591293455,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,192019,DB01068,10042772,87,13676,42,6798,0.925462104,1.029686106,0.70369623,1.527547254,0.968132107,DB0106810042772_,0.032386727,0.029254004,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,192021,DB00399,10023547,71,6921,60,4938,0.373013685,0.844301202,0.589038318,1.213662749,0.542713645,DB0039910023547_,0.611173456,-0.169245973,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,zoledronic acid,DB00399
,192027,DB01234,10060084,43,31582,41,32847,0.743600428,1.090771723,0.694176289,1.716255035,0.853423742,DB0123410060084_,0.158499088,0.086885448,NA,10060084,Light chain analysis increased,10022891,Investigations,Inv,dexamethasone,DB01234
,192037,DB01276,10053762,53,1964,30,1481,0.219434398,1.332089187,0.831016073,2.17102289,0.372803746,DB0127610053762_,0.986703147,0.286748527,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,exenatide,DB01276
,192043,DB00338,10076309,260,33414,131,22141,0.011007356,1.315129606,1.061218792,1.636298473,0.038420869,DB0033810076309_,3.259154512,0.27393522,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,192044,DB00482,10076309,77,8182,25,3046,0.654460576,1.146607411,0.720399162,1.883310494,0.788255606,DB0048210076309_,0.237932868,0.136807505,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,celecoxib,DB00482
,192045,DB00722,10076309,185,25218,128,25904,0.00064637,1.484609025,1.177865031,1.87603007,0.00383416,DB0072210076309_,5.563804782,0.395151455,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,192046,DB01098,10076309,67,8082,47,7162,0.258287457,1.263238273,0.855887991,1.877844482,0.419247587,DB0109810076309_,0.869293633,0.233678482,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,rosuvastatin,DB01098
,192094,DB08895,10029331,73,28041,21,6625,0.430609435,0.821293971,0.499330066,1.406308159,0.599102221,DB0889510029331_,0.512323042,-0.196874169,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,192134,DB00776,10033371,65,1840,25,1314,0.00889532,1.856399762,1.147048694,3.090885743,0.032416827,DB0077610033371_,3.429077636,0.618639,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,oxcarbazepine,DB00776
,192143,DB08895,10016334,72,28042,6,6640,0.008715733,2.841418681,1.2428569,8.001853386,0.031909331,DB0889510016334_,3.444856804,1.044303463,female,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,192151,DB09270,10021097,36,3078,44,2324,0.04007761,0.617823445,0.385003789,0.985603454,0.105849491,DB0927010021097_,2.245737093,-0.481552549,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ubidecarenone,DB09270
,192155,DB00188,10013700,37,7849,29,8799,0.173954802,1.430244142,0.855035595,2.41370012,0.316111996,DB0018810013700_,1.151658711,0.357845158,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,bortezomib,DB00188
,192165,DB00186,10012373,56,16845,43,9965,0.211623723,0.770440041,0.508129042,1.175344674,0.363374024,DB0018610012373_,1.012322607,-0.260793446,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,192187,DB11750,10037162,63,2437,26,1487,0.098203803,1.478367489,0.91781068,2.444301136,0.208168304,DB1175010037162_,1.569408372,0.390938431,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,clobetasol,DB11750
,192224,DB00471,10043607,114,14075,37,5428,0.412003238,1.188196199,0.812352611,1.774020606,0.581427814,DB0047110043607_,0.542268453,0.172436358,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,montelukast,DB00471
,192248,DB09072,10039906,86,6385,43,2492,0.199806094,0.780585174,0.533543315,1.156964615,0.348802397,DB0907210039906_,1.053249716,-0.247711418,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,sodium oxybate,DB09072
,192256,DB01240,10037855,52,5699,16,1560,0.657894331,0.889626067,0.498332427,1.67423955,0.790941637,DB0124010037855_,0.234531098,-0.116954054,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,epoprostenol,DB01240
,192272,DB00588,10037153,106,16418,50,8418,0.671845363,1.086981362,0.768675366,1.555143872,0.800827851,DB0058810037153_,0.222109273,0.083404461,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,192278,DB00051,10076309,46,25685,27,11393,0.254258776,0.755690415,0.459752938,1.264887868,0.414873171,DB0005110076309_,0.879782417,-0.280123491,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,192279,DB00588,10076309,140,16384,62,8406,0.370590837,1.158506142,0.852142178,1.590561334,0.540310072,DB0058810076309_,0.615612096,0.147131366,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,192289,DB00482,10041349,73,8186,28,3043,0.910531116,0.969160351,0.617658523,1.55980241,0.959635541,DB0048210041349_,0.041201712,-0.0313252,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,192303,DB00480,10041541,102,67326,90,67572,0.38673899,1.137472587,0.848098929,1.527760838,0.556827035,DB0048010041541_,0.585500617,0.128808772,NA,10041541,Spinal compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,192306,DB00065,10016825,161,9303,69,4888,0.162438312,1.225929704,0.917045019,1.653573698,0.300607193,DB0006510016825_,1.201950873,0.203699498,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,infliximab,DB00065
,192308,DB00158,10020100,56,16759,25,8079,0.812848145,1.079830458,0.662206854,1.807536303,0.899400706,DB0015810020100_,0.106026619,0.076804045,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,192311,DB00065,10020642,36,9428,44,4913,0.00020354,0.426383483,0.266272242,0.678787437,0.001462361,DB0006510020642_,6.527702688,-0.852416143,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,infliximab,DB00065
,192312,DB00065,10044565,40,9424,30,4927,0.164557488,0.697077118,0.422861557,1.160572769,0.303485447,DB0006510044565_,1.19242162,-0.360859232,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,infliximab,DB00065
,192359,DB06643,10023547,43,52378,14,7501,0.013829647,0.439864196,0.23590864,0.870993088,0.046098824,DB0664310023547_,3.076967841,-0.821289245,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,denosumab,DB06643
,192363,DB00480,10025650,45,67383,70,67592,0.024757198,0.644856722,0.433234692,0.951310353,0.072957336,DB0048010025650_,2.617880447,-0.438727123,NA,10025650,Malignant melanoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenalidomide,DB00480
,192367,DB06637,10048959,63,6099,11,2008,0.056927048,1.885385412,0.982930011,3.976397649,0.137656619,DB0663710048959_,1.982992966,0.634132263,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,192389,DB00904,10038683,36,23033,28,14428,0.440737805,0.805392554,0.477667652,1.370817652,0.609068806,DB0090410038683_,0.495824036,-0.216425476,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,192395,DB00019,10017577,60,18952,20,9509,0.12310916,1.505203581,0.893816263,2.638169959,0.245834847,DB0001910017577_,1.403095321,0.408928159,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,192399,DB01248,10033553,48,2652,14,1360,0.077459228,1.758022244,0.949227627,3.465442347,0.174048198,DB0124810033553_,1.748423018,0.564189452,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,docetaxel,DB01248
,192401,DB00814,10008469,43,8244,14,3401,0.559060853,1.267047867,0.67887757,2.510974784,0.711840552,DB0081410008469_,0.339901337,0.236689681,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,192428,DB00181,10042772,57,9799,29,5842,0.576395946,1.171831309,0.735901317,1.903069184,0.725636641,DB0018110042772_,0.320705884,0.158567746,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,192429,DB00656,10042772,77,11936,55,6564,0.144679597,0.769936672,0.536929226,1.110416811,0.276574779,DB0065610042772_,1.285274046,-0.261447012,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,192492,DB01241,10013709,31,912,42,1029,0.475227596,0.83286098,0.501626701,1.36956219,0.640861779,DB0124110013709_,0.444941479,-0.182888541,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,gemfibrozil,DB01241
,192498,DB00635,10069339,464,32589,605,23189,1.5137592178278e-22,0.545743887,0.481952796,0.617634789,1.99444416243628e-20,DB0063510069339_,45.36133646,-0.605605484,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,192499,DB00877,10069339,30,1078,54,1377,0.146735275,0.709741946,0.435179898,1.138081325,0.279376822,DB0087710069339_,1.275193792,-0.342853831,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,sirolimus,DB00877
,192500,DB01024,10069339,69,2142,119,2001,6.97926344636245e-05,0.54174429,0.394176199,0.739771203,0.000585634,DB0102410069339_,7.442815051,-0.612961178,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,mycophenolic acid,DB01024
,192523,DB00230,10076309,488,19186,154,8497,0.000224486,1.40341247,1.166279964,1.696398045,0.001587468,DB0023010076309_,6.44561505,0.338906749,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,192549,DB00437,10069339,202,6719,337,11209,1,0.999938965,0.833488468,1.197298798,1,DB0043710069339_,0,-6.10E-05,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,allopurinol,DB00437
,192551,DB00907,10013654,452,686,1008,803,3.81777962818366e-17,0.52500132,0.450149583,0.611955754,2.97775482275394e-15,DB0090710013654_,33.44760679,-0.644354502,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,cocaine,DB00907
,192559,DB01275,10010305,49,3930,36,3313,0.584594657,1.147395363,0.729113513,1.821035896,0.732355822,DB0127510010305_,0.311488787,0.137494472,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,hydralazine,DB01275
,192565,DB06228,10076309,88,15824,72,16004,0.204665209,1.236114504,0.894257495,1.713396493,0.354669371,DB0622810076309_,1.036569272,0.211972995,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,192567,DB00334,10049414,25,2824,33,2779,0.292546114,0.745545203,0.423807426,1.296299089,0.458135458,DB0033410049414_,0.780590378,-0.293639513,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,olanzapine,DB00334
,192609,DB01373,10037855,64,22656,12,7369,0.082753921,1.734601779,0.927104642,3.533205569,0.182988712,DB0137310037855_,1.698330811,0.550777865,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,192615,DB00695,10060795,97,27952,50,20478,0.044771769,1.421257873,0.999774037,2.042434329,0.115132413,DB0069510060795_,2.161672397,0.351542306,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,furosemide,DB00695
,192616,DB00814,10060795,39,8248,12,3403,0.441672789,1.340829567,0.686801148,2.816769262,0.609894929,DB0081410060795_,0.494468584,0.293288502,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,meloxicam,DB00814
,192628,DB00126,10043607,83,10088,50,5895,0.857285938,0.970014498,0.673824813,1.408929025,0.931551329,DB0012610043607_,0.070903987,-0.030444261,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,ascorbic acid,DB00126
,192629,DB01098,10043607,48,8101,53,7156,0.272614469,0.800027527,0.529180646,1.206808255,0.435544773,DB0109810043607_,0.831157679,-0.223109143,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,rosuvastatin,DB01098
,192643,DB00814,10013946,76,8211,21,3394,0.11609194,1.495921925,0.910976033,2.558472035,0.235280977,DB0081410013946_,1.446974831,0.402742689,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,192703,DB00175,10076309,73,8058,37,6069,0.053018344,1.485931419,0.985851308,2.274026004,0.130668948,DB0017510076309_,2.035088265,0.396041794,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,192704,DB00186,10076309,128,16773,61,9947,0.174152257,1.244422932,0.909404432,1.718809893,0.316350524,DB0018610076309_,1.150904427,0.218671914,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,192705,DB00331,10076309,199,24747,138,20614,0.099817314,1.201189977,0.961114951,1.504687458,0.210493651,DB0033110076309_,1.558299789,0.183312713,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,192707,DB00715,10076309,37,4806,14,2273,0.548718553,1.249871071,0.658410139,2.508007686,0.70315265,DB0071510076309_,0.352181269,0.223040403,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,paroxetine,DB00715
,192708,DB00727,10076309,32,3811,31,4142,0.704730296,1.121896784,0.66150469,1.90503987,0.822904333,DB0072710076309_,0.194915327,0.11502081,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,nitroglycerin,DB00727
,192710,DB01222,10076309,109,9165,60,5345,0.748905586,1.059475658,0.764730702,1.47992193,0.857527971,DB0122210076309_,0.153701481,0.057774124,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,budesonide,DB01222
,192715,DB00563,10013496,39,46607,21,15327,0.0726155,0.61073866,0.350438732,1.093126716,0.165858397,DB0056310013496_,1.796620888,-0.493086137,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,192716,DB00563,10019063,41,46605,16,15332,0.541568251,0.84297804,0.462786522,1.609808216,0.696945972,DB0056310019063_,0.361047387,-0.170814371,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,192720,DB00005,10029412,46,128036,15,42404,1,1.015647127,0.556810258,1.958718127,1,DB0000510029412_,0,0.015525973,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,192726,DB00423,10002855,68,2399,15,1025,0.020328869,1.936603193,1.089468974,3.665844493,0.062603889,DB0042310002855_,2.770927879,0.660935507,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,methocarbamol,DB00423
,192740,DB00559,10069339,55,9604,35,3271,0.005008011,0.535261082,0.343405918,0.844259639,0.020490917,DB0055910069339_,3.887773588,-0.625000647,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,bosentan,DB00559
,192741,DB00402,10016173,39,1313,19,677,0.889100549,1.058338498,0.591689094,1.954966819,0.953955749,DB0040210016173_,0.047137994,0.056700224,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,eszopiclone,DB00402
,192742,DB00540,10016173,76,2407,47,1044,0.072340367,0.701425841,0.477480457,1.039559907,0.165352107,DB0054010016173_,1.799678098,-0.3546401,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,nortriptyline,DB00540
,192743,DB00402,10025482,45,1307,14,682,0.095889499,1.676845727,0.896187093,3.332094042,0.204609329,DB0040210025482_,1.586652829,0.516914485,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,eszopiclone,DB00402
,192788,DB08932,10005746,43,19400,11,6586,0.530605577,1.327045861,0.672485023,2.855501738,0.687635527,DB0893210005746_,0.374496338,0.282955314,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,macitentan,DB08932
,192806,DB09037,10009887,50,2476,41,2794,0.138949303,1.376046356,0.888876906,2.140923504,0.268352861,DB0903710009887_,1.31545252,0.319214428,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,pembrolizumab,DB09037
,192813,DB01075,10017413,54,19894,35,11062,0.506833154,0.857911991,0.55012096,1.353497198,0.667507237,DB0107510017413_,0.404205047,-0.153253759,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,diphenhydramine,DB01075
,192818,DB08931,10037844,121,6456,42,2404,0.789673904,1.072762219,0.746869112,1.567588858,0.886048773,DB0893110037844_,0.120983281,0.070236835,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,riociguat,DB08931
,192843,DB00230,10056812,173,19501,34,8617,4.50836599740481e-06,2.24830891,1.547960717,3.353637275,5.40489852870174e-05,DB0023010056812_,9.825619788,0.810178338,NA,10056812,Body height decreased,10022891,Investigations,Inv,pregabalin,DB00230
,192850,DB01248,10040047,34,2666,23,1351,0.323312135,0.74919507,0.42667276,1.337745109,0.491754736,DB0124810040047_,0.709775192,-0.288755889,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,docetaxel,DB01248
,192857,DB00112,10013700,35,5898,17,4074,0.259580874,1.422068063,0.774389955,2.71077237,0.420723495,DB0011210013700_,0.865779442,0.352112195,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,bevacizumab,DB00112
,192875,DB01076,10013754,53,25694,23,25560,0.000761364,2.292438117,1.380343298,3.920172932,0.004387253,DB0107610013754_,5.429051983,0.829615931,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,192876,DB01076,10057362,62,25685,81,25502,0.111643086,0.75998503,0.536727444,1.071607719,0.228519917,DB0107610057362_,1.476131909,-0.274456543,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,192897,DB00761,10049438,49,15258,31,8594,0.641370837,0.890298937,0.555992465,1.445446418,0.77810544,DB0076110049438_,0.250893237,-0.116197989,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,192900,DB00169,10061148,61,38630,24,18151,0.487698026,1.1942283,0.733395118,2.003791848,0.651449966,DB0016910061148_,0.428554683,0.177500203,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,192905,DB00695,10061148,47,28002,25,20503,0.232452652,1.376521623,0.829891813,2.334677321,0.38890064,DB0069510061148_,0.944431392,0.319559754,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,192907,DB00904,10061148,58,23011,47,14409,0.192880837,0.772749234,0.516603607,1.161192315,0.340248502,DB0090410061148_,1.07807904,-0.25780069,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,192908,DB00169,10069339,358,38333,310,17865,5.23062521760325e-15,0.538190115,0.46052856,0.629318667,3.19737171731864e-13,DB0016910069339_,28.77127707,-0.619543408,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,192909,DB00213,10069339,627,18268,574,12847,8.54393717812624e-06,0.768201405,0.683288549,0.863762482,9.46385961765901e-05,DB0021310069339_,9.265445172,-0.263703335,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,192910,DB00332,10069339,38,2646,39,1617,0.024704185,0.595539892,0.369046131,0.960181979,0.072854202,DB0033210069339_,2.619295071,-0.518286904,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ipratropium,DB00332
,192911,DB00364,10069339,44,2706,35,1365,0.053982479,0.634202381,0.395561921,1.023686212,0.132453263,DB0036410069339_,2.021525427,-0.455387163,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,sucralfate,DB00364
,192913,DB00421,10069339,267,8636,272,4980,1.52130913657719e-10,0.566106851,0.474595069,0.67520109,4.81608023050291e-09,DB0042110069339_,19.15130547,-0.568972435,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,spironolactone,DB00421
,192914,DB00761,10069339,375,14932,263,8362,0.006554352,0.798508466,0.678616338,0.940635945,0.025410199,DB0076110069339_,3.672604632,-0.225009709,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,potassium chloride,DB00761
,192961,DB06643,10069339,48,52373,40,7475,2.82839009844091e-14,0.171279701,0.110132749,0.26762184,1.5634959776555e-12,DB0664310069339_,27.18409679,-1.764457381,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,denosumab,DB06643
,192962,DB06643,10049470,188,52233,12,7503,0.00363467,2.25041611,1.257488474,4.435517693,0.015793899,DB0664310049470_,4.148131562,0.811115137,NA,10049470,Bone density decreased,10022891,Investigations,Inv,denosumab,DB06643
,192963,DB08889,10061428,36,3129,51,3834,0.517783565,0.864946585,0.546849922,1.355274917,0.677293064,DB0888910061428_,0.389651214,-0.145087526,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,carfilzomib,DB08889
,192964,DB00422,10039906,50,3385,44,2905,0.917334513,0.975222138,0.63519074,1.50193779,0.963310269,DB0042210039906_,0.037379729,-0.025090001,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,methylphenidate,DB00422
,193006,DB00295,10020751,150,14513,42,9560,2.34323474961943e-07,2.352484823,1.659227847,3.399849522,3.91557059082942e-06,DB0029510020751_,12.45054949,0.855472141,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,morphine,DB00295
,193008,DB06228,10040070,37,15875,61,16015,0.0196603,0.61191934,0.395121854,0.93616796,0.06098672,DB0622810040070_,2.797099142,-0.491154803,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,193051,DB00843,10037660,24,2170,30,2143,0.413911569,0.790090579,0.440457745,1.403021427,0.583250628,DB0084310037660_,0.539138291,-0.235607683,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,donepezil,DB00843
,193060,DB00695,10029366,45,28004,38,20490,0.578444945,0.866469429,0.549856797,1.371890103,0.727188722,DB0069510029366_,0.318569245,-0.143328452,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,furosemide,DB00695
,193073,DB00620,10029331,50,4778,34,3098,0.823349518,0.953539213,0.603028225,1.524126045,0.906247631,DB0062010029331_,0.098442687,-0.04757473,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,triamcinolone,DB00620
,193075,DB01050,10029331,149,17959,88,9283,0.335516282,0.875215151,0.667158616,1.153870159,0.50470973,DB0105010029331_,0.683771807,-0.133285536,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,193102,DB01039,10006451,46,2927,28,3023,0.034544249,1.696580825,1.035035491,2.826914045,0.094518876,DB0103910006451_,2.358955724,0.528614946,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,fenofibrate,DB01039
,193105,DB00471,10020642,99,14090,31,5434,0.376534517,1.23161036,0.814373824,1.910446494,0.546394234,DB0047110020642_,0.604414524,0.208322549,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,193107,DB01039,10020642,31,2942,20,3031,0.121451715,1.596756528,0.879319761,2.963159537,0.243514881,DB0103910020642_,1.412577224,0.467974402,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,fenofibrate,DB01039
,193109,DB00231,10028810,47,3249,17,2122,0.039057067,1.805510989,1.014478258,3.363442031,0.103759912,DB0023110028810_,2.265675588,0.590843648,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,temazepam,DB00231
,193122,DB00836,10009887,44,5491,48,4027,0.070967448,0.672307203,0.435286005,1.036052243,0.162993522,DB0083610009887_,1.814044818,-0.397039895,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,193123,DB01050,10009887,52,18056,36,9335,0.178198066,0.746817481,0.478568271,1.176812689,0.321566398,DB0105010009887_,1.13455123,-0.291934459,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,193134,DB00514,10070863,253,1913,232,1304,0.002554915,0.743426405,0.61099808,0.904776864,0.011862912,DB0051410070863_,4.434338363,-0.296485502,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,dextromethorphan,DB00514
,193135,DB00669,10070863,53,6324,11,1086,0.593179017,0.827444223,0.425440747,1.762585662,0.739293122,DB0066910070863_,0.302060789,-0.189413578,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,sumatriptan,DB00669
,193148,DB00863,10038695,67,10606,66,5774,0.000719829,0.552648903,0.386863006,0.789754459,0.004190631,DB0086310038695_,5.474903908,-0.593032375,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,193155,DB00661,10025482,101,3427,24,1571,0.003197936,1.928961734,1.220613067,3.161897325,0.014254325,DB0066110025482_,4.250694903,0.656981896,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,verapamil,DB00661
,193183,DB06404,10076309,64,3005,25,875,0.248275601,0.745483873,0.459676353,1.243411963,0.407640963,DB0640410076309_,0.897368484,-0.293721778,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,human c1-esterase inhibitor,DB06404
,193191,DB05676,10003285,231,46898,104,25225,0.135749981,1.194661738,0.943331351,1.521554312,0.263724187,DB0567610003285_,1.332851467,0.177863081,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,193192,DB00950,10002855,84,4634,23,2033,0.044375274,1.602158399,0.996795308,2.671451304,0.11435334,DB0095010002855_,2.168462153,0.471351719,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,fexofenadine,DB00950
,193194,DB01175,10012374,36,10688,21,4871,0.39132595,0.781319735,0.443432323,1.410132927,0.561226577,DB0117510012374_,0.577630575,-0.246770821,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,193225,DB00758,10005555,28,8272,32,10042,0.896779581,1.062197233,0.615668282,1.822996547,0.95631736,DB0075810005555_,0.044665454,0.060339624,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,clopidogrel,DB00758
,193227,DB08868,10037844,145,9057,34,2477,0.46348703,1.166338622,0.795849411,1.752976651,0.630675393,DB0886810037844_,0.460963981,0.153869459,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,fingolimod,DB08868
,193245,DB00355,10025127,44,1749,47,1216,0.051245686,0.650985823,0.418631619,1.010638915,0.127375211,DB0035510025127_,2.060618133,-0.429267414,NA,10025127,Lung transplant,10042613,Surgical and medical procedures,Surg,aztreonam,DB00355
,193251,DB00186,10003445,63,16838,34,9974,0.752381263,1.097600249,0.711641389,1.719467054,0.86045822,DB0018610003445_,0.150290218,0.093126205,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,193288,DB00853,10019211,40,1781,65,2201,0.196283694,0.760557205,0.497112126,1.151121863,0.344563188,DB0085310019211_,1.065477787,-0.27370395,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,temozolomide,DB00853
,193289,DB00773,10020772,33,2290,51,2776,0.320033433,0.784419528,0.488554394,1.244024646,0.488210397,DB0077310020772_,0.717008826,-0.24281129,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,etoposide,DB00773
,193316,DB01234,10018388,38,31587,15,32873,0.001331264,2.636497368,1.416508774,5.159668408,0.006967798,DB0123410018388_,4.966456054,0.969451282,NA,10018388,Glossodynia,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,193322,DB01075,10031009,44,19904,21,11076,0.606408536,1.165914762,0.678216361,2.065431932,0.749333538,DB0107510031009_,0.288571083,0.153505982,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,193327,DB01234,10040752,32,31593,38,32850,0.63301929,0.875612643,0.529406729,1.439777207,0.771750551,DB0123410040752_,0.259093901,-0.132831475,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,dexamethasone,DB01234
,193336,DB01590,10068319,30,4708,27,2840,0.133489944,0.670314462,0.3842407,1.174505782,0.260636467,DB0159010068319_,1.344628688,-0.400008331,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,everolimus,DB01590
,193342,DB00787,10044034,99,16901,105,17143,0.778990985,0.956345908,0.718689579,1.271839345,0.879581513,DB0078710044034_,0.128309038,-0.044635603,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,193364,DB01136,10025082,31,9853,28,11087,0.434493103,1.245785381,0.722451076,2.157163622,0.60302719,DB0113610025082_,0.505792993,0.219766159,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,193371,DB00115,10022687,57,18368,29,10443,0.655081545,1.117492814,0.702190675,1.813881834,0.788793665,DB0011510022687_,0.237250507,0.111087617,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,193373,DB00051,10037867,51,25680,19,11401,0.604386365,1.191675338,0.69117682,2.138420511,0.747783925,DB0005110037867_,0.290641213,0.175360164,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,193381,DB00295,10060800,39,14624,22,9580,0.602911203,1.161243483,0.671240844,2.057610363,0.746678937,DB0029510060800_,0.292119989,0.149491399,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,morphine,DB00295
,193387,DB00734,10014387,36,4014,36,4866,0.475971082,1.212226767,0.740672629,1.983934537,0.641432955,DB0073410014387_,0.444050613,0.192458971,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,risperidone,DB00734
,193396,DB00169,10042361,28,38663,34,18141,0.000198019,0.3864125,0.225644383,0.656761877,0.001428747,DB0016910042361_,6.550957591,-0.950849827,NA,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,193397,DB00451,10042361,39,47232,39,15380,1.93343263863143e-06,0.325647716,0.203369136,0.521308327,2.57088887345688e-05,DB0045110042361_,10.56867376,-1.121939107,male,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,193398,DB00641,10042361,21,14103,46,12429,0.000499952,0.402345358,0.227934724,0.688444803,0.003091692,DB0064110042361_,5.779036793,-0.91044446,NA,10042361,Subdural haematoma,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,193409,DB00641,10069339,255,13869,337,12138,8.33124901547169e-07,0.662252066,0.559546346,0.78302532,1.2206626553605e-05,DB0064110069339_,11.31353159,-0.412109031,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,simvastatin,DB00641
,193411,DB01039,10069339,43,2930,75,2976,0.005120474,0.582389148,0.389271418,0.861709361,0.020855609,DB0103910069339_,3.870132366,-0.540616415,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,fenofibrate,DB01039
,193413,DB01050,10043417,60,18048,18,9353,0.041865968,1.727398944,1.005374294,3.110939059,0.109453648,DB0105010043417_,2.212254121,0.546616777,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,193418,DB01060,10076309,45,8542,28,5053,0.903439806,0.950712875,0.579482273,1.584730294,0.957389002,DB0106010076309_,0.043545489,-0.050543181,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,amoxicillin,DB01060
,193437,DB05679,10013968,95,6836,57,4852,0.362111905,1.182917802,0.841110894,1.67651384,0.531767775,DB0567910013968_,0.631548397,0.1679841,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ustekinumab,DB05679
,193440,DB05679,10048959,58,6873,26,4883,0.058328241,1.584813653,0.980287125,2.626847956,0.140347657,DB0567910048959_,1.963632673,0.460466831,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,193473,DB01062,10061818,36,4450,15,1730,0.875625205,0.933039375,0.496748805,1.839169209,0.946548848,DB0106210061818_,0.054932701,-0.069307876,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,193489,DB00222,10069339,62,3144,83,3045,0.064230438,0.723506733,0.510027193,1.021719232,0.151057761,DB0022210069339_,1.890092989,-0.323645427,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,glimepiride,DB00222
,193490,DB00524,10069339,103,1474,122,1222,0.012063161,0.700018606,0.527230873,0.928028062,0.041310688,DB0052410069339_,3.186634022,-0.356648364,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,metolazone,DB00524
,193491,DB00715,10069339,66,4777,20,2267,0.081864642,1.565976318,0.934770242,2.734261952,0.18148797,DB0071510069339_,1.706565911,0.448509475,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,paroxetine,DB00715
,193492,DB00887,10069339,103,2238,137,1678,2.17679055989202e-05,0.563791877,0.428820666,0.739410608,0.000214738,DB0088710069339_,8.446091882,-0.573070107,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,bumetanide,DB00887
,193500,DB00658,10020711,24,1279,45,1351,0.027509457,0.563475881,0.326303279,0.951017588,0.079116591,DB0065810020711_,2.536832683,-0.573630748,NA,10020711,Hyperphosphataemia,10027433,Metabolism and nutrition disorders,Metab,sevelamer,DB00658
,193515,DB01015,10069339,243,9644,421,8960,1.18201248988097e-14,0.536281588,0.454820031,0.63121627,6.90426628811583e-13,DB0101510069339_,28.00146669,-0.623095905,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,sulfamethoxazole,DB01015
,193530,DB00252,10019211,85,2147,35,1873,0.000177173,2.118206323,1.405676527,3.253107132,0.001300881,DB0025210019211_,6.644713611,0.750569657,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,phenytoin,DB00252
,193536,DB06292,10028813,65,1292,43,1190,0.115033292,1.392108657,0.924495761,2.114425514,0.233657902,DB0629210028813_,1.453897191,0.330819617,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dapagliflozin,DB06292
,193537,DB06292,10018484,37,1320,43,1190,0.306201653,0.775801978,0.482473104,1.242124304,0.473135645,DB0629210018484_,0.748373156,-0.253857975,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,dapagliflozin,DB06292
,193538,DB01276,10057362,54,1963,51,1460,0.231203191,0.787570396,0.523709378,1.185782787,0.387377351,DB0127610057362_,0.948355993,-0.238802521,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,exenatide,DB01276
,193591,DB00904,10028997,41,23028,29,14427,0.624535603,0.885744304,0.537014816,1.478536706,0.764330966,DB0090410028997_,0.268754383,-0.121326966,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ondansetron,DB00904
,193602,DB00843,10019063,69,2125,159,2014,3.92040545160699e-10,0.411372834,0.303439566,0.552945596,1.173665800632e-08,DB0084310019063_,18.26054873,-0.888255337,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,donepezil,DB00843
,193603,DB01062,10019063,40,4446,32,1713,0.003306534,0.481662439,0.293985465,0.79502058,0.014636619,DB0106210019063_,4.224228712,-0.730511744,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,oxybutynin,DB01062
,193604,DB06724,10019063,39,7890,19,3900,1,1.014615251,0.571448797,1.861470121,1,DB0672410019063_,0,0.014509477,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,calcium carbonate,DB06724
,193610,DB01065,10017955,21,4310,30,3021,0.014540333,0.490690852,0.266491504,0.887981815,0.048074547,DB0106510017955_,3.035002403,-0.711940979,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,melatonin,DB01065
,193611,DB00656,10027417,26,11987,49,6570,1.70913410832204e-07,0.290845658,0.173326209,0.477731096,2.95265133337133e-06,DB0065610027417_,12.73280703,-1.234962536,male,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,trazodone,DB00656
,193623,DB00316,10069339,896,64578,870,36083,3.4491574327739e-30,0.575422096,0.523136957,0.6330202,7.81561233797086e-28,DB0031610069339_,62.41625929,-0.552651427,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,193624,DB00656,10069339,133,11880,169,6450,3.83046722636995e-13,0.427292462,0.337128232,0.540631609,1.81575890072379e-11,DB0065610069339_,24.73193252,-0.850286579,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,trazodone,DB00656
,193625,DB00734,10069339,60,3990,67,4835,0.65455139,1.085165235,0.750961125,1.565110179,0.788326766,DB0073410069339_,0.237842598,0.081732265,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,risperidone,DB00734
,193626,DB00836,10069339,117,5418,128,3947,0.00202725,0.665934011,0.511983389,0.865450972,0.009831415,DB0083610069339_,4.622172369,-0.406564696,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,loperamide,DB00836
,193627,DB01065,10069339,49,4282,63,2988,0.001383471,0.54279702,0.36471269,0.803628645,0.007195201,DB0106510069339_,4.934340958,-0.611019842,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,melatonin,DB01065
,193628,DB01377,10069339,139,3657,89,2581,0.494294499,1.102280436,0.834466421,1.462171062,0.656818711,DB0137710069339_,0.420347234,0.097381158,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,magnesium oxide,DB01377
,193630,DB00734,10044565,33,4017,61,4841,0.048256118,0.651986359,0.412527037,1.014091061,0.121807576,DB0073410044565_,2.105312725,-0.427731639,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,193632,DB06262,10013968,119,3681,86,4228,0.001368718,1.589234574,1.189732442,2.130266401,0.007133953,DB0626210013968_,4.942889792,0.463252501,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,droxidopa,DB06262
,193639,DB00175,10047513,71,8060,50,6056,0.782236402,1.066947113,0.731392876,1.566753438,0.881447445,DB0017510047513_,0.126189899,0.064801405,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,pravastatin,DB00175
,193675,DB06403,10076308,57,21414,7,6654,0.017407886,2.530273023,1.151033255,6.579773733,0.055424667,DB0640310076308_,2.892730523,0.928327211,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ambrisentan,DB06403
,193677,DB00864,10009887,41,6828,47,8345,0.830012164,1.06612482,0.682933094,1.658430507,0.910798822,DB0086410009887_,0.093433238,0.06403041,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,193682,DB00476,10049414,40,17217,20,6157,0.240094357,0.715234483,0.407983505,1.292427838,0.397949376,DB0047610049414_,0.921430478,-0.335144842,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,193693,DB00213,10042727,36,18859,19,13402,0.338626599,1.346466846,0.751751522,2.486106709,0.507688806,DB0021310042727_,0.677886605,0.29748401,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,193701,DB08932,10007632,68,19375,9,6588,0.005363454,2.569156389,1.275732907,5.859943877,0.021630747,DB0893210007632_,3.833639513,0.943577592,NA,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,macitentan,DB08932
,193710,DB00203,10019641,40,13838,27,8911,0.900427522,0.954025464,0.570679764,1.617784555,0.956698706,DB0020310019641_,0.044266769,-0.047064916,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,sildenafil,DB00203
,193724,DB00190,10005734,36,3261,58,4616,0.59890935,0.878639378,0.561583384,1.358135354,0.7436826,DB0019010005734_,0.296140948,-0.129380729,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,carbidopa,DB00190
,193726,DB00727,10005734,35,3808,29,4144,0.315397135,1.313336967,0.778172178,2.232105918,0.48301417,DB0072710005734_,0.727709289,0.272571202,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,nitroglycerin,DB00727
,193729,DB00727,10024855,23,3820,30,4143,0.581720428,0.831512013,0.460369617,1.483425013,0.730032058,DB0072710024855_,0.314666831,-0.184509533,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,193730,DB00008,10066901,17,1508,38,1638,0.013794569,0.486040492,0.25612305,0.886578376,0.046006214,DB0000810066901_,3.078978809,-0.721463342,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,peginterferon alfa-2a,DB00008
,193740,DB00215,10060800,42,11061,13,5263,0.19485984,1.537214313,0.808623014,3.12398328,0.342848762,DB0021510060800_,1.070465856,0.42997189,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,citalopram,DB00215
,193742,DB01076,10061623,156,25591,163,25420,0.653759274,0.950643887,0.757804555,1.192251062,0.787753851,DB0107610061623_,0.23856961,-0.050615748,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,193760,DB01234,10034568,41,31584,33,32855,0.295987916,1.292412453,0.797068656,2.11023093,0.461860633,DB0123410034568_,0.772492094,0.256510591,NA,10034568,Peripheral coldness,10047065,Vascular disorders,Vasc,dexamethasone,DB01234
,193780,DB00390,10061623,42,4103,39,3262,0.501514699,0.85620406,0.538978534,1.362993496,0.663010883,DB0039010061623_,0.410963875,-0.155246544,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,193785,DB14500,10005483,32,7777,27,4046,0.073317183,0.61660081,0.357335998,1.071470047,0.167047386,DB1450010005483_,1.78947776,-0.483533449,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,potassium,DB14500
,193798,DB01041,10037377,27,3018,30,3088,0.79124117,0.920910166,0.525396185,1.607009653,0.886974333,DB0104110037377_,0.119939234,-0.082392787,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,thalidomide,DB01041
,193810,DB00695,10056520,52,27997,10,20518,1.46706124292057e-05,3.810770348,1.915286741,8.412298086,0.000152057,DB0069510056520_,8.791253822,1.33783136,female,10056520,Catheter site infection,10021881,Infections and infestations,Infec,furosemide,DB00695
,193823,DB01041,10013573,104,2941,68,3050,0.003273581,1.585965877,1.151965203,2.1954437,0.014521501,DB0104110013573_,4.232124892,0.461193608,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,thalidomide,DB01041
,193854,DB01217,10035664,55,2699,7,261,0.494830669,0.759884387,0.34039857,1.998319024,0.657228907,DB0121710035664_,0.419722909,-0.27458898,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,anastrozole,DB01217
,193861,DB01610,10013710,34,907,19,1199,0.002924,2.36464855,1.301227914,4.419087092,0.013233015,DB0161010013710_,4.325040465,0.860629406,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,valganciclovir,DB01610
,193867,DB00864,10013722,52,6817,100,8292,0.008534171,0.632532701,0.442751279,0.894480318,0.031366943,DB0086410013722_,3.46200071,-0.458023359,NA,10013722,Drug level increased,10022891,Investigations,Inv,tacrolimus,DB00864
,193887,DB01041,10043607,49,2996,58,3060,0.495121149,0.862895945,0.57558184,1.289074324,0.657501675,DB0104110043607_,0.419307967,-0.147461168,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,thalidomide,DB01041
,193888,DB00423,10028334,68,2399,14,1026,0.010106223,2.076927139,1.150531427,4.01768173,0.035875761,DB0042310028334_,3.327693386,0.730889464,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,methocarbamol,DB00423
,193890,DB08910,10029216,61,16683,29,17459,0.000429505,2.201250427,1.392037387,3.55493854,0.002719385,DB0891010029216_,5.907349594,0.789025575,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,pomalidomide,DB08910
,193899,DB00169,10016338,60,38631,17,18158,0.06677688,1.658940638,0.954923955,3.033715389,0.155536085,DB0016910016338_,1.860877514,0.506179229,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,193910,DB00207,10076309,52,9028,18,5437,0.047113297,1.739734546,0.999824731,3.163562699,0.119672693,DB0020710076309_,2.122994823,0.553732542,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,azithromycin,DB00207
,193926,DB01156,10064355,62,13560,29,6299,1,0.993129173,0.628605953,1.602903571,1,DB0115610064355_,0,-0.00689454,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,193937,DB08906,10011906,70,2123,72,1086,6.29302995582061e-05,0.49742926,0.349776309,0.707092026,0.00053653,DB0890610011906_,7.530387515,-0.698301924,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,fluticasone furoate,DB08906
,193938,DB00531,10008190,33,7219,20,6496,0.170484198,1.484702091,0.826138443,2.733299601,0.311488245,DB0053110008190_,1.166393678,0.39521414,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,193939,DB01041,10008190,45,3000,26,3092,0.022683927,1.78366914,1.073909462,3.020121881,0.068165889,DB0104110008190_,2.685810999,0.578672557,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,thalidomide,DB01041
,193955,DB00814,10047340,57,8230,17,3398,0.30432333,1.384272432,0.792463947,2.542513628,0.470980849,DB0081410047340_,0.752937846,0.325174682,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,meloxicam,DB00814
,193965,DB00874,10070863,40,3295,14,1962,0.09063732,1.701120968,0.903292659,3.39416614,0.19622782,DB0087410070863_,1.628478947,0.531287427,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,guaifenesin,DB00874
,193966,DB00904,10070863,142,22927,85,14371,0.784497377,1.047153638,0.794078668,1.387890685,0.882992059,DB0090410070863_,0.124439072,0.046075662,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,193976,DB00343,10020100,37,8699,16,5079,0.392116585,1.350148586,0.731910926,2.602377216,0.561985241,DB0034310020100_,0.576279691,0.30021465,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,193977,DB00678,10020100,59,15540,11,10713,7.99659157523261e-06,3.697421396,1.922674948,7.808511914,8.94427274702081e-05,DB0067810020100_,9.321912054,1.307635657,female,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,193983,DB01137,10020751,89,7683,45,5548,0.05304236,1.42814234,0.985264752,2.095708953,0.130716148,DB0113710020751_,2.034727118,0.356374537,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,levofloxacin,DB01137
,193997,DB00814,10015150,81,8206,27,3388,0.394966,1.238566518,0.790865482,1.995906117,0.564835763,DB0081410015150_,0.571220275,0.213954677,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,meloxicam,DB00814
,193999,DB00678,10024774,35,15564,26,10698,0.794863395,0.925289533,0.540935267,1.601680751,0.88886159,DB0067810024774_,0.117813747,-0.077648582,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,losartan,DB00678
,194001,DB01373,10024774,59,22661,26,7355,0.206471475,0.736524379,0.456639055,1.218341986,0.357046231,DB0137310024774_,1.029890007,-0.305812942,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,calcium,DB01373
,194004,DB01611,10029331,97,11816,21,2340,0.708887962,0.914726673,0.564943542,1.54743047,0.826298175,DB0161110029331_,0.190799584,-0.089129976,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,hydroxychloroquine,DB01611
,194007,DB00814,10061623,52,8235,20,3395,0.896702698,1.071881324,0.627919283,1.898442904,0.956301489,DB0081410061623_,0.044682051,0.069415351,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,194008,DB00924,10061623,56,10106,35,4216,0.065123489,0.667504877,0.429192984,1.05101093,0.152652686,DB0092410061623_,1.879589962,-0.404208582,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,194009,DB01611,10061623,126,11787,18,2343,0.215209521,1.391416282,0.843444483,2.428674831,0.36764496,DB0161110061623_,1.00063759,0.330322136,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,194013,DB01041,10017413,40,3005,52,3066,0.293467901,0.784878309,0.50474944,1.212464323,0.459127658,DB0104110017413_,0.778426985,-0.242226594,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,thalidomide,DB01041
,194017,DB00404,10051076,48,19844,31,9831,0.281203699,0.767127093,0.478049913,1.24752739,0.445173561,DB0040410051076_,0.809291049,-0.26510279,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,194020,DB00334,10061428,42,2807,29,2783,0.151951386,1.435795563,0.870706421,2.397251817,0.286681178,DB0033410061428_,1.249384559,0.361719095,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,olanzapine,DB00334
,194083,DB00887,10007882,35,2306,17,1798,0.122247909,1.60509731,0.872125712,3.065842743,0.244672678,DB0088710007882_,1.40783397,0.473184384,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,bumetanide,DB00887
,194097,DB00682,10017413,81,19378,63,16301,0.675595598,1.081582605,0.76800225,1.529083102,0.803379592,DB0068210017413_,0.21892796,0.078425343,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,warfarin,DB00682
,194098,DB00736,10017413,53,10538,37,5516,0.182976677,0.749830923,0.482835817,1.175300828,0.327647794,DB0073610017413_,1.115816047,-0.287907534,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,esomeprazole,DB00736
,194100,DB00281,10013887,38,11420,27,5644,0.148573525,0.695565157,0.413214237,1.185953639,0.282008602,DB0028110013887_,1.265817706,-0.363030588,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,194109,DB00972,10013700,50,2454,10,1169,0.011294086,2.381359765,1.188210399,5.286168935,0.039208345,DB0097210013700_,3.238865662,0.867671654,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,azelastine,DB00972
,194124,DB01041,10023547,26,3019,35,3083,0.305357982,0.758641009,0.437354754,1.300436366,0.472153228,DB0104110023547_,0.750451711,-0.276226592,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,thalidomide,DB01041
,194128,DB00635,10000880,52,33001,73,23721,0.000251343,0.512036453,0.351531202,0.741096661,0.001743611,DB0063510000880_,6.351797115,-0.669359458,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,194139,DB00186,10017413,98,16803,60,9948,0.868954991,0.966970444,0.693515703,1.357948949,0.941681382,DB0018610017413_,0.060088297,-0.033587349,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,lorazepam,DB00186
,194140,DB00215,10017413,59,11044,24,5252,0.557993121,1.169043506,0.715196491,1.967452471,0.710996397,DB0021510017413_,0.341087917,0.156185898,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,citalopram,DB00215
,194142,DB00635,10017413,76,32977,73,23721,0.081009793,0.748893719,0.53569849,1.047555402,0.180056014,DB0063510017413_,1.714487287,-0.289158202,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,prednisone,DB00635
,194143,DB06228,10017413,48,15864,36,16040,0.190383215,1.348108197,0.85646627,2.1392082,0.337074883,DB0622810017413_,1.087450169,0.298702274,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,rivaroxaban,DB06228
,194144,DB00448,10046306,49,5096,19,3105,0.102871446,1.571274978,0.906386407,2.831801697,0.215301852,DB0044810046306_,1.535714275,0.451887378,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,lansoprazole,DB00448
,194156,DB01261,10013710,23,3758,45,3258,0.001355741,0.44315527,0.255322464,0.74992846,0.007077588,DB0126110013710_,4.950822092,-0.813835073,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,sitagliptin,DB01261
,194158,DB01065,10010264,109,4222,67,2984,0.394760151,1.149774266,0.837231421,1.588891346,0.564664267,DB0106510010264_,0.571523943,0.139565632,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,194159,DB01065,10010305,58,4273,90,2961,1.7783996770414e-06,0.446617043,0.314304267,0.630409066,2.38800692265814e-05,DB0106510010305_,10.64246637,-0.806053778,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,melatonin,DB01065
,194168,DB00374,10027175,123,17593,26,5698,0.055085395,1.532130761,0.99611704,2.440612026,0.134500508,DB0037410027175_,2.006187305,0.426659421,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,194170,DB00404,10037400,56,19836,16,9846,0.059203901,1.737266454,0.981889842,3.246430293,0.141993206,DB0040410037400_,1.951976067,0.552312875,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,194175,DB00404,10061355,47,19845,38,9824,0.027956184,0.612278239,0.39048212,0.965709554,0.080129579,DB0040410061355_,2.524110223,-0.49056846,NA,10061355,Poisoning,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,194182,DB00230,10014020,44,19630,11,8640,0.106414611,1.760539368,0.894174455,3.781439778,0.220748799,DB0023010014020_,1.510729878,0.565620221,NA,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,pregabalin,DB00230
,194183,DB00230,10076308,652,19022,230,8421,0.003329129,1.254910757,1.075671353,1.468146495,0.0147131,DB0023010076308_,4.219017056,0.22706446,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,194218,DB00761,10059168,45,15262,9,8616,0.002577399,2.822586939,1.361703493,6.570022612,0.011948312,DB0076110059168_,4.427165296,1.037653819,female,10059168,Oxygen consumption increased,10022891,Investigations,Inv,potassium chloride,DB00761
,194223,DB09140,10059168,145,3596,45,1753,0.009088862,1.57067048,1.111101326,2.257560589,0.03298367,DB0914010059168_,3.411742676,0.451502585,NA,10059168,Oxygen consumption increased,10022891,Investigations,Inv,oxygen,DB09140
,194245,DB00661,10003549,76,3452,39,1556,0.541327825,0.878421294,0.5865136,1.334031525,0.696687731,DB0066110003549_,0.361417987,-0.129628967,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,verapamil,DB00661
,194262,DB01098,10008531,58,8091,44,7165,0.486342622,1.167305989,0.774240855,1.770935271,0.650216139,DB0109810008531_,0.43045045,0.15469852,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,194278,DB06684,10019211,48,699,9,326,0.011653342,2.485628448,1.187813949,5.832803338,0.040226949,DB0668410019211_,3.213218123,0.910525524,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,vilazodone,DB06684
,194280,DB00795,10028810,46,4523,18,1485,0.560203822,0.839042084,0.475439982,1.542633272,0.712831362,DB0079510028810_,0.338510405,-0.175494415,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,sulfasalazine,DB00795
,194281,DB01098,10028810,108,8041,61,7148,0.005132036,1.57381755,1.137382841,2.194765899,0.020884987,DB0109810028810_,3.868724689,0.453504228,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,rosuvastatin,DB01098
,194283,DB01036,10028813,71,1430,11,411,0.056829654,1.854523411,0.964829105,3.919666027,0.137484348,DB0103610028813_,1.984245198,0.617627742,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,tolterodine,DB01036
,194291,DB08895,10061428,153,27961,23,6623,0.043115384,1.57564109,1.011369666,2.562517223,0.111902035,DB0889510061428_,2.190131479,0.454662231,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,tofacitinib,DB08895
,194292,DB00230,10027374,78,19596,23,8628,0.104044261,1.493174402,0.926981567,2.493451689,0.217116814,DB0023010027374_,1.527319755,0.400904325,NA,10027374,Mental impairment,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,194318,DB00996,10064911,96,38857,30,22395,0.002899024,1.844282376,1.212371678,2.880521572,0.013139208,DB0099610064911_,4.33215452,0.612090246,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,194330,DB06674,10048959,50,4456,8,1482,0.065228129,2.078567209,0.974735929,5.088108433,0.152843448,DB0667410048959_,1.878341096,0.731678815,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,golimumab,DB06674
,194348,DB09153,10069339,112,7687,196,5503,2.25386422671178e-14,0.409101662,0.320543872,0.520079251,1.26317315989593e-12,DB0915310069339_,27.39739418,-0.893791591,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,sodium chloride,DB09153
,194357,DB00993,10011906,41,3208,33,1586,0.045950016,0.614291494,0.377343422,1.006968286,0.117404245,DB0099310011906_,2.142132211,-0.487285717,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,azathioprine,DB00993
,194359,DB00338,10013663,31,33643,19,22253,0.885433397,1.079211221,0.590531205,2.022433235,0.952314613,DB0033810013663_,0.048859823,0.076230423,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,194363,DB01224,10013663,26,8082,37,5880,0.010046515,0.511281566,0.29691839,0.86845758,0.035704794,DB0122410013663_,3.332470313,-0.670834831,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,194391,DB00341,10064911,47,11358,10,5058,0.030747666,2.092947235,1.042676963,4.649536348,0.086374096,DB0034110064911_,2.449067466,0.738573233,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,194415,DB13961,10003658,85,9372,117,6297,5.06656664561032e-07,0.488143939,0.364062273,0.652273557,7.8499678325887e-06,DB1396110003658_,11.75500112,-0.71714496,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,fish oil,DB13961
,194419,DB09053,10028596,18,2267,47,4005,0.193811083,0.676629448,0.368908274,1.190599633,0.34146954,DB0905310028596_,1.0744968,-0.3906315,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,ibrutinib,DB09053
,194422,DB09053,10069339,25,2260,102,3950,7.50351500807936e-05,0.428429472,0.264128972,0.671165053,0.000622962,DB0905310069339_,7.381024414,-0.847629148,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ibrutinib,DB09053
,194423,DB13961,10069339,75,9382,103,6311,3.24891321784811e-06,0.489823956,0.358194411,0.667215294,4.05962593792886e-05,DB1396110069339_,10.11183463,-0.713709226,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,fish oil,DB13961
,194431,DB01268,10013573,71,2072,97,3033,0.690050376,1.071428853,0.773432154,1.47825889,0.813015717,DB0126810013573_,0.207004838,0.068993134,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sunitinib,DB01268
,194450,DB00364,10003549,83,2667,53,1347,0.197165306,0.791012324,0.550018587,1.145978608,0.345614542,DB0036410003549_,1.062431165,-0.234441731,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sucralfate,DB00364
,194453,DB00390,10021036,32,4113,21,3280,0.579340179,1.21516246,0.677967499,2.221864385,0.728070407,DB0039010021036_,0.317357522,0.19487778,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,digoxin,DB00390
,194464,DB00641,10039117,32,14092,38,12437,0.231560937,0.743219002,0.449203883,1.222531943,0.387816065,DB0064110039117_,0.947224111,-0.296764523,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,194465,DB00761,10039117,39,15268,21,8604,1,1.046559569,0.600269915,1.873820853,1,DB0076110039117_,0,0.045508184,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,194473,DB00364,10061428,52,2698,43,1357,0.020683422,0.608296872,0.396047612,0.93859806,0.06346393,DB0036410061428_,2.757283564,-0.49709224,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,sucralfate,DB00364
,194492,DB00091,10003997,16,5494,37,2633,5.05288446598876e-08,0.207296214,0.107436604,0.382721623,9.7622247841613e-07,DB0009110003997_,13.83957533,-1.573606525,male,10003997,Bacteraemia,10021881,Infections and infestations,Infec,cyclosporine,DB00091
,194562,DB09153,10017885,34,7765,24,5675,1,1.035362872,0.595443637,1.827003534,1,DB0915310017885_,0,0.034751967,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,194577,DB08932,10021036,67,19376,24,6573,0.80967923,0.947026268,0.585678748,1.580296382,0.897443276,DB0893210021036_,0.108205363,-0.054428448,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,macitentan,DB08932
,194629,DB08932,10048961,47,19396,11,6586,0.293726344,1.450771743,0.741090087,3.103923012,0.459463622,DB0893210048961_,0.77769551,0.372095652,NA,10048961,Localised oedema,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,194645,DB00588,10053483,42,16482,12,8456,0.083431518,1.795617605,0.927464471,3.748659253,0.184153962,DB0058810053483_,1.691983122,0.585349032,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,194650,DB08932,10053483,240,19203,50,6547,0.00109142,1.63639391,1.200648912,2.269363369,0.005918098,DB0893210053483_,5.129740098,0.492494986,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,194687,DB00704,10011906,49,4307,122,5072,5.8429471627352e-06,0.473024416,0.331528022,0.665900519,6.77019467368282e-05,DB0070410011906_,9.600395623,-0.748608273,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,194703,DB11089,10021143,93,10082,88,8319,0.368612579,0.872024317,0.643489229,1.182501792,0.538285042,DB1108910021143_,0.619367041,-0.136937969,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,194704,DB01076,10023676,32,25715,28,25555,0.698803329,1.135742758,0.662209572,1.95837427,0.81897108,DB0107610023676_,0.199706507,0.127286849,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,194707,DB00497,10027417,97,19170,59,16316,0.044077825,1.399285703,1.001432206,1.969564419,0.113748528,DB0049710027417_,2.173765166,0.335961894,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,194708,DB01234,10027417,36,31589,56,32832,0.060641555,0.668160084,0.426828546,1.03399614,0.144603399,DB0123410027417_,1.933760466,-0.403227488,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,194723,DB00497,10001497,81,19186,100,16275,0.013435841,0.687116511,0.505776103,0.93108085,0.045040313,DB0049710001497_,3.100197352,-0.375251408,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,194749,DB00186,10069339,228,16673,203,9805,2.33271195610735e-05,0.66053692,0.543340461,0.803363997,0.000227726,DB0018610069339_,8.38736564,-0.41470226,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,lorazepam,DB00186
,194750,DB00448,10069339,327,4818,278,2846,2.30112459782702e-05,0.694873376,0.586344866,0.823860707,0.000225103,DB0044810069339_,8.398954401,-0.364025642,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,lansoprazole,DB00448
,194751,DB00581,10069339,42,2071,71,1998,0.00414631,0.570777679,0.378177843,0.852189697,0.01758544,DB0058110069339_,4.04068397,-0.5607555,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,lactulose,DB00581
,194752,DB09037,10069339,34,2492,67,2768,0.006463962,0.563726781,0.360322299,0.867471721,0.025126576,DB0903710069339_,3.683829202,-0.573185575,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,pembrolizumab,DB09037
,194753,DB11089,10069339,194,9981,240,8167,2.56284567222887e-05,0.661445919,0.543280262,0.804452895,0.000246621,DB1108910069339_,8.307659708,-0.413327054,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,docusate,DB11089
,194754,DB00198,10012735,79,1196,32,971,0.000832694,2.003696142,1.300519219,3.151453311,0.004734448,DB0019810012735_,5.352890043,0.694993546,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,oseltamivir,DB00198
,194772,DB00198,10028813,82,1193,38,965,0.005945074,1.745076207,1.162057233,2.661354125,0.023495154,DB0019810028813_,3.75096109,0.556798226,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,oseltamivir,DB00198
,194773,DB00198,10047700,102,1173,49,954,0.002948305,1.692608755,1.17875147,2.457823409,0.013312067,DB0019810047700_,4.319084367,0.526270981,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,oseltamivir,DB00198
,194776,DB00715,10021789,39,4804,16,2271,0.771944655,1.152250706,0.627674102,2.2135533,0.875159166,DB0071510021789_,0.133349505,0.141717165,NA,10021789,Infection,10021881,Infections and infestations,Infec,paroxetine,DB00715
,194792,DB00169,10005911,39,38652,19,18156,0.888601112,0.964200639,0.543753354,1.766983512,0.953848174,DB0016910005911_,0.047250767,-0.036455874,NA,10005911,Body temperature increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,194801,DB01592,10008469,47,6229,18,3049,0.427827914,1.278019816,0.726962915,2.342415122,0.596354496,DB0159210008469_,0.516919997,0.245311861,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,194804,DB00635,10039906,170,32883,129,23665,0.680863602,0.94842866,0.749484351,1.202502737,0.807023985,DB0063510039906_,0.21440189,-0.052948705,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,194806,DB01592,10039906,55,6221,17,3050,0.102146062,1.586111621,0.905023827,2.920317654,0.214184454,DB0159210039906_,1.540917699,0.4612855,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,iron,DB01592
,194810,DB00451,10010144,423,46848,185,15234,0.001074156,0.74352202,0.623441306,0.889472683,0.005842563,DB0045110010144_,5.142585751,-0.296356897,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,194811,DB01267,10010144,26,2826,37,3678,0.79889757,0.9145475,0.53040749,1.555655801,0.891356522,DB0126710010144_,0.115010795,-0.089325871,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,194831,DB05676,10023230,65,47064,37,25292,0.835463614,0.944075205,0.620907299,1.454699634,0.914862473,DB0567610023230_,0.088981527,-0.05754945,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,194834,DB05676,10056819,394,46735,242,25087,0.103381833,0.873958517,0.742217221,1.030740299,0.216094749,DB0567610056819_,1.532038312,-0.134722368,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,194843,DB00818,10063181,18,1402,45,1632,0.006846208,0.465741424,0.252500288,0.825204053,0.026345447,DB0081810063181_,3.636459801,-0.764124682,NA,10063181,Propofol infusion syndrome,10027433,Metabolism and nutrition disorders,Metab,propofol,DB00818
,194844,DB00818,10069339,44,1376,107,1570,2.41824483460058e-05,0.469301093,0.320121622,0.678125721,0.000234682,DB0081810069339_,8.357280005,-0.756510728,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,propofol,DB00818
,194846,DB01137,10039906,48,7724,41,5552,0.450975791,0.841534919,0.54224907,1.311339871,0.618647183,DB0113710039906_,0.480220148,-0.17252777,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,194896,DB09037,10028372,22,2504,30,2805,0.577043284,0.821516344,0.450253551,1.476978167,0.726231208,DB0903710028372_,0.319886846,-0.196603447,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,pembrolizumab,DB09037
,194898,DB05351,10003549,54,2669,26,1105,0.5361163,0.859920952,0.526104509,1.438398917,0.692472577,DB0535110003549_,0.367486642,-0.150914811,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,dexlansoprazole,DB05351
,194899,DB00472,10012174,98,10661,40,4272,0.92472877,0.981747316,0.671871523,1.458489327,0.967593918,DB0047210012174_,0.032942786,-0.018421319,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,fluoxetine,DB00472
,194935,DB05676,10013950,36,47093,20,25309,0.889396096,0.967338233,0.545091546,1.763988634,0.954019727,DB0567610013950_,0.04707093,-0.033207069,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,194947,DB00869,10053762,36,1269,37,892,0.117170119,0.68405079,0.416507898,1.122421731,0.236887567,DB0086910053762_,1.440169651,-0.37972311,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,dorzolamide,DB00869
,194951,DB00341,10017918,45,11360,13,5055,0.199769912,1.540290111,0.815675375,3.11513891,0.348784599,DB0034110017918_,1.053300743,0.431970782,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,cetirizine,DB00341
,194953,DB00668,10017918,48,10043,15,4288,0.33558946,1.366204003,0.751106346,2.629848473,0.504766672,DB0066810017918_,0.683658992,0.312036094,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,epinephrine,DB00668
,194957,DB01075,10017918,62,19886,20,11077,0.037152211,1.726748955,1.028162992,3.020205246,0.09988346,DB0107510017918_,2.303751171,0.546240424,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,194962,DB09038,10003549,30,2218,39,2502,0.627499571,0.867751587,0.518683834,1.438661887,0.766909446,DB0903810003549_,0.265386548,-0.141849795,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,empagliflozin,DB09038
,194991,DB01075,10018100,52,19896,17,11080,0.059098873,1.703418551,0.96866265,3.143826792,0.141808576,DB0107510018100_,1.953277184,0.532637144,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,195009,DB00048,10033371,13,221,40,809,0.608141839,1.189534919,0.573283501,2.318754205,0.750956786,DB0004810033371_,0.286407171,0.173562406,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,collagenase clostridium histolyticum,DB00048
,195029,DB01109,10002855,50,4362,34,4236,0.124567923,1.428045262,0.90345889,2.28196459,0.247928509,DB0110910002855_,1.394614846,0.356306559,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,heparin,DB01109
,195031,DB00028,10052904,69,13389,20,5595,0.162684856,1.441714403,0.864891376,2.506827034,0.300958683,DB0002810052904_,1.200782291,0.365832963,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,human immunoglobulin g,DB00028
,195039,DB01060,10042682,38,8549,22,5059,1,1.02213895,0.588531191,1.816513498,1,DB0106010042682_,0,0.021897442,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,195051,DB00281,10054112,74,11384,40,5631,0.689732412,0.915094151,0.613864485,1.382016432,0.812888491,DB0028110054112_,0.207161336,-0.088728322,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,lidocaine,DB00281
,195052,DB08900,10054112,58,953,16,421,0.118375634,1.600915936,0.895215693,3.020122384,0.238772877,DB0890010054112_,1.432242485,0.470575925,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,teduglutide,DB08900
,195058,DB01075,10002948,35,19913,17,11080,0.772355444,1.14555324,0.624477092,2.181618656,0.875398337,DB0107510002948_,0.133076254,0.1358877,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,195061,DB01075,10013774,43,19905,11,11086,0.022000805,2.177100483,1.103459635,4.683745015,0.066631082,DB0107510013774_,2.708584107,0.777993938,NA,10013774,Dry eye,10015919,Eye disorders,Eye,diphenhydramine,DB01075
,195066,DB01075,10029410,45,19903,29,11068,0.545140807,0.862919385,0.528982842,1.428149115,0.69996708,DB0107510029410_,0.356721973,-0.147434005,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,195098,DB11089,10040844,31,10144,31,8376,0.523169342,0.825721073,0.485006636,1.405791474,0.681565552,DB1108910040844_,0.383362844,-0.191498247,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,docusate,DB11089
,195125,DB00230,10012374,97,19577,21,8630,0.002481527,2.036140497,1.259604145,3.439530602,0.011599948,DB0023010012374_,4.456754638,0.711056102,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,195126,DB00656,10012374,51,11962,22,6597,0.391475746,1.278482244,0.760754186,2.215714704,0.561325586,DB0065610012374_,0.577454175,0.245673627,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,195127,DB00996,10012374,108,38845,47,22378,0.11298287,1.323762597,0.931199122,1.907194716,0.230544171,DB0099610012374_,1.467312804,0.280478134,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,195130,DB00175,10040984,30,8101,24,6082,0.890630816,0.93847995,0.529810135,1.679238553,0.954671384,DB0017510040984_,0.046388098,-0.063493787,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,pravastatin,DB00175
,195131,DB00193,10040984,60,19260,26,8676,0.907705978,1.039517901,0.645521959,1.717579299,0.958771936,DB0019310040984_,0.042102046,0.038757049,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,195147,DB00476,10024774,44,17213,18,6159,0.665088532,0.874669088,0.494708017,1.609476147,0.796149561,DB0047610024774_,0.22796822,-0.133909649,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,duloxetine,DB00476
,195148,DB00996,10024774,101,38852,81,22344,0.030590185,0.717134508,0.529780262,0.973313746,0.086014443,DB0099610024774_,2.453240053,-0.332491858,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,195150,DB00051,10039203,53,25678,31,11389,0.236584493,0.758279748,0.477655119,1.222842091,0.39382055,DB0005110039203_,0.93185993,-0.276702901,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,195164,DB00904,10076309,239,22830,78,14378,1.5486504256171e-07,1.929691604,1.487194843,2.527076561,2.70204290988022e-06,DB0090410076309_,12.82150244,0.6573602,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,195173,DB00531,10076309,42,7210,49,6467,0.246501869,0.768831359,0.496031487,1.187022013,0.405590086,DB0053110076309_,0.90241227,-0.262883633,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclophosphamide,DB00531
,195175,DB00864,10076309,53,6816,72,8320,0.588760089,0.898570297,0.617087327,1.301107707,0.735582809,DB0086410076309_,0.307092157,-0.106950338,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tacrolimus,DB00864
,195178,DB06605,10018964,68,14005,97,12936,0.006151196,0.647536808,0.467351649,0.892874959,0.024140975,DB0660510018964_,3.723844667,-0.43457964,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,195179,DB06605,10035664,548,13525,441,12592,0.025313856,1.156902555,1.016252799,1.317582539,0.074195643,DB0660510035664_,2.601049844,0.145746222,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,apixaban,DB06605
,195180,DB06605,10062237,56,14017,61,12972,0.404587956,0.849597678,0.579907223,1.242598717,0.57436172,DB0660510062237_,0.554495907,-0.162992362,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,apixaban,DB06605
,195183,DB00563,10070325,61,46585,28,15320,0.141761841,0.71645205,0.450790706,1.164696833,0.272214633,DB0056310070325_,1.301164433,-0.333443957,NA,10070325,Mycobacterium tuberculosis complex test positive,10022891,Investigations,Inv,methotrexate,DB00563
,195189,DB00203,10049438,95,13783,47,8891,0.143332885,1.303845943,0.908914189,1.893021743,0.274509445,DB0020310049438_,1.292769612,0.265318315,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,195190,DB01240,10049438,51,5700,17,1559,0.460728115,0.820549722,0.464502112,1.520046805,0.628059252,DB0124010049438_,0.465120767,-0.197780771,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,195207,DB00736,10076308,53,10538,25,5528,0.720945092,1.112092117,0.678163403,1.869761453,0.835410838,DB0073610076308_,0.179831654,0.106243031,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,esomeprazole,DB00736
,195223,DB00514,10011906,194,1972,137,1399,1,1.004596049,0.794226058,1.27333455,1,DB0051410011906_,0,0.00458552,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dextromethorphan,DB00514
,195241,DB00363,10039906,29,4599,57,6831,0.227063666,0.755708785,0.465123207,1.203903548,0.382256922,DB0036310039906_,0.961662326,-0.280099182,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,clozapine,DB00363
,195242,DB00734,10039906,46,4004,71,4831,0.224154878,0.781726295,0.526069134,1.151751796,0.378721357,DB0073410039906_,0.97095455,-0.246250606,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,195243,DB00215,10013654,377,10726,346,4930,4.794603012205e-19,0.500819619,0.429978611,0.58349781,4.54968015075121e-17,DB0021510013654_,37.62888965,-0.691509285,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,195260,DB01156,10000381,34,13588,23,6305,0.198705084,0.685934513,0.392071855,1.220690068,0.347490356,DB0115610000381_,1.057018368,-0.376973118,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,195261,DB01224,10000381,52,8056,42,5875,0.675385962,0.902913503,0.588790125,1.391889847,0.80322693,DB0122410000381_,0.219118002,-0.102128519,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,195269,DB00620,10007882,49,4779,23,3109,0.225951105,1.385909002,0.826475899,2.388547182,0.380822981,DB0062010007882_,0.96542063,0.326356243,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,triamcinolone,DB00620
,195271,DB00864,10007882,29,6840,42,8350,0.550373568,0.842915641,0.505800074,1.387145658,0.704616791,DB0086410007882_,0.350101182,-0.170888396,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,195272,DB09053,10007882,22,2263,46,4006,0.611877536,0.84662394,0.483714531,1.440597152,0.753852039,DB0905310007882_,0.282559165,-0.166498674,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,ibrutinib,DB09053
,195276,DB00169,10012318,47,38644,11,18164,0.034431706,2.008305962,1.026337174,4.29494734,0.094269817,DB0016910012318_,2.361594211,0.697291562,NA,10012318,Dental caries,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,195359,DB00169,10039906,293,38398,161,18014,0.117152527,0.853788432,0.701446117,1.042196895,0.236864288,DB0016910039906_,1.440267924,-0.158071854,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,195360,DB00196,10039906,38,5045,25,3260,1,0.982196006,0.576408834,1.701088637,1,DB0019610039906_,0,-0.017964391,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,fluconazole,DB00196
,195362,DB00281,10039906,150,11308,62,5609,0.240699313,1.200014945,0.885294809,1.643447621,0.398688099,DB0028110039906_,0.919575875,0.182334011,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,195363,DB00338,10039906,241,33433,170,22102,0.543996077,0.937184414,0.766377231,1.148171277,0.699077779,DB0033810039906_,0.357993271,-0.064875202,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,195365,DB00381,10039906,215,29145,146,22741,0.201782887,1.149007958,0.926166762,1.428744782,0.351179447,DB0038110039906_,1.046457942,0.138898925,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,195366,DB00404,10039906,204,19688,72,9790,0.012159307,1.408880108,1.070649581,1.871843505,0.04159388,DB0040410039906_,3.179802227,0.342795139,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,195367,DB00557,10039906,58,5929,50,3017,0.007621743,0.590288831,0.396314804,0.882004639,0.028652389,DB0055710039906_,3.552518448,-0.527143318,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,195368,DB00572,10039906,31,2871,22,2104,1,1.032643041,0.577096082,1.877608639,1,DB0057210039906_,0,0.032121574,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,atropine,DB00572
,195371,DB00688,10039906,47,6443,27,5351,0.129663463,1.445662359,0.880737262,2.417474816,0.255181501,DB0068810039906_,1.36578022,0.368567596,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,mycophenolate mofetil,DB00688
,195373,DB00787,10039906,71,16929,81,17167,0.515617443,0.888869752,0.636604735,1.238721414,0.675362934,DB0078710039906_,0.392505052,-0.117804565,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,195374,DB00813,10039906,110,10462,59,10109,0.00025979,1.801440101,1.299695251,2.518607377,0.001793794,DB0081310039906_,6.323422359,0.588586401,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,195375,DB00864,10039906,69,6800,51,8341,0.007308888,1.659462103,1.137123146,2.435625582,0.027704104,DB0086410039906_,3.586174717,0.506493516,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,tacrolimus,DB00864
,195377,DB01069,10039906,108,6592,32,2363,0.384732197,1.209786401,0.806290892,1.860955674,0.554818994,DB0106910039906_,0.589113356,0.190443816,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,195378,DB01225,10039906,50,4994,31,4609,0.093602434,1.488494974,0.930590447,2.415012211,0.201102863,DB0122510039906_,1.603938744,0.397765525,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,enoxaparin,DB01225
,195379,DB01377,10039906,32,3764,26,2644,0.594242693,0.864569134,0.497876316,1.514327152,0.740163445,DB0137710039906_,0.300884245,-0.145524007,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,magnesium oxide,DB01377
,195404,DB00572,10047895,94,2808,61,2065,0.508954023,1.133178554,0.808024853,1.599171482,0.669437756,DB0057210047895_,0.401317089,0.125026564,NA,10047895,Weight decreased,10022891,Investigations,Inv,atropine,DB00572
,195405,DB00582,10047895,19,1111,33,1541,0.480103509,0.798663497,0.426677551,1.455008606,0.644946741,DB0058210047895_,0.438587538,-0.224815577,NA,10047895,Weight decreased,10022891,Investigations,Inv,voriconazole,DB00582
,195408,DB00582,10048294,25,1105,43,1531,0.45550348,0.805598663,0.468529413,1.358373829,0.622923907,DB0058210048294_,0.473330907,-0.216169598,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,voriconazole,DB00582
,195412,DB01377,10048294,31,3765,29,2641,0.292670774,0.749881555,0.436043841,1.293036827,0.458262422,DB0137710048294_,0.780313285,-0.287840011,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,magnesium oxide,DB01377
,195418,DB00864,10051055,23,6846,31,8361,0.784828011,0.906159079,0.504040805,1.606945377,0.883212924,DB0086410051055_,0.12418897,-0.098540404,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,tacrolimus,DB00864
,195501,DB00136,10028334,53,2039,14,1668,5.71672729655772e-05,3.095962003,1.686205846,6.06466211,0.00049486,DB0013610028334_,7.611236076,1.130098683,female,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,calcitriol,DB00136
,195502,DB00136,10064848,30,2062,26,1656,0.788006884,0.92667858,0.527401627,1.638238516,0.885160724,DB0013610064848_,0.121986041,-0.076148505,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,calcitriol,DB00136
,195503,DB00175,10064848,59,8072,53,6053,0.339952529,0.834781934,0.565320921,1.235273458,0.509110459,DB0017510064848_,0.675090275,-0.180584745,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,pravastatin,DB00175
,195505,DB00480,10064848,80,67348,79,67583,0.936889001,1.016193603,0.735120158,1.404966797,0.976936523,DB0048010064848_,0.023333601,0.016063885,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,195506,DB00787,10064848,49,16951,45,17203,0.679881079,1.10506846,0.721675108,1.695662732,0.806401975,DB0078710064848_,0.215172933,0.099907287,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,acyclovir,DB00787
,195507,DB00863,10064848,268,10405,147,5693,1,0.997508371,0.810500864,1.231515509,1,DB0086310064848_,0,-0.002494738,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,ranitidine,DB00863
,195508,DB00999,10064848,111,21319,68,12171,0.641068847,0.931911818,0.682388411,1.280627034,0.777936551,DB0099910064848_,0.251110313,-0.070517084,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,hydrochlorothiazide,DB00999
,195509,DB01156,10064848,52,13570,21,6307,0.70556475,1.150856142,0.680617403,2.013350351,0.823597413,DB0115610064848_,0.194073445,0.140506136,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,bupropion,DB01156
,195510,DB01234,10064848,61,31564,63,32825,1,1.006936573,0.696066874,1.455765144,1,DB0123410064848_,0,0.006912626,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,dexamethasone,DB01234
,195526,DB01017,10073508,56,1413,30,871,0.573358264,1.150617317,0.719351936,1.872827064,0.723267359,DB0101710073508_,0.323976334,0.140298596,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,minocycline,DB01017
,195529,DB01098,10041349,71,8078,61,7148,0.930258761,1.029936401,0.720008666,1.477080681,0.971506676,DB0109810041349_,0.028907138,0.029497054,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,195530,DB01306,10041349,45,4163,35,3831,0.500547376,1.183152842,0.742030333,1.900308667,0.662098371,DB0130610041349_,0.412341138,0.168182776,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,insulin aspart,DB01306
,195541,DB01069,10016288,48,6652,21,2374,0.414088079,0.815733529,0.477988609,1.437522517,0.583373393,DB0106910016288_,0.538927829,-0.203667535,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,promethazine,DB01069
,195575,DB00363,10002855,29,4599,34,6854,0.368101132,1.271117464,0.745954113,2.152998304,0.53781375,DB0036310002855_,0.620242969,0.239896406,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,clozapine,DB00363
,195578,DB01224,10062355,43,8065,17,5900,0.035323482,1.850321273,1.032378326,3.464158953,0.096110732,DB0122410062355_,2.342254296,0.615359285,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,195580,DB00005,10064848,49,128033,27,42392,0.045263292,0.600891391,0.368239569,1,0.116089734,DB0000510064848_,2.15339182,-0.509341075,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,etanercept,DB00005
,195590,DB08889,10003988,66,3099,79,3806,0.932812682,1.026043946,0.725914859,1.446303137,0.973554948,DB0888910003988_,0.026801012,0.025710578,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,carfilzomib,DB08889
,195598,DB08889,10016173,44,3121,33,3852,0.037479645,1.645485001,1.02138369,2.67448805,0.100551412,DB0888910016173_,2.297086116,0.498035174,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,carfilzomib,DB08889
,195609,DB00619,10006002,43,2856,26,2468,0.181094089,1.429067851,0.8555287,2.430271802,0.325222522,DB0061910006002_,1.123245648,0.357022379,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,imatinib,DB00619
,195611,DB00619,10028411,63,2836,53,2441,0.925259339,1.023117664,0.695691669,1.509613682,0.967973417,DB0061910028411_,0.032550654,0.022854499,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,imatinib,DB00619
,195653,DB01076,10011469,50,25697,14,25569,7.02740441432685e-06,3.553246393,1.933485542,6.961258028,7.96873705912775e-05,DB0107610011469_,9.437399447,1.267861663,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,195656,DB00213,10012374,59,18836,14,13407,6.79287531777266e-05,2.999493565,1.65375741,5.820850434,0.000572003,DB0021310012374_,7.466366371,1.098443463,female,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,195659,DB01076,10012374,61,25686,35,25548,0.010312167,1.733464814,1.125357078,2.707980101,0.036464024,DB0107610012374_,3.311429156,0.550122188,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,195665,DB00213,10022998,40,18855,18,13403,0.110970683,1.579633651,0.884513251,2.928657505,0.227542273,DB0021310022998_,1.480419241,0.457192954,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,195689,DB09027,10013968,71,5108,72,7080,0.073173721,1.366755834,0.96868901,1.927995436,0.166807273,DB0902710013968_,1.790916187,0.312439927,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ledipasvir,DB09027
,195690,DB09027,10033371,93,5086,83,7069,0.004297512,1.557260131,1.143150686,2.124556295,0.018108385,DB0902710033371_,4.011380171,0.442927951,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,195716,DB01075,10061623,77,19871,49,11048,0.457641442,0.873701185,0.602373603,1.277812275,0.624945745,DB0107510061623_,0.470090441,-0.135016855,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,195718,DB05676,10027940,124,47005,120,25209,5.70037920046849e-06,0.55415832,0.427460381,0.71870673,6.62837723000727e-05,DB0567610027940_,9.621565452,-0.590304857,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,195720,DB00051,10037876,56,25675,18,11402,0.257844968,1.381650869,0.799718681,2.498314872,0.418736213,DB0005110037876_,0.87051412,0.323279066,NA,10037876,Rash papular,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,195731,DB00563,10019641,31,46615,23,15325,0.004075743,0.443108519,0.250038617,0.79606163,0.017347732,DB0056310019641_,4.054293517,-0.813940575,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,methotrexate,DB00563
,195751,DB00476,10027940,55,17202,16,6161,0.503361355,1.231141861,0.694610135,2.303742021,0.664516372,DB0047610027940_,0.408695764,0.207942081,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,195752,DB00476,10029216,93,17164,9,6168,1.35760562015046e-05,3.713365509,1.872426531,8.377848198,0.000142029,DB0047610029216_,8.859482729,1.311938611,female,10029216,Nervousness,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,195753,DB00476,10033864,37,17220,15,6162,0.640169316,0.88268873,0.47247774,1.732480059,0.777185833,DB0047610033864_,0.25207579,-0.124782655,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,195754,DB00563,10061819,44,46602,27,15321,0.012836505,0.5357883,0.324355045,0.900123765,0.043452437,DB0056310061819_,3.136088342,-0.624016159,NA,10061819,Disease recurrence,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,195759,DB09027,10019211,1311,3868,1627,5525,0.001049384,1.150944818,1.057709523,1.252307775,0.00573631,DB0902710019211_,5.160939116,0.140583186,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ledipasvir,DB09027
,195762,DB01233,10040108,20,3401,54,1672,5.57013616011392e-12,0.182150261,0.102939133,0.310504115,2.22847837090707e-10,DB0123310040108_,22.22453192,-1.702923325,male,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,metoclopramide,DB01233
,195766,DB08880,10010264,109,3229,10,799,0.001356505,2.696731854,1.403238555,5.808716504,0.007080171,DB0888010010264_,4.950457225,0.992040615,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,teriflunomide,DB08880
,195768,DB00480,10064687,39,67389,35,67627,0.643834473,1.118219663,0.69012057,1.818208892,0.780122296,DB0048010064687_,0.248304582,0.111737834,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,195780,DB00373,10012735,60,1772,43,1244,0.919287885,0.979578424,0.646507931,1.495191122,0.964315349,DB0037310012735_,0.036336912,-0.02063298,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,timolol,DB00373
,195789,DB01068,10043554,33,13730,32,6808,0.007959265,0.511344083,0.304510922,0.859705394,0.029670867,DB0106810043554_,3.517589634,-0.670712563,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,clonazepam,DB01068
,195794,DB09068,10053762,95,2300,42,944,0.701519407,0.928387354,0.633662412,1.379941778,0.820770837,DB0906810053762_,0.197511336,-0.074306226,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,vortioxetine,DB09068
,195795,DB08910,10008469,41,16703,32,17456,0.241549644,1.338994054,0.822385767,2.197824048,0.399630677,DB0891010008469_,0.917214465,0.291918626,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,195850,DB00564,10011906,72,2532,46,1417,0.496638663,0.875986534,0.593129955,1.304990554,0.658795476,DB0056410011906_,0.417342147,-0.132404561,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,carbamazepine,DB00564
,195901,DB00497,10076308,143,19124,117,16258,0.802807201,1.039061124,0.807329235,1.339440596,0.893313651,DB0049710076308_,0.112817527,0.03831754,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,195920,DB00661,10028810,43,3485,8,1587,0.014907567,2.447319477,1.133931255,6.041181032,0.04907576,DB0066110028810_,3.014390045,0.894993335,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,verapamil,DB00661
,195950,DB01276,10022067,75,1942,69,1442,0.228713902,0.807156467,0.569904518,1.144562876,0.384312269,DB0127610022067_,0.956299856,-0.214237742,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,195973,DB00904,10076308,131,22938,81,14375,0.943712826,1.013534626,0.761819534,1.355258877,0.982531901,DB0090410076308_,0.017622466,0.013443851,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,195975,DB00126,10001949,37,10134,24,5921,0.691734987,0.900758932,0.524130878,1.575530186,0.814161162,DB0012610001949_,0.205596945,-0.104517613,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,195980,DB01254,10002855,31,3436,21,3127,0.330628957,1.343374124,0.745848488,2.46523622,0.499343952,DB0125410002855_,0.694460138,0.295184452,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,dasatinib,DB01254
,195981,DB09270,10002855,60,3054,22,2346,0.002340634,2.094730625,1.261957907,3.597408665,0.011057432,DB0927010002855_,4.504652475,0.739424965,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ubidecarenone,DB09270
,195991,DB01137,10020993,36,7736,57,5536,0.000189853,0.451990514,0.288826326,0.699111712,0.001379107,DB0113710020993_,6.586318994,-0.794094085,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,levofloxacin,DB01137
,196006,DB00332,10022437,36,2648,23,1633,0.893390552,0.965239408,0.554278902,1.7126864,0.955535825,DB0033210022437_,0.045483023,-0.035379117,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ipratropium,DB00332
,196034,DB00722,10033433,65,25338,21,26011,1.18197123397673e-06,3.17757937,1.916529628,5.474439225,1.66006486161253e-05,DB0072210033433_,11.00606879,1.156119702,female,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,196066,DB00451,10044016,43,47228,11,15408,0.530663521,1.275315671,0.646521598,2.743022041,0.687659764,DB0045110044016_,0.374461092,0.243193733,NA,10044016,Tooth abscess,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,196115,DB08908,10061599,46,10627,6,3273,0.047765904,2.361231248,1.004620819,6.772504929,0.120898101,DB0890810061599_,2.112807233,0.859183198,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,dimethyl fumarate,DB08908
,196312,DB00563,10071408,88,46558,9,15339,0.000143728,3.221455652,1.621337853,7.279824938,0.001087635,DB0056310071408_,6.823749807,1.169833323,female,10071408,Maternal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,196325,DB01048,10012735,13,452,59,1076,0.034087273,0.524707709,0.261304351,0.979645243,0.093585124,DB0104810012735_,2.368883841,-0.644913916,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,abacavir,DB01048
,196326,DB06210,10012735,50,1410,26,1035,0.194082882,1.411431806,0.855438971,2.378986213,0.341806938,DB0621010012735_,1.073509211,0.344604654,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,eltrombopag,DB06210
,196328,DB06210,10019211,77,1383,32,1029,0.007146283,1.789931867,1.160646154,2.817258914,0.027235037,DB0621010019211_,3.603250999,0.582177556,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,eltrombopag,DB06210
,196330,DB06210,10028813,70,1390,25,1036,0.001401562,2.086320548,1.294160521,3.463904376,0.007264849,DB0621010028813_,4.924707735,0.735402011,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,eltrombopag,DB06210
,196334,DB00571,10037660,91,5032,41,2568,0.577635797,1.132665848,0.772617302,1.685496885,0.726593021,DB0057110037660_,0.319388765,0.124574012,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,196343,DB00437,10033775,47,6874,68,11478,0.441702713,1.154090808,0.77736663,1.700770736,0.609894929,DB0043710033775_,0.494468584,0.143312854,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,196358,DB00722,10056819,79,25324,48,25984,0.00431464,1.688698808,1.164551529,2.47131146,0.018164542,DB0072210056819_,4.008283842,0.523958296,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,196362,DB00158,10038428,49,16766,30,8074,0.335735247,0.786596629,0.489006931,1.284494678,0.504909083,DB0015810038428_,0.683376899,-0.240039705,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,folic acid,DB00158
,196376,DB00669,10039906,69,6308,11,1086,1,1.079936656,0.565291971,2.270837625,1,DB0066910039906_,0,0.076902387,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,sumatriptan,DB00669
,196397,DB01060,10037153,70,8517,33,5048,0.306895945,1.25723682,0.81857988,1.966757025,0.473929847,DB0106010037153_,0.746695971,0.228916313,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,amoxicillin,DB01060
,196403,DB00571,10020937,44,5079,16,2593,0.274643608,1.403909274,0.774886462,2.670946334,0.437919142,DB0057110020937_,0.825720994,0.339260684,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,propranolol,DB00571
,196428,DB09037,10003239,56,2470,72,2763,0.47388953,0.870063402,0.599732983,1.25673676,0.639730178,DB0903710003239_,0.446708788,-0.139189195,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pembrolizumab,DB09037
,196429,DB00404,10022081,48,19844,8,9854,0.002475446,2.979350066,1.396453818,7.29521359,0.011575715,DB0040410022081_,4.458845913,1.091705178,female,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,196436,DB00956,10052904,40,5774,18,3449,0.34362326,1.327367358,0.742248964,2.463862232,0.512893885,DB0095610052904_,0.667686306,0.283197551,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocodone,DB00956
,196443,DB01390,10003549,44,1365,37,1480,0.262334317,1.289260058,0.808233019,2.066686651,0.424074879,DB0139010003549_,0.857845238,0.254068455,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sodium bicarbonate,DB01390
,196445,DB00537,10010264,105,7452,49,4249,0.273048443,1.221843933,0.860499717,1.755805045,0.43603149,DB0053710010264_,0.830040813,0.200361139,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,196446,DB00567,10010264,69,4450,25,2056,0.316853845,1.275097915,0.793809103,2.11000802,0.484680264,DB0056710010264_,0.724265855,0.243022972,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,cephalexin,DB00567
,196448,DB00698,10010774,67,3081,8,421,0.858073603,1.144390698,0.543489576,2.778782512,0.932233804,DB0069810010774_,0.070171633,0.134872354,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,nitrofurantoin,DB00698
,196454,DB00335,10062237,32,8434,23,5442,0.680973407,0.897741582,0.508548556,1.608419722,0.807096653,DB0033510062237_,0.21431185,-0.107873023,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,atenolol,DB00335
,196456,DB00136,10069339,66,2026,49,1633,0.703752368,1.085666603,0.734299283,1.614332432,0.822321894,DB0013610069339_,0.195623362,0.082194179,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,calcitriol,DB00136
,196457,DB00335,10069339,110,8356,123,5342,2.51321796597615e-05,0.571776698,0.436969892,0.747377306,0.000242644,DB0033510069339_,8.323913616,-0.559006752,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,atenolol,DB00335
,196458,DB00537,10069339,162,7395,153,4145,5.86498473091784e-06,0.593483164,0.471292502,0.74772512,6.79273512457261e-05,DB0053710069339_,9.597071788,-0.521746433,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ciprofloxacin,DB00537
,196459,DB00567,10069339,72,4447,72,2009,4.34406225365827e-06,0.451818253,0.319889223,0.638163111,5.21863237373892e-05,DB0056710069339_,9.860690095,-0.794475275,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,cephalexin,DB00567
,196460,DB00698,10069339,49,3099,11,418,0.156084355,0.600943987,0.305238477,1.292043838,0.292260339,DB0069810069339_,1.230110303,-0.509253548,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,nitrofurantoin,DB00698
,196461,DB01390,10069339,55,1354,110,1407,8.00327681478894e-05,0.519687351,0.365675263,0.731469228,0.000659352,DB0139010069339_,7.324253615,-0.654527896,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,sodium bicarbonate,DB01390
,196467,DB00065,10010774,34,9430,31,4926,0.02620287,0.572928019,0.341251481,0.965230024,0.076200967,DB0006510010774_,2.574381124,-0.556995192,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,infliximab,DB00065
,196469,DB00993,10010774,31,3218,22,1597,0.240273301,0.699323445,0.390639259,1.272137731,0.398145545,DB0099310010774_,0.920937649,-0.357641919,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,azathioprine,DB00993
,196472,DB08904,10010774,53,11557,10,3549,0.180478389,1.627470774,0.818342268,3.592006254,0.324424314,DB0890410010774_,1.125703008,0.487027137,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,certolizumab pegol,DB08904
,196474,DB00091,10020751,69,5441,17,2653,0.010589087,1.978914556,1.14838116,3.597292245,0.03725278,DB0009110020751_,3.290028699,0.68254849,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,cyclosporine,DB00091
,196478,DB00916,10020751,59,5264,13,2418,0.014798041,2.084557935,1.127651526,4.151023011,0.048798959,DB0091610020751_,3.020046307,0.734556811,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,metronidazole,DB00916
,196500,DB00065,10046571,81,9383,16,4941,0.000142969,2.665709884,1.544393892,4.88944789,0.001082357,DB0006510046571_,6.828614101,0.980470395,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,infliximab,DB00065
,196501,DB00993,10046571,72,3177,12,1607,9.60927319075336e-05,3.034388786,1.628899017,6.163147722,0.00077006,DB0099310046571_,7.169041863,1.110010016,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,azathioprine,DB00993
,196505,DB00502,10012218,39,1355,73,1799,0.098276546,0.709379338,0.465005976,1.067938408,0.208288907,DB0050210012218_,1.568829188,-0.343364864,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,haloperidol,DB00502
,196506,DB00641,10012218,27,14097,32,12443,0.296487622,0.744765488,0.428991728,1.284019673,0.462367337,DB0064110012218_,0.771395602,-0.294685892,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,196507,DB01137,10012218,35,7737,34,5559,0.222399855,0.739654606,0.447399003,1.223951923,0.376491286,DB0113710012218_,0.976860377,-0.301571951,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,levofloxacin,DB01137
,196522,DB06605,10008531,74,13999,54,12979,0.184799023,1.27050861,0.88183001,1.840843311,0.329910844,DB0660510008531_,1.10893283,0.239417301,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,196570,DB08932,10024968,55,19388,13,6584,0.266324558,1.436683631,0.774302056,2.868671032,0.428473676,DB0893210024968_,0.847525977,0.362337423,NA,10024968,Lower respiratory tract infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,196572,DB00404,10049414,31,19861,28,9834,0.025883585,0.548177524,0.317991437,0.94908404,0.075439379,DB0040410049414_,2.584425866,-0.601156096,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,196576,DB08910,10015967,36,16708,28,17460,0.261199278,1.343565012,0.796847976,2.286940001,0.422760038,DB0891010015967_,0.860950547,0.295326538,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,pomalidomide,DB08910
,196586,DB00177,10069339,93,4707,112,2738,3.40044869269815e-07,0.483047084,0.361393684,0.644410872,5.47173516299792e-06,DB0017710069339_,12.11591478,-0.727641148,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,valsartan,DB00177
,196597,DB00264,10007598,31,29576,19,24873,0.320881205,1.372124707,0.750814574,2.571382355,0.48913286,DB0026410007598_,0.71512113,0.31636042,NA,10007598,Cardiac pacemaker insertion,10042613,Surgical and medical procedures,Surg,metoprolol,DB00264
,196600,DB00331,10011781,96,24850,25,20727,2.07919233581319e-08,3.202696578,2.0439725,5.194643292,4.34087136988481e-07,DB0033110011781_,14.65002055,1.163993136,female,10011781,Cystitis,10021881,Infections and infestations,Infec,metformin,DB00331
,196643,DB00316,10029368,43,65431,22,36931,0.796512635,1.103208686,0.645409215,1.936844214,0.889807667,DB0031610029368_,0.116749944,0.098222921,NA,10029368,Neutrophil count increased,10022891,Investigations,Inv,acetaminophen,DB00316
,196646,DB00073,10040070,67,7339,72,6335,0.201009927,0.803268225,0.566168708,1.138278127,0.350202491,DB0007310040070_,1.049243746,-0.219066593,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,rituximab,DB00073
,196647,DB00741,10040070,52,4042,46,3128,0.539137873,0.874832279,0.575245042,1.33420629,0.694958144,DB0074110040070_,0.363903659,-0.133723092,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,hydrocortisone,DB00741
,196675,DB00958,10051792,55,4539,16,2569,0.017900695,1.945406314,1.095853171,3.645281888,0.056651588,DB0095810051792_,2.870835267,0.665470857,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,carboplatin,DB00958
,196682,DB00480,10039906,156,67272,159,67503,0.910239929,0.984499425,0.784090889,1.23596357,0.95957874,DB0048010039906_,0.041260903,-0.015621965,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,196687,DB00043,10047895,35,6378,20,2280,0.12325965,0.625625272,0.350477901,1.14625009,0.246017144,DB0004310047895_,1.402354053,-0.469003693,NA,10047895,Weight decreased,10022891,Investigations,Inv,omalizumab,DB00043
,196714,DB00051,10003553,79,25652,26,11394,0.204259954,1.34954622,0.856317731,2.192072404,0.354188929,DB0005110003553_,1.03792481,0.299768402,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,196726,DB00338,10016326,62,33612,28,22244,0.105697988,1.465376101,0.923401257,2.379321275,0.219678313,DB0033810016326_,1.515591017,0.382111934,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,196741,DB01015,10020642,41,9846,44,9337,0.58811525,0.883653087,0.562535105,1.385413917,0.735074148,DB0101510020642_,0.307783903,-0.123690729,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,196816,DB00051,10069339,48,25683,44,11376,0.000619113,0.483202798,0.314065619,0.745135007,0.003696395,DB0005110069339_,5.600397153,-0.727318841,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,adalimumab,DB00051
,196817,DB00338,10069339,714,32960,642,21630,1.32727862531924e-08,0.729866858,0.654224188,0.814389848,2.89883827723443e-07,DB0033810069339_,15.05378559,-0.314893147,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,196819,DB00542,10069339,30,1656,50,1374,0.002922759,0.497943487,0.303896779,0.803542263,0.013228536,DB0054210069339_,4.325378977,-0.697268689,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,benazepril,DB00542
,196845,DB00175,10037423,41,8090,38,6068,0.363250263,0.809294126,0.506999047,1.294752095,0.53278462,DB0017510037423_,0.629638027,-0.211592861,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,196871,DB00246,10013709,76,998,53,648,0.709087809,0.931107997,0.637504104,1.368044819,0.826380878,DB0024610013709_,0.190699501,-0.071380007,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ziprasidone,DB00246
,196904,DB00399,10005750,47,6945,23,4975,0.145438532,1.46378454,0.869871458,2.529369082,0.277650556,DB0039910005750_,1.28139195,0.381025233,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,zoledronic acid,DB00399
,196908,DB14500,10017885,51,7758,17,4056,0.123925234,1.568390404,0.88946687,2.900820236,0.246976631,DB1450010017885_,1.398461557,0.450049873,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,196909,DB00126,10022004,79,10092,28,5917,0.020775414,1.654171634,1.061243951,2.647905816,0.06368539,DB0012610022004_,2.753800102,0.50330036,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,196911,DB11089,10022004,57,10118,17,8390,9.04822800348138e-05,2.780082773,1.592827401,5.101506336,0.000732807,DB1108910022004_,7.218627514,1.022480702,female,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,196912,DB14500,10022004,49,7760,17,4056,0.154327967,1.506500923,0.851231194,2.794014055,0.289937147,DB1450010022004_,1.238091116,0.409789692,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,196913,DB01296,10025482,39,1410,21,962,0.426028824,1.266951091,0.722021096,2.282056298,0.594773566,DB0129610025482_,0.519574506,0.236613298,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,glucosamine,DB01296
,196914,DB00231,10028411,45,3251,13,2126,0.009610776,2.263371242,1.196389784,4.584557959,0.034487269,DB0023110028411_,3.367165047,0.816855402,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,temazepam,DB00231
,196936,DB00264,10012374,58,29549,31,24861,0.042964957,1.574118657,1.000632284,2.520034914,0.111610802,DB0026410012374_,2.192737441,0.453695533,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,196939,DB00678,10012374,44,15555,23,10701,0.320315325,1.31605657,0.777132562,2.284842888,0.488511072,DB0067810012374_,0.716393142,0.274639818,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,losartan,DB00678
,196946,DB00207,10014387,59,9021,80,5375,2.25692998688444e-06,0.439447367,0.307939195,0.624020749,2.94790612995111e-05,DB0020710014387_,10.43183033,-0.822237326,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,azithromycin,DB00207
,196947,DB00264,10014387,83,29524,64,24828,0.619809497,1.0906287,0.777353314,1.536181766,0.760441282,DB0026410014387_,0.273856379,0.086754319,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,metoprolol,DB00264
,196954,DB00571,10016173,135,4988,56,2553,0.21498259,1.233799493,0.893619645,1.72295976,0.367380697,DB0057110016173_,1.001356647,0.210098427,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,propranolol,DB00571
,196964,DB00207,10020772,55,9025,44,5411,0.175484815,0.749478466,0.494263914,1.142337827,0.317960267,DB0020710020772_,1.145828849,-0.288377692,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,azithromycin,DB00207
,196972,DB09140,10027175,55,3686,16,1782,0.074990221,1.661724408,0.935162954,3.116245182,0.169806853,DB0914010027175_,1.773093647,0.507855863,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,oxygen,DB09140
,196994,DB00331,10061394,42,24904,16,20736,0.007771455,2.185590664,1.202901452,4.165780223,0.029098673,DB0033110061394_,3.537062715,0.781886119,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,197013,DB00999,10016970,42,21388,9,12230,0.005173957,2.668398404,1.279779451,6.236820788,0.021021323,DB0099910016970_,3.862217952,0.981478444,NA,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,197026,DB01075,10029148,37,19911,18,11079,0.675671713,1.14374702,0.634541371,2.135198547,0.803403192,DB0107510029148_,0.218898584,0.134309732,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,diphenhydramine,DB01075
,197064,DB00706,10068319,7,1068,57,15868,0.123522228,1.824506226,0.700312478,4.021252666,0.246435048,DB0070610068319_,1.400656817,0.601309389,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tamsulosin,DB00706
,197116,DB00099,10069339,35,2350,31,1924,0.803542251,0.92438278,0.551362099,1.556385422,0.893716343,DB0009910069339_,0.112366844,-0.078629029,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,filgrastim,DB00099
,197117,DB00370,10069339,68,4473,89,3574,0.002614,0.610531102,0.437156539,0.849425541,0.01208389,DB0037010069339_,4.415882114,-0.493426042,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,mirtazapine,DB00370
,197118,DB00864,10069339,257,6612,420,7972,0.000170492,0.737781282,0.627036619,0.866796397,0.001260582,DB0086410069339_,6.676181673,-0.304107864,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,tacrolimus,DB00864
,197119,DB00996,10069339,431,38522,456,21969,1.27447798707553e-19,0.53901885,0.470951939,0.616893393,1.27861274390383e-17,DB0099610069339_,38.89817088,-0.618004737,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,197121,DB01073,10069339,27,1038,65,1585,0.050751673,0.634383149,0.386523025,1.015745926,0.126398306,DB0107310069339_,2.068317201,-0.455102171,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,fludarabine,DB01073
,197122,DB09020,10069339,46,1908,56,1548,0.044039965,0.666527483,0.438520376,1.008630148,0.113661984,DB0902010069339_,2.174526291,-0.405673905,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,bisacodyl,DB09020
,197162,DB00646,10029331,51,3402,27,1973,0.813058645,1.095461046,0.671730324,1.823213682,0.89954571,DB0064610029331_,0.10586541,0.091175322,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,nystatin,DB00646
,197169,DB00204,10014387,32,932,79,964,3.32537390502189e-05,0.419141276,0.266170011,0.646591181,0.000310616,DB0020410014387_,8.076951869,-0.869547241,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,dofetilide,DB00204
,197171,DB04868,10008479,25,1616,48,1468,0.002805421,0.473239465,0.278101559,0.787470048,0.012794392,DB0486810008479_,4.358748319,-0.74815375,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,nilotinib,DB04868
,197173,DB00203,10022687,46,13832,23,8915,0.387390554,1.289016287,0.764817699,2.22965873,0.557475061,DB0020310022687_,0.584337511,0.25387936,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,sildenafil,DB00203
,197178,DB00722,10022687,41,25362,33,25999,0.352104357,1.273619923,0.785417395,2.079664993,0.521853004,DB0072210022687_,0.650369332,0.241863179,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,197182,DB09053,10011224,45,2240,65,3987,0.316468986,1.232185891,0.820304192,1.836901067,0.484161998,DB0905310011224_,0.725335721,0.208789739,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibrutinib,DB09053
,197206,DB01068,10005557,58,13705,37,6803,0.231577868,0.778156279,0.505903826,1.210418336,0.387832065,DB0106810005557_,0.947182854,-0.250827902,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,clonazepam,DB01068
,197214,DB05676,10022004,123,47006,64,25265,0.878100798,1.032979017,0.757291376,1.420650334,0.948386386,DB0567610022004_,0.05299328,0.032446877,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,197242,DB01065,10001488,18,4313,38,3013,9.58771618988472e-05,0.330958089,0.177421829,0.595629219,0.000768567,DB0106510001488_,7.170982813,-1.105763532,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,melatonin,DB01065
,197257,DB01018,10016256,19,393,31,748,0.649269049,1.166379233,0.614040201,2.162656329,0.784176674,DB0101810016256_,0.243120935,0.153904278,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,guanfacine,DB01018
,197274,DB00557,10022998,35,5952,18,3049,1,0.996070366,0.548011206,1.871459393,1,DB0055710022998_,0,-0.003937376,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,hydroxyzine,DB00557
,197353,DB00182,10061422,15,5179,45,2807,5.4000232031087e-10,0.180706274,0.093386435,0.330977278,1.57798343406017e-08,DB0018210061422_,17.96453302,-1.710882362,male,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,197354,DB00734,10061422,48,4002,58,4844,1,1.001705889,0.667180938,1.497887631,1,DB0073410061422_,0,0.001704435,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,197416,DB00334,10013710,115,2734,93,2719,0.157643401,1.229727574,0.922417115,1.642974157,0.294314709,DB0033410013710_,1.223105644,0.20679266,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,olanzapine,DB00334
,197444,DB00635,10038540,30,33023,57,23737,1.00024977770236e-05,0.378322046,0.234610715,0.598899655,0.00010862,DB0063510038540_,9.127651415,-0.972009472,NA,10038540,Renal tubular necrosis,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,197459,DB05679,10037162,126,6805,68,4841,0.077579328,1.318130537,0.971420618,1.801631925,0.174255582,DB0567910037162_,1.747232193,0.276214473,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,ustekinumab,DB05679
,197460,DB00051,10049414,36,25695,16,11404,1,0.998595883,0.539938103,1.928226218,1,DB0005110049414_,0,-0.001405104,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,197472,DB09079,10012735,174,483,170,707,0.001043383,1.49776734,1.168510301,1.920383684,0.005708259,DB0907910012735_,5.165841157,0.403975559,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,nintedanib,DB09079
,197476,DB01060,10002424,18,8569,47,5034,1.52351086536944e-08,0.225013921,0.122826411,0.395327698,3.27972834531004e-07,DB0106010002424_,14.93033505,-1.491593006,male,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,amoxicillin,DB01060
,197492,DB00316,10074300,55,65419,22,36931,0.192114637,1.411320755,0.846492719,2.430900485,0.339318185,DB0031610074300_,1.080817012,0.344525972,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,197512,DB01306,10064355,29,4179,40,3826,0.115053554,0.663798073,0.396006102,1.100217167,0.233681001,DB0130610064355_,1.453798338,-0.409777283,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin aspart,DB01306
,197535,DB00451,10005839,48,47223,18,15401,0.667721108,0.869711408,0.496514699,1.58920075,0.798169392,DB0045110005839_,0.225434433,-0.139593837,NA,10005839,Blood triglycerides increased,10022891,Investigations,Inv,levothyroxine,DB00451
,197564,DB00904,10028622,21,23048,30,14426,0.003707074,0.438143348,0.238305715,0.791513134,0.016042217,DB0090410028622_,4.132531441,-0.825209143,NA,10028622,Myoclonus,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,197581,DB00502,10007515,31,1363,21,1851,0.015751382,2.004311798,1.109961884,3.687129119,0.051228046,DB0050210007515_,2.971468122,0.695300759,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,haloperidol,DB00502
,197582,DB01183,10007515,18,541,34,514,0.022521941,0.503298871,0.264041459,0.929927144,0.067774522,DB0118310007515_,2.691568938,-0.686571109,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,naloxone,DB01183
,197583,DB00186,10014387,77,16824,53,9955,0.413519901,0.859670416,0.597546307,1.244963315,0.582916818,DB0018610014387_,0.539710782,-0.151206201,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,lorazepam,DB00186
,197596,DB01050,10039906,161,17947,104,9267,0.07887144,0.799379732,0.619981734,1.034368206,0.176452108,DB0105010039906_,1.734705784,-0.223919187,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,197602,DB00182,10019063,23,5171,35,2817,0.000144942,0.358039121,0.201554076,0.62471701,0.001095478,DB0018210019063_,6.816564738,-1.027113023,male,10019063,Hallucination,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,197605,DB00612,10011906,30,1110,29,611,0.03804754,0.569592198,0.326920069,0.993730758,0.101711627,DB0061210011906_,2.285613652,-0.562834617,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,bisoprolol,DB00612
,197606,DB00612,10053762,33,1107,19,621,1,0.974323655,0.532844855,1.83004037,1,DB0061210053762_,0,-0.026011736,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,bisoprolol,DB00612
,197607,DB00627,10053762,40,1289,35,1564,0.195941121,1.386509486,0.853118543,2.26265404,0.344226198,DB0062710053762_,1.066456285,0.326789427,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,niacin,DB00627
,197625,DB11065,10061471,32,3154,20,2668,0.328840743,1.353385133,0.748644949,2.503061605,0.497465311,DB1106510061471_,0.698229451,0.30260896,NA,10061471,Pseudomonas infection,10021881,Infections and infestations,Infec,pancrelipase amylase,DB11065
,197663,DB00584,10069339,34,2047,58,1816,0.002910916,0.520144847,0.328590627,0.812028315,0.013180607,DB0058410069339_,4.329008674,-0.653647954,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,enalapril,DB00584
,197664,DB01306,10069339,96,4112,144,3722,0.000137173,0.603480775,0.459365832,0.789931321,0.001044495,DB0130610069339_,6.864222086,-0.505041095,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,insulin aspart,DB01306
,197665,DB01307,10069339,57,2467,53,2016,0.560803618,0.878887428,0.591005949,1.308877613,0.713366432,DB0130710069339_,0.337760061,-0.129098457,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,insulin detemir,DB01307
,197667,DB06655,10069339,26,3662,59,2060,7.9775708258174e-10,0.247963233,0.14954402,0.401048354,2.25959535729106e-08,DB0665510069339_,17.60549499,-1.3944748,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,liraglutide,DB06655
,197670,DB00184,10013654,31,1263,28,954,0.508196981,0.836343906,0.481729804,1.457880241,0.66876728,DB0018410013654_,0.402319143,-0.17871538,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,nicotine,DB00184
,197695,DB00813,10005734,37,10535,32,10136,0.718024672,1.112445458,0.673691413,1.846250209,0.833497656,DB0081310005734_,0.18212439,0.106560707,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,fentanyl,DB00813
,197698,DB09153,10005734,38,7761,30,5669,0.805871318,0.925238867,0.557469396,1.548365704,0.894977506,DB0915310005734_,0.110956695,-0.077703341,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,sodium chloride,DB09153
,197716,DB00005,10013050,143,127939,73,42346,0.003451778,0.648371696,0.485621292,0.871974383,0.015149649,DB0000510013050_,4.189777915,-0.433291142,NA,10013050,Disability,10041244,Social circumstances,SocCi,etanercept,DB00005
,197718,DB00007,10017577,20,1927,49,4403,0.895526662,0.932622566,0.523616265,1.6033029,0.95615204,DB0000710017577_,0.044838341,-0.069754698,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,leuprolide,DB00007
,197746,DB00007,10069327,19,1928,39,4413,0.669969525,1.115079065,0.60698532,1.982596582,0.799758272,DB0000710069327_,0.223445757,0.108925312,NA,10069327,Product quality issue,10077536,Product issues,Prod,leuprolide,DB00007
,197759,DB00104,10013709,85,1396,56,1021,0.598935399,1.110114826,0.774936803,1.600476453,0.7436826,DB0010410013709_,0.296140948,0.104463457,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,octreotide,DB00104
,197786,DB00104,10076309,34,1447,21,1056,0.583577671,1.181470397,0.661932368,2.155427028,0.731559476,DB0010410076309_,0.312576755,0.166759762,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,octreotide,DB00104
,197789,DB00572,10076309,53,2849,23,2103,0.035062216,1.700786701,1.020719685,2.917403918,0.09552346,DB0057210076309_,2.348383402,0.531090909,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,atropine,DB00572
,197790,DB00761,10076309,104,15203,53,8572,0.616929727,1.10640392,0.786486479,1.572451096,0.758040539,DB0076110076309_,0.277018414,0.101115045,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,197793,DB00958,10076309,32,4562,27,2558,0.133879166,0.664564917,0.384757642,1.155910084,0.261153494,DB0095810076309_,1.342646943,-0.408622712,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,carboplatin,DB00958
,197797,DB00656,10039906,124,11889,73,6546,0.653946065,0.935258062,0.693671021,1.268668746,0.787852518,DB0065610039906_,0.238444366,-0.066932786,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,trazodone,DB00656
,197798,DB00959,10039906,76,8002,36,4966,0.204476849,1.310118446,0.868663822,2.008988299,0.354472754,DB0095910039906_,1.037123794,0.27011755,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,197810,DB05676,10016825,38,47091,21,25308,0.892355805,0.972467514,0.556258644,1.744550184,0.955096839,DB0567610016825_,0.045942542,-0.027918609,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,apremilast,DB05676
,197813,DB11750,10028813,258,2242,105,1408,0.000271498,1.542951526,1.212526338,1.974298797,0.001859522,DB1175010028813_,6.287435761,0.433697157,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,clobetasol,DB11750
,197814,DB01261,10037153,37,3744,21,3282,0.11471073,1.544393192,0.878643481,2.78297605,0.233200938,DB0126110037153_,1.455854803,0.434631077,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,sitagliptin,DB01261
,197817,DB00007,10054112,18,1929,34,4418,0.545351263,1.212446389,0.642961763,2.214451175,0.70010051,DB0000710054112_,0.356531368,0.192640128,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,leuprolide,DB00007
,197823,DB01018,10069326,37,375,92,687,0.142462152,0.736964602,0.478821359,1.115489351,0.27325251,DB0101810069326_,1.297358965,-0.305215418,NA,10069326,Product substitution issue,10077536,Product issues,Prod,guanfacine,DB01018
,197826,DB13961,10037884,62,9395,29,6385,0.107988718,1.452940222,0.919510843,2.34528905,0.223054769,DB1396110037884_,1.500337937,0.373589242,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,fish oil,DB13961
,197844,DB00169,10014184,47,38644,14,18161,0.168686176,1.577699505,0.853662077,3.103843629,0.309091401,DB0016910014184_,1.174118251,0.455967776,NA,10014184,Eczema,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,197846,DB00169,10040831,92,38599,27,18148,0.030289828,1.602040388,1.033076589,2.561006976,0.085314218,DB0016910040831_,2.461414161,0.471278059,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,197847,DB06643,10040831,92,52329,7,7508,0.12661379,1.885677582,0.878902921,4.822633705,0.250936359,DB0664310040831_,1.382555921,0.634287216,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,197924,DB01238,10022116,45,5205,24,3478,0.391052414,1.252842206,0.745669715,2.154160236,0.560886866,DB0123810022116_,0.578236059,0.225414735,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole,DB01238
,197953,DB00230,10003285,155,19519,37,8614,0.000509615,1.848710867,1.28325139,2.725304544,0.003135693,DB0023010003285_,5.764905088,0.614488568,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,197972,DB00207,10019303,37,9043,18,5437,0.489252869,1.235824453,0.685210579,2.308428354,0.65261027,DB0020710019303_,0.426775158,0.21173832,NA,10019303,Heart rate increased,10022891,Investigations,Inv,azithromycin,DB00207
,197973,DB00381,10019303,196,29164,88,22799,1.08662989942073e-05,1.741145581,1.346387589,2.266627685,0.00011658,DB0038110019303_,9.056933984,0.554543276,NA,10019303,Heart rate increased,10022891,Investigations,Inv,amlodipine,DB00381
,197990,DB08906,10047895,36,2157,21,1137,0.778954293,0.903666511,0.510720844,1.637399293,0.879558975,DB0890610047895_,0.128334662,-0.101294891,NA,10047895,Weight decreased,10022891,Investigations,Inv,fluticasone furoate,DB08906
,197993,DB08906,10061428,36,2157,17,1141,0.772138393,1.120138759,0.609946767,2.136602702,0.875252473,DB0890610061428_,0.133242894,0.11345257,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,fluticasone furoate,DB08906
,198000,DB00008,10013786,31,1494,22,1654,0.12728542,1.559767496,0.870118839,2.840899947,0.251849694,DB0000810013786_,1.378922822,0.444536769,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,peginterferon alfa-2a,DB00008
,198001,DB00811,10013786,35,2763,32,4124,0.045969363,1.6323436,0.978990156,2.730373236,0.117425141,DB0081110013786_,2.141954249,0.490016774,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,ribavirin,DB00811
,198005,DB06605,10016807,253,13820,147,12886,5.23469873036984e-06,1.604736987,1.302435091,1.982931447,6.15908935218313e-05,DB0660510016807_,9.694996531,0.472959872,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,apixaban,DB06605
,198015,DB00512,10048302,43,4694,99,4999,1.93646032747858e-05,0.462623059,0.314851957,0.669750713,0.000194126,DB0051210048302_,8.547002683,-0.770842684,NA,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,vancomycin,DB00512
,198048,DB01225,10037400,38,5006,18,4622,0.021854666,1.949035881,1.083631934,3.633312299,0.066287781,DB0122510037400_,2.7137497,0.66733483,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enoxaparin,DB01225
,198059,DB00115,10013916,37,18388,16,10456,0.393858486,1.314950331,0.713294941,2.533280429,0.563819421,DB0011510013916_,0.573021254,0.273798894,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,198072,DB00581,10037844,50,2063,44,2025,0.604106666,1.115402525,0.725228917,1.72076919,0.747555739,DB0058110037844_,0.290946409,0.109215349,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,lactulose,DB00581
,198143,DB00410,10011224,38,1567,26,983,0.795139271,0.91687442,0.538542868,1.583384539,0.889069071,DB0041010011224_,0.117580351,-0.086784763,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mupirocin,DB00410
,198197,DB00181,10013950,75,9781,28,5843,0.032143608,1.60008667,1.022743956,2.569173299,0.089406851,DB0018110013950_,2.41455797,0.470057797,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,baclofen,DB00181
,198199,DB00448,10013950,43,5102,26,3098,1,1.004236171,0.601863283,1.706190244,1,DB0044810013950_,0,0.004227224,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,lansoprazole,DB00448
,198202,DB00829,10013950,52,8000,15,4439,0.028797881,1.923475481,1.064929337,3.683151092,0.082032219,DB0082910013950_,2.500643189,0.654133696,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,diazepam,DB00829
,198205,DB09153,10013950,44,7755,29,5670,0.722245049,1.109339779,0.677749782,1.84104735,0.836398842,DB0915310013950_,0.178649696,0.103765045,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,198277,DB00904,10017888,51,23018,35,14421,0.739488074,0.912917628,0.581931731,1.447139595,0.85016024,DB0090410017888_,0.16233043,-0.091109623,NA,10017888,Gastroenteritis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,198381,DB00207,10021143,62,9018,64,5391,0.002946818,0.579171114,0.401032961,0.835860727,0.013307639,DB0020710021143_,4.319417034,-0.546157312,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,198462,DB01068,10027417,26,13737,32,6808,0.000665899,0.402688546,0.230266581,0.698033692,0.003931967,DB0106810027417_,5.538615557,-0.909591855,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,clonazepam,DB01068
,198489,DB00207,10028735,55,9025,16,5439,0.009430633,2.071544981,1.168430512,3.877541705,0.033962663,DB0020710028735_,3.382493514,0.728294696,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,198504,DB00181,10028810,95,9761,28,5843,0.000694846,2.03090166,1.318471459,3.220156602,0.004066356,DB0018110028810_,5.505007926,0.708479862,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,baclofen,DB00181
,198506,DB00575,10028810,57,5187,26,3803,0.044875178,1.607270274,0.992105098,2.668318508,0.115347551,DB0057510028810_,2.159805527,0.474537258,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,clonidine,DB00575
,198511,DB00904,10028810,294,22775,93,14363,1.62143869504818e-09,1.993621608,1.572270657,2.547543961,4.32027532684658e-08,DB0090410028810_,16.95736161,0.689952888,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,198514,DB01202,10028810,39,6675,21,5697,0.092421897,1.584978794,0.908557682,2.839453774,0.19908294,DB0120210028810_,1.614033758,0.460571028,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,levetiracetam,DB01202
,198515,DB09153,10028810,129,7670,92,5607,0.890884194,1.025031375,0.776599368,1.357472544,0.954700385,DB0915310028810_,0.04635772,0.024723222,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,198520,DB00741,10029354,48,4046,74,3100,0.000203821,0.497029302,0.337189749,0.726729991,0.001463777,DB0074110029354_,6.526735009,-0.699106296,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,hydrocortisone,DB00741
,198524,DB09153,10029354,52,7747,63,5636,0.007689622,0.60051882,0.407084758,0.88249617,0.028862162,DB0915310029354_,3.545223805,-0.509961298,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,sodium chloride,DB09153
,198583,DB00169,10037876,50,38641,18,18157,0.364725798,1.305194126,0.748091714,2.377933861,0.534352466,DB0016910037876_,0.626699609,0.266351786,NA,10037876,Rash papular,10040785,Skin and subcutaneous tissue disorders,Skin,cholecalciferol,DB00169
,198649,DB00829,10043071,55,7997,23,4431,0.286822602,1.324953946,0.799608327,2.262226449,0.451607049,DB0082910043071_,0.794942839,0.281377701,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,diazepam,DB00829
,198810,DB00410,10053762,47,1558,28,981,0.904367982,1.056902658,0.643425639,1.765293832,0.957497529,DB0041010053762_,0.043432138,0.05534261,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,mupirocin,DB00410
,198932,DB00169,10061598,34,38657,21,18154,0.315003498,0.760308833,0.428622155,1.379073291,0.48255191,DB0016910061598_,0.728666778,-0.274030569,NA,10061598,Immunodeficiency,10021428,Immune system disorders,Immun,cholecalciferol,DB00169
,199025,DB01075,10064687,37,19911,19,11078,0.889195773,1.083474124,0.606971391,1.995502285,0.953968782,DB0107510064687_,0.047124331,0.08017266,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,199042,DB00904,10065553,44,23025,27,14429,1,1.021234905,0.618183574,1.715991077,1,DB0090410065553_,0,0.021012586,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,ondansetron,DB00904
,199135,DB00327,10062355,47,6091,26,4236,0.403620769,1.257136239,0.761388094,2.118217432,0.573344154,DB0032710062355_,0.556269124,0.228836308,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,hydromorphone,DB00327
,199143,DB00480,10033433,75,67353,59,67603,0.16739713,1.275899304,0.894933332,1.826457401,0.307415186,DB0048010033433_,1.179556048,0.243651267,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,199149,DB00169,10041834,32,38659,49,18126,1.37984119271978e-07,0.306207112,0.189707484,0.488032122,2.43580428143984e-06,DB0016910041834_,12.92523356,-1.183493568,male,10041834,Squamous cell carcinoma of skin,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cholecalciferol,DB00169
,199185,DB00635,10019301,37,33016,18,23776,0.21804545,1.480267518,0.821439049,2.762705071,0.371223827,DB0063510019301_,0.990950092,0.392222827,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,prednisone,DB00635
,199216,DB00480,10016766,256,67172,190,67472,0.001716612,1.353377929,1.117054237,1.642029143,0.008573276,DB0048010016766_,4.759105344,0.302603637,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,199241,DB00126,10044034,38,10133,16,5929,0.32310465,1.389627882,0.7558217,2.672043762,0.491507227,DB0012610044034_,0.710278636,0.329036,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,199242,DB00471,10044034,37,14152,17,5448,0.544645824,0.837892974,0.459712457,1.588263738,0.699553641,DB0047110044034_,0.357312803,-0.176864903,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,199243,DB00588,10044034,42,16482,22,8446,1,0.97827701,0.570437772,1.721904163,1,DB0058810044034_,0,-0.021962408,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,199249,DB14500,10044034,36,7773,17,4056,0.774115005,1.104987882,0.603932168,2.100620557,0.876749952,DB1450010044034_,0.131533444,0.099834368,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,199250,DB00158,10013538,81,16734,19,8085,0.003644728,2.059684465,1.237019581,3.598865407,0.015828447,DB0015810013538_,4.145946535,0.722552799,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,folic acid,DB00158
,199252,DB05676,10013538,76,47053,14,25315,5.51422745787965e-05,2.920585802,1.637911971,5.594356259,0.000480177,DB0567610013538_,7.641355487,1.071784213,female,10013538,Diverticulitis,10021881,Infections and infestations,Infec,apremilast,DB05676
,199299,DB01012,10005703,107,10525,83,8602,0.769551083,1.053626558,0.782406143,1.422933392,0.873802333,DB0101210005703_,0.134901093,0.052238078,NA,10005703,Blood parathyroid hormone increased,10022891,Investigations,Inv,cinacalcet,DB01012
,199308,DB00186,10006784,67,16834,28,9980,0.136412475,1.418582313,0.899382936,2.292416135,0.264688437,DB0018610006784_,1.329201855,0.349658002,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,199310,DB00697,10008531,70,6026,15,1791,0.298919723,1.386921535,0.783877803,2.61551477,0.464889943,DB0069710008531_,0.765954583,0.327086568,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,199311,DB09270,10008531,40,3074,26,2342,0.617401222,1.172070472,0.695617313,2.0066952,0.758406913,DB0927010008531_,0.276535213,0.158771819,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,199312,DB00697,10048334,56,6040,14,1792,0.668530476,1.18672768,0.650121185,2.314020797,0.798578634,DB0069710048334_,0.224921839,0.17119967,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,tizanidine,DB00697
,199342,DB06403,10017918,64,21407,7,6654,0.004736231,2.841916819,1.301820377,7.355294716,0.019579999,DB0640310017918_,3.933246717,1.044478761,female,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,199363,DB01015,10011831,27,9860,47,9334,0.013868216,0.543843116,0.325427723,0.89213616,0.046203948,DB0101510011831_,3.074690022,-0.609094464,NA,10011831,Cytomegalovirus infection,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,199395,DB00421,10038695,142,8761,72,5180,0.318331612,1.166110468,0.870176693,1.574136009,0.48631812,DB0042110038695_,0.720892301,0.153673825,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,199403,DB00836,10043554,50,5485,46,4029,0.299553714,0.798447294,0.523044806,1.221265361,0.465545402,DB0083610043554_,0.764545653,-0.225086319,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,loperamide,DB00836
,199453,DB00108,10069339,38,10156,18,3277,0.21099895,0.681206132,0.378730607,1.269839673,0.36249068,DB0010810069339_,1.014756516,-0.383890328,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,natalizumab,DB00108
,199479,DB01073,10019211,31,1034,42,1608,0.627201922,1.147767546,0.69272649,1.883322312,0.766648183,DB0107310019211_,0.265727276,0.137818791,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,fludarabine,DB01073
,199481,DB00196,10054236,33,5050,22,3263,0.890934723,0.969193242,0.547280301,1.748230377,0.954720579,DB0019610054236_,0.046336569,-0.031291263,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,fluconazole,DB00196
,199524,DB14500,10008531,75,7734,30,4043,0.255802746,1.306891612,0.843632498,2.071480037,0.416539164,DB1450010008531_,0.87577479,0.267651503,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,199527,DB00820,10040070,58,11857,17,5799,0.064712632,1.668575845,0.957180449,3.059499875,0.151950161,DB0082010040070_,1.884202698,0.511970475,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,tadalafil,DB00820
,199550,DB00264,10015916,60,29547,25,24867,0.003033553,2.019798402,1.246937368,3.362879699,0.013641907,DB0026410015916_,4.294608849,0.702997705,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,metoprolol,DB00264
,199573,DB00316,10030041,95,65379,42,36911,0.212571325,1.277025331,0.879055785,1.883126829,0.364526044,DB0031610030041_,1.009157278,0.244533414,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,acetaminophen,DB00316
,199574,DB00381,10030041,64,29296,26,22861,0.004022525,1.920809912,1.199833833,3.158611026,0.017161511,DB0038110030041_,4.065086107,0.652746926,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,amlodipine,DB00381
,199617,DB01076,10003983,49,25698,38,25545,0.28341254,1.281787065,0.821708338,2.013134467,0.447766942,DB0107610003983_,0.803482401,0.248255249,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,199643,DB08932,10019301,78,19365,24,6573,0.733190636,1.103132138,0.689780274,1.824943041,0.845185329,DB0893210019301_,0.168199352,0.098153531,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,macitentan,DB08932
,199645,DB00215,10001949,56,11047,18,5258,0.170193863,1.480751195,0.856541475,2.679230849,0.311105789,DB0021510001949_,1.167622266,0.392549523,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,199662,DB08868,10042772,53,9149,9,2502,0.215448166,1.610366939,0.786071606,3.718660797,0.36794588,DB0886810042772_,0.999819416,0.476462065,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,199682,DB00635,10025650,30,33023,41,23753,0.007829501,0.526324912,0.317242476,0.86400399,0.029270149,DB0063510025650_,3.531187072,-0.641836554,NA,10025650,Malignant melanoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,199693,DB00958,10046571,82,4512,21,2564,0.000844577,2.218712151,1.356533797,3.783398903,0.004788032,DB0095810046571_,5.341635708,0.796926915,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,carboplatin,DB00958
,199694,DB01229,10046571,99,5642,17,2692,2.12261071731068e-05,2.778342938,1.64629102,4.97012171,0.000210103,DB0122910046571_,8.46791319,1.021854685,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,paclitaxel,DB01229
,199728,DB06643,10065612,89,52332,9,7506,0.362714263,1.418359386,0.71406929,3.204570125,0.532250908,DB0664310065612_,0.630640268,0.349500842,NA,10065612,Loose tooth,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,199729,DB00343,10025082,50,8686,16,5079,0.039898647,1.827219878,1.022064878,3.441378386,0.105501327,DB0034310025082_,2.249031752,0.602795619,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,199730,DB00343,10038428,41,8695,9,5086,0.004952317,2.664527763,1.274305944,6.24038253,0.020318899,DB0034310038428_,3.896203845,0.980026842,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,diltiazem,DB00343
,199731,DB00471,10038428,30,14159,21,5444,0.041025593,0.549311755,0.30389977,1.010365719,0.107706523,DB0047110038428_,2.228345129,-0.599089139,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,montelukast,DB00471
,199732,DB00343,10061024,89,8647,51,5044,1,1.017956276,0.712219712,1.468520816,1,DB0034310061024_,0,0.017796966,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,diltiazem,DB00343
,199789,DB00115,10039906,126,18299,70,10402,0.940596374,1.023203457,0.757210851,1.392210998,0.979869437,DB0011510039906_,0.020335944,0.02293835,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,199790,DB00390,10039906,35,4110,26,3275,0.897174452,1.072674241,0.626037055,1.859721233,0.956338178,DB0039010039906_,0.044643686,0.070154821,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,digoxin,DB00390
,199791,DB00814,10039906,61,8226,25,3390,1,1.005543705,0.620656941,1.674751017,1,DB0081410039906_,0,0.005528395,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,199792,DB01076,10039906,160,25587,200,25383,0.030147165,0.793627205,0.640089748,0.982678071,0.085023417,DB0107610039906_,2.464828568,-0.231141443,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,199793,DB01409,10039906,39,5992,22,3944,0.601760929,1.16677256,0.673739218,2.069503064,0.746010424,DB0140910039906_,0.293015705,0.154241441,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,tiotropium,DB01409
,199797,DB00814,10049848,60,8227,24,3391,1,1.030468804,0.630927511,1.733272459,1,DB0081410049848_,0,0.030013849,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,199798,DB01222,10049848,44,9230,21,5384,0.51995984,1.222211009,0.710455945,2.166472302,0.679112765,DB0122210049848_,0.386968091,0.200661521,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,199838,DB00996,10035742,43,38910,35,22390,0.127752569,0.706986247,0.441813567,1.138285983,0.252469927,DB0099610035742_,1.376463137,-0.346744066,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,199861,DB01211,10016256,66,1586,44,743,0.094377824,0.702801033,0.467674421,1.064865035,0.202342667,DB0121110016256_,1.597792649,-0.352681453,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,clarithromycin,DB01211
,199863,DB00199,10037087,51,2659,12,688,0.875503475,1.099631366,0.574409935,2.278879089,0.94649511,DB0019910037087_,0.054989475,0.094975001,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,erythromycin,DB00199
,199903,DB00635,10019948,35,33018,36,23758,0.148504315,0.699575832,0.426409759,1.146668124,0.281928129,DB0063510019948_,1.266103101,-0.357281082,NA,10019948,Herpes simplex,10021881,Infections and infestations,Infec,prednisone,DB00635
,199907,DB00059,10040070,29,798,50,1057,0.29686612,0.768348879,0.464297111,1.250752322,0.462695363,DB0005910040070_,0.770686404,-0.26351138,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,pegaspargase,DB00059
,199934,DB05676,10020642,118,47011,38,25291,0.005388992,1.670559469,1.149761499,2.47658964,0.021712086,DB0567610020642_,3.829886206,0.513158581,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,199945,DB00374,10012374,46,17670,14,5710,1,1.061747989,0.573036797,2.092834178,1,DB0037410012374_,0,0.059916596,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,treprostinil,DB00374
,199952,DB00319,10069339,151,1241,239,1614,0.080911177,0.821745233,0.656833922,1.025736946,0.179912891,DB0031910069339_,1.715282487,-0.196324868,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,piperacillin,DB00319
,199962,DB00316,10023215,36,65438,20,36933,1,1.015914515,0.572500398,1.852532844,1,DB0031610023215_,0,0.015789207,NA,10023215,Joint effusion,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,199988,DB00048,10013709,25,209,191,658,2.99693480734687e-05,0.412371153,0.252950549,0.648894847,0.000283616,DB0004810013709_,8.167888238,-0.885831478,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,collagenase clostridium histolyticum,DB00048
,199993,DB00335,10003285,43,8423,15,5450,0.042563455,1.854762342,1.008974383,3.598163736,0.110830692,DB0033510003285_,2.199751543,0.61775657,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,199995,DB00736,10003285,51,10540,19,5534,0.210345603,1.409309537,0.81689103,2.53045567,0.361605699,DB0073610003285_,1.017200889,0.343099895,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,esomeprazole,DB00736
,199999,DB01076,10003285,104,25643,66,25517,0.004372115,1.567992487,1.140293989,2.169280085,0.0183492,DB0107610003285_,3.998169326,0.44979613,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,200048,DB00572,10010264,47,2855,22,2104,0.086093273,1.574261224,0.926752186,2.752149906,0.188501598,DB0057210010264_,1.668648796,0.453786098,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,atropine,DB00572
,200145,DB01012,10005393,33,10599,25,8660,0.793335063,1.078535909,0.621568965,1.89337406,0.887941952,DB0101210005393_,0.118848907,0.075604482,NA,10005393,Blood calcium abnormal,10022891,Investigations,Inv,cinacalcet,DB01012
,200146,DB01012,10005700,64,10568,64,8621,0.28472774,0.815776476,0.567052557,1.173564669,0.449250775,DB0101210005700_,0.800174028,-0.203614888,NA,10005700,Blood parathyroid hormone abnormal,10022891,Investigations,Inv,cinacalcet,DB01012
,200177,DB00737,10020937,56,2745,8,924,0.019198873,2.35597148,1.111550313,5.744150639,0.059862677,DB0073710020937_,2.815702057,0.85695316,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,meclizine,DB00737
,200194,DB01068,10039117,42,13721,13,6827,0.152096842,1.607462597,0.845784949,3.266322997,0.28686295,DB0106810039117_,1.248750704,0.474656909,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,200195,DB00455,10042209,52,9349,10,5108,0.001218165,2.840943208,1.426726169,6.275300957,0.006476431,DB0045510042209_,5.039585652,1.044136113,female,10042209,Stress,10037175,Psychiatric disorders,Psych,loratadine,DB00455
,200198,DB00181,10042609,39,9817,17,5854,0.333148122,1.367984841,0.755144629,2.581405868,0.502196386,DB0018110042609_,0.688764029,0.313338738,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,baclofen,DB00181
,200201,DB00471,10042609,67,14122,8,5457,0.000429593,3.236347758,1.55002851,7.805665437,0.00271962,DB0047110042609_,5.907263023,1.174445459,female,10042609,Surgery,10042613,Surgical and medical procedures,Surg,montelukast,DB00471
,200205,DB01050,10042609,94,18014,21,9350,0.000232236,2.323263103,1.434814583,3.929663926,0.001632234,DB0105010042609_,6.41780594,0.842972707,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,ibuprofen,DB01050
,200206,DB01373,10042609,83,22637,11,7370,0.002550206,2.456660632,1.303438591,5.112949427,0.01184209,DB0137310042609_,4.436095124,0.898802961,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,calcium,DB01373
,200208,DB00471,10048393,60,14129,6,5459,0.000282789,3.863706748,1.673486401,10.95043914,0.001924929,DB0047110048393_,6.252866183,1.35162702,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,200209,DB00737,10048393,51,2750,6,926,0.00852842,2.861740827,1.222472826,8.18703408,0.031352379,DB0073710048393_,3.462465138,1.05143012,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,meclizine,DB00737
,200210,DB00737,10048959,73,2728,19,913,0.393455341,1.285769808,0.762713617,2.269297942,0.563365036,DB0073710048959_,0.573827485,0.251357611,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,meclizine,DB00737
,200240,DB00455,10062244,47,9354,23,5095,0.708827803,1.113060439,0.661576708,1.922864965,0.826268961,DB0045510062244_,0.19083494,0.107113374,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,200261,DB00904,10021328,44,23025,34,14422,0.354299079,0.810600269,0.50613309,1.308384965,0.524123492,DB0090410021328_,0.64602795,-0.209980232,NA,10021328,Ileus,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,200265,DB00678,10001551,45,15554,26,10698,0.545932388,1.190386397,0.718294834,2.011221016,0.70064122,DB0067810001551_,0.355759335,0.174277957,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,losartan,DB00678
,200266,DB00678,10003481,46,15553,27,10697,0.552496661,1.171730972,0.712758876,1.961513391,0.706341183,DB0067810003481_,0.347656896,0.158482119,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,losartan,DB00678
,200271,DB00956,10003246,40,5774,10,3457,0.01197799,2.394674104,1.174934727,5.377190285,0.041093972,DB0095610003246_,3.191893843,0.873247148,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocodone,DB00956
,200272,DB00956,10076309,49,5765,20,3447,0.169845024,1.464842875,0.853106644,2.606273725,0.310705811,DB0095610076309_,1.168908759,0.381747984,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocodone,DB00956
,200273,DB00999,10076309,161,21269,71,12168,0.074783829,1.29729556,0.974407948,1.74185314,0.169499856,DB0099910076309_,1.774903204,0.260281759,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,200284,DB00264,10014062,36,29571,36,24856,0.479296362,0.840558021,0.514475912,1.373308474,0.644364554,DB0026410014062_,0.439490635,-0.173689298,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,200285,DB00331,10014062,43,24903,24,20728,0.140158113,1.491276858,0.884565911,2.570148521,0.270086132,DB0033110014062_,1.309014363,0.399632705,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,metformin,DB00331
,200295,DB00188,10069339,104,7782,154,8674,0.027731392,0.752746996,0.580104482,0.973570149,0.079639043,DB0018810069339_,2.530250817,-0.284026102,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,bortezomib,DB00188
,200296,DB00399,10069339,96,6896,81,4917,0.282559583,0.84507878,0.620690326,1.153013005,0.446660971,DB0039910069339_,0.805955426,-0.168325425,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,zoledronic acid,DB00399
,200297,DB00480,10069339,319,67109,421,67241,0.000223199,0.759214021,0.65407083,0.880547835,0.001579666,DB0048010069339_,6.450541955,-0.275471564,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,200298,DB00005,10044044,44,128038,11,42408,0.532225245,1.324840068,0.673216464,2.844989626,0.68905507,DB0000510044044_,0.372434084,0.281291749,NA,10044044,Tooth loss,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,200311,DB00669,10022052,80,6297,8,1089,0.171192444,1.729285003,0.833451086,4.154667624,0.312474803,DB0066910022052_,1.163231444,0.54770803,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,200313,DB00814,10027599,70,8217,14,3401,0.010993725,2.06938182,1.15307005,3.984314767,0.038393685,DB0081410027599_,3.259862294,0.727249925,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,200315,DB00381,10018304,35,29325,19,22868,0.21890635,1.436484833,0.799265437,2.658929976,0.37220735,DB0038110018304_,0.988304188,0.362199041,NA,10018304,Glaucoma,10015919,Eye disorders,Eye,amlodipine,DB00381
,200325,DB00381,10069868,60,29300,19,22868,0.000371726,2.464583478,1.450019928,4.37455986,0.002411652,DB0038110069868_,6.027443282,0.902022819,NA,10069868,Device issue,10077536,Product issues,Prod,amlodipine,DB00381
,200350,DB01015,10071066,38,9849,13,9368,0.001049897,2.77995612,1.447600595,5.691776137,0.005738523,DB0101510071066_,5.160553483,1.022435144,female,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,200358,DB00999,10022000,229,21201,83,12156,0.00029615,1.581925524,1.224208585,2.061124484,0.00199623,DB0099910022000_,6.216495025,0.458642791,NA,10022000,Influenza,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,200363,DB00285,10006451,90,10861,8,3710,2.04928436910123e-05,3.842763169,1.866429181,9.180546208,0.000203997,DB0028510006451_,8.49740468,1.346191683,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,venlafaxine,DB00285
,200367,DB00285,10074903,90,10861,37,3681,0.356143694,0.824386058,0.555253639,1.246218088,0.525838337,DB0028510074903_,0.642761458,-0.193116342,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,200372,DB00959,10007515,56,8022,47,4955,0.127380667,0.73598956,0.489623587,1.110553563,0.251924369,DB0095910007515_,1.378626359,-0.306539345,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,methylprednisolone,DB00959
,200375,DB00126,10061024,53,10118,55,5890,0.003504341,0.561010018,0.376765436,0.834609873,0.015335319,DB0012610061024_,4.17759665,-0.578016516,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,ascorbic acid,DB00126
,200403,DB00331,10064848,119,24827,76,20676,0.071896086,1.303985016,0.969116726,1.763601658,0.164594228,DB0033110064848_,1.804272057,0.265424972,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,metformin,DB00331
,200404,DB00678,10064848,128,15471,79,10645,0.47797952,1.114857342,0.83473633,1.496683589,0.643286259,DB0067810064848_,0.441165461,0.108726453,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,losartan,DB00678
,200405,DB01136,10064848,105,9779,107,11008,0.489630805,1.104630946,0.834569858,1.461846022,0.65297307,DB0113610064848_,0.426219391,0.099511294,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,carvedilol,DB01136
,200410,DB00165,10039906,30,2115,28,1338,0.173845381,0.677909147,0.389427147,1.183388379,0.31594592,DB0016510039906_,1.15218422,-0.388742002,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,pyridoxine,DB00165
,200421,DB06209,10028596,19,445,34,623,0.475583464,0.782520999,0.415868185,1.43257257,0.64116317,DB0620910028596_,0.444471299,-0.245234521,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,prasugrel,DB06209
,200422,DB00230,10035528,56,19618,60,8591,2.26234166307111e-06,0.40873173,0.27856557,0.598945787,2.95334743550157e-05,DB0023010035528_,10.42998621,-0.894696255,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,pregabalin,DB00230
,200424,DB00575,10035528,39,5205,21,3808,0.294881758,1.358647814,0.778430788,2.435184515,0.460791094,DB0057510035528_,0.774810497,0.30648995,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,clonidine,DB00575
,200457,DB01015,10006002,39,9848,32,9349,0.55455129,1.15698621,0.705694647,1.909527629,0.708072508,DB0101510006002_,0.345208778,0.145818529,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfamethoxazole,DB01015
,200461,DB00246,10019211,43,1031,12,689,0.007235088,2.393627721,1.229093556,5.023239299,0.027477864,DB0024610019211_,3.59437455,0.87281009,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ziprasidone,DB00246
,200466,DB01015,10022004,49,9838,31,9350,0.092141858,1.502201924,0.938036203,2.439348148,0.198650652,DB0101510022004_,1.616207515,0.406931981,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,200481,DB00213,10049414,40,18855,37,13384,0.24910101,0.767407581,0.478093409,1.234757508,0.408498615,DB0021310049414_,0.895266755,-0.264737222,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,200510,DB00471,10058080,60,14129,26,5439,0.629874523,0.888367735,0.551392909,1.468309799,0.768905704,DB0047110058080_,0.262786939,-0.118369506,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,montelukast,DB00471
,200541,DB00455,10064355,83,9318,40,5078,0.570206827,1.13081345,0.765179964,1.695661726,0.720856239,DB0045510064355_,0.327315553,0.122937241,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,200542,DB00476,10064355,74,17183,29,6148,0.655355018,0.912990402,0.586274246,1.456726516,0.78898945,DB0047610064355_,0.23700233,-0.091029911,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,200545,DB00213,10065154,153,18742,98,13323,0.440827827,1.109842239,0.854776875,1.446681856,0.609127528,DB0021310065154_,0.495727628,0.104217878,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,pantoprazole,DB00213
,200547,DB00455,10065154,40,9361,24,5094,0.69599947,0.906962901,0.532868267,1.574740063,0.817040153,DB0045510065154_,0.202067039,-0.097653732,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,loratadine,DB00455
,200550,DB01050,10065154,100,18008,31,9340,0.012318268,1.673062535,1.107411218,2.592922118,0.042025528,DB0105010065154_,3.169478029,0.5146558,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,ibuprofen,DB01050
,200553,DB13867,10065154,38,4512,17,2537,0.482815546,1.25685209,0.690760515,2.379795102,0.647065147,DB1386710065154_,0.435308299,0.228610254,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,fluticasone,DB13867
,200561,DB01076,10073085,47,25700,49,25534,0.838633983,0.952973484,0.624645018,1.452513415,0.917160508,DB0107610073085_,0.086472786,-0.048168199,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,200606,DB06643,10005703,105,52316,26,7489,0.016659237,0.57811102,0.373078939,0.926276909,0.053528273,DB0664310005703_,2.927545304,-0.547989353,NA,10005703,Blood parathyroid hormone increased,10022891,Investigations,Inv,denosumab,DB06643
,200609,DB06724,10009033,56,7873,14,3905,0.021216436,1.98389536,1.088317476,3.864321294,0.064800607,DB0672410009033_,2.736440311,0.685062265,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,200620,DB13867,10046571,127,4423,28,2526,1.06478237431702e-06,2.590073994,1.703799708,4.064061661,1.51203699129784e-05,DB1386710046571_,11.09946772,0.951686444,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,fluticasone,DB13867
,200622,DB01409,10062355,57,5974,30,3936,0.37868642,1.251785237,0.789406397,2.021766448,0.548689138,DB0140910062355_,0.600223232,0.224570722,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,tiotropium,DB01409
,200623,DB01592,10062355,50,6226,14,3053,0.06240132,1.751202109,0.951277299,3.436102824,0.147940713,DB0159210062355_,1.910943672,0.560302472,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,200635,DB00264,10020583,27,29580,33,24859,0.155310025,0.687610706,0.397614494,1.179587064,0.291240922,DB0026410020583_,1.233604443,-0.374532436,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,200637,DB00381,10020583,50,29310,49,22838,0.265722869,0.795098066,0.525114629,1.204446342,0.427802997,DB0038110020583_,0.849092478,-0.229289819,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,200642,DB00381,10037032,22,29338,30,22857,0.049993643,0.571350149,0.313928731,1.024480198,0.124990052,DB0038110037032_,2.079521131,-0.559753036,NA,10037032,Proteinuria,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,200694,DB00471,10005734,37,14152,14,5451,1,1.017969084,0.537020704,2.040109808,1,DB0047110005734_,0,0.017809548,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,montelukast,DB00471
,200695,DB00588,10048334,54,16470,9,8459,0.000722112,3.08148968,1.507980409,7.102954865,0.00420206,DB0058810048334_,5.472180498,1.125413142,female,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,200697,DB00338,10033664,67,33607,24,22248,0.009737471,1.848073479,1.143622182,3.081948061,0.034842014,DB0033810033664_,3.35693132,0.614143734,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,200704,DB06643,10003983,66,52355,6,7509,0.372206163,1.577660295,0.687160046,4.455467891,0.541853673,DB0664310003983_,0.61275929,0.455942924,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,200720,DB00404,10015090,100,19792,40,9822,0.280333114,1.240610158,0.851024135,1.839466137,0.444184061,DB0040410015090_,0.811516252,0.215603321,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,200731,DB14500,10037087,173,7636,50,4023,0.000113728,1.822805302,1.320258621,2.555842172,0.000891001,DB1450010037087_,7.023164521,0.600376689,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,potassium,DB14500
,200734,DB00555,10037153,62,6985,20,3466,0.099612166,1.538180967,0.914687136,2.693278808,0.210170636,DB0055510037153_,1.559835527,0.430600528,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,lamotrigine,DB00555
,200735,DB00586,10037153,103,7006,31,2774,0.209247884,1.315498443,0.870661906,2.039468948,0.360306625,DB0058610037153_,1.020799875,0.274215638,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,diclofenac,DB00586
,200741,DB00196,10010264,100,4983,57,3228,0.459115394,1.136511137,0.810211854,1.607344254,0.626498187,DB0019610010264_,0.467609399,0.127963163,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,fluconazole,DB00196
,200744,DB00958,10020751,56,4538,11,2574,0.00049725,2.887257985,1.493348486,6.124132003,0.003077877,DB0095810020751_,5.783515309,1.060307258,female,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,carboplatin,DB00958
,200749,DB00541,10051398,48,3086,66,4231,1,0.997113421,0.670725775,1.472831902,1,DB0054110051398_,0,-0.002890753,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,vincristine,DB00541
,200759,DB01060,10046306,115,8472,61,5020,0.530262707,1.117093669,0.81027321,1.552973209,0.687343685,DB0106010046306_,0.374920842,0.110730374,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,200760,DB01098,10046306,58,8091,31,7178,0.024895477,1.659786115,1.054112932,2.659485832,0.073261481,DB0109810046306_,2.6137203,0.506688748,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,rosuvastatin,DB01098
,200768,DB00316,10036495,94,65380,27,36926,0.00124262,1.966293735,1.269824144,3.139493327,0.006580391,DB0031610036495_,5.023661132,0.676150418,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,200772,DB00230,10043417,214,19460,87,8564,0.571453352,1.082496784,0.838734845,1.407258807,0.721626297,DB0023010043417_,0.326247869,0.07927021,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,200773,DB00316,10043417,138,65336,53,36900,0.015822966,1.470535138,1.063714961,2.059313421,0.051408092,DB0031610043417_,2.967959683,0.385626374,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,200780,DB00973,10022000,33,3818,21,3000,0.493267649,1.234714567,0.691762339,2.250679463,0.656001425,DB0097310022000_,0.421592318,0.210839824,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ezetimibe,DB00973
,200804,DB00008,10029366,22,1503,31,1645,0.406929177,0.77678828,0.426487953,1.392465799,0.576440054,DB0000810029366_,0.550883927,-0.252587449,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,peginterferon alfa-2a,DB00008
,200809,DB08910,10020583,28,16716,33,17455,0.701192258,0.88599915,0.515563284,1.512738942,0.820515905,DB0891010020583_,0.197821984,-0.121039288,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,pomalidomide,DB08910
,200810,DB01377,10035226,63,3733,35,2635,0.301280864,1.270513267,0.824858629,1.985492998,0.467579932,DB0137710035226_,0.760184968,0.239420966,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,magnesium oxide,DB01377
,200811,DB08910,10048294,32,16712,29,17459,0.609761412,1.152764809,0.675113914,1.975995153,0.752071471,DB0891010048294_,0.284923919,0.142163239,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,pomalidomide,DB08910
,200812,DB01234,10066901,94,31531,87,32801,0.456919838,1.12397566,0.830338586,1.522894903,0.624287256,DB0123410066901_,0.47114467,0.116872097,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,200869,DB00188,10044390,30,7856,22,8806,0.163566157,1.528484006,0.851877164,2.783405507,0.302206195,DB0018810044390_,1.19664573,0.424276398,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,200870,DB00455,10044390,31,9370,22,5096,0.387507974,0.766388095,0.429143404,1.39069469,0.557541016,DB0045510044390_,0.584219207,-0.266066586,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,200889,DB01222,10067482,50,9224,14,5391,0.013186896,2.087238649,1.134730691,4.092534627,0.044392617,DB0122210067482_,3.11468211,0.735841972,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,200892,DB00571,10010144,483,4640,239,2370,0.740919712,1.032234943,0.875069602,1.219980705,0.851332166,DB0057110010144_,0.160952902,0.031726299,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,propranolol,DB00571
,200893,DB00571,10038669,77,5046,22,2587,0.013817417,1.794269482,1.102070191,3.035080651,0.046066821,DB0057110038669_,3.077662314,0.584597965,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,propranolol,DB00571
,200894,DB00571,10045555,23,5100,31,2578,0.000416801,0.375091787,0.20838302,0.66604819,0.002650767,DB0057110045555_,5.932906435,-0.980584519,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,propranolol,DB00571
,200905,DB00563,10028997,42,46604,24,15324,0.032618905,0.575429055,0.340394929,0.993790929,0.090460849,DB0056310028997_,2.402838132,-0.552639334,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,methotrexate,DB00563
,200916,DB00047,10037153,64,9221,33,8485,0.007737453,1.784532065,1.153627272,2.807587854,0.029012171,DB0004710037153_,3.540039837,0.579156233,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,insulin glargine,DB00047
,200918,DB00047,10076309,164,9121,139,8379,0.523561993,1.083834489,0.857613865,1.371419809,0.681717293,DB0004710076309_,0.383140234,0.080505206,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,200920,DB05679,10076309,219,6712,161,4748,0.711447351,0.962206142,0.77873582,1.190973846,0.828037267,DB0567910076309_,0.188697118,-0.038526566,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ustekinumab,DB05679
,200925,DB09140,10005750,39,3702,15,1783,0.55946652,1.252157706,0.672771484,2.451936236,0.712186759,DB0914010005750_,0.339415101,0.224868228,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,oxygen,DB09140
,200937,DB08889,10012174,26,3139,55,3830,0.024085472,0.576834906,0.346352679,0.938129145,0.071438348,DB0888910012174_,2.638920463,-0.550199178,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,carfilzomib,DB08889
,200945,DB01017,10013573,53,1416,11,890,0.000356135,3.027181103,1.55223592,6.462526291,0.002326869,DB0101710013573_,6.063231548,1.107631857,female,10013573,Dizziness,10029205,Nervous system disorders,Nerv,minocycline,DB01017
,200954,DB01281,10050584,50,8882,6,1792,0.282306223,1.68122645,0.718972123,4.805424453,0.446367357,DB0128110050584_,0.806612995,0.519523557,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,abatacept,DB01281
,200957,DB06605,10022437,167,13906,95,12938,0.000112151,1.635490895,1.262258598,2.12929377,0.000880228,DB0660510022437_,7.035329634,0.491943001,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,apixaban,DB06605
,200984,DB06186,10037087,24,2185,62,3584,0.072282004,0.63499152,0.377806785,1.035760389,0.165261818,DB0618610037087_,1.80022429,-0.454143634,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ipilimumab,DB06186
,200999,DB00490,10017577,62,4008,23,1553,0.903721597,1.04446704,0.635321945,1.773127165,0.957417047,DB0049010017577_,0.043516196,0.043506746,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,201030,DB00165,10030124,35,2110,18,1348,0.481952627,1.242137898,0.681479802,2.339859541,0.646382366,DB0016510030124_,0.436364052,0.216834006,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,pyridoxine,DB00165
,201049,DB06292,10047700,45,1312,38,1195,0.823389973,1.078608264,0.679477363,1.720033776,0.906247631,DB0629210047700_,0.098442687,0.075671566,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dapagliflozin,DB06292
,201069,DB01276,10022086,130,1887,102,1409,0.73175857,0.951702264,0.721712264,1.257608109,0.844108311,DB0127610022086_,0.169474462,-0.049503041,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,201073,DB01104,10017412,36,15427,16,7270,1,1.060312976,0.57317421,2.047908429,1,DB0110410017412_,0,0.058564125,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,sertraline,DB01104
,201077,DB00341,10038153,40,11365,13,5055,0.373140107,1.368601727,0.71629808,2.791491588,0.542852509,DB0034110038153_,0.610917619,0.313789581,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,cetirizine,DB00341
,201078,DB01104,10038153,61,15402,27,7259,0.820114132,1.064790662,0.665916185,1.744241553,0.904243317,DB0110410038153_,0.100656799,0.062778218,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,sertraline,DB01104
,201087,DB00112,10033775,75,5858,39,4052,0.179427896,1.330161791,0.889735932,2.016448203,0.32317554,DB0011210033775_,1.129559636,0.285300582,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,bevacizumab,DB00112
,201088,DB01101,10033775,134,7455,65,3843,0.762747382,1.0627071,0.782353543,1.455941866,0.868590891,DB0110110033775_,0.140883046,0.060819521,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,capecitabine,DB01101
,201090,DB06605,10035528,91,13982,105,12928,0.131936838,0.801343932,0.597824379,1.072409872,0.258542497,DB0660510035528_,1.352695199,-0.221465046,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,apixaban,DB06605
,201107,DB01611,10066901,316,11597,65,2296,0.779833285,0.962496212,0.73193762,1.282057228,0.880132524,DB0161110066901_,0.127682787,-0.038225148,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,201108,DB05676,10066901,120,47009,80,25249,0.13787208,0.805682181,0.60186194,1.083385234,0.266752612,DB0567610066901_,1.321433596,-0.216065931,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,201116,DB00958,10069339,96,4498,71,2514,0.086471578,0.755767028,0.548035603,1.046324336,0.189147456,DB0095810069339_,1.665228377,-0.280022114,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,carboplatin,DB00958
,201117,DB01248,10069339,31,2669,25,1349,0.088361568,0.626795264,0.356573065,1.112109731,0.192521869,DB0124810069339_,1.647545526,-0.467135325,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,docetaxel,DB01248
,201126,DB00355,10010264,41,1752,29,1234,1,0.995789133,0.600274997,1.671230942,1,DB0035510010264_,0,-0.004219758,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,aztreonam,DB00355
,201129,DB11065,10011224,123,3063,95,2593,0.533379849,1.096016498,0.827313354,1.45574125,0.690141984,DB1106510011224_,0.370857929,0.091682242,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pancrelipase amylase,DB11065
,201134,DB11065,10011762,120,3066,119,2569,0.208309711,0.844967214,0.646529195,1.104366796,0.359185302,DB1106510011762_,1.023916861,-0.168457452,NA,10011762,Cystic fibrosis,10010331,"Congenital, familial and genetic disorders",Cong,pancrelipase amylase,DB11065
,201144,DB11065,10028810,46,3140,41,2647,0.828794964,0.945837134,0.605143468,1.482675595,0.910035117,DB1106510028810_,0.094272091,-0.055684888,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,pancrelipase amylase,DB11065
,201145,DB00003,10061922,68,2930,72,2521,0.230607643,0.812642174,0.572077407,1.153301902,0.386625966,DB0000310061922_,0.950297549,-0.207464397,NA,10061922,Pulmonary function test decreased,10022891,Investigations,Inv,dornase alfa,DB00003
,201150,DB09153,10061922,33,7766,42,5657,0.018610863,0.572376025,0.351005437,0.926228188,0.05838245,DB0915310061922_,2.840739956,-0.557959117,NA,10061922,Pulmonary function test decreased,10022891,Investigations,Inv,sodium chloride,DB09153
,201151,DB11065,10061922,49,3137,47,2641,0.537027864,0.877732841,0.574048098,1.343361561,0.693241204,DB1106510061922_,0.366377283,-0.130413013,NA,10061922,Pulmonary function test decreased,10022891,Investigations,Inv,pancrelipase amylase,DB11065
,201178,DB00182,10076309,52,5142,32,2820,0.646839491,0.891206598,0.561507188,1.434294166,0.782237168,DB0018210076309_,0.2455973,-0.115179006,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,amphetamine,DB00182
,201179,DB01255,10076309,45,2088,32,1546,0.907636225,1.041212024,0.643860819,1.701489879,0.958771936,DB0125510076309_,0.042102046,0.040385442,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lisdexamfetamine,DB01255
,201181,DB08875,10037660,20,623,44,1199,0.688611447,0.874845359,0.484010475,1.531361277,0.812303462,DB0887510037660_,0.207881287,-0.133708141,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,cabozantinib,DB08875
,201186,DB01104,10051118,37,15426,20,7266,0.670050473,0.871405991,0.492423417,1.58567329,0.799758272,DB0110410051118_,0.223445757,-0.137647291,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,201202,DB00338,10039117,81,33593,49,22223,0.654564644,1.093575921,0.757378457,1.59332739,0.788326766,DB0033810039117_,0.237842598,0.089452988,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,201205,DB06643,10039117,93,52328,16,7499,0.469848688,0.832980313,0.486550703,1.518244577,0.63615385,DB0664310039117_,0.452314842,-0.182745271,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,201207,DB00829,10038669,116,7936,76,4378,0.255012861,0.842032811,0.623595462,1.142590346,0.41573277,DB0082910038669_,0.877712604,-0.171936298,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diazepam,DB00829
,201252,DB00338,10041834,28,33646,38,22234,0.003697789,0.486919753,0.287709485,0.814851404,0.01601786,DB0033810041834_,4.134050906,-0.719655948,NA,10041834,Squamous cell carcinoma of skin,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,omeprazole,DB00338
,201386,DB01104,10037423,60,15403,26,7260,0.817036931,1.08769434,0.675288425,1.797410974,0.902121998,DB0110410037423_,0.103005515,0.084060172,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,201398,DB00316,10061598,48,65426,26,36927,0.904243885,1.04198717,0.633527087,1.750010262,0.957497529,DB0031610061598_,0.043432138,0.04112963,NA,10061598,Immunodeficiency,10021428,Immune system disorders,Immun,acetaminophen,DB00316
,201414,DB00956,10069339,72,5742,63,3404,0.031078963,0.677568433,0.475057557,0.968471454,0.08708528,DB0095610069339_,2.44086741,-0.389244723,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,hydrocodone,DB00956
,201415,DB01098,10069339,123,8026,222,6987,5.67034184028824e-11,0.482348068,0.382837494,0.605429185,1.92813629071121e-09,DB0109810069339_,20.06671195,-0.729089292,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,rosuvastatin,DB01098
,201416,DB01104,10069339,145,15318,89,7197,0.048894273,0.765448499,0.582980786,1.009783753,0.122907854,DB0110410069339_,2.096320362,-0.267293344,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,sertraline,DB01104
,201417,DB01233,10069339,60,3361,55,1671,0.001340777,0.54241652,0.368044377,0.800804413,0.007007821,DB0123310069339_,4.960728536,-0.611721086,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,metoclopramide,DB01233
,201418,DB01409,10069339,60,5971,65,3901,0.005610786,0.603119757,0.416393757,0.872274232,0.022437167,DB0140910069339_,3.797036439,-0.5056395,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,tiotropium,DB01409
,201446,DB00182,10033295,63,5131,58,2794,0.005264582,0.591489811,0.40614328,0.862809657,0.021308829,DB0018210033295_,3.848633766,-0.525110821,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,amphetamine,DB00182
,201466,DB00669,10037660,82,6295,18,1079,0.321471202,0.78087774,0.462412179,1.388209153,0.489768386,DB0066910037660_,0.713822682,-0.247336685,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,201470,DB00295,10052904,37,14626,18,9584,0.335602144,1.346930257,0.747143819,2.514589145,0.504766672,DB0029510052904_,0.683658992,0.297828119,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,201487,DB00482,10022000,87,8172,22,3049,0.105471474,1.475349256,0.913758939,2.479087477,0.219330893,DB0048210022000_,1.51717376,0.388894745,NA,10022000,Influenza,10021881,Infections and infestations,Infec,celecoxib,DB00482
,201488,DB00557,10022000,44,5943,18,3049,0.501173328,1.254024631,0.708541628,2.310166455,0.662635947,DB0055710022000_,0.41152954,0.226358084,NA,10022000,Influenza,10021881,Infections and infestations,Infec,hydroxyzine,DB00557
,201510,DB00734,10042458,52,3998,62,4840,1,1.015347484,0.686822698,1.495847156,1,DB0073410042458_,0,0.015230902,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,201530,DB00273,10013887,48,8433,6,2187,0.092173763,2.074546286,0.884953693,5.939124088,0.198694991,DB0027310013887_,1.61598434,0.729742473,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,201540,DB00476,10013954,1112,16145,362,5815,0.105682695,1.106382282,0.977943331,1.253898442,0.219663897,DB0047610013954_,1.515656643,0.101095487,NA,10013954,Dysphoria,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,201547,DB00115,10013990,59,18366,34,10438,1,0.986220167,0.635588576,1.552430796,1,DB0011510013990_,0,-0.013875656,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,cyanocobalamin,DB00115
,201551,DB00273,10015150,46,8435,6,2187,0.122114763,1.987643368,0.845249642,5.702450856,0.244471347,DB0027310015150_,1.408657168,0.6869497,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,topiramate,DB00273
,201565,DB06204,10016256,34,778,18,361,0.650335202,0.876570254,0.473930371,1.672324016,0.785013468,DB0620410016256_,0.242054405,-0.131738425,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tapentadol,DB06204
,201581,DB00425,10017944,63,12632,20,7464,0.016252107,1.861218841,1.109255014,3.253212711,0.052489602,DB0042510017944_,2.947140184,0.621231564,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,zolpidem,DB00425
,201582,DB00476,10017944,68,17189,16,6161,0.137674798,1.523232883,0.873242322,2.816365369,0.266459176,DB0047610017944_,1.322534232,0.420834973,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,201583,DB00497,10017944,55,19212,46,16329,1,1.016230508,0.673995136,1.538400349,1,DB0049710017944_,0,0.016100202,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,201584,DB00656,10017944,52,11961,16,6603,0.041882749,1.794091531,1.007345942,3.369502992,0.109486629,DB0065610017944_,2.211952842,0.584498783,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,201591,DB00181,10042458,64,9792,25,5846,0.078554363,1.528326676,0.947773489,2.536119154,0.175920364,DB0018110042458_,1.737723864,0.424173461,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,201635,DB00425,10061422,27,12668,46,7438,8.1512312100047e-06,0.344649278,0.205808199,0.566713192,9.09402004902265e-05,DB0042510061422_,9.305308405,-1.065227966,male,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,201682,DB00019,10064355,203,18809,92,9437,0.456567137,1.107065353,0.860031119,1.434020763,0.623932241,DB0001910064355_,0.471713505,0.101712688,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,201715,DB00788,10007882,52,9304,32,5029,0.567920291,0.878358177,0.554062223,1.412031768,0.718960885,DB0078810007882_,0.329948324,-0.129700822,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,naproxen,DB00788
,201717,DB00795,10013573,81,4488,23,1480,0.568755624,1.161327172,0.720210644,1.941639738,0.719758387,DB0079510013573_,0.328839697,0.149563465,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sulfasalazine,DB00795
,201734,DB00502,10013983,28,1366,55,1817,0.115104603,0.677251855,0.411294806,1.092863985,0.233775653,DB0050210013983_,1.453393373,-0.389712059,NA,10013983,Dystonia,10029205,Nervous system disorders,Nerv,haloperidol,DB00502
,201769,DB00541,10073755,6,3128,49,4248,6.37216604642e-07,0.166322073,0.058153622,0.389300955,9.59841745158451e-06,DB0054110073755_,11.55391232,-1.793829172,male,10073755,Pneumocystis jirovecii pneumonia,10021881,Infections and infestations,Infec,vincristine,DB00541
,201770,DB00997,10073755,91,5240,42,3472,0.060470115,1.435566238,0.982789733,2.127171693,0.14425348,DB0099710073755_,1.936183249,0.361559363,NA,10073755,Pneumocystis jirovecii pneumonia,10021881,Infections and infestations,Infec,doxorubicin,DB00997
,201777,DB06228,10000891,18,15894,41,16035,0.003788629,0.442901053,0.239411681,0.788827478,0.016327941,DB0622810000891_,4.114877451,-0.814408891,NA,10000891,Acute myocardial infarction,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,201779,DB01020,10002034,52,1761,55,1823,0.922195162,0.978743888,0.652899945,1.465575662,0.965694588,DB0102010002034_,0.034907657,-0.021485276,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,isosorbide mononitrate,DB01020
,201812,DB13961,10021789,82,9375,65,6349,0.353816567,0.854359773,0.608445503,1.203881884,0.523667247,DB1396110021789_,0.646898822,-0.157402894,NA,10021789,Infection,10021881,Infections and infestations,Infec,fish oil,DB13961
,201815,DB00451,10023469,77,47194,9,15410,0.001543668,2.793680153,1.397098832,6.341036888,0.007876408,DB0045110023469_,4.843883276,1.027359778,female,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,levothyroxine,DB00451
,201846,DB00051,10021425,40,25691,16,11404,0.774089809,1.109721274,0.607435701,2.123610871,0.876749952,DB0005110021425_,0.131533444,0.104108879,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,adalimumab,DB00051
,201871,DB01268,10028411,31,2112,36,3094,0.381381677,1.261426052,0.751977563,2.104941806,0.551439428,DB0126810028411_,0.595223277,0.232242868,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sunitinib,DB01268
,201877,DB00451,10040943,77,47194,32,15387,0.265296538,0.784530351,0.513001126,1.225284726,0.427286734,DB0045110040943_,0.850299984,-0.24267002,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,201906,DB00424,10010264,43,1151,7,421,0.049486775,2.245952349,0.99141986,5.964092859,0.124041375,DB0042410010264_,2.087140101,0.80912964,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,hyoscyamine,DB00424
,201907,DB00737,10010264,47,2754,13,919,0.652634056,1.20637712,0.6385621,2.441812154,0.786830849,DB0073710010264_,0.239741985,0.187621752,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,meclizine,DB00737
,201927,DB00457,10016256,44,635,13,498,0.001485803,2.652362596,1.384531407,5.428825573,0.007630778,DB0045710016256_,4.87556546,0.975450788,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,prazosin,DB00457
,201928,DB00370,10022523,35,4506,17,3646,0.093220611,1.665780499,0.906808351,3.176298984,0.200466641,DB0037010022523_,1.607107425,0.510293782,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,mirtazapine,DB00370
,201949,DB01012,10033371,55,10577,39,8646,0.533834457,1.152775641,0.750245283,1.786549269,0.690424322,DB0101210033371_,0.370448911,0.142172636,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,201955,DB01233,10043071,42,3379,26,1700,0.438308003,0.8127622,0.484938167,1.385846586,0.606731751,DB0123310043071_,0.499668511,-0.207316709,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,metoclopramide,DB01233
,201965,DB01012,10063743,130,10502,107,8578,1,0.992369608,0.761151547,1.296094445,1,DB0101210063743_,0,-0.007659652,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,cinacalcet,DB01012
,201992,DB00999,10023644,42,21388,17,12222,0.278517831,1.411783792,0.78622468,2.646483347,0.442333535,DB0099910023644_,0.815691077,0.344854006,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,hydrochlorothiazide,DB00999
,202042,DB00788,10069339,110,9246,143,4918,3.38594363053206e-12,0.409182687,0.315394775,0.529698078,1.39497693304914e-10,DB0078810069339_,22.69297305,-0.893593555,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,naproxen,DB00788
,202043,DB01190,10069339,49,4885,88,2197,3.99258784722887e-15,0.250504822,0.172272559,0.360619281,2.4839093861399e-13,DB0119010069339_,29.02377252,-1.384277108,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,clindamycin,DB01190
,202051,DB06605,10019196,88,13985,69,12964,0.336476447,1.182243951,0.852006314,1.64610604,0.505525715,DB0660510019196_,0.682156371,0.167414286,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,202052,DB00193,10039906,162,19158,105,8597,0.004188743,0.692347107,0.53751242,0.894941263,0.017735361,DB0019310039906_,4.032194829,-0.36766785,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,202053,DB00761,10039906,108,15199,67,8558,0.528406588,0.90763031,0.662230748,1.251686349,0.685783201,DB0076110039906_,0.377193734,-0.09691813,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,potassium chloride,DB00761
,202054,DB06605,10039906,49,14024,42,12991,0.753138671,1.080761983,0.700501801,1.673894248,0.861080903,DB0660510039906_,0.149566815,0.077666332,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,202064,DB00482,10009033,39,8220,11,3060,0.52376988,1.319787292,0.661857319,2.861285621,0.68185287,DB0048210009033_,0.382941378,0.277470582,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,celecoxib,DB00482
,202068,DB00230,10039906,229,19445,106,8545,0.676246614,0.949368652,0.749767538,1.208520693,0.803832237,DB0023010039906_,0.218364692,-0.051958092,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,202073,DB00722,10039906,151,25252,149,25883,0.77226019,1.038757021,0.822265749,1.312350087,0.875346993,DB0072210039906_,0.133134908,0.038024826,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,202074,DB00863,10039906,92,10581,67,5773,0.079919678,0.749219562,0.540014935,1.04405277,0.178296446,DB0086310039906_,1.724307686,-0.288723198,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,202077,DB01098,10039906,41,8108,38,7171,0.91012049,0.954242121,0.597877016,1.526439377,0.959542868,DB0109810039906_,0.041298287,-0.046837844,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,202099,DB00281,10009887,40,11418,16,5655,0.569748976,1.238129156,0.677377939,2.37049928,0.720564479,DB0028110009887_,0.327720376,0.213601495,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,202145,DB05259,10074300,56,11214,15,2713,0.763528687,0.903192579,0.502921163,1.72233877,0.86906645,DB0525910074300_,0.14033569,-0.101819483,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,glatiramer,DB05259
,202148,DB00863,10003246,56,10617,14,5826,0.007998301,2.19487766,1.204589846,4.273492936,0.029774378,DB0086310003246_,3.514107064,0.786126309,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,202152,DB00635,10007697,38,33015,16,23778,0.073468458,1.710497319,0.931038076,3.286699898,0.167305039,DB0063510007697_,1.787936552,0.536784158,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,202158,DB06655,10022086,56,3632,9,2110,7.40830732897977e-05,3.614154951,1.769531366,8.330460196,0.000616128,DB0665510022086_,7.392055291,1.284858067,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,liraglutide,DB06655
,202167,DB04951,10013968,131,1751,212,2845,1,1.003994569,0.794643788,1.264901927,1,DB0495110013968_,0,0.003986612,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pirfenidone,DB04951
,202210,DB00480,10011781,172,67256,64,67598,8.0549338651646e-13,2.701283607,2.015704307,3.658935376,3.66304388660643e-11,DB0048010011781_,24.03014156,0.99372707,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,202227,DB01015,10037884,53,9834,62,9319,0.263398356,0.810082147,0.54997399,1.189518473,0.425219616,DB0101510037884_,0.8551495,-0.210619621,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,202254,DB05679,10053762,612,6319,462,4447,0.283893453,0.932247066,0.81977231,1.060677744,0.448378514,DB0567910053762_,0.802117506,-0.070157407,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ustekinumab,DB05679
,202257,DB00254,10030095,37,5898,18,3370,0.673680893,1.174514551,0.650750707,2.195115458,0.802138219,DB0025410030095_,0.220474343,0.160854914,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,202264,DB00601,10013700,47,858,21,890,0.001221804,2.320546357,1.346937078,4.122898049,0.006489985,DB0060110013700_,5.037495131,0.841802657,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,linezolid,DB00601
,202288,DB00635,10067482,123,32930,58,23736,0.008096286,1.528583991,1.10937257,2.127527824,0.030081402,DB0063510067482_,3.503848173,0.424341811,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,202295,DB09027,10041349,32,5147,53,7099,0.441814619,0.832772334,0.518771909,1.317755144,0.609931578,DB0902710041349_,0.494408495,-0.182994982,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ledipasvir,DB09027
,202298,DB00758,10064373,103,8197,108,9966,0.297070243,1.159511546,0.875058454,1.535700828,0.462944882,DB0075810064373_,0.770147277,0.147998836,NA,10064373,Labelled drug-drug interaction medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,202299,DB00758,10076309,50,8250,60,10014,1,1.011516128,0.6799644,1.499042495,1,DB0075810076309_,0,0.011450322,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,202309,DB00112,10039906,67,5866,56,4035,0.310080539,0.822999809,0.567102016,1.198269671,0.477515128,DB0011210039906_,0.739159437,-0.194799311,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,bevacizumab,DB00112
,202335,DB00515,10069339,72,1798,106,2045,0.106490066,0.772606971,0.560723159,1.059629283,0.220844324,DB0051510069339_,1.510297241,-0.257984806,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,cisplatin,DB00515
,202352,DB06218,10041962,52,1642,62,1374,0.068940216,0.701906213,0.472507886,1.039126587,0.159417047,DB0621810041962_,1.836231573,-0.353955483,NA,10041962,Status epilepticus,10029205,Nervous system disorders,Nerv,lacosamide,DB06218
,202355,DB05676,10033433,49,47080,10,25319,0.003707942,2.635118268,1.318392192,5.836129543,0.016044657,DB0567610033433_,4.132379399,0.968928065,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,202375,DB00051,10047942,77,25654,24,11396,0.159780146,1.425229832,0.890718038,2.358484962,0.297163362,DB0005110047942_,1.213473253,0.354333087,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,adalimumab,DB00051
,202384,DB11089,10025256,33,10142,21,8386,0.41183162,1.299329657,0.729022233,2.365143175,0.581309901,DB1108910025256_,0.542471272,0.261848483,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,docusate,DB11089
,202385,DB00745,10037660,46,2531,15,1068,0.479505852,1.29391374,0.705749651,2.506373462,0.644498431,DB0074510037660_,0.439282891,0.257671532,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,modafinil,DB00745
,202404,DB00598,10011906,54,1534,43,985,0.34040253,0.806449456,0.525689954,1.243638087,0.509624679,DB0059810011906_,0.674080747,-0.215114054,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,labetalol,DB00598
,202421,DB00996,10003285,169,38784,82,22343,0.212463424,1.187335113,0.906253213,1.566037354,0.3643755,DB0099610003285_,1.009570349,0.171711395,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,202422,DB01050,10003285,73,18035,33,9338,0.540083371,1.145356148,0.748847744,1.78561768,0.695682221,DB0105010003285_,0.362862302,0.135715635,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,202427,DB01175,10037153,162,10562,48,4844,0.006973721,1.547820524,1.113108382,2.187174738,0.026709056,DB0117510037153_,3.622752614,0.436847828,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,escitalopram,DB01175
,202429,DB09270,10037153,47,3067,9,2359,1.82799094761281e-05,4.015823129,1.940555446,9.338791347,0.000184448,DB0927010037153_,8.598142185,1.39024234,female,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,ubidecarenone,DB09270
,202441,DB00582,10037844,18,1112,44,1530,0.049868995,0.56298264,0.304444653,1.000769073,0.124780981,DB0058210037844_,2.081195232,-0.574506487,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,voriconazole,DB00582
,202449,DB00316,10053459,44,65430,15,36938,0.103363269,1.655982254,0.903844862,3.20405803,0.216072434,DB0031610053459_,1.532141586,0.50439434,NA,10053459,Secretion discharge,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,202453,DB01101,10074300,47,7542,18,3890,0.357847992,1.346737153,0.766313862,2.467301662,0.527573815,DB0110110074300_,0.639466489,0.297684743,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,capecitabine,DB01101
,202455,DB00555,10069339,54,6993,37,3449,0.145241532,0.719815684,0.46410955,1.127426478,0.277396815,DB0055510069339_,1.282306254,-0.328760094,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,lamotrigine,DB00555
,202456,DB01068,10069339,104,13659,99,6741,4.18276645617886e-06,0.518444815,0.389279021,0.690873941,5.0479346327209e-05,DB0106810069339_,9.893946289,-0.656921689,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,clonazepam,DB01068
,202470,DB01222,10008531,93,9181,31,5374,0.006468871,1.755954706,1.156402215,2.732759159,0.025139982,DB0122210008531_,3.683295785,0.563012701,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,202578,DB06262,10016173,262,3538,396,3918,0.000174357,0.732707528,0.62027266,0.864496438,0.001284463,DB0626210016173_,6.657414837,-0.311008663,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,droxidopa,DB06262
,202617,DB00860,10011906,42,1841,57,1439,0.007498019,0.576050894,0.374837188,0.879032387,0.028284361,DB0086010011906_,3.565446236,-0.551559265,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,prednisolone,DB00860
,202649,DB00868,10046306,63,2921,16,1630,0.004147951,2.196908769,1.248795034,4.089181756,0.017590978,DB0086810046306_,4.040369109,0.787051267,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,benzonatate,DB00868
,202650,DB00924,10046306,89,10073,20,4231,0.010983361,1.869079888,1.139263069,3.210721589,0.038372784,DB0092410046306_,3.260406821,0.625446272,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,cyclobenzaprine,DB00924
,202651,DB11988,10046306,58,3086,15,1211,0.18822194,1.517265916,0.844721427,2.894121081,0.334307298,DB1198810046306_,1.095694656,0.416909975,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,ocrelizumab,DB11988
,202653,DB11988,10053762,121,3023,45,1181,0.860229335,1.050455866,0.734895737,1.52431238,0.934151129,DB1198810053762_,0.068117046,0.049224228,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ocrelizumab,DB11988
,202728,DB00030,10020635,32,2174,20,1801,0.400378331,1.325390027,0.732224764,2.454274114,0.570219596,DB0003010020635_,0.561733736,0.281706776,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,insulin human,DB00030
,202753,DB00421,10039906,55,8848,25,5227,0.298154683,1.299637684,0.795220829,2.179353385,0.464057073,DB0042110039906_,0.767747733,0.262085521,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,202756,DB01234,10039906,176,31449,183,32705,1,1.000138383,0.808063093,1.23763866,1,DB0123410039906_,0,0.000138373,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,202759,DB14500,10039906,53,7756,20,4053,0.265340876,1.384756486,0.812778778,2.449040622,0.427345052,DB1450010039906_,0.850163508,0.325524302,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,potassium,DB14500
,202760,DB00275,10047899,41,2019,12,1225,0.030879116,2.072603014,1.063588181,4.349630396,0.086655375,DB0027510047899_,2.445816233,0.728805312,NA,10047899,Weight increased,10022891,Investigations,Inv,olmesartan,DB00275
,202761,DB01041,10047899,35,3010,21,3097,0.059484103,1.714679813,0.968181819,3.107703128,0.142528682,DB0104110047899_,1.948212025,0.539226365,NA,10047899,Weight increased,10022891,Investigations,Inv,thalidomide,DB01041
,202762,DB01137,10047899,69,7703,35,5558,0.090819154,1.422421184,0.93243615,2.205150663,0.196548635,DB0113710047899_,1.62684537,0.352360479,NA,10047899,Weight increased,10022891,Investigations,Inv,levofloxacin,DB01137
,202766,DB00575,10051055,32,5212,20,3809,0.673304651,1.169261131,0.647416799,2.160829692,0.80182189,DB0057510051055_,0.220868779,0.156372037,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,clonidine,DB00575
,202787,DB00230,10069339,127,19547,83,8568,0.005351687,0.670704937,0.504012586,0.896550021,0.021596543,DB0023010069339_,3.835222018,-0.399425975,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,pregabalin,DB00230
,202788,DB00575,10069339,93,5151,101,3728,0.005224553,0.666460352,0.49571594,0.895147231,0.021192496,DB0057510069339_,3.85410811,-0.405774628,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,clonidine,DB00575
,202789,DB00863,10069339,197,10476,173,5667,5.9238538834307e-06,0.615989496,0.498321189,0.762035976,6.85185915625857e-05,DB0086310069339_,9.58840544,-0.484525368,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ranitidine,DB00863
,202791,DB01137,10069339,153,7619,166,5427,0.000227615,0.656551195,0.522100889,0.825174033,0.001606135,DB0113710069339_,6.433924318,-0.420754606,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,levofloxacin,DB01137
,202793,DB14500,10069339,89,7720,60,4013,0.139461646,0.771104401,0.548300615,1.090886066,0.269066074,DB1450010069339_,1.312798302,-0.259931505,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,potassium,DB14500
,202796,DB04951,10035664,94,1788,130,2927,0.231646439,1.18364515,0.891913022,1.56606673,0.387897474,DB0495110035664_,0.947014218,0.168598788,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pirfenidone,DB04951
,202808,DB00295,10005557,37,14626,32,9570,0.267853243,0.756571961,0.458204695,1.255426338,0.430244591,DB0029510005557_,0.843401416,-0.278957627,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,morphine,DB00295
,202810,DB14513,10005557,54,7123,29,3535,0.7267033,0.924115556,0.576916566,1.508041166,0.840138821,DB1451310005557_,0.174188138,-0.078918154,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,magnesium,DB14513
,202872,DB08907,10007882,27,4226,47,3863,0.007136172,0.525168496,0.31386397,0.862626361,0.027210311,DB0890710007882_,3.604159291,-0.644036123,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,canagliflozin,DB08907
,202873,DB09153,10007882,58,7741,43,5656,1,0.985532383,0.651882332,1.50020839,1,DB0915310007882_,0,-0.014573293,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,202894,DB00497,10051076,46,19221,19,16356,0.008398653,2.060098316,1.182984655,3.72471774,0.030961935,DB0049710051076_,3.474996741,0.722753708,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,202896,DB00999,10051076,33,21397,25,12214,0.338763677,0.753518609,0.434432175,1.3223724,0.50786109,DB0099910051076_,0.677547314,-0.283001564,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,202939,DB01109,10043414,19,4393,31,4239,0.08782361,0.591456931,0.315162101,1.08245918,0.191548237,DB0110910043414_,1.652615612,-0.525166411,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,heparin,DB01109
,202993,DB00788,10027417,38,9318,17,5044,0.573126937,1.209956825,0.665831112,2.288678516,0.723079655,DB0078810027417_,0.32423589,0.190584677,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,naproxen,DB00788
,203024,DB06273,10060795,54,5041,29,1381,0.004713051,0.510155931,0.317761457,0.834408158,0.019507528,DB0627310060795_,3.936954836,-0.673038853,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,tocilizumab,DB06273
,203025,DB00907,10070863,318,820,541,1270,0.279106507,0.910419572,0.769704373,1.075900755,0.442936008,DB0090710070863_,0.814329972,-0.093849717,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,cocaine,DB00907
,203027,DB00973,10001760,54,3797,9,3012,6.05764971997981e-07,4.758651702,2.325195915,10.98239704,9.18519312891084e-06,DB0097310001760_,11.59791781,1.559964372,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,ezetimibe,DB00973
,203033,DB00973,10008531,34,3817,20,3001,0.337040687,1.336516536,0.745828903,2.455743571,0.506177498,DB0097310008531_,0.680867885,0.290066629,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,203060,DB00930,10064355,54,1236,20,622,0.260775781,1.358533207,0.791699404,2.418555215,0.422281507,DB0093010064355_,0.862083109,0.306405594,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,colesevelam,DB00930
,203070,DB01109,10051792,67,4345,30,4240,0.000311294,2.179167432,1.393727199,3.480295884,0.002080436,DB0110910051792_,6.175177552,0.778942892,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,heparin,DB01109
,203099,DB00635,10013496,52,33001,19,23775,0.011020823,1.97167688,1.145893678,3.532397887,0.038460214,DB0063510013496_,3.258130977,0.678884389,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,203111,DB00448,10017944,31,5114,32,3092,0.036780818,0.585784834,0.34494757,0.99350649,0.099137949,DB0044810017944_,2.311242976,-0.534802735,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,lansoprazole,DB00448
,203129,DB00635,10022998,42,33011,26,23768,0.623185973,1.163051018,0.696485641,1.976525707,0.763301179,DB0063510022998_,0.270102595,0.15104674,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,203131,DB00448,10027175,42,5103,22,3102,0.607163626,1.160506515,0.675716795,2.045431116,0.750072656,DB0044810027175_,0.287585202,0.148856561,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,lansoprazole,DB00448
,203136,DB00635,10027951,40,33013,14,23780,0.018598201,2.058025412,1.095830028,4.096503782,0.05834621,DB0063510027951_,2.841360877,0.721746985,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,203214,DB00736,10069326,37,10554,16,5537,0.565262635,1.213174777,0.657788665,2.338067612,0.716865154,DB0073610069326_,0.332867525,0.193240706,NA,10069326,Product substitution issue,10077536,Product issues,Prod,esomeprazole,DB00736
,203218,DB00829,10012218,21,8031,48,4406,1.46673865329377e-08,0.240056498,0.13634078,0.409293478,3.17179971220293e-07,DB0082910012218_,14.96379649,-1.426880976,male,10012218,Delirium,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,203219,DB01224,10012218,50,8058,75,5842,7.80096338361294e-05,0.483348537,0.330456319,0.701757346,0.000644502,DB0122410012218_,7.347032578,-0.727017277,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,203223,DB00813,10014387,22,10550,45,10123,0.003137113,0.469120999,0.268078722,0.798364907,0.014029629,DB0081310014387_,4.266583835,-0.756894549,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,fentanyl,DB00813
,203235,DB00374,10064848,34,17682,16,5708,0.247238521,0.685992437,0.368131504,1.331984923,0.406420545,DB0037410064848_,0.90036683,-0.376888676,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,treprostinil,DB00374
,203241,DB00264,10064848,201,29406,149,24743,0.258365798,1.13506342,0.91312305,1.41353986,0.419348853,DB0026410064848_,0.869052121,0.126688526,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,203242,DB00381,10064848,175,29185,162,22725,0.122948194,0.841143537,0.674921814,1.048831226,0.245662736,DB0038110064848_,1.403795676,-0.17299296,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,203243,DB00425,10064848,61,12634,38,7446,0.834900419,0.946084193,0.620147222,1.459770036,0.914447049,DB0042510064848_,0.089435714,-0.055423715,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,zolpidem,DB00425
,203244,DB00497,10064848,68,19199,50,16325,0.460149092,1.156409242,0.790417996,1.701996201,0.627566776,DB0049710064848_,0.465905198,0.145319723,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,oxycodone,DB00497
,203245,DB00641,10064848,122,14002,92,12383,0.271273249,1.172748673,0.886348027,1.556154295,0.434027292,DB0064110064848_,0.834647863,0.159350287,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,simvastatin,DB00641
,203246,DB00695,10064848,263,27786,194,20334,0.962062828,0.992088564,0.820242266,1.20163318,0.99961741,DB0069510064848_,0.000382663,-0.007942897,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,203247,DB00722,10064848,197,25206,179,25853,0.254847675,1.128805009,0.916544833,1.390948815,0.415576099,DB0072210064848_,0.878089532,0.121159559,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,203248,DB01075,10064848,53,19895,37,11060,0.321483416,0.796336556,0.513160623,1.247379672,0.489768386,DB0107510064848_,0.713822682,-0.227733374,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,diphenhydramine,DB01075
,203249,DB01306,10064848,57,4151,31,3835,0.018088058,1.698619915,1.075668023,2.728422839,0.057069331,DB0130610064848_,2.863488413,0.529816106,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,insulin aspart,DB01306
,203250,DB06605,10064848,35,14038,34,12999,0.904168287,0.953204806,0.576997824,1.576361985,0.957497529,DB0660510064848_,0.043432138,-0.047925492,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,apixaban,DB06605
,203260,DB00215,10019974,38,11065,14,5262,0.460408029,1.290723127,0.682922683,2.581421676,0.627813949,DB0021510019974_,0.465511416,0.255202625,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,citalopram,DB00215
,203263,DB00264,10040984,77,29530,70,24822,0.678684656,0.924632507,0.659887881,1.297426614,0.805455399,DB0026410040984_,0.216347448,-0.07835891,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,203275,DB01592,10016825,56,6220,11,3056,0.003732187,2.501054272,1.294126332,5.301984655,0.016124349,DB0159210016825_,4.127424783,0.916712352,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,iron,DB01592
,203290,DB08910,10028411,67,16677,74,17414,0.800205946,0.94540098,0.66855073,1.334854265,0.891983346,DB0891010028411_,0.114307817,-0.056146124,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pomalidomide,DB08910
,203291,DB00787,10003246,53,16947,33,17215,0.030363755,1.631425347,1.036346224,2.602752998,0.085469192,DB0078710003246_,2.459599298,0.489454078,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,203294,DB00482,10006451,89,8170,12,3059,0.000278715,2.776981129,1.510420765,5.583528008,0.001901233,DB0048210006451_,6.265252465,1.021364413,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,celecoxib,DB00482
,203315,DB00997,10069339,95,5236,152,3362,3.18032467317792e-12,0.401348859,0.306111139,0.524075416,1.31541831682898e-10,DB0099710069339_,22.7516962,-0.912924258,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,doxorubicin,DB00997
,203320,DB00193,10040831,34,19286,19,8683,0.459197972,0.805693015,0.44637808,1.496075838,0.626558279,DB0019310040831_,0.467513486,-0.216052484,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,203332,DB06643,10029354,108,52313,24,7491,0.063781481,0.644389499,0.410773203,1.049802453,0.15027754,DB0664310029354_,1.895271425,-0.439451924,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,denosumab,DB06643
,203354,DB00586,10038695,35,7074,18,2787,0.360879257,0.766078596,0.421462313,1.439378349,0.53080279,DB0058610038695_,0.63336472,-0.266470509,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diclofenac,DB00586
,203357,DB00316,10019717,45,65429,34,36919,0.199231781,0.746838742,0.4677413,1.202484821,0.34812254,DB0031610019717_,1.055200736,-0.291905991,NA,10019717,Hepatitis,10019805,Hepatobiliary disorders,Hepat,acetaminophen,DB00316
,203362,DB06186,10019717,27,2182,64,3582,0.126831887,0.692597044,0.423173719,1.105788161,0.251236003,DB0618610019717_,1.38136253,-0.367306915,NA,10019717,Hepatitis,10019805,Hepatobiliary disorders,Hepat,ipilimumab,DB06186
,203388,DB01076,10043521,57,25690,28,25555,0.002186188,2.024978897,1.266340346,3.307569362,0.010463211,DB0107610043521_,4.559889916,0.705559279,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,203409,DB08910,10013971,28,16716,44,17444,0.098610237,0.664088706,0.397950264,1.091366944,0.208794109,DB0891010013971_,1.566406637,-0.409339546,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,203450,DB00531,10069339,109,7143,222,6294,3.33833350158837e-13,0.432656454,0.339946358,0.547981162,1.59687163037762e-11,DB0053110069339_,24.86038954,-0.837811275,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,cyclophosphamide,DB00531
,203451,DB00773,10069339,44,2279,115,2712,6.93384979774155e-06,0.455380892,0.312673387,0.653032786,7.88135100253563e-05,DB0077310069339_,9.448426129,-0.786621085,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,etoposide,DB00773
,203452,DB00860,10069339,26,1857,40,1456,0.00828206,0.509749499,0.297173949,0.86062411,0.030618635,DB0086010069339_,3.486146473,-0.673835852,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,prednisolone,DB00860
,203453,DB00987,10069339,87,2017,154,2774,0.070703397,0.776999528,0.586594198,1.023918976,0.162521975,DB0098710069339_,1.816942054,-0.252315536,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,cytarabine,DB00987
,203454,DB01042,10069339,17,973,41,1287,0.043156143,0.548579308,0.29034816,0.994187973,0.111980178,DB0104210069339_,2.189433401,-0.600423419,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,melphalan,DB01042
,203455,DB08889,10069339,62,3103,107,3778,0.034296011,0.705520999,0.505570964,0.977351694,0.093996211,DB0888910069339_,2.36450081,-0.348818743,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,carfilzomib,DB08889
,203456,DB08910,10069339,95,16649,120,17368,0.17144158,0.825861074,0.623694844,1.091025174,0.312799218,DB0891010069339_,1.16219377,-0.191328711,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,pomalidomide,DB08910
,203461,DB01590,10020635,30,4708,21,2846,0.66411702,0.863597161,0.477197057,1.590228658,0.795457547,DB0159010020635_,0.228837799,-0.146648868,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,everolimus,DB01590
,203484,DB06228,10051398,22,15890,41,16035,0.022553912,0.541495096,0.307029111,0.930998941,0.067849396,DB0622810051398_,2.690464788,-0.613421268,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,rivaroxaban,DB06228
,203489,DB00373,10053762,44,1788,20,1267,0.123152838,1.558735526,0.89452885,2.806014204,0.24589406,DB0037310053762_,1.402854485,0.443874932,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,timolol,DB00373
,203578,DB09153,10058080,45,7754,38,5661,0.506243677,0.864574068,0.548065552,1.370332722,0.667081842,DB0915310058080_,0.404842538,-0.1455183,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,203614,DB08911,10012735,79,1560,68,1680,0.205624534,1.251044382,0.886204123,1.770043192,0.35596805,DB0891110012735_,1.0329143,0.223978708,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,trametinib,DB08911
,203653,DB00016,10064848,31,2731,27,2263,0.894834165,0.951378335,0.547711043,1.662180968,0.955976233,DB0001610064848_,0.045022227,-0.049843467,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,erythropoietin,DB00016
,203654,DB00158,10064848,66,16749,35,8069,0.670641166,0.908468606,0.5936559,1.4117545,0.800208186,DB0015810064848_,0.222883353,-0.095994948,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,folic acid,DB00158
,203655,DB00455,10064848,46,9355,25,5093,1,1.001723028,0.601964,1.703639863,1,DB0045510064848_,0,0.001721545,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,loratadine,DB00455
,203658,DB06724,10064848,188,7741,118,3801,0.042139682,0.78234659,0.616038142,0.996735066,0.109972353,DB0672410064848_,2.20752628,-0.245457427,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,calcium carbonate,DB06724
,203659,DB11089,10064848,48,10127,31,8376,0.309035081,1.280646388,0.797823071,2.083305576,0.47637962,DB1108910064848_,0.741540221,0.247364941,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,docusate,DB11089
,203694,DB00950,10069327,46,4672,17,2039,0.679731143,1.180888908,0.662329455,2.202742791,0.80629196,DB0095010069327_,0.215309369,0.166267467,NA,10069327,Product quality issue,10077536,Product issues,Prod,fexofenadine,DB00950
,203698,DB00153,10055798,35,7388,20,3419,0.46866617,0.809898433,0.454003435,1.482908416,0.63511552,DB0015310055798_,0.453948375,-0.210846431,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,ergocalciferol,DB00153
,203702,DB00136,10033775,44,2048,17,1665,0.008990741,2.103781189,1.172896102,3.942826805,0.032704349,DB0013610033775_,3.420247222,0.743736292,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,calcitriol,DB00136
,203711,DB00115,10041569,50,18375,30,10442,0.816564918,0.947122406,0.590207559,1.543752185,0.901804956,DB0011510041569_,0.103357017,-0.054326938,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,203714,DB00381,10041569,42,29318,14,22873,0.004413468,2.340434242,1.252614068,4.640983027,0.018487999,DB0038110041569_,3.990633445,0.850336485,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,203734,DB01050,10043414,56,18052,17,9354,0.062810394,1.706881454,0.976746116,3.135429028,0.148667628,DB0105010043414_,1.906042147,0.534667994,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,203755,DB00541,10039906,62,3072,60,4237,0.052705179,1.425113279,0.979849483,2.074030906,0.130110882,DB0054110039906_,2.039368252,0.354251305,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,vincristine,DB00541
,203774,DB00193,10042458,120,19200,37,8665,0.046331212,1.463683755,1.003953958,2.17928914,0.118154255,DB0019310042458_,2.135764266,0.380956378,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,203809,DB00404,10017885,122,19770,36,9826,0.005068548,1.684303853,1.151946156,2.517596705,0.020685781,DB0040410017885_,3.878308703,0.521352335,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,203825,DB04868,10037087,73,1568,41,1475,0.009732285,1.674609205,1.118968441,2.535899366,0.034828197,DB0486810037087_,3.357327974,0.515579828,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,nilotinib,DB04868
,203838,DB00682,10076309,131,19328,72,16292,0.003678646,1.533628346,1.140852098,2.075702628,0.015949395,DB0068210076309_,4.138334397,0.427636396,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,203839,DB01234,10076309,109,31516,90,32798,0.118017885,1.260368499,0.944188289,1.68598728,0.238210798,DB0123410076309_,1.43459929,0.231404138,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,203847,DB00741,10000060,37,4057,31,3143,0.806258207,0.924664756,0.556814462,1.544955535,0.895274781,DB0074110000060_,0.11062459,-0.078324033,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,hydrocortisone,DB00741
,203848,DB00997,10000060,38,5293,20,3494,0.501180671,1.254179793,0.710347077,2.279032929,0.662635947,DB0099710000060_,0.41152954,0.226481807,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,doxorubicin,DB00997
,203874,DB01183,10013709,42,517,40,508,0.909109649,1.031700238,0.640999673,1.662655047,0.959169515,DB0118310013709_,0.041687457,0.031208158,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,naloxone,DB01183
,203875,DB00231,10030124,30,3266,21,2118,0.775608191,0.926441982,0.51151401,1.70731817,0.877779221,DB0023110030124_,0.130360173,-0.076403856,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,temazepam,DB00231
,203888,DB00787,10035484,33,16967,42,17206,0.356120435,0.796788885,0.489077262,1.288331099,0.525833533,DB0078710035484_,0.642770593,-0.227165523,NA,10035484,Plasmacytoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acyclovir,DB00787
,203895,DB08910,10035484,41,16703,52,17436,0.406176329,0.823068397,0.532573106,1.264409969,0.575754772,DB0891010035484_,0.552073452,-0.194715974,NA,10035484,Plasmacytoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pomalidomide,DB08910
,203975,DB00178,10037087,33,1404,30,1650,0.371613306,1.292620889,0.760028141,2.206300784,0.541254075,DB0017810037087_,0.61386647,0.256671854,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ramipril,DB00178
,203990,DB01118,10037087,19,3044,37,4672,0.492858552,0.788182117,0.427304299,1.40914454,0.655706183,DB0111810037087_,0.422042483,-0.238026103,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,amiodarone,DB01118
,203994,DB09027,10003988,43,5136,53,7099,0.604436955,1.121398555,0.730887942,1.711976382,0.74779372,DB0902710003988_,0.290628115,0.114576616,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ledipasvir,DB09027
,203995,DB09027,10012378,80,5099,79,7073,0.035416406,1.404631564,1.014099364,1.945975363,0.096317761,DB0902710012378_,2.340102544,0.339775036,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ledipasvir,DB09027
,203996,DB09027,10016322,47,5132,46,7106,0.113207497,1.414682888,0.920288683,2.175885541,0.230896587,DB0902710016322_,1.465785343,0.346905398,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,204009,DB00537,10059866,24,7533,39,4259,5.52573910625339e-05,0.347957761,0.199872316,0.594250818,0.000480994,DB0053710059866_,7.639656583,-1.055674184,male,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,204010,DB00601,10059866,23,882,34,877,0.17802494,0.67278496,0.375121074,1.186846821,0.321342229,DB0060110059866_,1.13524859,-0.396329524,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,linezolid,DB00601
,204027,DB01273,10047899,41,1999,12,1263,0.021818165,2.158252883,1.10760308,4.529022227,0.066203806,DB0127310047899_,2.715017325,0.769299044,NA,10047899,Weight increased,10022891,Investigations,Inv,varenicline,DB01273
,204037,DB00005,10022611,106,127976,18,42401,0.006645988,1.950990745,1.176712321,3.418806292,0.02570858,DB0000510022611_,3.660930503,0.668337318,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,etanercept,DB00005
,204051,DB00996,10052897,49,38904,26,22399,0.810790109,1.085076259,0.661094211,1.819522923,0.89822005,DB0099610052897_,0.107340197,0.081650269,NA,10052897,Nerve injury,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,204065,DB00343,10007882,76,8660,34,5061,0.233509193,1.306306303,0.859588801,2.022347517,0.39014678,DB0034310007882_,0.941232253,0.267203539,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,diltiazem,DB00343
,204087,DB00051,10054112,201,25530,105,11315,0.171757998,0.848437355,0.666061665,1.085979895,0.313115718,DB0005110054112_,1.161182452,-0.164359027,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,adalimumab,DB00051
,204088,DB00005,10075265,67,128015,21,42398,0.902197714,1.056649312,0.63891981,1.816873901,0.957195726,DB0000510075265_,0.043747388,0.055102875,NA,10075265,Body temperature abnormal,10022891,Investigations,Inv,etanercept,DB00005
,204093,DB08896,10010774,45,778,55,985,0.917650489,1.035869992,0.674644133,1.583496272,0.963391904,DB0889610010774_,0.037294988,0.035241645,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,regorafenib,DB08896
,204100,DB08910,10024264,43,16701,46,17442,0.915960839,0.976254561,0.628566,1.51361692,0.962395043,DB0891010024264_,0.038330265,-0.024031906,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,204103,DB05676,10038776,70,47059,22,25307,0.028263516,1.711079585,1.046594438,2.902839178,0.080848776,DB0567610038776_,2.515174838,0.537124508,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,204116,DB08910,10006784,44,16700,22,17466,0.004337949,2.091679565,1.226432976,3.666212944,0.018240761,DB0891010006784_,4.004096549,0.737967363,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,204156,DB08934,10069339,31,4458,64,6140,0.07540516,0.667154322,0.41909561,1.041866274,0.170482077,DB0893410069339_,1.76912511,-0.404733893,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,sofosbuvir,DB08934
,204157,DB09027,10001760,97,5082,23,7129,4.45393738554694e-18,5.916051932,3.718008611,9.781509219,3.87014030344136e-16,DB0902710001760_,35.48807073,1.777669323,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,ledipasvir,DB09027
,204158,DB06643,10038153,57,52364,16,7499,0.021069286,0.510169398,0.288739055,0.952348653,0.064426035,DB0664310038153_,2.742237462,-0.673012456,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,denosumab,DB06643
,204183,DB00836,10007559,42,5493,31,4044,1,0.997445591,0.611089185,1.644271911,1,DB0083610007559_,0,-0.002557677,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,loperamide,DB00836
,204192,DB00874,10038695,43,3292,42,1934,0.023226714,0.601560331,0.382358576,0.9468364,0.069416053,DB0087410038695_,2.667637123,-0.508228447,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,guaifenesin,DB00874
,204194,DB00422,10011224,37,3398,29,2920,0.804227468,1.09633541,0.654320382,1.85328123,0.894171946,DB0042210011224_,0.111857188,0.091973173,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylphenidate,DB00422
,204204,DB00722,10062352,42,25361,22,26010,0.011791148,1.957907966,1.142178884,3.44526334,0.040604,DB0072210062352_,3.203888692,0.671876539,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,lisinopril,DB00722
,204206,DB08910,10062352,45,16699,27,17461,0.024483124,1.742678165,1.057642568,2.922308633,0.072363682,DB0891010062352_,2.62605074,0.555423105,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,204207,DB05676,10000060,196,46933,116,25213,0.405560292,0.907707685,0.717436677,1.152699343,0.575167383,DB0567610000060_,0.55309418,-0.096832885,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,204212,DB00722,10066901,43,25360,59,25973,0.165047781,0.746436906,0.491608491,1.125161127,0.304205941,DB0072210066901_,1.190050369,-0.292444186,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,204227,DB09145,10019860,105,894,24,444,0.000507703,2.17181251,1.360386205,3.592383875,0.003127484,DB0914510019860_,5.767526358,0.775562077,NA,10019860,Hereditary angioedema,10010331,"Congenital, familial and genetic disorders",Cong,water,DB09145
,204229,DB00203,10075192,47,13831,23,8915,0.326869668,1.317139685,0.783287599,2.274515689,0.495294624,DB0020310075192_,0.702602493,0.27546248,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,sildenafil,DB00203
,204230,DB08932,10075192,94,19349,31,6566,1,1.028996121,0.678427732,1.599822447,1,DB0893210075192_,0,0.028583687,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,macitentan,DB08932
,204236,DB01098,10037153,134,8015,72,7137,0.000546099,1.657177308,1.233038762,2.242747895,0.00331928,DB0109810037153_,5.708007527,0.505115738,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,rosuvastatin,DB01098
,204341,DB00668,10043071,67,10024,43,4260,0.036816365,0.662198668,0.444087886,0.996825206,0.099219084,DB0066810043071_,2.310424904,-0.412189665,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,epinephrine,DB00668
,204342,DB00213,10003246,71,18824,42,13379,0.389680248,1.20147194,0.808573514,1.805220193,0.559590545,DB0021310003246_,0.580549933,0.183547421,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,204357,DB00381,10066152,83,29277,28,22859,7.17704844416579e-05,2.314393694,1.491340501,3.691726008,0.000599456,DB0038110066152_,7.41948843,0.83914775,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,amlodipine,DB00381
,204415,DB00005,10018304,71,128011,20,42399,0.627503194,1.175804354,0.70755558,2.039681026,0.766909446,DB0000510018304_,0.265386548,0.16195247,NA,10018304,Glaucoma,10015919,Eye disorders,Eye,etanercept,DB00005
,204428,DB01005,10028813,74,1021,28,839,0.000454834,2.170887206,1.373184311,3.518528612,0.002853978,DB0100510028813_,5.859041477,0.775135934,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,hydroxyurea,DB01005
,204429,DB01005,10047700,35,1060,23,844,0.505169503,1.211531076,0.689911038,2.165447406,0.666083792,DB0100510047700_,0.406339803,0.191884911,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,hydroxyurea,DB01005
,204431,DB01005,10061428,32,1063,20,847,0.479624165,1.274726023,0.701249546,2.369948444,0.644575927,DB0100510061428_,0.439162655,0.242731272,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,hydroxyurea,DB01005
,204439,DB00316,10064848,320,65154,230,36723,0.005730186,0.784204027,0.659561335,0.933503288,0.022820423,DB0031610064848_,3.780099412,-0.243086055,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,204440,DB00476,10064848,72,17185,21,6156,0.479391898,1.228161572,0.745858193,2.104947836,0.644411171,DB0047610064848_,0.439418293,0.205518394,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,duloxetine,DB00476
,204441,DB00996,10064848,193,38760,106,22319,0.71829745,1.048439768,0.822524495,1.342396912,0.833618427,DB0099610064848_,0.181979503,0.047303124,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,204442,DB01104,10064848,56,15407,23,7263,0.630398985,1.147763966,0.694258173,1.956033932,0.769328241,DB0110410064848_,0.26223756,0.137815672,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,sertraline,DB01104
,204443,DB01592,10064848,35,6241,20,3047,0.567281294,0.8544151,0.478831315,1.56485434,0.718475502,DB0159210064848_,0.33062367,-0.157338138,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,iron,DB01592
,204451,DB00158,10076309,113,16702,56,8048,0.869302693,0.972297407,0.698951521,1.366093296,0.941838249,DB0015810076309_,0.059921729,-0.028093547,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,204452,DB00993,10076309,49,3200,26,1593,0.805469831,0.938198482,0.569347438,1.578989422,0.894731171,DB0099310076309_,0.111231973,-0.063793751,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,azathioprine,DB00993
,204453,DB01006,10076309,43,5904,41,136,3.73523917350588e-42,0.024218594,0.014890436,0.039446874,1.57089218680963e-39,DB0100610076309_,89.3491749,-3.720634575,male,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,letrozole,DB01006
,204454,DB11089,10076309,82,10093,52,8355,0.139310222,1.305359115,0.90994934,1.887319622,0.268891848,DB1108910076309_,1.313446033,0.266478187,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,204461,DB06285,10022095,64,8786,6,1100,0.701122754,1.335419847,0.579082412,3.782613286,0.820482419,DB0628510022095_,0.197862796,0.289245735,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,204466,DB00863,10061623,46,10627,32,5808,0.288433,0.785669402,0.489009898,1.276263044,0.453455411,DB0086310061623_,0.790858336,-0.241219183,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,204477,DB00316,10017964,47,65427,26,36927,1,1.020261966,0.618920323,1.71656139,1,DB0031610017964_,0,0.020059424,NA,10017964,Gastrointestinal infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,204509,DB00472,10061284,40,10719,21,4291,0.321616158,0.762511622,0.438427711,1.362951068,0.489906036,DB0047210061284_,0.71354167,-0.271137529,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,204565,DB00795,10037162,44,4525,36,1467,7.02759537873069e-05,0.396314694,0.248248892,0.636376167,0.000588656,DB0079510037162_,7.437668089,-0.925546701,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfasalazine,DB00795
,204566,DB01097,10037162,78,6187,23,1480,0.375486922,0.811261526,0.502052191,1.358676375,0.545332971,DB0109710037162_,0.606358714,-0.209164803,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,204587,DB00230,10011781,54,19620,10,8641,0.009264885,2.378197011,1.198306525,5.240778811,0.033486077,DB0023010011781_,3.396625552,0.866342642,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,pregabalin,DB00230
,204590,DB00999,10011781,85,21345,16,12223,6.45492838840661e-06,3.042058602,1.768592178,5.564679194,7.39776728533977e-05,DB0099910011781_,9.511747228,1.112534458,female,10011781,Cystitis,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,204616,DB00230,10049816,34,19640,16,8635,0.877971329,0.934289767,0.501517323,1.813698232,0.948285522,DB0023010049816_,0.053099639,-0.067968645,NA,10049816,Muscle tightness,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,204661,DB01068,10012374,64,13699,27,6813,0.505294046,1.178844393,0.740242458,1.924970337,0.666231296,DB0106810012374_,0.406118378,0.164534631,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,204681,DB00996,10015946,47,38906,16,22409,0.067914273,1.69192092,0.941863868,3.197544629,0.157563078,DB0099610015946_,1.847929403,0.525864522,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,gabapentin,DB00996
,204684,DB00557,10016322,99,5888,28,3039,0.004440195,1.824795099,1.186138739,2.891004857,0.018574128,DB0055710016322_,3.985985628,0.601467706,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,204717,DB00175,10035598,45,8086,27,6079,0.403943034,1.252968486,0.759825989,2.102659401,0.573647557,DB0017510035598_,0.555740083,0.225515525,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,204728,DB00996,10011985,31,38922,28,22397,0.103588615,0.637120753,0.369664787,1.102618065,0.216404024,DB0099610011985_,1.530608137,-0.450796076,NA,10011985,Decubitus ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,204804,DB01373,10049088,75,22645,7,7374,0.000418151,3.488946102,1.611545802,8.978344706,0.002658058,DB0137310049088_,5.930159359,1.249599714,female,10049088,Osteopenia,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,204870,DB00091,10005750,55,5455,15,2655,0.05392915,1.784488449,0.991768125,3.407569942,0.132367887,DB0009110005750_,2.022170208,0.579131791,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,cyclosporine,DB00091
,204875,DB00091,10033425,96,5414,21,2649,0.000462108,2.236553544,1.380230209,3.786018249,0.002892169,DB0009110033425_,5.845748514,0.804936085,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclosporine,DB00091
,204907,DB00213,10028391,88,18807,46,13375,0.095387747,1.360488151,0.941240979,1.989502961,0.203854955,DB0021310028391_,1.590346544,0.30784357,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,204908,DB00213,10044034,41,18854,29,13392,1,1.00421745,0.608777994,1.676500057,1,DB0021310044034_,0,0.004208582,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,204910,DB00213,10044565,202,18693,119,13302,0.110950063,1.2079164,0.957272837,1.52970959,0.227526615,DB0021310044565_,1.480488057,0.188896892,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,204911,DB00213,10048334,67,18828,24,13397,0.003777065,1.986350768,1.228886872,3.313379895,0.016284779,DB0021310048334_,4.11752441,0.68629917,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,204927,DB08932,10033433,820,18623,243,6354,0.061115673,1.151334314,0.993625512,1.337872499,0.145496374,DB0893210033433_,1.927604117,0.140921543,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,204932,DB06674,10010264,75,4431,30,1460,0.363779981,0.823748494,0.530340069,1.309085511,0.533338361,DB0667410010264_,0.628599233,-0.193890021,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,golimumab,DB06674
,204935,DB06674,10013573,62,4444,10,1480,0.028282246,2.064712094,1.047425184,4.528744664,0.080887745,DB0667410013573_,2.514692946,0.724990795,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,golimumab,DB06674
,204945,DB00051,10040984,37,25694,17,11403,0.883565664,0.965917626,0.530200858,1.830167913,0.951303696,DB0005110040984_,0.049921923,-0.034676721,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,adalimumab,DB00051
,204959,DB00572,10001760,39,2863,13,2113,0.010950687,2.213770981,1.153279629,4.531576398,0.038276438,DB0057210001760_,3.26292077,0.794697388,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,atropine,DB00572
,204978,DB11089,10006002,57,10118,30,8377,0.051450174,1.573026921,0.992964906,2.538281298,0.127738531,DB1108910006002_,2.05776983,0.453001738,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,204992,DB00572,10010774,74,2828,45,2081,0.348210653,1.210028196,0.820415415,1.801964865,0.517775472,DB0057210010774_,0.658213582,0.190643662,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,atropine,DB00572
,204995,DB11074,10011906,41,1219,37,831,0.241203373,0.755516802,0.468059964,1.223106032,0.399358334,DB1107410011906_,0.917896185,-0.280353258,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dimethicone,DB11074
,204996,DB01142,10013573,51,1689,15,769,0.176947682,1.547771089,0.850211011,2.983182235,0.319975704,DB0114210013573_,1.139510211,0.436815889,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,doxepin,DB01142
,205003,DB00433,10013911,68,7588,53,5967,1,1.008931354,0.692956833,1.475749,1,DB0043310013911_,0,0.008891705,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,205008,DB06228,10013911,40,15872,32,16044,0.346615335,1.26353361,0.773505966,2.079061883,0.516060159,DB0622810013911_,0.661531933,0.233912248,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,205015,DB01268,10015150,50,2093,52,3078,0.084349459,1.413930512,0.935567216,2.135075331,0.185642263,DB0126810015150_,1.683933777,0.346373423,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,sunitinib,DB01268
,205022,DB00213,10017533,41,18854,15,13406,0.029166153,1.943469779,1.052715411,3.781892658,0.082864497,DB0021310017533_,2.490548577,0.664474922,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,205024,DB00264,10017533,62,29545,34,24858,0.050913042,1.534230309,0.993754379,2.405304795,0.126730865,DB0026410017533_,2.065689614,0.428028828,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,205049,DB00268,10020642,35,2940,16,1529,0.767201499,1.137607383,0.610986274,2.208644851,0.872045507,DB0026810020642_,0.136913669,0.12892727,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,ropinirole,DB00268
,205050,DB00433,10020642,45,7611,41,5979,0.514420258,0.862226164,0.551267538,1.351912041,0.67437403,DB0043310020642_,0.393970382,-0.148237671,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,prochlorperazine,DB00433
,205055,DB01409,10020642,32,5999,20,3946,0.888143389,1.052442686,0.582810387,1.944537278,0.953646495,DB0140910020642_,0.047462226,0.05111383,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,tiotropium,DB01409
,205068,DB00572,10028334,49,2853,31,2095,0.569249593,1.160635621,0.722618909,1.890017977,0.720198377,DB0057210028334_,0.328228582,0.148967804,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,atropine,DB00572
,205126,DB00904,10031009,94,22975,42,14414,0.077130276,1.404118266,0.965449127,2.072657545,0.173427657,DB0090410031009_,1.751994731,0.339409537,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,205142,DB00956,10043607,33,5781,24,3443,0.493043943,0.818938374,0.468669225,1.450677372,0.655851033,DB0095610043607_,0.4218216,-0.199746443,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,hydrocodone,DB00956
,205169,DB00904,10047461,98,22971,57,14399,0.680000011,1.077722691,0.769192025,1.52230237,0.806455783,DB0090410047461_,0.215106209,0.074850196,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,ondansetron,DB00904
,205174,DB00646,10047895,71,3382,48,1952,0.441755482,0.853766902,0.581009964,1.263950516,0.609894929,DB0064610047895_,0.494468584,-0.158097071,NA,10047895,Weight decreased,10022891,Investigations,Inv,nystatin,DB00646
,205203,DB09140,10050584,54,3687,13,1785,0.024835335,2.010795767,1.079455635,4.027411194,0.073134301,DB0914010050584_,2.615457792,0.698530548,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,oxygen,DB09140
,205211,DB00695,10052428,65,27984,30,20498,0.037452275,1.587043815,1.014396264,2.535318629,0.10048868,DB0069510052428_,2.297710196,0.46187305,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,205233,DB01076,10060820,38,25709,22,25561,0.051829001,1.717301202,0.989822208,3.049404293,0.128484889,DB0107610060820_,2.051943976,0.54075399,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,205245,DB09020,10061818,34,1920,21,1583,0.340195366,1.334762767,0.749242298,2.430602121,0.509358046,DB0902010061818_,0.674604079,0.288753574,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,bisacodyl,DB09020
,205291,DB06282,10003239,73,1467,9,524,0.001144917,2.895868031,1.431381979,6.632019521,0.006161779,DB0628210003239_,5.089389665,1.063284904,female,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,levocetirizine,DB06282
,205295,DB00455,10013786,55,9346,18,5100,0.065057317,1.667325616,0.962901395,3.020685354,0.152531583,DB0045510013786_,1.880383602,0.511220915,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,loratadine,DB00455
,205341,DB00402,10013968,47,1305,29,667,0.459638052,0.828443372,0.505409949,1.37845831,0.627109921,DB0040210013968_,0.466633441,-0.188206794,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,eszopiclone,DB00402
,205366,DB00413,10016322,37,2162,16,1191,0.471487735,1.273847182,0.687945261,2.46351209,0.637699656,DB0041310016322_,0.449887865,0.242041599,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,pramipexole,DB00413
,205367,DB00687,10016322,33,953,23,1062,0.103131641,1.598510048,0.903436701,2.873014032,0.215700432,DB0068710016322_,1.533864721,0.469071975,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,fludrocortisone,DB00687
,205370,DB09035,10000081,91,4635,98,6592,0.062567897,1.320585393,0.979194696,1.779567876,0.148235357,DB0903510000081_,1.90895402,0.278075118,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,nivolumab,DB09035
,205371,DB09035,10009887,153,4573,207,6483,0.664049505,1.047807018,0.841636316,1.302261041,0.795412926,DB0903510009887_,0.228893896,0.046699426,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,nivolumab,DB09035
,205372,DB09035,10012735,191,4535,259,6431,0.660456555,1.045795909,0.85945447,1.270660853,0.79272646,DB0903510012735_,0.232277061,0.044778231,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,nivolumab,DB09035
,205390,DB00203,10039906,90,13788,76,8862,0.093472221,0.761152882,0.553945042,1.048227854,0.20085982,DB0020310039906_,1.605148028,-0.272921045,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,205391,DB00374,10039906,82,17634,32,5692,0.381816435,0.827124888,0.54291144,1.288009632,0.551932209,DB0037410039906_,0.59433005,-0.189799583,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,205393,DB08932,10039906,101,19342,41,6556,0.333799658,0.834956183,0.574749228,1.23288372,0.502877265,DB0893210039906_,0.687409144,-0.18037603,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,205405,DB00169,10045285,46,38645,13,18162,0.123788023,1.662957996,0.883129049,3.356066524,0.24677802,DB0016910045285_,1.399266052,0.508597942,NA,10045285,Ulcer,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,205419,DB00695,10062070,36,28013,43,20485,0.030463353,0.612243408,0.381842211,0.976388467,0.085685312,DB0069510062070_,2.457073851,-0.49062535,NA,10062070,Peritonitis bacterial,10021881,Infections and infestations,Infec,furosemide,DB00695
,205420,DB01076,10062070,21,25726,33,25550,0.10359671,0.632019414,0.347398797,1.125766527,0.216406225,DB0107610062070_,1.530597965,-0.458835167,NA,10062070,Peritonitis bacterial,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,205438,DB00047,10022000,64,9221,57,8461,0.927319467,1.030268301,0.708685345,1.500976107,0.969361391,DB0004710022000_,0.031117784,0.029819254,NA,10022000,Influenza,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,205443,DB00706,10022000,16,1059,124,15801,0.021270925,1.925193785,1.063179653,3.266590612,0.064921767,DB0070610022000_,2.734572326,0.65502663,NA,10022000,Influenza,10021881,Infections and infestations,Infec,tamsulosin,DB00706
,205447,DB01306,10022000,28,4180,33,3833,0.368586408,0.778075602,0.452049426,1.330621207,0.538285042,DB0130610022000_,0.619367041,-0.250931585,NA,10022000,Influenza,10021881,Infections and infestations,Infec,insulin aspart,DB01306
,205459,DB00540,10037660,44,2439,15,1076,0.476307422,1.293953906,0.70271353,2.51451296,0.641676008,DB0054010037660_,0.443671763,0.257702574,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,nortriptyline,DB00540
,205460,DB00658,10037660,18,1285,33,1363,0.066457239,0.578680631,0.305145722,1.064148386,0.154979522,DB0065810037660_,1.864462287,-0.547004542,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,sevelamer,DB00658
,205468,DB00540,10046571,63,2420,16,1075,0.047906306,1.748853078,0.992511812,3.259720452,0.121195115,DB0054010046571_,2.110353509,0.558960189,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,nortriptyline,DB00540
,205469,DB00737,10046571,90,2711,10,922,0.000234515,3.060380496,1.580688026,6.625943299,0.001644674,DB0073710046571_,6.410213046,1.118539253,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,meclizine,DB00737
,205513,DB01060,10010264,110,8477,69,5012,0.6978173,0.942572118,0.68980654,1.295505738,0.818262715,DB0106010010264_,0.200571827,-0.059142844,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,205514,DB01060,10048762,33,8554,22,5059,0.676455788,0.887139736,0.501314588,1.599046772,0.80384645,DB0106010048762_,0.21834701,-0.119752772,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,205524,DB00390,10016322,79,4066,31,3270,0.000647409,2.04927365,1.333143327,3.221293055,0.00383788,DB0039010016322_,5.562835249,0.717485413,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,205528,DB00188,10017413,118,7768,96,8732,0.019203254,1.381668803,1.044497624,1.831420076,0.059872788,DB0018810017413_,2.815533174,0.323292046,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,bortezomib,DB00188
,205529,DB00695,10017413,189,27860,133,20395,0.777238354,1.040290187,0.828279887,1.309604449,0.878546063,DB0069510017413_,0.129486939,0.0394997,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,furosemide,DB00695
,205544,DB08895,10067152,79,28035,9,6637,0.030130398,2.077984329,1.040236794,4.714110652,0.084980688,DB0889510067152_,2.46533125,0.731398351,NA,10067152,Oral herpes,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,205548,DB08910,10021425,44,16700,49,17439,0.835588135,0.937673848,0.609309741,1.439184435,0.914871949,DB0891010021425_,0.08897117,-0.064353101,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,pomalidomide,DB08910
,205568,DB08896,10005750,58,765,72,968,0.92726089,1.019311974,0.699043273,1.48104792,0.969361391,DB0889610005750_,0.031117784,0.019127865,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,regorafenib,DB08896
,205577,DB00678,10029216,56,15543,21,10703,0.019569409,1.836236661,1.093675808,3.195005271,0.060762143,DB0067810029216_,2.800788326,0.607718184,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,losartan,DB00678
,205618,DB00158,10006784,61,16754,16,8088,0.028077927,1.840445622,1.047072197,3.422197134,0.080403998,DB0015810006784_,2.520691375,0.610007728,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,205620,DB00321,10006784,46,7401,22,2828,0.414547638,0.798954945,0.469974038,1.397270736,0.583771378,DB0032110006784_,0.538245848,-0.224450724,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,205650,DB00853,10054112,37,1784,46,2220,1,1.000925891,0.628256726,1.585043851,1,DB0085310054112_,0,0.000925463,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,temozolomide,DB00853
,205651,DB01234,10054112,84,31541,59,32829,0.023458575,1.481849851,1.049268831,2.104566016,0.069945963,DB0123410054112_,2.660032291,0.393291207,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,dexamethasone,DB01234
,205655,DB00451,10012318,46,47225,9,15410,0.208809328,1.667737061,0.806348917,3.876442203,0.359869729,DB0045110012318_,1.022013176,0.511467654,NA,10012318,Dental caries,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,205659,DB08932,10033557,620,18823,102,6495,1.115540575539e-13,2.097402455,1.695107695,2.616983596,5.66061467722829e-12,DB0893210033557_,25.89748863,0.740699653,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,macitentan,DB08932
,205662,DB08932,10042604,41,19402,13,6584,1,1.070243475,0.561788281,2.17831655,1,DB0893210042604_,0,0.06788617,NA,10042604,Supraventricular tachycardia,10007541,Cardiac disorders,Card,macitentan,DB08932
,205674,DB01590,10005750,64,4674,113,2754,1.49665886410338e-12,0.333765812,0.240810396,0.459292439,6.52940717725433e-11,DB0159010005750_,23.45211987,-1.097315694,male,10005750,Blood pressure increased,10022891,Investigations,Inv,everolimus,DB01590
,205692,DB00030,10005554,32,2174,26,1795,1,1.016202686,0.584279043,1.782495901,1,DB0003010005554_,0,0.016072823,NA,10005554,Blood glucose abnormal,10022891,Investigations,Inv,insulin human,DB00030
,205715,DB00678,10018484,38,15561,26,10698,1,1.004789963,0.593935219,1.724705833,1,DB0067810018484_,0,0.004778528,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,losartan,DB00678
,205719,DB06637,10018484,35,6127,15,2004,0.410366335,0.763206373,0.405166152,1.507448644,0.579751524,DB0663710018484_,0.545155674,-0.270226808,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,dalfampridine,DB06637
,205731,DB01156,10000060,77,13545,27,6301,0.244997597,1.3266862,0.84490834,2.142057224,0.403748128,DB0115610000060_,0.906964041,0.282684254,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,bupropion,DB01156
,205787,DB00727,10035226,15,3828,39,4134,0.003699351,0.415426488,0.212373224,0.772206335,0.016020803,DB0072710035226_,4.13386723,-0.878449606,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,nitroglycerin,DB00727
,205789,DB00706,10069339,14,1061,298,15627,0.197266449,0.691937354,0.372349014,1.184917314,0.345688097,DB0070610069339_,1.062218364,-0.368259856,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,tamsulosin,DB00706
,205790,DB00727,10069339,60,3783,114,4059,0.000388539,0.564756475,0.404745084,0.781316221,0.002504355,DB0072710069339_,5.989724059,-0.571360658,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,nitroglycerin,DB00727
,205852,DB00761,10064848,96,15211,61,8564,0.454359514,0.886062348,0.635457262,1.243643281,0.621844775,DB0076110064848_,0.475064775,-0.12096796,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,potassium chloride,DB00761
,205855,DB00175,10069339,127,8004,139,5967,0.002135048,0.681172389,0.52991705,0.874898916,0.010267055,DB0017510069339_,4.578815016,-0.383939864,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,pravastatin,DB00175
,205856,DB01109,10069339,115,4297,199,4071,2.73402618893413e-07,0.547537602,0.429594347,0.695251214,4.49430133684388e-06,DB0110910069339_,12.31270033,-0.60232414,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,heparin,DB01109
,205857,DB01225,10069339,142,4902,170,4470,0.021085552,0.761707047,0.602896131,0.961171131,0.064468272,DB0122510069339_,2.741582079,-0.272193251,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,enoxaparin,DB01225
,205872,DB00512,10051792,28,4709,37,5061,0.455814605,0.813342747,0.478599887,1.367937146,0.623219688,DB0051210051792_,0.472856193,-0.206602675,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,vancomycin,DB00512
,205876,DB00423,10053762,56,2411,28,1012,0.468863597,0.839547267,0.520874082,1.381221527,0.635278211,DB0042310053762_,0.453692249,-0.1748925,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,methocarbamol,DB00423
,205897,DB00374,10013952,92,17624,10,5714,0.000287312,2.982808459,1.549435461,6.431155139,0.0019479,DB0037410013952_,6.241003331,1.092865293,female,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,205898,DB00421,10013952,38,8865,12,5240,0.057253918,1.871703289,0.956434231,3.938241061,0.138288006,DB0042110013952_,1.978416766,0.626848866,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,spironolactone,DB00421
,205902,DB01136,10013952,41,9843,29,11086,0.055676837,1.592279908,0.965016025,2.658671836,0.135493535,DB0113610013952_,1.998831354,0.465166894,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carvedilol,DB01136
,205928,DB00921,10001497,27,5818,40,4863,0.026087513,0.564239134,0.332432833,0.943995096,0.075924297,DB0092110001497_,2.578018525,-0.572277122,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,205931,DB00921,10042128,92,5753,38,4865,0.000175627,2.047181136,1.38566636,3.077798238,0.001292914,DB0092110042128_,6.650856798,0.716463791,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,buprenorphine,DB00921
,205932,DB08932,10029223,63,19380,11,6586,0.043646607,1.946392837,1.016384944,4.09826817,0.112893144,DB0893210029223_,2.181313539,0.665977832,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,205940,DB00028,10000060,113,13345,25,5590,0.002644753,1.893298529,1.217641703,3.052008066,0.012197092,DB0002810000060_,4.406557755,0.638320561,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,human immunoglobulin g,DB00028
,205974,DB09037,10010305,30,2496,37,2798,0.713823843,0.90895236,0.540580483,1.517026713,0.830288509,DB0903710010305_,0.185982038,-0.095462595,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,pembrolizumab,DB09037
,205983,DB01409,10016825,40,5991,11,3955,0.009130079,2.400374021,1.20695856,5.194205371,0.033101257,DB0140910016825_,3.408184015,0.875624567,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,tiotropium,DB01409
,205984,DB01109,10020751,36,4376,23,4247,0.119125595,1.518997077,0.8741843,2.689701355,0.240004313,DB0110910020751_,1.427098384,0.418050299,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,heparin,DB01109
,205985,DB09140,10020751,45,3696,13,1785,0.120508281,1.671625522,0.88341415,3.386663957,0.242103426,DB0914010020751_,1.418390266,0.513796519,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,oxygen,DB09140
,205995,DB00480,10021425,141,67287,114,67548,0.090570423,1.241635222,0.962897473,1.603947399,0.196152842,DB0048010021425_,1.628861117,0.216429238,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,lenalidomide,DB00480
,205996,DB00181,10003285,41,9815,19,5852,0.423124766,1.286584842,0.729225396,2.349360156,0.5919963,DB0018110003285_,0.524254895,0.251991299,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,baclofen,DB00181
,205999,DB00497,10003285,85,19182,69,16306,0.80824582,1.047193776,0.752708621,1.461216427,0.896499722,DB0049710003285_,0.109257296,0.046113992,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,206000,DB00697,10003285,48,6048,11,1795,0.534284182,1.295046137,0.661477631,2.771394302,0.690882134,DB0069710003285_,0.369786043,0.258546322,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,tizanidine,DB00697
,206001,DB00423,10003988,67,2400,27,1013,0.909133134,1.047373043,0.656335856,1.7142563,0.959169515,DB0042310003988_,0.041687457,0.046285166,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,methocarbamol,DB00423
,206013,DB01069,10028391,40,6660,10,2385,0.339281244,1.432341493,0.702540157,3.217298657,0.508363324,DB0106910028391_,0.676558882,0.359310513,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,promethazine,DB01069
,206015,DB01069,10033775,76,6624,18,2377,0.125961065,1.515008289,0.895092219,2.697856424,0.250029194,DB0106910033775_,1.386177593,0.41542091,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,206065,DB00697,10061428,74,6022,17,1789,0.381202644,1.293112632,0.753332513,2.34365838,0.551230623,DB0069710061428_,0.595602004,0.257052205,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,tizanidine,DB00697
,206074,DB00374,10075192,48,17668,26,5698,0.041007001,0.595407477,0.361705503,1.000775609,0.107673844,DB0037410075192_,2.228648589,-0.518509273,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,treprostinil,DB00374
,206075,DB00682,10075192,58,19401,55,16309,0.570640979,0.886483055,0.601953504,1.306925963,0.721137438,DB0068210075192_,0.326925539,-0.120493268,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,warfarin,DB00682
,206086,DB00072,10013709,62,3661,13,322,0.008995038,0.419599967,0.225304024,0.841028195,0.03271319,DB0007210013709_,3.419976934,-0.86845348,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,trastuzumab,DB00072
,206092,DB05259,10047899,72,11198,7,2721,0.014802955,2.499236333,1.151004535,6.445346399,0.048807786,DB0525910047899_,3.019865425,0.915985218,NA,10047899,Weight increased,10022891,Investigations,Inv,glatiramer,DB05259
,206156,DB01229,10051055,57,5684,33,2676,0.364143771,0.813231994,0.519272122,1.29244828,0.533707986,DB0122910051055_,0.627906433,-0.206738855,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,paclitaxel,DB01229
,206169,DB00993,10013700,142,3107,45,1574,0.006955483,1.598455948,1.128882336,2.300849611,0.026664459,DB0099310013700_,3.624423741,0.469038131,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,azathioprine,DB00993
,206187,DB00343,10003553,69,8667,16,5079,0.000411104,2.527044449,1.449519353,4.669701862,0.002621023,DB0034310003553_,5.944190639,0.927050418,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,206192,DB00924,10033661,22,10140,30,4221,2.39536510562327e-05,0.305310853,0.167563982,0.548001894,0.000232719,DB0092410033661_,8.365678105,-1.186424832,male,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,cyclobenzaprine,DB00924
,206193,DB08868,10073085,119,9083,27,2484,0.41817786,1.205307753,0.786242371,1.909296115,0.587189498,DB0886810073085_,0.532407686,0.186734931,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,fingolimod,DB08868
,206197,DB00374,10013786,49,17667,11,5713,0.365803041,1.440425379,0.738321376,3.074278554,0.535393559,DB0037410013786_,0.624753179,0.364938472,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,treprostinil,DB00374
,206205,DB01240,10037884,69,5682,13,1563,0.278495553,1.459951582,0.797495313,2.886965542,0.442311517,DB0124010037884_,0.815740855,0.378403272,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,epoprostenol,DB01240
,206206,DB08932,10040829,47,19396,21,6576,0.327705112,0.758810215,0.444351929,1.337443562,0.496182539,DB0893210040829_,0.700811398,-0.276003579,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,macitentan,DB08932
,206224,DB06403,10057925,41,21430,16,6645,0.436489379,0.794585258,0.435985955,1.517892483,0.605090624,DB0640310057925_,0.502377041,-0.229934988,NA,10057925,Transplant evaluation,10022891,Investigations,Inv,ambrisentan,DB06403
,206247,DB01104,10046543,42,15421,18,7268,0.783536762,1.099705302,0.61895924,2.031129339,0.882171087,DB0110410046543_,0.125369266,0.095042237,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,sertraline,DB01104
,206283,DB00126,10053425,53,10118,7,5938,2.01866708815866e-05,4.443160204,2.011288275,11.59200362,0.000201369,DB0012610053425_,8.510372776,1.491365881,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,206291,DB00697,10022095,44,6052,10,1796,0.518084627,1.3057004,0.645774862,2.915561122,0.677438866,DB0069710022095_,0.389435965,0.266739602,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,206349,DB00374,10072878,53,17663,10,5714,0.14101021,1.714456736,0.8625094,3.78220959,0.271306472,DB0037410072878_,1.304506206,0.539096258,NA,10072878,Device use error,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,206357,DB00338,10040882,58,33616,49,22223,0.235381112,0.782520705,0.525506734,1.16942195,0.392500784,DB0033810040882_,0.935216743,-0.245234897,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,206366,DB00091,10042128,43,5467,22,2648,0.894428542,0.946712106,0.552599832,1.66549511,0.955931269,DB0009110042128_,0.045069263,-0.054760238,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,cyclosporine,DB00091
,206370,DB00091,10076309,44,5466,25,2645,0.521137284,0.851692708,0.508662231,1.455490884,0.680064167,DB0009110076309_,0.385568122,-0.160529489,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclosporine,DB00091
,206371,DB00153,10076309,49,7374,20,3419,0.698057462,1.1359383,0.661669123,2.020798457,0.818414344,DB0015310076309_,0.200386537,0.127459005,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ergocalciferol,DB00153
,206372,DB00215,10076309,86,11017,31,5245,0.197753053,1.320770013,0.865468866,2.063700341,0.346263798,DB0021510076309_,1.060554372,0.27821491,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,206373,DB00327,10076309,42,6096,29,4233,1,1.005667481,0.610733526,1.677006192,1,DB0032710076309_,0,0.005651481,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydromorphone,DB00327
,206374,DB00370,10076309,36,4505,27,3636,0.800534778,1.076149586,0.634013277,1.846726546,0.892179633,DB0037010076309_,0.114087785,0.073389473,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,mirtazapine,DB00370
,206375,DB00381,10076309,213,29147,114,22773,0.001152996,1.459813542,1.156635381,1.850422126,0.006197012,DB0038110076309_,5.083688031,0.378308716,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,206376,DB00421,10076309,80,8823,36,5216,0.209386952,1.313713629,0.874596951,2.007910504,0.360439834,DB0042110076309_,1.020430233,0.272857958,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,spironolactone,DB00421
,206377,DB00451,10076309,388,46883,100,15319,0.03475813,1.267774216,1.014325825,1.596980044,0.094960992,DB0045110076309_,2.354289084,0.237262777,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,206378,DB00575,10076309,53,5191,35,3794,0.666036837,1.106779157,0.707205358,1.751506512,0.796884442,DB0057510076309_,0.227045601,0.101454137,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,clonidine,DB00575
,206379,DB01026,10076309,17,1093,38,1030,0.002578779,0.42174081,0.221747914,0.77113854,0.011952602,DB0102610076309_,4.426806243,-0.863364347,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ketoconazole,DB01026
,206381,DB01268,10076309,78,2065,64,3066,0.000511853,1.809270788,1.276885387,2.571581158,0.003147149,DB0126810076309_,5.761258235,0.592923884,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sunitinib,DB01268
,206382,DB09153,10076309,50,7749,28,5671,0.300943358,1.306824456,0.805865245,2.158708346,0.467261818,DB0915310076309_,0.760865539,0.267600115,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium chloride,DB09153
,206386,DB00451,10007586,44,47227,12,15407,0.644579792,1.196179827,0.620856987,2.488576866,0.780593404,DB0045110007586_,0.247700874,0.179133002,NA,10007586,Cardiac murmur,10022891,Investigations,Inv,levothyroxine,DB00451
,206393,DB00331,10000486,29,24917,34,20718,0.205212438,0.709215933,0.416674621,1.199829076,0.355418504,DB0033110000486_,1.034459298,-0.343595239,NA,10000486,Acidosis,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,206395,DB00480,10044055,102,67326,79,67583,0.087264791,1.296061689,0.956506552,1.761603913,0.190542867,DB0048010044055_,1.657878088,0.259330197,NA,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,206396,DB00996,10044055,56,38897,20,22405,0.073384802,1.612811159,0.952515513,2.838339246,0.167165223,DB0099610044055_,1.788772594,0.477978718,NA,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,206409,DB08931,10007882,62,6515,30,2416,0.239128132,0.766415039,0.486696181,1.231136246,0.396870895,DB0893110007882_,0.924144252,-0.26603143,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,riociguat,DB08931
,206416,DB08931,10062244,52,6525,12,2434,0.15781649,1.616438222,0.849672663,3.332851193,0.294553023,DB0893110062244_,1.222296247,0.4802251,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,206440,DB00448,10064848,630,4515,437,2687,0.023387841,0.857985228,0.75117472,0.980569604,0.069762756,DB0044810064848_,2.662654987,-0.153168397,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,lansoprazole,DB00448
,206441,DB00557,10064848,30,5957,22,3045,0.239149253,0.697045817,0.388108278,1.27058243,0.396870895,DB0055710064848_,0.924144252,-0.360904136,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,hydroxyzine,DB00557
,206442,DB00588,10064848,57,16467,37,8431,0.275411071,0.788775072,0.512021766,1.228376546,0.438738182,DB0058810064848_,0.82385244,-0.237274078,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,fluticasone propionate,DB00588
,206443,DB00656,10064848,61,11952,32,6587,0.913586954,1.050575142,0.673360111,1.667559423,0.961305652,DB0065610064848_,0.039462865,0.049337768,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,trazodone,DB00656
,206445,DB01175,10064848,39,10685,14,4878,0.553044856,1.271703812,0.674747784,2.538372007,0.706681123,DB0117510064848_,0.347175743,0.240357585,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,escitalopram,DB01175
,206456,DB00175,10062355,47,8084,25,6081,0.189054718,1.414151036,0.851786779,2.400461357,0.335344553,DB0017510062355_,1.092596759,0.346529377,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,206522,DB00222,10046735,31,3175,20,3108,0.160715032,1.517185376,0.835610808,2.815097452,0.298512145,DB0022210046735_,1.208944661,0.416856892,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,glimepiride,DB00222
,206536,DB00915,10002855,32,1423,28,1023,0.508362375,0.821674369,0.475908837,1.426097948,0.668934342,DB0091510002855_,0.402069367,-0.196411107,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,amantadine,DB00915
,206573,DB00915,10012378,45,1410,21,1030,0.100766268,1.565080139,0.906679496,2.783984777,0.212018519,DB0091510012378_,1.551081654,0.44793703,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,amantadine,DB00915
,206590,DB00490,10027175,57,4013,16,1560,0.293974035,1.38475502,0.781388695,2.59177566,0.459700608,DB0049010027175_,0.777179854,0.325523243,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,buspirone,DB00490
,206606,DB00915,10033371,50,1405,24,1027,0.095552106,1.52258804,0.911425409,2.608580868,0.204077931,DB0091510033371_,1.589253341,0.420411545,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,amantadine,DB00915
,206608,DB00215,10040984,39,11064,13,5263,0.300453737,1.427045005,0.744913642,2.916177705,0.466654444,DB0021510040984_,0.762166245,0.355605876,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,citalopram,DB00215
,206621,DB00169,10049816,69,38622,27,18148,0.445520251,1.200802888,0.759127351,1.950235519,0.613446516,DB0016910049816_,0.488662198,0.182990406,NA,10049816,Muscle tightness,10028395,Musculoskeletal and connective tissue disorders,Musc,cholecalciferol,DB00169
,206663,DB00571,10010774,79,5044,29,2580,0.150979804,1.393336851,0.897306874,2.218482575,0.28526494,DB0057110010774_,1.254336915,0.331701483,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,propranolol,DB00571
,206683,DB00399,10022000,91,6901,74,4924,0.426952738,0.877448184,0.637029574,1.211915565,0.595624166,DB0039910022000_,0.518145405,-0.130737375,NA,10022000,Influenza,10021881,Infections and infestations,Infec,zoledronic acid,DB00399
,206684,DB00668,10022000,137,9954,53,4250,0.577277128,1.103652038,0.796466926,1.548744857,0.726342542,DB0066810022000_,0.319733555,0.098624715,NA,10022000,Influenza,10021881,Infections and infestations,Infec,epinephrine,DB00668
,206689,DB01039,10040753,62,2911,27,3024,0.00010568,2.385115118,1.49033726,3.910597744,0.000836564,DB0103910040753_,7.086207254,0.869247391,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,fenofibrate,DB01039
,206693,DB01069,10008469,52,6648,16,2379,0.679500985,1.162996428,0.652117234,2.186694429,0.806114837,DB0106910008469_,0.215529069,0.150999802,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,206698,DB10708,10037844,40,980,12,443,0.284119457,1.506416521,0.765670505,3.186189214,0.448627635,DB1070810037844_,0.801562056,0.409733665,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,flax seed,DB10708
,206706,DB01373,10066901,49,22671,13,7368,0.65733534,1.224973919,0.653991054,2.462710727,0.790542601,DB0137310066901_,0.235035733,0.202919553,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,206710,DB00669,10040753,120,6257,7,1090,0.00212232,2.986081014,1.400146268,7.607455965,0.01021426,DB0066910040753_,4.583970494,1.09396183,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,sumatriptan,DB00669
,206711,DB01109,10040753,104,4308,33,4237,2.18487761832753e-09,3.099407318,2.071749356,4.746313702,5.66365958557584e-08,DB0110910040753_,16.68661049,1.131210905,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,heparin,DB01109
,206715,DB00863,10008531,128,10545,54,5786,0.118788314,1.300609376,0.93756705,1.825527821,0.239398186,DB0086310008531_,1.429627064,0.262832906,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,206716,DB01156,10008531,88,13534,39,6289,0.848766295,1.04850939,0.71048865,1.572460575,0.924625322,DB0115610008531_,0.078366681,0.047369527,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,206741,DB00484,10015958,95,2412,50,1730,0.086474605,1.362672677,0.951866263,1.97095166,0.189147456,DB0048410015958_,1.665228377,0.309447975,NA,10015958,Eye pain,10015919,Eye disorders,Eye,brimonidine,DB00484
,206742,DB00905,10019211,41,2677,11,914,0.630007127,1.272499493,0.639007645,2.757084075,0.768986386,DB0090510019211_,0.262682013,0.240983071,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,bimatoprost,DB00905
,206751,DB00046,10064848,40,5419,30,4662,0.631051319,1.147059262,0.695493234,1.91047904,0.769921273,DB0004610064848_,0.261467012,0.137201504,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,insulin lispro,DB00046
,206752,DB00047,10064848,80,9205,56,8462,0.121660384,1.313238706,0.920487082,1.88474201,0.243791978,DB0004710064848_,1.411439968,0.27249638,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,insulin glargine,DB00047
,206753,DB00108,10046306,47,10147,10,3285,0.279558993,1.521502771,0.7576903,3.381088063,0.443392025,DB0010810046306_,0.813300968,0.419698511,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,natalizumab,DB00108
,206762,DB00341,10013710,36,11369,32,5036,0.005293543,0.498334768,0.300526305,0.829841369,0.021406273,DB0034110013710_,3.844071251,-0.696483204,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,206763,DB00641,10062237,52,14072,54,12421,0.435794145,0.849989872,0.568998855,1.268663469,0.604334016,DB0064110062237_,0.503628227,-0.162530845,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,simvastatin,DB00641
,206767,DB08910,10019974,58,16686,51,17437,0.388712958,1.188432495,0.80111079,1.767745247,0.558598223,DB0891010019974_,0.582324807,0.172635207,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,206770,DB01234,10021425,52,31573,38,32850,0.113133998,1.423752789,0.918913989,2.224149154,0.230771934,DB0123410021425_,1.466325356,0.353296195,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,dexamethasone,DB01234
,206771,DB01373,10021425,49,22671,12,7369,0.457020609,1.327224342,0.695273513,2.743099576,0.624343652,DB0137310021425_,0.471054338,0.283089801,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,calcium,DB01373
,206779,DB00736,10036018,35,10556,18,5535,1,1.019561557,0.56142173,1.914154689,1,DB0073610036018_,0,0.019372689,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,esomeprazole,DB00736
,206782,DB06404,10049414,42,3027,22,878,0.033786799,0.553845543,0.321216697,0.979779796,0.092945584,DB0640410049414_,2.375741071,-0.590869434,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,human c1-esterase inhibitor,DB06404
,206785,DB08910,10023232,138,16606,85,17403,0.000118268,1.701411045,1.288060768,2.258484798,0.000920545,DB0891010023232_,6.990545037,0.531457933,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,pomalidomide,DB08910
,206787,DB00863,10007515,34,10639,32,5808,0.02840609,0.580028519,0.346899592,0.97203502,0.081175698,DB0086310007515_,2.511139368,-0.544678005,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,ranitidine,DB00863
,206798,DB01015,10005851,16,9871,66,9315,4.85651521273871e-09,0.228803939,0.123538674,0.399876657,1.16952361307226e-07,DB0101510005851_,15.96149915,-1.474889803,male,10005851,Blood urea increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,206805,DB08910,10047571,48,16696,54,17434,0.766273703,0.928151815,0.615445645,1.396157019,0.871285387,DB0891010047571_,0.137785701,-0.074559966,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,pomalidomide,DB08910
,206806,DB08910,10060800,36,16708,24,17464,0.093423953,1.567840391,0.909512649,2.748321474,0.200797138,DB0891010060800_,1.605460146,0.449699125,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,pomalidomide,DB08910
,206807,DB01234,10062244,86,31539,63,32825,0.039929439,1.420725106,1.014214474,1.999575464,0.105537107,DB0123410062244_,2.248692666,0.351167379,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,206832,DB00338,10012671,32,33642,40,22232,0.007745467,0.52869442,0.321352775,0.863379158,0.029027414,DB0033810012671_,3.539514579,-0.63734467,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,omeprazole,DB00338
,206837,DB09038,10012671,268,1980,292,2249,0.652516741,1.042511013,0.870218892,1.248509615,0.786745429,DB0903810012671_,0.239850553,0.041632239,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,empagliflozin,DB09038
,206838,DB09038,10047895,36,2212,65,2476,0.026183798,0.620009674,0.399064211,0.949940347,0.076152249,DB0903810047895_,2.57502066,-0.478020198,NA,10047895,Weight decreased,10022891,Investigations,Inv,empagliflozin,DB09038
,206839,DB00715,10021097,64,4779,63,2224,4.58734248818986e-05,0.472800118,0.32733342,0.683099172,0.000410479,DB0071510021097_,7.798185032,-0.749082562,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,paroxetine,DB00715
,206847,DB08910,10054236,47,16697,51,17437,0.919481805,0.962404002,0.633107248,1.46023694,0.964382416,DB0891010054236_,0.036267366,-0.038320956,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,206854,DB08910,10061818,25,16719,43,17445,0.051642325,0.606653367,0.354910378,1.016450134,0.12812483,DB0891010061818_,2.054750255,-0.49979771,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,206857,DB08910,10061016,41,16703,45,17443,0.829924604,0.951463257,0.60732587,1.486846927,0.910731198,DB0891010061016_,0.093507487,-0.049754209,NA,10061016,Blood test abnormal,10022891,Investigations,Inv,pomalidomide,DB08910
,206859,DB00338,10023547,129,33545,115,22157,0.021654128,0.740943534,0.57141315,0.96169916,0.065846686,DB0033810023547_,2.720426181,-0.299830859,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,omeprazole,DB00338
,206861,DB14500,10023547,48,7761,35,4038,0.132498292,0.713538448,0.451202148,1.138613538,0.259256159,DB1450010023547_,1.349938674,-0.337518957,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,potassium,DB14500
,206873,DB00222,10005555,31,3175,33,3095,0.801886881,0.915749972,0.540966367,1.546580071,0.892815853,DB0022210005555_,0.113374931,-0.088011908,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,glimepiride,DB00222
,206898,DB00331,10039906,136,24810,104,20648,0.558677277,1.088348871,0.836303538,1.419704064,0.711560616,DB0033110039906_,0.34029467,0.08466175,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,metformin,DB00331
,206950,DB01076,10035669,33,25714,61,25522,0.003706859,0.536953923,0.340361264,0.833570125,0.016042217,DB0107610035669_,4.132531441,-0.621842992,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,206967,DB00874,10012174,44,3291,28,1948,0.80637934,0.930169458,0.564209828,1.556931108,0.895314731,DB0087410012174_,0.110579968,-0.072388496,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,guaifenesin,DB00874
,206970,DB00874,10069339,44,3291,39,1937,0.067466082,0.664112753,0.420008404,1.053547967,0.156801446,DB0087410069339_,1.852774948,-0.409303336,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,guaifenesin,DB00874
,206973,DB01234,10039674,33,31592,31,32857,0.708931455,1.107139065,0.657148701,1.869628068,0.826298175,DB0123410039674_,0.190799584,0.101779269,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,206979,DB00927,10038687,32,7465,24,4992,0.683558233,0.891637691,0.508252501,1.583990423,0.808683417,DB0092710038687_,0.212347765,-0.114695404,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,famotidine,DB00927
,206996,DB00007,10037844,44,1903,70,4382,0.064093126,1.44731625,0.965528112,2.149216037,0.150823667,DB0000710037844_,1.891643891,0.369710979,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,leuprolide,DB00007
,206998,DB00924,10022061,69,10093,6,4245,9.76206952776533e-06,4.836669343,2.109955144,13.64474505,0.000106361,DB0092410022061_,9.148671258,1.576226332,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,207004,DB01234,10008111,33,31592,37,32851,0.811345242,0.92746684,0.561929984,1.524749927,0.898588871,DB0123410008111_,0.106929667,-0.075298237,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,207014,DB00175,10060800,36,8095,19,6087,0.222320243,1.424703133,0.7949615,2.632220794,0.376405129,DB0017510060800_,0.977089244,0.353963464,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,pravastatin,DB00175
,207054,DB00370,10007515,74,4467,47,3616,0.198854158,1.274480679,0.869959561,1.883292105,0.347659153,DB0037010007515_,1.056532724,0.242538785,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,mirtazapine,DB00370
,207090,DB00727,10008469,48,3795,48,4125,0.758037523,1.08693281,0.71129931,1.660969121,0.864834475,DB0072710008469_,0.145217149,0.083359794,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,207092,DB06605,10008469,119,13954,58,12975,4.10897542621942e-05,1.907725031,1.381121766,2.660960638,0.000373182,DB0660510008469_,7.893443997,0.645911449,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,207093,DB00727,10020642,51,3792,45,4128,0.355084234,1.233719564,0.807846018,1.889646658,0.524891985,DB0072710020642_,0.644562781,0.210033642,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,nitroglycerin,DB00727
,207096,DB06605,10020642,60,14013,42,12991,0.166047708,1.324365806,0.877407674,2.015393211,0.305491986,DB0660510020642_,1.185831733,0.280933708,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,apixaban,DB06605
,207110,DB00126,10017413,73,10098,54,5891,0.196546674,0.788672804,0.546317965,1.144652472,0.344805987,DB0012610017413_,1.064773378,-0.237403742,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,ascorbic acid,DB00126
,207113,DB00451,10017413,281,46990,97,15322,0.631900646,0.944588688,0.746784377,1.203379401,0.770695641,DB0045110017413_,0.260461743,-0.057005697,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,levothyroxine,DB00451
,207130,DB00273,10061623,42,8439,16,2177,0.192168661,0.677196681,0.37199995,1.292841869,0.339390798,DB0027310061623_,1.080603039,-0.38979353,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,207134,DB05676,10013700,130,46999,36,25293,0.000230554,1.943339671,1.334028703,2.895920616,0.001622734,DB0567610013700_,6.423642944,0.664407973,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,apremilast,DB05676
,207140,DB00051,10049187,40,25691,14,11406,0.555063259,1.268445206,0.675299939,2.525054932,0.708551559,DB0005110049187_,0.34453245,0.237791903,NA,10049187,Red blood cell sedimentation rate increased,10022891,Investigations,Inv,adalimumab,DB00051
,207145,DB00136,10003988,33,2059,27,1655,1,0.982408547,0.570230919,1.705957321,1,DB0013610003988_,0,-0.017748022,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,calcitriol,DB00136
,207180,DB00285,10076309,96,10855,42,3676,0.169297308,0.774061936,0.532197935,1.142806552,0.309973512,DB0028510076309_,1.17126843,-0.256103388,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,207181,DB00734,10076309,59,3991,64,4838,0.584448738,1.117507274,0.769018372,1.621537442,0.732249818,DB0073410076309_,0.311633541,0.111100557,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,207185,DB00158,10022687,41,16774,18,8086,0.782846421,1.098008621,0.616407875,2.031888861,0.881806742,DB0015810022687_,0.12578236,0.093498195,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,207190,DB00471,10022687,39,14150,14,5451,0.879326149,1.073135482,0.56948665,2.141521923,0.949348846,DB0047110022687_,0.051978954,0.070584721,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,montelukast,DB00471
,207192,DB00588,10022687,43,16481,30,8438,0.215396287,0.733822241,0.449453298,1.212512045,0.367869232,DB0058810022687_,1.000027751,-0.309488459,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,fluticasone propionate,DB00588
,207231,DB00115,10020751,221,18204,62,10410,2.05081154259768e-07,2.038329432,1.529858727,2.749870154,3.46994408736274e-06,DB0011510020751_,12.57137208,0.712130567,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,cyanocobalamin,DB00115
,207232,DB00399,10020751,56,6936,27,4971,0.094555192,1.48643085,0.921807581,2.451365786,0.202564108,DB0039910020751_,1.596698858,0.396377844,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,zoledronic acid,DB00399
,207333,DB01136,10051398,22,9862,56,11059,0.000874936,0.440573042,0.255937121,0.733810941,0.004935659,DB0113610051398_,5.311269154,-0.819679031,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,carvedilol,DB01136
,207335,DB01276,10037087,58,1959,18,1493,0.000597183,2.455126834,1.418880479,4.447486597,0.003582143,DB0127610037087_,5.631794142,0.898178424,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,exenatide,DB01276
,207341,DB01276,10022081,117,1900,90,1421,0.884937469,0.972259518,0.725759507,1.305973172,0.952079302,DB0127610022081_,0.049106947,-0.028132517,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,207363,DB01281,10020937,54,8878,13,1785,0.514642233,0.835201518,0.448612207,1.671930037,0.67450623,DB0128110020937_,0.393774367,-0.180082244,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,abatacept,DB01281
,207364,DB00065,10022000,42,9422,17,4940,0.411889831,1.295353474,0.720859816,2.429670083,0.581328475,DB0006510022000_,0.54243932,0.258783611,NA,10022000,Influenza,10021881,Infections and infestations,Infec,infliximab,DB00065
,207365,DB01281,10022000,88,8844,6,1792,0.005024244,2.971614633,1.309094061,8.329582673,0.020543245,DB0128110022000_,3.885223121,1.089105453,female,10022000,Influenza,10021881,Infections and infestations,Infec,abatacept,DB01281
,207381,DB00281,10050584,92,11366,19,5652,0.000233123,2.407742025,1.456075133,4.184575784,0.001637314,DB0028110050584_,6.414698083,0.878689389,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,lidocaine,DB00281
,207412,DB01015,10001760,74,9813,19,9362,2.7017928249197e-08,3.715277368,2.218521801,6.520051496,5.49877076291246e-07,DB0101510001760_,14.41357108,1.312453337,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,sulfamethoxazole,DB01015
,207413,DB09270,10001760,55,3059,6,2362,1.38138230012908e-08,7.075864555,3.044331586,20.14594302,3.00701597955759e-07,DB0927010001760_,15.01714743,1.956689635,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,ubidecarenone,DB09270
,207414,DB01062,10003239,102,4384,31,1714,0.242295144,1.286333656,0.849430003,1.998153819,0.400531894,DB0106210003239_,0.914961879,0.251796044,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,oxybutynin,DB01062
,207422,DB00281,10006002,40,11418,15,5656,0.3924572,1.320973964,0.713226531,2.576422542,0.562362103,DB0028110006002_,0.575609325,0.278369316,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lidocaine,DB00281
,207441,DB01373,10012374,53,22667,10,7371,0.141349001,1.723393607,0.867162802,3.802105887,0.271760983,DB0137310012374_,1.302832337,0.544295374,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,calcium,DB01373
,207446,DB00381,10014062,39,29321,25,22862,0.528842815,1.216349013,0.717521189,2.097851842,0.686168703,DB0038110014062_,0.376631759,0.19585376,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,207452,DB09270,10016322,72,3042,38,2330,0.065372064,1.451163675,0.962529374,2.218731944,0.153078369,DB0927010016322_,1.876805272,0.372365769,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,207455,DB01373,10016334,70,22650,12,7369,0.039146806,1.897700094,1.020091907,3.849593175,0.103921002,DB0137310016334_,2.26412426,0.640642676,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,207500,DB00126,10031009,36,10135,15,5930,0.310234714,1.404214391,0.749096872,2.763023427,0.477640618,DB0012610031009_,0.738896675,0.339477994,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,ascorbic acid,DB00126
,207501,DB01015,10031009,31,9856,19,9362,0.156364091,1.549759838,0.847585872,2.905695829,0.292518425,DB0101510031009_,1.229227624,0.438099975,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,207515,DB01015,10042128,70,9817,54,9327,0.279572293,1.231578643,0.850207302,1.792518729,0.443392025,DB0101510042128_,0.813300968,0.208296796,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,sulfamethoxazole,DB01015
,207516,DB01098,10042128,57,8092,18,7191,6.10775227700974e-05,2.813753302,1.630246679,5.086167771,0.000523621,DB0109810042128_,7.554741982,1.034519287,female,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,207521,DB00264,10044034,94,29513,49,24843,0.00695525,1.614795696,1.130957337,2.330877677,0.026664459,DB0026410044034_,3.624423741,0.479208445,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,207561,DB00126,10061224,39,10132,20,5925,0.686757808,1.140336814,0.64841907,2.065510416,0.81105262,DB0012610061224_,0.209422344,0.13132367,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,ascorbic acid,DB00126
,207609,DB14500,10000060,68,7741,33,4040,0.833324351,1.075422051,0.698296882,1.686104294,0.913407226,DB1450010000060_,0.090573467,0.07271319,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,potassium,DB14500
,207639,DB00526,10051398,21,1577,33,1861,0.337180607,0.75102737,0.411133956,1.343559284,0.506329539,DB0052610051398_,0.680567559,-0.286313183,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,oxaliplatin,DB00526
,207645,DB00451,10022972,65,47206,20,15399,0.900061824,1.06015852,0.633714838,1.848607212,0.95659897,DB0045110022972_,0.044371025,0.058418444,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,levothyroxine,DB00451
,207676,DB08875,10033553,34,609,47,1196,0.149959501,1.420451481,0.875881031,2.282602875,0.283850176,DB0887510033553_,1.259308729,0.350974766,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,cabozantinib,DB08875
,207682,DB01592,10043554,39,6237,25,3042,0.287631778,0.760918476,0.448042308,1.314439499,0.452583137,DB0159210043554_,0.792783806,-0.273229054,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,iron,DB01592
,207704,DB00863,10005191,52,10621,15,5825,0.028883876,1.901197455,1.052949424,3.639448772,0.082224052,DB0086310005191_,2.498307413,0.642483927,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,207706,DB01175,10020642,97,10627,55,4837,0.218329343,0.802775152,0.569721554,1.140870169,0.371526675,DB0117510020642_,0.990134613,-0.219680615,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,escitalopram,DB01175
,207708,DB00193,10029410,42,19278,32,8670,0.031590428,0.590287668,0.363602197,0.966787903,0.088213578,DB0019310029410_,2.427994381,-0.527145289,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,tramadol,DB00193
,207711,DB00230,10049040,42,19632,20,8631,0.783064732,0.923247772,0.529740487,1.66096113,0.881832675,DB0023010049040_,0.125752951,-0.079857638,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,pregabalin,DB00230
,207777,DB01067,10069339,93,4268,134,4689,0.050854408,0.762513633,0.576939919,1.004312814,0.126624177,DB0106710069339_,2.066531816,-0.271134892,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,glipizide,DB01067
,207779,DB01222,10069339,98,9176,93,5312,0.000847952,0.610075752,0.453666626,0.820865342,0.004804574,DB0122210069339_,5.338186904,-0.494172146,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,budesonide,DB01222
,207820,DB06643,10050256,71,52350,7,7508,0.491548649,1.45467268,0.670170444,3.750113951,0.654642731,DB0664310050256_,0.423665642,0.374780913,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,207831,DB00203,10051301,51,13827,22,8916,0.119724226,1.494796516,0.889693767,2.590261083,0.240970273,DB0020310051301_,1.4230817,0.401990088,NA,10051301,Exercise tolerance decreased,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,207840,DB00390,10019303,65,4080,21,3280,0.000171701,2.487992847,1.497467524,4.294866149,0.001268099,DB0039010019303_,6.670236713,0.9114763,NA,10019303,Heart rate increased,10022891,Investigations,Inv,digoxin,DB00390
,207841,DB01222,10019303,68,9206,29,5376,0.170384512,1.369273734,0.873199224,2.197014885,0.311389321,DB0122210019303_,1.166711314,0.314280478,NA,10019303,Heart rate increased,10022891,Investigations,Inv,budesonide,DB01222
,207842,DB00390,10076309,38,4107,22,3279,0.243025584,1.378982374,0.793268525,2.452974387,0.401327352,DB0039010076309_,0.912977845,0.321345817,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,digoxin,DB00390
,207870,DB09053,10047942,42,2243,75,3977,1,0.992921227,0.661348979,1.473447103,1,DB0905310047942_,0,-0.007103947,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,ibrutinib,DB09053
,207874,DB00586,10039073,120,6989,28,2777,0.009903914,1.702810022,1.117882644,2.676032193,0.035279087,DB0058610039073_,3.344464921,0.532279841,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,207883,DB00497,10028116,36,19231,22,16353,0.237376041,1.391459539,0.796332023,2.483931269,0.394756872,DB0049710028116_,0.929485218,0.330353224,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,207926,DB05679,10027599,48,6883,11,4898,0.000278364,3.104906391,1.588065907,6.638412044,0.001899728,DB0567910027599_,6.266044588,1.132983567,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,ustekinumab,DB05679
,207932,DB00046,10022086,70,5389,33,4659,0.003835407,1.83375995,1.193434922,2.869862862,0.016488989,DB0004610022086_,4.105062456,0.606368477,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,207935,DB00338,10013654,24,33650,44,22228,5.16199883777219e-05,0.360313747,0.209496322,0.605797806,0.000453714,DB0033810013654_,7.698043752,-1.020780108,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,207936,DB00829,10013654,361,7691,511,3943,1.84852051546976e-46,0.36221617,0.313940922,0.417597634,9.43463334934419e-44,DB0082910013654_,99.06935677,-1.015514091,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,207992,DB00065,10022095,44,9420,6,4951,0.000485676,3.853920361,1.634800885,11.07462925,0.003018679,DB0006510022095_,5.802936089,1.349090906,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,207999,DB00213,10028735,142,18753,39,13382,1.47557768914658e-08,2.5981131,1.810364318,3.807439968,3.18498274942008e-07,DB0021310028735_,14.95964878,0.954785451,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,208002,DB00193,10062244,57,19263,10,8692,0.003386647,2.571926225,1.300949865,5.651794192,0.014914636,DB0019310062244_,4.205412244,0.944655122,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,208003,DB00213,10062244,59,18836,19,13402,0.001796322,2.209359234,1.297816216,3.926380845,0.00890513,DB0021310062244_,4.721127756,0.792702534,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,208005,DB00761,10062244,60,15247,29,8596,0.580427782,1.166420168,0.736338733,1.886535448,0.728953804,DB0076110062244_,0.316144919,0.153939373,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium chloride,DB00761
,208021,DB00512,10046571,72,4665,25,5073,1.90136331647862e-07,3.131546692,1.958508146,5.162099721,3.24528147880783e-06,DB0051210046571_,12.63830847,1.141527033,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,vancomycin,DB00512
,208080,DB00745,10037844,55,2522,14,1069,0.109167413,1.664996039,0.908627432,3.256851725,0.224782849,DB0074510037844_,1.492620457,0.509822744,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,modafinil,DB00745
,208123,DB00264,10076309,212,29395,152,24740,0.139426773,1.173861936,0.947946312,1.456457705,0.269041098,DB0026410076309_,1.312891129,0.160299113,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,208125,DB13961,10076309,68,9389,34,6380,0.156906732,1.359010971,0.886562716,2.118695479,0.293326507,DB1396110076309_,1.226468932,0.306757208,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fish oil,DB13961
,208131,DB00996,10076308,199,38754,121,22304,0.641745723,0.946530288,0.750861316,1.197274031,0.778362657,DB0099610076308_,0.250562723,-0.054952308,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,208158,DB00877,10013710,26,1082,41,1390,0.455438354,0.814726519,0.475249627,1.373938544,0.622899661,DB0087710013710_,0.473369831,-0.204902782,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,sirolimus,DB00877
,208161,DB14126,10028813,50,921,41,1235,0.023243954,1.634887001,1.050142371,2.55790561,0.069447834,DB1412610028813_,2.667179401,0.49157369,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,tenofovir,DB14126
,208164,DB00877,10047700,38,1070,34,1397,0.118285124,1.458966325,0.887583302,2.406710355,0.238669806,DB0087710047700_,1.432674246,0.377728189,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sirolimus,DB00877
,208190,DB00635,10019851,23,33030,37,23757,0.002374097,0.447107031,0.253570613,0.772866983,0.011190377,DB0063510019851_,4.492701108,-0.804957271,NA,10019851,Hepatotoxicity,10019805,Hepatobiliary disorders,Hepat,prednisone,DB00635
,208196,DB06605,10069339,166,13907,171,12862,0.351070362,0.897819427,0.719757777,1.119725927,0.520805061,DB0660510069339_,0.652379471,-0.107786314,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,apixaban,DB06605
,208243,DB00334,10069339,42,2807,83,2729,0.000184676,0.492025849,0.329805467,0.724482143,0.001348389,DB0033410069339_,6.60884471,-0.709224025,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,olanzapine,DB00334
,208244,DB00455,10069339,89,9312,88,5030,9.35185278482573e-05,0.546304009,0.401436108,0.743616219,0.000753567,DB0045510069339_,7.190693052,-0.604579666,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,loratadine,DB00455
,208279,DB00465,10021097,40,2064,15,868,0.767443961,1.121401493,0.602329964,2.197207615,0.872238704,DB0046510021097_,0.136692149,0.114579236,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,ketorolac,DB00465
,208283,DB11074,10021097,30,1230,37,831,0.016346227,0.547967093,0.324158251,0.919549718,0.052693229,DB1107410021097_,2.94326832,-0.601540043,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,dimethicone,DB11074
,208284,DB00181,10069339,89,9767,89,5782,0.000575267,0.59204076,0.435457539,0.804846474,0.003469688,DB0018110069339_,5.663690531,-0.524179794,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,baclofen,DB00181
,208285,DB00196,10069339,94,4989,157,3128,4.49271516603804e-14,0.375433192,0.286448712,0.489885415,2.40022394592093e-12,DB0019610069339_,26.75545907,-0.97967474,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,fluconazole,DB00196
,208286,DB00281,10069339,102,11356,97,5574,4.64612610450278e-06,0.51614587,0.386306477,0.690076171,5.54728251904863e-05,DB0028110069339_,9.799617293,-0.66136586,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,lidocaine,DB00281
,208287,DB00295,10069339,168,14495,231,9371,1.2300033075472e-13,0.470189496,0.382457058,0.577099256,6.19954687226808e-12,DB0029510069339_,25.80654491,-0.754619483,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,morphine,DB00295
,208288,DB00327,10069339,99,6039,108,4154,0.00126317,0.630585593,0.473722961,0.838579491,0.006665147,DB0032710069339_,5.010863305,-0.461106379,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,hydromorphone,DB00327
,208289,DB00465,10069339,47,2057,29,854,0.099075372,0.672953656,0.411693106,1.116802365,0.209457284,DB0046510069339_,1.563235457,-0.396078814,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ketorolac,DB00465
,208291,DB00497,10069339,259,19008,356,16019,2.21305695711173e-09,0.61314094,0.519672269,0.722621062,5.72823260636945e-08,DB0049710069339_,16.67527371,-0.48916045,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,oxycodone,DB00497
,208292,DB00502,10069339,25,1369,50,1822,0.099923161,0.66553008,0.392413685,1.102697003,0.210657707,DB0050210069339_,1.557520703,-0.407171442,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,haloperidol,DB00502
,208293,DB00684,10069339,79,2713,56,2292,0.336509246,1.191760257,0.831528694,1.717768966,0.505552442,DB0068410069339_,0.682103503,0.175431422,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,tobramycin,DB00684
,208295,DB00916,10069339,63,5260,81,2350,5.10097667934285e-10,0.347539204,0.245068703,0.490970779,1.49391835115907e-08,DB0091610069339_,18.01927831,-1.056877803,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,metronidazole,DB00916
,208296,DB01075,10069339,146,19802,153,10944,5.27735241636634e-08,0.527380085,0.416955429,0.666834066,1.01622863197208e-06,DB0107510069339_,13.7994122,-0.639833767,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,diphenhydramine,DB01075
,208297,DB01141,10069339,24,374,44,561,0.52131215,0.818342648,0.467536598,1.402208419,0.680135498,DB0114110069339_,0.38546324,-0.200474145,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,micafungin,DB01141
,208298,DB01229,10069339,118,5623,56,2653,1,0.994176362,0.71480446,1.39688815,1,DB0122910069339_,0,-0.005840662,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,paclitaxel,DB01229
,208334,DB00996,10052302,38,38915,21,22404,1,1.041774201,0.595894796,1.868923664,1,DB0099610052302_,0,0.040925222,NA,10052302,Impaired work ability,10041244,Social circumstances,SocCi,gabapentin,DB00996
,208336,DB00612,10012735,70,1070,33,607,0.459142013,1.203180738,0.774313309,1.902735576,0.626498187,DB0061210012735_,0.467609399,0.184968665,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,bisoprolol,DB00612
,208339,DB00612,10035664,31,1109,25,615,0.202346879,0.687826703,0.389055294,1.227033779,0.35174187,DB0061210035664_,1.044857697,-0.374218357,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,bisoprolol,DB00612
,208345,DB00193,10047340,81,19239,29,8673,0.303820158,1.259100934,0.814019974,1.997948796,0.470368291,DB0019310047340_,0.754239292,0.230397922,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,tramadol,DB00193
,208366,DB06403,10047340,48,21423,6,6655,0.035546552,2.485213502,1.061316821,7.1094913,0.096585586,DB0640310047340_,2.337325766,0.910358572,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,ambrisentan,DB06403
,208367,DB00370,10054112,63,4478,47,3616,0.700536943,1.082412975,0.728116059,1.618805036,0.819968095,DB0037010054112_,0.198489848,0.079192785,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,mirtazapine,DB00370
,208368,DB00404,10054112,159,19733,51,9811,0.006350225,1.550033766,1.123044992,2.170905313,0.024783319,DB0040410054112_,3.697584479,0.438276715,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,alprazolam,DB00404
,208371,DB06724,10054112,59,7870,35,3884,0.381029553,0.831960151,0.537547447,1.304872628,0.551051544,DB0672410054112_,0.595926929,-0.183970734,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,calcium carbonate,DB06724
,208373,DB13961,10054112,62,9395,34,6380,0.348600794,1.238305052,0.80129479,1.943165702,0.518129058,DB1396110054112_,0.657530921,0.213743551,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,fish oil,DB13961
,208379,DB00482,10006002,41,8218,10,3061,0.270342455,1.52702848,0.751095044,3.422796345,0.433026787,DB0048210006002_,0.83695569,0.423323677,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,208395,DB09037,10040047,23,2503,32,2803,0.497796315,0.804929912,0.448466553,1.423521614,0.659887341,DB0903710040047_,0.415686155,-0.217000071,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,pembrolizumab,DB09037
,208396,DB09037,10060933,73,2453,104,2731,0.125522698,0.78150945,0.568353385,1.070006184,0.249394469,DB0903710060933_,1.388719425,-0.246528037,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,pembrolizumab,DB09037
,208397,DB00203,10015958,56,13822,13,8925,0.00045228,2.781388336,1.501149964,5.547165691,0.002841006,DB0020310015958_,5.863597038,1.022950204,female,10015958,Eye pain,10015919,Eye disorders,Eye,sildenafil,DB00203
,208405,DB01273,10074903,38,2002,18,1257,0.406035225,1.325396384,0.734304101,2.478531418,0.575608008,DB0127310074903_,0.552328391,0.281711572,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,varenicline,DB01273
,208417,DB00472,10033664,43,10716,14,4298,0.559338146,1.231865777,0.660252122,2.440622821,0.712094248,DB0047210033664_,0.339545005,0.208529912,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,208424,DB00682,10069802,61,19398,12,16352,1.92150451376607e-07,4.284890516,2.283266134,8.7466734,3.2754050677264e-06,DB0068210069802_,12.62906901,1.455095001,female,10069802,Device related sepsis,10021881,Infections and infestations,Infec,warfarin,DB00682
,208426,DB00169,10067482,84,38607,34,18141,0.490740443,1.160889234,0.770484587,1.784551611,0.653947405,DB0016910067482_,0.424728352,0.149186293,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,208448,DB01592,10013911,43,6233,25,3042,0.517446916,0.839470514,0.500172131,1.437092316,0.677029315,DB0159210013911_,0.390040705,-0.174983926,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,iron,DB01592
,208457,DB01373,10040844,100,22620,22,7359,0.113021728,1.478730086,0.924195422,2.466857413,0.230587659,DB0137310040844_,1.467124188,0.391183669,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,208460,DB13961,10040844,53,9404,34,6380,0.827486326,1.057564064,0.673916212,1.680003991,0.909224901,DB1396110040844_,0.0951628,0.055968211,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,fish oil,DB13961
,208462,DB00863,10042128,72,10601,28,5812,0.141673901,1.409758272,0.898375016,2.268994986,0.272105403,DB0086310042128_,1.301565776,0.343418251,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,208476,DB00559,10022595,40,9619,14,3292,1,0.977827456,0.519990783,1.948415281,1,DB0055910022595_,0,-0.02242205,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,bosentan,DB00559
,208488,DB01240,10044565,49,5702,18,1558,0.295576739,0.74384591,0.42421595,1.360834304,0.461434529,DB0124010044565_,0.7734151,-0.295921376,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,epoprostenol,DB01240
,208489,DB09037,10021036,29,2497,30,2805,0.793892696,1.085877502,0.626952034,1.878097006,0.888291402,DB0903710021036_,0.118455435,0.082388417,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,pembrolizumab,DB09037
,208501,DB00316,10007625,38,65436,29,36924,0.25184986,0.739421299,0.444015521,1.243297213,0.411910373,DB0031610007625_,0.886949495,-0.301887427,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,208507,DB00563,10072850,44,46602,13,15335,0.878044591,1.11374923,0.588999469,2.254561449,0.948345163,DB0056310072850_,0.053036747,0.107732008,NA,10072850,Sensitivity to weather change,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,208508,DB06655,10046735,36,3652,14,2105,0.239543357,1.482067627,0.777943199,2.981847239,0.397361846,DB0665510046735_,0.922907963,0.393438158,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,liraglutide,DB06655
,208650,DB00316,10015488,38,65436,17,36936,0.483997519,1.261764348,0.695014103,2.384285134,0.648215366,DB0031610015488_,0.433532283,0.232511017,NA,10015488,Essential hypertension,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,208661,DB00571,10017885,44,5079,12,2597,0.064042346,1.874708529,0.971230763,3.906449625,0.150716544,DB0057110017885_,1.892354401,0.628453196,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,propranolol,DB00571
,208678,DB00571,10027599,91,5032,13,2596,9.81196884821513e-07,3.610831748,2.0046659,7.053897662,1.40674253741736e-05,DB0057110027599_,11.17164869,1.283938147,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,propranolol,DB00571
,208679,DB01098,10027599,56,8093,11,7198,2.10514380024556e-07,4.527433366,2.344601121,9.59186732,3.5550083385451e-06,DB0109810027599_,12.54715315,1.510155193,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,208724,DB05259,10019303,98,11172,17,2711,0.236947166,1.398827452,0.828828388,2.502329447,0.394299405,DB0525910019303_,0.930644746,0.335634352,NA,10019303,Heart rate increased,10022891,Investigations,Inv,glatiramer,DB05259
,208760,DB00381,10051792,39,29321,36,22851,0.48603507,0.84428934,0.522647286,1.367293822,0.649960453,DB0038110051792_,0.430843759,-0.169260024,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,208816,DB01234,10013774,114,31511,51,32837,1.97948919425611e-07,2.329335832,1.659545464,3.308897511,3.36116753688772e-06,DB0123410013774_,12.60322216,0.845583176,NA,10013774,Dry eye,10015919,Eye disorders,Eye,dexamethasone,DB01234
,208821,DB00338,10015946,58,33616,33,22239,0.521640786,1.162699205,0.745454335,1.841313604,0.680376182,DB0033810015946_,0.385109425,0.150744203,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,omeprazole,DB00338
,208831,DB01234,10015946,52,31573,32,32856,0.021382264,1.691007509,1.067926535,2.715443613,0.065189679,DB0123410015946_,2.730454115,0.52532451,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,dexamethasone,DB01234
,208835,DB00869,10016256,46,1259,39,890,0.433311419,0.833864716,0.527439684,1.324065585,0.601795976,DB0086910016256_,0.507836802,-0.181684101,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dorzolamide,DB00869
,208907,DB00112,10047654,72,5861,50,4041,1,0.992840605,0.680946559,1.457494104,1,DB0011210047654_,0,-0.007185147,NA,10047654,Vitreous floaters,10015919,Eye disorders,Eye,bevacizumab,DB00112
,208919,DB01270,10047654,76,1182,65,904,0.539703771,0.894280343,0.626137217,1.28015431,0.69546591,DB0127010047654_,0.363173285,-0.11173597,NA,10047654,Vitreous floaters,10015919,Eye disorders,Eye,ranibizumab,DB01270
,208925,DB00316,10052140,62,65412,26,36927,0.222723213,1.346181756,0.838806752,2.2180159,0.376856651,DB0031610052140_,0.9758904,0.297272256,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,acetaminophen,DB00316
,208934,DB01234,10052140,51,31574,19,32869,6.18688105135607e-05,2.79431907,1.621107062,5.012808457,0.000529111,DB0123410052140_,7.544312917,1.027588453,female,10052140,Eye pruritus,10015919,Eye disorders,Eye,dexamethasone,DB01234
,208979,DB00112,10076309,57,5876,26,4065,0.092060105,1.516570524,0.936305464,2.517313041,0.198522454,DB0011210076309_,1.616853065,0.416451551,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,bevacizumab,DB00112
,208981,DB00563,10076309,206,46440,82,15266,0.150600763,0.825803752,0.635921466,1.080886894,0.284757154,DB0056310076309_,1.256118555,-0.191398122,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,208982,DB00620,10076309,68,4760,28,3104,0.045409671,1.583585691,1.003338541,2.560917126,0.116357303,DB0062010076309_,2.151089626,0.459691701,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,triamcinolone,DB00620
,208985,DB01039,10076309,32,2941,31,3020,0.899361333,1.060002261,0.62454588,1.801201745,0.956490275,DB0103910076309_,0.044484657,0.058271041,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fenofibrate,DB01039
,208986,DB01065,10076309,47,4284,24,3027,0.226164111,1.383664381,0.827116726,2.371169646,0.381041635,DB0106510076309_,0.964846633,0.324735328,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,melatonin,DB01065
,208988,DB01104,10076309,109,15354,55,7231,0.675137145,0.933345875,0.66805033,1.317000087,0.80302185,DB0110410076309_,0.219373356,-0.068979434,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,209043,DB00047,10028735,46,9239,23,8495,0.015803412,1.838875389,1.090890743,3.181637083,0.051355962,DB0004710028735_,2.968974251,0.609154183,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,209068,DB00489,10028813,61,1022,33,1101,0.001510967,1.990748541,1.27076423,3.167527522,0.007741112,DB0048910028813_,4.861209874,0.688510719,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sotalol,DB00489
,209069,DB05676,10037660,180,46949,85,25244,0.333873694,1.138624772,0.874562056,1.492359056,0.502924469,DB0567610037660_,0.687315282,0.129821194,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,209091,DB00169,10005654,43,38648,17,18158,0.583043748,1.188376088,0.66361851,2.223169239,0.731134245,DB0016910005654_,0.31315819,0.172587743,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,209099,DB00126,10005724,52,10119,21,5924,0.180793264,1.449612567,0.857150225,2.536408462,0.324866758,DB0012610005724_,1.124340156,0.371296325,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,ascorbic acid,DB00126
,209104,DB06724,10005724,61,7868,17,3902,0.039361476,1.779446201,1.024265488,3.254559965,0.104369969,DB0672410005724_,2.259813299,0.576302193,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,calcium carbonate,DB06724
,209107,DB00169,10019075,34,38657,24,18151,0.123784753,0.665177154,0.382898009,1.172800982,0.24677802,DB0016910019075_,1.399266052,-0.407701877,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,209127,DB00335,10049848,62,8404,41,5424,0.919529553,0.975971603,0.646334281,1.487720866,0.964382416,DB0033510049848_,0.036267366,-0.024321789,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,209155,DB00126,10069339,124,10047,115,5830,0.000421158,0.625733227,0.480523468,0.815323856,0.002672977,DB0012610069339_,5.924562632,-0.468831154,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ascorbic acid,DB00126
,209156,DB00476,10069339,135,17122,83,6094,0.000142743,0.578917201,0.436481254,0.77165875,0.001081043,DB0047610069339_,6.829828579,-0.546595815,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,duloxetine,DB00476
,209157,DB00582,10069339,59,1071,67,1507,0.267032337,1.238975702,0.850213773,1.801662523,0.429319529,DB0058210069339_,0.845553813,0.214284992,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,voriconazole,DB00582
,209158,DB00681,10069339,33,380,57,585,0.652721905,0.891342219,0.551113842,1.422163101,0.786900669,DB0068110069339_,0.239653254,-0.115026841,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,amphotericin b,DB00681
,209178,DB00046,10035528,31,5428,29,4663,0.795603306,0.918318003,0.534516309,1.581900712,0.889335739,DB0004610035528_,0.117280456,-0.08521154,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,insulin lispro,DB00046
,209180,DB00472,10035528,41,10718,15,4297,0.882458258,1.095824662,0.593114071,2.133661176,0.950859822,DB0047210035528_,0.050388628,0.091507196,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,fluoxetine,DB00472
,209187,DB00635,10051608,35,33018,18,23776,0.267359948,1.400169741,0.771599994,2.626755161,0.42963729,DB0063510051608_,0.844813938,0.336593473,NA,10051608,Platelet count increased,10022891,Investigations,Inv,prednisone,DB00635
,209192,DB01101,10048959,123,7466,50,3858,0.169289658,1.271203481,0.905704169,1.807530527,0.309970302,DB0110110048959_,1.171278786,0.239964075,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,209195,DB00654,10020772,38,3778,30,2568,0.537577815,0.861008257,0.517973707,1.443073013,0.693745088,DB0065410020772_,0.365650695,-0.149651184,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,latanoprost,DB00654
,209230,DB09038,10019211,37,2211,39,2502,0.817060578,1.073545631,0.663225358,1.735020547,0.902124936,DB0903810019211_,0.103002258,0.070966844,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,empagliflozin,DB09038
,209232,DB08908,10066901,108,10565,28,3251,0.477185378,1.186880305,0.775537821,1.872246744,0.642573878,DB0890810066901_,0.442273483,0.171328272,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,dimethyl fumarate,DB08908
,209235,DB06724,10003553,50,7879,7,3912,0.00056384,3.546125492,1.598164158,9.278748846,0.003409375,DB0672410003553_,5.681226427,1.265855597,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,209239,DB00047,10031252,30,9255,38,8480,0.223676889,0.723381683,0.432405143,1.20017153,0.378113493,DB0004710031252_,0.972560882,-0.323818281,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,209248,DB00215,10069339,132,10971,72,5204,0.3656117,0.869641758,0.64638284,1.177941306,0.535202915,DB0021510069339_,0.625109323,-0.139673925,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,citalopram,DB00215
,209249,DB00231,10069339,38,3258,49,2090,0.001289787,0.497545111,0.315736104,0.778842126,0.006782444,DB0023110069339_,4.993417772,-0.698069052,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,temazepam,DB00231
,209252,DB00950,10069339,48,4670,29,2027,0.17070571,0.718451186,0.442482588,1.185258515,0.311807027,DB0095010069339_,1.165370785,-0.330657515,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,fexofenadine,DB00950
,209253,DB00973,10069339,43,3808,46,2975,0.162055919,0.730340439,0.469105556,1.135045789,0.300112011,DB0097310069339_,1.203599503,-0.314244499,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ezetimibe,DB00973
,209271,DB01212,10003658,21,1998,35,1906,0.044094724,0.57245617,0.315414691,1.015330013,0.113769797,DB0121210003658_,2.173578196,-0.557819106,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ceftriaxone,DB01212
,209272,DB00758,10018830,28,8272,58,10016,0.022064262,0.584557285,0.358087616,0.933894154,0.066783741,DB0075810018830_,2.706295623,-0.536900496,NA,10018830,Haematemesis,10017947,Gastrointestinal disorders,Gastr,clopidogrel,DB00758
,209292,DB00047,10013710,41,9244,52,8466,0.120003919,0.722119943,0.467020248,1.109959395,0.241392402,DB0004710013710_,1.421331444,-0.325564028,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,209309,DB00646,10007559,31,3422,21,1979,0.566644467,0.853737142,0.473653956,1.567852811,0.717985481,DB0064610007559_,0.331305931,-0.158131929,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,nystatin,DB00646
,209329,DB00421,10063743,30,8873,21,5231,0.563186842,0.842219279,0.465834002,1.549496295,0.715259399,DB0042110063743_,0.335110006,-0.171714872,NA,10063743,Hypophagia,10027433,Metabolism and nutrition disorders,Metab,spironolactone,DB00421
,209336,DB00231,10017955,27,3269,33,2106,0.016181452,0.527152198,0.303954771,0.9070106,0.052294012,DB0023110017955_,2.950873408,-0.640265972,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,temazepam,DB00231
,209345,DB00658,10013573,32,1271,21,1375,0.094963147,1.648178533,0.916095701,3.024483177,0.203150185,DB0065810013573_,1.593809748,0.499670758,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sevelamer,DB00658
,209348,DB01062,10039906,62,4424,10,1735,0.005484802,2.431169582,1.23386558,5.331339972,0.0220272,DB0106210039906_,3.815477231,0.888372451,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,oxybutynin,DB01062
,209350,DB01062,10046543,52,4434,9,1736,0.021120499,2.26187454,1.101385421,5.232836572,0.06454171,DB0106210046543_,2.7404436,0.816193912,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,oxybutynin,DB01062
,209354,DB00695,10000381,43,28006,22,20506,0.208665044,1.431106933,0.837073151,2.512804962,0.359715407,DB0069510000381_,1.022442096,0.358448224,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,209358,DB00046,10001053,28,5431,36,4656,0.130700232,0.666822869,0.391287625,1.125681574,0.256760508,DB0004610001053_,1.359611506,-0.405230832,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin lispro,DB00046
,209362,DB01202,10001053,25,6689,30,5688,0.223348048,0.708651915,0.399138791,1.248145199,0.377670779,DB0120210001053_,0.973732417,-0.344390824,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levetiracetam,DB01202
,209378,DB00230,10021143,40,19634,26,8625,0.14020532,0.675838506,0.402139892,1.154255725,0.270140176,DB0023010021143_,1.308814283,-0.391801128,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,209385,DB00537,10062355,43,7514,28,4270,0.620763324,0.872719119,0.528973673,1.461070905,0.761234103,DB0053710062355_,0.272814343,-0.136141517,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,209397,DB00115,10069339,199,18226,161,10311,0.000912651,0.699292482,0.564390836,0.867409447,0.005112206,DB0011510069339_,5.276124243,-0.357686195,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,cyanocobalamin,DB00115
,209405,DB00169,10022972,61,38630,23,18152,0.413444104,1.246206686,0.759881254,2.110605548,0.582852585,DB0016910022972_,0.539820981,0.220104286,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,209425,DB01261,10064848,30,3751,40,3263,0.091359981,0.652471981,0.391460604,1.076892835,0.197450839,DB0126110064848_,1.622265641,-0.426987081,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,sitagliptin,DB01261
,209433,DB00557,10033557,51,5936,14,3053,0.035421858,1.873476239,1.019431216,3.671180992,0.096323561,DB0055710033557_,2.340042327,0.627795657,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,hydroxyzine,DB00557
,209434,DB00887,10033557,39,2302,11,1804,0.002248573,2.777788681,1.390389896,6.031607024,0.010700413,DB0088710033557_,4.537472946,1.021655173,female,10033557,Palpitations,10007541,Cardiac disorders,Card,bumetanide,DB00887
,209438,DB01137,10027175,46,7726,24,5569,0.225025867,1.381524399,0.824862829,2.369266936,0.379860312,DB0113710027175_,0.967951694,0.323187527,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,209477,DB00586,10006451,97,7012,19,2786,0.003521147,2.028295537,1.228697684,3.520802054,0.015396049,DB0058610006451_,4.173644353,0.707195804,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,diclofenac,DB00586
,209491,DB00635,10061599,44,33009,14,23780,0.007205647,2.26409484,1.217441383,4.474491217,0.027393756,DB0063510061599_,3.597440165,0.81717505,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,209494,DB00169,10064848,151,38540,82,18093,0.291522713,0.864505588,0.65598525,1.146148987,0.456970191,DB0016910064848_,0.783137117,-0.14559751,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,cholecalciferol,DB00169
,209495,DB00437,10064848,86,6835,86,11460,0.000846393,1.676541625,1.226877214,2.291205895,0.004796258,DB0043710064848_,5.339919307,0.516733115,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,allopurinol,DB00437
,209497,DB01050,10064848,124,17984,82,9289,0.089661245,0.781099438,0.585503335,1.046643946,0.194675849,DB0105010064848_,1.636419418,-0.247052816,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,ibuprofen,DB01050
,209498,DB01373,10064848,80,22640,34,7347,0.191073588,0.763570104,0.50474846,1.177670701,0.337922238,DB0137310064848_,1.084939476,-0.26975034,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,calcium,DB01373
,209516,DB00996,10013496,105,38848,52,22373,0.407047038,1.162922784,0.826032278,1.6548819,0.576591475,DB0099610013496_,0.55062128,0.150936478,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,209518,DB00476,10043417,59,17198,23,6154,0.70768928,0.917913161,0.557753924,1.558854621,0.82530781,DB0047610043417_,0.191998859,-0.085652488,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,209519,DB00996,10043417,102,38851,39,22386,0.028612139,1.506978326,1.032113112,2.240254258,0.08164469,DB0099610043417_,2.505378495,0.410106537,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,209520,DB01255,10043417,44,2089,11,1567,0.000511775,2.999644925,1.518413151,6.461677841,0.003147035,DB0125510043417_,5.761294458,1.098493923,female,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,lisdexamfetamine,DB01255
,209533,DB00030,10013573,54,2152,45,1776,1,0.990335811,0.650876239,1.513125566,1,DB0003010013573_,0,-0.009711191,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,insulin human,DB00030
,209534,DB00973,10047899,62,3789,26,2995,0.006624502,1.884727553,1.171197568,3.112804616,0.025638673,DB0097310047899_,3.663653407,0.633783276,NA,10047899,Weight increased,10022891,Investigations,Inv,ezetimibe,DB00973
,209537,DB00321,10049848,58,7389,26,2824,0.540301016,0.85260992,0.526986933,1.413987854,0.695894366,DB0032110049848_,0.362557403,-0.159453139,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,209538,DB00973,10049848,32,3819,20,3001,0.484159484,1.257250349,0.69573107,2.324589341,0.648382731,DB0097310049848_,0.433274123,0.228927074,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,ezetimibe,DB00973
,209544,DB01041,10028334,39,3006,28,3090,0.176295688,1.431688899,0.856259252,2.422590272,0.319064424,DB0104110028334_,1.142362242,0.358854796,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,thalidomide,DB01041
,209567,DB00787,10038428,81,16919,101,17147,0.180916361,0.812793969,0.598660916,1.100585654,0.325038734,DB0078710038428_,1.123810922,-0.207277622,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,acyclovir,DB00787
,209572,DB01041,10047700,44,3001,28,3090,0.057144661,1.617896174,0.982086856,2.706508316,0.138074865,DB0104110047700_,1.979959239,0.481126647,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,thalidomide,DB01041
,209594,DB01041,10044565,34,3011,22,3096,0.106714592,1.588953874,0.900407028,2.858919789,0.221213964,DB0104110044565_,1.508624885,0.463075859,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,thalidomide,DB01041
,209597,DB00331,10017413,95,24851,67,20685,0.305446502,1.180208341,0.853750726,1.63937577,0.472219356,DB0033110017413_,0.750311664,0.165690983,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,metformin,DB00331
,209622,DB00043,10020937,61,6352,18,2282,0.52289842,1.217447186,0.708163663,2.193935904,0.681292007,DB0004310020937_,0.383764273,0.196756196,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,omalizumab,DB00043
,209683,DB00126,10042682,57,10114,23,5922,0.162828313,1.451051712,0.878846023,2.470551378,0.301139294,DB0012610042682_,1.200182352,0.372288612,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,209691,DB13961,10042682,38,9419,14,6400,0.048281926,1.844225089,0.975818409,3.688019947,0.121852176,DB1396110042682_,2.104946641,0.612059183,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,209695,DB00787,10046735,144,16856,95,17153,0.001130362,1.542468659,1.181131101,2.022110683,0.006094679,DB0078710046735_,5.100339168,0.433384159,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,209700,DB01234,10005191,78,31547,53,32835,0.017936602,1.531764474,1.066507253,2.21490514,0.056717424,DB0123410005191_,2.869673809,0.426420322,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,209715,DB00635,10012431,45,33008,20,23774,0.078175155,1.620544958,0.937206893,2.897907602,0.175304692,DB0063510012431_,1.741229722,0.482762487,NA,10012431,Dermatitis,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,209753,DB00531,10013700,33,7219,20,6496,0.170484198,1.484702091,0.826138443,2.733299601,0.311488245,DB0053110013700_,1.166393678,0.39521414,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,cyclophosphamide,DB00531
,209766,DB00455,10024264,43,9358,38,5080,0.035115864,0.614274965,0.38719988,0.978036428,0.095644835,DB0045510024264_,2.347113581,-0.487312626,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,209785,DB06637,10027566,45,6117,8,2011,0.111929519,1.849038627,0.860776841,4.550098891,0.228982226,DB0663710027566_,1.474110895,0.614665843,NA,10027566,Micturition urgency,10038359,Renal and urinary disorders,Renal,dalfampridine,DB06637
,209787,DB00009,10020642,17,1334,38,1513,0.020170321,0.507511754,0.267293886,0.926280872,0.06218719,DB0000910020642_,2.777606244,-0.678235407,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,alteplase,DB00009
,209793,DB09038,10005557,71,2177,59,2482,0.090150988,1.371885401,0.952707902,1.981681761,0.195456653,DB0903810005557_,1.63241665,0.316185999,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,empagliflozin,DB09038
,209794,DB00399,10013700,61,6931,19,4979,0.000903271,2.306169804,1.357039715,4.093086551,0.005066683,DB0039910013700_,5.285068885,0.835588055,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,zoledronic acid,DB00399
,209828,DB00877,10025482,38,1070,34,1397,0.118285124,1.458966325,0.887583302,2.406710355,0.238669806,DB0087710025482_,1.432674246,0.377728189,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sirolimus,DB00877
,209830,DB08890,10035664,55,1892,18,541,0.668377273,0.87373763,0.500174367,1.59522918,0.798540788,DB0889010035664_,0.224969232,-0.134975143,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,linaclotide,DB08890
,209850,DB00349,10070863,37,985,18,926,0.027685563,1.931800008,1.063567021,3.63150747,0.079543317,DB0034910070863_,2.531453534,0.658452215,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,clobazam,DB00349
,209852,DB08931,10003988,219,6358,53,2393,0.003574495,1.555192119,1.142715811,2.149146931,0.015583943,DB0893110003988_,4.161514206,0.441599087,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,riociguat,DB08931
,209864,DB06637,10039906,143,6019,62,1957,0.070686186,0.749941216,0.550322013,1.032004963,0.162510836,DB0663710039906_,1.817010594,-0.287760454,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,209884,DB01248,10047942,34,2666,28,1346,0.058804621,0.613124674,0.359174253,1.054502859,0.141228878,DB0124810047942_,1.957373456,-0.489186981,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,docetaxel,DB01248
,209912,DB00455,10073318,71,9330,98,5020,1.72408846020209e-09,0.389836573,0.282528665,0.535643384,4.56371250517745e-08,DB0045510073318_,16.90254431,-0.942027672,NA,10073318,Accidental exposure to product by child,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,209917,DB06637,10019465,42,6120,13,2006,1,1.058948932,0.556277121,2.154735588,1,DB0663710019465_,0,0.057276843,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,209921,DB00203,10012601,34,13844,46,8892,0.001172174,0.474752336,0.295294572,0.756556558,0.006279544,DB0020310012601_,5.070457945,-0.744962008,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,sildenafil,DB00203
,209934,DB01097,10043414,45,6220,10,1493,1,1.080106941,0.535062656,2.409444965,1,DB0109710043414_,0,0.077060056,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,210092,DB00121,10021789,40,4183,10,458,0.028597402,0.438053315,0.213518273,0.989099097,0.081607068,DB0012110021789_,2.505839403,-0.825414653,NA,10021789,Infection,10021881,Infections and infestations,Infec,biotin,DB00121
,210130,DB01174,10007515,27,912,30,762,0.344135085,0.752103779,0.426093363,1.321757898,0.513471838,DB0117410007515_,0.666560094,-0.28488096,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,phenobarbital,DB01174
,210302,DB00787,10064355,34,16966,24,17224,0.189596365,1.438187457,0.827774957,2.536159227,0.336021877,DB0078710064355_,1.09057901,0.36338361,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,210306,DB09053,10064355,80,2205,127,3925,0.461833548,1.121263922,0.832608037,1.502639685,0.628981197,DB0905310064355_,0.463653916,0.114456551,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,ibrutinib,DB09053
,210384,DB04868,10006002,38,1603,16,1500,0.008450576,2.221746105,1.203752692,4.287105627,0.031118437,DB0486810006002_,3.469954814,0.798293421,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,nilotinib,DB04868
,210402,DB08911,10021097,34,1605,30,1718,0.451957082,1.213053802,0.716751558,2.062505769,0.619524492,DB0891110021097_,0.478803044,0.193140983,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,trametinib,DB08911
,210474,DB00115,10050584,206,18219,75,10397,0.000734893,1.56741138,1.19639169,2.072343302,0.004258522,DB0011510050584_,5.458833109,0.449425456,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,210574,DB01175,10013950,62,10662,37,4855,0.193550646,0.763015929,0.499072795,1.181256248,0.341109574,DB0117510013950_,1.075551523,-0.270476371,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,210577,DB00108,10039906,232,9962,86,3209,0.290455968,0.869015121,0.673385956,1.130040604,0.455676691,DB0010810039906_,0.785971732,-0.140394754,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,natalizumab,DB00108
,210579,DB00213,10039906,145,18750,105,13316,0.89755926,0.98072847,0.756851828,1.274377519,0.956338178,DB0021310039906_,0.044643686,-0.019459646,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,210611,DB01039,10005750,30,2943,30,3021,1,1.026504678,0.596211255,1.76739683,1,DB0103910005750_,0,0.026159515,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,fenofibrate,DB01039
,210629,DB00641,10017944,54,14070,36,12439,0.204943017,1.326103024,0.853323454,2.083122233,0.355022058,DB0064110017944_,1.035575355,0.282244584,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,210631,DB00722,10017944,92,25311,56,25976,0.002213822,1.685991649,1.195960633,2.395282713,0.010568529,DB0072210017944_,4.549874628,0.522353907,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,210721,DB00051,10042609,309,25422,131,11289,0.677896896,1.047445811,0.850063183,1.296561072,0.804780398,DB0005110042609_,0.217185837,0.046354639,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,adalimumab,DB00051
,210730,DB01024,10011831,41,2170,31,2089,0.342632793,1.273139096,0.775833164,2.108413612,0.511943097,DB0102410011831_,0.669541799,0.24148558,NA,10011831,Cytomegalovirus infection,10021881,Infections and infestations,Infec,mycophenolic acid,DB01024
,210742,DB14500,10054236,36,7773,21,4052,0.676769545,0.893655189,0.507039441,1.613358388,0.803963008,DB1450010054236_,0.218202021,-0.112435273,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,potassium,DB14500
,210826,DB01211,10019211,60,1592,30,757,0.81901851,0.951025323,0.598099917,1.540813197,0.903479192,DB0121110019211_,0.101502199,-0.050214589,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,clarithromycin,DB01211
,210865,DB00678,10015946,46,15553,13,10711,0.003250871,2.436767947,1.293699479,4.918905074,0.014436415,DB0067810015946_,4.23800145,0.890672549,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,losartan,DB00678
,210976,DB01306,10006451,41,4167,14,3852,0.000971456,2.706699039,1.442840193,5.384438873,0.005380264,DB0130610006451_,5.225017844,0.995729826,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,insulin aspart,DB01306
,211016,DB00051,10028997,55,25676,42,11378,0.010798069,0.580307313,0.381071816,0.889428383,0.037856683,DB0005110028997_,3.273947749,-0.544197466,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,adalimumab,DB00051
,211093,DB00005,10061819,45,128037,21,42398,0.200356726,0.709584611,0.413953093,1.254152425,0.349449357,DB0000510061819_,1.051396629,-0.343075535,NA,10061819,Disease recurrence,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,211144,DB00813,10013781,38,10534,22,10146,0.06941737,1.663603386,0.958400718,2.955317432,0.160269699,DB0081310013781_,1.830897261,0.508985964,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,fentanyl,DB00813
,211192,DB00555,10071408,51,6996,6,3480,0.000107728,4.227234048,1.811802935,12.06889821,0.000850136,DB0055510071408_,7.070114512,1.44154789,female,10071408,Maternal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,lamotrigine,DB00555
,211211,DB09072,10000496,40,6431,12,2523,0.536079855,1.307665299,0.671239413,2.742906345,0.692459531,DB0907210000496_,0.367505482,0.268243333,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,sodium oxybate,DB09072
,211309,DB09146,10037087,87,701,33,394,0.069980198,1.481323089,0.961307489,2.32831064,0.161254449,DB0914610037087_,1.824771734,0.392935668,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,iron sucrose,DB09146
,211325,DB00316,10039509,39,65435,24,36929,0.793210336,0.917089889,0.537740569,1.594484196,0.887894288,DB0031610039509_,0.118902588,-0.086549787,NA,10039509,Scab,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,211344,DB00213,10040882,40,18855,20,13401,0.237914682,1.421463532,0.811169811,2.567748595,0.39539627,DB0021310040882_,0.927866801,0.351686997,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,211429,DB00480,10003246,161,67267,83,67579,4.73955498467135e-07,1.948735116,1.485885172,2.571889084,7.39781489145406e-06,DB0048010003246_,11.81432589,0.667180504,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,211569,DB08932,10047924,181,19262,36,6561,0.002782822,1.712439232,1.190821935,2.524966444,0.012714491,DB0893210047924_,4.365012907,0.537918806,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,211623,DB00656,10033664,37,11976,13,6606,0.183830442,1.569911922,0.814875453,3.221064251,0.328740652,DB0065610033664_,1.112486131,0.451019517,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,211668,DB00218,10033775,35,1407,22,928,0.892012536,1.049283704,0.594210067,1.890511997,0.955072385,DB0021810033775_,0.045968145,0.048107745,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,moxifloxacin,DB00218
,211796,DB01276,10012735,68,1949,57,1454,0.521218668,0.890024037,0.612402064,1.297500214,0.680064167,DB0127610012735_,0.385568122,-0.116506808,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,exenatide,DB01276
,211860,DB00555,10040047,35,7012,22,3464,0.397997587,0.785967129,0.447531174,1.408718854,0.567719464,DB0055510040047_,0.566127883,-0.240840309,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,lamotrigine,DB00555
,211968,DB00682,10028997,40,19419,35,16329,0.907847345,0.960987541,0.59485578,1.558933323,0.958771936,DB0068210028997_,0.042102046,-0.039793834,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,warfarin,DB00682
,212018,DB01234,10042727,36,31589,19,32869,0.015221457,1.971478798,1.1010252,3.63939373,0.049884172,DB0123410042727_,2.998051516,0.67878392,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,dexamethasone,DB01234
,212026,DB00741,10016173,92,4002,51,3123,0.060671149,1.407641372,0.985713773,2.029599007,0.144661572,DB0074110016173_,1.933358249,0.341915518,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocortisone,DB00741
,212035,DB11093,10016173,73,1584,20,640,0.158740396,1.474547822,0.880293435,2.576052469,0.295805984,DB1109310016173_,1.218051499,0.388351381,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium citrate,DB11093
,212060,DB00158,10025197,40,16775,15,8089,0.47244954,1.285823362,0.694504138,2.507202366,0.638474867,DB0015810025197_,0.448672967,0.251399262,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,folic acid,DB00158
,212087,DB00158,10040844,60,16755,21,8083,0.235199749,1.378361608,0.82567094,2.387501768,0.392235853,DB0015810040844_,0.935891955,0.320895553,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,212142,DB00341,10035226,36,11369,26,5042,0.071938651,0.614078194,0.36019191,1.060383481,0.16467733,DB0034110035226_,1.803767297,-0.487633007,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cetirizine,DB00341
,212289,DB06643,10011878,46,52375,13,7502,0.045363206,0.506825707,0.269102665,1.023094468,0.116277913,DB0664310011878_,2.151772151,-0.679588107,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,denosumab,DB06643
,212333,DB00879,10013950,19,1758,31,3681,0.447727846,1.283226648,0.682903335,2.352087591,0.615524802,DB0087910013950_,0.485280039,0.249377725,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,emtricitabine,DB00879
,212385,DB00153,10033318,36,7387,17,3422,1,0.980993429,0.536074438,1.865238864,1,DB0015310033318_,0,-0.019189517,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,ergocalciferol,DB00153
,212391,DB00758,10033318,39,8261,38,10036,0.359520739,1.246814457,0.776061225,2.004703939,0.529219199,DB0075810033318_,0.636352567,0.220591864,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,clopidogrel,DB00758
,212456,DB00601,10053762,32,873,47,864,0.106896794,0.673981223,0.4118552,1.090481087,0.221473022,DB0060110053762_,1.507454493,-0.394553028,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,linezolid,DB00601
,212506,DB08889,10028596,15,3150,35,3850,0.044688713,0.523861362,0.26532549,0.986484637,0.114969446,DB0888910028596_,2.163088873,-0.646528206,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,carfilzomib,DB08889
,212588,DB00422,10064355,18,3417,39,2910,0.000768159,0.393111721,0.211170093,0.705536393,0.004421077,DB0042210064355_,5.42137195,-0.933661431,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,methylphenidate,DB00422
,212619,DB06228,10034474,66,15846,59,16017,0.530815132,1.130710777,0.783134565,1.635785316,0.687822319,DB0622810034474_,0.374224731,0.122846441,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,212681,DB11089,10016322,142,10033,92,8315,0.074181837,1.279162697,0.975464033,1.684269713,0.168506208,DB1108910016322_,1.78078269,0.246205721,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,212696,DB11089,10035742,48,10127,49,8358,0.307712454,0.808487891,0.530904671,1.230564921,0.474883857,DB1108910035742_,0.744685016,-0.212589577,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,212769,DB00047,10006784,48,9237,20,8498,0.002244332,2.207801413,1.284539964,3.930826631,0.010684101,DB0004710006784_,4.538998505,0.791997184,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,212774,DB00331,10006784,119,24827,65,20687,0.005982296,1.525463904,1.117562377,2.098306673,0.023610308,DB0033110006784_,3.74607188,0.422298563,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,metformin,DB00331
,212779,DB01101,10006784,61,7528,18,3890,0.04197186,1.75108863,1.019484959,3.153195286,0.109648694,DB0110110006784_,2.210473716,0.560237669,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,capecitabine,DB01101
,212879,DB00836,10028334,98,5437,35,4040,0.000130317,2.080393195,1.397754498,3.161158191,0.000999238,DB0083610028334_,6.908517593,0.732556912,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,loperamide,DB00836
,212883,DB01377,10028334,73,3723,35,2635,0.061401019,1.47610367,0.970357752,2.283715453,0.146036807,DB0137710028334_,1.923896585,0.389405961,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium oxide,DB01377
,212913,DB00836,10033775,46,5489,16,4059,0.009382784,2.125829829,1.17929578,4.028898348,0.033833113,DB0083610033775_,3.386315292,0.754162234,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,212962,DB01373,10040829,111,22609,23,7358,0.055176784,1.570562155,0.994779318,2.581618337,0.134646929,DB0137310040829_,2.00509927,0.451433616,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,calcium,DB01373
,212967,DB14513,10040829,42,7135,9,3555,0.016946549,2.325003513,1.113949018,5.438345916,0.054252057,DB1451310040829_,2.914114377,0.84372155,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,magnesium,DB14513
,212997,DB01593,10047895,35,1098,16,682,0.380773525,1.358501268,0.725800807,2.650017111,0.550802494,DB0159310047895_,0.596378984,0.306382083,NA,10047895,Weight decreased,10022891,Investigations,Inv,zinc,DB01593
,213020,DB01281,10022437,43,8889,10,1788,0.711440775,0.864972423,0.426998449,1.934065372,0.828037267,DB0128110022437_,0.188697118,-0.145057653,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,abatacept,DB01281
,213044,DB00281,10069889,339,11119,124,5547,0.003120642,1.363842599,1.104134177,1.693519437,0.013975683,DB0028110069889_,4.270436418,0.310306156,NA,10069889,Product adhesion issue,10077536,Product issues,Prod,lidocaine,DB00281
,213230,DB00381,10010071,67,29293,28,22859,0.005005223,1.867246561,1.184349824,3.016168097,0.020484592,DB0038110010071_,3.888082297,0.624464918,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,213311,DB00678,10048393,48,15551,10,10714,0.000231069,3.306847365,1.651130819,7.335497313,0.00162549,DB0067810048393_,6.421945898,1.195995278,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,losartan,DB00678
,213405,DB00331,10022000,219,24727,116,20636,6.9231156498839e-05,1.575559839,1.251353115,1.992333858,0.000581666,DB0033110022000_,7.44961478,0.454610662,NA,10022000,Influenza,10021881,Infections and infestations,Infec,metformin,DB00331
,213409,DB01039,10022000,39,2934,20,3031,0.012311074,2.014228274,1.143469309,3.654178731,0.042006437,DB0103910022000_,3.169932411,0.700236131,NA,10022000,Influenza,10021881,Infections and infestations,Infec,fenofibrate,DB01039
,213411,DB08889,10022000,33,3132,41,3844,1,0.987852645,0.603638551,1.605593912,1,DB0888910022000_,0,-0.012221737,NA,10022000,Influenza,10021881,Infections and infestations,Infec,carfilzomib,DB08889
,213413,DB00654,10069339,26,3790,41,2557,0.000659388,0.427894254,0.250615715,0.718506146,0.003900094,DB0065410069339_,5.546754516,-0.848879184,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,latanoprost,DB00654
,213430,DB00316,10056819,166,65308,75,36878,0.122278475,1.249856003,0.945666275,1.664901763,0.244709347,DB0031610056819_,1.407684113,0.223028347,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,213431,DB08820,10013710,37,4364,25,3520,0.523706646,1.193740271,0.69811377,2.07311543,0.681838089,DB0882010013710_,0.382963055,0.177091463,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ivacaftor,DB08820
,213449,DB00126,10039906,79,10092,49,5896,0.782758545,0.941918024,0.650300402,1.376216847,0.881806742,DB0012610039906_,0.12578236,-0.059837032,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,213455,DB00999,10039906,136,21294,92,12147,0.214011627,0.843274623,0.641866824,1.11204148,0.366242104,DB0099910039906_,1.004460677,-0.170462605,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,213475,DB00820,10062237,41,11874,30,5786,0.099503248,0.665955145,0.405333647,1.10577241,0.210099696,DB0082010062237_,1.560173117,-0.406532961,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,tadalafil,DB00820
,213477,DB01276,10022062,66,1951,58,1453,0.405835974,0.847513112,0.582417765,1.23607476,0.575403128,DB0127610022062_,0.552684392,-0.165448968,NA,10022062,Injection site extravasation,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,213481,DB01276,10022052,59,1958,21,1490,0.002743397,2.1375425,1.272997072,3.721313716,0.012568224,DB0127610022052_,4.376583595,0.759656805,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,213484,DB01276,10022061,91,1926,41,1470,0.00536168,1.693776114,1.151320966,2.528743251,0.021625251,DB0127610022061_,3.833893611,0.526960423,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,213490,DB01276,10022093,111,1906,42,1469,7.70768936779401e-05,2.036501121,1.405714932,2.998578449,0.000637497,DB0127610022093_,7.357960649,0.711233198,NA,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,213494,DB00321,10022061,46,7401,6,2844,0.007682392,2.946100221,1.253071747,8.449814125,0.028843262,DB0032110022061_,3.545878881,1.080482337,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,213573,DB00264,10028533,27,29580,37,24855,0.059276193,0.613178563,0.358945465,1.035002965,0.142134166,DB0026410028533_,1.950983835,-0.489099091,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metoprolol,DB00264
,213588,DB09053,10017412,26,2259,30,4022,0.123559406,1.543002842,0.874136779,2.706634205,0.24648116,DB0905310017412_,1.40046972,0.433730415,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,ibrutinib,DB09053
,213593,DB00046,10021789,51,5408,41,4651,0.833754898,1.069798575,0.69382234,1.658477988,0.913682907,DB0004610021789_,0.090271697,0.067470383,NA,10021789,Infection,10021881,Infections and infestations,Infec,insulin lispro,DB00046
,213647,DB00584,10048959,37,2044,28,1846,0.532141569,1.193369209,0.70762957,2.033249041,0.688980673,DB0058410048959_,0.372542059,0.176780575,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,enalapril,DB00584
,213736,DB08896,10013786,36,787,43,997,0.817641635,1.060549603,0.654869426,1.708942467,0.902539018,DB0889610013786_,0.102543356,0.058787267,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,regorafenib,DB08896
,213773,DB00559,10039906,69,9590,33,3273,0.111487197,0.713632876,0.463864271,1.117955726,0.228267999,DB0055910039906_,1.477234906,-0.337386628,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,bosentan,DB00559
,213988,DB00761,10060800,65,15242,24,8601,0.077352193,1.528276005,0.942976541,2.554757435,0.173852278,DB0076110060800_,1.749549315,0.424140306,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,potassium chloride,DB00761
,214009,DB00476,10013663,40,17217,21,6156,0.189062458,0.681066756,0.391762174,1.216848758,0.335346968,DB0047610013663_,1.092589558,-0.384094951,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,214067,DB00996,10014020,69,38884,10,22415,3.11397739970794e-06,3.977487536,2.037298055,8.664069759,3.91443787428614e-05,DB0099610014020_,10.14825373,1.380650348,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,gabapentin,DB00996
,214146,DB00121,10005750,50,4173,6,462,0.821653269,0.92258619,0.392416883,2.647699888,0.905009897,DB0012110005750_,0.099809399,-0.080574477,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,biotin,DB00121
,214150,DB00804,10005750,34,2966,17,882,0.093102883,0.594830826,0.321400094,1.141149749,0.200262625,DB0080410005750_,1.60812565,-0.519478241,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,dicyclomine,DB00804
,214156,DB00273,10076308,53,8428,13,2180,1,1.05456329,0.565854641,2.112676506,1,DB0027310076308_,0,0.053126738,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,topiramate,DB00273
,214157,DB00341,10076308,91,11314,22,5046,0.007784458,1.844741914,1.146397185,3.090930642,0.029130762,DB0034110076308_,3.535960535,0.612339384,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,214158,DB00404,10076308,129,19763,79,9783,0.13975561,0.808341333,0.60558158,1.084733649,0.269464604,DB0040410076308_,1.311318238,-0.212770868,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,214159,DB00722,10076308,145,25258,104,25928,0.005168396,1.431197131,1.10419356,1.860529775,0.021001979,DB0072210076308_,3.863138617,0.358511249,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,214162,DB01136,10076308,49,9835,37,11078,0.066612846,1.491658247,0.952721522,2.353590534,0.155243929,DB0113610076308_,1.862757662,0.399888418,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,214163,DB08893,10076308,37,2048,15,1043,0.554404513,1.256082832,0.669307029,2.475455821,0.707941935,DB0889310076308_,0.345393201,0.227998015,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,mirabegron,DB08893
,214164,DB13961,10076308,69,9388,28,6386,0.022065185,1.676226808,1.064657492,2.70497121,0.066783741,DB1396110076308_,2.706295623,0.51654532,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fish oil,DB13961
,214172,DB00285,10029354,45,10906,24,3694,0.094558174,0.635108182,0.37823225,1.091487969,0.202564108,DB0028510029354_,1.596698858,-0.453959929,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,venlafaxine,DB00285
,214199,DB00787,10033557,75,16925,29,17219,4.41303961796151e-06,2.631167854,1.692167825,4.192144534,5.29786464298325e-05,DB0078710033557_,9.845621623,0.967427799,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,acyclovir,DB00787
,214266,DB00112,10025415,52,5881,21,4070,0.041585755,1.71357986,1.012596142,3.000032318,0.108910633,DB0011210025415_,2.217227617,0.538584668,NA,10025415,Macular oedema,10015919,Eye disorders,Eye,bevacizumab,DB00112
,214271,DB01270,10025415,48,1210,20,949,0.018100616,1.881791507,1.087207242,3.371442798,0.057095246,DB0127010025415_,2.86303442,0.632224253,NA,10025415,Macular oedema,10015919,Eye disorders,Eye,ranibizumab,DB01270
,214298,DB01270,10047571,101,1157,71,898,0.575540738,1.104011908,0.796347442,1.537207941,0.724976676,DB0127010047571_,0.321615796,0.098950734,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,ranibizumab,DB01270
,214303,DB00331,10052140,41,24905,11,20741,0.000394643,3.10390589,1.566418803,6.698464773,0.002533918,DB0033110052140_,5.977988482,1.132661283,female,10052140,Eye pruritus,10015919,Eye disorders,Eye,metformin,DB00331
,214340,DB00191,10013709,56,1070,6,231,0.121936772,2.014078929,0.855270258,5.789587093,0.244173414,DB0019110013709_,1.409876594,0.700161984,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,phentermine,DB00191
,214397,DB00482,10021789,95,8164,27,3044,0.259580502,1.311849371,0.845935375,2.097429814,0.420723495,DB0048210021789_,0.865779442,0.271437875,NA,10021789,Infection,10021881,Infections and infestations,Infec,celecoxib,DB00482
,214455,DB00480,10040984,90,67338,108,67554,0.226702943,0.836008613,0.624716926,1.116460093,0.381808602,DB0048010040984_,0.962835837,-0.179116364,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,214457,DB00787,10040984,43,16957,32,17216,0.203835683,1.364256553,0.842910692,2.228851653,0.353616534,DB0078710040984_,1.039542189,0.310609631,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,acyclovir,DB00787
,214645,DB00264,10013082,60,29547,34,24858,0.077607181,1.484639604,0.958698999,2.333261898,0.174297423,DB0026410013082_,1.74699211,0.395172052,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,214647,DB00381,10013082,58,29302,39,22848,0.5391119,1.159599326,0.759324484,1.788100118,0.694941704,DB0038110013082_,0.363927316,0.148074537,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,214648,DB00451,10013082,124,47147,30,15389,0.159677814,1.3491167,0.8990137,2.084143039,0.297026385,DB0045110013082_,1.213934305,0.299450082,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,214737,DB01225,10069217,43,5001,24,4616,0.04987589,1.653645282,0.979482825,2.853760585,0.124784671,DB0122510069217_,2.081165657,0.502982113,NA,10069217,Needle issue,10077536,Product issues,Prod,enoxaparin,DB01225
,214802,DB01275,10028810,32,3947,24,3325,0.688754054,1.123177628,0.639701882,1.99704601,0.812391113,DB0127510028810_,0.207773389,0.116161836,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,hydralazine,DB01275
,214825,DB09038,10012735,82,2166,64,2477,0.028242678,1.465084453,1.038000498,2.07564639,0.080796561,DB0903810012735_,2.515820877,0.381912888,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,empagliflozin,DB09038
,214828,DB09038,10053762,40,2208,30,2511,0.091753494,1.516158026,0.917474346,2.53024665,0.198073308,DB0903810053762_,1.619118077,0.41617952,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,empagliflozin,DB09038
,214980,DB00028,10054112,82,13376,26,5589,0.24480976,1.317742673,0.837692374,2.137320113,0.403568207,DB0002810054112_,0.907409766,0.275920176,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,human immunoglobulin g,DB00028
,214987,DB08931,10003445,89,6488,48,2398,0.041582352,0.685341185,0.47557941,0.998146032,0.108910633,DB0893110003445_,2.217227617,-0.377838485,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,215001,DB08931,10017944,105,6472,53,2393,0.070985967,0.732543887,0.519765318,1.043038043,0.163013011,DB0893110017944_,1.81392526,-0.311232026,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,215114,DB00598,10003549,37,1551,24,1004,1,0.997959001,0.577315959,1.755011622,1,DB0059810003549_,0,-0.002043085,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,labetalol,DB00598
,215157,DB06724,10028810,136,7793,43,3876,0.010206005,1.57301993,1.106264995,2.276376476,0.036146983,DB0672410028810_,3.320161784,0.452997294,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,215310,DB00421,10064687,63,8840,17,5235,0.003433442,2.194492363,1.266662415,4.005457282,0.015092906,DB0042110064687_,4.193530479,0.78595075,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,spironolactone,DB00421
,215316,DB00264,10037153,281,29326,162,24730,0.000102475,1.462711278,1.200323849,1.787247194,0.000814997,DB0026410037153_,7.112326263,0.380291753,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,215322,DB00126,10040844,44,10127,19,5926,0.297012541,1.355102164,0.774027478,2.460041932,0.462879313,DB0012610040844_,0.770288921,0.303876849,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,ascorbic acid,DB00126
,215410,DB00051,10017553,50,25681,22,11398,1,1.008706662,0.599334563,1.750020777,1,DB0005110017553_,0,0.008668978,NA,10017553,Furuncle,10021881,Infections and infestations,Infec,adalimumab,DB00051
,215461,DB01224,10076308,43,8065,15,5902,0.011274031,2.097719807,1.14121291,4.069532367,0.039161875,DB0122410076308_,3.240051583,0.740850948,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,215464,DB00480,10074170,68,67360,41,67621,0.009579743,1.664946392,1.113612155,2.516779182,0.034411145,DB0048010074170_,3.369374771,0.509792926,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,215518,DB08895,10024910,48,28066,12,6634,0.869426326,0.945479327,0.494401637,1.956614641,0.941900916,DB0889510024910_,0.059855195,-0.056063256,NA,10024910,Low density lipoprotein increased,10022891,Investigations,Inv,tofacitinib,DB08895
,215540,DB00331,10029223,45,24901,34,20718,0.734840813,1.101157961,0.689529265,1.773447188,0.846679121,DB0033110029223_,0.166433498,0.096362318,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,metformin,DB00331
,215606,DB00557,10043071,64,5923,47,3020,0.068811736,0.694305839,0.467788125,1.037161846,0.159182968,DB0055710043071_,1.837700994,-0.364842726,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,hydroxyzine,DB00557
,215626,DB01362,10010836,45,821,29,561,0.903390255,1.060281096,0.641623562,1.776586089,0.957387878,DB0136210010836_,0.043546663,0.058534058,NA,10010836,Contrast media reaction,10021428,Immune system disorders,Immun,iohexol,DB01362
,215636,DB00540,10013654,47,2436,33,1058,0.048563437,0.618664652,0.385570482,1.002938835,0.122362332,DB0054010013654_,2.100768701,-0.480191911,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,nortriptyline,DB00540
,215832,DB01238,10027951,32,5218,19,3483,0.774978657,1.124219782,0.616991666,2.102784273,0.877323349,DB0123810027951_,0.130879655,0.117089268,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,215870,DB05679,10000087,46,6885,16,4893,0.013525731,2.043066299,1.133734497,3.871061743,0.045283893,DB0567910000087_,3.094803863,0.714451767,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ustekinumab,DB05679
,215873,DB05679,10012735,174,6757,100,4809,0.094165385,1.238346605,0.959990309,1.60455298,0.202010784,DB0567910012735_,1.599434195,0.213777107,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ustekinumab,DB05679
,215875,DB05679,10028813,201,6730,77,4832,1.81954490652017e-06,1.874101945,1.430309009,2.476629793,2.43765228684417e-05,DB0567910028813_,10.62189007,0.628129582,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ustekinumab,DB05679
,216037,DB00230,10067482,106,19568,45,8606,0.92943379,1.035941939,0.723714094,1.504272715,0.970939263,DB0023010067482_,0.029491364,0.035311099,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,216040,DB00230,10074902,117,19557,21,8630,3.9779083235867e-05,2.458462361,1.534812495,4.123314579,0.000362801,DB0023010074902_,7.921655394,0.899536098,NA,10074902,Expired product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,216159,DB00257,10035664,52,900,37,585,0.737948558,0.913567568,0.579757486,1.451953845,0.849050265,DB0025710035664_,0.163636889,-0.09039794,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,clotrimazole,DB00257
,216199,DB00722,10000084,33,25370,18,26014,0.0348127,1.879836134,1.027870414,3.546574941,0.09505807,DB0072210000084_,2.353267315,0.63118461,NA,10000084,Abdominal pain lower,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,216249,DB00472,10061822,46,10713,17,4295,0.889083591,1.08482148,0.609370812,2.020784358,0.953955749,DB0047210061822_,0.047137994,0.081415439,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,216251,DB00727,10061822,35,3808,27,4146,0.202251757,1.411286693,0.828181173,2.429298961,0.351657843,DB0072710061822_,1.045096612,0.344501837,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,216259,DB00999,10020919,34,21396,21,12218,0.780331814,0.924546407,0.521097652,1.677124167,0.88041472,DB0099910020919_,0.127362209,-0.078452033,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,216319,DB00601,10069339,20,885,40,871,0.012035,0.492279445,0.270333496,0.870228578,0.041238426,DB0060110069339_,3.188384782,-0.708708745,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,linezolid,DB00601
,216322,DB00760,10069339,43,737,57,958,1,0.98060846,0.636427951,1.501565252,1,DB0076010069339_,0,-0.019582023,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,meropenem,DB00760
,216323,DB01327,10069339,21,642,30,727,0.475992791,0.792808682,0.426804119,1.447818837,0.641432955,DB0132710069339_,0.444050613,-0.232173345,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,cefazolin,DB01327
,216324,DB01413,10069339,94,1126,159,1500,0.083358677,0.787624979,0.596556422,1.035441508,0.184062737,DB0141310069339_,1.692478617,-0.238733217,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,cefepime,DB01413
,216442,DB00904,10023644,34,23035,22,14434,0.891691184,0.968380263,0.549980545,1.738723497,0.955005127,DB0090410023644_,0.04603857,-0.032130435,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,ondansetron,DB00904
,216520,DB00451,10051076,74,47197,26,15393,0.728152923,0.928248418,0.586375295,1.512950691,0.841426135,DB0045110051076_,0.172657047,-0.07445589,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,216842,DB01062,10046735,45,4441,9,1736,0.067790218,1.954336542,0.940814812,4.557225732,0.157359994,DB0106210046735_,1.849219144,0.670050771,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,oxybutynin,DB01062
,216908,DB08931,10015150,78,6499,18,2428,0.065288581,1.618899555,0.957994776,2.878956661,0.152930565,DB0893110015150_,1.877771282,0.481746631,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,riociguat,DB08931
,216931,DB08931,10042674,209,6368,77,2369,1,1.00975969,0.770463477,1.334757514,1,DB0893110042674_,0,0.009712372,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,216940,DB00222,10001760,42,3164,9,3119,3.37160277693208e-06,4.599137708,2.202039658,10.76560949,4.18618706189331e-05,DB0022210001760_,10.08113515,1.525868831,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,glimepiride,DB00222
,216959,DB00186,10003119,33,16868,22,9986,0.676859039,0.888019733,0.502118716,1.599691435,0.804020128,DB0018610003119_,0.218130976,-0.118761314,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,lorazepam,DB00186
,216980,DB00222,10010774,70,3136,56,3072,0.28073704,1.224448741,0.846124121,1.778962661,0.444628718,DB0022210010774_,0.810515688,0.202490735,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,glimepiride,DB00222
,217100,DB06605,10012378,77,13996,43,12990,0.007744843,1.661948821,1.128965772,2.47508293,0.029027414,DB0660510012378_,3.539514579,0.507990902,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,apixaban,DB06605
,217129,DB08895,10062352,90,28024,17,6629,0.460541324,1.252299255,0.739666529,2.245528796,0.627918599,DB0889510062352_,0.46534474,0.224981266,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,217144,DB01132,10030124,22,1263,32,1498,0.493175957,0.815478803,0.448965887,1.456108796,0.655962455,DB0113210030124_,0.421651725,-0.203979849,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,pioglitazone,DB01132
,217186,DB08868,10008190,48,9154,8,2503,0.252060401,1.640507014,0.767970266,4.020782453,0.412167611,DB0886810008190_,0.886325189,0.495005349,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,217238,DB04868,10025482,39,1602,27,1489,0.263865651,1.342430444,0.796605924,2.29259914,0.425725602,DB0486810025482_,0.853960268,0.294481735,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,nilotinib,DB04868
,217255,DB00557,10024855,48,5939,14,3053,0.060382891,1.762390459,0.953880466,3.466956162,0.144143519,DB0055710024855_,1.936945816,0.566671103,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,217367,DB00512,10038905,78,4659,29,5069,2.48910469256601e-07,2.926050703,1.884350583,4.658645405,4.1369659718051e-06,DB0051210038905_,12.3955479,1.073653631,female,10038905,Retinal vasculitis,10015919,Eye disorders,Eye,vancomycin,DB00512
,217457,DB00281,10017955,48,11410,36,5635,0.062927818,0.658487957,0.418067013,1.045637338,0.148813108,DB0028110017955_,1.905064069,-0.417809047,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,lidocaine,DB00281
,217471,DB01067,10017955,43,4318,54,4769,0.541731304,0.87947927,0.573847578,1.340624893,0.697104611,DB0106710017955_,0.360819793,-0.128425285,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,glipizide,DB01067
,217513,DB06605,10040047,170,13903,159,12874,0.955750629,0.990048643,0.791721364,1.23858011,0.993412234,DB0660510040047_,0.006609561,-0.010001202,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,apixaban,DB06605
,217553,DB01275,10043607,30,3949,20,3329,0.477323426,1.264456002,0.693250241,2.353960984,0.642719847,DB0127510043607_,0.442046346,0.234641992,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,hydralazine,DB01275
,217554,DB06605,10043607,319,13754,270,12763,0.278539803,1.096325826,0.927648372,1.296500473,0.442341705,DB0660510043607_,0.815672608,0.091964431,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,apixaban,DB06605
,217592,DB01067,10048294,30,4331,22,4801,0.163706073,1.511537655,0.841780768,2.754591136,0.302379687,DB0106710048294_,1.196071811,0.413127447,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,glipizide,DB01067
,217599,DB00343,10069339,128,8608,129,4966,1.10719778532847e-05,0.572485227,0.443576968,0.738743114,0.000118496,DB0034310069339_,9.040628735,-0.557768348,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,diltiazem,DB00343
,217606,DB00814,10069339,93,8194,52,3363,0.08071687,0.734039265,0.515986359,1.054096579,0.179541587,DB0081410069339_,1.717348415,-0.309192757,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,meloxicam,DB00814
,217612,DB01162,10069339,14,259,51,1651,0.096690472,1.749270337,0.881064217,3.265088267,0.205792684,DB0116210069339_,1.580886006,0.559198751,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,terazosin,DB01162
,217613,DB01275,10069339,172,3807,203,3146,0.000794335,0.700219793,0.564942624,0.867100975,0.004548434,DB0127510069339_,5.392972207,-0.356361004,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,hydralazine,DB01275
,217746,DB01590,10015150,38,4700,15,2852,0.20001575,1.537165908,0.824292106,3.013754983,0.349016762,DB0159010015150_,1.05263533,0.429940402,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,everolimus,DB01590
,217930,DB00682,10049771,16,19443,42,16322,5.24294878684661e-05,0.31981134,0.167790242,0.581146749,0.00046006,DB0068210049771_,7.684154108,-1.140024021,male,10049771,Shock haemorrhagic,10047065,Vascular disorders,Vasc,warfarin,DB00682
,217951,DB08893,10010774,56,2029,32,1026,0.569742801,0.884958668,0.559238754,1.42180438,0.720564479,DB0889310010774_,0.327720376,-0.122214338,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,mirabegron,DB08893
,218039,DB13961,10016807,66,9391,33,6381,0.181393314,1.358934515,0.88069474,2.133778394,0.325622212,DB1396110016807_,1.122017427,0.306700948,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,fish oil,DB13961
,218129,DB00421,10005364,51,8852,32,5220,0.8199865,0.939834689,0.591637073,1.513289693,0.904178088,DB0042110005364_,0.100728938,-0.062051282,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,spironolactone,DB00421
,218170,DB00996,10017626,41,38912,25,22400,0.799771261,0.944080325,0.560381907,1.620433476,0.891761512,DB0099610017626_,0.114556546,-0.057544026,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,gabapentin,DB00996
,218203,DB00333,10069339,25,3046,49,3103,0.007099392,0.519807259,0.30681646,0.860612655,0.027087753,DB0033310069339_,3.608673575,-0.654297193,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,methadone,DB00333
,218207,DB01132,10069339,18,1267,37,1493,0.056043247,0.573373294,0.305690178,1.038879248,0.136170896,DB0113210069339_,1.993844593,-0.556218302,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,pioglitazone,DB01132
,218312,DB00656,10042682,50,11963,9,6610,0.000900362,3.069495157,1.493195123,7.104549556,0.005053061,DB0065610042682_,5.287761007,1.121513104,female,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,218343,DB06605,10005734,68,14005,61,12972,0.860400514,1.032535639,0.71935715,1.484879508,0.934268331,DB0660510005734_,0.06799159,0.032017563,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,apixaban,DB06605
,218367,DB01109,10019303,32,4380,29,4241,0.8978863,1.068450828,0.62480768,1.833968477,0.956338178,DB0110910019303_,0.044643686,0.066209775,NA,10019303,Heart rate increased,10022891,Investigations,Inv,heparin,DB01109
,218380,DB00682,10064848,86,19373,52,16312,0.060017584,1.392517543,0.974983566,2.005809765,0.143486489,DB0068210064848_,1.941514404,0.331113291,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,warfarin,DB00682
,218381,DB00820,10064848,35,11880,22,5794,0.396466603,0.775940726,0.442142564,1.389772539,0.566027084,DB0082010064848_,0.56911335,-0.253679146,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,tadalafil,DB00820
,218665,DB00814,10008531,77,8210,13,3402,0.001521107,2.454200686,1.351582299,4.823125592,0.007782863,DB0081410008531_,4.855831039,0.897801122,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,218684,DB01036,10013573,51,1450,12,410,0.644842173,1.201611118,0.624647913,2.500161873,0.780709787,DB0103610013573_,0.24755179,0.183663255,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,tolterodine,DB01036
,218699,DB00814,10013950,48,8239,8,3407,0.012031678,2.480939775,1.161788735,6.079123572,0.041232418,DB0081410013950_,3.188530485,0.90863743,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,218781,DB01015,10034474,19,9868,34,9347,0.027326813,0.529340481,0.285024145,0.955483571,0.078707569,DB0101510034474_,2.54201595,-0.636123423,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,sulfamethoxazole,DB01015
,218844,DB06643,10043554,60,52361,21,7494,0.001054324,0.408931199,0.245010723,0.708240617,0.00575793,DB0664310043554_,5.15717729,-0.894208356,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,denosumab,DB06643
,218866,DB14500,10047513,58,7751,27,4046,0.730952641,1.121309871,0.69753896,1.844833671,0.843508064,DB1450010047513_,0.170185816,0.11449753,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,potassium,DB14500
,218937,DB00341,10013538,38,11367,13,5055,0.45173311,1.299858504,0.676628575,2.661834669,0.619362829,DB0034110013538_,0.479064024,0.262255415,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,cetirizine,DB00341
,218968,DB01229,10073755,51,5690,6,2703,0.000277329,4.036924245,1.729626508,11.52745757,0.001893157,DB0122910073755_,6.269509218,1.395483076,female,10073755,Pneumocystis jirovecii pneumonia,10021881,Infections and infestations,Infec,paclitaxel,DB01229
,219005,DB01225,10017788,8,5036,44,4596,6.38886376254449e-08,0.165965093,0.067419666,0.356904427,1.20770430779203e-06,DB0122510017788_,13.62678927,-1.795977794,male,10017788,Gastric haemorrhage,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,219046,DB01104,10037884,56,15407,14,7272,0.029478979,1.887926438,1.036392149,3.67505068,0.083569345,DB0110410037884_,2.482078507,0.635479104,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,sertraline,DB01104
,219069,DB00814,10003285,68,8219,27,3388,0.910332372,1.038139373,0.654476575,1.690189198,0.959579421,DB0081410003285_,0.041260194,0.037430047,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,219081,DB08893,10003988,41,2044,11,1047,0.055364547,1.908876739,0.958672929,4.135561252,0.134952207,DB0889310003988_,2.002834583,0.646514974,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,mirabegron,DB08893
,219088,DB08893,10012735,85,2000,33,1025,0.197496235,1.31997563,0.866587916,2.052460444,0.345995506,DB0889310012735_,1.061329493,0.277613275,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,mirabegron,DB08893
,219097,DB00404,10016766,71,19821,26,9836,0.196249047,1.355133726,0.85313578,2.214712534,0.344525377,DB0040410016766_,1.065587528,0.30390014,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,219196,DB06643,10042128,145,52276,14,7501,0.186129145,1.486120501,0.857089288,2.78775327,0.331607925,DB0664310042128_,1.103801958,0.396169034,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,denosumab,DB06643
,219201,DB00007,10064355,23,1924,54,4398,1,0.973592371,0.568518614,1.618912152,1,DB0000710064355_,0,-0.026762574,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,leuprolide,DB00007
,219294,DB06273,10008479,58,5037,20,1390,0.406681609,0.800307159,0.472318789,1.409868966,0.576242002,DB0627310008479_,0.551227564,-0.222759676,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,219304,DB06273,10011224,79,5016,19,1391,0.710756253,1.153010973,0.689108396,2.022683329,0.82752605,DB0627310011224_,0.189314691,0.142376758,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tocilizumab,DB06273
,219346,DB00635,10019304,42,33011,11,23783,0.001891866,2.750741636,1.391523315,5.925619898,0.009293223,DB0063510019304_,4.678469874,1.011870561,female,10019304,Heart rate irregular,10022891,Investigations,Inv,prednisone,DB00635
,219364,DB01097,10022437,53,6212,17,1486,0.288534834,0.745817263,0.423600102,1.378200789,0.453583213,DB0109710022437_,0.790576536,-0.293274664,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,leflunomide,DB01097
,219374,DB00924,10023232,98,10064,23,4228,0.011932408,1.789976012,1.125688644,2.958992566,0.040972352,DB0092410023232_,3.194857775,0.582202219,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,219388,DB00959,10028836,47,8031,11,4991,0.002559463,2.655170105,1.355711888,5.682184939,0.011879832,DB0095910028836_,4.432913139,0.976508722,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,methylprednisolone,DB00959
,219390,DB01097,10028836,51,6214,8,1495,0.32136371,1.533648408,0.72044382,3.750140524,0.489683774,DB0109710028836_,0.713995455,0.427649477,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,219409,DB06273,10033775,45,5050,11,1399,0.870605712,1.133281413,0.575192922,2.436249567,0.942634694,DB0627310033775_,0.059076458,0.12511733,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,tocilizumab,DB06273
,219415,DB00924,10039073,131,10031,13,4238,3.30795978065e-09,4.257417217,2.401269541,8.218115345,8.26911296570472e-08,DB0092410039073_,16.3081535,1.448662689,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,219416,DB00959,10039073,72,8006,19,4983,0.00047918,2.358456905,1.404874679,4.147485058,0.002982183,DB0095910039073_,5.815099857,0.858007551,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,methylprednisolone,DB00959
,219452,DB00999,10048908,60,21370,23,12216,0.110165107,1.491224273,0.907797114,2.528912833,0.226305329,DB0099910048908_,1.485870178,0.399597442,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,hydrochlorothiazide,DB00999
,219462,DB00814,10050584,95,8192,20,3395,0.005110331,1.968439091,1.203673447,3.372716644,0.020820746,DB0081410050584_,3.8718054,0.677240889,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,meloxicam,DB00814
,219468,DB00073,10052904,47,7359,12,6395,3.77903383726705e-05,3.403193073,1.775732703,7.054632782,0.000347679,DB0007310052904_,7.964230776,1.22471413,female,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,rituximab,DB00073
,219478,DB01097,10052904,94,6171,24,1479,0.814175239,0.938704031,0.591936732,1.542927468,0.900338508,DB0109710052904_,0.104984467,-0.063255045,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,219529,DB00065,10054112,38,9426,32,4925,0.057575649,0.620458522,0.376966221,1.027327195,0.138880054,DB0006510054112_,1.97414464,-0.477296522,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,infliximab,DB00065
,219586,DB00395,10007515,54,2130,37,699,0.001252017,0.479076695,0.306593402,0.755683369,0.006620914,DB0039510007515_,5.017521782,-0.735894579,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,carisoprodol,DB00395
,219589,DB00814,10007515,41,8246,33,3382,0.004626965,0.509576472,0.313786224,0.833383205,0.019213187,DB0081410007515_,3.952158435,-0.674175345,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,meloxicam,DB00814
,219590,DB00829,10007515,139,7913,94,4360,0.129236823,0.814790841,0.620931677,1.073042654,0.254513366,DB0082910007515_,1.368401925,-0.204823836,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,diazepam,DB00829
,219595,DB00178,10017955,20,1417,47,1633,0.008796766,0.490516299,0.273924536,0.848763739,0.03212546,DB0017810017955_,3.438106406,-0.712296771,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ramipril,DB00178
,219623,DB06643,10049438,38,52383,13,7502,0.009860735,0.418628648,0.218032665,0.856887263,0.03516729,DB0664310049438_,3.347638897,-0.870771034,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,219675,DB00421,10014625,30,8873,29,5223,0.059221961,0.608987451,0.352729911,1.052763366,0.142023562,DB0042110014625_,1.951762303,-0.495957617,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,spironolactone,DB00421
,219723,DB01233,10042772,33,3388,17,1709,1,0.979173196,0.528236109,1.879984932,1,DB0123310042772_,0,-0.021046741,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,metoclopramide,DB01233
,219806,DB13867,10047513,35,4515,15,2539,0.460131524,1.312100663,0.696665208,2.591181168,0.627566776,DB1386710047513_,0.465905198,0.271629412,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,fluticasone,DB13867
,219836,DB06228,10006093,33,15879,51,16025,0.062917318,0.653020271,0.407977867,1.032234254,0.148801664,DB0622810006093_,1.905140975,-0.426147107,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,219880,DB00741,10029331,38,4056,29,3145,1,1.016032925,0.608737857,1.712321456,1,DB0074110029331_,0,0.015905756,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,hydrocortisone,DB00741
,220132,DB00186,10051792,47,16854,27,9981,1,1.0308734,0.628549669,1.722543802,1,DB0018610051792_,0,0.030406404,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,220169,DB06228,10054236,43,15869,23,16053,0.013435314,1.891194143,1.114051789,3.289211085,0.045040313,DB0622810054236_,3.100197352,0.637208451,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,220242,DB00480,10047943,80,67348,67,67595,0.284225758,1.198405729,0.855214507,1.683820094,0.448715681,DB0048010047943_,0.80136582,0.180992115,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,lenalidomide,DB00480
,220373,DB00121,10011906,68,4155,23,445,1.80696460247685e-05,0.316737461,0.192636703,0.538209744,0.000182537,DB0012110011906_,8.608558988,-1.149682049,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,220435,DB00476,10046306,130,17127,30,6147,0.030328323,1.55517099,1.037811084,2.399682138,0.085392317,DB0047610046306_,2.460499148,0.441585501,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,duloxetine,DB00476
,220471,DB00482,10008531,40,8219,25,3046,0.049063895,0.592997979,0.350358177,1.021765966,0.123216404,DB0048210008531_,2.093813091,-0.522564288,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,220542,DB00537,10047899,67,7490,32,4266,0.46298503,1.192466328,0.770096878,1.881515988,0.630155422,DB0053710047899_,0.461788788,0.176023707,NA,10047899,Weight increased,10022891,Investigations,Inv,ciprofloxacin,DB00537
,220603,DB01590,10039906,57,4681,63,2804,0.001152076,0.542036506,0.370830369,0.790756965,0.006194603,DB0159010039906_,5.084076882,-0.612421926,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,everolimus,DB01590
,220653,DB00924,10017955,47,10115,31,4220,0.060819427,0.632554208,0.392920468,1.03148633,0.144928938,DB0092410017955_,1.931511742,-0.457989358,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,220657,DB09153,10017955,40,7759,45,5654,0.047650636,0.647769504,0.411689041,1.015921683,0.120672651,DB0915310017955_,2.114673763,-0.434220349,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,220685,DB00480,10005554,27,67401,41,67621,0.114200182,0.660691571,0.390783985,1.100312236,0.232414678,DB0048010005554_,1.459232098,-0.414468157,NA,10005554,Blood glucose abnormal,10022891,Investigations,Inv,lenalidomide,DB00480
,220720,DB00437,10016807,116,6805,101,11445,1.8723799500837e-06,1.931609612,1.463894654,2.552111348,2.49888332002792e-05,DB0043710016807_,10.5970815,0.658353651,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,allopurinol,DB00437
,220728,DB00331,10018852,34,24912,27,20725,0.898153202,1.047622161,0.613314807,1.805976652,0.956353692,DB0033110018852_,0.044627464,0.046522987,NA,10018852,Haematoma,10047065,Vascular disorders,Vasc,metformin,DB00331
,220766,DB00264,10028164,35,29572,18,24874,0.098047972,1.635518686,0.901269839,3.068334289,0.207938594,DB0026410028164_,1.570512464,0.491959993,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,metoprolol,DB00264
,220773,DB00695,10028164,53,27996,13,20515,0.000146796,2.987389842,1.606026936,5.975400337,0.001105914,DB0069510028164_,6.807083268,1.094400044,female,10028164,Multiple allergies,10021428,Immune system disorders,Immun,furosemide,DB00695
,220774,DB00761,10028164,40,15267,10,8615,0.017954742,2.257086449,1.108498195,5.064372896,0.056748937,DB0076110028164_,2.869118346,0.8140748,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,potassium chloride,DB00761
,220817,DB00203,10069339,149,13729,138,8800,0.002292766,0.6921014,0.544428874,0.880265895,0.010874295,DB0020310069339_,4.521353526,-0.368022802,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,sildenafil,DB00203
,220818,DB00374,10069339,149,17567,86,5638,3.29125016021129e-05,0.556076738,0.422842855,0.735104543,0.000307757,DB0037410069339_,8.086199842,-0.586848977,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,treprostinil,DB00374
,220824,DB06228,10069339,211,15701,360,15716,5.86909630282272e-10,0.586684521,0.491879014,0.69833536,1.69899995946801e-08,DB0622810069339_,17.89064093,-0.533268046,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,rivaroxaban,DB06228
,220833,DB00073,10054889,31,7375,38,6369,0.148833225,0.704534013,0.42334459,1.164305524,0.282369001,DB0007310054889_,1.264540548,-0.350218669,NA,10054889,Transaminases increased,10022891,Investigations,Inv,rituximab,DB00073
,220834,DB00207,10054889,17,9063,37,5418,6.31533948837325e-06,0.274696973,0.144882114,0.500753876,7.26471328017028e-05,DB0020710054889_,9.529896635,-1.292086705,male,10054889,Transaminases increased,10022891,Investigations,Inv,azithromycin,DB00207
,220839,DB00028,10069339,41,13417,41,5574,0.000128279,0.415461751,0.262516171,0.657575253,0.000986053,DB0002810069339_,6.921800597,-0.878364725,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,human immunoglobulin g,DB00028
,220840,DB00073,10069339,70,7336,161,6246,7.02363618005832e-13,0.370206366,0.274960473,0.494165857,3.21071786074492e-11,DB0007310069339_,24.16194148,-0.993694682,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,rituximab,DB00073
,220841,DB00207,10069339,150,8930,168,5287,2.15699181175218e-08,0.528624724,0.420152847,0.664613923,4.49259348430318e-07,DB0020710069339_,14.6156655,-0.637476505,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,azithromycin,DB00207
,220856,DB08932,10019196,118,19325,38,6559,0.853607844,1.053917345,0.724766703,1.563710143,0.928648739,DB0893210019196_,0.074024719,0.052514027,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,220908,DB00275,10016173,56,2004,23,1214,0.127228294,1.474797995,0.887584019,2.525184527,0.251757622,DB0027510016173_,1.379288473,0.388521028,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,olmesartan,DB00275
,220987,DB00451,10049088,66,47205,12,15407,0.064949045,1.795023824,0.961704428,3.649947142,0.152366071,DB0045110049088_,1.88146929,0.585018294,NA,10049088,Osteopenia,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,221024,DB05259,10028810,83,11187,13,2715,0.155655853,1.54944237,0.856670268,3.036223912,0.291642775,DB0525910028810_,1.232225599,0.437895105,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,glatiramer,DB05259
,221031,DB00285,10051118,48,10903,19,3699,0.574164318,0.857121704,0.493739872,1.546179029,0.723954098,DB0028510051118_,0.323027289,-0.154175359,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,221071,DB00313,10039897,32,1207,26,1491,0.141687624,1.520108527,0.872348851,2.671465515,0.272108997,DB0031310039897_,1.301552567,0.418781731,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,valproic acid,DB00313
,221119,DB00586,10042458,42,7067,17,2788,0.885850356,0.974672692,0.542006593,1.829483534,0.952535694,DB0058610042458_,0.048627699,-0.025653565,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,diclofenac,DB00586
,221121,DB00863,10042458,56,10617,14,5826,0.007998301,2.19487766,1.204589846,4.273492936,0.029774378,DB0086310042458_,3.514107064,0.786126309,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,ranitidine,DB00863
,221225,DB00437,10066152,34,6887,25,11521,0.001796441,2.275011033,1.316652614,3.981285398,0.00890513,DB0043710066152_,4.721127756,0.821984902,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,allopurinol,DB00437
,221254,DB00758,10036790,36,8264,31,10043,0.176503363,1.411242074,0.847858977,2.361498672,0.319352325,DB0075810036790_,1.141460318,0.34447022,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,221259,DB00758,10039906,58,8242,64,10010,0.648352106,1.100644172,0.757007043,1.597401929,0.783321157,DB0075810039906_,0.244212504,0.095895619,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,221263,DB00559,10049848,46,9613,9,3297,0.161388116,1.75281586,0.846556886,4.077826564,0.29931816,DB0055910049848_,1.206248191,0.561223558,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,bosentan,DB00559
,221334,DB00715,10027175,81,4762,31,2256,0.358744254,1.23779841,0.80624262,1.944146365,0.528475744,DB0071510027175_,0.63775837,0.213334326,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,paroxetine,DB00715
,221335,DB00737,10027175,56,2745,9,923,0.041865817,2.091963866,1.021686911,4.830151874,0.109453648,DB0073710027175_,2.212254121,0.738103274,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,meclizine,DB00737
,221359,DB00268,10030124,58,2917,24,1521,0.410907622,1.260094581,0.767175868,2.129487992,0.580230833,DB0026810030124_,0.544329267,0.231186783,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,221361,DB00715,10030124,49,4794,16,2271,0.229952055,1.450688332,0.808852318,2.739191717,0.385933005,DB0071510030124_,0.952091486,0.372038156,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,paroxetine,DB00715
,221369,DB00231,10033775,36,3260,17,2122,0.32345049,1.378340434,0.752160533,2.623965966,0.491879784,DB0023110033775_,0.709520935,0.320880191,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,temazepam,DB00231
,221394,DB00737,10047895,69,2732,24,908,0.809535424,0.955535759,0.588725213,1.600265818,0.897384007,DB0073710047895_,0.108271407,-0.045483092,NA,10047895,Weight decreased,10022891,Investigations,Inv,meclizine,DB00737
,221489,DB00959,10022000,75,8003,35,4967,0.169341344,1.329919618,0.8776335,2.050662876,0.310021746,DB0095910022000_,1.171112835,0.285118503,NA,10022000,Influenza,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,221496,DB01136,10022004,45,9839,34,11081,0.089955002,1.490560472,0.932877745,2.401669705,0.195128305,DB0113610022004_,1.634097963,0.399152205,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,221543,DB06212,10005802,43,631,22,550,0.054595094,1.702934783,0.982232597,3.029362454,0.133612585,DB0621210005802_,2.01281082,0.532353105,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,tolvaptan,DB06212
,221556,DB00091,10022437,72,5438,15,2655,0.001746531,2.343303977,1.327721838,4.41047585,0.008693793,DB0009110022437_,4.745145922,0.851561889,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,cyclosporine,DB00091
,221569,DB06212,10053762,178,496,136,436,0.295399094,1.150367647,0.882181132,1.502121692,0.461307554,DB0621210053762_,0.773690313,0.140081585,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tolvaptan,DB06212
,221682,DB00115,10013395,32,18393,32,10440,0.026420888,0.567648031,0.336458641,0.957515988,0.07669151,DB0011510013395_,2.567964274,-0.566253716,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,221758,DB00316,10021639,72,65402,15,36938,0.000187,2.710930574,1.539328107,5.092529573,0.001362969,DB0031610021639_,6.598089896,0.997291961,NA,10021639,Incontinence,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,221919,DB01373,10029223,60,22660,13,7368,0.220012561,1.500660034,0.814135992,2.981900849,0.373448075,DB0137310029223_,0.984976307,0.405905034,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,calcium,DB01373
,222004,DB06643,10005396,96,52325,7,7508,0.09910427,1.967812974,0.918712313,5.027444695,0.209494379,DB0664310005396_,1.563058371,0.67692276,NA,10005396,Blood calcium increased,10022891,Investigations,Inv,denosumab,DB06643
,222008,DB06643,10057362,38,52383,19,7496,3.88538515702566e-05,0.286228821,0.160852446,0.525890663,0.000356016,DB0664310057362_,7.940533859,-1.250963715,male,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,222037,DB00588,10040829,55,16469,27,8441,0.90738462,1.044058192,0.646893323,1.722899474,0.958745315,DB0058810040829_,0.042129813,0.043115228,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,222051,DB06643,10073317,470,51951,60,7455,0.42931297,1.124114212,0.856801423,1.497953545,0.597831069,DB0664310073317_,0.514447059,0.116995359,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,222065,DB06643,10005483,40,52381,21,7494,8.77904998887057e-06,0.272496048,0.156803889,0.486800848,9.68957921299446e-05,DB0664310005483_,9.241874465,-1.300131166,male,10005483,Blood creatinine increased,10022891,Investigations,Inv,denosumab,DB06643
,222069,DB06605,10006002,52,14021,10,13023,2.63545347934984e-07,4.829512311,2.426803409,10.65997467,4.34858096074767e-06,DB0660510006002_,12.34566098,1.574745492,female,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,222072,DB06605,10016322,202,13871,112,12921,8.68449768424609e-06,1.680008871,1.325331414,2.13853127,9.60121641964344e-05,DB0660510016322_,9.251035664,0.518799074,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,222275,DB00215,10042682,41,11062,11,5265,0.101822289,1.773953832,0.894618891,3.830057168,0.213676009,DB0021510042682_,1.543294386,0.573210859,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,222292,DB00343,10006784,45,8691,14,5081,0.041797413,1.879081339,1.011679557,3.710597771,0.10931791,DB0034310006784_,2.213495034,0.630783008,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,222304,DB00758,10007554,28,8272,64,10010,0.004432499,0.529445619,0.326560726,0.83849034,0.018547838,DB0075810007554_,3.987402037,-0.635924822,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,222314,DB01275,10033425,77,3902,49,3300,0.125969076,1.328935878,0.91400716,1.94823153,0.250035655,DB0127510033425_,1.386151753,0.28437853,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,hydralazine,DB01275
,222399,DB00355,10053762,105,1688,55,1208,0.069842815,1.366084461,0.967881344,1.945890289,0.160994335,DB0035510053762_,1.826386102,0.31194859,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,aztreonam,DB00355
,222400,DB06605,10038435,98,13975,102,12931,0.434813959,0.889013554,0.666103584,1.186038391,0.603277113,DB0660510038435_,0.50537863,-0.117642797,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,apixaban,DB06605
,222428,DB00571,10013710,37,5086,59,2550,2.58094192437405e-08,0.31447365,0.202046423,0.483800945,5.28555188797599e-07,DB0057110013710_,14.45311861,-1.156854989,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,222442,DB00490,10070863,179,3891,66,1510,0.771096344,1.05249681,0.784118205,1.426915987,0.874689322,DB0049010070863_,0.133886516,0.051165256,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,buspirone,DB00490
,222443,DB00571,10070863,288,4835,186,2423,0.010491466,0.77600429,0.638784172,0.944338713,0.036986077,DB0057110070863_,3.297213724,-0.25359723,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,propranolol,DB00571
,222444,DB00660,10070863,171,1086,65,302,0.052980039,0.731726198,0.530697409,1.017392824,0.130605424,DB0066010070863_,2.035574533,-0.312348881,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,metaxalone,DB00660
,222501,DB06210,10037844,34,1426,28,1033,0.696310143,0.879680344,0.514109188,1.516315106,0.817295352,DB0621010037844_,0.201754742,-0.128196683,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,eltrombopag,DB06210
,222573,DB01033,10033645,17,1165,38,1266,0.013663359,0.486288964,0.255916171,0.888319987,0.045660339,DB0103310033645_,3.086525224,-0.720952256,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,mercaptopurine,DB01033
,222605,DB01267,10010264,81,2771,99,3616,0.703196264,1.067659344,0.782587212,1.453161678,0.82194614,DB0126710010264_,0.19608041,0.065468724,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,222652,DB00051,10024264,35,25696,32,11388,0.003417272,0.484726444,0.291329672,0.809153507,0.015033135,DB0005110024264_,4.197498492,-0.72417058,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,222726,DB00471,10019974,68,14121,11,5454,0.005236456,2.387539208,1.252585734,5.010360736,0.021230951,DB0047110019974_,3.852295189,0.870263216,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,montelukast,DB00471
,222758,DB00028,10053664,171,13287,47,5568,0.010849866,1.524648769,1.096391677,2.15635705,0.038007426,DB0002810053664_,3.269973726,0.421764068,NA,10053664,Infusion site pruritus,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,222801,DB00620,10022000,53,4775,21,3111,0.05590944,1.644209901,0.972816796,2.875841035,0.135921166,DB0062010022000_,1.995680226,0.497259965,NA,10022000,Influenza,10021881,Infections and infestations,Infec,triamcinolone,DB00620
,222802,DB00646,10022000,48,3405,33,1967,0.486091786,0.840296674,0.526309541,1.356185296,0.649960453,DB0064610022000_,0.430843759,-0.174000267,NA,10022000,Influenza,10021881,Infections and infestations,Infec,nystatin,DB00646
,222803,DB00836,10022000,57,5478,44,4031,0.839915499,0.953298088,0.630577767,1.449628585,0.918046361,DB0083610022000_,0.085507387,-0.047827635,NA,10022000,Influenza,10021881,Infections and infestations,Infec,loperamide,DB00836
,222805,DB01225,10022000,35,5009,34,4606,0.903870972,0.946571526,0.572307476,1.567278642,0.95743432,DB0122510022000_,0.043498156,-0.054908742,NA,10022000,Influenza,10021881,Infections and infestations,Infec,enoxaparin,DB01225
,222974,DB01281,10046306,181,8751,32,1766,0.577963347,1.141448563,0.777474145,1.724649297,0.726797704,DB0128110046306_,0.319107101,0.132298125,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,abatacept,DB01281
,222987,DB06186,10060933,45,2164,94,3552,0.214946443,0.785822906,0.535921828,1.137575841,0.36736352,DB0618610060933_,1.001403403,-0.241023822,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,ipilimumab,DB06186
,223008,DB00813,10023232,46,10526,21,10147,0.004532896,2.11152393,1.233843521,3.727732547,0.018883774,DB0081310023232_,3.969452253,0.747409928,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,fentanyl,DB00813
,223034,DB06724,10028391,66,7863,10,3909,0.000115748,3.280859027,1.674180781,7.166693118,0.000904005,DB0672410028391_,7.008675159,1.188105287,female,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium carbonate,DB06724
,223102,DB01377,10040753,41,3755,11,2659,0.002753061,2.638994443,1.329109406,5.703699759,0.012601516,DB0137710040753_,4.373938142,0.970397952,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,magnesium oxide,DB01377
,223152,DB00924,10005557,58,10104,29,4222,0.479142882,0.835739532,0.525562489,1.355973237,0.644307088,DB0092410005557_,0.439579821,-0.179438279,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,cyclobenzaprine,DB00924
,223161,DB00193,10056819,53,19267,9,8693,0.003689717,2.656908108,1.298449883,6.12961326,0.015988163,DB0019310056819_,4.135906627,0.977163081,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,223172,DB00641,10056819,40,14084,32,12443,0.723575225,1.104325176,0.676000533,1.817491522,0.837498615,DB0064110056819_,0.177335669,0.099234448,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,223193,DB01276,10046735,61,1956,25,1486,0.010766243,1.853382965,1.139874043,3.096977702,0.037764821,DB0127610046735_,3.276377268,0.617012599,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,exenatide,DB01276
,223194,DB01281,10060933,183,8749,32,1766,0.518551575,1.15432388,0.786530174,1.743571932,0.677830797,DB0128110060933_,0.388857584,0.143514787,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,223250,DB01050,10000496,40,18068,11,9360,0.074827049,1.883753179,0.948037575,4.072490969,0.169554224,DB0105010000496_,1.774582499,0.633266159,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,223282,DB00222,10018884,36,3170,42,3086,0.49445282,0.834455043,0.517913162,1.338289392,0.656954275,DB0022210018884_,0.42014086,-0.18097641,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,glimepiride,DB00222
,223295,DB00678,10057362,38,15561,28,10696,0.802677112,0.932847875,0.557226035,1.579203099,0.893298384,DB0067810057362_,0.112834617,-0.069513141,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,223321,DB00698,10037660,69,3079,15,414,0.122867152,0.618613971,0.346389741,1.175641272,0.245519468,DB0069810037660_,1.404379036,-0.480273833,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,nitrofurantoin,DB00698
,223350,DB01593,10013968,49,1084,29,669,0.905616567,1.04276552,0.638551944,1.7301751,0.957861963,DB0159310013968_,0.0430516,0.041876338,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zinc,DB01593
,223356,DB00381,10014011,58,29302,15,22872,4.45022323404527e-05,3.018034405,1.687747262,5.735430549,0.000400185,DB0038110014011_,7.823583257,1.10460576,female,10014011,Ear infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,223377,DB00196,10040753,106,4977,19,3266,5.00423386438418e-09,3.660534241,2.227180281,6.332094981,1.20124463128163e-07,DB0019610040753_,15.93473744,1.297609104,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,fluconazole,DB00196
,223382,DB00448,10040753,99,5046,34,3090,0.003743268,1.782949461,1.193175882,2.723026138,0.016167529,DB0044810040753_,4.124750441,0.578268994,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,lansoprazole,DB00448
,223389,DB00646,10040753,71,3382,15,1985,0.000107876,2.777692121,1.570877322,5.236800586,0.000850996,DB0064610040753_,7.06910307,1.021620411,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,nystatin,DB00646
,223425,DB00115,10061520,43,18382,17,10455,0.22760556,1.438618271,0.803134844,2.691932824,0.382887178,DB0011510061520_,0.960014908,0.363683119,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,223429,DB00381,10061520,42,29318,26,22861,0.393061224,1.259605716,0.754242693,2.140621192,0.563030751,DB0038110061520_,0.574421032,0.230798748,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,223432,DB00471,10061520,40,14149,14,5451,0.879371139,1.100727416,0.585731836,2.192290291,0.949348846,DB0047110061520_,0.051978954,0.095971248,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,223440,DB00761,10061520,38,15269,12,8613,0.078488941,1.786225768,0.91316286,3.756534592,0.175841925,DB0076110061520_,1.738169843,0.580104884,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,223560,DB09270,10000081,53,3061,19,2349,0.003823811,2.140331415,1.242454697,3.839687643,0.016447205,DB0927010000081_,4.107599706,0.760960684,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ubidecarenone,DB09270
,223657,DB00455,10008531,82,9319,51,5067,0.466322756,0.874242486,0.60785714,1.267768298,0.633093464,DB0045510008531_,0.457137215,-0.134397498,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,223700,DB00169,10013789,37,38654,14,18161,0.550301525,1.241674604,0.655467229,2.487008866,0.704614346,DB0016910013789_,0.350104653,0.216460955,NA,10013789,Dry throat,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,223714,DB00213,10013946,165,18730,73,13348,0.000579431,1.610766188,1.214499997,2.153941219,0.003491598,DB0021310013946_,5.657395729,0.476709959,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,223722,DB01137,10013946,33,7739,21,5572,0.68138212,1.131363528,0.634608235,2.060249741,0.807399032,DB0113710013946_,0.21393727,0.123423567,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,223724,DB09153,10013946,39,7760,16,5683,0.055082194,1.785012102,0.973645758,3.425126654,0.134500508,DB0915310013946_,2.006187305,0.579425195,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,sodium chloride,DB09153
,223831,DB00455,10021789,90,9311,37,5081,0.16195669,1.327354668,0.894309426,2.005855806,0.300012799,DB0045510021789_,1.203930143,0.28318799,NA,10021789,Infection,10021881,Infections and infestations,Infec,loratadine,DB00455
,223847,DB01137,10022004,34,7738,21,5572,0.681560815,1.165809942,0.656629388,2.116382862,0.807446975,DB0113710022004_,0.213877892,0.153416075,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,223856,DB00425,10022061,67,12628,18,7466,0.002196891,2.200594314,1.291136033,3.938796008,0.010500096,DB0042510022061_,4.556370913,0.788727466,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,223864,DB09270,10022061,41,3073,11,2357,0.001076525,2.858271916,1.439065829,6.17989344,0.005854844,DB0927010022061_,5.140485871,1.050217217,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,223890,DB01076,10024384,31,25716,28,25555,0.794788475,1.10019589,0.638352305,1.904301625,0.88886159,DB0107610024384_,0.117813747,0.095488245,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,atorvastatin,DB01076
,223931,DB01137,10025482,169,7603,95,5498,0.051047609,1.286395641,0.992158383,1.676061737,0.126979739,DB0113710025482_,2.063727744,0.251844231,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,223943,DB01225,10028411,31,5013,20,4620,0.26086017,1.428429609,0.787377476,2.648334232,0.422362491,DB0122510028411_,0.861891349,0.356575665,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,enoxaparin,DB01225
,223944,DB09153,10028411,55,7744,18,5681,0.002713558,2.241412402,1.294445366,4.061152569,0.012454315,DB0915310028411_,4.385688168,0.807106204,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sodium chloride,DB09153
,223955,DB00213,10028836,93,18802,36,13385,0.001637553,1.839015034,1.238376682,2.784387501,0.008252123,DB0021310028836_,4.79728476,0.609230121,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,223975,DB01076,10030041,46,25701,33,25550,0.17645198,1.385735441,0.866723867,2.237817602,0.319281334,DB0107610030041_,1.141682641,0.326231003,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,atorvastatin,DB01076
,224016,DB00126,10047461,43,10128,13,5932,0.036953772,1.937251582,1.021498974,3.93043447,0.099492114,DB0012610047461_,2.307676895,0.661270258,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,224022,DB00455,10047461,35,9366,16,5102,0.660216514,1.191570623,0.641610096,2.308127494,0.792537212,DB0045510047461_,0.232515819,0.175272288,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,loratadine,DB00455
,224030,DB13961,10047461,40,9417,26,6388,0.900645079,1.04361362,0.620680276,1.783142035,0.95675912,DB1396110047461_,0.044203623,0.042689326,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,fish oil,DB13961
,224036,DB00433,10047571,49,7607,17,6003,0.002665469,2.274420742,1.285566583,4.217315563,0.012276477,DB0043310047571_,4.400070247,0.821725401,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,prochlorperazine,DB00433
,224041,DB01137,10047571,41,7731,29,5564,1,1.017506403,0.61633323,1.699990814,1,DB0113710047571_,0,0.017354931,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,levofloxacin,DB01137
,224126,DB13961,10061218,41,9416,11,6403,0.0043237,2.534445765,1.278237802,5.471793304,0.018198731,DB1396110061218_,4.006403387,0.92997498,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,224189,DB00564,10007515,48,2556,15,1448,0.046889898,1.812591342,0.993522109,3.497862112,0.119243514,DB0056410007515_,2.126587543,0.594757502,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,carbamazepine,DB00564
,224199,DB00472,10009033,49,10710,25,4287,0.366373089,0.784541991,0.474576148,1.32744994,0.535959297,DB0047210009033_,0.62369706,-0.242655182,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,224265,DB01611,10049848,49,11864,8,2353,0.722658717,1.214761685,0.569567439,2.974113024,0.836750997,DB0161110049848_,0.178228747,0.194547914,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,hydroxychloroquine,DB01611
,224308,DB00005,10057362,1488,126594,754,41665,1.04946017083024e-20,0.649518104,0.594200181,0.710458926,1.1813730445513e-18,DB0000510057362_,41.27985431,-0.431524569,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,224310,DB00490,10000081,47,4023,19,1557,0.890414647,0.957381863,0.549183795,1.733143287,0.954638381,DB0049010000081_,0.046422669,-0.043552947,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,buspirone,DB00490
,224331,DB01224,10021789,41,8067,21,5896,0.199192783,1.426917613,0.822941842,2.544616402,0.348065966,DB0122410021789_,1.05536326,0.355516603,NA,10021789,Infection,10021881,Infections and infestations,Infec,quetiapine,DB01224
,224552,DB01016,10069339,22,1079,45,1183,0.018031825,0.536150831,0.304479621,0.918628044,0.05693118,DB0101610069339_,2.865912113,-0.623339757,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,glyburide,DB01016
,224606,DB00654,10015958,96,3720,46,2552,0.047092739,1.431618865,0.993355901,2.089173348,0.119637815,DB0065410015958_,2.123286308,0.358805877,NA,10015958,Eye pain,10015919,Eye disorders,Eye,latanoprost,DB00654
,224613,DB00484,10069327,45,2462,25,1755,0.331391452,1.283029609,0.766815452,2.192133919,0.500165043,DB0048410069327_,0.692817149,0.249224164,NA,10069327,Product quality issue,10077536,Product issues,Prod,brimonidine,DB00484
,224614,DB00654,10069327,71,3745,33,2565,0.070123014,1.473514692,0.958784535,2.306832597,0.16144908,DB0065410069327_,1.823565478,0.387650494,NA,10069327,Product quality issue,10077536,Product issues,Prod,latanoprost,DB00654
,224623,DB00065,10076309,374,9090,255,4702,0.001089404,0.758704948,0.642718653,0.89665341,0.005911324,DB0006510076309_,5.130885452,-0.276142315,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,infliximab,DB00065
,224624,DB00455,10076309,129,9272,65,5053,0.650202518,1.08156595,0.794985708,1.48362164,0.784907375,DB0045510076309_,0.242189562,0.078409945,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,224668,DB00635,10051076,34,33019,16,23778,0.196478799,1.530264837,0.821688982,2.969720295,0.34471889,DB0063510051076_,1.065026007,0.425440816,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,224676,DB00186,10076308,97,16804,45,9963,0.191787559,1.278015232,0.887766013,1.864483611,0.33891129,DB0018610076308_,1.082016887,0.245308275,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,224690,DB08900,10047895,42,969,21,416,0.576435292,0.858722314,0.490129596,1.546497715,0.725668797,DB0890010047895_,0.32066157,-0.152309676,NA,10047895,Weight decreased,10022891,Investigations,Inv,teduglutide,DB08900
,224760,DB08868,10037087,93,9109,22,2489,0.647722018,1.155071478,0.717918647,1.935498661,0.78282977,DB0886810037087_,0.244840014,0.144162228,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,fingolimod,DB08868
,224761,DB08868,10046735,50,9152,8,2503,0.198387576,1.709226518,0.802647498,4.180384215,0.347155145,DB0886810046735_,1.057983495,0.53604094,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,fingolimod,DB08868
,224788,DB00402,10016256,108,1244,42,654,0.127661617,1.351669973,0.925338941,2.004960696,0.252328127,DB0040210016256_,1.377024948,0.301340845,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,eszopiclone,DB00402
,224790,DB00341,10024264,42,11363,27,5041,0.149940554,0.690107175,0.415158046,1.165368479,0.283834753,DB0034110024264_,1.259363066,-0.370908368,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,224808,DB00715,10007617,35,4808,34,2253,0.002786207,0.482417651,0.291386184,0.799523349,0.012725536,DB0071510007617_,4.364144558,-0.728945044,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,paroxetine,DB00715
,224826,DB00448,10038435,194,4951,176,2948,9.39707035807235e-05,0.656392544,0.529643711,0.813821549,0.000756283,DB0044810038435_,7.187095049,-0.420996279,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,lansoprazole,DB00448
,224837,DB00863,10061024,49,10624,31,5809,0.558251894,0.864280437,0.539518643,1.403781592,0.711225603,DB0086310061024_,0.340765596,-0.145857983,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,ranitidine,DB00863
,224844,DB00448,10061481,217,4928,146,2978,0.346667962,0.898188778,0.721115181,1.121260752,0.516094664,DB0044810061481_,0.661465074,-0.107375013,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,lansoprazole,DB00448
,224848,DB00863,10061481,48,10625,31,5809,0.48043294,0.846565733,0.527245637,1.377463665,0.645216627,DB0086310061481_,0.438169163,-0.166567428,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,ranitidine,DB00863
,224871,DB00999,10017853,39,21391,25,12214,0.6967839,0.890747166,0.525336179,1.536485947,0.817595858,DB0099910017853_,0.201387126,-0.115694656,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,224878,DB01043,10025482,40,1361,22,1388,0.020761852,1.853841366,1.069133751,3.293575324,0.063654298,DB0104310025482_,2.754288425,0.617259901,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,memantine,DB01043
,224900,DB01234,10061148,42,31583,38,32850,0.576530152,1.149598981,0.723255382,1.8326108,0.725770835,DB0123410061148_,0.320520968,0.139413169,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,224914,DB00295,10028810,80,14583,36,9566,0.070116792,1.457687141,0.971129402,2.226547874,0.161447129,DB0029510028810_,1.823577566,0.37685103,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,morphine,DB00295
,224931,DB01281,10040753,198,8734,26,1772,0.037318766,1.544987207,1.019641098,2.431692175,0.100218162,DB0128110040753_,2.300405851,0.43501563,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,abatacept,DB01281
,224973,DB00472,10027417,58,10701,30,4282,0.286579145,0.773620125,0.48889318,1.247306646,0.451359148,DB0047210027417_,0.795491919,-0.256674321,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,fluoxetine,DB00472
,225012,DB00472,10069339,80,10679,70,4242,2.720928725559e-06,0.453994136,0.324564347,0.636273419,3.47688923438592e-05,DB0047210069339_,10.26678747,-0.789670997,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,fluoxetine,DB00472
,225014,DB00879,10069339,19,1758,53,3659,0.311589385,0.746159602,0.415818612,1.285968527,0.479025691,DB0087910069339_,0.736001048,-0.292815758,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,emtricitabine,DB00879
,225066,DB00959,10007882,44,8034,26,4976,0.902311419,1.048161193,0.630370829,1.775693016,0.957195726,DB0095910007882_,0.043747388,0.047037384,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,225075,DB00572,10016322,40,2862,20,2106,0.188574404,1.471587523,0.837355593,2.665136715,0.334741057,DB0057210016322_,1.09439801,0.386341766,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,atropine,DB00572
,225114,DB01225,10010264,55,4989,39,4601,0.215154961,1.300541593,0.845504613,2.017590851,0.367590663,DB0122510010264_,1.00078529,0.262780788,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,225234,DB00215,10031161,46,11057,11,5265,0.045639134,1.99117903,1.014941984,4.26655425,0.116797259,DB0021510031161_,2.147315677,0.688726941,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,225323,DB00441,10016288,53,2221,58,1836,0.148355189,0.755448054,0.507768528,1.12189411,0.28173659,DB0044110016288_,1.266782721,-0.280444257,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,gemcitabine,DB00441
,225327,DB00813,10016288,41,10531,42,10126,0.826163975,0.938623338,0.594733265,1.480438319,0.90826551,DB0081310016288_,0.096218531,-0.063341012,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,fentanyl,DB00813
,225499,DB00059,10013968,31,796,29,1078,0.184781892,1.447363679,0.836266473,2.511421561,0.329902668,DB0005910013968_,1.108957613,0.369743749,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pegaspargase,DB00059
,225502,DB00059,10033645,22,805,40,1067,0.296547152,0.72912303,0.409247582,1.268116728,0.462403861,DB0005910033645_,0.771316612,-0.315912796,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,pegaspargase,DB00059
,225513,DB01012,10013950,53,10579,38,8647,0.597822304,1.139998415,0.73674756,1.779210247,0.742861971,DB0101210013950_,0.297245024,0.131026872,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,cinacalcet,DB01012
,225538,DB00996,10066901,81,38872,55,22370,0.372751085,0.847532154,0.594162301,1.21684778,0.542466698,DB0099610066901_,0.611628581,-0.165426501,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,225569,DB00656,10000060,74,11939,26,6593,0.046794421,1.571678075,0.992093408,2.56339284,0.119059638,DB0065610000060_,2.128130753,0.452143886,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,225570,DB00697,10000060,42,6054,11,1795,0.869682772,1.132065704,0.5713432,2.443306104,0.942081668,DB0069710000060_,0.059663312,0.12404402,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,tizanidine,DB00697
,225656,DB01240,10059168,67,5684,20,1556,0.695483499,0.917064358,0.547603616,1.60093335,0.816689768,DB0124010059168_,0.202495977,-0.086577626,NA,10059168,Oxygen consumption increased,10022891,Investigations,Inv,epoprostenol,DB01240
,225657,DB06403,10059168,99,21372,20,6641,0.083684551,1.538076897,0.943522196,2.628748354,0.184565232,DB0640310059168_,1.689752319,0.430532868,NA,10059168,Oxygen consumption increased,10022891,Investigations,Inv,ambrisentan,DB06403
,225724,DB01164,10039906,30,6494,40,7896,0.719912558,0.911895856,0.547805116,1.50315677,0.834674324,DB0116410039906_,0.180713661,-0.092229489,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,calcium chloride,DB01164
,225768,DB00333,10010144,286,2785,183,2969,1.5197147477889e-07,1.665942844,1.368781577,2.031442039,2.65684749887804e-06,DB0033310010144_,12.83837029,0.510391236,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,methadone,DB00333
,225769,DB00813,10010144,309,10263,186,9982,2.44692327846167e-07,1.615758258,1.339748135,1.952863718,4.07129817787669e-06,DB0081310010144_,12.41154865,0.479804356,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,fentanyl,DB00813
,225787,DB00188,10048908,44,7842,31,8797,0.049001368,1.592144601,0.981861772,2.610939949,0.123124076,DB0018810048908_,2.094562684,0.465081913,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,bortezomib,DB00188
,225788,DB00399,10048908,38,6954,22,4976,0.511986653,1.23594431,0.7115702,2.196931135,0.672256622,DB0039910048908_,0.397115134,0.211835301,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,zoledronic acid,DB00399
,225789,DB00480,10048908,347,67081,226,67436,3.69726457175885e-07,1.543509886,1.301168073,1.833909778,5.89163984654025e-06,DB0048010048908_,12.04197619,0.43405897,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,lenalidomide,DB00480
,225791,DB00787,10048908,90,16910,64,17184,0.029297762,1.429014227,1.024984745,2.002301385,0.083154269,DB0078710048908_,2.487057735,0.356984855,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,acyclovir,DB00787
,225807,DB01275,10000059,30,3949,34,3315,0.257308692,0.740729878,0.436861298,1.250151933,0.418175346,DB0127510000059_,0.871854447,-0.300119258,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,hydralazine,DB01275
,225809,DB00421,10005734,62,8841,49,5203,0.13874324,0.744677689,0.502875372,1.108018979,0.268023816,DB0042110005734_,1.316679435,-0.294803787,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,spironolactone,DB00421
,225814,DB01118,10005734,21,3042,35,4674,0.890986959,0.921891217,0.508901155,1.631982327,0.954745791,DB0111810005734_,0.046310162,-0.081328048,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,amiodarone,DB01118
,225848,DB01118,10020646,18,3045,38,4671,0.276381142,0.726655976,0.389617543,1.307705964,0.439829436,DB0111810020646_,0.821368274,-0.319302123,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,amiodarone,DB01118
,225863,DB01020,10038435,18,1795,32,1846,0.065167554,0.578568751,0.304588497,1.066743655,0.152728737,DB0102010038435_,1.879091891,-0.547197897,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,isosorbide mononitrate,DB01020
,225873,DB01118,10069339,130,2933,164,4545,0.088618991,1.228303049,0.963517486,1.563346492,0.192954829,DB0111810069339_,1.645299163,0.205633582,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,amiodarone,DB01118
,225876,DB00421,10070863,47,8856,67,5185,3.33212568306443e-06,0.410733284,0.276240229,0.606337972,4.14897790522731e-05,DB0042110070863_,10.09006345,-0.889811219,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,spironolactone,DB00421
,225905,DB00476,10015958,47,17210,11,6166,0.233788428,1.530750399,0.781920744,3.27520448,0.390551261,DB0047610015958_,0.940196047,0.425758072,NA,10015958,Eye pain,10015919,Eye disorders,Eye,duloxetine,DB00476
,225967,DB00451,10064848,219,47052,71,15348,1,1.006142912,0.766047307,1.33509834,1,DB0045110064848_,0,0.006124122,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,225968,DB00635,10064848,121,32932,78,23716,0.472098157,1.117187243,0.833136884,1.505420456,0.638154374,DB0063510064848_,0.44917506,0.110814137,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,225970,DB00736,10064848,668,9923,424,5129,0.001536513,0.814354778,0.716517091,0.926244562,0.007848279,DB0073610064848_,4.847460949,-0.205359163,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,esomeprazole,DB00736
,225971,DB01076,10064848,193,25554,155,25428,0.052670305,1.239014182,0.996978835,1.541865379,0.13004039,DB0107610064848_,2.039910185,0.214316049,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,225973,DB08932,10064848,64,19379,16,6581,0.304785791,1.358342183,0.775480325,2.519167934,0.471566957,DB0893210064848_,0.751694178,0.306264973,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,macitentan,DB08932
,225979,DB00381,10003662,20,29340,33,22854,0.008095684,0.472085083,0.256648108,0.847701594,0.03008129,DB0038110003662_,3.503851908,-0.750596049,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,amlodipine,DB00381
,225987,DB00112,10043607,34,5899,22,4069,0.891921862,1.066024199,0.604651865,1.916263906,0.955033654,DB0011210043607_,0.046008699,0.063936026,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,bevacizumab,DB00112
,225991,DB01592,10013786,37,6239,15,3052,0.657153465,1.206600851,0.645222446,2.370380626,0.790458112,DB0159210013786_,0.235142613,0.187807192,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,iron,DB01592
,226008,DB04868,10028334,32,1609,27,1489,0.79301448,1.096736991,0.633182639,1.912798648,0.887807381,DB0486810028334_,0.119000473,0.092339399,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,nilotinib,DB04868
,226013,DB01046,10012735,47,838,18,310,0.886521271,0.965950473,0.540662309,1.795771654,0.952802388,DB0104610012735_,0.048347754,-0.034642716,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lubiprostone,DB01046
,226018,DB00158,10013911,55,16760,26,8078,1,1.019587257,0.628050724,1.695241536,1,DB0015810013911_,0,0.019397896,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,folic acid,DB00158
,226060,DB05676,10018836,55,47074,32,25297,0.736345035,0.923637967,0.586682353,1.476406541,0.847745865,DB0567610018836_,0.165174375,-0.079435095,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,226076,DB01017,10047700,35,1434,19,882,0.777017924,1.132978702,0.626066816,2.110569472,0.878512755,DB0101710047700_,0.129524852,0.124850184,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,minocycline,DB01017
,226099,DB01212,10069339,80,1939,125,1816,0.000545459,0.599484248,0.443645538,0.806242756,0.003316921,DB0121210069339_,5.708718208,-0.51168558,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ceftriaxone,DB01212
,226141,DB00572,10000059,44,2858,28,2098,0.631239983,1.153496454,0.699654399,1.930927124,0.770079966,DB0057210000059_,0.261260917,0.142797725,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,atropine,DB00572
,226190,DB00697,10037153,66,6030,17,1789,0.694024025,1.151807616,0.665875481,2.09996694,0.815795966,DB0069710037153_,0.203590997,0.141332549,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,tizanidine,DB00697
,226192,DB01039,10037153,63,2910,58,2993,0.582049962,1.117166949,0.766503233,1.630706392,0.730218993,DB0103910037153_,0.314410799,0.110795971,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,fenofibrate,DB01039
,226194,DB00193,10042609,101,19219,32,8670,0.090588037,1.423851365,0.947459325,2.192473163,0.1961659,DB0019310042609_,1.628794547,0.353365429,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,tramadol,DB00193
,226197,DB00788,10042609,42,9314,22,5039,1,1.032843041,0.601938496,1.818832066,1,DB0078810042609_,0,0.032315234,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,naproxen,DB00788
,226229,DB09027,10047895,52,5127,50,7102,0.069959846,1.440555668,0.956392347,2.171771629,0.161214618,DB0902710047895_,1.825018768,0.365028919,NA,10047895,Weight decreased,10022891,Investigations,Inv,ledipasvir,DB09027
,226305,DB00115,10007697,41,18384,10,10462,0.01285481,2.333172882,1.148728706,5.225714493,0.043486318,DB0011510007697_,3.135308914,0.847229093,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,226366,DB00254,10018884,36,5899,28,3360,0.240666545,0.732375293,0.433704511,1.24839428,0.398671506,DB0025410018884_,0.919617493,-0.311462201,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,doxycycline,DB00254
,226391,DB00115,10025256,59,18366,13,10459,0.00123717,2.584463178,1.400543724,5.139011502,0.006557574,DB0011510025256_,5.027134566,0.949517818,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,226445,DB00331,10027374,30,24916,32,20720,0.372002063,0.779628063,0.457477976,1.325316674,0.541676549,DB0033110027374_,0.613086229,-0.248938315,NA,10027374,Mental impairment,10029205,Nervous system disorders,Nerv,metformin,DB00331
,226472,DB00448,10033775,36,5109,21,3103,1,1.041185758,0.590429259,1.880772679,1,DB0044810033775_,0,0.040360215,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,lansoprazole,DB00448
,226489,DB01592,10038153,42,6234,17,3050,0.57932257,1.208694966,0.672182644,2.268572939,0.728070407,DB0159210038153_,0.317357522,0.189541237,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,iron,DB01592
,226517,DB00268,10047513,35,2940,15,1530,0.653151804,1.214204141,0.643775641,2.400909676,0.787292559,DB0026810047513_,0.239155361,0.194088834,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ropinirole,DB00268
,226564,DB00115,10058920,47,18378,20,10452,0.31004485,1.336487235,0.776194994,2.382637491,0.477492763,DB0011510058920_,0.739206274,0.290044705,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,226569,DB00268,10058920,60,2915,19,1526,0.056231667,1.652986781,0.968622427,2.944404463,0.13652144,DB0026810058920_,1.991273604,0.502583822,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,ropinirole,DB00268
,226572,DB00722,10058920,33,25370,19,26013,0.051321769,1.780830329,0.983090999,3.315798724,0.127485962,DB0072210058920_,2.059749021,0.577079733,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,226583,DB05679,10000081,71,6860,46,4863,0.706210079,1.094173212,0.743106133,1.624977515,0.824058063,DB0567910000081_,0.193514286,0.089999021,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ustekinumab,DB05679
,226585,DB05676,10029410,37,47092,20,25309,1,0.994258241,0.562153378,1.80832126,1,DB0567610029410_,0,-0.005758306,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,226614,DB05676,10006784,63,47066,29,25300,0.513868344,1.167746155,0.74081869,1.881180444,0.673835341,DB0567610006784_,0.394769499,0.155075528,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,226697,DB00698,10028334,51,3097,8,421,0.685485596,0.866654627,0.404574466,2.129575341,0.810091981,DB0069810028334_,0.21060748,-0.143114736,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,nitrofurantoin,DB00698
,226717,DB06637,10034701,47,6115,14,2005,0.881666205,1.100734198,0.594246388,2.169536752,0.950483399,DB0663710034701_,0.050784582,0.09597741,NA,10034701,Peroneal nerve palsy,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,226785,DB05676,10046735,209,46920,83,25246,0.019367549,1.35488055,1.045312863,1.769851984,0.060273012,DB0567610046735_,2.808870834,0.303713295,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,226872,DB00471,10029354,59,14130,43,5422,0.001802744,0.526492362,0.348963484,0.800159688,0.008932161,DB0047110029354_,4.7180969,-0.641518454,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,montelukast,DB00471
,226874,DB00588,10029354,72,16452,55,8413,0.030208253,0.669415398,0.464252792,0.969918228,0.085145453,DB0058810029354_,2.463394277,-0.401350488,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,fluticasone propionate,DB00588
,226902,DB09146,10046735,56,732,18,409,0.044987856,1.737584357,0.990254133,3.185422155,0.115546784,DB0914610046735_,2.158079774,0.552495848,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,iron sucrose,DB09146
,226947,DB00186,10013654,93,16808,106,9902,4.20655131736511e-06,0.516872764,0.386555625,0.690198591,5.07430937939155e-05,DB0018610013654_,9.888735032,-0.659958539,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,226950,DB00186,10027951,39,16862,15,9993,0.161435843,1.540825405,0.829933823,3.010402859,0.299385552,DB0018610027951_,1.206023064,0.43231825,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,226979,DB01281,10028810,140,8792,16,1782,0.030105857,1.773396624,1.051288658,3.196438424,0.084925138,DB0128110028810_,2.465985135,0.572896704,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,abatacept,DB01281
,227001,DB00381,10066274,34,29326,37,22850,0.187666153,0.716008815,0.435797188,1.173033066,0.333663909,DB0038110066274_,1.097621053,-0.334062801,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,amlodipine,DB00381
,227029,DB00476,10070863,301,16956,176,6001,3.17166713651075e-07,0.605291382,0.499675071,0.735003567,5.1381985012749e-06,DB0047610070863_,12.17880803,-0.502045314,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,227038,DB00490,10020642,55,4015,21,1555,1,1.014353053,0.601247118,1.772051195,1,DB0049010020642_,0,0.014251023,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,buspirone,DB00490
,227242,DB00928,10003549,15,820,44,1242,0.029991527,0.516501388,0.265193016,0.953608231,0.084693519,DB0092810003549_,2.468716194,-0.660677303,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,azacitidine,DB00928
,227244,DB09035,10003549,66,4660,110,6580,0.316290148,0.847236459,0.613259557,1.162835273,0.483972904,DB0903510003549_,0.725726358,-0.165775451,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,nivolumab,DB09035
,227249,DB09035,10016256,172,4554,242,6448,0.959494532,1.006340944,0.819703055,1.233401358,0.997145943,DB0903510016256_,0.002858137,0.006320925,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,nivolumab,DB09035
,227316,DB00656,10005734,31,11982,19,6600,0.767669481,0.898724545,0.491463251,1.685264732,0.872420225,DB0065610005734_,0.136484062,-0.106778694,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,trazodone,DB00656
,227375,DB08868,10013036,59,9143,24,2487,0.106570727,0.668720737,0.408657188,1.126507197,0.220968095,DB0886810013036_,1.509736953,-0.402388739,NA,10013036,Diplopia,10015919,Eye disorders,Eye,fingolimod,DB08868
,227433,DB08868,10017885,44,9158,7,2504,0.230536896,1.718552883,0.766674886,4.528481434,0.386544337,DB0886810017885_,0.950508703,0.54148259,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,fingolimod,DB08868
,227452,DB00193,10029223,53,19267,25,8677,0.902523974,0.954755837,0.582504539,1.604497041,0.957195726,DB0019310029223_,0.043747388,-0.04629964,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,227467,DB11133,10033775,45,2386,8,1566,0.000176302,3.690873346,1.715880914,9.09034746,0.001296435,DB1113310033775_,6.648137452,1.305863109,female,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,omega-3 fatty acids,DB11133
,227535,DB00736,10054112,97,10494,79,5474,0.003981409,0.640481192,0.47009078,0.874920847,0.017016476,DB0073610054112_,4.07357321,-0.445535522,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,esomeprazole,DB00736
,227545,DB06262,10005746,140,3660,182,4132,0.231542517,0.868447598,0.688473093,1.093631985,0.387809925,DB0626210005746_,0.947239945,-0.141048032,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,droxidopa,DB06262
,227655,DB00437,10007515,32,6889,88,11458,0.013814468,0.6048271,0.389932306,0.917057177,0.046059907,DB0043710007515_,3.077812399,-0.502812647,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,allopurinol,DB00437
,227659,DB00997,10007515,36,5295,19,3495,0.490687245,1.250590139,0.697272872,2.312179016,0.653918724,DB0099710007515_,0.424772211,0.223615551,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,doxorubicin,DB00997
,227777,DB00888,10037087,100,577,112,653,1,1.010454531,0.745987127,1.367406113,1,DB0088810037087_,0,0.01040026,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,mechlorethamine,DB00888
,227778,DB00973,10037087,110,3741,52,2969,0.002247102,1.678724979,1.191937896,2.390570228,0.010695353,DB0097310037087_,4.537945926,0.518034564,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ezetimibe,DB00973
,227836,DB00285,10000060,50,10901,10,3708,0.137659114,1.70062906,0.851293557,3.765148314,0.266438629,DB0028510000060_,1.322611345,0.530998218,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,227847,DB00924,10000060,65,10097,17,4234,0.089119659,1.603297719,0.927414019,2.9213351,0.193828161,DB0092410000060_,1.640783278,0.472062582,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,228060,DB00776,10013573,86,1819,36,1303,0.008420845,1.710953174,1.138603634,2.61730017,0.03102634,DB0077610013573_,3.472918769,0.537050627,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,oxcarbazepine,DB00776
,228092,DB01136,10008111,10,9874,58,11057,2.67727601488314e-08,0.193085856,0.087921293,0.3813199,5.45732454836784e-07,DB0113610008111_,14.42113699,-1.644620339,male,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,228094,DB00222,10028334,37,3169,28,3100,0.320993522,1.292601169,0.767779971,2.198663983,0.489247324,DB0022210028334_,0.714887143,0.256656598,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,glimepiride,DB00222
,228098,DB01307,10028334,37,2487,20,2049,0.141591988,1.524046836,0.858871826,2.780530834,0.272007703,DB0130710028334_,1.301924893,0.421369189,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin detemir,DB01307
,228215,DB09027,10016256,1279,3900,1974,5178,0.000315031,0.860253716,0.792002205,0.93421578,0.002101192,DB0902710016256_,6.165250707,-0.150527914,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,228236,DB00448,10014387,41,5104,21,3103,0.599657252,1.186976824,0.683883827,2.118437306,0.744262483,DB0044810014387_,0.295361507,0.17140959,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,lansoprazole,DB00448
,228262,DB01296,10010774,46,1403,26,957,0.467659104,1.206705295,0.724721999,2.048500828,0.634185603,DB0129610010774_,0.455413618,0.187893749,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,glucosamine,DB01296
,228270,DB01268,10030973,35,2108,30,3100,0.031143033,1.715456535,1.019690007,2.90236769,0.08722372,DB0126810030973_,2.439278966,0.539679246,NA,10030973,Oral discomfort,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,228287,DB01240,10039906,40,5711,15,1561,0.321954226,0.728920369,0.392740251,1.424356925,0.490256747,DB0124010039906_,0.712826052,-0.316190786,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,epoprostenol,DB01240
,228296,DB01050,10011781,57,18051,11,9360,0.001253667,2.686847941,1.393687561,5.68481415,0.006625645,DB0105010011781_,5.016807502,0.988368737,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,228309,DB01050,10054112,91,18017,54,9317,0.430004494,0.871458263,0.615029113,1.245197343,0.598495513,DB0105010054112_,0.513336252,-0.137587306,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,ibuprofen,DB01050
,228310,DB08896,10054112,45,778,54,986,0.835468957,1.056066944,0.686739986,1.617627229,0.914862473,DB0889610054112_,0.088981527,0.054551577,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,regorafenib,DB08896
,228342,DB06366,10053762,35,1703,18,65,2.03719630640461e-12,0.074546575,0.038650514,0.147503692,8.70694388843011e-11,DB0636610053762_,23.16431517,-2.596331187,male,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,pertuzumab,DB06366
,228354,DB00264,10033553,30,29577,30,24862,0.519013631,0.840590363,0.489409029,1.443676301,0.678264514,DB0026410033553_,0.388217928,-0.173650821,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,228408,DB00193,10048010,78,19242,33,8669,0.837348254,1.064873966,0.699729194,1.653452987,0.916179808,DB0019310048010_,0.087542637,0.062856451,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,228410,DB00316,10048010,170,65304,84,36869,0.32732708,1.142611752,0.874416427,1.502755894,0.495752942,DB0031610048010_,0.701677577,0.133316653,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,228413,DB00273,10048439,45,8436,8,2185,0.395770831,1.456868151,0.678377363,3.583813979,0.565432997,DB0027310048439_,0.570163475,0.376289029,NA,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,topiramate,DB00273
,228453,DB01238,10039906,107,5143,45,3457,0.0094032,1.598201461,1.114968026,2.323674998,0.033885811,DB0123810039906_,3.384758897,0.46887891,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,228500,DB00924,10042458,90,10072,27,4224,0.153593791,1.397962087,0.899036035,2.239708607,0.288929564,DB0092410042458_,1.241572342,0.335015524,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,228537,DB00047,10033295,30,9255,29,8489,0.896444446,0.948843235,0.549819118,1.639880474,0.956301489,DB0004710033295_,0.044682051,-0.052511684,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,228577,DB00328,10016256,32,728,45,770,0.243746433,0.752273873,0.457188776,1.22528878,0.402138777,DB0032810016256_,0.910958034,-0.284654829,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,indomethacin,DB00328
,228582,DB00331,10020765,51,24895,33,20719,0.274337577,1.286204526,0.81382427,2.058261637,0.437518625,DB0033110020765_,0.826636002,0.251695654,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,metformin,DB00331
,228596,DB00230,10048865,173,19501,107,8544,0.006093305,0.708382354,0.552645912,0.911424421,0.023963868,DB0023010048865_,3.731208092,-0.344771283,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,pregabalin,DB00230
,228599,DB00758,10048865,30,8270,21,10053,0.0659729,1.73649269,0.960844559,3.193854468,0.154114617,DB0075810048865_,1.87005869,0.551867384,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,clopidogrel,DB00758
,228695,DB01268,10012378,34,2109,35,3095,0.174270202,1.425463524,0.859545996,2.361705395,0.316521025,DB0126810012378_,1.150365611,0.354497041,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,sunitinib,DB01268
,228833,DB08908,10028810,65,10608,17,3262,0.603759528,1.175734034,0.679910027,2.142819976,0.747337482,DB0890810028810_,0.291238412,0.161892662,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,dimethyl fumarate,DB08908
,228886,DB05259,10042209,44,11226,10,2718,1,1.065337621,0.527378724,2.377154315,1,DB0525910042209_,0,0.063291764,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,glatiramer,DB05259
,228957,DB00889,10037844,44,736,18,499,0.084074239,1.656694638,0.925212624,3.083677303,0.185183842,DB0088910037844_,1.686406206,0.504824436,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,granisetron,DB00889
,229009,DB01101,10013946,58,7531,17,3891,0.037858163,1.762658844,1.010573936,3.233582289,0.101365165,DB0110110013946_,2.289025785,0.566823376,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,229032,DB00203,10043521,90,13788,25,8913,7.72315088672029e-05,2.327067973,1.478803929,3.787371414,0.000638575,DB0020310043521_,7.356271286,0.844609094,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,229045,DB08932,10002544,51,19392,9,6588,0.073936802,1.925190456,0.938029132,4.450590442,0.168073064,DB0893210002544_,1.783356492,0.655024901,NA,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,229100,DB00028,10074170,40,13418,15,5600,0.882269803,1.112924298,0.600937889,2.170599664,0.950859822,DB0002810074170_,0.050388628,0.106991054,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,229104,DB00316,10074170,93,65381,39,36914,0.123764201,1.346345895,0.916806914,2.01081312,0.246749244,DB0031610074170_,1.399382666,0.297394178,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,229135,DB06168,10003239,36,573,18,382,0.391550958,1.332963885,0.725007411,2.532346772,0.561387495,DB0616810003239_,0.577343891,0.287404948,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,canakinumab,DB06168
,229319,DB00005,10015137,37,128045,13,42406,0.870220914,0.942585673,0.489627205,1.932697814,0.94233451,DB0000510015137_,0.059394961,-0.059128464,NA,10015137,Eructation,10017947,Gastrointestinal disorders,Gastr,etanercept,DB00005
,229415,DB00019,10028334,45,18967,22,9507,1,1.025284011,0.602517545,1.793868446,1,DB0001910028334_,0,0.024969658,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,pegfilgrastim,DB00019
,229511,DB01234,10029350,47,31578,56,32832,0.554209515,0.872617109,0.579093229,1.309787892,0.707756449,DB0123410029350_,0.345655243,-0.136258411,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,229527,DB01248,10020751,37,2663,15,1359,0.5552145,1.2586902,0.67154168,2.477825588,0.708695551,DB0124810020751_,0.344329251,0.230071656,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,docetaxel,DB01248
,229601,DB00065,10008469,128,9336,56,4901,0.274713585,1.199860266,0.868157478,1.676661046,0.437945571,DB0006510008469_,0.825660643,0.182205105,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,229607,DB06674,10037844,185,4321,37,1453,0.003349413,1.681262713,1.169398483,2.474898562,0.014780376,DB0667410037844_,4.214454922,0.519545126,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,golimumab,DB06674
,229649,DB05676,10019974,117,47012,37,25292,0.003948025,1.701200469,1.166055098,2.534333346,0.016897149,DB0567610019974_,4.080610361,0.53133416,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,apremilast,DB05676
,229713,DB00864,10064675,40,6829,67,8325,0.119188934,0.727816451,0.478576062,1.094204672,0.240122721,DB0086410064675_,1.42660515,-0.31770639,NA,10064675,Graft versus host disease in skin,10021428,Immune system disorders,Immun,tacrolimus,DB00864
,229720,DB09038,10021097,18,2230,42,2499,0.008886954,0.48035361,0.259448434,0.855626846,0.032391815,DB0903810021097_,3.429849515,-0.733232758,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,empagliflozin,DB09038
,229816,DB00864,10038428,22,6847,35,8357,0.353059348,0.767207143,0.428332035,1.346462791,0.522808147,DB0086410038428_,0.648540713,-0.264998445,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,tacrolimus,DB00864
,229833,DB00697,10015150,56,6040,14,1792,0.668530476,1.18672768,0.650121185,2.314020797,0.798578634,DB0069710015150_,0.224921839,0.17119967,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,tizanidine,DB00697
,229836,DB05676,10015150,124,47005,88,25241,0.051235551,0.756687338,0.570895853,1.006461691,0.127356041,DB0567610015150_,2.06076864,-0.278805138,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,229856,DB00451,10037876,56,47215,12,15407,0.206358056,1.522760187,0.806549505,3.122130752,0.356885319,DB0045110037876_,1.030340785,0.4205246,NA,10037876,Rash papular,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,229857,DB00563,10037876,52,46594,12,15336,0.311608171,1.426244729,0.751093096,2.936447826,0.479025691,DB0056310037876_,0.736001048,0.355044926,NA,10037876,Rash papular,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,229951,DB00182,10051076,107,5087,57,2795,0.934297084,1.031401892,0.738431707,1.453497195,0.97479454,DB0018210051076_,0.025528558,0.030918937,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,amphetamine,DB00182
,229952,DB00182,10067482,43,5151,31,2821,0.271880756,0.759706352,0.466523695,1.250151616,0.434752203,DB0018210067482_,0.832979059,-0.274823299,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,229958,DB06273,10022095,57,5038,8,1402,0.069518866,1.982549255,0.938232235,4.824136697,0.160437543,DB0627310022095_,1.829850552,0.684383519,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,229964,DB00073,10067482,224,7182,107,6300,1.79042971368797e-07,1.836282324,1.448339109,2.340101225,3.07189588931386e-06,DB0007310067482_,12.69321563,0.607743052,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,229965,DB06273,10067482,249,4846,66,1344,0.779627641,1.046357216,0.788915938,1.403775806,0.880016857,DB0627310067482_,0.127814216,0.045314814,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,229979,DB09033,10033371,52,2572,22,1647,0.117892636,1.513433414,0.899233933,2.627373931,0.238031105,DB0903310033371_,1.43535392,0.414380854,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,vedolizumab,DB09033
,230024,DB01175,10061024,35,10689,24,4868,0.123650015,0.664170014,0.383518263,1.168460657,0.246587053,DB0117510061024_,1.400040192,-0.409217117,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,escitalopram,DB01175
,230229,DB00091,10020772,107,5403,54,2616,0.799470068,0.959398626,0.682950245,1.361302288,0.891654641,DB0009110020772_,0.114676396,-0.041448622,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,cyclosporine,DB00091
,230231,DB00091,10046735,56,5454,8,2662,0.000397946,3.416141537,1.616750679,8.31074711,0.002551535,DB0009110046735_,5.97105999,1.228511709,female,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,cyclosporine,DB00091
,230242,DB01050,10005734,43,18065,33,9338,0.090559971,0.673538471,0.417721572,1.095101385,0.196141138,DB0105010005734_,1.628920789,-0.395210164,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,ibuprofen,DB01050
,230267,DB01020,10011224,41,1772,36,1842,0.490870576,1.183823043,0.734239195,1.916237595,0.654087656,DB0102010011224_,0.424513906,0.168749068,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,isosorbide mononitrate,DB01020
,230285,DB00497,10038063,38,19229,33,16342,1,0.978624764,0.597300761,1.610906212,1,DB0049710038063_,0,-0.021606995,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,230330,DB05676,10028810,578,46551,276,25053,0.104456653,1.127080251,0.973957395,1.306673736,0.21768359,DB0567610028810_,1.524712692,0.11963044,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,apremilast,DB05676
,230360,DB08820,10011224,167,4234,126,3419,0.590311724,1.07028312,0.84029878,1.365890327,0.736890921,DB0882010011224_,0.305315402,0.067923211,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ivacaftor,DB08820
,230361,DB08820,10013573,44,4357,27,3518,0.282151824,1.315775974,0.795052555,2.214598619,0.446177397,DB0882010013573_,0.807038654,0.274426586,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ivacaftor,DB08820
,230370,DB08820,10037844,39,4362,16,3529,0.020667109,1.971832784,1.074657064,3.786538771,0.063417576,DB0882010037844_,2.758014224,0.678963458,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ivacaftor,DB08820
,230385,DB00230,10040047,112,19562,77,8574,0.003246559,0.637536439,0.472160099,0.864611689,0.014425798,DB0023010040047_,4.238737172,-0.450143845,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,pregabalin,DB00230
,230386,DB00273,10040047,43,8438,12,2181,0.866919701,0.926192471,0.478792886,1.93291767,0.94001833,DB0027310040047_,0.061855904,-0.076673214,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,topiramate,DB00273
,230391,DB00273,10047942,47,8434,10,2183,0.742020076,1.216493202,0.605388125,2.704601005,0.85212393,DB0027310047942_,0.160023304,0.195972295,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,topiramate,DB00273
,230491,DB01050,10001053,42,18066,30,9341,0.173476046,0.723847491,0.442103029,1.198620695,0.31549283,DB0105010001053_,1.153619322,-0.323174557,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,230583,DB00338,10064848,714,32960,469,21803,0.928254576,1.00705786,0.893895007,1.135360502,0.970145986,DB0033810064848_,0.030308718,0.00703307,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,230646,DB00996,10052251,35,38918,17,22408,0.666099346,1.18538696,0.646375206,2.256808389,0.796887775,DB0099610052251_,0.227041419,0.17006927,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,230891,DB00706,10020100,8,1067,72,15853,0.166334477,1.650767029,0.684755837,3.441766771,0.305907665,DB0070610020100_,1.184471972,0.501240046,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,tamsulosin,DB00706
,231127,DB00421,10064848,80,8823,45,5207,0.852684669,1.049177343,0.718028536,1.549737645,0.927913245,DB0042110064848_,0.074817036,0.048006374,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,spironolactone,DB00421
,231134,DB00112,10069339,58,5875,75,4016,0.000344945,0.528679637,0.367739863,0.756725249,0.002267855,DB0011210069339_,6.088920893,-0.637372631,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,bevacizumab,DB00112
,231137,DB01590,10069339,31,4707,64,2803,5.64735540635938e-09,0.288492108,0.181054833,0.450914022,1.34032268041676e-07,DB0159010069339_,15.82518526,-1.243087548,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,everolimus,DB01590
,231182,DB08931,10037087,117,6460,27,2419,0.023089011,1.622628311,1.057234134,2.572688268,0.069126333,DB0893110037087_,2.671819529,0.484047249,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,riociguat,DB08931
,231186,DB08931,10041349,119,6458,34,2412,0.198778241,1.307155208,0.883505122,1.980193448,0.347572664,DB0893110041349_,1.056781531,0.267853179,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,231198,DB08931,10064687,84,6493,17,2429,0.017997603,1.848398688,1.085823578,3.328656624,0.056852181,DB0893110064687_,2.867300703,0.61431969,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,riociguat,DB08931
,231203,DB00437,10003285,27,6894,38,11508,0.522094201,1.186045289,0.695740014,1.996164557,0.680767224,DB0043710003285_,0.384534847,0.170624487,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,allopurinol,DB00437
,231207,DB01098,10003285,37,8112,14,7195,0.00697513,2.343888888,1.236493198,4.697461818,0.026712506,DB0109810003285_,3.622623436,0.851811468,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,231210,DB14500,10003285,45,7764,18,4055,0.424573109,1.305708398,0.739744125,2.399895432,0.593359431,DB1450010003285_,0.521954941,0.266745727,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,231212,DB00437,10076309,44,6877,77,11469,0.850814287,0.952989107,0.641717626,1.399800986,0.926372712,DB0043710076309_,0.076478629,-0.048151805,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,allopurinol,DB00437
,231215,DB00877,10076309,58,1050,75,1356,1,0.998705264,0.689550429,1.440387606,1,DB0087710076309_,0,-0.001295575,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sirolimus,DB00877
,231219,DB14500,10076309,52,7757,30,4043,0.642602745,0.903435613,0.564692377,1.469313088,0.779042647,DB1450010076309_,0.249689489,-0.101550435,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium,DB14500
,231227,DB00958,10015090,52,4542,25,2560,0.552585322,1.172351204,0.712464774,1.97666072,0.706385817,DB0095810015090_,0.347593707,0.159011308,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carboplatin,DB00958
,231236,DB00958,10039906,34,4560,18,2567,0.885666308,1.063324696,0.582558527,2.004076637,0.952411128,DB0095810039906_,0.04875848,0.061400505,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,carboplatin,DB00958
,231255,DB01276,10000081,46,1971,35,1476,1,0.984214685,0.61688409,1.582599155,1,DB0127610000081_,0,-0.01591123,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,exenatide,DB01276
,231314,DB00060,10005169,55,9453,10,2455,0.357235818,1.428333865,0.719733785,3.14751802,0.526932855,DB0006010005169_,0.640682149,0.356508636,NA,10005169,Blindness,10015919,Eye disorders,Eye,interferon beta-1a,DB00060
,231320,DB00230,10008469,77,19597,20,8631,0.035540007,1.695606237,1.025311736,2.930446825,0.0965799,DB0023010008469_,2.337384632,0.528040339,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,231348,DB00181,10033557,57,9799,11,5860,0.000212546,3.098638457,1.606683837,6.558171566,0.001515262,DB0018110033557_,6.492167077,1.130962808,female,10033557,Palpitations,10007541,Cardiac disorders,Card,baclofen,DB00181
,231387,DB00184,10033371,31,1263,22,960,0.88873769,1.071027649,0.596152206,1.954765916,0.953896257,DB0018410033371_,0.047200359,0.068618607,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,nicotine,DB00184
,231388,DB00199,10033371,51,2659,9,691,0.335500391,1.47244448,0.713429893,3.419395695,0.50470973,DB0019910033371_,0.683771807,0.386923931,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,erythromycin,DB00199
,231553,DB00338,10061481,222,33452,143,22129,0.830223368,1.026968596,0.827977952,1.277078296,0.910937603,DB0033810061481_,0.093280877,0.026611352,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,231585,DB00316,10030995,42,65432,17,36936,0.279262976,1.39462884,0.776954468,2.613508125,0.443117028,DB0031610030995_,0.813921372,0.332628315,NA,10030995,Oral mucosal blistering,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,231588,DB00451,10030995,45,47226,15,15404,1,0.978528222,0.535204226,1.890450897,1,DB0045110030995_,0,-0.02170565,NA,10030995,Oral mucosal blistering,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,231621,DB00996,10049040,37,38916,20,22405,0.891058076,1.065100004,0.602211826,1.937303086,0.954769945,DB0099610049040_,0.046284862,0.063068695,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,231695,DB13961,10038435,50,9407,51,6363,0.041895575,0.663182372,0.439222192,1.000807413,0.109498377,DB1396110038435_,2.21184555,-0.410705255,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,fish oil,DB13961
,231728,DB01240,10003053,64,5687,7,1569,0.013366429,2.522268758,1.152983085,6.53836527,0.044867806,DB0124010003053_,3.104034766,0.925158797,NA,10003053,Application site pruritus,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,231745,DB00682,10037324,55,19404,10,16354,2.96901413319782e-07,4.635257331,2.339126787,10.20421387,4.85025086955281e-06,DB0068210037324_,12.23648013,1.533691716,female,10037324,Pulmonary arterial pressure increased,10022891,Investigations,Inv,warfarin,DB00682
,231750,DB00203,10052271,50,13828,16,8922,0.015739235,2.016227339,1.128377571,3.795659523,0.051191709,DB0020310052271_,2.972177702,0.701228111,NA,10052271,Catheter site rash,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,231752,DB01240,10052271,136,5615,28,1548,0.178677832,1.339006885,0.882495669,2.097949475,0.322222004,DB0124010052271_,1.132514516,0.291928208,NA,10052271,Catheter site rash,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,231822,DB00924,10003246,70,10092,15,4236,0.016555954,1.958701026,1.108850371,3.688663709,0.053232203,DB0092410003246_,2.933091742,0.672281512,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,231825,DB11089,10003246,50,10125,17,8390,0.001215797,2.437009393,1.38052002,4.510870614,0.006468417,DB1108910003246_,5.040823938,0.890771629,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,231846,DB01268,10028372,23,2120,31,3099,0.781930463,1.084538041,0.602063621,1.927379313,0.881222599,DB0126810028372_,0.126445019,0.081154128,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,sunitinib,DB01268
,232031,DB01068,10068319,84,13679,14,6826,3.34776497233152e-05,2.993949385,1.687439979,5.714576914,0.000312486,DB0106810068319_,8.070951518,1.096593381,female,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,232036,DB01068,10073085,34,13729,19,6821,0.664038635,0.889076919,0.492511579,1.651198215,0.795412926,DB0106810073085_,0.228893896,-0.117571524,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,232040,DB06285,10019303,98,8752,7,1099,0.161589378,1.757916469,0.818869446,4.498397385,0.299585616,DB0628510019303_,1.205355038,0.564129283,NA,10019303,Heart rate increased,10022891,Investigations,Inv,teriparatide,DB06285
,232130,DB05351,10013709,170,2553,62,1069,0.413297713,1.148063356,0.845527697,1.575452025,0.58271364,DB0535110013709_,0.540059397,0.138076485,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dexlansoprazole,DB05351
,232133,DB05351,10016322,45,2678,15,1116,0.567670572,1.250095892,0.680570372,2.424860083,0.718765914,DB0535110016322_,0.330219546,0.223220262,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,dexlansoprazole,DB05351
,232154,DB13867,10007559,39,4511,24,2530,0.792156171,0.911397206,0.533083862,1.58823455,0.88743507,DB1386710007559_,0.119419921,-0.092776466,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,fluticasone,DB13867
,232176,DB00338,10014625,89,33585,71,22201,0.257571187,0.828635207,0.599500267,1.148929586,0.418443663,DB0033810014625_,0.871213015,-0.18797526,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,232184,DB00497,10020919,39,19228,39,16336,0.496256344,0.849599995,0.530612196,1.360349371,0.658534089,DB0049710020919_,0.417738992,-0.162989634,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,232200,DB13867,10030124,76,4474,29,2525,0.081379451,1.478966759,0.949640482,2.360352501,0.180686647,DB1386710030124_,1.710990979,0.391343708,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,232217,DB13867,10037400,38,4512,15,2539,0.314329815,1.425494038,0.76425519,2.795366732,0.481939863,DB1386710037400_,0.729935939,0.354518447,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,232230,DB13867,10038435,39,4511,26,2528,0.517216419,0.84064119,0.497604097,1.441892348,0.676847247,DB1386710038435_,0.390309664,-0.173590357,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,fluticasone,DB13867
,232252,DB00497,10040979,49,19218,26,16349,0.062789647,1.603241505,0.97663035,2.688959009,0.148660229,DB0049710040979_,1.90609192,0.47202752,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,232258,DB00421,10054236,52,8851,16,5236,0.022870506,1.922525198,1.079172974,3.611609733,0.068585426,DB0042110054236_,2.679675217,0.653639529,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,spironolactone,DB00421
,232271,DB00761,10058080,56,15251,29,8596,0.821062734,1.088404557,0.682690786,1.769276565,0.904700649,DB0076110058080_,0.100151165,0.084712915,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,232343,DB00482,10049848,38,8221,18,3053,0.450725345,0.784000638,0.435811213,1.461725127,0.618400444,DB0048210049848_,0.480619064,-0.243345445,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,232398,DB06724,10043607,61,7868,32,3887,0.824992724,0.94174355,0.603140447,1.495809602,0.907376353,DB0672410043607_,0.097197973,-0.060022281,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,calcium carbonate,DB06724
,232450,DB00927,10039906,68,7429,42,4974,0.697427834,1.084022494,0.725892678,1.635519086,0.818059289,DB0092710039906_,0.200820464,0.080678654,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,232460,DB08932,10067671,76,19367,37,6560,0.082117989,0.695760968,0.463301176,1.061486621,0.181865555,DB0893210067671_,1.704487572,-0.362749114,NA,10067671,Disease complication,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,232470,DB00334,10010144,278,2571,213,2599,0.003931863,1.319308318,1.090338591,1.598049502,0.016840317,DB0033410010144_,4.083979466,0.277107598,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,olanzapine,DB00334
,232513,DB08931,10019196,53,6524,24,2422,0.440070661,0.819822639,0.496047171,1.391961718,0.608354756,DB0893110019196_,0.496997087,-0.198667256,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,riociguat,DB08931
,232564,DB00404,10043417,62,19830,25,9837,0.425671811,1.230206829,0.761351011,2.04442575,0.594405054,DB0040410043417_,0.520194282,0.207182309,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,232627,DB00921,10003239,44,5801,21,4882,0.033525391,1.763214704,1.024630999,3.126589234,0.092400662,DB0092110003239_,2.381621137,0.56713868,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,buprenorphine,DB00921
,232652,DB00818,10002198,50,1370,31,1646,0.004490493,1.937400471,1.205960731,3.156642351,0.018744263,DB0081810002198_,3.976867571,0.661347111,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,propofol,DB00818
,232763,DB00635,10047482,41,33012,16,23778,0.043021992,1.845699425,1.013251812,3.524282928,0.111725838,DB0063510047482_,2.191707284,0.612858298,NA,10047482,Viral upper respiratory tract infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,232970,DB00472,10048010,57,10702,16,4296,0.242796993,1.429968405,0.80881327,2.671247806,0.401038046,DB0047210048010_,0.913698978,0.35765235,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,233041,DB00590,10069339,17,759,75,1877,0.033834381,0.560648967,0.308223371,0.966269512,0.093039237,DB0059010069339_,2.374733977,-0.578660296,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,doxazosin,DB00590
,233108,DB00476,10039101,64,17193,10,6167,0.011455129,2.295654789,1.169834093,5.018452639,0.0396939,DB0047610039101_,3.226557756,0.831018114,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,233116,DB00381,10052140,37,29323,16,22871,0.052089045,1.803644058,0.978659387,3.473514467,0.128958354,DB0038110052140_,2.048265766,0.589809095,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,amlodipine,DB00381
,233157,DB00433,10010264,56,7600,21,5999,0.00269485,2.104776652,1.252783251,3.664098212,0.012386838,DB0043310010264_,4.391120844,0.744209358,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,233159,DB00654,10010264,49,3767,22,2576,0.11406775,1.522986624,0.901050995,2.652151059,0.23226205,DB0065410010264_,1.459889019,0.420673291,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,233162,DB01377,10010264,75,3721,33,2637,0.023281968,1.610521471,1.052459597,2.512453709,0.069545602,DB0137710010264_,2.665772593,0.476558022,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,magnesium oxide,DB01377
,233198,DB01377,10013971,41,3755,17,2653,0.080695274,1.703834591,0.944464712,3.206049743,0.179508741,DB0137710013971_,1.717531373,0.532881353,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium oxide,DB01377
,233208,DB06724,10016322,122,7807,34,3885,0.002590792,1.785536113,1.209594313,2.69958961,0.011997702,DB0672410016322_,4.423040107,0.579718713,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,233232,DB00624,10037087,11,551,49,4347,0.098246919,1.770810584,0.825246727,3.477509859,0.208251301,DB0062410037087_,1.569009749,0.571437399,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,testosterone,DB00624
,233256,DB00480,10031009,120,67308,54,67608,4.20057628004496e-07,2.232122906,1.605770759,3.138034018,6.61150583957974e-06,DB0048010031009_,11.92669912,0.802953108,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,233294,DB00502,10029282,68,1326,112,1760,0.187654013,0.805913799,0.582182311,1.108933321,0.33365932,DB0050210029282_,1.097634805,-0.215778492,NA,10029282,Neuroleptic malignant syndrome,10029205,Nervous system disorders,Nerv,haloperidol,DB00502
,233308,DB00316,10029883,64,65410,38,36915,0.836738762,0.950509414,0.626431536,1.460028271,0.915684947,DB0031610029883_,0.088082918,-0.050757213,NA,10029883,Obesity,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,233359,DB00989,10011906,31,803,96,782,9.81787088649968e-09,0.31466855,0.200344615,0.482576696,2.21608189138381e-07,DB0098910011906_,15.32235493,-1.156235415,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,rivastigmine,DB00989
,233366,DB00316,10027496,15,65459,40,36913,4.52699947073535e-08,0.211471557,0.108534933,0.39133343,8.82076953953141e-07,DB0031610027496_,13.94098654,-1.553664771,male,10027496,Methaemoglobinaemia,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,233403,DB00787,10024384,41,16959,53,17195,0.256963566,0.784357417,0.508407121,1.202429636,0.417859007,DB0078710024384_,0.872611208,-0.242890474,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,acyclovir,DB00787
,233445,DB00333,10070863,433,2638,486,2666,0.143106459,0.900418767,0.780500543,1.038534298,0.274195669,DB0033310070863_,1.293913308,-0.104895327,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,methadone,DB00333
,233455,DB00091,10069339,54,5456,75,2595,3.20258307186026e-09,0.342498032,0.236034027,0.494112599,8.04010468422606e-08,DB0009110069339_,16.33623864,-1.071489367,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,cyclosporine,DB00091
,233514,DB00921,10066169,58,5787,53,4850,0.701856738,0.917157838,0.619686189,1.359933513,0.8210376,DB0092110066169_,0.197186372,-0.086475697,NA,10066169,Substance abuse,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,233545,DB00787,10019974,123,16877,71,17177,0.000125709,1.763148226,1.304901051,2.397917136,0.000970414,DB0078710019974_,6.937787727,0.567100976,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,acyclovir,DB00787
,233553,DB08895,10015090,91,28023,16,6630,0.324567206,1.345598599,0.784990594,2.454972782,0.493050281,DB0889510015090_,0.70714412,0.296838969,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,233564,DB00760,10059866,26,754,48,967,0.151776979,0.694822079,0.40969673,1.154797637,0.286407797,DB0076010059866_,1.25033862,-0.364099468,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,meropenem,DB00760
,233586,DB00425,10019974,48,12647,23,7461,0.461387669,1.231208791,0.73369854,2.122461665,0.628664915,DB0042510019974_,0.46415689,0.207996444,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,zolpidem,DB00425
,233588,DB00706,10019974,8,1067,59,15866,0.072263519,2.01612765,0.829721324,4.252104605,0.16522674,DB0070610019974_,1.800436566,0.701178667,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,tamsulosin,DB00706
,233626,DB09037,10010774,50,2476,35,2800,0.036855825,1.615347913,1.02422704,2.572935382,0.099283153,DB0903710010774_,2.30977938,0.479550359,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,pembrolizumab,DB09037
,233640,DB06228,10071229,19,15893,34,16042,0.053407477,0.564075808,0.303804424,1.017862282,0.131381893,DB0622810071229_,2.029646981,-0.572566625,NA,10071229,Procedural haemorrhage,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,233805,DB08895,10009900,48,28066,24,6622,0.003951056,0.471891368,0.283193766,0.806100098,0.016905991,DB0889510009900_,4.080087197,-0.751006472,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,233826,DB00722,10047943,67,25336,42,25990,0.012494651,1.636389571,1.095903732,2.468292889,0.042522419,DB0072210047943_,3.157723825,0.492492334,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,lisinopril,DB00722
,233897,DB00425,10040979,29,12666,36,7448,0.002903841,0.473701798,0.27992074,0.795314855,0.013154237,DB0042510040979_,4.331011388,-0.747177273,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,233898,DB01050,10040979,39,18069,17,9354,0.672315133,1.187596217,0.655872686,2.240171202,0.801042712,DB0105010040979_,0.22184101,0.171931278,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,233910,DB01050,10057668,58,18050,37,9334,0.330009196,0.810641219,0.527188855,1.260560545,0.498651473,DB0105010057668_,0.695847878,-0.209929717,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,233922,DB00193,10003983,43,19277,12,8690,0.14739106,1.615328275,0.836273575,3.366918854,0.280310687,DB0019310003983_,1.271856694,0.479538202,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,233941,DB00425,10042609,51,12644,8,7476,0.000112577,3.769138559,1.774292308,9.201509605,0.000883049,DB0042510042609_,7.032129336,1.326846476,female,10042609,Surgery,10042613,Surgical and medical procedures,Surg,zolpidem,DB00425
,233945,DB01156,10042609,64,13558,13,6315,0.004483645,2.292974289,1.249306717,4.541712389,0.018723107,DB0115610042609_,3.977996828,0.829849791,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,bupropion,DB01156
,233993,DB00230,10012680,51,19623,33,8618,0.096023912,0.67873916,0.429296199,1.086551962,0.204827634,DB0023010012680_,1.585586463,-0.387518379,NA,10012680,Diabetic neuropathy,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,234147,DB00374,10052915,76,17640,20,5704,0.475641209,1.228736565,0.742121337,2.125684207,0.641205723,DB0037410052915_,0.444404933,0.205986459,NA,10052915,Catheter placement,10042613,Surgical and medical procedures,Surg,treprostinil,DB00374
,234163,DB01240,10069802,43,5708,20,1556,0.062801834,0.586139529,0.336257961,1.055045361,0.148663029,DB0124010069802_,1.906073087,-0.534197414,NA,10069802,Device related sepsis,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,234181,DB01068,10005724,49,13714,11,6829,0.013250331,2.218103989,1.136944474,4.734196083,0.044540564,DB0106810005724_,3.11135496,0.796652772,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,clonazepam,DB01068
,234190,DB01240,10065066,52,5699,18,1558,0.381933318,0.789795455,0.452898512,1.438911274,0.55207002,DB0124010065066_,0.594080393,-0.235981285,NA,10065066,Device connection issue,10077536,Product issues,Prod,epoprostenol,DB01240
,234294,DB00153,10016766,46,7377,7,3432,0.002796217,3.056961988,1.368956318,8.034787,0.012759324,DB0015310016766_,4.361492997,1.117421608,female,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,ergocalciferol,DB00153
,234314,DB00588,10043882,57,16467,19,8449,0.114611467,1.539235563,0.901392232,2.741933258,0.233044202,DB0058810043882_,1.456527133,0.431285905,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,fluticasone propionate,DB00588
,234338,DB00254,10062355,43,5892,21,3367,0.603806076,1.170128118,0.677983128,2.079450987,0.747337482,DB0025410062355_,0.291238412,0.157113246,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,234366,DB00641,10020100,70,14054,33,12442,0.002829627,1.87785915,1.223701909,2.935286271,0.012884668,DB0064110020100_,4.351717232,0.630132378,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,234368,DB00787,10020100,71,16929,55,17193,0.153007102,1.31102566,0.908371538,1.900800471,0.288186856,DB0078710020100_,1.244146203,0.270809777,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,234372,DB01234,10020100,126,31499,89,32799,0.005041215,1.474141463,1.114374288,1.957082498,0.020598219,DB0123410020100_,3.882550658,0.388075761,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,234416,DB01076,10016750,32,25715,24,25559,0.349556396,1.325233298,0.75619505,2.352117699,0.519174452,DB0107610016750_,0.655515322,0.281588518,NA,10016750,Flank pain,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,234440,DB08895,10039906,44,28070,12,6634,0.612661827,0.866546539,0.449587445,1.803442223,0.754524486,DB0889510039906_,0.281667548,-0.143239462,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,234461,DB00950,10016322,92,4626,24,2032,0.024580702,1.683700213,1.061067691,2.768638018,0.072575541,DB0095010016322_,2.623127311,0.520993879,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,234471,DB00950,10020937,54,4664,18,2038,0.368083056,1.310800535,0.754546951,2.381191471,0.53781375,DB0095010020937_,0.620242969,0.270638046,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,fexofenadine,DB00950
,234585,DB00683,10033295,26,1558,42,1596,0.085452668,0.634237945,0.371392533,1.064745291,0.187450313,DB0068310033295_,1.674241464,-0.455331087,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,midazolam,DB00683
,234598,DB00091,10016173,123,5387,28,2642,0.000146052,2.154258781,1.415476352,3.382999016,0.001101575,DB0009110016173_,6.811014072,0.767446711,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclosporine,DB00091
,234611,DB00193,10024774,52,19268,22,8680,0.900080111,1.064786435,0.634964801,1.842289147,0.95659897,DB0019310024774_,0.044371025,0.062774248,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,tramadol,DB00193
,234677,DB00916,10039906,35,5288,19,2412,0.557247689,0.840268565,0.466578051,1.558403972,0.710440952,DB0091610039906_,0.341869442,-0.174033718,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,metronidazole,DB00916
,234679,DB00916,10044565,32,5291,19,2412,0.36594238,0.767778418,0.421188622,1.436804568,0.535503973,DB0091610044565_,0.624546971,-0.264254106,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,metronidazole,DB00916
,234710,DB00727,10055798,48,3795,30,4143,0.01672061,1.746583085,1.081831401,2.861353843,0.053676263,DB0072710055798_,2.924784398,0.557661357,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,nitroglycerin,DB00727
,234713,DB06724,10055798,37,7892,15,3904,0.558201727,1.220159556,0.652766639,2.396180465,0.711196161,DB0672410055798_,0.340806993,0.198981634,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,calcium carbonate,DB06724
,234829,DB00586,10069339,84,7025,55,2750,0.004254876,0.597898945,0.419298163,0.858531408,0.017967615,DB0058610069339_,4.019184333,-0.514333527,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,diclofenac,DB00586
,234840,DB00515,10040047,54,1816,78,2073,0.21417176,0.790329888,0.544734284,1.139511172,0.366492283,DB0051510040047_,1.003777814,-0.235304841,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,cisplatin,DB00515
,234858,DB00864,10005750,30,6839,45,8347,0.416598407,0.813678178,0.494355019,1.321887462,0.585827579,DB0086410005750_,0.534729766,-0.20619035,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,tacrolimus,DB00864
,234879,DB00787,10028836,59,16941,23,17225,5.35480593655694e-05,2.608261113,1.585474776,4.427509734,0.000467922,DB0078710028836_,7.667207973,0.958683759,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,234917,DB01234,10015929,56,31569,15,32873,2.98481498622699e-07,3.887095219,2.168057909,7.402618672,4.86849903276305e-06,DB0123410015929_,12.23272488,1.357662148,female,10015929,Eye infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,234966,DB00338,10033433,120,33554,45,22227,0.001030556,1.766445408,1.243713454,2.548053757,0.005646898,DB0033810033433_,5.176648842,0.568969283,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,234975,DB01075,10033433,49,19899,11,11086,0.0043238,2.481622074,1.272443443,5.294581487,0.018198731,DB0107510033433_,4.006403387,0.908912409,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,diphenhydramine,DB01075
,235032,DB00231,10040753,52,3244,11,2128,0.000231014,3.100437183,1.593613891,6.604214807,0.001625319,DB0023110040753_,6.422051319,1.131543128,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,temazepam,DB00231
,235111,DB00787,10029223,36,16964,35,17213,0.90569137,1.043681557,0.636585407,1.712633883,0.957861963,DB0078710029223_,0.0430516,0.042754421,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,235120,DB08910,10039906,28,16716,46,17442,0.062468348,0.635143486,0.382086556,1.038468666,0.148046211,DB0891010039906_,1.91023082,-0.453904343,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,235140,DB08910,10019303,53,16691,62,17426,0.57572402,0.892485675,0.606238189,1.309794812,0.725172794,DB0891010019303_,0.321345315,-0.113744816,NA,10019303,Heart rate increased,10022891,Investigations,Inv,pomalidomide,DB08910
,235144,DB00804,10000081,111,2889,40,859,0.324236114,0.825130682,0.56500384,1.22604058,0.492666845,DB0080410000081_,0.707922105,-0.192213503,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,dicyclomine,DB00804
,235227,DB00956,10020751,55,5759,8,3459,1.9184866093903e-05,4.128815149,1.952278581,10.05040686,0.000192545,DB0095610020751_,8.555182945,1.417990477,female,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,hydrocodone,DB00956
,235236,DB00956,10047571,39,5775,16,3451,0.26306316,1.456534683,0.793975557,2.796315174,0.424868498,DB0095610047571_,0.855975575,0.37606011,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,hydrocodone,DB00956
,235250,DB00213,10061623,112,18783,102,13319,0.07052519,0.778632082,0.5895037,1.029400933,0.162225835,DB0021310061623_,1.818765873,-0.25021664,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,235262,DB00514,10003549,43,2123,30,1506,1,1.016765045,0.620024997,1.687047181,1,DB0051410003549_,0,0.016626062,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,dextromethorphan,DB00514
,235268,DB00972,10003549,42,2462,30,1149,0.096285104,0.653443081,0.397086272,1.087264962,0.205160015,DB0097210003549_,1.583965043,-0.425499848,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,azelastine,DB00972
,235278,DB00404,10003553,114,19778,14,9848,7.7769560357075e-09,4.054030418,2.318528509,7.655481181,1.78999377757068e-07,DB0040410003553_,15.53588351,1.399711551,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,235309,DB00836,10008469,37,5498,18,4057,0.17132085,1.516739126,0.840515955,2.834384179,0.312654902,DB0083610008469_,1.162655247,0.416562719,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,235343,DB01225,10009033,36,5008,20,4620,0.08058937,1.660451523,0.934263143,3.032020027,0.179371827,DB0122510009033_,1.718294384,0.507089567,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,enoxaparin,DB01225
,235350,DB00852,10016256,86,1080,35,436,1,0.991962495,0.650938691,1.539082164,1,DB0085210016256_,0,-0.00806998,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pseudoephedrine,DB00852
,235367,DB00448,10020642,35,5110,17,3107,0.477089259,1.251748729,0.681380492,2.387014181,0.64248232,DB0044810020642_,0.44241598,0.224541557,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,lansoprazole,DB00448
,235378,DB00959,10020642,62,8016,47,4955,0.322389021,0.815438611,0.548200385,1.219935975,0.490719832,DB0095910020642_,0.711881921,-0.204029137,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,methylprednisolone,DB00959
,235396,DB00972,10037660,49,2455,27,1152,0.534913305,0.851645018,0.518941706,1.42478493,0.691445387,DB0097210037660_,0.368971109,-0.160585485,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,azelastine,DB00972
,235416,DB00836,10042464,63,5472,38,4037,0.362907778,1.223095801,0.803264781,1.884555155,0.532418803,DB0083610042464_,0.630324877,0.201385186,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,loperamide,DB00836
,235473,DB00904,10058267,34,23035,17,14439,0.475483418,1.253624195,0.680914831,2.393739364,0.641091646,DB0090410058267_,0.444582859,0.226038712,NA,10058267,Troponin increased,10022891,Investigations,Inv,ondansetron,DB00904
,235476,DB01076,10058267,21,25726,37,25546,0.035701691,0.563606157,0.313340779,0.988655305,0.096881893,DB0107610058267_,2.334262644,-0.573399574,NA,10058267,Troponin increased,10022891,Investigations,Inv,atorvastatin,DB01076
,235651,DB11089,10020583,30,10145,23,8384,0.890280664,1.077954512,0.604893802,1.944846569,0.954589293,DB1108910020583_,0.04647409,0.075065275,NA,10020583,Hypercalcaemia,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,235655,DB00653,10069339,41,1051,50,772,0.022257746,0.602497635,0.384405644,0.939673809,0.067217791,DB0065310069339_,2.699817321,-0.506671539,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,magnesium sulfate,DB00653
,235663,DB00921,10035664,36,5809,27,4876,0.704677767,1.1191473,0.659716008,1.919685755,0.822904333,DB0092110035664_,0.194915327,0.112567056,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,buprenorphine,DB00921
,235743,DB00537,10011781,67,7490,20,4278,0.009756616,1.913295422,1.144824438,3.334004849,0.03489864,DB0053710011781_,3.355307423,0.648827107,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,235747,DB08910,10011781,70,16674,21,17467,6.98489009171316e-08,3.492045107,2.117326099,5.991141731,1.30767689501909e-06,DB0891010011781_,13.54725836,1.250487555,female,10011781,Cystitis,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,235752,DB00153,10017413,33,7390,30,3409,0.009260787,0.507445078,0.299513228,0.862927864,0.033478173,DB0015310017413_,3.396861602,-0.678366795,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,ergocalciferol,DB00153
,235753,DB00264,10017413,189,29418,145,24747,0.409274447,1.096447795,0.877856577,1.371925484,0.578670765,DB0026410017413_,0.547021591,0.092075677,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,metoprolol,DB00264
,235766,DB00682,10017533,36,19423,15,16349,0.023616675,2.020087468,1.078268631,3.97289737,0.07032961,DB0068210017533_,2.65456238,0.703140812,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,warfarin,DB00682
,235770,DB08910,10017533,36,16708,17,17471,0.005805834,2.214313752,1.211435452,4.205965657,0.023061025,DB0891010017533_,3.769611312,0.794942537,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,235801,DB08910,10061394,35,16709,30,17458,0.45760155,1.218954382,0.726668691,2.05637166,0.624945745,DB0891010061394_,0.470090441,0.197993427,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pomalidomide,DB08910
,235832,DB00760,10037844,28,752,33,982,0.695727562,1.107930071,0.638877131,1.909303669,0.816830399,DB0076010037844_,0.202323795,0.102493474,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,meropenem,DB00760
,235843,DB00480,10060946,30,67398,34,67628,0.70794131,0.885365289,0.523338729,1.490903167,0.825491852,DB0048010060946_,0.191775886,-0.121754963,NA,10060946,Pneumonia bacterial,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,235862,DB01075,10000381,48,19900,79,11018,2.00348641522544e-09,0.336418266,0.22981478,0.487997652,5.23735857028351e-08,DB0107510000381_,16.76486346,-1.089400053,male,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,235885,DB01195,10013573,43,1196,25,719,1,1.033998281,0.611465878,1.782835491,1,DB0119510013573_,0,0.033433113,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,flecainide,DB01195
,235893,DB01195,10014380,49,1190,31,713,0.814588635,0.947086783,0.585740214,1.55191719,0.900568328,DB0119510014380_,0.10472924,-0.05436455,NA,10014380,Electrocardiogram QRS complex prolonged,10022891,Investigations,Inv,flecainide,DB01195
,235896,DB01195,10016256,56,1183,34,710,1,0.988516464,0.627248971,1.578033457,1,DB0119510016256_,0,-0.011549981,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,flecainide,DB01195
,235907,DB00557,10027175,66,5921,12,3055,0.000410922,2.837513017,1.51769111,5.776509181,0.002620667,DB0055710027175_,5.944326353,1.04292797,female,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,235912,DB01195,10028813,39,1200,19,725,0.493406383,1.239972606,0.693329354,2.290256198,0.656109302,DB0119510028813_,0.421427884,0.215089288,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,flecainide,DB01195
,235994,DB01409,10047942,31,6000,27,3939,0.284816313,0.753793413,0.434581014,1.314868318,0.449360503,DB0140910047942_,0.79992981,-0.282636936,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,tiotropium,DB01409
,236001,DB01373,10056812,97,22623,26,7355,0.462009799,1.212903836,0.779279237,1.950476371,0.629185721,DB0137310056812_,0.463328802,0.193017349,NA,10056812,Body height decreased,10022891,Investigations,Inv,calcium,DB01373
,236032,DB04854,10037087,28,753,32,1454,0.053226962,1.689222219,0.971944052,2.920393147,0.131074194,DB0485410037087_,2.031991747,0.524268198,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,febuxostat,DB04854
,236105,DB01222,10042674,66,9208,22,5383,0.020086276,1.753738201,1.066826861,2.988501207,0.061973728,DB0122210042674_,2.781044721,0.561749625,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,236118,DB00381,10031282,44,29316,13,22874,0.001214669,2.640772015,1.396560494,5.345048039,0.006463727,DB0038110031282_,5.04154926,0.971071304,NA,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,236146,DB01142,10037087,46,1694,15,769,0.327078116,1.391985275,0.757549102,2.701600571,0.495490074,DB0114210037087_,0.702207958,0.330730984,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,doxepin,DB01142
,236162,DB00158,10029366,38,16777,32,8072,0.021325101,0.57134767,0.347305642,0.945437143,0.065068232,DB0015810029366_,2.73231884,-0.559757376,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,folic acid,DB00158
,236306,DB00310,10012735,69,875,44,737,0.171929923,1.320644647,0.879780117,2.000030847,0.313342211,DB0031010012735_,1.160459361,0.278119986,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,chlorthalidone,DB00310
,236351,DB08932,10056819,92,19351,18,6579,0.028181916,1.737570153,1.039784838,3.06364089,0.080653457,DB0893210056819_,2.517593616,0.552487674,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,236391,DB00455,10039906,68,9333,43,5075,0.485198768,0.859930259,0.577517348,1.292804126,0.649294858,DB0045510039906_,0.431868338,-0.150903987,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,236394,DB01233,10039906,38,3383,25,1701,0.347072294,0.764336115,0.447806719,1.325805394,0.516511389,DB0123310039906_,0.660657941,-0.268747645,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,metoclopramide,DB01233
,236426,DB01076,10028641,49,25698,83,25500,0.002939263,0.585822536,0.402708479,0.844206113,0.013287216,DB0107610028641_,4.320952888,-0.534738375,NA,10028641,Myopathy,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,236435,DB09038,10003988,34,2214,31,2510,0.384803,1.243346047,0.738786373,2.099481886,0.554905877,DB0903810003988_,0.588956771,0.21780617,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,empagliflozin,DB09038
,236467,DB00930,10013709,41,1249,14,628,0.246668142,1.472216966,0.779146478,2.947018883,0.405723982,DB0093010013709_,0.902082197,0.386769405,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,colesevelam,DB00930
,236488,DB00768,10047513,37,1878,13,671,1,1.016915566,0.524437896,2.098310247,1,DB0076810047513_,0,0.016774091,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,olopatadine,DB00768
,236525,DB09079,10013968,67,590,85,792,0.79568652,1.058046362,0.742765781,1.502549793,0.889378303,DB0907910013968_,0.117232597,0.056424153,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nintedanib,DB09079
,236557,DB00153,10061818,49,7374,22,3417,1,1.032113788,0.611212399,1.795509915,1,DB0015310061818_,0,0.031608921,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,236609,DB00177,10061818,39,4761,28,2822,0.44836825,0.825621645,0.493972519,1.396407649,0.616113637,DB0017710061818_,0.484323857,-0.191618667,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,236624,DB00193,10023469,39,19281,12,8690,0.290144952,1.464788897,0.750930008,3.074487435,0.455311049,DB0019310023469_,0.786774469,0.381711135,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,tramadol,DB00193
,236641,DB00656,10040979,41,11972,17,6602,0.340418871,1.32995902,0.738395647,2.498748683,0.50963463,DB0065610040979_,0.674061222,0.28514813,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,236689,DB00531,10051792,35,7217,27,6489,0.610874555,1.165521493,0.684587446,2.004592272,0.75295839,DB0053110051792_,0.283745311,0.15316862,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclophosphamide,DB00531
,236693,DB00997,10051792,47,5284,20,3494,0.104199832,1.553842808,0.901156356,2.773448886,0.217337928,DB0099710051792_,1.526301863,0.440731094,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,doxorubicin,DB00997
,236695,DB00019,10069339,16,18996,38,9491,3.843157419644e-08,0.210389915,0.109474943,0.386641041,7.60100773328386e-07,DB0001910069339_,14.08981482,-1.558792733,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,pegfilgrastim,DB00019
,236701,DB00541,10001551,31,3103,64,4233,0.060254081,0.66080297,0.414770709,1.032814888,0.143920988,DB0054110001551_,1.938490825,-0.414299562,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,vincristine,DB00541
,236709,DB00541,10003481,22,3112,46,4251,0.109291189,0.653342214,0.373497604,1.11103254,0.224967219,DB0054110003481_,1.491800579,-0.425654223,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,vincristine,DB00541
,236731,DB01168,10061428,23,658,33,798,0.585880569,0.845354712,0.468934736,1.500429308,0.733199935,DB0116810061428_,0.310336852,-0.167998962,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,procarbazine,DB01168
,236762,DB00959,10074171,26,8052,32,4970,0.009724309,0.50152286,0.286707052,0.869768732,0.034806763,DB0095910074171_,3.357943563,-0.69010609,NA,10074171,Aspergillus infection,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,236771,DB00316,10053483,155,65319,46,36907,6.60108951001769e-05,1.903882716,1.361674569,2.707625834,0.000558088,DB0031610053483_,7.490993449,0.643895336,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,236772,DB01075,10053483,139,19809,39,11058,7.92029847184288e-05,1.989551712,1.384753244,2.918086483,0.00065354,DB0107510053483_,7.333107402,0.687909343,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,236807,DB00476,10039117,38,17219,13,6164,1,1.046362135,0.544800753,2.142264774,1,DB0047610039117_,0,0.045319515,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,236908,DB00451,10039117,116,47155,35,15384,0.776559548,1.081261592,0.734918906,1.627222205,0.878213089,DB0045110039117_,0.129866016,0.0781285,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,236919,DB00451,10041541,39,47232,17,15402,0.350846474,0.74809839,0.413263449,1.410736546,0.520561067,DB0045110041541_,0.652848074,-0.290220772,NA,10041541,Spinal compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,237025,DB14513,10033557,72,7105,10,3554,1.66426089863294e-05,3.601124643,1.846634894,7.836094822,0.000169818,DB1451310033557_,8.680783719,1.281246197,female,10033557,Palpitations,10007541,Cardiac disorders,Card,magnesium,DB14513
,237030,DB01175,10039101,52,10672,12,4880,0.030417365,1.981434187,1.042624948,4.082567327,0.085578855,DB0117510039101_,2.45831705,0.68382092,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,237036,DB14513,10039101,47,7130,15,3549,0.139050217,1.559575867,0.855392657,3.007233414,0.268498436,DB1451310039101_,1.314910192,0.444413904,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium,DB14513
,237067,DB01175,10049848,85,10639,39,4853,1,0.99417754,0.671724787,1.494521313,1,DB0117510049848_,0,-0.005839476,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,237117,DB15566,10053762,39,968,30,632,0.531036877,0.848849533,0.508005715,1.430834359,0.687912749,DB1556610053762_,0.374093268,-0.163873336,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisolone acetate,DB15566
,237133,DB00482,10037153,118,8141,39,3032,0.587596712,1.126843065,0.776473856,1.66692008,0.734643481,DB0048210037153_,0.308369957,0.119419975,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,celecoxib,DB00482
,237134,DB00482,10037162,78,8181,45,3026,0.024277721,0.641155479,0.437550489,0.949440374,0.071899035,DB0048210037162_,2.632492439,-0.444483294,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,237137,DB00482,10050584,56,8203,22,3049,0.79935534,0.946129339,0.567367028,1.630303336,0.891621265,DB0048210050584_,0.114713827,-0.055375997,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,celecoxib,DB00482
,237224,DB00915,10039906,43,1412,22,1029,0.203576848,1.424186096,0.827378333,2.516318055,0.353389079,DB0091510039906_,1.040185622,0.35360049,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,amantadine,DB00915
,237308,DB08895,10047461,120,27994,12,6634,0.002523375,2.369778842,1.306674623,4.716935995,0.011743435,DB0889510047461_,4.444460909,0.862796635,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,237419,DB08906,10047700,60,2133,19,1139,0.054805367,1.686042616,0.986498172,3.007322037,0.133996331,DB0890610047700_,2.009942857,0.522384136,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,fluticasone furoate,DB08906
,237484,DB01076,10031252,39,25708,55,25528,0.098943227,0.704134076,0.454650117,1.081172814,0.209263173,DB0107610031252_,1.564162616,-0.350786493,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,237492,DB01076,10039203,43,25704,52,25531,0.356646435,0.821362008,0.535119497,1.254909356,0.526329321,DB0107610039203_,0.641828177,-0.196791331,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,237696,DB14513,10037377,37,7140,33,3531,0.015332559,0.554486643,0.336749671,0.916634075,0.050178119,DB1451310037377_,2.992176217,-0.589712562,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium,DB14513
,237765,DB00788,10008469,41,9315,24,5037,0.794855824,0.923771953,0.544340094,1.600305207,0.88886159,DB0078810008469_,0.117813747,-0.079290042,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,237767,DB00950,10008469,66,4652,21,2035,0.240570027,1.374820105,0.827791276,2.372530665,0.398536738,DB0095010008469_,0.919955595,0.31832289,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,237770,DB06724,10008469,49,7880,16,3903,0.185534825,1.516820824,0.846621795,2.861404266,0.330876103,DB0672410008469_,1.106011286,0.416616581,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,calcium carbonate,DB06724
,237842,DB06724,10020937,123,7806,27,3892,5.01555844419183e-05,2.271223982,1.484829101,3.591153005,0.000443139,DB0672410020937_,7.7216263,0.820318885,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,237853,DB00950,10028411,59,4659,21,2035,0.464801481,1.227113899,0.732359182,2.132458082,0.631757386,DB0095010028411_,0.459249842,0.204664988,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,fexofenadine,DB00950
,237859,DB00193,10031009,52,19268,8,8694,0.001976825,2.932755396,1.382748028,7.152484153,0.009634867,DB0019310031009_,4.642366772,1.075942389,female,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,tramadol,DB00193
,237869,DB00999,10031009,78,21352,20,12219,0.000724592,2.231783223,1.350895396,3.854477525,0.004212763,DB0099910031009_,5.469636541,0.802800917,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,237872,DB06724,10031009,45,7884,8,3911,0.004925859,2.790185428,1.300081266,6.860329038,0.020233818,DB0672410031009_,3.900399907,1.026108055,female,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,237893,DB00343,10042128,37,8699,13,5082,0.141163083,1.662680131,0.862819604,3.411969467,0.271501235,DB0034310042128_,1.303788589,0.508430837,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,237900,DB00927,10042128,67,7430,13,5003,5.41340813335597e-06,3.470043318,1.895602914,6.861192608,6.3395603825022e-05,DB0092710042128_,9.666116039,1.244167077,female,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,237903,DB06724,10042128,65,7864,14,3905,0.003664125,2.305350287,1.278463337,4.454179577,0.015902178,DB0672410042128_,4.141299226,0.835232633,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,237949,DB00788,10050584,94,9262,21,5040,0.000109623,2.435629215,1.503187182,4.122344205,0.000862584,DB0078810050584_,7.055578123,0.890205128,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,238009,DB00316,10007697,90,65384,23,36930,0.00037603,2.210135574,1.385266521,3.662899056,0.002436272,DB0031610007697_,6.01728609,0.79305386,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,238083,DB01020,10003988,34,1779,23,1855,0.111481333,1.54122343,0.877838586,2.751938509,0.228267999,DB0102010003988_,1.477234906,0.432576536,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,isosorbide mononitrate,DB01020
,238093,DB00787,10006784,48,16952,28,17220,0.021194206,1.741348211,1.070091125,2.883921702,0.064743996,DB0078710006784_,2.737314314,0.554659647,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,238210,DB00804,10016322,46,2954,16,883,0.648136224,0.859448393,0.474771606,1.634720393,0.783168329,DB0080410016322_,0.244407627,-0.151464499,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,dicyclomine,DB00804
,238211,DB00874,10016322,55,3280,14,1962,0.003606978,2.349624139,1.284878021,4.587832064,0.015694326,DB0087410016322_,4.154456019,0.854255374,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,238213,DB13867,10016322,71,4479,26,2528,0.069568909,1.541190085,0.968062199,2.523853689,0.160531891,DB1386710016322_,1.82926266,0.4325549,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,238230,DB00736,10022000,81,10510,69,5484,0.003248028,0.612533066,0.438032172,0.858628079,0.014429059,DB0073610022000_,4.238511097,-0.490152353,NA,10022000,Influenza,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,238232,DB00874,10022000,58,3277,23,1953,0.105544005,1.50277663,0.909298415,2.561418602,0.21943636,DB0087410022000_,1.516693022,0.407314483,NA,10022000,Influenza,10021881,Infections and infestations,Infec,guaifenesin,DB00874
,238235,DB01175,10022000,102,10622,39,4853,0.363337779,1.194893534,0.817245395,1.778447766,0.532861533,DB0117510022000_,0.629493677,0.178057089,NA,10022000,Influenza,10021881,Infections and infestations,Infec,escitalopram,DB01175
,238245,DB00697,10028810,75,6021,18,1788,0.458557128,1.237299348,0.729873466,2.206029695,0.625960069,DB0069710028810_,0.468468697,0.212931059,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,tizanidine,DB00697
,238248,DB00804,10028810,51,2949,13,886,0.656632887,1.178602109,0.628277812,2.373488264,0.790021304,DB0080410028810_,0.235695367,0.164329083,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,dicyclomine,DB00804
,238252,DB01109,10028810,38,4374,22,4248,0.052957817,1.677409099,0.965282852,2.982981899,0.130569009,DB0110910028810_,2.035853386,0.5172504,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,heparin,DB01109
,238253,DB01175,10028810,131,10593,35,4857,0.004088176,1.716085468,1.172056272,2.572519133,0.017387978,DB0117510028810_,4.051976236,0.540045806,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,escitalopram,DB01175
,238277,DB00316,10041052,36,65438,16,36937,0.472658107,1.270056837,0.68693349,2.451549788,0.638658219,DB0031610041052_,0.448385836,0.239061653,NA,10041052,Sluggishness,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,238312,DB00316,10061603,34,65440,29,36924,0.114928383,0.661558186,0.391099133,1.125748799,0.233525439,DB0031610061603_,1.454464263,-0.413157338,NA,10061603,Respiratory syncytial virus infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,238316,DB00559,10061603,31,9628,28,3278,0.000260117,0.376977339,0.218434152,0.65335362,0.001794921,DB0055910061603_,6.322793996,-0.975570203,NA,10061603,Respiratory syncytial virus infection,10021881,Infections and infestations,Infec,bosentan,DB00559
,238391,DB00115,10012267,35,18390,24,10448,0.499125805,0.828545019,0.478705502,1.456757883,0.660983036,DB0011510012267_,0.414027104,-0.188084106,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,238397,DB00996,10012267,38,38915,22,22403,1,0.994373973,0.573131892,1.765486766,1,DB0099610012267_,0,-0.005641913,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,238466,DB00115,10040070,31,18394,34,10438,0.009310682,0.517394509,0.307348353,0.868136233,0.033612315,DB0011510040070_,3.392862759,-0.658949623,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,238468,DB00281,10040070,27,11431,32,5639,0.001203728,0.416248144,0.239658691,0.717965728,0.006419151,DB0028110040070_,5.048469488,-0.876473697,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,lidocaine,DB00281
,238557,DB00661,10020772,57,3471,27,1568,0.813405266,0.953689144,0.590774713,1.574787225,0.899775248,DB0066110020772_,0.105610271,-0.047417505,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,verapamil,DB00661
,238586,DB06700,10048010,88,2137,16,602,0.116353716,1.549120333,0.894520448,2.850329021,0.235669133,DB0670010048010_,1.445326435,0.437687243,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,desvenlafaxine,DB06700
,238608,DB00472,10042609,41,10718,17,4295,0.884997283,0.96646185,0.536377726,1.816488742,0.952079302,DB0047210042609_,0.049106947,-0.034113453,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,fluoxetine,DB00472
,238808,DB08880,10013968,78,3260,15,794,0.507683617,1.266432158,0.717989029,2.38337225,0.668342668,DB0888010013968_,0.402954261,0.236203623,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,teriflunomide,DB08880
,238824,DB06168,10010264,39,570,23,377,0.788899002,1.121417904,0.641437264,2.000741647,0.885632966,DB0616810010264_,0.121452674,0.11459387,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,canakinumab,DB06168
,238848,DB06605,10042682,54,14019,8,13025,5.54965527472645e-09,6.270999248,2.964545634,15.26319837,1.31951776477779e-07,DB0660510042682_,15.84082931,1.835935712,female,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,238973,DB00186,10061309,81,16820,40,9968,0.396321518,1.200105682,0.811230891,1.800860194,0.565971004,DB0018610061309_,0.569212431,0.182409622,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lorazepam,DB00186
,238975,DB00264,10061309,85,29522,48,24844,0.029104267,1.49021629,1.03361224,2.170445323,0.082724574,DB0026410061309_,2.49223858,0.39892127,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metoprolol,DB00264
,238978,DB00904,10061309,131,22938,75,14381,0.566100373,1.095086743,0.817627414,1.47574252,0.717539729,DB0090410061309_,0.331926962,0.090833577,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ondansetron,DB00904
,238979,DB00996,10061309,74,38879,30,22395,0.125838951,1.420836203,0.917725453,2.250874895,0.249833968,DB0099610061309_,1.38695871,0.351245574,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,gabapentin,DB00996
,238981,DB11089,10061309,35,10140,26,8381,0.701328548,1.112598125,0.650282848,1.926435081,0.820620587,DB1108910061309_,0.197694411,0.106697934,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,docusate,DB11089
,238989,DB08895,10043417,181,27933,52,6594,0.21040683,0.821692393,0.599847346,1.142615022,0.36168619,DB0889510043417_,1.016978323,-0.196389172,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,239004,DB01175,10033664,51,10673,11,4881,0.01959013,2.120225285,1.090009645,4.515283074,0.060815705,DB0117510033664_,2.799907221,0.751522349,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,239040,DB00059,10016256,17,810,37,1070,0.095433139,0.607090506,0.318132363,1.114752528,0.203914973,DB0005910016256_,1.590052169,-0.499077395,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pegaspargase,DB00059
,239048,DB00059,10019211,40,787,43,1064,0.309910078,1.257485596,0.788396813,2.001847408,0.477350507,DB0005910019211_,0.739504243,0.229114169,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pegaspargase,DB00059
,239057,DB00541,10024264,19,3115,43,4254,0.070866576,0.603467398,0.331430484,1.060366522,0.162831491,DB0054110024264_,1.815039409,-0.505063261,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,vincristine,DB00541
,239104,DB00490,10011224,73,3997,17,1559,0.057937076,1.674779086,0.974076906,3.039506394,0.139598134,DB0049010011224_,1.968987452,0.515681268,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,buspirone,DB00490
,239197,DB00863,10022116,33,10640,17,5823,0.883447755,1.062356967,0.574428652,2.03541728,0.951268864,DB0086310022116_,0.04995854,0.060489993,NA,10022116,Injury,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,239258,DB00868,10038695,39,2945,35,1611,0.037390245,0.609588502,0.374622542,0.995405647,0.100362788,DB0086810038695_,2.298963779,-0.494971137,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,benzonatate,DB00868
,239262,DB00115,10039117,51,18374,42,10430,0.083496337,0.689325982,0.448828636,1.063686899,0.184273821,DB0011510039117_,1.691332467,-0.372040996,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,239284,DB00169,10041569,93,38598,44,18131,1,0.992858276,0.686169429,1.456058756,1,DB0016910041569_,0,-0.007167348,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,239367,DB00863,10062244,39,10634,12,5828,0.079848591,1.781116368,0.912789781,3.739463701,0.178160281,DB0086310062244_,1.72507168,0.577240341,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,239370,DB01075,10062244,54,19894,18,11079,0.064391145,1.670678609,0.963977108,3.028559353,0.151361228,DB0107510062244_,1.888086064,0.513229897,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,239390,DB00695,10070488,33,28016,17,20511,0.254912081,1.421157582,0.768968471,2.721151181,0.415616664,DB0069510070488_,0.877991925,0.351471738,NA,10070488,Upper-airway cough syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,239441,DB00535,10011224,36,1168,18,628,0.885315408,1.075307643,0.589210472,2.029009824,0.952246159,DB0053510011224_,0.048931707,0.0726068,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cefdinir,DB00535
,239454,DB00535,10016256,57,1147,30,616,1,1.020390587,0.637049291,1.66357597,1,DB0053510016256_,0,0.020185483,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cefdinir,DB00535
,239471,DB00745,10028810,42,2535,15,1068,0.662279731,1.179583749,0.637623055,2.300301589,0.794071057,DB0074510028810_,0.23058233,0.165161621,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,modafinil,DB00745
,239484,DB00230,10061458,42,19632,12,8639,0.23617563,1.540153739,0.795547374,3.215549702,0.393420574,DB0023010061458_,0.932876078,0.431882242,NA,10061458,Feeling of body temperature change,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,239514,DB08827,10005425,54,1108,25,557,0.807630304,1.085805561,0.656017288,1.841550043,0.896173697,DB0882710005425_,0.109621027,0.082322164,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,lomitapide,DB08827
,239542,DB00005,10043417,181,127901,72,42347,0.190434717,0.832304909,0.629909132,1.109764641,0.337121264,DB0000510043417_,1.087312579,-0.183556428,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,239543,DB00215,10043417,34,11069,17,5259,0.881127473,0.950224924,0.515765193,1.815439207,0.950230194,DB0021510043417_,0.051051015,-0.05105656,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,citalopram,DB00215
,239573,DB00924,10076309,81,10081,28,4223,0.4604168,1.211808472,0.778541936,1.937843878,0.627813949,DB0092410076309_,0.465511416,0.192113848,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,239656,DB00115,10051118,42,18383,8,10464,0.00280976,2.98831205,1.385291708,7.371690391,0.012811962,DB0011510051118_,4.357376024,1.094708696,female,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,239685,DB00169,10051076,37,38654,22,18153,0.402675815,0.789857989,0.453696121,1.406032499,0.572451056,DB0016910051076_,0.55782804,-0.235902111,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,239708,DB00472,10007882,43,10716,15,4297,0.77111426,1.149487408,0.625261351,2.23011154,0.874689322,DB0047210007882_,0.133886516,0.13931611,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,fluoxetine,DB00472
,239727,DB00472,10021789,70,10689,16,4296,0.041614881,1.758299997,1.009476029,3.247392008,0.108959772,DB0047210021789_,2.216776532,0.564347431,NA,10021789,Infection,10021881,Infections and infestations,Infec,fluoxetine,DB00472
,239782,DB00555,10038743,33,7014,22,3464,0.314357213,0.740797825,0.418424023,1.335959741,0.481955108,DB0055510038743_,0.729904306,-0.300027531,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,239837,DB06643,10042212,66,52355,6,7509,0.372206163,1.577660295,0.687160046,4.455467891,0.541853673,DB0664310042212_,0.61275929,0.455942924,NA,10042212,Stress fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,239838,DB06643,10070884,103,52318,8,7507,0.112490245,1.847389407,0.902792801,4.3950263,0.22981549,DB0664310070884_,1.47047851,0.613773511,NA,10070884,Atypical femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,239841,DB01065,10000059,50,4281,21,3030,0.052009557,1.685070473,0.991388918,2.960283888,0.128819363,DB0106510000059_,2.04934414,0.521807387,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,melatonin,DB01065
,239847,DB11133,10000081,32,2399,25,1549,0.496483084,0.826524231,0.472553654,1.460854809,0.658644755,DB1113310000081_,0.417570956,-0.190526045,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,omega-3 fatty acids,DB11133
,239868,DB01065,10020751,35,4296,17,3034,0.258045134,1.453948035,0.791284581,2.77296317,0.418957741,DB0106510020751_,0.869985221,0.374282639,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,melatonin,DB01065
,239877,DB11133,10028810,40,2391,17,1557,0.17167107,1.532060769,0.845557543,2.892909316,0.312989809,DB1113310028810_,1.161584649,0.426613737,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,omega-3 fatty acids,DB11133
,239892,DB01065,10037660,107,4224,107,2944,0.011050212,0.697018352,0.525858945,0.923878628,0.038535439,DB0106510037660_,3.256176959,-0.360943539,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,239945,DB04844,10051076,26,650,33,436,0.020349269,0.528776379,0.29912867,0.925997513,0.062654392,DB0484410051076_,2.770121496,-0.637189661,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,tetrabenazine,DB04844
,239954,DB01015,10028391,33,9854,18,9363,0.067499101,1.741925624,0.951966829,3.288252349,0.156860746,DB0101510028391_,1.852396832,0.554991182,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfamethoxazole,DB01015
,240037,DB01012,10021789,44,10588,25,8660,0.148091801,1.439487299,0.861043117,2.456564378,0.281364807,DB0101210021789_,1.268103205,0.364287008,NA,10021789,Infection,10021881,Infections and infestations,Infec,cinacalcet,DB01012
,240072,DB00007,10042772,8,1939,48,4404,0.008019426,0.378591544,0.154382877,0.809347265,0.029838009,DB0000710042772_,3.511972237,-0.971297376,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,leuprolide,DB00007
,240098,DB06403,10033775,94,21377,23,6638,0.328760873,1.269066709,0.796835469,2.10051227,0.497394281,DB0640310033775_,0.698372245,0.238281755,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,240099,DB06403,10052915,64,21407,8,6653,0.01169139,2.486324622,1.187974752,6.007316696,0.040321222,DB0640310052915_,3.210877344,0.910805565,NA,10052915,Catheter placement,10042613,Surgical and medical procedures,Surg,ambrisentan,DB06403
,240120,DB00065,10064355,44,9420,15,4942,0.170031089,1.538867278,0.839051165,2.98014578,0.310916357,DB0006510064355_,1.168231353,0.431046612,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,infliximab,DB00065
,240162,DB00273,10051118,56,8425,23,2170,0.068342698,0.627150886,0.378733014,1.070488857,0.158306923,DB0027310051118_,1.843219577,-0.46656812,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,240184,DB00213,10012267,34,18861,24,13397,1,1.00626064,0.5791044,1.774396582,1,DB0021310012267_,0,0.006241123,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,240216,DB00571,10002034,51,5072,32,2577,0.352345097,0.809797598,0.509078784,1.305570731,0.522088059,DB0057110002034_,0.649919009,-0.210970942,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,propranolol,DB00571
,240243,DB00571,10028334,48,5075,18,2591,0.297108773,1.361403951,0.775648075,2.492049613,0.462991203,DB0057110028334_,0.770047226,0.308516484,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,propranolol,DB00571
,240267,DB01012,10047895,35,10597,28,8657,1,1.021162505,0.602996536,1.744175464,1,DB0101210047895_,0,0.02094169,NA,10047895,Weight decreased,10022891,Investigations,Inv,cinacalcet,DB01012
,240346,DB00203,10070863,21,13857,63,8875,4.78172581887898e-11,0.213504896,0.123639771,0.355012356,1.64405053171006e-09,DB0020310070863_,20.2261028,-1.544095514,male,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,240505,DB00788,10040984,40,9316,10,5051,0.025643612,2.168639297,1.064616625,4.867654668,0.074922731,DB0078810040984_,2.591297951,0.774099919,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,naproxen,DB00788
,240506,DB01156,10040984,49,13573,22,6306,1,1.034758895,0.613340524,1.798808512,1,DB0115610040984_,0,0.034168448,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,240547,DB00065,10073317,40,9424,13,4944,0.148221574,1.614159707,0.844801224,3.292279189,0.281526022,DB0006510073317_,1.267530397,0.478814516,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,infliximab,DB00065
,240549,DB00959,10076309,104,7974,49,4953,0.131732162,1.318308873,0.928178513,1.894969102,0.25820879,DB0095910076309_,1.353986756,0.276349758,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,methylprednisolone,DB00959
,240590,DB00016,10069339,36,2726,28,2262,0.899580717,1.066874281,0.63085611,1.821287559,0.956532328,DB0001610069339_,0.044440693,0.064733141,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,erythropoietin,DB00016
,240591,DB01097,10000087,59,6206,8,1495,0.160456499,1.776474438,0.842809752,4.314745707,0.298111429,DB0109710000087_,1.210287939,0.574630747,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,leflunomide,DB01097
,240657,DB00959,10028735,41,8037,19,4983,0.351637274,1.337882041,0.758113737,2.443487994,0.521381229,DB0095910028735_,0.651273779,0.291087797,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,240678,DB08895,10043882,77,28037,17,6629,0.895790645,1.070953538,0.626921374,1.933487882,0.956196354,DB0889510043882_,0.044791996,0.068549409,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,tofacitinib,DB08895
,240687,DB08895,10049848,85,28029,18,6628,0.801701209,1.116657191,0.665326222,1.975188975,0.892739804,DB0889510049848_,0.113460114,0.110339571,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,240751,DB00268,10069339,42,2933,20,1525,0.789166476,1.091872684,0.624331438,1.97050556,0.885744089,DB0026810069339_,0.121327208,0.087894281,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ropinirole,DB00268
,240757,DB11133,10069339,25,2406,37,1537,0.001451208,0.431724813,0.248042359,0.739951664,0.007483814,DB1113310069339_,4.895012784,-0.8399669,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,omega-3 fatty acids,DB11133
,240857,DB00904,10017918,93,22976,21,14435,4.45220080889106e-06,2.782228163,1.717769278,4.70735151,5.34207774641903e-05,DB0090410017918_,9.837310797,1.023252104,female,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,ondansetron,DB00904
,240859,DB00999,10017918,40,21390,15,12224,0.206182698,1.523933702,0.823240442,2.971021204,0.356675917,DB0099910017918_,1.030927705,0.421294954,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,240881,DB00065,10046306,39,9425,16,4941,0.477953149,1.277865165,0.696975696,2.45188108,0.643286259,DB0006510046306_,0.441165461,0.245190846,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,infliximab,DB00065
,240884,DB00455,10046306,120,9281,45,5073,0.032925051,1.457565771,1.024801059,2.105361155,0.091117601,DB0045510046306_,2.395604289,0.376767764,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,loratadine,DB00455
,240892,DB00422,10011906,69,3366,67,2882,0.48747095,0.88178606,0.618410713,1.25794343,0.651307575,DB0042210011906_,0.428773283,-0.125805815,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,240975,DB00230,10028347,54,19620,12,8639,0.031595798,1.981380752,1.046231922,4.07189574,0.088214515,DB0023010028347_,2.427983755,0.683793951,NA,10028347,Muscle twitching,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,241030,DB01241,10019211,50,893,25,1046,0.000549435,2.341708307,1.408293577,3.984790742,0.003335315,DB0124110019211_,5.70318828,0.850880709,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,gemfibrozil,DB01241
,241044,DB00005,10024384,92,127990,22,42397,0.193354662,1.385213696,0.862469353,2.317712067,0.340855592,DB0000510024384_,1.076296376,0.325854421,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,etanercept,DB00005
,241182,DB01115,10028334,47,3553,22,2246,0.265134714,1.35041813,0.795316639,2.360017135,0.427078438,DB0111510028334_,0.850787587,0.30041427,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,nifedipine,DB01115
,241198,DB09038,10037087,34,2214,45,2496,0.497654579,0.851820533,0.52709714,1.365282933,0.659749362,DB0903810037087_,0.41589527,-0.160379416,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,empagliflozin,DB09038
,241215,DB00158,10019196,35,16780,24,8080,0.209915446,0.70221727,0.405674115,1.234859836,0.361054018,DB0015810019196_,1.018727698,-0.353512421,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,241268,DB00512,10037855,23,4714,33,5065,0.34799985,0.748889042,0.419192504,1.316691103,0.517575752,DB0051210037855_,0.658599383,-0.289164448,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,vancomycin,DB00512
,241276,DB00959,10064848,29,8049,34,4968,0.013011641,0.526465202,0.309023452,0.891588563,0.043912304,DB0095910064848_,3.125560731,-0.641570042,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,methylprednisolone,DB00959
,241334,DB00515,10010774,44,1826,32,2119,0.048499861,1.595428718,0.984417161,2.611469192,0.12226062,DB0051510010774_,2.101600281,0.467142489,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,cisplatin,DB00515
,241372,DB05676,10038435,31,47098,24,25305,0.202691674,0.693966543,0.394130369,1.236013114,0.352154844,DB0567610038435_,1.043684301,-0.365331529,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,apremilast,DB05676
,241400,DB00787,10029216,59,16941,18,17230,1.69291324566689e-06,3.333879368,1.937961343,6.008025587,2.29136069322113e-05,DB0078710029216_,10.68377963,1.204136601,female,10029216,Nervousness,10037175,Psychiatric disorders,Psych,acyclovir,DB00787
,241427,DB00028,10062244,35,13423,18,5597,0.454116629,0.810814056,0.44645448,1.522007326,0.621609457,DB0002810062244_,0.475443266,-0.209716529,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human immunoglobulin g,DB00028
,241430,DB00787,10062244,60,16940,39,17209,0.034089158,1.562861934,1.026619904,2.403821234,0.093585411,DB0078710062244_,2.368880773,0.446518714,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,241505,DB01115,10028411,61,3539,14,2254,0.000283247,2.774645359,1.529738796,5.384210882,0.001926389,DB0111510028411_,6.252107815,1.02052294,female,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,nifedipine,DB01115
,241519,DB00864,10065553,42,6827,35,8357,0.10753356,1.468877899,0.914422263,2.372704079,0.222464258,DB0086410065553_,1.50298883,0.384498775,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,tacrolimus,DB00864
,241564,DB00421,10040829,37,8866,14,5238,0.19087127,1.561343628,0.82350464,3.129623436,0.337653927,DB0042110040829_,1.085733794,0.44554675,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,spironolactone,DB00421
,241634,DB00480,10061148,94,67334,58,67604,0.003405618,1.627172667,1.160526696,2.298262219,0.014991227,DB0048010061148_,4.200290088,0.486843949,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,241681,DB00471,10052251,39,14150,11,5454,0.430683861,1.366510327,0.68576087,2.960821302,0.599175657,DB0047110052251_,0.512200473,0.312260283,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,241768,DB08932,10069339,235,19208,99,6498,0.07601561,0.803022126,0.631194023,1.02793326,0.171495057,DB0893210069339_,1.763200837,-0.219373011,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,macitentan,DB08932
,241779,DB00734,10014625,34,4016,17,4885,0.002708893,2.432542991,1.319529541,4.649775713,0.012437251,DB0073410014625_,4.387059189,0.888937209,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,241784,DB00734,10022523,41,4009,78,4824,0.020118226,0.632532859,0.421420669,0.937121127,0.062044768,DB0073410022523_,2.779899084,-0.458023109,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,241813,DB01118,10007554,38,3025,81,4628,0.107715461,0.717768834,0.473527128,1.071010702,0.222691978,DB0111810007554_,1.501965727,-0.331607719,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,amiodarone,DB01118
,241825,DB00887,10038435,56,2285,53,1762,0.327851184,0.814808759,0.546549983,1.216025378,0.49636082,DB0088710038435_,0.700452157,-0.204801844,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,bumetanide,DB00887
,241831,DB00887,10064848,31,2310,27,1788,0.690308781,0.888723083,0.511217363,1.553773987,0.813192592,DB0088710064848_,0.206787307,-0.117969584,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,bumetanide,DB00887
,241837,DB09038,10000081,41,2207,43,2498,0.741939195,1.079176496,0.683300495,1.702301519,0.852093841,DB0903810000081_,0.160058616,0.076198247,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,empagliflozin,DB09038
,241865,DB00737,10069339,33,2768,23,909,0.007653391,0.471276216,0.266949089,0.845313327,0.028750804,DB0073710069339_,3.54908955,-0.752310912,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,meclizine,DB00737
,241893,DB01234,10024378,40,31585,38,32850,0.734472981,1.09477699,0.684319758,1.754174981,0.846366607,DB0123410024378_,0.166802671,0.090550681,NA,10024378,Leukocytosis,10005329,Blood and lymphatic system disorders,Blood,dexamethasone,DB01234
,241982,DB08895,10024855,51,28063,19,6627,0.094124028,0.633879359,0.367572482,1.137693834,0.201930303,DB0889510024855_,1.599832676,-0.455896628,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,241989,DB01611,10039906,53,11860,10,2351,1,1.050623142,0.527985176,2.319700481,1,DB0161110039906_,0,0.049383457,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,hydroxychloroquine,DB01611
,241999,DB08895,10042772,44,28070,9,6637,0.861199491,1.155946152,0.556576789,2.694454024,0.934992198,DB0889510042772_,0.067217094,0.144919188,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,242005,DB08895,10055798,61,28053,15,6631,0.883973481,0.961251073,0.539356255,1.822303344,0.951636223,DB0889510055798_,0.049572436,-0.039519642,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,tofacitinib,DB08895
,242090,DB00193,10061225,45,19275,21,8681,0.894453731,0.965091772,0.562673065,1.70663211,0.955933901,DB0019310061225_,0.04506651,-0.035532082,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,242092,DB00331,10061225,35,24911,49,20703,0.020810317,0.593642321,0.373220867,0.935322886,0.063763966,DB0033110061225_,2.752567052,-0.521478294,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,242098,DB00761,10061225,35,15272,24,8601,0.497751372,0.821332781,0.474504702,1.444256015,0.659861042,DB0076110061225_,0.415726009,-0.196826916,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,242101,DB00193,10069339,259,19061,187,8515,1.11740576811659e-06,0.618735071,0.509731848,0.752178215,1.5782380771061e-05,DB0019310069339_,11.05661638,-0.480078094,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,tramadol,DB00193
,242117,DB00051,10067482,77,25654,24,11396,0.159780146,1.425229832,0.890718038,2.358484962,0.297163362,DB0005110067482_,1.213473253,0.354333087,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,242138,DB00480,10002653,55,67373,37,67625,0.060885968,1.492034265,0.96580405,2.328739624,0.145067774,DB0048010002653_,1.930554242,0.400140467,NA,10002653,Anosmia,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,242151,DB00736,10002198,48,10543,10,5543,0.005252306,2.523485818,1.259409014,5.5983911,0.021272246,DB0073610002198_,3.850352069,0.925641207,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,esomeprazole,DB00736
,242167,DB06228,10034476,55,15857,61,16015,0.642571902,0.910638941,0.620383831,1.333990402,0.779030804,DB0622810034476_,0.249704691,-0.093608793,NA,10034476,Pericardial haemorrhage,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,242170,DB00381,10018985,30,29330,44,22843,0.009419555,0.531033832,0.322237513,0.864235447,0.033933121,DB0038110018985_,3.383363735,-0.632929546,NA,10018985,Haemorrhage intracranial,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,242210,DB01306,10076309,35,4173,40,3826,0.355043128,0.802264909,0.493665135,1.29834732,0.52487675,DB0130610076309_,0.644591805,-0.220316415,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin aspart,DB01306
,242250,DB01065,10028334,72,4259,40,3011,0.246397393,1.272510999,0.850289529,1.928264754,0.405443564,DB0106510028334_,0.902773592,0.240992113,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,melatonin,DB01065
,242313,DB00112,10067482,106,5827,64,4027,0.431567599,1.144571032,0.82915966,1.590738836,0.599992296,DB0011210067482_,0.510838464,0.135029923,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,242366,DB01261,10028334,53,3728,35,3268,0.199137373,1.327382341,0.847693176,2.101849458,0.347989889,DB0126110028334_,1.055581854,0.283208838,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,sitagliptin,DB01261
,242403,DB00381,10037437,37,29323,47,22840,0.027554504,0.613201165,0.387368063,0.96416231,0.07923314,DB0038110037437_,2.535360628,-0.489062233,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,242411,DB01012,10042609,58,10574,50,8635,0.846301516,0.947318507,0.636981744,1.413174012,0.92280077,DB0101210042609_,0.080341919,-0.054119909,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,cinacalcet,DB01012
,242450,DB01373,10025197,49,22671,6,7375,0.017791782,2.656711933,1.136256354,7.590578389,0.056378178,DB0137310025197_,2.875673103,0.977089243,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,calcium,DB01373
,242467,DB00188,10037884,71,7815,70,8758,0.49812257,1.136665054,0.8042314,1.606910733,0.660136722,DB0018810037884_,0.41530831,0.128098584,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,bortezomib,DB00188
,242480,DB00188,10042682,49,7837,36,8792,0.063528501,1.526920851,0.971791348,2.419770347,0.14982922,DB0018810042682_,1.898259164,0.423253192,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,242483,DB00433,10042682,33,7623,17,6003,0.198501036,1.528599358,0.826391429,2.929065706,0.34726859,DB0043310042682_,1.057656764,0.424351864,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,242490,DB11089,10042682,35,10140,20,8387,0.22210162,1.44742959,0.812072729,2.648294476,0.376174799,DB1108910042682_,0.977701353,0.369789287,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,docusate,DB11089
,242563,DB01220,10013573,34,1260,21,1115,0.219892249,1.432516656,0.802389807,2.61389463,0.373302946,DB0122010013573_,0.985365001,0.359432797,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,rifaximin,DB01220
,242570,DB00047,10061623,33,9252,33,8485,0.805256089,0.917110864,0.548080074,1.534505997,0.894590507,DB0004710061623_,0.1113892,-0.086526916,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,242585,DB01015,10038153,32,9855,43,9338,0.16445712,0.705162235,0.431470752,1.141780164,0.30338636,DB0101510038153_,1.192748169,-0.349327382,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,242586,DB14500,10038153,47,7762,22,4051,0.705162536,1.114955729,0.657653253,1.9457687,0.823292569,DB1450010038153_,0.19444365,0.108814699,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,potassium,DB14500
,242598,DB06168,10025482,60,549,25,375,0.048761003,1.638579655,0.991122939,2.779611849,0.122725425,DB0616810025482_,2.097805737,0.493829803,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,canakinumab,DB06168
,242620,DB00620,10061623,34,4794,24,3108,0.78791552,0.918450573,0.527724275,1.622196097,0.885095921,DB0062010061623_,0.122059255,-0.085067188,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,242636,DB00635,10028606,33,33020,38,23756,0.053710541,0.624798343,0.379603378,1.023411862,0.131936038,DB0063510028606_,2.025438034,-0.470326333,NA,10028606,Myocarditis,10007541,Cardiac disorders,Card,prednisone,DB00635
,242700,DB00188,10066274,28,7858,35,8793,0.70561164,0.89520834,0.524089062,1.516175353,0.823597413,DB0018810066274_,0.194073445,-0.110698806,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,bortezomib,DB00188
,242702,DB00531,10066274,64,7188,85,6431,0.020602489,0.673670609,0.478390682,0.944622471,0.063267973,DB0053110066274_,2.760376028,-0.395013998,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,cyclophosphamide,DB00531
,242706,DB01234,10066274,90,31535,108,32780,0.319901435,0.866235799,0.647170549,1.157111666,0.488067792,DB0123410066274_,0.717300965,-0.143598123,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,dexamethasone,DB01234
,242726,DB00028,10003658,37,13421,30,5585,0.01002861,0.513234935,0.308213407,0.861135977,0.035648389,DB0002810003658_,3.334051316,-0.667021576,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,human immunoglobulin g,DB00028
,242729,DB00668,10003658,38,10053,42,4261,2.34343133402912e-05,0.383514504,0.24028578,0.610383393,0.000228688,DB0066810003658_,8.383152256,-0.95837784,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,epinephrine,DB00668
,242751,DB05351,10016173,59,2664,18,1113,0.311443409,1.369384732,0.792115753,2.478736132,0.478940472,DB0535110016173_,0.736178966,0.314361538,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,dexlansoprazole,DB05351
,242765,DB05351,10061428,43,2680,13,1118,0.375658491,1.379685521,0.724787741,2.808199249,0.545493733,DB0535110061428_,0.606063962,0.32185559,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,dexlansoprazole,DB05351
,242785,DB08911,10019211,41,1598,39,1709,0.651263057,1.124266339,0.703286624,1.799808546,0.785736555,DB0891110019211_,0.241133715,0.11713068,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,trametinib,DB08911
,242786,DB08912,10019211,47,1283,44,1490,0.33706452,1.2404244,0.798727825,1.929432065,0.506198595,DB0891210019211_,0.680826206,0.215453579,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,dabrafenib,DB08912
,242868,DB00564,10037844,73,2531,47,1416,0.499254843,0.868988374,0.590465621,1.289593916,0.661087306,DB0056410037844_,0.413869367,-0.140425533,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,carbamazepine,DB00564
,242923,DB00512,10076309,41,4696,33,5065,0.242981257,1.34000459,0.825092634,2.191383261,0.401266757,DB0051210076309_,0.913128843,0.292673039,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,vancomycin,DB00512
,242924,DB00787,10076309,46,16954,37,17211,0.323083201,1.262077527,0.8004634,2.002257336,0.49149185,DB0078710076309_,0.710309921,0.232759194,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,242926,DB01076,10076309,160,25587,131,25452,0.10009249,1.214923429,0.957689512,1.543452028,0.210915423,DB0107610076309_,1.556298067,0.194681053,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,243065,DB00972,10016173,57,2447,20,1159,0.269141505,1.349804972,0.794206014,2.383867321,0.43165443,DB0097210016173_,0.840129941,0.299960116,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,azelastine,DB00972
,243072,DB00437,10019974,35,6886,38,11508,0.069484628,1.539180805,0.943146912,2.505431141,0.160372607,DB0043710019974_,1.830255376,0.43125033,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,allopurinol,DB00437
,243263,DB01377,10020919,51,3745,22,2648,0.055822875,1.639008964,0.97352768,2.845370355,0.135760943,DB0137710020919_,1.996859712,0.494091769,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,magnesium oxide,DB01377
,243274,DB00820,10020642,79,11836,37,5779,0.921023313,1.042486483,0.6960459,1.58706211,0.965007709,DB0082010020642_,0.035619189,0.041608709,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,tadalafil,DB00820
,243309,DB00904,10064911,87,22982,16,14440,4.28808590877332e-07,3.416372325,1.988944691,6.243418095,6.73110409746831e-06,DB0090410064911_,11.90877137,1.228579264,female,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,243336,DB00924,10022095,52,10110,7,4244,0.002318017,3.117951895,1.409341945,8.145627406,0.01096932,DB0092410022095_,4.512652978,1.137176342,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,243347,DB00924,10053425,48,10114,7,4244,0.004652455,2.877057249,1.293039877,7.543249957,0.019291653,DB0092410053425_,3.948082768,1.056767983,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,243361,DB00373,10013968,49,1783,28,1259,0.413195063,1.235615568,0.756630437,2.053840999,0.582615788,DB0037310013968_,0.540227335,0.211569282,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,timolol,DB00373
,243414,DB06292,10016256,35,1322,33,1200,0.902549903,0.962729845,0.577031484,1.609478574,0.957195726,DB0629210016256_,0.043747388,-0.037982441,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dapagliflozin,DB06292
,243458,DB00321,10013946,42,7405,10,2840,0.213632653,1.610793951,0.793932197,3.605270012,0.365773943,DB0032110013946_,1.005739779,0.476727195,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,amitriptyline,DB00321
,243472,DB00814,10020772,107,8180,40,3375,0.648519701,1.103671619,0.759008862,1.633150262,0.783451619,DB0081410020772_,0.244045969,0.098642457,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,meloxicam,DB00814
,243532,DB00005,10069339,43,128039,27,42392,0.012077763,0.527313846,0.31844021,0.887520075,0.041347753,DB0000510069339_,3.185737195,-0.639959375,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,etanercept,DB00005
,243552,DB00820,10048334,39,11876,14,5802,0.380338618,1.360962734,0.722214826,2.715920132,0.550400559,DB0082010048334_,0.597108976,0.308192342,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,243565,DB01015,10019303,35,9852,26,9355,0.370841618,1.278226194,0.747077606,2.213074703,0.540525795,DB0101510019303_,0.615212918,0.245473331,NA,10019303,Heart rate increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,243573,DB01225,10033318,34,5010,18,4622,0.069468316,1.742499491,0.955331308,3.282114214,0.16034904,DB0122510033318_,1.830402338,0.555320571,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,enoxaparin,DB01225
,243638,DB01592,10054236,44,6232,24,3043,0.697794639,0.895206614,0.531446277,1.542213366,0.818262715,DB0159210054236_,0.200571827,-0.110700734,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,iron,DB01592
,243658,DB00684,10013700,47,2745,12,2336,6.0257223041865e-05,3.332274752,1.735455807,6.9174679,0.000517771,DB0068410013700_,7.565977739,1.20365518,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,tobramycin,DB00684
,243809,DB00275,10003988,46,2014,22,1215,0.447886873,1.261284945,0.739259251,2.213008545,0.615679024,DB0027510003988_,0.485029517,0.232130999,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,olmesartan,DB00275
,243833,DB01076,10017918,46,25701,28,25555,0.047317279,1.633499595,0.999225947,2.71503071,0.120051611,DB0107610017918_,2.119833539,0.490724704,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,243896,DB01050,10066901,54,18054,21,9350,0.329008182,1.331728997,0.790547606,2.32283153,0.497625231,DB0105010066901_,0.697908034,0.286478096,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,244041,DB11089,10028245,44,10131,16,8391,0.003972043,2.277540694,1.258932817,4.327380737,0.016982664,DB1108910028245_,4.075562206,0.823096218,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,docusate,DB11089
,244167,DB00404,10019075,21,19871,31,9831,9.52627111542858e-05,0.335160448,0.182944451,0.602570815,0.000764574,DB0040410019075_,7.176191537,-1.093145911,male,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,244174,DB00996,10019075,64,38889,34,22391,0.753497382,1.083804248,0.704015269,1.695203121,0.86133778,DB0099610019075_,0.14926854,0.080477303,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,244212,DB00381,10043431,36,29324,14,22873,0.031400914,2.005692155,1.055408469,4.026635278,0.087777626,DB0038110043431_,2.432948636,0.695989216,NA,10043431,Thinking abnormal,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,244218,DB00695,10043431,41,28008,15,20513,0.02088876,2.001846895,1.084477432,3.894813603,0.063959728,DB0069510043431_,2.749501641,0.694070202,NA,10043431,Thinking abnormal,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,244223,DB00285,10069339,105,10846,40,3678,0.564758381,0.890185817,0.611692376,1.318063618,0.716476376,DB0028510069339_,0.333410003,-0.116325055,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,venlafaxine,DB00285
,244227,DB00924,10069339,119,10043,91,4160,1.77058641167859e-05,0.541725396,0.407833819,0.721533973,0.00017931,DB0092410069339_,8.626395409,-0.612996055,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,cyclobenzaprine,DB00924
,244268,DB00888,10003041,63,614,77,688,0.656492631,0.91686653,0.634748194,1.320453781,0.789961033,DB0088810003041_,0.23577166,-0.086793368,NA,10003041,Application site erythema,10018065,General disorders and administration site conditions,Genrl,mechlorethamine,DB00888
,244269,DB00888,10003053,78,599,78,687,0.444994629,1.146800432,0.810773392,1.622072481,0.6130388,DB0088810003053_,0.48932705,0.136975832,NA,10003053,Application site pruritus,10018065,General disorders and administration site conditions,Genrl,mechlorethamine,DB00888
,244271,DB00888,10040880,36,641,44,721,0.731225434,0.920375643,0.567789754,1.483475852,0.843659931,DB0088810040880_,0.170005791,-0.082973385,NA,10040880,Skin irritation,10040785,Skin and subcutaneous tissue disorders,Skin,mechlorethamine,DB00888
,244299,DB01234,10005654,55,31570,33,32855,0.013716592,1.734477959,1.106236084,2.758246187,0.045797474,DB0123410005654_,3.083526347,0.55070648,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,244356,DB01203,10013968,39,660,20,485,0.224529596,1.432538391,0.803765003,2.627113908,0.379180855,DB0120310013968_,0.969741998,0.359447969,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nadolol,DB01203
,244382,DB00338,10019075,29,33645,30,22242,0.085320826,0.63906672,0.370015187,1.102227319,0.187286142,DB0033810019075_,1.67511766,-0.447746418,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,244423,DB00741,10027175,36,4058,17,3157,0.096059275,1.647353761,0.899709792,3.133777072,0.204861351,DB0074110027175_,1.585421865,0.499170219,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,hydrocortisone,DB00741
,244468,DB00281,10037423,51,11407,26,5645,0.903758644,0.970684329,0.593316279,1.623834378,0.957417047,DB0028110037423_,0.043516196,-0.029753962,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,244508,DB00281,10051792,91,11367,39,5632,0.512695718,1.15607436,0.785099928,1.730813826,0.672851533,DB0028110051792_,0.396230578,0.145030093,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,lidocaine,DB00281
,244532,DB00683,10069339,52,1532,76,1562,0.057796878,0.697689475,0.477096509,1.013546011,0.139336966,DB0068310069339_,1.970860061,-0.359981153,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,midazolam,DB00683
,244534,DB00741,10069339,80,4014,115,3059,1.43025363746514e-05,0.530201316,0.391904812,0.714371907,0.000148888,DB0074110069339_,8.812316296,-0.634498504,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,hydrocortisone,DB00741
,244537,DB00829,10069339,74,7978,63,4391,0.0119862,0.646484159,0.454772515,0.92150467,0.041116773,DB0082910069339_,3.191339133,-0.436206583,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,diazepam,DB00829
,244587,DB01234,10035669,19,31606,50,32838,0.000397233,0.394787269,0.219779648,0.681779534,0.002547272,DB0123410035669_,5.972732192,-0.929408218,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,244718,DB00028,10067482,335,13123,97,5518,0.001105783,1.452192788,1.152426213,1.843869526,0.005981171,DB0002810067482_,5.119138909,0.373074682,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,244725,DB05679,10054112,66,6865,30,4879,0.047687403,1.56349553,0.999270882,2.498091783,0.120740103,DB0567910054112_,2.114114955,0.446924039,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,ustekinumab,DB05679
,244759,DB00425,10054112,117,12578,53,7431,0.111489617,1.304187788,0.9337433,1.842399367,0.228267999,DB0042510054112_,1.477234906,0.265580462,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,zolpidem,DB00425
,244765,DB00863,10054112,136,10537,85,5755,0.357174764,0.873885367,0.660244483,1.162130997,0.526901934,DB0086310054112_,0.640740831,-0.134806071,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,ranitidine,DB00863
,244771,DB00480,10017964,46,67382,39,67623,0.44967642,1.183702899,0.755649925,1.862684602,0.617299631,DB0048010017964_,0.482400747,0.168647575,NA,10017964,Gastrointestinal infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,244784,DB08890,10011906,37,1910,23,536,0.004331028,0.451612261,0.258770762,0.803521603,0.01822186,DB0889010011906_,4.005133295,-0.794931298,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,linaclotide,DB08890
,244802,DB00737,10000087,45,2756,6,926,0.032687622,2.519632775,1.066787181,7.250848676,0.090591902,DB0073710000087_,2.40139045,0.924113167,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,meclizine,DB00737
,244806,DB00924,10000087,132,10030,27,4224,0.000315603,2.058802621,1.350577281,3.246034457,0.002103623,DB0092410000087_,6.164094328,0.722124562,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,244851,DB00482,10013946,65,8194,12,3059,0.020569818,2.022091036,1.080668891,4.118699916,0.063192809,DB0048210013946_,2.761564765,0.704132142,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,celecoxib,DB00482
,244941,DB01015,10028735,44,9843,29,9352,0.12893908,1.441524151,0.881119767,2.39129124,0.254060249,DB0101510028735_,1.370183838,0.365700992,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfamethoxazole,DB01015
,244950,DB01175,10028735,71,10653,12,4880,0.000523864,2.710207843,1.457329299,5.495825662,0.003208241,DB0117510028735_,5.742032409,0.997025327,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,244956,DB00410,10028813,113,1492,36,973,0.000175813,2.04648803,1.381706327,3.094293471,0.00129392,DB0041010028813_,6.650078874,0.716125168,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,mupirocin,DB00410
,244988,DB00959,10039101,48,8030,20,4982,0.168219291,1.488972679,0.865905833,2.651940601,0.308472447,DB0095910039101_,1.176122753,0.398086405,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,244996,DB01104,10039101,78,15385,18,7268,0.004268962,2.047046234,1.213352731,3.635040651,0.018011182,DB0110410039101_,4.016762504,0.716397893,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,245012,DB00455,10050584,65,9336,20,5098,0.022788908,1.774625039,1.059782277,3.097247963,0.068391441,DB0045510050584_,2.682507593,0.573589155,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,245025,DB01060,10050584,61,8526,21,5060,0.029596504,1.723849939,1.033449195,2.984563808,0.083821726,DB0106010050584_,2.479063049,0.544560126,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,amoxicillin,DB01060
,245028,DB01104,10050584,132,15331,24,7262,2.61235902039996e-06,2.605152187,1.675494701,4.214164713,3.34792086061496e-05,DB0110410050584_,10.30458595,0.957491095,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,245031,DB01175,10050584,96,10628,29,4863,0.052642689,1.514660611,0.989268774,2.384036624,0.129987139,DB0117510050584_,2.040319766,0.415191395,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,245043,DB00316,10064366,52,65422,24,36929,0.474023697,1.222981287,0.740354512,2.074930928,0.63978996,DB0031610064366_,0.446615344,0.201291556,NA,10064366,Extra dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,245049,DB00455,10064366,168,9233,110,5008,0.128691951,0.828418053,0.645874243,1.066069738,0.253754017,DB0045510064366_,1.371389919,-0.188237358,NA,10064366,Extra dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,245087,DB06637,10061623,52,6110,26,1993,0.085622384,0.652410975,0.398813175,1.09158079,0.187743368,DB0663710061623_,1.672679311,-0.427080586,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,245094,DB08908,10008796,76,10597,23,3256,1,1.015285235,0.628492752,1.699597495,1,DB0890810008796_,0,0.015169593,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,dimethyl fumarate,DB08908
,245175,DB09053,10018867,13,2272,47,4005,0.021092578,0.487622313,0.241520068,0.918550085,0.064478505,DB0905310018867_,2.741423371,-0.718214122,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,ibrutinib,DB09053
,245177,DB00115,10038063,45,18380,36,10436,0.132813524,0.709773001,0.447400294,1.133201058,0.259718297,DB0011510038063_,1.348157709,-0.342810077,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,245227,DB00404,10017918,42,19850,11,9851,0.058008659,1.894820408,0.958226938,4.082502709,0.13970697,DB0040410017918_,1.968208123,0.639124062,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,alprazolam,DB00404
,245305,DB05679,10003988,56,6875,25,4884,0.054666471,1.591233805,0.975048726,2.665162634,0.133765423,DB0567910003988_,2.011667585,0.464509693,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ustekinumab,DB05679
,245321,DB00193,10006451,221,19099,49,8653,1.68382269868883e-06,2.043349681,1.491957951,2.847776588,2.28140616675443e-05,DB0019310006451_,10.68813347,0.714590462,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,tramadol,DB00193
,245331,DB01261,10006451,31,3750,24,3279,0.685991248,1.129404033,0.640131431,2.015487492,0.810449242,DB0126110006451_,0.210166566,0.121690089,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,sitagliptin,DB01261
,245343,DB06724,10019303,41,7888,12,3907,0.109964286,1.69223878,0.871337029,3.541349351,0.226010203,DB0672410019303_,1.487175136,0.526052374,NA,10019303,Heart rate increased,10022891,Investigations,Inv,calcium carbonate,DB06724
,245345,DB14500,10019303,73,7736,17,4056,0.001667967,2.251281436,1.312387033,4.078209866,0.008379684,DB1450010019303_,4.781945122,0.811499581,NA,10019303,Heart rate increased,10022891,Investigations,Inv,potassium,DB14500
,245348,DB00540,10020772,45,2438,10,1081,0.054006883,1.994952118,0.986508872,4.456529947,0.132490636,DB0054010020772_,2.021243306,0.690620049,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,nortriptyline,DB00540
,245383,DB14500,10033557,84,7725,15,4058,2.61880182987122e-05,2.941502477,1.683126028,5.495702913,0.000251315,DB1450010033557_,8.288803025,1.078920497,female,10033557,Palpitations,10007541,Cardiac disorders,Card,potassium,DB14500
,245404,DB00390,10055798,39,4106,22,3279,0.198718783,1.415611148,0.816971857,2.511882285,0.347491814,DB0039010055798_,1.057014172,0.347561344,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,digoxin,DB00390
,245405,DB00471,10055798,48,14141,18,5447,1,1.027192868,0.585989542,1.878062227,1,DB0047110055798_,0,0.026829711,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,montelukast,DB00471
,245456,DB00381,10074903,115,29245,75,22812,0.241607758,1.196042612,0.885967608,1.622849094,0.399689087,DB0038110074903_,0.917068316,0.179018284,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,245493,DB00557,10042674,61,5926,20,3047,0.098017238,1.568161183,0.93104026,2.749285866,0.207898576,DB0055710042674_,1.570704934,0.449903712,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,245577,DB00624,10005815,8,554,67,4329,1,0.933029835,0.384919636,1.960071689,1,DB0062410005815_,0,-0.069318101,NA,10005815,Blood testosterone increased,10022891,Investigations,Inv,testosterone,DB00624
,245656,DB08932,10007598,104,19339,32,6565,0.692944043,1.103270777,0.735244079,1.696871501,0.815000299,DB0893210007598_,0.204566799,0.098279201,NA,10007598,Cardiac pacemaker insertion,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,245661,DB00442,10011906,30,409,81,521,0.000731593,0.472112429,0.293673209,0.742226817,0.004244077,DB0044210011906_,5.46223096,-0.750538124,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,entecavir,DB00442
,245664,DB00688,10023232,31,6459,22,5356,0.678662993,1.168445508,0.654209286,2.120711333,0.805455399,DB0068810023232_,0.216347448,0.15567424,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,mycophenolate mofetil,DB00688
,245879,DB08816,10013710,15,1136,42,1860,0.096851905,0.58485404,0.299802294,1.082345834,0.20605871,DB0881610013710_,1.579594151,-0.536392967,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ticagrelor,DB08816
,245986,DB00455,10019974,53,9348,17,5101,0.059753147,1.701174625,0.96835402,3.137586362,0.143020082,DB0045510019974_,1.944770224,0.531318968,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,loratadine,DB00455
,246001,DB00904,10034835,43,23026,27,14429,1,0.997981313,0.602513827,1.680276925,1,DB0090410034835_,0,-0.002020728,NA,10034835,Pharyngitis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,246009,DB00904,10040984,48,23021,23,14433,0.329503999,1.308406758,0.780046518,2.254714634,0.498174492,DB0090410040984_,0.696804878,0.268810182,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,246102,DB01013,10037087,35,982,17,590,0.560838992,1.236784712,0.66762587,2.376467984,0.713380576,DB0101310037087_,0.337740234,0.212515038,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,clobetasol propionate,DB01013
,246123,DB15566,10013709,42,965,38,624,0.159897301,0.714862782,0.444290975,1.153354137,0.297318942,DB1556610013709_,1.212949838,-0.335664668,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,prednisolone acetate,DB15566
,246199,DB01373,10076309,139,22581,24,7357,0.003308201,1.886822296,1.21628887,3.046666961,0.014642764,DB0137310076309_,4.223808982,0.634894089,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,246207,DB08910,10014011,55,16689,42,17446,0.12824395,1.368903928,0.898972609,2.097895443,0.253155513,DB0891010014011_,1.373751302,0.314010367,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,246213,DB00472,10046306,65,10694,17,4295,0.140695088,1.535642203,0.888296085,2.797865942,0.270819112,DB0047210046306_,1.306304164,0.428948667,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,fluoxetine,DB00472
,246227,DB05676,10008469,78,47051,49,25280,0.402538039,0.855286309,0.590586618,1.24919994,0.572348058,DB0567610008469_,0.55800798,-0.156319002,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,246236,DB05676,10042209,431,46698,93,25236,3.08225647609157e-18,2.504444059,1.996246901,3.169966899,2.71414108790844e-16,DB0567610042209_,35.84288594,0.918066777,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,246287,DB06413,10017577,38,1518,13,661,0.538441943,1.272664189,0.65793331,2.621635536,0.694350511,DB0641310017577_,0.364778387,0.24111249,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,armodafinil,DB06413
,246350,DB00476,10040026,689,16568,258,5919,0.522378654,0.954063722,0.823066212,1.108560509,0.680961055,DB0047610040026_,0.384250162,-0.047024815,NA,10040026,Sensory disturbance,10029205,Nervous system disorders,Nerv,duloxetine,DB00476
,246357,DB08868,10040026,42,9160,19,2492,0.083329161,0.601409884,0.341457094,1.096944366,0.184015584,DB0886810040026_,1.692734828,-0.508478574,NA,10040026,Sensory disturbance,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,246408,DB00230,10061224,148,19526,60,8591,0.65043229,1.085273245,0.797903231,1.492165243,0.785013507,DB0023010061224_,0.242054356,0.081831794,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,246410,DB00476,10061224,49,17208,19,6158,0.783062989,0.922889901,0.533022254,1.661380532,0.881832675,DB0047610061224_,0.125752951,-0.080245336,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,246425,DB00341,10048393,68,11337,13,5055,0.003502893,2.332223248,1.275475669,4.60661322,0.015332811,DB0034110048393_,4.177760237,0.846821996,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,246467,DB00787,10013781,81,16919,29,17219,4.17230198496619e-07,2.842661847,1.838232206,4.509958592,6.57487755844342e-06,DB0078710013781_,11.9322546,1.044740883,female,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,246485,DB08932,10022972,50,19393,11,6586,0.237833111,1.543597016,0.792619711,3.290300486,0.395310695,DB0893210022972_,0.928083253,0.434115417,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,macitentan,DB08932
,246488,DB00374,10043882,44,17672,12,5712,0.755372212,1.18513995,0.614795052,2.466744963,0.862752671,DB0037410043882_,0.147627221,0.169860869,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,treprostinil,DB00374
,246489,DB08932,10043882,61,19382,18,6579,0.697897172,1.150311438,0.670252416,2.069772092,0.818262916,DB0893210043882_,0.200571581,0.140032721,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,macitentan,DB08932
,246536,DB00497,10012374,36,19231,25,16350,0.520652113,1.2242654,0.714544283,2.128520287,0.679729842,DB0049710012374_,0.38605985,0.202340991,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,246576,DB06403,10048294,51,21420,22,6639,0.213894422,0.71851592,0.427638132,1.245173072,0.366101119,DB0640310048294_,1.004845702,-0.330567417,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,ambrisentan,DB06403
,246795,DB01175,10006093,42,10682,36,4856,0.0067007,0.530360923,0.331233549,0.853183093,0.025871819,DB0117510006093_,3.654600972,-0.634197517,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,escitalopram,DB01175
,246797,DB09072,10006093,42,6429,19,2516,0.571167867,0.865122107,0.491063841,1.578238197,0.721482994,DB0907210006093_,0.326446471,-0.144884618,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,sodium oxybate,DB09072
,246836,DB00451,10061273,42,47229,17,15402,0.45078856,0.805686131,0.448783067,1.510071179,0.618454893,DB0045110061273_,0.48053102,-0.216061027,NA,10061273,Malnutrition,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,246884,DB00433,10039906,49,7607,21,5999,0.021224357,1.840010665,1.081676457,3.234101634,0.064809737,DB0043310039906_,2.736299431,0.609771368,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,246885,DB00512,10039906,48,4689,43,5055,0.400339063,1.203385201,0.779040779,1.864033593,0.570193261,DB0051210039906_,0.561779921,0.185138586,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,vancomycin,DB00512
,246931,DB09270,10020751,43,3071,18,2350,0.036780515,1.827831376,1.029120603,3.376298453,0.099137949,DB0927010020751_,2.311242976,0.603130224,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ubidecarenone,DB09270
,246938,DB00437,10054236,42,6879,43,11503,0.024782033,1.633187417,1.040582365,2.561901967,0.073021493,DB0043710054236_,2.617001457,0.490533576,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,allopurinol,DB00437
,247012,DB08893,10033425,41,2044,14,1044,0.249029224,1.495628177,0.794341472,2.984681094,0.408431857,DB0889310033425_,0.895430192,0.402546304,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,mirabegron,DB08893
,247055,DB08893,10047700,44,2041,13,1045,0.089799136,1.732662365,0.911618955,3.522703382,0.194894748,DB0889310047700_,1.635295618,0.549659165,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,mirabegron,DB08893
,247065,DB00254,10076308,41,5894,26,3362,0.702808684,0.899506466,0.536139958,1.534534944,0.821701075,DB0025410076308_,0.196378605,-0.105909037,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,doxycycline,DB00254
,247069,DB00829,10076308,58,7994,35,4419,0.665663904,0.91605951,0.591017482,1.438473011,0.796638775,DB0082910076308_,0.227353934,-0.087673949,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,247161,DB00331,10024264,90,24856,75,20677,1,0.998245897,0.7261777,1.37560395,1,DB0033110024264_,0,-0.001755643,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,metformin,DB00331
,247189,DB00761,10023232,117,15190,43,8582,0.016353794,1.537236629,1.074003451,2.236583113,0.05271134,DB0076110023232_,2.942924673,0.429986408,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium chloride,DB00761
,247259,DB00635,10003983,33,33020,24,23770,1,0.989815272,0.567343951,1.750633632,1,DB0063510003983_,0,-0.010236947,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,247261,DB00695,10003983,36,28013,33,20495,0.393572267,0.798145492,0.483518311,1.321391266,0.563501759,DB0069510003983_,0.573584823,-0.225464377,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,247274,DB00575,10021789,42,5202,23,3806,0.313517371,1.335998745,0.783756898,2.331545936,0.481029265,DB0057510021789_,0.731827169,0.289679136,NA,10021789,Infection,10021881,Infections and infestations,Infec,clonidine,DB00575
,247314,DB00776,10046571,46,1859,8,1331,3.57106007249665e-05,4.115410836,1.915231586,10.13047869,0.000330686,DB0077610046571_,8.014340284,1.414738668,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,oxcarbazepine,DB00776
,247321,DB00480,10047461,173,67255,143,67519,0.0910499,1.214535371,0.967336292,1.526910089,0.196942612,DB0048010047461_,1.624842904,0.194361593,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,247323,DB01234,10047461,75,31550,74,32814,0.805707097,1.054139604,0.753975238,1.474021626,0.894887901,DB0123410047461_,0.111056819,0.052724893,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,247331,DB00213,10017413,131,18764,95,13326,0.892354026,0.979307893,0.745547911,1.290394843,0.955096839,DB0021310017413_,0.045942542,-0.020909189,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,247344,DB00480,10042727,58,67370,32,67630,0.006008366,1.819475709,1.161903735,2.895977498,0.023691854,DB0048010042727_,3.742624003,0.598548387,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,247355,DB00480,10025409,47,67381,20,67642,0.000894512,2.359221688,1.370748512,4.203601249,0.005025059,DB0048010025409_,5.293318052,0.858331771,NA,10025409,Macular degeneration,10015919,Eye disorders,Eye,lenalidomide,DB00480
,247467,DB00279,10013968,48,1189,8,208,1,1.049598369,0.482970288,2.606832622,1,DB0027910013968_,0,0.048407585,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,liothyronine,DB00279
,247478,DB00254,10016807,35,5900,15,3373,0.38018972,1.333915259,0.70864356,2.632973447,0.55033658,DB0025410016807_,0.597225224,0.288118422,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,doxycycline,DB00254
,247583,DB00158,10054112,163,16652,91,8013,0.281338042,0.861950241,0.66192223,1.128191685,0.445306645,DB0015810054112_,0.808992145,-0.148557735,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,folic acid,DB00158
,247586,DB00448,10054112,56,5089,35,3089,0.91362974,0.971178053,0.623884022,1.530509093,0.961320912,DB0044810054112_,0.03944699,-0.029245456,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,lansoprazole,DB00448
,247588,DB00829,10054112,50,8002,30,4424,0.72637741,0.921443811,0.57365864,1.503279887,0.839835939,DB0082910054112_,0.174548717,-0.081813479,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,diazepam,DB00829
,247590,DB00959,10054112,46,8032,19,4983,0.159133149,1.501960318,0.861684495,2.717768867,0.296319473,DB0095910054112_,1.216317104,0.406771133,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,methylprednisolone,DB00959
,247601,DB00215,10013887,33,11070,18,5258,0.653680406,0.870807505,0.475748308,1.644279689,0.787749099,DB0021510013887_,0.238575642,-0.138334331,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,247707,DB06643,10006451,127,52294,15,7500,0.610926797,1.214262621,0.708581152,2.234700604,0.752987474,DB0664310006451_,0.283706686,0.194136996,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,denosumab,DB06643
,247709,DB06643,10037153,52,52369,7,7508,1,1.065020447,0.481670082,2.780224337,1,DB0664310037153_,0,0.062993998,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,247715,DB01137,10076309,34,7738,27,5566,0.698628876,0.905802147,0.529817671,1.56277875,0.818810362,DB0113710076309_,0.19990277,-0.098934378,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,levofloxacin,DB01137
,247787,DB01060,10005750,59,8528,29,5052,0.440348659,1.20525885,0.759162165,1.95283903,0.608707047,DB0106010005750_,0.496418166,0.186694357,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,amoxicillin,DB01060
,247794,DB01060,10069327,36,8551,19,5062,0.780283282,1.121651482,0.625761977,2.072385612,0.880397753,DB0106010069327_,0.127381481,0.114802136,NA,10069327,Product quality issue,10077536,Product issues,Prod,amoxicillin,DB01060
,247803,DB00068,10039906,42,2192,9,656,0.500803609,1.396428296,0.66554712,3.28026535,0.662303985,DB0006810039906_,0.412030636,0.333917759,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,interferon beta-1b,DB00068
,247977,DB06228,10007610,16,15896,36,16040,0.007779567,0.448451762,0.232267028,0.829427453,0.02911868,DB0622810007610_,3.536375385,-0.801954158,NA,10007610,Cardiac tamponade,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,248041,DB00635,10023804,38,33015,33,23761,0.470683551,0.828756208,0.505938216,1.363913394,0.636923326,DB0063510023804_,0.451105998,-0.187829247,NA,10023804,Large intestine perforation,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,248071,DB00433,10069339,162,7494,163,5857,0.02728903,0.776783996,0.619347725,0.974177408,0.078646143,DB0043310069339_,2.542796689,-0.252592965,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,prochlorperazine,DB00433
,248072,DB00646,10069339,87,3366,64,1936,0.145877746,0.78191419,0.556797147,1.102854387,0.278272068,DB0064610069339_,1.279155982,-0.246010276,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,nystatin,DB00646
,248099,DB00924,10008531,101,10061,29,4222,0.081574909,1.461514528,0.957142603,2.2953091,0.180997338,DB0092410008531_,1.709272954,0.379473246,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,248163,DB08895,10009887,40,28074,11,6635,0.596993245,0.859390431,0.432487338,1.858218071,0.742340632,DB0889510009887_,0.297947069,-0.151531942,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,248164,DB00958,10002855,62,4532,10,2575,3.5535441778698e-05,3.52224111,1.788829711,7.717706925,0.000329354,DB0095810002855_,8.018376174,1.259097466,female,10002855,Anxiety,10037175,Psychiatric disorders,Psych,carboplatin,DB00958
,248193,DB00213,10031127,22,18873,34,13387,0.004175896,0.45897835,0.255609665,0.808258079,0.01768795,DB0021310031127_,4.034871672,-0.778752239,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,pantoprazole,DB00213
,248303,DB08907,10040047,34,4219,41,3869,0.247604379,0.760502747,0.467066857,1.231069834,0.406869286,DB0890710040047_,0.899263309,-0.273775555,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,canagliflozin,DB08907
,248357,DB00213,10036018,56,18839,33,13388,0.451152875,1.205938951,0.770281027,1.915432554,0.618825513,DB0021310036018_,0.479931931,0.187258476,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,248453,DB06317,10035226,43,560,47,673,0.66302544,1.099426275,0.698448182,1.726922118,0.794569675,DB0631710035226_,0.2299546,0.094788475,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,elotuzumab,DB06317
,248458,DB06317,10037660,30,573,30,690,0.50891332,1.204014504,0.692138463,2.09460226,0.669437756,DB0631710037660_,0.401317089,0.185661393,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,elotuzumab,DB06317
,248486,DB00268,10008479,53,2922,21,1524,0.324100327,1.316263646,0.77716886,2.306492711,0.492526065,DB0026810008479_,0.708207896,0.274797151,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,248498,DB00514,10033295,35,2131,51,1485,0.000834801,0.478325558,0.300317788,0.75418978,0.004743864,DB0051410033295_,5.350903219,-0.737463695,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,dextromethorphan,DB00514
,248517,DB00497,10023424,41,19226,15,16360,0.004453211,2.325759192,1.259877965,4.525138519,0.018618204,DB0049710023424_,3.983615489,0.84404652,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,oxycodone,DB00497
,248562,DB00332,10047899,40,2644,12,1644,0.030207551,2.072301783,1.062034601,4.352429969,0.085145453,DB0033210047899_,2.463394277,0.728659962,NA,10047899,Weight increased,10022891,Investigations,Inv,ipratropium,DB00332
,248658,DB00281,10002198,71,11387,51,5620,0.042872947,0.687089378,0.472085598,1.006325411,0.111459909,DB0028110002198_,2.194090316,-0.375290897,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,lidocaine,DB00281
,248661,DB00683,10002198,41,1543,22,1616,0.010963938,1.951396581,1.12953728,3.456592402,0.038314032,DB0068310002198_,3.261939087,0.668545312,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,midazolam,DB00683
,248677,DB01098,10000087,122,8027,81,7128,0.047303103,1.337458188,0.999744677,1.797205239,0.120033022,DB0109810000087_,2.119988387,0.290770938,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,rosuvastatin,DB01098
,248693,DB01224,10057362,39,8069,41,5876,0.111917089,0.692726392,0.434580212,1.102565592,0.228982226,DB0122410057362_,1.474110895,-0.367120175,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,248860,DB00281,10051118,150,11308,51,5620,0.019312334,1.461714617,1.055413772,2.053346676,0.060152233,DB0028110051118_,2.81087672,0.379610142,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,248864,DB00813,10051118,35,10537,19,10149,0.055385221,1.77421717,0.986736157,3.285697393,0.134983823,DB0081310051118_,2.00260034,0.573359294,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,248933,DB00571,10010305,54,5069,24,2585,0.631428084,1.147384932,0.695380204,1.94556598,0.77027369,DB0057110010305_,0.261009386,0.137485381,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,propranolol,DB00571
,248945,DB14500,10021789,83,7726,36,4037,0.383255485,1.204655846,0.803809594,1.837923577,0.553311753,DB1450010021789_,0.591833687,0.186193921,NA,10021789,Infection,10021881,Infections and infestations,Infec,potassium,DB14500
,248963,DB00451,10038683,98,47173,24,15395,0.246648554,1.332583327,0.845449277,2.179128369,0.40571958,DB0045110038683_,0.902093047,0.287119409,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,248967,DB01076,10038683,41,25706,33,25550,0.415824729,1.234877127,0.761526141,2.016446082,0.585033844,DB0107610038683_,0.53608558,0.210971473,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,249005,DB00115,10042609,80,18345,18,10454,0.000133141,2.532617926,1.503846418,4.491443665,0.001017476,DB0011510042609_,6.890430455,0.929253521,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,cyanocobalamin,DB00115
,249014,DB00656,10042609,42,11971,13,6606,0.067597997,1.782795937,0.937973527,3.622517795,0.157022006,DB0065610042609_,1.851369318,0.578182883,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,trazodone,DB00656
,249050,DB01043,10013709,71,1330,76,1334,0.735008729,0.937013412,0.662128451,1.324790044,0.846827671,DB0104310013709_,0.166258063,-0.065057683,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,memantine,DB01043
,249069,DB00656,10000381,32,11981,52,6567,9.39062336347284e-07,0.337323903,0.20989426,0.534573237,1.354394221185e-05,DB0065610000381_,11.20957118,-1.086711675,male,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,249077,DB01050,10067482,51,18057,18,9353,0.202991815,1.467564844,0.842388422,2.670739703,0.352571438,DB0105010067482_,1.042502016,0.383604459,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,249101,DB00451,10064366,46,47225,11,15408,0.441771566,1.364368822,0.695943355,2.921964577,0.609894929,DB0045110064366_,0.494468584,0.31069192,NA,10064366,Extra dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,249112,DB00788,10019303,43,9313,13,5048,0.068204585,1.792828633,0.945232771,3.637580459,0.158063615,DB0078810019303_,1.844757699,0.583794615,NA,10019303,Heart rate increased,10022891,Investigations,Inv,naproxen,DB00788
,249215,DB09079,10019211,52,605,28,849,6.21923117799626e-05,2.604507997,1.59369356,4.336229831,0.000531186,DB0907910019211_,7.540398315,0.957243789,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,nintedanib,DB09079
,249224,DB00207,10060795,22,9058,33,5422,0.000742958,0.399082066,0.221424945,0.70619684,0.004300518,DB0020710060795_,5.44901982,-0.918588203,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,azithromycin,DB00207
,249230,DB00761,10060795,55,15252,17,8608,0.027128377,1.825908538,1.043200862,3.358059151,0.078294746,DB0076110060795_,2.547274776,0.602077692,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,potassium chloride,DB00761
,249291,DB00193,10029412,36,19284,26,8676,0.073609399,0.622958632,0.365588885,1.075163593,0.167524399,DB0019310029412_,1.786626272,-0.473275163,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,249292,DB00264,10029412,41,29566,36,24856,0.908997755,0.9574401,0.596693364,1.542372962,0.95913476,DB0026410029412_,0.041723693,-0.043492118,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,249293,DB00381,10029412,38,29322,38,22849,0.298554474,0.779253497,0.483589328,1.255650185,0.464541784,DB0038110029412_,0.766703769,-0.249418873,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,249327,DB01296,10037087,43,1406,17,966,0.061792806,1.737472403,0.963805479,3.269689865,0.146756168,DB0129610037087_,1.918982788,0.552431415,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,glucosamine,DB01296
,249329,DB00169,10039674,74,38617,17,18158,0.006575534,2.046762498,1.19576246,3.700861988,0.025481043,DB0016910039674_,3.669820534,0.716259276,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,249332,DB06643,10039674,88,52333,8,7507,0.278578663,1.577903118,0.766243126,3.770142765,0.442378751,DB0664310039674_,0.815588861,0.456096825,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,249355,DB00868,10037087,58,2926,20,1626,0.073310288,1.611397582,0.95083287,2.839160807,0.167038915,DB0086810037087_,1.789528468,0.477101866,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,benzonatate,DB00868
,249374,DB01136,10020100,40,9844,29,11086,0.071125154,1.553288378,0.938428332,2.600097357,0.163263005,DB0113610020100_,1.81239285,0.440374218,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,249398,DB00904,10042609,66,23003,17,14439,0.000617979,2.436896466,1.412517492,4.432844022,0.003690466,DB0090410042609_,5.602002413,0.890725289,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,ondansetron,DB00904
,249399,DB01075,10042609,42,19906,13,11084,0.067122981,1.798915377,0.946762636,3.65416423,0.156197385,DB0107510042609_,1.856634786,0.587183915,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,diphenhydramine,DB01075
,249412,DB09153,10050584,57,7742,21,5678,0.005699902,1.990555218,1.186636528,3.460941073,0.022720947,DB0915310050584_,3.784467989,0.688413604,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium chloride,DB09153
,249455,DB01373,10061016,37,22683,13,7368,0.869255537,0.924495406,0.479982625,1.896600128,0.941838249,DB0137310061016_,0.059921729,-0.078507197,NA,10061016,Blood test abnormal,10022891,Investigations,Inv,calcium,DB01373
,249473,DB00820,10023232,93,11822,29,5787,0.033273055,1.569774614,1.023553993,2.474160348,0.09186306,DB0082010023232_,2.387456291,0.450932051,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,249592,DB09054,10037660,18,406,33,548,0.382776265,0.736448646,0.384598918,1.368607567,0.552878016,DB0905410037660_,0.592617888,-0.305915773,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,idelalisib,DB09054
,249593,DB00341,10069339,75,11330,67,5001,4.88673212520385e-05,0.494105676,0.350021549,0.698761693,0.000433506,DB0034110069339_,7.743605496,-0.705005867,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,cetirizine,DB00341
,249690,DB00213,10017412,61,18834,36,13385,0.409995044,1.204193574,0.78440148,1.87314203,0.579402268,DB0021310017412_,0.545758279,0.18581011,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,pantoprazole,DB00213
,249693,DB00635,10017412,52,33001,31,23763,0.437119224,1.207845934,0.75950788,1.950355384,0.605628379,DB0063510017412_,0.501488717,0.188838554,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,prednisone,DB00635
,249699,DB06724,10017412,42,7887,9,3910,0.017116308,2.313373326,1.108523791,5.410501552,0.054676083,DB0672410017412_,2.906328902,0.838706774,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,calcium carbonate,DB06724
,249701,DB14500,10017412,39,7770,20,4053,1,1.01716105,0.578095062,1.843267129,1,DB1450010017412_,0,0.017015462,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,potassium,DB14500
,249759,DB00374,10023232,101,17615,27,5697,0.41079696,1.209806865,0.783734504,1.92694153,0.580143351,DB0037410023232_,0.544480049,0.190460731,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,249761,DB08931,10023232,126,6451,40,2406,0.427799756,1.17481484,0.81446243,1.726966042,0.596354496,DB0893110023232_,0.516919997,0.161110552,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,riociguat,DB08931
,249768,DB00722,10048908,58,25345,34,25998,0.009015733,1.749802643,1.126253818,2.757322054,0.032765786,DB0072210048908_,3.418370415,0.559503006,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,lisinopril,DB00722
,249791,DB00115,10061309,72,18353,22,10450,0.009609855,1.863417662,1.14158109,3.157203999,0.034486317,DB0011510061309_,3.367192632,0.622412254,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyanocobalamin,DB00115
,249793,DB00722,10061309,63,25340,50,25982,0.187815832,1.291912315,0.876783108,1.912551324,0.333856708,DB0072210061309_,1.097043396,0.256123535,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lisinopril,DB00722
,249794,DB06643,10061309,142,52279,16,7499,0.401578754,1.273042037,0.75682954,2.289148901,0.571339515,DB0664310061309_,0.559771648,0.241409341,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,denosumab,DB06643
,249838,DB00213,10056812,40,18855,19,13402,0.185572228,1.49638668,0.846210245,2.736790847,0.330909129,DB0021310056812_,1.105911476,0.403053322,NA,10056812,Body height decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,249841,DB00641,10056812,45,14079,21,12454,0.018280924,1.89547839,1.105220806,3.351739762,0.057543151,DB0064110056812_,2.855220158,0.639471255,NA,10056812,Body height decreased,10022891,Investigations,Inv,simvastatin,DB00641
,249842,DB00722,10056812,66,25337,35,25997,0.001364804,1.934798124,1.265042768,3.004980812,0.007115714,DB0072210056812_,4.945449689,0.660002992,NA,10056812,Body height decreased,10022891,Investigations,Inv,lisinopril,DB00722
,249853,DB01296,10033371,65,1384,20,963,0.001039909,2.260678466,1.341287825,3.968089502,0.005692804,DB0129610033371_,5.168552385,0.815664975,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,glucosamine,DB01296
,249938,DB00820,10038683,44,11871,10,5806,0.028504363,2.151920598,1.066044173,4.799445068,0.081385747,DB0082010038683_,2.508555119,0.766360745,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,249993,DB00537,10043248,38,7519,27,4271,0.368546315,0.79947521,0.474713356,1.363689149,0.53828466,DB0053710043248_,0.61936775,-0.223799755,NA,10043248,Tendon rupture,10022117,"Injury, poisoning and procedural complications",Inj&P,ciprofloxacin,DB00537
,250036,DB00091,10000087,47,5463,11,2659,0.024670371,2.079499439,1.060861333,4.453530511,0.0727847,DB0009110000087_,2.620249516,0.73212721,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,cyclosporine,DB00091
,250038,DB00697,10000087,73,6023,9,1797,0.007917987,2.419883904,1.204073255,5.513096239,0.029544225,DB0069710000087_,3.521866984,0.883719565,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,tizanidine,DB00697
,250079,DB00768,10013968,44,1871,18,666,0.661512283,0.870186765,0.488580332,1.611977983,0.793530958,DB0076810013968_,0.231262725,-0.139047418,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,olopatadine,DB00768
,250107,DB00091,10028411,61,5449,15,2655,0.018822823,1.981319958,1.110004345,3.760676539,0.05891027,DB0009110028411_,2.831739844,0.683763268,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclosporine,DB00091
,250115,DB00768,10028813,79,1836,12,672,0.003348847,2.408933186,1.29428501,4.890303352,0.014780361,DB0076810028813_,4.214455908,0.879183988,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,olopatadine,DB00768
,250158,DB01050,10037855,46,18062,19,9352,0.435216687,1.25349937,0.719656997,2.266897546,0.603657715,DB0105010037855_,0.504747939,0.225939136,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,ibuprofen,DB01050
,250171,DB00697,10039101,46,6050,8,1798,0.193237064,1.708696081,0.796690362,4.199859405,0.340705408,DB0069710039101_,1.076737082,0.535730554,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tizanidine,DB00697
,250189,DB00564,10046735,32,2572,21,1442,0.567814846,0.854369126,0.475670049,1.56528994,0.718862019,DB0056410046735_,0.330085847,-0.157391946,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,carbamazepine,DB00564
,250190,DB00697,10046735,67,6029,17,1789,0.694969157,1.169450592,0.676788579,2.13040667,0.816414047,DB0069710046735_,0.202833642,0.156534059,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,tizanidine,DB00697
,250209,DB00697,10070863,136,5960,49,1757,0.249121049,0.818229991,0.583438494,1.163897826,0.40850599,DB0069710070863_,0.895248702,-0.200611819,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,tizanidine,DB00697
,250347,DB06643,10016825,48,52373,13,7502,0.050428879,0.528921803,0.281883979,1.064641463,0.12580164,DB0664310016825_,2.073048897,-0.636914678,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,denosumab,DB06643
,250353,DB01137,10048959,103,7669,58,5535,0.147878327,1.281681087,0.918367799,1.803605931,0.281044201,DB0113710048959_,1.269243324,0.248172566,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,250377,DB00275,10016322,44,2016,17,1220,0.141598192,1.566092689,0.872297782,2.937443312,0.272009682,DB0027510016322_,1.301917619,0.448583784,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,olmesartan,DB00275
,250399,DB00404,10027417,50,19842,34,9828,0.163948622,0.72838347,0.461533015,1.162289957,0.3027107,DB0040410027417_,1.194977717,-0.316927625,NA,10027417,Metabolic acidosis,10027433,Metabolism and nutrition disorders,Metab,alprazolam,DB00404
,250437,DB00321,10013496,44,7403,11,2839,0.228869674,1.533980095,0.778179481,3.29816742,0.384533822,DB0032110013496_,0.95572353,0.427865727,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,amitriptyline,DB00321
,250486,DB00321,10076309,49,7398,24,2826,0.357684976,0.779912937,0.46840459,1.331741796,0.527373418,DB0032110076309_,0.639846409,-0.248572984,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,amitriptyline,DB00321
,250487,DB00335,10076309,74,8392,29,5436,0.025359285,1.652846359,1.060895779,2.638023321,0.0742902,DB0033510076309_,2.599776236,0.502498868,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,atenolol,DB00335
,250489,DB14513,10076309,49,7128,21,3543,0.612696997,1.159764782,0.681404166,2.039389318,0.754550124,DB1451310076309_,0.281633569,0.14821721,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium,DB14513
,250505,DB01162,10003549,11,262,72,1630,1,0.950501985,0.448227247,1.834707018,1,DB0116210003549_,0,-0.050765029,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,terazosin,DB01162
,250508,DB00480,10012374,37,67391,26,67636,0.167846758,1.428240193,0.841771779,2.456746311,0.30793551,DB0048010012374_,1.177864901,0.356443052,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,250522,DB01234,10013990,66,31559,63,32825,0.659817581,1.089626506,0.759451535,1.564682501,0.792221136,DB0123410013990_,0.232914713,0.085834983,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,dexamethasone,DB01234
,250596,DB00065,10019974,65,9399,47,4910,0.090528611,0.722449289,0.487973437,1.076778949,0.196089374,DB0006510019974_,1.629184736,-0.32510805,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,infliximab,DB00065
,250599,DB00814,10019974,47,8240,15,3400,0.48366241,1.29282528,0.709137758,2.492745997,0.647931626,DB0081410019974_,0.433970103,0.256829963,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,meloxicam,DB00814
,250685,DB00158,10007515,47,16768,50,8054,0.000119035,0.451508885,0.296352073,0.686894219,0.000925144,DB0015810007515_,6.98556136,-0.795160227,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,folic acid,DB00158
,250690,DB01611,10007515,68,11845,13,2348,1,1.036883754,0.566583512,2.049680589,1,DB0161110007515_,0,0.036219825,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,hydroxychloroquine,DB01611
,250782,DB01373,10001551,57,22663,14,7367,0.408169128,1.323463102,0.727619012,2.573508987,0.57758953,DB0137310001551_,0.548891818,0.280251863,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,calcium,DB01373
,250787,DB01373,10003481,58,22662,16,7365,0.684790222,1.17809163,0.667650411,2.197056372,0.809622937,DB0137310003481_,0.21118665,0.163895867,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,calcium,DB01373
,250852,DB01097,10028411,44,6221,7,1496,0.375958175,1.511480679,0.673619949,3.985504566,0.545744064,DB0109710028411_,0.605605161,0.413089752,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,250854,DB01097,10037153,84,6181,24,1479,0.461387361,0.837534292,0.524608117,1.383967724,0.628664915,DB0109710037153_,0.46415689,-0.17729307,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,leflunomide,DB01097
,250937,DB00973,10037153,32,3819,26,2995,0.895163545,0.965203912,0.555923553,1.690316579,0.956064085,DB0097310037153_,0.044930333,-0.035415892,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,ezetimibe,DB00973
,250968,DB01164,10045458,23,6501,40,7896,0.20430897,0.698403092,0.398731493,1.196520898,0.354262239,DB0116410045458_,1.037717853,-0.358958846,NA,10045458,Umbilical hernia,10017947,Gastrointestinal disorders,Gastr,calcium chloride,DB01164
,250980,DB00540,10003988,46,2437,22,1069,0.790440191,0.917211334,0.537540959,1.609538558,0.886473405,DB0054010003988_,0.120504154,-0.086417371,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,nortriptyline,DB00540
,251015,DB00482,10028391,55,8204,17,3054,0.595083857,1.20433537,0.687301956,2.217085608,0.740772379,DB0048210028391_,0.300061881,0.185927855,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,251030,DB00973,10006451,59,3792,12,3009,1.63163361035718e-06,3.900731453,2.069994703,7.989109044,2.21870095438379e-05,DB0097310006451_,10.7160036,1.361164088,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,ezetimibe,DB00973
,251031,DB01225,10006451,33,5011,26,4614,0.602254763,1.168655545,0.67671741,2.038104102,0.746309613,DB0122510006451_,0.292614734,0.155853981,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,enoxaparin,DB01225
,251043,DB08932,10003522,47,19396,22,6575,0.213397884,0.724210238,0.427490013,1.262957249,0.365501149,DB0893210003522_,1.006485857,-0.322673544,NA,10003522,Aspiration pleural cavity,10022891,Investigations,Inv,macitentan,DB08932
,251061,DB00051,10070325,37,25694,29,11391,0.023182446,0.565664353,0.338333869,0.954096811,0.06931922,DB0005110070325_,2.669033069,-0.569754393,NA,10070325,Mycobacterium tuberculosis complex test positive,10022891,Investigations,Inv,adalimumab,DB00051
,251089,DB00989,10013709,68,766,77,801,0.664958631,0.923533186,0.646332261,1.31726919,0.79606657,DB0098910013709_,0.228072466,-0.079548545,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,rivastigmine,DB00989
,251091,DB00190,10027175,66,3231,74,4600,0.166661879,1.269742622,0.894264621,1.799750891,0.30632176,DB0019010027175_,1.183119227,0.23881422,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,251093,DB00190,10049438,17,3280,37,4637,0.165588536,0.64958119,0.34236527,1.185210445,0.304935346,DB0019010049438_,1.187655505,-0.431427447,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,251130,DB00563,10039580,43,46603,8,15340,0.146480055,1.76916189,0.822012271,4.357986255,0.279012155,DB0056310039580_,1.276499931,0.570505926,NA,10039580,Scar,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,251146,DB00310,10013573,37,907,32,749,0.901993699,0.954832807,0.572545755,1.600127947,0.957184982,DB0031010013573_,0.043758612,-0.046219025,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,chlorthalidone,DB00310
,251152,DB00310,10019211,39,905,18,763,0.04173245,1.826090384,1.010345211,3.420782777,0.109191463,DB0031010019211_,2.214652392,0.602177279,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,chlorthalidone,DB00310
,251153,DB08907,10019211,63,4190,44,3866,0.17294906,1.321052379,0.882344822,1.993382825,0.314719516,DB0890710019211_,1.156073463,0.278428676,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,canagliflozin,DB08907
,251160,DB00697,10042674,66,6030,11,1795,0.076459533,1.785899768,0.933585147,3.758565963,0.172265574,DB0069710042674_,1.75871796,0.57992236,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,tizanidine,DB00697
,251208,DB01115,10044565,38,3562,14,2254,0.087098041,1.71742562,0.907158886,3.439435953,0.190234077,DB0111510044565_,1.659499979,0.540826437,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,nifedipine,DB01115
,251275,DB01024,10010264,51,2160,33,2087,0.078307607,1.493080608,0.940857145,2.398785118,0.17555678,DB0102410010264_,1.739792758,0.400841507,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,mycophenolic acid,DB01024
,251277,DB14513,10010264,141,7036,30,3534,5.48305017793221e-06,2.360527884,1.579040054,3.635424401,6.40969419288184e-05,DB1451310010264_,9.655113903,0.858885274,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,251305,DB00203,10051099,93,13785,25,8913,3.98345963388307e-05,2.405157083,1.531408555,3.908081924,0.000363245,DB0020310051099_,7.920434307,0.877615217,NA,10051099,Catheter site haemorrhage,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,251408,DB00065,10017944,37,9427,16,4941,0.565290324,1.212011835,0.657074933,2.336065497,0.716865154,DB0006510017944_,0.332867525,0.192281653,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,infliximab,DB00065
,251580,DB13961,10040979,34,9423,30,6384,0.308574061,0.767846436,0.455518822,1.300340403,0.475920153,DB1396110040979_,0.742505186,-0.264165518,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fish oil,DB13961
,251623,DB01050,10020993,16,18092,35,9336,7.16241082865617e-07,0.235913213,0.121843626,0.437901508,1.0654440782752e-05,DB0105010020993_,11.44953378,-1.444291282,male,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,ibuprofen,DB01050
,251648,DB01050,10047461,63,18045,22,9349,0.135675991,1.483611805,0.899743137,2.533977951,0.263653022,DB0105010047461_,1.333121351,0.394479524,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,251730,DB00480,10037876,44,67384,58,67604,0.197689131,0.761101302,0.502313062,1.14602,0.346186464,DB0048010037876_,1.060777737,-0.272988813,NA,10037876,Rash papular,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,251779,DB00003,10010774,45,2953,28,2565,0.193791563,1.395892517,0.849224618,2.330938092,0.341454031,DB0000310010774_,1.074542217,0.333534008,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,dornase alfa,DB00003
,251785,DB11065,10010774,84,3102,47,2641,0.026256106,1.521516306,1.048017066,2.231804902,0.076334668,DB1106510010774_,2.572628073,0.419707407,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,pancrelipase amylase,DB11065
,251796,DB11065,10013968,111,3075,101,2587,0.575302256,0.924613834,0.696023226,1.229400399,0.724761996,DB1106510013968_,0.32191196,-0.078379106,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pancrelipase amylase,DB11065
,251801,DB09153,10018964,55,7744,45,5654,0.611776503,0.892370044,0.589878605,1.356240806,0.753805011,DB0915310018964_,0.282621551,-0.113874385,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,251840,DB01373,10052251,34,22686,17,7364,0.144627803,0.649221595,0.352532148,1.239924666,0.276495877,DB0137310052251_,1.285559371,-0.43198118,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,251856,DB00601,10013709,30,875,49,862,0.037853509,0.603318531,0.366014915,0.980061862,0.101357866,DB0060110013709_,2.289097798,-0.505309978,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,linezolid,DB00601
,251857,DB00760,10013709,42,738,115,900,7.04468487976592e-06,0.445594092,0.30105242,0.649074218,7.98660953481334e-05,DB0076010013709_,9.435159134,-0.80834685,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,meropenem,DB00760
,251895,DB00531,10040070,95,7157,100,6416,0.278961156,0.851653124,0.634941428,1.141690101,0.442812459,DB0053110040070_,0.814608941,-0.160575966,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,251898,DB00158,10069339,154,16661,135,7969,5.02693930774553e-07,0.545606738,0.429532877,0.693754643,7.79086672783556e-06,DB0015810069339_,11.76255844,-0.605856824,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,folic acid,DB00158
,251945,DB05259,10005750,48,11222,10,2718,0.742533649,1.162560763,0.579811,2.580622794,0.852497192,DB0525910005750_,0.159585364,0.150625126,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,glatiramer,DB05259
,251985,DB01224,10069339,105,8003,75,5842,0.939495565,1.021966766,0.751133081,1.396198585,0.978955459,DB0122410069339_,0.021269134,0.021728972,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,quetiapine,DB01224
,251988,DB01068,10040108,43,13720,50,6790,5.47484781463178e-05,0.425627211,0.276105092,0.653685654,0.000477222,DB0106810040108_,7.647528206,-0.854191408,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,clonazepam,DB01068
,252158,DB01069,10006451,101,6599,15,2380,0.000617513,2.428114282,1.401101899,4.507749569,0.003688522,DB0106910006451_,5.602529529,0.88711494,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,promethazine,DB01069
,252168,DB00395,10007617,56,2128,27,709,0.124402645,0.691128087,0.425536081,1.147409842,0.247683952,DB0039510007617_,1.395601734,-0.369430107,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,carisoprodol,DB00395
,252171,DB00697,10007617,53,6043,29,1777,0.01125896,0.537485288,0.334449333,0.87956535,0.039126321,DB0069710007617_,3.24095988,-0.62085389,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,tizanidine,DB00697
,252174,DB01069,10007617,48,6652,23,2372,0.278427,0.744202209,0.442784394,1.28485624,0.442236393,DB0106910007617_,0.815910714,-0.295442494,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,promethazine,DB01069
,252175,DB01142,10007617,77,1663,31,753,0.670918928,1.124630185,0.725069687,1.782189887,0.80035872,DB0114210007617_,0.222695252,0.117454257,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,doxepin,DB01142
,252263,DB00588,10039906,119,16405,71,8397,0.317567988,0.857913378,0.633329256,1.169331389,0.485433663,DB0058810039906_,0.722712636,-0.153252143,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,252281,DB00814,10043071,43,8244,14,3401,0.559060853,1.267047867,0.67887757,2.510974784,0.711840552,DB0081410043071_,0.339901337,0.236689681,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,meloxicam,DB00814
,252348,DB00471,10069339,128,14061,54,5411,0.561597907,0.912182884,0.657619118,1.280209274,0.713983118,DB0047110069339_,0.336895961,-0.091914778,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,montelukast,DB00471
,252350,DB00697,10069339,69,6027,28,1778,0.179798878,0.727010644,0.460708594,1.175667756,0.323632971,DB0069710069339_,1.128145212,-0.31881416,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,tizanidine,DB00697
,252351,DB00959,10069339,170,7908,160,4842,0.0001454,0.650605571,0.519547215,0.814981632,0.001097759,DB0095910069339_,6.814484127,-0.429851702,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,methylprednisolone,DB00959
,252352,DB01069,10069339,105,6595,73,2322,2.09997497163191e-05,0.506444326,0.370649164,0.695143586,0.000208215,DB0106910069339_,8.476938532,-0.68034088,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,promethazine,DB01069
,252590,DB00497,10005395,33,19234,24,16351,0.596689625,1.168894487,0.669910176,2.067787219,0.742050851,DB0049710005395_,0.298337506,0.156058419,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,oxycodone,DB00497
,252655,DB00264,10021425,31,29576,20,24872,0.400103662,1.30346781,0.719468241,2.413592075,0.569981289,DB0026410021425_,0.562151745,0.265028259,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,metoprolol,DB00264
,252758,DB00334,10054112,25,2824,36,2776,0.157435825,0.682690204,0.391696272,1.172632587,0.294104734,DB0033410054112_,1.223819338,-0.381714103,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,olanzapine,DB00334
,252759,DB01224,10054112,58,8050,60,5857,0.061134395,0.703354344,0.480875634,1.028048543,0.14552747,DB0122410054112_,1.927390416,-0.351894469,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,quetiapine,DB01224
,252768,DB09037,10019211,43,2483,44,2791,0.666779149,1.098477265,0.701848154,1.718165097,0.797428848,DB0903710019211_,0.226362667,0.093924917,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pembrolizumab,DB09037
,252770,DB00973,10005557,31,3820,34,2987,0.20898258,0.712986574,0.422694509,1.198577043,0.360038482,DB0097310005557_,1.021544358,-0.338292688,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,ezetimibe,DB00973
,252776,DB01373,10001497,35,22685,24,7357,0.005989746,0.472955231,0.27324895,0.831681836,0.023634388,DB0137310001497_,3.745052509,-0.748754545,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,calcium,DB01373
,252796,DB06643,10013952,91,52330,13,7502,1,1.003516114,0.558147508,1.957614518,1,DB0664310013952_,0,0.003509947,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,denosumab,DB06643
,252877,DB00480,10001053,45,67383,52,67610,0.542523728,0.868301485,0.569287574,1.319824165,0.697734634,DB0048010001053_,0.359916429,-0.141216291,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,252878,DB00512,10001053,44,4693,45,5053,0.831844343,1.052800838,0.67739722,1.635228276,0.912164058,DB0051210001053_,0.091935417,0.051454077,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vancomycin,DB00512
,252892,DB06724,10001053,34,7895,21,3898,0.472680786,0.799408588,0.450105773,1.451501829,0.638672447,DB0672410001053_,0.448363558,-0.22388309,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium carbonate,DB06724
,252902,DB04861,10002034,36,1929,20,1367,0.414564106,1.275492095,0.715259163,2.336216315,0.583778931,DB0486110002034_,0.538232911,0.243332061,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,nebivolol,DB04861
,252991,DB00661,10069339,32,3496,41,1554,9.5264906671318e-06,0.347013447,0.210649523,0.567071836,0.00010427,DB0066110069339_,9.168529257,-1.058391748,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,verapamil,DB00661
,253179,DB00455,10043882,34,9367,17,5101,0.883544594,1.08914495,0.591136643,2.080915925,0.951303696,DB0045510043882_,0.049921923,0.085392939,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,loratadine,DB00455
,253198,DB08907,10003988,32,4221,38,3872,0.336525261,0.772506018,0.466203716,1.272660071,0.505562054,DB0890710003988_,0.682084491,-0.25811548,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,canagliflozin,DB08907
,253205,DB00115,10017533,63,18362,15,10457,0.001348603,2.391797859,1.345347517,4.525576539,0.007043821,DB0011510017533_,4.955604478,0.872045326,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,253221,DB08907,10033371,43,4210,27,3883,0.120097758,1.468819245,0.885226349,2.47697472,0.241511582,DB0890710033371_,1.420837847,0.384458843,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,canagliflozin,DB08907
,253248,DB00563,10048865,37,46609,16,15332,0.343162005,0.760699078,0.412738758,1.465088041,0.51245708,DB0056310048865_,0.668538318,-0.273517429,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,methotrexate,DB00563
,253294,DB00213,10019196,57,18838,28,13393,0.12274249,1.447287157,0.904878122,2.364626002,0.245326313,DB0021310019196_,1.405166065,0.369690878,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,253321,DB08868,10039906,135,9067,29,2482,0.251799207,1.274276503,0.845802058,1.979747856,0.411869825,DB0886810039906_,0.887047938,0.242378569,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,253355,DB00864,10043645,100,6769,102,8290,0.200674278,1.2006688,0.900274626,1.600910408,0.349782719,DB0086410043645_,1.050443121,0.182878735,NA,10043645,Thrombotic microangiopathy,10005329,Blood and lymphatic system disorders,Blood,tacrolimus,DB00864
,253482,DB00451,10002953,47,47224,12,15407,0.545633351,1.277812279,0.667208443,2.647063218,0.700377128,DB0045110002953_,0.356136335,0.245149459,NA,10002953,Aphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,253495,DB00996,10021654,37,38916,16,22409,0.392974138,1.331600802,0.722566303,2.564517966,0.562967365,DB0099610021654_,0.574533618,0.286381829,NA,10021654,Increased appetite,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,253521,DB00497,10029216,54,19213,30,16345,0.062804969,1.531285093,0.962039808,2.480095696,0.148663029,DB0049710029216_,1.906073087,0.426107313,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,253586,DB00722,10020765,49,25354,47,25985,0.760213357,1.068531483,0.701057076,1.630142734,0.866700271,DB0072210020765_,0.143062071,0.06628526,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,253589,DB01076,10020765,43,25704,40,25543,0.826338712,1.068295585,0.677966139,1.686673504,0.908343636,DB0107610020765_,0.096132518,0.066064468,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,253591,DB00203,10022086,40,13838,24,8914,0.898088324,1.07362072,0.631104639,1.863226924,0.956338178,DB0020310022086_,0.044643686,0.071036786,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,253596,DB00203,10043417,15,13863,36,8902,8.3198840489947e-06,0.267575778,0.136023907,0.501407427,9.25860085638551e-05,DB0020310043417_,9.287372523,-1.318352472,male,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,253597,DB00338,10043417,66,33608,35,22237,0.310216745,1.247678535,0.815815183,1.937935756,0.477637393,DB0033810043417_,0.738903427,0.221284653,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,253603,DB01076,10043417,50,25697,39,25544,0.288896726,1.27440889,0.821345638,1.990198124,0.453975636,DB0107610043417_,0.789711749,0.242482455,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,253780,DB06605,10054112,325,13748,207,12826,2.03184247897997e-05,1.46472804,1.224514492,1.755206728,0.000202453,DB0660510054112_,8.505005078,0.381669587,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,apixaban,DB06605
,253795,DB06605,10044565,96,13977,67,12966,0.083441507,1.329177341,0.961926308,1.845754765,0.184160546,DB0660510044565_,1.691947369,0.28456021,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,253797,DB00213,10008111,33,18862,28,13393,0.516798184,0.836855697,0.490084407,1.438193346,0.676445498,DB0021310008111_,0.3909034,-0.178103628,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,253803,DB00497,10056819,61,19206,40,16335,0.230212484,1.297024975,0.855948259,1.984816217,0.386172829,DB0049710056819_,0.951470266,0.260073161,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,253813,DB06605,10019303,122,13951,62,12971,8.13141258951135e-05,1.829468618,1.335514526,2.528099184,0.000668442,DB0660510019303_,7.310561626,0.604025552,NA,10019303,Heart rate increased,10022891,Investigations,Inv,apixaban,DB06605
,253877,DB06186,10069339,55,2154,128,3518,0.030068561,0.701823728,0.499727721,0.974744979,0.08484725,DB0618610069339_,2.466902694,-0.354073006,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ipilimumab,DB06186
,253913,DB00727,10051055,22,3821,32,4141,0.339121618,0.745105413,0.41171167,1.325435437,0.50821356,DB0072710051055_,0.676853526,-0.294229576,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,nitroglycerin,DB00727
,253941,DB00563,10064687,39,46607,25,15323,0.012837739,0.512859849,0.302555137,0.884563515,0.043453733,DB0056310064687_,3.13605851,-0.667752669,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,254015,DB00635,10041541,35,33018,24,23770,0.895636384,1.04987537,0.60681223,1.845325898,0.95615204,DB0063510041541_,0.044838341,0.048671462,NA,10041541,Spinal compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,254072,DB00888,10003051,66,611,65,700,0.410593277,1.163163868,0.798686232,1.694437722,0.580005068,DB0088810003051_,0.544718438,0.151143765,NA,10003051,Application site pain,10018065,General disorders and administration site conditions,Genrl,mechlorethamine,DB00888
,254135,DB01238,10054112,95,5155,123,3379,7.98806023697705e-07,0.50629611,0.381836403,0.669618929,1.17529338555243e-05,DB0123810054112_,11.35140766,-0.680633584,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,aripiprazole,DB01238
,254276,DB00437,10036790,35,6886,45,11501,0.248963675,1.299000785,0.809742998,2.068590331,0.408388055,DB0043710036790_,0.895537441,0.261595342,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,allopurinol,DB00437
,254306,DB00313,10044565,35,1204,22,1495,0.01484149,1.974906538,1.119734278,3.554313357,0.048898041,DB0031310044565_,3.018017942,0.680521075,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,valproic acid,DB00313
,254363,DB00524,10037423,48,1529,26,1318,0.059450117,1.591136544,0.961465168,2.687917233,0.142479013,DB0052410037423_,1.948560569,0.464448569,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metolazone,DB00524
,254375,DB00051,10011781,64,25667,8,11412,0.000159481,3.556483519,1.699954508,8.592270807,0.001189044,DB0005110011781_,6.7346054,1.268772281,female,10011781,Cystitis,10021881,Infections and infestations,Infec,adalimumab,DB00051
,254379,DB00051,10023424,41,25690,14,11406,0.465748934,1.300197932,0.694019682,2.583556739,0.632541632,DB0005110023424_,0.45800924,0.262516508,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,adalimumab,DB00051
,254674,DB00295,10039906,94,14569,63,9539,0.934779737,0.976913909,0.701737563,1.36789015,0.975176325,DB0029510039906_,0.025136978,-0.023356748,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,morphine,DB00295
,254754,DB01068,10069326,71,13692,34,6806,0.917464491,1.038001147,0.679697252,1.613286389,0.963349796,DB0106810069326_,0.037338698,0.037296889,NA,10069326,Product substitution issue,10077536,Product issues,Prod,clonazepam,DB01068
,254819,DB01012,10061024,37,10595,31,8654,1,0.974884539,0.587970915,1.626426068,1,DB0101210061024_,0,-0.025436237,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,cinacalcet,DB01012
,254883,DB00668,10069868,40,10051,18,4285,0.885864392,0.947395043,0.530059578,1.757714407,0.952535694,DB0066810069868_,0.048627699,-0.05403912,NA,10069868,Device issue,10077536,Product issues,Prod,epinephrine,DB00668
,254885,DB06404,10069868,55,3014,11,889,0.299192534,1.474629654,0.759287574,3.138519622,0.465204126,DB0640410069868_,0.765278989,0.388406876,NA,10069868,Device issue,10077536,Product issues,Prod,human c1-esterase inhibitor,DB06404
,254916,DB00051,10038063,76,25655,43,11377,0.197539114,0.783768108,0.531954748,1.168142658,0.346030151,DB0005110038063_,1.061229367,-0.243642082,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,254961,DB01020,10008479,70,1743,74,1804,0.932354773,0.979053762,0.691051276,1.38594698,0.973154319,DB0102010008479_,0.027212608,-0.021168723,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,isosorbide mononitrate,DB01020
,255022,DB00829,10012373,42,8010,16,4438,0.218516685,1.454359562,0.79960371,2.774409352,0.371725144,DB0082910012373_,0.989600559,0.37456564,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,255023,DB00924,10012373,23,10139,32,4219,9.92183863202124e-06,0.299115901,0.166896118,0.528092678,0.000107856,DB0092410012373_,9.134714626,-1.206924152,male,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,255074,DB00297,10028372,34,1638,31,848,0.02501851,0.567915483,0.33609028,0.962812208,0.073503405,DB0029710028372_,2.610423548,-0.565782668,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,bupivacaine,DB00297
,255091,DB08868,10028391,60,9142,21,2490,0.341103835,0.778215987,0.465494278,1.349779382,0.510285224,DB0886810028391_,0.672785447,-0.250751174,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fingolimod,DB08868
,255121,DB08868,10036018,47,9155,21,2490,0.073634349,0.608752717,0.356026162,1.07424681,0.167566673,DB0886810036018_,1.78637396,-0.496343142,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,fingolimod,DB08868
,255167,DB14500,10050584,97,7712,23,4050,0.000316481,2.214657869,1.39176324,3.663387521,0.002108133,DB1450010050584_,6.161952322,0.795097931,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium,DB14500
,255169,DB00169,10058920,105,38586,20,18155,6.98459810213333e-05,2.470130879,1.52057061,4.209326952,0.000585988,DB0016910058920_,7.442210589,0.904271137,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,255223,DB00727,10021789,30,3813,25,4148,0.345445089,1.305379882,0.740622519,2.319378914,0.514871944,DB0072710021789_,0.663837061,0.266494096,NA,10021789,Infection,10021881,Infections and infestations,Infec,nitroglycerin,DB00727
,255233,DB00175,10028391,44,8087,28,6078,0.551270089,1.181025833,0.718089357,1.972420455,0.705339124,DB0017510028391_,0.349076565,0.16638341,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,255252,DB06655,10012378,34,3654,24,2095,0.493316927,0.812278823,0.466289539,1.43589383,0.656033768,DB0665510012378_,0.421543016,-0.20791162,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,liraglutide,DB06655
,255276,DB00285,10018100,45,10906,9,3709,0.159970429,1.700308324,0.819811259,3.960306727,0.297423359,DB0028510018100_,1.212598704,0.530809602,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,255312,DB00285,10045555,55,10896,18,3700,1,1.037607628,0.599069772,1.880155236,1,DB0028510045555_,0,0.036917706,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,255327,DB00697,10074903,59,6037,7,1799,0.017513494,2.511543046,1.142974622,6.529932861,0.055691053,DB0069710074903_,2.887935776,0.920897324,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,tizanidine,DB00697
,255332,DB00683,10010264,27,1557,33,1605,0.602491374,0.843450508,0.485350202,1.454120535,0.746387924,DB0068310010264_,0.292509809,-0.170254053,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,midazolam,DB00683
,255345,DB09020,10010305,45,1909,40,1564,0.741331418,0.921708339,0.585227273,1.456268869,0.851637697,DB0902010010305_,0.160594081,-0.08152644,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,bisacodyl,DB09020
,255377,DB11365,10069339,41,1604,51,1497,0.203909184,0.750364422,0.481862149,1.162129253,0.353674017,DB1136510069339_,1.039379646,-0.287196295,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,sennosides,DB11365
,255388,DB11097,10011906,31,823,37,646,0.104488621,0.657838406,0.390003874,1.102941598,0.217732948,DB1109710011906_,1.524485974,-0.418795961,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,plantago seed,DB11097
,255393,DB00316,10067268,41,65433,21,36932,0.792043875,1.101982902,0.636189632,1.963200233,0.887420002,DB0031610067268_,0.1194369,0.097111195,NA,10067268,Post procedural infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,255495,DB00783,10076309,247,16467,12,361,0.014914778,0.451256175,0.25066437,0.893628695,0.04909335,DB0078310076309_,3.014031699,-0.795720085,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,estradiol,DB00783
,255524,DB00051,10040882,56,25675,36,11384,0.089508405,0.689718207,0.445523117,1.08002733,0.194473241,DB0005110040882_,1.637460705,-0.371472161,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,255629,DB00213,10048302,68,18827,52,13369,0.710948372,0.928591281,0.637206591,1.360120886,0.82765808,DB0021310048302_,0.189155157,-0.074086593,NA,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,255645,DB01234,10019465,30,31595,34,32854,0.802806143,0.9175367,0.542269083,1.5452212,0.893313651,DB0123410019465_,0.112817527,-0.0860627,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,255753,DB00773,10043071,36,2287,38,2789,0.557844393,1.155282586,0.709052861,1.879132147,0.710901105,DB0077310043071_,0.341221952,0.144344977,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,etoposide,DB00773
,255785,DB00264,10038678,44,29563,13,24879,0.000457539,2.848170956,1.506277415,5.76459238,0.002868036,DB0026410038678_,5.854127903,1.046677018,female,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,255797,DB05676,10010774,263,46866,102,25227,0.004942364,1.387910291,1.099563428,1.762993831,0.020287351,DB0567610010774_,3.897757701,0.327799228,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,255824,DB05676,10023003,65,47064,31,25298,0.66854858,1.127055129,0.723867468,1.78952279,0.798582115,DB0567610023003_,0.22491748,0.119608151,NA,10023003,Irritable bowel syndrome,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,255834,DB00537,10076309,48,7509,47,4251,0.009736863,0.578223873,0.377848129,0.885214832,0.034842014,DB0053710076309_,3.35693132,-0.547794162,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ciprofloxacin,DB00537
,255863,DB14513,10069339,55,7122,41,3523,0.050196525,0.663584442,0.433888023,1.022111626,0.125383984,DB1451310069339_,2.076374375,-0.410099166,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,magnesium,DB14513
,255905,DB01115,10017577,48,3552,22,2246,0.266224131,1.379534033,0.814237205,2.40671453,0.428360754,DB0111510017577_,0.847789555,0.321745785,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,255909,DB00193,10039117,34,19286,23,8679,0.151096513,0.665247724,0.380332968,1.183551385,0.285408631,DB0019310039117_,1.253833331,-0.407595791,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,255919,DB00480,10031282,81,67347,40,67622,0.000174597,2.033247018,1.375533273,3.049093715,0.001286054,DB0048010031282_,6.656176579,0.709634031,NA,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,255950,DB00480,10062189,105,67323,79,67583,0.05511741,1.334239563,0.986784149,1.810192324,0.134541021,DB0048010062189_,2.005886137,0.288361514,NA,10062189,Vitamin D decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,255951,DB01234,10062189,43,31582,35,32853,0.308436871,1.278005956,0.798743319,2.057629902,0.475736476,DB0123410062189_,0.742891201,0.245301017,NA,10062189,Vitamin D decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,255983,DB00787,10005750,101,16899,63,17185,0.002218641,1.630273246,1.177637024,2.271801281,0.010587687,DB0078710005750_,4.54806352,0.488747636,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,acyclovir,DB00787
,256000,DB00338,10012239,20,33654,36,22236,0.000296938,0.36707441,0.201286796,0.651522202,0.002000728,DB0033810012239_,6.214244342,-1.002190699,male,10012239,Delusion,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,256013,DB00126,10019063,39,10132,35,5910,0.07004968,0.650009211,0.400708981,1.058005696,0.161342751,DB0012610019063_,1.824224288,-0.430768745,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,ascorbic acid,DB00126
,256023,DB00787,10019063,36,16964,21,17227,0.046477984,1.74082384,0.988745292,3.139973439,0.118459596,DB0078710019063_,2.133183342,0.554358472,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,acyclovir,DB00787
,256034,DB00338,10028347,35,33639,23,22249,1,1.006485731,0.577939484,1.784550584,1,DB0033810028347_,0,0.006464789,NA,10028347,Muscle twitching,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,256061,DB00904,10029350,25,23044,43,14413,4.73931774740587e-05,0.363646125,0.212746846,0.609301303,0.000422067,DB0090410029350_,7.770347356,-1.011574068,male,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,256110,DB00158,10012601,59,16756,31,8073,0.735408281,0.916975203,0.583501061,1.466866604,0.847128718,DB0015810012601_,0.165902626,-0.086674848,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,folic acid,DB00158
,256127,DB00996,10037162,144,38809,35,22390,1.09767451660272e-06,2.373613301,1.630304448,3.541278011,1.55329069549946e-05,DB0099610037162_,11.07254976,0.864413394,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,256134,DB00169,10024774,68,38623,59,18116,0.000779216,0.540575817,0.375624359,0.779962658,0.004475407,DB0016910024774_,5.409158058,-0.61512038,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,256154,DB00722,10024774,48,25355,69,25963,0.078424592,0.712340962,0.482105553,1.045074316,0.175735905,DB0072210024774_,1.73877295,-0.339198603,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,lisinopril,DB00722
,256155,DB00761,10024774,43,15264,24,8601,1,1.009572915,0.598560524,1.74068506,1,DB0076110024774_,0,0.009527385,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,256160,DB00904,10024774,40,23029,28,14428,0.708600246,0.89502533,0.538345099,1.507125499,0.826067099,DB0090410024774_,0.191079275,-0.110903259,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,ondansetron,DB00904
,256164,DB01015,10024774,19,9868,32,9349,0.049509511,0.562543086,0.30103445,1.02390883,0.1240747,DB0101510024774_,2.086871476,-0.57528755,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,256302,DB00814,10012601,37,8250,14,3401,0.877971332,1.089488739,0.574416162,2.184674071,0.948285522,DB0081410012601_,0.053099639,0.085708539,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,meloxicam,DB00814
,256341,DB01281,10003988,102,8830,10,1788,0.022090645,2.065286598,1.075629436,4.445132359,0.066835587,DB0128110003988_,2.705519602,0.725269005,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,abatacept,DB01281
,256342,DB01281,10019974,80,8852,14,1784,0.781120852,1.151621626,0.646130796,2.205971778,0.880828655,DB0128110019974_,0.126892162,0.141171059,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,abatacept,DB01281
,256416,DB01076,10005619,33,25714,21,25562,0.133576996,1.562117538,0.876992014,2.841951569,0.260726346,DB0107610005619_,1.344283905,0.446042297,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,atorvastatin,DB01076
,256434,DB08917,10013573,45,871,11,183,0.717396895,0.859606779,0.427527056,1.879231095,0.833006909,DB0891710013573_,0.182713343,-0.151280228,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ferric carboxymaltose,DB08917
,256505,DB00927,10013911,37,7460,19,4997,0.412704093,1.304396141,0.730148562,2.404163958,0.582107684,DB0092710013911_,0.541099824,0.265740206,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,256508,DB00697,10050584,74,6022,12,1794,0.052149658,1.83691245,0.988521042,3.723621491,0.129060705,DB0069710050584_,2.047472402,0.608086146,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,tizanidine,DB00697
,256525,DB00230,10017918,45,19629,10,8641,0.055646549,1.980930795,0.983609546,4.410463278,0.135444905,DB0023010017918_,1.999190325,0.683566833,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,pregabalin,DB00230
,256553,DB00059,10039906,49,778,31,1076,0.000759116,2.185210531,1.351687619,3.580401304,0.004377659,DB0005910039906_,5.431241131,0.781712177,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,pegaspargase,DB00059
,256570,DB00722,10038669,55,25348,49,25983,0.493242614,1.150563673,0.76822475,1.727553293,0.656001425,DB0072210038669_,0.421592318,0.140251973,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,256589,DB00218,10037660,32,1410,28,922,0.286160333,0.747421414,0.432667799,1.297804991,0.45087513,DB0021810037660_,0.796564851,-0.291126111,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,moxifloxacin,DB00218
,256603,DB09027,10005750,46,5133,51,7101,0.302053342,1.247742011,0.817675367,1.899467299,0.468363985,DB0902710005750_,0.75850954,0.221335526,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,ledipasvir,DB09027
,256607,DB00373,10019211,53,1779,12,1275,0.000106156,3.164363923,1.661085102,6.532983729,0.000839444,DB0037310019211_,7.082771004,1.151952063,female,10019211,Headache,10029205,Nervous system disorders,Nerv,timolol,DB00373
,256616,DB00043,10001760,283,6130,20,2280,4.43309334303502e-19,5.262528894,3.332886486,8.768405759,4.24494930862206e-17,DB0004310001760_,37.6982167,1.660611689,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,omalizumab,DB00043
,256634,DB00198,10037844,65,1210,28,975,0.005523611,1.87008193,1.172907869,3.050960638,0.022152596,DB0019810037844_,3.809800577,0.625982243,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,oseltamivir,DB00198
,256814,DB04951,10011906,303,1579,798,2259,7.94890804837108e-17,0.543285178,0.467307461,0.630588099,5.97817018745162e-15,DB0495110011906_,32.75066186,-0.610120907,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pirfenidone,DB04951
,256825,DB01281,10042609,83,8849,10,1788,0.126713768,1.676994098,0.86553211,3.633135043,0.251066107,DB0128110042609_,1.382039001,0.517002963,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,abatacept,DB01281
,256842,DB01590,10021789,31,4707,23,2844,0.482415607,0.814397105,0.458686355,1.465729517,0.646843021,DB0159010021789_,0.435651639,-0.205307188,NA,10021789,Infection,10021881,Infections and infestations,Infec,everolimus,DB01590
,256860,DB00169,10023003,68,38623,7,18168,5.283040830484e-06,4.569870245,2.101026042,11.79625411,6.20485827655371e-05,DB0016910023003_,9.687592887,1.519484812,female,10023003,Irritable bowel syndrome,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,256908,DB01076,10061422,32,25715,56,25527,0.010270862,0.567260678,0.355350157,0.891535613,0.036339965,DB0107610061422_,3.314837186,-0.566936331,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,256944,DB00230,10062237,36,19638,35,8616,0.001087571,0.451283122,0.275206182,0.740707654,0.005904536,DB0023010062237_,5.132034415,-0.795660372,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,pregabalin,DB00230
,256949,DB05351,10003988,47,2676,22,1109,0.689083578,0.885398306,0.520207911,1.55057099,0.81249806,DB0535110003988_,0.207641753,-0.121717672,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,dexlansoprazole,DB05351
,256951,DB05351,10053762,106,2617,42,1089,0.854120941,1.050207526,0.722519771,1.550430349,0.928957027,DB0535110053762_,0.073692799,0.048987789,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,dexlansoprazole,DB05351
,256981,DB00490,10001497,46,4024,38,1538,0.000802343,0.462733778,0.293307161,0.733953839,0.004586422,DB0049010001497_,5.384655073,-0.770603384,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,buspirone,DB00490
,257027,DB00490,10016322,82,3988,30,1546,0.832255867,1.059601072,0.686530368,1.675193535,0.912520147,DB0049010016322_,0.091545115,0.05789249,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,257068,DB00490,10042458,70,4000,35,1541,0.226965678,0.770525734,0.504155899,1.196809264,0.382127407,DB0049010042458_,0.962001199,-0.260682225,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,buspirone,DB00490
,257073,DB00476,10043431,43,17214,8,6169,0.109924134,1.926276757,0.894535786,4.746748351,0.225981314,DB0047610043431_,1.487302963,0.655588998,NA,10043431,Thinking abnormal,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,257085,DB01156,10047571,81,13541,18,6310,0.003270694,2.096897938,1.245591285,3.717745119,0.014512186,DB0115610047571_,4.232766547,0.74045908,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,bupropion,DB01156
,257165,DB00377,10003988,66,1053,37,686,0.533613222,1.161960342,0.75594877,1.809445699,0.690291035,DB0037710003988_,0.370641981,0.150108529,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,palonosetron,DB00377
,257199,DB00028,10039906,71,13387,53,5562,0.001514184,0.556624967,0.383949508,0.811267464,0.007755138,DB0002810039906_,4.859399641,-0.585863574,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,257269,DB00497,10003553,55,19212,16,16359,6.30379926500706e-05,2.92680768,1.652173967,5.475301486,0.0005371,DB0049710003553_,7.529326178,1.0739123,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,257308,DB01062,10010264,80,4406,10,1735,0.000132106,3.150117261,1.621913629,6.836049229,0.001011036,DB0106210010264_,6.89677942,1.147439678,female,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,257310,DB06655,10010264,42,3646,15,2104,0.128153104,1.615673751,0.875269126,3.14450109,0.253061703,DB0665510010264_,1.374121935,0.479752053,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,liraglutide,DB06655
,257311,DB08893,10010264,37,2048,13,1045,0.292122328,1.452099777,0.750441559,2.99070337,0.45759448,DB0889310010264_,0.781771901,0.373010631,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,mirabegron,DB08893
,257369,DB06655,10016173,34,3654,22,2097,0.677012444,0.886945349,0.502415068,1.596355987,0.804128697,DB0665510016173_,0.217995951,-0.119971911,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,liraglutide,DB06655
,257380,DB08893,10017577,46,2039,30,1028,0.271897395,0.773148344,0.474466537,1.27669452,0.434752203,DB0889310017577_,0.832979059,-0.257284342,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,mirabegron,DB08893
,257401,DB00476,10021143,57,17200,25,6152,0.38187447,0.815482297,0.500804401,1.363576669,0.552000134,DB0047610021143_,0.59420699,-0.203975565,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,257437,DB00471,10028391,59,14130,16,5449,0.245585491,1.42195077,0.806701763,2.649986608,0.404449398,DB0047110028391_,0.905228647,0.352029711,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,257449,DB08893,10035664,54,2031,23,1035,0.542218525,1.196363482,0.717212526,2.054653462,0.697475478,DB0889310035664_,0.360287923,0.179286524,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,mirabegron,DB08893
,257475,DB00575,10047513,41,5203,26,3803,0.620717924,1.15256635,0.687016143,1.96623493,0.761218215,DB0057510047513_,0.272835214,0.141991065,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,clonidine,DB00575
,257481,DB13961,10047513,104,9353,49,6365,0.038188196,1.444357656,1.01731128,2.075388125,0.101978738,DB1396110047513_,2.282990936,0.367664694,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,fish oil,DB13961
,257497,DB01062,10048959,67,4419,26,1719,1,1.002428073,0.626262799,1.648886963,1,DB0106210048959_,0,0.00242513,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,oxybutynin,DB01062
,257549,DB00193,10061224,48,19272,21,8681,1,1.029615978,0.604333915,1.811402481,1,DB0019310061224_,0,0.029185896,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,257551,DB00331,10061224,70,24876,34,20718,0.010093309,1.714669154,1.122339229,2.665700851,0.035844439,DB0033110061224_,3.328566839,0.539220149,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,metformin,DB00331
,257558,DB00678,10061224,62,15537,27,10697,0.051388371,1.580938504,0.990319411,2.586377844,0.127627324,DB0067810061224_,2.058640791,0.458018661,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,257598,DB00413,10008479,37,2162,16,1191,0.471487735,1.273847182,0.687945261,2.46351209,0.637699656,DB0041310008479_,0.449887865,0.242041599,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,pramipexole,DB00413
,257622,DB00555,10012218,40,7007,51,3435,8.57553879066571e-06,0.384526277,0.247131834,0.594632859,9.49486255739883e-05,DB0055510012218_,9.262174596,-0.955743152,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,257627,DB00316,10012431,49,65425,20,36933,0.259268407,1.383042679,0.806926456,2.456697187,0.420385545,DB0031610012431_,0.866583024,0.324285912,NA,10012431,Dermatitis,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,257649,DB00563,10013887,58,46588,36,15312,0.003810174,0.529551642,0.343333802,0.826693087,0.016399284,DB0056310013887_,4.110517602,-0.635724588,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,257699,DB00186,10018964,30,16871,28,9980,0.101732113,0.633839223,0.365686324,1.101683052,0.213525588,DB0018610018964_,1.543998604,-0.455959948,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,257712,DB00404,10020993,44,19848,32,9830,0.11215149,0.680978912,0.421889078,1.110301437,0.229301643,DB0040410020993_,1.472716922,-0.38422394,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,alprazolam,DB00404
,257756,DB00413,10030124,36,2163,22,1185,0.680141085,0.896514364,0.51058293,1.607728055,0.806529939,DB0041310030124_,0.215014259,-0.109240964,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,pramipexole,DB00413
,257772,DB00563,10030963,33,46613,22,15326,0.012000278,0.493175508,0.278943162,0.888206494,0.04114627,DB0056310030963_,3.190621991,-0.706890168,NA,10030963,Oral candidiasis,10021881,Infections and infestations,Infec,methotrexate,DB00563
,257819,DB00404,10037368,33,19859,34,9828,0.003858813,0.480334573,0.288176808,0.799805214,0.016563788,DB0040410037368_,4.10053641,-0.73327239,NA,10037368,Pulmonary congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,257883,DB00482,10047942,48,8211,27,3044,0.09012396,0.659088254,0.402223782,1.10068835,0.195406112,DB0048210047942_,1.632675258,-0.416897832,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,celecoxib,DB00482
,258024,DB01156,10002368,50,13572,35,6293,0.062525937,0.662400353,0.421108691,1.052439938,0.148149299,DB0115610002368_,1.909534736,-0.411885143,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,258042,DB00471,10012374,43,14146,7,5458,0.027075612,2.370042079,1.056198783,6.248282858,0.078193974,DB0047110012374_,2.548562694,0.86290771,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,montelukast,DB00471
,258060,DB00588,10013754,49,16475,8,8460,0.001089609,3.145103356,1.476280123,7.692035119,0.005911324,DB0058810013754_,5.130885452,1.145846753,female,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,258105,DB00472,10039203,47,10712,6,4306,0.003596346,3.148941492,1.34211658,9.018511134,0.01565584,DB0047210039203_,4.156911244,1.147066362,female,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,258112,DB00285,10040984,53,10898,19,3699,0.891949424,0.946802658,0.550503403,1.695908097,0.955043713,DB0028510040984_,0.045998166,-0.054664593,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,258126,DB00316,10043431,63,65411,20,36933,0.022278014,1.778573441,1.060834092,3.10668616,0.067245935,DB0031610043431_,2.699398716,0.575811606,NA,10043431,Thinking abnormal,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,258184,DB00564,10002855,42,2562,18,1445,0.416208345,1.315943868,0.738027039,2.438253558,0.585498333,DB0056410002855_,0.535291944,0.274554179,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,carbamazepine,DB00564
,258249,DB00182,10035664,60,5134,27,2825,0.43115881,1.222713837,0.762328352,2.008358102,0.599598398,DB0018210035664_,0.511495184,0.201072844,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,amphetamine,DB00182
,258256,DB00182,10069339,31,5163,22,2830,0.387928238,0.772411071,0.432098987,1.402962974,0.55799363,DB0018210069339_,0.583407732,-0.258238395,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,amphetamine,DB00182
,258288,DB00497,10029350,33,19234,35,16340,0.39470806,0.801000529,0.482210253,1.3277665,0.564620482,DB0049710029350_,0.571601487,-0.221893671,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,258346,DB00741,10008190,22,4072,34,3140,0.014168903,0.499001734,0.277436173,0.880277988,0.047053404,DB0074110008190_,3.056472076,-0.695145708,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,hydrocortisone,DB00741
,258373,DB00741,10039906,43,4051,53,3121,0.022832822,0.625115338,0.406935948,0.95548093,0.068500839,DB0074110039906_,2.680909283,-0.469819105,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,hydrocortisone,DB00741
,258390,DB00203,10019974,57,13821,20,8918,0.018921288,1.838913379,1.087212941,3.234095744,0.059155048,DB0020310019974_,2.827593352,0.609174842,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,sildenafil,DB00203
,258391,DB00374,10019974,62,17654,12,5712,0.105216231,1.671598288,0.891372922,3.410546693,0.218902061,DB0037410019974_,1.519130861,0.513780227,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,treprostinil,DB00374
,258399,DB00203,10064848,47,13831,48,8890,0.026704967,0.629401988,0.411482561,0.962157914,0.07735729,DB0020310064848_,2.559320453,-0.462985136,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,sildenafil,DB00203
,258405,DB13867,10008479,103,4447,33,2521,0.003792698,1.769281365,1.181003244,2.712801514,0.0163428,DB1386710008479_,4.113967846,0.570573456,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,258412,DB13867,10046306,71,4479,25,2529,0.042158489,1.603463942,1.000807834,2.64792271,0.109999592,DB1386710046306_,2.207278623,0.472166253,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,fluticasone,DB13867
,258422,DB00316,10038776,85,65389,33,36920,0.068750062,1.454321419,0.962170967,2.245529942,0.159066369,DB0031610038776_,1.838433751,0.374539413,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,258435,DB00343,10029331,65,8671,49,5046,0.173549449,0.7719918,0.523716743,1.144338027,0.315517172,DB0034310029331_,1.153542171,-0.25878135,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,diltiazem,DB00343
,258459,DB00921,10049177,44,5801,51,4852,0.121108623,0.721634721,0.470045386,1.1039321,0.24301234,DB0092110049177_,1.414643054,-0.326236194,NA,10049177,Drug screen positive,10022891,Investigations,Inv,buprenorphine,DB00921
,258463,DB00188,10000059,49,7837,47,8781,0.473848837,1.168120477,0.765791137,1.783651564,0.639721978,DB0018810000059_,0.446721607,0.155396027,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,258474,DB01195,10012735,56,1183,22,722,0.094730786,1.553197603,0.924039437,2.695475485,0.202857399,DB0119510012735_,1.595252017,0.440315775,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,flecainide,DB01195
,258495,DB00761,10056812,50,15257,23,8602,0.465196155,1.225612315,0.733544444,2.106066145,0.632019483,DB0076110056812_,0.458835058,0.203440568,NA,10056812,Body height decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,258506,DB00316,10001052,109,65365,44,36909,0.063721581,1.39881225,0.976924964,2.033574872,0.150163328,DB0031610001052_,1.896031727,0.335623484,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,258512,DB00959,10001052,27,8051,33,4969,0.010765082,0.504990497,0.291709322,0.867235199,0.03776327,DB0095910001052_,3.276418336,-0.683215667,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,258527,DB00368,10035664,35,625,34,764,0.386506721,1.258146422,0.752418535,2.10584558,0.556645069,DB0036810035664_,0.585827462,0.229639544,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,norepinephrine,DB00368
,258539,DB00678,10076309,101,15498,62,10662,0.522671548,1.120734089,0.808073389,1.564991773,0.681159705,DB0067810076309_,0.383958485,0.113983907,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,258544,DB00207,10016322,65,9015,34,5421,0.53401232,1.149621326,0.746920007,1.798105869,0.690620376,DB0020710016322_,0.37016499,0.139432607,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,258558,DB00787,10017885,69,16931,37,17211,0.001724888,1.895658769,1.252986427,2.909444774,0.008604799,DB0078710017885_,4.755435172,0.639566413,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,258571,DB01068,10060800,63,13700,10,6830,0.000245017,3.14066423,1.598955761,6.869042943,0.001705578,DB0106810060800_,6.373851074,1.144434316,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,clonazepam,DB01068
,258605,DB00186,10046555,36,16865,32,9976,0.102433747,0.665497271,0.401525784,1.107515267,0.214642142,DB0018610046555_,1.538783094,-0.407220743,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,lorazepam,DB00186
,258613,DB01224,10046555,46,8062,20,5897,0.06026031,1.682284972,0.974272565,3.00574372,0.143927595,DB0122410046555_,1.938444918,0.520152972,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,quetiapine,DB01224
,258624,DB00007,10008190,10,1937,50,4402,0.023102312,0.454564074,0.205070555,0.909358013,0.069162219,DB0000710008190_,2.671300533,-0.788416399,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,leuprolide,DB00007
,258625,DB00399,10008190,41,6951,23,4975,0.375924752,1.27583046,0.746692316,2.230223465,0.545725685,DB0039910008190_,0.605638838,0.243597308,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,zoledronic acid,DB00399
,258704,DB00230,10040943,44,19630,24,8627,0.429032476,0.805746433,0.479011605,1.386262315,0.597542384,DB0023010040943_,0.514930063,-0.215986186,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,258717,DB00169,10002544,79,38612,16,18159,0.00127428,2.322048164,1.34470428,4.259621588,0.006714083,DB0016910002544_,5.003547986,0.842449626,NA,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,258778,DB01098,10005750,77,8072,60,7149,0.491989058,1.136578278,0.799184518,1.622977886,0.65501299,DB0109810005750_,0.423100211,0.128022238,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,rosuvastatin,DB01098
,258805,DB00811,10067482,51,2747,57,4099,0.1390062,1.335024377,0.893802113,1.98952479,0.26843316,DB0081110067482_,1.315153334,0.288949551,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,ribavirin,DB00811
,258975,DB06285,10046735,62,8788,14,1092,0.063213114,0.550337749,0.303410293,1.068275809,0.149319857,DB0628510046735_,1.90166458,-0.597223099,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,teriparatide,DB06285
,259063,DB00252,10029864,15,2217,47,1861,2.11010796873866e-06,0.267979979,0.138710054,0.489672665,2.7801597974083e-05,DB0025210029864_,10.49041706,-1.316843006,male,10029864,Nystagmus,10029205,Nervous system disorders,Nerv,phenytoin,DB00252
,259180,DB08931,10059168,53,6524,20,2426,1,0.985424331,0.577894186,1.744015068,1,DB0893110059168_,0,-0.014682938,NA,10059168,Oxygen consumption increased,10022891,Investigations,Inv,riociguat,DB08931
,259213,DB00829,10060800,48,8004,9,4445,0.001266543,2.961637206,1.435574107,6.872398151,0.006680262,DB0082910060800_,5.008598043,1.085742226,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,diazepam,DB00829
,259313,DB00295,10061422,42,14621,12,9590,0.008086988,2.295590441,1.185757419,4.79202292,0.03005244,DB0029510061422_,3.504811433,0.830990083,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,morphine,DB00295
,259370,DB14126,10037844,38,933,32,1244,0.065776319,1.58297351,0.955040542,2.639077037,0.153751049,DB1412610037844_,1.872420551,0.459305047,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,tenofovir,DB14126
,259452,DB00115,10040882,40,18385,25,10447,0.700294873,0.909180917,0.537870849,1.564600247,0.819879108,DB0011510040882_,0.198598379,-0.095211176,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,259476,DB00480,10041052,30,67398,37,67625,0.463751457,0.813544334,0.48533889,1.353548989,0.630953546,DB0048010041052_,0.460523039,-0.206354856,NA,10041052,Sluggishness,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,259477,DB09037,10028411,34,2492,32,2803,0.53543259,1.195056892,0.713172131,2.006912823,0.692014536,DB0903710028411_,0.368148317,0.178193793,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pembrolizumab,DB09037
,259493,DB00563,10069826,43,46603,9,15339,0.260989756,1.57251041,0.755902702,3.669711183,0.422498968,DB0056310069826_,0.861568274,0.45267333,NA,10069826,Inflammatory marker increased,10022891,Investigations,Inv,methotrexate,DB00563
,259517,DB00482,10061428,67,8192,30,3041,0.421863978,0.829092137,0.530294239,1.324005318,0.590908918,DB0048210061428_,0.526093389,-0.187423988,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,celecoxib,DB00482
,259574,DB01220,10011906,227,1067,241,895,0.023307782,0.790155816,0.642219226,0.971862872,0.069610845,DB0122010011906_,2.664834909,-0.235525117,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,rifaximin,DB01220
,259585,DB01220,10019211,35,1259,27,1109,0.699256283,1.141790249,0.666695974,1.974965917,0.81916218,DB0122010019211_,0.199473193,0.132597425,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,rifaximin,DB01220
,259634,DB00425,10033433,42,12653,12,7472,0.023827316,2.066792268,1.067391385,4.315442551,0.070835743,DB0042510033433_,2.647391565,0.725997776,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,259677,DB06218,10013710,28,1666,43,1393,0.015446377,0.544572599,0.323978078,0.902225303,0.05044518,DB0621810013710_,2.986868081,-0.607754014,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,lacosamide,DB06218
,259685,DB00480,10005725,45,67383,54,67608,0.421421925,0.836118126,0.550058291,1.265523973,0.590478173,DB0048010005725_,0.526822607,-0.178985377,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,lenalidomide,DB00480
,259718,DB00051,10039906,79,25652,51,11369,0.0449954,0.686530904,0.476413054,0.997057271,0.115560515,DB0005110039906_,2.157960949,-0.376104038,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,259729,DB00281,10014625,37,11421,33,5638,0.015272656,0.553481361,0.336377853,0.914333841,0.050014549,DB0028110014625_,2.995441343,-0.591527202,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,lidocaine,DB00281
,259777,DB00727,10028372,33,3810,31,4142,0.616004694,1.157254626,0.685591373,1.95794259,0.757244868,DB0072710028372_,0.278068607,0.146050499,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,nitroglycerin,DB00727
,259823,DB00588,10076308,129,16395,31,8437,7.14291588910854e-05,2.141376127,1.436161275,3.283478777,0.000596889,DB0058810076308_,7.42377881,0.761448672,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,259914,DB00364,10011224,81,2669,18,1382,0.000765211,2.329681991,1.378498836,4.144564131,0.004407486,DB0036410011224_,5.424450814,0.845731774,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sucralfate,DB00364
,259972,DB00331,10019851,52,24894,70,20682,0.00824872,0.617182226,0.422407274,0.896785252,0.030524794,DB0033110019851_,3.489216008,-0.482590957,NA,10019851,Hepatotoxicity,10019805,Hepatobiliary disorders,Hepat,metformin,DB00331
,260019,DB08932,10040979,66,19377,23,6574,0.903080567,0.97355202,0.597041362,1.641491954,0.957326661,DB0893210040979_,0.043610607,-0.02680402,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,260212,DB05676,10022000,390,46739,150,25179,0.000402021,1.400652674,1.156602207,1.703471641,0.002573896,DB0567610022000_,5.962334451,0.336938323,NA,10022000,Influenza,10021881,Infections and infestations,Infec,apremilast,DB05676
,260238,DB01267,10039621,28,2824,30,3685,0.506480555,1.217851614,0.699328715,2.114760855,0.667276898,DB0126710039621_,0.404550179,0.197088334,NA,10039621,Schizoaffective disorder,10037175,Psychiatric disorders,Psych,paliperidone,DB01267
,260277,DB00165,10033775,38,2107,14,1352,0.085378704,1.741419986,0.918172503,3.493243059,0.187362742,DB0016510033775_,1.674708743,0.554700865,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,pyridoxine,DB00165
,260376,DB00788,10031161,52,9304,6,5055,2.35401757886158e-05,4.70782026,2.021198032,13.42536178,0.000229551,DB0078810031161_,8.37938727,1.549225011,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,260475,DB01156,10003285,42,13580,16,6312,0.573117443,1.220070167,0.671117037,2.326645439,0.723079655,DB0115610003285_,0.32423589,0.198908371,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,bupropion,DB01156
,260552,DB00451,10062132,47,47224,8,15411,0.086512558,1.917123548,0.897310268,4.699355341,0.189214727,DB0045110062132_,1.664872789,0.650825911,NA,10062132,Tooth extraction,10042613,Surgical and medical procedures,Surg,levothyroxine,DB00451
,260724,DB00333,10010264,66,3005,30,3122,0.000124024,2.285376185,1.45844906,3.656474937,0.000958959,DB0033310010264_,6.949662755,0.826530643,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,methadone,DB00333
,260725,DB00887,10010264,105,2236,51,1764,0.005045167,1.62403821,1.144324713,2.330027587,0.02061116,DB0088710010264_,3.881922584,0.48491577,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,260846,DB00370,10003658,47,4494,21,3642,0.026790398,1.813641596,1.060792654,3.20049505,0.077527867,DB0037010003658_,2.557117834,0.595336755,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,mirtazapine,DB00370
,261028,DB00316,10037876,61,65413,25,36928,0.216238838,1.37746384,0.851759086,2.29054094,0.368900721,DB0031610037876_,0.997227721,0.320244011,NA,10037876,Rash papular,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,261033,DB00047,10040753,63,9222,23,8495,7.98142230364699e-05,2.522924889,1.541477289,4.267079564,0.000657654,DB0004710040753_,7.326831318,0.925418899,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,261096,DB01261,10069339,75,3706,93,3210,0.023172561,0.698560209,0.506419692,0.960963011,0.0692981,DB0126110069339_,2.669337783,-0.358733907,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,sitagliptin,DB01261
,261131,DB00715,10049848,44,4799,19,2268,0.788038354,1.094422469,0.624144237,1.989637013,0.885177161,DB0071510049848_,0.121967473,0.090226799,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,paroxetine,DB00715
,261146,DB01281,10007882,79,8853,15,1783,1,1.060721589,0.604073567,1.988789397,1,DB0128110007882_,0,0.058949421,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,abatacept,DB01281
,261157,DB00788,10042682,46,9310,15,5046,0.105869212,1.662072569,0.910187322,3.208428721,0.2199733,DB0078810042682_,1.514249102,0.508065359,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,naproxen,DB00788
,261214,DB00181,10010144,349,9507,176,5695,0.066599097,1.187800674,0.985076233,1.436358805,0.155218769,DB0018110010144_,1.862919747,0.172103424,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,baclofen,DB00181
,261215,DB00186,10010144,797,16104,512,9496,0.142741289,0.917904118,0.818003525,1.03069027,0.273645801,DB0018610010144_,1.295920707,-0.085662341,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,261216,DB00231,10010144,246,3050,206,1933,0.005636227,0.756886366,0.620822376,0.923451109,0.022523485,DB0023110010144_,3.793196719,-0.278542148,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,temazepam,DB00231
,261299,DB01238,10061284,58,5192,26,3476,0.093903979,1.493414793,0.923174347,2.476797528,0.20159808,DB0123810061284_,1.601479267,0.401065305,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,261320,DB08880,10047571,46,3292,11,798,1,1.013695313,0.514316772,2.180377974,1,DB0888010047571_,0,0.01360238,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,teriflunomide,DB08880
,261326,DB00177,10030095,39,4761,16,2834,0.262611305,1.450862262,0.790574044,2.786383652,0.42440841,DB0017710030095_,0.857059056,0.372158043,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,valsartan,DB00177
,261407,DB00073,10039906,58,7348,28,6379,0.012175055,1.798184929,1.125190577,2.936320031,0.041631594,DB0007310039906_,3.178895918,0.586777783,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,rituximab,DB00073
,261416,DB01202,10022086,31,6683,21,5697,0.486344851,1.258371138,0.699436152,2.306762559,0.650216139,DB0120210022086_,0.43045045,0.229818137,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,261457,DB08868,10002948,54,9148,10,2501,0.288292482,1.476262907,0.742926301,3.256378992,0.453304061,DB0886810002948_,0.791192161,0.389513831,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,261488,DB06637,10010305,61,6101,16,2003,0.507005747,1.251628836,0.710632139,2.331447272,0.667650914,DB0663710010305_,0.403989826,0.224445772,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,dalfampridine,DB06637
,261489,DB08868,10010305,124,9078,28,2483,0.425917479,1.211274106,0.796398766,1.901183296,0.594684919,DB0886810010305_,0.519723562,0.191672786,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,fingolimod,DB08868
,261553,DB06637,10025482,130,6032,29,1990,0.062837497,1.478789218,0.97911484,2.30241265,0.148686466,DB0663710025482_,1.905915443,0.391223657,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,261621,DB01050,10044390,34,18074,25,9346,0.215355904,0.703234259,0.407115587,1.230378808,0.367839765,DB0105010044390_,1.000107856,-0.352065214,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,ibuprofen,DB01050
,261664,DB00207,10047571,50,9030,9,5446,0.000227411,3.350326104,1.629431684,7.755928427,0.001605126,DB0020710047571_,6.434553329,1.209057686,female,10047571,Visual impairment,10015919,Eye disorders,Eye,azithromycin,DB00207
,261666,DB00321,10047571,42,7405,13,2837,0.549429627,1.237733452,0.650605466,2.516895083,0.703755068,DB0032110047571_,0.351324898,0.213281846,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,amitriptyline,DB00321
,261731,DB00316,10061920,63,65411,24,36929,0.117453576,1.481987016,0.912718107,2.480660528,0.237326921,DB0031610061920_,1.438316673,0.393383766,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,261809,DB00497,10048393,62,19205,23,16352,0.000435111,2.295083937,1.401173853,3.883502211,0.002749582,DB0049710048393_,5.896306431,0.830769417,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,261840,DB00783,10069339,65,16649,6,367,0.00451509,0.238844341,0.10307461,0.678944455,0.018820036,DB0078310069339_,3.972833213,-1.431943232,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,estradiol,DB00783
,261885,DB06273,10020751,93,5002,14,1396,0.032435833,1.853741088,1.047174356,3.533276223,0.090048148,DB0627310020751_,2.407410774,0.617205807,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,tocilizumab,DB06273
,261903,DB00331,10035742,31,24915,31,20721,0.52389265,0.831673495,0.488790719,1.415179269,0.681962031,DB0033110035742_,0.382781296,-0.184315349,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,262015,DB06403,10042682,160,21311,38,6623,0.153572811,1.308518419,0.91271371,1.918428322,0.288921114,DB0640310042682_,1.241601592,0.26889552,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,262149,DB00295,10076309,82,14581,60,9542,0.547072363,0.89437082,0.632606347,1.270724689,0.701728792,DB0029510076309_,0.354208286,-0.111634803,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,262243,DB00341,10065154,51,11354,14,5054,0.137552482,1.621500093,0.883046798,3.175229556,0.266287989,DB0034110065154_,1.323176891,0.483351704,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,cetirizine,DB00341
,262249,DB01222,10065154,39,9235,36,5369,0.054133621,0.62987248,0.389503073,1.02101111,0.132709665,DB0122210065154_,2.019591508,-0.462237893,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,budesonide,DB01222
,262276,DB00065,10013745,91,9373,50,4907,0.789641176,0.952819143,0.666305931,1.376258477,0.886030962,DB0006510013745_,0.121003383,-0.048330169,NA,10013745,Drug specific antibody present,10022891,Investigations,Inv,infliximab,DB00065
,262286,DB00904,10042682,89,22980,47,14409,0.377714557,1.187296663,0.824224124,1.729776336,0.54770382,DB0090410042682_,0.602020613,0.171679011,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,262300,DB00515,10061188,29,1841,30,2121,0.695241567,1.113657518,0.642331255,1.928162937,0.816560818,DB0051510061188_,0.202653883,0.10764966,NA,10061188,Haematotoxicity,10005329,Blood and lymphatic system disorders,Blood,cisplatin,DB00515
,262321,DB00959,10021789,87,7991,39,4963,0.097498723,1.385438766,0.937559168,2.080184923,0.207107964,DB0095910021789_,1.574515058,0.326016888,NA,10021789,Infection,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,262396,DB00059,10001551,25,802,40,1067,0.524944746,0.831593535,0.479239497,1.418048246,0.683060946,DB0005910001551_,0.38117119,-0.184411497,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,pegaspargase,DB00059
,262428,DB01098,10023547,31,8118,37,7172,0.225314284,0.740222621,0.443573107,1.227545375,0.38016407,DB0109810023547_,0.967152357,-0.300804299,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,rosuvastatin,DB01098
,262443,DB00798,10013700,89,718,20,624,5.02972324434831e-09,3.863981931,2.326595143,6.709718202,1.20681219057686e-07,DB0079810013700_,15.93011332,1.35169824,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,gentamicin,DB00798
,262452,DB06637,10065154,228,5934,61,1958,0.164767296,1.233264396,0.921320064,1.671879514,0.303816793,DB0663710065154_,1.191330415,0.209664634,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,dalfampridine,DB06637
,262468,DB00950,10008531,60,4658,17,2039,0.134196803,1.544880795,0.886902452,2.831536405,0.261586486,DB0095010008531_,1.34099032,0.434946752,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,262496,DB00710,10047700,79,2327,8,193,0.540607166,0.819095162,0.388294587,1.992284,0.696118129,DB0071010047700_,0.362235908,-0.199555009,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ibandronate,DB00710
,262499,DB01098,10022004,45,8104,34,7175,0.500115507,1.171794226,0.733141554,1.888651998,0.661728287,DB0109810022004_,0.41290025,0.1585361,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,262504,DB00715,10013950,44,4799,15,2272,0.327274681,1.388699332,0.756155983,2.692482634,0.495702143,DB0071510013950_,0.70178005,0.328367577,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,paroxetine,DB00715
,262529,DB00904,10019301,42,23027,23,14433,0.70226519,1.144591685,0.672439746,1.994666039,0.821369191,DB0090410019301_,0.196782586,0.135047966,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,ondansetron,DB00904
,262546,DB01611,10069339,99,11814,36,2325,0.003302139,0.541236829,0.365103143,0.81842002,0.014619627,DB0161110069339_,4.225390324,-0.613898334,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,hydroxychloroquine,DB01611
,262557,DB06637,10003591,34,6128,16,2003,0.248924836,0.69461208,0.372154623,1.350695275,0.408362572,DB0663710003591_,0.895599842,-0.364401747,NA,10003591,Ataxia,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,262617,DB00472,10018100,30,10729,33,4279,7.03808959411484e-05,0.362596629,0.21331978,0.614109227,0.000589254,DB0047210018100_,7.436653813,-1.014464276,male,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,262661,DB00641,10013082,34,14090,18,12457,0.094339693,1.669933862,0.916488903,3.142500953,0.202284631,DB0064110013082_,1.598079509,0.512784022,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,262668,DB00373,10015958,52,1780,14,1273,0.000873856,2.655581677,1.442506892,5.211734161,0.00493062,DB0037310015958_,5.312290536,0.976663718,NA,10015958,Eye pain,10015919,Eye disorders,Eye,timolol,DB00373
,262689,DB00465,10010774,58,2046,18,865,0.308356168,1.36219997,0.78563806,2.471739665,0.475638905,DB0046510010774_,0.743096316,0.309101018,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ketorolac,DB00465
,262800,DB01104,10013654,214,15249,201,7085,3.0565120999583e-12,0.494672645,0.405278339,0.604020487,1.26520347318746e-10,DB0110410013654_,22.79061797,-0.703859058,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,262820,DB06674,10051792,45,4461,12,1478,0.643922928,1.242383785,0.644202172,2.587533611,0.780197279,DB0667410051792_,0.24820847,0.217031942,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,golimumab,DB06674
,262918,DB00904,10044066,72,22997,53,14403,0.407476738,0.850830171,0.588104567,1.237835016,0.576920338,DB0090410044066_,0.550051085,-0.161542734,NA,10044066,Torsade de pointes,10007541,Cardiac disorders,Card,ondansetron,DB00904
,262971,DB00471,10016334,53,14136,11,5454,0.068270811,1.858945275,0.958733647,3.950026085,0.158168284,DB0047110016334_,1.844095726,0.62000927,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,262993,DB00465,10037087,44,2060,13,870,0.305980979,1.429309028,0.751458619,2.907563623,0.472878059,DB0046510037087_,0.748917728,0.357191131,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ketorolac,DB00465
,263000,DB00471,10037855,31,14158,19,5446,0.114720936,0.62761772,0.343184579,1.176938578,0.233212669,DB0047110037855_,1.4558045,-0.465824024,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,263067,DB01175,10011469,45,10679,9,4883,0.018568627,2.286161768,1.102453354,5.322946229,0.058277774,DB0117510011469_,2.842534492,0.826874328,NA,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,263298,DB01592,10043607,57,6219,44,3023,0.024927368,0.629729542,0.416412499,0.957882476,0.07331907,DB0159210043607_,2.612934543,-0.46246485,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,iron,DB01592
,263306,DB00193,10057668,51,19269,20,8682,0.700310035,1.148936691,0.672566857,2.035916489,0.819879108,DB0019310057668_,0.198598379,0.138836898,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,263338,DB00678,10007617,25,15574,32,10692,0.021333529,0.536377907,0.304553334,0.934698326,0.065086393,DB0067810007617_,2.732039766,-0.622916317,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,losartan,DB00678
,263344,DB00213,10014387,55,18840,51,13370,0.168616825,0.76533502,0.512874704,1.143799449,0.309050502,DB0021310014387_,1.174250579,-0.267441607,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,pantoprazole,DB00213
,263349,DB00472,10014387,75,10684,52,4260,0.002942681,0.575123031,0.397662605,0.837182249,0.013294476,DB0047210014387_,4.320406684,-0.553171294,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,fluoxetine,DB00472
,263357,DB01118,10014387,36,3027,81,4628,0.056715203,0.679546591,0.444375167,1.021169525,0.137314487,DB0111810014387_,1.98548146,-0.386329481,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,amiodarone,DB01118
,263392,DB00829,10005750,72,7980,23,4431,0.023355928,1.738144228,1.072202162,2.917543038,0.069699202,DB0082910005750_,2.663566417,0.552818008,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,diazepam,DB00829
,263432,DB00182,10062355,57,5137,34,2818,0.741155933,0.919671346,0.589536314,1.454399082,0.851510532,DB0018210062355_,0.16074341,-0.083738905,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,263683,DB00619,10033371,67,2832,46,2448,0.25306661,1.258972507,0.848645212,1.881939119,0.413459805,DB0061910033371_,0.883194976,0.230295917,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,263704,DB00537,10039906,57,7500,32,4266,1,1.013174155,0.644868152,1.617340839,1,DB0053710039906_,0,0.01308813,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,263707,DB00683,10039906,40,1544,42,1596,1,0.984458999,0.618460864,1.564973913,1,DB0068310039906_,0,-0.015663028,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,midazolam,DB00683
,263712,DB11089,10039906,82,10093,76,8331,0.471314416,0.890595063,0.642933276,1.234998998,0.637530847,DB1108910039906_,0.450152616,-0.11586543,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,docusate,DB11089
,263777,DB00537,10049848,34,7523,19,4279,1,1.017832001,0.56354793,1.891368089,1,DB0053710049848_,0,0.017674876,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,263835,DB00213,10057668,46,18849,24,13397,0.227434254,1.362264622,0.814037105,2.33464448,0.382647978,DB0021310057668_,0.960639831,0.309148478,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,263851,DB11089,10057668,28,10147,32,8375,0.242342551,0.722215382,0.418594871,1.239376919,0.400564311,DB1108910057668_,0.914880948,-0.325431872,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,docusate,DB11089
,263942,DB00497,10007739,49,19218,29,16346,0.139092612,1.437130128,0.889552665,2.360510979,0.268540843,DB0049710007739_,1.314752262,0.362648159,NA,10007739,Cataract,10015919,Eye disorders,Eye,oxycodone,DB00497
,263949,DB09053,10020772,38,2247,52,4000,0.225252642,1.300793197,0.830132314,2.021877104,0.380133266,DB0905310020772_,0.967233388,0.26297423,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ibrutinib,DB09053
,263979,DB00874,10010264,41,3294,35,1941,0.120209643,0.690342356,0.427331372,1.120626132,0.241656612,DB0087410010264_,1.420237521,-0.370567637,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,264034,DB04861,10003988,38,1927,29,1358,0.802461122,0.923452009,0.551588266,1.560738148,0.893152549,DB0486110003988_,0.112997885,-0.079636447,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,nebivolol,DB04861
,264040,DB00695,10023644,52,27997,26,20502,0.135399367,1.464572737,0.897687888,2.444394731,0.26326681,DB0069510023644_,1.334587276,0.381563553,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,furosemide,DB00695
,264048,DB06403,10039101,126,21345,29,6632,0.15574249,1.349932576,0.894835277,2.099335838,0.291781279,DB0640310039101_,1.231750802,0.300054647,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,264091,DB00451,10024570,85,47186,18,15401,0.108315782,1.541232173,0.918734525,2.725213052,0.223530451,DB0045110024570_,1.498207626,0.432582209,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,levothyroxine,DB00451
,264132,DB00333,10020642,21,3050,49,3103,0.001095946,0.436046223,0.247771621,0.742936498,0.005937737,DB0033310020642_,5.126427174,-0.830007025,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,methadone,DB00333
,264158,DB00193,10050819,37,19283,21,8681,0.396342542,0.793225329,0.452013391,1.427135685,0.565971004,DB0019310050819_,0.569212431,-0.231647951,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,264188,DB06589,10001760,37,1993,21,2632,0.001963027,2.32640606,1.321879709,4.197082162,0.009587174,DB0658910001760_,4.647329077,0.844324613,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,pazopanib,DB06589
,264296,DB09270,10008469,33,3081,19,2349,0.3990616,1.32412665,0.729041117,2.471319433,0.568928468,DB0927010008469_,0.564000569,0.28075311,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,264297,DB14513,10008469,46,7131,9,3555,0.006306423,2.547843424,1.230420088,5.927585552,0.024645307,DB1451310008469_,3.703168784,0.935247285,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,264337,DB05676,10012601,58,47071,32,25297,0.912188887,0.974059568,0.621932442,1.550575283,0.960594091,DB0567610012601_,0.040203341,-0.026282819,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,apremilast,DB05676
,264340,DB05676,10022998,91,47038,76,25253,0.005569906,0.642803147,0.468621383,0.883872024,0.022304231,DB0567610022998_,3.802978894,-0.44191675,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,264352,DB00213,10016825,122,18773,43,13378,4.67085228003806e-05,2.021796581,1.416327447,2.93513524,0.000416887,DB0021310016825_,7.782694292,0.703986512,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,pantoprazole,DB00213
,264551,DB00028,10020937,77,13381,29,5586,0.670751069,1.108413758,0.71372449,1.764669444,0.800249273,DB0002810020937_,0.222832009,0.102929946,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,264586,DB00199,10019211,61,2649,15,685,1,1.05160154,0.586075877,2.004907118,1,DB0019910019211_,0,0.050314278,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,erythromycin,DB00199
,264627,DB00836,10040753,74,5461,25,4050,0.000460024,2.195015374,1.375415425,3.613099027,0.0028807,DB0083610040753_,5.849721982,0.786189051,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,loperamide,DB00836
,264636,DB00196,10046306,40,5043,11,3274,0.009261648,2.360565491,1.186593382,5.109391018,0.033478981,DB0019610046306_,3.396837475,0.858901205,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,fluconazole,DB00196
,264665,DB01060,10014011,66,8521,36,5045,0.758045283,1.085459668,0.711425023,1.680185488,0.864834475,DB0106010014011_,0.145217149,0.082003554,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,264726,DB00177,10037087,115,4685,37,2813,0.000888806,1.866050596,1.274031298,2.789626031,0.005001558,DB0017710037087_,5.298005842,0.623824217,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,valsartan,DB00177
,264755,DB01104,10062244,45,15418,12,7274,0.087625129,1.769158628,0.919765734,3.676521343,0.191210536,DB0110410062244_,1.654380175,0.570504082,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,264789,DB08910,10001949,43,16701,58,17430,0.231597657,0.773748101,0.508794896,1.168617164,0.38785285,DB0891010001949_,0.947129263,-0.256508909,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,264800,DB08815,10002855,55,1399,15,688,0.051039545,1.802752085,0.995431206,3.461316518,0.126979739,DB0881510002855_,2.063727744,0.589314434,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,lurasidone,DB08815
,264804,DB08910,10005750,104,16640,69,17419,0.00365118,1.577775881,1.15181451,2.172868326,0.015852539,DB0891010005750_,4.144425628,0.456016185,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,pomalidomide,DB08910
,264812,DB08815,10016256,53,1401,27,676,0.808970039,0.947178853,0.579288784,1.581095561,0.896971703,DB0881510016256_,0.108730963,-0.054267341,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lurasidone,DB08815
,264820,DB08910,10028372,85,16659,74,17414,0.266024357,1.200697949,0.868159444,1.663806475,0.428144148,DB0891010028372_,0.848295347,0.182903012,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,pomalidomide,DB08910
,264837,DB01076,10024774,50,25697,66,25517,0.13728063,0.752275855,0.510017222,1.103477202,0.265941067,DB0107610024774_,1.324480546,-0.284652194,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,264838,DB01136,10024774,21,9863,36,11079,0.143672643,0.655266948,0.363199355,1.154043717,0.275059938,DB0113610024774_,1.290766249,-0.422712572,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,carvedilol,DB01136
,264849,DB01104,10043417,36,15427,22,7264,0.327510163,0.770542209,0.440809035,1.376014027,0.495930214,DB0110410043417_,0.701320059,-0.260660844,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,264859,DB01068,10005191,44,13719,11,6829,0.043772561,1.991048529,1.011052177,4.277621614,0.113132916,DB0106810005191_,2.179191904,0.688661399,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,clonazepam,DB01068
,264891,DB00869,10015958,38,1267,24,905,0.696186917,1.130854497,0.655796727,1.985683532,0.817223701,DB0086910015958_,0.201842414,0.122973539,NA,10015958,Eye pain,10015919,Eye disorders,Eye,dorzolamide,DB00869
,264903,DB01029,10037844,51,1289,15,886,0.003161449,2.336199231,1.283297179,4.502889687,0.014124024,DB0102910037844_,4.259878089,0.848525349,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,irbesartan,DB01029
,265065,DB00007,10047899,46,1901,38,4414,3.51832978419059e-06,2.810252893,1.78233798,4.453927799,4.34277052723408e-05,DB0000710047899_,10.04441295,1.033274477,female,10047899,Weight increased,10022891,Investigations,Inv,leuprolide,DB00007
,265095,DB00863,10035226,40,10633,32,5808,0.109591987,0.682767154,0.417738496,1.124262828,0.225462793,DB0086310035226_,1.48960013,-0.381601393,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ranitidine,DB00863
,265173,DB00470,10035664,42,877,58,895,0.151225432,0.739121986,0.479164662,1.131876844,0.285557506,DB0047010035664_,1.253311848,-0.302292303,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,dronabinol,DB00470
,265234,DB05676,10013952,42,47087,14,25315,0.125103909,1.612855254,0.863251498,3.19824223,0.248788064,DB0567610013952_,1.391153893,0.478006058,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,265314,DB00199,10020751,50,2660,6,694,0.067667635,2.173730557,0.926300066,6.230090773,0.157151775,DB0019910020751_,1.850543218,0.776444842,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,erythromycin,DB00199
,265327,DB01281,10060795,46,8886,10,1788,0.85723296,0.9255819,0.459646099,2.061060156,0.931519401,DB0128110060795_,0.070938262,-0.077332658,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,abatacept,DB01281
,265353,DB00177,10006451,63,4737,17,2833,0.002408631,2.216125396,1.277734556,4.048697096,0.011322697,DB0017710006451_,4.480945963,0.795760354,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,valsartan,DB00177
,265359,DB00804,10006451,44,2956,10,889,0.516263209,1.323175118,0.652724719,2.961347531,0.675921593,DB0080410006451_,0.391678196,0.28003424,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,dicyclomine,DB00804
,265370,DB00804,10011224,65,2935,12,887,0.132825519,1.636765249,0.871346654,3.345173918,0.25972243,DB0080410011224_,1.348141797,0.492721885,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dicyclomine,DB00804
,265444,DB00761,10049414,50,15257,31,8594,0.728216586,0.908525747,0.568620322,1.472542692,0.841462709,DB0076110049414_,0.172613581,-0.095932051,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,265450,DB00203,10053459,30,13848,20,8918,0.885938101,0.965967026,0.530359201,1.79580923,0.952535694,DB0020310053459_,0.048627699,-0.03462558,NA,10053459,Secretion discharge,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,265504,DB00727,10001053,24,3819,32,4141,0.502976088,0.813258322,0.457445508,1.427685544,0.664124502,DB0072710001053_,0.409285644,-0.206706481,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nitroglycerin,DB00727
,265506,DB06605,10001053,72,14001,53,12980,0.210149972,1.259412177,0.870324517,1.832634541,0.361360201,DB0660510001053_,1.01788003,0.230645086,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,265511,DB00243,10002034,17,1237,34,1592,0.155162387,0.643588122,0.33551267,1.190886068,0.291006961,DB0024310002034_,1.234408093,-0.44069632,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ranolazine,DB00243
,265541,DB06605,10008479,267,13806,154,12879,1.7215465272324e-06,1.617317401,1.319414273,1.988141782,2.32055643427199e-05,DB0660510008479_,10.67111847,0.480768851,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,265580,DB06605,10017885,77,13996,24,13009,6.37573500369228e-07,2.981727064,1.863478674,4.934999776,9.60104237021207e-06,DB0660510017885_,11.55363889,1.092502684,female,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,265615,DB00813,10065154,35,10537,28,10140,0.528560392,1.20289193,0.710356066,2.054364054,0.68593201,DB0081310065154_,0.376976767,0.184728599,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,fentanyl,DB00813
,265624,DB01050,10070608,40,18068,22,9349,0.790423407,0.940792227,0.545516783,1.663080362,0.886473405,DB0105010070608_,0.120504154,-0.061032964,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,265626,DB14512,10070608,85,4759,50,2362,0.356899719,0.843780187,0.585912254,1.22619595,0.526584851,DB1451210070608_,0.6413428,-0.16986326,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,mometasone furoate,DB14512
,265652,DB00540,10022437,59,2424,26,1065,1,0.99700197,0.614714163,1.657651171,1,DB0054010022437_,0,-0.003002533,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,nortriptyline,DB00540
,265697,DB01039,10030124,34,2939,32,3019,0.804724928,1.091389636,0.651570906,1.83222778,0.894427482,DB0103910030124_,0.11157145,0.08745178,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,265748,DB00186,10020919,47,16854,22,9986,0.385448243,1.265803754,0.74730058,2.206914738,0.555592502,DB0018610020919_,0.587720163,0.235707299,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,lorazepam,DB00186
,265757,DB06228,10020919,96,15816,49,16027,8.0099375361353e-05,1.985267678,1.392034869,2.863080718,0.000659797,DB0622810020919_,7.323578415,0.685753755,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,rivaroxaban,DB06228
,265761,DB00472,10019063,57,10702,47,4265,0.000298848,0.483327513,0.322162316,0.728231721,0.002011064,DB0047210019063_,6.209091571,-0.727060775,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,265767,DB01076,10019063,111,25636,171,25412,0.000323963,0.643460259,0.501779033,0.822418792,0.002148986,DB0107610019063_,6.142758984,-0.440895011,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,265970,DB01276,10057880,141,1876,134,1377,0.042275106,0.772417501,0.599053646,0.996325631,0.110243678,DB0127610057880_,2.205062105,-0.25823007,NA,10057880,Injection site nodule,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,265987,DB06186,10062767,74,2135,119,3527,0.88005477,1.027299991,0.754031105,1.392014303,0.949657804,DB0618610062767_,0.051653566,0.026933993,NA,10062767,Hypophysitis,10014698,Endocrine disorders,Endo,ipilimumab,DB06186
,265999,DB01050,10027091,31,18077,35,9336,0.001661282,0.457439986,0.272594183,0.764306441,0.008351688,DB0105010027091_,4.78529159,-0.782109582,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,266044,DB08895,10000496,150,27964,47,6599,0.101340104,0.753141095,0.53879113,1.069876149,0.212876579,DB0889510000496_,1.547042722,-0.283502691,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,266052,DB01611,10022004,59,11854,13,2348,0.749932294,0.89894487,0.486469448,1.789790843,0.85838575,DB0161110022004_,0.152701689,-0.10653357,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,266056,DB00404,10027091,45,19847,24,9838,0.798295728,0.929426323,0.553966526,1.595927694,0.891009846,DB0040410027091_,0.115399801,-0.07318774,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,266100,DB00273,10037660,91,8390,31,2162,0.177505076,0.756459841,0.496739731,1.180169651,0.320657085,DB0027310037660_,1.137382997,-0.279105832,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,266132,DB00737,10039906,38,2763,18,914,0.214800112,0.698428278,0.386705462,1.306898955,0.367173112,DB0073710039906_,1.001921847,-0.358922786,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,meclizine,DB00737
,266254,DB00999,10022998,70,21360,43,12196,0.696421415,0.929495194,0.626453234,1.393224026,0.817353208,DB0099910022998_,0.201683954,-0.073113643,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,266304,DB00776,10003239,38,1867,16,1323,0.094072778,1.682721934,0.911650711,3.246877572,0.201861543,DB0077610003239_,1.600173249,0.520412681,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,oxcarbazepine,DB00776
,266328,DB08895,10005557,105,28009,34,6612,0.129229795,0.729038244,0.490476567,1.108375089,0.25450906,DB0889510005557_,1.368418844,-0.316029087,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,tofacitinib,DB08895
,266509,DB01195,10021097,68,1171,50,694,0.281145308,0.806112412,0.544223056,1.20070296,0.445107931,DB0119510021097_,0.809438484,-0.215532077,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,flecainide,DB01195
,266525,DB06605,10034476,27,14046,48,12985,0.00737506,0.520026755,0.311803576,0.850858284,0.027912663,DB0660510034476_,3.578674821,-0.653875017,NA,10034476,Pericardial haemorrhage,10007541,Cardiac disorders,Card,apixaban,DB06605
,266532,DB01611,10038435,50,11863,16,2345,0.096897918,0.617756094,0.34526719,1.164293659,0.206110667,DB0161110038435_,1.579342038,-0.48166157,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,hydroxychloroquine,DB01611
,266540,DB01137,10048294,50,7722,36,5557,1,0.999489228,0.637324555,1.581578261,1,DB0113710048294_,0,-0.000510903,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,levofloxacin,DB01137
,266564,DB00370,10038669,45,4496,27,3636,0.235506693,1.347814898,0.816559375,2.263734452,0.392648087,DB0037010038669_,0.93484152,0.298484687,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mirtazapine,DB00370
,266565,DB00656,10038669,117,11896,68,6551,0.757565502,0.947512767,0.695671379,1.299172306,0.864468915,DB0065610038669_,0.145639932,-0.053914867,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,266569,DB01050,10038669,64,18044,44,9327,0.154687275,0.751893887,0.503858112,1.13105007,0.290378579,DB0105010038669_,1.236569763,-0.285160073,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,266599,DB08895,10054236,44,28070,6,6640,0.278352571,1.734670291,0.736072098,4.983459773,0.442164582,DB0889510054236_,0.816073109,0.550817361,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,266712,DB01104,10052904,102,15361,38,7248,0.237794244,1.266479873,0.86374787,1.891933477,0.395271087,DB0110410052904_,0.928183454,0.236241298,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,266784,DB00656,10020993,32,11981,56,6563,1.24222504417348e-07,0.313040051,0.195955945,0.492374628,2.21518896106513e-06,DB0065610020993_,13.02017285,-1.16142414,male,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,trazodone,DB00656
,266785,DB00046,10024855,47,5412,27,4665,0.101591734,1.500409674,0.913847616,2.509511441,0.213285841,DB0004610024855_,1.545122038,0.405738187,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,insulin lispro,DB00046
,266794,DB00641,10039203,32,14092,29,12446,1,0.97455577,0.570647472,1.670775639,1,DB0064110039203_,0,-0.025773533,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,266810,DB00999,10012671,35,21395,33,12206,0.043040325,0.605123124,0.365025724,1.005170749,0.111762404,DB0099910012671_,2.191380049,-0.502323331,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,266816,DB00555,10010144,884,6163,461,3025,0.33621278,0.941211933,0.832982842,1.064432828,0.505294772,DB0055510010144_,0.682613314,-0.060586944,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,266820,DB06674,10013968,74,4432,12,1478,0.016745348,2.056384405,1.105780722,4.170628817,0.053726147,DB0667410013968_,2.923855478,0.720949297,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,golimumab,DB06674
,266868,DB00706,10022086,6,1069,45,15880,0.136740025,1.980575776,0.688925674,4.670545112,0.26515137,DB0070610022086_,1.32745441,0.683387598,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,tamsulosin,DB00706
,266986,DB00051,10048592,51,25680,20,11400,0.700630616,1.132000976,0.662770365,2.005458062,0.820041222,DB0005110048592_,0.198400669,0.123986842,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,266991,DB00051,10056819,59,25672,17,11403,0.134897161,1.541556556,0.885989059,2.822254692,0.26248524,DB0005110056819_,1.337560428,0.432792657,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,adalimumab,DB00051
,267093,DB01065,10011224,98,4233,38,3013,0.001466247,1.835515381,1.246093965,2.752982549,0.00754878,DB0106510011224_,4.886369324,0.607325304,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,melatonin,DB01065
,267100,DB01065,10040753,66,4265,30,3021,0.047322092,1.558220211,0.994823178,2.492459576,0.120058026,DB0106510040753_,2.119780099,0.443544279,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,melatonin,DB01065
,267110,DB01076,10009657,41,25706,31,25552,0.288622957,1.314646416,0.804287115,2.168924195,0.453667479,DB0107610009657_,0.790390773,0.273567744,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,267206,DB00688,10044565,75,6415,72,5306,0.404612472,0.861599922,0.613825374,1.210159256,0.574381012,DB0068810044565_,0.554462319,-0.148964244,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,mycophenolate mofetil,DB00688
,267211,DB01306,10044565,36,4172,34,3832,0.90514229,0.972530484,0.590180257,1.605645437,0.95771939,DB0130610044565_,0.043200456,-0.027853858,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,insulin aspart,DB01306
,267381,DB06643,10064848,43,52378,11,7504,0.096666959,0.560048447,0.283853715,1.204804485,0.205765155,DB0664310064848_,1.581019785,-0.579731986,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,denosumab,DB06643
,267412,DB08895,10007882,132,27982,41,6605,0.145182986,0.759955389,0.531049724,1.108148778,0.277313037,DB0889510007882_,1.282608312,-0.274495546,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,267420,DB00887,10000060,56,2285,28,1787,0.058815581,1.563948953,0.97215432,2.568501098,0.141242295,DB0088710000060_,1.957278461,0.447214003,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,bumetanide,DB00887
,267438,DB00887,10013971,61,2280,41,1774,0.544436798,1.157565786,0.762537898,1.77310068,0.699438965,DB0088710013971_,0.357476743,0.14631934,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bumetanide,DB00887
,267440,DB01088,10013971,57,1372,6,431,0.006086295,2.983197612,1.276893218,8.526249975,0.023939882,DB0108810013971_,3.732209501,1.09299575,female,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iloprost,DB01088
,267448,DB00887,10028334,35,2306,22,1793,0.502118723,1.236927368,0.702734773,2.221884049,0.663444193,DB0088710028334_,0.410310539,0.212630376,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,bumetanide,DB00887
,267454,DB00586,10028735,39,7070,16,2789,0.881333926,0.961556104,0.524085839,1.846244569,0.950394349,DB0058610028735_,0.050878277,-0.039202365,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diclofenac,DB00586
,267480,DB00586,10039101,38,7071,16,2789,0.879640222,0.936768295,0.509058596,1.802628986,0.949457398,DB0058610039101_,0.051864617,-0.065319312,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diclofenac,DB00586
,267503,DB00051,10027175,122,25609,44,11376,0.272962679,1.231670293,0.865303049,1.781897311,0.435947032,DB0005110027175_,0.830234528,0.20837121,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,adalimumab,DB00051
,267519,DB00635,10003662,30,33023,28,23766,0.352133529,0.77109738,0.445048717,1.339834963,0.521881526,DB0063510003662_,0.650314679,-0.25994061,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,prednisone,DB00635
,267564,DB01065,10047899,98,4233,39,3012,0.002076741,1.787863729,1.217884831,2.670112332,0.010032611,DB0106510047899_,4.601914412,0.58102146,NA,10047899,Weight increased,10022891,Investigations,Inv,melatonin,DB01065
,267599,DB06605,10020100,70,14003,46,12987,0.076669483,1.411305867,0.958379469,2.095916206,0.172657415,DB0660510020100_,1.756445908,0.344515423,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,267651,DB06724,10033775,91,7838,26,3893,0.013193282,1.738316615,1.11151953,2.806314144,0.044402741,DB0672410033775_,3.114454075,0.552917182,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,calcium carbonate,DB06724
,267748,DB08932,10017853,43,19400,8,6589,0.145609006,1.825424896,0.847835959,4.498400962,0.27789673,DB0893210017853_,1.28050571,0.60181278,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,267783,DB00279,10012735,76,1161,8,208,0.20469583,1.701439881,0.804985415,4.144495939,0.35468736,DB0027910012735_,1.036518554,0.531474881,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,liothyronine,DB00279
,267791,DB08893,10028813,99,1986,27,1031,0.002743286,1.903142666,1.223607869,3.051439375,0.012568224,DB0889310028813_,4.376583595,0.643506555,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,mirabegron,DB08893
,267825,DB01136,10022523,51,9833,17,11098,3.91902113912254e-06,3.385762719,1.921535766,6.256801186,4.77125848271589e-05,DB0113610022523_,9.950315362,1.219579204,female,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,267831,DB00722,10038743,45,25358,26,26006,0.023368522,1.774965736,1.071436312,2.998061254,0.06972491,DB0072210038743_,2.66319763,0.573781119,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,267966,DB01181,10029354,51,522,83,837,1,0.985260514,0.669245425,1.439330236,1,DB0118110029354_,0,-0.014849191,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,ifosfamide,DB01181
,268050,DB00341,10058080,48,11357,20,5048,0.895564056,1.066755736,0.620475202,1.89953949,0.95615204,DB0034110058080_,0.044838341,0.06462202,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,cetirizine,DB00341
,268077,DB00921,10030124,59,5786,27,4876,0.008778294,1.841403095,1.147249347,3.025569268,0.032075828,DB0092110030124_,3.439652569,0.610527833,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,268129,DB00115,10019063,95,18330,129,10343,7.46564345829575e-11,0.415555031,0.315051027,0.546488708,2.49227387578467e-09,DB0011510019063_,19.81007034,-0.878140228,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,268130,DB00335,10019063,32,8434,31,5434,0.120372234,0.665120187,0.392493564,1.128403359,0.241857833,DB0033510019063_,1.419405194,-0.407787522,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,atenolol,DB00335
,268134,DB01043,10019063,50,1351,121,1289,2.22669915271953e-08,0.394382879,0.275294718,0.557995013,4.62130179464925e-07,DB0104310019063_,14.58741921,-0.930433067,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,memantine,DB01043
,268170,DB01068,10029412,44,13719,26,6814,0.525199146,0.840560383,0.505754821,1.423267094,0.683324319,DB0106810029412_,0.380785687,-0.173686487,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,268171,DB01156,10029412,42,13580,25,6303,0.357315427,0.779791786,0.463868944,1.336329223,0.527020706,DB0115610029412_,0.640515441,-0.248728335,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,268176,DB00051,10044728,35,25696,27,11393,0.037785299,0.57475457,0.337838481,0.987804682,0.101200998,DB0005110044728_,2.290646661,-0.553812164,NA,10044728,Tuberculin test positive,10022891,Investigations,Inv,adalimumab,DB00051
,268198,DB00275,10025482,61,1999,19,1218,0.009895428,1.95582584,1.145970303,3.48455232,0.035260805,DB0027510025482_,3.344983285,0.670812529,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,olmesartan,DB00275
,268217,DB00601,10029331,39,866,46,865,0.505466989,0.846925553,0.532384383,1.34147386,0.666365919,DB0060110029331_,0.405916332,-0.166142483,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,linezolid,DB00601
,268221,DB00864,10029331,25,6844,31,8361,1,0.985204822,0.557162898,1.726045559,1,DB0086410029331_,0,-0.014905718,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,tacrolimus,DB00864
,268325,DB00327,10027175,55,6083,20,4242,0.012872637,1.917602415,1.129139156,3.383111114,0.043524216,DB0032710027175_,3.134437802,0.651075664,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,268350,DB00413,10037660,37,2162,17,1190,0.570240995,1.197871591,0.65455953,2.279085631,0.720874573,DB0041310037660_,0.327290119,0.180546308,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,pramipexole,DB00413
,268393,DB00958,10061188,34,4560,41,2544,0.000999637,0.4626897,0.284032705,0.749385582,0.005499836,DB0095810061188_,5.20303705,-0.770698644,NA,10061188,Haematotoxicity,10005329,Blood and lymphatic system disorders,Blood,carboplatin,DB00958
,268470,DB09570,10040047,28,3873,54,3881,0.00523287,0.519634708,0.316208509,0.836960265,0.02122132,DB0957010040047_,3.852748944,-0.654629198,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ixazomib,DB09570
,268472,DB00650,10046571,34,2097,19,1995,0.071875802,1.702210756,0.940192791,3.170289763,0.164562122,DB0065010046571_,1.804467138,0.531927851,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,leucovorin,DB00650
,268536,DB00924,10016825,58,10104,13,4238,0.037232311,1.871267653,1.01204672,3.726774422,0.100020573,DB0092410016825_,2.302379388,0.62661609,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,cyclobenzaprine,DB00924
,268571,DB00804,10037844,86,2914,20,879,0.349853108,1.296990974,0.784805178,2.241721648,0.519439034,DB0080410037844_,0.65500583,0.260046946,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dicyclomine,DB00804
,268623,DB14513,10005654,44,7133,15,3549,0.266884088,1.459422116,0.795389494,2.827364819,0.429107429,DB1451310005654_,0.846047973,0.378040546,NA,10005654,Blood magnesium decreased,10022891,Investigations,Inv,magnesium,DB14513
,268657,DB00425,10011781,45,12650,10,7474,0.003083816,2.658612951,1.319847276,5.919489444,0.0138348,DB0042510011781_,4.280568147,0.97780454,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,zolpidem,DB00425
,268714,DB00381,10017533,69,29291,29,22858,0.004260974,1.85672152,1.186738259,2.973255806,0.01798762,DB0038110017533_,4.01807155,0.618812309,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,268716,DB00175,10042674,64,8067,25,6081,0.004975271,1.92966041,1.196596677,3.20207495,0.020379461,DB0017510042674_,3.89322772,0.657344034,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,pravastatin,DB00175
,268728,DB00586,10038435,43,7066,22,2783,0.334019647,0.76982168,0.449471763,1.354026862,0.50306431,DB0058610038435_,0.687037264,-0.261596375,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,diclofenac,DB00586
,268744,DB01062,10069339,64,4422,41,1704,0.015381244,0.601569703,0.398447358,0.917180775,0.050285573,DB0106210069339_,2.99003707,-0.508212869,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,oxybutynin,DB01062
,268745,DB01220,10069339,16,1278,39,1097,0.000312943,0.352297495,0.182702537,0.649379314,0.002089334,DB0122010069339_,6.170909897,-1.043279304,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,rifaximin,DB01220
,268747,DB01610,10069339,50,891,66,1152,0.923723633,0.979499451,0.657190157,1.452316436,0.966829343,DB0161010069339_,0.03373328,-0.020713602,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,valganciclovir,DB01610
,268766,DB00709,10059866,57,583,12,627,1.63853032640041e-08,5.102262148,2.673385485,10.55849812,3.49868152960477e-07,DB0070910059866_,14.86570946,1.629684,female,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,lamivudine,DB00709
,268786,DB06228,10022972,28,15884,45,16031,0.060323496,0.627993164,0.377021197,1.029397852,0.144047521,DB0622810022972_,1.937612025,-0.465225998,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,rivaroxaban,DB06228
,268805,DB00904,10021114,42,23027,20,14436,0.3612468,1.316514623,0.755544664,2.368048463,0.531135346,DB0090410021114_,0.632738401,0.274987807,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,ondansetron,DB00904
,268810,DB09037,10043554,30,2496,22,2813,0.127484692,1.536685157,0.85473137,2.803741232,0.252044763,DB0903710043554_,1.378148576,0.429627601,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,pembrolizumab,DB09037
,268974,DB00951,10037660,31,621,31,534,0.602237276,0.860011979,0.498322309,1.484151404,0.746309613,DB0095110037660_,0.292614734,-0.150808961,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,isoniazid,DB00951
,269020,DB00480,10061598,63,67365,46,67616,0.103930114,1.374659523,0.924996073,2.056651044,0.216913058,DB0048010061598_,1.52825866,0.318206081,NA,10061598,Immunodeficiency,10021428,Immune system disorders,Immun,lenalidomide,DB00480
,269063,DB06273,10020937,56,5039,7,1403,0.044667784,2.227129975,1.009706898,5.8064958,0.114921225,DB0627310020937_,2.163508383,0.80071375,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,tocilizumab,DB06273
,269080,DB00904,10011781,76,22993,26,14430,0.007748391,1.834440908,1.160877273,2.985643246,0.029029182,DB0090410011781_,3.539453684,0.606739753,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,ondansetron,DB00904
,269097,DB09035,10054889,29,4697,35,6655,0.527228591,1.173949936,0.691148101,1.980059044,0.684879755,DB0903510054889_,0.378511996,0.160374077,NA,10054889,Transaminases increased,10022891,Investigations,Inv,nivolumab,DB09035
,269166,DB00480,10021519,56,67372,70,67592,0.24657507,0.802615273,0.554401329,1.157283088,0.405668959,DB0048010021519_,0.902217824,-0.219879792,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,269195,DB09570,10016256,281,3620,271,3664,0.596443299,1.04951666,0.879322799,1.252725165,0.741849814,DB0957010016256_,0.298608464,0.048329735,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,269196,DB09570,10025482,100,3801,84,3851,0.23258439,1.20610544,0.890084485,1.637738918,0.389034375,DB0957010025482_,0.944087572,0.187396524,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,269197,DB09570,10037660,53,3848,53,3882,1,1.008835249,0.674322788,1.509275253,1,DB0957010037660_,0,0.008796447,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,269237,DB00115,10020765,49,18376,40,10432,0.097416005,0.695464849,0.448302437,1.084505214,0.206999167,DB0011510020765_,1.57504051,-0.36317481,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,269239,DB00193,10020765,33,19287,26,8676,0.034702498,0.570954243,0.330932053,0.994715056,0.094848202,DB0019310020765_,2.355477544,-0.560446207,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,269242,DB00787,10020765,28,16972,34,17214,0.526073502,0.835277365,0.487695645,1.419925089,0.683987931,DB0078710020765_,0.379815006,-0.179991435,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,269247,DB01104,10020765,42,15421,26,7260,0.297773467,0.760482699,0.45513454,1.29311193,0.463683387,DB0110410020765_,0.768553315,-0.273801917,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,269253,DB06403,10069339,101,21370,57,6604,0.000467609,0.547607108,0.391442512,0.772523333,0.002920733,DB0640310069339_,5.835920667,-0.602197205,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ambrisentan,DB06403
,269266,DB00661,10017577,48,3480,11,1584,0.046539969,1.985977637,1.013652744,4.252422825,0.118577335,DB0066110017577_,2.132189919,0.686111305,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,verapamil,DB00661
,269325,DB00734,10035664,44,4006,34,4868,0.051974825,1.572481609,0.980295234,2.542202267,0.128749249,DB0073410035664_,2.04988857,0.452655014,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,risperidone,DB00734
,269336,DB00904,10062244,41,23028,13,14443,0.034890118,1.978033079,1.038631678,4.024839811,0.095207675,DB0090410062244_,2.351694726,0.682102956,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,269373,DB06228,10056819,38,15874,16,16060,0.002532243,2.402886407,1.307586653,4.617338522,0.011778447,DB0622810056819_,4.441483956,0.876670684,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,269412,DB00635,10034839,41,33012,16,23778,0.043021992,1.845699425,1.013251812,3.524282928,0.111725838,DB0063510034839_,2.191707284,0.612858298,NA,10034839,Pharyngitis streptococcal,10021881,Infections and infestations,Infec,prednisone,DB00635
,269434,DB01041,10019211,37,3008,22,3096,0.048989435,1.730856638,0.991915214,3.088219806,0.12310586,DB0104110019211_,2.09471064,0.548616453,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,thalidomide,DB01041
,269435,DB00051,10016807,37,25694,16,11404,1,1.026396783,0.55682261,1.977041744,1,DB0005110016807_,0,0.0260544,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,adalimumab,DB00051
,269451,DB00231,10047942,47,3249,33,2106,0.730669253,0.923207648,0.576952234,1.492738195,0.843350648,DB0023110047942_,0.170372454,-0.079901099,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,temazepam,DB00231
,269454,DB00997,10007559,73,5258,15,3499,5.15977316347631e-06,3.238201166,1.837014575,6.089303122,6.09059007076802e-05,DB0099710007559_,9.706180496,1.17501798,female,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,doxorubicin,DB00997
,269497,DB09027,10037087,114,5065,109,7043,0.006084733,1.454236854,1.105648409,1.913589318,0.023935529,DB0902710037087_,3.732391342,0.374481264,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ledipasvir,DB09027
,269498,DB09027,10037844,143,5036,146,7006,0.009514341,1.362543393,1.071115801,1.732926035,0.034215213,DB0902710037844_,3.375084924,0.309353095,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ledipasvir,DB09027
,269500,DB00318,10012735,104,4179,36,1803,0.304788696,1.246322632,0.841908989,1.882914353,0.471566957,DB0031810012735_,0.751694178,0.220197321,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,codeine,DB00318
,269510,DB09079,10028813,113,544,57,820,6.94955535138498e-11,2.986087014,2.111406361,4.260879405,2.33144942452015e-09,DB0907910028813_,19.87677569,1.093963839,female,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,nintedanib,DB09079
,269548,DB00787,10048865,31,16969,37,17211,0.544932177,0.849791379,0.509577582,1.408359539,0.699818848,DB0078710048865_,0.356933766,-0.162764396,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,acyclovir,DB00787
,269629,DB00213,10043417,35,18860,16,13405,0.156288155,1.554772606,0.837770329,3.009789904,0.2924284,DB0021310043417_,1.229535428,0.441329301,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,269651,DB11074,10037844,42,1218,14,854,0.018375305,2.102765843,1.117317531,4.196135293,0.057791792,DB1107410037844_,2.850908524,0.743253546,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dimethicone,DB11074
,269666,DB06589,10011224,13,2017,38,2615,0.010146453,0.443609263,0.216240903,0.854090518,0.035982126,DB0658910011224_,3.32473297,-0.812811142,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pazopanib,DB06589
,269732,DB06724,10016807,43,7886,17,3902,0.493057274,1.251494861,0.698028286,2.343910917,0.655851033,DB0672410016807_,0.4218216,0.224338726,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,calcium carbonate,DB06724
,269747,DB00399,10017944,32,6960,21,4977,0.782310886,1.089667621,0.60842339,1.990789477,0.881493586,DB0039910017944_,0.126137553,0.085872715,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,zoledronic acid,DB00399
,269751,DB00190,10047700,75,3222,55,4619,0.000206073,1.95475,1.357724424,2.829352325,0.001477265,DB0019010047700_,6.517563061,0.670262308,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,carbidopa,DB00190
,269816,DB00455,10006784,48,9353,26,5092,1,1.005090605,0.6103779,1.689951399,1,DB0045510006784_,0,0.005077692,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,269820,DB01098,10006784,49,8100,22,7187,0.008311081,1.97609283,1.171183011,3.435797838,0.030699376,DB0109810006784_,3.483512963,0.681121577,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,269850,DB00437,10040753,79,6842,61,11485,6.11717856470376e-06,2.173863485,1.534589168,3.09196748,7.05064847942287e-05,DB0043710040753_,9.559805869,0.776505993,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,allopurinol,DB00437
,269886,DB00374,10051301,44,17672,29,5695,0.003823434,0.488947618,0.298862349,0.811206797,0.016447205,DB0037410051301_,4.107599706,-0.715499916,NA,10051301,Exercise tolerance decreased,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,269952,DB11133,10011224,47,2384,32,1542,0.817132153,0.950032395,0.590556774,1.545880545,0.902147121,DB1113310011224_,0.102977667,-0.051259195,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omega-3 fatty acids,DB11133
,269955,DB00404,10012373,64,19828,42,9820,0.178630383,0.754717795,0.503109537,1.14268595,0.322169591,DB0040410012373_,1.132677193,-0.281411381,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,270187,DB01240,10028391,93,5658,22,1554,0.647056348,1.161018882,0.720516873,1.948020441,0.782313016,DB0124010028391_,0.245500343,0.149297967,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,epoprostenol,DB01240
,270188,DB01592,10028391,42,6234,12,3055,0.110029138,1.715101608,0.88488287,3.583895517,0.226105535,DB0159210028391_,1.486753421,0.539472326,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,iron,DB01592
,270311,DB06262,10011906,251,3549,636,3678,8.93181139860888e-33,0.409040693,0.349467029,0.477671374,2.35952424736115e-30,DB0626210011906_,68.21909278,-0.893940634,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,270336,DB00285,10012373,50,10901,7,3711,0.021641953,2.431656918,1.095867225,6.362629628,0.065817278,DB0028510012373_,2.720872889,0.888572884,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,venlafaxine,DB00285
,270446,DB00152,10003549,22,809,40,824,0.037657022,0.560387988,0.314191158,0.975718588,0.100924274,DB0015210003549_,2.293384803,-0.5791259,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,thiamine,DB00152
,270517,DB00213,10056819,65,18830,47,13374,0.923794343,0.982255461,0.664128641,1.462452933,0.966829343,DB0021310056819_,0.03373328,-0.01790386,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,pantoprazole,DB00213
,270541,DB06724,10038153,49,7880,32,3887,0.236124131,0.755374372,0.473265187,1.22084965,0.393362957,DB0672410038153_,0.933022537,-0.280541796,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,calcium carbonate,DB06724
,270545,DB01222,10047942,54,9220,42,5363,0.167991755,0.747896175,0.489713105,1.149034195,0.308141192,DB0122210047942_,1.177197186,-0.290491114,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,budesonide,DB01222
,270559,DB09038,10018484,34,2214,39,2502,1,0.985200907,0.600964672,1.607975124,1,DB0903810018484_,0,-0.014909692,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,empagliflozin,DB09038
,270570,DB00019,10062355,107,18905,43,9486,0.25894694,1.248547689,0.867940263,1.824374638,0.420019767,DB0001910062355_,0.867453504,0.221981027,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,270768,DB00190,10007515,15,3282,35,4639,0.113788261,0.60580905,0.306858392,1.140572237,0.231836141,DB0019010007515_,1.461724445,-0.501190442,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,carbidopa,DB00190
,270777,DB00190,10012174,35,3262,59,4615,0.461379483,0.839303599,0.534725258,1.299893878,0.628664915,DB0019010012174_,0.46415689,-0.175182779,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,carbidopa,DB00190
,270788,DB00620,10040047,45,4783,42,3090,0.097686658,0.69223446,0.443200738,1.083077521,0.2074416,DB0062010040047_,1.572905426,-0.367830566,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,triamcinolone,DB00620
,270805,DB01142,10012378,39,1701,15,769,0.657967864,1.175340982,0.628979839,2.309801518,0.790957687,DB0114210012378_,0.234510806,0.161558303,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,doxepin,DB01142
,270815,DB01142,10070863,217,1523,103,681,0.651143768,0.942064187,0.728423505,1.224051497,0.785610665,DB0114210070863_,0.241293947,-0.059681868,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,doxepin,DB01142
,270890,DB00230,10039227,48,19626,6,8645,0.001038502,3.523413961,1.505042547,10.08084337,0.005686289,DB0023010039227_,5.169697399,1.259430395,female,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,270903,DB00829,10007882,35,8017,25,4429,0.345284128,0.773466406,0.449239641,1.350032035,0.514705002,DB0082910007882_,0.664161354,-0.256873042,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,diazepam,DB00829
,270937,DB08877,10019974,33,3256,26,3203,0.43405845,1.248525881,0.722360225,2.179095596,0.602578766,DB0887710019974_,0.506536891,0.22196356,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,ruxolitinib,DB08877
,270945,DB06403,10049438,75,21396,37,6624,0.025315271,0.627560477,0.417462686,0.958195827,0.074195643,DB0640310049438_,2.601049844,-0.465915235,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,271033,DB01409,10076309,44,5987,24,3942,0.534440545,1.207066889,0.716832704,2.079003688,0.691005466,DB0140910076309_,0.369607546,0.188193358,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tiotropium,DB01409
,271070,DB09053,10061024,18,2267,40,4012,0.493001162,0.796389853,0.428694291,1.425499661,0.655851033,DB0905310061024_,0.4218216,-0.227666448,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,ibrutinib,DB09053
,271099,DB00190,10013700,49,3248,16,4658,3.24412738114052e-08,4.391182967,2.449626729,8.288606658,6.51427717442923e-07,DB0019010013700_,14.24409939,1.479598659,female,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,carbidopa,DB00190
,271111,DB00656,10013654,240,11773,259,6360,3.988248002216e-14,0.500596124,0.417079198,0.600710158,2.14817825283294e-12,DB0065610013654_,26.86640096,-0.691955642,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,271118,DB00959,10047924,69,8009,24,4978,0.013542011,1.786882991,1.106958364,2.97823285,0.045321079,DB0095910047924_,3.093983033,0.580472756,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,271121,DB00959,10051118,59,8019,41,4961,0.605861922,0.890271086,0.586629587,1.362564761,0.748904541,DB0095910051118_,0.289143752,-0.116229272,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,271133,DB00051,10061822,424,25307,84,11336,2.2562031978082e-13,2.260984909,1.783344618,2.895647215,1.10539237752821e-11,DB0005110061822_,25.22823566,0.815800519,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,271139,DB09038,10012174,54,2194,65,2476,0.780470166,0.93754266,0.63808347,1.372861604,0.880475612,DB0903810012174_,0.12729305,-0.064493018,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,empagliflozin,DB09038
,271211,DB00193,10010144,853,18467,321,8381,0.005039106,1.205959604,1.056636542,1.3790472,0.020591201,DB0019310010144_,3.88289142,0.187275602,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,271212,DB00246,10010144,129,945,61,640,0.027994401,1.431931993,1.029693473,2.008391437,0.080212791,DB0024610010144_,2.523072283,0.359024576,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,ziprasidone,DB00246
,271214,DB00656,10010144,945,11068,411,6208,2.81840694135774e-05,1.289618774,1.142503338,1.457593676,0.000268753,DB0065610010144_,8.221716979,0.254346651,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,271216,DB00843,10010144,78,2116,23,2150,2.58736481954368e-08,3.445166662,2.130836117,5.771879642,5.29252017756463e-07,DB0084310010144_,14.45180111,1.236972281,female,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,donepezil,DB00843
,271417,DB00678,10016326,37,15562,13,10711,0.04263855,1.958894011,1.017107975,4.018267115,0.110998742,DB0067810016326_,2.198236414,0.672380034,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,271535,DB00572,10003239,62,2840,24,2102,0.00786577,1.911787874,1.1715999,3.214176939,0.02937858,DB0057210003239_,3.527489438,0.648038864,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,atropine,DB00572
,271537,DB08893,10003239,49,2036,14,1044,0.058954065,1.794395672,0.969438458,3.53641396,0.141497293,DB0889310003239_,1.955474696,0.584668293,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,mirabegron,DB08893
,271538,DB09033,10003239,164,2460,84,1585,0.107147426,1.257870394,0.953491179,1.669294646,0.221840029,DB0903310003239_,1.505798748,0.229420127,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,vedolizumab,DB09033
,271542,DB09033,10003988,39,2585,30,1639,0.45602584,0.82430023,0.496841126,1.379900607,0.623389239,DB0903310003988_,0.472584173,-0.193220459,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,vedolizumab,DB09033
,271556,DB09033,10033425,57,2567,19,1650,0.012414799,1.928047477,1.125101794,3.445089013,0.04228625,DB0903310033425_,3.163293294,0.656507821,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,vedolizumab,DB09033
,271561,DB09033,10037844,93,2531,46,1623,0.15834573,1.29636065,0.895690371,1.898869719,0.295279877,DB0903310037844_,1.219831636,0.259560838,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,vedolizumab,DB09033
,271570,DB09033,10047895,30,2594,29,1640,0.107982409,0.654117312,0.377782283,1.133996997,0.223054769,DB0903310047895_,1.500337937,-0.424468567,NA,10047895,Weight decreased,10022891,Investigations,Inv,vedolizumab,DB09033
,271579,DB00668,10039906,70,10021,38,4265,0.245742381,0.783999269,0.520001106,1.19838814,0.404631722,DB0066810039906_,0.904777954,-0.243347191,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,epinephrine,DB00668
,271611,DB00921,10010144,65,5780,39,4864,0.113088096,1.402491472,0.926917406,2.146933215,0.230696206,DB0092110010144_,1.46665356,0.338250278,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,271621,DB06791,10053762,42,737,48,490,0.014400882,0.582015314,0.369073171,0.914731689,0.04767345,DB0679110053762_,3.043380643,-0.541258519,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lanreotide,DB06791
,271622,DB01281,10054112,84,8848,24,1774,0.15271973,0.701767519,0.43990281,1.158856734,0.287748691,DB0128110054112_,1.245667781,-0.354153099,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,abatacept,DB01281
,271660,DB00152,10011906,32,799,56,808,0.015868299,0.578052331,0.358100335,0.91927776,0.051512688,DB0015210011906_,2.965927131,-0.548090876,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,thiamine,DB00152
,271708,DB00327,10013654,112,6026,143,4119,1.11487865865267e-06,0.535406206,0.412928862,0.692739984,1.57509193994547e-05,DB0032710013654_,11.05861182,-0.624729557,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,hydromorphone,DB00327
,271850,DB01270,10008190,39,1219,26,943,0.612722453,1.160291641,0.683114899,2.000426119,0.754563797,DB0127010008190_,0.281615449,0.148671388,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,ranibizumab,DB01270
,271852,DB00710,10012735,117,2289,10,191,0.865258238,0.976283349,0.501308116,2.124807539,0.938565236,DB0071010012735_,0.063402915,-0.024002418,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ibandronate,DB00710
,271893,DB00635,10021114,55,32998,24,23770,0.040095172,1.650776481,1.004539707,2.789400747,0.105866559,DB0063510021114_,2.24557586,0.501245772,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,prednisone,DB00635
,271896,DB00635,10023003,41,33012,20,23774,0.155965002,1.476321547,0.845083872,2.660614964,0.29211487,DB0063510023003_,1.230608165,0.389553553,NA,10023003,Irritable bowel syndrome,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,271942,DB06273,10025482,124,4971,18,1392,0.007215233,1.9288245,1.166275738,3.373822554,0.027422431,DB0627310025482_,3.596393947,0.65691075,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,271952,DB00563,10044728,56,46590,27,15321,0.12553482,0.682058733,0.423515395,1.123536043,0.249399701,DB0056310044728_,1.388698447,-0.382639506,NA,10044728,Tuberculin test positive,10022891,Investigations,Inv,methotrexate,DB00563
,271972,DB00656,10060933,41,11972,16,6603,0.269185299,1.4132884,0.775379373,2.70012403,0.431698327,DB0065610060933_,0.840028251,0.345919188,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,272023,DB01225,10000060,33,5011,28,4612,0.797904928,1.084684105,0.634507828,1.866392702,0.890778357,DB0122510000060_,0.11565964,0.081288798,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,272092,DB08868,10008531,45,9157,22,2489,0.035026919,0.556015857,0.326280015,0.974242264,0.095459724,DB0886810008531_,2.349050863,-0.586958466,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,272120,DB00472,10000060,57,10702,16,4296,0.242796993,1.429968405,0.80881327,2.671247806,0.401038046,DB0047210000060_,0.913698978,0.35765235,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,fluoxetine,DB00472
,272139,DB00181,10043417,38,9818,23,5848,1,0.984097064,0.570770639,1.732014974,1,DB0018110043417_,0,-0.016030744,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,272140,DB00182,10043417,46,5148,14,2838,0.057199493,1.811233761,0.976309288,3.57407335,0.138181946,DB0018210043417_,1.979184013,0.594008249,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,272143,DB00563,10043417,66,46580,25,15323,0.544237285,0.868479196,0.540382293,1.437090137,0.699285185,DB0056310043417_,0.35769663,-0.141011648,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,272217,DB00169,10043417,102,38589,32,18143,0.050997742,1.498624713,0.998283369,2.305664662,0.126896924,DB0016910043417_,2.064380141,0.404547829,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,272218,DB00331,10043417,56,24890,42,20710,0.684804881,1.109380987,0.730054124,1.69742815,0.809622937,DB0033110043417_,0.21118665,0.103802191,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,272221,DB09072,10043417,108,6363,40,2495,0.853789749,1.058691749,0.727843681,1.567094393,0.928788973,DB0907210043417_,0.073873721,0.057033947,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,272227,DB00331,10051076,47,24899,53,20699,0.132381307,0.737217708,0.486758415,1.113442477,0.259116656,DB0033110051076_,1.35047691,-0.304872033,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,272253,DB00864,10001053,23,6846,54,8338,0.007974254,0.518779075,0.303547605,0.860759195,0.029711995,DB0086410001053_,3.516204437,-0.656277161,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tacrolimus,DB00864
,272254,DB00887,10001053,38,2303,28,1787,0.900742972,1.05306456,0.626755663,1.789033379,0.956763316,DB0088710001053_,0.044199237,0.051704542,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bumetanide,DB00887
,272341,DB00030,10040047,32,2174,31,1790,0.52656574,0.849963818,0.50009798,1.446383908,0.684323279,DB0003010040047_,0.379324843,-0.162561497,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,insulin human,DB00030
,272351,DB00864,10040070,103,6766,115,8277,0.53732212,1.095664235,0.829903014,1.445013951,0.693484823,DB0086410040070_,0.366025923,0.091360787,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,272354,DB00959,10040070,51,8027,76,4926,8.29823884384663e-07,0.411837074,0.282497848,0.596106206,1.2165042276102e-05,DB0095910040070_,11.31694411,-0.887127459,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,272374,DB00586,10003285,63,7046,12,2793,0.0197381,2.080945896,1.109692381,4.246159256,0.06115949,DB0058610003285_,2.794270242,0.732822548,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,272401,DB00341,10076309,106,11299,50,5018,0.727794674,0.941518005,0.665340207,1.347902508,0.84112309,DB0034110076309_,0.173017268,-0.060261808,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,272404,DB00586,10076309,82,7027,28,2777,0.59459519,1.157320272,0.74353116,1.850930942,0.740462148,DB0058610076309_,0.300480763,0.146107223,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,diclofenac,DB00586
,272405,DB00695,10076309,212,27837,134,20394,0.190146826,1.15904587,0.928479836,1.451077699,0.336736352,DB0069510076309_,1.088454992,0.147597141,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,272408,DB00678,10060795,52,15547,37,10687,0.91408097,0.966056766,0.621213258,1.515939352,0.961536643,DB0067810060795_,0.039222604,-0.034532683,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,losartan,DB00678
,272418,DB09037,10021097,41,2485,35,2800,0.248104202,1.319844008,0.817207692,2.14200844,0.407474083,DB0903710021097_,0.897777949,0.277513554,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,pembrolizumab,DB09037
,272510,DB05676,10024670,31,47098,19,25310,0.658105041,0.876801081,0.479796833,1.642960326,0.7911045,DB0567610024670_,0.234325209,-0.13147513,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,apremilast,DB05676
,272570,DB01233,10064848,34,3387,17,1709,1,1.00915095,0.54652349,1.932078345,1,DB0123310064848_,0,0.009109334,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,metoclopramide,DB01233
,272589,DB01233,10017577,38,3383,12,1714,0.176261025,1.604259445,0.818113016,3.380973236,0.31903464,DB0123310017577_,1.142455591,0.472662245,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,metoclopramide,DB01233
,272599,DB00211,10003658,39,1397,26,1605,0.033056349,1.723010993,1.016780437,2.964327133,0.091418395,DB0021110003658_,2.392308565,0.544073338,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,midodrine,DB00211
,272629,DB06643,10035226,33,52388,25,7490,7.14023006041237e-09,0.188729257,0.108818518,0.3312263,1.65576486226678e-07,DB0664310035226_,15.6138326,-1.667441794,male,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,denosumab,DB06643
,272640,DB00704,10038743,33,4323,50,5144,0.319569241,0.785364015,0.48914871,1.245958837,0.487772272,DB0070410038743_,0.717906638,-0.241607955,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,272732,DB11750,10011906,21,2479,32,1481,0.000886473,0.392149721,0.214024834,0.704338898,0.004991098,DB1175010011906_,5.300099328,-0.93611157,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,clobetasol,DB11750
,272770,DB01234,10043521,56,31569,39,32849,0.063994256,1.494099014,0.974947999,2.31038148,0.150637983,DB0123410043521_,1.892875784,0.401523359,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,272806,DB00472,10019303,48,10711,13,4299,0.2558388,1.481979033,0.789274758,2.984682149,0.416584969,DB0047210019303_,0.87566483,0.393378379,NA,10019303,Heart rate increased,10022891,Investigations,Inv,fluoxetine,DB00472
,272821,DB00455,10037162,44,9357,11,5107,0.016301341,2.183074756,1.108201891,4.691777417,0.052596911,DB0045510037162_,2.945097879,0.780734322,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,272865,DB00047,10068319,38,9247,24,8494,0.162358757,1.454364715,0.849297873,2.536912396,0.300545788,DB0004710068319_,1.202155164,0.374569183,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,272868,DB00956,10068319,52,5762,27,3440,0.640676767,1.149817736,0.707530387,1.907882141,0.777586407,DB0095610068319_,0.251560507,0.139603439,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrocodone,DB00956
,272883,DB00335,10039906,48,8418,30,5435,1,1.033024433,0.640405035,1.690880652,1,DB0033510039906_,0,0.032490842,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,273023,DB00678,10018836,46,15553,34,10690,0.819883372,0.929916381,0.583622087,1.494995771,0.904083334,DB0067810018836_,0.100833739,-0.07266061,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,273058,DB00531,10029350,85,7167,130,6386,0.000108532,0.582624321,0.43698539,0.773409625,0.000855533,DB0053110029350_,7.063786096,-0.54021269,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,273070,DB00213,10013754,37,18858,17,13404,0.166481754,1.546982371,0.849151967,2.931104193,0.306108418,DB0021310013754_,1.183815932,0.436306176,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,273138,DB09153,10038683,32,7767,19,5680,0.570372169,1.231642417,0.67641522,2.302400139,0.72095008,DB0915310038683_,0.327185382,0.208348577,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,273140,DB00480,10012431,32,67396,21,67641,0.132957037,1.529335668,0.854994675,2.790886531,0.259892594,DB0048010012431_,1.347486835,0.424833437,NA,10012431,Dermatitis,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,273156,DB00904,10039906,222,22847,136,14320,0.8700298,1.023123613,0.821909268,1.277380343,0.942244012,DB0090410039906_,0.059491002,0.022860314,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,273158,DB00658,10053762,42,1261,23,1373,0.0081876,1.987764224,1.160849425,3.483618386,0.030369163,DB0065810053762_,3.494327555,0.687010501,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sevelamer,DB00658
,273163,DB01118,10022611,21,3042,44,4665,0.254066166,0.731940964,0.412530787,1.260443839,0.414661855,DB0111810022611_,0.880291898,-0.312055418,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,273164,DB01118,10037383,12,3051,67,4642,3.99571225739887e-06,0.272539556,0.133935477,0.50914302,4.85450874442936e-05,DB0111810037383_,9.933017554,-1.299971515,male,10037383,Pulmonary fibrosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,273182,DB09035,10016173,48,4678,71,6619,0.851935597,0.956564695,0.647727345,1.402107889,0.927294854,DB0903510016173_,0.075483691,-0.044406855,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,nivolumab,DB09035
,273192,DB00203,10013969,59,13819,14,8924,0.000413181,2.721363989,1.499976689,5.280800455,0.002632199,DB0020310013969_,5.939935491,1.001133221,female,10013969,Dyspnoea at rest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,273207,DB01222,10044390,31,9243,20,5385,0.771625429,0.903043209,0.498002682,1.673407808,0.875014307,DB0122210044390_,0.133515042,-0.101984876,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,budesonide,DB01222
,273247,DB00864,10010305,65,6804,65,8327,0.251450516,1.223817836,0.85290455,1.756082661,0.411439239,DB0086410010305_,0.888093926,0.201975346,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,tacrolimus,DB00864
,273283,DB00999,10051792,54,21376,24,12215,0.34651269,1.285737165,0.780847287,2.175951606,0.515951173,DB0099910051792_,0.661743144,0.251332223,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,273345,DB01020,10061428,31,1782,40,1838,0.401879231,0.799404473,0.481160649,1.316914207,0.571643249,DB0102010061428_,0.559240173,-0.223888237,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,isosorbide mononitrate,DB01020
,273399,DB08931,10036790,147,6430,52,2394,0.809037174,1.052495903,0.759391917,1.47860634,0.897015317,DB0893110036790_,0.108682342,0.051164394,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,273433,DB06674,10037087,76,4430,23,1467,0.814629854,1.094222078,0.675725784,1.835481675,0.900576019,DB0667410037087_,0.104720699,0.090043679,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,golimumab,DB06674
,273458,DB06605,10022000,140,13933,84,12949,0.00155418,1.548929538,1.172158389,2.057357964,0.007917746,DB0660510022000_,4.838648689,0.437564072,NA,10022000,Influenza,10021881,Infections and infestations,Infec,apixaban,DB06605
,273516,DB08868,10028836,84,9118,16,2495,0.220586388,1.436527417,0.833265233,2.632673055,0.374192528,DB0886810028836_,0.982984833,0.362228685,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,fingolimod,DB08868
,273615,DB06228,10019974,41,15871,24,16052,0.034615768,1.727775716,1.01896286,2.991118931,0.094660369,DB0622810019974_,2.357459854,0.546834868,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,rivaroxaban,DB06228
,273639,DB00678,10022998,33,15566,22,10702,1,1.031287472,0.583144339,1.857900149,1,DB0067810022998_,0,0.030807994,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,losartan,DB00678
,273720,DB00684,10022000,40,2752,44,2304,0.225658247,0.761144993,0.481555264,1.199947654,0.380463567,DB0068410022000_,0.966364856,-0.272931409,NA,10022000,Influenza,10021881,Infections and infestations,Infec,tobramycin,DB00684
,273735,DB01104,10061224,41,15422,11,7275,0.102380316,1.758222431,0.886928289,3.795603607,0.214564393,DB0110410061224_,1.539145386,0.564303316,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,273798,DB01268,10000060,24,2119,42,3088,0.529474551,0.83277906,0.480807443,1.412127998,0.686779272,DB0126810000060_,0.37574233,-0.182986906,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,sunitinib,DB01268
,273829,DB00281,10076309,81,11377,36,5635,0.623378635,1.114407717,0.742752331,1.701688641,0.763455716,DB0028110076309_,0.269900157,0.108323068,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lidocaine,DB00281
,273832,DB00448,10076309,34,5111,16,3108,0.465519587,1.292174113,0.692690423,2.511280126,0.632314471,DB0044810076309_,0.458368428,0.256326158,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lansoprazole,DB00448
,273833,DB00829,10076309,56,7996,34,4420,0.660101099,0.910464152,0.583192587,1.4404479,0.792471049,DB0082910076309_,0.232599305,-0.093800752,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,273834,DB00863,10076309,96,10577,43,5797,0.286348135,1.223556343,0.844184755,1.799219282,0.451089913,DB0086310076309_,0.796088597,0.201761654,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,273836,DB08865,10076309,31,1180,29,942,0.598930811,0.85342521,0.493651016,1.479223202,0.7436826,DB0886510076309_,0.296140948,-0.158497369,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,crizotinib,DB08865
,273839,DB08931,10028810,253,6324,71,2375,0.035482015,1.33816223,1.020021947,1.77435034,0.096452221,DB0893110028810_,2.338707511,0.291297202,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,riociguat,DB08931
,273854,DB00065,10037087,207,9257,86,4871,0.071492425,1.266560952,0.977810958,1.652289716,0.163869927,DB0006510037087_,1.808682294,0.236305316,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,infliximab,DB00065
,273867,DB00186,10048393,65,16836,20,9988,0.00938398,1.928025706,1.152110512,3.362783288,0.033835103,DB0018610048393_,3.386256462,0.656496529,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,273886,DB06605,10025482,370,13703,178,12855,9.76128353652838e-14,1.949960367,1.62355479,2.348895384,5.01613563553565e-12,DB0660510025482_,26.01836127,0.667809048,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,273888,DB06605,10061822,61,14012,64,12969,0.530211513,0.882182783,0.610364154,1.273964468,0.687294272,DB0660510061822_,0.374992734,-0.125356008,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,273905,DB00193,10011781,83,19237,9,8693,2.2141963171845e-06,4.167668251,2.091272659,9.435871897,2.90130359906255e-05,DB0019310011781_,10.44776531,1.427356707,female,10011781,Cystitis,10021881,Infections and infestations,Infec,tramadol,DB00193
,273910,DB00331,10018870,31,24915,32,20720,0.447779011,0.805646343,0.475292919,1.363908215,0.615562946,DB0033110018870_,0.485218071,-0.216110414,NA,10018870,Blood urine present,10022891,Investigations,Inv,metformin,DB00331
,273934,DB00065,10039906,38,9426,20,4937,1,0.995151337,0.563960894,1.807138708,1,DB0006510039906_,0,-0.004860456,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,infliximab,DB00065
,273935,DB00678,10039906,91,15508,53,10671,0.350703007,1.181414519,0.832158943,1.692055329,0.520436332,DB0067810039906_,0.653087719,0.166712465,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,losartan,DB00678
,273937,DB00186,10017853,41,16860,19,9989,0.423818385,1.278481749,0.724947713,2.333586597,0.592603997,DB0018610017853_,0.523228899,0.24567324,NA,10017853,Gastritis,10017947,Gastrointestinal disorders,Gastr,lorazepam,DB00186
,273997,DB06403,10062352,63,21408,12,6649,0.134609549,1.630501312,0.870508198,3.3238568,0.26209616,DB0640310062352_,1.339043821,0.488887521,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,274033,DB08910,10033557,63,16681,13,17475,1.07472974487683e-09,5.076364157,2.764355792,10.0593312,2.96580276578347e-08,DB0891010033557_,17.333533,1.624595288,female,10033557,Palpitations,10007541,Cardiac disorders,Card,pomalidomide,DB08910
,274065,DB00471,10038435,71,14118,36,5429,0.193819538,0.758413458,0.500343053,1.167714483,0.34146954,DB0047110038435_,1.0744968,-0.276526583,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,montelukast,DB00471
,274095,DB00433,10017955,59,7597,50,5970,0.699559126,0.927292592,0.624347893,1.381994901,0.819425652,DB0043310017955_,0.199151609,-0.07548613,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,274421,DB01192,10070863,110,658,81,473,0.874426828,0.976217659,0.707988197,1.350151807,0.945603405,DB0119210070863_,0.055932031,-0.024069706,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,oxymorphone,DB01192
,274460,DB08893,10020772,51,2034,26,1032,1,0.995235654,0.605026623,1.673265229,1,DB0889310020772_,0,-0.004775732,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,mirabegron,DB08893
,274521,DB00091,10013950,39,5471,12,2658,0.180072294,1.578881044,0.808287052,3.318020575,0.323914473,DB0009110013950_,1.12727577,0.456716396,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,cyclosporine,DB00091
,274526,DB00959,10013950,73,8005,40,4962,0.560973861,1.131264295,0.757757959,1.710547254,0.713534863,DB0095910013950_,0.337523982,0.123335853,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,274534,DB09076,10013968,110,698,64,546,0.085920495,1.344187676,0.958097293,1.897925749,0.188217368,DB0907610013968_,1.670157771,0.295789872,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,umeclidinium,DB09076
,274537,DB09076,10016256,66,742,28,582,0.007053314,1.848100959,1.153806196,3.028340324,0.026953008,DB0907610016256_,3.613660359,0.614158603,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,umeclidinium,DB09076
,274548,DB00186,10017533,38,16863,13,9995,0.109620189,1.732525665,0.902238649,3.546320302,0.225503164,DB0018610017533_,1.489421089,0.549580266,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,lorazepam,DB00186
,274558,DB01060,10017533,46,8541,16,5065,0.065981683,1.704875357,0.94618057,3.229762282,0.154121437,DB0106010017533_,1.870014436,0.533492004,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,274574,DB00046,10022000,54,5405,37,4655,0.29318253,1.256914814,0.810511551,1.968301593,0.458815583,DB0004610022000_,0.77910693,0.228660158,NA,10022000,Influenza,10021881,Infections and infestations,Infec,insulin lispro,DB00046
,274575,DB00091,10022000,44,5466,17,2653,0.494091624,1.256165429,0.701815289,2.35000181,0.656731731,DB0009110022000_,0.420479668,0.228063771,NA,10022000,Influenza,10021881,Infections and infestations,Infec,cyclosporine,DB00091
,274580,DB00727,10022000,51,3792,29,4144,0.004786735,1.921697454,1.192350858,3.151479905,0.019754959,DB0072710022000_,3.92435072,0.653208886,NA,10022000,Influenza,10021881,Infections and infestations,Infec,nitroglycerin,DB00727
,274582,DB00927,10022000,80,7417,36,4980,0.046014822,1.492021152,0.993112946,2.280897335,0.117512712,DB0092710022000_,2.141208767,0.400131679,NA,10022000,Influenza,10021881,Infections and infestations,Infec,famotidine,DB00927
,274584,DB01060,10022000,90,8497,63,5018,0.313289548,0.843676611,0.603451832,1.185727233,0.480851115,DB0106010022000_,0.732197588,-0.16998602,NA,10022000,Influenza,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,274585,DB01098,10022000,81,8068,50,7159,0.043579567,1.437441584,0.996597179,2.091063161,0.112772723,DB0109810022000_,2.18238079,0.362864856,NA,10022000,Influenza,10021881,Infections and infestations,Infec,rosuvastatin,DB01098
,274586,DB01224,10022000,46,8062,12,5905,0.000748676,2.807483099,1.46199471,5.827607752,0.004326944,DB0122410022000_,5.442893865,1.032288388,female,10022000,Influenza,10021881,Infections and infestations,Infec,quetiapine,DB01224
,274605,DB01224,10022095,43,8065,22,5895,0.207930203,1.428611344,0.834869393,2.510498337,0.358754496,DB0122410022095_,1.025116979,0.356702885,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,274611,DB00727,10025482,116,3727,78,4095,0.001014119,1.633906704,1.211305098,2.213733559,0.005569603,DB0072710025482_,5.190431477,0.490973898,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,nitroglycerin,DB00727
,274613,DB01020,10025482,54,1759,37,1841,0.055669402,1.527310863,0.981384346,2.399996294,0.135481712,DB0102010025482_,1.998918617,0.423508583,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,isosorbide mononitrate,DB01020
,274615,DB09076,10025482,34,774,25,585,1,1.027890078,0.588193373,1.818530751,1,DB0907610025482_,0,0.027508233,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,umeclidinium,DB09076
,274633,DB00243,10037844,39,1215,26,1600,0.007707418,1.974864725,1.164863716,3.39880401,0.028920697,DB0024310037844_,3.543197765,0.680499902,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ranolazine,DB00243
,274767,DB00046,10013971,31,5428,21,4671,0.407465711,1.270286779,0.705858047,2.32937047,0.576920263,DB0004610013971_,0.550051215,0.239242685,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin lispro,DB00046
,274768,DB00047,10013971,42,9243,32,8486,0.484587176,1.204992732,0.741958827,1.974100265,0.64870761,DB0004710013971_,0.432773187,0.186473536,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin glargine,DB00047
,274799,DB09035,10012174,106,4620,163,6527,0.531279193,0.918723726,0.710379623,1.184124734,0.68811834,DB0903510012174_,0.373794451,-0.084769827,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,nivolumab,DB09035
,274802,DB09035,10013950,28,4698,54,6636,0.215666894,0.732435587,0.446000278,1.178843136,0.368235688,DB0903510013950_,0.999032089,-0.311379878,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,nivolumab,DB09035
,274819,DB00904,10039203,52,23017,16,14440,0.01208978,2.038887713,1.145377293,3.827391548,0.041380282,DB0090410039203_,3.184950781,0.712404421,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,274867,DB00390,10024264,31,4114,21,3280,0.579360081,1.17690764,0.653597254,2.159323511,0.728078014,DB0039010024264_,0.317347075,0.162890355,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,digoxin,DB00390
,274871,DB08932,10024264,102,19341,67,6530,3.95712865533958e-05,0.513983303,0.373493448,0.711360054,0.000361057,DB0893210024264_,7.92647377,-0.665564498,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,274879,DB08932,10051301,63,19380,30,6567,0.150815301,0.711604673,0.453348108,1.139882266,0.285060013,DB0893210051301_,1.255055551,-0.340232757,NA,10051301,Exercise tolerance decreased,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,274881,DB00472,10038435,54,10705,25,4287,0.534700222,0.865031287,0.528291132,1.452638513,0.691302007,DB0047210038435_,0.369178493,-0.144989603,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,fluoxetine,DB00472
,274917,DB00682,10036018,41,19418,43,16321,0.325088711,0.801423706,0.509229167,1.259602142,0.493528749,DB0068210036018_,0.706174166,-0.221365501,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,warfarin,DB00682
,274937,DB01281,10043414,53,8879,10,1788,1,1.067296375,0.536042271,2.357594383,1,DB0128110043414_,0,0.065128698,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,274961,DB00471,10051792,51,14138,19,5446,1,1.033988412,0.599369732,1.856335176,1,DB0047110051792_,0,0.033423569,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,275019,DB01088,10028810,58,1371,14,423,0.479586204,1.27804201,0.6954394,2.506935552,0.644556993,DB0108810028810_,0.439192031,0.245329227,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,iloprost,DB01088
,275052,DB00776,10028813,96,1809,39,1300,0.003082592,1.768631946,1.198039085,2.65503119,0.013833015,DB0077610028813_,4.280697133,0.570206336,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,oxcarbazepine,DB00776
,275088,DB00482,10007882,45,8214,24,3047,0.173418175,0.695559227,0.414037492,1.195773926,0.315431232,DB0048210007882_,1.153814587,-0.363039114,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,celecoxib,DB00482
,275091,DB01097,10007882,41,6224,10,1493,1,0.983500622,0.48310295,2.206965019,1,DB0109710007882_,0,-0.016637008,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,leflunomide,DB01097
,275171,DB00158,10016766,57,16758,28,8076,0.908258381,0.981038253,0.613201771,1.603282576,0.958996855,DB0015810016766_,0.041867483,-0.019143826,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,275176,DB01050,10016766,54,18054,34,9337,0.369369245,0.821408609,0.52472829,1.30218497,0.539031828,DB0105010016766_,0.61798066,-0.196734597,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,ibuprofen,DB01050
,275186,DB01050,10017413,47,18061,20,9351,0.52010564,1.216663539,0.706544039,2.169147592,0.67923569,DB0105010017413_,0.386787098,0.196112308,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,ibuprofen,DB01050
,275187,DB01592,10017413,46,6230,49,3018,0.000160978,0.454805462,0.296657668,0.696221093,0.0011985,DB0159210017413_,6.72668444,-0.787885508,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,iron,DB01592
,275191,DB00620,10018884,40,4788,28,3104,0.803443452,0.926134565,0.555999159,1.562228917,0.893659359,DB0062010018884_,0.112430607,-0.076735736,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,triamcinolone,DB00620
,275200,DB00620,10020642,34,4794,17,3115,0.472430788,1.299496552,0.704697016,2.48479776,0.638474867,DB0062010020642_,0.448672967,0.261976922,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,triamcinolone,DB00620
,275205,DB00115,10037423,71,18354,44,10428,0.697574181,0.916807183,0.620248987,1.368500994,0.81818943,DB0011510037423_,0.200661392,-0.086858098,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,275206,DB00126,10037423,43,10128,37,5908,0.103197575,0.677971075,0.426069356,1.083407603,0.21580399,DB0012610037423_,1.533384739,-0.388650654,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,275238,DB00465,10047700,72,2032,19,864,0.079362395,1.61103988,0.953949913,2.847375965,0.177363993,DB0046510047700_,1.729551202,0.476879859,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ketorolac,DB00465
,275293,DB00996,10017412,80,38873,54,22371,0.370145273,0.852585581,0.595981813,1.22790274,0.539780216,DB0099610017412_,0.61659323,-0.159481687,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,gabapentin,DB00996
,275305,DB00275,10005750,40,2020,22,1215,0.79224159,1.093593721,0.631022306,1.941909706,0.88743507,DB0027510005750_,0.119419921,0.089469264,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,olmesartan,DB00275
,275315,DB04868,10003239,67,1574,48,1468,0.18360266,1.301720895,0.878775036,1.94080677,0.328433097,DB0486810003239_,1.113422123,0.263687154,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,nilotinib,DB04868
,275316,DB04868,10003988,30,1611,21,1495,0.396841273,1.325586844,0.730436288,2.447572684,0.566454308,DB0486810003988_,0.568358859,0.281855263,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,nilotinib,DB04868
,275339,DB00697,10007515,39,6057,26,1780,0.001711829,0.440863298,0.26085507,0.756532197,0.008556703,DB0069710007515_,4.76104038,-0.819020434,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,tizanidine,DB00697
,275361,DB00373,10028813,50,1782,21,1266,0.050509619,1.691244826,0.991638526,2.980317212,0.125940118,DB0037310028813_,2.071948739,0.525464841,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,timolol,DB00373
,275408,DB00136,10013709,55,2037,39,1643,0.599730762,1.137427749,0.73689814,1.770545651,0.744318574,DB0013610013709_,0.295286144,0.128769353,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,calcitriol,DB00136
,275462,DB00921,10022998,28,5817,34,4869,0.160009905,0.689349304,0.40205217,1.17309828,0.297475711,DB0092110022998_,1.2124227,-0.372007164,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,275503,DB06605,10009033,97,13976,91,12942,0.941727271,0.987070962,0.733031101,1.330109828,0.980911485,DB0660510009033_,0.019273053,-0.013013346,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,275504,DB06605,10017944,73,14000,41,12992,0.010929661,1.652255616,1.111166624,2.486816691,0.038223276,DB0660510017944_,3.264310635,0.502141394,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,275533,DB00281,10051398,51,11407,42,5629,0.015055365,0.599216663,0.389969122,0.925254998,0.049466282,DB0028110051398_,3.006464011,-0.512132038,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lidocaine,DB00281
,275541,DB06262,10021097,228,3572,266,4048,0.780204864,0.971363137,0.805554484,1.17055652,0.88036596,DB0626210021097_,0.127417595,-0.029054898,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,droxidopa,DB06262
,275574,DB08917,10013968,103,813,17,177,0.373069598,1.318759509,0.761091765,2.411794966,0.542779972,DB0891710013968_,0.611051248,0.276691529,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ferric carboxymaltose,DB08917
,275601,DB00480,10044016,49,67379,39,67623,0.288166447,1.260955058,0.811015095,1.97241706,0.453180271,DB0048010044016_,0.791465283,0.231869416,NA,10044016,Tooth abscess,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,275689,DB00091,10028810,67,5443,11,2659,0.000236602,2.975200432,1.557660233,6.254359876,0.001657541,DB0009110028810_,6.402420256,1.090311409,female,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,cyclosporine,DB00091
,275713,DB00490,10003988,72,3998,18,1558,0.097811095,1.558715519,0.916325047,2.786385636,0.207586971,DB0049010003988_,1.57220489,0.443862097,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,buspirone,DB00490
,275729,DB00316,10011732,60,65414,30,36923,0.660861776,1.128918512,0.716641137,1.813216358,0.793022063,DB0031610011732_,0.231904236,0.121260105,NA,10011732,Cyst,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,275830,DB01068,10050296,41,13722,11,6829,0.076181018,1.854894509,0.935622498,4.004371439,0.171763429,DB0106810050296_,1.761637161,0.617827826,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,275892,DB00273,10071134,48,8433,10,2183,0.626601207,1.24252053,0.61942335,2.759072702,0.766145493,DB0027310071134_,0.266383189,0.217142002,NA,10071134,Product physical issue,10077536,Product issues,Prod,topiramate,DB00273
,275893,DB00316,10071134,86,65388,36,36917,0.156724718,1.34872389,0.903875361,2.049948177,0.293067919,DB0031610071134_,1.22735089,0.299158879,NA,10071134,Product physical issue,10077536,Product issues,Prod,acetaminophen,DB00316
,275899,DB00996,10071134,39,38914,22,22403,1,1.020568981,0.590124789,1.807590509,1,DB0099610071134_,0,0.020360296,NA,10071134,Product physical issue,10077536,Product issues,Prod,gabapentin,DB00996
,275910,DB00987,10037844,32,2072,39,2889,0.628324307,1.144011455,0.691272225,1.880914044,0.767627441,DB0098710037844_,0.264450766,0.134540906,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,cytarabine,DB00987
,275928,DB00480,10022086,46,67382,16,67646,0.000113744,2.886400706,1.603633393,5.462846092,0.000891001,DB0048010022086_,7.023164521,1.060010296,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,275948,DB00316,10047940,30,65444,25,36928,0.160759845,0.677154239,0.384882214,1.200917363,0.298553186,DB0031610047940_,1.208807185,-0.389856205,NA,10047940,White blood cell count abnormal,10022891,Investigations,Inv,acetaminophen,DB00316
,275949,DB00480,10047940,71,67357,68,67594,0.799556402,1.047807099,0.740511923,1.483569354,0.891680255,DB0048010047940_,0.114647669,0.046699503,NA,10047940,White blood cell count abnormal,10022891,Investigations,Inv,lenalidomide,DB00480
,275970,DB00669,10022061,51,6326,6,1091,0.455560896,1.465866446,0.626936073,4.190387594,0.622986221,DB0066910022061_,0.473230878,0.382446498,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,275972,DB00316,10052015,41,65433,70,36883,1.29749847612067e-08,0.330156447,0.218869241,0.492386662,2.83969587384111e-07,DB0031610052015_,15.07439869,-1.108188656,male,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,acetaminophen,DB00316
,275973,DB00437,10052015,45,6876,85,11461,0.525623129,0.882417514,0.599937751,1.282814732,0.683571429,DB0043710052015_,0.380424124,-0.125089964,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,allopurinol,DB00437
,276004,DB09153,10046735,104,7695,49,5650,0.010586166,1.558342255,1.097285997,2.239691588,0.037244997,DB0915310046735_,3.290237643,0.443622599,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,sodium chloride,DB09153
,276079,DB01202,10076309,64,6650,44,5674,0.287240122,1.24104374,0.830936395,1.868577038,0.452088656,DB0120210076309_,0.793876976,0.215952751,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,levetiracetam,DB01202
,276090,DB00338,10027091,38,33636,20,22252,0.424855781,1.256933839,0.713012708,2.280620649,0.593612484,DB0033810027091_,0.521528556,0.228675295,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,276159,DB08815,10042458,65,1389,27,676,0.570112747,1.171538694,0.729559497,1.927896795,0.720856239,DB0881510042458_,0.327315553,0.158318008,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,lurasidone,DB08815
,276200,DB00669,10003041,186,6191,9,1088,8.1299181261995e-06,3.631547443,1.864338418,8.092363351,9.07494461514615e-05,DB0066910003041_,9.307408188,1.28965885,female,10003041,Application site erythema,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,276232,DB00973,10033775,38,3813,16,3005,0.038381264,1.871544292,1.016669181,3.602856059,0.102400683,DB0097310033775_,2.278861894,0.626763915,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,ezetimibe,DB00973
,276246,DB00502,10061920,26,1368,41,1831,0.535665904,0.848821489,0.495880635,1.429208308,0.692196956,DB0050210061920_,0.367884745,-0.163906375,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,haloperidol,DB00502
,276271,DB06643,10047626,41,52380,10,7505,0.13627653,0.587455771,0.28925358,1.315670561,0.264508281,DB0664310047626_,1.329882719,-0.531954319,NA,10047626,Vitamin D deficiency,10027433,Metabolism and nutrition disorders,Metab,denosumab,DB06643
,276281,DB06643,10040984,123,52298,13,7502,0.363377434,1.357224207,0.764456361,2.622661466,0.532896803,DB0664310040984_,0.629427489,0.30544159,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,denosumab,DB06643
,276291,DB06643,10037876,78,52343,6,7509,0.18434224,1.864930847,0.818871129,5.239058939,0.329336882,DB0664310037876_,1.110674093,0.623223973,NA,10037876,Rash papular,10040785,Skin and subcutaneous tissue disorders,Skin,denosumab,DB06643
,276332,DB00443,10033425,44,2102,14,1176,0.072151845,1.758054049,0.940805178,3.488813151,0.165036005,DB0044310033425_,1.801591616,0.564207543,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,betamethasone,DB00443
,276426,DB00363,10076309,31,4597,55,6833,0.507946462,0.837822514,0.520522639,1.326680142,0.668631173,DB0036310076309_,0.402522682,-0.176948998,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,clozapine,DB00363
,276466,DB00193,10020635,34,19286,16,8686,0.879137349,0.957056301,0.513725819,1.857901,0.949213384,DB0019310020635_,0.052121655,-0.043893059,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,tramadol,DB00193
,276523,DB00126,10064848,50,10121,34,5911,0.498054521,0.858886116,0.543891658,1.371179288,0.660096462,DB0012610064848_,0.415369301,-0.152118943,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,ascorbic acid,DB00126
,276524,DB00193,10064848,170,19150,99,8603,0.046768756,0.771407341,0.597798237,1,0.119021808,DB0019310064848_,2.128448546,-0.259538717,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,tramadol,DB00193
,276527,DB00404,10064848,89,19803,32,9830,0.122340608,1.380584019,0.911604911,2.139285105,0.244783656,DB0040410064848_,1.407380495,0.322506612,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,alprazolam,DB00404
,276582,DB00620,10030124,53,4775,33,3099,0.911862371,1.04234026,0.660774598,1.666144296,0.960554907,DB0062010030124_,0.040244134,0.041468435,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,276604,DB00620,10042674,44,4784,12,3120,0.0056962,2.391064116,1.238969281,4.981040803,0.022707913,DB0062010042674_,3.785041846,0.871738504,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,276671,DB00727,10028810,50,3793,29,4144,0.006474243,1.883524514,1.166202047,3.093852326,0.025158998,DB0072710028810_,3.682539661,0.633144763,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,nitroglycerin,DB00727
,276741,DB06413,10025482,41,1515,12,662,0.288878636,1.492718659,0.763624145,3.140907012,0.453974348,DB0641310025482_,0.789714585,0.400599061,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,armodafinil,DB06413
,276742,DB00682,10042316,38,19421,84,16280,3.47874125132338e-07,0.379225293,0.251296832,0.563012677,5.58233905928175e-06,DB0068210042316_,12.09590268,-0.969624811,NA,10042316,Subarachnoid haemorrhage,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,276745,DB09035,10016288,53,4673,82,6608,0.660648051,0.913968003,0.633126262,1.309737884,0.792837988,DB0903510016288_,0.232136381,-0.089959715,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,nivolumab,DB09035
,276815,DB05679,10037660,41,6890,31,4878,0.810933054,0.936370352,0.572144064,1.546645272,0.898264832,DB0567910037660_,0.107290341,-0.065744206,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,276832,DB00334,10029354,35,2814,36,2776,0.905229137,0.959088083,0.582908381,1.57663401,0.957772727,DB0033410029354_,0.043144766,-0.04177236,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,olanzapine,DB00334
,276905,DB01202,10046306,32,6682,20,5698,0.329377426,1.364345931,0.755786361,2.520279292,0.498011772,DB0120210046306_,0.697131564,0.310675142,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,levetiracetam,DB01202
,276910,DB09054,10012735,46,378,59,522,0.754532391,1.076594669,0.699217707,1.649648102,0.862125915,DB0905410012735_,0.148353945,0.073802975,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,idelalisib,DB09054
,276934,DB00734,10007776,40,4010,79,4823,0.012011729,0.609017971,0.404570551,0.904135141,0.04118016,DB0073410007776_,3.189798689,-0.495907503,NA,10007776,Catatonia,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,276938,DB08932,10048908,136,19307,18,6579,3.65296221440477e-05,2.574690012,1.567488711,4.478112768,0.000337379,DB0893210048908_,7.994303126,0.945729143,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,macitentan,DB08932
,276939,DB01060,10017413,44,8543,31,5050,0.473328726,0.839037564,0.517238328,1.376307985,0.639268604,DB0106010017413_,0.447430563,-0.175499801,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,amoxicillin,DB01060
,276970,DB06273,10051792,69,5026,16,1394,0.597107821,1.196071427,0.684315847,2.215312991,0.742395301,DB0627310051792_,0.297873427,0.179042375,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,tocilizumab,DB06273
,276995,DB06605,10013911,32,14041,33,13000,0.710055677,0.897807676,0.534175146,1.507279147,0.827117597,DB0660510013911_,0.189808397,-0.107799402,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,276997,DB06605,10013950,62,14011,62,12971,0.718825733,0.925793161,0.639868624,1.339383754,0.833914209,DB0660510013950_,0.181624748,-0.077104437,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,277021,DB00126,10060933,34,10137,22,5923,0.781659338,0.903009504,0.512514545,1.622308108,0.881118265,DB0012610060933_,0.126563423,-0.102022201,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,277022,DB00169,10060933,127,38564,52,18123,0.423208672,1.147742347,0.824568635,1.617860376,0.592082178,DB0016910060933_,0.52410984,0.137796836,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,277075,DB00581,10003239,48,2065,20,2049,0.000868477,2.381063693,1.380838453,4.251019584,0.004906062,DB0058110003239_,5.317283635,0.867547318,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lactulose,DB00581
,277089,DB06186,10021143,23,2186,46,3600,0.532469818,0.823473942,0.474989742,1.391184042,0.689286834,DB0618610021143_,0.372097789,-0.194223373,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipilimumab,DB06186
,277163,DB08880,10028810,47,3291,16,793,0.260560936,0.707886222,0.391715879,1.344815925,0.422018608,DB0888010028810_,0.86270587,-0.345471902,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,teriflunomide,DB08880
,277214,DB00635,10040752,43,33010,28,23766,0.719291819,1.105683672,0.671089394,1.848625697,0.834262837,DB0063510040752_,0.181206774,0.100463851,NA,10040752,Sinus tachycardia,10007541,Cardiac disorders,Card,prednisone,DB00635
,277256,DB00203,10003285,37,13841,23,8915,1,1.036163401,0.599151204,1.827748696,1,DB0020310003285_,0,0.035524854,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,277322,DB00316,10061148,79,65395,42,36911,0.777303584,1.061673117,0.721080429,1.582979323,0.878599416,DB0031610061148_,0.129426212,0.059846076,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,277378,DB00537,10017955,44,7513,45,4253,0.005605229,0.55356303,0.356241076,0.859605346,0.022421768,DB0053710017955_,3.797723015,-0.591379659,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,ciprofloxacin,DB00537
,277540,DB00203,10074300,91,13787,30,8908,0.001018347,1.95982679,1.283308896,3.070859383,0.005588153,DB0020310074300_,5.187106428,0.672856097,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,277545,DB01240,10074300,117,5634,28,1548,0.609598996,1.14808377,0.751526752,1.808805372,0.751961715,DB0124010074300_,0.285069867,0.138094265,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,epoprostenol,DB01240
,277552,DB11133,10010264,52,2379,21,1553,0.069642961,1.616261513,0.952360372,2.836757287,0.160653405,DB1113310010264_,1.828505996,0.480115774,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,277558,DB06605,10025082,45,14028,29,13004,0.131248718,1.438429336,0.881784728,2.380651309,0.257549275,DB0660510025082_,1.356544217,0.36355178,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,277680,DB00186,10013983,32,16869,21,9987,0.776331367,0.902150671,0.504103176,1.647079563,0.878049483,DB0018610013983_,0.130052328,-0.102973732,NA,10013983,Dystonia,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,277790,DB01225,10020919,34,5010,24,4616,0.357109822,1.305217916,0.750298226,2.304328933,0.526850486,DB0122510020919_,0.640838478,0.266370012,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,enoxaparin,DB01225
,277873,DB00956,10035226,34,5780,25,3442,0.42128889,0.809911486,0.468283553,1.418637209,0.590370447,DB0095610035226_,0.527005064,-0.210830314,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,hydrocodone,DB00956
,277894,DB00887,10005483,35,2306,33,1782,0.460060085,0.819644488,0.492533622,1.36667915,0.627522864,DB0088710005483_,0.465975173,-0.198884584,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,bumetanide,DB00887
,277905,DB00887,10042674,38,2303,25,1790,0.609039834,1.181368261,0.691877128,2.050031872,0.751595673,DB0088710042674_,0.285556768,0.16667331,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,277906,DB00316,10027199,38,65436,16,36937,0.395379512,1.340624859,0.729779518,2.575704638,0.565042842,DB0031610027199_,0.570853723,0.293135818,NA,10027199,Meningitis,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,277921,DB00542,10022437,36,1650,19,1405,0.10179884,1.613152636,0.896431738,2.991598106,0.213643859,DB0054210022437_,1.54344486,0.478190423,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,benazepril,DB00542
,277927,DB01268,10061309,134,2009,240,2890,0.049472673,0.803210591,0.640221736,1.004394526,0.124023769,DB0126810061309_,2.087282046,-0.219138344,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sunitinib,DB01268
,277947,DB00745,10028245,47,2530,16,1067,0.577602515,1.238768861,0.686139307,2.351498131,0.726593021,DB0074510028245_,0.319388765,0.214118033,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,modafinil,DB00745
,278123,DB06700,10047895,41,2184,9,609,0.606335666,1.270193258,0.603800336,2.989509536,0.749313947,DB0670010047895_,0.288597229,0.239169061,NA,10047895,Weight decreased,10022891,Investigations,Inv,desvenlafaxine,DB06700
,278151,DB01432,10037087,48,1243,9,661,0.002616161,2.834915777,1.3648685,6.612744639,0.012090687,DB0143210037087_,4.415319797,1.042012228,female,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,cholestyramine,DB01432
,278178,DB00836,10046735,37,5498,21,4054,0.354570607,1.299120944,0.739518734,2.339801494,0.524420408,DB0083610046735_,0.64546161,0.261687839,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,loperamide,DB00836
,278292,DB00404,10022687,42,19850,10,9852,0.038019648,2.084508927,1.028657243,4.661484355,0.101662131,DB0040410022687_,2.286100402,0.734533301,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,278295,DB00904,10022687,116,22953,40,14416,0.000914137,1.821361609,1.260612235,2.680363006,0.005118347,DB0090410022687_,5.274923767,0.599584358,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,278327,DB08904,10022052,153,11457,23,3536,0.000642376,2.052889176,1.316480393,3.341336383,0.003814059,DB0890410022052_,5.569061224,0.719248155,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,278328,DB08904,10022061,165,11445,21,3538,3.59985523274739e-05,2.428883286,1.534611776,4.035132947,0.000333118,DB0890410022061_,8.007013492,0.887431599,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,278329,DB08904,10022095,156,11454,32,3527,0.037405635,1.501078393,1.018804221,2.274677153,0.100393845,DB0890410022095_,2.298654377,0.406183779,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,278362,DB00043,10027599,58,6355,8,2292,0.00721679,2.614766812,1.240071429,6.350985138,0.027426201,DB0004310027599_,3.596256477,0.96117492,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,omalizumab,DB00043
,278422,DB00264,10037162,102,29505,29,24863,2.91958476734068e-08,2.963691177,1.944946273,4.647224354,5.91227161860938e-07,DB0026410037162_,14.34106552,1.086435511,female,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,278425,DB00635,10037162,180,32873,91,23703,0.005453388,1.426238107,1.101721164,1.857174221,0.021924488,DB0063510037162_,3.820151095,0.355040284,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,278431,DB01050,10037162,76,18032,24,9347,0.034346635,1.641434027,1.024770239,2.718498309,0.094105519,DB0105010037162_,2.363338585,0.495570267,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,ibuprofen,DB01050
,278482,DB01076,10002544,43,25704,20,25563,0.005139569,2.138165271,1.230492089,3.838009901,0.020912316,DB0107610002544_,3.867416991,0.759948111,NA,10002544,Ankle fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,278512,DB00126,10020100,50,10121,25,5920,0.551166218,1.169865349,0.709281375,1.975632841,0.705223387,DB0012610020100_,0.349240665,0.156888656,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,ascorbic acid,DB00126
,278541,DB00295,10039073,40,14623,13,9589,0.024655968,2.017625845,1.056478272,4.114193145,0.072759255,DB0029510039073_,2.62059916,0.701921496,NA,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,morphine,DB00295
,278545,DB00046,10039906,41,5418,24,4668,0.136279376,1.471794589,0.866960444,2.550649758,0.264508281,DB0004610039906_,1.329882719,0.386482465,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,insulin lispro,DB00046
,278546,DB00333,10039906,33,3038,29,3123,0.610089773,1.169738364,0.686732147,2.002496115,0.752290934,DB0033310039906_,0.28463215,0.156780103,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,methadone,DB00333
,278609,DB00230,10046306,105,19569,22,8629,0.000945243,2.104499104,1.318631812,3.503265316,0.005257457,DB0023010046306_,5.248107844,0.744077483,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,pregabalin,DB00230
,278647,DB00853,10012735,37,1784,64,2202,0.128002454,0.713641328,0.460427853,1.091996671,0.252849698,DB0085310012735_,1.374960048,-0.337374784,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,temozolomide,DB00853
,278672,DB09079,10061428,39,618,45,832,0.498404263,1.166652524,0.730067719,1.857374275,0.660264011,DB0907910061428_,0.415115508,0.154138557,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,nintedanib,DB09079
,278693,DB09027,10000060,44,5135,31,7121,0.004544649,1.968221902,1.213223851,3.228649234,0.018923739,DB0902710000060_,3.967338121,0.677130547,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,ledipasvir,DB09027
,278696,DB09027,10061428,70,5109,94,7058,0.873651799,1.028774868,0.742363745,1.420060697,0.945065179,DB0902710061428_,0.056501382,0.028368646,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ledipasvir,DB09027
,278709,DB00363,10013722,36,4592,40,6848,0.199329251,1.342103295,0.82987883,2.163519856,0.348257771,DB0036310013722_,1.054812351,0.294238007,NA,10013722,Drug level increased,10022891,Investigations,Inv,clozapine,DB00363
,278710,DB00264,10039897,37,29570,19,24873,0.082069168,1.638022994,0.917887958,3.016288691,0.181803387,DB0026410039897_,1.704829465,0.493490023,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,278712,DB00051,10005724,52,25679,9,11411,0.00528713,2.567421956,1.253142846,5.928476572,0.021388565,DB0005110005724_,3.844898845,0.942902266,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,adalimumab,DB00051
,278784,DB08931,10038428,62,6515,22,2424,0.902469937,1.048519011,0.633887485,1.795647376,0.957195726,DB0893110038428_,0.043747388,0.047378702,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,riociguat,DB08931
,278800,DB00973,10022437,83,3768,37,2984,0.003857065,1.776341407,1.188154797,2.701055139,0.016560429,DB0097310022437_,4.10073923,0.57455586,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ezetimibe,DB00973
,278854,DB01592,10020751,53,6223,12,3055,0.011758963,2.168079796,1.141778018,4.464344156,0.040519711,DB0159210020751_,3.205966744,0.773841889,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,iron,DB01592
,278998,DB00472,10074903,91,10668,47,4265,0.156575617,0.774066157,0.537530653,1.127574474,0.292830772,DB0047210074903_,1.228160406,-0.256097935,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,279019,DB00388,10007515,21,615,30,520,0.084388546,0.592140012,0.31804714,1.083836915,0.185712737,DB0038810007515_,1.683554222,-0.524012165,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,phenylephrine,DB00388
,279089,DB00273,10010144,447,8034,88,2105,0.015647534,1.330854326,1.051042484,1.700918152,0.050953347,DB0027310010144_,2.976844826,0.285821086,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,279090,DB00285,10010144,1115,9836,409,3309,0.161595011,0.917137623,0.812488441,1.036635534,0.299585616,DB0028510010144_,1.205355038,-0.086497738,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,279093,DB00660,10010144,115,1142,23,344,0.088731718,1.505851307,0.938310452,2.510314887,0.193144234,DB0066010010144_,1.644318041,0.409358391,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,metaxalone,DB00660
,279135,DB14513,10039906,47,7130,25,3539,0.802125329,0.933151757,0.561736791,1.584869735,0.892948956,DB1451310039906_,0.11322586,-0.069187436,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,magnesium,DB14513
,279216,DB06228,10029354,56,15856,73,16003,0.158520403,0.774243444,0.536233302,1.112715074,0.295521302,DB0622810029354_,1.219014357,-0.255868928,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,rivaroxaban,DB06228
,279219,DB00341,10001949,35,11370,19,5049,0.464130032,0.818043612,0.454793622,1.515368406,0.631313568,DB0034110001949_,0.459952602,-0.200839628,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,279270,DB00950,10033775,49,4669,15,2041,0.274568598,1.427955214,0.785314238,2.748182284,0.43783393,DB0095010033775_,0.825915596,0.3562435,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,fexofenadine,DB00950
,279284,DB00316,10061256,43,65431,38,36915,0.048750318,0.638389775,0.402906155,1.015186166,0.122704406,DB0031610061256_,2.097977021,-0.448806249,NA,10061256,Ischaemic stroke,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,279337,DB00557,10008190,34,5953,20,3047,0.665750035,0.870152972,0.485768217,1.598185766,0.796678137,DB0055710008190_,0.227304525,-0.139086253,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,279363,DB00557,10069339,59,5928,54,3013,0.002526309,0.55533975,0.376325841,0.821006097,0.011752927,DB0055710069339_,4.443652974,-0.588175191,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,hydroxyzine,DB00557
,279377,DB00996,10008111,40,38913,31,22394,0.21903268,0.74259051,0.452859972,1.228064384,0.372362811,DB0099610008111_,0.987886602,-0.297610517,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,279495,DB00009,10021097,57,1294,91,1460,0.051425866,0.706812958,0.494094888,1.004105549,0.127708336,DB0000910021097_,2.058006242,-0.346989205,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,alteplase,DB00009
,279619,DB00656,10040047,84,11929,59,6560,0.160602292,0.782965371,0.553763808,1.113130831,0.298344906,DB0065610040047_,1.20950506,-0.24466681,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,trazodone,DB00656
,279725,DB00316,10034701,30,65444,21,36932,0.467513961,0.806199885,0.446362705,1.481738528,0.634054201,DB0031610034701_,0.455620838,-0.215423571,NA,10034701,Peroneal nerve palsy,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,279794,DB06228,10039906,51,15861,48,16028,0.763117907,1.073650783,0.709128807,1.627923085,0.868805812,DB0622810039906_,0.14063564,0.071064788,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,279804,DB08932,10041569,48,19395,10,6587,0.175451796,1.630102733,0.813781276,3.615953197,0.317942121,DB0893210041569_,1.145885921,0.488643039,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,279847,DB00540,10003239,57,2426,25,1066,1,1.001846249,0.612043152,1.683052222,1,DB0054010003239_,0,0.001844547,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,nortriptyline,DB00540
,279872,DB00996,10006811,40,38913,13,22412,0.085896763,1.77214186,0.92827213,3.612003798,0.188195193,DB0099610006811_,1.670275595,0.572188906,NA,10006811,Bursitis,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,279950,DB00829,10039073,44,8008,7,4447,0.000646465,3.490305791,1.55791671,9.191511842,0.00383416,DB0082910039073_,5.563804782,1.249989352,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,diazepam,DB00829
,280140,DB00787,10061603,38,16962,17,17231,0.004298812,2.270700347,1.250426841,4.292040025,0.018112409,DB0078710061603_,4.011157984,0.820088307,NA,10061603,Respiratory syncytial virus infection,10021881,Infections and infestations,Infec,acyclovir,DB00787
,280145,DB08910,10061603,34,16710,22,17466,0.08279734,1.615340537,0.917344322,2.90043131,0.183069321,DB0891010061603_,1.697890393,0.479545793,NA,10061603,Respiratory syncytial virus infection,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,280147,DB00213,10062352,44,18851,12,13409,0.002496716,2.608061,1.353408058,5.426557703,0.011647206,DB0021310062352_,4.452688914,0.958607033,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,280148,DB00281,10062352,59,11399,20,5651,0.151615289,1.462418142,0.866785293,2.566922126,0.286201148,DB0028110062352_,1.251060402,0.380091327,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,lidocaine,DB00281
,280156,DB00787,10062352,35,16965,30,17218,0.535930739,1.184057936,0.705856631,1.997408399,0.692368991,DB0078710062352_,0.367636242,0.168947468,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,acyclovir,DB00787
,280220,DB08934,10028810,29,4460,30,6174,0.290662454,1.338107852,0.773757223,2.311076434,0.455946207,DB0893410028810_,0.785380445,0.291256565,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,sofosbuvir,DB08934
,280365,DB00635,10043417,91,32962,69,23725,0.748818879,0.949283455,0.686283917,1.318047912,0.857484719,DB0063510043417_,0.153751921,-0.052047837,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,280436,DB00497,10061355,33,19234,32,16343,0.619795957,0.87625052,0.522026419,1.472530526,0.760441282,DB0049710061355_,0.273856379,-0.132103247,NA,10061355,Poisoning,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,280513,DB06605,10021036,30,14043,32,13001,0.612125166,0.867942331,0.509174788,1.475816926,0.754040209,DB0660510021036_,0.282309585,-0.141630005,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,apixaban,DB06605
,280517,DB00005,10061812,52,128030,24,42395,0.184724337,0.717457271,0.434338454,1.217130779,0.329833517,DB0000510061812_,1.109167246,-0.332041886,NA,10061812,Dental operation,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,280531,DB00213,10019909,30,18865,27,13394,0.419968193,0.788893005,0.453034499,1.379834109,0.588880743,DB0021310019909_,0.52953159,-0.237124576,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,280555,DB00497,10001052,47,19220,32,16343,0.366726595,1.248887037,0.779875364,2.023476354,0.53635703,DB0049710001052_,0.62295524,0.222252784,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,280557,DB00661,10001052,41,3487,13,1582,0.302510199,1.43078444,0.749016161,2.918682063,0.468851121,DB0066110001052_,0.757470001,0.358222853,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,verapamil,DB00661
,280565,DB00472,10035669,26,10733,45,4267,1.16453017280704e-09,0.229728199,0.135875553,0.381009267,3.19016942076425e-08,DB0047210035669_,17.26060672,-1.470858413,male,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,fluoxetine,DB00472
,280570,DB00497,10040560,27,19240,35,16340,0.099068442,0.655167854,0.381216617,1.114573452,0.209457284,DB0049710040560_,1.563235457,-0.42286381,NA,10040560,Shock,10047065,Vascular disorders,Vasc,oxycodone,DB00497
,280613,DB00264,10073317,47,29560,30,24862,0.253730916,1.317666335,0.815857512,2.1584949,0.4142433,DB0026410073317_,0.881301797,0.275862244,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,280614,DB00316,10073317,130,65344,58,36895,0.148655154,1.265571743,0.921565585,1.756334731,0.282143167,DB0031610073317_,1.265340651,0.235523991,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,280618,DB00451,10073317,101,47170,17,15402,0.009827622,1.939800009,1.153045469,3.461493321,0.035078633,DB0045110073317_,3.350163082,0.662584879,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,280622,DB00813,10073317,45,10527,27,10141,0.05838686,1.605509963,0.974016558,2.69335072,0.140475847,DB0081310073317_,1.962719714,0.47344144,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,280672,DB06643,10039906,37,52384,18,7497,8.09188049470023e-05,0.294205555,0.163226034,0.549226714,0.000665712,DB0664310039906_,7.314652968,-1.223476589,male,10039906,Seizure,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,280696,DB00999,10022523,34,21396,42,12197,0.001108843,0.461480916,0.284611319,0.743445562,0.00599464,DB0099910022523_,5.1168895,-0.773314578,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,280698,DB00999,10040560,15,21415,44,12195,4.02596573037584e-09,0.194145029,0.100315472,0.355843774,9.8715027260195e-08,DB0099910040560_,16.13102865,-1.639149828,male,10040560,Shock,10047065,Vascular disorders,Vasc,hydrochlorothiazide,DB00999
,280712,DB00635,10061598,43,33010,21,23773,0.163398163,1.474634232,0.855855195,2.616702911,0.301927643,DB0063510061598_,1.197567884,0.388409981,NA,10061598,Immunodeficiency,10021428,Immune system disorders,Immun,prednisone,DB00635
,280780,DB01222,10047461,67,9207,25,5380,0.064688213,1.565980532,0.974599511,2.591280781,0.151903308,DB0122210047461_,1.884511095,0.448512166,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,budesonide,DB01222
,280801,DB00268,10048393,47,2928,8,1537,0.00145985,3.0833627,1.438759608,7.573969104,0.007520265,DB0026810048393_,4.890153844,1.126020787,female,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,ropinirole,DB00268
,280815,DB00950,10000087,70,4648,23,2033,0.257493217,1.331091368,0.818051273,2.241343034,0.418397541,DB0095010000087_,0.871323244,0.285999183,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,fexofenadine,DB00950
,280840,DB00476,10016334,61,17196,13,6164,0.087303406,1.682030912,0.913398605,3.339452946,0.190603432,DB0047610016334_,1.65756028,0.520001939,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,280849,DB14512,10033775,40,4804,13,2399,0.190815449,1.536456048,0.803151133,3.137158151,0.337579275,DB1451210033775_,1.085954908,0.429478497,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,mometasone furoate,DB14512
,281024,DB00295,10040984,47,14616,13,9589,0.005055719,2.371830046,1.261625634,4.781037198,0.020644645,DB0029510040984_,3.880299298,0.863661828,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,morphine,DB00295
,281042,DB00829,10042772,41,8011,16,4438,0.26850724,1.419557199,0.778467462,2.713182148,0.430942554,DB0082910042772_,0.841780483,0.350344992,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,281050,DB00497,10046555,27,19240,51,16324,0.00059585,0.449181638,0.270700436,0.730194411,0.003575779,DB0049710046555_,5.633572317,-0.800327935,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,oxycodone,DB00497
,281221,DB00956,10039906,37,5777,20,3447,0.784647646,1.103854996,0.623132117,2.010779716,0.883059927,DB0095610039906_,0.124362214,0.098808595,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,hydrocodone,DB00956
,281223,DB09140,10039906,35,3706,21,1777,0.473261577,0.799209923,0.450936379,1.449351367,0.639210757,DB0914010039906_,0.447521055,-0.224131635,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,oxygen,DB09140
,281326,DB00983,10076309,68,3433,54,1686,0.011147428,0.618487856,0.424175103,0.905677181,0.038819575,DB0098310076309_,3.24883064,-0.480477722,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,formoterol,DB00983
,281390,DB00316,10003041,39,65435,22,36931,1,1.000540987,0.578602109,1.771867172,1,DB0031610003041_,0,0.000540841,NA,10003041,Application site erythema,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,281432,DB00169,10018388,40,38651,17,18158,0.7782079,1.10539218,0.612417117,2.079973902,0.879072925,DB0016910018388_,0.128887421,0.100200186,NA,10018388,Glossodynia,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,281478,DB00374,10006002,83,17633,18,5706,0.131998909,1.492088897,0.887629426,2.642657143,0.258635208,DB0037410006002_,1.352336675,0.400177082,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,treprostinil,DB00374
,281517,DB00327,10039906,74,6064,38,4224,0.1471342,1.356438823,0.903448987,2.066396824,0.279953849,DB0032710039906_,1.273130516,0.304862753,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,hydromorphone,DB00327
,281530,DB09079,10016256,44,613,46,831,0.272182904,1.296452291,0.826084509,2.032400401,0.435085452,DB0907910016256_,0.832212826,0.259631527,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,nintedanib,DB09079
,281576,DB01591,10025482,52,1903,9,647,0.07178585,1.964030652,0.952115345,4.559253822,0.164391973,DB0159110025482_,1.805501626,0.674998817,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,solifenacin,DB01591
,281577,DB09401,10025482,33,727,19,741,0.065621414,1.769624287,0.966976726,3.326365656,0.153518657,DB0940110025482_,1.873933177,0.570767257,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,isosorbide,DB09401
,281582,DB00028,10006451,433,13025,77,5538,2.6989630092226e-14,2.390870449,1.868230883,3.094258138,1.49515254465259e-12,DB0002810006451_,27.22879288,0.871657504,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,281585,DB00490,10006451,42,4028,9,1567,0.116916928,1.815309102,0.868370969,4.25160367,0.236497092,DB0049010006451_,1.441819367,0.596255757,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,buspirone,DB00490
,281591,DB00424,10035664,37,1157,17,411,0.431986619,0.773269985,0.419320696,1.4813622,0.600431933,DB0042410035664_,0.510105994,-0.257127022,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,hyoscyamine,DB00424
,281597,DB00916,10040753,45,5278,14,2417,0.259371981,1.471886347,0.791551298,2.909355065,0.42048292,DB0091610040753_,0.866351418,0.386544807,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,metronidazole,DB00916
,281638,DB00404,10036018,46,19846,12,9850,0.049892948,1.902529598,0.991262873,3.947702578,0.12481547,DB0040410036018_,2.080918871,0.643184368,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,alprazolam,DB00404
,281651,DB09027,10037660,49,5130,55,7097,0.318590765,1.232481831,0.819752126,1.848446759,0.486600904,DB0902710037660_,0.720310992,0.209029885,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,281714,DB00169,10018304,60,38631,14,18161,0.017173061,2.014755212,1.112376326,3.90544902,0.054824061,DB0016910018304_,2.903626116,0.700497705,NA,10018304,Glaucoma,10015919,Eye disorders,Eye,cholecalciferol,DB00169
,281746,DB00480,10023644,123,67305,104,67558,0.207169616,1.187135102,0.90667429,1.556793024,0.357839551,DB0048010023644_,1.027670574,0.171542927,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,lenalidomide,DB00480
,281755,DB00484,10033371,45,2462,22,1758,0.169387652,1.46043871,0.855252428,2.563673729,0.310093976,DB0048410033371_,1.170879878,0.378736877,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,brimonidine,DB00484
,281779,DB00198,10013968,71,1204,25,978,0.000310089,2.306063772,1.430833703,3.828831626,0.002073701,DB0019810013968_,6.178420378,0.835542076,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oseltamivir,DB00198
,281806,DB00121,10035528,38,4185,15,453,0.000134343,0.274344573,0.146069591,0.541237133,0.001025324,DB0012110035528_,6.882746821,-1.293370398,male,10035528,Platelet count decreased,10022891,Investigations,Inv,biotin,DB00121
,281821,DB01234,10021519,32,31593,37,32851,0.718340009,0.899310917,0.542186416,1.484134184,0.833618427,DB0123410021519_,0.181979503,-0.106126457,NA,10021519,Impaired healing,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,281888,DB00368,10006093,32,628,22,776,0.037319207,1.796582382,1.000559574,3.280724795,0.100218162,DB0036810006093_,2.300405851,0.585886183,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,norepinephrine,DB00368
,281907,DB01104,10017413,61,15402,25,7261,0.643490204,1.15027955,0.710704653,1.914077889,0.779830794,DB0110410017413_,0.248678314,0.140005,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,sertraline,DB01104
,281909,DB14500,10017413,73,7736,40,4033,0.842230708,0.951429604,0.637133354,1.439028186,0.919665828,DB1450010017413_,0.083744906,-0.049789579,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,potassium,DB14500
,281950,DB14500,10020642,51,7758,19,4054,0.25541803,1.402616222,0.812659776,2.519057228,0.416131832,DB1450010020642_,0.876753164,0.338339223,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,potassium,DB14500
,281996,DB00350,10001760,52,488,12,449,3.56469503183557e-06,3.981880183,2.064557913,8.305558839,4.39587187012892e-05,DB0035010001760_,10.03225958,1.381754115,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,minoxidil,DB00350
,282162,DB00814,10007882,38,8249,20,3395,0.386018002,0.781968714,0.442999793,1.420657412,0.556154527,DB0081410007882_,0.586709097,-0.245940547,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,meloxicam,DB00814
,282259,DB00476,10011781,66,17191,10,6167,0.008532167,2.367417165,1.208856184,5.168785346,0.031361768,DB0047610011781_,3.462165702,0.861799557,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,duloxetine,DB00476
,282485,DB00642,10016256,47,487,48,485,0.91486347,0.975163185,0.625036926,1.520690369,0.961903265,DB0064210016256_,0.03884139,-0.025150452,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pemetrexed,DB00642
,282486,DB00966,10016256,62,651,16,418,0.000987707,2.486339125,1.394394703,4.680545192,0.005449027,DB0096610016256_,5.212318269,0.910811398,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,telmisartan,DB00966
,282680,DB00112,10020937,91,5842,38,4053,0.008733916,1.661311888,1.123351009,2.499666083,0.031955872,DB0011210020937_,3.443399317,0.507607584,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,bevacizumab,DB00112
,282685,DB00958,10020937,56,4538,20,2565,0.092003905,1.582541043,0.932450998,2.790943802,0.198434615,DB0095810020937_,1.617295629,0.45903181,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,carboplatin,DB00958
,282690,DB00338,10021639,40,33634,15,22257,0.072251335,1.764622514,0.95346847,3.439836198,0.165213252,DB0033810021639_,1.800518203,0.567936794,NA,10021639,Incontinence,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,282976,DB00341,10029148,42,11363,14,5054,0.387330459,1.334258707,0.713554807,2.64788237,0.557406195,DB0034110029148_,0.584461051,0.288375862,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,cetirizine,DB00341
,282980,DB00476,10029148,64,17193,19,6158,0.533792295,1.206447935,0.712945744,2.134382202,0.690403763,DB0047610029148_,0.370478688,0.187680452,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,duloxetine,DB00476
,283025,DB00814,10031161,74,8213,8,3407,4.07194095872079e-05,3.837167437,1.846496479,9.225862038,0.000370413,DB0081410031161_,7.900890728,1.344734448,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,283054,DB00331,10031252,31,24915,58,20694,0.00024637,0.443937839,0.277305975,0.698436561,0.001714093,DB0033110031252_,6.36887116,-0.812070728,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,metformin,DB00331
,283258,DB00112,10038063,48,5885,27,4064,0.412004275,1.227645537,0.749374279,2.049886363,0.581427814,DB0011210038063_,0.542268453,0.205098137,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,283324,DB00338,10040026,34,33640,16,22256,0.31209494,1.405877103,0.75489536,2.728318578,0.479617092,DB0033810040026_,0.734767219,0.340661381,NA,10040026,Sensory disturbance,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,283396,DB01067,10040753,43,4318,14,4809,2.38646998451944e-05,3.420287677,1.832305328,6.77920256,0.000232069,DB0106710040753_,8.368477145,1.229724664,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,glipizide,DB01067
,283456,DB01067,10042674,35,4326,29,4794,0.260270445,1.337412892,0.792667208,2.272342969,0.421646142,DB0106710042674_,0.863588843,0.29073707,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,glipizide,DB01067
,283563,DB00338,10044055,49,33625,13,22259,0.002532476,2.495096789,1.332565688,5.014623102,0.011778488,DB0033810044055_,4.441480467,0.914327522,NA,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,283614,DB00338,10048762,34,33640,18,22254,0.481418718,1.249544887,0.685980786,2.350575338,0.646045387,DB0033810048762_,0.436885519,0.222779395,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,283632,DB00331,10048908,46,24900,26,20726,0.124045257,1.472638347,0.891063024,2.482564966,0.247150244,DB0033110048908_,1.397758854,0.387055586,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,metformin,DB00331
,283634,DB00341,10048908,57,11348,24,5044,0.904185116,1.055644708,0.643873298,1.780918615,0.957497529,DB0034110048908_,0.043432138,0.054151678,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,cetirizine,DB00341
,283644,DB01076,10048908,58,25689,43,25540,0.163082104,1.34100163,0.888078633,2.038917579,0.301502593,DB0107610048908_,1.198976664,0.29341682,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,atorvastatin,DB01076
,284023,DB00331,10061218,42,24904,22,20730,0.079606292,1.58910085,0.926984445,2.796123463,0.177755715,DB0033110061218_,1.727345061,0.463168353,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,284097,DB00814,10061818,37,8250,15,3400,1,1.016571043,0.543759108,1.996488051,1,DB0081410061818_,0,0.016435242,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,284119,DB00341,10062244,62,11343,18,5050,0.115438454,1.533463281,0.89430214,2.757482567,0.234326956,DB0034110062244_,1.45103789,0.42752876,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,284362,DB00295,10003445,32,14631,19,9583,0.776218189,1.103137996,0.606136149,2.061179698,0.877982174,DB0029510003445_,0.130128988,0.098158842,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,284378,DB00390,10003988,72,4073,35,3266,0.018247327,1.649442904,1.083647282,2.552873608,0.057464923,DB0039010003988_,2.856580554,0.500437597,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,digoxin,DB00390
,284493,DB00341,10013971,54,11351,20,5048,0.530007416,1.200712683,0.706212581,2.12010671,0.687165262,DB0034110013971_,0.375180459,0.182915283,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cetirizine,DB00341
,284498,DB01373,10013971,83,22637,11,7370,0.002550206,2.456660632,1.303438591,5.112949427,0.01184209,DB0137310013971_,4.436095124,0.898802961,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,284500,DB13867,10013971,46,4504,10,2544,0.004700423,2.597921339,1.29038699,5.783712394,0.019461388,DB1386710013971_,3.939322869,0.95471164,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,284595,DB00927,10030095,49,7448,24,4992,0.231856052,1.368387199,0.822386016,2.335107072,0.388124845,DB0092710030095_,0.946428226,0.313632819,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,284598,DB00012,10030124,45,1601,27,1286,0.279831648,1.338615498,0.807723728,2.256925362,0.443678105,DB0001210030124_,0.812655968,0.29163587,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,darbepoetin alfa,DB00012
,284656,DB00341,10038435,69,11336,35,5033,0.52353709,0.875298289,0.573841279,1.356753137,0.681717293,DB0034110038435_,0.383140234,-0.133190549,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,cetirizine,DB00341
,284743,DB00695,10059168,74,27975,16,20512,9.77339860794243e-07,3.391052941,1.955920965,6.241226806,1.40187602952124e-05,DB0069510059168_,11.1751141,1.221140475,female,10059168,Oxygen consumption increased,10022891,Investigations,Inv,furosemide,DB00695
,284829,DB00653,10021097,49,1043,39,783,0.825846471,0.943257232,0.600069766,1.491252493,0.908031369,DB0065310021097_,0.096476354,-0.058416253,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,magnesium sulfate,DB00653
,284900,DB11988,10007882,35,3109,24,1202,0.039917746,0.563918277,0.324448164,0.995393635,0.10552529,DB1198810007882_,2.248804641,-0.572845937,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,ocrelizumab,DB11988
,285011,DB00465,10000081,44,2060,15,868,0.565224414,1.235882923,0.670393712,2.404186829,0.716865154,DB0046510000081_,0.332867525,0.211785632,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ketorolac,DB00465
,285028,DB00007,10048959,23,1924,64,4388,0.481852389,0.819651096,0.484099784,1.343162515,0.646313885,DB0000710048959_,0.436470004,-0.198876522,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,leuprolide,DB00007
,285095,DB00381,10062070,29,29331,43,22844,0.008483977,0.525275772,0.316158434,0.861224419,0.031219564,DB0038110062070_,3.466710321,-0.643831874,NA,10062070,Peritonitis bacterial,10021881,Infections and infestations,Infec,amlodipine,DB00381
,285103,DB00203,10061603,30,13848,30,8908,0.111181591,0.643302889,0.374365916,1.105316141,0.227859196,DB0020310061603_,1.479027404,-0.44113961,NA,10061603,Respiratory syncytial virus infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,285108,DB00635,10014184,39,33014,21,23773,0.297985035,1.337299484,0.767378619,2.393392205,0.463889168,DB0063510014184_,0.768109618,0.29065227,NA,10014184,Eczema,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,285142,DB08868,10005425,59,9143,16,2495,1,1.00626832,0.570223865,1.876962442,1,DB0886810005425_,0,0.006248756,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,fingolimod,DB08868
,285315,DB00230,10048010,650,19024,213,8438,0.000126452,1.353569155,1.155126495,1.591000755,0.00097515,DB0023010048010_,6.93291894,0.302744923,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,285358,DB13961,10000060,83,9374,33,6381,0.007833095,1.712037241,1.129453105,2.649837915,0.029278986,DB1396110000060_,3.530885205,0.53768403,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,fish oil,DB13961
,285453,DB00451,10051118,123,47148,27,15392,0.070680844,1.487170955,0.97384222,2.348088978,0.162505662,DB0045110051118_,1.817042435,0.396875627,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,285489,DB00804,10069339,61,2939,23,876,0.359144575,0.790559082,0.478957418,1.346684189,0.528932072,DB0080410069339_,0.636895264,-0.235014886,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,dicyclomine,DB00804
,285490,DB00868,10069339,31,2953,35,1611,0.004053572,0.48326924,0.286976942,0.810260303,0.01727294,DB0086810069339_,4.058614147,-0.727181349,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,benzonatate,DB00868
,285491,DB01129,10069339,39,873,37,399,0.002347342,0.482024031,0.29448223,0.790221219,0.011081158,DB0112910069339_,4.502509105,-0.729761309,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,rabeprazole,DB01129
,285493,DB00804,10070863,42,2958,20,879,0.09392151,0.624121367,0.356169429,1.128391585,0.201619248,DB0080410070863_,1.601374272,-0.471410431,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,dicyclomine,DB00804
,285494,DB00820,10070863,17,11898,35,5781,3.86559093609711e-07,0.236021081,0.123871042,0.433183843,6.13013923108974e-06,DB0082010070863_,12.0022931,-1.443834153,male,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,tadalafil,DB00820
,285496,DB01069,10070863,265,6435,80,2315,0.190679091,1.191646171,0.920256354,1.557099968,0.337417525,DB0106910070863_,1.086434169,0.175335688,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,promethazine,DB01069
,285583,DB00399,10013952,48,6944,27,4971,0.348503476,1.272631774,0.777068856,2.124361224,0.518039476,DB0039910013952_,0.657703832,0.241087019,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zoledronic acid,DB00399
,285695,DB01373,10019022,41,22679,11,7370,0.632248001,1.211240439,0.611019715,2.614356592,0.770933997,DB0137310019022_,0.260152516,0.191644991,NA,10019022,Haemorrhoids,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,285708,DB01065,10028735,42,4289,8,3043,0.000146664,3.724251776,1.724128058,9.1971186,0.001105238,DB0106510028735_,6.80769433,1.314865966,female,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,melatonin,DB01065
,285946,DB04854,10018627,38,743,111,1375,0.020096707,0.6336599,0.421700578,0.934630187,0.061989314,DB0485410018627_,2.780793258,-0.456242903,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,febuxostat,DB04854
,286022,DB01275,10020919,47,3932,32,3317,0.366026698,1.238987373,0.772031097,2.011501108,0.535601612,DB0127510020919_,0.624364655,0.214294412,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,hydralazine,DB01275
,286032,DB00836,10005750,43,5492,50,4025,0.027079968,0.630324287,0.40847566,0.96905863,0.07820226,DB0083610005750_,2.54845673,-0.461520851,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,loperamide,DB00836
,286290,DB00193,10036018,54,19266,25,8677,0.903469357,0.972818656,0.594578509,1.632572172,0.957394507,DB0019310036018_,0.043539739,-0.027557591,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,tramadol,DB00193
,286332,DB00016,10025482,90,2672,61,2229,0.245260857,1.230745454,0.874797832,1.741439633,0.404060248,DB0001610025482_,0.906191283,0.207620046,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,286374,DB08907,10069339,72,4181,112,3798,0.0004255,0.584012274,0.426703839,0.79501657,0.002697929,DB0890710069339_,5.915270779,-0.537833278,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,canagliflozin,DB08907
,286434,DB00451,10062244,132,47139,27,15392,0.026545412,1.596278249,1.048571571,2.514079431,0.076956226,DB0045110062244_,2.564518516,0.467674825,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levothyroxine,DB00451
,286555,DB00035,10013709,47,623,50,492,0.167347158,0.742535517,0.478850215,1.149702006,0.307334152,DB0003510013709_,1.179819679,-0.297684574,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,desmopressin,DB00035
,286574,DB00182,10047571,40,5154,10,2842,0.025184354,2.205476062,1.081795523,4.953727761,0.073905409,DB0018210047571_,2.604969257,0.790943387,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,amphetamine,DB00182
,286577,DB00722,10051076,44,25359,41,25991,0.666017453,1.099905655,0.701984224,1.726688963,0.796884442,DB0072210051076_,0.227045601,0.095224408,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,286741,DB01390,10033371,42,1367,28,1489,0.052316736,1.633582626,0.982872179,2.753034209,0.129376744,DB0139010033371_,2.045026636,0.490775533,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sodium bicarbonate,DB01390
,286811,DB01136,10062070,23,9861,34,11081,0.353076996,0.760174529,0.427258144,1.329733949,0.522808147,DB0113610062070_,0.648540713,-0.274207228,NA,10062070,Peritonitis bacterial,10021881,Infections and infestations,Infec,carvedilol,DB01136
,286815,DB00153,10064848,78,7345,37,3402,0.919840094,0.976399649,0.650701418,1.488960533,0.964515682,DB0015310064848_,0.036129187,-0.023883299,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,ergocalciferol,DB00153
,286816,DB00186,10064848,65,16836,40,9968,0.840340905,0.96213516,0.638560613,1.465551104,0.918366576,DB0018610064848_,0.085158648,-0.038600339,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,lorazepam,DB00186
,286820,DB00575,10064848,60,5184,38,3791,0.537827653,1.154622226,0.754730535,1.786026617,0.693930885,DB0057510064848_,0.365382913,0.143773213,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,clonidine,DB00575
,286822,DB00697,10064848,41,6055,11,1795,0.869324669,1.104932911,0.556349572,2.388707899,0.941838249,DB0069710064848_,0.059921729,0.099784619,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,tizanidine,DB00697
,286823,DB00758,10064848,77,8223,88,9986,0.69540621,1.062568698,0.771149847,1.461620799,0.81661725,DB0075810064848_,0.202584776,0.060689277,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,clopidogrel,DB00758
,286827,DB01275,10064848,54,3925,71,3278,0.014215506,0.635239115,0.436050739,0.920864439,0.047154792,DB0127510064848_,3.054319649,-0.453753792,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,hydralazine,DB01275
,286828,DB01390,10064848,33,1376,21,1496,0.073010736,1.708146571,0.953989268,3.123058438,0.166551287,DB0139010064848_,1.79245199,0.535408906,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,sodium bicarbonate,DB01390
,286870,DB00230,10041569,34,19640,16,8635,0.877971329,0.934289767,0.501517323,1.813698232,0.948285522,DB0023010041569_,0.053099639,-0.067968645,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,286913,DB08932,10052270,169,19274,26,6571,4.66050380857278e-05,2.216077042,1.459021721,3.493742438,0.000416081,DB0893210052270_,7.784631161,0.795738534,NA,10052270,Catheter site pruritus,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,286923,DB00722,10060820,51,25352,20,26012,0.000184632,2.616431784,1.532122775,4.633941984,0.001348255,DB0072210060820_,6.608944446,0.961811475,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,286929,DB08895,10060820,73,28041,12,6634,0.271269846,1.439187522,0.775498481,2.914052087,0.434027292,DB0889510060820_,0.834647863,0.364078733,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,287167,DB00722,10017888,38,25365,21,26011,0.026042953,1.855574707,1.061383556,3.329017858,0.075815597,DB0072210017888_,2.579451242,0.618194463,NA,10017888,Gastroenteritis,10021881,Infections and infestations,Infec,lisinopril,DB00722
,287414,DB01225,10028810,43,5001,18,4622,0.004362419,2.207577222,1.244656962,4.07313752,0.018318747,DB0122510028810_,3.999830321,0.791895634,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,enoxaparin,DB01225
,287716,DB00181,10054112,73,9783,42,5829,0.9230189,1.035608271,0.697982582,1.554108361,0.966306952,DB0018110054112_,0.03427374,0.034988955,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,baclofen,DB00181
,287717,DB00207,10054112,156,8924,126,5329,0.012996694,0.739367616,0.579412039,0.944982835,0.04387031,DB0020710054112_,3.126517501,-0.301960031,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,azithromycin,DB00207
,287718,DB00575,10054112,70,5174,46,3783,0.636440867,1.112648348,0.75423428,1.655053347,0.773999962,DB0057510054112_,0.256183454,0.106743073,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,clonidine,DB00575
,287721,DB00646,10054112,54,3399,29,1971,0.818744852,1.079763958,0.67287033,1.765017397,0.903295656,DB0064610054112_,0.101705364,0.07674246,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,nystatin,DB00646
,287723,DB00741,10054112,34,4060,20,3154,0.338993865,1.320589642,0.737024886,2.426215163,0.508057234,DB0074110054112_,0.677161171,0.278078335,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,hydrocortisone,DB00741
,287724,DB00761,10054112,196,15111,81,8544,0.01969329,1.368149699,1.049335422,1.797590616,0.061064472,DB0076110054112_,2.795825058,0.313459243,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,potassium chloride,DB00761
,287727,DB01068,10054112,108,13655,63,6777,0.327919652,0.850819933,0.616985388,1.181747946,0.49644903,DB0106810054112_,0.70027446,-0.161554767,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,clonazepam,DB01068
,287731,DB01307,10054112,37,2487,31,2038,1,0.978065523,0.588113388,1.636551003,1,DB0130710054112_,0,-0.022178614,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,insulin detemir,DB01307
,288024,DB00158,10022000,220,16595,80,8024,0.029948407,1.329701001,1.023453939,1.742181271,0.084599537,DB0015810022000_,2.469826489,0.284954105,NA,10022000,Influenza,10021881,Infections and infestations,Infec,folic acid,DB00158
,288034,DB00758,10037423,54,8246,50,10024,0.168057414,1.312840776,0.87591033,1.971103781,0.308240117,DB0075810037423_,1.176876198,0.272193321,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,288038,DB00046,10061818,27,5432,35,4657,0.124845793,0.661400338,0.384396748,1.126536697,0.248359317,DB0004610061818_,1.392878722,-0.413395968,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,insulin lispro,DB00046
,288098,DB01175,10069339,89,10635,99,4793,1.5248332587575e-09,0.405182086,0.300186085,0.546199648,4.07733898336124e-08,DB0117510069339_,17.01523618,-0.903418717,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,escitalopram,DB01175
,288112,DB01076,10048439,49,25698,9,25574,8.89396643454622e-08,5.417868724,2.632881807,12.54789654,1.62571563096e-06,DB0107610048439_,13.32956245,1.689702514,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,288129,DB00761,10006093,43,15264,50,8575,0.000493366,0.483135722,0.313502956,0.741862946,0.003058883,DB0076110006093_,5.789705304,-0.727457667,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,288179,DB00390,10043071,39,4106,18,3283,0.060474289,1.732258266,0.965523184,3.223535784,0.144256892,DB0039010043071_,1.936159595,0.549425913,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,digoxin,DB00390
,288205,DB00927,10047302,19,7478,35,4981,0.000255803,0.361619147,0.195144872,0.650604921,0.001769883,DB0092710047302_,6.336841621,-1.0171637,male,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,famotidine,DB00927
,288404,DB11089,10027599,47,10128,11,8396,4.97569069215884e-05,3.541739057,1.809129192,7.576551073,0.000439765,DB1108910027599_,7.729270685,1.264617866,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,docusate,DB11089
,288493,DB01050,10060800,88,18020,29,9342,0.039600662,1.573124409,1.022709756,2.485301224,0.104856445,DB0105010060800_,2.255163057,0.453063711,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,ibuprofen,DB01050
,288538,DB00273,10028810,89,8392,21,2172,0.81251537,1.09688546,0.67401562,1.863024876,0.899183904,DB0027310028810_,0.1062677,0.092474764,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,topiramate,DB00273
,288540,DB00285,10028810,102,10849,17,3701,0.004152451,2.046843576,1.215595089,3.654750051,0.017605804,DB0028510028810_,4.039526669,0.716298888,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,venlafaxine,DB00285
,288551,DB01069,10028810,69,6631,14,2381,0.05938136,1.769680469,0.984493349,3.411284391,0.142340891,DB0106910028810_,1.949530454,0.570799004,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,promethazine,DB01069
,288565,DB00310,10003549,33,911,38,743,0.180335071,0.708423631,0.425974735,1.172803685,0.324265108,DB0031010003549_,1.126193863,-0.344713015,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,chlorthalidone,DB00310
,288599,DB01104,10046306,90,15373,30,7256,0.116056289,1.415987604,0.926441272,2.220151739,0.235245002,DB0110410046306_,1.447127748,0.347827241,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,sertraline,DB01104
,288600,DB01109,10046306,64,4348,26,4244,0.000112899,2.402588661,1.497852044,3.95761523,0.000885437,DB0110910046306_,7.029428915,0.876546765,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,heparin,DB01109
,288627,DB06273,10003988,58,5037,9,1401,0.1343663,1.792288539,0.879143244,4.125416689,0.261780988,DB0627310003988_,1.34024705,0.583493317,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tocilizumab,DB06273
,288644,DB00177,10040753,56,4744,17,2833,0.014467777,1.967006965,1.123693878,3.618733779,0.047864761,DB0017710040753_,3.039375726,0.676513081,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,valsartan,DB00177
,288645,DB01211,10040753,64,1588,24,763,0.353331486,1.28119631,0.783037135,2.159709152,0.523114599,DB0121110040753_,0.64795472,0.247794259,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,clarithromycin,DB01211
,288693,DB01109,10006451,44,4368,18,4252,0.001364998,2.379467338,1.344397494,4.382324937,0.007116017,DB0110910006451_,4.945407064,0.866876655,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,heparin,DB01109
,288710,DB00502,10007776,31,1363,45,1827,0.814725836,0.923408637,0.56170017,1.500628839,0.900595148,DB0050210007776_,0.104699459,-0.079683415,NA,10007776,Catatonia,10037175,Psychiatric disorders,Psych,haloperidol,DB00502
,288789,DB00497,10044034,52,19215,41,16334,0.755330555,1.078154731,0.701811486,1.666109211,0.862723837,DB0049710044034_,0.147660643,0.075250998,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,oxycodone,DB00497
,288823,DB00188,10028810,117,7769,89,8739,0.006067271,1.478694897,1.110831185,1.974041206,0.02387756,DB0018810028810_,3.734816179,0.391159872,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,bortezomib,DB00188
,288860,DB00319,10048302,19,1373,73,1780,8.43139113807841e-06,0.337537405,0.191370445,0.568577785,9.35726333784777e-05,DB0031910048302_,9.276772596,-1.086078947,male,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,piperacillin,DB00319
,288880,DB01234,10067482,38,31587,53,32835,0.173707999,0.745314544,0.477923102,1.152385557,0.315783578,DB0123410067482_,1.15269818,-0.293948944,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,288888,DB00669,10008479,73,6304,12,1085,1,1.047021426,0.562210635,2.126027357,1,DB0066910008479_,0,0.045949396,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,289009,DB00512,10010774,37,4700,23,5075,0.038340394,1.736937581,1.003441125,3.066899228,0.102325055,DB0051210010774_,2.279600714,0.552123552,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,vancomycin,DB00512
,289013,DB01012,10010774,98,10534,81,8604,0.939987561,0.988206383,0.727623219,1.345143678,0.979390468,DB0101210010774_,0.020824872,-0.011863714,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,cinacalcet,DB01012
,289017,DB00136,10011224,32,2060,22,1660,0.584931621,1.172060137,0.657369027,2.125894505,0.732568728,DB0013610011224_,0.311198116,0.158763001,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcitriol,DB00136
,289082,DB00584,10022437,43,2038,18,1856,0.006198091,2.175059357,1.223281156,4.0222099,0.024288755,DB0058410022437_,3.717741795,0.777055955,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,enalapril,DB00584
,289084,DB00646,10022437,63,3390,28,1972,0.272966538,1.308787345,0.822924485,2.129700622,0.435947032,DB0064610022437_,0.830234528,0.269101018,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,nystatin,DB00646
,289131,DB09153,10047924,33,7766,25,5674,0.894784429,0.964403065,0.555571201,1.693719721,0.955976233,DB0915310047924_,0.045022227,-0.036245954,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,289150,DB00584,10061428,42,2039,42,1832,0.659514618,0.898504571,0.568820213,1.419297344,0.792035804,DB0058410061428_,0.233148681,-0.107023485,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,enalapril,DB00584
,289157,DB00136,10062070,23,2069,38,1644,0.006057109,0.481022468,0.272422999,0.83217075,0.023843844,DB0013610062070_,3.736229189,-0.731841299,NA,10062070,Peritonitis bacterial,10021881,Infections and infestations,Infec,calcitriol,DB00136
,289243,DB00043,10050584,47,6366,12,2288,0.373463793,1.407600353,0.733586054,2.920599105,0.543233215,DB0004310050584_,0.610216558,0.341886377,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,omalizumab,DB00043
,289246,DB00182,10022095,46,5148,9,2843,0.00264767,2.822323239,1.362388569,6.56756227,0.012207333,DB0018210022095_,4.40571841,1.037560389,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,289313,DB00338,10028164,49,33625,15,22257,0.007062896,2.162229821,1.19217854,4.152663303,0.02697395,DB0033810028164_,3.612883699,0.771140014,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,omeprazole,DB00338
,289317,DB01234,10028164,111,31514,51,32837,5.59215627998423e-07,2.267823399,1.613111391,3.225910808,8.57583592878562e-06,DB0123410028164_,11.66656209,0.818820516,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,dexamethasone,DB01234
,289319,DB08910,10028164,53,16691,21,17467,9.67798173320458e-05,2.64112117,1.56549063,4.611463496,0.000774386,DB0891010028164_,7.163440302,0.971203513,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,pomalidomide,DB08910
,289355,DB11133,10000087,41,2390,23,1551,0.608437055,1.156830161,0.674968714,2.028026529,0.751036372,DB1113310000087_,0.286301198,0.145683645,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,omega-3 fatty acids,DB11133
,289406,DB00177,10015090,38,4762,16,2834,0.262054687,1.413368202,0.767832635,2.720314478,0.423779221,DB0017710015090_,0.858542664,0.345975652,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,valsartan,DB00177
,289416,DB00177,10022000,42,4758,13,2837,0.03619413,1.926223882,1.012200665,3.918273757,0.097927197,DB0017710022000_,2.323530965,0.655561549,NA,10022000,Influenza,10021881,Infections and infestations,Infec,valsartan,DB00177
,289418,DB00956,10022000,44,5770,21,3446,0.441776469,1.251326549,0.726881206,2.219566855,0.609894929,DB0095610022000_,0.494468584,0.224204228,NA,10022000,Influenza,10021881,Infections and infestations,Infec,hydrocodone,DB00956
,289494,DB01098,10060800,36,8113,14,7195,0.006947688,2.280268485,1.199104862,4.580509283,0.026644292,DB0109810060800_,3.625180331,0.824293193,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,rosuvastatin,DB01098
,289650,DB00003,10058080,33,2965,25,2568,0.691884357,1.14322982,0.657480526,2.011126785,0.814245817,DB0000310058080_,0.205492973,0.133857432,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,dornase alfa,DB00003
,289653,DB00684,10058080,31,2761,25,2323,0.893678178,1.043288638,0.59425899,1.848669635,0.955733567,DB0068410058080_,0.0452761,0.042377876,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,tobramycin,DB00684
,289654,DB01222,10058080,52,9222,32,5373,0.821050567,0.946775268,0.59725045,1.521921171,0.904700649,DB0122210058080_,0.100151165,-0.054693524,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,budesonide,DB01222
,289675,DB00005,10051118,30,128052,20,42399,0.020587665,0.496642842,0.272845395,0.922844457,0.063232854,DB0000510051118_,2.760931264,-0.69988414,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,289705,DB00080,10034133,16,624,41,872,0.040525839,0.545542412,0.283095979,1.004129883,0.10669822,DB0008010034133_,2.237750805,-0.605974727,NA,10034133,Pathogen resistance,10021881,Infections and infestations,Infec,daptomycin,DB00080
,289707,DB00254,10037377,30,5905,28,3360,0.074035942,0.609656401,0.351326626,1.061070267,0.168270133,DB0025410037377_,1.782184654,-0.494859758,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxycycline,DB00254
,289791,DB00318,10013709,73,4210,34,1805,0.671969712,0.920547818,0.602330655,1.432150812,0.800901423,DB0031810013709_,0.222017406,-0.082786331,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,codeine,DB00318
,289797,DB01069,10022004,50,6650,9,2386,0.0541204,1.993259177,0.968508006,4.617579594,0.132709665,DB0106910022004_,2.019591508,0.689771077,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,promethazine,DB01069
,289913,DB00410,10000081,34,1571,18,991,0.6663531,1.191413755,0.650147346,2.253876401,0.797118793,DB0041010000081_,0.226751562,0.175140631,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,mupirocin,DB00410
,289931,DB00813,10001052,18,10554,42,10126,0.001132403,0.411196752,0.222651977,0.730567881,0.006101303,DB0081310001052_,5.099252855,-0.888683464,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fentanyl,DB00813
,290133,DB09035,10069339,98,4628,217,6473,0.000156141,0.631678139,0.490946299,0.808058668,0.001167781,DB0903510069339_,6.752650265,-0.459375288,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,nivolumab,DB09035
,290205,DB00203,10054112,556,13322,229,8709,2.95513682328571e-09,1.587191182,1.354968083,1.863900179,7.47601264678199e-08,DB0020310054112_,16.40898116,0.461965902,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,290206,DB00374,10054112,475,17241,135,5589,0.197231489,1.14058667,0.937842705,1.39470171,0.34568445,DB0037410054112_,1.062228913,0.131542753,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,treprostinil,DB00374
,290209,DB06403,10054112,360,21111,101,6560,0.40726965,1.107577938,0.884268002,1.397634756,0.576813554,DB0640310054112_,0.550236194,0.102175593,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,ambrisentan,DB06403
,290233,DB00051,10038695,37,25694,23,11397,0.208925019,0.713560761,0.412729363,1.258470934,0.359992861,DB0005110038695_,1.021671078,-0.337487686,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,290249,DB01026,10013709,57,1053,60,1008,0.635564608,0.909441732,0.614900433,1.343776067,0.77352116,DB0102610013709_,0.256802253,-0.094924349,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ketoconazole,DB01026
,290326,DB00316,10049054,44,65430,16,36937,0.140451237,1.552442445,0.858702322,2.947835963,0.270468571,DB0031610049054_,1.307599374,0.439829462,NA,10049054,Brain death,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,290409,DB01590,10013952,17,4721,44,2823,6.55319993467266e-08,0.231079418,0.123513006,0.413621061,1.23478276463872e-06,DB0159010013952_,13.6046155,-1.464993828,male,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,everolimus,DB01590
,290473,DB00264,10050528,39,29568,45,24847,0.154996299,0.728299643,0.461736923,1.1442248,0.29078746,DB0026410050528_,1.235162655,-0.317042719,NA,10050528,Ejection fraction decreased,10022891,Investigations,Inv,metoprolol,DB00264
,290560,DB00455,10042682,58,9343,20,5098,0.075887671,1.58233585,0.936367684,2.780853277,0.17130775,DB0045510042682_,1.764293633,0.458902142,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,290583,DB00927,10061481,36,7461,22,4994,0.78938815,1.095306107,0.626266175,1.956936325,0.885855574,DB0092710061481_,0.12120135,0.091033874,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,famotidine,DB00927
,290680,DB06605,10024855,95,13978,95,12938,0.610598442,0.925617574,0.68834772,1.244614565,0.752759254,DB0660510024855_,0.284009819,-0.077294116,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,290731,DB08904,10015150,64,11546,16,3543,0.511001657,1.227417474,0.700229942,2.277695266,0.671348955,DB0890410015150_,0.398466224,0.204912347,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,certolizumab pegol,DB08904
,290736,DB01281,10020772,81,8851,6,1792,0.013226457,2.733084218,1.199979884,7.67658279,0.04448307,DB0128110020772_,3.112646622,1.005430722,female,10020772,Hypertension,10047065,Vascular disorders,Vasc,abatacept,DB01281
,290737,DB06273,10020772,69,5026,15,1395,0.504634673,1.276710287,0.720337614,2.410950043,0.665564402,DB0627310020772_,0.407119874,0.244286681,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,tocilizumab,DB06273
,290740,DB08904,10020772,69,11541,14,3545,0.193167425,1.513821469,0.842895684,2.916231601,0.340605472,DB0890410020772_,1.077030446,0.414637228,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,certolizumab pegol,DB08904
,290743,DB08895,10022086,121,27993,13,6633,0.004009087,2.205402812,1.241289694,4.264109184,0.017111121,DB0889510022086_,4.068026665,0.790910174,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,290744,DB08904,10022086,318,11292,53,3506,1.27132205879875e-05,1.862748931,1.385411333,2.547530122,0.000134042,DB0890410022086_,8.917356485,0.622053317,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,290749,DB08904,10022093,86,11524,10,3549,0.001543003,2.648477177,1.370777895,5.725357335,0.007874544,DB0890410022093_,4.844119958,0.973984825,NA,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,290776,DB06674,10047700,75,4431,8,1482,0.000749335,3.135292585,1.507193727,7.545211838,0.004329803,DB0667410047700_,5.442233207,1.142722498,female,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,golimumab,DB06674
,290777,DB08904,10047700,165,11445,26,3533,0.000774297,1.958850513,1.287567714,3.093058801,0.00445153,DB0890410047700_,5.414507441,0.672357828,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,certolizumab pegol,DB08904
,290909,DB00363,10038695,32,4596,40,6848,0.471212276,1.191967739,0.723604264,1.949180634,0.637458295,DB0036310038695_,0.450266424,0.175605503,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clozapine,DB00363
,290923,DB00005,10062003,35,128047,40,42379,1.35884854680178e-07,0.289597946,0.178566949,0.467651362,2.40278062917489e-06,DB0000510062003_,12.9388839,-1.239261711,male,10062003,Hernia repair,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,290932,DB00480,10018388,49,67379,21,67641,0.000749572,2.342525649,1.378569652,4.112469341,0.004330695,DB0048010018388_,5.442027299,0.851229684,NA,10018388,Glossodynia,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,290934,DB01241,10069339,16,927,37,1034,0.017035849,0.482513102,0.248855785,0.895930792,0.054481967,DB0124110069339_,2.909885506,-0.728747205,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,gemfibrozil,DB01241
,290965,DB00480,10033318,38,67390,54,67608,0.117295973,0.70598499,0.453470078,1.089233569,0.237108716,DB0048010033318_,1.439236524,-0.348161302,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,290968,DB14500,10033318,68,7741,41,4032,0.478484644,0.863888173,0.576721234,1.308265732,0.643784238,DB1450010033318_,0.440391644,-0.146311948,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,potassium,DB14500
,290974,DB00996,10001488,45,38908,76,22349,6.15029817775605e-09,0.340114817,0.22977303,0.498339973,1.45247607908641e-07,DB0099610001488_,15.74482591,-1.078472022,male,10001488,Aggression,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,291039,DB00003,10047461,30,2968,24,2569,0.78609524,1.081972279,0.609742398,1.939258838,0.883938884,DB0000310047461_,0.123367354,0.07878556,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,dornase alfa,DB00003
,291042,DB01015,10047461,33,9854,31,9350,1,1.010069752,0.59917729,1.706845996,1,DB0101510047461_,0,0.01001939,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,291090,DB08827,10024910,51,1111,25,557,1,1.022741769,0.614556458,1.742166066,1,DB0882710024910_,0,0.02248703,NA,10024910,Low density lipoprotein increased,10022891,Investigations,Inv,lomitapide,DB08827
,291099,DB08827,10047899,43,1119,23,559,0.791264481,0.933985335,0.544224783,1.641007,0.886981551,DB0882710047899_,0.119931097,-0.068294542,NA,10047899,Weight increased,10022891,Investigations,Inv,lomitapide,DB08827
,291126,DB00126,10013786,74,10097,30,5915,0.102463642,1.444985118,0.932369723,2.291240324,0.214687672,DB0012610013786_,1.538570997,0.368099022,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,ascorbic acid,DB00126
,291200,DB00860,10010264,35,1848,29,1467,0.899282597,0.958062585,0.565933435,1.63322989,0.956490275,DB0086010010264_,0.044484657,-0.042842174,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,prednisolone,DB00860
,291234,DB00243,10033425,36,1218,15,1611,9.47874518277212e-05,3.173146246,1.685374584,6.268098567,0.000761341,DB0024310033425_,7.180429307,1.154723602,female,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ranolazine,DB00243
,291262,DB00316,10024968,51,65423,40,36913,0.126520882,0.719408363,0.466130892,1.117156231,0.250839875,DB0031610024968_,1.382940491,-0.329326123,NA,10024968,Lower respiratory tract infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,291268,DB01067,10028735,33,4328,17,4806,0.010105921,2.155404666,1.164607787,4.132105885,0.035875761,DB0106710028735_,3.327693386,0.767978486,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glipizide,DB01067
,291280,DB00264,10052251,24,29583,36,24856,0.027642398,0.560154656,0.31958286,0.96542122,0.079438082,DB0026410052251_,2.532777398,-0.579542362,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,291380,DB00490,10037087,62,4008,16,1560,0.162398867,1.508190489,0.856498685,2.808917531,0.30056712,DB0049010037087_,1.20208419,0.41091058,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,buspirone,DB00490
,291382,DB00490,10048959,49,4021,12,1564,0.195505867,1.588176543,0.829723409,3.289398508,0.343672435,DB0049010048959_,1.0680663,0.46258653,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,291472,DB00341,10039906,95,11310,72,4996,0.000716692,0.582861804,0.423752166,0.804645473,0.004174219,DB0034110039906_,5.478827949,-0.539805164,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,cetirizine,DB00341
,291474,DB00215,10040753,149,10954,17,5259,4.47329536002256e-11,4.207132113,2.537734696,7.424074501,1.54915110063495e-09,DB0021510040753_,20.28555873,1.436781207,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,citalopram,DB00215
,291527,DB08895,10048592,55,28059,17,6629,0.366713562,0.764352093,0.436694132,1.405743122,0.536352891,DB0889510048592_,0.622962956,-0.268726742,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,291591,DB00046,10040070,31,5428,20,4672,0.328310273,1.334079805,0.735416667,2.473144169,0.49690024,DB0004610040070_,0.699365998,0.28824177,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,insulin lispro,DB00046
,291600,DB09035,10040070,28,4698,38,6652,0.900555603,1.043336313,0.615756312,1.748150595,0.956698706,DB0903510040070_,0.044266769,0.042423572,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,nivolumab,DB09035
,291635,DB11133,10008479,35,2396,24,1550,0.893336089,0.943429388,0.543086257,1.664736073,0.955535825,DB1113310008479_,0.045483023,-0.058233758,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,omega-3 fatty acids,DB11133
,291659,DB06273,10016256,147,4948,24,1386,0.014118607,1.715521332,1.103878955,2.774585766,0.04690736,DB0627310016256_,3.059580678,0.539717018,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,291727,DB01069,10016825,50,6650,7,2388,0.015023394,2.564969148,1.155147044,6.713557705,0.049376668,DB0106910016825_,3.008277282,0.941946451,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,promethazine,DB01069
,291729,DB13867,10016825,49,4501,10,2544,0.001620268,2.769181064,1.382681299,6.142302176,0.008181713,DB1386710016825_,4.805853769,1.018551632,female,10016825,Flushing,10047065,Vascular disorders,Vasc,fluticasone,DB13867
,291819,DB00281,10053425,50,11408,8,5663,0.001155768,3.102375074,1.45805825,7.581961493,0.006209371,DB0028110053425_,5.081695604,1.132167971,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,291822,DB00471,10053425,83,14106,12,5453,0.000518026,2.673513907,1.450480821,5.386342706,0.003178411,DB0047110053425_,5.75137393,0.983393677,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,291827,DB00028,10053482,42,13416,8,5607,0.042275068,2.194077482,1.016761275,5.414263107,0.110243678,DB0002810053482_,2.205062105,0.785761677,NA,10053482,Infusion site induration,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,291858,DB09140,10037087,86,3655,29,1769,0.107066218,1.43520653,0.92835871,2.277293892,0.221724288,DB0914010037087_,1.506320614,0.361308762,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,oxygen,DB09140
,291948,DB05676,10029331,45,47084,23,25306,0.899306682,1.051564149,0.622771067,1.821299691,0.956490275,DB0567610029331_,0.044484657,0.050278721,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,291954,DB01394,10037087,49,1391,24,1979,1.17982155022621e-05,2.903818691,1.73826191,4.973321982,0.000125477,DB0139410037087_,8.983389086,1.066026661,female,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,colchicine,DB01394
,292151,DB00950,10076309,40,4678,17,2039,1,1.025591074,0.566824749,1.934132951,1,DB0095010076309_,0,0.025269103,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fexofenadine,DB00950
,292235,DB00203,10007556,44,13834,23,8915,0.453873836,1.232780934,0.727908055,2.140334318,0.62142274,DB0020310007556_,0.475743687,0.209272539,NA,10007556,Cardiac failure acute,10007541,Cardiac disorders,Card,sildenafil,DB00203
,292236,DB00316,10007556,41,65433,27,36926,0.530041885,0.856957731,0.514529905,1.448895453,0.687176433,DB0031610007556_,0.375164204,-0.154366684,NA,10007556,Cardiac failure acute,10007541,Cardiac disorders,Card,acetaminophen,DB00316
,292237,DB00374,10007556,49,17667,18,5706,0.669201513,0.879198629,0.502658298,1.604927024,0.799162431,DB0037410007556_,0.224191061,-0.128744435,NA,10007556,Cardiac failure acute,10007541,Cardiac disorders,Card,treprostinil,DB00374
,292243,DB00695,10007556,71,27978,56,20472,0.719213594,0.927715512,0.64406286,1.341978188,0.834225382,DB0069510007556_,0.181251671,-0.075030154,NA,10007556,Cardiac failure acute,10007541,Cardiac disorders,Card,furosemide,DB00695
,292270,DB01592,10033318,39,6237,19,3048,1,1.00311386,0.564734824,1.841142181,1,DB0159210033318_,0,0.003109022,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,iron,DB01592
,292274,DB01592,10033557,55,6221,7,3060,0.000116684,3.864099211,1.75232292,10.07099445,0.000910638,DB0159210033557_,7.001365127,1.351728592,female,10033557,Palpitations,10007541,Cardiac disorders,Card,iron,DB01592
,292360,DB00136,10003239,40,2052,15,1667,0.009276156,2.165889179,1.16575903,4.236237403,0.033515295,DB0013610003239_,3.395753368,0.772830983,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,calcitriol,DB00136
,292365,DB00003,10019211,82,2916,63,2530,0.500329628,1.129259212,0.799570794,1.601317956,0.661919279,DB0000310019211_,0.412611666,0.121561853,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,dornase alfa,DB00003
,292415,DB00374,10059830,39,17677,16,5708,0.432457768,0.787090701,0.429436227,1.509901345,0.600864384,DB0037410059830_,0.50938602,-0.239411788,NA,10059830,Infusion site rash,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,292420,DB06403,10063829,44,21427,7,6654,0.1008518,1.951860837,0.871674901,5.138803283,0.212122073,DB0640310063829_,1.550593352,0.668783193,NA,10063829,Device malfunction,10077536,Product issues,Prod,ambrisentan,DB06403
,292426,DB00540,10070863,197,2286,100,991,0.236187052,0.854062328,0.659942768,1.110452599,0.393420574,DB0054010070863_,0.932876078,-0.157751104,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,nortriptyline,DB00540
,292462,DB06273,10018001,42,5053,12,1398,0.869411778,0.968338118,0.498809423,2.026311299,0.941900916,DB0627310018001_,0.059855195,-0.032173957,NA,10018001,Gastrointestinal perforation,10017947,Gastrointestinal disorders,Gastr,tocilizumab,DB06273
,292566,DB00572,10069339,57,2845,42,2084,1,0.994125646,0.652855943,1.524519949,1,DB0057210069339_,0,-0.005891676,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,atropine,DB00572
,292567,DB08875,10069339,13,630,38,1205,0.231029953,0.654481025,0.31748005,1.267152371,0.387173471,DB0887510069339_,0.948882441,-0.423912686,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,cabozantinib,DB08875
,292607,DB09140,10005483,49,3692,36,1762,0.061074057,0.649630421,0.412245844,1.032415372,0.145430228,DB0914010005483_,1.928058837,-0.431351661,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,oxygen,DB09140
,292625,DB00331,10005851,25,24921,35,20717,0.051259964,0.593805364,0.340544053,1.021208473,0.127379187,DB0033110005851_,2.06058692,-0.521203683,NA,10005851,Blood urea increased,10022891,Investigations,Inv,metformin,DB00331
,292663,DB00722,10028035,47,25356,25,26007,0.0089978,1.928231244,1.162522611,3.27010971,0.032716444,DB0072210028035_,3.419877449,0.656603129,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,lisinopril,DB00722
,292680,DB00331,10038683,31,24915,26,20726,1,0.991842422,0.569672912,1.73968904,1,DB0033110038683_,0,-0.008191033,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,292685,DB01234,10038683,55,31570,51,32837,0.561373612,1.121709494,0.752013142,1.675869259,0.713805322,DB0123410038683_,0.337145012,0.114853855,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,292708,DB00243,10007559,12,1242,47,1579,0.000268248,0.324716927,0.1560932,0.625002011,0.001841924,DB0024310007559_,6.296944359,-1.124801469,male,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,ranolazine,DB00243
,292765,DB01254,10054112,129,3338,143,3005,0.09449294,0.812132445,0.631752429,1.043202032,0.202476013,DB0125410054112_,1.597133852,-0.208091842,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,dasatinib,DB01254
,292790,DB01101,10013950,91,7498,69,3839,0.018295532,0.67525285,0.487175991,0.93957425,0.057578789,DB0110110013950_,2.85460102,-0.392668066,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,292807,DB00115,10061394,40,18385,13,10459,0.086074103,1.750391504,0.916614563,3.568727181,0.188471365,DB0011510061394_,1.668809192,0.55983948,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,292863,DB00193,10017533,54,19266,8,8694,0.001379436,3.045823054,1.439894332,7.414847417,0.007177052,DB0019310017533_,4.936866615,1.113771162,female,10017533,Fungal infection,10021881,Infections and infestations,Infec,tramadol,DB00193
,292922,DB00999,10022093,105,21325,18,12221,1.38382230310367e-07,3.342882284,2.014267002,5.861115377,2.44201203337227e-06,DB0099910022093_,12.92268825,1.206833394,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,292933,DB01175,10015090,45,10679,24,4868,0.518361936,0.854735701,0.509123646,1.468536056,0.677656446,DB0117510015090_,0.389114836,-0.156962979,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,293043,DB11089,10013946,69,10106,38,8369,0.050938561,1.503659594,0.996680477,2.299394412,0.126767665,DB1108910013946_,2.06539928,0.407901866,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,293079,DB00480,10066274,213,67215,220,67442,0.772913696,0.971445892,0.80059205,1.17861803,0.875823357,DB0048010066274_,0.132590855,-0.028969708,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,lenalidomide,DB00480
,293100,DB00722,10044066,37,25366,16,26016,0.003530399,2.371821543,1.286881388,4.567530233,0.015425602,DB0072210044066_,4.171726673,0.863658244,NA,10044066,Torsade de pointes,10007541,Cardiac disorders,Card,lisinopril,DB00722
,293171,DB06282,10013573,52,1488,19,514,0.89010111,0.945409558,0.543566147,1.710068601,0.954444894,DB0628210013573_,0.046625371,-0.056137051,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,levocetirizine,DB06282
,293249,DB00761,10021027,48,15259,19,8606,0.204625326,1.424809385,0.821429195,2.568496914,0.354623637,DB0076110021027_,1.03669823,0.35403804,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,293294,DB00620,10021097,51,4777,60,3072,0.001678346,0.546680719,0.367768531,0.809978272,0.008424581,DB0062010021097_,4.776601535,-0.603890341,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,triamcinolone,DB00620
,293384,DB06262,10046571,81,3719,102,4212,0.500727667,0.899415098,0.661095042,1.220286036,0.662286857,DB0626210046571_,0.412056498,-0.106010618,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,droxidopa,DB06262
,293423,DB00264,10062352,34,29573,25,24867,0.695303296,1.143569564,0.662286416,1.999917298,0.816560818,DB0026410062352_,0.202653883,0.134154567,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,metoprolol,DB00264
,293432,DB00996,10062352,74,38879,22,22403,0.005560432,1.938185802,1.190134802,3.278045642,0.022272988,DB0099610062352_,3.804380632,0.661752382,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,293461,DB08904,10054112,116,11494,60,3499,0.001232433,0.588568733,0.426256987,0.819788331,0.006537737,DB0890410054112_,5.030164122,-0.530061566,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,certolizumab pegol,DB08904
,293498,DB00028,10029331,33,13425,28,5587,0.007008411,0.490482992,0.287139245,0.843387176,0.026818474,DB0002810029331_,3.618664314,-0.712364675,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,293518,DB08910,10041834,16,16728,34,17454,0.022554084,0.491023884,0.252981708,0.914624046,0.067849396,DB0891010041834_,2.690464788,-0.711262508,NA,10041834,Squamous cell carcinoma of skin,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pomalidomide,DB08910
,293527,DB00181,10029331,63,9793,41,5830,0.684539558,0.914771548,0.6067957,1.392482284,0.809480038,DB0018110029331_,0.211363165,-0.08908092,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,baclofen,DB00181
,293529,DB00455,10029331,124,9277,74,5044,0.549266819,0.911090023,0.676240344,1.234721503,0.70359796,DB0045510029331_,0.351548166,-0.093113569,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,293547,DB06674,10001760,74,4432,9,1481,0.001959163,2.747348092,1.367080542,6.259157226,0.009575194,DB0667410001760_,4.64857953,1.010636116,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,golimumab,DB06674
,293582,DB11065,10000059,43,3143,23,2665,0.082038685,1.585109561,0.931465399,2.763195365,0.181783337,DB1106510000059_,1.704939757,0.460653529,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,pancrelipase amylase,DB11065
,293585,DB11065,10003549,60,3126,35,2653,0.096212433,1.454800264,0.940005027,2.282363773,0.205041672,DB1106510003549_,1.584542043,0.374868615,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pancrelipase amylase,DB11065
,293605,DB01275,10030124,70,3909,45,3304,0.15828383,1.314750262,0.888590205,1.962628903,0.295174917,DB0127510030124_,1.220187158,0.273646733,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,293611,DB08895,10061822,386,27728,56,6590,0.000320516,1.638159938,1.233507142,2.211667708,0.002130158,DB0889510061822_,6.151559073,0.493573623,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,293612,DB00316,10028164,91,65383,26,36927,0.001426664,1.976715461,1.266205451,3.186093355,0.00737533,DB0031610028164_,4.909614625,0.681436609,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,acetaminophen,DB00316
,293629,DB08908,10002948,43,10630,13,3266,1,1.016269726,0.535608943,2.062615258,1,DB0890810002948_,0,0.016138792,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,293653,DB00924,10040070,39,10123,13,4238,0.544398641,1.255911708,0.655479075,2.567083761,0.699407037,DB0092410040070_,0.357522393,0.227861769,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,cyclobenzaprine,DB00924
,293683,DB00230,10015916,66,19608,17,8634,0.055357956,1.709489411,0.990649241,3.110382901,0.134949667,DB0023010015916_,2.002853404,0.536194736,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,pregabalin,DB00230
,293731,DB00927,10029366,46,7451,27,4989,0.633188779,1.140780765,0.69331261,1.911146124,0.771855578,DB0092710029366_,0.258957822,0.13171291,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,famotidine,DB00927
,293754,DB00421,10011781,47,8856,7,5245,0.000107286,3.976260556,1.784271037,10.43702073,0.000847616,DB0042110011781_,7.073082696,1.380341819,female,10011781,Cystitis,10021881,Infections and infestations,Infec,spironolactone,DB00421
,293758,DB04868,10047895,21,1620,33,1483,0.05521994,0.582651867,0.318802133,1.04282053,0.134712157,DB0486810047895_,2.004614947,-0.540165412,NA,10047895,Weight decreased,10022891,Investigations,Inv,nilotinib,DB04868
,293781,DB06285,10062355,44,8806,7,1099,0.503273557,0.784486724,0.349401341,2.069446708,0.66441715,DB0628510062355_,0.408845089,-0.242725629,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,293782,DB00465,10020751,74,2030,21,862,0.110767696,1.496140745,0.904311816,2.575376636,0.227241278,DB0046510020751_,1.481742926,0.402888956,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ketorolac,DB00465
,293804,DB00635,10039674,43,33010,8,23786,9.00239873621985e-05,3.872953704,1.799502579,9.537443138,0.00072977,DB0063510039674_,7.2227806,1.354017447,female,10039674,Sciatica,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,293814,DB01104,10061920,42,15421,31,7255,0.059873912,0.63740646,0.390919266,1.049736599,0.143253756,DB0110410061920_,1.943137701,-0.450347742,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,293845,DB00188,10017955,18,7868,33,8795,0.093382972,0.609739189,0.322965369,1.11583513,0.200741886,DB0018810017955_,1.605735345,-0.494723972,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,293860,DB00787,10065553,23,16977,33,17215,0.229109255,0.706750512,0.396042375,1.241133152,0.384850254,DB0078710065553_,0.95490097,-0.347077558,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,acyclovir,DB00787
,293921,DB00250,10053762,42,784,32,778,0.286014947,1.302241887,0.793375348,2.155594014,0.450727113,DB0025010053762_,0.796893193,0.264087308,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,dapsone,DB00250
,294083,DB15566,10016256,43,964,26,636,0.802033366,1.091089025,0.647917889,1.869744323,0.892903305,DB1556610016256_,0.113276985,0.087176303,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,prednisolone acetate,DB15566
,294212,DB09035,10014581,25,4701,42,6648,0.535683362,0.841792202,0.490914216,1.415848666,0.692197615,DB0903510014581_,0.367883793,-0.172222087,NA,10014581,Encephalitis,10021881,Infections and infestations,Infec,nivolumab,DB09035
,294214,DB09035,10021036,69,4657,99,6591,1,0.986414027,0.712934446,1.35831356,1,DB0903510021036_,0,-0.013679107,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,nivolumab,DB09035
,294265,DB01307,10021097,39,2485,30,2039,0.808787818,1.066683204,0.643254988,1.78488146,0.896852337,DB0130710021097_,0.108864049,0.064554024,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,insulin detemir,DB01307
,294270,DB01020,10030124,35,1778,34,1844,0.808955511,1.067639059,0.643539459,1.772923428,0.896971703,DB0102010030124_,0.108730963,0.065449724,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,isosorbide mononitrate,DB01020
,294323,DB00331,10039117,38,24908,39,20713,0.361926423,0.810264576,0.504256196,1.300944936,0.531668232,DB0033110039117_,0.631735608,-0.210394448,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,294334,DB00169,10062262,46,38645,12,18163,0.06791667,1.801634928,0.938921967,3.737102581,0.157563078,DB0016910062262_,1.847929403,0.588694546,NA,10062262,Spinal operation,10042613,Surgical and medical procedures,Surg,cholecalciferol,DB00169
,294448,DB01104,10019301,33,15430,17,7269,0.762892645,0.914485476,0.494572016,1.751753687,0.868699858,DB0110410019301_,0.140757602,-0.089393694,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,sertraline,DB01104
,294459,DB00480,10040742,54,67374,47,67615,0.487582796,1.153043843,0.765291887,1.74280969,0.65139079,DB0048010040742_,0.428645525,0.142405266,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,294510,DB00924,10008469,69,10093,13,4238,0.005134365,2.228570843,1.219692866,4.399781171,0.020892762,DB0092410008469_,3.868352489,0.801360503,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,294657,DB00115,10062519,40,18385,11,10461,0.028911675,2.069029521,1.041342861,4.473071812,0.082285028,DB0011510062519_,2.497566112,0.727079667,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,294684,DB06262,10003549,165,3635,198,4116,0.628239139,0.94359347,0.758995522,1.171929068,0.767541229,DB0626210003549_,0.264563083,-0.058059852,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,294696,DB06262,10025482,194,3606,116,4198,1.47041629398532e-08,1.946792922,1.531860615,2.482915285,3.17844508942469e-07,DB0626210025482_,14.96170354,0.666183363,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,294700,DB06262,10041349,81,3719,91,4223,1,1.010737743,0.737312636,1.383532455,1,DB0626210041349_,0,0.010680503,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,294704,DB06262,10042772,140,3660,138,4176,0.245333917,1.157496903,0.904435132,1.481505239,0.404137051,DB0626210042772_,0.906001224,0.146259831,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,294709,DB06262,10044565,92,3708,96,4218,0.604858843,1.090130718,0.807102757,1.471696884,0.748052492,DB0626210044565_,0.290282127,0.086297614,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,294710,DB00190,10061822,30,3267,30,4644,0.188964682,1.421397819,0.826117434,2.445808874,0.335230093,DB0019010061822_,1.092938139,0.351640767,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,294715,DB06262,10061822,56,3744,47,4267,0.136128952,1.357868527,0.902522419,2.050906607,0.264301933,DB0626210061822_,1.330663143,0.305916211,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,294728,DB08910,10052904,41,16703,32,17456,0.241549644,1.338994054,0.822385767,2.197824048,0.399630677,DB0891010052904_,0.917214465,0.291918626,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,pomalidomide,DB08910
,294761,DB09054,10035664,26,398,33,548,0.786869522,1.084728968,0.612408693,1.903458066,0.884412272,DB0905410035664_,0.122831954,0.081330157,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,idelalisib,DB09054
,294847,DB00996,10011878,56,38897,23,22402,0.198468755,1.40225998,0.848705643,2.388520127,0.347239407,DB0099610011878_,1.057740802,0.338085206,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,gabapentin,DB00996
,294857,DB09053,10013709,31,2254,45,4007,0.401430328,1.224600214,0.746847117,1.984661339,0.571258216,DB0905310013709_,0.559913955,0.202614435,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ibrutinib,DB09053
,294869,DB01065,10013950,37,4294,34,3017,0.276833469,0.764640497,0.465710095,1.258928782,0.440319666,DB0106510013950_,0.820254302,-0.268349494,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,melatonin,DB01065
,294993,DB00471,10015090,71,14118,38,5427,0.107700469,0.718239487,0.477121291,1.096329319,0.222683772,DB0047110015090_,1.502002576,-0.330952218,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,295181,DB00199,10013573,48,2662,7,693,0.17856247,1.784832461,0.798282236,4.697010122,0.322080255,DB0019910013573_,1.132954525,0.579324552,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,erythromycin,DB00199
,295190,DB00316,10016970,116,65358,27,36926,1.04780017601488e-05,2.427301755,1.585426376,3.840428384,0.000113037,DB0031610016970_,9.087796718,0.886780252,NA,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,295234,DB04868,10003549,28,1613,34,1482,0.305501573,0.756716779,0.43968196,1.292727808,0.472283687,DB0486810003549_,0.750175442,-0.278766232,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,nilotinib,DB04868
,295251,DB00104,10069327,54,1427,34,1043,0.583001524,1.160762319,0.736046066,1.853267807,0.731116176,DB0010410069327_,0.313182904,0.149076961,NA,10069327,Product quality issue,10077536,Product issues,Prod,octreotide,DB00104
,295284,DB05676,10013710,32,47097,20,25309,0.662785796,0.859817286,0.4767699,1.586688972,0.794417715,DB0567610013710_,0.230145866,-0.151035371,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,295316,DB00887,10007515,27,2314,34,1781,0.067996741,0.611287247,0.353302009,1.048081022,0.157707079,DB0088710007515_,1.847015896,-0.492188305,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,bumetanide,DB00887
,295376,DB13867,10003658,48,4502,31,2523,0.556544435,0.867766326,0.539564956,1.414182945,0.70989596,DB1386710003658_,0.342636855,-0.14183281,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,fluticasone,DB13867
,295477,DB00814,10010144,139,8148,69,3346,0.218037238,0.827294413,0.613654085,1.123997994,0.371223827,DB0081410010144_,0.990950092,-0.189594646,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,meloxicam,DB00814
,295478,DB01068,10010144,1435,12328,567,6273,8.50760542187315e-07,1.287766941,1.162104058,1.428502106,1.2437286346715e-05,DB0106810010144_,11.29481163,0.252909665,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,295479,DB09068,10010144,36,2359,69,917,3.59809989762033e-15,0.202923376,0.130731285,0.310377853,2.25181085259406e-13,DB0906810010144_,29.12187149,-1.594926828,male,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,vortioxetine,DB09068
,295483,DB06605,10036018,30,14043,29,13004,0.896795382,0.957930921,0.555201112,1.655047087,0.95631736,DB0660510036018_,0.044665454,-0.042979611,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,apixaban,DB06605
,295514,DB09270,10046571,97,3017,26,2342,2.73931888420221e-07,2.895482271,1.854919095,4.668779446,4.50159405259488e-06,DB0927010046571_,12.31107899,1.063151685,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ubidecarenone,DB09270
,295558,DB00480,10061520,76,67352,75,67587,0.935255953,1.016871015,0.729180788,1.418359352,0.975485208,DB0048010061520_,0.024820282,0.01673028,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,295589,DB00887,10009033,41,2300,24,1791,0.313663767,1.33018097,0.781549614,2.310797647,0.481140708,DB0088710009033_,0.73159552,0.285315001,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bumetanide,DB00887
,295603,DB00887,10044565,30,2311,20,1795,0.66800546,1.16502838,0.637706043,2.172245727,0.798342817,DB0088710044565_,0.225217179,0.152745447,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,bumetanide,DB00887
,295738,DB00364,10010264,64,2686,16,1384,0.008329373,2.060743854,1.172065362,3.834367465,0.030741024,DB0036410010264_,3.482157234,0.723067012,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,sucralfate,DB00364
,295851,DB13867,10012174,61,4489,27,2527,0.316766638,1.27179107,0.793770183,2.087104201,0.484575066,DB1386710012174_,0.724482924,0.240426198,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,fluticasone,DB13867
,295855,DB01075,10013911,59,19889,22,11075,0.13068023,1.493326494,0.90083417,2.560959617,0.256749997,DB0107510013911_,1.359652441,0.401006178,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,295892,DB00996,10023003,50,38903,8,22417,0.000177684,3.601359274,1.693670184,8.7978634,0.001304224,DB0099610023003_,6.642147275,1.28131135,female,10023003,Irritable bowel syndrome,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,296122,DB00761,10028997,33,15274,22,8603,0.574662986,0.844880907,0.477648491,1.522127765,0.724362046,DB0076110028997_,0.322463948,-0.1685596,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,potassium chloride,DB00761
,296368,DB00761,10057362,32,15275,32,8593,0.025915141,0.562596938,0.333414064,0.949120029,0.075502047,DB0076110057362_,2.583595505,-0.575191825,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,296493,DB00588,10066152,34,16490,16,8452,0.881482875,1.089168965,0.58462711,2.114460079,0.95045981,DB0058810066152_,0.050809401,0.085414988,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,fluticasone propionate,DB00588
,296536,DB01097,10011906,44,6221,25,1478,0.001038097,0.418203555,0.249496183,0.715508005,0.005684661,DB0109710011906_,5.169983734,-0.871786992,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,296565,DB08895,10031282,56,28058,9,6637,0.343952283,1.471817497,0.722034576,3.38646919,0.513229018,DB0889510031282_,0.667033104,0.38649803,NA,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,296603,DB00874,10017955,18,3317,34,1942,3.87227392178119e-05,0.310025257,0.164350339,0.566326059,0.000354953,DB0087410017955_,7.94352569,-1.171101511,male,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,guaifenesin,DB00874
,296665,DB00451,10043417,132,47139,44,15375,0.930152541,0.978488597,0.690463021,1.410387238,0.971453642,DB0045110043417_,0.02896173,-0.021746146,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,296666,DB00678,10043417,35,15564,17,10707,0.26071865,1.416315011,0.772023484,2.697386093,0.422203106,DB0067810043417_,0.862268788,0.348058436,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,296754,DB00999,10061224,71,21359,35,12204,0.544186601,1.159096408,0.762332703,1.791813934,0.699245917,DB0099910061224_,0.357752786,0.147640743,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrochlorothiazide,DB00999
,296779,DB00476,10076309,126,17131,43,6134,0.860961883,1.049185716,0.735802339,1.521835289,0.934772841,DB0047610076309_,0.06745173,0.048014355,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,296848,DB01373,10076308,85,22635,23,7358,0.501727701,1.201340826,0.749901793,1.997541517,0.663172134,DB0137310076308_,0.410720694,0.183438288,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,296851,DB00295,10022000,75,14588,51,9551,0.855300515,0.96279383,0.665022027,1.403805889,0.929912891,DB0029510022000_,0.072664363,-0.037915981,NA,10022000,Influenza,10021881,Infections and infestations,Infec,morphine,DB00295
,296854,DB01156,10022000,109,13513,37,6291,0.107959815,1.371506785,0.935421112,2.051637151,0.223021357,DB0115610022000_,1.500487742,0.315909979,NA,10022000,Influenza,10021881,Infections and infestations,Infec,bupropion,DB01156
,296856,DB11089,10022000,110,10065,73,8334,0.156244989,1.247682358,0.918349071,1.703608653,0.292393682,DB1108910022000_,1.229654157,0.221287717,NA,10022000,Influenza,10021881,Infections and infestations,Infec,docusate,DB11089
,296950,DB00016,10066152,24,2738,31,2259,0.103677311,0.638817379,0.35764213,1.128169565,0.216514371,DB0001610066152_,1.530098356,-0.448136658,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,erythropoietin,DB00016
,296967,DB05679,10016322,36,6895,14,4895,0.061049435,1.825452872,0.959588492,3.667956682,0.145391357,DB0567910016322_,1.928326158,0.601828105,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,297095,DB01097,10061822,225,6040,33,1470,0.006251837,1.659271036,1.142067694,2.48052288,0.024462902,DB0109710061822_,3.710597516,0.506378371,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,297096,DB01281,10061822,126,8806,9,1789,0.000707578,2.844019692,1.447716303,6.375754716,0.004130288,DB0128110061822_,5.489408196,1.045218436,female,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,297097,DB06674,10061822,68,4438,8,1482,0.002940615,2.83822187,1.357434574,6.854703261,0.013291043,DB0667410061822_,4.320664903,1.043177754,female,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,golimumab,DB06674
,297102,DB00028,10037855,41,13417,12,5603,0.364765559,1.426847558,0.734994141,2.98460776,0.534387111,DB0002810037855_,0.626634775,0.355467506,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,human immunoglobulin g,DB00028
,297131,DB00230,10046555,32,19642,30,8621,0.003439563,0.468170095,0.275306187,0.798116944,0.015113494,DB0023010046555_,4.19216726,-0.758923598,NA,10046555,Urinary retention,10038359,Renal and urinary disorders,Renal,pregabalin,DB00230
,297144,DB00377,10012174,46,1073,27,696,0.715498747,1.105068647,0.665525159,1.867240215,0.831555925,DB0037710012174_,0.184456725,0.099907457,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,palonosetron,DB00377
,297159,DB05679,10047700,79,6852,38,4871,0.048052816,1.477849057,0.98963698,2.241390314,0.121447731,DB0567910047700_,2.108271308,0.390587691,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ustekinumab,DB05679
,297324,DB01248,10046571,52,2648,18,1356,0.162714126,1.479222771,0.847183016,2.697938249,0.300983063,DB0124810046571_,1.200701286,0.391516795,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,docetaxel,DB01248
,297332,DB00863,10037153,121,10552,28,5812,9.73121608519084e-06,2.38011629,1.565200367,3.734745679,0.000106135,DB0086310037153_,9.1508,0.867149348,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,297485,DB00853,10035528,49,1772,40,2226,0.051851479,1.538667789,0.987654276,2.40967999,0.128528493,DB0085310035528_,2.051604667,0.43091697,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,temozolomide,DB00853
,297521,DB01238,10029898,36,5214,39,3463,0.043453549,0.613136953,0.377915805,0.992279161,0.112549952,DB0123810029898_,2.184358137,-0.489166953,NA,10029898,Obsessive-compulsive disorder,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,297557,DB00563,10041466,43,46603,20,15328,0.19180785,0.707152135,0.406925325,1.269320264,0.338912969,DB0056310041466_,1.082011933,-0.346509453,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,297560,DB00635,10062132,45,33008,13,23781,0.003038696,2.493844038,1.321760551,5.040239532,0.013661846,DB0063510062132_,4.293148262,0.91382531,NA,10062132,Tooth extraction,10042613,Surgical and medical procedures,Surg,prednisone,DB00635
,297581,DB05259,10054112,63,11207,20,2708,0.269342121,0.761165724,0.453139956,1.331657642,0.43188395,DB0525910054112_,0.839598362,-0.272904174,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,glatiramer,DB05259
,297623,DB00813,10028600,17,10555,33,10135,0.022492352,0.494672378,0.258236982,0.914654552,0.067706308,DB0081310028600_,2.69257593,-0.703859597,NA,10028600,Myocardial ischaemia,10007541,Cardiac disorders,Card,fentanyl,DB00813
,297671,DB00620,10005750,38,4790,19,3113,0.414830031,1.299747114,0.729414615,2.391493572,0.584043887,DB0062010005750_,0.537779149,0.262169718,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,triamcinolone,DB00620
,297712,DB00264,10000486,19,29588,31,24861,0.022851761,0.514997799,0.27480806,0.941142412,0.068548762,DB0026410000486_,2.680209926,-0.663592652,NA,10000486,Acidosis,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,297840,DB00863,10037423,45,10628,22,5818,0.70291527,1.119733528,0.657731809,1.960067243,0.821745591,DB0086310037423_,0.196324431,0.113090735,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,297846,DB14513,10037423,32,7145,24,3540,0.153792305,0.660612441,0.376418872,1.174034458,0.289199508,DB1451310037423_,1.240638489,-0.414587933,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium,DB14513
,297854,DB00727,10047942,31,3812,42,4131,0.410265392,0.799884666,0.485062156,1.306040687,0.579697665,DB0072710047942_,0.545248578,-0.22328773,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,nitroglycerin,DB00727
,297945,DB00736,10047340,44,10547,17,5536,0.344629694,1.358515507,0.759839775,2.538765668,0.514020967,DB0073610047340_,0.665491222,0.306392565,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,esomeprazole,DB00736
,297959,DB00480,10019063,80,67348,87,67575,0.642446331,0.922663404,0.672299726,1.264819167,0.778906911,DB0048010019063_,0.249863739,-0.080490787,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,298062,DB00480,10052239,107,67321,98,67564,0.52982333,1.095761049,0.82509541,1.456637421,0.687028254,DB0048010052239_,0.375379861,0.091449144,NA,10052239,Full blood count increased,10022891,Investigations,Inv,lenalidomide,DB00480
,298064,DB00153,10035598,38,7385,20,3419,0.671695366,0.879652186,0.498281797,1.598077255,0.800776157,DB0015310035598_,0.222173826,-0.128228693,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,298102,DB00254,10076309,40,5895,30,3358,0.263219223,0.759555647,0.460404177,1.265369557,0.425008741,DB0025410076309_,0.855645544,-0.275021691,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,doxycycline,DB00254
,298153,DB09079,10035664,29,628,31,846,0.425124665,1.260020009,0.724424078,2.186060968,0.593893422,DB0907910035664_,0.5210554,0.231127601,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,nintedanib,DB09079
,298199,DB00581,10041349,35,2078,26,2043,0.303774056,1.323388247,0.771012652,2.298452081,0.470324619,DB0058110041349_,0.754332144,0.280195302,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,lactulose,DB00581
,298204,DB01234,10048334,37,31588,23,32865,0.053113908,1.673704621,0.968306305,2.951145662,0.130849531,DB0123410048334_,2.033707233,0.515039506,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,298233,DB08932,10029148,45,19398,21,6576,0.256012655,0.726446956,0.423483553,1.284837502,0.416781148,DB0893210029148_,0.875194019,-0.319589811,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,macitentan,DB08932
,298357,DB00203,10001760,63,13815,14,8924,9.34426015092784e-05,2.90670235,1.609781673,5.620806273,0.00075307,DB0020310001760_,7.191351976,1.067019226,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,sildenafil,DB00203
,298405,DB00178,10048959,42,1395,30,1650,0.041560256,1.655624245,1.005892458,2.755367937,0.108865547,DB0017810048959_,2.21764167,0.504178125,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ramipril,DB00178
,298437,DB00275,10048959,65,1995,19,1218,0.004112312,2.088221846,1.229465529,3.706639672,0.017469436,DB0027510048959_,4.047302454,0.736312913,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,olmesartan,DB00275
,298454,DB00575,10015150,37,5207,16,3813,0.093447236,1.693307089,0.917462189,3.265426719,0.200822548,DB0057510015150_,1.605333604,0.526683474,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,clonidine,DB00575
,298460,DB00472,10061623,47,10712,25,4287,0.242460982,0.752393128,0.453121353,1.277388009,0.400677078,DB0047210061623_,0.914599467,-0.284496315,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,298461,DB00575,10061623,41,5203,23,3806,0.374122754,1.303942024,0.762796217,2.280579953,0.543950913,DB0057510061623_,0.608896269,0.265392003,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,298473,DB01234,10017412,64,31561,90,32798,0.075512756,0.73898806,0.527587668,1.029947754,0.170654486,DB0123410017412_,1.768114314,-0.302473516,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,dexamethasone,DB01234
,298475,DB11089,10017412,39,10136,31,8376,0.904747107,1.039620662,0.631485993,1.724941511,0.957648198,DB1108910017412_,0.043274794,0.038855899,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,docusate,DB11089
,298523,DB08932,10016100,69,19374,33,6564,0.110193216,0.70841993,0.460968863,1.108688145,0.226327694,DB0893210016100_,1.485771354,-0.34471824,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,298533,DB08932,10039117,53,19390,22,6575,0.426071481,0.816892174,0.48794475,1.411673485,0.594773566,DB0893210039117_,0.519574506,-0.202248171,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,298539,DB08932,10063829,64,19379,27,6570,0.335598343,0.803614532,0.504650883,1.312166097,0.504766672,DB0893210063829_,0.683658992,-0.218635563,NA,10063829,Device malfunction,10077536,Product issues,Prod,macitentan,DB08932
,298677,DB00999,10024774,56,21374,22,12217,0.157156669,1.454921176,0.873719621,2.503641277,0.293677169,DB0099910024774_,1.225274181,0.374951724,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,298689,DB00455,10067482,35,9366,15,5103,0.463358314,1.27131591,0.675780793,2.507828865,0.630549211,DB0045510067482_,0.461164075,0.240052514,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,298829,DB00019,10020642,338,18674,326,9203,3.06464280877421e-17,0.510961113,0.436603616,0.598044713,2.43734148951982e-15,DB0001910020642_,33.6478685,-0.671461792,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,pegfilgrastim,DB00019
,298843,DB00868,10022437,42,2942,17,1629,0.338105359,1.367888804,0.759289523,2.571695225,0.507211104,DB0086810022437_,0.678827983,0.313268532,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,benzonatate,DB00868
,298846,DB09020,10022437,37,1917,14,1590,0.010675678,2.191542728,1.152277128,4.404934631,0.037509717,DB0902010022437_,3.283155256,0.784605738,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,bisacodyl,DB09020
,298910,DB00863,10038153,35,10638,29,5811,0.115209281,0.659256354,0.391040332,1.119372598,0.233961135,DB0086310038153_,1.452600267,-0.416642816,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,ranitidine,DB00863
,298947,DB00927,10046306,53,7444,28,4988,0.363035572,1.268320157,0.786665604,2.085629777,0.53255888,DB0092710046306_,0.630061815,0.237693314,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,famotidine,DB00927
,298965,DB00863,10047461,49,10624,29,5811,0.723403866,0.924194992,0.571641188,1.519021911,0.837386203,DB0086310047461_,0.177469901,-0.078832199,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,ranitidine,DB00863
,298982,DB01225,10047899,45,4999,31,4609,0.249024119,1.338321382,0.826842909,2.19176448,0.408431857,DB0122510047899_,0.895430192,0.291416129,NA,10047899,Weight increased,10022891,Investigations,Inv,enoxaparin,DB01225
,299065,DB01065,10061818,50,4281,25,3026,0.194486872,1.413623255,0.855925849,2.39041756,0.342380781,DB0106510061818_,1.071831768,0.346156092,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,299066,DB01115,10061818,32,3568,27,2241,0.283133277,0.744448332,0.430760074,1.295375867,0.447446756,DB0111510061818_,0.804197729,-0.295111829,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,299083,DB01075,10013754,42,19906,32,11065,0.183035662,0.729601902,0.449410972,1.194794659,0.327697604,DB0107510013754_,1.115664035,-0.315256233,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,299212,DB00374,10007815,96,17620,28,5696,0.67637424,1.108345287,0.720149033,1.756276631,0.80384645,DB0037410007815_,0.21834701,0.102868171,NA,10007815,Catheterisation cardiac,10022891,Investigations,Inv,treprostinil,DB00374
,299217,DB00563,10024670,131,46515,67,15281,0.00384794,0.642331013,0.474692737,0.876128058,0.016533403,DB0056310024670_,4.102372534,-0.442651512,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,methotrexate,DB00563
,299262,DB00341,10007739,45,11360,19,5049,1,1.052651133,0.602644917,1.907723576,1,DB0034110007739_,0,0.051311871,NA,10007739,Cataract,10015919,Eye disorders,Eye,cetirizine,DB00341
,299317,DB00586,10031161,75,7034,14,2791,0.008803322,2.125510502,1.188957106,4.080584589,0.032142703,DB0058610031161_,3.437569821,0.75401201,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,diclofenac,DB00586
,299334,DB00051,10061225,36,25695,16,11404,1,0.998595883,0.539938103,1.928226218,1,DB0005110061225_,0,-0.001405104,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,299388,DB00814,10006002,42,8245,10,3405,0.127321165,1.734433907,0.855099701,3.881378893,0.251897328,DB0081410006002_,1.378733702,0.550681082,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,299393,DB06643,10061822,52,52369,26,7489,1.58217451751071e-06,0.286038291,0.175259417,0.477501878,2.16038738663736e-05,DB0664310061822_,10.74263791,-1.251629591,male,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,299406,DB00338,10073317,56,33618,29,22243,0.318884614,1.277637697,0.801820031,2.076010207,0.48699312,DB0033810073317_,0.719505284,0.245012823,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,299410,DB00455,10029366,45,9356,18,5100,0.29259804,1.362734163,0.772314301,2.503978572,0.458175829,DB0045510029366_,0.780502261,0.309493096,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,loratadine,DB00455
,299415,DB08881,10037660,36,587,53,758,0.582501763,0.877208005,0.550020783,1.385418869,0.730646315,DB0888110037660_,0.313825774,-0.131011136,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,vemurafenib,DB08881
,299439,DB00959,10028810,88,7990,25,4977,0.000294184,2.192497835,1.390427435,3.574328959,0.001985781,DB0095910028810_,6.221743151,0.785041458,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,299440,DB00423,10037844,59,2408,17,1023,0.203519202,1.474299525,0.842806231,2.711619063,0.353324552,DB0042310037844_,1.040368234,0.388182979,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,methocarbamol,DB00423
,299449,DB00656,10001551,48,11965,15,6604,0.063941181,1.766168282,0.97136466,3.398381288,0.150559342,DB0065610001551_,1.893397972,0.568812388,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,trazodone,DB00656
,299452,DB00656,10003481,49,11964,17,6602,0.121316439,1.590509017,0.899219365,2.948369494,0.243317889,DB0065610003481_,1.413386505,0.464054102,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,trazodone,DB00656
,299479,DB09037,10051398,267,2259,307,2528,0.790675594,0.973270899,0.814808472,1.162018521,0.886605008,DB0903710051398_,0.120355708,-0.027092819,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pembrolizumab,DB09037
,299498,DB00437,10061822,48,6873,55,11491,0.065662045,1.459035522,0.968485619,2.191605209,0.153593206,DB0043710061822_,1.873447693,0.377775616,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,299510,DB01115,10037400,33,3567,29,2239,0.191909692,0.714337627,0.419244134,1.223169664,0.339047335,DB0111510037400_,1.081615549,-0.336399562,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nifedipine,DB01115
,299537,DB00091,10012174,44,5466,18,2652,0.589084792,1.185957756,0.669872889,2.185182348,0.735883552,DB0009110012174_,0.30668339,0.170550681,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,cyclosporine,DB00091
,299572,DB00115,10023547,108,18317,79,10393,0.093101735,0.775704952,0.574371449,1.051488335,0.200262625,DB0011510023547_,1.60812565,-0.253983048,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,cyanocobalamin,DB00115
,299575,DB00230,10023547,36,19638,22,8629,0.253070119,0.719022435,0.411408272,1.283848867,0.413459805,DB0023010023547_,0.883194976,-0.329862719,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,pregabalin,DB00230
,299576,DB00335,10023547,33,8433,21,5444,1,1.014449464,0.569042956,1.847137219,1,DB0033510023547_,0,0.014346066,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,atenolol,DB00335
,299581,DB00588,10023547,45,16479,37,8431,0.035302789,0.622235421,0.393477898,0.989552293,0.0960594,DB0058810023547_,2.342788528,-0.474436768,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,fluticasone propionate,DB00588
,299595,DB00115,10040844,83,18342,38,10434,0.297588178,1.242536172,0.836033235,1.876736157,0.463490964,DB0011510040844_,0.768968389,0.217154591,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,299600,DB00476,10040844,38,17219,20,6157,0.178613786,0.679395611,0.385170495,1.233386191,0.322150709,DB0047610040844_,1.132735803,-0.386551683,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,duloxetine,DB00476
,299603,DB00788,10040844,35,9321,20,5041,0.88767221,0.946442309,0.530815848,1.73213425,0.953432958,DB0078810040844_,0.047686168,-0.055045262,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,naproxen,DB00788
,299658,DB00169,10017367,58,38633,36,18139,0.185883689,0.756427204,0.490474157,1.180913632,0.331307189,DB0016910017367_,1.104709271,-0.279148978,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,299662,DB00381,10017367,42,29318,24,22863,0.263984928,1.364689591,0.807301065,2.356807311,0.425865764,DB0038110017367_,0.853631089,0.310926997,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,299720,DB01225,10013710,30,5014,23,4617,0.581978368,1.201048011,0.673460408,2.16859533,0.730181451,DB0122510013710_,0.314462213,0.183194518,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,enoxaparin,DB01225
,299748,DB01592,10066152,39,6237,12,3055,0.179486297,1.591838653,0.815118892,3.3444979,0.323225358,DB0159210066152_,1.129405497,0.464889734,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,iron,DB01592
,299768,DB11093,10011224,42,1615,8,652,0.056272279,2.118930418,0.975834248,5.254379174,0.136588498,DB1109310011224_,1.990782537,0.750911441,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium citrate,DB11093
,299839,DB08895,10028596,75,28039,43,6603,9.75870413166852e-06,0.410757502,0.278378709,0.612924732,0.000106346,DB0889510028596_,9.148808784,-0.889752257,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,tofacitinib,DB08895
,299906,DB00091,10061822,46,5464,12,2658,0.066508874,1.864625557,0.970045612,3.873713219,0.155063487,DB0009110061822_,1.863920654,0.623060259,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,299913,DB01015,10064848,56,9831,40,9341,0.183687822,1.330197669,0.869945493,2.050743302,0.328563076,DB0101510064848_,1.113026446,0.285327555,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,sulfamethoxazole,DB01015
,299924,DB00480,10067671,28,67400,39,67623,0.221480501,0.720328748,0.426852066,1.201092423,0.375358005,DB0048010067671_,0.979875029,-0.328047576,NA,10067671,Disease complication,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,299925,DB01285,10010264,51,1225,20,589,0.518399224,1.225921136,0.710457288,2.192091351,0.67766909,DB0128510010264_,0.389096178,0.203692509,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,corticotropin,DB01285
,299997,DB08896,10025482,29,794,38,1002,0.901050371,0.963092023,0.567401925,1.619387354,0.956856375,DB0889610025482_,0.044101977,-0.037606313,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,regorafenib,DB08896
,300016,DB00343,10003662,43,8693,39,5056,0.050551016,0.641320281,0.405388752,1.017268864,0.126006019,DB0034310003662_,2.071425607,-0.444226289,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,diltiazem,DB00343
,300050,DB00514,10002855,41,2125,12,1524,0.004734944,2.449801936,1.258021879,5.138104593,0.019576687,DB0051410002855_,3.933415884,0.896007179,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,dextromethorphan,DB00514
,300059,DB00555,10057667,47,7000,14,3472,0.101834932,1.665069572,0.899715794,3.279523532,0.213685482,DB0055510057667_,1.543250056,0.509866908,NA,10057667,Bipolar disorder,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,300120,DB00678,10048334,52,15547,24,10700,0.128008807,1.491154367,0.902227015,2.531168433,0.252852747,DB0067810048334_,1.374947989,0.399550563,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,300121,DB08868,10048334,71,9131,17,2494,0.697022654,1.140728975,0.663396269,2.070087666,0.817711743,DB0886810048334_,0.201245397,0.13166751,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,fingolimod,DB08868
,300142,DB00421,10003481,53,8850,25,5227,0.411063191,1.25212403,0.76343653,2.105409083,0.580403737,DB0042110003481_,0.54403132,0.224841333,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,spironolactone,DB00421
,300149,DB00682,10012267,39,19420,14,16350,0.005359424,2.34521973,1.245205829,4.677580999,0.021619468,DB0068210012267_,3.834161063,0.852379099,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,300152,DB08932,10012601,77,19366,24,6573,0.818756667,1.088933996,0.680306006,1.802682082,0.903295656,DB0893210012601_,0.101705364,0.085199232,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,macitentan,DB08932
,300167,DB00437,10005724,39,6882,40,11506,0.035435287,1.629985681,1.020262456,2.602491625,0.096355093,DB0043710005724_,2.339715026,0.48857123,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,allopurinol,DB00437
,300219,DB09153,10047899,77,7722,33,5666,0.008835056,1.712007345,1.123097665,2.662060336,0.032236183,DB0915310047899_,3.434665775,0.537666568,NA,10047899,Weight increased,10022891,Investigations,Inv,sodium chloride,DB09153
,300263,DB00203,10005364,61,13817,42,8896,0.761950463,0.935110836,0.620365572,1.421438576,0.868097088,DB0020310005364_,0.141451718,-0.067090215,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,sildenafil,DB00203
,300311,DB01068,10037423,39,13724,31,6809,0.056137418,0.624174225,0.379118709,1.035653441,0.136336694,DB0106810037423_,1.992627762,-0.471325743,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,300376,DB00758,10067482,22,8278,31,10043,0.678937134,0.86099915,0.474588338,1.53704277,0.805653035,DB0075810067482_,0.216102106,-0.149661762,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,300385,DB05679,10022437,35,6896,17,4892,0.207892494,1.460476483,0.795490631,2.783349541,0.358748306,DB0567910022437_,1.025134234,0.37876274,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ustekinumab,DB05679
,300410,DB00787,10004146,16,16984,46,17202,0.000178148,0.352277553,0.186077035,0.634298091,0.001307262,DB0078710004146_,6.639820499,-1.043335911,male,10004146,Basal cell carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acyclovir,DB00787
,300460,DB00424,10013709,48,1146,13,415,0.458845277,1.336835636,0.704092545,2.718162066,0.626223324,DB0042410013709_,0.468048223,0.290305356,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,hyoscyamine,DB00424
,300463,DB00904,10013774,56,23013,14,14442,0.001241925,2.510170581,1.378466837,4.884907828,0.006578596,DB0090410013774_,5.023933884,0.920350711,NA,10013774,Dry eye,10015919,Eye disorders,Eye,ondansetron,DB00904
,300505,DB00213,10014062,38,18857,17,13404,0.131633403,1.588875255,0.874928891,3.003441377,0.25806836,DB0021310014062_,1.354530768,0.463026379,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,300512,DB00695,10014062,33,28016,21,20507,0.680354614,1.150213131,0.64575439,2.092687587,0.80661785,DB0069510014062_,0.214905267,0.139947257,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,300515,DB01076,10014062,31,25716,36,25547,0.543196077,0.855455525,0.511567647,1.423016638,0.698408241,DB0107610014062_,0.358951474,-0.156121175,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,300558,DB01075,10038669,142,19806,89,11008,0.371364917,0.886775103,0.674845308,1.170469945,0.541008758,DB0107510038669_,0.614319811,-0.120163877,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,300559,DB01076,10038669,31,25716,38,25545,0.401304868,0.810369695,0.487395401,1.337927416,0.57111987,DB0107610038669_,0.560156161,-0.210264722,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,300612,DB00227,10016322,48,2419,24,1779,0.148403726,1.47072599,0.8794918,2.520269034,0.281788048,DB0022710016322_,1.266600095,0.38575615,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,lovastatin,DB00227
,300624,DB00451,10039509,41,47230,10,15409,0.51542649,1.337622644,0.658732535,2.995600454,0.675204848,DB0045110039509_,0.392739155,0.290893892,NA,10039509,Scab,10040785,Skin and subcutaneous tissue disorders,Skin,levothyroxine,DB00451
,300649,DB00343,10033433,118,8618,32,5063,5.47066472880991e-05,2.166263624,1.452546614,3.315442492,0.000476937,DB0034310033433_,7.648126729,0.773003851,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,diltiazem,DB00343
,300654,DB00641,10044034,53,14071,21,12454,0.00148341,2.233639842,1.323828981,3.901116002,0.007621468,DB0064110044034_,4.876786237,0.803632471,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,simvastatin,DB00641
,300679,DB00213,10033433,90,18805,23,13398,3.09687239428945e-06,2.787801584,1.746678237,4.621502739,3.89479860688508e-05,DB0021310033433_,10.15328349,1.025253322,female,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,300700,DB00758,10068319,53,8247,33,10041,0.002282158,1.955335967,1.241429463,3.120947965,0.010833757,DB0075810068319_,4.525088364,0.670562029,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clopidogrel,DB00758
,300714,DB00227,10017577,42,2425,19,1784,0.089470676,1.626037729,0.92145044,2.970978443,0.194430715,DB0022710017577_,1.637679399,0.486146214,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,lovastatin,DB00227
,300737,DB08932,10007556,65,19378,23,6574,0.902280789,0.958750771,0.587276953,1.618047782,0.957195726,DB0893210007556_,0.043747388,-0.042124122,NA,10007556,Cardiac failure acute,10007541,Cardiac disorders,Card,macitentan,DB08932
,300744,DB08932,10020642,108,19335,23,6574,0.043531765,1.596460764,1.009749724,2.6273523,0.112693401,DB0893210020642_,2.183084413,0.467789156,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,macitentan,DB08932
,300993,DB00480,10029446,15,67413,40,67622,0.001014452,0.376143609,0.193037017,0.696047403,0.005570849,DB0048010029446_,5.190207867,-0.977784269,NA,10029446,Nocturia,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,301000,DB01137,10006002,36,7736,17,5576,0.164317546,1.526322322,0.834431501,2.900924294,0.303189547,DB0113710006002_,1.193397101,0.422861131,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,301098,DB01043,10010264,26,1375,42,1368,0.064897528,0.616004638,0.360402748,1.034987125,0.152279194,DB0104310010264_,1.882039643,-0.484500786,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,memantine,DB01043
,301105,DB01043,10061422,15,1386,38,1372,0.001995373,0.390859057,0.198791804,0.731341665,0.009703624,DB0104310061422_,4.635255839,-0.939408251,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,memantine,DB01043
,301215,DB00758,10057362,23,8277,32,10042,0.68479686,0.872031482,0.486839288,1.538850816,0.809622937,DB0075810057362_,0.21118665,-0.136929753,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,301307,DB06282,10025482,46,1494,18,515,0.663604376,0.880999863,0.495696344,1.629721639,0.795097139,DB0628210025482_,0.229290985,-0.126697809,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,levocetirizine,DB06282
,301338,DB00497,10027599,135,19132,45,16330,7.65180937280921e-09,2.560475829,1.813696397,3.675194133,1.76350556215949e-07,DB0049710027599_,15.55079203,0.940193112,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,301361,DB06186,10021114,35,2174,46,3600,0.301732431,1.259880107,0.785157935,2.00583056,0.468059663,DB0618610021114_,0.759159506,0.231016564,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,ipilimumab,DB06186
,301406,DB01162,10019211,10,263,45,1657,0.32357714,1.399814618,0.621192205,2.861431678,0.492014504,DB0116210019211_,0.709247083,0.336339812,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,terazosin,DB01162
,301424,DB01115,10047899,53,3547,28,2240,0.491702408,1.195305614,0.740048643,1.969021783,0.654776767,DB0111510047899_,0.423460916,0.178401897,NA,10047899,Weight increased,10022891,Investigations,Inv,nifedipine,DB01115
,301610,DB00410,10019211,104,1501,36,973,0.001249057,1.872256227,1.258304782,2.841571191,0.006608587,DB0041010019211_,5.019385403,0.627144242,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,mupirocin,DB00410
,301726,DB00476,10007617,83,17174,45,6132,0.026782352,0.658574425,0.45224787,0.970044375,0.077513117,DB0047610007617_,2.557308099,-0.417677742,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,duloxetine,DB00476
,301832,DB00381,10043417,41,29319,40,22847,0.315511941,0.798745219,0.503748905,1.267394221,0.483147764,DB0038110043417_,0.727432743,-0.224713258,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,301875,DB00333,10048959,36,3035,17,3135,0.008209501,2.18716763,1.194140524,4.161877676,0.030421312,DB0033310048959_,3.492611868,0.782607387,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,methadone,DB00333
,301901,DB00480,10061218,62,67366,45,67617,0.100761748,1.382902344,0.926864269,2.077709399,0.212018519,DB0048010061218_,1.551081654,0.324184439,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,301909,DB01377,10005750,41,3755,16,2654,0.043131492,1.810990118,0.992004583,3.464507923,0.111931617,DB0137710005750_,2.189867155,0.593873722,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,magnesium oxide,DB01377
,301933,DB00136,10047899,39,2053,14,1668,0.007820299,2.262808842,1.197083811,4.527807006,0.02924199,DB0013610047899_,3.532149592,0.816606892,NA,10047899,Weight increased,10022891,Investigations,Inv,calcitriol,DB00136
,301934,DB00864,10047899,35,6834,43,8349,1,0.99439555,0.617043656,1.592609888,1,DB0086410047899_,0,-0.005620214,NA,10047899,Weight increased,10022891,Investigations,Inv,tacrolimus,DB00864
,301944,DB00264,10065154,163,29444,143,24749,0.730044159,0.958085379,0.760192573,1.208670114,0.842888988,DB0026410065154_,0.170920016,-0.042818382,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,metoprolol,DB00264
,301947,DB00864,10065154,40,6829,42,8350,0.505949979,1.164487463,0.735085915,1.842192646,0.666761686,DB0086410065154_,0.40532259,0.152281044,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,tacrolimus,DB00864
,301948,DB01068,10065154,71,13692,16,6824,0.002826336,2.211546435,1.271462807,4.080080095,0.01287191,DB0106810065154_,4.352707853,0.793692015,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,clonazepam,DB01068
,301949,DB01285,10065154,38,1238,15,594,0.655087362,1.215360575,0.647008312,2.39818348,0.788793665,DB0128510065154_,0.237250507,0.195040802,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,corticotropin,DB01285
,301951,DB00687,10010264,33,953,29,1056,0.438842859,1.260772269,0.735985365,2.170271725,0.607200324,DB0068710010264_,0.49889652,0.231724445,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,fludrocortisone,DB00687
,302058,DB00489,10006093,24,1059,34,1100,0.287430682,0.733315318,0.413042751,1.283219605,0.452334409,DB0048910006093_,0.79333353,-0.310179495,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,sotalol,DB00489
,302067,DB00813,10022000,43,10529,32,10136,0.298417157,1.293574902,0.798983702,2.114084301,0.464410597,DB0081310022000_,0.766986212,0.257409627,NA,10022000,Influenza,10021881,Infections and infestations,Infec,fentanyl,DB00813
,302101,DB00635,10056812,44,33009,15,23779,0.01158612,2.113071273,1.153229627,4.088859436,0.040052761,DB0063510056812_,3.217557672,0.748142469,NA,10056812,Body height decreased,10022891,Investigations,Inv,prednisone,DB00635
,302121,DB06262,10037087,33,3767,31,4283,0.453649367,1.210300802,0.717032294,2.047606299,0.621196301,DB0626210037087_,0.476108142,0.190868925,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,droxidopa,DB06262
,302122,DB00853,10039906,71,1750,96,2170,0.633618082,0.917075728,0.660638065,1.268227185,0.77213896,DB0085310039906_,0.258590746,-0.086565228,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,temozolomide,DB00853
,302141,DB00722,10031252,38,25365,44,25988,0.658675083,0.884851018,0.557641188,1.398165224,0.791554443,DB0072210031252_,0.233756618,-0.122335989,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,lisinopril,DB00722
,302163,DB00869,10020751,43,1262,28,901,0.806873389,1.096397495,0.660030954,1.847469956,0.895655188,DB0086910020751_,0.110199775,0.092029801,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,dorzolamide,DB00869
,302170,DB00281,10013710,82,11376,67,5604,0.002822054,0.602907726,0.430554997,0.846895709,0.012856867,DB0028110013710_,4.35387725,-0.505991119,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,302171,DB00668,10013710,36,10055,39,4264,6.63591351624782e-05,0.391474533,0.241464614,0.633142554,0.000560672,DB0066810013710_,7.486374909,-0.937834817,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,302174,DB00211,10020772,49,1387,35,1596,0.035113234,1.610690139,1.01609707,2.577158719,0.095642628,DB0021110020772_,2.347136661,0.476662745,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,midodrine,DB00211
,302282,DB00211,10010305,25,1411,58,1573,0.002410664,0.480632695,0.286458872,0.785503954,0.011330231,DB0021110010305_,4.480280858,-0.732651929,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,midodrine,DB00211
,302406,DB00112,10018884,40,5893,15,4076,0.053072783,1.844337515,0.995248478,3.599405047,0.130766601,DB0011210018884_,2.034341213,0.612120143,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,bevacizumab,DB00112
,302451,DB01076,10016970,42,25705,18,25565,0.00266325,2.320732866,1.306776201,4.283852471,0.012268405,DB0107610016970_,4.400728044,0.841883026,NA,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,302472,DB00695,10061599,54,27995,17,20511,0.001627921,2.327232557,1.328104838,4.283342682,0.008212243,DB0069510061599_,4.802129164,0.844679818,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,302475,DB01076,10061599,36,25711,17,25566,0.012638782,2.105664405,1.152207288,3.998932025,0.04291292,DB0107610061599_,3.148582326,0.744631049,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,302528,DB00868,10002855,47,2937,17,1629,0.148473248,1.53330517,0.860913411,2.858149781,0.28188951,DB0086810002855_,1.266240092,0.427425647,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,benzonatate,DB00868
,302533,DB00514,10013709,127,2039,68,1468,0.061705372,1.344526494,0.985691246,1.84707832,0.146568381,DB0051410013709_,1.920263192,0.296041902,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dextromethorphan,DB00514
,302555,DB00868,10040753,59,2925,14,1632,0.002877421,2.350981341,1.29184177,4.574353368,0.01306608,DB0086810040753_,4.337735687,0.854832833,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,benzonatate,DB00868
,302587,DB00115,10033664,40,18385,10,10462,0.017805755,2.276143927,1.117978369,5.106614423,0.056398658,DB0011510033664_,2.875309923,0.822482751,NA,10033664,Panic attack,10037175,Psychiatric disorders,Psych,cyanocobalamin,DB00115
,302588,DB00169,10033664,70,38621,11,18164,0.000188434,2.992860389,1.573923767,6.27025494,0.001371291,DB0016910033664_,6.592002572,1.096229582,female,10033664,Panic attack,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,302619,DB00537,10048959,109,7448,41,4257,0.025909076,1.519470014,1.049737428,2.236908328,0.075494058,DB0053710048959_,2.583701322,0.418361599,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,302631,DB13961,10019303,48,9409,22,6392,0.143068232,1.482181016,0.876566251,2.581117216,0.274143086,DB1396110019303_,1.294105099,0.393514662,NA,10019303,Heart rate increased,10022891,Investigations,Inv,fish oil,DB13961
,302639,DB01115,10003549,126,3474,48,2220,0.002572422,1.677320494,1.188403837,2.400866286,0.011931554,DB0111510003549_,4.428568778,0.517197576,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,302689,DB01050,10057362,49,18059,26,9345,0.903490542,0.975215704,0.593907022,1.63592099,0.957397657,DB0105010057362_,0.043536449,-0.025096597,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,302735,DB00008,10001760,66,1459,17,1659,2.15713165862913e-09,4.413165879,2.544899631,8.063327704,5.6000203108214e-08,DB0000810001760_,16.69791052,1.484592318,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,peginterferon alfa-2a,DB00008
,302796,DB00008,10038153,33,1492,23,1653,0.104899218,1.589364269,0.900843504,2.848758876,0.218363503,DB0000810038153_,1.521594159,0.463334106,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,peginterferon alfa-2a,DB00008
,302826,DB00996,10054786,38,38915,23,22402,0.894367088,0.951105123,0.552089547,1.672671312,0.955931269,DB0099610054786_,0.045069263,-0.050130683,NA,10054786,Skin burning sensation,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,302855,DB00207,10023547,31,9049,22,5433,0.571216752,0.846031279,0.473768241,1.535231208,0.721500832,DB0020710023547_,0.326421747,-0.167198947,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,azithromycin,DB00207
,302862,DB00678,10023547,70,15529,40,10684,0.38215999,1.203977992,0.80437226,1.824231718,0.552230639,DB0067810023547_,0.593789495,0.185631067,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,losartan,DB00678
,302915,DB01068,10026749,36,13727,27,6813,0.108781289,0.66175892,0.390352125,1.134397843,0.224198548,DB0106810026749_,1.495223246,-0.412853959,NA,10026749,Mania,10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,302923,DB08877,10028810,50,3239,47,3182,0.838683589,1.045115356,0.685407915,1.595853392,0.917178281,DB0887710028810_,0.086453408,0.044127267,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ruxolitinib,DB08877
,303011,DB06186,10042772,19,2190,36,3610,0.676863511,0.869987744,0.47014093,1.561967422,0.804020128,DB0618610042772_,0.218130976,-0.139276155,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,ipilimumab,DB06186
,303028,DB01281,10028334,55,8877,6,1792,0.170282876,1.850377196,0.796279648,5.267095631,0.311225213,DB0128110028334_,1.167238472,0.615389508,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,abatacept,DB01281
,303050,DB01234,10019063,47,31578,51,32837,0.840576854,0.958300708,0.630589606,1.453629858,0.91854006,DB0123410019063_,0.084969761,-0.042593659,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,303084,DB00950,10015150,60,4658,10,2046,0.002456621,2.635164281,1.334958268,5.785572867,0.011507134,DB0095010015150_,4.464788092,0.968945526,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,fexofenadine,DB00950
,303119,DB00073,10071066,59,7347,29,6378,0.013249614,1.766078168,1.112604912,2.861259791,0.044540564,DB0007310071066_,3.11135496,0.568761364,NA,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,rituximab,DB00073
,303125,DB00563,10040808,65,46581,27,15321,0.333054784,0.791824794,0.498161718,1.290954829,0.502070083,DB0056310040808_,0.689015561,-0.233415131,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,methotrexate,DB00563
,303164,DB00921,10013710,33,5812,58,4845,0.000640435,0.474329744,0.299127276,0.740977756,0.003805114,DB0092110013710_,5.571409452,-0.745852536,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,303288,DB00656,10031161,45,11968,11,6608,0.011719858,2.258663033,1.149192977,4.846387575,0.040398198,DB0065610031161_,3.2089701,0.81477306,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,303370,DB01222,10019974,48,9226,15,5390,0.035648316,1.869425277,1.027894198,3.598070319,0.096774178,DB0122210019974_,2.335375079,0.625631045,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,budesonide,DB01222
,303425,DB14500,10070863,42,7767,13,4060,0.116639771,1.688733628,0.888021466,3.432782266,0.236090897,DB1450010070863_,1.443538391,0.523978916,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium,DB14500
,303429,DB08904,10012378,93,11517,17,3542,0.05407007,1.682352438,0.994612976,3.014904897,0.132608518,DB0890410012378_,2.020353963,0.520193075,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,certolizumab pegol,DB08904
,303436,DB08904,10047899,114,11496,19,3540,0.010141862,1.847461113,1.128523741,3.18608651,0.035973127,DB0890410047899_,3.324983099,0.613812325,NA,10047899,Weight increased,10022891,Investigations,Inv,certolizumab pegol,DB08904
,303492,DB00455,10038153,51,9350,18,5100,0.129357917,1.54541116,0.886545508,2.813934892,0.254704135,DB0045510038153_,1.367652661,0.435289998,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,loratadine,DB00455
,303527,DB00877,10011906,25,1083,58,1373,0.012957423,0.546582916,0.32534173,0.894536451,0.043765253,DB0087710011906_,3.128915077,-0.604069262,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sirolimus,DB00877
,303635,DB00620,10006451,65,4763,7,3125,3.12922340597366e-08,6.090630772,2.789871966,15.76702126,6.30522324461616e-07,DB0062010006451_,14.27671727,1.806751651,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,triamcinolone,DB00620
,303653,DB00620,10069339,42,4786,69,3063,1.14887908671178e-06,0.389605968,0.258217612,0.581689817,1.61834334374164e-05,DB0062010069339_,11.03152247,-0.94261939,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,triamcinolone,DB00620
,303676,DB00653,10053762,48,1044,44,778,0.333776497,0.813050994,0.522796891,1.267081686,0.502869643,DB0065310053762_,0.687424302,-0.206961448,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium sulfate,DB00653
,303689,DB01098,10013971,23,8126,33,7176,0.081195428,0.615513561,0.344746058,1.081539079,0.180407593,DB0109810013971_,1.712536581,-0.4852983,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,303739,DB00471,10040829,48,14141,10,5455,0.078427622,1.851616874,0.924144988,4.107700429,0.175735905,DB0047110040829_,1.73877295,0.616059243,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,montelukast,DB00471
,303750,DB08895,10040943,49,28065,9,6637,0.616048181,1.287527378,0.625448733,2.982628803,0.757259402,DB0889510040943_,0.278049413,0.252723618,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,303781,DB00152,10016256,42,789,49,815,0.591501681,0.885452336,0.565097197,1.382242297,0.737822975,DB0015210016256_,0.304051354,-0.121656651,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,thiamine,DB00152
,303790,DB01240,10040070,39,5712,11,1565,0.864492253,0.971401811,0.486484934,2.1081571,0.937874163,DB0124010040070_,0.064139494,-0.029015085,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,303833,DB01432,10013968,47,1244,21,649,0.604818725,1.167558807,0.677508116,2.074998327,0.748052492,DB0143210013968_,0.290282127,0.15491508,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholestyramine,DB01432
,303847,DB00836,10016766,40,5495,26,4049,0.708070794,1.133568977,0.673720071,1.938152996,0.825584719,DB0083610016766_,0.191663393,0.125371042,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,303860,DB00836,10035598,49,5486,39,4036,0.745669076,0.924337653,0.593325782,1.448695265,0.85479359,DB0083610035598_,0.156895254,-0.078677849,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loperamide,DB00836
,303884,DB00904,10038776,63,23006,20,14436,0.006534134,1.976551623,1.178549729,3.452949215,0.025343397,DB0090410038776_,3.675237054,0.681353722,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,303949,DB00999,10041232,40,21390,12,12227,0.059530317,1.905372798,0.979529004,3.991456215,0.142613414,DB0099910041232_,1.947617711,0.644677684,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrochlorothiazide,DB00999
,303951,DB00695,10043417,47,28002,37,20491,0.741466592,0.929546441,0.591143677,1.471458888,0.851737146,DB0069510043417_,0.160477314,-0.07305851,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,303954,DB00999,10043417,60,21370,26,12213,0.262642363,1.318840534,0.819075749,2.178629091,0.42440841,DB0099910043417_,0.857059056,0.276752967,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,304041,DB00153,10039906,53,7370,33,3406,0.200155887,0.742230225,0.470774981,1.185890388,0.349180161,DB0015310039906_,1.052167269,-0.298095808,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,ergocalciferol,DB00153
,304052,DB00153,10047943,36,7387,15,3424,0.880159417,1.112426484,0.593101865,2.189934661,0.949694712,DB0015310047943_,0.051614701,0.106543651,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,ergocalciferol,DB00153
,304130,DB00480,10013395,49,67379,81,67581,0.006313798,0.6067577,0.416542477,0.875856176,0.024666793,DB0048010013395_,3.702297349,-0.499625744,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,304161,DB01281,10031161,53,8879,12,1786,0.738397885,0.888389295,0.467508836,1.83044993,0.849356322,DB0128110031161_,0.163276485,-0.118345237,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,abatacept,DB01281
,304162,DB00563,10031264,31,46615,20,15328,0.022262996,0.509652476,0.281306122,0.943812126,0.067217791,DB0056310031264_,2.699817321,-0.674026205,NA,10031264,Osteonecrosis,10028395,Musculoskeletal and connective tissue disorders,Musc,methotrexate,DB00563
,304205,DB00996,10014551,44,38909,9,22416,0.002492522,2.816504287,1.356663152,6.562661356,0.011630737,DB0099610014551_,4.454103907,1.035496502,female,10014551,Emotional disorder,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,304227,DB01275,10011224,64,3915,38,3311,0.089335457,1.424302824,0.9361341,2.193467855,0.194185031,DB0127510011224_,1.638943805,0.353682448,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydralazine,DB01275
,304254,DB01377,10053762,99,3697,72,2598,0.874970736,0.966242991,0.702963328,1.333569245,0.946077394,DB0137710053762_,0.055430902,-0.034339933,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium oxide,DB01377
,304368,DB05679,10020751,55,6876,30,4879,0.270197379,1.300848526,0.817791255,2.10602102,0.432846057,DB0567910020751_,0.837373141,0.263016764,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ustekinumab,DB05679
,304495,DB00722,10047302,40,25363,59,25973,0.086762973,0.694279526,0.452574902,1.055260227,0.189651955,DB0072210047302_,1.662564703,-0.364880624,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,lisinopril,DB00722
,304562,DB00798,10069339,56,751,50,594,0.611884274,0.88593453,0.584630207,1.345515144,0.753852039,DB0079810069339_,0.282559165,-0.121112225,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,gentamicin,DB00798
,304608,DB00115,10022972,37,18388,16,10456,0.393858486,1.314950331,0.713294941,2.533280429,0.563819421,DB0011510022972_,0.573021254,0.273798894,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,cyanocobalamin,DB00115
,304630,DB00537,10001760,59,7498,7,4291,3.8487283500423e-06,4.822683826,2.197607837,12.52787148,4.69546645072462e-05,DB0053710001760_,9.966328007,1.573330584,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,ciprofloxacin,DB00537
,304669,DB01015,10076309,59,9828,51,9330,0.633950468,1.098216072,0.741307591,1.631963339,0.772364311,DB0101510076309_,0.258298935,0.093687111,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sulfamethoxazole,DB01015
,304702,DB14512,10047899,60,4784,24,2388,0.415296137,1.247833972,0.763306506,2.100790963,0.584550584,DB1451210047899_,0.53691196,0.221409226,NA,10047899,Weight increased,10022891,Investigations,Inv,mometasone furoate,DB14512
,304734,DB08895,10003658,72,28042,32,6614,0.003908392,0.530714787,0.345061082,0.832688002,0.016747977,DB0889510003658_,4.089477779,-0.633530527,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,tofacitinib,DB08895
,304758,DB08895,10013911,45,28069,6,6640,0.214305566,1.774155958,0.75412971,5.091034909,0.366649644,DB0889510013911_,1.003348535,0.573324793,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,304803,DB00661,10047895,49,3479,20,1575,0.793851343,1.109129691,0.644705319,1.976837932,0.888291402,DB0066110047895_,0.118455435,0.103575646,NA,10047895,Weight decreased,10022891,Investigations,Inv,verapamil,DB00661
,304809,DB01281,10047899,86,8846,7,1791,0.016713522,2.487280959,1.154061465,6.382269638,0.053663339,DB0128110047899_,2.925025203,0.91119013,NA,10047899,Weight increased,10022891,Investigations,Inv,abatacept,DB01281
,304859,DB00555,10014387,71,6976,27,3459,0.280874668,1.303893689,0.824618958,2.117178131,0.444773219,DB0055510014387_,0.810190748,0.265354933,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,lamotrigine,DB00555
,304885,DB00555,10054889,29,7018,30,3456,0.005163012,0.476058615,0.275211409,0.822327205,0.020986589,DB0055510054889_,3.863871652,-0.742214292,NA,10054889,Transaminases increased,10022891,Investigations,Inv,lamotrigine,DB00555
,304898,DB01222,10022061,57,9217,8,5397,1.39339467230731e-05,4.171723894,1.978533094,10.13388208,0.000145397,DB0122210022061_,8.836046048,1.428329354,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,304951,DB00175,10037162,39,8092,13,6093,0.010822909,2.258753124,1.17907739,4.615736013,0.037923104,DB0017510037162_,3.272194746,0.814812946,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,pravastatin,DB00175
,304952,DB00335,10037162,55,8411,20,5445,0.032072481,1.780186564,1.048686104,3.139712014,0.089270416,DB0033510037162_,2.416085134,0.57671817,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,304980,DB00087,10046571,58,1311,19,728,0.051717402,1.694741365,0.985517676,3.038304812,0.128274267,DB0008710046571_,2.053584595,0.527530142,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,alemtuzumab,DB00087
,304998,DB00737,10013709,102,2699,24,908,0.142086081,1.429622054,0.902668189,2.348113289,0.272717707,DB0073710013709_,1.299318059,0.357410112,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,meclizine,DB00737
,305002,DB00285,10065154,65,10886,11,3707,0.033358018,2.012244148,1.052265017,4.233063297,0.09205828,DB0028510065154_,2.385333429,0.699250591,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,venlafaxine,DB00285
,305003,DB00295,10065154,36,14627,21,9581,0.786501373,1.122915246,0.637630384,2.025721071,0.88416862,DB0029510065154_,0.123107488,0.115928202,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,morphine,DB00295
,305004,DB00316,10065154,309,65165,146,36807,0.078245004,1.195389955,0.978248473,1.466285677,0.17542391,DB0031610065154_,1.740549891,0.178472454,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,305005,DB00451,10065154,293,46978,86,15333,0.402963303,1.111989469,0.870931763,1.432182251,0.572716115,DB0045110065154_,0.557365121,0.106150725,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,levothyroxine,DB00451
,305010,DB01101,10065154,182,7407,100,3808,0.610813843,0.935683508,0.726688236,1.210412167,0.752932427,DB0110110065154_,0.283779794,-0.066477992,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,capecitabine,DB01101
,305042,DB09027,10022004,48,5131,51,7101,0.21970386,1.302490532,0.858112731,1.974276164,0.373092205,DB0902710022004_,0.985929691,0.264278225,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,305068,DB00996,10040026,41,38912,29,22396,0.387931352,0.813729604,0.493430583,1.358112602,0.55799363,DB0099610040026_,0.583407732,-0.20612715,NA,10040026,Sensory disturbance,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,305148,DB00758,10020100,34,8266,35,10039,0.545069871,1.179779784,0.713206101,1.949693783,0.699927284,DB0075810020100_,0.356778829,0.165327797,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,305156,DB01261,10035528,26,3755,30,3273,0.346776166,0.755453775,0.428193232,1.324618088,0.516182661,DB0126110035528_,0.661294581,-0.280436683,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,sitagliptin,DB01261
,305161,DB05676,10061024,90,47039,59,25270,0.263420016,0.819493625,0.583437348,1.158513665,0.425228049,DB0567610061024_,0.855129668,-0.19906866,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,apremilast,DB05676
,305168,DB00761,10062237,76,15231,62,8563,0.032684826,0.689198539,0.485717373,0.981001512,0.090591902,DB0076110062237_,2.40139045,-0.372225895,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,potassium chloride,DB00761
,305178,DB00321,10010144,684,6763,248,2602,0.465843173,1.061132379,0.909684377,1.240696506,0.632653275,DB0032110010144_,0.457832756,0.05933662,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,amitriptyline,DB00321
,305196,DB00273,10029331,45,8436,19,2174,0.086050415,0.610387737,0.349026084,1.107408257,0.188437792,DB0027310029331_,1.668987342,-0.49366089,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,305217,DB05676,10001949,36,47093,18,25311,0.886936833,1.074941694,0.594509509,2.011282281,0.952995734,DB0567610001949_,0.048144852,0.072266422,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,305222,DB00316,10003053,40,65434,13,36940,0.086724954,1.737031245,0.909980198,3.540140852,0.189584615,DB0031610003053_,1.662919835,0.552177475,NA,10003053,Application site pruritus,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,305276,DB08906,10016173,65,2128,31,1127,0.664884041,1.110441418,0.70855366,1.77381921,0.796043285,DB0890610016173_,0.228101716,0.10475761,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone furoate,DB08906
,305324,DB00480,10036653,56,67372,37,67625,0.049011427,1.519184171,0.985191375,2.367739105,0.12313758,DB0048010036653_,2.094453014,0.418173461,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,305343,DB05676,10047461,64,47065,19,25310,0.02107062,1.81141101,1.071223346,3.202712079,0.064426366,DB0567610047461_,2.742232322,0.594106105,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,apremilast,DB05676
,305399,DB00526,10061428,27,1571,53,1841,0.030989161,0.597074685,0.359246254,0.971666352,0.086903882,DB0052610061428_,2.442952578,-0.515713074,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,oxaliplatin,DB00526
,305425,DB13867,10061428,76,4474,47,2507,0.635738613,0.906110664,0.619488215,1.337370517,0.773593327,DB1386710061428_,0.256708961,-0.098593835,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,fluticasone,DB13867
,305447,DB00207,10071404,28,9052,41,5414,0.000251866,0.408482066,0.24296462,0.677597884,0.001746781,DB0020710071404_,6.349980888,-0.895307267,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,azithromycin,DB00207
,305462,DB01069,10042458,43,6657,9,2386,0.156750375,1.712438148,0.821751122,4.001063564,0.293105471,DB0106910042458_,1.227222766,0.537918173,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,promethazine,DB01069
,305675,DB06637,10022086,46,6116,13,2006,0.762066736,1.160564585,0.614988863,2.346511168,0.868191927,DB0663710022086_,0.141342474,0.148906598,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,305690,DB00722,10003285,110,25293,65,25967,0.000355796,1.737373265,1.266485794,2.400040397,0.002325524,DB0072210003285_,6.063810012,0.552374355,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,305705,DB00230,10031282,63,19611,10,8641,0.001291496,2.775793229,1.41347703,6.071824769,0.006789395,DB0023010031282_,4.99239347,1.020936554,female,10031282,Osteoporosis,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,305730,DB00471,10010144,58,14131,32,5433,0.124396002,0.696872746,0.444504963,1.110352854,0.247680105,DB0047110010144_,1.395617266,-0.361152459,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,montelukast,DB00471
,305733,DB00471,10070863,53,14136,16,5449,0.42297687,1.276834697,0.718050671,2.395116026,0.591883891,DB0047110070863_,0.524444793,0.244384122,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,305737,DB06285,10046571,130,8720,9,1097,0.100877863,1.817062222,0.924565509,4.074896878,0.212126425,DB0628510046571_,1.550572836,0.597221033,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,teriparatide,DB06285
,305818,DB00230,10058319,40,19634,17,8634,1,1.034666415,0.573082297,1.947594343,1,DB0023010058319_,0,0.03407907,NA,10058319,Dysgraphia,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,305894,DB00575,10022000,33,5211,26,3803,0.79240046,0.926295938,0.536293363,1.615644224,0.887531177,DB0057510022000_,0.119311629,-0.076561508,NA,10022000,Influenza,10021881,Infections and infestations,Infec,clonidine,DB00575
,305929,DB01075,10043417,37,19911,13,11084,0.183647313,1.584366706,0.822688086,3.249929931,0.328501794,DB0107510043417_,1.113212979,0.460184773,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,305937,DB09072,10061623,52,6419,18,2517,0.78962019,1.132764445,0.650306587,2.061849627,0.886026326,DB0907210061623_,0.121008615,0.124661056,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,305969,DB00009,10033371,39,1312,59,1492,0.181656459,0.751779757,0.484913768,1.154228255,0.326005531,DB0000910033371_,1.12084093,-0.285311875,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,alteplase,DB00009
,306053,DB08904,10007882,65,11545,33,3526,0.022394085,0.601595353,0.389150066,0.946073404,0.067497106,DB0890410007882_,2.695670557,-0.508170231,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,306055,DB08904,10019974,118,11492,30,3529,0.381993593,1.207842085,0.801658784,1.872136003,0.552126782,DB0890410019974_,0.593977582,0.188835367,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,306163,DB00186,10019196,37,16864,26,9982,0.515735684,0.842348342,0.496177665,1.449698533,0.67545354,DB0018610019196_,0.392370903,-0.171561642,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,306173,DB00904,10029223,51,23018,24,14432,0.285384185,1.332338603,0.804768257,2.264379869,0.449989401,DB0090410029223_,0.798531251,0.286935746,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,306176,DB00182,10039906,71,5123,54,2798,0.073404881,0.718163174,0.495435238,1.046144242,0.16718923,DB0018210039906_,1.788628996,-0.331058474,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,amphetamine,DB00182
,306191,DB01069,10049848,41,6659,14,2381,1,1.047110788,0.558004884,2.083779844,1,DB0106910049848_,0,0.046034741,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,promethazine,DB01069
,306286,DB00572,10053762,103,2799,110,2016,0.00560774,0.674490028,0.507254301,0.896294424,0.022426695,DB0057210053762_,3.79750329,-0.393798388,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,atropine,DB00572
,306311,DB05676,10029216,82,47047,28,25301,0.035896371,1.574921598,1.014098276,2.513596866,0.09732193,DB0567610029216_,2.329730929,0.454205492,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,306320,DB00126,10023547,43,10128,43,5902,0.013493037,0.582789038,0.372368529,0.912045976,0.045191701,DB0012610023547_,3.096841808,-0.539930013,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,ascorbic acid,DB00126
,306323,DB00437,10023547,34,6887,60,11486,0.831531037,0.945073288,0.600874454,1.464730182,0.911972683,DB0043710023547_,0.092145242,-0.056492801,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,allopurinol,DB00437
,306327,DB01136,10023547,25,9859,45,11070,0.071285437,0.623811329,0.366294005,1.040131178,0.163502418,DB0113610023547_,1.810927498,-0.471907314,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,carvedilol,DB01136
,306341,DB00297,10039906,46,1626,16,863,0.175984418,1.525671727,0.84184567,2.904994482,0.318645949,DB0029710039906_,1.143674671,0.42243479,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,bupivacaine,DB00297
,306347,DB00158,10013781,101,16714,25,8079,0.002145443,1.952757323,1.249121758,3.161464414,0.010306674,DB0015810013781_,4.574963604,0.669242386,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,folic acid,DB00158
,306362,DB00158,10040829,72,16743,24,8080,0.126735874,1.447749121,0.900288905,2.405408952,0.251083659,DB0015810040829_,1.381969091,0.37001002,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,folic acid,DB00158
,306387,DB00169,10012671,51,38640,22,18153,0.802505436,1.08907396,0.648521424,1.886377724,0.893182961,DB0016910012671_,0.112963836,0.085327757,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,cholecalciferol,DB00169
,306389,DB00722,10012671,82,25321,85,25947,1,0.988555165,0.720484838,1.355733297,1,DB0072210012671_,0,-0.011510831,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,lisinopril,DB00722
,306474,DB00641,10054236,52,14072,30,12445,0.075587143,1.532897023,0.959206789,2.490372568,0.170761328,DB0064110054236_,1.767488438,0.427159424,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,simvastatin,DB00641
,306497,DB00203,10040943,41,13837,18,8920,0.184079003,1.468341572,0.824310436,2.717188972,0.329027683,DB0020310040943_,1.111613389,0.384133581,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,sildenafil,DB00203
,306514,DB01234,10048962,25,31600,37,32851,0.203596619,0.702431199,0.405214455,1.198831478,0.353409193,DB0123410048962_,1.040128707,-0.35320782,NA,10048962,Brain oedema,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,306633,DB01373,10015946,40,22680,11,7370,0.745175424,1.181648209,0.594633672,2.554711337,0.854485157,DB0137310015946_,0.157256147,0.166910251,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,calcium,DB01373
,306645,DB00091,10033775,45,5465,8,2662,0.004995747,2.739662287,1.275763303,6.739115039,0.020456957,DB0009110033775_,3.889432268,1.00783466,female,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,cyclosporine,DB00091
,306670,DB00996,10038683,53,38900,27,22398,0.64373636,1.130259881,0.698084855,1.869435697,0.780052855,DB0099610038683_,0.248393598,0.122447589,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,306754,DB01050,10047340,64,18044,19,9352,0.03617149,1.745781807,1.031933524,3.087884206,0.097886093,DB0105010047340_,2.323950795,0.557202482,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,ibuprofen,DB01050
,306761,DB00108,10005169,42,10152,18,3277,0.296044467,0.753202015,0.423598277,1.392201841,0.461894035,DB0010810005169_,0.772419776,-0.283421806,NA,10005169,Blindness,10015919,Eye disorders,Eye,natalizumab,DB00108
,306780,DB08906,10002855,46,2147,9,1149,0.00385889,2.734610675,1.316431981,6.377652615,0.016563788,DB0890610002855_,4.10053641,1.005989077,female,10002855,Anxiety,10037175,Psychiatric disorders,Psych,fluticasone furoate,DB08906
,306781,DB00215,10017944,47,11056,12,5264,0.051314937,1.864746745,0.972969166,3.865262695,0.127476199,DB0021510017944_,2.059825609,0.623125251,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,citalopram,DB00215
,306802,DB00654,10041349,33,3783,19,2579,0.670848222,1.184006858,0.652186484,2.209137163,0.800335284,DB0065410041349_,0.222724534,0.168904329,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,latanoprost,DB00654
,306904,DB00722,10048302,28,25375,33,25999,0.610347829,0.869353002,0.505961638,1.484081202,0.752503233,DB0072210048302_,0.284349985,-0.14000602,NA,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,306984,DB01104,10042128,56,15407,27,7259,0.906652603,0.977181939,0.60638861,1.610542296,0.958352985,DB0110410042128_,0.042539109,-0.023082422,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,306996,DB00843,10012239,16,2178,46,2127,9.83871941650348e-05,0.339751194,0.178938839,0.613700517,0.000785693,DB0084310012239_,7.148944857,-1.079541712,male,10012239,Delusion,10037175,Psychiatric disorders,Psych,donepezil,DB00843
,307014,DB00190,10057668,28,3269,47,4627,0.556168094,0.843258893,0.507354138,1.377988491,0.709596813,DB0019010057668_,0.343058339,-0.170481259,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,307103,DB00343,10015150,66,8670,22,5073,0.020033053,1.755296547,1.067685705,2.991382616,0.061843772,DB0034310015150_,2.78314388,0.562637815,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,diltiazem,DB00343
,307132,DB00820,10013952,76,11839,18,5798,0.004025505,2.067706026,1.223303605,3.67749115,0.017171437,DB0082010013952_,4.064507913,0.726439793,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,307196,DB01285,10016256,93,1183,30,579,0.057892233,1.516931579,0.982218774,2.401389088,0.139509268,DB0128510016256_,1.96962424,0.416689596,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,corticotropin,DB01285
,307281,DB00186,10007739,41,16860,18,9990,0.345518255,1.349629581,0.757734943,2.497175402,0.514937196,DB0018610007739_,0.663710336,0.29983017,NA,10007739,Cataract,10015919,Eye disorders,Eye,lorazepam,DB00186
,307338,DB00338,10028997,49,33625,50,22222,0.031167179,0.6476833,0.427535223,0.980631161,0.087277398,DB0033810028997_,2.438663751,-0.434353437,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,omeprazole,DB00338
,307346,DB00950,10043607,30,4688,24,2032,0.036152352,0.541893144,0.305407024,0.971130192,0.097844376,DB0095010043607_,2.324377067,-0.612686448,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,fexofenadine,DB00950
,307451,DB00555,10000087,51,6996,10,3476,0.005810027,2.533774317,1.269981723,5.604547577,0.023072451,DB0055510000087_,3.769115971,0.929710016,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,lamotrigine,DB00555
,307621,DB00182,10040753,70,5124,10,2842,5.16752906812377e-06,3.88201714,1.986695288,8.461528697,6.09643184720078e-05,DB0018210040753_,9.705221808,1.3563549,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,amphetamine,DB00182
,307689,DB00327,10040753,45,6093,7,4255,2.55183027988229e-05,4.488827044,2.006896564,11.80921998,0.000245831,DB0032710040753_,8.31086818,1.50159143,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,hydromorphone,DB00327
,307703,DB00668,10006482,33,10058,29,4274,0.005130521,0.483560111,0.284280058,0.826702366,0.020881965,DB0066810006482_,3.868869392,-0.726579647,NA,10006482,Bronchospasm,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epinephrine,DB00668
,307714,DB00451,10018867,74,47197,54,15365,1.23269559236304e-05,0.446125526,0.309755229,0.646157389,0.000130362,DB0045110018867_,8.945197567,-0.807154919,NA,10018867,Haematuria,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,307739,DB00338,10054786,52,33622,17,22255,0.009592137,2.02465902,1.151663844,3.735579676,0.034441545,DB0033810054786_,3.368491743,0.705401301,NA,10054786,Skin burning sensation,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,307742,DB01592,10008479,96,6180,35,3032,0.159508444,1.345672957,0.902632118,2.047615407,0.296795346,DB0159210008479_,1.214712448,0.296894228,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,307805,DB00273,10074903,68,8413,21,2172,0.509496731,0.835993724,0.504800398,1.439475325,0.670075131,DB0027310074903_,0.400365437,-0.179134173,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,topiramate,DB00273
,307846,DB00285,10067482,40,10911,14,3704,0.876591395,0.969925979,0.515883154,1.932283536,0.947301106,DB0028510067482_,0.054138278,-0.03053552,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,307955,DB00761,10029366,69,15238,32,8593,0.406528314,1.215900985,0.787924028,1.913068749,0.576138414,DB0076110029366_,0.551407344,0.195485353,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,308000,DB00321,10006451,66,7381,19,2831,0.329903865,1.332275586,0.788202808,2.355283257,0.498568412,DB0032110006451_,0.696014463,0.286888447,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,amitriptyline,DB00321
,308001,DB00321,10038669,83,7364,28,2822,0.595675882,1.135943786,0.730420387,1.815411623,0.74122358,DB0032110038669_,0.299452972,0.127463835,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amitriptyline,DB00321
,308002,DB01068,10038669,173,13590,97,6743,0.362451874,0.884938893,0.684968856,1.148796591,0.532145159,DB0106810038669_,0.630838972,-0.122236684,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,308041,DB00363,10069339,17,4611,46,6842,0.038474213,0.548404727,0.294387131,0.976426006,0.102586192,DB0036310069339_,2.277051933,-0.600741711,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,clozapine,DB00363
,308055,DB01211,10025482,39,1613,15,772,0.55698286,1.244247115,0.66577938,2.445288301,0.710211239,DB0121110025482_,0.342192834,0.21853062,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,clarithromycin,DB01211
,308062,DB04854,10013709,18,763,61,1425,0.029542477,0.5512342,0.304270258,0.953428443,0.083708728,DB0485410013709_,2.48041203,-0.595595515,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,febuxostat,DB04854
,308138,DB08932,10005364,109,19334,67,6530,0.000231999,0.549498253,0.401107767,0.757464304,0.00163094,DB0893210005364_,6.418598834,-0.598749685,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,macitentan,DB08932
,308152,DB00820,10028836,121,11794,22,5794,2.64604773690719e-06,2.701840716,1.703432639,4.475922621,3.38861704090648e-05,DB0082010028836_,10.29250358,0.993933288,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,308185,DB00853,10003549,22,1799,62,2204,0.000538844,0.434814003,0.253446766,0.72067967,0.003282389,DB0085310003549_,5.719183835,-0.832836919,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,temozolomide,DB00853
,308221,DB00047,10024264,33,9252,44,8474,0.109977415,0.686951883,0.423337823,1.104887454,0.226025752,DB0004710024264_,1.487106341,-0.375491029,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,insulin glargine,DB00047
,308240,DB06228,10055847,22,15890,38,16038,0.051859033,0.584352777,0.32902421,1.014026626,0.128541154,DB0622810055847_,2.051506158,-0.537250409,NA,10055847,Haemorrhage urinary tract,10038359,Renal and urinary disorders,Renal,rivaroxaban,DB06228
,308249,DB00497,10001488,22,19245,30,16345,0.095722575,0.622844053,0.342186224,1.116980413,0.20435899,DB0049710001488_,1.587877076,-0.473459108,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,308304,DB00373,10020751,83,1749,32,1255,0.002696921,1.860796034,1.215085524,2.9115876,0.012393105,DB0037310020751_,4.390615032,0.621004372,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,timolol,DB00373
,308310,DB00688,10011831,81,6409,116,5262,0.000123795,0.573342827,0.425187223,0.769995586,0.000957469,DB0068810011831_,6.951217544,-0.55627144,NA,10011831,Cytomegalovirus infection,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,308320,DB00688,10054236,36,6454,26,5352,0.611603671,1.148175902,0.673318285,1.983101001,0.753627381,DB0068810054236_,0.282857222,0.138174511,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,308328,DB06282,10033425,45,1495,6,527,0.022045317,2.642654884,1.115169553,7.623417943,0.066737394,DB0628210033425_,2.706989856,0.97178405,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,levocetirizine,DB06282
,308334,DB08904,10053762,702,10908,257,3302,0.013093365,0.826857183,0.711849656,0.962713931,0.044145599,DB0890410053762_,3.120262032,-0.190123291,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,certolizumab pegol,DB08904
,308455,DB00820,10039906,52,11863,31,5785,0.412091168,0.81802122,0.51390902,1.321951177,0.581464764,DB0082010039906_,0.542204903,-0.200867001,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,308456,DB01115,10039906,40,3560,14,2254,0.06703698,1.808818056,0.960798849,3.607799638,0.156031792,DB0111510039906_,1.857695496,0.592673624,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,nifedipine,DB01115
,308457,DB01136,10039906,83,9801,54,11061,0.001887886,1.734572447,1.215276888,2.493767739,0.009283151,DB0113610039906_,4.679554287,0.550760955,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,308467,DB01076,10066152,61,25686,43,25540,0.094884429,1.410525892,0.938855687,2.135820558,0.203023096,DB0107610066152_,1.594435535,0.343962608,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,atorvastatin,DB01076
,308469,DB01136,10066152,40,9844,21,11094,0.004410339,2.146567755,1.234891448,3.834908746,0.018481588,DB0113610066152_,3.990980298,0.763870173,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,carvedilol,DB01136
,308481,DB00471,10001053,46,14143,17,5448,1,1.042296851,0.585699037,1.941216127,1,DB0047110001053_,0,0.041426788,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,montelukast,DB00471
,308553,DB01611,10012601,50,11863,8,2353,0.723233652,1.2396555,0.582116309,3.031892524,0.837250734,DB0161110012601_,0.177631691,0.214833519,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,hydroxychloroquine,DB01611
,308557,DB01611,10013950,62,11851,6,2355,0.100715914,2.053318222,0.890312928,5.816041773,0.211963473,DB0161110013950_,1.551341317,0.719457129,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,308867,DB00374,10062237,49,17667,21,5703,0.26759403,0.75322211,0.442888843,1.323480037,0.429907039,DB0037410062237_,0.844186282,-0.283395128,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,treprostinil,DB00374
,308925,DB00904,10044034,50,23019,39,14417,0.326831605,0.80297411,0.517434999,1.254184939,0.495259353,DB0090410044034_,0.702673707,-0.219432807,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,308978,DB00281,10038669,34,11424,21,5650,0.473137831,0.800767584,0.451082234,1.45332303,0.639125723,DB0028110038669_,0.447654094,-0.222184532,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lidocaine,DB00281
,308979,DB00425,10038669,96,12599,67,7417,0.290713313,0.843521032,0.610188139,1.171873217,0.455998772,DB0042510038669_,0.785265162,-0.170170443,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zolpidem,DB00425
,308992,DB01104,10038743,53,15410,30,7256,0.411837663,0.831880663,0.521408158,1.349823517,0.581309901,DB0110410038743_,0.542471272,-0.184066282,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,309090,DB00863,10042682,59,10614,19,5821,0.043565136,1.702958093,0.999741037,3.028094015,0.112752028,DB0086310042682_,2.182564317,0.532366794,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,309273,DB01261,10039101,31,3750,23,3280,0.586053167,1.178870624,0.663944382,2.121848816,0.733315171,DB0126110039101_,0.310179695,0.164556882,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sitagliptin,DB01261
,309404,DB00787,10047340,36,16964,20,17228,0.031992795,1.827968852,1.029769511,3.334059795,0.089091072,DB0078710047340_,2.418096154,0.603205434,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,acyclovir,DB00787
,309596,DB00635,10013887,49,33004,31,23763,0.650434482,1.138031314,0.71107674,1.84691838,0.785013507,DB0063510013887_,0.242054356,0.129299852,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,309601,DB00688,10036807,31,6459,20,5358,0.401288993,1.285758988,0.708948233,2.383125604,0.57111274,DB0068810036807_,0.560168646,0.251349196,NA,10036807,Progressive multifocal leukoencephalopathy,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,309695,DB00564,10049848,36,2568,23,1440,0.682196313,0.877724973,0.503847645,1.557914406,0.807817551,DB0056410049848_,0.213419049,-0.130421978,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,carbamazepine,DB00564
,309737,DB00656,10062355,66,11947,23,6596,0.059196049,1.584264971,0.971449084,2.671765306,0.141980852,DB0065610062355_,1.952063075,0.460120559,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,309738,DB01060,10062355,49,8538,33,5048,0.568183415,0.877912772,0.552455943,1.411225332,0.719224708,DB0106010062355_,0.329581441,-0.130208038,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,309739,DB01156,10062355,67,13555,30,6298,0.913303127,1.037640464,0.664434436,1.655538771,0.961184788,DB0115610062355_,0.039588601,0.036949351,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,309794,DB00996,10022075,57,38896,19,22406,0.042119813,1.728131459,1.012490699,3.077276253,0.109931416,DB0099610022075_,2.207898596,0.547040743,NA,10022075,Injection site induration,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,309839,DB00999,10053425,83,21347,19,12220,0.000118176,2.500621737,1.504422725,4.362989122,0.000919965,DB0099910053425_,6.991174826,0.916539396,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,309844,DB00009,10055677,45,1306,44,1507,0.451890587,1.180060088,0.755911878,1.843269268,0.619465649,DB0000910055677_,0.478898029,0.16556536,NA,10055677,Haemorrhagic transformation stroke,10029205,Nervous system disorders,Nerv,alteplase,DB00009
,309897,DB00787,10037153,37,16963,17,17231,0.006109384,2.210796707,1.213583129,4.188839426,0.024016324,DB0078710037153_,3.729021516,0.793352952,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,309898,DB00924,10037153,136,10026,39,4212,0.036896296,1.464996138,1.017407159,2.152849467,0.099381989,DB0092410037153_,2.308784379,0.381852607,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,cyclobenzaprine,DB00924
,309939,DB00795,10022095,65,4504,6,1497,0.000748169,3.600287937,1.563131563,10.18994792,0.004325009,DB0079510022095_,5.443341093,1.281013825,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,309954,DB00761,10005734,59,15248,48,8577,0.068752255,0.691445473,0.463899332,1.035043648,0.159066369,DB0076110005734_,1.838433751,-0.368970984,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,309958,DB00480,10005750,212,67216,130,67532,8.23107360254433e-06,1.638419831,1.310523032,2.05480695,9.17336313940546e-05,DB0048010005750_,9.296621491,0.493732259,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,lenalidomide,DB00480
,309970,DB00003,10047700,40,2958,26,2567,0.266178059,1.335031277,0.792388006,2.28526734,0.428312842,DB0000310047700_,0.847901412,0.28895472,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dornase alfa,DB00003
,310037,DB00722,10011781,66,25337,29,26003,8.25816439260438e-05,2.335749666,1.487401205,3.751320265,0.00067759,DB0072210011781_,7.296968658,0.848332896,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,lisinopril,DB00722
,310046,DB00285,10042209,72,10879,13,3705,0.033132961,1.886233388,1.034884024,3.716784451,0.09158209,DB0028510042209_,2.390519546,0.634581924,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,310048,DB00497,10042209,45,19222,29,16346,0.293305266,1.319542705,0.809054322,2.183549659,0.45890053,DB0049710042209_,0.778921802,0.277285241,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,310060,DB00230,10009866,51,19623,18,8633,0.513002558,1.2464727,0.715477277,2.268528879,0.673086193,DB0023010009866_,0.395881885,0.220317722,NA,10009866,Cold sweat,10040785,Skin and subcutaneous tissue disorders,Skin,pregabalin,DB00230
,310066,DB00264,10038743,33,29574,30,24862,0.80078639,0.9247449,0.546567986,1.57008883,0.892288513,DB0026410038743_,0.113965754,-0.078237363,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,310267,DB00497,10073317,33,19234,23,16352,0.504071444,1.219788747,0.694604665,2.176684987,0.665186531,DB0049710073317_,0.40768778,0.198677686,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,310300,DB14513,10046735,72,7105,13,3551,0.000283917,2.76784639,1.518251324,5.454776646,0.001928954,DB1451310046735_,6.250777208,1.018069541,female,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,magnesium,DB14513
,310302,DB08917,10021058,72,844,11,183,0.367067696,1.418795645,0.728904102,3.028700657,0.536678581,DB0891710021058_,0.622355909,0.349808374,NA,10021058,Hypophosphataemia,10027433,Metabolism and nutrition disorders,Metab,ferric carboxymaltose,DB08917
,310376,DB00335,10013911,63,8403,34,5431,0.465274835,1.197539479,0.775879945,1.877328589,0.632077372,DB0033510013911_,0.458743468,0.180269017,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,atenolol,DB00335
,310379,DB01224,10076309,66,8042,46,5871,0.848051148,1.047455314,0.706901162,1.563638717,0.924037741,DB0122410076309_,0.079002363,0.046363712,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,310454,DB01373,10013082,61,22659,13,7368,0.178158493,1.525734798,0.828724052,3.029107308,0.321528099,DB0137310013082_,1.13467034,0.422476129,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,310515,DB00222,10017577,42,3164,36,3092,0.571504812,1.140093751,0.710855571,1.836923581,0.721673944,DB0022210017577_,0.326181843,0.131110497,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,glimepiride,DB00222
,310542,DB00422,10025482,85,3350,39,2910,0.000985006,1.893039756,1.276679716,2.850890358,0.005435262,DB0042210025482_,5.214847501,0.638183873,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,310712,DB00264,10011878,42,29565,42,24850,0.444320601,0.840525665,0.53457865,1.321510635,0.612361944,DB0026410011878_,0.49043176,-0.173727792,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,metoprolol,DB00264
,310728,DB00327,10023232,44,6094,10,4252,0.000711312,3.069719599,1.520036744,6.849340134,0.004147715,DB0032710023232_,5.485197816,1.121586221,female,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,hydromorphone,DB00327
,310748,DB00887,10037844,64,2277,37,1778,0.156192843,1.350565764,0.882691068,2.093084281,0.292364527,DB0088710037844_,1.229753874,0.300523589,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,bumetanide,DB00887
,310816,DB00126,10037884,55,10116,19,5926,0.052717218,1.695698014,0.989610175,3.028825873,0.130134493,DB0012610037884_,2.0391868,0.528094464,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,ascorbic acid,DB00126
,310828,DB06605,10017577,123,13950,94,12939,0.172492435,1.213668761,0.919264337,1.606627875,0.314116923,DB0660510017577_,1.157989997,0.193647806,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,310839,DB00005,10048561,30,128052,30,42389,3.16036417651713e-05,0.33103338,0.192777016,0.56843658,0.000296944,DB0000510048561_,8.121965925,-1.105536061,male,10048561,Stent placement,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,310891,DB00927,10007554,32,7465,27,4989,0.424602235,0.792105088,0.459102845,1.3760931,0.59338436,DB0092710007554_,0.521912927,-0.23306121,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,famotidine,DB00927
,310942,DB00472,10029331,44,10715,29,4283,0.038250495,0.606493913,0.370506597,1.006634567,0.102124353,DB0047210029331_,2.281564063,-0.500060586,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,311003,DB00374,10074300,174,17542,61,5663,0.593265243,0.9208402,0.683034777,1.255840539,0.739331353,DB0037410074300_,0.302009078,-0.082468765,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,treprostinil,DB00374
,311004,DB06403,10074300,73,21398,25,6636,0.635821592,0.905548346,0.567509698,1.49016449,0.773634813,DB0640310074300_,0.256655335,-0.099214612,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,ambrisentan,DB06403
,311074,DB00281,10005734,39,11419,20,5651,0.890426914,0.965035067,0.54875706,1.747976229,0.954638381,DB0028110005734_,0.046422669,-0.03559084,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,lidocaine,DB00281
,311148,DB01202,10051118,50,6664,42,5676,1,1.013976875,0.658182875,1.568968921,1,DB0120210051118_,0,0.013880099,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,311153,DB00601,10070863,36,869,35,876,0.904144558,1.036846666,0.626340344,1.717949915,0.957497529,DB0060110070863_,0.043432138,0.036184055,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,linezolid,DB00601
,311160,DB00869,10022806,37,1268,31,898,0.532964831,0.845341304,0.506071522,1.420635445,0.689723823,DB0086910022806_,0.371464018,-0.168014823,NA,10022806,Intraocular pressure increased,10022891,Investigations,Inv,dorzolamide,DB00869
,311180,DB00544,10018884,20,2415,31,2622,0.259791238,0.700511317,0.377312935,1.272708292,0.421012527,DB0054410018884_,0.86509269,-0.355944758,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,fluorouracil,DB00544
,311221,DB00996,10061148,38,38915,28,22397,0.37061775,0.781103693,0.466760929,1.321807526,0.540334326,DB0099610061148_,0.61556721,-0.247047369,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,311248,DB00787,10041569,44,16956,53,17195,0.417302825,0.841895626,0.551034906,1.280604448,0.586441658,DB0078710041569_,0.533682091,-0.172099232,NA,10041569,Spinal fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,311290,DB00641,10014011,35,14089,18,12457,0.072513808,1.719169802,0.947098746,3.226153402,0.165690916,DB0064110014011_,1.797631179,0.541841501,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,simvastatin,DB00641
,311327,DB00820,10042682,98,11817,15,5801,2.64825635926072e-06,3.207067303,1.850437612,5.952774844,3.39061950332041e-05,DB0082010042682_,10.29191282,1.165356907,female,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,311352,DB00563,10023126,22,46624,31,15317,1.79917400019883e-07,0.233164982,0.128560165,0.416003494,3.08387926933331e-06,DB0056310023126_,12.68932225,-1.456008998,male,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,methotrexate,DB00563
,311366,DB00457,10013968,34,645,16,495,0.143709656,1.630170155,0.863997407,3.201129536,0.275110762,DB0045710013968_,1.290581492,0.488684399,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prazosin,DB00457
,311439,DB00273,10028245,56,8425,9,2184,0.218073399,1.612894111,0.790181271,3.715078512,0.371247363,DB0027310028245_,0.990886692,0.478030149,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,311527,DB00737,10044565,51,2750,13,919,0.466866686,1.310915773,0.698840551,2.63987279,0.633432919,DB0073710044565_,0.456601175,0.270725956,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,meclizine,DB00737
,311595,DB00927,10076309,69,7428,31,4985,0.065529565,1.493712665,0.962837446,2.365222977,0.153372034,DB0092710076309_,1.874888716,0.401264743,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,famotidine,DB00927
,311596,DB01069,10076309,66,6634,22,2373,0.903210784,1.073099594,0.651940277,1.830546402,0.957348417,DB0106910076309_,0.043587882,0.070551278,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,promethazine,DB01069
,311653,DB00695,10050953,57,27992,47,20481,0.552371977,0.887352206,0.592221449,1.335205083,0.706250483,DB0069510050953_,0.347785313,-0.1195133,NA,10050953,Lower gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,furosemide,DB00695
,311685,DB00869,10012735,48,1257,24,905,0.180944157,1.439708117,0.857428998,2.476600059,0.325060122,DB0086910012735_,1.123745123,0.364440397,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dorzolamide,DB00869
,311720,DB00193,10024264,96,19224,45,8657,0.855270262,0.960695055,0.666839761,1.402461246,0.92990731,DB0019310024264_,0.072670364,-0.040098241,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,311736,DB00465,10016256,95,2009,31,852,0.23210033,1.299482613,0.850637663,2.033723273,0.38844718,DB0046510016256_,0.945598078,0.261966195,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ketorolac,DB00465
,311843,DB00678,10070863,96,15503,80,10644,0.218159744,0.823903769,0.605313366,1.123956146,0.371334457,DB0067810070863_,0.990652121,-0.193701541,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,311846,DB00571,10017577,62,5061,25,2584,0.362391948,1.266226535,0.78198588,2.108189986,0.532089842,DB0057110017577_,0.630942928,0.236041245,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,311854,DB00571,10061428,85,5038,37,2572,0.441876846,1.172775628,0.785838915,1.780657073,0.610001465,DB0057110061428_,0.49429392,0.159373271,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,propranolol,DB00571
,311924,DB01394,10020937,33,1407,17,1986,0.000727405,2.739199787,1.475752302,5.266137106,0.00422462,DB0139410020937_,5.466825912,1.007665829,female,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,colchicine,DB01394
,311926,DB00479,10053762,55,560,31,368,0.564806578,1.165702336,0.721706832,1.911737001,0.716495559,DB0047910053762_,0.33338323,0.153323769,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,amikacin,DB00479
,311964,DB09073,10000081,213,20047,13,777,0.112403219,0.63507486,0.361372508,1.217976558,0.229691254,DB0907310000081_,1.471019246,-0.454012397,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,palbociclib,DB09073
,311968,DB09073,10028813,2249,18011,35,755,6.53323491790101e-11,2.693500281,1.91301036,3.907178433,2.2030286057348e-09,DB0907310028813_,19.93343278,0.990841567,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,palbociclib,DB09073
,311972,DB09073,10047700,769,19491,23,767,0.216078173,1.315711725,0.863755067,2.101226278,0.368698418,DB0907310047700_,0.997776266,0.274377755,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,palbociclib,DB09073
,312011,DB09033,10001760,60,2564,12,1657,7.11585454651223e-05,3.230533436,1.713693839,6.619653083,0.000595196,DB0903310001760_,7.426620363,1.172647274,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,vedolizumab,DB09033
,312045,DB01015,10061623,65,9822,61,9320,1,1.011112809,0.701041508,1.460034789,1,DB0101510061623_,0,0.011051516,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,312049,DB00557,10008469,50,5937,12,3055,0.015011319,2.143883785,1.123687663,4.429751163,0.049352411,DB0055710008469_,3.008768659,0.762619037,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,312052,DB00557,10020937,67,5920,17,3050,0.00747423,2.030365334,1.176199372,3.695603733,0.028214868,DB0055710020937_,3.567906218,0.708215744,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,312062,DB00959,10061623,32,8046,31,4971,0.090327519,0.637798391,0.376303455,1.082140785,0.195758653,DB0095910061623_,1.63087274,-0.449733047,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,312067,DB01234,10012434,21,31604,32,32856,0.215730316,0.682254329,0.373820967,1.220509315,0.368296129,DB0123410012434_,0.998867967,-0.382352774,NA,10012434,Dermatitis allergic,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,312074,DB00399,10038153,56,6936,29,4969,0.185014718,1.383369498,0.867040244,2.250442503,0.330163363,DB0039910038153_,1.108167707,0.324522188,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,zoledronic acid,DB00399
,312109,DB11089,10017413,87,10088,72,8335,1,0.998360318,0.721129675,1.385797963,1,DB1108910017413_,0,-0.001641028,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,docusate,DB11089
,312123,DB00316,10002953,47,65427,18,36935,0.195980332,1.474024853,0.839954767,2.697131155,0.344237564,DB0031610002953_,1.066423266,0.387996655,NA,10002953,Aphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,312185,DB01592,10076309,51,6225,26,3041,0.903103338,0.958250121,0.585102473,1.604514033,0.957326661,DB0159210076309_,0.043610607,-0.042646448,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,iron,DB01592
,312190,DB00175,10017413,60,8071,41,6065,0.687112559,1.099712532,0.72596684,1.680489913,0.811307667,DB0017510017413_,0.209107929,0.095048812,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,pravastatin,DB00175
,312194,DB00425,10017413,52,12643,36,7448,0.507122542,0.850936278,0.545197976,1.341273481,0.66773781,DB0042510017413_,0.403859683,-0.161418032,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,zolpidem,DB00425
,312196,DB01015,10017413,54,9833,64,9317,0.231235365,0.799484496,0.545414518,1.168089621,0.38741891,DB0101510017413_,0.948248717,-0.223788139,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,312198,DB08889,10017413,36,3129,21,3864,0.00701127,2.116764954,1.200018926,3.824610096,0.026827459,DB0888910017413_,3.618329337,0.749888958,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,carfilzomib,DB08889
,312203,DB00869,10035664,29,1276,33,896,0.067268643,0.617231906,0.358701361,1.056860634,0.156467085,DB0086910035664_,1.854909612,-0.482510465,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,dorzolamide,DB00869
,312206,DB08889,10047895,40,3125,42,3843,0.503864813,1.171170891,0.738217324,1.855575552,0.664963931,DB0888910047895_,0.408022478,0.15800401,NA,10047895,Weight decreased,10022891,Investigations,Inv,carfilzomib,DB08889
,312239,DB09270,10013709,126,2988,74,2294,0.080746645,1.30716494,0.967936811,1.775633024,0.179585021,DB0927010013709_,1.717106527,0.267860624,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ubidecarenone,DB09270
,312260,DB06605,10042674,124,13949,62,12971,4.74863522864214e-05,1.859725576,1.358940387,2.567624364,0.000422682,DB0660510042674_,7.768891377,0.620428937,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,312277,DB00924,10013654,287,9875,155,4096,0.010902786,0.768015882,0.627283774,0.943146119,0.038144513,DB0092410013654_,3.266373351,-0.263944867,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,312303,DB00635,10066274,29,33024,61,23733,8.8895629167322e-07,0.341663458,0.211599003,0.540139162,1.29237921054373e-05,DB0063510066274_,11.2564406,-1.073929067,male,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,312364,DB00787,10013786,130,16870,83,17165,0.000931992,1.593622139,1.19971968,2.126841991,0.005196735,DB0078710013786_,5.259724653,0.4660095,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,312380,DB00115,10035226,139,18286,168,10304,4.52418055391231e-11,0.466227109,0.369189188,0.588027473,1.56574174930329e-09,DB0011510035226_,20.27490616,-0.763082404,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyanocobalamin,DB00115
,312384,DB08932,10057688,112,19331,28,6569,0.172075192,1.359231307,0.890787416,2.138963715,0.31356348,DB0893210057688_,1.159753452,0.306919324,NA,10057688,Catheter site discharge,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,312404,DB00381,10017413,182,29178,109,22778,0.02847518,1.30347402,1.021755721,1.66943705,0.081328926,DB0038110017413_,2.509253531,0.265033023,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,amlodipine,DB00381
,312453,DB00108,10011968,47,10147,9,3286,0.162459346,1.691042169,0.818174108,3.929241086,0.300607193,DB0010810011968_,1.201950873,0.525345007,NA,10011968,Decreased immune responsiveness,10021428,Immune system disorders,Immun,natalizumab,DB00108
,312489,DB00421,10042609,49,8854,12,5240,0.004860959,2.416475624,1.265285581,4.995845719,0.020005912,DB0042110042609_,3.91172746,0.882310125,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,spironolactone,DB00421
,312545,DB00169,10028034,47,38644,7,18168,0.001931133,3.156525142,1.417475427,8.279212806,0.009462173,DB0016910028034_,4.66045327,1.149471784,female,10028034,Mouth ulceration,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,312597,DB00279,10003239,47,1190,7,209,0.845931622,1.179104426,0.520130655,3.13443749,0.922538514,DB0027910003239_,0.080626154,0.16475519,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,liothyronine,DB00279
,312644,DB00787,10001497,28,16972,40,17208,0.182155803,0.709743615,0.421477345,1.180061702,0.326589495,DB0078710001497_,1.119051265,-0.34285148,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,acyclovir,DB00787
,312796,DB00213,10040984,56,18839,29,13392,0.186239503,1.372692183,0.861246273,2.230891693,0.331738918,DB0021310040984_,1.103407012,0.316773908,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,312859,DB01611,10021015,86,11827,10,2351,0.128191065,1.709466967,0.884333312,3.697149953,0.253098636,DB0161110021015_,1.373976002,0.536181607,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,hydroxychloroquine,DB01611
,312942,DB09037,10061818,21,2505,32,2803,0.333179455,0.734362228,0.401342214,1.317317622,0.502229217,DB0903710061818_,0.688698655,-0.308752874,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,pembrolizumab,DB09037
,313040,DB00364,10040047,46,2704,28,1372,0.458238801,0.833629684,0.507569514,1.391551235,0.625606757,DB0036410040047_,0.46903329,-0.181966,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,sucralfate,DB00364
,313151,DB04861,10033371,69,1896,27,1360,0.00828506,1.832780212,1.151940378,2.99209737,0.030620473,DB0486110033371_,3.486086443,0.605834055,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,nebivolol,DB04861
,313227,DB08932,10028740,59,19384,11,6586,0.072904047,1.822238617,0.94743229,3.849761719,0.166372885,DB0893210028740_,1.793523716,0.600065755,NA,10028740,Nasal dryness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,313247,DB00887,10000059,38,2303,19,1796,0.138654934,1.559541665,0.87356583,2.874379184,0.267872914,DB0088710000059_,1.317242611,0.444391973,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,bumetanide,DB00887
,313288,DB00761,10048908,61,15246,24,8601,0.142330658,1.433855479,0.880135705,2.406712303,0.273057539,DB0076110048908_,1.29807274,0.360366955,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,potassium chloride,DB00761
,313305,DB00480,10048049,46,67382,17,67645,0.000220943,2.716567461,1.527686485,5.05409246,0.001566624,DB0048010048049_,6.458832369,0.999369121,NA,10048049,Wrist fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,313343,DB00706,10005724,6,1069,45,15880,0.136740025,1.980575776,0.688925674,4.670545112,0.26515137,DB0070610005724_,1.32745441,0.683387598,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,tamsulosin,DB00706
,313396,DB00264,10019075,36,29571,33,24859,0.718830472,0.917079714,0.555607684,1.518224242,0.833914209,DB0026410019075_,0.181624748,-0.086560881,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,313428,DB00338,10043431,41,33633,17,22255,0.10870689,1.595853409,0.886604241,2.99680428,0.224080323,DB0033810043431_,1.495750708,0.467408646,NA,10043431,Thinking abnormal,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,313506,DB09104,10069339,39,1011,34,838,0.904720182,0.950774635,0.579058492,1.567966275,0.957638981,DB0910410069339_,0.043284419,-0.050478222,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,magnesium hydroxide,DB09104
,313515,DB00005,10076309,72,128010,35,42384,0.072698377,0.681120172,0.448699436,1.051467549,0.166018839,DB0000510076309_,1.79565401,-0.384016524,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,313579,DB01076,10039897,39,25708,17,25566,0.004551205,2.281555062,1.260339087,4.302077618,0.018943533,DB0107610039897_,3.966292674,0.824857255,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,313767,DB00230,10007697,52,19622,11,8640,0.027499822,2.081476689,1.072262982,4.426179034,0.079101862,DB0023010007697_,2.537018862,0.733077588,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,313791,DB00814,10046306,78,8209,23,3392,0.186658765,1.401206642,0.868859589,2.342628875,0.332305573,DB0081410046306_,1.101700333,0.337333753,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,meloxicam,DB00814
,313796,DB01592,10046306,51,6225,8,3059,0.001174615,3.132411787,1.473147029,7.651874756,0.006290698,DB0159210046306_,5.068683323,1.141803247,female,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,iron,DB01592
,313864,DB04868,10013709,53,1588,57,1459,0.438088707,0.85433493,0.572360257,1.273333621,0.606476097,DB0486810013709_,0.500089962,-0.157431972,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,nilotinib,DB04868
,313880,DB01281,10037153,65,8867,18,1780,0.237019416,0.7249351,0.423558716,1.301924744,0.394357219,DB0128110037153_,0.930498134,-0.321673146,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,abatacept,DB01281
,313881,DB08904,10037153,241,11369,59,3500,0.129850402,1.257482287,0.939811696,1.705779817,0.25545377,DB0890410037153_,1.364713823,0.229111537,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,certolizumab pegol,DB08904
,313884,DB08904,10040753,259,11351,49,3510,0.001357276,1.634367464,1.197370097,2.271421537,0.007083433,DB0890410040753_,4.949996576,0.491255857,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,313888,DB08904,10046306,89,11521,22,3537,0.431256593,1.241950558,0.77047469,2.083981247,0.599655066,DB0890410046306_,0.511400679,0.216683174,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,313911,DB00422,10049414,19,3416,36,2913,0.004239455,0.450115822,0.243316553,0.807829,0.017906809,DB0042210049414_,4.022574223,-0.798250347,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,313987,DB00687,10016173,65,921,111,974,0.003425026,0.619428518,0.44281771,0.860854684,0.015062208,DB0068710016173_,4.195566438,-0.478957971,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,fludrocortisone,DB00687
,313990,DB00471,10023232,119,14070,30,5435,0.03492985,1.532286234,1.018047632,2.372547348,0.095291241,DB0047110023232_,2.350817383,0.42676089,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,314152,DB00635,10001488,20,33033,32,23762,0.004694813,0.449590583,0.243619924,0.810809874,0.019444286,DB0063510001488_,3.940202039,-0.799417925,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,prednisone,DB00635
,314284,DB00425,10076309,108,12587,42,7442,0.021785721,1.520313884,1.053953671,2.228882709,0.066135899,DB0042510076309_,2.716043577,0.418916816,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,314305,DB06605,10013786,52,14021,24,13009,0.00393448,2.010224799,1.216349512,3.41184675,0.01684878,DB0660510013786_,4.08347703,0.698246556,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,apixaban,DB06605
,314331,DB00333,10038695,28,3043,59,3093,0.001589047,0.48243076,0.295339196,0.771108165,0.008050907,DB0033310038695_,4.821970541,-0.728917871,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methadone,DB00333
,314396,DB09035,10033645,36,4690,43,6647,0.492056409,1.186528873,0.739144811,1.894848799,0.65501299,DB0903510033645_,0.423100211,0.171032131,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,nivolumab,DB09035
,314407,DB09035,10047700,140,4586,147,6543,0.010775814,1.358735882,1.066784215,1.729923012,0.037795208,DB0903510047700_,3.275572953,0.306554769,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,nivolumab,DB09035
,314421,DB11988,10013968,123,3021,22,1204,0.000317094,2.227882625,1.399263821,3.703006079,0.002110614,DB1198810013968_,6.160776146,0.801051639,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ocrelizumab,DB11988
,314438,DB11988,10028813,113,3031,28,1198,0.028226681,1.59497208,1.040395103,2.520401754,0.080755191,DB1198810028813_,2.516333038,0.466856231,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ocrelizumab,DB11988
,314455,DB11988,10047700,47,3097,14,1212,0.472849572,1.313699534,0.707903876,2.593667372,0.638806646,DB1198810047700_,0.448153459,0.272847229,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ocrelizumab,DB11988
,314463,DB00635,10050528,26,33027,30,23764,0.079284156,0.623613944,0.354162215,1.091231078,0.177209527,DB0063510050528_,1.730422479,-0.472223782,NA,10050528,Ejection fraction decreased,10022891,Investigations,Inv,prednisone,DB00635
,314541,DB00196,10076309,36,5047,20,3265,0.680891346,1.164392234,0.654956876,2.126937595,0.807023985,DB0019610076309_,0.21440189,0.152199263,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fluconazole,DB00196
,314563,DB00437,10039906,31,6890,56,11490,0.824426762,0.923149795,0.574682702,1.458342689,0.906981582,DB0043710039906_,0.097633136,-0.079963766,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,314566,DB01060,10039906,46,8541,33,5048,0.414750831,0.823882947,0.514731975,1.331890313,0.58396366,DB0106010039906_,0.537916524,-0.193726814,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,amoxicillin,DB01060
,314646,DB00112,10013946,41,5892,21,4070,0.300741938,1.348600817,0.777392366,2.406030404,0.46701346,DB0011210013946_,0.761397199,0.299067623,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,bevacizumab,DB00112
,314661,DB00364,10022437,48,2702,29,1371,0.467018967,0.839885104,0.516349696,1.387934109,0.633546323,DB0036410022437_,0.45642216,-0.174490177,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,sucralfate,DB00364
,314948,DB00441,10069339,57,2217,66,1828,0.066339075,0.71216629,0.487895909,1.036740205,0.154784305,DB0044110069339_,1.865722712,-0.339443841,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,gemcitabine,DB00441
,314952,DB01276,10013700,56,1961,19,1492,0.001993179,2.241964835,1.305314587,4.013563868,0.009695653,DB0127610013700_,4.636077608,0.80735264,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,exenatide,DB01276
,314988,DB00904,10003591,34,23035,17,14439,0.475483418,1.253624195,0.680914831,2.393739364,0.641091646,DB0090410003591_,0.444582859,0.226038712,NA,10003591,Ataxia,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,315005,DB00695,10012267,45,28004,30,20498,0.726920936,1.09797322,0.67640002,1.805703865,0.840298033,DB0069510012267_,0.173998649,0.093465953,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,315022,DB00853,10016173,27,1794,49,2217,0.129644496,0.681006812,0.407496053,1.116231964,0.255153725,DB0085310016173_,1.365889073,-0.38418297,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,temozolomide,DB00853
,315060,DB00316,10049564,35,65439,25,36928,0.419844529,0.790053385,0.459466181,1.377227153,0.588738747,DB0031610049564_,0.529772746,-0.23565476,NA,10049564,Impaired driving ability,10041244,Social circumstances,SocCi,acetaminophen,DB00316
,315087,DB08820,10012378,42,4359,34,3511,1,0.994980264,0.616505495,1.616305353,1,DB0882010012378_,0,-0.005032378,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ivacaftor,DB08820
,315088,DB11065,10012378,49,3137,24,2664,0.032685124,1.733661352,1.040259994,2.962900349,0.090591902,DB1106510012378_,2.40139045,0.55023556,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,pancrelipase amylase,DB11065
,315190,DB00437,10021015,44,6877,49,11497,0.053399684,1.501121986,0.974888547,2.305553107,0.131375019,DB0043710021015_,2.029699304,0.406212819,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,allopurinol,DB00437
,315192,DB01109,10021015,34,4378,25,4245,0.299781596,1.318638978,0.762427137,2.309812066,0.465816934,DB0110910021015_,0.763962567,0.276600127,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,heparin,DB01109
,315197,DB09153,10021015,72,7727,37,5662,0.080503347,1.425864409,0.944843788,2.184183007,0.179271444,DB0915310021015_,1.718854177,0.354778233,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,sodium chloride,DB09153
,315263,DB00264,10038669,88,29519,57,24835,0.133128995,1.298876066,0.919904852,1.846583358,0.260102994,DB0026410038669_,1.346677596,0.261499326,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metoprolol,DB00264
,315276,DB01109,10039906,25,4387,44,4226,0.01561651,0.547371112,0.320448783,0.916077234,0.050880688,DB0110910039906_,2.978271834,-0.602628257,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,heparin,DB01109
,315353,DB00996,10031009,80,38873,28,22397,0.021452791,1.646153159,1.058090097,2.631151612,0.065347852,DB0099610031009_,2.728030715,0.498441147,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,315450,DB14500,10047571,65,7744,18,4055,0.014658263,1.890799588,1.106180253,3.392048121,0.04841574,DB1450010047571_,3.027930319,0.636999802,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,potassium,DB14500
,315462,DB00186,10043417,35,16866,25,9983,0.504601099,0.828675473,0.481687739,1.445290061,0.66555134,DB0018610043417_,0.407139499,-0.187926668,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,315477,DB00268,10000081,41,2934,16,1529,0.399409077,1.335331859,0.730400353,2.557926103,0.569269472,DB0026810000081_,0.563401368,0.289179845,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ropinirole,DB00268
,315483,DB00169,10047482,53,38638,21,18154,0.617917916,1.185790136,0.702984782,2.070381502,0.758853874,DB0016910047482_,0.275946044,0.170409334,NA,10047482,Viral upper respiratory tract infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,315486,DB00316,10047482,64,65410,22,36931,0.043406368,1.642487431,0.997891478,2.801082376,0.112446294,DB0031610047482_,2.185279562,0.496211819,NA,10047482,Viral upper respiratory tract infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,315487,DB00338,10047482,39,33635,22,22250,0.602152025,1.172642577,0.678103438,2.077122597,0.746241313,DB0033810047482_,0.292706255,0.159259815,NA,10047482,Viral upper respiratory tract infection,10021881,Infections and infestations,Infec,omeprazole,DB00338
,315539,DB00635,10048865,60,32993,47,23747,0.695248093,0.918842983,0.616561884,1.376529113,0.816560818,DB0063510048865_,0.202653883,-0.084640028,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,prednisone,DB00635
,315555,DB00331,10023424,39,24907,14,20738,0.005491714,2.319336414,1.231572499,4.625690968,0.022048221,DB0033110023424_,3.814523351,0.841281116,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,metformin,DB00331
,315556,DB00999,10023424,48,21382,7,12232,0.000119962,3.922639329,1.764047091,10.27918301,0.000931111,DB0099910023424_,6.979132121,1.366764725,female,10023424,Kidney infection,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,315569,DB00443,10016173,43,2103,22,1168,0.795238752,1.085531562,0.631579967,1.915465317,0.889123571,DB0044310016173_,0.117519053,0.082069786,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,betamethasone,DB00443
,315570,DB00581,10016173,87,2026,60,2009,0.035648167,1.437702228,1.016599729,2.04452455,0.096774178,DB0058110016173_,2.335375079,0.363046164,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,lactulose,DB00581
,315600,DB01234,10021027,32,31593,20,32868,0.072888215,1.66454623,0.923035212,3.071733318,0.166345629,DB0123410021027_,1.793687553,0.509552552,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,315716,DB00490,10012174,37,4033,16,1560,0.758402928,0.894521363,0.483855275,1.727590842,0.865137628,DB0049010012174_,0.144866677,-0.111466493,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,buspirone,DB00490
,315731,DB00047,10019303,54,9231,27,8491,0.01000562,1.839602342,1.137511303,3.04029178,0.035581105,DB0004710019303_,3.335940553,0.60954943,NA,10019303,Heart rate increased,10022891,Investigations,Inv,insulin glargine,DB00047
,316018,DB00051,10024670,34,25697,26,11394,0.048691989,0.579836314,0.337603874,1.006732451,0.122586939,DB0005110024670_,2.098934794,-0.545009432,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,adalimumab,DB00051
,316033,DB00787,10061394,33,16967,24,17224,0.233949645,1.395807486,0.799975322,2.469209785,0.39076959,DB0078710061394_,0.939637178,0.333473091,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,316037,DB06643,10001949,43,52378,17,7498,0.001168506,0.362098257,0.202142966,0.67756482,0.006266922,DB0664310001949_,5.072469956,-1.015839676,male,10001949,Amnesia,10029205,Nervous system disorders,Nerv,denosumab,DB06643
,316099,DB00993,10024384,34,3215,22,1597,0.391904534,0.767749693,0.43452879,1.382857109,0.561771864,DB0099310024384_,0.576659447,-0.264291519,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,azathioprine,DB00993
,316180,DB01275,10005557,36,3943,21,3328,0.184894918,1.446829706,0.820313209,2.613909934,0.330014798,DB0127510005557_,1.108617782,0.369374753,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,hydralazine,DB01275
,316187,DB08895,10012601,62,28052,12,6634,0.656795497,1.22185362,0.651650088,2.492584304,0.790162695,DB0889510012601_,0.235516411,0.200369066,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,tofacitinib,DB08895
,316188,DB01275,10017577,43,3936,29,3320,0.405713219,1.25066189,0.761161165,2.082319769,0.575291145,DB0127510017577_,0.552879027,0.223672923,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,316234,DB08895,10048439,137,27977,8,6638,3.72927462201773e-06,4.06310378,2.00357457,9.602790423,4.56642995941122e-05,DB0889510048439_,9.994193756,1.401947159,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,316242,DB08895,10061224,95,28019,15,6631,0.180457499,1.498827386,0.863775102,2.784719052,0.324418669,DB0889510061224_,1.125720408,0.40468306,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,316257,DB00788,10029331,83,9273,50,5011,0.584096201,0.897050843,0.622970671,1.303172134,0.731982581,DB0078810029331_,0.311998562,-0.108642738,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,naproxen,DB00788
,316266,DB00316,10061159,42,65432,10,36943,0.013220163,2.37130487,1.170608116,5.300993222,0.044470437,DB0031610061159_,3.112930648,0.863440382,NA,10061159,Foot deformity,10028395,Musculoskeletal and connective tissue disorders,Musc,acetaminophen,DB00316
,316269,DB00381,10060945,36,29324,17,22870,0.096619671,1.651550012,0.90369149,3.136435685,0.205706354,DB0038110060945_,1.581305591,0.501714248,NA,10060945,Bacterial infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,316284,DB00264,10024570,56,29551,29,24863,0.037911217,1.624674877,1.019586799,2.639970269,0.101471039,DB0026410024570_,2.287981851,0.48530772,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,metoprolol,DB00264
,316436,DB00231,10047513,43,3253,9,2130,0.000871735,3.127828283,1.499966422,7.313235932,0.004920305,DB0023110047513_,5.314384678,1.140338924,female,10047513,Vision blurred,10015919,Eye disorders,Eye,temazepam,DB00231
,316463,DB00581,10039906,30,2083,30,2039,1,0.978878056,0.567829577,1.68734699,1,DB0058110039906_,0,-0.021348204,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,lactulose,DB00581
,316517,DB05676,10033775,111,47018,41,25288,0.040864217,1.456086844,1.00887873,2.138203888,0.107368648,DB0567610033775_,2.23148706,0.375752594,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,316538,DB00341,10003246,69,11336,10,5058,0.000217784,3.078424397,1.575631539,6.709821037,0.001548193,DB0034110003246_,6.470666888,1.124417907,female,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,cetirizine,DB00341
,316564,DB05259,10008190,42,11228,16,2712,0.133506027,0.634064275,0.348461421,1.210048644,0.260636467,DB0525910008190_,1.344628688,-0.45560495,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,glatiramer,DB05259
,316567,DB01240,10028372,54,5697,12,1564,0.651318146,1.235349903,0.650706566,2.543502214,0.785766952,DB0124010028372_,0.241095029,0.211354252,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,epoprostenol,DB01240
,316602,DB01202,10013700,97,6617,45,5673,0.000654948,1.847945203,1.282379875,2.698559435,0.003876451,DB0120210013700_,5.552835345,0.614074321,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,levetiracetam,DB01202
,316611,DB00512,10001052,19,4718,53,5045,0.000200755,0.383398676,0.213961433,0.659464902,0.001445708,DB0051210001052_,6.539156099,-0.958679901,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vancomycin,DB00512
,316627,DB01137,10009887,30,7742,22,5571,1,0.981243287,0.546749987,1.787261174,1,DB0113710009887_,0,-0.018934851,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,316717,DB01222,10022000,121,9153,84,5321,0.215844948,0.8374238,0.627340239,1.122168318,0.368396121,DB0122210022000_,0.998596503,-0.177425004,NA,10022000,Influenza,10021881,Infections and infestations,Infec,budesonide,DB01222
,316723,DB00642,10051398,39,495,44,489,0.570021499,0.875729525,0.543644126,1.406224731,0.720805095,DB0064210051398_,0.327386505,-0.132697997,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pemetrexed,DB00642
,316760,DB09033,10025482,39,2585,26,1643,0.898181387,0.953414814,0.563423855,1.637851608,0.956353692,DB0903310025482_,0.044627464,-0.047705198,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,vedolizumab,DB09033
,316851,DB00993,10021097,51,3198,16,1603,0.117000035,1.597595839,0.892939091,3.011571471,0.236614664,DB0099310021097_,1.44132235,0.468499899,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,azathioprine,DB00993
,316938,DB00688,10069339,164,6326,194,5184,0.000670237,0.69278174,0.557388085,0.860215584,0.003953586,DB0068810069339_,5.533132255,-0.36704028,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,mycophenolate mofetil,DB00688
,316939,DB00993,10069339,45,3204,41,1578,0.005396892,0.540608615,0.344564447,0.850345214,0.021733923,DB0099310069339_,3.828880974,-0.615059709,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,azathioprine,DB00993
,316959,DB00188,10013786,48,7838,25,8803,0.002036183,2.156303572,1.302006576,3.653022778,0.009866542,DB0018810013786_,4.618605824,0.768395446,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,bortezomib,DB00188
,316963,DB08910,10020765,25,16719,38,17450,0.16526606,0.686669878,0.397112156,1.168124528,0.304490827,DB0891010020765_,1.189114317,-0.375901629,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,316969,DB00787,10060795,41,16959,22,17226,0.016150515,1.89293073,1.101000555,3.338136,0.052208983,DB0078710060795_,2.952500719,0.638126279,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,acyclovir,DB00787
,317025,DB08827,10065154,270,892,116,466,0.126270531,1.215846586,0.946455798,1.56807553,0.250489433,DB0882710065154_,1.384338543,0.195440613,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,lomitapide,DB08827
,317026,DB13961,10065154,114,9343,52,6362,0.016959282,1.492787477,1.06452201,2.117693104,0.054280028,DB1396110065154_,2.913598929,0.400645162,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,fish oil,DB13961
,317048,DB00213,10060800,100,18795,31,13390,2.44441061683861e-05,2.298067249,1.521438436,3.560819803,0.000236915,DB0021310060800_,8.347809363,0.832068443,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,pantoprazole,DB00213
,317121,DB09035,10042772,36,4690,47,6643,0.73793066,1.084907289,0.681606997,1.713900074,0.849048255,DB0903510042772_,0.163639256,0.081494535,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,nivolumab,DB09035
,317174,DB00153,10061623,40,7383,17,3422,0.886635319,1.090571154,0.603379035,2.054704517,0.952901543,DB0015310061623_,0.048243693,0.086701554,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,317203,DB00588,10014184,30,16494,23,8445,0.148095192,0.667822203,0.374855814,1.204744963,0.281364807,DB0058810014184_,1.268103205,-0.403733304,NA,10014184,Eczema,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone propionate,DB00588
,317379,DB01285,10048959,54,1222,19,590,0.306891308,1.371996624,0.791777851,2.474427243,0.473929847,DB0128510048959_,0.746695971,0.316267068,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,corticotropin,DB01285
,317395,DB01136,10049848,58,9826,70,11045,0.722880268,0.93134312,0.645361414,1.339718287,0.836952223,DB0113610049848_,0.177988292,-0.071127519,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,317461,DB06228,10011078,16,15896,34,16042,0.015334059,0.474923402,0.244680193,0.884608377,0.050178119,DB0622810011078_,2.992176217,-0.744601747,NA,10011078,Coronary artery disease,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,317515,DB00019,10063829,736,18276,405,9124,0.124212825,0.907255881,0.800406755,1.029465337,0.247380974,DB0001910063829_,1.396825726,-0.09733075,NA,10063829,Device malfunction,10077536,Product issues,Prod,pegfilgrastim,DB00019
,317520,DB00285,10043417,41,10910,16,3702,0.647690328,0.869539009,0.476785185,1.662028004,0.78282977,DB0028510043417_,0.244840014,-0.139792082,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,317567,DB11089,10016807,78,10097,48,8359,0.126526935,1.345265084,0.925982588,1.972026854,0.250839875,DB1108910016807_,1.382940491,0.296591082,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,docusate,DB11089
,317603,DB00182,10020751,48,5146,16,2836,0.088247804,1.653227553,0.920398731,3.12501715,0.192329797,DB0018210020751_,1.648543687,0.50272947,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,amphetamine,DB00182
,317647,DB00999,10051118,56,21374,21,12218,0.122412249,1.524325896,0.907993536,2.651890405,0.244899034,DB0099910051118_,1.406909259,0.421552277,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,317742,DB00734,10022086,31,4019,39,4863,0.904555496,0.961794665,0.57907502,1.585084804,0.957573483,DB0073410022086_,0.043352816,-0.038954297,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,317743,DB00761,10022086,71,15236,7,8618,7.64700459865284e-08,5.737640328,2.642655603,14.79710333,1.42100753535235e-06,DB0076110022086_,13.46414441,1.747048033,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,317744,DB01060,10022086,54,8533,16,5065,0.012858514,2.003231289,1.128053008,3.753749597,0.04349045,DB0106010022086_,3.135213898,0.694761521,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,317824,DB00207,10012174,65,9015,38,5417,0.919082289,1.027833168,0.677440086,1.579019573,0.964259603,DB0020710012174_,0.036394723,0.027452866,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,azithromycin,DB00207
,317847,DB01175,10037162,57,10667,13,4879,0.020000412,2.005410717,1.083307871,3.997066995,0.061761141,DB0117510037162_,2.784480892,0.695848886,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,317946,DB00338,10007697,52,33622,14,22258,0.001578231,2.458834734,1.342350794,4.80567864,0.008010774,DB0033810007697_,4.826967919,0.899687552,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,317947,DB00451,10007697,61,47210,12,15407,0.133511117,1.658878175,0.884101064,3.38616736,0.260636467,DB0045110007697_,1.344628688,0.506141576,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,317952,DB00999,10007697,43,21387,9,12230,0.003615832,2.732058748,1.313128013,6.376226786,0.015727644,DB0099910007697_,4.152335333,1.005055445,female,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,318000,DB00526,10020642,17,1581,40,1854,0.015645984,0.498491291,0.263882238,0.903594637,0.050951457,DB0052610020642_,2.976881926,-0.696169159,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,oxaliplatin,DB00526
,318022,DB01033,10035664,31,1151,39,1265,0.628159968,0.873647052,0.523240076,1.447537435,0.767462339,DB0103310035664_,0.264665871,-0.135078816,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,mercaptopurine,DB01033
,318174,DB00795,10066901,196,4373,59,1444,0.60382377,1.096945105,0.810662499,1.502911954,0.747337482,DB0079510066901_,0.291238412,0.092529139,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,318175,DB06196,10022086,38,1002,16,267,0.130387495,0.633104633,0.338498774,1.235920238,0.256280214,DB0619610022086_,1.361483849,-0.457119573,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,icatibant,DB06196
,318209,DB00795,10010264,101,4468,30,1473,0.682782618,1.10989521,0.728501257,1.736322433,0.808202337,DB0079510010264_,0.212942834,0.104265606,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,318210,DB00795,10013968,84,4485,24,1479,0.57590276,1.154151541,0.722711359,1.907734016,0.725328417,DB0079510013968_,0.321130738,0.143365477,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sulfasalazine,DB00795
,318230,DB00864,10066260,27,6842,36,8356,0.800144714,0.915939482,0.534240021,1.553110246,0.891935108,DB0086410066260_,0.114361898,-0.087804984,NA,10066260,Acute graft versus host disease,10021428,Immune system disorders,Immun,tacrolimus,DB00864
,318318,DB00514,10025482,40,2126,22,1514,0.364781116,1.294702876,0.747653979,2.297371755,0.534388833,DB0051410025482_,0.626631553,0.25828123,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,dextromethorphan,DB00514
,318357,DB06228,10062355,87,15825,63,16013,0.049185385,1.397337266,0.998029629,1.965905288,0.123456632,DB0622810062355_,2.091865341,0.334568473,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,318372,DB00490,10037153,57,4013,15,1561,0.188924643,1.478114349,0.822694792,2.819713585,0.335192997,DB0049010037153_,1.093048803,0.390767187,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,buspirone,DB00490
,318423,DB00331,10014011,49,24897,24,20728,0.034034025,1.69976638,1.022676668,2.897564103,0.093468221,DB0033110014011_,2.37013378,0.530490818,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,metformin,DB00331
,318461,DB08904,10011906,85,11525,56,3503,1.45429896077551e-05,0.461369195,0.324723693,0.660009432,0.000150943,DB0890410011906_,8.798610017,-0.773556699,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,318542,DB00973,10020937,39,3812,23,2998,0.305093232,1.333512904,0.774937917,2.344254568,0.471894527,DB0097310020937_,0.750999778,0.287816741,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,ezetimibe,DB00973
,318573,DB00051,10050296,61,25670,21,11399,0.340058797,1.289842684,0.773901601,2.231312153,0.509214059,DB0005110050296_,0.674886803,0.254520261,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,318589,DB00005,10061026,58,128024,63,42356,1.41170232145915e-10,0.304589814,0.209457056,0.442258472,4.48960623346082e-09,DB0000510061026_,19.22150084,-1.188789281,male,10061026,Cardiac operation,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,318603,DB00051,10020040,75,25656,26,11394,0.330968108,1.281035885,0.809866753,2.086779202,0.499669551,DB0005110020040_,0.693808297,0.247669036,NA,10020040,Hidradenitis,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,318654,DB00921,10010774,82,5763,52,4851,0.116700936,1.32733709,0.924370247,1.9208164,0.236169235,DB0092110010774_,1.443206632,0.283174747,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,buprenorphine,DB00921
,318655,DB01432,10010774,37,1254,15,655,0.461278693,1.288279019,0.684169924,2.546359368,0.628630483,DB0143210010774_,0.464211662,0.253307234,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,cholestyramine,DB01432
,318682,DB00695,10039897,38,28011,12,20516,0.009431706,2.319290217,1.186105635,4.87593948,0.033962929,DB0069510039897_,3.382485681,0.841261198,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,318706,DB01101,10023644,45,7544,7,3901,0.001105005,3.323941368,1.486093916,8.7443188,0.005977578,DB0110110023644_,5.119739819,1.201151238,female,10023644,Lacrimation increased,10015919,Eye disorders,Eye,capecitabine,DB01101
,318712,DB00661,10008479,36,3492,15,1580,0.879801144,1.085891831,0.577892437,2.141339932,0.949520553,DB0066110008479_,0.051798103,0.082401613,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,verapamil,DB00661
,318717,DB00661,10041349,46,3482,17,1578,0.584061333,1.226203761,0.687144901,2.28915262,0.731956334,DB0066110041349_,0.31203442,0.203923023,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,verapamil,DB00661
,318758,DB00169,10054107,48,38643,12,18163,0.051972556,1.880063053,0.983492431,3.889464101,0.128749249,DB0016910054107_,2.04988857,0.631305315,NA,10054107,Nodule,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,318793,DB09027,10000059,68,5111,90,7062,0.808017044,1.043995808,0.748885788,1.449646839,0.896432542,DB0902710000059_,0.109332235,0.043055474,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ledipasvir,DB09027
,318796,DB09027,10047513,33,5146,33,7119,0.211259096,1.383347289,0.826359361,2.315739827,0.362854597,DB0902710047513_,1.013753083,0.324506134,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ledipasvir,DB09027
,318863,DB01098,10050584,66,8083,30,7179,0.001993229,1.953865125,1.249342658,3.120719761,0.009695653,DB0109810050584_,4.636077608,0.669809526,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,rosuvastatin,DB01098
,318871,DB06228,10007739,33,15879,33,16043,1,1.010328618,0.604076267,1.689853833,1,DB0622810007739_,0,0.010275642,NA,10007739,Cataract,10015919,Eye disorders,Eye,rivaroxaban,DB06228
,318885,DB00669,10047513,45,6332,7,1090,1,1.106642521,0.493673275,2.916203742,1,DB0066910047513_,0,0.101330676,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,sumatriptan,DB00669
,318886,DB01202,10047513,41,6673,20,5698,0.039691998,1.750391343,1.000947616,3.157603221,0.105040611,DB0120210047513_,2.253408235,0.559839387,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,levetiracetam,DB01202
,318935,DB01220,10016173,34,1260,25,1111,0.512222184,1.199084631,0.689807078,2.110610836,0.672462319,DB0122010016173_,0.3968092,0.181558458,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,rifaximin,DB01220
,318937,DB00497,10016454,37,19230,21,16354,0.148197644,1.498377528,0.854057416,2.695364154,0.281508587,DB0049710016454_,1.267592328,0.404382875,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,318978,DB00231,10007515,39,3257,22,2117,0.692937956,1.152254056,0.664322019,2.04652412,0.815000299,DB0023110007515_,0.204566799,0.141720073,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,temazepam,DB00231
,318982,DB00557,10007515,118,5869,69,2998,0.390746115,0.873594935,0.641425712,1.197497841,0.56061892,DB0055710007515_,0.578713892,-0.135138472,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,hydroxyzine,DB00557
,318984,DB00741,10007515,43,4051,34,3140,1,0.980292744,0.609058683,1.58913207,1,DB0074110007515_,0,-0.019904034,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,hydrocortisone,DB00741
,318989,DB00181,10009033,40,9816,18,5853,0.344403723,1.325024649,0.741502317,2.457829577,0.513742232,DB0018110009033_,0.666033634,0.281431062,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,baclofen,DB00181
,319048,DB08895,10013950,83,28031,7,6639,0.004424781,2.808272159,1.30322142,7.204959043,0.018525861,DB0889510013950_,3.988587614,1.032569404,female,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,319125,DB00635,10035669,37,33016,38,23756,0.128742875,0.700611203,0.433137646,1.132257062,0.253841221,DB0063510035669_,1.371046322,-0.355802178,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,prednisone,DB00635
,319275,DB00213,10022972,40,18855,26,13395,0.80293428,1.092974323,0.650424769,1.866337123,0.893342905,DB0021310022972_,0.11278478,0.088902716,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,pantoprazole,DB00213
,319288,DB00316,10060968,31,65443,19,36934,0.770110067,0.920814673,0.503929524,1.725487541,0.874040593,DB0031610060968_,0.134628459,-0.082496487,NA,10060968,Arthritis infective,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,319296,DB00158,10061024,65,16750,36,8068,0.523499235,0.869697804,0.569635842,1.34677153,0.681717293,DB0015810061024_,0.383140234,-0.139609479,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,folic acid,DB00158
,319389,DB00581,10003988,58,2055,46,2023,0.320714469,1.241169239,0.824047322,1.87891989,0.488977947,DB0058110003988_,0.715437888,0.21605387,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,lactulose,DB00581
,319401,DB00581,10012378,38,2075,13,2056,0.00059644,2.895793377,1.503540059,5.942080306,0.003578094,DB0058110012378_,5.632925043,1.063259124,female,10012378,Depression,10037175,Psychiatric disorders,Psych,lactulose,DB00581
,319495,DB00907,10011906,158,980,186,1625,0.003206294,1.408337569,1.115165848,1.777209615,0.014280907,DB0090710011906_,4.248831827,0.34240998,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,cocaine,DB00907
,319526,DB04861,10037087,41,1924,27,1360,0.804897394,1.07337295,0.641064512,1.824134411,0.894427482,DB0486110037087_,0.11157145,0.07080598,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,nebivolol,DB04861
,319727,DB00909,10053762,42,778,27,454,0.702334425,0.907810755,0.538472615,1.553527072,0.821431893,DB0090910053762_,0.196706251,-0.096719342,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,zonisamide,DB00909
,319747,DB00950,10010264,97,4621,22,2034,0.00461084,1.94056082,1.207736248,3.24834845,0.019155354,DB0095010010264_,3.955173001,0.662977014,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,319790,DB00338,10076308,194,33480,112,22160,0.266061758,1.146518279,0.903328161,1.460908985,0.428191233,DB0033810076308_,0.848185378,0.136729766,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,319792,DB00455,10076308,49,9352,26,5092,1,1.026139096,0.624519679,1.722399753,1,DB0045510076308_,0,0.025803308,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,319793,DB00472,10076308,48,10711,25,4287,0.299472167,0.768466098,0.463848005,1.302407877,0.465459948,DB0047210076308_,0.764729226,-0.263358832,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,319798,DB01222,10076308,45,9229,20,5385,0.367360983,1.312821905,0.758535727,2.349655852,0.537030863,DB0122210076308_,0.621699714,0.272178946,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,budesonide,DB01222
,319808,DB00158,10022081,63,16752,12,8092,0.001825336,2.535914652,1.353927643,5.16896852,0.009027087,DB0015810022081_,4.707525558,0.930554381,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,319816,DB01234,10018964,40,31585,62,32826,0.047995881,0.670517227,0.438806246,1.014171747,0.121345811,DB0123410018964_,2.10911087,-0.399705884,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,319818,DB01234,10062352,50,31575,36,32852,0.105126699,1.44504395,0.922580383,2.283966578,0.218735042,DB0123410062352_,1.519894137,0.368139737,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,319971,DB00333,10038669,93,2978,91,3061,0.76497286,1.050473017,0.774654354,1.424809019,0.87033336,DB0033310038669_,0.138878969,0.049240556,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methadone,DB00333
,319980,DB01234,10048592,33,31592,40,32848,0.558948407,0.857802153,0.524047756,1.39540468,0.711767986,DB0123410048592_,0.340003283,-0.153381798,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,dexamethasone,DB01234
,320056,DB09140,10044565,53,3688,17,1781,0.158394638,1.505463685,0.855064985,2.781887773,0.295329177,DB0914010044565_,1.219664691,0.409100947,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,oxygen,DB09140
,320102,DB01281,10069327,58,8874,12,1786,0.873182721,0.972766676,0.515379587,1.994325346,0.944720193,DB0128110069327_,0.056866487,-0.027611024,NA,10069327,Product quality issue,10077536,Product issues,Prod,abatacept,DB01281
,320136,DB06605,10028836,55,14018,37,12996,0.143652761,1.378092294,0.891499716,2.152124544,0.275031891,DB0660510028836_,1.29086822,0.320700147,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,320152,DB05676,10005557,90,47039,40,25289,0.357445169,1.209605723,0.824428568,1.802929902,0.527152907,DB0567610005557_,0.640264626,0.190294458,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,apremilast,DB05676
,320187,DB06186,10053762,78,2131,110,3536,0.284984671,1.176563804,0.864269585,1.595458212,0.449561715,DB0618610053762_,0.799482137,0.16259816,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ipilimumab,DB06186
,320206,DB06605,10047571,61,14012,35,12998,0.024203615,1.616697707,1.049144511,2.526423988,0.071699765,DB0660510047571_,2.635267807,0.480385616,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,apixaban,DB06605
,320207,DB00390,10061822,34,4111,22,3279,0.500742807,1.232644533,0.698793787,2.217001577,0.66229022,DB0039010061822_,0.412051421,0.209161888,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,digoxin,DB00390
,320256,DB00374,10056819,66,17650,29,5695,0.187235371,0.73434684,0.467294664,1.180238235,0.333050126,DB0037410056819_,1.099462271,-0.308773828,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,320427,DB00019,10048959,53,18959,27,9502,1,0.983803331,0.607445263,1.627884694,1,DB0001910048959_,0,-0.016329269,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,320429,DB00581,10048959,46,2067,22,2047,0.004719735,2.070320886,1.215281225,3.627932496,0.019529043,DB0058110048959_,3.935852554,0.727703612,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,lactulose,DB00581
,320512,DB00646,10021015,40,3413,11,1989,0.027747131,2.118910393,1.063998491,4.590014266,0.079665029,DB0064610021015_,2.529924569,0.750901991,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,nystatin,DB00646
,320526,DB06403,10043071,101,21370,21,6640,0.108704795,1.494347906,0.926275676,2.520367287,0.224080323,DB0640310043071_,1.495750708,0.401689929,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,ambrisentan,DB06403
,320565,DB00203,10035669,30,13848,24,8914,0.485606323,0.804645115,0.454447857,1.439192063,0.649625274,DB0020310035669_,0.431359584,-0.217353949,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,sildenafil,DB00203
,320598,DB13867,10069339,72,4478,61,2493,0.017712508,0.657125431,0.458998185,0.943452974,0.056174381,DB1386710069339_,2.879294485,-0.419880364,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,fluticasone,DB13867
,320636,DB00051,10061598,48,25683,21,11399,1,1.014484369,0.595540844,1.784522896,1,DB0005110061598_,0,0.014380473,NA,10061598,Immunodeficiency,10021428,Immune system disorders,Immun,adalimumab,DB00051
,320791,DB00668,10047899,65,10026,24,4279,0.642332395,1.155872676,0.712680515,1.933585612,0.778832076,DB0066810047899_,0.24995982,0.144855622,NA,10047899,Weight increased,10022891,Investigations,Inv,epinephrine,DB00668
,320986,DB00338,10019465,36,33638,17,22255,0.265095472,1.401032922,0.766596323,2.660762959,0.427054484,DB0033810019465_,0.850843676,0.337209766,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,320996,DB01136,10027091,58,9826,28,11087,0.000193967,2.337180119,1.463155104,3.815125505,0.001404026,DB0113610027091_,6.568411263,0.848945126,NA,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,321074,DB00273,10064355,42,8439,11,2182,1,0.987235315,0.498483391,2.129783843,1,DB0027310064355_,0,-0.012846854,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,topiramate,DB00273
,321116,DB01098,10019974,50,8099,18,7191,0.000601888,2.466110564,1.412438694,4.496027286,0.003607071,DB0109810019974_,5.624859201,0.902642239,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,rosuvastatin,DB01098
,321138,DB00741,10052904,43,4051,9,3165,0.000104921,3.732199689,1.791107136,8.71879128,0.000831497,DB0074110052904_,7.092283027,1.316997789,female,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocortisone,DB00741
,321216,DB00588,10017413,68,16456,36,8432,0.917371718,0.967831238,0.636458493,1.494023015,0.963310853,DB0058810017413_,0.037379123,-0.032697547,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,321252,DB00814,10076309,64,8223,21,3394,0.403361037,1.257844161,0.756619419,2.172073676,0.573084234,DB0081410076309_,0.556722569,0.229399272,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,meloxicam,DB00814
,321281,DB00627,10003549,22,1307,61,1538,0.000461837,0.424528403,0.246787031,0.705829317,0.002891017,DB0062710003549_,5.846146811,-0.856776366,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,niacin,DB00627
,321290,DB00537,10061623,33,7524,23,4275,0.486778592,0.815243007,0.463755389,1.456106284,0.650647104,DB0053710061623_,0.429787866,-0.204269042,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,321324,DB01015,10039906,80,9807,68,9313,0.510341491,1.117198026,0.797388599,1.569094823,0.670783383,DB0101510039906_,0.399309021,0.110823789,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,321328,DB00956,10037153,52,5762,26,3441,0.483441129,1.194396914,0.730776585,1.996551297,0.6476682,DB0095610037153_,0.434376751,0.177641383,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocodone,DB00956
,321342,DB00043,10008190,33,6380,21,2279,0.043645128,0.561383107,0.314492744,1.023270846,0.112893144,DB0004310008190_,2.181313539,-0.577351706,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,omalizumab,DB00043
,321349,DB00814,10017944,38,8249,13,3402,0.644825526,1.205486593,0.627162742,2.469447615,0.780709787,DB0081410017944_,0.24755179,0.186883297,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,meloxicam,DB00814
,321387,DB00678,10013952,85,15514,49,10675,0.333958122,1.193591922,0.829374333,1.734497399,0.503024337,DB0067810013952_,0.687116726,0.176967183,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,321408,DB00363,10049414,31,4597,50,6838,0.820242786,0.922238428,0.568536803,1.474817739,0.904288487,DB0036310049414_,0.100606847,-0.08095149,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,clozapine,DB00363
,321412,DB00007,10011224,16,1931,35,4417,0.879210563,1.045667904,0.539035691,1.945110222,0.949253441,DB0000710011224_,0.052079455,0.044655824,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,leuprolide,DB00007
,321423,DB09027,10013946,87,5092,98,7054,0.176708187,1.2297874,0.908505862,1.662398329,0.319645908,DB0902710013946_,1.140541433,0.206841309,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,ledipasvir,DB09027
,321516,DB00761,10003662,48,15259,29,8596,0.812270291,0.93242791,0.575670887,1.534658531,0.899071824,DB0076110003662_,0.106392355,-0.069963438,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,321521,DB00390,10005557,32,4113,26,3275,1,0.980004642,0.564555133,1.715812921,1,DB0039010005557_,0,-0.020197971,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,digoxin,DB00390
,321524,DB00341,10006093,26,11379,38,5030,2.24039686123719e-06,0.30245625,0.176128781,0.511971579,2.92833572837492e-05,DB0034110006093_,10.43849121,-1.19581864,male,10006093,Bradycardia,10007541,Cardiac disorders,Card,cetirizine,DB00341
,321540,DB00343,10013781,47,8689,19,5076,0.201246946,1.445057234,0.830869831,2.610412366,0.350478763,DB0034310013781_,1.048455166,0.368148929,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,321627,DB09146,10013968,110,678,46,381,0.126756725,1.343469598,0.921049628,1.98423154,0.251115505,DB0914610013968_,1.381842267,0.29525552,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iron sucrose,DB09146
,321643,DB09027,10011224,59,5120,57,7095,0.058503664,1.434297364,0.977752602,2.105578765,0.140686044,DB0902710011224_,1.961224507,0.360675088,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ledipasvir,DB09027
,321671,DB00313,10007515,53,1186,34,1483,0.002929176,1.948683541,1.234181263,3.11390774,0.013248453,DB0031310007515_,4.323874516,0.667154037,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,valproic acid,DB00313
,321706,DB00656,10013781,65,11948,33,6586,0.751586217,1.085743865,0.702802002,1.706389351,0.859740615,DB0065610013781_,0.151124545,0.082265342,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,trazodone,DB00656
,321882,DB00737,10061428,61,2740,16,916,0.427822746,1.274453112,0.721218062,2.380676531,0.596354496,DB0073710061428_,0.516919997,0.242517154,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,meclizine,DB00737
,322127,DB06273,10035528,33,5062,25,1385,0.000290954,0.36123448,0.207555214,0.635944822,0.001967514,DB0627310035528_,6.230984416,-1.018228001,male,10035528,Platelet count decreased,10022891,Investigations,Inv,tocilizumab,DB06273
,322165,DB01611,10016807,51,11862,10,2351,1,1.010798972,0.506493215,2.236426877,1,DB0161110016807_,0,0.01074108,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,hydroxychloroquine,DB01611
,322166,DB08895,10016807,60,28054,9,6637,0.222994275,1.57716666,0.777318113,3.617258043,0.377206031,DB0889510016807_,0.97496374,0.455629984,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,tofacitinib,DB08895
,322205,DB06605,10007739,57,14016,32,13001,0.025235346,1.652219783,1.052749979,2.634568483,0.074017861,DB0660510007739_,2.603448848,0.502119707,NA,10007739,Cataract,10015919,Eye disorders,Eye,apixaban,DB06605
,322267,DB08907,10018484,81,4172,87,3823,0.311637687,0.853168642,0.620440781,1.17219221,0.479038006,DB0890710018484_,0.73597534,-0.158798047,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,canagliflozin,DB08907
,322368,DB00193,10013663,49,19271,47,8655,0.00024069,0.468235481,0.307063556,0.71470389,0.001681158,DB0019310013663_,6.38827233,-0.758783945,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,322400,DB00497,10027951,36,19231,20,16355,0.140396311,1.530787845,0.86235924,2.792017276,0.270419919,DB0049710027951_,1.307779271,0.425782534,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,322437,DB00193,10043417,52,19268,15,8687,0.145856628,1.5629279,0.865935289,2.990913669,0.278250336,DB0019310043417_,1.279234083,0.446560921,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,322439,DB00273,10043417,48,8433,16,2177,0.354938752,0.774477664,0.431110407,1.464086874,0.524751961,DB0027310043417_,0.644829584,-0.255566459,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,322443,DB00471,10043417,53,14136,22,5443,0.796360226,0.927607004,0.553952331,1.60332871,0.889752977,DB0047110043417_,0.116811408,-0.075147123,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,montelukast,DB00471
,322516,DB01268,10023232,29,2114,32,3098,0.294997595,1.327988477,0.772567249,2.27397882,0.46087621,DB0126810023232_,0.774625798,0.283665374,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,sunitinib,DB01268
,322574,DB08932,10037833,59,19384,14,6583,0.280580922,1.431164873,0.788795946,2.777920825,0.444415157,DB0893210037833_,0.810996116,0.358488709,NA,10037833,Rales,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,322641,DB00788,10064355,56,9300,16,5045,0.025157959,1.898579478,1.072397289,3.549395891,0.073844439,DB0078810064355_,2.605794576,0.641105963,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,322711,DB00425,10013395,43,12652,27,7457,0.805042984,0.938666451,0.566419651,1.581159197,0.894473299,DB0042510013395_,0.111520227,-0.06329508,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,322742,DB06605,10007554,106,13967,82,12951,0.241248949,1.198640259,0.889062244,1.620879899,0.399386382,DB0660510007554_,0.917825956,0.181187797,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,apixaban,DB06605
,322743,DB01273,10029412,76,1964,55,1220,0.410337497,0.858404318,0.594078665,1.24702282,0.579751524,DB0127310029412_,0.545155674,-0.152680058,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,varenicline,DB01273
,322830,DB00091,10030041,142,5368,17,2653,1.03566903135446e-10,4.127386354,2.482323325,7.300185724,3.36704520583203e-09,DB0009110030041_,19.50923027,1.417644362,female,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,cyclosporine,DB00091
,322838,DB00318,10007617,31,4252,35,1804,0.000113086,0.375850217,0.223370549,0.629697308,0.000886638,DB0031810007617_,7.028074111,-0.978564575,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,codeine,DB00318
,323009,DB00996,10048908,82,38871,40,22385,0.451603542,1.180522613,0.799186299,1.769394623,0.619249784,DB0099610048908_,0.47924656,0.165957232,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,gabapentin,DB00996
,323118,DB01076,10037855,44,25703,35,25548,0.368011732,1.249553803,0.783130165,2.007441734,0.537727965,DB0107610037855_,0.620402488,0.22278653,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,atorvastatin,DB01076
,323138,DB00814,10033295,38,8249,33,3382,0.002313637,0.472130901,0.287790966,0.778246949,0.010952533,DB0081410033295_,4.514184553,-0.750499,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,meloxicam,DB00814
,323211,DB01015,10029366,71,9816,64,9317,0.795838991,1.052993736,0.739494207,1.501876385,0.889450459,DB0101510029366_,0.117151469,0.051637284,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,323242,DB00563,10038683,65,46581,10,15338,0.022130147,2.140136233,1.092287231,4.673777083,0.066930263,DB0056310038683_,2.704104054,0.760869487,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,323310,DB01029,10010774,38,1302,13,888,0.030578447,1.993050029,1.03137379,4.102408006,0.085990637,DB0102910010774_,2.453516856,0.689666143,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,irbesartan,DB01029
,323344,DB01136,10061623,68,9816,66,11049,0.434740952,1.159710849,0.813319296,1.654450342,0.603223581,DB0113610061623_,0.50546737,0.148170706,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,carvedilol,DB01136
,323346,DB08889,10061623,36,3129,27,3858,0.0561713,1.643834933,0.968161705,2.822017784,0.136399461,DB0888910061623_,1.992167488,0.497031886,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,323347,DB00028,10037884,65,13393,42,5573,0.032774378,0.644000409,0.429715145,0.974467953,0.090781868,DB0002810037884_,2.399295704,-0.440055918,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,human immunoglobulin g,DB00028
,323351,DB08910,10016766,48,16696,31,17457,0.04199188,1.618927952,1.009048203,2.632641212,0.109684643,DB0891010016766_,2.210145913,0.481764172,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,pomalidomide,DB08910
,323399,DB06674,10013700,145,4361,32,1458,0.034082347,1.514768655,1.021888864,2.307425266,0.093581373,DB0667410013700_,2.368923917,0.415262724,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,golimumab,DB06674
,323404,DB06674,10037153,73,4433,25,1465,0.90619847,0.964993549,0.60265358,1.592906494,0.958144782,DB0667410037153_,0.042756383,-0.035633862,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,golimumab,DB06674
,323405,DB06674,10046735,71,4435,15,1475,0.130833491,1.574057644,0.889821614,2.968345054,0.25695508,DB0667410046735_,1.358853994,0.453656772,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,golimumab,DB06674
,323555,DB01068,10035669,39,13724,52,6788,3.07598787046171e-06,0.370974582,0.238236253,0.573476926,3.87409397101514e-05,DB0106810035669_,10.15861364,-0.991621732,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,clonazepam,DB01068
,323623,DB00874,10003239,83,3252,33,1943,0.052010481,1.502639652,0.988353007,2.332151194,0.128819363,DB0087410003239_,2.04934414,0.40722333,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,guaifenesin,DB00874
,323670,DB00169,10061161,44,38647,7,18168,0.004010554,2.954875204,1.320019623,7.777066003,0.017115994,DB0016910061161_,4.067741947,1.083456418,female,10061161,Pelvic fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,323671,DB00316,10061161,61,65413,12,36941,0.000336801,2.870701399,1.530095211,5.858475458,0.002220974,DB0031610061161_,6.10980952,1.05455639,female,10061161,Pelvic fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,323678,DB00410,10007882,30,1575,21,988,0.771761831,0.896185172,0.493151729,1.656835356,0.875084,DB0041010007882_,0.133435398,-0.109608222,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,mupirocin,DB00410
,323892,DB09035,10043554,25,4701,59,6631,0.034161868,0.597718,0.358130824,0.970912504,0.093736071,DB0903510043554_,2.367272205,-0.514636209,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,nivolumab,DB09035
,324017,DB01240,10024264,44,5707,11,1565,0.870418234,1.096884708,0.555815236,2.360751516,0.942509353,DB0124010024264_,0.059209436,0.092474078,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,epoprostenol,DB01240
,324037,DB00381,10037867,56,29304,41,22846,0.837841275,1.064860642,0.698850081,1.634721047,0.916560521,DB0038110037867_,0.087127179,0.062843938,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,amlodipine,DB00381
,324049,DB11750,10003239,75,2425,36,1477,0.274965231,1.268807344,0.837006873,1.954815295,0.438200569,DB1175010003239_,0.825078553,0.23807736,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,clobetasol,DB11750
,324055,DB00722,10019909,25,25378,38,25994,0.131489689,0.673872017,0.38974317,1.146165709,0.257877746,DB0072210019909_,1.355269661,-0.394715072,NA,10019909,Hernia,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,324110,DB00874,10001053,32,3303,21,1955,0.775482828,0.901941607,0.502696773,1.650706571,0.877731824,DB0087410001053_,0.130414172,-0.103205499,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,guaifenesin,DB00874
,324113,DB00874,10006451,134,3201,31,1945,2.77259613993259e-07,2.626080433,1.757842425,4.033818545,4.55201058951456e-06,DB0087410006451_,12.29994153,0.965492405,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,guaifenesin,DB00874
,324149,DB01062,10013950,35,4451,16,1729,0.638582859,0.849781104,0.456688359,1.648810949,0.775774702,DB0106210013950_,0.253893133,-0.162776487,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,oxybutynin,DB01062
,324160,DB01076,10023424,34,25713,18,25565,0.036438587,1.877983337,1.030969107,3.533017282,0.098446734,DB0107610023424_,2.318239652,0.630198508,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,324209,DB00381,10062244,88,29272,26,22861,4.1662557331483e-06,2.643237328,1.689406224,4.268441283,5.03147401542858e-05,DB0038110062244_,9.897212479,0.972004426,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,324211,DB01202,10010144,130,6584,96,5622,0.312405906,1.156293026,0.879128706,1.525197495,0.47991634,DB0120210010144_,0.734143481,0.145219221,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,324294,DB01115,10064848,28,3572,30,2238,0.042689566,0.584847997,0.335669994,1.01597507,0.111087539,DB0111510064848_,2.197436749,-0.5364033,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,nifedipine,DB01115
,324316,DB00484,10046571,34,2473,18,1762,0.325788572,1.345732326,0.736214941,2.539843837,0.494282752,DB0048410046571_,0.704647554,0.296938345,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,brimonidine,DB00484
,324359,DB09153,10051398,32,7767,34,5665,0.134668056,0.68649519,0.40958042,1.148096523,0.262155145,DB0915310051398_,1.338818794,-0.37615606,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sodium chloride,DB09153
,324383,DB01015,10016807,38,9849,34,9347,0.814520645,1.060699537,0.649486373,1.738553316,0.900515044,DB0101510016807_,0.104788409,0.058928631,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,sulfamethoxazole,DB01015
,324421,DB00678,10017944,75,15524,42,10682,0.300910675,1.228723176,0.830524026,1.839505971,0.467239903,DB0067810017944_,0.760912442,0.205975562,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,324717,DB00126,10019974,67,10104,33,5912,0.467351521,1.187985225,0.770831352,1.863452805,0.633866602,DB0012610019974_,0.455916754,0.172258784,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,324719,DB06724,10019974,49,7880,17,3902,0.238261942,1.427236629,0.806419518,2.647123837,0.395873271,DB0672410019974_,0.926661143,0.355740147,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,324742,DB08910,10040829,46,16698,21,17467,0.00133116,2.291311058,1.339278682,4.044058234,0.006967798,DB0891010040829_,4.966456054,0.829124168,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,pomalidomide,DB08910
,324745,DB01065,10008531,31,4300,25,3026,0.683192605,0.872632566,0.497515089,1.544871971,0.808457376,DB0106510008531_,0.212627322,-0.136240698,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,324749,DB00316,10069889,42,65432,20,36933,0.597802215,1.185313669,0.680464955,2.131554268,0.742861971,DB0031610069889_,0.297245024,0.170007439,NA,10069889,Product adhesion issue,10077536,Product issues,Prod,acetaminophen,DB00316
,324773,DB00203,10019194,51,13827,15,8923,0.005377191,2.194051939,1.213494549,4.20465934,0.021676171,DB0020310019194_,3.831541749,0.785750035,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,324776,DB08932,10019194,73,19370,18,6579,0.276631149,1.37742626,0.813023226,2.45423419,0.440055058,DB0893210019194_,0.820855428,0.320216729,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,324780,DB00820,10037324,87,11828,20,5796,0.001316071,2.131524307,1.298024098,3.663828147,0.006898579,DB0082010037324_,4.976439858,0.756837361,NA,10037324,Pulmonary arterial pressure increased,10022891,Investigations,Inv,tadalafil,DB00820
,324782,DB00820,10061224,44,11871,21,5795,1,1.022837589,0.594703878,1.812684033,1,DB0082010061224_,0,0.022580714,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,tadalafil,DB00820
,324783,DB08932,10061224,65,19378,23,6574,0.902280789,0.958750771,0.587276953,1.618047782,0.957195726,DB0893210061224_,0.043747388,-0.042124122,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,324846,DB01098,10076308,36,8113,26,7183,0.447156861,1.225878381,0.719119933,2.116541985,0.614948888,DB0109810076308_,0.486216123,0.203657633,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,rosuvastatin,DB01098
,324900,DB00921,10060933,40,5805,32,4871,0.905717529,1.048886201,0.641411345,1.727911013,0.957861963,DB0092110060933_,0.0430516,0.04772884,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,324918,DB00182,10008479,42,5152,20,2832,0.6897723,1.1543122,0.661281648,2.079711094,0.812888491,DB0018210008479_,0.207161336,0.143504669,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,324987,DB00115,10025082,43,18382,21,10451,0.605073473,1.164185239,0.675441871,2.06634144,0.748273008,DB0011510025082_,0.289987383,0.152021477,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,325202,DB01068,10022052,61,13702,8,6832,5.31048553236161e-05,3.801513761,1.811201959,9.205181773,0.000464989,DB0106810022052_,7.673497056,1.335399346,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,325385,DB01104,10042682,57,15406,11,7275,0.00399448,2.446871195,1.269076713,5.17786953,0.017061247,DB0110410042682_,4.070945666,0.894810145,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,325400,DB00338,10019744,17,33657,58,22214,4.71218796372812e-11,0.193457248,0.105578073,0.337012032,1.62332713796322e-09,DB0033810019744_,20.238788,-1.642698734,male,10019744,Hepatitis C,10021881,Infections and infestations,Infec,omeprazole,DB00338
,325481,DB06605,10038695,113,13960,98,12935,0.678267153,1.068421904,0.806987791,1.416524509,0.805062194,DB0660510038695_,0.216835745,0.066182704,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,325552,DB01104,10043882,52,15411,9,7277,0.003501026,2.728140071,1.331208403,6.300654139,0.015331026,DB0110410043882_,4.177876684,1.003620084,female,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,sertraline,DB01104
,325562,DB09145,10067482,115,884,73,395,0.035904374,0.704072307,0.507688965,0.980908858,0.097338607,DB0914510067482_,2.329559587,-0.350874219,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,water,DB09145
,325574,DB05351,10067482,49,2674,16,1115,0.492188511,1.27689094,0.710204793,2.416337289,0.655117267,DB0535110067482_,0.422941025,0.24442817,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,dexlansoprazole,DB05351
,325602,DB11089,10023232,62,10113,49,8358,0.848710848,1.045732575,0.70651538,1.555185456,0.924592575,DB1108910023232_,0.078402098,0.044717668,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,docusate,DB11089
,325690,DB01017,10012735,52,1417,37,864,0.50501973,0.856992033,0.546418127,1.355791626,0.665985333,DB0101710012735_,0.406487631,-0.154326656,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,minocycline,DB01017
,325803,DB00581,10018884,39,2074,32,2037,0.4746651,1.196954731,0.727540161,1.982134121,0.640333196,DB0058110018884_,0.445766619,0.179780607,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,lactulose,DB00581
,325847,DB00213,10024670,37,18858,22,13399,0.597284828,1.194943919,0.686278191,2.127686482,0.742475406,DB0021310024670_,0.297765533,0.178099255,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,pantoprazole,DB00213
,325949,DB00065,10033775,87,9377,28,4929,0.023251776,1.63321169,1.054354716,2.601575441,0.069463309,DB0006510033775_,2.666956601,0.490548438,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,infliximab,DB00065
,325950,DB00433,10033775,76,7580,32,5988,0.002451658,1.876088365,1.224212259,2.9353678,0.011487983,DB0043310033775_,4.466453762,0.629188952,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,326049,DB14513,10009033,30,7147,25,3539,0.061540244,0.594222682,0.337246554,1.055461578,0.14629147,DB1451310009033_,1.922154277,-0.520501145,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium,DB14513
,326087,DB00413,10058920,39,2160,24,1183,0.690606017,0.890022897,0.519067921,1.555226953,0.813360478,DB0041310058920_,0.206580875,-0.11650809,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,pramipexole,DB00413
,326189,DB00051,10049088,51,25680,13,11407,0.077899198,1.742598963,0.93369446,3.494103423,0.174812637,DB0005110049088_,1.744040523,0.555377655,NA,10049088,Osteopenia,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,326197,DB08895,10049088,52,28062,8,6638,0.323887845,1.537532753,0.724857021,3.749730439,0.492317016,DB0889510049088_,0.708632429,0.430179023,NA,10049088,Osteopenia,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,326219,DB00153,10054112,75,7348,43,3396,0.274046145,0.806143495,0.545566263,1.204412083,0.43714911,DB0015310054112_,0.827480929,-0.215493519,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,ergocalciferol,DB00153
,326223,DB08895,10054112,93,28021,29,6617,0.203872443,0.757297413,0.493989364,1.193209299,0.353645295,DB0889510054112_,1.03946086,-0.277999218,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,tofacitinib,DB08895
,326290,DB08932,10087283,57,19386,16,6581,0.590364858,1.209354038,0.684352115,2.257831729,0.73692225,DB0893210087283_,0.305272887,0.190086364,NA,10087283,Red blood cell transfusion,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,326322,DB00196,10043071,32,5051,43,3242,0.001827612,0.477694454,0.291904452,0.774527067,0.009037489,DB0019610043071_,4.70637386,-0.738783969,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,fluconazole,DB00196
,326326,DB00126,10055798,42,10129,34,5911,0.154980508,0.720920216,0.447188468,1.169781078,0.29077859,DB0012610055798_,1.235193161,-0.327226805,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,ascorbic acid,DB00126
,326386,DB00635,10048706,60,32993,22,23772,0.006807291,1.965011543,1.187448083,3.365129946,0.026212957,DB0063510048706_,3.641501431,0.67549812,NA,10048706,Joint range of motion decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,prednisone,DB00635
,326450,DB00203,10062352,60,13818,30,8908,0.28022723,1.28930964,0.817891917,2.072328329,0.444055629,DB0020310062352_,0.811805435,0.254106912,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,326465,DB00563,10034972,52,46594,12,15336,0.311608171,1.426244729,0.751093096,2.936447826,0.479025691,DB0056310034972_,0.736001048,0.355044926,NA,10034972,Photosensitivity reaction,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,326568,DB00198,10011224,46,1229,29,974,0.407890628,1.256966154,0.766517754,2.091590044,0.577319754,DB0019810011224_,0.549359,0.228701003,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oseltamivir,DB00198
,326578,DB00422,10022000,36,3399,17,2932,0.051749701,1.826526418,0.997288836,3.475164132,0.128323184,DB0042210022000_,2.053203319,0.602416031,NA,10022000,Influenza,10021881,Infections and infestations,Infec,methylphenidate,DB00422
,326638,DB00331,10056812,42,24904,21,20731,0.057840277,1.664850903,0.963633523,2.960396366,0.139396845,DB0033110056812_,1.970430416,0.509735572,NA,10056812,Body height decreased,10022891,Investigations,Inv,metformin,DB00331
,326650,DB00193,10013911,83,19237,50,8652,0.110256604,0.746586737,0.518947529,1.083753222,0.226422504,DB0019310013911_,1.485352536,-0.292243478,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,326686,DB00333,10012218,51,3020,71,3081,0.09987739,0.732857769,0.499292218,1.069136801,0.210594994,DB0033310012218_,1.557818449,-0.310803635,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,methadone,DB00333
,326713,DB01234,10023644,98,31527,47,32841,8.39424465792022e-06,2.171972716,1.518438095,3.145581534,9.32555878416877e-05,DB0123410023644_,9.280166578,0.77563584,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,dexamethasone,DB01234
,326715,DB00373,10030041,47,1785,8,1279,2.27884439912077e-05,4.208034757,1.961277355,10.34821163,0.000223403,DB0037310030041_,8.406532766,1.436995735,female,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,timolol,DB00373
,326716,DB00869,10030041,41,1264,18,911,0.083325985,1.64130822,0.915141078,3.056098466,0.184015584,DB0086910030041_,1.692734828,0.495493619,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,dorzolamide,DB00869
,326749,DB00273,10054112,56,8425,22,2171,0.120132262,0.655956385,0.393127236,1.130881673,0.241563279,DB0027310054112_,1.420623817,-0.421660978,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,topiramate,DB00273
,326780,DB00787,10005425,42,16958,27,17221,0.070404494,1.5796499,0.950940281,2.665390566,0.162004913,DB0078710005425_,1.820128618,0.45720324,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,acyclovir,DB00787
,326789,DB00211,10022437,36,1400,20,1611,0.009802015,2.070781151,1.160926316,3.794123066,0.03501814,DB0021110022437_,3.35188906,0.727925904,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,midodrine,DB00211
,326805,DB00188,10049848,42,7844,57,8771,0.364532222,0.823932019,0.538889845,1.2507686,0.534143293,DB0018810049848_,0.627091137,-0.193667254,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,326813,DB09570,10035664,187,3714,252,3683,0.00195952,0.73590171,0.602364181,0.89778478,0.009575383,DB0957010035664_,4.648559739,-0.306658716,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ixazomib,DB09570
,326815,DB09570,10038435,29,3872,31,3904,0.89708544,0.943200647,0.547321773,1.621265467,0.956338178,DB0957010038435_,0.044643686,-0.058476244,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,ixazomib,DB09570
,326870,DB00207,10030095,44,9036,17,5438,0.144485417,1.557593484,0.871123492,2.91088959,0.276314103,DB0020710030095_,1.286217006,0.443141992,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,326910,DB01234,10043528,35,31590,28,32860,0.315346453,1.300243597,0.768285088,2.21941535,0.482950621,DB0123410043528_,0.727840864,0.262551629,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,326952,DB00425,10037884,33,12662,23,7461,0.580110834,0.845450034,0.481234999,1.509163916,0.72869727,DB0042510037884_,0.316496901,-0.167886209,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,zolpidem,DB00425
,327032,DB11365,10037844,44,1601,35,1513,0.494792356,1.187978131,0.740274318,1.919072918,0.657228907,DB1136510037844_,0.419722909,0.172252812,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sennosides,DB11365
,327077,DB08908,10013887,46,10627,15,3264,0.879669384,0.9419009,0.515602999,1.818853634,0.949457398,DB0890810013887_,0.051864617,-0.059855212,NA,10013887,Dysarthria,10029205,Nervous system disorders,Nerv,dimethyl fumarate,DB08908
,327082,DB01015,10014387,27,9860,39,9342,0.108314532,0.655955745,0.385812551,1.100198232,0.223530451,DB0101510014387_,1.498207626,-0.421661955,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,327093,DB00381,10047302,21,29339,31,22856,0.024894341,0.527746121,0.288145524,0.94853983,0.073261481,DB0038110047302_,2.6137203,-0.639139942,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,amlodipine,DB00381
,327102,DB00678,10022093,67,15532,8,10716,1.12487285542669e-08,5.777729998,2.768419443,13.93027599,2.50464066115125e-07,DB0067810022093_,15.19995038,1.754010872,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,327189,DB01012,10005702,51,10581,30,8655,0.17901765,1.39053305,0.868068084,2.263432472,0.322679852,DB0101210005702_,1.131094619,0.329687163,NA,10005702,Blood parathyroid hormone decreased,10022891,Investigations,Inv,cinacalcet,DB01012
,327293,DB00820,10003662,47,11868,22,5794,1,1.042974714,0.615502731,1.819165095,1,DB0082010003662_,0,0.042076932,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,tadalafil,DB00820
,327313,DB01377,10006451,45,3751,15,2655,0.011712829,2.123194869,1.158747505,4.109741925,0.040376617,DB0137710006451_,3.209504445,0.752921968,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,magnesium oxide,DB01377
,327343,DB00338,10029446,25,33649,30,22242,0.027732021,0.550856641,0.310526495,0.96920055,0.079639043,DB0033810029446_,2.530250817,-0.596280684,NA,10029446,Nocturia,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,327460,DB00230,10007739,116,19558,35,8616,0.051218561,1.460074284,0.991909957,2.198170793,0.127336701,DB0023010007739_,2.060920508,0.378487314,NA,10007739,Cataract,10015919,Eye disorders,Eye,pregabalin,DB00230
,327597,DB00343,10038153,32,8704,22,5073,0.573220361,0.847777675,0.476921511,1.53314726,0.723180167,DB0034310038153_,0.324096894,-0.165136853,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,diltiazem,DB00343
,327714,DB00996,10012680,38,38915,27,22398,0.439767317,0.81006469,0.481602143,1.379993966,0.608095319,DB0099610012680_,0.497423634,-0.21064117,NA,10012680,Diabetic neuropathy,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,327882,DB00745,10010305,36,2541,14,1069,0.8770529,1.081777313,0.56662741,2.180623706,0.947566093,DB0074510010305_,0.053858589,0.078605349,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,modafinil,DB00745
,327996,DB01268,10008531,26,2117,36,3094,0.896680631,1.05550091,0.609996836,1.803466392,0.956301489,DB0126810008531_,0.044682051,0.05401545,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,327997,DB00335,10011781,43,8423,7,5458,0.000126337,3.980175315,1.773411937,10.49682027,0.000974402,DB0033510011781_,6.933687003,1.381325867,female,10011781,Cystitis,10021881,Infections and infestations,Infec,atenolol,DB00335
,328040,DB00005,10073311,72,128010,17,42402,0.222415517,1.402871739,0.818342355,2.539759346,0.376493551,DB0000510073311_,0.976854362,0.338521378,NA,10073311,Occupational exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,328042,DB00374,10042209,65,17651,10,5714,0.022273059,2.104008172,1.073276428,4.596748618,0.067234838,DB0037410042209_,2.699563738,0.743844179,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,treprostinil,DB00374
,328046,DB01611,10031161,124,11789,17,2344,0.171457553,1.450247734,0.867984528,2.574317072,0.312806649,DB0161110031161_,1.162170015,0.371734393,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,328166,DB08882,10035664,30,967,22,971,0.325377393,1.369056533,0.757637925,2.509931976,0.493795888,DB0888210035664_,0.705633029,0.314121841,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,linagliptin,DB08882
,328175,DB08932,10019660,34,19409,21,6576,0.041954295,0.5485817,0.309073874,0.995398623,0.109611519,DB0893210019660_,2.210812813,-0.600419058,NA,10019660,Hepatic encephalopathy,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,328188,DB00722,10075192,19,25384,41,25991,0.006416492,0.474504922,0.260029608,0.836528106,0.024975196,DB0072210075192_,3.689872115,-0.745483288,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,lisinopril,DB00722
,328190,DB00046,10076309,41,5418,26,4666,0.268486222,1.358008679,0.809664491,2.316246778,0.430942554,DB0004610076309_,0.841780483,0.30601942,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin lispro,DB00046
,328285,DB05679,10022000,42,6889,15,4894,0.021547579,1.989024793,1.07916971,3.865999128,0.065575793,DB0567910022000_,2.724548666,0.687644465,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ustekinumab,DB05679
,328288,DB05679,10037087,117,6814,52,4857,0.004541629,1.6037295,1.144760416,2.27324012,0.01891266,DB0567910037087_,3.967923729,0.472331854,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ustekinumab,DB05679
,328292,DB00678,10037162,79,15520,40,10684,0.134299088,1.35957785,0.917352067,2.043411872,0.261717936,DB0067810037162_,1.340487934,0.307174247,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,losartan,DB00678
,328316,DB05679,10046735,87,6844,31,4878,0.000674827,2.00015334,1.311227836,3.124467703,0.003973531,DB0567910046735_,5.52810028,0.693223848,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,ustekinumab,DB05679
,328327,DB00051,10067484,108,25623,26,11394,0.003577527,1.847099622,1.194022688,2.955675876,0.015593286,DB0005110067484_,4.16091486,0.613616637,NA,10067484,Adverse reaction,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,328352,DB00443,10003239,58,2088,30,1160,0.821929477,1.074058658,0.675396891,1.739671889,0.905181368,DB0044310003239_,0.099619949,0.071444611,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,betamethasone,DB00443
,328371,DB00476,10048010,217,17040,62,6115,0.116455196,1.25599083,0.941566251,1.696370073,0.23580809,DB0047610048010_,1.444736983,0.227924767,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,328404,DB01234,10060933,79,31546,61,32827,0.090276355,1.34765997,0.952372357,1.914944661,0.195696178,DB0123410060933_,1.631191937,0.298369733,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,328488,DB08907,10061180,114,4139,81,3829,0.081439091,1.301951757,0.967176432,1.759220746,0.180769661,DB0890710061180_,1.710531647,0.26386449,NA,10061180,Genital infection fungal,10021881,Infections and infestations,Infec,canagliflozin,DB08907
,328497,DB00921,10033295,98,5747,187,4716,8.01578681105976e-12,0.430079006,0.332270852,0.55385917,3.11218547014336e-10,DB0092110033295_,21.89052573,-0.843786353,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,buprenorphine,DB00921
,328518,DB01275,10047899,48,3931,43,3306,0.832445217,0.938829629,0.60731398,1.455213485,0.912651618,DB0127510047899_,0.091401051,-0.063121255,NA,10047899,Weight increased,10022891,Investigations,Inv,hydralazine,DB01275
,328668,DB00273,10022061,67,8414,6,2187,0.008099473,2.902321736,1.263369084,8.200008523,0.030091115,DB0027310022061_,3.503525321,1.065511015,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,328670,DB00273,10022086,122,8359,11,2182,0.000201137,2.894970397,1.558596431,5.963061464,0.00144767,DB0027310022086_,6.537799617,1.062974885,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,328687,DB00273,10053425,51,8430,7,2186,0.140801538,1.889143522,0.852048603,4.94175427,0.270964485,DB0027310053425_,1.305767519,0.636123563,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,328743,DB06724,10013781,59,7870,7,3912,3.36101198577071e-05,4.188831171,1.908732957,10.87948356,0.000313555,DB0672410013781_,8.067534883,1.432421738,female,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,328831,DB00395,10010144,234,1950,78,658,1,1.012307597,0.767745094,1.345781827,1,DB0039510010144_,0,0.012232474,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,carisoprodol,DB00395
,328832,DB00402,10010144,86,1266,54,642,0.267172538,0.80772094,0.560098366,1.173087904,0.429452999,DB0040210010144_,0.845242975,-0.213538651,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,eszopiclone,DB00402
,328847,DB01275,10018378,55,3924,31,3318,0.081188845,1.500112732,0.946431368,2.416658008,0.180400592,DB0127510018378_,1.71257539,0.40554026,NA,10018378,Glomerulonephritis rapidly progressive,10038359,Renal and urinary disorders,Renal,hydralazine,DB01275
,328877,DB00635,10018100,38,33015,17,23777,0.102949991,1.609815263,0.886651473,3.042439971,0.215397637,DB0063510018100_,1.535269485,0.476119429,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,328990,DB00635,10043089,32,33021,36,23758,0.066054817,0.639557959,0.384418552,1.0595984,0.154251143,DB0063510043089_,1.869173204,-0.44697803,NA,10043089,Tachypnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,329236,DB00016,10016322,35,2727,31,2259,0.804475628,0.935300283,0.558199298,1.573946948,0.894353284,DB0001610016322_,0.111654409,-0.066887643,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,329237,DB00136,10016322,38,2054,15,1667,0.017654387,2.055621191,1.100131349,4.036934159,0.056037381,DB0013610016322_,2.881736295,0.720578085,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,calcitriol,DB00136
,329382,DB01263,10013710,34,590,36,829,0.265213863,1.326751064,0.795214093,2.209605389,0.427179754,DB0126310013710_,0.850550386,0.282733145,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,posaconazole,DB01263
,329391,DB01263,10053762,41,583,72,793,0.234195332,0.774692673,0.506757237,1.171151096,0.391057034,DB0126310053762_,0.938901862,-0.255288879,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,posaconazole,DB01263
,329407,DB00115,10003285,101,18324,32,10440,0.003639859,1.798221761,1.196727346,2.768880027,0.015809912,DB0011510003285_,4.147118193,0.586798266,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,329411,DB08910,10044390,23,16721,34,17454,0.232710633,0.706134766,0.397009515,1.234821745,0.389196003,DB0891010044390_,0.943672197,-0.347949174,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,329446,DB08868,10028810,169,9033,36,2475,0.197501106,1.286223834,0.890457089,1.903599872,0.345995506,DB0886810028810_,1.061329493,0.251710665,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,fingolimod,DB08868
,329558,DB00177,10047942,59,4741,33,2817,0.828834159,1.062316889,0.680469291,1.684021164,0.910059145,DB0017710047942_,0.094245687,0.060452267,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,valsartan,DB00177
,329559,DB00758,10047942,67,8233,73,10001,0.551105934,1.114895836,0.78704364,1.577174748,0.705163416,DB0075810047942_,0.349325707,0.10876098,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,clopidogrel,DB00758
,329583,DB01118,10040070,25,3038,33,4676,0.590799397,1.166009426,0.663320285,2.025995866,0.737333487,DB0111810040070_,0.304714996,0.153587172,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,amiodarone,DB01118
,329608,DB00928,10035664,53,782,95,1191,0.383771428,0.849763296,0.588053165,1.217266006,0.553752476,DB0092810035664_,0.591037487,-0.162797444,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,azacitidine,DB00928
,329643,DB00760,10040070,23,757,46,969,0.106773263,0.640180913,0.366893276,1.089157275,0.221283231,DB0076010040070_,1.508311811,-0.446004467,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,meropenem,DB00760
,329673,DB00996,10016275,35,38918,16,22409,0.471435254,1.259588385,0.678832296,2.437770847,0.637669961,DB0099610016275_,0.449934433,0.230784989,NA,10016275,Fear,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,329735,DB00404,10073302,31,19861,22,9840,0.192406273,0.698112771,0.391167887,1.266196643,0.339650697,DB0040410073302_,1.079837551,-0.359374626,NA,10073302,Exposure via ingestion,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,329736,DB00425,10073302,42,12653,19,7465,0.356421833,1.304146755,0.7413233,2.375982442,0.526116016,DB0042510073302_,0.642233528,0.265548999,NA,10073302,Exposure via ingestion,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,329793,DB08932,10012442,109,19334,16,6581,0.000876763,2.318946045,1.364278518,4.203202507,0.0049449,DB0893210012442_,5.309398443,0.841112792,NA,10012442,Dermatitis contact,10040785,Skin and subcutaneous tissue disorders,Skin,macitentan,DB08932
,329798,DB00904,10033433,84,22985,22,14434,0.000123841,2.39766428,1.484195873,4.029924168,0.00095768,DB0090410033433_,6.950996559,0.874495047,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,329898,DB08868,10046306,126,9076,32,2479,0.770268812,1.075459056,0.722646465,1.643214697,0.874164144,DB0886810046306_,0.134487113,0.072747599,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,fingolimod,DB08868
,329936,DB01234,10061599,46,31579,16,32872,6.40803679825995e-05,2.992735649,1.662606368,5.665267753,0.000544305,DB0123410061599_,7.516000421,1.096187902,female,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,329946,DB00273,10042464,50,8431,6,2187,0.069157824,2.161490564,0.924698171,6.177484824,0.159814796,DB0027310042464_,1.83373966,0.770798059,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,topiramate,DB00273
,329958,DB00537,10024855,33,7524,19,4279,1,0.987762659,0.544680826,1.841102752,1,DB0053710024855_,0,-0.012312834,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,330047,DB01029,10037087,43,1297,9,892,0.000492181,3.284391904,1.569134707,7.702601802,0.003054055,DB0102910037087_,5.79128519,1.189181522,female,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,irbesartan,DB01029
,330071,DB00635,10058806,45,33008,34,23760,0.82071339,0.952738815,0.596597905,1.534174338,0.904519726,DB0063510058806_,0.100351166,-0.048414479,NA,10058806,Mycobacterium avium complex infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,330156,DB00425,10029216,33,12662,20,7464,1,0.972626523,0.541380497,1.790037887,1,DB0042510029216_,0,-0.027755111,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,330212,DB06282,10003549,35,1505,17,516,0.260785545,0.706010288,0.381247558,1.356040121,0.422281507,DB0628210003549_,0.862083109,-0.34812547,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,levocetirizine,DB06282
,330236,DB01377,10041349,42,3754,31,2639,0.90495498,0.952462004,0.5829426,1.571625102,0.957667115,DB0137710041349_,0.043255041,-0.048705064,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,magnesium oxide,DB01377
,330281,DB00669,10010305,46,6331,6,1091,0.693659027,1.321125294,0.560966424,3.794285611,0.815581461,DB0066910010305_,0.203853972,0.278483869,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,sumatriptan,DB00669
,330515,DB01047,10016256,31,756,20,460,0.883231249,0.943165992,0.513817036,1.768115187,0.951169726,DB0104710016256_,0.050062761,-0.058512986,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,fluocinonide,DB01047
,330540,DB00287,10003549,32,1369,18,799,1,1.037563332,0.560878276,1.976906894,1,DB0028710003549_,0,0.036875014,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,travoprost,DB00287
,330637,DB08877,10000087,34,3255,25,3204,0.296613646,1.338627419,0.773497157,2.346233729,0.462434706,DB0887710000087_,0.771249907,0.291644775,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ruxolitinib,DB08877
,330641,DB01273,10033371,64,1976,13,1262,4.39598245006858e-05,3.143273056,1.705377661,6.247989272,0.000396189,DB0127310033371_,7.833620254,1.145264631,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,varenicline,DB01273
,330648,DB08889,10037844,49,3116,64,3821,0.775417825,0.938842214,0.63163107,1.388095969,0.877677147,DB0888910037844_,0.130476468,-0.06310785,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,carfilzomib,DB08889
,330673,DB00656,10061623,57,11956,40,6579,0.243259687,0.784159047,0.513669906,1.207255837,0.401607433,DB0065610061623_,0.912280202,-0.243143413,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,330674,DB01137,10061623,29,7743,32,5561,0.117768212,0.650901078,0.379399774,1.112292893,0.237847652,DB0113710061623_,1.436124926,-0.429397602,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,330762,DB00814,10047942,69,8218,27,3388,0.910350094,1.053563097,0.664935416,1.713663875,0.959579421,DB0081410047942_,0.041260194,0.052177845,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,meloxicam,DB00814
,330780,DB01592,10015090,43,6233,22,3045,0.894730086,0.954856918,0.55752834,1.679351445,0.955976233,DB0159210015090_,0.045022227,-0.046193773,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iron,DB01592
,330821,DB09045,10012735,131,2218,111,1613,0.254768769,0.858299859,0.655829685,1.124823383,0.415502987,DB0904510012735_,0.878265475,-0.152801754,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dulaglutide,DB09045
,330822,DB09045,10028813,353,1996,158,1566,1.87951657428015e-08,1.752626813,1.431424454,2.152873512,3.9569958474132e-07,DB0904510028813_,14.74261054,0.561115698,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dulaglutide,DB09045
,330824,DB09045,10047700,122,2227,73,1651,0.159109576,1.238913783,0.912653974,1.69145059,0.296304879,DB0904510047700_,1.216366359,0.214235015,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dulaglutide,DB09045
,330826,DB09045,10061428,41,2308,29,1695,0.903555884,1.038287793,0.626917266,1.74000758,0.957409002,DB0904510061428_,0.043524599,0.037573004,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,dulaglutide,DB09045
,330850,DB00051,10066901,644,25087,154,11266,2.21407875592509e-13,1.877930938,1.570453863,2.256970385,1.08677983379068e-11,DB0005110066901_,25.24521698,0.630170606,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,330855,DB05679,10066901,75,6856,51,4858,0.856092689,1.042025559,0.718958961,1.520781,0.930627756,DB0567910066901_,0.071895914,0.041166472,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,330937,DB00927,10028836,47,7450,12,5004,0.001932088,2.630545354,1.372263398,5.453254711,0.009465973,DB0092710028836_,4.660051743,0.967191184,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,famotidine,DB00927
,331088,DB00581,10038695,41,2072,29,2040,0.186226217,1.391843762,0.840586789,2.331950694,0.331726492,DB0058110038695_,1.103444468,0.330629316,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lactulose,DB00581
,331184,DB00959,10074170,35,8043,20,4982,0.889589871,1.083991088,0.607899559,1.984032335,0.954130238,DB0095910074170_,0.046955099,0.080649681,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,331343,DB00953,10016256,100,1597,19,213,0.188904456,0.702120277,0.416573814,1.240348347,0.335168493,DB0095310016256_,1.09312191,-0.353650555,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,rizatriptan,DB00953
,331440,DB00480,10017822,34,67394,35,67627,1,0.974782637,0.58976088,1.609533448,1,DB0048010017822_,0,-0.025540769,NA,10017822,Gastric ulcer,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,331635,DB05676,10040744,55,47074,32,25297,0.736345035,0.923637967,0.586682353,1.476406541,0.847745865,DB0567610040744_,0.165174375,-0.079435095,NA,10040744,Sinus headache,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,331675,DB01168,10028813,170,511,177,654,0.097145746,1.229051396,0.959474211,1.574252654,0.20652795,DB0116810028813_,1.577319523,0.206242649,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,procarbazine,DB01168
,331677,DB01168,10035528,39,642,39,792,0.413671036,1.233466566,0.760746831,2.000071343,0.583032763,DB0116810035528_,0.539511898,0.209828551,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,procarbazine,DB01168
,331678,DB01168,10047700,46,635,45,786,0.279480663,1.26509575,0.808770389,1.97997866,0.443313573,DB0116810047700_,0.81347792,0.235147811,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,procarbazine,DB01168
,331708,DB01592,10017885,50,6226,15,3052,0.111164533,1.633929692,0.901028801,3.138197009,0.227833118,DB0159210017885_,1.479141855,0.490987967,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,331728,DB00264,10066274,41,29566,24,24868,0.171520386,1.436868945,0.847575012,2.4867963,0.312823575,DB0026410066274_,1.162115907,0.362466403,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,metoprolol,DB00264
,331729,DB00316,10066274,60,65414,40,36913,0.406867222,0.846456158,0.557904473,1.29655759,0.576383353,DB0031610066274_,0.550982296,-0.166696871,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,acetaminophen,DB00316
,331732,DB00451,10066274,43,47228,14,15405,1,1.001849711,0.537473374,1.983323625,1,DB0045110066274_,0,0.001848003,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,levothyroxine,DB00451
,331734,DB00695,10066274,34,28015,30,20498,0.451021736,0.829244016,0.492308113,1.403281366,0.618683241,DB0069510066274_,0.480161863,-0.187240818,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,furosemide,DB00695
,331736,DB00996,10066274,40,38913,16,22409,0.266607815,1.439677599,0.788208494,2.754459998,0.428794371,DB0099610066274_,0.846777796,0.364419199,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,gabapentin,DB00996
,331777,DB00514,10038669,40,2126,29,1507,1,0.977712151,0.588215956,1.643199823,1,DB0051410038669_,0,-0.022539977,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dextromethorphan,DB00514
,331778,DB00921,10038669,35,5810,29,4874,1,1.012463235,0.600235266,1.719896524,1,DB0092110038669_,0,0.012386208,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,buprenorphine,DB00921
,331779,DB00921,10070863,164,5681,200,4703,0.000324197,0.678867387,0.546764773,0.841921769,0.002149726,DB0092110070863_,6.142414917,-0.387329477,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,buprenorphine,DB00921
,331897,DB01075,10005191,57,19891,31,11066,1,1.022933033,0.648962102,1.640304496,1,DB0107510005191_,0,0.022674023,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,diphenhydramine,DB01075
,331900,DB14500,10005191,46,7763,17,4056,0.234385143,1.413726271,0.793952736,2.633945086,0.391286979,DB1450010005191_,0.938314027,0.346228964,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,potassium,DB14500
,331918,DB14500,10039101,59,7750,7,4066,1.98274258935116e-05,4.421162342,2.014639273,11.4854893,0.00019835,DB1450010039101_,8.525478822,1.486402635,female,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,potassium,DB14500
,331919,DB00028,10040844,31,13427,27,5588,0.00583306,0.477839694,0.275693138,0.832983341,0.023144689,DB0002810040844_,3.765989946,-0.738479972,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,human immunoglobulin g,DB00028
,331948,DB05259,10040831,49,11221,8,2720,0.401070133,1.484669315,0.696254684,3.634369216,0.570893991,DB0525910040831_,0.560551741,0.395192064,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,glatiramer,DB05259
,332018,DB00169,10040026,46,38645,19,18156,0.691465631,1.137437933,0.653237258,2.056383085,0.813971701,DB0016910040026_,0.205829679,0.128778306,NA,10040026,Sensory disturbance,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,332035,DB08868,10047943,43,9159,12,2499,1,0.977700159,0.505548051,2.039968906,1,DB0886810047943_,0,-0.022552242,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,fingolimod,DB08868
,332095,DB00472,10060800,41,10718,10,4302,0.165866451,1.645645862,0.809762224,3.68745653,0.305308099,DB0047210060800_,1.186433851,0.498132929,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,fluoxetine,DB00472
,332157,DB01234,10040984,59,31566,55,32833,0.574874197,1.1157821,0.759267229,1.641984711,0.724501631,DB0123410040984_,0.322271267,0.109555594,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,332159,DB08880,10020751,43,3295,7,802,0.374237543,1.495025996,0.663511612,3.953913495,0.544062759,DB0888010020751_,0.608690674,0.402143596,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,teriflunomide,DB08880
,332165,DB08820,10021789,255,4146,152,3393,0.002503127,1.372882244,1.112719936,1.69839166,0.011670958,DB0882010021789_,4.450651743,0.316912357,NA,10021789,Infection,10021881,Infections and infestations,Infec,ivacaftor,DB08820
,332381,DB06403,10049848,55,21416,14,6647,0.572690929,1.219319312,0.668416952,2.376005316,0.722737712,DB0640310049848_,0.3247089,0.198292762,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,332486,DB08820,10074549,74,4327,70,3475,0.352428832,0.849007939,0.602026636,1.198335957,0.522171971,DB0882010074549_,0.649758298,-0.163686742,NA,10074549,Cystic fibrosis respiratory infection suppression,10042613,Surgical and medical procedures,Surg,ivacaftor,DB08820
,332604,DB00836,10031009,35,5500,16,4059,0.119483101,1.614294365,0.868839443,3.128224497,0.240549426,DB0083610031009_,1.424829697,0.478897935,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,332667,DB00448,10022000,70,5075,27,3097,0.04521123,1.582036915,0.999101522,2.572142152,0.115990094,DB0044810022000_,2.154250488,0.458713203,NA,10022000,Influenza,10021881,Infections and infestations,Infec,lansoprazole,DB00448
,332795,DB01060,10069339,104,8483,149,4932,2.37377346844633e-12,0.405833752,0.312041496,0.526224575,1.00717733039728e-10,DB0106010069339_,23.01869923,-0.901811681,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,amoxicillin,DB01060
,332884,DB00341,10042209,73,11332,8,5060,1.01855260793374e-05,4.074664574,1.960276872,9.799699209,0.000110334,DB0034110042209_,9.111994313,1.40478843,female,10042209,Stress,10037175,Psychiatric disorders,Psych,cetirizine,DB00341
,332888,DB08895,10042209,111,28003,14,6632,0.022377878,1.877685998,1.072410472,3.548717094,0.067466023,DB0889510042209_,2.696131166,0.630040166,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,tofacitinib,DB08895
,332900,DB00051,10022075,46,25685,11,11409,0.062663141,1.857491298,0.94731058,3.978621125,0.148420972,DB0005110022075_,1.907702638,0.619226813,NA,10022075,Injection site induration,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,332922,DB06655,10037087,44,3644,17,2102,0.181940639,1.492896941,0.833431834,2.794488779,0.326321473,DB0665510037087_,1.11987227,0.400718488,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,liraglutide,DB06655
,333037,DB00480,10024384,81,67347,88,67574,0.644418847,0.923581633,0.674299803,1.263623594,0.780476932,DB0048010024384_,0.247850094,-0.079496088,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,lenalidomide,DB00480
,333059,DB00012,10011224,49,1597,46,1267,0.462819388,0.845154548,0.549518169,1.30179824,0.630044157,DB0001210011224_,0.461965371,-0.168235771,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,darbepoetin alfa,DB00012
,333163,DB00641,10076308,66,14058,58,12417,1,1.005099518,0.694924805,1.457082148,1,DB0064110076308_,0,0.005086559,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,333164,DB00678,10076308,93,15506,48,10676,0.121618171,1.333968672,0.930947372,1.933150713,0.243731662,DB0067810076308_,1.411687407,0.288158463,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,333213,DB00281,10021015,48,11410,19,5652,0.438272279,1.251369859,0.721193189,2.256627917,0.606698276,DB0028110021015_,0.499723686,0.224238839,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,lidocaine,DB00281
,333364,DB00275,10017885,47,2013,27,1210,0.903792039,1.046336472,0.634600643,1.757074816,0.957427658,DB0027510017885_,0.043505114,0.045294989,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,olmesartan,DB00275
,333426,DB00688,10001760,85,6405,16,5362,4.96931601958767e-10,4.446871499,2.582994356,8.141825953,1.4586093978209e-08,DB0068810001760_,18.04319723,1.492200815,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,mycophenolate mofetil,DB00688
,333428,DB00864,10001760,85,6784,23,8369,8.40638233655852e-13,4.559010871,2.844174823,7.582771858,3.80968551235243e-11,DB0086410001760_,23.99088938,1.517105686,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,tacrolimus,DB00864
,333514,DB00787,10041541,32,16968,22,17226,0.174129844,1.476637344,0.831392411,2.668372165,0.316331671,DB0078710041541_,1.150964024,0.389767438,NA,10041541,Spinal compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,333562,DB00381,10056819,96,29264,43,22844,0.002020671,1.742746749,1.203724245,2.55987721,0.00980765,DB0038110056819_,4.624592601,0.55546246,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,amlodipine,DB00381
,333577,DB00334,10011906,127,2722,103,2709,0.138660102,1.227074328,0.933405749,1.61622003,0.267873054,DB0033410011906_,1.317242088,0.204632741,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,olanzapine,DB00334
,333634,DB00230,10064848,83,19591,35,8616,0.920284033,1.042922551,0.694052587,1.597019415,0.964711792,DB0023010064848_,0.035925884,0.042026917,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,pregabalin,DB00230
,333639,DB01068,10064848,61,13702,21,6819,0.159190084,1.445572862,0.866966576,2.501608431,0.296391808,DB0106810064848_,1.216073023,0.368505687,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,clonazepam,DB01068
,333666,DB08868,10025327,153,9049,53,2458,0.144858723,0.784163392,0.568303582,1.096638598,0.276836669,DB0886810025327_,1.28432759,-0.243137872,NA,10025327,Lymphopenia,10005329,Blood and lymphatic system disorders,Blood,fingolimod,DB08868
,333896,DB08931,10044565,75,6502,28,2418,1,0.996122477,0.635751049,1.60156577,1,DB0893110044565_,0,-0.00388506,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,333939,DB01033,10008531,26,1156,31,1273,0.790027486,0.923595517,0.523311577,1.618239244,0.886199614,DB0103310008531_,0.120813056,-0.079481055,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,mercaptopurine,DB01033
,333965,DB00620,10021143,34,4794,16,3116,0.312450929,1.381151501,0.740346615,2.684600729,0.479934902,DB0062010021143_,0.734104805,0.322917572,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,triamcinolone,DB00620
,334064,DB00503,10070863,20,693,42,971,0.150291359,0.667367208,0.367745843,1.174224284,0.28437458,DB0050310070863_,1.257462966,-0.404414848,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,ritonavir,DB00503
,334147,DB00080,10069339,29,611,53,860,0.300333424,0.770284234,0.466409261,1.250040637,0.466495143,DB0008010069339_,0.76250767,-0.260995697,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,daptomycin,DB00080
,334212,DB01212,10007515,57,1962,44,1897,0.313371063,1.252463481,0.825868038,1.91042695,0.480908945,DB0121210007515_,0.73207733,0.225112397,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,ceftriaxone,DB01212
,334214,DB00370,10018884,38,4503,33,3630,0.810824444,0.928283191,0.565609885,1.530600042,0.898226748,DB0037010018884_,0.107332739,-0.07441843,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,mirtazapine,DB00370
,334270,DB01024,10021789,37,2174,32,2088,0.71646522,1.110475979,0.670280061,1.848995352,0.83234794,DB0102410021789_,0.183504729,0.104788733,NA,10021789,Infection,10021881,Infections and infestations,Infec,mycophenolic acid,DB01024
,334325,DB01592,10035598,45,6231,17,3050,0.416819569,1.295717506,0.725750729,2.418898698,0.586013177,DB0159210035598_,0.534413003,0.2590646,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iron,DB01592
,334328,DB00115,10035742,36,18389,24,10448,0.591172631,0.852260141,0.494319748,1.494124206,0.737597788,DB0011510035742_,0.304356605,-0.159863469,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyanocobalamin,DB00115
,334358,DB00836,10061024,33,5502,20,4055,0.577727826,1.216032971,0.676278057,2.239819095,0.72663473,DB0083610061024_,0.319331363,0.195593898,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,loperamide,DB00836
,334429,DB00264,10028606,33,29574,21,24871,0.341214394,1.321523855,0.741918616,2.404201746,0.510375027,DB0026410028606_,0.672609476,0.278785507,NA,10028606,Myocarditis,10007541,Cardiac disorders,Card,metoprolol,DB00264
,334482,DB01137,10066371,47,7725,28,5565,0.481904981,1.209200392,0.740659779,2.0079246,0.646365533,DB0113710066371_,0.436390095,0.189959308,NA,10066371,Tendon pain,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,334507,DB08932,10020096,73,19370,10,6587,0.004975266,2.482529945,1.275007925,5.39628567,0.020379461,DB0893210020096_,3.89322772,0.909278179,NA,10020096,Hip arthroplasty,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,334520,DB01073,10038435,14,1051,44,1606,0.02013655,0.486321922,0.244855317,0.909659142,0.062097638,DB0107310038435_,2.779047327,-0.720884483,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,fludarabine,DB01073
,334567,DB01046,10033371,49,836,6,322,0.004725111,3.143103576,1.327363136,9.067018135,0.019545132,DB0104610033371_,3.935029044,1.145210712,female,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,lubiprostone,DB01046
,334584,DB00563,10019708,119,46527,52,15296,0.091800798,0.752347811,0.538503717,1.063806822,0.198126609,DB0056310019708_,1.618849012,-0.284556548,NA,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,methotrexate,DB00563
,334638,DB01069,10017885,49,6651,17,2378,1,1.030570715,0.581806964,1.912653377,1,DB0106910017885_,0,0.030112741,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,promethazine,DB01069
,334690,DB00126,10061623,82,10089,44,5901,0.711046212,1.090035951,0.74566403,1.612330554,0.827716992,DB0012610061623_,0.18908398,0.086210678,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,334692,DB00285,10061623,39,10912,30,3688,0.001188441,0.439393556,0.26559223,0.733563281,0.006356297,DB0028510061623_,5.058309332,-0.822359784,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,334816,DB08904,10003549,76,11534,16,3543,0.216249477,1.459042242,0.841919401,2.684444188,0.368906898,DB0890410003549_,0.997210975,0.377780222,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,334821,DB08904,10016256,433,11177,115,3444,0.181767651,1.160172995,0.938916223,1.442863774,0.326151169,DB0890410016256_,1.120394295,0.148569127,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,334823,DB00993,10021789,47,3202,24,1595,0.89974526,0.975483314,0.582150592,1.674365947,0.956571579,DB0099310021789_,0.044399659,-0.024822224,NA,10021789,Infection,10021881,Infections and infestations,Infec,azathioprine,DB00993
,334827,DB01432,10035664,49,1242,22,648,0.611968999,1.161992534,0.68241281,2.037046941,0.753883167,DB0143210035664_,0.282517874,0.150136234,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cholestyramine,DB01432
,334847,DB00563,10062016,64,46582,17,15331,0.519580319,1.239023478,0.716670089,2.257472679,0.678751984,DB0056310062016_,0.387499485,0.214323551,NA,10062016,Immunosuppression,10021428,Immune system disorders,Immun,methotrexate,DB00563
,334848,DB00635,10062016,60,32993,43,23751,1,1.004483671,0.667517615,1.522954416,1,DB0063510062016_,0,0.004473649,NA,10062016,Immunosuppression,10021428,Immune system disorders,Immun,prednisone,DB00635
,334861,DB00186,10012267,40,16861,20,9988,0.594193722,1.184775605,0.675992207,2.140419517,0.740162623,DB0018610012267_,0.300885356,0.169553394,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,lorazepam,DB00186
,334928,DB00997,10074170,12,5319,40,3474,7.30606508586244e-08,0.195974127,0.093446191,0.381716286,1.36295188631579e-06,DB0099710074170_,13.50585771,-1.629772633,male,10074170,Candida infection,10021881,Infections and infestations,Infec,doxorubicin,DB00997
,334937,DB01104,10023232,104,15359,26,7260,0.002514172,1.890701304,1.219299516,3.031333726,0.011712007,DB0110410023232_,4.447140738,0.636947821,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,335044,DB00480,10039101,296,67132,212,67450,0.000182695,1.402830606,1.17166187,1.681942053,0.001336337,DB0048010039101_,6.617822742,0.338492057,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,335055,DB00761,10044034,48,15259,14,8611,0.033150011,1.934771156,1.048483366,3.80230491,0.091624399,DB0076110044034_,2.390057679,0.659989054,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,335183,DB00660,10013709,53,1204,15,352,1,1.032996082,0.565293155,1.998132919,1,DB0066010013709_,0,0.032463398,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,metaxalone,DB00660
,335222,DB00924,10006002,55,10107,19,4232,0.524415396,1.212054365,0.707147471,2.165520198,0.682557994,DB0092410006002_,0.381907783,0.192316742,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,335313,DB00704,10010305,35,4321,35,5159,0.472159715,1.193911134,0.724245709,1.96815688,0.638214445,DB0070410010305_,0.449080932,0.177234585,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,335315,DB00704,10024264,21,4335,45,5149,0.025483159,0.554328647,0.313127701,0.951778681,0.074574131,DB0070410024264_,2.595961606,-0.589997543,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,naltrexone,DB00704
,335333,DB01068,10011781,45,13718,11,6829,0.032645078,2.036446404,1.036221536,4.368803119,0.090519107,DB0106810011781_,2.402194328,0.71120633,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,clonazepam,DB01068
,335358,DB00423,10037087,41,2426,17,1023,1,1.01700023,0.562098194,1.918689099,1,DB0042310037087_,0,0.016857343,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,methocarbamol,DB00423
,335375,DB09035,10005483,26,4700,51,6639,0.201604306,0.720145753,0.430319437,1.178754195,0.351008093,DB0903510005483_,1.046945998,-0.328301652,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,nivolumab,DB09035
,335402,DB01224,10022004,41,8067,10,5907,0.000922643,3.001939684,1.4773115,6.726405371,0.005156636,DB0122410022004_,5.267470806,1.099258641,female,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,335419,DB00203,10005619,40,13838,15,8923,0.073326863,1.719475735,0.928681289,3.352622432,0.167059223,DB0020310005619_,1.789406899,0.542019439,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,sildenafil,DB00203
,335470,DB09140,10035528,48,3693,10,1788,0.011124968,2.323668118,1.157373707,5.163782221,0.038751628,DB0914010035528_,3.250582523,0.843147023,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,oxygen,DB09140
,335471,DB00535,10035664,76,1128,64,582,0.007283825,0.612848084,0.426865965,0.882136071,0.027619061,DB0053510035664_,3.589249125,-0.489638197,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cefdinir,DB00535
,335477,DB01137,10068319,53,7719,24,5569,0.063578512,1.593182511,0.965075353,2.701871689,0.14992699,DB0113710068319_,1.897606836,0.465733595,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,335585,DB00008,10008531,45,1480,34,1642,0.109938598,1.468214155,0.914187159,2.377535799,0.225981314,DB0000810008531_,1.487302963,0.384046802,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,peginterferon alfa-2a,DB00008
,335599,DB08932,10003285,48,19395,8,6589,0.064172757,2.03842876,0.955191819,4.991153873,0.150962626,DB0893210003285_,1.890722981,0.712179295,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,335630,DB00126,10011781,64,10107,10,5935,9.84607788142456e-06,3.757942407,1.914780727,8.215722836,0.000107132,DB0012610011781_,9.141447063,1.323871575,female,10011781,Cystitis,10021881,Infections and infestations,Infec,ascorbic acid,DB00126
,335631,DB00736,10011781,47,10544,6,5547,0.000216162,4.120444854,1.756738687,11.80193853,0.001538124,DB0073610011781_,6.47719159,1.415961132,female,10011781,Cystitis,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,335651,DB00104,10022081,39,1442,14,1063,0.023671764,2.052997849,1.083829672,4.11567396,0.070473703,DB0010410022081_,2.652515644,0.71930109,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,octreotide,DB00104
,335653,DB00104,10022086,65,1416,34,1043,0.119866827,1.407986946,0.908395111,2.216877175,0.241192648,DB0010410022086_,1.422159296,0.342160987,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,octreotide,DB00104
,335654,DB00104,10025482,48,1433,22,1055,0.085010265,1.606007406,0.944123778,2.81211705,0.18680724,DB0010410025482_,1.677677994,0.473751227,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,octreotide,DB00104
,335684,DB05676,10010264,538,46591,239,25090,0.01391335,1.212187181,1.038171582,1.418772357,0.046336699,DB0567610010264_,3.071821006,0.192426316,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,335707,DB00798,10053762,36,771,36,608,0.332953274,0.78872172,0.476605998,1.305213936,0.501960242,DB0079810053762_,0.689234362,-0.23734172,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,gentamicin,DB00798
,335709,DB00490,10012735,186,3884,61,1515,0.276600826,1.189322609,0.880337375,1.625563741,0.440033452,DB0049010012735_,0.820904528,0.173383909,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,buspirone,DB00490
,335736,DB08932,10005725,52,19391,18,6579,0.891499379,0.98014547,0.563484819,1.781598071,0.954929174,DB0893210005725_,0.046118104,-0.02005428,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,macitentan,DB08932
,335832,DB04951,10012735,168,1714,155,2902,1.59400762431978e-07,1.834939066,1.453956656,2.316867572,2.77198084057197e-06,DB0495110012735_,12.79594839,0.607011275,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pirfenidone,DB04951
,335896,DB01020,10013709,58,1755,60,1818,1,1.001367167,0.681455362,1.470536645,1,DB0102010013709_,0,0.001366234,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,isosorbide mononitrate,DB01020
,335922,DB11133,10020937,50,2381,18,1556,0.032744162,1.815043823,1.036049805,3.318723385,0.09071648,DB1113310020937_,2.400016245,0.596109613,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,omega-3 fatty acids,DB11133
,336022,DB01060,10029331,78,8509,95,4986,2.34832465757921e-06,0.481128484,0.351215713,0.657475394,3.04536361422667e-05,DB0106010029331_,10.39930516,-0.731620925,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,amoxicillin,DB01060
,336064,DB00007,10037660,28,1919,64,4388,1,1.000374416,0.61557418,1.588481794,1,DB0000710037660_,0,0.000374346,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,leuprolide,DB00007
,336231,DB00635,10015946,42,33011,23,23771,0.316054322,1.314945936,0.772677246,2.291370241,0.483713998,DB0063510015946_,0.72626146,0.273795552,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,prednisone,DB00635
,336258,DB00635,10047115,38,33015,20,23774,0.28790005,1.368175716,0.776148859,2.482335874,0.452869708,DB0063510047115_,0.792150815,0.313478258,NA,10047115,Vasculitis,10047065,Vascular disorders,Vasc,prednisone,DB00635
,336264,DB08904,10047513,50,11560,6,3553,0.025695643,2.561247478,1.096326758,7.316613443,0.075024664,DB0890410047513_,2.589938364,0.940494436,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,certolizumab pegol,DB08904
,336278,DB00480,10017367,50,67378,36,67626,0.132158092,1.393991746,0.890132564,2.202928046,0.25889886,DB0048010017367_,1.351317796,0.332171391,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,336289,DB00421,10024670,38,8865,19,5233,0.585979882,1.180620002,0.663116908,2.170465448,0.733276897,DB0042110024670_,0.310231891,0.166039726,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,spironolactone,DB00421
,336450,DB00184,10010144,54,1240,12,970,2.16032560067691e-05,3.518427281,1.846128928,7.268138567,0.000213314,DB0018410010144_,8.452745799,1.258014095,female,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,nicotine,DB00184
,336453,DB00490,10010144,288,3782,96,1480,0.195219517,1.173938814,0.921009021,1.506746564,0.34330267,DB0049010010144_,1.069142801,0.160364602,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,buspirone,DB00490
,336454,DB00564,10010144,211,2393,99,1364,0.139374276,1.214752481,0.943038802,1.573156272,0.268975979,DB0056410010144_,1.313133199,0.194540336,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,carbamazepine,DB00564
,336478,DB00904,10018964,56,23013,54,14402,0.024129824,0.649028524,0.438267706,0.961860963,0.071545675,DB0090410018964_,2.637419216,-0.432278613,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ondansetron,DB00904
,336584,DB06643,10061224,81,52340,15,7500,0.354023395,0.773791564,0.442314344,1.446604834,0.523884866,DB0664310061224_,0.64648334,-0.256452739,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,denosumab,DB06643
,336586,DB00584,10010264,37,2044,27,1847,0.449741066,1.238226587,0.730581849,2.123578505,0.617356134,DB0058410010264_,0.482309219,0.213680184,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,enalapril,DB00584
,336595,DB00787,10011781,52,16948,24,17224,0.001174529,2.201891231,1.332509386,3.736562624,0.006290698,DB0078710011781_,5.068683323,0.789316641,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,acyclovir,DB00787
,336605,DB06643,10046306,84,52337,8,7507,0.343314562,1.506066176,0.729874171,3.603837132,0.512593026,DB0664310046306_,0.66827307,0.40950107,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,denosumab,DB06643
,336619,DB00331,10037867,46,24900,31,20721,0.422908013,1.234824279,0.766032921,2.015250041,0.591819045,DB0033110037867_,0.524554358,0.210928676,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,metformin,DB00331
,336646,DB00863,10005734,36,10637,18,5822,0.886768111,1.094673263,0.604935015,2.049625404,0.95296028,DB0086310005734_,0.048182056,0.090455929,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,ranitidine,DB00863
,336648,DB00394,10035664,60,1579,43,751,0.052753065,0.663757226,0.436652498,1.016228351,0.13020464,DB0039410035664_,2.038647913,-0.40983882,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,beclomethasone dipropionate,DB00394
,336682,DB00905,10053762,50,2668,16,909,0.887535137,1.064683687,0.592738673,2.013521993,0.953356575,DB0090510053762_,0.047766285,0.062677747,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,bimatoprost,DB00905
,336699,DB06643,10017076,173,52248,11,7504,0.00504438,2.258774107,1.230653528,4.611268826,0.020609549,DB0664310017076_,3.882000749,0.814822236,NA,10017076,Fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,336774,DB13867,10027599,45,4505,7,2547,0.000408637,3.634020732,1.623598189,9.563160549,0.002609261,DB1386710027599_,5.948688075,1.290339675,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,fluticasone,DB13867
,336840,DB00480,10057668,129,67299,121,67541,0.612867521,1.069981357,0.828193728,1.383059702,0.75468941,DB0048010057668_,0.281448992,0.067641225,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,336842,DB00497,10057668,36,19231,45,16330,0.093859018,0.679333993,0.425571977,1.077449448,0.201549813,DB0049710057668_,1.601718716,-0.386642383,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,oxycodone,DB00497
,336852,DB01015,10029444,29,9858,63,9318,0.000144508,0.435118504,0.269924423,0.686406727,0.001092746,DB0101510029444_,6.81906152,-0.832136862,NA,10029444,Nocardiosis,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,336859,DB00921,10015150,35,5810,20,4883,0.177100447,1.47072838,0.824627502,2.692453529,0.32016818,DB0092110015150_,1.138908859,0.385757775,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,buprenorphine,DB00921
,336881,DB00734,10034010,22,4028,37,4865,0.239143931,0.718175873,0.402860969,1.252218946,0.396870895,DB0073410034010_,0.924144252,-0.331040791,NA,10034010,Parkinsonism,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,336900,DB00437,10018836,19,6902,40,11506,0.423024135,0.791849497,0.432768057,1.400897509,0.591918519,DB0043710018836_,0.52438629,-0.233383935,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,336976,DB01175,10043882,35,10689,16,4876,1,0.997871775,0.537353337,1.93289511,1,DB0117510043882_,0,-0.002130493,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,escitalopram,DB01175
,337101,DB00904,10042604,31,23038,28,14428,0.180543265,0.693396652,0.402238681,1.200209857,0.324495178,DB0090410042604_,1.125484602,-0.366153074,NA,10042604,Supraventricular tachycardia,10007541,Cardiac disorders,Card,ondansetron,DB00904
,337126,DB00433,10076309,55,7601,25,5995,0.02348973,1.7350892,1.0617268,2.909470774,0.070019002,DB0043310076309_,2.658988621,0.551058824,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,prochlorperazine,DB00433
,337131,DB01216,10076309,8,228,46,7069,0.000290751,5.389219687,2.171304666,11.7016617,0.001966509,DB0121610076309_,6.231495348,1.684400604,female,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,finasteride,DB01216
,337139,DB00184,10037844,35,1259,15,967,0.061338101,1.791717912,0.947040012,3.552602927,0.145900364,DB0018410037844_,1.924831326,0.583174887,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,nicotine,DB00184
,337250,DB00950,10005750,59,4659,20,2036,0.389109031,1.289079331,0.762592066,2.266695766,0.559014587,DB0095010005750_,0.581579711,0.253928267,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,fexofenadine,DB00950
,337292,DB01222,10037884,35,9239,18,5387,0.775744011,1.133762361,0.62422944,2.128646056,0.877819546,DB0122210037884_,0.130314235,0.125541625,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,budesonide,DB01222
,337327,DB01076,10046543,52,25695,38,25545,0.170064037,1.36041958,0.877978416,2.12532556,0.310944157,DB0107610046543_,1.168141941,0.307793167,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,337334,DB00165,10016173,74,2071,30,1336,0.032363307,1.591044147,1.021593719,2.534226913,0.089889525,DB0016510016173_,2.409173867,0.464390497,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,pyridoxine,DB00165
,337337,DB05676,10014184,35,47094,18,25311,1,1.045056981,0.575940569,1.960446044,1,DB0567610014184_,0,0.044071411,NA,10014184,Eczema,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,337368,DB01276,10022095,32,1985,28,1483,0.59923849,0.853873597,0.495584961,1.478964966,0.743918373,DB0127610022095_,0.295823964,-0.157972109,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,exenatide,DB01276
,337382,DB01261,10040753,34,3747,18,3285,0.094017471,1.65587197,0.907300839,3.120683092,0.201784047,DB0126110040753_,1.600557227,0.50432774,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,sitagliptin,DB01261
,337579,DB06605,10043071,82,13991,52,12981,0.037146385,1.463060725,1.020331309,2.114606335,0.099878971,DB0660510043071_,2.303796113,0.380530628,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,apixaban,DB06605
,337617,DB01101,10062355,38,7551,13,3895,0.236551624,1.507748092,0.784525276,3.088446271,0.393815716,DB0110110062355_,0.931872204,0.410617208,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,337620,DB08877,10038695,27,3262,59,3170,0.000446805,0.444771399,0.270390483,0.714693387,0.002812661,DB0887710038695_,5.873624227,-0.81019484,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ruxolitinib,DB08877
,337660,DB00321,10047942,57,7390,19,2831,0.69974617,1.149236725,0.672104965,2.049696294,0.81955344,DB0032110047942_,0.198995673,0.139098005,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,amitriptyline,DB00321
,337722,DB01068,10051076,26,13737,36,6804,6.50805771209846e-05,0.357738972,0.207199147,0.609742364,0.000551376,DB0106810051076_,7.503094212,-1.027951688,male,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,337788,DB00213,10016970,47,18848,15,13406,0.00628966,2.228575771,1.223779767,4.292889118,0.024593473,DB0021310016970_,3.70527421,0.801362714,NA,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,337802,DB14500,10019974,42,7767,23,4050,0.895889625,0.952193396,0.558774607,1.661201667,0.956249434,DB1450010019974_,0.044736485,-0.048987118,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,potassium,DB14500
,337816,DB00404,10044034,42,19850,9,9853,0.017157922,2.316350269,1.110818446,5.4140692,0.054782384,DB0040410044034_,2.904386598,0.839992787,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,alprazolam,DB00404
,337838,DB00203,10013538,38,13840,13,8925,0.045303888,1.884952129,0.98152961,3.858648242,0.116171182,DB0020310013538_,2.152690469,0.633902425,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,sildenafil,DB00203
,337839,DB00374,10013538,45,17671,12,5712,0.644644852,1.212141136,0.630124227,2.519089878,0.780618245,DB0037410013538_,0.247669051,0.192388329,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,treprostinil,DB00374
,337944,DB01065,10050584,54,4277,18,3033,0.005311263,2.127213287,1.225215521,3.862409447,0.021466373,DB0106510050584_,3.841267606,0.754812807,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,melatonin,DB01065
,337956,DB00190,10012218,15,3282,37,4637,0.067745095,0.572819554,0.291544317,1.071312192,0.157262193,DB0019010012218_,1.849840848,-0.557184526,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,337962,DB00190,10033295,28,3269,42,4632,0.903140313,0.944629936,0.562620383,1.563985923,0.957326661,DB0019010033295_,0.043610607,-0.05696203,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,carbidopa,DB00190
,338093,DB00186,10064911,49,16852,11,9997,0.001946419,2.642445439,1.354791673,5.637592984,0.009523756,DB0018610064911_,4.653965931,0.971704791,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lorazepam,DB00186
,338138,DB00115,10045555,30,18395,24,10448,0.256540288,0.710009635,0.401049677,1.269747853,0.417365238,DB0011510045555_,0.873793571,-0.342476739,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,338149,DB00451,10061148,77,47194,25,15394,1,1.004651687,0.632344181,1.647484915,1,DB0045110061148_,0,0.004640901,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,338179,DB06403,10016100,41,21430,9,6652,0.407590949,1.414036454,0.676529613,3.310686443,0.577004341,DB0640310016100_,0.549905489,0.346448348,NA,10016100,Faeces discoloured,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,338252,DB00787,10052251,27,16973,32,17216,0.603173499,0.855834506,0.493042323,1.475253902,0.746917473,DB0078710052251_,0.291800578,-0.155678256,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,338284,DB05676,10001497,37,47092,27,25302,0.238759958,0.736314064,0.436246848,1.257701405,0.396475172,DB0567610001497_,0.925141858,-0.306098533,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,338303,DB05676,10062244,91,47038,34,25295,0.074409473,1.439283027,0.960544918,2.202488023,0.168855478,DB0567610062244_,1.778712091,0.364145091,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,338312,DB00635,10064687,44,33009,31,23763,1,1.021786903,0.63060801,1.674353001,1,DB0063510064687_,0,0.02155296,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,338326,DB00555,10022000,43,7004,14,3472,0.204055394,1.522502304,0.815681247,3.017513144,0.353900457,DB0055510022000_,1.038739601,0.420355234,NA,10022000,Influenza,10021881,Infections and infestations,Infec,lamotrigine,DB00555
,338338,DB01098,10023232,66,8083,38,7171,0.038040567,1.540827882,1.017132158,2.36411995,0.101703331,DB0109810023232_,2.285695219,0.432319858,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,338347,DB05676,10019303,109,47020,49,25280,0.317072991,1.195953568,0.845964632,1.712181547,0.484860293,DB0567610019303_,0.723894486,0.178943832,NA,10019303,Heart rate increased,10022891,Investigations,Inv,apremilast,DB05676
,338370,DB05676,10003553,91,47038,9,25320,2.68833210267022e-09,5.443250554,2.743652898,12.28489022,6.85381273702103e-08,DB0567610003553_,16.49587564,1.694376411,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,338383,DB11093,10028334,46,1611,7,653,0.012910322,2.662726136,1.18583313,7.027426748,0.043640636,DB1109310028334_,3.131766556,0.979350461,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium citrate,DB11093
,338401,DB01076,10051118,51,25696,32,25551,0.047439798,1.584733617,0.998708105,2.549070513,0.120275388,DB0107610051118_,2.117971266,0.460416328,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,338423,DB00181,10020100,47,9809,8,5863,0.000370703,3.51135352,1.642475164,8.610352288,0.00240591,DB0018110020100_,6.029827133,1.256001581,female,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,338442,DB00761,10067482,35,15272,15,8610,0.461290812,1.315468896,0.699582223,2.594097952,0.628630703,DB0076110067482_,0.464211312,0.274193177,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,338473,DB00289,10053762,34,449,31,532,0.307940494,1.2991831,0.761384801,2.224061895,0.475136023,DB0028910053762_,0.744154151,0.261735682,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,atomoxetine,DB00289
,338560,DB00722,10035742,30,25373,39,25993,0.337731438,0.788032571,0.472605029,1.302059631,0.506838187,DB0072210035742_,0.679563485,-0.238215857,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lisinopril,DB00722
,338707,DB00620,10010305,44,4784,16,3116,0.046651706,1.791054326,0.988779003,3.406581479,0.118798692,DB0062010010305_,2.130324886,0.582804456,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,triamcinolone,DB00620
,338781,DB00996,10061296,37,38916,21,22404,1,1.014331321,0.578228604,1.824294876,1,DB0099610061296_,0,0.014229598,NA,10061296,Motor dysfunction,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,338862,DB00318,10007515,19,4264,33,1806,7.65379233280325e-07,0.243924259,0.130677717,0.443098475,1.13101891157452e-05,DB0031810007515_,11.38980655,-1.410897516,male,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,codeine,DB00318
,338867,DB00924,10039906,102,10060,38,4213,0.577318579,1.124100891,0.76602321,1.680461176,0.726345915,DB0092410039906_,0.319728911,0.116983508,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,338895,DB00758,10019465,35,8265,22,10052,0.016002188,1.934789358,1.10267698,3.465042449,0.051835298,DB0075810019465_,2.959683941,0.659998462,NA,10019465,Hemiparesis,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,339005,DB00264,10069868,59,29548,21,24871,0.000440446,2.364717687,1.415314615,4.098846645,0.002778621,DB0026410069868_,5.885800403,0.860658644,NA,10069868,Device issue,10077536,Product issues,Prod,metoprolol,DB00264
,339035,DB00158,10051572,50,16765,9,8095,0.00335638,2.682417699,1.305167303,6.207532062,0.014804908,DB0015810051572_,4.21279654,0.986718514,NA,10051572,Injection site discolouration,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,339183,DB00451,10061520,118,47153,28,15391,0.148550987,1.375540324,0.904383823,2.158868063,0.281986184,DB0045110061520_,1.265897202,0.318846617,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,339219,DB00030,10033425,58,2148,29,1792,0.028920614,1.66832034,1.045658965,2.715293554,0.082297622,DB0003010033425_,2.497413061,0.511817336,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin human,DB00030
,339243,DB00588,10008629,33,16491,18,8450,0.882459352,0.939404513,0.513461614,1.773070405,0.950859822,DB0058810008629_,0.050388628,-0.062509101,NA,10008629,Cholelithiasis,10019805,Hepatobiliary disorders,Hepat,fluticasone propionate,DB00588
,339723,DB00502,10040047,21,1373,32,1840,0.677203637,0.879518298,0.479724258,1.580822007,0.804245873,DB0050210040047_,0.217850245,-0.12838091,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,haloperidol,DB00502
,339740,DB00843,10033371,45,2149,26,2147,0.030689344,1.728935232,1.039672225,2.930526438,0.086237911,DB0084310033371_,2.450645396,0.547505746,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,donepezil,DB00843
,339835,DB00843,10039906,31,2163,32,2141,0.899525459,0.958893541,0.563689991,1.629227786,0.956517739,DB0084310039906_,0.044455945,-0.04197522,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,donepezil,DB00843
,339932,DB01281,10016173,110,8822,17,1781,0.340723776,1.306261301,0.777360147,2.329213136,0.509960395,DB0128110016173_,0.673422213,0.267169088,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,abatacept,DB01281
,340010,DB13867,10017955,31,4519,25,2529,0.207755484,0.694015453,0.39555893,1.228898975,0.358594274,DB1386710017955_,1.025563685,-0.365261052,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,fluticasone,DB13867
,340012,DB01234,10037211,40,31585,32,32856,0.289538774,1.300291123,0.796265838,2.139079451,0.454705087,DB0123410037211_,0.78810623,0.26258818,NA,10037211,Psychomotor hyperactivity,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,340038,DB09053,10029366,26,2259,56,3996,0.487496524,0.821340228,0.493547328,1.33422307,0.651308637,DB0905310029366_,0.428771652,-0.196817849,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,ibrutinib,DB09053
,340044,DB00787,10015967,49,16951,30,17218,0.031889192,1.659025443,1.031774083,2.70851118,0.08886376,DB0078710015967_,2.420650873,0.506230348,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,acyclovir,DB00787
,340064,DB08904,10022437,52,11558,18,3541,0.671620083,0.885053622,0.508490856,1.609746951,0.800757065,DB0890410022437_,0.222197668,-0.122107046,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,certolizumab pegol,DB08904
,340070,DB00950,10017577,43,4675,14,2042,0.387455418,1.341467871,0.717990964,2.661238518,0.557529702,DB0095010017577_,0.584239499,0.29376444,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,fexofenadine,DB00950
,340106,DB00203,10029331,52,13826,58,8880,0.004354493,0.575861018,0.387902437,0.852938614,0.018295693,DB0020310029331_,4.00108961,-0.551888936,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,340135,DB00697,10020642,57,6039,17,1789,1,0.993279722,0.56784857,1.826291532,1,DB0069710020642_,0,-0.006742961,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,tizanidine,DB00697
,340159,DB08820,10022000,86,4315,89,3456,0.106144238,0.773960012,0.56667392,1.056658491,0.22041778,DB0882010022000_,1.512230535,-0.256235071,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ivacaftor,DB08820
,340224,DB00437,10029410,18,6903,42,11504,0.285133182,0.714236162,0.386665189,1.269142489,0.449728513,DB0043710029410_,0.799111182,-0.336541613,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,340234,DB00820,10001551,35,11880,30,5786,0.024509597,0.568213562,0.338548302,0.959154748,0.072418832,DB0082010001551_,2.625288898,-0.565257942,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,tadalafil,DB00820
,340257,DB06655,10028334,36,3652,25,2094,0.504315401,0.825711041,0.480621028,1.439319949,0.665390872,DB0665510028334_,0.407380634,-0.191510395,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,liraglutide,DB06655
,340322,DB00996,10061016,35,38918,32,22393,0.07461329,0.629366572,0.378281311,1.050295335,0.169193833,DB0099610061016_,1.776710281,-0.463041407,NA,10061016,Blood test abnormal,10022891,Investigations,Inv,gabapentin,DB00996
,340393,DB00921,10007617,64,5781,68,4835,0.187308882,0.78718445,0.549407256,1.126672932,0.33314707,DB0092110007617_,1.099171236,-0.239292687,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,buprenorphine,DB00921
,340421,DB00193,10054112,159,19161,80,8622,0.439989034,0.894337438,0.678527323,1.18661404,0.6083059,DB0019310054112_,0.497077399,-0.111672127,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,tramadol,DB00193
,340657,DB00697,10049848,79,6017,20,1786,0.629884508,1.172436399,0.708280702,2.028280987,0.768905704,DB0069710049848_,0.262786939,0.159083976,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,340702,DB00996,10018304,39,38914,12,22413,0.058603389,1.871858503,0.959968605,3.927976619,0.140887189,DB0099610018304_,1.959795785,0.626931789,NA,10018304,Glaucoma,10015919,Eye disorders,Eye,gabapentin,DB00996
,340715,DB00193,10048908,44,19276,7,8695,0.006042355,2.835256399,1.266267056,7.463871627,0.023796915,DB0019310048908_,3.738199309,1.042132374,female,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,tramadol,DB00193
,340936,DB01175,10022052,50,10674,7,4885,0.001398415,3.26861029,1.473576034,8.551889351,0.007252116,DB0117510022052_,4.926461973,1.184364907,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,340938,DB01175,10022081,38,10686,14,4878,0.551691263,1.238990216,0.655501971,2.477967685,0.7056204,DB0117510022081_,0.348677864,0.214296706,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,341007,DB01017,10040865,26,1443,33,868,0.00611631,0.474077221,0.270301746,0.823540401,0.024038161,DB0101710040865_,3.72811267,-0.746385058,NA,10040865,Skin hyperpigmentation,10040785,Skin and subcutaneous tissue disorders,Skin,minocycline,DB01017
,341011,DB00530,10001760,73,1735,8,1260,5.78970841014439e-10,6.623796936,3.1749734,15.97280797,1.67786643396522e-08,DB0053010001760_,17.90315774,1.890668761,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,erlotinib,DB00530
,341049,DB00787,10001949,56,16944,52,17196,0.700101266,1.092919918,0.735344126,1.626939799,0.819804953,DB0078710001949_,0.19868883,0.088852939,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,341114,DB00530,10040844,38,1770,15,1253,0.066449158,1.793046652,0.958622735,3.525179131,0.154972372,DB0053010040844_,1.864508423,0.583916213,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,erlotinib,DB00530
,341116,DB00787,10040844,76,16924,61,17187,0.198918373,1.265251195,0.890813106,1.803628553,0.347759857,DB0078710040844_,1.056243104,0.235270676,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,341118,DB00773,10042772,33,2290,17,2810,0.003859107,2.381584774,1.285135835,4.571048938,0.016563788,DB0077310042772_,4.10053641,0.867766138,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,etoposide,DB00773
,341130,DB00588,10057668,42,16482,16,8452,0.334605154,1.346109712,0.740564443,2.566352002,0.503742745,DB0058810057668_,0.685689567,0.297218738,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,341184,DB06605,10049438,42,14031,33,13000,0.490147413,1.179199006,0.729195582,1.921443834,0.653479563,DB0660510049438_,0.42544402,0.164835399,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,341201,DB09146,10053762,42,746,14,413,0.115749459,1.660217571,0.876287316,3.331992853,0.234804131,DB0914610053762_,1.449003598,0.506948661,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,iron sucrose,DB09146
,341216,DB00557,10022086,76,5911,28,3039,0.144972306,1.395436901,0.891777197,2.241159895,0.277013453,DB0055710022086_,1.283689206,0.333207557,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,341240,DB01076,10039674,35,25712,23,25560,0.147896799,1.512723223,0.868658971,2.682178678,0.281058985,DB0107610039674_,1.269190721,0.413911486,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,341288,DB00863,10001551,49,10624,34,5806,0.300953117,0.787629416,0.497653212,1.259620136,0.467261818,DB0086310001551_,0.760865539,-0.238727584,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,ranitidine,DB00863
,341298,DB00390,10033433,76,4069,16,3285,6.07100473107312e-08,3.834128782,2.210586854,7.057783663,1.15134458409998e-06,DB0039010033433_,13.6745801,1.343942234,female,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,digoxin,DB00390
,341398,DB00537,10016322,87,7470,31,4267,0.026454165,1.603036378,1.050765002,2.504169886,0.076766142,DB0053710016322_,2.566991593,0.471899567,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,341448,DB00028,10054996,50,13408,16,5599,0.417604784,1.304908779,0.730123842,2.45714835,0.586677805,DB0002810054996_,0.533279494,0.266133137,NA,10054996,Infusion site reaction,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,341449,DB00028,10059203,98,13360,26,5589,0.037945201,1.576801295,1.013291821,2.535392383,0.101506483,DB0002810059203_,2.287632606,0.455398298,NA,10059203,Infusion site bruising,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,341518,DB00734,10020772,25,4025,37,4865,0.446178359,0.816705121,0.470410934,1.396179891,0.614024842,DB0073410020772_,0.487719893,-0.202477178,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,risperidone,DB00734
,341536,DB01222,10001551,37,9237,34,5371,0.063634308,0.632820813,0.385870309,1.040602869,0.150024915,DB0122210001551_,1.896953898,-0.457567972,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,budesonide,DB01222
,341547,DB01222,10003481,37,9237,32,5373,0.104702167,0.672615908,0.407126717,1.116677432,0.218051793,DB0122210003481_,1.52302266,-0.396580828,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,budesonide,DB01222
,341669,DB00497,10011469,47,19220,7,16368,3.34732910632148e-07,5.717709814,2.567451588,15.00374931,5.39451536233354e-06,DB0049710011469_,12.13012779,1.743568343,female,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,341751,DB00928,10053762,17,818,40,1246,0.168895898,0.64749792,0.341748389,1.177675948,0.30939844,DB0092810053762_,1.173125384,-0.434639698,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,azacitidine,DB00928
,341811,DB08932,10024714,45,19398,38,6559,6.34939540592688e-05,0.400430068,0.253965564,0.63436872,0.000540284,DB0893210024714_,7.523414848,-0.915216139,NA,10024714,Liver transplant,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,341821,DB00177,10064848,48,4752,36,2814,0.3075773,0.789600253,0.500526367,1.25553822,0.474731024,DB0017710064848_,0.745006901,-0.23622847,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,valsartan,DB00177
,341824,DB00126,10062355,90,10081,39,5906,0.12016716,1.351947754,0.917394457,2.025238917,0.241584291,DB0012610062355_,1.420536837,0.301546334,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,ascorbic acid,DB00126
,341840,DB00571,10024264,45,5078,24,2585,0.898362416,0.954492032,0.567835045,1.641859064,0.956378206,DB0057110024264_,0.044601831,-0.046575984,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,propranolol,DB00571
,341851,DB00471,10037162,83,14106,22,5443,0.126643402,1.455676243,0.899846941,2.449607962,0.250976124,DB0047110037162_,1.382397467,0.375470564,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,341852,DB00472,10037162,50,10709,8,4304,0.012529273,2.511699809,1.180215593,6.140204113,0.042620931,DB0047210037162_,3.155409816,0.920959739,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,fluoxetine,DB00472
,341954,DB00641,10042609,46,14078,35,12440,0.577485705,1.161359171,0.731525771,1.858539856,0.726502713,DB0064110042609_,0.319513061,0.149591018,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,simvastatin,DB00641
,341978,DB09270,10027175,49,3065,26,2342,0.158734623,1.439960473,0.874574751,2.421653763,0.295805711,DB0927010027175_,1.218052421,0.364615664,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ubidecarenone,DB09270
,341995,DB08815,10010144,163,1291,46,657,0.000463232,1.802852841,1.273525889,2.593454382,0.002897677,DB0881510010144_,5.843845762,0.589370322,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,lurasidone,DB08815
,342069,DB08912,10047700,56,1274,30,1504,0.000587366,2.203079601,1.380122902,3.579456622,0.003532126,DB0891210047700_,5.645855192,0.7898562,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dabrafenib,DB08912
,342197,DB00571,10047513,48,5075,12,2597,0.027437905,2.046730982,1.068662584,4.240780645,0.078966968,DB0057110047513_,2.538725638,0.716243878,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,propranolol,DB00571
,342225,DB00761,10022687,37,15270,17,8608,0.570988734,1.226864319,0.673320656,2.325098741,0.72139819,DB0076110022687_,0.326564019,0.20446158,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,342280,DB01377,10007515,36,3760,25,2645,1,1.012977209,0.589883401,1.765103943,1,DB0137710007515_,0,0.012893727,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,magnesium oxide,DB01377
,342286,DB00537,10008469,37,7520,18,4280,0.673909637,1.169931072,0.648467723,2.185773147,0.802250258,DB0053710008469_,0.220334677,0.156944834,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,ciprofloxacin,DB00537
,342377,DB01012,10039906,35,10597,30,8655,0.900832498,0.952841331,0.567804757,1.608112658,0.956764412,DB0101210039906_,0.044198092,-0.048306883,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,cinacalcet,DB01012
,342397,DB00364,10061818,42,2708,24,1376,0.694105865,0.889247199,0.523706813,1.542004702,0.815819199,DB0036410061818_,0.203562519,-0.117380018,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,sucralfate,DB00364
,342469,DB00678,10060933,68,15531,36,10688,0.230296736,1.299867279,0.854880983,2.006301033,0.386265278,DB0067810060933_,0.951230898,0.262262166,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,342489,DB00281,10064774,52,11406,21,5650,0.457644392,1.226546164,0.725288549,2.146163413,0.624945745,DB0028110064774_,0.470090441,0.204202222,NA,10064774,Infusion site extravasation,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,342530,DB00557,10020642,51,5936,32,3035,0.414732521,0.814898099,0.512494837,1.31327034,0.58396305,DB0055710020642_,0.537917569,-0.204692206,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxyzine,DB00557
,342541,DB00115,10076309,129,18296,65,10407,0.454160147,1.128888836,0.830664265,1.546895893,0.621620468,DB0011510076309_,0.475425552,0.121233818,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,342542,DB00557,10076309,44,5943,18,3049,0.501173328,1.254024631,0.708541628,2.310166455,0.662635947,DB0055710076309_,0.41152954,0.226358084,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxyzine,DB00557
,342581,DB00364,10037844,83,2667,46,1354,0.637162985,0.91606482,0.627367009,1.351805433,0.774499498,DB0036410037844_,0.255538267,-0.087668153,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sucralfate,DB00364
,342583,DB00571,10037844,106,5017,35,2574,0.024467889,1.55374348,1.04781601,2.353983478,0.072327762,DB0057110037844_,2.62654724,0.440667168,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,propranolol,DB00571
,342594,DB00373,10069327,34,1798,25,1262,0.894184707,0.954614354,0.549958286,1.677953842,0.955860142,DB0037310069327_,0.045143671,-0.046447837,NA,10069327,Product quality issue,10077536,Product issues,Prod,timolol,DB00373
,342602,DB01109,10064373,34,4378,45,4225,0.17593615,0.729180559,0.45198295,1.166535447,0.318578238,DB0110910064373_,1.14388719,-0.315833897,NA,10064373,Labelled drug-drug interaction medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,heparin,DB01109
,342686,DB00169,10001480,73,38618,52,18123,0.026732961,0.65880597,0.455150764,0.959584965,0.077421317,DB0016910001480_,2.558493127,-0.417326218,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,342782,DB00203,10053664,48,13830,7,8931,2.21750954478918e-05,4.4279087,1.990890531,11.60438588,0.0002181,DB0020310053664_,8.430556655,1.487927396,female,10053664,Infusion site pruritus,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,342817,DB00818,10021143,42,1378,51,1626,0.916220646,0.971745746,0.625984406,1.501405787,0.962582824,DB0081810021143_,0.038135165,-0.028661087,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,propofol,DB00818
,342844,DB00115,10000060,144,18281,57,10415,0.022206201,1.439268129,1.051042797,1.993877442,0.067089405,DB0011510000060_,2.70172914,0.364134741,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,cyanocobalamin,DB00115
,342858,DB06589,10047895,54,1976,99,2554,0.04626778,0.705057792,0.493759599,0.997642896,0.118026845,DB0658910047895_,2.136843183,-0.349475505,NA,10047895,Weight decreased,10022891,Investigations,Inv,pazopanib,DB06589
,342883,DB00514,10013654,190,1976,297,1239,1.67081017449237e-20,0.401227843,0.328077227,0.489828055,1.81851947977358e-18,DB0051410013654_,40.84850898,-0.913225827,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,dextromethorphan,DB00514
,342887,DB08820,10016987,43,4358,35,3510,1,0.989510164,0.617106069,1.596465957,1,DB0882010016987_,0,-0.010545242,NA,10016987,Forced expiratory volume decreased,10022891,Investigations,Inv,ivacaftor,DB08820
,342891,DB06589,10003239,34,1996,39,2614,0.634349513,1.141684614,0.696330953,1.863563272,0.772654169,DB0658910003239_,0.257923719,0.132504903,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pazopanib,DB06589
,342898,DB06589,10019030,57,1973,104,2549,0.042840727,0.708135049,0.500633922,0.99312947,0.11139818,DB0658910019030_,2.19464429,-0.345120456,NA,10019030,Hair colour changes,10040785,Skin and subcutaneous tissue disorders,Skin,pazopanib,DB06589
,342937,DB00281,10042674,100,11358,23,5648,0.000488614,2.161962096,1.361581606,3.569780797,0.003035143,DB0028110042674_,5.797496673,0.771016187,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,342945,DB00281,10048634,85,11373,17,5654,0.000286805,2.485601361,1.463023517,4.468905798,0.001945211,DB0028110048634_,6.242384701,0.910514627,NA,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,342952,DB00588,10048634,42,16482,8,8460,0.006663273,2.694665812,1.249045967,6.647550773,0.025769755,DB0058810048634_,3.658553769,0.991274194,NA,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,342959,DB00281,10053483,76,11382,29,5642,0.25338478,1.299088477,0.835631225,2.069930428,0.413896713,DB0028110053483_,0.882138823,0.261662847,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,342961,DB00341,10053483,40,11365,13,5055,0.373140107,1.368601727,0.71629808,2.791491588,0.542852509,DB0034110053483_,0.610917619,0.313789581,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,342973,DB00281,10053505,76,11382,19,5652,0.006037805,1.986224077,1.18772414,3.481951735,0.023782964,DB0028110053505_,3.738785764,0.686235388,NA,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,342974,DB00316,10053505,116,65358,37,36916,0.001791627,1.770800426,1.213337297,2.638775852,0.008887133,DB0031610053505_,4.723150771,0.571431663,NA,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,342978,DB00451,10053505,47,47224,6,15413,0.024582754,2.55673587,1.090567617,7.319838065,0.072576472,DB0045110053505_,2.623114491,0.938731394,NA,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,342986,DB01075,10053505,118,19830,40,11057,0.005903259,1.64486404,1.139359425,2.41894253,0.02337031,DB0107510053505_,3.756288857,0.49765773,NA,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,343062,DB10631,10035664,76,1220,15,196,0.439711645,0.814107901,0.452530052,1.557223205,0.608034331,DB1063110035664_,0.497523933,-0.205662365,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,cranberry,DB10631
,343123,DB08931,10013950,46,6531,24,2422,0.178362558,0.710818553,0.423928351,1.220355466,0.32178683,DB0893110013950_,1.133865972,-0.341338082,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,343159,DB00193,10067482,46,19274,14,8688,0.211658357,1.48107612,0.799490558,2.918819414,0.363421623,DB0019310067482_,1.012191624,0.392768931,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,343369,DB00996,10029883,34,38919,19,22406,1,1.030216121,0.571065436,1.912381417,1,DB0099610029883_,0,0.029768607,NA,10029883,Obesity,10027433,Metabolism and nutrition disorders,Metab,gabapentin,DB00996
,343414,DB00028,10053484,56,13402,8,5607,0.002220431,2.928290046,1.387380708,7.118489807,0.010595268,DB0002810053484_,4.547347756,1.074418651,female,10053484,Infusion site warmth,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,343421,DB00316,10053664,66,65408,19,36934,0.008952895,1.96147502,1.162670177,3.461357697,0.032577953,DB0031610053664_,3.424119523,0.673696752,NA,10053664,Infusion site pruritus,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,343424,DB00668,10053664,66,10025,19,4284,0.153381746,1.484413295,0.878747904,2.622550031,0.288695968,DB0066810053664_,1.242381159,0.395019606,NA,10053664,Infusion site pruritus,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,343425,DB01075,10053664,71,19877,18,11079,0.001813476,2.198494855,1.295609599,3.921805051,0.008976876,DB0107510053664_,4.713103393,0.787772969,NA,10053664,Infusion site pruritus,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,343455,DB00413,10006451,40,2159,11,1196,0.038874915,2.014033592,1.009547483,4.369018757,0.103381944,DB0041310006451_,2.269324952,0.700139473,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,pramipexole,DB00413
,343561,DB00476,10051118,51,17206,20,6157,0.688201254,0.912487654,0.534034187,1.617233614,0.812014935,DB0047610051118_,0.208236546,-0.091580723,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,343582,DB00331,10038678,15,24931,39,20713,9.17086199667468e-05,0.319551036,0.163597911,0.593081781,0.000741255,DB0033110038678_,7.207165939,-1.140838281,male,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,metformin,DB00331
,343620,DB00316,10019194,63,65411,18,36935,0.010408383,1.976297382,1.155188226,3.547221103,0.036737524,DB0031610019194_,3.303956591,0.681225085,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,343655,DB00051,10049548,47,25684,21,11399,1,0.993305206,0.581870398,1.750141091,1,DB0005110049548_,0,-0.006717305,NA,10049548,Knee operation,10042613,Surgical and medical procedures,Surg,adalimumab,DB00051
,343806,DB00537,10007515,17,7540,37,4261,2.40426651326196e-06,0.259681087,0.136941356,0.473518561,3.10989119495433e-05,DB0053710007515_,10.37833772,-1.34830099,male,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,ciprofloxacin,DB00537
,344076,DB08910,10017918,36,16708,21,17467,0.033901257,1.792117744,1.017881973,3.232479084,0.093191231,DB0891010017918_,2.373101652,0.583398018,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,344114,DB01592,10005724,43,6233,14,3053,0.204575423,1.504362552,0.805783823,2.982119756,0.354595601,DB0159210005724_,1.036777291,0.408369255,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,iron,DB01592
,344136,DB01234,10013496,49,31576,31,32857,0.033070198,1.644745641,1.027755656,2.668985437,0.091447074,DB0123410013496_,2.391994904,0.497585747,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,344347,DB00404,10043882,75,19817,23,9839,0.041421384,1.618974447,1.002484924,2.708939303,0.108582933,DB0040410043882_,2.220241039,0.481792892,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,alprazolam,DB00404
,344365,DB00455,10035226,65,9336,34,5084,0.916101059,1.041067341,0.676341982,1.628439699,0.962495656,DB0045510035226_,0.038225726,0.040246476,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,loratadine,DB00455
,344418,DB00787,10028116,39,16961,49,17199,0.337895277,0.807093353,0.515749571,1.255362416,0.506976351,DB0078710028116_,0.679290922,-0.214315938,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,344429,DB08910,10053762,169,16575,153,17335,0.198322823,1.155216334,0.921738141,1.448765756,0.347064941,DB0891010053762_,1.058243367,0.144287629,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,pomalidomide,DB08910
,344488,DB05676,10062352,88,47041,37,25292,0.223229528,1.278787705,0.861419067,1.932356226,0.377506797,DB0567610062352_,0.974166705,0.245912524,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,apremilast,DB05676
,344537,DB14513,10016766,38,7139,19,3545,1,0.993135388,0.557589562,1.826625034,1,DB1451310016766_,0,-0.006888282,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,344541,DB00115,10028997,37,18388,27,10445,0.36223759,0.778439554,0.461015316,1.330172762,0.531907771,DB0011510028997_,0.631285168,-0.250463935,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyanocobalamin,DB00115
,344548,DB00104,10057362,51,1430,34,1043,0.738205465,1.094043372,0.689610655,1.754922786,0.849252917,DB0010410057362_,0.163398237,0.089880349,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,octreotide,DB00104
,344608,DB00316,10000125,31,65443,23,36930,0.323797476,0.760610203,0.429260901,1.366213849,0.492250819,DB0031610000125_,0.708766898,-0.27363427,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,344628,DB01065,10005750,45,4286,29,3022,0.723979778,1.094107764,0.669413424,1.81408354,0.837782406,DB0106510005750_,0.17699687,0.089939204,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,melatonin,DB01065
,344678,DB00230,10014011,42,19632,8,8643,0.030157539,2.311259031,1.071359856,5.703164013,0.085043548,DB0023010014011_,2.464591824,0.837792411,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,pregabalin,DB00230
,344693,DB00953,10016173,44,1653,7,225,0.662931964,0.855672115,0.376235768,2.279230328,0.794508786,DB0095310016173_,0.230031235,-0.155868019,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,rizatriptan,DB00953
,344698,DB14513,10016807,65,7112,32,3532,1,1.008769649,0.649613597,1.595384549,1,DB1451310016807_,0,0.008731419,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,magnesium,DB14513
,344794,DB14513,10060800,42,7135,13,3551,0.151636839,1.607848202,0.845352398,3.26924738,0.28622127,DB1451310060800_,1.250990095,0.474896765,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,magnesium,DB14513
,344844,DB00043,10028735,52,6361,21,2279,0.689104817,0.887185805,0.523816655,1.554210621,0.81249806,DB0004310028735_,0.207641753,-0.119700843,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omalizumab,DB00043
,344848,DB01050,10028735,71,18037,21,9350,0.026939359,1.752581475,1.063616105,3.005481319,0.07788177,DB0105010028735_,2.552563366,0.56108983,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,344852,DB00471,10028836,88,14101,12,5453,0.000191532,2.835523685,1.542861981,5.701111502,0.001388995,DB0047110028836_,6.579174524,1.042226642,female,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,344854,DB00043,10033425,132,6281,37,2263,0.187399583,1.285316312,0.883569725,1.910691395,0.33326329,DB0004310033425_,1.098822442,0.251004845,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,omalizumab,DB00043
,344909,DB00635,10041807,33,33020,23,23771,1,1.032898343,0.58830185,1.842772481,1,DB0063510041807_,0,0.032368776,NA,10041807,Sputum discoloured,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,345000,DB00343,10068319,70,8666,19,5076,0.001934241,2.157870675,1.282951352,3.799808773,0.009475635,DB0034310068319_,4.659031487,0.769121937,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,345067,DB01062,10022437,95,4391,32,1713,0.549211276,1.158125325,0.76517636,1.794408332,0.703578901,DB0106210022437_,0.351575254,0.146802598,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,oxybutynin,DB01062
,345354,DB00112,10005364,56,5877,31,4060,0.380918921,1.247921106,0.789258236,2.006336647,0.550937015,DB0011210005364_,0.596134786,0.221479052,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,bevacizumab,DB00112
,345395,DB01115,10010305,30,3570,25,2243,0.330659587,0.754001116,0.427404523,1.34082794,0.499375865,DB0111510010305_,0.694396231,-0.28236143,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,nifedipine,DB01115
,345404,DB00112,10020635,39,5894,31,4060,0.544876411,0.8666156,0.525950134,1.439092745,0.699764326,DB0011210020635_,0.357011677,-0.143159769,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,bevacizumab,DB00112
,345450,DB00112,10028596,40,5893,28,4063,1,0.984943325,0.591595228,1.660695479,1,DB0011210028596_,0,-0.015171178,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,bevacizumab,DB00112
,345474,DB01115,10047895,81,3519,40,2228,0.220570417,1.282035147,0.863886705,1.929598398,0.374177509,DB0111510047895_,0.98302497,0.248448774,NA,10047895,Weight decreased,10022891,Investigations,Inv,nifedipine,DB01115
,345588,DB01098,10035226,32,8117,45,7164,0.0511047,0.627646347,0.385569608,1.010935522,0.127102905,DB0109810035226_,2.062758248,-0.465778412,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,rosuvastatin,DB01098
,345589,DB00758,10061623,37,8263,43,10031,0.910476062,1.044595066,0.653798366,1.661689468,0.959615995,DB0075810061623_,0.04122208,0.043629314,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,345633,DB00996,10027951,63,38890,23,22402,0.072294315,1.577823325,0.964678234,2.666723933,0.165276708,DB0099610027951_,1.800134191,0.456046255,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,345639,DB00581,10047899,38,2075,24,2045,0.09661977,1.560269722,0.908294608,2.729649852,0.205706354,DB0058110047899_,1.581305591,0.444858705,NA,10047899,Weight increased,10022891,Investigations,Inv,lactulose,DB00581
,345658,DB00996,10072005,35,38918,15,22410,0.380277315,1.343587921,0.714834833,2.648633888,0.550357296,DB0099610072005_,0.597187582,0.295343588,NA,10072005,Spinal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,gabapentin,DB00996
,346043,DB00480,10024968,35,67393,46,67616,0.266326913,0.763391008,0.477314269,1.211255999,0.428473676,DB0048010024968_,0.847525977,-0.269984917,NA,10024968,Lower respiratory tract infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,346099,DB01225,10038980,12,5032,41,4599,2.09970146606573e-05,0.26750992,0.127807476,0.519639555,0.000208215,DB0122510038980_,8.476938532,-1.31859863,male,10038980,Retroperitoneal haemorrhage,10017947,Gastrointestinal disorders,Gastr,enoxaparin,DB01225
,346149,DB01098,10069326,29,8120,37,7172,0.140148261,0.692300144,0.410185797,1.158143995,0.270086132,DB0109810069326_,1.309014363,-0.367735683,NA,10069326,Product substitution issue,10077536,Product issues,Prod,rosuvastatin,DB01098
,346202,DB00198,10037660,58,1217,47,956,0.919941623,0.969388431,0.641962878,1.470246482,0.964555064,DB0019810037660_,0.036088358,-0.03108989,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,oseltamivir,DB00198
,346282,DB00654,10069293,39,3777,19,2579,0.282331387,1.401499887,0.78853824,2.573911701,0.446367357,DB0065410069293_,0.806612995,0.337543011,NA,10069293,Product container issue,10077536,Product issues,Prod,latanoprost,DB00654
,346413,DB01076,10021015,82,25665,71,25512,0.418589951,1.148040651,0.824889267,1.601157484,0.587616262,DB0107610021015_,0.53168116,0.138056707,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,346481,DB00563,10051398,38,46608,37,15311,5.20153396969031e-06,0.337391938,0.208739747,0.545761127,6.12555198894757e-05,DB0056310051398_,9.700456592,-1.086510002,male,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,methotrexate,DB00563
,346594,DB00999,10058920,42,21388,19,12220,0.427228181,1.263001592,0.718177724,2.300319432,0.595866112,DB0099910058920_,0.517739282,0.233491104,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,346700,DB00620,10000059,72,4756,37,3095,0.277702043,1.266292289,0.838083133,1.941999419,0.441317908,DB0062010000059_,0.817989783,0.236093173,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,triamcinolone,DB00620
,346760,DB01013,10028813,95,922,35,572,0.01057201,1.683407328,1.11399502,2.593492539,0.037205153,DB0101310028813_,3.291308002,0.520819911,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,clobetasol propionate,DB01013
,346774,DB01156,10065154,80,13542,29,6299,0.301856302,1.283104215,0.828572787,2.038118226,0.468224184,DB0115610065154_,0.758808072,0.24928231,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,bupropion,DB01156
,346794,DB00927,10006784,40,7457,10,5006,0.003483872,2.685047026,1.317977033,6.027439794,0.015268625,DB0092710006784_,4.181955216,0.987698242,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,famotidine,DB00927
,346801,DB08877,10029354,21,3268,38,3191,0.025636474,0.539664092,0.300185952,0.945568417,0.074914862,DB0887710029354_,2.591402983,-0.616808385,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,ruxolitinib,DB08877
,346884,DB09270,10006451,47,3067,17,2351,0.007334396,2.118984614,1.190768503,3.947059571,0.027786769,DB0927010006451_,3.583195321,0.750937018,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,ubidecarenone,DB09270
,346914,DB09033,10054236,32,2592,22,1647,0.780259093,0.924260359,0.518573063,1.675767682,0.880389357,DB0903310054236_,0.127391019,-0.078761473,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,vedolizumab,DB09033
,347335,DB08889,10003239,33,3132,18,3867,0.004624401,2.263324934,1.235169663,4.277980238,0.019208657,DB0888910003239_,3.952394205,0.816834942,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,carfilzomib,DB08889
,347378,DB00814,10042609,59,8228,32,3383,0.204832236,0.758075982,0.483942963,1.207267473,0.354865233,DB0081410042609_,1.036017188,-0.276971659,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,meloxicam,DB00814
,347467,DB00243,10010774,27,1227,37,1589,0.898802197,0.945028456,0.550128314,1.604571262,0.95647837,DB0024310010774_,0.044497104,-0.05654024,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ranolazine,DB00243
,347492,DB00572,10018884,37,2865,29,2097,0.802826772,0.933864469,0.556858044,1.579888717,0.893313651,DB0057210018884_,0.112817527,-0.06842396,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,atropine,DB00572
,347602,DB00295,10041101,33,14630,26,9576,0.506386632,0.830781542,0.481542431,1.447396282,0.66720332,DB0029510041101_,0.404660452,-0.185388405,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,morphine,DB00295
,347688,DB00874,10017577,34,3301,16,1960,0.556828413,1.261702778,0.675597977,2.454588479,0.710100421,DB0087410017577_,0.342348881,0.23246222,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,347691,DB00502,10070863,43,1351,94,1778,0.00618221,0.602118849,0.406689201,0.879281495,0.02423736,DB0050210070863_,3.71986004,-0.507300429,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,haloperidol,DB00502
,347701,DB00863,10003481,52,10621,30,5810,0.817600978,0.948187947,0.592976984,1.541302151,0.902513091,DB0086310003481_,0.102572084,-0.05320254,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,ranitidine,DB00863
,347727,DB00227,10070863,31,2436,32,1771,0.198450067,0.704362635,0.413975568,1.19695617,0.347236114,DB0022710070863_,1.057750285,-0.350461949,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,lovastatin,DB00227
,347785,DB09053,10022437,25,2260,32,4020,0.215931287,1.389533924,0.787331492,2.426884765,0.368508742,DB0905310022437_,0.998290846,0.328968385,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ibrutinib,DB09053
,347848,DB06273,10013573,101,4994,18,1392,0.091541343,1.563886909,0.937132055,2.754748482,0.197737124,DB0627310013573_,1.620816788,0.44717433,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,tocilizumab,DB06273
,347849,DB08904,10013573,148,11462,30,3529,0.040256475,1.518838097,1.018345411,2.334765659,0.106159163,DB0890410013573_,2.242815772,0.417945633,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,certolizumab pegol,DB08904
,347868,DB01076,10014011,49,25698,29,25554,0.030726349,1.680160373,1.040171939,2.759289386,0.086328051,DB0107610014011_,2.449600688,0.518889249,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,347869,DB01373,10014011,55,22665,10,7371,0.110937494,1.788575917,0.902420625,3.938001927,0.227509716,DB0137310014011_,1.480562333,0.581419726,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,calcium,DB01373
,347934,DB00476,10029354,62,17195,38,6139,0.011821256,0.582525694,0.382435564,0.897701216,0.040686357,DB0047610029354_,3.201862455,-0.540381985,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,duloxetine,DB00476
,347948,DB01060,10033557,53,8534,9,5072,0.000106832,3.499673439,1.70944158,8.077380029,0.000844616,DB0106010033557_,7.076628512,1.252669661,female,10033557,Palpitations,10007541,Cardiac disorders,Card,amoxicillin,DB01060
,347976,DB01012,10048959,30,10602,22,8663,0.780681308,1.11420386,0.621070935,2.028807913,0.88062004,DB0101210048959_,0.127129028,0.108140123,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,347992,DB00572,10047899,29,2873,32,2094,0.117874378,0.660593045,0.384237108,1.131304146,0.238012524,DB0057210047899_,1.435431984,-0.414617294,NA,10047899,Weight increased,10022891,Investigations,Inv,atropine,DB00572
,348010,DB09027,10022437,246,4933,302,6850,0.169914095,1.131103576,0.9480832,1.348463506,0.310799721,DB0902710022437_,1.168606557,0.123193772,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ledipasvir,DB09027
,348026,DB00165,10028334,55,2090,24,1342,0.129489082,1.471336402,0.890652853,2.498076356,0.254914658,DB0016510028334_,1.366826465,0.386171105,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,pyridoxine,DB00165
,348047,DB00051,10007554,34,25697,23,11397,0.11635519,0.655638654,0.374891045,1.166267585,0.235669133,DB0005110007554_,1.445326435,-0.422145474,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,adalimumab,DB00051
,348058,DB06724,10023547,50,7879,22,3897,0.707423756,1.124087528,0.667175873,1.952230559,0.825089674,DB0672410023547_,0.192263203,0.11697162,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,calcium carbonate,DB06724
,348064,DB01060,10017944,44,8543,20,5061,0.365574863,1.303288251,0.75115777,2.337081858,0.535178795,DB0106010017944_,0.625154391,0.264890494,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,348065,DB00254,10061822,49,5886,20,3368,0.212001265,1.401854422,0.816428755,2.494118189,0.363784648,DB0025410061822_,1.011193212,0.337795948,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,348070,DB09073,10015090,388,19872,12,778,0.506681298,1.265861617,0.712232199,2.482179577,0.667374119,DB0907310015090_,0.404404492,0.23575301,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,palbociclib,DB09073
,348072,DB00646,10010264,62,3391,25,1975,0.14451943,1.444319207,0.891104577,2.407047278,0.276348991,DB0064610010264_,1.286090753,0.367638074,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,nystatin,DB00646
,348145,DB00186,10013774,63,16838,8,10000,1.55997767450159e-06,4.676573544,2.232804452,11.30532634,2.13284853962415e-05,DB0018610013774_,10.75546704,1.542565693,female,10013774,Dry eye,10015919,Eye disorders,Eye,lorazepam,DB00186
,348164,DB13867,10020937,48,4502,21,2533,0.378828007,1.286005593,0.753368512,2.266633822,0.548800061,DB1386710020937_,0.600021092,0.251540975,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,fluticasone,DB13867
,348180,DB00874,10041349,29,3306,31,1945,0.022391517,0.55045756,0.31901625,0.947283561,0.067497106,DB0087410041349_,2.695670557,-0.597005419,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,guaifenesin,DB00874
,348190,DB00482,10061623,52,8207,14,3057,0.331670999,1.383450648,0.754180873,2.707419767,0.500515111,DB0048210061623_,0.692117489,0.324580848,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,348202,DB00761,10043882,42,15265,14,8611,0.094801043,1.69226765,0.905339709,3.356922722,0.20293005,DB0076110043882_,1.59489394,0.526069434,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,potassium chloride,DB00761
,348214,DB06637,10003239,59,6103,23,1996,0.519507491,0.838951216,0.508750232,1.427457787,0.678707444,DB0663710003239_,0.387565108,-0.17560272,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,dalfampridine,DB06637
,348215,DB06637,10010264,169,5993,63,1956,0.395353955,0.875560856,0.648706767,1.194232588,0.565042842,DB0663710010264_,0.570853723,-0.132890619,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,348218,DB06605,10052904,46,14027,24,13009,0.02261534,1.777521569,1.062081269,3.046748613,0.067990936,DB0660510052904_,2.688380881,0.575220017,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,348239,DB00073,10047924,47,7359,33,6374,0.370657194,1.233588198,0.772706583,1.990090849,0.540357802,DB0007310047924_,0.615523763,0.209927156,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rituximab,DB00073
,348495,DB00804,10017577,56,2944,7,892,0.022901589,2.423593755,1.096694205,6.326082928,0.068666888,DB0080410017577_,2.678488176,0.885251461,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,dicyclomine,DB00804
,348498,DB00184,10019211,32,1262,19,963,0.475040001,1.285038202,0.701623655,2.415276558,0.640641668,DB0018410019211_,0.445284999,0.250788447,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,nicotine,DB00184
,348536,DB00028,10033775,79,13379,29,5586,0.597806,1.137370275,0.733714335,1.808115207,0.742861971,DB0002810033775_,0.297245024,0.128718821,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,human immunoglobulin g,DB00028
,348648,DB01175,10013754,35,10689,20,4872,0.466539058,0.797680145,0.447390619,1.459834198,0.633271148,DB0117510013754_,0.456856594,-0.226047583,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,348711,DB08889,10007554,24,3141,40,3845,0.257062086,0.734512046,0.422539393,1.251622791,0.417929608,DB0888910007554_,0.872442263,-0.308548883,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,carfilzomib,DB08889
,348731,DB00887,10017577,35,2306,20,1795,0.338151979,1.362106826,0.761858865,2.499143469,0.507252092,DB0088710017577_,0.678747177,0.309032638,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,348800,DB00264,10022094,41,29566,9,24883,5.12931839610461e-05,3.833818803,1.835023291,8.973246307,0.000451748,DB0026410022094_,7.702386475,1.343861383,female,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,349065,DB00999,10076308,116,21314,36,12203,0.000938521,1.844801231,1.258573808,2.763275254,0.005226488,DB0099910076308_,5.254015783,0.612371538,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,349075,DB00584,10017955,24,2057,41,1833,0.011969124,0.521711459,0.300283651,0.888069939,0.041068915,DB0058410017955_,3.192503779,-0.650640604,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,enalapril,DB00584
,349119,DB00688,10066901,50,6440,33,5345,0.321452465,1.257503519,0.79299155,2.018102966,0.489768386,DB0068810066901_,0.713822682,0.229128422,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,349375,DB01109,10047899,30,4382,23,4247,0.412009681,1.264127154,0.708699684,2.282843639,0.581427814,DB0110910047899_,0.542268453,0.234381887,NA,10047899,Weight increased,10022891,Investigations,Inv,heparin,DB01109
,349558,DB00334,10001540,33,2816,19,2793,0.069420427,1.722484078,0.948572984,3.214538703,0.160269699,DB0033410001540_,1.830897261,0.54376748,NA,10001540,Akathisia,10029205,Nervous system disorders,Nerv,olanzapine,DB00334
,349687,DB00996,10044034,93,38860,61,22364,0.451025614,0.877410347,0.628219907,1.233089071,0.618683241,DB0099610044034_,0.480161863,-0.130780497,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,349706,DB00028,10062352,95,13363,26,5589,0.057209284,1.528203107,0.980337338,2.460621548,0.138192899,DB0002810062352_,1.979104751,0.424092605,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,349717,DB00668,10062352,83,10008,28,4275,0.299743309,1.266173431,0.814808802,2.022137868,0.465771209,DB0066810062352_,0.764060734,0.235999306,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,epinephrine,DB00668
,349722,DB01075,10062352,104,19844,34,11063,0.005732015,1.705261756,1.146923582,2.593222499,0.022824725,DB0107510062352_,3.7799109,0.533718621,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,349726,DB09153,10062352,51,7748,26,5673,0.164558734,1.436178071,0.877659446,2.402934902,0.303485447,DB0915310062352_,1.19242162,0.361985468,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,sodium chloride,DB09153
,349775,DB00051,10022611,87,25644,13,11407,4.82409651437936e-05,2.976719774,1.65216055,5.817137384,0.0004286,DB0005110022611_,7.754985947,1.090821947,female,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,adalimumab,DB00051
,349788,DB00381,10039163,57,29303,13,22874,1.03422796344917e-05,3.422505027,1.850399355,6.818111491,0.000111733,DB0038110039163_,9.099396875,1.230372747,female,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,amlodipine,DB00381
,349793,DB00158,10043417,41,16774,12,8092,0.142710591,1.648215152,0.849310621,3.447025399,0.27362666,DB0015810043417_,1.295990655,0.499692976,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,349838,DB06605,10047899,169,13904,108,12925,0.002465464,1.454608941,1.134428413,1.87185982,0.0115393,DB0660510047899_,4.461996651,0.374737095,NA,10047899,Weight increased,10022891,Investigations,Inv,apixaban,DB06605
,349955,DB00571,10076309,77,5046,43,2566,0.627493169,0.910622153,0.617065148,1.359367886,0.766909446,DB0057110076309_,0.265386548,-0.093627229,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,propranolol,DB00571
,349956,DB00741,10076309,36,4058,26,3148,0.798812928,1.0741255,0.629284302,1.856836233,0.891356522,DB0074110076309_,0.115010795,0.071506842,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocortisone,DB00741
,349964,DB00758,10001949,41,8259,34,10040,0.10429239,1.465875998,0.906727497,2.383856871,0.217470442,DB0075810001949_,1.525692335,0.382453015,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,clopidogrel,DB00758
,350057,DB00425,10001488,30,12665,36,7448,0.00462677,0.490072509,0.291295125,0.819136629,0.019213187,DB0042510001488_,3.952158435,-0.713201921,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,zolpidem,DB00425
,350264,DB00381,10007697,35,29325,16,22871,0.08953074,1.706038124,0.91943693,3.302054835,0.194496921,DB0038110007697_,1.637338946,0.534173796,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,350265,DB01076,10007697,37,25710,14,25569,0.001764864,2.62847048,1.387440001,5.26382381,0.008770102,DB0107610007697_,4.736406837,0.966402111,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,350270,DB01076,10014387,70,25677,40,25543,0.005423867,1.740838337,1.16356962,2.636535808,0.021825833,DB0107610014387_,3.824661022,0.5543668,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,atorvastatin,DB01076
,350345,DB06228,10013839,21,15891,32,16044,0.168921668,0.662580238,0.362947898,1.185579071,0.30939844,DB0622810013839_,1.173125384,-0.411613614,NA,10013839,Duodenal ulcer haemorrhage,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,350423,DB01611,10028836,81,11832,9,2352,0.115908627,1.78897689,0.895579846,4.058460782,0.235036316,DB0161110028836_,1.44801524,0.581643886,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,350442,DB05332,10016256,81,948,40,747,0.022331868,1.595248763,1.065093233,2.421969003,0.067373676,DB0533210016256_,2.697500904,0.467029688,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,romiplostim,DB05332
,350558,DB00480,10005483,168,67260,194,67468,0.188429835,0.868658962,0.702103191,1.073856812,0.334540913,DB0048010005483_,1.094996096,-0.14080468,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,lenalidomide,DB00480
,350842,DB00915,10028245,40,1415,15,1036,0.027028702,1.951918382,1.048287076,3.825204914,0.078079945,DB0091510028245_,2.550022037,0.668812675,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,amantadine,DB00915
,350854,DB06228,10039163,47,15865,21,16055,0.001463215,2.264852186,1.326776153,3.990692457,0.007535388,DB0622810039163_,4.888144992,0.817509497,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,350945,DB01067,10039906,20,4341,30,4793,0.321751413,0.736108298,0.395561919,1.342047537,0.490061474,DB0106710039906_,0.713224439,-0.306378027,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,glipizide,DB01067
,350949,DB00678,10049414,34,15565,30,10694,0.372709332,0.778677762,0.462153332,1.318102588,0.542420951,DB0067810049414_,0.611712916,-0.250157975,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,350968,DB00682,10064373,56,19403,82,16282,0.001450616,0.573093455,0.400291175,0.815377936,0.007481495,DB0068210064373_,4.895322634,-0.556706477,NA,10064373,Labelled drug-drug interaction medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,350994,DB00829,10008469,58,7994,11,4443,0.000368282,2.930326801,1.520792168,6.198506369,0.002394041,DB0082910008469_,6.034772592,1.075113953,female,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,351020,DB00678,10018627,31,15568,45,10679,0.001438107,0.472556803,0.288897556,0.763966918,0.007427182,DB0067810018627_,4.902608725,-0.749597321,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,losartan,DB00678
,351040,DB00540,10021097,52,2431,11,1080,0.026317128,2.099776163,1.077034158,4.48082694,0.076461338,DB0054010021097_,2.570970055,0.74183075,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,nortriptyline,DB00540
,351059,DB00316,10061481,50,65424,41,36912,0.080710124,0.688075469,0.446051322,1.066695732,0.179534177,DB0031610061481_,1.717389689,-0.373856754,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,351214,DB00695,10019194,45,28004,18,20510,0.029801233,1.830957948,1.038619111,3.361850341,0.08426478,DB0069510019194_,2.47379129,0.604839299,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,351249,DB00531,10013710,44,7208,50,6466,0.2563983,0.789428295,0.51346357,1.209871411,0.417224621,DB0053110013710_,0.874130543,-0.236446273,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,351385,DB06674,10065154,97,4409,41,1449,0.194873475,0.777562879,0.531639421,1.155053708,0.342852211,DB0667410065154_,1.070455796,-0.251590764,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,golimumab,DB06674
,351390,DB00480,10018870,64,67364,79,67583,0.241455911,0.81276299,0.575107808,1.144834585,0.399575683,DB0048010018870_,0.917352089,-0.207315737,NA,10018870,Blood urine present,10022891,Investigations,Inv,lenalidomide,DB00480
,351407,DB00065,10057362,69,9395,35,4922,0.917809998,1.03282185,0.677036101,1.601147077,0.96352088,DB0006510057362_,0.037161121,0.032294717,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,infliximab,DB00065
,351437,DB00264,10051076,45,29562,30,24862,0.354516468,1.261511528,0.777196311,2.074651735,0.524363591,DB0026410051076_,0.645569959,0.232310628,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,351555,DB00734,10020737,27,4023,30,4872,0.7901884,1.089921854,0.622307141,1.900491205,0.886342292,DB0073410020737_,0.120652069,0.086106001,NA,10020737,Hyperprolactinaemia,10014698,Endocrine disorders,Endo,risperidone,DB00734
,351567,DB00341,10022000,110,11295,70,4998,0.022657604,0.695362133,0.509669288,0.954098442,0.068098464,DB0034110022000_,2.68680062,-0.363322515,NA,10022000,Influenza,10021881,Infections and infestations,Infec,cetirizine,DB00341
,351713,DB00820,10040753,216,11699,47,5769,6.31292871423076e-08,2.266159608,1.643630298,3.18194307,1.19420893309504e-06,DB0082010040753_,13.63802657,0.818086596,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,tadalafil,DB00820
,351722,DB00126,10062244,33,10138,17,5928,0.769661747,1.135078471,0.613725043,2.174723032,0.873852947,DB0012610062244_,0.134843171,0.126701786,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,351813,DB00624,10035664,6,556,89,4307,0.14072572,0.522283792,0.185792558,1.190263421,0.270848323,DB0062410035664_,1.306196307,-0.649544176,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,testosterone,DB00624
,351829,DB00455,10074902,31,9370,23,5095,0.25704368,0.73293156,0.413208982,1.317768337,0.417912607,DB0045510074902_,0.872482942,-0.310702951,NA,10074902,Expired product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,351995,DB00126,10021143,33,10138,41,5904,0.001504223,0.468746926,0.286826894,0.760793462,0.007711069,DB0012610021143_,4.865098447,-0.757692259,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ascorbic acid,DB00126
,352098,DB00472,10060933,43,10716,16,4296,0.885788988,1.077401614,0.593871828,2.051423311,0.952502191,DB0047210060933_,0.048662872,0.074552229,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,fluoxetine,DB00472
,352123,DB00211,10008190,22,1414,30,1601,0.575971635,0.830366564,0.454126547,1.496230036,0.725363027,DB0021110008190_,0.321083022,-0.185888033,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,midodrine,DB00211
,352125,DB00211,10012174,30,1406,37,1594,0.804844314,0.919281709,0.545317283,1.538130013,0.894427482,DB0021110012174_,0.11157145,-0.084162665,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,midodrine,DB00211
,352153,DB00804,10000087,81,2919,23,876,0.906236919,1.056843869,0.653599875,1.7714303,0.958144782,DB0080410000087_,0.042756383,0.055286985,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,dicyclomine,DB00804
,352162,DB00374,10042604,37,17679,17,5707,0.265628653,0.702603406,0.385503985,1.331713135,0.427716806,DB0037410042604_,0.849293972,-0.352962692,NA,10042604,Supraventricular tachycardia,10007541,Cardiac disorders,Card,treprostinil,DB00374
,352180,DB01006,10008479,63,5884,9,168,0.000203723,0.199952182,0.096787285,0.465192657,0.001463397,DB0100610008479_,6.526994526,-1.609677032,male,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,letrozole,DB01006
,352185,DB01175,10013971,43,10681,13,4879,0.247594309,1.510892095,0.796584049,3.0654932,0.406865456,DB0117510013971_,0.899272722,0.412700268,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,escitalopram,DB01175
,352187,DB11089,10013971,58,10117,36,8371,0.17881807,1.333042099,0.863725123,2.082585973,0.322408545,DB1108910013971_,1.131935764,0.287463623,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,docusate,DB11089
,352238,DB00047,10010144,21,9264,36,8482,0.023543841,0.534115775,0.296012421,0.940783931,0.070156429,DB0004710010144_,2.657027834,-0.627142657,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,insulin glargine,DB00047
,352277,DB08889,10033661,30,3135,44,3841,0.48236598,0.835384754,0.505806776,1.362696538,0.646804733,DB0888910033661_,0.435710834,-0.179862877,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,carfilzomib,DB08889
,352368,DB00318,10003549,39,4244,19,1820,0.666722065,0.880279348,0.495008687,1.617362437,0.79739686,DB0031810003549_,0.226402782,-0.127515981,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,codeine,DB00318
,352369,DB00410,10003549,55,1550,37,972,0.744760795,0.932196754,0.598411009,1.466571683,0.854246317,DB0041010003549_,0.157535699,-0.070211378,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,mupirocin,DB00410
,352393,DB00318,10025482,65,4218,21,1818,0.287080084,1.333970847,0.802037695,2.30502251,0.451890889,DB0031810025482_,0.794314523,0.288160093,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,codeine,DB00318
,352394,DB00410,10025482,67,1538,21,988,0.003632451,2.049023182,1.229824653,3.546481867,0.015788172,DB0041010025482_,4.148494204,0.717363183,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,mupirocin,DB00410
,352452,DB00410,10046571,51,1554,14,995,0.004225248,2.3317863,1.263125054,4.586651562,0.017856843,DB0041010046571_,4.025368479,0.846634626,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,mupirocin,DB00410
,352463,DB01076,10047302,23,25724,56,25527,0.000173724,0.407554784,0.239274897,0.67341859,0.001280769,DB0107610047302_,6.660294241,-0.897579915,NA,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,352467,DB00410,10047700,68,1537,22,987,0.005584356,1.984379011,1.202202445,3.394358431,0.022350179,DB0041010047700_,3.800920927,0.685306024,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,mupirocin,DB00410
,352568,DB08828,10047700,38,724,40,1102,0.124865439,1.445670992,0.893023927,2.336884013,0.248379602,DB0882810047700_,1.39279705,0.368573568,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,vismodegib,DB08828
,352606,DB00641,10012671,32,14092,31,12444,0.800696916,0.911543415,0.538283142,1.545480015,0.892281272,DB0064110012671_,0.113973868,-0.092616056,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,simvastatin,DB00641
,352608,DB00904,10012671,38,23031,22,14434,0.792598091,1.082526537,0.623848321,1.922374597,0.887586947,DB0090410012671_,0.119248793,0.079297695,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,ondansetron,DB00904
,352611,DB00165,10010774,61,2084,27,1339,0.121288526,1.451458943,0.90328864,2.388381465,0.243286581,DB0016510010774_,1.413515184,0.372569218,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,pyridoxine,DB00165
,352657,DB00480,10013774,206,67222,109,67553,3.52981617899208e-08,1.899193682,1.498212332,2.418719819,7.02618644256e-07,DB0048010013774_,14.16845156,0.641429418,NA,10013774,Dry eye,10015919,Eye disorders,Eye,lenalidomide,DB00480
,352733,DB01590,10002855,38,4700,24,2843,0.895658144,0.957776594,0.558475648,1.672846738,0.95615204,DB0159010002855_,0.044838341,-0.043140728,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,everolimus,DB01590
,352745,DB01590,10076309,33,4705,26,2841,0.345542014,0.766436578,0.443528454,1.33738802,0.514943409,DB0159010076309_,0.66369827,-0.266003326,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,everolimus,DB01590
,352854,DB00374,10001551,32,17684,20,5704,0.023235831,0.51606911,0.285998171,0.952953452,0.069427511,DB0037410001551_,2.667472073,-0.661514589,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,treprostinil,DB00374
,352856,DB00374,10003481,45,17671,19,5705,0.311124635,0.764643175,0.43786795,1.385540158,0.478619846,DB0037410003481_,0.736848637,-0.268345992,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,treprostinil,DB00374
,352882,DB01015,10051398,26,9861,52,9329,0.001981991,0.473045946,0.283280826,0.772209294,0.009654674,DB0101510051398_,4.64031314,-0.748562758,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sulfamethoxazole,DB01015
,352900,DB08820,10008479,36,4365,32,3513,0.714183685,0.905424425,0.545408073,1.509173093,0.830523301,DB0882010008479_,0.185699294,-0.099351467,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ivacaftor,DB08820
,352904,DB06605,10028810,198,13875,83,12950,2.74565341168951e-10,2.226330141,1.712561155,2.916187036,8.38205574056431e-09,DB0660510028810_,18.59717264,0.800354553,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,apixaban,DB06605
,352942,DB00722,10017918,49,25354,26,26006,0.007445483,1.933043125,1.177724783,3.241327165,0.028130589,DB0072210017918_,3.570897709,0.65909551,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,lisinopril,DB00722
,353039,DB00331,10016766,90,24856,73,20679,0.937224092,1.025696739,0.744455447,1.417237697,0.977247169,DB0033110016766_,0.023015672,0.025372127,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,353049,DB00175,10020100,32,8099,23,6083,0.892503052,1.044984765,0.591988665,1.87209623,0.955189036,DB0017510020100_,0.045846015,0.044002306,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,353091,DB00285,10046543,39,10912,15,3703,0.641418849,0.88233499,0.474893943,1.725031395,0.778145729,DB0028510046543_,0.25084146,-0.125183487,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,venlafaxine,DB00285
,353092,DB06637,10046543,60,6102,18,2001,0.793496159,1.09307197,0.634811558,1.972190723,0.888018693,DB0663710046543_,0.118762485,0.088992054,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,dalfampridine,DB06637
,353098,DB06637,10050256,50,6112,14,2005,0.664757992,1.171557839,0.636007648,2.300011232,0.795939233,DB0663710050256_,0.228232437,0.15833435,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,dalfampridine,DB06637
,353126,DB00904,10013754,57,23012,26,14430,0.213979434,1.374706078,0.84994988,2.278855796,0.366210856,DB0090410013754_,1.004546002,0.318239947,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,353129,DB01142,10019211,85,1655,15,769,0.000240063,2.632206328,1.497301702,4.941752654,0.001677984,DB0114210019211_,6.390162457,0.967822403,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,doxepin,DB01142
,353131,DB00364,10027175,46,2704,9,1391,0.005872269,2.628766347,1.26659671,6.126766156,0.023277423,DB0036410027175_,3.760271378,0.966514667,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,sucralfate,DB00364
,353137,DB00904,10027951,40,23029,16,14440,0.132812126,1.567569922,0.858097244,2.999628826,0.259718297,DB0090410027951_,1.348157709,0.4495266,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,353187,DB01015,10043607,64,9823,99,9282,0.002096556,0.610881002,0.438363541,0.846150772,0.010113412,DB0101510043607_,4.593892808,-0.492853098,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,sulfamethoxazole,DB01015
,353208,DB06262,10012174,30,3770,49,4265,0.140333745,0.692665142,0.423567732,1.115785021,0.270321534,DB0626210012174_,1.308143163,-0.367208597,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,droxidopa,DB06262
,353238,DB00115,10013496,43,18382,16,10456,0.174950074,1.528675114,0.843227223,2.908867201,0.317393982,DB0011510013496_,1.147611432,0.424401422,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,353324,DB00264,10063829,37,29570,30,24862,0.903021035,1.036973144,0.623159791,1.73856947,0.957326661,DB0026410063829_,0.043610607,0.036306031,NA,10063829,Device malfunction,10077536,Product issues,Prod,metoprolol,DB00264
,353371,DB00243,10012735,37,1217,36,1590,0.23247402,1.342629578,0.819928226,2.200525389,0.388906415,DB0024310012735_,0.944416543,0.294630063,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ranolazine,DB00243
,353449,DB00213,10011781,88,18807,17,13404,4.04615163667252e-08,3.689184431,2.177091183,6.619907354,7.9635414279249e-07,DB0021310011781_,14.04322185,1.305405412,female,10011781,Cystitis,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,353452,DB01062,10011781,42,4444,10,1735,0.213565719,1.639664912,0.807285416,3.673180352,0.365717119,DB0106210011781_,1.005895143,0.494491899,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,oxybutynin,DB01062
,353453,DB01098,10011781,37,8112,13,7196,0.002752805,2.524513824,1.310357924,5.179934286,0.012601442,DB0109810011781_,4.373944038,0.926048499,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,rosuvastatin,DB01098
,353542,DB00321,10038435,50,7397,27,2823,0.159398428,0.706768629,0.433132175,1.176561452,0.296668429,DB0032110038435_,1.215140164,-0.347051924,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,amitriptyline,DB00321
,353563,DB00327,10042458,40,6098,11,4251,0.004143411,2.534739539,1.274621906,5.484119292,0.017578815,DB0032710042458_,4.041060772,0.930090886,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,hydromorphone,DB00327
,353616,DB00722,10022067,49,25354,28,26004,0.016056728,1.794832336,1.105609501,2.966771555,0.051963938,DB0072210022067_,2.957205306,0.584911611,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,353660,DB00153,10076308,32,7391,22,3417,0.185875663,0.672481977,0.378145044,1.216718068,0.331304116,DB0015310076308_,1.104718546,-0.396779967,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ergocalciferol,DB00153
,353662,DB00471,10076308,69,14120,34,5431,0.269720332,0.780572011,0.509871648,1.2157026,0.432279438,DB0047110076308_,0.838683053,-0.247728281,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,353663,DB00758,10076308,31,8269,41,10033,0.812642861,0.917372096,0.555705499,1.500519245,0.899249273,DB0075810076308_,0.106195005,-0.086242114,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,353683,DB01240,10038776,39,5712,16,1560,0.186539905,0.665745472,0.362411741,1.2796633,0.332138961,DB0124010038776_,1.10220184,-0.406847856,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,epoprostenol,DB01240
,353684,DB06403,10038776,49,21422,9,6652,0.164977866,1.690540568,0.82122451,3.916757725,0.304109064,DB0640310038776_,1.190368878,0.525048341,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,353706,DB00878,10069339,18,1168,33,887,0.002526264,0.414398712,0.218173426,0.763417794,0.011752927,DB0087810069339_,4.443652974,-0.880926696,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,chlorhexidine,DB00878
,353709,DB01050,10017918,42,18066,8,9363,0.006611292,2.720812294,1.26123476,6.712558582,0.025593196,DB0105010017918_,3.665428739,1.000930473,female,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,ibuprofen,DB01050
,353711,DB01268,10010305,25,2118,35,3095,0.895276821,1.043798112,0.596931174,1.80044626,0.956133237,DB0126810010305_,0.044858006,0.042866091,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,sunitinib,DB01268
,353720,DB00188,10005750,33,7853,32,8796,0.619114415,1.155072579,0.687738002,1.94216498,0.75999337,DB0018810005750_,0.27444557,0.144163181,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,bortezomib,DB00188
,353760,DB00572,10007515,17,2885,39,2087,5.33845477976852e-05,0.31539791,0.166819416,0.572599825,0.000466882,DB0057210007515_,7.66943473,-1.15392023,male,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,atropine,DB00572
,353826,DB01015,10038428,18,9869,34,9347,0.017830556,0.501430711,0.266433673,0.913826063,0.056453404,DB0101510038428_,2.874339696,-0.690289845,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,sulfamethoxazole,DB01015
,353921,DB01075,10019196,36,19912,17,11080,0.667681031,1.178332268,0.644642996,2.238238693,0.798169392,DB0107510019196_,0.225434433,0.164100107,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,353954,DB00433,10028596,24,7632,38,5982,0.006870646,0.495054611,0.283768285,0.848000936,0.026414354,DB0043310028596_,3.633847718,-0.703087198,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,prochlorperazine,DB00433
,354035,DB00193,10039674,50,19270,17,8685,0.356333461,1.325528316,0.751047358,2.453140632,0.526015109,DB0019310039674_,0.642425342,0.281811109,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,tramadol,DB00193
,354036,DB00338,10039674,51,33623,22,22250,0.095085469,1.534042955,0.913493357,2.657189044,0.203345663,DB0033810039674_,1.592847974,0.427906705,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,354109,DB00996,10021639,46,38907,17,22408,0.14913905,1.558407976,0.876303481,2.900322728,0.282796128,DB0099610021639_,1.263029038,0.443664772,NA,10021639,Incontinence,10038359,Renal and urinary disorders,Renal,gabapentin,DB00996
,354171,DB00480,10005802,69,67359,46,67616,0.031931102,1.505710438,1.021879554,2.23711651,0.088967796,DB0048010005802_,2.419480819,0.409264839,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,354247,DB00213,10016326,35,18860,15,13406,0.114119613,1.658543426,0.882215665,3.270080901,0.23230844,DB0021310016326_,1.459689309,0.505939763,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,354260,DB00950,10044565,41,4677,12,2044,0.293156172,1.493134828,0.767884042,3.127666307,0.458790151,DB0095010044565_,0.77916236,0.400877821,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,fexofenadine,DB00950
,354262,DB13867,10044565,46,4504,18,2536,0.238576694,1.438848722,0.816227208,2.642617719,0.396296031,DB1386710044565_,0.925593794,0.363843295,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,fluticasone,DB13867
,354264,DB00213,10048010,62,18833,14,13407,2.14133061670054e-05,3.152513712,1.744325788,6.101658135,0.000211756,DB0021310048010_,8.460073572,1.148200138,female,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,354267,DB00678,10048010,43,15556,13,10711,0.009053824,2.277415245,1.201367682,4.618392596,0.032883758,DB0067810048010_,3.414776428,0.823041135,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,354471,DB01409,10007554,36,5995,33,3933,0.175339045,0.7157273,0.43296971,1.186686405,0.317869287,DB0140910007554_,1.146115029,-0.33445605,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,tiotropium,DB01409
,354513,DB01076,10029412,32,25715,54,25529,0.017421174,0.588316013,0.367470225,0.928017721,0.055454502,DB0107610029412_,2.892192386,-0.530491038,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,354615,DB08877,10069339,22,3267,51,3178,0.000553674,0.419659972,0.241764876,0.706461794,0.003359106,DB0887710069339_,5.696080302,-0.868310486,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ruxolitinib,DB08877
,354616,DB00254,10022086,51,5884,7,3381,4.95790179379738e-05,4.185956172,1.888609092,10.94351744,0.000438561,DB0025410022086_,7.732011281,1.431735154,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,354669,DB06262,10016256,299,3501,230,4084,4.10881583035112e-06,1.516384506,1.264885278,1.819725869,4.97009774969072e-05,DB0626210016256_,9.909485957,0.416328887,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,354670,DB06262,10022437,76,3724,62,4252,0.05808159,1.399536181,0.984489863,1.996087991,0.13983738,DB0626210022437_,1.967275103,0.336140882,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,droxidopa,DB06262
,354671,DB06262,10050256,24,3776,34,4280,0.430551539,0.800122453,0.453093912,1.392355953,0.599039128,DB0626210050256_,0.51242836,-0.222990497,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,354683,DB00193,10047461,62,19258,15,8687,0.026602266,1.864449304,1.047468191,3.531126441,0.077093778,DB0019310047461_,2.562732707,0.62296573,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,tramadol,DB00193
,354698,DB00190,10047513,32,3265,23,4651,0.013061593,1.981774732,1.121639738,3.553583128,0.044052604,DB0019010047513_,3.122370814,0.683992773,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,carbidopa,DB00190
,354701,DB06262,10047513,44,3756,41,4273,0.383109116,1.220855204,0.777601624,1.920476444,0.553186891,DB0626210047513_,0.592059376,0.1995516,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,droxidopa,DB06262
,354716,DB08932,10003662,75,19368,28,6569,0.650807618,0.90847811,0.580883373,1.45823176,0.785277802,DB0893210003662_,0.241717736,-0.095984486,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,macitentan,DB08932
,354725,DB00904,10020578,20,23049,41,14415,7.9312890838433e-06,0.305086167,0.16926941,0.533060122,8.87878763069937e-05,DB0090410020578_,9.329260445,-1.187161029,male,10020578,Hyperbilirubinaemia,10019805,Hepatobiliary disorders,Hepat,ondansetron,DB00904
,354790,DB01234,10086210,34,31591,25,32863,0.194878579,1.414744974,0.819375428,2.474109596,0.342852211,DB0123410086210_,1.070455796,0.346949285,NA,10086210,Superficial vein thrombosis,10047065,Vascular disorders,Vasc,dexamethasone,DB01234
,354811,DB01098,10055798,25,8124,45,7164,0.003831106,0.489933386,0.287622467,0.817163446,0.01647454,DB0109810055798_,4.105939115,-0.713485843,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,rosuvastatin,DB01098
,354830,DB00254,10069339,89,5846,89,3299,0.000199221,0.564383176,0.414526992,0.768303168,0.001435056,DB0025410069339_,6.546551573,-0.572021868,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,doxycycline,DB00254
,354831,DB01156,10069339,108,13514,78,6250,0.003322732,0.640371212,0.473353348,0.869629412,0.014692238,DB0115610069339_,4.220435925,-0.445707252,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,bupropion,DB01156
,354834,DB08904,10017533,65,11545,9,3550,0.019186388,2.220570945,1.09916739,5.07808767,0.059834396,DB0890410017533_,2.816174597,0.797764345,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,354841,DB05676,10017626,56,47073,27,25302,0.729973596,1.114818548,0.692284352,1.836288225,0.84284454,DB0567610017626_,0.170972751,0.108691655,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,apremilast,DB05676
,354844,DB00972,10011224,76,2428,26,1153,0.162850073,1.387994322,0.873333683,2.270941218,0.301168942,DB0097210011224_,1.200083902,0.327859771,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azelastine,DB00972
,354926,DB00480,10049946,25,67403,33,67629,0.358081726,0.760119716,0.433283219,1.317938792,0.527795557,DB0048010049946_,0.639046272,-0.274279338,NA,10049946,Cervical vertebral fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,354957,DB08931,10010305,67,6510,22,2424,0.719267662,1.1339576,0.689733811,1.932703184,0.834257811,DB0893110010305_,0.181212799,0.125713815,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,riociguat,DB08931
,355064,DB06643,10076309,35,52386,17,7498,0.000128501,0.294700949,0.160620357,0.561227794,0.000987614,DB0664310076309_,6.920218322,-1.221794169,male,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,355146,DB00567,10018884,35,4484,26,2055,0.071370638,0.616981715,0.359850578,1.070405644,0.163647859,DB0056710018884_,1.81003836,-0.482915891,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,cephalexin,DB00567
,355195,DB00073,10011831,23,7383,37,6370,0.019317654,0.536360817,0.303931131,0.927959148,0.060161674,DB0007310011831_,2.810719773,-0.622948178,NA,10011831,Cytomegalovirus infection,10021881,Infections and infestations,Infec,rituximab,DB00073
,355221,DB09027,10033295,25,5154,47,7105,0.232080837,0.733284976,0.431881383,1.217642658,0.388434873,DB0902710033295_,0.94562976,-0.310220872,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,ledipasvir,DB09027
,355239,DB00814,10030124,50,8237,17,3398,0.590058417,1.213287886,0.68673393,2.247413657,0.736732163,DB0081410030124_,0.305530868,0.193333936,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,355368,DB00905,10028813,39,2679,17,908,0.438601596,0.777607814,0.42724418,1.473558346,0.606921239,DB0090510028813_,0.499356252,-0.251532977,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,bimatoprost,DB00905
,355380,DB00334,10046571,39,2810,17,2795,0.004413627,2.281689482,1.257276362,4.312002911,0.018487999,DB0033410046571_,3.990633445,0.824916169,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,olanzapine,DB00334
,355441,DB08932,10016326,74,19369,19,6578,0.338958918,1.322680803,0.789806327,2.321378583,0.508057234,DB0893210016326_,0.677161171,0.279660588,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,355587,DB00207,10001760,65,9015,7,5448,1.29160016636774e-07,5.610311035,2.571940773,14.52212329,2.2938993495254e-06,DB0020710001760_,12.98525742,1.724606161,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,azithromycin,DB00207
,355634,DB00557,10049848,41,5946,16,3051,0.401353292,1.314858128,0.720627834,2.514122106,0.571173323,DB0055710049848_,0.560062572,0.273728772,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,hydroxyzine,DB00557
,355719,DB00115,10024774,30,18395,41,10431,0.000275253,0.414929339,0.24999401,0.681400427,0.00188118,DB0011510024774_,6.275855934,-0.879647042,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,355721,DB00213,10024774,42,18853,23,13398,0.377990177,1.297708939,0.762365268,2.261892106,0.547952338,DB0021310024774_,0.60156697,0.260600355,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,355724,DB00588,10024774,39,16485,25,8443,0.427580589,0.79899935,0.471112992,1.378473307,0.596136201,DB0058810024774_,0.517286113,-0.224395146,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,355819,DB00005,10067768,101,127981,18,42401,0.014218308,1.858900535,1.11855486,3.263353029,0.047161113,DB0000510067768_,3.054185611,0.619985203,NA,10067768,Antibiotic therapy,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,355860,DB06605,10001760,149,13924,20,13013,1.21865459100207e-23,6.962132487,4.346961972,11.73164381,1.71295914034702e-21,DB0660510001760_,47.81606459,1.940485819,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,apixaban,DB06605
,355883,DB00852,10013709,50,1116,20,451,1,1.010301309,0.582897845,1.813046729,1,DB0085210013709_,0,0.010248612,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pseudoephedrine,DB00852
,355894,DB01118,10047895,53,3010,79,4630,0.85789585,1.031976299,0.712256528,1.484892197,0.932059951,DB0111810047895_,0.070358141,0.031475701,NA,10047895,Weight decreased,10022891,Investigations,Inv,amiodarone,DB01118
,356053,DB00773,10021036,23,2300,46,2781,0.051480079,0.604623512,0.348682814,1.021736061,0.127788636,DB0077310021036_,2.057377658,-0.503149309,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,etoposide,DB00773
,356059,DB00370,10037844,78,4463,60,3603,0.796269993,1.049499697,0.737697188,1.499389857,0.889699623,DB0037010037844_,0.116871375,0.048313571,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,mirtazapine,DB00370
,356075,DB08868,10012374,74,9128,32,2479,0.032109478,0.628061985,0.408541231,0.985309185,0.08934028,DB0886810012374_,2.415302831,-0.465116415,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,fingolimod,DB08868
,356153,DB01202,10012218,21,6693,33,5685,0.028426489,0.540557205,0.29685168,0.963783033,0.081220747,DB0120210012218_,2.510584563,-0.61515481,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,356203,DB06605,10005483,48,14025,93,12940,2.05563017801789e-05,0.476216558,0.328625282,0.682368191,0.000204513,DB0660510005483_,8.49488078,-0.741882574,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,apixaban,DB06605
,356257,DB06262,10047700,106,3694,42,4272,1.01509445113457e-09,2.918343563,2.017356456,4.289726476,2.81750344752611e-08,DB0626210047700_,17.38482955,1.071016182,female,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,droxidopa,DB06262
,356313,DB09270,10022000,37,3077,32,2336,0.625630035,0.87782571,0.530268523,1.460345275,0.76522501,DB0927010022000_,0.267585358,-0.130307213,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ubidecarenone,DB09270
,356348,DB00586,10062355,44,7065,16,2789,0.885983219,1.08558822,0.599384718,2.064694971,0.952535694,DB0058610062355_,0.048627699,0.082121979,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,356351,DB00887,10062355,31,2310,20,1795,0.571560648,1.204383476,0.662426672,2.237580832,0.721692445,DB0088710062355_,0.326156207,0.185967798,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,bumetanide,DB00887
,356393,DB00193,10013082,48,19272,13,8689,0.126594554,1.664691546,0.887169366,3.35099694,0.250917931,DB0019310013082_,1.382629363,0.509639849,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,356437,DB00318,10013654,115,4168,547,1292,7.78149070672646e-197,0.065212995,0.05232875,0.080691929,5.11341208065763e-193,DB0031810013654_,442.767056,-2.730096515,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,codeine,DB00318
,356460,DB00874,10025482,112,3223,39,1937,0.003546116,1.725762651,1.183119331,2.564140084,0.015479475,DB0087410025482_,4.168240334,0.545669069,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,guaifenesin,DB00874
,356484,DB05676,10017918,107,47022,24,25305,3.20793947332655e-05,2.399235231,1.529429137,3.908220264,0.000300984,DB0567610017918_,8.108453196,0.875150033,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,apremilast,DB05676
,356488,DB00285,10038669,124,10827,51,3667,0.255739672,0.823470925,0.588444844,1.167129358,0.416462256,DB0028510038669_,0.875959444,-0.194227036,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,venlafaxine,DB00285
,356490,DB01069,10013654,152,6548,69,2326,0.104191618,0.782534051,0.582547224,1.060098702,0.217337928,DB0106910013654_,1.526301863,-0.245217842,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,promethazine,DB01069
,356501,DB11750,10027175,34,2466,20,1493,1,1.029231856,0.573296318,1.894437405,1,DB1175010027175_,0,0.028812753,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,clobetasol,DB11750
,356506,DB00091,10012378,64,5446,14,2656,0.004966309,2.229288353,1.234086026,4.313267986,0.020353853,DB0009110012378_,3.894485061,0.80168241,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,cyclosporine,DB00091
,356508,DB01075,10074903,127,19821,113,10984,0.000321663,0.622798927,0.479038042,0.810679939,0.002135891,DB0107510074903_,6.148871559,-0.473531561,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,356528,DB08931,10043521,48,6529,12,2434,0.245338226,1.491072809,0.778639293,3.089434023,0.404137051,DB0893110043521_,0.906001224,0.399495867,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,356530,DB00887,10033433,45,2296,18,1797,0.014972028,1.956347364,1.105645237,3.604107846,0.049243081,DB0088710033433_,3.010986412,0.671079145,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,bumetanide,DB00887
,356531,DB01115,10033433,46,3554,12,2256,0.004220537,2.432985433,1.264936128,5.056576193,0.017839801,DB0111510033433_,4.026323282,0.889119077,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,nifedipine,DB01115
,356532,DB05676,10024774,36,47093,22,25307,0.67983511,0.879361153,0.503371786,1.569420678,0.806365644,DB0567610024774_,0.215217987,-0.128559598,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,apremilast,DB05676
,356535,DB05676,10000496,42,47087,26,25303,0.611190923,0.868062118,0.519826527,1.475099162,0.753242376,DB0567610000496_,0.283368222,-0.141492002,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,356537,DB05676,10043269,144,46985,69,25260,0.471947357,1.121977062,0.836049533,1.518103723,0.638049507,DB0567610043269_,0.449339402,0.115092363,NA,10043269,Tension headache,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,356550,DB00193,10038669,107,19213,35,8667,0.10224936,1.379109758,0.932744773,2.083924575,0.21434956,DB0019310038669_,1.54014714,0.321438188,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tramadol,DB00193
,356562,DB00313,10010144,210,1029,213,1304,0.038249458,1.249290994,1.009682653,1.545738398,0.102124353,DB0031310010144_,2.281564063,0.222576186,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,valproic acid,DB00313
,356565,DB00656,10074903,91,11922,47,6572,0.788970886,1.067315222,0.741580371,1.553846316,0.88567613,DB0065610074903_,0.121403937,0.065146357,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,356592,DB05676,10029412,44,47085,24,25305,1,0.985286654,0.586021235,1.694417662,1,DB0567610029412_,0,-0.014822661,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,356641,DB01175,10013496,46,10678,23,4869,0.698326684,0.911977265,0.540860429,1.578225357,0.818583936,DB0117510013496_,0.200179339,-0.092140218,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,356652,DB05676,10008479,146,46983,82,25247,0.780894904,0.95678318,0.724752284,1.270343499,0.880700697,DB0567610008479_,0.127037442,-0.044178475,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,356674,DB00333,10074903,65,3006,80,3072,0.275926209,0.830365217,0.586814481,1.17133193,0.439265968,DB0033310074903_,0.822650201,-0.185889655,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,methadone,DB00333
,356689,DB00921,10007515,38,5807,39,4864,0.421845918,0.816151047,0.507232402,1.312170314,0.590908918,DB0092110007515_,0.526093389,-0.203155834,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,buprenorphine,DB00921
,356723,DB09079,10047895,40,617,51,826,0.827905266,1.049923475,0.666955104,1.643218147,0.909547717,DB0907910047895_,0.094807818,0.048717281,NA,10047895,Weight decreased,10022891,Investigations,Inv,nintedanib,DB09079
,356730,DB00264,10022067,34,29573,24,24868,0.598263709,1.19127359,0.68576331,2.100370593,0.743094301,DB0026410022067_,0.296932323,0.175022978,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,356731,DB00381,10022067,45,29315,20,22867,0.034020901,1.755071212,1.014995851,3.138718739,0.093446823,DB0038110022067_,2.370362739,0.562509432,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,356787,DB00472,10013654,252,10507,139,4173,0.002617426,0.720054725,0.581178565,0.895078421,0.01209441,DB0047210013654_,4.415011947,-0.328428063,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,fluoxetine,DB00472
,356796,DB06228,10075192,136,15776,174,15902,0.039853657,0.787859483,0.624147611,0.992828809,0.105398267,DB0622810075192_,2.25000909,-0.238435527,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,rivaroxaban,DB06228
,356799,DB00318,10010144,111,4172,84,1755,9.19503432198344e-05,0.555959076,0.412531361,0.751459137,0.000742752,DB0031810010144_,7.205148449,-0.587060591,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,codeine,DB00318
,356800,DB00924,10010144,609,9553,248,4003,0.728290065,1.029015063,0.882073998,1.203112507,0.841510621,DB0092410010144_,0.172556644,0.028602096,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,cyclobenzaprine,DB00924
,356802,DB00697,10010144,218,5878,82,1724,0.068062778,0.779767105,0.598584569,1.023779675,0.157797585,DB0069710010144_,1.846442176,-0.248759987,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,tizanidine,DB00697
,356803,DB00734,10010144,274,3776,166,4736,2.24509140220672e-13,2.070100078,1.692511835,2.537872633,1.10097439378738e-11,DB0073410010144_,25.23224042,0.727596953,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,risperidone,DB00734
,356847,DB00514,10010144,151,2015,91,1445,0.2245111,1.189893414,0.902939106,1.574974459,0.3791618,DB0051410010144_,0.969792252,0.173863735,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,dextromethorphan,DB00514
,356880,DB01114,10013654,29,591,79,344,6.67122145276789e-13,0.213995561,0.131950719,0.339020301,3.05759469722762e-11,DB0111410013654_,24.21080746,-1.541800008,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,chlorpheniramine,DB01114
,356881,DB00370,10010144,371,4170,222,3441,0.00026187,1.378960428,1.157203148,1.646081636,0.001804967,DB0037010010144_,6.317212959,0.321329902,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,mirtazapine,DB00370
,356883,DB01098,10010144,73,8076,14,7195,1.80904052358644e-09,4.64497888,2.596631156,8.92104974,4.76405683694327e-08,DB0109810010144_,16.85958116,1.535786825,female,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,rosuvastatin,DB01098
,356892,DB01592,10061822,31,6245,23,3044,0.145561876,0.656988171,0.370152738,1.182129094,0.277816868,DB0159210061822_,1.280793131,-0.420089266,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,iron,DB01592
,356893,DB05676,10061822,124,47005,68,25261,0.879871047,0.97997371,0.723014167,1.337947479,0.949545405,DB0567610061822_,0.05177193,-0.020229534,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,356913,DB00381,10010144,1576,27784,1359,21528,0.005176283,0.898559934,0.833283987,0.969004517,0.02102915,DB0038110010144_,3.861845688,-0.106961871,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,356914,DB00641,10010144,93,14031,212,12263,1.42467086317428e-15,0.383414953,0.296807072,0.4921499,9.40891297450651e-14,DB0064110010144_,29.99453387,-0.958637449,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,simvastatin,DB00641
,356915,DB01136,10010144,210,9674,377,10738,2.18632907327138e-08,0.618310748,0.518600325,0.735643837,4.54829122999115e-07,DB0113610010144_,14.60334404,-0.48076412,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,carvedilol,DB01136
,356917,DB06700,10010144,92,2133,24,594,0.908469274,1.06747272,0.667961892,1.766423167,0.959026229,DB0670010010144_,0.041836854,0.065293911,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,desvenlafaxine,DB06700
,356918,DB00737,10070863,58,2743,27,905,0.162412136,0.708810853,0.438642581,1.17170316,0.300570513,DB0073710070863_,1.2020729,-0.344166567,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,meclizine,DB00737
,356937,DB00586,10010144,69,7040,62,2743,3.34667954096939e-06,0.433658403,0.302336797,0.623169496,4.16512650257484e-05,DB0058610010144_,10.08617882,-0.835498144,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,diclofenac,DB00586
,356939,DB00343,10010144,653,8083,326,4769,0.017697887,1.181767699,1.028036114,1.360541214,0.056138172,DB0034310010144_,2.879939266,0.167011368,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,diltiazem,DB00343
,356940,DB00557,10010144,422,5565,305,2762,2.48659458610792e-06,0.686713785,0.587019028,0.80405163,3.20392836744346e-05,DB0055710010144_,10.34854779,-0.375837689,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,hydroxyzine,DB00557
,356943,DB05676,10005750,176,46953,61,25268,0.002629638,1.552700887,1.153766892,2.114183015,0.012143366,DB0567610005750_,4.410972244,0.439995922,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,apremilast,DB05676
,356946,DB00252,10010144,71,2161,97,1811,0.002581508,0.613490389,0.442261427,0.84758992,0.011963141,DB0025210010144_,4.425924912,-0.488590681,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,phenytoin,DB00252
,356950,DB00331,10010144,684,24262,826,19926,1.96996840147786e-13,0.680109038,0.612587208,0.754863661,9.71493797989599e-12,DB0033110010144_,25.35735642,-0.385502144,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,metformin,DB00331
,356953,DB00472,10038669,89,10670,16,4296,0.001606453,2.239498635,1.304140645,4.091743684,0.008123435,DB0047210038669_,4.813002203,0.806252017,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluoxetine,DB00472
,356954,DB00211,10005750,55,1381,59,1572,0.774784775,1.061079056,0.715873365,1.570715073,0.877243929,DB0021110005750_,0.130970185,0.059286368,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,midodrine,DB00211
,356956,DB00687,10010305,29,957,44,1041,0.189909789,0.71705808,0.428916339,1.182728564,0.336384569,DB0068710010305_,1.089500224,-0.332598437,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,fludrocortisone,DB00687
,356957,DB06262,10010305,92,3708,140,4174,0.027566402,0.739757642,0.560189282,0.973058269,0.079263019,DB0626210010305_,2.534983601,-0.301432658,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,droxidopa,DB06262
,356970,DB06262,10036653,88,3712,69,4245,0.023458524,1.458408449,1.048614812,2.035381128,0.069945963,DB0626210036653_,2.660032291,0.377345737,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,356991,DB00555,10007617,147,6900,99,3387,0.019550636,0.728863893,0.559147956,0.953487361,0.060725374,DB0055510007617_,2.801393641,-0.316268269,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,lamotrigine,DB00555
,356999,DB01016,10010144,40,1061,29,1199,0.086053378,1.558399113,0.934949837,2.62641644,0.188437792,DB0101610010144_,1.668987342,0.443659085,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,glyburide,DB01016
,357004,DB00956,10038669,58,5756,36,3431,0.831333257,0.960371402,0.621440332,1.502048676,0.911819568,DB0095610038669_,0.092313151,-0.040435192,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydrocodone,DB00956
,357005,DB01067,10010144,54,4307,204,4619,3.87158124080333e-19,0.283939251,0.205705857,0.386145622,3.72082314129856e-17,DB0106710010144_,37.83000166,-1.258994969,male,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,glipizide,DB01067
,357023,DB01192,10010144,83,685,44,510,0.088775618,1.40409181,0.944328574,2.110870102,0.193212046,DB0119210010144_,1.643967008,0.339390695,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,oxymorphone,DB01192
,357073,DB00343,10074903,42,8694,24,5071,1,1.020731881,0.603210209,1.764547723,1,DB0034310074903_,0,0.0205199,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,357075,DB00907,10074903,31,1107,72,1739,0.079747637,0.676450786,0.426069881,1.052054003,0.178017919,DB0090710074903_,1.725871065,-0.390895582,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,cocaine,DB00907
,357084,DB09053,10053762,188,2097,264,3788,0.012679923,1.286287397,1.052997401,1.569058348,0.043008459,DB0905310053762_,3.146358454,0.251760082,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ibrutinib,DB09053
,357085,DB09054,10053762,23,401,30,551,0.886908975,1.053369285,0.574977744,1.907312266,0.95298528,DB0905410053762_,0.048155821,0.05199387,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,idelalisib,DB09054
,357086,DB09054,10061818,41,383,86,495,0.016258526,0.616446877,0.404233715,0.927943145,0.052501322,DB0905410061818_,2.946916923,-0.483783129,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,idelalisib,DB09054
,357087,DB00683,10013654,22,1562,35,1603,0.11086402,0.645160143,0.358799658,1.136829419,0.227376777,DB0068310013654_,1.481146827,-0.438256709,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,midazolam,DB00683
,357097,DB00327,10076308,32,6106,28,4234,0.42981165,0.792501261,0.461451652,1.368251452,0.598297404,DB0032710076308_,0.513667318,-0.232561183,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydromorphone,DB00327
,357098,DB00813,10076308,85,10487,115,10053,0.018798716,0.708557354,0.528185797,0.947401365,0.058848836,DB0081310076308_,2.832783217,-0.344524272,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,357099,DB01075,10076308,143,19805,72,11025,0.520827702,1.105632583,0.826381204,1.490241896,0.679857778,DB0107510076308_,0.385871653,0.100417644,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,357101,DB00193,10061599,37,19283,13,8689,0.541001372,1.28244312,0.66587226,2.630770147,0.696388893,DB0019310061599_,0.361847021,0.248766947,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,357106,DB08910,10061599,40,16704,20,17468,0.006401004,2.091418163,1.193551523,3.777948902,0.024929676,DB0891010061599_,3.691696365,0.737842383,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pomalidomide,DB08910
,357110,DB00184,10070863,60,1234,37,945,0.346177558,1.241724325,0.803139676,1.942089245,0.515589753,DB0018410070863_,0.662443882,0.216500998,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,nicotine,DB00184
,357161,DB00571,10074903,58,5065,10,2599,0.000677727,2.97581303,1.504825065,6.541301144,0.003987925,DB0057110074903_,5.52448429,1.090517289,female,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,propranolol,DB00571
,357178,DB00046,10012607,45,5414,30,4662,0.297130822,1.291617307,0.794557663,2.127146362,0.463011837,DB0004610012607_,0.77000266,0.25589516,NA,10012607,Diabetes mellitus inadequate control,10027433,Metabolism and nutrition disorders,Metab,insulin lispro,DB00046
,357189,DB00480,10042682,329,67099,274,67388,0.022301907,1.205898077,1.023786016,1.421305316,0.06729487,DB0048010042682_,2.69867127,0.187224582,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,357199,DB01015,10070863,80,9807,69,9312,0.565982028,1.100875146,0.786747176,1.543865149,0.717457385,DB0101510070863_,0.332041727,0.096105451,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,sulfamethoxazole,DB01015
,357200,DB09027,10011906,58,5121,91,7061,0.453912704,0.878851444,0.619763252,1.237598665,0.621459771,DB0902710011906_,0.475684099,-0.129139401,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,357213,DB06228,10003445,35,15877,19,16057,0.029172023,1.86294236,1.036366998,3.449034185,0.082864497,DB0622810003445_,2.490548577,0.622157152,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,357221,DB00907,10010144,243,895,227,1584,3.33786628513066e-10,1.894194019,1.545320107,2.322494598,1.00787840671636e-08,DB0090710010144_,18.41283321,0.638793428,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,cocaine,DB00907
,357241,DB00804,10061428,56,2944,24,875,0.140814602,0.693572362,0.42003379,1.177358198,0.270979708,DB0080410061428_,1.305711341,-0.365899701,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,dicyclomine,DB00804
,357250,DB00182,10010144,346,4848,197,2655,0.676088314,0.961888702,0.79986821,1.159134213,0.803737729,DB0018210010144_,0.218482271,-0.03885653,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,357270,DB01114,10070863,38,582,75,348,6.58915643080127e-09,0.303316426,0.195122414,0.465118613,1.53883586658029e-07,DB0111410070863_,15.68706945,-1.192978709,male,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,chlorpheniramine,DB01114
,357271,DB06700,10070863,57,2168,12,606,0.460303486,1.32758886,0.698676043,2.736691814,0.62774085,DB0670010070863_,0.465627858,0.28336441,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,desvenlafaxine,DB06700
,357272,DB01268,10008479,30,2113,36,3094,0.450345139,1.220168462,0.723424688,2.044594218,0.618056232,DB0126810008479_,0.481175836,0.198988933,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,357304,DB01104,10036790,62,15401,11,7275,0.001490817,2.662364972,1.38889567,5.611246659,0.007651296,DB0110410036790_,4.872880191,0.979214815,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sertraline,DB01104
,357386,DB00514,10074903,42,2124,29,1507,1,1.027561507,0.621976067,1.718902499,1,DB0051410074903_,0,0.027188526,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,dextromethorphan,DB00514
,357407,DB01142,10013654,53,1687,53,731,3.68492144074909e-05,0.433469152,0.287478225,0.653517757,0.000339972,DB0114210013654_,7.986645879,-0.835934647,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,doxepin,DB01142
,357420,DB00121,10000087,69,4154,8,460,0.847979503,0.955101906,0.454783011,2.314749969,0.923978827,DB0012110000087_,0.079066122,-0.045937237,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,biotin,DB00121
,357432,DB00758,10070863,31,8269,81,9993,0.000178976,0.462536081,0.295144529,0.708526628,0.00131279,DB0075810070863_,6.635600957,-0.771030712,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,357488,DB00213,10010144,115,18780,63,13358,0.109010642,1.29837296,0.945995179,1.795962703,0.224574396,DB0021310010144_,1.493548241,0.261111912,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,pantoprazole,DB00213
,357489,DB00268,10010144,39,2936,13,1532,0.18646081,1.565251664,0.814956329,3.205857507,0.332031867,DB0026810010144_,1.10252433,0.448046619,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,ropinirole,DB00268
,357491,DB00758,10065154,82,8218,63,10011,0.007144634,1.585505764,1.126268251,2.241288006,0.027233801,DB0075810065154_,3.60329638,0.46090345,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,clopidogrel,DB00758
,357493,DB14509,10010144,63,822,27,524,0.094383304,1.48703567,0.919609122,2.462020395,0.202346165,DB1450910010144_,1.597775359,0.396784655,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,lithium carbonate,DB14509
,357544,DB08895,10029223,50,28064,8,6638,0.402426745,1.478294444,0.694947821,3.612476742,0.572256544,DB0889510029223_,0.558167885,0.39088902,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,357548,DB00588,10039117,45,16479,14,8454,0.128852794,1.648951375,0.888232076,3.254802392,0.253962008,DB0058810039117_,1.370570599,0.500139556,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,357570,DB01202,10013654,35,6679,73,5645,6.36367933399364e-06,0.405253435,0.262391567,0.615429223,7.31240213999672e-05,DB0120210013654_,9.523353635,-0.903242642,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,levetiracetam,DB01202
,357572,DB00829,10007617,174,7878,122,4332,0.04281268,0.784295998,0.616732302,0.99987793,0.111336177,DB0082910007617_,2.195201031,-0.242968781,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,diazepam,DB00829
,357612,DB00335,10010144,232,8234,319,5146,2.11589045788193e-19,0.45454473,0.380753082,0.542012519,2.07910955833371e-17,DB0033510010144_,38.41200688,-0.788458954,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,atenolol,DB00335
,357613,DB00727,10010144,40,3803,19,4154,0.00243051,2.299349545,1.298310147,4.211196383,0.011405151,DB0072710010144_,4.473690197,0.832626276,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,nitroglycerin,DB00727
,357625,DB06228,10033295,35,15877,35,16041,1,1.010329919,0.61369631,1.66338149,1,DB0622810033295_,0,0.01027693,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,357627,DB00316,10002522,110,65364,42,36911,0.034234408,1.478968503,1.027494053,2.164374634,0.093876314,DB0031610002522_,2.365777176,0.391344887,NA,10002522,Anion gap,10022891,Investigations,Inv,acetaminophen,DB00316
,357649,DB00231,10007617,58,3238,21,2118,0.020089296,1.806397128,1.076180435,3.143545178,0.061973728,DB0023110007617_,2.781044721,0.591334325,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,temazepam,DB00231
,357654,DB00737,10010144,67,2734,34,898,0.047178217,0.64733558,0.419094537,1.016170875,0.119785504,DB0073710010144_,2.122052598,-0.434890448,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,meclizine,DB00737
,357666,DB01098,10042682,38,8111,13,7196,0.001893673,2.5930549,1.349917204,5.309186352,0.0093003,DB0109810042682_,4.677708661,0.952836679,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,357679,DB00334,10007617,93,2756,65,2747,0.035592066,1.426001293,1.022820471,1.998123046,0.096681389,DB0033410007617_,2.336334361,0.354874228,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,olanzapine,DB00334
,357680,DB00557,10007617,117,5870,82,2985,0.033665905,0.725566428,0.540523335,0.977856316,0.092706309,DB0055710007617_,2.378318745,-0.320802649,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,hydroxyzine,DB00557
,357752,DB06403,10013946,176,21295,37,6624,0.028896317,1.479584822,1.031917627,2.172723113,0.08224577,DB0640310013946_,2.498043322,0.391761523,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,ambrisentan,DB06403
,357770,DB01224,10034010,26,8082,39,5878,0.005201593,0.484882727,0.28304137,0.818005561,0.021120633,DB0122410034010_,3.857504835,-0.723848217,NA,10034010,Parkinsonism,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,357795,DB01065,10001053,34,4297,21,3030,0.68184186,1.14160322,0.64236212,2.074350107,0.807559819,DB0106510001053_,0.213738148,0.132433607,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,melatonin,DB01065
,357807,DB00868,10006451,113,2871,40,1606,0.012764791,1.580122236,1.08651622,2.339068569,0.043251374,DB0086810006451_,3.140726275,0.457502209,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,benzonatate,DB00868
,357809,DB01065,10006451,43,4288,15,3036,0.015979079,2.029474161,1.102936435,3.940116042,0.051782776,DB0106510006451_,2.9606977,0.707776725,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,melatonin,DB01065
,357813,DB00727,10007554,31,3812,37,4136,0.716311225,0.909079947,0.544180279,1.509186835,0.832187427,DB0072710007554_,0.18369759,-0.095322238,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,nitroglycerin,DB00727
,357824,DB00868,10007559,31,2953,22,1624,0.387551073,0.774990992,0.432849205,1.409803713,0.557568689,DB0086810007559_,0.584169574,-0.254903873,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,benzonatate,DB00868
,357850,DB01065,10015150,44,4287,19,3032,0.073139257,1.637745528,0.934308543,2.976538536,0.166750401,DB0106510015150_,1.791257187,0.493320618,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,melatonin,DB01065
,357999,DB00395,10038669,51,2133,31,705,0.009791638,0.543908894,0.33837361,0.886868487,0.034995833,DB0039510038669_,3.352526293,-0.608973521,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carisoprodol,DB00395
,358005,DB08820,10060795,29,4372,30,3515,0.35894157,0.777210423,0.449177853,1.342953419,0.528677528,DB0882010060795_,0.63737662,-0.252044151,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,ivacaftor,DB08820
,358009,DB00588,10070608,202,16322,157,8311,0.00010147,0.6551283,0.52826474,0.813689357,0.000807856,DB0058810070608_,7.121126873,-0.422924185,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,fluticasone propionate,DB00588
,358017,DB01068,10007617,315,13448,188,6652,0.049271565,0.828816968,0.687919879,1.00070225,0.123625725,DB0106810007617_,2.090496628,-0.187755935,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,clonazepam,DB01068
,358038,DB01174,10010144,49,890,53,739,0.21901719,0.767793443,0.503282367,1.16937029,0.37235968,DB0117410010144_,0.987895011,-0.264234536,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,phenobarbital,DB01174
,358081,DB00227,10028372,30,2437,25,1778,0.680815357,0.875532131,0.495815953,1.558393079,0.807023985,DB0022710028372_,0.21440189,-0.132923427,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,lovastatin,DB00227
,358113,DB00996,10037368,31,38922,22,22403,0.476811104,0.811068661,0.454603555,1.47055192,0.642157087,DB0099610037368_,0.442922322,-0.209402567,NA,10037368,Pulmonary congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,358129,DB00907,10007617,171,967,198,1613,0.001342893,1.440354295,1.148827802,1.804779444,0.007017483,DB0090710007617_,4.959350613,0.364889121,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,cocaine,DB00907
,358137,DB00476,10010144,471,16786,266,5911,3.9018662862557e-09,0.623537782,0.533758693,0.729599811,9.59855454695658e-08,DB0047610010144_,16.15906822,-0.472345919,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,358141,DB00829,10010071,66,7986,29,4425,0.33376942,1.261055354,0.801958668,2.027741103,0.502869643,DB0082910010071_,0.687424302,0.231948953,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,358185,DB00490,10007617,40,4030,10,1566,0.267361645,1.554288256,0.761464862,3.494164196,0.42963729,DB0049010007617_,0.844813938,0.441017727,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,buspirone,DB00490
,358188,DB01142,10010144,288,1452,189,595,1.05994773924652e-05,0.624537678,0.505416797,0.772762719,0.00011416,DB0114210010144_,9.077910363,-0.470743618,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,doxepin,DB01142
,358208,DB01270,10015958,54,1204,30,939,0.146539136,1.403610194,0.874296133,2.291626326,0.279084243,DB0127010015958_,1.276241596,0.339047627,NA,10015958,Eye pain,10015919,Eye disorders,Eye,ranibizumab,DB01270
,358216,DB00682,10010144,164,19295,134,16230,0.815587129,1.029471096,0.813535261,1.30454557,0.901141583,DB0068210010144_,0.104092894,0.029045172,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,warfarin,DB00682
,358218,DB00868,10010144,71,2913,21,1625,0.010992127,1.885811156,1.140246731,3.244157798,0.038391827,DB0086810010144_,3.259910685,0.63435805,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,benzonatate,DB00868
,358249,DB00950,10028810,95,4623,28,2028,0.074382137,1.488296831,0.964043717,2.364713295,0.168817584,DB0095010028810_,1.778936534,0.3976324,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,fexofenadine,DB00950
,358258,DB00950,10047942,56,4662,31,2025,0.291550049,0.784656648,0.495578348,1.263259145,0.456997616,DB0095010047942_,0.783077104,-0.242509047,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,fexofenadine,DB00950
,358263,DB00905,10037844,35,2683,16,909,0.332012345,0.741189988,0.397321457,1.441371003,0.500828951,DB0090510037844_,0.691490651,-0.299498293,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,bimatoprost,DB00905
,358266,DB00333,10007617,136,2935,122,3030,0.280015224,1.150809337,0.889674784,1.489835631,0.443880238,DB0033310007617_,0.812200486,0.140465466,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,methadone,DB00333
,358303,DB08904,10028411,57,11553,20,3539,0.590809233,0.873022469,0.515740647,1.536421327,0.737333487,DB0890410028411_,0.304714996,-0.135793986,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,certolizumab pegol,DB08904
,358311,DB00813,10061355,33,10539,23,10145,0.284262848,1.381117379,0.786212647,2.465180381,0.448732747,DB0081310061355_,0.801327787,0.322892867,NA,10061355,Poisoning,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,358317,DB06228,10061822,59,15853,36,16040,0.017811629,1.658184542,1.07668373,2.585855387,0.056407069,DB0622810061822_,2.875160799,0.505723354,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,358385,DB00480,10029223,146,67282,106,67556,0.011570012,1.382958711,1.069306761,1.793489464,0.040026029,DB0048010029223_,3.218225307,0.324225198,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,358411,DB00480,10047608,49,67379,46,67616,0.759195722,1.068995325,0.700004999,1.634886479,0.865765398,DB0048010047608_,0.14414131,0.066719259,NA,10047608,Vitamin B12 decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,358443,DB01234,10061218,33,31592,27,32861,0.368590639,1.271308589,0.741097043,2.198544333,0.538285042,DB0123410061218_,0.619367041,0.240046755,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,358474,DB00480,10054786,37,67391,34,67628,0.723446247,1.092042182,0.66673921,1.793754105,0.837386203,DB0048010054786_,0.177469901,0.088049505,NA,10054786,Skin burning sensation,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,358475,DB00188,10013946,35,7851,25,8803,0.092389061,1.569704842,0.912152759,2.738664044,0.199044831,DB0018810013946_,1.614225199,0.450887603,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,358489,DB01273,10039906,35,2005,32,1243,0.127955988,0.678174101,0.405451834,1.137779136,0.252776907,DB0127310039906_,1.375247969,-0.388351238,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,varenicline,DB01273
,358497,DB00669,10010144,34,6343,33,1064,1.84934655544762e-11,0.172890986,0.103397214,0.289371017,6.75139919582509e-10,DB0066910010144_,21.11610116,-1.75509402,male,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,sumatriptan,DB00669
,358521,DB00264,10066901,48,29559,41,24851,1,0.984261261,0.634971108,1.531952895,1,DB0026410066901_,0,-0.015863908,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,358526,DB01118,10066901,18,3045,35,4674,0.481638324,0.789446246,0.42010533,1.435193354,0.646224617,DB0111810066901_,0.436608132,-0.236423533,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,358529,DB00868,10002034,49,2935,27,1619,1,1.001085009,0.610887566,1.672538216,1,DB0086810002034_,0,0.001084421,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,benzonatate,DB00868
,358575,DB00028,10065484,98,13360,31,5584,0.207350031,1.3212504,0.873137014,2.050577389,0.358058481,DB0002810065484_,1.027058952,0.278578561,NA,10065484,Infusion site nodule,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,358592,DB09027,10003239,91,5088,105,7047,0.215226769,1.200329856,0.894267631,1.608608822,0.367651381,DB0902710003239_,1.000620123,0.182596399,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ledipasvir,DB09027
,358655,DB01238,10076309,101,5149,57,3445,0.326233035,1.185480779,0.845886877,1.675410039,0.494738742,DB0123810076309_,0.703725449,0.170148413,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole,DB01238
,358657,DB01183,10070863,27,532,51,497,0.00456456,0.494894599,0.293469213,0.818506887,0.018985592,DB0118310070863_,3.964074914,-0.703410471,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,naloxone,DB01183
,358663,DB09183,10028813,71,404,63,664,0.000980097,1.851333138,1.269793172,2.704179405,0.005415385,DB0918310028813_,5.218511244,0.615905995,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dasabuvir,DB09183
,358667,DB08889,10016322,67,3098,56,3829,0.035210034,1.478634958,1.017951005,2.154866782,0.095863194,DB0888910016322_,2.344833168,0.391119337,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,358676,DB06262,10020772,211,3589,246,4068,0.809387097,0.972197024,0.800527278,1.179933968,0.897289745,DB0626210020772_,0.108376453,-0.028196796,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,droxidopa,DB06262
,358677,DB00254,10022000,45,5890,33,3355,0.288077251,0.77677832,0.483689637,1.259172186,0.453080661,DB0025410022000_,0.79168511,-0.252600272,NA,10022000,Influenza,10021881,Infections and infestations,Infec,doxycycline,DB00254
,358683,DB00343,10013654,39,8697,89,5006,7.60938901002304e-14,0.252259421,0.168249583,0.372122649,3.96850774064396e-12,DB0034310013654_,26.25263098,-1.377297272,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,diltiazem,DB00343
,358710,DB00678,10013496,38,15561,15,10709,0.069556769,1.743388051,0.936329227,3.413433213,0.160510924,DB0067810013496_,1.829393278,0.555830376,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,losartan,DB00678
,358734,DB08889,10033425,51,3114,31,3854,0.001687058,2.035927914,1.274518989,3.300066998,0.008458804,DB0888910033425_,4.772547478,0.710951692,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,carfilzomib,DB08889
,358749,DB00924,10013911,34,10128,23,4228,0.08059819,0.617132264,0.352594374,1.098658677,0.179383863,DB0092410013911_,1.718227285,-0.482671911,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,358755,DB00327,10022000,41,6097,17,4245,0.081416964,1.679094404,0.931633168,3.15677587,0.180747035,DB0032710022000_,1.710656819,0.518254603,NA,10022000,Influenza,10021881,Infections and infestations,Infec,hydromorphone,DB00327
,358757,DB01307,10022437,31,2493,27,2042,0.894519383,0.940475458,0.541208823,1.643594201,0.955948677,DB0130710022437_,0.045051053,-0.061369725,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,insulin detemir,DB01307
,358774,DB00654,10008479,35,3781,27,2571,0.696853062,0.881473775,0.516955843,1.518204338,0.817604014,DB0065410008479_,0.20137715,-0.126160028,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,358831,DB00480,10007697,32,67396,28,67634,0.60825033,1.146891002,0.66884237,1.977197793,0.751004906,DB0048010007697_,0.286343095,0.137054805,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,358855,DB08889,10054112,28,3137,36,3849,0.899990789,0.954306498,0.559553245,1.612273785,0.956571579,DB0888910054112_,0.044399659,-0.046770383,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,carfilzomib,DB08889
,358864,DB00480,10028692,40,67388,14,67648,0.000346635,2.868301565,1.527409841,5.70808609,0.0022767,DB0048010028692_,6.085028063,1.053720065,female,10028692,Nail discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,358875,DB08910,10047461,60,16684,55,17433,0.513709284,1.139878376,0.776807432,1.675504288,0.673695227,DB0891010047461_,0.394977456,0.130921569,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,358895,DB00341,10017413,46,11359,20,5048,1,1.022145004,0.591926689,1.826088456,1,DB0034110017413_,0,0.021903364,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,cetirizine,DB00341
,358896,DB00471,10017413,58,14131,25,5440,0.624801188,0.893142151,0.549274594,1.491700122,0.764509819,DB0047110017413_,0.26852041,-0.113009527,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,montelukast,DB00471
,358897,DB00476,10017413,37,17220,26,6151,0.009650108,0.508316472,0.299373671,0.875085593,0.034592989,DB0047610017413_,3.36410425,-0.676651049,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,duloxetine,DB00476
,358899,DB00761,10017413,127,15180,62,8563,0.362695131,1.155508094,0.845310155,1.593790924,0.532250908,DB0076110017413_,0.630640268,0.144540155,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,potassium chloride,DB00761
,358905,DB01137,10017413,44,7728,40,5553,0.318128878,0.790432322,0.502564762,1.246431191,0.486109369,DB0113710017413_,0.721321641,-0.235175241,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,levofloxacin,DB01137
,358912,DB00341,10023547,43,11362,24,5044,0.35664633,0.795424912,0.471388722,1.371866941,0.526329321,DB0034110023547_,0.641828177,-0.228878826,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,cetirizine,DB00341
,358914,DB00497,10023547,60,19207,68,16307,0.109935256,0.749140509,0.520108372,1.076706412,0.225981314,DB0049710023547_,1.487302963,-0.288828718,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,oxycodone,DB00497
,358921,DB01075,10023547,49,19899,35,11062,0.256435422,0.778294219,0.493859192,1.23824455,0.417272113,DB0107510023547_,0.874016721,-0.250650653,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,diphenhydramine,DB01075
,358954,DB01137,10039101,43,7729,15,5578,0.015675101,2.068748435,1.125382394,4.013158726,0.051029374,DB0113710039101_,2.975353848,0.726943804,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,358967,DB00203,10007625,40,13838,27,8911,0.900427522,0.954025464,0.570679764,1.617784555,0.956698706,DB0020310007625_,0.044266769,-0.047064916,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,sildenafil,DB00203
,358968,DB00374,10007625,45,17671,14,5710,1,1.038645956,0.559376266,2.050463345,1,DB0037410007625_,0,0.037917899,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,treprostinil,DB00374
,359042,DB00571,10007617,130,4993,38,2571,0.001683816,1.76145452,1.214510683,2.60796108,0.008445588,DB0057110007617_,4.774111114,0.5661399,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,propranolol,DB00571
,359094,DB00787,10005734,24,16976,32,17216,0.349997056,0.760611437,0.428502469,1.333187413,0.519607982,DB0078710005734_,0.654680632,-0.273632647,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,acyclovir,DB00787
,359103,DB00480,10029216,195,67233,96,67566,4.52921658595228e-09,2.041288718,1.590312772,2.63504494,1.09926553981307e-07,DB0048010029216_,16.02345339,0.713581333,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,359114,DB00399,10040829,47,6945,26,4972,0.341079859,1.294118405,0.78395693,2.18002274,0.510275426,DB0039910040829_,0.672804649,0.257829695,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,zoledronic acid,DB00399
,359116,DB00761,10040829,73,15234,23,8602,0.013972368,1.792134456,1.107481065,3.003959532,0.04650379,DB0076110040829_,3.068221458,0.583407343,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,potassium chloride,DB00761
,359117,DB00787,10040829,108,16892,58,17190,6.6174433386287e-05,1.894871807,1.363787889,2.656167453,0.000559291,DB0078710040829_,7.488840664,0.639151188,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,acyclovir,DB00787
,359120,DB00115,10047461,64,18361,29,10443,0.33249501,1.255218185,0.797004618,2.020706052,0.501427542,DB0011510047461_,0.690296164,0.22730941,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,359146,DB05676,10021789,222,46907,123,25206,0.777535071,0.969847024,0.774204035,1.219636634,0.878740499,DB0567610021789_,0.129265648,-0.030616927,NA,10021789,Infection,10021881,Infections and infestations,Infec,apremilast,DB05676
,359178,DB01114,10010144,16,604,47,376,1.94456419629982e-08,0.212237625,0.110655662,0.387696655,4.08249759582593e-07,DB0111410010144_,14.71138669,-1.550048757,male,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,chlorpheniramine,DB01114
,359181,DB00497,10036000,36,19231,40,16335,0.251047051,0.764479051,0.473246958,1.230913157,0.410959191,DB0049710036000_,0.889261362,-0.268560657,NA,10036000,Poisoning deliberate,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,359200,DB05676,10043607,33,47096,21,25308,0.569083309,0.844450306,0.474109305,1.536164793,0.720103732,DB0567610043607_,0.328360005,-0.169069389,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,apremilast,DB05676
,359221,DB00836,10010071,35,5500,27,4048,0.897708848,0.95404867,0.560051745,1.641766337,0.956338178,DB0083610010071_,0.044643686,-0.047040592,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,359260,DB00343,10061623,49,8687,34,5061,0.427077804,0.839640114,0.530409286,1.343133508,0.595703791,DB0034310061623_,0.518011731,-0.174781915,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,359288,DB00080,10013709,29,611,42,871,1,0.984305046,0.584283937,1.638158592,1,DB0008010013709_,0,-0.015819424,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,daptomycin,DB00080
,359298,DB00480,10020989,44,67384,39,67623,0.584926806,1.132205005,0.718793808,1.789431673,0.732568728,DB0048010020989_,0.311198116,0.124167063,NA,10020989,Hypogeusia,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,359311,DB00182,10007617,124,5070,93,2759,0.025498844,0.725631913,0.547770673,0.96393781,0.074607571,DB0018210007617_,2.595513286,-0.320712399,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,amphetamine,DB00182
,359312,DB00182,10011906,124,5070,88,2764,0.068711242,0.768236768,0.577473051,1.02555874,0.15900647,DB0018210011906_,1.838810388,-0.263657302,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,359339,DB01192,10011906,68,700,52,502,0.771331732,0.937851144,0.631679308,1.398879128,0.874803873,DB0119210011906_,0.133755563,-0.064164038,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,oxymorphone,DB01192
,359400,DB00203,10011703,47,13831,27,8911,0.720802953,1.121539047,0.683741437,1.87413668,0.835393445,DB0020310011703_,0.179852474,0.114701891,NA,10011703,Cyanosis,10047065,Vascular disorders,Vasc,sildenafil,DB00203
,359473,DB08820,10011762,183,4218,134,3411,0.419633482,1.104340656,0.874729699,1.397110781,0.588568398,DB0882010011762_,0.530062135,0.099248465,NA,10011762,Cystic fibrosis,10010331,"Congenital, familial and genetic disorders",Cong,ivacaftor,DB08820
,359475,DB08820,10025482,126,4275,72,3473,0.020325383,1.421631742,1.051998416,1.933368907,0.062599179,DB0882010025482_,2.771003121,0.351805326,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ivacaftor,DB08820
,359557,DB01101,10054112,124,7465,97,3811,0.002019841,0.652623674,0.494829217,0.862851636,0.009805434,DB0110110054112_,4.624818579,-0.426754618,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,capecitabine,DB01101
,359584,DB00281,10061818,95,11363,52,5619,0.597501578,0.903421707,0.636594634,1.294494384,0.742638972,DB0028110061818_,0.297545258,-0.101565828,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,359606,DB00999,10010144,390,21040,359,11880,6.91015885307987e-11,0.613375516,0.529162943,0.711225947,2.31971296875101e-09,DB0099910010144_,19.88182238,-0.488777943,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,hydrochlorothiazide,DB00999
,359638,DB00121,10029331,60,4163,14,454,0.0169064,0.467483452,0.255656342,0.913353849,0.054170137,DB0012110029331_,2.915625498,-0.760391327,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,biotin,DB00121
,359642,DB00370,10035528,30,4511,22,3641,0.780833412,1.100665318,0.612802643,2.006295272,0.880700697,DB0037010035528_,0.127037442,0.095914831,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,mirtazapine,DB00370
,359647,DB01062,10050584,53,4433,14,1731,0.219432276,1.47822495,0.805951711,2.892658955,0.372803746,DB0106210050584_,0.986703147,0.39084201,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,oxybutynin,DB01062
,359650,DB00706,10010144,23,1052,113,15812,1.37089983535712e-05,3.058953975,1.855548512,4.845795158,0.000143277,DB0070610010144_,8.850732496,1.118073019,female,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,tamsulosin,DB00706
,359662,DB00480,10016338,129,67299,57,67605,9.15083845614855e-08,2.27356737,1.651883047,3.162799003,1.66918659833355e-06,DB0048010016338_,13.30317412,0.821350126,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,359693,DB00924,10007617,140,10022,56,4195,0.813346024,1.046433196,0.760622791,1.456493521,0.899775248,DB0092410007617_,0.105610271,0.045387426,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,cyclobenzaprine,DB00924
,359695,DB00213,10064848,731,18164,477,12944,0.144887497,1.092104458,0.969560946,1.230961714,0.276881591,DB0021310064848_,1.284165333,0.088106531,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,359698,DB00904,10064848,109,22960,67,14389,0.938219071,1.019554707,0.744730626,1.40464271,0.978051846,DB0090410064848_,0.022192598,0.01936597,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,ondansetron,DB00904
,359707,DB09033,10010264,32,2592,28,1641,0.230843503,0.723617811,0.420321359,1.252412376,0.386935018,DB0903310010264_,0.949498512,-0.323491912,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,vedolizumab,DB09033
,359729,DB00787,10013774,63,16937,32,17216,0.001329503,2.00112948,1.287117138,3.166980778,0.006963433,DB0078710013774_,4.967082691,0.693711761,NA,10013774,Dry eye,10015919,Eye disorders,Eye,acyclovir,DB00787
,359739,DB08815,10013573,35,1419,15,688,0.761741577,1.131242558,0.59723539,2.24545454,0.867966655,DB0881510013573_,0.141601982,0.123316638,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lurasidone,DB08815
,359849,DB09033,10028810,41,2583,21,1648,0.434885995,1.245572101,0.716255955,2.227258989,0.603313368,DB0903310028810_,0.505318536,0.219594943,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,vedolizumab,DB09033
,359868,DB11065,10013709,37,3149,36,2652,0.556291387,0.865588572,0.53040784,1.413816852,0.709708251,DB1106510013709_,0.342901307,-0.144345574,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pancrelipase amylase,DB11065
,359883,DB00678,10062355,109,15490,55,10669,0.066505268,1.364994346,0.977302148,1.925478973,0.155063487,DB0067810062355_,1.863920654,0.311150286,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,359984,DB01115,10010144,103,3497,114,2154,2.54264105742827e-05,0.556602018,0.419821106,0.737146671,0.00024503,DB0111510010144_,8.31412876,-0.585904804,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,nifedipine,DB01115
,360002,DB05351,10022437,47,2676,19,1112,1,1.027941676,0.588645351,1.863500922,1,DB0535110022437_,0,0.02755843,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,dexlansoprazole,DB05351
,360024,DB01306,10037153,30,4178,23,3843,0.581825018,1.199734667,0.67250331,2.16691017,0.7300706,DB0130610037153_,0.314614038,0.182100422,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,insulin aspart,DB01306
,360110,DB09140,10076309,31,3710,20,1778,0.296711317,0.74284588,0.408836481,1.379385483,0.462522652,DB0914010076309_,0.771059746,-0.297266685,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,oxygen,DB09140
,360173,DB04861,10010144,55,1910,19,1368,0.005769728,2.072870377,1.204624418,3.716285195,0.022950561,DB0486110010144_,3.774412911,0.728934302,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,nebivolol,DB04861
,360196,DB00480,10027599,60,67368,46,67616,0.174791815,1.309142932,0.876677475,1.966325452,0.31719444,DB0048010027599_,1.148240318,0.269372673,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,360204,DB00480,10036018,112,67316,143,67519,0.059932981,0.785581968,0.607754636,1.013331954,0.143342893,DB0048010036018_,1.942515666,-0.241330475,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,360237,DB00727,10049848,34,3809,32,4141,0.621217402,1.155087474,0.690077746,1.93767543,0.761528748,DB0072710049848_,0.272427355,0.144176076,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,360268,DB00188,10062237,35,7851,54,8774,0.166035215,0.724362991,0.45889775,1.13018384,0.305479692,DB0018810062237_,1.185871979,-0.322462644,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,bortezomib,DB00188
,360272,DB06262,10008479,93,3707,60,4254,0.000556249,1.778569687,1.267908058,2.511147084,0.003371614,DB0626210008479_,5.692363714,0.575809495,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,360274,DB06262,10020642,82,3718,41,4273,9.90212430043366e-06,2.298329665,1.556860638,3.439795064,0.000107686,DB0626210020642_,9.136289915,0.832182626,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,droxidopa,DB06262
,360276,DB06262,10033557,105,3695,34,4280,6.00645340469119e-12,3.576649461,2.402033406,5.447398913,2.38669127350428e-10,DB0626210033557_,22.15594293,1.274426457,female,10033557,Palpitations,10007541,Cardiac disorders,Card,droxidopa,DB06262
,360279,DB06262,10049848,57,3743,90,4224,0.054789896,0.714751773,0.50216588,1.010180818,0.13398013,DB0626210049848_,2.010063777,-0.335819967,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,360305,DB00126,10029410,40,10131,20,5925,0.595192302,1.169697504,0.667098316,2.114070151,0.740854745,DB0012610029410_,0.299950698,0.156745172,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,ascorbic acid,DB00126
,360334,DB01192,10007617,32,736,23,531,1,1.003777906,0.562039935,1.818613429,1,DB0119210007617_,0,0.003770788,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,oxymorphone,DB01192
,360337,DB00514,10007617,70,2096,26,1510,0.004357873,1.939257813,1.213725413,3.185849725,0.018307399,DB0051410007617_,4.000449965,0.662305329,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,dextromethorphan,DB00514
,360354,DB01075,10073317,37,19911,21,11076,1,0.98009457,0.558556168,1.763181505,1,DB0107510073317_,0,-0.020106212,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,360358,DB09122,10022061,112,1146,18,319,0.033225572,1.731571409,1.027793141,3.075254622,0.091771711,DB0912210022061_,2.388451184,0.549029325,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,peginterferon beta-1a,DB09122
,360371,DB00374,10046735,73,17643,16,5708,0.17463127,1.476041986,0.850095193,2.719559955,0.316963494,DB0037410046735_,1.148968672,0.389364171,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,treprostinil,DB00374
,360387,DB09027,10013709,123,5056,401,6751,1.31612105245802e-19,0.40959909,0.330804935,0.504263706,1.31787588052797e-17,DB0902710013709_,38.86792532,-0.892576427,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,360399,DB00956,10007617,100,5714,73,3394,0.204194096,0.813699259,0.593857514,1.119351067,0.354086411,DB0095610007617_,1.038214296,-0.206164442,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,hydrocodone,DB00956
,360413,DB00207,10039906,36,9044,23,5432,0.892953216,0.940104153,0.541421151,1.663595285,0.955415161,DB0020710039906_,0.045609309,-0.061764609,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,azithromycin,DB00207
,360527,DB00112,10015958,54,5879,18,4073,0.005571292,2.078265464,1.197777947,3.771546679,0.022306897,DB0011210015958_,3.802859351,0.731533634,NA,10015958,Eye pain,10015919,Eye disorders,Eye,bevacizumab,DB00112
,360536,DB00321,10021789,51,7396,21,2829,0.791827644,0.928939642,0.547729187,1.629030377,0.887301788,DB0032110021789_,0.11957012,-0.073711514,NA,10021789,Infection,10021881,Infections and infestations,Infec,amitriptyline,DB00321
,360541,DB01593,10037844,44,1089,19,679,0.234497012,1.443636202,0.817438141,2.641566008,0.391399159,DB0159310037844_,0.938027373,0.367165071,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,zinc,DB01593
,360560,DB00868,10007515,42,2942,14,1632,0.121574828,1.66400546,0.887620426,3.309650506,0.243687372,DB0086810007515_,1.411869136,0.509227624,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,benzonatate,DB00868
,360562,DB00557,10038669,73,5914,41,3026,0.620189061,0.911029224,0.611495669,1.373717703,0.760729361,DB0055710038669_,0.27347762,-0.093180303,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxyzine,DB00557
,360590,DB00175,10037884,34,8097,27,6079,0.89701591,0.945441433,0.553000003,1.631052767,0.956338178,DB0017510037884_,0.044643686,-0.056103336,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,pravastatin,DB00175
,360649,DB01101,10069339,35,7554,39,3869,0.001194345,0.459673377,0.282250211,0.746083824,0.006384009,DB0110110069339_,5.053959001,-0.777239092,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,capecitabine,DB01101
,360660,DB00295,10061355,35,14628,28,9574,0.440915616,0.818136543,0.483178382,1.397136791,0.609154396,DB0029510061355_,0.49568352,-0.200726033,NA,10061355,Poisoning,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,360665,DB00907,10061355,21,1117,37,1774,0.785903955,0.90141549,0.498599756,1.590164275,0.883799408,DB0090710061355_,0.123525156,-0.103788985,NA,10061355,Poisoning,10022117,"Injury, poisoning and procedural complications",Inj&P,cocaine,DB00907
,360666,DB01075,10061355,38,19910,43,11054,0.001580362,0.490641017,0.308437055,0.777806,0.008018227,DB0107510061355_,4.826038013,-0.712042545,NA,10061355,Poisoning,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,360687,DB00333,10061355,20,3051,34,3118,0.075973086,0.601204441,0.327121004,1.077598271,0.171426953,DB0033310061355_,1.763598032,-0.508820234,NA,10061355,Poisoning,10022117,"Injury, poisoning and procedural complications",Inj&P,methadone,DB00333
,360737,DB00635,10018870,36,33017,36,23758,0.188288714,0.719583821,0.440428263,1.175661793,0.334380707,DB0063510018870_,1.095475095,-0.32908226,NA,10018870,Blood urine present,10022891,Investigations,Inv,prednisone,DB00635
,360813,DB09270,10020642,35,3079,24,2344,0.791881543,1.110223341,0.639903674,1.95660207,0.887301788,DB0927010020642_,0.11957012,0.104561203,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,ubidecarenone,DB09270
,360820,DB08895,10056812,59,28055,7,6639,0.084887057,1.994497736,0.909330433,5.17852033,0.186592171,DB0889510056812_,1.678829949,0.690392257,NA,10056812,Body height decreased,10022891,Investigations,Inv,tofacitinib,DB08895
,360898,DB00210,10015150,185,700,62,287,0.236230771,1.223162692,0.88184879,1.712480693,0.393455445,DB0021010015150_,0.932787446,0.201439875,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,adapalene,DB00210
,360899,DB00210,10033474,63,822,19,330,0.312542215,1.330915111,0.771845053,2.393033742,0.479998371,DB0021010033474_,0.733972568,0.285866759,NA,10033474,Pain of skin,10040785,Skin and subcutaneous tissue disorders,Skin,adapalene,DB00210
,360978,DB01234,10005619,48,31577,36,32852,0.155607956,1.387156313,0.881538137,2.20054256,0.291570796,DB0123410005619_,1.232472436,0.327255834,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,dexamethasone,DB01234
,360986,DB00480,10037211,39,67389,34,67628,0.560637364,1.151124869,0.707939633,1.880064052,0.713227651,DB0048010037211_,0.337954623,0.140739611,NA,10037211,Psychomotor hyperactivity,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,360996,DB00480,10062519,35,67393,43,67619,0.428127498,0.816685655,0.507327409,1.30652816,0.59662971,DB0048010062519_,0.516458609,-0.202501014,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,361001,DB00907,10007515,137,1001,143,1668,0.000228238,1.596089185,1.236729138,2.059510284,0.001610099,DB0090710007515_,6.431459511,0.467556378,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,cocaine,DB00907
,361002,DB00907,10038669,121,1017,141,1670,0.009437591,1.408955498,1.081950392,1.832936237,0.033981793,DB0090710038669_,3.381930408,0.342848649,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cocaine,DB00907
,361009,DB09034,10013709,482,694,294,384,0.328496726,0.907183069,0.745881743,1.103679006,0.497102591,DB0903410013709_,0.698958854,-0.097411009,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,suvorexant,DB09034
,361080,DB00836,10070863,130,5405,182,3893,1.23483392866059e-08,0.514498417,0.406026029,0.650476819,2.72638469675293e-07,DB0083610070863_,15.11511921,-0.6645628,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,loperamide,DB00836
,361094,DB00316,10061309,171,65303,64,36889,0.004264552,1.50930889,1.125899907,2.044939736,0.017998356,DB0031610061309_,4.017474872,0.411651857,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acetaminophen,DB00316
,361096,DB06724,10061309,43,7886,7,3912,0.003715844,3.047053976,1.357356113,8.036841536,0.016069589,DB0672410061309_,4.13082669,1.114175214,female,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,calcium carbonate,DB06724
,361109,DB00915,10003549,70,1385,45,1006,0.562616638,1.129797236,0.758704335,1.697086354,0.71481153,DB0091510003549_,0.335736366,0.12203818,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,amantadine,DB00915
,361133,DB00019,10000059,39,18973,18,9511,0.88837166,1.086125863,0.606322993,2.01829444,0.95377715,DB0001910000059_,0.04732523,0.08261711,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,pegfilgrastim,DB00019
,361138,DB00019,10000060,43,18969,19,9510,0.688303771,1.134608811,0.646796239,2.062909438,0.812082689,DB0001910000060_,0.20815311,0.126287932,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,pegfilgrastim,DB00019
,361151,DB00019,10020937,56,18956,19,9510,0.176820954,1.478640745,0.864674178,2.636849293,0.319827882,DB0001910020937_,1.139972296,0.39112325,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,pegfilgrastim,DB00019
,361153,DB00377,10020937,40,1079,15,708,0.069137465,1.749270997,0.937062766,3.43592011,0.159788821,DB0037710020937_,1.833902205,0.559199128,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,palonosetron,DB00377
,361189,DB01413,10013710,33,1187,51,1608,0.577630271,0.876615593,0.544305717,1.394615591,0.726593021,DB0141310013710_,0.319388765,-0.131686703,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,cefepime,DB01413
,361216,DB00482,10010144,54,8205,21,3050,0.89634578,0.955864378,0.566721992,1.669160111,0.956301489,DB0048210010144_,0.044682051,-0.04513924,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,celecoxib,DB00482
,361217,DB01195,10010144,83,1156,39,705,0.210026214,1.297744686,0.865805142,1.97386145,0.361197267,DB0119510010144_,1.018331025,0.260627901,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,flecainide,DB01195
,361218,DB01183,10011906,31,528,30,518,1,1.013751603,0.584309104,1.761145189,1,DB0118310011906_,0,0.013657907,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,naloxone,DB01183
,361249,DB00410,10013573,71,1534,22,987,0.002294573,2.075947227,1.261587263,3.542230361,0.010878943,DB0041010013573_,4.52092619,0.730417544,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,mupirocin,DB00410
,361301,DB01062,10028810,57,4429,14,1731,0.143068203,1.591187894,0.872572107,3.100491593,0.274143086,DB0106210028810_,1.294105099,0.464480841,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,oxybutynin,DB01062
,361302,DB01377,10028810,64,3732,23,2647,0.004270046,1.973421911,1.204854002,3.339705487,0.018012863,DB0137710028810_,4.01666915,0.679769046,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,magnesium oxide,DB01377
,361594,DB00182,10038669,70,5124,76,2776,3.58657020860046e-05,0.499026558,0.35424295,0.702206888,0.000332064,DB0018210038669_,8.010182536,-0.695095963,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amphetamine,DB00182
,361692,DB06605,10029331,120,13953,95,12938,0.27297086,1.171262799,0.886408058,1.551382817,0.435947032,DB0660510029331_,0.830234528,0.158082483,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,361696,DB06605,10038428,67,14006,51,12982,0.310443406,1.217666784,0.832638705,1.790119704,0.477865171,DB0660510038428_,0.738426655,0.196936556,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,apixaban,DB06605
,361719,DB14500,10054112,115,7694,51,4022,0.365292016,1.178702757,0.838546941,1.676851875,0.534887012,DB1450010054112_,0.625699746,0.164414475,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,potassium,DB14500
,361724,DB00572,10070863,41,2861,25,2101,0.531218379,1.204303093,0.712521718,2.073485852,0.688090432,DB0057210070863_,0.373835008,0.185901054,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,atropine,DB00572
,361734,DB00490,10013654,58,4012,35,1541,0.046673115,0.63656036,0.409558564,1.002211831,0.118841697,DB0049010013654_,2.129962952,-0.451676034,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,buspirone,DB00490
,361752,DB00051,10001551,39,25692,27,11393,0.082364259,0.640540633,0.382018285,1.088647896,0.182288093,DB0005110001551_,1.702166915,-0.44544272,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,adalimumab,DB00051
,361753,DB00051,10003481,39,25692,21,11399,0.485113049,0.824000059,0.472715489,1.475018314,0.649246258,DB0005110003481_,0.431943192,-0.193584677,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,adalimumab,DB00051
,361804,DB00207,10013786,42,9038,19,5436,0.354249784,1.329519107,0.755503861,2.423042325,0.524087103,DB0020710013786_,0.646097381,0.284817303,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,azithromycin,DB00207
,361825,DB00787,10028735,49,16951,42,17206,0.462933598,1.184209945,0.767721539,1.833889147,0.630118048,DB0078710028735_,0.4618481,0.169075839,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,361855,DB00620,10047942,43,4785,23,3109,0.527443907,1.214673728,0.714295902,2.116226284,0.68502424,DB0062010047942_,0.378301054,0.194475504,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,triamcinolone,DB00620
,361860,DB13867,10047942,47,4503,25,2529,0.902033757,1.055852281,0.635028247,1.794788467,0.957195726,DB1386710047942_,0.043747388,0.05434829,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,fluticasone,DB13867
,361960,DB00480,10002953,58,67370,59,67603,1,0.986449465,0.674445137,1.442312264,1,DB0048010002953_,0,-0.013643181,NA,10002953,Aphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,361967,DB00480,10070488,59,67369,44,67618,0.140178671,1.345857444,0.895364144,2.036453697,0.270111896,DB0048010070488_,1.308918976,0.297031315,NA,10070488,Upper-airway cough syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,362005,DB08931,10046571,177,6400,26,2420,8.73628218064669e-07,2.573837404,1.693923366,4.06018195,1.2722059674144e-05,DB0893110046571_,11.27217309,0.945397939,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,riociguat,DB08931
,362024,DB00264,10014020,54,29553,11,24881,2.0664220340538e-06,4.132843346,2.135948563,8.770165187,2.72783773538506e-05,DB0026410014020_,10.50941621,1.418965632,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,metoprolol,DB00264
,362179,DB00273,10007617,74,8407,11,2182,0.104305253,1.745927545,0.919372597,3.655004694,0.217470442,DB0027310007617_,1.525692335,0.557285959,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,topiramate,DB00273
,362182,DB01202,10007617,30,6684,22,5696,0.676343454,1.162055074,0.647447476,2.116782206,0.80384645,DB0120210007617_,0.21834701,0.150190053,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,levetiracetam,DB01202
,362200,DB01012,10074903,445,10187,393,8292,0.256014777,0.921684927,0.80039116,1.061656634,0.416781148,DB0101210074903_,0.875194019,-0.081551842,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,cinacalcet,DB01012
,362305,DB01137,10070863,41,7731,55,5538,0.002484733,0.534034355,0.346921976,0.81622195,0.011609849,DB0113710070863_,4.455901514,-0.627295107,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,levofloxacin,DB01137
,362346,DB00704,10008531,34,4322,37,5157,0.720944485,1.096440655,0.666356129,1.799085909,0.835410838,DB0070410008531_,0.179831654,0.092069165,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,362353,DB00169,10066274,35,38656,20,18155,0.472815293,0.821917913,0.461377433,1.502988509,0.638788516,DB0016910066274_,0.44818184,-0.196114751,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,362354,DB00787,10066274,47,16953,51,17197,0.762300889,0.934807299,0.61496692,1.418374501,0.868285351,DB0078710066274_,0.141234873,-0.067414868,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,acyclovir,DB00787
,362369,DB00836,10017413,41,5494,31,4044,0.905389027,0.973511732,0.594614719,1.608620963,0.957832006,DB0083610017413_,0.043082876,-0.026845402,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,loperamide,DB00836
,362374,DB14513,10017413,56,7121,37,3527,0.184829674,0.749627069,0.485158512,1.1705323,0.329954359,DB1451310017413_,1.108800942,-0.288179438,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,magnesium,DB14513
,362448,DB00091,10015958,170,5340,29,2641,5.84326263658497e-09,2.898893264,1.940810171,4.472024971,1.38431868772092e-07,DB0009110015958_,15.79288755,1.064329031,female,10015958,Eye pain,10015919,Eye disorders,Eye,cyclosporine,DB00091
,362498,DB00768,10015946,49,1866,17,667,1,1.030300845,0.578244689,1.922326326,1,DB0076810015946_,0,0.029850842,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,olopatadine,DB00768
,362522,DB00091,10023644,75,5435,16,2654,0.001549179,2.288787871,1.318529385,4.216726329,0.007898396,DB0009110023644_,4.841095632,0.828022363,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,cyclosporine,DB00091
,362556,DB00555,10038669,66,6981,42,3444,0.217318509,0.775291924,0.517504882,1.172869821,0.370264872,DB0055510038669_,0.99353666,-0.254515645,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lamotrigine,DB00555
,362576,DB00091,10015915,48,5462,6,2664,0.000377783,3.901068318,1.6643336,11.1700282,0.002446725,DB0009110015915_,6.013005043,1.361250443,female,10015915,Eye discharge,10015919,Eye disorders,Eye,cyclosporine,DB00091
,362675,DB00231,10013654,31,3265,36,2103,0.016894167,0.554726402,0.330724945,0.925547807,0.054140842,DB0023110013654_,2.916166439,-0.589280255,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,temazepam,DB00231
,362709,DB00678,10033661,26,15573,46,10678,9.39883127749079e-05,0.387567352,0.229827449,0.640729411,0.000756309,DB0067810033661_,7.187060757,-0.947865634,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,losartan,DB00678
,362734,DB01075,10038683,44,19904,21,11076,0.606408536,1.165914762,0.678216361,2.065431932,0.749333538,DB0107510038683_,0.288571083,0.153505982,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,362760,DB01212,10013710,13,2006,77,1864,3.36070233012612e-13,0.156946428,0.079694647,0.285702731,1.60611019540664e-11,DB0121210013710_,24.85462079,-1.851850754,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ceftriaxone,DB01212
,362799,DB00331,10022687,31,24915,26,20726,1,0.991842422,0.569672912,1.73968904,1,DB0033110022687_,0,-0.008191033,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,362890,DB00190,10061428,50,3247,70,4604,1,1.012804186,0.688072632,1.481383904,1,DB0019010061428_,0,0.012722906,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,carbidopa,DB00190
,362928,DB00661,10027599,46,3482,10,1585,0.02978521,2.09365472,1.038806863,4.66552448,0.084237598,DB0066110027599_,2.474113926,0.738911209,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,verapamil,DB00661
,362986,DB00706,10037153,10,1065,73,15852,0.040489182,2.038859969,0.935722488,3.981438398,0.106617726,DB0070610037153_,2.238505496,0.712390813,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,tamsulosin,DB00706
,362992,DB11089,10037153,37,10138,14,8393,0.010936407,2.187824515,1.154293669,4.384174795,0.038243603,DB1108910037153_,3.263778981,0.782907678,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,docusate,DB11089
,362995,DB00864,10049414,33,6836,32,8360,0.382704654,1.261128405,0.750802331,2.120717869,0.552820149,DB0086410049414_,0.592722559,0.23200688,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,363022,DB00343,10017413,42,8694,20,5075,0.510697086,1.225869077,0.702932555,2.206624968,0.671102715,DB0034310017413_,0.398833076,0.203650043,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,diltiazem,DB00343
,363023,DB00999,10017413,111,21319,62,12177,0.936915558,1.022597694,0.742181607,1.419962244,0.976944837,DB0099910017413_,0.02332509,0.022346148,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,363026,DB00343,10028810,149,8587,47,5048,0.000131998,1.863579949,1.331634268,2.650035259,0.001010355,DB0034310028810_,6.897453183,0.622499341,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,diltiazem,DB00343
,363089,DB00695,10041807,35,28014,18,20510,0.265909683,1.42358227,0.784426528,2.670573086,0.427976242,DB0069510041807_,0.848687595,0.35317642,NA,10041807,Sputum discoloured,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,furosemide,DB00695
,363095,DB01273,10016173,39,2001,19,1256,0.41542633,1.288301534,0.722997653,2.371537466,0.584664208,DB0127310016173_,0.5367176,0.25332471,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,varenicline,DB01273
,363201,DB00051,10066044,47,25684,16,11404,0.413462383,1.304236601,0.725923697,2.465332513,0.582852585,DB0005110066044_,0.539820981,0.26561789,NA,10066044,Injection site papule,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,363217,DB00115,10043414,57,18368,13,10459,0.001695091,2.49659092,1.349451967,4.974060254,0.008485142,DB0011510043414_,4.769438698,0.914926169,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,363239,DB01050,10022081,51,18057,10,9361,0.002730125,2.643828565,1.326378868,5.843954154,0.012517239,DB0105010022081_,4.380648493,0.972228081,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,363256,DB00381,10013654,15,29345,49,22838,1.66187420986636e-07,0.238248645,0.124046725,0.432139772,2.87667853844829e-06,DB0038110013654_,12.75887421,-1.434440426,male,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,363265,DB00437,10010144,22,6899,85,11461,0.000190561,0.429990112,0.255847722,0.694514135,0.001383291,DB0043710010144_,6.583290095,-0.843993067,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,allopurinol,DB00437
,363321,DB06724,10021015,48,7881,27,3892,0.622769268,0.877964459,0.536012214,1.46578763,0.762932989,DB0672410021015_,0.270585077,-0.130149165,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,calcium carbonate,DB06724
,363484,DB00864,10065042,15,6854,48,8344,0.000561402,0.380467381,0.197719641,0.691867043,0.003395803,DB0086410065042_,5.685214929,-0.966354831,NA,10065042,Immune reconstitution inflammatory syndrome,10021428,Immune system disorders,Immun,tacrolimus,DB00864
,363490,DB00531,10018651,24,7228,32,6484,0.143024725,0.672825074,0.378776277,1.180158151,0.274089012,DB0053110018651_,1.294302363,-0.396269903,NA,10018651,Graft versus host disease,10021428,Immune system disorders,Immun,cyclophosphamide,DB00531
,363510,DB00697,10001949,48,6048,9,1797,0.266736813,1.58454097,0.767065364,3.680502747,0.42894935,DB0069710001949_,0.846416432,0.460294757,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,363546,DB00959,10014625,53,8025,34,4968,0.91198998,0.964990937,0.614742818,1.533395159,0.96056931,DB0095910014625_,0.040229139,-0.03563657,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,363590,DB00959,10028391,40,8038,20,4982,0.506192209,1.239561579,0.706832137,2.240906913,0.667030743,DB0095910028391_,0.404919143,0.214757751,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,methylprednisolone,DB00959
,363609,DB00316,10033474,54,65420,23,36930,0.286403735,1.325358963,0.799614174,2.26301922,0.451144351,DB0031610033474_,0.795967922,0.281683338,NA,10033474,Pain of skin,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,363775,DB00381,10019974,132,29228,62,22825,0.000822709,1.662604875,1.219837614,2.287284553,0.004687313,DB0038110019974_,5.362895755,0.508385574,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,amlodipine,DB00381
,363776,DB00863,10019974,55,10618,26,5814,0.562854858,1.158275402,0.713212567,1.926486677,0.715027788,DB0086310019974_,0.335433873,0.146932176,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,ranitidine,DB00863
,363838,DB00169,10021425,66,38625,15,18160,0.008485807,2.068688696,1.167792937,3.904215484,0.031223191,DB0016910021425_,3.466594158,0.726914927,NA,10021425,Immune system disorder,10021428,Immune system disorders,Immun,cholecalciferol,DB00169
,363856,DB00316,10018286,43,65431,13,36940,0.050805942,1.867392671,0.985490075,3.786087742,0.126509491,DB0031610018286_,2.067437944,0.624543164,NA,10018286,Gingival pain,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,363857,DB00480,10018286,64,67364,37,67625,0.007094141,1.736413614,1.140653389,2.678286972,0.027073611,DB0048010018286_,3.609195808,0.551821845,NA,10018286,Gingival pain,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,363902,DB00051,10062556,38,25693,15,11405,0.767423695,1.124527113,0.604034026,2.201372869,0.872234528,DB0005110062556_,0.136696937,0.117362603,NA,10062556,Grip strength decreased,10022891,Investigations,Inv,adalimumab,DB00051
,364024,DB01115,10016322,54,3546,18,2250,0.020031522,1.90335908,1.09552812,3.457738368,0.061842676,DB0111510016322_,2.7831616,0.643620262,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,364078,DB00410,10003988,50,1555,24,985,0.3324853,1.319531885,0.789953879,2.260342847,0.501427283,DB0041010003988_,0.690296681,0.277277041,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,mupirocin,DB00410
,364085,DB00635,10017367,33,33020,27,23767,0.694824004,0.879729956,0.512790985,1.52140596,0.816298847,DB0063510017367_,0.202974756,-0.128140286,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,364099,DB00787,10062189,39,16961,22,17226,0.028948314,1.8003824,1.040906473,3.189663339,0.082353637,DB0078710062189_,2.496732663,0.587999087,NA,10062189,Vitamin D decreased,10022891,Investigations,Inv,acyclovir,DB00787
,364110,DB01306,10028810,49,4159,23,3843,0.006397309,1.968399139,1.174033326,3.391941553,0.024920824,DB0130610028810_,3.692051511,0.677220592,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,insulin aspart,DB01306
,364128,DB00924,10005724,55,10107,14,4237,0.111601349,1.646868192,0.902290145,3.210639686,0.228461174,DB0092410005724_,1.476389001,0.498875419,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,cyclobenzaprine,DB00924
,364141,DB11089,10056812,30,10145,20,8387,0.480347932,1.240053786,0.680745593,2.305751854,0.645151907,DB1108910056812_,0.438269475,0.215154754,NA,10056812,Body height decreased,10022891,Investigations,Inv,docusate,DB11089
,364150,DB09027,10002855,63,5116,55,7097,0.014507904,1.588897652,1.086935006,2.328716651,0.047985436,DB0902710002855_,3.036857737,0.463040475,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ledipasvir,DB09027
,364163,DB00787,10049040,27,16973,32,17216,0.603173499,0.855834506,0.493042323,1.475253902,0.746917473,DB0078710049040_,0.291800578,-0.155678256,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,acyclovir,DB00787
,364184,DB00480,10040799,26,67402,32,67630,0.511788175,0.815251068,0.466602238,1.412178338,0.672126139,DB0048010040799_,0.397309249,-0.204259155,NA,10040799,Skin atrophy,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,364230,DB00535,10012735,62,1142,29,617,0.574163066,1.15502055,0.723034111,1.88325489,0.723954098,DB0053510012735_,0.323027289,0.144118136,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cefdinir,DB00535
,364231,DB00768,10012735,48,1867,16,668,0.886394364,1.073350459,0.594015546,2.039438429,0.952748725,DB0076810012735_,0.048404077,0.070785026,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,olopatadine,DB00768
,364260,DB01377,10029354,53,3743,36,2634,0.913976576,1.03602085,0.663703285,1.63380076,0.96151265,DB0137710029354_,0.039247558,0.035387269,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,magnesium oxide,DB01377
,364261,DB00316,10020039,14,65460,56,36897,9.15005734490046e-14,0.140917119,0.072421833,0.256559036,4.72513275659546e-12,DB0031610020039_,26.07812546,-1.959583367,male,10020039,Hiccups,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,364262,DB00480,10020039,14,67414,230,67432,1.41124059185776e-51,0.060877441,0.03273695,0.104277316,8.72810798987796e-49,DB0048010020039_,110.6601209,-2.798892605,male,10020039,Hiccups,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,364295,DB01060,10019974,35,8552,20,5061,1,1.035634372,0.580838145,1.895429557,1,DB0106010019974_,0,0.035014159,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,364299,DB00480,10000496,57,67371,50,67612,0.499921978,1.144076086,0.768636079,1.707659076,0.661587412,DB0048010000496_,0.413113162,0.1345974,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,364310,DB00999,10029366,37,21393,16,12223,0.393387056,1.321248142,0.716784448,2.545181116,0.563313291,DB0099910029366_,0.573919339,0.278576852,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,hydrochlorothiazide,DB00999
,364339,DB00476,10037884,43,17214,16,6161,0.882876771,0.961872755,0.530417481,1.830839013,0.951043643,DB0047610037884_,0.050195326,-0.038873109,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,duloxetine,DB00476
,364348,DB01076,10054236,80,25667,55,25528,0.038350469,1.446651291,1.01310258,2.078925122,0.102339296,DB0107610054236_,2.279461553,0.369251431,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,atorvastatin,DB01076
,364353,DB00480,10061173,55,67373,39,67623,0.099516365,1.415479489,0.922067132,2.191682566,0.210102227,DB0048010061173_,1.560161072,0.347468335,NA,10061173,Gastrointestinal motility disorder,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,364379,DB00399,10062355,46,6946,40,4958,0.380942088,0.820879584,0.524731937,1.289051181,0.550940207,DB0039910062355_,0.596128993,-0.197378851,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,zoledronic acid,DB00399
,364385,DB00788,10005191,34,9322,19,5042,0.886458155,0.967849021,0.536022352,1.798155297,0.952754032,DB0078810005191_,0.048398507,-0.032679174,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,naproxen,DB00788
,364388,DB00480,10043521,88,67340,55,67607,0.005669965,1.606328684,1.133867437,2.293053346,0.022620629,DB0048010043521_,3.788892981,0.473951255,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,364421,DB01390,10047895,21,1388,34,1483,0.17261586,0.660015946,0.362117356,1.17696036,0.314276365,DB0139010047895_,1.157482537,-0.415491284,NA,10047895,Weight decreased,10022891,Investigations,Inv,sodium bicarbonate,DB01390
,364427,DB13961,10062355,56,9401,43,6371,0.539373631,0.882587237,0.581782283,1.347145366,0.695210901,DB1396110062355_,0.363540025,-0.124897643,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,fish oil,DB13961
,364467,DB14513,10061822,50,7127,20,3544,0.447247376,1.24310005,0.725535057,2.208230148,0.615041188,DB1451310061822_,0.486066041,0.2176083,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,magnesium,DB14513
,364472,DB00787,10023644,39,16961,23,17225,0.041604469,1.722006978,1.002706624,3.021691626,0.108937937,DB0078710023644_,2.216976946,0.543490458,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,acyclovir,DB00787
,364478,DB00480,10086210,50,67378,49,67613,0.920255599,1.023971218,0.676431389,1.550702716,0.964711792,DB0048010086210_,0.035925884,0.023688419,NA,10086210,Superficial vein thrombosis,10047065,Vascular disorders,Vasc,lenalidomide,DB00480
,364480,DB00787,10016766,57,16943,58,17190,1,0.997085584,0.679058559,1.463585698,1,DB0078710016766_,0,-0.002918671,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,364482,DB00480,10018291,39,67389,17,67645,0.003146149,2.302953071,1.272375996,4.341699867,0.014064035,DB0048010018291_,4.264134437,0.834192243,NA,10018291,Gingival swelling,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,364490,DB00264,10016454,49,29558,17,24875,0.001160228,2.425581641,1.372286886,4.493727664,0.006230153,DB0026410016454_,5.078354461,0.886071348,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,364503,DB11365,10047899,34,1611,17,1531,0.033655265,1.90030562,1.027606916,3.643131877,0.09269616,DB1136510047899_,2.378428233,0.642014726,NA,10047899,Weight increased,10022891,Investigations,Inv,sennosides,DB11365
,364519,DB00207,10013946,42,9038,23,5432,0.797889566,1.097517818,0.644309551,1.914079317,0.890778357,DB0020710013946_,0.11565964,0.093051101,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,azithromycin,DB00207
,364522,DB01592,10013946,37,6239,18,3049,1,1.004550485,0.55656051,1.877661128,1,DB0159210013946_,0,0.004540163,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,iron,DB01592
,364528,DB00030,10037087,31,2175,20,1801,0.400054124,1.283391478,0.705810043,2.384567724,0.569941607,DB0003010037087_,0.562221367,0.249506166,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,insulin human,DB00030
,364529,DB01394,10048959,43,1397,39,1964,0.054036516,1.549824991,0.975455202,2.469218551,0.132544777,DB0139410048959_,2.020834753,0.438142015,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,colchicine,DB01394
,364545,DB13867,10050584,37,4513,13,2541,0.182482206,1.602399811,0.830610434,3.291473585,0.327029712,DB1386710050584_,1.117704249,0.471502387,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone,DB13867
,364551,DB00787,10037437,42,16958,62,17186,0.062240519,0.686537864,0.452390003,1.032778817,0.147632805,DB0078710037437_,1.913027133,-0.3760939,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,364570,DB00455,10023547,39,9362,28,5090,0.304969975,0.757315755,0.453621946,1.27945725,0.471767788,DB0045510023547_,0.751268389,-0.277974999,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,loratadine,DB00455
,364596,DB09270,10017413,33,3081,25,2343,1,1.003816301,0.577210505,1.76593357,1,DB0927010017413_,0,0.003809037,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,ubidecarenone,DB09270
,364599,DB00480,10017553,39,67389,34,67628,0.560637364,1.151124869,0.707939633,1.880064052,0.713227651,DB0048010017553_,0.337954623,0.140739611,NA,10017553,Furuncle,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,364613,DB00437,10052904,30,6891,35,11511,0.158689262,1.431730582,0.848300316,2.403061072,0.295752632,DB0043710052904_,1.218231878,0.35888391,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,allopurinol,DB00437
,364642,DB01118,10061623,21,3042,32,4677,1,1.008968647,0.55185074,1.808328152,1,DB0111810061623_,0,0.008928667,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,364734,DB00788,10013971,22,9334,30,5031,0.001128254,0.395289791,0.217038931,0.709444382,0.006085184,DB0078810013971_,5.101898337,-0.928136136,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,naproxen,DB00788
,364754,DB00476,10035226,66,17191,44,6133,0.002186511,0.535175396,0.359532391,0.803412485,0.010463803,DB0047610035226_,4.559833287,-0.625160743,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,duloxetine,DB00476
,364755,DB09570,10037844,128,3773,122,3813,0.653376605,1.060321931,0.817390283,1.375919881,0.787503919,DB0957010037844_,0.238886932,0.058572571,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ixazomib,DB09570
,364817,DB00480,10048886,47,67381,20,67642,0.000894512,2.359221688,1.370748512,4.203601249,0.005025059,DB0048010048886_,5.293318052,0.858331771,NA,10048886,Onychoclasis,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,364861,DB00480,10027940,35,67393,40,67622,0.644409045,0.877974619,0.541392793,1.417813724,0.780476932,DB0048010027940_,0.247850094,-0.130137593,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,364866,DB00480,10027951,21,67407,47,67615,0.002182955,0.44816124,0.254453807,0.764759666,0.010453447,DB0048010027951_,4.560823488,-0.802602202,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,364870,DB01234,10027951,15,31610,37,32851,0.003471703,0.421355433,0.214796217,0.786599456,0.015223443,DB0123410027951_,4.184918749,-0.864278542,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,364882,DB01275,10022437,47,3932,38,3311,0.912962185,1.041503748,0.662885451,1.645948164,0.961080181,DB0127510022437_,0.039697439,0.04066558,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,hydralazine,DB01275
,364887,DB00829,10061623,34,8018,21,4433,0.674780054,0.8951518,0.504088255,1.625139503,0.802790166,DB0082910061623_,0.219661912,-0.110761966,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,diazepam,DB00829
,364910,DB00091,10020937,56,5454,10,2660,0.002148007,2.730933842,1.377696204,6.013795864,0.010316163,DB0009110020937_,4.574043406,1.004643617,female,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,cyclosporine,DB00091
,364961,DB00787,10050819,35,16965,20,17228,0.042656332,1.777088428,0.997428938,3.250281518,0.111028537,DB0078710050819_,2.197968018,0.57497631,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,364975,DB00480,10049816,48,67380,45,67617,0.756732187,1.070450862,0.697644463,1.645018917,0.863836772,DB0048010049816_,0.146371449,0.068079926,NA,10049816,Muscle tightness,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,364992,DB00480,10016334,130,67298,81,67581,0.000707441,1.611671922,1.21164386,2.15464226,0.004130103,DB0048010016334_,5.489453017,0.477272101,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,365004,DB00230,10017413,35,19639,24,8627,0.118378115,0.640626115,0.37015515,1.126444198,0.238772877,DB0023010017413_,1.432242485,-0.445309276,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,pregabalin,DB00230
,365070,DB00480,10012434,69,67359,70,67592,1,0.989123135,0.698804041,1.399735796,1,DB0048010012434_,0,-0.010936451,NA,10012434,Dermatitis allergic,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,365086,DB00264,10048908,61,29546,43,24849,0.430739809,1.193081048,0.794138719,1.806536328,0.599205921,DB0026410048908_,0.512149965,0.176539077,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,metoprolol,DB00264
,365088,DB00695,10048908,70,27979,39,20489,0.175657119,1.314375049,0.87578102,1.998396218,0.318164236,DB0069510048908_,1.145187564,0.273361305,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,furosemide,DB00695
,365149,DB00927,10017413,50,7447,24,4992,0.192059493,1.396498811,0.840997018,2.3794028,0.339243585,DB0092710017413_,1.081036891,0.333968255,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,famotidine,DB00927
,365159,DB14500,10046735,64,7745,9,4064,3.13074210460123e-05,3.73106943,1.84501765,8.537619066,0.000294508,DB1450010046735_,8.130205982,1.316694903,female,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,potassium,DB14500
,365160,DB00480,10062544,51,67377,32,67630,0.037166419,1.599719458,1.008390286,2.572621344,0.09989461,DB0048010062544_,2.303639551,0.469828275,NA,10062544,Tooth fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,365179,DB00860,10037087,33,1850,22,1474,0.585029478,1.19507223,0.672873657,2.1616175,0.732628211,DB0086010037087_,0.311116921,0.178206627,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,prednisolone,DB00860
,365206,DB14500,10052904,49,7760,17,4056,0.154327967,1.506500923,0.851231194,2.794014055,0.289937147,DB1450010052904_,1.238091116,0.409789692,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,365233,DB00904,10018388,42,23027,16,14440,0.104600761,1.646089054,0.905861759,3.137632086,0.217921822,DB0090410018388_,1.523618896,0.498402204,NA,10018388,Glossodynia,10017947,Gastrointestinal disorders,Gastr,ondansetron,DB00904
,365298,DB00761,10066274,33,15274,22,8603,0.574662986,0.844880907,0.477648491,1.522127765,0.724362046,DB0076110066274_,0.322463948,-0.1685596,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,potassium chloride,DB00761
,365301,DB00318,10006451,46,4237,19,1820,1,1.039931746,0.595514519,1.88502461,1,DB0031810006451_,0,0.039155082,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,codeine,DB00318
,365306,DB00836,10037377,64,5471,41,4034,0.551576373,1.150930624,0.76395628,1.751335154,0.705570419,DB0083610037377_,0.348748698,0.140570854,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loperamide,DB00836
,365320,DB01068,10033557,116,13647,31,6809,0.001482063,1.866941222,1.245443277,2.875103183,0.007616035,DB0106810033557_,4.877499424,0.624301381,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,clonazepam,DB01068
,365322,DB00136,10048959,39,2053,20,1662,0.11299405,1.578429204,0.894537515,2.86801418,0.2305508,DB0013610048959_,1.467284052,0.456430178,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,calcitriol,DB00136
,365427,DB00571,10022086,66,5057,18,2591,0.014936916,1.878513578,1.099215068,3.369720937,0.049147754,DB0057110022086_,3.012924137,0.630480814,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,propranolol,DB00571
,365429,DB06724,10017413,67,7862,31,3888,0.829608824,1.068817218,0.687094872,1.696155492,0.910634524,DB0672410017413_,0.093613644,0.066552633,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,calcium carbonate,DB06724
,365480,DB00996,10074300,34,38919,17,22408,0.66604378,1.151541851,0.625556019,2.198411091,0.796884442,DB0099610074300_,0.227045601,0.141101785,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,gabapentin,DB00996
,365485,DB09027,10013573,129,5050,140,7012,0.052661172,1.279379276,0.996476203,1.641647557,0.130026669,DB0902710013573_,2.040015706,0.24637502,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ledipasvir,DB09027
,365490,DB00480,10052140,60,67368,36,67626,0.014201394,1.673032828,1.088618771,2.604470757,0.047119874,DB0048010052140_,3.055060413,0.514638044,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,lenalidomide,DB00480
,365494,DB01234,10018627,41,31584,84,32804,0.000307487,0.50695657,0.34005403,0.745203904,0.002058922,DB0123410018627_,6.18557281,-0.67932994,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,365501,DB00425,10062355,79,12616,48,7436,0.854407278,0.970051873,0.668440123,1.420796558,0.929230002,DB0042510062355_,0.073398991,-0.030405731,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,365502,DB14500,10062355,66,7743,49,4024,0.061137039,0.699993148,0.475401484,1.036845483,0.14552747,DB1450010062355_,1.927390416,-0.356684732,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,365672,DB00787,10060933,45,16955,39,17209,0.51277846,1.171125089,0.745292974,1.847599441,0.672926525,DB0078710060933_,0.396119131,0.157964902,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,365732,DB00413,10003988,56,2143,17,1190,0.034698541,1.82891769,1.041574829,3.373564456,0.094842319,DB0041310003988_,2.355539568,0.603724366,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pramipexole,DB00413
,365752,DB00254,10042674,43,5892,9,3379,0.003553879,2.739749199,1.315214589,6.40002497,0.015508211,DB0025410042674_,4.166385678,1.007866383,female,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,doxycycline,DB00254
,365795,DB08868,10013496,48,9154,21,2490,0.076876839,0.621771402,0.364418764,1.095421873,0.172983583,DB0886810013496_,1.754558585,-0.475182775,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,365800,DB00281,10019063,33,11425,22,5649,0.314909719,0.741647985,0.419184959,1.336647543,0.482478547,DB0028110019063_,0.728818821,-0.298880563,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,lidocaine,DB00281
,365801,DB00555,10019063,49,6998,40,3446,0.023041601,0.603238844,0.388341854,0.942082043,0.069000112,DB0055510019063_,2.673647144,-0.505442068,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,365836,DB01104,10028836,79,15384,19,7267,0.006483302,1.964029895,1.177682669,3.435952571,0.02519048,DB0110410028836_,3.681289124,0.674998431,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,365852,DB08868,10057040,52,9150,9,2502,0.272181592,1.579813694,0.770105502,3.651727423,0.435085452,DB0886810057040_,0.832212826,0.457306925,NA,10057040,Temperature intolerance,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,365868,DB00480,10043431,33,67395,22,67640,0.140160163,1.505440328,0.851648844,2.710680902,0.270086132,DB0048010043431_,1.309014363,0.409085432,NA,10043431,Thinking abnormal,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,365888,DB00480,10035737,29,67399,42,67620,0.153848438,0.69274533,0.416090718,1.138812912,0.289274022,DB0048010035737_,1.240380868,-0.367092837,NA,10035737,Pneumonia viral,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,365990,DB01137,10029410,20,7752,30,5563,0.013770303,0.478435096,0.257263212,0.87181436,0.045935962,DB0113710029410_,3.080506985,-0.737234717,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,levofloxacin,DB01137
,366048,DB06317,10035664,42,561,66,654,0.158587732,0.742023996,0.483251801,1.128897636,0.295605328,DB0631710035664_,1.218730065,-0.298373697,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,elotuzumab,DB06317
,366064,DB01069,10003553,50,6650,8,2387,0.034942375,2.243335337,1.053188619,5.48726777,0.095310571,DB0106910003553_,2.350614548,0.807963748,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,promethazine,DB01069
,366066,DB00497,10016334,42,19225,30,16345,0.480382235,1.190266586,0.727114289,1.970455636,0.645173606,DB0049710016334_,0.438235842,0.174177304,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,366110,DB01075,10057668,47,19901,17,11080,0.150581187,1.53924609,0.867113309,2.86085426,0.284750109,DB0107510057668_,1.256143294,0.431292745,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,366247,DB00480,10013496,71,67357,49,67613,0.044625123,1.454475508,0.996426086,2.138283926,0.114833947,DB0048010013496_,2.164268135,0.37464536,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,366280,DB00480,10006784,144,67284,124,67538,0.221540464,1.16567182,0.910227237,1.494569484,0.375399116,DB0048010006784_,0.979765509,0.153297591,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,366399,DB00169,10028164,65,38626,24,18151,0.36306032,1.272648522,0.785628326,2.126573913,0.532574062,DB0016910028164_,0.630033307,0.241100179,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,cholecalciferol,DB00169
,366478,DB00787,10017944,99,16901,62,17186,0.00263268,1.623667207,1.169390941,2.269471459,0.012154255,DB0078710017944_,4.410075971,0.484687299,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,366479,DB00836,10017944,41,5494,18,4057,0.06548066,1.68191486,0.943275947,3.115258688,0.153278043,DB0083610017944_,1.875501734,0.519932942,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,366483,DB00264,10043417,49,29558,50,24842,0.363873949,0.82364586,0.543721129,1.247094149,0.53346125,DB0026410043417_,0.628368845,-0.194014623,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,366493,DB00480,10048038,25,67403,34,67628,0.297532301,0.737752915,0.421898112,1.273665829,0.463431396,DB0048010048038_,0.769096918,-0.304146313,NA,10048038,Wound infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,366519,DB00193,10023547,50,19270,26,8676,0.537202208,0.865848469,0.528371872,1.450071686,0.69338113,DB0019310023547_,0.366175459,-0.144045364,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,tramadol,DB00193
,366528,DB00216,10025482,51,872,6,102,1,0.994271429,0.41238693,2.905935323,1,DB0021610025482_,0,-0.005745042,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,eletriptan,DB00216
,366709,DB00863,10023547,42,10631,26,5814,0.613348467,0.883450477,0.528581878,1.502530798,0.7550882,DB0086310023547_,0.280920716,-0.123920042,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,ranitidine,DB00863
,366710,DB06228,10023547,31,15881,45,16031,0.135311335,0.695406553,0.425185595,1.124038382,0.263124838,DB0622810023547_,1.335126691,-0.363258636,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,rivaroxaban,DB06228
,366748,DB01229,10043071,64,5677,53,2656,0.002661728,0.565023173,0.385257943,0.831608093,0.012262468,DB0122910043071_,4.401212091,-0.570888535,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,paclitaxel,DB01229
,366779,DB00904,10066274,34,23035,31,14425,0.159936654,0.686850255,0.409415213,1.156129077,0.29737108,DB0090410066274_,1.212774491,-0.37563898,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,ondansetron,DB00904
,366818,DB00230,10042128,49,19625,16,8635,0.346367683,1.347434629,0.752771447,2.540147438,0.515793697,DB0023010042128_,0.662048406,0.29820251,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,pregabalin,DB00230
,366820,DB00480,10040872,29,67399,42,67620,0.153848438,0.69274533,0.416090718,1.138812912,0.289274022,DB0048010040872_,1.240380868,-0.367092837,NA,10040872,Skin infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,366821,DB13867,10006451,77,4473,21,2533,0.002050242,2.076193673,1.264277567,3.551447746,0.009922776,DB1386710006451_,4.612922529,0.730536252,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,fluticasone,DB13867
,366833,DB00480,10028034,39,67389,32,67630,0.408692882,1.223104631,0.746589778,2.017070533,0.57808171,DB0048010028034_,0.548040054,0.201392406,NA,10028034,Mouth ulceration,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,366865,DB00188,10020642,32,7854,24,8804,0.142038932,1.49456138,0.852260519,2.654296782,0.272652102,DB0018810020642_,1.299558648,0.401832773,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,bortezomib,DB00188
,366867,DB00115,10001480,43,18382,33,10439,0.191170313,0.740010788,0.458944233,1.203042429,0.33804781,DB0011510001480_,1.084567945,-0.301090514,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,cyanocobalamin,DB00115
,366874,DB01373,10001480,44,22676,26,7355,0.017728977,0.548927863,0.330350464,0.929306883,0.056216439,DB0137310001480_,2.878546053,-0.599788243,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,calcium,DB01373
,366949,DB01114,10012735,41,579,11,412,0.003455322,2.650003381,1.318230562,5.787193271,0.015163726,DB0111410012735_,4.188849155,0.974560916,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,chlorpheniramine,DB01114
,366950,DB00218,10029331,91,1351,89,861,0.006940313,0.651768688,0.474952252,0.894514538,0.02661795,DB0021810029331_,3.626169461,-0.428065553,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,moxifloxacin,DB00218
,366953,DB09153,10029331,35,7764,33,5666,0.325152639,0.774029694,0.466546314,1.286799263,0.493563155,DB0915310029331_,0.706104455,-0.256145042,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,sodium chloride,DB09153
,366983,DB00327,10028810,39,6099,13,4249,0.022833179,2.08986835,1.090426198,4.272316501,0.068500839,DB0032710028810_,2.680909283,0.737101074,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,hydromorphone,DB00327
,366998,DB00575,10038669,33,5211,22,3807,0.785500892,1.095868268,0.618884638,1.976335816,0.883669115,DB0057510038669_,0.12367259,0.091546988,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonidine,DB00575
,367000,DB00341,10010144,95,11310,38,5030,0.637620857,1.111837771,0.75452225,1.667807083,0.77486138,DB0034110010144_,0.25507113,0.106014296,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,cetirizine,DB00341
,367009,DB05259,10016326,57,11213,12,2716,0.761522079,1.15052784,0.609330248,2.359373244,0.867834721,DB0525910016326_,0.141753996,0.140220828,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,367149,DB00480,10047482,70,67358,58,67604,0.289715586,1.211300694,0.842926274,1.746532775,0.454881679,DB0048010047482_,0.787717941,0.191694736,NA,10047482,Viral upper respiratory tract infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,367167,DB00390,10022000,56,4089,24,3277,0.009224922,1.869808842,1.137226825,3.161530787,0.033370845,DB0039010022000_,3.400072663,0.625836202,NA,10022000,Influenza,10021881,Infections and infestations,Infec,digoxin,DB00390
,367200,DB01164,10051283,22,6502,34,7902,0.421022099,0.786396143,0.43768986,1.385672405,0.590043767,DB0116410051283_,0.527558564,-0.240294615,NA,10051283,Fluid imbalance,10027433,Metabolism and nutrition disorders,Metab,calcium chloride,DB01164
,367229,DB00381,10031252,47,29313,28,22859,0.29498225,1.30898351,0.802665243,2.171403323,0.46087621,DB0038110031252_,0.774625798,0.269250889,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,amlodipine,DB00381
,367266,DB00215,10028735,50,11053,14,5262,0.081946503,1.700199758,0.924345028,3.333154826,0.181623493,DB0021510028735_,1.705819452,0.530745749,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,citalopram,DB00215
,367269,DB01012,10061623,610,10022,453,8232,0.120162438,1.106035764,0.974366708,1.256241386,0.241584037,DB0101210061623_,1.420537889,0.100782239,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,367270,DB08910,10016454,34,16710,20,17468,0.041341855,1.777072845,0.993543357,3.259625394,0.108417704,DB0891010016454_,2.221763879,0.574967541,NA,10016454,Femur fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pomalidomide,DB08910
,367330,DB00669,10073317,124,6253,26,1071,0.351043991,0.816898761,0.528886582,1.306018949,0.520780636,DB0066910073317_,0.652426369,-0.202240107,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,sumatriptan,DB00669
,367331,DB00863,10073317,43,10630,8,5832,0.002950041,2.948755412,1.369222878,7.266370839,0.013317619,DB0086310073317_,4.31866739,1.081383187,female,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,367333,DB11065,10000060,51,3135,22,2666,0.008852,1.971126314,1.170621959,3.42264587,0.032284558,DB1106510000060_,3.433166238,0.678605112,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,pancrelipase amylase,DB11065
,367335,DB09122,10016173,47,1211,14,323,0.749017582,0.895470565,0.477403023,1.784098375,0.857606649,DB0912210016173_,0.153609735,-0.110405928,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,peginterferon beta-1a,DB09122
,367337,DB00190,10046571,141,3156,129,4545,0.000258806,1.573946289,1.22527549,2.023295209,0.001788309,DB0019010046571_,6.326485046,0.453586026,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,carbidopa,DB00190
,367539,DB00722,10076229,93,25310,18,26014,5.13878897839316e-14,5.310025896,3.181037038,9.351149598,2.72599532385599e-12,DB0072210076229_,26.6281875,1.669596712,female,10076229,Intestinal angioedema,10017947,Gastrointestinal disorders,Gastr,lisinopril,DB00722
,367554,DB08895,10040984,154,27960,27,6619,0.156226973,1.350228462,0.891970064,2.116840227,0.292386769,DB0889510040984_,1.229677802,0.300273809,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,tofacitinib,DB08895
,367578,DB05676,10038683,62,47067,46,25283,0.105980414,0.724043832,0.486312585,1.084722862,0.220160846,DB0567610038683_,1.513396881,-0.322903347,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,367579,DB00338,10011732,39,33635,21,22251,0.510288545,1.22855504,0.705002755,2.198943478,0.670754092,DB0033810011732_,0.399352689,0.205838715,NA,10011732,Cyst,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,367592,DB09035,10021114,55,4671,71,6619,0.649510928,1.097697926,0.755997561,1.586610436,0.784287431,DB0903510021114_,0.242979705,0.093215193,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,nivolumab,DB09035
,367634,DB01024,10024384,48,2163,34,2086,0.18194918,1.361407021,0.85545332,2.188158286,0.326321473,DB0102410024384_,1.11987227,0.308518739,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,mycophenolic acid,DB01024
,367713,DB01156,10038669,125,13497,87,6241,0.004680687,0.664373328,0.500446254,0.885369981,0.019394948,DB0115610038669_,3.942742669,-0.408911046,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,367716,DB01156,10061355,32,13590,32,6296,0.002752476,0.463292094,0.27452011,0.781829957,0.012601035,DB0115610061355_,4.373976313,-0.76939755,NA,10061355,Poisoning,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,367729,DB00381,10016970,57,29303,13,22874,1.03422796344917e-05,3.422505027,1.850399355,6.818111491,0.000111733,DB0038110016970_,9.099396875,1.230372747,female,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,367750,DB00695,10010144,202,27847,141,20387,0.70110473,1.048841172,0.841001711,1.310948962,0.820482419,DB0069510010144_,0.197862796,0.047685909,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,furosemide,DB00695
,367751,DB00794,10010144,41,795,22,587,0.243913917,1.375746418,0.790748602,2.453051251,0.40235196,DB0079410010144_,0.910428052,0.318996433,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,primidone,DB00794
,367752,DB00904,10010144,139,22930,20,14436,5.09434235066374e-13,4.375359527,2.725398061,7.388006947,2.36790077254105e-11,DB0090410010144_,24.46643221,1.475988694,female,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,367873,DB09053,10025197,20,2265,54,3998,0.113900552,0.653789813,0.369692678,1.11354541,0.23202046,DB0905310025197_,1.460929721,-0.424969365,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,ibrutinib,DB09053
,367895,DB01234,10001052,37,31588,63,32825,0.016339364,0.610308265,0.395166017,0.930580432,0.052680795,DB0123410001052_,2.94350432,-0.493791098,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,367948,DB01592,10005619,46,6230,18,3049,0.504567077,1.250639398,0.709824664,2.295791536,0.665548334,DB0159210005619_,0.407144016,0.223654939,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,iron,DB01592
,367982,DB01026,10037844,51,1059,33,1035,0.075066449,1.510139715,0.947152529,2.437034313,0.169950183,DB0102610037844_,1.772249927,0.412202173,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ketoconazole,DB01026
,367993,DB08904,10017577,45,11565,11,3548,0.635377689,1.255016658,0.638236213,2.693635096,0.773416276,DB0890410017577_,0.256937855,0.227148846,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,368002,DB00318,10037660,43,4240,18,1821,1,1.025996878,0.577537046,1.895322568,1,DB0031810037660_,0,0.025664704,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,codeine,DB00318
,368077,DB00281,10022061,83,11375,12,5659,8.33083869720286e-06,3.440795689,1.866631482,6.931635435,9.26686818264821e-05,DB0028110022061_,9.286479987,1.23570275,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,368082,DB06228,10013786,40,15872,20,16056,0.00947084,2.023130666,1.154543329,3.654576445,0.034080503,DB0622810013786_,3.379029812,0.704646146,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,rivaroxaban,DB06228
,368097,DB01270,10025482,42,1216,18,951,0.03467605,1.82435476,1.019952595,3.390288822,0.094800559,DB0127010025482_,2.355979977,0.601226368,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ranibizumab,DB01270
,368100,DB00295,10017413,47,14616,26,9576,0.549686938,1.184307401,0.71803382,1.993595243,0.704033191,DB0029510017413_,0.350929777,0.169158132,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,morphine,DB00295
,368103,DB09079,10013573,39,618,18,859,9.90939630423435e-05,3.009447991,1.662745348,5.64581921,0.000790736,DB0907910013573_,7.142546234,1.10175667,female,10013573,Dizziness,10029205,Nervous system disorders,Nerv,nintedanib,DB09079
,368110,DB00370,10001488,18,4523,32,3631,0.006484919,0.451607105,0.238248263,0.8307631,0.02519472,DB0037010001488_,3.681120829,-0.794942714,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,mirtazapine,DB00370
,368139,DB00073,10016322,45,7361,28,6379,0.195529306,1.392704865,0.848962119,2.321240318,0.343697984,DB0007310016322_,1.06799196,0.331247802,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,368178,DB00046,10007515,26,5433,37,4655,0.056544108,0.602113604,0.349510827,1.02319934,0.137026865,DB0004610007515_,1.987578279,-0.50730914,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,insulin lispro,DB00046
,368190,DB09052,10029350,80,849,65,994,0.037931173,1.440689935,1.011759466,2.057706804,0.10149211,DB0905210029350_,2.287774213,0.365122121,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,blinatumomab,DB09052
,368195,DB09052,10037660,130,799,154,905,0.748330354,0.956154824,0.736627614,1.239799189,0.857074656,DB0905210037660_,0.154230251,-0.04483543,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,blinatumomab,DB09052
,368203,DB09073,10002034,371,19889,14,776,1,1.033936883,0.604753184,1.91906293,1,DB0907310002034_,0,0.033373733,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,palbociclib,DB09073
,368206,DB09073,10069339,49,20211,7,783,0.004784169,0.271239028,0.121671955,0.712055166,0.019745918,DB0907310069339_,3.92480849,-1.304754826,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,palbociclib,DB09073
,368227,DB00820,10075192,37,11878,15,5801,0.65755155,1.204642046,0.644735461,2.364704598,0.790692277,DB0082010075192_,0.234846417,0.186182465,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,tadalafil,DB00820
,368238,DB01112,10013709,34,1111,26,553,0.125152131,0.651057331,0.375037205,1.142131557,0.248846308,DB0111210013709_,1.39091981,-0.429157575,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cefuroxime,DB01112
,368260,DB01248,10048959,31,2669,19,1355,0.548193606,0.82837384,0.45146188,1.558157375,0.70266837,DB0124810048959_,0.352870233,-0.188290729,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,docetaxel,DB01248
,368297,DB00115,10040831,53,18372,15,10457,0.015878603,2.011061957,1.116119833,3.843677287,0.051539774,DB0011510040831_,2.965401466,0.698662919,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,368351,DB01281,10000059,110,8822,19,1779,0.635070319,1.167459561,0.710929501,2.018150289,0.773227836,DB0128110000059_,0.257181531,0.154830073,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,abatacept,DB01281
,368373,DB06605,10067482,60,14013,41,12992,0.135663438,1.356770223,0.896367733,2.071939962,0.263653022,DB0660510067482_,1.333121351,0.305107039,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,368381,DB01098,10007554,27,8122,38,7171,0.080455982,0.627356515,0.367969909,1.056039982,0.179173557,DB0109810007554_,1.719400353,-0.466240295,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,rosuvastatin,DB01098
,368450,DB00203,10076309,274,13604,161,8777,0.372162685,1.09801855,0.898791056,1.344922892,0.541835392,DB0020310076309_,0.612793029,0.093507237,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,368490,DB00455,10010144,70,9331,19,5099,0.005248877,2.013179308,1.197009855,3.544805863,0.021266549,DB0045510010144_,3.85061992,0.699715218,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,loratadine,DB00455
,368531,DB00310,10047700,31,913,21,760,0.483990836,1.228665201,0.677427597,2.269768634,0.648215366,DB0031010047700_,0.433532283,0.205928378,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,chlorthalidone,DB00310
,368537,DB00480,10021654,57,67371,61,67601,0.782500641,0.93759114,0.641681448,1.368219293,0.881650708,DB0048010021654_,0.125959325,-0.06444131,NA,10021654,Increased appetite,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,368551,DB00410,10010774,44,1561,23,986,0.525970617,1.208252664,0.708915961,2.110207433,0.683909976,DB0041010010774_,0.379928983,0.189175236,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,mupirocin,DB00410
,368553,DB00972,10010774,41,2463,18,1161,0.888562429,1.073668893,0.600126752,1.994596943,0.953826126,DB0097210010774_,0.047273882,0.071081655,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,azelastine,DB00972
,368555,DB00868,10012174,36,2948,19,1627,1,1.045697225,0.581949621,1.936682319,1,DB0086810012174_,0,0.044683864,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,benzonatate,DB00868
,368569,DB09065,10016256,22,730,67,1870,0.549092785,0.841195915,0.490843183,1.39157785,0.703529313,DB0906510016256_,0.351645736,-0.172930691,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cobicistat,DB09065
,368572,DB09027,10022998,31,5148,63,7089,0.092742984,0.677612247,0.425316975,1.059331831,0.199627345,DB0902710022998_,1.611302924,-0.389180062,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,ledipasvir,DB09027
,368574,DB09027,10028813,468,4711,456,6696,4.08789647476865e-08,1.458681591,1.272492665,1.672238411,8.04269152988727e-07,DB0902710028813_,14.03333186,0.377533008,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ledipasvir,DB09027
,368677,DB09027,10013710,43,5136,85,7067,0.05849383,0.696101198,0.469892148,1.018005803,0.140679984,DB0902710013710_,1.961267583,-0.36226023,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,368800,DB00571,10020993,35,5088,30,2579,0.047128671,0.591382921,0.351848174,0.99966396,0.11970596,DB0057110020993_,2.122716877,-0.525291551,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,propranolol,DB00571
,368870,DB00567,10037153,41,4478,20,2061,0.889974309,0.94352205,0.538686716,1.704397226,0.954386794,DB0056710037153_,0.046686245,-0.058135544,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,cephalexin,DB00567
,368872,DB05676,10044034,54,47075,18,25311,0.083579572,1.613011476,0.931022245,2.923112858,0.184418809,DB0567610044034_,1.690545972,0.478102914,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,368917,DB00654,10037660,50,3766,36,2562,0.825355414,0.944876863,0.601464429,1.497602759,0.907661321,DB0065410037660_,0.096883965,-0.056700664,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,368918,DB00175,10068319,54,8077,30,6076,0.223681787,1.354037703,0.849969026,2.194678162,0.378113493,DB0017510068319_,0.972560882,0.30309102,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,368949,DB00005,10069868,2235,125847,857,41562,0.000280197,0.861314672,0.795097076,0.933679076,0.001910003,DB0000510069868_,6.260650307,-0.149295369,NA,10069868,Device issue,10077536,Product issues,Prod,etanercept,DB00005
,368960,DB00586,10043607,35,7074,17,2788,0.536786517,0.811410809,0.441707415,1.547265733,0.69303176,DB0058610043607_,0.366679451,-0.208980806,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,diclofenac,DB00586
,368987,DB14500,10022000,104,7705,45,4028,0.339322299,1.208148435,0.841903688,1.758207461,0.50838387,DB1450010022000_,0.676518467,0.189088969,NA,10022000,Influenza,10021881,Infections and infestations,Infec,potassium,DB14500
,368998,DB01190,10048799,13,4921,50,2235,6.62061826056721e-15,0.118123311,0.058735144,0.221278959,4.00513120780228e-13,DB0119010048799_,28.54602987,-2.136026196,male,10048799,Acute generalised exanthematous pustulosis,10040785,Skin and subcutaneous tissue disorders,Skin,clindamycin,DB01190
,369125,DB00213,10048908,43,18852,22,13399,0.256663487,1.389172262,0.812402861,2.439730532,0.417531889,DB0021310048908_,0.873394356,0.328708075,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,pantoprazole,DB00213
,369162,DB13867,10042772,46,4504,26,2528,1,0.993031527,0.599406727,1.677727688,1,DB1386710042772_,0,-0.006992866,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,fluticasone,DB13867
,369181,DB01104,10037162,45,15418,10,7276,0.029339693,2.123561357,1.054292214,4.728831506,0.083246313,DB0110410037162_,2.485951443,0.753094564,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,sertraline,DB01104
,369189,DB00181,10013946,45,9811,11,5860,0.005402656,2.443329094,1.243018003,5.242313256,0.021755469,DB0018110013946_,3.827890107,0.893361492,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,baclofen,DB00181
,369220,DB05676,10017577,128,47001,40,25289,0.002039656,1.72175509,1.198301941,2.521990738,0.00988155,DB0567610017577_,4.617085938,0.543344172,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,369268,DB00331,10061520,42,24904,27,20725,0.333673908,1.294517763,0.779383272,2.18417619,0.502772718,DB0033110061520_,0.687617065,0.258138242,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,369307,DB00230,10067585,32,19642,20,8631,0.228695412,0.703068164,0.389709597,1.297854643,0.384312269,DB0023010067585_,0.956299856,-0.352301431,NA,10067585,Type 2 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,pregabalin,DB00230
,369345,DB01005,10033371,38,1057,26,841,0.609920011,1.162780926,0.681579846,2.011976491,0.752152172,DB0100510033371_,0.284816618,0.150814486,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,hydroxyurea,DB01005
,369390,DB00215,10000381,96,11007,18,5258,0.000110227,2.547589998,1.527249814,4.485028242,0.00086668,DB0021510000381_,7.050840746,0.935147813,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,369479,DB00996,10063746,90,38863,55,22370,0.730396646,0.941911626,0.665810967,1.342956387,0.84315587,DB0099610063746_,0.170603439,-0.059843824,NA,10063746,Accidental death,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,369511,DB01069,10064848,68,6632,33,2362,0.172027327,0.733915758,0.476088456,1.151803993,0.313492962,DB0106910064848_,1.159978368,-0.309361028,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,promethazine,DB01069
,369519,DB09027,10000081,47,5132,60,7092,0.69489627,1.082494299,0.721546142,1.615532908,0.816346666,DB0902710000081_,0.202916179,0.079267914,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ledipasvir,DB09027
,369521,DB09027,10028411,71,5108,86,7066,0.416756004,1.142028438,0.820298623,1.585706497,0.585955151,DB0902710028411_,0.534512026,0.132806013,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ledipasvir,DB09027
,369569,DB00048,10050584,20,214,59,790,0.396444267,1.251112733,0.697414253,2.163734024,0.566027084,DB0004810050584_,0.56911335,0.224033342,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,collagenase clostridium histolyticum,DB00048
,369592,DB00153,10042458,39,7384,16,3423,0.772102728,1.129933816,0.616030204,2.169046775,0.875243998,DB0015310042458_,0.133252576,0.122159061,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,ergocalciferol,DB00153
,369594,DB01373,10042458,56,22664,11,7370,0.154093925,1.65540761,0.857575801,3.50609644,0.289663077,DB0137310042458_,1.239036833,0.504047269,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,calcium,DB01373
,369599,DB00370,10035598,30,4511,27,3636,0.690392607,0.895601532,0.513528832,1.568814371,0.81323667,DB0037010035598_,0.206733104,-0.110259684,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mirtazapine,DB00370
,369675,DB06403,10023232,170,21301,32,6629,0.007710896,1.653206025,1.126783966,2.496301856,0.028929619,DB0640310023232_,3.542889341,0.502716448,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,369693,DB00423,10040753,50,2417,10,1030,0.031375497,2.130354711,1.062488819,4.730834104,0.087734568,DB0042310040753_,2.433439296,0.756288497,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,methocarbamol,DB00423
,369850,DB00820,10013786,43,11872,19,5797,0.787352122,1.105071733,0.629684061,2.009925517,0.884765643,DB0082010013786_,0.122432479,0.099910249,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,tadalafil,DB00820
,369871,DB08932,10029331,96,19347,21,6576,0.070030698,1.553742706,0.960542985,2.626381566,0.161335456,DB0893210029331_,1.824269503,0.44066667,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,369875,DB08932,10052267,43,19400,7,6590,0.072945864,2.086741765,0.93002032,5.500848985,0.166432189,DB0893210052267_,1.793167328,0.735603885,NA,10052267,Catheter site inflammation,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,369886,DB09027,10020772,51,5128,52,7100,0.132707664,1.357876787,0.902848223,2.041434775,0.259598196,DB0902710020772_,1.348620245,0.305922294,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ledipasvir,DB09027
,369899,DB04854,10013573,23,758,42,1444,0.894950389,1.043186688,0.594096455,1.790135657,0.955976233,DB0485410013573_,0.045022227,0.042280152,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,febuxostat,DB04854
,369949,DB08931,10016326,39,6538,11,2435,0.523540031,1.320400528,0.661896236,2.863587123,0.681717293,DB0893110016326_,0.383140234,0.277935121,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,370215,DB00864,10058080,46,6823,78,8314,0.084865329,0.718634094,0.487263076,1.0492692,0.186558935,DB0086410058080_,1.679008086,-0.330402961,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,370241,DB00480,10058920,58,67370,32,67630,0.006008366,1.819475709,1.161903735,2.895977498,0.023691854,DB0048010058920_,3.742624003,0.598548387,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,370244,DB00091,10003988,87,5423,14,2656,2.35635973029742e-05,3.043217806,1.715923492,5.807768424,0.000229651,DB0009110003988_,8.378949134,1.112915444,female,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclosporine,DB00091
,370285,DB09072,10076309,348,6123,192,2343,0.000114711,0.693593376,0.576020138,0.837038389,0.000896972,DB0907210076309_,7.016486224,-0.365869404,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium oxybate,DB09072
,370299,DB00390,10010144,32,4113,56,3245,0.000318904,0.450879932,0.281831518,0.710282877,0.002121051,DB0039010010144_,6.155843478,-0.7965542,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,digoxin,DB00390
,370364,DB08910,10048865,27,16717,48,17440,0.027761236,0.586839696,0.351899439,0.960053068,0.07969682,DB0891010048865_,2.529525591,-0.533003586,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,pomalidomide,DB08910
,370381,DB06605,10039101,66,14007,24,13009,4.63756978149137e-05,2.553818989,1.578039805,4.264248676,0.000414269,DB0660510039101_,7.788996116,0.937589882,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,370383,DB06605,10041349,88,13985,72,12961,0.475288222,1.132723849,0.819330251,1.57033616,0.640927093,DB0660510041349_,0.444839567,0.124625218,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,370385,DB06605,10068319,65,14008,22,13011,2.02550926976018e-05,2.743974538,1.668454422,4.677849584,0.000201898,DB0660510068319_,8.507747778,1.009407431,female,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,370429,DB08820,10054112,380,4021,364,3181,0.01319196,0.825893963,0.708042804,0.96346188,0.044401135,DB0882010054112_,3.114490254,-0.191288888,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,ivacaftor,DB08820
,370527,DB06605,10019304,43,14030,34,12999,0.496166118,1.171760805,0.729445668,1.895786495,0.658473513,DB0660510019304_,0.417830982,0.158507579,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,apixaban,DB06605
,370609,DB00635,10023676,29,33024,35,23759,0.042322898,0.59613205,0.351386005,1.004205785,0.110341269,DB0063510023676_,2.20417727,-0.517293075,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,prednisone,DB00635
,370618,DB01104,10007554,26,15437,33,7253,0.000205436,0.370198146,0.212458465,0.638750834,0.00147357,DB0110410007554_,6.520067239,-0.993716888,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,sertraline,DB01104
,370663,DB00480,10047924,64,67364,48,67614,0.131160654,1.338274086,0.906021163,1.988394476,0.257472576,DB0048010047924_,1.356842065,0.291380789,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,370665,DB09183,10005364,44,431,74,653,0.621589872,0.900910171,0.593590339,1.354582814,0.761860987,DB0918310005364_,0.271991172,-0.104349726,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,dasabuvir,DB09183
,370683,DB01142,10037844,45,1695,12,772,0.111639003,1.707640346,0.882269654,3.567464632,0.228519917,DB0114210037844_,1.476131909,0.535112503,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,doxepin,DB01142
,370753,DB01611,10010144,52,11861,10,2351,1,1.030707752,0.517204052,2.278061799,1,DB0161110010144_,0,0.030245704,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,hydroxychloroquine,DB01611
,370776,DB09073,10016256,4024,16236,91,699,9.78958010889903e-10,1.903670049,1.523796688,2.402001253,2.72295357843821e-08,DB0907310016256_,17.41896358,0.643783628,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,palbociclib,DB09073
,370778,DB09073,10022437,361,19899,7,783,0.069826456,2.02925459,0.970149279,5.100598841,0.160981709,DB0907310022437_,1.826464529,0.707668529,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,palbociclib,DB09073
,370782,DB09073,10029354,1360,18900,28,762,0.000183351,1.958221089,1.337550046,2.978706811,0.001340391,DB0907310029354_,6.614794277,0.672036453,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,palbociclib,DB09073
,370948,DB01181,10028813,43,530,53,867,0.193604669,1.326912499,0.853224302,2.054066589,0.341181906,DB0118110028813_,1.075339494,0.282854814,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ifosfamide,DB01181
,370996,DB00836,10047513,47,5488,16,4059,0.006804576,2.172434134,1.207640288,4.111135917,0.026206342,DB0083610047513_,3.641753821,0.775848259,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,loperamide,DB00836
,371027,DB01307,10033425,58,2466,48,2021,1,0.990285463,0.660660588,1.49033179,1,DB0130710033425_,0,-0.009762031,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin detemir,DB01307
,371041,DB08868,10040753,137,9065,16,2495,0.00047344,2.356629256,1.396914617,4.24744651,0.002951699,DB0886810040753_,5.825374329,0.857232317,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,fingolimod,DB08868
,371201,DB00110,10035664,19,512,37,651,0.167416723,0.653146359,0.350336996,1.181403163,0.307440427,DB0011010035664_,1.179473943,-0.425954041,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,palivizumab,DB00110
,371219,DB01039,10010264,67,2906,26,3025,8.77877960828659e-06,2.682053195,1.676698618,4.408643536,9.68957921299446e-05,DB0103910010264_,9.241874465,0.986582619,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,fenofibrate,DB01039
,371225,DB00421,10003246,40,8863,13,5239,0.063959046,1.818725489,0.951849557,3.709637416,0.150574431,DB0042110003246_,1.89329776,0.598135975,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,spironolactone,DB00421
,371229,DB01015,10003246,34,9853,24,9357,0.293769043,1.345327387,0.77401949,2.37317248,0.45951674,DB0101510003246_,0.777579906,0.296637394,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfamethoxazole,DB01015
,371398,DB00318,10003239,44,4239,10,1829,0.07304016,1.898294696,0.938697859,4.23985801,0.166578312,DB0031810003239_,1.79228974,0.640955955,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,codeine,DB00318
,371439,DB01248,10020937,46,2654,12,1362,0.035763425,1.966931905,1.021167205,4.092736619,0.09702654,DB0124810020937_,2.332770734,0.67647492,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,docetaxel,DB01248
,371471,DB01248,10037087,54,2646,10,1364,0.001907581,2.783102628,1.397508324,6.149518963,0.009362483,DB0124810037087_,4.671044722,1.023566358,female,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,docetaxel,DB01248
,371477,DB00112,10048959,56,5877,39,4052,1,0.990003707,0.644849529,1.533517193,1,DB0011210048959_,0,-0.010046591,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,bevacizumab,DB00112
,371579,DB01202,10001760,37,6677,15,5703,0.016937031,2.106676864,1.12730568,4.136592333,0.054239497,DB0120210001760_,2.914345912,0.74511176,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,levetiracetam,DB01202
,371711,DB00019,10027175,32,18980,19,9510,0.5548565,0.843896202,0.463693049,1.576703269,0.708324581,DB0001910027175_,0.344852843,-0.169725775,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,pegfilgrastim,DB00019
,371752,DB00853,10037844,47,1774,31,2235,0.005581841,1.909783623,1.18258864,3.123715777,0.022341814,DB0085310037844_,3.801295273,0.646989949,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,temozolomide,DB00853
,371887,DB00377,10061428,81,1038,54,669,0.855167533,0.966759387,0.666913358,1.410522888,0.929825999,DB0037710061428_,0.072757809,-0.033805639,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,palonosetron,DB00377
,371942,DB00958,10013700,54,4540,14,2571,0.007385453,2.184088734,1.193580534,4.266512614,0.027947973,DB0095810013700_,3.577410611,0.781198686,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,carboplatin,DB00958
,371951,DB00316,10018388,54,65420,20,36933,0.115835053,1.524284424,0.897477606,2.688781617,0.23494328,DB0031610018388_,1.448411156,0.42152507,NA,10018388,Glossodynia,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,371979,DB01234,10038743,42,31583,27,32861,0.053866689,1.618477397,0.974528363,2.730436599,0.132257803,DB0123410038743_,2.023002208,0.481485829,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,371986,DB01234,10040742,32,31593,28,32860,0.52093849,1.18868519,0.693120067,2.049443416,0.679934862,DB0123410040742_,0.385758277,0.172847814,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,372023,DB00773,10070863,39,2284,28,2799,0.035228077,1.706717631,1.020156277,2.889487593,0.095905749,DB0077310070863_,2.344389346,0.534572012,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,etoposide,DB00773
,372154,DB00186,10033553,47,16854,13,9995,0.015314822,2.143989436,1.140519865,4.321703385,0.050130771,DB0018610033553_,2.993120274,0.762668316,NA,10033553,Palmar-plantar erythrodysaesthesia syndrome,10040785,Skin and subcutaneous tissue disorders,Skin,lorazepam,DB00186
,372170,DB00019,10037087,56,18956,23,9506,0.474407434,1.220951424,0.738741043,2.080481584,0.640077413,DB0001910037087_,0.446166152,0.199630411,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,pegfilgrastim,DB00019
,372208,DB00012,10053762,354,1292,288,1025,0.787801345,0.975150864,0.814860483,1.16751887,0.88508114,DB0001210053762_,0.122075954,-0.025163088,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,darbepoetin alfa,DB00012
,372222,DB08881,10061428,32,591,40,771,0.903150385,1.043649494,0.626299814,1.726846244,0.957326661,DB0888110061428_,0.043610607,0.0427237,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,vemurafenib,DB08881
,372485,DB11365,10029331,32,1613,26,1522,0.598262458,1.161278358,0.667024096,2.03923729,0.743094301,DB1136510029331_,0.296932323,0.149521431,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,sennosides,DB11365
,372563,DB11365,10053762,58,1587,47,1501,0.487343812,1.167112147,0.775287444,1.764842283,0.6511988,DB1136510053762_,0.428940306,0.154532448,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sennosides,DB11365
,372570,DB00316,10067868,36,65438,16,36937,0.472658107,1.270056837,0.68693349,2.451549788,0.638658219,DB0031610067868_,0.448385836,0.239061653,NA,10067868,Skin mass,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,372618,DB00377,10033775,36,1083,20,703,0.677210598,1.168288877,0.652348928,2.148597515,0.804245873,DB0037710033775_,0.217850245,0.15554018,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,palonosetron,DB00377
,372620,DB00531,10033775,40,7212,26,6490,0.217368882,1.384409006,0.823249514,2.365653563,0.37032382,DB0053110033775_,0.993377466,0.325273338,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,372639,DB00341,10062352,31,11374,25,5043,0.029194105,0.549841114,0.313791185,0.972324685,0.082918262,DB0034110062352_,2.48989995,-0.598125927,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,cetirizine,DB00341
,372689,DB00874,10010774,73,3262,27,1949,0.036386778,1.615288812,1.021798319,2.623230018,0.098326971,DB0087410010774_,2.319456912,0.479513772,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,guaifenesin,DB00874
,372761,DB11089,10036018,20,10155,31,8376,0.033626355,0.532164129,0.287225284,0.964662404,0.092643858,DB1108910036018_,2.378992616,-0.630803324,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,docusate,DB11089
,372832,DB00927,10006002,45,7452,7,5009,4.63549441820394e-05,4.320680334,1.932079394,11.36508014,0.000414224,DB0092710006002_,7.789103822,1.463412874,female,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,famotidine,DB00927
,372834,DB01069,10006002,45,6655,13,2382,0.552776886,1.238938016,0.655404319,2.50784149,0.706536098,DB0106910006002_,0.347380985,0.214254574,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,promethazine,DB01069
,372911,DB01015,10049848,39,9848,36,9345,0.908564744,1.02800417,0.635968797,1.665874994,0.959033459,DB0101510049848_,0.041829315,0.027619224,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,sulfamethoxazole,DB01015
,372956,DB01109,10005750,52,4360,38,4232,0.203818512,1.328200217,0.855504133,2.079041065,0.353598415,DB0110910005750_,1.03959343,0.283824805,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,heparin,DB01109
,372977,DB01234,10022086,58,31567,34,32854,0.008739,1.775403285,1.142823418,2.797309128,0.031970022,DB0123410022086_,3.442956612,0.5740276,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,373050,DB00653,10011906,57,1035,69,753,0.006761252,0.601185495,0.410294522,0.878030044,0.026066225,DB0065310011906_,3.647114871,-0.508851748,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,magnesium sulfate,DB00653
,373101,DB00950,10047924,47,4671,17,2039,0.585701668,1.206810909,0.678292825,2.247555619,0.733075487,DB0095010047924_,0.310506599,0.187981267,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fexofenadine,DB00950
,373148,DB00741,10006451,42,4052,9,3165,0.000103075,3.644508071,1.745375907,8.528531451,0.000818896,DB0074110006451_,7.107553679,1.293221396,female,10006451,Bronchitis,10021881,Infections and infestations,Infec,hydrocortisone,DB00741
,373249,DB00572,10029354,29,2873,38,2088,0.017908905,0.554716299,0.328815315,0.926882332,0.056660517,DB0057210029354_,2.870677662,-0.58929847,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,atropine,DB00572
,373283,DB00619,10061818,43,2856,44,2450,0.448618531,0.838376279,0.535677238,1.311305486,0.616281911,DB0061910061818_,0.484050772,-0.176288259,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,373308,DB00012,10003239,57,1589,25,1288,0.012693114,1.847738463,1.128541244,3.104788695,0.043047353,DB0001210003239_,3.145454533,0.613962439,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,darbepoetin alfa,DB00012
,373352,DB00043,10023232,38,6375,12,2288,0.872170192,1.136504258,0.580124508,2.393282281,0.943900916,DB0004310023232_,0.057734081,0.12795711,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,omalizumab,DB00043
,373495,DB00043,10046306,60,6353,14,2286,0.184382623,1.54199467,0.849612299,2.994177057,0.329391187,DB0004310046306_,1.110509215,0.433076818,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,omalizumab,DB00043
,373511,DB01611,10013946,68,11845,10,2351,0.446293729,1.349638685,0.689598916,2.945214229,0.614099237,DB0161110013946_,0.487598741,0.299836916,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,hydroxychloroquine,DB01611
,373664,DB00479,10028813,48,567,21,378,0.126679164,1.52320385,0.878066465,2.72426517,0.251022085,DB0047910028813_,1.382214357,0.420815912,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,amikacin,DB00479
,373679,DB00673,10053762,42,625,22,319,1,0.974406068,0.557432024,1.74558072,1,DB0067310053762_,0,-0.025927154,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,aprepitant,DB00673
,373744,DB00531,10028810,42,7210,18,6498,0.008996148,2.102736238,1.183128476,3.885507951,0.032714313,DB0053110028810_,3.419942595,0.743239467,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,373958,DB00136,10053762,47,2045,44,1638,0.522061387,0.85562778,0.551930148,1.328586798,0.680758208,DB0013610053762_,0.384548091,-0.155919834,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,calcitriol,DB00136
,373977,DB00575,10061818,35,5209,27,3802,0.897494902,0.946179996,0.555339191,1.628314503,0.956338178,DB0057510061818_,0.044643686,-0.055322458,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,clonidine,DB00575
,374023,DB00177,10033775,43,4757,19,2831,0.295047384,1.346806893,0.766459441,2.452231187,0.460940296,DB0017710033775_,0.774486754,0.297736526,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,valsartan,DB00177
,374073,DB00377,10008469,42,1077,10,713,0.002297047,2.779147019,1.361126024,6.253224202,0.010885643,DB0037710008469_,4.520310481,1.022144053,female,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,palonosetron,DB00377
,374103,DB00019,10008531,41,18971,30,9499,0.130026353,0.684295336,0.416694331,1.135755177,0.255752063,DB0001910008531_,1.363546808,-0.379365677,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,374124,DB00019,10060800,56,18956,6,9523,1.99974900474526e-05,4.689203333,2.023187247,13.32335279,0.000199671,DB0001910060800_,8.518839321,1.545262703,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,pegfilgrastim,DB00019
,374128,DB00904,10060800,100,22969,29,14427,0.000126046,2.165841387,1.419339993,3.399153988,0.000972652,DB0090410060800_,6.935484155,0.772808917,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,ondansetron,DB00904
,374137,DB00009,10008479,53,1298,117,1434,3.35995154336749e-05,0.500570748,0.351645939,0.704819278,0.000313512,DB0000910008479_,8.067672967,-0.692006335,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,alteplase,DB00009
,374163,DB01234,10041232,32,31593,23,32865,0.180041638,1.447304767,0.820660917,2.590722029,0.32389418,DB0123410041232_,1.127338421,0.369703046,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dexamethasone,DB01234
,374164,DB00572,10041349,38,2864,19,2107,0.179906379,1.471258229,0.824668995,2.709980472,0.323715716,DB0057210041349_,1.127889567,0.386117973,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,atropine,DB00572
,374353,DB01060,10044565,57,8530,29,5052,0.576107197,1.164121111,0.730912253,1.891021087,0.725446856,DB0106010044565_,0.32096746,0.151966391,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,amoxicillin,DB01060
,374403,DB00669,10028810,70,6307,7,1090,0.195603679,1.728128958,0.793113108,4.46725218,0.343771242,DB0066910028810_,1.067778837,0.547039296,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,sumatriptan,DB00669
,374650,DB01234,10031252,32,31593,59,32829,0.008562189,0.563599732,0.354497065,0.88127643,0.031439149,DB0123410031252_,3.459701387,-0.573410975,NA,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,374746,DB01101,10009887,35,7554,17,3891,0.884604699,1.060475911,0.577552616,2.021324002,0.951939928,DB0110110009887_,0.049253347,0.05871778,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,capecitabine,DB01101
,374938,DB01217,10037844,98,2656,6,262,0.377164397,1.610982119,0.704351441,4.540627637,0.547072051,DB0121710037844_,0.603174766,0.476844005,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,anastrozole,DB01217
,375081,DB00530,10042128,40,1768,19,1249,0.181940037,1.487073553,0.836776747,2.732189709,0.326321473,DB0053010042128_,1.11987227,0.39681013,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,erlotinib,DB00530
,375120,DB00316,10060961,60,65414,14,36939,0.001560567,2.420102155,1.336320296,4.689750826,0.007941821,DB0031610060961_,4.835612663,0.883809752,NA,10060961,Appetite disorder,10027433,Metabolism and nutrition disorders,Metab,acetaminophen,DB00316
,375377,DB00404,10040844,68,19824,23,9839,0.119006203,1.467356044,0.902177403,2.469265959,0.239791342,DB0040410040844_,1.427986143,0.383462172,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,alprazolam,DB00404
,375378,DB00425,10040844,37,12658,17,7467,0.480921242,1.283900972,0.704505217,2.433303846,0.645627208,DB0042510040844_,0.437533019,0.249903078,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,zolpidem,DB00425
,375426,DB00331,10046274,10,24936,43,20709,1.15045763635249e-07,0.193165335,0.086492396,0.39048202,2.06181461669744e-06,DB0033110046274_,13.09192408,-1.644208798,male,10046274,Upper gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,375457,DB00399,10013971,31,6961,21,4977,0.88879501,1.055455525,0.586622355,1.935000565,0.953896257,DB0039910013971_,0.047200359,0.053972451,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,zoledronic acid,DB00399
,375474,DB00758,10017413,33,8267,56,10018,0.135410341,0.714114013,0.44939709,1.118497994,0.26327841,DB0075810017413_,1.334543214,-0.336712647,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,clopidogrel,DB00758
,375488,DB00758,10033557,46,8254,30,10044,0.00774635,1.865770005,1.151636514,3.064158929,0.029027414,DB0075810033557_,3.539514579,0.623673839,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,clopidogrel,DB00758
,375491,DB00377,10043554,38,1081,34,689,0.17584183,0.712510079,0.432059151,1.179139124,0.318451846,DB0037710043554_,1.144284005,-0.33896122,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,palonosetron,DB00377
,375617,DB00904,10011878,35,23034,35,14421,0.050069391,0.626105092,0.380296425,1.030659251,0.125137772,DB0090410011878_,2.078339974,-0.468237043,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,ondansetron,DB00904
,375736,DB00207,10039101,51,9029,21,5434,0.179041533,1.461571289,0.862530284,2.561115497,0.322700771,DB0020710039101_,1.131029792,0.379512082,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,azithromycin,DB00207
,375829,DB00207,10061818,48,9032,31,5424,0.815902019,0.929860637,0.57907104,1.513192245,0.901319012,DB0020710061818_,0.10389602,-0.072720557,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,azithromycin,DB00207
,375906,DB00230,10039674,65,19609,14,8637,0.013857155,2.044953337,1.135066943,3.948028776,0.046178804,DB0023010039674_,3.075234382,0.715374971,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,376134,DB00190,10033371,60,3237,52,4622,0.009028793,1.647389224,1.114084046,2.44304137,0.032806443,DB0019010033371_,3.417130335,0.499191746,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,376192,DB00482,10048010,43,8216,9,3062,0.119884624,1.780594801,0.854816055,4.15919315,0.241209993,DB0048210048010_,1.422087385,0.576947466,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,celecoxib,DB00482
,376340,DB01195,10006093,38,1201,27,717,0.516236592,0.840307799,0.494981735,1.44434004,0.675921593,DB0119510006093_,0.391678196,-0.173987027,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,flecainide,DB01195
,376443,DB00973,10041349,38,3813,22,2999,0.296368502,1.358473376,0.781304446,2.416948309,0.462248692,DB0097310041349_,0.771652239,0.306361552,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,ezetimibe,DB00973
,376475,DB01129,10064848,52,860,56,380,1.39158690185025e-05,0.410596991,0.270452734,0.622401156,0.000145237,DB0112910064848_,8.837145765,-0.890143102,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,rabeprazole,DB01129
,376593,DB00656,10036790,34,11979,19,6600,1,0.98593132,0.546158753,1.831284984,1,DB0065610036790_,0,-0.014168582,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,trazodone,DB00656
,376603,DB06589,10037844,36,1994,53,2600,0.591448397,0.88572164,0.560997474,1.384206254,0.737822975,DB0658910037844_,0.304051354,-0.121352554,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,pazopanib,DB06589
,376608,DB01068,10005425,41,13722,15,6825,0.393807133,1.359500618,0.736100528,2.646107104,0.563783352,DB0106810005425_,0.573085229,0.30711744,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,clonazepam,DB01068
,376645,DB00169,10034568,40,38651,19,18156,1,0.988930705,0.559322344,1.80833089,1,DB0016910034568_,0,-0.011131016,NA,10034568,Peripheral coldness,10047065,Vascular disorders,Vasc,cholecalciferol,DB00169
,376656,DB01098,10043071,32,8117,24,7185,0.592774818,1.180225577,0.672952057,2.096172276,0.738930385,DB0109810043071_,0.302551564,0.165705587,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,rosuvastatin,DB01098
,376726,DB00051,10061246,52,25679,10,11410,0.012533691,2.310482675,1.161031575,5.101378796,0.042633202,DB0005110061246_,3.155121945,0.837456453,NA,10061246,Intervertebral disc degeneration,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,376877,DB00688,10065553,39,6451,28,5350,0.623221366,1.155119828,0.691809022,1.951977102,0.763308961,DB0068810065553_,0.2700924,0.144204086,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,mycophenolate mofetil,DB00688
,377050,DB06637,10043417,50,6112,16,2003,1,1.024118274,0.571994129,1.931198646,1,DB0663710043417_,0,0.023832021,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,377116,DB04854,10011906,32,749,47,1439,0.27807061,1.30786997,0.800289981,2.113516981,0.441823489,DB0485410011906_,0.816844822,0.268399837,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,febuxostat,DB04854
,377176,DB00698,10011224,55,3093,7,422,1,1.071995738,0.482619976,2.808815144,1,DB0069810011224_,0,0.069522087,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nitrofurantoin,DB00698
,377220,DB09035,10012671,50,4676,67,6623,0.777777052,1.056977472,0.716343018,1.550728563,0.878852627,DB0903510012671_,0.129138055,0.055413393,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,nivolumab,DB09035
,377369,DB00635,10037868,41,33012,31,23763,0.904968115,0.952059815,0.582449509,1.570702261,0.957667115,DB0063510037868_,0.043255041,-0.049127415,NA,10037868,Rash maculo-papular,10040785,Skin and subcutaneous tissue disorders,Skin,prednisone,DB00635
,377379,DB00761,10040984,41,15266,15,8610,0.16490035,1.541569258,0.834840258,3.000096009,0.303987495,DB0076110040984_,1.190768713,0.432800896,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,potassium chloride,DB00761
,377583,DB08820,10001551,29,4372,31,3514,0.297862287,0.751929513,0.436320986,1.292441761,0.463752088,DB0882010001551_,0.768405162,-0.285112692,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,ivacaftor,DB08820
,377706,DB14513,10023232,60,7117,25,3539,0.489996208,1.193385135,0.735555921,1.989971614,0.653353133,DB1451310023232_,0.42563751,0.17679392,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium,DB14513
,377746,DB00482,10020937,86,8173,35,3036,0.680896744,0.912760203,0.607988648,1.396842717,0.807023985,DB0048210020937_,0.21440189,-0.091282081,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,celecoxib,DB00482
,377759,DB00973,10029331,38,3813,26,2995,0.615122369,1.147955617,0.677328853,1.973925479,0.756544533,DB0097310029331_,0.278993881,0.137982636,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,ezetimibe,DB00973
,377837,DB00230,10061148,44,19630,7,8644,0.00891946,2.767776779,1.236141376,7.286423566,0.032481019,DB0023010061148_,3.427099393,1.018044391,female,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,pregabalin,DB00230
,377838,DB00497,10061148,41,19226,24,16351,0.170458456,1.452855915,0.856858243,2.514761767,0.311479381,DB0049710061148_,1.166422135,0.373531216,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,oxycodone,DB00497
,377915,DB00115,10060820,49,18376,15,10457,0.036697932,1.858883428,1.02460805,3.570862857,0.098968431,DB0011510060820_,2.312954356,0.619976,NA,10060820,Joint injury,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,378031,DB08907,10013700,39,4214,17,3893,0.010191183,2.119094572,1.168824025,4.002205761,0.036102235,DB0890710013700_,3.321400491,0.750988909,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,canagliflozin,DB08907
,378139,DB00316,10005287,44,65430,27,36926,0.712877787,0.919698084,0.556897709,1.544820506,0.829389958,DB0031610005287_,0.187064838,-0.083709833,NA,10005287,Blood albumin decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,378211,DB00316,10006825,35,65439,19,36934,1,1.039692399,0.578593243,1.924207507,1,DB0031610006825_,0,0.0389249,NA,10006825,C-reactive protein increased,10022891,Investigations,Inv,acetaminophen,DB00316
,378356,DB01225,10020937,52,4992,30,4610,0.045287134,1.600611847,1.000257904,2.603752383,0.116139549,DB0122510020937_,2.152962804,0.47038596,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,enoxaparin,DB01225
,378397,DB00567,10022000,44,4475,14,2067,0.257450294,1.451619154,0.778656989,2.874838574,0.418366675,DB0056710022000_,0.871397018,0.372679591,NA,10022000,Influenza,10021881,Infections and infestations,Infec,cephalexin,DB00567
,378529,DB00695,10029883,40,28009,21,20507,0.243973496,1.394575151,0.802643017,2.490260387,0.402437611,DB0069510029883_,0.910215198,0.332589818,NA,10029883,Obesity,10027433,Metabolism and nutrition disorders,Metab,furosemide,DB00695
,378791,DB00567,10050584,57,4462,11,2070,0.005514706,2.403673079,1.24431467,5.095278859,0.022123634,DB0056710050584_,3.81110883,0.876998017,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,cephalexin,DB00567
,379139,DB00181,10076309,50,9806,21,5850,0.21844369,1.42038275,0.836713938,2.492279646,0.37166842,DB0018110076309_,0.989753166,0.350926378,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,379142,DB01225,10076309,50,4994,18,4622,0.000355732,2.570466809,1.471346967,4.689738194,0.002325399,DB0122510076309_,6.063863726,0.94408752,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,enoxaparin,DB01225
,379146,DB06285,10010264,48,8802,8,1098,0.396860138,0.748492597,0.349791748,1.836934599,0.566465856,DB0628510010264_,0.568338473,-0.289693966,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,379199,DB00540,10047895,41,2442,15,1076,0.661023454,1.204291664,0.649309199,2.352861942,0.793169926,DB0054010047895_,0.231717798,0.185891563,NA,10047895,Weight decreased,10022891,Investigations,Inv,nortriptyline,DB00540
,379235,DB08932,10023644,62,19381,13,6584,0.142434588,1.620086291,0.880901489,3.214016867,0.273227013,DB0893210023644_,1.297452279,0.482479414,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,macitentan,DB08932
,379269,DB09073,10012735,1408,18852,37,753,0.011908858,1.519928709,1.087000378,2.185396733,0.040920888,DB0907310012735_,3.19611464,0.418663432,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,palbociclib,DB09073
,379273,DB09073,10035664,338,19922,18,772,0.202881498,0.727680199,0.450378655,1.24955097,0.352426407,DB0907310035664_,1.042913453,-0.317893615,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,palbociclib,DB09073
,379309,DB00343,10013946,82,8654,21,5074,0.000432863,2.289310543,1.401666056,3.899005317,0.002737352,DB0034310013946_,5.90076412,0.8282507,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,379336,DB14500,10015150,68,7741,23,4050,0.076016317,1.546764548,0.949994487,2.605238867,0.171495057,DB1450010015150_,1.763200837,0.436165361,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,potassium,DB14500
,379453,DB00741,10007882,33,4061,29,3145,0.699998325,0.88127591,0.517551287,1.508038109,0.81975745,DB0074110007882_,0.198746775,-0.126384524,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,hydrocortisone,DB00741
,379510,DB06723,10011906,33,997,24,586,0.48591086,0.808292808,0.458392099,1.44434776,0.649960453,DB0672310011906_,0.430843759,-0.2128309,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,aluminum hydroxide,DB06723
,379546,DB00843,10061422,32,2162,47,2126,0.088720751,0.669578888,0.411723598,1.07643478,0.19312836,DB0084310061422_,1.644400234,-0.401106289,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,donepezil,DB00843
,379570,DB01098,10040829,41,8108,15,7194,0.00284636,2.424977098,1.312888185,4.720784577,0.01295413,DB0109810040829_,4.346340659,0.88582208,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,rosuvastatin,DB01098
,379581,DB01104,10054112,138,15325,76,7210,0.270392907,0.854297208,0.640118034,1.147395712,0.433093298,DB0110410054112_,0.836802105,-0.157476127,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,sertraline,DB01104
,379582,DB00186,10061224,38,16863,12,9996,0.057202872,1.877085336,0.959682298,3.947871087,0.138183761,DB0018610061224_,1.979170882,0.629720221,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,lorazepam,DB00186
,379670,DB00394,10040753,88,1551,19,775,0.000665392,2.313616965,1.385042575,4.054903955,0.0039303,DB0039410040753_,5.539039597,0.838812086,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,beclomethasone dipropionate,DB00394
,379671,DB00983,10040753,97,3404,17,1723,1.1785261289426e-05,2.887668847,1.706966582,5.176533176,0.000125364,DB0098310040753_,8.984285343,1.060449549,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,formoterol,DB00983
,379741,DB01136,10060800,41,9843,17,11098,0.000319137,2.719145856,1.509932731,5.107530474,0.002122061,DB0113610060800_,6.155367696,1.000317807,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,carvedilol,DB01136
,379770,DB00863,10022687,33,10640,17,5823,0.883447755,1.062356967,0.574428652,2.03541728,0.951268864,DB0086310022687_,0.04995854,0.060489993,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,379772,DB08931,10022687,55,6522,22,2424,0.796946988,0.929164727,0.556004486,1.603823138,0.890074285,DB0893110022687_,0.116450354,-0.07346924,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,379833,DB00338,10054107,45,33629,9,22263,0.000399282,3.310007628,1.597443239,7.70336505,0.002558853,DB0033810054107_,5.968196005,1.196950494,female,10054107,Nodule,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,379850,DB01261,10070863,24,3757,34,3269,0.084948748,0.614243627,0.347711821,1.069220722,0.186703276,DB0126110070863_,1.67823468,-0.487363642,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,sitagliptin,DB01261
,379880,DB00715,10001760,46,4797,8,2279,0.005148476,2.731449481,1.273835301,6.712279666,0.020937215,DB0071510001760_,3.866227086,1.004832414,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,paroxetine,DB00715
,379886,DB00175,10074903,52,8079,26,6080,0.107698071,1.505093092,0.921654644,2.514061899,0.222683772,DB0017510074903_,1.502002576,0.408854752,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,379967,DB14512,10044565,38,4806,21,2391,0.679784071,0.900260606,0.513758317,1.618481184,0.806323299,DB1451210044565_,0.215270501,-0.105070995,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,mometasone furoate,DB14512
,380013,DB00364,10000059,41,2709,17,1383,0.576129138,1.231159717,0.681261012,2.320332787,0.725457108,DB0036410000059_,0.32095333,0.207956584,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,sucralfate,DB00364
,380018,DB00437,10022004,20,6901,31,11515,0.774516899,1.076510015,0.581068776,1.951552379,0.87707399,DB0043710022004_,0.131163923,0.073724341,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,380070,DB08931,10061623,62,6515,15,2431,0.156247353,1.542310791,0.865016129,2.924972569,0.292393682,DB0893110061623_,1.229654157,0.433281805,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,380123,DB00193,10061520,37,19283,16,8686,1,1.041644679,0.56502892,2.006675519,1,DB0019310061520_,0,0.040800886,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,380126,DB01076,10061520,55,25692,33,25550,0.024564607,1.65742909,1.05701324,2.635550534,0.072540243,DB0107610061520_,2.623613799,0.505267661,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,380234,DB01234,10011831,20,31605,34,32854,0.101386641,0.611489467,0.333439126,1.09346538,0.212957316,DB0123410011831_,1.546663526,-0.491857549,NA,10011831,Cytomegalovirus infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,380236,DB01234,10014062,49,31576,32,32856,0.044890642,1.593299977,0.999835361,2.571475142,0.115364831,DB0123410014062_,2.159655727,0.465807323,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,dexamethasone,DB01234
,380292,DB00956,10005750,52,5762,22,3445,0.186119279,1.413126881,0.841602341,2.447944949,0.331607925,DB0095610005750_,1.103801958,0.345804895,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,hydrocodone,DB00956
,380374,DB00264,10061148,36,29571,24,24868,0.437110014,1.261431939,0.731916876,2.210721665,0.605628379,DB0026410061148_,0.501488717,0.232247536,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,380484,DB00722,10014062,41,25362,30,26002,0.191084851,1.401138222,0.853475163,2.324591264,0.337930788,DB0072210014062_,1.084914174,0.337284922,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,380571,DB01104,10033864,30,15433,30,7256,0.005057768,0.470167962,0.273618302,0.807942077,0.020648198,DB0110410033864_,3.880127239,-0.754665281,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,sertraline,DB01104
,380573,DB00425,10048010,55,12640,16,7468,0.013216127,2.030886611,1.145860836,3.800117078,0.044459706,DB0042510048010_,3.113171992,0.708472452,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,380575,DB01175,10048010,54,10670,22,4870,0.711208484,1.120291237,0.670057494,1.934172396,0.827814237,DB0117510048010_,0.188966502,0.113588685,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,escitalopram,DB01175
,380650,DB00213,10021027,37,18858,23,13398,0.694629319,1.142885365,0.661047586,2.015695284,0.816197212,DB0021310021027_,0.203099272,0.133556087,NA,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,pantoprazole,DB00213
,380792,DB01373,10016326,42,22678,9,7372,0.327950162,1.516950855,0.72741449,3.546130458,0.496467777,DB0137310016326_,0.700236698,0.416702304,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,380803,DB00451,10060961,46,47225,11,15408,0.441771566,1.364368822,0.695943355,2.921964577,0.609894929,DB0045110060961_,0.494468584,0.31069192,NA,10060961,Appetite disorder,10027433,Metabolism and nutrition disorders,Metab,levothyroxine,DB00451
,380853,DB13867,10064911,44,4506,10,2544,0.006557873,2.483882362,1.2289638,5.544732231,0.025421975,DB1386710064911_,3.672141324,0.909822805,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,381097,DB00559,10061494,40,9619,30,3276,0.001438495,0.454125895,0.275344015,0.756384622,0.007427726,DB0055910061494_,4.902535462,-0.789380818,NA,10061494,Rhinovirus infection,10021881,Infections and infestations,Infec,bosentan,DB00559
,381190,DB00722,10053156,38,25365,23,26009,0.053862214,1.694092753,0.983403113,2.979571117,0.132252993,DB0072210053156_,2.023038576,0.527147348,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,lisinopril,DB00722
,381192,DB00868,10000087,46,2938,15,1631,0.08009162,1.702248484,0.929805052,3.293225788,0.178543655,DB0086810000087_,1.722922144,0.531950015,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,benzonatate,DB00868
,381214,DB00514,10012735,103,2063,40,1496,0.000710729,1.866974003,1.275493045,2.778915832,0.004146378,DB0051410012735_,5.485520076,0.62431894,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dextromethorphan,DB00514
,381232,DB00567,10015090,41,4478,13,2068,0.302951268,1.456421297,0.763038815,2.969013553,0.469341001,DB0056710015090_,0.756425694,0.37598226,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cephalexin,DB00567
,381332,DB01137,10028735,38,7734,13,5580,0.021961524,2.108846202,1.097592768,4.318622918,0.066550457,DB0113710028735_,2.709794869,0.746140974,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,levofloxacin,DB01137
,381414,DB00695,10067482,76,27973,51,20477,0.653939401,1.090884311,0.754729267,1.588163164,0.787852518,DB0069510067482_,0.238444366,0.086988662,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,381416,DB01104,10067482,63,15400,26,7260,0.64920929,1.14229398,0.712192406,1.881410252,0.784122512,DB0110410067482_,0.243190005,0.133038504,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,381438,DB00682,10037153,41,19418,34,16330,1,1.014114211,0.627589641,1.648376813,1,DB0068210037153_,0,0.014015533,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,warfarin,DB00682
,381457,DB06186,10035598,43,2166,47,3599,0.049193251,1.520006203,0.977716788,2.357898944,0.123464586,DB0618610035598_,2.091800918,0.418714415,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ipilimumab,DB06186
,381464,DB00761,10014418,38,15269,17,8608,0.483714985,1.260183631,0.693765565,2.382465491,0.647955274,DB0076110014418_,0.433933607,0.231257449,NA,10014418,Electrolyte imbalance,10027433,Metabolism and nutrition disorders,Metab,potassium chloride,DB00761
,381503,DB01118,10015090,22,3041,40,4669,0.602343552,0.844485276,0.476989175,1.458744116,0.746347516,DB0111810015090_,0.292563949,-0.169027978,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,381627,DB00169,10028116,37,38654,13,18162,0.448584099,1.337337504,0.694545341,2.742487369,0.616258228,DB0016910028116_,0.484089203,0.2906807,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,381744,DB00230,10003986,46,19628,15,8636,0.403503386,1.349217349,0.739280837,2.603348636,0.573224511,DB0023010003986_,0.556477822,0.299524683,NA,10003986,Back injury,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,381780,DB00476,10061599,39,17218,12,6165,0.751264369,1.163669438,0.596488099,2.442857526,0.859540781,DB0047610061599_,0.151357008,0.151578321,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,381896,DB08895,10047924,67,28047,10,6636,0.193068619,1.585208755,0.810220541,3.457971801,0.340476931,DB0889510047924_,1.077407907,0.460716105,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,381927,DB00455,10013911,49,9352,25,5093,0.902999113,1.067395692,0.645745917,1.805880756,0.957326661,DB0045510013911_,0.043610607,0.065221749,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,loratadine,DB00455
,381934,DB00275,10028334,41,2019,16,1221,0.167310337,1.549490352,0.846524866,2.971429716,0.307279987,DB0027510028334_,1.179995936,0.437926072,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,olmesartan,DB00275
,382045,DB06605,10007598,44,14029,20,13013,0.008108784,2.040613859,1.176973086,3.656803049,0.030117195,DB0660510007598_,3.502659019,0.713250674,NA,10007598,Cardiac pacemaker insertion,10042613,Surgical and medical procedures,Surg,apixaban,DB06605
,382046,DB06605,10033318,160,13913,70,12963,5.94188458171998e-08,2.129493059,1.596644883,2.865171453,1.12807826818714e-06,DB0660510033318_,13.69499502,0.755883951,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,apixaban,DB06605
,382083,DB00121,10048959,101,4122,7,461,0.257501123,1.613537751,0.748855987,4.140743478,0.418397541,DB0012110048959_,0.871323244,0.478429129,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,382106,DB00333,10024264,22,3049,38,3114,0.051953276,0.591341814,0.332287419,1.028351518,0.128726196,DB0033310024264_,2.050067644,-0.525361063,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,methadone,DB00333
,382145,DB01065,10017577,82,4249,43,3008,0.119831102,1.34995421,0.919359507,2.006793515,0.241130996,DB0106510017577_,1.422414943,0.300070673,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,382146,DB06262,10017577,71,3729,78,4236,0.868568941,1.034023452,0.736660169,1.449336702,0.941418276,DB0626210017577_,0.060367737,0.033457456,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,382150,DB06262,10019063,40,3760,78,4236,0.005122875,0.577781247,0.383445924,0.858817128,0.020862152,DB0626210019063_,3.869818693,-0.548559948,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,droxidopa,DB06262
,382198,DB00230,10048049,44,19630,9,8642,0.035688131,2.152257359,1.036368177,5.016715518,0.096857257,DB0023010048049_,2.334516964,0.766517226,NA,10048049,Wrist fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,382221,DB00005,10069853,122,127960,26,42393,0.045179359,1.554507725,1.011384592,2.474745906,0.115931024,DB0000510069853_,2.154759887,0.44115892,NA,10069853,Device difficult to use,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,382232,DB00374,10014011,48,17668,6,5718,0.025019907,2.589122326,1.105560111,7.40796325,0.073503405,DB0037410014011_,2.610423548,0.951318948,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,382233,DB00820,10014011,58,11857,9,5807,0.000379363,3.156024569,1.551591247,7.251406632,0.002455195,DB0082010014011_,6.009549159,1.149313188,female,10014011,Ear infection,10021881,Infections and infestations,Infec,tadalafil,DB00820
,382234,DB06403,10014011,66,21405,6,6655,0.001216082,3.419975696,1.489306694,9.656622978,0.00646928,DB0640310014011_,5.040690536,1.229633445,female,10014011,Ear infection,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,382251,DB00567,10064848,58,4461,32,2049,0.42453807,0.832546933,0.529858657,1.329334599,0.593350893,DB0056710064848_,0.52196933,-0.183265683,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,cephalexin,DB00567
,382287,DB00273,10008531,56,8425,11,2182,0.451871349,1.318463143,0.681993108,2.795700183,0.619465649,DB0027310008531_,0.478898029,0.276466772,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,382390,DB00153,10070608,69,7354,34,3405,0.750620061,0.939651231,0.613199639,1.46459583,0.859042051,DB0015310070608_,0.151937405,-0.062246503,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,ergocalciferol,DB00153
,382391,DB00455,10070608,63,9338,51,5067,0.038452491,0.670288909,0.45525189,0.99113927,0.102543714,DB0045510070608_,2.277466089,-0.400046452,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,loratadine,DB00455
,382397,DB01306,10070608,36,4172,28,3838,0.532091047,1.182757755,0.70034668,2.016459212,0.688976623,DB0130610070608_,0.372547938,0.167848792,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,insulin aspart,DB01306
,382434,DB00065,10033557,44,9420,20,4937,0.692747062,1.1529911,0.66456443,2.067403487,0.814932712,DB0006510033557_,0.204649731,0.142359522,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,infliximab,DB00065
,382457,DB08932,10022086,48,19395,10,6587,0.175451796,1.630102733,0.813781276,3.615953197,0.317942121,DB0893210022086_,1.145885921,0.488643039,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,382474,DB01306,10005750,30,4178,24,3842,0.682501725,1.149453078,0.648383696,2.058348568,0.80796081,DB0130610005750_,0.213241724,0.139286245,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,insulin aspart,DB01306
,382590,DB00343,10022004,41,8695,17,5078,0.27566812,1.40847052,0.781736462,2.647141662,0.438921558,DB0034310022004_,0.823434565,0.342504378,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,382681,DB01238,10014387,41,5209,22,3480,0.441003433,1.245006472,0.723039167,2.198845668,0.609222901,DB0123810014387_,0.495571067,0.219140728,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,aripiprazole,DB01238
,382720,DB00695,10013578,41,28008,40,20488,0.215773903,0.749806066,0.472859789,1.189733087,0.368334657,DB0069510013578_,0.99876336,-0.287940685,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,382742,DB01592,10069339,52,6224,54,3013,0.000105666,0.466196687,0.31149728,0.697154499,0.000836564,DB0159210069339_,7.086207254,-0.76314766,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,iron,DB01592
,382797,DB00421,10007556,44,8859,24,5228,0.80243503,1.081916561,0.642842214,1.862500182,0.893152549,DB0042110007556_,0.112997885,0.078734062,NA,10007556,Cardiac failure acute,10007541,Cardiac disorders,Card,spironolactone,DB00421
,382909,DB08907,10049414,41,4212,45,3865,0.448066276,0.836070412,0.532722515,1.308939859,0.615829019,DB0890710049414_,0.484785921,-0.179042444,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,canagliflozin,DB08907
,382971,DB01276,10074903,30,1987,27,1484,0.502112227,0.829886546,0.47455698,1.457673213,0.663444193,DB0127610074903_,0.410310539,-0.18646628,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,exenatide,DB01276
,382977,DB05676,10002368,43,47086,44,25285,0.003214563,0.524778646,0.336492397,0.818018948,0.014309026,DB0567610002368_,4.246864742,-0.644778732,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,383040,DB05676,10017533,61,47068,25,25304,0.30834667,1.311773812,0.811027171,2.181512804,0.475638905,DB0567610017533_,0.743096316,0.271380276,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,apremilast,DB05676
,383056,DB05676,10013786,174,46955,90,25239,0.796182024,1.03919625,0.800753936,1.356390077,0.889629506,DB0567610013786_,0.116950188,0.038447577,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,383087,DB00557,10074903,56,5931,17,3050,0.062110976,1.693900907,0.96794695,3.115381812,0.147389541,DB0055710074903_,1.914676262,0.527034098,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxyzine,DB00557
,383110,DB00443,10012378,36,2110,14,1176,0.298835528,1.433029229,0.750601938,2.888538465,0.464805301,DB0044310012378_,0.766136669,0.359790546,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,betamethasone,DB00443
,383133,DB00019,10020772,33,18979,27,9502,0.073693378,0.611911309,0.35658047,1.058650778,0.167664715,DB0001910020772_,1.785789039,-0.491167927,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,pegfilgrastim,DB00019
,383138,DB00019,10061623,36,18976,14,9515,0.45693837,1.289409148,0.678259123,2.589165557,0.624287256,DB0001910061623_,0.47114467,0.254184088,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,383206,DB01062,10010144,55,4431,75,1670,1.30587883144799e-12,0.276453909,0.190669467,0.398719134,5.78349201088636e-11,DB0106210010144_,23.57342837,-1.285711165,male,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,oxybutynin,DB01062
,383247,DB00047,10076308,35,9250,31,8487,0.902461729,1.035907735,0.619828971,1.738889923,0.957195726,DB0004710076308_,0.043747388,0.035278081,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,383248,DB00281,10076308,91,11367,43,5628,0.854049004,1.047803443,0.720256035,1.545314251,0.928917223,DB0028110076308_,0.073735648,0.046696014,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lidocaine,DB00281
,383249,DB00425,10076308,75,12620,33,7451,0.163643997,1.341826683,0.878912425,2.088944053,0.302307514,DB0042510076308_,1.196310521,0.294031882,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,383252,DB00697,10076308,57,6039,25,1781,0.111767615,0.672446999,0.411980646,1.126758418,0.22872138,DB0069710076308_,1.475250697,-0.396831982,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tizanidine,DB00697
,383254,DB01076,10076308,104,25643,106,25477,0.890075829,0.974776433,0.736083916,1.290605643,0.954444894,DB0107610076308_,0.046625371,-0.025547134,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,383256,DB01175,10076308,55,10669,29,4863,0.5556444,0.864479057,0.540972238,1.407936719,0.709037699,DB0117510076308_,0.343846581,-0.145628199,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,383265,DB05676,10011781,66,47063,12,25317,0.000185452,2.958619488,1.58519805,6.015315901,0.001353307,DB0567610011781_,6.605203869,1.08472277,female,10011781,Cystitis,10021881,Infections and infestations,Infec,apremilast,DB05676
,383295,DB00688,10010305,45,6445,39,5339,0.91250795,0.955821448,0.607585785,1.509587068,0.960726604,DB0068810010305_,0.040065401,-0.045184153,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,mycophenolate mofetil,DB00688
,383360,DB01069,10007515,59,6641,22,2373,0.899193492,0.958284568,0.576944866,1.646283892,0.956490275,DB0106910007515_,0.044484657,-0.042610502,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,promethazine,DB01069
,383375,DB00916,10007515,40,5283,42,2389,0.000176407,0.430718863,0.271452201,0.682511755,0.001297023,DB0091610007515_,6.647684009,-0.842299691,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,metronidazole,DB00916
,383417,DB08907,10000087,33,4220,18,3892,0.090676704,1.690724479,0.923008037,3.194840111,0.196280752,DB0890710000087_,1.628209236,0.525157123,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,canagliflozin,DB08907
,383462,DB00924,10038669,91,10071,35,4216,0.76853013,1.088424511,0.728215436,1.659541642,0.8730768,DB0092410038669_,0.135731755,0.084731248,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclobenzaprine,DB00924
,383480,DB00381,10043089,37,29323,19,22868,0.140955111,1.518671413,0.850979448,2.796478263,0.271220314,DB0038110043089_,1.30482382,0.417835882,NA,10043089,Tachypnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,383494,DB01156,10022081,48,13574,23,6305,0.898780968,0.969402308,0.577614287,1.671359431,0.95647837,DB0115610022081_,0.044497104,-0.031075575,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,383530,DB00947,10076309,75,3097,10,58,7.59449579869007e-06,0.140641129,0.067870711,0.320853005,8.52718163471031e-05,DB0094710076309_,9.369666564,-1.961543821,male,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fulvestrant,DB00947
,383547,DB00334,10007515,62,2787,59,2753,0.854649872,1.03803114,0.711935768,1.514780092,0.929436156,DB0033410007515_,0.07317716,0.037325785,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,olanzapine,DB00334
,383549,DB00334,10038669,37,2812,32,2780,0.628860358,1.14306439,0.690627591,1.901267831,0.768014613,DB0033410038669_,0.263946519,0.133712718,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,olanzapine,DB00334
,383608,DB00734,10047895,33,4017,30,4872,0.256241082,1.334076756,0.787280246,2.26875637,0.417059156,DB0073410047895_,0.874527206,0.288239484,NA,10047895,Weight decreased,10022891,Investigations,Inv,risperidone,DB00734
,383666,DB01224,10021143,51,8057,28,5889,0.253699792,1.331286017,0.822655143,2.195477432,0.414218215,DB0122410021143_,0.881362356,0.286145405,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,quetiapine,DB01224
,383726,DB11750,10047700,73,2427,25,1488,0.011249773,1.79001857,1.116979551,2.956951789,0.03911638,DB1175010047700_,3.241213964,0.582225994,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,clobetasol,DB11750
,383727,DB00586,10068319,57,7052,18,2787,0.442912585,1.251445075,0.724302653,2.26372836,0.610982041,DB0058610068319_,0.492687714,0.224298944,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diclofenac,DB00586
,383897,DB00338,10037437,40,33634,42,22230,0.041622708,0.629489111,0.397718725,0.994886091,0.108969411,DB0033810037437_,2.216688067,-0.462846723,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,omeprazole,DB00338
,384033,DB00373,10022806,32,1800,29,1258,0.35816195,0.771261953,0.449360063,1.328783495,0.527878861,DB0037310022806_,0.638888452,-0.259727206,NA,10022806,Intraocular pressure increased,10022891,Investigations,Inv,timolol,DB00373
,384120,DB00788,10076309,99,9257,44,5017,0.291749505,1.219374578,0.845158027,1.784368254,0.457206032,DB0078810076309_,0.782621154,0.198338087,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,384182,DB01241,10011906,27,916,37,1034,0.52482921,0.823813748,0.478309946,1.402407492,0.682961323,DB0124110011906_,0.381317048,-0.193810809,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,gemfibrozil,DB01241
,384353,DB00338,10049088,57,33617,7,22265,5.21363493616847e-07,5.392882576,2.454430438,14.02197434,8.04227666063311e-06,DB0033810049088_,11.73079835,1.685080043,female,10049088,Osteopenia,10028395,Musculoskeletal and connective tissue disorders,Musc,omeprazole,DB00338
,384367,DB00186,10061920,53,16848,46,9962,0.060812824,0.681300104,0.449879556,1.035012804,0.14491977,DB0018610061920_,1.931574997,-0.383752388,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,384446,DB11065,10022000,55,3131,59,2629,0.217207113,0.782778197,0.530034499,1.154470949,0.370144183,DB1106510022000_,0.993862665,-0.244905896,NA,10022000,Influenza,10021881,Infections and infestations,Infec,pancrelipase amylase,DB11065
,384459,DB00169,10061603,32,38659,18,18157,0.545885324,0.834987986,0.454592152,1.580389712,0.700597922,DB0016910061603_,0.355821134,-0.180337943,NA,10061603,Respiratory syncytial virus infection,10021881,Infections and infestations,Infec,cholecalciferol,DB00169
,384469,DB00341,10070608,101,11304,68,5000,0.009213362,0.656995108,0.477455619,0.90884161,0.03334571,DB0034110070608_,3.400826156,-0.420078706,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,cetirizine,DB00341
,384471,DB00471,10070608,129,14060,92,5373,1.00906851881357e-05,0.535884669,0.406152375,0.709372704,0.000109465,DB0047110070608_,9.119905826,-0.623836312,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,montelukast,DB00471
,384472,DB00635,10070608,80,32973,55,23739,0.861424252,1.047209412,0.733379371,1.504865292,0.935178278,DB0063510070608_,0.067018097,0.046128924,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,prednisone,DB00635
,384529,DB00230,10016326,61,19613,14,8637,0.023937528,1.918721764,1.060264328,3.716719661,0.071091795,DB0023010016326_,2.643783352,0.651659216,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,384559,DB10631,10013709,43,1253,7,204,1,1.000094796,0.438050558,2.671488538,1,DB1063110013709_,0,9.47912224038604e-05,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cranberry,DB10631
,384583,DB08932,10061394,59,19384,10,6587,0.037594766,2.004983128,1.016391876,4.398832543,0.100772837,DB0893210061394_,2.294886436,0.695635646,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,384588,DB00763,10016256,40,730,14,287,0.876590001,1.123164823,0.587505331,2.270513305,0.947301106,DB0076310016256_,0.054138278,0.116150435,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,methimazole,DB00763
,384599,DB00175,10076308,44,8087,27,6079,0.471158185,1.224975256,0.74091308,2.059803149,0.637417926,DB0017510076308_,0.450329754,0.202920645,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,384600,DB00181,10076308,71,9785,38,5833,0.620702591,1.113806791,0.739858744,1.700268237,0.761218215,DB0018110076308_,0.272835214,0.107783689,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,384618,DB13867,10010305,40,4510,31,2523,0.173908664,0.721896248,0.439153027,1.196728003,0.316039079,DB1386710010305_,1.151889406,-0.325873852,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,fluticasone,DB13867
,384748,DB00480,10014062,61,67367,67,67595,0.658610985,0.913544829,0.634912788,1.312202104,0.79153192,DB0048010014062_,0.233785072,-0.09042283,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,384749,DB08889,10028334,46,3119,59,3826,0.843909757,0.956388868,0.634007634,1.434968671,0.921022521,DB0888910028334_,0.082270791,-0.044590683,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,carfilzomib,DB08889
,384757,DB08889,10043607,34,3131,44,3841,0.908968932,0.947950612,0.586036262,1.52153037,0.95913476,DB0888910043607_,0.041723693,-0.053452876,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,carfilzomib,DB08889
,384766,DB00490,10061428,63,4007,25,1551,0.905010458,0.975426514,0.602320517,1.624550273,0.957667115,DB0049010061428_,0.043255041,-0.024880453,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,buspirone,DB00490
,384796,DB01373,10048865,74,22646,20,7361,0.548366109,1.202660011,0.725280248,2.082899124,0.702803802,DB0137310048865_,0.352677513,0.184535779,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,calcium,DB01373
,384808,DB00480,10067484,50,67378,63,67599,0.258743402,0.796257021,0.538003249,1.1729742,0.419832114,DB0048010067484_,0.867900376,-0.227833255,NA,10067484,Adverse reaction,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,384872,DB00787,10028164,76,16924,38,17210,0.00032315,2.033745319,1.359572068,3.088255263,0.002143863,DB0078710028164_,6.145145892,0.709879078,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,acyclovir,DB00787
,384889,DB09027,10047899,52,5127,40,7112,0.005618517,1.80318629,1.16917599,2.799445028,0.022464668,DB0902710047899_,3.795811497,0.589555261,NA,10047899,Weight increased,10022891,Investigations,Inv,ledipasvir,DB09027
,384890,DB00115,10046735,175,18250,52,10420,2.0750752832744e-05,1.921455178,1.401131687,2.674484498,0.000206252,DB0011510046735_,8.486411608,0.653082804,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,cyanocobalamin,DB00115
,384924,DB01234,10047482,35,31590,31,32857,0.53975258,1.174310712,0.703138012,1.969795971,0.695494708,DB0123410047482_,0.363131876,0.160681347,NA,10047482,Viral upper respiratory tract infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,384966,DB00480,10014011,101,67327,51,67611,4.39276326508561e-05,1.988724557,1.406372058,2.842859753,0.000395966,DB0048010014011_,7.83418137,0.687493507,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,384982,DB00073,10003658,39,7367,103,6304,2.77276207143568e-10,0.32403088,0.217833699,0.473449907,8.45499432107737e-09,DB0007310003658_,18.58850853,-1.126916458,male,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,rituximab,DB00073
,384999,DB09153,10035742,25,7774,30,5669,0.074915873,0.607724087,0.34228958,1.070268113,0.169711603,DB0915310035742_,1.773654737,-0.498034305,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,385005,DB00868,10040047,34,2950,34,1612,0.014956085,0.546495246,0.328230307,0.910013602,0.049201589,DB0086810040047_,3.011829357,-0.60422967,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,benzonatate,DB00868
,385103,DB00480,10030995,43,67385,19,67643,0.002185988,2.271944134,1.295709422,4.128468746,0.010463211,DB0048010030995_,4.559889916,0.820635912,NA,10030995,Oral mucosal blistering,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,385177,DB00480,10020765,83,67345,87,67575,0.818038946,0.957268846,0.699869917,1.308593296,0.902863836,DB0048010020765_,0.102183527,-0.043671002,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,385178,DB00480,10022998,55,67373,85,67577,0.013928041,0.649023681,0.453635333,0.921953469,0.046373877,DB0048010022998_,3.071018983,-0.432286074,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,385204,DB00433,10017944,34,7622,23,5997,0.595982337,1.163075498,0.664623698,2.070303633,0.741456274,DB0043310017944_,0.299139088,0.151067788,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,385206,DB00316,10041541,47,65427,46,36907,0.009202179,0.576390747,0.375489901,0.885155449,0.03331441,DB0031610041541_,3.401765257,-0.550969468,NA,10041541,Spinal compression fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,385237,DB00480,10075192,31,67397,44,67618,0.165358109,0.706860572,0.431485815,1.145130442,0.304611733,DB0048010075192_,1.188717319,-0.346921844,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,lenalidomide,DB00480
,385244,DB00404,10003983,36,19856,14,9848,0.54779563,1.275297664,0.670900658,2.561068322,0.702363754,DB0040410003983_,0.353303841,0.243179614,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,alprazolam,DB00404
,385289,DB00264,10012671,35,29572,29,24863,1,1.014712959,0.60235306,1.721520361,1,DB0026410012671_,0,0.014605773,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,metoprolol,DB00264
,385294,DB01261,10012671,26,3755,48,3255,0.002111718,0.46958644,0.278981082,0.774177223,0.010172026,DB0126110012671_,4.588113845,-0.755902886,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,sitagliptin,DB01261
,385430,DB00190,10038743,20,3277,44,4630,0.125547807,0.642252028,0.357890288,1.115285165,0.249416077,DB0019010038743_,1.388632786,-0.442774486,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,385474,DB00635,10042727,56,32997,22,23772,0.015522212,1.83379303,1.10154371,3.15529587,0.050629937,DB0063510042727_,2.983212241,0.606386516,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,prednisone,DB00635
,385590,DB01098,10065154,93,8056,58,7151,0.040203032,1.423283089,1.01280351,2.014396778,0.106073519,DB0109810065154_,2.243622849,0.352966237,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,rosuvastatin,DB01098
,385591,DB01175,10065154,73,10651,21,4871,0.073560779,1.589716103,0.96601783,2.723437373,0.167457244,DB0117510065154_,1.787027222,0.463555449,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,escitalopram,DB01175
,385676,DB00697,10076309,42,6054,10,1796,0.621198267,1.245948215,0.613606338,2.790658065,0.761528748,DB0069710076309_,0.272427355,0.219896858,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tizanidine,DB00697
,385677,DB00727,10039906,44,3799,37,4136,0.264797807,1.294632302,0.815107823,2.066540456,0.426757033,DB0072710039906_,0.851540437,0.258226718,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,nitroglycerin,DB00727
,385724,DB00313,10048294,12,1227,54,1463,7.06341276558353e-06,0.265080981,0.128452618,0.50455502,8.00438907278996e-05,DB0031310048294_,9.43293544,-1.32771991,male,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,valproic acid,DB00313
,385735,DB06228,10064373,27,15885,42,16034,0.09113105,0.648899213,0.384520785,1.077951504,0.197061384,DB0622810064373_,1.624240005,-0.432477871,NA,10064373,Labelled drug-drug interaction medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,385753,DB09029,10008190,40,11304,41,7229,0.039399342,0.623947724,0.392934314,0.99001025,0.104438454,DB0902910008190_,2.259157341,-0.471688691,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,secukinumab,DB09029
,385761,DB09033,10067482,280,2344,90,1579,9.05725455808188e-10,2.095398068,1.631838148,2.711011191,2.53805901982071e-08,DB0903310067482_,17.48928112,0.739743544,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,vedolizumab,DB09033
,385809,DB00787,10013990,20,16980,33,17215,0.098577417,0.614460419,0.333975778,1.103525819,0.208748569,DB0078710013990_,1.56662477,-0.487010764,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,acyclovir,DB00787
,385832,DB00987,10037377,15,2089,39,2889,0.037568812,0.531971795,0.271676541,0.990103085,0.100718673,DB0098710037377_,2.295424062,-0.631164807,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cytarabine,DB00987
,385974,DB06724,10020100,55,7874,17,3902,0.101940219,1.603207598,0.915181368,2.950670469,0.213867055,DB0672410020100_,1.542400697,0.472006371,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium carbonate,DB06724
,386011,DB01234,10035737,23,31602,30,32858,0.492334425,0.797141554,0.442088809,1.419644597,0.655224443,DB0123410035737_,0.422777441,-0.226723007,NA,10035737,Pneumonia viral,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,386063,DB00268,10028810,46,2929,15,1530,0.134533061,1.601758193,0.874789419,3.099266126,0.262008781,DB0026810028810_,1.339377259,0.471101896,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ropinirole,DB00268
,386092,DB00915,10010774,41,1414,28,1023,0.901713979,1.059367119,0.63469259,1.791539007,0.957082614,DB0091510010774_,0.043865565,0.057671672,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,amantadine,DB00915
,386144,DB00343,10054236,41,8695,18,5077,0.345928403,1.329965299,0.74623162,2.462220492,0.515351232,DB0034310054236_,0.662906608,0.285152851,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,diltiazem,DB00343
,386194,DB06637,10013700,44,6118,11,2008,0.530196032,1.312792809,0.665584752,2.823951679,0.687291153,DB0663710013700_,0.374997273,0.272156783,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,dalfampridine,DB06637
,386217,DB00758,10011781,40,8260,16,10058,0.000119606,3.044012727,1.665648749,5.827039459,0.000929031,DB0075810011781_,6.981368515,1.113176621,female,10011781,Cystitis,10021881,Infections and infestations,Infec,clopidogrel,DB00758
,386250,DB05676,10021097,48,47081,25,25304,1,1.031917681,0.6235978,1.746996865,1,DB0567610021097_,0,0.031418898,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,apremilast,DB05676
,386257,DB00864,10040753,20,6849,31,8361,0.481393564,0.787601397,0.425039561,1.427987716,0.646045387,DB0086410040753_,0.436885519,-0.238763159,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,386430,DB00190,10043417,23,3274,49,4625,0.118081206,0.663111654,0.384767211,1.111915101,0.238311156,DB0019010043417_,1.434178082,-0.410811896,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,386494,DB00843,10048959,38,2156,46,2127,0.379223065,0.815015092,0.51376154,1.286165091,0.549239787,DB0084310048959_,0.599220162,-0.204548648,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,donepezil,DB00843
,386530,DB11750,10048959,34,2466,19,1494,0.886776943,1.084123415,0.598565192,2.019752354,0.95296028,DB1175010048959_,0.048182056,0.080771748,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,clobetasol,DB11750
,386568,DB00115,10039203,59,18366,18,10454,0.017672138,1.865686108,1.08448594,3.363079596,0.056073413,DB0011510039203_,2.881093495,0.623628872,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,386589,DB01377,10020751,39,3757,12,2658,0.009796994,2.299024658,1.176633489,4.832029657,0.03500496,DB0137710020751_,3.352265503,0.832484971,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,magnesium oxide,DB01377
,386601,DB00924,10017413,37,10125,14,4237,0.877954345,1.105944471,0.583274781,2.217039356,0.948285522,DB0092410017413_,0.053099639,0.100699695,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,cyclobenzaprine,DB00924
,386612,DB00211,10069339,27,1409,44,1587,0.149124061,0.691241188,0.409255172,1.148215601,0.282777905,DB0021110069339_,1.263093476,-0.369266474,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,midodrine,DB00211
,386636,DB09027,10002034,34,5145,47,7105,1,0.998986907,0.62210612,1.589092156,1,DB0902710002034_,0,-0.001013606,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ledipasvir,DB09027
,386639,DB09027,10019641,21,5158,39,7113,0.296161644,0.742568781,0.414486158,1.295463346,0.462022008,DB0902710019641_,0.772142752,-0.297639778,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,ledipasvir,DB09027
,386713,DB01275,10020993,30,3949,31,3318,0.440777891,0.813135157,0.47441472,1.391917457,0.609092179,DB0127510020993_,0.495785662,-0.206857938,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,hydralazine,DB01275
,386735,DB00564,10007617,41,2563,30,1433,0.264385467,0.764188933,0.463376178,1.27340968,0.426315687,DB0056410007617_,0.852575158,-0.268940226,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,carbamazepine,DB00564
,386880,DB00215,10065154,42,11061,13,5263,0.19485984,1.537214313,0.808623014,3.12398328,0.342848762,DB0021510065154_,1.070465856,0.42997189,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,citalopram,DB00215
,386885,DB00425,10065154,74,12621,32,7452,0.1581759,1.365382589,0.889548408,2.138948453,0.295015507,DB0042510065154_,1.220727359,0.311434675,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,zolpidem,DB00425
,386886,DB00697,10065154,57,6039,10,1796,0.143566125,1.695036749,0.855707443,3.730932288,0.274896054,DB0069710065154_,1.291362238,0.527704421,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,tizanidine,DB00697
,386951,DB00341,10019303,62,11343,26,5042,0.907874395,1.059964972,0.659677997,1.748321943,0.958771936,DB0034110019303_,0.042102046,0.058235862,NA,10019303,Heart rate increased,10022891,Investigations,Inv,cetirizine,DB00341
,386967,DB01373,10040979,51,22669,17,7364,0.888513234,0.974546341,0.553161504,1.801144516,0.953826126,DB0137310040979_,0.047273882,-0.025783207,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,386998,DB06637,10000087,52,6110,12,2007,0.31014421,1.423320942,0.747925852,2.935714397,0.477571211,DB0663710000087_,0.739041998,0.352992833,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,dalfampridine,DB06637
,387023,DB08910,10057668,34,16710,37,17451,0.905730538,0.959658974,0.58402314,1.572531537,0.957861963,DB0891010057668_,0.0430516,-0.041177293,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,pomalidomide,DB08910
,387044,DB01261,10010144,28,3753,44,3259,0.01699914,0.552652622,0.330532518,0.910077809,0.054387729,DB0126110010144_,2.911616715,-0.593025644,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,sitagliptin,DB01261
,387051,DB00996,10048865,74,38879,52,22373,0.267997856,0.818925573,0.566450783,1.191500809,0.430411122,DB0099610048865_,0.843014428,-0.199762075,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,gabapentin,DB00996
,387070,DB01104,10001540,36,15427,14,7272,0.649478938,1.212093358,0.637490818,2.434358965,0.784287431,DB0110410001540_,0.242979705,0.192348913,NA,10001540,Akathisia,10029205,Nervous system disorders,Nerv,sertraline,DB01104
,387102,DB00656,10007882,48,11965,24,6595,0.805276035,1.102387579,0.661402398,1.883395598,0.894590507,DB0065610007882_,0.1113892,0.097478354,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,trazodone,DB00656
,387160,DB00019,10017412,55,18957,19,9510,0.175596668,1.45216065,0.847877034,2.592665042,0.318098159,DB0001910017412_,1.145395268,0.373052551,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,pegfilgrastim,DB00019
,387162,DB00019,10023547,41,18971,19,9510,0.891164805,1.081729327,0.613383245,1.974442866,0.954816394,DB0001910023547_,0.046236214,0.07856099,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,pegfilgrastim,DB00019
,387218,DB06724,10005557,47,7882,23,3896,1,1.010075329,0.600183664,1.745624854,1,DB0672410005557_,0,0.010024911,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,calcium carbonate,DB06724
,387255,DB00169,10048010,62,38629,18,18157,0.072449597,1.618998421,0.945024686,2.909088191,0.165565785,DB0016910048010_,1.798386671,0.4818077,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,387310,DB11065,10002855,38,3148,24,2664,0.305660884,1.339830547,0.780862764,2.34140815,0.472423566,DB1106510002855_,0.749879311,0.292543149,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,pancrelipase amylase,DB11065
,387313,DB11065,10003988,50,3136,29,2659,0.112081349,1.461792933,0.904298315,2.4030808,0.229191027,DB1106510003988_,1.473199444,0.379663719,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,pancrelipase amylase,DB11065
,387499,DB01005,10051608,46,1049,22,845,0.047299852,1.683855697,0.983502938,2.964179003,0.120030567,DB0100510051608_,2.120008843,0.521086222,NA,10051608,Platelet count increased,10022891,Investigations,Inv,hydroxyurea,DB01005
,387629,DB09027,10010305,34,5145,57,7095,0.39512511,0.822579994,0.520670818,1.281849624,0.564955722,DB0902710010305_,0.571007919,-0.195309544,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ledipasvir,DB09027
,387632,DB09027,10035664,32,5147,31,7121,0.161213603,1.428088323,0.842653522,2.423383681,0.299120991,DB0902710035664_,1.206907135,0.356336713,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ledipasvir,DB09027
,387634,DB00193,10073317,36,19284,16,8686,1,1.013461649,0.547909236,1.957149474,1,DB0019310073317_,0,0.013371846,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,387653,DB00213,10054889,31,18864,30,13391,0.242857673,0.733550798,0.429287112,1.255078206,0.401100468,DB0021310054889_,0.91354334,-0.309858429,NA,10054889,Transaminases increased,10022891,Investigations,Inv,pantoprazole,DB00213
,387744,DB08904,10002855,76,11534,15,3544,0.135938737,1.556736324,0.885710258,2.920827167,0.264008866,DB0890410002855_,1.331772592,0.44259153,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,certolizumab pegol,DB08904
,387753,DB08904,10022094,73,11537,13,3546,0.073642988,1.725829311,0.947680789,3.399078773,0.167571825,DB0890410022094_,1.786343214,0.545707695,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,387754,DB08904,10028334,90,11520,25,3534,0.740719939,1.104367296,0.701168113,1.798842085,0.851177039,DB0890410028334_,0.161135136,0.099272588,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,certolizumab pegol,DB08904
,387755,DB08904,10028372,41,11569,9,3550,0.408115369,1.397847392,0.668397486,3.274229751,0.577529003,DB0890410028372_,0.548996615,0.334933476,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,certolizumab pegol,DB08904
,387758,DB08904,10037844,476,11134,127,3432,0.169635517,1.155298598,0.944230745,1.421797212,0.310452189,DB0890410037844_,1.169725372,0.144358837,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,certolizumab pegol,DB08904
,387777,DB00115,10040808,26,18399,34,10438,0.001721289,0.433836534,0.249852873,0.745175066,0.008591734,DB0011510040808_,4.756954738,-0.835087466,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyanocobalamin,DB00115
,387803,DB09038,10005483,19,2229,47,2494,0.002784764,0.452403868,0.249944135,0.788548566,0.012722258,DB0903810005483_,4.364402249,-0.793179986,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,empagliflozin,DB09038
,387959,DB09045,10047895,58,2291,39,1685,0.755207645,1.093802105,0.71268401,1.694607595,0.862620935,DB0904510047895_,0.147779926,0.089659796,NA,10047895,Weight decreased,10022891,Investigations,Inv,dulaglutide,DB09045
,387964,DB00999,10015946,46,21384,13,12226,0.02135149,2.023025324,1.074132422,4.083534436,0.065118515,DB0099910015946_,2.731546362,0.704594076,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,hydrochlorothiazide,DB00999
,388013,DB01222,10003246,55,9219,6,5399,3.09208943262386e-06,5.367153454,2.312699086,15.27129588,3.89064484138431e-05,DB0122210003246_,10.15435055,1.680297685,female,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,budesonide,DB01222
,388139,DB00374,10070617,75,17641,16,5708,0.142761189,1.516647348,0.874963652,2.790784229,0.273663788,DB0037410070617_,1.295854978,0.416502206,NA,10070617,Device infusion issue,10077536,Product issues,Prod,treprostinil,DB00374
,388152,DB00722,10061284,42,25361,19,26013,0.00290766,2.267330562,1.289557038,4.129034713,0.013169269,DB0072210061284_,4.329869248,0.818603176,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,388200,DB00115,10064848,88,18337,58,10414,0.388752364,0.861686178,0.611034822,1.223080643,0.558639581,DB0011510064848_,0.582250771,-0.148864137,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,cyanocobalamin,DB00115
,388323,DB00115,10028164,50,18375,18,10454,0.10125338,1.580323837,0.90549951,2.879888297,0.212719906,DB0011510028164_,1.547778976,0.457629786,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,cyanocobalamin,DB00115
,388370,DB00915,10013573,72,1383,57,994,0.647090564,0.907902424,0.626049758,1.321761136,0.782336391,DB0091510013573_,0.245470464,-0.096618369,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,amantadine,DB00915
,388381,DB00915,10049848,61,1394,38,1013,0.53317016,1.166435731,0.758722383,1.813160062,0.689938592,DB0091510049848_,0.371152682,0.153952715,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,amantadine,DB00915
,388393,DB00051,10027951,40,25691,18,11402,1,0.986251288,0.552274456,1.828493498,1,DB0005110027951_,0,-0.013844101,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,adalimumab,DB00051
,388412,DB00480,10020377,67,67361,34,67628,0.000964343,1.978377901,1.290546122,3.083933281,0.005347626,DB0048010020377_,5.231102487,0.682277267,NA,10020377,Hordeolum,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,388443,DB00215,10013538,41,11062,12,5264,0.143742435,1.625822421,0.837434388,3.401057448,0.275151936,DB0021510013538_,1.290431841,0.486013793,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,citalopram,DB00215
,388517,DB00230,10061225,77,19597,33,8618,1,1.026127658,0.673581301,1.594440114,1,DB0023010061225_,0,0.025792162,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,388692,DB13867,10029331,38,4512,29,2525,0.249265095,0.733350345,0.439238863,1.236105244,0.408678457,DB1386710029331_,0.894826601,-0.310131731,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,fluticasone,DB13867
,388695,DB00264,10061481,30,29577,27,24865,0.792208429,0.934115327,0.536541028,1.633513906,0.88743507,DB0026410061481_,0.119419921,-0.068155372,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,388726,DB00927,10019063,33,7464,27,4989,0.431964807,0.816963479,0.475704015,1.414336924,0.600431933,DB0092710019063_,0.510105994,-0.202160886,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,famotidine,DB00927
,388741,DB00480,10008796,53,67375,38,67624,0.116662911,1.399881967,0.905523688,2.182839616,0.236101373,DB0048010008796_,1.443494021,0.336387923,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,lenalidomide,DB00480
,388747,DB00656,10061822,65,11948,17,6602,0.005181347,2.11265732,1.222589038,3.848134336,0.021048096,DB0065610061822_,3.860945169,0.747946549,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,388783,DB01065,10029331,47,4284,43,3008,0.236203717,0.767500487,0.495218625,1.192154192,0.393435867,DB0106510029331_,0.932837206,-0.264616165,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,melatonin,DB01065
,388793,DB00480,10016326,68,67360,44,67618,0.023260574,1.55136003,1.046211175,2.321606857,0.069485644,DB0048010016326_,2.666635108,0.439131985,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,388833,DB01156,10016807,37,13585,15,6313,0.765881224,1.146254233,0.613571586,2.249906665,0.870952149,DB0115610016807_,0.138168242,0.136499437,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,bupropion,DB01156
,388943,DB08895,10051055,62,28052,30,6616,0.002014671,0.487415858,0.310148939,0.781613573,0.009785759,DB0889510051055_,4.626827101,-0.718637603,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,tofacitinib,DB08895
,388947,DB00678,10069868,32,15567,20,10704,0.779230511,1.100191121,0.609841457,2.030887891,0.879700811,DB0067810069868_,0.128173417,0.095483911,NA,10069868,Device issue,10077536,Product issues,Prod,losartan,DB00678
,389002,DB00472,10029354,38,10721,25,4287,0.068050111,0.607823619,0.356985279,1.051955762,0.157782134,DB0047210029354_,1.846540097,-0.49787054,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,fluoxetine,DB00472
,389045,DB00115,10048865,55,18370,29,10443,0.820462597,1.078159014,0.675177377,1.754783165,0.904351949,DB0011510048865_,0.10053667,0.07525497,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,cyanocobalamin,DB00115
,389076,DB00338,10058920,64,33610,18,22254,0.000937517,2.354175658,1.377508054,4.222211798,0.005222002,DB0033810058920_,5.254874459,0.856190627,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,389166,DB00874,10061428,48,3287,38,1938,0.178886213,0.744813343,0.474595651,1.176134968,0.322520345,DB0087410061428_,1.13158906,-0.294621639,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,guaifenesin,DB00874
,389192,DB01377,10013700,36,3760,17,2653,0.207373093,1.494090013,0.815747122,2.842971312,0.358067277,DB0137710013700_,1.027034385,0.401517335,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,magnesium oxide,DB01377
,389221,DB01234,10016338,75,31550,35,32853,5.3443425056123e-05,2.231339149,1.474529564,3.436393051,0.000467163,DB0123410016338_,7.668831409,0.802601921,NA,10016338,Feeling jittery,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,389242,DB00338,10061016,34,33640,26,22246,0.599040106,0.864777396,0.503648791,1.501089387,0.743742345,DB0033810061016_,0.296060615,-0.145283151,NA,10061016,Blood test abnormal,10022891,Investigations,Inv,omeprazole,DB00338
,389248,DB00836,10007739,46,5489,19,4056,0.032352122,1.788884097,1.025866387,3.238327744,0.089863207,DB0083610007739_,2.409466684,0.581592016,NA,10007739,Cataract,10015919,Eye disorders,Eye,loperamide,DB00836
,389276,DB00540,10053762,68,2415,28,1063,0.822906201,1.068953077,0.674529925,1.735088566,0.906029258,DB0054010053762_,0.09868368,0.066679737,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,nortriptyline,DB00540
,389292,DB14500,10020751,63,7746,18,4055,0.024987814,1.832151811,1.06940299,3.292740019,0.073439335,DB1450010020751_,2.611295593,0.605491129,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,potassium,DB14500
,389304,DB00370,10028810,34,4507,16,3647,0.086242581,1.719407489,0.92181987,3.341842854,0.188764847,DB0037010028810_,1.667253233,0.541979749,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,mirtazapine,DB00370
,389321,DB00641,10029366,32,14092,30,12445,0.898769934,0.942032606,0.553969937,1.605765298,0.95647837,DB0064110029366_,0.044497104,-0.059715391,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,simvastatin,DB00641
,389325,DB00654,10003658,30,3786,30,2568,0.146508215,0.67834634,0.394007046,1.167800315,0.279045552,DB0065410003658_,1.27638024,-0.388097296,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,latanoprost,DB00654
,389329,DB00169,10005619,63,38628,18,18157,0.0728785,1.645153495,0.961471703,2.953357017,0.166336245,DB0016910005619_,1.793743966,0.49783369,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,cholecalciferol,DB00169
,389341,DB00047,10017413,32,9253,43,8475,0.105646488,0.681633843,0.417018391,1.103748021,0.219608751,DB0004710017413_,1.515907719,-0.383262653,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,insulin glargine,DB00047
,389443,DB00121,10011224,89,4134,15,453,0.134744157,0.650243274,0.369923713,1.220858663,0.262254734,DB0012110011224_,1.338438981,-0.430408718,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,biotin,DB00121
,389511,DB06262,10000087,65,3735,33,4281,0.000138039,2.257428052,1.45924327,3.552309269,0.001050023,DB0626210000087_,6.858943453,0.814226135,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,droxidopa,DB06262
,389513,DB06262,10028813,321,3479,132,4182,2.51339592269233e-26,2.922845597,2.366889635,3.625554699,4.2760266555319e-24,DB0626210028813_,53.809018,1.072557661,female,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,droxidopa,DB06262
,389564,DB01217,10016173,74,2680,8,260,0.695225635,0.897440552,0.426170201,2.179727151,0.816560818,DB0121710016173_,0.202653883,-0.108208398,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,anastrozole,DB01217
,389596,DB00863,10013786,56,10617,28,5812,0.732839814,1.094851718,0.682931335,1.792259902,0.844910609,DB0086310013786_,0.168524445,0.090618937,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,ranitidine,DB00863
,389685,DB01067,10022000,42,4319,37,4786,0.31158457,1.257837943,0.787530707,2.016523923,0.479025691,DB0106710022000_,0.736001048,0.229394329,NA,10022000,Influenza,10021881,Infections and infestations,Infec,glipizide,DB01067
,389689,DB00190,10028334,40,3257,24,4650,0.000794562,2.379243611,1.396576658,4.134726102,0.004549129,DB0019010028334_,5.392819428,0.866782627,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,carbidopa,DB00190
,389695,DB00787,10029148,29,16971,37,17211,0.38941805,0.794874841,0.471257366,1.328891016,0.559336253,DB0078710029148_,0.581004461,-0.229570609,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,acyclovir,DB00787
,389700,DB00437,10013786,27,6894,52,11494,0.641509841,0.865670285,0.522261731,1.405306038,0.778196614,DB0043710013786_,0.250776069,-0.144251176,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,389730,DB00581,10038435,20,2093,34,2035,0.054596385,0.572013523,0.310870611,1.026524051,0.133612585,DB0058110038435_,2.01281082,-0.558592647,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,lactulose,DB00581
,389732,DB00295,10023547,31,14632,33,9569,0.054929063,0.614374754,0.36362979,1.035548318,0.13420807,DB0029510023547_,2.008363924,-0.487150189,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,morphine,DB00295
,389855,DB00480,10041232,82,67346,40,67622,0.000127957,2.058379445,1.393801546,3.084456698,0.00098444,DB0048010041232_,6.923437682,0.721918996,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,389858,DB00737,10010774,70,2731,16,916,0.206903854,1.467231213,0.838346561,2.720944048,0.35754831,DB0073710010774_,1.028484792,0.383377096,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,meclizine,DB00737
,389890,DB00480,10018879,33,67395,27,67635,0.441772839,1.226570648,0.715120848,2.120830452,0.609894929,DB0048010018879_,0.494468584,0.204222185,NA,10018879,Haemoglobin abnormal,10022891,Investigations,Inv,lenalidomide,DB00480
,389891,DB01234,10023681,33,31592,20,32868,0.05544867,1.71661669,0.956037723,3.15769049,0.135069579,DB0123410023681_,2.00196523,0.540355313,NA,10023681,Lactose intolerance,10027433,Metabolism and nutrition disorders,Metab,dexamethasone,DB01234
,389904,DB00863,10062355,68,10605,23,5817,0.04752216,1.621651801,0.996500589,2.730037038,0.120448026,DB0086310062355_,2.116536937,0.48344526,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,ranitidine,DB00863
,389919,DB01373,10018836,50,22670,15,7366,0.885668069,1.083072789,0.597992985,2.078083433,0.952411128,DB0137310018836_,0.04875848,0.079802177,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,calcium,DB01373
,389968,DB00231,10022000,39,3257,13,2126,0.032983599,1.958018139,1.020237286,4.007619484,0.091241202,DB0023110022000_,2.394248712,0.671932808,NA,10022000,Influenza,10021881,Infections and infestations,Infec,temazepam,DB00231
,389980,DB00188,10029223,31,7855,31,8797,0.703018427,1.11991522,0.657756636,1.906904837,0.821800601,DB0018810029223_,0.196257491,0.113252986,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,bortezomib,DB00188
,389983,DB01234,10029223,65,31560,48,32840,0.073900533,1.409073811,0.955191024,2.091520825,0.168012414,DB0123410029223_,1.783717412,0.342932617,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,390108,DB00480,10061414,34,67394,36,67626,0.904959883,0.947677523,0.575217364,1.558286639,0.957667115,DB0048010061414_,0.043255041,-0.053741,NA,10061414,White blood cell disorder,10005329,Blood and lymphatic system disorders,Blood,lenalidomide,DB00480
,390149,DB00480,10073317,38,67390,15,67647,0.001466819,2.543112957,1.366431728,4.976834579,0.007550989,DB0048010073317_,4.886076772,0.933388904,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,390181,DB00188,10040844,35,7851,29,8799,0.259235531,1.352595673,0.802359763,2.296254151,0.420357865,DB0018810040844_,0.866648871,0.302025467,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,bortezomib,DB00188
,390210,DB00480,10033474,41,67387,21,67641,0.010992463,1.959719037,1.131451779,3.491130004,0.038391827,DB0048010033474_,3.259910685,0.672801115,NA,10033474,Pain of skin,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,390221,DB13961,10038428,35,9422,29,6385,0.445215221,0.817893387,0.485119526,1.388643979,0.613241214,DB1396110038428_,0.488996923,-0.201023285,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,fish oil,DB13961
,390321,DB00480,10033733,90,67338,57,67605,0.006370902,1.585193273,1.124949907,2.249805062,0.02484373,DB0048010033733_,3.695149871,0.460706339,NA,10033733,Papule,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,390347,DB00316,10036000,38,65436,16,36937,0.395379512,1.340624859,0.729779518,2.575704638,0.565042842,DB0031610036000_,0.570853723,0.293135818,NA,10036000,Poisoning deliberate,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,390357,DB00497,10024774,43,19224,50,16325,0.144708937,0.73032305,0.474011428,1.121006608,0.276610748,DB0049710024774_,1.285144002,-0.314268308,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,oxycodone,DB00497
,390362,DB00182,10022086,53,5141,15,2837,0.021498945,1.949683027,1.080280103,3.731288958,0.06545431,DB0018210022086_,2.726402945,0.667666809,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,390372,DB13867,10008531,49,4501,14,2540,0.024422148,1.974946705,1.070425117,3.881635754,0.072229103,DB1386710008531_,2.627912222,0.680541413,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,390383,DB00874,10028411,34,3301,26,1950,0.347974544,0.77254695,0.44853327,1.345006575,0.517570784,DB0087410028411_,0.658608983,-0.258062496,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,guaifenesin,DB00874
,390402,DB00480,10024570,56,67372,36,67626,0.037147302,1.56140606,1.009127332,2.443918722,0.099878971,DB0048010024570_,2.303796113,0.445586736,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,390421,DB00188,10056819,33,7853,17,8811,0.009985648,2.17789784,1.177697658,4.172504174,0.035524498,DB0018810056819_,3.337532727,0.778360118,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,390426,DB00787,10056819,69,16931,54,17194,0.17520431,1.29761256,0.895084396,1.88968769,0.317728535,DB0078710056819_,1.146557926,0.260526084,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,390450,DB00480,10013789,41,67387,14,67648,0.000228417,2.940056789,1.569777773,5.839110162,0.001610932,DB0048010013789_,6.430942137,1.078428897,female,10013789,Dry throat,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,390453,DB01098,10028735,42,8107,15,7194,0.001976438,2.484421182,1.348480083,4.827538381,0.009634867,DB0109810028735_,4.642366772,0.910039708,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,390491,DB01432,10013709,51,1240,37,633,0.134320037,0.703745574,0.44663316,1.118043434,0.261739356,DB0143210013709_,1.340406095,-0.351338389,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,cholestyramine,DB01432
,390542,DB06643,10017413,59,52362,11,7504,0.371244471,0.76866787,0.399741585,1.623585705,0.540888028,DB0664310017413_,0.614542994,-0.263096301,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,denosumab,DB06643
,390616,DB00404,10062244,44,19848,14,9848,0.163581876,1.559372664,0.838235513,3.082625692,0.302224617,DB0040410062244_,1.196584774,0.444283602,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alprazolam,DB00404
,390649,DB00737,10035664,104,2697,30,902,0.542340721,1.159363515,0.759865721,1.816333175,0.697564389,DB0073710035664_,0.360160455,0.147871161,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,meclizine,DB00737
,390651,DB00787,10013946,74,16926,47,17201,0.013609455,1.600016918,1.094607409,2.359306793,0.045509131,DB0078710013946_,3.089842285,0.470014203,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,390657,DB00264,10005619,39,29568,20,24872,0.088335106,1.640281491,0.933413576,2.969177232,0.192480168,DB0026410005619_,1.647762155,0.494867868,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,metoprolol,DB00264
,390758,DB01012,10026882,30,10602,21,8664,0.673020243,1.167424987,0.645997615,2.147048209,0.801555826,DB0101210026882_,0.221200658,0.154800458,NA,10026882,Mastication disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,cinacalcet,DB01012
,390804,DB00480,10012442,41,67387,24,67638,0.035239864,1.714678964,1.01165294,2.967275809,0.09593287,DB0048010012442_,2.344106598,0.53922587,NA,10012442,Dermatitis contact,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,390805,DB01224,10015832,36,8072,34,5883,0.27806554,0.77170914,0.46874944,1.272930576,0.441823489,DB0122410015832_,0.816844822,-0.259147561,NA,10015832,Extrapyramidal disorder,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,390807,DB00073,10066274,17,7389,46,6361,2.10239413040406e-05,0.318173988,0.170830078,0.566348763,0.000208383,DB0007310066274_,8.476133875,-1.145156913,male,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,rituximab,DB00073
,390852,DB00480,10015946,67,67361,32,67630,0.000398345,2.102088913,1.35988688,3.311071188,0.002553782,DB0048010015946_,5.970179739,0.742931571,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,lenalidomide,DB00480
,390872,DB00480,10015929,76,67352,37,67625,0.000220444,2.062357844,1.37461897,3.143475317,0.001563571,DB0048010015929_,6.460782831,0.723849913,NA,10015929,Eye infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,390915,DB13961,10036018,36,9421,32,6382,0.267491888,0.762124376,0.459603579,1.268937521,0.429795481,DB1396110036018_,0.844445808,-0.271645514,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,fish oil,DB13961
,390948,DB00480,10005395,120,67308,88,67574,0.026295918,1.369016935,1.030927295,1.823910784,0.076416607,DB0048010005395_,2.571555236,0.314092917,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,lenalidomide,DB00480
,390965,DB00188,10013774,36,7850,14,8814,0.000529554,2.887033938,1.518167381,5.798180925,0.003234796,DB0018810013774_,5.733789353,1.060229656,female,10013774,Dry eye,10015919,Eye disorders,Eye,bortezomib,DB00188
,390996,DB00927,10023547,47,7450,36,4980,0.574774164,0.87271932,0.552510705,1.388913948,0.724415181,DB0092710023547_,0.322390597,-0.136141287,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,famotidine,DB00927
,391016,DB00335,10022000,79,8387,35,5430,0.067118124,1.461304599,0.968276068,2.245826059,0.156192996,DB0033510022000_,1.85666288,0.379329598,NA,10022000,Influenza,10021881,Infections and infestations,Infec,atenolol,DB00335
,391072,DB01068,10036790,38,13725,12,6828,0.179280591,1.575341339,0.805264249,3.313659335,0.322965549,DB0106810036790_,1.13020962,0.454471972,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,391081,DB00091,10007739,49,5461,9,2661,0.004568667,2.652673714,1.286974211,6.151747397,0.018998166,DB0009110007739_,3.963412813,0.97556808,NA,10007739,Cataract,10015919,Eye disorders,Eye,cyclosporine,DB00091
,391219,DB00437,10040829,35,6886,36,11510,0.048659006,1.624962958,0.989787708,2.665444511,0.122556725,DB0043710040829_,2.099181298,0.48548502,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,allopurinol,DB00437
,391244,DB01234,10039203,34,31591,24,32864,0.150334684,1.473735512,0.848408774,2.598219846,0.28441697,DB0123410039203_,1.257313913,0.387800342,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,391296,DB09079,10011906,46,611,60,817,0.919218488,1.025142893,0.672476772,1.554251257,0.964295004,DB0907910011906_,0.03635801,0.024832011,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,nintedanib,DB09079
,391347,DB00704,10037844,60,4296,52,5142,0.104397962,1.381011261,0.934447663,2.046922525,0.217587157,DB0070410037844_,1.525155788,0.322816029,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,naltrexone,DB00704
,391355,DB00704,10048959,41,4315,31,5163,0.057526076,1.582403061,0.966573389,2.614795272,0.138792317,DB0070410048959_,1.974776585,0.458944617,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,391395,DB01234,10037153,30,31595,23,32865,0.275462122,1.356765444,0.761833021,2.446360146,0.438766325,DB0123410037153_,0.823788298,0.305103517,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,391396,DB00787,10043521,30,16970,22,17226,0.268482532,1.384188434,0.771842488,2.519653647,0.430942554,DB0078710043521_,0.841780483,0.325113999,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acyclovir,DB00787
,391402,DB08911,10051398,86,1553,101,1647,0.547158369,0.903058003,0.663557394,1.226796307,0.701783273,DB0891110051398_,0.354130651,-0.101968494,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,trametinib,DB08911
,391426,DB00421,10052904,40,8863,20,5232,0.594101602,1.180660805,0.673246403,2.134145022,0.740127997,DB0042110052904_,0.300932139,0.166074286,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,spironolactone,DB00421
,391565,DB01156,10050584,69,13553,19,6309,0.050186176,1.690480935,1.004434052,2.978218539,0.125364089,DB0115610050584_,2.07653306,0.525013066,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,391566,DB06403,10050584,105,21366,21,6640,0.073483847,1.553813187,0.965024331,2.616889614,0.167332835,DB0640310050584_,1.787770427,0.440712031,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,ambrisentan,DB06403
,391567,DB08931,10050584,85,6492,19,2427,0.045308207,1.672433169,1.005521912,2.919740027,0.11617659,DB0893110050584_,2.152643916,0.514279553,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,riociguat,DB08931
,391593,DB01175,10017944,47,10677,13,4879,0.124785142,1.652051136,0.878335418,3.331478603,0.248257453,DB0117510017944_,1.393288955,0.502017628,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,escitalopram,DB01175
,391642,DB00836,10039906,43,5492,45,4030,0.10430237,0.701218949,0.449776379,1.091869721,0.217470442,DB0083610039906_,1.525692335,-0.354935103,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,391772,DB00455,10016766,39,9362,21,5097,1,1.011092877,0.579613477,1.811138258,1,DB0045510016766_,0,0.011031802,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,loratadine,DB00455
,391965,DB00190,10073085,81,3216,111,4563,0.824191965,1.035387855,0.764878007,1.396524548,0.906856118,DB0019010073085_,0.097771477,0.034776095,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,carbidopa,DB00190
,392105,DB00563,10024384,224,46422,82,15266,0.425512346,0.89831844,0.694096178,1.172352411,0.594235086,DB0056310024384_,0.520480271,-0.107230663,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,methotrexate,DB00563
,392158,DB00874,10000059,37,3298,19,1957,0.677944157,1.155547605,0.645618795,2.133523006,0.80481278,DB0087410000059_,0.2171456,0.144574348,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,guaifenesin,DB00874
,392207,DB00531,10048610,37,7215,15,6501,0.007891974,2.222357571,1.189347565,4.363074186,0.029459707,DB0053110048610_,3.524731812,0.798568601,NA,10048610,Cardiotoxicity,10007541,Cardiac disorders,Card,cyclophosphamide,DB00531
,392233,DB00542,10070863,32,1654,18,1406,0.197638665,1.511019529,0.818850214,2.872353363,0.346121147,DB0054210070863_,1.060966429,0.412784608,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,benazepril,DB00542
,392239,DB00829,10038678,42,8010,40,4414,0.014867221,0.578612487,0.365618965,0.917059691,0.048963948,DB0082910038678_,3.016671006,-0.547122305,NA,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diazepam,DB00829
,392269,DB08932,10040943,54,19389,12,6585,0.203788405,1.528246697,0.806858846,3.140865445,0.353577999,DB0893210040943_,1.039651171,0.424121129,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,macitentan,DB08932
,392345,DB00480,10057371,87,67341,41,67621,4.12220800823405e-05,2.130751645,1.453542572,3.169102656,0.000374209,DB0048010057371_,7.890695894,0.756474803,NA,10057371,Hypoaesthesia oral,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,392358,DB00321,10051118,47,7400,18,2832,1,0.999252204,0.56835509,1.831461906,1,DB0032110051118_,0,-0.000748076,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,amitriptyline,DB00321
,392421,DB00243,10013709,45,1209,39,1587,0.073400706,1.514354882,0.957467019,2.404482791,0.167186964,DB0024310013709_,1.788642546,0.414989528,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ranolazine,DB00243
,392461,DB01212,10003481,30,1989,75,1866,3.77519141147184e-06,0.375351742,0.236058554,0.583425547,4.61539098839709e-05,DB0121210003481_,9.983528879,-0.979891715,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,ceftriaxone,DB01212
,392520,DB00904,10018092,31,23038,20,14436,1,0.971239925,0.53603326,1.798659263,1,DB0090410018092_,0,-0.029181751,NA,10018092,Generalised oedema,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,392607,DB00795,10017577,44,4525,15,1488,0.880161234,0.96460028,0.524747983,1.871623636,0.949694712,DB0079510017577_,0.051614701,-0.036041481,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,392621,DB00635,10014581,24,33029,47,23747,5.16339376701627e-05,0.367141208,0.214639306,0.612848612,0.000453761,DB0063510014581_,7.69794074,-1.002008742,male,10014581,Encephalitis,10021881,Infections and infestations,Infec,prednisone,DB00635
,392645,DB00697,10029331,72,6024,23,1783,0.713871332,0.926554799,0.570527101,1.557708744,0.83029176,DB0069710029331_,0.185978122,-0.076282089,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,tizanidine,DB00697
,392660,DB00051,10020096,63,25668,26,11394,0.818649079,1.075598381,0.67082278,1.770975454,0.90321487,DB0005110020096_,0.101794803,0.07287714,NA,10020096,Hip arthroplasty,10042613,Surgical and medical procedures,Surg,adalimumab,DB00051
,392711,DB00186,10065154,53,16848,37,9971,0.446030774,0.84775523,0.546247234,1.328103114,0.613882024,DB0018610065154_,0.487952513,-0.165163328,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,lorazepam,DB00186
,392712,DB00814,10065154,82,8205,25,3390,0.200718459,1.355094976,0.855179667,2.21801933,0.349824931,DB0081410065154_,1.050322448,0.303871545,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,meloxicam,DB00814
,392713,DB06285,10065154,338,8512,39,1067,0.676735458,1.086395016,0.773003018,1.564538791,0.803963008,DB0628510065154_,0.218202021,0.08286489,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,teriparatide,DB06285
,392718,DB00338,10019194,55,33619,14,22258,0.000777766,2.600919835,1.426492355,5.065737243,0.004467566,DB0033810019194_,5.410911579,0.955865165,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,392734,DB09027,10025482,36,5143,36,7116,0.187897324,1.383570867,0.845840727,2.263196086,0.333950866,DB0902710025482_,1.096761405,0.324667742,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,392735,DB09027,10027175,53,5126,47,7105,0.032138971,1.5629251,1.03350487,2.370193623,0.089398683,DB0902710027175_,2.414649326,0.44655913,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ledipasvir,DB09027
,392738,DB00222,10022000,32,3174,24,3104,0.349603527,1.303869961,0.74231944,2.319127436,0.519229783,DB0022210022000_,0.655408752,0.265336735,NA,10022000,Influenza,10021881,Infections and infestations,Infec,glimepiride,DB00222
,392780,DB09034,10019211,84,1092,22,656,0.000379858,2.292793885,1.403653414,3.891174981,0.002456531,DB0903410019211_,6.009005116,0.829771111,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,suvorexant,DB09034
,392791,DB06317,10011906,34,569,37,683,0.714392672,1.102942909,0.662109876,1.83246917,0.830692828,DB0631710011906_,0.185495194,0.097981979,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,elotuzumab,DB06317
,392847,DB09052,10010305,19,910,45,1014,0.007043123,0.470663569,0.257931709,0.82820341,0.026923864,DB0905210010305_,3.61474223,-0.753611731,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,blinatumomab,DB09052
,392848,DB09052,10052015,47,882,61,998,0.552061982,0.871886636,0.576441164,1.311798744,0.705905636,DB0905210052015_,0.348273711,-0.137095868,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,blinatumomab,DB09052
,392856,DB09052,10016288,20,909,32,1027,0.260614815,0.706256419,0.379926995,1.283578102,0.422086966,DB0905210016288_,0.862543905,-0.347776908,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,blinatumomab,DB09052
,392859,DB01012,10061822,43,10589,33,8652,0.818142849,1.064685561,0.660130228,1.73135657,0.902926851,DB0101210061822_,0.102113735,0.062679508,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,392873,DB04951,10003549,63,1819,97,2960,0.74118349,1.056870361,0.752902063,1.474730609,0.851523582,DB0495110003549_,0.160728085,0.055312051,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pirfenidone,DB04951
,392875,DB04951,10011224,68,1814,97,2960,0.415459338,1.143873082,0.821634603,1.585068487,0.584686829,DB0495110011224_,0.53667891,0.134419945,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pirfenidone,DB04951
,392876,DB04951,10013946,55,1827,60,2997,0.032575901,1.503512788,1.018564423,2.215775431,0.090365423,DB0495110013946_,2.403893573,0.407804229,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,pirfenidone,DB04951
,392879,DB04951,10028813,326,1556,227,2830,7.70227054439396e-26,2.611438982,2.172672669,3.142849516,1.24971716826787e-23,DB0495110028813_,52.73653988,0.959901404,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pirfenidone,DB04951
,392903,DB01012,10056819,43,10589,38,8647,0.738144519,0.924054199,0.582712863,1.470558598,0.849219971,DB0101210056819_,0.163437032,-0.078984553,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,cinacalcet,DB01012
,392974,DB09034,10029412,49,1127,38,640,0.171614072,0.73241507,0.464074407,1.163444997,0.312923747,DB0903410029412_,1.161795739,-0.31140789,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,suvorexant,DB09034
,392977,DB08904,10000087,99,11511,27,3532,0.672951811,1.125059211,0.727489284,1.794738314,0.801528802,DB0890410000087_,0.221234373,0.117835666,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,certolizumab pegol,DB08904
,392979,DB08904,10008531,49,11561,17,3542,0.66279553,0.883071139,0.498983784,1.637852775,0.794417715,DB0890410008531_,0.230145866,-0.124349517,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,393017,DB11089,10042609,32,10143,21,8386,0.490026342,1.259834145,0.703801888,2.300683049,0.653360171,DB1108910042609_,0.425626739,0.230980082,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,docusate,DB11089
,393030,DB01012,10013700,39,10593,26,8659,0.455332219,1.226126247,0.727073284,2.099587837,0.622831954,DB0101210013700_,0.473478533,0.203859807,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,cinacalcet,DB01012
,393035,DB05676,10007882,88,47041,47,25282,1,1.006281945,0.698192592,1.466569222,1,DB0567610007882_,0,0.006262295,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,apremilast,DB05676
,393102,DB01065,10054112,53,4278,30,3021,0.370728552,1.247531839,0.780576792,2.027610952,0.54042093,DB0106510054112_,0.615406943,0.22116707,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,melatonin,DB01065
,393174,DB01220,10047700,46,1248,37,1099,0.737577556,1.09474029,0.68899787,1.74991624,0.848772019,DB0122010047700_,0.163964658,0.090517157,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,rifaximin,DB01220
,393288,DB00909,10016173,31,789,21,460,0.660523127,0.860749668,0.472672324,1.596138506,0.792760457,DB0090910016173_,0.232234175,-0.149951562,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,zonisamide,DB00909
,393292,DB00904,10016334,62,23007,24,14432,0.045761244,1.620471344,0.99635045,2.716097881,0.117018611,DB0090410016334_,2.145422285,0.48271706,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,393397,DB00281,10058080,59,11399,32,5639,0.656949168,0.912096916,0.582714418,1.451529848,0.790257145,DB0028110058080_,0.235396886,-0.092009027,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,lidocaine,DB00281
,393402,DB09052,10011906,32,897,37,1022,1,0.985392781,0.588872212,1.640884741,1,DB0905210011906_,0,-0.014714955,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,blinatumomab,DB09052
,393411,DB00704,10039906,32,4324,41,5153,0.814012517,0.930110196,0.565898006,1.516545998,0.900234312,DB0070410039906_,0.105100203,-0.07245221,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,naltrexone,DB00704
,393523,DB00788,10065154,48,9308,28,5033,0.80970547,0.926950723,0.569109082,1.53639768,0.897453438,DB0078810065154_,0.10819404,-0.075854872,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,naproxen,DB00788
,393524,DB00829,10065154,36,8016,16,4438,0.56203763,1.245717485,0.672974607,2.407098676,0.714334853,DB0082910065154_,0.336403444,0.219711657,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,diazepam,DB00829
,393599,DB00043,10002855,99,6314,24,2276,0.098580787,1.486816091,0.941422228,2.435645982,0.208748569,DB0004310002855_,1.56662477,0.396636982,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,omalizumab,DB00043
,393825,DB09027,10070218,23,5156,42,7110,0.314418027,0.755170785,0.432922662,1.286643159,0.482006172,DB0902710070218_,0.729798359,-0.280811349,NA,10070218,Hepatitis C virus test positive,10022891,Investigations,Inv,ledipasvir,DB09027
,393863,DB00836,10023547,34,5501,28,4047,0.699704902,0.893342925,0.524825508,1.532021906,0.819545349,DB0083610023547_,0.199005545,-0.112784757,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,loperamide,DB00836
,393878,DB01012,10017944,72,10560,54,8631,0.654279545,1.089797773,0.754242907,1.582725923,0.788109792,DB0101210017944_,0.238117869,0.08599215,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,cinacalcet,DB01012
,393946,DB00813,10013663,35,10537,57,10111,0.015797731,0.589229476,0.375005554,0.914129419,0.051343846,DB0081310013663_,2.969210189,-0.528939569,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,fentanyl,DB00813
,394166,DB00997,10010264,44,5287,17,3497,0.065698171,1.711846106,0.956691027,3.201265388,0.153637195,DB0099710010264_,1.873161335,0.537572383,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,394215,DB09034,10022437,94,1082,37,641,0.047756973,1.504755342,1.004435198,2.294350513,0.120892959,DB0903410022437_,2.112849763,0.408630322,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,suvorexant,DB09034
,394302,DB08932,10027599,229,19214,28,6569,8.39203782294923e-09,2.796217063,1.881622606,4.305756147,1.91979733834831e-07,DB0893210027599_,15.46587602,1.028267455,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,394428,DB00668,10053483,126,9965,38,4265,0.059385029,1.419165185,0.978451428,2.101133062,0.142343197,DB0066810053483_,1.949514259,0.350068801,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,394437,DB00904,10053483,40,23029,13,14443,0.046873896,1.929705951,1.010656323,3.933999757,0.119217913,DB0090410053483_,2.126802255,0.657367634,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,394495,DB08931,10038776,52,6525,10,2436,0.061189524,1.941252268,0.973967801,4.291130438,0.145627997,DB0893110038776_,1.926699878,0.663333264,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,394496,DB08932,10038776,71,19372,12,6585,0.022362604,2.011280335,1.081823258,4.077587746,0.067437627,DB0893210038776_,2.69655215,0.698771502,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,394504,DB01073,10025256,74,991,96,1554,0.256081378,1.208658031,0.870743284,1.672411479,0.416850844,DB0107310025256_,0.875026809,0.189510679,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,fludarabine,DB01073
,394521,DB00829,10000381,28,8024,36,4418,0.000913074,0.42826974,0.251353699,0.722818627,0.005113487,DB0082910000381_,5.275873636,-0.848002049,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,394577,DB00996,10013722,46,38907,24,22401,0.804026158,1.103546713,0.659584281,1.89072677,0.89404042,DB0099610013722_,0.112004292,0.098529278,NA,10013722,Drug level increased,10022891,Investigations,Inv,gabapentin,DB00996
,394653,DB01075,10048908,52,19896,22,11075,0.331472945,1.315702301,0.784725143,2.276334052,0.500259315,DB0107510048908_,0.692628685,0.274370592,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,diphenhydramine,DB01075
,394754,DB00927,10010144,47,7450,10,5006,0.00035273,3.157878917,1.572946255,7.016550288,0.002307492,DB0092710010144_,6.07159418,1.149900574,female,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,famotidine,DB00927
,394790,DB09183,10037844,38,437,27,700,0.001648,2.252866408,1.318744393,3.896097059,0.008297609,DB0918310037844_,4.791787821,0.812203365,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dasabuvir,DB09183
,394835,DB00480,10057372,52,67376,11,67651,9.54937525996904e-08,4.746304578,2.446429005,10.09005565,1.73406099280336e-06,DB0048010057372_,13.26504451,1.557366332,female,10057372,Paraesthesia oral,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,394885,DB00820,10013578,42,11873,21,5795,0.894064963,0.976147237,0.564596728,1.736801582,0.955860142,DB0082010013578_,0.045143671,-0.024141847,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,394966,DB00230,10024774,43,19631,30,8621,0.056190054,0.629462903,0.3855352,1.039962456,0.136426711,DB0023010024774_,1.991967725,-0.462888358,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,pregabalin,DB00230
,395088,DB00443,10012735,133,2013,99,1091,0.022962756,0.728208366,0.551112431,0.964649157,0.068823203,DB0044310012735_,2.676214339,-0.317168055,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,betamethasone,DB00443
,395189,DB09034,10028813,53,1123,14,664,0.006391662,2.237534761,1.212386478,4.401962471,0.024906211,DB0903410028813_,3.692638069,0.805374707,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,suvorexant,DB09034
,395191,DB09034,10062519,37,1139,27,651,0.356782662,0.783361953,0.459464247,1.351114595,0.526456467,DB0903410062519_,0.641586635,-0.244160425,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,suvorexant,DB09034
,395196,DB01076,10007556,22,25725,42,25541,0.012199244,0.520072531,0.295586239,0.891502363,0.041703359,DB0107610007556_,3.177173608,-0.653786994,NA,10007556,Cardiac failure acute,10007541,Cardiac disorders,Card,atorvastatin,DB01076
,395255,DB00641,10037162,52,14072,37,12438,0.339238557,1.242202311,0.798789651,1.949187579,0.508359822,DB0064110037162_,0.67656577,0.216885861,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,simvastatin,DB00641
,395277,DB00571,10014011,48,5075,14,2595,0.078557661,1.753016713,0.948526825,3.449377428,0.175920364,DB0057110014011_,1.737723864,0.56133814,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,propranolol,DB00571
,395292,DB00434,10016256,35,580,18,540,0.048565533,1.809449924,0.983764892,3.436900589,0.122362332,DB0043410016256_,2.100768701,0.59302289,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,cyproheptadine,DB00434
,395324,DB09140,10013700,42,3699,16,1782,0.4826555,1.26450698,0.693934557,2.416330881,0.646993003,DB0914010013700_,0.435419798,0.234682307,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,oxygen,DB09140
,395325,DB04951,10016256,164,1718,225,2832,0.091764802,1.201465045,0.967572667,1.489486304,0.198075881,DB0495110016256_,1.619105084,0.183541683,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pirfenidone,DB04951
,395326,DB04951,10025482,86,1796,70,2987,1.61024227504605e-05,2.04301612,1.464278612,2.858557271,0.000164786,DB0495110025482_,8.710864453,0.714427206,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,pirfenidone,DB04951
,395330,DB04951,10037087,38,1844,71,2986,0.549779967,0.866669306,0.566001274,1.309018444,0.704135186,DB0495110037087_,0.350784915,-0.143097799,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,pirfenidone,DB04951
,395339,DB08932,10041052,35,19408,15,6582,0.420483528,0.791326079,0.420828806,1.560633468,0.589430405,DB0893210041052_,0.528598623,-0.23404516,NA,10041052,Sluggishness,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,395478,DB08820,10019211,125,4276,75,3470,0.043570477,1.352457658,1.003978095,1.832238091,0.112754749,DB0882010019211_,2.182540184,0.301923425,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ivacaftor,DB08820
,395579,DB00190,10049848,67,3230,110,4564,0.355097795,0.860682483,0.62330906,1.180918276,0.524891985,DB0019010049848_,0.644562781,-0.150029619,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,395661,DB00073,10054236,25,7381,31,6376,0.182223819,0.696669099,0.393913702,1.220590604,0.326666877,DB0007310054236_,1.118814353,-0.361444731,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,rituximab,DB00073
,395674,DB06605,10037423,96,13977,59,12974,0.012443558,1.510326952,1.079867705,2.127555091,0.042367735,DB0660510037423_,3.161368184,0.412326152,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,395831,DB00537,10021036,53,7504,18,4280,0.06284845,1.679332239,0.9664579,3.050606393,0.148698838,DB0053710021036_,1.905832237,0.518396238,NA,10021036,Hyponatraemia,10027433,Metabolism and nutrition disorders,Metab,ciprofloxacin,DB00537
,395840,DB00836,10029366,39,5496,18,4057,0.107364271,1.599297033,0.891839222,2.974810771,0.222218974,DB0083610029366_,1.504092012,0.469564178,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,loperamide,DB00836
,395890,DB08889,10028810,65,3100,49,3836,0.010150516,1.641333648,1.111806709,2.43669801,0.035992864,DB0888910028810_,3.32443458,0.495509111,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,carfilzomib,DB08889
,395926,DB09270,10044565,43,3071,23,2345,0.210937853,1.427498783,0.838633265,2.488958739,0.362409404,DB0927010044565_,1.014980756,0.35592381,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,ubidecarenone,DB09270
,395954,DB08910,10025082,31,16713,25,17463,0.351693932,1.295631188,0.740003433,2.28983979,0.521406565,DB0891010025082_,0.651225186,0.25899798,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pomalidomide,DB08910
,395956,DB09065,10012735,18,734,76,1861,0.060632813,0.600596239,0.335574415,1.022594004,0.144591419,DB0906510012735_,1.933843312,-0.509832385,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,cobicistat,DB09065
,395987,DB00695,10058920,50,27999,18,20510,0.00942064,2.034752143,1.166239235,3.707054646,0.033934703,DB0069510058920_,3.383317112,0.710374014,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,furosemide,DB00695
,396086,DB00402,10013573,36,1316,17,679,0.883398629,1.092577824,0.592901794,2.090457266,0.951268864,DB0040210013573_,0.04995854,0.08853988,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,eszopiclone,DB00402
,396088,DB09029,10016256,365,10979,152,7118,3.68544634409558e-06,1.556805056,1.281791327,1.898238465,4.52355625283924e-05,DB0902910016256_,10.003627,0.44263568,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,396166,DB01394,10030124,34,1406,27,1976,0.035279838,1.76942646,1.031042273,3.064534787,0.096006889,DB0139410030124_,2.343335334,0.57065546,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,colchicine,DB01394
,396248,DB00186,10029216,71,16830,19,9989,0.001404268,2.217841382,1.320833965,3.900110383,0.007276006,DB0018610029216_,4.923173137,0.796534372,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,lorazepam,DB00186
,396254,DB00904,10029216,60,23009,25,14431,0.09411185,1.505238162,0.929112874,2.506551147,0.201927627,DB0090410029216_,1.599845929,0.408951133,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,396461,DB00572,10012378,39,2863,22,2104,0.362581507,1.30269787,0.750935265,2.314154573,0.53220767,DB0057210012378_,0.630721509,0.264437399,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,atropine,DB00572
,396860,DB00198,10025482,38,1237,18,985,0.076805285,1.68066873,0.929207495,3.14900555,0.172875363,DB0019810025482_,1.75518439,0.519191768,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,oseltamivir,DB00198
,396919,DB00863,10001949,47,10626,20,5820,0.372696383,1.28713415,0.747116024,2.295527374,0.542420951,DB0086310001949_,0.611712916,0.252418158,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,396949,DB01234,10018870,36,31589,36,32852,0.906433302,1.039994135,0.636550895,1.699071469,0.958224861,DB0123410018870_,0.042672809,0.039215074,NA,10018870,Blood urine present,10022891,Investigations,Inv,dexamethasone,DB01234
,397003,DB00422,10048959,36,3399,14,2935,0.010056704,2.220076478,1.165805021,4.465076778,0.035728928,DB0042210048959_,3.331794604,0.797541645,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,397074,DB00620,10008531,41,4787,15,3117,0.055385166,1.779656097,0.962479998,3.467332988,0.134983823,DB0062010008531_,2.00260034,0.576420142,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,triamcinolone,DB00620
,397103,DB00620,10046306,55,4773,36,3096,1,0.990990483,0.637659138,1.557043371,1,DB0062010046306_,0,-0.009050348,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,triamcinolone,DB00620
,397296,DB00904,10027457,44,23025,17,14439,0.113245339,1.623063819,0.908406386,3.031302177,0.230954241,DB0090410027457_,1.465535679,0.484315609,NA,10027457,Metastases to liver,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ondansetron,DB00904
,397324,DB00836,10017885,41,5494,13,4062,0.005672609,2.331591212,1.222853393,4.748621173,0.02262416,DB0083610017885_,3.788736899,0.846550958,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,397468,DB01136,10074903,54,9830,54,11061,0.562913212,1.125221655,0.756390099,1.67390469,0.71505008,DB0113610074903_,0.335402697,0.117980043,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,397485,DB00433,10049848,31,7625,41,5979,0.031681909,0.592912534,0.359026797,0.970102093,0.088398597,DB0043310049848_,2.425899184,-0.522708388,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,prochlorperazine,DB00433
,397536,DB00186,10039117,33,16868,25,9983,0.345115844,0.781237864,0.4503291,1.371245181,0.514527096,DB0018610039117_,0.66450706,-0.246875612,NA,10039117,Rib fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,397880,DB00650,10001760,45,2086,18,1996,0.001371297,2.391839151,1.351711598,4.405707516,0.007143192,DB0065010001760_,4.941595574,0.872062589,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,leucovorin,DB00650
,397886,DB00904,10061520,42,23027,19,14437,0.292086665,1.385898965,0.788128613,2.524277264,0.457552251,DB0090410061520_,0.78186419,0.326349001,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,397887,DB01234,10061520,32,31593,24,32864,0.231828725,1.386960258,0.791473102,2.461363928,0.388116177,DB0123410061520_,0.946450559,0.327114488,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,398201,DB01137,10017944,38,7734,31,5562,0.625805266,0.881563788,0.53341477,1.467200281,0.765350305,DB0113710017944_,0.267421635,-0.126057917,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,levofloxacin,DB01137
,398694,DB01101,10013911,42,7547,16,3892,0.333312061,1.353695799,0.744130062,2.582716239,0.502357082,DB0110110013911_,0.688444093,0.302838481,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,capecitabine,DB01101
,398831,DB01076,10037162,92,25655,60,25523,0.011614445,1.525423452,1.089522192,2.149488956,0.040121656,DB0107610037162_,3.215839045,0.422272045,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,399086,DB01137,10049848,35,7737,30,5563,0.529105376,0.838862927,0.499638689,1.416338991,0.686385096,DB0113710049848_,0.376316444,-0.175707963,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,399168,DB00999,10022687,37,21393,14,12225,0.243346983,1.510239275,0.797070815,3.025462741,0.40166884,DB0099910022687_,0.91212731,0.412268099,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,399630,DB00377,10016825,52,1067,13,710,0.001083328,2.660426182,1.415622996,5.365996158,0.005884535,DB0037710016825_,5.135427561,0.978486329,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,palonosetron,DB00377
,399631,DB00381,10020765,47,29313,44,22843,0.398766865,0.832417514,0.539729008,1.285969852,0.568631641,DB0038110020765_,0.564522434,-0.183421144,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,399633,DB00904,10020765,38,23031,33,14423,0.18007973,0.721152164,0.44015632,1.187050302,0.323916766,DB0090410020765_,1.12726869,-0.326905118,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,399634,DB01075,10020765,36,19912,18,11079,0.777445288,1.112806145,0.61525487,2.08260185,0.878704395,DB0107510020765_,0.129306735,0.106884884,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,diphenhydramine,DB01075
,399636,DB00381,10025197,49,29311,35,22852,0.741922983,1.091519511,0.692806911,1.736013204,0.852093841,DB0038110025197_,0.160058616,0.087570773,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,amlodipine,DB00381
,399847,DB00635,10067152,38,33015,19,23775,0.226910773,1.440244083,0.8097106,2.645603331,0.38208518,DB0063510067152_,0.96211171,0.364812601,NA,10067152,Oral herpes,10021881,Infections and infestations,Infec,prednisone,DB00635
,399890,DB00515,10021789,42,1828,44,2107,0.663896603,1.100206953,0.699895687,1.727333822,0.795302261,DB0051510021789_,0.229033034,0.095498302,NA,10021789,Infection,10021881,Infections and infestations,Infec,cisplatin,DB00515
,399909,DB01073,10018884,63,1002,116,1534,0.268144417,0.831521958,0.595530298,1.152336799,0.430593885,DB0107310018884_,0.842589896,-0.184497572,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,fludarabine,DB01073
,399994,DB01327,10013710,6,657,46,711,5.03749489132092e-08,0.141305781,0.048997023,0.33467845,9.73607008958605e-07,DB0132710013710_,13.8422581,-1.956829076,male,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,cefazolin,DB01327
,400103,DB00776,10070863,91,1814,38,1301,0.005996041,1.717227045,1.155306405,2.596062985,0.02365035,DB0077610070863_,3.744377372,0.540710807,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,oxcarbazepine,DB00776
,400116,DB00190,10011224,40,3257,34,4640,0.032195221,1.675874345,1.031867134,2.736246708,0.089520868,DB0019010011224_,2.41328352,0.516335026,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carbidopa,DB00190
,400350,DB00586,10061428,80,7029,38,2767,0.355103356,0.828788778,0.555030449,1.25694455,0.524891985,DB0058610061428_,0.644562781,-0.187789948,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,diclofenac,DB00586
,400523,DB08890,10046571,49,1898,14,545,1,1.00500359,0.541022471,1.98662305,1,DB0889010046571_,0,0.004991113,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,linaclotide,DB08890
,400629,DB06605,10061024,148,13925,157,12876,0.249116225,0.87166673,0.690678283,1.099610985,0.40850599,DB0660510061024_,0.895248702,-0.137348118,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,apixaban,DB06605
,400656,DB01098,10049848,59,8090,40,7169,0.225261846,1.30705492,0.859077946,2.007002485,0.380136596,DB0109810049848_,0.967224628,0.267776453,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,rosuvastatin,DB01098
,400743,DB00373,10025482,38,1794,16,1271,0.093985892,1.682353802,0.911267373,3.246752272,0.20173002,DB0037310025482_,1.600825009,0.520193886,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,timolol,DB00373
,400842,DB01136,10016825,38,9846,33,11082,0.285933043,1.29604658,0.790789886,2.134145772,0.450611549,DB0113610016825_,0.79714962,0.259318539,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,carvedilol,DB01136
,400845,DB01285,10017577,40,1236,13,596,0.237114755,1.483405845,0.77017779,3.046692172,0.394465908,DB0128510017577_,0.93022256,0.39434069,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,corticotropin,DB01285
,400942,DB00285,10062355,49,10902,22,3696,0.275164529,0.755106358,0.447313351,1.31338095,0.43846891,DB0028510062355_,0.824466371,-0.280896668,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,400944,DB06637,10053762,85,6077,25,1994,0.738367253,1.11560054,0.704772196,1.824662272,0.849356322,DB0663710053762_,0.163276485,0.109392861,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,dalfampridine,DB06637
,400960,DB00381,10022972,34,29326,20,22867,0.339572568,1.325569617,0.741228068,2.431007568,0.508642862,DB0038110022972_,0.676009155,0.281842266,NA,10022972,Iron deficiency anaemia,10005329,Blood and lymphatic system disorders,Blood,amlodipine,DB00381
,400976,DB08932,10054112,1586,17857,517,6080,0.41770033,1.044476351,0.941077024,1.160630212,0.586748079,DB0893210054112_,0.533159718,0.043515661,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,401036,DB00121,10017577,65,4158,10,458,0.32889235,0.716030291,0.362294189,1.574200795,0.497509034,DB0012110017577_,0.698141563,-0.334032808,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,biotin,DB00121
,401147,DB00190,10053762,85,3212,105,4569,0.371026963,1.151505958,0.85158462,1.553341917,0.540676021,DB0019010053762_,0.614935032,0.141070614,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,carbidopa,DB00190
,401183,DB00996,10000496,41,38912,27,22398,0.615025203,0.874075418,0.52474893,1.478012826,0.756478122,DB0099610000496_,0.279081666,-0.134588616,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,gabapentin,DB00996
,401232,DB00557,10022095,64,5923,23,3044,0.171518927,1.4300095,0.873650842,2.41881642,0.312823575,DB0055710022095_,1.162115907,0.357681088,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,401302,DB01142,10046735,40,1700,10,774,0.091592214,1.820795355,0.888997828,4.104878063,0.197814498,DB0114210046735_,1.620425566,0.599273414,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,doxepin,DB01142
,401368,DB00811,10047513,37,2761,34,4122,0.05087684,1.62450287,0.989277127,2.675247613,0.12665177,DB0081110047513_,2.066313924,0.485201843,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ribavirin,DB00811
,401434,DB00706,10076309,11,1064,91,15834,0.096931679,1.798789874,0.86468781,3.386067728,0.206153345,DB0070610076309_,1.579134995,0.587114146,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tamsulosin,DB00706
,401450,DB08895,10003983,54,28060,11,6635,0.753398965,1.160786368,0.599701988,2.463350782,0.861266116,DB0889510003983_,0.149351745,0.149097679,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,401572,DB00678,10005746,36,15563,16,10708,0.159012851,1.548068577,0.836965668,2.989514462,0.296187704,DB0067810005746_,1.21676189,0.437008075,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,losartan,DB00678
,401631,DB01060,10015090,36,8551,23,5058,0.788082374,0.925847623,0.533126745,1.638493989,0.885191486,DB0106010015090_,0.121951289,-0.077045612,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amoxicillin,DB01060
,401835,DB00213,10005802,31,18864,19,13402,0.6682405,1.159125815,0.634173417,2.172700091,0.798462803,DB0021310005802_,0.225066897,0.147666114,NA,10005802,Blood sodium decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,401847,DB00327,10013663,58,6080,50,4212,0.279633441,0.803629143,0.539806791,1.200084504,0.443462186,DB0032710013663_,0.813142743,-0.218617381,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,hydromorphone,DB00327
,401855,DB00996,10013663,82,38871,57,22368,0.290187727,0.827840446,0.583005557,1.182480261,0.455364581,DB0099610013663_,0.786656905,-0.188934841,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,401983,DB08889,10017577,36,3129,25,3860,0.028061569,1.776242209,1.034713511,3.094389116,0.080365913,DB0888910017577_,2.52116516,0.574500014,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,402085,DB00203,10052904,34,13844,28,8910,0.362540598,0.781533669,0.459619599,1.338938828,0.53220405,DB0020310052904_,0.63072831,-0.246497048,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,402086,DB08932,10052904,46,19397,14,6583,0.881847197,1.115107786,0.601869069,2.197979934,0.950577357,DB0893210052904_,0.050685735,0.108951069,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,402249,DB00423,10041349,45,2422,14,1026,0.388541822,1.361457577,0.729984598,2.698235762,0.558520236,DB0042310041349_,0.582464428,0.308555874,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,methocarbamol,DB00423
,402556,DB01137,10043239,50,7722,29,5564,0.363336311,1.242287818,0.76991304,2.038686752,0.532861533,DB0113710043239_,0.629493677,0.216954694,NA,10043239,Tendon disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,levofloxacin,DB01137
,402775,DB08906,10016322,46,2147,11,1147,0.016184084,2.23360733,1.134135033,4.801697265,0.052295612,DB0890610016322_,2.950842814,0.803617915,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,fluticasone furoate,DB08906
,402791,DB00814,10013754,34,8253,19,3396,0.290830729,0.736359003,0.40761415,1.368640685,0.456142115,DB0081410013754_,0.784950863,-0.306037503,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,403003,DB06605,10003662,56,14017,54,12979,0.848835212,0.960229277,0.648304289,1.423385518,0.924662076,DB0660510003662_,0.078326932,-0.040583193,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,apixaban,DB06605
,403006,DB06605,10013971,212,13861,121,12912,1.55605905907696e-05,1.632073762,1.297573714,2.060463885,0.000159894,DB0660510013971_,8.740996353,0.489851453,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,403028,DB01275,10000087,29,3950,35,3314,0.165912367,0.695202452,0.408950655,1.173535017,0.305339161,DB0127510000087_,1.186332116,-0.363552179,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,hydralazine,DB01275
,403067,DB00273,10020642,59,8422,14,2179,0.884718026,1.090334701,0.600036611,2.118902535,0.951954206,DB0027310020642_,0.049238348,0.086484714,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,topiramate,DB00273
,403076,DB06700,10044565,53,2172,9,609,0.211862081,1.650874328,0.801372766,3.82932738,0.363628901,DB0670010044565_,1.011621433,0.501305044,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,desvenlafaxine,DB06700
,403088,DB00627,10069339,12,1317,40,1559,0.001066208,0.355252234,0.168896013,0.694183609,0.00580654,DB0062710069339_,5.148770391,-1.034927224,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,niacin,DB00627
,403106,DB01202,10020751,51,6663,25,5693,0.027628689,1.742936755,1.058625278,2.939613036,0.079416052,DB0120210020751_,2.533054765,0.555571481,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,levetiracetam,DB01202
,403282,DB01046,10016173,39,846,14,314,1,1.033939615,0.540348736,2.090973615,1,DB0104610016173_,0,0.033376375,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,lubiprostone,DB01046
,403341,DB01109,10029331,44,4368,10,4260,3.66863764256863e-06,4.290367745,2.124040616,9.572324619,4.50397666674061e-05,DB0110910029331_,10.00796475,1.456372451,female,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,heparin,DB01109
,403405,DB00186,10067482,53,16848,23,9985,0.235524421,1.365660933,0.822044603,2.33622682,0.392656896,DB0018610067482_,0.934819086,0.311638511,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,403471,DB00285,10019063,65,10886,33,3685,0.062336471,0.666778939,0.431309406,1.048579325,0.147806968,DB0028510019063_,1.911848125,-0.405296713,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,venlafaxine,DB00285
,403511,DB09037,10008479,19,2507,32,2803,0.161894051,0.663905457,0.354586566,1.21099082,0.29993904,DB0903710008479_,1.204176025,-0.409615523,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,pembrolizumab,DB09037
,403513,DB06262,10012735,80,3720,75,4239,0.255208681,1.215451105,0.872955225,1.693837402,0.415906763,DB0626210012735_,0.877294171,0.195115288,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,droxidopa,DB06262
,403525,DB00285,10022000,90,10861,11,3707,0.000491417,2.792565902,1.486438895,5.799395427,0.003050398,DB0028510022000_,5.792483346,1.026960851,female,10022000,Influenza,10021881,Infections and infestations,Infec,venlafaxine,DB00285
,403573,DB00904,10062501,37,23032,14,14442,0.114297091,1.657156333,0.87466541,3.319369059,0.232576365,DB0090410062501_,1.458536656,0.505103081,NA,10062501,Non-cardiac chest pain,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,403824,DB00996,10056819,93,38860,50,22375,0.728703665,1.070965447,0.751205268,1.542648375,0.841846954,DB0099610056819_,0.172157046,0.068560529,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,403825,DB01068,10056819,40,13723,14,6826,0.311442128,1.421157506,0.756316582,2.830097061,0.478940472,DB0106810056819_,0.736178966,0.351471685,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,clonazepam,DB01068
,403885,DB00829,10022000,57,7995,20,4434,0.093961343,1.580546295,0.933753963,2.781361893,0.20169652,DB0082910022000_,1.600991086,0.457770543,NA,10022000,Influenza,10021881,Infections and infestations,Infec,diazepam,DB00829
,404048,DB01048,10071404,33,432,59,1076,0.15551623,1.392825896,0.867711803,2.203449626,0.291492432,DB0104810071404_,1.232741237,0.331334702,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,abacavir,DB01048
,404092,DB00734,10008479,32,4018,20,4882,0.024450317,1.943882295,1.076272573,3.592307217,0.072298412,DB0073410008479_,2.626953115,0.664687156,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,risperidone,DB00734
,404110,DB00455,10021143,50,9351,35,5083,0.256333525,0.776573262,0.493486707,1.2342164,0.41717087,DB0045510021143_,0.874259382,-0.252864292,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loratadine,DB00455
,404124,DB00814,10062355,47,8240,14,3401,0.324604014,1.385547411,0.748745815,2.728924255,0.493091948,DB0081410062355_,0.707059616,0.326095304,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,404194,DB00836,10013971,45,5490,25,4050,0.276388918,1.327829606,0.795511129,2.26355769,0.439829436,DB0083610013971_,0.821368274,0.283545734,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loperamide,DB00836
,404195,DB01592,10013971,59,6217,16,3051,0.035474414,1.809542463,1.025558897,3.375204999,0.096436547,DB0159210013971_,2.338870035,0.593074031,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iron,DB01592
,404243,DB01590,10061822,34,4704,17,2850,0.564681026,1.211665077,0.657009216,2.317299673,0.716402216,DB0159010061822_,0.333513516,0.19199551,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,everolimus,DB01590
,404294,DB00904,10012373,42,23027,17,14439,0.141380736,1.549155703,0.862791606,2.903820621,0.271780645,DB0090410012373_,1.30275999,0.437710075,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,404380,DB01062,10000059,40,4446,17,1728,0.767586562,0.914521231,0.505228243,1.725316062,0.872363057,DB0106210000059_,0.136549592,-0.089354595,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,oxybutynin,DB01062
,404383,DB01136,10001949,34,9850,37,11078,0.905719295,1.033489754,0.628740478,1.694033635,0.957861963,DB0113610001949_,0.0430516,0.032941186,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,carvedilol,DB01136
,404387,DB01136,10017944,38,9846,28,11087,0.107722641,1.528153821,0.912714646,2.587412636,0.222691978,DB0113610017944_,1.501965727,0.424060354,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,carvedilol,DB01136
,404488,DB08932,10041101,38,19405,15,6582,0.635712873,0.859311422,0.461400111,1.682710195,0.77357991,DB0893210041101_,0.256726304,-0.151623883,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,404501,DB01202,10039020,17,6697,111,5607,6.5164765635746e-22,0.128247775,0.072036594,0.215090425,8.21513604189729e-20,DB0120210039020_,43.94572355,-2.053791144,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,levetiracetam,DB01202
,404528,DB00761,10019641,27,15280,35,8590,0.001283685,0.433687517,0.252281267,0.738019763,0.006755764,DB0076110019641_,4.997359263,-0.835431011,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,potassium chloride,DB00761
,404530,DB00028,10030124,46,13412,27,5588,0.158503802,0.709847863,0.431574999,1.188763923,0.295501271,DB0002810030124_,1.21908214,-0.34270461,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,404562,DB01109,10018964,25,4387,32,4238,0.352309665,0.75474286,0.4280186,1.316916132,0.522058678,DB0110910018964_,0.649975288,-0.28137817,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,heparin,DB01109
,404655,DB01202,10030124,38,6676,21,5697,0.117136801,1.544110158,0.88231109,2.772885338,0.236850711,DB0120210030124_,1.440325248,0.434447795,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,404677,DB00047,10022095,35,9250,19,8499,0.075473393,1.692490586,0.941161751,3.13474213,0.170592325,DB0004710022095_,1.768478636,0.526201164,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,404739,DB01413,10002034,41,1179,19,1640,5.39683755838487e-05,3.000517481,1.692469224,5.503145173,0.000470969,DB0141310002034_,7.660718196,1.098784767,female,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,cefepime,DB01413
,404757,DB08931,10007554,111,6466,34,2412,0.347104096,1.217791398,0.820059863,1.850378276,0.516524538,DB0893110007554_,0.660632484,0.197038889,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,riociguat,DB08931
,404759,DB08820,10013968,164,4237,121,3424,0.467073498,1.095324116,0.856807049,1.403249788,0.633603947,DB0882010013968_,0.456331209,0.091050315,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ivacaftor,DB08820
,404778,DB01015,10025256,31,9856,19,9362,0.156364091,1.549759838,0.847585872,2.905695829,0.292518425,DB0101510025256_,1.229227624,0.438099975,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,404942,DB01190,10042674,47,4887,14,2271,0.167007709,1.559984052,0.842234788,3.074740081,0.306817936,DB0119010042674_,1.181500749,0.444675598,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,clindamycin,DB01190
,404960,DB00476,10022081,48,17209,8,6169,0.047051523,2.15087577,1.007845926,5.267305991,0.119544659,DB0047610022081_,2.124065258,0.765875094,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,405043,DB00153,10036790,37,7386,16,3423,0.883218532,1.071707299,0.580747147,2.066566917,0.951169726,DB0015310036790_,0.050062761,0.069252983,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,405097,DB05676,10040984,58,47071,28,25301,0.734463921,1.113400105,0.69747287,1.816292984,0.846366607,DB0567610040984_,0.166802671,0.107418491,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,405202,DB05676,10018627,31,47098,58,25271,8.7232089277566e-09,0.286788418,0.179136516,0.451120893,1.98777240282689e-07,DB0567610018627_,15.43108103,-1.249010555,male,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,apremilast,DB05676
,405205,DB00433,10061623,69,7587,59,5961,0.65528887,0.918859373,0.638516072,1.325890231,0.788963159,DB0043310061623_,0.237035652,-0.08462219,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,prochlorperazine,DB00433
,405219,DB06403,10035528,58,21413,22,6639,0.429693874,0.817388085,0.492251621,1.403750321,0.598194136,DB0640310035528_,0.513839936,-0.201641284,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,ambrisentan,DB06403
,405259,DB08932,10059864,36,19407,15,6582,0.519612328,0.813964019,0.434333157,1.601333152,0.678760066,DB0893210059864_,0.387487577,-0.205839117,NA,10059864,Cardiac ablation,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,405371,DB00989,10041349,17,817,45,833,0.000667554,0.385361395,0.205002119,0.693396337,0.003940414,DB0098910041349_,5.536469488,-0.953573697,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,rivastigmine,DB00989
,405412,DB00437,10017944,27,6894,40,11506,0.616049322,1.126555568,0.664202361,1.883691632,0.757259402,DB0043710017944_,0.278049413,0.119164808,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,allopurinol,DB00437
,405489,DB00230,10038669,47,19627,15,8636,0.33423284,1.378724069,0.756945331,2.656157336,0.503340793,DB0023010038669_,0.686487818,0.321158484,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pregabalin,DB00230
,405516,DB00343,10065154,40,8696,17,5078,0.335507905,1.373961836,0.760515977,2.587523819,0.50470973,DB0034310065154_,0.683771807,0.317698417,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,diltiazem,DB00343
,405544,DB01065,10007515,37,4294,33,3018,0.331243951,0.788067328,0.478269276,1.303533333,0.499991129,DB0106510007515_,0.693164923,-0.238171751,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,melatonin,DB01065
,405674,DB00005,10012434,51,128031,8,42411,0.049236466,2.111614076,0.994691436,5.152897629,0.123555348,DB0000510012434_,2.091066058,0.74745262,NA,10012434,Dermatitis allergic,10040785,Skin and subcutaneous tissue disorders,Skin,etanercept,DB00005
,405697,DB01142,10007515,45,1695,25,759,0.431956706,0.806112945,0.479796779,1.382515467,0.600431933,DB0114210007515_,0.510105994,-0.215531416,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,doxepin,DB01142
,405698,DB01142,10038669,35,1705,22,762,0.246292138,0.711100229,0.402534102,1.281721272,0.405284923,DB0114210038669_,0.903164946,-0.34094189,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,doxepin,DB01142
,405699,DB00669,10005750,47,6330,12,1085,0.264549519,0.671383046,0.349265314,1.395110702,0.426508868,DB0066910005750_,0.85212212,-0.398415446,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,sumatriptan,DB00669
,405765,DB11750,10012378,57,2443,13,1500,0.00068219,2.69156852,1.449611653,5.378134718,0.004005665,DB1175010012378_,5.520045764,0.990124117,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,clobetasol,DB11750
,405797,DB00423,10010144,90,2377,13,1027,6.39857926201234e-05,2.990440001,1.653854497,5.8597942,0.00054359,DB0042310010144_,7.517315807,1.095420534,female,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,methocarbamol,DB00423
,405798,DB00175,10033295,27,8104,37,6069,0.021941497,0.546521235,0.319666511,0.92331066,0.066502912,DB0017510033295_,2.71050955,-0.604182116,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,405890,DB00158,10036790,62,16753,33,8071,0.66123932,0.905140363,0.583598596,1.426999177,0.793354286,DB0015810036790_,0.23148539,-0.09966525,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,folic acid,DB00158
,405900,DB00338,10061598,36,33638,16,22256,0.203740789,1.488662441,0.805085591,2.873961325,0.35352191,DB0033810061598_,1.039809816,0.397878026,NA,10061598,Immunodeficiency,10021428,Immune system disorders,Immun,omeprazole,DB00338
,405924,DB00285,10013781,63,10888,22,3696,0.900744342,0.972079894,0.588972733,1.661576677,0.956763316,DB0028510013781_,0.044199237,-0.028317283,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,406258,DB06228,10010144,114,15798,97,15979,0.214578708,1.188714869,0.897934974,1.576264023,0.366985578,DB0622810010144_,1.002432729,0.172872781,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,rivaroxaban,DB06228
,406518,DB01181,10065553,33,540,27,893,0.009521462,2.020237436,1.163634698,3.53476893,0.034234545,DB0118110065553_,3.374520055,0.703215047,NA,10065553,Bone marrow failure,10005329,Blood and lymphatic system disorders,Blood,ifosfamide,DB01181
,407029,DB01060,10022004,34,8553,26,5055,0.349404155,0.772903292,0.449677506,1.342913004,0.519006991,DB0106010022004_,0.655837925,-0.257601345,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,407216,DB01067,10064848,38,4323,28,4795,0.108358336,1.50524092,0.898058669,2.551253922,0.223571127,DB0106710064848_,1.498025674,0.408952965,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,glipizide,DB01067
,407541,DB00213,10052015,27,18868,44,13377,0.000638513,0.435062686,0.258911859,0.71877422,0.003795842,DB0021310052015_,5.573849033,-0.832265153,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,pantoprazole,DB00213
,407545,DB00497,10052015,25,19242,45,16330,0.002481731,0.471486444,0.276946932,0.7858921,0.011599948,DB0049710052015_,4.456754638,-0.751864929,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,oxycodone,DB00497
,407547,DB00787,10052015,59,16941,113,17135,6.23595954711509e-05,0.528115595,0.378503697,0.730362572,0.000532467,DB0078710052015_,7.537990468,-0.63844009,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,acyclovir,DB00787
,407552,DB11089,10052015,26,10149,31,8376,0.183266978,0.692210668,0.394405818,1.205735202,0.327966539,DB1108910052015_,1.11484369,-0.367864936,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,docusate,DB11089
,407607,DB08935,10008531,21,511,77,736,9.88929682235556e-05,0.393061635,0.227281131,0.653552529,0.000789492,DB0893510008531_,7.144121142,-0.933788847,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,obinutuzumab,DB08935
,408385,DB08932,10064355,75,19368,17,6580,0.149456349,1.49877109,0.875896458,2.709581987,0.283234328,DB0893210064355_,1.261480709,0.404645499,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,408487,DB01275,10016322,57,3922,27,3322,0.014899271,1.78800609,1.109583003,2.94752121,0.049051519,DB0127510016322_,3.014884116,0.581101083,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,hydralazine,DB01275
,408643,DB00316,10029446,35,65439,35,36918,0.017799929,0.564191672,0.342818381,0.928410135,0.056383603,DB0031610029446_,2.875576893,-0.572361241,NA,10029446,Nocturia,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,408645,DB00381,10029446,31,29329,38,22849,0.068238067,0.635563313,0.382240256,1.049315148,0.158113327,DB0038110029446_,1.844443244,-0.453243566,NA,10029446,Nocturia,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,408750,DB09027,10010774,94,5085,129,7023,1,1.006398354,0.761222131,1.326495064,1,DB0902710010774_,0,0.006377972,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ledipasvir,DB09027
,408795,DB00028,10064306,35,13423,15,5600,1,0.97345407,0.517552271,1.920118248,1,DB0002810064306_,0,-0.026904635,NA,10064306,Incorrect drug administration rate,10022117,"Injury, poisoning and procedural complications",Inj&P,human immunoglobulin g,DB00028
,408880,DB00198,10035664,83,1192,79,924,0.218548175,0.814495204,0.583879842,1.1368545,0.371730597,DB0019810035664_,0.989585889,-0.205186739,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,oseltamivir,DB00198
,409002,DB11093,10010264,42,1615,10,650,0.161999093,1.690063023,0.828209608,3.801216024,0.300044182,DB1109310010264_,1.203825541,0.52476582,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,calcium citrate,DB11093
,409079,DB00343,10019304,38,8698,17,5078,0.402868285,1.304968128,0.718077861,2.468277598,0.572631762,DB0034310019304_,0.557512417,0.266178618,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,diltiazem,DB00343
,409159,DB00972,10028334,42,2462,14,1165,0.312629377,1.419459628,0.756273709,2.825907961,0.480118208,DB0097210028334_,0.73372294,0.350276256,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,azelastine,DB00972
,409614,DB00158,10024384,42,16773,15,8089,0.395725877,1.350358288,0.733100541,2.623019845,0.565399504,DB0015810024384_,0.570222711,0.300369956,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,folic acid,DB00158
,410079,DB01275,10010144,52,3927,63,3286,0.058738608,0.690710394,0.467574448,1.016478808,0.141141267,DB0127510010144_,1.957993995,-0.370034654,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,hydralazine,DB01275
,410130,DB14500,10038428,42,7767,18,4055,0.585720548,1.218136767,0.685155787,2.25133612,0.733075487,DB1450010038428_,0.310506599,0.197322451,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,potassium,DB14500
,410373,DB14513,10029354,47,7130,35,3529,0.07695697,0.664658402,0.419189813,1.062900903,0.17308803,DB1451310029354_,1.753954968,-0.408482052,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,magnesium,DB14513
,410619,DB00188,10044034,37,7849,36,8792,0.559100178,1.151246648,0.706902771,1.876526639,0.711840552,DB0018810044034_,0.339901337,0.140845397,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,bortezomib,DB00188
,410638,DB11089,10044034,33,10142,25,8382,0.792531407,1.090958898,0.628703324,1.915217526,0.887531177,DB1108910044034_,0.119311629,0.087057032,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,411105,DB06262,10027599,81,3719,16,4298,1.10839004376078e-13,5.849154303,3.386227409,10.73741098,5.62976469570091e-12,DB0626210027599_,25.90295347,1.766297087,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,411368,DB06674,10022000,53,4453,6,1484,0.00623204,2.943532933,1.262753635,8.396692857,0.024394514,DB0667410022000_,3.713397007,1.079610538,female,10022000,Influenza,10021881,Infections and infestations,Infec,golimumab,DB06674
,411384,DB00065,10031161,45,9419,14,4943,0.098938699,1.686769941,0.908151182,3.330611541,0.209263173,DB0006510031161_,1.564162616,0.522815423,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,infliximab,DB00065
,411988,DB00193,10042464,65,19255,19,8683,0.099173908,1.542694303,0.912923793,2.726150175,0.209590847,DB0019310042464_,1.562597994,0.433530435,NA,10042464,Suicide attempt,10037175,Psychiatric disorders,Psych,tramadol,DB00193
,412089,DB01137,10047513,35,7737,26,5567,0.897319728,0.968584492,0.565858567,1.677681044,0.956338178,DB0113710047513_,0.044643686,-0.03191956,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,levofloxacin,DB01137
,412100,DB00028,10019974,63,13395,19,5596,0.226979464,1.38515324,0.817450345,2.453098155,0.382127407,DB0002810019974_,0.962001199,0.325810776,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,412187,DB01050,10014387,50,18058,30,9341,0.555171767,0.862141661,0.537200018,1.405341186,0.708658212,DB0105010014387_,0.344381939,-0.148335682,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,ibuprofen,DB01050
,412341,DB00956,10064848,52,5762,31,3436,1,1.000259891,0.627795493,1.618059691,1,DB0095610064848_,0,0.000259857,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,hydrocodone,DB00956
,412425,DB00758,10010144,38,8262,69,10005,0.050975789,0.666924494,0.436120752,1.006168361,0.126848301,DB0075810010144_,2.064763383,-0.405078442,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,clopidogrel,DB00758
,412462,DB09033,10046735,41,2583,18,1651,0.226005793,1.455786404,0.814608724,2.701850651,0.38089073,DB0903310046735_,0.965242744,0.375546238,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,vedolizumab,DB09033
,412466,DB00635,10006825,34,33019,16,23778,0.196478799,1.530264837,0.821688982,2.969720295,0.34471889,DB0063510006825_,1.065026007,0.425440816,NA,10006825,C-reactive protein increased,10022891,Investigations,Inv,prednisone,DB00635
,412484,DB00993,10040753,41,3208,11,1608,0.074950405,1.868071257,0.939903708,4.040626751,0.169782514,DB0099310040753_,1.773236993,0.624906485,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,azathioprine,DB00993
,412665,DB09033,10011224,40,2584,24,1645,0.897493608,1.061009399,0.621540477,1.847314672,0.956338178,DB0903310011224_,0.044643686,0.059220718,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,vedolizumab,DB09033
,412690,DB00005,10056723,48,128034,9,42410,0.126211102,1.766530612,0.857241902,4.095598995,0.250430952,DB0000510056723_,1.384572038,0.569017517,NA,10056723,Dental care,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,412727,DB09033,10037087,70,2554,25,1644,0.010596366,1.802117436,1.121527638,2.983432306,0.037273399,DB0903310037087_,3.289475372,0.588962327,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,vedolizumab,DB09033
,412769,DB00973,10065154,64,3787,32,2989,0.038127507,1.578454311,1.014191943,2.500968555,0.101852891,DB0097310065154_,2.284225751,0.456446084,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,ezetimibe,DB00973
,413346,DB01015,10005750,38,9849,32,9349,0.633964619,1.127207237,0.685098599,1.865406595,0.772364311,DB0101510005750_,0.258298935,0.119743102,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,413387,DB00531,10039906,65,7187,50,6466,0.453339943,1.169569994,0.795185666,1.729167326,0.620886445,DB0053110039906_,0.476607072,0.156636155,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,413439,DB00761,10016766,64,15243,25,8600,0.122774376,1.444313928,0.89607091,2.395518552,0.245371385,DB0076110016766_,1.404982358,0.367634419,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,413928,DB00814,10038695,20,8267,33,3382,8.10081682200164e-07,0.247971763,0.134636052,0.445885178,1.18988527614592e-05,DB0081410038695_,11.33906857,-1.394440398,male,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,meloxicam,DB00814
,413983,DB01195,10014387,36,1203,19,725,0.674831046,1.141836019,0.632290125,2.124346617,0.80280308,DB0119510014387_,0.219645825,0.13263751,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,flecainide,DB01195
,414401,DB06605,10020772,115,13958,85,12948,0.11836871,1.255029982,0.938962405,1.683088752,0.23877223,DB0660510020772_,1.432245194,0.227159462,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,apixaban,DB06605
,414502,DB00904,10020100,62,23007,29,14427,0.197818712,1.340622183,0.849067804,2.162562333,0.346367229,DB0090410020100_,1.060255713,0.293133822,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,414589,DB00184,10011906,43,1251,45,937,0.125781674,0.715828676,0.455936029,1.122526412,0.249748549,DB0018410011906_,1.387300671,-0.33431442,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,nicotine,DB00184
,414615,DB00787,10073133,47,16953,56,17192,0.431243781,0.851122634,0.564662691,1.277904773,0.599653112,DB0078710073133_,0.511403938,-0.161199054,NA,10073133,Plasma cell myeloma recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acyclovir,DB00787
,414700,DB00210,10054786,150,735,40,309,0.017843821,1.57598909,1.075155114,2.351980858,0.056488598,DB0021010054786_,2.873716468,0.454883069,NA,10054786,Skin burning sensation,10040785,Skin and subcutaneous tissue disorders,Skin,adapalene,DB00210
,414757,DB00480,10023003,71,67357,16,67646,1.11128759612159e-09,4.45625467,2.564206953,8.217080674,3.05705855196818e-08,DB0048010023003_,17.30322755,1.494308653,female,10023003,Irritable bowel syndrome,10017947,Gastrointestinal disorders,Gastr,lenalidomide,DB00480
,414844,DB00567,10006451,57,4462,20,2061,0.325118955,1.316416399,0.776433656,2.319725673,0.493548404,DB0056710006451_,0.706134342,0.274913196,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,cephalexin,DB00567
,414879,DB00476,10043554,45,17212,20,6157,0.400919323,0.804850115,0.465189551,1.440110382,0.570747843,DB0047610043554_,0.560807772,-0.217099211,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,duloxetine,DB00476
,415082,DB00641,10065154,57,14067,52,12423,0.923458688,0.968038325,0.652467144,1.439035097,0.966651863,DB0064110065154_,0.033916866,-0.032483601,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,simvastatin,DB00641
,415127,DB00285,10017955,35,10916,24,3694,0.010095196,0.493511537,0.284917847,0.868449183,0.035848719,DB0028510017955_,3.328447449,-0.706209043,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,venlafaxine,DB00285
,415151,DB06605,10036653,39,14034,30,13003,0.470950087,1.204486752,0.728749902,2.009002588,0.637208683,DB0660510036653_,0.450658075,0.186053544,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,415225,DB00019,10048334,44,18968,19,9510,0.688594574,1.161050864,0.663498368,2.106979068,0.812301786,DB0001910048334_,0.207883351,0.149325512,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,pegfilgrastim,DB00019
,415230,DB00218,10003239,49,1393,20,930,0.079808826,1.635359227,0.947049182,2.924542209,0.17809449,DB0021810003239_,1.725441028,0.491862491,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,moxifloxacin,DB00218
,415237,DB01020,10003239,35,1778,27,1851,0.251886826,1.34940367,0.7898706,2.328513655,0.411949055,DB0102010003239_,0.886855589,0.299662769,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,isosorbide mononitrate,DB01020
,415745,DB08820,10047461,34,4367,24,3521,0.691518883,1.142186736,0.656339476,2.017264185,0.814003975,DB0882010047461_,0.20579003,0.132944614,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,ivacaftor,DB08820
,415752,DB01195,10013710,45,1194,14,730,0.028569044,1.96457536,1.050074209,3.904007511,0.081534996,DB0119510013710_,2.506722953,0.67527612,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,flecainide,DB01195
,415777,DB00051,10042868,65,25666,12,11408,0.00288285,2.407548019,1.288339675,4.899188444,0.013087341,DB0005110042868_,4.336109829,0.87860881,NA,10042868,Synovitis,10028395,Musculoskeletal and connective tissue disorders,Musc,adalimumab,DB00051
,416290,DB00490,10028810,46,4024,18,1558,1,0.989453875,0.560633048,1.819023632,1,DB0049010028810_,0,-0.010602129,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,buspirone,DB00490
,416291,DB00586,10028810,104,7005,26,2779,0.039044164,1.586837254,1.021734158,2.547645406,0.10374282,DB0058610028810_,2.26584033,0.461742887,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,diclofenac,DB00586
,416387,DB00586,10064848,52,7057,21,2784,0.896929356,0.976863482,0.577024415,1.710665629,0.956338178,DB0058610064848_,0.044643686,-0.023408368,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,diclofenac,DB00586
,416569,DB01175,10013654,38,10686,14,4878,0.551691263,1.238990216,0.655501971,2.477967685,0.7056204,DB0117510013654_,0.348677864,0.214296706,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,escitalopram,DB01175
,416648,DB06262,10061623,62,3738,44,4270,0.018362764,1.609524089,1.073325591,2.431643655,0.057766173,DB0626210061623_,2.851351921,0.475938538,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,416662,DB00987,10017533,31,2073,22,2906,0.016716277,1.975069348,1.103725124,3.591216493,0.053668908,DB0098710017533_,2.924921445,0.680603511,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,cytarabine,DB00987
,416727,DB00091,10052904,48,5462,6,2664,0.000377783,3.901068318,1.6643336,11.1700282,0.002446725,DB0009110052904_,6.013005043,1.361250443,female,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclosporine,DB00091
,417035,DB00972,10028810,48,2456,12,1167,0.050157387,1.900360914,0.98973636,3.946145659,0.125320566,DB0097210028810_,2.0768803,0.642043823,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,azelastine,DB00972
,417150,DB00264,10073085,47,29560,43,24849,0.750946759,0.91882911,0.594325486,1.423716112,0.859247587,DB0026410073085_,0.151698172,-0.084655127,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,417152,DB00695,10073085,45,28004,41,20487,0.326439017,0.802956348,0.513899676,1.257685196,0.494974631,DB0069510073085_,0.703248768,-0.219454928,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,417153,DB06228,10073085,30,15882,35,16041,0.620088157,0.865728564,0.51314891,1.452273208,0.760641086,DB0622810073085_,0.273593667,-0.144183856,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,418066,DB00829,10037153,44,8008,16,4438,0.176414814,1.523990237,0.841963015,2.896909453,0.319225072,DB0082910037153_,1.141858871,0.421332051,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,diazepam,DB00829
,418702,DB00788,10029148,42,9314,22,5039,1,1.032843041,0.601938496,1.818832066,1,DB0078810029148_,0,0.032315234,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,naproxen,DB00788
,418731,DB00273,10069339,44,8437,17,2176,0.154493643,0.667564764,0.372952809,1.248818352,0.290100965,DB0027310069339_,1.237526263,-0.404118869,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,topiramate,DB00273
,418894,DB11065,10012735,218,2968,151,2537,0.058800197,1.234014259,0.991161862,1.539453633,0.141228878,DB1106510012735_,1.957373456,0.21027248,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pancrelipase amylase,DB11065
,418902,DB11065,10033645,50,3136,34,2654,0.377775572,1.244513263,0.786463181,1.990751955,0.547720732,DB1106510033645_,0.601989736,0.2187445,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,pancrelipase amylase,DB11065
,419048,DB00433,10022000,78,7578,63,5957,0.932087918,0.973248546,0.688053094,1.381325392,0.972972376,DB0043310022000_,0.027399587,-0.027115786,NA,10022000,Influenza,10021881,Infections and infestations,Infec,prochlorperazine,DB00433
,419172,DB00760,10070863,32,748,42,973,1,0.991091946,0.59923147,1.625358452,1,DB0076010070863_,0,-0.008947967,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,meropenem,DB00760
,419266,DB05679,10015150,38,6893,18,4891,0.174959261,1.497910466,0.833013838,2.791730832,0.317399695,DB0567910015150_,1.147593431,0.404071114,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,ustekinumab,DB05679
,419388,DB00864,10028116,30,6839,57,8335,0.051728061,0.641464473,0.397455116,1.01642444,0.128287338,DB0086410028116_,2.053482702,-0.444001478,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,419395,DB01073,10066262,31,1034,19,1631,0.001156343,2.572688008,1.39970027,4.847290558,0.006211192,DB0107310066262_,5.081402404,0.94495127,NA,10066262,Acute graft versus host disease in skin,10021428,Immune system disorders,Immun,fludarabine,DB01073
,419536,DB01076,10061148,33,25714,19,25564,0.070326765,1.726682023,0.953183531,3.215007627,0.161861478,DB0107610061148_,1.821014383,0.546201661,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,419588,DB00646,10006451,41,3412,13,1987,0.064252368,1.836475454,0.961853079,3.744682254,0.151075543,DB0064610006451_,1.889975285,0.607848221,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,nystatin,DB00646
,419842,DB00222,10035226,17,3189,33,3095,0.022356925,0.500022997,0.260639076,0.9260909,0.067429921,DB0022210035226_,2.696666428,-0.693101187,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,glimepiride,DB00222
,419868,DB00190,10030124,51,3246,51,4623,0.085127966,1.424123574,0.94420832,2.148044842,0.186980449,DB0019010030124_,1.676751218,0.353556589,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,420066,DB00341,10054112,117,11288,46,5022,0.550526825,1.131573195,0.796663799,1.630959652,0.704654224,DB0034110054112_,0.350048059,0.123608872,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,cetirizine,DB00341
,420197,DB06262,10064355,59,3741,54,4260,0.255948998,1.244133198,0.843059964,1.839263306,0.416728011,DB0626210064355_,0.875321523,0.218439061,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,droxidopa,DB06262
,420321,DB00028,10034839,37,13421,18,5597,0.656741604,0.857256124,0.47536554,1.601018847,0.79011594,DB0002810034839_,0.235575585,-0.154018544,NA,10034839,Pharyngitis streptococcal,10021881,Infections and infestations,Infec,human immunoglobulin g,DB00028
,420323,DB00451,10034839,43,47228,11,15408,0.530663521,1.275315671,0.646521598,2.743022041,0.687659764,DB0045110034839_,0.374461092,0.243193733,NA,10034839,Pharyngitis streptococcal,10021881,Infections and infestations,Infec,levothyroxine,DB00451
,420473,DB08931,10040753,114,6463,21,2425,0.001722037,2.036743675,1.267498576,3.424743995,0.008594652,DB0893110040753_,4.756615136,0.711352295,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,riociguat,DB08931
,420476,DB08931,10053483,100,6477,21,2425,0.013452057,1.782804806,1.102525626,3.013001488,0.045077425,DB0893110053483_,3.099373721,0.578187858,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,420489,DB00480,10015915,34,67394,22,67640,0.110499819,1.551081894,0.881162635,2.784136691,0.226806789,DB0048010015915_,1.483656773,0.438952684,NA,10015915,Eye discharge,10015919,Eye disorders,Eye,lenalidomide,DB00480
,420767,DB00051,10013745,39,25692,26,11394,0.107919496,0.66523369,0.394602172,1.138742562,0.22295524,DB0005110013745_,1.500784244,-0.407616886,NA,10013745,Drug specific antibody present,10022891,Investigations,Inv,adalimumab,DB00051
,420849,DB08904,10033775,85,11525,15,3544,0.044354372,1.742417166,0.997704189,3.253572324,0.11430508,DB0890410033775_,2.168884268,0.555273325,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,certolizumab pegol,DB08904
,420962,DB01015,10023547,41,9846,53,9328,0.147815941,0.732901741,0.474835325,1.12406741,0.28094595,DB0101510023547_,1.269592976,-0.310743637,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,421151,DB00455,10017413,48,9353,33,5085,0.296447205,0.790831029,0.496534567,1.273464851,0.462330294,DB0045510017413_,0.771475721,-0.234670951,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,loratadine,DB00455
,421388,DB08889,10008531,27,3138,38,3847,0.618113399,0.871087329,0.510240469,1.46832008,0.759051167,DB0888910008531_,0.275686091,-0.138013044,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,421448,DB00480,10035526,28,67400,44,67618,0.076322672,0.638427593,0.382685734,1.048793824,0.17200904,DB0048010035526_,1.760208246,-0.448747011,NA,10035526,Platelet count abnormal,10022891,Investigations,Inv,lenalidomide,DB00480
,421486,DB00268,10022000,40,2935,10,1535,0.035502504,2.09169598,1.024421883,4.704032781,0.09649295,DB0026810022000_,2.33828533,0.73797521,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ropinirole,DB00268
,422094,DB00787,10014011,38,16962,32,17216,0.473836853,1.205273977,0.732856418,1.993774643,0.639721978,DB0078710014011_,0.446721607,0.186706908,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,acyclovir,DB00787
,422299,DB00264,10050819,47,29560,36,24856,0.741132525,1.097758989,0.695886068,1.744968712,0.851502247,DB0026410050819_,0.16075314,0.093270819,NA,10050819,Musculoskeletal chest pain,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,422901,DB01065,10030124,58,4273,27,3024,0.076644208,1.52015941,0.944792129,2.502985545,0.172637475,DB0106510030124_,1.756561405,0.418815204,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,melatonin,DB01065
,422960,DB00480,10061603,62,67366,38,67624,0.016296687,1.637811668,1.076292428,2.521621775,0.052585123,DB0048010061603_,2.945322039,0.493361002,NA,10061603,Respiratory syncytial virus infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,423637,DB01076,10028164,35,25712,22,25561,0.111066811,1.581543241,0.901858696,2.830919568,0.227703855,DB0107610028164_,1.479709375,0.458401105,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,atorvastatin,DB01076
,423670,DB11089,10056819,34,10141,18,8389,0.127524733,1.562516854,0.857315365,2.941024099,0.252114445,DB1108910056819_,1.377872148,0.446297889,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,docusate,DB11089
,424050,DB00804,10023003,41,2959,9,890,0.499289327,1.370090784,0.652702084,3.219114364,0.661116314,DB0080410023003_,0.413825488,0.314877003,NA,10023003,Irritable bowel syndrome,10017947,Gastrointestinal disorders,Gastr,dicyclomine,DB00804
,424273,DB00695,10052140,41,28008,13,20515,0.008202041,2.310035499,1.21309419,4.69945356,0.030405821,DB0069510052140_,3.493121212,0.837262892,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,furosemide,DB00695
,424353,DB01050,10001052,53,18055,9,9362,0.000703914,3.053443722,1.492245802,7.044558286,0.004112096,DB0105010001052_,5.493822523,1.116270043,female,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ibuprofen,DB01050
,424590,DB00268,10010264,90,2885,37,1508,0.254894594,1.271411121,0.853215167,1.928204806,0.415613933,DB0026810010264_,0.877998496,0.240127403,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ropinirole,DB00268
,424837,DB00531,10066901,114,7138,59,6457,0.000528326,1.747786111,1.263005144,2.440397342,0.003229169,DB0053110066901_,5.735530328,0.558349908,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,424908,DB11365,10040047,43,1602,44,1504,0.744589198,0.917523345,0.584730151,1.438838019,0.854143649,DB1136510040047_,0.157655892,-0.086077256,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,sennosides,DB11365
,425243,DB00364,10006451,46,2704,11,1389,0.023146522,2.147789445,1.091544479,4.613599018,0.069255133,DB0036410006451_,2.669958017,0.764439148,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,sucralfate,DB00364
,425321,DB01234,10018304,34,31591,23,32865,0.113390487,1.537855816,0.879621559,2.734912102,0.231178511,DB0123410018304_,1.464565092,0.430389119,NA,10018304,Glaucoma,10015919,Eye disorders,Eye,dexamethasone,DB01234
,425424,DB00341,10064848,31,11374,34,5034,0.000365184,0.403559056,0.239563749,0.677515545,0.002376248,DB0034110064848_,6.042232416,-0.907432443,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,cetirizine,DB00341
,425427,DB00706,10064848,8,1067,74,15851,0.247837566,1.605948559,0.666817195,3.34359739,0.407150651,DB0070610064848_,0.898572012,0.473714584,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,tamsulosin,DB00706
,425429,DB01060,10064848,114,8473,78,5003,0.32869379,0.86300001,0.63994282,1.168916631,0.497311795,DB0106010064848_,0.698538095,-0.147340577,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,amoxicillin,DB01060
,425435,DB00480,10034754,34,67394,22,67640,0.110499819,1.551081894,0.881162635,2.784136691,0.226806789,DB0048010034754_,1.483656773,0.438952684,NA,10034754,Petechiae,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,425444,DB00433,10040829,40,7616,10,6010,0.000504893,3.156201518,1.549517618,7.084453449,0.003114186,DB0043310040829_,5.771787495,1.149369253,female,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,prochlorperazine,DB00433
,425613,DB10631,10013968,55,1241,11,200,0.47249084,0.805925972,0.408362946,1.737564332,0.638497852,DB1063110013968_,0.448636968,-0.215763387,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cranberry,DB10631
,425742,DB00480,10039674,72,67356,57,67605,0.187217318,1.267822246,0.883093714,1.827703729,0.333035603,DB0048010039674_,1.099505879,0.237300662,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,425807,DB00410,10040753,57,1548,14,995,0.000751082,2.616129905,1.429867777,5.111789497,0.004337511,DB0041010040753_,5.440454552,0.96169609,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,mupirocin,DB00410
,426072,DB00213,10038683,38,18857,16,13405,0.096342352,1.688301612,0.91876952,3.244673961,0.205240404,DB0021310038683_,1.583573286,0.52372306,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pantoprazole,DB00213
,426140,DB00480,10023230,39,67389,32,67630,0.408692882,1.223104631,0.746589778,2.017070533,0.57808171,DB0048010023230_,0.548040054,0.201392406,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,426160,DB00497,10049414,25,19242,31,16344,0.179839107,0.68500743,0.387600527,1.199267114,0.323638978,DB0049710049414_,1.128126649,-0.378325594,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,426309,DB00996,10062189,40,38913,13,22412,0.085896763,1.77214186,0.92827213,3.612003798,0.188195193,DB0099610062189_,1.670275595,0.572188906,NA,10062189,Vitamin D decreased,10022891,Investigations,Inv,gabapentin,DB00996
,426763,DB00678,10048908,41,15558,16,10708,0.058479437,1.763634339,0.967857613,3.368276553,0.140659957,DB0067810048908_,1.961409957,0.567376645,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,losartan,DB00678
,426877,DB00863,10044034,41,10632,9,5831,0.011007218,2.498323611,1.195006415,5.850442701,0.038420869,DB0086310044034_,3.259154512,0.915619952,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,ranitidine,DB00863
,427013,DB00863,10017413,45,10628,25,5815,1,0.984845987,0.590438655,1.67775128,1,DB0086310017413_,0,-0.015270008,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,ranitidine,DB00863
,427488,DB06605,10030095,129,13944,72,12961,0.000493057,1.66532281,1.237389693,2.256300206,0.003058684,DB0660510030095_,5.789770572,0.510018985,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,427498,DB00588,10020765,39,16485,22,8446,0.786650387,0.908253386,0.524943482,1.609387393,0.884260501,DB0058810020765_,0.123003576,-0.096231879,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,fluticasone propionate,DB00588
,427638,DB00073,10052015,21,7385,34,6373,0.029268832,0.533038178,0.293650094,0.946326807,0.083090887,DB0007310052015_,2.48782025,-0.629162229,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,rituximab,DB00073
,427639,DB00531,10052015,168,7084,272,6244,7.52264315999109e-10,0.544438389,0.44506993,0.664389188,2.13951208353112e-08,DB0053110052015_,17.66010294,-0.608000495,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,cyclophosphamide,DB00531
,427643,DB01073,10052015,167,898,255,1395,0.870906614,1.017358426,0.817211344,1.264261555,0.94290223,DB0107310052015_,0.058792681,0.01720949,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,fludarabine,DB01073
,427683,DB00758,10075192,24,8276,38,10036,0.371083399,0.765904375,0.439082302,1.311527149,0.540698308,DB0075810075192_,0.614893811,-0.266697954,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,clopidogrel,DB00758
,427685,DB06605,10075192,45,14028,35,12998,0.501663982,1.191302517,0.748429978,1.910321471,0.663158206,DB0660510075192_,0.410741696,0.17504726,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,apixaban,DB06605
,427816,DB08895,10070325,123,27991,47,6599,0.006108095,0.616984922,0.436991877,0.88389979,0.024013053,DB0889510070325_,3.729157704,-0.482910694,NA,10070325,Mycobacterium tuberculosis complex test positive,10022891,Investigations,Inv,tofacitinib,DB08895
,427836,DB01234,10052239,31,31594,43,32845,0.245174552,0.749481715,0.456419559,1.217727775,0.403962458,DB0123410052239_,0.906433331,-0.288373357,NA,10052239,Full blood count increased,10022891,Investigations,Inv,dexamethasone,DB01234
,427848,DB01611,10047942,58,11855,10,2351,0.869766059,1.150204046,0.581753603,2.527873459,0.942090076,DB0161110047942_,0.059654387,0.139939358,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,hydroxychloroquine,DB01611
,428021,DB00182,10002368,31,5163,30,2822,0.030851301,0.564814525,0.329952,0.96810038,0.08659581,DB0018210002368_,2.446503853,-0.571257876,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,amphetamine,DB00182
,428591,DB09027,10016766,26,5153,36,7116,1,0.997348015,0.577432379,1.700765129,1,DB0902710016766_,0,-0.002655508,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,ledipasvir,DB09027
,429273,DB09035,10003239,59,4667,84,6606,1,0.994199795,0.698745906,1.40674616,1,DB0903510003239_,0,-0.005817091,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,nivolumab,DB09035
,429789,DB01373,10028164,48,22672,9,7372,0.164056139,1.734084031,0.841070654,4.021811814,0.302814094,DB0137310028164_,1.194636214,0.550479338,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,calcium,DB01373
,430028,DB08931,10042682,56,6521,18,2428,0.693841485,1.158354746,0.669248472,2.098168584,0.81567259,DB0893110042682_,0.203742243,0.147000676,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,430043,DB05351,10069339,186,2537,131,1000,2.27986607442479e-06,0.559776278,0.439683836,0.714065081,2.97179666581976e-05,DB0535110069339_,10.42375876,-0.580218078,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,dexlansoprazole,DB05351
,430045,DB01073,10011224,19,1046,43,1607,0.188509407,0.678935637,0.371479789,1.197939096,0.334654089,DB0107310011224_,1.094657851,-0.387228947,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fludarabine,DB01073
,430095,DB00273,10018100,47,8434,21,2172,0.048539494,0.5764098,0.336987807,1.017434143,0.122314314,DB0027310018100_,2.101161205,-0.550936414,NA,10018100,Generalised tonic-clonic seizure,10029205,Nervous system disorders,Nerv,topiramate,DB00273
,430295,DB00563,10013687,49,46597,20,15328,0.404502303,0.805916748,0.470121424,1.431821963,0.574271141,DB0056310013687_,0.554653624,-0.215774833,NA,10013687,Drug eruption,10040785,Skin and subcutaneous tissue disorders,Skin,methotrexate,DB00563
,430308,DB05676,10047899,170,46959,43,25286,3.38943399930054e-06,2.128812404,1.515111019,3.049522608,4.20241852224598e-05,DB0567610047899_,10.07726527,0.755564267,NA,10047899,Weight increased,10022891,Investigations,Inv,apremilast,DB05676
,430323,DB09052,10019211,43,886,46,1013,0.828068161,1.068715211,0.681390681,1.673538462,0.909617051,DB0905210019211_,0.094731591,0.06645719,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,blinatumomab,DB09052
,430330,DB09052,10028813,29,900,30,1029,0.791355502,1.10516582,0.634656903,1.9219104,0.887064667,DB0905210028813_,0.119837394,0.099995387,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,blinatumomab,DB09052
,430474,DB05676,10014011,107,47022,39,25290,0.037094746,1.475586421,1.013558677,2.188109229,0.099783594,DB0567610014011_,2.304751501,0.389055485,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,apremilast,DB05676
,430742,DB04868,10033371,50,1591,32,1484,0.116571141,1.457239922,0.911053453,2.361061132,0.235993596,DB0486810033371_,1.443950609,0.376544182,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,nilotinib,DB04868
,431029,DB06605,10001949,32,14041,24,13009,0.503767224,1.235323378,0.704694953,2.192866303,0.664885214,DB0660510001949_,0.408140863,0.21133278,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,431168,DB08904,10020937,84,11526,14,3545,0.03108035,1.845258143,1.039411306,3.524170698,0.08708528,DB0890410020937_,2.44086741,0.612619183,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,certolizumab pegol,DB08904
,431174,DB08904,10061428,42,11568,11,3548,0.74648773,1.171053491,0.591729738,2.524714493,0.855523435,DB0890410061428_,0.156041793,0.157903763,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,certolizumab pegol,DB08904
,431175,DB08904,10037884,54,11556,13,3546,0.474039352,1.274595844,0.685491914,2.549196097,0.63978996,DB0890410037884_,0.446615344,0.242629143,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,certolizumab pegol,DB08904
,431213,DB00364,10020642,30,2720,20,1380,0.367737391,0.761107658,0.416412163,1.419564677,0.537461554,DB0036410020642_,0.620898048,-0.272980462,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,sucralfate,DB00364
,431402,DB06186,10051792,15,2194,36,3610,0.247424464,0.685623965,0.347904645,1.287449687,0.406661867,DB0618610051792_,0.899773233,-0.377425958,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,ipilimumab,DB06186
,431410,DB00110,10037660,34,497,37,651,0.461506615,1.203464393,0.721428994,2.002376245,0.628745503,DB0011010037660_,0.46402871,0.185204392,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,palivizumab,DB00110
,431637,DB00973,10010264,56,3795,28,2993,0.059468442,1.577235009,0.982281998,2.585767479,0.142510643,DB0097310010264_,1.948338595,0.45567332,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ezetimibe,DB00973
,431758,DB00863,10039073,79,10594,8,5832,2.67519315960304e-08,5.43655816,2.62567284,13.03612923,5.45519411948533e-07,DB0086310039073_,14.42152745,1.69314617,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,431812,DB09038,10025482,27,2221,33,2508,0.795766811,0.923895803,0.532577619,1.590113799,0.889397596,DB0903810025482_,0.117210904,-0.079155981,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,empagliflozin,DB09038
,432018,DB00443,10025482,34,2112,19,1171,1,0.992175728,0.547283205,1.850078769,1,DB0044310025482_,0,-0.007855043,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,betamethasone,DB00443
,432019,DB00490,10025482,146,3924,30,1546,0.000824393,1.917207278,1.280834974,2.956059104,0.004693851,DB0049010025482_,5.361501844,0.650869584,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,432022,DB11750,10025482,51,2449,18,1495,0.045488329,1.729398058,0.988890398,3.158085009,0.116490719,DB1175010025482_,2.149943674,0.547773405,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,clobetasol,DB11750
,432357,DB06643,10015090,50,52371,19,7496,0.00073312,0.376673463,0.218058513,0.676939651,0.004249652,DB0664310015090_,5.460918182,-0.976376612,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,denosumab,DB06643
,432720,DB00635,10011490,17,33036,51,23743,4.00807679113477e-08,0.23957298,0.129661628,0.42190202,7.894514683775e-07,DB0063510011490_,14.05192748,-1.428897191,male,10011490,Cryptococcosis,10021881,Infections and infestations,Infec,prednisone,DB00635
,432870,DB00404,10028622,19,19873,32,9830,1.75461772817016e-05,0.293706281,0.157207471,0.534501835,0.000177898,DB0040410028622_,8.634298677,-1.225175054,male,10028622,Myoclonus,10029205,Nervous system disorders,Nerv,alprazolam,DB00404
,432998,DB13867,10000059,64,4486,35,2519,1,1.026785364,0.66764272,1.602601679,1,DB1386710000059_,0,0.026432916,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,fluticasone,DB13867
,433028,DB06724,10016766,55,7874,12,3907,0.008643904,2.274070218,1.201485448,4.672043781,0.031690495,DB0672410016766_,3.451738482,0.821571274,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,calcium carbonate,DB06724
,433588,DB00065,10043528,48,9416,15,4942,0.084233602,1.679468793,0.923389042,3.232481425,0.185464922,DB0006510043528_,1.684889517,0.518477549,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,infliximab,DB00065
,433894,DB00836,10007617,15,5520,35,4040,0.000132784,0.31370145,0.15894824,0.590411187,0.001015631,DB0083610007617_,6.892245068,-1.159313542,male,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,loperamide,DB00836
,433932,DB01611,10021143,50,11863,22,2339,0.003532106,0.448139024,0.265828409,0.778724436,0.01542985,DB0161110021143_,4.171451358,-0.802651774,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxychloroquine,DB01611
,434052,DB04951,10021240,15,1867,35,3022,0.30541444,0.693751682,0.351002722,1.307857183,0.472208349,DB0495110021240_,0.750334974,-0.36564119,NA,10021240,Idiopathic pulmonary fibrosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pirfenidone,DB04951
,434056,DB04951,10047895,86,1796,153,2904,0.538990431,0.908862233,0.684953585,1.199670225,0.694836238,DB0495110047895_,0.36407909,-0.095561755,NA,10047895,Weight decreased,10022891,Investigations,Inv,pirfenidone,DB04951
,434063,DB04951,10013573,113,1769,114,2943,0.000263051,1.648814301,1.251032007,2.173096203,0.001811682,DB0495110013573_,6.313499332,0.500056424,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pirfenidone,DB04951
,434265,DB08904,10042609,131,11479,36,3523,0.646089865,1.116796245,0.765507313,1.666484211,0.781649463,DB0890410042609_,0.246348896,0.110464091,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,certolizumab pegol,DB08904
,434391,DB05676,10040844,144,46985,88,25241,0.335435435,0.879083868,0.669348829,1.160032998,0.504645876,DB0567610040844_,0.683898332,-0.128874973,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,434653,DB00907,10000381,33,1105,35,1776,0.101145488,1.515125577,0.906818505,2.526768592,0.212544201,DB0090710000381_,1.548605307,0.415498325,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,cocaine,DB00907
,434731,DB05676,10060795,69,47060,31,25298,0.462925273,1.196495591,0.772322867,1.892226624,0.630118048,DB0567610060795_,0.4618481,0.179396944,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,apremilast,DB05676
,434813,DB00541,10066274,17,3117,34,4263,0.254795381,0.683865024,0.357603534,1.261213349,0.415516601,DB0054110066274_,0.878232711,-0.379994714,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,vincristine,DB00541
,435000,DB08932,10007739,58,19385,12,6585,0.130299703,1.641768578,0.871472713,3.361116445,0.256155544,DB0893210007739_,1.361970424,0.495774062,NA,10007739,Cataract,10015919,Eye disorders,Eye,macitentan,DB08932
,435222,DB01156,10043417,41,13581,16,6312,0.669201624,1.190940483,0.653407267,2.275371238,0.799162431,DB0115610043417_,0.224191061,0.174743317,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,435238,DB09183,10019211,28,447,30,697,0.170425347,1.454824676,0.825315879,2.557731304,0.311442295,DB0918310019211_,1.166541208,0.374885396,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,dasabuvir,DB09183
,435284,DB09183,10016256,49,426,73,654,0.922244849,1.030476298,0.687749238,1.533506921,0.965727381,DB0918310016256_,0.034873699,0.03002112,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dasabuvir,DB09183
,435288,DB09183,10002034,18,457,47,680,0.050229723,0.570109997,0.30748416,1.015393127,0.125425191,DB0918310002034_,2.076045783,-0.56192596,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,dasabuvir,DB09183
,435289,DB09183,10018884,28,447,43,684,1,0.996413118,0.586813586,1.668441709,1,DB0918310018884_,0,-0.00359333,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,dasabuvir,DB09183
,435312,DB00678,10029366,41,15558,23,10701,0.524522121,1.226081042,0.718160946,2.141681801,0.682646198,DB0067810029366_,0.381778565,0.203822938,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,losartan,DB00678
,435460,DB09073,10013709,284,19976,20,770,0.014188074,0.547404316,0.345370987,0.915054075,0.047086254,DB0907310013709_,3.055774166,-0.602567599,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,palbociclib,DB09073
,435463,DB09073,10019211,697,19563,18,772,0.087700969,1.528073995,0.953090571,2.608000191,0.191336319,DB0907310019211_,1.653722567,0.424008116,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,palbociclib,DB09073
,435718,DB00331,10013722,43,24903,32,20720,0.64485254,1.118008855,0.69087,1.826365752,0.780709787,DB0033110013722_,0.24755179,0.111549295,NA,10013722,Drug level increased,10022891,Investigations,Inv,metformin,DB00331
,435745,DB08934,10013786,35,4454,45,6159,0.820275837,1.075504773,0.669952026,1.713886094,0.904288487,DB0893410013786_,0.100606847,0.072790108,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,sofosbuvir,DB08934
,435871,DB11065,10033609,29,3157,32,2656,0.303783515,0.762472855,0.443752338,1.305068411,0.470325413,DB1106510033609_,0.754330455,-0.271188371,NA,10033609,Pancreatic carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,pancrelipase amylase,DB11065
,436003,DB01076,10051076,41,25706,39,25544,0.91103913,1.04466971,0.657011881,1.663511359,0.960010859,DB0107610051076_,0.040810683,0.043700769,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,436014,DB05676,10064355,185,46944,100,25229,0.950471501,0.994240137,0.774995,1.281756648,0.988726587,DB0567610064355_,0.01133744,-0.005776515,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,apremilast,DB05676
,436238,DB00544,10038435,30,2405,20,2633,0.089189863,1.642029935,0.899435012,3.059534736,0.193948752,DB0054410038435_,1.640161321,0.495933242,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,fluorouracil,DB00544
,436379,DB01238,10007617,43,5207,27,3475,0.902644491,1.062851305,0.640619805,1.79241083,0.957195726,DB0123810007617_,0.043747388,0.060955207,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,aripiprazole,DB01238
,436626,DB01593,10010774,41,1092,17,681,0.171869059,1.503721873,0.827842775,2.846868141,0.313274727,DB0159310010774_,1.160674751,0.407943284,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,zinc,DB01593
,436761,DB06684,10040108,16,731,40,295,1.80337983085496e-10,0.161733357,0.08318867,0.300736842,5.65654401599315e-09,DB0668410040108_,18.99045273,-1.821806244,male,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,vilazodone,DB06684
,438207,DB00627,10021097,18,1311,38,1561,0.056908778,0.564119877,0.301533927,1.018623121,0.137631434,DB0062710021097_,1.983175935,-0.572488502,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,niacin,DB00627
,438285,DB00762,10028116,17,1146,38,1331,0.028008266,0.519716516,0.273504328,0.949306204,0.080239485,DB0076210028116_,2.522739555,-0.654471777,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,irinotecan,DB00762
,438606,DB01248,10033775,45,2655,11,1363,0.023150853,2.099822596,1.065026546,4.51668412,0.069260205,DB0124810033775_,2.669884785,0.741852863,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,docetaxel,DB01248
,439706,DB01060,10013971,30,8557,21,5060,0.563706915,0.844772635,0.467228765,1.554258766,0.715608716,DB0106010013971_,0.334621748,-0.168687759,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amoxicillin,DB01060
,439837,DB00860,10010774,32,1851,19,1477,0.324176235,1.343794093,0.735414217,2.520003681,0.49261294,DB0086010010774_,0.708031525,0.295497026,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,prednisolone,DB00860
,440069,DB00860,10046571,47,1836,7,1489,1.14513762707009e-06,5.443159992,2.435385308,14.32025497,1.61393793713337e-05,DB0086010046571_,11.03424835,1.694359773,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,prednisolone,DB00860
,440179,DB00043,10022004,50,6363,19,2281,0.785731088,0.943367116,0.545079727,1.698149756,0.883734037,DB0004310022004_,0.123599125,-0.058299766,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,440180,DB00285,10022004,73,10878,11,3707,0.007983647,2.261560774,1.190896498,4.734214442,0.029740668,DB0028510022004_,3.515239885,0.816055183,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,venlafaxine,DB00285
,440754,DB00455,10061623,60,9341,37,5081,0.594099744,0.882086768,0.575128042,1.369006652,0.740127997,DB0045510061623_,0.300932139,-0.125464851,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,441318,DB00115,10062355,135,18290,77,10395,1,0.996445938,0.746862993,1.337476101,1,DB0011510062355_,0,-0.003560392,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,441515,DB00836,10044565,34,5501,42,4033,0.026479209,0.593539549,0.365487231,0.957491303,0.076813377,DB0083610044565_,2.56637647,-0.52165143,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,loperamide,DB00836
,441779,DB00115,10024384,35,18390,15,10457,0.381732892,1.326777404,0.705681475,2.616135629,0.551871357,DB0011510024384_,0.59444031,0.282752997,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,cyanocobalamin,DB00115
,441813,DB06273,10011906,115,4980,66,1344,3.78182184720357e-06,0.470301432,0.342287959,0.650615841,4.62242209968593e-05,DB0627310011906_,9.982006633,-0.754381445,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,441837,DB14513,10005724,44,7133,21,3543,1,1.040705494,0.604651354,1.845651569,1,DB1451310005724_,0,0.039898843,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,magnesium,DB14513
,442299,DB00572,10020937,45,2857,20,2106,0.076046787,1.658394523,0.956088958,2.974211944,0.171556434,DB0057210020937_,1.762843008,0.50584998,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,atropine,DB00572
,442863,DB01026,10025482,34,1076,24,1044,0.286909047,1.374331359,0.785297508,2.440302046,0.451689285,DB0102610025482_,0.794760758,0.317967328,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ketoconazole,DB01026
,443353,DB05679,10022086,49,6882,20,4889,0.037145196,1.740407765,1.014096176,3.095330738,0.099878971,DB0567910022086_,2.303796113,0.554119433,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,443483,DB00795,10037153,69,4500,29,1474,0.287750327,0.779390321,0.496094539,1.252840243,0.452756119,DB0079510037153_,0.792401667,-0.249243304,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,sulfasalazine,DB00795
,443513,DB08904,10046735,158,11452,33,3526,0.04765158,1.474096055,1.005705545,2.219832918,0.120672651,DB0890410046735_,2.114673763,0.388044958,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,certolizumab pegol,DB08904
,443641,DB00190,10038695,20,3277,31,4643,0.777833398,0.914085799,0.492859829,1.658979917,0.878859624,DB0019010038695_,0.129130094,-0.08983084,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,carbidopa,DB00190
,444072,DB00581,10022437,45,2068,31,2038,0.133477017,1.430426997,0.881484847,2.34838209,0.260627967,DB0058110022437_,1.344661301,0.357972999,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,lactulose,DB00581
,444195,DB08820,10000081,38,4363,38,3507,0.35547853,0.803830921,0.497840085,1.29784804,0.525225023,DB0882010000081_,0.643928493,-0.218366329,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,ivacaftor,DB08820
,444197,DB08820,10010774,68,4333,41,3504,0.146408043,1.341170972,0.894692562,2.03266311,0.278925522,DB0882010010774_,1.276810481,0.293543092,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ivacaftor,DB08820
,444202,DB11065,10019211,142,3044,64,2624,1.70876329160808e-05,1.912407434,1.407043859,2.623256569,0.000173886,DB1106510019211_,8.657108657,0.648362885,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pancrelipase amylase,DB11065
,445356,DB00959,10001760,74,8004,14,4988,7.25131481354208e-06,3.293737544,1.842278258,6.323379752,8.1838046317713e-05,DB0095910001760_,9.410768309,1.192022952,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,methylprednisolone,DB00959
,446111,DB00863,10013971,61,10612,28,5812,0.505121214,1.193124316,0.750093973,1.941182323,0.666037066,DB0086310013971_,0.406409956,0.176575342,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,446438,DB00381,10070488,37,29323,17,22870,0.074730099,1.697478202,0.931935037,3.215723688,0.169414866,DB0038110070488_,1.775404744,0.529143739,NA,10070488,Upper-airway cough syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amlodipine,DB00381
,446975,DB01076,10021027,64,25683,16,25567,5.809181526791e-08,3.981565159,2.274502369,7.381690737,1.10567948176467e-06,DB0107610021027_,13.7150505,1.381674998,female,10021027,Hypomagnesaemia,10027433,Metabolism and nutrition disorders,Metab,atorvastatin,DB01076
,447291,DB00586,10040047,53,7056,34,2771,0.030831347,0.612207335,0.389663735,0.973603101,0.086558913,DB0058610040047_,2.446930022,-0.49068427,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,diclofenac,DB00586
,447701,DB00678,10058080,35,15564,30,10694,0.378982938,0.801628688,0.477794892,1.352593271,0.548982753,DB0067810058080_,0.599688254,-0.221109761,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,losartan,DB00678
,447901,DB00874,10012378,48,3287,16,1960,0.050225826,1.788684604,0.994731467,3.383936261,0.125422604,DB0087410012378_,2.076066408,0.581480492,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,guaifenesin,DB00874
,447969,DB00497,10014062,32,19235,31,16344,0.615015881,0.877115091,0.518026085,1.486900316,0.756478122,DB0049710014062_,0.279081666,-0.131117062,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,oxycodone,DB00497
,448010,DB00921,10042674,43,5802,21,4882,0.043749771,1.72284796,0.998647026,3.060858153,0.113085133,DB0092110042674_,2.179614351,0.543978712,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,448192,DB01104,10040070,57,15406,20,7266,0.273299095,1.344185483,0.794607944,2.364000776,0.436259479,DB0110410040070_,0.829518078,0.295788241,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,sertraline,DB01104
,448201,DB01098,10051055,37,8112,44,7165,0.21929632,0.742759669,0.465854641,1.178315059,0.372629374,DB0109810051055_,0.98717099,-0.297382747,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,rosuvastatin,DB01098
,448479,DB00108,10047340,44,10150,8,3287,0.146642691,1.78099133,0.828252149,4.384891762,0.279240999,DB0010810047340_,1.275680073,0.577170136,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,natalizumab,DB00108
,448508,DB08895,10007739,89,28025,9,6637,0.009757928,2.341914498,1.178880515,5.291743174,0.034900956,DB0889510007739_,3.355241061,0.850968756,NA,10007739,Cataract,10015919,Eye disorders,Eye,tofacitinib,DB08895
,448520,DB08895,10017885,164,27950,20,6626,0.003405749,1.943885533,1.217313596,3.268551989,0.014991227,DB0889510017885_,4.200290088,0.664688822,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,448800,DB09035,10037377,43,4683,57,6633,0.760325036,1.068505424,0.700705555,1.618818996,0.866808794,DB0903510037377_,0.142936863,0.066260872,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nivolumab,DB09035
,448822,DB00465,10003239,47,2057,12,871,0.148689242,1.658191508,0.860850136,3.451513973,0.282177302,DB0046510003239_,1.265219674,0.505727555,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ketorolac,DB00465
,448914,DB01222,10022086,72,9202,20,5385,0.002271794,2.106618145,1.267390178,3.655392504,0.010792354,DB0122210022086_,4.52891737,0.745083887,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,budesonide,DB01222
,448974,DB00091,10041349,46,5464,9,2661,0.008971675,2.488912371,1.201396082,5.792586975,0.032637256,DB0009110041349_,3.422300834,0.911845816,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,cyclosporine,DB00091
,449086,DB00563,10067484,154,46492,34,15314,0.034205654,1.4918987,1.023141212,2.2327628,0.093812382,DB0056310067484_,2.366458423,0.400049604,NA,10067484,Adverse reaction,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,449724,DB08895,10006811,68,28046,7,6639,0.027487216,2.299535402,1.056891268,5.937666274,0.079078583,DB0889510006811_,2.537313198,0.832707103,NA,10006811,Bursitis,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,449784,DB00843,10025482,37,2157,33,2140,0.718242751,1.112347966,0.673964826,1.842994349,0.833604562,DB0084310025482_,0.181996135,0.106473066,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,donepezil,DB00843
,449788,DB00737,10040753,58,2743,9,923,0.031526747,2.16824244,1.061432411,4.997922117,0.088073179,DB0073710040753_,2.429587225,0.773916904,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,meclizine,DB00737
,449980,DB06262,10019196,28,3772,38,4276,0.536259673,0.835315134,0.492711151,1.400415416,0.692572681,DB0626210019196_,0.367342091,-0.179946219,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,droxidopa,DB06262
,450327,DB14513,10037153,62,7115,23,3541,0.249018229,1.341567883,0.817797812,2.272826887,0.408431857,DB1451310037153_,0.895430192,0.293838992,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,magnesium,DB14513
,450824,DB00207,10023232,35,9045,21,5434,1,1.001289761,0.566160579,1.812150338,1,DB0020710023232_,0,0.00128893,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,azithromycin,DB00207
,451188,DB01307,10012378,35,2489,19,2050,0.168930253,1.517065176,0.841432752,2.816511304,0.30939844,DB0130710012378_,1.173125384,0.416777663,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,insulin detemir,DB01307
,451592,DB00190,10019196,22,3275,34,4640,0.787000627,0.916742054,0.50978592,1.616951397,0.884476968,DB0019010019196_,0.122758806,-0.08692914,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,carbidopa,DB00190
,451700,DB13867,10042674,45,4505,10,2544,0.00469444,2.540892657,1.259664691,5.664449942,0.019444273,DB1386710042674_,3.94020272,0.932515459,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,451936,DB06186,10003658,22,2187,49,3597,0.268517297,0.738481943,0.423919566,1.248653684,0.430942554,DB0618610003658_,0.841780483,-0.303158629,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,ipilimumab,DB06186
,452154,DB00761,10054889,32,15275,18,8607,1,1.001723882,0.545201477,1.896613417,1,DB0076110054889_,0,0.001722398,NA,10054889,Transaminases increased,10022891,Investigations,Inv,potassium chloride,DB00761
,452305,DB00843,10037844,26,2168,41,2132,0.064936732,0.623686836,0.36488015,1.048479532,0.152350783,DB0084310037844_,1.881569633,-0.472106903,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,donepezil,DB00843
,452372,DB00275,10013700,65,1995,18,1219,0.002617138,2.206015476,1.285284181,3.971450528,0.012094139,DB0027510013700_,4.415034309,0.791187936,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,olmesartan,DB00275
,452545,DB00451,10025650,40,47231,16,15403,0.534224546,0.815290322,0.446321942,1.559994031,0.690843855,DB0045110025650_,0.36984145,-0.204211006,NA,10025650,Malignant melanoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,levothyroxine,DB00451
,452730,DB06589,10013573,30,2000,41,2612,0.904289022,0.955612015,0.573963709,1.574539426,0.957497529,DB0658910013573_,0.043432138,-0.04540329,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pazopanib,DB06589
,452862,DB06605,10066152,125,13948,89,12944,0.063462401,1.303381145,0.984132378,1.732170986,0.14971777,DB0660510066152_,1.89900329,0.264961769,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,apixaban,DB06605
,453733,DB01104,10056819,40,15423,20,7266,0.889892019,0.942232561,0.537529199,1.702488233,0.954356952,DB0110410056819_,0.046717514,-0.059503155,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,453764,DB01068,10047943,40,13723,16,6824,0.569990016,1.243121126,0.680228827,2.379689784,0.720782622,DB0106810047943_,0.327417683,0.217625254,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,clonazepam,DB01068
,453844,DB01115,10042674,39,3561,15,2253,0.121938076,1.644855599,0.884094967,3.219754689,0.244173414,DB0111510042674_,1.409876594,0.497652599,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,nifedipine,DB01115
,454113,DB01240,10023232,49,5702,16,1560,0.544533091,0.83787216,0.466859412,1.583069141,0.699501176,DB0124010023232_,0.357387803,-0.176889744,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,epoprostenol,DB01240
,454174,DB00321,10068319,42,7405,8,2842,0.079951393,2.014822627,0.93299477,4.974387901,0.178344496,DB0032110068319_,1.724038227,0.700531165,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amitriptyline,DB00321
,454252,DB06655,10003239,57,3631,20,2099,0.056754366,1.647389626,0.971530646,2.903509918,0.137346455,DB0665510003239_,1.985248679,0.49919199,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,liraglutide,DB06655
,454498,DB00864,10054889,34,6835,33,8359,0.389374146,1.26000407,0.756341293,2.101304627,0.559303756,DB0086410054889_,0.581062562,0.231114951,NA,10054889,Transaminases increased,10022891,Investigations,Inv,tacrolimus,DB00864
,454520,DB06723,10069339,52,978,41,569,0.184672668,0.738053292,0.473978814,1.155594067,0.329752459,DB0672310069339_,1.10941303,-0.303739246,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,aluminum hydroxide,DB06723
,454662,DB00368,10005483,24,636,37,761,0.360677954,0.77626869,0.439219488,1.348773072,0.530595892,DB0036810005483_,0.63375458,-0.253256568,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,norepinephrine,DB00368
,454937,DB01118,10035742,14,3049,36,4673,0.110689016,0.596062053,0.296456806,1.134712019,0.227115319,DB0111810035742_,1.482297378,-0.517410501,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amiodarone,DB01118
,455394,DB09027,10017885,32,5147,39,7113,0.63046281,1.133910252,0.686658721,1.860085163,0.769328241,DB0902710017885_,0.26223756,0.125672059,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,ledipasvir,DB09027
,455729,DB00043,10067482,268,6145,135,2165,0.001177439,0.699449338,0.563203585,0.871843741,0.006303254,DB0004310067482_,5.06668929,-0.357461914,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,455809,DB01267,10011906,31,2821,71,3644,0.008556354,0.564049625,0.356361105,0.874387066,0.031422111,DB0126710011906_,3.460243452,-0.572613044,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,456003,DB00563,10018627,34,46612,20,15328,0.040834801,0.559044444,0.312574056,1.025271251,0.107312813,DB0056310018627_,2.232007222,-0.581526303,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,methotrexate,DB00563
,456023,DB00476,10017918,43,17214,7,6170,0.052852281,2.201804404,0.981298095,5.80483769,0.130418909,DB0047610017918_,2.037003632,0.789277208,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,duloxetine,DB00476
,456227,DB05676,10040829,96,47033,40,25289,0.207375239,1.29047401,0.883359691,1.916400631,0.358067277,DB0567610040829_,1.027034385,0.255009601,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,456247,DB05676,10036790,68,47061,39,25290,0.761279921,0.936985268,0.622817541,1.427340852,0.867650712,DB0567610036790_,0.141966051,-0.065087719,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,456248,DB05676,10043521,41,47088,10,25319,0.02643235,2.20452808,1.085734392,4.936556336,0.076711307,DB0567610043521_,2.567706163,0.790513463,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,456302,DB05676,10037867,108,47021,64,25265,0.523261385,0.906719563,0.659233385,1.255841986,0.681579103,DB0567610037867_,0.383342962,-0.097922068,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,456500,DB05676,10040849,43,47086,35,25294,0.074520516,0.659951187,0.412477548,1.062583524,0.169049086,DB0567610040849_,1.777566156,-0.415589406,NA,10040849,Skin fissures,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,456826,DB00476,10038669,45,17212,24,6153,0.131210398,0.670293576,0.399403555,1.151292967,0.257531759,DB0047610038669_,1.356612232,-0.40003949,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,duloxetine,DB00476
,456840,DB00904,10003285,64,23005,21,14435,0.009857259,1.912262446,1.151834313,3.298076577,0.03516293,DB0090410003285_,3.347762886,0.648287068,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,457345,DB00997,10054236,31,5300,30,3484,0.148570999,0.679318526,0.396994589,1.163935733,0.282008602,DB0099710054236_,1.265817706,-0.386665151,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,doxorubicin,DB00997
,457488,DB00213,10075192,30,18865,21,13400,1,1.0147289,0.561692002,1.865585827,1,DB0021310075192_,0,0.014621483,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,pantoprazole,DB00213
,457489,DB00264,10075192,33,29574,56,24836,0.001289027,0.494889251,0.31167532,0.774564566,0.006779807,DB0026410075192_,4.99380666,-0.703421277,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,metoprolol,DB00264
,457491,DB00451,10075192,45,47226,19,15400,0.382874763,0.772325622,0.442526208,1.398646837,0.552974705,DB0045110075192_,0.59244302,-0.258349028,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,457493,DB01076,10075192,25,25722,45,25538,0.016610782,0.551591183,0.324068861,0.919231398,0.053385634,DB0107610075192_,2.930213594,-0.594948117,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,atorvastatin,DB01076
,457519,DB01409,10070863,12,6019,40,3926,7.25222197177908e-08,0.195711371,0.093336698,0.381126469,1.35338767858156e-06,DB0140910070863_,13.51289972,-1.631114303,male,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,tiotropium,DB01409
,457558,DB00203,10029216,59,13819,15,8923,0.000730802,2.539671894,1.421449985,4.82359969,0.004241364,DB0020310029216_,5.462870326,0.932034897,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,sildenafil,DB00203
,457588,DB00688,10025127,33,6457,44,5334,0.038908267,0.619593557,0.381598555,0.997086252,0.103444475,DB0068810025127_,2.268720285,-0.478691568,NA,10025127,Lung transplant,10042613,Surgical and medical procedures,Surg,mycophenolate mofetil,DB00688
,457589,DB00864,10025127,55,6814,54,8338,0.287867421,1.246293585,0.839177522,1.851647636,0.452845482,DB0086410025127_,0.792204312,0.220174015,NA,10025127,Lung transplant,10042613,Surgical and medical procedures,Surg,tacrolimus,DB00864
,457726,DB00193,10076308,125,19195,45,8657,0.21267703,1.25274856,0.883523054,1.804740131,0.364634774,DB0019310076308_,1.008859045,0.225339985,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,457731,DB00695,10076308,139,27910,73,20455,0.02142709,1.395494942,1.043174931,1.879974986,0.065296048,DB0069510076308_,2.728823763,0.333249149,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,457733,DB00863,10076308,66,10607,29,5811,0.389263191,1.246848766,0.793266414,2.004186354,0.559159657,DB0086310076308_,0.581320235,0.220619381,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,457896,DB06262,10035664,45,3755,83,4231,0.009364551,0.610934563,0.414091486,0.891151185,0.033776634,DB0626210035664_,3.387986007,-0.492765424,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,droxidopa,DB06262
,457948,DB01211,10013709,50,1602,37,750,0.046455179,0.632772646,0.401553478,1.004984087,0.118424437,DB0121110013709_,2.133480183,-0.457644091,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,clarithromycin,DB01211
,458058,DB06403,10052904,40,21431,11,6650,0.869203587,1.128351142,0.567812633,2.439739684,0.941834294,DB0640310052904_,0.059925929,0.120757401,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,458238,DB06228,10049771,52,15860,67,16009,0.199025754,0.783418656,0.534253426,1.143204185,0.347878171,DB0622810049771_,1.055902943,-0.244088044,NA,10049771,Shock haemorrhagic,10047065,Vascular disorders,Vasc,rivaroxaban,DB06228
,458573,DB01611,10014387,80,11833,56,2305,6.75709931155919e-12,0.278312228,0.19473136,0.400122884,2.6688257761733e-10,DB0161110014387_,22.04421234,-1.279011674,male,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,hydroxychloroquine,DB01611
,458649,DB00619,10037087,57,2842,36,2458,0.17234627,1.369318146,0.883285908,2.14772101,0.31392687,DB0061910037087_,1.158595219,0.314312912,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,imatinib,DB00619
,458901,DB01036,10033371,50,1451,14,408,1,1.004231561,0.539910771,1.987617448,1,DB0103610033371_,0,0.004222633,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,tolterodine,DB01036
,458911,DB00695,10075192,54,27995,50,20478,0.23446615,0.790016966,0.52747213,1.1852535,0.3913725,DB0069510075192_,0.938095488,-0.235700857,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,furosemide,DB00695
,459243,DB04951,10038695,25,1857,55,3002,0.245622268,0.734855885,0.437182651,1.204143557,0.404497295,DB0495110038695_,0.90511023,-0.308080873,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pirfenidone,DB04951
,459268,DB09027,10027599,49,5130,34,7118,0.002378467,1.999582645,1.262966265,3.198706128,0.01120795,DB0902710027599_,4.4911319,0.692938481,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,ledipasvir,DB09027
,459293,DB01142,10022437,42,1698,21,763,0.681056587,0.898747912,0.516281245,1.609182384,0.807122451,DB0114210022437_,0.214279887,-0.106752693,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,doxepin,DB01142
,459405,DB06724,10029366,38,7891,23,3896,0.495202354,0.81575423,0.472918402,1.436380576,0.657509856,DB0672410029366_,0.419295525,-0.203642158,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,calcium carbonate,DB06724
,459742,DB08889,10061024,23,3142,50,3835,0.024111945,0.561502737,0.32622235,0.939847372,0.07150073,DB0888910061024_,2.638047614,-0.57713863,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,carfilzomib,DB08889
,459849,DB13867,10021097,81,4469,53,2501,0.413462785,0.855314047,0.59536334,1.23762153,0.582852585,DB1386710021097_,0.539820981,-0.156286571,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,fluticasone,DB13867
,459985,DB09065,10062180,6,746,49,1888,0.003490473,0.31002762,0.108064922,0.728605666,0.015293371,DB0906510062180_,4.180335819,-1.171093888,male,10062180,Viral load increased,10022891,Investigations,Inv,cobicistat,DB09065
,460247,DB00231,10033295,32,3264,19,2120,0.88566366,1.093910094,0.599670144,2.048334719,0.952411128,DB0023110033295_,0.04875848,0.08975852,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,temazepam,DB00231
,460483,DB14500,10008469,54,7755,17,4056,0.07844334,1.661284283,0.946882056,3.061092391,0.175763635,DB1450010008469_,1.738615169,0.507590967,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,potassium,DB14500
,460577,DB00537,10009657,39,7518,25,4273,0.695987627,0.886668609,0.522408871,1.530936944,0.817040153,DB0053710009657_,0.202067039,-0.120283975,NA,10009657,Clostridium difficile colitis,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,460732,DB09035,10003988,72,4654,97,6593,0.753518348,1.051488856,0.762346215,1.444744986,0.86133778,DB0903510003988_,0.14926854,0.050207118,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,nivolumab,DB09035
,460761,DB00635,10043709,42,33011,8,23786,0.000139147,3.782769133,1.754036523,9.329414277,0.00105753,DB0063510043709_,6.851818883,1.330456316,female,10043709,Thyroid disorder,10014698,Endocrine disorders,Endo,prednisone,DB00635
,460859,DB00227,10028810,58,2409,25,1778,0.024815224,1.712101499,1.049425032,2.868357661,0.073083268,DB0022710028810_,2.616155827,0.537721563,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,lovastatin,DB00227
,460905,DB09034,10067482,37,1139,23,655,0.786198867,0.925146233,0.530082082,1.646146629,0.88396087,DB0903410067482_,0.123342482,-0.077803464,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,suvorexant,DB09034
,461050,DB09122,10022095,84,1174,18,319,0.45184407,1.267842306,0.742132815,2.27654041,0.619465649,DB0912210022095_,0.478898029,0.237316484,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,peginterferon beta-1a,DB09122
,461124,DB08889,10005750,30,3135,34,3851,0.801116878,1.083859908,0.63918064,1.829551076,0.892412152,DB0888910005750_,0.113827199,0.080528659,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,carfilzomib,DB08889
,461267,DB06605,10044034,40,14033,38,12995,0.910287124,0.974765257,0.609077165,1.562562032,0.959579421,DB0660510044034_,0.041260194,-0.025558599,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,461441,DB01156,10029148,36,13586,18,6310,0.771697546,0.928902605,0.51341729,1.739079308,0.875048856,DB0115610029148_,0.133475559,-0.073751384,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,bupropion,DB01156
,461448,DB00927,10070863,48,7449,29,4987,0.7269997,1.108128618,0.683648022,1.825114945,0.840370601,DB0092710070863_,0.173912292,0.102672663,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,famotidine,DB00927
,461449,DB00331,10013654,32,24914,19,20733,0.26265357,1.40155817,0.770395369,2.617938994,0.42440841,DB0033110013654_,0.857059056,0.337584596,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,metformin,DB00331
,461517,DB00853,10016288,15,1806,38,2228,0.017731173,0.487060975,0.248039406,0.909795801,0.056220011,DB0085310016288_,2.878482513,-0.719365959,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,temozolomide,DB00853
,461530,DB00381,10065154,173,29187,138,22749,0.863538161,0.977095369,0.776181643,1.231994978,0.937043613,DB0038110065154_,0.065025453,-0.023171017,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,amlodipine,DB00381
,461766,DB00814,10027175,114,8173,35,3380,0.146347118,1.346936579,0.912933091,2.032053249,0.278829661,DB0081410027175_,1.277154216,0.297832813,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,meloxicam,DB00814
,461768,DB06262,10027175,65,3735,49,4265,0.029767006,1.514674251,1.026506342,2.24754702,0.084204236,DB0626210027175_,2.474510049,0.4152004,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,461786,DB06262,10048959,33,3767,43,4271,0.565897751,0.870135792,0.534386696,1.405292657,0.717402449,DB0626210048959_,0.3321183,-0.139105997,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,461821,DB00051,10040808,45,25686,47,11373,5.72754460618243e-05,0.423935938,0.275153368,0.652468486,0.000495551,DB0005110040808_,7.609839511,-0.858172926,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,adalimumab,DB00051
,461926,DB11065,10037844,70,3116,34,2654,0.007196987,1.75340189,1.143995381,2.734051775,0.027370732,DB1106510037844_,3.598281021,0.561557838,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,pancrelipase amylase,DB11065
,462054,DB00264,10021113,82,29525,8,24884,5.67150801976694e-14,8.636867449,4.183158922,20.67487169,3.00555621571722e-12,DB0026410021113_,26.53055847,2.156039953,female,10021113,Hypothermia,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,462249,DB00682,10022840,20,19439,42,16322,0.000512398,0.399842896,0.222300733,0.696737725,0.003149762,DB0068210022840_,5.760428502,-0.916683569,NA,10022840,Intraventricular haemorrhage,10029205,Nervous system disorders,Nerv,warfarin,DB00682
,462496,DB00381,10071066,43,29317,11,22876,0.000482979,3.050121618,1.546426247,6.559610943,0.003004049,DB0038110071066_,5.807794247,1.115181464,female,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,462563,DB00567,10035528,32,4487,25,2056,0.061411669,0.586557536,0.335814503,1.0353025,0.146055531,DB0056710035528_,1.923768384,-0.533484516,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,cephalexin,DB00567
,462565,DB00567,10047942,53,4466,25,2056,0.902978157,0.975981562,0.593959053,1.64393621,0.957326661,DB0056710047942_,0.043610607,-0.024311584,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,cephalexin,DB00567
,463096,DB00927,10017944,40,7457,14,5002,0.036516223,1.916414241,1.019451821,3.817752422,0.098611359,DB0092710017944_,2.316568825,0.650455857,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,famotidine,DB00927
,463103,DB14513,10017944,41,7136,15,3549,0.393165619,1.35937488,0.735459637,2.647673399,0.563072891,DB1451310017944_,0.574346191,0.307024947,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,magnesium,DB14513
,463376,DB00333,10020993,17,3054,42,3110,0.001550473,0.412213472,0.219517804,0.741771784,0.007902239,DB0033310020993_,4.840609179,-0.886213927,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,methadone,DB00333
,463396,DB01222,10070863,20,9254,31,5374,0.000658431,0.374684358,0.20218789,0.679427349,0.003894869,DB0122210070863_,5.548095126,-0.981671319,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,budesonide,DB01222
,463525,DB01060,10008469,44,8543,23,5058,0.704472197,1.132655552,0.668387517,1.967541738,0.822852076,DB0106010008469_,0.194978832,0.124564922,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,463532,DB00972,10010264,35,2469,19,1160,0.659681996,0.865512488,0.479318787,1.609120253,0.792130711,DB0097210010264_,0.233028861,-0.144433476,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,azelastine,DB00972
,463566,DB00203,10041807,40,13838,13,8925,0.033756453,1.984442343,1.039054399,4.046334663,0.092900352,DB0020310041807_,2.376227845,0.685337939,NA,10041807,Sputum discoloured,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,464167,DB00210,10013786,129,756,42,307,0.272580127,1.247089241,0.850388935,1.857584469,0.435535008,DB0021010013786_,0.831180101,0.220812229,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,adapalene,DB00210
,464170,DB00210,10040844,99,786,29,320,0.147325865,1.389490228,0.889886957,2.226125295,0.280196836,DB0021010040844_,1.272262937,0.328936938,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,adapalene,DB00210
,464196,DB00480,10048762,90,67338,72,67590,0.157500138,1.254673032,0.909915914,1.73541925,0.294183061,DB0048010048762_,1.223553048,0.226875007,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,464199,DB00996,10048762,36,38917,16,22409,0.471716281,1.29558867,0.700678639,2.501026816,0.637844665,DB0099610048762_,0.449660497,0.258965163,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,gabapentin,DB00996
,464263,DB09034,10000125,41,1135,30,648,0.316891366,0.780387327,0.470383253,1.307903755,0.484694158,DB0903410000125_,0.724237189,-0.24796491,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,suvorexant,DB09034
,464264,DB09034,10002855,37,1139,17,661,0.475885141,1.262893598,0.687194285,2.411827568,0.64142018,DB0903410002855_,0.44407053,0.233405594,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,suvorexant,DB09034
,464265,DB09034,10016256,68,1108,21,657,0.009252486,1.919446325,1.149320608,3.329528656,0.033450464,DB0903410016256_,3.397689613,0.652036772,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,suvorexant,DB09034
,464359,DB08893,10011906,68,2017,68,990,5.96661066639529e-05,0.490935847,0.342446028,0.703861909,0.000513363,DB0889310011906_,7.574527585,-0.711441817,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,mirabegron,DB08893
,464879,DB08889,10053762,286,2879,345,3540,0.833952898,1.019317403,0.861620584,1.205183997,0.913732885,DB0888910053762_,0.090216998,0.01913319,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,carfilzomib,DB08889
,464952,DB04951,10047700,108,1774,62,2995,9.9763624679504e-12,2.940198481,2.11925506,4.108933034,3.8142354541102e-10,DB0495110047700_,21.68711069,1.07847709,female,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pirfenidone,DB04951
,464964,DB00563,10073753,193,46453,43,15305,0.019051413,1.478754042,1.057329673,2.110190445,0.059480507,DB0056310073753_,2.82210664,0.39119987,NA,10073753,Fear of injection,10037175,Psychiatric disorders,Psych,methotrexate,DB00563
,465116,DB01137,10059866,15,7757,38,5555,1.63416919767304e-05,0.28270861,0.144290526,0.526687088,0.000167007,DB0113710059866_,8.697476298,-1.263338559,male,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,465183,DB01115,10013971,62,3538,14,2254,0.000194687,2.820923979,1.5571781,5.469270241,0.001408764,DB0111510013971_,6.565042449,1.037064484,female,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nifedipine,DB01115
,465188,DB00524,10033557,48,1529,12,1332,3.41869232868212e-05,3.483169662,1.813223803,7.235874849,0.000318146,DB0052410033557_,8.053000271,1.247942702,female,10033557,Palpitations,10007541,Cardiac disorders,Card,metolazone,DB00524
,465292,DB01229,10018964,14,5727,39,2670,6.07421049236853e-10,0.167401099,0.083801464,0.315800003,1.75547688611222e-08,DB0122910018964_,17.85794019,-1.787362553,male,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,paclitaxel,DB01229
,465504,DB09122,10022004,148,1110,57,280,0.016861899,0.655160626,0.465432863,0.931230345,0.054057204,DB0912210022004_,2.917712466,-0.422874843,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,peginterferon beta-1a,DB09122
,465607,DB00874,10028735,44,3291,12,1964,0.017286441,2.187902911,1.132476444,4.562047771,0.055119076,DB0087410028735_,2.89825941,0.78294351,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,guaifenesin,DB00874
,465967,DB00310,10069339,33,911,24,757,0.685744565,1.142469824,0.648696343,2.039295904,0.810285273,DB0031010069339_,0.210368904,0.133192431,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,chlorthalidone,DB00310
,465968,DB09038,10069339,29,2219,72,2469,0.000176854,0.44824603,0.279645479,0.701715486,0.001299386,DB0903810069339_,6.645863541,-0.802413023,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,empagliflozin,DB09038
,466056,DB00864,10054236,52,6817,40,8352,0.027426686,1.592653249,1.033062486,2.471778455,0.078947648,DB0086410054236_,2.538970334,0.465401335,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,466091,DB09034,10016322,76,1100,25,653,0.010738854,1.804124456,1.121600576,2.991398394,0.037683835,DB0903410016322_,3.27852406,0.590075408,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,suvorexant,DB09034
,466108,DB00928,10018884,23,812,32,1254,0.780013886,1.109933609,0.615439164,1.972896007,0.880263829,DB0092810018884_,0.12753361,0.104300201,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,azacitidine,DB00928
,466231,DB00222,10006451,35,3171,16,3112,0.010959696,2.146542301,1.154436886,4.162770819,0.03830538,DB0022210006451_,3.262164919,0.763858315,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,glimepiride,DB00222
,466251,DB06404,10067482,317,2752,119,781,0.017938358,0.756044577,0.601047579,0.955517098,0.056719566,DB0640410067482_,2.869636049,-0.27965494,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,human c1-esterase inhibitor,DB06404
,466295,DB00175,10013971,47,8084,26,6080,0.236262558,1.359540761,0.823824591,2.289629349,0.393455445,DB0017510013971_,0.932787446,0.307146967,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pravastatin,DB00175
,466304,DB00688,10030095,38,6452,24,5354,0.309170683,1.313850548,0.766868434,2.29286413,0.476536394,DB0068810030095_,0.741211182,0.272962175,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,466672,DB01413,10054236,31,1189,19,1640,0.005727575,2.249831781,1.224650318,4.237363929,0.022813958,DB0141310054236_,3.780382728,0.810855449,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,cefepime,DB01413
,466713,DB00423,10033425,65,2402,18,1022,0.114881463,1.536283385,0.894799096,2.76664056,0.233466774,DB0042310033425_,1.454715507,0.429366113,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,methocarbamol,DB00423
,466760,DB00051,10064882,43,25688,25,11395,0.29345762,0.762961447,0.455351745,1.304227532,0.459125237,DB0005110064882_,0.77843226,-0.270547777,NA,10064882,Procedural pain,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,466773,DB01050,10048010,53,18055,23,9348,0.54532713,1.193049503,0.71814579,2.041032753,0.700091683,DB0105010048010_,0.356543976,0.176512637,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,466774,DB01224,10048010,47,8061,26,5891,0.285675967,1.321039757,0.800478823,2.224891447,0.450300908,DB0122410048010_,0.797839235,0.278419121,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,quetiapine,DB01224
,466879,DB01013,10053762,43,974,17,590,0.173536499,1.531809817,0.846469075,2.892563795,0.315509405,DB0101310053762_,1.153566789,0.426449924,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,clobetasol propionate,DB01013
,466963,DB01098,10017413,37,8112,37,7172,0.641186752,0.884130198,0.544507539,1.435574549,0.777959881,DB0109810017413_,0.251080323,-0.123150944,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,rosuvastatin,DB01098
,467308,DB00423,10020937,41,2426,12,1028,0.291783923,1.447686723,0.742684407,3.038774871,0.457206032,DB0042310020937_,0.782621154,0.369966919,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,methocarbamol,DB00423
,467436,DB00741,10037153,57,4037,25,3149,0.018217685,1.778333689,1.090424403,2.977951601,0.057389711,DB0074110037153_,2.857890236,0.575676796,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,hydrocortisone,DB00741
,467471,DB05676,10047571,46,47083,15,25314,0.1064646,1.648770925,0.903772472,3.180096942,0.220800299,DB0567610047571_,1.51049661,0.500030116,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,apremilast,DB05676
,467639,DB00316,10062016,38,65436,12,36941,0.078565169,1.787687827,0.914377329,3.758000754,0.175924135,DB0031610062016_,1.737702425,0.580923068,NA,10062016,Immunosuppression,10021428,Immune system disorders,Immun,acetaminophen,DB00316
,467661,DB09570,10013573,85,3816,77,3858,0.525569738,1.116029766,0.807390494,1.544639793,0.683569636,DB0957010013573_,0.380426747,0.109777535,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ixazomib,DB09570
,467663,DB00480,10038743,42,67386,38,67624,0.656377839,1.109162797,0.697925626,1.767884495,0.789930994,DB0048010038743_,0.235809687,0.103605494,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,467668,DB00051,10002368,33,25698,20,11400,0.297019362,0.731955629,0.407557305,1.346723006,0.462879313,DB0005110002368_,0.770288921,-0.312035383,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,adalimumab,DB00051
,467736,DB00987,10029350,42,2062,50,2878,0.45706778,1.172373332,0.755776478,1.810796897,0.624380979,DB0098710029350_,0.470994554,0.159030183,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,cytarabine,DB00987
,468222,DB00924,10019974,52,10110,9,4242,0.010760546,2.424146115,1.182359383,5.600630851,0.037749875,DB0092410019974_,3.27677311,0.885479345,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,cyclobenzaprine,DB00924
,468376,DB01222,10043554,34,9240,29,5376,0.149487539,0.682176184,0.402882107,1.162064299,0.28324256,DB0122210043554_,1.261451647,-0.38246732,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,budesonide,DB01222
,468378,DB01075,10044034,33,19915,19,11078,0.885921608,0.966114852,0.533227228,1.79923207,0.952535694,DB0107510044034_,0.048627699,-0.034472558,NA,10044034,Tooth disorder,10017947,Gastrointestinal disorders,Gastr,diphenhydramine,DB01075
,468389,DB00787,10022687,26,16974,33,17215,0.4353095,0.799072043,0.458754091,1.378236778,0.60372564,DB0078710022687_,0.504635422,-0.224304171,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,acyclovir,DB00787
,468391,DB01104,10022687,42,15421,9,7277,0.034138666,2.202083534,1.055853895,5.147968629,0.093685684,DB0110410022687_,2.367809888,0.789403973,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,sertraline,DB01104
,468558,DB01098,10039101,54,8095,34,7175,0.133641552,1.407697333,0.898784728,2.232779545,0.260830555,DB0109810039101_,1.343884297,0.341955272,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rosuvastatin,DB01098
,468650,DB00331,10061148,38,24908,13,20739,0.004513919,2.433713647,1.26775625,4.980522063,0.018816646,DB0033110061148_,3.973013375,0.889418341,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,468651,DB00381,10061148,39,29321,27,22860,0.710083873,1.126121722,0.671809048,1.913545102,0.827117597,DB0038110061148_,0.189808397,0.118779625,NA,10061148,Feeding disorder,10027433,Metabolism and nutrition disorders,Metab,amlodipine,DB00381
,468693,DB01373,10058920,54,22666,8,7373,0.03736158,2.195516808,1.037900864,5.345092121,0.10030633,DB0137310058920_,2.299526479,0.786417467,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,calcium,DB01373
,469026,DB09052,10053762,50,879,84,975,0.025002962,0.660385207,0.450184419,0.960510444,0.073475639,DB0905210053762_,2.610801368,-0.414931968,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,blinatumomab,DB09052
,469082,DB00335,10039020,11,8455,44,5421,7.64474721000308e-10,0.160309692,0.074613587,0.315790859,2.17234789637763e-08,DB0033510039020_,17.64487218,-1.830647759,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,atenolol,DB00335
,469114,DB01076,10058920,40,25707,23,25560,0.042896062,1.729157093,1.010172186,3.026625245,0.111497948,DB0107610058920_,2.193749091,0.547634061,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,atorvastatin,DB01076
,469137,DB01175,10017413,41,10683,16,4876,0.669199417,1.16957029,0.641528376,2.234920522,0.799162431,DB0117510017413_,0.224191061,0.156636408,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,escitalopram,DB01175
,469389,DB00480,10060961,34,67394,23,67639,0.147253699,1.48362287,0.848714096,2.638195692,0.280100117,DB0048010060961_,1.272608179,0.394486981,NA,10060961,Appetite disorder,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,469448,DB00316,10005619,65,65409,27,36926,0.193497349,1.359073886,0.855233991,2.215262845,0.341061379,DB0031610005619_,1.07569282,0.306803501,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,acetaminophen,DB00316
,469852,DB00215,10064848,39,11064,18,5258,1,1.02970287,0.574556021,1.914149623,1,DB0021510064848_,0,0.029270285,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,citalopram,DB00215
,469864,DB13961,10064848,53,9404,34,6380,0.827486326,1.057564064,0.673916212,1.680003991,0.909224901,DB1396110064848_,0.0951628,0.055968211,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,fish oil,DB13961
,469916,DB00531,10022000,36,7216,37,6479,0.638599874,0.87360874,0.535843227,1.423074453,0.775774702,DB0053110022000_,0.253893133,-0.135122669,NA,10022000,Influenza,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,470142,DB00480,10013578,24,67404,33,67629,0.289183082,0.729704868,0.412627632,1.272804997,0.454298712,DB0048010013578_,0.789000342,-0.315115116,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,470155,DB00404,10019974,83,19809,20,9842,0.00310446,2.061861963,1.252719256,3.55019668,0.01391317,DB0040410019974_,4.274919395,0.72360944,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,alprazolam,DB00404
,470570,DB00230,10029148,47,19627,21,8630,1,0.984091675,0.57637675,1.734183151,1,DB0023010029148_,0,-0.016036221,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,pregabalin,DB00230
,470662,DB00169,10052251,42,38649,27,18148,0.199062667,0.730409151,0.439782835,1.232374455,0.347896422,DB0016910052251_,1.055850481,-0.31415042,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cholecalciferol,DB00169
,470673,DB08895,10006784,97,28017,11,6635,0.01904669,2.08826024,1.116117121,4.324154907,0.059479891,DB0889510006784_,2.822116987,0.736331298,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,470735,DB01224,10049848,56,8052,37,5880,0.674480748,1.105269133,0.715773362,1.724697713,0.802604304,DB0122410049848_,0.219893459,0.100088865,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,quetiapine,DB01224
,470780,DB00787,10036018,31,16969,36,17212,0.625677871,0.873446435,0.522230856,1.453172099,0.765247911,DB0078710036018_,0.267555432,-0.135308473,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,acyclovir,DB00787
,470907,DB00737,10037844,76,2725,20,912,0.403262324,1.271689448,0.7637634,2.210581655,0.573021417,DB0073710037844_,0.556832186,0.240346291,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,meclizine,DB00737
,470928,DB00741,10047942,58,4036,40,3134,0.608910023,1.12589333,0.737563478,1.733921967,0.751453118,DB0074110047942_,0.285746456,0.118576792,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,hydrocortisone,DB00741
,470969,DB00115,10013538,68,18357,29,10443,0.20559556,1.333921615,0.851256909,2.138849963,0.355967291,DB0011510013538_,1.032916431,0.288123187,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,471199,DB00813,10029366,34,10538,19,10149,0.072728582,1.723363925,0.954782125,3.200595559,0.166073389,DB0081310029366_,1.795325488,0.544278151,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,fentanyl,DB00813
,471300,DB00331,10017412,56,24890,38,20714,0.352012483,1.22642572,0.79767625,1.904166314,0.521756877,DB0033110017412_,0.650553553,0.20410402,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,metformin,DB00331
,471389,DB01377,10022000,49,3747,38,2632,0.662162628,0.905778268,0.579038998,1.426519934,0.794021198,DB0137710022000_,0.23064512,-0.09896074,NA,10022000,Influenza,10021881,Infections and infestations,Infec,magnesium oxide,DB01377
,471475,DB11089,10060795,34,10141,28,8379,1,1.003303295,0.589938923,1.71920472,1,DB1108910060795_,0,0.003297852,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,docusate,DB11089
,471571,DB01222,10038435,57,9217,46,5359,0.101630121,0.720501258,0.479213992,1.088359786,0.213349392,DB0122210038435_,1.544824118,-0.327808117,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,budesonide,DB01222
,471582,DB01097,10028334,48,6217,13,1490,0.744392067,0.884909609,0.470398774,1.785209279,0.854015342,DB0109710028334_,0.157806121,-0.122269776,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,leflunomide,DB01097
,471614,DB00213,10020765,45,18850,24,13397,0.273137245,1.332580433,0.794361234,2.288123224,0.436117019,DB0021310020765_,0.829844679,0.287117237,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,471615,DB00215,10020765,33,11070,23,5253,0.154857352,0.680845327,0.387446184,1.215714284,0.290609752,DB0021510020765_,1.235773972,-0.384420125,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,citalopram,DB00215
,471624,DB00264,10053156,44,29563,15,24877,0.001594204,2.468261261,1.347048778,4.776317795,0.00807392,DB0026410053156_,4.819116122,0.90351396,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,metoprolol,DB00264
,471627,DB00480,10053156,37,67391,22,67640,0.051460134,1.688015283,0.969829338,3.004481408,0.127751227,DB0048010053156_,2.057670447,0.52355345,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,lenalidomide,DB00480
,471666,DB00480,10062080,37,67391,17,67645,0.006359086,2.184650952,1.199641319,4.137863389,0.024806853,DB0048010062080_,3.696635324,0.781456068,NA,10062080,Pigmentation disorder,10040785,Skin and subcutaneous tissue disorders,Skin,lenalidomide,DB00480
,471680,DB00047,10022061,45,9240,16,8502,0.000726418,2.587581016,1.43358265,4.908638167,0.004220576,DB0004710022061_,5.46778363,0.950723469,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,insulin glargine,DB00047
,471761,DB00437,10019063,24,6897,64,11482,0.047498416,0.6243084,0.373007157,1.013297149,0.120400778,DB0043710019063_,2.116929284,-0.471110802,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,allopurinol,DB00437
,471880,DB00169,10061016,36,38655,22,18153,0.3269507,0.768436017,0.439860414,1.371711595,0.495363844,DB0016910061016_,0.702462748,-0.263397977,NA,10061016,Blood test abnormal,10022891,Investigations,Inv,cholecalciferol,DB00169
,472180,DB00455,10048908,52,9349,18,5100,0.103458168,1.575880029,0.905626499,2.865584519,0.216219922,DB0045510048908_,1.531459234,0.454813865,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,loratadine,DB00455
,472477,DB00787,10061224,39,16961,27,17221,0.139485545,1.466562725,0.874724171,2.492388557,0.26909193,DB0078710061224_,1.31270221,0.38292138,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,acyclovir,DB00787
,472510,DB09037,10047895,52,2474,58,2777,1,1.006354987,0.675758109,1.495334183,1,DB0903710047895_,0,0.006334879,NA,10047895,Weight decreased,10022891,Investigations,Inv,pembrolizumab,DB09037
,472741,DB09122,10033371,50,1208,13,324,1,1.031576052,0.543875,2.096354441,1,DB0912210033371_,0,0.031087781,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,peginterferon beta-1a,DB09122
,472843,DB00264,10061599,41,29566,13,24879,0.00145815,2.653744932,1.393622134,5.398629453,0.007513717,DB0026410061599_,4.891025002,0.975971824,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,473186,DB01017,10028813,76,1393,29,872,0.030325495,1.640195046,1.046593383,2.633007897,0.085388928,DB0101710028813_,2.46053884,0.494815165,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,minocycline,DB01017
,473237,DB06228,10003662,38,15874,36,16040,0.816596141,1.066622007,0.65775105,1.732547021,0.901820493,DB0622810003662_,0.103339788,0.064496651,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,rivaroxaban,DB06228
,473273,DB01065,10010144,117,4214,25,3026,1.40128519181889e-09,3.360115883,2.161203035,5.417485924,3.7777211555856e-08,DB0106510010144_,17.09155979,1.211975462,female,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,melatonin,DB01065
,473414,DB00343,10023232,87,8649,28,5067,0.004788079,1.820240146,1.175071394,2.89942558,0.019757402,DB0034310023232_,3.924227088,0.598968441,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,diltiazem,DB00343
,473632,DB00999,10016326,44,21386,10,12229,0.006588778,2.515956853,1.246959266,5.608756236,0.025513559,DB0099910016326_,3.668545261,0.92265319,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,473707,DB01076,10038540,14,25733,46,25537,2.55324259210325e-05,0.302008184,0.153318304,0.559327841,0.000245922,DB0107610038540_,8.310498116,-1.197301161,male,10038540,Renal tubular necrosis,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,473844,DB00443,10013573,49,2097,19,1171,0.201767407,1.439978671,0.827842819,2.603141817,0.351164131,DB0044310013573_,1.046501556,0.364628302,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,betamethasone,DB00443
,473846,DB11750,10013573,50,2450,23,1490,0.329535571,1.322005353,0.788051194,2.280060443,0.498207896,DB1175010013573_,0.696737827,0.279149791,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,clobetasol,DB11750
,473869,DB00706,10016807,6,1069,89,15836,1,0.998686237,0.356124302,2.268400904,1,DB0070610016807_,0,-0.001314627,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,tamsulosin,DB00706
,473873,DB01306,10016807,33,4175,30,3836,1,1.010682015,0.596341057,1.719233194,1,DB0130610016807_,0,0.010625365,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,insulin aspart,DB01306
,474022,DB00727,10047289,14,3829,38,4135,0.003064088,0.397930777,0.198832593,0.752718305,0.013762738,DB0072710047289_,4.285790488,-0.921477216,NA,10047289,Ventricular extrasystoles,10007541,Cardiac disorders,Card,nitroglycerin,DB00727
,474035,DB00443,10047895,39,2107,36,1154,0.02799607,0.593410249,0.365208095,0.966584583,0.080212791,DB0044310047895_,2.523072283,-0.5218693,NA,10047895,Weight decreased,10022891,Investigations,Inv,betamethasone,DB00443
,474123,DB00047,10069868,108,9177,90,8428,0.520156623,1.10203123,0.824022198,1.476834128,0.679255204,DB0004710069868_,0.38675837,0.09715505,NA,10069868,Device issue,10077536,Product issues,Prod,insulin glargine,DB00047
,474217,DB05676,10012110,34,47095,21,25308,0.671613262,0.870054348,0.490497839,1.577823032,0.800757065,DB0567610012110_,0.222197668,-0.139199601,NA,10012110,Defaecation urgency,10017947,Gastrointestinal disorders,Gastr,apremilast,DB05676
,474354,DB00381,10023424,52,29308,23,22864,0.026289871,1.763739148,1.060153441,3.020615232,0.07640748,DB0038110023424_,2.571674683,0.567436071,NA,10023424,Kidney infection,10021881,Infections and infestations,Infec,amlodipine,DB00381
,474846,DB00281,10017413,32,11426,18,5653,0.654114876,0.879566202,0.478550881,1.665881927,0.787983662,DB0028110017413_,0.238277923,-0.128326446,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,lidocaine,DB00281
,474870,DB00787,10017626,27,16973,32,17216,0.603173499,0.855834506,0.493042323,1.475253902,0.746917473,DB0078710017626_,0.291800578,-0.155678256,NA,10017626,Gallbladder disorder,10019805,Hepatobiliary disorders,Hepat,acyclovir,DB00787
,474909,DB00836,10003445,31,5504,20,4055,0.672822448,1.141895453,0.629443173,2.117254228,0.801411037,DB0083610003445_,0.221381309,0.13268956,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,474925,DB00836,10010264,65,5470,25,4050,0.005093301,1.924910558,1.194350345,3.19298502,0.020761017,DB0083610010264_,3.874678232,0.654879503,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,475079,DB09146,10037844,48,740,21,406,0.438000089,1.25379314,0.72458767,2.237437261,0.606433266,DB0914610037844_,0.500160588,0.226173468,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,iron sucrose,DB09146
,475184,DB00557,10014387,62,5925,32,3035,1,0.992456875,0.636203953,1.575390862,1,DB0055710014387_,0,-0.007571719,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,hydroxyzine,DB00557
,475248,DB01104,10065154,95,15368,29,7257,0.042333534,1.546883869,1.010206191,2.43499584,0.110363198,DB0110410065154_,2.203978556,0.4362425,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,sertraline,DB01104
,475402,DB00537,10065154,40,7517,20,4278,0.688057986,1.138228715,0.64890274,2.058017554,0.811923868,DB0053710065154_,0.208348701,0.129473296,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,ciprofloxacin,DB00537
,475403,DB00959,10065154,37,8041,16,4986,0.258572786,1.433878789,0.77728989,2.763874065,0.419632987,DB0095910065154_,0.868374791,0.360383212,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,methylprednisolone,DB00959
,475449,DB01104,10016288,39,15424,25,7261,0.229349038,0.73437381,0.432997571,1.267199641,0.3851362,DB0110410016288_,0.954158241,-0.308737102,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,sertraline,DB01104
,475541,DB01267,10016322,26,2826,30,3685,0.685711985,1.13007853,0.640425451,1.981907095,0.810264988,DB0126710016322_,0.210393939,0.122287126,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,paliperidone,DB01267
,475768,DB05676,10061520,49,47080,14,25315,0.034485518,1.881940342,1.022215936,3.69184107,0.094382741,DB0567610061520_,2.360397056,0.632303342,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,475783,DB05676,10039906,34,47095,23,25306,0.406109589,0.794347135,0.45434137,1.412615543,0.575697905,DB0567610039906_,0.552172227,-0.230234716,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,475993,DB00008,10053762,38,1487,23,1653,0.027027606,1.836250022,1.060626098,3.244896854,0.078079945,DB0000810053762_,2.550022037,0.60772546,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,peginterferon alfa-2a,DB00008
,475995,DB01273,10053762,33,2007,20,1255,1,1.031756204,0.57187705,1.906410412,1,DB0127310053762_,0,0.031262403,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,varenicline,DB01273
,475999,DB09035,10037844,110,4616,150,6540,0.79897689,1.039015648,0.80245924,1.341760427,0.891407184,DB0903510037844_,0.114953959,0.038273773,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,nivolumab,DB09035
,476014,DB01611,10007882,67,11846,8,2353,0.21174866,1.663489453,0.796073077,4.015864043,0.363505438,DB0161110007882_,1.011961021,0.508917476,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,hydroxychloroquine,DB01611
,476123,DB00341,10001551,37,11368,29,5039,0.023138552,0.565585501,0.338051215,0.954609739,0.069239822,DB0034110001551_,2.670179126,-0.5698938,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,cetirizine,DB00341
,476242,DB11065,10008469,43,3143,30,2658,0.478639965,1.212113764,0.740611965,2.007247098,0.643910816,DB1106510008469_,0.440195047,0.192365748,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,pancrelipase amylase,DB11065
,476247,DB11065,10013573,73,3113,32,2656,0.001486457,1.946107607,1.263389073,3.058458327,0.007633391,DB1106510013573_,4.875223154,0.665831279,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pancrelipase amylase,DB11065
,476344,DB01115,10012378,42,3558,11,2257,0.006781292,2.421719157,1.222194621,5.226623187,0.026131983,DB0111510012378_,3.644595303,0.884477684,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,nifedipine,DB01115
,476382,DB00457,10016173,35,644,19,492,0.262448594,1.406927781,0.772203475,2.637522799,0.424233522,DB0045710016173_,0.857471216,0.341408448,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,prazosin,DB00457
,476404,DB00457,10019211,38,641,13,498,0.013223555,2.269492795,1.167329922,4.694906651,0.044478685,DB0045710019211_,3.112745193,0.819556368,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,prazosin,DB00457
,476797,DB09073,10013968,724,19536,26,764,0.768989775,1.088985209,0.731209577,1.689750257,0.873452361,DB0907310013968_,0.135301689,0.085246262,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,palbociclib,DB09073
,476890,DB09027,10000087,61,5118,47,7105,0.00312241,1.801625699,1.209228781,2.69902938,0.013979314,DB0902710000087_,4.270176583,0.588689423,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ledipasvir,DB09027
,476948,DB00588,10072878,36,16488,15,8453,0.556045179,1.230378718,0.656606444,2.420310993,0.709463013,DB0058810072878_,0.343246915,0.207322023,NA,10072878,Device use error,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,476993,DB08932,10060795,41,19402,15,6582,0.760460154,0.927260727,0.502133018,1.804704596,0.866887637,DB0893210060795_,0.14284591,-0.075520494,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,macitentan,DB08932
,477178,DB05676,10061224,36,47093,15,25314,0.464430079,1.290104713,0.688743011,2.536854756,0.631517272,DB0567610061224_,0.459629987,0.254723388,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,477354,DB09027,10003549,67,5112,91,7061,0.935447052,1.016974675,0.728923331,1.412775378,0.975645813,DB0902710003549_,0.024655655,0.016832216,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,477643,DB09073,10003549,847,19413,18,772,0.005967849,1.871307821,1.168637074,3.190629553,0.023563903,DB0907310003549_,3.748039258,0.626637556,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,palbociclib,DB09073
,477899,DB00190,10005746,19,3278,46,4628,0.057056616,0.583188587,0.322046828,1.017349265,0.137892447,DB0019010005746_,1.981281266,-0.539244669,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,carbidopa,DB00190
,477921,DB01024,10025482,45,2166,17,2103,0.000747282,2.569710498,1.436718418,4.804902054,0.004322215,DB0102410025482_,5.443987188,0.943793246,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,mycophenolic acid,DB01024
,478192,DB00864,10060931,26,6843,83,8309,6.48299093593652e-06,0.380395469,0.234658677,0.597946281,7.42830936142508e-05,DB0086410060931_,9.507627174,-0.96654386,NA,10060931,Adenovirus infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,478235,DB00524,10005483,36,1541,34,1310,0.716280193,0.900136264,0.54403165,1.492089144,0.832169766,DB0052410005483_,0.183718813,-0.105209123,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,metolazone,DB00524
,478325,DB08910,10003285,69,16675,81,17407,0.51284818,0.889249896,0.635042922,1.242266404,0.672984419,DB0891010003285_,0.396033101,-0.117376985,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,pomalidomide,DB08910
,478394,DB09029,10013573,130,11214,62,7208,0.053545599,1.347717854,0.986952646,1.857304367,0.131647747,DB0902910013573_,2.027625506,0.298412684,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,secukinumab,DB09029
,478395,DB09029,10019211,279,11065,129,7141,0.001733563,1.395771667,1.126352402,1.737134274,0.008641442,DB0902910019211_,4.751185869,0.333447429,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,secukinumab,DB09029
,478552,DB00512,10014387,51,4686,22,5076,0.000221926,2.510892442,1.492969488,4.354567425,0.001572538,DB0051210014387_,6.455064249,0.920638244,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,vancomycin,DB00512
,478796,DB00836,10054112,39,5496,35,4040,0.409987437,0.819110994,0.504576343,1.334263815,0.579402268,DB0083610054112_,0.545758279,-0.19953568,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,loperamide,DB00836
,478834,DB09073,10047942,2743,17517,39,751,6.22401794651768e-15,3.015278023,2.17863705,4.285622443,3.76954635309256e-13,DB0907310047942_,28.60665155,1.103692039,female,10047942,White blood cell count decreased,10022891,Investigations,Inv,palbociclib,DB09073
,479859,DB00019,10029410,33,18979,31,9498,0.016107555,0.532725245,0.316096649,0.900024539,0.052099562,DB0001910029410_,2.954598733,-0.629749475,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,pegfilgrastim,DB00019
,480005,DB00836,10013786,46,5489,26,4049,0.338330789,1.305049447,0.788438041,2.203232871,0.507418966,DB0083610013786_,0.678418254,0.26624093,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,loperamide,DB00836
,480058,DB00425,10061309,30,12665,25,7459,0.20980977,0.706770599,0.401463307,1.254334615,0.360931301,DB0042510061309_,1.019067641,-0.347049137,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,zolpidem,DB00425
,480096,DB00043,10053762,184,6229,90,2210,0.01768271,0.725381426,0.557963181,0.948636451,0.056103457,DB0004310053762_,2.880557852,-0.321057657,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,omalizumab,DB00043
,480515,DB00316,10013050,40,65434,22,36931,1,1.026183935,0.595328202,1.813113377,1,DB0031610013050_,0,0.025847004,NA,10013050,Disability,10041244,Social circumstances,SocCi,acetaminophen,DB00316
,480691,DB00864,10020937,35,6834,29,8363,0.131264405,1.476865356,0.875978687,2.507431314,0.257570445,DB0086410020937_,1.356462023,0.389921839,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,tacrolimus,DB00864
,480981,DB00410,10037087,42,1563,22,987,0.518085451,1.205434539,0.698562499,2.134184556,0.677438866,DB0041010037087_,0.389435965,0.186840115,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,mupirocin,DB00410
,481180,DB00836,10013950,42,5493,22,4053,0.206355696,1.408569162,0.82050485,2.481723536,0.356885319,DB0083610013950_,1.030340785,0.34257441,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,loperamide,DB00836
,481247,DB00489,10048959,32,1051,18,1116,0.032174872,1.887180762,1.020664777,3.594208838,0.089484341,DB0048910048959_,2.413691634,0.635084055,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sotalol,DB00489
,481336,DB08906,10037087,55,2138,27,1131,0.81469754,1.077573732,0.663968645,1.787285274,0.90059403,DB0890610037087_,0.1047007,0.074711969,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone furoate,DB08906
,481385,DB00264,10029446,22,29585,40,24852,0.003185696,0.462014306,0.261440735,0.796515873,0.014209405,DB0026410029446_,4.253851225,-0.772159422,NA,10029446,Nocturia,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,481458,DB00999,10062352,48,21382,12,12227,0.007170406,2.287292152,1.196316874,4.731929794,0.027303218,DB0099910062352_,3.6007507,0.827368652,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,hydrochlorothiazide,DB00999
,481580,DB08906,10022437,33,2160,17,1141,1,1.025401647,0.552201092,1.971896066,1,DB0890610022437_,0,0.025084387,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,fluticasone furoate,DB08906
,481582,DB08906,10033371,85,2108,25,1133,0.007836561,1.827122092,1.150296232,2.997194826,0.029288212,DB0890610033371_,3.530570162,0.602742101,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,fluticasone furoate,DB08906
,481586,DB08906,10033425,41,2152,12,1146,0.079825119,1.819178047,0.933459061,3.818163653,0.178115726,DB0890610033425_,1.725321792,0.598384776,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone furoate,DB08906
,481913,DB00635,10058046,36,33017,20,23774,0.416631938,1.296089389,0.730232548,2.363648867,0.58584339,DB0063510058046_,0.534702777,0.259351569,NA,10058046,Post procedural complication,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,482159,DB01611,10071404,30,11883,37,2324,5.3770629131259e-13,0.158603784,0.094400767,0.264434575,2.49050394134827e-11,DB0161110071404_,24.41595095,-1.841346114,male,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxychloroquine,DB01611
,482429,DB01590,10038389,14,4724,38,2829,3.19070667353724e-07,0.22067707,0.110230698,0.417530908,5.16267928063566e-06,DB0159010038389_,12.17405487,-1.511054867,male,10038389,Renal cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,everolimus,DB01590
,482562,DB05679,10061623,32,6899,18,4891,0.47442136,1.260319034,0.685501561,2.387646484,0.640077413,DB0567910061623_,0.446166152,0.231364891,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,482620,DB00863,10006784,48,10625,18,5822,0.197214602,1.461176118,0.833558947,2.671635784,0.345666376,DB0086310006784_,1.062281201,0.379241672,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,ranitidine,DB00863
,482836,DB00612,10047700,37,1103,13,627,0.177820696,1.617489444,0.832723886,3.342394715,0.321094836,DB0061210047700_,1.136018759,0.480875221,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,bisoprolol,DB00612
,483296,DB00341,10014020,45,11360,7,5061,0.006159031,2.863810359,1.280849618,7.532214458,0.02416451,DB0034110014020_,3.722870256,1.052153031,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,cetirizine,DB00341
,483429,DB00947,10029354,206,2966,7,61,0.211277234,0.605359184,0.27200109,1.589047862,0.362873895,DB0094710029354_,1.013699901,-0.501933305,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,fulvestrant,DB00947
,483523,DB01006,10047942,676,5271,8,169,0.002341709,2.708956364,1.335511142,6.405833829,0.011060527,DB0100610047942_,4.504372679,0.996563455,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,letrozole,DB01006
,483524,DB01101,10047942,57,7532,24,3884,0.480197458,1.224653874,0.746596641,2.066933346,0.645015723,DB0110110047942_,0.438480585,0.202658252,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,capecitabine,DB01101
,483763,DB00404,10062519,42,19850,16,9846,0.405078237,1.30208728,0.71638806,2.482055592,0.574774972,DB0040410062519_,0.553776668,0.263968577,NA,10062519,Poor quality sleep,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,484483,DB01073,10013709,38,1027,53,1597,0.662519334,1.114868703,0.709507934,1.737219621,0.794254303,DB0107310013709_,0.230351588,0.108736643,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,fludarabine,DB01073
,485716,DB00115,10043417,44,18381,18,10454,0.290002423,1.390236785,0.786552221,2.55768715,0.455223272,DB0011510043417_,0.786967272,0.329474081,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,485723,DB01373,10043417,50,22670,9,7372,0.128264112,1.80648673,0.878976658,4.18063645,0.253176299,DB0137310043417_,1.373669201,0.591383926,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,486317,DB00203,10074414,159,13719,58,8880,0.000148938,1.774388316,1.304174725,2.443163712,0.001119325,DB0020310074414_,6.795029535,0.573455753,NA,10074414,Catheter management,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,486732,DB00921,10073954,80,5765,70,4833,0.804900831,0.958081593,0.684798375,1.343104204,0.894427482,DB0092110073954_,0.11157145,-0.042822335,NA,10073954,Intentional underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,buprenorphine,DB00921
,487286,DB01060,10042674,67,8520,35,5046,0.607588683,1.133754964,0.741336075,1.761174508,0.750474309,DB0106010042674_,0.28704986,0.125535101,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,487443,DB00374,10061225,49,17667,15,5709,1,1.055578705,0.58167782,2.028347478,1,DB0037410061225_,0,0.054089152,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,487556,DB01098,10038153,34,8115,26,7183,0.606152687,1.157493561,0.673595039,2.01075022,0.749175877,DB0109810038153_,0.288781507,0.146256944,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,rosuvastatin,DB01098
,487623,DB01175,10003246,40,10684,10,4882,0.093381397,1.827717643,0.897257381,4.102072017,0.200741886,DB0117510003246_,1.605735345,0.603067999,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,escitalopram,DB01175
,487696,DB00273,10038535,45,8436,6,2187,0.162466265,1.944207397,0.825445264,5.583927163,0.300607193,DB0027310038535_,1.201950873,0.664854386,NA,10038535,Renal tubular acidosis,10038359,Renal and urinary disorders,Renal,topiramate,DB00273
,488454,DB06262,10013950,29,3771,55,4259,0.027433923,0.595545296,0.36536142,0.952559951,0.078959833,DB0626210013950_,2.538815998,-0.51827783,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,droxidopa,DB06262
,488480,DB00820,10001949,32,11883,20,5796,0.378386213,0.780445524,0.432428514,1.441151145,0.548375234,DB0082010001949_,0.600795493,-0.247890338,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,tadalafil,DB00820
,488482,DB08932,10001949,61,19382,16,6581,0.431211881,1.29447805,0.736370643,2.407274317,0.599653112,DB0893210001949_,0.511403938,0.258107564,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,488557,DB00996,10036495,62,38891,17,22408,0.004872451,2.101316434,1.212649015,3.835236487,0.020042624,DB0099610036495_,3.909894054,0.742564022,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,488601,DB09037,10029354,35,2491,24,2811,0.066347748,1.645505088,0.948384146,2.900121245,0.154797671,DB0903710029354_,1.865636363,0.498047381,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,pembrolizumab,DB09037
,488608,DB06262,10016322,160,3640,106,4208,1.10856404449845e-05,1.744830793,1.350841938,2.261374254,0.000118618,DB0626210016322_,9.039599079,0.556657584,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,488645,DB00126,10046543,38,10133,14,5931,0.151293582,1.588669771,0.840600108,3.177058438,0.28565541,DB0012610046543_,1.252969054,0.462897044,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,ascorbic acid,DB00126
,488648,DB00126,10074903,40,10131,12,5933,0.043329435,1.952019177,1.003004359,4.090376734,0.112330032,DB0012610074903_,2.186314027,0.668864312,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,ascorbic acid,DB00126
,488652,DB00879,10003239,17,1760,41,3671,0.674100989,0.864871966,0.459313796,1.561411046,0.80233402,DB0087910003239_,0.220230274,-0.145173799,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,emtricitabine,DB00879
,488762,DB01060,10017885,49,8538,34,5047,0.495100852,0.851927319,0.538151806,1.36277524,0.657500651,DB0106010017885_,0.419309524,-0.160254062,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,amoxicillin,DB01060
,488797,DB00537,10054112,87,7470,48,4250,0.928335463,1.031206978,0.715265645,1.502210756,0.970147351,DB0053710054112_,0.030307311,0.030729939,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,ciprofloxacin,DB00537
,488798,DB00586,10054112,51,7058,27,2778,0.209311145,0.74347984,0.456530633,1.235768149,0.360368341,DB0058610054112_,1.020628602,-0.296413628,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,diclofenac,DB00586
,488908,DB06228,10027599,71,15841,13,16063,3.65845607230946e-11,5.537659316,3.039004115,10.90831889,1.28473637756385e-09,DB0622810027599_,20.47271229,1.711571905,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,rivaroxaban,DB06228
,489202,DB01222,10020642,48,9226,25,5380,0.715848911,1.119627758,0.675884826,1.897225669,0.831856904,DB0122210020642_,0.184094843,0.112996271,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,budesonide,DB01222
,489359,DB00688,10017944,46,6444,28,5350,0.200190291,1.363911554,0.833314447,2.269208648,0.349205416,DB0068810017944_,1.052094945,0.310356714,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,mycophenolate mofetil,DB00688
,489689,DB08895,10076309,358,27756,116,6530,0.003883302,0.726082672,0.586233711,0.904727809,0.016651322,DB0889510076309_,4.095265666,-0.320091397,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,489727,DB00557,10019063,35,5952,25,3042,0.21845506,0.715524828,0.415356453,1.249696053,0.37166842,DB0055710019063_,0.989753166,-0.33473898,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,hydroxyzine,DB00557
,489728,DB00814,10019063,41,8246,36,3379,0.001453314,0.466711177,0.290421463,0.753053609,0.007493939,DB0081410019063_,4.893660671,-0.762044677,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,meloxicam,DB00814
,489807,DB00956,10028391,45,5769,17,3450,0.114736763,1.582930567,0.886728188,2.954975158,0.233235823,DB0095610028391_,1.45570522,0.459277918,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,hydrocodone,DB00956
,489886,DB08931,10061024,71,6506,32,2414,0.372937085,0.823238539,0.533636951,1.295301895,0.542627581,DB0893110061024_,0.611332049,-0.194509279,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,riociguat,DB08931
,490085,DB08931,10022595,42,6535,15,2431,1,1.041554305,0.564689383,2.025897365,1,DB0893110022595_,0,0.040714121,NA,10022595,International normalised ratio increased,10022891,Investigations,Inv,riociguat,DB08931
,490146,DB06262,10007559,14,3786,39,4275,0.003349408,0.405398989,0.202979006,0.76461814,0.014780376,DB0626210007559_,4.214454922,-0.902883538,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,droxidopa,DB06262
,490542,DB06262,10020100,32,3768,18,4296,0.015671461,2.026699939,1.101765751,3.841684793,0.05102178,DB0626210020100_,2.97550268,0.706408825,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,droxidopa,DB06262
,490544,DB00028,10061822,36,13422,14,5601,0.877952491,1.073052384,0.564287427,2.155574865,0.948285522,DB0002810061822_,0.053099639,0.070507283,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,490548,DB06262,10037660,25,3775,39,4275,0.257604193,0.725959551,0.420208302,1.232862499,0.418448613,DB0626210037660_,0.871201186,-0.320260981,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,491056,DB13961,10043882,34,9423,18,6396,0.479497112,1.282091074,0.703329813,2.413538561,0.644498431,DB1396110043882_,0.439282891,0.248492396,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,fish oil,DB13961
,491227,DB01229,10028533,42,5699,10,2699,0.052143412,1.988945507,0.980150073,4.452506027,0.129051323,DB0122910028533_,2.047545097,0.687604602,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,paclitaxel,DB01229
,491463,DB08907,10064355,37,4216,36,3874,0.815131494,0.944385469,0.579229052,1.54113941,0.900803434,DB0890710064355_,0.10446821,-0.05722086,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,canagliflozin,DB08907
,491622,DB01377,10046306,41,3755,10,2660,0.001455385,2.903939571,1.427370348,6.51272716,0.007501677,DB0137710046306_,4.892628717,1.066068288,female,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,magnesium oxide,DB01377
,491683,DB01394,10010144,24,1416,59,1944,0.017624755,0.558551549,0.330554583,0.91693026,0.055977124,DB0139410010144_,2.882812164,-0.582408366,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,colchicine,DB01394
,491694,DB00433,10061024,34,7622,24,5996,0.791218107,1.114405509,0.640965494,1.966564249,0.886967392,DB0043310061024_,0.119947059,0.108321087,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,prochlorperazine,DB00433
,491752,DB01238,10069339,46,5204,26,3476,0.547050264,1.181700377,0.713777903,1.995407542,0.701728792,DB0123810069339_,0.354208286,0.166954398,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,aripiprazole,DB01238
,492103,DB00531,10073755,98,7154,56,6460,0.007215276,1.58017762,1.124468515,2.239238715,0.027422431,DB0053110073755_,3.596393947,0.457537258,NA,10073755,Pneumocystis jirovecii pneumonia,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,492158,DB05676,10040943,31,47098,22,25307,0.31644646,0.757167728,0.424356704,1.372790241,0.484143452,DB0567610040943_,0.725374029,-0.278170481,NA,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,492189,DB00820,10016326,49,11866,14,5802,0.080642802,1.71131326,0.928801781,3.359205579,0.179437573,DB0082010016326_,1.717927916,0.537261064,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,492306,DB00213,10037162,68,18827,32,13389,0.053922745,1.511193632,0.97833639,2.379259058,0.132364526,DB0021310037162_,2.022195605,0.412899824,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,pantoprazole,DB00213
,492360,DB00972,10003239,66,2438,21,1158,0.13024456,1.492642243,0.896456715,2.581784502,0.25606629,DB0097210003239_,1.362318921,0.400547867,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,azelastine,DB00972
,492368,DB00471,10031161,74,14115,9,5456,0.000302079,3.178312651,1.585211493,7.228188595,0.002028913,DB0047110031161_,6.200254942,1.156350443,female,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,montelukast,DB00471
,492468,DB05676,10074903,80,47049,35,25294,0.329140806,1.228780038,0.81607684,1.884665216,0.497768538,DB0567610074903_,0.697620093,0.206021838,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,apremilast,DB05676
,492640,DB08931,10003246,38,6539,13,2433,0.8754745,1.087593795,0.565557022,2.229031399,0.94649511,DB0893110003246_,0.054989475,0.083967729,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,riociguat,DB08931
,492692,DB00454,10037087,48,1919,8,593,0.112108638,1.853623576,0.862877795,4.56368519,0.22923186,DB0045410037087_,1.4730213,0.617142413,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,meperidine,DB00454
,492763,DB00331,10075192,24,24922,36,20716,0.026970733,0.55417018,0.316150269,0.955160141,0.077951037,DB0033110075192_,2.551674375,-0.590283455,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,metformin,DB00331
,492879,DB00273,10066901,38,8443,18,2175,0.044573112,0.543887378,0.302190761,1.01448772,0.11472257,DB0027310066901_,2.165238499,-0.609013079,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,topiramate,DB00273
,493016,DB06605,10022086,47,14026,14,13019,8.61047616766424e-05,3.115766541,1.685579519,6.131627178,0.000702217,DB0660510022086_,7.261268754,1.136475203,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,493051,DB08932,10037368,79,19364,27,6570,1,0.992735837,0.633478665,1.60043107,1,DB0893210037368_,0,-0.007290675,NA,10037368,Pulmonary congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,493159,DB06674,10020751,48,4458,12,1478,0.45401458,1.326080768,0.691584542,2.750402133,0.621518318,DB0667410020751_,0.475589894,0.282227801,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,golimumab,DB06674
,493308,DB08815,10016322,30,1424,20,683,0.28553525,0.719545729,0.392090877,1.347335951,0.450160087,DB0881510016322_,0.798152011,-0.329135199,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,lurasidone,DB08815
,493344,DB08935,10021097,19,513,34,779,0.667755087,0.848705669,0.452024479,1.54998278,0.798178374,DB0893510021097_,0.22542318,-0.164042833,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,obinutuzumab,DB08935
,493374,DB00537,10058080,22,7535,30,4268,0.002073514,0.415406505,0.228013351,0.745737366,0.010020651,DB0053710058080_,4.60310719,-0.878497708,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,493523,DB00169,10073133,18,38673,32,18143,4.53886164873891e-06,0.263897428,0.139430091,0.484688046,5.4377383061578e-05,DB0016910073133_,9.819562243,-1.332194782,male,10073133,Plasma cell myeloma recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cholecalciferol,DB00169
,493545,DB00482,10048334,53,8206,9,3062,0.03040814,2.197300989,1.072748243,5.073201562,0.085557479,DB0048210048334_,2.458566858,0.787229784,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,celecoxib,DB00482
,493916,DB00165,10028810,36,2109,18,1348,0.482231135,1.278234254,0.703773324,2.401429972,0.6466899,DB0016510028810_,0.435888389,0.245479636,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,pyridoxine,DB00165
,493962,DB00668,10047895,60,10031,26,4277,1,0.983950559,0.610490626,1.626872369,1,DB0066810047895_,0,-0.016179628,NA,10047895,Weight decreased,10022891,Investigations,Inv,epinephrine,DB00668
,494253,DB01020,10048959,43,1770,28,1850,0.055410649,1.604909538,0.969616157,2.695556232,0.135014499,DB0102010048959_,2.002373103,0.473067392,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,isosorbide mononitrate,DB01020
,494316,DB00787,10018627,14,16986,51,17197,4.54467897504124e-06,0.277952006,0.142019279,0.510023358,5.44222719175212e-05,DB0078710018627_,9.818737078,-1.280306821,male,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,acyclovir,DB00787
,494381,DB00924,10024264,50,10112,13,4238,0.129772114,1.611913087,0.861534368,3.238181176,0.255328419,DB0092410024264_,1.365204645,0.477421726,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,cyclobenzaprine,DB00924
,494397,DB00480,10000125,22,67406,32,67630,0.220273561,0.689789786,0.381822678,1.224725709,0.373782476,DB0048010000125_,0.984081266,-0.371368386,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,lenalidomide,DB00480
,494434,DB06605,10047924,46,14027,24,13009,0.02261534,1.777521569,1.062081269,3.046748613,0.067990936,DB0660510047924_,2.688380881,0.575220017,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,494484,DB01048,10069339,16,449,42,1093,0.883510389,0.927395799,0.481465997,1.705261566,0.951297336,DB0104810069339_,0.049928609,-0.075374837,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,abacavir,DB01048
,494600,DB08889,10048959,36,3129,42,3843,0.820114459,1.052756386,0.6535739,1.687909231,0.904243317,DB0888910048959_,0.100656799,0.051411854,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,carfilzomib,DB08889
,494698,DB01098,10052904,42,8107,31,7178,0.481721153,1.199569503,0.735502743,1.976001944,0.646283719,DB0109810052904_,0.436516679,0.181962745,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,494713,DB01285,10022052,43,1233,11,598,0.075189221,1.895326107,0.952655879,4.105590649,0.17016951,DB0128510022052_,1.770960223,0.639390912,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,corticotropin,DB01285
,494813,DB00175,10039906,49,8082,27,6079,0.203167323,1.365010327,0.835524821,2.27399247,0.352817988,DB0017510039906_,1.041802968,0.311161994,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,pravastatin,DB00175
,494920,DB00410,10048959,40,1565,20,989,0.424015146,1.263773734,0.716703739,2.295987257,0.592800282,DB0041010048959_,0.522897729,0.234102272,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,mupirocin,DB00410
,495050,DB06655,10000059,47,3641,31,2088,0.555310716,0.869478843,0.539013662,1.420483268,0.708749529,DB0665510000059_,0.344253088,-0.139861277,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,liraglutide,DB06655
,495168,DB01015,10007515,26,9861,48,9333,0.006959428,0.512684662,0.305065638,0.843832556,0.026677637,DB0101510007515_,3.623929614,-0.668094316,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,sulfamethoxazole,DB01015
,495276,DB08868,10019303,51,9151,8,2503,0.15441911,1.743597482,0.819980656,4.26020615,0.290035822,DB0886810019303_,1.237750838,0.555950497,NA,10019303,Heart rate increased,10022891,Investigations,Inv,fingolimod,DB08868
,495397,DB00152,10069339,20,811,37,827,0.042361919,0.551396572,0.300499227,0.98451545,0.110404348,DB0015210069339_,2.203605764,-0.595300997,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,thiamine,DB00152
,495398,DB00571,10069339,30,5093,33,2576,0.002897069,0.459853104,0.270255401,0.779694126,0.013135276,DB0057110069339_,4.332453849,-0.776848181,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,propranolol,DB00571
,495494,DB00555,10013036,39,7008,31,3455,0.055271018,0.620251743,0.376422631,1.030095259,0.134817995,DB0055510013036_,2.003829597,-0.477629847,NA,10013036,Diplopia,10015919,Eye disorders,Eye,lamotrigine,DB00555
,495598,DB00668,10020642,48,10043,23,4280,0.696711124,0.889407529,0.529702076,1.534073948,0.817528949,DB0066810020642_,0.201468965,-0.117199736,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,epinephrine,DB00668
,495612,DB00557,10047513,74,5913,19,3048,0.005644541,2.007500985,1.197093387,3.527062948,0.022549854,DB0055710047513_,3.792026694,0.696890658,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,hydroxyzine,DB00557
,495772,DB01015,10066901,39,9848,31,9350,0.474924468,1.194433682,0.725567559,1.981686681,0.640551589,DB0101510066901_,0.445425617,0.177672167,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,495961,DB01229,10007515,34,5707,24,2685,0.157035226,0.666529958,0.382943331,1.177343797,0.293538683,DB0122910007515_,1.225745849,-0.405670192,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,paclitaxel,DB01229
,495965,DB01281,10042128,71,8861,8,1790,0.130371791,1.792737075,0.86012757,4.320302326,0.256268511,DB0128110042128_,1.361529515,0.583743544,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,abatacept,DB01281
,496004,DB00829,10035669,34,8018,23,4431,0.48888937,0.81695915,0.466727211,1.454466848,0.652373697,DB0082910035669_,0.427137727,-0.202166186,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,diazepam,DB00829
,496052,DB01234,10067973,24,31601,30,32858,0.586425143,0.831825131,0.465260264,1.47212491,0.733659442,DB0123410067973_,0.309710333,-0.18413304,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,dexamethasone,DB01234
,496059,DB00704,10013573,177,4179,159,5035,0.008727964,1.341177776,1.072123188,1.678955984,0.031942987,DB0070410013573_,3.443802633,0.293548165,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,naltrexone,DB00704
,496062,DB00704,10041349,93,4263,107,5087,0.829717006,1.037170981,0.77454893,1.386714319,0.910667119,DB0070410041349_,0.09357785,0.036496796,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,naltrexone,DB00704
,496162,DB01065,10042772,39,4292,27,3024,1,1.017705875,0.6058274,1.732892631,1,DB0106510042772_,0,0.017550952,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,melatonin,DB01065
,496395,DB06317,10016256,43,560,43,677,0.433680673,1.208749882,0.761266662,1.919394417,0.602181537,DB0631710016256_,0.507196323,0.18958667,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,elotuzumab,DB06317
,496430,DB00999,10020947,47,21383,9,12230,0.001205956,2.986759694,1.44640592,6.933858226,0.006429725,DB0099910020947_,5.046823503,1.094189086,female,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,496685,DB09033,10028411,30,2594,32,1637,0.048223274,0.591726504,0.345896966,1.009709175,0.121762608,DB0903310028411_,2.105681969,-0.524710737,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,vedolizumab,DB09033
,497019,DB05676,10011906,286,46843,295,25034,6.03700209642737e-15,0.518107371,0.438453647,0.612172174,3.66049827230896e-13,DB0567610011906_,28.63600693,-0.657572779,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,497080,DB00472,10013786,39,10720,12,4300,0.534767219,1.303589353,0.667937053,2.737591424,0.691356707,DB0047210013786_,0.36909937,0.2651215,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,fluoxetine,DB00472
,497373,DB09027,10010264,43,5136,60,7092,1,0.989603289,0.651818219,1.491252315,1,DB0902710010264_,0,-0.010451134,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,497432,DB00537,10022000,53,7504,26,4272,0.559788694,1.160501283,0.711688364,1.936347028,0.712458338,DB0053710022000_,0.339033842,0.148852053,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,497642,DB00423,10048959,33,2434,18,1022,0.358901693,0.769828827,0.418853182,1.459285092,0.528648417,DB0042310048959_,0.637431687,-0.261587092,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,methocarbamol,DB00423
,497905,DB00540,10007515,58,2425,22,1069,0.624051697,1.162117641,0.69619012,2.004889991,0.763969953,DB0054010007515_,0.26922682,0.150243893,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,nortriptyline,DB00540
,498051,DB00695,10005169,56,27993,21,20507,0.007709156,1.953498221,1.163834695,3.397749636,0.028925152,DB0069510005169_,3.543043736,0.669621725,NA,10005169,Blindness,10015919,Eye disorders,Eye,furosemide,DB00695
,498072,DB00230,10047461,50,19624,10,8641,0.017222707,2.201589325,1.102786198,4.871994043,0.054953385,DB0023010047461_,2.901269999,0.78917952,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,pregabalin,DB00230
,498133,DB09140,10047513,33,3708,17,1781,0.879528534,0.932385274,0.503068907,1.7898605,0.949440749,DB0914010047513_,0.051882153,-0.070009165,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,oxygen,DB09140
,498135,DB04951,10061428,128,1754,207,2850,1,1.004742324,0.793075318,1.269107878,1,DB0495110061428_,0,0.004731114,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,pirfenidone,DB04951
,498532,DB00635,10034960,45,33008,19,23775,0.0566405,1.705905724,0.977515004,3.089279894,0.137197212,DB0063510034960_,1.986335884,0.534096186,NA,10034960,Photophobia,10015919,Eye disorders,Eye,prednisone,DB00635
,498682,DB00678,10041232,31,15568,21,10703,1,1.014880984,0.564490189,1.859251715,1,DB0067810041232_,0,0.014771349,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,losartan,DB00678
,498944,DB09027,10033425,54,5125,46,7106,0.018851441,1.627571054,1.076058943,2.470878497,0.058992813,DB0902710033425_,2.830339657,0.487088752,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ledipasvir,DB09027
,498948,DB09027,10048959,41,5138,32,7120,0.016934986,1.775371084,1.089368762,2.916913081,0.054239105,DB0902710048959_,2.914353134,0.574009463,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,499159,DB00761,10056819,62,15245,24,8601,0.143005962,1.457455984,0.895837717,2.443744769,0.274063047,DB0076110056819_,1.294397101,0.376692439,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,potassium chloride,DB00761
,499166,DB06282,10012735,75,1465,27,506,0.907510128,0.959440614,0.602590692,1.568490625,0.958758188,DB0628210012735_,0.042116386,-0.041404858,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,levocetirizine,DB06282
,499750,DB00727,10029354,21,3822,34,4139,0.175450577,0.668910632,0.368223,1.188533828,0.317942121,DB0072710029354_,1.145885921,-0.402104813,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,nitroglycerin,DB00727
,499868,DB00051,10024384,67,25664,15,11405,0.015935551,1.984940717,1.121422641,3.743335475,0.051677607,DB0005110024384_,2.962730715,0.685589048,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,adalimumab,DB00051
,500075,DB00213,10046543,46,18849,23,13398,0.179957134,1.421597687,0.84368092,2.458467713,0.323795959,DB0021310046543_,1.127641717,0.351781371,NA,10046543,Urinary incontinence,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,500270,DB00571,10034568,42,5081,10,2599,0.026966438,2.148173244,1.058478487,4.809813412,0.077947196,DB0057110034568_,2.551723654,0.764617827,NA,10034568,Peripheral coldness,10047065,Vascular disorders,Vasc,propranolol,DB00571
,500509,DB00480,10028116,36,67392,21,67641,0.047528589,1.720602062,0.977611471,3.102468014,0.120448617,DB0048010028116_,2.116532032,0.542674266,NA,10028116,Mucosal inflammation,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,500690,DB00761,10007556,43,15264,22,8603,0.796323311,1.101616202,0.644096537,1.93510747,0.889730643,DB0076110007556_,0.116836511,0.096778376,NA,10007556,Cardiac failure acute,10007541,Cardiac disorders,Card,potassium chloride,DB00761
,500716,DB08815,10012378,58,1396,22,681,0.394790933,1.285973216,0.767501002,2.226001835,0.564682319,DB0881510012378_,0.571491974,0.251515798,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,lurasidone,DB08815
,500731,DB01068,10061225,35,13728,17,6823,1,1.023281246,0.557646788,1.949230487,1,DB0106810061225_,0,0.023014372,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,501132,DB00787,10051792,47,16953,52,17196,0.688227838,0.916823114,0.604199367,1.387900415,0.812014935,DB0078710051792_,0.208236546,-0.086840722,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,501163,DB00688,10037423,39,6451,19,5359,0.063647072,1.705092323,0.960554036,3.12798824,0.15004155,DB0068810037423_,1.896843022,0.533619258,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolate mofetil,DB00688
,501188,DB00555,10028810,45,7002,16,3470,0.277579538,1.393765391,0.771501114,2.64567856,0.44120325,DB0055510028810_,0.818249625,0.332008999,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,lamotrigine,DB00555
,501259,DB01195,10069339,41,1198,12,732,0.0299836,2.086951214,1.067514468,4.391660639,0.084680232,DB0119510069339_,2.468873096,0.735704252,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,flecainide,DB01195
,501293,DB06605,10005364,14,14059,36,12997,0.000921785,0.359525422,0.179053328,0.683432225,0.005154585,DB0660510005364_,5.267868617,-1.022970389,male,10005364,Blood bilirubin increased,10022891,Investigations,Inv,apixaban,DB06605
,501296,DB01012,10008190,67,10565,32,8653,0.011279189,1.714783802,1.108265572,2.703795013,0.039174614,DB0101210008190_,3.239726349,0.53928701,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,cinacalcet,DB01012
,501392,DB00254,10037153,54,5881,32,3356,0.910423516,0.963005919,0.609328637,1.544421526,0.95959909,DB0025410037153_,0.041239696,-0.037695721,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,doxycycline,DB00254
,501678,DB00916,10017955,26,5297,34,2397,6.08989865673883e-05,0.346097744,0.198958341,0.595575657,0.000522431,DB0091610017955_,7.557016842,-1.061034046,male,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,metronidazole,DB00916
,501779,DB01377,10016807,42,3754,24,2646,0.452531667,1.233444598,0.727873734,2.134942111,0.620166573,DB0137710016807_,0.477767172,0.209810742,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,magnesium oxide,DB01377
,502062,DB00455,10060800,64,9337,12,5106,0.000249411,2.916387475,1.558046809,5.942591806,0.001731628,DB0045510060800_,6.358693498,1.070345684,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,loratadine,DB00455
,502224,DB10631,10028813,74,1222,7,204,0.187559206,1.764223889,0.799351065,4.60434301,0.333502028,DB1063110028813_,1.098106334,0.567710871,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,cranberry,DB10631
,502291,DB00404,10014020,44,19848,8,9854,0.004962458,2.730524291,1.270850043,6.718083954,0.020341243,DB0040410014020_,3.895104788,1.004493639,female,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,alprazolam,DB00404
,502467,DB01234,10061603,47,31578,23,32865,0.002614944,2.126725817,1.265426798,3.670503989,0.012086243,DB0123410061603_,4.41568738,0.754583622,NA,10061603,Respiratory syncytial virus infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,502659,DB08932,10013911,49,19394,14,6583,0.664310795,1.188010158,0.644948123,2.331678281,0.795635261,DB0893210013911_,0.228614413,0.172279771,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,502744,DB01075,10040984,42,19906,16,11081,0.218540989,1.461232081,0.804017712,2.78549109,0.371730597,DB0107510040984_,0.989585889,0.379279971,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,diphenhydramine,DB01075
,502796,DB00904,10037153,91,22978,24,14432,6.98641144094769e-05,2.381409519,1.504303169,3.907492302,0.000586047,DB0090410037153_,7.442110582,0.867692547,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,ondansetron,DB00904
,502885,DB00455,10061822,40,9361,22,5096,1,0.989791045,0.573542521,1.750586843,1,DB0045510061822_,0,-0.010261424,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,503082,DB00316,10043709,53,65421,15,36938,0.016073137,1.994976122,1.107676,3.811471532,0.052007436,DB0031610043709_,2.956368563,0.690632081,NA,10043709,Thyroid disorder,10014698,Endocrine disorders,Endo,acetaminophen,DB00316
,503114,DB00381,10021114,35,29325,21,22866,0.419050985,1.299566162,0.735476572,2.350133036,0.588112293,DB0038110021114_,0.530837374,0.262030487,NA,10021114,Hypothyroidism,10014698,Endocrine disorders,Endo,amlodipine,DB00381
,503211,DB00497,10011781,49,19218,15,16360,0.000235002,2.780686221,1.532929285,5.341926578,0.001647865,DB0049710011781_,6.408274885,1.022697739,female,10011781,Cystitis,10021881,Infections and infestations,Infec,oxycodone,DB00497
,503387,DB01068,10055798,41,13722,20,6820,1,1.018886784,0.582847223,1.837181544,1,DB0106810055798_,0,0.018710643,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,clonazepam,DB01068
,503505,DB00190,10057362,76,3221,105,4569,0.878816104,1.026734766,0.751325458,1.397616649,0.949052042,DB0019010057362_,0.052291643,0.026383637,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,carbidopa,DB00190
,503554,DB13867,10015150,37,4513,18,2536,0.673979819,1.155084345,0.639621891,2.15996947,0.802280622,DB1386710015150_,0.22029683,0.144173367,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone,DB13867
,503555,DB13867,10018884,51,4499,28,2526,1,1.022653376,0.63098332,1.688955059,1,DB1386710018884_,0,0.022400598,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,fluticasone,DB13867
,503829,DB00924,10065154,83,10079,26,4225,0.207318475,1.338110379,0.850966772,2.169785865,0.358039823,DB0092410065154_,1.027111061,0.291258454,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,cyclobenzaprine,DB00924
,503882,DB00737,10012378,50,2751,12,920,0.374793489,1.393291269,0.727636643,2.887593839,0.544637122,DB0073710012378_,0.607635538,0.331668768,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,meclizine,DB00737
,504106,DB00704,10013709,199,4157,224,4970,0.549452414,1.062105285,0.869075711,1.297306433,0.703767108,DB0070410013709_,0.35130779,0.060253057,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,504124,DB00355,10012735,33,1760,19,1244,0.570432484,1.227550343,0.674271071,2.296350958,0.720960612,DB0035510012735_,0.327170772,0.205020593,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,aztreonam,DB00355
,504173,DB00624,10069327,11,551,54,4342,0.165004357,1.605037434,0.752090161,3.128407648,0.304147232,DB0062410069327_,1.190243379,0.47314708,NA,10069327,Product quality issue,10077536,Product issues,Prod,testosterone,DB00624
,504426,DB01202,10052015,65,6649,102,5616,8.67076347059956e-05,0.538283453,0.387349039,0.743498825,0.00070641,DB0120210052015_,7.255314161,-0.619369994,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,levetiracetam,DB01202
,504592,DB06655,10033425,49,3639,25,2094,0.715745866,1.127845099,0.680905649,1.911561805,0.831769573,DB0665510033425_,0.184199832,0.12030882,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,liraglutide,DB06655
,504676,DB08904,10053425,181,11429,21,3538,2.29154655633215e-06,2.668122728,1.690550108,4.422416455,2.98271102772223e-05,DB0890410053425_,10.42009284,0.981375127,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,504756,DB01012,10020751,31,10601,20,8665,0.481592667,1.266915872,0.698913487,2.34709336,0.646196343,DB0101210020751_,0.436651885,0.2365855,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,cinacalcet,DB01012
,505014,DB01156,10023547,38,13584,17,6311,1,1.03847493,0.571647231,1.963747154,1,DB0115610023547_,0,0.037753223,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,bupropion,DB01156
,505329,DB00869,10003549,32,1273,20,909,0.67223154,1.14239833,0.629054658,2.122277633,0.801033888,DB0086910003549_,0.221852026,0.133129851,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,dorzolamide,DB00869
,505345,DB00904,10017412,96,22973,51,14405,0.351694035,1.180264404,0.831346067,1.692959307,0.521406565,DB0090410017412_,0.651225186,0.165738485,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,ondansetron,DB00904
,505356,DB00193,10065154,124,19196,33,8669,0.005587547,1.696909332,1.146849861,2.574915903,0.022361247,DB0019310065154_,3.800425862,0.528808556,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,tramadol,DB00193
,505487,DB11065,10047899,34,3152,23,2665,0.426393929,1.249813917,0.713014538,2.228181591,0.595065673,DB1106510047899_,0.519083504,0.222994673,NA,10047899,Weight increased,10022891,Investigations,Inv,pancrelipase amylase,DB11065
,505521,DB14500,10040829,43,7766,11,4062,0.031128869,2.044538435,1.035428486,4.401203136,0.087197988,DB1450010040829_,2.439574024,0.71517206,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,potassium,DB14500
,505618,DB06605,10012267,31,14042,25,13008,0.688442698,1.148684609,0.656009274,2.030340358,0.812186703,DB0660510012267_,0.208025035,0.138617469,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,505675,DB13867,10013710,37,4513,32,2522,0.077594764,0.6461597,0.390585717,1.074365143,0.174278251,DB1386710013710_,1.747102116,-0.436708592,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,fluticasone,DB13867
,505687,DB09079,10047700,67,590,20,857,3.6935361026827e-11,4.861174158,2.876527068,8.553931413,1.2944612861202e-09,DB0907910047700_,20.46517122,1.581280005,female,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,nintedanib,DB09079
,505883,DB05679,10047571,33,6898,18,4891,0.396289342,1.299889054,0.710016149,2.454959974,0.565971004,DB0567910047571_,0.569212431,0.262278918,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,ustekinumab,DB05679
,506027,DB13867,10033557,53,4497,13,2541,0.006322245,2.303402659,1.235756843,4.615002546,0.024697957,DB1386710033557_,3.70103476,0.834387447,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,fluticasone,DB13867
,506179,DB01181,10002034,23,550,41,879,0.792950465,0.896586079,0.50764097,1.548907615,0.887773526,DB0118110002034_,0.119038607,-0.109160973,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ifosfamide,DB01181
,506293,DB08932,10053505,98,19345,9,6588,1.62367513968326e-05,3.708238957,1.874009097,8.353747639,0.000165999,DB0893210053505_,8.703529774,1.310557089,female,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,506324,DB00678,10034474,33,15566,23,10701,1,0.986352649,0.56154594,1.760263593,1,DB0067810034474_,0,-0.013741332,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,losartan,DB00678
,506594,DB01068,10043417,56,13707,21,6819,0.331929793,1.326640006,0.789884657,2.308701599,0.500733162,DB0106810043417_,0.691681931,0.282649435,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,506618,DB00182,10000381,23,5171,34,2818,0.000232245,0.36869883,0.206919665,0.645906033,0.001632234,DB0018210000381_,6.41780594,-0.997775146,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,amphetamine,DB00182
,506787,DB06273,10003549,62,5033,9,1401,0.080665687,1.917395424,0.944510804,4.400112752,0.179473302,DB0627310003549_,1.717728817,0.650967715,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,506903,DB00904,10005728,33,23036,18,14438,0.668854375,1.149083926,0.628210857,2.16831875,0.798874778,DB0090410005728_,0.224551069,0.138965039,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,ondansetron,DB00904
,506920,DB00316,10054786,49,65425,14,36939,0.024951785,1.976088477,1.073404306,3.876451376,0.073366259,DB0031610054786_,2.612291134,0.681119374,NA,10054786,Skin burning sensation,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,507038,DB06403,10015958,48,21423,6,6655,0.035546552,2.485213502,1.061316821,7.1094913,0.096585586,DB0640310015958_,2.337325766,0.910358572,NA,10015958,Eye pain,10015919,Eye disorders,Eye,ambrisentan,DB06403
,507102,DB00112,10021058,46,5887,15,4076,0.008954728,2.123120794,1.162207643,4.099952698,0.032582366,DB0011210021058_,3.423984045,0.752887079,NA,10021058,Hypophosphataemia,10027433,Metabolism and nutrition disorders,Metab,bevacizumab,DB00112
,507104,DB09073,10013573,671,19589,15,775,0.024462979,1.769799689,1.058502438,3.19598601,0.072318601,DB0907310013573_,2.626673907,0.57086637,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,palbociclib,DB09073
,507224,DB08917,10037844,48,868,8,186,0.592604852,1.285440099,0.589814957,3.199592746,0.738771065,DB0891710037844_,0.302767196,0.251101149,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ferric carboxymaltose,DB08917
,507289,DB00455,10029354,71,9330,52,5066,0.107385485,0.741416522,0.510228489,1.083452136,0.222236632,DB0045510029354_,1.504012553,-0.299192704,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,loratadine,DB00455
,507333,DB00230,10005483,42,19632,26,8625,0.187126501,0.709694537,0.424800174,1.206510056,0.332924062,DB0023010005483_,1.099840858,-0.342920631,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,pregabalin,DB00230
,507606,DB06605,10029354,55,14018,56,12977,0.635099957,0.909210848,0.614665006,1.344384241,0.773227836,DB0660510029354_,0.257181531,-0.095178256,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,apixaban,DB06605
,507706,DB04951,10053762,26,1856,34,3023,0.423614319,1.245458912,0.715194263,2.145624716,0.592428964,DB0495110053762_,0.523524304,0.219504066,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,pirfenidone,DB04951
,507744,DB00254,10047571,38,5897,14,3374,0.192962975,1.552924213,0.821051499,3.107584128,0.340336295,DB0025410047571_,1.077821047,0.440139743,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,doxycycline,DB00254
,507780,DB00381,10022081,46,29314,12,22875,0.000292435,2.991183822,1.558910311,6.204641471,0.001976513,DB0038110022081_,6.22642113,1.095669236,female,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,508132,DB00370,10001760,46,4495,10,3653,3.47262711628394e-05,3.737745782,1.857337479,8.318918225,0.000322741,DB0037010001760_,8.038660785,1.318482698,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,mirtazapine,DB00370
,508148,DB00198,10013573,41,1234,9,994,0.000132737,3.667693715,1.745245916,8.626148891,0.00101542,DB0019810013573_,6.892452864,1.299563049,female,10013573,Dizziness,10029205,Nervous system disorders,Nerv,oseltamivir,DB00198
,508210,DB08904,10003246,62,11548,11,3548,0.097147102,1.731602948,0.902786868,3.651133496,0.20652795,DB0890410003246_,1.577319523,0.549047539,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,certolizumab pegol,DB08904
,508263,DB01609,10027175,33,1551,21,1322,0.335859145,1.339278539,0.74796007,2.448568828,0.504990889,DB0160910027175_,0.683214891,0.292131065,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,deferasirox,DB01609
,508602,DB11065,10033371,61,3125,26,2662,0.003202467,1.99828426,1.239524066,3.305342273,0.014267261,DB1106510033371_,4.249787815,0.692288943,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,pancrelipase amylase,DB11065
,508619,DB11065,10037660,71,3115,58,2630,0.928846838,1.033541486,0.717300698,1.494411334,0.970494858,DB1106510037660_,0.029949175,0.032991241,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,pancrelipase amylase,DB11065
,508757,DB01076,10012239,14,25733,37,25546,0.001150001,0.375616846,0.18756259,0.711596347,0.00618598,DB0107610012239_,5.085469904,-0.979185682,NA,10012239,Delusion,10037175,Psychiatric disorders,Psych,atorvastatin,DB01076
,508786,DB08881,10016256,69,554,79,732,0.431226245,1.153927389,0.807235752,1.646570597,0.599653112,DB0888110016256_,0.511403938,0.143171245,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,vemurafenib,DB08881
,509526,DB09153,10017577,39,7760,20,5679,0.234482138,1.427030505,0.811316497,2.585349738,0.391386759,DB0915310017577_,0.938059055,0.355595715,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,sodium chloride,DB09153
,509535,DB01202,10029350,31,6683,60,5658,0.000184514,0.437449377,0.273646173,0.686875736,0.001347586,DB0120210029350_,6.609440274,-0.826794289,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,levetiracetam,DB01202
,509569,DB01168,10010774,42,639,42,789,0.367891393,1.234562485,0.774895135,1.966936355,0.537611901,DB0116810010774_,0.620618353,0.210716644,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,procarbazine,DB01168
,509604,DB01168,10016256,115,566,145,686,0.784516055,0.961267921,0.727275946,1.268574153,0.882994177,DB0116810016256_,0.124436673,-0.039502115,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,procarbazine,DB01168
,509606,DB01168,10019211,26,655,32,799,1,0.991131402,0.561116437,1.736197589,1,DB0116810019211_,0,-0.008908158,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,procarbazine,DB01168
,509778,DB00091,10043554,31,5479,20,2650,0.368510616,0.749679867,0.413029675,1.390720396,0.538247474,DB0009110043554_,0.619436835,-0.288109008,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,cyclosporine,DB00091
,509964,DB06724,10046306,62,7867,23,3896,0.249791148,1.334977979,0.813926277,2.261321346,0.409336679,DB0672410046306_,0.893217285,0.288914797,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,calcium carbonate,DB06724
,510789,DB00451,10048706,45,47226,7,15412,0.074981521,2.097792208,0.938878136,5.515628456,0.169806853,DB0045110048706_,1.773093647,0.740885462,NA,10048706,Joint range of motion decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,levothyroxine,DB00451
,511601,DB00381,10061309,78,29282,55,22832,0.600238065,1.105828667,0.772742794,1.591912439,0.744697071,DB0038110061309_,0.29477776,0.100594979,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,amlodipine,DB00381
,511602,DB01590,10061309,43,4695,21,2846,0.440580345,1.241151461,0.71887528,2.206707553,0.608931242,DB0159010061309_,0.496049921,0.216039546,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,everolimus,DB01590
,512729,DB06273,10016173,67,5028,15,1395,0.502834696,1.239217594,0.697821303,2.343514535,0.663987841,DB0627310016173_,0.409491441,0.214480208,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,tocilizumab,DB06273
,513329,DB00697,10016825,48,6048,19,1787,0.305668921,0.746479433,0.429371388,1.348430868,0.472423566,DB0069710016825_,0.749879311,-0.292387214,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,tizanidine,DB00697
,513389,DB00758,10022067,34,8266,20,10054,0.009189161,2.067660986,1.155567751,3.79395279,0.033276448,DB0075810022067_,3.402905385,0.72641801,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,clopidogrel,DB00758
,513390,DB01076,10022067,41,25706,27,25556,0.114140282,1.509637825,0.906280832,2.552835407,0.232337746,DB0107610022067_,1.459563166,0.411869771,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,513672,DB06637,10042209,55,6107,6,2013,0.006563713,3.021362435,1.300121025,8.600743493,0.025440859,DB0663710042209_,3.671398785,1.105707867,female,10042209,Stress,10037175,Psychiatric disorders,Psych,dalfampridine,DB06637
,513823,DB01104,10022081,50,15413,10,7276,0.011866063,2.360270601,1.182157998,5.22346121,0.040813853,DB0110410022081_,3.198733731,0.858776274,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,513999,DB00203,10053405,37,13841,16,8922,0.205792359,1.490627173,0.808499895,2.87189378,0.356188204,DB0020310053405_,1.032296024,0.399196953,NA,10053405,Brain natriuretic peptide increased,10022891,Investigations,Inv,sildenafil,DB00203
,514053,DB11065,10000087,75,3111,57,2631,0.596291264,1.112729895,0.774787826,1.60557089,0.74169581,DB1106510000087_,0.298816079,0.106816361,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,pancrelipase amylase,DB11065
,514056,DB11065,10003239,58,3128,19,2669,0.000187363,2.604202782,1.52390617,4.642675375,0.001365164,DB1106510003239_,6.596480967,0.957126594,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,pancrelipase amylase,DB11065
,514143,DB11065,10012174,37,3149,25,2663,0.442630533,1.25153611,0.731380337,2.175033885,0.610681886,DB1106510012174_,0.4931791,0.224371685,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,pancrelipase amylase,DB11065
,514573,DB00563,10006825,66,46580,23,15325,0.806249276,0.944093964,0.579309235,1.591047004,0.895274781,DB0056310006825_,0.11062459,-0.05752958,NA,10006825,C-reactive protein increased,10022891,Investigations,Inv,methotrexate,DB00563
,514601,DB00635,10060946,34,33019,24,23770,1,1.019842961,0.587111245,1.797959932,1,DB0063510060946_,0,0.019648656,NA,10060946,Pneumonia bacterial,10021881,Infections and infestations,Infec,prednisone,DB00635
,514672,DB01068,10039073,71,13692,10,6830,2.52624273389213e-05,3.541461082,1.816009455,7.70628144,0.000243678,DB0106810039073_,8.319662345,1.264539377,female,10039073,Rheumatoid arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,clonazepam,DB01068
,514716,DB00814,10074903,53,8234,26,3389,0.458130845,0.83903537,0.514434888,1.400261996,0.625491858,DB0081410074903_,0.469216966,-0.175502416,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,meloxicam,DB00814
,515067,DB00404,10013954,44,19848,8,9854,0.004962458,2.730524291,1.270850043,6.718083954,0.020341243,DB0040410013954_,3.895104788,1.004493639,female,10013954,Dysphoria,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,515403,DB08932,10015967,74,19369,15,6582,0.0674551,1.676349659,0.95293433,3.147352364,0.156793493,DB0893210015967_,1.852825669,0.516618607,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,macitentan,DB08932
,515524,DB08932,10062262,48,19395,10,6587,0.175451796,1.630102733,0.813781276,3.615953197,0.317942121,DB0893210062262_,1.145885921,0.488643039,NA,10062262,Spinal operation,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,515539,DB08820,10061471,34,4367,34,3511,0.392536326,0.804010592,0.483786876,1.336173175,0.562447455,DB0882010061471_,0.575457562,-0.218142836,NA,10061471,Pseudomonas infection,10021881,Infections and infestations,Infec,ivacaftor,DB08820
,515970,DB08895,10024670,51,28063,19,6627,0.094124028,0.633879359,0.367572482,1.137693834,0.201930303,DB0889510024670_,1.599832676,-0.455896628,NA,10024670,Liver disorder,10019805,Hepatobiliary disorders,Hepat,tofacitinib,DB08895
,516272,DB08931,10047340,39,6538,12,2434,0.637947315,1.20989365,0.619357246,2.542435029,0.775186425,DB0893110047340_,0.25465173,0.190532463,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,riociguat,DB08931
,516324,DB00656,10047571,64,11949,16,6603,0.003225984,2.210310269,1.26162536,4.099961981,0.014351355,DB0065610047571_,4.243910917,0.793132899,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,trazodone,DB00656
,516334,DB00927,10064848,156,7341,120,4896,0.263610366,0.867033997,0.677062673,1.112546847,0.425457354,DB0092710064848_,0.854590563,-0.142677091,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,famotidine,DB00927
,516600,DB08912,10051398,70,1260,89,1445,0.567175005,0.902045384,0.64380148,1.259844719,0.71836337,DB0891210051398_,0.330779752,-0.103090445,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dabrafenib,DB08912
,516629,DB08911,10053762,40,1599,36,1712,0.487195988,1.189569326,0.735071037,1.931283441,0.651072578,DB0891110053762_,0.429134156,0.173591331,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,trametinib,DB08911
,516739,DB09270,10069339,19,3095,39,2329,0.000259166,0.366669966,0.199602989,0.651975932,0.001790091,DB0927010069339_,6.325489037,-1.003293112,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,ubidecarenone,DB09270
,516832,DB00331,10076308,141,24805,78,20674,0.003415626,1.506624349,1.133881955,2.014369836,0.015027154,DB0033110076308_,4.197896437,0.409871618,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,516834,DB00381,10076308,132,29228,87,22800,0.245975319,1.18355617,0.895586955,1.57074382,0.40493917,DB0038110076308_,0.90401842,0.168523609,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,516919,DB00230,10013663,215,19459,87,8564,0.530561763,1.087610657,0.842856304,1.413669979,0.687595698,DB0023010013663_,0.374554262,0.083983232,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,pregabalin,DB00230
,516922,DB00829,10013663,38,8014,34,4420,0.04764818,0.616419126,0.377233975,1.011057577,0.120672651,DB0082910013663_,2.114673763,-0.483828148,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,diazepam,DB00829
,517456,DB01195,10019211,40,1199,15,729,0.121624455,1.620981489,0.868777606,3.18230948,0.243731662,DB0119510019211_,1.411687407,0.483031823,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,flecainide,DB01195
,517835,DB06210,10051608,42,1418,26,1035,0.536354044,1.178983976,0.701038288,2.016915981,0.692660528,DB0621010051608_,0.367215259,0.164653031,NA,10051608,Platelet count increased,10022891,Investigations,Inv,eltrombopag,DB06210
,518094,DB01413,10003481,27,1193,36,1623,1,1.020326105,0.592242664,1.738927219,1,DB0141310003481_,0,0.020122287,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,cefepime,DB01413
,518096,DB09035,10003481,61,4665,70,6620,0.246293274,1.2365928,0.860773984,1.772426222,0.405284923,DB0903510003481_,0.903164946,0.212359855,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,nivolumab,DB09035
,518192,DB00203,10006002,70,13808,24,8914,0.00776709,1.882853725,1.168394738,3.133252811,0.029088545,DB0020310006002_,3.537410833,0.632788565,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sildenafil,DB00203
,518265,DB01175,10028245,39,10685,11,4881,0.171454311,1.619548863,0.812594245,3.509305415,0.312806649,DB0117510028245_,1.162170015,0.482147631,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,escitalopram,DB01175
,518314,DB00682,10076308,64,19395,42,16322,0.24128419,1.282362403,0.855030028,1.941288355,0.399405185,DB0068210076308_,0.917778876,0.248704004,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,518376,DB06186,10028606,27,2182,42,3604,0.803892427,1.061792896,0.627589611,1.768648152,0.893912871,DB0618610028606_,0.112146968,0.05995889,NA,10028606,Myocarditis,10007541,Cardiac disorders,Card,ipilimumab,DB06186
,518377,DB09035,10028606,47,4679,75,6615,0.579479483,0.885938604,0.600570362,1.295427936,0.728158438,DB0903510028606_,0.31723662,-0.121107626,NA,10028606,Myocarditis,10007541,Cardiac disorders,Card,nivolumab,DB09035
,518503,DB00165,10017577,37,2108,22,1344,0.893093179,1.072267852,0.613056003,1.917170996,0.955451035,DB0016510017577_,0.045571762,0.069775893,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,pyridoxine,DB00165
,518605,DB00115,10062352,44,18381,16,10456,0.139583631,1.564309635,0.864898658,2.971490515,0.269241633,DB0011510062352_,1.312146038,0.447444599,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,cyanocobalamin,DB00115
,518865,DB06605,10010774,182,13891,137,12896,0.07115241,1.233299025,0.981300431,1.552907006,0.163304177,DB0660510010774_,1.812140702,0.209692713,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,519032,DB00190,10048334,9,3288,42,4632,0.000488109,0.301918144,0.129031023,0.630347095,0.003032727,DB0019010048334_,5.798293052,-1.197599345,male,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,carbidopa,DB00190
,519053,DB01281,10022611,44,8888,7,1791,0.707488846,1.266592467,0.564763271,3.338421119,0.825128976,DB0128110022611_,0.19221557,0.236330197,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,abatacept,DB01281
,519561,DB00853,10065154,29,1792,36,2230,1,1.002448636,0.590350572,1.6888324,1,DB0085310065154_,0,0.002445643,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,temozolomide,DB00853
,519703,DB00207,10037153,51,9029,27,5428,0.640360117,1.135565254,0.697946299,1.885841421,0.777345664,DB0020710037153_,0.251870157,0.127130548,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,azithromycin,DB00207
,519717,DB08895,10031252,32,28082,25,6621,2.21969124231666e-05,0.301796952,0.173160558,0.531573224,0.000218233,DB0889510031252_,8.4299474,-1.198000832,male,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,519745,DB06674,10037162,42,4464,16,1474,0.647194749,0.866809281,0.475527463,1.656753403,0.78240837,DB0667410037162_,0.245378463,-0.142936302,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,golimumab,DB06674
,519746,DB08904,10037162,121,11489,57,3502,0.009583806,0.647080801,0.46739445,0.905001462,0.034421035,DB0890410037162_,3.369087426,-0.435284106,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,certolizumab pegol,DB08904
,519899,DB05676,10048439,48,47081,7,25322,0.000317034,3.687984343,1.658882708,9.665092646,0.002110484,DB0567610048439_,6.160838084,1.30508006,female,10048439,Fibromyalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,519914,DB01592,10070863,51,6225,17,3050,0.195229457,1.469823117,0.833147959,2.719600079,0.343308666,DB0159210070863_,1.069125336,0.385142065,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,iron,DB01592
,520018,DB00688,10014625,49,6441,32,5346,0.314783474,1.270903707,0.796458025,2.053762272,0.482355415,DB0068810014625_,0.729074061,0.239728227,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,mycophenolate mofetil,DB00688
,520171,DB00169,10022687,74,38617,42,18133,0.320727921,0.827339678,0.558836916,1.239194563,0.488984276,DB0016910022687_,0.715424945,-0.189539933,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,520225,DB06186,10013709,33,2176,26,3620,0.004476586,2.111248529,1.220900485,3.686512288,0.0186966,DB0618610013709_,3.979413602,0.747279492,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ipilimumab,DB06186
,520268,DB06228,10022004,40,15872,19,16057,0.005950027,2.129741859,1.204406859,3.89491713,0.023509425,DB0622810022004_,3.750353891,0.75600078,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,520314,DB00046,10070608,49,5410,41,4651,0.915871833,1.027452465,0.663354274,1.598672779,0.96236383,DB0004610070608_,0.038362698,0.027082404,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,insulin lispro,DB00046
,520325,DB00736,10070608,42,10549,28,5525,0.316310172,0.785651181,0.475060316,1.317654724,0.483975369,DB0073610070608_,0.725721264,-0.241242375,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,esomeprazole,DB00736
,520541,DB08931,10029331,51,6526,12,2434,0.157841499,1.585116657,0.831875188,3.271751523,0.294569477,DB0893110029331_,1.222240387,0.460658006,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,520975,DB00211,10002855,34,1402,17,1614,0.004498511,2.301826839,1.244439727,4.413725048,0.018774748,DB0021110002855_,3.975242511,0.833703085,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,midodrine,DB00211
,521164,DB00668,10069339,28,10063,44,4259,4.16923436060066e-08,0.26937343,0.161252311,0.443093889,8.18329416098773e-07,DB0066810069339_,14.01600087,-1.311656648,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,epinephrine,DB00668
,521199,DB00254,10070863,38,5897,40,3348,0.00882668,0.539378279,0.336018256,0.864590222,0.032212327,DB0025410070863_,3.435406064,-0.617338138,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,doxycycline,DB00254
,521388,DB06605,10062244,32,14041,21,13012,0.270863849,1.412114441,0.789085197,2.578116934,0.433557,DB0660510062244_,0.835732003,0.345088185,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,521480,DB00343,10007617,46,8690,27,5068,1,0.993597878,0.603996234,1.664375373,1,DB0034310007617_,0,-0.006422703,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,diltiazem,DB00343
,521685,DB01190,10016322,41,4893,14,2271,0.383379937,1.359232054,0.724039218,2.705359289,0.55342619,DB0119010016322_,0.591626887,0.306919874,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,clindamycin,DB01190
,521798,DB00864,10036807,25,6844,38,8354,0.447212198,0.803058907,0.46411466,1.366943793,0.615008901,DB0086410036807_,0.486118538,-0.219327209,NA,10036807,Progressive multifocal leukoencephalopathy,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,521871,DB01060,10013538,41,8546,11,5070,0.020454731,2.21112527,1.114905339,4.774902307,0.062896314,DB0106010013538_,2.766267722,0.793501558,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,amoxicillin,DB01060
,521945,DB00316,10003399,33,65441,23,36930,0.486756286,0.809697795,0.461204252,1.44439155,0.650633831,DB0031610003399_,0.429808266,-0.211094193,NA,10003399,Arthropod bite,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,522002,DB06605,10003246,66,14007,39,12994,0.030850203,1.569886286,1.040308914,2.397583797,0.08659581,DB0660510003246_,2.446503853,0.451003187,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,522056,DB05676,10016334,53,47076,14,25315,0.014775761,2.035739029,1.11323455,3.973896902,0.04873035,DB0567610016334_,3.02145325,0.710858912,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,522222,DB00540,10047899,54,2429,13,1078,0.045290055,1.843217296,0.987575988,3.697774489,0.116141376,DB0054010047899_,2.152947073,0.611512575,NA,10047899,Weight increased,10022891,Investigations,Inv,nortriptyline,DB00540
,522341,DB06605,10037400,127,13946,67,12966,0.000163257,1.762278301,1.299404978,2.408599901,0.001212381,DB0660510037400_,6.715169171,0.566607461,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,522357,DB00433,10041101,49,7607,32,5988,0.433955413,1.205336764,0.755521081,1.94740787,0.602499367,DB0043310041101_,0.506668664,0.186759,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,prochlorperazine,DB00433
,522464,DB00213,10019301,27,18868,31,13390,0.082110269,0.618121176,0.354764135,1.070773186,0.181856119,DB0021310019301_,1.704539458,-0.481070763,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,pantoprazole,DB00213
,522469,DB06605,10019301,34,14039,26,13007,0.518571032,1.211554619,0.705420769,2.103673589,0.677830797,DB0660510019301_,0.388857584,0.191904344,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,apixaban,DB06605
,522625,DB00654,10061822,43,3773,15,2583,0.022447397,1.962326264,1.066055265,3.811130993,0.067613572,DB0065410061822_,2.693946553,0.674130639,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,522717,DB09072,10036495,143,6328,48,2487,0.371881542,1.17083084,0.835815675,1.665076484,0.541546058,DB0907210036495_,0.61332716,0.157713617,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,523009,DB00531,10038687,30,7222,39,6477,0.146685097,0.689903082,0.413366525,1.141022592,0.2792914,DB0053110038687_,1.275499598,-0.371204152,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,cyclophosphamide,DB00531
,523414,DB00091,10062237,31,5479,33,2637,0.001867766,0.452163644,0.267220435,0.763439595,0.009200567,DB0009110062237_,4.688490189,-0.79371112,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,cyclosporine,DB00091
,523825,DB00158,10067482,40,16775,18,8086,0.888905932,1.071166676,0.599662706,1.986307661,0.953911952,DB0015810067482_,0.047183905,0.068748406,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,523886,DB00437,10029350,21,6900,38,11508,0.892968776,0.921688325,0.513467984,1.61242194,0.955415161,DB0043710029350_,0.045609309,-0.081548155,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,allopurinol,DB00437
,524037,DB08912,10037844,87,1243,90,1444,0.484054565,1.122935328,0.81820764,1.540595302,0.648275253,DB0891210037844_,0.4334399,0.115946086,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dabrafenib,DB08912
,524045,DB00722,10073317,49,25354,36,25996,0.130123792,1.395560948,0.888901174,2.209905075,0.255886274,DB0072210073317_,1.363022175,0.333296448,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,524055,DB01076,10018870,24,25723,47,25536,0.00612854,0.506935577,0.296398339,0.846195851,0.024073628,DB0107610018870_,3.7266383,-0.67937135,NA,10018870,Blood urine present,10022891,Investigations,Inv,atorvastatin,DB01076
,524161,DB06724,10061481,37,7892,22,3897,0.490303335,0.830494335,0.476451838,1.480115309,0.6535803,DB0672410061481_,0.425289876,-0.185734171,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,calcium carbonate,DB06724
,524402,DB00704,10013968,52,4304,55,5139,0.558883345,1.128862386,0.755836068,1.684009618,0.711740192,DB0070410013968_,0.340042333,0.121210388,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,naltrexone,DB00704
,524425,DB00684,10076309,33,2759,30,2318,0.799710188,0.924193819,0.544632639,1.573980405,0.891736807,DB0068410076309_,0.11458425,-0.078833469,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tobramycin,DB00684
,524533,DB09033,10053762,246,2378,197,1472,0.011656649,0.773034482,0.631013497,0.947853136,0.040235721,DB0903310053762_,3.213000102,-0.257431623,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,vedolizumab,DB09033
,524930,DB13961,10020100,38,9419,12,6402,0.020190104,2.152246936,1.099934748,4.527605092,0.062244531,DB1396110020100_,2.776684595,0.766512383,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,fish oil,DB13961
,525144,DB09035,10011224,59,4667,71,6619,0.371070086,1.178528531,0.818241982,1.692064508,0.540693897,DB0903510011224_,0.614901969,0.164266652,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nivolumab,DB09035
,525149,DB09035,10025482,48,4678,50,6640,0.148947974,1.362575581,0.89588604,2.070518139,0.282525528,DB0903510025482_,1.263986367,0.309376719,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,nivolumab,DB09035
,525223,DB00582,10074171,18,1112,37,1537,0.213489893,0.672514339,0.35843778,1.218971941,0.365623002,DB0058210074171_,1.006152525,-0.396731846,NA,10074171,Aspergillus infection,10021881,Infections and infestations,Infec,voriconazole,DB00582
,525539,DB00476,10023230,42,17215,15,6162,1,1.002242228,0.544065982,1.947103208,1,DB0047610023230_,0,0.002239718,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,525799,DB00788,10003246,71,9285,23,5038,0.030196097,1.674913564,1.032354089,2.813135599,0.085124884,DB0078810003246_,2.463635875,0.51576156,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,naproxen,DB00788
,525948,DB14513,10061024,40,7137,38,3526,0.005147343,0.52006215,0.324532801,0.834723832,0.020937215,DB1451310061024_,3.866227086,-0.653806955,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,magnesium,DB14513
,525954,DB08932,10022611,76,19367,24,6573,0.818543109,1.074737245,0.670833356,1.780433318,0.903211688,DB0893210022611_,0.101798326,0.072076208,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,525961,DB09570,10007739,37,3864,23,3912,0.070035684,1.628569207,0.940423324,2.876550989,0.161339873,DB0957010007739_,1.824242124,0.487701842,NA,10007739,Cataract,10015919,Eye disorders,Eye,ixazomib,DB09570
,525962,DB09570,10010305,30,3871,21,3914,0.208368661,1.444365914,0.798272784,2.659213456,0.359251599,DB0957010010305_,1.023732303,0.367670411,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,ixazomib,DB09570
,525964,DB09570,10012735,459,3442,288,3647,1.84928431810139e-11,1.688540689,1.443192023,1.978052091,6.75139919582509e-10,DB0957010012735_,21.11610116,0.523864658,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ixazomib,DB09570
,525974,DB09570,10022437,45,3856,58,3877,0.23426071,0.780114105,0.515086727,1.174874817,0.39112893,DB0957010022437_,0.938718028,-0.248315082,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,ixazomib,DB09570
,525979,DB09570,10028334,66,3835,50,3885,0.134556005,1.337155578,0.909311392,1.976986427,0.262043757,DB0957010028334_,1.339243776,0.290544655,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ixazomib,DB09570
,525980,DB09570,10033425,38,3863,44,3891,0.579412209,0.869912309,0.547088456,1.377507535,0.728091307,DB0957010033425_,0.317328816,-0.139362866,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ixazomib,DB09570
,525986,DB09570,10047899,49,3852,36,3899,0.15683792,1.37765679,0.875621914,2.186054814,0.29325874,DB0957010047899_,1.226699989,0.320384078,NA,10047899,Weight increased,10022891,Investigations,Inv,ixazomib,DB09570
,526075,DB08931,10068319,90,6487,25,2421,0.206492084,1.343477691,0.852136388,2.190279398,0.357070124,DB0893110068319_,1.02982309,0.295261543,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,526121,DB06403,10076309,151,21320,44,6617,0.799803377,1.065101508,0.755854715,1.52794211,0.891761512,DB0640310076309_,0.114556546,0.063070107,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ambrisentan,DB06403
,526147,DB00423,10070863,70,2397,22,1018,0.248258861,1.351255724,0.821316061,2.3051273,0.407634768,DB0042310070863_,0.897383682,0.301034326,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,methocarbamol,DB00423
,526154,DB09153,10047513,35,7764,19,5680,0.335089234,1.347620356,0.749147292,2.496520799,0.504269346,DB0915310047513_,0.684644738,0.298340338,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,sodium chloride,DB09153
,526192,DB06228,10039101,38,15874,21,16055,0.026534315,1.830111021,1.046610838,3.283925263,0.076935026,DB0622810039101_,2.56479403,0.604376632,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,rivaroxaban,DB06228
,526405,DB00091,10047895,86,5424,33,2637,0.279107822,1.266916298,0.836525496,1.959850077,0.442936008,DB0009110047895_,0.814329972,0.236585836,NA,10047895,Weight decreased,10022891,Investigations,Inv,cyclosporine,DB00091
,526542,DB09122,10037660,41,1217,11,326,1,0.998432291,0.497111481,2.178700555,1,DB0912210037660_,0,-0.00156894,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,peginterferon beta-1a,DB09122
,526572,DB00668,10067482,49,10042,19,4284,0.791618252,1.100191101,0.635138403,1.981410949,0.887231487,DB0066810067482_,0.119649354,0.095483893,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,526755,DB00158,10017918,45,16770,8,8096,0.005152394,2.715472912,1.266076767,6.672631506,0.020949906,DB0015810017918_,3.865621135,0.998966123,NA,10017918,Gastroenteritis viral,10021881,Infections and infestations,Infec,folic acid,DB00158
,526778,DB00051,10057362,46,25685,20,11400,1,1.020841114,0.591571556,1.822639252,1,DB0005110057362_,0,0.020626909,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,526825,DB00051,10054889,52,25679,16,11404,0.236449111,1.443341343,0.81074595,2.709458586,0.393682453,DB0005110054889_,0.932210651,0.366960803,NA,10054889,Transaminases increased,10022891,Investigations,Inv,adalimumab,DB00051
,526898,DB00704,10049177,38,4318,54,5140,0.461847122,0.837680809,0.537024626,1.295044681,0.628981197,DB0070410049177_,0.463653916,-0.177118147,NA,10049177,Drug screen positive,10022891,Investigations,Inv,naltrexone,DB00704
,526946,DB00216,10016256,52,871,7,101,0.663049603,0.861553369,0.376090127,2.308939576,0.794569675,DB0021610016256_,0.2299546,-0.149018276,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,eletriptan,DB00216
,527190,DB00905,10020751,153,2565,25,900,0.000197093,2.146995742,1.389417959,3.44494742,0.001423241,DB0090510020751_,6.554818389,0.764069536,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,bimatoprost,DB00905
,527397,DB00497,10062244,31,19236,22,16353,0.582084335,1.197896274,0.671295611,2.172364474,0.73024469,DB0049710062244_,0.314375609,0.180566913,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,oxycodone,DB00497
,527411,DB00213,10029410,43,18852,31,13390,1,0.985209326,0.606220507,1.618272014,1,DB0021310029410_,0,-0.014901146,NA,10029410,Night sweats,10040785,Skin and subcutaneous tissue disorders,Skin,pantoprazole,DB00213
,527544,DB00874,10022437,57,3278,27,1949,0.364094074,1.255118702,0.777916912,2.0715574,0.533679784,DB0087410022437_,0.627959275,0.227230151,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,guaifenesin,DB00874
,527679,DB00115,10029366,70,18355,43,10429,0.69560994,0.924952831,0.623314794,1.386599475,0.816801754,DB0011510029366_,0.202358864,-0.078012537,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,cyanocobalamin,DB00115
,527684,DB00921,10019063,36,5809,30,4873,1,1.006644459,0.601833013,1.694924051,1,DB0092110019063_,0,0.006622482,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,buprenorphine,DB00921
,527748,DB00454,10046735,75,1892,10,591,0.008757461,2.342278391,1.19566084,5.11664625,0.032024189,DB0045410046735_,3.441263771,0.851124127,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,meperidine,DB00454
,527834,DB00073,10023547,54,7352,21,6386,0.001550512,2.233370592,1.325109359,3.897685947,0.007902239,DB0007310023547_,4.840609179,0.803511921,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,rituximab,DB00073
,528020,DB00787,10020635,33,16967,32,17216,0.901522149,1.046398361,0.623353809,1.758505213,0.957028723,DB0078710020635_,0.043921874,0.045354135,NA,10020635,Hyperglycaemia,10027433,Metabolism and nutrition disorders,Metab,acyclovir,DB00787
,528023,DB01065,10035528,42,4289,34,3017,0.559725056,0.868958926,0.538278987,1.411901331,0.712424354,DB0106510035528_,0.339081543,-0.14045942,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,melatonin,DB01065
,529628,DB00814,10064848,64,8223,21,3394,0.403361037,1.257844161,0.756619419,2.172073676,0.573084234,DB0081410064848_,0.556722569,0.229399272,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,meloxicam,DB00814
,529780,DB09153,10037400,45,7754,18,5681,0.029596707,1.831549352,1.038015953,3.365650106,0.083821726,DB0915310037400_,2.479063049,0.605162249,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,530241,DB06285,10020772,69,8781,11,1095,0.472296358,0.782237507,0.409540815,1.644628873,0.638333492,DB0628510020772_,0.448894417,-0.245596868,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,teriparatide,DB06285
,530309,DB01076,10065154,177,25570,161,25422,0.444904645,1.092994406,0.877259276,1.362638722,0.612964483,DB0107610065154_,0.489448284,0.088921091,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,atorvastatin,DB01076
,530519,DB08895,10012374,109,28005,20,6626,0.368840459,1.28946163,0.794790913,2.195491205,0.538474907,DB0889510012374_,0.619014381,0.25422479,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,tofacitinib,DB08895
,530670,DB01181,10035528,17,556,34,886,0.558178043,0.796889551,0.413309545,1.482881142,0.711183222,DB0118110035528_,0.340825187,-0.227039191,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,ifosfamide,DB01181
,530914,DB01373,10037423,57,22663,16,7365,0.683943201,1.157730051,0.655209906,2.161324868,0.808956803,DB0137310037423_,0.212009759,0.146461236,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,calcium,DB01373
,530944,DB00695,10037162,69,27980,14,20514,1.04622964716237e-06,3.613342754,2.014266178,6.952433264,1.48890884004672e-05,DB0069510037162_,11.11488194,1.284633315,female,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,furosemide,DB00695
,530950,DB01373,10037162,68,22652,7,7374,0.001151981,3.162354292,1.453466419,8.167235445,0.006194603,DB0137310037162_,5.084076882,1.151316779,female,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,calcium,DB01373
,531154,DB00999,10065154,130,21300,59,12180,0.149951308,1.25998736,0.918610969,1.745834602,0.28384489,DB0099910065154_,1.259327353,0.23110169,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,hydrochlorothiazide,DB00999
,531303,DB00472,10010071,62,10697,21,4291,0.544798208,1.184298728,0.710877006,2.048447123,0.69969808,DB0047210010071_,0.357106351,0.169150809,NA,10010071,Coma,10029205,Nervous system disorders,Nerv,fluoxetine,DB00472
,531368,DB00472,10054112,59,10700,29,4283,0.40739939,0.814404711,0.512940002,1.319588775,0.576908316,DB0047210054112_,0.550071923,-0.205297849,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,fluoxetine,DB00472
,531407,DB01065,10028372,56,4275,36,3015,0.749474934,1.0970853,0.707096369,1.721534764,0.858009244,DB0106510028372_,0.153140405,0.092656936,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,melatonin,DB01065
,531417,DB00404,10001488,38,19854,32,9830,0.030272432,0.587943739,0.357442767,0.972779681,0.085287409,DB0040410001488_,2.461728441,-0.531124018,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,531556,DB06228,10042128,53,15859,20,16056,8.82318708656998e-05,2.682960289,1.576377171,4.740245808,0.000717344,DB0622810042128_,7.239954377,0.98692077,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,rivaroxaban,DB06228
,531606,DB00328,10013573,32,728,19,796,0.045248322,1.840805364,1.002032335,3.469988161,0.116057001,DB0032810013573_,2.153673824,0.610203174,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,indomethacin,DB00328
,531809,DB09122,10019211,50,1208,11,326,0.633194667,1.226517592,0.62132469,2.643283843,0.771855578,DB0912210019211_,0.258957822,0.204178928,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,peginterferon beta-1a,DB09122
,531824,DB06228,10028836,44,15868,20,16056,0.00249204,2.226020872,1.283995346,3.988691623,0.011630554,DB0622810028836_,4.454119677,0.800215629,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,rivaroxaban,DB06228
,531909,DB00476,10017955,42,17215,45,6132,5.12466450158179e-07,0.33248788,0.21281103,0.518482534,7.92596683872182e-06,DB0047610017955_,11.74536625,-1.10115187,male,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,duloxetine,DB00476
,532259,DB01181,10000880,36,537,26,894,0.001909475,2.303785314,1.336079388,4.021760897,0.009368615,DB0118110000880_,4.670390053,0.834553559,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ifosfamide,DB01181
,532274,DB00814,10016807,37,8250,15,3400,1,1.016571043,0.543759108,1.996488051,1,DB0081410016807_,0,0.016435242,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,meloxicam,DB00814
,532494,DB08932,10011953,37,19406,19,6578,0.16484898,0.660106096,0.369712494,1.216078431,0.303946088,DB0893210011953_,1.190904934,-0.415354705,NA,10011953,Decreased activity,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,532535,DB08904,10047461,47,11563,12,3547,0.646455616,1.201436945,0.62669078,2.490914784,0.781892411,DB0890410047461_,0.24603813,0.183518295,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,532560,DB04951,10013709,15,1867,53,3004,0.005506562,0.455442226,0.237736427,0.823010087,0.022101083,DB0495110013709_,3.812128657,-0.786486406,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pirfenidone,DB04951
,532624,DB08931,10024264,59,6518,17,2429,0.436639179,1.293296041,0.741930806,2.371573376,0.605202532,DB0893110024264_,0.502192113,0.25719403,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,532748,DB08932,10030041,61,19382,18,6579,0.697897172,1.150311438,0.670252416,2.069772092,0.818262916,DB0893210030041_,0.200571581,0.140032721,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,macitentan,DB08932
,532856,DB09034,10041349,68,1108,44,634,0.544837499,0.884375408,0.588439443,1.340552837,0.699731447,DB0903410041349_,0.357058665,-0.122873637,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,suvorexant,DB09034
,532881,DB00115,10061599,40,18385,12,10460,0.059452532,1.896434036,0.974861209,3.973322757,0.142479013,DB0011510061599_,1.948560569,0.6399753,NA,10061599,Lower limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,532952,DB09183,10023126,28,447,42,685,1,1.021616534,0.600392202,1.715283605,1,DB0918310023126_,0,0.02138621,NA,10023126,Jaundice,10019805,Hepatobiliary disorders,Hepat,dasabuvir,DB09183
,533007,DB00531,10011831,51,7201,55,6461,0.379790721,0.831995918,0.556176364,1.242603156,0.549910436,DB0053110011831_,0.597999858,-0.183927744,NA,10011831,Cytomegalovirus infection,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,533030,DB00555,10022095,40,7007,11,3475,0.099804078,1.803301173,0.906725291,3.901956009,0.210491068,DB0055510022095_,1.558312057,0.58961897,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,lamotrigine,DB00555
,533185,DB00252,10003591,42,2190,26,1882,0.220167874,1.388087218,0.827859411,2.367920933,0.373663442,DB0025210003591_,0.984399774,0.327926698,NA,10003591,Ataxia,10029205,Nervous system disorders,Nerv,phenytoin,DB00252
,533267,DB00343,10062355,102,8634,34,5061,0.004093703,1.758445609,1.180184358,2.678930956,0.017404446,DB0034310062355_,4.051029596,0.564430242,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,533286,DB00563,10018651,27,46619,38,15310,7.71443168988449e-09,0.233362237,0.136965253,0.392504488,1.77715895678014e-07,DB0056310018651_,15.54307965,-1.455163368,male,10018651,Graft versus host disease,10021428,Immune system disorders,Immun,methotrexate,DB00563
,533290,DB01073,10018651,41,1024,50,1600,0.274893705,1.281112398,0.820027762,1.991612828,0.438128036,DB0107310018651_,0.825244092,0.247728761,NA,10018651,Graft versus host disease,10021428,Immune system disorders,Immun,fludarabine,DB01073
,533513,DB00051,10063829,56,25675,32,11388,0.24942597,0.776180969,0.493773601,1.239332199,0.408852959,DB0005110063829_,0.894399701,-0.253369579,NA,10063829,Device malfunction,10077536,Product issues,Prod,adalimumab,DB00051
,533524,DB00688,10016288,44,6446,29,5349,0.348276122,1.259007258,0.769081709,2.089729031,0.517858174,DB0068810016288_,0.65805387,0.23032352,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,mycophenolate mofetil,DB00688
,533525,DB00864,10016288,73,6796,44,8348,0.000171021,2.037902644,1.381037678,3.037869183,0.001264144,DB0086410016288_,6.673359985,0.711921163,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,tacrolimus,DB00864
,533529,DB00563,10066274,38,46608,31,15317,0.000242108,0.402848467,0.244020489,0.669823523,0.001688459,DB0056310066274_,6.383938996,-0.909194801,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,methotrexate,DB00563
,533596,DB00635,10065110,20,33033,31,23763,0.006867028,0.46411208,0.250678123,0.840849311,0.026402373,DB0063510065110_,3.634301368,-0.767629204,NA,10065110,Epstein-Barr viraemia,10021881,Infections and infestations,Infec,prednisone,DB00635
,534037,DB00316,10059203,40,65434,13,36940,0.086724954,1.737031245,0.909980198,3.540140852,0.189584615,DB0031610059203_,1.662919835,0.552177475,NA,10059203,Infusion site bruising,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,534216,DB00586,10039906,36,7073,22,2783,0.108529597,0.643888119,0.367917485,1.151161551,0.223828987,DB0058610039906_,1.496872967,-0.440230296,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,diclofenac,DB00586
,534239,DB00987,10039906,60,2044,41,2887,0.00033935,2.06668945,1.360411135,3.166765735,0.002235263,DB0098710039906_,6.103396285,0.725948028,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,cytarabine,DB00987
,534336,DB08904,10028810,235,11375,70,3489,0.891447804,1.029730899,0.783085625,1.368546134,0.954926275,DB0890410028810_,0.046121141,0.029297505,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,534338,DB08904,10068319,84,11526,12,3547,0.010629984,2.153975586,1.168812691,4.339600435,0.037369151,DB0890410068319_,3.286909761,0.767315245,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,certolizumab pegol,DB08904
,534387,DB01234,10052015,33,31592,44,32844,0.305506545,0.779727406,0.480874555,1.253141701,0.472283687,DB0123410052015_,0.750175442,-0.2488109,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,dexamethasone,DB01234
,535714,DB01101,10016322,37,7552,15,3893,0.467182585,1.271569231,0.680206365,2.49694446,0.633719224,DB0110110016322_,0.456149288,0.240251752,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,536294,DB00646,10000059,37,3416,14,1986,0.190509506,1.536395176,0.808871692,3.084540384,0.337185534,DB0064610000059_,1.087121954,0.429438878,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,nystatin,DB00646
,537201,DB00112,10025256,32,5901,18,4073,0.564841649,1.227027112,0.667234909,2.325147488,0.716495559,DB0011210025256_,0.33338323,0.204594262,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,bevacizumab,DB00112
,537206,DB01075,10025256,36,19912,14,11083,0.301958768,1.431238862,0.752937054,2.873908817,0.46829415,DB0107510025256_,0.758658654,0.358540406,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,diphenhydramine,DB01075
,537770,DB00158,10061520,53,16762,12,8092,0.016354854,2.132127905,1.124139828,4.386154772,0.05271134,DB0015810061520_,2.942924673,0.757120497,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,537996,DB08895,10018627,42,28072,12,6634,0.602454641,0.827152642,0.427214114,1.726907438,0.746381968,DB0889510018627_,0.292517788,-0.189766028,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,tofacitinib,DB08895
,538048,DB00338,10062262,36,33638,17,22255,0.265095472,1.401032922,0.766596323,2.660762959,0.427054484,DB0033810062262_,0.850843676,0.337209766,NA,10062262,Spinal operation,10042613,Surgical and medical procedures,Surg,omeprazole,DB00338
,539108,DB09153,10036790,61,7738,52,5647,0.444521452,0.856095109,0.58063721,1.266261047,0.612590576,DB0915310036790_,0.490058468,-0.155373801,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sodium chloride,DB09153
,539753,DB00904,10048908,37,23032,17,14439,0.328674897,1.364440918,0.748991888,2.585084417,0.497307142,DB0090410048908_,0.698547453,0.310744761,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,ondansetron,DB00904
,539754,DB01240,10048908,44,5707,8,1568,0.395793407,1.511032117,0.701739998,3.723954108,0.565447524,DB0124010048908_,0.570137783,0.412792939,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,epoprostenol,DB01240
,539854,DB00537,10047924,36,7521,17,4281,0.569649452,1.205323083,0.658816094,2.291372667,0.72049061,DB0053710047924_,0.327822896,0.18674765,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ciprofloxacin,DB00537
,540938,DB08934,10027599,49,4440,18,6186,2.96743745522342e-07,3.792252821,2.166664834,6.927097022,4.85025086955281e-06,DB0893410027599_,12.23648013,1.332960254,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,sofosbuvir,DB08934
,541515,DB00635,10005555,41,33012,27,23767,0.80598702,1.093278036,0.656334939,1.848599459,0.895068183,DB0063510005555_,0.110855382,0.089180556,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,prednisone,DB00635
,541542,DB00381,10007632,40,29320,37,22850,0.491040423,0.842526033,0.525019311,1.355234974,0.654231062,DB0038110007632_,0.424294684,-0.171350717,NA,10007632,Cardiomegaly,10007541,Cardiac disorders,Card,amlodipine,DB00381
,541676,DB00158,10065154,185,16630,71,8033,0.107512427,1.25858282,0.95105027,1.68126618,0.222436035,DB0015810065154_,1.503115703,0.229986342,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,folic acid,DB00158
,541678,DB00586,10065154,43,7066,22,2783,0.334019647,0.76982168,0.449471763,1.354026862,0.50306431,DB0058610065154_,0.687037264,-0.261596375,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,diclofenac,DB00586
,541869,DB00421,10001551,36,8867,18,5234,0.67239194,1.180579217,0.652307101,2.210699198,0.801083994,DB0042110001551_,0.221789476,0.16600518,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,spironolactone,DB00421
,541931,DB06605,10003553,45,14028,11,13022,1.23641643271942e-05,3.79718553,1.932796223,8.144417242,0.000130703,DB0660510003553_,8.942585908,1.334260142,female,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,542108,DB06605,10013781,59,14014,26,13007,0.001468132,2.106033079,1.30595015,3.483701511,0.007555566,DB0660510013781_,4.885470757,0.744806121,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,542680,DB06605,10021015,35,14038,26,13007,0.442284221,1.247275641,0.729194119,2.158958856,0.610403547,DB0660510021015_,0.493634988,0.220961686,NA,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,apixaban,DB06605
,542880,DB06605,10027599,75,13998,19,13014,3.30603751032906e-08,3.669529921,2.193724453,6.434524066,6.61836983693826e-07,DB0660510027599_,14.22824656,1.300063567,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,542928,DB00563,10029155,22,46624,35,15313,4.92235652286078e-09,0.206473473,0.115344178,0.362039491,1.18429419865808e-07,DB0056310029155_,15.94894867,-1.577583335,male,10029155,Nephropathy toxic,10038359,Renal and urinary disorders,Renal,methotrexate,DB00563
,542930,DB00635,10029155,36,33017,43,23751,0.02952312,0.602271403,0.375665828,0.96041797,0.083662897,DB0063510029155_,2.48095968,-0.5070471,NA,10029155,Nephropathy toxic,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,543154,DB06605,10034474,67,14006,41,12992,0.042256958,1.515809451,1.011889098,2.295423417,0.110207286,DB0660510034474_,2.205392269,0.415949587,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,apixaban,DB06605
,543364,DB00727,10040753,46,3797,9,4164,7.1500025970267e-08,5.603807822,2.705590108,13.03944237,1.3357343160117e-06,DB0072710040753_,13.52602937,1.723446335,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,nitroglycerin,DB00727
,543369,DB06605,10040753,113,13960,35,12998,1.34238952715453e-09,3.005724479,2.039615739,4.530709946,3.63385259745178e-08,DB0660510040753_,17.13038734,1.10051863,female,10040753,Sinusitis,10021881,Infections and infestations,Infec,apixaban,DB06605
,543435,DB00635,10043645,48,33005,46,23748,0.174342939,0.750824097,0.490336673,1.150844774,0.316565636,DB0063510043645_,1.150224678,-0.28658388,NA,10043645,Thrombotic microangiopathy,10005329,Blood and lymphatic system disorders,Blood,prednisone,DB00635
,543488,DB00758,10046306,43,8257,30,10044,0.024496472,1.743461317,1.067650198,2.881164007,0.072391901,DB0075810046306_,2.625660846,0.5558724,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,clopidogrel,DB00758
,543493,DB06605,10046306,52,14021,21,13012,0.000930034,2.297812855,1.359491508,4.018684522,0.005188019,DB0660510046306_,5.261403374,0.831957738,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,apixaban,DB06605
,543917,DB00264,10058920,48,29559,26,24866,0.079478574,1.553029007,0.944119519,2.608650472,0.177545941,DB0026410058920_,1.72852588,0.440207222,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,544402,DB00182,10048959,37,5157,16,2836,0.473475822,1.271713694,0.688773344,2.453052381,0.63940156,DB0018210048959_,0.447222602,0.240365356,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,544834,DB00341,10047461,66,11339,24,5044,0.425217259,1.223266597,0.755343399,2.043995085,0.593991213,DB0034110047461_,0.520890753,0.201524819,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,cetirizine,DB00341
,544986,DB00364,10054112,36,2714,19,1381,0.886667907,0.964155307,0.536216822,1.786440243,0.952901543,DB0036410054112_,0.048243693,-0.03650289,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,sucralfate,DB00364
,545080,DB06262,10013710,33,3767,25,4289,0.146059056,1.502825398,0.865090618,2.641398124,0.278512987,DB0626210013710_,1.278290588,0.407346935,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,545313,DB06724,10005395,50,7879,15,3904,0.111685452,1.651584114,0.911145839,3.170958608,0.228597734,DB0672410005395_,1.475791441,0.501734897,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,calcium carbonate,DB06724
,545341,DB00788,10054112,42,9314,30,5031,0.265455963,0.756254317,0.46156626,1.252978465,0.42747802,DB0078810054112_,0.849852407,-0.279377561,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,naproxen,DB00788
,545644,DB00404,10036495,38,19854,14,9848,0.3792942,1.346360407,0.712659218,2.691453432,0.549312546,DB0040410036495_,0.599087699,0.297404957,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,545807,DB00787,10054112,59,16941,52,17196,0.505976136,1.1516882,0.779252502,1.706538817,0.666779441,DB0078710054112_,0.40529596,0.141228865,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,acyclovir,DB00787
,546112,DB00455,10016334,43,9358,11,5107,0.022092486,2.133233975,1.080605365,4.591481432,0.066835587,DB0045510016334_,2.705519602,0.757639127,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,loratadine,DB00455
,546450,DB01306,10047571,52,4156,41,3825,0.467414428,1.167257862,0.75832253,1.807336085,0.633935566,DB0130610047571_,0.455807961,0.15465729,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,insulin aspart,DB01306
,546460,DB09037,10013709,75,2451,76,2759,0.562933804,1.11082911,0.792611957,1.556405811,0.715058959,DB0903710013709_,0.335390279,0.105106683,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pembrolizumab,DB09037
,546686,DB09027,10013786,36,5143,39,7113,0.293522688,1.276619764,0.787363571,2.064751776,0.459199706,DB0902710013786_,0.778270074,0.244215775,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,ledipasvir,DB09027
,547538,DB01263,10069339,22,602,32,833,0.889285692,0.951332369,0.521008066,1.708026265,0.953995558,DB0126310069339_,0.047096264,-0.049891784,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,posaconazole,DB01263
,547836,DB08932,10038683,85,19358,16,6581,0.028920797,1.805918619,1.049691705,3.304437901,0.082297622,DB0893210038683_,2.497413061,0.591069393,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,547915,DB06262,10002855,57,3743,42,4272,0.033357422,1.548849357,1.018918889,2.371269162,0.09205828,DB0626210002855_,2.385333429,0.437512305,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,droxidopa,DB06262
,547924,DB01060,10016807,39,8548,27,5054,0.525855541,0.854042731,0.508950839,1.452641712,0.683806015,DB0106010016807_,0.380081005,-0.15777405,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,amoxicillin,DB01060
,547965,DB01183,10028813,37,522,22,526,0.060992723,1.693899642,0.958327521,3.058960967,0.145295789,DB0118310028813_,1.928983693,0.527033351,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,naloxone,DB01183
,548051,DB06605,10000060,103,13970,58,12975,0.002540287,1.649340986,1.183045942,2.318461797,0.011806463,DB0660510000060_,4.439108179,0.500375805,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,548098,DB01224,10028810,43,8065,20,5897,0.097695247,1.571994393,0.903852119,2.823912194,0.2074416,DB0122410028810_,1.572905426,0.452345127,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,quetiapine,DB01224
,548199,DB08932,10028372,145,19298,51,6546,0.805113323,0.964408855,0.695500012,1.356105412,0.894532546,DB0893210028372_,0.111453993,-0.036239951,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,548232,DB00688,10037087,63,6427,32,5346,0.022837049,1.637543022,1.052027738,2.59453674,0.068508541,DB0068810037087_,2.680796858,0.493196961,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,mycophenolate mofetil,DB00688
,548512,DB08904,10061623,115,11495,28,3531,0.321160517,1.261594535,0.827170441,1.98471619,0.489451628,DB0890410061623_,0.714469641,0.232376424,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,548515,DB06403,10019194,47,21424,14,6647,1,1.041606079,0.563348234,2.049919543,1,DB0640310019194_,0,0.040763828,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,548516,DB00203,10051076,43,13835,26,8912,0.901826143,1.06535247,0.639370611,1.807483213,0.957112391,DB0020310051076_,0.043834453,0.063305703,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,548743,DB11750,10000059,72,2428,45,1468,0.847258418,0.967365364,0.653457814,1.445375823,0.923422794,DB1175010000059_,0.079668085,-0.033179022,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,clobetasol,DB11750
,548811,DB01026,10003239,38,1072,15,1053,0.002135536,2.487582533,1.327234916,4.898382925,0.010268464,DB0102610003239_,4.578677807,0.911311369,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ketoconazole,DB01026
,548813,DB05676,10040882,48,47081,30,25299,0.552836796,0.85976965,0.533639553,1.405721985,0.706536098,DB0567610040882_,0.347380985,-0.151090775,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,549023,DB06605,10027175,110,13963,68,12965,0.008371574,1.501998414,1.099021131,2.065375105,0.030870767,DB0660510027175_,3.477945599,0.406796497,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,549254,DB08932,10052428,44,19399,17,6580,0.658879696,0.877930824,0.491160413,1.640206377,0.791655557,DB0893210052428_,0.233628884,-0.130187476,NA,10052428,Wound,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,549691,DB00316,10069351,62,65412,29,36924,0.445544832,1.206789544,0.764583282,1.946115479,0.613454121,DB0031610069351_,0.488649799,0.187963564,NA,10069351,Acute lung injury,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,acetaminophen,DB00316
,549888,DB00804,10010144,62,2938,18,881,1,1.032870169,0.599291057,1.865564946,1,DB0080410010144_,0,0.032341499,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,dicyclomine,DB00804
,549963,DB00211,10041349,22,1414,30,1601,0.575971635,0.830366564,0.454126547,1.496230036,0.725363027,DB0021110041349_,0.321083022,-0.185888033,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,midodrine,DB00211
,550077,DB00331,10015137,33,24913,31,20721,0.706593565,0.885398068,0.525469981,1.495343215,0.824363048,DB0033110015137_,0.193144254,-0.121717941,NA,10015137,Eructation,10017947,Gastrointestinal disorders,Gastr,metformin,DB00331
,550102,DB00457,10070863,33,646,20,491,0.47968283,1.253866729,0.68881924,2.3361744,0.644595118,DB0045710070863_,0.439132884,0.22623216,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,prazosin,DB00457
,550547,DB06605,10017788,15,14058,194,12839,1.92217936799797e-44,0.070594676,0.038772247,0.11947881,8.78686690223073e-42,DB0660510017788_,94.5353157,-2.650800554,male,10017788,Gastric haemorrhage,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,550850,DB00572,10028810,50,2852,10,2116,3.13861749034412e-05,3.708838646,1.853472741,8.222412567,0.000295112,DB0057210028810_,8.128155599,1.310718794,female,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,atropine,DB00572
,550981,DB08907,10076309,82,4171,52,3858,0.036289949,1.458516034,1.015013094,2.112307895,0.098105657,DB0890710076309_,2.321710247,0.377419504,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,canagliflozin,DB08907
,551004,DB00563,10035742,79,46567,36,15312,0.105482986,0.72157395,0.480490348,1.102494452,0.219335519,DB0056310035742_,1.517152672,-0.326320411,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,551398,DB00421,10023232,71,8832,22,5230,0.006876793,1.910996132,1.168680878,3.242601686,0.026430254,DB0042110023232_,3.633245942,0.647624641,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,spironolactone,DB00421
,552060,DB01593,10003239,45,1088,8,690,0.000276983,3.565328321,1.65040354,8.811149034,0.001891041,DB0159310003239_,6.270627734,1.271256145,female,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,zinc,DB01593
,552062,DB01593,10053762,40,1093,20,678,0.500192933,1.240458537,0.701387194,2.259875004,0.661779581,DB0159310053762_,0.412822738,0.215481099,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,zinc,DB01593
,552142,DB08931,10005483,43,6534,14,2432,0.765703821,1.143187348,0.61216357,2.266722046,0.870844598,DB0893110005483_,0.138291736,0.13382028,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,riociguat,DB08931
,552350,DB01238,10040108,27,5223,45,3457,0.000143467,0.397169003,0.236477107,0.655513276,0.00108581,DB0123810040108_,6.825429168,-0.923393389,NA,10040108,Serotonin syndrome,10029205,Nervous system disorders,Nerv,aripiprazole,DB01238
,552406,DB00210,10037844,66,819,21,328,0.458723805,1.258420744,0.745675875,2.20287415,0.626113965,DB0021010037844_,0.468222871,0.229857557,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,adapalene,DB00210
,552583,DB00019,10022086,85,18927,23,9506,0.007586322,1.856088253,1.158721894,3.085821668,0.028547346,DB0001910022086_,3.556191301,0.618471183,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,552734,DB00818,10013700,42,1378,19,1658,0.000372598,2.658882069,1.504546276,4.864558008,0.002416716,DB0081810013700_,6.025345774,0.97790576,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,propofol,DB00818
,552772,DB05679,10028334,36,6895,17,4892,0.208145405,1.502418892,0.821213621,2.855893593,0.358960861,DB0567910028334_,1.024541918,0.407076404,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ustekinumab,DB05679
,553172,DB08931,10049438,52,6525,17,2429,0.78570446,1.138660431,0.646388162,2.104707737,0.883734037,DB0893110049438_,0.123599125,0.129852511,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,553239,DB06168,10037844,48,561,36,364,0.560989799,0.865251124,0.538172045,1.401388461,0.713534974,DB0616810037844_,0.337523826,-0.144735498,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,canakinumab,DB06168
,553305,DB00490,10048010,47,4023,12,1564,0.242660758,1.522616508,0.792626378,3.161902782,0.400876,DB0049010048010_,0.914103127,0.420430242,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,buspirone,DB00490
,553483,DB01590,10027452,44,4694,10,2857,0.002889601,2.677747622,1.325092325,5.977241726,0.013108933,DB0159010027452_,4.334461344,0.984976002,NA,10027452,Metastases to bone,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,everolimus,DB01590
,553873,DB00571,10040984,77,5046,35,2574,0.615743903,1.122212334,0.741040255,1.729801596,0.757025585,DB0057110040984_,0.278358228,0.115302035,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,propranolol,DB00571
,553924,DB00497,10061520,37,19230,20,16355,0.110962321,1.573390227,0.889457102,2.862254245,0.227534003,DB0049710061520_,1.480455588,0.453232672,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,554056,DB01109,10001052,20,4392,34,4236,0.054987834,0.567382184,0.308927989,1.016200044,0.134320452,DB0110910001052_,2.007526898,-0.566722156,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,heparin,DB01109
,554155,DB00927,10006451,71,7426,19,4997,0.000202683,2.514365278,1.496255994,4.424563965,0.001457402,DB0092710006451_,6.531099654,0.922020397,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,famotidine,DB00927
,554189,DB00341,10005724,47,11358,12,5056,0.090304627,1.74344719,0.909651515,3.61384491,0.195725179,DB0034110005724_,1.63104375,0.555864297,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,cetirizine,DB00341
,554202,DB00993,10047899,45,3204,13,1606,0.091957331,1.7349138,0.916502085,3.516053794,0.198358577,DB0099310047899_,1.61767889,0.550957729,NA,10047899,Weight increased,10022891,Investigations,Inv,azathioprine,DB00993
,554247,DB09122,10016256,68,1190,10,327,0.065595996,1.867869608,0.942589584,4.116383464,0.153486514,DB0912210016256_,1.874142576,0.624798534,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,peginterferon beta-1a,DB09122
,554367,DB01592,10037153,44,6232,19,3048,0.688930803,1.13260452,0.646367435,2.057944161,0.812479638,DB0159210037153_,0.207664427,0.124519866,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,iron,DB01592
,554474,DB00443,10037087,53,2093,20,1170,0.140532427,1.481202242,0.865774626,2.629385192,0.270575362,DB0044310037087_,1.307204617,0.392854084,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,betamethasone,DB00443
,554585,DB00051,10073317,104,25627,24,11396,0.002797407,1.926948341,1.226158535,3.143625331,0.012761167,DB0005110073317_,4.361348552,0.655937581,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,554808,DB00198,10013709,59,1216,37,966,0.294253994,1.266627847,0.817967868,1.983393884,0.460056283,DB0019810013709_,0.776406444,0.236358131,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,oseltamivir,DB00198
,554987,DB00169,10025327,44,38647,20,18155,1,1.033452249,0.596266625,1.851539261,1,DB0016910025327_,0,0.032904896,NA,10025327,Lymphopenia,10005329,Blood and lymphatic system disorders,Blood,cholecalciferol,DB00169
,555211,DB00820,10051055,32,11883,31,5785,0.006966375,0.502539039,0.296642134,0.852442795,0.026686755,DB0082010051055_,3.623587913,-0.688081953,NA,10051055,Deep vein thrombosis,10047065,Vascular disorders,Vasc,tadalafil,DB00820
,555690,DB01060,10019303,34,8553,16,5065,0.557914442,1.258405374,0.675092027,2.4440402,0.710933517,DB0106010019303_,0.34117636,0.229845343,NA,10019303,Heart rate increased,10022891,Investigations,Inv,amoxicillin,DB01060
,555763,DB00193,10014011,48,19272,14,8688,0.170114992,1.545610453,0.837630345,3.037294905,0.311006469,DB0019310014011_,1.167941566,0.435418947,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,tramadol,DB00193
,556201,DB06605,10049848,63,14010,64,12969,0.656463787,0.911236889,0.632619361,1.312145936,0.789956965,DB0660510049848_,0.23577681,-0.092952383,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,apixaban,DB06605
,556231,DB01234,10061907,21,31604,36,32852,0.084028149,0.60637609,0.336255577,1.067382597,0.185097833,DB0123410061907_,1.686870767,-0.500254876,NA,10061907,Parainfluenzae virus infection,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,556328,DB00852,10013573,42,1124,20,451,0.567646429,0.842725679,0.477700535,1.532885399,0.718752656,DB0085210013573_,0.330237992,-0.171113785,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pseudoephedrine,DB00852
,556415,DB09076,10011224,38,770,22,588,0.352019648,1.318754877,0.751028081,2.368037592,0.521756877,DB0907610011224_,0.650553553,0.276688016,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,umeclidinium,DB09076
,556622,DB00788,10016807,42,9314,16,5045,0.270685173,1.421818649,0.781820465,2.7119148,0.433363368,DB0078810016807_,0.836178717,0.351936791,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,naproxen,DB00788
,556861,DB00381,10021688,38,29322,21,22866,0.237692293,1.411099138,0.807128692,2.531773552,0.395151498,DB0038110021688_,0.928486047,0.344368931,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,amlodipine,DB00381
,556966,DB04951,10019211,77,1805,64,2993,6.56302700762219e-05,1.994738738,1.405444352,2.839111974,0.000555585,DB0495110019211_,7.495488815,0.690513083,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pirfenidone,DB04951
,557407,DB01222,10040070,36,9238,36,5369,0.026738247,0.58123675,0.355385379,0.950509213,0.077428094,DB0122210040070_,2.55840559,-0.542597118,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,budesonide,DB01222
,557456,DB00921,10065154,44,5801,39,4864,0.825498776,0.946008396,0.59954333,1.49758945,0.907778709,DB0092110065154_,0.096754642,-0.055503835,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,buprenorphine,DB00921
,557457,DB00598,10069339,36,1552,51,977,0.000301363,0.444498702,0.279597443,0.700224644,0.002025883,DB0059810069339_,6.201749655,-0.810808144,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,labetalol,DB00598
,557598,DB06262,10037844,44,3756,27,4287,0.011800054,1.859855573,1.123892395,3.129994851,0.040624023,DB0626210037844_,3.203395694,0.620498836,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,droxidopa,DB06262
,557805,DB00169,10076308,175,38516,82,18093,1,1.002521449,0.766452355,1.320521946,1,DB0016910076308_,0,0.002518276,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,557807,DB00635,10076308,202,32851,137,23657,0.619375958,1.061807425,0.84992135,1.329740645,0.760157681,DB0063510076308_,0.274229393,0.059972574,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,558180,DB06605,10012174,141,13932,111,12922,0.205597011,1.178174009,0.911122404,1.526603943,0.355967291,DB0660510012174_,1.032916431,0.16396579,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,apixaban,DB06605
,558219,DB00704,10053425,143,4213,126,5068,0.012910927,1.365188646,1.06299776,1.755022588,0.043640636,DB0070410053425_,3.131766556,0.311292621,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,558465,DB01590,10054112,31,4707,33,2834,0.027033233,0.56566057,0.334210717,0.955012357,0.078088746,DB0159010054112_,2.549909336,-0.569761081,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,everolimus,DB01590
,558468,DB01254,10065154,33,3434,42,3106,0.162908038,0.710707923,0.435221292,1.151795221,0.301244348,DB0125410065154_,1.199833557,-0.341493732,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,dasatinib,DB01254
,558470,DB06589,10065154,27,2003,49,2604,0.199037134,0.71640458,0.428919264,1.17361579,0.347886495,DB0658910065154_,1.055879015,-0.333510215,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,pazopanib,DB06589
,558738,DB06262,10020937,43,3757,25,4289,0.007085332,1.963374842,1.169887854,3.361219671,0.027045883,DB0626210020937_,3.610220491,0.674664851,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,558739,DB06262,10033425,36,3764,34,4280,0.471570996,1.203945162,0.730636164,1.987651099,0.637763043,DB0626210033425_,0.44978847,0.1856038,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,droxidopa,DB06262
,558742,DB08932,10013781,118,19325,29,6568,0.128180052,1.38288137,0.913792977,2.156138126,0.253086398,DB0893210013781_,1.374024356,0.324169272,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,558763,DB00656,10076308,75,11938,34,6585,0.367723117,1.216714269,0.800170901,1.8845176,0.537455635,DB0065610076308_,0.620909063,0.196154004,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,558764,DB00706,10076308,9,1066,65,15860,0.051002998,2.059918772,0.899272692,4.171160249,0.126903994,DB0070610076308_,2.064324431,0.722666551,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tamsulosin,DB00706
,558766,DB00761,10076308,88,15219,33,8592,0.046185747,1.505462074,0.997589687,2.321636548,0.117857615,DB0076110076308_,2.138278036,0.409099877,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,558773,DB11089,10076308,57,10118,26,8381,0.01088727,1.815870051,1.122126129,3.011478175,0.0380953,DB1108910076308_,3.267664356,0.59656472,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,558794,DB00869,10013968,38,1267,16,913,0.092609533,1.711031032,0.924863586,3.308182312,0.199405413,DB0086910013968_,1.612415276,0.537096132,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dorzolamide,DB00869
,558872,DB00153,10021143,34,7389,19,3420,0.554072441,0.828290213,0.458487057,1.539542272,0.707632968,DB0015310021143_,0.345829727,-0.188391687,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ergocalciferol,DB00153
,558914,DB00476,10034960,41,17216,12,6165,0.640476551,1.223480159,0.630321722,2.559240871,0.777426154,DB0047610034960_,0.251766618,0.201699387,NA,10034960,Photophobia,10015919,Eye disorders,Eye,duloxetine,DB00476
,558996,DB01611,10065154,78,11835,20,2341,0.338188326,0.771447999,0.466126092,1.334268479,0.507257274,DB0161110065154_,0.678736959,-0.259486012,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,hydroxychloroquine,DB01611
,558997,DB08868,10065154,48,9154,7,2504,0.137812453,1.875585637,0.842437497,4.919905646,0.266656875,DB0886810065154_,1.32179256,0.62892095,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,fingolimod,DB08868
,559044,DB08895,10013082,78,28036,19,6627,0.897202661,0.970378387,0.581426714,1.69846405,0.956338178,DB0889510013082_,0.044643686,-0.030069194,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,559129,DB00818,10039906,28,1392,36,1641,0.800347336,0.916902427,0.535987691,1.554035471,0.892049316,DB0081810039906_,0.114233861,-0.086754217,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,propofol,DB00818
,559285,DB14513,10019063,21,7156,31,3533,9.44280224965385e-05,0.334486934,0.182393752,0.601995629,0.000758802,DB1451310019063_,7.183769995,-1.095157461,male,10019063,Hallucination,10037175,Psychiatric disorders,Psych,magnesium,DB14513
,559286,DB00087,10033371,48,1321,19,728,0.244811811,1.392039779,0.79599531,2.527964268,0.403568207,DB0008710033371_,0.907409766,0.330770138,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,alemtuzumab,DB00087
,559290,DB00338,10061920,21,33653,33,22239,0.001951877,0.420533425,0.231157137,0.749086692,0.009546023,DB0033810061920_,4.651630688,-0.866231315,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,omeprazole,DB00338
,559410,DB06262,10031127,72,3728,108,4206,0.069721421,0.752173552,0.54844642,1.026491225,0.160806173,DB0626210031127_,1.827555532,-0.284788194,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,droxidopa,DB06262
,559565,DB05351,10038435,126,2597,92,1039,3.22119095422363e-05,0.548055506,0.411345611,0.732263444,0.00030212,DB0535110038435_,8.104687754,-0.601378709,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,dexlansoprazole,DB05351
,559624,DB00820,10017367,40,11875,16,5800,0.569921119,1.221013724,0.668032566,2.337548573,0.720730172,DB0082010017367_,0.327490453,0.199681435,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,tadalafil,DB00820
,559625,DB08932,10017367,38,19405,12,6585,1,1.074590899,0.549308441,2.260145822,1,DB0893210017367_,0,0.07194003,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,559854,DB08932,10045555,61,19382,22,6575,0.800879544,0.940595637,0.568828127,1.609993817,0.892336857,DB0893210045555_,0.113911575,-0.061241948,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,559969,DB08820,10000059,32,4369,28,3517,0.794891201,0.919998357,0.53544077,1.589191583,0.88886732,DB0882010000059_,0.117807301,-0.083383395,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ivacaftor,DB08820
,559978,DB09183,10003549,24,451,40,687,0.793539484,0.914019573,0.519443627,1.578044575,0.888035819,DB0918310003549_,0.1187432,-0.089903293,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,dasabuvir,DB09183
,559980,DB09183,10013968,33,442,26,701,0.009416362,2.01178667,1.149466446,3.554358844,0.03392394,DB0918310013968_,3.383634332,0.699023218,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dasabuvir,DB09183
,560065,DB00455,10023232,83,9318,24,5094,0.005820812,1.890539545,1.186421318,3.118605303,0.023108298,DB0045510023232_,3.767563512,0.636862262,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,loratadine,DB00455
,560076,DB06273,10028411,49,5046,9,1401,0.335866491,1.511520699,0.732436127,3.509108829,0.504990889,DB0627310028411_,0.683214891,0.41311623,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,tocilizumab,DB06273
,560358,DB09027,10013781,24,5155,50,7102,0.09921111,0.661313968,0.388154554,1.098117298,0.209647367,DB0902710013781_,1.562328364,-0.413526563,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,ledipasvir,DB09027
,560893,DB08932,10033645,40,19403,13,6584,1,1.044117674,0.546638804,2.128975961,1,DB0893210033645_,0,0.043172198,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,561327,DB06262,10047895,35,3765,32,4282,0.391470352,1.243903034,0.746333141,2.079833594,0.561325586,DB0626210047895_,0.577454175,0.218254044,NA,10047895,Weight decreased,10022891,Investigations,Inv,droxidopa,DB06262
,562116,DB00341,10017955,39,11366,27,5041,0.08221474,0.640652551,0.381818803,1.089563915,0.182018483,DB0034110017955_,1.703647041,-0.445268012,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,cetirizine,DB00341
,563128,DB00009,10047289,20,1331,72,1479,6.76153593423636e-07,0.308801151,0.177146386,0.515900368,1.01326665924403e-05,DB0000910047289_,11.49974604,-1.175057734,male,10047289,Ventricular extrasystoles,10007541,Cardiac disorders,Card,alteplase,DB00009
,563859,DB01137,10057668,34,7738,25,5568,1,0.978603789,0.566170698,1.713020532,1,DB0113710057668_,0,-0.021628428,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,564237,DB00005,10012587,101,127981,68,42351,1.07541944679555e-05,0.491491511,0.357799342,0.678804992,0.000115586,DB0000510012587_,9.065499697,-0.710310611,NA,10012587,Device leakage,10077536,Product issues,Prod,etanercept,DB00005
,564322,DB08881,10003239,67,556,67,744,0.11972257,1.337837908,0.921816974,1.941736059,0.240970273,DB0888110003239_,1.4230817,0.291054809,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,vemurafenib,DB08881
,564584,DB00571,10006451,42,5081,9,2600,0.016520381,2.387755135,1.143393633,5.587737962,0.053133748,DB0057110006451_,2.934943002,0.870353651,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,propranolol,DB00571
,564693,DB00678,10033647,34,15565,24,10700,1,0.973862228,0.560396718,1.717499183,1,DB0067810033647_,0,-0.026485435,NA,10033647,Pancreatitis acute,10017947,Gastrointestinal disorders,Gastr,losartan,DB00678
,565341,DB00804,10000059,44,2956,8,891,0.244943985,1.657579808,0.768134815,4.091769628,0.403737098,DB0080410000059_,0.906991362,0.505358592,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,dicyclomine,DB00804
,565934,DB00207,10064848,121,8959,66,5389,0.544071467,1.102791435,0.808744371,1.515006461,0.69915757,DB0020710064848_,0.35787914,0.097844633,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,azithromycin,DB00207
,565937,DB01098,10064848,84,8065,48,7161,0.017715246,1.553795043,1.075547985,2.267150513,0.056179675,DB0109810064848_,2.879200239,0.440700353,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,rosuvastatin,DB01098
,566065,DB01065,10013700,58,4273,18,3033,0.00146814,2.28690271,1.325123856,4.133371367,0.007555566,DB0106510013700_,4.885470757,0.827198374,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,melatonin,DB01065
,566597,DB00465,10037660,45,2059,20,863,0.890739716,0.943074769,0.541841445,1.69651442,0.954680373,DB0046510037660_,0.046378682,-0.058609711,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ketorolac,DB00465
,566839,DB08895,10028035,60,28054,14,6632,1,1.013148938,0.559154241,1.964468555,1,DB0889510028035_,0,0.013063241,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,567020,DB00758,10028224,62,8238,73,10001,0.86266183,1.031084984,0.721981947,1.468622927,0.936336136,DB0075810028224_,0.065780747,0.03061163,NA,10028224,Multiple injuries,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,567251,DB00341,10025256,32,11373,19,5049,0.361556621,0.74769376,0.410671956,1.397611631,0.531398798,DB0034110025256_,0.632242507,-0.290761797,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,cetirizine,DB00341
,567346,DB00374,10013950,56,17660,12,5712,0.257043016,1.509340734,0.799037274,3.096032479,0.417912607,DB0037410013950_,0.872482942,0.411672955,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,567855,DB08895,10021688,74,28040,13,6633,0.411965771,1.346528563,0.740532433,2.648798316,0.581412672,DB0889510021688_,0.542294496,0.297529846,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,tofacitinib,DB08895
,567890,DB00046,10054112,65,5394,69,4623,0.223188248,0.807398658,0.565016739,1.152583574,0.377449129,DB0004610054112_,0.974319477,-0.213937733,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,insulin lispro,DB00046
,567893,DB00230,10054112,74,19600,40,8611,0.308364564,0.812803085,0.545521704,1.226899945,0.475638905,DB0023010054112_,0.743096316,-0.207266407,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,pregabalin,DB00230
,567895,DB00285,10054112,64,10887,33,3685,0.060096601,0.656461338,0.42407428,1.033472805,0.143655798,DB0028510054112_,1.940335131,-0.420891477,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,venlafaxine,DB00285
,567897,DB00332,10054112,54,2630,24,1632,0.196372337,1.396094727,0.844535826,2.371269428,0.344612827,DB0033210054112_,1.065333731,0.333678858,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,ipratropium,DB00332
,567898,DB01060,10054112,84,8503,54,5027,0.658320569,0.919656193,0.644469081,1.322036516,0.791309302,DB0106010054112_,0.234066362,-0.083755382,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,amoxicillin,DB01060
,568055,DB00158,10042609,167,16648,47,8057,0.000724493,1.719575843,1.235950752,2.433078623,0.004212763,DB0015810042609_,5.469636541,0.542077657,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,folic acid,DB00158
,568774,DB00331,10065154,142,24804,94,20658,0.088457464,1.25812691,0.962032579,1.651746563,0.192658943,DB0033110065154_,1.646833789,0.229624036,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,metformin,DB00331
,568775,DB00338,10065154,227,33447,99,22173,0.000423853,1.520038156,1.194449685,1.946018889,0.002687897,DB0033810065154_,5.918996246,0.418735437,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,omeprazole,DB00338
,568867,DB00321,10064848,58,7389,23,2827,0.900912722,0.96480841,0.584656603,1.642246535,0.956813906,DB0032110064848_,0.044146362,-0.035825737,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,amitriptyline,DB00321
,568870,DB00727,10064848,41,3802,27,4146,0.050433128,1.655793895,0.992164364,2.80500601,0.12580164,DB0072710064848_,2.073048897,0.504280589,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,nitroglycerin,DB00727
,569160,DB08932,10060933,238,19205,80,6517,1,1.009533858,0.779199455,1.319559704,1,DB0893210060933_,0,0.009488697,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,569401,DB00524,10003239,36,1541,22,1322,0.232668456,1.403648078,0.799076493,2.518015072,0.389137845,DB0052410003239_,0.943821642,0.339074617,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,metolazone,DB00524
,569451,DB00028,10058049,39,13419,14,5601,0.762949165,1.162722845,0.617031523,2.320284799,0.868725595,DB0002810058049_,0.140727975,0.150764535,NA,10058049,Administration site pain,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,569465,DB00028,10074796,43,13415,10,5605,0.09803569,1.796560013,0.888201984,4.011959756,0.207920936,DB0002810074796_,1.570597387,0.585873733,NA,10074796,Administration site erythema,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,569842,DB00374,10022687,36,17680,15,5709,0.415301118,0.774986458,0.413484399,1.524746671,0.584550584,DB0037410022687_,0.53691196,-0.254909724,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,treprostinil,DB00374
,569980,DB00169,10036495,68,38623,13,18162,0.001746522,2.459673275,1.34627728,4.855339797,0.008693793,DB0016910036495_,4.745145922,0.900028526,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,570020,DB01281,10061623,98,8834,15,1783,0.375789288,1.318614496,0.759444367,2.451373334,0.545595554,DB0128110061623_,0.605877321,0.276581561,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,570037,DB00999,10067482,87,21343,36,12203,0.110548635,1.381732198,0.926293132,2.099568546,0.226880412,DB0099910067482_,1.48333222,0.323337928,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,570154,DB11065,10035664,128,3058,118,2570,0.513372529,0.911655406,0.700281827,1.187644604,0.673343833,DB1106510035664_,0.395499183,-0.092493204,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pancrelipase amylase,DB11065
,570161,DB08895,10062060,45,28069,10,6636,1,1.063902842,0.52822073,2.368820456,1,DB0889510062060_,0,0.061944073,NA,10062060,Hyperlipidaemia,10027433,Metabolism and nutrition disorders,Metab,tofacitinib,DB08895
,570329,DB08904,10011224,133,11477,22,3537,0.005513612,1.862954568,1.178611173,3.07795071,0.02212262,DB0890410011224_,3.811154658,0.622163705,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,certolizumab pegol,DB08904
,570393,DB08932,10047943,52,19391,18,6579,0.891499379,0.98014547,0.563484819,1.781598071,0.954929174,DB0893210047943_,0.046118104,-0.02005428,NA,10047943,White blood cell count increased,10022891,Investigations,Inv,macitentan,DB08932
,571344,DB08932,10013578,87,19356,32,6565,0.673738376,0.922116931,0.607806845,1.43102292,0.802138219,DB0893210013578_,0.220474343,-0.081083241,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,571479,DB00028,10022062,40,13418,16,5599,1,1.043165428,0.570757714,1.997087531,1,DB0002810022062_,0,0.042259772,NA,10022062,Injection site extravasation,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,571630,DB00343,10056819,38,8698,12,5083,0.07682106,1.850483142,0.945547719,3.893550665,0.172887673,DB0034310056819_,1.755113186,0.615446763,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,diltiazem,DB00343
,571643,DB06605,10056819,36,14037,30,13003,0.712360417,1.11158613,0.665252566,1.869717259,0.828937505,DB0660510056819_,0.187610513,0.105787942,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,571707,DB00745,10010774,39,2538,13,1070,0.542009998,1.264672434,0.657649437,2.593039352,0.697309618,DB0074510010774_,0.360525751,0.234813143,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,modafinil,DB00745
,571777,DB01136,10037153,65,9819,67,11048,0.662090174,1.091571832,0.763002855,1.560850932,0.79398865,DB0113610037153_,0.230686112,0.087618705,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,carvedilol,DB01136
,571843,DB08906,10013573,79,2114,29,1129,0.099567791,1.454696182,0.933120741,2.324613342,0.210127611,DB0890610013573_,1.560040263,0.374797069,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,fluticasone furoate,DB08906
,572046,DB00051,10046851,39,25692,14,11406,0.553783117,1.236693726,0.656593545,2.466847715,0.707332194,DB0005110046851_,0.346254859,0.212441469,NA,10046851,Uveitis,10015919,Eye disorders,Eye,adalimumab,DB00051
,572075,DB12001,10012735,426,1200,6,50,0.007655446,2.957155791,1.254718466,8.500522167,0.028756469,DB1200110012735_,3.548892536,1.084227925,female,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,abemaciclib,DB12001
,572136,DB00531,10002948,28,7224,46,6470,0.013691575,0.545192596,0.327754866,0.892118328,0.045737186,DB0053110002948_,3.084843618,-0.60661616,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,cyclophosphamide,DB00531
,572140,DB01073,10002948,19,1046,34,1616,0.671464818,0.863421074,0.46259263,1.566744612,0.800664719,DB0107310002948_,0.222312998,-0.146852788,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,fludarabine,DB01073
,572298,DB09073,10051398,143,20117,8,782,0.281654515,0.694872201,0.341604157,1.646455664,0.44561886,DB0907310051398_,0.808291265,-0.364027333,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,palbociclib,DB09073
,572329,DB09073,10061818,946,19314,34,756,0.730290946,1.08908361,0.766917483,1.594270807,0.843097434,DB0907310061818_,0.170672747,0.085336617,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,palbociclib,DB09073
,572445,DB06262,10000081,50,3750,10,4304,5.71736581217108e-09,5.737217201,2.870657083,12.70774696,1.35632635715629e-07,DB0626210000081_,15.81331581,1.746974285,female,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,droxidopa,DB06262
,572495,DB06589,10076309,43,1987,34,2619,0.027686582,1.666750943,1.034054723,2.705951431,0.079543317,DB0658910076309_,2.531453534,0.510876188,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pazopanib,DB06589
,572511,DB00526,10003225,36,1562,52,1842,0.386861931,0.816456617,0.515592455,1.280448055,0.556943031,DB0052610003225_,0.585292323,-0.202781501,NA,10003225,Arteriospasm coronary,10007541,Cardiac disorders,Card,oxaliplatin,DB00526
,572512,DB00544,10003225,39,2396,60,2593,0.103717093,0.703493513,0.455803926,1.074833095,0.216571638,DB0054410003225_,1.529833895,-0.351696624,NA,10003225,Arteriospasm coronary,10007541,Cardiac disorders,Card,fluorouracil,DB00544
,572513,DB00650,10003225,36,2095,47,1967,0.14993166,0.719220195,0.450529699,1.139596082,0.283828303,DB0065010003225_,1.259385791,-0.329587716,NA,10003225,Arteriospasm coronary,10007541,Cardiac disorders,Card,leucovorin,DB00650
,572561,DB00490,10040047,38,4032,12,1564,0.635707757,1.228284657,0.626319276,2.589010127,0.77357991,DB0049010040047_,0.256726304,0.205618609,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,buspirone,DB00490
,572574,DB00490,10069339,58,4012,20,1556,0.704678935,1.124700285,0.66384868,1.981134588,0.822904333,DB0049010069339_,0.194915327,0.117516586,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,buspirone,DB00490
,573524,DB00567,10028810,51,4468,23,2058,1,1.021361141,0.611010539,1.756207483,1,DB0056710028810_,0,0.02113619,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,cephalexin,DB00567
,573626,DB01268,10028810,25,2118,31,3099,0.58508798,1.179934966,0.66588227,2.071528077,0.732666566,DB0126810028810_,0.31106457,0.165459323,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,sunitinib,DB01268
,574061,DB00761,10011781,71,15236,16,8609,0.000455571,2.50729424,1.441724121,4.624562446,0.002857052,DB0076110011781_,5.857964799,0.91920418,NA,10011781,Cystitis,10021881,Infections and infestations,Infec,potassium chloride,DB00761
,574123,DB00864,10066901,29,6840,44,8348,0.409740228,0.804411242,0.484794519,1.316385531,0.579173558,DB0086410066901_,0.546153091,-0.217644646,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,574302,DB14513,10016825,42,7135,15,3549,0.323957976,1.392707501,0.755427754,2.707507211,0.492380906,DB1451310016825_,0.708502663,0.331249695,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,magnesium,DB14513
,574396,DB00656,10013663,33,11980,25,6594,0.271272991,0.726589645,0.41868425,1.275667198,0.434027292,DB0065610013663_,0.834647863,-0.319393411,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,trazodone,DB00656
,574434,DB00996,10012239,24,38929,36,22389,0.000242767,0.383420653,0.218786693,0.66083138,0.001691937,DB0099610012239_,6.381881074,-0.958622581,NA,10012239,Delusion,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,574787,DB01156,10028735,52,13570,16,6312,0.153522293,1.511688145,0.848790427,2.838903138,0.28887324,DB0115610028735_,1.241767302,0.413227003,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,bupropion,DB01156
,574812,DB08931,10049848,48,6529,18,2428,1,0.991678962,0.565013362,1.815198934,1,DB0893110049848_,0,-0.008355851,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,574911,DB09033,10013709,135,2489,86,1583,1,0.998369893,0.750356448,1.334133391,1,DB0903310013709_,0,-0.001631437,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,vedolizumab,DB09033
,575128,DB00009,10047302,20,1331,68,1483,3.60516951393456e-06,0.327847111,0.187489556,0.549889821,4.44057547674649e-05,DB0000910047302_,10.02214149,-1.115207905,male,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,alteplase,DB00009
,575303,DB05259,10064355,43,11227,8,2720,0.596898416,1.302191631,0.604268162,3.210585107,0.742257829,DB0525910064355_,0.298058618,0.264048715,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,glatiramer,DB05259
,575838,DB06637,10011640,56,6106,6,2013,0.004509105,3.076793637,1.325479067,8.75206603,0.018802945,DB0663710011640_,3.973741771,1.123888028,female,10011640,Culture urine positive,10022891,Investigations,Inv,dalfampridine,DB06637
,576101,DB09270,10000087,41,3073,20,2348,0.118438894,1.566226705,0.894047809,2.829791802,0.238867976,DB0927010000087_,1.431844281,0.448669354,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ubidecarenone,DB09270
,576386,DB00368,10011906,26,634,37,761,0.605107721,0.843563058,0.484746647,1.448718905,0.748273008,DB0036810011906_,0.289987383,-0.170120622,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,norepinephrine,DB00368
,576390,DB00368,10040070,52,608,35,763,0.005455963,1.863640776,1.174114806,2.988847134,0.02192981,DB0036810040070_,3.819908358,0.622531981,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,norepinephrine,DB00368
,576534,DB01142,10016173,47,1693,20,764,0.894121666,1.060459269,0.611327952,1.90307589,0.955860142,DB0114210016173_,0.045143671,0.058702087,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,doxepin,DB01142
,576764,DB06210,10013709,79,1381,73,988,0.128042456,0.774313622,0.549952301,1.091308377,0.252881206,DB0621010013709_,1.374835443,-0.255778291,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,eltrombopag,DB06210
,577186,DB09035,10062767,38,4688,56,6634,0.916384819,0.960247033,0.617653019,1.47841128,0.962639876,DB0903510062767_,0.038075898,-0.040564702,NA,10062767,Hypophysitis,10014698,Endocrine disorders,Endo,nivolumab,DB09035
,577200,DB01611,10033318,40,11873,11,2350,0.343718961,0.719757933,0.361790337,1.557738135,0.512982789,DB0161110033318_,0.667512984,-0.328840328,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,hydroxychloroquine,DB01611
,577415,DB09570,10046571,50,3851,31,3904,0.033666657,1.634989357,1.021686351,2.653913164,0.092706309,DB0957010046571_,2.378318745,0.491636295,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ixazomib,DB09570
,577559,DB01592,10068319,49,6227,13,3054,0.056452164,1.84849191,0.985697006,3.719925942,0.136892123,DB0159210068319_,1.988562088,0.614370123,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,iron,DB01592
,577561,DB00448,10037153,32,5113,20,3104,1,0.971313423,0.537654055,1.795363349,1,DB0044810037153_,0,-0.02910608,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,lansoprazole,DB00448
,578015,DB00281,10047461,51,11407,23,5648,0.804734561,1.097898121,0.658122983,1.884287599,0.894427482,DB0028110047461_,0.11157145,0.093397553,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,lidocaine,DB00281
,578283,DB08820,10013709,40,4361,28,3517,0.62489517,1.152064511,0.691703209,1.943293325,0.764521844,DB0882010013709_,0.268504681,0.14155556,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ivacaftor,DB08820
,578495,DB00480,10053459,32,67396,18,67644,0.048460891,1.78430086,0.971702548,3.376842928,0.122198247,DB0048010053459_,2.10211058,0.579026664,NA,10053459,Secretion discharge,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,578604,DB00338,10039897,42,33632,28,22244,1,0.992089792,0.600415393,1.662504248,1,DB0033810039897_,0,-0.007941659,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,578799,DB00193,10054236,52,19268,27,8675,0.544271849,0.867120953,0.534342496,1.436952027,0.699312504,DB0019310054236_,0.357657564,-0.142576804,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,tramadol,DB00193
,578995,DB01076,10041232,31,25716,26,25557,0.596544238,1.184930488,0.68063606,2.078398134,0.741940253,DB0107610041232_,0.298486561,0.169684113,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atorvastatin,DB01076
,579508,DB00338,10037876,39,33635,19,22253,0.286682861,1.358018312,0.76583213,2.488664887,0.451441349,DB0033810037876_,0.795309818,0.306026513,NA,10037876,Rash papular,10040785,Skin and subcutaneous tissue disorders,Skin,omeprazole,DB00338
,579835,DB06262,10061428,22,3778,37,4277,0.15120306,0.67316302,0.377525655,1.173911747,0.285547263,DB0626210061428_,1.253347718,-0.39576775,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,droxidopa,DB06262
,579982,DB00868,10020772,38,2946,13,1633,0.143203301,1.620137282,0.841246524,3.324465733,0.274331226,DB0086810020772_,1.293419047,0.482510888,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,benzonatate,DB00868
,580154,DB00656,10048010,80,11933,27,6592,0.025795474,1.636752613,1.045203695,2.637425299,0.075240974,DB0065610048010_,2.587059328,0.492714165,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,580875,DB00003,10021789,163,2835,124,2469,0.274647025,1.144783316,0.894901635,1.467257057,0.437919142,DB0000310021789_,0.825720994,0.135215375,NA,10021789,Infection,10021881,Infections and infestations,Infec,dornase alfa,DB00003
,580876,DB11065,10021789,107,3079,84,2604,0.657948687,1.07731101,0.797930501,1.458379822,0.790952721,DB1106510021789_,0.234517084,0.074468131,NA,10021789,Infection,10021881,Infections and infestations,Infec,pancrelipase amylase,DB11065
,580957,DB00115,10037162,90,18335,16,10456,2.12717944700993e-06,3.207687339,1.870515059,5.853937947,2.79774389615492e-05,DB0011510037162_,10.48411212,1.165550222,female,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,cyanocobalamin,DB00115
,580958,DB00425,10037162,55,12640,17,7467,0.019655506,1.911171753,1.091774958,3.51515829,0.060975449,DB0042510037162_,2.797283974,0.647716537,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,zolpidem,DB00425
,581000,DB04951,10000081,27,1855,30,3027,0.169951507,1.468459403,0.837092876,2.564880625,0.310846521,DB0495110000081_,1.16845599,0.384213826,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,pirfenidone,DB04951
,581022,DB01115,10022000,47,3553,14,2254,0.01163494,2.129498653,1.149395447,4.198168722,0.040173977,DB0111510022000_,3.214535832,0.755886578,NA,10022000,Influenza,10021881,Infections and infestations,Infec,nifedipine,DB01115
,581148,DB09079,10011224,43,614,31,846,0.007817629,1.91034741,1.16115738,3.175097667,0.029234085,DB0907910011224_,3.53241994,0.647285115,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nintedanib,DB09079
,581324,DB00868,10022000,73,2911,28,1618,0.114478574,1.448999591,0.921128572,2.337523955,0.232851482,DB0086810022000_,1.457354443,0.370873381,NA,10022000,Influenza,10021881,Infections and infestations,Infec,benzonatate,DB00868
,581374,DB09078,10012735,125,668,215,841,0.01282771,0.732090669,0.569139262,0.93897436,0.043430972,DB0907810012735_,3.136582447,-0.311850909,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lenvatinib,DB09078
,581430,DB08906,10006451,50,2143,13,1145,0.022190592,2.054603536,1.093904068,4.140497389,0.067055206,DB0890610006451_,2.702239028,0.720082903,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,fluticasone furoate,DB08906
,581576,DB01611,10042609,71,11842,15,2346,0.771985879,0.937705507,0.53096231,1.765783457,0.875164899,DB0161110042609_,0.133342955,-0.064319338,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,hydroxychloroquine,DB01611
,581628,DB00264,10037876,23,29584,31,24861,0.100428359,0.623500685,0.347075609,1.104870595,0.21146835,DB0026410037876_,1.553679939,-0.472405416,NA,10037876,Rash papular,10040785,Skin and subcutaneous tissue disorders,Skin,metoprolol,DB00264
,581632,DB06643,10042609,62,52359,6,7509,0.463376427,1.481932677,0.643287256,4.194403987,0.630557536,DB0664310042609_,0.461150873,0.393347099,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,denosumab,DB06643
,581816,DB00368,10070863,53,607,52,746,0.308834598,1.252427781,0.824802522,1.90259925,0.476154349,DB0036810070863_,0.742013215,0.225083892,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,norepinephrine,DB00368
,581830,DB00635,10006105,19,33034,38,23756,0.000219357,0.359574499,0.195725337,0.639556415,0.001557275,DB0063510006105_,6.464817586,-1.022833895,male,10006105,Brain abscess,10021881,Infections and infestations,Infec,prednisone,DB00635
,582176,DB05679,10020937,41,6890,24,4885,0.528401833,1.211177484,0.713604977,2.098678459,0.685783201,DB0567910020937_,0.377193734,0.191593014,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,ustekinumab,DB05679
,582178,DB05679,10033775,52,6879,20,4889,0.021972905,1.847758803,1.082775357,3.272099784,0.066565759,DB0567910033775_,2.709564959,0.613973447,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,ustekinumab,DB05679
,582519,DB06605,10036790,62,14011,36,12997,0.025791806,1.597548328,1.042124221,2.4821436,0.07523445,DB0660510036790_,2.587146047,0.468470159,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,582707,DB00338,10015137,39,33635,24,22248,0.89766014,1.074872572,0.630154026,1.869104481,0.956338178,DB0033810015137_,0.044643686,0.072202116,NA,10015137,Eructation,10017947,Gastrointestinal disorders,Gastr,omeprazole,DB00338
,582732,DB00818,10013983,21,1399,30,1647,0.571662634,0.82414026,0.446287741,1.495779963,0.721786547,DB0081810013983_,0.326025826,-0.193414546,NA,10013983,Dystonia,10029205,Nervous system disorders,Nerv,propofol,DB00818
,582793,DB00787,10061225,34,16966,39,17209,0.640258628,0.884285011,0.541192745,1.438462044,0.777258362,DB0078710061225_,0.251982472,-0.122975858,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,582994,DB06655,10003549,34,3654,32,2087,0.052908068,0.606937048,0.362189867,1.019165803,0.13050756,DB0665510003549_,2.036324121,-0.499330203,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,liraglutide,DB06655
,583033,DB08895,10052251,47,28067,12,6634,0.742976184,0.925744113,0.483195946,1.918396828,0.852893503,DB0889510052251_,0.159120589,-0.077157418,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,583035,DB01097,10061623,108,6157,22,1481,0.575352202,1.180803637,0.738451204,1.969181891,0.724791289,DB0109710061623_,0.321871543,0.166195255,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,583461,DB08904,10054236,43,11567,19,3540,0.17872089,0.692642439,0.394484396,1.260244245,0.322266487,DB0890410054236_,1.132376475,-0.367241374,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,certolizumab pegol,DB08904
,583992,DB01222,10052904,47,9227,13,5392,0.015286452,2.112631196,1.123263238,4.260343949,0.050056607,DB0122210052904_,2.994600784,0.747934183,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,budesonide,DB01222
,584168,DB00924,10031009,48,10114,7,4244,0.004652455,2.877057249,1.293039877,7.543249957,0.019291653,DB0092410031009_,3.948082768,1.056767983,female,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,cyclobenzaprine,DB00924
,584580,DB00787,10018651,19,16981,33,17215,0.070563211,0.583703945,0.313445022,1.05751403,0.16229909,DB0078710018651_,1.818314412,-0.538361369,NA,10018651,Graft versus host disease,10021428,Immune system disorders,Immun,acyclovir,DB00787
,584853,DB01006,10013968,278,5669,9,168,0.718713947,0.915419666,0.464068913,2.058808388,0.833909953,DB0100610013968_,0.181629852,-0.088372667,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,letrozole,DB01006
,585217,DB00415,10071404,22,764,30,512,0.014030823,0.491711179,0.267024798,0.89261256,0.046671976,DB0041510071404_,3.064611389,-0.70986377,NA,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,ampicillin,DB00415
,586682,DB00541,10020578,35,3099,49,4248,1,0.97911904,0.614213842,1.546132125,1,DB0054110020578_,0,-0.02110205,NA,10020578,Hyperbilirubinaemia,10019805,Hepatobiliary disorders,Hepat,vincristine,DB00541
,589460,DB00537,10027175,50,7507,14,4284,0.018280021,2.037987164,1.107643733,3.996865654,0.057543151,DB0053710027175_,2.855220158,0.711962636,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ciprofloxacin,DB00537
,590373,DB00959,10013781,43,8035,10,4992,0.002839375,2.671322492,1.320266236,5.967488684,0.012925696,DB0095910013781_,4.348538037,0.982573665,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,595676,DB00864,10047571,41,6828,24,8368,0.003851875,2.093552029,1.233911447,3.626311357,0.016544904,DB0086410047571_,4.101677152,0.738862159,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,tacrolimus,DB00864
,596441,DB00996,10038776,45,38908,13,22412,0.028371713,1.99391181,1.05677064,4.029827526,0.081099503,DB0099610038776_,2.512078441,0.690098443,NA,10038776,Retching,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,596464,DB00203,10041232,45,13833,12,8926,0.004228864,2.419664541,1.258008838,5.027714494,0.017869252,DB0020310041232_,4.024673795,0.883628911,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sildenafil,DB00203
,596479,DB00996,10041232,45,38908,16,22409,0.110175204,1.619842227,0.897916906,3.070988069,0.226308383,DB0099610041232_,1.485856682,0.482328754,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,gabapentin,DB00996
,596735,DB09035,10014625,31,4695,51,6639,0.574133093,0.859557378,0.530760884,1.371635246,0.723950889,DB0903510014625_,0.323031722,-0.151337699,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,nivolumab,DB09035
,597523,DB08895,10019303,81,28033,8,6638,0.014295473,2.397506121,1.159791535,5.744784624,0.047384177,DB0889510019303_,3.049466932,0.874429081,NA,10019303,Heart rate increased,10022891,Investigations,Inv,tofacitinib,DB08895
,597548,DB01156,10022052,46,13576,9,6319,0.013260679,2.378899945,1.149555101,5.531362527,0.044569504,DB0115610022052_,3.110705429,0.866638173,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,bupropion,DB01156
,597723,DB08931,10037377,67,6510,25,2421,1,0.996663946,0.619465237,1.651138229,1,DB0893110037377_,0,-0.003341631,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,598180,DB08895,10067484,114,28000,26,6620,1,1.036656481,0.671719508,1.65562534,1,DB0889510067484_,0,0.036000612,NA,10067484,Adverse reaction,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,598709,DB08895,10060933,88,28026,18,6628,0.710252579,1.156190964,0.690233055,2.042074781,0.827193699,DB0889510060933_,0.189716393,0.145130951,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,599600,DB00230,10017062,41,19633,11,8640,0.174588738,1.640255144,0.827509403,3.540363884,0.316902492,DB0023010017062_,1.14916115,0.494851805,NA,10017062,Formication,10029205,Nervous system disorders,Nerv,pregabalin,DB00230
,600407,DB08895,10039227,60,28054,10,6636,0.362488685,1.419243631,0.720333444,3.111586886,0.53216466,DB0889510039227_,0.630802325,0.350124075,NA,10039227,Rotator cuff syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,600414,DB08895,10043255,50,28064,7,6639,0.237672897,1.689722682,0.761982672,4.420121168,0.395144345,DB0889510043255_,0.92850415,0.524564422,NA,10043255,Tendonitis,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,600900,DB08931,10028372,58,6519,27,2419,0.328405273,0.797114302,0.49542955,1.312510512,0.496985008,DB0893110028372_,0.699195418,-0.226757196,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,riociguat,DB08931
,601729,DB00635,10017543,18,33035,37,23757,0.000173479,0.349860707,0.187442947,0.630472354,0.001279251,DB0063510017543_,6.661480518,-1.050220184,male,10017543,Fungal skin infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,601970,DB08931,10043071,69,6508,20,2426,0.401267058,1.286010564,0.770450465,2.239217438,0.571096983,DB0893110043071_,0.560196237,0.25154484,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,riociguat,DB08931
,602220,DB00126,10065154,52,10119,29,5916,0.908321626,1.048325442,0.652478496,1.714695541,0.958996855,DB0012610065154_,0.041867483,0.047194073,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,ascorbic acid,DB00126
,602560,DB00254,10070608,33,5902,31,3357,0.050162833,0.605490164,0.358783604,1.024297477,0.125323646,DB0025410070608_,2.076855723,-0.501716961,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,doxycycline,DB00254
,603070,DB00338,10071134,33,33641,22,22250,1,0.992091909,0.561172496,1.786586556,1,DB0033810071134_,0,-0.007939526,NA,10071134,Product physical issue,10077536,Product issues,Prod,omeprazole,DB00338
,603160,DB00669,10063829,168,6209,34,1063,0.365193239,0.845982914,0.578579937,1.269209817,0.534843532,DB0066910063829_,0.625781038,-0.167256116,NA,10063829,Device malfunction,10077536,Product issues,Prod,sumatriptan,DB00669
,603196,DB00065,10064774,48,9416,44,4913,0.007998582,0.569205238,0.369584706,0.878603148,0.029774378,DB0006510064774_,3.514107064,-0.563514211,NA,10064774,Infusion site extravasation,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,603286,DB01377,10000087,51,3745,22,2648,0.055822875,1.639008964,0.97352768,2.845370355,0.135760943,DB0137710000087_,1.996859712,0.494091769,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,magnesium oxide,DB01377
,604144,DB00230,10061394,69,19605,16,8635,0.018114051,1.899398222,1.090205458,3.508347968,0.057127341,DB0023010061394_,2.86247245,0.641537111,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,604260,DB00915,10048959,41,1414,34,1017,0.554439835,0.867366446,0.532896672,1.419901713,0.707964589,DB0091510048959_,0.345361202,-0.142293732,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,amantadine,DB00915
,604297,DB01264,10037844,17,373,34,717,1,0.961157211,0.496538243,1.796285645,1,DB0126410037844_,0,-0.039617292,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,darunavir,DB01264
,604835,DB08895,10022611,76,28038,12,6634,0.222255248,1.498489469,0.809315517,3.029013341,0.37635556,DB0889510022611_,0.977220943,0.40445758,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,605245,DB05812,10053762,13,169,110,7843,3.28801475988885e-06,5.481106069,2.773110984,10.01726983,4.09987988442498e-05,DB0581210053762_,10.10196779,1.701306918,female,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,abiraterone,DB05812
,605479,DB00734,10069218,121,3929,163,4739,0.396424415,0.895399669,0.699042708,1.144359118,0.566027084,DB0073410069218_,0.56911335,-0.110485102,NA,10069218,Syringe issue,10077536,Product issues,Prod,risperidone,DB00734
,605634,DB08907,10059896,28,4225,54,3856,0.001178526,0.473278442,0.288026036,0.762235886,0.006307146,DB0890710059896_,5.066071977,-0.748071391,NA,10059896,Urine output increased,10022891,Investigations,Inv,canagliflozin,DB08907
,605649,DB00734,10071134,25,4025,41,4861,0.264249397,0.736429412,0.428369124,1.242708395,0.426161634,DB0073410071134_,0.852936582,-0.305941891,NA,10071134,Product physical issue,10077536,Product issues,Prod,risperidone,DB00734
,605658,DB00273,10047340,47,8434,8,2185,0.317984696,1.521970862,0.711173282,3.734924444,0.485943474,DB0027310047340_,0.721662971,0.420006115,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,topiramate,DB00273
,605667,DB05679,10022004,39,6892,21,4888,0.358425452,1.317107254,0.754925483,2.359791641,0.528154109,DB0567910022004_,0.638367165,0.275437858,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,605686,DB05679,10001760,118,6813,19,4890,2.49897650946618e-12,4.457112123,2.726857791,7.675856471,1.05434345989275e-10,DB0567910001760_,22.97293267,1.49450105,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,ustekinumab,DB05679
,605690,DB05679,10063829,51,6880,46,4863,0.255153179,0.783684876,0.514747621,1.196007547,0.415854988,DB0567910063829_,0.877418666,-0.243748284,NA,10063829,Device malfunction,10077536,Product issues,Prod,ustekinumab,DB05679
,605771,DB00620,10047571,42,4786,26,3106,0.901266476,1.048344938,0.626485,1.785021615,0.956927891,DB0062010047571_,0.044027239,0.047212671,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,triamcinolone,DB00620
,605780,DB05679,10069218,124,6807,94,4815,0.627606952,0.933119192,0.706060673,1.236586998,0.767018423,DB0567910069218_,0.265244458,-0.069222335,NA,10069218,Syringe issue,10077536,Product issues,Prod,ustekinumab,DB05679
,605783,DB05679,10073317,83,6848,30,4879,0.001058031,1.971053616,1.281794946,3.105984305,0.005774574,DB0567910073317_,5.15429084,0.67856823,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,ustekinumab,DB05679
,605818,DB05679,10064355,69,6862,46,4863,0.776164557,1.063033436,0.720108743,1.582046067,0.877974152,DB0567910064355_,0.130138125,0.061126553,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,ustekinumab,DB05679
,605951,DB00734,10069217,47,4003,74,4828,0.168106911,0.766057032,0.518537695,1.121950275,0.308283988,DB0073410069217_,1.176733883,-0.266498657,NA,10069217,Needle issue,10077536,Product issues,Prod,risperidone,DB00734
,605967,DB05679,10013573,76,6855,47,4862,0.519789769,1.146847085,0.785287211,1.690226988,0.678958111,DB0567910013573_,0.387195846,0.137016512,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ustekinumab,DB05679
,606050,DB05679,10069217,40,6891,31,4878,0.718263135,0.913401226,0.556342801,1.512458638,0.83360767,DB0567910069217_,0.181992407,-0.090580036,NA,10069217,Needle issue,10077536,Product issues,Prod,ustekinumab,DB05679
,606131,DB08907,10000059,20,4233,31,3879,0.068581001,0.591250388,0.318806075,1.072930031,0.158747005,DB0890710000059_,1.840443505,-0.525515683,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,canagliflozin,DB08907
,606699,DB00734,10073317,296,3754,117,4785,1.40339533876078e-28,3.224325179,2.582764751,4.046399816,2.84851324164687e-26,DB0073410073317_,58.82041523,1.170723682,female,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,606862,DB06791,10019211,66,713,33,505,0.13634516,1.416185228,0.903392738,2.256825599,0.264577352,DB0679110019211_,1.329621622,0.347966797,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lanreotide,DB06791
,606937,DB06791,10028813,94,685,35,503,0.000905811,1.971181829,1.299298305,3.047694392,0.005079302,DB0679110028813_,5.282581389,0.678633276,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lanreotide,DB06791
,607141,DB00275,10025476,76,1984,65,1172,0.033100274,0.690799192,0.485390366,0.98533351,0.091510519,DB0027510025476_,2.391301351,-0.369906102,NA,10025476,Malabsorption,10017947,Gastrointestinal disorders,Gastr,olmesartan,DB00275
,607143,DB00999,10025476,76,21354,47,12192,0.70735409,0.923236693,0.632981211,1.358961948,0.825063335,DB0099910025476_,0.192295126,-0.079869639,NA,10025476,Malabsorption,10017947,Gastrointestinal disorders,Gastr,hydrochlorothiazide,DB00999
,607283,DB01104,10013722,20,15443,31,7255,2.89658104203142e-05,0.303109344,0.163612657,0.549443137,0.000275028,DB0110410013722_,8.198638137,-1.193661667,male,10013722,Drug level increased,10022891,Investigations,Inv,sertraline,DB01104
,607686,DB00734,10057765,24,4026,34,4868,0.598107563,0.853526347,0.483391141,1.485012811,0.742999711,DB0073410057765_,0.297059623,-0.158378868,NA,10057765,Procedural complication,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,607766,DB00121,10027175,66,4157,16,452,0.007896685,0.448627526,0.254236293,0.837402643,0.029471015,DB0012110027175_,3.524348024,-0.801562299,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,biotin,DB00121
,609022,DB00059,10007515,32,795,24,1083,0.028854821,1.815742085,1.027402508,3.249127122,0.082164747,DB0005910007515_,2.499028935,0.596494247,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,pegaspargase,DB00059
,609110,DB01015,10070608,75,9812,62,9319,0.440906502,1.148888719,0.80867077,1.637306408,0.609154396,DB0101510070608_,0.49568352,0.138795144,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,609729,DB00065,10043417,30,9434,21,4936,0.304695638,0.747490649,0.413444914,1.37519431,0.471487643,DB0006510043417_,0.751862385,-0.291033483,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,609981,DB09073,10001760,1652,18608,9,781,3.89025803915405e-18,7.703692343,4.026666661,16.9502099,3.3915566354615e-16,DB0907310001760_,35.62007249,2.041699739,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,palbociclib,DB09073
,610275,DB09078,10020772,108,685,77,979,1.01351457836535e-05,2.00384819,1.457071081,2.765992523,0.000109902,DB0907810020772_,9.115922028,0.695069427,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,lenvatinib,DB09078
,610469,DB08893,10025482,60,2025,14,1044,0.005941192,2.209044957,1.212941719,4.301612563,0.023483603,DB0889310025482_,3.751452832,0.792560276,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,mirabegron,DB08893
,610761,DB00924,10054112,82,10080,25,4226,0.201139506,1.375044757,0.868132811,2.249920234,0.350349684,DB0092410054112_,1.048823526,0.318486281,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,cyclobenzaprine,DB00924
,611467,DB00190,10022437,101,3196,115,4559,0.107372545,1.252766456,0.945538822,1.657687734,0.222227351,DB0019010022437_,1.504054319,0.225354271,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,611561,DB00905,10064355,44,2674,8,917,0.108727198,1.88593121,0.873906101,4.656044683,0.224104638,DB0090510064355_,1.4956422,0.634421709,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,bimatoprost,DB00905
,611659,DB09029,10040753,256,11088,105,7165,8.31441503846916e-05,1.575444752,1.247982756,2.000589748,0.000681354,DB0902910040753_,7.291428088,0.454537615,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,secukinumab,DB09029
,611851,DB00065,10048737,40,9424,11,4946,0.055563008,1.908396875,0.959951747,4.127787063,0.135279147,DB0006510048737_,2.000414879,0.646263557,NA,10048737,Poor venous access,10047065,Vascular disorders,Vasc,infliximab,DB00065
,612058,DB09045,10013573,39,2310,28,1696,1,1.022630623,0.610633453,1.733025294,1,DB0904510013573_,0,0.022378349,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,dulaglutide,DB09045
,612059,DB09045,10013968,41,2308,30,1694,1,1.003089973,0.608424151,1.670997048,1,DB0904510013968_,0,0.003085209,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dulaglutide,DB09045
,612279,DB06674,10076309,61,4445,33,1457,0.02948647,0.605960549,0.388694155,0.959749407,0.083577061,DB0667410076309_,2.481986191,-0.500940395,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,golimumab,DB06674
,612280,DB06674,10057362,42,4464,19,1471,0.296192658,0.728465473,0.412922035,1.330629775,0.462042968,DB0667410057362_,0.772097387,-0.31681505,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,golimumab,DB06674
,612459,DB01373,10019063,77,22643,35,7346,0.099506605,0.713748238,0.472329981,1.097942103,0.210099696,DB0137310019063_,1.560173117,-0.337224986,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,calcium,DB01373
,612505,DB00635,10063829,62,32991,16,23778,0.000118431,2.79278075,1.591535472,5.187173368,0.00092127,DB0063510063829_,6.98975789,1.027037784,female,10063829,Device malfunction,10077536,Product issues,Prod,prednisone,DB00635
,612576,DB00541,10076309,27,3107,36,4261,0.898983087,1.028573045,0.599201722,1.746291746,0.956490275,DB0054110076309_,0.044484657,0.028172448,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,vincristine,DB00541
,612735,DB06674,10053762,178,4328,72,1418,0.1551804,0.809997833,0.608375793,1.087748032,0.291028991,DB0667410053762_,1.234332392,-0.210723706,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,golimumab,DB06674
,613076,DB06637,10062226,184,5978,13,2006,2.6125883992398e-11,4.749059216,2.701291107,9.107680506,9.33041930353508e-10,DB0663710062226_,20.79257097,1.557946539,female,10062226,Urine analysis abnormal,10022891,Investigations,Inv,dalfampridine,DB06637
,614873,DB00864,10051118,35,6834,23,8369,0.023840627,1.863438046,1.069258609,3.30653751,0.070864059,DB0086410051118_,2.646991904,0.622423193,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,614884,DB14512,10076309,72,4772,36,2376,1,0.995808889,0.656392447,1.534667043,1,DB1451210076309_,0,-0.004199918,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,mometasone furoate,DB14512
,614892,DB09027,10028334,45,5134,42,7110,0.080548158,1.483728874,0.950947027,2.31934851,0.179310467,DB0902710028334_,1.718636522,0.394558428,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ledipasvir,DB09027
,615091,DB00295,10035742,17,14646,33,9569,0.000216394,0.336590373,0.175753652,0.622298986,0.001539352,DB0029510035742_,6.476394014,-1.088888599,male,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,morphine,DB00295
,615377,DB00091,10069293,76,5434,14,2656,0.000389235,2.653086387,1.484833105,5.090997766,0.002507607,DB0009110069293_,5.988426489,0.975723636,NA,10069293,Product container issue,10077536,Product issues,Prod,cyclosporine,DB00091
,616140,DB09073,10003239,727,19533,7,783,3.93145444183952e-06,4.163059428,2.000498628,10.42765958,4.78528733520499e-05,DB0907310003239_,9.947379393,1.426250243,female,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,palbociclib,DB09073
,616143,DB09073,10029331,384,19876,6,784,0.015019415,2.5243767,1.143911663,6.943150325,0.049372852,DB0907310029331_,3.008354565,0.925994181,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,palbociclib,DB09073
,616144,DB09073,10061428,946,19314,10,780,3.04307239108559e-07,3.820298666,2.056756141,8.024915009,4.94970035889138e-06,DB0907310061428_,12.21618352,1.340328604,female,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,palbociclib,DB09073
,616232,DB08895,10021097,53,28061,16,6630,0.361351779,0.78265386,0.440264274,1.467744722,0.531226358,DB0889510021097_,0.632567063,-0.24506475,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,tofacitinib,DB08895
,616294,DB08895,10050296,49,28065,7,6639,0.23726671,1.655870857,0.745639153,4.335694739,0.394611792,DB0889510050296_,0.929852802,0.504327068,NA,10050296,Intervertebral disc protrusion,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,616586,DB01136,10017412,38,9846,29,11086,0.140746966,1.475329317,0.885380283,2.482225291,0.270879296,DB0113610017412_,1.306081958,0.388881231,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,carvedilol,DB01136
,616971,DB00704,10022004,49,4307,48,5146,0.3570147,1.219661105,0.800476326,1.85927333,0.526724933,DB0070410022004_,0.641076816,0.198573037,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,617405,DB06403,10037884,64,21407,19,6642,1,1.04515221,0.617671386,1.848753739,1,DB0640310037884_,0,0.044162531,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,ambrisentan,DB06403
,617911,DB00051,10065154,644,25087,281,11139,0.828662213,1.017609002,0.881563979,1.176970583,0.909933794,DB0005110065154_,0.094383436,0.01745576,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,adalimumab,DB00051
,617981,DB08904,10002556,44,11566,30,3529,0.00131042,0.447529889,0.274602093,0.738462727,0.006877188,DB0890410002556_,4.979545389,-0.804011953,NA,10002556,Ankylosing spondylitis,10028395,Musculoskeletal and connective tissue disorders,Musc,certolizumab pegol,DB08904
,618086,DB00668,10023683,37,10054,23,4280,0.158764255,0.684843027,0.395739225,1.20874022,0.295829472,DB0066810023683_,1.217972098,-0.378565625,NA,10023683,Lagophthalmos,10015919,Eye disorders,Eye,epinephrine,DB00668
,618356,DB09037,10038695,28,2498,38,2797,0.459386374,0.825069155,0.486146456,1.384831333,0.626782811,DB0903710038695_,0.467155193,-0.192288072,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pembrolizumab,DB09037
,618360,DB06186,10075761,16,2193,37,3609,0.319012576,0.711689639,0.368704344,1.314930514,0.487120603,DB0618610075761_,0.719243543,-0.340113363,NA,10075761,Autoimmune colitis,10017947,Gastrointestinal disorders,Gastr,ipilimumab,DB06186
,618480,DB11065,10037087,35,3151,18,2670,0.0964298,1.647485527,0.905690011,3.097590487,0.205401725,DB1106510037087_,1.582787586,0.499250202,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,pancrelipase amylase,DB11065
,618491,DB00490,10020937,63,4007,14,1562,0.055631044,1.754043673,0.968627168,3.400237636,0.135419708,DB0049010020937_,1.999376379,0.561923793,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,buspirone,DB00490
,619161,DB00316,10012335,25,65449,38,36915,0.00010741,0.371072991,0.214625651,0.631060349,0.000848081,DB0031610012335_,7.072534181,-0.991356494,NA,10012335,Dependence,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,619230,DB00019,10069868,987,18025,463,9066,0.230163603,1.072205338,0.956329917,1.203429563,0.386140118,DB0001910069868_,0.951554975,0.069717591,NA,10069868,Device issue,10077536,Product issues,Prod,pegfilgrastim,DB00019
,619232,DB00019,10072694,590,18422,310,9219,0.495171848,0.952441489,0.826738987,1.098912695,0.657505187,DB0001910072694_,0.419302626,-0.048726603,NA,10072694,Application site haemorrhage,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,619485,DB00264,10062189,34,29573,16,24876,0.064020928,1.787468827,0.959798531,3.468672745,0.150679629,DB0026410062189_,1.892599361,0.580800556,NA,10062189,Vitamin D decreased,10022891,Investigations,Inv,metoprolol,DB00264
,619739,DB09035,10008531,43,4683,88,6602,0.049483234,0.6888921,0.465924088,1.00507473,0.124038414,DB0903510008531_,2.087163973,-0.372670624,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,nivolumab,DB09035
,620022,DB09292,10012378,40,4489,43,8219,0.0206439,1.703185092,1.077263706,2.687048636,0.063361436,DB0929210012378_,2.758899868,0.532500081,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,sacubitril,DB09292
,620031,DB09292,10016256,313,4216,527,7735,0.247439474,1.089656782,0.93962387,1.262123857,0.406661867,DB0929210016256_,0.899773233,0.085862768,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,620039,DB09292,10028334,34,4495,47,8215,0.243609364,1.322015704,0.823258992,2.103082828,0.40198636,DB0929210028334_,0.911337122,0.27915762,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,sacubitril,DB09292
,620043,DB09292,10028411,25,4504,51,8211,0.71876165,0.893646204,0.529830618,1.471492119,0.833911611,DB0929210028411_,0.181627864,-0.112445328,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sacubitril,DB09292
,620045,DB09292,10033425,62,4467,94,8168,0.273552618,1.206011849,0.858839508,1.683401087,0.436558123,DB0929210033425_,0.828833756,0.187318923,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,sacubitril,DB09292
,620050,DB09292,10044565,23,4506,36,8226,0.586365291,1.166310122,0.658971917,2.025638899,0.733602022,DB0929210044565_,0.309788601,0.153845023,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,620622,DB00410,10069339,22,1583,40,969,3.25605404520886e-05,0.336815747,0.189423904,0.584544174,0.000305063,DB0041010069339_,8.09499276,-1.088219241,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,mupirocin,DB00410
,620633,DB00531,10011793,23,7229,30,6486,0.214529018,0.687892269,0.381164863,1.226200961,0.366936406,DB0053110011793_,1.002566726,-0.374123038,NA,10011793,Cystitis haemorrhagic,10038359,Renal and urinary disorders,Renal,cyclophosphamide,DB00531
,620819,DB13867,10070608,63,4487,55,2499,0.019827648,0.637965783,0.435720417,0.936571967,0.061347836,DB1386710070608_,2.791195385,-0.449470628,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,fluticasone,DB13867
,620894,DB09107,10013968,225,990,167,836,0.263551854,1.137657908,0.9076036,1.427922205,0.425400674,DB0910710013968_,0.854723791,0.128971683,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methoxy polyethylene glycol-epoetin beta,DB09107
,620896,DB09107,10015150,25,1190,32,971,0.105853486,0.637612964,0.359599162,1.118876076,0.219949318,DB0910710015150_,1.514358133,-0.450023819,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,methoxy polyethylene glycol-epoetin beta,DB09107
,620898,DB09107,10020642,32,1183,30,973,0.607986439,0.877370842,0.51229575,1.506331766,0.750824476,DB0910710020642_,0.286583375,-0.130825523,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,methoxy polyethylene glycol-epoetin beta,DB09107
,620900,DB09107,10028813,195,1020,111,892,0.00081637,1.536000065,1.189049903,1.991326843,0.004656746,DB0910710028813_,5.369438391,0.429181677,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,methoxy polyethylene glycol-epoetin beta,DB09107
,620902,DB09107,10047700,154,1061,84,919,0.001171622,1.587635915,1.190742544,2.128123601,0.006278509,DB0910710047700_,5.070622747,0.462246064,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,methoxy polyethylene glycol-epoetin beta,DB09107
,621560,DB09107,10013573,32,1183,39,964,0.114672199,0.668748323,0.402248862,1.104693133,0.233142109,DB0910710013573_,1.456107101,-0.402347488,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,methoxy polyethylene glycol-epoetin beta,DB09107
,621562,DB09107,10045555,43,1172,56,947,0.022868981,0.620588595,0.403166454,0.949578611,0.068584764,DB0910710045555_,2.67968487,-0.477086904,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,methoxy polyethylene glycol-epoetin beta,DB09107
,621646,DB01224,10046735,33,8075,18,5899,0.394305682,1.33927005,0.731665155,2.529037646,0.564229128,DB0122410046735_,0.572294855,0.292124727,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,quetiapine,DB01224
,621793,DB00668,10023232,43,10048,11,4292,0.13805864,1.66971387,0.845708082,3.593904688,0.267024508,DB0066810023232_,1.320414833,0.512652276,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,epinephrine,DB00668
,622149,DB09027,10046571,38,5141,15,7137,1.68001084885769e-05,3.516545578,1.887384378,6.890255748,0.000171292,DB0902710046571_,8.672140684,1.257479138,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ledipasvir,DB09027
,622704,DB08895,10042868,379,27735,82,6564,0.511865027,1.09385439,0.858112955,1.408532724,0.672160972,DB0889510042868_,0.397257426,0.089707596,NA,10042868,Synovitis,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,622813,DB00874,10054112,30,3305,21,1955,0.562836041,0.845073919,0.466495706,1.557676074,0.715021162,DB0087410054112_,0.33544314,-0.168331178,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,guaifenesin,DB00874
,622815,DB01069,10054112,58,6642,25,2370,0.452639802,0.827812259,0.508365476,1.384529962,0.620266256,DB0106910054112_,0.477606448,-0.188968891,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,promethazine,DB01069
,622887,DB00987,10029331,20,2084,31,2897,0.776247814,0.89684175,0.483052883,1.629607216,0.877982174,DB0098710029331_,0.130128988,-0.108875854,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,cytarabine,DB00987
,623380,DB05676,10024855,37,47092,22,25307,0.684776475,0.903804419,0.519205684,1.608772403,0.809622937,DB0567610024855_,0.21118665,-0.101142293,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,623383,DB05676,10049848,36,47093,21,25308,0.781897113,0.921267812,0.523380232,1.661257301,0.881222599,DB0567610049848_,0.126445019,-0.082004501,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,apremilast,DB05676
,623765,DB06637,10051313,46,6116,25,1994,0.051625279,0.59993761,0.359921317,1.021794148,0.12809463,DB0663710051313_,2.054985994,-0.510929613,NA,10051313,B-lymphocyte count decreased,10022891,Investigations,Inv,dalfampridine,DB06637
,623936,DB05676,10009033,49,47080,29,25300,0.721806309,0.907995842,0.562160998,1.491051028,0.836058645,DB0567610009033_,0.179056519,-0.09651548,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apremilast,DB05676
,624146,DB09073,10035528,422,19838,19,771,0.525264305,0.863215025,0.542108438,1.456377097,0.683356683,DB0907310035528_,0.380738326,-0.147091459,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,palbociclib,DB09073
,624148,DB09073,10038153,373,19887,9,781,0.173249882,1.627591778,0.843728152,3.601252161,0.315179648,DB0907310038153_,1.154612493,0.487101486,NA,10038153,Red blood cell count decreased,10022891,Investigations,Inv,palbociclib,DB09073
,624183,DB09073,10048959,273,19987,8,782,0.527043049,1.335145986,0.66473996,3.135219531,0.684706613,DB0907310048959_,0.378764835,0.289040638,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,palbociclib,DB09073
,624264,DB09029,10027599,70,11274,17,7253,0.000147303,2.648909987,1.540897335,4.805776692,0.001108782,DB0902910027599_,6.804492804,0.97414823,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,secukinumab,DB09029
,624450,DB09107,10016825,117,1098,91,912,0.661493151,1.067907694,0.793292621,1.440989248,0.793526116,DB0910710016825_,0.231268828,0.065701308,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,methoxy polyethylene glycol-epoetin beta,DB09107
,624451,DB09107,10021097,43,1172,47,956,0.194582434,0.746383984,0.477362166,1.164442322,0.342491665,DB0910710021097_,1.071507959,-0.292515088,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,methoxy polyethylene glycol-epoetin beta,DB09107
,624517,DB09045,10000059,34,2315,28,1696,0.698192592,0.889629154,0.521354786,1.529386148,0.818481504,DB0904510000059_,0.200304479,-0.116950584,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,dulaglutide,DB09045
,624554,DB09073,10076309,279,19981,175,615,1.4876524560117e-132,0.049094394,0.039780248,0.060667441,4.88786810078344e-129,DB0907310076309_,295.4467208,-3.014010419,male,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,palbociclib,DB09073
,624564,DB09073,10042128,806,19454,10,780,1.87443744450339e-05,3.231511601,1.738447471,6.792932537,0.000188736,DB0907310042128_,8.57516022,1.172950016,female,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,palbociclib,DB09073
,624566,DB09073,10060800,485,19775,15,775,0.473370543,1.267167257,0.75582821,2.293029714,0.639308656,DB0907310060800_,0.447367912,0.236783903,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,palbociclib,DB09073
,624638,DB01065,10047942,56,4275,31,3020,0.32441837,1.276094771,0.806489269,2.053054913,0.492881154,DB0106510047942_,0.7074872,0.243804454,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,melatonin,DB01065
,624686,DB00635,10067757,19,33034,38,23756,0.000219357,0.359574499,0.195725337,0.639556415,0.001557275,DB0063510067757_,6.464817586,-1.022833895,male,10067757,Focal segmental glomerulosclerosis,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,624947,DB00480,10065154,53,67375,94,67568,0.000902749,0.565450715,0.395920906,0.800257778,0.005064403,DB0048010065154_,5.285519028,-0.570132141,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,lenalidomide,DB00480
,625108,DB09073,10017577,168,20092,7,783,0.840208585,0.935328119,0.441971641,2.37002577,0.918252158,DB0907310017577_,0.085283244,-0.066857881,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,palbociclib,DB09073
,625118,DB09073,10025482,568,19692,9,781,0.002578453,2.502961439,1.302279747,5.523026326,0.011952144,DB0907310025482_,4.426844629,0.917474606,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,palbociclib,DB09073
,625165,DB09073,10028372,120,20140,6,784,0.478988692,0.778561737,0.34585766,2.170536637,0.644165657,DB0907310028372_,0.439799354,-0.250306988,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,palbociclib,DB09073
,625188,DB09073,10033371,665,19595,11,779,0.00185741,2.403303484,1.32687344,4.858328392,0.00915642,DB0907310033371_,4.693300052,0.876844243,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,palbociclib,DB09073
,625330,DB00669,10069217,59,6318,16,1081,0.102359409,0.630972828,0.356717856,1.179331109,0.214537681,DB0066910069217_,1.539269887,-0.460492479,NA,10069217,Needle issue,10077536,Product issues,Prod,sumatriptan,DB00669
,625528,DB09029,10033371,497,10847,269,7001,0.023235253,1.192452743,1.022772995,1.392646281,0.069427511,DB0902910033371_,2.667472073,0.176012315,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,625530,DB09029,10050584,80,11264,29,7241,0.00764255,1.773310403,1.145123143,2.816723572,0.028722394,DB0902910050584_,3.550078182,0.572848084,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,625538,DB00169,10012239,28,38663,41,18134,3.2889315251075e-06,0.320318348,0.190702086,0.530839305,4.10005051636e-05,DB0016910012239_,10.10192617,-1.138439942,male,10012239,Delusion,10037175,Psychiatric disorders,Psych,cholecalciferol,DB00169
,625583,DB00443,10000059,49,2097,24,1166,0.711188935,1.135210874,0.679204886,1.9451243,0.827814237,DB0044310000059_,0.188966502,0.126818426,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,betamethasone,DB00443
,625639,DB08895,10065154,289,27825,71,6575,0.787514954,0.961830884,0.738443781,1.267073193,0.884872849,DB0889510065154_,0.122311318,-0.03891664,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,tofacitinib,DB08895
,625830,DB00999,10073317,37,21393,19,12220,0.781804169,1.112377086,0.623189258,2.048724187,0.881222599,DB0099910073317_,0.126445019,0.106499245,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,626038,DB01234,10042254,12,31613,80,32808,4.49427061820309e-13,0.155675745,0.077209241,0.287298044,2.10573802494596e-11,DB0123410042254_,24.58377001,-1.859979996,male,10042254,Strongyloidiasis,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,626069,DB00422,10067482,41,3394,77,2872,3.40421892819001e-05,0.450625991,0.299681176,0.669006381,0.00031708,DB0042210067482_,8.056357361,-0.797117572,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,626200,DB09034,10013573,42,1134,21,657,0.690001364,1.158671676,0.664195024,2.078566095,0.813015717,DB0903410013573_,0.207004838,0.147274242,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,suvorexant,DB09034
,626369,DB09073,10018884,247,20013,12,778,0.410461344,0.800182111,0.447310672,1.576767549,0.579849861,DB0907310018884_,0.544986069,-0.222915938,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,palbociclib,DB09073
,626745,DB09035,10028813,179,4547,179,6511,0.000870376,1.431859033,1.153213517,1.777859744,0.004913624,DB0903510028813_,5.315743424,0.358973623,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,nivolumab,DB09035
,626980,DB08904,10000059,74,11536,19,3540,0.541151234,1.195143449,0.713080414,2.09890297,0.696538393,DB0890410000059_,0.361632365,0.178266219,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,certolizumab pegol,DB08904
,627036,DB09073,10024384,319,19941,9,781,0.461480014,1.388191448,0.718348145,3.075364854,0.628741852,DB0907310024384_,0.464034517,0.328001783,NA,10024384,Leukopenia,10005329,Blood and lymphatic system disorders,Blood,palbociclib,DB09073
,627037,DB09073,10066274,91,20169,6,784,0.181606988,0.589573105,0.259498029,1.653629194,0.325927877,DB0907310066274_,1.12107916,-0.528356554,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,palbociclib,DB09073
,627099,DB00341,10043417,42,11363,16,5052,0.67049065,1.167057819,0.641835522,2.225837333,0.800083838,DB0034110043417_,0.22303876,0.154485897,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,cetirizine,DB00341
,627289,DB00836,10013754,34,5501,37,4038,0.11659537,0.674571085,0.409925847,1.106861047,0.236028288,DB0083610013754_,1.443803618,-0.393678219,NA,10013754,Drug withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,loperamide,DB00836
,627374,DB08904,10022004,82,11528,25,3534,1,1.005510103,0.63467928,1.645422238,1,DB0890410022004_,0,0.005494978,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,627582,DB05676,10013082,186,46943,118,25211,0.165679619,0.846555909,0.668227513,1.076008382,0.305042694,DB0567610013082_,1.187303532,-0.166579033,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,627590,DB00175,10012671,33,8098,20,6086,0.489077352,1.240027856,0.690001247,2.282822709,0.652475482,DB0017510012671_,0.426981715,0.215133844,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,pravastatin,DB00175
,627943,DB09183,10047700,40,435,45,682,0.166941552,1.393186434,0.871000419,2.221963631,0.306739274,DB0918310047700_,1.181757161,0.331593522,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,dasabuvir,DB09183
,628014,DB00688,10048983,29,6461,30,5348,0.432406312,0.800163207,0.462768407,1.381622334,0.600812189,DB0068810048983_,0.50947289,-0.222939564,NA,10048983,Cytomegalovirus colitis,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,628028,DB09029,10064355,532,10812,413,6857,0.002897157,0.816956038,0.714443693,0.93464047,0.013135276,DB0902910064355_,4.332453849,-0.202169994,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,628099,DB09029,10000087,82,11262,49,7221,0.720219421,1.073005848,0.743207019,1.563484334,0.834864391,DB0902910000087_,0.180485974,0.070463914,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,628103,DB09029,10012735,480,10864,265,7005,0.046370989,1.167878028,1,1.366260707,0.118221285,DB0902910012735_,2.135197113,0.15518845,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,628116,DB09029,10047700,102,11242,55,7215,0.324669159,1.190182162,0.848072315,1.685902307,0.49316074,DB0902910047700_,0.706920113,0.174106373,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,628379,DB09029,10063829,301,11043,282,6988,3.72993156661819e-06,0.675469574,0.570616135,0.799692125,4.56642995941122e-05,DB0902910063829_,9.994193756,-0.392347165,NA,10063829,Device malfunction,10077536,Product issues,Prod,secukinumab,DB09029
,628380,DB09029,10068319,153,11191,41,7229,1.09355737066376e-07,2.410442717,1.695494996,3.495855558,1.96675713225433e-06,DB0902910068319_,13.1391245,0.879810431,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,secukinumab,DB09029
,628381,DB09029,10022086,226,11118,104,7166,0.004399848,1.400610707,1.103272844,1.787669349,0.018447917,DB0902910022086_,3.99280379,0.336908361,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,628453,DB08907,10040943,13,4240,51,3859,2.13656036914871e-07,0.232060281,0.115589154,0.433685474,3.59766107002395e-06,DB0890710040943_,12.53522663,-1.460758108,male,10040943,Skin ulcer,10040785,Skin and subcutaneous tissue disorders,Skin,canagliflozin,DB08907
,628534,DB00215,10037162,43,11060,9,5267,0.024688799,2.27518,1.092907475,5.311573632,0.072821084,DB0021510037162_,2.61974975,0.82205917,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,citalopram,DB00215
,628939,DB01012,10067973,123,10509,87,8598,0.328952338,1.156690938,0.87047895,1.542589998,0.497555081,DB0101210067973_,0.698049013,0.145563289,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,cinacalcet,DB01012
,629255,DB00921,10047513,31,5814,27,4876,0.895613384,0.962900372,0.555260359,1.679381605,0.95615204,DB0092110047513_,0.044838341,-0.037805329,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,buprenorphine,DB00921
,629455,DB09035,10028411,30,4696,50,6640,0.496846933,0.848409804,0.520003786,1.36281457,0.658994405,DB0903510028411_,0.417040234,-0.1643915,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,nivolumab,DB09035
,629660,DB00188,10067482,37,7849,47,8781,0.585474327,0.880718976,0.555947282,1.385955728,0.732993222,DB0018810067482_,0.310618825,-0.127016687,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,bortezomib,DB00188
,629910,DB00190,10045555,28,3269,42,4632,0.903140313,0.944629936,0.562620383,1.563985923,0.957326661,DB0019010045555_,0.043610607,-0.05696203,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,630694,DB00684,10054112,257,2535,231,2117,0.445105762,0.929122536,0.767448451,1.125304247,0.613107231,DB0068410054112_,0.48921543,-0.073514648,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,tobramycin,DB00684
,630736,DB09035,10053762,163,4563,197,6493,0.142019219,1.177357028,0.94739608,1.461582681,0.272629189,DB0903510053762_,1.299642689,0.16327212,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,nivolumab,DB09035
,630742,DB00761,10022061,45,15262,8,8617,0.001360603,3.175772506,1.480692368,7.805656411,0.007097331,DB0076110022061_,4.948036475,1.155550912,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,630749,DB09029,10013709,1480,9864,998,6272,0.184623604,0.942943596,0.864272575,1.029059294,0.329720848,DB0902910013709_,1.109508898,-0.058748812,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,630933,DB00471,10024264,49,14140,18,5447,1,1.048631563,0.599453052,1.914460654,1,DB0047110024264_,0,0.047486041,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,montelukast,DB00471
,631221,DB00921,10076309,259,5586,192,4711,0.192361672,1.137637266,0.936371064,1.384059062,0.339617582,DB0092110076309_,1.079935055,0.128953538,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,buprenorphine,DB00921
,631282,DB01224,10037153,45,8063,14,5903,0.00354496,2.35305538,1.266991235,4.646043583,0.015477001,DB0122410037153_,4.168400183,0.855714645,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,quetiapine,DB01224
,631378,DB06285,10048959,114,8736,11,1095,0.4755916,1.298975752,0.696387768,2.684160528,0.64116317,DB0628510048959_,0.444471299,0.261576071,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,teriparatide,DB06285
,631483,DB08932,10006002,81,19362,23,6574,0.499088141,1.19572696,0.744052329,1.993208491,0.66097939,DB0893210006002_,0.41403262,0.178754335,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,macitentan,DB08932
,631612,DB08932,10012374,50,19393,11,6586,0.237833111,1.543597016,0.792619711,3.290300486,0.395310695,DB0893210012374_,0.928083253,0.434115417,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,macitentan,DB08932
,631630,DB08932,10048865,125,19318,39,6558,0.718778827,1.088060484,0.753130651,1.603350605,0.833911611,DB0893210048865_,0.181627864,0.084396738,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,macitentan,DB08932
,631637,DB00820,10070617,53,11862,6,5810,7.4686925379993e-05,4.326851181,1.859764107,12.32401433,0.000620463,DB0082010070617_,7.385044125,1.464840068,female,10070617,Device infusion issue,10077536,Product issues,Prod,tadalafil,DB00820
,631639,DB08932,10070617,54,19389,13,6584,0.324776967,1.410493454,0.75907417,2.819446073,0.493212154,DB0893210070617_,0.706815865,0.343939611,NA,10070617,Device infusion issue,10077536,Product issues,Prod,macitentan,DB08932
,631645,DB08932,10065464,56,19387,12,6585,0.163512916,1.585002007,0.839164885,3.251265015,0.302118445,DB0893210065464_,1.196936137,0.460585674,NA,10065464,Infusion site haemorrhage,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,632083,DB00019,10020751,45,18967,16,9513,0.277461064,1.410608334,0.781634453,2.675251746,0.441054946,DB0001910020751_,0.818585816,0.344021054,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,pegfilgrastim,DB00019
,632870,DB00829,10057668,34,8018,16,4438,0.658863189,1.176160344,0.63093168,2.284696372,0.791655557,DB0082910057668_,0.233628884,0.162255187,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,diazepam,DB00829
,634850,DB00381,10058920,47,29313,19,22868,0.017662168,1.929758458,1.110689653,3.482944619,0.056048545,DB0038110058920_,2.881537089,0.657394844,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,635112,DB01006,10020937,93,5854,6,171,0.066138664,0.452845378,0.196457534,1.283328557,0.154412647,DB0100610020937_,1.868126737,-0.792204541,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,letrozole,DB01006
,635137,DB00997,10041101,76,5255,27,3487,0.004470699,1.867667607,1.186945659,3.021101703,0.018677948,DB0099710041101_,3.980411677,0.624690383,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,doxorubicin,DB00997
,635326,DB00211,10053762,36,1400,28,1603,0.130719515,1.471943324,0.868430001,2.518077026,0.256788794,DB0021110053762_,1.359501344,0.386583517,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,midodrine,DB00211
,636213,DB01183,10013968,34,525,26,522,0.354376035,1.299908676,0.745448399,2.290534737,0.524214873,DB0118310013968_,0.645853615,0.262294013,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,naloxone,DB01183
,636784,DB06282,10053762,55,1485,14,519,0.329364239,1.372786627,0.745433831,2.696773311,0.498006156,DB0628210053762_,0.697142841,0.316842708,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,levocetirizine,DB06282
,637415,DB01060,10061623,32,8555,27,5054,0.17864634,0.700208901,0.405840455,1.216349652,0.322187317,DB0106010061623_,1.132622172,-0.356376559,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,amoxicillin,DB01060
,637739,DB01390,10053762,53,1356,45,1472,0.258271288,1.27841926,0.83679263,1.960349806,0.419234287,DB0139010053762_,0.869325357,0.245624361,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium bicarbonate,DB01390
,639400,DB01234,10028997,36,31589,28,32860,0.262119244,1.337434315,0.793378328,2.275997266,0.423831467,DB0123410028997_,0.858419387,0.290753088,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,dexamethasone,DB01234
,639477,DB01590,10047942,54,4684,16,2851,0.009203522,2.054076355,1.155512574,3.852818149,0.033316978,DB0159010047942_,3.401688165,0.719826285,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,everolimus,DB01590
,639543,DB00541,10042772,38,3096,25,4272,0.00448453,2.097177219,1.230487633,3.633266786,0.01872441,DB0054110042772_,3.977927255,0.740592259,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,vincristine,DB00541
,639785,DB00190,10008479,34,3263,32,4642,0.102932827,1.511417552,0.902908259,2.535726204,0.215396017,DB0019010008479_,1.535277005,0.413047987,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,640507,DB08893,10012378,45,2040,11,1047,0.031256665,2.099169435,1.063413766,4.519778105,0.087481386,DB0889310012378_,2.436329239,0.741541759,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,mirabegron,DB08893
,640573,DB08893,10027175,35,2050,16,1042,0.767670054,1.111848152,0.596131332,2.162012854,0.872420225,DB0889310027175_,0.136484062,0.106023632,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,mirabegron,DB08893
,640862,DB00697,10020751,58,6038,10,1796,0.145352645,1.725054412,0.871889711,3.793479401,0.277558611,DB0069710020751_,1.281723157,0.545258593,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,tizanidine,DB00697
,641981,DB00684,10036790,30,2762,44,2304,0.018520193,0.568828046,0.344083498,0.928772211,0.05815083,DB0068410036790_,2.844715119,-0.564177095,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tobramycin,DB00684
,642001,DB08932,10020765,55,19388,20,6577,0.790738207,0.932879917,0.549760277,1.644602555,0.88663055,DB0893210020765_,0.1203269,-0.069478792,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,642029,DB00820,10052271,57,11858,11,5805,0.002712006,2.536609426,1.315361574,5.369272938,0.012449368,DB0082010052271_,4.386085407,0.930828318,NA,10052271,Catheter site rash,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,642031,DB08932,10052271,79,19364,22,6575,0.49151945,1.219269222,0.751501212,2.056272591,0.654620427,DB0893210052271_,0.423699712,0.198251681,NA,10052271,Catheter site rash,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,642995,DB08931,10048634,47,6530,15,2431,0.669180856,1.166458945,0.639452025,2.250356295,0.799162431,DB0893110048634_,0.224191061,0.153972617,NA,10048634,Infusion site erythema,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,643007,DB08931,10064684,59,6518,14,2432,0.145879978,1.572433969,0.865349769,3.055528088,0.278272068,DB0893110064684_,1.279155982,0.452624718,NA,10064684,Device dislocation,10077536,Product issues,Prod,riociguat,DB08931
,644233,DB00646,10023232,37,3416,20,1980,0.890444988,1.07230063,0.604509455,1.955658453,0.954638381,DB0064610023232_,0.046422669,0.069806462,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,nystatin,DB00646
,644240,DB00656,10028391,60,11953,18,6601,0.023722131,1.840765548,1.071040701,3.315833562,0.070591669,DB0065610028391_,2.65084314,0.610181544,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,644973,DB01065,10022000,59,4272,28,3023,0.099885846,1.491001006,0.933196247,2.434766933,0.210604378,DB0106510022000_,1.557773893,0.39944771,NA,10022000,Influenza,10021881,Infections and infestations,Infec,melatonin,DB01065
,645450,DB00451,10040560,33,47238,28,15391,0.000283244,0.384006812,0.22493798,0.659839408,0.001926389,DB0045110040560_,6.252107815,-0.957094987,NA,10040560,Shock,10047065,Vascular disorders,Vasc,levothyroxine,DB00451
,645577,DB00213,10001480,34,18861,29,13392,0.522680261,0.832465801,0.49196387,1.417191496,0.681159705,DB0021310001480_,0.383958485,-0.183363138,NA,10001480,Ageusia,10029205,Nervous system disorders,Nerv,pantoprazole,DB00213
,646573,DB01043,10033371,42,1359,16,1394,0.000495174,2.691758516,1.473488415,5.153809272,0.003067199,DB0104310033371_,5.786990655,0.990194703,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,memantine,DB01043
,646588,DB00476,10076308,128,17129,36,6141,0.213740156,1.274692394,0.873527902,1.902340737,0.365908558,DB0047610076308_,1.005371817,0.24270489,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,646843,DB01026,10047895,25,1085,31,1037,0.3469066,0.770869244,0.433169854,1.359306799,0.516332955,DB0102610047895_,0.66100346,-0.260236512,NA,10047895,Weight decreased,10022891,Investigations,Inv,ketoconazole,DB01026
,646934,DB00829,10017944,35,8017,15,4439,0.4613738,1.29195939,0.686639727,2.549244612,0.628664915,DB0082910017944_,0.46415689,0.256159973,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,diazepam,DB00829
,647212,DB09078,10003239,30,763,42,1014,0.903528143,0.949277916,0.568003998,1.569388639,0.957409002,DB0907810003239_,0.043524599,-0.052053672,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,lenvatinib,DB09078
,647217,DB09078,10016256,124,669,232,824,0.00067049,0.658466549,0.512938686,0.842575688,0.003954193,DB0907810016256_,5.532978644,-0.417841557,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lenvatinib,DB09078
,647218,DB09078,10019211,48,745,56,1000,0.540820025,1.150436518,0.75640365,1.744164565,0.696306941,DB0907810019211_,0.361964709,0.140141452,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,lenvatinib,DB09078
,647219,DB09078,10028813,110,683,113,943,0.043241832,1.34378142,1.004865378,1.79669275,0.112142287,DB0907810028813_,2.187986792,0.295487595,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,lenvatinib,DB09078
,647223,DB09078,10047700,76,717,71,985,0.029621466,1.470183882,1.034091329,2.092288574,0.083869255,DB0907810047700_,2.478496182,0.385387483,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lenvatinib,DB09078
,647260,DB00820,10061225,43,11872,8,5808,0.010255789,2.629428594,1.220989593,6.479386806,0.036293965,DB0082010061225_,3.316103817,0.966766558,NA,10061225,Limb injury,10022117,"Injury, poisoning and procedural complications",Inj&P,tadalafil,DB00820
,647383,DB00207,10054236,32,9048,18,5437,0.884464145,1.068280287,0.581186114,2.023433414,0.951918915,DB0020710054236_,0.049275421,0.066050147,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,azithromycin,DB00207
,647666,DB00374,10052271,45,17671,18,5706,0.462814329,0.807254316,0.457640355,1.483003068,0.630044157,DB0037410052271_,0.461965371,-0.214116523,NA,10052271,Catheter site rash,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,648082,DB06605,10013700,96,13977,57,12976,0.007351069,1.563559567,1.114063318,2.211732834,0.027837899,DB0660510013700_,3.581356902,0.446964995,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,apixaban,DB06605
,648249,DB00421,10064684,46,8857,7,5245,0.000161792,3.891222254,1.743241379,10.22323321,0.00120303,DB0042110064684_,6.722911665,1.358723312,female,10064684,Device dislocation,10077536,Product issues,Prod,spironolactone,DB00421
,648323,DB00182,10054112,37,5157,18,2834,0.777660051,1.129618988,0.625675931,2.111844709,0.878774377,DB0018210054112_,0.129227096,0.121880397,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,amphetamine,DB00182
,648765,DB05676,10014551,48,47081,19,25310,0.305417354,1.35810182,0.783347452,2.447101109,0.472208349,DB0567610014551_,0.750334974,0.306088004,NA,10014551,Emotional disorder,10037175,Psychiatric disorders,Psych,apremilast,DB05676
,648911,DB06403,10043882,54,21417,9,6652,0.10111349,1.863458282,0.911876611,4.295563154,0.212493951,DB0640310043882_,1.548841755,0.622434053,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,ambrisentan,DB06403
,649203,DB08907,10060933,47,4206,42,3868,0.915413605,1.029120859,0.662582428,1.603078804,0.962143444,DB0890710060933_,0.03859173,0.028704903,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,canagliflozin,DB08907
,649763,DB09078,10033371,27,766,49,1007,0.19498854,0.724507204,0.431160274,1.194541526,0.342976797,DB0907810033371_,1.070092481,-0.322263573,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,lenvatinib,DB09078
,649920,DB08931,10008531,83,6494,36,2410,0.467336705,0.855653417,0.570317092,1.306658187,0.633862859,DB0893110008531_,0.455922658,-0.155889871,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,649937,DB06605,10033433,160,13913,67,12966,1.46002517242055e-08,2.225341542,1.661367066,3.009206512,3.16118300305389e-07,DB0660510033433_,14.96714933,0.799910406,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,apixaban,DB06605
,650310,DB00734,10043118,29,4021,43,4859,0.408342992,0.814990435,0.489754667,1.338516492,0.577742251,DB0073410043118_,0.548627442,-0.204578902,NA,10043118,Tardive dyskinesia,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,650541,DB00688,10043645,44,6446,49,5329,0.173852815,0.742380194,0.481824622,1.140733429,0.315948508,DB0068810043645_,1.152176026,-0.297893776,NA,10043645,Thrombotic microangiopathy,10005329,Blood and lymphatic system disorders,Blood,mycophenolate mofetil,DB00688
,650555,DB01068,10001052,34,13729,22,6818,0.324010857,0.76752979,0.435655225,1.378682894,0.492432806,DB0106810001052_,0.708397262,-0.264577986,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,clonazepam,DB01068
,651408,DB00563,10019851,68,46578,31,15317,0.130900896,0.721344447,0.464994189,1.142025326,0.257049049,DB0056310019851_,1.35848836,-0.32663852,NA,10019851,Hepatotoxicity,10019805,Hepatobiliary disorders,Hepat,methotrexate,DB00563
,651446,DB00959,10043521,76,8002,14,4988,3.26661095118271e-06,3.383600101,1.895545033,6.487846149,4.07802749236939e-05,DB0095910043521_,10.10731205,1.218940261,female,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methylprednisolone,DB00959
,652384,DB00843,10054112,30,2164,26,2147,0.687156836,1.144745565,0.651944617,2.022483261,0.811324139,DB0084310054112_,0.209087626,0.135182399,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,donepezil,DB00843
,652511,DB00704,10022086,608,3748,826,4368,0.008153302,0.857855063,0.764428328,0.962350055,0.030259024,DB0070410022086_,3.497960824,-0.153320118,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,652513,DB00704,10022998,53,4303,82,5112,0.139906264,0.767881061,0.531728931,1.100761822,0.269715512,DB0070410022998_,1.310387534,-0.264120426,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,652515,DB00704,10027940,31,4325,34,5160,0.802972017,1.087783199,0.64539016,1.827380985,0.893342905,DB0070410027940_,0.11278478,0.084141863,NA,10027940,Mood altered,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,652521,DB00704,10033775,30,4326,34,5160,0.89999975,1.052483318,0.621035709,1.77532495,0.956571579,DB0070410033775_,0.044399659,0.051152437,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,naltrexone,DB00704
,652592,DB00368,10069339,51,609,102,696,0.001928827,0.571644364,0.393067199,0.823092449,0.009454401,DB0036810069339_,4.661274924,-0.559238223,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,norepinephrine,DB00368
,652969,DB00287,10020751,56,1345,18,799,0.026773194,1.847693886,1.061083908,3.364566315,0.07749941,DB0028710020751_,2.557484951,0.613938313,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,travoprost,DB00287
,653375,DB00531,10012821,28,7224,36,6480,0.168080182,0.697697785,0.409584086,1.177279012,0.308260367,DB0053110012821_,1.176810507,-0.359969243,NA,10012821,Diffuse large B-cell lymphoma recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyclophosphamide,DB00531
,653613,DB09146,10016825,52,736,29,398,0.904497568,0.969640664,0.593409005,1.611278813,0.957573483,DB0914610016825_,0.043352816,-0.030829726,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,iron sucrose,DB09146
,653661,DB09073,10000087,245,20015,9,781,1,1.062228473,0.547614447,2.359828945,1,DB0907310000087_,0,0.060369035,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,palbociclib,DB09073
,653662,DB09073,10008479,157,20103,6,784,1,1.02047693,0.45644287,2.831797423,1,DB0907310008479_,0,0.020270096,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,palbociclib,DB09073
,654612,DB08895,10067482,98,28016,29,6617,0.3081727,0.798153127,0.522256914,1.25437685,0.475413501,DB0889510067482_,0.743570326,-0.225454812,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,654622,DB06228,10076308,41,15871,25,16051,0.048597802,1.658563531,0.98427135,2.847429963,0.122437767,DB0622810076308_,2.100152404,0.505951885,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,654681,DB09073,10017412,486,19774,14,776,0.338772117,1.362303381,0.799125739,2.522562484,0.50786109,DB0907310017412_,0.677547314,0.309176929,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,palbociclib,DB09073
,654723,DB00512,10029350,37,4700,52,5046,0.241217391,0.763942232,0.486241575,1.189513263,0.399358334,DB0051210029350_,0.917896185,-0.269263105,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,vancomycin,DB00512
,655135,DB09029,10000081,84,11260,61,7209,0.494356831,0.881638148,0.625598217,1.248612552,0.656868329,DB0902910000081_,0.420271692,-0.12597357,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,655136,DB09029,10008531,48,11296,28,7242,0.72528388,1.099060726,0.675017679,1.821100527,0.838945789,DB0902910008531_,0.175609188,0.09445593,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,655137,DB09029,10022004,51,11293,39,7231,0.448564853,0.837339935,0.540469172,1.306295091,0.616256483,DB0902910022004_,0.484092034,-0.177525156,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,656368,DB06285,10020937,52,8798,7,1099,0.834648157,0.927921904,0.418472756,2.427593431,0.914208847,DB0628510020937_,0.089696235,-0.074807705,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,teriparatide,DB06285
,656373,DB06285,10042609,71,8779,7,1099,0.71682366,1.26968372,0.583234684,3.28053223,0.832561969,DB0628510042609_,0.183247623,0.23876783,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,teriparatide,DB06285
,656481,DB00073,10051398,36,7370,54,6353,0.010678127,0.574701825,0.365616747,0.893743735,0.037515816,DB0007310051398_,3.282992675,-0.553903938,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,rituximab,DB00073
,656701,DB08906,10012735,118,2075,47,1111,0.093917733,1.344136682,0.942747876,1.942846385,0.201619248,DB0890610012735_,1.601374272,0.295751935,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,fluticasone furoate,DB08906
,656772,DB08912,10012735,58,1272,42,1492,0.019034086,1.619502647,1.061937359,2.487982035,0.059451125,DB0891210012735_,2.822600738,0.482119094,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dabrafenib,DB08912
,657079,DB09073,10029366,378,19882,10,780,0.278823287,1.482940843,0.793165698,3.130546564,0.442671545,DB0907310029366_,0.814927216,0.394027173,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,palbociclib,DB09073
,657087,DB00005,10074425,63,128019,20,42399,1,1.043285157,0.62226738,1.822030969,1,DB0000510074425_,0,0.042374539,NA,10074425,Device defective,10077536,Product issues,Prod,etanercept,DB00005
,657546,DB09029,10018836,30,11314,23,7247,0.573278925,0.835493047,0.46885581,1.507387447,0.723199001,DB0902910018836_,0.324070852,-0.179733254,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,657549,DB09029,10046571,203,11141,34,7236,5.65018604657888e-17,3.877614073,2.683357745,5.759541949,4.32358486853933e-15,DB0902910046571_,33.07469151,1.355220035,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,secukinumab,DB09029
,657733,DB08904,10022107,66,11544,6,3553,0.00121668,3.38546286,1.473527413,9.563360561,0.006471805,DB0890410022107_,5.04030027,1.219490636,female,10022107,Injection site urticaria,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,658528,DB00678,10042209,66,15533,20,10704,0.000875411,2.273996027,1.360431996,3.962818691,0.004937808,DB0067810042209_,5.310833865,0.821538648,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,losartan,DB00678
,659117,DB08931,10025127,57,6520,21,2425,1,1.009531912,0.601073434,1.757111216,1,DB0893110025127_,0,0.00948677,NA,10025127,Lung transplant,10042613,Surgical and medical procedures,Surg,riociguat,DB08931
,659954,DB01222,10063829,83,9191,36,5369,0.15232182,1.346783401,0.89905303,2.053868033,0.287194537,DB0122210063829_,1.247595462,0.297719084,NA,10063829,Device malfunction,10077536,Product issues,Prod,budesonide,DB01222
,659972,DB00864,10007515,28,6841,82,8310,2.86874391160574e-05,0.414820211,0.259653014,0.644892021,0.000272824,DB0086410007515_,8.206682604,-0.87991008,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,tacrolimus,DB00864
,660179,DB00213,10061394,35,18860,16,13405,0.156288155,1.554772606,0.837770329,3.009789904,0.2924284,DB0021310061394_,1.229535428,0.441329301,NA,10061394,Upper limb fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,660328,DB04951,10016173,37,1845,38,3019,0.054535369,1.593035309,0.981321119,2.58421032,0.133525422,DB0495110016173_,2.013463395,0.465641196,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,pirfenidone,DB04951
,661274,DB00924,10064848,71,10091,30,4221,1,0.989961918,0.636517572,1.574274639,1,DB0092410064848_,0,-0.010088803,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,cyclobenzaprine,DB00924
,661568,DB01175,10042609,54,10670,11,4881,0.01069843,2.245570006,1.159578757,4.767706406,0.037568482,DB0117510042609_,3.281589827,0.808959389,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,escitalopram,DB01175
,661575,DB00204,10047302,9,955,43,1000,3.84567641886561e-06,0.219315471,0.0934714,0.459278613,4.69283215737616e-05,DB0020410047302_,9.966889193,-1.517244078,male,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,dofetilide,DB00204
,662239,DB00997,10061309,45,5286,25,3489,0.540993501,1.188027743,0.711625405,2.025698339,0.696388893,DB0099710061309_,0.361847021,0.172294573,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,doxorubicin,DB00997
,662720,DB04951,10017885,29,1853,34,3023,0.194295519,1.391362578,0.814819785,2.361790851,0.342124114,DB0495110017885_,1.0725817,0.330283539,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,pirfenidone,DB04951
,663161,DB00669,10022067,78,6299,11,1086,0.651334298,1.22250057,0.644301131,2.558016213,0.785768405,DB0066910022067_,0.24109318,0.200898408,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,663321,DB01073,10075160,24,1041,34,1616,0.786129123,1.09574028,0.617843747,1.91521698,0.883958076,DB0107310075160_,0.123345643,0.09143019,NA,10075160,Graft versus host disease in gastrointestinal tract,10021428,Immune system disorders,Immun,fludarabine,DB01073
,663645,DB00888,10048941,22,655,30,735,0.571960059,0.823012041,0.447517823,1.491915284,0.722058026,DB0088810048941_,0.325649775,-0.194784448,NA,10048941,Application site vesicles,10018065,General disorders and administration site conditions,Genrl,mechlorethamine,DB00888
,663673,DB00916,10002198,40,5283,15,2416,0.562585111,1.219458604,0.657595105,2.381239425,0.714788749,DB0091610002198_,0.335768235,0.198406993,NA,10002198,Anaphylactic reaction,10021428,Immune system disorders,Immun,metronidazole,DB00916
,663805,DB00619,10047899,38,2861,21,2473,0.115041458,1.563991163,0.892110962,2.813165305,0.23366546,DB0061910047899_,1.453864847,0.447240992,NA,10047899,Weight increased,10022891,Investigations,Inv,imatinib,DB00619
,664118,DB09065,10013573,12,740,39,1898,0.532120685,0.789267936,0.374060687,1.549060521,0.688977156,DB0906510013573_,0.372547164,-0.236649427,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,cobicistat,DB09065
,664193,DB00331,10016970,41,24905,10,20742,0.000186796,3.414479224,1.681572256,7.647622862,0.001362167,DB0033110016970_,6.598678527,1.228024985,female,10016970,Foot fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,665004,DB00656,10043417,32,11981,21,6598,0.566215756,0.839187045,0.468798837,1.532564413,0.717615234,DB0065610043417_,0.33182174,-0.175321659,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,665369,DB09045,10005557,157,2192,130,1594,0.292892632,0.878251717,0.68526169,1.127024635,0.458475532,DB0904510005557_,0.779848354,-0.129822033,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,dulaglutide,DB09045
,665554,DB00451,10061920,48,47223,17,15402,0.773604339,0.920899559,0.519952246,1.708746443,0.876342038,DB0045110061920_,0.13199881,-0.082404305,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,665858,DB09073,10013700,107,20153,8,782,0.080015367,0.519008473,0.252876656,1.237467253,0.178434201,DB0907310013700_,1.723535365,-0.655835069,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,palbociclib,DB09073
,665893,DB09029,10013700,94,11250,27,7243,0.000111029,2.241360056,1.446079002,3.581657534,0.000872724,DB0902910013700_,7.04389095,0.80708285,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,secukinumab,DB09029
,665913,DB09029,10053762,160,11184,83,7187,0.127831365,1.238740634,0.942765594,1.637797624,0.252587667,DB0902910053762_,1.375996896,0.214095245,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,666196,DB06605,10061623,64,14009,60,12973,1,0.987783118,0.682996958,1.430291944,1,DB0660510061623_,0,-0.012292122,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,666358,DB09071,10013709,236,748,228,554,0.014409451,0.766755123,0.616315594,0.953854333,0.047698812,DB0907110013709_,3.042848781,-0.265587794,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tasimelteon,DB09071
,666403,DB01012,10057374,59,10573,37,8648,0.218229728,1.304251512,0.849424183,2.025884864,0.371418855,DB0101210057374_,0.990424864,0.265629322,NA,10057374,Rehabilitation therapy,10042613,Surgical and medical procedures,Surg,cinacalcet,DB01012
,667139,DB05829,10005393,55,1551,8,201,0.690174892,0.891041174,0.414006978,2.198049301,0.813113235,DB0582910005393_,0.206884899,-0.115364641,NA,10005393,Blood calcium abnormal,10022891,Investigations,Inv,parathyroid hormone,DB05829
,667140,DB05829,10028334,140,1466,7,202,0.006447402,2.754720386,1.27677226,7.077888105,0.025071374,DB0582910028334_,3.686028579,1.013315944,female,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,parathyroid hormone,DB05829
,667141,DB05829,10028813,64,1542,6,203,0.566596042,1.404003119,0.600051746,4.018841244,0.717941428,DB0582910028813_,0.331367291,0.339327527,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,parathyroid hormone,DB05829
,667496,DB05679,10046306,45,6886,25,4884,0.394519874,1.27665095,0.765117308,2.175599655,0.564443441,DB0567910046306_,0.571915094,0.244240203,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,ustekinumab,DB05679
,667531,DB09035,10021143,58,4668,70,6620,0.368321733,1.175030516,0.813347551,1.691975111,0.538039422,DB0903510021143_,0.619823446,0.161294118,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nivolumab,DB09035
,667556,DB09035,10047895,39,4687,76,6614,0.106375159,0.724156585,0.478209471,1.081178811,0.220701795,DB0903510047895_,1.510942831,-0.322747632,NA,10047895,Weight decreased,10022891,Investigations,Inv,nivolumab,DB09035
,667690,DB00433,10017412,33,7623,21,5999,0.493877252,1.236632517,0.693652489,2.251675064,0.656562997,DB0043310017412_,0.420736632,0.212391973,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,prochlorperazine,DB00433
,667813,DB01238,10040979,37,5213,14,3488,0.084442192,1.768215603,0.932018039,3.546288737,0.185791908,DB0123810040979_,1.683128006,0.569970904,NA,10040979,Sleep apnoea syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,aripiprazole,DB01238
,667878,DB09073,10033425,468,19792,7,783,0.004738823,2.644883674,1.26741102,6.638710408,0.0195849,DB0907310033425_,3.932996441,0.972627085,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,palbociclib,DB09073
,667980,DB09065,10047899,38,714,80,1857,0.29536727,1.235342176,0.808545124,1.859105803,0.461283957,DB0906510047899_,0.773741466,0.211347997,NA,10047899,Weight increased,10022891,Investigations,Inv,cobicistat,DB09065
,668228,DB09038,10033645,45,2203,51,2490,1,0.997303662,0.649960712,1.525782487,1,DB0903810033645_,0,-0.00269998,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,empagliflozin,DB09038
,668251,DB00687,10019063,19,967,53,1032,0.000261904,0.382724916,0.212341018,0.662874238,0.001804968,DB0068710019063_,6.317212384,-0.960438783,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,fludrocortisone,DB00687
,668282,DB01238,10069326,35,5215,33,3469,0.171553496,0.705555712,0.424944645,1.173826574,0.312853247,DB0123810069326_,1.162021058,-0.348769543,NA,10069326,Product substitution issue,10077536,Product issues,Prod,aripiprazole,DB01238
,668411,DB00497,10048865,30,19237,38,16337,0.113284767,0.670474051,0.400967987,1.111826327,0.231016728,DB0049710048865_,1.465265158,-0.399770277,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,oxycodone,DB00497
,668412,DB00695,10048865,85,27964,69,20459,0.567532601,0.901273064,0.647970607,1.257414938,0.718695079,DB0069510048865_,0.330318101,-0.103947,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,furosemide,DB00695
,668415,DB00761,10048865,52,15255,32,8593,0.733009297,0.915352484,0.577748798,1.470658758,0.845068943,DB0076110048865_,0.168337065,-0.08844606,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,potassium chloride,DB00761
,668592,DB09071,10019211,67,917,46,736,0.493395636,1.168926403,0.780670344,1.76309271,0.656109302,DB0907110019211_,0.421427884,0.156085723,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,tasimelteon,DB09071
,668737,DB08931,10046306,62,6515,22,2424,0.902469937,1.048519011,0.633887485,1.795647376,0.957195726,DB0893110046306_,0.043747388,0.047378702,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,riociguat,DB08931
,668804,DB00921,10076308,59,5786,101,4802,9.09494002556491e-06,0.484841068,0.344719234,0.676721102,0.000100046,DB0092110076308_,9.209878045,-0.723934137,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,buprenorphine,DB00921
,668879,DB06273,10065154,91,5004,21,1389,0.489636645,1.202802395,0.738851001,2.04385645,0.65297307,DB0627310065154_,0.426219391,0.184654163,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,tocilizumab,DB06273
,668915,DB06273,10021789,101,4994,25,1385,0.66362405,1.120404762,0.713995967,1.819948332,0.79510259,DB0627310021789_,0.229284129,0.113690014,NA,10021789,Infection,10021881,Infections and infestations,Infec,tocilizumab,DB06273
,670238,DB01137,10061284,40,7732,17,5576,0.079546102,1.696775877,0.939214083,3.195485978,0.177666592,DB0113710061284_,1.727846564,0.528729907,NA,10061284,Mental disorder,10037175,Psychiatric disorders,Psych,levofloxacin,DB01137
,671843,DB01065,10033775,70,4261,17,3034,2.32824512329189e-05,2.931511934,1.702844321,5.325297179,0.000227333,DB0106510033775_,8.389096625,1.075518309,female,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,melatonin,DB01065
,671931,DB08820,10012735,62,4339,64,3481,0.175460568,0.77721801,0.537510696,1.123185614,0.317947056,DB0882010012735_,1.145870401,-0.252034389,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ivacaftor,DB08820
,671936,DB08820,10040753,80,4321,49,3496,0.130010922,1.320886734,0.911525006,1.930958738,0.25573128,DB0882010040753_,1.363628074,0.278303279,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,ivacaftor,DB08820
,671937,DB11065,10040753,41,3145,36,2652,0.908527207,0.960350019,0.596769107,1.551475823,0.959033459,DB1106510040753_,0.041829315,-0.040457458,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,pancrelipase amylase,DB11065
,671939,DB08820,10047899,38,4363,16,3529,0.027878566,1.920840602,1.043788167,3.696421606,0.079959419,DB0882010047899_,2.526236035,0.652762904,NA,10047899,Weight increased,10022891,Investigations,Inv,ivacaftor,DB08820
,672787,DB01073,10066274,39,1026,60,1590,1,1.007308332,0.650063952,1.545377824,1,DB0107310066274_,0,0.007281755,NA,10066274,Cytopenia,10005329,Blood and lymphatic system disorders,Blood,fludarabine,DB01073
,673560,DB00668,10012378,53,10038,13,4290,0.079363386,1.742319589,0.935759268,3.487808027,0.177363993,DB0066810012378_,1.729551202,0.555217323,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,epinephrine,DB00668
,676078,DB00482,10076308,62,8197,21,3050,0.804533636,1.098533521,0.659033125,1.901026581,0.894398859,DB0048210076308_,0.111603452,0.093976127,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,celecoxib,DB00482
,676080,DB01192,10076308,39,729,43,511,0.049767511,0.635993341,0.39526636,1.020542985,0.124602469,DB0119210076308_,2.082626859,-0.452567187,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,oxymorphone,DB01192
,676889,DB00153,10061822,40,7383,16,3423,0.668319239,1.159057148,0.633718898,2.220292236,0.798507747,DB0015310061822_,0.225010609,0.147606871,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,676946,DB01137,10029202,35,7737,30,5563,0.529105376,0.838862927,0.499638689,1.416338991,0.686385096,DB0113710029202_,0.376316444,-0.175707963,NA,10029202,Nervous system disorder,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,677357,DB00190,10020772,41,3256,54,4620,0.7536366,1.077316602,0.697983519,1.651660742,0.86144411,DB0019010020772_,0.149145101,0.074473322,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,carbidopa,DB00190
,677507,DB01240,10053762,45,5706,10,1566,0.624100468,1.234978781,0.61179765,2.754763507,0.764011867,DB0124010053762_,0.269171957,0.211053789,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,epoprostenol,DB01240
,677628,DB06723,10064848,72,958,37,573,0.538469393,1.163765651,0.761074064,1.805020515,0.694351845,DB0672310064848_,0.364776466,0.151660998,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,aluminum hydroxide,DB06723
,677845,DB00404,10017533,51,19841,6,9856,0.000109558,4.221714011,1.811024275,12.04427579,0.000862326,DB0040410017533_,7.055877296,1.440241209,female,10017533,Fungal infection,10021881,Infections and infestations,Infec,alprazolam,DB00404
,678265,DB00203,10076308,48,13830,69,8869,1.58345306676519e-05,0.446124239,0.301742317,0.654905962,0.000162329,DB0020310076308_,8.725887622,-0.807157802,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,678373,DB00190,10060933,30,3267,33,4641,0.368733271,1.291370638,0.759124473,2.188947203,0.538378226,DB0019010060933_,0.619193943,0.255704164,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,678735,DB00227,10010264,49,2418,19,1784,0.018218792,1.902467854,1.095347336,3.43437678,0.057389711,DB0022710010264_,2.857890236,0.643151914,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,lovastatin,DB00227
,678815,DB00959,10027175,61,8017,22,4980,0.030834297,1.722294498,1.040998129,2.949572431,0.086559143,DB0095910027175_,2.446927365,0.543657412,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,679048,DB00343,10076309,46,8690,26,5069,1,1.032016633,0.62381643,1.741487114,1,DB0034310076309_,0,0.031514784,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,679365,DB00864,10017944,32,6837,32,8360,0.451287553,1.222737629,0.724478118,2.063700994,0.618945647,DB0086410017944_,0.479737817,0.201092303,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,tacrolimus,DB00864
,680384,DB00455,10029148,47,9354,18,5100,0.241585864,1.42360057,0.810351163,2.607387684,0.399665446,DB0045510029148_,0.917127466,0.353189275,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,loratadine,DB00455
,680859,DB06262,10019303,71,3729,25,4289,7.77586553902585e-08,3.266048113,2.039546671,5.390554245,1.44189506661936e-06,DB0626210019303_,13.44955229,1.183580726,female,10019303,Heart rate increased,10022891,Investigations,Inv,droxidopa,DB06262
,680947,DB00313,10038695,38,1201,14,1503,5.37017198482267e-05,3.395372426,1.788328796,6.818117765,0.000469031,DB0031310038695_,7.664841048,1.222413453,female,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,valproic acid,DB00313
,681349,DB00374,10053762,547,17169,242,5482,5.03364472000685e-05,0.721726433,0.617282812,0.845752758,0.000444588,DB0037410053762_,7.71836283,-0.326109113,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,681821,DB08895,10022095,259,27855,22,6624,1.61338516690616e-07,2.799560749,1.807917391,4.54917803,2.80104551599263e-06,DB0889510022095_,12.78551781,1.029462529,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,681944,DB08904,10066901,155,11455,56,3503,0.288005751,0.846407775,0.61819119,1.173386692,0.452995312,DB0890410066901_,0.791873502,-0.166754032,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,682012,DB00813,10029282,6,10566,44,10124,1.17550759531466e-08,0.130670814,0.045489547,0.307973842,2.60195512781859e-07,DB0081310029282_,15.16183252,-2.035073991,male,10029282,Neuroleptic malignant syndrome,10029205,Nervous system disorders,Nerv,fentanyl,DB00813
,682333,DB00734,10013916,27,4023,36,4866,0.799727942,0.90719771,0.528713811,1.53944635,0.891736807,DB0073410013916_,0.11458425,-0.09739487,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,risperidone,DB00734
,682528,DB09038,10016256,44,2204,65,2476,0.174838976,0.76050795,0.504297018,1.137513228,0.317247168,DB0903810016256_,1.1480741,-0.273768714,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,empagliflozin,DB09038
,682929,DB05679,10057362,39,6892,34,4875,0.404875224,0.811382955,0.498265008,1.327092301,0.574598848,DB0567910057362_,0.554083138,-0.209015136,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,ustekinumab,DB05679
,683555,DB00588,10048010,49,16475,12,8456,0.02059625,2.095767104,1.097838939,4.331393165,0.063255526,DB0058810048010_,2.760572788,0.739919646,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,684045,DB08820,10047700,51,4350,48,3497,0.476710627,0.854171399,0.562988919,1.297747876,0.642116835,DB0882010047700_,0.442985006,-0.157623404,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ivacaftor,DB08820
,685451,DB08904,10016173,113,11497,28,3531,0.368612774,1.239440669,0.811927178,1.951277397,0.538285042,DB0890410016173_,0.619367041,0.214660205,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,certolizumab pegol,DB08904
,685845,DB04951,10000087,52,1830,65,2992,0.177136641,1.307880375,0.886058205,1.922391055,0.320189568,DB0495110000087_,1.13884206,0.268407792,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,pirfenidone,DB04951
,686106,DB00864,10012818,39,6830,12,8380,6.55838723545689e-06,3.987219638,2.043365015,8.371073615,7.49672574403064e-05,DB0086410012818_,9.498459107,1.383094155,female,10012818,Diffuse large B-cell lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,tacrolimus,DB00864
,686130,DB09073,10037844,645,19615,6,784,1.28117802399536e-05,4.296546535,1.954148879,11.78843481,0.000135,DB0907310037844_,8.910235353,1.457811569,female,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,palbociclib,DB09073
,687624,DB06168,10064355,46,563,21,379,0.157609944,1.474037564,0.846121867,2.645066449,0.294273148,DB0616810064355_,1.223246869,0.388005278,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,canakinumab,DB06168
,688558,DB01307,10047571,44,2480,27,2042,0.279272463,1.341729756,0.809375374,2.261813901,0.443117028,DB0130710047571_,0.813921372,0.293959644,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,insulin detemir,DB01307
,688768,DB00087,10003988,42,1327,16,731,0.264894803,1.445787024,0.789399185,2.774980658,0.426835855,DB0008710003988_,0.851355754,0.368653827,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,alemtuzumab,DB00087
,689442,DB00734,10064685,32,4018,49,4853,0.314692944,0.788798463,0.487856776,1.259363729,0.482288341,DB0073410064685_,0.729213125,-0.237244424,NA,10064685,Device occlusion,10077536,Product issues,Prod,risperidone,DB00734
,689468,DB09073,10016288,94,20166,7,783,0.106365888,0.521415694,0.242248198,1.336785472,0.220701795,DB0907310016288_,1.510942831,-0.651207679,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,palbociclib,DB09073
,689516,DB13867,10020751,44,4506,21,2533,0.604511669,1.177764827,0.683733136,2.090328568,0.747833355,DB1386710020751_,0.290575113,0.163618427,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,fluticasone,DB13867
,689963,DB00704,10002855,188,4168,192,5002,0.127602572,1.175071271,0.951714955,1.450717179,0.252249359,DB0070410002855_,1.377337163,0.161328802,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,689967,DB00704,10003549,80,4276,106,5088,0.503765288,0.898066102,0.661264205,1.215611761,0.664885214,DB0070410003549_,0.408140863,-0.107511603,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,689983,DB00704,10017577,67,4289,102,5092,0.119714829,0.779863673,0.56271153,1.074890684,0.240969811,DB0070410017577_,1.423083619,-0.248636153,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,689998,DB00704,10025482,201,4155,227,4967,0.585076861,1.058468603,0.867065206,1.291391032,0.732666566,DB0070410025482_,0.31106457,0.05682315,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,690091,DB09073,10054112,122,20138,8,782,0.1579093,0.59221044,0.289792663,1.407685219,0.294664628,DB0907310054112_,1.221917422,-0.523893235,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,palbociclib,DB09073
,690350,DB05676,10022086,60,47069,10,25319,0.000140211,3.227427719,1.638810973,7.073501227,0.001064695,DB0567610022086_,6.845067264,1.171685448,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,690399,DB00704,10003988,81,4275,69,5125,0.039042505,1.407258732,1.005362766,1.97446715,0.10374282,DB0070410003988_,2.26584033,0.34164365,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,naltrexone,DB00704
,690452,DB00704,10047895,56,4300,66,5128,1,1.011867911,0.694104204,1.470643807,1,DB0070410047895_,0,0.01179804,NA,10047895,Weight decreased,10022891,Investigations,Inv,naltrexone,DB00704
,690668,DB00635,10060931,14,33039,64,23730,5.36851238157453e-13,0.157146611,0.081316933,0.283266479,2.48873629540893e-11,DB0063510060931_,24.41666095,-1.850576084,male,10060931,Adenovirus infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,691763,DB08868,10020751,49,9153,19,2492,0.184672339,0.702169164,0.40503016,1.265434384,0.329752459,DB0886810020751_,1.10941303,-0.35358093,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,fingolimod,DB08868
,692915,DB00704,10057880,41,4315,21,5173,0.001269474,2.340402618,1.349010514,4.175841813,0.006692365,DB0070410057880_,5.006787984,0.850322974,NA,10057880,Injection site nodule,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,692920,DB09027,10065154,20,5159,34,7118,0.492441207,0.811616617,0.442131961,1.452900339,0.655333373,DB0902710065154_,0.422611206,-0.208727196,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,ledipasvir,DB09027
,692987,DB09073,10065154,370,19890,9,781,0.172986209,1.614257588,0.836743883,3.571975763,0.314765325,DB0907310065154_,1.155927917,0.478875153,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,palbociclib,DB09073
,693042,DB00254,10017885,48,5887,18,3370,0.157101059,1.526462171,0.870097646,2.793113502,0.29361636,DB0025410017885_,1.225481261,0.422952751,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,doxycycline,DB00254
,693148,DB08904,10050584,112,11498,13,3546,0.000272647,2.656969592,1.489810878,5.15096543,0.001865589,DB0890410050584_,6.284178355,0.977186222,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,certolizumab pegol,DB08904
,693229,DB00230,10048706,51,19623,10,8641,0.017224024,2.245734504,1.126642825,4.964258578,0.054953385,DB0023010048706_,2.901269999,0.809032641,NA,10048706,Joint range of motion decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,pregabalin,DB00230
,693408,DB00656,10022081,71,11942,14,6605,0.000146103,2.804820535,1.56547364,5.394185407,0.001101636,DB0065610022081_,6.810958589,1.031339557,female,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,trazodone,DB00656
,693633,DB00704,10013663,211,4145,340,4854,0.000415617,0.72676526,0.606013866,0.869974919,0.002644516,DB0070410013663_,5.935267304,-0.319151742,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,693812,DB08906,10054112,39,2154,19,1139,0.889379614,1.085379572,0.608985065,1.998305567,0.954019727,DB0890610054112_,0.04707093,0.081929762,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,fluticasone furoate,DB08906
,694115,DB06262,10028334,48,3752,28,4286,0.00525883,1.958089574,1.20113778,3.248161143,0.021292104,DB0626210028334_,3.849418993,0.671969291,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,droxidopa,DB06262
,694185,DB00904,10037162,49,23020,7,14449,2.45606104185845e-05,4.393561713,1.97895891,11.50065757,0.000237869,DB0090410037162_,8.343791728,1.480140222,female,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,ondansetron,DB00904
,694399,DB01015,10043645,16,9871,40,9341,0.000700822,0.378538312,0.197777948,0.691792899,0.004095854,DB0101510043645_,5.497780126,-0.971437992,NA,10043645,Thrombotic microangiopathy,10005329,Blood and lymphatic system disorders,Blood,sulfamethoxazole,DB01015
,694517,DB00541,10041101,33,3101,24,4273,0.02128886,1.894464263,1.083835151,3.35713393,0.064965192,DB0054110041101_,2.733903665,0.638936088,NA,10041101,Small intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,vincristine,DB00541
,694611,DB00916,10054112,40,5283,11,2420,0.171916373,1.665621676,0.83695318,3.60580636,0.313328378,DB0091610054112_,1.160503506,0.510198433,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,metronidazole,DB00916
,694641,DB01065,10001551,30,4301,41,3010,0.005289425,0.512114598,0.308036837,0.842564272,0.02139506,DB0106510001551_,3.844595235,-0.669206854,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,melatonin,DB01065
,694650,DB01065,10003481,29,4302,30,3021,0.145415542,0.678874173,0.392258297,1.173250602,0.277638377,DB0106510003481_,1.281435816,-0.387319482,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,melatonin,DB01065
,695033,DB09045,10022067,51,2298,31,1693,0.430929652,1.211978907,0.757092567,1.96863631,0.599374849,DB0904510022067_,0.511868086,0.192254484,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,dulaglutide,DB09045
,695083,DB00951,10013709,40,612,28,537,0.384280822,1.253269082,0.742717552,2.140569142,0.554320129,DB0095110013709_,0.590012909,0.225755403,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,isoniazid,DB00951
,695248,DB09122,10048393,90,1168,20,317,0.470119477,1.221166561,0.732175952,2.127669911,0.636372976,DB0912210048393_,0.451970447,0.199806599,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,peginterferon beta-1a,DB09122
,695286,DB00820,10010144,7,11908,44,5772,3.5287371799405e-15,0.077114011,0.029297273,0.172725656,2.21103353455866e-13,DB0082010010144_,29.14014614,-2.562470291,male,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,tadalafil,DB00820
,695315,DB09073,10011906,790,19470,66,724,3.33727314111695e-08,0.445116023,0.341828549,0.587589988,6.67581617307908e-07,DB0907310011906_,14.21960418,-0.809420305,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,palbociclib,DB09073
,695493,DB01067,10012671,29,4332,38,4785,0.540140634,0.842978053,0.500499878,1.406187632,0.695721888,DB0106710012671_,0.362805284,-0.170814356,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,glipizide,DB01067
,695513,DB00736,10061481,214,10377,134,5419,0.110125737,0.834002133,0.667173636,1.045565413,0.226242135,DB0073610061481_,1.486149459,-0.181519319,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,esomeprazole,DB00736
,695586,DB06605,10019974,30,14043,27,13006,1,1.029065507,0.590936718,1.800023367,1,DB0660510019974_,0,0.028651116,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,apixaban,DB06605
,695848,DB00005,10065154,926,127156,325,42094,0.37549936,0.943210932,0.82995991,1.074111535,0.545334034,DB0000510065154_,0.606356766,-0.058465339,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,696401,DB00586,10019974,42,7067,9,2796,0.117709084,1.846235961,0.884325865,4.319507534,0.237751817,DB0058610019974_,1.436527937,0.613148951,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,diclofenac,DB00586
,696441,DB09073,10037660,370,19890,10,780,0.337715479,1.450971795,0.775883605,3.063567888,0.506838187,DB0907310037660_,0.679563485,0.372233536,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,palbociclib,DB09073
,696944,DB09029,10037153,1157,10187,813,6457,0.033657681,0.902049864,0.819474384,0.993226493,0.09269616,DB0902910037153_,2.378428233,-0.103085479,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,698349,DB01024,10016256,67,2144,40,2080,0.018409146,1.624812201,1.076795501,2.47957179,0.057877448,DB0102410016256_,2.849427475,0.485392241,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,mycophenolic acid,DB01024
,698496,DB09029,10020751,157,11187,57,7213,0.000173733,1.775880907,1.301636613,2.452607517,0.001280769,DB0902910020751_,6.660294241,0.574296585,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,secukinumab,DB09029
,698497,DB09029,10037844,422,10922,240,7030,0.13364527,1.131785003,0.960775514,1.33548253,0.260830555,DB0902910037844_,1.343884297,0.123796035,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,698744,DB06605,10021143,75,13998,55,12978,0.217894021,1.264258538,0.880141451,1.825955437,0.371074465,DB0660510021143_,0.991352522,0.234485814,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,698896,DB00287,10066901,280,1121,188,629,0.09467091,0.835766581,0.674778931,1.036527223,0.202747778,DB0028710066901_,1.595792543,-0.179405915,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,travoprost,DB00287
,698897,DB00484,10066901,356,2151,248,1532,0.823818736,1.022387236,0.855435664,1.223176715,0.906597257,DB0048410066901_,0.098056966,0.022140321,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,brimonidine,DB00484
,698898,DB00814,10066901,36,8251,17,3398,0.650724938,0.872129963,0.476564831,1.658215444,0.785249518,DB0081410066901_,0.241753754,-0.136816826,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,meloxicam,DB00814
,698899,DB01220,10054112,72,1222,102,1034,0.001201031,0.597420813,0.430491479,0.825618414,0.006412574,DB0122010054112_,5.049494529,-0.515133535,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,rifaximin,DB01220
,699058,DB09029,10028813,281,11063,97,7173,3.45411711551057e-08,1.878225471,1.482953059,2.395759717,6.8885787846127e-07,DB0902910028813_,14.18823086,0.630327433,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,699086,DB00863,10037162,48,10625,13,5827,0.022158743,2.024870538,1.078690698,4.077608406,0.066993623,DB0086310037162_,2.703157843,0.705505767,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,699333,DB09033,10061380,53,2571,43,1626,0.244666984,0.779575305,0.508878579,1.200128883,0.403416974,DB0903310061380_,0.907784578,-0.249005989,NA,10061380,Therapeutic reaction time decreased,10018065,General disorders and administration site conditions,Genrl,vedolizumab,DB09033
,699386,DB04951,10000059,78,1804,89,2968,0.023027051,1.44173352,1.043801514,1.988152698,0.068964398,DB0495110000059_,2.674164881,0.365846223,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,pirfenidone,DB04951
,699391,DB08932,10000381,47,19396,11,6586,0.293726344,1.450771743,0.741090087,3.103923012,0.459463622,DB0893210000381_,0.77769551,0.372095652,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,701736,DB00853,10076309,25,1796,30,2236,0.892336646,1.037498431,0.58280156,1.832178115,0.955096839,DB0085310076309_,0.045942542,0.036812461,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,temozolomide,DB00853
,702644,DB00316,10075192,31,65443,46,36907,2.54298644323534e-05,0.380059898,0.232926231,0.612518584,0.00024503,DB0031610075192_,8.31412876,-0.967426411,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,acetaminophen,DB00316
,702646,DB00338,10075192,28,33646,41,22231,0.001222803,0.451233477,0.268667449,0.747758581,0.006493864,DB0033810075192_,5.036897477,-0.795770386,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,omeprazole,DB00338
,704215,DB00152,10028813,40,791,25,839,0.043108814,1.696554285,0.993791316,2.947250838,0.111896032,DB0015210028813_,2.190185122,0.528599303,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,thiamine,DB00152
,704250,DB00863,10037400,36,10637,17,5823,0.668212439,1.159234631,0.633873522,2.202926068,0.798452731,DB0086310037400_,0.22507951,0.147759987,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ranitidine,DB00863
,704340,DB06589,10042128,28,2002,30,2623,0.505465755,1.222784651,0.70143851,2.12556681,0.666365919,DB0658910042128_,0.405916332,0.201130759,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,pazopanib,DB06589
,704455,DB08895,10007697,57,28057,9,6637,0.345854959,1.498152009,0.735854228,3.444153503,0.515296661,DB0889510007697_,0.663012504,0.404232354,NA,10007697,Carpal tunnel syndrome,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,704496,DB08895,10031161,171,27943,33,6613,0.325814461,1.226322393,0.840014502,1.840320564,0.49430222,DB0889510031161_,0.704608168,0.204019766,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,704662,DB00334,10016288,43,2806,29,2783,0.123098173,1.470498495,0.894312552,2.449963394,0.245834847,DB0033410016288_,1.403095321,0.385601455,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,olanzapine,DB00334
,704664,DB01065,10016288,32,4299,36,3015,0.062780547,0.623456955,0.373940509,1.035162625,0.148645378,DB0106510016288_,1.90619182,-0.472475553,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,melatonin,DB01065
,705216,DB06285,10017076,98,8752,10,1096,0.644888674,1.227183652,0.637284547,2.647243811,0.780733658,DB0628510017076_,0.247521215,0.20472183,NA,10017076,Fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,teriparatide,DB06285
,705465,DB01377,10001053,30,3766,21,2649,1,1.004854793,0.555117884,1.851076567,1,DB0137710001053_,0,0.004843047,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,magnesium oxide,DB01377
,705600,DB01068,10003481,43,13720,13,6827,0.119831601,1.64585389,0.867999751,3.33838496,0.241130996,DB0106810003481_,1.422414943,0.498259332,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,clonazepam,DB01068
,706198,DB08906,10021097,32,2161,25,1133,0.159578526,0.671156282,0.383280352,1.187616535,0.296873208,DB0890610021097_,1.214450141,-0.39875326,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,fluticasone furoate,DB08906
,706318,DB08904,10071408,296,11314,9,3550,3.99833186507887e-24,10.3187968,5.354435857,22.81407011,5.77451390514275e-22,DB0890410071408_,48.90341797,2.333967164,female,10071408,Maternal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,certolizumab pegol,DB08904
,706563,DB01611,10037400,57,11856,10,2351,0.869197005,1.130267788,0.57102541,2.486251832,0.941834294,DB0161110037400_,0.059925929,0.122454585,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,hydroxychloroquine,DB01611
,706745,DB06403,10006784,56,21415,14,6647,0.573414408,1.241544886,0.681569292,2.416761508,0.723293325,DB0640310006784_,0.323940434,0.21635648,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,ambrisentan,DB06403
,706900,DB09140,10028836,44,3697,9,1789,0.017425318,2.365455726,1.136429206,5.523495891,0.055457619,DB0914010028836_,2.892136173,0.860970699,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,oxygen,DB09140
,707400,DB06403,10003662,53,21418,11,6650,0.242510321,1.495933144,0.771726012,3.178290794,0.400703029,DB0640310003662_,0.914534703,0.402750188,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,ambrisentan,DB06403
,707949,DB08931,10007815,55,6522,16,2430,0.424006122,1.280710397,0.721556875,2.399427477,0.592800282,DB0893110007815_,0.522897729,0.247414922,NA,10007815,Catheterisation cardiac,10022891,Investigations,Inv,riociguat,DB08931
,708407,DB08895,10039203,59,28055,8,6638,0.161311862,1.744932712,0.82967938,4.230964913,0.299237068,DB0889510039203_,1.20651915,0.556715994,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,708428,DB08895,10042609,124,27990,20,6626,0.136132064,1.467687245,0.909798093,2.48777807,0.264301933,DB0889510042609_,1.330663143,0.383687859,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,tofacitinib,DB08895
,708457,DB00316,10049548,47,65427,18,36935,0.195980332,1.474024853,0.839954767,2.697131155,0.344237564,DB0031610049548_,1.066423266,0.387996655,NA,10049548,Knee operation,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,709249,DB00820,10016334,75,11840,24,5792,0.085195413,1.528682348,0.953049449,2.534942426,0.187082947,DB0082010016334_,1.676203194,0.424406154,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,709262,DB08906,10008479,38,2155,12,1146,0.134145577,1.683751629,0.85724518,3.553920961,0.261517078,DB0890610008479_,1.341255691,0.521024416,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,fluticasone furoate,DB08906
,709945,DB09078,10003549,35,758,86,970,0.001205783,0.520975708,0.337218487,0.790214243,0.006429455,DB0907810003549_,5.046865458,-0.652051865,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,lenvatinib,DB09078
,709948,DB09078,10012174,38,755,70,986,0.108798304,0.709079419,0.459242013,1.080624523,0.224224826,DB0907810012174_,1.495106045,-0.343787743,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,lenvatinib,DB09078
,710479,DB00814,10054112,44,8243,22,3393,0.497178533,0.823282951,0.482073995,1.444667629,0.659334413,DB0081410054112_,0.416524417,-0.194455333,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,meloxicam,DB00814
,710997,DB00437,10062355,44,6877,58,11488,0.259278021,1.267235876,0.835447814,1.910282543,0.420388169,DB0043710062355_,0.866576784,0.236838053,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,711602,DB06262,10052904,27,3773,30,4284,1,1.021894534,0.58338629,1.782224366,1,DB0626210052904_,0,0.021658291,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,droxidopa,DB06262
,711919,DB09292,10008479,69,4460,114,8148,0.533627831,1.105746976,0.805973337,1.507659643,0.690292947,DB0929210008479_,0.370639211,0.100521103,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,711920,DB09292,10042772,42,4487,100,8162,0.158166029,0.764002687,0.518669116,1.108173647,0.295015507,DB0929210042772_,1.220727359,-0.269183973,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,712037,DB01377,10005557,39,3757,28,2642,1,0.979482027,0.585827027,1.657225037,1,DB0137710005557_,0,-0.020731391,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,magnesium oxide,DB01377
,712070,DB14500,10065154,32,7777,21,4052,0.468426984,0.793974868,0.443239871,1.450750833,0.634915729,DB1450010065154_,0.454262998,-0.230703471,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,potassium,DB14500
,712247,DB00512,10052015,33,4704,40,5058,0.639660764,0.887096574,0.541075243,1.445398356,0.776711932,DB0051210052015_,0.252685741,-0.119801426,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,vancomycin,DB00512
,713151,DB13961,10013538,39,9418,19,6395,0.283634614,1.393746658,0.785402195,2.556001273,0.44803701,DB1396110013538_,0.802879439,0.331995559,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,fish oil,DB13961
,713620,DB06643,10062262,47,52374,6,7509,1,1.123108771,0.478991266,3.215731607,1,DB0664310062262_,0,0.116100528,NA,10062262,Spinal operation,10042613,Surgical and medical procedures,Surg,denosumab,DB06643
,713950,DB00761,10047340,42,15265,18,8607,0.349797036,1.315613173,0.740527692,2.429687354,0.519385121,DB0076110047340_,0.655109627,0.274302848,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,potassium chloride,DB00761
,714342,DB00158,10073317,66,16749,20,8084,0.082897182,1.59273642,0.952736371,2.775850019,0.183223158,DB0015810073317_,1.697050424,0.465453556,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,714534,DB00381,10048010,47,29313,24,22863,0.094631985,1.52740927,0.915014213,2.612484192,0.202703398,DB0038110048010_,1.596011461,0.423573013,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,715194,DB09071,10000125,42,942,31,751,0.810276611,1.080109605,0.655869531,1.795904799,0.897897163,DB0907110000125_,0.107699735,0.077062522,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,tasimelteon,DB09071
,715195,DB09071,10029412,43,941,49,733,0.084477739,0.683735021,0.437844522,1.064296874,0.185839493,DB0907110029412_,1.682871917,-0.380184833,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,tasimelteon,DB09071
,716260,DB09073,10012174,251,20009,10,780,0.869762538,0.978456034,0.52045291,2.073919854,0.942090076,DB0907310012174_,0.059654387,-0.021779425,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,palbociclib,DB09073
,716784,DB08931,10056819,62,6515,18,2428,0.379622597,1.283618292,0.747692934,2.310603188,0.549682144,DB0893110056819_,0.598415088,0.24968288,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,riociguat,DB08931
,716877,DB06186,10020772,25,2184,30,3616,0.263774129,1.379616184,0.775808539,2.433917161,0.425619272,DB0618610020772_,0.854210061,0.321805333,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ipilimumab,DB06186
,717148,DB00722,10021138,16,25387,34,25998,0.015675735,0.481922947,0.248324946,0.897485293,0.051029374,DB0072210021138_,2.975353848,-0.729971039,NA,10021138,Hypovolaemic shock,10047065,Vascular disorders,Vasc,lisinopril,DB00722
,718052,DB00482,10054112,36,8223,27,3044,0.006666318,0.493591429,0.290881934,0.846921676,0.025773945,DB0048210054112_,3.658391172,-0.70604717,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,celecoxib,DB00482
,718128,DB06605,10042609,58,14015,48,12985,0.626515525,1.119517209,0.749935809,1.678089759,0.766094184,DB0660510042609_,0.266450162,0.112897529,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,apixaban,DB06605
,718421,DB09073,10017413,525,19735,6,784,0.00043824,3.475934729,1.578977328,9.543152494,0.002766032,DB0907310017413_,5.890341315,1.24586343,female,10017413,Full blood count decreased,10022891,Investigations,Inv,palbociclib,DB09073
,718538,DB09107,10067482,124,1091,145,858,0.0026087,0.672670072,0.516117332,0.875695963,0.012063632,DB0910710067482_,4.417560002,-0.396500305,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,methoxy polyethylene glycol-epoetin beta,DB09107
,718708,DB01222,10056871,54,9220,16,5389,0.017611273,1.972570376,1.110885941,3.696249558,0.055944444,DB0122210056871_,2.883396148,0.679337452,NA,10056871,Device failure,10077536,Product issues,Prod,budesonide,DB01222
,719030,DB08868,10010253,62,9140,23,2488,0.231411101,0.733805078,0.44713581,1.243682158,0.387636735,DB0886810010253_,0.947686627,-0.309511847,NA,10010253,Concomitant disease aggravated,10018065,General disorders and administration site conditions,Genrl,fingolimod,DB08868
,720365,DB00619,10054112,38,2861,40,2454,0.423526063,0.814888772,0.506930363,1.307933224,0.592337052,DB0061910054112_,0.523679461,-0.204703651,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,imatinib,DB00619
,720442,DB05676,10065154,134,46995,65,25264,0.551585078,1.108253758,0.817783597,1.514892898,0.705570419,DB0567610065154_,0.348748698,0.102785586,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,apremilast,DB05676
,720461,DB00668,10010774,51,10040,18,4285,0.598069611,1.209217108,0.693607949,2.202087024,0.742999711,DB0066810010774_,0.297059623,0.189973132,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,epinephrine,DB00668
,720690,DB01137,10014387,29,7743,45,5548,0.001269044,0.461778387,0.278822057,0.753858835,0.006690766,DB0113710014387_,5.007026944,-0.772670184,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,levofloxacin,DB01137
,720876,DB08881,10012735,45,578,37,774,0.038436756,1.628038211,1.015658259,2.623928158,0.102517517,DB0888110012735_,2.277721602,0.487375738,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,vemurafenib,DB08881
,720939,DB00028,10043521,38,13420,13,5602,0.644951578,1.220172949,0.63518641,2.498216509,0.780773851,DB0002810043521_,0.247469735,0.19899261,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,human immunoglobulin g,DB00028
,720960,DB09107,10037087,239,976,167,836,0.068890332,1.225737306,0.98018189,1.535126287,0.159322721,DB0910710037087_,1.836823442,0.203542546,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,methoxy polyethylene glycol-epoetin beta,DB09107
,721211,DB09037,10020772,44,2482,24,2811,0.004578192,2.076053006,1.231064812,3.580553228,0.01903025,DB0903710020772_,3.961725453,0.730468498,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,pembrolizumab,DB09037
,721231,DB00635,10075611,60,32993,38,23756,0.608620802,1.136852567,0.744621896,1.755190151,0.751196191,DB0063510075611_,0.286088422,0.128263538,NA,10075611,Varicella zoster virus infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,721257,DB00563,10060968,42,46604,17,15331,0.453186394,0.812722153,0.452697072,1.523267807,0.62075637,DB0056310060968_,0.476816592,-0.207365983,NA,10060968,Arthritis infective,10021881,Infections and infestations,Infec,methotrexate,DB00563
,721303,DB09035,10051792,53,4673,88,6602,0.389959886,0.85091719,0.592151103,1.21261734,0.559877094,DB0903510051792_,0.580037994,-0.161440464,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,nivolumab,DB09035
,721495,DB09035,10007515,25,4701,32,6658,0.787726814,1.106468745,0.627743313,1.929852301,0.88501632,DB0903510007515_,0.122149194,0.101173633,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,nivolumab,DB09035
,721659,DB09073,10011224,539,19721,18,772,0.573251162,1.172203784,0.72958238,2.003972906,0.723184315,DB0907310011224_,0.324091159,0.158885553,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,palbociclib,DB09073
,721912,DB06605,10040070,53,14020,38,12995,0.248264074,1.292753156,0.83572212,2.01695433,0.407634768,DB0660510040070_,0.897383682,0.256774174,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,apixaban,DB06605
,721982,DB00207,10062352,36,9044,14,5441,0.188780578,1.546964029,0.813386289,3.107847169,0.335027851,DB0020710062352_,1.093541613,0.43629432,NA,10062352,Respiratory tract infection,10021881,Infections and infestations,Infec,azithromycin,DB00207
,722070,DB01268,10010264,30,2113,42,3088,0.904023439,1.043901849,0.628675767,1.714103939,0.957450283,DB0126810010264_,0.043481484,0.042965471,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,sunitinib,DB01268
,722208,DB00181,10067482,42,9814,30,5841,0.46486773,0.833255812,0.508648541,1.380387186,0.631757386,DB0018110067482_,0.459249842,-0.182414587,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,722210,DB01373,10067482,47,22673,15,7366,1,1.017960845,0.558894146,1.961215867,1,DB0137310067482_,0,0.017801455,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,722347,DB06791,10033371,30,749,21,517,1,0.986083744,0.539256505,1.833927327,1,DB0679110033371_,0,-0.014013995,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,lanreotide,DB06791
,722933,DB01590,10053762,65,4673,55,2812,0.071080628,0.711218655,0.487397534,1.041049938,0.163189301,DB0159010053762_,1.812844395,-0.340775365,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,everolimus,DB01590
,723059,DB06212,10011906,91,583,112,460,0.004344363,0.641324531,0.4679222,0.877170902,0.018260426,DB0621210011906_,4.003019069,-0.444219662,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tolvaptan,DB06212
,723145,DB09073,10033661,132,20128,9,781,0.113302853,0.569112013,0.289379834,1.276942983,0.231035685,DB0907310033661_,1.465183098,-0.563678005,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,palbociclib,DB09073
,723165,DB09035,10033425,27,4699,37,6653,0.899397725,1.033190285,0.604085885,1.746148205,0.956490275,DB0903510033425_,0.044484657,0.032651379,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,nivolumab,DB09035
,723201,DB09029,10025482,374,10970,169,7101,0.000119645,1.432482899,1.188290712,1.732577033,0.000929198,DB0902910025482_,6.981188321,0.359409232,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,723329,DB09029,10029148,47,11297,35,7235,0.498374343,0.860024508,0.542890444,1.373997982,0.660264011,DB0902910029148_,0.415115508,-0.150794393,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,secukinumab,DB09029
,724005,DB08895,10061194,114,28000,17,6629,0.075225557,1.587586805,0.948373514,2.822085308,0.170222431,DB0889510061194_,1.770649278,0.462215131,NA,10061194,Hand deformity,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,724115,DB00425,10022052,47,12648,10,7474,0.002203443,2.77720998,1.383925202,6.168066083,0.010525101,DB0042510022052_,4.553992305,1.021446819,female,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,zolpidem,DB00425
,724741,DB00332,10010264,56,2628,33,1623,0.912329811,1.048007583,0.66653772,1.671424577,0.960594091,DB0033210010264_,0.040203341,0.046890822,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ipratropium,DB00332
,724806,DB09035,10008479,39,4687,53,6637,0.915439213,1.042018998,0.669724761,1.608682497,0.962143444,DB0903510008479_,0.03859173,0.041160175,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,nivolumab,DB09035
,724966,DB09073,10047895,414,19846,6,784,0.008745719,2.725703556,1.235977406,7.494443481,0.031992376,DB0907310047895_,3.442257665,1.00272658,female,10047895,Weight decreased,10022891,Investigations,Inv,palbociclib,DB09073
,725188,DB08932,10040880,43,19400,9,6588,0.204595139,1.622385554,0.779586679,3.787036521,0.354606391,DB0893210040880_,1.036746862,0.48389763,NA,10040880,Skin irritation,10040785,Skin and subcutaneous tissue disorders,Skin,macitentan,DB08932
,725265,DB08932,10064366,62,19381,17,6580,0.517401403,1.238187199,0.71413833,2.260966629,0.677011062,DB0893210064366_,0.390067666,0.213648374,NA,10064366,Extra dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,726733,DB00959,10017944,38,8040,16,4986,0.209034587,1.472812606,0.800888277,2.832425303,0.36006284,DB0095910017944_,1.021476706,0.38717391,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,methylprednisolone,DB00959
,727473,DB00688,10061822,51,6439,20,5358,0.003855137,2.121729065,1.241102419,3.762663066,0.016556209,DB0068810061822_,4.10099406,0.752231353,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,727475,DB01611,10061822,239,11674,31,2330,0.025169893,1.538718248,1.052421317,2.321659421,0.07387122,DB0161110061822_,2.605431976,0.430949763,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,727693,DB01065,10046735,37,4294,25,3026,0.897801208,1.042961449,0.609802293,1.811525383,0.956338178,DB0106510046735_,0.044643686,0.042064214,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,melatonin,DB01065
,728497,DB00287,10047571,35,1366,16,801,0.464871047,1.282575684,0.686277687,2.498362851,0.631757386,DB0028710047571_,0.459249842,0.248870309,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,travoprost,DB00287
,729305,DB09146,10008479,38,750,14,413,0.236263095,1.49420209,0.780465285,3.022004053,0.393455445,DB0914610008479_,0.932787446,0.401592345,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,iron sucrose,DB09146
,729396,DB00368,10040560,27,633,48,750,0.121065574,0.66665196,0.395006678,1.10455592,0.242963055,DB0036810040560_,1.414845884,-0.405487168,NA,10040560,Shock,10047065,Vascular disorders,Vasc,norepinephrine,DB00368
,729591,DB00924,10005191,47,10115,10,4241,0.057320953,1.97052882,0.981515317,4.377944387,0.138411763,DB0092410005191_,1.977522247,0.678301943,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,cyclobenzaprine,DB00924
,729624,DB01224,10009192,52,8056,7,5910,4.97241130541034e-07,5.449203026,2.463278055,14.23392846,7.71090449337527e-06,DB0122410009192_,11.77287506,1.695469364,female,10009192,Circulatory collapse,10047065,Vascular disorders,Vasc,quetiapine,DB01224
,731237,DB00563,10064848,96,46550,34,15314,0.685238514,0.928877307,0.621938471,1.417691147,0.809887557,DB0056310064848_,0.210859859,-0.073778619,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,methotrexate,DB00563
,731244,DB13867,10064848,34,4516,24,2530,0.410801526,0.79370091,0.455873419,1.402273306,0.580143351,DB1386710064848_,0.544480049,-0.231048576,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,fluticasone,DB13867
,731333,DB09037,10011224,46,2480,50,2785,0.917977093,1.0331496,0.674277977,1.579888721,0.963600083,DB0903710011224_,0.037078922,0.032612001,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pembrolizumab,DB09037
,732163,DB00557,10001760,67,5920,9,3058,1.45486273408094e-05,3.84492972,1.905716662,8.786800053,0.000150971,DB0055710001760_,8.798419846,1.346755325,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,hydroxyzine,DB00557
,732218,DB08895,10043224,218,27896,42,6604,0.23581384,1.228766254,0.878802459,1.755101468,0.392972898,DB0889510043224_,0.934014632,0.20601062,NA,10043224,Tenderness,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,732624,DB00490,10010774,50,4020,12,1564,0.154532558,1.620980593,0.848315174,3.353380182,0.290155603,DB0049010010774_,1.237337938,0.483031271,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,buspirone,DB00490
,733046,DB00804,10010264,56,2944,11,888,0.241320643,1.535388071,0.791593497,3.264822879,0.399427795,DB0080410010264_,0.917722269,0.428783164,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,dicyclomine,DB00804
,733379,DB00904,10003662,26,23043,37,14419,0.001635208,0.439716852,0.255539007,0.746368337,0.00824268,DB0090410003662_,4.798429769,-0.821624278,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,ondansetron,DB00904
,733972,DB09035,10003827,14,4712,44,6646,0.007260417,0.448808621,0.226877816,0.835582343,0.027550175,DB0903510003827_,3.591746376,-0.801158716,NA,10003827,Autoimmune hepatitis,10019805,Hepatobiliary disorders,Hepat,nivolumab,DB09035
,734510,DB08906,10022000,47,2146,7,1151,0.000445471,3.600131881,1.610141744,9.469821645,0.002805944,DB0890610022000_,5.876015141,1.280970478,female,10022000,Influenza,10021881,Infections and infestations,Infec,fluticasone furoate,DB08906
,734577,DB00213,10070608,33,18862,33,13388,0.170403663,0.709806509,0.424386052,1.18715561,0.311413493,DB0021310070608_,1.166633689,-0.342762868,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,pantoprazole,DB00213
,734584,DB01137,10070608,45,7727,40,5553,0.377669491,0.808498629,0.515487487,1.272115569,0.547698901,DB0113710070608_,0.602029595,-0.212576296,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,levofloxacin,DB01137
,734670,DB00678,10065154,145,15454,65,10659,0.003765849,1.538590001,1.139405251,2.096751957,0.016245746,DB0067810065154_,4.119924161,0.430866413,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,losartan,DB00678
,734710,DB01076,10053156,44,25703,17,25566,0.000727435,2.574545303,1.441021757,4.807430773,0.00422462,DB0107610053156_,5.466825912,0.945672937,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,atorvastatin,DB01076
,735049,DB00586,10042209,54,7055,12,2793,0.074475985,1.781425295,0.939444928,3.664442735,0.168955358,DB0058610042209_,1.778120753,0.577413771,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,diclofenac,DB00586
,735454,DB00688,10042674,37,6453,14,5364,0.010804725,2.196668403,1.15843184,4.403662026,0.037874534,DB0068810042674_,3.273476327,0.78694185,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,735551,DB04951,10010774,37,1845,46,3011,0.254190011,1.312578661,0.824417204,2.077367115,0.414799592,DB0495110010774_,0.879959786,0.271993646,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,pirfenidone,DB04951
,735722,DB00115,10076308,111,18314,43,10429,0.03527942,1.469969868,1.024142036,2.143815411,0.096006889,DB0011510076308_,2.343335334,0.385241903,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,735724,DB00213,10076308,70,18825,70,13351,0.047764384,0.709236216,0.501465713,1.003071176,0.120898101,DB0021310076308_,2.112807233,-0.343566641,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,735725,DB00264,10076308,164,29443,100,24792,0.011061721,1.380924765,1.069719191,1.79002333,0.038569655,DB0026410076308_,3.255289458,0.322753394,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,736360,DB01238,10073085,51,5199,34,3468,1,1.000590844,0.634330429,1.59626132,1,DB0123810073085_,0,0.00059067,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole,DB01238
,736577,DB00575,10027091,42,5202,8,3821,0.000131822,3.855755452,1.785558053,9.517788956,0.001009306,DB0057510027091_,6.898491858,1.349566955,female,10027091,Medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,clonidine,DB00575
,737042,DB00915,10022437,46,1409,34,1017,0.908958645,0.976537919,0.608470373,1.581093099,0.95913476,DB0091510022437_,0.041723693,-0.023741698,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,amantadine,DB00915
,737093,DB00915,10028813,56,1399,23,1028,0.020258211,1.788704177,1.074766829,3.067271652,0.062425213,DB0091510028813_,2.77378603,0.581491434,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,amantadine,DB00915
,737334,DB01026,10037153,63,1047,28,1040,0.0003707,2.234179131,1.397230737,3.653342391,0.00240591,DB0102610037153_,6.029827133,0.803873881,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,ketoconazole,DB01026
,737664,DB08895,10061520,48,28066,10,6636,0.867379805,1.134920412,0.566599841,2.517202526,0.940459036,DB0889510061520_,0.061387187,0.126562527,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,737719,DB00295,10076308,72,14591,49,9553,0.852428504,0.962010459,0.659347704,1.414032052,0.927730502,DB0029510076308_,0.075013996,-0.038729957,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,737899,DB09343,10028813,247,1272,223,1660,0.000215737,1.44529988,1.183396828,1.76590715,0.001535932,DB0934310028813_,6.47861818,0.368316829,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,tipiracil,DB09343
,737900,DB09343,10047700,126,1393,96,1787,0.000204608,1.683437941,1.268267227,2.240237728,0.001468429,DB0934310047700_,6.523562021,0.520838096,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,tipiracil,DB09343
,738758,DB00422,10062355,31,3404,22,2927,0.580475349,1.211598975,0.677580606,2.201529424,0.728979664,DB0042210062355_,0.316109443,0.191940954,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,methylphenidate,DB00422
,738958,DB01065,10049848,35,4296,21,3030,0.588783031,1.175462639,0.663981116,2.129668964,0.735593991,DB0106510049848_,0.307076955,0.161661805,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,melatonin,DB01065
,739112,DB00374,10020765,36,17680,17,5707,0.20111311,0.683576441,0.373832117,1.298798293,0.350329054,DB0037410020765_,1.048882413,-0.380416791,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,treprostinil,DB00374
,739138,DB09073,10003988,526,19734,10,780,0.015382937,2.078998472,1.115413789,4.378755931,0.05028798,DB0907310003988_,2.989989197,0.731886274,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,palbociclib,DB09073
,739195,DB00682,10023676,22,19437,31,16333,0.07233587,0.596361395,0.328843934,1.064170237,0.165349017,DB0068210023676_,1.799696783,-0.516908429,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,warfarin,DB00682
,739492,DB09035,10019717,35,4691,68,6622,0.132459003,0.726599306,0.468106597,1.110098439,0.25918893,DB0903510019717_,1.350198023,-0.319380114,NA,10019717,Hepatitis,10019805,Hepatobiliary disorders,Hepat,nivolumab,DB09035
,740053,DB00043,10022086,93,6320,36,2264,0.687943677,0.92542369,0.621546636,1.404543255,0.811861876,DB0004310022086_,0.208425057,-0.077503603,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,omalizumab,DB00043
,740236,DB06273,10016825,47,5048,9,1401,0.414468388,1.449262822,0.699948242,3.372005979,0.583675413,DB0627310016825_,0.53841025,0.371055028,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,tocilizumab,DB06273
,740442,DB00904,10019273,53,23016,55,14401,0.009783894,0.602973539,0.405329119,0.896312081,0.034979552,DB0090410019273_,3.35299163,-0.505881965,NA,10019273,Heart disease congenital,10010331,"Congenital, familial and genetic disorders",Cong,ondansetron,DB00904
,740492,DB09107,10008479,54,1161,38,965,0.456026132,1.181061969,0.758315116,1.855523543,0.623389239,DB0910710008479_,0.472584173,0.166414008,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,methoxy polyethylene glycol-epoetin beta,DB09107
,740709,DB00959,10011831,38,8040,28,4974,0.52598936,0.839623207,0.501199509,1.422329829,0.68391236,DB0095910011831_,0.379925498,-0.174802051,NA,10011831,Cytomegalovirus infection,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,740974,DB01610,10033661,20,921,30,1188,0.666430272,0.860000601,0.459684154,1.576759575,0.797174829,DB0161010033661_,0.226681265,-0.150822191,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,valganciclovir,DB01610
,741700,DB01377,10028411,40,3756,19,2651,0.184034356,1.485814691,0.838455567,2.722631569,0.328992625,DB0137710028411_,1.111719946,0.395963235,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,magnesium oxide,DB01377
,741716,DB08895,10051118,115,27999,65,6581,9.58900347793371e-08,0.415860273,0.303787526,0.573415754,1.7400549286675e-06,DB0889510051118_,13.26159388,-0.877405958,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,741852,DB13867,10037153,102,4448,28,2526,0.000421962,2.068573237,1.345981063,3.27443431,0.002677108,DB1386710037153_,5.923017988,0.726859112,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone,DB13867
,742075,DB13867,10046735,43,4507,20,2534,0.513036128,1.208739872,0.694077254,2.174158326,0.673105244,DB1386710046735_,0.395853581,0.189578389,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,fluticasone,DB13867
,742532,DB06262,10024264,21,3779,32,4282,0.334526839,0.74362775,0.406785319,1.332595011,0.503668115,DB0626210024264_,0.685837729,-0.296214706,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,742997,DB00999,10028245,61,21369,13,12226,0.000604915,2.684566853,1.45840406,5.328120412,0.003623148,DB0099910028245_,5.620411946,0.987519394,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,hydrochlorothiazide,DB00999
,744328,DB09045,10003549,31,2318,22,1702,1,1.03462541,0.577760483,1.882610677,1,DB0904510003549_,0,0.034039438,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,dulaglutide,DB09045
,744356,DB05676,10028997,72,47057,42,25287,0.694548836,0.921207582,0.620914388,1.382267238,0.816129157,DB0567610028997_,0.203182656,-0.082069881,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,apremilast,DB05676
,744642,DB06791,10012735,116,663,89,449,0.439681627,0.882761551,0.646468373,1.208242051,0.608008816,DB0679110012735_,0.497565897,-0.124700159,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,lanreotide,DB06791
,744648,DB06791,10025482,38,741,16,522,0.091461473,1.672454763,0.899300495,3.248814977,0.197605196,DB0679110025482_,1.621484197,0.514292465,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,lanreotide,DB06791
,744698,DB09035,10042128,23,4703,30,6660,0.781168393,1.085681337,0.601440048,1.935813765,0.880828655,DB0903510042128_,0.126892162,0.08220775,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,nivolumab,DB09035
,744737,DB08931,10022004,68,6509,22,2424,0.634457157,1.15105636,0.700874705,1.960131581,0.772713667,DB0893110022004_,0.257846716,0.140680095,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,744741,DB08931,10038687,37,6540,18,2428,0.361932802,0.763154539,0.422667915,1.426836001,0.531668232,DB0893110038687_,0.631735608,-0.270294727,NA,10038687,Respiratory distress,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,745119,DB00704,10054112,64,4292,62,5132,0.243267235,1.234252124,0.854512382,1.783792362,0.401607433,DB0070410054112_,0.912280202,0.210465219,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,naltrexone,DB00704
,745139,DB00619,10065154,51,2848,41,2453,0.75317956,1.071390622,0.693593793,1.663896847,0.861090197,DB0061910065154_,0.149556021,0.068957451,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,imatinib,DB00619
,745401,DB00956,10076308,64,5750,33,3434,0.528125629,1.158252893,0.747834659,1.824301245,0.68557089,DB0095610076308_,0.377503372,0.146912743,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocodone,DB00956
,745476,DB06605,10064373,31,14042,45,12988,0.065181886,0.637196181,0.38954497,1.030061311,0.152748707,DB0660510064373_,1.878961149,-0.450677694,NA,10064373,Labelled drug-drug interaction medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,745610,DB09035,10010774,47,4679,56,6634,0.421632446,1.18993568,0.788435251,1.789018541,0.590710169,DB0903510010774_,0.526429789,0.173899255,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,nivolumab,DB09035
,745611,DB09035,10054112,41,4685,42,6648,0.146619318,1.385148456,0.876949247,2.186473069,0.279206606,DB0903510054112_,1.275803248,0.325807322,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,nivolumab,DB09035
,745736,DB00582,10013722,24,1106,47,1527,0.181111403,0.705102092,0.409754153,1.184741347,0.325222522,DB0058210013722_,1.123245648,-0.349412676,NA,10013722,Drug level increased,10022891,Investigations,Inv,voriconazole,DB00582
,746234,DB00864,10020141,19,6850,44,8348,0.021661669,0.526278243,0.289901496,0.921325374,0.065865808,DB0086410020141_,2.720135825,-0.641925228,NA,10020141,Histoplasmosis,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,746272,DB01413,10070863,35,1185,46,1613,0.909433661,1.035687838,0.643282628,1.654621931,0.959305888,DB0141310070863_,0.041545289,0.035065783,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,cefepime,DB01413
,746601,DB09035,10039906,37,4689,49,6641,0.826198768,1.06943931,0.677277811,1.675840889,0.908265772,DB0903510039906_,0.096218242,0.067134502,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,nivolumab,DB09035
,746685,DB01069,10076308,52,6648,10,2385,0.081392991,1.865484557,0.935912108,4.123657049,0.180702515,DB0106910076308_,1.710903161,0.623520835,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,promethazine,DB01069
,746750,DB00864,10020144,33,6836,26,8366,0.114930185,1.553238268,0.899983176,2.707073299,0.233525439,DB0086410020144_,1.454464263,0.440341957,NA,10020144,Histoplasmosis disseminated,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,746753,DB01190,10028810,51,4883,9,2276,0.004869621,2.640984654,1.284900742,6.113005346,0.020032552,DB0119010028810_,3.910396712,0.971151823,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,clindamycin,DB01190
,747505,DB09029,10001760,164,11180,16,7254,7.01143170177327e-20,6.651431333,3.970171628,11.92001642,7.12941904375669e-18,DB0902910001760_,39.48230192,1.89483207,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,747554,DB09029,10011906,44,11300,85,7185,8.90826713732308e-10,0.329160808,0.223070981,0.479754007,2.50030754623104e-08,DB0902910011906_,17.504267,-1.111208869,male,10011906,Death,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,747720,DB09029,10015150,103,11241,80,7190,0.196323837,0.823530086,0.608009873,1.118847342,0.344578412,DB0902910015150_,1.065433602,-0.194155196,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,747756,DB09029,10006451,126,11218,52,7218,0.006798158,1.559044444,1.118487031,2.20026894,0.026191219,DB0902910006451_,3.642331061,0.444073098,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,secukinumab,DB09029
,747851,DB09073,10010774,748,19512,16,774,0.011393792,1.85450037,1.126939231,3.278455515,0.039511515,DB0907310010774_,3.23116312,0.617615317,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,palbociclib,DB09073
,748104,DB09078,10037844,32,761,56,1000,0.225528507,0.751006323,0.465623539,1.193264899,0.38030581,DB0907810037844_,0.966779588,-0.286341208,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,lenvatinib,DB09078
,748177,DB00820,10067973,36,11879,21,5795,0.572079417,0.83631173,0.474725199,1.509167414,0.722122,DB0082010067973_,0.325561179,-0.178753853,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,tadalafil,DB00820
,748299,DB01137,10064848,79,7693,44,5549,0.198453663,1.295045219,0.883135191,1.92066375,0.347236114,DB0113710064848_,1.057750285,0.258545613,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,levofloxacin,DB01137
,748373,DB00524,10016322,40,1537,17,1327,0.015199876,2.03094498,1.119403058,3.839718339,0.049835194,DB0052410016322_,2.999033835,0.708501192,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,metolazone,DB00524
,748532,DB00904,10014062,56,23013,20,14436,0.033076841,1.756406452,1.037165786,3.091737549,0.091451012,DB0090410014062_,2.391951838,0.563269933,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,ondansetron,DB00904
,748968,DB09071,10022437,120,864,83,699,0.329036889,1.169574911,0.860654927,1.595113519,0.497640014,DB0907110022437_,0.697878326,0.156640359,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,tasimelteon,DB09071
,749060,DB08932,10044055,39,19404,18,6579,0.286597838,0.734626075,0.410026283,1.365342807,0.451367674,DB0893210044055_,0.795473029,-0.308393651,NA,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,749182,DB00335,10064848,61,8405,26,5439,0.078348004,1.518186772,0.943446262,2.506915798,0.175617388,DB0033510064848_,1.739447584,0.417516709,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,atenolol,DB00335
,750508,DB00343,10038669,41,8695,14,5081,0.09251756,1.711274318,0.912778186,3.402366537,0.199248183,DB0034310038669_,1.613204082,0.537238308,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diltiazem,DB00343
,751550,DB00476,10048592,46,17211,10,6167,0.172434351,1.648311084,0.819787512,3.665381819,0.314054664,DB0047610048592_,1.158188219,0.499751178,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,duloxetine,DB00476
,752324,DB01611,10007636,47,11866,12,2349,0.480723865,0.77536107,0.404221873,1.608313468,0.645477182,DB0161110007636_,0.437765419,-0.254426461,NA,10007636,Cardiomyopathy,10007541,Cardiac disorders,Card,hydroxychloroquine,DB01611
,752748,DB01073,10010305,25,1040,46,1604,0.538949297,0.83828419,0.490294137,1.402969942,0.694827012,DB0107310010305_,0.364092368,-0.176398107,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,fludarabine,DB01073
,752792,DB01024,10033371,35,2176,15,2105,0.009731036,2.256648314,1.196848121,4.461452829,0.034826098,DB0102410033371_,3.357388217,0.813880666,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,mycophenolic acid,DB01024
,752961,DB14500,10028836,49,7760,15,4058,0.08506302,1.708194332,0.940700841,3.283939853,0.186872546,DB1450010028836_,1.677328464,0.535436866,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,potassium,DB14500
,753199,DB14512,10054112,42,4802,25,2387,0.515080931,0.835136153,0.495943139,1.433514339,0.674937176,DB1451210054112_,0.393135666,-0.18016051,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,mometasone furoate,DB14512
,753416,DB00863,10065154,61,10612,30,5810,0.661827428,1.113242731,0.706980638,1.787764971,0.79383654,DB0086310065154_,0.230877708,0.107277135,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,ranitidine,DB00863
,753418,DB00927,10065154,46,7451,34,4982,0.649302654,0.904632565,0.567273288,1.455526827,0.784181229,DB0092710065154_,0.243115126,-0.100226423,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,famotidine,DB00927
,753421,DB11089,10065154,52,10123,19,8388,0.001735724,2.267624152,1.317094141,4.0646565,0.008649828,DB1108910065154_,4.750215879,0.818732654,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,docusate,DB11089
,753726,DB08931,10020751,64,6513,13,2433,0.052367203,1.839003919,1.000593854,3.6465385,0.12946867,DB0893110020751_,2.044316359,0.609224077,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,riociguat,DB08931
,754006,DB01306,10028411,37,4171,28,3838,0.456939795,1.215899084,0.722648705,2.067012217,0.624287256,DB0130610028411_,0.47114467,0.19548379,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,insulin aspart,DB01306
,754179,DB09343,10002034,31,1488,38,1845,1,1.011511456,0.605381322,1.678508348,1,DB0934310002034_,0,0.011445703,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,tipiracil,DB09343
,754181,DB09343,10012174,30,1489,21,1862,0.04663576,1.786099024,0.984541446,3.297029307,0.118769592,DB0934310012174_,2.130569863,0.580033925,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,tipiracil,DB09343
,754266,DB00211,10044565,33,1403,29,1602,0.368270332,1.299215999,0.760546719,2.230376961,0.538001149,DB0021110044565_,0.619894584,0.261761005,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,midodrine,DB00211
,754544,DB00297,10061623,40,1632,13,866,0.144501965,1.632441752,0.849787356,3.345235372,0.276325645,DB0029710061623_,1.286175236,0.490076901,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,bupivacaine,DB00297
,754689,DB00814,10037162,127,8160,46,3369,0.500477684,1.13985664,0.805442942,1.637955571,0.662039502,DB0081410037162_,0.412430054,0.1309025,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,meloxicam,DB00814
,755039,DB08895,10023469,49,28065,17,6629,0.207994873,0.680825881,0.3849846,1.261822953,0.358821189,DB0889510023469_,1.024931095,-0.384448687,NA,10023469,Knee arthroplasty,10042613,Surgical and medical procedures,Surg,tofacitinib,DB08895
,755044,DB08895,10048706,346,27768,90,6556,0.425527483,0.907655058,0.716615949,1.159614699,0.594235086,DB0889510048706_,0.520480271,-0.096890865,NA,10048706,Joint range of motion decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,755053,DB08895,10061156,50,28064,12,6634,1,0.984950757,0.516816872,2.033192152,1,DB0889510061156_,0,-0.015163632,NA,10061156,Finger deformity,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,755061,DB01610,10058854,45,896,80,1138,0.094053462,0.714535163,0.479288951,1.054163987,0.20184481,DB0161010058854_,1.600256143,-0.336123069,NA,10058854,Cytomegalovirus viraemia,10021881,Infections and infestations,Infec,valganciclovir,DB01610
,755106,DB04951,10065154,44,1838,58,2999,0.303712831,1.237745325,0.813259358,1.872252775,0.470271377,DB0495110065154_,0.754445353,0.213291438,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,pirfenidone,DB04951
,755147,DB01222,10064848,34,9240,16,5389,0.557884481,1.239371465,0.664927063,2.406900264,0.710912571,DB0122210064848_,0.341205823,0.214604368,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,budesonide,DB01222
,755326,DB00688,10054112,62,6428,42,5336,0.324072753,1.225390927,0.813598011,1.861831386,0.492498399,DB0068810054112_,0.708264069,0.203259917,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,mycophenolate mofetil,DB00688
,755666,DB00959,10042458,45,8033,19,4983,0.196862209,1.469128423,0.840943546,2.662790489,0.345221373,DB0095910042458_,1.063569407,0.384669315,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,methylprednisolone,DB00959
,755824,DB11581,10035664,64,1689,138,2622,0.032399482,0.720003548,0.523331176,0.981929935,0.089961484,DB1158110035664_,2.408373651,-0.328499139,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,venetoclax,DB11581
,755825,DB00586,10051118,37,7072,13,2792,0.874991114,1.123635726,0.582663709,2.307336254,0.946077394,DB0058610051118_,0.055430902,0.116569612,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,756636,DB06262,10033371,46,3754,23,4291,0.00098486,2.285879858,1.354417094,3.95910817,0.00543503,DB0626210033371_,5.2148903,0.826751008,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,757252,DB00003,10008469,41,2957,29,2564,0.469628896,1.225847565,0.741126824,2.051694486,0.635938155,DB0000310008469_,0.452653961,0.203632494,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,dornase alfa,DB00003
,757253,DB08820,10008469,102,4299,63,3482,0.096907189,1.311311416,0.945362569,1.830889176,0.206117936,DB0882010008469_,1.579306767,0.271027717,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,ivacaftor,DB08820
,757279,DB00003,10028813,61,2937,29,2564,0.007450749,1.836112695,1.15769279,2.973442798,0.028144418,DB0000310028813_,3.570406249,0.607650671,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dornase alfa,DB00003
,757290,DB08820,10038647,36,4365,28,3517,1,1.035935911,0.613344987,1.7662891,1,DB0882010038647_,0,0.03530528,NA,10038647,Respiration abnormal,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ivacaftor,DB08820
,757549,DB00051,10074903,56,25675,21,11399,0.539549228,1.183910807,0.705229162,2.059524013,0.695339776,DB0005110074903_,0.363354666,0.168823202,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,757614,DB00688,10058080,36,6454,44,5334,0.090874576,0.676228073,0.422236162,1.076663444,0.196628105,DB0068810058080_,1.626441126,-0.391224874,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,757621,DB08820,10058080,32,4369,32,3513,0.449015121,0.804100304,0.475927021,1.358597378,0.616665575,DB0882010058080_,0.483428419,-0.218031261,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,ivacaftor,DB08820
,757697,DB08895,10023215,77,28037,28,6618,0.061097539,0.649134468,0.415892998,1.040258699,0.145472966,DB0889510023215_,1.92776501,-0.432115392,NA,10023215,Joint effusion,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,757880,DB00230,10066901,52,19622,23,8628,1,0.994128319,0.597273918,1.702982896,1,DB0023010066901_,0,-0.005888987,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,757891,DB08932,10031123,57,19386,15,6582,0.418559873,1.290164231,0.720122314,2.455404779,0.587595602,DB0893210031123_,0.531716319,0.254769521,NA,10031123,Orthopnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,757896,DB08932,10053405,65,19378,17,6580,0.375401307,1.298293072,0.751422057,2.364601279,0.545282016,DB0893210053405_,0.606452158,0.26105038,NA,10053405,Brain natriuretic peptide increased,10022891,Investigations,Inv,macitentan,DB08932
,757926,DB09029,10009900,41,11303,39,7231,0.08474924,0.672583279,0.422707733,1.071674713,0.186334904,DB0902910009900_,1.680209663,-0.396629341,NA,10009900,Colitis ulcerative,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,757959,DB08895,10023547,45,28069,13,6633,0.505114519,0.81800313,0.433344623,1.653847996,0.666037066,DB0889510023547_,0.406409956,-0.200889116,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,tofacitinib,DB08895
,758005,DB09078,10000081,39,754,31,1025,0.03565204,1.70969016,1.028979081,2.862505068,0.096779292,DB0907810000081_,2.335322238,0.536312161,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,lenvatinib,DB09078
,758402,DB01254,10076309,30,3437,23,3125,0.58243956,1.185911908,0.664466077,2.142838048,0.730598793,DB0125410076309_,0.313890816,0.170512022,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,dasatinib,DB01254
,758605,DB00853,10040047,13,1808,43,2223,0.001052188,0.37181133,0.182856074,0.707055377,0.005748653,DB0085310040047_,5.158789699,-0.989368731,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,temozolomide,DB00853
,758708,DB01104,10060795,38,15425,13,7273,0.368966532,1.378268175,0.717622278,2.821609272,0.538596873,DB0110410060795_,0.618787905,0.320827765,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,sertraline,DB01104
,759230,DB09079,10021240,15,642,44,833,0.006837461,0.442555398,0.22664027,0.819385224,0.02631564,DB0907910021240_,3.637591839,-0.815189629,NA,10021240,Idiopathic pulmonary fibrosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nintedanib,DB09079
,759413,DB04951,10037844,102,1780,197,2860,0.157590538,0.831963705,0.643644038,1.070216928,0.294273148,DB0495110037844_,1.223246869,-0.183966463,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,pirfenidone,DB04951
,759628,DB00704,10037087,37,4319,29,5165,0.106355619,1.525690642,0.911379,2.57681145,0.220698647,DB0070410037087_,1.510957097,0.422447188,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,naltrexone,DB00704
,761246,DB00321,10076308,57,7390,31,2819,0.119924959,0.701422884,0.444204783,1.126552002,0.241272678,DB0032110076308_,1.42182754,-0.354644316,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,amitriptyline,DB00321
,761750,DB09035,10003246,35,4691,44,6646,0.647007835,1.126950531,0.700584526,1.800595896,0.782313016,DB0903510003246_,0.245500343,0.11951534,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,nivolumab,DB09035
,761818,DB09035,10005364,32,4694,49,6641,0.821060985,0.923933019,0.571703089,1.474501197,0.904700649,DB0903510005364_,0.100151165,-0.0791157,NA,10005364,Blood bilirubin increased,10022891,Investigations,Inv,nivolumab,DB09035
,762452,DB00563,10049463,32,46614,45,15303,3.35706988534257e-10,0.233472601,0.143513929,0.375704671,1.01309508537577e-08,DB0056310049463_,18.40767066,-1.454690548,male,10049463,Drug clearance decreased,10022891,Investigations,Inv,methotrexate,DB00563
,762477,DB05676,10061218,65,47064,29,25300,0.449447318,1.204856819,0.766396291,1.936888806,0.617065696,DB0567610061218_,0.482779784,0.186360737,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,762706,DB00695,10051118,33,28016,19,20509,0.48298842,1.271441384,0.701864677,2.367310728,0.647177153,DB0069510051118_,0.435135215,0.240151205,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,762707,DB00264,10061920,20,29587,34,24858,0.013292246,0.49422742,0.269494845,0.883800632,0.044655763,DB0026410061920_,3.108771898,-0.704759503,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,763099,DB06605,10064911,125,13948,54,12979,1.24152427958632e-06,2.153846136,1.551908722,3.024378171,1.73628442079949e-05,DB0660510064911_,10.96117803,0.767255145,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,763159,DB00199,10046735,57,2653,18,682,0.469515588,0.814099068,0.46848488,1.479959399,0.635850236,DB0019910046735_,0.452792222,-0.205673216,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,erythromycin,DB00199
,763310,DB00704,10016322,225,4131,346,4848,0.00209089,0.763179705,0.639008415,0.910092747,0.010093284,DB0070410016322_,4.595885047,-0.270261751,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,763698,DB00421,10036018,39,8864,13,5239,0.083787744,1.77306009,0.925459483,3.623553667,0.184730821,DB0042110036018_,1.688855535,0.572706918,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,spironolactone,DB00421
,764256,DB09037,10008531,25,2501,32,2803,0.689700852,0.875609225,0.495992968,1.529609782,0.812888491,DB0903710008531_,0.207161336,-0.132835378,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,pembrolizumab,DB09037
,764683,DB00264,10007556,51,29556,33,24859,0.273249128,1.299845105,0.822502661,2.079878865,0.436219454,DB0026410007556_,0.829609826,0.262245107,NA,10007556,Cardiac failure acute,10007541,Cardiac disorders,Card,metoprolol,DB00264
,764954,DB00497,10025256,37,19230,33,16342,0.904603658,0.952804636,0.579418864,1.573000517,0.957573483,DB0049710025256_,0.043352816,-0.048345395,NA,10025256,Lymphocyte count decreased,10022891,Investigations,Inv,oxycodone,DB00497
,765247,DB00190,10048959,103,3194,133,4541,0.502362011,1.101023025,0.839405722,1.4409281,0.663630379,DB0019010048959_,0.410029943,0.096239771,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,765745,DB06262,10008469,42,3758,13,4301,9.18650149652173e-06,3.697116787,1.943084462,7.518573619,0.000100842,DB0626210008469_,9.201951387,1.307553269,female,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,765749,DB06605,10076309,62,14011,57,12976,1,1.007368969,0.691025481,1.470840142,1,DB0660510076309_,0,0.007341951,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,766260,DB09078,10005750,66,727,110,946,0.149394087,0.780846622,0.557711088,1.086616102,0.283136749,DB0907810005750_,1.261825284,-0.247376535,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,lenvatinib,DB09078
,766429,DB00476,10054112,103,17154,26,6151,0.132171092,1.420452985,0.915504448,2.278636506,0.25890413,DB0047610054112_,1.351297441,0.350975824,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,duloxetine,DB00476
,766463,DB09029,10028810,278,11066,147,7123,0.056160207,1.217270129,0.990883659,1.500417654,0.136379438,DB0902910028810_,1.992314295,0.196610753,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,secukinumab,DB09029
,766996,DB09045,10064355,63,2286,36,1688,0.257409666,1.292132978,0.840258679,2.013886196,0.418313585,DB0904510064355_,0.871523924,0.256294324,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,dulaglutide,DB09045
,767440,DB00704,10016173,46,4310,45,5149,0.343751977,1.221181697,0.790156144,1.888355212,0.5130175,DB0070410016173_,0.667445322,0.199818994,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,naltrexone,DB00704
,767749,DB00704,10020937,44,4312,33,5161,0.050250787,1.595757939,0.991223306,2.591896327,0.125461753,DB0070410020937_,2.075754322,0.46734882,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,naltrexone,DB00704
,767753,DB01065,10020937,60,4271,25,3026,0.026492354,1.700278207,1.047290616,2.836933698,0.076838788,DB0106510020937_,2.566045712,0.530791889,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,melatonin,DB01065
,767772,DB00704,10022437,153,4203,274,4920,3.51128312105758e-05,0.653682529,0.530480158,0.803141339,0.000325667,DB0070410022437_,8.02963464,-0.425133475,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,767892,DB00704,10027951,21,4335,31,5163,0.487258168,0.80682744,0.439956397,1.452141847,0.651131245,DB0070410027951_,0.429044052,-0.214645462,NA,10027951,Mood swings,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,767935,DB00704,10028334,65,4291,91,5103,0.331711438,0.849467189,0.606524004,1.184031548,0.500537233,DB0070410028334_,0.692073291,-0.163145963,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,naltrexone,DB00704
,769247,DB06605,10062355,118,13955,85,12948,0.078179153,1.288045054,0.965330599,1.724729386,0.175306179,DB0660510062355_,1.74122124,0.253125607,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,769470,DB00836,10000381,54,5481,55,4020,0.097368468,0.720142749,0.484273849,1.070465339,0.206921838,DB0083610000381_,1.575414153,-0.328305824,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,loperamide,DB00836
,770164,DB09331,10013968,116,1969,129,2300,0.741930958,1.050405165,0.804199448,1.370697289,0.852093841,DB0933110013968_,0.160058616,0.049175961,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,daratumumab,DB09331
,770724,DB00028,10001760,54,13404,14,5601,0.141564005,1.611728392,0.882016494,3.144670412,0.271983764,DB0002810001760_,1.302012907,0.477307139,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,human immunoglobulin g,DB00028
,772348,DB00571,10022000,47,5076,15,2594,0.137267612,1.601144977,0.877655176,3.089087242,0.265935446,DB0057110022000_,1.324501682,0.470718984,NA,10022000,Influenza,10021881,Infections and infestations,Infec,propranolol,DB00571
,772399,DB00915,10025482,35,1420,16,1035,0.151264772,1.594125693,0.853978076,3.102181073,0.285621532,DB0091510025482_,1.253087658,0.466325431,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,amantadine,DB00915
,773214,DB00704,10035664,31,4325,26,5168,0.185414704,1.424637632,0.817182396,2.502193533,0.330695538,DB0070410035664_,1.106557152,0.353917488,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,naltrexone,DB00704
,775289,DB00343,10034474,39,8697,24,5071,0.895977366,0.947500374,0.554906506,1.649142792,0.956298578,DB0034310034474_,0.044685095,-0.053927947,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,diltiazem,DB00343
,775525,DB01276,10069868,51,1966,40,1471,0.830815152,0.953963463,0.614564117,1.489882974,0.911439174,DB0127610069868_,0.092730419,-0.047129907,NA,10069868,Device issue,10077536,Product issues,Prod,exenatide,DB01276
,775968,DB00203,10051118,14,13864,36,8902,3.24707975309212e-06,0.249719744,0.124341119,0.474757528,4.05846368568837e-05,DB0020310051118_,10.11212097,-1.387416013,male,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,777223,DB08931,10039101,86,6491,21,2425,0.080975872,1.529960222,0.938296493,2.602457454,0.18000345,DB0893110039101_,1.714779261,0.425241736,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,778866,DB08895,10036790,92,28022,23,6623,0.812225474,0.94539375,0.592899218,1.566159363,0.89905753,DB0889510036790_,0.106408254,-0.056153772,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tofacitinib,DB08895
,780500,DB00019,10064684,67,18945,31,9498,0.748731195,1.083549212,0.697386675,1.717698702,0.857421664,DB0001910064684_,0.153825458,0.08024196,NA,10064684,Device dislocation,10077536,Product issues,Prod,pegfilgrastim,DB00019
,781202,DB00497,10063746,45,19222,37,16338,0.912052081,1.033743898,0.653894009,1.643337559,0.960583762,DB0049710063746_,0.040214094,0.033187065,NA,10063746,Accidental death,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,782046,DB00421,10003662,31,8872,20,5232,0.772571386,0.914074075,0.504084379,1.693905658,0.87552983,DB0042110003662_,0.132926056,-0.089843666,NA,10003662,Atrial flutter,10007541,Cardiac disorders,Card,spironolactone,DB00421
,783026,DB09073,10028810,387,19873,7,783,0.032027989,2.178210037,1.042081871,5.472938427,0.08916546,DB0907310028810_,2.417261535,0.778503455,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,palbociclib,DB09073
,783816,DB09073,10012378,282,19978,8,782,0.438583925,1.379782814,0.68726589,3.238866141,0.606921239,DB0907310012378_,0.499356252,0.321926106,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,palbociclib,DB09073
,784086,DB00190,10061623,43,3254,46,4628,0.194502704,1.329428267,0.854256722,2.065464099,0.342385719,DB0019010061623_,1.071817343,0.284748975,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,785977,DB00321,10054112,44,7403,27,2823,0.0615043,0.621461367,0.375563394,1.045903287,0.146229526,DB0032110054112_,1.922577795,-0.475681531,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,amitriptyline,DB00321
,786858,DB00215,10076308,45,11058,19,5257,0.788805507,1.125939804,0.64463992,2.04054662,0.885573892,DB0021510076308_,0.121519379,0.118618068,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,787203,DB06605,10017412,40,14033,23,13010,0.076772339,1.612313973,0.941627651,2.822735946,0.172831231,DB0660510017412_,1.755439702,0.477670397,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,apixaban,DB06605
,787283,DB00497,10037162,34,19233,17,16358,0.090648502,1.701005344,0.923922858,3.247989522,0.196243947,DB0049710037162_,1.628396768,0.531219455,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,787938,DB01075,10001052,40,19908,28,11069,0.375809402,0.794317734,0.477692344,1.337700065,0.545603432,DB0107510001052_,0.605862882,-0.230271729,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diphenhydramine,DB01075
,788133,DB06262,10040047,19,3781,34,4280,0.128491115,0.632611437,0.340259527,1.143199363,0.253491121,DB0626210040047_,1.372426482,-0.457898889,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,droxidopa,DB06262
,788767,DB06674,10066901,160,4346,40,1450,0.113961067,1.334477611,0.933271624,1.94770176,0.232107755,DB0667410066901_,1.460553554,0.288539913,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,golimumab,DB06674
,789117,DB00541,10000846,21,3113,37,4260,0.42359223,0.776716897,0.431069837,1.365199435,0.592413831,DB0054110000846_,0.523549849,-0.252679349,NA,10000846,Acute lymphocytic leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,vincristine,DB00541
,789464,DB09292,10031127,22,4507,39,8223,0.894124404,1.02922265,0.580472337,1.781918775,0.955860142,DB0929210031127_,0.045143671,0.028803809,NA,10031127,Orthostatic hypotension,10047065,Vascular disorders,Vasc,sacubitril,DB09292
,789469,DB00490,10042772,42,4028,8,1568,0.07979982,2.043477591,0.944996991,5.05051668,0.178083489,DB0049010042772_,1.7255028,0.714653058,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,buspirone,DB00490
,792899,DB00333,10012373,22,3049,34,3118,0.140994713,0.661748544,0.367800144,1.167765801,0.271286584,DB0033310012373_,1.304579511,-0.412869638,NA,10012373,Depressed level of consciousness,10029205,Nervous system disorders,Nerv,methadone,DB00333
,794370,DB04861,10013700,41,1924,16,1371,0.042048332,1.825667802,0.997664426,3.500202763,0.109796236,DB0486110013700_,2.209129029,0.601945839,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,nebivolol,DB04861
,796082,DB06168,10033371,38,571,16,384,0.152312821,1.596494352,0.854918245,3.112703678,0.287194537,DB0616810033371_,1.247595462,0.467810196,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,canakinumab,DB06168
,796141,DB00193,10043882,52,19268,30,8672,0.283328597,0.780103633,0.488111165,1.267611171,0.447689177,DB0019310043882_,0.803656088,-0.248328505,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,tramadol,DB00193
,796452,DB05676,10067484,51,47078,22,25307,0.461456959,1.24609939,0.742083304,2.15820614,0.628726734,DB0567610067484_,0.464058562,0.220018185,NA,10067484,Adverse reaction,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,797378,DB00864,10014581,9,6860,41,8351,8.52195951744299e-05,0.267248046,0.114134009,0.558715438,0.000696107,DB0086410014581_,7.270007687,-1.31957804,male,10014581,Encephalitis,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,798160,DB00999,10027635,16,21414,34,12205,9.74556992504064e-06,0.268224667,0.138188716,0.499621312,0.000106225,DB0099910027635_,9.149948269,-1.315930338,male,10027635,Milk-alkali syndrome,10027433,Metabolism and nutrition disorders,Metab,hydrochlorothiazide,DB00999
,800072,DB04951,10033318,24,1858,34,3023,0.590080358,1.14844584,0.649375015,2.001655503,0.73674206,DB0495110033318_,0.305517435,0.138409585,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,pirfenidone,DB04951
,800501,DB00028,10022081,40,13418,13,5602,0.546104877,1.284569067,0.672440322,2.619821227,0.700742839,DB0002810022081_,0.355614307,0.250423306,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,800716,DB01068,10019075,30,13733,32,6808,0.002799422,0.464766112,0.272577279,0.790533991,0.012769252,DB0106810019075_,4.360715181,-0.766220985,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,clonazepam,DB01068
,800728,DB00190,10029412,37,3260,59,4615,0.603452382,0.887761473,0.570657532,1.365367284,0.747103097,DB0019010029412_,0.291552088,-0.119052184,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,801479,DB06273,10047942,46,5049,18,1392,0.222105566,0.704603965,0.399232282,1.295454136,0.376174799,DB0627310047942_,0.977701353,-0.350119386,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,tocilizumab,DB06273
,802802,DB06212,10054112,54,620,44,528,0.915968682,1.045135533,0.676569472,1.621734562,0.962395043,DB0621210054112_,0.038330265,0.044146574,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,tolvaptan,DB06212
,802856,DB09029,10033425,211,11133,120,7150,0.306498204,1.129284503,0.896458315,1.427867737,0.473500977,DB0902910033425_,0.747601302,0.121584249,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,secukinumab,DB09029
,805055,DB01101,10067482,44,7545,35,3873,0.056737387,0.645322851,0.403847671,1.038247765,0.137336974,DB0110110067482_,1.985317706,-0.438004543,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,capecitabine,DB01101
,805136,DB00668,10064774,70,10021,31,4272,0.828355185,0.962624734,0.621190691,1.522876513,0.909762627,DB0066810064774_,0.094571563,-0.038091628,NA,10064774,Infusion site extravasation,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,806683,DB09029,10048959,157,11187,77,7193,0.05881519,1.310988995,0.990181246,1.748076792,0.141242295,DB0902910048959_,1.957278461,0.27078181,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,807343,DB09029,10037087,371,10973,217,7053,0.28323373,1.098925357,0.924347363,1.308881667,0.447578596,DB0902910037087_,0.803903123,0.094332754,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,807517,DB09027,10073071,14,5165,48,7104,0.001773467,0.401192535,0.204042285,0.740767772,0.00880952,DB0902710073071_,4.731922289,-0.913313829,NA,10073071,Hepatocellular carcinoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ledipasvir,DB09027
,807865,DB00635,10006445,38,33015,19,23775,0.226910773,1.440244083,0.8097106,2.645603331,0.38208518,DB0063510006445_,0.96211171,0.364812601,NA,10006445,Bronchiectasis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,prednisone,DB00635
,807921,DB00091,10054112,44,5466,20,2650,0.893908936,1.066584189,0.614103512,1.914321982,0.9558569,DB0009110054112_,0.045147063,0.064461195,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,cyclosporine,DB00091
,808667,DB09029,10021972,41,11303,28,7242,0.805592898,0.938193308,0.565755303,1.576874619,0.894819529,DB0902910021972_,0.111133225,-0.063799265,NA,10021972,Inflammatory bowel disease,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,808838,DB01224,10009895,32,8076,20,5897,0.673628487,1.168266734,0.647271939,2.15772389,0.802116686,DB0122410009895_,0.220501188,0.155521227,NA,10009895,Colitis ischaemic,10017947,Gastrointestinal disorders,Gastr,quetiapine,DB01224
,811500,DB00410,10017577,42,1563,8,1001,0.000634425,3.361002853,1.550471557,8.324174261,0.003775809,DB0041010017577_,5.57914056,1.212239397,female,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,mupirocin,DB00410
,820363,DB01590,10022437,58,4680,46,2821,0.185269086,0.760068033,0.505723296,1.148058391,0.330536749,DB0159010022437_,1.107037432,-0.274347333,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,everolimus,DB01590
,820365,DB11065,10022437,34,3152,26,2662,0.794806406,1.104352561,0.641557246,1.921802752,0.88886159,DB1106510022437_,0.117813747,0.099259246,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,pancrelipase amylase,DB11065
,820673,DB00433,10052015,30,7626,35,5985,0.132359474,0.672727765,0.398481072,1.129335919,0.259100263,DB0043310052015_,1.350540178,-0.39641454,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,prochlorperazine,DB00433
,823280,DB00472,10064848,45,10714,15,4297,0.66766435,1.203167717,0.65743981,2.326248466,0.798169392,DB0047210064848_,0.225434433,0.184957843,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,fluoxetine,DB00472
,824853,DB09140,10023232,44,3697,16,1782,0.405858681,1.325510888,0.730846549,2.523564631,0.575404285,DB0914010023232_,0.552682382,0.281797961,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,oxygen,DB09140
,825013,DB00169,10053505,49,38642,6,18169,0.000418315,3.839386367,1.64290153,10.9711145,0.002658145,DB0016910053505_,5.93012669,1.345312554,female,10053505,Infusion site swelling,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,825491,DB08895,10019708,46,28068,12,6634,0.738836126,0.906009963,0.471982173,1.880044387,0.849736707,DB0889510019708_,0.162828734,-0.098704977,NA,10019708,Hepatic steatosis,10019805,Hepatobiliary disorders,Hepat,tofacitinib,DB08895
,825710,DB00285,10076308,64,10887,24,3694,0.71228445,0.904805581,0.557126608,1.515165921,0.828901438,DB0028510076308_,0.187654024,-0.100035186,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,825965,DB08904,10052904,90,11520,21,3538,0.311264565,1.316187104,0.810104385,2.232475227,0.4787683,DB0890410052904_,0.736538514,0.274738999,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,certolizumab pegol,DB08904
,827497,DB01611,10042868,49,11864,9,2352,1,1.079364387,0.523765826,2.502653295,1,DB0161110042868_,0,0.076372337,NA,10042868,Synovitis,10028395,Musculoskeletal and connective tissue disorders,Musc,hydroxychloroquine,DB01611
,828196,DB08895,10062016,42,28072,8,6638,0.719223834,1.241423656,0.57541011,3.06292301,0.834225382,DB0889510062016_,0.181251671,0.21625883,NA,10062016,Immunosuppression,10021428,Immune system disorders,Immun,tofacitinib,DB08895
,828202,DB08932,10053459,61,19382,21,6576,1,0.985539028,0.591105504,1.705392444,1,DB0893210053459_,0,-0.014566551,NA,10053459,Secretion discharge,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,829137,DB08820,10002855,45,4356,21,3524,0.045845644,1.73345121,1.009191343,3.069760344,0.117183134,DB0882010002855_,2.144017319,0.55011434,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,ivacaftor,DB08820
,830523,DB00374,10076308,43,17673,11,5713,0.634006218,1.263638293,0.640263731,2.719080002,0.772397092,DB0037410076308_,0.258256494,0.233995094,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,830746,DB00864,10014387,27,6842,40,8352,0.462549772,0.823980469,0.485733501,1.377925635,0.629791284,DB0086410014387_,0.462366809,-0.193608452,NA,10014387,Electrocardiogram QT prolonged,10022891,Investigations,Inv,tacrolimus,DB00864
,832571,DB09073,10003658,49,20211,7,783,0.004784169,0.271239028,0.121671955,0.712055166,0.019745918,DB0907310003658_,3.92480849,-1.304754826,male,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,palbociclib,DB09073
,833067,DB00989,10069889,95,739,77,801,0.076923891,1.337040286,0.962621674,1.861617416,0.173052419,DB0098910069889_,1.75416073,0.290458429,NA,10069889,Product adhesion issue,10077536,Product issues,Prod,rivastigmine,DB00989
,833112,DB00190,10054112,35,3262,62,4612,0.301516205,0.798167263,0.51047811,1.230461016,0.467807068,DB0019010054112_,0.759699315,-0.2254371,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,carbidopa,DB00190
,833124,DB00788,10064848,73,9283,41,5020,0.844301781,0.962867505,0.646982881,1.450324348,0.92132734,DB0078810064848_,0.081939888,-0.037839462,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,naproxen,DB00788
,833133,DB08868,10022000,87,9115,26,2485,0.646619299,0.912247596,0.581356845,1.476837214,0.782032295,DB0886810022000_,0.245859241,-0.091843838,NA,10022000,Influenza,10021881,Infections and infestations,Infec,fingolimod,DB08868
,834295,DB09035,10037087,45,4681,71,6619,0.635907367,0.896189667,0.601596037,1.322958648,0.773708023,DB0903510037087_,0.256560708,-0.109603207,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,nivolumab,DB09035
,834532,DB05676,10054112,52,47077,43,25286,0.040466959,0.649519482,0.425172593,0.996902804,0.106592767,DB0567610054112_,2.238739621,-0.431522448,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,apremilast,DB05676
,834604,DB00482,10065154,64,8195,20,3051,0.540014996,1.191336073,0.710130824,2.082229388,0.695620828,DB0048210065154_,0.362950555,0.175075427,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,celecoxib,DB00482
,834928,DB09045,10022086,186,2163,106,1618,0.031465321,1.312502512,1.019104973,1.697214139,0.087934289,DB0904510022086_,2.431165463,0.27193563,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,dulaglutide,DB09045
,836181,DB00451,10013663,45,47226,11,15408,0.441046322,1.334683446,0.679470433,2.862422144,0.609222901,DB0045110013663_,0.495571067,0.288694145,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,levothyroxine,DB00451
,837078,DB09045,10012671,42,2307,27,1697,0.624720154,1.144181075,0.686049207,1.938064346,0.764450048,DB0904510012671_,0.268598595,0.134689163,NA,10012671,Diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,dulaglutide,DB09045
,837524,DB00635,10005619,34,33019,17,23777,0.256461402,1.440190752,0.782356889,2.749542921,0.417289789,DB0063510005619_,0.873974362,0.364775572,NA,10005619,Blood iron decreased,10022891,Investigations,Inv,prednisone,DB00635
,837904,DB08932,10040984,65,19378,25,6572,0.627157978,0.881802231,0.547702105,1.461298152,0.766630119,DB0893210040984_,0.265750838,-0.125787476,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,macitentan,DB08932
,838791,DB09072,10076308,122,6349,66,2469,0.040080842,0.718867209,0.526502712,0.988878393,0.105849491,DB0907210076308_,2.245737093,-0.330078626,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium oxybate,DB09072
,838803,DB00199,10013968,49,2661,13,687,0.874986463,0.973121916,0.516241068,1.966836259,0.946077394,DB0019910013968_,0.055430902,-0.027245906,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,erythromycin,DB00199
,839226,DB09073,10021789,170,20090,7,783,0.841385213,0.946504317,0.447415186,2.398086428,0.919060416,DB0907310021789_,0.084403418,-0.054979747,NA,10021789,Infection,10021881,Infections and infestations,Infec,palbociclib,DB09073
,839390,DB00541,10009802,15,3119,45,4252,0.008123391,0.454467287,0.234860778,0.832461368,0.030165055,DB0054110009802_,3.501071155,-0.788629343,NA,10009802,Coagulopathy,10005329,Blood and lymphatic system disorders,Blood,vincristine,DB00541
,839745,DB09035,10033371,62,4664,77,6613,0.43720433,1.141654707,0.801907405,1.619657864,0.605671448,DB0903510033371_,0.501417604,0.132478707,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,nivolumab,DB09035
,840420,DB00115,10048010,45,18380,12,10460,0.018378346,2.134061188,1.109623074,4.434094414,0.057797896,DB0011510048010_,2.850802901,0.758026825,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,841126,DB08931,10047461,44,6533,8,2438,0.060432444,2.052404038,0.953916703,5.054523911,0.144202592,DB0893110047461_,1.936536077,0.719011808,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,riociguat,DB08931
,841371,DB00190,10039906,32,3265,41,4633,0.720575708,1.107488105,0.673517362,1.806540932,0.835203726,DB0019010039906_,0.180079601,0.102094483,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,842024,DB06605,10029216,38,14035,12,13021,0.000580051,2.937536382,1.502083125,6.177414302,0.00349453,DB0660510029216_,5.65655646,1.077571265,female,10029216,Nervousness,10037175,Psychiatric disorders,Psych,apixaban,DB06605
,842545,DB06605,10074300,37,14036,24,13009,0.199662159,1.42884128,0.831769489,2.497981479,0.348665948,DB0660510074300_,1.053640985,0.356863822,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,apixaban,DB06605
,843261,DB09027,10028810,49,5130,48,7104,0.098332162,1.413581956,0.928181007,2.153892192,0.208364777,DB0902710028810_,1.568465001,0.346126877,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ledipasvir,DB09027
,845250,DB08906,10028810,58,2135,11,1147,0.00076373,2.831978716,1.464384666,6.008513689,0.004399923,DB0890610028810_,5.426168139,1.04097566,female,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,fluticasone furoate,DB08906
,846018,DB09035,10021015,55,4671,27,6663,4.24261293902909e-06,2.905487559,1.798586564,4.798540752,5.11216891652917e-05,DB0903510021015_,9.881301705,1.066601211,female,10021015,Hypokalaemia,10027433,Metabolism and nutrition disorders,Metab,nivolumab,DB09035
,846020,DB09035,10028372,46,4680,85,6605,0.153762279,0.763793801,0.520514895,1.108398648,0.289174079,DB0903510028372_,1.240726423,-0.26945742,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,nivolumab,DB09035
,846023,DB09035,10061428,58,4668,85,6605,0.864692597,0.965496784,0.67776038,1.367117991,0.938004886,DB0903510061428_,0.064000121,-0.035112508,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,nivolumab,DB09035
,846040,DB00457,10053762,36,643,18,493,0.16068363,1.532903554,0.836303535,2.904103258,0.29847491,DB0045710053762_,1.209069402,0.427163685,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,prazosin,DB00457
,846554,DB08904,10069327,43,11567,19,3540,0.17872089,0.692642439,0.394484396,1.260244245,0.322266487,DB0890410069327_,1.132376475,-0.367241374,NA,10069327,Product quality issue,10077536,Product issues,Prod,certolizumab pegol,DB08904
,847128,DB06228,10022086,54,15858,10,16066,9.87863883417525e-09,5.470412334,2.756874773,12.05350181,2.22692986068865e-07,DB0622810022086_,15.31747176,1.699353995,female,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,rivaroxaban,DB06228
,847214,DB09029,10046306,166,11178,87,7183,0.135635571,1.226076447,0.938640363,1.610946785,0.263628572,DB0902910046306_,1.333214091,0.203819191,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,secukinumab,DB09029
,847246,DB09035,10060795,20,4706,39,6651,0.289252904,0.724790667,0.399995105,1.275158817,0.454358776,DB0903510060795_,0.788868137,-0.321872401,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,nivolumab,DB09035
,847317,DB09029,10013786,62,11282,51,7219,0.20848403,0.777901661,0.52771801,1.151258645,0.359426932,DB0902910013786_,1.02324437,-0.251155163,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,847418,DB00878,10003054,44,1142,12,908,0.000555209,2.913931943,1.502015082,6.098556496,0.003366087,DB0087810003054_,5.69400446,1.069503352,female,10003054,Application site rash,10018065,General disorders and administration site conditions,Genrl,chlorhexidine,DB00878
,847437,DB09029,10042128,45,11299,13,7257,0.009902987,2.223146826,1.177579061,4.495220997,0.035278173,DB0902910042128_,3.34449083,0.798923682,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,847540,DB09029,10046735,164,11180,63,7207,0.000361536,1.678046948,1.245614286,2.284577883,0.00235718,DB0902910046735_,6.050289312,0.517630586,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,847852,DB00688,10074171,22,6468,62,5316,1.24410129214813e-07,0.29166796,0.170469786,0.481955261,2.21778246619963e-06,DB0068810074171_,13.01900275,-1.232139247,male,10074171,Aspergillus infection,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,847853,DB00864,10074171,27,6842,69,8323,0.000899373,0.476035335,0.292880105,0.753689515,0.00504805,DB0086410074171_,5.288753291,-0.742263193,NA,10074171,Aspergillus infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,848030,DB09073,10037377,113,20147,6,784,0.460493054,0.732900505,0.324989361,2.04545567,0.627883632,DB0907310037377_,0.465400429,-0.310745323,NA,10037377,Pulmonary embolism,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,palbociclib,DB09073
,848361,DB06282,10028813,78,1462,16,517,0.0529187,1.723551934,0.98649506,3.193198493,0.130527662,DB0628210028813_,2.036170106,0.544387239,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,levocetirizine,DB06282
,848725,DB01012,10057677,41,10591,55,8630,0.017651452,0.607452732,0.394816234,0.92797723,0.056037345,DB0101210057677_,2.881736942,-0.498480914,NA,10057677,Transplant,10042613,Surgical and medical procedures,Surg,cinacalcet,DB01012
,849490,DB00688,10051118,46,6444,23,5355,0.051878814,1.661938538,0.985403309,2.876592863,0.128574697,DB0068810051118_,2.051245243,0.507984715,NA,10051118,Drug ineffective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,849607,DB09122,10028245,53,1205,14,323,1,1.014753291,0.546550166,2.006362485,1,DB0912210028245_,0,0.01464552,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,peginterferon beta-1a,DB09122
,849614,DB09343,10000081,68,1451,78,1805,0.670748958,1.084459931,0.765763495,1.532709981,0.800249273,DB0934310000081_,0.222832009,0.081082104,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,tipiracil,DB09343
,849615,DB09343,10010774,51,1468,55,1828,0.488079887,1.15461791,0.767985154,1.73315673,0.651690533,DB0934310010774_,0.428185472,0.143769475,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,tipiracil,DB09343
,849812,DB09035,10048302,19,4707,54,6636,0.008316977,0.496076933,0.277294206,0.85172091,0.030708209,DB0903510048302_,3.483225281,-0.701024258,NA,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,nivolumab,DB09035
,849916,DB00210,10037087,65,820,14,335,0.037979848,1.895918482,1.035349638,3.710525519,0.101577157,DB0021010037087_,2.286936601,0.639703408,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,adapalene,DB00210
,852121,DB08868,10013578,37,9165,13,2498,0.488690247,0.775762072,0.402293645,1.593054068,0.652240436,DB0886810013578_,0.427342019,-0.253909414,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,853731,DB01240,10066400,64,5687,6,1570,0.005338417,2.944477312,1.277662118,8.336813778,0.021552919,DB0124010066400_,3.837244002,1.079931318,female,10066400,Emergency care,10042613,Surgical and medical procedures,Surg,epoprostenol,DB01240
,854621,DB06403,10029216,44,21427,12,6649,0.755677615,1.137794797,0.590311341,2.367994524,0.862950453,DB0640310029216_,0.147398002,0.129092001,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,ambrisentan,DB06403
,855266,DB01042,10042128,9,981,43,1285,0.000105773,0.274294632,0.11699056,0.573943436,0.000837169,DB0104210042128_,7.085484537,-1.293552452,male,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,melphalan,DB01042
,858448,DB06403,10028836,104,21367,19,6642,0.033013382,1.701429835,1.035787672,2.941776289,0.091309174,DB0640310028836_,2.393504016,0.531468977,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ambrisentan,DB06403
,859208,DB00181,10075580,30,9826,49,5822,1.06954726244837e-05,0.362784568,0.222070246,0.583779992,0.000115076,DB0018110075580_,9.069918383,-1.013946097,male,10075580,Medical device site infection,10021881,Infections and infestations,Infec,baclofen,DB00181
,859260,DB00471,10076573,78,14111,25,5440,0.508164656,1.20278663,0.7571061,1.972477566,0.66876728,DB0047110076573_,0.402319143,0.184641057,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,859261,DB00656,10076573,70,11943,42,6577,0.692291541,0.917837807,0.616536372,1.381215978,0.814579128,DB0065610076573_,0.205083706,-0.085734585,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,859262,DB00983,10076573,55,3446,28,1712,0.90692399,0.975858939,0.605891559,1.603982483,0.95853111,DB0098310076573_,0.04235326,-0.024437232,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,formoterol,DB00983
,859263,DB01175,10076573,76,10648,25,4867,0.162961587,1.389536858,0.872894042,2.282213867,0.301311573,DB0117510076573_,1.199610422,0.328970496,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,859585,DB00203,10013578,45,13833,17,8921,0.06759981,1.707067315,0.957333674,3.183564049,0.157022006,DB0020310013578_,1.851369318,0.534776878,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,sildenafil,DB00203
,861413,DB09037,10053762,118,2408,141,2694,0.610534823,0.936265489,0.722219762,1.212053767,0.752698475,DB0903710053762_,0.284090564,-0.065856201,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,pembrolizumab,DB09037
,861575,DB00115,10069868,36,18389,15,10457,0.381961153,1.364758291,0.728351371,2.68443158,0.552095073,DB0011510069868_,0.594035015,0.310977337,NA,10069868,Device issue,10077536,Product issues,Prod,cyanocobalamin,DB00115
,861772,DB06262,10000059,39,3761,28,4286,0.06559568,1.587180191,0.949922016,2.683904127,0.153486514,DB0626210000059_,1.874142576,0.461958977,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,droxidopa,DB06262
,861853,DB13867,10016807,54,4496,12,2542,0.001881401,2.543976739,1.340981281,5.234618091,0.009259925,DB1386710016807_,4.682059335,0.933728502,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,fluticasone,DB13867
,862740,DB00211,10016322,40,1396,39,1592,0.495781238,1.169580208,0.728773478,1.878364679,0.65811923,DB0021110016322_,0.418369163,0.156644888,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,midodrine,DB00211
,862747,DB00190,10033864,26,3271,51,4623,0.201002356,0.720550016,0.430269609,1.180274693,0.350202491,DB0019010033864_,1.049243746,-0.327740447,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,862777,DB00695,10076573,117,27932,71,20457,0.236568646,1.206881245,0.890597954,1.645392597,0.393819111,DB0069510076573_,0.931863583,0.188039549,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,862781,DB06228,10076573,73,15839,54,16022,0.090915991,1.367452015,0.948079128,1.982964108,0.196685335,DB0622810076573_,1.626150114,0.312949165,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,863352,DB01075,10035669,40,19908,52,11045,6.85832054712985e-05,0.426779121,0.275163973,0.657567689,0.000576683,DB0107510035669_,7.458218669,-0.851488679,NA,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,diphenhydramine,DB01075
,863852,DB05676,10039203,40,47089,24,25305,0.694720549,0.895649087,0.526775315,1.553556736,0.816264204,DB0567610039203_,0.203017197,-0.110206587,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,apremilast,DB05676
,863941,DB00996,10014062,42,38911,28,22397,0.537428081,0.863400811,0.522539164,1.446810119,0.693587525,DB0099610014062_,0.36587784,-0.146876256,NA,10014062,Eating disorder,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,864249,DB00374,10048908,91,17625,19,5705,0.094460845,1.550227127,0.937156764,2.694884162,0.202446355,DB0037410048908_,1.597280342,0.438401454,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,treprostinil,DB00374
,864961,DB00472,10076573,54,10705,36,4276,0.019229487,0.599181728,0.385201824,0.942001078,0.059947466,DB0047210076573_,2.814286668,-0.512190341,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,864962,DB00497,10076573,71,19196,61,16314,1,0.989185595,0.69214805,1.417354639,1,DB0049710076573_,0,-0.010873305,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,864963,DB01238,10076573,127,5123,78,3424,0.61372099,1.088231387,0.811563499,1.466873108,0.755369411,DB0123810076573_,0.280548363,0.084553798,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole,DB01238
,865020,DB13867,10015090,39,4511,17,2537,0.405678585,1.290190688,0.71124769,2.437491717,0.575273069,DB1386710015090_,0.552910448,0.254790028,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,865193,DB09078,10013968,33,760,61,995,0.134237501,0.708391054,0.444286772,1.112160515,0.261636713,DB0907810013968_,1.340798329,-0.344759001,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenvatinib,DB09078
,865201,DB09078,10047895,45,748,79,977,0.133328433,0.744126824,0.497769582,1.101152324,0.260434575,DB0907810047895_,1.345403602,-0.295543797,NA,10047895,Weight decreased,10022891,Investigations,Inv,lenvatinib,DB09078
,865203,DB09078,10051398,45,748,64,992,0.765320624,0.932505204,0.614701044,1.404670668,0.870521783,DB0907810051398_,0.138662497,-0.069880547,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,lenvatinib,DB09078
,865205,DB09078,10061428,79,714,117,939,0.446636795,0.888061866,0.647825862,1.212423773,0.614378321,DB0907810061428_,0.487144382,-0.118713869,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,lenvatinib,DB09078
,865400,DB00005,10076573,5140,122942,1807,40612,0.026127713,0.939630037,0.889354627,0.993080396,0.076016044,DB0000510076573_,2.576810862,-0.062269059,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,865937,DB08868,10028035,58,9144,19,2492,0.486600039,0.831934731,0.487184992,1.482226557,0.650507681,DB0886810028035_,0.430002173,-0.184001289,NA,10028035,Movement disorder,10029205,Nervous system disorders,Nerv,fingolimod,DB08868
,866097,DB09029,10003239,448,10896,273,6997,0.508429367,1.053808448,0.901729947,1.233231881,0.668962056,DB0902910003239_,0.402027937,0.052410695,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,secukinumab,DB09029
,866701,DB00374,10076065,119,17597,16,5708,0.000387629,2.412579688,1.424452478,4.361089329,0.002499716,DB0037410076065_,5.991578264,0.880696585,NA,10076065,Infusion site discharge,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,867015,DB06262,10012378,34,3766,23,4291,0.061653643,1.684212096,0.961629153,3.000385169,0.14648522,DB0626210012378_,1.92083074,0.521297856,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,droxidopa,DB06262
,867040,DB00863,10003285,43,10630,11,5829,0.02200231,2.143476419,1.085935834,4.613043264,0.066631802,DB0086310003285_,2.708573307,0.762429006,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,ranitidine,DB00863
,867214,DB00563,10076573,381,46265,101,15247,0.056329783,1.243172073,0.995019569,1.565114723,0.136690209,DB0056310076573_,1.99003816,0.217666237,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,867276,DB09029,10028411,56,11288,43,7227,0.408794837,0.833811911,0.549732269,1.272473848,0.578194807,DB0902910028411_,0.54784443,-0.181747428,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,secukinumab,DB09029
,867507,DB09029,10022052,133,11211,32,7238,7.9813336911257e-08,2.683191554,1.810323815,4.085363297,1.47479336429694e-06,DB0902910022052_,13.42699267,0.987006964,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,867508,DB09029,10022067,76,11268,46,7224,0.780909944,1.059224883,0.724062215,1.564564149,0.880700697,DB0902910022067_,0.127037442,0.057537398,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,867509,DB09029,10028334,65,11279,31,7239,0.207946499,1.345714037,0.86358919,2.138350247,0.358759064,DB0902910028334_,1.025104247,0.296924755,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,secukinumab,DB09029
,867667,DB09073,10055798,59,20201,7,783,0.011660454,0.326727837,0.148386582,0.850689905,0.040243571,DB0907310055798_,3.212805027,-1.118627757,male,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,palbociclib,DB09073
,867859,DB00930,10067482,210,1080,86,556,0.10749742,1.256954927,0.952505252,1.669132222,0.22241575,DB0093010067482_,1.503206902,0.228692071,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,colesevelam,DB00930
,867902,DB00451,10076573,275,46996,98,15321,0.469248889,0.914805602,0.723325184,1.165010928,0.635554545,DB0045110076573_,0.453257362,-0.089043694,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,867904,DB00641,10076573,68,14056,53,12422,0.523490869,1.133858406,0.779456554,1.657149262,0.681717293,DB0064110076573_,0.383140234,0.125626335,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,867905,DB01202,10076573,35,6679,28,5690,0.89930695,1.064918124,0.628515553,1.819784357,0.956490275,DB0120210076573_,0.044484657,0.062897917,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,levetiracetam,DB01202
,867906,DB09072,10076573,104,6367,58,2477,0.034036156,0.697613979,0.499396477,0.982622367,0.09346919,DB0907210076573_,2.370123418,-0.360089368,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium oxybate,DB09072
,868538,DB01281,10063829,127,8805,24,1774,0.912534935,1.066161171,0.682905529,1.730492438,0.960726604,DB0128110063829_,0.040065401,0.064064506,NA,10063829,Device malfunction,10077536,Product issues,Prod,abatacept,DB01281
,868985,DB00921,10076573,240,5605,158,4745,0.015940983,1.28589077,1.043524041,1.588011541,0.051687994,DB0092110076573_,2.962529739,0.251451684,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,buprenorphine,DB00921
,869006,DB00921,10071134,57,5788,23,4880,0.002250113,2.08930155,1.264821215,3.558891503,0.010705807,DB0092110071134_,4.536969015,0.736829823,NA,10071134,Product physical issue,10077536,Product issues,Prod,buprenorphine,DB00921
,869086,DB00688,10040070,56,6434,53,5325,0.4998571,0.874492874,0.588718362,1.300464344,0.661551516,DB0068810040070_,0.413167421,-0.134111133,NA,10040070,Septic shock,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,869116,DB09029,10010264,258,11086,150,7120,0.35589176,1.1046873,0.897739018,1.363195975,0.525584454,DB0902910010264_,0.64324439,0.099562309,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,869117,DB09029,10012378,95,11249,34,7236,0.002730921,1.797280515,1.201678683,2.746681362,0.012518707,DB0902910012378_,4.380531198,0.586274697,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,secukinumab,DB09029
,869207,DB00104,10069217,181,1300,101,976,0.025160606,1.34528265,1.033468162,1.758553884,0.073848087,DB0010410069217_,2.60574518,0.29660414,NA,10069217,Needle issue,10077536,Product issues,Prod,octreotide,DB00104
,869341,DB09029,10067482,65,11279,41,7229,1,1.016101289,0.676146321,1.542659708,1,DB0902910067482_,0,0.015973038,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,869499,DB01234,10060946,18,31607,32,32856,0.067363404,0.58473585,0.308958403,1.073886052,0.1566182,DB0123410060946_,1.853944281,-0.536595072,NA,10060946,Pneumonia bacterial,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,869758,DB09073,10010305,117,20143,12,778,0.003404256,0.376610478,0.20651457,0.753027161,0.014988419,DB0907310010305_,4.200477462,-0.97654384,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,palbociclib,DB09073
,870192,DB09029,10028735,64,11280,29,7241,0.135678242,1.41665307,0.899171297,2.281431015,0.263653022,DB0902910028735_,1.333121351,0.348297097,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,secukinumab,DB09029
,870202,DB09029,10039101,74,11270,36,7234,0.202410962,1.319401107,0.873509765,2.025615601,0.35179503,DB0902910039101_,1.044706573,0.277177927,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,secukinumab,DB09029
,870828,DB09029,10003246,137,11207,102,7168,0.256939462,0.859082169,0.658799571,1.123246976,0.417846548,DB0902910003246_,0.872641025,-0.151890705,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,secukinumab,DB09029
,871736,DB01222,10066967,41,9233,22,5383,0.794937421,1.08653656,0.631488239,1.917421364,0.888900097,DB0122210066967_,0.117770427,0.08299517,NA,10066967,Intentional device misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,budesonide,DB01222
,872688,DB08932,10015958,53,19390,17,6580,1,1.057955126,0.602474136,1.950527263,1,DB0893210015958_,0,0.056337918,NA,10015958,Eye pain,10015919,Eye disorders,Eye,macitentan,DB08932
,873014,DB00190,10076573,41,3256,34,4640,0.024566619,1.718292854,1.061422382,2.798219491,0.072542107,DB0019010076573_,2.623588094,0.541331271,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,carbidopa,DB00190
,873015,DB00190,10010264,52,3245,95,4579,0.150779105,0.772413166,0.538237257,1.097913526,0.285032095,DB0019010010264_,1.255153489,-0.258235684,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,873087,DB01390,10070863,35,1374,27,1490,0.20037157,1.405563899,0.821757382,2.428321228,0.349463653,DB0139010070863_,1.05135572,0.340438574,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium bicarbonate,DB01390
,873354,DB00211,10048959,28,1408,32,1599,1,0.993698552,0.573309167,1.713285662,1,DB0021110048959_,0,-0.006321386,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,midodrine,DB00211
,873400,DB00008,10067482,94,1431,88,1588,0.284909549,1.185310216,0.868736062,1.618482469,0.449470186,DB0000810067482_,0.799685754,0.170004526,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,peginterferon alfa-2a,DB00008
,873401,DB00008,10069327,34,1491,31,1645,0.454705711,1.209980957,0.717658576,2.046801934,0.622286185,DB0000810069327_,0.474355187,0.190604621,NA,10069327,Product quality issue,10077536,Product issues,Prod,peginterferon alfa-2a,DB00008
,873476,DB09029,10009887,41,11303,19,7251,0.289149597,1.384289886,0.784718899,2.527507529,0.454291522,DB0902910009887_,0.789016169,0.32518729,NA,10009887,Colitis,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,873477,DB09029,10058080,57,11287,37,7233,1,0.987215357,0.640684403,1.537775027,1,DB0902910058080_,0,-0.01286707,NA,10058080,Staphylococcal infection,10021881,Infections and infestations,Infec,secukinumab,DB09029
,874266,DB00688,10001052,27,6463,32,5346,0.190134759,0.697953108,0.40173302,1.204177012,0.336726326,DB0068810001052_,1.088484766,-0.359603359,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolate mofetil,DB00688
,874381,DB08932,10061218,48,19395,14,6583,0.769924189,1.163707124,0.630586322,2.287118287,0.873962496,DB0893210061218_,0.134717815,0.151610706,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,874492,DB04951,10056819,33,1849,32,3025,0.039453717,1.686890365,1.001711552,2.844136095,0.104556228,DB0495110056819_,2.25803029,0.522886814,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,pirfenidone,DB04951
,874600,DB00625,10037844,16,560,40,1096,0.473711862,0.782942924,0.405565932,1.444699335,0.639638162,DB0062510037844_,0.446852634,-0.24469548,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,efavirenz,DB00625
,874956,DB09033,10035664,33,2591,25,1644,0.501236354,0.837586464,0.481159514,1.474972787,0.662676234,DB0903310035664_,0.411468742,-0.17723078,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,vedolizumab,DB09033
,875060,DB00582,10070863,29,1101,57,1517,0.148281951,0.701095256,0.429201041,1.123333473,0.281628027,DB0058210070863_,1.267168132,-0.355111515,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,voriconazole,DB00582
,875188,DB00734,10076573,54,3996,82,4820,0.194335405,0.794351885,0.551220421,1.136703032,0.342157392,DB0073410076573_,1.072484436,-0.230228736,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,875797,DB08904,10076573,43,11567,10,3549,0.517291916,1.319297814,0.651959279,2.947748954,0.676906358,DB0890410076573_,0.390222334,0.277099636,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,certolizumab pegol,DB08904
,875809,DB00563,10024382,23,46623,68,15280,1.84554256863594e-23,0.110872217,0.065876961,0.18025133,2.5734793854958e-21,DB0056310024382_,47.40902812,-2.199376942,male,10024382,Leukoencephalopathy,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,876101,DB11065,10008479,34,3152,38,2650,0.236180623,0.752279321,0.457958468,1.231231262,0.393420574,DB1106510008479_,0.932876078,-0.284647587,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,pancrelipase amylase,DB11065
,876128,DB06655,10022061,82,3606,15,2104,5.67636210176382e-06,3.189123897,1.819458755,5.971505891,6.60483301659415e-05,DB0665510022061_,9.625123809,1.159746239,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,liraglutide,DB06655
,876485,DB00065,10076869,35,9429,17,4940,0.884215468,1.078642128,0.587612229,2.055409818,0.951764105,DB0006510076869_,0.049438063,0.075702961,NA,10076869,Product preparation error,10022117,"Injury, poisoning and procedural complications",Inj&P,infliximab,DB00065
,876501,DB09083,10016256,33,693,18,280,0.343222106,0.740959944,0.397588349,1.422359811,0.512517713,DB0908310016256_,0.668420006,-0.299808712,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ivabradine,DB09083
,876567,DB00193,10037162,123,19197,33,8669,0.00699073,1.683137289,1.13708986,2.554866081,0.026760552,DB0019310037162_,3.62082641,0.520659486,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,tramadol,DB00193
,876688,DB09045,10000081,44,2305,40,1684,0.37213107,0.803693585,0.509203398,1.271767802,0.541819375,DB0904510000081_,0.61282259,-0.218537196,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,dulaglutide,DB09045
,876689,DB09045,10025482,61,2288,28,1696,0.039131256,1.614701726,1.011377145,2.636119842,0.103890215,DB0904510025482_,2.264420566,0.47915025,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,dulaglutide,DB09045
,876690,DB09045,10033295,32,2317,32,1692,0.250946295,0.730321868,0.431326343,1.236556022,0.410819842,DB0904510033295_,0.889600502,-0.314269926,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,dulaglutide,DB09045
,876691,DB09045,10053762,34,2315,24,1700,1,1.040311896,0.596539734,1.840928841,1,DB0904510053762_,0,0.039520569,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,dulaglutide,DB09045
,876699,DB00921,10030995,43,5802,22,4881,0.061118754,1.644206354,0.960511943,2.890460968,0.145497121,DB0092110030995_,1.927598981,0.497257808,NA,10030995,Oral mucosal blistering,10017947,Gastrointestinal disorders,Gastr,buprenorphine,DB00921
,876728,DB00921,10052237,12,5833,44,4859,5.66519616199246e-07,0.227196464,0.109121241,0.43827021,8.66761822572595e-06,DB0092110052237_,11.65591652,-1.481940156,male,10052237,Drug detoxification,10042613,Surgical and medical procedures,Surg,buprenorphine,DB00921
,876840,DB09071,10027590,70,914,64,718,0.416330849,0.859280597,0.594517336,1.243672722,0.585576646,DB0907110027590_,0.535158198,-0.151659755,NA,10027590,Middle insomnia,10037175,Psychiatric disorders,Psych,tasimelteon,DB09071
,876895,DB09071,10041349,67,917,56,726,0.778492713,0.947282282,0.645121617,1.39523617,0.879245519,DB0907110041349_,0.128691104,-0.05415815,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,tasimelteon,DB09071
,877087,DB00158,10074903,77,16738,22,8082,0.03108783,1.689954526,1.039960778,2.853617473,0.087101596,DB0015810074903_,2.440680076,0.524701621,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,877140,DB00999,10022081,57,21373,19,12220,0.042208005,1.715221901,1.004671269,3.054961838,0.110101464,DB0099910022081_,2.206352936,0.539542461,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,877145,DB09122,10022086,44,1214,7,330,0.224053555,1.708098319,0.753962483,4.5374939,0.378608016,DB0912210022086_,0.971253868,0.535380658,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,peginterferon beta-1a,DB09122
,877208,DB08820,10061428,48,4353,29,3516,0.249583777,1.336864278,0.824090575,2.203582854,0.409073367,DB0882010061428_,0.893860757,0.290326781,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ivacaftor,DB08820
,877991,DB06655,10022093,56,3632,8,2111,2.13036361055025e-05,4.067813399,1.923984642,9.900991501,0.000210751,DB0665510022093_,8.464832023,1.403105607,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,liraglutide,DB06655
,878118,DB00008,10071411,49,1476,24,1652,0.000820716,2.284556268,1.367206763,3.913756681,0.004677986,DB0000810071411_,5.364887586,0.826171812,NA,10071411,Exposure via direct contact,10022117,"Injury, poisoning and procedural complications",Inj&P,peginterferon alfa-2a,DB00008
,878123,DB06655,10022094,45,3643,11,2108,0.00778125,2.366874756,1.202059542,5.086408691,0.029120833,DB0665510022094_,3.536301459,0.861570417,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,liraglutide,DB06655
,878411,DB00331,10076573,159,24787,89,20663,0.002599925,1.48926452,1.140995218,1.954186546,0.012028345,DB0033110076573_,4.420489363,0.398282387,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,878590,DB00476,10076573,106,17151,36,6141,0.848718648,1.054254689,0.715262337,1.586467675,0.924592575,DB0047610076573_,0.078402098,0.052834062,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,878594,DB01068,10076573,110,13653,49,6791,0.554813822,1.116600848,0.789457398,1.599304392,0.708321699,DB0106810076573_,0.344856911,0.110289114,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,878724,DB09034,10076573,51,1125,32,646,0.727044153,0.915212421,0.570286102,1.4880167,0.840403507,DB0903410076573_,0.173873136,-0.088599087,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,suvorexant,DB09034
,878855,DB09292,10030124,20,4509,62,8200,0.037130772,0.58666292,0.3351487,0.98617071,0.099860064,DB0929210030124_,2.303985437,-0.533304867,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,878856,DB09292,10047895,119,4410,296,7966,0.00344385,0.72621859,0.58016093,0.904396807,0.015127239,DB0929210047895_,4.19125827,-0.319904222,NA,10047895,Weight decreased,10022891,Investigations,Inv,sacubitril,DB09292
,878919,DB06605,10074903,40,14033,22,13011,0.055709623,1.685727721,0.977488802,2.979887242,0.135554497,DB0660510074903_,1.998381529,0.522197352,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,878978,DB00888,10003046,34,643,33,732,0.533508667,1.172778741,0.695944769,1.978347493,0.69022372,DB0088810003046_,0.370739503,0.159375926,NA,10003046,Application site irritation,10018065,General disorders and administration site conditions,Genrl,mechlorethamine,DB00888
,878994,DB09073,10016173,254,20006,15,775,0.142113036,0.655997085,0.387820317,1.195363137,0.272749527,DB0907310016173_,1.299201388,-0.421598933,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,palbociclib,DB09073
,879418,DB01012,10024733,55,10577,39,8646,0.533834457,1.152775641,0.750245283,1.786549269,0.690424322,DB0101210024733_,0.370448911,0.142172636,NA,10024733,Living in residential institution,10041244,Social circumstances,SocCi,cinacalcet,DB01012
,879518,DB09029,10037660,115,11229,92,7178,0.115201787,0.799066168,0.601142903,1.064592576,0.233961135,DB0902910037660_,1.452600267,-0.224311523,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,880201,DB09292,10005483,52,4477,164,8098,0.000412019,0.573545179,0.410595521,0.789773684,0.00262607,DB0929210005483_,5.942266927,-0.555918568,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,sacubitril,DB09292
,880202,DB09292,10047899,139,4390,267,7995,0.635368449,0.948107427,0.764131348,1.172205702,0.773416276,DB0929210047899_,0.256937855,-0.053287463,NA,10047899,Weight increased,10022891,Investigations,Inv,sacubitril,DB09292
,880293,DB00030,10076573,50,2156,43,1778,0.916130713,0.958915545,0.621811789,1.4842391,0.962507576,DB0003010076573_,0.038213342,-0.041952273,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin human,DB00030
,880295,DB00341,10076573,71,11334,29,5039,0.745480218,1.088475499,0.696493507,1.741640684,0.854760084,DB0034110076573_,0.156934453,0.084778092,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,880300,DB00758,10076573,55,8245,50,10024,0.141189335,1.337312375,0.894048154,2.004501354,0.271531858,DB0075810076573_,1.303675807,0.29066191,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,880302,DB00999,10076573,114,21316,55,12184,0.336173948,1.184715116,0.850789511,1.666998716,0.505257999,DB0099910076573_,0.682686091,0.169502337,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,880306,DB01136,10076573,49,9835,50,11065,0.68669984,1.102556598,0.727392728,1.670427638,0.811012999,DB0113610076573_,0.209471197,0.097631663,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,880307,DB01306,10076573,43,4165,34,3832,0.567115886,1.163567651,0.723147882,1.885658458,0.718305798,DB0130610076573_,0.330859898,0.151490847,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin aspart,DB01306
,880597,DB00820,10076573,26,11889,40,5776,4.33182485160632e-06,0.315810225,0.18483975,0.530987371,5.20631075557714e-05,DB0082010076573_,9.863053968,-1.152613801,male,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,tadalafil,DB00820
,881442,DB09029,10007882,75,11269,62,7208,0.13621125,0.773769503,0.54457351,1.102819968,0.264395577,DB0902910007882_,1.330308901,-0.25648125,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,secukinumab,DB09029
,881703,DB08820,10000087,64,4337,58,3487,0.521786069,0.88720017,0.610257615,1.292133924,0.680482388,DB0882010000087_,0.384953338,-0.119684651,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ivacaftor,DB08820
,881993,DB06413,10042458,74,1482,24,650,0.218029694,1.352203883,0.834322146,2.262641582,0.371223827,DB0641310042458_,0.990950092,0.301735768,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,armodafinil,DB06413
,882025,DB00813,10076573,102,10470,60,10108,0.002611588,1.64117546,1.180081752,2.299635821,0.012074863,DB0081310076573_,4.416629456,0.495412729,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,882092,DB00264,10076573,135,29472,95,24797,0.185383203,1.195633333,0.912292911,1.572212938,0.330695453,DB0026410076573_,1.10655741,0.178676031,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,882093,DB00381,10076573,132,29228,84,22803,0.149466627,1.225986285,0.925051081,1.63248089,0.28324256,DB0038110076573_,1.261451647,0.203745651,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,882094,DB00736,10076573,57,10534,19,5534,0.090593794,1.575998236,0.922533196,2.808455505,0.1961659,DB0073610076573_,1.628794547,0.454888872,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,esomeprazole,DB00736
,882198,DB09052,10013709,29,900,43,1016,0.28077162,0.761448344,0.454333119,1.259825419,0.444639819,DB0905210013709_,0.810490721,-0.272532944,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,blinatumomab,DB09052
,882564,DB00888,10059005,36,641,19,746,0.005657498,2.203934201,1.217165744,4.110620301,0.022587882,DB0088810059005_,3.7903417,0.790244036,NA,10059005,Application site discolouration,10018065,General disorders and administration site conditions,Genrl,mechlorethamine,DB00888
,882611,DB00490,10000059,63,4007,13,1563,0.038629732,1.890143951,1.026051031,3.754775136,0.102877669,DB0049010000059_,2.274214674,0.636652991,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,buspirone,DB00490
,882644,DB00182,10076308,46,5148,33,2819,0.239235173,0.763356191,0.476386356,1.235311413,0.396988416,DB0018210076308_,0.923848177,-0.270030527,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,amphetamine,DB00182
,882645,DB00422,10076308,37,3398,19,2930,0.079385313,1.679024579,0.938761104,3.098162433,0.177396122,DB0042210076308_,1.72937007,0.518213017,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,methylphenidate,DB00422
,882650,DB01065,10076308,37,4294,13,3038,0.030162799,2.013464317,1.043911498,4.135080727,0.085053819,DB0106510076308_,2.464471059,0.699856779,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,melatonin,DB01065
,882658,DB01255,10076573,89,2044,70,1508,0.743067673,0.938044594,0.673068997,1.311564888,0.852961276,DB0125510076573_,0.15904113,-0.063957789,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,lisdexamfetamine,DB01255
,882851,DB09072,10020466,51,6420,28,2507,0.166342212,0.71129388,0.438998909,1.174367016,0.305907665,DB0907210020466_,1.184471972,-0.340669601,NA,10020466,Hunger,10018065,General disorders and administration site conditions,Genrl,sodium oxybate,DB09072
,882884,DB00316,10076573,281,65193,129,36824,0.056448117,1.230443308,0.994971022,1.528218178,0.136888898,DB0031610076573_,1.988585644,0.207374517,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,882886,DB00335,10076573,53,8413,31,5434,0.737031288,1.104301146,0.694970401,1.78220857,0.848327581,DB0033510076573_,0.16448842,0.099212688,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,atenolol,DB00335
,882887,DB00338,10076573,158,33516,86,22186,0.149740034,1.216118011,0.928868889,1.601295588,0.283608359,DB0033810076573_,1.26016101,0.195663827,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,882888,DB00437,10076573,28,6893,38,11508,0.445078098,1.230143586,0.726444053,2.060042975,0.613107231,DB0043710076573_,0.48921543,0.207130899,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,allopurinol,DB00437
,882889,DB00722,10076573,116,25287,100,25932,0.219710643,1.189582671,0.902001387,1.571185389,0.373092205,DB0072210076573_,0.985929691,0.173602549,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,882891,DB01104,10076573,96,15367,39,7247,0.460503735,1.160831641,0.791376314,1.732290802,0.627883632,DB0110410076573_,0.465400429,0.14913668,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,882976,DB00422,10076573,44,3391,45,2904,0.453862121,0.837379246,0.538188292,1.302095333,0.62142274,DB0042210076573_,0.475743687,-0.177478209,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,methylphenidate,DB00422
,883026,DB09029,10011224,163,11181,79,7191,0.03991284,1.326974542,1.006475414,1.761785329,0.105517626,DB0902910011224_,2.248877271,0.28290157,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,secukinumab,DB09029
,883176,DB09027,10066901,46,5133,170,6982,1.32361896962637e-10,0.368090945,0.259225651,0.513638181,4.22481173243828e-09,DB0902710066901_,19.28229114,-0.999425238,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,ledipasvir,DB09027
,883185,DB00186,10076573,94,16807,44,9964,0.216598406,1.266545266,0.875592825,1.85709698,0.369394264,DB0018610076573_,0.995890739,0.236292931,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,883186,DB00588,10076573,95,16429,33,8435,0.060676096,1.478009573,0.984265272,2.270190603,0.144661572,DB0058810076573_,1.933358249,0.3906963,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,883187,DB00996,10076573,161,38792,76,22349,0.1564263,1.22042393,0.923018094,1.626046105,0.29262439,DB0099610076573_,1.228865438,0.199198282,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,883396,DB00182,10076573,69,5125,24,2828,0.050362926,1.586354314,0.981667512,2.646497863,0.125698097,DB0018210076573_,2.073872303,0.461438499,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,amphetamine,DB00182
,883400,DB09045,10022052,45,2304,15,1709,0.005650663,2.224839141,1.21241613,4.311956638,0.022569164,DB0904510022052_,3.791170732,0.799684617,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,dulaglutide,DB09045
,883443,DB01156,10076573,96,13526,41,6287,0.712814214,1.088325704,0.746594333,1.611526337,0.829334349,DB0115610076573_,0.187131889,0.084640464,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,883462,DB00003,10067671,26,2972,30,2563,0.284758752,0.747441789,0.423376573,1.311395706,0.449286221,DB0000310067671_,0.800095132,-0.291098851,NA,10067671,Disease complication,10018065,General disorders and administration site conditions,Genrl,dornase alfa,DB00003
,883504,DB00091,10018651,34,5476,33,2637,0.005558558,0.496179792,0.297479756,0.828558732,0.022268969,DB0009110018651_,3.804561109,-0.700816934,NA,10018651,Graft versus host disease,10021428,Immune system disorders,Immun,cyclosporine,DB00091
,883569,DB00531,10055181,28,7224,30,6486,0.512981847,0.83799696,0.481845796,1.453213857,0.673086193,DB0053110055181_,0.395881885,-0.176740806,NA,10055181,BK virus infection,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,883695,DB00285,10051076,55,10896,21,3697,0.691547561,0.888659361,0.527961839,1.549239969,0.814013463,DB0028510051076_,0.205778373,-0.118041287,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,884268,DB08816,10063934,44,1107,88,1814,0.31326612,0.819401698,0.552726606,1.199818992,0.480841948,DB0881610063934_,0.732216654,-0.199180841,NA,10063934,Vascular stent thrombosis,10018065,General disorders and administration site conditions,Genrl,ticagrelor,DB08816
,884459,DB00169,10076573,197,38494,53,18122,0.000176634,1.749844871,1.285453655,2.418164251,0.001298146,DB0016910076573_,6.646818478,0.559527139,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,884461,DB00669,10076573,116,6261,17,1080,0.621212218,1.177009705,0.700715443,2.098256412,0.761528748,DB0066910076573_,0.272427355,0.162977074,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,sumatriptan,DB00669
,884463,DB13961,10076573,49,9408,21,6393,0.087128868,1.585519843,0.932186539,2.786235466,0.190293501,DB1396110076573_,1.659187657,0.46091233,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,fish oil,DB13961
,884464,DB14513,10076573,48,7129,14,3550,0.079539015,1.707235227,0.924316359,3.357593342,0.177658312,DB1451310076573_,1.727893168,0.534875236,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium,DB14513
,884472,DB09292,10037844,162,4367,181,8081,5.59184056067075e-06,1.656222807,1.326983846,2.065519717,6.51947345918078e-05,DB0929210037844_,9.63813185,0.504539592,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,sacubitril,DB09292
,884663,DB00003,10054112,343,2655,281,2312,0.495700398,1.062957936,0.896212892,1.261434421,0.658054797,DB0000310054112_,0.418467074,0.061055527,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,dornase alfa,DB00003
,884819,DB00688,10022000,40,6450,33,5345,1,1.004462956,0.616690996,1.646263446,1,DB0068810022000_,0,0.004453026,NA,10022000,Influenza,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,885259,DB09045,10013709,76,2273,49,1675,0.520159344,1.14290142,0.783064657,1.681520948,0.679255204,DB0904510013709_,0.38675837,0.133570135,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dulaglutide,DB09045
,885369,DB00046,10076573,50,5409,39,4653,0.670655744,1.102821836,0.709654698,1.725049205,0.800208186,DB0004610076573_,0.222883353,0.097872201,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin lispro,DB00046
,885501,DB09292,10053762,31,4498,21,8241,0.0004036,2.704381861,1.503015042,4.957980247,0.002582434,DB0929210053762_,5.959022964,0.994873369,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,sacubitril,DB09292
,885513,DB09034,10040984,33,1143,22,656,0.57379971,0.860968757,0.482485772,1.564235952,0.72365058,DB0903410040984_,0.323446628,-0.149697063,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,suvorexant,DB09034
,885537,DB09083,10013573,48,678,13,285,0.191968299,1.551466585,0.811891531,3.171495444,0.339116686,DB0908310013573_,1.081411023,0.439200668,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ivabradine,DB09083
,885539,DB09083,10053762,346,380,67,231,3.58840124108993e-14,3.135889391,2.285774259,4.341018523,1.95079889600928e-12,DB0908310053762_,26.96278214,1.142912831,female,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ivabradine,DB09083
,886061,DB06186,10020850,25,2184,31,3615,0.332145228,1.334756986,0.75343955,2.342818713,0.50100065,DB0618610020850_,0.691147881,0.288749242,NA,10020850,Hyperthyroidism,10014698,Endocrine disorders,Endo,ipilimumab,DB06186
,886062,DB09035,10020850,27,4699,39,6651,1,0.979898079,0.57596367,1.644657692,1,DB0903510020850_,0,-0.020306714,NA,10020850,Hyperthyroidism,10014698,Endocrine disorders,Endo,nivolumab,DB09035
,886674,DB00433,10061309,67,7589,35,5985,0.056665804,1.509638428,0.987202425,2.344929627,0.13722689,DB0043310061309_,1.986119592,0.41187017,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prochlorperazine,DB00433
,887973,DB00741,10022000,39,4055,25,3149,0.527263186,1.211420393,0.713126077,2.093443001,0.684879755,DB0074110022000_,0.378511996,0.191793549,NA,10022000,Influenza,10021881,Infections and infestations,Infec,hydrocortisone,DB00741
,889119,DB00688,10033775,36,6454,22,5356,0.291130617,1.357937435,0.776437299,2.426278775,0.456517123,DB0068810033775_,0.78412907,0.305966957,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,mycophenolate mofetil,DB00688
,890011,DB06403,10019304,44,21427,12,6649,0.755677615,1.137794797,0.590311341,2.367994524,0.862950453,DB0640310019304_,0.147398002,0.129092001,NA,10019304,Heart rate irregular,10022891,Investigations,Inv,ambrisentan,DB06403
,890448,DB06403,10040984,42,21429,15,6646,0.640530892,0.868420715,0.471423506,1.686988501,0.777463208,DB0640310040984_,0.251718957,-0.141078987,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,ambrisentan,DB06403
,891496,DB00559,10062355,113,9546,36,3270,0.776923848,1.075225876,0.731316296,1.614875838,0.878478692,DB0055910062355_,0.129563626,0.072530757,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,891635,DB01238,10061114,44,5206,32,3470,0.725216887,0.916500727,0.566907469,1.49646924,0.838918512,DB0123810061114_,0.175641703,-0.087192418,NA,10061114,Economic problem,10041244,Social circumstances,SocCi,aripiprazole,DB01238
,891725,DB00820,10039101,117,11798,25,5791,6.73055597630456e-05,2.297067178,1.479738117,3.69804866,0.000567847,DB0082010039101_,7.473658932,0.831633169,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,892128,DB00836,10014418,22,5513,41,4034,0.000301685,0.392669518,0.222397385,0.676007115,0.002027039,DB0083610014418_,6.201179034,-0.934786942,NA,10014418,Electrolyte imbalance,10027433,Metabolism and nutrition disorders,Metab,loperamide,DB00836
,892721,DB01611,10062355,62,11851,9,2352,0.520575119,1.367168881,0.674432177,3.133918354,0.679679962,DB0161110062355_,0.386133235,0.312742091,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,894072,DB00158,10076573,129,16686,38,8066,0.006174641,1.640983433,1.133768303,2.425057177,0.024216716,DB0015810076573_,3.720712153,0.495295717,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,895309,DB00904,10052015,50,23019,78,14378,3.61802293954421e-07,0.400401726,0.274791277,0.578780499,5.77762654713971e-06,DB0090410052015_,12.06151759,-0.915286921,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,ondansetron,DB00904
,896008,DB09076,10016173,31,777,19,591,0.561230399,1.240821282,0.671527638,2.349287306,0.713688488,DB0907610016173_,0.337308704,0.215773485,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,umeclidinium,DB09076
,897156,DB00455,10076573,71,9330,28,5090,0.16978311,1.383334525,0.880438777,2.228750439,0.310659659,DB0045510076573_,1.169057311,0.324496907,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,897339,DB00787,10051398,24,16976,35,17213,0.192831966,0.695297818,0.39547944,1.203133536,0.340196538,DB0078710051398_,1.078231775,-0.36341501,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,acyclovir,DB00787
,897988,DB05676,10048908,52,47077,28,25301,1,0.998100298,0.61866581,1.641766695,1,DB0567610048908_,0,-0.001901509,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,apremilast,DB05676
,898172,DB09076,10033371,37,771,14,596,0.029762082,2.042004075,1.066489325,4.12904872,0.084194837,DB0907610033371_,2.474621674,0.713931715,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,umeclidinium,DB09076
,898628,DB06605,10076573,104,13969,52,12981,0.000204815,1.858494753,1.318675948,2.647321065,0.001469713,DB0660510076573_,6.522687959,0.619766888,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,899030,DB09029,10017533,53,11291,19,7251,0.029089482,1.791325168,1.04219963,3.207136458,0.082701535,DB0902910017533_,2.492517116,0.582955663,NA,10017533,Fungal infection,10021881,Infections and infestations,Infec,secukinumab,DB09029
,899083,DB09303,10007559,42,26189,27,18932,0.714602221,1.124542925,0.677023564,1.897324893,0.830822547,DB0930310007559_,0.185339048,0.117376664,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,evolocumab,DB09303
,899145,DB09303,10005470,32,26199,85,18874,2.29377818238409e-11,0.271220977,0.174653838,0.411873636,8.26483338231197e-10,DB0930310005470_,20.91384136,-1.304821376,male,10005470,Blood creatine phosphokinase increased,10022891,Investigations,Inv,evolocumab,DB09303
,899612,DB09029,10003988,106,11238,72,7198,0.700230395,0.942970269,0.691403522,1.292266997,0.819879108,DB0902910003988_,0.198598379,-0.058720525,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,secukinumab,DB09029
,900228,DB09029,10005191,71,11273,28,7242,0.029796493,1.628951635,1.037173229,2.623680623,0.084259193,DB0902910005191_,2.473857604,0.487936639,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,900621,DB00213,10076573,70,18825,42,13379,0.442405333,1.184480273,0.796132367,1.781487347,0.610467266,DB0021310076573_,0.493530605,0.16930409,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,900622,DB00904,10076573,67,23002,17,14439,0.000440178,2.473925806,1.435504216,4.496506678,0.002777262,DB0090410076573_,5.886289832,0.905806284,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,900630,DB11089,10076573,33,10142,18,8389,0.161517149,1.516413388,0.828674785,2.862618557,0.299494075,DB1108910076573_,1.205660646,0.416347934,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,902193,DB09029,10069868,289,11055,175,7095,0.563421001,1.059876443,0.873259913,1.289268852,0.71536668,DB0902910069868_,0.334960029,0.058152338,NA,10069868,Device issue,10077536,Product issues,Prod,secukinumab,DB09029
,902628,DB09029,10037162,281,11063,131,7139,0.002164019,1.384178026,1.118494687,1.720147447,0.010380737,DB0902910037162_,4.567803381,0.325106481,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,secukinumab,DB09029
,902674,DB09029,10037884,32,11312,21,7249,1,0.976483793,0.545510144,1.783251039,1,DB0902910037884_,0,-0.023797126,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,902836,DB00126,10076308,73,10098,28,5917,0.06227013,1.527637002,0.974499066,2.456699487,0.14768297,DB0012610076308_,1.912687398,0.423722098,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ascorbic acid,DB00126
,902922,DB09029,10060795,32,11312,27,7243,0.288654134,0.758890829,0.440045266,1.317847786,0.453689354,DB0902910060795_,0.790342557,-0.275897347,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,secukinumab,DB09029
,903030,DB09029,10028596,34,11310,45,7225,0.001629351,0.482672025,0.29954613,0.771345913,0.008217884,DB0902910028596_,4.801442579,-0.728417894,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,secukinumab,DB09029
,903330,DB09029,10073317,261,11083,179,7091,0.488957411,0.93290954,0.766462817,1.13749433,0.652414811,DB0902910073317_,0.427074707,-0.069447039,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,903411,DB00601,10066901,22,883,31,880,0.264717268,0.707403506,0.386949855,1.273050015,0.426665708,DB0060110066901_,0.851754459,-0.346154046,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,linezolid,DB00601
,903419,DB00019,10056871,211,18801,114,9415,0.515684318,0.926870076,0.733527447,1.176108252,0.675424785,DB0001910056871_,0.392413475,-0.075941879,NA,10056871,Device failure,10077536,Product issues,Prod,pegfilgrastim,DB00019
,903714,DB00115,10076573,87,18338,32,10440,0.035357857,1.547788207,1.020509594,2.401280183,0.09618736,DB0011510076573_,2.341457319,0.436826949,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,903715,DB00153,10076573,36,7387,15,3424,0.880159417,1.112426484,0.593101865,2.189934661,0.949694712,DB0015310076573_,0.051614701,0.106543651,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,ergocalciferol,DB00153
,903719,DB01065,10076573,32,4299,20,3031,0.777829376,1.128094172,0.624322104,2.085446031,0.878859624,DB0106510076573_,0.129130094,0.120529635,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,melatonin,DB01065
,903720,DB01076,10076573,147,25600,123,25460,0.160943801,1.1885807,0.928429546,1.523728426,0.298756842,DB0107610076573_,1.208125273,0.172759906,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,903728,DB01012,10076573,55,10577,41,8644,0.681955854,1.096332689,0.71763414,1.686713577,0.807641966,DB0101210076573_,0.213636429,0.091970691,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,cinacalcet,DB01012
,904135,DB00836,10003119,31,5504,50,4025,0.000614148,0.453431057,0.27944914,0.725329812,0.003670088,DB0083610003119_,5.607539531,-0.790912045,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,loperamide,DB00836
,904493,DB00555,10076573,49,6998,33,3453,0.194498213,0.732659831,0.460812374,1.178445846,0.342385719,DB0055510076573_,1.071817343,-0.311073763,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,lamotrigine,DB00555
,904494,DB09029,10076573,138,11206,78,7192,0.400202746,1.135513364,0.852623381,1.521268238,0.57006065,DB0902910076573_,0.562012521,0.127084852,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,904495,DB00490,10033775,43,4027,13,1563,0.549193901,1.283739731,0.675347816,2.609555908,0.703578901,DB0049010033775_,0.351575254,0.249777483,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,buspirone,DB00490
,904589,DB01065,10070863,54,4277,32,3019,0.508924668,1.191108807,0.753335032,1.911218008,0.669437756,DB0106510070863_,0.401317089,0.174884644,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,melatonin,DB01065
,904656,DB00047,10076573,83,9202,58,8460,0.127392221,1.315620596,0.928181596,1.875575317,0.251928264,DB0004710076573_,1.3786109,0.274308491,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,904658,DB08895,10005839,50,28064,14,6632,0.528045115,0.844021073,0.459040716,1.654261185,0.685483299,DB0889510005839_,0.377631143,-0.169577816,NA,10005839,Blood triglycerides increased,10022891,Investigations,Inv,tofacitinib,DB08895
,904929,DB00829,10076573,45,8007,23,4431,0.800802207,1.082722262,0.640442715,1.877458429,0.892288513,DB0082910076573_,0.113965754,0.079478482,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,904963,DB00688,10073755,29,6461,42,5336,0.022597284,0.570284309,0.34209186,0.938773513,0.067959911,DB0068810073755_,2.688837291,-0.561620255,NA,10073755,Pneumocystis jirovecii pneumonia,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,904964,DB00864,10073755,40,6829,46,8346,0.828179312,1.062700983,0.677013846,1.661968167,0.909674858,DB0086410073755_,0.094668042,0.060813764,NA,10073755,Pneumocystis jirovecii pneumonia,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,905175,DB00080,10044565,40,600,71,842,0.271813851,0.790728155,0.515230333,1.199459459,0.434667341,DB0008010044565_,0.833174274,-0.234801043,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,daptomycin,DB00080
,905179,DB01024,10044565,35,2176,28,2092,0.526330826,1.201694062,0.707396191,2.058660501,0.684187125,DB0102410044565_,0.379523825,0.18373228,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,mycophenolic acid,DB01024
,905495,DB01012,10028810,46,10586,39,8646,0.913133302,0.963319556,0.614413857,1.517198571,0.961104948,DB0101210028810_,0.039671669,-0.037370089,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,cinacalcet,DB01012
,905514,DB00091,10073317,55,5455,13,2657,0.018703852,2.060549069,1.108983349,4.11941195,0.058614694,DB0009110073317_,2.836769871,0.722972485,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclosporine,DB00091
,905550,DB00196,10028098,8,5075,55,3230,2.90988262398759e-15,0.092604205,0.038039515,0.195881591,1.84304252461479e-13,DB0019610028098_,29.32218846,-2.379420728,male,10028098,Mucormycosis,10021881,Infections and infestations,Infec,fluconazole,DB00196
,905866,DB06262,10039906,47,3753,46,4268,0.530866363,1.161922481,0.755216294,1.788614069,0.687850894,DB0626210039906_,0.374183189,0.150075945,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,906430,DB00019,10054112,67,18945,49,9480,0.048257302,0.68420428,0.46592554,1.011031087,0.121807576,DB0001910054112_,2.105312725,-0.379498751,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,pegfilgrastim,DB00019
,906606,DB09045,10022061,65,2284,25,1699,0.004841156,1.933756618,1.196439035,3.215912717,0.019949796,DB0904510022061_,3.914536362,0.659464545,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,dulaglutide,DB09045
,906708,DB00921,10022061,62,5783,105,4798,6.9551147616017e-06,0.48992986,0.351148635,0.678686556,7.90210466862765e-05,DB0092110022061_,9.445796327,-0.713493042,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,906904,DB00973,10076573,50,3801,23,2998,0.03285725,1.714520382,1.02422676,2.951182356,0.090982651,DB0097310076573_,2.397086434,0.539133381,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,ezetimibe,DB00973
,906909,DB04951,10034972,27,1855,82,2975,0.003669015,0.528135055,0.327264182,0.828354854,0.015918142,DB0495110034972_,4.140295791,-0.638403242,NA,10034972,Photosensitivity reaction,10040785,Skin and subcutaneous tissue disorders,Skin,pirfenidone,DB04951
,907052,DB01024,10051358,37,2174,35,2085,1,1.013863281,0.618566968,1.664827471,1,DB0102410051358_,0,0.013768065,NA,10051358,Post transplant lymphoproliferative disorder,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,mycophenolic acid,DB01024
,907135,DB01012,10060933,197,10435,134,8551,0.106018163,1.204707068,0.960524857,1.514705133,0.22022186,DB0101210060933_,1.513119785,0.18623644,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,cinacalcet,DB01012
,907142,DB09035,10035528,28,4698,41,6649,1,0.96653451,0.574733025,1.603787477,1,DB0903510035528_,0,-0.034038275,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,nivolumab,DB09035
,907430,DB09035,10059282,25,4701,31,6659,0.683739875,1.142328155,0.645760575,2.002117768,0.8088255,DB0903510059282_,0.212172083,0.133068421,NA,10059282,Metastases to central nervous system,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,nivolumab,DB09035
,907509,DB00879,10028411,8,1769,45,3667,0.007237821,0.368573743,0.149737975,0.792234464,0.02748427,DB0087910028411_,3.594141448,-0.99811447,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,emtricitabine,DB00879
,907680,DB05829,10003239,48,1558,6,203,1,1.042342454,0.437805,3.018254888,1,DB0582910003239_,0,0.04147054,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,parathyroid hormone,DB05829
,907681,DB05829,10019211,95,1511,7,202,0.150909963,1.813822712,0.830753175,4.698295943,0.285176921,DB0582910019211_,1.254645518,0.595436613,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,parathyroid hormone,DB05829
,907782,DB00186,10017412,52,16849,24,9984,0.343084666,1.283869859,0.776785277,2.179192863,0.512414368,DB0018610017412_,0.668621669,0.249878844,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,lorazepam,DB00186
,907978,DB05259,10076573,72,11198,19,2709,0.69208569,0.916733674,0.545737286,1.612784627,0.814373371,DB0525910076573_,0.205336332,-0.086938281,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,glatiramer,DB05259
,908192,DB09029,10040829,32,11312,34,7236,0.042946512,0.602084627,0.359336496,1.006584775,0.111584942,DB0902910040829_,2.192969166,-0.507357267,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,908308,DB11065,10054112,227,2959,211,2477,0.295572029,0.900601315,0.737594524,1.09998879,0.461434529,DB1106510054112_,0.7734151,-0.10469261,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,pancrelipase amylase,DB11065
,908468,DB00476,10021030,269,16988,88,6089,0.505510715,1.095648561,0.856560644,1.412777451,0.666399978,DB0047610021030_,0.405865222,0.091346481,NA,10021030,Hypomania,10037175,Psychiatric disorders,Psych,duloxetine,DB00476
,908518,DB09029,10040849,43,11301,24,7246,0.618161169,1.148810466,0.680994863,1.98094811,0.759074365,DB0902910040849_,0.275655529,0.13872703,NA,10040849,Skin fissures,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,908520,DB09029,10002855,93,11251,41,7229,0.050226301,1.457396156,0.997685263,2.161822649,0.125422604,DB0902910002855_,2.076066408,0.376651388,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,secukinumab,DB09029
,909227,DB09292,10021097,484,4045,1125,7137,1.59012328507225e-06,0.759100624,0.676318331,0.851162221,2.1701137356243e-05,DB0929210021097_,10.73814589,-0.275620936,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,sacubitril,DB09292
,909647,DB09292,10012735,109,4420,198,8064,1,1.004360529,0.785252527,1.279107044,1,DB0929210012735_,0,0.00435105,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,sacubitril,DB09292
,909874,DB05259,10051572,40,11230,11,2717,0.722926864,0.87976997,0.442317713,1.903833932,0.836987738,DB0525910051572_,0.177945858,-0.128094803,NA,10051572,Injection site discolouration,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,910151,DB00355,10021789,82,1711,50,1213,0.469892788,1.162587685,0.801372041,1.700908551,0.636179617,DB0035510021789_,0.452274338,0.150648284,NA,10021789,Infection,10021881,Infections and infestations,Infec,aztreonam,DB00355
,910154,DB08820,10037660,41,4360,49,3496,0.069429599,0.670965855,0.430965682,1.039862769,0.160280784,DB0882010037660_,1.830828103,-0.399037031,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ivacaftor,DB08820
,910165,DB09029,10040844,91,11253,77,7193,0.080268709,0.75545188,0.550708566,1.038529054,0.178855001,DB0902910040844_,1.721179852,-0.280439192,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,910717,DB00927,10062355,55,7442,24,4992,0.084311149,1.537169598,0.934282379,2.60032628,0.185589025,DB0092710062355_,1.684220591,0.429942802,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,famotidine,DB00927
,910972,DB01373,10076573,120,22600,24,7357,0.032090777,1.62757695,1.042665107,2.641445358,0.089302426,DB0137310076573_,2.415726625,0.487092375,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,911499,DB09292,10019301,25,4504,47,8215,1,0.97017893,0.571396143,1.611085568,1,DB0929210019301_,0,-0.03027476,NA,10019301,Heart rate decreased,10022891,Investigations,Inv,sacubitril,DB09292
,911518,DB09029,10022000,146,11198,81,7189,0.305323644,1.15719639,0.874526012,1.540175328,0.47213978,DB0902910022000_,0.750480192,0.146000175,NA,10022000,Influenza,10021881,Infections and infestations,Infec,secukinumab,DB09029
,911663,DB09035,10040047,96,4630,147,6543,0.554408627,0.922880586,0.70401842,1.205222484,0.707941935,DB0903510040047_,0.345393201,-0.080255429,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,nivolumab,DB09035
,911702,DB00230,10076573,66,19608,25,8626,0.570163636,1.161381569,0.722379109,1.922476885,0.720856239,DB0023010076573_,0.327315553,0.149610304,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,911821,DB09107,10020751,48,1167,34,969,0.500071243,1.172152617,0.733186905,1.892243129,0.661718316,DB0910710020751_,0.412915318,0.158841902,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,methoxy polyethylene glycol-epoetin beta,DB09107
,912346,DB09029,10042609,46,11298,23,7247,0.387188419,1.282852915,0.761022841,2.219393074,0.557267673,DB0902910042609_,0.584709593,0.249086438,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,secukinumab,DB09029
,912447,DB09292,10033775,22,4507,31,8231,0.388252958,1.296003101,0.714070333,2.31485445,0.558242383,DB0929210033775_,0.582962033,0.259284991,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,912512,DB00153,10013710,34,7389,18,3421,0.655278978,0.874547233,0.479443832,1.64736503,0.788963159,DB0015310013710_,0.237035652,-0.134048975,NA,10013710,Drug interaction,10018065,General disorders and administration site conditions,Genrl,ergocalciferol,DB00153
,912521,DB00285,10076573,70,10881,21,3697,0.717024597,1.132544064,0.685979077,1.945221498,0.832718627,DB0028510076573_,0.183059477,0.124466486,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,912701,DB00688,10001053,21,6469,46,5332,0.000173889,0.376311921,0.213010745,0.644432243,0.001281557,DB0068810001053_,6.659679401,-0.977336902,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,mycophenolate mofetil,DB00688
,912942,DB00619,10059866,28,2871,41,2453,0.028891346,0.583562267,0.346434047,0.969974459,0.082240527,DB0061910059866_,2.498107067,-0.538604121,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,imatinib,DB00619
,913609,DB10631,10025482,45,1251,7,204,1,1.048280713,0.460778127,2.793363001,1,DB1063110025482_,0,0.047151406,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,cranberry,DB10631
,913922,DB00635,10028098,22,33031,111,23683,9.79659504800844e-23,0.142129106,0.085573527,0.2260754,1.3038151941109e-20,DB0063510028098_,45.78640713,-1.951019435,male,10028098,Mucormycosis,10021881,Infections and infestations,Infec,prednisone,DB00635
,913981,DB09029,10012174,39,11305,16,7254,0.165681644,1.564016858,0.853348552,3.000259899,0.305042694,DB0902910012174_,1.187303532,0.447257421,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,secukinumab,DB09029
,914008,DB01050,10076308,103,18005,49,9322,0.668477046,1.088315267,0.766547732,1.563716237,0.798551101,DB0105010076308_,0.224956317,0.084630874,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,914232,DB09292,10047302,6,4523,44,8218,0.000288795,0.247785653,0.086223209,0.584224936,0.001955429,DB0929210047302_,6.237145674,-1.395191207,male,10047302,Ventricular tachycardia,10007541,Cardiac disorders,Card,sacubitril,DB09292
,914236,DB06605,10073085,116,13957,95,12938,0.406636026,1.131898003,0.854610923,1.502173925,0.576211108,DB0660510073085_,0.551281178,0.123895872,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,914268,DB09035,10038695,56,4670,98,6592,0.21704171,0.806622744,0.568917271,1.134014087,0.369946265,DB0903510038695_,0.994397514,-0.214899199,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nivolumab,DB09035
,917752,DB00003,10037844,33,2965,20,2573,0.215931963,1.431761453,0.795341999,2.640074538,0.368508742,DB0000310037844_,0.998290846,0.358905471,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dornase alfa,DB00003
,918022,DB11362,10011224,400,6083,99,2070,0.005596307,1.374831077,1.094138077,1.741013558,0.022387783,DB1136210011224_,3.799239879,0.31833087,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,918023,DB11362,10019211,2430,4053,631,1538,9.27700451295164e-13,1.461290749,1.313659576,1.62668064,4.17544629491325e-11,DB1136210019211_,23.89921477,0.37932012,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,918372,DB08895,10006002,66,28048,7,6639,0.036705849,2.231681,1.024091684,5.769551529,0.098968431,DB0889510006002_,2.312954356,0.802755113,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,918464,DB08931,10048908,54,6523,8,2438,0.009589152,2.52248014,1.190923538,6.147338388,0.034435531,DB0893110048908_,3.368666374,0.9252426,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,riociguat,DB08931
,918797,DB01261,10076573,55,3726,35,3268,0.166559701,1.378204028,0.883519521,2.175664992,0.3062089,DB0126110076573_,1.183487732,0.320781222,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,sitagliptin,DB01261
,921214,DB08932,10028164,76,19367,13,6584,0.019806953,1.987521809,1.094654136,3.905354458,0.061315012,DB0893210028164_,2.791730565,0.68688854,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,macitentan,DB08932
,921268,DB00175,10076573,41,8090,22,6084,0.250691546,1.401494453,0.814576679,2.473162633,0.410505065,DB0017510076573_,0.890367012,0.337539134,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,921269,DB00678,10076573,86,15513,61,10663,0.866549128,0.969048329,0.689284182,1.369698932,0.939752195,DB0067810076573_,0.062139061,-0.031440793,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,921894,DB00281,10076573,54,11404,24,5647,0.718547883,1.114136941,0.676225269,1.886588224,0.833790884,DB0028110076573_,0.181772647,0.108080061,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,lidocaine,DB00281
,921898,DB01050,10076573,110,17998,39,9332,0.045894629,1.462422625,1.005521596,2.166912625,0.117280199,DB0105010076573_,2.143189346,0.380094393,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,921899,DB01222,10076573,63,9211,20,5385,0.016265029,1.841503978,1.097133349,3.219800714,0.052518431,DB0122210076573_,2.946591106,0.610582617,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,budesonide,DB01222
,922520,DB09029,10021789,141,11203,79,7191,0.366313662,1.145662864,0.862248324,1.531252086,0.535902187,DB0902910021789_,0.623803621,0.13598339,NA,10021789,Infection,10021881,Infections and infestations,Infec,secukinumab,DB09029
,923015,DB00287,10015958,47,1354,18,799,0.150564066,1.540543126,0.870852353,2.839020229,0.284738218,DB0028710015958_,1.256185055,0.432135033,NA,10015958,Eye pain,10015919,Eye disorders,Eye,travoprost,DB00287
,923072,DB09035,10003658,38,4688,67,6623,0.319641878,0.80128015,0.522551066,1.212855626,0.487823652,DB0903510003658_,0.717801307,-0.221544642,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,nivolumab,DB09035
,923122,DB00820,10076309,65,11850,40,5776,0.252394356,0.792100877,0.525446891,1.207152295,0.4125096,DB0082010076309_,0.885495801,-0.233066526,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tadalafil,DB00820
,923457,DB00381,10075192,24,29336,45,22842,0.000381244,0.415276114,0.241917451,0.696500171,0.002463977,DB0038110075192_,6.005978387,-0.878811644,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,amlodipine,DB00381
,924772,DB00997,10054889,21,5310,37,3477,0.000231254,0.371685897,0.20633028,0.653076146,0.001626529,DB0099710054889_,6.421307159,-0.989706145,NA,10054889,Transaminases increased,10022891,Investigations,Inv,doxorubicin,DB00997
,924926,DB00921,10069299,32,5813,18,4885,0.200625826,1.493911685,0.812470261,2.83045588,0.349747871,DB0092110069299_,1.050542752,0.401397972,NA,10069299,Product packaging quantity issue,10077536,Product issues,Prod,buprenorphine,DB00921
,925333,DB00425,10076573,48,12647,27,7457,0.90502212,1.048225185,0.640408679,1.748807597,0.957667115,DB0042510076573_,0.043255041,0.047098434,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,925334,DB00863,10076573,61,10612,27,5813,0.373899826,1.23750623,0.773710835,2.027836999,0.543701976,DB0086310076573_,0.60935402,0.21309825,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,925363,DB00571,10000059,63,5060,24,2585,0.254525521,1.341002386,0.82377204,2.249940306,0.415218205,DB0057110000059_,0.878951102,0.293417384,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,propranolol,DB00571
,925677,DB08877,10076573,31,3258,25,3204,0.503580095,1.219408621,0.695070827,2.159187081,0.66472168,DB0887710076573_,0.408386853,0.198366005,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,ruxolitinib,DB08877
,925679,DB06655,10022095,42,3646,8,2111,0.00180402,3.039220718,1.406094226,7.508398427,0.008935115,DB0665510022095_,4.717766288,1.11160114,female,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,liraglutide,DB06655
,925950,DB08906,10046571,43,2150,17,1141,0.339913557,1.342240575,0.745754185,2.522059742,0.509066597,DB0890610046571_,0.675176431,0.294340289,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,fluticasone furoate,DB08906
,926064,DB00563,10062262,53,46593,15,15333,0.675016404,1.162757278,0.645492129,2.221741846,0.802945891,DB0056310062262_,0.21946795,0.150794148,NA,10062262,Spinal operation,10042613,Surgical and medical procedures,Surg,methotrexate,DB00563
,926065,DB00635,10062262,45,33008,17,23777,0.020643392,1.906753475,1.069834971,3.554726101,0.063361436,DB0063510062262_,2.758899868,0.645402045,NA,10062262,Spinal operation,10042613,Surgical and medical procedures,Surg,prednisone,DB00635
,926067,DB09029,10000059,85,11259,63,7207,0.398019153,0.863651351,0.61531703,1.217756636,0.567734822,DB0902910000059_,0.566100831,-0.146586121,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,926068,DB09029,10028391,35,11309,19,7251,0.675522145,1.181054867,0.656787276,2.187517698,0.80333437,DB0902910028391_,0.218984251,0.166407994,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,secukinumab,DB09029
,926162,DB01238,10067482,50,5200,46,3456,0.116898668,0.722449838,0.47310952,1.105334789,0.236478353,DB0123810067482_,1.441898604,-0.32510729,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,aripiprazole,DB01238
,926370,DB00019,10012587,467,18545,160,9369,1.78420743676378e-05,1.474543972,1.22735751,1.778892808,0.000180515,DB0001910012587_,8.619694645,0.388348771,NA,10012587,Device leakage,10077536,Product issues,Prod,pegfilgrastim,DB00019
,926376,DB00019,10057362,545,18467,219,9310,0.005085164,1.254543724,1.068317593,1.477348094,0.020734281,DB0001910057362_,3.875966861,0.22677194,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,926417,DB00563,10065154,337,46309,82,15266,0.012467489,1.354777349,1.060569691,1.747669781,0.042441895,DB0056310065154_,3.15961932,0.303637122,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,methotrexate,DB00563
,926418,DB00688,10065154,65,6425,24,5354,0.000549146,2.256675299,1.39141079,3.775078583,0.003333942,DB0068810065154_,5.703599869,0.813892623,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,mycophenolate mofetil,DB00688
,926606,DB00704,10061428,133,4223,208,4986,0.012719357,0.754975518,0.600307459,0.946849367,0.043125224,DB0070410061428_,3.143647211,-0.281069956,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,naltrexone,DB00704
,927079,DB08932,10014011,93,19350,10,6587,9.40951567529884e-05,3.165879957,1.645494974,6.823611021,0.000756937,DB0893210014011_,7.186230714,1.152431045,female,10014011,Ear infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,927653,DB00404,10076573,81,19811,46,9816,0.451526801,0.872490731,0.599749579,1.282712418,0.619193007,DB0040410076573_,0.47933825,-0.136403249,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,928067,DB00761,10052015,37,15270,37,8588,0.014946471,0.562453711,0.346515712,0.912845077,0.04917304,DB0076110052015_,3.012409773,-0.575446439,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,potassium chloride,DB00761
,928073,DB01075,10052015,30,19918,52,11045,3.81836499275799e-07,0.319929701,0.196923719,0.511269847,6.06439418940446e-06,DB0107510052015_,12.01307591,-1.139653992,male,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,diphenhydramine,DB01075
,928076,DB09153,10052015,24,7775,42,5657,0.000626546,0.41578955,0.240538672,0.703556183,0.003735686,DB0915310052015_,5.589823803,-0.877576036,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,sodium chloride,DB09153
,928085,DB09035,10034474,21,4705,34,6656,0.68203339,0.873801461,0.481250924,1.55168509,0.807715596,DB0903510034474_,0.213545267,-0.134902091,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,nivolumab,DB09035
,928148,DB09029,10042209,90,11254,28,7242,0.000593885,2.068328001,1.33867598,3.2873982,0.003566024,DB0902910042209_,5.636304006,0.726740552,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,secukinumab,DB09029
,928395,DB01175,10054112,91,10633,57,4835,0.061656582,0.725950087,0.514739169,1.031326822,0.146485584,DB0117510054112_,1.920828255,-0.320274018,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,escitalopram,DB01175
,928923,DB09029,10008469,44,11300,21,7249,0.308720734,1.344083706,0.781549819,2.381897809,0.476034641,DB0902910008469_,0.742264653,0.295712521,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,928924,DB09029,10008479,55,11289,34,7236,0.91359695,1.036876917,0.663380692,1.641770207,0.961305652,DB0902910008479_,0.039462865,0.036213231,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,929529,DB00480,10000159,31,67397,20,67642,0.125649253,1.555620575,0.858782992,2.880074529,0.249570455,DB0048010000159_,1.38801402,0.44187455,NA,10000159,Abnormal loss of weight,10027433,Metabolism and nutrition disorders,Metab,lenalidomide,DB00480
,929655,DB06643,10065154,84,52337,14,7501,0.543774574,0.859939224,0.484800876,1.641094824,0.698926086,DB0664310065154_,0.358210284,-0.150893562,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,denosumab,DB06643
,929999,DB00669,10057362,57,6320,8,1089,0.725241933,1.2276778,0.580652114,2.988309703,0.838929024,DB0066910057362_,0.175629172,0.205124417,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,sumatriptan,DB00669
,930407,DB00065,10076573,46,9418,22,4935,0.798629603,1.095618931,0.644987963,1.91475563,0.891257487,DB0006510076573_,0.115121907,0.091319438,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,infliximab,DB00065
,930452,DB09045,10022093,56,2293,19,1705,0.002941496,2.19115763,1.276596157,3.920386862,0.013291823,DB0904510022093_,4.320606245,0.784430002,NA,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,dulaglutide,DB09045
,930530,DB00695,10024119,32,28017,33,20495,0.169016945,0.709368699,0.422165275,1.190585982,0.309524866,DB0069510024119_,1.172716849,-0.343379861,NA,10024119,Left ventricular failure,10007541,Cardiac disorders,Card,furosemide,DB00695
,930578,DB06262,10013578,25,3775,32,4282,0.690995775,0.886195966,0.502506786,1.546455201,0.813673682,DB0626210013578_,0.206195875,-0.120817172,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,931186,DB00007,10069217,7,1940,69,4383,1.34842689634707e-05,0.229218565,0.08869866,0.49930629,0.000141237,DB0000710069217_,8.86507191,-1.473079298,male,10069217,Needle issue,10077536,Product issues,Prod,leuprolide,DB00007
,931194,DB00916,10066901,36,5287,25,2406,0.126476282,0.655347043,0.381697468,1.14170246,0.250777284,DB0091610066901_,1.383190047,-0.422590347,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,metronidazole,DB00916
,931299,DB08912,10047513,33,1297,21,1513,0.037920731,1.832723342,1.023438622,3.351121532,0.101482959,DB0891210047513_,2.287864382,0.605803026,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,dabrafenib,DB08912
,931468,DB06262,10043414,50,3750,48,4266,0.416713586,1.18497273,0.779286667,1.80358691,0.585936452,DB0626210043414_,0.53454394,0.169719762,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,931497,DB09292,10028596,50,4479,125,8137,0.066827492,0.726697365,0.511598992,1.018704528,0.155626883,DB0929210028596_,1.860293913,-0.319245167,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,sacubitril,DB09292
,931512,DB09292,10005851,12,4517,42,8220,0.045691903,0.519964571,0.248913345,1.00729689,0.116886781,DB0929210005851_,2.146549492,-0.653994603,NA,10005851,Blood urea increased,10022891,Investigations,Inv,sacubitril,DB09292
,931513,DB09292,10020646,54,4475,133,8129,0.064409643,0.737557842,0.526160103,1.021541711,0.151385735,DB0929210020646_,1.887924165,-0.304410764,NA,10020646,Hyperkalaemia,10027433,Metabolism and nutrition disorders,Metab,sacubitril,DB09292
,931734,DB09292,10061822,34,4495,45,8217,0.158220797,1.381092089,0.856568916,2.208391771,0.295078306,DB0929210061822_,1.220514515,0.322874555,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,931735,DB09292,10025482,218,4311,256,8006,1.48219337230209e-06,1.581448968,1.308791869,1.909397208,2.03656313596238e-05,DB0929210025482_,10.80166182,0.458341495,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,931986,DB00959,10058854,32,8046,27,4975,0.282551961,0.73285842,0.424769256,1.27315444,0.446660971,DB0095910058854_,0.805955426,-0.310802747,NA,10058854,Cytomegalovirus viraemia,10021881,Infections and infestations,Infec,methylprednisolone,DB00959
,931987,DB01015,10058854,16,9871,56,9325,6.31183870596917e-07,0.269898952,0.144404122,0.477719945,9.52939002793795e-06,DB0101510058854_,11.56112985,-1.309707643,male,10058854,Cytomegalovirus viraemia,10021881,Infections and infestations,Infec,sulfamethoxazole,DB01015
,932074,DB00190,10060904,33,3264,45,4629,0.908192278,1.040032606,0.641431084,1.670609202,0.958977786,DB0019010060904_,0.041887368,0.039252064,NA,10060904,Freezing phenomenon,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,932298,DB06228,10064595,34,15878,65,16011,0.002388683,0.52747169,0.337522512,0.811108893,0.011246021,DB0622810064595_,4.487740868,-0.639660083,NA,10064595,Haemorrhagic arteriovenous malformation,10010331,"Congenital, familial and genetic disorders",Cong,rivaroxaban,DB06228
,932312,DB00211,10033425,36,1400,15,1616,0.000614972,2.769405833,1.471500477,5.467811864,0.003674178,DB0021110033425_,5.606425839,1.018632796,female,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,midodrine,DB00211
,932696,DB00864,10061259,37,6832,15,8377,0.000209522,3.024272788,1.618594923,5.936612534,0.001498578,DB0086410061259_,6.503238846,1.106670662,female,10061259,Klebsiella infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,932859,DB09292,10042674,43,4486,52,8210,0.052092549,1.513395454,0.984614679,2.315417092,0.128958354,DB0929210042674_,2.048265766,0.414355771,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,933560,DB09292,10003119,22,4507,40,8222,1,1.003350394,0.56721189,1.731833674,1,DB0929210003119_,0,0.003344794,NA,10003119,Arrhythmia,10007541,Cardiac disorders,Card,sacubitril,DB09292
,933562,DB09292,10024855,41,4488,80,8182,0.774929196,0.934330191,0.623873275,1.380670854,0.877323349,DB0929210024855_,0.130879655,-0.06792538,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,934007,DB06605,10047942,90,13983,89,12944,0.707604127,0.936126896,0.689799788,1.27050424,0.82522782,DB0660510047942_,0.192095786,-0.066004239,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,apixaban,DB06605
,934036,DB09292,10005725,55,4474,125,8137,0.182457847,0.800229883,0.570579443,1.109927125,0.326997205,DB0929210005725_,1.117803654,-0.222856238,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,sacubitril,DB09292
,934038,DB09292,10062237,41,4488,125,8137,0.003230656,0.594705129,0.40654112,0.854235691,0.014368492,DB0929210062237_,4.242717552,-0.519689578,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,sacubitril,DB09292
,934093,DB00126,10076573,51,10120,19,5926,0.106177364,1.571759722,0.911072155,2.821878017,0.220474149,DB0012610076573_,1.511974827,0.452195834,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,ascorbic acid,DB00126
,934169,DB06262,10008190,34,3766,59,4255,0.047424342,0.651133405,0.412940842,1.012130387,0.120256653,DB0626210008190_,2.118127046,-0.429040735,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,droxidopa,DB06262
,934258,DB04951,10013911,21,1861,33,3024,0.889016824,1.034065613,0.566720677,1.847619176,0.953943796,DB0495110013911_,0.047150524,0.033498229,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,pirfenidone,DB04951
,934302,DB09292,10037087,129,4400,133,8129,4.2432017471673e-06,1.791941764,1.39133525,2.307051898,5.11216891652917e-05,DB0929210037087_,9.881301705,0.583299816,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,sacubitril,DB09292
,934555,DB00704,10053762,95,4261,112,5082,0.943861471,1.011646704,0.759018904,1.346084641,0.982647738,DB0070410053762_,0.017504578,0.011579403,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,naltrexone,DB00704
,934873,DB00620,10076308,49,4779,28,3104,0.640233421,1.136653137,0.698660072,1.882580777,0.777245709,DB0062010076308_,0.25199875,0.128088099,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,triamcinolone,DB00620
,934876,DB00924,10076308,74,10088,32,4219,0.914896807,0.967134015,0.629679752,1.515959275,0.961903265,DB0092410076308_,0.03884139,-0.033418204,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,934877,DB01060,10076308,32,8555,23,5058,0.486673916,0.822606394,0.465966869,1.473881041,0.650589898,DB0106010076308_,0.429875792,-0.195277451,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,amoxicillin,DB01060
,934880,DB01156,10076308,90,13532,26,6302,0.035103704,1.612041074,1.030935718,2.602126306,0.095626579,DB0115610076308_,2.347304479,0.477501124,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,935312,DB00788,10076308,42,9314,15,5046,0.210217823,1.516901126,0.823149583,2.947827434,0.3614322,DB0078810076308_,1.017680806,0.416669521,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,935335,DB09292,10033371,69,4460,74,8188,0.001510592,1.711832129,1.212345667,2.414218935,0.007739942,DB0929210033371_,4.861361103,0.537564217,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,935442,DB11093,10053762,85,1572,13,647,0.000356834,2.690170917,1.478801328,5.296237468,0.002330861,DB1109310053762_,6.061517359,0.98960473,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium citrate,DB11093
,935720,DB01104,10076308,82,15381,35,7251,0.691416153,1.104475406,0.734227212,1.692756591,0.81394991,DB0110410076308_,0.205856451,0.099370476,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,936057,DB01611,10076573,88,11825,20,2341,0.602434376,0.871105997,0.530173809,1.498045437,0.746381968,DB0161110076573_,0.292517788,-0.137991613,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxychloroquine,DB01611
,936108,DB06605,10005724,72,14001,29,13004,8.56852804614584e-05,2.305777595,1.478176626,3.684039539,0.000699236,DB0660510005724_,7.26552294,0.835417971,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,apixaban,DB06605
,936375,DB00704,10012374,38,4318,49,5145,0.746601528,0.924022915,0.587360026,1.443889591,0.855579246,DB0070410012374_,0.155976559,-0.079018408,NA,10012374,Depressed mood,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,936379,DB00704,10042458,48,4308,55,5139,0.843040215,1.041087723,0.69031088,1.565399554,0.920332761,DB0070410042458_,0.083019977,0.040266054,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,937048,DB01168,10017412,40,641,36,795,0.193432673,1.37774603,0.845084023,2.253208129,0.340970244,DB0116810017412_,1.075960066,0.320448853,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,procarbazine,DB01168
,937056,DB01168,10037844,27,654,35,796,0.896480133,0.938947987,0.540459254,1.615436908,0.956301489,DB0116810037844_,0.044682051,-0.062995193,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,procarbazine,DB01168
,937268,DB00668,10019974,46,10045,12,4291,0.15034539,1.637464216,0.85256855,3.399118006,0.284426988,DB0066810019974_,1.257278692,0.493148835,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,epinephrine,DB00668
,937681,DB01136,10040984,32,9852,30,11085,0.5247663,1.200149265,0.705666071,2.046064881,0.682930175,DB0113610040984_,0.381362658,0.182445937,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,carvedilol,DB01136
,937686,DB09292,10003239,49,4480,92,8170,0.929527581,0.971298643,0.670965835,1.391251948,0.970974544,DB0929210003239_,0.029455027,-0.029121296,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,sacubitril,DB09292
,939166,DB00005,10076869,45,128037,10,42409,0.278783098,1.490472342,0.740442917,3.317072884,0.442634475,DB0000510076869_,0.815010962,0.399093078,NA,10076869,Product preparation error,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,939529,DB06273,10042609,52,5043,6,1404,0.036523204,2.412665703,1.033712005,6.88728681,0.098619593,DB0627310042609_,2.316485324,0.880732237,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,tocilizumab,DB06273
,942235,DB00190,10013781,41,3256,21,4653,0.000129439,2.789703752,1.607325183,4.979115426,0.00099395,DB0019010013781_,6.913823176,1.025935408,female,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,carbidopa,DB00190
,942805,DB00203,10076573,27,13851,37,8901,0.002943145,0.468952122,0.274425235,0.791959962,0.013294476,DB0020310076573_,4.320406684,-0.757254601,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,942807,DB00421,10076573,36,8867,22,5230,0.892391182,0.965146972,0.551967291,1.724200697,0.955096839,DB0042110076573_,0.045942542,-0.035474887,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,spironolactone,DB00421
,942809,DB00761,10076573,34,15273,22,8603,0.676217349,0.87053623,0.49423375,1.563399618,0.803815626,DB0076110076573_,0.218385357,-0.138645901,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,942811,DB06403,10076573,39,21432,20,6641,0.089876868,0.604246898,0.343689349,1.094262302,0.195031245,DB0640310076573_,1.634595504,-0.503772393,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,ambrisentan,DB06403
,944277,DB06262,10010264,132,3668,145,4169,0.806530866,1.034693731,0.807550523,1.32473336,0.895426234,DB0626210010264_,0.110455435,0.034105471,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,droxidopa,DB06262
,944624,DB00343,10076573,33,8703,21,5074,0.778240767,0.91617742,0.513847624,1.668211994,0.879072925,DB0034310076573_,0.128887421,-0.087545243,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,944637,DB00190,10050256,26,3271,60,4614,0.036542051,0.611287446,0.36938729,0.986100061,0.098650215,DB0019010050256_,2.316174871,-0.492187978,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,946062,DB00287,10030041,64,1337,25,792,0.092292449,1.516200736,0.932535546,2.53482214,0.198885593,DB0028710030041_,1.615025531,0.41620769,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,travoprost,DB00287
,946091,DB08932,10011878,47,19396,18,6579,0.668924201,0.885689745,0.50436302,1.621480413,0.798928849,DB0893210011878_,0.224483387,-0.121388565,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,macitentan,DB08932
,946171,DB08931,10069339,76,6501,45,2401,0.017372787,0.623789587,0.424531761,0.925917231,0.055345109,DB0893110069339_,2.894166994,-0.471942167,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,riociguat,DB08931
,947612,DB09029,10052904,63,11281,69,7201,0.002238002,0.582861127,0.406986869,0.833409993,0.010657828,DB0902910052904_,4.541460666,-0.539806325,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,secukinumab,DB09029
,947966,DB00207,10005750,45,9035,26,5429,0.902969044,1.039993965,0.627146733,1.758151495,0.957326661,DB0020710005750_,0.043610607,0.039214911,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,azithromycin,DB00207
,947991,DB00190,10061920,28,3269,49,4625,0.416440422,0.808481874,0.488155754,1.315227243,0.58568566,DB0019010061920_,0.53497205,-0.212597019,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,948088,DB09029,10047895,78,11266,62,7208,0.223438412,0.804929363,0.568451233,1.143931675,0.377787126,DB0902910047895_,0.973424401,-0.217000753,NA,10047895,Weight decreased,10022891,Investigations,Inv,secukinumab,DB09029
,948459,DB01281,10017944,43,8889,11,1787,0.465246587,0.785883543,0.397546789,1.693257018,0.632071665,DB0128110017944_,0.458752497,-0.240946662,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,abatacept,DB01281
,948793,DB06605,10017413,74,13999,60,12973,0.488298156,1.142934988,0.801381415,1.63578887,0.651866072,DB0660510017413_,0.427916149,0.133599504,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,apixaban,DB06605
,948812,DB09045,10019211,49,2300,28,1696,0.297296103,1.290354892,0.791354245,2.141753912,0.463192545,DB0904510019211_,0.769612448,0.254917291,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,dulaglutide,DB09045
,948831,DB06605,10028997,43,14030,44,12989,0.668251244,0.90476465,0.579840388,1.410880519,0.798462803,DB0660510028997_,0.225066897,-0.100080424,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,apixaban,DB06605
,949442,DB00921,10076869,90,5755,67,4836,0.468706947,1.128749402,0.811593037,1.576438227,0.635136587,DB0092110076869_,0.453915206,0.121110296,NA,10076869,Product preparation error,10022117,"Injury, poisoning and procedural complications",Inj&P,buprenorphine,DB00921
,949539,DB00635,10013722,42,33011,62,23732,0.000305484,0.487004633,0.320999954,0.732462489,0.002048148,DB0063510013722_,6.190819496,-0.719481643,NA,10013722,Drug level increased,10022891,Investigations,Inv,prednisone,DB00635
,949658,DB00273,10076573,83,8398,19,2174,0.712439005,1.130845009,0.678934702,1.97655505,0.829007891,DB0027310076573_,0.187525605,0.122965149,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,topiramate,DB00273
,950420,DB00281,10012218,50,11408,40,5631,0.024670926,0.617005566,0.39847791,0.960951189,0.0727847,DB0028110012218_,2.620249516,-0.482877235,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,lidocaine,DB00281
,951109,DB09029,10074170,54,11290,39,7231,0.594835612,0.886824266,0.575983521,1.376620356,0.74054655,DB0902910074170_,0.300366784,-0.120108438,NA,10074170,Candida infection,10021881,Infections and infestations,Infec,secukinumab,DB09029
,951349,DB09052,10063620,36,893,55,1004,0.164049926,0.736019381,0.464884403,1.152882478,0.302814094,DB0905210063620_,1.194636214,-0.306498828,NA,10063620,Acute lymphocytic leukaemia recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,blinatumomab,DB09052
,951793,DB00588,10037162,47,16477,7,8461,0.000769037,3.447677008,1.547730629,9.044501974,0.004425647,DB0058810037162_,5.420338692,1.237700673,female,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone propionate,DB00588
,951879,DB05332,10053762,139,890,129,658,0.095048234,0.796745364,0.60916651,1.042533898,0.203299115,DB0533210053762_,1.593076914,-0.227220144,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,romiplostim,DB05332
,952034,DB09029,10064265,37,11307,32,7238,0.218200528,0.740182379,0.448170057,1.228492042,0.371391625,DB0902910064265_,0.99049818,-0.300858665,NA,10064265,Skin haemorrhage,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,952577,DB00788,10076573,68,9288,23,5038,0.060367183,1.603628594,0.985247912,2.699959,0.144113073,DB0078810076573_,1.937157059,0.472268933,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,952636,DB00193,10076573,83,19237,18,8684,0.003442209,2.081509118,1.238599964,3.685490492,0.015123854,DB0019310076573_,4.19148203,0.733093168,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,952855,DB01098,10076573,53,8096,47,7162,1,0.997566533,0.659880129,1.512198276,1,DB0109810076573_,0,-0.002436433,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,rosuvastatin,DB01098
,954211,DB06605,10061105,31,14042,22,13011,0.409309864,1.305616343,0.731536496,2.367990154,0.578689712,DB0660510061105_,0.546988848,0.266675223,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,apixaban,DB06605
,954842,DB00003,10074549,37,2961,40,2553,0.357851001,0.797578704,0.494333231,1.283838965,0.527573815,DB0000310074549_,0.639466489,-0.226174761,NA,10074549,Cystic fibrosis respiratory infection suppression,10042613,Surgical and medical procedures,Surg,dornase alfa,DB00003
,955461,DB08895,10062556,65,28049,24,6622,0.077715326,0.639412205,0.394526692,1.068919326,0.174481942,DB0889510062556_,1.745934028,-0.447205954,NA,10062556,Grip strength decreased,10022891,Investigations,Inv,tofacitinib,DB08895
,956288,DB09029,10033775,51,11293,26,7244,0.412712909,1.25821353,0.769206538,2.104459105,0.582107684,DB0902910033775_,0.541099824,0.229692881,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,secukinumab,DB09029
,958055,DB08868,10024910,42,9160,12,2499,0.868442445,0.954857293,0.492603378,1.995527293,0.941341079,DB0886810024910_,0.060449741,-0.046193382,NA,10024910,Low density lipoprotein increased,10022891,Investigations,Inv,fingolimod,DB08868
,958647,DB09068,10076573,57,2338,16,970,0.193530372,1.477903591,0.831996365,2.771532845,0.341089217,DB0906810076573_,1.075611203,0.390624591,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,vortioxetine,DB09068
,958908,DB09029,10053425,47,11297,13,7257,0.005164901,2.322359628,1.235059373,4.681837257,0.020991018,DB0902910053425_,3.863660641,0.84258375,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,960536,DB09035,10028417,21,4705,45,6645,0.132424297,0.659109869,0.372439284,1.131416773,0.259143966,DB0903510028417_,1.350371518,-0.416865038,NA,10028417,Myasthenia gravis,10029205,Nervous system disorders,Nerv,nivolumab,DB09035
,960638,DB00190,10013983,19,3278,35,4639,0.406630488,0.76827237,0.414371215,1.383155321,0.576211108,DB0019010013983_,0.551281178,-0.26361096,NA,10013983,Dystonia,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,962051,DB00575,10076573,40,5204,27,3802,0.804645732,1.082367599,0.646711242,1.837414714,0.894419007,DB0057510076573_,0.111580926,0.079150863,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,clonidine,DB00575
,964282,DB00370,10076573,38,4503,22,3641,0.241486,1.396566757,0.803559019,2.483712662,0.399575683,DB0037010076573_,0.917352089,0.334016908,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,mirtazapine,DB00370
,965609,DB09292,10012174,38,4491,70,8192,1,0.990222338,0.647816914,1.493093825,1,DB0929210012174_,0,-0.009825777,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,sacubitril,DB09292
,965610,DB09292,10016173,99,4430,159,8103,0.324172166,1.138868013,0.87459395,1.477022863,0.49261294,DB0929210016173_,0.708031525,0.130034798,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,sacubitril,DB09292
,965653,DB00335,10076308,47,8419,20,5445,0.132343486,1.519821513,0.882064279,2.710928269,0.259088261,DB0033510076308_,1.350586501,0.418592902,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,atenolol,DB00335
,967755,DB09029,10061218,56,11288,32,7238,0.66195537,1.122138758,0.713444421,1.792514999,0.793904753,DB0902910061218_,0.230791783,0.11523647,NA,10061218,Inflammation,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,968243,DB08911,10047513,31,1608,27,1721,0.507991228,1.228754884,0.706225541,2.150083806,0.668663901,DB0891110047513_,0.402473736,0.206001367,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,trametinib,DB08911
,969142,DB05676,10037855,38,47091,22,25307,0.78746456,0.9282494,0.535059895,1.648090555,0.884854051,DB0567610037855_,0.122332561,-0.074454833,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,969326,DB09029,10020937,45,11299,38,7232,0.216093954,0.757986426,0.480651952,1.200954612,0.368713378,DB0902910020937_,0.99773569,-0.277089801,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,secukinumab,DB09029
,969578,DB09029,10016173,115,11229,36,7234,0.000103026,2.057861525,1.402535108,3.085248854,0.000818633,DB0902910016173_,7.107874776,0.721667349,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,970396,DB09045,10057362,38,2311,38,1686,0.197261067,0.729621769,0.450807837,1.180857769,0.345688097,DB0904510057362_,1.062218364,-0.315229004,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,dulaglutide,DB09045
,970820,DB00656,10037162,49,11964,12,6607,0.010289957,2.254892914,1.18099584,4.661700573,0.036400177,DB0065610037162_,3.313181654,0.813102483,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,trazodone,DB00656
,970825,DB00864,10028098,16,6853,90,8302,8.78252946774078e-11,0.215387495,0.117973091,0.369543937,2.8802094455342e-09,DB0086410028098_,19.66540282,-1.535316569,male,10028098,Mucormycosis,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,971126,DB01067,10023676,28,4333,30,4793,1,1.032424073,0.593287088,1.791531003,1,DB0106710023676_,0,0.031909506,NA,10023676,Lactic acidosis,10027433,Metabolism and nutrition disorders,Metab,glipizide,DB01067
,971168,DB08820,10036790,32,4369,26,3519,1,0.991320085,0.57115456,1.735363969,1,DB0882010036790_,0,-0.008717805,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ivacaftor,DB08820
,971415,DB09292,10069339,52,4477,128,8134,0.070923296,0.738108668,0.523004312,1.02875993,0.162934828,DB0929210069339_,1.814404984,-0.303664218,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,sacubitril,DB09292
,971898,DB08912,10003239,43,1287,23,1511,0.002510183,2.194382216,1.285369755,3.836873953,0.011696534,DB0891210003239_,4.448462734,0.785900556,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,dabrafenib,DB08912
,984850,DB08895,10037884,62,28052,9,6637,0.22511526,1.629852393,0.804947417,3.732527443,0.37997461,DB0889510037884_,0.967650844,0.488489454,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,985646,DB00028,10076308,99,13359,49,5566,0.320586709,0.84182527,0.5910267,1.212823659,0.488797334,DB0002810076308_,0.715807325,-0.172182804,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,human immunoglobulin g,DB00028
,985658,DB00586,10076308,66,7043,17,2788,0.141136007,1.536836156,0.889290142,2.799515291,0.271459091,DB0058610076308_,1.303943828,0.429725859,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,diclofenac,DB00586
,985879,DB00374,10076309,164,17552,70,5654,0.055607981,0.754710971,0.566161667,1.014950304,0.135376103,DB0037410076309_,1.999698429,-0.281420423,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,990840,DB00864,10022611,26,6843,33,8359,0.896694143,0.962422124,0.552233674,1.661035957,0.956301489,DB0086410022611_,0.044682051,-0.038302126,NA,10022611,Interstitial lung disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tacrolimus,DB00864
,991239,DB00557,10054112,56,5931,20,3047,0.181364086,1.438421572,0.847946975,2.535776216,0.325586636,DB0055710054112_,1.12212669,0.363546382,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,hydroxyzine,DB00557
,991240,DB00567,10054112,54,4465,22,2059,0.709998235,1.131868054,0.67574383,1.957356261,0.827101452,DB0056710054112_,0.189827917,0.123869413,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,cephalexin,DB00567
,992039,DB00814,10076573,57,8230,20,3395,0.615449939,1.175644632,0.694359793,2.06938328,0.756846991,DB0081410076573_,0.278594172,0.16181662,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,meloxicam,DB00814
,992273,DB08895,10037153,167,27947,49,6597,0.192530255,0.804516,0.58122314,1.131384112,0.339846736,DB0889510037153_,1.07926054,-0.217514425,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,tofacitinib,DB08895
,992792,DB01183,10016256,27,532,30,518,0.684091194,0.876421004,0.493790949,1.548845973,0.809059034,DB0118310016256_,0.211883393,-0.131908705,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,naloxone,DB01183
,992850,DB01183,10033295,25,534,37,511,0.116553259,0.646831369,0.367559487,1.12145823,0.2359703,DB0118310033295_,1.44404933,-0.435669654,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,naloxone,DB01183
,994534,DB05676,10040047,41,47088,28,25301,0.376541189,0.786800564,0.474801919,1.32140661,0.546394234,DB0567610040047_,0.604414524,-0.239780475,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,apremilast,DB05676
,995583,DB09107,10003988,52,1163,36,967,0.445080929,1.200913635,0.763075718,1.908121931,0.613107231,DB0910710003988_,0.48921543,0.183082629,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,methoxy polyethylene glycol-epoetin beta,DB09107
,995584,DB09107,10008469,34,1181,21,982,0.337463971,1.346056752,0.753453588,2.457667569,0.506653747,DB0910710008469_,0.679927453,0.297179394,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,methoxy polyethylene glycol-epoetin beta,DB09107
,996682,DB00863,10070608,70,10603,56,5784,0.03918271,0.68186983,0.47223044,0.988528063,0.103984809,DB0086310070608_,2.263510461,-0.382916504,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,ranitidine,DB00863
,997226,DB00715,10037153,48,4795,20,2267,0.696711327,1.134655806,0.658960298,2.023361421,0.817528949,DB0071510037153_,0.201468965,0.126329351,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,paroxetine,DB00715
,997589,DB06273,10069339,23,5072,31,1379,1.07925564040862e-08,0.201787219,0.111961047,0.358790468,2.41021533629061e-07,DB0627310069339_,15.23837956,-1.600541508,male,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,tocilizumab,DB06273
,1000523,DB08895,10006825,62,28052,15,6631,0.885305633,0.977046396,0.548890577,1.850554093,0.952246159,DB0889510006825_,0.048931707,-0.02322114,NA,10006825,C-reactive protein increased,10022891,Investigations,Inv,tofacitinib,DB08895
,1001304,DB08932,10062355,576,18867,166,6431,0.059651814,1.182729348,0.991067478,1.417580331,0.142820029,DB0893210062355_,1.946169982,0.167824775,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,1002995,DB00682,10076573,46,19413,62,16302,0.015475114,0.623053722,0.415713673,0.927798106,0.05050765,DB0068210076573_,2.985630471,-0.473122533,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,1003412,DB06285,10076573,62,8788,12,1094,0.189473873,0.643224958,0.341920501,1.315748419,0.33588405,DB0628510076573_,1.090989267,-0.441260759,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,teriparatide,DB06285
,1004845,DB09076,10035664,73,735,38,572,0.057672899,1.494608349,0.980056722,2.310228974,0.139089105,DB0907610035664_,1.972640512,0.401864199,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,umeclidinium,DB09076
,1006433,DB09073,10053762,205,20055,82,708,3.37323778344288e-49,0.088288687,0.067216272,0.116758633,1.9703456697288e-46,DB0907310053762_,105.2407053,-2.427143304,male,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,palbociclib,DB09073
,1007325,DB00289,10041349,19,464,32,531,0.198561068,0.67973338,0.358826898,1.255416911,0.347331559,DB0028910041349_,1.057475454,-0.386054645,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,atomoxetine,DB00289
,1007897,DB00338,10022081,53,33621,23,22249,0.100590632,1.524910774,0.918256186,2.607752168,0.211742192,DB0033810022081_,1.55238582,0.421935899,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,1008239,DB00924,10076573,38,10124,12,4239,0.440852812,1.325846714,0.67744909,2.789649116,0.609127528,DB0092410076573_,0.495727628,0.282051285,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,1009881,DB09045,10037844,51,2298,35,1689,0.825671572,1.070978245,0.679621491,1.705005804,0.907876062,DB0904510037844_,0.096647405,0.068572479,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dulaglutide,DB09045
,1010570,DB01267,10076573,35,2817,43,3672,0.818862739,1.060969072,0.65728467,1.702158041,0.903336849,DB0126710076573_,0.101659762,0.059182709,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,paliperidone,DB01267
,1011343,DB01192,10069339,28,740,39,515,0.007247835,0.499913836,0.292227287,0.845456418,0.027516333,DB0119210069339_,3.592975507,-0.693319523,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,oxymorphone,DB01192
,1011371,DB09029,10006784,34,11310,21,7249,1,1.037708773,0.584675436,1.88312871,1,DB0902910006784_,0,0.03701518,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,secukinumab,DB09029
,1013516,DB01075,10076573,58,19890,17,11080,0.021219074,1.900534005,1.09078137,3.483460319,0.064801134,DB0107510076573_,2.736432172,0.642134902,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,1015110,DB01240,10028836,63,5688,17,1559,1,1.015730138,0.584972301,1.857178858,1,DB0124010028836_,0,0.015607701,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,epoprostenol,DB01240
,1015281,DB00437,10076308,26,6895,46,11500,0.903062603,0.942709897,0.558847042,1.558948572,0.957326661,DB0043710076308_,0.043610607,-0.058996683,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,allopurinol,DB00437
,1015310,DB00051,10076573,280,25451,92,11328,0.0110261,1.354664463,1.065484705,1.735401376,0.038470967,DB0005110076573_,3.257851421,0.303553795,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,1016407,DB08895,10051076,43,28071,25,6621,0.00057548,0.405703145,0.242040478,0.693672235,0.003470576,DB0889510051076_,5.663434785,-0.902133557,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,1016616,DB00864,10025327,28,6841,32,8360,0.796509415,1.069265165,0.619644746,1.835265849,0.889807667,DB0086410025327_,0.116749944,0.066971651,NA,10025327,Lymphopenia,10005329,Blood and lymphatic system disorders,Blood,tacrolimus,DB00864
,1016746,DB00704,10022061,108,4248,56,5138,1.92274206976627e-07,2.332436327,1.6691843,3.290009736,3.27645220770219e-06,DB0070410022061_,12.62874936,0.846913355,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,1017106,DB06262,10010774,31,3769,27,4287,0.355759495,1.305896469,0.752704917,2.27883117,0.525462931,DB0626210010774_,0.643475631,0.266889754,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,droxidopa,DB06262
,1017806,DB00635,10076573,209,32844,84,23710,3.25175694197193e-06,1.796124534,1.387111075,2.343570956,4.06141274505736e-05,DB0063510076573_,10.11139459,0.585631307,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,1018128,DB09029,10035664,139,11205,89,7181,1,1.000916478,0.760263873,1.323442315,1,DB0902910035664_,0,0.000916058,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,secukinumab,DB09029
,1020192,DB13867,10001053,37,4513,15,2539,0.312912801,1.387678211,0.741704271,2.727220893,0.480441192,DB1386710001053_,0.733050447,0.327631999,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,fluticasone,DB13867
,1020674,DB00181,10003658,34,9822,24,5847,0.586733566,0.843352371,0.485078773,1.488034269,0.733875946,DB0018110003658_,0.309415275,-0.170370411,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,baclofen,DB00181
,1024051,DB00904,10007586,56,23013,46,14410,0.185586597,0.762310506,0.50657954,1.152188303,0.330910323,DB0090410007586_,1.105907867,-0.271401318,NA,10007586,Cardiac murmur,10022891,Investigations,Inv,ondansetron,DB00904
,1024533,DB00295,10061309,50,14613,45,9557,0.140688315,0.726698647,0.475586466,1.113223477,0.270815991,DB0029510061309_,1.306315689,-0.319243403,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,morphine,DB00295
,1026246,DB00355,10019211,55,1738,23,1240,0.035616903,1.705822516,1.024695746,2.92490254,0.096723867,DB0035510019211_,2.335895094,0.534047408,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,aztreonam,DB00355
,1026312,DB00535,10019211,44,1160,20,626,0.594704721,1.187167242,0.678138534,2.146071834,0.740493301,DB0053510019211_,0.300438691,0.171570001,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,cefdinir,DB00535
,1027686,DB00524,10064848,30,1547,22,1322,0.67420647,1.165244126,0.646510017,2.131192919,0.802386899,DB0052410064848_,0.220164369,0.152930616,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,metolazone,DB00524
,1029399,DB00688,10060931,18,6472,64,5314,1.89246161800295e-09,0.230942107,0.128623099,0.39516751,4.95945699194491e-08,DB0068810060931_,16.81938449,-1.46558822,male,10060931,Adenovirus infection,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,1029401,DB01073,10060931,18,1047,32,1618,0.664473767,0.869284819,0.456898871,1.605657887,0.795785584,DB0107310060931_,0.228425496,-0.140084453,NA,10060931,Adenovirus infection,10021881,Infections and infestations,Infec,fludarabine,DB01073
,1029977,DB08895,10066901,757,27357,200,6446,0.156520839,0.891823997,0.760279081,1.05001738,0.29275957,DB0889510066901_,1.228403585,-0.114486479,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,1031295,DB00563,10057668,46,46600,14,15334,0.881826445,1.081181585,0.583841561,2.130189216,0.950574479,DB0056310057668_,0.050688762,0.078054503,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,1033079,DB09029,10042682,44,11300,15,7255,0.032531106,1.883241044,1.027152854,3.646009236,0.090255447,DB0902910042682_,2.405111324,0.632994252,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,1033629,DB00795,10031161,41,4528,16,1487,0.539888631,0.841523411,0.460537465,1.611517135,0.695552748,DB0079510031161_,0.363048429,-0.172541445,NA,10031161,Osteoarthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,sulfasalazine,DB00795
,1033929,DB00996,10019194,41,38912,14,22411,0.093866161,1.686668826,0.90047583,3.350651569,0.201549813,DB0099610019194_,1.601718716,0.522755475,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,1035460,DB09029,10003549,58,11286,41,7229,0.67971721,0.906119204,0.596361939,1.388065648,0.80629196,DB0902910003549_,0.215309369,-0.09858441,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,1037960,DB09029,10019974,62,11282,33,7237,0.401473231,1.20513142,0.776866644,1.900488685,0.571258216,DB0902910019974_,0.559913955,0.186588623,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,secukinumab,DB09029
,1041815,DB00316,10073508,39,65435,27,36926,0.44238996,0.815135869,0.486332623,1.384879663,0.610467266,DB0031610073508_,0.493530605,-0.204400469,NA,10073508,Drug reaction with eosinophilia and systemic symptoms,10040785,Skin and subcutaneous tissue disorders,Skin,acetaminophen,DB00316
,1042261,DB00563,10061924,53,46593,14,15334,0.571059399,1.245886735,0.681228693,2.432246157,0.721440753,DB0056310061924_,0.326505021,0.219847513,NA,10061924,Pulmonary toxicity,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,methotrexate,DB00563
,1043595,DB04951,10022437,34,1848,52,3005,0.822983988,1.063193808,0.666313462,1.676817294,0.906059659,DB0495110022437_,0.098650126,0.061277404,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,pirfenidone,DB04951
,1043596,DB08868,10000496,43,9159,7,2504,0.229748985,1.679316065,0.747788864,4.430545238,0.385641436,DB0886810000496_,0.952847264,0.518386606,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,fingolimod,DB08868
,1044078,DB01137,10054112,73,7699,60,5533,0.479965753,0.874386434,0.611725858,1.253901343,0.644804956,DB0113710054112_,0.438807402,-0.134232856,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,levofloxacin,DB01137
,1045955,DB09292,10005734,98,4431,225,8037,0.059181449,0.790013197,0.614881719,1.00894809,0.141965073,DB0929210005734_,1.952174215,-0.235705629,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,sacubitril,DB09292
,1045975,DB09331,10037844,47,2038,40,2389,0.158006214,1.377258471,0.880205173,2.164214334,0.294782691,DB0933110037844_,1.221516836,0.320094908,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,daratumumab,DB09331
,1046250,DB00210,10040880,64,821,23,326,0.805038367,1.104818601,0.663351197,1.897966285,0.894473299,DB0021010040880_,0.111520227,0.099681159,NA,10040880,Skin irritation,10040785,Skin and subcutaneous tissue disorders,Skin,adapalene,DB00210
,1046500,DB06605,10047340,32,14041,18,13015,0.090884484,1.647835832,0.896965598,3.11965441,0.19664145,DB0660510047340_,1.626373259,0.49946281,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,apixaban,DB06605
,1048021,DB05382,10067482,44,744,47,190,4.32196432849687e-10,0.239506002,0.150132703,0.381301904,1.28003191407933e-08,DB0538210067482_,18.17379573,-1.429176802,male,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,iodine,DB05382
,1048053,DB00210,10053762,45,840,13,336,0.37105031,1.384323567,0.722455584,2.834452993,0.540681932,DB0021010053762_,0.614924099,0.325211621,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,adapalene,DB00210
,1049046,DB08911,10003239,36,1603,21,1727,0.031646194,1.84654932,1.044222316,3.344154252,0.088322384,DB0891110003239_,2.426761704,0.613318665,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,trametinib,DB08911
,1049055,DB00181,10076133,33,9823,21,5850,0.888066746,0.935854885,0.525005436,1.703781357,0.953631242,DB0018110076133_,0.047478221,-0.066294851,NA,10076133,Medical device site pain,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,1049569,DB09302,10025482,41,2157,32,1515,0.719058452,0.899931213,0.550186912,1.483733697,0.83410717,DB0930210025482_,0.181393383,-0.105436949,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1049571,DB09302,10033425,78,2120,45,1502,0.306217572,1.227983686,0.83478625,1.825220927,0.473146336,DB0930210033425_,0.748350561,0.205373544,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,alirocumab,DB09302
,1050574,DB00704,10062355,18,4338,33,5161,0.1590731,0.648967619,0.343525324,1.188460195,0.29625633,DB0070410062355_,1.216530221,-0.432372458,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,1051507,DB00927,10076573,31,7466,19,4997,0.885220992,1.092026851,0.596947784,2.048372528,0.952183569,DB0092710076573_,0.048997438,0.088035465,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,famotidine,DB00927
,1052248,DB01281,10066901,293,8639,57,1741,0.884287945,1.035928794,0.773720909,1.40781695,0.951814769,DB0128110066901_,0.049384833,0.035298409,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,1053261,DB00016,10076573,38,2724,17,2273,0.040126582,1.864964285,1.02425842,3.533743895,0.105929104,DB0001610076573_,2.244985239,0.623241903,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,erythropoietin,DB00016
,1053295,DB01224,10076573,45,8063,26,5891,0.399370999,1.26451555,0.762548665,2.137640568,0.569230632,DB0122410076573_,0.563469598,0.234689084,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,1054456,DB05676,10040880,47,47082,17,25312,0.189618214,1.486340125,0.837558316,2.761709908,0.336026615,DB0567610040880_,1.090564911,0.396316806,NA,10040880,Skin irritation,10040785,Skin and subcutaneous tissue disorders,Skin,apremilast,DB05676
,1054664,DB09292,10013573,360,4169,710,7552,0.21668945,0.918484386,0.802311014,1.050179073,0.369525559,DB0929210013573_,0.99553537,-0.085030374,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,1055074,DB09292,10003549,138,4391,282,7980,0.276290172,0.889336889,0.717700835,1.097883725,0.439725541,DB0929210003549_,0.821604518,-0.117279163,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,1055075,DB09292,10013968,331,4198,575,7687,0.471145522,1.054077636,0.913132265,1.215292676,0.637417926,DB0929210013968_,0.450329754,0.052666106,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sacubitril,DB09292
,1055652,DB00586,10076573,51,7058,17,2788,0.591672062,1.185010939,0.671702255,2.192740355,0.737958203,DB0058610076573_,0.303868091,0.169752005,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,diclofenac,DB00586
,1058194,DB00115,10036495,46,18379,10,10462,0.00331697,2.618404399,1.30270233,5.822291247,0.01467293,DB0011510036495_,4.221750954,0.962565124,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,1060429,DB00343,10048865,35,8701,18,5077,0.775723117,1.134587201,0.624640193,2.130338497,0.877814798,DB0034310048865_,0.130319644,0.126268885,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,diltiazem,DB00343
,1060995,DB05676,10007559,35,47094,27,25302,0.182205147,0.696430237,0.409474587,1.19660402,0.326655683,DB0567610007559_,1.118848621,-0.361787653,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,apremilast,DB05676
,1061373,DB08881,10001760,41,582,43,768,0.309842517,1.257998758,0.788320179,2.005093739,0.477309105,DB0888110001760_,0.739590978,0.229522171,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,vemurafenib,DB08881
,1061908,DB06605,10048865,39,14034,33,13000,0.724566461,1.094712857,0.670454542,1.797371243,0.838350586,DB0660510048865_,0.176318906,0.090492098,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,apixaban,DB06605
,1065875,DB08931,10020937,50,6527,26,2420,0.194092571,0.713043367,0.434354401,1.196210498,0.341812551,DB0893110020937_,1.073492789,-0.338213036,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,1067091,DB00211,10005746,21,1415,35,1596,0.177403093,0.6768355,0.372514608,1.201929466,0.320527928,DB0021110005746_,1.137785866,-0.390327019,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,midodrine,DB00211
,1067469,DB08932,10008111,31,19412,24,6573,0.002947947,0.437376468,0.248254771,0.779414522,0.013311593,DB0893210008111_,4.319119976,-0.826960972,NA,10008111,Cerebral haemorrhage,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,1068359,DB00490,10054112,51,4019,15,1561,0.408286547,1.32048688,0.728324567,2.536590206,0.577693824,DB0049010054112_,0.548711266,0.278000517,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,buspirone,DB00490
,1068456,DB00476,10036495,42,17215,10,6167,0.273405608,1.50450754,0.742282349,3.365027021,0.436376501,DB0047610036495_,0.829249873,0.408465629,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,1070084,DB09303,10013946,80,26151,44,18915,0.171431458,1.315080961,0.898807566,1.9465646,0.312791606,DB0930310013946_,1.162218105,0.273898231,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1071219,DB00956,10076573,43,5771,16,3451,0.107176121,1.607020612,0.885325137,3.061304531,0.221881963,DB0095610076573_,1.505609738,0.474381913,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocodone,DB00956
,1073699,DB00126,10028245,41,10130,20,5925,0.595310994,1.199064406,0.685800158,2.16245923,0.740962241,DB0012610028245_,0.299805612,0.181541591,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,ascorbic acid,DB00126
,1075874,DB08932,10006784,65,19378,15,6582,0.198693162,1.471818496,0.829581171,2.780929897,0.347481688,DB0893210006784_,1.057043313,0.386498708,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,1076124,DB01073,10003997,10,1055,47,1603,0.00051682,0.323398023,0.145064701,0.65208133,0.003172122,DB0107310003997_,5.75335443,-1.128871445,male,10003997,Bacteraemia,10021881,Infections and infestations,Infec,fludarabine,DB01073
,1076657,DB00215,10076573,61,11042,19,5257,0.118885859,1.528467099,0.899652488,2.712321004,0.239567219,DB0021510076573_,1.428921237,0.424265337,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,1076674,DB08932,10074414,203,19240,58,6539,0.28311781,1.189514564,0.883166938,1.623731039,0.447436754,DB0893210074414_,0.804220082,0.173545294,NA,10074414,Catheter management,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,1077310,DB00443,10046571,30,2116,21,1169,0.461652116,0.789298657,0.43485812,1.457546313,0.62887854,DB0044310046571_,0.463817141,-0.236610504,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,betamethasone,DB00443
,1077458,DB09292,10024264,18,4511,41,8221,0.496111221,0.800079317,0.432113145,1.426150809,0.658433903,DB0929210024264_,0.417891137,-0.22304441,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,1078080,DB09292,10036018,24,4505,38,8224,0.595942691,1.152943834,0.660686143,1.975325146,0.741456274,DB0929210036018_,0.299139088,0.142318527,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,sacubitril,DB09292
,1078129,DB01255,10071134,73,2060,59,1519,0.654176581,0.91237331,0.634129978,1.317316846,0.78801281,DB0125510071134_,0.238240934,-0.091706042,NA,10071134,Product physical issue,10077536,Product issues,Prod,lisdexamfetamine,DB01255
,1078613,DB00727,10065154,33,3810,33,4140,0.804901326,1.086589779,0.648635292,1.820399243,0.894427482,DB0072710065154_,0.11157145,0.083044148,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,nitroglycerin,DB00727
,1078830,DB09107,10046735,63,1152,47,956,0.624005086,1.112289964,0.742507182,1.676144019,0.763942865,DB0910710046735_,0.269262277,0.106420921,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,methoxy polyethylene glycol-epoetin beta,DB09107
,1078870,DB00586,10066901,68,7041,34,2771,0.269355659,0.78710406,0.512840507,1.228562785,0.431892485,DB0058610066901_,0.8395786,-0.239394816,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,diclofenac,DB00586
,1078982,DB00563,10074171,31,46615,19,15329,0.047233397,0.536559078,0.293574301,1.005530557,0.119893963,DB0056310074171_,2.121147572,-0.622578605,NA,10074171,Aspergillus infection,10021881,Infections and infestations,Infec,methotrexate,DB00563
,1080351,DB09292,10038435,54,4475,153,8109,0.004238878,0.639574043,0.458996202,0.879650896,0.017905811,DB0929210038435_,4.022630008,-0.446952882,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,sacubitril,DB09292
,1082072,DB01024,10058854,30,2181,24,2096,0.584268951,1.201231702,0.676411971,2.154878647,0.732059512,DB0102410058854_,0.311893468,0.183347449,NA,10058854,Cytomegalovirus viraemia,10021881,Infections and infestations,Infec,mycophenolic acid,DB01024
,1082666,DB09029,10022437,46,11298,35,7235,0.493687057,0.841654082,0.529958702,1.347372322,0.656393146,DB0902910022437_,0.420995361,-0.172386178,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,secukinumab,DB09029
,1083119,DB00381,10013578,33,29327,22,22865,0.589862256,1.16947349,0.661473781,2.106188395,0.736574711,DB0038110013578_,0.305744607,0.156553639,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,1083334,DB09292,10016322,86,4443,162,8100,0.840778676,0.967815556,0.734306492,1.268229113,0.918684216,DB0929210016322_,0.084812833,-0.032713751,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,1083652,DB05676,10003983,58,47071,33,25296,0.826082975,0.944524208,0.60558826,1.495643698,0.908208703,DB0567610003983_,0.096281078,-0.057073961,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,apremilast,DB05676
,1084273,DB00019,10057668,46,18966,14,9515,0.102015665,1.648374334,0.889851595,3.248467744,0.213979313,DB0001910057668_,1.541875939,0.49978955,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,pegfilgrastim,DB00019
,1084789,DB00684,10040753,37,2755,18,2330,0.057026171,1.738271386,0.961885103,3.252674409,0.137826575,DB0068410040753_,1.981759087,0.552891163,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,tobramycin,DB00684
,1084909,DB01413,10001551,21,1199,40,1619,0.238876749,0.708986082,0.394937918,1.238829453,0.396593945,DB0141310001551_,0.92484233,-0.343919383,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,cefepime,DB01413
,1084989,DB09292,10005750,33,4496,65,8197,0.75159025,0.925611666,0.58864163,1.43075433,0.859740615,DB0929210005750_,0.151124545,-0.077300499,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,sacubitril,DB09292
,1084992,DB09292,10042727,29,4500,42,8220,0.383692513,1.261220837,0.756567974,2.076257904,0.5537146,DB0929210042727_,0.591105888,0.23208017,NA,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,sacubitril,DB09292
,1084993,DB09292,10046735,30,4499,43,8219,0.326913051,1.27449378,0.770832275,2.082475933,0.495339936,DB0929210046735_,0.702511013,0.242549065,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,sacubitril,DB09292
,1085250,DB01168,10047942,34,647,29,802,0.156082135,1.45290505,0.849055743,2.500792513,0.292260339,DB0116810047942_,1.230110303,0.373565035,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,procarbazine,DB01168
,1085296,DB08895,10050256,48,28066,11,6635,1,1.031600202,0.5279411,2.204096368,1,DB0889510050256_,0,0.031111191,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,tofacitinib,DB08895
,1085622,DB09292,10000087,32,4497,29,8233,0.006916839,2.020098604,1.181928003,3.46614973,0.02654729,DB0929210000087_,3.628827609,0.703146324,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,sacubitril,DB09292
,1086158,DB06605,10035226,59,14014,60,12973,0.646136184,0.910292436,0.624051318,1.327385643,0.781649463,DB0660510035226_,0.246348896,-0.093989372,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,apixaban,DB06605
,1086581,DB09292,10000059,49,4480,57,8205,0.024389179,1.574431069,1.050341728,2.352107989,0.072147832,DB0929210000059_,2.629038046,0.453893981,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,sacubitril,DB09292
,1086582,DB09292,10028813,104,4425,123,8139,0.001232379,1.555206457,1.182917477,2.041351223,0.006537737,DB0929210028813_,5.030164122,0.441608306,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,sacubitril,DB09292
,1086641,DB00047,10068945,43,9242,23,8495,0.036035132,1.718396588,1.011823052,2.990097746,0.097612557,DB0004710068945_,2.326749141,0.54139164,NA,10068945,Incorrect dose administered by device,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,1091011,DB06403,10013969,41,21430,14,6647,0.751487629,0.908353979,0.484723404,1.805390957,0.859679345,DB0640310013969_,0.151195814,-0.096121132,NA,10013969,Dyspnoea at rest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ambrisentan,DB06403
,1094449,DB00471,10064848,54,14135,30,5435,0.112741907,0.692125855,0.434520295,1.121640463,0.230194774,DB0047110064848_,1.468829483,-0.367987468,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,montelukast,DB00471
,1097881,DB06317,10012735,43,560,40,680,0.256050852,1.305082994,0.815787454,2.092057107,0.41681406,DB0631710012735_,0.875115055,0.266266635,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,elotuzumab,DB06317
,1098405,DB09078,10025482,21,772,30,1026,0.886265096,0.930331254,0.502072014,1.694692113,0.952702357,DB0907810025482_,0.048452746,-0.072214569,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,lenvatinib,DB09078
,1098592,DB05829,10005395,265,1341,25,184,0.107785582,1.454138906,0.931685731,2.353756364,0.222740204,DB0582910005395_,1.501749189,0.374413908,NA,10005395,Blood calcium decreased,10022891,Investigations,Inv,parathyroid hormone,DB05829
,1098970,DB00410,10054112,39,1566,13,996,0.04421096,1.907612474,0.990842939,3.915263208,0.114013744,DB0041010054112_,2.171436274,0.645852447,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,mupirocin,DB00410
,1099817,DB00028,10065464,86,13372,24,5591,0.092638856,1.498247881,0.942546747,2.4666975,0.199444043,DB0002810065464_,1.612221567,0.404296346,NA,10065464,Infusion site haemorrhage,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,1099826,DB01075,10065484,43,19905,9,11088,0.005411147,2.661362793,1.2790495,6.211523904,0.021786323,DB0107510065484_,3.826472881,0.97883832,NA,10065484,Infusion site nodule,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,1099833,DB01073,10014625,37,1028,66,1584,0.537502127,0.863886692,0.556949594,1.322329167,0.693666057,DB0107310014625_,0.36576462,-0.146313662,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,fludarabine,DB01073
,1099956,DB09035,10067584,28,4698,52,6638,0.256792083,0.760832944,0.461929852,1.229198536,0.41767768,DB0903510067584_,0.873045244,-0.273341467,NA,10067584,Type 1 diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,nivolumab,DB09035
,1101190,DB09029,10040882,40,11304,38,7232,0.082141776,0.673480095,0.420639174,1.079910478,0.181895247,DB0902910040882_,1.704324326,-0.395296839,NA,10040882,Skin lesion,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,1101211,DB09038,10023379,23,2225,33,2508,0.420255962,0.785658295,0.439043833,1.383766672,0.58918996,DB0903810023379_,0.529006634,-0.241233321,NA,10023379,Ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,empagliflozin,DB09038
,1101297,DB00924,10048010,51,10111,12,4239,0.07237536,1.781734479,0.935933378,3.675291755,0.165417708,DB0092410048010_,1.799281441,0.577587316,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,cyclobenzaprine,DB00924
,1101301,DB01076,10048010,59,25688,33,25550,0.008752402,1.77824378,1.141901167,2.812415773,0.032010142,DB0107610048010_,3.441702482,0.575626237,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,1101369,DB00184,10069889,61,1233,34,948,0.16865176,1.379226963,0.883961439,2.183514448,0.309083736,DB0018410069889_,1.174143048,0.321523171,NA,10069889,Product adhesion issue,10077536,Product issues,Prod,nicotine,DB00184
,1102526,DB09035,10038435,24,4702,30,6660,0.679043351,1.133119894,0.633099741,2.007794059,0.805741582,DB0903510038435_,0.215992206,0.124974796,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,nivolumab,DB09035
,1103037,DB00091,10076573,47,5463,11,2659,0.024670371,2.079499439,1.060861333,4.453530511,0.0727847,DB0009110076573_,2.620249516,0.73212721,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclosporine,DB00091
,1103902,DB08932,10041807,59,19384,23,6574,0.610839168,0.870005631,0.52864793,1.477391465,0.752932427,DB0893210041807_,0.283779794,-0.139255595,NA,10041807,Sputum discoloured,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,1104098,DB09029,10067723,68,11276,45,7225,0.923007831,0.968213357,0.653909366,1.445885401,0.966306952,DB0902910067723_,0.03427374,-0.032302805,NA,10067723,Skin plaque,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,1104981,DB09029,10023230,35,11309,27,7243,0.514910723,0.830245055,0.487789446,1.42747595,0.674781421,DB0902910023230_,0.393366461,-0.186034375,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,secukinumab,DB09029
,1105485,DB04951,10061822,23,1859,34,3023,0.784137464,1.100014676,0.616624508,1.92950108,0.882643652,DB0495110061822_,0.124833725,0.095323521,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,pirfenidone,DB04951
,1106347,DB00207,10065154,30,9050,32,5423,0.025213749,0.561822372,0.329345134,0.955841348,0.073972316,DB0020710065154_,2.60406437,-0.576569543,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,azithromycin,DB00207
,1106349,DB00706,10065154,12,1063,88,15837,0.034881374,2.031488584,1.008041514,3.745221032,0.095193575,DB0070610065154_,2.351842829,0.708768817,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,tamsulosin,DB00706
,1107040,DB09035,10020772,27,4699,33,6657,0.600329382,1.159086533,0.669428348,1.990770684,0.74476261,DB0903510020772_,0.294689756,0.147632223,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,nivolumab,DB09035
,1107576,DB09292,10019211,82,4447,82,8180,0.000140436,1.839419642,1.334554427,2.534954888,0.001066094,DB0929210019211_,6.843753795,0.60945011,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,1107683,DB00704,10061623,21,4335,34,5160,0.280741127,0.735216826,0.404850857,1.306022069,0.444628718,DB0070410061623_,0.810515688,-0.307589822,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,1107953,DB09029,10030963,49,11295,23,7247,0.228434239,1.366888745,0.816202857,2.352867233,0.383949482,DB0902910030963_,0.957244293,0.312537168,NA,10030963,Oral candidiasis,10021881,Infections and infestations,Infec,secukinumab,DB09029
,1108288,DB00316,10076869,51,65423,14,36939,0.013929943,2.056807129,1.121203863,4.024798183,0.04637727,DB0031610076869_,3.070945818,0.721154843,NA,10076869,Product preparation error,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,1108334,DB00285,10007625,39,10912,20,3698,0.134783643,0.660861999,0.375609848,1.197556224,0.262312162,DB0028510007625_,1.338220028,-0.414210236,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,venlafaxine,DB00285
,1108804,DB09045,10011906,40,2309,41,1683,0.140012976,0.711180835,0.446169359,1.132740477,0.269842069,DB0904510011906_,1.309918419,-0.340828542,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,dulaglutide,DB09045
,1111209,DB01373,10020765,34,22686,23,7358,0.008235771,0.479459789,0.274117086,0.853064814,0.030489754,DB0137310020765_,3.490364596,-0.735095249,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,calcium,DB01373
,1111277,DB00820,10076065,46,11869,6,5810,0.000569224,3.752450886,1.597446196,10.75711216,0.003438367,DB0082010076065_,5.672758593,1.322409196,female,10076065,Infusion site discharge,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,1111595,DB06605,10054236,45,14028,20,13013,0.005897365,2.087067378,1.206680905,3.733241851,0.023351806,DB0660510054236_,3.757080943,0.735759912,NA,10054236,Clostridium difficile infection,10021881,Infections and infestations,Infec,apixaban,DB06605
,1111800,DB09292,10041349,42,4487,67,8195,0.48345352,1.144880508,0.757963652,1.712043511,0.647668295,DB0929210041349_,0.434376605,0.135300272,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,1111834,DB08895,10003481,49,28065,8,6638,0.400814035,1.448678402,0.679993829,3.543782886,0.570682285,DB0889510003481_,0.560922643,0.370651694,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,tofacitinib,DB08895
,1111860,DB09292,10047700,59,4470,52,8210,0.000133499,2.083851627,1.408116504,3.091543746,0.00101962,DB0929210047700_,6.888325285,0.734217925,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,sacubitril,DB09292
,1112904,DB00737,10047571,48,2753,7,925,0.039957881,2.303688449,1.03151448,6.055656736,0.10559422,DB0073710047571_,2.248151641,0.834511512,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,meclizine,DB00737
,1112979,DB01276,10012587,30,1987,45,1466,0.002991108,0.491957523,0.297708748,0.802597393,0.013477547,DB0127610012587_,4.306730179,-0.709362901,NA,10012587,Device leakage,10077536,Product issues,Prod,exenatide,DB01276
,1113088,DB09302,10012735,78,2120,53,1494,0.85723004,1.037124821,0.717504383,1.509038111,0.931519401,DB0930210012735_,0.070938262,0.036452289,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,alirocumab,DB09302
,1113089,DB09302,10022004,92,2106,70,1477,0.625219354,0.921768247,0.663124699,1.286003966,0.764847263,DB0930210022004_,0.268079121,-0.081461446,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1118859,DB00864,10065110,24,6845,39,8353,0.310526186,0.750972868,0.431536373,1.282003672,0.477935403,DB0086410065110_,0.738279697,-0.286385755,NA,10065110,Epstein-Barr viraemia,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,1119176,DB09035,10043778,26,4700,30,6660,0.497011142,1.228054289,0.696652455,2.151483322,0.659145684,DB0903510043778_,0.416810701,0.205431038,NA,10043778,Thyroiditis,10014698,Endocrine disorders,Endo,nivolumab,DB09035
,1119237,DB00927,10076308,49,7448,12,5004,0.000924651,2.743198643,1.436221636,5.672837557,0.005165115,DB0092710076308_,5.265827932,1.009124628,female,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,famotidine,DB00927
,1120605,DB09029,10023232,87,11257,47,7223,0.374698878,1.187679368,0.822546912,1.733859178,0.544536523,DB0902910023232_,0.607820262,0.172001292,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,secukinumab,DB09029
,1122372,DB09029,10042674,73,11271,42,7228,0.63206547,1.114642236,0.751445574,1.672337986,0.77078294,DB0902910042674_,0.260348475,0.108533489,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,1123177,DB09292,10011224,249,4280,378,7884,0.02317566,1.213382447,1.025323104,1.434037955,0.06930287,DB0929210011224_,2.669268957,0.19341187,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sacubitril,DB09292
,1123353,DB09303,10006002,142,26089,67,18892,0.003877102,1.534721497,1.139236396,2.085324519,0.016628805,DB0930310006002_,4.096618824,0.428348929,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1123354,DB09303,10008531,128,26103,71,18888,0.083786134,1.304500921,0.967954108,1.770023422,0.184730821,DB0930310008531_,1.688855535,0.265820532,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1123356,DB09303,10013950,77,26154,40,18919,0.091899965,1.392474702,0.937992511,2.095660117,0.19825924,DB0930310013950_,1.618179814,0.331082525,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1123357,DB09303,10017577,326,25905,193,18766,0.028316644,1.223619301,1.019899383,1.471223138,0.080968506,DB0930310017577_,2.513695015,0.201813107,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1123360,DB09303,10028300,58,26173,29,18930,0.127418552,1.446515978,0.910714714,2.344263011,0.251970857,DB0930310028300_,1.378441844,0.369157891,NA,10028300,Muscle disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1123361,DB09303,10048334,261,25970,145,18814,0.011458818,1.304003947,1.059423314,1.610162278,0.039701448,DB0930310048334_,3.226367618,0.265439491,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1123362,DB09303,10052251,88,26143,66,18893,0.87013054,0.963552829,0.691937825,1.347394988,0.942295438,DB0930310052251_,0.059436426,-0.037127963,NA,10052251,Respiratory tract congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1123363,DB09303,10068319,493,25738,283,18676,0.001803274,1.26405826,1.088567594,1.470051968,0.008933103,DB0930310068319_,4.71799142,0.234327387,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1124015,DB01373,10061309,99,22621,17,7364,0.012535381,1.895650939,1.12523454,3.386542776,0.042636079,DB0137310061309_,3.155054466,0.639562283,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,calcium,DB01373
,1124294,DB01156,10007625,60,13562,27,6301,1,1.032426261,0.644689539,1.693483668,1,DB0115610007625_,0,0.031911626,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,bupropion,DB01156
,1124877,DB06643,10076573,284,52137,32,7483,0.232370281,1.273785666,0.881252453,1.899535652,0.388812327,DB0664310076573_,0.944658502,0.241993306,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,1124986,DB01098,10037162,44,8105,25,7184,0.089965583,1.559955786,0.932903592,2.662803682,0.195135154,DB0109810037162_,1.634062864,0.444657479,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,rosuvastatin,DB01098
,1126082,DB09292,10002424,111,4418,169,8093,0.146051933,1.203118219,0.935538123,1.542328521,0.278509509,DB0929210002424_,1.278303078,0.184916703,NA,10002424,Angioedema,10040785,Skin and subcutaneous tissue disorders,Skin,sacubitril,DB09292
,1126312,DB00355,10054112,104,1689,86,1177,0.255061097,0.842768844,0.62088747,1.146308841,0.415741791,DB0035510054112_,0.877690905,-0.171062565,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,aztreonam,DB00355
,1126491,DB09073,10021097,90,20170,7,783,0.09661824,0.499137117,0.231510558,1.28118275,0.205706354,DB0907310021097_,1.581305591,-0.694874438,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,palbociclib,DB09073
,1126868,DB09292,10035664,41,4488,84,8178,0.573855699,0.889398848,0.595678101,1.309425689,0.723703829,DB0929210035664_,0.323373046,-0.117209496,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,sacubitril,DB09292
,1126871,DB09292,10073085,22,4507,67,8195,0.034685688,0.59707033,0.350639527,0.980637394,0.094821976,DB0929210073085_,2.355754082,-0.515720368,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,sacubitril,DB09292
,1126987,DB01104,10044066,33,15430,20,7266,0.378647027,0.777024034,0.432489602,1.429951606,0.548662465,DB0110410044066_,0.600271845,-0.252283997,NA,10044066,Torsade de pointes,10007541,Cardiac disorders,Card,sertraline,DB01104
,1127034,DB01006,10047899,107,5840,8,169,0.017789972,0.387144173,0.185413192,0.934770972,0.056375841,DB0100610047899_,2.875714567,-0.948958114,NA,10047899,Weight increased,10022891,Investigations,Inv,letrozole,DB01006
,1127047,DB00921,10050895,45,5800,62,4841,0.011075019,0.60583445,0.402489252,0.90564422,0.038600659,DB0092110050895_,3.254485932,-0.501148515,NA,10050895,Drug screen negative,10022891,Investigations,Inv,buprenorphine,DB00921
,1127068,DB00669,10003046,45,6332,6,1091,0.692689528,1.2922044,0.547761988,3.715366719,0.814915421,DB0066910003046_,0.204670949,0.256349597,NA,10003046,Application site irritation,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,1127069,DB00669,10003051,122,6255,12,1085,0.063912682,1.763405848,0.969317457,3.519098896,0.150499659,DB0066910003051_,1.893794458,0.56724708,NA,10003051,Application site pain,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,1127072,DB00669,10065059,93,6284,6,1091,0.014034035,2.690798314,1.186345217,7.540027108,0.046679481,DB0066910065059_,3.064450582,0.989837921,NA,10065059,Application site burn,10018065,General disorders and administration site conditions,Genrl,sumatriptan,DB00669
,1127293,DB00559,10076309,67,9592,53,3253,1.14788139074604e-05,0.428749735,0.293879832,0.628245875,0.000122402,DB0055910076309_,9.008200864,-0.846881899,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,bosentan,DB00559
,1127589,DB00003,10012735,46,2952,49,2544,0.350478137,0.809059748,0.52710559,1.239975116,0.520161364,DB0000310012735_,0.6536162,-0.211882511,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dornase alfa,DB00003
,1128082,DB01254,10073085,97,3370,67,3081,0.082060425,1.3235474,0.955574994,1.842335709,0.18179934,DB0125410073085_,1.704851725,0.280315556,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,dasatinib,DB01254
,1128089,DB05259,10069326,176,11094,55,2673,0.094493942,0.771027092,0.564798687,1.066868075,0.202476013,DB0525910069326_,1.597133852,-0.260031767,NA,10069326,Product substitution issue,10077536,Product issues,Prod,glatiramer,DB05259
,1128778,DB09045,10000087,132,2217,26,1698,1.72394724509504e-12,3.88726051,2.524471922,6.199836742,7.44682881467924e-11,DB0904510000087_,23.32064774,1.35770467,female,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,dulaglutide,DB09045
,1128805,DB09292,10061024,66,4463,105,8157,0.3770935,1.14881663,0.829409991,1.581550776,0.547014495,DB0929210061024_,0.603279978,0.138732395,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,sacubitril,DB09292
,1129007,DB09303,10013700,124,26107,63,18896,0.021433429,1.42459142,1.043046759,1.962373889,0.065306888,DB0930310013700_,2.72865776,0.35388505,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,evolocumab,DB09303
,1129008,DB09303,10020642,125,26106,83,18876,0.573661239,1.088952542,0.817934682,1.456091757,0.723493303,DB0930310020642_,0.32366399,0.085216263,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1129010,DB09303,10040829,39,26192,31,18928,0.717085498,0.909160009,0.552563357,1.507612794,0.832737296,DB0930310040829_,0.183037058,-0.095234173,NA,10040829,Skin discolouration,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1129139,DB09128,10016256,33,1331,20,550,0.220701449,0.681962532,0.37609182,1.265937136,0.374363551,DB0912810016256_,0.982527893,-0.382780561,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,brexpiprazole,DB09128
,1129141,DB09128,10038743,43,1321,27,543,0.108162456,0.654792839,0.390962413,1.114064774,0.223299572,DB0912810038743_,1.499241035,-0.42343637,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,brexpiprazole,DB09128
,1129354,DB08820,10016256,84,4317,48,3497,0.063377512,1.417529986,0.979750093,2.071343398,0.149620138,DB0882010016256_,1.899655613,0.34891591,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ivacaftor,DB08820
,1129855,DB00005,10072878,210,127872,69,42350,1,1.007972216,0.764336339,1.343293778,1,DB0000510072878_,0,0.007940606,NA,10072878,Device use error,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,1130199,DB00996,10013954,34,38919,23,22402,0.582854469,0.850904318,0.486677186,1.513258163,0.730980223,DB0099610013954_,0.313368874,-0.161455592,NA,10013954,Dysphoria,10037175,Psychiatric disorders,Psych,gabapentin,DB00996
,1130444,DB09302,10037844,100,2098,59,1488,0.285504313,1.202053386,0.856417039,1.699704866,0.450138311,DB0930210037844_,0.798200385,0.18403125,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,alirocumab,DB09302
,1130454,DB09302,10022052,82,2116,28,1519,0.000537114,2.101915889,1.34608927,3.371072458,0.00327375,DB0930210022052_,5.721819075,0.742849257,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1131093,DB00051,10073753,97,25634,21,11399,0.001837675,2.053976998,1.270940936,3.469415677,0.0090753,DB0005110073753_,4.702198882,0.719777913,NA,10073753,Fear of injection,10037175,Psychiatric disorders,Psych,adalimumab,DB00051
,1131275,DB09302,10028411,176,2022,147,1400,0.110803628,0.82902382,0.654941444,1.05044454,0.227279516,DB0930210028411_,1.481574669,-0.187506391,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,alirocumab,DB09302
,1131551,DB01225,10065154,38,5006,45,4595,0.270546209,0.775137754,0.488777908,1.223440092,0.433220324,DB0122510065154_,0.83650885,-0.254714518,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,enoxaparin,DB01225
,1131574,DB00660,10063746,56,1201,18,349,0.672270974,0.904106535,0.515479429,1.656642909,0.801035624,DB0066010063746_,0.221849859,-0.100808077,NA,10063746,Accidental death,10018065,General disorders and administration site conditions,Genrl,metaxalone,DB00660
,1132769,DB09292,10011906,218,4311,543,7719,4.73193938737286e-05,0.718870174,0.608763994,0.846621568,0.000421552,DB0929210011906_,7.771566541,-0.330074502,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,1134324,DB01076,10061309,52,25695,38,25545,0.170064037,1.36041958,0.877978416,2.12532556,0.310944157,DB0107610061309_,1.168141941,0.307793167,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,atorvastatin,DB01076
,1134665,DB09029,10014011,64,11280,32,7238,0.294246602,1.283305084,0.826120241,2.029821459,0.460056283,DB0902910014011_,0.776406444,0.249438847,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,secukinumab,DB09029
,1136833,DB05676,10034839,47,47082,12,25317,0.019624965,2.106054767,1.09973367,4.362388342,0.060895077,DB0567610034839_,2.798602948,0.744816419,NA,10034839,Pharyngitis streptococcal,10021881,Infections and infestations,Infec,apremilast,DB05676
,1136907,DB09107,10019211,67,1148,42,961,0.167266946,1.335212862,0.885362682,2.033397316,0.307219039,DB0910710019211_,1.180194304,0.289090727,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,methoxy polyethylene glycol-epoetin beta,DB09107
,1136930,DB09128,10002855,59,1305,38,532,0.039142315,0.633111549,0.408551105,0.991167924,0.103914328,DB0912810002855_,2.264188492,-0.457108649,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,brexpiprazole,DB09128
,1136945,DB00864,10042254,30,6839,37,8355,1,0.990543318,0.590311203,1.649703694,1,DB0086410042254_,0,-0.00950168,NA,10042254,Strongyloidiasis,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,1137486,DB09303,10016256,1026,25205,720,18239,0.552837281,1.031170031,0.934708221,1.137983762,0.706536098,DB0930310016256_,0.347380985,0.03069411,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1137487,DB09303,10019211,889,25342,443,18516,4.62336136893764e-11,1.466223475,1.304683533,1.649562713,1.59691266205684e-09,DB0930310019211_,20.25519366,0.382690031,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1137488,DB09303,10025482,550,25681,283,18676,2.3281137154835e-06,1.413332957,1.220738582,1.639116541,3.02344214483615e-05,DB0930310025482_,10.4065295,0.345950714,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1137489,DB09303,10040753,218,26013,111,18848,0.002428629,1.422999091,1.126241178,1.806439886,0.011399375,DB0930310040753_,4.474196715,0.35276668,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,evolocumab,DB09303
,1137490,DB09303,10049848,74,26157,53,18906,1,1.009177594,0.69936538,1.465042854,1,DB0930310049848_,0,0.009135735,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1138570,DB09303,10005750,214,26017,136,18823,0.253629515,1.138392525,0.913184036,1.423203693,0.414138226,DB0930310005750_,0.881555482,0.129617202,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,evolocumab,DB09303
,1138571,DB09303,10023232,117,26114,67,18892,0.134628612,1.263319407,0.927187036,1.73341622,0.262117186,DB0930310023232_,1.338963599,0.233742707,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1138574,DB09303,10047899,352,25879,148,18811,1.05663127256294e-08,1.728775877,1.42138251,2.111229656,2.36672799312457e-07,DB0930310047899_,15.25658724,0.547413572,NA,10047899,Weight increased,10022891,Investigations,Inv,evolocumab,DB09303
,1138576,DB09303,10013573,654,25577,398,18561,0.006534229,1.19245576,1.049592094,1.356122581,0.025343397,DB0930310013573_,3.675237054,0.176014845,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1138577,DB09303,10016326,42,26189,22,18937,0.254339377,1.380433504,0.805251473,2.428981181,0.41495317,DB0930310016326_,0.87958961,0.322397583,NA,10016326,Feeling cold,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138581,DB09303,10053762,748,25483,631,18328,0.003939144,0.852589398,0.764531056,0.95101545,0.01686465,DB0930310053762_,4.082535582,-0.15947721,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,1138582,DB09303,10003988,1595,24636,1234,17725,0.064403504,0.929956208,0.860639174,1.005017778,0.151383511,DB0930310003988_,1.887938854,-0.072617782,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1138583,DB09303,10028411,1390,24841,1200,17759,3.90412137722363e-06,0.828108633,0.764178265,0.897527691,4.75642319352598e-05,DB0930310028411_,9.953429509,-0.188610934,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1138585,DB09303,10039101,1181,25050,835,18124,0.62783989,1.023317357,0.933767712,1.121793358,0.767178259,DB0930310039101_,0.265036095,0.02304966,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1138586,DB09303,10047571,125,26106,75,18884,0.222180916,1.205585839,0.897737315,1.628443447,0.376290295,DB0930310047571_,0.977394371,0.186965622,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,evolocumab,DB09303
,1138723,DB09303,10003239,971,25260,791,18168,0.011198813,0.882914443,0.801391785,0.97294317,0.038970121,DB0930310003239_,3.244960066,-0.124526977,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1138728,DB09303,10028391,239,25992,216,18743,0.016994749,0.797901223,0.660341855,0.964528389,0.054376992,DB0930310028391_,2.911814157,-0.22577047,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1138731,DB09303,10028836,160,26071,86,18873,0.027504331,1.346795479,1.029209599,1.772592236,0.079106176,DB0930310028836_,2.536964333,0.297728052,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1138734,DB09303,10033425,1083,25148,612,18347,5.82841519855199e-07,1.291028679,1.165936824,1.430501741,8.87343721366575e-06,DB0930310033425_,11.63244833,0.255439326,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1138736,DB09303,10022004,933,25298,727,18232,0.122257013,0.924903392,0.836943514,1.022405778,0.244681584,DB0930310022004_,1.407797571,-0.078065988,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138737,DB09303,10033371,905,25326,513,18446,7.17969310805384e-06,1.284884631,1.149728758,1.437096866,8.12215336110158e-05,DB0930310033371_,9.418330154,0.250668933,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138738,DB09303,10042682,128,26103,52,18907,0.000350796,1.782919744,1.281364084,2.512350808,0.002297988,DB0930310042682_,6.075721378,0.578252326,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138739,DB09303,10046735,227,26004,115,18844,0.001692029,1.430398926,1.137047611,1.807644948,0.008472234,DB0930310046735_,4.770961029,0.357953375,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1138740,DB09303,10016825,69,26162,55,18904,0.586007674,0.906505782,0.626513139,1.317051254,0.733294218,DB0930310016825_,0.310208269,-0.09815787,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,evolocumab,DB09303
,1138741,DB09303,10037844,465,25766,329,18630,0.771790847,1.02193521,0.884295234,1.182008254,0.875098025,DB0930310037844_,0.13341937,0.021698095,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1138743,DB09303,10012735,736,25495,424,18535,0.000162762,1.261964304,1.116580388,1.427694556,0.001209383,DB0930310012735_,6.717645359,0.232669479,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1138744,DB09303,10028735,179,26052,169,18790,0.014028785,0.763940233,0.615067906,0.949126917,0.046670877,DB0930310028735_,3.064634921,-0.269265722,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1138747,DB09303,10000059,224,26007,126,18833,0.025670531,1.287372055,1.029488838,1.615746098,0.074980542,DB0930310000059_,2.590526639,0.252602974,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1138752,DB09303,10013774,35,26196,24,18935,0.895506585,1.054119937,0.609217886,1.852949013,0.95615204,DB0930310013774_,0.044838341,0.052706236,NA,10013774,Dry eye,10015919,Eye disorders,Eye,evolocumab,DB09303
,1138755,DB09303,10022062,93,26138,36,18923,0.001216894,1.870209417,1.259647797,2.831017509,0.006472293,DB0930310022062_,5.040224861,0.626050412,NA,10022062,Injection site extravasation,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138758,DB09303,10022067,808,25423,539,18420,0.145070133,1.086158377,0.971118463,1.215517984,0.277170157,DB0930310022067_,1.283123675,0.082647046,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138761,DB09303,10022086,2958,23273,1276,17683,4.27921515699191e-62,1.761345116,1.644017141,1.887730442,3.94663755794851e-59,DB0930310022086_,134.4796565,0.566077788,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138764,DB09303,10022107,125,26106,70,18889,0.094300567,1.292045863,0.956104627,1.757962357,0.202244493,DB0930310022107_,1.598277954,0.256226903,NA,10022107,Injection site urticaria,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138767,DB09303,10037660,138,26093,122,18837,0.114978294,0.816604215,0.634930067,1.051311381,0.233591317,DB0930310037660_,1.454182198,-0.202600738,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138770,DB09303,10043521,125,26106,59,18900,0.006905629,1.533822171,1.116072623,2.128856377,0.026515882,DB0930310043521_,3.630011417,0.427762771,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1138771,DB09303,10000060,119,26112,52,18907,0.002367259,1.656991614,1.18600382,2.342910373,0.011162149,DB0930310000060_,4.495226789,0.505003677,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1138772,DB09303,10022094,146,26085,63,18896,0.000545336,1.678747291,1.240338609,2.294551186,0.003316555,DB0930310022094_,5.708828781,0.518047855,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138773,DB09303,10028813,755,25476,333,18626,7.42392976292655e-15,1.657619864,1.453087091,1.89404484,4.45520533832248e-13,DB0930310028813_,28.43953306,0.505382757,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1138774,DB09303,10047700,203,26028,92,18867,0.000146148,1.599429102,1.243238151,2.07062327,0.001101818,DB0930310047700_,6.810793871,0.469646754,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1138847,DB09303,10015150,131,26100,89,18870,0.681471215,1.064184085,0.806249676,1.410047688,0.807434868,DB0930310015150_,0.213892886,0.062208388,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1138848,DB09303,10069868,777,25454,521,18438,0.17999343,1.080308649,0.963955466,1.211406948,0.323839099,DB0930310069868_,1.127508495,0.077246786,NA,10069868,Device issue,10077536,Product issues,Prod,evolocumab,DB09303
,1138849,DB09303,10044565,118,26113,51,18908,0.001743306,1.675308081,1.195874456,2.376003609,0.008679384,DB0930310044565_,4.746804732,0.515997077,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1138851,DB09303,10002855,141,26090,71,18888,0.012036662,1.437701876,1.072747277,1.941443501,0.041239416,DB0930310002855_,3.188360787,0.36304592,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,evolocumab,DB09303
,1138853,DB09303,10060933,138,26093,145,18814,0.001653778,0.686245881,0.539146806,0.873091719,0.008319892,DB0930310060933_,4.789105956,-0.376519288,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138854,DB09303,10005734,32,26199,28,18931,0.513251532,0.825819217,0.481464383,1.42403691,0.673249107,DB0930310005734_,0.395639874,-0.191379395,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,evolocumab,DB09303
,1138856,DB09303,10020751,307,25924,175,18784,0.012161028,1.27111219,1.05129446,1.540823951,0.041597063,DB0930310020751_,3.179725715,0.239892257,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,evolocumab,DB09303
,1138857,DB09303,10011224,667,25564,346,18613,2.92777927703413e-07,1.403568647,1.229038221,1.605093207,4.79182305708855e-06,DB0930310011224_,12.24859962,0.339018027,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1138858,DB09303,10013968,510,25721,401,18558,0.209564396,0.91763567,0.80240881,1.049969127,0.360664589,DB0930310013968_,1.01980687,-0.085954841,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1138859,DB09303,10016322,533,25698,313,18646,0.00312828,1.235569043,1.071175269,1.427094666,0.014000776,DB0930310016322_,4.268642499,0.211531628,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138860,DB09303,10019303,64,26167,42,18917,0.693735043,1.101636346,0.73459639,1.667467545,0.815602702,DB0930310019303_,0.203827928,0.096796662,NA,10019303,Heart rate increased,10022891,Investigations,Inv,evolocumab,DB09303
,1138861,DB09303,10020772,184,26047,117,18842,0.291761126,1.137592195,0.896689351,1.448020516,0.457206032,DB0930310020772_,0.782621154,0.128913919,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,evolocumab,DB09303
,1138862,DB09303,10029216,101,26130,32,18927,1.99628583461932e-05,2.286137916,1.521937869,3.519004577,0.000199433,DB0930310029216_,8.52003118,0.826863894,NA,10029216,Nervousness,10037175,Psychiatric disorders,Psych,evolocumab,DB09303
,1138863,DB09303,10062244,128,26103,92,18867,1,1.005621521,0.76275429,1.330166675,1,DB0930310062244_,0,0.005605779,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1138879,DB09303,10013781,72,26159,54,18905,0.856806339,0.96357514,0.667386523,1.398555727,0.931280429,DB0930310013781_,0.071194834,-0.037104808,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1138880,DB09303,10022437,168,26063,114,18845,0.62848655,1.065566201,0.834382259,1.364850355,0.767769948,DB0930310022437_,0.264265138,0.063506302,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,evolocumab,DB09303
,1138883,DB09303,10046306,125,26106,72,18887,0.129010496,1.256023596,0.931838534,1.703822087,0.25416286,DB0930310046306_,1.369780036,0.227950854,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,evolocumab,DB09303
,1138884,DB09303,10022061,570,25661,209,18750,1.11263562132616e-18,1.992721626,1.695735337,2.348955376,1.02436522965178e-16,DB0930310022061_,36.81728836,0.689501356,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138885,DB09303,10053425,504,25727,336,18623,0.258803563,1.085823159,0.94267082,1.251913476,0.419916768,DB0930310053425_,0.867698758,0.082338371,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138888,DB09303,10010774,129,26102,75,18884,0.135945494,1.244360998,0.928365738,1.6780002,0.264008866,DB0930310010774_,1.331772592,0.218622144,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1138890,DB09303,10017944,62,26169,43,18916,0.9212003,1.04223868,0.694767968,1.576219032,0.965093784,DB0930310017944_,0.035529997,0.041370976,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1138896,DB09303,10042209,77,26154,23,18936,9.66901961653872e-05,2.423822597,1.504010279,4.049358725,0.000774022,DB0930310042209_,7.163910037,0.885345879,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,evolocumab,DB09303
,1138922,DB09303,10028334,979,25252,598,18361,0.000967318,1.19036154,1.07216365,1.322416284,0.005359604,DB0930310028334_,5.22886513,0.174257076,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1138923,DB09303,10040984,67,26164,42,18917,0.497477178,1.153349892,0.772353705,1.739850664,0.659595353,DB0930310040984_,0.416128734,0.142670658,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,evolocumab,DB09303
,1138925,DB09303,10061224,95,26136,43,18916,0.011955324,1.598969241,1.103546002,2.350162133,0.041029597,DB0930310061224_,3.193461603,0.469359197,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1138926,DB09303,10057362,578,25653,340,18619,0.002344698,1.23385725,1.075811072,1.41679466,0.011070665,DB0930310057362_,4.503456446,0.210145238,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,1138927,DB09303,10076573,2927,23304,2190,16769,0.195829726,0.961712295,0.906427078,1.020509657,0.344087994,DB0930310076573_,1.066857859,-0.039039942,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,1138928,DB09303,10005423,34,26197,19,18940,0.405506126,1.29375204,0.717058744,2.401762897,0.575121595,DB0930310005423_,0.55317379,0.257546555,NA,10005423,Blood cholesterol abnormal,10022891,Investigations,Inv,evolocumab,DB09303
,1138929,DB09303,10022052,1520,24711,704,18255,1.36049921281843e-24,1.594987495,1.454605617,1.750196484,2.02037976321652e-22,DB0930310022052_,49.95358655,0.466865896,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138930,DB09303,10008479,248,25983,183,18776,0.844557577,0.979290576,0.804982208,1.19312089,0.921485667,DB0930310008479_,0.081768056,-0.020926871,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138931,DB09303,10046571,212,26019,45,18914,6.10033579564451e-17,3.424525902,2.471141576,4.83898596,4.63431579157561e-15,DB0930310046571_,33.00528782,1.230963039,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,evolocumab,DB09303
,1138932,DB09303,10022093,257,25974,103,18856,1.69526702519564e-07,1.811336818,1.434559018,2.30108959,2.9315851156097e-06,DB0930310022093_,12.73996729,0.594065146,NA,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1138933,DB09303,10063829,246,25985,187,18772,0.624709927,0.950370862,0.781847406,1.156723166,0.764450048,DB0930310063829_,0.268598595,-0.050902989,NA,10063829,Device malfunction,10077536,Product issues,Prod,evolocumab,DB09303
,1138934,DB09303,10037087,465,25766,242,18717,2.33590326120327e-05,1.395800242,1.190969662,1.639123345,0.000227996,DB0930310037087_,8.386184193,0.333467901,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1139149,DB11581,10037660,76,1677,84,2676,0.025553044,1.443571861,1.037804449,2.005373747,0.074724566,DB1158110037660_,2.593946385,0.367120501,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,venetoclax,DB11581
,1139652,DB00381,10014380,22,29338,48,22839,3.25117499571794e-05,0.356808719,0.205063911,0.602816118,0.000304714,DB0038110014380_,8.096135833,-1.030555441,male,10014380,Electrocardiogram QRS complex prolonged,10022891,Investigations,Inv,amlodipine,DB00381
,1139932,DB09303,10015967,48,26183,18,18941,0.01722531,1.929051776,1.101311837,3.524853726,0.054954154,DB0930310015967_,2.901256014,0.657028574,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,evolocumab,DB09303
,1140153,DB01017,10029331,30,1439,24,877,0.324700511,0.761918497,0.427502534,1.371459499,0.49316074,DB0101710029331_,0.706920113,-0.271915688,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,minocycline,DB01017
,1140273,DB09303,10013952,177,26054,88,18871,0.00400807,1.456824176,1.121124931,1.9046039,0.017108172,DB0930310013952_,4.068199021,0.376258844,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1140274,DB09303,10028810,709,25522,539,18420,0.382910494,0.949387257,0.846167899,1.065567527,0.552980733,DB0930310028810_,0.592432119,-0.051938495,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,evolocumab,DB09303
,1140275,DB09303,10043528,33,26198,38,18921,0.054015741,0.627220577,0.381049258,1.027496489,0.132506182,DB0930310043528_,2.021125976,-0.466457002,NA,10043528,Throat tightness,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1140276,DB09303,10051572,135,26096,69,18890,0.018879255,1.416247085,1.051333098,1.92256507,0.059055243,DB0930310051572_,2.82928195,0.348010475,NA,10051572,Injection site discolouration,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1140277,DB09303,10053156,50,26181,41,18918,0.595304107,0.88120559,0.571149382,1.366462518,0.740962241,DB0930310053156_,0.299805612,-0.126464321,NA,10053156,Musculoskeletal discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1141461,DB09303,10062355,142,26089,110,18849,0.608766466,0.932668692,0.721443743,1.208332808,0.751346507,DB0930310062355_,0.28588834,-0.069705241,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1141896,DB05679,10076573,44,6887,20,4889,0.099810262,1.561695627,0.899967789,2.800714988,0.210491307,DB0567910076573_,1.558310926,0.445772171,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,ustekinumab,DB05679
,1141925,DB09303,10035664,185,26046,105,18854,0.048826448,1.275388092,0.997620913,1.637654069,0.122804936,DB0930310035664_,2.097158071,0.243250518,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,evolocumab,DB09303
,1142166,DB09302,10003988,49,2149,42,1505,0.388680166,0.817097032,0.527001373,1.27173629,0.558598223,DB0930210003988_,0.582324807,-0.201997425,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,alirocumab,DB09302
,1142587,DB09292,10003988,48,4481,73,8189,0.33999176,1.20160753,0.815339182,1.756800534,0.509154707,DB0929210003988_,0.675003366,0.183660269,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,sacubitril,DB09292
,1144854,DB00019,10069216,1395,17617,723,8806,0.457942305,0.96448175,0.877731415,1.060388716,0.625261923,DB0001910069216_,0.46958464,-0.036164369,NA,10069216,Device adhesion issue,10077536,Product issues,Prod,pegfilgrastim,DB00019
,1144884,DB08911,10076309,34,1605,25,1723,0.188423181,1.459815006,0.841490513,2.564595211,0.334540913,DB0891110076309_,1.094996096,0.37830972,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,trametinib,DB08911
,1145036,DB09292,10038428,39,4490,67,8195,0.76050628,1.062404866,0.695696321,1.602846074,0.86692142,DB0929210038428_,0.142806941,0.06053508,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,sacubitril,DB09292
,1145079,DB00502,10010144,37,1357,76,1796,0.032963262,0.644423685,0.420033775,0.973473167,0.091199341,DB0050210010144_,2.394707609,-0.439398873,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,haloperidol,DB00502
,1145153,DB06643,10017412,46,52375,8,7507,0.541022431,0.824160858,0.384986122,2.022583368,0.696396984,DB0664310017412_,0.361835402,-0.193389553,NA,10017412,Full blood count abnormal,10022891,Investigations,Inv,denosumab,DB06643
,1145310,DB00019,10072878,1963,17049,1004,8525,0.578839626,0.977633014,0.901608952,1.060578888,0.727580497,DB0001910072878_,0.318030637,-0.02262092,NA,10072878,Device use error,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,1146096,DB09029,10022061,46,11298,12,7258,0.004241259,2.46247492,1.282605901,5.10993585,0.017912988,DB0902910022061_,4.022229226,0.901166909,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,1147973,DB01060,10042609,45,8542,17,5064,0.115953803,1.569221137,0.87957262,2.927818632,0.235091651,DB0106010042609_,1.447779837,0.450579405,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,amoxicillin,DB01060
,1148017,DB09303,10060800,102,26129,20,18939,1.80275468639045e-09,3.696491209,2.272170418,6.306493051,4.75041673501482e-08,DB0930310060800_,16.8624484,1.307384048,female,10060800,Hot flush,10047065,Vascular disorders,Vasc,evolocumab,DB09303
,1154823,DB00864,10001052,25,6844,64,8328,0.00125266,0.475355433,0.286505367,0.766497999,0.006623652,DB0086410001052_,5.017108383,-0.743692474,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tacrolimus,DB00864
,1160237,DB00999,10061309,57,21373,22,12217,0.128305155,1.480970459,0.890773794,2.54552315,0.253238296,DB0099910061309_,1.373424351,0.392697588,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,hydrochlorothiazide,DB00999
,1162016,DB09038,10013968,25,2223,36,2505,0.36865924,0.78257944,0.448783735,1.344987732,0.53831499,DB0903810013968_,0.619311407,-0.245159841,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,empagliflozin,DB09038
,1162372,DB08931,10075192,38,6539,15,2431,0.876959448,0.941817891,0.505054492,1.84652729,0.947522962,DB0893110075192_,0.053904108,-0.059943344,NA,10075192,Internal haemorrhage,10047065,Vascular disorders,Vasc,riociguat,DB08931
,1162584,DB09029,10010774,67,11277,27,7243,0.043723519,1.593768772,1.004474216,2.59492287,0.11303395,DB0902910010774_,2.180067062,0.466101508,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,1163984,DB00007,10076573,29,1918,287,4165,2.21152584692412e-20,0.219487139,0.143798483,0.323516611,2.37265130148574e-18,DB0000710076573_,40.58252365,-1.516461642,male,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,leuprolide,DB00007
,1167861,DB08906,10010264,45,2148,21,1137,0.696212826,1.134252953,0.658017126,2.014998876,0.817235866,DB0890610010264_,0.201827528,0.125974243,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,fluticasone furoate,DB08906
,1168966,DB00404,10061309,40,19852,14,9848,0.311674482,1.417330314,0.754470763,2.821871447,0.479057585,DB0040410061309_,0.735934471,0.348775042,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,alprazolam,DB00404
,1171080,DB09029,10000060,36,11308,16,7254,0.255732378,1.443330982,0.78012869,2.787871681,0.416462256,DB0902910000060_,0.875959444,0.366953624,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,1171164,DB06643,10069868,102,52319,10,7505,0.316213921,1.46314978,0.763559428,3.144553608,0.483884433,DB0664310069868_,0.725909176,0.380591496,NA,10069868,Device issue,10077536,Product issues,Prod,denosumab,DB06643
,1172293,DB09303,10013496,34,26197,22,18937,0.78673954,1.117191304,0.634492285,2.005843176,0.88430399,DB0930310013496_,0.122954395,0.110817772,NA,10013496,Disturbance in attention,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1172295,DB09303,10016766,86,26145,43,18916,0.049387943,1.446994158,0.991699042,2.139192787,0.123876339,DB0930310016766_,2.088471481,0.369488411,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1174533,DB09303,10023874,45,26186,13,18946,0.002106517,2.504407317,1.327177208,5.061550302,0.010152147,DB0930310023874_,4.590070045,0.918052107,NA,10023874,Laryngitis,10021881,Infections and infestations,Infec,evolocumab,DB09303
,1174597,DB11595,10002034,42,1071,34,1000,0.561065704,1.153325389,0.709948341,1.885576988,0.713574646,DB1159510002034_,0.337468228,0.142649412,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,atezolizumab,DB11595
,1174728,DB00601,10020993,37,868,25,886,0.122287385,1.510341723,0.8767392,2.641685628,0.244714199,DB0060110020993_,1.407664285,0.412335932,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,linezolid,DB00601
,1175894,DB09292,10043417,22,4507,58,8204,0.159338213,0.690469775,0.401843935,1.147357003,0.29661508,DB0929210043417_,1.215320009,-0.37038308,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,1177000,DB00531,10003917,18,7234,32,6484,0.022422642,0.504210851,0.266221624,0.926824167,0.067558362,DB0053110003917_,2.694763433,-0.684760743,NA,10003917,B-cell type acute leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyclophosphamide,DB00531
,1178307,DB00072,10067482,68,3655,8,327,0.404083737,0.760524866,0.360691732,1.848580572,0.573785372,DB0007210067482_,0.555499869,-0.273746471,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,trastuzumab,DB00072
,1178311,DB01075,10067482,47,19901,22,11075,0.532408645,1.188863212,0.701949405,2.072795893,0.689224617,DB0107510067482_,0.372188056,0.172997566,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,1179977,DB09343,10011906,258,1261,408,1475,0.000692005,0.739735646,0.619407098,0.882424864,0.004052887,DB0934310011906_,5.50832585,-0.301462392,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,tipiracil,DB09343
,1181856,DB00451,10062262,60,47211,8,15411,0.011117509,2.448301743,1.165660522,5.930934191,0.038733345,DB0045110062262_,3.251054419,0.895394618,NA,10062262,Spinal operation,10042613,Surgical and medical procedures,Surg,levothyroxine,DB00451
,1181857,DB00497,10062262,51,19216,39,16336,0.672359241,1.111671357,0.717973931,1.733360748,0.80107711,DB0049710062262_,0.22179807,0.10586461,NA,10062262,Spinal operation,10042613,Surgical and medical procedures,Surg,oxycodone,DB00497
,1181867,DB00996,10062262,65,38888,32,22393,0.527073494,1.169687736,0.754560496,1.846725231,0.684729244,DB0099610062262_,0.378731783,0.156736821,NA,10062262,Spinal operation,10042613,Surgical and medical procedures,Surg,gabapentin,DB00996
,1181933,DB09302,10022086,108,2090,38,1509,0.00010432,2.051645365,1.396339866,3.071718185,0.000827415,DB0930210022086_,7.097204478,0.718642088,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1181936,DB09302,10028813,77,2121,40,1507,0.126848821,1.367627163,0.915945585,2.069309328,0.251251543,DB0930210028813_,1.381300677,0.313077241,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,alirocumab,DB09302
,1182773,DB06605,10061818,98,13975,80,12953,0.408820559,1.135409228,0.835568587,1.546638836,0.578204075,DB0660510061818_,0.547828401,0.126993139,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,1185721,DB09292,10030095,28,4501,52,8210,1,0.982175846,0.596338468,1.586655933,1,DB0929210030095_,0,-0.017984917,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,1186421,DB01611,10076308,62,11851,22,2339,0.025728219,0.556245094,0.336376772,0.952308169,0.075094801,DB0161110076308_,2.589003952,-0.586546266,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxychloroquine,DB01611
,1187454,DB09303,10048908,33,26198,17,18942,0.31561678,1.403521786,0.759379023,2.687444067,0.483280151,DB0930310048908_,0.727158771,0.338984639,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,evolocumab,DB09303
,1187455,DB09303,10027175,315,25916,168,18791,0.001360133,1.359502286,1.122688102,1.650934708,0.007095581,DB0930310027175_,4.948283098,0.307118666,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1187456,DB09303,10073317,1798,24433,1187,17772,0.012597387,1.101819363,1.020743655,1.189563165,0.042804926,DB0930310073317_,3.151102082,0.09696278,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,1187481,DB09303,10016807,36,26195,17,18942,0.164460618,1.531286448,0.837842989,2.908147318,0.30338636,DB0930310016807_,1.192748169,0.426108198,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,evolocumab,DB09303
,1187482,DB09303,10024264,78,26153,81,18878,0.024016399,0.695112468,0.50243886,0.961140654,0.071281736,DB0930310024264_,2.641115145,-0.363681622,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1187483,DB09303,10047895,208,26023,165,18794,0.37099103,0.910421639,0.73792535,1.124680123,0.540653632,DB0930310047895_,0.614976442,-0.093847447,NA,10047895,Weight decreased,10022891,Investigations,Inv,evolocumab,DB09303
,1187484,DB09303,10061428,126,26105,58,18901,0.004333482,1.572891083,1.142981654,2.186739554,0.01822781,DB0930310061428_,4.004806821,0.45291538,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,evolocumab,DB09303
,1187521,DB09303,10041349,83,26148,58,18901,0.864705969,1.034421569,0.730378338,1.4735159,0.938004886,DB0930310041349_,0.064000121,0.0338424,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1187523,DB09303,10001760,274,25957,32,18927,6.21397918113081e-34,6.2432344,4.317813348,9.311807162,1.76577775974079e-31,DB0930310001760_,70.81154663,1.831498381,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1187524,DB09303,10028372,284,25947,224,18735,0.342436456,0.915457261,0.764858794,1.096745749,0.511751556,DB0930310028372_,0.669916014,-0.088331599,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1187526,DB09303,10013709,218,26013,144,18815,0.422666528,1.095005251,0.882326888,1.362255434,0.591607097,DB0930310013709_,0.524912551,0.090759159,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1187539,DB09303,10003549,399,25832,346,18613,0.013446249,0.830919932,0.716747202,0.963580994,0.045060836,DB0930310003549_,3.099741795,-0.18522184,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1187541,DB09303,10013911,77,26154,41,18918,0.134715379,1.358440919,0.917877795,2.03669376,0.262218139,DB0930310013911_,1.338578531,0.306337659,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1187592,DB09303,10000081,153,26078,98,18861,0.369538199,1.129119248,0.869910005,1.471475071,0.539179104,DB0930310000081_,0.617707475,0.121437902,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1187594,DB09303,10061623,114,26117,92,18867,0.437041409,0.895155095,0.673709583,1.192074675,0.605600371,DB0930310061623_,0.501534964,-0.110758285,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1187595,DB09303,10027599,93,26138,13,18946,3.48032964310088e-11,5.185269397,2.887421341,10.10471028,1.22627968725076e-09,DB0930310027599_,20.5192809,1.645821797,female,10027599,Migraine,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1187596,DB09303,10037867,37,26194,36,18923,0.235107378,0.742498933,0.456220296,1.209448394,0.392120343,DB0930310037867_,0.93618649,-0.297733845,NA,10037867,Rash macular,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1187599,DB09303,10012587,43,26188,16,18943,0.024151377,1.943955968,1.072538758,3.698288712,0.07158132,DB0930310012587_,2.636921127,0.664725056,NA,10012587,Device leakage,10077536,Product issues,Prod,evolocumab,DB09303
,1188856,DB09053,10076309,80,2205,124,3928,0.336449861,1.149261821,0.852309944,1.542488602,0.505525715,DB0905310076309_,0.682156371,0.139119842,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ibrutinib,DB09053
,1190727,DB08932,10041232,67,19376,9,6588,0.005240016,2.531247081,1.255820332,5.778034154,0.021243745,DB0893210041232_,3.851692793,0.928712099,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,1191594,DB06285,10054112,213,8637,41,1065,0.014661998,0.640631447,0.453756197,0.92387399,0.048421988,DB0628510054112_,3.027801262,-0.445300952,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,teriparatide,DB06285
,1192517,DB08895,10076573,55,28059,13,6633,1,1.000106223,0.539023851,1.996792319,1,DB0889510076573_,0,0.000106217,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,1193140,DB00433,10076308,48,7608,32,5988,0.499435074,1.180584738,0.738331295,1.910844117,0.661226027,DB0043310076308_,0.413659551,0.166009856,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,prochlorperazine,DB00433
,1193151,DB01060,10076573,34,8553,20,5061,1,1.005927372,0.561999102,1.84647202,1,DB0106010076573_,0,0.005909875,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,amoxicillin,DB01060
,1193514,DB01413,10010264,33,1187,25,1634,0.030936066,1.816660001,1.041700646,3.205228228,0.086787395,DB0141310010264_,2.444293888,0.596999651,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,cefepime,DB01413
,1193743,DB09292,10023232,22,4507,48,8214,0.532572191,0.835343422,0.479521341,1.412933367,0.689368431,DB0929210023232_,0.371979417,-0.179912355,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,sacubitril,DB09292
,1193855,DB09037,10025482,42,2484,27,2808,0.028193591,1.758251441,1.055482708,2.975216596,0.080682477,DB0903710025482_,2.517233867,0.564319815,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,pembrolizumab,DB09037
,1193856,DB09037,10076309,141,2385,156,2679,0.904935527,1.015263278,0.797129404,1.292160216,0.957667115,DB0903710076309_,0.043255041,0.015147966,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pembrolizumab,DB09037
,1193991,DB09303,10006784,114,26117,53,18906,0.007457765,1.557042671,1.113929634,2.200844763,0.028164848,DB0930310006784_,3.569680596,0.442788298,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1200395,DB00381,10073085,33,29327,31,22856,0.453059956,0.829636943,0.492381683,1.401112565,0.620647867,DB0038110073085_,0.476991399,-0.186767092,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,1202234,DB01109,10076308,61,4351,33,4237,0.006772883,1.799924387,1.157159043,2.844869339,0.02610532,DB0110910076308_,3.645616143,0.587744657,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,heparin,DB01109
,1202236,DB09153,10076308,80,7719,46,5653,0.205241624,1.273626893,0.873825224,1.875583998,0.355457342,DB0915310076308_,1.034350031,0.241868651,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium chloride,DB09153
,1203151,DB08895,10047340,48,28066,9,6637,0.615194659,1.261207516,0.61166209,2.924982954,0.75658034,DB0889510047340_,0.278946551,0.232069608,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,tofacitinib,DB08895
,1203229,DB09029,10022095,51,11293,13,7257,0.001866375,2.520890627,1.350189925,5.055993497,0.009196301,DB0902910022095_,4.688953957,0.924612263,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,1204235,DB06605,10003445,44,14029,32,13001,0.30364829,1.274230863,0.789407239,2.077363926,0.47021299,DB0660510003445_,0.754569517,0.242342752,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,apixaban,DB06605
,1204242,DB00374,10013969,80,17636,20,5704,0.351098318,1.293693114,0.783946635,2.232116125,0.520831835,DB0037410013969_,0.652328063,0.257501007,NA,10013969,Dyspnoea at rest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,1204245,DB08931,10013969,44,6533,22,2424,0.266587928,0.742104886,0.434298829,1.302976256,0.428775505,DB0893110013969_,0.846821796,-0.29826469,NA,10013969,Dyspnoea at rest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,1204272,DB08931,10033775,50,6527,18,2428,1,1.033332864,0.59107326,1.885974353,1,DB0893110033775_,0,0.032789369,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,riociguat,DB08931
,1204287,DB06605,10048908,33,14040,19,13014,0.097795107,1.609884637,0.888477255,2.998275174,0.207561418,DB0660510048908_,1.572327991,0.476162522,NA,10048908,Seasonal allergy,10021428,Immune system disorders,Immun,apixaban,DB06605
,1206338,DB06791,10022086,70,709,44,494,0.690235558,1.108424349,0.735523408,1.685025627,0.813142777,DB0679110022086_,0.206848567,0.102939501,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,lanreotide,DB06791
,1206874,DB09045,10016256,57,2292,39,1685,0.754991083,1.07447097,0.698881222,1.667032483,0.862429787,DB0904510016256_,0.14800154,0.071828419,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dulaglutide,DB09045
,1207307,DB09029,10017944,45,11299,26,7244,0.716020094,1.109642913,0.669344822,1.875287955,0.831977905,DB0902910017944_,0.183949395,0.104038263,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,1209035,DB00327,10061309,46,6092,33,4229,0.908862726,0.967643165,0.604301022,1.565021964,0.95913476,DB0032710061309_,0.041723693,-0.03289189,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,hydromorphone,DB00327
,1210103,DB09107,10012735,30,1185,24,979,1,1.032690404,0.579398923,1.859128399,1,DB0910710012735_,0,0.032167439,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,methoxy polyethylene glycol-epoetin beta,DB09107
,1210568,DB09292,10005557,30,4499,83,8179,0.048475031,0.657114079,0.417022922,1.010429356,0.122210453,DB0929210005557_,2.102010693,-0.41989764,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,sacubitril,DB09292
,1210767,DB09292,10020642,21,4508,33,8229,0.572377767,1.161609248,0.6378402,2.071297199,0.722394527,DB0929210020642_,0.325183854,0.149806327,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,sacubitril,DB09292
,1210768,DB09292,10033557,33,4496,34,8228,0.0208305,1.776252129,1.064705019,2.959883355,0.063810932,DB0929210033557_,2.75183075,0.574505599,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,sacubitril,DB09292
,1213051,DB08820,10028810,76,4325,87,3458,0.025642943,0.698486803,0.504865965,0.964604443,0.074922731,DB0882010028810_,2.591297951,-0.358838993,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ivacaftor,DB08820
,1213425,DB00668,10076308,85,10006,37,4266,0.921025239,0.979440294,0.657191557,1.485140421,0.965007709,DB0066810076308_,0.035619189,-0.020773999,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,epinephrine,DB00668
,1213432,DB14513,10076308,35,7142,18,3546,0.884691308,0.965443088,0.531288288,1.813399539,0.951944941,DB1451310076308_,0.049248081,-0.035168124,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium,DB14513
,1213616,DB08881,10042496,26,597,39,772,0.609961628,0.862180782,0.49783925,1.471260155,0.75218585,DB0888110042496_,0.284771845,-0.148290307,NA,10042496,Sunburn,10022117,"Injury, poisoning and procedural complications",Inj&P,vemurafenib,DB08881
,1214625,DB09128,10001540,92,1272,47,523,0.247489506,0.804952022,0.551562209,1.187376712,0.406729859,DB0912810001540_,0.899606051,-0.216972603,NA,10001540,Akathisia,10029205,Nervous system disorders,Nerv,brexpiprazole,DB09128
,1215500,DB09292,10076573,124,4405,242,8020,0.579271927,0.932898388,0.742787466,1.166929944,0.728036846,DB0929210076573_,0.317403619,-0.069458993,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,sacubitril,DB09292
,1216088,DB08895,10001551,45,28069,18,6628,0.075464428,0.590342606,0.334709624,1.084333204,0.17058673,DB0889510001551_,1.768511429,-0.527052223,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,tofacitinib,DB08895
,1216491,DB00003,10036790,37,2961,49,2544,0.050080612,0.648817795,0.410156506,1.018524344,0.125159866,DB0000310036790_,2.078163428,-0.432603349,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dornase alfa,DB00003
,1216494,DB11065,10036790,29,3157,48,2640,0.003807026,0.505291045,0.306318663,0.820372842,0.016388416,DB1106510036790_,4.111180542,-0.68262069,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pancrelipase amylase,DB11065
,1217864,DB01015,10076308,32,9855,45,9336,0.087950523,0.673679533,0.413989647,1.084808828,0.191777302,DB0101510076308_,1.651420465,-0.395000751,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sulfamethoxazole,DB01015
,1219053,DB05676,10028164,62,47067,18,25311,0.018863248,1.852287475,1.081318528,3.327914003,0.059022734,DB0567610028164_,2.829832584,0.616421348,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,apremilast,DB05676
,1220138,DB01190,10054112,41,4893,19,2266,1,0.999370019,0.565514686,1.827348296,1,DB0119010054112_,0,-0.000630179,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,clindamycin,DB01190
,1220988,DB09302,10015150,41,2157,18,1529,0.109213307,1.61441496,0.902922017,2.997668707,0.22485973,DB0930210015150_,1.492278493,0.478972637,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,alirocumab,DB09302
,1220990,DB09302,10028334,99,2099,60,1487,0.36626046,1.168847519,0.833564913,1.650532888,0.535854179,DB0930210028334_,0.623893209,0.156018237,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,alirocumab,DB09302
,1220992,DB09302,10033371,75,2123,46,1501,0.511424455,1.152676253,0.783036367,1.71267141,0.671736548,DB0930210033371_,0.397889058,0.142086415,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1221016,DB09302,10019211,70,2128,40,1507,0.325828614,1.239239055,0.82358548,1.887028651,0.494309426,DB0930210019211_,0.70459359,0.214497526,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,alirocumab,DB09302
,1221018,DB09302,10013968,48,2150,21,1526,0.065305508,1.622123524,0.948239419,2.864620776,0.152963401,DB0930210013968_,1.877556596,0.483736108,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alirocumab,DB09302
,1222663,DB09303,10048959,261,25970,141,18818,0.005187381,1.341281119,1.087707708,1.659616736,0.021069351,DB0930310048959_,3.859935842,0.293625216,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1223593,DB09303,10008469,127,26104,92,18867,1,0.997726867,0.756408325,1.320252191,1,DB0930310008469_,0,-0.00227572,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1223834,DB08881,10053762,29,594,46,765,0.405268621,0.812040475,0.485591227,1.338596093,0.574924344,DB0888110053762_,0.553516822,-0.208205094,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,vemurafenib,DB08881
,1224194,DB09145,10022061,53,946,6,462,9.53894999614146e-05,4.310555573,1.835992415,12.36326111,0.000765358,DB0914510022061_,7.175166781,1.461066799,female,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,water,DB09145
,1225187,DB00313,10012218,14,1225,45,1472,0.000835807,0.37397502,0.188659475,0.697743462,0.0047465,DB0031310012218_,5.350347818,-0.983566276,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,valproic acid,DB00313
,1225722,DB09303,10016334,81,26150,44,18915,0.14621428,1.331569976,0.910959516,1.96932219,0.278707883,DB0930310016334_,1.277591061,0.286358679,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1225725,DB09303,10019194,40,26191,28,18931,1,1.03258179,0.621114203,1.738656713,1,DB0930310019194_,0,0.032062258,NA,10019194,Head discomfort,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1225769,DB09303,10060795,64,26167,64,18895,0.072623429,0.722108634,0.502306178,1.0380678,0.1658693,DB0930310060795_,1.796555148,-0.325579689,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,evolocumab,DB09303
,1225772,DB09303,10024910,238,25993,158,18801,0.413679324,1.089562198,0.886474553,1.342087555,0.583032763,DB0930310024910_,0.539511898,0.085775963,NA,10024910,Low density lipoprotein increased,10022891,Investigations,Inv,evolocumab,DB09303
,1225779,DB09303,10013082,49,26182,39,18920,0.666487172,0.907927482,0.583777514,1.420674571,0.797224752,DB0930310013082_,0.226618642,-0.09659077,NA,10013082,Discomfort,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1225790,DB09303,10022000,355,25876,219,18740,0.067161114,1.173946395,0.988103438,1.397245181,0.156272287,DB0930310022000_,1.856155363,0.16037106,NA,10022000,Influenza,10021881,Infections and infestations,Infec,evolocumab,DB09303
,1225823,DB09303,10022095,174,26057,92,18867,0.015021839,1.369419617,1.056877884,1.784058633,0.049376668,DB0930310022095_,3.008277282,0.314387013,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1225828,DB09303,10047513,88,26143,71,18888,0.519812948,0.895481397,0.647219448,1.242723863,0.678971518,DB0930310047513_,0.3871761,-0.110393831,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,evolocumab,DB09303
,1225832,DB09303,10000087,265,25966,139,18820,0.001984276,1.381790555,1.120160791,1.710605954,0.009664015,DB0930310000087_,4.639346085,0.323380162,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1226258,DB09343,10053762,31,1488,24,1859,0.10000484,1.613461622,0.912149789,2.886421224,0.210788659,DB0934310053762_,1.556899261,0.478381947,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,tipiracil,DB09343
,1226259,DB09343,10061818,326,1193,415,1468,0.706968009,0.966620173,0.817455625,1.142494128,0.824750993,DB0934310061818_,0.192673765,-0.033949649,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,tipiracil,DB09343
,1226291,DB09303,10049816,53,26178,48,18911,0.267793767,0.7976607,0.529281034,1.204864991,0.4301622,DB0930310049816_,0.843592931,-0.226071959,NA,10049816,Muscle tightness,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1227059,DB00331,10073085,33,24913,20,20732,0.27317916,1.373078701,0.764616149,2.526074477,0.436140474,DB0033110073085_,0.829790899,0.317055445,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,1227178,DB00313,10007617,51,1188,44,1473,0.092919887,1.436947616,0.933837529,2.218922904,0.199950817,DB0031310007617_,1.609683855,0.362521153,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,valproic acid,DB00313
,1228774,DB09570,10029331,176,3725,191,3744,0.487277046,0.926198717,0.74648397,1.148659448,0.651131245,DB0957010029331_,0.429044052,-0.076666471,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,ixazomib,DB09570
,1229140,DB09035,10001053,22,4704,46,6644,0.139461555,0.675525716,0.386446562,1.147813282,0.269066074,DB0903510001053_,1.312798302,-0.392264053,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,nivolumab,DB09035
,1229266,DB01118,10010144,32,3031,18,4691,0.000665255,2.751060574,1.495287978,5.216076623,0.0039303,DB0111810010144_,5.539039597,1.011986501,female,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,amiodarone,DB01118
,1229527,DB09303,10028596,120,26111,115,18844,0.033756563,0.753079643,0.577825972,0.981878785,0.092900352,DB0930310028596_,2.376227845,-0.283584289,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,evolocumab,DB09303
,1229528,DB09303,10033433,41,26190,15,18944,0.021335999,1.977060746,1.071030824,3.846494959,0.06509015,DB0930310033433_,2.731982048,0.68161127,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1229949,DB09331,10051792,177,1908,197,2232,0.664997147,1.051065748,0.8450934,1.306471996,0.796094552,DB0933110051792_,0.228037317,0.049804647,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,daratumumab,DB09331
,1230044,DB00864,10072358,35,6834,18,8374,0.002226551,2.382491678,1.311908485,4.472551135,0.010615796,DB0086410072358_,4.545412216,0.868146864,NA,10072358,Trichodysplasia spinulosa,10040785,Skin and subcutaneous tissue disorders,Skin,tacrolimus,DB00864
,1235165,DB14500,10076308,41,7768,13,4060,0.149765334,1.64831626,0.864653869,3.35671189,0.283635838,DB1450010076308_,1.260064122,0.499754319,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium,DB14500
,1237877,DB08932,10007625,44,19399,12,6585,0.644317189,1.244633474,0.645682231,2.590503705,0.780474911,DB0893210007625_,0.247852684,0.218841088,NA,10007625,Cardiogenic shock,10007541,Cardiac disorders,Card,macitentan,DB08932
,1237970,DB08931,10076309,45,6532,14,2432,0.659944548,1.196715573,0.643648323,2.365158306,0.792319293,DB0893110076309_,0.23279082,0.179580781,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,riociguat,DB08931
,1237971,DB08932,10076309,48,19395,13,6584,0.556397422,1.253404309,0.667895691,2.523283156,0.709791853,DB0893210076309_,0.342783517,0.225863297,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,1239240,DB00182,10037153,60,5134,22,2830,0.105476041,1.503275173,0.906439993,2.579482706,0.219330893,DB0018210037153_,1.51717376,0.407646177,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,amphetamine,DB00182
,1239411,DB08895,10040808,53,28061,18,6628,0.176016586,0.695485793,0.400571806,1.262502642,0.318690957,DB0889510040808_,1.143533431,-0.363144695,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,tofacitinib,DB08895
,1240094,DB01234,10076308,48,31577,54,32834,0.766380857,0.924302266,0.613033615,1.389869049,0.871350686,DB0123410076308_,0.137710759,-0.078716133,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,1240947,DB11581,10016288,93,1660,157,2603,0.594123747,0.928861687,0.705492952,1.217551235,0.740138045,DB1158110016288_,0.300918562,-0.073795435,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,venetoclax,DB11581
,1242561,DB00563,10071404,16,46630,41,15307,9.37679506197235e-14,0.128083371,0.067112592,0.233373925,4.83272663144987e-12,DB0056310071404_,26.05561029,-2.055073889,male,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,1244220,DB00003,10061428,32,2966,21,2572,0.336396499,1.321321291,0.736667041,2.417523378,0.505484178,DB0000310061428_,0.682238541,0.278632214,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,dornase alfa,DB00003
,1244655,DB09292,10001949,32,4497,47,8215,0.346870213,1.243716762,0.766822931,1.993849601,0.516293415,DB0929210001949_,0.661080042,0.218104285,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,1244656,DB09292,10010305,55,4474,65,8197,0.020944015,1.550281782,1.06038562,2.259240228,0.064102634,DB0929210010305_,2.747269817,0.43843671,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,sacubitril,DB09292
,1245739,DB00804,10054112,39,2961,15,884,0.416467803,0.776278124,0.416063193,1.523320717,0.585690924,DB0080410054112_,0.534963062,-0.253244415,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,dicyclomine,DB00804
,1247161,DB00537,10064848,100,7457,51,4247,0.551854919,1.116735583,0.787499449,1.600450406,0.705761035,DB0053710064848_,0.348478576,0.110409771,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,ciprofloxacin,DB00537
,1247596,DB09083,10013968,37,689,21,277,0.234621628,0.70859476,0.395888899,1.298411903,0.39145801,DB0908310013968_,0.937877024,-0.344471481,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ivabradine,DB09083
,1249145,DB09128,10028813,47,1317,12,558,0.146358934,1.659063791,0.858388765,3.463124759,0.278842068,DB0912810028813_,1.277109724,0.506253462,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,brexpiprazole,DB09128
,1249923,DB00332,10070608,34,2650,20,1636,1,1.049502368,0.584781986,1.931189894,1,DB0033210070608_,0,0.048316116,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,ipratropium,DB00332
,1249924,DB00537,10070608,61,7496,57,4241,0.007012588,0.605468431,0.4141358,0.886447895,0.02683055,DB0053710070608_,3.618214124,-0.501752855,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,ciprofloxacin,DB00537
,1251080,DB09302,10003549,37,2161,38,1509,0.09869199,0.679997813,0.418373368,1.104269358,0.20886871,DB0930210003549_,1.566049406,-0.385665697,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1251081,DB09302,10003239,106,2092,62,1485,0.261790493,1.213547269,0.872201877,1.700484003,0.423469221,DB0930210003239_,0.859274446,0.193547698,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,alirocumab,DB09302
,1251113,DB09302,10016256,74,2124,67,1480,0.138356049,0.769662302,0.541659811,1.095247257,0.267473374,DB0930210016256_,1.318735254,-0.261803429,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1251115,DB09302,10016322,32,2166,22,1525,1,1.024086549,0.574328356,1.857763572,1,DB0930210016322_,0,0.023801043,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1251117,DB09302,10024910,82,2116,42,1505,0.095105595,1.388507148,0.939917758,2.077589979,0.203359335,DB0930210024910_,1.592780739,0.328229176,NA,10024910,Low density lipoprotein increased,10022891,Investigations,Inv,alirocumab,DB09302
,1251120,DB09302,10028810,32,2166,26,1521,0.593155173,0.864302733,0.496758151,1.516727271,0.73928181,DB0930210028810_,0.302076092,-0.145832186,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,alirocumab,DB09302
,1251121,DB09302,10039101,43,2155,31,1516,0.905807969,0.975791894,0.597643773,1.609884819,0.957917651,DB0930210039101_,0.042993464,-0.024505939,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alirocumab,DB09302
,1251362,DB00997,10076573,82,5249,14,3500,8.66710466982449e-08,3.905012251,2.1956109,7.467726217,1.59088579780961e-06,DB0099710076573_,13.35121959,1.362260921,female,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,doxorubicin,DB00997
,1251432,DB09045,10033645,45,2304,63,1661,0.000749957,0.515019817,0.341419988,0.771472767,0.004332446,DB0904510033645_,5.44162305,-0.6635499,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,dulaglutide,DB09045
,1251928,DB00951,10059866,31,621,32,533,0.517589596,0.831600446,0.483675625,1.428117784,0.677161044,DB0095110059866_,0.389846156,-0.184403187,NA,10059866,Drug resistance,10018065,General disorders and administration site conditions,Genrl,isoniazid,DB00951
,1253342,DB00704,10033295,28,4328,114,5080,1.25463977337039e-10,0.28833425,0.183141538,0.440091846,4.0168339151085e-09,DB0070410033295_,19.33277183,-1.243634881,male,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,naltrexone,DB00704
,1253939,DB08820,10046306,22,4379,37,3508,0.005591589,0.476367309,0.267171811,0.830780076,0.022372313,DB0882010046306_,3.79993111,-0.741566065,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,ivacaftor,DB08820
,1254050,DB09570,10002034,43,3858,24,3911,0.0195409,1.816133004,1.075287177,3.135708704,0.060702307,DB0957010002034_,2.801773583,0.596709518,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,ixazomib,DB09570
,1254744,DB08932,10062132,49,19394,13,6584,0.4689913,1.279579737,0.683077736,2.572839784,0.635352986,DB0893210062132_,0.453574551,0.246531693,NA,10062132,Tooth extraction,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,1254998,DB09303,10017885,65,26166,39,18920,0.372431582,1.205113477,0.797704282,1.842107326,0.542136796,DB0930310017885_,0.612236918,0.186573734,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1255003,DB09303,10003246,140,26091,82,18877,0.13401189,1.235248263,0.933288507,1.64387944,0.26133263,DB0930310003246_,1.341961239,0.211271973,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1255006,DB09303,10003983,45,26186,34,18925,0.909257963,0.956506623,0.598934949,1.540456037,0.959216791,DB0930310003983_,0.04163817,-0.044467566,NA,10003983,Back disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1255009,DB09303,10052904,122,26109,117,18842,0.030038837,0.752521086,0.578715803,0.978898293,0.084799789,DB0930310052904_,2.467462225,-0.284326262,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1255012,DB09303,10053459,30,26201,32,18927,0.124575659,0.677246965,0.397417943,1.151276905,0.24793452,DB0930310053459_,1.3945906,-0.389719279,NA,10053459,Secretion discharge,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1255013,DB09303,10006451,147,26084,57,18902,4.51635054877578e-05,1.868822972,1.36671694,2.585623558,0.0004053,DB0930310006451_,7.810883832,0.625308806,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,evolocumab,DB09303
,1255014,DB09303,10033557,108,26123,34,18925,7.9856945286409e-06,2.30115682,1.55150199,3.491988725,8.93398513238247e-05,DB0930310033557_,9.323062906,0.833411962,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,evolocumab,DB09303
,1255034,DB09303,10043417,158,26073,127,18832,0.399307997,0.898587597,0.706332311,1.145045105,0.569156266,DB0930310043417_,0.56360025,-0.106931085,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1255035,DB09303,10041052,29,26202,32,18927,0.118563106,0.654648648,0.38193408,1.117676089,0.239045121,DB0930310041052_,1.431102952,-0.423656602,NA,10041052,Sluggishness,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1255063,DB09303,10022998,25,26206,36,18923,0.008928269,0.501449356,0.288459519,0.859061663,0.032506345,DB0930310022998_,3.426319983,-0.690252661,NA,10022998,Irritability,10037175,Psychiatric disorders,Psych,evolocumab,DB09303
,1255095,DB09303,10022081,328,25903,226,18733,0.603293807,1.049603394,0.88233111,1.25027625,0.746988853,DB0930310022081_,0.291705016,0.048412373,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1255098,DB09303,10010305,96,26135,59,18900,0.369881154,1.176656346,0.841601564,1.657047408,0.539514782,DB0930310010305_,0.617085095,0.162676811,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,evolocumab,DB09303
,1255101,DB09303,10043882,47,26184,31,18928,0.7315593,1.096006818,0.681569567,1.785221695,0.843896963,DB0930310043882_,0.169724874,0.091673409,NA,10043882,Tinnitus,10013993,Ear and labyrinth disorders,Ear,evolocumab,DB09303
,1255334,DB00758,10039020,6,8294,45,10029,5.79851572632071e-07,0.161237738,0.056192117,0.379375229,8.8381551676625e-06,DB0075810039020_,11.63643239,-1.82487537,male,10039020,Rhabdomyolysis,10028395,Musculoskeletal and connective tissue disorders,Musc,clopidogrel,DB00758
,1255597,DB09343,10000087,31,1488,32,1851,0.522877323,1.205007302,0.707524223,2.049803214,0.681286752,DB0934310000087_,0.383771986,0.186485626,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,tipiracil,DB09343
,1255598,DB09343,10016256,226,1293,306,1577,0.275351924,0.900819808,0.743445965,1.090371851,0.438670544,DB0934310016256_,0.824006616,-0.104450032,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,tipiracil,DB09343
,1256181,DB00542,10010144,39,1647,33,1391,1,0.998123871,0.608031117,1.647336565,1,DB0054210010144_,0,-0.001877892,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,benazepril,DB00542
,1256251,DB09292,10007554,84,4445,137,8125,0.43524904,1.120739693,0.841641108,1.485114085,0.603657715,DB0929210007554_,0.504747939,0.113988907,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,sacubitril,DB09292
,1256513,DB01073,10029366,72,993,98,1552,0.417345132,1.148219232,0.826059049,1.590016297,0.586485433,DB0107310029366_,0.533607448,0.138212248,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,fludarabine,DB01073
,1256558,DB01050,10061309,62,18046,13,9358,0.002055716,2.473079925,1.344852273,4.905373911,0.009946524,DB0105010061309_,4.610532121,0.905464307,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ibuprofen,DB01050
,1257154,DB09564,10005555,47,1180,50,897,0.116147643,0.714680987,0.464829232,1.09724511,0.235359589,DB0956410005555_,1.446640769,-0.335919009,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,insulin degludec,DB09564
,1257260,DB01076,10067973,28,25719,35,25548,0.380067821,0.794686336,0.465536268,1.345039268,0.550205577,DB0107610067973_,0.597463294,-0.229807788,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,atorvastatin,DB01076
,1257280,DB09035,10048294,33,4693,51,6639,0.739526457,0.915357911,0.57128719,1.448632723,0.85016024,DB0903510048294_,0.16233043,-0.088440131,NA,10048294,Mental status changes,10037175,Psychiatric disorders,Psych,nivolumab,DB09035
,1258823,DB05829,10033775,128,1478,8,201,0.034996525,2.17517547,1.04947277,5.224770779,0.095408771,DB0582910033775_,2.349584761,0.777109337,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,parathyroid hormone,DB05829
,1260895,DB00373,10064355,36,1796,22,1265,0.686861861,1.152478363,0.65627864,2.06717042,0.811149681,DB0037310064355_,0.209302679,0.141914722,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,timolol,DB00373
,1261455,DB00437,10067973,19,6902,36,11510,0.780486276,0.88012691,0.476485137,1.577056586,0.880475612,DB0043710067973_,0.12729305,-0.127689167,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,allopurinol,DB00437
,1264265,DB00987,10028533,26,2078,31,2897,0.590346627,1.169228623,0.664629386,2.041829259,0.736916992,DB0098710028533_,0.305280023,0.156344235,NA,10028533,Myelodysplastic syndrome,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cytarabine,DB00987
,1264477,DB09076,10012735,36,772,28,582,0.898062016,0.969289824,0.567803365,1.669782613,0.956338178,DB0907610012735_,0.044643686,-0.031191616,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,umeclidinium,DB09076
,1265489,DB08931,10074414,60,6517,17,2429,0.368369081,1.315412594,0.755623962,2.409765463,0.538055696,DB0893110074414_,0.6197932,0.274150376,NA,10074414,Catheter management,10042613,Surgical and medical procedures,Surg,riociguat,DB08931
,1266608,DB09037,10067482,33,2493,27,2808,0.242642741,1.376563325,0.800152939,2.387322052,0.400858831,DB0903710067482_,0.914145955,0.319590049,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,pembrolizumab,DB09037
,1266949,DB00864,10076308,67,6802,80,8312,0.933665094,1.023424614,0.72730227,1.436259976,0.97427051,DB0086410076308_,0.026066283,0.023154468,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tacrolimus,DB00864
,1267149,DB09029,10020772,58,11286,49,7221,0.164345382,0.757361788,0.508177812,1.132731164,0.303230266,DB0902910020772_,1.193262809,-0.277914216,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,secukinumab,DB09029
,1267547,DB05676,10049414,37,47092,25,25304,0.424091552,0.795269281,0.4659639,1.378519104,0.592875569,DB0567610049414_,0.522770735,-0.229074503,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,1271388,DB00087,10005750,45,1324,9,738,0.003524068,2.78588767,1.33516151,6.518970021,0.015404977,DB0008710005750_,4.173064654,1.024566555,female,10005750,Blood pressure increased,10022891,Investigations,Inv,alemtuzumab,DB00087
,1271567,DB09302,10048959,34,2164,17,1530,0.256217557,1.413920752,0.765022692,2.709173433,0.417046691,DB0930210048959_,0.874557096,0.346366521,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1271634,DB01060,10065154,44,8543,22,5059,0.609889388,1.184384484,0.693836341,2.077491139,0.75213743,DB0106010065154_,0.284836219,0.169223217,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,amoxicillin,DB01060
,1273491,DB09128,10047899,171,1193,46,524,0.004369601,1.632404602,1.151968795,2.350543873,0.018344509,DB0912810047899_,3.99842496,0.490054144,NA,10047899,Weight increased,10022891,Investigations,Inv,brexpiprazole,DB09128
,1274035,DB09035,10028653,17,4709,57,6633,0.001237085,0.420134778,0.228803137,0.73374604,0.006557574,DB0903510028653_,5.027134566,-0.867179719,NA,10028653,Myositis,10028395,Musculoskeletal and connective tissue disorders,Musc,nivolumab,DB09035
,1274150,DB00567,10065154,41,4478,17,2064,0.777944339,1.11160969,0.61602638,2.092120675,0.878947192,DB0056710065154_,0.129030461,0.105809136,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,cephalexin,DB00567
,1274706,DB09302,10022061,86,2112,29,1518,0.000336116,2.13105247,1.376416203,3.385799942,0.002217575,DB0930210022061_,6.11134112,0.756615975,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1274707,DB09302,10013709,81,2117,62,1485,0.604859564,0.91645152,0.645658559,1.306135352,0.748052492,DB0930210013709_,0.290282127,-0.08724611,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1274713,DB09302,10010264,41,2157,19,1528,0.146145451,1.528466904,0.863324711,2.799773796,0.278617093,DB0930210010264_,1.277916865,0.42426521,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1274715,DB09302,10022095,42,2156,21,1526,0.245264648,1.415456503,0.81576411,2.527020591,0.404060248,DB0930210022095_,0.906191283,0.347452096,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1275351,DB09303,10033645,27,26204,31,18928,0.08377955,0.629148457,0.361146673,1.089691264,0.18472825,DB0930310033645_,1.688869455,-0.46338803,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1275816,DB09035,10008190,26,4700,47,6643,0.341866964,0.781900054,0.464120611,1.290825768,0.5110776,DB0903510008190_,0.671233841,-0.246028355,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,nivolumab,DB09035
,1276865,DB09303,10003658,50,26181,39,18920,0.747627025,0.926491143,0.597094322,1.446998983,0.856567708,DB0930310003658_,0.154821912,-0.076350793,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,evolocumab,DB09303
,1277924,DB09303,10054112,137,26094,85,18874,0.276095411,1.165774352,0.88238098,1.547747558,0.439495405,DB0930310054112_,0.822128016,0.153385546,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,evolocumab,DB09303
,1278058,DB09331,10003549,45,2040,59,2370,0.55263313,0.886123955,0.584700142,1.335002128,0.706412578,DB0933110003549_,0.347555825,-0.120898435,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,daratumumab,DB09331
,1278067,DB09331,10016173,37,2048,31,2398,0.179243642,1.397408245,0.840242517,2.338324393,0.322932187,DB0933110016173_,1.130312927,0.334619268,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,daratumumab,DB09331
,1278350,DB09303,10022075,83,26148,42,18917,0.069080534,1.429679982,0.974479792,2.125603064,0.159692348,DB0930310022075_,1.834506139,0.35745063,NA,10022075,Injection site induration,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1278351,DB09303,10022112,67,26164,20,18939,0.000285762,2.424853706,1.452784556,4.221096713,0.001939137,DB0930310022112_,6.24551224,0.885771195,NA,10022112,Injection site warmth,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1278352,DB09303,10005557,433,25798,319,18640,0.794351518,0.980741744,0.845626573,1.138342861,0.888585154,DB0930310005557_,0.118124796,-0.019446112,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,evolocumab,DB09303
,1278364,DB09303,10023644,58,26173,39,18920,0.758240749,1.075069176,0.703903984,1.65785835,0.86499536,DB0930310023644_,0.145031137,0.072385009,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,evolocumab,DB09303
,1278395,DB09303,10015090,61,26170,47,18912,0.770015894,0.937927412,0.630349409,1.403331171,0.874025881,DB0930310015090_,0.134645292,-0.064082719,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1278396,DB09303,10042674,101,26130,48,18911,0.015857171,1.522827933,1.069148818,2.195620755,0.051489283,DB0930310042674_,2.966381595,0.420569088,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1278958,DB00563,10061309,30,46616,32,15316,5.37712415455041e-06,0.308029491,0.180744677,0.523626786,6.30268487858896e-05,DB0056310061309_,9.671949751,-1.177559749,male,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,methotrexate,DB00563
,1279738,DB09292,10047513,29,4500,52,8210,1,1.017485519,0.621857846,1.635396321,1,DB0929210047513_,0,0.017334406,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,sacubitril,DB09292
,1279779,DB00598,10010144,41,1547,13,1015,0.023593253,2.068739419,1.080146287,4.229675361,0.070275784,DB0059810010144_,2.655328001,0.726939445,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,labetalol,DB00598
,1279834,DB00531,10061494,34,7218,37,6479,0.474984681,0.824850874,0.501607885,1.352685077,0.640583497,DB0053110061494_,0.445375805,-0.192552668,NA,10061494,Rhinovirus infection,10021881,Infections and infestations,Infec,cyclophosphamide,DB00531
,1279928,DB09035,10060933,90,4636,108,6582,0.245048093,1.183109093,0.882008457,1.583932051,0.403804722,DB0903510060933_,0.90682388,0.168145798,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,nivolumab,DB09035
,1279938,DB09331,10053762,67,2018,74,2355,0.796969501,1.0566253,0.743509127,1.499311311,0.890074285,DB0933110053762_,0.116450354,0.05508015,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,daratumumab,DB09331
,1279966,DB09303,10011906,126,26105,173,18786,3.5394139728045e-08,0.524144454,0.412938352,0.663731514,7.03466890549462e-07,DB0930310011906_,14.16724503,-0.645987958,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1280604,DB06791,10011906,35,744,32,506,0.252333373,0.74405013,0.441024694,1.259109052,0.412460413,DB0679110011906_,0.885615046,-0.295646867,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,lanreotide,DB06791
,1288518,DB09073,10047899,215,20045,11,779,0.375009246,0.75959869,0.413812652,1.551088823,0.54481791,DB0907310047899_,0.607303651,-0.274965025,NA,10047899,Weight increased,10022891,Investigations,Inv,palbociclib,DB09073
,1288776,DB01190,10012434,59,4875,22,2263,0.403642137,1.244848204,0.749239997,2.139199037,0.573344154,DB0119010012434_,0.556269124,0.219013598,NA,10012434,Dermatitis allergic,10040785,Skin and subcutaneous tissue disorders,Skin,clindamycin,DB01190
,1289253,DB09122,10013709,50,1208,17,320,0.362710256,0.779249724,0.434709075,1.461763808,0.532250908,DB0912210013709_,0.630640268,-0.249423715,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,peginterferon beta-1a,DB09122
,1290575,DB00787,10076308,27,16973,37,17211,0.260791162,0.739971156,0.433065178,1.249258322,0.422281507,DB0078710076308_,0.862083109,-0.301144072,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,1292663,DB09292,10024570,50,4479,58,8204,0.019976123,1.579022668,1.057641863,2.349823364,0.061700632,DB0929210024570_,2.785461101,0.456806091,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,sacubitril,DB09292
,1292696,DB11581,10033661,50,1703,64,2696,0.284691148,1.236715306,0.832461278,1.828538386,0.4492193,DB1158110033661_,0.800244092,0.212458918,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,venetoclax,DB11581
,1294535,DB08895,10013990,57,28057,14,6632,0.880115862,0.962384764,0.529067217,1.871310617,0.949694712,DB0889510013990_,0.051614701,-0.038340946,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,tofacitinib,DB08895
,1294777,DB09292,10020772,46,4483,97,8165,0.43039956,0.863743267,0.593283479,1.241585083,0.598843525,DB0929210020772_,0.512754943,-0.146479699,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,sacubitril,DB09292
,1294844,DB00635,10057293,28,33025,35,23759,0.029936574,0.575558817,0.337151581,0.974091375,0.084574683,DB0063510057293_,2.47012031,-0.552413854,NA,10057293,West Nile viral infection,10021881,Infections and infestations,Infec,prednisone,DB00635
,1295598,DB00368,10001551,21,639,31,767,0.482818669,0.813230051,0.439479267,1.477574092,0.647065147,DB0036810001551_,0.435308299,-0.206741244,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,norepinephrine,DB00368
,1296996,DB09029,10017577,72,11272,36,7234,0.2363604,1.283506514,0.847856535,1.974099323,0.393584613,DB0902910017577_,0.932459207,0.249595796,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,1297004,DB09292,10022437,74,4455,96,8166,0.02910571,1.412837416,1.026594424,1.937983502,0.082724574,DB0929210022437_,2.49223858,0.345600034,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,sacubitril,DB09292
,1298394,DB09302,10022094,50,2148,13,1534,0.000681141,2.746042625,1.463350434,5.530266011,0.004001744,DB0930210022094_,5.521025085,1.01016083,female,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1298395,DB09302,10037087,93,2105,40,1507,0.007113358,1.664281406,1.129797994,2.490332103,0.02713513,DB0930210037087_,3.606926094,0.509393442,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,alirocumab,DB09302
,1299532,DB00287,10022806,40,1361,18,799,0.408907887,1.304445556,0.725051713,2.434644379,0.578276912,DB0028710022806_,0.547702439,0.265778089,NA,10022806,Intraocular pressure increased,10022891,Investigations,Inv,travoprost,DB00287
,1299541,DB09343,10012735,168,1351,201,1682,0.739463881,1.040609279,0.832092185,1.300107246,0.85016024,DB0934310012735_,0.16233043,0.039806386,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,tipiracil,DB09343
,1299795,DB09302,10022093,57,2141,20,1527,0.00677163,2.032304825,1.196610716,3.587146357,0.026102406,DB0930210022093_,3.645727802,0.709170531,NA,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1300787,DB09045,10000381,49,2300,45,1679,0.291488675,0.794940493,0.516725661,1.22545839,0.456948793,DB0904510000381_,0.783183944,-0.229488019,NA,10000381,Accidental overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,dulaglutide,DB09045
,1301144,DB01281,10040808,58,8874,21,1777,0.023329925,0.553102912,0.329674494,0.962042665,0.069637416,DB0128110040808_,2.664453264,-0.592211198,NA,10040808,Skin cancer,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,abatacept,DB01281
,1301454,DB09292,10019303,37,4492,50,8212,0.177253364,1.352744949,0.858386421,2.114816926,0.32034548,DB0929210019303_,1.13835524,0.302135824,NA,10019303,Heart rate increased,10022891,Investigations,Inv,sacubitril,DB09292
,1301508,DB09303,10005191,37,26194,25,18934,0.897682312,1.069810781,0.626746972,1.854683922,0.956338178,DB0930310005191_,0.044643686,0.067481793,NA,10005191,Blister,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1301540,DB09303,10067484,63,26168,56,18903,0.265465838,0.812676182,0.557643776,1.186955373,0.427480827,DB0930310067484_,0.84984584,-0.207422549,NA,10067484,Adverse reaction,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1301555,DB09303,10064355,120,26111,82,18877,0.721289357,1.057986728,0.791796556,1.419553138,0.835643985,DB0930310064355_,0.179552611,0.056367788,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,1301557,DB09303,10036790,81,26150,76,18883,0.10547659,0.76962244,0.555471218,1.067325676,0.219330893,DB0930310036790_,1.51717376,-0.261855222,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1301561,DB09303,10016173,212,26019,90,18869,1.38265268935402e-05,1.708225833,1.327782918,2.212539001,0.000144362,DB0930310016173_,8.843189484,0.535455307,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,1301562,DB09303,10050584,242,25989,108,18851,2.07455902984762e-05,1.625290125,1.289177327,2.060193637,0.00020624,DB0930310050584_,8.486471337,0.485686339,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,1301563,DB09303,10023230,37,26194,38,18921,0.129436293,0.703349121,0.434795173,1.13677813,0.254829822,DB0930310023230_,1.367159321,-0.351901894,NA,10023230,Joint stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1301585,DB09303,10005555,56,26175,26,18933,0.072522294,1.557910845,0.961726131,2.58579839,0.165695902,DB0930310005555_,1.797601087,0.443345722,NA,10005555,Blood glucose decreased,10022891,Investigations,Inv,evolocumab,DB09303
,1301661,DB09303,10003553,64,26167,22,18937,0.002041064,2.10525467,1.278730409,3.591235438,0.00988655,DB0930310003553_,4.616580066,0.744436443,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1302345,DB00381,10074300,37,29323,21,22866,0.289685478,1.373918951,0.783217648,2.471104277,0.454847991,DB0038110074300_,0.787792002,0.317667204,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,amlodipine,DB00381
,1302710,DB09029,10027175,51,11293,30,7240,0.733722374,1.08988829,0.680342478,1.774162683,0.845612865,DB0902910027175_,0.16769363,0.086075205,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,secukinumab,DB09029
,1302716,DB09302,10013573,52,2146,35,1512,0.912400766,1.046778277,0.665324448,1.664578669,0.960643066,DB0930210013573_,0.040152359,0.04571714,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,alirocumab,DB09302
,1303060,DB01212,10067482,56,1963,41,1900,0.182996488,1.321921887,0.863262224,2.039273572,0.32766807,DB0121210067482_,1.115754166,0.279086653,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,ceftriaxone,DB01212
,1303267,DB09107,10016334,48,1167,32,971,0.361736374,1.247947532,0.774594051,2.034410321,0.531498397,DB0910710016334_,0.632055097,0.221500228,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,methoxy polyethylene glycol-epoetin beta,DB09107
,1311451,DB06262,10028372,34,3766,45,4269,0.571374787,0.856486912,0.530821188,1.37047807,0.72156175,DB0626210028372_,0.326337319,-0.154916243,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,droxidopa,DB06262
,1311994,DB09071,10016322,20,964,30,752,0.029497675,0.520257938,0.277635959,0.955462533,0.083604313,DB0907110016322_,2.481660172,-0.653430557,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,tasimelteon,DB09071
,1312761,DB09128,10053762,205,1159,92,478,0.534262594,0.919032571,0.698287604,1.215946489,0.690876062,DB0912810053762_,0.369794831,-0.084433716,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,brexpiprazole,DB09128
,1313389,DB09029,10047899,92,11252,40,7230,0.039566354,1.477840341,1.007797927,2.201868673,0.104791337,DB0902910047899_,2.255784176,0.390581793,NA,10047899,Weight increased,10022891,Investigations,Inv,secukinumab,DB09029
,1313871,DB09076,10019211,54,754,17,593,0.000808094,2.49667265,1.407636876,4.644018195,0.004614983,DB0907610019211_,5.378447164,0.914958905,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,umeclidinium,DB09076
,1314085,DB00864,10015108,71,6798,55,8337,0.011622133,1.583088344,1.095916398,2.297361961,0.040142937,DB0086410015108_,3.215308759,0.459377587,NA,10015108,Epstein-Barr virus infection,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,1315415,DB00904,10010356,42,23027,54,14402,0.000478788,0.486454135,0.316933784,0.742195183,0.002980448,DB0090410010356_,5.815681684,-0.720612657,NA,10010356,Congenital anomaly,10010331,"Congenital, familial and genetic disorders",Cong,ondansetron,DB00904
,1317233,DB09292,10042682,45,4484,40,8222,0.00091592,2.062755786,1.314928765,3.245802875,0.005125601,DB0929210042682_,5.27350758,0.724042849,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,1318149,DB00190,10000125,21,3276,43,4631,0.202214698,0.690401183,0.388402733,1.19180485,0.351639929,DB0019010000125_,1.045147557,-0.370482426,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,carbidopa,DB00190
,1318289,DB00688,10029444,21,6469,68,5310,2.63110813015232e-09,0.253521227,0.147373428,0.419398995,6.73077150375218e-08,DB0068810029444_,16.51399097,-1.372307726,male,10029444,Nocardiosis,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,1318388,DB08932,10005758,36,19407,17,6580,0.269035913,0.71800446,0.392683441,1.364136702,0.431564078,DB0893210005758_,0.84033928,-0.331279498,NA,10005758,Blood pressure systolic decreased,10022891,Investigations,Inv,macitentan,DB08932
,1318545,DB00254,10064848,51,5884,32,3356,0.731114574,0.909023053,0.571788222,1.464783211,0.843600616,DB0025410064848_,0.1700761,-0.095384825,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,doxycycline,DB00254
,1319369,DB08932,10048762,41,19402,9,6588,0.25888463,1.546778921,0.74003073,3.621622696,0.41997053,DB0893210048762_,0.867570736,0.436174653,NA,10048762,Tooth infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,1319852,DB09302,10046735,40,2158,21,1526,0.296267225,1.346821291,0.771847709,2.414594043,0.462122283,DB0930210046735_,0.771925741,0.297747216,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,alirocumab,DB09302
,1320375,DB09292,10013709,138,4391,240,8022,0.662439565,1.050470897,0.842952981,1.304959982,0.794226468,DB0929210013709_,0.230386634,0.049238537,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,1321453,DB09331,10040047,24,2061,65,2364,0.000226308,0.423605421,0.25260529,0.688873352,0.001598846,DB0933110040047_,6.438473264,-0.858952869,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,daratumumab,DB09331
,1322278,DB09303,10013990,32,26199,18,18941,0.473915503,1.285266096,0.699757628,2.432678175,0.63973683,DB0930310013990_,0.44669839,0.250965775,NA,10013990,Dysuria,10038359,Renal and urinary disorders,Renal,evolocumab,DB09303
,1322309,DB09303,10019974,59,26172,42,18917,1,1.015355776,0.67176159,1.546759747,1,DB0930310019974_,0,0.015239069,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,evolocumab,DB09303
,1322319,DB09303,10047340,57,26174,39,18920,0.836416854,1.056487691,0.690559561,1.631473508,0.915542875,DB0930310047340_,0.088238083,0.054949907,NA,10047340,Vertigo,10013993,Ear and labyrinth disorders,Ear,evolocumab,DB09303
,1322362,DB09303,10002953,46,26185,17,18942,0.015333404,1.957372866,1.10057886,3.643085323,0.050178119,DB0930310002953_,2.992176217,0.671603199,NA,10002953,Aphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1322726,DB06273,10029354,47,5048,21,1389,0.074886343,0.615883365,0.359568182,1.088546023,0.169659327,DB0627310029354_,1.773962809,-0.484697676,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,tocilizumab,DB06273
,1322996,DB00028,10023232,61,13397,21,5594,0.543755677,1.212876123,0.727320087,2.099374872,0.698922612,DB0002810023232_,0.358215255,0.1929945,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,human immunoglobulin g,DB00028
,1323689,DB01073,10047216,21,1044,40,1610,0.507879298,0.809698628,0.450826097,1.415487116,0.668566789,DB0107310047216_,0.402618979,-0.211093164,NA,10047216,Venoocclusive liver disease,10019805,Hepatobiliary disorders,Hepat,fludarabine,DB01073
,1323849,DB11581,10040047,68,1685,114,2646,0.69856873,0.936690678,0.678886356,1.284380305,0.818776379,DB1158110040047_,0.199944274,-0.065402171,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,venetoclax,DB11581
,1323917,DB08932,10067973,131,19312,42,6555,0.792973301,1.05866991,0.741733679,1.538477597,0.887780187,DB0893210067973_,0.119031104,0.057013318,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,1324513,DB09029,10040831,53,11291,25,7245,0.244715939,1.360300474,0.829699737,2.286546144,0.403485037,DB0902910040831_,0.907615876,0.307705612,NA,10040831,Skin disorder,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,1324719,DB05829,10020947,218,1388,31,178,0.594267691,0.901865009,0.595045485,1.403459641,0.740174034,DB0582910020947_,0.30086994,-0.103290427,NA,10020947,Hypocalcaemia,10027433,Metabolism and nutrition disorders,Metab,parathyroid hormone,DB05829
,1324756,DB09128,10037844,40,1324,13,557,0.54115879,1.294245239,0.67180622,2.65880433,0.696538393,DB0912810037844_,0.361632365,0.257927698,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,brexpiprazole,DB09128
,1324907,DB09107,10037844,87,1128,61,942,0.34717605,1.190959372,0.838406063,1.700378209,0.51659473,DB0910710037844_,0.6604966,0.174759178,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,methoxy polyethylene glycol-epoetin beta,DB09107
,1330727,DB00099,10076573,34,2351,17,1938,0.11859392,1.648473727,0.892545142,3.15674778,0.239098077,DB0009910076573_,1.430881448,0.499849846,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,filgrastim,DB00099
,1346244,DB08868,10027145,190,9012,41,2470,0.194745575,1.270092239,0.899306073,1.831883014,0.342687026,DB0886810027145_,1.07093771,0.239089527,NA,10027145,Melanocytic naevus,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fingolimod,DB08868
,1346246,DB08868,10064127,45,9157,8,2503,0.315489212,1.537483617,0.716077888,3.781199579,0.483127032,DB0886810064127_,0.727475653,0.430147065,NA,10064127,Solar lentigo,10040785,Skin and subcutaneous tissue disorders,Skin,fingolimod,DB08868
,1348998,DB00924,10037162,79,10083,13,4238,0.000789041,2.554045091,1.409037204,5.012687037,0.004522448,DB0092410037162_,5.398701842,0.937678413,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,cyclobenzaprine,DB00924
,1349592,DB00169,10061296,43,38648,13,18162,0.196673525,1.554385119,0.820180689,3.151544503,0.344959535,DB0016910061296_,1.064328157,0.441080046,NA,10061296,Motor dysfunction,10029205,Nervous system disorders,Nerv,cholecalciferol,DB00169
,1356463,DB00005,10071148,40,128042,19,42400,0.226924191,0.69714153,0.39438341,1.274564756,0.382095536,DB0000510071148_,0.962084607,-0.360766833,NA,10071148,Product distribution issue,10077536,Product issues,Prod,etanercept,DB00005
,1361329,DB09292,10064355,22,4507,41,8221,1,0.978760362,0.554539241,1.684301289,1,DB0929210064355_,0,-0.021468445,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,sacubitril,DB09292
,1361339,DB09303,10024570,53,26178,39,18920,1,0.982186328,0.637086316,1.526069205,1,DB0930310024570_,0,-0.017974246,NA,10024570,Lip swelling,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1366067,DB09292,10063829,13,4516,39,8223,0.145535471,0.606975018,0.296963119,1.163043004,0.277786642,DB0929210063829_,1.280901936,-0.499267645,NA,10063829,Device malfunction,10077536,Product issues,Prod,sacubitril,DB09292
,1366438,DB05676,10074902,45,47084,11,25318,0.016613368,2.199740029,1.119916657,4.717376096,0.053390681,DB0567610074902_,2.930119062,0.788339185,NA,10074902,Expired product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,apremilast,DB05676
,1369119,DB09128,10022437,46,1318,15,555,0.476010313,1.291151304,0.700875755,2.511429131,0.641440125,DB0912810022437_,0.444039436,0.255534304,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,brexpiprazole,DB09128
,1371643,DB09303,10041232,99,26132,53,18906,0.083718509,1.351397674,0.958016254,1.92491086,0.184632378,DB0930310041232_,1.689388574,0.301139371,NA,10041232,Sneezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1371654,DB09303,10041466,37,26194,20,18939,0.347584331,1.337592745,0.756221243,2.43309523,0.517107434,DB0930310041466_,0.659504624,0.290871539,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1371665,DB09303,10056871,74,26157,67,18892,0.199762532,0.79772363,0.565056367,1.127886401,0.348784599,DB0930310056871_,1.053300743,-0.22599307,NA,10056871,Device failure,10077536,Product issues,Prod,evolocumab,DB09303
,1371700,DB09303,10073753,130,26101,43,18916,3.01788882455645e-06,2.19096966,1.540256536,3.17128695,3.80913362561662e-05,DB0930310073753_,10.1755237,0.784344213,NA,10073753,Fear of injection,10037175,Psychiatric disorders,Psych,evolocumab,DB09303
,1371703,DB09303,10033775,179,26052,98,18861,0.02780368,1.322353796,1.027206478,1.710682795,0.079792523,DB0930310033775_,2.528325478,0.279413327,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1371712,DB09303,10040742,43,26188,40,18919,0.266360112,0.776624196,0.492857683,1.226271724,0.42850086,DB0930310040742_,0.847462534,-0.252798705,NA,10040742,Sinus congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1371713,DB09303,10070488,60,26171,42,18917,0.920188413,1.0326067,0.684281782,1.570957617,0.964688501,DB0930310070488_,0.035950027,0.032086382,NA,10070488,Upper-airway cough syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1371725,DB09303,10047924,39,26192,23,18936,0.520012348,1.225897785,0.71389659,2.150674263,0.679146897,DB0930310047924_,0.386917832,0.203673461,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1371739,DB09303,10036018,41,26190,39,18920,0.256683367,0.759473118,0.477625135,1.209419561,0.417531889,DB0930310036018_,0.873394356,-0.275130352,NA,10036018,Pollakiuria,10038359,Renal and urinary disorders,Renal,evolocumab,DB09303
,1371742,DB09303,10048865,86,26145,85,18874,0.043408504,0.730405388,0.534540253,0.998212022,0.112446294,DB0930310048865_,2.185279562,-0.314155573,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,evolocumab,DB09303
,1374053,DB09045,10018484,38,2311,34,1690,0.402093997,0.817364491,0.498639902,1.344640109,0.571902314,DB0904510018484_,0.558787083,-0.201670151,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,dulaglutide,DB09045
,1374583,DB08895,10023003,49,28065,7,6639,0.23726671,1.655870857,0.745639153,4.335694739,0.394611792,DB0889510023003_,0.929852802,0.504327068,NA,10023003,Irritable bowel syndrome,10017947,Gastrointestinal disorders,Gastr,tofacitinib,DB08895
,1375957,DB09343,10025482,35,1484,44,1839,1,0.985745087,0.610369492,1.58134383,1,DB0934310025482_,0,-0.01435749,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,tipiracil,DB09343
,1383047,DB00203,10077107,93,13785,26,8912,6.73039429047623e-05,2.312395136,1.482066881,3.725722275,0.000567847,DB0020310077107_,7.473658932,0.838283843,NA,10077107,Complication associated with device,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,1383048,DB01240,10077107,151,5600,32,1544,0.202095692,1.300975264,0.87953397,1.978025339,0.351479489,DB0124010077107_,1.045603922,0.263114186,NA,10077107,Complication associated with device,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,1383604,DB08932,10013969,92,19351,21,6576,0.104438164,1.488706697,0.918169295,2.520788284,0.217653687,DB0893210013969_,1.52485007,0.397907755,NA,10013969,Dyspnoea at rest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,1383640,DB00005,10077692,362,127720,66,42353,2.324711615396e-06,1.818725529,1.395482975,2.402428056,3.01976994369577e-05,DB0000510077692_,10.40774481,0.598135997,NA,10077692,Liver function test increased,10022891,Investigations,Inv,etanercept,DB00005
,1383641,DB00563,10077692,1070,45576,218,15130,9.77842828729641e-12,1.629324979,1.40556176,1.895799937,3.74128075009587e-10,DB0056310077692_,21.70642293,0.488165806,NA,10077692,Liver function test increased,10022891,Investigations,Inv,methotrexate,DB00563
,1385587,DB08931,10047924,64,6513,18,2428,0.320262958,1.325421646,0.773920732,2.381484412,0.488485591,DB0893110047924_,0.716445304,0.281730632,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,1386087,DB00316,10016062,32,65442,22,36931,0.480996369,0.820858545,0.462300687,1.482959261,0.64564165,DB0031610016062_,0.43751065,-0.19740448,NA,10016062,Facial paralysis,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,1389246,DB00264,10077361,46,29561,46,24846,0.404639155,0.840504087,0.546018799,1.293808536,0.57438787,DB0026410077361_,0.554450379,-0.173753464,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,1389247,DB00437,10077361,27,6894,31,11515,0.174161757,1.454691298,0.834617671,2.521319687,0.316356849,DB0043710077361_,1.150884432,0.374793712,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,allopurinol,DB00437
,1389248,DB00480,10077361,39,67389,46,67616,0.515346894,0.850683887,0.54060158,1.332567103,0.675163786,DB0048010077361_,0.392799971,-0.16171468,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,1389250,DB01234,10077361,73,31552,115,32773,0.005416458,0.659354661,0.484645141,0.892147998,0.021799357,DB0123410077361_,3.825874808,-0.416493709,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,1390488,DB00761,10077361,28,15279,32,8593,0.006756073,0.492109294,0.285284823,0.844386777,0.026053996,DB0076110077361_,3.647584137,-0.709054444,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,1390490,DB00904,10077361,40,23029,50,14406,0.001085471,0.500446671,0.321571183,0.774373383,0.005894349,DB0090410077361_,5.133761143,-0.692254238,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,1391610,DB05676,10073317,49,47080,9,25320,0.001368068,2.928023966,1.423010829,6.78115421,0.007131319,DB0567610073317_,4.943259116,1.074327781,female,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,apremilast,DB05676
,1391743,DB00316,10077692,149,65325,90,36863,0.637014322,0.934234036,0.714139513,1.22796961,0.774381848,DB0031610077692_,0.255690184,-0.068028298,NA,10077692,Liver function test increased,10022891,Investigations,Inv,acetaminophen,DB00316
,1391748,DB01050,10077692,47,18061,15,9356,0.108343594,1.623109857,0.891170247,3.12697479,0.223550621,DB0105010077692_,1.498117398,0.484343974,NA,10077692,Liver function test increased,10022891,Investigations,Inv,ibuprofen,DB01050
,1391749,DB01234,10077692,40,31585,65,32823,0.031133524,0.63951256,0.420028205,0.962988101,0.087201735,DB0123410077692_,2.439531054,-0.447049018,NA,10077692,Liver function test increased,10022891,Investigations,Inv,dexamethasone,DB01234
,1392650,DB09292,10028810,68,4461,87,8175,0.028158072,1.432233344,1.025050545,1.994370783,0.080593991,DB0929210028810_,2.518331184,0.359235005,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,sacubitril,DB09292
,1392675,DB09331,10035226,109,1976,125,2304,0.94633615,1.016744407,0.773458936,1.334946085,0.984834038,DB0933110035226_,0.015282142,0.016605765,NA,10035226,Plasma cell myeloma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,daratumumab,DB09331
,1392687,DB00338,10077512,168,33506,164,22108,0.000388897,0.67593769,0.541426304,0.84394748,0.002505738,DB0033810077512_,5.989171884,-0.391654381,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,omeprazole,DB00338
,1392691,DB01136,10077512,31,9853,46,11069,0.253531808,0.757094815,0.463690322,1.221010046,0.414044972,DB0113610077512_,0.881780682,-0.278266782,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,carvedilol,DB01136
,1393117,DB06605,10019063,31,14042,42,12991,0.126852007,0.682865393,0.414731031,1.113152727,0.251251543,DB0660510019063_,1.381300677,-0.381457521,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,apixaban,DB06605
,1393163,DB06605,10065154,52,14021,71,12962,0.037156707,0.677091474,0.463736686,0.982892247,0.099883825,DB0660510065154_,2.30374752,-0.389948898,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,apixaban,DB06605
,1393841,DB00820,10077107,86,11829,18,5798,0.000497364,2.341739101,1.39576114,4.141527427,0.003078222,DB0082010077107_,5.783403118,0.850893859,NA,10077107,Complication associated with device,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,1393842,DB06403,10077107,73,21398,15,6646,0.166905767,1.511486854,0.858470335,2.839452998,0.306705683,DB0640310077107_,1.18186668,0.413093838,NA,10077107,Complication associated with device,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,1394767,DB09292,10013578,16,4513,49,8213,0.069806118,0.594260312,0.315055352,1.064505047,0.160959148,DB0929210013578_,1.826604686,-0.520437819,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,1395962,DB11595,10040047,32,1081,32,1002,0.800321189,0.926970095,0.545405458,1.575501205,0.892049316,DB1159510040047_,0.114233861,-0.075833974,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,atezolizumab,DB11595
,1396316,DB09303,10001949,96,26135,66,18893,0.811026738,1.051497807,0.760167738,1.461967929,0.898349676,DB0930310001949_,0.107195892,0.05021563,NA,10001949,Amnesia,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1396324,DB06605,10040984,30,14043,22,13011,0.487713835,1.263411779,0.704392937,2.299897199,0.651449966,DB0660510040984_,0.428554683,0.233815823,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,apixaban,DB06605
,1396345,DB08904,10029148,47,11563,15,3544,0.880977571,0.960350078,0.526877262,1.851443798,0.950146501,DB0890410029148_,0.051139095,-0.040457397,NA,10029148,Nephrolithiasis,10038359,Renal and urinary disorders,Renal,certolizumab pegol,DB08904
,1396889,DB00213,10077361,33,18862,52,13369,0.000358523,0.449809458,0.281501578,0.709563754,0.002340146,DB0021310077361_,6.057541858,-0.798931214,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,1396892,DB00695,10077361,57,27992,57,20471,0.106356848,0.731330543,0.497370526,1.075331764,0.220698647,DB0069510077361_,1.510957097,-0.312889742,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,1397140,DB00374,10077107,106,17610,31,5693,0.690337016,1.10541122,0.733831107,1.709108488,0.813196557,DB0037410077107_,0.206782431,0.100217411,NA,10077107,Complication associated with device,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,1397415,DB09128,10076573,34,1330,18,552,0.441111335,0.784038082,0.426323115,1.48801822,0.609280685,DB0912810076573_,0.495476222,-0.243297686,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,brexpiprazole,DB09128
,1398109,DB08931,10035528,38,6539,12,2434,0.749998039,1.178696234,0.601721313,2.481846358,0.858423621,DB0893110035528_,0.152657571,0.164408941,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,riociguat,DB08931
,1398715,DB09303,10005425,232,25999,140,18819,0.091611337,1.199485708,0.967501819,1.491459253,0.19784767,DB0930310005425_,1.620257889,0.181892888,NA,10005425,Blood cholesterol increased,10022891,Investigations,Inv,evolocumab,DB09303
,1398719,DB09303,10005839,144,26087,122,18837,0.212627057,0.85230174,0.664466544,1.094654545,0.364575754,DB0930310005839_,1.009020918,-0.15981466,NA,10005839,Blood triglycerides increased,10022891,Investigations,Inv,evolocumab,DB09303
,1398729,DB09303,10020060,22,26209,35,18924,0.004358324,0.453858722,0.253539601,0.795957195,0.018307399,DB0930310020060_,4.000449965,-0.789969314,NA,10020060,High density lipoprotein decreased,10022891,Investigations,Inv,evolocumab,DB09303
,1398754,DB09303,10012378,99,26132,69,18890,0.875602183,1.037162445,0.754588697,1.432432085,0.946543425,DB0930310012378_,0.05493843,0.036488566,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,evolocumab,DB09303
,1399074,DB00331,10077361,28,24918,48,20704,0.002492934,0.484686371,0.292711467,0.788663368,0.011631626,DB0033110077361_,4.454027517,-0.724253254,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,1399075,DB00512,10077361,73,4664,92,5006,0.34583493,0.851676662,0.615967339,1.173939274,0.515296661,DB0051210077361_,0.663012504,-0.160548329,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,vancomycin,DB00512
,1399076,DB00787,10077361,33,16967,58,17190,0.011542513,0.576455968,0.363925694,0.899306153,0.039938781,DB0078710077361_,3.220407481,-0.550856321,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,1399193,DB09303,10057668,39,26192,31,18928,0.717085498,0.909160009,0.552563357,1.507612794,0.832737296,DB0930310057668_,0.183037058,-0.095234173,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1399203,DB09303,10022111,50,26181,45,18914,0.298938017,0.802712316,0.525545437,1.229194988,0.46490464,DB0930310022111_,0.76592297,-0.219758891,NA,10022111,Injection site vesicles,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1399374,DB09570,10053762,233,3668,255,3680,0.374456469,0.91673815,0.759625576,1.105931153,0.544342783,DB0957010053762_,0.608176115,-0.086933399,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ixazomib,DB09570
,1399375,DB09570,10067482,75,3826,93,3842,0.185435684,0.809847445,0.587305874,1.113613042,0.330721737,DB0957010067482_,1.10647793,-0.210909389,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,1399660,DB00544,10048610,31,2404,30,2623,0.699525606,1.127440638,0.657972529,1.934383836,0.819404646,DB0054410048610_,0.199177244,0.119950142,NA,10048610,Cardiotoxicity,10007541,Cardiac disorders,Card,fluorouracil,DB00544
,1399756,DB09107,10033371,47,1168,31,972,0.35515139,1.26157819,0.777998068,2.071542938,0.524948226,DB0910710033371_,0.644455639,0.232363469,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,methoxy polyethylene glycol-epoetin beta,DB09107
,1401039,DB00338,10077692,74,33600,51,22221,0.854995907,0.959561622,0.662420601,1.399661147,0.929677846,DB0033810077692_,0.072917155,-0.041278742,NA,10077692,Liver function test increased,10022891,Investigations,Inv,omeprazole,DB00338
,1401041,DB00904,10077692,64,23005,39,14417,0.919613633,1.028414947,0.679691952,1.57397975,0.964404362,DB0090410077692_,0.03624461,0.02801873,NA,10077692,Liver function test increased,10022891,Investigations,Inv,ondansetron,DB00904
,1401042,DB01015,10077692,40,9847,21,9360,0.028822919,1.810495818,1.041504225,3.234751316,0.082094644,DB0101510077692_,2.499882504,0.59360074,NA,10077692,Liver function test increased,10022891,Investigations,Inv,sulfamethoxazole,DB01015
,1401591,DB09343,10061428,92,1427,134,1749,0.239141039,0.841532687,0.632213037,1.116286704,0.396870895,DB0934310061428_,0.924144252,-0.172530423,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,tipiracil,DB09343
,1401879,DB00019,10076573,3988,15024,1944,7585,0.265450141,1.035690421,0.974171866,1.101257365,0.42747802,DB0001910076573_,0.849852407,0.035068278,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,1401895,DB00019,10003051,509,18503,220,9309,0.067187064,1.163986852,0.989787789,1.372448367,0.156325747,DB0001910003051_,1.855813326,0.151851054,NA,10003051,Application site pain,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,1401896,DB00019,10063072,175,18837,76,9453,0.313646682,1.155515645,0.876805958,1.535071533,0.481132363,DB0001910063072_,0.731612865,0.144546691,NA,10063072,Application site discomfort,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,1402003,DB00019,10050114,136,18876,37,9492,0.00064336,1.848317125,1.275733238,2.737981093,0.003819475,DB0001910050114_,5.567642218,0.614275563,NA,10050114,Application site bruise,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,1402060,DB00019,10068945,109,18903,50,9479,0.673400795,1.093165279,0.774527688,1.561601475,0.801900054,DB0001910068945_,0.2207713,0.089077413,NA,10068945,Incorrect dose administered by device,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,1402064,DB00019,10003041,87,18925,22,9507,0.0030154,1.986528811,1.232045935,3.333703945,0.013567737,DB0001910003041_,4.300060582,0.6863888,NA,10003041,Application site erythema,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,1402114,DB00019,10022067,47,18965,22,9507,0.89843086,1.070937866,0.632276428,1.867350019,0.956410053,DB0001910022067_,0.044568532,0.068534775,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,pegfilgrastim,DB00019
,1402262,DB06186,10076308,131,2078,197,3449,0.411894125,1.103683323,0.872011997,1.393373289,0.581328475,DB0618610076308_,0.54243932,0.098653061,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ipilimumab,DB06186
,1402516,DB06643,10056723,90,52331,13,7502,1,0.992469325,0.55170275,1.936762891,1,DB0664310056723_,0,-0.007559173,NA,10056723,Dental care,10042613,Surgical and medical procedures,Surg,denosumab,DB06643
,1402654,DB00316,10077605,49,65425,22,36931,0.390308971,1.257279755,0.745809188,2.183881926,0.560141482,DB0031610077605_,0.579565881,0.228950463,NA,10077605,Anal incontinence,10017947,Gastrointestinal disorders,Gastr,acetaminophen,DB00316
,1402662,DB00996,10077605,33,38920,18,22407,1,1.055488983,0.577157793,1.991408055,1,DB0099610077605_,0,0.054004151,NA,10077605,Anal incontinence,10017947,Gastrointestinal disorders,Gastr,gabapentin,DB00996
,1402845,DB09302,10028372,22,2176,34,1513,0.003793065,0.450001549,0.249665189,0.795616391,0.016343041,DB0930210028372_,4.113953097,-0.798504255,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,alirocumab,DB09302
,1402852,DB01076,10077692,74,25673,71,25512,0.868071105,1.035725673,0.737317762,1.455767813,0.941033901,DB0107610077692_,0.060776113,0.035102314,NA,10077692,Liver function test increased,10022891,Investigations,Inv,atorvastatin,DB01076
,1402902,DB09302,10076309,36,2162,36,1511,0.14702046,0.698971649,0.42579974,1.14738775,0.279808326,DB0930210076309_,1.27365046,-0.358145097,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,alirocumab,DB09302
,1403179,DB06262,10053762,55,3745,22,4292,1.53915398577617e-05,2.864800676,1.714770069,4.943560341,0.000158436,DB0626210053762_,8.750159092,1.052498776,female,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,droxidopa,DB06262
,1403252,DB00531,10076573,97,7155,13,6503,1.87053543891622e-15,6.780838265,3.7807196,13.20271062,1.21700554484933e-13,DB0053110076573_,29.73721284,1.914100732,female,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclophosphamide,DB00531
,1403903,DB09331,10011224,59,2026,55,2374,0.253635045,1.256916889,0.851232994,1.858503575,0.414138226,DB0933110011224_,0.881555482,0.228661809,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,daratumumab,DB09331
,1403904,DB09331,10020772,30,2055,29,2400,0.512112667,1.208100764,0.698055177,2.093800013,0.672354909,DB0933110020772_,0.39696894,0.18904951,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,daratumumab,DB09331
,1404313,DB09331,10011906,65,2020,89,2340,0.324753758,0.846065727,0.601346623,1.185121873,0.493205186,DB0933110011906_,0.706829993,-0.167158231,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,daratumumab,DB09331
,1404607,DB09570,10003988,83,3818,70,3865,0.28865199,1.200280798,0.859818173,1.679621184,0.453689354,DB0957010003988_,0.790342557,0.182555528,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ixazomib,DB09570
,1405470,DB00005,10077753,75,128007,24,42395,1,1.034995466,0.645981676,1.714559193,1,DB0000510077753_,0,0.034397046,NA,10077753,Frustration tolerance decreased,10037175,Psychiatric disorders,Psych,etanercept,DB00005
,1406291,DB09570,10003549,122,3779,110,3825,0.387332096,1.122574193,0.856881331,1.472117346,0.557406195,DB0957010003549_,0.584461051,0.115624435,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,1406568,DB00996,10077692,53,38900,25,22400,0.48051403,1.220722616,0.745119337,2.050643869,0.645309044,DB0099610077692_,0.438025938,0.199442992,NA,10077692,Liver function test increased,10022891,Investigations,Inv,gabapentin,DB00996
,1406569,DB08868,10077692,41,9161,27,2484,0.000559276,0.411783326,0.24676092,0.697622114,0.003386058,DB0886810077692_,5.68808888,-0.887257975,NA,10077692,Liver function test increased,10022891,Investigations,Inv,fingolimod,DB08868
,1407442,DB09570,10028813,299,3602,175,3760,2.00841698446709e-09,1.783370834,1.466398118,2.174005463,5.24763821438544e-08,DB0957010028813_,16.76290263,0.578505301,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ixazomib,DB09570
,1407765,DB09570,10023547,46,3855,70,3865,0.03119201,0.658885832,0.442817651,0.972265973,0.087330228,DB0957010023547_,2.438058617,-0.417205004,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,ixazomib,DB09570
,1407786,DB09570,10011906,385,3516,465,3470,0.005755079,0.817147904,0.706249617,0.945045765,0.022904423,DB0957010011906_,3.776425246,-0.201935167,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,1408028,DB09303,10044390,38,26193,14,18945,0.0340388,1.963162656,1.039419012,3.924060942,0.093471568,DB0930310044390_,2.370097976,0.674556773,NA,10044390,Transient ischaemic attack,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1409374,DB00619,10069326,64,2835,46,2448,0.384895906,1.201338791,0.806360823,1.802104887,0.555009403,DB0061910069326_,0.588770224,0.183436594,NA,10069326,Product substitution issue,10077536,Product issues,Prod,imatinib,DB00619
,1409627,DB09570,10019211,75,3826,32,3903,2.28832073191906e-05,2.390754642,1.556639418,3.747665307,0.0002241,DB0957010019211_,8.403417006,0.871609066,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ixazomib,DB09570
,1409629,DB09570,10061428,61,3840,55,3880,0.575210294,1.12062711,0.763296749,1.648571689,0.7246849,DB0957010061428_,0.322018339,0.113888449,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,ixazomib,DB09570
,1409909,DB09570,10013709,88,3813,100,3835,0.417671978,0.885091638,0.654544005,1.195100131,0.586740844,DB0957010013709_,0.533172048,-0.122064093,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,1409911,DB09570,10016322,44,3857,31,3904,0.132110521,1.436577514,0.884799906,2.358589135,0.258824958,DB0957010016322_,1.351603285,0.362263558,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,1410205,DB09331,10003988,51,2034,40,2389,0.070420648,1.497378998,0.966014697,2.335364446,0.162034993,DB0933110003988_,1.819942959,0.403716245,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,daratumumab,DB09331
,1410858,DB11362,10005734,105,6378,34,2135,0.921643875,1.033784343,0.693776994,1.575186415,0.965386517,DB1136210005734_,0.035226722,0.033226189,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,selexipag,DB11362
,1410970,DB00319,10077361,18,1374,34,1819,0.259315242,0.700948573,0.371012789,1.282741019,0.42043555,DB0031910077361_,0.86646408,-0.355320757,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,piperacillin,DB00319
,1410972,DB09029,10023003,44,11300,21,7249,0.308720734,1.344083706,0.781549819,2.381897809,0.476034641,DB0902910023003_,0.742264653,0.295712521,NA,10023003,Irritable bowel syndrome,10017947,Gastrointestinal disorders,Gastr,secukinumab,DB09029
,1410992,DB11362,10012735,1661,4822,525,1644,0.198987414,1.078663163,0.962257907,1.210202281,0.347834287,DB1136210012735_,1.0560291,0.075722462,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1410993,DB11362,10013968,1654,4829,526,1643,0.25314319,1.069868806,0.954436004,1.200282145,0.413540631,DB1136210013968_,0.882999508,0.06753603,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1410994,DB11362,10027599,199,6284,50,2119,0.074631279,1.342011839,0.975664785,1.876019123,0.169220028,DB1136210027599_,1.776555469,0.29416986,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1410995,DB11362,10028813,1545,4938,338,1831,1.47301488361535e-16,1.694821115,1.487432713,1.934836588,1.08151386077736e-14,DB1136210028813_,32.15782952,0.527577198,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1410996,DB11362,10030095,241,6242,87,2082,0.558842719,0.923964682,0.716339891,1.200823486,0.711730622,DB1136210030095_,0.340055779,-0.079081431,NA,10030095,Oedema,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1410997,DB11362,10047700,714,5769,123,2046,2.18285851755604e-14,2.058577287,1.68590696,2.530262656,1.22468380221901e-12,DB1136210047700_,27.42833843,0.722015107,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1411004,DB11362,10028810,257,6226,66,2103,0.049819577,1.315222445,0.995073057,1.759077978,0.12469807,DB1136210028810_,2.081859907,0.274005811,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,selexipag,DB11362
,1411112,DB09029,10025421,39,11305,39,7231,0.048789123,0.639665109,0.399279164,1.024756968,0.122772687,DB0902910025421_,2.097420707,-0.446810508,NA,10025421,Macule,10040785,Skin and subcutaneous tissue disorders,Skin,secukinumab,DB09029
,1411564,DB09570,10047700,180,3721,87,3848,3.56087943104393e-09,2.139391883,1.64033562,2.807642789,8.84666501370412e-08,DB0957010047700_,16.24064019,0.760521622,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,ixazomib,DB09570
,1411677,DB09145,10022086,35,964,17,451,0.880640423,0.963245674,0.51887317,1.85424286,0.950087484,DB0914510022086_,0.05120121,-0.037446787,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,water,DB09145
,1411960,DB11362,10013573,769,5714,217,1952,0.019138211,1.210571193,1.030608721,1.426299434,0.059698319,DB1136210013573_,2.818451422,0.191092309,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1411961,DB11362,10021097,529,5954,185,1984,0.588714333,0.95283543,0.79806691,1.141424164,0.735582809,DB1136210021097_,0.307092157,-0.048313076,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,selexipag,DB11362
,1411962,DB11362,10033371,893,5590,224,1945,2.84654357499536e-05,1.387079693,1.18562828,1.627612431,0.000270945,DB1136210033371_,8.213595563,0.327200597,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1411963,DB11362,10035664,628,5855,182,1987,0.073824287,1.170976973,0.983282973,1.3996347,0.167911685,DB1136210035664_,1.784317124,0.15783842,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,selexipag,DB11362
,1411965,DB11362,10038695,122,6361,51,2118,0.183854421,0.79652246,0.567659929,1.131567201,0.32877158,DB1136210038695_,1.112392056,-0.227499952,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1412000,DB00316,10077361,84,65390,72,36881,0.009663897,0.658051836,0.474446586,0.914620396,0.03463297,DB0031610077361_,3.36294915,-0.418471572,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,1412003,DB00959,10077361,53,8025,61,4941,0.000946695,0.535000307,0.362451333,0.7874019,0.005263934,DB0095910077361_,5.246876599,-0.625487959,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,methylprednisolone,DB00959
,1412114,DB09570,10020937,45,3856,32,3903,0.137167278,1.423319964,0.88263614,2.319384646,0.265770449,DB0957010020937_,1.325122316,0.352992145,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,ixazomib,DB09570
,1412312,DB09303,10020937,163,26068,116,18843,0.951494075,1.015715633,0.79497707,1.301125829,0.989653236,DB0930310020937_,0.010400663,0.015593421,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1412489,DB00704,10027599,50,4306,33,5161,0.007791862,1.815862703,1.14464259,2.915323642,0.029152244,DB0070410027599_,3.535223397,0.596560673,NA,10027599,Migraine,10029205,Nervous system disorders,Nerv,naltrexone,DB00704
,1412860,DB09292,10008190,47,4482,104,8158,0.30437495,0.822614663,0.568891741,1.174135556,0.471024968,DB0929210008190_,0.752844177,-0.195267398,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,1412952,DB11362,10033433,861,5622,272,1897,0.397772516,1.068092302,0.921531474,1.240645094,0.567460004,DB1136210033433_,0.566585009,0.065874162,NA,10033433,Pain in jaw,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1413393,DB09292,10067482,97,4432,200,8062,0.326666327,0.882229384,0.683050823,1.133235314,0.495078566,DB0929210067482_,0.70303881,-0.125303184,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,1413514,DB00091,10077361,24,5486,48,2622,3.30554110773497e-09,0.239019311,0.139685496,0.398977169,8.26699790835524e-08,DB0009110077361_,16.30840931,-1.431210932,male,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,cyclosporine,DB00091
,1413516,DB00635,10077361,113,32940,124,23670,0.0011984,0.654852796,0.502672729,0.852371346,0.006401779,DB0063510077361_,5.051179324,-0.423344808,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,1413819,DB11362,10008469,202,6281,43,2126,0.005537651,1.589922964,1.134590998,2.273077615,0.022197049,DB1136210008469_,3.807795924,0.463685565,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1414299,DB09570,10000087,51,3850,26,3909,0.004015169,1.991416709,1.215826715,3.334724777,0.017132907,DB0957010000087_,4.066754266,0.6888463,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,ixazomib,DB09570
,1414301,DB09570,10010774,114,3787,121,3814,0.740590635,0.948853828,0.725159682,1.240935752,0.851047056,DB0957010010774_,0.161287857,-0.05250052,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,ixazomib,DB09570
,1414306,DB09570,10048959,112,3789,82,3853,0.02894129,1.388859817,1.031399924,1.876691563,0.08233811,DB0957010048959_,2.496921217,0.328483135,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,1414765,DB00682,10077107,100,19359,22,16342,1.96838720523753e-10,3.836846319,2.398830842,6.39855608,6.12659060860491e-09,DB0068210077107_,18.91062742,1.344650758,female,10077107,Complication associated with device,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,1416075,DB11581,10012735,60,1693,86,2674,0.604737126,1.101912512,0.774357044,1.559603548,0.747989053,DB1158110012735_,0.290366936,0.097047318,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,venetoclax,DB11581
,1417974,DB00112,10076308,123,5810,106,3985,0.089476798,0.795913086,0.606812561,1.045351365,0.194435981,DB0011210076308_,1.637652318,-0.228265288,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,bevacizumab,DB00112
,1418468,DB00331,10077692,51,24895,25,20727,0.028711658,1.698433341,1.032697913,2.861730287,0.081853136,DB0033110077692_,2.502828656,0.529706262,NA,10077692,Liver function test increased,10022891,Investigations,Inv,metformin,DB00331
,1418469,DB00678,10077692,35,15564,21,10703,0.684131604,1.146082646,0.648457446,2.073260913,0.809088624,DB0067810077692_,0.211846821,0.136349732,NA,10077692,Liver function test increased,10022891,Investigations,Inv,losartan,DB00678
,1419136,DB00203,10067973,48,13830,16,8922,0.020713978,1.935301863,1.079028902,3.653490764,0.063535434,DB0020310067973_,2.756157517,0.660263316,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,sildenafil,DB00203
,1419790,DB08931,10074300,68,6509,16,2430,0.108622115,1.586642022,0.908200167,2.937070107,0.223967076,DB0893110074300_,1.496256218,0.461619847,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,riociguat,DB08931
,1420979,DB09128,10019211,40,1324,11,559,0.275320044,1.53498739,0.766027662,3.341756661,0.438646343,DB0912810019211_,0.824061788,0.428522166,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,brexpiprazole,DB09128
,1422144,DB09303,10037855,66,26165,55,18904,0.461004025,0.866995386,0.596667448,1.264095683,0.628293753,DB0930310037855_,0.464747462,-0.142721625,NA,10037855,Rash erythematous,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1422149,DB09303,10037884,169,26062,116,18843,0.71797749,1.05335291,0.82609415,1.346970828,0.833478562,DB0930310037884_,0.182147298,0.051978324,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1422470,DB09292,10007559,65,4464,112,8150,0.751654908,1.059562343,0.766492534,1.45446121,0.859795868,DB0929210007559_,0.151060281,0.057855939,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,sacubitril,DB09292
,1422760,DB09128,10013709,51,1313,31,539,0.106944844,0.67550214,0.418798721,1.105072737,0.221549754,DB0912810013709_,1.50710809,-0.392298954,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,brexpiprazole,DB09128
,1423050,DB00047,10070608,46,9239,43,8475,1,0.981303035,0.632577315,1.524923934,1,DB0004710070608_,0,-0.018873963,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,insulin glargine,DB00047
,1423452,DB09292,10003658,63,4466,110,8152,0.810338282,1.045408324,0.752829795,1.441066187,0.897944669,DB0929210003658_,0.107646829,0.044407549,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,sacubitril,DB09292
,1424064,DB06605,10052264,42,14031,15,13018,0.001239059,2.597597307,1.410571383,5.045133619,0.0065656,DB0660510052264_,5.025911369,0.954586905,NA,10052264,Catheter site erythema,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,1424702,DB09570,10047895,50,3851,49,3886,0.919631572,1.029685024,0.678473462,1.563439439,0.964404362,DB0957010047895_,0.03624461,0.029252953,NA,10047895,Weight decreased,10022891,Investigations,Inv,ixazomib,DB09570
,1425547,DB08895,10037162,82,28032,30,6616,0.052962899,0.645120539,0.419537057,1.016451939,0.130575416,DB0889510037162_,2.035804316,-0.438318097,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,tofacitinib,DB08895
,1425613,DB00958,10000880,41,4553,31,2554,0.218589,0.741954211,0.452798306,1.226895653,0.371788007,DB0095810000880_,0.98943146,-0.298467748,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,carboplatin,DB00958
,1426519,DB05829,10013709,67,1539,10,199,0.714027243,0.866430497,0.433954101,1.920243955,0.830414853,DB0582910013709_,0.18582988,-0.143373384,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,parathyroid hormone,DB05829
,1426908,DB09029,10040047,35,11309,30,7240,0.253065233,0.746923814,0.445039273,1.260621522,0.413459805,DB0902910040047_,0.883194976,-0.291792088,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,secukinumab,DB09029
,1428575,DB09128,10044565,43,1321,20,550,0.675256026,0.89521379,0.509875785,1.621972987,0.803126907,DB0912810044565_,0.219242536,-0.110692717,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,brexpiprazole,DB09128
,1429036,DB09128,10042458,42,1322,24,546,0.217763558,0.722891662,0.423047513,1.261077831,0.370900057,DB0912810042458_,0.991822642,-0.324495913,NA,10042458,Suicidal ideation,10037175,Psychiatric disorders,Psych,brexpiprazole,DB09128
,1429625,DB09303,10040844,41,26190,19,18940,0.116912618,1.560521976,0.885121792,2.847658936,0.236497092,DB0930310040844_,1.441819367,0.445020365,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1429684,DB09303,10010264,39,26192,23,18936,0.520012348,1.225897785,0.71389659,2.150674263,0.679146897,DB0930310010264_,0.386917832,0.203673461,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1429698,DB09303,10013786,67,26164,35,18924,0.131887782,1.384561148,0.906394549,2.148433389,0.258465636,DB0930310013786_,1.352992531,0.325383229,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1429794,DB09303,10024909,75,26156,199,18760,8.18734501587234e-25,0.270322882,0.204274628,0.354495371,1.23326282946822e-22,DB0930310024909_,50.44720868,-1.308138177,male,10024909,Low density lipoprotein decreased,10022891,Investigations,Inv,evolocumab,DB09303
,1430195,DB00381,10037162,75,29285,46,22841,0.232963203,1.27166,0.86905137,1.878479449,0.389494501,DB0038110037162_,0.942905532,0.240323133,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,amlodipine,DB00381
,1431628,DB00207,10077692,18,9062,45,5410,5.74720033088533e-08,0.238825313,0.129958267,0.421379331,1.09467507751682e-06,DB0020710077692_,13.72505297,-1.432022904,male,10077692,Liver function test increased,10022891,Investigations,Inv,azithromycin,DB00207
,1431630,DB00635,10077692,108,32945,60,23734,0.117177559,1.296736465,0.936778091,1.809796711,0.236887567,DB0063510077692_,1.440169651,0.259850697,NA,10077692,Liver function test increased,10022891,Investigations,Inv,prednisone,DB00635
,1432087,DB00051,10077692,223,25508,47,11373,7.87630271525208e-07,2.115427439,1.537279545,2.965100956,1.16047430981166e-05,DB0005110077692_,11.36409666,0.749256891,NA,10077692,Liver function test increased,10022891,Investigations,Inv,adalimumab,DB00051
,1432323,DB09292,10016807,78,4451,171,8091,0.18124384,0.829205397,0.624461917,1.092954358,0.325431678,DB0929210016807_,1.122602739,-0.18728739,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,sacubitril,DB09292
,1432501,DB09331,10046571,41,2044,25,2404,0.012290305,1.928543758,1.140638604,3.321422857,0.041951908,DB0933110046571_,3.171231367,0.656765188,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,daratumumab,DB09331
,1432506,DB09331,10069339,32,2053,34,2395,0.711089725,1.097939449,0.653397675,1.841075,0.827730988,DB0933110069339_,0.189067072,0.093435195,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,daratumumab,DB09331
,1432507,DB09292,10010253,22,4507,36,8226,0.681767968,1.115362649,0.624255251,1.950668854,0.8075468,DB0929210010253_,0.213754269,0.109179598,NA,10010253,Concomitant disease aggravated,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,1432683,DB00019,10069217,71,18941,31,9498,0.599144138,1.148471144,0.742664967,1.813765602,0.743836372,DB0001910069217_,0.295934199,0.138431618,NA,10069217,Needle issue,10077536,Product issues,Prod,pegfilgrastim,DB00019
,1432708,DB00019,10073317,1641,17371,520,9009,1.31035057247001e-22,1.636627176,1.47703019,1.815646124,1.73514180339417e-20,DB0001910073317_,45.50061272,0.492637524,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,1432893,DB00482,10076573,45,8214,13,3058,0.462887732,1.288654777,0.682014364,2.607618043,0.630116374,DB0048210076573_,0.461850756,0.253598866,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,celecoxib,DB00482
,1434035,DB00169,10077605,51,38640,8,18167,0.001857121,2.997225463,1.411541312,7.314981625,0.009155853,DB0016910077605_,4.69336193,1.097687015,female,10077605,Anal incontinence,10017947,Gastrointestinal disorders,Gastr,cholecalciferol,DB00169
,1434219,DB09331,10047700,49,2036,37,2392,0.04903929,1.55571513,0.990141944,2.462932051,0.123179773,DB0933110047700_,2.094110418,0.441935331,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,daratumumab,DB09331
,1434301,DB09331,10016256,109,1976,110,2319,0.297403978,1.162872843,0.877725017,1.54050174,0.463313888,DB0933110016256_,0.769350511,0.150893532,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,daratumumab,DB09331
,1434519,DB09303,10013971,22,26209,35,18924,0.004358324,0.453858722,0.253539601,0.795957195,0.018307399,DB0930310013971_,4.000449965,-0.789969314,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1434641,DB09570,10035528,97,3804,102,3833,0.774445195,0.958222928,0.715400104,1.282778838,0.877029445,DB0957010035528_,0.131214712,-0.042674827,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,ixazomib,DB09570
,1435187,DB00264,10077692,43,29564,38,24854,0.824408033,0.951276981,0.600272114,1.512938905,0.906981582,DB0026410077692_,0.097633136,-0.049950006,NA,10077692,Liver function test increased,10022891,Investigations,Inv,metoprolol,DB00264
,1436511,DB11362,10016256,869,5614,229,1940,0.000523925,1.311343639,1.121752916,1.537298248,0.003208241,DB1136210016256_,5.742032409,0.27105229,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1436513,DB11362,10033425,811,5672,275,1894,0.851525545,0.984764864,0.84926272,1.144309175,0.927035659,DB1136210033425_,0.075763247,-0.015352383,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1437353,DB00338,10077361,31,33643,29,22243,0.188260952,0.706764396,0.411923425,1.215813166,0.334353996,DB0033810077361_,1.09555498,-0.347057913,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,1437355,DB00404,10077361,19,19873,37,9825,5.32565944166558e-07,0.253874933,0.137840947,0.45323873,8.20685824297173e-06,DB0040410077361_,11.71054038,-1.370913522,male,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,1437700,DB00065,10077692,71,9393,8,4949,1.07832621745694e-06,4.675106628,2.246182683,11.25440876,1.52879205101702e-05,DB0006510077692_,11.08844755,1.542251971,female,10077692,Liver function test increased,10022891,Investigations,Inv,infliximab,DB00065
,1437953,DB00559,10077692,80,9579,46,3260,0.007228702,0.591901781,0.405865945,0.87216805,0.027459562,DB0055910077692_,3.595040816,-0.524414568,NA,10077692,Liver function test increased,10022891,Investigations,Inv,bosentan,DB00559
,1438450,DB09303,10024855,33,26198,26,18933,0.792243014,0.917261259,0.531884808,1.597548405,0.88743507,DB0930310024855_,0.119419921,-0.086362941,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1438491,DB00158,10077692,47,16768,22,8082,1,1.029733352,0.607862662,1.795475421,1,DB0015810077692_,0,0.029299888,NA,10077692,Liver function test increased,10022891,Investigations,Inv,folic acid,DB00158
,1438492,DB00169,10077692,93,38598,42,18133,0.926407142,1.040236286,0.714900448,1.536143741,0.968728294,DB0016910077692_,0.031771104,0.039447885,NA,10077692,Liver function test increased,10022891,Investigations,Inv,cholecalciferol,DB00169
,1438495,DB00480,10077692,49,67379,33,67629,0.077850747,1.490345619,0.93916891,2.392540597,0.174733744,DB0048010077692_,1.744491926,0.399008052,NA,10077692,Liver function test increased,10022891,Investigations,Inv,lenalidomide,DB00480
,1438498,DB01373,10077692,44,22676,14,7367,1,1.021060081,0.548818819,2.018712272,1,DB0137310077692_,0,0.020841383,NA,10077692,Liver function test increased,10022891,Investigations,Inv,calcium,DB01373
,1438926,DB00028,10022093,61,13397,10,5605,0.00376844,2.55196057,1.296400218,5.590896059,0.016254686,DB0002810022093_,4.119374052,0.936861915,NA,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,1439561,DB09331,10016288,20,2065,41,2388,0.038341545,0.564175931,0.312067385,0.988959435,0.102325055,DB0933110016288_,2.279600714,-0.572389142,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,daratumumab,DB09331
,1439562,DB09331,10061818,26,2059,33,2396,0.793478041,0.916819996,0.524732273,1.586540728,0.888018693,DB0933110061818_,0.118762485,-0.086844123,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,daratumumab,DB09331
,1440695,DB08895,10076308,97,28017,30,6616,0.212848188,0.763533721,0.501917386,1.192578042,0.364836708,DB0889510076308_,1.008305401,-0.269797989,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,1440973,DB09029,10010305,34,11310,16,7254,0.383967084,1.362908959,0.731391402,2.646385665,0.553989175,DB0902910010305_,0.590610132,0.309621356,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,secukinumab,DB09029
,1441041,DB00704,10013654,24,4332,62,5132,0.000995525,0.458629037,0.273241396,0.746966513,0.005480077,DB0070410013654_,5.20663608,-0.779513593,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,1441915,DB08895,10036495,97,28017,28,6618,0.361616936,0.818317004,0.53214307,1.295834315,0.531441735,DB0889510036495_,0.63216171,-0.200505482,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,1442006,DB09292,10049848,27,4502,46,8216,0.806482158,1.071169239,0.639409534,1.762462841,0.895391067,DB0929210049848_,0.11049471,0.068750798,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,1442019,DB09292,10020937,23,4506,38,8224,0.689707192,1.104667496,0.627459074,1.905213312,0.812888491,DB0929210020937_,0.207161336,0.099544381,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,1443555,DB09343,10013709,77,1442,117,1766,0.15824219,0.806042518,0.591389244,1.093559068,0.295107734,DB0934310013709_,1.22041479,-0.215618786,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,tipiracil,DB09343
,1445687,DB00193,10017076,56,19264,9,8693,0.001858424,2.807733445,1.377520239,6.459743206,0.009159233,DB0019310017076_,4.692992854,1.032377555,female,10017076,Fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,1446358,DB09303,10065154,81,26150,74,18885,0.165543777,0.790504773,0.569257605,1.099109632,0.304863601,DB0930310065154_,1.187890811,-0.235083584,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,evolocumab,DB09303
,1447149,DB00381,10077361,50,29310,31,22856,0.37011178,1.257739012,0.787579187,2.03752784,0.539747838,DB0038110077361_,0.616653216,0.229315674,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,1447232,DB00087,10048393,40,1329,15,732,0.252831299,1.468522443,0.78730709,2.882143211,0.413146666,DB0008710048393_,0.883952625,0.384256754,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,alemtuzumab,DB00087
,1448797,DB00005,10016062,38,128044,18,42401,0.216766761,0.699083585,0.389253986,1.301376676,0.369585464,DB0000510016062_,0.99537327,-0.357984966,NA,10016062,Facial paralysis,10029205,Nervous system disorders,Nerv,etanercept,DB00005
,1449212,DB09292,10046571,43,4486,17,8245,1.30980773591483e-08,4.648258194,2.592950429,8.704122045,2.8642509433046e-07,DB0929210046571_,15.06578879,1.536492567,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,sacubitril,DB09292
,1449255,DB01225,10077692,39,5005,60,4580,0.011465099,0.59484231,0.386133214,0.907011188,0.03972059,DB0122510077692_,3.22588558,-0.519458934,NA,10077692,Liver function test increased,10022891,Investigations,Inv,enoxaparin,DB01225
,1449387,DB01118,10077361,23,3040,41,4668,0.60933716,0.86143941,0.492360496,1.473065926,0.75180301,DB0111810077361_,0.285280944,-0.149150556,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,amiodarone,DB01118
,1450282,DB00316,10061494,33,65441,30,36923,0.065724573,0.62061351,0.36691599,1.053705391,0.153664257,DB0031610061494_,1.872985206,-0.477046758,NA,10061494,Rhinovirus infection,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,1450330,DB09303,10029223,33,26198,21,18938,0.681323898,1.135913799,0.637713496,2.066658135,0.807380174,DB0930310029223_,0.213960626,0.127437437,NA,10029223,Neuralgia,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1452313,DB05351,10064848,356,2367,215,916,3.50702800591148e-06,0.64085846,0.530290363,0.775628543,4.33085417596351e-05,DB0535110064848_,10.04716067,-0.444946658,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,dexlansoprazole,DB05351
,1454304,DB00254,10054112,48,5887,29,3359,0.812701158,0.944413349,0.582296623,1.556313063,0.899275924,DB0025410054112_,0.106165369,-0.057191339,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,doxycycline,DB00254
,1454308,DB13867,10054112,94,4456,48,2506,0.658864839,1.101340872,0.766980107,1.599297226,0.791655557,DB1386710054112_,0.233628884,0.096528412,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,fluticasone,DB13867
,1454827,DB00203,10077692,72,13806,38,8900,0.329667925,1.221399548,0.812694441,1.861974294,0.498350668,DB0020310077692_,0.696451297,0.199997372,NA,10077692,Liver function test increased,10022891,Investigations,Inv,sildenafil,DB00203
,1454830,DB00682,10077692,45,19414,23,16341,0.051695167,1.64680154,0.975102081,2.85297268,0.128237776,DB0068210077692_,2.053869111,0.498834946,NA,10077692,Liver function test increased,10022891,Investigations,Inv,warfarin,DB00682
,1454837,DB09128,10012378,54,1310,30,540,0.220904339,0.742093594,0.46067956,1.215428779,0.374571076,DB0912810012378_,0.981973705,-0.298279906,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,brexpiprazole,DB09128
,1455055,DB06212,10076573,35,639,21,551,0.218244787,1.436727718,0.802480656,2.630481472,0.371418855,DB0621210076573_,0.990424864,0.36236811,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,tolvaptan,DB06212
,1455228,DB00635,10073317,101,32952,26,23768,4.86109674580291e-07,2.80184474,1.805248898,4.495313739,7.56506382258315e-06,DB0063510073317_,11.79196977,1.030278036,female,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,1455683,DB09107,10025482,32,1183,26,977,1,1.016444841,0.582454254,1.788964443,1,DB0910710025482_,0,0.016311089,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,methoxy polyethylene glycol-epoetin beta,DB09107
,1455892,DB08931,10053762,80,6497,30,2416,1,0.991637979,0.642477948,1.567482228,1,DB0893110053762_,0,-0.008397179,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,riociguat,DB08931
,1456007,DB09035,10003445,20,4706,32,6658,0.778108771,0.884223716,0.478658522,1.596470035,0.879072925,DB0903510003445_,0.128887421,-0.123045176,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,nivolumab,DB09035
,1456016,DB11362,10037660,226,6257,73,2096,0.838685128,1.037096697,0.789246525,1.375978818,0.917178281,DB1136210037660_,0.086453408,0.036425172,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1456018,DB11362,10064687,40,6443,12,2157,0.872746485,1.115924807,0.572678515,2.341128159,0.944446833,DB1136210064687_,0.057155884,0.109683484,NA,10064687,Device related infection,10021881,Infections and infestations,Infec,selexipag,DB11362
,1457144,DB08932,10077107,92,19351,30,6567,0.917098756,1.040735741,0.68185805,1.629949792,0.963120412,DB0893210077107_,0.037576836,0.039927906,NA,10077107,Complication associated with device,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,1458030,DB08865,10061309,133,1078,101,870,0.676762573,1.062739306,0.801373838,1.412503376,0.803963008,DB0886510061309_,0.218202021,0.060849825,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,crizotinib,DB08865
,1458155,DB09128,10016322,42,1322,24,546,0.217763558,0.722891662,0.423047513,1.261077831,0.370900057,DB0912810016322_,0.991822642,-0.324495913,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,brexpiprazole,DB09128
,1458394,DB09292,10048959,80,4449,138,8124,0.721065808,1.058561788,0.791448816,1.407900342,0.835495472,DB0929210048959_,0.179730351,0.056911183,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,1458811,DB09035,10046571,77,4649,54,6636,7.41796200668524e-05,2.035272363,1.415652039,2.943999808,0.000616834,DB0903510046571_,7.390911107,0.710629649,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,nivolumab,DB09035
,1459047,DB09302,10053425,49,2149,21,1526,0.065328014,1.65667952,0.970424384,2.921144813,0.152994591,DB0930210053425_,1.877352709,0.50481531,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1459107,DB09302,10011224,43,2155,36,1511,0.48863846,0.837541237,0.522584632,1.349331891,0.652187875,DB0930210011224_,0.427422606,-0.177284778,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,alirocumab,DB09302
,1459636,DB00480,10076573,43,67385,15,67647,0.000198363,2.877948465,1.567136123,5.576391037,0.001430835,DB0048010076573_,6.549497003,1.057077702,female,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,1459647,DB11362,10009033,77,6406,30,2139,0.500608649,0.857064204,0.553618876,1.357980452,0.662162759,DB1136210009033_,0.412243894,-0.154242446,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1459648,DB11362,10016825,354,6129,116,2053,0.869720887,1.022227968,0.821389068,1.279504856,0.942090076,DB1136210016825_,0.059654387,0.021984527,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,selexipag,DB11362
,1459649,DB11362,10021143,144,6339,69,2100,0.016064456,0.691404455,0.513086337,0.939227369,0.051982547,DB1136210021143_,2.956847255,-0.369030309,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1459651,DB11362,10064911,380,6103,136,2033,0.496001913,0.930764023,0.758076945,1.148074028,0.658355314,DB1136210064911_,0.418010502,-0.0717495,NA,10064911,Pulmonary arterial hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1459767,DB00451,10076869,64,47207,7,15412,0.002300293,2.985006196,1.367828295,7.723100962,0.010898025,DB0045110076869_,4.519173723,1.093601822,female,10076869,Product preparation error,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,1459827,DB05676,10076573,89,47040,27,25302,0.008274192,1.773007004,1.14109802,2.83864323,0.030597515,DB0567610076573_,3.486836473,0.572676977,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,apremilast,DB05676
,1459953,DB01183,10033371,31,528,19,529,0.111470385,1.633943883,0.881625679,3.102703104,0.228255292,DB0118310033371_,1.477290573,0.490996653,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,naloxone,DB01183
,1460050,DB09331,10013709,45,2040,42,2387,0.328786619,1.253608065,0.80115839,1.965085566,0.497418918,DB0933110013709_,0.698322715,0.226025846,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,daratumumab,DB09331
,1460093,DB09331,10008531,22,2063,52,2377,0.0045351,0.487557268,0.280948267,0.820221464,0.018890042,DB0933110008531_,3.969120352,-0.718347522,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,daratumumab,DB09331
,1460147,DB09035,10013709,52,4674,45,6645,0.016938997,1.642732956,1.078863897,2.509770997,0.054241522,DB0903510013709_,2.914308569,0.496361292,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,nivolumab,DB09035
,1460914,DB01390,10054112,27,1382,39,1478,0.262792421,0.740475866,0.433349526,1.24840275,0.424554321,DB0139010054112_,0.856715317,-0.300462237,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,sodium bicarbonate,DB01390
,1461045,DB09292,10008469,31,4498,46,8216,0.403105169,1.230922354,0.753391133,1.986583593,0.57287553,DB0929210008469_,0.557086811,0.20776377,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,1461861,DB08895,10023204,61,28053,7,6639,0.064588483,2.062252208,0.942105744,5.346434582,0.151733704,DB0889510023204_,1.885628245,0.72379869,NA,10023204,Joint dislocation,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,1463424,DB09292,10020751,56,4473,54,8208,0.000886986,1.902934713,1.283272137,2.823837567,0.004993454,DB0929210020751_,5.299627376,0.64339728,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,sacubitril,DB09292
,1464712,DB00051,10062262,55,25676,25,11395,0.903943982,0.976359286,0.597885515,1.636020532,0.957442354,DB0005110062262_,0.043489764,-0.023924639,NA,10062262,Spinal operation,10042613,Surgical and medical procedures,Surg,adalimumab,DB00051
,1465383,DB06212,10076309,41,633,37,535,0.814984236,0.93662045,0.576452937,1.526152216,0.90068368,DB0621210076309_,0.104601159,-0.065477149,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tolvaptan,DB06212
,1465448,DB00761,10061309,51,15256,21,8604,0.268540815,1.369635892,0.808692917,2.3987809,0.430967141,DB0076110061309_,0.84172343,0.314544932,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,potassium chloride,DB00761
,1465452,DB01006,10061309,379,5568,11,166,1,1.027196845,0.553030894,2.116295245,1,DB0100610061309_,0,0.026833582,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,letrozole,DB01006
,1465459,DB09073,10061309,1920,18340,71,719,0.709926979,1.060165137,0.825787543,1.379027074,0.827036771,DB0907310061309_,0.189906122,0.058424685,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,palbociclib,DB09073
,1465498,DB09029,10003553,38,11306,13,7257,0.060579331,1.876177833,0.97681291,3.841176021,0.144487793,DB0902910003553_,1.934560252,0.62923664,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,secukinumab,DB09029
,1465535,DB06626,10061309,44,644,94,1358,1,0.987054823,0.665332646,1.445793161,1,DB0662610061309_,0,-0.013029696,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,axitinib,DB06626
,1465868,DB00497,10077692,33,19234,24,16351,0.596689625,1.168894487,0.669910176,2.067787219,0.742050851,DB0049710077692_,0.298337506,0.156058419,NA,10077692,Liver function test increased,10022891,Investigations,Inv,oxycodone,DB00497
,1466201,DB09570,10060933,145,3756,113,3822,0.03679303,1.305684966,1.00956113,1.692103193,0.099164809,DB0957010060933_,2.310972072,0.266727781,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,1466601,DB00046,10074904,35,5424,22,4670,0.287014484,1.369709558,0.780016604,2.454731972,0.451814685,DB0004610074904_,0.794483173,0.314598716,NA,10074904,Accidental underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin lispro,DB00046
,1466723,DB09570,10023232,26,3875,31,3904,0.595493082,0.845005552,0.480916914,1.4736944,0.741141393,DB0957010023232_,0.299563858,-0.168412081,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,ixazomib,DB09570
,1467227,DB00688,10077361,58,6432,54,5324,0.567713062,0.889059899,0.601885955,1.315134391,0.718785089,DB0068810077361_,0.330192868,-0.117590668,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,1467310,DB00563,10076308,54,46592,32,15316,0.011731765,0.554740359,0.351664133,0.888131472,0.04043129,DB0056310076308_,3.208151285,-0.589255095,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,1467718,DB08895,10062355,60,28054,9,6637,0.222994275,1.57716666,0.777318113,3.617258043,0.377206031,DB0889510062355_,0.97496374,0.455629984,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,1467974,DB06186,10051076,43,2166,78,3568,0.637020031,0.908115075,0.608367003,1.339924826,0.774381848,DB0618610051076_,0.255690184,-0.096384174,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,ipilimumab,DB06186
,1468046,DB11362,10000087,288,6195,69,2100,0.010458771,1.41479062,1.079016667,1.876522103,0.036875761,DB1136210000087_,3.300200839,0.346981548,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1473409,DB00186,10077692,45,16856,20,9988,0.306493978,1.333220662,0.770759508,2.38474592,0.473500977,DB0018610077692_,0.747601302,0.287597565,NA,10077692,Liver function test increased,10022891,Investigations,Inv,lorazepam,DB00186
,1474719,DB09029,10016322,75,11269,53,7217,0.586570828,0.906274443,0.628262011,1.315395412,0.733754395,DB0902910016322_,0.309580918,-0.098413102,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,1474871,DB09303,10069217,61,26170,58,18901,0.137477581,0.759609568,0.521196733,1.108112717,0.266185276,DB0930310069217_,1.323562685,-0.274950704,NA,10069217,Needle issue,10077536,Product issues,Prod,evolocumab,DB09303
,1474970,DB09331,10033661,23,2062,31,2398,0.680882429,0.862861229,0.478801264,1.534051218,0.807023985,DB0933110033661_,0.21440189,-0.147501401,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,daratumumab,DB09331
,1475891,DB09331,10010774,30,2055,32,2397,0.797865804,1.093499682,0.639501793,1.865259454,0.890778357,DB0933110010774_,0.11565964,0.08938327,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,daratumumab,DB09331
,1476483,DB00695,10074414,55,27994,15,20513,0.00037099,2.686719136,1.496057284,5.121543914,0.002407177,DB0069510074414_,6.029300531,0.988320797,NA,10074414,Catheter management,10042613,Surgical and medical procedures,Surg,furosemide,DB00695
,1477003,DB08931,10037833,46,6531,17,2429,1,1.00636794,0.564724623,1.876239833,1,DB0893110037833_,0,0.00634775,NA,10037833,Rales,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,riociguat,DB08931
,1478059,DB00451,10077692,84,47187,25,15394,0.739529856,1.096143775,0.693936163,1.789273709,0.85016024,DB0045110077692_,0.16233043,0.091798362,NA,10077692,Liver function test increased,10022891,Investigations,Inv,levothyroxine,DB00451
,1478090,DB09292,10037423,18,4511,35,8227,0.886349915,0.937935965,0.499503596,1.70378913,0.952748725,DB0929210037423_,0.048404077,-0.064073599,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sacubitril,DB09292
,1478192,DB00009,10067482,48,1303,41,1510,0.16200217,1.35656605,0.869286583,2.125572586,0.300044182,DB0000910067482_,1.203825541,0.304956544,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,alteplase,DB00009
,1478254,DB09331,10037660,62,2023,69,2360,0.790478169,1.048248402,0.727687318,1.50726901,0.886497084,DB0933110037660_,0.120477443,0.047120583,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,daratumumab,DB09331
,1478255,DB09331,10047942,89,1996,85,2344,0.187963328,1.229551002,0.897342987,1.68570381,0.334005954,DB0933110047942_,1.09659646,0.206649064,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,daratumumab,DB09331
,1479165,DB09076,10011906,44,764,45,565,0.150905478,0.723273084,0.459311915,1.138223876,0.285176921,DB0907610011906_,1.254645518,-0.323968419,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,umeclidinium,DB09076
,1479714,DB09029,10069217,76,11268,58,7212,0.328845673,0.838690236,0.587290837,1.203167785,0.497465311,DB0902910069217_,0.698229451,-0.175913847,NA,10069217,Needle issue,10077536,Product issues,Prod,secukinumab,DB09029
,1480261,DB00972,10066901,217,2287,100,1079,0.89981871,1.023793979,0.794864676,1.325555357,0.956571579,DB0097210066901_,0.044399659,0.023515314,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,azelastine,DB00972
,1480751,DB01234,10076573,49,31576,21,32867,0.000457612,2.428774532,1.429108372,4.26518876,0.002868036,DB0123410076573_,5.854127903,0.887386822,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,1481464,DB09303,10052140,41,26190,9,18950,0.000465908,3.296094907,1.577538893,7.715266439,0.002912685,DB0930310052140_,5.838680008,1.192738406,female,10052140,Eye pruritus,10015919,Eye disorders,Eye,evolocumab,DB09303
,1481466,DB09303,10063910,77,26154,43,18916,0.194791821,1.295122229,0.880109304,1.928140493,0.342756929,DB0930310063910_,1.070733746,0.258605076,NA,10063910,Sleep disorder due to a general medical condition,10037175,Psychiatric disorders,Psych,evolocumab,DB09303
,1481570,DB09303,10074903,212,26019,188,18771,0.04179446,0.813541326,0.664695425,0.996304392,0.109315627,DB0930310074903_,2.213515923,-0.206358553,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,1481584,DB09303,10022079,35,26196,27,18932,0.798210879,0.936846682,0.550714944,1.609870887,0.890968552,DB0930310022079_,0.115446147,-0.065235636,NA,10022079,Injection site irritation,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1482474,DB00181,10077107,58,9798,63,5808,0.001237161,0.545774336,0.374745421,0.793579135,0.006557574,DB0018110077107_,5.027134566,-0.605549692,NA,10077107,Complication associated with device,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,1483036,DB00864,10048983,13,6856,41,8351,0.002261636,0.386245737,0.18974657,0.735995097,0.010754792,DB0086410048983_,4.532403876,-0.951281487,NA,10048983,Cytomegalovirus colitis,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,1483514,DB00213,10077692,42,18853,35,13386,0.489407911,0.852031073,0.530757063,1.3754209,0.65276739,DB0021310077692_,0.426534431,-0.160132283,NA,10077692,Liver function test increased,10022891,Investigations,Inv,pantoprazole,DB00213
,1483728,DB09292,10047571,38,4491,52,8210,0.184970508,1.335847309,0.854011678,2.072842496,0.330116092,DB0929210047571_,1.108310892,0.289565779,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,sacubitril,DB09292
,1483976,DB09302,10043414,33,2165,17,1530,0.314673352,1.371711383,0.739293834,2.635871615,0.482288341,DB0930210043414_,0.729213125,0.316059145,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,1484427,DB09331,10013573,44,2041,33,2396,0.064459398,1.565071883,0.96997989,2.547556818,0.151474254,DB0933110013573_,1.887339608,0.447931754,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,daratumumab,DB09331
,1484444,DB09331,10035664,124,1961,178,2251,0.072924108,0.799689809,0.625497491,1.019905983,0.166404217,DB0933110035664_,1.79333541,-0.223531365,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,daratumumab,DB09331
,1484461,DB00331,10061309,45,24901,18,20734,0.00754693,2.081572781,1.180786398,3.822142744,0.028424865,DB0033110061309_,3.560491001,0.733123753,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,metformin,DB00331
,1485131,DB01413,10077361,23,1197,31,1628,1,1.009079969,0.558796146,1.797843364,1,DB0141310077361_,0,0.009038994,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,cefepime,DB01413
,1485388,DB09078,10033425,23,770,35,1021,0.686643842,0.871434044,0.487263735,1.531181319,0.811001522,DB0907810033425_,0.209485348,-0.137615098,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,lenvatinib,DB09078
,1486641,DB00695,10077692,64,27985,44,20484,0.770829729,1.064684823,0.713760473,1.600976704,0.874483718,DB0069510077692_,0.134121604,0.062678815,NA,10077692,Liver function test increased,10022891,Investigations,Inv,furosemide,DB00695
,1486642,DB00761,10077692,50,15257,21,8604,0.268502869,1.342693312,0.79125769,2.3553064,0.430942554,DB0076110077692_,0.841780483,0.294677531,NA,10077692,Liver function test increased,10022891,Investigations,Inv,potassium chloride,DB00761
,1487864,DB09570,10029354,36,3865,36,3899,1,1.008796381,0.616220408,1.651471602,1,DB0957010029354_,0,0.008757918,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,ixazomib,DB09570
,1490007,DB11362,10043607,49,6434,22,2147,0.270835119,0.74325942,0.43977793,1.294081175,0.433524213,DB1136210043607_,0.835807629,-0.296710143,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,selexipag,DB11362
,1490330,DB09570,10043607,34,3867,56,3879,0.025573558,0.609068529,0.384655552,0.951603108,0.074768475,DB0957010043607_,2.593358937,-0.495824491,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,ixazomib,DB09570
,1490708,DB00704,10022095,970,3386,1020,4174,0.001708127,1.172272014,1.060508897,1.295737557,0.008540637,DB0070410022095_,4.762919741,0.158943758,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,1490743,DB08895,10077692,315,27799,62,6584,0.21058693,1.203308013,0.912592792,1.608784524,0.361877448,DB0889510077692_,1.016449665,0.185074441,NA,10077692,Liver function test increased,10022891,Investigations,Inv,tofacitinib,DB08895
,1491189,DB09303,10008190,80,26151,67,18892,0.402701429,0.862596212,0.615363649,1.212458017,0.572471988,DB0930310008190_,0.557791475,-0.147808586,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1491370,DB00864,10077361,70,6799,79,8313,0.679231171,1.083381029,0.77264295,1.516402381,0.805885679,DB0086410077361_,0.215813384,0.080086733,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,tacrolimus,DB00864
,1491417,DB00635,10016062,33,33020,22,23772,0.891405162,1.079906114,0.610807169,1.94483305,0.954908289,DB0063510016062_,0.046139976,0.076874106,NA,10016062,Facial paralysis,10029205,Nervous system disorders,Nerv,prednisone,DB00635
,1491560,DB11362,10017577,147,6336,46,2123,0.737309866,1.07075671,0.761049173,1.531181967,0.848575425,DB1136210017577_,0.164196306,0.068365604,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1491561,DB11362,10028411,793,5690,252,1917,0.469625633,1.060179357,0.910078853,1.237945524,0.635938155,DB1136210028411_,0.452653961,0.058438099,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1491999,DB09292,10001760,50,4479,19,8243,4.19901679107558e-10,4.842386737,2.800695696,8.708195441,1.2457241123411e-08,DB0929210001760_,18.20096377,1.577407727,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,sacubitril,DB09292
,1493686,DB00316,10077107,45,65429,25,36928,1,1.015916704,0.609682356,1.729137115,1,DB0031610077107_,0,0.015791362,NA,10077107,Complication associated with device,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,1494852,DB09292,10009033,14,4515,39,8223,0.196119476,0.653806886,0.32753353,1.232438563,0.344389914,DB0929210009033_,1.065980791,-0.424943252,NA,10009033,Chronic obstructive pulmonary disease,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,sacubitril,DB09292
,1495047,DB00635,10077512,41,33012,55,23739,0.002556717,0.53607603,0.348665552,0.81833259,0.01186918,DB0063510077512_,4.433810124,-0.62347928,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,prednisone,DB00635
,1495331,DB00581,10054112,48,2065,31,2038,0.069733559,1.527980731,0.948515298,2.494064636,0.160827111,DB0058110054112_,1.827425334,0.42394708,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,lactulose,DB00581
,1496493,DB00169,10077361,36,38655,28,18147,0.059281145,0.603590574,0.358039237,1.02723493,0.142139558,DB0016910077361_,1.950945902,-0.504859168,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,1496496,DB00682,10077361,32,19427,33,16331,0.455242659,0.815167967,0.485073363,1.36830826,0.622777833,DB0068210077361_,0.473565432,-0.204361092,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,1497393,DB00355,10036790,19,1774,36,1227,0.000437314,0.365161926,0.196894691,0.657295442,0.00276118,DB0035510036790_,5.892097038,-1.00741439,male,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,aztreonam,DB00355
,1498519,DB09303,10057392,50,26181,37,18922,0.913844858,0.976664797,0.625533905,1.537347218,0.9614318,DB0930310057392_,0.039331647,-0.02361178,NA,10057392,Paranasal sinus hypersecretion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1498521,DB09303,10014020,56,26175,17,18942,0.001201859,2.383780996,1.364503655,4.377616946,0.006413467,DB0930310014020_,5.049355319,0.868687881,NA,10014020,Ear pain,10013993,Ear and labyrinth disorders,Ear,evolocumab,DB09303
,1499256,DB11581,10002034,34,1719,43,2717,0.346928798,1.249675317,0.769560275,2.01499466,0.516351374,DB1158110002034_,0.660967787,0.222883771,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,venetoclax,DB11581
,1499261,DB11581,10003549,34,1719,78,2682,0.062812568,0.680146965,0.438618233,1.035095793,0.148667628,DB1158110003549_,1.906042147,-0.385446379,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,venetoclax,DB11581
,1499427,DB00350,10053762,49,491,17,444,0.000530878,2.604314751,1.448310839,4.897868486,0.003239983,DB0035010053762_,5.732187312,0.957169589,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,minoxidil,DB00350
,1499875,DB09303,10042727,59,26172,12,18947,9.6069657258157e-06,3.559257737,1.892390393,7.27732154,0.000105019,DB0930310042727_,9.161365674,1.269552022,female,10042727,Swollen tongue,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,1501051,DB09331,10012735,102,1983,78,2351,0.004655294,1.550199714,1.135768681,2.122633591,0.019301901,DB0933110012735_,3.947551679,0.43838377,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,daratumumab,DB09331
,1501069,DB09331,10028813,81,2004,53,2376,0.000808171,1.811736036,1.258870111,2.626072251,0.004614983,DB0933110028813_,5.378447164,0.594285521,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,daratumumab,DB09331
,1501079,DB09331,10043554,27,2058,37,2392,0.531037146,0.848191322,0.494820109,1.436808834,0.687912749,DB0933110043554_,0.374093268,-0.164649053,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,daratumumab,DB09331
,1504342,DB09145,10019974,41,958,31,437,0.050869237,0.603522096,0.36386891,1.009894647,0.126649103,DB0914510019974_,2.066334984,-0.504972626,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,water,DB09145
,1504671,DB09303,10039674,36,26195,27,18932,0.898874226,0.96362524,0.568714094,1.650976121,0.956490275,DB0930310039674_,0.044484657,-0.037052815,NA,10039674,Sciatica,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1504672,DB09303,10054266,124,26107,116,18843,0.04899992,0.771549307,0.593677273,1.003264002,0.123124076,DB0930310054266_,2.094562684,-0.259354699,NA,10054266,Injection site discomfort,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1504736,DB09303,10072878,450,25781,298,18661,0.246882361,1.093049442,0.940910866,1.271198254,0.405987416,DB0930310072878_,0.901433115,0.088971443,NA,10072878,Device use error,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,1504738,DB09343,10003549,60,1459,61,1822,0.265841244,1.228247965,0.839560592,1.796402784,0.427954257,DB0934310003549_,0.848738965,0.205588736,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,tipiracil,DB09343
,1504740,DB09343,10047895,31,1488,30,1853,0.363748707,1.286700866,0.749617032,2.211420138,0.533317778,DB0934310047895_,0.628637825,0.252081474,NA,10047895,Weight decreased,10022891,Investigations,Inv,tipiracil,DB09343
,1505250,DB09078,10013573,21,772,31,1025,0.77713122,0.899444475,0.487139137,1.630524168,0.878512755,DB0907810013573_,0.129524852,-0.105977956,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lenvatinib,DB09078
,1505256,DB09078,10042128,40,753,44,1012,0.369578876,1.221638881,0.767294854,1.940238196,0.539223489,DB0907810042128_,0.617625158,0.200193302,NA,10042128,Stomatitis,10017947,Gastrointestinal disorders,Gastr,lenvatinib,DB09078
,1505682,DB09303,10050256,36,26195,27,18932,0.898874226,0.96362524,0.568714094,1.650976121,0.956490275,DB0930310050256_,0.044484657,-0.037052815,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1505798,DB09570,10022000,70,3831,68,3867,0.863771958,1.0390915,0.731164287,1.477362827,0.937256719,DB0957010022000_,0.064798055,0.038346774,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ixazomib,DB09570
,1506214,DB00210,10000496,99,786,30,319,0.214858551,1.339033386,0.861852043,2.131664301,0.367248892,DB0021010000496_,1.001715482,0.291948,NA,10000496,Acne,10040785,Skin and subcutaneous tissue disorders,Skin,adapalene,DB00210
,1506927,DB00704,10001639,394,3962,469,4725,1,1.001868346,0.86818487,1.155678835,1,DB0070410001639_,0,0.001866603,NA,10001639,Alcoholism,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,1507154,DB09331,10002034,41,2044,34,2395,0.160850077,1.41283798,0.871136405,2.304860756,0.298646909,DB0933110002034_,1.208493311,0.345600433,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,daratumumab,DB09331
,1507160,DB09331,10029366,34,2051,33,2396,0.461491979,1.203558015,0.72044741,2.01274876,0.628741858,DB0933110029366_,0.464034507,0.185282182,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,daratumumab,DB09331
,1507923,DB09045,10076573,52,2297,11,1713,2.97653073528897e-05,3.524428354,1.809949215,7.514025997,0.000281888,DB0904510076573_,8.173999502,1.259718254,female,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,dulaglutide,DB09045
,1508188,DB09331,10061623,36,2049,25,2404,0.051850927,1.689270453,0.982701227,2.946591239,0.128528493,DB0933110061623_,2.051604667,0.524296751,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,daratumumab,DB09331
,1508287,DB09570,10028810,88,3813,61,3874,0.025277034,1.465622761,1.04196112,2.072986424,0.074107058,DB0957010028810_,2.602244503,0.382280245,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ixazomib,DB09570
,1508480,DB00813,10077361,18,10554,42,10126,0.001132403,0.411196752,0.222651977,0.730567881,0.006101303,DB0081310077361_,5.099252855,-0.888683464,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,fentanyl,DB00813
,1508818,DB00722,10077692,44,25359,40,25992,0.587362145,1.127454436,0.71764851,1.775980117,0.73446144,DB0072210077692_,0.308617783,0.11996238,NA,10077692,Liver function test increased,10022891,Investigations,Inv,lisinopril,DB00722
,1509824,DB00295,10077361,25,14638,38,9564,0.001094645,0.429859075,0.24851915,0.731430164,0.00593191,DB0029510077361_,5.12740898,-0.844297856,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,morphine,DB00295
,1509958,DB09564,10020993,80,1147,89,858,0.015207083,0.672531165,0.484358207,0.932565438,0.049849496,DB0956410020993_,2.998746899,-0.396706826,NA,10020993,Hypoglycaemia,10027433,Metabolism and nutrition disorders,Metab,insulin degludec,DB09564
,1510634,DB06791,10047700,41,738,16,522,0.053200349,1.811726789,0.982338243,3.497651247,0.13103792,DB0679110047700_,2.03226853,0.594280418,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,lanreotide,DB06791
,1512242,DB11362,10003549,436,6047,151,2018,0.693457775,0.963588806,0.793286703,1.175398329,0.815403848,DB1136210003549_,0.204071769,-0.037090625,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1512254,DB11362,10020919,207,6276,67,2102,0.88735185,1.034790985,0.778302627,1.390492482,0.953324525,DB1136210020919_,0.047799903,0.034199459,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,selexipag,DB11362
,1513207,DB01024,10065154,34,2177,24,2096,0.290310369,1.363855219,0.78232841,2.412730808,0.455543434,DB0102410065154_,0.786264213,0.310315409,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,mycophenolic acid,DB01024
,1515087,DB08932,10005851,57,19386,12,6585,0.16465473,1.613383876,0.855315181,3.30592843,0.303648101,DB0893210005851_,1.19188581,0.47833376,NA,10005851,Blood urea increased,10022891,Investigations,Inv,macitentan,DB08932
,1516649,DB00343,10077361,38,8698,23,5072,0.894710408,0.96345249,0.558681757,1.695956564,0.955976233,DB0034310077361_,0.045022227,-0.037232102,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,1516652,DB00451,10077361,39,47232,30,15389,0.000641615,0.423566766,0.256363505,0.70629037,0.003810838,DB0045110077361_,5.569906188,-0.859044125,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,1516655,DB00722,10077361,18,25385,47,25985,0.000445301,0.3920104,0.21425529,0.688087979,0.002805208,DB0072210077361_,5.87627746,-0.93646691,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,1517882,DB00864,10077512,43,6826,39,8353,0.183006699,1.349173822,0.853096004,2.139718776,0.32766807,DB0086410077512_,1.115754166,0.299492422,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,tacrolimus,DB00864
,1520082,DB11362,10003988,361,6122,86,2083,0.003510375,1.428145233,1.119625165,1.838431844,0.015354057,DB1136210003988_,4.17637551,0.356376563,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1520085,DB11362,10013971,387,6096,121,2048,0.526906371,1.074500919,0.86821868,1.337245906,0.684647484,DB1136210013971_,0.378851195,0.071856292,NA,10013971,Dyspnoea exertional,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1520091,DB11362,10022004,120,6363,32,2137,0.298667351,1.259386847,0.843701572,1.928991575,0.46468991,DB1136210022004_,0.766384957,0.230624973,NA,10022004,Influenza like illness,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1520094,DB11362,10028391,151,6332,42,2127,0.313766171,1.207654756,0.849531625,1.749458461,0.481245445,DB1136210028391_,0.731377859,0.188680261,NA,10028391,Musculoskeletal pain,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1520100,DB11362,10028836,170,6313,43,2126,0.109061172,1.331335842,0.944070363,1.91348326,0.224616879,DB1136210028836_,1.493359088,0.28618283,NA,10028836,Neck pain,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1520656,DB00820,10069326,35,11880,19,5797,0.771747824,0.898888601,0.499760712,1.664929253,0.875084,DB0082010069326_,0.133435398,-0.106596166,NA,10069326,Product substitution issue,10077536,Product issues,Prod,tadalafil,DB00820
,1528665,DB00987,10077361,36,2068,60,2868,0.405223651,0.832141811,0.532499621,1.284146673,0.574919327,DB0098710077361_,0.553525549,-0.183752407,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,cytarabine,DB00987
,1533720,DB00196,10052015,33,5050,65,3220,5.8806299531568e-08,0.323760967,0.205722776,0.500864302,1.11765985769144e-06,DB0019610052015_,13.70427347,-1.127749793,male,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,fluconazole,DB00196
,1533726,DB01015,10052015,19,9868,56,9325,6.94662321092662e-06,0.320626349,0.179765157,0.548413565,7.89416303930852e-05,DB0101510052015_,9.446801834,-1.137478856,male,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,sulfamethoxazole,DB01015
,1533727,DB01137,10052015,18,7754,63,5530,7.27167185749886e-11,0.203788668,0.113426288,0.349023094,2.43330228866146e-09,DB0113710052015_,19.83401654,-1.590671761,male,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,levofloxacin,DB01137
,1536054,DB06218,10067482,36,1658,30,1406,1,1.017607492,0.605917734,1.720200647,1,DB0621810067482_,0,0.017454276,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,lacosamide,DB06218
,1536360,DB09303,10074425,158,26073,113,18846,0.950843858,1.010664197,0.7882332,1.299341417,0.989074787,DB0930310074425_,0.010985331,0.010607736,NA,10074425,Device defective,10077536,Product issues,Prod,evolocumab,DB09303
,1540206,DB01104,10070608,35,15428,18,7268,0.769177563,0.91601752,0.504531761,1.719316818,0.873604643,DB0110410070608_,0.13512736,-0.087719788,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,sertraline,DB01104
,1545124,DB06605,10076308,146,13927,138,12895,0.904991729,0.979571607,0.769869766,1.246984404,0.957667115,DB0660510076308_,0.043255041,-0.020639939,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,1547913,DB09303,10018484,98,26133,78,18881,0.54086049,0.907754849,0.66692928,1.239087929,0.696324932,DB0930310018484_,0.361938871,-0.096780927,NA,10018484,Glycosylated haemoglobin increased,10022891,Investigations,Inv,evolocumab,DB09303
,1552341,DB12159,10019211,73,3000,32,2036,0.044031477,1.548081508,1.004318297,2.434173909,0.113645656,DB1215910019211_,2.174669952,0.437016427,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,dupilumab,DB12159
,1552958,DB00563,10016062,31,46615,25,15323,0.001576719,0.407611065,0.232863845,0.720315647,0.008005422,DB0056310016062_,4.827636172,-0.897441832,NA,10016062,Facial paralysis,10029205,Nervous system disorders,Nerv,methotrexate,DB00563
,1554848,DB09331,10019211,32,2053,24,2405,0.106423469,1.561769542,0.888217193,2.780712867,0.220750886,DB0933110019211_,1.510720426,0.4458195,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,daratumumab,DB09331
,1554849,DB09331,10028334,33,2052,38,2391,1,1.011887198,0.61257059,1.66382838,1,DB0933110028334_,0,0.0118171,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,daratumumab,DB09331
,1554891,DB09076,10028813,50,758,23,587,0.051495477,1.682898177,0.994648047,2.925073388,0.127820824,DB0907610028813_,2.057125808,0.520517413,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,umeclidinium,DB09076
,1555393,DB00773,10077361,38,2285,40,2787,0.566953455,1.158673442,0.72066253,1.860139043,0.718212957,DB0077310077361_,0.330989157,0.147275767,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,etoposide,DB00773
,1556334,DB09570,10000059,42,3859,32,3903,0.244088471,1.32741264,0.81627581,2.177486157,0.402601999,DB0957010000059_,0.909806801,0.283231664,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,ixazomib,DB09570
,1556976,DB08932,10027141,31,19412,20,6577,0.034440712,0.525199421,0.28974278,0.972901458,0.094289565,DB0893210027141_,2.36138475,-0.64397724,NA,10027141,Melaena,10017947,Gastrointestinal disorders,Gastr,macitentan,DB08932
,1558992,DB09570,10027175,35,3866,16,3919,0.007364346,2.217283244,1.192992674,4.29787388,0.027878135,DB0957010027175_,3.579912603,0.796282683,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,ixazomib,DB09570
,1562136,DB09570,10013968,67,3834,73,3862,0.670378998,0.924544479,0.651464814,1.310290712,0.800059568,DB0957010013968_,0.223069094,-0.078454118,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ixazomib,DB09570
,1563843,DB09331,10018884,42,2043,20,2409,0.000738013,2.475737314,1.416174661,4.466394205,0.004274248,DB0933110018884_,5.45514713,0.906538256,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,daratumumab,DB09331
,1563846,DB09331,10029354,100,1985,82,2347,0.018431686,1.44177949,1.059009169,1.967479222,0.0579206,DB0933110029354_,2.848682178,0.365878108,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,daratumumab,DB09331
,1565037,DB09292,10048865,32,4497,108,8154,0.001764646,0.537270873,0.349678531,0.805149565,0.008769847,DB0929210048865_,4.736435936,-0.621252892,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,sacubitril,DB09292
,1565733,DB09564,10005557,104,1123,81,866,1,0.990119944,0.723068511,1.359512113,1,DB0956410005557_,0,-0.009929188,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,insulin degludec,DB09564
,1565865,DB11362,10052904,34,6449,17,2152,0.19391187,0.667424721,0.361809053,1.276626229,0.341608759,DB1136210052904_,1.074089176,-0.404328673,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1566584,DB01024,10054112,66,2145,70,2050,0.601229927,0.901121,0.63023827,1.287202704,0.745475194,DB0102410054112_,0.29373342,-0.104115735,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,mycophenolic acid,DB01024
,1567177,DB11362,10003239,611,5872,211,1958,0.672469519,0.965575954,0.817306817,1.144046657,0.801129885,DB1136210003239_,0.221732191,-0.035030512,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1567179,DB11362,10022437,273,6210,87,2082,0.709858416,1.052016786,0.819076484,1.362166407,0.82699355,DB1136210022437_,0.189958383,0.050709071,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,selexipag,DB11362
,1568998,DB06273,10077692,91,5004,35,1375,0.101199181,0.714469118,0.476451049,1.092633091,0.212623034,DB0627310077692_,1.548234474,-0.336215504,NA,10077692,Liver function test increased,10022891,Investigations,Inv,tocilizumab,DB06273
,1577914,DB00921,10022093,36,5809,32,4871,0.808521868,0.943375022,0.568611656,1.571528892,0.896651997,DB0092110022093_,0.109087456,-0.058291385,NA,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,1582277,DB09292,10050528,72,4457,124,8138,0.706976488,1.060189731,0.779847316,1.4323301,0.824750993,DB0929210050528_,0.192673765,0.058447883,NA,10050528,Ejection fraction decreased,10022891,Investigations,Inv,sacubitril,DB09292
,1582587,DB00047,10077512,32,9253,31,8487,0.899649261,0.946782609,0.558902006,1.605815802,0.956571579,DB0004710077512_,0.044399659,-0.05468577,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,insulin glargine,DB00047
,1584753,DB11581,10029354,72,1681,103,2657,0.527723366,1.104863604,0.800839963,1.517617781,0.685234831,DB1158110029354_,0.377993681,0.099721892,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,venetoclax,DB11581
,1584761,DB11581,10043554,35,1718,62,2698,0.600121657,0.886534695,0.565794815,1.369713875,0.744645491,DB1158110043554_,0.294847025,-0.120435017,NA,10043554,Thrombocytopenia,10005329,Blood and lymphatic system disorders,Blood,venetoclax,DB11581
,1585498,DB06605,10053483,43,14030,13,13020,0.000149717,3.06922802,1.619219844,6.224469431,0.001124537,DB0660510053483_,6.79038404,1.121426071,female,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,1585604,DB09331,10025482,49,2036,28,2401,0.002511963,2.063418548,1.266127001,3.42299677,0.011703793,DB0933110025482_,4.447842268,0.724364097,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,daratumumab,DB09331
,1585711,DB13879,10028813,370,2215,273,2545,1.71912906148096e-07,1.557081711,1.314195273,1.846542598,2.96504641607789e-06,DB1387910028813_,12.72861787,0.442813371,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,glecaprevir,DB13879
,1587168,DB09303,10048561,38,26193,32,18927,0.545821969,0.858090399,0.521832687,1.419349365,0.700533713,DB0930310048561_,0.355912787,-0.153045825,NA,10048561,Stent placement,10042613,Surgical and medical procedures,Surg,evolocumab,DB09303
,1587880,DB00051,10012434,48,25683,13,11407,0.126722238,1.639903701,0.874093718,3.30048123,0.251066107,DB0005110012434_,1.382039001,0.494637521,NA,10012434,Dermatitis allergic,10040785,Skin and subcutaneous tissue disorders,Skin,adalimumab,DB00051
,1589107,DB01611,10067482,43,11870,9,2352,0.851898771,0.946694714,0.454410648,2.211792062,0.927294854,DB0161110067482_,0.075483691,-0.05477861,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,1591478,DB04951,10054112,33,1849,51,3006,0.821553444,1.051928285,0.654980771,1.668908523,0.904937865,DB0495110054112_,0.099888995,0.050624942,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,pirfenidone,DB04951
,1592993,DB09292,10017577,64,4465,100,8162,0.325475727,1.169892652,0.839287494,1.620783645,0.493916603,DB0929210017577_,0.705388595,0.156911994,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,sacubitril,DB09292
,1594095,DB09331,10017413,31,2054,31,2398,0.608410027,1.167435764,0.68375839,1.993210607,0.751034851,DB0933110017413_,0.286303222,0.154809689,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,daratumumab,DB09331
,1598441,DB00904,10073085,46,23023,11,14445,0.002486435,2.623671833,1.338130367,5.618218886,0.011616204,DB0090410073085_,4.455354289,0.964574799,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,1600492,DB09303,10069803,263,25968,117,18842,8.39093395456607e-06,1.630995564,1.305731348,2.047394276,9.32385115179747e-05,DB0930310069803_,9.280349708,0.489190604,NA,10069803,Injury associated with device,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1601911,DB13867,10037162,46,4504,7,2547,0.000274807,3.715596058,1.662932302,9.770920962,0.001879109,DB1386710037162_,6.276957748,1.312539112,female,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,fluticasone,DB13867
,1602461,DB05676,10042609,44,47085,19,25310,0.508979423,1.244776543,0.711628431,2.258146809,0.669445027,DB0567610042609_,0.401306228,0.21895603,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,apremilast,DB05676
,1607321,DB09343,10029354,20,1499,34,1849,0.272735809,0.725649758,0.394018265,1.303533486,0.435638111,DB0934310029354_,0.830943401,-0.320687807,NA,10029354,Neutropenia,10005329,Blood and lymphatic system disorders,Blood,tipiracil,DB09343
,1607522,DB00904,10003664,55,23014,56,14400,0.010989764,0.614563627,0.415535942,0.908521369,0.038390053,DB0090410003664_,3.259956888,-0.486842813,NA,10003664,Atrial septal defect,10010331,"Congenital, familial and genetic disorders",Cong,ondansetron,DB00904
,1609143,DB11362,10006451,125,6358,19,2150,0.000627158,2.224649373,1.362451454,3.828371222,0.003737635,DB1136210006451_,5.589302171,0.799599318,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,selexipag,DB11362
,1609147,DB11362,10033557,234,6249,34,2135,6.16170200996345e-07,2.351256773,1.629646508,3.488371938,9.32145826370585e-06,DB1136210033557_,11.58319148,0.854949982,NA,10033557,Palpitations,10007541,Cardiac disorders,Card,selexipag,DB11362
,1609148,DB11362,10042772,244,6239,86,2083,0.697608717,0.947254296,0.733982745,1.232057052,0.81818943,DB1136210042772_,0.200661392,-0.054187694,NA,10042772,Syncope,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1611420,DB11595,10029366,45,1068,12,1022,2.28370505409179e-05,3.58627297,1.852844332,7.493786609,0.000223732,DB1159510029366_,8.405063454,1.277113493,female,10029366,Neutrophil count decreased,10022891,Investigations,Inv,atezolizumab,DB11595
,1611662,DB00887,10054112,63,2278,44,1771,0.622432772,1.113084494,0.741433676,1.683991528,0.76261147,DB0088710054112_,0.271006592,0.107134985,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,bumetanide,DB00887
,1612530,DB00321,10037162,44,7403,9,2841,0.090572838,1.876105118,0.902373278,4.376706796,0.196152842,DB0032110037162_,1.628861117,0.629197882,NA,10037162,Psoriatic arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,amitriptyline,DB00321
,1612832,DB08904,10022067,47,11563,13,3546,0.878797809,1.108714069,0.589319616,2.236313361,0.949052042,DB0890410022067_,0.052291643,0.103200847,NA,10022067,Injection site haemorrhage,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,1617538,DB09303,10038428,33,26198,20,18939,0.579531636,1.192796156,0.664243073,2.194336554,0.728206566,DB0930310038428_,0.317170527,0.176300262,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,evolocumab,DB09303
,1618056,DB06605,10040844,37,14036,16,13017,0.008934487,2.144468952,1.163356015,4.131296071,0.032522225,DB0660510040844_,3.425831589,0.762891947,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,apixaban,DB06605
,1624991,DB08932,10077692,65,19378,16,6581,0.305631761,1.379634295,0.788505054,2.556741111,0.4724078,DB0893210077692_,0.749912683,0.32181846,NA,10077692,Liver function test increased,10022891,Investigations,Inv,macitentan,DB08932
,1625300,DB09331,10035528,61,2024,62,2367,0.463983421,1.150566439,0.790369958,1.674429961,0.631220134,DB0933110035528_,0.460100611,0.140254376,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,daratumumab,DB09331
,1625563,DB09570,10061623,80,3821,67,3868,0.279232674,1.208685757,0.859875691,1.703474941,0.443094017,DB0957010061623_,0.813973304,0.189533618,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,1626341,DB09303,10042609,64,26167,32,18927,0.097492515,1.446618359,0.931862876,2.286720791,0.207104579,DB0930310042609_,1.574531402,0.369228666,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,evolocumab,DB09303
,1628166,DB09570,10047513,40,3861,25,3910,0.061948412,1.620196964,0.957002863,2.792449332,0.147059291,DB0957010047513_,1.916919432,0.482547724,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,ixazomib,DB09570
,1628870,DB00222,10010144,28,3178,37,3091,0.261782621,0.736078577,0.43276808,1.239223478,0.423469221,DB0022210010144_,0.859274446,-0.306418404,NA,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,glimepiride,DB00222
,1628979,DB09570,10037087,45,3856,31,3904,0.107021517,1.469603331,0.90754722,2.407719316,0.221657914,DB0957010037087_,1.506620014,0.384992521,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ixazomib,DB09570
,1629071,DB11362,10062355,279,6204,73,2096,0.059478519,1.291166944,0.989464482,1.702704236,0.142528295,DB1136210062355_,1.948214734,0.255546418,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1633386,DB08932,10066400,56,19387,14,6583,0.338186277,1.358194422,0.745587585,2.643992345,0.507257274,DB0893210066400_,0.678736959,0.306156187,NA,10066400,Emergency care,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,1634103,DB00158,10076308,41,16774,32,8072,0.044952089,0.616566492,0.378597025,1.012337479,0.115477488,DB0015810076308_,2.158679674,-0.483589108,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,1634951,DB11581,10038695,16,1737,41,2719,0.101606166,0.610928377,0.318982126,1.116637856,0.213307621,DB1158110038695_,1.545019926,-0.492775549,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,venetoclax,DB11581
,1635157,DB01042,10043645,17,973,42,1286,0.032498141,0.535107225,0.283767984,0.967255545,0.090197311,DB0104210043645_,2.405755667,-0.625288131,NA,10043645,Thrombotic microangiopathy,10005329,Blood and lymphatic system disorders,Blood,melphalan,DB01042
,1636254,DB00381,10077692,66,29294,33,22854,0.042089504,1.560303942,1.012154238,2.447788893,0.109879586,DB0038110077692_,2.20837019,0.444880637,NA,10077692,Liver function test increased,10022891,Investigations,Inv,amlodipine,DB00381
,1637230,DB09035,10061818,33,4693,38,6652,0.399137751,1.230894872,0.746941993,2.018959581,0.569006171,DB0903510061818_,0.563863999,0.207741443,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,nivolumab,DB09035
,1638662,DB09107,10013700,528,687,377,626,0.005469222,1.276024781,1.071865816,1.519765932,0.021974701,DB0910710013700_,3.817863425,0.243749605,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,methoxy polyethylene glycol-epoetin beta,DB09107
,1638706,DB09331,10033371,29,2056,36,2393,0.90040672,0.937590038,0.552405703,1.578832,0.956698706,DB0933110033371_,0.044266769,-0.064442485,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,daratumumab,DB09331
,1639007,DB11362,10002855,147,6336,31,2138,0.017993114,1.59995653,1.076457237,2.447143377,0.056846265,DB1136210002855_,2.867404761,0.46997646,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,selexipag,DB11362
,1639008,DB11362,10010264,474,6009,145,2024,0.336247168,1.101065774,0.905779533,1.344668959,0.505303117,DB1136210010264_,0.682596798,0.096278597,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1639011,DB11362,10016334,55,6428,14,2155,0.404975273,1.31700673,0.720766815,2.570078045,0.574678781,DB1136210016334_,0.553944036,0.275361533,NA,10016334,Feeling hot,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1639014,DB11362,10020642,53,6430,14,2155,0.481762792,1.268730105,0.692261311,2.481219659,0.646292647,DB1136210020642_,0.436502863,0.238016483,NA,10020642,Hyperhidrosis,10040785,Skin and subcutaneous tissue disorders,Skin,selexipag,DB11362
,1639020,DB11362,10028735,234,6249,50,2119,0.002704704,1.586960207,1.159863556,2.208008138,0.012423442,DB1136210028735_,4.388170103,0.461820367,NA,10028735,Nasal congestion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1640046,DB11362,10008531,105,6378,36,2133,0.92197248,0.975425089,0.659901641,1.471592404,0.965538334,DB1136210008531_,0.035069474,-0.024881914,NA,10008531,Chills,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1640047,DB11362,10010774,182,6301,57,2112,0.705420588,1.070230838,0.787258476,1.473733831,0.823502406,DB1136210010774_,0.194188808,0.067874361,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1640053,DB11362,10033775,64,6419,22,2147,0.900782476,0.973022247,0.589577482,1.663336761,0.956764412,DB1136210033775_,0.044198092,-0.027348333,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1640591,DB00281,10053664,46,11412,11,5660,0.033321871,2.073975903,1.057196955,4.443709151,0.091973684,DB0028110053664_,2.386252789,0.729467491,NA,10053664,Infusion site pruritus,10018065,General disorders and administration site conditions,Genrl,lidocaine,DB00281
,1640896,DB11362,10056819,64,6419,10,2159,0.021355281,2.152572303,1.09529285,4.710959061,0.065123127,DB1136210056819_,2.731475542,0.766663547,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1640912,DB00497,10077361,34,19233,83,16292,6.42822687356937e-08,0.347008804,0.225548318,0.523397031,1.21339995240051e-06,DB0049710077361_,13.62208426,-1.058405128,male,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,1640924,DB11362,10013946,181,6302,45,2124,0.073639772,1.355563518,0.969260579,1.930623293,0.16757176,DB1136210013946_,1.786343604,0.304217249,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1642220,DB11362,10011906,757,5726,377,1792,3.21353202349725e-11,0.628444008,0.548405521,0.720961498,1.13608189963181e-09,DB1136210011906_,20.59568042,-0.464508344,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1642706,DB09570,10061818,21,3880,32,3903,0.167746884,0.660178171,0.361109518,1.183083935,0.307864222,DB0957010061818_,1.17809643,-0.415245525,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,1643122,DB11362,10033318,338,6145,103,2066,0.429802707,1.103271817,0.877071979,1.397256848,0.598297404,DB1136210033318_,0.513667318,0.098280145,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,selexipag,DB11362
,1643124,DB11362,10037884,39,6444,14,2155,0.873659455,0.931598596,0.493685018,1.86118309,0.945065179,DB1136210037884_,0.056501382,-0.070853248,NA,10037884,Rash pruritic,10040785,Skin and subcutaneous tissue disorders,Skin,selexipag,DB11362
,1643308,DB11362,10018884,188,6295,44,2125,0.031313607,1.442245353,1.029689252,2.058819028,0.087598783,DB1136210018884_,2.434988171,0.366201172,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,selexipag,DB11362
,1643408,DB09564,10012735,45,1182,44,903,0.275576278,0.781417924,0.499254693,1.22371928,0.438868371,DB0956410012735_,0.823555749,-0.246645159,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,insulin degludec,DB09564
,1643411,DB09564,10013968,44,1183,25,922,0.220144951,1.371502656,0.814242629,2.357069976,0.373648665,DB0956410013968_,0.984439322,0.315906968,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,insulin degludec,DB09564
,1643563,DB11595,10035742,36,1077,34,1000,1,0.983128179,0.592840041,1.633371479,1,DB1159510035742_,0,-0.017015772,NA,10035742,Pneumonitis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atezolizumab,DB11595
,1643958,DB11362,10025082,102,6381,36,2133,0.766999145,0.947110389,0.639647627,1.430882106,0.871902802,DB1136210025082_,0.137077327,-0.054339626,NA,10025082,Lung disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1644044,DB09303,10002034,34,26197,19,18940,0.405506126,1.29375204,0.717058744,2.401762897,0.575121595,DB0930310002034_,0.55317379,0.257546555,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,evolocumab,DB09303
,1644342,DB09303,10021097,62,26169,26,18933,0.022615361,1.72521896,1.074670948,2.843130508,0.067990936,DB0930310021097_,2.688380881,0.545353976,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,evolocumab,DB09303
,1644352,DB01611,10077692,90,11823,20,2341,0.607527362,0.890997513,0.542989188,1.530816759,0.750433831,DB0161110077692_,0.287103799,-0.115413642,NA,10077692,Liver function test increased,10022891,Investigations,Inv,hydroxychloroquine,DB01611
,1644441,DB09303,10038683,40,26191,38,18921,0.251056658,0.760459114,0.475267786,1.21863317,0.410962122,DB0930310038683_,0.889254231,-0.273832931,NA,10038683,Respiratory disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,evolocumab,DB09303
,1644531,DB09303,10077692,35,26196,22,18937,0.687658116,1.150028005,0.6557786,2.05855847,0.811687484,DB0930310077692_,0.208639884,0.139786295,NA,10077692,Liver function test increased,10022891,Investigations,Inv,evolocumab,DB09303
,1644554,DB09303,10003285,64,26167,40,18919,0.488029215,1.156783761,0.766965819,1.763575978,0.651642045,DB0930310003285_,0.428259879,0.145643534,NA,10003285,Arthropathy,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1645281,DB11595,10012735,45,1068,33,1001,0.30142629,1.277942205,0.790347766,2.085388359,0.467695171,DB1159510012735_,0.75993854,0.245251132,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,atezolizumab,DB11595
,1645998,DB00704,10012335,21,4335,33,5161,0.340500184,0.757640447,0.415909149,1.351405661,0.509702862,DB0070410012335_,0.673927346,-0.27754635,NA,10012335,Dependence,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,1646228,DB09570,10047942,86,3815,69,3866,0.167786471,1.262997957,0.906319291,1.765617849,0.307882815,DB0957010047942_,1.178036038,0.233488226,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,ixazomib,DB09570
,1646359,DB00704,10047899,56,4300,44,5150,0.043087095,1.524227285,1.006428701,2.32137909,0.111850704,DB0070410047899_,2.190590301,0.421487584,NA,10047899,Weight increased,10022891,Investigations,Inv,naltrexone,DB00704
,1646523,DB00193,10077692,39,19281,12,8690,0.290144952,1.464788897,0.750930008,3.074487435,0.455311049,DB0019310077692_,0.786774469,0.381711135,NA,10077692,Liver function test increased,10022891,Investigations,Inv,tramadol,DB00193
,1646527,DB00588,10077692,39,16485,13,8455,0.189813405,1.538646782,0.803459804,3.143262213,0.336281829,DB0058810077692_,1.089805695,0.430903317,NA,10077692,Liver function test increased,10022891,Investigations,Inv,fluticasone propionate,DB00588
,1646701,DB11362,10001053,65,6418,26,2143,0.465513063,0.834752623,0.520702312,1.374637475,0.632314471,DB1136210001053_,0.458368428,-0.180619858,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1646720,DB11362,10050584,64,6419,14,2155,0.188376367,1.534613154,0.849347701,2.969919014,0.33450247,DB1136210050584_,1.095111016,0.428278333,NA,10050584,Contusion,10022117,"Injury, poisoning and procedural complications",Inj&P,selexipag,DB11362
,1646731,DB11362,10069339,67,6416,31,2138,0.158651794,0.720235157,0.462447479,1.144275789,0.295703769,DB1136210069339_,1.218397106,-0.328177514,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,selexipag,DB11362
,1647294,DB00028,10075107,69,13389,16,5599,0.03162758,1.803348637,1.034683141,3.332114725,0.088279808,DB0002810075107_,2.427243874,0.58964529,NA,10075107,Administration site swelling,10018065,General disorders and administration site conditions,Genrl,human immunoglobulin g,DB00028
,1647298,DB00668,10075107,48,10043,10,4293,0.042967114,2.051730372,1.023760077,4.552912487,0.111610891,DB0066810075107_,2.192736647,0.718683521,NA,10075107,Administration site swelling,10018065,General disorders and administration site conditions,Genrl,epinephrine,DB00668
,1647300,DB01075,10075107,45,19903,9,11088,0.00264573,2.785425321,1.343955984,6.483081931,0.012200526,DB0107510075107_,4.406276173,1.02440058,female,10075107,Administration site swelling,10018065,General disorders and administration site conditions,Genrl,diphenhydramine,DB01075
,1647315,DB09570,10018884,32,3869,36,3899,0.715286885,0.895794217,0.537435445,1.48704535,0.8314016,DB0957010018884_,0.184642328,-0.110044561,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,ixazomib,DB09570
,1647474,DB00316,10075107,41,65433,9,36944,0.007494694,2.572072645,1.231209389,6.020523556,0.028278091,DB0031610075107_,3.565667955,0.94471205,NA,10075107,Administration site swelling,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,1647801,DB11362,10006002,85,6398,28,2141,1,1.015861058,0.65379062,1.622451635,1,DB1136210006002_,0,0.015736586,NA,10006002,Bone pain,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1647802,DB11362,10016322,363,6120,101,2068,0.09850068,1.214426888,0.965728004,1.53820541,0.208638155,DB1136210016322_,1.567153842,0.194272268,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1647859,DB09029,10065154,175,11169,116,7154,0.808658988,0.966285667,0.75833178,1.235110327,0.896785145,DB0902910065154_,0.108938972,-0.034295767,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,secukinumab,DB09029
,1648113,DB11362,10007554,142,6341,59,2110,0.161698701,0.800879306,0.584666742,1.108805781,0.299682732,DB1136210007554_,1.205030923,-0.222045022,NA,10007554,Cardiac failure,10007541,Cardiac disorders,Card,selexipag,DB11362
,1648114,DB11362,10037400,275,6208,108,2061,0.148213629,0.845391382,0.670316278,1.072225062,0.281526022,DB1136210037400_,1.267530397,-0.167955585,NA,10037400,Pulmonary hypertension,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1648286,DB06605,10024774,23,14050,31,13002,0.175594568,0.686608096,0.382090431,1.21706038,0.318098159,DB0660510024774_,1.145395268,-0.375991606,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,apixaban,DB06605
,1648505,DB09078,10010774,30,763,57,999,0.120212327,0.689243786,0.423130582,1.102980332,0.241656612,DB0907810010774_,1.420237521,-0.372160245,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,lenvatinib,DB09078
,1648524,DB09078,10013952,16,777,43,1013,0.015480093,0.485291646,0.253159936,0.887135386,0.050517631,DB0907810013952_,2.985432883,-0.723005237,NA,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenvatinib,DB09078
,1648587,DB09078,10031009,26,767,32,1024,0.788446705,1.084697166,0.615266391,1.896183226,0.885444006,DB0907810031009_,0.121666058,0.081300839,NA,10031009,Oral pain,10017947,Gastrointestinal disorders,Gastr,lenvatinib,DB09078
,1649011,DB11362,10000059,379,6104,117,2052,0.455341459,1.088959143,0.877200592,1.359796789,0.622831954,DB1136210000059_,0.473478533,0.085222325,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1649013,DB11362,10059168,107,6376,25,2144,0.106084117,1.439106581,0.921291214,2.328816906,0.220336642,DB1136210059168_,1.512598713,0.364022491,NA,10059168,Oxygen consumption increased,10022891,Investigations,Inv,selexipag,DB11362
,1649014,DB11362,10061822,157,6326,50,2119,0.807896682,1.051767091,0.757410462,1.482307093,0.896336842,DB1136210061822_,0.109438997,0.050471693,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1649351,DB08904,10067482,292,11318,148,3411,1.06109872400362e-06,0.594634951,0.484387161,0.732428387,1.50802811356773e-05,DB0890410067482_,11.10212255,-0.51980759,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,1649715,DB01238,10078070,59,5191,56,3446,0.068228012,0.699449444,0.475608182,1.029592926,0.158096998,DB0123810078070_,1.844546521,-0.357461761,NA,10078070,Gambling disorder,10037175,Psychiatric disorders,Psych,aripiprazole,DB01238
,1650650,DB11362,10025482,709,5774,187,1982,0.001970614,1.301383199,1.096977073,1.549582596,0.00961708,DB1136210025482_,4.644214635,0.263427698,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1650651,DB11362,10028334,258,6225,73,2096,0.219097931,1.189975645,0.909699883,1.572596092,0.372400603,DB1136210028334_,0.987785116,0.17393284,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1650663,DB11362,10020937,58,6425,27,2142,0.166148913,0.716190838,0.444990896,1.179531715,0.305625055,DB1136210020937_,1.185396237,-0.333808614,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1650933,DB11362,10040984,56,6427,15,2154,0.494145457,1.251181692,0.696205563,2.38717356,0.656739251,DB1136210040984_,0.420468218,0.224088458,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,selexipag,DB11362
,1650937,DB11362,10061428,492,5991,129,2040,0.010798192,1.29862666,1.060384069,1.599425256,0.037856683,DB1136210061428_,3.273947749,0.261307291,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,selexipag,DB11362
,1651042,DB09029,10068945,93,11251,98,7172,0.000583696,0.604969425,0.4497894,0.813096913,0.00351367,DB0902910068945_,5.651094335,-0.502577359,NA,10068945,Incorrect dose administered by device,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,1651100,DB09053,10054112,45,2240,74,3978,0.700415556,1.079920294,0.725706472,1.591515993,0.819917974,DB0905310054112_,0.198550975,0.076887236,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,ibrutinib,DB09053
,1651156,DB08932,10038647,54,19389,14,6583,0.405553523,1.309559005,0.716785825,2.554818233,0.575167383,DB0893210038647_,0.55309418,0.269690443,NA,10038647,Respiration abnormal,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,macitentan,DB08932
,1651785,DB00531,10077361,71,7181,68,6448,0.733119192,0.937570669,0.661524231,1.329614836,0.845157481,DB0053110077361_,0.168232301,-0.064463144,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,cyclophosphamide,DB00531
,1651841,DB11362,10005750,52,6431,17,2152,1,1.023577594,0.580876903,1.892287123,1,DB1136210005750_,0,0.023303936,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,selexipag,DB11362
,1652050,DB00108,10066901,53,10141,11,3284,0.19227195,1.560201662,0.804238783,3.316706451,0.339481978,DB0010810066901_,1.080334417,0.444815084,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,natalizumab,DB00108
,1652058,DB09570,10033371,62,3839,36,3899,0.008008524,1.749004704,1.13871208,2.722563795,0.029805883,DB0957010033371_,3.513049503,0.559046885,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,1652144,DB09303,10037876,51,26180,25,18934,0.130079044,1.475362806,0.897043967,2.485868034,0.255817416,DB0930310037876_,1.363291306,0.38890393,NA,10037876,Rash papular,10040785,Skin and subcutaneous tissue disorders,Skin,evolocumab,DB09303
,1652334,DB08880,10061822,42,3296,9,800,0.859673986,1.132652768,0.540604479,2.657490388,0.933663777,DB0888010061822_,0.068638888,0.124562463,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,teriflunomide,DB08880
,1652376,DB06273,10061822,69,5026,10,1400,0.053891587,1.921788062,0.981333682,4.195983016,0.132300399,DB0627310061822_,2.022680192,0.653256035,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,1652415,DB00381,10077512,49,29311,81,22806,2.65616577901831e-05,0.470686471,0.323053803,0.679645421,0.000254483,DB0038110077512_,8.276277862,-0.753563073,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,amlodipine,DB00381
,1652419,DB00695,10077512,64,27985,74,20454,0.007405992,0.63214153,0.4449613,0.895918575,0.028009568,DB0069510077512_,3.575209105,-0.458641969,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,furosemide,DB00695
,1652421,DB01076,10077512,37,25710,67,25516,0.003110002,0.548081528,0.356445218,0.83114319,0.01393444,DB0107610077512_,4.27339182,-0.601331229,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,atorvastatin,DB01076
,1652423,DB01275,10077512,28,3951,38,3311,0.062064253,0.617533858,0.364168585,1.035572144,0.147307679,DB0127510077512_,1.915231826,-0.482021382,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,hydralazine,DB01275
,1652470,DB11362,10008479,399,6084,97,2072,0.003299611,1.400783809,1.112746144,1.777440597,0.014612126,DB1136210008479_,4.22590356,0.337031943,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1653621,DB09035,10076309,101,4625,107,6583,0.039167944,1.343482844,1.010626275,1.784969607,0.103961367,DB0903510076309_,2.26373592,0.295265379,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,nivolumab,DB09035
,1654787,DB09570,10011224,35,3866,36,3899,1,0.980520725,0.596446097,1.610368612,1,DB0957010011224_,0,-0.019671497,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ixazomib,DB09570
,1654853,DB11574,10013573,20,890,46,1027,0.011522464,0.5018765,0.278975353,0.873198728,0.039878543,DB1157410013573_,3.22191686,-0.689401205,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,elbasvir,DB11574
,1654854,DB11574,10016256,269,641,319,754,0.960661483,0.991919465,0.81342964,1.209138905,0.998240283,DB1157410016256_,0.001761267,-0.008113359,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,elbasvir,DB11574
,1654904,DB11362,10000081,166,6317,33,2136,0.004759933,1.700911679,1.160798532,2.560559637,0.019662871,DB1136210000081_,3.929023151,0.531164389,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1655580,DB11362,10062237,39,6444,15,2154,0.637884174,0.869121279,0.467300451,1.700661019,0.775127618,DB1136210062237_,0.254727595,-0.140272601,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,selexipag,DB11362
,1656083,DB09343,10054112,32,1487,38,1845,0.903541694,1.044855267,0.628571483,1.726838524,0.957409002,DB0934310054112_,0.043524599,0.043878375,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,tipiracil,DB09343
,1656365,DB00996,10077361,47,38906,20,22405,0.309879233,1.353300182,0.786197388,2.411751633,0.477323796,DB0099610077361_,0.7395602,0.302546189,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,1656367,DB01076,10077361,27,25720,34,25549,0.37248529,0.788843484,0.457635962,1.347393543,0.542199964,DB0107610077361_,0.612120408,-0.23718735,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,1656368,DB01104,10077361,39,15424,24,7262,0.343639879,0.76507011,0.448287979,1.331090118,0.512893885,DB0110410077361_,0.667686306,-0.267787803,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,sertraline,DB01104
,1656550,DB09045,10022081,30,2319,27,1697,0.500058861,0.813136772,0.465272548,1.427360501,0.661718316,DB0904510022081_,0.412915318,-0.206855952,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,dulaglutide,DB09045
,1656860,DB08907,10043913,53,4200,139,3771,4.16355288912763e-12,0.342390806,0.243893345,0.47465143,1.69936316289938e-10,DB0890710043913_,22.49559736,-1.071802488,male,10043913,Toe amputation,10042613,Surgical and medical procedures,Surg,canagliflozin,DB08907
,1656888,DB09570,10033775,72,3829,31,3904,3.91432525208958e-05,2.367917832,1.529985925,3.742858634,0.000358198,DB0957010033775_,7.934423959,0.862011017,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,ixazomib,DB09570
,1657333,DB11362,10002034,234,6249,51,2118,0.004280389,1.554967812,1.139354378,2.157557708,0.018047805,DB1136210002034_,4.014731186,0.441454846,NA,10002034,Anaemia,10005329,Blood and lymphatic system disorders,Blood,selexipag,DB11362
,1658436,DB00264,10077512,55,29552,76,24816,0.004875184,0.607719919,0.421382563,0.871573387,0.020050731,DB0026410077512_,3.909489681,-0.498041163,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,metoprolol,DB00264
,1658437,DB00316,10077512,67,65407,77,36876,2.54162138434189e-05,0.490565522,0.34810227,0.689840203,0.000245027,DB0031610077512_,8.314143548,-0.712196427,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,acetaminophen,DB00316
,1658439,DB00927,10077512,33,7464,45,4971,0.001693707,0.488418666,0.301506235,0.783837935,0.008479826,DB0092710077512_,4.770065367,-0.716582318,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,famotidine,DB00927
,1660586,DB00451,10077512,45,47226,24,15395,0.067531361,0.611228864,0.364435954,1.049290497,0.156912888,DB0045110077512_,1.852064484,-0.492283817,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,levothyroxine,DB00451
,1663497,DB01202,10077361,30,6684,30,5688,0.603945399,0.851000238,0.49498008,1.463075375,0.747431839,DB0120210077361_,0.291112163,-0.161342871,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,1664516,DB09292,10061428,41,4488,70,8192,0.765146194,1.069104681,0.707532021,1.597102479,0.870436377,DB0929210061428_,0.138760611,0.066821552,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,sacubitril,DB09292
,1665254,DB09303,10029331,57,26174,36,18923,0.599213451,1.14466487,0.740910689,1.789611295,0.743904856,DB0930310029331_,0.295842134,0.135111904,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,evolocumab,DB09303
,1665413,DB09303,10013538,37,26194,18,18941,0.174314266,1.486367364,0.824765053,2.774274463,0.31653544,DB0930310013538_,1.150320069,0.396335133,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,evolocumab,DB09303
,1666209,DB01183,10021097,31,528,22,526,0.261236309,1.403320052,0.775221418,2.580061717,0.422799304,DB0118310021097_,0.860857671,0.338840895,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,naloxone,DB01183
,1666259,DB14185,10002855,38,526,36,597,0.472466596,1.197851041,0.72725313,1.976213148,0.638481504,DB1418510002855_,0.448662572,0.180529152,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,aripiprazole lauroxil,DB14185
,1666260,DB14185,10012378,23,541,32,601,0.489830506,0.798613605,0.440320961,1.42785625,0.6531689,DB1418510012378_,0.425919531,-0.224878048,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,aripiprazole lauroxil,DB14185
,1666262,DB14185,10053762,97,467,78,555,0.017637911,1.47742191,1.057208205,2.069626471,0.056008757,DB1418510053762_,2.882247222,0.390298616,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole lauroxil,DB14185
,1666356,DB11362,10003246,52,6431,11,2158,0.189678298,1.586162411,0.815791596,3.377491935,0.336099101,DB1136210003246_,1.090349218,0.461317521,NA,10003246,Arthritis,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1666357,DB11362,10019303,164,6319,43,2126,0.167453507,1.283138673,0.908597722,1.846491095,0.307465016,DB1136210019303_,1.179393968,0.249309165,NA,10019303,Heart rate increased,10022891,Investigations,Inv,selexipag,DB11362
,1666363,DB11362,10024264,48,6435,33,2136,0.001829833,0.482846207,0.302741785,0.778675348,0.009046144,DB1136210024264_,4.705416678,-0.728057088,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1667066,DB08895,10064848,36,28078,14,6632,0.146978899,0.607380913,0.319462523,1.219787243,0.279749483,DB0889510064848_,1.273860779,-0.498599152,NA,10064848,Chronic kidney disease,10038359,Renal and urinary disorders,Renal,tofacitinib,DB08895
,1667465,DB11362,10016173,328,6155,101,2068,0.492970041,1.091114342,0.865256317,1.38545308,0.655837911,DB1136210016173_,0.421841608,0.087199506,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,selexipag,DB11362
,1667466,DB11362,10024855,152,6331,54,2115,0.684820803,0.940348129,0.682171029,1.313047623,0.809622937,DB1136210024855_,0.21118665,-0.061505122,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1667469,DB11362,10028372,87,6396,21,2148,0.218428147,1.391240611,0.85364077,2.365845862,0.37166842,DB1136210028372_,0.989753166,0.330195875,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1668273,DB11362,10035598,94,6389,34,2135,0.681855767,0.923877401,0.615945839,1.41542516,0.807559819,DB1136210035598_,0.213738148,-0.079175899,NA,10035598,Pleural effusion,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1668756,DB09570,10005724,35,3866,16,3919,0.007364346,2.217283244,1.192992674,4.29787388,0.027878135,DB0957010005724_,3.579912603,0.796282683,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,ixazomib,DB09570
,1669605,DB06605,10037437,38,14035,36,12997,1,0.977485104,0.60270603,1.587976408,1,DB0660510037437_,0,-0.022772227,NA,10037437,Pulmonary thrombosis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,apixaban,DB06605
,1669698,DB01281,10065154,189,8743,28,1770,0.141372434,1.366482349,0.9121195,2.118704227,0.271774623,DB0128110065154_,1.302782149,0.312239809,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,abatacept,DB01281
,1669967,DB06791,10013573,40,739,18,520,0.133764244,1.563166909,0.864421129,2.931064742,0.260994926,DB0679110013573_,1.343254312,0.446713833,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,lanreotide,DB06791
,1670857,DB11362,10008190,45,6438,21,2148,0.201645951,0.714981536,0.416057418,1.26663335,0.351056422,DB1136210008190_,1.046808322,-0.335498561,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1671461,DB09564,10037844,67,1160,32,915,0.022344917,1.651166431,1.057738742,2.625057998,0.06740144,DB0956410037844_,2.697088896,0.501481966,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,insulin degludec,DB09564
,1672019,DB09303,10061822,39,26192,29,18930,0.902828605,0.971948845,0.585544915,1.630369191,0.957326661,DB0930310061822_,0.043610607,-0.028452105,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1672455,DB00695,10077107,45,28004,19,20509,0.043121085,1.734510905,0.993826949,3.14123253,0.111911307,DB0069510077107_,2.190048624,0.550725474,NA,10077107,Complication associated with device,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,1673365,DB11362,10012174,170,6313,43,2126,0.109061172,1.331335842,0.944070363,1.91348326,0.224616879,DB1136210012174_,1.493359088,0.28618283,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,selexipag,DB11362
,1673367,DB11362,10037087,122,6361,23,2146,0.008898741,1.789503101,1.135775246,2.936701631,0.032421633,DB1136210037087_,3.428929379,0.581937984,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,selexipag,DB11362
,1673368,DB11362,10047895,323,6160,93,2076,0.202285122,1.170460111,0.921319692,1.4985791,0.35168096,DB1136210047895_,1.045030879,0.157396928,NA,10047895,Weight decreased,10022891,Investigations,Inv,selexipag,DB11362
,1674443,DB00541,10077361,48,3086,63,4234,0.846706191,1.045359302,0.700617903,1.550933803,0.922998542,DB0054110077361_,0.080127624,0.044360656,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,vincristine,DB00541
,1674444,DB00563,10077361,80,46566,60,15288,2.89145707542957e-06,0.437746738,0.30915396,0.622736649,3.67247882230811e-05,DB0056310077361_,10.2120586,-0.826114759,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,1675579,DB00704,10022044,49,4307,25,5169,0.000391107,2.352078459,1.422159095,3.981375762,0.002516891,DB0070410022044_,5.984730881,0.855299388,NA,10022044,Injection site abscess,10021881,Infections and infestations,Infec,naltrexone,DB00704
,1676049,DB11362,10036790,126,6357,44,2125,0.789081593,0.957250257,0.671558204,1.38682407,0.885694655,DB1136210036790_,0.121383021,-0.04369042,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1676051,DB11362,10039163,133,6350,47,2122,0.728719194,0.945640935,0.670658981,1.353599802,0.841846954,DB1136210039163_,0.172157046,-0.055892343,NA,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,selexipag,DB11362
,1676435,DB06605,10069868,40,14033,12,13021,0.00025238,3.092599788,1.589866985,6.478852224,0.001749886,DB0660510069868_,6.348204455,1.129012093,female,10069868,Device issue,10077536,Product issues,Prod,apixaban,DB06605
,1677431,DB00795,10061822,181,4388,24,1479,3.22874317185503e-06,2.541477475,1.647065029,4.086535992,4.03842561371447e-05,DB0079510061822_,10.11707055,0.932745595,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,sulfasalazine,DB00795
,1677968,DB11362,10061818,161,6322,46,2123,0.372256901,1.175314578,0.83874845,1.674990265,0.541897523,DB1136210061818_,0.612678367,0.161535837,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1677970,DB09029,10076309,54,11290,26,7244,0.251832194,1.332595289,0.81927084,2.219052822,0.411910373,DB0902910076309_,0.886949495,0.287128386,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,1678397,DB11581,10011906,479,1274,768,1992,0.732758744,0.975202852,0.850670101,1.117389679,0.844835669,DB1158110011906_,0.168613145,-0.025109776,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,venetoclax,DB11581
,1678841,DB09303,10061024,57,26174,50,18909,0.327778628,0.823583462,0.553124418,1.229641096,0.496279556,DB0930310061024_,0.700615891,-0.194090385,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,evolocumab,DB09303
,1679674,DB11362,10017955,85,6398,28,2141,1,1.015861058,0.65379062,1.622451635,1,DB1136210017955_,0,0.015736586,NA,10017955,Gastrointestinal haemorrhage,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1679676,DB11362,10018838,45,6438,15,2154,1,1.00372766,0.547837136,1.942660931,1,DB1136210018838_,0,0.003720729,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,selexipag,DB11362
,1679677,DB11362,10066152,154,6329,39,2130,0.130281809,1.328864455,0.926342476,1.947086803,0.256129945,DB1136210066152_,1.362070367,0.284324785,NA,10066152,Transfusion,10042613,Surgical and medical procedures,Surg,selexipag,DB11362
,1680318,DB09303,10012601,70,26161,66,18893,0.138769944,0.765963147,0.539038266,1.089462257,0.268055704,DB0930310012601_,1.31656047,-0.266621221,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,evolocumab,DB09303
,1681674,DB00997,10077361,29,5302,32,3482,0.048502129,0.595219637,0.346717507,1.017840119,0.12226062,DB0099710077361_,2.101600281,-0.518824804,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,doxorubicin,DB00997
,1682373,DB09029,10013538,35,11309,21,7249,0.891263069,1.068328285,0.60425822,1.933026435,0.954816394,DB0902910013538_,0.046236214,0.066095076,NA,10013538,Diverticulitis,10021881,Infections and infestations,Infec,secukinumab,DB09029
,1682588,DB11362,10016807,509,5974,166,2003,0.781635757,1.028091238,0.854667584,1.241473074,0.881110577,DB1136210016807_,0.126572148,0.027703916,NA,10016807,Fluid retention,10027433,Metabolism and nutrition disorders,Metab,selexipag,DB11362
,1682589,DB00448,10048302,52,5093,45,3079,0.09146933,0.698650328,0.458446945,1.06826839,0.19761405,DB0044810048302_,1.621439393,-0.358604908,NA,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,lansoprazole,DB00448
,1682748,DB11569,10046735,72,3413,22,2290,0.000908068,2.195603469,1.341479855,3.729188528,0.005089788,DB1156910046735_,5.280519078,0.786456938,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,ixekizumab,DB11569
,1682859,DB11362,10030124,328,6155,96,2073,0.250736459,1.150709158,0.908665078,1.468169019,0.410561707,DB1136210030124_,0.890229039,0.140378411,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1682867,DB11574,10019211,220,690,199,874,0.002389575,1.400073461,1.121436024,1.748824525,0.011248205,DB1157410019211_,4.487546711,0.336524707,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,elbasvir,DB11574
,1684824,DB00169,10061309,157,38534,26,18149,4.45313640144032e-08,2.843990701,1.868985237,4.490934554,8.69295880518818e-07,DB0016910061309_,13.95558229,1.045208242,female,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cholecalciferol,DB00169
,1684828,DB00531,10061309,48,7204,49,6467,0.541830467,0.879384472,0.577263728,1.338954028,0.697150876,DB0053110061309_,0.360753427,-0.12853308,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cyclophosphamide,DB00531
,1685655,DB11065,10022687,32,3154,24,2664,0.688194458,1.126148329,0.641033213,2.003353022,0.812014935,DB1106510022687_,0.208236546,0.118803252,NA,10022687,Intestinal obstruction,10017947,Gastrointestinal disorders,Gastr,pancrelipase amylase,DB11065
,1685701,DB00213,10028164,39,18856,15,13406,0.051964899,1.84847448,0.995796491,3.610781482,0.128742861,DB0021310028164_,2.04993819,0.614360693,NA,10028164,Multiple allergies,10021428,Immune system disorders,Immun,pantoprazole,DB00213
,1687407,DB06285,10062262,70,8780,20,1086,0.002040282,0.432987314,0.259090233,0.754606536,0.009883675,DB0628510062262_,4.616870902,-0.837046849,NA,10062262,Spinal operation,10042613,Surgical and medical procedures,Surg,teriparatide,DB06285
,1688179,DB09343,10047942,74,1445,78,1805,0.317294698,1.185013591,0.843627554,1.663288486,0.485100546,DB0934310047942_,0.723399098,0.169754243,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,tipiracil,DB09343
,1689648,DB11362,10042674,163,6320,48,2121,0.46964478,1.139626853,0.817990375,1.613293228,0.635943283,DB1136210042674_,0.452645897,0.130700887,NA,10042674,Swelling,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1689650,DB08932,10058920,42,19401,9,6588,0.259174486,1.584580386,0.759800659,3.704426505,0.420286427,DB0893210058920_,0.866818832,0.460319632,NA,10058920,Restless legs syndrome,10029205,Nervous system disorders,Nerv,macitentan,DB08932
,1689652,DB11362,10061105,57,6426,35,2134,0.005292713,0.540893214,0.347886228,0.851573549,0.021404564,DB1136210061105_,3.844151116,-0.614533406,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,selexipag,DB11362
,1691646,DB11362,10048959,360,6123,132,2037,0.362595671,0.907326572,0.736343002,1.12330956,0.53220767,DB1136210048959_,0.630721509,-0.097252836,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1691773,DB11362,10000060,184,6299,70,2099,0.377779612,0.875942047,0.658548727,1.175962862,0.547720732,DB1136210000060_,0.601989736,-0.132455347,NA,10000060,Abdominal distension,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1691996,DB11362,10005483,51,6432,37,2132,0.000463955,0.456928395,0.292494184,0.719848767,0.002901166,DB1136210005483_,5.842642613,-0.783228584,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,selexipag,DB11362
,1692009,DB11362,10007559,144,6339,54,2115,0.45643307,0.889754438,0.643786615,1.245114876,0.623805707,DB1136210007559_,0.471916327,-0.116809766,NA,10007559,Cardiac failure congestive,10007541,Cardiac disorders,Card,selexipag,DB11362
,1692043,DB11362,10049414,59,6424,20,2149,1,0.986855171,0.583991353,1.73452506,1,DB1136210049414_,0,-0.013231987,NA,10049414,Treatment noncompliance,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1692095,DB11362,10047513,57,6426,25,2144,0.251109951,0.760735351,0.466321237,1.274126095,0.41102786,DB1136210047513_,0.889094281,-0.273469746,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,selexipag,DB11362
,1692097,DB11362,10049848,38,6445,20,2149,0.126810769,0.63356713,0.358612941,1.151892721,0.251203638,DB1136210049848_,1.381491363,-0.456389319,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1692205,DB08895,10011878,45,28069,7,6639,0.378212538,1.520487481,0.680255193,3.99821231,0.548244448,DB0889510011878_,0.601034019,0.419030995,NA,10011878,Deafness,10013993,Ear and labyrinth disorders,Ear,tofacitinib,DB08895
,1692245,DB00374,10038647,51,17665,14,5710,0.666051085,1.177498997,0.641410704,2.305485691,0.796884442,DB0037410038647_,0.227045601,0.163392695,NA,10038647,Respiration abnormal,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,treprostinil,DB00374
,1694515,DB09564,10019211,37,1190,21,926,0.284115368,1.370832547,0.775655621,2.482756415,0.448627635,DB0956410019211_,0.801562056,0.315418254,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,insulin degludec,DB09564
,1695248,DB09303,10021688,51,26180,18,18941,0.007115785,2.049847327,1.177006335,3.729405197,0.027140449,DB0930310021688_,3.606730097,0.717765316,NA,10021688,Increased tendency to bruise,10005329,Blood and lymphatic system disorders,Blood,evolocumab,DB09303
,1695251,DB09303,10048592,73,26158,50,18909,0.784649582,1.055406908,0.726111001,1.544890368,0.883059927,DB0930310048592_,0.124362214,0.053926388,NA,10048592,Musculoskeletal disorder,10028395,Musculoskeletal and connective tissue disorders,Musc,evolocumab,DB09303
,1695277,DB09570,10061822,42,3859,30,3905,0.156276792,1.416619039,0.863798327,2.349294626,0.292427955,DB0957010061822_,1.229536951,0.348273074,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,1695278,DB05259,10066901,102,11168,12,2716,0.012536159,2.067033731,1.131317733,4.13744591,0.042636079,DB0525910066901_,3.155054466,0.726114599,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,glatiramer,DB05259
,1695394,DB09303,10005424,72,26159,117,18842,4.67488309890414e-08,0.443258143,0.325581009,0.599982625,9.08198834107134e-07,DB0930310005424_,13.9118025,-0.813602963,NA,10005424,Blood cholesterol decreased,10022891,Investigations,Inv,evolocumab,DB09303
,1695397,DB09303,10015916,37,26194,18,18941,0.174314266,1.486367364,0.824765053,2.774274463,0.31653544,DB0930310015916_,1.150320069,0.396335133,NA,10015916,Eye disorder,10015919,Eye disorders,Eye,evolocumab,DB09303
,1695477,DB09570,10021789,34,3867,26,3909,0.301997621,1.321844026,0.76843102,2.298673441,0.468305211,DB0957010021789_,0.758635036,0.279027751,NA,10021789,Infection,10021881,Infections and infestations,Infec,ixazomib,DB09570
,1696370,DB11362,10054112,503,5980,167,2002,0.962999418,1.008357853,0.838332684,1.217439082,1,DB1136210054112_,0,0.008323119,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,selexipag,DB11362
,1696371,DB11362,10055798,51,6432,25,2144,0.142446253,0.680033306,0.412462801,1.148384024,0.27323942,DB1136210055798_,1.297406873,-0.385613502,NA,10055798,Haemorrhage,10047065,Vascular disorders,Vasc,selexipag,DB11362
,1696406,DB09292,10028372,22,4507,45,8217,0.702598801,0.891320506,0.509031582,1.517907749,0.821576595,DB0929210028372_,0.196530108,-0.115051201,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,sacubitril,DB09292
,1696412,DB09303,10023547,79,26152,63,18896,0.60951182,0.906051609,0.642115685,1.283058762,0.751919637,DB0930310023547_,0.285125826,-0.098659011,NA,10023547,Laboratory test abnormal,10022891,Investigations,Inv,evolocumab,DB09303
,1696424,DB11362,10043071,67,6416,21,2148,0.901700288,1.068124943,0.644152361,1.840999946,0.957082614,DB1136210043071_,0.043865565,0.065904722,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,selexipag,DB11362
,1696765,DB11595,10013968,37,1076,40,994,0.561759996,0.854571359,0.526745972,1.383283216,0.714068308,DB1159510013968_,0.336776652,-0.157155271,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,atezolizumab,DB11595
,1700052,DB00524,10054112,64,1513,29,1315,0.004091748,1.917675915,1.210048908,3.105130285,0.017398948,DB0052410054112_,4.051345516,0.651113992,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,metolazone,DB00524
,1700413,DB11581,10021097,26,1727,41,2719,1,0.99840446,0.58404017,1.678678944,1,DB1158110021097_,0,-0.001596814,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,venetoclax,DB11581
,1700425,DB11581,10021789,24,1729,42,2718,0.704945607,0.898292879,0.518325769,1.524227424,0.823090269,DB1158110021789_,0.194689401,-0.107259118,NA,10021789,Infection,10021881,Infections and infestations,Infec,venetoclax,DB11581
,1704104,DB11362,10044565,80,6403,22,2147,0.490461888,1.219281429,0.750624805,2.058603711,0.653708774,DB1136210044565_,0.425093327,0.198261692,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1704441,DB08895,10044728,134,27980,40,6606,0.208362606,0.790931638,0.551270709,1.157219612,0.359251599,DB0889510044728_,1.023732303,-0.234543739,NA,10044728,Tuberculin test positive,10022891,Investigations,Inv,tofacitinib,DB08895
,1707141,DB06273,10066901,210,4885,46,1364,0.163283731,1.274656786,0.91687432,1.804599637,0.301792683,DB0627310066901_,1.198014978,0.242676955,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,1708409,DB11569,10016256,77,3408,37,2275,0.121827505,1.389142594,0.923272583,2.123315785,0.244011823,DB1156910016256_,1.410538599,0.328686718,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,1708410,DB11569,10025482,82,3403,40,2272,0.112585758,1.368602376,0.923045715,2.058493076,0.229948067,DB1156910025482_,1.469901792,0.313790056,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,1708411,DB11569,10028813,102,3383,55,2257,0.216223285,1.237225817,0.878732719,1.758000464,0.368886158,DB1156910028813_,0.997267196,0.212871629,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,ixekizumab,DB11569
,1709638,DB09263,10012735,113,1278,121,1599,0.274055987,1.16838959,0.886333012,1.539383114,0.43714911,DB0926310012735_,0.827480929,0.155626382,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,patiromer,DB09263
,1709865,DB09263,10010774,152,1239,213,1507,0.21797866,0.868012184,0.690709382,1.088926052,0.371182241,DB0926310010774_,0.991062121,-0.141549528,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,patiromer,DB09263
,1711222,DB08932,10077512,31,19412,21,6576,0.016303403,0.500066848,0.278093298,0.916371969,0.052597111,DB0893210077512_,2.945094088,-0.693013493,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,macitentan,DB08932
,1711632,DB11362,10028596,43,6440,15,2154,0.879615679,0.958821782,0.520918955,1.861957927,0.949457398,DB1136210028596_,0.051864617,-0.042050059,NA,10028596,Myocardial infarction,10007541,Cardiac disorders,Card,selexipag,DB11362
,1713913,DB01075,10044066,29,19919,41,11056,0.00013705,0.392605465,0.235167431,0.647672562,0.001043863,DB0107510044066_,6.864827377,-0.934950078,NA,10044066,Torsade de pointes,10007541,Cardiac disorders,Card,diphenhydramine,DB01075
,1726746,DB09303,10069853,244,25987,108,18851,1.34936843607306e-05,1.638847882,1.30034513,2.076817028,0.000141307,DB0930310069853_,8.864573126,0.493993484,NA,10069853,Device difficult to use,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,1731140,DB00688,10076308,190,6300,109,5269,0.001796941,1.457807686,1.142470487,1.867846692,0.008906771,DB0068810076308_,4.720943492,0.376933722,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,mycophenolate mofetil,DB00688
,1731219,DB11362,10021789,106,6377,25,2144,0.127255783,1.425436711,0.912101134,2.307519639,0.251800531,DB1136210021789_,1.379118047,0.354478231,NA,10021789,Infection,10021881,Infections and infestations,Infec,selexipag,DB11362
,1731230,DB11362,10037324,57,6426,12,2157,0.163236432,1.594286727,0.843846228,3.270950113,0.301734853,DB1136210037324_,1.198206619,0.466426443,NA,10037324,Pulmonary arterial pressure increased,10022891,Investigations,Inv,selexipag,DB11362
,1731233,DB11362,10037844,144,6339,63,2106,0.074341916,0.75940652,0.558536707,1.042409874,0.168767738,DB1136210037844_,1.779231838,-0.275218046,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,selexipag,DB11362
,1735182,DB11362,10036653,82,6401,22,2147,0.425438953,1.250148262,0.770858528,2.108126337,0.594174591,DB1136210036653_,0.520582079,0.223262154,NA,10036653,Presyncope,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1738057,DB11581,10013709,32,1721,56,2704,0.660198786,0.897819632,0.560160528,1.417111839,0.792537212,DB1158110013709_,0.232515819,-0.107786086,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,venetoclax,DB11581
,1738062,DB11581,10016173,21,1732,31,2729,0.886398848,1.067349614,0.580930758,1.924931426,0.952748725,DB1158110016173_,0.048404077,0.06517858,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,venetoclax,DB11581
,1740690,DB00007,10012587,10,1937,274,4178,6.42371982669404e-32,0.078736101,0.037254909,0.147472211,1.63137657627684e-29,DB0000710012587_,66.28554351,-2.541653516,male,10012587,Device leakage,10077536,Product issues,Prod,leuprolide,DB00007
,1742890,DB09564,10047899,37,1190,21,926,0.284115368,1.370832547,0.775655621,2.482756415,0.448627635,DB0956410047899_,0.801562056,0.315418254,NA,10047899,Weight increased,10022891,Investigations,Inv,insulin degludec,DB09564
,1742900,DB09564,10048959,31,1196,23,924,1,1.041284193,0.583360323,1.883763367,1,DB0956410048959_,0,0.040454752,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,insulin degludec,DB09564
,1743016,DB09564,10028813,61,1166,43,904,0.685786036,1.099831641,0.724691307,1.681607632,0.810316062,DB0956410028813_,0.210330908,0.095157114,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,insulin degludec,DB09564
,1744475,DB09303,10012174,61,26170,27,18932,0.039328229,1.634380958,1.022693306,2.675984151,0.104297281,DB0930310012174_,2.260509986,0.491264114,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,evolocumab,DB09303
,1746165,DB00704,10008796,21,4335,35,5159,0.229466883,0.714074463,0.394334106,1.263475754,0.385254025,DB0070410008796_,0.953852358,-0.336768033,NA,10008796,Chromaturia,10038359,Renal and urinary disorders,Renal,naltrexone,DB00704
,1747020,DB11362,10040753,125,6358,16,2153,7.39052256352316e-05,2.645478151,1.562121518,4.782014498,0.000614746,DB1136210040753_,7.394300614,0.972851824,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,selexipag,DB11362
,1750812,DB11569,10022052,40,3445,21,2291,0.431473096,1.266653789,0.727094426,2.267520626,0.599908507,DB1156910022052_,0.510978123,0.236378611,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,1750813,DB11569,10022086,192,3293,109,2203,0.184238334,1.17835819,0.920687949,1.514252909,0.329240275,DB1156910022086_,1.110967475,0.164122105,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,1753460,DB08930,10071404,67,390,34,833,1.32733856352911e-11,4.203941712,2.690781032,6.672032317,4.95583723613105e-10,DB0893010071404_,21.42528481,1.436022588,female,10071404,Foetal exposure during pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,dolutegravir,DB08930
,1753838,DB11581,10053762,248,1505,381,2379,0.757666869,1.028937548,0.862082167,1.226586033,0.86456582,DB1158110053762_,0.145527841,0.028526763,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,venetoclax,DB11581
,1754525,DB11362,10061024,101,6382,30,2139,0.612510323,1.128359639,0.741756535,1.76284236,0.754417876,DB1136210061024_,0.281808852,0.120764931,NA,10061024,Cardiac disorder,10007541,Cardiac disorders,Card,selexipag,DB11362
,1755895,DB11362,10015090,114,6369,28,2141,0.144162728,1.368579157,0.895692307,2.156418745,0.275797322,DB1136210015090_,1.288089022,0.31377309,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1756351,DB11362,10018836,49,6434,23,2146,0.174224331,0.710616957,0.423603926,1.225158496,0.316459577,DB1136210018836_,1.150559764,-0.341621733,NA,10018836,Haematochezia,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1756477,DB00704,10022093,75,4281,25,5169,3.12861303177697e-09,3.62182679,2.27164215,5.957803417,7.88074686538166e-08,DB0070410022093_,16.35625806,1.286978537,female,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,1756943,DB09570,10019974,34,3867,23,3912,0.145005918,1.495378979,0.85375526,2.66413556,0.277067609,DB0957010019974_,1.283493728,0.402379672,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,ixazomib,DB09570
,1758368,DB08895,10044755,87,28027,25,6621,0.399160967,0.822108024,0.521352054,1.340204372,0.569019115,DB0889510044755_,0.563841252,-0.195883477,NA,10044755,Tuberculosis,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,1759815,DB00704,10015535,27,4329,51,5143,0.05269209,0.628990483,0.378522186,1.02393624,0.130084679,DB0070410015535_,2.039569666,-0.463639153,NA,10015535,Euphoric mood,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,1759827,DB00704,10044565,117,4239,115,5079,0.142307553,1.218967741,0.931081567,1.596056346,0.273023177,DB0070410044565_,1.29819859,0.198004386,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,naltrexone,DB00704
,1763295,DB00863,10077512,39,10634,46,5794,0.000554098,0.461958537,0.293267797,0.724470065,0.003360899,DB0086310077512_,5.695546701,-0.772280138,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,ranitidine,DB00863
,1769883,DB11362,10016766,78,6405,18,2151,0.191890828,1.455176026,0.860918291,2.588540843,0.339036796,DB1136210016766_,1.081646635,0.375126873,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1769885,DB11362,10017944,99,6384,29,2140,0.607494427,1.144328298,0.747453922,1.801340985,0.750427549,DB1136210017944_,0.287112169,0.134817825,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1769912,DB11362,10046571,178,6305,24,2145,3.45191260015069e-06,2.52317881,1.636622767,4.053105966,4.27081773099369e-05,DB1136210046571_,10.06112015,0.925519539,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,selexipag,DB11362
,1769923,DB11362,10060800,53,6430,7,2162,0.015912067,2.545723434,1.150963674,6.648255796,0.051616522,DB1136210060800_,2.963913456,0.934414866,NA,10060800,Hot flush,10047065,Vascular disorders,Vasc,selexipag,DB11362
,1770798,DB11362,10022000,173,6310,50,2119,0.389503711,1.161900844,0.840173364,1.631687779,0.559382874,DB1136210022000_,0.580921114,0.150057322,NA,10022000,Influenza,10021881,Infections and infestations,Infec,selexipag,DB11362
,1772285,DB14185,10022086,99,465,92,541,0.155814137,1.251720738,0.907396556,1.728048384,0.291884302,DB1418510022086_,1.231397782,0.224519195,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,aripiprazole lauroxil,DB14185
,1772289,DB00557,10022081,38,5949,13,3054,0.23656591,1.500538638,0.780473746,3.074710769,0.393819111,DB0055710022081_,0.931863583,0.405824135,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,hydroxyzine,DB00557
,1772292,DB14185,10022081,52,512,19,614,6.64018638272299e-06,3.278965362,1.877663035,5.953538403,7.58692888806232e-05,DB1418510022081_,9.486498582,1.187527934,female,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,aripiprazole lauroxil,DB14185
,1773674,DB09570,10003239,30,3871,26,3909,0.593918005,1.165149145,0.664662337,2.055081279,0.739951879,DB0957010003239_,0.301170123,0.152849101,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ixazomib,DB09570
,1774339,DB06273,10001551,27,5068,55,1355,8.68398573008745e-19,0.131306772,0.079337596,0.212675974,8.06567367192045e-17,DB0627310001551_,37.05632934,-2.030218923,male,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,tocilizumab,DB06273
,1774343,DB06273,10003481,19,5076,44,1366,2.67912576519351e-16,0.116258199,0.063882497,0.204089663,1.91101277443993e-14,DB0627310003481_,31.58855795,-2.151941705,male,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,tocilizumab,DB06273
,1774346,DB01281,10077692,55,8877,8,1790,0.498312733,1.386266548,0.655018055,3.376474804,0.660264011,DB0128110077692_,0.415115508,0.326614197,NA,10077692,Liver function test increased,10022891,Investigations,Inv,abatacept,DB01281
,1775148,DB11362,10046306,79,6404,10,2159,0.001890082,2.66327484,1.371390653,5.778802671,0.009289168,DB1136210046306_,4.678906336,0.979556509,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,selexipag,DB11362
,1776270,DB08907,10031252,41,4212,121,3789,2.81582845485485e-12,0.304855133,0.207926395,0.439055334,1.17763008648942e-10,DB0890710031252_,22.86234691,-1.187918589,male,10031252,Osteomyelitis,10021881,Infections and infestations,Infec,canagliflozin,DB08907
,1777341,DB09331,10003658,23,2062,33,2396,0.500887534,0.80990216,0.452485321,1.426792524,0.662364986,DB0933110003658_,0.411938536,-0.210841828,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,daratumumab,DB09331
,1781950,DB09303,10005554,35,26196,29,18930,0.613349368,0.87214375,0.517695128,1.479687185,0.7550882,DB0930310005554_,0.280920716,-0.136801018,NA,10005554,Blood glucose abnormal,10022891,Investigations,Inv,evolocumab,DB09303
,1783421,DB11362,10047571,48,6435,15,2154,0.884964897,1.07113351,0.588217886,2.063837105,0.952079302,DB1136210047571_,0.049106947,0.068717443,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,selexipag,DB11362
,1784342,DB11362,10020751,48,6435,12,2157,0.454835444,1.34073211,0.699961349,2.77809254,0.622431324,DB1136210020751_,0.474121979,0.293215815,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,selexipag,DB11362
,1786620,DB11362,10015150,69,6414,21,2148,0.806978608,1.100348085,0.664997001,1.893391156,0.895696333,DB1136210015150_,0.110153837,0.095626571,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,selexipag,DB11362
,1787995,DB11362,10041349,105,6378,50,2119,0.039832274,0.697726871,0.491715539,1.001434727,0.105350366,DB1136210041349_,2.250463667,-0.359927554,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1788699,DB11362,10037423,132,6351,43,2126,0.929933703,1.02761563,0.720541186,1.490885277,0.971263679,DB1136210037423_,0.029157294,0.027241196,NA,10037423,Pulmonary oedema,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1791158,DB00704,10022075,236,4120,140,5054,1.27473276079995e-11,2.067727538,1.663431341,2.577700993,4.77638640308293e-10,DB0070410022075_,21.46216665,0.726450197,NA,10022075,Injection site induration,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,1799337,DB01137,10029350,41,7731,36,5557,0.417869908,0.818644414,0.509631035,1.320212706,0.58692479,DB0113710029350_,0.532858593,-0.20010546,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,levofloxacin,DB01137
,1799945,DB00993,10066901,68,3181,6,1613,5.70682113330168e-07,5.746012552,2.50003402,16.23709827,8.71608329394739e-06,DB0099310066901_,11.65034058,1.748506145,female,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,azathioprine,DB00993
,1805558,DB09292,10005746,14,4515,47,8215,0.044016041,0.541999554,0.275263781,1.002718381,0.113622553,DB0929210005746_,2.174873267,-0.6124901,NA,10005746,Blood pressure fluctuation,10047065,Vascular disorders,Vasc,sacubitril,DB09292
,1805564,DB09292,10012601,34,4495,56,8206,0.658754906,1.108378025,0.70059392,1.730311295,0.791600722,DB0929210012601_,0.233698153,0.102897708,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,sacubitril,DB09292
,1805724,DB09292,10027175,80,4449,109,8153,0.046584917,1.344912856,0.992600348,1.815835323,0.118663101,DB0929210027175_,2.131466881,0.29632922,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,sacubitril,DB09292
,1806340,DB11362,10038435,75,6408,35,2134,0.120290688,0.713647139,0.470185919,1.102032819,0.241774031,DB1136210038435_,1.419751745,-0.337366642,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,selexipag,DB11362
,1806481,DB11362,10039101,64,6419,24,2145,0.622003638,0.891103603,0.548022295,1.493875062,0.762190421,DB1136210039101_,0.271558858,-0.115294581,NA,10039101,Rhinorrhoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1809350,DB11362,10017885,117,6366,31,2138,0.292321653,1.267505906,0.844002915,1.955257632,0.45789307,DB1136210017885_,0.781119594,0.237051116,NA,10017885,Gastrooesophageal reflux disease,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1809405,DB00688,10015108,33,6457,36,5342,0.275762408,0.758398892,0.45755998,1.253276862,0.439045089,DB0068810015108_,0.823153164,-0.276545789,NA,10015108,Epstein-Barr virus infection,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,1810331,DB11574,10028813,142,768,119,954,0.003333149,1.481953709,1.131712606,1.943194847,0.014724676,DB1157410028813_,4.218230574,0.393361291,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,elbasvir,DB11574
,1810340,DB11574,10047700,35,875,26,1047,0.069198366,1.610359055,0.933789998,2.809484176,0.159887398,DB1157410047700_,1.833285472,0.47645717,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,elbasvir,DB11574
,1810782,DB00905,10066901,351,2367,210,715,7.24622068900935e-12,0.504984491,0.415828456,0.614161086,2.83643947595846e-10,DB0090510066901_,21.98330137,-0.683227562,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,bimatoprost,DB00905
,1812463,DB00704,10017944,20,4336,32,5162,0.330343963,0.74408515,0.402705542,1.343750114,0.499042563,DB0070410017944_,0.69506389,-0.295599801,NA,10017944,Gastrointestinal disorder,10017947,Gastrointestinal disorders,Gastr,naltrexone,DB00704
,1815399,DB00704,10002942,25,4331,49,5145,0.046005212,0.606127859,0.358092124,1.002486347,0.117493879,DB0070410002942_,2.141369041,-0.500664327,NA,10002942,Apathy,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,1818623,DB11362,10042209,45,6438,7,2162,0.054340605,2.158802807,0.964445817,5.682324164,0.13312771,DB1136210042209_,2.016446384,0.769553812,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,selexipag,DB11362
,1819794,DB11595,10016288,38,1075,45,989,0.265059039,0.776983513,0.486431551,1.23536707,0.42703505,DB1159510016288_,0.850889184,-0.252336147,NA,10016288,Febrile neutropenia,10005329,Blood and lymphatic system disorders,Blood,atezolizumab,DB11595
,1821010,DB11915,10010305,51,2280,16,1359,0.029237147,1.899618109,1.060740246,3.583887912,0.083018084,DB1191510010305_,2.48869681,0.641652871,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,valbenazine,DB11915
,1821346,DB09029,10002556,31,11313,19,7251,1,1.045752544,0.571914485,1.96080465,1,DB0902910002556_,0,0.044736764,NA,10002556,Ankylosing spondylitis,10028395,Musculoskeletal and connective tissue disorders,Musc,secukinumab,DB09029
,1821883,DB11362,10064355,46,6437,23,2146,0.124498138,0.666804703,0.394866705,1.155450485,0.247817764,DB1136210064355_,1.395061627,-0.405258074,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,selexipag,DB11362
,1822241,DB06605,10051076,34,14039,16,13017,0.023568797,1.970250822,1.057664228,3.824579989,0.070218853,DB0660510051076_,2.656138438,0.678160855,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,1823311,DB00836,10048610,22,5513,30,4045,0.033831927,0.538108196,0.295283813,0.96619171,0.093039237,DB0083610048610_,2.374733977,-0.619695632,NA,10048610,Cardiotoxicity,10007541,Cardiac disorders,Card,loperamide,DB00836
,1825057,DB09029,10061822,41,11303,11,7259,0.009678119,2.393616856,1.207338122,5.167702697,0.034672121,DB0902910061822_,3.36181933,0.872805551,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,1825066,DB05316,10011224,16,4340,42,6953,0.104198238,0.610339096,0.319910348,1.110218856,0.217337928,DB0531610011224_,1.526301863,-0.493740581,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pimavanserin,DB05316
,1825072,DB05316,10013642,13,4343,45,6950,0.014115257,0.46233118,0.228537938,0.87330401,0.046905026,DB0531610013642_,3.059630443,-0.771473804,NA,10013642,Drooling,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,1825078,DB05316,10013950,66,4290,122,6873,0.365225546,0.866693114,0.630825067,1.181896658,0.534854672,DB0531610013950_,0.625760211,-0.143070327,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,pimavanserin,DB05316
,1825079,DB05316,10013968,75,4281,70,6925,0.001055105,1.733000822,1.231538991,2.441427004,0.005760395,DB0531610013968_,5.156749174,0.549854485,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,pimavanserin,DB05316
,1825091,DB05316,10024264,36,4320,74,6921,0.238026363,0.77941901,0.507281984,1.178243724,0.395531859,DB0531610024264_,0.92752394,-0.249206495,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,1825647,DB01073,10063620,37,1028,33,1617,0.024875476,1.763173032,1.06523627,2.929714887,0.073223795,DB0107310063620_,2.614234847,0.567115045,NA,10063620,Acute lymphocytic leukaemia recurrent,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fludarabine,DB01073
,1829419,DB00704,10039203,37,4319,56,5138,0.295600735,0.786024159,0.503393669,1.214500619,0.461434529,DB0070410039203_,0.7734151,-0.24076775,NA,10039203,Road traffic accident,10022117,"Injury, poisoning and procedural complications",Inj&P,naltrexone,DB00704
,1829983,DB09029,10034839,37,11307,15,7255,0.154697805,1.582668788,0.847174736,3.106438734,0.290378579,DB0902910034839_,1.236569763,0.459112529,NA,10034839,Pharyngitis streptococcal,10021881,Infections and infestations,Infec,secukinumab,DB09029
,1830417,DB11362,10007882,66,6417,17,2152,0.374675897,1.301931336,0.753001554,2.372698541,0.544536523,DB1136210007882_,0.607820262,0.263848805,NA,10007882,Cellulitis,10021881,Infections and infestations,Infec,selexipag,DB11362
,1830518,DB11362,10034474,74,6409,22,2147,0.722553355,1.126793589,0.690078156,1.910108181,0.836665856,DB1136210034474_,0.178330504,0.119376067,NA,10034474,Pericardial effusion,10007541,Cardiac disorders,Card,selexipag,DB11362
,1830551,DB11362,10053483,52,6431,9,2160,0.074083779,1.940582878,0.94549583,4.486787834,0.168359193,DB1136210053483_,1.78165553,0.662988381,NA,10053483,Infusion site pain,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1832882,DB14185,10016256,37,527,45,588,0.732185851,0.917483855,0.567795556,1.4746889,0.844415905,DB1418510016256_,0.169110128,-0.086120296,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,aripiprazole lauroxil,DB14185
,1836209,DB01224,10014522,39,8069,26,5891,0.801600848,1.095133907,0.64916214,1.875971527,0.892668641,DB0122410014522_,0.11353983,0.090876645,NA,10014522,Embolism venous,10047065,Vascular disorders,Vasc,quetiapine,DB01224
,1840613,DB11362,10012378,74,6409,28,2141,0.566666926,0.882904064,0.562768129,1.420984514,0.717996633,DB1136210012378_,0.331290399,-0.124538732,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,selexipag,DB11362
,1841090,DB09570,10054112,35,3866,44,3891,0.366114767,0.800622757,0.497347347,1.280134457,0.53571557,DB0957010054112_,0.624151911,-0.222365408,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,ixazomib,DB09570
,1843598,DB01073,10018838,57,1008,107,1543,0.248314115,0.815511461,0.574832677,1.147043329,0.407674563,DB0107310018838_,0.897286064,-0.203939803,NA,10018838,Haematocrit decreased,10022891,Investigations,Inv,fludarabine,DB01073
,1843797,DB00688,10025327,15,6475,35,5343,0.000522659,0.353675059,0.179275469,0.665403232,0.003202229,DB0068810025327_,5.74390829,-1.0393767,male,10025327,Lymphopenia,10005329,Blood and lymphatic system disorders,Blood,mycophenolate mofetil,DB00688
,1844345,DB11362,10068319,88,6395,15,2154,0.011687577,1.976013286,1.132224319,3.687545119,0.040316005,DB1136210068319_,3.211006736,0.681081323,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1845425,DB09292,10049040,23,4506,44,8218,0.89875938,0.953345869,0.548763274,1.615733424,0.95647837,DB0929210049040_,0.044497104,-0.047777514,NA,10049040,Weight fluctuation,10027433,Metabolism and nutrition disorders,Metab,sacubitril,DB09292
,1845445,DB11362,10005724,64,6419,15,2154,0.241362876,1.431663916,0.804655524,2.711203567,0.399472544,DB1136210005724_,0.917610242,0.358837345,NA,10005724,Blood potassium decreased,10022891,Investigations,Inv,selexipag,DB11362
,1845492,DB00512,10077692,18,4719,35,5063,0.03931161,0.551810154,0.293804294,1.002665186,0.104263727,DB0051210077692_,2.260831757,-0.594551215,NA,10077692,Liver function test increased,10022891,Investigations,Inv,vancomycin,DB00512
,1845843,DB09292,10022000,28,4501,50,8212,0.906130297,1.021721657,0.618408974,1.657265212,0.958128401,DB0929210022000_,0.04277348,0.021489104,NA,10022000,Influenza,10021881,Infections and infestations,Infec,sacubitril,DB09292
,1846860,DB08879,10065154,68,1210,6,107,1,1.00220228,0.423391253,2.892575786,1,DB0887910065154_,0,0.002199858,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,belimumab,DB08879
,1846889,DB00704,10048010,98,4258,144,5050,0.116573744,0.80715953,0.615876322,1.054223305,0.235993596,DB0070410048010_,1.443950609,-0.214233947,NA,10048010,Withdrawal syndrome,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,1846893,DB00704,10048921,35,4321,62,5132,0.064968331,0.670497996,0.42899953,1.033096768,0.152397699,DB0070410048921_,1.881261736,-0.399734566,NA,10048921,Alcohol use,10041244,Social circumstances,SocCi,naltrexone,DB00704
,1847380,DB00182,10036495,61,5133,11,2841,0.000174624,3.068935077,1.59715448,6.479055794,0.001286072,DB0018210036495_,6.656162321,1.121330621,female,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,amphetamine,DB00182
,1849351,DB11574,10012735,67,843,76,997,0.861777973,1.042625174,0.729478326,1.48738699,0.935523646,DB1157410012735_,0.066648858,0.041741738,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,elbasvir,DB11574
,1849501,DB11569,10022061,198,3287,87,2225,0.000978993,1.540440347,1.183985223,2.017418155,0.005411172,DB1156910022061_,5.219289654,0.432068315,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,1849502,DB11569,10022112,56,3429,14,2298,0.000505046,2.68025478,1.468246479,5.226015201,0.003114197,DB1156910022112_,5.771784035,0.985911857,NA,10022112,Injection site warmth,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,1849503,DB11569,10053425,146,3339,56,2256,0.000317734,1.761353593,1.279470499,2.453626301,0.00211434,DB1156910053425_,6.159012403,0.5660826,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,1849884,DB01137,10077361,30,7742,26,5567,0.499750833,0.829706246,0.473718406,1.46228893,0.661494141,DB0113710077361_,0.413254153,-0.186683561,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,levofloxacin,DB01137
,1850290,DB00193,10061309,47,19273,19,8683,0.790316311,1.114453065,0.641213142,2.012165857,0.886410114,DB0019310061309_,0.120575553,0.108363759,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,tramadol,DB00193
,1852890,DB08868,10024217,56,9146,10,2501,0.291033296,1.531267156,0.772659874,3.371363398,0.456432589,DB0886810024217_,0.78431426,0.426095599,NA,10024217,Lentigo,10040785,Skin and subcutaneous tissue disorders,Skin,fingolimod,DB08868
,1852904,DB08868,10039796,107,9095,22,2489,0.237270004,1.330978036,0.833348039,2.217350308,0.394611792,DB0886810039796_,0.929852802,0.285914037,NA,10039796,Seborrhoeic keratosis,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fingolimod,DB08868
,1853158,DB08895,10073753,85,28029,17,6629,0.614412768,1.182518862,0.696324355,2.125471455,0.75590169,DB0889510073753_,0.27984395,0.167646792,NA,10073753,Fear of injection,10037175,Psychiatric disorders,Psych,tofacitinib,DB08895
,1853764,DB01097,10077692,117,6148,20,1483,0.189610588,1.411052537,0.869754201,2.402970153,0.336026214,DB0109710077692_,1.090566105,0.344335906,NA,10077692,Liver function test increased,10022891,Investigations,Inv,leflunomide,DB01097
,1856180,DB00193,10077512,19,19301,36,8666,1.89678969301207e-07,0.236956389,0.128309551,0.424516619,3.23852660479522e-06,DB0019310077512_,12.64039208,-1.439879166,male,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,tramadol,DB00193
,1857188,DB11362,10062244,43,6440,7,2162,0.072936008,2.062220309,0.917906471,5.441216874,0.16642176,DB1136210062244_,1.793229989,0.723783222,NA,10062244,Sinus disorder,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1857880,DB00669,10070691,122,6255,18,1079,0.629757801,1.16915674,0.705913922,2.047442086,0.768820013,DB0066910070691_,0.262898391,0.156282754,NA,10070691,Device deployment issue,10077536,Product issues,Prod,sumatriptan,DB00669
,1858597,DB11362,10042682,41,6442,11,2158,0.63060633,1.248556939,0.62886994,2.698419782,0.76948551,DB1136210042682_,0.262033156,0.221988436,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1860390,DB11362,10047899,217,6266,74,2095,0.890608549,0.980443009,0.746041465,1.300539271,0.954671384,DB1136210047899_,0.046388098,-0.01975076,NA,10047899,Weight increased,10022891,Investigations,Inv,selexipag,DB11362
,1860592,DB01073,10077361,23,1042,50,1600,0.183034195,0.706421113,0.408781573,1.187718281,0.327697604,DB0107310077361_,1.115664035,-0.347543742,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,fludarabine,DB01073
,1861699,DB09303,10061520,58,26173,32,18927,0.240257135,1.310700501,0.836759026,2.086700905,0.398143858,DB0930310061520_,0.920941887,0.270561728,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,1862102,DB01224,10073085,22,8086,51,5866,2.1203662433541e-06,0.312965037,0.180525843,0.526077254,2.79120613488681e-05,DB0122410073085_,10.48645166,-1.161663797,male,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,1862831,DB00704,10002368,21,4335,38,5156,0.148793418,0.65732341,0.365898991,1.15083234,0.282313855,DB0070410002368_,1.264735865,-0.419579129,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,1862882,DB09570,10062355,40,3861,39,3896,0.910301065,1.034943026,0.647404112,1.655784481,0.959579421,DB0957010062355_,0.041260194,0.034346378,NA,10062355,Unevaluable event,10018065,General disorders and administration site conditions,Genrl,ixazomib,DB09570
,1864161,DB09029,10012587,37,11307,28,7242,0.525672268,0.846372142,0.503626749,1.437155532,0.683601512,DB0902910012587_,0.380380116,-0.166796132,NA,10012587,Device leakage,10077536,Product issues,Prod,secukinumab,DB09029
,1865473,DB06605,10033661,25,14048,32,13001,0.234692254,0.723035958,0.410550771,1.259984937,0.39156342,DB0660510033661_,0.937607784,-0.324296323,NA,10033661,Pancytopenia,10005329,Blood and lymphatic system disorders,Blood,apixaban,DB06605
,1867775,DB08907,10024124,19,4234,40,3870,0.002417833,0.434204772,0.237086405,0.768962235,0.01135783,DB0890710024124_,4.477847897,-0.834239032,NA,10024124,Leg amputation,10042613,Surgical and medical procedures,Surg,canagliflozin,DB08907
,1867854,DB09292,10002855,32,4497,42,8220,0.179627486,1.392583793,0.849607223,2.262925561,0.32339099,DB0929210002855_,1.128893191,0.331160865,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,sacubitril,DB09292
,1871310,DB11362,10003445,79,6404,36,2133,0.129288458,0.730938971,0.485327126,1.119848482,0.254576907,DB1136210003445_,1.368152301,-0.31342531,NA,10003445,Ascites,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,1874259,DB00005,10051082,1007,127075,360,42059,0.209148081,0.925811117,0.819588537,1.047690768,0.360196652,DB0000510051082_,1.02110514,-0.077085043,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,1875728,DB00722,10078504,17,25386,45,25987,0.000522499,0.386701336,0.207449125,0.689293396,0.003201746,DB0072210078504_,5.744058963,-0.950102624,NA,10078504,Contraindicated product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,1875731,DB09292,10078504,26,4503,77,8185,0.029974375,0.613782885,0.377018133,0.970115929,0.084658728,DB0929210078504_,2.469127066,-0.488114021,NA,10078504,Contraindicated product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,sacubitril,DB09292
,1876589,DB06605,10039163,51,14022,17,13016,0.000130204,2.784475043,1.580703693,5.146842624,0.000998663,DB0660510039163_,6.909093117,1.024059361,female,10039163,Right ventricular failure,10007541,Cardiac disorders,Card,apixaban,DB06605
,1877772,DB00959,10071066,56,8022,10,4992,6.03899273266219e-05,3.484538511,1.759291188,7.666125119,0.000518742,DB0095910071066_,7.564104715,1.248335614,female,10071066,Posterior reversible encephalopathy syndrome,10029205,Nervous system disorders,Nerv,methylprednisolone,DB00959
,1877894,DB14185,10047899,59,505,43,590,0.029032531,1.602383857,1.043219449,2.47797545,0.08255748,DB1418510047899_,2.494260504,0.471492431,NA,10047899,Weight increased,10022891,Investigations,Inv,aripiprazole lauroxil,DB14185
,1878253,DB11362,10003658,146,6337,41,2128,0.348463511,1.195766147,0.83725039,1.741076661,0.518039476,DB1136210003658_,0.657703832,0.178787107,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,selexipag,DB11362
,1879363,DB01413,10038540,21,1199,33,1626,0.677424559,0.863051238,0.471942431,1.545584427,0.804468443,DB0141310038540_,0.217573538,-0.147281218,NA,10038540,Renal tubular necrosis,10038359,Renal and urinary disorders,Renal,cefepime,DB01413
,1879858,DB05676,10051082,612,46517,402,24927,0.001813896,0.81581556,0.717455114,0.928402175,0.008978108,DB0567610051082_,4.71296609,-0.203566979,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,1880114,DB00158,10051082,56,16759,29,8075,0.729574506,0.930435819,0.583591919,1.512495926,0.842472184,DB0015810051082_,0.171414633,-0.07210218,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,folic acid,DB00158
,1880115,DB00563,10051082,295,46351,100,15248,0.815047214,0.970454763,0.770379786,1.231034908,0.900734345,DB0056310051082_,0.104544909,-0.02999049,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,1880432,DB00704,10042609,39,4317,23,5171,0.006962752,2.030917172,1.181075689,3.567927708,0.026684157,DB0070410042609_,3.623685253,0.7084875,NA,10042609,Surgery,10042613,Surgical and medical procedures,Surg,naltrexone,DB00704
,1881795,DB05316,10019063,934,3422,1677,5318,0.001816141,0.865541398,0.789425954,0.948672225,0.008986682,DB0531610019063_,4.712011598,-0.144400075,NA,10019063,Hallucination,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,1881798,DB05316,10022437,117,4239,202,6793,0.559395784,0.928177259,0.730298796,1.175343486,0.712147924,DB0531610022437_,0.33946963,-0.074532552,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,1881826,DB05316,10013709,578,3778,725,6270,3.05040666782183e-06,1.323046591,1.175315256,1.488958475,3.84740591476472e-05,DB0531610013709_,10.16552633,0.2799371,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,1881827,DB05316,10016173,306,4050,474,6521,0.620017799,1.039475111,0.892490623,1.209261077,0.760590276,DB0531610016173_,0.273660469,0.038715885,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,pimavanserin,DB05316
,1881932,DB05316,10010305,295,4061,686,6309,1.64590074990869e-08,0.668098891,0.577588155,0.77139495,3.51156665676541e-07,DB0531610010305_,14.86203337,-0.403319076,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,1881933,DB05316,10012735,52,4304,81,6914,0.858128545,1.031294783,0.712009145,1.48228446,0.932274228,DB0531610012735_,0.070128272,0.030815083,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,pimavanserin,DB05316
,1882105,DB05316,10010264,66,4290,132,6863,0.161138382,0.79991289,0.58451624,1.085754026,0.299013227,DB0531610010264_,1.207267469,-0.223252445,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,1882110,DB05316,10012239,183,4173,365,6630,0.014979152,0.796589339,0.66048039,0.958127262,0.049252815,DB0531610012239_,3.010788764,-0.227415992,NA,10012239,Delusion,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,1882888,DB09570,10071134,37,3864,47,3888,0.32390897,0.792148965,0.499380864,1.248190226,0.492320656,DB0957010071134_,0.708625035,-0.233005818,NA,10071134,Product physical issue,10077536,Product issues,Prod,ixazomib,DB09570
,1882895,DB01240,10013969,63,5688,13,1563,0.401453424,1.33161381,0.723084986,2.644823038,0.571258216,DB0124010013969_,0.559913955,0.286391598,NA,10013969,Dyspnoea at rest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,epoprostenol,DB01240
,1883098,DB11581,10047942,54,1699,75,2685,0.521304263,1.137809004,0.782417542,1.645329593,0.680135498,DB1158110047942_,0.38546324,0.129104487,NA,10047942,White blood cell count decreased,10022891,Investigations,Inv,venetoclax,DB11581
,1883311,DB09263,10061105,32,1359,61,1659,0.044464964,0.640484047,0.401414436,1.004818937,0.114528327,DB0926310061105_,2.166933088,-0.445531065,NA,10061105,Dialysis,10042613,Surgical and medical procedures,Surg,patiromer,DB09263
,1883316,DB09263,10047700,57,1334,46,1674,0.033863566,1.554704188,1.028352716,2.361570104,0.093111966,DB0926310047700_,2.373952575,0.441285295,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,patiromer,DB09263
,1883354,DB09263,10011906,257,1134,397,1323,0.001937657,0.755318489,0.63067636,0.903582213,0.009487633,DB0926310011906_,4.657766118,-0.280615779,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,patiromer,DB09263
,1883407,DB00820,10051082,155,11760,53,5763,0.025606327,1.433140793,1.041044639,1.999851026,0.074851235,DB0082010051082_,2.59225267,0.359868395,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,tadalafil,DB00820
,1883408,DB11362,10051082,182,6301,69,2100,0.375351522,0.879115917,0.659697461,1.182640123,0.545239831,DB1136210051082_,0.606529524,-0.128838516,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1883519,DB09570,10017413,58,3843,68,3867,0.41958097,0.858285414,0.592221932,1.240413709,0.588541854,DB0957010017413_,0.530107235,-0.152818584,NA,10017413,Full blood count decreased,10022891,Investigations,Inv,ixazomib,DB09570
,1884029,DB09078,10037087,14,779,38,1018,0.022190045,0.481635782,0.239290467,0.917060889,0.067055206,DB0907810037087_,2.702239028,-0.730567089,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,lenvatinib,DB09078
,1884062,DB00888,10051082,33,644,38,727,1,0.980356042,0.588231754,1.626496948,1,DB0088810051082_,0,-0.019839465,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,mechlorethamine,DB00888
,1884766,DB00169,10051082,84,38607,36,18139,0.695719425,1.096282357,0.733317921,1.668854244,0.816830399,DB0016910051082_,0.202323795,0.09192478,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,1884767,DB00186,10051082,38,16863,30,9978,0.25861216,0.749525077,0.451881095,1.253531435,0.419670319,DB0018610051082_,0.86828583,-0.288315503,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,lorazepam,DB00186
,1884770,DB00451,10051082,115,47156,33,15386,0.567023313,1.137028046,0.765880335,1.730057645,0.718223154,DB0045110051082_,0.330974958,0.128417882,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,1884771,DB00480,10051082,83,67345,88,67574,0.759706212,0.946370013,0.692482269,1.292371615,0.866253592,DB0048010051082_,0.143577582,-0.055121652,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,1884773,DB00695,10051082,112,27937,58,20470,0.03546102,1.414896424,1.020960434,1.978903764,0.096405121,DB0069510051082_,2.339195958,0.34705633,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,1884775,DB00904,10051082,34,23035,19,14437,0.77816507,1.121557351,0.621554576,2.082220271,0.879072925,DB0090410051082_,0.128887421,0.114718212,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,ondansetron,DB00904
,1884776,DB01234,10051082,56,31569,47,32841,0.280086479,1.239490716,0.825807385,1.867746557,0.443926261,DB0123410051082_,0.81209681,0.214700582,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,1886233,DB00193,10051082,35,19285,26,8676,0.053443043,0.605622989,0.354030356,1.048398725,0.131450931,DB0019310051082_,2.029121646,-0.501497617,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,1886235,DB00635,10051082,145,32908,83,23711,0.106281821,1.258740923,0.954061487,1.669972283,0.220618912,DB0063510051082_,1.511318446,0.230111954,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,1886236,DB00999,10051082,35,21395,17,12222,0.66609466,1.176083443,0.641172293,2.239646161,0.796887775,DB0099910051082_,0.227041419,0.162189802,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,1886506,DB06674,10051082,75,4431,23,1467,0.814378346,1.079583314,0.666084941,1.81239594,0.9004684,DB0667410051082_,0.104840206,0.076575146,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,golimumab,DB06674
,1887001,DB09029,10066901,53,11291,47,7223,0.122711261,0.721407869,0.477261754,1.093343842,0.24531053,DB0902910066901_,1.405230403,-0.326550603,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,1887497,DB00316,10051082,101,65373,64,36889,0.466359985,0.890516433,0.644552485,1.238122559,0.633093464,DB0031610051082_,0.457137215,-0.115953723,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,1887505,DB11581,10069339,12,1741,41,2719,0.015509059,0.457168349,0.21809456,0.889703025,0.050596453,DB1158110069339_,2.983873804,-0.782703578,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,venetoclax,DB11581
,1889399,DB00996,10051082,64,38889,43,22382,0.423764125,0.85661917,0.572830162,1.292103352,0.592543889,DB0099610051082_,0.523330335,-0.154761835,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,1889849,DB00374,10051082,224,17492,105,5619,0.001888091,0.685308469,0.540012347,0.874303472,0.009283292,DB0037410051082_,4.679539072,-0.377886223,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,treprostinil,DB00374
,1889850,DB06403,10051082,119,21352,44,6617,0.310504667,0.838123057,0.587766792,1.214441976,0.477916275,DB0640310051082_,0.738319719,-0.176590343,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,ambrisentan,DB06403
,1890062,DB05316,10016256,144,4212,176,6819,0.014314765,1.324531897,1.051620089,1.666202054,0.047439149,DB0531610016256_,3.048307469,0.281059112,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,1891699,DB09263,10000087,32,1359,35,1685,0.621427885,1.133559145,0.675568316,1.89608481,0.761715723,DB0926310000087_,0.27218186,0.125362369,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,patiromer,DB09263
,1891701,DB09263,10028813,84,1307,47,1673,5.83498100825646e-06,2.287122923,1.56929087,3.367414267,6.76245484135895e-05,DB0926310028813_,9.601539499,0.827294662,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,patiromer,DB09263
,1891766,DB11569,10022095,161,3324,76,2236,0.012166247,1.42494193,1.072105751,1.907675973,0.041609497,DB1156910022095_,3.179426841,0.354131062,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,1892530,DB09263,10016766,29,1362,41,1679,0.627674959,0.871987512,0.519653697,1.446111363,0.767039846,DB0926310016766_,0.265216529,-0.136980176,NA,10016766,Flatulence,10017947,Gastrointestinal disorders,Gastr,patiromer,DB09263
,1893206,DB09263,10000059,47,1344,49,1671,0.405856195,1.192484735,0.776568126,1.829392896,0.575404285,DB0926310000059_,0.552682382,0.176039143,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,patiromer,DB09263
,1893375,DB09263,10013968,45,1346,41,1679,0.154304868,1.368944177,0.870838211,2.157363194,0.289914471,DB0926310013968_,1.238169327,0.314039769,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,patiromer,DB09263
,1895439,DB08904,10074903,88,11522,22,3537,0.430737555,1.227891033,0.761278986,2.061427734,0.599205921,DB0890410074903_,0.512149965,0.20529809,NA,10074903,Intentional product misuse,10022117,"Injury, poisoning and procedural complications",Inj&P,certolizumab pegol,DB08904
,1898057,DB05316,10035669,12,4344,54,6941,0.000525295,0.355104364,0.172703163,0.673006798,0.003215507,DB0531610035669_,5.739770184,-1.035343549,male,10035669,Pneumonia aspiration,10021881,Infections and infestations,Infec,pimavanserin,DB05316
,1899941,DB11595,10016256,41,1072,36,998,0.817400096,1.0602645,0.65507918,1.722632157,0.902386086,DB1159510016256_,0.102712817,0.058518405,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,atezolizumab,DB11595
,1900025,DB11595,10037660,55,1058,50,984,0.920611678,1.023055104,0.677593534,1.54764021,0.964812755,DB1159510037660_,0.035821232,0.02279335,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,atezolizumab,DB11595
,1900646,DB11569,10022093,79,3406,31,2281,0.013615365,1.706505548,1.109073041,2.684971377,0.045524527,DB1156910022093_,3.089504041,0.534447741,NA,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,1900897,DB00722,10077512,40,25363,61,25971,0.057945601,0.671465267,0.438836505,1.017268063,0.139612276,DB0072210077512_,1.968886158,-0.398292989,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,lisinopril,DB00722
,1901400,DB06605,10020919,121,13952,62,12971,0.000106,1.814343397,1.323784877,2.508248243,0.000838339,DB0660510020919_,7.084088199,0.595723637,NA,10020919,Hypervolaemia,10027433,Metabolism and nutrition disorders,Metab,apixaban,DB06605
,1902054,DB06791,10000087,35,744,20,518,0.575655227,1.218234153,0.675289032,2.254069046,0.725103516,DB0679110000087_,0.321440853,0.197402395,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,lanreotide,DB06791
,1902058,DB06791,10016256,66,713,37,501,0.298810817,1.253190444,0.811118086,1.960849727,0.464789319,DB0679110016256_,0.766171053,0.225692655,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,lanreotide,DB06791
,1905375,DB00745,10036495,41,2536,19,1064,0.775584923,0.905392644,0.510941629,1.659706667,0.877771785,DB0074510036495_,0.130368646,-0.099386569,NA,10036495,Pre-existing condition improved,10018065,General disorders and administration site conditions,Genrl,modafinil,DB00745
,1905409,DB05316,10011906,602,3754,1200,5795,1.97780191499439e-06,0.774434147,0.695180894,0.862125798,2.62094899599837e-05,DB0531610011906_,10.549389,-0.255622649,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,1905618,DB00704,10042209,45,4311,40,5154,0.189711946,1.344937613,0.857054699,2.117387897,0.336136064,DB0070410042209_,1.090239248,0.296347627,NA,10042209,Stress,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,1906092,DB05316,10013573,170,4186,199,6796,0.002280277,1.386838357,1.119247728,1.716978252,0.010827659,DB0531610013573_,4.525651398,0.327026593,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,1908078,DB00051,10051082,168,25563,72,11348,0.833549025,1.035790256,0.780672799,1.386170531,0.913570529,DB0005110051082_,0.090394699,0.035164668,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,1910441,DB05316,10003549,87,4269,193,6802,0.010717079,0.718264952,0.549488667,0.932729422,0.037617471,DB0531610003549_,3.280286683,-0.330916764,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,1916340,DB08932,10051082,349,19094,142,6455,0.066835392,0.830855694,0.680222036,1.019271304,0.155635911,DB0893210051082_,1.860235901,-0.185299153,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,1920036,DB09343,10001760,57,1462,30,1853,0.00010702,2.407535619,1.512333656,3.902194365,0.000845767,DB0934310001760_,7.075266964,0.87860366,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,tipiracil,DB09343
,1920040,DB09343,10013911,28,1491,37,1846,0.899884622,0.93693919,0.549492997,1.581333415,0.956571579,DB0934310013911_,0.044399659,-0.065136898,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,tipiracil,DB09343
,1922870,DB09029,10057362,61,11283,49,7221,0.240818837,0.796740772,0.537392035,1.186586702,0.398846319,DB0902910057362_,0.919179102,-0.227225908,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,1926052,DB09302,10077812,42,2156,8,1539,0.000219255,3.746461647,1.731273348,9.264944782,0.001556968,DB0930210077812_,6.465014906,1.320811834,female,10077812,Device use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,alirocumab,DB09302
,1926209,DB11595,10047700,37,1076,18,1016,0.0205019,1.940348619,1.069029525,3.645294069,0.063020985,DB1159510047700_,2.764287515,0.662867657,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,atezolizumab,DB11595
,1926297,DB05316,10041349,173,4183,298,6697,0.46818548,0.929437803,0.763048317,1.129403234,0.634752048,DB0531610041349_,0.454520831,-0.073175389,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,1926391,DB05316,10048959,189,4167,279,6716,0.382286079,1.091794311,0.899161173,1.323503593,0.552382474,DB0531610048959_,0.593514586,0.0878225,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,1926455,DB09292,10005728,16,4513,34,8228,0.659565256,0.857989262,0.441698093,1.599407587,0.792035804,DB0929210005728_,0.233148681,-0.153163695,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,sacubitril,DB09292
,1926470,DB05316,10025482,81,4275,120,6875,0.608583487,1.085517224,0.80640734,1.454994241,0.75117358,DB0531610025482_,0.286118522,0.082056577,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,1926472,DB05316,10044565,94,4262,136,6859,0.45135188,1.112323836,0.843479736,1.461829693,0.619017722,DB0531610044565_,0.479621376,0.106451373,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,1926566,DB05316,10028813,179,4177,169,6826,5.52433779944814e-07,1.730726834,1.389664048,2.156413195,8.48173008519244e-06,DB0531610028813_,11.67759611,0.548541455,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,pimavanserin,DB05316
,1926580,DB05316,10039906,30,4326,35,6960,0.202641361,1.378963338,0.816545723,2.315733267,0.352119148,DB0531610039906_,1.043785673,0.321332012,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,1926625,DB05316,10010774,89,4267,192,6803,0.021390978,0.73905701,0.566504623,0.958076203,0.065204899,DB0531610010774_,2.730220672,-0.302380216,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,pimavanserin,DB05316
,1926628,DB05316,10037844,39,4317,74,6921,0.437269338,0.844969323,0.556985861,1.264289418,0.605708272,DB0531610037844_,0.501356808,-0.168454957,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,pimavanserin,DB05316
,1927702,DB09263,10005725,72,1319,84,1636,0.74130319,1.063099765,0.758403096,1.487169017,0.851623878,DB0926310005725_,0.160610307,0.061188947,NA,10005725,Blood potassium increased,10022891,Investigations,Inv,patiromer,DB09263
,1928343,DB11581,10035528,56,1697,103,2657,0.362874539,0.851311435,0.599970329,1.197353627,0.532396934,DB1158110035528_,0.630365952,-0.160977254,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,venetoclax,DB11581
,1928572,DB09331,10029331,67,2018,51,2378,0.024350035,1.547918119,1.053887792,2.285272103,0.072064478,DB0933110029331_,2.630194033,0.436910879,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,daratumumab,DB09331
,1929159,DB09263,10028334,30,1361,28,1692,0.288891727,1.331868942,0.764783807,2.32602882,0.453975636,DB0926310028334_,0.789711749,0.286583175,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,patiromer,DB09263
,1929555,DB09045,10033371,37,2312,21,1703,0.42214395,1.297722371,0.736947226,2.342487636,0.591215529,DB0904510033371_,0.525574643,0.260610705,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,dulaglutide,DB09045
,1930293,DB00704,10008479,29,4327,37,5157,0.805479311,0.93411673,0.553077609,1.563732336,0.894731171,DB0070410008479_,0.111231973,-0.06815387,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,1930504,DB06605,10077692,31,14042,19,13014,0.159541176,1.512104385,0.827158706,2.834445515,0.2968343,DB0660510077692_,1.214581209,0.413502313,NA,10077692,Liver function test increased,10022891,Investigations,Inv,apixaban,DB06605
,1930795,DB11362,10007815,51,6432,15,2154,0.775810297,1.13860088,0.628642902,2.184991144,0.877822795,DB1136210007815_,0.130310533,0.12980021,NA,10007815,Catheterisation cardiac,10022891,Investigations,Inv,selexipag,DB11362
,1932123,DB09263,10054112,153,1238,197,1523,0.732128937,0.955445605,0.758139956,1.202490168,0.84436879,DB0926310054112_,0.169165925,-0.045577446,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,patiromer,DB09263
,1932883,DB06643,10051082,84,52337,7,7508,0.203751478,1.721444477,0.799362521,4.41387267,0.353528788,DB0664310051082_,1.039790359,0.543163751,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,denosumab,DB06643
,1933414,DB00682,10051082,100,19359,46,16318,0.000597719,1.832390237,1.279119854,2.659677523,0.003584948,DB0068210051082_,5.631011348,0.605621255,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,warfarin,DB00682
,1933415,DB08931,10051082,87,6490,36,2410,0.609700998,0.897425233,0.600150693,1.366782546,0.75204086,DB0893110051082_,0.284964621,-0.108225468,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,riociguat,DB08931
,1936459,DB11595,10069339,27,1086,42,992,0.036972787,0.587364029,0.345439097,0.983513638,0.099523495,DB1159510069339_,2.307361529,-0.5321105,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,atezolizumab,DB11595
,1936785,DB11574,10022437,57,853,62,1011,0.70450157,1.089597834,0.737833609,1.606632585,0.822868102,DB1157410022437_,0.194959356,0.085808668,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,elbasvir,DB11574
,1937800,DB05316,10017577,166,4190,316,6679,0.076480258,0.837405588,0.686928324,1.017882627,0.172297715,DB0531610017577_,1.758531396,-0.177446752,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,1937806,DB05316,10035664,65,4291,149,6846,0.015711408,0.696015403,0.510540968,0.940033372,0.051118584,DB0531610035664_,2.973607168,-0.362383489,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,pimavanserin,DB05316
,1937834,DB05316,10046571,168,4188,143,6852,1.5455764173448e-08,1.922067266,1.523354243,2.427684659,3.32122934700217e-07,DB0531610046571_,14.91776065,0.653401308,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,pimavanserin,DB05316
,1937851,DB05316,10061920,44,4312,94,6901,0.134057728,0.74915003,0.51028112,1.085060618,0.26141232,DB0531610061920_,1.341656347,-0.288816008,NA,10061920,Psychotic disorder,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,1938189,DB00704,10027175,28,4328,37,5157,0.709422807,0.901742578,0.53061781,1.516686459,0.82659597,DB0070410027175_,0.190439253,-0.103426189,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,naltrexone,DB00704
,1938427,DB00704,10013781,33,4323,24,5170,0.082046286,1.644294887,0.941180322,2.912326798,0.181783337,DB0070410013781_,1.704939757,0.497311652,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,naltrexone,DB00704
,1940193,DB09564,10013709,38,1189,30,917,1,0.976902478,0.584398079,1.646295944,1,DB0956410013709_,0,-0.02336845,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,insulin degludec,DB09564
,1940230,DB06605,10003481,31,14042,31,13002,0.799911202,0.925957354,0.544063404,1.575934398,0.891818188,DB0660510003481_,0.114492992,-0.0769271,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,apixaban,DB06605
,1940909,DB11362,10018964,45,6438,26,2143,0.027905139,0.576158401,0.346937207,0.975319995,0.080018173,DB1136210018964_,2.525501513,-0.551372655,NA,10018964,Haemoptysis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,1942676,DB09292,10028997,18,4511,41,8221,0.496111221,0.800079317,0.432113145,1.426150809,0.658433903,DB0929210028997_,0.417891137,-0.22304441,NA,10028997,Neoplasm malignant,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,sacubitril,DB09292
,1943524,DB09263,10025482,52,1339,52,1668,0.271931491,1.245610628,0.825651848,1.879265387,0.43477611,DB0926310025482_,0.83292407,0.219625874,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,patiromer,DB09263
,1944237,DB00181,10051082,63,9793,60,5811,0.011192675,0.623098616,0.429828704,0.904023427,0.038951339,DB0018110051082_,3.245442131,-0.47305048,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,1944242,DB00678,10051082,47,15552,21,10703,0.108480577,1.540247684,0.902174929,2.714270924,0.223763004,DB0067810051082_,1.497167803,0.431943237,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,1944244,DB01076,10051082,71,25676,48,25535,0.043153186,1.471025663,1.005273087,2.169035357,0.111978033,DB0107610051082_,2.189452557,0.385959887,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,1947263,DB06791,10000081,43,736,23,515,0.368706549,1.307926649,0.760098619,2.303662004,0.538354163,DB0679110000081_,0.61923864,0.268443172,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,lanreotide,DB06791
,1947613,DB11595,10053762,38,1075,27,1007,0.313954355,1.318209182,0.777498774,2.262971033,0.481498902,DB1159510053762_,0.730851329,0.276274135,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,atezolizumab,DB11595
,1948611,DB05316,10021097,23,4333,50,6945,0.277045244,0.737314304,0.428747516,1.233010589,0.440553812,DB0531610021097_,0.819722679,-0.304741014,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,pimavanserin,DB05316
,1948618,DB05316,10045555,29,4327,46,6949,1,1.012456908,0.612336414,1.649085826,1,DB0531610045555_,0,0.012379959,NA,10045555,Unresponsive to stimuli,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,1949961,DB05990,10037087,549,810,53,114,0.035714827,1.457511666,1.023343645,2.097072365,0.096909695,DB0599010037087_,2.33397571,0.376730643,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,obeticholic acid,DB05990
,1950396,DB11581,10045170,22,1731,59,2701,0.029146662,0.581898486,0.338188051,0.968144011,0.082823786,DB1158110045170_,2.491039989,-0.541459269,NA,10045170,Tumour lysis syndrome,10027433,Metabolism and nutrition disorders,Metab,venetoclax,DB11581
,1950401,DB11581,10061818,37,1716,67,2693,0.541891713,0.866652705,0.561167453,1.320411608,0.697208629,DB1158110061818_,0.360670589,-0.143116954,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,venetoclax,DB11581
,1951288,DB11362,10023232,76,6407,24,2145,0.907678156,1.060149147,0.660398505,1.759461504,0.958771936,DB1136210023232_,0.042102046,0.058409603,NA,10023232,Joint swelling,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1951293,DB11362,10038428,70,6413,26,2143,0.636709148,0.899674482,0.564495362,1.47470677,0.774218766,DB1136210038428_,0.255900802,-0.105722267,NA,10038428,Renal disorder,10038359,Renal and urinary disorders,Renal,selexipag,DB11362
,1951296,DB00381,10051082,96,29264,58,22829,0.142974478,1.291201343,0.922009217,1.821948907,0.274012698,DB0038110051082_,1.294580829,0.255573059,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,1951428,DB05316,10016322,88,4268,139,6856,0.945056489,1.016989025,0.76747277,1.341637648,0.983677576,DB0531610016322_,0.016457103,0.016846325,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,1951593,DB00264,10051082,56,29551,48,24844,0.921895075,0.980831584,0.654842811,1.47411089,0.965493374,DB0026410051082_,0.03511604,-0.019354512,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,1951594,DB00404,10051082,36,19856,14,9848,0.54779563,1.275297664,0.670900658,2.561068322,0.702363754,DB0040410051082_,0.353303841,0.243179614,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,1952132,DB08895,10048865,66,28048,30,6616,0.004023489,0.51897734,0.331928423,0.828567448,0.01716423,DB0889510048865_,4.064927723,-0.655895058,NA,10048865,Hypoacusis,10013993,Ear and labyrinth disorders,Ear,tofacitinib,DB08895
,1957713,DB11362,10061224,40,6443,23,2146,0.040996785,0.579301911,0.337627465,1.016100998,0.107652994,DB1136210061224_,2.228842241,-0.545931503,NA,10061224,Limb discomfort,10028395,Musculoskeletal and connective tissue disorders,Musc,selexipag,DB11362
,1961921,DB05316,10001497,61,4295,181,6814,1.69057283767554e-05,0.534703647,0.392258041,0.720405461,0.000172169,DB0531610001497_,8.667036523,-0.626042616,NA,10001497,Agitation,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,1961922,DB05316,10061422,120,4236,287,6708,0.000147013,0.66214293,0.528651871,0.82521344,0.001107389,DB0531610061422_,6.805750237,-0.41227384,NA,10061422,Abnormal behaviour,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,1962228,DB00203,10051082,184,13694,95,8843,0.08394508,1.250701867,0.969669748,1.621989733,0.18498461,DB0020310051082_,1.687482645,0.223704888,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,1962229,DB00421,10051082,51,8852,18,5234,0.061218727,1.675232409,0.961013516,3.050424046,0.145675742,DB0042110051082_,1.926372072,0.515951907,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,spironolactone,DB00421
,1962326,DB00073,10051082,44,7362,23,6384,0.049819927,1.658842523,0.97901482,2.881375073,0.12469807,DB0007310051082_,2.081859907,0.506120084,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,1962817,DB00704,10011469,35,4321,16,5178,0.001052326,2.621106247,1.410733097,5.078577659,0.005748809,DB0070410011469_,5.158762523,0.96359646,NA,10011469,Crying,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,1963874,DB00704,10022052,59,4297,40,5154,0.00594683,1.769046491,1.161742874,2.718713649,0.023498561,DB0070410022052_,3.750816106,0.570440696,NA,10022052,Injection site bruising,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,1964812,DB11362,10013578,36,6447,18,2151,0.158875171,0.667321545,0.368266478,1.251035998,0.295994178,DB1136210013578_,1.217415493,-0.404483273,NA,10013578,Dizziness postural,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1964822,DB11362,10027175,88,6395,21,2148,0.182073859,1.407448191,0.864102503,2.392212218,0.32647598,DB1136210027175_,1.119398902,0.341778271,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1964826,DB11362,10029331,36,6447,18,2151,0.158875171,0.667321545,0.368266478,1.251035998,0.295994178,DB1136210029331_,1.217415493,-0.404483273,NA,10029331,Neuropathy peripheral,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,1965344,DB09302,10069868,80,2118,38,1509,0.045812555,1.499767963,1.000941392,2.282073676,0.117112807,DB0930210069868_,2.144617647,0.405310405,NA,10069868,Device issue,10077536,Product issues,Prod,alirocumab,DB09302
,1965496,DB05316,10001488,84,4272,222,6773,6.10686536703941e-05,0.599922291,0.459654877,0.776930683,0.000523621,DB0531610001488_,7.554741982,-0.510955148,NA,10001488,Aggression,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,1965497,DB05316,10002368,25,4331,56,6939,0.170731761,0.715274998,0.426977945,1.167447783,0.311839645,DB0531610002368_,1.165266181,-0.335088198,NA,10002368,Anger,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,1965504,DB05316,10061822,30,4326,40,6955,0.460620467,1.205760033,0.724051936,1.988320963,0.627974638,DB0531610061822_,0.465255498,0.187110101,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,1969102,DB05316,10012267,66,4290,139,6856,0.070043451,0.758847471,0.555898637,1.027078763,0.161342751,DB0531610012267_,1.824224288,-0.275954483,NA,10012267,Dementia,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,1970574,DB00904,10077834,31,23038,30,14426,0.088718517,0.647085432,0.378681627,1.107022796,0.19312836,DB0090410077834_,1.644400234,-0.43527695,NA,10077834,Left-to-right cardiac shunt,10010331,"Congenital, familial and genetic disorders",Cong,ondansetron,DB00904
,1973967,DB00338,10051082,84,33590,45,22227,0.28017098,1.235178358,0.849695989,1.816598632,0.444006645,DB0033810051082_,0.811915751,0.211215379,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,1974355,DB05316,10024855,28,4328,42,6953,0.805784397,1.071003245,0.638327347,1.771962394,0.894899878,DB0531610024855_,0.111043435,0.068595822,NA,10024855,Loss of consciousness,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,1975091,DB00331,10051082,56,24890,31,20721,0.067825718,1.503859914,0.952654704,2.414170588,0.157414595,DB0033110051082_,1.848872223,0.408035079,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,1975095,DB06605,10051082,63,14010,36,12997,0.020389368,1.62343008,1.060518245,2.519325484,0.062749304,DB0660510051082_,2.7686078,0.484541244,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,apixaban,DB06605
,1975413,DB11362,10049438,57,6426,22,2147,0.601823818,0.865687636,0.519526995,1.490880785,0.746035609,DB1136210049438_,0.292981947,-0.144231133,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,1979147,DB08895,10011376,48,28066,14,6632,0.516985602,0.810177348,0.439023038,1.592202857,0.676623425,DB0889510011376_,0.390640402,-0.210502107,NA,10011376,Crepitations,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,1981825,DB11595,10035664,43,1070,43,991,0.742264074,0.926217611,0.587014721,1.461427569,0.852280761,DB1159510035664_,0.159839275,-0.076646071,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,atezolizumab,DB11595
,1982771,DB11569,10010264,81,3404,48,2264,0.585631775,1.122363766,0.772561588,1.645856031,0.733044896,DB1156910010264_,0.31054833,0.115436967,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,1983667,DB11362,10018627,34,6449,16,2153,0.254491688,0.709462348,0.380164884,1.37938316,0.415188779,DB1136210018627_,0.879021972,-0.343247852,NA,10018627,Gout,10027433,Metabolism and nutrition disorders,Metab,selexipag,DB11362
,1983681,DB00688,10051082,29,6461,30,5348,0.432406312,0.800163207,0.462768407,1.381622334,0.600812189,DB0068810051082_,0.50947289,-0.222939564,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,mycophenolate mofetil,DB00688
,1984377,DB00559,10051082,64,9595,18,3288,0.526067619,1.218387796,0.711883546,2.187985988,0.683987931,DB0055910051082_,0.379815006,0.197528506,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,bosentan,DB00559
,1984378,DB00641,10051082,32,14092,24,12451,0.593192376,1.178059976,0.672018928,2.091406093,0.739293122,DB0064110051082_,0.302060789,0.163868998,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,1984380,DB01240,10051082,67,5684,27,1549,0.099602191,0.676292224,0.424986774,1.104014216,0.210170636,DB0124010051082_,1.559835527,-0.391130012,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,1986089,DB05990,10016256,151,1208,17,150,0.79423469,1.102858075,0.643675411,1.998869863,0.888516684,DB0599010016256_,0.118201854,0.09790506,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,obeticholic acid,DB05990
,1986324,DB01073,10051398,55,1010,82,1568,0.857598662,1.041311376,0.719253933,1.497874855,0.931775585,DB0107310051398_,0.070663282,0.040480857,NA,10051398,Malignant neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fludarabine,DB01073
,1987456,DB00541,10061309,36,3098,48,4249,0.911878508,1.028656106,0.646935818,1.622606604,0.960554907,DB0054110061309_,0.040244134,0.028253199,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,vincristine,DB00541
,1987458,DB00987,10061309,29,2075,40,2888,1,1.00905978,0.6011834,1.674992288,1,DB0098710061309_,0,0.009018987,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,cytarabine,DB00987
,1991847,DB00211,10054112,28,1408,39,1592,0.458259977,0.811827195,0.478400657,1.361387927,0.62561942,DB0021110054112_,0.469013048,-0.208467775,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,midodrine,DB00211
,1993707,DB14185,10013709,28,536,40,593,0.320456585,0.774605742,0.453413389,1.307365181,0.488627278,DB1418510013709_,0.716155293,-0.255401099,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,aripiprazole lauroxil,DB14185
,1994770,DB11362,10020772,66,6417,28,2141,0.283229666,0.786471016,0.496878581,1.274845937,0.447578596,DB1136210020772_,0.803903123,-0.240199409,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,selexipag,DB11362
,1994957,DB05316,10047700,58,4298,47,6948,0.000544244,1.994826114,1.331664939,3.002002817,0.003310299,DB0531610047700_,5.710716777,0.690556886,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,pimavanserin,DB05316
,1997312,DB00005,10078504,219,127863,45,42374,0.002702009,1.612762635,1.165511546,2.275809303,0.012412147,DB0000510078504_,4.389079712,0.477948631,NA,10078504,Contraindicated product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,1997313,DB00563,10078504,311,46335,68,15280,0.001858504,1.508174846,1.156044944,1.992112987,0.009159233,DB0056310078504_,4.692992854,0.410900209,NA,10078504,Contraindicated product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,1997314,DB01611,10078504,73,11840,15,2346,0.885580737,0.964288444,0.546978577,1.813473004,0.952411128,DB0161110078504_,0.04875848,-0.036364813,NA,10078504,Contraindicated product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxychloroquine,DB01611
,1997315,DB08895,10078504,110,28004,20,6626,0.31523585,1.301337472,0.802475405,2.214963881,0.482823431,DB0889510078504_,0.72810426,0.263392561,NA,10078504,Contraindicated product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,1997327,DB05316,10002855,104,4252,97,6898,0.000129637,1.739210732,1.302506936,2.324343836,0.000995183,DB0531610002855_,6.91258346,0.553431408,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,1997331,DB05316,10048334,23,4333,48,6947,0.328944955,0.768262977,0.445340337,1.290151832,0.497555081,DB0531610048334_,0.698049013,-0.263623187,NA,10048334,Mobility decreased,10028395,Musculoskeletal and connective tissue disorders,Musc,pimavanserin,DB05316
,1997367,DB05316,10000059,48,4308,41,6954,0.003005638,1.889741471,1.217243515,2.945540401,0.013532577,DB0531610000059_,4.302655372,0.636440032,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,pimavanserin,DB05316
,1997394,DB05316,10020765,45,4311,100,6895,0.071216161,0.719748738,0.493545021,1.03542263,0.163401811,DB0531610020765_,1.811543012,-0.328853103,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,1997897,DB09078,10015090,16,777,40,1016,0.028554662,0.523213691,0.27140519,0.963806248,0.081511652,DB0907810015090_,2.507009299,-0.647765312,NA,10015090,Epistaxis,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenvatinib,DB09078
,1998525,DB11581,10025197,12,1741,38,2722,0.039932254,0.493798004,0.23424119,0.968546647,0.105537107,DB1158110025197_,2.248692666,-0.705628745,NA,10025197,Lymphadenopathy,10005329,Blood and lymphatic system disorders,Blood,venetoclax,DB11581
,2002236,DB11362,10006784,37,6446,16,2153,0.426178445,0.772412505,0.418248692,1.490361827,0.594833505,DB1136210006784_,0.519473736,-0.258236539,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,2002877,DB09029,10051082,89,11255,56,7214,0.932163534,1.018667659,0.720104357,1.451558978,0.972993348,DB0902910051082_,0.027378034,0.018495557,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,2004912,DB11362,10047924,56,6427,17,2152,0.78763114,1.10298071,0.6299499,2.029444297,0.884946654,DB1136210047924_,0.122227913,0.098016251,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,selexipag,DB11362
,2007206,DB09029,10054112,45,11299,26,7244,0.716020094,1.109642913,0.669344822,1.875287955,0.831977905,DB0902910054112_,0.183949395,0.104038263,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,secukinumab,DB09029
,2007779,DB11569,10022107,44,3441,9,2303,0.000573725,3.271470541,1.572308518,7.637397379,0.003461277,DB1156910022107_,5.666117643,1.185239591,female,10022107,Injection site urticaria,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,2011468,DB08895,10072850,123,27991,30,6616,0.837320079,0.969080953,0.645176844,1.49817678,0.916179808,DB0889510072850_,0.087542637,-0.031407128,NA,10072850,Sensitivity to weather change,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,2011901,DB05316,10054112,94,4262,178,6817,0.206918247,0.844710201,0.648795874,1.093921875,0.35754831,DB0531610054112_,1.028484792,-0.168761668,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,pimavanserin,DB05316
,2012165,DB01373,10051082,40,22680,20,7361,0.13176575,0.649128795,0.370371409,1.172810137,0.258264996,DB0137310051082_,1.353769106,-0.432124131,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,2012429,DB11595,10028813,40,1073,15,1019,0.001581002,2.531620103,1.358266636,4.964885074,0.008019422,DB1159510028813_,4.825888967,0.928859455,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,atezolizumab,DB11595
,2015502,DB01281,10051082,65,8867,11,1787,0.757430975,1.190862515,0.622051497,2.507567935,0.86438411,DB0128110051082_,0.145738037,0.174677847,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,abatacept,DB01281
,2015574,DB11569,10001760,50,3435,11,2301,0.000322788,3.044340233,1.560207153,6.498866544,0.002142008,DB1156910001760_,6.146011578,1.113284206,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,ixekizumab,DB11569
,2015729,DB11569,10021789,59,3426,50,2262,0.20060224,0.779133594,0.523340047,1.163880873,0.349747871,DB1156910021789_,1.050542752,-0.249572754,NA,10021789,Infection,10021881,Infections and infestations,Infec,ixekizumab,DB11569
,2015754,DB00635,10061309,43,33010,30,23764,1,1.031863487,0.632280652,1.704133045,1,DB0063510061309_,0,0.031366378,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,prednisone,DB00635
,2015929,DB01098,10051082,30,8119,25,7184,0.892682633,1.061820238,0.603011343,1.884778613,0.9552998,DB0109810051082_,0.045730061,0.059984641,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,rosuvastatin,DB01098
,2016121,DB09078,10011224,22,771,33,1023,0.681140719,0.884646647,0.487128647,1.577732681,0.807185762,DB0907810011224_,0.214201449,-0.122566983,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenvatinib,DB09078
,2016573,DB00497,10010121,37,19230,16,16359,0.026466478,1.967178302,1.06726968,3.789337995,0.076789159,DB0049710010121_,2.566691807,0.676600182,NA,10010121,Compartment syndrome,10028395,Musculoskeletal and connective tissue disorders,Musc,oxycodone,DB00497
,2016678,DB00761,10051082,52,15255,20,8605,0.175867246,1.466578752,0.859998718,2.59530518,0.318475409,DB0076110051082_,1.144210015,0.382932309,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,potassium chloride,DB00761
,2018628,DB11581,10008958,27,1726,48,2712,0.635098097,0.88383683,0.528135885,1.451486682,0.773227836,DB1158110008958_,0.257181531,-0.123482815,NA,10008958,Chronic lymphocytic leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,venetoclax,DB11581
,2021940,DB11362,10040047,97,6386,42,2127,0.167162447,0.769263384,0.528439318,1.13672521,0.307048562,DB1136210040047_,1.180749363,-0.262321866,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,selexipag,DB11362
,2023078,DB09331,10043607,31,2054,23,2406,0.10100481,1.578628817,0.887930921,2.844902192,0.21231648,DB0933110043607_,1.549677286,0.456556633,NA,10043607,Thrombosis,10047065,Vascular disorders,Vasc,daratumumab,DB09331
,2026235,DB01281,10017076,266,8666,50,1748,0.702539398,1.073108443,0.786947184,1.488864813,0.821576595,DB0128110017076_,0.196530108,0.070559524,NA,10017076,Fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,abatacept,DB01281
,2026557,DB05316,10021021,14,4342,40,6955,0.067892293,0.560655798,0.281398831,1.054133712,0.157532666,DB0531610021021_,1.848122438,-0.578648113,NA,10021021,Hypokinesia,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,2026664,DB05316,10040984,13,4343,48,6947,0.005374281,0.433250396,0.215093703,0.813593272,0.021669425,DB0531610040984_,3.83185298,-0.836439437,NA,10040984,Sleep disorder,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,2026665,DB05316,10061623,103,4253,166,6829,1,0.996301983,0.769077588,1.285687409,1,DB0531610061623_,0,-0.003704871,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,2026666,DB05316,10028372,41,4315,74,6921,0.564841011,0.888659265,0.590282934,1.321592498,0.716495559,DB0531610028372_,0.33338323,-0.118041396,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,pimavanserin,DB05316
,2026671,DB05316,10013395,35,4321,87,6908,0.030932383,0.643180749,0.420695462,0.964392503,0.086781694,DB0531610013395_,2.444359579,-0.441329491,NA,10013395,Disorientation,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,2026718,DB05316,10013916,23,4333,32,6963,0.677016096,1.15498931,0.644444723,2.039570699,0.804128697,DB0531610013916_,0.217995951,0.144091089,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,2026725,DB05316,10027175,44,4312,85,6910,0.362614482,0.829569381,0.561714524,1.2101619,0.53220767,DB0531610027175_,0.630721509,-0.186848531,NA,10027175,Memory impairment,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,2028670,DB09078,10011906,43,750,89,967,0.013642927,0.623091406,0.417144024,0.918887419,0.045606556,DB0907810011906_,3.087703806,-0.473062051,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,lenvatinib,DB09078
,2032191,DB11362,10038063,50,6433,9,2160,0.096438252,1.865372086,0.906163018,4.321676084,0.205410123,DB1136210038063_,1.582746697,0.623460543,NA,10038063,Rectal haemorrhage,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,2033007,DB11362,10053762,43,6440,16,2153,0.763005411,0.898475677,0.49467644,1.71253777,0.86873333,DB1136210053762_,0.140719071,-0.107055644,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,selexipag,DB11362
,2033909,DB01234,10033733,30,31595,23,32865,0.275462122,1.356765444,0.761833021,2.446360146,0.438766325,DB0123410033733_,0.823788298,0.305103517,NA,10033733,Papule,10040785,Skin and subcutaneous tissue disorders,Skin,dexamethasone,DB01234
,2038641,DB11595,10011906,101,1012,94,940,1,0.998024594,0.735283169,1.355633092,1,DB1159510011906_,0,-0.00197736,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,atezolizumab,DB11595
,2039187,DB11569,10013968,36,3449,17,2295,0.262638065,1.409023239,0.769088209,2.682057206,0.42440841,DB1156910013968_,0.857059056,0.342896726,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ixekizumab,DB11569
,2041782,DB08895,10051082,149,27965,46,6600,0.120141845,0.764471678,0.545275657,1.089782733,0.241563279,DB0889510051082_,1.420623817,-0.268570301,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,2042043,DB01611,10051082,64,11849,10,2351,0.637115025,1.269824707,0.64641753,2.778133523,0.774461508,DB0161110051082_,0.255587319,0.238878865,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,hydroxychloroquine,DB01611
,2042785,DB05316,10005750,37,4319,63,6932,0.836655944,0.942618595,0.609386917,1.439641873,0.915625842,DB0531610005750_,0.088147467,-0.059093538,NA,10005750,Blood pressure increased,10022891,Investigations,Inv,pimavanserin,DB05316
,2050323,DB05316,10008190,34,4322,34,6961,0.059869282,1.610466579,0.969688807,2.674907463,0.143249198,DB0531610008190_,1.94316952,0.476523937,NA,10008190,Cerebrovascular accident,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,2050324,DB05316,10057668,31,4325,55,6940,0.738706047,0.904417808,0.561866537,1.432289687,0.849642867,DB0531610057668_,0.162939174,-0.100463848,NA,10057668,Cognitive disorder,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,2051408,DB05316,10033864,53,4303,82,6913,0.858835121,1.038408896,0.719224452,1.488070511,0.932926176,DB0531610033864_,0.069429207,0.037689634,NA,10033864,Paranoia,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,2051411,DB05316,10030124,90,4266,94,6901,0.003604565,1.548719863,1.143909759,2.095880541,0.015687721,DB0531610030124_,4.154876959,0.437428695,NA,10030124,Oedema peripheral,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,2051448,DB05316,10000125,40,4316,57,6938,0.600394999,1.128059586,0.732174123,1.72329593,0.744826437,DB0531610000125_,0.294604058,0.120498976,NA,10000125,Abnormal dreams,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,2053725,DB05316,10047895,42,4314,69,6926,1,0.977243875,0.648269261,1.457782342,1,DB0531610047895_,0,-0.023019042,NA,10047895,Weight decreased,10022891,Investigations,Inv,pimavanserin,DB05316
,2054882,DB00316,10013954,69,65405,14,36939,0.000206092,2.783492576,1.551849414,5.35690881,0.001477265,DB0031610013954_,6.517563061,1.023706461,female,10013954,Dysphoria,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,2055506,DB11362,10017367,39,6444,14,2155,0.873659455,0.931598596,0.493685018,1.86118309,0.945065179,DB1136210017367_,0.056501382,-0.070853248,NA,10017367,Frequent bowel movements,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,2056750,DB05316,10019211,70,4286,57,6938,0.00014768,1.987866035,1.378093998,2.877650438,0.001111427,DB0531610019211_,6.802110833,0.687061719,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,2056758,DB05316,10052904,25,4331,41,6954,1,0.979045943,0.569666604,1.651564723,1,DB0531610052904_,0,-0.021176709,NA,10052904,Musculoskeletal stiffness,10028395,Musculoskeletal and connective tissue disorders,Musc,pimavanserin,DB05316
,2059271,DB09263,10035664,39,1352,33,1687,0.118780967,1.474445304,0.898190568,2.433641521,0.239392556,DB0926310035664_,1.429650581,0.388281854,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,patiromer,DB09263
,2061902,DB05316,10008479,39,4317,39,6956,0.035941454,1.611173515,1.00504344,2.583099707,0.09741852,DB0531610008479_,2.328738943,0.476962805,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,2066125,DB11569,10053762,45,3440,20,2292,0.160738373,1.499027198,0.864548034,2.687287659,0.298534402,DB1156910053762_,1.208870104,0.404816363,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,ixekizumab,DB11569
,2066178,DB00722,10051082,45,25358,42,25990,0.669519137,1.098119376,0.704715853,1.714363929,0.799378086,DB0072210051082_,0.223921247,0.093599059,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,2066810,DB00016,10051082,24,2738,31,2259,0.103677311,0.638817379,0.35764213,1.128169565,0.216514371,DB0001610051082_,1.530098356,-0.448136658,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,erythropoietin,DB00016
,2066811,DB00115,10051082,38,18387,22,10450,1,0.981663955,0.565623518,1.743474522,1,DB0011510051082_,0,-0.018506234,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,2066832,DB11362,10013709,77,6406,36,2133,0.101151158,0.712214253,0.471956112,1.092889753,0.212547621,DB1136210013709_,1.548589215,-0.339376495,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,2066835,DB11362,10074300,138,6345,40,2129,0.48443734,1.157590186,0.805805153,1.695869531,0.648622646,DB1136210074300_,0.432904171,0.146340418,NA,10074300,Therapy change,10042613,Surgical and medical procedures,Surg,selexipag,DB11362
,2073624,DB00213,10051082,46,18849,24,13397,0.227434254,1.362264622,0.814037105,2.33464448,0.382647978,DB0021310051082_,0.960639831,0.309148478,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,2076352,DB05316,10041466,41,4315,64,6931,0.919804759,1.029023523,0.676418,1.549778466,0.964515682,DB0531610041466_,0.036129187,0.028610317,NA,10041466,Speech disorder,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,2076499,DB05316,10061428,51,4305,87,6908,0.791798866,0.940652963,0.650894193,1.347223699,0.887296777,DB0531610061428_,0.119575767,-0.061181004,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,pimavanserin,DB05316
,2080354,DB09140,10051082,60,3681,28,1770,1,1.030414399,0.645058566,1.682641924,1,DB0914010051082_,0,0.02996105,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,oxygen,DB09140
,2080619,DB11569,10012735,97,3388,64,2248,1,1.005644035,0.722446415,1.407887626,1,DB1156910012735_,0,0.005628167,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ixekizumab,DB11569
,2080620,DB11569,10046571,61,3424,6,2306,2.00330308551861e-08,6.844174315,2.963538201,19.40938712,4.19242210213827e-07,DB1156910046571_,14.68481702,1.923397825,female,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ixekizumab,DB11569
,2087220,DB01611,10022523,45,11868,9,2352,1,0.990900191,0.477502029,2.308742719,1,DB0161110022523_,0,-0.009141465,NA,10022523,Intentional overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxychloroquine,DB01611
,2088001,DB00343,10051082,51,8685,26,5069,0.636418508,1.144865377,0.699609219,1.915452939,0.773999962,DB0034310051082_,0.256183454,0.135287055,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,diltiazem,DB00343
,2096642,DB09029,10047461,34,11310,16,7254,0.383967084,1.362908959,0.731391402,2.646385665,0.553989175,DB0902910047461_,0.590610132,0.309621356,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,secukinumab,DB09029
,2100086,DB11569,10022094,47,3438,27,2285,0.633032357,1.156882312,0.703607313,1.93783852,0.771750551,DB1156910022094_,0.259093901,0.145728724,NA,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,2102793,DB11569,10013709,187,3298,138,2174,0.350931893,0.893266138,0.70811726,1.128915856,0.520647938,DB1156910013709_,0.652681209,-0.112870716,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,2103953,DB00007,10069218,17,1930,483,3969,3.35301347822573e-57,0.072395698,0.041676193,0.117585452,2.63086445597502e-54,DB0000710069218_,123.3722825,-2.6256084,male,10069218,Syringe issue,10077536,Product issues,Prod,leuprolide,DB00007
,2117513,DB00704,10028810,50,4306,40,5154,0.070119095,1.496087858,0.965384199,2.331966708,0.161447129,DB0070410028810_,1.823577566,0.402853606,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,naltrexone,DB00704
,2124137,DB05316,10020100,48,4308,45,6950,0.009967658,1.720676767,1.119534155,2.649104116,0.035474904,DB0531610020100_,3.338929773,0.542717683,NA,10020100,Hip fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,pimavanserin,DB05316
,2124145,DB05316,10033371,41,4315,28,6967,0.000439775,2.364068919,1.424702039,3.975944189,0.002775051,DB0531610033371_,5.88708624,0.860384253,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,2125291,DB01611,10017076,72,11841,11,2350,0.552470554,1.299006946,0.683138978,2.721887014,0.706341183,DB0161110017076_,0.347656896,0.261600085,NA,10017076,Fracture,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxychloroquine,DB01611
,2134405,DB09564,10016256,32,1195,23,924,0.890648685,1.075770756,0.605472187,1.939356349,0.954671384,DB0956410016256_,0.046388098,0.073037387,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,insulin degludec,DB09564
,2135241,DB00959,10076308,72,8006,28,4974,0.038454381,1.597532744,1.017735905,2.571931841,0.102543714,DB0095910076308_,2.277466089,0.468460404,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,methylprednisolone,DB00959
,2138071,DB09263,10013709,20,1371,37,1683,0.178324358,0.663638149,0.363164324,1.17968198,0.321772207,DB0926310013709_,1.133911415,-0.410018235,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,patiromer,DB09263
,2138288,DB09263,10067482,43,1348,37,1683,0.110847541,1.450785046,0.90722581,2.330208454,0.227351849,DB0926310067482_,1.481256466,0.372104821,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,patiromer,DB09263
,2151837,DB00904,10047298,35,23034,30,14426,0.205106158,0.730696439,0.435615451,1.232620216,0.355269546,DB0090410047298_,1.034878494,-0.313757173,NA,10047298,Ventricular septal defect,10010331,"Congenital, familial and genetic disorders",Cong,ondansetron,DB00904
,2153925,DB14185,10019070,35,529,47,586,0.424321567,0.825053419,0.508454442,1.328118907,0.593157248,DB1418510019070_,0.522295741,-0.192307144,NA,10019070,"Hallucination, auditory",10037175,Psychiatric disorders,Psych,aripiprazole lauroxil,DB14185
,2158789,DB05316,10050256,32,4324,90,6905,0.004958001,0.56781397,0.366245248,0.86033385,0.0203309,DB0531610050256_,3.895613399,-0.565961431,NA,10050256,Dysstasia,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,2158848,DB05316,10061818,18,4338,49,6946,0.058444264,0.588221589,0.322046104,1.02953669,0.14058822,DB0531610061818_,1.96192009,-0.53065155,NA,10061818,Disease progression,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,2160209,DB11362,10067671,39,6444,16,2153,0.532125746,0.814395257,0.443660373,1.564414719,0.688977156,DB1136210067671_,0.372547164,-0.205309457,NA,10067671,Disease complication,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,2160923,DB00678,10061309,41,15558,13,10711,0.012371353,2.171214273,1.139914208,4.418440145,0.042171057,DB0067810061309_,3.166021158,0.775286584,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,losartan,DB00678
,2162321,DB06643,10073311,199,52222,21,7494,0.219928478,1.359852512,0.864915675,2.247166908,0.373341516,DB0664310073311_,0.985261685,0.307376247,NA,10073311,Occupational exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,2166033,DB05316,10067889,23,4333,30,6965,0.480278453,1.23232751,0.682651922,2.197316694,0.645091553,DB0531610067889_,0.43836303,0.208904666,NA,10067889,Dementia with Lewy bodies,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,2166042,DB11611,10013911,192,1534,20,363,0.000324117,2.271121098,1.40594332,3.855549125,0.002149624,DB1161110013911_,6.142462215,0.820273585,NA,10013911,Dysgeusia,10029205,Nervous system disorders,Nerv,lifitegrast,DB11611
,2166043,DB11611,10030041,72,1654,15,368,0.888015364,1.067889577,0.598141101,2.029501723,0.953608851,DB1161110030041_,0.047501701,0.065684343,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,lifitegrast,DB11611
,2166099,DB11611,10010264,51,1675,8,375,0.492066749,1.427015042,0.664889603,3.511652098,0.65501299,DB1161110010264_,0.423100211,0.35558488,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,lifitegrast,DB11611
,2166184,DB11611,10047513,340,1386,92,291,0.059186538,0.776024861,0.593177814,1.021228451,0.141965073,DB1161110047513_,1.952174215,-0.253570722,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,lifitegrast,DB11611
,2166186,DB11611,10047571,69,1657,11,372,0.374598496,1.408025604,0.730835651,2.980844208,0.544492022,DB1161110047571_,0.607901989,0.342188442,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,lifitegrast,DB11611
,2166188,DB11611,10055117,78,1648,10,373,0.118652547,1.764981607,0.899268244,3.861878149,0.239188757,DB1161110055117_,1.430502262,0.568140269,NA,10055117,Instillation site irritation,10018065,General disorders and administration site conditions,Genrl,lifitegrast,DB11611
,2167141,DB11569,10011906,35,3450,23,2289,1,1.009639399,0.578203362,1.794688603,1,DB1156910011906_,0,0.009593237,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,2167580,DB11611,10015915,46,1680,6,377,0.273944534,1.720043379,0.725452762,4.964894428,0.437024373,DB1161110015915_,0.827766312,0.542349511,NA,10015915,Eye discharge,10015919,Eye disorders,Eye,lifitegrast,DB11611
,2167593,DB11611,10069327,77,1649,28,355,0.026591085,0.592195991,0.373284306,0.963009907,0.077069871,DB1161110069327_,2.563042856,-0.523917632,NA,10069327,Product quality issue,10077536,Product issues,Prod,lifitegrast,DB11611
,2167999,DB11581,10016256,69,1684,79,2681,0.058858342,1.390379646,0.985854363,1.957178959,0.141325617,DB1158110016256_,1.956688711,0.329576837,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,venetoclax,DB11581
,2169937,DB11611,10022459,396,1330,57,326,0.0004355,1.702500152,1.250962602,2.34854346,0.002751708,DB1161110022459_,5.895533332,0.532097848,NA,10022459,Instillation site pain,10018065,General disorders and administration site conditions,Genrl,lifitegrast,DB11611
,2170618,DB05990,10065154,86,1273,10,157,1,1.060615425,0.535090012,2.338709074,1,DB0599010065154_,0,0.058849329,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,obeticholic acid,DB05990
,2170976,DB11611,10063765,295,1431,65,318,1,1.008544624,0.746548602,1.376795871,1,DB1161110063765_,0,0.008508325,NA,10063765,Instillation site reaction,10018065,General disorders and administration site conditions,Genrl,lifitegrast,DB11611
,2172123,DB11611,10015946,182,1544,41,342,0.926876014,0.983262623,0.681932149,1.444583463,0.969109808,DB1161110015946_,0.031377353,-0.01687903,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,lifitegrast,DB11611
,2172615,DB11581,10067973,46,1707,80,2680,0.643286957,0.902755985,0.610828332,1.320754628,0.779674352,DB1158110067973_,0.248878944,-0.102302989,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,venetoclax,DB11581
,2174376,DB05316,10038743,27,4329,70,6925,0.035605808,0.617043185,0.379748043,0.976382896,0.096703726,DB0531610038743_,2.336103346,-0.482816266,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,2174620,DB05316,10049848,62,4294,122,6873,0.194708979,0.81345531,0.58780634,1.116037605,0.342645568,DB0531610049848_,1.071058696,-0.20646429,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,pimavanserin,DB05316
,2175229,DB11611,10015958,91,1635,14,369,0.24148032,1.466720092,0.819331284,2.820975698,0.399575683,DB1161110015958_,0.917352089,0.383028678,NA,10015958,Eye pain,10015919,Eye disorders,Eye,lifitegrast,DB11611
,2175429,DB06403,10069326,51,21420,9,6652,0.128916992,1.759698007,0.857451858,4.068242832,0.254035771,DB0640310069326_,1.370280192,0.565142207,NA,10069326,Product substitution issue,10077536,Product issues,Prod,ambrisentan,DB06403
,2177412,DB11569,10037844,107,3378,81,2231,0.364523108,0.87246998,0.644208854,1.185366575,0.534143293,DB1156910037844_,0.627091137,-0.136427032,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ixekizumab,DB11569
,2178086,DB00190,10020765,25,3272,48,4626,0.233916069,0.736389488,0.434174535,1.221087762,0.390727242,DB0019010020765_,0.939745553,-0.305996104,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,carbidopa,DB00190
,2181198,DB09570,10073317,33,3868,36,3899,0.809242261,0.924046988,0.557060821,1.528135499,0.897167018,DB0957010073317_,0.108513238,-0.078992356,NA,10073317,Accidental exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,ixazomib,DB09570
,2182396,DB05316,10053762,123,4233,164,6831,0.124196919,1.210280127,0.946995945,1.54358783,0.24736804,DB0531610053762_,1.396878012,0.190851843,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,pimavanserin,DB05316
,2183790,DB11362,10024774,33,6450,17,2152,0.143510334,0.647696846,0.349739392,1.24246877,0.274809248,DB1136210024774_,1.291678067,-0.434332523,NA,10024774,Localised infection,10021881,Infections and infestations,Infec,selexipag,DB11362
,2191617,DB00126,10061309,46,10125,12,5933,0.009455863,2.246136407,1.169736384,4.66258839,0.034035548,DB0012610061309_,3.380349778,0.809211588,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,ascorbic acid,DB00126
,2192433,DB00588,10051082,39,16485,14,8454,0.309274207,1.428578197,0.758299673,2.850117842,0.476664372,DB0058810051082_,0.740942658,0.356679682,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,fluticasone propionate,DB00588
,2199038,DB09029,10012601,39,11305,26,7244,0.899024635,0.96114063,0.569907135,1.645997218,0.956490275,DB0902910012601_,0.044484657,-0.039634543,NA,10012601,Diabetes mellitus,10027433,Metabolism and nutrition disorders,Metab,secukinumab,DB09029
,2200640,DB11362,10039906,36,6447,16,2153,0.337831649,0.751422656,0.405544972,1.453361526,0.50694725,DB1136210039906_,0.679348325,-0.285786994,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,selexipag,DB11362
,2200787,DB00760,10077361,17,763,42,973,0.022913375,0.516348673,0.273304507,0.93530086,0.068698308,DB0076010077361_,2.678030714,-0.660973019,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,meropenem,DB00760
,2201074,DB05316,10040047,21,4335,42,6953,0.438511665,0.801993511,0.450508723,1.387220489,0.606917785,DB0531610040047_,0.499361941,-0.220654762,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,pimavanserin,DB05316
,2202281,DB11569,10048959,39,3446,18,2294,0.222486283,1.442260741,0.803344144,2.685538358,0.37656484,DB1156910048959_,0.97666503,0.366211842,NA,10048959,Peripheral swelling,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,2204349,DB11611,10023644,67,1659,20,363,0.254782997,0.733120212,0.432840545,1.292556282,0.415509297,DB1161110023644_,0.87825029,-0.310445591,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,lifitegrast,DB11611
,2205398,DB05316,10049438,36,4320,72,6923,0.320251586,0.801304805,0.520593787,1.213948794,0.488484721,DB0531610049438_,0.716447086,-0.221513874,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,2207006,DB11611,10013709,130,1596,28,355,1,1.03271142,0.6697921,1.640692177,1,DB1161110013709_,0,0.03218779,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lifitegrast,DB11611
,2210084,DB11581,10013968,33,1720,60,2700,0.521206944,0.863370142,0.544347112,1.348307581,0.680064167,DB1158110013968_,0.385568122,-0.146911778,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,venetoclax,DB11581
,2211222,DB01015,10077361,37,9850,49,9332,0.130878444,0.715408304,0.453396772,1.120189536,0.257014561,DB0101510077361_,1.358622539,-0.334901845,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,sulfamethoxazole,DB01015
,2220001,DB11362,10047461,48,6435,9,2160,0.124757769,1.790013079,0.866878566,4.156761625,0.248212388,DB1136210047461_,1.393470495,0.582222927,NA,10047461,Viral infection,10021881,Infections and infestations,Infec,selexipag,DB11362
,2222063,DB08904,10061822,62,11548,8,3551,0.015697782,2.383107846,1.135805293,5.768677155,0.051091655,DB0890410061822_,2.974134102,0.868405454,NA,10061822,Drug intolerance,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,2224962,DB05316,10036436,11,4345,47,6948,0.001749134,0.374283014,0.174864085,0.733162002,0.008704277,DB0531610036436_,4.743940814,-0.982743046,NA,10036436,Posture abnormal,10028395,Musculoskeletal and connective tissue disorders,Musc,pimavanserin,DB05316
,2227066,DB00921,10053425,27,5818,37,4866,0.05851913,0.610359958,0.356846858,1.031587089,0.140716799,DB0092110053425_,1.961005929,-0.4937064,NA,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,2227553,DB09303,10051082,149,26082,61,18898,0.000141828,1.76980113,1.304589764,2.426330525,0.001075265,DB0930310051082_,6.835187697,0.570867184,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,2228984,DB05316,10005734,23,4333,47,6948,0.388930627,0.784724482,0.454102904,1.320634056,0.558804096,DB0531610005734_,0.581956322,-0.242422601,NA,10005734,Blood pressure decreased,10022891,Investigations,Inv,pimavanserin,DB05316
,2234363,DB05316,10029412,59,4297,101,6894,0.743553994,0.937207313,0.666391473,1.308039861,0.853389082,DB0531610029412_,0.158539702,-0.064850769,NA,10029412,Nightmare,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,2234909,DB08907,10017711,33,4220,58,3852,0.002935821,0.519395148,0.327326818,0.811851015,0.013273939,DB0890710017711_,4.321952648,-0.655090322,NA,10017711,Gangrene,10021881,Infections and infestations,Infec,canagliflozin,DB08907
,2236715,DB11581,10025482,28,1725,33,2727,0.290115528,1.341227652,0.777849965,2.297989478,0.455305648,DB1158110025482_,0.786786331,0.293585353,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,venetoclax,DB11581
,2236754,DB00019,10064385,145,18867,70,9459,0.827915335,1.038501159,0.774646274,1.4034322,0.909547717,DB0001910064385_,0.094807818,0.03777848,NA,10064385,Circumstance or information capable of leading to medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,2240766,DB11362,10010305,82,6401,25,2144,0.737363184,1.098615838,0.692577989,1.799806068,0.848609412,DB1136210010305_,0.164156256,0.094051058,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,selexipag,DB11362
,2240861,DB05679,10051082,83,6848,51,4858,0.480664304,1.154476177,0.803266963,1.673308553,0.645444902,DB0567910051082_,0.437815429,0.143646715,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,2247992,DB05316,10012378,41,4315,43,6952,0.055287354,1.536074336,0.974827247,2.417450899,0.134851585,DB0531610012378_,2.003580478,0.429230029,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,2252419,DB11611,10013774,77,1649,12,371,0.324239823,1.443416296,0.770619113,2.945194827,0.492666845,DB1161110013774_,0.707922105,0.367012731,NA,10013774,Dry eye,10015919,Eye disorders,Eye,lifitegrast,DB11611
,2252592,DB11581,10061428,19,1734,31,2729,1,0.964603041,0.513134286,1.768614943,1,DB1158110061428_,0,-0.036038619,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,venetoclax,DB11581
,2252876,DB11581,10028813,64,1689,67,2693,0.018117217,1.522844516,1.057958025,2.190476669,0.057130473,DB1158110028813_,2.862417619,0.420579978,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,venetoclax,DB11581
,2252877,DB11581,10047700,42,1711,38,2722,0.014629659,1.758049894,1.10146901,2.814406353,0.048333407,DB1158110047700_,3.02963231,0.56420518,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,venetoclax,DB11581
,2253049,DB11569,10033425,38,3447,22,2290,0.691524016,1.147518125,0.659616049,2.0426337,0.814003975,DB1156910033425_,0.20579003,0.137601458,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ixekizumab,DB11569
,2253967,DB11569,10037087,86,3399,58,2254,0.931475984,0.983268486,0.693460241,1.40273811,0.972488084,DB1156910037087_,0.027897457,-0.016873067,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ixekizumab,DB11569
,2254260,DB11581,10003658,17,1736,53,2707,0.012958911,0.500233848,0.270599747,0.881139118,0.043765253,DB1158110003658_,3.128915077,-0.692679594,NA,10003658,Atrial fibrillation,10007541,Cardiac disorders,Card,venetoclax,DB11581
,2255578,DB11569,10037153,146,3339,125,2187,0.035864659,0.765072103,0.594576295,0.985573604,0.097261034,DB1156910037153_,2.330356845,-0.267785197,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,ixekizumab,DB11569
,2261010,DB00704,10001605,23,4333,36,5158,0.35911691,0.760555382,0.429572317,1.321341752,0.528906145,DB0070410001605_,0.636944282,-0.273706347,NA,10001605,Alcohol poisoning,10022117,"Injury, poisoning and procedural complications",Inj&P,naltrexone,DB00704
,2262580,DB11569,10006451,38,3447,16,2296,0.12718904,1.581835468,0.858852674,3.046308634,0.251715839,DB1156910006451_,1.379454452,0.458585861,NA,10006451,Bronchitis,10021881,Infections and infestations,Infec,ixekizumab,DB11569
,2262581,DB11569,10035664,44,3441,23,2289,0.381653112,1.27252939,0.74959806,2.214138594,0.551786368,DB1156910035664_,0.594594323,0.241006566,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ixekizumab,DB11569
,2268874,DB05316,10019075,142,4214,203,6792,0.285757127,1.127429827,0.900153921,1.409047629,0.450415333,DB0531610019075_,0.797585161,0.119940553,NA,10019075,"Hallucination, visual",10037175,Psychiatric disorders,Psych,pimavanserin,DB05316
,2270502,DB05351,10061481,101,2622,68,1063,0.002381791,0.602247756,0.434657441,0.838673826,0.011220133,DB0535110061481_,4.490045529,-0.507086364,NA,10061481,Renal injury,10038359,Renal and urinary disorders,Renal,dexlansoprazole,DB05351
,2273063,DB06616,10061309,32,929,36,767,0.216701629,0.734019625,0.436846991,1.228442551,0.369534341,DB0661610061309_,0.995511604,-0.309219514,NA,10061309,Neoplasm progression,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,bosutinib,DB06616
,2280253,DB09263,10016173,31,1360,26,1694,0.141691301,1.484914509,0.848646156,2.617573982,0.272108997,DB0926310016173_,1.301552567,0.395357201,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,patiromer,DB09263
,2281157,DB05316,10029719,108,4248,182,6813,0.713889814,0.951712961,0.740662932,1.218147345,0.83029176,DB0531610029719_,0.185978122,-0.049491801,NA,10029719,Nonspecific reaction,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,2288258,DB11569,10019211,72,3413,32,2280,0.068400089,1.502974659,0.974477224,2.364311361,0.158391019,DB1156910019211_,1.842688498,0.40744625,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ixekizumab,DB11569
,2292060,DB06791,10013709,35,744,18,520,0.321266999,1.358712348,0.739556213,2.577920124,0.489564791,DB0679110013709_,0.714238465,0.306537448,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,lanreotide,DB06791
,2298763,DB11569,10003239,72,3413,58,2254,0.277601294,0.819862009,0.569578104,1.18442791,0.44122449,DB1156910003239_,0.818201484,-0.198619235,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ixekizumab,DB11569
,2311970,DB11362,10019641,34,6449,23,2146,0.013071443,0.491941243,0.280752048,0.876765347,0.04408017,DB1136210019641_,3.121745261,-0.709395994,NA,10019641,Hepatic cirrhosis,10019805,Hepatobiliary disorders,Hepat,selexipag,DB11362
,2318914,DB11362,10005557,32,6451,26,2143,0.001147787,0.408906119,0.235477472,0.716165727,0.006175332,DB1136210005557_,5.087192627,-0.894269686,NA,10005557,Blood glucose increased,10022891,Investigations,Inv,selexipag,DB11362
,2329847,DB09303,10005728,30,26201,22,18937,1,0.98557701,0.549633555,1.793687849,1,DB0930310005728_,0,-0.014528012,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,evolocumab,DB09303
,2330080,DB11569,10020751,46,3439,26,2286,0.546697957,1.175992287,0.709542549,1.987880682,0.70138402,DB1156910020751_,0.354699725,0.162112291,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ixekizumab,DB11569
,2334389,DB09303,10056819,59,26172,39,18920,0.683441347,1.093653237,0.717285756,1.684150075,0.808636124,DB0930310056819_,0.212406248,0.089523686,NA,10056819,Gastric disorder,10017947,Gastrointestinal disorders,Gastr,evolocumab,DB09303
,2340036,DB09292,10057362,29,4500,46,8216,0.547169351,1.151013518,0.696258329,1.874570246,0.701783273,DB0929210057362_,0.354130651,0.140642875,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,sacubitril,DB09292
,2351112,DB11362,10013950,48,6435,14,2155,0.768967366,1.148165078,0.621150831,2.259652234,0.873452361,DB1136210013950_,0.135301689,0.138165084,NA,10013950,Dysphagia,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,2353898,DB11362,10067973,51,6432,24,2145,0.180359457,0.708694423,0.42709666,1.206982212,0.324286773,DB1136210067973_,1.126127053,-0.344330842,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,selexipag,DB11362
,2358417,DB01097,10051082,40,6225,10,1493,0.85840022,0.959358061,0.47011222,2.156416192,0.932511564,DB0109710051082_,0.069873727,-0.041490905,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,leflunomide,DB01097
,2363722,DB00207,10076308,31,9049,27,5428,0.174301036,0.688752678,0.397335189,1.200764879,0.316533282,DB0020710076308_,1.150326887,-0.37287303,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,azithromycin,DB00207
,2365690,DB09029,10061520,38,11306,15,7255,0.121536211,1.625585068,0.8728334,3.183520588,0.243637837,DB0902910061520_,1.412072432,0.485867793,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,2384737,DB11362,10007515,59,6424,25,2144,0.313274429,0.787667723,0.484309086,1.316063581,0.480841948,DB1136210007515_,0.732216654,-0.238678949,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,selexipag,DB11362
,2385773,DB00213,10077512,160,18735,164,13257,0.000991789,0.690368642,0.551091851,0.864643457,0.005465399,DB0021310077512_,5.209318095,-0.37052956,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,pantoprazole,DB00213
,2389319,DB11362,10013781,53,6430,15,2154,0.673734534,1.183612936,0.655654759,2.265878477,0.802138219,DB1136210013781_,0.220474343,0.168571571,NA,10013781,Dry mouth,10017947,Gastrointestinal disorders,Gastr,selexipag,DB11362
,2393989,DB11611,10065653,54,1672,14,369,0.630847371,0.851345276,0.460333761,1.678027212,0.769702826,DB1161110065653_,0.26175078,-0.160937502,NA,10065653,Instillation site lacrimation,10018065,General disorders and administration site conditions,Genrl,lifitegrast,DB11611
,2394760,DB11611,10063763,70,1656,8,375,0.071925198,1.980870426,0.941137344,4.809374313,0.164653704,DB1161110063763_,1.803910773,0.683536357,NA,10063763,Instillation site pruritus,10018065,General disorders and administration site conditions,Genrl,lifitegrast,DB11611
,2396263,DB11362,10019196,39,6444,11,2158,0.743884354,1.187293304,0.59502049,2.575275674,0.853637783,DB1136210019196_,0.158248316,0.171676182,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,selexipag,DB11362
,2397813,DB09302,10069803,55,2143,20,1527,0.009040241,1.95918325,1.150007329,3.4661203,0.032841232,DB0930210069803_,3.416070494,0.672527677,NA,10069803,Injury associated with device,10018065,General disorders and administration site conditions,Genrl,alirocumab,DB09302
,2398164,DB05316,10012174,31,4325,52,6943,0.910042838,0.95701664,0.591856175,1.524164642,0.959542868,DB0531610012174_,0.041298287,-0.0439345,NA,10012174,Dehydration,10027433,Metabolism and nutrition disorders,Metab,pimavanserin,DB05316
,2401754,DB08895,10005728,46,28068,12,6634,0.738836126,0.906009963,0.471982173,1.880044387,0.849736707,DB0889510005728_,0.162828734,-0.098704977,NA,10005728,Blood pressure abnormal,10022891,Investigations,Inv,tofacitinib,DB08895
,2404034,DB11611,10063762,67,1659,11,372,0.453397579,1.365582919,0.707584629,2.8947635,0.620948566,DB1161110063762_,0.476507025,0.311581385,NA,10063762,Instillation site erythema,10018065,General disorders and administration site conditions,Genrl,lifitegrast,DB11611
,2409634,DB05676,10078115,45,47084,41,25288,0.017021078,0.589460381,0.377333279,0.923256474,0.054441353,DB0567610078115_,2.910631254,-0.52854777,NA,10078115,Therapy partial responder,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,2410242,DB09263,10053762,112,1279,129,1591,0.589738497,1.079983158,0.821752522,1.417701839,0.736525141,DB0926310053762_,0.305811908,0.076945447,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,patiromer,DB09263
,2414260,DB00190,10029719,33,3264,62,4612,0.208901737,0.752102058,0.476284722,1.168485107,0.359969985,DB0019010029719_,1.021734627,-0.284883249,NA,10029719,Nonspecific reaction,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,2418100,DB12332,10016256,1258,2252,7,71,1.0836685272188e-07,5.66499779,2.599778196,14.647338,1.95164283918781e-06,DB1233210016256_,13.14683906,1.734306504,female,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,rucaparib,DB12332
,2418102,DB12332,10028813,1199,2311,6,72,7.91069888290574e-08,6.224400934,2.712877851,17.56890396,1.46328444853749e-06,DB1233210028813_,13.43482703,1.828477202,female,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,rucaparib,DB12332
,2418943,DB11569,10022000,49,3436,38,2274,0.508363654,0.853422133,0.545340886,1.344567487,0.668934342,DB1156910022000_,0.402069367,-0.158500973,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ixekizumab,DB11569
,2419641,DB11581,10018884,30,1723,70,2690,0.077368121,0.669155712,0.419220538,1.045137392,0.173880643,DB1158110018884_,1.749386175,-0.401738492,NA,10018884,Haemoglobin decreased,10022891,Investigations,Inv,venetoclax,DB11581
,2420521,DB12332,10012735,372,3138,7,71,0.851680331,1.202308496,0.548641542,3.121734745,0.92716577,DB1233210012735_,0.075622905,0.184243456,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,rucaparib,DB12332
,2420808,DB09331,10022000,28,2057,36,2393,0.707139179,0.904866844,0.5298628,1.530799091,0.824867567,DB0933110022000_,0.19253243,-0.099967479,NA,10022000,Influenza,10021881,Infections and infestations,Infec,daratumumab,DB09331
,2420943,DB11569,10040753,72,3413,42,2270,0.562463298,1.140189831,0.765587433,1.716874489,0.71472035,DB1156910040753_,0.335863932,0.131194767,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,ixekizumab,DB11569
,2421993,DB11569,10065154,125,3360,84,2228,0.942706734,0.986747767,0.738329863,1.324158471,0.981737183,DB1156910065154_,0.018431641,-0.013340827,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,ixekizumab,DB11569
,2422061,DB05219,10006784,194,1024,93,531,0.587669566,1.081684769,0.821333796,1.431665795,0.734656832,DB0521910006784_,0.308351784,0.078519797,NA,10006784,Burning sensation,10029205,Nervous system disorders,Nerv,crisaborole,DB05219
,2422062,DB05219,10015150,52,1166,29,595,0.719533319,0.915052432,0.563471617,1.511730219,0.834455473,DB0521910015150_,0.180975895,-0.088773912,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,crisaborole,DB05219
,2423479,DB01248,10076573,63,2637,19,1355,0.044584526,1.703587717,1.001557053,3.027115242,0.114744025,DB0124810076573_,2.165051497,0.532736449,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,docetaxel,DB01248
,2424010,DB09303,10064385,36,26195,24,18935,0.794854337,1.084288368,0.629053868,1.900542107,0.88886159,DB0930310064385_,0.117813747,0.08092389,NA,10064385,Circumstance or information capable of leading to medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,2425358,DB05219,10003051,320,898,152,472,0.397769004,1.106456602,0.880852378,1.393411968,0.567460004,DB0521910003051_,0.566585009,0.101162659,NA,10003051,Application site pain,10018065,General disorders and administration site conditions,Genrl,crisaborole,DB05219
,2428993,DB06724,10077512,38,7891,47,3872,2.44905110345292e-05,0.396756359,0.251273236,0.622855389,0.000237321,DB0672410077512_,8.346097105,-0.924432892,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,calcium carbonate,DB06724
,2431061,DB00480,10038647,35,67393,40,67622,0.644409045,0.877974619,0.541392793,1.417813724,0.780476932,DB0048010038647_,0.247850094,-0.130137593,NA,10038647,Respiration abnormal,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,lenalidomide,DB00480
,2433695,DB05219,10033371,105,1113,61,563,0.439249426,0.870781219,0.618353434,1.234630579,0.607635199,DB0521910033371_,0.498180579,-0.138364518,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,crisaborole,DB05219
,2434485,DB12332,10053762,155,3355,18,60,1.40233004947995e-08,0.154194945,0.087226931,0.284450914,3.04630126864302e-07,DB1233210053762_,15.0041675,-1.8695376,male,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,rucaparib,DB12332
,2435718,DB00005,10078390,66,128016,22,42397,1,0.993555446,0.605085474,1.691091909,1,DB0000510078390_,0,-0.00646541,NA,10078390,Incorrect disposal of product,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,2438302,DB00704,10066169,35,4321,47,5147,0.656469731,0.887059144,0.554706945,1.40649996,0.789956965,DB0070410066169_,0.23577681,-0.119843621,NA,10066169,Substance abuse,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,2445164,DB11581,10003988,26,1727,31,2729,0.338440908,1.32521714,0.752948064,2.315359698,0.507497248,DB1158110003988_,0.67826399,0.281576325,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,venetoclax,DB11581
,2447588,DB05219,10010264,70,1148,41,583,0.471264255,0.867118758,0.573428744,1.325458809,0.63748891,DB0521910010264_,0.450218398,-0.142579335,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,crisaborole,DB05219
,2447589,DB05219,10037087,40,1178,21,603,1,0.975013192,0.555564076,1.757216821,1,DB0521910037087_,0,-0.025304277,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,crisaborole,DB05219
,2449628,DB00019,10072931,3192,15820,1586,7943,0.762232687,1.01050332,0.94557894,1.080192423,0.868285351,DB0001910072931_,0.141234873,0.010448544,NA,10072931,Unintentional medical device removal,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,2449909,DB09303,10003051,35,26196,15,18944,0.113814884,1.687358804,0.897666324,3.326802909,0.231872906,DB0930310003051_,1.461565878,0.523164468,NA,10003051,Application site pain,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,2450321,DB11569,10046306,41,3444,16,2296,0.076978809,1.708183016,0.935360184,3.269116489,0.173124106,DB1156910046306_,1.753746565,0.535430242,NA,10046306,Upper respiratory tract infection,10021881,Infections and infestations,Infec,ixekizumab,DB11569
,2451392,DB11569,10028810,70,3415,52,2260,0.575220821,0.890885986,0.610826597,1.306491713,0.7246849,DB1156910028810_,0.322018339,-0.115538821,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ixekizumab,DB11569
,2451931,DB00019,10073311,317,18695,33,9496,7.32943163838279e-26,4.879781147,3.399987956,7.217374812,1.19290470968973e-23,DB0001910073311_,52.78306587,1.585100372,female,10073311,Occupational exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,2452014,DB00958,10076573,68,4526,14,2571,0.00018836,2.758772983,1.533070035,5.321692352,0.0013711,DB0095810076573_,6.592141936,1.014786009,female,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,carboplatin,DB00958
,2452142,DB11611,10053762,66,1660,6,377,0.028332521,2.497424286,1.076996156,7.103408221,0.081009497,DB1161110053762_,2.513188884,0.915259915,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,lifitegrast,DB11611
,2453286,DB11581,10000880,70,1683,116,2644,0.759038873,0.948024798,0.689862346,1.295038362,0.865624087,DB1158110000880_,0.144304545,-0.053374619,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,venetoclax,DB11581
,2453528,DB00864,10076664,20,6849,34,8358,0.27379184,0.717854162,0.391154467,1.284680447,0.436847063,DB0086410076664_,0.828172115,-0.331488848,NA,10076664,Delayed graft function,10022117,"Injury, poisoning and procedural complications",Inj&P,tacrolimus,DB00864
,2458273,DB08895,10054889,36,28078,15,6631,0.073241865,0.566804184,0.302466925,1.114985769,0.166911948,DB0889510054889_,1.79028886,-0.567741389,NA,10054889,Transaminases increased,10022891,Investigations,Inv,tofacitinib,DB08895
,2463147,DB05990,10054112,54,1305,8,159,0.538159149,0.822530167,0.379862853,2.038373064,0.694140288,DB0599010054112_,0.365081195,-0.195370119,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,obeticholic acid,DB05990
,2471794,DB00736,10077512,151,10440,142,5411,5.88229171771843e-07,0.5511422,0.434315027,0.699790999,8.94509909171125e-06,DB0073610077512_,11.62440476,-0.595762427,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,esomeprazole,DB00736
,2472907,DB00065,10051082,54,9410,22,4935,0.335823361,1.287282337,0.769875871,2.22238312,0.504969369,DB0006510051082_,0.683257507,0.252533281,NA,10051082,Therapy non-responder,10018065,General disorders and administration site conditions,Genrl,infliximab,DB00065
,2480554,DB00190,10051076,29,3268,85,4589,0.000508728,0.479131602,0.302247174,0.740047597,0.003132573,DB0019010051076_,5.765900564,-0.735779976,NA,10051076,Prescribed overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,carbidopa,DB00190
,2481200,DB12001,10016256,114,1512,7,49,0.116413955,0.528019,0.230776976,1.413583349,0.235751824,DB1200110016256_,1.44497562,-0.638623011,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,abemaciclib,DB12001
,2482619,DB00073,10077361,34,7372,23,6384,0.424983069,1.280119097,0.731484827,2.278626249,0.593735827,DB0007310077361_,0.521320794,0.246953118,NA,10077361,Multiple organ dysfunction syndrome,10018065,General disorders and administration site conditions,Genrl,rituximab,DB00073
,2483766,DB05219,10037844,52,1166,30,594,0.63337976,0.883084545,0.546340923,1.45014197,0.771991699,DB0521910037844_,0.258781481,-0.124334335,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,crisaborole,DB05219
,2490458,DB09263,10003549,33,1358,20,1700,0.011648793,2.065077761,1.144461629,3.816172764,0.040213887,DB0926310003549_,3.213542896,0.725167883,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,patiromer,DB09263
,2495946,DB01073,10066901,28,1037,32,1618,0.232335317,1.365046953,0.786818333,2.355912901,0.388766196,DB0107310066901_,0.944777154,0.311188826,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,fludarabine,DB01073
,2511441,DB00704,10022112,72,4284,22,5172,9.71421134532572e-10,3.950582325,2.417113952,6.702887747,2.70772052186518e-08,DB0070410022112_,17.4245736,1.373862992,female,10022112,Injection site warmth,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,2511444,DB00704,10076573,65,4291,52,5142,0.031748013,1.497821776,1.021674788,2.205380614,0.088535717,DB0070410076573_,2.424349227,0.404011904,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,naltrexone,DB00704
,2517064,DB12332,10011906,121,3389,7,71,0.020110602,0.362301858,0.162266334,0.953512743,0.062024897,DB1233210011906_,2.780219408,-1.015277553,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,rucaparib,DB12332
,2525948,DB00210,10046735,37,848,16,333,0.756239734,0.9081698,0.48514755,1.77359308,0.863368359,DB0021010046735_,0.146913844,-0.096323913,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,adapalene,DB00210
,2528829,DB05219,10013709,177,1041,108,516,0.134131841,0.812468434,0.620938702,1.066328499,0.261508341,DB0521910013709_,1.3412891,-0.207678217,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,crisaborole,DB05219
,2528901,DB05219,10003041,56,1162,30,594,0.816747066,0.954243468,0.594631364,1.557985953,0.901911382,DB0521910003041_,0.10323901,-0.046836433,NA,10003041,Application site erythema,10018065,General disorders and administration site conditions,Genrl,crisaborole,DB05219
,2545716,DB01073,10029350,74,991,106,1544,0.635619518,1.0876408,0.788286259,1.494373383,0.773537932,DB0107310029350_,0.25678057,0.084010947,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,fludarabine,DB01073
,2547583,DB09045,10074904,47,2302,41,1683,0.445722018,0.838134567,0.536782102,1.313281019,0.613581754,DB0904510074904_,0.488441765,-0.17657661,NA,10074904,Accidental underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,dulaglutide,DB09045
,2548956,DB05316,10000087,35,4321,22,6973,0.000526629,2.567114975,1.46205903,4.599882361,0.003221423,DB0531610000087_,5.737932076,0.942782691,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,pimavanserin,DB05316
,2550483,DB00005,10078156,105,127977,53,42366,0.016267602,0.655843705,0.466948958,0.930769058,0.052520288,DB0000510078156_,2.946555755,-0.421832773,NA,10078156,Insurance issue,10041244,Social circumstances,SocCi,etanercept,DB00005
,2568457,DB00073,10076573,40,7366,17,6390,0.015844217,2.041027951,1.129884466,3.843682554,0.051454081,DB0007310076573_,2.967065507,0.713453578,NA,10076573,Wrong technique in product usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,rituximab,DB00073
,2580836,DB11581,10054112,42,1711,61,2699,0.683709339,1.086085121,0.711666827,1.64378036,0.808807578,DB1158110054112_,0.212194242,0.082579599,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,venetoclax,DB11581
,2581604,DB11569,10011224,32,3453,20,2292,0.887618244,1.062030534,0.587397015,1.964530363,0.953401944,DB1156910011224_,0.047718698,0.060182674,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ixekizumab,DB11569
,2593603,DB09292,10042209,38,4491,23,8239,2.12175192906483e-05,3.030730991,1.757325697,5.335867293,0.000210057,DB0929210042209_,8.468129556,1.108803842,female,10042209,Stress,10037175,Psychiatric disorders,Psych,sacubitril,DB09292
,2598041,DB00836,10038678,12,5523,45,4030,2.07141100419781e-08,0.194606716,0.093571528,0.374666032,4.32634392096459e-07,DB0083610038678_,14.65337283,-1.6367746,male,10038678,Respiratory depression,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,loperamide,DB00836
,2599008,DB05990,10037844,38,1321,12,155,0.008553771,0.371901234,0.185392842,0.798865813,0.031414822,DB0599010037844_,3.460475465,-0.989126959,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,obeticholic acid,DB05990
,2607218,DB05219,10013700,50,1168,21,603,0.522764228,1.229031482,0.717046579,2.17572606,0.68123201,DB0521910013700_,0.383852341,0.206226446,NA,10013700,Drug hypersensitivity,10021428,Immune system disorders,Immun,crisaborole,DB05219
,2675239,DB11569,10033371,66,3419,36,2276,0.360095222,1.22037711,0.798129223,1.89294098,0.529931298,DB1156910033371_,0.635007907,0.199159918,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ixekizumab,DB11569
,2682723,DB00019,10064382,32,18980,20,9509,0.462770412,0.801627112,0.444321162,1.479739342,0.630010114,DB0001910064382_,0.462019406,-0.221111727,NA,10064382,Intercepted medication error,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,2694563,DB00230,10076476,423,19251,161,8490,0.12267704,1.158679869,0.96229363,1.400652481,0.24526365,DB0023010076476_,1.405421524,0.147281313,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,2694564,DB00482,10076476,81,8178,26,3045,0.585111425,1.159964565,0.736041635,1.884258772,0.732678472,DB0048210076476_,0.31104832,0.148389457,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,celecoxib,DB00482
,2695127,DB00175,10076476,44,8087,41,6065,0.324483662,0.804862277,0.51316017,1.264784363,0.492951859,DB0017510076476_,0.707343759,-0.217084101,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,2695128,DB00264,10076476,195,29412,148,24744,0.35573792,1.10842341,0.889995396,1.382935617,0.525445828,DB0026410076476_,0.64350818,0.102938655,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,2695129,DB00635,10076476,543,32510,526,23268,1.01701999630247e-06,0.738864046,0.653372284,0.835610991,1.452451540495e-05,DB0063510076476_,11.13967262,-0.302641345,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,2695130,DB00695,10076476,141,27908,106,20422,0.846564167,0.973370689,0.750708706,1.265283292,0.922995277,DB0069510076476_,0.080131162,-0.026990294,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,2695132,DB06228,10076476,94,15818,105,15971,0.522279142,0.903906394,0.676316636,1.206611334,0.680939225,DB0622810076476_,0.384282221,-0.101029471,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,2695133,DB06605,10076476,71,14002,59,12974,0.597745449,1.115023365,0.777641787,1.603967061,0.742836704,DB0660510076476_,0.297279038,0.10887536,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,2695253,DB00196,10076476,55,5028,59,3226,0.006759542,0.598166975,0.405447369,0.881222784,0.026063454,DB0019610076476_,3.64722119,-0.513885341,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,fluconazole,DB00196
,2695254,DB00404,10076476,115,19777,46,9816,0.240041366,1.240792428,0.873434347,1.788540173,0.397886634,DB0040410076476_,0.921588153,0.21575023,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,2695255,DB00472,10076476,72,10687,33,4279,0.516796343,0.873604467,0.570037387,1.364210707,0.676445498,DB0047210076476_,0.3909034,-0.13512756,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,2695256,DB00836,10076476,45,5490,24,4051,0.222310831,1.383491567,0.823615621,2.378388405,0.376405129,DB0083610076476_,0.977089244,0.324610425,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,loperamide,DB00836
,2695257,DB01268,10076476,61,2082,68,3062,0.123573042,1.319216032,0.913802923,1.900945035,0.246499007,DB0126810076476_,1.400397315,0.277037645,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,sunitinib,DB01268
,2695836,DB00254,10076476,61,5874,46,3342,0.157564775,0.754517503,0.504875086,1.134347889,0.294244442,DB0025410076476_,1.223344423,-0.281676804,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,doxycycline,DB00254
,2695837,DB00316,10076476,466,65008,222,36731,0.03829335,1.186009111,1.008141517,1.398713002,0.102218007,DB0031610076476_,2.280647422,0.170593983,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,2695838,DB00343,10076476,32,8704,23,5072,0.4843,0.81076521,0.459254963,1.452648805,0.648455275,DB0034310076476_,0.433162244,-0.209776774,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,2696746,DB00704,10078575,125,4231,158,5036,0.628531725,0.941653679,0.735955074,1.202759808,0.76779163,DB0070410078575_,0.264236898,-0.060117717,NA,10078575,Therapeutic response shortened,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,2696751,DB00704,10079381,52,4304,89,5105,0.040648322,0.693033301,0.481283821,0.989159126,0.106938956,DB0070410079381_,2.235497112,-0.366677228,NA,10079381,Drug use disorder,10037175,Psychiatric disorders,Psych,naltrexone,DB00704
,2697032,DB00704,10054266,29,4327,41,5153,0.547514543,0.842355405,0.503952155,1.391364561,0.702157483,DB0070410054266_,0.353597566,-0.171553258,NA,10054266,Injection site discomfort,10018065,General disorders and administration site conditions,Genrl,naltrexone,DB00704
,2697033,DB00704,10069217,46,4310,88,5106,0.008655013,0.619299875,0.422794828,0.896745821,0.0317268,DB0070410069217_,3.450593526,-0.479165673,NA,10069217,Needle issue,10077536,Product issues,Prod,naltrexone,DB00704
,2698064,DB00190,10078575,30,3267,23,4651,0.025527604,1.85671562,1.040712164,3.353685955,0.074670939,DB0019010078575_,2.594664295,0.618809131,NA,10078575,Therapeutic response shortened,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,2698113,DB00682,10076476,76,19383,52,16312,0.286149011,1.229967441,0.852548644,1.786611751,0.450870804,DB0068210076476_,0.796574446,0.206987698,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,2698916,DB00421,10076476,68,8835,44,5208,0.624865694,0.911012482,0.613438748,1.365242822,0.764509819,DB0042110076476_,0.26852041,-0.09319868,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,spironolactone,DB00421
,2698917,DB00451,10076476,346,46925,114,15305,0.913539046,0.989920414,0.798179996,1.23526504,0.961302297,DB0045110076476_,0.039466354,-0.010130729,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,2698920,DB01373,10076476,134,22586,29,7352,0.044746169,1.504032167,0.999843813,2.333588211,0.115083468,DB0137310076476_,2.162097601,0.408149613,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,2698921,DB09053,10076476,45,2240,46,4006,0.008313481,1.749445021,1.129736327,2.707352206,0.030703928,DB0905310076476_,3.48336467,0.559298607,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,ibrutinib,DB09053
,2699430,DB00904,10076476,338,22731,90,14366,7.34623900521679e-15,2.373454381,1.874002735,3.03218143,4.41362039433425e-13,DB0090410076476_,28.44891091,0.864346439,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,2699573,DB00051,10079487,148,25583,49,11371,0.075263439,1.342431861,0.965021236,1.895916094,0.170278834,DB0005110079487_,1.770317985,0.29448279,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,adalimumab,DB00051
,2700100,DB00437,10076476,34,6887,51,11495,0.653938823,1.112715228,0.698270508,1.753047331,0.787852518,DB0043710076476_,0.238444366,0.106803179,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,allopurinol,DB00437
,2700101,DB00706,10076476,9,1066,82,15843,0.187996388,1.631135808,0.718321245,3.262351029,0.334030829,DB0070610076476_,1.096521988,0.489276587,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,tamsulosin,DB00706
,2700102,DB00722,10076476,162,25241,149,25883,0.362819369,1.114899414,0.886326789,1.403181592,0.532345704,DB0072210076476_,0.630462182,0.108764189,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,2700103,DB00863,10076476,68,10605,35,5805,0.836453867,1.063488445,0.696441794,1.650024842,0.915542875,DB0086310076476_,0.088238083,0.061554491,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,2700105,DB00983,10076476,52,3449,24,1716,0.807310846,1.077976611,0.650142016,1.835062356,0.895894857,DB0098310076476_,0.10993222,0.075085776,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,formoterol,DB00983
,2700106,DB00999,10076476,116,21314,47,12192,0.049879862,1.411776141,0.996986493,2.027464983,0.124788672,DB0099910076476_,2.081133594,0.344848586,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,2700107,DB01060,10076476,56,8531,22,5059,0.12601003,1.509446171,0.905720786,2.599572677,0.250107502,DB0106010076476_,1.385864445,0.411742809,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,amoxicillin,DB01060
,2700426,DB00126,10076476,61,10110,33,5912,0.74902324,1.080937963,0.695583887,1.706851729,0.857606649,DB0012610076476_,0.153609735,0.077829148,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,ascorbic acid,DB00126
,2700427,DB00169,10076476,199,38492,78,18097,0.196310329,1.199463182,0.918137419,1.580230246,0.344577708,DB0016910076476_,1.065435648,0.181874108,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,2700428,DB00338,10076476,220,33454,114,22158,0.033246093,1.278195582,1.014202195,1.618116644,0.091811805,DB0033810076476_,2.388014397,0.245449382,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,2700429,DB00455,10076476,107,9294,45,5073,0.147773406,1.297874029,0.906423606,1.885103831,0.280894571,DB0045510076476_,1.269775874,0.260727563,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,2700430,DB00476,10076476,99,17158,41,6136,0.441691708,0.863539313,0.593592968,1.276508475,0.609894929,DB0047610076476_,0.494468584,-0.146715855,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,2700431,DB00641,10076476,80,14044,55,12420,0.166597468,1.28633276,0.900419076,1.849304379,0.306250378,DB0064110076476_,1.183352283,0.251795348,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,2700432,DB00829,10076476,53,7999,17,4437,0.059550224,1.729271323,0.984155404,3.189952597,0.142648104,DB0082910076476_,1.947374491,0.547700119,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,2700433,DB09029,10076476,78,11266,33,7237,0.050537883,1.518308341,0.997365181,2.358198028,0.125995726,DB0902910076476_,2.071507297,0.417596781,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,2700435,DB13961,10076476,57,9400,36,6378,0.832279989,1.074316121,0.694751007,1.680968444,0.912527563,DB1396110076476_,0.091536988,0.071684292,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,fish oil,DB13961
,2700453,DB00321,10076476,56,7391,23,2827,0.80083191,0.931286705,0.562597684,1.589020858,0.892302696,DB0032110076476_,0.113949858,-0.071188096,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,amitriptyline,DB00321
,2700454,DB00335,10076476,50,8416,19,5446,0.04822614,1.702833679,0.985071646,3.062043358,0.121763997,DB0033510076476_,2.105670562,0.532293733,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,atenolol,DB00335
,2700455,DB00814,10076476,50,8237,24,3391,0.523554908,0.857690952,0.516322436,1.46173416,0.681717293,DB0081410076476_,0.383140234,-0.15351144,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,meloxicam,DB00814
,2700456,DB00924,10076476,68,10094,15,4236,0.021576535,1.90236389,1.074922716,3.587769937,0.06565251,DB0092410076476_,2.723379441,0.643097265,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,2700457,DB00956,10076476,55,5759,28,3439,0.569074581,1.172993433,0.729703196,1.924404278,0.720103732,DB0095610076476_,0.328360005,0.159558971,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocodone,DB00956
,2700458,DB00996,10076476,563,38390,252,22173,0.000748278,1.290369924,1.109239847,1.504456227,0.004325122,DB0099610076476_,5.443314818,0.25492894,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,2701472,DB00046,10076476,36,5423,22,4670,0.235066881,1.409099796,0.80548984,2.518064227,0.392101344,DB0004610076476_,0.936234943,0.342951058,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin lispro,DB00046
,2701473,DB00047,10076476,40,9245,29,8489,0.398210599,1.266499989,0.765050694,2.1202838,0.567992489,DB0004710076476_,0.565647083,0.236257181,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,2701474,DB00381,10076476,180,29180,114,22773,0.087324294,1.232255126,0.96851451,1.573134167,0.190640786,DB0038110076476_,1.657364322,0.208845927,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,2701476,DB01075,10076476,167,19781,101,10996,0.522262569,0.919143851,0.712844026,1.190078423,0.680939225,DB0107510076476_,0.384282221,-0.084312639,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,2701477,DB01098,10076476,54,8095,35,7174,0.166340212,1.367289716,0.876241847,2.158472215,0.305907665,DB0109810076476_,1.184471972,0.312830471,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,rosuvastatin,DB01098
,2701478,DB09037,10076476,238,2288,267,2568,1,1.000471353,0.828861671,1.207097902,1,DB0903710076476_,0,0.000471242,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,pembrolizumab,DB09037
,2701479,DB14513,10076476,56,7121,19,3545,0.175613443,1.467219935,0.85701716,2.619114768,0.31810806,DB1451310076476_,1.145364143,0.383369409,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium,DB14513
,2702548,DB00193,10076476,124,19196,41,8661,0.091397842,1.364601633,0.950613685,1.994831146,0.197506266,DB0019310076476_,1.621984966,0.310862542,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,2702549,DB00273,10076476,78,8403,27,2166,0.183312213,0.744677373,0.473869811,1.20342742,0.328016026,DB0027310076476_,1.114692811,-0.294804211,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,topiramate,DB00273
,2702550,DB00497,10076476,106,19161,68,16307,0.079195026,1.326626805,0.968479884,1.827692655,0.177055479,DB0049710076476_,1.731292155,0.282639484,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,2702606,DB09029,10077040,59,11285,39,7231,0.917433892,0.969341194,0.635329261,1.493792017,0.963349796,DB0902910077040_,0.037338698,-0.031138619,NA,10077040,Wrong technique in device usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,2702817,DB09035,10076476,193,4533,194,6496,0.000634536,1.425586795,1.157613507,1.755683562,0.003776045,DB0903510076476_,5.579078113,0.354583515,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,nivolumab,DB09035
,2702854,DB00115,10076476,92,18333,50,10422,0.861190065,1.046010189,0.732768859,1.508412818,0.934992198,DB0011510076476_,0.067217094,0.044983106,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,2702855,DB00555,10076476,58,6989,27,3459,0.907922169,1.063155719,0.661187928,1.749515188,0.958771936,DB0055510076476_,0.042102046,0.061241579,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,lamotrigine,DB00555
,2702856,DB00557,10076476,49,5938,32,3035,0.289805535,0.782688064,0.49009407,1.265664242,0.454982141,DB0055710076476_,0.787497112,-0.245021048,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxyzine,DB00557
,2702857,DB01069,10076476,51,6649,14,2381,0.479555579,1.304449312,0.709603996,2.55692459,0.64453231,DB0106910076476_,0.439230325,0.265780969,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,promethazine,DB01069
,2704627,DB00404,10079487,61,19831,21,9841,0.159638552,1.441451865,0.864757852,2.49382455,0.296974369,DB0040410079487_,1.214109443,0.365650845,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,alprazolam,DB00404
,2704628,DB00695,10079487,71,27978,24,20504,0.00078952,2.167997414,1.347466911,3.603469588,0.004524697,DB0069510079487_,5.398204712,0.773803891,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,furosemide,DB00695
,2704631,DB05316,10079487,24,4332,34,6961,0.685204748,1.134251053,0.642598178,1.972799378,0.809887557,DB0531610079487_,0.210859859,0.125972568,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,pimavanserin,DB05316
,2706748,DB09140,10078798,57,3684,19,1779,0.176217599,1.448606678,0.845911221,2.586972928,0.318999971,DB0914010078798_,1.142564267,0.370602183,NA,10078798,Oxygen therapy,10042613,Surgical and medical procedures,Surg,oxygen,DB09140
,2706932,DB00203,10079487,49,13829,16,8922,0.015565868,1.975761686,1.103703142,3.724459695,0.050759736,DB0020310079487_,2.980651841,0.680953988,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,sildenafil,DB00203
,2706934,DB08932,10079487,82,19361,27,6570,1,1.030607931,0.659310765,1.658013213,1,DB0893210079487_,0,0.030148852,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,macitentan,DB08932
,2707415,DB06589,10076476,85,1945,81,2572,0.038425825,1.387550299,1.005270767,1.916405066,0.102499029,DB0658910076476_,2.277901952,0.327539817,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,pazopanib,DB06589
,2708874,DB00203,10076476,55,13823,49,8889,0.107081365,0.721827138,0.481676135,1.0843773,0.221746922,DB0020310076476_,1.506218537,-0.32596959,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,2708875,DB00213,10076476,126,18769,80,13341,0.478259861,1.119538537,0.83850701,1.502046337,0.643564157,DB0021310076476_,0.440733557,0.11291658,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,2708876,DB00331,10076476,185,24761,88,20664,1.02574306349184e-05,1.754401387,1.352959336,2.289461546,0.000110999,DB0033110076476_,9.105989391,0.562127709,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,2708877,DB00678,10076476,104,15495,69,10655,0.876695358,1.036446718,0.756408748,1.427746373,0.947355032,DB0067810076476_,0.054081354,0.035798246,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,2708878,DB00788,10076476,71,9285,28,5033,0.169998934,1.374473009,0.874791528,2.214503115,0.310893405,DB0078810076476_,1.168305174,0.318070392,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,2708879,DB01050,10076476,111,17997,65,9306,0.426002019,0.88303309,0.643706982,1.219804561,0.594755567,DB0105010076476_,0.519604769,-0.124392604,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,2708880,DB01068,10076476,95,13668,39,6801,0.357492563,1.212031351,0.825630904,1.809902658,0.527185746,DB0106810076476_,0.640202333,0.192297754,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,2708881,DB01104,10076476,109,15354,58,7228,0.454497983,0.884709129,0.636757754,1.240138954,0.622018093,DB0110410076476_,0.474786099,-0.122496356,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,2708882,DB01156,10076476,88,13534,32,6296,0.278929091,1.279242238,0.843729729,1.984294064,0.442812459,DB0115610076476_,0.814608941,0.246267901,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,2708894,DB00877,10076476,124,984,231,1200,0.000343252,0.654739783,0.513638654,0.831756234,0.002257854,DB0087710076476_,6.093340614,-0.4235174,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,sirolimus,DB00877
,2708896,DB01015,10076476,79,9808,104,9277,0.030926579,0.718506339,0.528612154,0.973425849,0.086770042,DB0101510076476_,2.444493857,-0.330580751,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,sulfamethoxazole,DB01015
,2709037,DB00065,10076476,155,9309,130,4827,8.76018733891063e-05,0.618248867,0.485209879,0.788846486,0.000712774,DB0006510076476_,7.246346664,-0.480864206,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,infliximab,DB00065
,2709053,DB09303,10079487,34,26197,24,18935,1,1.023957524,0.589432982,1.80534845,1,DB0930310079487_,0,0.023675046,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,evolocumab,DB09303
,2709689,DB00091,10076476,139,5371,108,2562,0.000245288,0.613952509,0.471838734,0.800605711,0.001707082,DB0009110076476_,6.372970022,-0.4878377,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclosporine,DB00091
,2709691,DB00582,10076476,30,1100,57,1517,0.184904579,0.7259215,0.447134184,1.157501238,0.330020836,DB0058210076476_,1.108599487,-0.320313397,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,voriconazole,DB00582
,2709692,DB00860,10076476,47,1836,31,1465,0.489218049,1.209697212,0.74829703,1.980487905,0.652604605,DB0086010076476_,0.426783838,0.19037009,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisolone,DB00860
,2709795,DB09073,10076476,272,19988,87,703,8.60138249559732e-46,0.10998952,0.085020055,0.143350126,4.22593156816403e-43,DB0907310076476_,97.56991927,-2.207370193,male,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,palbociclib,DB09073
,2710542,DB14185,10078575,22,542,32,601,0.402934149,0.762511187,0.416609017,1.372559287,0.572709896,DB1418510078575_,0.557375981,-0.271138099,NA,10078575,Therapeutic response shortened,10018065,General disorders and administration site conditions,Genrl,aripiprazole lauroxil,DB14185
,2710949,DB01118,10076476,33,3030,82,4627,0.020645155,0.614586572,0.396253025,0.933810405,0.063361436,DB0111810076476_,2.758899868,-0.486805478,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,amiodarone,DB01118
,2711326,DB00682,10079487,32,19427,33,16331,0.455242659,0.815167967,0.485073363,1.36830826,0.622777833,DB0068210079487_,0.473565432,-0.204361092,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,warfarin,DB00682
,2711374,DB00005,10078575,117,127965,46,42373,0.319569194,0.842192358,0.593902886,1.212123008,0.487772272,DB0000510078575_,0.717906638,-0.171746837,NA,10078575,Therapeutic response shortened,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,2711722,DB00853,10076476,91,1730,91,2175,0.147046737,1.257146952,0.923034994,1.71220386,0.279823343,DB0085310076476_,1.273596792,0.228844829,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,temozolomide,DB00853
,2712344,DB00490,10076476,38,4032,12,1564,0.635707757,1.228284657,0.626319276,2.589010127,0.77357991,DB0049010076476_,0.256726304,0.205618609,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,buspirone,DB00490
,2712345,DB00927,10076476,63,7434,34,4982,0.349636402,1.241742618,0.804387764,1.946882579,0.519234668,DB0092710076476_,0.655399345,0.21651573,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,famotidine,DB00927
,2712346,DB01076,10076476,147,25600,145,25438,0.953284107,1.007377965,0.794807606,1.276862825,0.991240491,DB0107610076476_,0.008798099,0.00735088,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,2712446,DB00005,10076476,57,128025,32,42387,0.019445644,0.58974569,0.3759722,0.939905089,0.060474297,DB0000510076476_,2.805536847,-0.52806387,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,2712447,DB00051,10076476,43,25688,21,11399,0.68688914,0.908633232,0.52723997,1.612636922,0.811163674,DB0005110076476_,0.209285428,-0.095813751,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,2712448,DB00158,10076476,93,16722,43,8061,0.854876607,1.042586692,0.718149519,1.535043667,0.929630334,DB0015810076476_,0.072968262,0.041704829,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,2713848,DB09128,10076476,38,1326,23,547,0.155402094,0.681697276,0.39161041,1.210728042,0.291361607,DB0912810076476_,1.233190149,-0.383169597,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,brexpiprazole,DB09128
,2713852,DB00281,10076476,125,11333,50,5621,0.225813778,1.239913003,0.884991741,1.760465911,0.380652546,DB0028110076476_,0.965868274,0.215041218,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,lidocaine,DB00281
,2713853,DB00571,10076476,66,5057,33,2576,1,1.018783789,0.659150845,1.602171267,1,DB0057110076476_,0,0.018609552,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,propranolol,DB00571
,2714063,DB00073,10076476,152,7254,143,6264,0.479219657,0.91787729,0.723762667,1.164522365,0.64436088,DB0007310076476_,0.439496336,-0.085691568,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,rituximab,DB00073
,2714064,DB00531,10076476,175,7077,173,6343,0.384425296,0.906652322,0.728529484,1.12844274,0.554482888,DB0053110076476_,0.589719334,-0.09799623,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclophosphamide,DB00531
,2714065,DB00541,10076476,103,3031,94,4203,0.004256275,1.519318665,1.132882926,2.039661441,0.017972079,DB0054110076476_,4.018935893,0.418261988,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,vincristine,DB00541
,2714066,DB00773,10076476,83,2240,90,2737,0.438534678,1.126812696,0.821469037,1.544185685,0.606918145,DB0077310076476_,0.499361348,0.119393024,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,etoposide,DB00773
,2714067,DB00997,10076476,112,5219,108,3406,0.005146197,0.676835454,0.513038134,0.893212274,0.020936046,DB0099710076476_,3.866282932,-0.390327087,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,doxorubicin,DB00997
,2714098,DB01234,10076476,136,31489,115,32773,0.113620027,1.230824301,0.952634668,1.59261094,0.231556689,DB0123410076476_,1.462930558,0.207684108,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,2714473,DB00005,10079487,202,127880,52,42367,0.110145749,1.286970987,0.944462672,1.781484561,0.226274406,DB0000510079487_,1.486006831,0.252291385,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,etanercept,DB00005
,2714476,DB00381,10079487,62,29298,34,22853,0.100470329,1.422376437,0.921275202,2.230039951,0.211529571,DB0038110079487_,1.553390475,0.35232902,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,amlodipine,DB00381
,2715009,DB01452,10010144,68,550,38,1135,1.56576152133475e-10,3.689859493,2.411009824,5.718715263,4.94663961397642e-09,DB0145210010144_,19.12455736,1.30558838,female,10010144,Completed suicide,10037175,Psychiatric disorders,Psych,diamorphine,DB01452
,2715243,DB08895,10079487,181,27933,42,6604,1,1.018871981,0.724033656,1.463140192,1,DB0889510079487_,0,0.018696115,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,tofacitinib,DB08895
,2715326,DB00958,10076476,124,4470,97,2488,0.015367616,0.711590971,0.538587566,0.9423554,0.050247268,DB0095810076476_,2.990799095,-0.340252012,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,carboplatin,DB00958
,2715327,DB01229,10076476,57,5684,22,2687,0.468724151,1.224748492,0.735299839,2.108726507,0.635136587,DB0122910076476_,0.453915206,0.20273551,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,paclitaxel,DB01229
,2715969,DB00704,10079487,32,4324,32,5162,0.52962202,1.193776608,0.706824251,2.016185444,0.686885814,DB0070410079487_,0.37558721,0.177121902,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,naltrexone,DB00704
,2716313,DB01175,10076476,82,10642,25,4867,0.076161856,1.500035503,0.947143246,2.45391949,0.171742322,DB0117510076476_,1.761760055,0.405488776,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,2716491,DB00704,10020765,30,4326,37,5157,0.902842872,0.966561261,0.575639468,1.61089258,0.957326661,DB0070410020765_,0.043610607,-0.034010598,NA,10020765,Hypersomnia,10029205,Nervous system disorders,Nerv,naltrexone,DB00704
,2716518,DB13867,10076476,31,4519,20,2534,0.661259364,0.869175106,0.478733574,1.612518703,0.793354286,DB1386710076476_,0.23148539,-0.140210671,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone,DB13867
,2716675,DB01136,10076476,49,9835,68,11047,0.266656283,0.80939775,0.548278943,1.187216442,0.428859204,DB0113610076476_,0.846626609,-0.211464827,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,2716676,DB01409,10076476,49,5982,11,3955,0.000500891,2.944828435,1.508459415,6.288436127,0.003095532,DB0140910076476_,5.777795651,1.080050559,female,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,tiotropium,DB01409
,2716677,DB09292,10076476,37,4492,71,8191,0.840455685,0.950256522,0.619624446,1.435997028,0.918426743,DB0929210076476_,0.085093135,-0.051023308,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,sacubitril,DB09292
,2716806,DB01224,10076476,54,8054,52,5865,0.166956221,0.75624142,0.506260055,1.130533825,0.306744785,DB0122410076476_,1.181739195,-0.279394615,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,2718185,DB00215,10076476,58,11045,26,5250,0.906897565,1.060343091,0.656089253,1.756957975,0.95853111,DB0021510076476_,0.04235326,0.058592527,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,2718186,DB01109,10076476,51,4361,29,4241,0.024136464,1.710116697,1.061285364,2.803985313,0.071553258,DB0110910076476_,2.637313243,0.536561612,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,heparin,DB01109
,2718673,DB00836,10079381,22,5513,37,4038,0.002117411,0.435545842,0.244348412,0.759327599,0.010194477,DB0083610079381_,4.585909155,-0.831155225,NA,10079381,Drug use disorder,10037175,Psychiatric disorders,Psych,loperamide,DB00836
,2718796,DB00433,10076476,57,7599,19,6001,0.000707368,2.368947184,1.386540783,4.221963461,0.004130103,DB0043310076476_,5.489453017,0.86244563,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,prochlorperazine,DB00433
,2718905,DB01590,10076476,89,4649,63,2804,0.352738228,0.852079416,0.60793971,1.200299224,0.522497849,DB0159010076476_,0.649134412,-0.160075545,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,everolimus,DB01590
,2719813,DB01452,10070863,173,445,360,813,0.25366783,0.878022487,0.703284011,1.094055021,0.414178893,DB0145210070863_,0.88145729,-0.130083074,NA,10070863,Toxicity to various agents,10022117,"Injury, poisoning and procedural complications",Inj&P,diamorphine,DB01452
,2720368,DB00697,10076476,44,6052,14,1792,0.756217246,0.930601776,0.49913466,1.843127353,0.863361434,DB0069710076476_,0.146921864,-0.071923831,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,tizanidine,DB00697
,2720370,DB01267,10076476,104,2748,98,3617,0.02093486,1.396724909,1.044752413,1.868416947,0.064078347,DB0126710076476_,2.747648778,0.334130146,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,paliperidone,DB01267
,2720380,DB00341,10076476,116,11289,44,5024,0.390523648,1.173252711,0.821138565,1.702891294,0.560403673,DB0034110076476_,0.579097911,0.159779986,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,2720384,DB00563,10076476,274,46372,178,15170,7.09225972290641e-12,0.503553741,0.415093556,0.61218251,2.78125056955695e-10,DB0056310076476_,22.00295026,-0.686064837,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,2720385,DB00588,10076476,93,16431,46,8422,0.928432601,1.036278085,0.719566834,1.510866512,0.970197027,DB0058810076476_,0.030256108,0.03563553,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,2720387,DB00668,10076476,46,10045,35,4268,0.01050047,0.558472366,0.351453158,0.8944281,0.037010372,DB0066810076476_,3.296557081,-0.582550141,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,epinephrine,DB00668
,2720389,DB01611,10076476,105,11808,42,2319,0.000297277,0.490998003,0.339213837,0.722129315,0.002002289,DB0161110076476_,6.213464107,-0.711315218,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxychloroquine,DB01611
,2720390,DB14512,10076476,62,4782,26,2386,0.496261869,1.189766895,0.739282297,1.965348934,0.658534089,DB1451210076476_,0.417738992,0.173757402,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,mometasone furoate,DB14512
,2720464,DB00005,10077040,48,128034,14,42405,0.769760251,1.135544099,0.615723668,2.230489019,0.873907707,DB0000510077040_,0.134780507,0.127111918,NA,10077040,Wrong technique in device usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,2720874,DB11988,10016173,71,3073,46,1180,0.008760212,0.592757626,0.400707455,0.884258432,0.03202979,DB1198810016173_,3.441088859,-0.522969689,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,ocrelizumab,DB11988
,2721898,DB00230,10079487,176,19498,51,8600,0.007368648,1.522114889,1.107493952,2.124203506,0.027892413,DB0023010079487_,3.57940058,0.420100742,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,pregabalin,DB00230
,2722037,DB06186,10076476,46,2163,70,3576,0.699029956,1.086410741,0.72921568,1.605217468,0.819056632,DB0618610076476_,0.19960205,0.082879365,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,ipilimumab,DB06186
,2722095,DB11988,10019974,104,3040,25,1201,0.028212647,1.643311566,1.047598765,2.668746176,0.080719432,DB1198810019974_,2.516775935,0.496713453,NA,10019974,Herpes zoster,10021881,Infections and infestations,Infec,ocrelizumab,DB11988
,2722320,DB00186,10076476,134,16767,82,9926,0.832205165,0.967385433,0.72866138,1.290940514,0.912502618,DB0018610076476_,0.091564325,-0.033158276,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,2722698,DB00515,10076476,34,1836,51,2100,0.229163244,0.762579318,0.476800939,1.206078006,0.384891749,DB0051510076476_,0.954793156,-0.271048753,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,cisplatin,DB00515
,2723886,DB00620,10076476,64,4764,42,3090,1,0.988363861,0.657509231,1.499502224,1,DB0062010076476_,0,-0.011704369,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,triamcinolone,DB00620
,2724322,DB01238,10076476,111,5139,106,3396,0.007660492,0.692046798,0.523547737,0.915157164,0.028769259,DB0123810076476_,3.548447859,-0.368101699,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole,DB01238
,2724404,DB00734,10076476,37,4013,150,4752,2.9622508684767e-13,0.292138054,0.197606498,0.422156501,1.43261755433137e-11,DB0073410076476_,24.96893279,-1.2305288,male,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,2724586,DB00959,10076476,182,7896,128,4874,0.261871999,0.877699412,0.694200211,1.112386848,0.423535903,DB0095910076476_,0.85911699,-0.130451099,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,methylprednisolone,DB00959
,2724590,DB00688,10076476,324,6166,347,5031,0.000681649,0.761867992,0.649739658,0.893154439,0.00400348,DB0068810076476_,5.520591175,-0.271981977,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,mycophenolate mofetil,DB00688
,2724638,DB00188,10076476,28,7858,35,8793,0.70561164,0.89520834,0.524089062,1.516175353,0.823597413,DB0018810076476_,0.194073445,-0.110698806,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,bortezomib,DB00188
,2724757,DB05219,10076476,47,1171,29,595,0.457950539,0.823595918,0.501851281,1.371967904,0.625261923,DB0521910076476_,0.46958464,-0.19407526,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,crisaborole,DB05219
,2725534,DB06210,10076476,42,1418,37,1024,0.418266742,0.819801262,0.510290504,1.321860496,0.587246819,DB0621010076476_,0.532310072,-0.198693331,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,eltrombopag,DB06210
,2726394,DB00316,10079487,159,65315,52,36901,0.000421398,1.727494106,1.255459767,2.411149296,0.002674179,DB0031610079487_,5.924112775,0.546671865,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,acetaminophen,DB00316
,2726395,DB00451,10079487,138,47133,19,15400,0.000126957,2.373222684,1.462751861,4.062877341,0.000978181,DB0045110079487_,6.929815673,0.864248814,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,levothyroxine,DB00451
,2726400,DB01611,10079487,54,11859,9,2352,0.735568415,1.189968087,0.581613204,2.745335115,0.847238699,DB0161110079487_,0.165772807,0.173926489,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,hydroxychloroquine,DB01611
,2727374,DB00399,10076476,36,6956,17,4981,0.165112007,1.51633675,0.828877989,2.882304223,0.304292313,DB0039910076476_,1.189766485,0.416297393,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,zoledronic acid,DB00399
,2728703,DB01452,10007617,111,507,139,1034,0.000554496,1.628213756,1.228808216,2.154207654,0.003362926,DB0145210007617_,5.694943719,0.487483559,NA,10007617,Cardio-respiratory arrest,10007541,Cardiac disorders,Card,diamorphine,DB01452
,2729897,DB09153,10020597,92,7707,105,5594,0.001736221,0.636003837,0.474371614,0.851452505,0.008650664,DB0915310020597_,4.750119228,-0.452550682,NA,10020597,Hyperchloraemia,10027433,Metabolism and nutrition disorders,Metab,sodium chloride,DB09153
,2731364,DB12159,10010741,227,2846,245,1823,9.21668463146395e-08,0.593571075,0.488520766,0.720923575,1.67947912218494e-06,DB1215910010741_,13.29702686,-0.521598316,NA,10010741,Conjunctivitis,10021881,Infections and infestations,Infec,dupilumab,DB12159
,2731378,DB00398,10076476,45,682,62,1476,0.026052365,1.570493936,1.033807153,2.370192187,0.075834597,DB0039810076476_,2.579200661,0.451390179,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,sorafenib,DB00398
,2731507,DB06791,10022081,46,733,24,514,0.263650509,1.343725632,0.791845613,2.332763987,0.425504759,DB0679110022081_,0.854479146,0.295446078,NA,10022081,Injection site mass,10018065,General disorders and administration site conditions,Genrl,lanreotide,DB06791
,2732043,DB00186,10079487,45,16856,12,9996,0.012856991,2.223774885,1.156231627,4.620474948,0.04349045,DB0018610079487_,3.135213898,0.799206151,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,lorazepam,DB00186
,2733003,DB00471,10076476,151,14038,56,5409,0.876108178,1.03899505,0.75849168,1.440755766,0.946934637,DB0047110076476_,0.054525209,0.038253948,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,2734962,DB01006,10076476,72,5875,6,171,0.024707559,0.3493782,0.149967476,0.997145506,0.072855875,DB0100610076476_,2.619272108,-1.051600277,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,letrozole,DB01006
,2735364,DB00115,10079487,62,18363,22,10450,0.068222209,1.603743468,0.971394294,2.741635638,0.15809052,DB0011510079487_,1.844587499,0.472340564,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,cyanocobalamin,DB00115
,2735365,DB00169,10079487,111,38580,44,18131,0.388431257,1.18555952,0.82868943,1.722403906,0.558437652,DB0016910079487_,0.582612302,0.170214832,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,cholecalciferol,DB00169
,2735366,DB00476,10079487,71,17186,18,6159,0.227655696,1.413528421,0.83270606,2.522158077,0.382922503,DB0047610079487_,0.959922652,0.346089005,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,duloxetine,DB00476
,2735369,DB00996,10079487,110,38843,48,22377,0.116128844,1.320196656,0.932034804,1.894640771,0.235337626,DB0099610079487_,1.44673409,0.277780707,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,gabapentin,DB00996
,2735370,DB01050,10079487,50,18058,14,9357,0.046760015,1.850546916,1.00654997,3.626775013,0.119005324,DB0105010079487_,2.128587051,0.615481226,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,ibuprofen,DB01050
,2735371,DB01076,10079487,64,25683,31,25552,0.000919899,2.053947143,1.317294225,3.264700636,0.00514568,DB0107610079487_,5.269597757,0.719763377,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,atorvastatin,DB01076
,2735492,DB00736,10076476,45,10546,25,5528,0.802147474,0.943527692,0.565655056,1.607414579,0.892951095,DB0073610076476_,0.113223464,-0.058129564,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,esomeprazole,DB00736
,2735493,DB06724,10076476,56,7873,21,3898,0.331072128,1.320301488,0.785526278,2.299177847,0.499790786,DB0672410076476_,0.693565697,0.277860111,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium carbonate,DB06724
,2735599,DB00264,10079487,62,29545,38,24854,0.132268667,1.37251514,0.901749319,2.113626248,0.259018954,DB0026410079487_,1.350854038,0.316644925,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,metoprolol,DB00264
,2735600,DB00678,10079487,48,15551,14,10710,0.004030574,2.36117801,1.279663161,4.63949069,0.017190271,DB0067810079487_,4.063411708,0.859160651,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,losartan,DB00678
,2737268,DB00758,10076476,37,8263,44,10030,1,1.020737121,0.640299764,1.619038206,1,DB0075810076476_,0,0.020525034,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,2737647,DB08895,10076476,344,27770,148,6498,4.12875602899712e-09,0.543896524,0.446372782,0.66527453,1.01046882888444e-07,DB0889510076476_,16.10768124,-0.608996264,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,2738015,DB00761,10076476,70,15237,36,8589,0.686346005,1.096077757,0.722508777,1.68859757,0.810800841,DB0076110076476_,0.209732827,0.091738132,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,2738111,DB00370,10076476,71,4470,55,3608,0.856968319,1.041970773,0.720285086,1.514100358,0.931379461,DB0037010076476_,0.0710885,0.041113894,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,mirtazapine,DB00370
,2738112,DB00864,10076476,316,6553,427,7965,0.173522701,0.899534412,0.772386295,1.0467288,0.315509405,DB0086410076476_,1.153566789,-0.105877969,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,tacrolimus,DB00864
,2740155,DB00425,10076476,65,12630,41,7443,0.76261826,0.934277682,0.621773808,1.418372134,0.868521505,DB0042510076476_,0.140962932,-0.06798158,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,2740416,DB00193,10079487,62,19258,18,8684,0.115233636,1.553179221,0.906269142,2.791685938,0.233992549,DB0019310079487_,1.452466006,0.440303941,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,tramadol,DB00193
,2740422,DB00497,10079487,57,19210,39,16336,0.306954976,1.242869596,0.812245557,1.919510894,0.474007082,DB0049710079487_,0.746533016,0.217422896,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,oxycodone,DB00497
,2740424,DB01068,10079487,38,13725,16,6824,0.665127199,1.180812419,0.642404,2.270108584,0.796177718,DB0106810079487_,0.227932854,0.166202692,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,clonazepam,DB01068
,2741669,DB01377,10076476,33,3763,19,2651,0.572195837,1.223547526,0.673970161,2.282687405,0.72221693,DB0137710076476_,0.325429728,0.201754447,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium oxide,DB01377
,2743095,DB00285,10076476,79,10872,27,3691,1,0.993340378,0.633356222,1.602563311,1,DB0028510076476_,0,-0.006681896,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,2743303,DB00820,10079487,45,11870,12,5804,0.065835259,1.833558218,0.953020577,3.81118146,0.153840938,DB0082010079487_,1.871836081,0.60625846,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,tadalafil,DB00820
,2743305,DB11362,10079487,45,6438,15,2154,1,1.00372766,0.547837136,1.942660931,1,DB1136210079487_,0,0.003720729,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,selexipag,DB11362
,2744066,DB00331,10079487,63,24883,33,20719,0.031161448,1.589597996,1.02691086,2.501908518,0.087265999,DB0033110079487_,2.438794369,0.463481152,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,metformin,DB00331
,2745053,DB08911,10076476,70,1569,72,1676,0.863935365,1.038525741,0.730965465,1.47485685,0.937362382,DB0891110076476_,0.064685324,0.03780215,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,trametinib,DB08911
,2745054,DB08912,10076476,37,1293,46,1488,0.739308953,0.92565193,0.579838953,1.468947475,0.850094527,DB0891210076476_,0.162407728,-0.077257,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,dabrafenib,DB08912
,2745287,DB05679,10076476,42,6889,28,4881,0.903275803,1.06278621,0.642458087,1.783091535,0.957348417,DB0567910076476_,0.043587882,0.060893959,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,ustekinumab,DB05679
,2745385,DB00787,10076476,63,16937,57,17191,0.583420965,1.121834197,0.770964167,1.635453525,0.731448741,DB0078710076476_,0.312728135,0.114965022,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,2748822,DB11988,10035664,108,3036,52,1174,0.209722708,0.803147179,0.567515013,1.148865482,0.360864191,DB1198810035664_,1.019253594,-0.219217295,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,ocrelizumab,DB11988
,2749687,DB00158,10079487,65,16750,18,8086,0.034744474,1.743215315,1.020700099,3.125111873,0.09494812,DB0015810079487_,2.354424639,0.55573129,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,folic acid,DB00158
,2749692,DB01104,10079487,48,15415,15,7271,0.177935945,1.50936171,0.830219524,2.904005189,0.321258805,DB0110410079487_,1.135508233,0.411686853,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,sertraline,DB01104
,2750237,DB00338,10079487,98,33576,23,22249,1.45275946219985e-06,2.823373849,1.777900336,4.662570896,2.00240075846476e-05,DB0033810079487_,10.81857863,1.03793257,female,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,omeprazole,DB00338
,2750247,DB00761,10079487,43,15264,14,8611,0.073659073,1.732671716,0.929155987,3.431540347,0.167593918,DB0076110079487_,1.786211379,0.549664562,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,potassium chloride,DB00761
,2750252,DB00999,10079487,58,21372,25,12214,0.255014926,1.325858629,0.815879527,2.213244711,0.41573277,DB0099910079487_,0.877712604,0.282060271,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,hydrochlorothiazide,DB00999
,2751283,DB00704,10044055,31,4325,27,5167,0.236822543,1.371615231,0.790838825,2.392660285,0.394129451,DB0070410044055_,0.931075867,0.315989046,NA,10044055,Toothache,10017947,Gastrointestinal disorders,Gastr,naltrexone,DB00704
,2751672,DB05316,10019196,20,4336,31,6964,0.886379842,1.036209834,0.55899566,1.879456646,0.952748725,DB0531610019196_,0.048404077,0.035569665,NA,10019196,Head injury,10022117,"Injury, poisoning and procedural complications",Inj&P,pimavanserin,DB05316
,2754229,DB00641,10079487,37,14087,26,12449,0.379905503,1.257592865,0.740794581,2.164291502,0.550031184,DB0064110079487_,0.597780304,0.229199469,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,simvastatin,DB00641
,2755213,DB00047,10077040,44,9241,49,8469,0.351442521,0.822953916,0.534452761,1.263800682,0.521152063,DB0004710077040_,0.651713412,-0.194855075,NA,10077040,Wrong technique in device usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,2755443,DB05316,10013946,33,4323,21,6974,0.001040205,2.534875288,1.421425158,4.616338183,0.005693836,DB0531610013946_,5.168371128,0.93014444,NA,10013946,Dyspepsia,10017947,Gastrointestinal disorders,Gastr,pimavanserin,DB05316
,2755661,DB05316,10043417,62,4294,123,6872,0.194913793,0.806723155,0.583187344,1.10626321,0.342891212,DB0531610043417_,1.070342047,-0.214774725,NA,10043417,Therapeutic response unexpected,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,2757053,DB01181,10076476,33,540,29,891,0.016257544,1.876810758,1.091183962,3.243540499,0.052501322,DB0118110076476_,2.946916923,0.629573931,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,ifosfamide,DB01181
,2757195,DB00563,10078575,39,46607,12,15336,1,1.06940663,0.548404164,2.244218537,1,DB0056310078575_,0,0.067103943,NA,10078575,Therapeutic response shortened,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,2758289,DB00820,10013969,56,11859,9,5807,0.000791393,3.046685188,1.494254234,7.011683389,0.004533953,DB0082010013969_,5.396161066,1.114054176,female,10013969,Dyspnoea at rest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,tadalafil,DB00820
,2758437,DB00741,10076476,61,4033,32,3142,0.074036771,1.48502666,0.950238873,2.360675604,0.168270133,DB0074110076476_,1.782184654,0.395432725,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocortisone,DB00741
,2764646,DB01065,10076476,32,4299,23,3028,1,0.979961015,0.554576028,1.757454293,1,DB0106510076476_,0,-0.020242489,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,melatonin,DB01065
,2767779,DB09153,10076476,55,7744,38,5661,0.833617347,1.058057227,0.686120829,1.646877819,0.913612642,DB0915310076476_,0.090348603,0.056434422,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium chloride,DB09153
,2768160,DB00215,10079487,45,11058,7,5269,0.002712301,3.062970375,1.36991773,8.05710845,0.012449633,DB0021510079487_,4.386064164,1.119385156,female,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,citalopram,DB00215
,2768162,DB00722,10079487,67,25336,40,25992,0.006587905,1.718339411,1.144129885,2.610417006,0.025512058,DB0072210079487_,3.668604089,0.541358366,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,lisinopril,DB00722
,2769165,DB01222,10076476,98,9176,66,5339,0.37105159,0.863963945,0.624699367,1.201291821,0.540681932,DB0122210076476_,0.614924099,-0.146224242,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,budesonide,DB01222
,2773364,DB00207,10076476,95,8985,64,5391,0.510143145,0.890634858,0.640668645,1.245003303,0.670606515,DB0020710076476_,0.399572729,-0.115820747,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,azithromycin,DB00207
,2773365,DB00319,10076476,20,1372,33,1820,0.486260369,0.804011518,0.435177936,1.450525704,0.650136259,DB0031910076476_,0.430573308,-0.218141684,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,piperacillin,DB00319
,2773366,DB00512,10076476,47,4690,67,5031,0.157123094,0.752519989,0.505815713,1.111594186,0.293624865,DB0051210076476_,1.225452297,-0.28432772,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,vancomycin,DB00512
,2773369,DB01225,10076476,44,5000,27,4613,0.096618039,1.503428583,0.90883847,2.52955559,0.205706354,DB0122510076476_,1.581305591,0.407748222,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,enoxaparin,DB01225
,2774124,DB06262,10078932,23,3777,37,4277,0.196311629,0.703943723,0.398586122,1.218955708,0.344577708,DB0626210078932_,1.065435648,-0.351056865,NA,10078932,Supine hypertension,10047065,Vascular disorders,Vasc,droxidopa,DB06262
,2774848,DB01202,10076476,43,6671,53,5665,0.080177263,0.688999354,0.449067336,1.051803313,0.178704262,DB0120210076476_,1.722023005,-0.372514946,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,levetiracetam,DB01202
,2776635,DB00181,10076476,50,9806,23,5848,0.333429773,1.296434873,0.775553714,2.228495403,0.502448063,DB0018110076476_,0.688263001,0.259618092,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,2780214,DB01024,10076476,65,2146,91,2029,0.017958323,0.675408595,0.480622159,0.944636627,0.056755382,DB0102410076476_,2.869004786,-0.392437446,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,mycophenolic acid,DB01024
,2780215,DB01212,10076476,33,1986,29,1912,0.798241618,1.09548492,0.642151946,1.878344018,0.890983946,DB0121210076476_,0.11542887,0.091197115,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,ceftriaxone,DB01212
,2781236,DB00213,10079487,54,18841,26,13395,0.111943718,1.47656891,0.908207104,2.457811798,0.228992618,DB0021310079487_,1.474065513,0.389721092,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,pantoprazole,DB00213
,2784177,DB11089,10076476,69,10106,38,8369,0.050938561,1.503659594,0.996680477,2.299394412,0.126767665,DB1108910076476_,2.06539928,0.407901866,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,2784561,DB00537,10076476,58,7499,34,4264,0.913464625,0.969960616,0.623399866,1.530497824,0.961296669,DB0053710076476_,0.039472209,-0.03049981,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,ciprofloxacin,DB00537
,2784569,DB12159,10013709,114,2959,94,1974,0.148760575,0.809098352,0.606496786,1.081428863,0.282291033,DB1215910013709_,1.264816709,-0.211834796,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,2786182,DB11988,10051792,149,2995,40,1186,0.031351845,1.474986258,1.026825513,2.161142555,0.087677758,DB1198810051792_,2.434087032,0.388648673,NA,10051792,Infusion related reaction,10022117,"Injury, poisoning and procedural complications",Inj&P,ocrelizumab,DB11988
,2786663,DB11988,10046571,273,2871,108,1118,0.905027308,0.984348642,0.776134846,1.255210067,0.957667115,DB1198810046571_,0.043255041,-0.015775134,NA,10046571,Urinary tract infection,10021881,Infections and infestations,Infec,ocrelizumab,DB11988
,2787700,DB00480,10079487,31,67397,25,67637,0.426182309,1.244411083,0.710980903,2.198385834,0.594833505,DB0048010079487_,0.519473736,0.218662392,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,lenalidomide,DB00480
,2787770,DB09303,10068945,290,25941,267,18692,0.00432995,0.782640247,0.659742048,0.928665841,0.018218783,DB0930310068945_,4.005302211,-0.245082143,NA,10068945,Incorrect dose administered by device,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,2789451,DB12159,10015958,35,3038,25,2043,0.894783518,0.941489579,0.545802945,1.646391364,0.955976233,DB1215910015958_,0.045022227,-0.060292,NA,10015958,Eye pain,10015919,Eye disorders,Eye,dupilumab,DB12159
,2789452,DB12159,10023644,36,3037,39,2029,0.043242083,0.616779636,0.379579824,0.99975151,0.112142287,DB1215910023644_,2.187986792,-0.483243473,NA,10023644,Lacrimation increased,10015919,Eye disorders,Eye,dupilumab,DB12159
,2791296,DB11988,10033775,40,3104,13,1213,0.646137135,1.202360206,0.627353587,2.459006719,0.781649463,DB1198810033775_,0.246348896,0.184286463,NA,10033775,Paraesthesia,10029205,Nervous system disorders,Nerv,ocrelizumab,DB11988
,2792555,DB00363,10076476,28,4600,42,6846,1,0.992174429,0.591319555,1.641462833,1,DB0036310076476_,0,-0.007856352,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,clozapine,DB00363
,2792656,DB12159,10022061,97,2976,27,2041,1.60069500806715e-05,2.463469419,1.587393954,3.941392928,0.000163873,DB1215910022061_,8.716421779,0.901570689,NA,10022061,Injection site erythema,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,2792657,DB12159,10022086,80,2993,38,2030,0.086928648,1.427797015,0.954507331,2.169012367,0.189911443,DB1215910022086_,1.661197405,0.356132707,NA,10022086,Injection site pain,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,2792658,DB12159,10022093,46,3027,12,2056,0.001841812,2.603239283,1.352988834,5.412127592,0.009090609,DB1215910022093_,4.7005134,0.956756547,NA,10022093,Injection site pruritus,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,2792659,DB12159,10022094,49,3024,6,2062,2.42161074085938e-06,5.56732008,2.376513566,15.9371185,3.13017154283201e-05,DB1215910022094_,10.37183766,1.716913804,female,10022094,Injection site rash,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,2792660,DB12159,10053425,54,3019,11,2057,6.26646070627085e-05,3.344140547,1.723619233,7.109691418,0.000534612,DB1215910053425_,7.533969536,1.207209724,female,10053425,Injection site swelling,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,2795285,DB00295,10076476,64,14599,41,9561,1,1.022295438,0.679484251,1.553415544,1,DB0029510076476_,0,0.022050528,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,2795286,DB00950,10076476,41,4677,17,2039,1,1.051432679,0.582709729,1.978820141,1,DB0095010076476_,0,0.05015369,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,fexofenadine,DB00950
,2795521,DB00635,10079487,117,32936,20,23774,6.80411146272248e-12,4.222557464,2.612484145,7.169456878,2.68537642338829e-10,DB0063510079487_,22.03803002,1.440440979,female,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,prednisone,DB00635
,2797984,DB00575,10076476,43,5201,28,3801,0.717796263,1.122355352,0.680028799,1.879697538,0.833360193,DB0057510076476_,0.182289326,0.11542947,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,clonidine,DB00575
,2797985,DB14500,10076476,46,7763,16,4057,0.180535555,1.502447743,0.833648699,2.846851816,0.324492414,DB1450010076476_,1.125493122,0.407095607,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium,DB14500
,2801688,DB00586,10076476,73,7036,22,2783,0.303417947,1.312401551,0.803503249,2.225415596,0.469939351,DB0058610076476_,0.755151633,0.271858704,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,diclofenac,DB00586
,2805524,DB08932,10078798,69,19374,24,6573,0.90518292,0.975398597,0.604560602,1.624759955,0.957743104,DB0893210078798_,0.043175696,-0.024909075,NA,10078798,Oxygen therapy,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,2809669,DB00327,10076476,47,6091,21,4241,0.107297745,1.558260441,0.911776752,2.748612464,0.222107515,DB0032710076476_,1.504593712,0.443570097,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,hydromorphone,DB00327
,2809670,DB00813,10076476,67,10505,43,10125,0.044175059,1.501740742,1.007839703,2.259079944,0.113943518,DB0081310076476_,2.172052407,0.40662493,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,2809821,DB00334,10076476,28,2821,32,2780,0.605108503,0.86230623,0.498764461,1.48284803,0.748273008,DB0033410076476_,0.289987383,-0.148144816,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,olanzapine,DB00334
,2809833,DB00916,10076476,44,5279,29,2402,0.128792573,0.69038663,0.421234131,1.147258958,0.253914328,DB0091610076476_,1.370758361,-0.370503505,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,metronidazole,DB00916
,2810256,DB05316,10057362,224,4132,313,6682,0.111520372,1.157289572,0.966147308,1.384566408,0.228313746,DB0531610057362_,1.477034516,0.146080695,NA,10057362,Underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,pimavanserin,DB05316
,2822269,DB08932,10057374,73,19370,16,6581,0.114040493,1.550045771,0.892841871,2.855639053,0.232240985,DB0893210057374_,1.459979716,0.43828446,NA,10057374,Rehabilitation therapy,10042613,Surgical and medical procedures,Surg,macitentan,DB08932
,2825929,DB12159,10037844,223,2850,142,1926,0.618406494,1.061273803,0.848958673,1.329947975,0.759269202,DB1215910037844_,0.275398885,0.059469888,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,dupilumab,DB12159
,2826888,DB12159,10011224,30,3043,20,2048,1,1.009528449,0.552943734,1.881137806,1,DB1215910011224_,0,0.00948334,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dupilumab,DB12159
,2827556,DB00795,10077692,53,4516,10,1493,0.107847242,1.751967968,0.8792884,3.872751917,0.222841344,DB0079510077692_,1.501295221,0.560739709,NA,10077692,Liver function test increased,10022891,Investigations,Inv,sulfasalazine,DB00795
,2828435,DB00681,10076476,17,396,34,608,0.462654304,0.767863944,0.396597961,1.435567085,0.62988467,DB0068110076476_,0.46221854,-0.264142718,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,amphotericin b,DB00681
,2830134,DB12159,10015967,44,3029,24,2044,0.455998833,1.237092879,0.733398535,2.134054804,0.623389239,DB1215910015967_,0.472584173,0.212764174,NA,10015967,Eye swelling,10015919,Eye disorders,Eye,dupilumab,DB12159
,2831075,DB05676,10079487,142,46987,45,25284,0.001582087,1.698012233,1.206064852,2.4314295,0.008024152,DB0567610079487_,4.825299284,0.529458292,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,apremilast,DB05676
,2833149,DB00656,10076476,100,11913,48,6571,0.490391802,1.149107104,0.805526655,1.659134686,0.653631932,DB0065610076476_,0.425210881,0.13898521,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,2840572,DB00028,10076476,213,13245,76,5539,0.268811435,1.172030114,0.896148174,1.546751187,0.431264186,DB0002810076476_,0.841034416,0.158737386,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,human immunoglobulin g,DB00028
,2841397,DB00051,10078504,179,25552,29,11391,2.47874093267856e-08,2.751581181,1.850039825,4.2293,5.09610523390347e-07,DB0005110078504_,14.48961908,1.012175721,female,10078504,Contraindicated product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,2854725,DB00588,10079487,42,16482,12,8456,0.083431518,1.795617605,0.927464471,3.748659253,0.184153962,DB0058810079487_,1.691983122,0.585349032,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,fluticasone propionate,DB00588
,2854787,DB11988,10040047,61,3083,42,1184,0.005262782,0.557877256,0.368146608,0.852309068,0.021304826,DB1198810040047_,3.84882165,-0.583616313,NA,10040047,Sepsis,10021881,Infections and infestations,Infec,ocrelizumab,DB11988
,2860591,DB00051,10078575,54,25677,27,11393,0.630212606,0.887418644,0.548981301,1.466064756,0.769165758,DB0005110078575_,0.262448783,-0.11943843,NA,10078575,Therapeutic response shortened,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,2862454,DB01137,10076476,49,7723,43,5550,0.342038284,0.818924342,0.531690151,1.265358497,0.511272786,DB0113710076476_,0.670852004,-0.199763578,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,levofloxacin,DB01137
,2865394,DB00080,10076476,41,599,63,850,0.757406504,0.923526069,0.598827546,1.411370954,0.86438411,DB0008010076476_,0.145738037,-0.079556251,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,daptomycin,DB00080
,2865858,DB11988,10011224,91,3053,13,1213,0.000223403,2.780587182,1.540098103,5.441897548,0.001580873,DB1198810011224_,6.449777766,1.022662122,female,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ocrelizumab,DB11988
,2865859,DB11988,10043521,148,2996,33,1193,0.002271195,1.785647758,1.209414612,2.705930025,0.010791461,DB1198810043521_,4.529000144,0.579781239,NA,10043521,Throat irritation,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ocrelizumab,DB11988
,2868348,DB01190,10076476,41,4893,14,2271,0.383379937,1.359232054,0.724039218,2.705359289,0.55342619,DB0119010076476_,0.591626887,0.306919874,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,clindamycin,DB01190
,2873097,DB12159,10064355,58,3015,33,2035,0.452721175,1.186226343,0.757682696,1.885173825,0.620345423,DB1215910064355_,0.477478822,0.170777128,NA,10064355,Incorrect dose administered,10022117,"Injury, poisoning and procedural complications",Inj&P,dupilumab,DB12159
,2880707,DB12159,10047513,60,3013,37,2031,0.754026232,1.093101418,0.710791842,1.70083839,0.861702116,DB1215910047513_,0.148845642,0.089018993,NA,10047513,Vision blurred,10015919,Eye disorders,Eye,dupilumab,DB12159
,2881350,DB00563,10079487,161,46485,35,15313,0.0250208,1.515275058,1.045484034,2.252475823,0.073503405,DB0056310079487_,2.610423548,0.415596979,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,methotrexate,DB00563
,2896683,DB00987,10076476,23,2081,49,2879,0.09284985,0.649437643,0.376352835,1.09046044,0.199816465,DB0098710076476_,1.610356007,-0.431648456,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,cytarabine,DB00987
,2898695,DB01202,10048723,43,6671,34,5684,0.818833494,1.077607125,0.670259994,1.7449259,0.903336849,DB0120210048723_,0.101659762,0.074742958,NA,10048723,Multiple-drug resistance,10018065,General disorders and administration site conditions,Genrl,levetiracetam,DB01202
,2907957,DB00993,10076476,61,3188,55,1564,0.001369571,0.544157095,0.369738711,0.802484516,0.007137031,DB0099310076476_,4.94245844,-0.608517295,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,azathioprine,DB00993
,2910441,DB08904,10079487,43,11567,14,3545,0.875551504,0.941314824,0.504441684,1.865158089,0.946510165,DB0890410079487_,0.054973569,-0.060477633,NA,10079487,Loss of personal independence in daily activities,10041244,Social circumstances,SocCi,certolizumab pegol,DB08904
,2911321,DB11988,10016825,47,3097,17,1209,0.888845504,1.079260422,0.605497051,2.013283564,0.953896257,DB1198810016825_,0.047200359,0.076276012,NA,10016825,Flushing,10047065,Vascular disorders,Vasc,ocrelizumab,DB11988
,2911322,DB11988,10019211,142,3002,31,1195,0.002391893,1.823189178,1.221082762,2.799457054,0.011258106,DB1198810019211_,4.486666835,0.600587263,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,ocrelizumab,DB11988
,2911326,DB11988,10068319,44,3100,10,1216,0.128865067,1.725765488,0.852254072,3.858482548,0.253962008,DB1198810068319_,1.370570599,0.545670713,NA,10068319,Oropharyngeal pain,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,ocrelizumab,DB11988
,2912222,DB11988,10013573,67,3077,20,1206,0.335314056,1.312891727,0.782808558,2.2950524,0.504549902,DB1198810013573_,0.68408853,0.272232129,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,ocrelizumab,DB11988
,2912276,DB12159,10001760,84,2989,28,2040,0.000851894,2.047236872,1.315168767,3.274533989,0.00482275,DB1215910001760_,5.334411036,0.716491017,NA,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,dupilumab,DB12159
,2915123,DB00005,10076503,37,128045,15,42404,0.521554172,0.816858063,0.43757523,1.602318079,0.680347999,DB0000510076503_,0.385150848,-0.202289929,NA,10076503,Inability to afford medication,10041244,Social circumstances,SocCi,etanercept,DB00005
,2915203,DB11988,10028372,54,3090,42,1184,0.001153535,0.492722455,0.321208825,0.760401463,0.006199277,DB1198810028372_,5.083322534,-0.707809234,NA,10028372,Muscular weakness,10028395,Musculoskeletal and connective tissue disorders,Musc,ocrelizumab,DB11988
,2920698,DB09037,10077665,30,2496,62,2773,0.005884136,0.53763153,0.33441951,0.847403564,0.023310402,DB0903710077665_,3.758855567,-0.620581842,NA,10077665,Immune-mediated adverse reaction,10021428,Immune system disorders,Immun,pembrolizumab,DB09037
,2932282,DB01216,10076476,10,226,46,7069,9.34394511240636e-06,6.795289187,3.018246981,13.87384613,0.0001024,DB0121610076476_,9.186627114,1.916229605,female,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,finasteride,DB01216
,2938304,DB12159,10012431,55,3018,41,2027,0.674503497,0.900996142,0.5879143,1.390534805,0.802613206,DB1215910012431_,0.219882367,-0.104254304,NA,10012431,Dermatitis,10040785,Skin and subcutaneous tissue disorders,Skin,dupilumab,DB12159
,2939336,DB05316,10073085,222,4134,339,6656,0.562799946,1.054363406,0.882161009,1.258308562,0.714992585,DB0531610073085_,0.335483107,0.052937178,NA,10073085,Prescribed underdose,10022117,"Injury, poisoning and procedural complications",Inj&P,pimavanserin,DB05316
,2942526,DB01263,10076476,30,594,60,805,0.098500863,0.677781607,0.41649169,1.082792803,0.208638155,DB0126310076476_,1.567153842,-0.388930157,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,posaconazole,DB01263
,2943639,DB11988,10020751,40,3104,13,1213,0.646137135,1.202360206,0.627353587,2.459006719,0.781649463,DB1198810020751_,0.246348896,0.184286463,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,ocrelizumab,DB11988
,2947055,DB11988,10037087,159,2985,74,1152,0.202830786,0.829288431,0.619931071,1.117510182,0.352361602,DB1198810037087_,1.043097353,-0.187187257,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,ocrelizumab,DB11988
,2947181,DB12159,10030041,77,2996,89,1979,0.000504252,0.57156735,0.413451374,0.78867419,0.003111331,DB1215910030041_,5.772704737,-0.559372956,NA,10030041,Ocular hyperaemia,10015919,Eye disorders,Eye,dupilumab,DB12159
,2955842,DB06273,10061623,45,5050,7,1403,0.177125455,1.785820202,0.79712368,4.70473426,0.320189568,DB0627310061623_,1.13884206,0.579877806,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,tocilizumab,DB06273
,2956538,DB01610,10076476,28,913,35,1183,0.89806096,1.036583361,0.602575544,1.768391072,0.956338178,DB0161010076476_,0.044643686,0.035930075,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,valganciclovir,DB01610
,2958675,DB01452,10033295,40,578,84,1089,0.625307383,0.897222047,0.591479328,1.342207389,0.764937151,DB0145210033295_,0.267961604,-0.108451904,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,diamorphine,DB01452
,2967232,DB11988,10039906,32,3112,21,1205,0.065330466,0.590114061,0.32844228,1.08139754,0.152994591,DB1198810039906_,1.877352709,-0.527439438,NA,10039906,Seizure,10029205,Nervous system disorders,Nerv,ocrelizumab,DB11988
,2967376,DB01413,10052015,28,1192,53,1606,0.171205607,0.711871616,0.430781511,1.153863109,0.312487978,DB0141310052015_,1.163189281,-0.339857699,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,cefepime,DB01413
,2971816,DB12159,10016256,65,3008,43,2025,1,1.017632532,0.678695494,1.539281726,1,DB1215910016256_,0,0.017478882,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,2971940,DB11581,10029366,26,1727,42,2718,1,0.974278299,0.571206317,1.633309622,1,DB1158110029366_,0,-0.026058288,NA,10029366,Neutrophil count decreased,10022891,Investigations,Inv,venetoclax,DB11581
,2972276,DB00646,10076476,33,3420,19,1981,1,1.006046965,0.553848635,1.878024815,1,DB0064610076476_,0,0.006028756,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,nystatin,DB00646
,2972935,DB11988,10025482,111,3033,37,1189,0.456573129,1.176012723,0.798618708,1.766494551,0.623932241,DB1198810025482_,0.471713505,0.162129668,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,ocrelizumab,DB11988
,2972936,DB11988,10037660,98,3046,40,1186,0.847325893,0.953947538,0.649683862,1.423671078,0.923458044,DB1198810037660_,0.079629912,-0.0471466,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,ocrelizumab,DB11988
,2974282,DB00169,10017581,106,38585,40,18135,0.249208194,1.245469844,0.857773567,1.840491262,0.408610653,DB0016910017581_,0.894992525,0.219512843,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,2974285,DB00264,10017581,61,29546,25,24867,0.002235078,2.053528443,1.269568321,3.415254417,0.010650658,DB0026410017581_,4.542133592,0.719559505,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,2974287,DB00678,10017581,43,15556,18,10706,0.089274555,1.644056458,0.927870334,3.030322985,0.19408544,DB0067810017581_,1.639456802,0.497166638,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,losartan,DB00678
,2974288,DB00695,10017581,62,27987,39,20489,0.481789761,1.163808216,0.767006093,1.785270738,0.646303109,DB0069510017581_,0.436486676,0.151697573,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,furosemide,DB00695
,2974293,DB08932,10017581,46,19397,16,6581,0.884776833,0.975427766,0.541594174,1.847088372,0.95196507,DB0893210017581_,0.049226936,-0.02487917,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,2974930,DB00762,10076476,39,1124,31,1338,0.113487716,1.497332086,0.903803616,2.499748599,0.231361022,DB0076210076476_,1.463775921,0.403684915,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,irinotecan,DB00762
,2974951,DB11988,10003549,104,3040,56,1170,0.04883507,0.714814217,0.507835976,1.015025018,0.122805352,DB1198810003549_,2.09715468,-0.335732606,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,ocrelizumab,DB11988
,2974953,DB11988,10044565,37,3107,20,1206,0.237074198,0.718146329,0.404289915,1.311495234,0.3944234,DB1198810044565_,0.930330328,-0.331081929,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,ocrelizumab,DB11988
,2975000,DB00005,10079843,726,127356,291,42128,0.006348972,0.825247869,0.719006557,0.949195858,0.024780269,DB0000510079843_,3.697707548,-0.19207149,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,2975091,DB01076,10079843,30,25717,21,25562,0.2623244,1.419945459,0.786102198,2.610188439,0.424071888,DB0107610079843_,0.857852292,0.350618462,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,2975161,DB00563,10079843,70,46576,25,15323,0.721666333,0.921162271,0.575809623,1.51883394,0.836007033,DB0056310079843_,0.179118254,-0.082119068,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,2975490,DB00115,10017581,46,18379,28,10444,0.808980776,0.933568542,0.57088945,1.551986143,0.896971703,DB0011510017581_,0.108730963,-0.068740894,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,2975492,DB00563,10017581,56,46590,14,15334,0.407577427,1.316486733,0.723043319,2.561798959,0.577004341,DB0056310017581_,0.549905489,0.274966622,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,2975494,DB00999,10017581,54,21376,10,12229,0.000368096,3.089194331,1.556765633,6.806974606,0.00239342,DB0099910017581_,6.035031947,1.127910323,female,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,hydrochlorothiazide,DB00999
,2976861,DB00005,10017581,110,127972,32,42387,0.561151509,1.138569202,0.761860888,1.745220073,0.713639955,DB0000510017581_,0.337376709,0.129772388,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,2976863,DB00316,10017581,100,65374,59,36894,0.804402986,0.956545779,0.686349396,1.343280272,0.894310352,DB0031610017581_,0.111702414,-0.044426631,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,2976870,DB08895,10017581,65,28049,15,6631,1,1.024436826,0.577396353,1.935516484,1,DB0889510017581_,0,0.024143024,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,2978194,DB00073,10076308,300,7106,172,6235,9.64554390550589e-06,1.530345335,1.26046762,1.862688496,0.000105354,DB0007310076308_,9.158185106,0.425493419,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,rituximab,DB00073
,2978202,DB11581,10076308,185,1568,283,2477,0.763842068,1.032692793,0.844070546,1.261172007,0.869366678,DB1158110076308_,0.139990289,0.032169753,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,venetoclax,DB11581
,2978566,DB12159,10003239,146,2927,89,1979,0.495992662,1.109144866,0.84081995,1.469697476,0.658355314,DB1215910003239_,0.418010502,0.103589328,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,dupilumab,DB12159
,2978841,DB00563,10010833,58,46588,22,15326,0.603979328,0.867304309,0.522515499,1.488685496,0.747438637,DB0056310010833_,0.291103068,-0.142365373,NA,10010833,Contraindication to medical treatment,10041244,Social circumstances,SocCi,methotrexate,DB00563
,2980364,DB12159,10013968,49,3024,23,2045,0.182715986,1.440621505,0.857995425,2.485693924,0.327325929,DB1215910013968_,1.116798879,0.365074621,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dupilumab,DB12159
,2980369,DB12159,10046735,84,2989,49,2019,0.473709773,1.157893864,0.800629304,1.690331619,0.639638162,DB1215910046735_,0.446852634,0.146602721,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,dupilumab,DB12159
,2982292,DB00635,10017581,81,32972,23,23771,3.57055945729947e-05,2.538915778,1.580859089,4.230000842,0.000330686,DB0063510017581_,8.014340284,0.931737131,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,2982293,DB00641,10017581,33,14091,20,12455,0.215075971,1.458406569,0.811947073,2.683497372,0.36750425,DB0064110017581_,1.001020397,0.377344448,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,simvastatin,DB00641
,2982632,DB05679,10079843,96,6835,71,4838,0.812565848,0.957037047,0.695247409,1.322734289,0.899201908,DB0567910079843_,0.106247678,-0.043913177,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,ustekinumab,DB05679
,2983193,DB06403,10079221,67,21404,11,6650,0.045686107,1.892268491,0.992135334,3.973968833,0.116883329,DB0640310079221_,2.146579029,0.637776369,NA,10079221,Intentional dose omission,10022117,"Injury, poisoning and procedural complications",Inj&P,ambrisentan,DB06403
,2983358,DB01076,10017581,69,25678,41,25542,0.009685273,1.673986892,1.120795282,2.528513164,0.034693022,DB0107610017581_,3.36121672,0.515208142,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,2984619,DB01281,10079843,148,8784,32,1766,0.687751342,0.929836694,0.62863065,1.413649492,0.811744231,DB0128110079843_,0.208569975,-0.072746306,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,abatacept,DB01281
,2985354,DB00051,10079843,41,25690,17,11403,0.88741183,1.070505336,0.594614014,2.010727045,0.953330743,DB0005110079843_,0.047793381,0.068130814,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,2985452,DB00722,10017581,41,25362,42,25990,1,1.000376948,0.63418938,1.576893348,1,DB0072210017581_,0,0.000376877,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,2986144,DB12159,10037087,155,2918,97,1971,0.59843754,1.079347823,0.82643574,1.415195424,0.74325753,DB1215910037087_,0.296712686,0.076356991,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,dupilumab,DB12159
,2986445,DB09029,10079843,123,11221,68,7202,0.333723818,1.160992116,0.855100235,1.587509697,0.502833509,DB0902910079843_,0.68749616,0.149274912,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,2986451,DB00451,10017581,97,47174,27,15392,0.531392674,1.172190392,0.758214648,1.869139014,0.688231408,DB0045110017581_,0.373630149,0.158874128,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,2986452,DB00787,10017581,30,16970,20,17228,0.157986076,1.522777623,0.836286441,2.830281452,0.294766042,DB0078710017581_,1.221573314,0.420536051,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,acyclovir,DB00787
,2986453,DB01068,10017581,30,13733,20,6820,0.297355183,0.744902508,0.408940129,1.385104838,0.463251599,DB0106810017581_,0.769484962,-0.294501931,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,clonazepam,DB01068
,2986454,DB00451,10079843,67,47204,12,15407,0.050637349,1.822256379,0.97723975,3.702693488,0.126172577,DB0045110079843_,2.070104652,0.600075502,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,2986455,DB00635,10079843,52,33001,24,23770,0.080527865,1.560594937,0.94460273,2.648086216,0.179287367,DB0063510079843_,1.718765357,0.445067119,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,2986489,DB13874,10028813,51,426,40,638,0.00375475,1.90844655,1.21299126,3.020148895,0.016208652,DB1387410028813_,4.12221013,0.646289586,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,enasidenib,DB13874
,2986491,DB13874,10035528,25,452,32,646,0.68174413,1.116455982,0.625069642,1.97411791,0.8075468,DB1387410035528_,0.213754269,0.110159366,NA,10035528,Platelet count decreased,10022891,Investigations,Inv,enasidenib,DB13874
,2986707,DB11988,10046735,90,3054,39,1187,0.618918288,0.896962017,0.605525791,1.350073397,0.75982659,DB1198810046735_,0.274665043,-0.108741763,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,ocrelizumab,DB11988
,2990318,DB00331,10017581,42,24904,32,20720,0.727587755,1.092023508,0.67282497,1.787878912,0.840939413,DB0033110017581_,0.173235663,0.088032405,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,2990320,DB00480,10017581,90,67338,89,67573,0.940485413,1.014766574,0.748400306,1.376181338,0.979792675,DB0048010017581_,0.020414286,0.014658609,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,2991942,DB05219,10053762,46,1172,32,592,0.179889619,0.726212079,0.4472558,1.191895111,0.32371038,DB0521910053762_,1.127906052,-0.319913187,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,crisaborole,DB05219
,2995316,DB00654,10066901,767,3049,494,2104,0.29103091,1.071424757,0.942914908,1.218067091,0.456432589,DB0065410066901_,0.78431426,0.068989311,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,latanoprost,DB00654
,2995317,DB00869,10066901,237,1068,144,785,0.109992246,1.209615122,0.959051621,1.529190728,0.226047395,DB0086910066901_,1.48701059,0.190302228,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,dorzolamide,DB00869
,2996087,DB06674,10079843,37,4469,20,1470,0.088827697,0.608581916,0.342948026,1.110368622,0.193297128,DB0667410079843_,1.643526752,-0.496623756,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,golimumab,DB06674
,2999313,DB11915,10013709,196,2135,113,1262,0.853876607,1.025266654,0.800431508,1.318013629,0.928825799,DB1191510013709_,0.073834072,0.024952729,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,valbenazine,DB11915
,2999315,DB11915,10022437,58,2273,29,1346,0.501716477,1.184325854,0.741658505,1.928776583,0.663172134,DB1191510022437_,0.410720694,0.169173714,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,valbenazine,DB11915
,2999321,DB11915,10044565,133,2198,80,1295,0.884082856,0.97949407,0.730168436,1.320744159,0.951679822,DB1191510044565_,0.049526623,-0.020719096,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,valbenazine,DB11915
,2999361,DB11915,10019211,55,2276,28,1347,0.566784895,1.162505869,0.720724545,1.913348834,0.718094183,DB1191510019211_,0.331154544,0.150577907,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,valbenazine,DB11915
,2999362,DB11915,10047700,45,2286,20,1355,0.303387035,1.333561832,0.767678082,2.394762752,0.469905318,DB1191510047700_,0.755224055,0.287853432,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,valbenazine,DB11915
,3005751,DB09029,10078575,53,11291,33,7237,1,1.029409564,0.65356176,1.643091225,1,DB0902910078575_,0,0.028985399,NA,10078575,Therapeutic response shortened,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,3007641,DB06643,10079843,131,52290,9,7506,0.028854678,2.089363474,1.066904158,4.673291103,0.082164747,DB0664310079843_,2.499028935,0.736859462,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,3008329,DB11915,10016256,147,2184,86,1289,1,1.008830523,0.760726496,1.344357358,1,DB1191510016256_,0,0.008791762,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,valbenazine,DB11915
,3008340,DB11915,10034010,57,2274,35,1340,0.913040194,0.959703482,0.615501646,1.515063536,0.961085319,DB1191510034010_,0.039692092,-0.041130916,NA,10034010,Parkinsonism,10029205,Nervous system disorders,Nerv,valbenazine,DB11915
,3009056,DB01452,10013654,335,283,818,355,1.07663863158893e-10,0.51392268,0.417931308,0.631739581,3.48730085413616e-09,DB0145210013654_,19.47413779,-0.665682452,NA,10013654,Drug abuse,10037175,Psychiatric disorders,Psych,diamorphine,DB01452
,3010603,DB09303,10079843,227,26004,194,18765,0.091536381,0.844376185,0.693344774,1.029037572,0.197734531,DB0930310079843_,1.6208299,-0.169157167,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,3011630,DB12159,10012735,33,3040,20,2048,0.779165214,1.111581582,0.617233025,2.050335012,0.879672513,DB1215910012735_,0.128205585,0.10578385,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,dupilumab,DB12159
,3011631,DB12159,10028813,67,3006,21,2047,0.001385721,2.172315397,1.308813938,3.747000373,0.007202628,DB1215910028813_,4.93330934,0.775793602,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,dupilumab,DB12159
,3012545,DB06273,10076308,71,5024,49,1361,1.71116485595633e-06,0.392597725,0.267571741,0.580060711,2.31130360939425e-05,DB0627310076308_,10.67511377,-0.934969791,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tocilizumab,DB06273
,3013525,DB00181,10017581,35,9821,19,5852,0.780121206,1.09765484,0.610262449,2.033286701,0.880309353,DB0018110017581_,0.127481896,0.09317594,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,baclofen,DB00181
,3013526,DB00338,10017581,67,33607,34,22238,0.223049083,1.30394624,0.850398354,2.03296173,0.377274462,DB0033810017581_,0.97478234,0.265395235,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,3013528,DB00996,10017581,83,38870,42,22383,0.516699001,1.137993523,0.77573734,1.691716955,0.676366197,DB0099610017581_,0.391020638,0.129266644,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,3016608,DB11988,10015150,33,3111,19,1207,0.212966413,0.673922544,0.370488488,1.259623765,0.364988078,DB1198810015150_,1.007890588,-0.394640095,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,ocrelizumab,DB11988
,3016655,DB11915,10041349,233,2098,129,1246,0.567091538,1.072693068,0.851204679,1.356243188,0.718292264,DB1191510041349_,0.33087874,0.070172372,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,valbenazine,DB11915
,3016663,DB11915,10043118,145,2186,67,1308,0.092381515,1.294850443,0.954485187,1.771179594,0.199036731,DB1191510043118_,1.614265894,0.2583952,NA,10043118,Tardive dyskinesia,10029205,Nervous system disorders,Nerv,valbenazine,DB11915
,3017533,DB12159,10014184,81,2992,47,2021,0.465433144,1.164038618,0.798987042,1.71280406,0.632259758,DB1215910014184_,0.45845496,0.151895526,NA,10014184,Eczema,10040785,Skin and subcutaneous tissue disorders,Skin,dupilumab,DB12159
,3017792,DB11988,10011906,49,3095,32,1194,0.024431497,0.590809418,0.368806783,0.958272224,0.072248625,DB1198810011906_,2.627641982,-0.526261788,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,ocrelizumab,DB11988
,3020411,DB01610,10076308,55,886,65,1153,0.636319333,1.101095687,0.746239866,1.619882896,0.773934265,DB0161010076308_,0.256268337,0.096305763,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,valganciclovir,DB01610
,3025637,DB12159,10013774,82,2991,46,2022,0.361447393,1.20503398,0.825870053,1.776924037,0.531326253,DB1215910013774_,0.632379034,0.186507765,NA,10013774,Dry eye,10015919,Eye disorders,Eye,dupilumab,DB12159
,3025983,DB11988,10021789,69,3075,32,1194,0.432966396,0.837314158,0.539831076,1.323505416,0.60141213,DB1198810021789_,0.50847484,-0.177555941,NA,10021789,Infection,10021881,Infections and infestations,Infec,ocrelizumab,DB11988
,3028540,DB09302,10077040,64,2134,26,1521,0.016813134,1.754198052,1.090286522,2.897889222,0.053927177,DB0930210077040_,2.920120708,0.562011802,NA,10077040,Wrong technique in device usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,alirocumab,DB09302
,3029653,DB11569,10014011,42,3443,26,2286,0.804790579,1.072542607,0.640417572,1.827535817,0.894427482,DB1156910014011_,0.11157145,0.070032097,NA,10014011,Ear infection,10021881,Infections and infestations,Infec,ixekizumab,DB11569
,3037053,DB00316,10079843,33,65441,18,36935,1,1.034737452,0.565873131,1.952100113,1,DB0031610079843_,0,0.034147725,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,3038015,DB11988,10008479,43,3101,10,1216,0.165753467,1.686014456,0.830914732,3.774741796,0.305132184,DB1198810008479_,1.187010207,0.522367434,NA,10008479,Chest pain,10018065,General disorders and administration site conditions,Genrl,ocrelizumab,DB11988
,3038087,DB00404,10017581,41,19851,16,9846,0.482423658,1.270933157,0.697520041,2.427521489,0.646843021,DB0040410017581_,0.435651639,0.2397514,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,alprazolam,DB00404
,3038161,DB01073,10076476,88,977,93,1557,0.009156317,1.507688919,1.100898692,2.063696902,0.033178082,DB0107310076476_,3.40586581,0.410577962,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,fludarabine,DB01073
,3038165,DB06285,10079843,153,8697,8,1098,0.010749346,2.414388652,1.190356628,5.708936559,0.037715619,DB0628510079843_,3.277680974,0.881446109,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,teriparatide,DB06285
,3040248,DB12159,10040844,41,3032,43,2025,0.043347344,0.636887613,0.403277477,1.004453674,0.112365379,DB1215910040844_,2.185999408,-0.451162071,NA,10040844,Skin exfoliation,10040785,Skin and subcutaneous tissue disorders,Skin,dupilumab,DB12159
,3043551,DB00381,10017581,51,29309,31,22856,0.316302271,1.282936941,0.805038886,2.075084277,0.483975369,DB0038110017581_,0.725721264,0.249151935,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,3046706,DB08895,10079317,110,28004,57,6589,4.18499853073989e-06,0.454073018,0.326442463,0.637467329,5.04946919350461e-05,DB0889510079317_,9.893642337,-0.789497262,NA,10079317,Drug effective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,3051170,DB00060,10017581,41,9467,9,2456,0.729255718,1.181819207,0.564810582,2.769308779,0.842274653,DB0006010017581_,0.171649126,0.167054952,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,interferon beta-1a,DB00060
,3052091,DB11988,10012378,44,3100,16,1210,0.885666498,1.073369326,0.591119914,2.046017858,0.952411128,DB1198810012378_,0.04875848,0.070802604,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,ocrelizumab,DB11988
,3052133,DB11988,10037844,98,3046,51,1175,0.094864979,0.741300204,0.519461184,1.068699105,0.203012548,DB1198810037844_,1.594487491,-0.299349602,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,ocrelizumab,DB11988
,3052174,DB11988,10067482,43,3101,18,1208,0.77557592,0.930606344,0.523111475,1.721543949,0.877771785,DB1198810067482_,0.130368646,-0.071918922,NA,10067482,No adverse event,10018065,General disorders and administration site conditions,Genrl,ocrelizumab,DB11988
,3052995,DB12159,10052140,105,2968,67,2001,0.752310344,1.056565535,0.76602193,1.465664034,0.860395831,DB1215910052140_,0.150362727,0.055023586,NA,10052140,Eye pruritus,10015919,Eye disorders,Eye,dupilumab,DB12159
,3054518,DB00091,10079843,42,5468,8,2662,0.010023978,2.555627792,1.183106419,6.311382191,0.035639152,DB0009110079843_,3.334310471,0.938297905,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclosporine,DB00091
,3054520,DB00169,10079843,42,38649,17,18158,0.676496782,1.160714489,0.646553864,2.175469694,0.80384645,DB0016910079843_,0.21834701,0.149035754,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,3055011,DB11915,10037844,52,2279,22,1353,0.223968187,1.403124603,0.833019145,2.437583058,0.378488094,DB1191510037844_,0.971570663,0.338701609,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,valbenazine,DB11915
,3060434,DB00193,10017581,41,19279,15,8687,0.56440813,1.231593156,0.667018568,2.396734704,0.71622216,DB0019310017581_,0.333764881,0.20830858,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,3060437,DB01373,10017581,53,22667,14,7367,0.570669613,1.230380554,0.672502955,2.402737181,0.721156287,DB0137310017581_,0.3268994,0.207323515,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,calcium,DB01373
,3062388,DB11915,10038743,39,2292,25,1350,0.794349796,0.918870636,0.539512256,1.591778257,0.888585154,DB1191510038743_,0.118124796,-0.084609932,NA,10038743,Restlessness,10037175,Psychiatric disorders,Psych,valbenazine,DB11915
,3063913,DB01281,10076308,63,8869,14,1784,0.758945383,0.905161581,0.500286847,1.753493632,0.865568244,DB0128110076308_,0.144369058,-0.099641808,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,abatacept,DB01281
,3064448,DB06637,10017581,41,6121,10,2009,0.514472742,1.345616383,0.661349592,3.018442067,0.674418959,DB0663710017581_,0.393903761,0.296852185,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,dalfampridine,DB06637
,3064974,DB11915,10002855,68,2263,49,1326,0.285668017,0.813208969,0.551258856,1.207066086,0.450300908,DB1191510002855_,0.797839235,-0.206767168,NA,10002855,Anxiety,10037175,Psychiatric disorders,Psych,valbenazine,DB11915
,3065477,DB12159,10013573,37,3036,24,2044,1,1.037929763,0.602522384,1.819389921,1,DB1215910013573_,0,0.037228117,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,dupilumab,DB12159
,3065518,DB12159,10015150,119,2954,79,1989,0.941233621,1.01424581,0.752216635,1.373725789,0.98041672,DB1215910015150_,0.019777573,0.014145292,NA,10015150,Erythema,10040785,Skin and subcutaneous tissue disorders,Skin,dupilumab,DB12159
,3065543,DB12159,10053762,41,3032,48,2020,0.008782472,0.569150706,0.364304367,0.885527887,0.032086634,DB1215910053762_,3.439315727,-0.563610019,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,dupilumab,DB12159
,3065997,DB12159,10015946,56,3017,60,2008,0.012553102,0.621268849,0.421836196,0.913745003,0.042685417,DB1215910015946_,3.153897936,-0.475991361,NA,10015946,Eye irritation,10015919,Eye disorders,Eye,dupilumab,DB12159
,3068243,DB13879,10019211,619,1966,693,2125,0.589364146,0.965451998,0.850649728,1.095637953,0.73618004,DB1387910019211_,0.30628057,-0.035158896,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,glecaprevir,DB13879
,3068572,DB00230,10017581,124,19550,34,8617,0.01497566,1.607479715,1.091216832,2.425914804,0.049247496,DB0023010017581_,3.010896762,0.474667558,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,3068574,DB00497,10017581,32,19235,23,16352,0.589491609,1.182765252,0.670518754,2.117574348,0.736251785,DB0049710017581_,0.306183119,0.167855131,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,oxycodone,DB00497
,3071199,DB11915,10028813,87,2244,28,1347,0.004261458,1.864828172,1.19849203,2.982410593,0.017988184,DB1191510028813_,4.018040158,0.623168916,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,valbenazine,DB11915
,3073406,DB00047,10079843,79,9206,83,8435,0.386347875,0.872101248,0.631705562,1.203167654,0.556499274,DB0004710079843_,0.586089412,-0.136849752,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,3076441,DB01234,10017581,50,31575,49,32839,0.840671579,1.0612837,0.700951947,1.607560109,0.918624476,DB0123410017581_,0.084877863,0.059479213,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,dexamethasone,DB01234
,3079274,DB11988,10017577,74,3070,30,1196,0.826095027,0.960962458,0.617217896,1.530108302,0.908208703,DB1198810017577_,0.096281078,-0.039819936,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,ocrelizumab,DB11988
,3086589,DB11915,10016322,52,2279,26,1349,0.55416863,1.183840004,0.721936223,1.985004943,0.707721428,DB1191510016322_,0.345704726,0.168763395,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,valbenazine,DB11915
,3090707,DB05316,10017581,30,4326,83,6912,0.008663374,0.577537749,0.366459623,0.888214995,0.031748595,DB0531610017581_,3.449906802,-0.548981473,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,3091500,DB08934,10079221,21,4468,32,6172,0.781399141,0.906516008,0.496100521,1.623814471,0.880938299,DB0893410079221_,0.126767691,-0.09814659,NA,10079221,Intentional dose omission,10022117,"Injury, poisoning and procedural complications",Inj&P,sofosbuvir,DB08934
,3092148,DB06605,10079843,41,14032,16,13017,0.003150237,2.376942524,1.304568952,4.539926921,0.014079915,DB0660510079843_,4.263005968,0.865815008,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,3094137,DB11915,10013916,67,2264,29,1346,0.165402551,1.373440345,0.870948611,2.214812818,0.304656884,DB1191510013916_,1.188569107,0.317318793,NA,10013916,Dyskinesia,10029205,Nervous system disorders,Nerv,valbenazine,DB11915
,3099350,DB12159,10047571,40,3033,16,2052,0.076290685,1.691229606,0.923264184,3.244136746,0.171951694,DB1215910047571_,1.760541691,0.525455842,NA,10047571,Visual impairment,10015919,Eye disorders,Eye,dupilumab,DB12159
,3099401,DB09303,10017581,51,26180,28,18931,0.255685146,1.317083105,0.814655312,2.170110432,0.416412161,DB0930310017581_,0.876079738,0.275419523,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,evolocumab,DB09303
,3103423,DB00190,10017581,32,3265,46,4628,1,0.98605881,0.606276958,1.586088069,1,DB0019010017581_,0,-0.014039281,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,carbidopa,DB00190
,3105220,DB13874,10016256,29,448,57,621,0.171616978,0.705447427,0.427539492,1.142583382,0.312923747,DB1387410016256_,1.161795739,-0.348923029,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,enasidenib,DB13874
,3107099,DB11988,10020772,41,3103,14,1212,0.763436244,1.143831781,0.60820168,2.280452698,0.869036494,DB1198810020772_,0.140370159,0.134383838,NA,10020772,Hypertension,10047065,Vascular disorders,Vasc,ocrelizumab,DB11988
,3110212,DB11988,10040753,39,3105,12,1214,0.533310358,1.270606291,0.64909763,2.675001904,0.690069054,DB1198810040753_,0.370963608,0.239494181,NA,10040753,Sinusitis,10021881,Infections and infestations,Infec,ocrelizumab,DB11988
,3117147,DB00005,10079221,66,128016,27,42392,0.339529145,0.809457282,0.51003599,1.318040299,0.508621296,DB0000510079221_,0.676051555,-0.211391278,NA,10079221,Intentional dose omission,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,3122431,DB06605,10074414,35,14038,20,13013,0.104218334,1.622186687,0.910373687,2.967280244,0.217367896,DB0660510074414_,1.526163986,0.483775046,NA,10074414,Catheter management,10042613,Surgical and medical procedures,Surg,apixaban,DB06605
,3122635,DB13874,10011906,86,391,147,531,0.136667444,0.79466689,0.58299678,1.078746649,0.265055985,DB1387410011906_,1.32781421,-0.229832259,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,enasidenib,DB13874
,3125015,DB11988,10033425,50,3094,17,1209,0.682841297,1.149243168,0.648532306,2.134419161,0.808235398,DB1198810033425_,0.212901928,0.139103611,NA,10033425,Pain in extremity,10028395,Musculoskeletal and connective tissue disorders,Musc,ocrelizumab,DB11988
,3125017,DB11988,10049848,31,3113,20,1206,0.084366474,0.600558954,0.330094399,1.116370999,0.185671937,DB1198810049848_,1.683773942,-0.509894468,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,ocrelizumab,DB11988
,3125426,DB11988,10016256,199,2945,74,1152,0.780837715,1.051921678,0.794200182,1.405320357,0.880700697,DB1198810016256_,0.127037442,0.050618661,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,ocrelizumab,DB11988
,3132501,DB11915,10012378,58,2273,29,1346,0.501716477,1.184325854,0.741658505,1.928776583,0.663172134,DB1191510012378_,0.410720694,0.169173714,NA,10012378,Depression,10037175,Psychiatric disorders,Psych,valbenazine,DB11915
,3133020,DB01452,10007515,69,549,96,1077,0.039524829,1.409781815,1.001626877,1.976117817,0.104702457,DB0145210007515_,2.256632697,0.343434951,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,diamorphine,DB01452
,3133024,DB01452,10038669,68,550,97,1076,0.059121805,1.371165183,0.973482748,1.923178086,0.14184808,DB0145210038669_,1.952998653,0.315660877,NA,10038669,Respiratory arrest,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,diamorphine,DB01452
,3133632,DB12159,10010264,101,2972,60,2008,0.463076083,1.137337211,0.813823573,1.600980594,0.630214085,DB1215910010264_,0.461695699,0.128689751,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,3138826,DB11834,10003239,35,907,34,754,0.539568241,0.855841653,0.512874724,1.429532563,0.695342398,DB1183410003239_,0.363350896,-0.155669905,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,guselkumab,DB11834
,3139799,DB08881,10076308,26,597,31,780,0.785665614,1.095730505,0.61763997,1.929894074,0.883734037,DB0888110076308_,0.123599125,0.091421268,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,vemurafenib,DB08881
,3140176,DB00213,10017581,50,18845,22,13399,0.071815694,1.615907773,0.960166375,2.803629178,0.164452448,DB0021310017581_,1.80513382,0.479896887,NA,10017581,Gait inability,10018065,General disorders and administration site conditions,Genrl,pantoprazole,DB00213
,3140860,DB12159,10020751,45,3028,18,2050,0.069638051,1.692370848,0.957103194,3.115791304,0.16064913,DB1215910020751_,1.828532611,0.526130415,NA,10020751,Hypersensitivity,10021428,Immune system disorders,Immun,dupilumab,DB12159
,3145161,DB01221,10012218,34,497,17,579,0.005878812,2.328281118,1.247408335,4.50149943,0.023294576,DB0122110012218_,3.759534715,0.845130278,NA,10012218,Delirium,10037175,Psychiatric disorders,Psych,ketamine,DB01221
,3148362,DB12159,10067152,36,3037,14,2054,0.08285493,1.738944029,0.912544109,3.499417803,0.183158137,DB1215910067152_,1.697405364,0.553278049,NA,10067152,Oral herpes,10021881,Infections and infestations,Infec,dupilumab,DB12159
,3155332,DB09331,10028810,37,2048,16,2413,0.000722714,2.72406411,1.473383818,5.260309987,0.004205099,DB0933110028810_,5.471457375,1.002124923,female,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,daratumumab,DB09331
,3159430,DB11988,10022000,50,3094,21,1205,0.790306347,0.927313037,0.544147449,1.63278187,0.886410114,DB1198810022000_,0.120575553,-0.075464082,NA,10022000,Influenza,10021881,Infections and infestations,Infec,ocrelizumab,DB11988
,3162002,DB12159,10076309,113,2960,77,1991,0.940010118,0.987113286,0.728035385,1.344158824,0.979394559,DB1215910076309_,0.020820695,-0.012970468,NA,10076309,Product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,dupilumab,DB12159
,3162080,DB12159,10037660,45,3028,22,2046,0.258999731,1.382015696,0.809877563,2.424505233,0.420084558,DB1215910037660_,0.867299259,0.323543083,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,3162086,DB12159,10022095,78,2995,26,2042,0.001172022,2.045139404,1.292008371,3.334260817,0.006279544,DB1215910022095_,5.070457945,0.715465955,NA,10022095,Injection site reaction,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,3163445,DB11834,10012735,30,912,24,764,0.89058085,1.047131734,0.586250278,1.888930108,0.954671384,DB1183410012735_,0.046388098,0.046054745,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,guselkumab,DB11834
,3163446,DB11834,10019211,45,897,29,759,0.284303682,1.312791555,0.79644532,2.194322126,0.44878373,DB1183410019211_,0.801214177,0.272155828,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,guselkumab,DB11834
,3164671,DB00043,10076308,62,6351,42,2258,0.001666009,0.524911009,0.348003076,0.798566788,0.008373048,DB0004310076308_,4.782737292,-0.644526538,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,omalizumab,DB00043
,3167839,DB11988,10003239,47,3097,17,1209,0.888845504,1.079260422,0.605497051,2.013283564,0.953896257,DB1198810003239_,0.047200359,0.076276012,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,ocrelizumab,DB11988
,3173235,DB12159,10033371,68,3005,27,2041,0.019793976,1.710410084,1.07608401,2.789592784,0.061303719,DB1215910033371_,2.791914766,0.536733157,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,3177705,DB01452,10013663,15,603,36,1137,0.550224169,0.785737706,0.396370424,1.48545239,0.70456678,DB0145210013663_,0.350172162,-0.24113225,NA,10013663,Drug dependence,10037175,Psychiatric disorders,Psych,diamorphine,DB01452
,3180043,DB00465,10066901,91,2013,55,828,0.032207638,0.680651743,0.476700169,0.979235534,0.089542311,DB0046510066901_,2.413044021,-0.384704495,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,ketorolac,DB00465
,3197336,DB11915,10049848,62,2269,31,1344,0.514480188,1.184651187,0.753461198,1.897100547,0.674418959,DB1191510049848_,0.393903761,0.169448374,NA,10049848,Balance disorder,10029205,Nervous system disorders,Nerv,valbenazine,DB11915
,3206093,DB01097,10078504,68,6197,9,1494,0.109215266,1.821384217,0.902449862,4.162636041,0.22485973,DB0109710078504_,1.492278493,0.599596771,NA,10078504,Contraindicated product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,leflunomide,DB01097
,3214007,DB13879,10016256,679,1906,842,1976,0.00331149,0.836059821,0.74077074,0.943415145,0.014654855,DB1387910016256_,4.222983574,-0.179055112,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,glecaprevir,DB13879
,3244592,DB11988,10048393,123,3021,57,1169,0.271481765,0.835073148,0.600460176,1.172917307,0.434281605,DB1198810048393_,0.834062096,-0.180235955,NA,10048393,Multiple sclerosis relapse,10029205,Nervous system disorders,Nerv,ocrelizumab,DB11988
,3246214,DB05316,10033295,37,4319,57,6938,0.832240007,1.042711457,0.668916258,1.607947725,0.912520147,DB0531610033295_,0.091545115,0.04182449,NA,10033295,Overdose,10022117,"Injury, poisoning and procedural complications",Inj&P,pimavanserin,DB05316
,3255124,DB08895,10079221,45,28069,11,6635,0.865900838,0.967014051,0.492105503,2.074380479,0.939184762,DB0889510079221_,0.062743055,-0.033542254,NA,10079221,Intentional dose omission,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,3255664,DB11915,10039897,84,2247,53,1322,0.71881315,0.932481916,0.648708008,1.350472446,0.833914209,DB1191510039897_,0.181624748,-0.069905521,NA,10039897,Sedation,10029205,Nervous system disorders,Nerv,valbenazine,DB11915
,3255699,DB11915,10046735,60,2271,22,1353,0.063677314,1.624635916,0.976840893,2.79486409,0.15009265,DB1191510046735_,1.896502508,0.485283739,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,valbenazine,DB11915
,3258345,DB13874,10000880,18,459,41,637,0.102850574,0.609527108,0.325181775,1.101280314,0.215266739,DB1387410000880_,1.535877375,-0.495071856,NA,10000880,Acute myeloid leukaemia,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,enasidenib,DB13874
,3279702,DB11988,10013709,58,3086,33,1193,0.09788826,0.679516445,0.433275618,1.081606098,0.207710619,DB1198810013709_,1.571609421,-0.386373843,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,ocrelizumab,DB11988
,3279704,DB11988,10028334,57,3087,15,1211,0.18738075,1.490633525,0.828799026,2.846168692,0.33324107,DB1198810028334_,1.098889117,0.399201214,NA,10028334,Muscle spasms,10028395,Musculoskeletal and connective tissue disorders,Musc,ocrelizumab,DB11988
,3286157,DB11988,10033371,105,3039,23,1203,0.009238972,1.806945715,1.135787337,2.98946257,0.033413096,DB1198810033371_,3.398807353,0.59163797,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,ocrelizumab,DB11988
,3286546,DB12159,10012438,92,2981,61,2007,1,1.015412217,0.722907568,1.434790958,1,DB1215910012438_,0,0.015294656,NA,10012438,Dermatitis atopic,10040785,Skin and subcutaneous tissue disorders,Skin,dupilumab,DB12159
,3303879,DB11988,10047899,116,3028,22,1204,0.000988234,2.09625501,1.313208546,3.491118953,0.00545079,DB1198810047899_,5.211994636,0.740152424,NA,10047899,Weight increased,10022891,Investigations,Inv,ocrelizumab,DB11988
,3305158,DB11988,10016322,50,3094,11,1215,0.085621796,1.784778648,0.913270739,3.81521716,0.187743368,DB1198810016322_,1.672679311,0.579294401,NA,10016322,Feeling abnormal,10018065,General disorders and administration site conditions,Genrl,ocrelizumab,DB11988
,3309245,DB13879,10037087,250,2335,121,2697,4.42617991489832e-15,2.38606522,1.898817897,3.011140896,2.73103612824184e-13,DB1387910037087_,28.92892514,0.869645658,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,glecaprevir,DB13879
,3312040,DB01452,10011906,52,566,57,1116,0.003504696,1.79822293,1.193429704,2.704414742,0.015335597,DB0145210011906_,4.177578539,0.586798916,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,diamorphine,DB01452
,3312111,DB11988,10028245,66,3078,38,1188,0.059904023,0.670426364,0.440413275,1.033314101,0.143297999,DB1198810028245_,1.942828906,-0.399841405,NA,10028245,Multiple sclerosis,10029205,Nervous system disorders,Nerv,ocrelizumab,DB11988
,3313513,DB12159,10076476,33,3040,26,2042,0.593861934,0.852586399,0.492864116,1.489237755,0.739917093,DB1215910076476_,0.301217136,-0.159480727,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,dupilumab,DB12159
,3314631,DB11915,10011906,100,2231,82,1293,0.027330439,0.706873875,0.518141174,0.966478135,0.078713701,DB1191510011906_,2.541938051,-0.346903024,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,valbenazine,DB11915
,3315046,DB13879,10003549,22,2563,30,2788,0.486254469,0.79774533,0.437243608,1.434203647,0.650136259,DB1387910003549_,0.430573308,-0.225965867,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,glecaprevir,DB13879
,3316639,DB13879,10012735,120,2465,142,2676,0.526283635,0.917444605,0.708873251,1.185764211,0.684176534,DB1387910012735_,0.379539304,-0.086163077,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,glecaprevir,DB13879
,3317105,DB11915,10013968,45,2286,20,1355,0.303387035,1.333561832,0.767678082,2.394762752,0.469905318,DB1191510013968_,0.755224055,0.287853432,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,valbenazine,DB11915
,3317226,DB12159,10013786,55,3018,17,2051,0.003503711,2.198356151,1.252644637,4.052646063,0.015334552,DB1215910013786_,4.177646678,0.787709877,NA,10013786,Dry skin,10040785,Skin and subcutaneous tissue disorders,Skin,dupilumab,DB12159
,3317228,DB05679,10078156,34,6897,23,4886,0.893721596,1.047237454,0.598290967,1.864558457,0.955748455,DB0567910078156_,0.045260523,0.0461557,NA,10078156,Insurance issue,10041244,Social circumstances,SocCi,ustekinumab,DB05679
,3327501,DB00016,10079843,49,2713,58,2232,0.076816867,0.695102286,0.463270337,1.039247064,0.172885637,DB0001610079843_,1.755124959,-0.36369627,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,erythropoietin,DB00016
,3328430,DB08907,10060803,18,4235,66,3844,8.5103355193825e-09,0.247559151,0.138064744,0.422941863,1.94347670831424e-07,DB0890710060803_,15.45361716,-1.396105731,male,10060803,Diabetic foot infection,10021881,Infections and infestations,Infec,canagliflozin,DB08907
,3333942,DB12159,10042682,35,3038,16,2052,0.250640224,1.477426479,0.794004643,2.866748209,0.410459381,DB1215910042682_,0.890478306,0.390301709,NA,10042682,Swelling face,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,3336453,DB11915,10061623,49,2282,31,1344,0.815144001,0.930951068,0.578635877,1.518308651,0.900803434,DB1191510061623_,0.10446821,-0.071548561,NA,10061623,Adverse drug reaction,10018065,General disorders and administration site conditions,Genrl,valbenazine,DB11915
,3336537,DB11915,10016173,100,2231,68,1307,0.369008649,0.861563863,0.621768162,1.199700208,0.538612239,DB1191510016173_,0.618759375,-0.149006096,NA,10016173,Fall,10022117,"Injury, poisoning and procedural complications",Inj&P,valbenazine,DB11915
,3338042,DB13879,10033371,51,2534,38,2780,0.086436592,1.472279879,0.944903934,2.311632975,0.189087913,DB1387910033371_,1.665543223,0.386812137,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,glecaprevir,DB13879
,3338689,DB11988,10012735,50,3094,16,1210,0.5811796,1.222057016,0.681255684,2.308285551,0.729571902,DB1198810012735_,0.315297352,0.200535517,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,ocrelizumab,DB11988
,3338733,DB11988,10076308,91,3053,36,1190,0.920456901,0.985281655,0.658711001,1.501475555,0.964796811,DB1198810076308_,0.035837758,-0.014827734,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ocrelizumab,DB11988
,3340320,DB11915,10053762,72,2259,48,1327,0.502806722,0.881176134,0.599080785,1.306027262,0.66396758,DB1191510053762_,0.409521956,-0.126497748,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,valbenazine,DB11915
,3342257,DB11988,10020937,56,3088,19,1207,0.697596809,1.151990569,0.670784859,2.061984185,0.81818943,DB1198810020937_,0.200661392,0.141491375,NA,10020937,Hypoaesthesia,10029205,Nervous system disorders,Nerv,ocrelizumab,DB11988
,3342971,DB05351,10048302,37,2686,15,1116,1,1.024879203,0.546448997,2.01863096,1,DB0535110048302_,0,0.024574755,NA,10048302,Tubulointerstitial nephritis,10038359,Renal and urinary disorders,Renal,dexlansoprazole,DB05351
,3343486,DB11915,10003549,44,2287,34,1341,0.23769975,0.758891253,0.471460806,1.230954532,0.395151498,DB1191510003549_,0.928486047,-0.275896789,NA,10003549,Asthenia,10018065,General disorders and administration site conditions,Genrl,valbenazine,DB11915
,3343489,DB11915,10013573,105,2226,67,1308,0.628010384,0.920889229,0.66598289,1.280606553,0.767336353,DB1191510013573_,0.264830043,-0.082415522,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,valbenazine,DB11915
,3343811,DB12159,10025482,38,3035,17,2051,0.168926311,1.510456133,0.829528134,2.862101543,0.30939844,DB1215910025482_,1.173125384,0.41241168,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,3344819,DB01073,10012818,20,1045,41,1609,0.353576011,0.751156338,0.414459037,1.320383347,0.523384888,DB0107310012818_,0.647438162,-0.286141476,NA,10012818,Diffuse large B-cell lymphoma,10029104,"Neoplasms benign, malignant and unspecified (incl cysts and polyps)",Neopl,fludarabine,DB01073
,3348679,DB12023,10019211,113,1000,34,473,0.025214189,1.571622228,1.044373391,2.416977233,0.073972316,DB1202310019211_,2.60406437,0.452108352,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,benralizumab,DB12023
,3376728,DB11988,10003988,42,3102,10,1216,0.165726756,1.646288807,0.809609477,3.691617854,0.305113985,DB1198810003988_,1.18706985,0.498523547,NA,10003988,Back pain,10028395,Musculoskeletal and connective tissue disorders,Musc,ocrelizumab,DB11988
,3377064,DB13879,10013573,59,2526,55,2763,0.448589568,1.173338483,0.795320412,1.733413716,0.616258228,DB1387910013573_,0.484089203,0.15985309,NA,10013573,Dizziness,10029205,Nervous system disorders,Nerv,glecaprevir,DB13879
,3381548,DB12159,10003553,32,3041,21,2047,1,1.025724383,0.571695054,1.877332017,1,DB1215910003553_,0,0.025399078,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,dupilumab,DB12159
,3384117,DB13874,10012735,33,444,34,644,0.201041718,1.407337275,0.83116991,2.380677705,0.350237378,DB1387410012735_,1.049144131,0.341699462,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,enasidenib,DB13874
,3384120,DB13874,10061428,29,448,35,643,0.515856394,1.189035329,0.690159403,2.034978686,0.675582837,DB1387410061428_,0.392179499,0.173142331,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,enasidenib,DB13874
,3386942,DB11915,10013642,73,2258,77,1298,0.000370097,0.545058586,0.387267381,0.766616927,0.002403106,DB1191510013642_,6.030993242,-0.606861993,NA,10013642,Drooling,10029205,Nervous system disorders,Nerv,valbenazine,DB11915
,3390158,DB11988,10028810,74,3070,18,1208,0.07791159,1.617528056,0.95150656,2.890430997,0.174832982,DB1198810028810_,1.743924149,0.480899093,NA,10028810,Nasopharyngitis,10021881,Infections and infestations,Infec,ocrelizumab,DB11988
,3395426,DB11915,10054112,70,2261,44,1331,0.767930231,0.936549852,0.629144946,1.407197575,0.872651885,DB1191510054112_,0.13621856,-0.065552526,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,valbenazine,DB11915
,3396184,DB13879,10001760,40,2545,13,2805,4.59012168813927e-05,3.390588634,1.771522317,6.924566545,0.000410511,DB1387910001760_,7.798107971,1.221003545,female,10001760,Alopecia,10040785,Skin and subcutaneous tissue disorders,Skin,glecaprevir,DB13879
,3400611,DB00065,10078504,58,9406,11,4946,0.000850333,2.772417331,1.43913975,5.863732164,0.00481547,DB0006510078504_,5.335921595,1.019719622,female,10078504,Contraindicated product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,infliximab,DB00065
,3400612,DB00073,10078504,43,7363,7,6400,2.33652572449258e-06,5.338864546,2.3789748,14.07974003,3.03286808238457e-05,DB0007310078504_,10.40341673,1.675012999,female,10078504,Contraindicated product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,rituximab,DB00073
,3400614,DB01281,10078504,239,8693,42,1756,0.466207935,1.149470619,0.821622135,1.642787791,0.633034175,DB0128110078504_,0.457230869,0.139301505,NA,10078504,Contraindicated product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,abatacept,DB01281
,3401467,DB11834,10013709,96,846,84,704,0.752520609,0.951029467,0.689827051,1.313125592,0.860580139,DB1183410013709_,0.150148537,-0.050210232,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,guselkumab,DB11834
,3403659,DB13879,10037844,90,2495,62,2756,0.004991509,1.603309838,1.141830541,2.263608132,0.020442789,DB1387910037844_,3.890125058,0.472070141,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,glecaprevir,DB13879
,3404368,DB13879,10022437,48,2537,54,2764,0.920438732,0.968422659,0.639955253,1.461688736,0.964796811,DB1387910022437_,0.035837758,-0.032086656,NA,10022437,Insomnia,10037175,Psychiatric disorders,Psych,glecaprevir,DB13879
,3425264,DB13879,10010774,41,2544,49,2769,0.67211149,0.91077454,0.584308946,1.41315689,0.800970013,DB1387910010774_,0.22193177,-0.093459899,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,glecaprevir,DB13879
,3436821,DB00331,10080061,32,24914,38,20714,0.149796865,0.700155569,0.423295237,1.151371102,0.283656321,DB0033110080061_,1.25999191,-0.356452728,NA,10080061,Euglycaemic diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,metformin,DB00331
,3436822,DB09038,10080061,43,2205,56,2485,0.541761538,0.865389249,0.565228816,1.316910483,0.697126452,DB0903810080061_,0.360788461,-0.144575874,NA,10080061,Euglycaemic diabetic ketoacidosis,10027433,Metabolism and nutrition disorders,Metab,empagliflozin,DB09038
,3437621,DB05676,10077801,36,47093,19,25310,1,1.018321133,0.568723431,1.879824584,1,DB0567610077801_,0,0.018155323,NA,10077801,Product supply issue,10077536,Product issues,Prod,apremilast,DB05676
,3439480,DB13879,10013709,44,2541,40,2778,0.441519431,1.202553745,0.762933545,1.900541483,0.609764258,DB1387910013709_,0.494682859,0.184447416,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,glecaprevir,DB13879
,3439481,DB13879,10065154,37,2548,41,2777,1,0.983546545,0.61109396,1.578195961,1,DB1387910065154_,0,-0.016590316,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,glecaprevir,DB13879
,3442808,DB13879,10061428,32,2553,31,2787,0.70399378,1.126845826,0.663729112,1.915363928,0.82254913,DB1387910061428_,0.195347066,0.119422425,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,glecaprevir,DB13879
,3470196,DB13879,10000087,33,2552,42,2776,0.561086581,0.854705133,0.523101307,1.386029226,0.713574646,DB1387910000087_,0.337468228,-0.156998743,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,glecaprevir,DB13879
,3472711,DB13879,10047700,73,2512,71,2747,0.499811622,1.124329946,0.79595255,1.588838925,0.661524635,DB1387910047700_,0.413208054,0.117187254,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,glecaprevir,DB13879
,3484336,DB00275,10079622,34,2026,31,1206,0.093290571,0.652981244,0.387197715,1.104768885,0.200592471,DB0027510079622_,1.606479935,-0.426206873,NA,10079622,Sprue-like enteropathy,10017947,Gastrointestinal disorders,Gastr,olmesartan,DB00275
,3489763,DB13879,10000059,35,2550,56,2762,0.07281714,0.677011324,0.429112349,1.055128907,0.166232284,DB1387910000059_,1.794369165,-0.390067279,NA,10000059,Abdominal discomfort,10017947,Gastrointestinal disorders,Gastr,glecaprevir,DB13879
,3491366,DB01101,10067973,44,7545,21,3887,0.895627469,1.079406517,0.627221083,1.914021216,0.95615204,DB0110110067973_,0.044838341,0.076411369,NA,10067973,Hospice care,10042613,Surgical and medical procedures,Surg,capecitabine,DB01101
,3494701,DB13879,10013968,27,2558,32,2786,0.794131457,0.918996828,0.528070813,1.588232423,0.888490236,DB1387910013968_,0.118231621,-0.084472608,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,glecaprevir,DB13879
,3510190,DB11834,10037153,89,853,66,722,0.448133516,1.141303151,0.80752435,1.619382361,0.615867581,DB1183410037153_,0.484723305,0.132170724,NA,10037153,Psoriasis,10040785,Skin and subcutaneous tissue disorders,Skin,guselkumab,DB11834
,3518159,DB11915,10017577,57,2274,28,1347,0.495743683,1.205751859,0.75010338,1.979295375,0.658095639,DB1191510017577_,0.41840501,0.187103322,NA,10017577,Gait disturbance,10018065,General disorders and administration site conditions,Genrl,valbenazine,DB11915
,3531080,DB06273,10078504,69,5026,10,1400,0.053891587,1.921788062,0.981333682,4.195983016,0.132300399,DB0627310078504_,2.022680192,0.653256035,NA,10078504,Contraindicated product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,tocilizumab,DB06273
,3538128,DB13879,10000081,26,2559,37,2781,0.312352533,0.763703362,0.44268653,1.299765371,0.479903339,DB1387910000081_,0.734170572,-0.269575835,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,glecaprevir,DB13879
,3555534,DB05351,10077512,88,2635,78,1053,1.20689027607516e-06,0.450952541,0.325760877,0.625167873,1.69235054183171e-05,DB0535110077512_,10.98680705,-0.796393175,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,dexlansoprazole,DB05351
,3568729,DB12159,10028411,37,3036,17,2051,0.210663901,1.470230091,0.804851986,2.792381454,0.361997885,DB1215910028411_,1.016116911,0.385418913,NA,10028411,Myalgia,10028395,Musculoskeletal and connective tissue disorders,Musc,dupilumab,DB12159
,3573882,DB15566,10066901,179,828,115,547,0.844111079,1.028268243,0.788747171,1.344107712,0.921176605,DB1556610066901_,0.082103508,0.02787607,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,prednisolone acetate,DB15566
,3578388,DB00879,10079843,22,1755,94,3618,0.001740538,0.482543119,0.287677607,0.77718719,0.008667243,DB0087910079843_,4.748204548,-0.728684996,NA,10079843,Product storage error,10022117,"Injury, poisoning and procedural complications",Inj&P,emtricitabine,DB00879
,3593208,DB09303,10077040,116,26115,66,18893,0.132165588,1.271517813,0.931360356,1.748433721,0.258903896,DB0930310077040_,1.351298343,0.240211315,NA,10077040,Wrong technique in device usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,3596970,DB09303,10073311,133,26098,18,18941,8.4185264341345e-16,5.362426448,3.263693943,9.329286081,5.6738709569545e-14,DB0930310073311_,30.50031971,1.679416568,female,10073311,Occupational exposure to product,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,3599567,DB11834,10053762,42,900,39,749,0.648963508,0.896297103,0.559179866,1.439585719,0.783879685,DB1183410053762_,0.243499734,-0.109483333,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,guselkumab,DB11834
,3600065,DB09303,10080753,32,26199,44,18915,0.00704443,0.525091127,0.322142103,0.847320012,0.026924943,DB0930310080753_,3.614702161,-0.644183456,NA,10080753,Product administered at inappropriate site,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,3603734,DB12023,10008469,40,1073,15,492,0.557423583,1.222567685,0.653379643,2.406218807,0.710528651,DB1202310008469_,0.341746007,0.200953307,NA,10008469,Chest discomfort,10018065,General disorders and administration site conditions,Genrl,benralizumab,DB12023
,3604561,DB12159,10043414,39,3034,27,2041,0.900226011,0.971682256,0.57778662,1.656251278,0.956657329,DB1215910043414_,0.04431002,-0.028726425,NA,10043414,Therapeutic response decreased,10018065,General disorders and administration site conditions,Genrl,dupilumab,DB12159
,3608044,DB12023,10003553,165,948,91,416,0.122823585,0.795798129,0.596208571,1.066668724,0.245451072,DB1202310003553_,1.404657653,-0.228409732,NA,10003553,Asthma,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,benralizumab,DB12023
,3608228,DB11915,10024264,35,2296,26,1349,0.422755854,0.79098846,0.460426667,1.37478732,0.591672963,DB1191510024264_,0.524801223,-0.2344719,NA,10024264,Lethargy,10029205,Nervous system disorders,Nerv,valbenazine,DB11915
,3608980,DB08910,10061520,31,16713,19,17469,0.066945011,1.705343235,0.933000166,3.19641146,0.155838428,DB0891010061520_,1.858935529,0.533766402,NA,10061520,Ill-defined disorder,10018065,General disorders and administration site conditions,Genrl,pomalidomide,DB08910
,3614427,DB00531,10072931,52,7200,8,6508,3.2119530895338e-08,5.874619449,2.768599083,14.32760736,6.45213503694275e-07,DB0053110072931_,14.25368456,1.770641283,female,10072931,Unintentional medical device removal,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclophosphamide,DB00531
,3620951,DB12023,10025482,39,1074,15,492,0.655442365,1.190919542,0.634742879,2.348648734,0.789058467,DB1202310025482_,0.236914858,0.174725733,NA,10025482,Malaise,10018065,General disorders and administration site conditions,Genrl,benralizumab,DB12023
,3620953,DB12023,10037660,55,1058,28,479,0.628027657,0.889384125,0.546634553,1.475639622,0.767336353,DB1202310037660_,0.264830043,-0.11722605,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,benralizumab,DB12023
,3622158,DB00704,10080753,56,4300,69,5125,0.928029496,0.967305411,0.66587291,1.399865316,0.969949314,DB0070410080753_,0.030511463,-0.033241,NA,10080753,Product administered at inappropriate site,10022117,"Injury, poisoning and procedural complications",Inj&P,naltrexone,DB00704
,3623919,DB00983,10078668,194,3307,106,1634,0.41265408,0.904323236,0.704519115,1.165813296,0.582098236,DB0098310078668_,0.541116056,-0.10056842,NA,10078668,Poor quality device used,10022117,"Injury, poisoning and procedural complications",Inj&P,formoterol,DB00983
,3643252,DB13915,10014625,54,413,66,628,0.279917855,1.243861252,0.833011257,1.851211896,0.443766032,DB1391510014625_,0.81245781,0.218220454,NA,10014625,Encephalopathy,10029205,Nervous system disorders,Nerv,axicabtagene ciloleucel,DB13915
,3643256,DB13915,10021097,49,418,77,617,0.773583007,0.939359562,0.628745081,1.393043912,0.876342038,DB1391510021097_,0.13199881,-0.062556953,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,axicabtagene ciloleucel,DB13915
,3643271,DB13915,10044565,23,444,38,656,0.788726598,0.894321409,0.50126285,1.56442117,0.885552887,DB1391510044565_,0.121543098,-0.11169005,NA,10044565,Tremor,10029205,Nervous system disorders,Nerv,axicabtagene ciloleucel,DB13915
,3643326,DB13915,10052015,271,196,393,301,0.672073437,1.058892995,0.829526229,1.352557313,0.800970013,DB1391510052015_,0.22193177,0.057224018,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,axicabtagene ciloleucel,DB13915
,3649049,DB05084,10053762,104,3170,55,22,2.95952118494366e-59,0.013220185,0.007364854,0.022959115,2.43096919832013e-56,DB0508410053762_,128.0564752,-4.326010434,male,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,abaloparatide,DB05084
,3654079,DB13915,10037660,91,376,168,526,0.061744111,0.757937527,0.561454571,1.018922675,0.146647694,DB1391510037660_,1.919722205,-0.277154315,NA,10037660,Pyrexia,10018065,General disorders and administration site conditions,Genrl,axicabtagene ciloleucel,DB13915
,3654088,DB14512,10078668,347,4497,201,2211,0.08094849,0.848817769,0.705934342,1.022625843,0.179965412,DB1451210078668_,1.7149906,-0.163910758,NA,10078668,Poor quality device used,10022117,"Injury, poisoning and procedural complications",Inj&P,mometasone furoate,DB14512
,3654217,DB12023,10013968,92,1021,44,463,0.772696781,0.948211229,0.643318423,1.414867781,0.875615308,DB1202310013968_,0.13282843,-0.053177987,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,benralizumab,DB12023
,3654219,DB12023,10037087,49,1064,9,498,0.008788899,2.5470375,1.225585911,5.945836545,0.032101778,DB1202310037087_,3.438843862,0.934930919,NA,10037087,Pruritus,10040785,Skin and subcutaneous tissue disorders,Skin,benralizumab,DB12023
,3655504,DB13879,10003239,25,2560,38,2780,0.206254831,0.71447854,0.412105035,1.218675193,0.356788959,DB1387910003239_,1.030610823,-0.336202317,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,glecaprevir,DB13879
,3666311,DB13915,10002948,29,438,52,642,0.414001071,0.817579075,0.492063554,1.335719619,0.583267307,DB1391510002948_,0.539109696,-0.201407654,NA,10002948,Aphasia,10029205,Nervous system disorders,Nerv,axicabtagene ciloleucel,DB13915
,3666352,DB01225,10052015,19,5025,41,4599,0.001688046,0.424162568,0.232166734,0.748847667,0.008461661,DB0122510052015_,4.772209786,-0.857638483,NA,10052015,Cytokine release syndrome,10021428,Immune system disorders,Immun,enoxaparin,DB01225
,3668909,DB13879,10011906,25,2560,45,2773,0.053256073,0.60183715,0.35257431,1.006010967,0.131107603,DB1387910011906_,2.031736892,-0.507768385,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,glecaprevir,DB13879
,3688596,DB13915,10029350,170,297,278,416,0.219192113,0.856642414,0.667129421,1.098752231,0.372517063,DB1391510029350_,0.987472436,-0.154734701,NA,10029350,Neurotoxicity,10029205,Nervous system disorders,Nerv,axicabtagene ciloleucel,DB13915
,3692729,DB13915,10010305,38,429,60,634,0.82973981,0.936015805,0.595000661,1.457534973,0.91066932,DB1391510010305_,0.093575433,-0.066122917,NA,10010305,Confusional state,10037175,Psychiatric disorders,Psych,axicabtagene ciloleucel,DB13915
,3692733,DB13915,10043071,31,436,45,649,0.904430306,1.02542285,0.616793503,1.685990301,0.957532637,DB1391510043071_,0.043395473,0.025105064,NA,10043071,Tachycardia,10007541,Cardiac disorders,Card,axicabtagene ciloleucel,DB13915
,3733666,DB13915,10021143,27,440,34,660,0.50591555,1.190987413,0.680660078,2.065933269,0.666733027,DB1391510021143_,0.405365573,0.174782722,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,axicabtagene ciloleucel,DB13915
,3742847,DB00448,10077512,148,4997,154,2970,2.13990636873316e-06,0.571265721,0.450599841,0.723992969,2.81307521391103e-05,DB0044810077512_,10.4786472,-0.559900817,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,lansoprazole,DB00448
,3759669,DB00373,10066901,462,1370,335,952,0.616985874,0.958310277,0.811504164,1.132358987,0.758073842,DB0037310066901_,0.276974482,-0.042583673,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,timolol,DB00373
,3760358,DB12023,10011224,48,1065,14,493,0.162062827,1.586709024,0.850644024,3.147050104,0.300114232,DB1202310011224_,1.203592104,0.461662075,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,benralizumab,DB12023
,3784998,DB00019,10077040,41,18971,21,9508,1,0.978492308,0.564617956,1.74395201,1,DB0001910077040_,0,-0.021742353,NA,10077040,Wrong technique in device usage process,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,3799062,DB09303,10078390,49,26182,32,18927,0.735600544,1.106968151,0.694531916,1.786733743,0.847238699,DB0930310078390_,0.165772807,0.101624883,NA,10078390,Incorrect disposal of product,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,3800848,DB12023,10033371,37,1076,16,491,1,1.055204067,0.56630575,2.052339848,1,DB1202310033371_,0,0.053734176,NA,10033371,Pain,10018065,General disorders and administration site conditions,Genrl,benralizumab,DB12023
,3832780,DB12023,10047924,50,1063,15,492,0.17216142,1.542423456,0.842258152,2.987635184,0.313687989,DB1202310047924_,1.159356453,0.433354852,NA,10047924,Wheezing,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,benralizumab,DB12023
,3838950,DB00230,10079317,51,19623,18,8633,0.513002558,1.2464727,0.715477277,2.268528879,0.673086193,DB0023010079317_,0.395881885,0.220317722,NA,10079317,Drug effective for unapproved indication,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,3843279,DB13915,10041349,24,443,34,660,0.891100253,1.051585954,0.587944677,1.854477761,0.954795677,DB1391510041349_,0.046257912,0.050299457,NA,10041349,Somnolence,10029205,Nervous system disorders,Nerv,axicabtagene ciloleucel,DB13915
,3883301,DB06637,10069326,61,6101,40,1979,0.001007731,0.494699099,0.32551569,0.759214767,0.00553973,DB0663710069326_,5.195809592,-0.703805582,NA,10069326,Product substitution issue,10077536,Product issues,Prod,dalfampridine,DB06637
,3887342,DB00019,10078390,92,18920,48,9481,0.857479037,0.960476028,0.669774175,1.392803491,0.93170338,DB0001910078390_,0.070740776,-0.040326255,NA,10078390,Incorrect disposal of product,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,3899011,DB12023,10003239,41,1072,29,478,0.065811197,0.63059322,0.377418173,1.065783312,0.15380522,DB1202310003239_,1.872068282,-0.461094283,NA,10003239,Arthralgia,10028395,Musculoskeletal and connective tissue disorders,Musc,benralizumab,DB12023
,3915115,DB12023,10013709,61,1052,27,480,1,1.030822425,0.636012901,1.709669974,1,DB1202310013709_,0,0.030356955,NA,10013709,Drug ineffective,10018065,General disorders and administration site conditions,Genrl,benralizumab,DB12023
,3931930,DB11799,10028813,17,343,39,862,0.763090555,1.095376795,0.572819959,2.013963701,0.868793487,DB1179910028813_,0.140649826,0.091098409,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,bictegravir,DB11799
,3951137,DB12023,10037844,68,1045,22,485,0.16160712,1.434237488,0.863495795,2.466906579,0.299597499,DB1202310037844_,1.205315375,0.360633341,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,benralizumab,DB12023
,3969551,DB13915,10019211,25,442,30,664,0.481478327,1.251626062,0.695620314,2.234622421,0.646092395,DB1391510019211_,0.436812759,0.224443556,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,axicabtagene ciloleucel,DB13915
,3981348,DB11799,10037844,9,351,45,856,0.063175396,0.487985561,0.20745182,1.024819761,0.149267208,DB1179910037844_,1.902017234,-0.717469463,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,bictegravir,DB11799
,3999397,DB11799,10019211,26,334,34,867,0.012413664,1.983896203,1.124511638,3.463833419,0.042285123,DB1179910019211_,3.163319951,0.68506269,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,bictegravir,DB11799
,4025363,DB12023,10046735,47,1066,21,486,1,1.020357601,0.590439952,1.81790838,1,DB1202310046735_,0,0.020153156,NA,10046735,Urticaria,10040785,Skin and subcutaneous tissue disorders,Skin,benralizumab,DB12023
,4107519,DB11799,10047899,37,323,70,831,0.147696429,1.359549411,0.868596865,2.100058374,0.280794223,DB1179910047899_,1.270133179,0.307153329,NA,10047899,Weight increased,10022891,Investigations,Inv,bictegravir,DB11799
,4111694,DB00921,10022062,30,5815,46,4857,0.010632438,0.544768531,0.331490914,0.883225537,0.037375278,DB0092110022062_,3.286745812,-0.607394288,NA,10022062,Injection site extravasation,10018065,General disorders and administration site conditions,Genrl,buprenorphine,DB00921
,4113152,DB13928,10028813,181,760,247,798,0.018739159,0.769538274,0.61597311,0.960193604,0.058700847,DB1392810028813_,2.83530113,-0.261964588,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,semaglutide,DB13928
,4113153,DB13928,10061428,15,926,40,1005,0.002432515,0.40719096,0.207488829,0.759301068,0.011412521,DB1392810061428_,4.473044152,-0.898473014,NA,10061428,Decreased appetite,10027433,Metabolism and nutrition disorders,Metab,semaglutide,DB13928
,4115185,DB13928,10012735,60,881,141,904,1.41846206236184e-07,0.436813808,0.312815573,0.604073261,2.4939314588081e-06,DB1392810012735_,12.90165019,-0.828248244,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,semaglutide,DB13928
,4115186,DB13928,10053762,42,899,23,1022,0.005250962,2.075196178,1.208973243,3.644910845,0.021271128,DB1392810053762_,3.850404622,0.730055693,NA,10053762,Off label use,10022117,"Injury, poisoning and procedural complications",Inj&P,semaglutide,DB13928
,4115203,DB13928,10047700,109,832,206,839,7.71737528736457e-07,0.533749675,0.411004212,0.690371376,1.13897366326995e-05,DB1392810047700_,11.3827979,-0.627828324,NA,10047700,Vomiting,10017947,Gastrointestinal disorders,Gastr,semaglutide,DB13928
,4137381,DB13928,10047895,34,907,43,1002,0.641791356,0.87357574,0.535167718,1.416097604,0.778400046,DB1392810047895_,0.250514689,-0.135160445,NA,10047895,Weight decreased,10022891,Investigations,Inv,semaglutide,DB13928
,4142313,DB13928,10000081,40,901,47,998,0.826713346,0.942697207,0.596448695,1.483820616,0.908603458,DB1392810000081_,0.095846519,-0.059010143,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,semaglutide,DB13928
,4145572,DB00203,10080714,65,13813,26,8912,0.040731506,1.612939858,1.008273924,2.65115921,0.10710451,DB0020310080714_,2.233950189,0.478058513,NA,10080714,Vascular device infection,10021881,Infections and infestations,Infec,sildenafil,DB00203
,4145573,DB00374,10080714,184,17532,42,5682,0.042814764,1.419790964,1.009275269,2.038420357,0.111336177,DB0037410080714_,2.195201031,0.350509652,NA,10080714,Vascular device infection,10021881,Infections and infestations,Infec,treprostinil,DB00374
,4148505,DB13928,10010774,20,921,55,990,0.000225615,0.391022727,0.22020731,0.669021762,0.001594591,DB1392810010774_,6.441138079,-0.938989595,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,semaglutide,DB13928
,4150206,DB13928,10033645,81,860,85,960,0.745515834,1.063685441,0.763655557,1.480800523,0.854763634,DB1392810033645_,0.1569303,0.061739709,NA,10033645,Pancreatitis,10017947,Gastrointestinal disorders,Gastr,semaglutide,DB13928
,4160267,DB13928,10019211,42,899,21,1024,0.001976403,2.277178263,1.307108608,4.0800216,0.009634867,DB1392810019211_,4.642366772,0.822937073,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,semaglutide,DB13928
,4209956,DB13915,10016256,22,445,30,664,0.773553341,1.094145481,0.593087956,1.990015732,0.876340383,DB1391510016256_,0.132000699,0.089973676,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,axicabtagene ciloleucel,DB13915
,4215163,DB08889,10079213,29,3136,46,3839,0.295228368,0.7717887,0.46636597,1.258329633,0.461174359,DB0888910079213_,0.773979088,-0.259044471,NA,10079213,Intercepted product preparation error,10022117,"Injury, poisoning and procedural complications",Inj&P,carfilzomib,DB08889
,4217969,DB09303,10080648,182,26049,124,18835,0.642116514,1.061275248,0.839397761,1.345419674,0.778632739,DB0930310080648_,0.250215796,0.059471249,NA,10080648,Drug dose omission by device,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,4226041,DB12001,10011906,75,1551,6,50,0.048901187,0.403288788,0.16550103,1.187535302,0.122919354,DB1200110011906_,2.096226793,-0.908102378,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,abemaciclib,DB12001
,4226524,DB00479,10013952,54,561,8,391,3.38638115628682e-06,4.698917767,2.190289058,11.56378089,4.1997452686079e-05,DB0047910013952_,10.07790159,1.54733222,female,10013952,Dysphonia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,amikacin,DB00479
,4257638,DB00005,10080359,40,128042,24,42395,0.02877055,0.551850631,0.324621569,0.957103113,0.08196829,DB0000510080359_,2.501422819,-0.594477865,NA,10080359,Product dispensing error,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,4268752,DB11362,10060933,122,6361,53,2116,0.112832604,0.765752677,0.548105977,1.082308468,0.230326952,DB1136210060933_,1.46825545,-0.266896037,NA,10060933,Adverse event,10018065,General disorders and administration site conditions,Genrl,selexipag,DB11362
,4276016,DB08904,10071406,97,11513,18,3541,0.046947845,1.657338858,0.993730596,2.917734497,0.119356234,DB0890410071406_,2.125642695,0.505213218,NA,10071406,Maternal exposure before pregnancy,10022117,"Injury, poisoning and procedural complications",Inj&P,certolizumab pegol,DB08904
,4305579,DB00047,10079315,139,9146,102,8416,0.09134297,1.253958013,0.962464426,1.638275099,0.197430308,DB0004710079315_,1.622369627,0.226304959,NA,10079315,Device operational issue,10077536,Product issues,Prod,insulin glargine,DB00047
,4316177,DB00005,10080648,280,127802,63,42356,0.004823819,1.472936584,1.116910478,1.968570741,0.019892388,DB0000510080648_,3.917418126,0.387258084,NA,10080648,Drug dose omission by device,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,4421421,DB13928,10037844,30,911,32,1013,0.897739572,1.042462317,0.606639625,1.787061388,0.956338178,DB1392810037844_,0.044643686,0.041585527,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,semaglutide,DB13928
,4429516,DB00007,10079213,8,1939,344,4108,8.4085242424666e-45,0.049281013,0.021058048,0.098494416,3.98230738222044e-42,DB0000710079213_,95.32671251,-3.010216408,male,10079213,Intercepted product preparation error,10022117,"Injury, poisoning and procedural complications",Inj&P,leuprolide,DB00007
,4440205,DB09029,10080359,55,11289,25,7245,0.16869391,1.411879913,0.864185617,2.366818728,0.309094798,DB0902910080359_,1.17410726,0.344922088,NA,10080359,Product dispensing error,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,4506169,DB00921,10022076,21,5824,49,4854,5.20549494983983e-05,0.357224135,0.203188835,0.607916876,0.000457002,DB0092110022076_,7.690822528,-1.029391864,male,10022076,Injection site infection,10021881,Infections and infestations,Infec,buprenorphine,DB00921
,4510198,DB09302,10080648,52,2146,33,1514,0.657774301,1.111693955,0.701279779,1.784613136,0.790833505,DB0930210080648_,0.23466782,0.105884938,NA,10080648,Drug dose omission by device,10022117,"Injury, poisoning and procedural complications",Inj&P,alirocumab,DB09302
,4511096,DB09303,10084406,335,25896,224,18735,0.388462676,1.081992876,0.909889406,1.288606613,0.558452277,DB0930310084406_,0.582586113,0.078804596,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,4511333,DB00451,10084406,699,46572,207,15212,0.228431307,1.10297902,0.942127397,1.295764829,0.383949482,DB0045110084406_,0.957244293,0.098014719,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,4511377,DB00005,10084406,814,127268,305,42114,0.066018639,0.883159889,0.772930768,1.01114676,0.154187208,DB0000510084406_,1.869587781,-0.12424902,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,4511697,DB00476,10081572,39,17218,17,6160,0.543344651,0.820737359,0.453183785,1.548528757,0.698582183,DB0047610081572_,0.358702451,-0.197552124,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,4511698,DB01255,10081572,34,2099,17,1561,0.201015031,1.487219973,0.804697271,2.849648694,0.350202491,DB0125510081572_,1.049243746,0.396908587,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,lisdexamfetamine,DB01255
,4511738,DB00704,10081576,27,4329,49,5145,0.083125328,0.654915477,0.392871869,1.070599927,0.183640045,DB0070410081576_,1.694777714,-0.423249094,NA,10081576,Product administration error,10022117,"Injury, poisoning and procedural complications",Inj&P,naltrexone,DB00704
,4511876,DB00734,10084406,97,3953,158,4744,0.021416388,0.736797013,0.564130727,0.958301656,0.065271003,DB0073410084406_,2.729207402,-0.305442848,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,4511956,DB00758,10084406,107,8193,100,9974,0.067602865,1.302569929,0.980816055,1.731076672,0.157022164,DB0075810084406_,1.851368311,0.264339182,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,clopidogrel,DB00758
,4512085,DB08895,10084406,494,27620,111,6535,0.676492965,1.053013287,0.853819077,1.308047727,0.80384645,DB0889510084406_,0.21834701,0.051655851,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tofacitinib,DB08895
,4512158,DB00983,10084406,127,3374,58,1682,0.633726752,1.091572764,0.789297863,1.524743579,0.772217685,DB0098310084406_,0.258488794,0.087619559,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,formoterol,DB00983
,4512195,DB09029,10084406,249,11095,179,7091,0.249008982,0.889058594,0.728979361,1.085982079,0.408431857,DB0902910084406_,0.895430192,-0.117592136,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,4512226,DB00068,10084406,80,2154,24,641,1,0.991955584,0.615832587,1.651665592,1,DB0006810084406_,0,-0.008076947,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,interferon beta-1b,DB00068
,4512247,DB00264,10081572,135,29472,77,24815,0.006928291,1.476194801,1.107055409,1.980355461,0.026587363,DB0026410081572_,3.627319261,0.389467696,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,4512249,DB00451,10081572,141,47130,35,15384,0.160871386,1.314972825,0.902277717,1.963512816,0.298675923,DB0045110081572_,1.208396163,0.273816,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,levothyroxine,DB00451
,4512253,DB01076,10081572,71,25676,60,25523,0.38206474,1.176277067,0.821970082,1.6881578,0.552169216,DB0107610081572_,0.593900729,0.162354423,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,4512254,DB01104,10081572,50,15413,14,7272,0.106351106,1.684999021,0.916360525,3.302851974,0.220698647,DB0110410081572_,1.510957097,0.521764983,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,4512255,DB09292,10081572,45,4484,49,8213,0.012729925,1.682106642,1.094897502,2.578576902,0.04315827,DB0929210081572_,3.142881222,0.520046961,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,sacubitril,DB09292
,4512265,DB09292,10081770,24,4505,78,8184,0.012281397,0.558991974,0.337713037,0.894579929,0.041929669,DB0929210081770_,3.1717616,-0.581620163,NA,10081770,Product prescribing error,10022117,"Injury, poisoning and procedural complications",Inj&P,sacubitril,DB09292
,4512376,DB00864,10084406,47,6822,38,8354,0.062922019,1.514536223,0.965353918,2.390076932,0.148806088,DB0086410084406_,1.905111243,0.415109269,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tacrolimus,DB00864
,4512566,DB00019,10084406,273,18739,155,9374,0.215386307,0.881077705,0.719647844,1.081873295,0.367869232,DB0001910084406_,1.000027751,-0.126609456,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,4512579,DB05676,10084406,2271,44858,1215,24114,0.913030206,1.004778177,0.935088863,1.080062083,0.961085319,DB0567610084406_,0.039692092,0.004766798,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,apremilast,DB05676
,4513036,DB00563,10084406,353,46293,89,15259,0.023329764,1.307341879,1.032641165,1.66999213,0.069637416,DB0056310084406_,2.664453264,0.267995976,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,4513127,DB00188,10084406,74,7812,51,8777,0.008847213,1.630153103,1.124203765,2.379925517,0.032272694,DB0018810084406_,3.433533794,0.488673939,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,bortezomib,DB00188
,4513128,DB00399,10084406,51,6941,40,4958,0.67057292,0.910748566,0.589217477,1.416422271,0.800145684,DB0039910084406_,0.222961462,-0.093488418,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,zoledronic acid,DB00399
,4513129,DB00480,10084406,780,66648,621,67041,1.50604127941699e-05,1.263439814,1.134941298,1.406922304,0.000155488,DB0048010084406_,8.768940255,0.233838012,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,4513130,DB00863,10084406,153,10520,56,5784,0.008709128,1.502124195,1.097192877,2.082112399,0.03188737,DB0086310084406_,3.445545278,0.406880237,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ranitidine,DB00863
,4513131,DB00959,10084406,61,8017,30,4972,0.330819195,1.260990392,0.800562616,2.025623742,0.499530809,DB0095910084406_,0.694086004,0.231897438,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,methylprednisolone,DB00959
,4513132,DB01050,10084406,227,17881,89,9282,0.027073541,1.324000734,1.030332411,1.713655849,0.078192289,DB0105010084406_,2.54858424,0.280658012,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,4513133,DB06724,10084406,99,7830,35,3884,0.096223193,1.403049273,0.94346118,2.130471822,0.205053033,DB0672410084406_,1.584486637,0.33864792,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium carbonate,DB06724
,4513248,DB09029,10081202,34,11310,20,7250,0.889061728,1.08975307,0.609006252,1.999541619,0.953955749,DB0902910081202_,0.047137994,0.085951129,NA,10081202,Incorrect route of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,4513766,DB13879,10084406,41,2544,35,2783,0.299544855,1.281416419,0.793441772,2.079530262,0.465545396,DB1387910084406_,0.764545666,0.247966044,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,glecaprevir,DB13879
,4514063,DB00879,10084406,10,1767,43,3669,0.038237825,0.482938962,0.215865719,0.978867131,0.102100898,DB0087910084406_,2.281793759,-0.727865005,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,emtricitabine,DB00879
,4514250,DB00471,10084406,253,13936,76,5389,0.054577579,1.287252648,0.99039083,1.689565522,0.13359144,DB0047110084406_,2.012969093,0.252510217,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,montelukast,DB00471
,4514332,DB00480,10058818,23,67405,34,67628,0.184795334,0.678713873,0.38168643,1.186466885,0.329910844,DB0048010058818_,1.10893283,-0.387555634,NA,10058818,Skin laceration,10022117,"Injury, poisoning and procedural complications",Inj&P,lenalidomide,DB00480
,4514354,DB09302,10084406,106,2092,52,1495,0.031622883,1.456597147,1.028249113,2.08515105,0.0882758,DB0930210084406_,2.42728927,0.376102994,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,alirocumab,DB09302
,4514389,DB00158,10081572,39,16776,22,8082,0.584693268,0.854044523,0.493614271,1.513341991,0.732381641,DB0015810081572_,0.311453533,-0.157771951,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,4514391,DB00563,10081572,45,46601,26,15322,0.02688762,0.569068096,0.343491109,0.961150088,0.077767459,DB0056310081572_,2.554032205,-0.563755176,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,methotrexate,DB00563
,4514395,DB05676,10081572,64,47065,36,25293,0.834193486,0.955396978,0.625300972,1.480265373,0.913920298,DB0567610081572_,0.090011913,-0.045628341,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,apremilast,DB05676
,4514613,DB00264,10084406,403,29204,241,24651,2.37346268055931e-05,1.411486025,1.199165889,1.664235725,0.000231104,DB0026410084406_,8.372643666,0.344643068,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,metoprolol,DB00264
,4514614,DB00682,10084406,200,19259,97,16267,5.95406797136969e-06,1.74150315,1.358519916,2.245156145,6.88377728733021e-05,DB0068210084406_,9.583757939,0.55474862,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,warfarin,DB00682
,4514615,DB01097,10084406,57,6208,22,1481,0.062240553,0.618140097,0.370605673,1.065511181,0.147632805,DB0109710084406_,1.913027133,-0.481040153,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,leflunomide,DB01097
,4514616,DB01098,10084406,130,8019,92,7117,0.104107898,1.254080309,0.950894148,1.659525672,0.217215122,DB0109810084406_,1.526867072,0.226402483,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,rosuvastatin,DB01098
,4514618,DB06674,10084406,99,4407,43,1447,0.140184308,0.755986226,0.520611057,1.113751682,0.270112857,DB0667410084406_,1.30891542,-0.279732123,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,golimumab,DB06674
,4515446,DB00381,10084406,420,28940,266,22621,0.007514943,1.234181171,1.054848784,1.446001222,0.028340067,DB0038110084406_,3.563478669,0.210407731,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,4515640,DB00331,10084406,409,24537,244,20508,3.12870210554036e-05,1.40097799,1.191298506,1.650335447,0.00029439,DB0033110084406_,8.130604065,0.337170557,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,4515643,DB01306,10084406,63,4145,34,3832,0.013727021,1.71290222,1.108618661,2.687868867,0.045820653,DB0130610084406_,3.083020345,0.538189136,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin aspart,DB01306
,4515836,DB00484,10084406,42,2465,33,1747,0.72312627,0.902033001,0.555665012,1.475344052,0.837158089,DB0048410084406_,0.177742351,-0.103104173,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,brimonidine,DB00484
,4515918,DB05679,10084406,238,6693,166,4743,0.918173322,1.016016937,0.826824691,1.250808805,0.963748334,DB0567910084406_,0.036925083,0.015890019,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ustekinumab,DB05679
,4516038,DB06637,10084406,51,6111,20,1999,0.490592277,0.834137458,0.487254671,1.480946189,0.653849407,DB0663710084406_,0.424878219,-0.181357072,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,dalfampridine,DB06637
,4516039,DB08908,10084406,146,10527,39,3240,0.485197604,1.15218879,0.802453413,1.689261714,0.649294858,DB0890810084406_,0.431868338,0.141663429,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,dimethyl fumarate,DB08908
,4516904,DB00281,10084406,75,11383,26,5645,0.137172669,1.430495871,0.903718148,2.331570547,0.265771099,DB0028110084406_,1.325119871,0.358021147,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lidocaine,DB00281
,4516905,DB00813,10084406,50,10522,26,10142,0.011074115,1.853562407,1.131044215,3.104450109,0.038600659,DB0081310084406_,3.254485932,0.617109413,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,4517072,DB00497,10081572,36,19231,15,16360,0.023519663,2.041623612,1.089757918,4.015259129,0.070100276,DB0049710081572_,2.657828549,0.71374538,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,4517138,DB00019,10081572,56,18956,38,9491,0.154920379,0.737832001,0.479726903,1.145913886,0.290676148,DB0001910081572_,1.235545525,-0.304039121,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,4517225,DB00374,10084406,271,17445,64,5660,0.024749913,1.373796948,1.040889267,1.836508644,0.072948133,DB0037410084406_,2.618006592,0.317578401,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,treprostinil,DB00374
,4517620,DB00136,10084406,33,2059,23,1659,0.684962183,1.155998282,0.65570892,2.07051337,0.809706594,DB0013610084406_,0.211083327,0.144964284,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,calcitriol,DB00136
,4517621,DB05259,10084406,108,11162,16,2712,0.068035245,1.639961261,0.963399595,2.976486703,0.157762247,DB0525910084406_,1.846666148,0.49467262,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,glatiramer,DB05259
,4517855,DB01224,10081572,31,8077,23,5894,1,0.983541204,0.554568802,1.768285243,1,DB0122410081572_,0,-0.016595747,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,4517856,DB01267,10081572,43,2809,72,3643,0.217181243,0.774569408,0.516412989,1.149704224,0.370112096,DB0126710081572_,0.993949356,-0.255448006,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,paliperidone,DB01267
,4517858,DB01224,10084406,86,8022,74,5843,0.296564775,0.846499795,0.611962936,1.173390841,0.462413408,DB0122410084406_,0.771295965,-0.16664532,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,quetiapine,DB01224
,4517859,DB01267,10084406,76,2776,129,3586,0.063046305,0.761084495,0.563011462,1.022952699,0.149049539,DB0126710084406_,1.90347655,-0.273010895,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,paliperidone,DB01267
,4518590,DB01281,10084406,100,8832,12,1786,0.097469795,1.685081849,0.920663714,3.377714275,0.207071616,DB0128110084406_,1.574690576,0.521814137,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,abatacept,DB01281
,4518651,DB06262,10084406,79,3721,71,4243,0.160459597,1.268724927,0.906153802,1.779224843,0.298111429,DB0626210084406_,1.210287939,0.238012402,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,droxidopa,DB06262
,4519096,DB05829,10081572,87,1519,10,199,0.869953927,1.139657998,0.578444357,2.501423853,0.942182195,DB0582910081572_,0.05955661,0.130728216,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,parathyroid hormone,DB05829
,4519125,DB00005,10081572,81,128001,30,42389,0.584129799,0.894123411,0.581454534,1.408761288,0.732007236,DB0000510081572_,0.31196488,-0.11191147,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,etanercept,DB00005
,4519128,DB06643,10081572,77,52344,13,7502,0.526616971,0.848910708,0.468006583,1.666870694,0.68437294,DB0664310081572_,0.379252275,-0.163801272,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,4519527,DB00230,10084406,273,19401,91,8560,0.021840898,1.323582133,1.03890302,1.699471976,0.066257488,DB0023010084406_,2.714206798,0.280341798,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,4519987,DB01611,10084406,141,11772,20,2341,0.166758069,1.401942034,0.87203168,2.370110477,0.306477126,DB0161110084406_,1.182612158,0.337858442,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxychloroquine,DB01611
,4520211,DB06643,10084406,107,52314,15,7500,1,1.022671419,0.592664343,1.891890916,1,DB0664310084406_,0,0.022418242,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,4520784,DB00722,10084406,326,25077,242,25790,0.000141819,1.385393706,1.16842219,1.644458302,0.001075265,DB0072210084406_,6.835187697,0.325984363,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,4520839,DB00338,10084406,486,33188,238,22034,0.000111618,1.355717007,1.157453231,1.591378583,0.000876832,DB0033810084406_,7.039195249,0.304330471,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,4520840,DB00788,10084406,109,9247,52,5009,0.506664539,1.135443502,0.807247084,1.614936796,0.667372248,DB0078810084406_,0.404407296,0.127023326,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,naproxen,DB00788
,4520841,DB01062,10084406,52,4434,17,1728,0.591498871,1.192031195,0.676002682,2.205281762,0.737822975,DB0106210084406_,0.304051354,0.175658739,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,oxybutynin,DB01062
,4520991,DB00455,10084406,124,9277,49,5069,0.055064231,1.382709997,0.983878324,1.969825596,0.134463331,DB0045510084406_,2.006463746,0.324045339,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,loratadine,DB00455
,4520992,DB00668,10084406,38,10053,17,4286,0.883030256,0.952997153,0.524361404,1.802697882,0.951111532,DB0066810084406_,0.050123944,-0.048143362,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,epinephrine,DB00668
,4520994,DB14512,10084406,207,4637,113,2299,0.430351197,0.908240725,0.71459065,1.159099397,0.598839385,DB1451210084406_,0.512761856,-0.09624582,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,mometasone furoate,DB14512
,4521081,DB13961,10084406,110,9347,68,6346,0.591036759,1.098290692,0.802968959,1.511315377,0.737498278,DB1396110084406_,0.304491526,0.093755055,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fish oil,DB13961
,4521147,DB09029,10081572,151,11193,92,7178,0.740871395,1.052560929,0.805410721,1.3818016,0.851295256,DB0902910081572_,0.160996259,0.051226175,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,4521272,DB00108,10084406,84,10110,17,3278,0.081085802,1.601993639,0.941772949,2.883350053,0.180217334,DB0010810084406_,1.713591745,0.471248878,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,natalizumab,DB00108
,4521815,DB01234,10084406,311,31314,226,32662,3.68570931014917e-05,1.435328424,1.204599062,1.712479233,0.000339986,DB0123410084406_,7.986607578,0.36139369,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,dexamethasone,DB01234
,4522017,DB11569,10084406,51,3434,32,2280,0.822585632,1.058165751,0.664763738,1.707160912,0.905733216,DB1156910084406_,0.09901048,0.056536985,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ixekizumab,DB11569
,4522028,DB00921,10081572,122,5723,83,4820,0.137889353,1.237929983,0.926397623,1.661002919,0.266766397,DB0092110081572_,1.321381921,0.213440616,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,buprenorphine,DB00921
,4522092,DB00571,10084406,61,5062,20,2589,0.097694587,1.559863753,0.925756732,2.735672069,0.2074416,DB0057110084406_,1.572905426,0.444598479,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,propranolol,DB00571
,4522093,DB01156,10084406,187,13435,54,6274,0.001666805,1.617130786,1.186945617,2.235268142,0.008376249,DB0115610084406_,4.782355119,0.480653459,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,bupropion,DB01156
,4522247,DB00364,10084406,45,2705,17,1383,0.343942239,1.353292008,0.756159691,2.532081944,0.513228597,DB0036410084406_,0.667033924,0.302540149,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sucralfate,DB00364
,4522248,DB00497,10084406,163,19104,97,16278,0.004933003,1.431816386,1.105815076,1.862277767,0.020252086,DB0049710084406_,3.899497459,0.358943838,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,oxycodone,DB00497
,4522250,DB00736,10084406,117,10474,51,5502,0.28905474,1.205059613,0.858740612,1.711864564,0.454183211,DB0073610084406_,0.789254613,0.186529037,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,esomeprazole,DB00736
,4522251,DB00996,10084406,494,38459,238,22187,0.022742382,1.197467289,1.02284686,1.404911887,0.0682869,DB0099610084406_,2.684037333,0.180208734,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,4522252,DB00999,10084406,334,21096,149,12090,0.011514869,1.284656197,1.054521329,1.571024188,0.039861493,DB0099910084406_,3.222344497,0.250491131,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,4522253,DB01076,10084406,459,25288,335,25248,1.45848031288544e-05,1.367968223,1.184339318,1.58134071,0.000151257,DB0107610084406_,8.796528398,0.31332659,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,atorvastatin,DB01076
,4522254,DB01136,10084406,135,9749,95,11020,0.000414412,1.606265955,1.224510449,2.114136928,0.002638124,DB0113610084406_,5.937687267,0.473912203,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,carvedilol,DB01136
,4522528,DB09107,10081572,79,1136,88,915,0.052074036,0.723196084,0.520073762,1.004260585,0.128940327,DB0910710081572_,2.048405567,-0.324074885,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,methoxy polyethylene glycol-epoetin beta,DB09107
,4523076,DB00316,10084406,656,64818,259,36694,6.08549614243838e-07,1.433844246,1.239135123,1.663115859,9.22072398422252e-06,DB0031610084406_,11.594057,0.360359121,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,4523077,DB00924,10084406,133,10029,45,4206,0.246772231,1.239474956,0.875993204,1.782545711,0.405857095,DB0092410084406_,0.901754165,0.214687868,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclobenzaprine,DB00924
,4523078,DB01068,10084406,181,13582,60,6780,0.005821926,1.505862238,1.116983557,2.054790253,0.023110975,DB0106810084406_,3.767447681,0.40936565,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,4523651,DB00065,10084406,58,9406,46,4911,0.038052049,0.658314597,0.438677154,0.993093396,0.10171851,DB0006510084406_,2.285545988,-0.418072351,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,infliximab,DB00065
,4523729,DB00181,10084406,83,9773,37,5834,0.155389963,1.339081815,0.897276458,2.032545303,0.291359645,DB0018110084406_,1.233196883,0.291984167,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,baclofen,DB00181
,4523730,DB00413,10084406,40,2159,28,1179,0.369965256,0.78019975,0.466778053,1.320424583,0.539607511,DB0041310084406_,0.616913235,-0.248205303,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pramipexole,DB00413
,4523731,DB00476,10084406,240,17017,71,6106,0.173465802,1.212886929,0.925516905,1.606418658,0.315485114,DB0047610084406_,1.15364378,0.19300341,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,duloxetine,DB00476
,4523734,DB01592,10084406,109,6167,31,3036,0.006363152,1.730890516,1.149164507,2.676310715,0.024819029,DB0159210084406_,3.696144611,0.548636025,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,iron,DB01592
,4523816,DB00695,10084406,393,27656,196,20332,8.2147186170254e-06,1.474087673,1.23749534,1.760508911,9.15901925126247e-05,DB0069510084406_,9.298186361,0.388039271,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,4523817,DB06404,10084406,94,2975,31,869,0.58727728,0.885736761,0.57998622,1.385717557,0.734410928,DB0640410084406_,0.308686559,-0.121335482,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,human c1-esterase inhibitor,DB06404
,4524232,DB00016,10084406,33,2729,25,2265,0.791506738,1.095581689,0.629840048,1.927854017,0.887196359,DB0001610084406_,0.119688947,0.091285445,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,erythropoietin,DB00016
,4524974,DB00051,10084406,139,25592,51,11369,0.269883871,1.210750396,0.871789681,1.704717941,0.43251517,DB0005110084406_,0.838137878,0.191240329,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,adalimumab,DB00051
,4525015,DB00820,10084406,245,11670,91,5725,0.025669039,1.320790571,1.031922998,1.702740441,0.074980351,DB0082010084406_,2.590529187,0.278230475,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tadalafil,DB00820
,4525379,DB00207,10084406,118,8962,50,5405,0.037238118,1.423287456,1.012343362,2.026653791,0.100031062,DB0020710084406_,2.302274525,0.352969306,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,azithromycin,DB00207
,4525380,DB00787,10084406,225,16775,169,17079,0.003244122,1.355470641,1.104076522,1.666698344,0.014417405,DB0078710084406_,4.239319134,0.30414873,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,acyclovir,DB00787
,4525381,DB01039,10084406,41,2932,41,3010,0.912006971,1.026604169,0.64733824,1.62812687,0.96056931,DB0103910084406_,0.040229139,0.026256432,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fenofibrate,DB01039
,4525382,DB08910,10084406,174,16570,158,17330,0.204873691,1.151770663,0.922197392,1.43931186,0.35491366,DB0891010084406_,1.035880729,0.141300465,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pomalidomide,DB08910
,4525612,DB09303,10081572,88,26143,67,18892,0.74512551,0.949164525,0.682529024,1.32513453,0.854485157,DB0930310081572_,0.157256147,-0.052173129,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,evolocumab,DB09303
,4525843,DB00193,10084406,255,19065,59,8643,1.07730218940043e-06,1.95932628,1.469189286,2.649937078,1.52775225510603e-05,DB0019310084406_,11.08912792,0.672600679,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tramadol,DB00193
,4525845,DB00761,10084406,204,15103,75,8550,0.001337858,1.539800062,1.174509112,2.03695748,0.006996734,DB0076110084406_,4.962311793,0.431652578,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium chloride,DB00761
,4525846,DB00904,10084406,295,22774,74,14382,2.4336676160378e-14,2.517439617,1.943296566,3.296954453,1.35671162858014e-12,DB0090410084406_,27.32595726,0.92324236,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,4525847,DB00905,10084406,33,2685,22,903,0.018116427,0.504555398,0.283823976,0.913562147,0.057130473,DB0090510084406_,2.862417619,-0.684077637,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,bimatoprost,DB00905
,4525848,DB01222,10084406,140,9134,67,5338,0.191826401,1.221096922,0.90442072,1.662660554,0.338934356,DB0122210084406_,1.08194883,0.199749571,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,budesonide,DB01222
,4525850,DB08893,10084406,34,2051,24,1034,0.209770418,0.714258724,0.408852413,1.266170058,0.360887223,DB0889310084406_,1.019189772,-0.336510024,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,mirabegron,DB08893
,4525908,DB00177,10084406,46,4754,22,2828,0.450870051,1.243743056,0.731392439,2.175771757,0.618518269,DB0017710084406_,0.48042855,0.218125427,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,valsartan,DB00177
,4526059,DB05316,10081572,72,4284,79,6916,0.022608777,1.471234635,1.051470208,2.055893083,0.06798576,DB0531610081572_,2.688457004,0.386101936,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,pimavanserin,DB05316
,4526145,DB00338,10081572,75,33599,40,22232,0.294861635,1.240640766,0.834078349,1.870144436,0.460787044,DB0033810081572_,0.774819286,0.215627993,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,omeprazole,DB00338
,4526150,DB00999,10081572,51,21379,23,12216,0.397659918,1.267040025,0.759949098,2.173373316,0.567391757,DB0099910081572_,0.566705284,0.236683491,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrochlorothiazide,DB00999
,4527076,DB00182,10084406,64,5130,23,2829,0.090508469,1.534426508,0.937269036,2.595842409,0.196053821,DB0018210084406_,1.629366059,0.428156701,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,amphetamine,DB00182
,4527077,DB00404,10084406,245,19647,67,9795,6.84458335776817e-06,1.823020358,1.384497486,2.428603506,7.78830621467257e-05,DB0040410084406_,9.460302059,0.600494663,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,4528365,DB00175,10084406,126,8005,59,6047,0.002687019,1.613178842,1.172769025,2.241007282,0.012362731,DB0017510084406_,4.393068867,0.478206668,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pravastatin,DB00175
,4528538,DB00343,10084406,125,8611,35,5060,4.87929274864825e-05,2.098541321,1.429918128,3.151764277,0.000432919,DB0034310084406_,7.744960256,0.741242494,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,diltiazem,DB00343
,4528539,DB01240,10084406,50,5701,20,1556,0.146001701,0.682376298,0.3976092,1.213943301,0.278444021,DB0124010084406_,1.278538242,-0.382174017,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,epoprostenol,DB01240
,4528542,DB09029,10081770,33,11311,24,7246,0.683937341,0.880854855,0.50459838,1.558864353,0.808956803,DB0902910081770_,0.212009759,-0.126862417,NA,10081770,Product prescribing error,10022117,"Injury, poisoning and procedural complications",Inj&P,secukinumab,DB09029
,4528593,DB00060,10084406,72,9436,15,2450,0.506911864,1.246266193,0.706242105,2.34521665,0.667560728,DB0006010084406_,0.404124915,0.220152036,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,interferon beta-1a,DB00060
,4528595,DB00641,10084406,162,13962,119,12356,0.133033425,1.204744404,0.943784417,1.541422211,0.259983908,DB0064110084406_,1.34713554,0.186267432,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,4528596,DB00973,10084406,48,3803,47,2974,0.298457325,0.798683799,0.521325255,1.224257392,0.46444561,DB0097310084406_,0.766910822,-0.224790158,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ezetimibe,DB00973
,4528763,DB00186,10084406,179,16722,66,9942,0.000862285,1.612453409,1.208073393,2.1745876,0.004876324,DB0018610084406_,5.32336356,0.477756876,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lorazepam,DB00186
,4528765,DB00586,10084406,130,6979,42,2763,0.268170489,1.225372706,0.856632903,1.784395042,0.430622598,DB0058610084406_,0.842523215,0.203245047,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,diclofenac,DB00586
,4528766,DB00836,10084406,54,5481,20,4055,0.008917895,1.997388688,1.174091343,3.528582013,0.032477569,DB0083610084406_,3.427205601,0.691840672,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,loperamide,DB00836
,4528767,DB01075,10084406,109,19839,46,11051,0.130215919,1.319921176,0.926218647,1.907414932,0.25602913,DB0107510084406_,1.362464053,0.27757202,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,4528768,DB01104,10084406,208,15255,79,7207,0.111297529,1.243837516,0.954032841,1.635313543,0.228007915,DB0110410084406_,1.478374936,0.218201371,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sertraline,DB01104
,4528769,DB06228,10084406,162,15750,71,16005,9.39783551789333e-10,2.318682128,1.741990807,3.112046637,2.6264976777015e-08,DB0622810084406_,17.45502947,0.840998976,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,rivaroxaban,DB06228
,4528853,DB01373,10084406,256,22464,72,7309,0.30189569,1.156845479,0.886185398,1.52637186,0.468243831,DB0137310084406_,0.758766112,0.145696886,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,4529108,DB00321,10084406,80,7367,30,2820,1,1.020775606,0.661645533,1.612889858,1,DB0032110084406_,0,0.020562737,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,amitriptyline,DB00321
,4529245,DB09073,10084406,283,19977,9,781,0.643158079,1.229312059,0.635144445,2.726731267,0.779536122,DB0907310084406_,0.249056251,0.206454711,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,palbociclib,DB09073
,4529486,DB00203,10084406,297,13581,120,8818,9.82821414438423e-06,1.606957921,1.293355332,2.006929841,0.000107005,DB0020310084406_,9.142637961,0.474342901,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sildenafil,DB00203
,4530777,DB09570,10084406,74,3827,57,3878,0.134146917,1.315496175,0.915849856,1.898020655,0.261517078,DB0957010084406_,1.341255691,0.274213914,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ixazomib,DB09570
,4530871,DB01060,10084406,132,8455,52,5029,0.011255625,1.509823274,1.08526542,2.127360584,0.039126321,DB0106010084406_,3.24095988,0.411992607,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,amoxicillin,DB01060
,4530921,DB09331,10084406,21,2064,33,2396,0.336672099,0.738774576,0.404838318,1.320224693,0.505700555,DB0933110084406_,0.681810573,-0.302762443,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,daratumumab,DB09331
,4531087,DB00273,10084406,111,8370,25,2168,0.593884887,1.150034746,0.737700885,1.858047101,0.739928153,DB0027310084406_,0.301202187,0.139792156,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,topiramate,DB00273
,4531118,DB00588,10084406,210,16314,116,8352,0.517410566,0.926815613,0.734115198,1.17479368,0.677011062,DB0058810084406_,0.390067666,-0.076000641,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,4531613,DB00635,10081572,58,32995,27,23767,0.061823953,1.547342945,0.963966872,2.542275147,0.146816876,DB0063510081572_,1.91856921,0.436539231,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,4531614,DB01373,10081572,67,22653,12,7369,0.065557784,1.816140143,0.973610064,3.691381596,0.15341759,DB0137310081572_,1.874591732,0.596713448,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,calcium,DB01373
,4531691,DB00635,10084406,412,32641,187,23607,8.82372265286469e-08,1.593413879,1.336200547,1.90588827,1.61669374519974e-06,DB0063510084406_,13.33512739,0.465878808,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,prednisone,DB00635
,4531909,DB00047,10081572,158,9127,159,8359,0.427221671,0.910099169,0.724071647,1.143866282,0.595866112,DB0004710081572_,0.517739282,-0.094201709,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,4531939,DB01261,10084406,152,3629,106,3197,0.074997311,1.26321869,0.974568403,1.642201464,0.169815595,DB0126110084406_,1.773042168,0.23366298,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sitagliptin,DB01261
,4532052,DB08934,10084406,38,4451,50,6154,0.828954012,1.050749801,0.669266251,1.637833088,0.910150159,DB0893410084406_,0.094145683,0.049504006,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sofosbuvir,DB08934
,4532236,DB00158,10084406,302,16513,120,7984,0.074729999,1.216767745,0.979876855,1.518848956,0.169414866,DB0015810084406_,1.775404744,0.196197953,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,folic acid,DB00158
,4532237,DB00169,10084406,448,38243,182,17993,0.102527933,1.15811964,0.971782932,1.384882215,0.214805255,DB0016910084406_,1.538023454,0.14679769,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,4532671,DB00734,10081572,23,4027,38,4864,0.248070225,0.73109156,0.415079594,1.261430901,0.407443738,DB0073410081572_,0.897852423,-0.313216574,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,risperidone,DB00734
,4532768,DB00437,10084406,89,6832,113,11433,0.057267819,1.317977236,0.985275642,1.758587771,0.138315228,DB0043710084406_,1.978219938,0.276098164,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,allopurinol,DB00437
,4532769,DB08906,10084406,55,2138,25,1133,0.554633164,1.165785549,0.709895046,1.963593563,0.70812299,DB0890610084406_,0.345137486,0.153395151,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone furoate,DB08906
,4533226,DB00829,10084406,69,7983,27,4427,0.134702215,1.417154568,0.894698944,2.304194404,0.262202224,DB0082910084406_,1.338639226,0.348651036,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,diazepam,DB00829
,4533863,DB00448,10084406,47,5098,13,3111,0.01055419,2.206058983,1.171928156,4.451901458,0.037159853,DB0044810084406_,3.292526322,0.791207658,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lansoprazole,DB00448
,4533864,DB06403,10084406,158,21313,42,6619,0.404420763,1.168294606,0.825692663,1.685461293,0.574170885,DB0640310084406_,0.554828219,0.155545084,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ambrisentan,DB06403
,4533865,DB08931,10084406,143,6434,43,2403,0.24324297,1.242010955,0.874529608,1.795740915,0.401598032,DB0893110084406_,0.912303611,0.216731804,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,riociguat,DB08931
,4534299,DB00335,10084406,92,8374,42,5423,0.062208783,1.418517157,0.97284905,2.098681717,0.147584085,DB0033510084406_,1.913357197,0.34961207,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,atenolol,DB00335
,4535375,DB00741,10084406,52,4042,29,3145,0.176330228,1.395114136,0.867060381,2.285024402,0.319104963,DB0074110084406_,1.142235193,0.33297623,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocortisone,DB00741
,4535667,DB00620,10084406,82,4746,35,3097,0.036083356,1.528751825,1.01445415,2.346928425,0.097687817,DB0062010084406_,2.325978423,0.424451602,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,triamcinolone,DB00620
,4535668,DB11750,10084406,100,2400,56,1457,0.674011566,1.084068548,0.768534799,1.541998321,0.802282079,DB1175010084406_,0.220295013,0.080721138,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,clobetasol,DB11750
,4535769,DB00879,10080359,27,1750,61,3651,0.818563581,0.923452742,0.56213481,1.481156848,0.90321487,DB0087910080359_,0.101794803,-0.079635654,NA,10080359,Product dispensing error,10022117,"Injury, poisoning and procedural complications",Inj&P,emtricitabine,DB00879
,4536020,DB00433,10084406,72,7584,17,6003,9.00293313564154e-07,3.352048196,1.953033118,6.074345743,1.30597184034403e-05,DB0043310084406_,11.245978,1.209571561,female,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,prochlorperazine,DB00433
,4536058,DB00795,10084406,53,4516,18,1485,0.890402621,0.968227499,0.555953709,1.762190789,0.954638381,DB0079510084406_,0.046422669,-0.0322882,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sulfasalazine,DB00795
,4536059,DB08904,10084406,541,11069,165,3394,1,1.005348942,0.839245471,1.209327543,1,DB0890410084406_,0,0.005334687,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,certolizumab pegol,DB08904
,4536108,DB00316,10081770,39,65435,16,36937,0.326579991,1.375925131,0.751254271,2.637760299,0.495035038,DB0031610081770_,0.703126735,0.319126327,NA,10081770,Product prescribing error,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,4536375,DB00390,10084406,52,4093,18,3283,0.001542694,2.316894655,1.330148866,4.217032556,0.00787373,DB0039010084406_,4.844223366,0.840227778,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,digoxin,DB00390
,4536376,DB01069,10084406,70,6630,17,2378,0.178040112,1.476779695,0.857802132,2.68268855,0.321358581,DB0106910084406_,1.135197706,0.389863835,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,promethazine,DB01069
,4537906,DB00115,10084406,277,18148,124,10348,0.027893389,1.273763181,1.025497089,1.589407741,0.079993206,DB0011510084406_,2.525813567,0.241975654,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,4537907,DB00126,10084406,138,10033,70,5875,0.347754756,1.154423102,0.858089949,1.564927701,0.517319384,DB0012610084406_,0.659094832,0.143600741,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ascorbic acid,DB00126
,4537910,DB00927,10084406,88,7409,48,4968,0.291085703,1.229281796,0.853538757,1.78925333,0.456487543,DB0092710084406_,0.784193867,0.206430093,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,famotidine,DB00927
,4538152,DB00046,10084406,72,5387,41,4651,0.036625302,1.516105482,1.01703001,2.287201809,0.098829285,DB0004610084406_,2.314361311,0.416144864,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin lispro,DB00046
,4538154,DB00490,10084406,52,4018,24,1552,0.519639887,0.836951604,0.504707952,1.424906062,0.678779199,DB0049010084406_,0.387459391,-0.17798903,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,buspirone,DB00490
,4538155,DB00559,10084406,225,9434,54,3252,0.018034262,1.436216596,1.059853636,1.975987524,0.05693118,DB0055910084406_,2.865912113,0.362012292,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,bosentan,DB00559
,4538305,DB00669,10084406,152,6225,26,1071,1,1.005819561,0.656602269,1.597318004,1,DB0066910084406_,0,0.005802693,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sumatriptan,DB00669
,4538401,DB00316,10081572,134,65340,57,36896,0.082545116,1.327482848,0.966471663,1.843624456,0.182606587,DB0031610081572_,1.700421241,0.283284554,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,4538486,DB01137,10084406,60,7712,28,5565,0.064868946,1.54624152,0.970442605,2.519023748,0.152225717,DB0113710084406_,1.882390879,0.435827161,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,levofloxacin,DB01137
,4538524,DB00091,10084406,116,5394,25,2645,8.56501141658848e-05,2.275074819,1.46265289,3.668948216,0.000699104,DB0009110084406_,7.26571149,0.822012939,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cyclosporine,DB00091
,4538661,DB01409,10084406,70,5961,32,3934,0.103122638,1.443603184,0.935379376,2.271793502,0.215690183,DB0140910084406_,1.533912238,0.367142199,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tiotropium,DB01409
,4538874,DB00019,10076869,47,18965,28,9501,0.46417219,0.840939938,0.515457951,1.395460069,0.631313568,DB0001910076869_,0.459952602,-0.173235038,NA,10076869,Product preparation error,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,4538889,DB00047,10084406,219,9066,137,8381,0.000391344,1.477721614,1.185629727,1.847013891,0.002518108,DB0004710084406_,5.98424729,0.390501452,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin glargine,DB00047
,4538928,DB08880,10084406,35,3303,15,794,0.07121111,0.560996438,0.296819776,1.111373705,0.163401811,DB0888010084406_,1.811543012,-0.578040723,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,teriflunomide,DB08880
,4539168,DB00190,10084406,123,3174,174,4500,1,1.002216091,0.785400276,1.275766636,1,DB0019010084406_,0,0.002213639,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,carbidopa,DB00190
,4539204,DB00213,10084406,308,18587,134,13287,1.0734249055561e-06,1.643070113,1.335415962,2.030392586,1.52348669776146e-05,DB0021310084406_,11.09192388,0.496566512,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,4540040,DB00285,10084406,125,10826,32,3686,0.166578447,1.329943919,0.894068785,2.031061033,0.306232653,DB0028510084406_,1.183410163,0.285136775,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,venlafaxine,DB00285
,4540848,DB00254,10084406,82,5853,29,3359,0.028483962,1.622655196,1.048284827,2.576845212,0.08134831,DB0025410084406_,2.509015221,0.484063818,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,doxycycline,DB00254
,4540851,DB00654,10084406,60,3756,34,2564,0.399827822,1.20460882,0.775594844,1.898540249,0.569696398,DB0065410084406_,0.562651696,0.186154884,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,latanoprost,DB00654
,4540855,DB11089,10084406,112,10063,53,8354,0.000689035,1.754265969,1.252649766,2.483877951,0.004039903,DB1108910084406_,5.511534673,0.562050518,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,docusate,DB11089
,4541692,DB01068,10081572,38,13725,17,6823,0.775934181,1.111204003,0.611676048,2.101159374,0.877822795,DB0106810081572_,0.130310533,0.105444115,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,clonazepam,DB01068
,4541868,DB00153,10084406,99,7324,36,3403,0.226837619,1.277683247,0.862342557,1.931208495,0.381998707,DB0015310084406_,0.962338055,0.245048474,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ergocalciferol,DB00153
,4542078,DB01115,10084406,61,3539,25,2243,0.074088553,1.546350047,0.953070148,2.579070106,0.168359784,DB0111510084406_,1.781652016,0.435897345,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,nifedipine,DB01115
,4542079,DB08932,10084406,713,18730,197,6400,0.009298855,1.236682415,1.051900588,1.459293475,0.033574232,DB0893210084406_,3.393996403,0.212432322,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,4542080,DB11362,10084406,235,6248,54,2115,0.01053039,1.473026435,1.086838931,2.027225221,0.037095933,DB1136210084406_,3.294247931,0.387319084,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,selexipag,DB11362
,4542869,DB00678,10084406,262,15337,161,10563,0.272569577,1.120811681,0.916004332,1.374678135,0.435531388,DB0067810084406_,0.831188412,0.114053138,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,4543590,DB06168,10081572,39,570,30,370,0.525043822,0.844008755,0.50108932,1.43378126,0.683156046,DB0616810081572_,0.381031974,-0.169592412,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,canakinumab,DB06168
,4543765,DB00874,10084406,42,3293,17,1959,0.222598527,1.469647599,0.816229369,2.761629948,0.376710985,DB0087410084406_,0.976277004,0.385022643,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,guaifenesin,DB00874
,4544098,DB11834,10084406,81,861,62,726,0.599937217,1.101520789,0.769474431,1.583060056,0.744504497,DB1183410084406_,0.295036386,0.096691761,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,guselkumab,DB11834
,4545123,DB00169,10081572,71,38620,22,18153,0.09499448,1.516941547,0.92869867,2.571680296,0.203200677,DB0016910081572_,1.593561232,0.416696168,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,cholecalciferol,DB00169
,4545124,DB00213,10081572,41,18854,18,13403,0.08744934,1.619208726,0.909207368,2.995817817,0.190866553,DB0021310081572_,1.656180768,0.481937589,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,pantoprazole,DB00213
,4545127,DB00381,10081572,71,29289,49,22838,0.520938303,1.129805283,0.773813775,1.661454626,0.679934862,DB0038110081572_,0.385758277,0.122045302,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,amlodipine,DB00381
,4545128,DB00404,10081572,47,19845,16,9846,0.228001543,1.457409007,0.81105076,2.755082031,0.383393825,DB0040410081572_,0.958692555,0.376660207,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,alprazolam,DB00404
,4545132,DB00588,10081572,47,16477,20,8448,0.520891537,1.204845851,0.699659023,2.148199198,0.679924221,DB0058810081572_,0.385773926,0.186351634,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone propionate,DB00588
,4545133,DB00641,10081572,37,14087,32,12443,1,1.021313403,0.61860949,1.694652144,1,DB0064110081572_,0,0.021089449,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,simvastatin,DB00641
,4545135,DB00695,10081572,50,27999,38,20490,0.914093643,0.962890828,0.618692189,1.509593333,0.961536643,DB0069510081572_,0.039222604,-0.03781524,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,furosemide,DB00695
,4545324,DB00575,10084406,67,5177,42,3787,0.494847288,1.16688451,0.779866445,1.763635277,0.657228907,DB0057510084406_,0.419722909,0.154337385,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,clonidine,DB00575
,4545325,DB00956,10084406,59,5755,22,3445,0.064542716,1.605285725,0.966954428,2.756579914,0.151642931,DB0095610084406_,1.886226659,0.473301763,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydrocodone,DB00956
,4545581,DB00211,10084406,36,1400,26,1605,0.093889057,1.58710641,0.926821781,2.752343305,0.201582509,DB0021110084406_,1.601556508,0.46191249,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,midodrine,DB00211
,4546702,DB00472,10084406,128,10631,48,4264,0.737645208,1.069571092,0.760432313,1.526168423,0.848812708,DB0047210084406_,0.16391672,0.06725772,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fluoxetine,DB00472
,4546718,DB00555,10071583,53,6994,39,3447,0.059229602,0.669782116,0.433687859,1.042485819,0.142028928,DB0055510071583_,1.951724524,-0.400802819,NA,10071583,Haemophagocytic lymphohistiocytosis,10021428,Immune system disorders,Immun,lamotrigine,DB00555
,4546857,DB00215,10084406,124,10979,43,5233,0.080250275,1.374490754,0.962720213,1.995701885,0.178821505,DB0021510084406_,1.721367151,0.318083302,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,citalopram,DB00215
,4546858,DB00423,10084406,39,2428,15,1025,0.880882668,1.0975807,0.588468995,2.153201768,0.950123172,DB0042310084406_,0.051163648,0.093108394,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,methocarbamol,DB00423
,4546859,DB00425,10084406,138,12557,47,7437,0.000955709,1.738928666,1.238825335,2.479039034,0.005306466,DB0042510084406_,5.238829115,0.553269214,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,zolpidem,DB00425
,4546860,DB00814,10084406,152,8135,56,3359,0.489669788,1.120734207,0.817500764,1.555283683,0.653000704,DB0081410084406_,0.426177071,0.113984012,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,meloxicam,DB00814
,4547520,DB00268,10084406,55,2920,30,1515,0.818288433,0.951209678,0.596105959,1.544476768,0.90302544,DB0026810084406_,0.102004553,-0.050020759,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ropinirole,DB00268
,4547521,DB00646,10084406,39,3414,13,1987,0.083956089,1.745881362,0.909641928,3.573793053,0.185001116,DB0064610084406_,1.687393422,0.557259507,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,nystatin,DB00646
,4547522,DB00715,10084406,56,4787,37,2250,0.11758715,0.711404527,0.459890965,1.112095464,0.237560297,DB0071510084406_,1.437333806,-0.340514056,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,paroxetine,DB00715
,4547523,DB13867,10084406,106,4444,53,2501,0.505009008,1.125562913,0.798832877,1.602290837,0.665985333,DB1386710084406_,0.406487631,0.118283278,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fluticasone,DB13867
,4548074,DB00688,10084406,64,6426,23,5355,0.00032666,2.318628315,1.417667489,3.919038584,0.002163602,DB0068810084406_,6.135980881,0.840975767,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,mycophenolate mofetil,DB00688
,4548284,DB00421,10084406,175,8728,42,5210,1.50484062442718e-08,2.487061491,1.763761886,3.57769082,3.24352077187933e-07,DB0042110084406_,14.94143625,0.91110189,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,spironolactone,DB00421
,4548286,DB00887,10084406,33,2308,32,1783,0.379515311,0.796720861,0.472837882,1.343950566,0.549541933,DB0088710084406_,0.598670197,-0.227250898,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,bumetanide,DB00887
,4549011,DB00196,10084406,64,5019,10,3275,1.73727974585265e-06,4.175568517,2.125801077,9.135733657,2.33996403380665e-05,DB0019610084406_,10.66278991,1.429250521,female,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fluconazole,DB00196
,4549012,DB00557,10084406,82,5905,30,3037,0.131421421,1.40573052,0.912697848,2.218194325,0.257782325,DB0055710084406_,1.355639752,0.340557111,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydroxyzine,DB00557
,4549013,DB01026,10084406,34,1076,22,1046,0.17524132,1.502081414,0.846969564,2.715267972,0.317757871,DB0102610084406_,1.146465598,0.406851756,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ketoconazole,DB01026
,4549970,DB00706,10084406,9,1066,201,15724,0.255075818,0.660462546,0.296823864,1.28406158,0.415741791,DB0070610084406_,0.877690905,-0.414814862,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tamsulosin,DB00706
,4549971,DB08820,10084406,24,4377,31,3514,0.101543875,0.621594868,0.348398069,1.096460927,0.213232172,DB0882010084406_,1.545373697,-0.475466736,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ivacaftor,DB08820
,4550034,DB01067,10084406,76,4285,46,4777,0.000989117,1.841735557,1.257421649,2.723479707,0.00545337,DB0106710084406_,5.211521598,0.610708365,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,glipizide,DB01067
,4550656,DB00843,10084406,31,2163,54,2119,0.011508796,0.562472779,0.348033401,0.894778126,0.039850801,DB0084310084406_,3.222612774,-0.575412538,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,donepezil,DB00843
,4550657,DB01275,10084406,56,3923,30,3319,0.049582567,1.579167881,0.993535815,2.555473072,0.124228175,DB0127510084406_,2.085635282,0.456898051,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,hydralazine,DB01275
,4550659,DB09263,10084406,46,1345,38,1682,0.074523869,1.513607803,0.957269087,2.40578283,0.169049397,DB0926310084406_,1.777564316,0.414496074,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,patiromer,DB09263
,4550671,DB00661,10084406,31,3497,19,1576,0.28660173,0.735335671,0.401098949,1.382258996,0.451367674,DB0066110084406_,0.795473029,-0.307428188,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,verapamil,DB00661
,4550697,DB01202,10084406,49,6665,50,5668,0.418151556,0.833418855,0.549444846,1.263522954,0.587189498,DB0120210084406_,0.532407686,-0.182218936,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,levetiracetam,DB01202
,4551666,DB01065,10084406,68,4263,42,3009,0.558627821,1.142734595,0.76430852,1.726279323,0.711514865,DB0106510084406_,0.340358969,0.133424158,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,melatonin,DB01065
,4552603,DB00316,10081576,50,65424,32,36921,0.567488815,0.881777202,0.554606592,1.420488786,0.718656942,DB0031610081576_,0.330371167,-0.125815861,NA,10081576,Product administration error,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,4553198,DB08932,10081576,46,19397,9,6588,0.161315931,1.735823653,0.838937519,4.035875528,0.299237068,DB0893210081576_,1.20651915,0.551482029,NA,10081576,Product administration error,10022117,"Injury, poisoning and procedural complications",Inj&P,macitentan,DB08932
,4555233,DB08932,10080714,120,19323,29,6568,0.10819513,1.406461832,0.930152244,2.19144236,0.223340715,DB0893210080714_,1.499056805,0.341077212,NA,10080714,Vascular device infection,10021881,Infections and infestations,Infec,macitentan,DB08932
,4556707,DB01075,10081572,52,19896,26,11071,0.723346314,1.112896928,0.681946045,1.857805849,0.837362718,DB0107510081572_,0.177497948,0.106966461,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,diphenhydramine,DB01075
,4556764,DB01225,10084406,39,5005,22,4618,0.07172626,1.635567429,0.944425692,2.900847624,0.164279045,DB0122510084406_,1.806188801,0.491989795,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,enoxaparin,DB01225
,4556765,DB09140,10084406,90,3651,26,1772,0.020819562,1.679902942,1.070994532,2.719157151,0.063781142,DB0914010084406_,2.75229772,0.518736019,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,oxygen,DB09140
,4556804,DB00656,10084406,192,11821,73,6546,0.006521114,1.456437395,1.104796502,1.937485046,0.0253056,DB0065610084406_,3.67672956,0.375993314,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,4556805,DB01175,10084406,205,10519,79,4813,0.219865043,1.18729359,0.909385458,1.562985836,0.373269993,DB0117510084406_,0.98545328,0.171676422,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,escitalopram,DB01175
,4556943,DB00482,10084406,92,8167,27,3044,0.30106614,1.269965178,0.817399279,2.033587318,0.467338315,DB0048210084406_,0.760701841,0.238989481,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,celecoxib,DB00482
,4557025,DB12159,10084406,131,2942,76,1992,0.311547855,1.167028397,0.867789632,1.578646652,0.479025691,DB1215910084406_,0.736001048,0.154460686,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,dupilumab,DB12159
,4557572,DB01240,10080714,95,5656,26,1550,1,1.001319064,0.640454992,1.61645132,1,DB0124010080714_,0,0.001318195,NA,10080714,Vascular device infection,10021881,Infections and infestations,Infec,epoprostenol,DB01240
,4557720,DB00227,10084406,38,2429,17,1786,0.099322806,1.643385392,0.901974597,3.11572001,0.209838039,DB0022710084406_,1.561419291,0.496758377,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lovastatin,DB00227
,4557753,DB05679,10081572,81,6850,63,4846,0.609863593,0.909580758,0.644931065,1.28783145,0.75213743,DB0567910081572_,0.284836219,-0.094771491,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,ustekinumab,DB05679
,4558646,DB06605,10084406,200,13873,129,12904,0.001256498,1.442071923,1.148412506,1.81606525,0.0066366,DB0660510084406_,5.015155458,0.366080915,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,4559733,DB00704,10084406,106,4250,122,5072,0.788256355,1.036910034,0.789019376,1.360886752,0.885308534,DB0070410084406_,0.121819068,0.036245169,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,naltrexone,DB00704
,4559734,DB00019,10080648,199,18813,137,9392,0.004334804,0.725139853,0.579600058,0.909506139,0.018230735,DB0001910080648_,4.004646381,-0.321390742,NA,10080648,Drug dose omission by device,10022117,"Injury, poisoning and procedural complications",Inj&P,pegfilgrastim,DB00019
,4561078,DB01015,10084406,80,9807,54,9327,0.056259579,1.408941156,0.984072929,2.030831156,0.136563977,DB0101510084406_,1.99096208,0.342838469,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sulfamethoxazole,DB01015
,4564083,DB00231,10084406,36,3260,15,2124,0.152655122,1.563558336,0.832492269,3.081820465,0.2876682,DB0023110084406_,1.245947545,0.446964209,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,temazepam,DB00231
,4564084,DB14500,10084406,123,7686,53,4020,0.262954603,1.213770339,0.870620516,1.712246794,0.424738016,DB1450010084406_,0.856282733,0.193731497,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,potassium,DB14500
,4565145,DB06403,10080714,71,21400,16,6645,0.311577528,1.377875344,0.792251986,2.541913208,0.479025691,DB0640310080714_,0.736001048,0.320542707,NA,10080714,Vascular device infection,10021881,Infections and infestations,Infec,ambrisentan,DB06403
,4565798,DB00341,10084406,142,11263,56,5012,0.485991005,1.128372174,0.82106433,1.569103238,0.649960453,DB0034110084406_,0.430843759,0.12077604,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cetirizine,DB00341
,4566646,DB00222,10084406,45,3161,24,3104,0.015407703,1.841006744,1.095011823,3.167797459,0.050353287,DB0022210084406_,2.988691383,0.610312565,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,glimepiride,DB00222
,4566939,DB00820,10080714,113,11802,20,5796,4.2364799563563e-06,2.774601219,1.712404198,4.719437187,5.10923953442649e-05,DB0082010080714_,9.881874891,1.020507032,female,10080714,Vascular device infection,10021881,Infections and infestations,Infec,tadalafil,DB00820
,4567018,DB00295,10084406,78,14585,38,9564,0.153203811,1.345980599,0.901338276,2.041057515,0.288474671,DB0029510084406_,1.243147993,0.297122817,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,morphine,DB00295
,4567720,DB01255,10084406,36,2097,17,1561,0.126302474,1.576182772,0.859005506,3.004173541,0.250513908,DB0125510084406_,1.38424084,0.455005957,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lisdexamfetamine,DB01255
,4568583,DB14513,10084406,107,7070,57,3507,0.676440015,0.931169632,0.667225224,1.311235328,0.80384645,DB1451310084406_,0.21834701,-0.071313815,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium,DB14513
,4568926,DB00722,10081572,62,25341,51,25981,0.259089718,1.246380896,0.846202964,1.843062313,0.420186533,DB0072210081572_,0.86705654,0.220244069,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,lisinopril,DB00722
,4568928,DB00904,10081572,49,23020,10,14446,0.000429399,3.074858242,1.5381212,6.811052996,0.002719041,DB0090410081572_,5.907475852,1.1232588,female,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,ondansetron,DB00904
,4569629,DB00727,10084406,38,3805,30,4143,0.222730892,1.379122066,0.830220828,2.309929292,0.376857515,DB0072710084406_,0.975888106,0.321447113,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,nitroglycerin,DB00727
,4570775,DB06605,10081572,45,14028,25,13008,0.041643874,1.669080928,1.00120789,2.841981811,0.10900311,DB0660510081572_,2.216378868,0.512273132,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,apixaban,DB06605
,4571994,DB01050,10081572,38,18070,13,9358,0.237013751,1.513766856,0.788309576,3.098552188,0.394357219,DB0105010081572_,0.930498134,0.414601151,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,ibuprofen,DB01050
,4572034,DB09153,10084406,35,7764,21,5678,0.500980047,1.218855388,0.689187615,2.206113412,0.662453996,DB0915310084406_,0.411804163,0.197912212,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sodium chloride,DB09153
,4572302,DB09045,10081572,47,2302,63,1661,0.001644045,0.538392455,0.358944829,0.802713886,0.008280869,DB0904510081572_,4.793807361,-0.619167515,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,dulaglutide,DB09045
,4572303,DB09045,10084406,48,2301,27,1697,0.289559867,1.311034643,0.798053007,2.194835251,0.454705087,DB0904510084406_,0.78810623,0.270816629,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,dulaglutide,DB09045
,4572851,DB00316,10058818,32,65442,29,36924,0.081935527,0.622566418,0.364735148,1.066897268,0.181606824,DB0031610058818_,1.705911235,-0.473904961,NA,10058818,Skin laceration,10022117,"Injury, poisoning and procedural complications",Inj&P,acetaminophen,DB00316
,4573241,DB00950,10084406,56,4662,18,2038,0.309173041,1.360022626,0.785256495,2.464586506,0.476536394,DB0095010084406_,0.741211182,0.307501337,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fexofenadine,DB00950
,4573242,DB01377,10084406,43,3753,17,2653,0.047533314,1.787887824,0.996136793,3.351398138,0.120454389,DB0137710084406_,2.116484111,0.581034936,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,magnesium oxide,DB01377
,4573243,DB09270,10084406,39,3075,27,2341,0.802814315,1.099667672,0.654077127,1.87383144,0.893313651,DB0927010084406_,0.112817527,0.095008018,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ubidecarenone,DB09270
,4573844,DB00422,10084406,31,3404,29,2920,0.79519915,0.91698681,0.533196575,1.581150357,0.889098203,DB0042210084406_,0.117547584,-0.086662191,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,methylphenidate,DB00422
,4574914,DB00165,10084406,36,2109,14,1352,0.143260835,1.648224468,0.863673185,3.320936083,0.274401447,DB0016510084406_,1.293163109,0.499698629,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pyridoxine,DB00165
,4574917,DB11133,10084406,40,2391,15,1559,0.071252954,1.738516743,0.93584144,3.400009969,0.163449307,DB1113310084406_,1.811252385,0.553032303,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,omega-3 fatty acids,DB11133
,4575166,DB00115,10081572,41,18384,26,10446,0.703094564,0.896032019,0.534806942,1.526604492,0.821845538,DB0011510081572_,0.196202811,-0.109779131,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,cyanocobalamin,DB00115
,4575277,DB00704,10081572,119,4237,147,5047,0.802932716,0.964280428,0.748123938,1.240882815,0.893342905,DB0070410081572_,0.11278478,-0.036373126,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,naltrexone,DB00704
,4579830,DB00331,10081572,87,24859,71,20681,0.936315661,1.019411068,0.736087212,1.415806861,0.976435515,DB0033110081572_,0.023846568,0.019225076,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,metformin,DB00331
,4581819,DB00443,10084406,42,2104,30,1160,0.319714405,0.771943724,0.46895158,1.284756682,0.487866278,DB0044310084406_,0.71771393,-0.258843628,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,betamethasone,DB00443
,4582441,DB00915,10084406,36,1419,23,1028,0.690226669,1.133837544,0.649311533,2.017304293,0.813142777,DB0091510084406_,0.206848567,0.125607936,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,amantadine,DB00915
,4582442,DB05316,10084406,222,4134,317,6678,0.173509553,1.131262742,0.944389004,1.353345456,0.315509405,DB0531610084406_,1.153566789,0.123334479,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,pimavanserin,DB05316
,4582563,DB00567,10084406,64,4455,19,2062,0.09632095,1.5589802,0.919281541,2.763177164,0.205213885,DB0056710084406_,1.5837025,0.444031889,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,cephalexin,DB00567
,4584368,DB06212,10081572,33,641,21,551,0.32954786,1.350467625,0.748404486,2.487044888,0.498212147,DB0621210081572_,0.696729295,0.300450922,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,tolvaptan,DB06212
,4584720,DB00332,10084406,42,2642,20,1636,0.35966957,1.300288642,0.743529634,2.346636054,0.52937405,DB0033210084406_,0.636060009,0.262586272,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ipratropium,DB00332
,4585041,DB00868,10084406,49,2935,23,1623,0.619863646,1.17802566,0.701188313,2.033843309,0.760489903,DB0086810084406_,0.273792444,0.163839867,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,benzonatate,DB00868
,4585383,DB06643,10081202,54,52367,7,7508,1,1.106035484,0.501499824,2.882309106,1,DB0664310081202_,0,0.100781986,NA,10081202,Incorrect route of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,denosumab,DB06643
,4586810,DB00737,10084406,41,2760,10,922,0.4198126,1.369507973,0.671273932,3.078382519,0.588733938,DB0073710084406_,0.529780916,0.314451532,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,meclizine,DB00737
,4586811,DB08868,10084406,65,9137,15,2496,0.681585997,1.183740243,0.666326061,2.238878266,0.807458612,DB0886810084406_,0.21386348,0.168679123,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,fingolimod,DB08868
,4587081,DB00804,10084406,44,2956,12,887,0.873728903,1.10022121,0.568151117,2.298782129,0.945081962,DB0080410084406_,0.056483623,0.09551126,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,dicyclomine,DB00804
,4587082,DB00916,10084406,46,5277,8,2423,0.007604553,2.639917054,1.231333823,6.486273013,0.028602084,DB0091610084406_,3.554275681,0.970747498,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,metronidazole,DB00916
,4589411,DB00571,10081578,98,5025,44,2565,0.531037912,1.136878566,0.786119275,1.667121415,0.687912749,DB0057110081578_,0.374093268,0.128286407,NA,10081578,Product administered to patient of inappropriate age,10022117,"Injury, poisoning and procedural complications",Inj&P,propranolol,DB00571
,4592408,DB01060,10077512,22,8565,30,5051,0.003576386,0.432488999,0.237436101,0.776225436,0.015589602,DB0106010077512_,4.161151131,-0.838198388,NA,10077512,End stage renal disease,10038359,Renal and urinary disorders,Renal,amoxicillin,DB01060
,4592831,DB01409,10081202,48,5983,28,3938,0.639870994,1.128355882,0.692362155,1.871127948,0.776931313,DB0140910081202_,0.252403333,0.120761601,NA,10081202,Incorrect route of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,tiotropium,DB01409
,4593609,DB00813,10081202,72,10500,142,10026,2.9889655225337e-07,0.48417261,0.358959352,0.648274141,4.87375674688575e-06,DB0081310081202_,12.23164551,-0.725313804,NA,10081202,Incorrect route of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,fentanyl,DB00813
,4595233,DB01307,10084406,34,2490,20,2049,0.271684756,1.398813316,0.779716487,2.573037294,0.434513771,DB0130710084406_,0.833527641,0.335624245,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,insulin detemir,DB01307
,4597435,DB01238,10084406,47,5203,29,3473,0.814419143,1.081814132,0.665423956,1.786137685,0.900478746,DB0123810084406_,0.104828717,0.078639384,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,aripiprazole,DB01238
,4599864,DB09292,10084406,19,4510,48,8214,0.250627712,0.720943265,0.399701889,1.251387421,0.410451677,DB0929210084406_,0.890497076,-0.327194834,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,sacubitril,DB09292
,4602286,DB01041,10084406,36,3009,20,3098,0.03098188,1.853046227,1.041656694,3.386633341,0.0868881,DB0104110084406_,2.4431342,0.616830894,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,thalidomide,DB01041
,4603227,DB00678,10081572,53,15546,22,10702,0.045712834,1.658405644,0.990810374,2.865337611,0.116928945,DB0067810081572_,2.146188837,0.505856686,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,losartan,DB00678
,4603780,DB00230,10080359,87,19587,22,8629,0.021349832,1.742133944,1.08039172,2.923761013,0.065117235,DB0023010080359_,2.731566014,0.555110766,NA,10080359,Product dispensing error,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,4604806,DB00537,10084406,77,7480,18,4280,0.000350194,2.44755093,1.448472306,4.352156646,0.002295099,DB0053710084406_,6.076979364,0.895087904,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,ciprofloxacin,DB00537
,4605218,DB00028,10081572,57,13401,20,5595,0.616285468,1.189872143,0.703248889,2.093118271,0.757494018,DB0002810081572_,0.277739638,0.173845858,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,human immunoglobulin g,DB00028
,4605535,DB00996,10081572,88,38865,53,22372,0.79335999,0.955785066,0.671884002,1.371055191,0.887941952,DB0099610081572_,0.118848907,-0.045222218,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,gabapentin,DB00996
,4605983,DB00121,10084406,68,4155,7,461,1,1.077796675,0.491687464,2.798492476,1,DB0012110084406_,0,0.074918841,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,biotin,DB00121
,4609294,DB00555,10084406,66,6981,24,3462,0.21649107,1.363754663,0.841515203,2.27989059,0.369271108,DB0055510084406_,0.996224195,0.310241677,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,lamotrigine,DB00555
,4612930,DB00571,10081572,92,5031,26,2583,0.005941258,1.816579591,1.161165486,2.933749057,0.023483603,DB0057110081572_,3.751452832,0.596955387,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,propranolol,DB00571
,4614820,DB00972,10084406,38,2466,12,1167,0.285007847,1.498428654,0.76305831,3.161917078,0.449584784,DB0097210084406_,0.799430824,0.404416995,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,azelastine,DB00972
,4619679,DB00697,10084406,132,5964,31,1775,0.258883999,1.267237712,0.84815823,1.946687382,0.41997053,DB0069710084406_,0.867570736,0.236839502,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tizanidine,DB00697
,4634145,DB00656,10081572,52,11961,14,6605,0.014206171,2.050999293,1.119031506,4.01070379,0.047132749,DB0065610081572_,3.054787222,0.718327134,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,trazodone,DB00656
,4644167,DB01043,10084406,18,1383,34,1376,0.03482415,0.526852139,0.278688028,0.964774096,0.09508183,DB0104310084406_,2.353017395,-0.64083534,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,memantine,DB01043
,4645544,DB00190,10081572,35,3262,24,4650,0.007412863,2.078695536,1.199228726,3.660143629,0.028029504,DB0019010081572_,3.574497623,0.731740551,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,carbidopa,DB00190
,4645837,DB00370,10084406,77,4464,41,3622,0.031759643,1.523732054,1.027206598,2.28961021,0.088554388,DB0037010084406_,2.424138358,0.421162624,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,mirtazapine,DB00370
,4663578,DB06605,10080714,33,14040,18,13015,0.069675268,1.699449824,0.928969455,3.207404148,0.16072088,DB0660510080714_,1.828086082,0.530304565,NA,10080714,Vascular device infection,10021881,Infections and infestations,Infec,apixaban,DB06605
,4676636,DB11834,10063829,31,911,23,765,0.679733491,1.131726634,0.632814012,2.051262064,0.80629196,DB1183410063829_,0.215309369,0.123744461,NA,10063829,Device malfunction,10077536,Product issues,Prod,guselkumab,DB11834
,4686951,DB08904,10081572,103,11507,32,3527,0.919012706,0.986576592,0.65651541,1.519318404,0.964244331,DB0890410081572_,0.036410561,-0.013514316,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,certolizumab pegol,DB08904
,4690258,DB01373,10080231,124,22596,12,7369,4.88220868738379e-06,3.369916417,1.860325636,6.702179065,5.79101332797306e-05,DB0137310080231_,9.756618175,1.214887942,female,10080231,Recalled product,10077536,Product issues,Prod,calcium,DB01373
,4739799,DB00230,10081572,42,19632,14,8637,0.467693467,1.319779931,0.706126448,2.618071203,0.634215842,DB0023010081572_,0.455365937,0.277465004,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,4742755,DB01156,10078489,30,13592,22,6306,0.10280857,0.632668449,0.35262091,1.152067247,0.215213097,DB0115610078489_,1.536126592,-0.457808772,NA,10078489,Postmortem blood drug level increased,10022891,Investigations,Inv,bupropion,DB01156
,4751493,DB00028,10084406,58,13400,24,5591,1,1.008328458,0.616029257,1.698827972,1,DB0002810084406_,0,0.008293968,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,human immunoglobulin g,DB00028
,4751878,DB09071,10084406,68,916,29,753,0.003193723,1.926888107,1.215912005,3.121804054,0.014241581,DB0907110084406_,4.251589331,0.655906322,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,tasimelteon,DB09071
,4764618,DB01190,10084406,39,4895,15,2270,0.659750841,1.205671672,0.648254012,2.359443647,0.792178916,DB0119010084406_,0.232968009,0.187036816,NA,10084406,Product dose omission issue,10022117,"Injury, poisoning and procedural complications",Inj&P,clindamycin,DB01190
,4807321,DB12332,10076476,55,3455,16,62,6.34963693183448e-13,0.061856313,0.032682587,0.122268288,2.91528745420558e-11,DB1233210076476_,24.2584676,-2.782941119,male,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,rucaparib,DB12332
,4876060,DB09071,10081581,38,946,36,746,0.474037728,0.832484001,0.508096091,1.36619561,0.63978996,DB0907110081581_,0.446615344,-0.183341276,NA,10081581,Incorrect product administration duration,10022117,"Injury, poisoning and procedural complications",Inj&P,tasimelteon,DB09071
,4908106,DB00230,10081770,79,19595,39,8612,0.548988731,0.890279166,0.598754198,1.34335601,0.703430282,DB0023010081770_,0.351786509,-0.116220196,NA,10081770,Product prescribing error,10022117,"Injury, poisoning and procedural complications",Inj&P,pregabalin,DB00230
,5083007,DB09035,10076308,390,4336,415,6275,3.14586249836586e-05,1.359946272,1.174840247,1.573993889,0.000295687,DB0903510076308_,8.126207569,0.307445193,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,nivolumab,DB09035
,5087055,DB08904,10081770,41,11569,13,3546,0.87316865,0.966681461,0.507105841,1.968531661,0.944720193,DB0890410081770_,0.056866487,-0.033886247,NA,10081770,Product prescribing error,10022117,"Injury, poisoning and procedural complications",Inj&P,certolizumab pegol,DB08904
,5124902,DB09071,10082201,36,948,28,754,1,1.022593313,0.600642291,1.757085951,1,DB0907110082201_,0,0.022341864,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,tasimelteon,DB09071
,5125867,DB05676,10082201,186,46943,139,25190,0.003520952,0.718083806,0.572973398,0.901585057,0.015396049,DB0567610082201_,4.173644353,-0.331168996,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,5126327,DB00005,10082201,317,127765,136,42283,0.012302956,0.771391795,0.628855867,0.950414606,0.041984185,DB0000510082201_,3.170462269,-0.259558869,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,5126329,DB00005,10082200,303,127779,101,42318,0.954076869,0.993543493,0.790482882,1.257577038,0.991966714,DB0000510082200_,0.008065727,-0.00647744,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,etanercept,DB00005
,5127040,DB08895,10082200,243,27871,68,6578,0.218281576,0.843442379,0.641173329,1.122105941,0.371469439,DB0889510082200_,0.990288681,-0.170263691,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,5127376,DB00051,10082200,106,25625,33,11387,0.07999492,1.42739766,0.956983238,2.180136526,0.178403739,DB0005110082200_,1.723706103,0.355852968,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,5127377,DB00563,10082200,306,46340,75,15273,0.020253797,1.344686141,1.040740629,1.75623671,0.06242259,DB0056310082200_,2.77382805,0.296160633,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,5129622,DB00476,10082200,52,17205,19,6158,0.893566636,0.979568543,0.568924124,1.755918899,0.955670726,DB0047610082200_,0.045341854,-0.020643067,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,duloxetine,DB00476
,5129626,DB00996,10082200,81,38872,27,22398,0.012288263,1.728581,1.105638379,2.781213176,0.041947662,DB0099610082200_,3.17133259,0.547300841,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,5131460,DB00563,10082201,150,46496,51,15297,0.869954798,0.967634055,0.69950932,1.357770954,0.942182195,DB0056310082201_,0.05955661,-0.032901306,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,methotrexate,DB00563
,5131993,DB00316,10082201,46,65428,31,36922,0.4767471,0.837380679,0.519592557,1.366297283,0.642120239,DB0031610082201_,0.442979705,-0.177476498,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,5132392,DB09029,10082201,43,11301,27,7243,1,1.020719054,0.6158938,1.719534479,1,DB0902910082201_,0,0.020507333,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,5132739,DB00635,10082201,47,33006,20,23774,0.047856531,1.69266937,0.983351169,3.016691358,0.121080847,DB0063510082201_,2.1112968,0.526306792,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,5133516,DB05679,10082201,41,6890,33,4876,0.636275726,0.879265733,0.541532239,1.437551545,0.773906548,DB0567910082201_,0.256304152,-0.128668115,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,ustekinumab,DB05679
,5134473,DB00316,10082490,47,65427,33,36920,0.35230745,0.803704887,0.504042778,1.29504803,0.522058678,DB0031610082490_,0.649975288,-0.218523134,NA,10082490,Taste disorder,10029205,Nervous system disorders,Nerv,acetaminophen,DB00316
,5134474,DB00338,10082490,41,33633,28,22244,0.902563511,0.968423097,0.58438166,1.626600726,0.957195726,DB0033810082490_,0.043747388,-0.032086203,NA,10082490,Taste disorder,10029205,Nervous system disorders,Nerv,omeprazole,DB00338
,5134726,DB00316,10082200,116,65358,44,36909,0.02585017,1.488802698,1.043554392,2.1578232,0.07535452,DB0031610082200_,2.58555137,0.397972238,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,acetaminophen,DB00316
,5134727,DB00331,10082200,54,24892,34,20718,0.238371241,1.321903239,0.84474261,2.094896066,0.396028504,DB0033110082200_,0.926269089,0.279072546,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,metformin,DB00331
,5134729,DB00451,10082200,79,47192,19,15400,0.290127035,1.356807943,0.813984315,2.372454925,0.455310116,DB0045110082200_,0.786776519,0.30513484,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,5134734,DB01050,10082200,43,18065,13,9358,0.091412522,1.713414126,0.903823532,3.474851589,0.19752379,DB0105010082200_,1.621896246,0.538487945,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,ibuprofen,DB01050
,5135629,DB00193,10082200,49,19271,12,8690,0.07050479,1.841289249,0.964599379,3.80556527,0.162202165,DB0019310082200_,1.818911788,0.610466005,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,tramadol,DB00193
,5135992,DB00051,10082201,110,25621,43,11377,0.538973732,1.135932398,0.79110302,1.65717559,0.694831749,DB0005110082201_,0.36408555,0.127453809,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,adalimumab,DB00051
,5136119,DB00480,10082201,28,67400,41,67621,0.147970619,0.685171291,0.408006435,1.135231531,0.28116878,DB0048010082201_,1.26880015,-0.378086412,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,lenalidomide,DB00480
,5136463,DB00230,10082200,304,19370,161,8490,0.060200569,0.827635477,0.680238668,1.009942042,0.14383892,DB0023010082200_,1.939061218,-0.189182466,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,pregabalin,DB00230
,5136467,DB00722,10082200,45,25358,38,25994,0.382301183,1.213904842,0.770342753,1.921824478,0.552389115,DB0072210082200_,0.593502563,0.193842306,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,lisinopril,DB00722
,5137243,DB00338,10082201,33,33641,21,22251,1,1.03938499,0.583551364,1.891008533,1,DB0033810082201_,0,0.038629183,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,5137247,DB00996,10082201,30,38923,26,22399,0.128467842,0.664036162,0.379447089,1.169161987,0.25346131,DB0099610082201_,1.372544091,-0.409418671,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,gabapentin,DB00996
,5138067,DB08895,10082201,105,28009,28,6618,0.580507432,0.88603386,0.57876386,1.398067944,0.728979664,DB0889510082201_,0.316109443,-0.121000112,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,tofacitinib,DB08895
,5138730,DB00480,10082490,180,67248,159,67503,0.253538553,1.136366456,0.912693201,1.415941961,0.414044972,DB0048010082490_,0.881780682,0.127835853,NA,10082490,Taste disorder,10029205,Nervous system disorders,Nerv,lenalidomide,DB00480
,5138925,DB00338,10082200,64,33610,27,22245,0.053420041,1.568831675,0.985785626,2.560145097,0.131400504,DB0033810082200_,2.029505338,0.450331186,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,omeprazole,DB00338
,5139153,DB11915,10082201,55,2276,24,1351,0.239668605,1.360191204,0.823531538,2.309162492,0.397494354,DB1191510082201_,0.922574548,0.307625281,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,valbenazine,DB11915
,5139585,DB05676,10082200,132,46997,90,25239,0.090451794,0.787670777,0.597708391,1.041923232,0.195963356,DB0567610082200_,1.629827596,-0.238675073,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,apremilast,DB05676
,5140723,DB00451,10082490,47,47224,17,15402,0.771375102,0.901691847,0.508077405,1.675660214,0.874834188,DB0045110082490_,0.13372091,-0.10348245,NA,10082490,Taste disorder,10029205,Nervous system disorders,Nerv,levothyroxine,DB00451
,5141242,DB00635,10082200,49,33004,31,23763,0.650434482,1.138031314,0.71107674,1.84691838,0.785013507,DB0063510082200_,0.242054356,0.129299852,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,prednisone,DB00635
,5141321,DB00451,10082201,55,47216,12,15407,0.25560765,1.495539779,0.791055463,3.069347228,0.416380217,DB0045110082201_,0.876156454,0.402487198,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,levothyroxine,DB00451
,5141920,DB05316,10082201,23,4333,37,6958,1,0.998209992,0.565476074,1.727718411,1,DB0531610082201_,0,-0.001791612,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,pimavanserin,DB05316
,5144237,DB11915,10082200,49,2282,17,1358,0.0547498,1.715034022,0.965897704,3.19001119,0.13392569,DB1191510082200_,2.010470187,0.539432918,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,valbenazine,DB11915
,5146859,DB00264,10082200,42,29565,21,24871,0.0571886,1.682442268,0.973901565,2.991529889,0.13816198,DB0026410082200_,1.979328513,0.520246469,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,metoprolol,DB00264
,5148644,DB00381,10082490,39,29321,23,22864,0.307834057,1.322231467,0.770044206,2.319724193,0.47502961,DB0038110082490_,0.74437814,0.279320815,NA,10082490,Taste disorder,10029205,Nervous system disorders,Nerv,amlodipine,DB00381
,5149420,DB00115,10082200,36,18389,14,10458,0.242490235,1.462377588,0.769321256,2.936530588,0.40069503,DB0011510082200_,0.914554666,0.380063596,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,cyanocobalamin,DB00115
,5150246,DB01076,10082200,53,25694,31,25552,0.021332882,1.700201265,1.07114886,2.741350402,0.065086393,DB0107610082200_,2.732039766,0.530746635,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,atorvastatin,DB01076
,5150486,DB09029,10082200,80,11264,51,7219,1,1.00531952,0.697942895,1.459632646,1,DB0902910082200_,0,0.005305422,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,secukinumab,DB09029
,5175936,DB00264,10082490,34,29573,27,24865,0.897927158,1.058799782,0.61989334,1.824942515,0.956338178,DB0026410082490_,0.044643686,0.057135985,NA,10082490,Taste disorder,10029205,Nervous system disorders,Nerv,metoprolol,DB00264
,5175947,DB00904,10082490,45,23024,21,14435,0.311424924,1.343463518,0.783472229,2.37531603,0.478940472,DB0090410082490_,0.736178966,0.295250994,NA,10082490,Taste disorder,10029205,Nervous system disorders,Nerv,ondansetron,DB00904
,5175948,DB00996,10082490,35,38918,21,22404,0.890147273,0.959476178,0.543035386,1.734958733,0.954474925,DB0099610082490_,0.046593907,-0.041367791,NA,10082490,Taste disorder,10029205,Nervous system disorders,Nerv,gabapentin,DB00996
,5175949,DB01234,10082490,63,31562,53,32835,0.265664459,1.236615777,0.844221586,1.817555026,0.427748258,DB0123410082490_,0.849220438,0.212378436,NA,10082490,Taste disorder,10029205,Nervous system disorders,Nerv,dexamethasone,DB01234
,5186313,DB08904,10082201,53,11557,13,3546,0.561001095,1.250886671,0.671736735,2.504237611,0.713534974,DB0890410082201_,0.337523826,0.223852637,NA,10082201,Therapeutic product effect decreased,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,5186989,DB00169,10082200,52,38639,13,18162,0.045018973,1.880154157,1.009206922,3.764643374,0.115603039,DB0016910082200_,2.157593037,0.631353772,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,cholecalciferol,DB00169
,5195162,DB01240,10068003,81,5670,19,1557,0.624367753,1.170650891,0.701037694,2.050458297,0.764203597,DB0124010068003_,0.268921037,0.157559911,NA,10068003,Catheter site irritation,10018065,General disorders and administration site conditions,Genrl,epoprostenol,DB01240
,5199083,DB00787,10082490,41,16959,42,17206,1,0.990407839,0.627762237,1.561553919,1,DB0078710082490_,0,-0.009638462,NA,10082490,Taste disorder,10029205,Nervous system disorders,Nerv,acyclovir,DB00787
,5199414,DB00203,10068003,47,13831,14,8924,0.008535913,2.166013205,1.171541886,4.262683582,0.031368956,DB0020310068003_,3.461936526,0.772888245,NA,10068003,Catheter site irritation,10018065,General disorders and administration site conditions,Genrl,sildenafil,DB00203
,5199417,DB08932,10068003,49,19394,16,6581,1,1.039226084,0.580493719,1.959149766,1,DB0893210068003_,0,0.038476286,NA,10068003,Catheter site irritation,10018065,General disorders and administration site conditions,Genrl,macitentan,DB08932
,5209720,DB00381,10082200,30,29330,24,22863,1,0.974378122,0.550564641,1.742023815,1,DB0038110082200_,0,-0.025955835,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,amlodipine,DB00381
,5240418,DB08904,10082200,58,11552,23,3536,0.293907161,0.771903883,0.468018147,1.31324993,0.459623378,DB0890410082200_,0.777347868,-0.258895241,NA,10082200,Therapeutic product effect incomplete,10018065,General disorders and administration site conditions,Genrl,certolizumab pegol,DB08904
,5246616,DB00210,10081572,47,838,12,337,0.184433974,1.574553797,0.809853269,3.303050516,0.329449338,DB0021010081572_,1.11033269,0.453971929,NA,10081572,Inappropriate schedule of product administration,10022117,"Injury, poisoning and procedural complications",Inj&P,adapalene,DB00210
,5331130,DB06404,10076476,53,3016,14,886,0.882970816,1.112086633,0.604779412,2.180911261,0.951066996,DB0640410076476_,0.050170771,0.1062381,NA,10076476,Product use in unapproved indication,10022117,"Injury, poisoning and procedural complications",Inj&P,human c1-esterase inhibitor,DB06404
,5406501,DB01254,10076308,32,3435,46,3102,0.051961546,0.628263195,0.386118819,1.010988881,0.12874062,DB0125410076308_,2.049955598,-0.464796101,NA,10076308,Intentional product use issue,10022117,"Injury, poisoning and procedural complications",Inj&P,dasatinib,DB01254
,5468542,DB00316,10082458,119,65355,64,36889,0.817311773,1.049509088,0.767955307,1.445695153,0.902326478,DB0031610082458_,0.102778876,0.04832252,NA,10082458,Suspected suicide,10037175,Psychiatric disorders,Psych,acetaminophen,DB00316
,5470770,DB09302,10079315,39,2159,14,1533,0.034091706,1.977656911,1.046101817,3.957390688,0.093587519,DB0930210079315_,2.368858249,0.681912766,NA,10079315,Device operational issue,10077536,Product issues,Prod,alirocumab,DB09302
,5545117,DB00768,10066901,624,1291,234,450,0.448707859,0.929539382,0.769990143,1.123653477,0.616307993,DB0076810066901_,0.484008452,-0.073066103,NA,10066901,Treatment failure,10018065,General disorders and administration site conditions,Genrl,olopatadine,DB00768
,5639130,DB00019,10064685,164,18848,122,9407,0.001028461,0.670910148,0.526837865,0.85638501,0.005637768,DB0001910064685_,5.178267035,-0.399120059,NA,10064685,Device occlusion,10077536,Product issues,Prod,pegfilgrastim,DB00019
,5728904,DB00019,10068383,71,18941,50,9479,0.066779627,0.710622159,0.48755475,1.042786201,0.155536085,DB0001910068383_,1.860877514,-0.341614412,NA,10068383,Drug delivery system malfunction,10077536,Product issues,Prod,pegfilgrastim,DB00019
,5729191,DB00136,10080231,171,1921,18,1664,6.61853293552896e-27,8.225655077,5.02275276,14.27104002,1.1715026142113e-24,DB0013610080231_,55.10375502,2.107257938,female,10080231,Recalled product,10077536,Product issues,Prod,calcitriol,DB00136
,5729192,DB05829,10080231,284,1322,40,169,0.631074704,0.907676218,0.623188434,1.346872988,0.769931936,DB0582910080231_,0.261453163,-0.096867552,NA,10080231,Recalled product,10077536,Product issues,Prod,parathyroid hormone,DB05829
,5739465,DB06724,10080231,65,7864,6,3913,1.52773506432016e-06,5.390464487,2.343992892,15.24060024,2.09366611916868e-05,DB0672410080231_,10.77400881,1.684631557,female,10080231,Recalled product,10077536,Product issues,Prod,calcium carbonate,DB06724
,5760318,DB00019,10069880,130,18882,64,9465,0.93923879,1.018206521,0.748387985,1.397344562,0.978804305,DB0001910069880_,0.021423549,0.018042767,NA,10069880,Device physical property issue,10077536,Product issues,Prod,pegfilgrastim,DB00019
,5834750,DB15444,10013573,52,1364,16,1167,0.000182164,2.779489332,1.552067614,5.245835771,0.001332829,DB1544410013573_,6.620451853,1.022267217,female,10013573,Dizziness,10029205,Nervous system disorders,Nerv,elexacaftor,DB15444
,5835832,DB01212,10081540,40,1979,27,1914,0.175135321,1.432687879,0.853873899,2.438136375,0.317658638,DB0121210081540_,1.146777938,0.359552316,NA,10081540,Recalled product administered,10022117,"Injury, poisoning and procedural complications",Inj&P,ceftriaxone,DB01212
,5859713,DB15444,10036790,86,1330,93,1090,0.074194475,0.757949934,0.55233775,1.039152754,0.168518669,DB1544410036790_,1.78070874,-0.277137946,NA,10036790,Productive cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,elexacaftor,DB15444
,5863978,DB15444,10070608,95,1321,64,1119,0.188522458,1.257281303,0.896578295,1.772586627,0.334660148,DB1544410070608_,1.094639745,0.228951694,NA,10070608,Infective pulmonary exacerbation of cystic fibrosis,10021881,Infections and infestations,Infec,elexacaftor,DB15444
,5871587,DB15444,10019211,157,1259,104,1079,0.057307037,1.293655123,0.989464827,1.69669603,0.138390873,DB1544410019211_,1.977673182,0.25747164,NA,10019211,Headache,10029205,Nervous system disorders,Nerv,elexacaftor,DB15444
,5871589,DB15444,10028813,62,1354,27,1156,0.003364581,1.960014651,1.219287892,3.226858784,0.014831126,DB1544410028813_,4.211027211,0.672951948,NA,10028813,Nausea,10017947,Gastrointestinal disorders,Gastr,elexacaftor,DB15444
,5871590,DB15444,10047899,53,1363,34,1149,0.230210287,1.313939867,0.831828673,2.100417752,0.386172829,DB1544410047899_,0.951470266,0.273030156,NA,10047899,Weight increased,10022891,Investigations,Inv,elexacaftor,DB15444
,5872937,DB15444,10016256,62,1354,42,1141,0.315304984,1.243863824,0.820281255,1.902283454,0.482915249,DB1544410016256_,0.72791411,0.218222522,NA,10016256,Fatigue,10018065,General disorders and administration site conditions,Genrl,elexacaftor,DB15444
,5891076,DB15444,10000081,47,1369,32,1151,0.42217307,1.234765483,0.765659446,2.014110084,0.591231241,DB1544410000081_,0.525548068,0.21088106,NA,10000081,Abdominal pain,10017947,Gastrointestinal disorders,Gastr,elexacaftor,DB15444
,5892508,DB15444,10011224,95,1321,81,1102,0.937552323,0.978404627,0.711614272,1.34778821,0.977492476,DB1544410011224_,0.022764685,-0.021831965,NA,10011224,Cough,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,elexacaftor,DB15444
,5893404,DB15444,10037844,103,1313,62,1121,0.035785657,1.418168602,1.014024773,1.996733962,0.097071827,DB1544410037844_,2.332304087,0.349366323,NA,10037844,Rash,10040785,Skin and subcutaneous tissue disorders,Skin,elexacaftor,DB15444
,5910943,DB15444,10054112,44,1372,30,1153,0.408906945,1.23245668,0.752042756,2.04453406,0.578276912,DB1544410054112_,0.547702439,0.209009478,NA,10054112,Hospitalisation,10042613,Surgical and medical procedures,Surg,elexacaftor,DB15444
,5939035,DB15444,10035664,31,1385,21,1162,0.484552598,1.238405948,0.684986193,2.280812104,0.648694768,DB1544410035664_,0.432792984,0.213825027,NA,10035664,Pneumonia,10021881,Infections and infestations,Infec,elexacaftor,DB15444
,5945310,DB00043,10069217,43,6370,19,2281,0.469864281,0.810402039,0.461145732,1.475782496,0.636158577,DB0004310069217_,0.452307411,-0.210224811,NA,10069217,Needle issue,10077536,Product issues,Prod,omalizumab,DB00043
,5946023,DB15444,10012735,69,1347,54,1129,0.780943074,1.070975863,0.732300937,1.573013115,0.880700697,DB1544410012735_,0.127037442,0.068570255,NA,10012735,Diarrhoea,10017947,Gastrointestinal disorders,Gastr,elexacaftor,DB15444
,5946222,DB00555,10082458,47,7000,23,3463,1,1.010941223,0.600570666,1.747459228,1,DB0055510082458_,0,0.0108818,NA,10082458,Suspected suicide,10037175,Psychiatric disorders,Psych,lamotrigine,DB00555
,5946224,DB00722,10082458,34,25369,48,25984,0.184395123,0.725511949,0.453203038,1.149819207,0.329402325,DB0072210082458_,1.110475402,-0.320877737,NA,10082458,Suspected suicide,10037175,Psychiatric disorders,Psych,lisinopril,DB00722
,5946228,DB01224,10082458,47,8061,32,5885,0.819730556,1.072282488,0.668994039,1.738759368,0.903971709,DB0122410082458_,0.100957214,0.069789543,NA,10082458,Suspected suicide,10037175,Psychiatric disorders,Psych,quetiapine,DB01224
,5946238,DB00331,10082458,44,24902,67,20685,0.002114281,0.545520035,0.364026393,0.810250041,0.010182095,DB0033110082458_,4.587124449,-0.606015747,NA,10082458,Suspected suicide,10037175,Psychiatric disorders,Psych,metformin,DB00331
,5946291,DB00404,10082458,49,19843,15,9847,0.110910838,1.621044473,0.89350199,3.114027373,0.227463924,DB0040410082458_,1.480763628,0.483070678,NA,10082458,Suspected suicide,10037175,Psychiatric disorders,Psych,alprazolam,DB00404
,5946417,DB00381,10082458,47,29313,55,22832,0.045385798,0.665623511,0.440957718,1.001124934,0.116318809,DB0038110082458_,2.151420505,-0.407031067,NA,10082458,Suspected suicide,10037175,Psychiatric disorders,Psych,amlodipine,DB00381
,5946500,DB01156,10082458,65,13557,29,6299,0.911874085,1.041398879,0.661849918,1.675477765,0.960554907,DB0115610082458_,0.040244134,0.040564885,NA,10082458,Suspected suicide,10037175,Psychiatric disorders,Psych,bupropion,DB01156
,5952597,DB15444,10000087,80,1336,68,1115,0.932407953,0.981862739,0.694490811,1.3913686,0.973171181,DB1544410000087_,0.027195281,-0.018303757,NA,10000087,Abdominal pain upper,10017947,Gastrointestinal disorders,Gastr,elexacaftor,DB15444
,5959223,DB15444,10010774,45,1371,17,1166,0.004204421,2.250531908,1.255062717,4.218492911,0.017785984,DB1544410010774_,4.029344568,0.811166592,NA,10010774,Constipation,10017947,Gastrointestinal disorders,Gastr,elexacaftor,DB15444
,5961544,DB00264,10082458,52,29555,27,24865,0.042081375,1.620287908,0.99889658,2.684123317,0.109867565,DB0026410082458_,2.208479598,0.482603854,NA,10082458,Suspected suicide,10037175,Psychiatric disorders,Psych,metoprolol,DB00264
,5970171,DB00343,10082458,36,8700,18,5077,0.672479733,1.167144157,0.644871427,2.185616082,0.801129885,DB0034310082458_,0.221732191,0.154559874,NA,10082458,Suspected suicide,10037175,Psychiatric disorders,Psych,diltiazem,DB00343
,5979928,DB01050,10082458,38,18070,31,9340,0.074097741,0.633584433,0.383614601,1.05385111,0.168373384,DB0105010082458_,1.781571242,-0.456362008,NA,10082458,Suspected suicide,10037175,Psychiatric disorders,Psych,ibuprofen,DB01050
,6054114,DB00502,10014522,33,1361,39,1833,0.630431002,1.139554943,0.690603345,1.870227065,0.769328241,DB0050210014522_,0.26223756,0.130637785,NA,10014522,Embolism venous,10047065,Vascular disorders,Vasc,haloperidol,DB00502
,6056738,DB15444,10022000,56,1360,42,1141,0.606810504,1.118559572,0.730268671,1.724718771,0.749724511,DB1544410022000_,0.288049459,0.112041762,NA,10022000,Influenza,10021881,Infections and infestations,Infec,elexacaftor,DB15444
,6392556,DB00331,10066377,41,24905,24,20728,0.212244227,1.421802771,0.838638055,2.460903631,0.364067543,DB0033110066377_,1.010415871,0.351925624,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,metformin,DB00331
,6392557,DB00338,10066377,62,33612,24,22248,0.027003069,1.709906607,1.051560663,2.8656902,0.078027338,DB0033810066377_,2.550696033,0.536438753,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,omeprazole,DB00338
,6392565,DB00904,10066377,49,23020,22,14434,0.222460708,1.396532272,0.828190847,2.426601788,0.376545799,DB0090410066377_,0.976715596,0.333992215,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,ondansetron,DB00904
,6392797,DB00005,10066377,161,127921,60,42359,0.436529081,0.888529614,0.656540878,1.216314517,0.605129704,DB0000510066377_,0.502312457,-0.118187302,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,etanercept,DB00005
,6392798,DB00635,10066377,61,32992,31,23763,0.138250095,1.417286919,0.905140151,2.260548913,0.267306906,DB0063510066377_,1.319357819,0.348744423,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,prednisone,DB00635
,6393000,DB00480,10051905,39,67389,60,67602,0.043829471,0.652060072,0.424117766,0.992213469,0.113235468,DB0048010051905_,2.178285837,-0.427618587,NA,10051905,Coronavirus infection,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,6393047,DB06403,10066377,35,21436,18,6643,0.10371418,0.60259446,0.331891651,1.13100901,0.216571638,DB0640310066377_,1.529833895,-0.506510846,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,ambrisentan,DB06403
,6393135,DB00695,10066377,41,28008,27,20501,0.713701952,1.111538041,0.667250238,1.879701489,0.830201837,DB0069510066377_,0.186086431,0.105744679,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,furosemide,DB00695
,6393147,DB00051,10066377,282,25449,96,11324,0.024896739,1.307042294,1.032170115,1.667287041,0.073261481,DB0005110066377_,2.6137203,0.267766794,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,adalimumab,DB00051
,6395944,DB00158,10066377,51,16764,22,8082,0.709095151,1.117596414,0.665193031,1.93661044,0.826380878,DB0015810066377_,0.190699501,0.111180321,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,folic acid,DB00158
,6395946,DB00316,10066377,85,65389,44,36909,0.713817932,1.090428875,0.748942351,1.607375898,0.830288509,DB0031610066377_,0.185982038,0.086571082,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,acetaminophen,DB00316
,6395947,DB00451,10066377,57,47214,19,15400,0.894657987,0.978522765,0.573252611,1.742418671,0.955976233,DB0045110066377_,0.045022227,-0.021711227,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,levothyroxine,DB00451
,6395949,DB00996,10066377,57,38896,19,22406,0.042119813,1.728131459,1.012490699,3.077276253,0.109931416,DB0099610066377_,2.207898596,0.547040743,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,gabapentin,DB00996
,6395950,DB01076,10066377,37,25710,46,25537,0.324398858,0.798940678,0.503700989,1.259468893,0.492865755,DB0107610066377_,0.707518444,-0.224468581,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,atorvastatin,DB01076
,6397980,DB09029,10066377,53,11291,14,7256,0.002342634,2.432723481,1.3294791,4.751498433,0.011063359,DB0902910066377_,4.504116632,0.889011404,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,secukinumab,DB09029
,6399007,DB00213,10066377,45,18850,28,13393,0.635291037,1.141840183,0.696591732,1.901838678,0.773388829,DB0021310066377_,0.256973344,0.132641157,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,pantoprazole,DB00213
,6399010,DB00722,10066377,32,25371,23,26009,0.22474839,1.426274269,0.808681199,2.553216263,0.379452834,DB0072210066377_,0.969024975,0.355065638,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,lisinopril,DB00722
,6399411,DB08895,10066377,95,28019,14,6632,0.111893633,1.606123015,0.911005168,3.051198865,0.228943614,DB0889510066377_,1.474279532,0.47382321,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,tofacitinib,DB08895
,6404715,DB00381,10066377,39,29321,24,22863,0.377027356,1.267084383,0.742826838,2.203271918,0.54694873,DB0038110066377_,0.60340021,0.2367185,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,amlodipine,DB00381
,6409056,DB00563,10066377,60,46586,16,15332,0.508153981,1.234158458,0.701547933,2.296352094,0.66876728,DB0056310066377_,0.402319143,0.210389327,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,methotrexate,DB00563
,6413971,DB01281,10066377,64,8868,6,1792,0.075944376,2.15532906,0.935675269,6.10103264,0.171406313,DB0128110066377_,1.763718443,0.767943408,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,abatacept,DB01281
,6515067,DB00316,10084268,43,65431,31,36922,0.332705854,0.782741563,0.481806651,1.285200216,0.501687942,DB0031610084268_,0.689776982,-0.244952697,NA,10084268,COVID-19,10021881,Infections and infestations,Infec,acetaminophen,DB00316
,6515230,DB14761,10005483,84,1067,168,1629,0.05852389,0.763423825,0.573694559,1.009918337,0.140721808,DB1476110005483_,1.96097033,-0.26994193,NA,10005483,Blood creatinine increased,10022891,Investigations,Inv,remdesivir,DB14761
,6515251,DB14761,10069339,111,1040,217,1580,0.041346444,0.777183633,0.60438996,0.99516964,0.108424331,DB1476110069339_,2.22170276,-0.25207862,NA,10069339,Acute kidney injury,10038359,Renal and urinary disorders,Renal,remdesivir,DB14761
,6515303,DB14761,10021097,45,1106,68,1729,0.92172378,1.03454235,0.688161184,1.542466502,0.965412507,DB1476110021097_,0.035199801,0.033959155,NA,10021097,Hypotension,10047065,Vascular disorders,Vasc,remdesivir,DB14761
,6515317,DB14761,10038695,36,1115,82,1715,0.054367146,0.675356994,0.439877153,1.019132504,0.133181775,DB1476110038695_,2.016040356,-0.392513848,NA,10038695,Respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,remdesivir,DB14761
,6515612,DB00635,10084268,70,32983,115,23679,3.34307204439356e-08,0.436994884,0.319764137,0.593574685,6.68487247522896e-07,DB0063510084268_,14.21824852,-0.827833791,NA,10084268,COVID-19,10021881,Infections and infestations,Infec,prednisone,DB00635
,6515613,DB00688,10084268,44,6446,72,5306,0.000332056,0.503069247,0.337022623,0.743488698,0.002193813,DB0068810084268_,6.122114238,-0.68702745,NA,10084268,COVID-19,10021881,Infections and infestations,Infec,mycophenolate mofetil,DB00688
,6515614,DB00864,10084268,62,6807,124,8268,0.001372107,0.607336646,0.439544987,0.831832237,0.007144042,DB0086410084268_,4.941476544,-0.498672035,NA,10084268,COVID-19,10021881,Infections and infestations,Infec,tacrolimus,DB00864
,6515693,DB14761,10066377,30,1121,55,1742,0.500401517,0.847690347,0.520975548,1.355594302,0.66198872,DB1476110066377_,0.412506763,-0.165239867,NA,10066377,Therapy interrupted,10042613,Surgical and medical procedures,Surg,remdesivir,DB14761
,6522857,DB08910,10084268,21,16723,35,17453,0.107763213,0.62620291,0.346225948,1.10662346,0.222712505,DB0891010084268_,1.501873553,-0.468080824,NA,10084268,COVID-19,10021881,Infections and infestations,Infec,pomalidomide,DB08910
,6523529,DB01024,10084268,24,2187,43,2077,0.013462164,0.530146782,0.306557927,0.897068129,0.045104449,DB0102410084268_,3.098774386,-0.634601364,NA,10084268,COVID-19,10021881,Infections and infestations,Infec,mycophenolic acid,DB01024
,6523937,DB14761,10011906,73,1078,132,1665,0.334663594,0.854234182,0.626173312,1.158034535,0.503816299,DB1476110011906_,0.685543564,-0.157549905,NA,10011906,Death,10018065,General disorders and administration site conditions,Genrl,remdesivir,DB14761
,6524464,DB14761,10077692,94,1057,181,1616,0.091373076,0.794052358,0.604736683,1.037426309,0.197471022,DB1476110077692_,1.62216343,-0.230605878,NA,10077692,Liver function test increased,10022891,Investigations,Inv,remdesivir,DB14761
,6525092,DB14761,10033318,24,1127,35,1762,0.789088736,1.072048876,0.60660974,1.865397553,0.885694655,DB1476110033318_,0.121383021,0.069571654,NA,10033318,Oxygen saturation decreased,10022891,Investigations,Inv,remdesivir,DB14761
,6525567,DB14761,10001551,193,958,435,1362,1.2472949945524e-06,0.630881361,0.519450024,0.764429572,1.74342722317521e-05,DB1476110001551_,10.95707262,-0.460637452,NA,10001551,Alanine aminotransferase increased,10022891,Investigations,Inv,remdesivir,DB14761
,6525571,DB14761,10003481,137,1014,275,1522,0.010435557,0.747836996,0.595502736,0.936018452,0.036816137,DB1476110003481_,3.301819034,-0.290570245,NA,10003481,Aspartate aminotransferase increased,10022891,Investigations,Inv,remdesivir,DB14761
,6525786,DB14761,10038435,20,1131,37,1760,0.585364953,0.841231133,0.460109114,1.496068028,0.732891196,DB1476110038435_,0.310758024,-0.172888825,NA,10038435,Renal failure,10038359,Renal and urinary disorders,Renal,remdesivir,DB14761
,6525863,DB14761,10054889,44,1107,66,1731,0.84256716,1.042410793,0.689802376,1.562399827,0.919873642,DB1476110054889_,0.083518964,0.0415361,NA,10054889,Transaminases increased,10022891,Investigations,Inv,remdesivir,DB14761
,6526180,DB14761,10062237,36,1115,46,1751,0.360876007,1.228911814,0.766568036,1.956796849,0.53080279,DB1476110062237_,0.63336472,0.206129074,NA,10062237,Renal impairment,10038359,Renal and urinary disorders,Renal,remdesivir,DB14761
,6526188,DB14761,10060795,26,1125,67,1730,0.030275286,0.59684831,0.361805418,0.958348965,0.085287409,DB1476110060795_,2.461728441,-0.516092285,NA,10060795,Hepatic enzyme increased,10022891,Investigations,Inv,remdesivir,DB14761
,6526208,DB14761,10049438,23,1128,32,1765,0.677499772,1.124591654,0.624941485,1.994321968,0.80448507,DB1476110049438_,0.217552871,0.117419996,NA,10049438,General physical health deterioration,10018065,General disorders and administration site conditions,Genrl,remdesivir,DB14761
,6527327,DB00480,10084268,104,67324,108,67554,0.836744788,0.966244884,0.730844349,1.277041097,0.915684947,DB0048010084268_,0.088082918,-0.034337973,NA,10084268,COVID-19,10021881,Infections and infestations,Infec,lenalidomide,DB00480
,6527360,DB00207,10084268,30,9050,33,5422,0.01838936,0.544697728,0.320508027,0.922338322,0.057825615,DB0020710084268_,2.850323429,-0.607524265,NA,10084268,COVID-19,10021881,Infections and infestations,Infec,azithromycin,DB00207
,6527362,DB01611,10084268,33,11880,29,2332,2.66926430675307e-08,0.223401888,0.131239507,0.382214361,5.44521632153701e-07,DB0161110084268_,14.42335817,-1.498782941,male,10084268,COVID-19,10021881,Infections and infestations,Infec,hydroxychloroquine,DB01611
,6527406,DB14761,10006093,45,1106,76,1721,0.70426697,0.921362209,0.617666342,1.36091467,0.82270376,DB1476110006093_,0.195159094,-0.081902042,NA,10006093,Bradycardia,10007541,Cardiac disorders,Card,remdesivir,DB14761
,6528467,DB01234,10084268,32,31593,31,32857,0.802026738,1.073524983,0.634182329,1.819607387,0.892903305,DB0123410084268_,0.113276985,0.07094761,NA,10084268,COVID-19,10021881,Infections and infestations,Infec,dexamethasone,DB01234
,6528817,DB14761,10007515,49,1102,79,1718,0.926258431,0.966972849,0.65732508,1.410579756,0.968656741,DB1476110007515_,0.031844971,-0.033584861,NA,10007515,Cardiac arrest,10007541,Cardiac disorders,Card,remdesivir,DB14761
,6528983,DB14761,10013968,33,1118,34,1763,0.099074235,1.530265231,0.912889814,2.562710854,0.209457284,DB1476110013968_,1.563235457,0.425441074,NA,10013968,Dyspnoea,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,remdesivir,DB14761
,6529778,DB14761,10021143,36,1115,64,1733,0.602280386,0.874282259,0.560387504,1.345658966,0.746320005,DB1476110021143_,0.292600809,-0.134352004,NA,10021143,Hypoxia,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,remdesivir,DB14761
,6529944,DB00051,10084268,39,25692,24,11396,0.219194794,0.720783758,0.422484963,1.253625929,0.372517063,DB0005110084268_,0.987472436,-0.327416107,NA,10084268,COVID-19,10021881,Infections and infestations,Infec,adalimumab,DB00051
,6530197,DB14761,10018358,38,1113,54,1743,0.665049336,1.101988166,0.702862738,1.712686242,0.796135038,DB1476110018358_,0.227986461,0.097115972,NA,10018358,Glomerular filtration rate decreased,10022891,Investigations,Inv,remdesivir,DB14761
,6531099,DB14761,10065154,44,1107,89,1708,0.172319966,0.762854695,0.51484542,1.116333544,0.313908614,DB1476110065154_,1.158653375,-0.270687705,NA,10065154,Therapy cessation,10042613,Surgical and medical procedures,Surg,remdesivir,DB14761
,6531177,DB14761,10001052,15,1136,35,1762,0.241775623,0.664826143,0.335720446,1.256011382,0.399903864,DB1476110001052_,0.916531102,-0.408229712,NA,10001052,Acute respiratory distress syndrome,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,remdesivir,DB14761
,6531181,DB08932,10084268,39,19404,17,6580,0.441266885,0.777955588,0.429555891,1.467646229,0.609447499,DB0893210084268_,0.495202472,-0.251085841,NA,10084268,COVID-19,10021881,Infections and infestations,Infec,macitentan,DB08932
,6531753,DB08895,10084268,53,28061,10,6636,0.630758617,1.253359748,0.630585995,2.764787038,0.769617744,DB0889510084268_,0.261861323,0.225827744,NA,10084268,COVID-19,10021881,Infections and infestations,Infec,tofacitinib,DB08895
,6538848,DB00381,10084268,31,29329,22,22865,0.783031529,1.098560987,0.615694225,1.991799352,0.881832675,DB0038110084268_,0.125752951,0.09400113,NA,10084268,COVID-19,10021881,Infections and infestations,Infec,amlodipine,DB00381
,6541220,DB14761,10059570,26,1125,30,1767,0.269975616,1.361069522,0.76883079,2.395077061,0.432622634,DB1476110059570_,0.837889445,0.308270804,NA,10059570,Blood alkaline phosphatase increased,10022891,Investigations,Inv,remdesivir,DB14761
,6541247,DB14761,10010264,25,1126,38,1759,0.897095694,1.027747144,0.591134291,1.7583393,0.956338178,DB1476110010264_,0.044643686,0.027369168,NA,10010264,Condition aggravated,10018065,General disorders and administration site conditions,Genrl,remdesivir,DB14761
,6568974,DB14761,10001053,26,1125,33,1764,0.42220303,1.235290909,0.705406757,2.142471828,0.591257447,DB1476110001053_,0.525503744,0.211306497,NA,10001053,Acute respiratory failure,10038738,"Respiratory, thoracic and mediastinal disorders",Resp,remdesivir,DB14761